ContigID,length,GC,CpG,male_unique,female_unique,sex,Evalue,UniProt_Acc,Protein names,ProteinName,Gene ontology IDs,Gene ontology (GO),PFAM,evalue-GIG,Gigaton-ID,evalue-Ru,Ruphibase_ID,evalue-SIG,SigID,Cluster,Tissue-enriched-expression,sseqid3,Organism,GO comp100029_c1_seq1,288,50,0.66950614,15,11,,,,,,,,,6.00E-19,CHOYP_LOC412155.1.2,,,,,,,,, comp100065_c0_seq1,201,50.2488,0.88676471,1,10,,2.00E-08,Q5PRC1,Lipoma HMGIC fusion partner homolog,Lipoma HMGIC fusion partner homolog,GO:0016021,integral to membrane,PF10242;,,,,,,,,,LHFP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp100097_c0_seq1,679,43.0044,0.48675839,16,78,,2.00E-37,Q9UI26,Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11),Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11),GO:0005737; GO:0005634; GO:0008565; GO:0006610,cytoplasm; nucleus; protein transporter activity; ribosomal protein import into nucleus,PF03810;,,,,,,,,,IPO11_HUMAN,Homo sapiens (Human),ribosomal protein import into nucleus [GO:0006610]; transcription factor import into nucleus [GO:0042991] comp100097_c1_seq1,289,46.7128,0.70049148,1,25,,,,,,,,,6.00E-19,CHOYP_IPO11.1.1,,,,,,,,, comp100104_c2_seq1,422,36.9668,0.56372131,9,21,,3.00E-29,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,9.00E-25,CHOYP_SACS.9.17,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp100105_c1_seq1,863,47.0452,0.50379076,24,90,,2.00E-73,P18756,Protein c-ets-1-B (C-ets-1B) (XE1-B) (Fragment),Protein c-ets-1-B (C-ets-1B) (XE1-B) (Fragment),GO:0005634; GO:0010595; GO:0045765; GO:0043565; GO:0003700; GO:0006351,"nucleus; positive regulation of endothelial cell migration; regulation of angiogenesis; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;,6.00E-75,CHOYP_BRAFLDRAFT_125635.1.1,,,,,,,ETS1B_XENLA,Xenopus laevis (African clawed frog),"positive regulation of endothelial cell migration [GO:0010595]; regulation of angiogenesis [GO:0045765]; transcription, DNA-templated [GO:0006351]" comp100108_c1_seq1,1185,44.0506,0.50920164,31,74,,3.00E-59,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,3.00E-56,CHOYP_APLP.2.2,7.00E-36,ruditapes_c24094,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp100109_c0_seq1,701,39.2297,0.63310474,14,43,,6.00E-23,O75443,Alpha-tectorin,Alpha-tectorin,GO:0031225; GO:0007160; GO:0005201; GO:0005886; GO:0005578; GO:0007605,anchored to membrane; cell-matrix adhesion; extracellular matrix structural constituent; plasma membrane; proteinaceous extracellular matrix; sensory perception of sound,PF08742;PF06119;PF01826;PF12714;PF00094;PF00100;,,,,,,,,,TECTA_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605] comp100113_c0_seq1,381,40.4199,1.1628695,1,18,,2.00E-06,Q95US5,"Beta-1,3-galactosyltransferase bre-5 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 5) (Bt toxin-resistant protein 5)","Beta-1,3-galactosyltransferase bre-5 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 5) (Bt toxin-resistant protein 5)",GO:0000139; GO:0008376; GO:0016051; GO:0075015; GO:0008378; GO:0016021; GO:0045747; GO:0006486; GO:0009636,Golgi membrane; acetylgalactosaminyltransferase activity; carbohydrate biosynthetic process; formation of infection structure on or near host; galactosyltransferase activity; integral to membrane; positive regulation of Notch signaling pathway; protein glycosylation; response to toxic substance,PF01762;,,,,,,,,,BRE5_CAEEL,Caenorhabditis elegans,carbohydrate biosynthetic process [GO:0016051]; formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636] comp100113_c0_seq2,421,41.0926,0.98274527,0,2,,9.00E-13,Q9N295,"Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) (Fragment)","Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) (Fragment)",GO:0000139; GO:0005783; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; endoplasmic reticulum; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT5_PANTR,Pan troglodytes (Chimpanzee),protein glycosylation [GO:0006486] comp100113_c1_seq1,283,36.0424,1.42165811,0,21,,7.00E-09,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp100129_c0_seq1,351,47.0085,0.36688803,8,8,,9.00E-30,Q14644,Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein),Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein),GO:0005099; GO:0015278; GO:0005737; GO:0035556; GO:0031235; GO:0046872; GO:0046580; GO:0005543; GO:0007165,Ras GTPase activator activity; calcium-release channel activity; cytoplasm; intracellular signal transduction; intrinsic to internal side of plasma membrane; metal ion binding; negative regulation of Ras protein signal transduction; phospholipid binding; signal transduction,PF00779;PF00168;PF00169;PF00616;,,,,,,,,,RASA3_HUMAN,Homo sapiens (Human),MAPK cascade [GO:0000165]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165] comp100136_c0_seq1,278,46.4029,0.67262201,21,0,,,,,,,,,5.00E-13,CHOYP_TRIADDRAFT_57945.2.3,,,,,,,,, comp100141_c0_seq1,605,41.6529,0.34916869,34,54,,1.00E-65,O95847,Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27),Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27),GO:0045177; GO:0035356; GO:0006091; GO:0048839; GO:0016021; GO:0005743; GO:0043066; GO:0070997; GO:0043025; GO:0008284; GO:0051562; GO:0006810,apical part of cell; cellular triglyceride homeostasis; generation of precursor metabolites and energy; inner ear development; integral to membrane; mitochondrial inner membrane; negative regulation of apoptotic process; neuron death; neuronal cell body; positive regulation of cell proliferation; reduction of mitochondrial calcium ion concentration; transport,PF00153;,2.00E-23,CHOYP_LOC580090.1.1,,,,,,,UCP4_HUMAN,Homo sapiens (Human),generation of precursor metabolites and energy [GO:0006091]; proton transport [GO:0015992]; translation [GO:0006412] comp100174_c1_seq1,250,48.4,1.09788525,2,17,,9.00E-13,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,,,9.00E-71,ruditapes_c15835,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp100184_c0_seq2,458,42.7948,0.63621158,5,29,,3.00E-24,Q9C509,Sphingosine-1-phosphate lyase (S1PL) (SP-lyase) (SPL) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),Sphingosine-1-phosphate lyase (AtSPL1) (S1PL) (SP-lyase) (SPL) (EC 4.1.2.27) (Dihydrosphingosine phosphate lyase 1) (AtDPL1) (Sphingosine-1-phosphate aldolase),GO:0006915; GO:0016831; GO:0019752; GO:0005783; GO:0005789; GO:0016021; GO:0016020; GO:0030170; GO:0008117; GO:0030149,apoptotic process; carboxy-lyase activity; carboxylic acid metabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane; pyridoxal phosphate binding; sphinganine-1-phosphate aldolase activity; sphingolipid catabolic process,PF00282;,,,,,,,,,SGPL_ARATH,Arabidopsis thaliana (Mouse-ear cress),carboxylic acid metabolic process [GO:0019752]; sphingolipid catabolic process [GO:0030149] comp100187_c0_seq1,375,38.9333,0.49427582,13,0,,5.00E-35,Q16RI1,Protein OPI10 homolog,Protein OPI10 homolog,,,PF05603;,1.00E-23,CHOYP_BRAFLDRAFT_206907.7.11,,,,,,,OPI10_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp100218_c0_seq1,733,43.6562,0.43023018,19,54,,7.00E-16,Q9Y5Q9,General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),GO:0042791; GO:0003677; GO:0005654; GO:0042797; GO:0000127,5S class rRNA transcription from RNA polymerase III type 1 promoter; DNA binding; nucleoplasm; tRNA transcription from RNA polymerase III promoter; transcription factor TFIIIC complex,PF13181;,,,,,,,,,TF3C3_HUMAN,Homo sapiens (Human),"5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]" comp100239_c1_seq1,594,39.0572,0.91736307,6,67,,,,,,,,,1.00E-12,CHOYP_ZPR_4288.1.1,,,,,,,,, comp100287_c0_seq1,341,39.0029,0.23233895,5,48,,,,,,,,,2.00E-14,CHOYP_BRAFLDRAFT_67316.1.1,,,,,,,,, comp100297_c0_seq1,215,39.0698,0.24615917,0,2,,,,,,,,,2.00E-16,CHOYP_BRAFLDRAFT_273832.1.1,,,,,,,,, comp100298_c0_seq1,670,46.2687,0.8889336,21,102,,1.00E-17,A0R5M8,Histidine-specific methyltransferase EgtD (EC 2.1.1.44) (Histidine-alpha-N-methyltransferase),Histidine N-alpha-methyltransferase (EC 2.1.1.44) (Histidine trimethyltransferase),GO:0052707; GO:0030745; GO:0052704; GO:0008276,"N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine; dimethylhistidine N-methyltransferase activity; ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine; protein methyltransferase activity",PF10017;,,,9.00E-19,ruditapes_c23704,,,,,EGTD_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),"ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine [GO:0052704]; N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [GO:0052707]" comp100305_c0_seq1,229,41.4847,0.31364234,3,25,,1.00E-27,P06280,Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase),Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase),GO:0005794; GO:0004557; GO:0005576; GO:0016936; GO:0016139; GO:0046477; GO:0043202; GO:0045019; GO:0051001; GO:0009311; GO:0042803; GO:0052692; GO:0005102; GO:0044281,Golgi apparatus; alpha-galactosidase activity; extracellular region; galactoside binding; glycoside catabolic process; glycosylceramide catabolic process; lysosomal lumen; negative regulation of nitric oxide biosynthetic process; negative regulation of nitric-oxide synthase activity; oligosaccharide metabolic process; protein homodimerization activity; raffinose alpha-galactosidase activity; receptor binding; small molecule metabolic process,PF16499;,2.00E-18,CHOYP_LOC663249.1.1,,,,,,,AGAL_HUMAN,Homo sapiens (Human),glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] comp100366_c1_seq1,593,46.543,0.37525771,7,65,,1.00E-43,Q852M1,Probable aldehyde oxidase 2 (AO-2) (EC 1.2.3.1),Probable aldehyde oxidase 2 (AO-2) (EC 1.2.3.1),GO:0051537; GO:0009688; GO:0004031; GO:0009851; GO:0009055; GO:0050660; GO:0005506; GO:0016614,"2 iron, 2 sulfur cluster binding; abscisic acid biosynthetic process; aldehyde oxidase activity; auxin biosynthetic process; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; oxidoreductase activity, acting on CH-OH group of donors",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,7.00E-41,CHOYP_LOC100636568.1.1,,,,,,,ALDO2_ORYSJ,Oryza sativa subsp. japonica (Rice),abscisic acid biosynthetic process [GO:0009688]; auxin biosynthetic process [GO:0009851]; xanthine catabolic process [GO:0009115] comp100370_c0_seq1,830,38.6747,1.06580023,7,139,,6.00E-06,Q494W8,CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10),CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10),GO:0005230; GO:0016021,extracellular ligand-gated ion channel activity; integral to membrane,PF02931;PF02932;,,,,,,,,,CRFM7_HUMAN,Homo sapiens (Human), comp100387_c1_seq1,202,46.5347,1.04105115,0,11,,6.00E-06,H2A0N9,BPTI/Kunitz domain-containing protein 4 (Nacre serine protease inhibitor 3) (NSPI3),BPTI/Kunitz domain-containing protein 4 (Nacre serine protease inhibitor 3) (NSPI3),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF02822;PF00014;,,,,,,,,,KCP4_PINMG,Pinctada margaritifera (Black-lipped pearl oyster), comp100414_c0_seq1,416,35.8173,0.75298377,14,41,,2.00E-19,Q3V080,Zinc finger protein 583,Zinc finger protein 583,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN583_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp100414_c1_seq1,343,41.1079,0.55372704,11,31,,9.00E-22,Q9H116,GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336),GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336),GO:0001658; GO:0046872; GO:0000122; GO:0045892; GO:0005730; GO:0005654; GO:0043565; GO:0006351,"branching involved in ureteric bud morphogenesis; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleolus; nucleoplasm; sequence-specific DNA binding; transcription, DNA-dependent",PF00651;PF13912;,6.00E-20,CHOYP_GZF1.2.2,,,,,,,GZF1_HUMAN,Homo sapiens (Human),"branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp100439_c0_seq1,244,45.082,0.41610753,2,12,,,,,,,,,2.00E-29,CHOYP_SC6A8.1.1,,,,,,,,, comp100439_c1_seq1,573,42.2339,0.67204061,9,56,,3.00E-33,P58295,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015187; GO:0016021; GO:0005328,glycine transmembrane transporter activity; integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,SC6A5_RAT,Rattus norvegicus (Rat),"glycine import [GO:0036233]; glycine transport [GO:0015816]; synaptic transmission, glycinergic [GO:0060012]" comp100440_c0_seq1,711,39.5218,0.3251148,8,34,,2.00E-77,Q9JJW0,Peroxisomal membrane protein 4 (24 kDa peroxisomal intrinsic membrane protein),Peroxisomal membrane protein 4 (24 kDa peroxisomal intrinsic membrane protein),GO:0016021; GO:0005778,integral to membrane; peroxisomal membrane,PF02466;,1.00E-77,CHOYP_BRAFLDRAFT_214694.1.1,,,,,,,PXMP4_MOUSE,Mus musculus (Mouse), comp100442_c0_seq1,986,39.4523,1.25253936,26,109,,1.00E-35,Q02318,"Sterol 26-hydroxylase, mitochondrial (EC 1.14.13.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)","Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)",GO:0006699; GO:0036378; GO:0047749; GO:0031073; GO:0008203; GO:0020037; GO:0005506; GO:0005743; GO:0005759; GO:0008395; GO:0016125; GO:0030343; GO:0006805,bile acid biosynthetic process; calcitriol biosynthetic process from calciol; cholestanetriol 26-monooxygenase activity; cholesterol 26-hydroxylase activity; cholesterol metabolic process; heme binding; iron ion binding; mitochondrial inner membrane; mitochondrial matrix; steroid hydroxylase activity; sterol metabolic process; vitamin D3 25-hydroxylase activity; xenobiotic metabolic process,PF00067;,2.00E-11,CHOYP_LOC101175691.1.1,,,,,,,CP27A_HUMAN,Homo sapiens (Human),bile acid biosynthetic process [GO:0006699]; sterol metabolic process [GO:0016125] comp100466_c0_seq1,494,41.9028,0.43463593,17,58,,7.00E-09,Q9CRG1,Transmembrane 7 superfamily member 3 (NARP1),Transmembrane 7 superfamily member 3 (NARP1),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF13886;,,,,,,,,,TM7S3_MOUSE,Mus musculus (Mouse), comp100480_c0_seq1,254,43.7008,0.74562559,8,29,,2.00E-32,Q05688,Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment),Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment),GO:0005524; GO:0006955; GO:0051389; GO:0043559; GO:0043560; GO:0005520; GO:0005010; GO:0016021; GO:0043231; GO:0043066; GO:0043548; GO:0048015; GO:0045740; GO:0030335; GO:0046777; GO:0051262; GO:0046328,ATP binding; immune response; inactivation of MAPKK activity; insulin binding; insulin receptor substrate binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; integral to membrane; intracellular membrane-bounded organelle; negative regulation of apoptotic process; phosphatidylinositol 3-kinase binding; phosphatidylinositol-mediated signaling; positive regulation of DNA replication; positive regulation of cell migration; protein autophosphorylation; protein tetramerization; regulation of JNK cascade,PF00041;PF07714;,3.00E-40,CHOYP_VKR.1.1,,,,,,,IGF1R_BOVIN,Bos taurus (Bovine),inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328] comp100480_c1_seq1,306,45.7516,0.44752665,5,0,,1.00E-16,Q91571,Ephrin type-B receptor 1-A (EC 2.7.10.1) (Tyrosine-protein kinase receptor XEK),Ephrin type-B receptor 1-A (EC 2.7.10.1) (Tyrosine-protein kinase receptor XEK),GO:0005524; GO:0007411; GO:0060326; GO:0031589; GO:0030425; GO:0060997; GO:0031901; GO:0030010; GO:0005887; GO:0051965; GO:0046777; GO:0070372; GO:0046328; GO:0005005,ATP binding; axon guidance; cell chemotaxis; cell-substrate adhesion; dendrite; dendritic spine morphogenesis; early endosome membrane; establishment of cell polarity; integral to plasma membrane; positive regulation of synapse assembly; protein autophosphorylation; regulation of ERK1 and ERK2 cascade; regulation of JNK cascade; transmembrane-ephrin receptor activity,PF14575;PF01404;PF00041;PF07714;PF00536;,,,,,,,,,EPB1A_XENLA,Xenopus laevis (African clawed frog),axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328] comp100502_c1_seq1,374,40.107,0.8691451,0,45,,4.00E-14,Q04791,"Fatty acyl-CoA hydrolase precursor, medium chain (EC 3.1.2.-) (Thioesterase B)","Fatty acyl-CoA hydrolase precursor, medium chain (EC 3.1.2.-) (Thioesterase B)",GO:0006633; GO:0016787,fatty acid biosynthetic process; hydrolase activity,PF00135;,,,,,,,,,SASB_ANAPL,Anas platyrhynchos (Mallard) (Anas boschas),fatty acid biosynthetic process [GO:0006633] comp100517_c1_seq1,1285,40.856,0.45014904,27,99,,4.00E-36,Q8IZJ1,Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1),Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1),GO:0033564; GO:0006915; GO:0007411; GO:0016021; GO:2001240; GO:0043065; GO:0007165,anterior/posterior axon guidance; apoptotic process; axon guidance; integral to membrane; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of apoptotic process; signal transduction,PF00531;PF07679;PF00090;PF00791;,5.00E-78,CHOYP_LOC100569275.1.1,,,,,,,UNC5B_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; signal transduction [GO:0007165] comp100523_c0_seq1,596,38.0872,1.02834615,9,64,,4.00E-15,Q02338,"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase)","D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)",GO:0003858; GO:0060612; GO:0007420; GO:0044255; GO:0046951; GO:0046952; GO:0001889; GO:0005743; GO:0005759; GO:0005634; GO:0005543; GO:0046686; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0060416; GO:0032868; GO:0007584; GO:0042594; GO:0009636,3-hydroxybutyrate dehydrogenase activity; adipose tissue development; brain development; cellular lipid metabolic process; ketone body biosynthetic process; ketone body catabolic process; liver development; mitochondrial inner membrane; mitochondrial matrix; nucleus; phospholipid binding; response to cadmium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to growth hormone stimulus; response to insulin stimulus; response to nutrient; response to starvation; response to toxic substance,PF00106;,,,3.00E-17,ruditapes_c11402,,,,,BDH_HUMAN,Homo sapiens (Human),adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636] comp100540_c0_seq1,541,40.2957,0.61823498,14,43,,4.00E-59,Q8N4P3,"Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)","Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)",GO:0008893; GO:0008152; GO:0046872,"guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; metabolic process; metal ion binding",PF13328;,,,,,,,,,MESH1_HUMAN,Homo sapiens (Human),guanosine tetraphosphate metabolic process [GO:0015969]; response to starvation [GO:0042594] comp100564_c0_seq1,1415,43.3922,0.67634012,3,0,,,,,,,,,1.00E-104,CHOYP_OTU5B.1.1,,,,,,,,, comp100564_c0_seq2,2047,41.1822,0.63551544,19,46,,9.00E-120,Q2YDU3,OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA),OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA),GO:0071108; GO:0070536; GO:0006508; GO:0032496; GO:0004843,protein K48-linked deubiquitination; protein K63-linked deubiquitination; proteolysis; response to lipopolysaccharide; ubiquitin-specific protease activity,PF02338;,,,,,,,,,OTUD5_RAT,Rattus norvegicus (Rat),protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; response to lipopolysaccharide [GO:0032496] comp100581_c0_seq1,440,46.3636,0.81035235,20,54,,1.00E-61,O35099,Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),GO:0005524; GO:0007254; GO:0004709; GO:0000187; GO:0070301; GO:0008656; GO:0005783; GO:0045087; GO:0008631; GO:0000287; GO:0043065; GO:0042803,ATP binding; JNK cascade; MAP kinase kinase kinase activity; activation of MAPK activity; cellular response to hydrogen peroxide; cysteine-type endopeptidase activator activity involved in apoptotic process; endoplasmic reticulum; innate immune response; intrinsic apoptotic signaling pathway in response to oxidative stress; magnesium ion binding; positive regulation of apoptotic process; protein homodimerization activity,PF13281;PF00069;,2.00E-51,CHOYP_ASK1.1.2,,,,,,,M3K5_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931] comp100599_c0_seq1,305,42.9508,0.58286341,9,36,,4.00E-14,P22629,Streptavidin,Streptavidin,GO:0005576,extracellular region,PF01382;,,,5.00E-18,ruditapes_c9154,,,,,SAV_STRAV,Streptomyces avidinii, comp100629_c0_seq1,246,44.7154,0.81762357,7,0,,2.00E-20,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,6.00E-24,CHOYP_DYH2.1.1,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp10062_c0_seq1,312,47.1154,0.79847759,4,4,,6.00E-37,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,2.00E-26,CHOYP_MVP.1.1,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp100646_c0_seq1,466,56.0086,1.18207514,0,9,,4.00E-89,Q6A8N5,Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-),Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-),GO:0016021; GO:0042158; GO:0008961; GO:0005886; GO:0009249,integral to membrane; lipoprotein biosynthetic process; phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity; plasma membrane; protein lipoylation,PF01790;,,,,,,,,,LGT_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),lipoprotein biosynthetic process [GO:0042158]; protein lipoylation [GO:0009249] comp100646_c0_seq2,393,54.9618,1.1839019,0,0,,4.00E-12,Q834C0,Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-),Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-),GO:0016021; GO:0042158; GO:0008961; GO:0005886; GO:0009249,integral to membrane; lipoprotein biosynthetic process; phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity; plasma membrane; protein lipoylation,PF01790;,,,,,,,,,LGT_ENTFA,Enterococcus faecalis (strain ATCC 700802 / V583),lipoprotein biosynthetic process [GO:0042158]; protein lipoylation [GO:0009249] comp100661_c1_seq1,720,41.3889,0.5521928,14,95,,2.00E-131,Q8BPB0,MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A),MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A),GO:0005737; GO:0019209; GO:0019900; GO:0046872; GO:0005634; GO:0046777,cytoplasm; kinase activator activity; kinase binding; metal ion binding; nucleus; protein autophosphorylation,PF03637;,2.00E-155,CHOYP_MOB1.1.1,,,,,,,MOB1B_MOUSE,Mus musculus (Mouse),hippo signaling [GO:0035329]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952] comp100680_c0_seq1,798,38.9724,0.92868556,30,72,,4.00E-22,Q80TE4,Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),GO:0005096; GO:0043547; GO:0051056,GTPase activator activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction,PF02145;PF11881;,,,,,,,,,SI1L2_MOUSE,Mus musculus (Mouse),regulation of small GTPase mediated signal transduction [GO:0051056] comp100688_c2_seq1,336,44.0476,0.50149254,5,0,,5.00E-14,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp10068_c0_seq1,230,40.8696,0.73501389,5,0,,1.00E-10,Q803R5,Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),GO:0006370; GO:0097309; GO:0004483; GO:0003676; GO:0005634,7-methylguanosine mRNA capping; cap1 mRNA methylation; mRNA (nucleoside-2'-O-)-methyltransferase activity; nucleic acid binding; nucleus,PF01728;PF01585;PF00397;,,,,,,,,,MTR1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009] comp100707_c0_seq1,283,49.47,0.46405808,3,11,,4.00E-44,Q92609,TBC1 domain family member 5,TBC1 domain family member 5,GO:0005097; GO:0032851; GO:0030904,Rab GTPase activator activity; positive regulation of Rab GTPase activity; retromer complex,PF00566;,4.00E-52,CHOYP_LOC101078318.1.1,,,,,,,TBCD5_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of autophagy [GO:0010508]; positive regulation of receptor internalization [GO:0002092]; regulation of vesicle fusion [GO:0031338]; response to starvation [GO:0042594]; retrograde transport, endosome to Golgi [GO:0042147]" comp100709_c3_seq1,544,37.8676,0.76422534,0,66,,5.00E-08,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,2.00E-28,CHOYP_LOC659713.1.1,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp100725_c0_seq3,1068,40.3558,0.89855245,11,66,,7.00E-32,P86982,Insoluble matrix shell protein 1 (IMSP1) (Fragment),Insoluble matrix shell protein 1 (IMSP1) (Fragment),GO:0005576,extracellular region,,,,,,,,,,IMSP1_VENPH,Ruditapes philippinarum (Japanese littleneck clam) (Venerupis philippinarum), comp100732_c0_seq2,503,33.2008,0.59155163,4,38,,7.00E-25,Q6IV77,Tafazzin,Tafazzin,GO:0016021; GO:0016746,"integral to membrane; transferase activity, transferring acyl groups",PF01553;,,,,,,,,,TAZ_MACMU,Macaca mulatta (Rhesus macaque),cardiolipin acyl-chain remodeling [GO:0035965]; heart development [GO:0007507]; inner mitochondrial membrane organization [GO:0007007] comp100741_c0_seq1,813,42.6814,0.35188933,22,46,,2.00E-104,Q6IP59,Choline transporter-like protein 2 (Solute carrier family 44 member 2),Choline transporter-like protein 2 (Solute carrier family 44 member 2),GO:0016021; GO:0006810,integral to membrane; transport,PF04515;,4.00E-102,CHOYP_CTL2.1.2,,,,,,,CTL2_XENLA,Xenopus laevis (African clawed frog),transport [GO:0006810] comp100747_c0_seq2,1033,41.9167,0.39862963,17,35,,2.00E-50,Q5F479,Serine/threonine-protein kinase 11-interacting protein,Serine/threonine-protein kinase 11-interacting protein,GO:0005737,cytoplasm,PF15904;,,,,,,,,,S11IP_CHICK,Gallus gallus (Chicken), comp100759_c0_seq1,316,45.8861,1.24951981,6,3,,4.00E-12,A0R4R3,3-ketosteroid-9-alpha-monooxygenase oxygenase subunit (EC 1.14.13.142) (3-ketosteroid-9-alpha-hydroxylase oxygenase subunit) (Rieske-type oxygenase) (RO),3-ketosteroid-9-alpha-monooxygenase oxygenase subunit (EC 1.14.13.142) (3-ketosteroid-9-alpha-hydroxylase oxygenase subunit) (Rieske-type oxygenase) (RO),GO:0051537; GO:0036200; GO:0016042; GO:0046872; GO:0050292; GO:0006694,"2 iron, 2 sulfur cluster binding; 3-ketosteroid 9-alpha-monooxygenase activity; lipid catabolic process; metal ion binding; steroid 9-alpha-monooxygenase activity; steroid biosynthetic process",PF00355;,,,,,,,,,KSHA_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694] comp100759_c1_seq1,502,43.6255,0.84297301,7,53,,,,,,,,,2.00E-20,CHOYP_MGC154819.1.1,1.00E-21,ruditapes_c25669,,,,,,, comp100759_c2_seq1,507,47.5345,0.60022474,9,55,,1.00E-11,P71875,3-ketosteroid-9-alpha-monooxygenase oxygenase subunit (EC 1.14.13.142) (3-ketosteroid-9-alpha-hydroxylase oxygenase subunit) (Rieske-type oxygenase) (RO),3-ketosteroid-9-alpha-monooxygenase oxygenase subunit (EC 1.14.13.142) (3-ketosteroid-9-alpha-hydroxylase oxygenase subunit) (Rieske-type oxygenase) (RO),GO:0051537; GO:0036200; GO:0006707; GO:0008198; GO:0047086; GO:0009405; GO:0070207; GO:0070723; GO:0050292; GO:0006694,"2 iron, 2 sulfur cluster binding; 3-ketosteroid 9-alpha-monooxygenase activity; cholesterol catabolic process; ferrous iron binding; ketosteroid monooxygenase activity; pathogenesis; protein homotrimerization; response to cholesterol; steroid 9-alpha-monooxygenase activity; steroid biosynthetic process",PF00355;,,,,,,,,,KSHA_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; protein homotrimerization [GO:0070207]; response to cholesterol [GO:0070723]; steroid biosynthetic process [GO:0006694] comp100760_c0_seq1,213,52.5822,1.00979644,0,4,,1.00E-13,P35448,Thrombospondin-1,Thrombospondin-1,GO:0005509; GO:0007155; GO:0005576; GO:0008201; GO:0016529,calcium ion binding; cell adhesion; extracellular region; heparin binding; sarcoplasmic reticulum,PF12947;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP1_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; response to unfolded protein [GO:0006986] comp100789_c0_seq1,626,40.4153,0.79017215,0,98,,7.00E-11,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp100792_c0_seq1,779,44.801,0.85203715,30,8,,1.00E-74,Q8IWF2,FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),GO:0030433; GO:0005788; GO:0050660; GO:0016491,ER-associated protein catabolic process; endoplasmic reticulum lumen; flavin adenine dinucleotide binding; oxidoreductase activity,,,,,,,,,,FXRD2_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114] comp100792_c1_seq1,558,46.0573,1.15146377,22,13,,2.00E-06,A8GW75,Ferredoxin--NADP reductase (FNR) (Fd-NADP(+) reductase) (EC 1.18.1.2),Ferredoxin--NADP reductase (FNR) (Fd-NADP(+) reductase) (EC 1.18.1.2),GO:0050661; GO:0004324; GO:0050660,NADP binding; ferredoxin-NADP+ reductase activity; flavin adenine dinucleotide binding,PF07992;,,,,,,,,,FENR_RICB8,Rickettsia bellii (strain OSU 85-389), comp100817_c0_seq1,230,40.4348,0.22759051,3,28,,7.00E-06,Q9NNW5,WD repeat-containing protein 6,WD repeat-containing protein 6,GO:0007050; GO:0005737; GO:0010507; GO:0008285; GO:0043234,cell cycle arrest; cytoplasm; negative regulation of autophagy; negative regulation of cell proliferation; protein complex,PF00400;,,,,,,,,,WDR6_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; negative regulation of autophagy [GO:0010507]; negative regulation of cell proliferation [GO:0008285] comp100839_c0_seq1,466,40.5579,0.96732321,19,8,,2.00E-64,Q7TSH2,Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,,,,,,,,,KPBB_MOUSE,Mus musculus (Mouse),glycogen metabolic process [GO:0005977] comp100839_c1_seq1,399,46.8672,0.46232375,0,6,,,,,,,,,2.00E-51,CHOYP_KPBB.2.2,,,,,,,,, comp100874_c0_seq1,488,46.3115,0.42125637,12,40,,9.00E-30,O08912,Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form],Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form],GO:0032580; GO:0005576; GO:0016021; GO:0030145; GO:0048471; GO:0004653; GO:0006493; GO:0018242; GO:0018243,Golgi cisterna membrane; extracellular region; integral to membrane; manganese ion binding; perinuclear region of cytoplasm; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine,PF00535;PF00652;,1.00E-18,CHOYP_GLT13.2.2,,,,,,,GALT1_MOUSE,Mus musculus (Mouse),protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] comp100892_c0_seq1,212,59.434,1.17713145,0,8,,4.00E-43,Q6A9R1,Protein MraZ,Transcriptional regulator MraZ,,,PF02381;,,,,,,,,,MRAZ_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"transcription, DNA-templated [GO:0006351]" comp100892_c1_seq1,229,59.3886,1.06115057,0,0,,4.00E-17,A1SL89,Protein MraZ,Transcriptional regulator MraZ,,,PF02381;,,,,,,,,,MRAZ_NOCSJ,Nocardioides sp. (strain ATCC BAA-499 / JS614),"transcription, DNA-templated [GO:0006351]" comp100903_c0_seq2,776,42.9124,0.59764952,8,9,,3.00E-56,Q9UPR0,Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2),Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2),GO:0005509; GO:0005737; GO:0035556; GO:0006629; GO:0004435; GO:0005543; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid metabolic process; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF09279;PF16457;PF00388;PF00387;,5.00E-88,CHOYP_PLCL2.1.1,,,,,,,PLCL2_HUMAN,Homo sapiens (Human),"B-1a B cell differentiation [GO:0002337]; B cell proliferation involved in immune response [GO:0002322]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; positive regulation of receptor binding [GO:1900122]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of synaptic transmission, GABAergic [GO:0032228]" comp100905_c0_seq1,381,50.1312,0.39912046,15,0,,3.00E-32,Q9UGM3,Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein),Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein),GO:0048306; GO:0051607; GO:0030855; GO:0005576; GO:0019898; GO:0043152; GO:0045087; GO:0001833; GO:0019048; GO:0030670; GO:0030858; GO:0015031; GO:0005578; GO:0005044; GO:0008329; GO:0035375; GO:0042589,calcium-dependent protein binding; defense response to virus; epithelial cell differentiation; extracellular region; extrinsic to membrane; induction of bacterial agglutination; innate immune response; inner cell mass cell proliferation; modulation by virus of host morphology or physiology; phagocytic vesicle membrane; positive regulation of epithelial cell differentiation; protein transport; proteinaceous extracellular matrix; scavenger receptor activity; signaling pattern recognition receptor activity; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,,,,,,,,,DMBT1_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]; viral process [GO:0016032] comp100905_c2_seq1,240,47.5,0.54773678,11,0,,2.00E-09,Q60754,Macrophage receptor MARCO (Macrophage receptor with collagenous structure),Macrophage receptor MARCO (Macrophage receptor with collagenous structure),GO:0043277; GO:0005581; GO:0045087; GO:0016021; GO:0005886; GO:0005044,apoptotic cell clearance; collagen; innate immune response; integral to membrane; plasma membrane; scavenger receptor activity,PF01391;PF00530;,,,,,,,,,MARCO_MOUSE,Mus musculus (Mouse),apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898] comp100913_c0_seq1,261,65.1341,1.06104057,0,8,,1.00E-16,Q8L7W8,"Alpha-L-fucosidase 2 (EC 3.2.1.51) (Alpha-1,2-fucosidase 2) (Alpha-L-fucoside fucohydrolase 2)","Alpha-L-fucosidase 2 (EC 3.2.1.51) (Alpha-1,2-fucosidase 2) (Alpha-L-fucosidase 95A) (AtFuc95A) (Alpha-L-fucoside fucohydrolase 2) (Protein ALTERED XYLOGLUCAN 8)",GO:0047513; GO:0048046,"1,2-alpha-L-fucosidase activity; apoplast",PF14498;,,,,,,,,,FUCO2_ARATH,Arabidopsis thaliana (Mouse-ear cress),metabolic process [GO:0008152] comp100920_c0_seq1,391,62.1483,1.09542701,2,7,,1.00E-19,P42195,HTH-type transcriptional regulator PecS,HTH-type transcriptional regulator PecS,GO:0003677; GO:0005737; GO:0003700; GO:0006351,"DNA binding; cytoplasm; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01047;,,,,,,,,,PECS_DICD3,Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)),"transcription, DNA-templated [GO:0006351]" comp100921_c0_seq1,423,42.5532,0.91892405,2,67,,3.00E-37,P15387,Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (Voltage-gated potassium channel subunit Kv2.1),Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (Voltage-gated potassium channel subunit Kv2.1),GO:0005251; GO:0030425; GO:0032590; GO:0032809; GO:0015271; GO:0045211; GO:0051260; GO:0051259; GO:0008076,delayed rectifier potassium channel activity; dendrite; dendrite membrane; neuronal cell body membrane; outward rectifier potassium channel activity; postsynaptic membrane; protein homooligomerization; protein oligomerization; voltage-gated potassium channel complex,PF02214;PF00520;PF03521;,3.00E-19,CHOYP_KCNC4.2.5,,,,,,,KCNB1_RAT,Rattus norvegicus (Rat),action potential [GO:0001508]; cellular response to glucose stimulus [GO:0071333]; cellular response to nutrient levels [GO:0031669]; glucose homeostasis [GO:0042593]; glutamate receptor signaling pathway [GO:0007215]; negative regulation of insulin secretion [GO:0046676]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of catecholamine secretion [GO:0033605]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of norepinephrine secretion [GO:0010701]; positive regulation of protein targeting to membrane [GO:0090314]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein oligomerization [GO:0051259]; protein targeting to plasma membrane [GO:0072661]; regulation of action potential [GO:0098900]; regulation of motor neuron apoptotic process [GO:2000671]; vesicle docking involved in exocytosis [GO:0006904] comp100926_c0_seq1,605,46.9421,0.60406864,19,70,,3.00E-58,Q9WTQ1,Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu),Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu),GO:0005524; GO:0005794; GO:0007030; GO:0048193; GO:0001525; GO:0006915; GO:0005938; GO:0005911; GO:0034599; GO:0035924; GO:0005829; GO:0006954; GO:0045087; GO:0007243; GO:0035556; GO:0046872; GO:0060548; GO:0005634; GO:0018105; GO:0005543; GO:0005886; GO:0032793; GO:0043123; GO:0051092; GO:0045766; GO:0043536; GO:0038033; GO:0010595; GO:0001938; GO:1901727; GO:0010976; GO:0045669; GO:0033138; GO:0045944; GO:0004697; GO:0004674; GO:0010837; GO:0005802,ATP binding; Golgi apparatus; Golgi organization; Golgi vesicle transport; angiogenesis; apoptotic process; cell cortex; cell-cell junction; cellular response to oxidative stress; cellular response to vascular endothelial growth factor stimulus; cytosol; inflammatory response; innate immune response; intracellular protein kinase cascade; intracellular signal transduction; metal ion binding; negative regulation of cell death; nucleus; peptidyl-serine phosphorylation; phospholipid binding; plasma membrane; positive regulation of CREB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of histone deacetylase activity; positive regulation of neuron projection development; positive regulation of osteoblast differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein kinase C activity; protein serine/threonine kinase activity; regulation of keratinocyte proliferation; trans-Golgi network,PF00130;PF00169;PF00069;,8.00E-72,CHOYP_KPCD3.1.1,,,,,,,KPCD1_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of cell death [GO:0060548]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; Ras protein signal transduction [GO:0007265]; regulation of keratinocyte proliferation [GO:0010837]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279] comp100929_c0_seq1,301,41.196,0.23873781,4,0,,,,,,,,,6.00E-13,CHOYP_BRAFLDRAFT_66489.1.1,,,,,,,,, comp100929_c1_seq1,497,34.8089,1.06581491,9,6,,2.00E-34,Q8VDX6,Transmembrane protein 5,Transmembrane protein 5,GO:0016021,integral to membrane,,,,,,,,,,TMEM5_MOUSE,Mus musculus (Mouse),protein O-linked mannosylation [GO:0035269] comp100934_c0_seq1,854,44.7307,0.33532276,11,9,,8.00E-30,P35555,Fibrillin-1,Fibrillin-1 [Cleaved into: Asprosin],GO:0005604; GO:0005509; GO:0030198; GO:0005201; GO:0005615; GO:0007507; GO:0001527; GO:0035582; GO:0035583; GO:0001501,basement membrane; calcium ion binding; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; heart development; microfibril; sequestering of BMP in extracellular matrix; sequestering of TGFbeta in extracellular matrix; skeletal system development,PF12662;PF07645;PF00683;,,,,,,,,,FBN1_HUMAN,Homo sapiens (Human),activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] comp100934_c0_seq2,368,39.9457,0.34732937,2,1,,1.00E-06,Q6UXH8,Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog),Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog),GO:0005509; GO:0005581; GO:0005518; GO:0031012; GO:0001946; GO:0002040; GO:0048845,calcium ion binding; collagen; collagen binding; extracellular matrix; lymphangiogenesis; sprouting angiogenesis; venous blood vessel morphogenesis,PF01391;PF07645;,,,,,,,,,CCBE1_HUMAN,Homo sapiens (Human),lymphangiogenesis [GO:0001946]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of lymphangiogenesis [GO:1901492]; positive regulation of protein processing [GO:0010954]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; sprouting angiogenesis [GO:0002040]; venous blood vessel morphogenesis [GO:0048845] comp100937_c0_seq1,228,40.7895,0.10741295,12,0,,7.00E-15,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp100963_c1_seq1,267,45.6929,0.43636976,5,34,,1.00E-26,B1AUE5,Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10),Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10),GO:0005779; GO:0016558; GO:0008270,integral to peroxisomal membrane; protein import into peroxisome matrix; zinc ion binding,PF04757;,,,,,,,,,PEX10_MOUSE,Mus musculus (Mouse),peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] comp100965_c0_seq1,220,45,0.45889652,3,0,,5.00E-07,A7TTL0,ATP-dependent RNA helicase CHL1 (EC 3.6.4.13) (Chromosome loss protein 1),ATP-dependent DNA helicase CHL1 (EC 3.6.4.12) (Chromosome loss protein 1),GO:0005524; GO:0004003; GO:0003677; GO:0007049; GO:0005634,ATP binding; ATP-dependent DNA helicase activity; DNA binding; cell cycle; nucleus,PF06733;PF13307;,,,,,,,,,CHL1_VANPO,Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus),DNA replication initiation [GO:0006270]; donor selection [GO:0007535]; establishment of sister chromatid cohesion [GO:0034085]; interstrand cross-link repair [GO:0036297]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of DNA recombination [GO:0045910] comp100965_c1_seq1,251,52.1912,0.35711479,3,22,,2.00E-32,Q9NZ71,Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like),Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0046872; GO:0005634; GO:0010569; GO:0000723,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; metal ion binding; nucleus; regulation of double-strand break repair via homologous recombination; telomere maintenance",PF06733;PF13307;,4.00E-26,CHOYP_RTEL1.1.1,,,,,,,RTEL1_HUMAN,Homo sapiens (Human),DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of t-circle formation [GO:1904430]; negative regulation of telomere maintenance in response to DNA damage [GO:1904506]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of telomeric loop disassembly [GO:1904535]; regulation of double-strand break repair via homologous recombination [GO:0010569]; replication fork processing [GO:0031297]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247]; telomeric loop disassembly [GO:0090657] comp100966_c0_seq1,510,51.1765,1.14506868,5,41,,5.00E-25,Q71MB6,Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),GO:0016323; GO:0030154; GO:0016021; GO:0006811; GO:0007275; GO:0007283; GO:0005215,basolateral plasma membrane; cell differentiation; integral to membrane; ion transport; multicellular organismal development; spermatogenesis; transporter activity,PF07648;PF03137;,,,,,,,,,SO4C1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; sodium-independent organic anion transport [GO:0043252]; spermatogenesis [GO:0007283]; transport [GO:0006810] comp100966_c2_seq1,300,46.3333,0.93867987,0,25,,7.00E-30,Q8K078,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0006811; GO:0005886; GO:0005215,integral to membrane; ion transport; plasma membrane; transporter activity,PF07648;PF03137;,8.00E-24,CHOYP_BRAFLDRAFT_134943.1.1,,,,,,,SO4A1_MOUSE,Mus musculus (Mouse),organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp100981_c0_seq1,860,32.907,0.47303031,19,91,,4.00E-11,P39770,Homeotic protein spalt-major,Homeotic protein spalt-major,GO:0003677; GO:0045466; GO:0045465; GO:0048098; GO:0046845; GO:0007427; GO:0008586; GO:0030539; GO:0008584; GO:0046872; GO:0048644; GO:0045892; GO:0035310; GO:0005634; GO:0007438; GO:0042659; GO:0007605; GO:0007525; GO:0035277; GO:0006351,"DNA binding; R7 cell differentiation; R8 cell differentiation; antennal joint development; branched duct epithelial cell fate determination, open tracheal system; epithelial cell migration, open tracheal system; imaginal disc-derived wing vein morphogenesis; male genitalia development; male gonad development; metal ion binding; muscle organ morphogenesis; negative regulation of transcription, DNA-dependent; notum cell fate specification; nucleus; oenocyte development; regulation of cell fate specification; sensory perception of sound; somatic muscle development; spiracle morphogenesis, open tracheal system; transcription, DNA-dependent",PF00096;,,,,,,,,,SALM_DROME,Drosophila melanogaster (Fruit fly),"antennal joint development [GO:0048098]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; epithelial cell migration, open tracheal system [GO:0007427]; glial cell development [GO:0021782]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; muscle organ morphogenesis [GO:0048644]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription, DNA-templated [GO:0045892]; notum cell fate specification [GO:0035310]; oenocyte development [GO:0007438]; open tracheal system development [GO:0007424]; R7 cell differentiation [GO:0045466]; R8 cell differentiation [GO:0045465]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell fate specification [GO:0042659]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; somatic muscle development [GO:0007525]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]" comp101048_c0_seq1,333,40.8408,0.87895529,0,24,,1.00E-12,Q86IC9,Probable caffeoyl-CoA O-methyltransferase 1 (EC 2.1.1.104) (O-methyltransferase 5),Probable caffeoyl-CoA O-methyltransferase 1 (EC 2.1.1.104) (O-methyltransferase 5),GO:0042409; GO:0046872,caffeoyl-CoA O-methyltransferase activity; metal ion binding,PF01596;,,,,,,,,,CAMT1_DICDI,Dictyostelium discoideum (Slime mold), comp101055_c1_seq1,312,47.1154,0.52439109,4,36,,5.00E-44,Q8R420,ATP-binding cassette sub-family A member 3,ATP-binding cassette sub-family A member 3,GO:0005524; GO:0006200; GO:0016887; GO:0097233; GO:0016021; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; alveolar lamellar body membrane; integral to membrane; plasma membrane; transport,PF00005;,1.00E-46,CHOYP_ABCA3.5.6,,,,,,,ABCA3_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810] comp101065_c0_seq1,659,47.041,0.49855333,2,10,,3.00E-65,Q923Q2,StAR-related lipid transfer protein 13 (START domain-containing protein 13) (StARD13),StAR-related lipid transfer protein 13 (START domain-containing protein 13) (StARD13),GO:0005096; GO:0007049; GO:0008289; GO:0005811; GO:0031966; GO:0043547; GO:0007165,GTPase activator activity; cell cycle; lipid binding; lipid particle; mitochondrial membrane; positive regulation of GTPase activity; signal transduction,PF00620;PF07647;PF01852;,7.00E-29,CHOYP_RHG07.1.1,,,,,,,STA13_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of sprouting angiogenesis [GO:1903671]; signal transduction [GO:0007165] comp101065_c0_seq2,672,46.7262,0.52234593,0,5,,1.00E-62,Q923Q2,StAR-related lipid transfer protein 13 (START domain-containing protein 13) (StARD13),StAR-related lipid transfer protein 13 (START domain-containing protein 13) (StARD13),GO:0005096; GO:0007049; GO:0008289; GO:0005811; GO:0031966; GO:0043547; GO:0007165,GTPase activator activity; cell cycle; lipid binding; lipid particle; mitochondrial membrane; positive regulation of GTPase activity; signal transduction,PF00620;PF07647;PF01852;,,,,,,,,,STA13_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of sprouting angiogenesis [GO:1903671]; signal transduction [GO:0007165] comp101070_c0_seq1,264,63.2576,1.19911223,1,8,,3.00E-07,A5UBC5,Ribosomal RNA small subunit methyltransferase C (EC 2.1.1.172) (16S rRNA m2G1207 methyltransferase) (rRNA (guanine-N(2)-)-methyltransferase RsmC),Ribosomal RNA small subunit methyltransferase C (EC 2.1.1.172) (16S rRNA m2G1207 methyltransferase) (rRNA (guanine-N(2)-)-methyltransferase RsmC),GO:0052914; GO:0005737; GO:0003676; GO:0031167,16S rRNA (guanine(1207)-N(2))-methyltransferase activity; cytoplasm; nucleic acid binding; rRNA methylation,PF05175;PF08468;,,,,,,,,,RSMC_HAEIE,Haemophilus influenzae (strain PittEE), comp101079_c0_seq1,613,44.3719,0.70690978,32,28,,1.00E-20,Q0VCP9,Coiled-coil domain-containing protein 149,Coiled-coil domain-containing protein 149,GO:0016021,integral to membrane,PF09789;,3.00E-39,CHOYP_LOC100344710.1.1,,,,,,,CC149_BOVIN,Bos taurus (Bovine), comp101083_c0_seq1,632,41.4557,0.59911419,1,111,,1.00E-36,Q8IWU5,Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-),Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-),GO:0005795; GO:0008449; GO:0004065; GO:0060348; GO:0005509; GO:0009986; GO:0002063; GO:0048706; GO:0005783; GO:0014846; GO:0005615; GO:0035860; GO:0032836; GO:0003094; GO:0030201; GO:0060384; GO:0040037; GO:0005886; GO:0030177; GO:0010575,Golgi stack; N-acetylglucosamine-6-sulfatase activity; arylsulfatase activity; bone development; calcium ion binding; cell surface; chondrocyte development; embryonic skeletal system development; endoplasmic reticulum; esophagus smooth muscle contraction; extracellular space; glial cell-derived neurotrophic factor receptor signaling pathway; glomerular basement membrane development; glomerular filtration; heparan sulfate proteoglycan metabolic process; innervation; negative regulation of fibroblast growth factor receptor signaling pathway; plasma membrane; positive regulation of Wnt receptor signaling pathway; positive regulation vascular endothelial growth factor production,PF12548;PF00884;,,,,,,,,,SULF2_HUMAN,Homo sapiens (Human),bone development [GO:0060348]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; liver regeneration [GO:0097421]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of hepatocyte proliferation [GO:2000345]; response to wounding [GO:0009611] comp101091_c0_seq1,662,48.9426,0.94919734,10,68,,6.00E-46,Q16832,"Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)","Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)",GO:0005524; GO:0031214; GO:0007155; GO:0035988; GO:0005518; GO:0030199; GO:0003416; GO:0005887; GO:0001503; GO:0090091; GO:0010763; GO:0048146; GO:0045669; GO:0045860; GO:0051091; GO:0046777; GO:0038062; GO:0030500,ATP binding; biomineral tissue development; cell adhesion; chondrocyte proliferation; collagen binding; collagen fibril organization; endochondral bone growth; integral to plasma membrane; ossification; positive regulation of extracellular matrix disassembly; positive regulation of fibroblast migration; positive regulation of fibroblast proliferation; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; positive regulation of sequence-specific DNA binding transcription factor activity; protein autophosphorylation; protein tyrosine kinase collagen receptor activity; regulation of bone mineralization,PF00754;PF07714;,3.00E-39,CHOYP_LOC100903889.1.1,,,,,,,DDR2_HUMAN,Homo sapiens (Human),biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; signal transduction [GO:0007165] comp101105_c0_seq1,385,50.9091,0.56557158,1,22,,2.00E-57,Q96AY4,Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0000922,cell division; cytoplasm; microtubule organizing center; midbody; mitosis; spindle pole,PF12770;PF13176;PF13181;,4.00E-48,CHOYP_TTC28.1.1,,,,,,,TTC28_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp101105_c1_seq1,369,40.1084,0.92732511,0,13,,1.00E-16,Q86YR5,G-protein-signaling modulator 1 (Activator of G-protein signaling 3),G-protein-signaling modulator 1 (Activator of G-protein signaling 3),GO:0005092; GO:0005794; GO:0000139; GO:0030154; GO:0005829; GO:0005789; GO:0007399; GO:0005634; GO:0005886; GO:0008277,GDP-dissociation inhibitor activity; Golgi apparatus; Golgi membrane; cell differentiation; cytosol; endoplasmic reticulum membrane; nervous system development; nucleus; plasma membrane; regulation of G-protein coupled receptor protein signaling pathway,PF02188;,,,,,,,,,GPSM1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp101111_c0_seq1,252,45.2381,0.6247012,9,1,,8.00E-31,Q8UVC3,Inversin,Inversin,GO:0016055; GO:0005737; GO:0005856; GO:0007275,Wnt receptor signaling pathway; cytoplasm; cytoskeleton; multicellular organismal development,PF12796;PF00612;,5.00E-44,CHOYP_INVS.5.6,,,,,,,INVS_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp101114_c0_seq1,323,46.7492,0.98182759,6,22,,,,,,,,,,,4.00E-20,ruditapes_c30186,,,,,,, comp101125_c0_seq1,755,48.3444,0.36324388,22,9,,2.00E-45,P51111,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0030424; GO:0007417; GO:0030136; GO:0005829; GO:0030425; GO:0051028; GO:2000117; GO:0043025; GO:0005634; GO:0048513; GO:0014069; GO:0008134,axon; central nervous system development; clathrin-coated vesicle; cytosol; dendrite; mRNA transport; negative regulation of cysteine-type endopeptidase activity; neuronal cell body; nucleus; organ development; postsynaptic density; transcription factor binding,PF12372;,2.00E-18,CHOYP_HD.1.1,,,,,,,HD_RAT,Rattus norvegicus (Rat),animal organ development [GO:0048513]; central nervous system development [GO:0007417]; mRNA transport [GO:0051028]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; regulation of intracellular mRNA localization [GO:1904580] comp101127_c0_seq2,824,41.3835,0.76863467,13,58,,2.00E-24,Q9QUK4,Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2),Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2),GO:0005524; GO:0072557; GO:0006915; GO:0071391; GO:0042742; GO:0016045; GO:0006954; GO:0045087; GO:0046872; GO:0070269,ATP binding; IPAF inflammasome complex; apoptotic process; cellular response to estrogen stimulus; defense response to bacterium; detection of bacterium; inflammatory response; innate immune response; metal ion binding; pyroptosis,PF00653;,,,,,,,,,BIR1B_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cellular response to estrogen stimulus [GO:0071391]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; pyroptosis [GO:0070269]; regulation of signal transduction [GO:0009966] comp101135_c1_seq1,272,43.75,0.62223063,19,15,,9.00E-16,Q9I9B9,Choline transporter-like protein 1 (Solute carrier family 44 member 1),Choline transporter-like protein 1 (Solute carrier family 44 member 1),GO:0016021; GO:0006810,integral to membrane; transport,PF04515;,,,,,,,,,CTL1_TORMA,Torpedo marmorata (Marbled electric ray),transport [GO:0006810] comp101136_c0_seq1,220,39.5455,1.17181636,4,40,,3.00E-13,Q9BWW7,Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (hScrt),Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (hScrt),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,SCRT1_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp101136_c1_seq1,379,41.4248,1.11546765,9,38,,5.00E-23,Q68DY1,Zinc finger protein 626,Zinc finger protein 626,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN626_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp101146_c0_seq2,693,42.7128,0.507311,4,12,,9.00E-36,Q14123,"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)","Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)",GO:0007202; GO:0004117; GO:0005829; GO:0007173; GO:0008543; GO:0045087; GO:0046872; GO:0048011,activation of phospholipase C activity; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; metal ion binding; neurotrophin TRK receptor signaling pathway,PF00233;PF08499;,5.00E-25,CHOYP_PDE4D.1.1,,,,,,,PDE1C_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp101146_c1_seq1,1207,42.2535,0.51360579,53,154,,4.00E-97,Q08499,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43)","cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43)",GO:0004115; GO:0050852; GO:0086024; GO:0007568; GO:0031698; GO:0030552; GO:0006198; GO:0019933; GO:0034704; GO:0071320; GO:0071872; GO:0071222; GO:0005829; GO:0008144; GO:0019899; GO:0061028; GO:0044325; GO:0016020; GO:0046872; GO:0005815; GO:0035264; GO:0045822; GO:0033137; GO:1901898; GO:0030593; GO:0032729; GO:0032743; GO:0032754; GO:0086004; GO:1901844; GO:0010469; GO:0010880; GO:0060314; GO:0006939,"3',5'-cyclic-AMP phosphodiesterase activity; T cell receptor signaling pathway; adrenergic receptor signaling pathway involved in positive regulation of heart rate; aging; beta-2 adrenergic receptor binding; cAMP binding; cAMP catabolic process; cAMP-mediated signaling; calcium channel complex; cellular response to cAMP; cellular response to epinephrine stimulus; cellular response to lipopolysaccharide; cytosol; drug binding; enzyme binding; establishment of endothelial barrier; ion channel binding; membrane; metal ion binding; microtubule organizing center; multicellular organism growth; negative regulation of heart contraction; negative regulation of peptidyl-serine phosphorylation; negative regulation of relaxation of cardiac muscle; neutrophil chemotaxis; positive regulation of interferon-gamma production; positive regulation of interleukin-2 production; positive regulation of interleukin-5 production; regulation of cardiac muscle cell contraction; regulation of cell communication by electrical coupling involved in cardiac conduction; regulation of receptor activity; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; regulation of ryanodine-sensitive calcium-release channel activity; smooth muscle contraction",PF00233;,7.00E-89,CHOYP_LOC100874620.1.1,,,,,,,PDE4D_HUMAN,Homo sapiens (Human),adrenergic receptor signaling pathway [GO:0071875]; adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; multicellular organism growth [GO:0035264]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cAMP metabolic process [GO:0030814]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of receptor activity [GO:0010469]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852] comp101158_c1_seq2,219,47.032,0.41794184,7,9,,1.00E-06,Q9QXJ1,Amyloid beta A4 precursor protein-binding family B member 1 (Protein Fe65),Amyloid beta A4 precursor protein-binding family B member 1 (Protein Fe65),GO:0030048; GO:0006915; GO:0007411; GO:0001540; GO:0007050; GO:0005737; GO:0006302; GO:0030198; GO:0030426; GO:0043967; GO:0035035; GO:0030027; GO:0030308; GO:0045665; GO:0050760; GO:0001764; GO:0016607; GO:0005634; GO:0005886; GO:0045739; GO:0043065; GO:0045944; GO:0050821; GO:0006355; GO:0045202; GO:0008134; GO:0006351; GO:0008542,"actin filament-based movement; apoptotic process; axon guidance; beta-amyloid binding; cell cycle arrest; cytoplasm; double-strand break repair; extracellular matrix organization; growth cone; histone H4 acetylation; histone acetyltransferase binding; lamellipodium; negative regulation of cell growth; negative regulation of neuron differentiation; negative regulation of thymidylate synthase biosynthetic process; neuron migration; nuclear speck; nucleus; plasma membrane; positive regulation of DNA repair; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; protein stabilization; regulation of transcription, DNA-dependent; synapse; transcription factor binding; transcription, DNA-dependent; visual learning",PF00640;,,,,,,,,,APBB1_MOUSE,Mus musculus (Mouse),"actin filament-based movement [GO:0030048]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; extracellular matrix organization [GO:0030198]; histone H4 acetylation [GO:0043967]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thymidylate synthase biosynthetic process [GO:0050760]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA repair [GO:0045739]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]" comp101173_c0_seq1,581,45.0947,0.56147287,5,67,,9.00E-54,Q3UPY5,Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),GO:0004565; GO:0005975; GO:0005576,beta-galactosidase activity; carbohydrate metabolic process; extracellular region,PF01301;,9.00E-14,CHOYP_GLBL2.1.2,,,,,,,GLBL2_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975] comp101177_c0_seq1,220,74.0909,1.13644211,0,2,,5.00E-06,Q9FIZ7,5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Protein OXOPROLINASE 1) (Pyroglutamase),5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Protein OXOPROLINASE 1) (Pyroglutamase),GO:0017168; GO:0005524; GO:0005829; GO:0006751; GO:0009506,5-oxoprolinase (ATP-hydrolyzing) activity; ATP binding; cytosol; glutathione catabolic process; plasmodesma,PF05378;PF01968;PF02538;,,,,,,,,,OPLA_ARATH,Arabidopsis thaliana (Mouse-ear cress),glutathione catabolic process [GO:0006751] comp101179_c0_seq1,618,41.4239,0.71788017,13,47,,2.00E-10,B7ZRM8,MDS1 and EVI1 complex locus protein EVI1-B (Ecotropic virus integration site 1 protein homolog-B),MDS1 and EVI1 complex locus protein EVI1-B (Ecotropic virus integration site 1 protein homolog-B),GO:0003677; GO:0046872; GO:0016607; GO:0039013; GO:0039022; GO:0072196; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nuclear speck; pronephric distal tubule morphogenesis; pronephric duct development; proximal/distal pattern formation involved in pronephric nephron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,EVI1B_XENLA,Xenopus laevis (African clawed frog),"pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp101180_c1_seq1,417,36.6906,0.35898523,7,9,,1.00E-24,O64411,Polyamine oxidase (EC 1.5.3.14) (EC 1.5.3.15),Polyamine oxidase (EC 1.5.3.14) (EC 1.5.3.15),GO:0052898; GO:0052893; GO:0052897; GO:0052896; GO:0052900,"N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity; spermidine oxidase (propane-1,3-diamine-forming) activity; spermine oxidase (propane-1,3-diamine-forming) activity",PF01593;,,,,,,,,,PAO_MAIZE,Zea mays (Maize), comp10118_c0_seq1,203,50.2463,0.76342809,2,5,,2.00E-28,Q12852,Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase),Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase),GO:0005524; GO:0007254; GO:0004709; GO:0005829; GO:0030426; GO:0016572; GO:0018105; GO:0018107; GO:0005886; GO:0046777; GO:0042803; GO:0004674,ATP binding; JNK cascade; MAP kinase kinase kinase activity; cytosol; growth cone; histone phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; plasma membrane; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity,PF07714;,2.00E-29,CHOYP_LOC590385.1.1,,,,,,,M3K12_HUMAN,Homo sapiens (Human),histone phosphorylation [GO:0016572]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of motor neuron apoptotic process [GO:2000672]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp101192_c1_seq1,558,40.1434,0.42581601,28,24,,2.00E-40,Q66IZ7,Nuclear distribution protein nudE-like 1-B,Nuclear distribution protein nudE-like 1-B,GO:0005737; GO:0005874; GO:0005815; GO:0005819; GO:0006810,cytoplasm; microtubule; microtubule organizing center; spindle; transport,PF04880;,1.00E-49,CHOYP_NDL1A.1.1,,,,,,,NDL1B_XENLA,Xenopus laevis (African clawed frog),transport [GO:0006810] comp101197_c0_seq1,208,46.1538,0.55983437,2,8,,3.00E-18,Q9VCY8,ADIPOR-like receptor CG5315,Adiponectin receptor protein,GO:0019395; GO:0042593; GO:0042562; GO:0009755; GO:0016021; GO:0032024; GO:0070328,fatty acid oxidation; glucose homeostasis; hormone binding; hormone-mediated signaling pathway; integral to membrane; positive regulation of insulin secretion; triglyceride homeostasis,PF03006;,,,,,,,,,ADRL_DROME,Drosophila melanogaster (Fruit fly),adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328] comp101197_c1_seq1,671,43.2191,0.44851358,34,66,,9.00E-99,Q9VCY8,ADIPOR-like receptor CG5315,Adiponectin receptor protein,GO:0019395; GO:0042593; GO:0042562; GO:0009755; GO:0016021; GO:0032024; GO:0070328,fatty acid oxidation; glucose homeostasis; hormone binding; hormone-mediated signaling pathway; integral to membrane; positive regulation of insulin secretion; triglyceride homeostasis,PF03006;,1.00E-94,CHOYP_DGRI_GH17396.1.1,,,,,,,ADRL_DROME,Drosophila melanogaster (Fruit fly),adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328] comp101203_c0_seq2,604,44.3709,0.44217808,4,26,,2.00E-73,Q922Q5,Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3),Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3),GO:0000139; GO:0016021; GO:0005739; GO:0055085,Golgi membrane; integral to membrane; mitochondrion; transmembrane transport,PF08449;,,,,,,,,,S35B3_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp101242_c0_seq1,470,40.2128,0.58057188,20,18,,,,,,,,,,,2.00E-12,ruditapes_c21092,,,,,,, comp101254_c0_seq2,470,45.7447,1.06026454,3,30,,1.00E-20,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp101271_c2_seq1,951,37.7497,0.60036643,46,40,,3.00E-77,Q28293,Potassium voltage-gated channel subfamily A member 2 (CSMK1) (Voltage-gated potassium channel subunit Kv1.2),Potassium voltage-gated channel subfamily A member 2 (CSMK1) (Voltage-gated potassium channel subunit Kv1.2),GO:0051260; GO:0005249; GO:0008076,protein homooligomerization; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF02214;PF00520;,0,CHOYP_LOC100533422.1.1,,,,,,,KCNA2_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of dopamine secretion [GO:0014059]; sensory perception of pain [GO:0019233] comp101287_c0_seq1,592,40.8784,0.563525,20,48,,2.00E-30,Q7TMF2,3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1),3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1),GO:0008408; GO:0005737; GO:0031047; GO:0071204; GO:0071207; GO:0046872; GO:0005730; GO:0031125; GO:0019843; GO:0043022,3'-5' exonuclease activity; cytoplasm; gene silencing by RNA; histone pre-mRNA 3'end processing complex; histone pre-mRNA stem-loop binding; metal ion binding; nucleolus; rRNA 3'-end processing; rRNA binding; ribosome binding,PF00929;PF02037;,4.00E-19,CHOYP_ERI1.1.1,,,,,,,ERI1_MOUSE,Mus musculus (Mouse),"exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; gene silencing by RNA [GO:0031047]; rRNA 3'-end processing [GO:0031125]" comp101296_c0_seq1,402,40.2985,0.13082373,9,14,,5.00E-06,C1GB49,Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog),Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog),GO:0051301; GO:0006928; GO:0005737; GO:0000132; GO:0005874; GO:0005875; GO:0007067; GO:0000922; GO:0006810,cell division; cellular component movement; cytoplasm; establishment of mitotic spindle orientation; microtubule; microtubule associated complex; mitosis; spindle pole; transport,PF00400;,,,,,,,,,LIS1_PARBD,Paracoccidioides brasiliensis (strain Pb18),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic nuclear division [GO:0007067]; transport [GO:0006810] comp101296_c1_seq1,602,40.3654,0.24730075,2,0,,8.00E-100,Q803V5,"Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog)","Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog)",GO:0005737,cytoplasm,PF00400;,5.00E-87,CHOYP_LOC100376733.1.1,,,,,,,LST8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp101296_c1_seq2,652,40.3374,0.26715434,0,1,,3.00E-107,Q803V5,"Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog)","Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog)",GO:0005737,cytoplasm,PF00400;,,,8.00E-45,ruditapes_c22482,,,,,LST8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp101297_c1_seq1,290,45.5172,0.80834295,2,34,,,,,,,,,5.00E-14,CHOYP_MBCDH18.1.1,,,,,,,,, comp101306_c0_seq1,239,43.9331,0.88890445,0,35,,3.00E-08,Q90953,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp101348_c0_seq1,398,46.7337,0.74233027,19,8,,2.00E-26,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp101350_c0_seq1,443,62.754,1.18580412,4,17,,5.00E-49,A4FDS0,Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase),Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase),GO:0005524; GO:0006526; GO:0004055; GO:0005737,ATP binding; arginine biosynthetic process; argininosuccinate synthase activity; cytoplasm,PF00764;,,,,,,,,,ASSY_SACEN,Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338),arginine biosynthetic process [GO:0006526] comp101354_c0_seq1,375,42.4,0.41924478,11,28,,3.00E-24,B0S5N4,Plexin A3,Plexin A3,GO:0048675; GO:0048755; GO:0060272; GO:0016021; GO:0005622; GO:0008045; GO:0005886; GO:0004872; GO:0048696; GO:0007165,axon extension; branching morphogenesis of a nerve; embryonic skeletal joint morphogenesis; integral to membrane; intracellular; motor neuron axon guidance; plasma membrane; receptor activity; regulation of collateral sprouting in absence of injury; signal transduction,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp101356_c0_seq1,2120,40,0.63851366,62,201,,0,Q5IGR8,Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a),Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a),GO:0050509; GO:0050508; GO:0015012; GO:0030176; GO:0006486,N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to endoplasmic reticulum membrane; protein glycosylation,PF03016;PF09258;,2.00E-111,CHOYP_EXT1A.1.1,3.00E-82,ruditapes_c26999,,,,,EXT1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486] comp101375_c0_seq1,718,43.8719,0.56019956,39,45,,8.00E-46,Q5REG4,Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3),Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3),GO:0007219; GO:0005737; GO:0016874; GO:0016567; GO:0008270,Notch signaling pathway; cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,,1.00E-14,CHOYP_DTX3L.4.4,,,,,,,DTX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] comp101384_c0_seq1,545,34.3119,1.06420904,6,19,,6.00E-13,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp101385_c0_seq1,252,44.0476,0.90534932,1,30,,3.00E-13,A7UA95,Ras-associating and dilute domain-containing protein,Ras-associating and dilute domain-containing protein,GO:0007155; GO:0007275; GO:0007165,cell adhesion; multicellular organismal development; signal transduction,PF01843;PF00595;PF00788;,,,,,,,,,RADIL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; neural crest cell migration [GO:0001755]; signal transduction [GO:0007165] comp101400_c1_seq1,783,44.4444,0.62445343,7,82,,8.00E-84,Q28DB5,Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2),Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2),GO:0006103; GO:0042853; GO:0042851; GO:0004021; GO:0009058; GO:0030170,2-oxoglutarate metabolic process; L-alanine catabolic process; L-alanine metabolic process; L-alanine:2-oxoglutarate aminotransferase activity; biosynthetic process; pyridoxal phosphate binding,PF00155;,2.00E-54,CHOYP_LOC100164899.1.1,,,,,,,ALAT2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] comp101411_c0_seq1,224,55.3571,1.63178111,0,8,,1.00E-12,O68956,Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase),Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase),GO:0030246; GO:0016051; GO:0005737; GO:0006541; GO:0004360,carbohydrate binding; carbohydrate biosynthetic process; cytoplasm; glutamine metabolic process; glutamine-fructose-6-phosphate transaminase (isomerizing) activity,PF01380;,,,,,,,,,GLMS_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),carbohydrate derivative biosynthetic process [GO:1901137]; carbohydrate metabolic process [GO:0005975]; glutamine metabolic process [GO:0006541] comp101420_c0_seq1,406,34.2365,0.17993036,3,11,,1.00E-09,Q5HYI8,Rab-like protein 3,Rab-like protein 3,GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF08477;,,,,,,,,,RABL3_HUMAN,Homo sapiens (Human),small GTPase mediated signal transduction [GO:0007264] comp101422_c0_seq1,798,44.1103,0.51695216,28,75,,1.00E-35,Q9UKT8,F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6),F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6),GO:0005737; GO:0006508; GO:0004842,cytoplasm; proteolysis; ubiquitin-protein ligase activity,PF12937;PF00400;,,,,,,,,,FBXW2_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; proteolysis [GO:0006508] comp101435_c0_seq1,812,39.1626,0.55640181,22,57,,2.00E-45,Q502J0,Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 1),Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 1),GO:0003841; GO:0047184; GO:0047192; GO:0000139; GO:0005509; GO:0005789; GO:0016021; GO:0005811; GO:0008654,1-acylglycerol-3-phosphate O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 1-alkylglycerophosphocholine O-acetyltransferase activity; Golgi membrane; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; lipid particle; phospholipid biosynthetic process,PF01553;PF13202;PF13499;,1.00E-19,CHOYP_PCAT2.2.2,,,,,,,PCAT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phospholipid biosynthetic process [GO:0008654] comp10147_c0_seq1,266,49.2481,1.18308575,9,0,,8.00E-17,O35516,Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],GO:0007219; GO:0060413; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0061073; GO:0005829; GO:0030326; GO:0005576; GO:0072104; GO:0072015; GO:0001947; GO:0006959; GO:0001701; GO:0002437; GO:0005887; GO:0072602; GO:0070986; GO:0002011; GO:0008285; GO:0000122; GO:0005654; GO:0060674; GO:0030513; GO:0046579; GO:0043065; GO:0008284; GO:0045672; GO:0072014; GO:0006351; GO:0042060,"Notch signaling pathway; atrial septum morphogenesis; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; ciliary body morphogenesis; cytosol; embryonic limb morphogenesis; extracellular region; glomerular capillary formation; glomerular visceral epithelial cell development; heart looping; humoral immune response; in utero embryonic development; inflammatory response to antigenic stimulus; integral to plasma membrane; interleukin-4 secretion; left/right axis specification; morphogenesis of an epithelial sheet; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; placenta blood vessel development; positive regulation of BMP signaling pathway; positive regulation of Ras protein signal transduction; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of osteoclast differentiation; proximal tubule development; transcription, DNA-dependent; wound healing",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_MOUSE,Mus musculus (Mouse),"atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]" comp101490_c0_seq1,914,49.8906,0.99651209,32,75,,4.00E-73,Q5ZIJ9,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB2_CHICK,Gallus gallus (Chicken),Notch signaling pathway [GO:0007219] comp101491_c0_seq1,244,59.0164,1.18176787,0,15,,1.00E-33,P66844,Signal recognition particle protein (Fifty-four homolog),,GO:0008312; GO:0005525; GO:0006184; GO:0003924; GO:0006614; GO:0005618; GO:0040007; GO:0005886; GO:0005786,"7S RNA binding; GTP binding; GTP catabolic process; GTPase activity; SRP-dependent cotranslational protein targeting to membrane; cell wall; growth; plasma membrane; signal recognition particle, endoplasmic reticulum targeting",,,,,,,,,,SRP54_MYCTU,, comp101509_c1_seq1,286,50.3497,0.73387994,4,36,,3.00E-08,Q8BZ64,Tectonic-1,Tectonic-1,GO:0036038; GO:0021956; GO:0060271; GO:0005737; GO:0021904; GO:0005615; GO:0001701; GO:0016020; GO:0005932; GO:0001841; GO:0008589; GO:0021523; GO:0021537,TCTN-B9D complex; central nervous system interneuron axonogenesis; cilium morphogenesis; cytoplasm; dorsal/ventral neural tube patterning; extracellular space; in utero embryonic development; membrane; microtubule basal body; neural tube formation; regulation of smoothened signaling pathway; somatic motor neuron differentiation; telencephalon development,PF07773;,,,,,,,,,TECT1_MOUSE,Mus musculus (Mouse),central nervous system interneuron axonogenesis [GO:0021956]; cilium morphogenesis [GO:0060271]; dorsal/ventral neural tube patterning [GO:0021904]; in utero embryonic development [GO:0001701]; neural tube formation [GO:0001841]; protein localization to ciliary transition zone [GO:1904491]; regulation of smoothened signaling pathway [GO:0008589]; somatic motor neuron differentiation [GO:0021523]; telencephalon development [GO:0021537] comp101515_c0_seq1,271,47.2325,1.33629921,0,25,,6.00E-35,Q32KR8,[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),GO:0003875; GO:0006464; GO:0000287; GO:0051725,ADP-ribosylarginine hydrolase activity; cellular protein modification process; magnesium ion binding; protein de-ADP-ribosylation,PF03747;,,,,,,,,,ADPRH_BOVIN,Bos taurus (Bovine),cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725] comp101526_c0_seq2,426,41.0798,0.39072111,0,0,,5.00E-62,Q8IW35,Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2),Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2),GO:0030030; GO:0005813; GO:0005737; GO:0005634,cell projection organization; centrosome; cytoplasm; nucleus,,,,,,,,,,CEP97_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018]; regulation of mitotic spindle assembly [GO:1901673] comp101526_c1_seq1,327,46.789,0.33954769,11,2,,7.00E-09,Q6DIQ3,Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),GO:0005634,nucleus,PF12799;,,,,,,,,,PP1R7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp101538_c0_seq1,578,34.7751,0.4123944,33,82,,4.00E-07,Q6AYK9,Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48),Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48),GO:0016573; GO:0004402; GO:0035064; GO:0005634; GO:0006355; GO:0003714; GO:0006351,"histone acetylation; histone acetyltransferase activity; methylated histone residue binding; nucleus; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF00385;PF00378;,,,,,,,,,CDYL_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp101540_c0_seq1,429,50.3497,0.6489737,15,3,,1.00E-49,Q6IDD9,Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog) (dSarm),Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog) (dSarm),GO:0030424; GO:0005737; GO:0045087; GO:0043005; GO:0043025; GO:1901214; GO:0007165,axon; cytoplasm; innate immune response; neuron projection; neuronal cell body; regulation of neuron death; signal transduction,PF07647;PF13676;,2.00E-20,CHOYP_AAEL_AAEL014931.1.1,,,,,,,SARM1_DROME,Drosophila melanogaster (Fruit fly),innate immune response [GO:0045087]; regulation of neuron death [GO:1901214]; response to axon injury [GO:0048678]; signal transduction [GO:0007165] comp101540_c1_seq1,434,43.0876,0.4357649,9,17,,7.00E-29,Q6SZW1,Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog),Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog),GO:0002756; GO:0030424; GO:0030054; GO:0005829; GO:0030425; GO:0045087; GO:0005874; GO:0005739; GO:0048814; GO:1901214; GO:0045202; GO:0034138; GO:0034142,MyD88-independent toll-like receptor signaling pathway; axon; cell junction; cytosol; dendrite; innate immune response; microtubule; mitochondrion; regulation of dendrite morphogenesis; regulation of neuron death; synapse; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway,PF07647;PF13676;,,,,,,,,,SARM1_HUMAN,Homo sapiens (Human),innate immune response [GO:0045087]; negative regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034128]; regulation of apoptotic process [GO:0042981]; regulation of dendrite morphogenesis [GO:0048814]; regulation of neuron death [GO:1901214]; response to glucose [GO:0009749]; signal transduction [GO:0007165] comp101596_c0_seq1,385,45.1948,0.10286545,14,34,,6.00E-08,Q9NUJ3,T-complex protein 11-like protein 1,T-complex protein 11-like protein 1,GO:0005874,microtubule,PF05794;,,,,,,,,,T11L1_HUMAN,Homo sapiens (Human), comp101610_c0_seq1,259,42.0849,0.09325821,9,2,,3.00E-19,Q9JIM3,Putative DNA repair and recombination protein RAD26-like (EC 3.6.4.-),DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0005737; GO:0005815; GO:0005634,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; cytoplasm; microtubule organizing center; nucleus,PF00271;PF00176;PF14773;,3.00E-21,CHOYP_LOC100014225.1.1,,,,,,,RAD26_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281] comp101610_c2_seq1,322,44.7205,0.37413488,10,9,,8.00E-19,Q5T890,Putative DNA repair and recombination protein RAD26-like (EC 3.6.4.-),DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0005737; GO:0005815; GO:0005634,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; cytoplasm; microtubule organizing center; nucleus,PF00271;PF00176;PF14773;,,,,,,,,,RAD26_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281] comp101623_c0_seq1,374,46.7914,1.07843908,6,36,,2.00E-13,P34147,Rho-related protein racA,Rho-related protein racA,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00651;PF00071;,,,,,,,,,RACA_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp101630_c0_seq1,347,44.6686,0.65728568,9,41,,7.00E-09,Q6DIR5,Testin,Testin,GO:0005938; GO:0005925; GO:0001755; GO:0042127; GO:0008270,cell cortex; focal adhesion; neural crest cell migration; regulation of cell proliferation; zinc ion binding,PF00412;PF06297;,1.00E-27,CHOYP_TES.1.1,,,,,,,TES_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),neural crest cell migration [GO:0001755]; regulation of cell proliferation [GO:0042127] comp101636_c0_seq1,256,62.8906,1.18983297,1,3,,6.00E-13,O34718,Major myo-inositol transporter IolT,Major myo-inositol transporter IolT,GO:0016021; GO:0005886; GO:0022891,integral to membrane; plasma membrane; substrate-specific transmembrane transporter activity,PF00083;,,,,,,,,,IOLT_BACSU,Bacillus subtilis (strain 168), comp101645_c0_seq1,325,49.8462,0.64752332,6,39,,1.00E-65,Q5RF84,Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2),Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2),GO:0005524; GO:0030433; GO:0070936; GO:0018279; GO:0004842,ATP binding; ER-associated protein catabolic process; protein K48-linked ubiquitination; protein N-linked glycosylation via asparagine; ubiquitin-protein ligase activity,PF00179;,2.00E-64,CHOYP_UB2G2.1.1,,,,,,,UB2G2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein K48-linked ubiquitination [GO:0070936]; protein N-linked glycosylation via asparagine [GO:0018279] comp101650_c1_seq2,235,30.2128,0.87571159,3,0,,,,,,,,,2.00E-11,CHOYP_contig_033669,,,,,,,,, comp101656_c1_seq1,498,45.1807,0.6319681,9,61,,7.00E-61,Q99P21,A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH),Adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH),GO:0051539; GO:0019104; GO:0006281; GO:0006284; GO:0046872; GO:0005739; GO:0005634,"4 iron, 4 sulfur cluster binding; DNA N-glycosylase activity; DNA repair; base-excision repair; metal ion binding; mitochondrion; nucleus",PF10576;PF00633;PF00730;PF14815;,3.00E-69,CHOYP_MUTYH.1.1,,,,,,,MUTYH_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; DNA repair [GO:0006281]; response to oxidative stress [GO:0006979] comp101661_c0_seq1,672,44.494,0.30187561,9,0,,1.00E-16,Q9Z1L4,Retinoschisin (X-linked juvenile retinoschisis protein homolog),Retinoschisin (X-linked juvenile retinoschisis protein homolog),GO:0016062; GO:0007155; GO:0005576; GO:0019897; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0005546; GO:0070273; GO:0010314; GO:0001786; GO:0010842,"adaptation of rhodopsin mediated signaling; cell adhesion; extracellular region; extrinsic to plasma membrane; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylserine binding; retina layer formation",PF00754;,,,,,,,,,XLRS1_MOUSE,Mus musculus (Mouse),adaptation of rhodopsin mediated signaling [GO:0016062]; cell adhesion [GO:0007155]; retina layer formation [GO:0010842] comp101661_c0_seq4,647,47.7589,0.43537519,19,19,,4.00E-27,P21956,Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47),Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47),GO:0001525; GO:0007155; GO:0009897; GO:0005615; GO:0019897; GO:0005178; GO:0006911; GO:0006910; GO:0008429; GO:0001786; GO:2000427; GO:0007338,"angiogenesis; cell adhesion; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; integrin binding; phagocytosis, engulfment; phagocytosis, recognition; phosphatidylethanolamine binding; phosphatidylserine binding; positive regulation of apoptotic cell clearance; single fertilization",PF00008;PF00754;,,,,,,,,,MFGM_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338]" comp101662_c0_seq1,308,45.1299,0.89603264,8,64,,1.00E-15,Q01177,"Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]","Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]",GO:0006915; GO:0007596; GO:0004175; GO:0022617; GO:0005615; GO:0031232; GO:0042730; GO:0043231; GO:0060716; GO:0071674; GO:0046716; GO:0045445; GO:0010812; GO:0051918; GO:0005886; GO:0051919; GO:0051603; GO:0004252; GO:0042246; GO:0048771; GO:0060707,apoptotic process; blood coagulation; endopeptidase activity; extracellular matrix disassembly; extracellular space; extrinsic to external side of plasma membrane; fibrinolysis; intracellular membrane-bounded organelle; labyrinthine layer blood vessel development; mononuclear cell migration; muscle cell cellular homeostasis; myoblast differentiation; negative regulation of cell-substrate adhesion; negative regulation of fibrinolysis; plasma membrane; positive regulation of fibrinolysis; proteolysis involved in cellular protein catabolic process; serine-type endopeptidase activity; tissue regeneration; tissue remodeling; trophoblast giant cell differentiation,PF00051;PF00024;PF00089;,,,,,,,,,PLMN_RAT,Rattus norvegicus (Rat),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trophoblast giant cell differentiation [GO:0060707] comp101676_c0_seq1,250,46,0.48208198,9,11,,2.00E-44,B4KNC5,F-box/SPRY domain-containing protein 1,F-box/SPRY domain-containing protein 1,GO:0030054; GO:0045886; GO:0007399; GO:0031594; GO:0007274; GO:0016567,cell junction; negative regulation of synaptic growth at neuromuscular junction; nervous system development; neuromuscular junction; neuromuscular synaptic transmission; protein ubiquitination,PF12937;PF00622;,1.00E-27,CHOYP_LOC662244.1.1,,,,,,,FBSP1_DROMO,Drosophila mojavensis (Fruit fly),negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; protein ubiquitination [GO:0016567] comp101676_c2_seq1,205,38.5366,0.96910908,1,0,,,,,,,,,3.00E-20,CHOYP_FBSP1.1.1,,,,,,,,, comp101681_c0_seq2,623,41.252,0.41645539,11,36,,2.00E-38,Q08D11,Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II),Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II),GO:0005789; GO:0016021; GO:0006659; GO:0016740,endoplasmic reticulum membrane; integral to membrane; phosphatidylserine biosynthetic process; transferase activity,PF03034;,1.00E-45,CHOYP_PTSS2.1.1,,,,,,,PTSS2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654] comp101721_c0_seq1,577,48.5269,0.35404118,17,26,,2.00E-06,Q08D51,Autophagy-related protein 2 homolog A,Autophagy-related protein 2 homolog A,GO:0006914,autophagy,PF13329;PF09333;PF12624;,,,,,,,,,ATG2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp101731_c1_seq1,369,57.9946,1.1650571,0,15,,9.00E-07,Q7N2E0,Transcriptional regulator LsrR,Transcriptional regulator LsrR,GO:0003677; GO:0030246; GO:0005737; GO:0006355; GO:0006351,"DNA binding; carbohydrate binding; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04198;,,,,,,,,,LSRR_PHOLL,Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp101762_c1_seq2,467,38.3298,0.58735209,4,4,,3.00E-10,P18106,Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer),Tyrosine-protein kinase Fer (EC 2.7.10.2),GO:0005524; GO:0051017; GO:0005912; GO:0007411; GO:0046664; GO:0007394; GO:0004715; GO:0005886; GO:0004713,"ATP binding; actin filament bundle assembly; adherens junction; axon guidance; dorsal closure, amnioserosa morphology change; dorsal closure, elongation of leading edge cells; non-membrane spanning protein tyrosine kinase activity; plasma membrane; protein tyrosine kinase activity",PF00611;PF07714;PF00017;,,,,,,,,,FPS_DROME,Drosophila melanogaster (Fruit fly),"actin filament bundle assembly [GO:0051017]; axon guidance [GO:0007411]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; photoreceptor cell morphogenesis [GO:0008594]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" comp101768_c0_seq1,301,65.7807,0.87356336,0,5,,4.00E-09,Q0S9A4,Ribose import ATP-binding protein RbsA (EC 3.6.3.17),Ribose import ATP-binding protein RbsA (EC 3.6.3.17),GO:0005524; GO:0006200; GO:0015407; GO:0005886,ATP binding; ATP catabolic process; monosaccharide-transporting ATPase activity; plasma membrane,PF00005;,,,,,,,,,RBSA_RHOSR,Rhodococcus jostii (strain RHA1), comp101771_c0_seq1,514,46.3035,1.02009441,3,85,,2.00E-14,Q8K385,Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),GO:0000293; GO:0016021; GO:0046872,ferric-chelate reductase activity; integral to membrane; metal ion binding,PF03351;PF02014;,,,,,,,,,FRRS1_MOUSE,Mus musculus (Mouse), comp101777_c0_seq2,808,40.4703,0.57785803,17,9,,5.00E-103,Q5RAS7,AMME syndrome candidate gene 1 protein homolog,AMME syndrome candidate gene 1 protein homolog,,,PF01871;,7.00E-87,CHOYP_PHUM_PHUM577920.1.1,,,,,,,AMMR1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp101799_c0_seq1,383,38.6423,0.43877656,15,28,,3.00E-23,Q2HJ46,E3 ubiquitin-protein ligase RNF8 (EC 6.3.2.-) (RING finger protein 8),E3 ubiquitin-protein ligase RNF8 (EC 6.3.2.-) (RING finger protein 8),GO:0051301; GO:0003682; GO:0000781; GO:0006303; GO:0070535; GO:0033523; GO:0042393; GO:0043486; GO:0045190; GO:0030496; GO:0007067; GO:0045900; GO:0005634; GO:0045739; GO:0070936; GO:0051865; GO:0042803; GO:0010212; GO:0035861; GO:0007286; GO:0000151; GO:0006511; GO:0004842; GO:0008270,"cell division; chromatin binding; chromosome, telomeric region; double-strand break repair via nonhomologous end joining; histone H2A K63-linked ubiquitination; histone H2B ubiquitination; histone binding; histone exchange; isotype switching; midbody; mitosis; negative regulation of translational elongation; nucleus; positive regulation of DNA repair; protein K48-linked ubiquitination; protein autoubiquitination; protein homodimerization activity; response to ionizing radiation; site of double-strand break; spermatid development; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding",PF00498;PF00097;,2.00E-19,CHOYP_LOC100372947.1.1,,,,,,,RNF8_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; isotype switching [GO:0045190]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511] comp101801_c0_seq2,837,38.9486,0.57325358,26,123,,5.00E-107,Q9JK24,Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR),Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR),GO:0001782; GO:0043029; GO:0032147; GO:0005509; GO:0005813; GO:0005737; GO:0005634; GO:0045579; GO:0002759; GO:0051900; GO:0048536,B cell homeostasis; T cell homeostasis; activation of protein kinase activity; calcium ion binding; centrosome; cytoplasm; nucleus; positive regulation of B cell differentiation; regulation of antimicrobial humoral response; regulation of mitochondrial depolarization; spleen development,,8.00E-118,CHOYP_P2R3C.1.1,,,,,,,P2R3C_MOUSE,Mus musculus (Mouse),activation of protein kinase activity [GO:0032147]; B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; regulation of antimicrobial humoral response [GO:0002759]; regulation of B cell activation [GO:0050864]; regulation of mitochondrial depolarization [GO:0051900]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029] comp101817_c0_seq1,571,44.8336,0.52419516,7,74,,2.00E-81,D3ZQG6,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,5.00E-68,CHOYP_BRAFLDRAFT_69647.1.5,,,,,,,TRIM2_RAT,Rattus norvegicus (Rat),regulation of neuron apoptotic process [GO:0043523] comp101822_c0_seq1,637,41.2873,0.96095707,27,36,,1.00E-22,Q5RA50,Protein FAM124A,Protein FAM124A,,,PF15067;,,,,,,,,,F124A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp101841_c0_seq1,1286,43.7792,0.9720052,93,54,,6.00E-118,Q9VX32,Rho GTPase-activating protein 190 (Rho GTPase-activating protein of 190 kDa),Rho GTPase-activating protein 190 (Rho GTPase-activating protein of 190 kDa),GO:0005525; GO:0005096; GO:0007415; GO:0005622; GO:0016319; GO:0045792; GO:0043547; GO:0050770; GO:0007264,GTP binding; GTPase activator activity; defasciculation of motor neuron axon; intracellular; mushroom body development; negative regulation of cell size; positive regulation of GTPase activity; regulation of axonogenesis; small GTPase mediated signal transduction,PF00071;PF00620;PF16512;,1.00E-80,CHOYP_LOC661306.1.3,,,,,,,RG190_DROME,Drosophila melanogaster (Fruit fly),defasciculation of motor neuron axon [GO:0007415]; mushroom body development [GO:0016319]; negative regulation of cell size [GO:0045792]; regulation of axonogenesis [GO:0050770]; Rho protein signal transduction [GO:0007266] comp101903_c0_seq1,784,40.4337,0.88039877,2,129,,3.00E-53,O42412,Type III iodothyronine deiodinase (EC 1.97.1.11) (5DIII) (DIOIII) (Type 3 DI) (Type-III 5'-deiodinase) (Fragment),Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) (Fragment),GO:0010008; GO:0042446; GO:0016021; GO:0005886; GO:0004800; GO:0033798,endosome membrane; hormone biosynthetic process; integral to membrane; plasma membrane; thyroxine 5'-deiodinase activity; thyroxine 5-deiodinase activity,PF00837;,,,,,,,,,IOD3_CHICK,Gallus gallus (Chicken),hormone biosynthetic process [GO:0042446] comp101909_c0_seq1,257,66.9261,1.06948446,0,2,,9.00E-53,Q6A7F4,Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),GO:0005524; GO:0002161; GO:0005737; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00133;,,,,,,,,,SYV_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),valyl-tRNA aminoacylation [GO:0006438] comp101923_c0_seq1,249,37.751,0.86936325,2,9,,6.00E-08,Q6PJG9,Leucine-rich repeat and fibronectin type-III domain-containing protein 4,Leucine-rich repeat and fibronectin type-III domain-containing protein 4,GO:0016021,integral to membrane,PF00041;PF07679;PF13855;,,,,,,,,,LRFN4_HUMAN,Homo sapiens (Human),axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268] comp101927_c2_seq1,523,46.8451,0.5312266,32,8,,6.00E-15,P42169,Putative casein kinase I C03C10.2 (EC 2.7.11.1),Putative casein kinase I C03C10.2 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,2.00E-65,CHOYP_LOC100908717.1.1,,,,,,,YKL2_CAEEL,Caenorhabditis elegans,peptidyl-serine phosphorylation [GO:0018105]; regulation of cell shape [GO:0008360] comp101935_c0_seq1,257,61.0895,1.42404753,3,16,,3.00E-06,D4GVF7,NADH-quinone oxidoreductase subunit C/D (EC 1.6.99.5) (NADH dehydrogenase I subunit C/D) (NDH-1 subunit C/D),NADH-quinone oxidoreductase subunit C/D (EC 1.6.5.11) (NADH dehydrogenase I subunit C/D) (NDH-1 subunit C/D),GO:0051287; GO:0008137; GO:0005886; GO:0048038; GO:0006810,NAD binding; NADH dehydrogenase (ubiquinone) activity; plasma membrane; quinone binding; transport,PF00329;PF00346;,,,,,,,,,NUOCD_HALVD,Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii),transport [GO:0006810] comp101937_c0_seq1,498,45.1807,0.67133857,7,43,,5.00E-13,Q63787,Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),GO:0016303; GO:0046935; GO:0005943; GO:0043125; GO:0007568; GO:0071398; GO:0006006; GO:0005158; GO:0008286; GO:0043560; GO:0005159; GO:0048009; GO:0045776; GO:0022408; GO:0010459; GO:0010656; GO:0045861; GO:0048662; GO:0043005; GO:0005634; GO:0005886; GO:0030335; GO:0010628; GO:0045663; GO:0001934; GO:0008022; GO:0043200; GO:0051591; GO:0071548; GO:0042493; GO:0032355; GO:0045471; GO:0009750; GO:0070848; GO:0010040; GO:0007584; GO:0032570; GO:0033574; GO:0001878,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-3-kinase regulator activity; 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ErbB-3 class receptor binding; aging; cellular response to fatty acid; glucose metabolic process; insulin receptor binding; insulin receptor signaling pathway; insulin receptor substrate binding; insulin-like growth factor receptor binding; insulin-like growth factor receptor signaling pathway; negative regulation of blood pressure; negative regulation of cell-cell adhesion; negative regulation of heart rate; negative regulation of muscle cell apoptotic process; negative regulation of proteolysis; negative regulation of smooth muscle cell proliferation; neuron projection; nucleus; plasma membrane; positive regulation of cell migration; positive regulation of gene expression; positive regulation of myoblast differentiation; positive regulation of protein phosphorylation; protein C-terminus binding; response to amino acid stimulus; response to cAMP; response to dexamethasone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to fructose stimulus; response to growth factor stimulus; response to iron(II) ion; response to nutrient; response to progesterone stimulus; response to testosterone stimulus; response to yeast",PF16454;PF00620;PF00017;,5.00E-35,CHOYP_LOC100372481.1.1,,,,,,,P85A_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular glucose homeostasis [GO:0001678]; cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of heart rate [GO:0010459]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of proteolysis [GO:0045861]; negative regulation of smooth muscle cell proliferation [GO:0048662]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to dexamethasone [GO:0071548]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848]; response to insulin [GO:0032868]; response to iron(II) ion [GO:0010040]; response to nutrient [GO:0007584]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to yeast [GO:0001878] comp101937_c1_seq1,263,42.2053,0.43651425,3,6,,9.00E-10,P11274,Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26),Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26),GO:0005524; GO:0005096; GO:0030675; GO:0005089; GO:0030036; GO:0007420; GO:0005829; GO:0042472; GO:0030336; GO:0050728; GO:0043314; GO:0050885; GO:0005543; GO:0005886; GO:0048008; GO:0050766; GO:0046777; GO:0004674; GO:0004713; GO:0051726; GO:0051056; GO:0032496; GO:0007264,ATP binding; GTPase activator activity; Rac GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; brain development; cytosol; inner ear morphogenesis; negative regulation of cell migration; negative regulation of inflammatory response; negative regulation of neutrophil degranulation; neuromuscular process controlling balance; phospholipid binding; plasma membrane; platelet-derived growth factor receptor signaling pathway; positive regulation of phagocytosis; protein autophosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of cell cycle; regulation of small GTPase mediated signal transduction; response to lipopolysaccharide; small GTPase mediated signal transduction,PF09036;PF00168;PF00620;PF00621;,,,,,,,,,BCR_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165] comp101943_c0_seq1,398,42.2111,0.56749043,2,19,,6.00E-17,P10280,Kunitz-type proteinase inhibitor 5 II (SA5 II),KappaPI-actitoxin-Avd3a (KappaPI-AITX-Avd3a) (Kunitz-type proteinase inhibitor 5 II) (SA5 II),GO:0005576; GO:0042151; GO:0004867,extracellular region; nematocyst; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,IP52_ANESU,Anemonia sulcata (Mediterranean snakelocks sea anemone), comp101943_c0_seq2,426,38.2629,0.5883376,3,16,,1.00E-13,P0C8W3,Protease inhibitor Hg1,Kunitz-type serine protease inhibitor Hg1 (Delta-KTx 1.1),GO:0044562; GO:0043655; GO:0004867,envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism; extracellular space of host; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,VPI1_HADGE,Hadrurus gertschi (Scorpion),envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism [GO:0044562] comp101949_c0_seq1,488,43.8525,1.02516154,0,10,,,,,,,,,,,5.00E-33,ruditapes_c9781,,,,,,, comp101952_c1_seq1,204,61.7647,1.13662005,0,12,,6.00E-06,Q8ZCA7,Copper-exporting P-type ATPase A (EC 3.6.3.54) (Cu(+)-exporting ATPase),Copper-exporting P-type ATPase A (EC 3.6.3.54) (Cu(+)-exporting ATPase),GO:0005524; GO:0019829; GO:0006825; GO:0016021; GO:0046872; GO:0005886,ATP binding; cation-transporting ATPase activity; copper ion transport; integral to membrane; metal ion binding; plasma membrane,PF00122;PF00403;,,,,,,,,,COPA_YERPE,Yersinia pestis, comp101953_c0_seq2,544,41.7279,0.55179314,1,0,,4.00E-08,Q9UKV5,E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78),E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78),GO:0030433; GO:0006928; GO:0030968; GO:0030176; GO:0051259; GO:0000209; GO:0004872; GO:0004842; GO:0008270,ER-associated protein catabolic process; cellular component movement; endoplasmic reticulum unfolded protein response; integral to endoplasmic reticulum membrane; protein oligomerization; protein polyubiquitination; receptor activity; ubiquitin-protein ligase activity; zinc ion binding,PF02845;PF13639;,,,,,,,,,AMFR_HUMAN,Homo sapiens (Human),aging [GO:0007568]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; learning or memory [GO:0007611]; movement of cell or subcellular component [GO:0006928]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein oligomerization [GO:0051259]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] comp101964_c0_seq1,955,38.3246,0.5440121,9,115,,2.00E-70,Q9HCU4,Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),GO:0004930; GO:0016055; GO:0005509; GO:0033326; GO:0042384; GO:0003341; GO:0005737; GO:0048813; GO:0007156; GO:0016021; GO:0021999; GO:0001764; GO:0007218; GO:0005886; GO:0022407; GO:0032880; GO:0006355; GO:0021591,"G-protein coupled receptor activity; Wnt receptor signaling pathway; calcium ion binding; cerebrospinal fluid secretion; cilium assembly; cilium movement; cytoplasm; dendrite morphogenesis; homophilic cell adhesion; integral to membrane; neural plate anterior/posterior regionalization; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of cell-cell adhesion; regulation of protein localization; regulation of transcription, DNA-dependent; ventricular system development",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR2_HUMAN,Homo sapiens (Human),"dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp101982_c0_seq1,400,43.75,0.92748879,3,45,,3.00E-15,P94494,Alanine racemase 2 (EC 5.1.1.1),Alanine racemase 2 (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR2_BACSU,Bacillus subtilis (strain 168),D-alanine biosynthetic process [GO:0030632] comp101983_c0_seq2,352,47.7273,0.25142653,0,0,,5.00E-27,Q86X10,Ral GTPase-activating protein subunit beta (p170),Ral GTPase-activating protein subunit beta (p170),GO:0017123; GO:0032484; GO:0032859; GO:0046982; GO:0060178,Ral GTPase activator activity; Ral protein signal transduction; activation of Ral GTPase activity; protein heterodimerization activity; regulation of exocyst localization,,8.00E-25,CHOYP_BRAFLDRAFT_116449.1.1,,,,,,,RLGPB_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] comp101984_c0_seq1,628,45.2229,0.9048138,33,20,,1.00E-16,O15085,Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF),Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF),GO:0001664; GO:0007186; GO:0005096; GO:0005089; GO:0007266; GO:0030036; GO:0097190; GO:0007411; GO:0000910; GO:0005829; GO:0030010; GO:0016020; GO:0048011; GO:0005543; GO:0043547; GO:0043065; GO:0045893; GO:0035023; GO:0001558; GO:0051056; GO:0006941; GO:0038032,"G-protein coupled receptor binding; G-protein coupled receptor signaling pathway; GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; Rho protein signal transduction; actin cytoskeleton organization; apoptotic signaling pathway; axon guidance; cytokinesis; cytosol; establishment of cell polarity; membrane; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of GTPase activity; positive regulation of apoptotic process; positive regulation of transcription, DNA-dependent; regulation of Rho protein signal transduction; regulation of cell growth; regulation of small GTPase mediated signal transduction; striated muscle contraction; termination of G-protein coupled receptor signaling pathway",PF00595;PF09128;PF00621;,,,,,,,,,ARHGB_HUMAN,Homo sapiens (Human),"actin cytoskeleton organization [GO:0030036]; cytokinesis [GO:0000910]; establishment of cell polarity [GO:0030010]; G-protein coupled receptor signaling pathway [GO:0007186]; movement of cell or subcellular component [GO:0006928]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell growth [GO:0001558]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; striated muscle contraction [GO:0006941]" comp101984_c1_seq1,882,43.9909,0.54484309,27,60,,7.00E-09,Q61210,Rho guanine nucleotide exchange factor 1 (Lbc's second cousin) (Lymphoid blast crisis-like 2),Rho guanine nucleotide exchange factor 1 (Lbc's second cousin) (Lymphoid blast crisis-like 2),GO:0005096; GO:0005089; GO:0005737; GO:0016020; GO:0005543; GO:0043547; GO:0035023; GO:0038032,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; cytoplasm; membrane; phospholipid binding; positive regulation of GTPase activity; regulation of Rho protein signal transduction; termination of G-protein coupled receptor signaling pathway,PF09128;PF00621;,,,,,,,,,ARHG1_MOUSE,Mus musculus (Mouse),regulation of Rho protein signal transduction [GO:0035023] comp101984_c1_seq2,352,40.9091,0.50844032,0,6,,1.00E-10,P34885,Protein kinase C-like 1B (PKC1B) (EC 2.7.11.13),Protein kinase C-like 1B (PKC1B) (EC 2.7.11.13),GO:0005524; GO:0000165; GO:0005623; GO:0006935; GO:0005737; GO:0005856; GO:0040024; GO:0048009; GO:0016020; GO:0046872; GO:2001024; GO:0007218; GO:0004697; GO:0040012; GO:0050975; GO:0016079,ATP binding; MAPK cascade; cell; chemotaxis; cytoplasm; cytoskeleton; dauer larval development; insulin-like growth factor receptor signaling pathway; membrane; metal ion binding; negative regulation of response to drug; neuropeptide signaling pathway; protein kinase C activity; regulation of locomotion; sensory perception of touch; synaptic vesicle exocytosis,PF00130;PF00168;PF00069;PF00433;,,,,,,,,,KPC1B_CAEEL,Caenorhabditis elegans,associative learning [GO:0008306]; chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; dauer larval development [GO:0040024]; dense core granule exocytosis [GO:1990504]; insulin-like growth factor receptor signaling pathway [GO:0048009]; MAPK cascade [GO:0000165]; negative regulation of response to drug [GO:2001024]; neuropeptide signaling pathway [GO:0007218]; neurotransmitter secretion [GO:0007269]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of positive chemotaxis [GO:0050927]; protein phosphorylation [GO:0006468]; regulation of chemotaxis [GO:0050920]; regulation of locomotion [GO:0040012]; response to salt [GO:1902074]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of touch [GO:0050975]; sensory processing [GO:0050893]; synaptic vesicle exocytosis [GO:0016079] comp101998_c0_seq1,430,43.2558,0.35142881,13,45,,1.00E-34,Q7M456,Ribonuclease Oy (RNase Oy) (EC 3.1.27.-),Ribonuclease Oy (RNase Oy) (EC 3.1.27.-),GO:0003723; GO:0005576; GO:0090305; GO:0033897,RNA binding; extracellular region; nucleic acid phosphodiester bond hydrolysis; ribonuclease T2 activity,PF00445;,,,,,,,,,RNOY_CRAGI,Crassostrea gigas (Pacific oyster) (Crassostrea angulata), comp102027_c0_seq1,365,40.8219,0.52757153,19,15,,2.00E-11,Q8I7P9,Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305; GO:0005634; GO:0008233; GO:0006508; GO:0006313,"DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; peptidase activity; proteolysis; transposition, DNA-mediated",PF00665;PF00078;,,,,,,,,,POL5_DROME,Drosophila melanogaster (Fruit fly),"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp102034_c0_seq1,565,54.8673,0.73059856,12,55,,2.00E-11,P16537,Protein SPEC3,Protein SPEC3,GO:0000139; GO:0005929; GO:0016021,Golgi membrane; cilium; integral to membrane,PF15795;,,,,,,,,,SPC3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp102043_c0_seq1,425,40,0.6543815,7,37,,5.00E-52,Q8CCB4,Vacuolar protein sorting-associated protein 53 homolog,Vacuolar protein sorting-associated protein 53 homolog,GO:0005794; GO:0010008; GO:0015031,Golgi apparatus; endosome membrane; protein transport,PF04100;,2.00E-59,CHOYP_VPS53.1.1,,,,,,,VPS53_MOUSE,Mus musculus (Mouse),"endocytic recycling [GO:0032456]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp102058_c0_seq1,537,44.6927,0.33739926,3,0,,1.00E-09,Q8BX70,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp102058_c0_seq2,640,45.625,0.33431403,6,0,,5.00E-55,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,5.00E-24,CHOYP_VP13D.1.3,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp102060_c0_seq1,293,40.273,0.69566028,2,38,,1.00E-13,Q9HCU4,Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),GO:0004930; GO:0016055; GO:0005509; GO:0033326; GO:0042384; GO:0003341; GO:0005737; GO:0048813; GO:0007156; GO:0016021; GO:0021999; GO:0001764; GO:0007218; GO:0005886; GO:0022407; GO:0032880; GO:0006355; GO:0021591,"G-protein coupled receptor activity; Wnt receptor signaling pathway; calcium ion binding; cerebrospinal fluid secretion; cilium assembly; cilium movement; cytoplasm; dendrite morphogenesis; homophilic cell adhesion; integral to membrane; neural plate anterior/posterior regionalization; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of cell-cell adhesion; regulation of protein localization; regulation of transcription, DNA-dependent; ventricular system development",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR2_HUMAN,Homo sapiens (Human),"dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp102069_c1_seq1,223,51.1211,0.42198651,6,2,,6.00E-06,A0JNA8,PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),GO:0006310; GO:0006281; GO:0016363; GO:0006355; GO:0006351,"DNA recombination; DNA repair; nuclear matrix; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00533;PF12738;PF16770;,,,,,,,,,PAXI1_BOVIN,Bos taurus (Bovine),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp102072_c0_seq1,235,46.8085,0.85819736,12,0,,,,,,,,,6.00E-11,CHOYP_MAST4.1.1,,,,,,,,, comp102081_c1_seq1,334,50.5988,0.52418678,15,0,,1.00E-36,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,3.00E-36,CHOYP_BRAFLDRAFT_98113.1.1,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp102098_c0_seq1,203,33.4975,0.35417526,2,4,,,,,,,,,,,3.00E-12,ruditapes2_c2444,,,,,,, comp102103_c0_seq1,715,40.6993,0.78464038,2,76,,2.00E-10,Q51330,Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein),Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein),GO:0015297; GO:0016021; GO:0006811; GO:0005886,antiporter activity; integral to membrane; ion transport; plasma membrane,PF07690;,,,,,,,,,OXLT_OXAFO,Oxalobacter formigenes,ion transport [GO:0006811] comp102107_c1_seq1,270,42.2222,0.17108821,6,0,,4.00E-09,Q9VR91,Probable E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),Probable E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0005814; GO:0005737; GO:0020037; GO:0046872; GO:0005634; GO:0042787; GO:0004842,centriole; cytoplasm; heme binding; metal ion binding; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF11515;PF00173;PF00632;PF06701;PF00415;,,,,,,,,,HERC2_DROME,Drosophila melanogaster (Fruit fly),protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp102140_c0_seq1,477,45.4927,0.37035287,40,12,,1.00E-09,Q9X0Y1,Phosphorylated carbohydrates phosphatase TM_1254 (EC 3.1.3.-),Phosphorylated carbohydrates phosphatase TM_1254 (EC 3.1.3.-),GO:0005975; GO:0016787; GO:0046872,carbohydrate metabolic process; hydrolase activity; metal ion binding,PF13419;,,,,,,,,,P1254_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),carbohydrate metabolic process [GO:0005975] comp10215_c0_seq1,317,43.8486,0.39667754,0,5,,7.00E-20,Q9Z1T6,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235),GO:0000285; GO:0016308; GO:0052810; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0030659; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0032288; GO:0048471; GO:0012506; GO:0008270,1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; myelin assembly; perinuclear region of cytoplasm; vesicle membrane; zinc ion binding,PF00118;PF00610;PF01363;PF01504;,2.00E-43,CHOYP_FYV1.1.1,,,,,,,FYV1_MOUSE,Mus musculus (Mouse),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp102175_c0_seq1,603,44.4444,0.81019673,16,70,,1.00E-17,Q8VCM5,Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 6.3.2.-) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase),Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 6.3.2.-) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase),GO:0019789; GO:0007257; GO:0006919; GO:0042802; GO:0031307; GO:0000266; GO:0051646; GO:0030308; GO:0010637; GO:0005634; GO:0005777; GO:0043123; GO:0090141; GO:0033235; GO:0050821; GO:0016925; GO:1901028; GO:0004871; GO:0004842; GO:0008270,SUMO ligase activity; activation of JUN kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; identical protein binding; integral to mitochondrial outer membrane; mitochondrial fission; mitochondrion localization; negative regulation of cell growth; negative regulation of mitochondrial fusion; nucleus; peroxisome; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of mitochondrial fission; positive regulation of protein sumoylation; protein stabilization; protein sumoylation; regulation of mitochondrial outer membrane permeabilization; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF12483;,,,,,,,,,MUL1_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; negative regulation of cell growth [GO:0030308]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of innate immune response [GO:0045824]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of dendrite extension [GO:1903861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein sumoylation [GO:0033235]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901028]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647] comp102198_c0_seq1,222,50,1.05904456,0,5,,1.00E-06,Q5XGM3,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,6.00E-30,CHOYP_LOC100371248.2.2,,,,,,,BHMT1_XENLA,Xenopus laevis (African clawed frog),amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086] comp102198_c1_seq1,275,42.9091,0.99252137,4,44,,1.00E-07,Q5RFG2,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,,,,,,,,,BHMT1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086] comp102199_c0_seq1,319,61.442,1.15316449,2,8,,1.00E-66,Q6A763,DNA polymerase IV (Pol IV) (EC 2.7.7.7),DNA polymerase IV (Pol IV) (EC 2.7.7.7),GO:0006281; GO:0006261; GO:0003887; GO:0005737; GO:0003684; GO:0000287,DNA repair; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; cytoplasm; damaged DNA binding; magnesium ion binding,PF00817;PF11799;,,,,,,,,,DPO4_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281] comp102211_c0_seq1,224,41.9643,0.10260122,0,9,,3.00E-26,A2VD33,Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase),Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase),GO:0006777; GO:0008265; GO:0030151; GO:0043545; GO:0030170; GO:0016740,Mo-molybdopterin cofactor biosynthetic process; Mo-molybdopterin cofactor sulfurase activity; molybdenum ion binding; molybdopterin cofactor metabolic process; pyridoxal phosphate binding; transferase activity,PF00266;PF03473;PF03476;,1.00E-13,CHOYP_LOC583644.1.1,,,,,,,MOCOS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),molybdopterin cofactor metabolic process [GO:0043545]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp102213_c2_seq1,937,40.8751,0.35815237,26,87,,3.00E-09,Q99LC9,Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1),Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1),GO:0005524; GO:0042623; GO:0005829; GO:0005778; GO:0016561; GO:0050821,"ATP binding; ATPase activity, coupled; cytosol; peroxisomal membrane; protein import into peroxisome matrix, translocation; protein stabilization",PF00004;,,,,,,,,,PEX6_MOUSE,Mus musculus (Mouse),"peroxisome organization [GO:0007031]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]" comp102219_c1_seq1,314,50.9554,0.59146273,8,0,,4.00E-27,Q8BQZ4,Ral GTPase-activating protein subunit beta (p170),Ral GTPase-activating protein subunit beta (p170),GO:0017123; GO:0032484; GO:0032859; GO:0005829; GO:0046982; GO:0060178,Ral GTPase activator activity; Ral protein signal transduction; activation of Ral GTPase activity; cytosol; protein heterodimerization activity; regulation of exocyst localization,,4.00E-41,CHOYP_BRAFLDRAFT_116449.1.1,,,,,,,RLGPB_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; membrane organization [GO:0061024]; Ral protein signal transduction [GO:0032484]; regulation of exocyst localization [GO:0060178]; regulation of protein localization [GO:0032880]; regulation of small GTPase mediated signal transduction [GO:0051056] comp102229_c0_seq1,237,43.8819,0.36857025,8,0,,6.00E-18,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,2.00E-23,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp10223_c0_seq1,216,40.2778,1.3001368,0,5,,3.00E-13,P49003,Bone morphogenetic protein 5 (BMP-5),Bone morphogenetic protein 5 (BMP-5),GO:0070700; GO:0051216; GO:0005615; GO:0040007; GO:0030539; GO:0032348; GO:0008285; GO:2000065; GO:0043569; GO:0001503; GO:0007389; GO:2000105; GO:1900006; GO:0050679; GO:0010862; GO:0045944; GO:0001501; GO:0003323,BMP receptor binding; cartilage development; extracellular space; growth; male genitalia development; negative regulation of aldosterone biosynthetic process; negative regulation of cell proliferation; negative regulation of cortisol biosynthetic process; negative regulation of insulin-like growth factor receptor signaling pathway; ossification; pattern specification process; positive regulation of DNA-dependent DNA replication; positive regulation of dendrite development; positive regulation of epithelial cell proliferation; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; skeletal system development; type B pancreatic cell development,PF00019;PF00688;,2.00E-22,CHOYP_BRAFLDRAFT_80287.1.1,7.00E-33,ruditapes_c20414,,,,,BMP5_MOUSE,Mus musculus (Mouse),BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell development [GO:0048468]; growth [GO:0040007]; male genitalia development [GO:0030539]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of steroid biosynthetic process [GO:0010894]; ossification [GO:0001503]; pattern specification process [GO:0007389]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-dependent DNA replication [GO:2000105]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; type B pancreatic cell development [GO:0003323] comp102245_c0_seq1,535,44.1121,0.45483458,11,57,,4.00E-36,Q9NVH0,Exonuclease 3'-5' domain-containing protein 2 (Exonuclease 3'-5' domain-like-containing protein 2),Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;,,,,,,,,,EXD2_HUMAN,Homo sapiens (Human),DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305] comp102252_c0_seq1,202,45.0495,0.29506537,5,2,,2.00E-15,P50416,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0006853; GO:0042755; GO:0006635; GO:0006006; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; carnitine shuttle; eating behavior; fatty acid beta-oxidation; glucose metabolic process; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; triglyceride metabolic process,PF00755;PF16484;,,,,,,,,,CPT1A_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641] comp102255_c0_seq1,742,40.8356,0.52667117,20,76,,1.00E-42,P42680,Tyrosine-protein kinase Tec (EC 2.7.10.2),Tyrosine-protein kinase Tec (EC 2.7.10.2),GO:0005524; GO:0050853; GO:0038095; GO:0005856; GO:0005829; GO:0045087; GO:0007229; GO:0007243; GO:0046872; GO:0004715; GO:0005543; GO:0005886; GO:0010543,ATP binding; B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; cytoskeleton; cytosol; innate immune response; integrin-mediated signaling pathway; intracellular protein kinase cascade; metal ion binding; non-membrane spanning protein tyrosine kinase activity; phospholipid binding; plasma membrane; regulation of platelet activation,PF00779;PF00169;PF07714;PF00017;PF00018;,1.00E-58,CHOYP_BTKL.1.1,,,,,,,TEC_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; regulation of platelet activation [GO:0010543]; tissue regeneration [GO:0042246]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp102256_c1_seq1,339,42.1829,0.34680024,7,0,,4.00E-32,Q8TDB6,E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),GO:0005737; GO:0006302; GO:0042393; GO:0010390; GO:0005634; GO:0004842; GO:0008270,cytoplasm; double-strand break repair; histone binding; histone monoubiquitination; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,DTX3L_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209] comp102274_c0_seq1,441,58.2766,0.99115661,0,15,,3.00E-47,A5U8S4,Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS),Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS),GO:0005524; GO:0005737; GO:0004824; GO:0006430; GO:0000287; GO:0003676,ATP binding; cytoplasm; lysine-tRNA ligase activity; lysyl-tRNA aminoacylation; magnesium ion binding; nucleic acid binding,PF00152;PF01336;,,,,,,,,,SYK_MYCTA,Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra),lysyl-tRNA aminoacylation [GO:0006430] comp102288_c0_seq1,367,42.2343,1.11995103,14,54,,6.00E-72,P02556,Tubulin beta chain (Beta-tubulin) (Fragment),Tubulin beta chain (Beta-tubulin) (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF03953;,2.00E-70,CHOYP_LOC100533349.1.5,3.00E-78,ruditapes2_lrc3505,,,,,TBB_LYTPI,Lytechinus pictus (Painted sea urchin),microtubule-based process [GO:0007017] comp102288_c1_seq1,437,44.8513,1.00501152,8,38,,3.00E-23,A0AAL4,Tubulin alpha chain (Alpha-tubulin) (Fragment),Tubulin alpha chain (Alpha-tubulin) (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,1.00E-98,CHOYP_contig_015657,3.00E-104,ruditapes_c6496,,,,,TBA_DICPU,Dictyostelium purpureum (Slime mold),microtubule-based process [GO:0007017] comp102288_c2_seq1,517,45.2611,0.85504522,3,6,,6.00E-95,O44388,Tubulin beta chain (Beta-tubulin),Tubulin beta chain (Beta-tubulin),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,1.00E-87,CHOYP_LOC373275.2.7,2.00E-96,ruditapes2_c4168,,,,,TBB_TRITR,Trichuris trichiura (Whipworm) (Trichocephalus trichiurus),microtubule-based process [GO:0007017] comp102288_c2_seq2,462,43.29,0.90281622,4,0,,2.00E-17,P40633,Tubulin gamma chain (Gamma-tubulin),Tubulin gamma chain (Gamma-tubulin),GO:0005525; GO:0003924; GO:0031122; GO:0000930; GO:0005874; GO:0007020; GO:0051258; GO:0005816,GTP binding; GTPase activity; cytoplasmic microtubule organization; gamma-tubulin complex; microtubule; microtubule nucleation; protein polymerization; spindle pole body,PF00091;PF03953;,,,,,,,,,TBG_COCHE,Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern corn leaf blight fungus) (Bipolaris maydis),"cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]; mitotic cytokinesis, site selection [GO:1902408]; mitotic spindle midzone assembly [GO:0051256]" comp102298_c1_seq1,323,38.3901,0.42320155,7,0,,6.00E-10,Q9NXL6,SID1 transmembrane family member 1,SID1 transmembrane family member 1,GO:0051033; GO:0033227; GO:0016021,RNA transmembrane transporter activity; dsRNA transport; integral to membrane,PF13965;,,,,,,,,,SIDT1_HUMAN,Homo sapiens (Human),dsRNA transport [GO:0033227] comp102311_c0_seq1,367,42.5068,0.66579442,4,37,,2.00E-06,Q8IUL8,Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2],Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2],GO:0005578,proteinaceous extracellular matrix,PF13330;PF00090;,,,,,,,,,CILP2_HUMAN,Homo sapiens (Human), comp102311_c1_seq1,913,48.0832,0.96862389,6,84,,2.00E-30,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp102313_c0_seq1,802,42.1446,0.22542759,23,116,,9.00E-66,Q2KHS5,2-acylglycerol O-acyltransferase 2-A (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2-A) (MGAT2-A) (Monoacylglycerol O-acyltransferase 2-A),2-acylglycerol O-acyltransferase 2-A (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2-A) (MGAT2-A) (Monoacylglycerol O-acyltransferase 2-A),GO:0003846; GO:0005789; GO:0006071; GO:0016021; GO:0019432,2-acylglycerol O-acyltransferase activity; endoplasmic reticulum membrane; glycerol metabolic process; integral to membrane; triglyceride biosynthetic process,PF03982;,,,,,,,,,MOG2A_XENLA,Xenopus laevis (African clawed frog),glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] comp102314_c0_seq1,385,41.8182,0.96955128,1,63,,1.00E-21,A1DZY4,Ras-like protein family member 11A-like,Ras-like protein family member 11A-like,GO:0005525; GO:0003924; GO:0016020; GO:0005730; GO:0045943; GO:0007264; GO:0006351,"GTP binding; GTPase activity; membrane; nucleolus; positive regulation of transcription from RNA polymerase I promoter; small GTPase mediated signal transduction; transcription, DNA-dependent",PF00071;,,,,,,,,,RSLBL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; small GTPase mediated signal transduction [GO:0007264]; transcription, DNA-templated [GO:0006351]" comp102316_c0_seq1,204,48.5294,0.25540481,1,4,,1.00E-07,Q9NQG7,Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog),Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog),GO:0007596; GO:0007599; GO:0005764; GO:0007040; GO:0030318; GO:0042470; GO:0016020; GO:0042827; GO:0048075; GO:0050821; GO:0006605,blood coagulation; hemostasis; lysosome; lysosome organization; melanocyte differentiation; melanosome; membrane; platelet dense granule; positive regulation of eye pigmentation; protein stabilization; protein targeting,,,,,,,,,,HPS4_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; hemostasis [GO:0007599]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605] comp102322_c0_seq2,680,43.3824,0.34450958,11,0,,2.00E-17,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp102323_c2_seq1,769,42.9129,0.26265963,0,15,,2.00E-86,Q0II59,Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase),Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase),GO:0005524; GO:0008283; GO:0005829; GO:0031403; GO:0000287; GO:0005634; GO:0030955; GO:0009443; GO:0008478; GO:0030170; GO:0031402; GO:0008270,ATP binding; cell proliferation; cytosol; lithium ion binding; magnesium ion binding; nucleus; potassium ion binding; pyridoxal 5'-phosphate salvage; pyridoxal kinase activity; pyridoxal phosphate binding; sodium ion binding; zinc ion binding,PF08543;,7.00E-55,CHOYP_PDXK.1.1,,,,,,,PDXK_BOVIN,Bos taurus (Bovine),cell proliferation [GO:0008283]; pyridoxal 5'-phosphate salvage [GO:0009443]; vitamin B6 metabolic process [GO:0042816] comp102323_c2_seq2,780,41.9231,0.27242119,0,9,,1.00E-70,Q8W1X2,Pyridoxal kinase (EC 2.7.1.35) (Protein SALT OVERLY SENSITIVE 4) (Pyridoxal kinase-like protein SOS4) (Pyridoxine kinase),"Pyridoxal kinase (EC 2.7.1.35) (Protein SALT OVERLY SENSITIVE 4) (Pyridoxal kinase-like protein SOS4) (Pyridoxine kinase) [Cleaved into: Pyridoxal kinase, N-terminally processed]",GO:0005524; GO:0005829; GO:0042538; GO:0046872; GO:0009443; GO:0008478; GO:0008615; GO:0010054,ATP binding; cytosol; hyperosmotic salinity response; metal ion binding; pyridoxal 5'-phosphate salvage; pyridoxal kinase activity; pyridoxine biosynthetic process; trichoblast differentiation,PF08543;,,,,,,,,,PDXK_ARATH,Arabidopsis thaliana (Mouse-ear cress),hyperosmotic salinity response [GO:0042538]; pyridoxal 5'-phosphate salvage [GO:0009443]; pyridoxine biosynthetic process [GO:0008615]; trichoblast differentiation [GO:0010054] comp102327_c0_seq1,908,37.2247,0.70264658,60,67,,1.00E-22,P47787,Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1),Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1),GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705; GO:0001516; GO:0004796,"endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; prostaglandin biosynthetic process; thromboxane-A synthase activity",PF00067;,,,,,,,,,THAS_PIG,Sus scrofa (Pig),prostaglandin biosynthetic process [GO:0001516] comp102328_c0_seq1,768,44.9219,0.49102785,32,48,,3.00E-64,Q5CZL1,Ganglioside-induced differentiation-associated protein 2,Ganglioside-induced differentiation-associated protein 2,,,PF13716;PF01661;,5.00E-31,CHOYP_GDAP2.1.1,,,,,,,GDAP2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp102349_c0_seq1,314,44.9045,0.5070474,10,10,,7.00E-14,Q02563,Synaptic vesicle glycoprotein 2A (Synaptic vesicle protein 2) (Synaptic vesicle protein 2A),Synaptic vesicle glycoprotein 2A (Synaptic vesicle protein 2) (Synaptic vesicle protein 2A),GO:0005911; GO:0006874; GO:0005783; GO:0016021; GO:0031594; GO:0043005; GO:0006836; GO:0048786; GO:0004872; GO:0030672; GO:0022857; GO:0005215,cell-cell junction; cellular calcium ion homeostasis; endoplasmic reticulum; integral to membrane; neuromuscular junction; neuron projection; neurotransmitter transport; presynaptic active zone; receptor activity; synaptic vesicle membrane; transmembrane transporter activity; transporter activity,PF07690;PF13599;PF00083;,,,,,,,,,SV2A_RAT,Rattus norvegicus (Rat),cellular calcium ion homeostasis [GO:0006874]; neurotransmitter transport [GO:0006836] comp102356_c0_seq1,276,50,0.35513287,11,6,,2.00E-17,Q8WXD9,Caskin-1 (CASK-interacting protein 1),Caskin-1 (CASK-interacting protein 1),GO:0005737; GO:0007165,cytoplasm; signal transduction,PF12796;PF16632;PF00536;PF07653;,4.00E-21,CHOYP_CSKI2.1.1,,,,,,,CSKI1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp102365_c0_seq1,207,58.4541,1.13850495,3,0,,3.00E-40,Q6A976,Endoribonuclease YbeY (EC 3.1.-.-),Endoribonuclease YbeY (EC 3.1.-.-),GO:0005737; GO:0004521; GO:0004222; GO:0090305; GO:0006364; GO:0008270,cytoplasm; endoribonuclease activity; metalloendopeptidase activity; nucleic acid phosphodiester bond hydrolysis; rRNA processing; zinc ion binding,PF02130;,,,,,,,,,RRMF_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),rRNA processing [GO:0006364] comp102372_c0_seq1,404,40.5941,1.2091431,4,81,,2.00E-23,Q9R0W9,Neuronal acetylcholine receptor subunit alpha-6,Neuronal acetylcholine receptor subunit alpha-6,GO:0004889; GO:0005892; GO:0030054; GO:0051899; GO:0045211; GO:0014059,acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; cell junction; membrane depolarization; postsynaptic membrane; regulation of dopamine secretion,PF02931;PF02932;,,,,,,,,,ACHA6_MOUSE,Mus musculus (Mouse),"membrane depolarization [GO:0051899]; neuromuscular synaptic transmission [GO:0007274]; regulation of dopamine secretion [GO:0014059]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" comp102385_c0_seq1,220,43.6364,1.16933633,2,33,,,,,,,,,5.00E-12,CHOYP_LOC100373752.3.4,,,,,,,,, comp102391_c0_seq1,258,40.3101,0.67675522,3,7,,3.00E-27,Q69ZN6,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0046835; GO:0030154; GO:0016021; GO:0005634; GO:0009306,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; carbohydrate phosphorylation; cell differentiation; integral to membrane; nucleus; protein secretion,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,1.00E-13,CHOYP_GNPTA.2.3,,,,,,,GNPTA_MOUSE,Mus musculus (Mouse),carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; protein secretion [GO:0009306]; secretion of lysosomal enzymes [GO:0033299] comp102414_c0_seq1,517,40.8124,0.42936245,15,30,,2.00E-70,Q7ZW86,Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8),Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8),GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,2.00E-59,CHOYP_LOC100701406.1.1,5.00E-14,ruditapes_c1358,,,,,CWC27_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein folding [GO:0006457] comp102417_c0_seq1,863,42.9896,0.5134612,26,31,,5.00E-64,Q8N357,Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog),Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog),GO:0005794; GO:0016021; GO:0005765; GO:0005739; GO:1901029; GO:0005634; GO:0008284; GO:0006810,Golgi apparatus; integral to membrane; lysosomal membrane; mitochondrion; negative regulation of mitochondrial outer membrane permeabilization; nucleus; positive regulation of cell proliferation; transport,PF06027;,2.00E-44,CHOYP_S35F6.1.1,,,,,,,CB018_HUMAN,Homo sapiens (Human),negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; positive regulation of cell proliferation [GO:0008284] comp102426_c0_seq1,295,43.0508,0.66170656,7,25,,1.00E-24,Q5XHB2,Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48),Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48),GO:0005737; GO:0005634; GO:0035335; GO:0046330; GO:0004725; GO:0008138; GO:0042127; GO:0007179,cytoplasm; nucleus; peptidyl-tyrosine dephosphorylation; positive regulation of JNK cascade; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of cell proliferation; transforming growth factor beta receptor signaling pathway,PF00782;,,,,,,,,,DUS22_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),positive regulation of JNK cascade [GO:0046330]; regulation of cell proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp102443_c0_seq1,837,45.6392,0.57402257,29,40,,6.00E-94,Q5R5F8,Pantothenate kinase 4 (EC 2.7.1.33) (Pantothenic acid kinase 4),Pantothenate kinase 4 (EC 2.7.1.33) (Pantothenic acid kinase 4),GO:0005524; GO:0015937; GO:0005737; GO:0004594,ATP binding; coenzyme A biosynthetic process; cytoplasm; pantothenate kinase activity,PF01937;PF03630;,5.00E-38,CHOYP_BRAFLDRAFT_72760.1.1,,,,,,,PANK4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),coenzyme A biosynthetic process [GO:0015937] comp102449_c0_seq1,865,42.1965,0.54902863,50,37,,5.00E-09,Q5SXM2,snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit),snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit),GO:0003677; GO:0003682; GO:0005654; GO:0003700; GO:0042795; GO:0042796; GO:0019185,DNA binding; chromatin binding; nucleoplasm; sequence-specific DNA binding transcription factor activity; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter; snRNA-activating protein complex,PF00249;,,,,,,,,,SNPC4_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; snRNA transcription [GO:0009301]; snRNA transcription from RNA polymerase III promoter [GO:0042796]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366] comp102461_c0_seq1,258,44.5736,0.6632622,2,4,,4.00E-33,Q12965,Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E),Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E),GO:0005524; GO:0042623; GO:0051015; GO:0030048; GO:0005912; GO:0005516; GO:0005911; GO:0030136; GO:0005737; GO:0006897; GO:0032836; GO:0003094; GO:0072015; GO:0001701; GO:0000146; GO:0016459; GO:0035091; GO:0048008; GO:0035166; GO:0001570,"ATP binding; ATPase activity, coupled; actin filament binding; actin filament-based movement; adherens junction; calmodulin binding; cell-cell junction; clathrin-coated vesicle; cytoplasm; endocytosis; glomerular basement membrane development; glomerular filtration; glomerular visceral epithelial cell development; in utero embryonic development; microfilament motor activity; myosin complex; phosphatidylinositol binding; platelet-derived growth factor receptor signaling pathway; post-embryonic hemopoiesis; vasculogenesis",PF00063;PF06017;PF00018;,3.00E-29,CHOYP_MYO1E.1.1,,,,,,,MYO1E_HUMAN,Homo sapiens (Human),actin filament-based movement [GO:0030048]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015]; in utero embryonic development [GO:0001701]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570] comp102468_c0_seq1,269,49.0706,0.43882659,2,9,,3.00E-24,O75716,Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK),Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK),GO:0005524; GO:0005798; GO:0001077; GO:0071560; GO:0016020; GO:0004715; GO:0048471; GO:0046777; GO:0004674,ATP binding; Golgi-associated vesicle; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to transforming growth factor beta stimulus; membrane; non-membrane spanning protein tyrosine kinase activity; perinuclear region of cytoplasm; protein autophosphorylation; protein serine/threonine kinase activity,PF00069;,1.00E-21,CHOYP_DCTN2.1.1,,,,,,,STK16_HUMAN,Homo sapiens (Human),cellular response to transforming growth factor beta stimulus [GO:0071560]; protein autophosphorylation [GO:0046777] comp102491_c0_seq1,370,47.2973,0.58150895,9,25,,2.00E-55,Q9Y217,Myotubularin-related protein 6 (EC 3.1.3.-),Myotubularin-related protein 6 (EC 3.1.3.-),GO:0015269; GO:0005829; GO:0005635; GO:0006661; GO:0004722; GO:0004725; GO:0044281,calcium-activated potassium channel activity; cytosol; nuclear envelope; phosphatidylinositol biosynthetic process; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; small molecule metabolic process,PF06602;,3.00E-50,CHOYP_ISCW_ISCW018501.2.2,,,,,,,MTMR6_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470] comp102500_c0_seq1,1183,31.8681,0.59989909,75,59,,2.00E-21,P27473,Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein),Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein),GO:0005737,cytoplasm,PF07534;,,,,,,,,,IFI44_PANTR,Pan troglodytes (Chimpanzee), comp102513_c0_seq1,311,44.6945,0.74286482,3,12,,3.00E-08,Q86UP3,Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4),Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4),GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;,1.00E-14,CHOYP_LOC100877335.1.1,,,,,,,ZFHX4_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp102516_c0_seq1,796,38.4422,0.37865563,18,62,,1.00E-49,Q9QXT1,Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (mDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa),Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (mDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa),GO:0005942; GO:0035014; GO:0005547; GO:0043325; GO:0005886; GO:0043551,"phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; plasma membrane; regulation of phosphatidylinositol 3-kinase activity",PF00169;PF00017;,5.00E-19,CHOYP_LOC100631809.1.2,,,,,,,DAPP1_MOUSE,Mus musculus (Mouse), comp102518_c0_seq1,429,43.5897,0.73951331,11,25,,2.00E-08,Q8IXQ6,Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein),Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein),GO:0003950; GO:0016477; GO:0005737; GO:0005829; GO:0006302; GO:0005634; GO:0060330,NAD+ ADP-ribosyltransferase activity; cell migration; cytoplasm; cytosol; double-strand break repair; nucleus; regulation of response to interferon-gamma,PF01661;,,,,,,,,,PARP9_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330] comp102521_c0_seq2,296,44.9324,0.33582473,0,9,,7.00E-28,O60733,85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9),85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9),GO:0038096; GO:0047499; GO:0035965; GO:0032049; GO:0008219; GO:0005813; GO:0006935; GO:0005829; GO:0007204; GO:0045087; GO:0016042; GO:0060135; GO:0016020; GO:0007613; GO:0005739; GO:0051967; GO:0036151; GO:0036152; GO:0004623; GO:0090238; GO:2000304; GO:0045921; GO:0035774; GO:0090037; GO:0001934; GO:0090200; GO:0045909; GO:1901339; GO:0034976; GO:0014832,"Fc-gamma receptor signaling pathway involved in phagocytosis; calcium-independent phospholipase A2 activity; cardiolipin acyl-chain remodeling; cardiolipin biosynthetic process; cell death; centrosome; chemotaxis; cytosol; elevation of cytosolic calcium ion concentration; innate immune response; lipid catabolic process; maternal process involved in female pregnancy; membrane; memory; mitochondrion; negative regulation of synaptic transmission, glutamatergic; phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; phospholipase A2 activity; positive regulation of arachidonic acid secretion; positive regulation of ceramide biosynthetic process; positive regulation of exocytosis; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of protein kinase C signaling cascade; positive regulation of protein phosphorylation; positive regulation of release of cytochrome c from mitochondria; positive regulation of vasodilation; regulation of store-operated calcium channel activity; response to endoplasmic reticulum stress; urinary bladder smooth muscle contraction",PF12796;PF01734;,,,,,,,,,PLPL9_HUMAN,Homo sapiens (Human),"antibacterial humoral response [GO:0019731]; cardiolipin biosynthetic process [GO:0032049]; chemotaxis [GO:0006935]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lipid catabolic process [GO:0016042]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasodilation [GO:0045909]; regulation of store-operated calcium channel activity [GO:1901339]; response to endoplasmic reticulum stress [GO:0034976]; urinary bladder smooth muscle contraction [GO:0014832]" comp102523_c0_seq1,901,42.3973,0.46051793,48,74,,7.00E-95,Q6PGH0,Ubiquitin domain-containing protein 2,Ubiquitin domain-containing protein 2,GO:0005737; GO:0005634,cytoplasm; nucleus,PF16455;PF00240;,1.00E-64,CHOYP_LOC100372168.1.1,4.00E-88,ruditapes_c12962,,,,,UBTD2_MOUSE,Mus musculus (Mouse), comp102525_c0_seq1,211,41.2322,0.4554345,4,12,,8.00E-24,Q5EBF1,Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II),Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II),GO:0008253; GO:0005737; GO:0046872; GO:0000166; GO:0009117,5'-nucleotidase activity; cytoplasm; metal ion binding; nucleotide binding; nucleotide metabolic process,PF05761;,4.00E-19,CHOYP_LOC100642349.1.1,,,,,,,5NTC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),adenosine metabolic process [GO:0046085]; IMP metabolic process [GO:0046040] comp102526_c0_seq1,470,44.2553,0.83363209,17,35,,3.00E-30,P41828,Nuclear hormone receptor family member nhr-23 (Steroid hormone receptor family member chr-3),Nuclear hormone receptor family member nhr-23 (Steroid hormone receptor family member chr-3),GO:0018996; GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"molting cycle, collagen and cuticulin-based cuticle; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,3.00E-44,CHOYP_DGRI_GH14972.1.1,,,,,,,NHR23_CAEEL,Caenorhabditis elegans,"molting cycle, collagen and cuticulin-based cuticle [GO:0018996]; transcription, DNA-templated [GO:0006351]" comp102536_c0_seq1,390,49.4872,0.63364721,9,0,,6.00E-42,Q80V03,Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),GO:0016021; GO:0005739; GO:0004674,integral to membrane; mitochondrion; protein serine/threonine kinase activity,PF03109;,9.00E-25,CHOYP_ADCK5.1.2,,,,,,,ADCK5_MOUSE,Mus musculus (Mouse), comp102546_c0_seq1,438,39.2694,0.3673147,10,32,,4.00E-16,A7MBC7,Transmembrane protein 194A,Nuclear envelope integral membrane protein 1,GO:0016021,integral to membrane,PF10225;,,,,,,,,,T194A_BOVIN,Bos taurus (Bovine), comp102553_c0_seq1,930,44.5161,0.39113127,19,97,,7.00E-49,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,4.00E-34,CHOYP_DWIL_GK11734.1.1,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp102560_c0_seq1,1099,39.1265,0.60594092,47,106,,4.00E-79,A7MB11,Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1),Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1),GO:0005737; GO:0006886; GO:0005083; GO:0016192,cytoplasm; intracellular protein transport; small GTPase regulator activity; vesicle-mediated transport,PF00637;PF00780;PF10366;PF10367;,3.00E-99,CHOYP_BRAFLDRAFT_268910.1.1,,,,,,,TGFA1_BOVIN,Bos taurus (Bovine),intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp102561_c0_seq1,568,47.5352,0.41694509,5,10,,6.00E-33,Q80TY5,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),GO:0015031,protein transport,PF12624;PF06650;PF16909;,2.00E-28,CHOYP_BRAFLDRAFT_75094.1.2,,,,,,,VP13B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp102564_c0_seq1,739,42.7605,0.68573856,23,17,,2.00E-20,P54254,Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog),Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog),GO:0003677; GO:0008344; GO:0005737; GO:0043569; GO:0042326; GO:0045892; GO:0051168; GO:0042405; GO:0016363; GO:0005654; GO:0034046; GO:0008266; GO:0045944; GO:0008022; GO:0043621; GO:0060079; GO:0006351; GO:0008542,"DNA binding; adult locomotory behavior; cytoplasm; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of phosphorylation; negative regulation of transcription, DNA-dependent; nuclear export; nuclear inclusion body; nuclear matrix; nucleoplasm; poly(G) RNA binding; poly(U) RNA binding; positive regulation of transcription from RNA polymerase II promoter; protein C-terminus binding; protein self-association; regulation of excitatory postsynaptic membrane potential; transcription, DNA-dependent; visual learning",PF12547;PF08517;,3.00E-27,CHOYP_LOC100372922.1.1,,,,,,,ATX1_MOUSE,Mus musculus (Mouse),"adult locomotory behavior [GO:0008344]; excitatory postsynaptic potential [GO:0060079]; lung alveolus development [GO:0048286]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of phosphorylation [GO:0042326]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nuclear export [GO:0051168]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]" comp102583_c0_seq1,660,44.8485,0.64029853,21,31,,3.00E-14,Q8CEF9,Transmembrane protein 132C,Transmembrane protein 132C,GO:0016021; GO:0010923,integral to membrane; negative regulation of phosphatase activity,PF16070;PF15706;PF15705;,4.00E-13,CHOYP_LOC656119.1.1,,,,,,,T132C_MOUSE,Mus musculus (Mouse),negative regulation of phosphatase activity [GO:0010923] comp102585_c0_seq1,644,43.0124,1.12026586,2,72,,4.00E-30,P56489,Muscarinic acetylcholine receptor M1,Muscarinic acetylcholine receptor M1,GO:0016907; GO:0007213; GO:0030054; GO:0050890; GO:0005887; GO:0045211; GO:0040012; GO:0046541,G-protein coupled acetylcholine receptor activity; G-protein coupled acetylcholine receptor signaling pathway; cell junction; cognition; integral to plasma membrane; postsynaptic membrane; regulation of locomotion; saliva secretion,PF00001;,,,,,,,,,ACM1_MACMU,Macaca mulatta (Rhesus macaque),"adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway [GO:0007197]; cognition [GO:0050890]; phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway [GO:0007207]; regulation of locomotion [GO:0040012]; regulation of vascular smooth muscle contraction [GO:0003056]; saliva secretion [GO:0046541]; synaptic transmission, cholinergic [GO:0007271]" comp102644_c0_seq1,757,40.1585,1.05027245,5,125,,3.00E-24,Q61469,Lipid phosphate phosphohydrolase 1 (EC 3.1.3.4) (35 kDa PAP) (mPAP) (Hydrogen peroxide-inducible protein 53) (Hic53) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a),Phospholipid phosphatase 1 (EC 3.1.3.4) (35 kDa PAP) (mPAP) (Hydrogen peroxide-inducible protein 53) (Hic53) (Lipid phosphate phosphohydrolase 1) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a),GO:0006672; GO:0006651; GO:0005887; GO:0008195; GO:0006470; GO:0007165; GO:0006670,ceramide metabolic process; diacylglycerol biosynthetic process; integral to plasma membrane; phosphatidate phosphatase activity; protein dephosphorylation; signal transduction; sphingosine metabolic process,PF01569;,,,,,,,,,LPP1_MOUSE,Mus musculus (Mouse),ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]; sphingosine metabolic process [GO:0006670] comp102694_c1_seq1,828,47.8261,0.42308932,27,25,,,,,,,,,6.00E-18,CHOYP_LOC100367312.6.13,,,,,,,,, comp102705_c0_seq1,207,60.8696,1.31316196,0,6,,8.00E-11,O05313,"Capsular glucan synthase (EC 2.4.1.21) (ADP-glucose--glucan glucosyltransferase) (Alpha-1,4-glucosyltransferase GlgA) (Extracellular alpha-D-glucan synthase)",,GO:0045227; GO:0009250; GO:0009011,capsule polysaccharide biosynthetic process; glucan biosynthetic process; starch synthase activity,,,,,,,,,,GLGA_MYCTU,, comp102729_c0_seq1,389,43.1877,1.12134151,1,24,,8.00E-06,Q03386,Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF),Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF),GO:0008321; GO:0005829; GO:0051056; GO:0007264,Ral guanyl-nucleotide exchange factor activity; cytosol; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00617;PF00618;,,,,,,,,,GNDS_RAT,Rattus norvegicus (Rat),Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] comp102729_c0_seq2,311,45.3376,1.00565101,1,0,,8.00E-07,Q03385,Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF),Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF),GO:0005085; GO:0005622; GO:0051056; GO:0007264,guanyl-nucleotide exchange factor activity; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00617;PF00618;,,,,,,,,,GNDS_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp102745_c0_seq1,513,50.4873,0.43454271,10,47,,8.00E-77,Q7PPU9,Band 7 protein AGAP004871,Band 7 protein AGAP004871,GO:0016021,integral to membrane,PF01145;,8.00E-71,CHOYP_STO2.1.1,8.00E-50,ruditapes_c11694,,,,,BND7A_ANOGA,Anopheles gambiae (African malaria mosquito), comp102747_c1_seq1,341,44.5748,0.24289982,14,0,,1.00E-08,Q6N021,Methylcytosine dioxygenase TET2 (EC 1.14.11.n2),Methylcytosine dioxygenase TET2 (EC 1.14.11.n2),GO:0007049; GO:0080182; GO:0001822; GO:0046872; GO:0070579; GO:0030099; GO:0045944; GO:0009791; GO:0006493,cell cycle; histone H3-K4 trimethylation; kidney development; metal ion binding; methylcytosine dioxygenase activity; myeloid cell differentiation; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein O-linked glycosylation,PF12851;,4.00E-28,CHOYP_TET1.1.1,,,,,,,TET2_HUMAN,Homo sapiens (Human),5-methylcytosine catabolic process [GO:0006211]; cell cycle [GO:0007049]; cytosine metabolic process [GO:0019858]; DNA demethylation [GO:0080111]; hematopoietic stem cell homeostasis [GO:0061484]; hemoglobin metabolic process [GO:0020027]; histone H3-K4 trimethylation [GO:0080182]; kidney development [GO:0001822]; liver morphogenesis [GO:0072576]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein O-linked glycosylation [GO:0006493]; response to organic cyclic compound [GO:0014070]; spleen development [GO:0048536] comp102759_c0_seq1,470,41.0638,0.41681605,2,55,,1.00E-09,Q9UHR6,Zinc finger HIT domain-containing protein 2 (Protein FON),Zinc finger HIT domain-containing protein 2 (Protein FON),GO:0046872,metal ion binding,PF04438;,,,,,,,,,ZNHI2_HUMAN,Homo sapiens (Human), comp102779_c0_seq1,540,45.9259,0.3996119,26,44,,4.00E-28,P42575,Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],GO:0006977; GO:0007568; GO:0097190; GO:0007420; GO:0071260; GO:0004197; GO:0005829; GO:0019899; GO:0097194; GO:0001554; GO:0016020; GO:0005739; GO:0003407; GO:0048011; GO:0005634; GO:0043065; GO:0043525; GO:0016485; GO:0006508; GO:0043281,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; aging; apoptotic signaling pathway; brain development; cellular response to mechanical stimulus; cysteine-type endopeptidase activity; cytosol; enzyme binding; execution phase of apoptosis; luteolysis; membrane; mitochondrion; neural retina development; neurotrophin TRK receptor signaling pathway; nucleus; positive regulation of apoptotic process; positive regulation of neuron apoptotic process; protein processing; proteolysis; regulation of cysteine-type endopeptidase activity involved in apoptotic process",PF00619;,3.00E-39,CHOYP_CASP2.1.5,,,,,,,CASP2_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aging [GO:0007568]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; brain development [GO:0007420]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; ectopic germ cell programmed cell death [GO:0035234]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; luteolysis [GO:0001554]; neural retina development [GO:0003407]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; regulation of apoptotic process [GO:0042981]" comp102787_c0_seq1,781,45.1985,0.35268404,16,56,,3.00E-30,Q58A42,Protein DD3-3,Protein DD3-3,GO:0016021,integral to membrane,,2.00E-30,CHOYP_LOC100372842.1.1,,,,,,,DD3_DICDI,Dictyostelium discoideum (Slime mold), comp102792_c0_seq1,269,46.8401,0.47812449,10,34,,4.00E-10,Q923L3,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_MOUSE,Mus musculus (Mouse),glucose homeostasis [GO:0042593]; startle response [GO:0001964] comp102808_c0_seq2,585,44.7863,0.51247818,14,0,,,,,,,,,2.00E-22,CHOYP_BRAFLDRAFT_80394.4.9,,,,,,,,, comp102811_c0_seq1,1578,38.9734,0.37292554,63,87,,3.00E-19,Q460N3,Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),GO:0003950; GO:0005634; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR15_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp102812_c0_seq2,1108,43.1408,0.61505346,11,15,,3.00E-64,Q8VCR2,17-beta-hydroxysteroid dehydrogenase 13 (17-beta-HSD 13) (EC 1.1.-.-) (Alcohol dehydrogenase PAN1B-like) (Short-chain dehydrogenase/reductase 9),17-beta-hydroxysteroid dehydrogenase 13 (17-beta-HSD 13) (EC 1.1.-.-) (Alcohol dehydrogenase PAN1B-like) (Short-chain dehydrogenase/reductase 9),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF00106;,,,,,,,,,DHB13_MOUSE,Mus musculus (Mouse),positive regulation of lipid biosynthetic process [GO:0046889] comp102812_c0_seq3,959,41.3973,0.49987037,0,7,,2.00E-09,P06235,Nodulation protein G (Host-specificity of nodulation protein C),Nodulation protein G (Host-specificity of nodulation protein C),GO:0009877; GO:0016491,nodulation; oxidoreductase activity,,,,,,,,,,NODG_RHIML,Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti),nodulation [GO:0009877] comp102821_c0_seq1,433,42.9561,0.40823263,17,19,,2.00E-52,Q5SPW0,Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog),Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog),GO:0000938; GO:0040007; GO:0048873; GO:0050881; GO:0060052; GO:0015031; GO:0042147,"GARP complex; growth; homeostasis of number of cells within a tissue; musculoskeletal movement; neurofilament cytoskeleton organization; protein transport; retrograde transport, endosome to Golgi",PF07928;PF10475;,4.00E-49,CHOYP_VPS54.1.1,,,,,,,VPS54_MOUSE,Mus musculus (Mouse),"Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp102833_c0_seq1,411,45.7421,1.00139482,6,25,,2.00E-72,Q2Q1W2,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:0021915; GO:2000637; GO:0051865; GO:0060964; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; neural tube development; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of gene silencing by miRNA; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,,,,,,,,,LIN41_HUMAN,Homo sapiens (Human),3'-UTR-mediated mRNA destabilization [GO:0061158]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] comp102833_c1_seq1,563,43.1616,0.81090219,9,52,,5.00E-21,Q9R1R2,Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1),Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1),GO:0005737; GO:0005769; GO:0015031; GO:0008270,cytoplasm; early endosome; protein transport; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,6.00E-73,CHOYP_LOC100367035.1.1,,,,,,,TRIM3_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; protein ubiquitination [GO:0016567] comp102834_c0_seq1,762,42.9134,1.08543164,8,81,,9.00E-45,Q32KH8,Arylsulfatase H (ASH) (EC 3.1.6.-),Arylsulfatase H (ASH) (EC 3.1.6.-),GO:0016021; GO:0046872; GO:0008484,integral to membrane; metal ion binding; sulfuric ester hydrolase activity,PF00884;,,,,,,,,,ARSH_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),metabolic process [GO:0008152] comp102835_c1_seq1,209,47.8469,1.19953787,0,9,,6.00E-08,Q5SXG7,Vitelline membrane outer layer protein 1 homolog,Vitelline membrane outer layer protein 1 homolog,GO:0005576; GO:0030704,extracellular region; vitelline membrane formation,PF03762;,,,1.00E-11,ruditapes_c35938,,,,,VMO1_MOUSE,Mus musculus (Mouse), comp102842_c0_seq1,303,35.3135,0.53110292,7,24,,3.00E-26,O75626,PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1),GO:0045165; GO:0005737; GO:0001892; GO:0042462; GO:0007281; GO:0001893; GO:0046872; GO:0008168; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0043565; GO:0003700; GO:0006351,"cell fate commitment; cytoplasm; embryonic placenta development; eye photoreceptor cell development; germ cell development; maternal placenta development; metal ion binding; methyltransferase activity; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00856;PF13912;,,,,,,,,,PRDM1_HUMAN,Homo sapiens (Human),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp102853_c1_seq1,385,41.2987,0.73524306,0,21,,9.00E-11,Q9H251,Cadherin-23 (Otocadherin),Cadherin-23 (Otocadherin),GO:0005509; GO:0006816; GO:0016339; GO:0051480; GO:0050957; GO:0007156; GO:0016021; GO:0016020; GO:0045494; GO:0005886; GO:0050896; GO:0050953; GO:0007605; GO:0032420; GO:0007601,calcium ion binding; calcium ion transport; calcium-dependent cell-cell adhesion; cytosolic calcium ion homeostasis; equilibrioception; homophilic cell adhesion; integral to membrane; membrane; photoreceptor cell maintenance; plasma membrane; response to stimulus; sensory perception of light stimulus; sensory perception of sound; stereocilium; visual perception,PF00028;,,,,,,,,,CAD23_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp102859_c0_seq1,406,40.3941,0.60755705,10,31,,9.00E-30,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,3.00E-50,CHOYP_contig_016287,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp10285_c0_seq1,221,42.0814,0.51821789,4,2,,8.00E-34,Q9HCM2,Plexin-A4,Plexin-A4,GO:0021960; GO:0007411; GO:0021793; GO:0021610; GO:0021615; GO:0016021; GO:0005622; GO:0005886; GO:0021784; GO:0048841; GO:0050923; GO:0017154; GO:0002116; GO:0071526; GO:0048485; GO:0021636; GO:0021644,anterior commissure morphogenesis; axon guidance; chemorepulsion of branchiomotor axon; facial nerve morphogenesis; glossopharyngeal nerve morphogenesis; integral to membrane; intracellular; plasma membrane; postganglionic parasympathetic nervous system development; regulation of axon extension involved in axon guidance; regulation of negative chemotaxis; semaphorin receptor activity; semaphorin receptor complex; semaphorin-plexin signaling pathway; sympathetic nervous system development; trigeminal nerve morphogenesis; vagus nerve morphogenesis,PF08337;PF01437;PF01403;PF01833;,3.00E-27,CHOYP_LOC100168635.1.1,,,,,,,PLXA4_HUMAN,Homo sapiens (Human),anterior commissure morphogenesis [GO:0021960]; branchiomotor neuron axon guidance [GO:0021785]; chemorepulsion of branchiomotor axon [GO:0021793]; facial nerve structural organization [GO:0021612]; glossopharyngeal nerve morphogenesis [GO:0021615]; postganglionic parasympathetic fiber development [GO:0021784]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of negative chemotaxis [GO:0050923]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sympathetic nervous system development [GO:0048485]; trigeminal nerve structural organization [GO:0021637]; vagus nerve morphogenesis [GO:0021644] comp102875_c0_seq1,229,71.179,1.2131033,0,5,,9.00E-07,P76214,Protein ves (Various environmental stresses-induced protein),Protein Ves (Various environmental stresses-induced protein),GO:0006950,response to stress,PF05962;,,,,,,,,,VES_ECOLI,Escherichia coli (strain K12), comp102881_c0_seq1,279,44.8029,0.28688893,3,1,,5.00E-33,P42859,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0006888; GO:0051938; GO:0009952; GO:0030424; GO:0008088; GO:0007569; GO:0000052; GO:0016023; GO:0008340; GO:0050809; GO:0007212; GO:0007029; GO:0016197; GO:0007625; GO:0042445; GO:0016234; GO:0030073; GO:0055072; GO:0019244; GO:0007626; GO:0043524; GO:0021990; GO:0051402; GO:0048666; GO:0005634; GO:0021988; GO:0048341; GO:0006606; GO:0019805; GO:0046902; GO:0051881; GO:0048167; GO:0051592; GO:0035176; GO:0007283; GO:0021756; GO:0000050; GO:0047496; GO:0008542,ER to Golgi vesicle-mediated transport; L-glutamate import; anterior/posterior pattern specification; axon; axon cargo transport; cell aging; citrulline metabolic process; cytoplasmic membrane-bounded vesicle; determination of adult lifespan; diazepam binding; dopamine receptor signaling pathway; endoplasmic reticulum organization; endosomal transport; grooming behavior; hormone metabolic process; inclusion body; insulin secretion; iron ion homeostasis; lactate biosynthetic process from pyruvate; locomotory behavior; negative regulation of neuron apoptotic process; neural plate formation; neuron apoptotic process; neuron development; nucleus; olfactory lobe development; paraxial mesoderm formation; protein import into nucleus; quinolinate biosynthetic process; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; regulation of synaptic plasticity; response to calcium ion; social behavior; spermatogenesis; striatum development; urea cycle; vesicle transport along microtubule; visual learning,PF12372;,4.00E-46,CHOYP_HD.1.1,,,,,,,HD_MOUSE,Mus musculus (Mouse),"anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; associative learning [GO:0008306]; axo-dendritic transport [GO:0008088]; brain development [GO:0007420]; cell aging [GO:0007569]; central nervous system development [GO:0007417]; citrulline metabolic process [GO:0000052]; determination of adult lifespan [GO:0008340]; dopamine receptor signaling pathway [GO:0007212]; endoplasmic reticulum organization [GO:0007029]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insulin secretion [GO:0030073]; iron ion homeostasis [GO:0055072]; lactate biosynthetic process from pyruvate [GO:0019244]; learning [GO:0007612]; learning or memory [GO:0007611]; L-glutamate import [GO:0051938]; locomotory behavior [GO:0007626]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; neural plate formation [GO:0021990]; neurogenesis [GO:0022008]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; olfactory lobe development [GO:0021988]; paraxial mesoderm formation [GO:0048341]; peptide hormone secretion [GO:0030072]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein import into nucleus [GO:0006606]; protein localization to centrosome [GO:0071539]; quinolinate biosynthetic process [GO:0019805]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein phosphatase type 2A activity [GO:0034047]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; social behavior [GO:0035176]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; urea cycle [GO:0000050]; vesicle transport along microtubule [GO:0047496]; visual learning [GO:0008542]; vocal learning [GO:0042297]" comp102886_c0_seq1,582,39.3471,0.53372144,20,13,,,,,,,,,,,4.00E-22,ruditapes_c6336,,,,,,, comp102891_c0_seq2,357,62.1849,1.19375082,0,30,,1.00E-13,P50888,60S ribosomal protein L24,60S ribosomal protein L24,GO:0005840,ribosome,PF01246;,,,,,,,,,RL24_HORVU,Hordeum vulgare (Barley), comp102901_c0_seq1,348,42.8161,0.51135953,5,70,,8.00E-13,Q8TCT8,Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2),Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2),GO:0030660; GO:0004190; GO:0071458; GO:0071556; GO:0031902; GO:0005765; GO:0006509; GO:0031293; GO:0005886; GO:0042803; GO:0050776,Golgi-associated vesicle membrane; aspartic-type endopeptidase activity; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; late endosome membrane; lysosomal membrane; membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; plasma membrane; protein homodimerization activity; regulation of immune response,PF02225;PF04258;,,,,,,,,,SPP2A_HUMAN,Homo sapiens (Human),membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; regulation of immune response [GO:0050776]; signal peptide processing [GO:0006465] comp102903_c0_seq1,526,39.924,0.33509068,13,12,,6.00E-37,Q14185,Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),GO:0038096; GO:0005096; GO:0006915; GO:0007411; GO:0007596; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0007229; GO:0016020; GO:0006911; GO:0007264,"Fc-gamma receptor signaling pathway involved in phagocytosis; GTPase activator activity; apoptotic process; axon guidance; blood coagulation; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; integrin-mediated signaling pathway; membrane; phagocytosis, engulfment; small GTPase mediated signal transduction",PF06920;PF14429;PF16172;PF14604;,2.00E-28,CHOYP_DOCK1.2.2,,,,,,,DOCK1_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]" comp102914_c0_seq2,1103,45.3309,0.56582787,4,25,,1.00E-58,Q58EX7,Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1),Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,6.00E-58,CHOYP_LOC100377600.2.2,,,,,,,PKHG4_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; regulation of Rho protein signal transduction [GO:0035023] comp102917_c0_seq1,828,43.2367,0.38809707,15,63,,5.00E-76,Q6P1Z5,PC-esterase domain-containing protein 1A (Protein FAM113A),PC-esterase domain-containing protein 1A (Protein FAM113A),,,PF13839;,4.00E-46,CHOYP_BRAFLDRAFT_126881.2.2,,,,,,,PED1A_MOUSE,Mus musculus (Mouse), comp102917_c0_seq2,463,42.3326,0.3404628,0,0,,,,,,,,,3.00E-25,CHOYP_BRAFLDRAFT_126881.1.2,,,,,,,,, comp102930_c0_seq1,248,36.6935,0.98226449,4,0,,2.00E-11,P35555,Fibrillin-1,Fibrillin-1 [Cleaved into: Asprosin],GO:0005604; GO:0005509; GO:0030198; GO:0005201; GO:0005615; GO:0007507; GO:0001527; GO:0035582; GO:0035583; GO:0001501,basement membrane; calcium ion binding; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; heart development; microfibril; sequestering of BMP in extracellular matrix; sequestering of TGFbeta in extracellular matrix; skeletal system development,PF12662;PF07645;PF00683;,6.00E-12,CHOYP_LOC100637925.1.4,,,,,,,FBN1_HUMAN,Homo sapiens (Human),activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] comp102933_c0_seq2,857,43.2905,0.49122204,3,0,,,,,,,,,2.00E-50,CHOYP_LOC100893093.1.2,,,,,,,,, comp102940_c1_seq1,279,48.0287,0.68858475,0,4,,1.00E-10,O13298,Histone deacetylase phd1 (EC 3.5.1.98),Histone deacetylase phd1 (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0070210; GO:0034967; GO:0006338; GO:0030702; GO:0030466; GO:0006348; GO:0005829; GO:0070932; GO:0034739; GO:0060303; GO:0006357; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); Rpd3L-Expanded complex; Set3 complex; chromatin remodeling; chromatin silencing at centromere; chromatin silencing at silent mating-type cassette; chromatin silencing at telomere; cytosol; histone H3 deacetylation; histone deacetylase activity (H4-K16 specific); regulation of nucleosome density; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00850;,4.00E-21,CHOYP_PHUM_PHUM538580.1.1,,,,,,,PHD1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"heterochromatin assembly involved in chromatin silencing [GO:0070869]; histone deacetylation [GO:0016575]; regulation of nucleosome density [GO:0060303]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp102940_c1_seq2,374,49.4652,0.41088679,5,0,,9.00E-46,Q6P3E7,Histone deacetylase 10 (HD10) (EC 3.5.1.98),Histone deacetylase 10 (HD10) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0000122; GO:0014003; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; negative regulation of transcription from RNA polymerase II promoter; oligodendrocyte development; transcription, DNA-dependent",PF00850;,3.00E-31,CHOYP_LOC100877749.1.1,,,,,,,HDA10_MOUSE,Mus musculus (Mouse),"histone deacetylation [GO:0016575]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oligodendrocyte development [GO:0014003]; protein deacetylation [GO:0006476]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp102991_c0_seq1,361,45.7064,0.80445062,6,21,,5.00E-09,Q68SA9,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS7_MOUSE,Mus musculus (Mouse),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp102991_c1_seq1,423,47.2813,0.64027971,5,39,,2.00E-21,Q8N6G6,ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),GO:0008237; GO:0005578; GO:0008270,metallopeptidase activity; proteinaceous extracellular matrix; zinc ion binding,PF07679;PF08686;PF00090;,,,,,,,,,ATL1_HUMAN,Homo sapiens (Human),protein O-linked fucosylation [GO:0036066] comp103006_c1_seq1,427,43.3255,0.56047926,6,0,,2.00E-08,Q8ZXT3,Uncharacterized protein PAE1111,Uncharacterized protein PAE1111,,,PF01661;,,,,,,,,,Y1111_PYRAE,Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827), comp103007_c0_seq1,1192,45.2181,0.57733297,19,80,,4.00E-65,E1C2V1,Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog),Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog),GO:0016568; GO:0035064; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"chromatin modification; methylated histone residue binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF02820;PF00536;PF01530;,8.00E-25,CHOYP_LMBL3.1.1,,,,,,,LMBL1_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]" comp103010_c0_seq1,610,49.3443,0.37799483,13,72,,3.00E-22,Q8N0X7,Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1),Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1),GO:0009838; GO:0060612; GO:0008219; GO:0051301; GO:0000910; GO:0005811; GO:0034389; GO:0030496; GO:0005741; GO:0030514; GO:0048698; GO:0050905; GO:0051881; GO:0045202,abscission; adipose tissue development; cell death; cell division; cytokinesis; lipid particle; lipid particle organization; midbody; mitochondrial outer membrane; negative regulation of BMP signaling pathway; negative regulation of collateral sprouting in absence of injury; neuromuscular process; regulation of mitochondrial membrane potential; synapse,PF06911;,,,,,,,,,SPG20_HUMAN,Homo sapiens (Human),abscission [GO:0009838]; adipose tissue development [GO:0060612]; cell division [GO:0051301]; lipid particle organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881] comp103034_c0_seq1,532,30.6391,0.88271917,12,79,,3.00E-17,Q24307,Apoptosis 2 inhibitor (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2) (dIAP2),Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2),GO:0050829; GO:0043066; GO:0043154; GO:0061057; GO:0006964; GO:0033160; GO:0070534; GO:0007423; GO:0008270,"defense response to Gram-negative bacterium; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidoglycan recognition protein signaling pathway; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; positive regulation of protein import into nucleus, translocation; protein K63-linked ubiquitination; sensory organ development; zinc ion binding",PF00653;,,,,,,,,,IAP2_DROME,Drosophila melanogaster (Fruit fly),"defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]" comp103081_c0_seq1,212,41.0377,0.5065511,7,18,,1.00E-07,Q80U87,Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),GO:0007265; GO:0007049; GO:0005829; GO:0007032; GO:0031313; GO:0030496; GO:0005634; GO:0005886; GO:0016579; GO:0004221; GO:0006511; GO:0004843,Ras protein signal transduction; cell cycle; cytosol; endosome organization; extrinsic to endosome membrane; midbody; nucleus; plasma membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00581;PF00443;PF08969;,7.00E-16,CHOYP_USP8.1.1,,,,,,,UBP8_MOUSE,Mus musculus (Mouse),endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; ubiquitin-dependent protein catabolic process [GO:0006511] comp103092_c1_seq1,364,44.7802,0.60449116,8,40,,4.00E-10,Q6GNM0,Nurim (Nuclear envelope membrane protein) (Nuclear rim protein),Nurim (Nuclear envelope membrane protein) (Nuclear rim protein),GO:0016021; GO:0005635; GO:0005637,integral to membrane; nuclear envelope; nuclear inner membrane,,,,,,,,,,NRM_XENLA,Xenopus laevis (African clawed frog), comp103100_c0_seq2,214,41.1215,0.69543298,2,0,,5.00E-12,Q6NS57,Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1),Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1),GO:0007256,activation of JNKK activity,PF00400;,2.00E-17,CHOYP_MABP1.2.2,,,,,,,MABP1_MOUSE,Mus musculus (Mouse),activation of JNKK activity [GO:0007256] comp103103_c0_seq1,335,45.0746,0.29536128,2,30,,2.00E-27,Q3SZZ7,Fibrinogen-like protein 1,Fibrinogen-like protein 1,GO:0005576,extracellular region,PF00147;,,,,,,,,,FGL1_BOVIN,Bos taurus (Bovine), comp103130_c0_seq1,227,41.8502,0.85877373,0,0,,2.00E-21,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,,,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp103130_c0_seq2,234,40.5983,0.7665564,4,0,,5.00E-14,Q96J65,Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005739,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrion",PF00664;PF00005;,2.00E-24,CHOYP_MRP4.1.3,,,,,,,MRP9_HUMAN,Homo sapiens (Human), comp103142_c0_seq1,393,41.4758,0.77465716,0,49,,2.00E-27,P08541,UDP-glucuronosyltransferase 2B2 (UDPGT 2B2) (EC 2.4.1.17) (3-hydroxyandrogen-specific UDPGT) (RLUG23) (UDPGTr-4),UDP-glucuronosyltransferase 2B2 (UDPGT 2B2) (EC 2.4.1.17) (3-hydroxyandrogen-specific UDPGT) (RLUG23) (UDPGTr-4),GO:0005789; GO:0015020; GO:0016021,endoplasmic reticulum membrane; glucuronosyltransferase activity; integral to membrane,PF00201;,,,,,,,,,UD2B2_RAT,Rattus norvegicus (Rat),flavonoid biosynthetic process [GO:0009813]; flavonoid glucuronidation [GO:0052696] comp103211_c0_seq1,291,49.1409,0.40864137,16,32,,,,,,,,,4.00E-15,CHOYP_BRAFLDRAFT_230475.2.3,,,,,,,,, comp10321_c0_seq1,206,43.2039,0.96132296,5,0,,4.00E-18,P47990,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0030151; GO:0043546; GO:0005777; GO:0034418; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; peroxisome; urate biosynthetic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,2.00E-22,CHOYP_XDH.2.3,,,,,,,XDH_CHICK,Gallus gallus (Chicken),urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] comp103222_c0_seq1,733,45.1569,0.29596829,10,49,,3.00E-108,O02695,Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.48) (M1851),Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.48) (M1851),GO:0016021; GO:0035335; GO:0004725; GO:0030658,integral to membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; transport vesicle membrane,PF11548;PF14948;PF00102;,3.00E-160,CHOYP_LOC100865286.1.1,,,,,,,PTPR2_MACNE,Macaca nemestrina (Pig-tailed macaque),insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; neurotransmitter secretion [GO:0007269] comp103225_c0_seq1,384,47.6562,0.64613241,7,0,,6.00E-08,A2RSJ4,UHRF1-binding protein 1-like,UHRF1-binding protein 1-like,,,PF12624;,,,,,,,,,UH1BL_MOUSE,Mus musculus (Mouse), comp103246_c0_seq1,233,37.7682,0.48750898,7,14,,,,,,,,,1.00E-26,CHOYP_MKLN1.1.1,,,,,,,,, comp103246_c1_seq1,530,40.1887,0.4811543,17,39,,3.00E-60,Q99PV3,Muskelin,Muskelin,GO:0005737,cytoplasm,PF01344;PF06588;,,,,,,,,,MKLN1_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360] comp103272_c1_seq1,293,47.099,0.98824681,0,33,,1.00E-19,P13002,Protein grainyhead (DNA-binding protein ELF-1) (Element I-binding activity) (Protein grainy-head) (Transcription factor NTF-1),Protein grainyhead (DNA-binding protein ELF-1) (Element I-binding activity) (Protein grainy-head) (Transcription factor NTF-1),GO:0007464; GO:0008362; GO:0003382; GO:0007402; GO:0005634; GO:0007009; GO:0045944; GO:0007428; GO:0042127; GO:0008360; GO:0035159; GO:0061041; GO:0042052; GO:0043565; GO:0003700; GO:0007426; GO:0006351; GO:0007419,"R3/R4 cell fate commitment; chitin-based embryonic cuticle biosynthetic process; epithelial cell morphogenesis; ganglion mother cell fate determination; nucleus; plasma membrane organization; positive regulation of transcription from RNA polymerase II promoter; primary branching, open tracheal system; regulation of cell proliferation; regulation of cell shape; regulation of tube length, open tracheal system; regulation of wound healing; rhabdomere development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tracheal outgrowth, open tracheal system; transcription, DNA-dependent; ventral cord development",PF04516;,7.00E-12,CHOYP_ELF1.1.1,,,,,,,ELF1_DROME,Drosophila melanogaster (Fruit fly),"chitin-based cuticle development [GO:0040003]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; epithelial cell morphogenesis [GO:0003382]; ganglion mother cell fate determination [GO:0007402]; membrane organization [GO:0061024]; nervous system development [GO:0007399]; open tracheal system development [GO:0007424]; plasma membrane organization [GO:0007009]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; primary branching, open tracheal system [GO:0007428]; R3/R4 cell fate commitment [GO:0007464]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of tube architecture, open tracheal system [GO:0035152]; regulation of tube length, open tracheal system [GO:0035159]; regulation of wound healing [GO:0061041]; rhabdomere development [GO:0042052]; tracheal outgrowth, open tracheal system [GO:0007426]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp103276_c1_seq1,348,45.4023,0.56145895,16,26,,4.00E-61,Q86UX6,Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3),Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3),GO:0005524; GO:0046872; GO:0004674,ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00069;,4.00E-54,CHOYP_LOC591895.1.1,,,,,,,ST32C_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] comp103279_c0_seq1,235,48.9362,0.66919926,0,6,,5.00E-18,P29503,Protein neuralized,Protein neuralized,GO:0003677; GO:0008356; GO:0048854; GO:0048749; GO:0005829; GO:0007398; GO:0030718; GO:0007476; GO:0002121; GO:0046331; GO:0031987; GO:0007616; GO:0007498; GO:0005634; GO:0042048; GO:0030707; GO:0048471; GO:0007422; GO:1901981; GO:0005886; GO:0045747; GO:0051260; GO:0008104; GO:0045314; GO:0016360; GO:0001964; GO:0004842; GO:0008270,DNA binding; asymmetric cell division; brain morphogenesis; compound eye development; cytosol; ectoderm development; germ-line stem cell maintenance; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; lateral inhibition; locomotion involved in locomotory behavior; long-term memory; mesoderm development; nucleus; olfactory behavior; ovarian follicle cell development; perinuclear region of cytoplasm; peripheral nervous system development; phosphatidylinositol phosphate binding; plasma membrane; positive regulation of Notch signaling pathway; protein homooligomerization; protein localization; regulation of compound eye photoreceptor development; sensory organ precursor cell fate determination; startle response; ubiquitin-protein ligase activity; zinc ion binding,PF07177;,1.00E-20,CHOYP_AGAP_AGAP001999.1.1,,,,,,,NEUR_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; brain morphogenesis [GO:0048854]; compound eye development [GO:0048749]; ectoderm development [GO:0007398]; germ-line stem cell population maintenance [GO:0030718]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; lateral inhibition [GO:0046331]; locomotion involved in locomotory behavior [GO:0031987]; long-term memory [GO:0007616]; mesoderm development [GO:0007498]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; olfactory behavior [GO:0042048]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; positive regulation of Notch signaling pathway [GO:0045747]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; regulation of compound eye photoreceptor development [GO:0045314]; regulation of Notch signaling pathway [GO:0008593]; regulation of photoreceptor cell differentiation [GO:0046532]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; startle response [GO:0001964]; ventral cord development [GO:0007419] comp103285_c1_seq1,473,41.8605,0.39267029,6,61,,3.00E-50,P17948,Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor),Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor),GO:0005524; GO:0005794; GO:0036326; GO:0036327; GO:0048514; GO:0030154; GO:0048598; GO:0005768; GO:0005615; GO:0005887; GO:0002548; GO:0005634; GO:0001569; GO:0036332; GO:0043406; GO:0045766; GO:0030335; GO:0008284; GO:0043552; GO:0014068; GO:0010863; GO:0030949; GO:0046777; GO:0002040,ATP binding; Golgi apparatus; VEGF-A-activated receptor activity; VEGF-B-activated receptor activity; blood vessel morphogenesis; cell differentiation; embryonic morphogenesis; endosome; extracellular space; integral to plasma membrane; monocyte chemotaxis; nucleus; patterning of blood vessels; placental growth factor-activated receptor activity; positive regulation of MAP kinase activity; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phospholipase C activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein autophosphorylation; sprouting angiogenesis,PF07679;PF00047;PF07714;,5.00E-54,CHOYP_VGFR1.1.1,2.00E-12,ruditapes_c28959,,,,,VGFR1_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; intracellular receptor signaling pathway [GO:0030522]; monocyte chemotaxis [GO:0002548]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; regulation of smooth muscle contraction [GO:0006940]; response to hypoxia [GO:0001666]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp103285_c3_seq1,525,41.3333,0.32434931,15,41,,4.00E-06,P55245,Epidermal growth factor receptor (EC 2.7.10.1) (Fragment),Epidermal growth factor receptor (EC 2.7.10.1),GO:0005524; GO:0000139; GO:0016323; GO:0000902; GO:0008283; GO:0016337; GO:0071392; GO:0021795; GO:0003682; GO:0048546; GO:0001892; GO:0030139; GO:0005789; GO:0005768; GO:0010008; GO:0005006; GO:0001942; GO:0045121; GO:0060571; GO:0043066; GO:0042177; GO:0030235; GO:0031965; GO:0005634; GO:0048471; GO:0045739; GO:0045740; GO:0070374; GO:0043406; GO:0035413; GO:0030335; GO:0031659; GO:0050679; GO:0048146; GO:0045429; GO:0051897; GO:0001934; GO:0045944; GO:0046777; GO:0004713; GO:0050999; GO:0050730; GO:0070141; GO:0007435,ATP binding; Golgi membrane; basolateral plasma membrane; cell morphogenesis; cell proliferation; cell-cell adhesion; cellular response to estradiol stimulus; cerebral cortex cell migration; chromatin binding; digestive tract morphogenesis; embryonic placenta development; endocytic vesicle; endoplasmic reticulum membrane; endosome; endosome membrane; epidermal growth factor-activated receptor activity; hair follicle development; membrane raft; morphogenesis of an epithelial fold; negative regulation of apoptotic process; negative regulation of protein catabolic process; nitric-oxide synthase regulator activity; nuclear membrane; nucleus; perinuclear region of cytoplasm; positive regulation of DNA repair; positive regulation of DNA replication; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAP kinase activity; positive regulation of catenin import into nucleus; positive regulation of cell migration; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of nitric oxide biosynthetic process; positive regulation of protein kinase B signaling cascade; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; protein tyrosine kinase activity; regulation of nitric-oxide synthase activity; regulation of peptidyl-tyrosine phosphorylation; response to UV-A; salivary gland morphogenesis,PF00757;PF14843;PF07714;PF01030;,,,,,,,,,EGFR_MACMU,Macaca mulatta (Rhesus macaque),cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; epidermal growth factor receptor signaling pathway [GO:0007173]; learning or memory [GO:0007611]; positive regulation of cell growth [GO:0030307]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp103293_c0_seq1,1407,45.8422,0.6107933,33,33,,0,P22682,E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (Signal transduction protein CBL),E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (Signal transduction protein CBL),GO:0045453; GO:0005509; GO:0007166; GO:0005737; GO:0043066; GO:0005634; GO:0005886; GO:0014068; GO:0006468; GO:0004871; GO:0004842; GO:0008270,bone resorption; calcium ion binding; cell surface receptor signaling pathway; cytoplasm; negative regulation of apoptotic process; nucleus; plasma membrane; positive regulation of phosphatidylinositol 3-kinase cascade; protein phosphorylation; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF02262;PF02761;PF02762;PF00627;,0,CHOYP_ISCW_ISCW019991.4.5,,,,,,,CBL_MOUSE,Mus musculus (Mouse),bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein phosphorylation [GO:0006468]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp103298_c0_seq1,727,45.8047,0.90946674,7,5,,5.00E-27,Q9Z1L4,Retinoschisin (X-linked juvenile retinoschisis protein homolog),Retinoschisin (X-linked juvenile retinoschisis protein homolog),GO:0016062; GO:0007155; GO:0005576; GO:0019897; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0005546; GO:0070273; GO:0010314; GO:0001786; GO:0010842,"adaptation of rhodopsin mediated signaling; cell adhesion; extracellular region; extrinsic to plasma membrane; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylserine binding; retina layer formation",PF00754;,,,,,,,,,XLRS1_MOUSE,Mus musculus (Mouse),adaptation of rhodopsin mediated signaling [GO:0016062]; cell adhesion [GO:0007155]; retina layer formation [GO:0010842] comp103298_c0_seq2,738,45.122,0.92030057,4,0,,2.00E-23,Q08431,Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin],Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin],GO:0001525; GO:0007155; GO:0009897; GO:0005615; GO:0070062; GO:0019897; GO:0019048; GO:0006911; GO:0006910; GO:0008429; GO:0001786; GO:2000427; GO:0007338,"angiogenesis; cell adhesion; external side of plasma membrane; extracellular space; extracellular vesicular exosome; extrinsic to plasma membrane; modulation by virus of host morphology or physiology; phagocytosis, engulfment; phagocytosis, recognition; phosphatidylethanolamine binding; phosphatidylserine binding; positive regulation of apoptotic cell clearance; single fertilization",PF00008;PF00754;,2.00E-80,CHOYP_SMP_135520.2.2,,,,,,,MFGM_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of cell proliferation [GO:0008284]; response to estrogen [GO:0043627]; single fertilization [GO:0007338]; viral process [GO:0016032]" comp103305_c0_seq1,1203,38.1546,0.27860716,64,78,,4.00E-32,Q9BZE7,UPF0193 protein EVG1,UPF0193 protein EVG1,,,PF05250;,9.00E-37,CHOYP_LOC100372365.2.2,,,,,,,EVG1_HUMAN,Homo sapiens (Human), comp103324_c0_seq1,369,37.1274,0.8674403,0,0,,4.00E-11,Q5EAC5,Zinc finger protein 410,Zinc finger protein 410,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN410_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp103324_c0_seq2,482,36.3071,0.8222927,1,24,,4.00E-13,Q8TF47,Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756),Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756),GO:0003677; GO:0001078; GO:0046872; GO:0043392; GO:0005634; GO:0045893,"DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; metal ion binding; negative regulation of DNA binding; nucleus; positive regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP90_HUMAN,Homo sapiens (Human),"negative regulation of DNA binding [GO:0043392]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp103336_c1_seq1,320,43.4375,0.76429318,0,0,,3.00E-10,Q9WTQ1,Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu),Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu),GO:0005524; GO:0005794; GO:0007030; GO:0048193; GO:0001525; GO:0006915; GO:0005938; GO:0005911; GO:0034599; GO:0035924; GO:0005829; GO:0006954; GO:0045087; GO:0007243; GO:0035556; GO:0046872; GO:0060548; GO:0005634; GO:0018105; GO:0005543; GO:0005886; GO:0032793; GO:0043123; GO:0051092; GO:0045766; GO:0043536; GO:0038033; GO:0010595; GO:0001938; GO:1901727; GO:0010976; GO:0045669; GO:0033138; GO:0045944; GO:0004697; GO:0004674; GO:0010837; GO:0005802,ATP binding; Golgi apparatus; Golgi organization; Golgi vesicle transport; angiogenesis; apoptotic process; cell cortex; cell-cell junction; cellular response to oxidative stress; cellular response to vascular endothelial growth factor stimulus; cytosol; inflammatory response; innate immune response; intracellular protein kinase cascade; intracellular signal transduction; metal ion binding; negative regulation of cell death; nucleus; peptidyl-serine phosphorylation; phospholipid binding; plasma membrane; positive regulation of CREB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of histone deacetylase activity; positive regulation of neuron projection development; positive regulation of osteoblast differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein kinase C activity; protein serine/threonine kinase activity; regulation of keratinocyte proliferation; trans-Golgi network,PF00130;PF00169;PF00069;,,,,,,,,,KPCD1_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of cell death [GO:0060548]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; Ras protein signal transduction [GO:0007265]; regulation of keratinocyte proliferation [GO:0010837]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279] comp103336_c1_seq2,720,44.7222,0.70987062,0,0,,6.00E-66,Q5PU49,Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)],Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)],GO:0005524; GO:0006915; GO:0007049; GO:0042742; GO:0005783; GO:0035556; GO:0016020; GO:0046872; GO:0005739; GO:0030837; GO:0051490; GO:0034351; GO:0090331; GO:0004715; GO:0005634; GO:0048471; GO:0032930; GO:0004697,ATP binding; apoptotic process; cell cycle; defense response to bacterium; endoplasmic reticulum; intracellular signal transduction; membrane; metal ion binding; mitochondrion; negative regulation of actin filament polymerization; negative regulation of filopodium assembly; negative regulation of glial cell apoptotic process; negative regulation of platelet aggregation; non-membrane spanning protein tyrosine kinase activity; nucleus; perinuclear region of cytoplasm; positive regulation of superoxide anion generation; protein kinase C activity,PF00130;PF00069;PF00433;,,,,,,,,,KPCD_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of platelet aggregation [GO:0090331]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of superoxide anion generation [GO:0032930] comp103336_c1_seq3,327,45.8716,0.78153224,0,0,,1.00E-33,P83099,Putative protein kinase C delta type homolog (EC 2.7.11.13),Putative protein kinase C delta type homolog (EC 2.7.11.13),GO:0005524; GO:0035556; GO:0046872; GO:0004697; GO:0004674,ATP binding; intracellular signal transduction; metal ion binding; protein kinase C activity; protein serine/threonine kinase activity,PF00130;PF00069;PF00433;,1.00E-52,CHOYP_LOC100370583.1.1,,,,,,,KPC4_DROME,Drosophila melanogaster (Fruit fly),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468] comp103336_c1_seq4,713,43.6185,0.69643903,0,0,,5.00E-07,Q7TT49,Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta),Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta),GO:0005524; GO:0017048; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0005886; GO:0004674; GO:0005083,ATP binding; Rho GTPase binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;,,,,,,,,,MRCKB_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp103338_c3_seq1,301,66.113,1.13006911,0,24,,4.00E-12,P50360,Uncharacterized protein y4hP,Uncharacterized protein y4hP,,,PF03050;PF13007;PF13005;,,,,,,,,,Y4HP_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234), comp103380_c0_seq1,224,67.4107,1.07776651,0,3,,3.00E-46,Q6A6T4,30S ribosomal protein S9,30S ribosomal protein S9,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00380;,,,,,,,,,RS9_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),translation [GO:0006412] comp103390_c0_seq1,546,43.0403,0.56102752,10,46,,4.00E-66,Q3MHG0,Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4),Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4),GO:0000139; GO:0007030; GO:0017119; GO:0048213; GO:0015031; GO:0006890,"Golgi membrane; Golgi organization; Golgi transport complex; Golgi vesicle prefusion complex stabilization; protein transport; retrograde vesicle-mediated transport, Golgi to ER",PF08318;,3.00E-45,CHOYP_LOC580207.1.1,,,,,,,COG4_BOVIN,Bos taurus (Bovine),"Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp103399_c0_seq1,258,41.4729,0.09049752,3,5,,5.00E-12,A0MQH0,Endoribonuclease Dicer (EC 3.1.26.-),Endoribonuclease Dicer (EC 3.1.26.3),GO:0005524; GO:0008026; GO:0016442; GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0031054; GO:0030422; GO:0004525; GO:0030423,ATP binding; ATP-dependent helicase activity; RISC complex; RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; pre-miRNA processing; production of siRNA involved in RNA interference; ribonuclease III activity; targeting of mRNA for destruction involved in RNA interference,PF03368;PF00271;PF02170;PF04851;PF00636;,,,,,,,,,DICER_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423] comp103423_c0_seq1,556,37.7698,0.70891138,21,80,,1.00E-06,Q6R5N8,Toll-like receptor 13,Toll-like receptor 13,GO:0002755; GO:0005768; GO:0010008; GO:0006954; GO:0045087; GO:0016021; GO:0042803; GO:0019843; GO:0043408; GO:0002237; GO:0009615; GO:0034178; GO:0004888,MyD88-dependent toll-like receptor signaling pathway; endosome; endosome membrane; inflammatory response; innate immune response; integral to membrane; protein homodimerization activity; rRNA binding; regulation of MAPK cascade; response to molecule of bacterial origin; response to virus; toll-like receptor 13 signaling pathway; transmembrane signaling receptor activity,PF00560;PF13855;PF01582;,,,,,,,,,TLR13_MOUSE,Mus musculus (Mouse),defense response to other organism [GO:0098542]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; regulation of MAPK cascade [GO:0043408]; response to virus [GO:0009615]; toll-like receptor 13 signaling pathway [GO:0034178] comp103468_c0_seq1,219,40.1826,0.47009527,3,16,,4.00E-07,Q6NUQ1,RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1),RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1),GO:0031572; GO:0005783; GO:0005789; GO:0015031; GO:0016192,G2 DNA damage checkpoint; endoplasmic reticulum; endoplasmic reticulum membrane; protein transport; vesicle-mediated transport,PF04437;,,,,,,,,,RINT1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of signal transduction involved in mitotic G2 DNA damage checkpoint [GO:1902504]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp103469_c1_seq1,233,40.7725,0.54017615,0,0,,2.00E-12,Q6GQF5,Tetraspanin-33 (Tspan-33),Tetraspanin-33 (Tspan-33),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_XENLA,Xenopus laevis (African clawed frog), comp103469_c1_seq2,518,39.1892,0.51284776,3,37,,2.00E-11,Q68VK5,Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9),Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9),GO:0007155; GO:0008283; GO:0016021,cell adhesion; cell proliferation; integral to membrane,PF00335;,,,2.00E-19,ruditapes_c12325,,,,,TSN5_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604] comp103470_c0_seq1,279,43.3692,0.38251858,0,0,,,,,,,,,2.00E-13,CHOYP_MGAM.1.1,,,,,,,,, comp103470_c0_seq2,331,43.8066,0.38308042,1,5,,5.00E-33,P10253,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase],Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase],GO:0004558; GO:0030246; GO:0060048; GO:0002086; GO:0006006; GO:0005980; GO:0007626; GO:0005765; GO:0007040; GO:0032450; GO:0000023; GO:0046716; GO:0050885; GO:0050884; GO:0002026; GO:0005985; GO:0043587; GO:0043181; GO:0055010,alpha-glucosidase activity; carbohydrate binding; cardiac muscle contraction; diaphragm contraction; glucose metabolic process; glycogen catabolic process; locomotory behavior; lysosomal membrane; lysosome organization; maltose alpha-glucosidase activity; maltose metabolic process; muscle cell cellular homeostasis; neuromuscular process controlling balance; neuromuscular process controlling posture; regulation of the force of heart contraction; sucrose metabolic process; tongue morphogenesis; vacuolar sequestering; ventricular cardiac muscle tissue morphogenesis,PF13802;PF01055;PF16863;PF00088;,,,,,,,,,LYAG_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] comp103474_c0_seq1,499,39.2786,0.32092555,1,18,,3.00E-43,A3KGZ2,2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-),2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-),GO:0031418; GO:0005506; GO:0016706,"L-ascorbic acid binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",,2.00E-14,CHOYP_LOC752784.2.2,,,,,,,OGFD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp103478_c0_seq2,240,44.5833,0.76320818,2,0,,7.00E-32,Q9GZT9,Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20),Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20),GO:0031418; GO:0055008; GO:0005829; GO:0019899; GO:0060347; GO:0005506; GO:0060711; GO:0030821; GO:0051344; GO:0043433; GO:0005634; GO:0032364; GO:0031545; GO:0018401; GO:0045765; GO:0061418; GO:0071731; GO:0060412,L-ascorbic acid binding; cardiac muscle tissue morphogenesis; cytosol; enzyme binding; heart trabecula formation; iron ion binding; labyrinthine layer development; negative regulation of cAMP catabolic process; negative regulation of cyclic-nucleotide phosphodiesterase activity; negative regulation of sequence-specific DNA binding transcription factor activity; nucleus; oxygen homeostasis; peptidyl-proline 4-dioxygenase activity; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; regulation of angiogenesis; regulation of transcription from RNA polymerase II promoter in response to hypoxia; response to nitric oxide; ventricular septum morphogenesis,PF13640;PF01753;,2.00E-17,CHOYP_LOC100377307.1.1,,,,,,,EGLN1_HUMAN,Homo sapiens (Human),cardiac muscle tissue morphogenesis [GO:0055008]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of cAMP catabolic process [GO:0030821]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412] comp103487_c0_seq1,336,42.8571,0.68385346,7,6,,,,,,,,,8.00E-12,CHOYP_TM164.1.1,,,,,,,,, comp103487_c1_seq1,231,42.8571,0.19269464,8,0,,1.00E-25,Q5U3C3,Transmembrane protein 164,Transmembrane protein 164,GO:0016021,integral to membrane,PF14808;,,,,,,,,,TM164_HUMAN,Homo sapiens (Human), comp103523_c0_seq1,872,37.7294,0.51196408,4,0,,,,,,,,,2.00E-24,CHOYP_BRAFLDRAFT_203655.2.2,,,,,,,,, comp103523_c0_seq2,1151,41.7029,0.56153569,7,16,,2.00E-76,Q9Y6F1,Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3),Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3),GO:0006281; GO:0003950; GO:0003824; GO:0005814; GO:0005634; GO:0006471,DNA repair; NAD+ ADP-ribosyltransferase activity; catalytic activity; centriole; nucleus; protein ADP-ribosylation,PF00644;PF02877;PF05406;,7.00E-13,CHOYP_BRAFLDRAFT_203655.1.2,,,,,,,PARP3_HUMAN,Homo sapiens (Human),DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; lagging strand elongation [GO:0006273]; positive regulation of DNA ligation [GO:0051106]; protein ADP-ribosylation [GO:0006471]; protein localization to site of double-strand break [GO:1990166]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723] comp103525_c1_seq1,362,50.5525,0.78102437,14,0,,6.00E-32,Q8CB19,Putative homeodomain transcription factor 2,Putative homeodomain transcription factor 2,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12129;,3.00E-68,CHOYP_PHTF2.1.1,,,,,,,PHTF2_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp103537_c0_seq1,213,54.9296,0.12514896,0,3,,3.00E-09,Q80XJ3,Tetratricopeptide repeat protein 28 (TPR repeat protein 28),Tetratricopeptide repeat protein 28 (TPR repeat protein 28),GO:0051301; GO:0005813; GO:0005737; GO:0030496; GO:0007067; GO:1990023; GO:0097431; GO:0007346,cell division; centrosome; cytoplasm; midbody; mitosis; mitotic spindle midzone; mitotic spindle pole; regulation of mitotic cell cycle,PF12770;PF13176;,,,,,,,,,TTC28_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp103537_c1_seq1,517,51.4507,0.52713901,3,51,,8.00E-10,Q96AY4,Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0000922,cell division; cytoplasm; microtubule organizing center; midbody; mitosis; spindle pole,PF12770;PF13176;PF13181;,6.00E-60,CHOYP_TTC28.1.1,,,,,,,TTC28_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp103543_c1_seq1,282,51.4184,0.10781088,17,0,,8.00E-09,Q8NEZ4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,,,,,,,,,MLL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp103553_c1_seq1,579,40.4145,0.63783181,19,64,,2.00E-23,P46531,Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation; Notch 1 intracellular domain (NICD)],Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)],GO:0000139; GO:0002193; GO:0007220; GO:0061314; GO:0003270; GO:0001190; GO:0042640; GO:0003180; GO:0060842; GO:0003162; GO:0003181; GO:0009912; GO:0007409; GO:0048754; GO:0005509; GO:0003207; GO:0003214; GO:0060038; GO:0003213; GO:0003219; GO:0060948; GO:0001708; GO:0003273; GO:0009986; GO:0071372; GO:0035924; GO:0031490; GO:0072044; GO:0007386; GO:0001047; GO:0060982; GO:0003169; GO:0005829; GO:0072017; GO:0035116; GO:0060956; GO:0003160; GO:0007492; GO:0005789; GO:0019899; GO:0004857; GO:0003198; GO:0005576; GO:0030900; GO:0007440; GO:0010001; GO:0072144; GO:0003241; GO:0031069; GO:0001947; GO:0006959; GO:0006955; GO:0001701; GO:0002437; GO:0016021; GO:0072602; GO:0030216; GO:0070986; GO:0001889; GO:0030324; GO:0003192; GO:0030514; GO:2000811; GO:0045955; GO:0090090; GO:0090051; GO:0010812; GO:2001027; GO:0060253; GO:0045662; GO:0010832; GO:0048715; GO:0030279; GO:0045668; GO:0046533; GO:2000974; GO:2000737; GO:0000122; GO:0021915; GO:0097150; GO:0005654; GO:0003344; GO:0005886; GO:0030513; GO:0046427; GO:0043065; GO:0048711; GO:0060045; GO:0030335; GO:0050679; GO:0010718; GO:0045618; GO:0061419; GO:0007221; GO:0060740; GO:0003184; GO:0004872; GO:0060768; GO:1901201; GO:0014807; GO:0003256; GO:0032495; GO:0060528; GO:0043565; GO:0003700; GO:0035914; GO:0048103; GO:0002040; GO:0006367; GO:0035148; GO:0060979; GO:0060843; GO:0060412; GO:0003222,Golgi membrane; MAML1-RBP-Jkappa- ICN1 complex; Notch receptor processing; Notch signaling involved in heart development; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; anagen; aortic valve morphogenesis; arterial endothelial cell differentiation; atrioventricular node development; atrioventricular valve morphogenesis; auditory receptor cell fate commitment; axonogenesis; branching morphogenesis of an epithelial tube; calcium ion binding; cardiac chamber formation; cardiac left ventricle morphogenesis; cardiac muscle cell proliferation; cardiac right atrium morphogenesis; cardiac right ventricle formation; cardiac vascular smooth muscle cell development; cell fate specification; cell migration involved in endocardial cushion formation; cell surface; cellular response to follicle-stimulating hormone stimulus; cellular response to vascular endothelial growth factor stimulus; chromatin DNA binding; collecting duct development; compartment pattern specification; core promoter binding; coronary artery morphogenesis; coronary vein morphogenesis; cytosol; distal tubule development; embryonic hindlimb morphogenesis; endocardial cell differentiation; endocardium morphogenesis; endoderm development; endoplasmic reticulum membrane; enzyme binding; enzyme inhibitor activity; epithelial to mesenchymal transition involved in endocardial cushion formation; extracellular region; forebrain development; foregut morphogenesis; glial cell differentiation; glomerular mesangial cell development; growth involved in heart morphogenesis; hair follicle morphogenesis; heart looping; humoral immune response; immune response; in utero embryonic development; inflammatory response to antigenic stimulus; integral to membrane; interleukin-4 secretion; keratinocyte differentiation; left/right axis specification; liver development; lung development; mitral valve formation; negative regulation of BMP signaling pathway; negative regulation of anoikis; negative regulation of calcium ion-dependent exocytosis; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cell migration involved in sprouting angiogenesis; negative regulation of cell-substrate adhesion; negative regulation of endothelial cell chemotaxis; negative regulation of glial cell proliferation; negative regulation of myoblast differentiation; negative regulation of myotube differentiation; negative regulation of oligodendrocyte differentiation; negative regulation of ossification; negative regulation of osteoblast differentiation; negative regulation of photoreceptor cell differentiation; negative regulation of pro-B cell differentiation; negative regulation of stem cell differentiation; negative regulation of transcription from RNA polymerase II promoter; neural tube development; neuronal stem cell maintenance; nucleoplasm; pericardium morphogenesis; plasma membrane; positive regulation of BMP signaling pathway; positive regulation of JAK-STAT cascade; positive regulation of apoptotic process; positive regulation of astrocyte differentiation; positive regulation of cardiac muscle cell proliferation; positive regulation of cell migration; positive regulation of epithelial cell proliferation; positive regulation of epithelial to mesenchymal transition; positive regulation of keratinocyte differentiation; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; positive regulation of transcription of Notch receptor target; prostate gland epithelium morphogenesis; pulmonary valve morphogenesis; receptor activity; regulation of epithelial cell proliferation involved in prostate gland development; regulation of extracellular matrix assembly; regulation of somitogenesis; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; response to muramyl dipeptide; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; somatic stem cell division; sprouting angiogenesis; transcription initiation from RNA polymerase II promoter; tube formation; vasculogenesis involved in coronary vascular morphogenesis; venous endothelial cell differentiation; ventricular septum morphogenesis; ventricular trabecula myocardium morphogenesis,PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,6.00E-16,CHOYP_LOC100897243.1.1,,,,,,,NOTC1_HUMAN,Homo sapiens (Human),"aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium morphogenesis [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of auditory receptor cell differentiation [GO:0045608]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; organ regeneration [GO:0031100]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]" comp103568_c1_seq1,447,42.0582,0.15789553,14,34,,2.00E-08,Q5H8C4,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),GO:0031045; GO:0007626; GO:0007399; GO:0015031; GO:0035176,dense core granule; locomotory behavior; nervous system development; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp103578_c0_seq3,1024,45.9961,0.19103906,7,28,,3.00E-131,Q9YH58,Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)],Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)],GO:0005794; GO:0005814; GO:0005542; GO:0030412; GO:0030409; GO:0019556; GO:0019557; GO:0035999,Golgi apparatus; centriole; folic acid binding; formimidoyltetrahydrofolate cyclodeaminase activity; glutamate formimidoyltransferase activity; histidine catabolic process to glutamate and formamide; histidine catabolic process to glutamate and formate; tetrahydrofolate interconversion,PF02971;PF04961;PF07837;,1.00E-123,CHOYP_BRAFLDRAFT_125780.1.1,,,,,,,FTCD_CHICK,Gallus gallus (Chicken),histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999] comp103593_c0_seq1,216,39.3519,0.48063046,0,26,,1.00E-13,Q8BJ64,"Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)","Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)",GO:0008812; GO:0050660; GO:0019285; GO:0005743,choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline; mitochondrial inner membrane,PF05199;PF00732;,1.00E-18,CHOYP_LOC100651467.2.2,,,,,,,CHDH_MOUSE,Mus musculus (Mouse),glycine betaine biosynthetic process from choline [GO:0019285] comp103602_c0_seq2,707,42.0085,0.58512514,23,12,,3.00E-11,Q8N815,Cyclin N-terminal domain-containing protein 1,Cyclin N-terminal domain-containing protein 1,,,PF00134;,,,,,,,,,CNTD1_HUMAN,Homo sapiens (Human),reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283] comp103603_c0_seq1,243,62.963,1.04597107,0,7,,2.00E-52,Q6A661,Protein GrpE (HSP-70 cofactor),Protein GrpE (HSP-70 cofactor),GO:0000774; GO:0005737; GO:0006457; GO:0006950,adenyl-nucleotide exchange factor activity; cytoplasm; protein folding; response to stress,PF01025;,,,,,,,,,GRPE_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),protein folding [GO:0006457] comp103609_c1_seq1,775,43.6129,0.93016196,25,45,,,,,,,,,8.00E-23,CHOYP_NEMVEDRAFT_V1G247129.1.3,,,,,,,,, comp103610_c0_seq1,669,47.3842,1.00895626,19,49,,2.00E-20,P70549,Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0071320; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0042383; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; cellular response to cAMP; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; sarcolemma; telencephalon development,PF03160;PF01699;PF16494;,2.00E-41,CHOYP_LOC100371845.3.3,,,,,,,NAC3_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp103615_c0_seq1,445,43.5955,0.52952237,5,1,,5.00E-41,Q922B6,E3 ubiquitin-protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor-associated factor 7),E3 ubiquitin-protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor-associated factor 7),GO:0000185; GO:0016023; GO:0097194; GO:0005886; GO:0043410; GO:0006355; GO:0006351; GO:0000151; GO:0004842; GO:0008270,"activation of MAPKKK activity; cytoplasmic membrane-bounded vesicle; execution phase of apoptosis; plasma membrane; positive regulation of MAPK cascade; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding",PF00400;PF13445;,9.00E-13,CHOYP_TRAF7.1.1,,,,,,,TRAF7_MOUSE,Mus musculus (Mouse),"activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cellular response to interleukin-6 [GO:0071354]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein sumoylation [GO:0033235]; protein ubiquitination [GO:0016567]; regulation of protein localization [GO:0032880]; transcription, DNA-templated [GO:0006351]" comp103616_c0_seq1,261,57.8544,0.73570754,0,13,,9.00E-23,Q9WYI7,Uncharacterized ABC transporter ATP-binding protein TM_0352,Uncharacterized ABC transporter ATP-binding protein TM_0352,GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;,,,,,,,,,Y352_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),transport [GO:0006810] comp103616_c1_seq1,231,60.6061,1.08988971,1,10,,9.00E-19,Q58903,Uncharacterized ABC transporter ATP-binding protein MJ1508,Uncharacterized ABC transporter ATP-binding protein MJ1508,GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;,,,,,,,,,Y1508_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),transport [GO:0006810] comp103625_c0_seq1,289,44.2907,0.85295139,5,14,,7.00E-06,Q5QD15,Trace amine-associated receptor 4 (TaR-4) (Trace amine receptor 4) (mTaar4) (2-phenylethylamine receptor),Trace amine-associated receptor 4 (TaR-4) (Trace amine receptor 4) (mTaar4) (2-phenylethylamine receptor),GO:1990080; GO:0001662; GO:0007635; GO:0016021; GO:0005886; GO:0007606; GO:0001594,2-phenylethylamine receptor activity; behavioral fear response; chemosensory behavior; integral to membrane; plasma membrane; sensory perception of chemical stimulus; trace-amine receptor activity,PF00001;,,,,,,,,,TAAR4_MOUSE,Mus musculus (Mouse),behavioral fear response [GO:0001662]; chemosensory behavior [GO:0007635]; sensory perception of chemical stimulus [GO:0007606] comp103626_c1_seq1,230,64.7826,1.11348045,0,19,,7.00E-24,Q01326,Ornithine carbamoyltransferase (OTCase) (EC 2.1.3.3) (Fragment),Ornithine carbamoyltransferase (OTCase) (EC 2.1.3.3) (Fragment),GO:0016597; GO:0006526; GO:0005737; GO:0004585; GO:0006591,amino acid binding; arginine biosynthetic process; cytoplasm; ornithine carbamoyltransferase activity; ornithine metabolic process,PF00185;PF02729;,,,,,,,,,OTC_NEIMU,Neisseria mucosa,arginine biosynthetic process [GO:0006526] comp103628_c0_seq1,290,46.2069,0.26789732,4,11,,5.00E-07,P20333,"Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]","Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]",GO:0050779; GO:0071363; GO:0071222; GO:0005576; GO:0006955; GO:0006954; GO:0016021; GO:0045121; GO:0050728; GO:0043025; GO:0005634; GO:0048471; GO:0005886; GO:0051044; GO:0005031; GO:0043196,RNA destabilization; cellular response to growth factor stimulus; cellular response to lipopolysaccharide; extracellular region; immune response; inflammatory response; integral to membrane; membrane raft; negative regulation of inflammatory response; neuronal cell body; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of membrane protein ectodomain proteolysis; tumor necrosis factor-activated receptor activity; varicosity,PF00020;,,,,,,,,,TNR1B_HUMAN,Homo sapiens (Human),aging [GO:0007568]; apoptotic signaling pathway [GO:0097190]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipopolysaccharide [GO:0071222]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism development [GO:0007275]; negative regulation of inflammatory response [GO:0050728]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; RNA destabilization [GO:0050779]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp103633_c0_seq1,270,41.8519,0.16980183,1,13,,2.00E-25,Q93008,"Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)","Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)",GO:0030509; GO:0045177; GO:0051301; GO:0007059; GO:0004197; GO:0005829; GO:0007292; GO:0007067; GO:0000122; GO:0016579; GO:0006367; GO:0007179; GO:0004221; GO:0006511,BMP signaling pathway; apical part of cell; cell division; chromosome segregation; cysteine-type endopeptidase activity; cytosol; female gamete generation; mitosis; negative regulation of transcription from RNA polymerase II promoter; protein deubiquitination; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,5.00E-13,CHOYP_BRAFLDRAFT_275724.1.1,,,,,,,USP9X_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular protein metabolic process [GO:0044267]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp103646_c0_seq1,335,44.4776,0.44851658,7,0,,1.00E-12,F7J220,Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),GO:0030659; GO:0045087; GO:0016021; GO:0006909; GO:0005044,cytoplasmic vesicle membrane; innate immune response; integral to membrane; phagocytosis; scavenger receptor activity,PF00530;PF00084;,,,,,,,,,SRCR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),innate immune response [GO:0045087]; phagocytosis [GO:0006909] comp103646_c1_seq1,237,47.6793,1.06331007,9,0,,4.00E-08,Q9UEW3,Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2),Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2),GO:0043277; GO:0007166; GO:0005581; GO:0030666; GO:0045087; GO:0005887; GO:0005044; GO:0008329; GO:0004888,apoptotic cell clearance; cell surface receptor signaling pathway; collagen; endocytic vesicle membrane; innate immune response; integral to plasma membrane; scavenger receptor activity; signaling pattern recognition receptor activity; transmembrane signaling receptor activity,PF01391;PF00530;,,,,,,,,,MARCO_HUMAN,Homo sapiens (Human),apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898] comp103649_c0_seq1,228,58.7719,0.87210459,1,8,,1.00E-16,P36949,D-ribose-binding protein,Ribose import binding protein RbsB,GO:0008643; GO:0005886,carbohydrate transport; plasma membrane,PF13407;,,,,,,,,,RBSB_BACSU,Bacillus subtilis (strain 168), comp103649_c1_seq1,223,54.2601,0.79607943,0,8,,1.00E-09,P39325,ABC transporter periplasmic-binding protein YtfQ,ABC transporter periplasmic-binding protein YtfQ,GO:0005534; GO:0015757; GO:0042597,galactose binding; galactose transport; periplasmic space,PF13407;,,,,,,,,,YTFQ_ECOLI,Escherichia coli (strain K12),galactose transport [GO:0015757] comp103660_c0_seq2,431,40.3712,0.7465478,5,0,,,,,,,,,3.00E-12,CHOYP_PAXB1.2.2,,,,,,,,, comp103671_c2_seq1,352,48.0114,0.24789526,9,8,,2.00E-18,Q9Y6Y1,Calmodulin-binding transcription activator 1,Calmodulin-binding transcription activator 1,GO:0003677; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03859;PF00612;PF01833;,,,,,,,,,CMTA1_HUMAN,Homo sapiens (Human),neuromuscular process controlling balance [GO:0050885]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp103690_c0_seq1,270,34.8148,0.98861365,6,14,,,,,,,,,8.00E-11,CHOYP_LOC100375592.4.6,,,,,,,,, comp103714_c0_seq1,271,40.5904,0.93665187,3,6,,1.00E-23,Q91V87,Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-5),Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-5),GO:0060539; GO:0005007; GO:0003179; GO:0008201; GO:0005887; GO:0008285; GO:0040037; GO:0001571; GO:0001501; GO:0060412,diaphragm development; fibroblast growth factor-activated receptor activity; heart valve morphogenesis; heparin binding; integral to plasma membrane; negative regulation of cell proliferation; negative regulation of fibroblast growth factor receptor signaling pathway; non-tyrosine kinase fibroblast growth factor receptor activity; skeletal system development; ventricular septum morphogenesis,PF07679;,,,,,,,,,FGRL1_MOUSE,Mus musculus (Mouse),cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway [GO:0007166]; diaphragm development [GO:0060539]; heart valve morphogenesis [GO:0003179]; negative regulation of cell proliferation [GO:0008285]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; protein homooligomerization [GO:0051260]; skeletal system development [GO:0001501]; ventricular septum morphogenesis [GO:0060412] comp103721_c1_seq1,341,42.8152,0.58864534,6,4,,8.00E-15,Q3TUF7,YEATS domain-containing protein 2,YEATS domain-containing protein 2,GO:0005671; GO:0043966; GO:0072686; GO:0000122; GO:0005634,Ada2/Gcn5/Ada3 transcription activator complex; histone H3 acetylation; mitotic spindle; negative regulation of transcription from RNA polymerase II promoter; nucleus,PF03366;,2.00E-18,CHOYP_YETS2.1.1,,,,,,,YETS2_MOUSE,Mus musculus (Mouse),"histone H3 acetylation [GO:0043966]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]" comp103762_c0_seq2,477,41.5094,0.6736073,7,17,,1.00E-16,Q8NHG8,E3 ubiquitin-protein ligase ZNRF2 (EC 6.3.2.-) (Protein Ells2) (RING finger protein 202) (Zinc/RING finger protein 2),E3 ubiquitin-protein ligase ZNRF2 (EC 6.3.2.-) (Protein Ells2) (RING finger protein 202) (Zinc/RING finger protein 2),GO:0030054; GO:0010008; GO:0016874; GO:0005765; GO:0042734; GO:0016567; GO:0008270,cell junction; endosome membrane; ligase activity; lysosomal membrane; presynaptic membrane; protein ubiquitination; zinc ion binding,PF13639;,2.00E-20,CHOYP_LOC100367186.1.1,,,,,,,ZNRF2_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209] comp103775_c0_seq2,1362,37.9589,0.43158885,22,19,,2.00E-40,Q9ER41,Torsin-1B (Torsin family 1 member B),Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B),GO:0005524; GO:0051085; GO:0005788; GO:0005635; GO:0071763; GO:0017111; GO:0051260,ATP binding; chaperone mediated protein folding requiring cofactor; endoplasmic reticulum lumen; nuclear envelope; nuclear membrane organization; nucleoside-triphosphatase activity; protein homooligomerization,PF06309;,,,,,,,,,TOR1B_MOUSE,Mus musculus (Mouse),chaperone mediated protein folding requiring cofactor [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein homooligomerization [GO:0051260] comp103784_c0_seq1,347,49.8559,0.98068447,15,15,,8.00E-11,P79098,Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp103784_c1_seq1,219,45.6621,0.98216334,1,18,,,,,,,,,1.00E-20,CHOYP_APN.2.3,,,,,,,,, comp103798_c0_seq1,603,39.1376,1.06664913,7,43,,2.00E-24,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp103802_c1_seq1,281,42.7046,0.54971456,0,20,,4.00E-09,Q5DRA3,Protocadherin gamma-C4 (PCDH-gamma-C4),Protocadherin gamma-C4 (PCDH-gamma-C4),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF15974;,,,,,,,,,PCDGL_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp103803_c0_seq1,310,38.3871,0.53559685,5,16,,1.00E-06,Q5PQM2,Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8),Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8),GO:0005737; GO:0005871; GO:0005874; GO:0003777,cytoplasm; kinesin complex; microtubule; microtubule motor activity,PF13374;,,,,,,,,,KLC4_RAT,Rattus norvegicus (Rat), comp103815_c0_seq1,444,45.9459,0.43107842,11,16,,2.00E-45,Q8IV35,WD repeat-containing protein 49,WD repeat-containing protein 49,,,PF00400;,5.00E-29,CHOYP_LOC579391.1.1,,,,,,,WDR49_HUMAN,Homo sapiens (Human), comp103817_c0_seq1,457,45.733,1.00715161,13,9,,4.00E-23,Q80YE7,Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),GO:0005524; GO:0015629; GO:0005516; GO:0004683; GO:0071346; GO:0005829; GO:0008625; GO:0007243; GO:0043066; GO:1902042; GO:0017148; GO:0046777; GO:0004672; GO:2000310,ATP binding; actin cytoskeleton; calmodulin binding; calmodulin-dependent protein kinase activity; cellular response to interferon-gamma; cytosol; extrinsic apoptotic signaling pathway via death domain receptors; intracellular protein kinase cascade; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of translation; protein autophosphorylation; protein kinase activity; regulation of N-methyl-D-aspartate selective glutamate receptor activity,PF12796;PF00531;PF00069;,,,,,,,,,DAPK1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310] comp103843_c0_seq1,363,43.5262,0.58324429,28,0,,,,,,,,,4.00E-29,CHOYP_MATN1.3.5,,,,,,,,, comp103846_c1_seq1,300,38.6667,0.53943252,0,15,,1.00E-08,Q9ULD5,Zinc finger protein 777,Zinc finger protein 777,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12417;PF01352;PF00096;,,,,,,,,,ZN777_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp103846_c1_seq2,333,38.1381,0.66369203,0,15,,2.00E-11,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp103882_c0_seq2,429,41.7249,0.48496504,1,21,,8.00E-21,Q7SYJ9,Sperm-associated antigen 7 homolog,Sperm-associated antigen 7 homolog,GO:0003676,nucleic acid binding,PF01424;,,,,,,,,,SPAG7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp103885_c0_seq1,232,40.9483,0.42674786,4,0,,6.00E-15,A4IF87,Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase),Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase),GO:0016287; GO:0006650; GO:0005778,glycerone-phosphate O-acyltransferase activity; glycerophospholipid metabolic process; peroxisomal membrane,PF01553;,,,,,,,,,GNPAT_BOVIN,Bos taurus (Bovine),ether lipid biosynthetic process [GO:0008611]; glycerophospholipid metabolic process [GO:0006650] comp103927_c0_seq1,746,43.5657,0.44687805,23,29,,4.00E-57,Q5SYL3,UPF0378 protein KIAA0100,Protein KIAA0100,GO:0005576,extracellular region,PF10351;PF10344;PF10347;,,,,,,,,,K0100_MOUSE,Mus musculus (Mouse), comp103953_c1_seq1,269,39.777,0.67356597,1,14,,1.00E-10,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp103960_c1_seq1,321,41.7445,0.58439769,1,21,,5.00E-14,Q9H091,Zinc finger MYND domain-containing protein 15,Zinc finger MYND domain-containing protein 15,GO:0005737; GO:0046872; GO:0045892; GO:0005634; GO:0007286; GO:0006351,"cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; spermatid development; transcription, DNA-dependent",PF01753;,,,,,,,,,ZMY15_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]" comp104012_c2_seq1,801,46.3171,0.51284814,8,87,,1.00E-27,A2VDU3,Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25),Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25),GO:0005524; GO:0005671; GO:0007252; GO:0008385; GO:0007254; GO:0004709; GO:0000187; GO:0007250; GO:0006915; GO:0043966; GO:0000287; GO:0005886; GO:0043123; GO:0043507; GO:0002726; GO:0032743; GO:0006355; GO:0006351,"ATP binding; Ada2/Gcn5/Ada3 transcription activator complex; I-kappaB phosphorylation; IkappaB kinase complex; JNK cascade; MAP kinase kinase kinase activity; activation of MAPK activity; activation of NF-kappaB-inducing kinase activity; apoptotic process; histone H3 acetylation; magnesium ion binding; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of T cell cytokine production; positive regulation of interleukin-2 production; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07714;,6.00E-12,CHOYP_M3K7.4.4,,,,,,,M3K7_BOVIN,Bos taurus (Bovine),"activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; histone H3 acetylation [GO:0043966]; I-kappaB phosphorylation [GO:0007252]; JNK cascade [GO:0007254]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of T cell cytokine production [GO:0002726]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp104026_c0_seq2,543,41.989,0.65453017,10,10,,7.00E-25,Q9UNE2,Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein),Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein),GO:0005737; GO:0008092; GO:0006887; GO:0042593; GO:0006886; GO:0046872; GO:0045744; GO:0050714; GO:0017158; GO:0042493; GO:0030667; GO:0030658,cytoplasm; cytoskeletal protein binding; exocytosis; glucose homeostasis; intracellular protein transport; metal ion binding; negative regulation of G-protein coupled receptor protein signaling pathway; positive regulation of protein secretion; regulation of calcium ion-dependent exocytosis; response to drug; secretory granule membrane; transport vesicle membrane,PF02318;,2.00E-22,CHOYP_LOC100549486.1.1,,,,,,,RPH3L_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; positive regulation of protein secretion [GO:0050714]; regulation of exocytosis [GO:0017157]; response to drug [GO:0042493]; vesicle fusion [GO:0006906] comp104029_c0_seq1,280,68.9286,0.94276094,0,18,,4.00E-07,P10351,Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus),Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus),GO:0051537; GO:0008762; GO:0006525; GO:0048072; GO:0008340; GO:0009055; GO:0050660; GO:0006650; GO:0005506; GO:0005875; GO:0043546; GO:0005777; GO:0006206; GO:0006568; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; arginine metabolic process; compound eye pigmentation; determination of adult lifespan; electron carrier activity; flavin adenine dinucleotide binding; glycerophospholipid metabolic process; iron ion binding; microtubule associated complex; molybdopterin cofactor binding; peroxisome; pyrimidine nucleobase metabolic process; tryptophan metabolic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_DROME,Drosophila melanogaster (Fruit fly),arginine metabolic process [GO:0006525]; compound eye pigmentation [GO:0048072]; determination of adult lifespan [GO:0008340]; glycerophospholipid metabolic process [GO:0006650]; purine nucleobase metabolic process [GO:0006144]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ethanol [GO:0045471]; tryptophan metabolic process [GO:0006568]; xanthine catabolic process [GO:0009115] comp104030_c0_seq2,765,41.4379,1.01355426,8,95,,5.00E-71,Q3UQ28,Peroxidasin homolog (EC 1.11.1.7),Peroxidasin homolog (EC 1.11.1.7),GO:0005783; GO:0031012; GO:0030198; GO:0005201; GO:0005615; GO:0020037; GO:0042744; GO:0046872; GO:0004601; GO:0005578,endoplasmic reticulum; extracellular matrix; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity; proteinaceous extracellular matrix,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_MOUSE,Mus musculus (Mouse),extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979] comp104037_c0_seq1,421,39.1924,0.31029587,15,15,,8.00E-12,Q08DX0,Sorting nexin-29,Sorting nexin-29,GO:0007154; GO:0035091,cell communication; phosphatidylinositol binding,PF00787;PF02759;,,,,,,,,,SNX29_BOVIN,Bos taurus (Bovine), comp104059_c0_seq1,293,47.4403,0.42662188,6,18,,3.00E-06,Q8CDI6,Coiled-coil domain-containing protein 158,Coiled-coil domain-containing protein 158,,,PF15921;,9.00E-17,CHOYP_LOC100373433.1.1,,,,,,,CD158_MOUSE,Mus musculus (Mouse), comp104060_c0_seq1,492,46.5447,0.49574772,6,39,,2.00E-20,Q6JQN1,Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),GO:0003995; GO:0050660; GO:0016787; GO:0005739; GO:0016772,"acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; hydrolase activity; mitochondrion; transferase activity, transferring phosphorus-containing groups",PF00441;PF02770;PF02771;PF01636;PF13419;,,,,,,,,,ACD10_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp104079_c0_seq1,442,43.8914,0.14126348,10,17,,3.00E-07,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp104089_c0_seq1,219,60.7306,1.10202662,0,9,,4.00E-17,B6EKY5,Autonomous glycyl radical cofactor,Autonomous glycyl radical cofactor,GO:0003824,catalytic activity,PF01228;,,,,,,,,,GRCA_ALISL,Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)),metabolic process [GO:0008152] comp104089_c1_seq1,264,66.6667,1.35079068,0,19,,5.00E-44,P37836,Formate acetyltransferase (EC 2.3.1.54) (Pyruvate formate-lyase) (Fragment),Formate acetyltransferase (EC 2.3.1.54) (Pyruvate formate-lyase) (Fragment),GO:0005737; GO:0008861,cytoplasm; formate C-acetyltransferase activity,PF01228;PF02901;,,,,,,,,,PFL_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),metabolic process [GO:0008152] comp104133_c0_seq1,463,41.4687,0.35431604,13,22,,2.00E-06,Q7S3M5,Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),Palmitoyltransferase akr1 (EC 2.3.1.225) (Ankyrin repeat-containing protein akr1) (Palmitoyltransferase 1),GO:0000139; GO:0031901; GO:0016021; GO:0016746; GO:0008270,"Golgi membrane; early endosome membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,,,,,,,,,AKR1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), comp104133_c1_seq1,511,44.4227,0.55825759,12,39,,4.00E-11,Q8WWX0,Ankyrin repeat and SOCS box protein 5 (ASB-5),Ankyrin repeat and SOCS box protein 5 (ASB-5),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB5_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp104147_c0_seq1,250,34,0.69491699,5,13,,2.00E-23,A2AJ15,"Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)","Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)",GO:0030433; GO:0005509; GO:0005789; GO:0016021; GO:0004571; GO:0006486,"ER-associated protein catabolic process; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; protein glycosylation",PF01532;,7.00E-11,CHOYP_MA1B1.1.1,,,,,,,MA1B1_MOUSE,Mus musculus (Mouse),"endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; protein alpha-1,2-demannosylation [GO:0036508]; trimming of terminal mannose on B branch [GO:0036509]" comp104149_c0_seq1,248,40.3226,0.61331046,0,25,,,,,,,,,1.00E-27,CHOYP_LOC100496973.5.8,5.00E-36,ruditapes_c10657,,,,,,, comp104153_c0_seq1,539,42.115,0.75878481,25,19,,4.00E-31,P0CE10,"Putative uncharacterized protein At4g01020, chloroplastic","ATP-dependent RNA helicase DEAH11, chloroplastic (EC 3.6.4.13)",GO:0005524; GO:0008026; GO:0003723; GO:0009507; GO:0008270,ATP binding; ATP-dependent helicase activity; RNA binding; chloroplast; zinc ion binding,PF00270;PF04408;PF00271;PF01485;PF07717;PF13445;,,,,,,,,,Y4102_ARATH,Arabidopsis thaliana (Mouse-ear cress),RNA processing [GO:0006396] comp104161_c0_seq1,435,39.3103,0.95457538,8,0,,8.00E-21,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp104164_c0_seq1,357,66.1064,1.22567978,0,29,,5.00E-18,Q6CQ83,Heat shock protein SSB,Heat shock protein SSB,GO:0005524; GO:0005737; GO:0006950; GO:0006412,ATP binding; cytoplasm; response to stress; translation,PF00012;,,,,,,,,,HSP75_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),translation [GO:0006412] comp104174_c0_seq1,416,41.3462,0.3272147,54,132,,3.00E-43,P24367,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),GO:0005788; GO:0042277; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum lumen; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,6.00E-40,CHOYP_NEMVEDRAFT_V1G191841.1.1,9.00E-29,ruditapes_lrc28875,,,,,PPIB_CHICK,Gallus gallus (Chicken),chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] comp104189_c1_seq1,241,44.3983,0.17347969,5,0,,1.00E-21,Q5NCX5,Neuralized-like protein 4,Neuralized-like protein 4,GO:0005814,centriole,PF07177;,,,,,,,,,NEUL4_MOUSE,Mus musculus (Mouse), comp104205_c0_seq1,310,60,1.11470694,0,27,,1.00E-10,P71059,Uncharacterized glycosyltransferase EpsJ (EC 2.4.-.-),Uncharacterized glycosyltransferase EpsJ (EC 2.4.-.-),GO:0000271; GO:0016757,"polysaccharide biosynthetic process; transferase activity, transferring glycosyl groups",PF00535;,,,,,,,,,EPSJ_BACSU,Bacillus subtilis (strain 168),polysaccharide biosynthetic process [GO:0000271] comp104213_c0_seq1,302,41.3907,0.41326149,3,0,,4.00E-06,A2AH22,Activating molecule in BECN1-regulated autophagy protein 1,Activating molecule in BECN1-regulated autophagy protein 1,GO:0005776; GO:0006914; GO:0030154; GO:0005737; GO:0031410; GO:0008285; GO:0043524; GO:0021915,autophagic vacuole; autophagy; cell differentiation; cytoplasm; cytoplasmic vesicle; negative regulation of cell proliferation; negative regulation of neuron apoptotic process; neural tube development,,,,,,,,,,AMRA1_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; parkin-mediated mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of mitophagy [GO:1903599]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of autophagosome assembly [GO:2000785] comp104216_c0_seq1,525,48,1.07987817,14,65,,8.00E-06,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp104235_c1_seq1,742,40.7008,0.32793457,26,65,,9.00E-38,Q99LQ1,MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein),MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein),GO:0005671; GO:0005737; GO:0043966; GO:0005730; GO:0005634,Ada2/Gcn5/Ada3 transcription activator complex; cytoplasm; histone H3 acetylation; nucleolus; nucleus,,,,,,,,,,MBIP1_MOUSE,Mus musculus (Mouse),histone H3 acetylation [GO:0043966] comp104248_c0_seq1,340,33.2353,0.53515843,6,35,,5.00E-19,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,6.00E-20,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp104255_c0_seq1,578,41.3495,0.60998918,0,0,,9.00E-14,Q8LL04,RNA polymerase II C-terminal domain phosphatase-like 3 (FCP-like 3) (EC 3.1.3.16) (Carboxyl-terminal phosphatase-like 3) (AtCPL3) (CTD phosphatase-like 3),RNA polymerase II C-terminal domain phosphatase-like 3 (FCP-like 3) (EC 3.1.3.16) (Carboxyl-terminal phosphatase-like 3) (AtCPL3) (CTD phosphatase-like 3),GO:0003723; GO:0046872; GO:0009788; GO:0005634; GO:0004721; GO:0006355; GO:0009651; GO:0006351,"RNA binding; metal ion binding; negative regulation of abscisic acid mediated signaling pathway; nucleus; phosphoprotein phosphatase activity; regulation of transcription, DNA-dependent; response to salt stress; transcription, DNA-dependent",PF03031;PF12738;,,,,,,,,,CPL3_ARATH,Arabidopsis thaliana (Mouse-ear cress),"dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; negative regulation of abscisic acid-activated signaling pathway [GO:0009788]; response to salt stress [GO:0009651]; transcription, DNA-templated [GO:0006351]" comp104255_c0_seq2,1093,40.3477,0.6606836,16,13,,1.00E-85,Q9Y5B0,RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase),RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase),GO:0008420; GO:0003899; GO:0015629; GO:0051301; GO:0005813; GO:0005737; GO:0010458; GO:0030496; GO:0005654; GO:0050434; GO:0006470; GO:0051233; GO:0000922; GO:0006368; GO:0016032,CTD phosphatase activity; DNA-directed RNA polymerase activity; actin cytoskeleton; cell division; centrosome; cytoplasm; exit from mitosis; midbody; nucleoplasm; positive regulation of viral transcription; protein dephosphorylation; spindle midzone; spindle pole; transcription elongation from RNA polymerase II promoter; viral process,PF09309;PF03031;,2.00E-101,CHOYP_PHUM_PHUM378040.1.1,,,,,,,CTDP1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; exit from mitosis [GO:0010458]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; positive regulation of viral transcription [GO:0050434]; protein dephosphorylation [GO:0006470]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366] comp104258_c0_seq1,332,41.8675,0.63228422,5,15,,,,,,,,,8.00E-12,CHOYP_PLCD1.1.1,,,,,,,,, comp104281_c1_seq1,368,46.7391,0.2028881,8,16,,1.00E-52,Q91WF7,"Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)","Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)",GO:0008219; GO:0010008; GO:0007626; GO:0032288; GO:0031642; GO:0048666; GO:0046488; GO:0042578; GO:0043473; GO:0007033,cell death; endosome membrane; locomotory behavior; myelin assembly; negative regulation of myelination; neuron development; phosphatidylinositol metabolic process; phosphoric ester hydrolase activity; pigmentation; vacuole organization,PF02383;,1.00E-67,CHOYP_FIG4.1.2,,,,,,,FIG4_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol metabolic process [GO:0046488]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] comp104283_c1_seq1,283,40.636,0.88862186,0,18,,4.00E-07,Q90953,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp10428_c0_seq1,338,40.2367,0.58701813,7,6,,5.00E-06,Q75Z89,5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),GO:0071886; GO:0070371; GO:0030424; GO:0007610; GO:0005901; GO:0016023; GO:0043198; GO:0008144; GO:0005887; GO:0014065; GO:0006661; GO:0004435; GO:0050795; GO:0046883; GO:0051209; GO:0042493; GO:0051378; GO:0004993; GO:0006939,"1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; ERK1 and ERK2 cascade; axon; behavior; caveola; cytoplasmic membrane-bounded vesicle; dendritic shaft; drug binding; integral to plasma membrane; phosphatidylinositol 3-kinase cascade; phosphatidylinositol biosynthetic process; phosphatidylinositol phospholipase C activity; regulation of behavior; regulation of hormone secretion; release of sequestered calcium ion into cytosol; response to drug; serotonin binding; serotonin receptor activity; smooth muscle contraction",PF00001;,,,,,,,,,5HT2A_BOVIN,Bos taurus (Bovine),activation of phospholipase C activity [GO:0007202]; behavior [GO:0007610]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; protein localization to cytoskeleton [GO:0044380]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; smooth muscle contraction [GO:0006939] comp104309_c0_seq1,396,43.1818,0.54324375,3,0,,3.00E-06,Q5M870,E3 ubiquitin-protein ligase NEURL3 (EC 6.3.2.-) (Lung-inducible neuralized-related C3CH4 RING domain protein) (Neuralized-like protein 3),E3 ubiquitin-protein ligase NEURL3 (EC 6.3.2.-) (Lung-inducible neuralized-related C3CH4 RING domain protein) (Neuralized-like protein 3),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,PF07177;,,,,,,,,,NEUL3_RAT,Rattus norvegicus (Rat), comp104309_c1_seq1,446,45.2915,0.88506533,21,2,,5.00E-57,Q96JN8,Neuralized-like protein 4,Neuralized-like protein 4,GO:0005814,centriole,PF07177;,1.00E-48,CHOYP_NEUL4.2.2,,,,,,,NEUL4_HUMAN,Homo sapiens (Human), comp104333_c0_seq1,233,42.0601,0.68479522,6,3,,6.00E-09,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp104345_c1_seq1,363,40.2204,0.49639964,3,41,,4.00E-34,Q62737,Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox),Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox),GO:0005794; GO:0043020; GO:0016324; GO:0071230; GO:0071480; GO:0071333; GO:0071260; GO:0071407; GO:0071356; GO:0017004; GO:0030425; GO:0009055; GO:0020037; GO:0050665; GO:0006954; GO:0045087; GO:0046872; GO:0005739; GO:0003106; GO:0043025; GO:0055114; GO:0030307; GO:0001938; GO:0045730; GO:0042493; GO:0070555; GO:0031667; GO:0014895; GO:0042554; GO:0016175,Golgi apparatus; NADPH oxidase complex; apical plasma membrane; cellular response to amino acid stimulus; cellular response to gamma radiation; cellular response to glucose stimulus; cellular response to mechanical stimulus; cellular response to organic cyclic compound; cellular response to tumor necrosis factor; cytochrome complex assembly; dendrite; electron carrier activity; heme binding; hydrogen peroxide biosynthetic process; inflammatory response; innate immune response; metal ion binding; mitochondrion; negative regulation of glomerular filtration by angiotensin; neuronal cell body; oxidation-reduction process; positive regulation of cell growth; positive regulation of endothelial cell proliferation; respiratory burst; response to drug; response to interleukin-1; response to nutrient levels; smooth muscle hypertrophy; superoxide anion generation; superoxide-generating NADPH oxidase activity,PF05038;,,,,,,,,,CY24A_RAT,Rattus norvegicus (Rat),cellular response to amino acid stimulus [GO:0071230]; cellular response to angiotensin [GO:1904385]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose stimulus [GO:0071333]; cellular response to L-glutamine [GO:1904845]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cellular response to tumor necrosis factor [GO:0071356]; cytochrome complex assembly [GO:0017004]; hydrogen peroxide biosynthetic process [GO:0050665]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of glomerular filtration by angiotensin [GO:0003106]; oxidation-reduction process [GO:0055114]; positive regulation of cell growth [GO:0030307]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mucus secretion [GO:0070257]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of blood pressure [GO:0008217]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; respiratory burst [GO:0045730]; response to activity [GO:0014823]; response to aldosterone [GO:1904044]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to nutrient levels [GO:0031667]; smooth muscle hypertrophy [GO:0014895]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] comp104352_c0_seq1,205,61.4634,0.9864146,0,12,,1.00E-20,Q46865,mRNA interferase MqsR (EC 3.1.-.-) (Endoribonuclease MqsR) (Motility quorum-sensing regulator MqsR) (Toxin MqsR),mRNA interferase MqsR (EC 3.1.-.-) (Endoribonuclease MqsR) (Motility quorum-sensing regulator MqsR) (Toxin MqsR),GO:0004521; GO:0045892; GO:0017148; GO:0009372; GO:0043488; GO:0044010; GO:0006351,"endoribonuclease activity; negative regulation of transcription, DNA-dependent; negative regulation of translation; quorum sensing; regulation of mRNA stability; single-species biofilm formation; transcription, DNA-dependent",PF15723;,,,,,,,,,MQSR_ECOLI,Escherichia coli (strain K12),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of translation [GO:0017148]; quorum sensing [GO:0009372]; regulation of cell motility [GO:2000145]; regulation of mRNA stability [GO:0043488]; single-species biofilm formation [GO:0044010]; transcription, DNA-templated [GO:0006351]" comp104385_c0_seq1,419,45.1074,1.17608197,12,20,,9.00E-20,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp104401_c0_seq2,616,41.0714,0.58163803,6,11,,6.00E-37,Q8CB44,GRAM domain-containing protein 4 (Death-inducing protein),GRAM domain-containing protein 4 (Death-inducing protein),GO:0006915; GO:0016021; GO:0031966,apoptotic process; integral to membrane; mitochondrial membrane,PF02893;,,,,,,,,,GRAM4_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915] comp104424_c0_seq1,250,49.6,0.46140444,2,22,,1.00E-05,A3KFU9,Patched domain-containing protein 2 (RND-type protein RNDEu-2),Protein dispatched homolog 3 (Patched domain-containing protein 2) (RND-type protein RNDEu-2),GO:0008158; GO:0016021,hedgehog receptor activity; integral to membrane,PF02460;,,,,,,,,,PTHD2_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179] comp104440_c1_seq1,215,44.186,0.38332684,0,7,,1.00E-10,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp104447_c0_seq1,907,41.8964,0.64276893,10,98,,3.00E-81,P91620,"Protein still life, isoforms C/SIF type 2","Protein still life, isoforms C/SIF type 2",GO:0030676; GO:0030054; GO:0035556; GO:0005543; GO:0051491; GO:0005057; GO:0032314; GO:0050770; GO:0050803; GO:0045202,Rac guanyl-nucleotide exchange factor activity; cell junction; intracellular signal transduction; phospholipid binding; positive regulation of filopodium assembly; receptor signaling protein activity; regulation of Rac GTPase activity; regulation of axonogenesis; regulation of synapse structure and activity; synapse,PF00169;PF02196;PF00621;,7.00E-81,CHOYP_AGAP_AGAP006590.1.1,,,,,,,SIF2_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; positive regulation of filopodium assembly [GO:0051491]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synapse structure or activity [GO:0050803] comp104481_c0_seq1,211,40.7583,0.23387177,1,0,,4.00E-16,A2RRV9,Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein),Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein),GO:0051539; GO:0097361; GO:0016226; GO:0046872,"4 iron, 4 sulfur cluster binding; CIA complex; iron-sulfur cluster assembly; metal ion binding",PF02906;PF02256;,,,,,,,,,NARFL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),iron-sulfur cluster assembly [GO:0016226] comp104481_c0_seq2,216,45.8333,0.44286664,0,9,,2.00E-26,A7SDA8,Probable cytosolic Fe-S cluster assembly factor v1g210509,Probable cytosolic Fe-S cluster assembly factor v1g210509,GO:0051539; GO:0016226; GO:0046872,"4 iron, 4 sulfur cluster binding; iron-sulfur cluster assembly; metal ion binding",PF02906;,6.00E-36,CHOYP_BRAFLDRAFT_118961.1.1,,,,,,,NARF_NEMVE,Nematostella vectensis (Starlet sea anemone),iron-sulfur cluster assembly [GO:0016226] comp104494_c1_seq1,359,52.6462,0.64909226,20,15,,6.00E-23,Q5RHP9,Uncharacterized protein C1orf173,Glutamate-rich protein 3,,,PF15257;,2.00E-20,CHOYP_LOC100179357.2.6,,,,,,,CA173_HUMAN,Homo sapiens (Human), comp104501_c0_seq1,202,54.9505,1.05869609,0,3,,5.00E-11,P44023,Uncharacterized protein HI_0594,Uncharacterized protein HI_0594,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF03606;,,,,,,,,,Y594_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),anion transmembrane transport [GO:0098656] comp104503_c0_seq1,208,38.4615,0.40090441,13,0,,1.00E-13,Q14149,MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled-coil domain protein 3),MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3),GO:0005524; GO:0016605; GO:0016235; GO:0007569; GO:0045111; GO:0051457; GO:0048147; GO:0018105; GO:0009791; GO:0050821; GO:0008270,ATP binding; PML body; aggresome; cell aging; intermediate filament cytoskeleton; maintenance of protein location in nucleus; negative regulation of fibroblast proliferation; peptidyl-serine phosphorylation; post-embryonic development; protein stabilization; zinc ion binding,PF07496;,8.00E-22,CHOYP_MORC3.2.2,,,,,,,MORC3_HUMAN,Homo sapiens (Human),cell aging [GO:0007569]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-serine phosphorylation [GO:0018105]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; viral process [GO:0016032] comp104524_c0_seq1,284,60.2113,0.8187516,0,31,,8.00E-26,Q5NRB3,Hydroxylamine reductase (EC 1.7.-.-) (Hybrid-cluster protein) (HCP),Hydroxylamine reductase (EC 1.7.99.1) (Hybrid-cluster protein) (HCP) (Prismane protein),GO:0051539; GO:0005737; GO:0050418; GO:0046872,"4 iron, 4 sulfur cluster binding; cytoplasm; hydroxylamine reductase activity; metal ion binding",PF03063;,,,,,,,,,HCP_ZYMMO,Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4), comp104555_c1_seq1,626,44.8882,0.70077399,25,21,,2.00E-44,Q32LJ4,Tumor protein p63-regulated gene 1-like protein (Mossy fiber terminal-associated vertebrate-specific presynaptic protein) (Protein FAM79A),Tumor protein p63-regulated gene 1-like protein (Mossy fiber terminal-associated vertebrate-specific presynaptic protein) (Protein FAM79A),GO:0030054; GO:0008021,cell junction; synaptic vesicle,PF12456;,6.00E-23,CHOYP_MYS.1.7,,,,,,,TPRGL_BOVIN,Bos taurus (Bovine), comp104560_c0_seq1,305,40.6557,0.56250605,10,5,,2.00E-09,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,2.00E-11,CHOYP_contig_016287,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp104566_c0_seq1,445,58.8764,0.90983732,2,17,,2.00E-11,Q28RA7,Ribonuclease D (RNase D) (EC 3.1.13.5),Ribonuclease D (RNase D) (EC 3.1.13.5),GO:0008408; GO:0005737; GO:0003676; GO:0090305; GO:0000166; GO:0033890; GO:0042780,3'-5' exonuclease activity; cytoplasm; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleotide binding; ribonuclease D activity; tRNA 3'-end processing,PF01612;PF00570;,,,,,,,,,RND_JANSC,Jannaschia sp. (strain CCS1),tRNA 3'-end processing [GO:0042780] comp104574_c0_seq1,384,36.4583,0.31531745,22,0,,,,,,,,,,,1.00E-13,ruditapes_c24074,,,,,,, comp104574_c0_seq2,216,36.5741,0.56364844,4,3,,,,,,,,,,,3.00E-12,ruditapes_c27792,,,,,,, comp104583_c0_seq1,690,47.2464,0.57219331,25,22,,1.00E-08,Q5R633,Zinc finger and BTB domain-containing protein 48,Zinc finger and BTB domain-containing protein 48,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT48_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp104589_c3_seq1,312,43.9103,0.60115854,6,0,,1.00E-08,Q9BXL7,Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1),Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1),GO:0038095; GO:0031295; GO:0050852; GO:0005829; GO:0004385; GO:0045087; GO:0045121; GO:0005886; GO:0030890; GO:0043123; GO:0051092; GO:0042102; GO:0001819; GO:0045086; GO:0045577; GO:0045580; GO:0042981; GO:0045061,Fc-epsilon receptor signaling pathway; T cell costimulation; T cell receptor signaling pathway; cytosol; guanylate kinase activity; innate immune response; membrane raft; plasma membrane; positive regulation of B cell proliferation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell proliferation; positive regulation of cytokine production; positive regulation of interleukin-2 biosynthetic process; regulation of B cell differentiation; regulation of T cell differentiation; regulation of apoptotic process; thymic T cell selection,PF00619;,,,,,,,,,CAR11_HUMAN,Homo sapiens (Human),Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cytokine production [GO:0001819]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of T cell differentiation [GO:0045580]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; thymic T cell selection [GO:0045061] comp104592_c2_seq1,348,44.8276,0.28724517,6,30,,1.00E-24,Q14139,Ubiquitin conjugation factor E4 A,Ubiquitin conjugation factor E4 A (EC 6.3.2.-),GO:0005737; GO:0000209; GO:0000151; GO:0006511; GO:0034450,cytoplasm; protein polyubiquitination; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-ubiquitin ligase activity,PF04564;PF10408;,,,,,,,,,UBE4A_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] comp104602_c0_seq1,694,43.0836,0.46644392,7,67,,3.00E-42,Q96QF7,Acidic repeat-containing protein,Acidic repeat-containing protein,GO:0005634,nucleus,PF10263;,3.00E-21,CHOYP_LOC100878100.1.1,,,,,,,ACRC_HUMAN,Homo sapiens (Human), comp104604_c0_seq1,282,51.773,1.03246306,0,4,,4.00E-36,Q75D00,Actin,Actin,GO:0005524; GO:0006281; GO:0031011; GO:0035267; GO:0000812; GO:0030479; GO:0032432; GO:0000916; GO:0030476; GO:0000142; GO:0034599; GO:0001300; GO:0006897; GO:0016573; GO:0006357; GO:0000011,ATP binding; DNA repair; Ino80 complex; NuA4 histone acetyltransferase complex; Swr1 complex; actin cortical patch; actin filament bundle; actomyosin contractile ring contraction; ascospore wall assembly; cellular bud neck contractile ring; cellular response to oxidative stress; chronological cell aging; endocytosis; histone acetylation; regulation of transcription from RNA polymerase II promoter; vacuole inheritance,PF00022;,1.00E-27,CHOYP_ACT5.1.3,3.00E-20,ruditapes_lrc32388,,,,,ACT_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),actomyosin contractile ring contraction [GO:0000916]; ascospore wall assembly [GO:0030476]; cellular response to oxidative stress [GO:0034599]; chronological cell aging [GO:0001300]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; mitotic actomyosin contractile ring assembly [GO:1903475]; protein secretion [GO:0009306]; regulation of endocytosis [GO:0030100]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; vacuole inheritance [GO:0000011] comp104604_c0_seq2,317,48.5804,1.15938654,2,6,,,,,,,,,3.00E-23,CHOYP_ACT2.1.3,,,,,,,,, comp104616_c0_seq1,206,62.6214,1.2440197,0,8,,1.00E-39,Q6AB77,Na(+)/H(+) antiporter NhaA (Sodium/proton antiporter NhaA),Na(+)/H(+) antiporter NhaA (Sodium/proton antiporter NhaA),GO:0015297; GO:0016021; GO:0005886; GO:0006885; GO:0035725; GO:0015081,antiporter activity; integral to membrane; plasma membrane; regulation of pH; sodium ion transmembrane transport; sodium ion transmembrane transporter activity,PF06965;,,,,,,,,,NHAA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),regulation of pH [GO:0006885] comp104620_c0_seq1,345,45.5072,0.28084652,19,0,,1.00E-15,Q9R0M0,Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog),Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog),GO:0004930; GO:0016055; GO:0005509; GO:0033326; GO:0042384; GO:0003341; GO:0005737; GO:0007156; GO:0016021; GO:0021999; GO:0001764; GO:0007218; GO:0005886; GO:0032880; GO:0006355; GO:0021591,"G-protein coupled receptor activity; Wnt receptor signaling pathway; calcium ion binding; cerebrospinal fluid secretion; cilium assembly; cilium movement; cytoplasm; homophilic cell adhesion; integral to membrane; neural plate anterior/posterior regionalization; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization; regulation of transcription, DNA-dependent; ventricular system development",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR2_MOUSE,Mus musculus (Mouse),"cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0042384]; cilium movement [GO:0003341]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]" comp104622_c0_seq1,329,48.9362,0.62382429,13,6,,1.00E-37,Q6NTN5,Myotubularin-related protein 13 (SET-binding factor 2),Myotubularin-related protein 13 (SET-binding factor 2),GO:0005737; GO:0005085; GO:0016020; GO:0016791; GO:0005543,cytoplasm; guanyl-nucleotide exchange factor activity; membrane; phosphatase activity; phospholipid binding,PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;,1.00E-15,CHOYP_LOC100645183.1.1,,,,,,,MTMRD_XENLA,Xenopus laevis (African clawed frog), comp104632_c0_seq1,413,46.7312,0.50033253,16,11,,8.00E-33,Q09506,Uncharacterized protein C45G9.7,Uncharacterized protein C45G9.7,GO:0030111,regulation of Wnt receptor signaling pathway,PF00595;,1.00E-60,CHOYP_ISCW_ISCW004725.1.1,,,,,,,YQI7_CAEEL,Caenorhabditis elegans,regulation of Wnt signaling pathway [GO:0030111]; Rho protein signal transduction [GO:0007266] comp104634_c0_seq1,504,43.254,0.66728593,7,43,,2.00E-48,Q17RB8,LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191),LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191),GO:0004176; GO:0006508; GO:0008270,ATP-dependent peptidase activity; proteolysis; zinc ion binding,PF02190;PF13445;,1.00E-18,CHOYP_LONRF1.1.1,,,,,,,LONF1_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209] comp104635_c0_seq1,498,38.755,0.37591628,9,33,,2.00E-58,P36609,Neuronal calcium sensor 2 (NCS-2),Neuronal calcium sensor 2 (NCS-2),GO:0005509,calcium ion binding,PF00036;PF13499;,3.00E-82,CHOYP_SMP_158990.1.1,,,,,,,NCS2_CAEEL,Caenorhabditis elegans, comp104645_c0_seq1,309,42.3948,0.44286178,0,13,,5.00E-06,O70535,Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118),Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118),GO:0019955; GO:0016021; GO:0004923; GO:0010656; GO:0048812; GO:0031100; GO:0005886; GO:0046982,cytokine binding; integral to membrane; leukemia inhibitory factor receptor activity; negative regulation of muscle cell apoptotic process; neuron projection morphogenesis; organ regeneration; plasma membrane; protein heterodimerization activity,PF00041;,,,,,,,,,LIFR_RAT,Rattus norvegicus (Rat),negative regulation of muscle cell apoptotic process [GO:0010656]; neuron projection morphogenesis [GO:0048812]; organ regeneration [GO:0031100]; response to organic cyclic compound [GO:0014070] comp104661_c1_seq1,574,44.7735,0.45275728,19,14,,5.00E-31,Q86XA9,HEAT repeat-containing protein 5A,HEAT repeat-containing protein 5A,,,,,,,,,,,,HTR5A_HUMAN,Homo sapiens (Human), comp104663_c0_seq3,384,43.75,0.51204721,1,0,,3.00E-13,Q812E4,Synaptotagmin-like protein 5,Synaptotagmin-like protein 5,GO:0006886; GO:0016020; GO:0046872,intracellular protein transport; membrane; metal ion binding,PF00168;PF02318;,,,,,,,,,SYTL5_RAT,Rattus norvegicus (Rat),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; intracellular protein transport [GO:0006886]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906] comp104675_c0_seq1,457,40.2626,0.54634641,17,23,,5.00E-27,Q923X4,"Glutaredoxin-2, mitochondrial","Glutaredoxin-2, mitochondrial",GO:0051537; GO:0045454; GO:0009055; GO:0046872; GO:0005739; GO:0005634; GO:0015035; GO:0042542; GO:0010033,"2 iron, 2 sulfur cluster binding; cell redox homeostasis; electron carrier activity; metal ion binding; mitochondrion; nucleus; protein disulfide oxidoreductase activity; response to hydrogen peroxide; response to organic substance",PF00462;,,,,,,,,,GLRX2_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033] comp104681_c0_seq1,568,43.838,0.51460108,6,0,,2.00E-10,Q8C428,Transmembrane channel-like protein 7,Transmembrane channel-like protein 7,GO:0016021; GO:0006811,integral to membrane; ion transport,PF07810;,,,,,,,,,TMC7_MOUSE,Mus musculus (Mouse),ion transport [GO:0006811] comp104681_c0_seq3,501,45.1098,0.55057015,2,0,,1.00E-10,Q8C428,Transmembrane channel-like protein 7,Transmembrane channel-like protein 7,GO:0016021; GO:0006811,integral to membrane; ion transport,PF07810;,3.00E-13,CHOYP_LOC578478.1.1,,,,,,,TMC7_MOUSE,Mus musculus (Mouse),ion transport [GO:0006811] comp104708_c0_seq1,492,43.2927,0.48480443,10,45,,1.00E-35,Q9CR24,"Nucleoside diphosphate-linked moiety X motif 8, mitochondrial (Nudix motif 8) (EC 3.6.1.-)",Nucleoside diphosphate-linked moiety X motif 8 (Nudix motif 8) (EC 3.6.1.-),GO:0016787; GO:0046872; GO:0005739,hydrolase activity; metal ion binding; mitochondrion,PF00293;,,,,,,,,,NUDT8_MOUSE,Mus musculus (Mouse), comp104709_c0_seq1,202,41.5842,0.34701705,0,11,,7.00E-18,P21783,Neurogenic locus notch protein homolog (xOTCH),Neurogenic locus notch homolog protein 1 (Notch 1) (xOTCH) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)],GO:0007219; GO:0005509; GO:0030154; GO:0016021; GO:0000122; GO:0007399; GO:0005654; GO:0004872; GO:0050793,Notch signaling pathway; calcium ion binding; cell differentiation; integral to membrane; negative regulation of transcription from RNA polymerase II promoter; nervous system development; nucleoplasm; receptor activity; regulation of developmental process,PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTCH_XENLA,Xenopus laevis (African clawed frog),"angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium morphogenesis [GO:0060271]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; transcription, DNA-templated [GO:0006351]" comp104709_c1_seq1,210,43.8095,0.59944541,5,0,,1.00E-11,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp104710_c0_seq1,344,44.4767,0.29477351,0,32,,7.00E-19,Q6ZVD7,Storkhead-box protein 1 (Winged-helix domain-containing protein),Storkhead-box protein 1 (Winged-helix domain-containing protein),GO:0003677; GO:0005737; GO:0005634,DNA binding; cytoplasm; nucleus,PF10264;,3.00E-24,CHOYP_STOX1.1.1,,,,,,,STOX1_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; cellular response to nitrosative stress [GO:0071500]; inner ear development [GO:0048839]; mitotic nuclear division [GO:0007067]; negative regulation of gene expression [GO:0010629]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of otic vesicle morphogenesis [GO:1904120]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of gene expression [GO:0010468]; regulation of mitochondrial DNA metabolic process [GO:1901858]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of response to oxidative stress [GO:1902882]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription, DNA-templated [GO:0006351]" comp104719_c0_seq1,537,42.6443,0.47125502,17,16,,1.00E-16,Q5U504,Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5),Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5),GO:0007275; GO:0030017,multicellular organismal development; sarcomere,PF07707;PF00651;PF01344;,,,,,,,,,KBTB5_XENLA,Xenopus laevis (African clawed frog),negative regulation of protein ubiquitination [GO:0031397]; skeletal muscle fiber development [GO:0048741] comp104719_c1_seq1,1549,43.06,0.83453522,94,229,,1.00E-36,Q96CT2,Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),,,PF07707;PF00651;PF01344;,,,,,,,,,KLH29_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp104720_c0_seq1,512,43.9453,0.85731666,0,60,,2.00E-31,Q5FVR2,Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase),Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase),GO:0004645; GO:0006206; GO:0006213; GO:0016154; GO:0009032,phosphorylase activity; pyrimidine nucleobase metabolic process; pyrimidine nucleoside metabolic process; pyrimidine-nucleoside phosphorylase activity; thymidine phosphorylase activity,PF02885;PF00591;PF07831;,,,,,,,,,TYPH_RAT,Rattus norvegicus (Rat),pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleotide metabolic process [GO:0006220] comp104743_c0_seq1,332,44.8795,0.48366452,7,11,,5.00E-07,Q4V869,Acyl-CoA-binding domain-containing protein 6,Acyl-CoA-binding domain-containing protein 6,GO:0005737; GO:0000062; GO:0008289,cytoplasm; fatty-acyl-CoA binding; lipid binding,PF00887;PF12796;,,,,,,,,,ACBD6_XENLA,Xenopus laevis (African clawed frog), comp104761_c0_seq1,491,46.6395,0.56301729,19,3,,7.00E-73,Q9NTG7,"NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)","NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)",GO:0003950; GO:0070403; GO:0032041; GO:0009060; GO:0016020; GO:0005759; GO:0005739; GO:0034983; GO:0006471; GO:0008270,NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity (H3-K14 specific); aerobic respiration; membrane; mitochondrial matrix; mitochondrion; peptidyl-lysine deacetylation; protein ADP-ribosylation; zinc ion binding,PF02146;,5.00E-67,CHOYP_LOC100376942.1.1,,,,,,,SIR3_HUMAN,Homo sapiens (Human),aerobic respiration [GO:0009060]; mitochondrion organization [GO:0007005]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; peptidyl-lysine deacetylation [GO:0034983]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476] comp104762_c0_seq1,237,45.9916,0.65340902,0,17,,2.00E-24,Q9BJZ5,RNA-binding protein fusilli,RNA-binding protein fusilli,GO:0008380; GO:0007173; GO:0003729; GO:0006397; GO:0000166; GO:0005634; GO:0043484,RNA splicing; epidermal growth factor receptor signaling pathway; mRNA binding; mRNA processing; nucleotide binding; nucleus; regulation of RNA splicing,,3.00E-47,CHOYP_LOC659398.1.1,,,,,,,FUSIL_DROME,Drosophila melanogaster (Fruit fly),epidermal growth factor receptor signaling pathway [GO:0007173]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] comp104762_c1_seq1,296,46.6216,0.68635237,0,27,,2.00E-15,A8WPC5,RNA-binding protein sym-2 (Synthetic lethal with mec-8 protein 2),RNA-binding protein sym-2 (Synthetic lethal with mec-8 protein 2),GO:0003723; GO:0008380; GO:0006397; GO:0000166; GO:0005634,RNA binding; RNA splicing; mRNA processing; nucleotide binding; nucleus,PF00076;,,,,,,,,,SYM2_CAEBR,Caenorhabditis briggsae,mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp104763_c1_seq1,404,36.1386,0.30606649,7,5,,9.00E-06,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp104770_c0_seq1,939,40.7881,1.15409931,24,18,,1.00E-62,Q3USZ8,Deleted in autism protein 1 homolog (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF),Deleted in autism protein 1 homolog (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF),GO:0030137; GO:0060038; GO:0005615; GO:0014066; GO:0048199,"COPI-coated vesicle; cardiac muscle cell proliferation; extracellular space; regulation of phosphatidylinositol 3-kinase cascade; vesicle targeting, to, from or within Golgi",PF12260;,4.00E-14,CHOYP_DIA1.1.1,,,,,,,DIA1_MOUSE,Mus musculus (Mouse),"cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; vesicle targeting, to, from or within Golgi [GO:0048199]" comp104773_c0_seq1,348,43.6782,0.72822719,4,12,,8.00E-24,A2VDD2,Tctex1 domain-containing protein 1-B (Fragment),Tctex1 domain-containing protein 1-B (Fragment),,,PF03645;,,,,,,,,,TC1DB_XENLA,Xenopus laevis (African clawed frog), comp104789_c0_seq1,407,46.683,0.5919018,14,5,,3.00E-22,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp104793_c0_seq1,575,35.8261,0.44651298,24,19,,5.00E-32,B0BM24,Protein FAM161A,Protein FAM161A,GO:0030030; GO:0005929; GO:0005737; GO:0005932,cell projection organization; cilium; cytoplasm; microtubule basal body,PF10595;,,,,,,,,,F161A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell projection organization [GO:0030030] comp104829_c0_seq1,355,44.2254,0.40919865,3,12,,1.00E-13,Q6INX1,Transmembrane protein 98,Transmembrane protein 98,GO:0016021,integral to membrane,,3.00E-24,CHOYP_TMM98.1.1,,,,,,,TMM98_XENLA,Xenopus laevis (African clawed frog), comp104841_c1_seq1,374,40.9091,0.66138039,9,16,,9.00E-57,P97784,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0007623; GO:0005829; GO:0003690; GO:0005739; GO:0000122; GO:0005654; GO:0000166; GO:0009881; GO:0000988; GO:0018298; GO:0042752; GO:0006351,"DNA photolyase activity; DNA repair; circadian rhythm; cytosol; double-stranded DNA binding; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; nucleotide binding; photoreceptor activity; protein binding transcription factor activity; protein-chromophore linkage; regulation of circadian rhythm; transcription, DNA-dependent",PF00875;PF03441;,8.00E-44,CHOYP_CRY1.2.2,,,,,,,CRY1_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA damage induced protein phosphorylation [GO:0006975]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; transcription, DNA-templated [GO:0006351]" comp104847_c0_seq1,225,54.6667,0.83705357,3,9,,2.00E-32,Q9KIF7,Glycine betaine transport ATP-binding protein OpuAA (EC 3.6.3.32) (Quaternary-amine-transporting ATPase),Glycine betaine transport ATP-binding protein OpuAA (EC 3.6.3.32) (Quaternary-amine-transporting ATPase),GO:0005524; GO:0006200; GO:0031460; GO:0016020; GO:0015418,ATP binding; ATP catabolic process; glycine betaine transport; membrane; quaternary-ammonium-compound-transporting ATPase activity,PF00005;PF00571;,,,,,,,,,OPUAA_LACLA,Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis),amino acid transport [GO:0006865]; glycine betaine transport [GO:0031460] comp104855_c0_seq2,280,42.5,0.17197282,0,0,,8.00E-19,Q6ZVK8,"8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (MutT homolog 3) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18)","8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (MutT homolog 3) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18)",GO:0044717; GO:0044716; GO:0044715; GO:0046712; GO:0005829; GO:0046057; GO:0046067; GO:0000287; GO:0034656,8-hydroxy-dADP phosphatase activity; 8-oxo-GDP phosphatase activity; 8-oxo-dGDP phosphatase activity; GDP catabolic process; cytosol; dADP catabolic process; dGDP catabolic process; magnesium ion binding; nucleobase-containing small molecule catabolic process,PF00293;,,,,,,,,,NUD18_HUMAN,Homo sapiens (Human),dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712]; nucleobase-containing small molecule catabolic process [GO:0034656] comp104857_c0_seq1,321,70.405,1.01378394,0,6,,3.00E-19,Q8X8Q3,Uncharacterized protein YdaM,Uncharacterized protein YdaM,GO:0009190; GO:0035556; GO:0000155; GO:0016849; GO:0023014,cyclic nucleotide biosynthetic process; intracellular signal transduction; phosphorelay sensor kinase activity; phosphorus-oxygen lyase activity; signal transduction by phosphorylation,PF00990;PF08448;,,,,,,,,,YDAM_ECO57,Escherichia coli O157:H7, comp104861_c1_seq1,839,42.5507,0.84512476,15,69,,5.00E-19,Q70EX6,Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter),Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter),GO:0008508; GO:0016021; GO:0043250; GO:0043251,bile acid:sodium symporter activity; integral to membrane; sodium-dependent organic anion transmembrane transporter activity; sodium-dependent organic anion transport,PF01758;,9.00E-86,CHOYP_BRAFLDRAFT_282065.1.2,,,,,,,SOAT_RAT,Rattus norvegicus (Rat),sodium-dependent organic anion transport [GO:0043251] comp104865_c0_seq1,553,47.7396,0.36386553,19,36,,7.00E-67,Q96BY7,Autophagy-related protein 2 homolog B,Autophagy-related protein 2 homolog B,GO:0006914; GO:0005811; GO:0034045,autophagy; lipid particle; pre-autophagosomal structure membrane,PF13329;PF09333;PF12624;,,,,,,,,,ATG2B_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp104868_c0_seq1,578,46.1938,0.52690409,17,6,,4.00E-59,O08688,Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3),Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3),GO:0004198; GO:0009986; GO:0005622; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; cell surface; intracellular; proteolysis,PF01067;PF00648;,2.00E-59,CHOYP_CAPN5.1.1,,,,,,,CAN5_MOUSE,Mus musculus (Mouse),granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508] comp104890_c1_seq1,304,45.3947,0.51423106,4,12,,1.00E-43,Q8CI71,Coiled-coil domain-containing protein 132 (Bcl2-like protein blm),Syndetin (Bcl2-like protein blm) (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50),,,PF10474;PF10475;,2.00E-38,CHOYP_CC132.1.1,,,,,,,CC132_MOUSE,Mus musculus (Mouse),endocytic recycling [GO:0032456]; protein transport [GO:0015031] comp104901_c1_seq1,263,47.5285,0.27428968,6,12,,3.00E-12,A7UA95,Ras-associating and dilute domain-containing protein,Ras-associating and dilute domain-containing protein,GO:0007155; GO:0007275; GO:0007165,cell adhesion; multicellular organismal development; signal transduction,PF01843;PF00595;PF00788;,,,,,,,,,RADIL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; neural crest cell migration [GO:0001755]; signal transduction [GO:0007165] comp104902_c0_seq3,602,46.1794,0.40625112,35,21,,9.00E-60,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,4.00E-94,CHOYP_DNAH5.2.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp104909_c0_seq2,566,43.8163,0.63619762,13,34,,2.00E-46,Q71B07,Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3),Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF10034;,2.00E-41,CHOYP_DPY19L3.1.1,,,,,,,D19L3_MOUSE,Mus musculus (Mouse),protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] comp104914_c0_seq1,360,43.3333,0.37847575,5,0,,1.00E-08,Q6IV56,RING finger protein 141,RING finger protein 141,GO:0008270,zinc ion binding,,,,,,,,,,RN141_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein autoubiquitination [GO:0051865] comp104915_c0_seq1,214,72.4299,0.89674964,0,9,,4.00E-24,A1VMB2,Homoserine kinase (HK) (HSK) (EC 2.7.1.39),Homoserine kinase (HK) (HSK) (EC 2.7.1.39),GO:0005524; GO:0004413; GO:0009088,ATP binding; homoserine kinase activity; threonine biosynthetic process,PF01636;,,,,,,,,,KHSE_POLNA,Polaromonas naphthalenivorans (strain CJ2),threonine biosynthetic process [GO:0009088] comp104925_c1_seq1,264,31.0606,0,11,0,,,,,,,,,1.00E-13,CHOYP_contig_000076,,,,,,,,, comp104932_c0_seq2,471,39.2781,0.72650103,14,95,,1.00E-15,Q7PCJ9,Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2),Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2),GO:0005737; GO:0004145; GO:0009447,cytoplasm; diamine N-acetyltransferase activity; putrescine catabolic process,PF00583;,,,,,,,,,SAT2_PIG,Sus scrofa (Pig),putrescine catabolic process [GO:0009447] comp104940_c0_seq1,346,40.4624,0.85136675,6,14,,6.00E-26,Q2T9Q1,TBC1 domain family member 20,TBC1 domain family member 20,GO:0005097; GO:0016021; GO:0032851,Rab GTPase activator activity; integral to membrane; positive regulation of Rab GTPase activity,PF00566;,,,,,,,,,TBC20_BOVIN,Bos taurus (Bovine),acrosome assembly [GO:0001675]; cargo loading into COPII-coated vesicle [GO:0090110]; Golgi organization [GO:0007030]; lens fiber cell morphogenesis [GO:0070309]; lipid particle organization [GO:0034389]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; seminiferous tubule development [GO:0072520]; virion assembly [GO:0019068] comp104953_c0_seq1,373,41.8231,0.32899603,22,13,,1.00E-15,Q6PHN1,Coiled-coil domain-containing protein 57,Coiled-coil domain-containing protein 57,,,,,,,,,,,,CCD57_MOUSE,Mus musculus (Mouse), comp104973_c1_seq1,756,41.9312,0.6064258,43,23,,1.00E-56,Q14AM7,UPF0472 protein C16orf72 homolog,UPF0472 protein C16orf72 homolog,,,PF15251;,7.00E-23,CHOYP_PHUM_PHUM536560.2.2,2.00E-21,ruditapes_lrc32913,,,,,CP072_MOUSE,Mus musculus (Mouse), comp104978_c0_seq1,361,43.4903,0.59618376,8,10,,5.00E-06,Q05A80,Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (RNA granule protein 140),Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (RNA granule protein 140),GO:0003723; GO:0005739; GO:0030308; GO:0017148; GO:0050775; GO:0061003,RNA binding; mitochondrion; negative regulation of cell growth; negative regulation of translation; positive regulation of dendrite morphogenesis; positive regulation of dendritic spine morphogenesis,PF00386;PF12287;,,,,,,,,,CAPR2_MOUSE,Mus musculus (Mouse),negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp105004_c0_seq1,204,61.2745,1.10387268,0,3,,3.00E-13,Q47SS3,"(2Z,6E)-farnesyl diphosphate synthase (EC 2.5.1.68) (Cis-prenyltransferase) (Short-chain Z-isoprenyl diphosphate synthase) (Z-FPP synthase) (Z-FPPS) (Z-Polyprenyl diphosphate synthase) (Z-isoprenyl diphosphate synthase)","(2Z,6E)-farnesyl diphosphate synthase (EC 2.5.1.68) (Cis-prenyltransferase) (Short-chain Z-isoprenyl diphosphate synthase) (Z-FPP synthase) (Z-FPPS) (Z-Polyprenyl diphosphate synthase) (Z-isoprenyl diphosphate synthase)",GO:0033850; GO:0000287; GO:0004659,Z-farnesyl diphosphate synthase activity; magnesium ion binding; prenyltransferase activity,PF01255;,,,,,,,,,ZFPP_THEFY,Thermobifida fusca (strain YX), comp105008_c0_seq1,279,49.1039,0.60060832,3,0,,4.00E-10,Q9UIW2,Plexin-A1 (Semaphorin receptor NOV),Plexin-A1 (Semaphorin receptor NOV),GO:0007411; GO:0005737; GO:0060666; GO:0016021; GO:0005634; GO:0005886; GO:0017154; GO:0002116,axon guidance; cytoplasm; dichotomous subdivision of terminal units involved in salivary gland branching; integral to membrane; nucleus; plasma membrane; semaphorin receptor activity; semaphorin receptor complex,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA1_HUMAN,Homo sapiens (Human),branchiomotor neuron axon guidance [GO:0021785]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; multicellular organism development [GO:0007275]; neuron projection extension [GO:1990138]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of smooth muscle cell migration [GO:0014910]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp105012_c0_seq1,212,45.283,0.55566454,2,0,,8.00E-17,Q02401,Lactase-phlorizin hydrolase (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)],Lactase-phlorizin hydrolase (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)],GO:0016324; GO:0005903; GO:0005975; GO:0017042; GO:0016021; GO:0000016; GO:0042493; GO:0043627; GO:0045471; GO:0001666; GO:0010040; GO:0010288; GO:0010045; GO:0007584; GO:0042594; GO:0009744; GO:0016740,apical plasma membrane; brush border; carbohydrate metabolic process; glycosylceramidase activity; integral to membrane; lactase activity; response to drug; response to estrogen stimulus; response to ethanol; response to hypoxia; response to iron(II) ion; response to lead ion; response to nickel cation; response to nutrient; response to starvation; response to sucrose stimulus; transferase activity,PF00232;,,,,,,,,,LPH_RAT,Rattus norvegicus (Rat),carbohydrate metabolic process [GO:0005975]; glycosyl compound metabolic process [GO:1901657]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to nickel cation [GO:0010045]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]; response to starvation [GO:0042594]; response to sucrose [GO:0009744] comp105013_c0_seq1,346,45.9538,0.22109137,7,0,,8.00E-15,Q14118,Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)],Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)],GO:0006607; GO:0042169; GO:0003779; GO:0051393; GO:0005604; GO:0060445; GO:0005509; GO:0030054; GO:0009279; GO:0070938; GO:0005737; GO:0007016; GO:0005856; GO:0016011; GO:0016010; GO:0060441; GO:0030198; GO:0005615; GO:0030175; GO:0016021; GO:0030027; GO:0043237; GO:0006509; GO:0045121; GO:0034453; GO:0019048; GO:0002011; GO:0022011; GO:0043409; GO:0030336; GO:0051898; GO:0021682; GO:0033268; GO:0005654; GO:0045211; GO:0009615; GO:0042383; GO:0008307; GO:0015631; GO:0001618,NLS-bearing protein import into nucleus; SH2 domain binding; actin binding; alpha-actinin binding; basement membrane; branching involved in salivary gland morphogenesis; calcium ion binding; cell junction; cell outer membrane; contractile ring; cytoplasm; cytoskeletal anchoring at plasma membrane; cytoskeleton; dystroglycan complex; dystrophin-associated glycoprotein complex; epithelial tube branching involved in lung morphogenesis; extracellular matrix organization; extracellular space; filopodium; integral to membrane; lamellipodium; laminin-1 binding; membrane protein ectodomain proteolysis; membrane raft; microtubule anchoring; modulation by virus of host morphology or physiology; morphogenesis of an epithelial sheet; myelination in peripheral nervous system; negative regulation of MAPK cascade; negative regulation of cell migration; negative regulation of protein kinase B signaling cascade; nerve maturation; node of Ranvier; nucleoplasm; postsynaptic membrane; response to virus; sarcolemma; structural constituent of muscle; tubulin binding; virus receptor activity,PF05454;,,,,,,,,,DAG1_HUMAN,Homo sapiens (Human),basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; protein O-linked glycosylation [GO:0006493]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; response to peptide hormone [GO:0043434] comp105017_c0_seq1,1061,48.8219,0.47809166,58,23,,1.00E-66,Q9P2G9,Kelch-like protein 8,Kelch-like protein 8,GO:0031463; GO:0042787,Cul3-RING ubiquitin ligase complex; protein ubiquitination involved in ubiquitin-dependent protein catabolic process,PF07707;PF00651;PF01344;,8.00E-37,CHOYP_BRAFLDRAFT_207414.1.2,,,,,,,KLHL8_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp105041_c0_seq1,351,48.433,0.29333571,23,0,,2.00E-21,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,5.00E-34,CHOYP_RN213.10.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp105067_c1_seq1,492,45.7317,0.31847677,20,0,,2.00E-33,Q8R104,NAD-dependent protein deacetylase sirtuin-3 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) (mSIR2L3),NAD-dependent protein deacetylase sirtuin-3 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) (mSIR2L3),GO:0070403; GO:0032041; GO:0009060; GO:0016020; GO:0005759; GO:0005739; GO:0034983; GO:0008270,NAD+ binding; NAD-dependent histone deacetylase activity (H3-K14 specific); aerobic respiration; membrane; mitochondrial matrix; mitochondrion; peptidyl-lysine deacetylation; zinc ion binding,PF02146;,7.00E-21,CHOYP_LOC100376942.1.1,,,,,,,SIR3_MOUSE,Mus musculus (Mouse),aerobic respiration [GO:0009060]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; peptidyl-lysine deacetylation [GO:0034983]; protein deacetylation [GO:0006476] comp105101_c1_seq1,346,41.3295,0.49270188,2,3,,6.00E-40,Q566Y9,Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5),Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5),GO:0006888; GO:0034235; GO:0006506; GO:0005794; GO:0005801; GO:0070971; GO:0005793; GO:0033116; GO:0016021; GO:0030145; GO:0008081,ER to Golgi vesicle-mediated transport; GPI anchor binding; GPI anchor biosynthetic process; Golgi apparatus; cis-Golgi network; endoplasmic reticulum exit site; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; manganese ion binding; phosphoric diester hydrolase activity,PF00149;,,,,,,,,,MPPE1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ER to Golgi vesicle-mediated transport [GO:0006888]; GPI anchor biosynthetic process [GO:0006506] comp105101_c1_seq2,253,38.7352,0.10868805,0,0,,,,,,,,,3.00E-28,CHOYP_LOC100351251.1.1,,,,,,,,, comp105105_c3_seq1,291,45.3608,0.43078945,8,0,,6.00E-16,Q12923,Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1),Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1),GO:0005737; GO:0005856; GO:0030027; GO:0005634; GO:0005886; GO:0004725,cytoplasm; cytoskeleton; lamellipodium; nucleus; plasma membrane; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,3.00E-23,CHOYP_PTP.1.1,,,,,,,PTN13_HUMAN,Homo sapiens (Human),peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp105173_c0_seq1,780,46.1538,0.44313526,41,0,,4.00E-51,Q14155,Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85),Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85),GO:0005089; GO:0097190; GO:0005938; GO:0005829; GO:0007173; GO:0005925; GO:0005085; GO:0030027; GO:0030032; GO:0042059; GO:0007399; GO:0043005; GO:0043025; GO:0048011; GO:0005543; GO:0043547; GO:0043065; GO:0043234; GO:0035023; GO:0051056; GO:0001726; GO:0007264,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; cell cortex; cytosol; epidermal growth factor receptor signaling pathway; focal adhesion; guanyl-nucleotide exchange factor activity; lamellipodium; lamellipodium assembly; negative regulation of epidermal growth factor receptor signaling pathway; nervous system development; neuron projection; neuronal cell body; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of GTPase activity; positive regulation of apoptotic process; protein complex; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; ruffle; small GTPase mediated signal transduction,PF00307;PF00169;PF00621;PF07653;,6.00E-56,CHOYP_ARHG7.3.5,,,,,,,ARHG7_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of protein binding [GO:0032092]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp105181_c0_seq1,250,64,0.90558312,0,15,,1.00E-41,P20865,"Chlorophyll a-b binding protein of LHCII type I, chloroplastic (CAB) (LHCP)","Chlorophyll a-b binding protein of LHCII type I, chloroplastic (CAB) (LHCP)",GO:0016168; GO:0009535; GO:0016021; GO:0046872; GO:0009765; GO:0009522; GO:0009523; GO:0018298,"chlorophyll binding; chloroplast thylakoid membrane; integral to membrane; metal ion binding; photosynthesis, light harvesting; photosystem I; photosystem II; protein-chromophore linkage",PF00504;,,,,,,,,,CB2_DUNSA,Dunaliella salina (Green alga),"photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]" comp105189_c0_seq1,256,41.4062,0.09945972,8,11,,5.00E-27,Q9CR50,RING finger and CHY zinc finger domain-containing protein 1 (EC 6.3.2.-) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (Zinc finger protein 363),RING finger and CHY zinc finger domain-containing protein 1 (EC 6.3.2.-) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (Zinc finger protein 363),GO:0005737; GO:0016607; GO:0005634; GO:0032436; GO:0031398; GO:0051865; GO:0042787; GO:0000151; GO:0004842; GO:0008270,cytoplasm; nuclear speck; nucleus; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination; protein autoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding,PF05495;PF13639;,,,,,,,,,ZN363_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp105206_c0_seq1,476,41.8067,0.5384876,17,10,,2.00E-46,A5PJZ2,Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon),Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon),GO:0000165; GO:0016021; GO:0046872; GO:0006470; GO:0004722; GO:0007178,MAPK cascade; integral to membrane; metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity; transmembrane receptor protein serine/threonine kinase signaling pathway,PF00481;,4.00E-30,CHOYP_LOC100377829.2.2,,,,,,,PPM1L_BOVIN,Bos taurus (Bovine),MAPK cascade [GO:0000165]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] comp105239_c1_seq1,495,44.4444,0.51050899,11,50,,3.00E-44,O08914,Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1),Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1),GO:0000139; GO:0047372; GO:0016884; GO:0005789; GO:0017064; GO:0009062; GO:0016021; GO:0031090,"Golgi membrane; acylglycerol lipase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; endoplasmic reticulum membrane; fatty acid amide hydrolase activity; fatty acid catabolic process; integral to membrane; organelle membrane",PF01425;,,,,,,,,,FAAH1_MOUSE,Mus musculus (Mouse),fatty acid catabolic process [GO:0009062] comp105243_c0_seq1,284,59.507,0.96775393,1,12,,2.00E-08,Q58206,Uncharacterized ABC transporter ATP-binding protein MJ0796,Uncharacterized ABC transporter ATP-binding protein MJ0796,GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;,,,,,,,,,Y796_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),transport [GO:0006810] comp105247_c0_seq2,1047,42.1203,0.54089814,32,27,,7.00E-147,Q96ES7,SAGA-associated factor 29 homolog (Coiled-coil domain-containing protein 101),SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29),GO:0005671; GO:0070461; GO:0071169; GO:0043966; GO:0035064; GO:0006355; GO:0006351,"Ada2/Gcn5/Ada3 transcription activator complex; SAGA-type complex; establishment of protein localization to chromatin; histone H3 acetylation; methylated histone residue binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07039;,1.00E-141,CHOYP_BRAFLDRAFT_125533.1.1,,,,,,,SGF29_HUMAN,Homo sapiens (Human),"establishment of protein localization to chromatin [GO:0071169]; histone H3 acetylation [GO:0043966]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp105250_c0_seq1,691,39.508,0.564377,26,37,,2.00E-11,Q5RCM7,DnaJ homolog subfamily C member 16,DnaJ homolog subfamily C member 16,GO:0045454; GO:0016021,cell redox homeostasis; integral to membrane,PF00226;PF00085;,9.00E-15,CHOYP_LOC100863952.1.1,,,,,,,DJC16_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell redox homeostasis [GO:0045454] comp105255_c0_seq1,757,43.7252,0.69414041,28,22,,2.00E-49,Q5ZLW3,Dymeclin,Dymeclin,GO:0005794; GO:0007030; GO:0060348; GO:0005634; GO:0005886,Golgi apparatus; Golgi organization; bone development; nucleus; plasma membrane,,1.00E-63,CHOYP_LOC100374358.1.1,,,,,,,DYM_CHICK,Gallus gallus (Chicken),bone development [GO:0060348]; Golgi organization [GO:0007030] comp105275_c0_seq1,358,55.3073,0.96217636,1,4,,2.00E-48,P34699,DNA polymerase III subunit alpha (EC 2.7.7.7),DNA polymerase III subunit alpha (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0006260; GO:0003887; GO:0005737,3'-5' exonuclease activity; DNA binding; DNA replication; DNA-directed DNA polymerase activity; cytoplasm,PF07733;PF14579;PF02811;PF01336;,,,,,,,,,DPO3A_SACEN,Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338),DNA replication [GO:0006260] comp105276_c0_seq1,297,43.771,0.35956006,9,19,,7.00E-31,Q5RCF3,Cullin-2 (CUL-2),Cullin-2 (CUL-2),GO:0031462; GO:0016567; GO:0006511,Cul2-RING ubiquitin ligase complex; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,,,,,,,,,CUL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp105281_c0_seq1,339,43.6578,0.65994363,0,24,,3.00E-08,Q923L3,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_MOUSE,Mus musculus (Mouse),glucose homeostasis [GO:0042593]; startle response [GO:0001964] comp105281_c1_seq1,435,42.5287,1.0738973,2,30,,3.00E-08,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp105287_c0_seq1,437,42.5629,0.73986874,19,80,,1.00E-52,P46825,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0005737; GO:0005871; GO:0005874; GO:0003777,cytoplasm; kinesin complex; microtubule; microtubule motor activity,PF13374;,4.00E-55,CHOYP_KLC.2.3,,,,,,,KLC_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp105335_c0_seq1,571,40.8056,0.60210711,18,27,,1.00E-17,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp105350_c0_seq1,708,44.3503,0.37394589,12,43,,7.00E-58,Q7Z392,Trafficking protein particle complex subunit 11,Trafficking protein particle complex subunit 11,GO:0005794; GO:0016192,Golgi apparatus; vesicle-mediated transport,PF11817;PF12742;,1.00E-13,CHOYP_BRAFLDRAFT_87429.1.1,,,,,,,TPC11_HUMAN,Homo sapiens (Human),vesicle-mediated transport [GO:0016192] comp105362_c0_seq1,257,50.1946,0.43539714,1,16,,5.00E-18,Q14667,UPF0378 protein KIAA0100 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein),Protein KIAA0100 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein),GO:0005576,extracellular region,PF10351;PF10344;PF10347;,6.00E-31,CHOYP_LOC100165500.1.1,,,,,,,K0100_HUMAN,Homo sapiens (Human), comp105389_c0_seq1,249,41.7671,0.85228647,6,0,,7.00E-11,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp105389_c1_seq1,225,46.6667,1.0946565,7,3,,3.00E-10,Q8I7P9,Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305; GO:0005634; GO:0008233; GO:0006508; GO:0006313,"DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; peptidase activity; proteolysis; transposition, DNA-mediated",PF00665;PF00078;,,,,,,,,,POL5_DROME,Drosophila melanogaster (Fruit fly),"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp105391_c0_seq1,389,42.6735,1.04077782,0,51,,1.00E-19,Q24799,Myophilin,Myophilin,,,PF00402;PF00307;,,,,,,,,,MYPH_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp105410_c0_seq1,328,49.0854,0.85261563,11,0,,3.00E-08,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp105421_c0_seq1,271,35.0554,0.72728263,7,13,,3.00E-07,Q8N884,Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (Mab-21 domain-containing protein 1),Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1),GO:0005524; GO:0003677; GO:0005525; GO:0002218; GO:0071360; GO:0009190; GO:0061501; GO:0005829; GO:0051607; GO:0045087; GO:0046872; GO:0002230; GO:0032481,ATP binding; DNA binding; GTP binding; activation of innate immune response; cellular response to exogenous dsRNA; cyclic nucleotide biosynthetic process; cyclic-GMP-AMP synthase activity; cytosol; defense response to virus; innate immune response; metal ion binding; positive regulation of defense response to virus by host; positive regulation of type I interferon production,PF03281;,,,,,,,,,M21D1_HUMAN,Homo sapiens (Human),activation of innate immune response [GO:0002218]; cellular response to exogenous dsRNA [GO:0071360]; cyclic nucleotide biosynthetic process [GO:0009190]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481] comp105430_c0_seq1,498,44.1767,0.28877431,25,0,,2.00E-29,Q4G0Z9,MCM domain-containing protein 2,MCM domain-containing protein 2,GO:0005524; GO:0003677; GO:0006260,ATP binding; DNA binding; DNA replication,PF00493;,,,,,,,,,MCMD2_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260] comp105433_c0_seq2,492,44.9187,0.60844418,6,43,,1.00E-10,Q8BTK5,SET and MYND domain-containing protein 4 (EC 2.1.1.-),SET and MYND domain-containing protein 4 (EC 2.1.1.-),GO:0046872; GO:0008168,metal ion binding; methyltransferase activity,PF00856;PF01753;,,,,,,,,,SMYD4_MOUSE,Mus musculus (Mouse), comp105436_c0_seq1,287,42.1603,0.78948327,7,0,,3.00E-32,Q9BWV7,Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2),Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2),GO:0006464; GO:0016874,cellular protein modification process; ligase activity,PF03133;,9.00E-42,CHOYP_BRAFLDRAFT_279373.1.1,,,,,,,TTLL2_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464] comp105436_c1_seq1,296,42.9054,0.44328864,5,8,,5.00E-17,Q80UG8,Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0018095; GO:0015631,cilium; cytoplasm; ligase activity; microtubule basal body; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL4_MOUSE,Mus musculus (Mouse),peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095] comp105445_c0_seq1,1457,34.7975,0.4474562,1311,3800,,3.00E-11,Q8WXF0,"Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)","Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)",GO:0003723; GO:0050733; GO:0000244; GO:0016482; GO:0000395; GO:0048025; GO:0005654; GO:0000166; GO:0000381; GO:0051082,"RNA binding; RS domain binding; assembly of spliceosomal tri-snRNP; cytoplasmic transport; mRNA 5'-splice site recognition; negative regulation of mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding; regulation of alternative mRNA splicing, via spliceosome; unfolded protein binding",PF00076;,2.00E-27,CHOYP_ISCW_ISCW023180.2.2,,,,,,,SRS12_HUMAN,Homo sapiens (Human),"mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp105446_c0_seq2,473,47.1459,0.76267437,16,3,,4.00E-31,P53349,Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),GO:0005524; GO:0008545; GO:0004709; GO:0000186; GO:0008637; GO:0005829; GO:0003382; GO:0061029; GO:0030838; GO:0030334; GO:0007179; GO:0042060; GO:0008270,ATP binding; JUN kinase kinase activity; MAP kinase kinase kinase activity; activation of MAPKK activity; apoptotic mitochondrial changes; cytosol; epithelial cell morphogenesis; eyelid development in camera-type eye; positive regulation of actin filament polymerization; regulation of cell migration; transforming growth factor beta receptor signaling pathway; wound healing; zinc ion binding,PF00069;PF04434;,1.00E-24,CHOYP_LOC100334486.1.1,,,,,,,M3K1_MOUSE,Mus musculus (Mouse),activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060] comp105456_c0_seq1,223,48.8789,0.2271851,8,0,,5.00E-19,Q15413,Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),GO:0005509; GO:0006874; GO:0071318; GO:0071313; GO:0071277; GO:0071286; GO:0016021; GO:0030314; GO:0051289; GO:0005219; GO:0033017; GO:0006941,calcium ion binding; cellular calcium ion homeostasis; cellular response to ATP; cellular response to caffeine; cellular response to calcium ion; cellular response to magnesium ion; integral to membrane; junctional membrane complex; protein homotetramerization; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane; striated muscle contraction,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,1.00E-20,CHOYP_LOC100643070.1.1,,,,,,,RYR3_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; ion transmembrane transport [GO:0034220]; protein homotetramerization [GO:0051289]; regulation of cardiac conduction [GO:1903779] comp105467_c0_seq1,250,46.8,0.66247394,7,22,,1.00E-15,Q8CC12,Codanin-1,Codanin-1,GO:0031497; GO:0005737; GO:0016021; GO:0008156; GO:0005634,chromatin assembly; cytoplasm; integral to membrane; negative regulation of DNA replication; nucleus,PF15296;,2.00E-31,CHOYP_LOC579713.1.1,,,,,,,CDAN1_MOUSE,Mus musculus (Mouse),chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; negative regulation of DNA replication [GO:0008156]; nuclear envelope organization [GO:0006998]; protein localization [GO:0008104] comp105479_c1_seq1,274,59.1241,1.13187483,0,16,,7.00E-43,Q6A8L4,Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transaminase),Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transaminase),GO:0080130; GO:0000105; GO:0004400; GO:0030170,L-phenylalanine:2-oxoglutarate aminotransferase activity; histidine biosynthetic process; histidinol-phosphate transaminase activity; pyridoxal phosphate binding,PF00155;,,,,,,,,,HIS8_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),histidine biosynthetic process [GO:0000105] comp105483_c0_seq1,320,47.5,0.27792479,5,0,,,,,,,,,6.00E-13,CHOYP_LOC100372388.1.1,,,,,,,,, comp105489_c0_seq1,787,42.9479,0.96650002,6,9,,5.00E-44,Q0IID7,Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48),Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48),GO:0005794; GO:0017017; GO:0005737; GO:0046329; GO:0043508; GO:0005634; GO:0035335; GO:0004725,Golgi apparatus; MAP kinase tyrosine/serine/threonine phosphatase activity; cytoplasm; negative regulation of JNK cascade; negative regulation of JUN kinase activity; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00782;PF00581;,1.00E-38,CHOYP_PHUM_PHUM490910.1.1,,,,,,,DUS10_BOVIN,Bos taurus (Bovine),inactivation of MAPK activity [GO:0000188]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496] comp105489_c0_seq2,666,43.3934,1.02369535,0,0,,1.00E-08,O13453,Tyrosine-protein phosphatase pmp1 (EC 3.1.3.48),Tyrosine-protein phosphatase pmp1 (EC 3.1.3.48),GO:0033550; GO:0017017; GO:0007049; GO:0030644; GO:0071472; GO:0005829; GO:0005634; GO:0090028; GO:0022604; GO:0032465,MAP kinase tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; cell cycle; cellular chloride ion homeostasis; cellular response to salt stress; cytosol; nucleus; positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; regulation of cell morphogenesis; regulation of cytokinesis,PF00782;,,,,,,,,,PMP1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [GO:0000754]; cell cycle [GO:0007049]; cellular chloride ion homeostasis [GO:0030644]; cellular response to salt stress [GO:0071472]; MAPK cascade [GO:0000165]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0090028]; protein dephosphorylation [GO:0006470]; regulation of cell morphogenesis [GO:0022604]; regulation of mitotic cytokinesis [GO:1902412]; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0010969] comp105494_c0_seq1,512,45.3125,0.31532967,17,4,,2.00E-25,Q6DFU2,Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog),Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog),GO:0005737; GO:0005856; GO:0005634,cytoplasm; cytoskeleton; nucleus,PF07707;PF00651;PF01344;,2.00E-54,CHOYP_LOC100367192.1.2,,,,,,,NS1BP_XENLA,Xenopus laevis (African clawed frog), comp105494_c1_seq1,562,46.7972,0.5090432,17,32,,3.00E-28,Q96CT2,Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),,,PF07707;PF00651;PF01344;,,,,,,,,,KLH29_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp105500_c0_seq1,243,48.9712,0.62034949,3,12,,2.00E-24,Q96QE2,Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),GO:0016021; GO:0005886; GO:0022891; GO:0055085,integral to membrane; plasma membrane; substrate-specific transmembrane transporter activity; transmembrane transport,PF00083;,6.00E-18,CHOYP_LOC100373277.2.2,,,,,,,MYCT_HUMAN,Homo sapiens (Human),glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428] comp105549_c0_seq1,307,46.2541,0.97837052,4,0,,3.00E-06,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp105583_c0_seq1,233,64.8069,0.82716264,0,12,,1.00E-09,P25777,Oryzain beta chain (EC 3.4.22.-),Oryzain beta chain (EC 3.4.22.-),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF00396;PF08246;PF00112;,,,,,,,,,ORYB_ORYSJ,Oryza sativa subsp. japonica (Rice),proteolysis involved in cellular protein catabolic process [GO:0051603] comp105600_c0_seq1,484,44.8347,0.30017812,6,51,,1.00E-08,P19137,Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),GO:0060445; GO:0007155; GO:0007166; GO:0005911; GO:0060441; GO:0045198; GO:0005201; GO:0043208; GO:0005606; GO:0002011; GO:0031175; GO:0030155; GO:0030334; GO:0045995; GO:0061304,branching involved in salivary gland morphogenesis; cell adhesion; cell surface receptor signaling pathway; cell-cell junction; epithelial tube branching involved in lung morphogenesis; establishment of epithelial cell apical/basal polarity; extracellular matrix structural constituent; glycosphingolipid binding; laminin-1 complex; morphogenesis of an epithelial sheet; neuron projection development; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; retinal blood vessel morphogenesis,PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;,,,,,,,,,LAMA1_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888] comp105628_c0_seq1,252,56.746,1.04341784,0,23,,3.00E-49,Q6A6G6,NADH-quinone oxidoreductase subunit I (EC 1.6.99.5) (NADH dehydrogenase I subunit I) (NDH-1 subunit I),NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I),GO:0051539; GO:0050136; GO:0005506; GO:0005886; GO:0048038,"4 iron, 4 sulfur cluster binding; NADH dehydrogenase (quinone) activity; iron ion binding; plasma membrane; quinone binding",PF12838;,,,,,,,,,NUOI_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp105631_c0_seq1,738,43.6314,0.40539238,3,0,,5.00E-28,Q7Z2W7,Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8),Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8),GO:0005262; GO:0006874; GO:0005789; GO:0009897; GO:0016021; GO:0045121; GO:0051289; GO:0070207; GO:0009409; GO:0050955,calcium channel activity; cellular calcium ion homeostasis; endoplasmic reticulum membrane; external side of plasma membrane; integral to membrane; membrane raft; protein homotetramerization; protein homotrimerization; response to cold; thermoception,PF00520;,,,,,,,,,TRPM8_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; detection of temperature stimulus [GO:0016048]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]; response to cold [GO:0009409]; thermoception [GO:0050955] comp105631_c0_seq2,757,45.5746,0.41401042,7,8,,3.00E-28,Q8R4D5,Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8),Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8),GO:0005262; GO:0006874; GO:0009897; GO:0016021; GO:0045121; GO:0051289; GO:0070207; GO:0009409; GO:0050955,calcium channel activity; cellular calcium ion homeostasis; external side of plasma membrane; integral to membrane; membrane raft; protein homotetramerization; protein homotrimerization; response to cold; thermoception,,2.00E-17,CHOYP_TRPM3.3.7,,,,,,,TRPM8_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; detection of temperature stimulus [GO:0016048]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]; response to cold [GO:0009409]; response to temperature stimulus [GO:0009266]; thermoception [GO:0050955] comp105634_c0_seq1,294,44.5578,0.41804924,3,12,,2.00E-09,P22580,Probable amidase (EC 3.5.1.4),Probable amidase (EC 3.5.1.4),GO:0004040; GO:0016884,"amidase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor",PF01425;,4.00E-15,CHOYP_LOC100712443.1.1,,,,,,,AMDY_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp105634_c1_seq1,448,41.5179,0.36356456,13,11,,4.00E-40,Q90578,Vitamin D3 hydroxylase-associated protein (VDHAP),Vitamin D3 hydroxylase-associated protein (VDHAP),GO:0016884; GO:0016811; GO:0005743,"carbon-nitrogen ligase activity, with glutamine as amido-N-donor; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; mitochondrial inner membrane",PF01425;,,,,,,,,,VDHAP_CHICK,Gallus gallus (Chicken), comp105640_c0_seq1,290,41.0345,0.41762839,14,17,,7.00E-17,Q802D3,Exportin-4,Exportin-4,GO:0005737; GO:0005634; GO:0015031,cytoplasm; nucleus; protein transport,PF08767;,,,,,,,,,XPO4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein export from nucleus [GO:0006611] comp105682_c1_seq2,646,41.9505,0.3534755,4,30,,2.00E-24,Q6PHS9,Voltage-dependent calcium channel subunit alpha-2/delta-2 (Protein ducky) (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2],Voltage-dependent calcium channel subunit alpha-2/delta-2 (Protein ducky) (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2],GO:0046872; GO:0048747; GO:0007528; GO:0046622; GO:0040014; GO:0060024; GO:0005245; GO:0005891,metal ion binding; muscle fiber development; neuromuscular junction development; positive regulation of organ growth; regulation of multicellular organism growth; rhythmic synaptic transmission; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08473;PF00092;PF08399;,,,,,,,,,CA2D2_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; muscle fiber development [GO:0048747]; neuromuscular junction development [GO:0007528]; positive regulation of organ growth [GO:0046622]; regulation of multicellular organism growth [GO:0040014]; rhythmic synaptic transmission [GO:0060024] comp105693_c0_seq1,404,41.5842,0.40459788,3,17,,5.00E-07,P03010,Putative AC9 transposase,Putative AC9 transposase,GO:0003677; GO:0006310; GO:0032196,DNA binding; DNA recombination; transposition,PF05699;PF14372;,,,,,,,,,TRAC9_MAIZE,Zea mays (Maize),DNA recombination [GO:0006310]; transposition [GO:0032196] comp105693_c1_seq1,310,39.6774,0.25271119,4,19,,3.00E-06,O96006,Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog),Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog),GO:0003677; GO:0046872; GO:0000228; GO:0004803,DNA binding; metal ion binding; nuclear chromosome; transposase activity,PF05699;PF02892;,,,,,,,,,ZBED1_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp105694_c0_seq1,296,43.9189,0.84858111,0,35,,5.00E-16,Q03341,Actin-2,Actin-2,GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,,,,,,,,,ACT2_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp105695_c0_seq1,358,42.7374,0.37163851,9,16,,6.00E-46,Q5RCF3,Cullin-2 (CUL-2),Cullin-2 (CUL-2),GO:0031462; GO:0016567; GO:0006511,Cul2-RING ubiquitin ligase complex; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,3.00E-36,CHOYP_CUL2.1.1,,,,,,,CUL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp105705_c0_seq1,602,49.1694,1.02650387,12,27,,3.00E-16,Q9US38,AB hydrolase superfamily protein C1039.03 (EC 3.-.-.-),AB hydrolase superfamily protein C1039.03 (EC 3.-.-.-),GO:0005829; GO:0016787; GO:0005634,cytosol; hydrolase activity; nucleus,PF07859;,4.00E-25,CHOYP_LOC100371983.2.3,,,,,,,YFZ3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),metabolic process [GO:0008152] comp105705_c2_seq1,328,41.4634,0.92576618,8,16,,2.00E-10,P24484,Lipase 2 (EC 3.1.1.3) (Triacylglycerol lipase),Lipase 2 (EC 3.1.1.3) (Triacylglycerol lipase),GO:0016042; GO:0004806,lipid catabolic process; triglyceride lipase activity,PF07859;,,,1.00E-14,ruditapes2_c1318,,,,,LIP2_MORS1,Moraxella sp. (strain TA144),lipid catabolic process [GO:0016042] comp105707_c0_seq1,320,40.625,0.30419629,3,13,,2.00E-07,Q3UE31,Uncharacterized protein KIAA0930 homolog,Uncharacterized protein KIAA0930 homolog,,,PF09741;,1.00E-14,CHOYP_PHUM_PHUM615920.1.1,,,,,,,K0930_MOUSE,Mus musculus (Mouse), comp105751_c0_seq1,204,67.6471,0.95452029,0,0,,2.00E-14,P73651,Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthase)],Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthase)],GO:0005524; GO:0006747; GO:0003919; GO:0009398; GO:0009231; GO:0008531,ATP binding; FAD biosynthetic process; FMN adenylyltransferase activity; FMN biosynthetic process; riboflavin biosynthetic process; riboflavin kinase activity,PF06574;PF01687;,,,,,,,,,RIBF_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231] comp105771_c0_seq1,333,42.6426,0.33366934,5,4,,4.00E-36,F7AEX0,UV-stimulated scaffold protein A,UV-stimulated scaffold protein A,GO:0000993; GO:0005694; GO:0016567; GO:0009411; GO:0006283,RNA polymerase II core binding; chromosome; protein ubiquitination; response to UV; transcription-coupled nucleotide-excision repair,PF09740;,2.00E-12,CHOYP_UVSSA.1.1,,,,,,,UVSSA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283] comp105775_c0_seq1,405,39.0123,0.26363797,7,10,,3.00E-24,Q9JM05,E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma),E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma),GO:0003677; GO:0007259; GO:0016605; GO:0019789; GO:0016055; GO:0005737; GO:0019048; GO:0007275; GO:0032088; GO:0000122; GO:0016363; GO:1902231; GO:1902174; GO:0033235; GO:0016925; GO:0003714; GO:0006351; GO:0008270,"DNA binding; JAK-STAT cascade; PML body; SUMO ligase activity; Wnt receptor signaling pathway; cytoplasm; modulation by virus of host morphology or physiology; multicellular organismal development; negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of keratinocyte apoptotic process; positive regulation of protein sumoylation; protein sumoylation; transcription corepressor activity; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS4_MOUSE,Mus musculus (Mouse),"JAK-STAT cascade [GO:0007259]; multicellular organism development [GO:0007275]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp105779_c0_seq1,906,41.3907,0.82454646,44,83,,3.00E-114,Q96IP4,Protein FAM46A (HBV X-transactivated gene 11 protein) (HBV XAg-transactivated protein 11),Protein FAM46A (HBV X-transactivated gene 11 protein) (HBV XAg-transactivated protein 11),,,PF07984;,6.00E-139,CHOYP_LOC100378790.1.1,,,,,,,FA46A_HUMAN,Homo sapiens (Human),regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468] comp105782_c0_seq1,466,48.7124,0.36456062,13,19,,1.00E-11,P80560,Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.48) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP),Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.48) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP),GO:0005788; GO:0016021; GO:0034260; GO:0035335; GO:0004725; GO:0030141; GO:0043195; GO:0030658,endoplasmic reticulum lumen; integral to membrane; negative regulation of GTPase activity; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; secretory granule; terminal bouton; transport vesicle membrane,PF11548;PF14948;PF00102;,6.00E-28,CHOYP_LOC100865286.1.1,,,,,,,PTPR2_MOUSE,Mus musculus (Mouse),insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; negative regulation of GTPase activity [GO:0034260]; neurotransmitter secretion [GO:0007269] comp105789_c0_seq1,252,37.6984,0.93445608,0,42,,3.00E-07,Q96NG8,Zinc finger protein 582,Zinc finger protein 582,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN582_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp105799_c0_seq1,742,36.3881,0.49807364,27,58,,2.00E-12,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp105804_c0_seq1,306,34.9673,0.53671902,20,48,,,,,,,,,9.00E-11,CHOYP_contig_002852,,,,,,,,, comp105812_c1_seq1,532,37.0301,0.49596949,21,37,,5.00E-16,Q2HZX7,Protein fuzzy homolog (Xfy),Protein fuzzy homolog (Xfy),GO:0042384; GO:0005737; GO:0005856; GO:0010172; GO:0048704; GO:0001736; GO:0001843; GO:0015031; GO:0008589,cilium assembly; cytoplasm; cytoskeleton; embryonic body morphogenesis; embryonic skeletal system morphogenesis; establishment of planar polarity; neural tube closure; protein transport; regulation of smoothened signaling pathway,,,,5.00E-15,ruditapes_c16576,,,,,FUZZY_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium assembly [GO:0042384]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589] comp105824_c0_seq1,436,43.3486,0.30666828,6,36,,3.00E-60,Q5ZHV7,SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein homolog) (CLL deletion region gene 6 protein homolog),SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein homolog) (CLL deletion region gene 6 protein homolog),,,PF00622;,1.00E-36,CHOYP_LOC100377663.1.1,,,,,,,SPRY7_CHICK,Gallus gallus (Chicken), comp105827_c1_seq1,371,39.6226,0.70911686,12,19,,,,,,,,,7.00E-13,CHOYP_BRAFLDRAFT_126480.1.1,,,,,,,,, comp105829_c0_seq1,756,47.3545,0.64032067,33,4,,2.00E-53,Q9QYP0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity,PF00431;PF12947;PF07645;PF00053;PF01437;,,,,,,,,,MEGF8_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp105830_c0_seq1,561,36.1854,0.65654414,9,54,,1.00E-09,A9JRD8,BTB/POZ domain-containing protein 6-A,BTB/POZ domain-containing protein 6-A,GO:0030154; GO:0000932; GO:0007399,cell differentiation; cytoplasmic mRNA processing body; nervous system development,PF07707;PF00651;PF08005;,,,,,,,,,BTB6A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of neurogenesis [GO:0050767] comp105834_c0_seq1,285,46.3158,0.39430633,9,18,,3.00E-44,Q8IYD8,Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0071821; GO:0043240; GO:0003682; GO:0004518; GO:0090305; GO:0031297; GO:0000712,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; FANCM-MHF complex; Fanconi anaemia nuclear complex; chromatin binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; replication fork processing; resolution of meiotic recombination intermediates,PF02732;PF16783;PF00271;PF04851;,2.00E-36,CHOYP_BRAFLDRAFT_118736.1.1,,,,,,,FANCM_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp105856_c0_seq1,644,39.2857,0.89414204,18,54,,2.00E-27,O75897,Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),GO:0050427; GO:0005829; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1C4_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923] comp105861_c0_seq1,331,35.0453,0.39583074,5,26,,1.00E-10,Q9UKJ5,Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia),Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia),GO:0005798; GO:0005886,Golgi-associated vesicle; plasma membrane,PF10256;,4.00E-15,CHOYP_LOC100366987.2.2,,,,,,,CHIC2_HUMAN,Homo sapiens (Human),Golgi to plasma membrane transport [GO:0006893] comp105871_c1_seq1,444,43.6937,0.52833511,5,15,,2.00E-09,Q08DJ5,Cadherin-18,Cadherin-18,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;,,,,,,,,,CAD18_BOVIN,Bos taurus (Bovine),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp105871_c2_seq1,273,42.1245,0.24909425,0,20,,1.00E-10,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp105872_c0_seq2,906,42.4945,0.28443985,10,14,,1.00E-59,A6NEE1,Pleckstrin homology domain-containing family D member 1 (PH domain-containing family D member 1),Pleckstrin homology domain-containing family D member 1 (PH domain-containing family D member 1),GO:0005543,phospholipid binding,PF00169;,4.00E-27,CHOYP_PLHD1.1.1,,,,,,,PLHD1_HUMAN,Homo sapiens (Human), comp105873_c0_seq1,531,47.081,0.58063894,13,9,,2.00E-28,Q25514,Protein hunchback (Fragment),Protein hunchback (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0040034; GO:0035282; GO:0000981; GO:0006366,"DNA binding; metal ion binding; nucleus; regulation of development, heterochronic; segmentation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter",,7.00E-53,CHOYP_HB.1.1,,,,,,,HUNB_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),"regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]" comp105894_c1_seq1,423,49.6454,0.7697937,12,21,,8.00E-36,Q9NZN5,Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF),Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF),GO:0001664; GO:0007186; GO:0005096; GO:0005089; GO:0097190; GO:0007411; GO:0005829; GO:0016020; GO:0048011; GO:0005543; GO:0043547; GO:0043065; GO:0035023; GO:0051056; GO:0007264; GO:0038032,G-protein coupled receptor binding; G-protein coupled receptor signaling pathway; GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; axon guidance; cytosol; membrane; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of GTPase activity; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; termination of G-protein coupled receptor signaling pathway,PF00595;PF09128;PF00621;,8.00E-32,CHOYP_LOC100644321.4.7,,,,,,,ARHGC_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp105903_c0_seq1,398,40.4523,1.14423799,10,61,,,,,,,,,2.00E-20,CHOYP_LOC100374651.4.4,,,,,,,,, comp105903_c3_seq1,848,39.033,0.98242018,26,150,,2.00E-27,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp105905_c0_seq1,340,46.7647,0.10982382,19,0,,2.00E-18,Q9VT28,Protein furry,Protein furry,GO:0048800; GO:0045177; GO:0005938; GO:0008407; GO:0070593; GO:0035317; GO:0048601; GO:0045860; GO:0045893; GO:0048814; GO:0042052; GO:0006351,"antennal morphogenesis; apical part of cell; cell cortex; chaeta morphogenesis; dendrite self-avoidance; imaginal disc-derived wing hair organization; oocyte morphogenesis; positive regulation of protein kinase activity; positive regulation of transcription, DNA-dependent; regulation of dendrite morphogenesis; rhabdomere development; transcription, DNA-dependent",PF14225;PF14228;PF14222;,,,,,,,,,FRY_DROME,Drosophila melanogaster (Fruit fly),"actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]" comp105912_c0_seq1,480,44.5833,0.71930291,12,39,,4.00E-20,Q64512,Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),GO:0005737; GO:0005856; GO:0030027; GO:0005634; GO:0004725,cytoplasm; cytoskeleton; lamellipodium; nucleus; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,,,,,,,,,PTN13_MOUSE,Mus musculus (Mouse),peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp105918_c1_seq1,1008,41.9643,0.52707297,31,10,,7.00E-24,P14314,Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH),Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH),GO:0006491; GO:0003723; GO:0005509; GO:0005788; GO:0001701; GO:0045087; GO:0007243; GO:0001889; GO:0010977; GO:0006807; GO:0043687; GO:0018279; GO:0006457; GO:0051291; GO:0072001,N-glycan processing; RNA binding; calcium ion binding; endoplasmic reticulum lumen; in utero embryonic development; innate immune response; intracellular protein kinase cascade; liver development; negative regulation of neuron projection development; nitrogen compound metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding; protein heterooligomerization; renal system development,PF13202;PF12999;PF13015;,,,,,,,,,GLU2B_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; N-glycan processing [GO:0006491]; protein folding [GO:0006457] comp105919_c0_seq1,362,38.9503,0.51250895,19,0,,5.00E-12,Q8BXR5,Sodium leak channel non-selective protein (Voltage gated channel-like protein 1),Sodium leak channel non-selective protein (Voltage gated channel-like protein 1),GO:0016021; GO:0005272; GO:0035725; GO:0005244,integral to membrane; sodium channel activity; sodium ion transmembrane transport; voltage-gated ion channel activity,PF00520;,6.00E-20,CHOYP_ISCW_ISCW004615.1.1,,,,,,,NALCN_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010] comp105922_c0_seq1,267,43.8202,1.09837606,0,45,,8.00E-10,Q5TZ24,DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-),DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp105922_c1_seq1,441,46.0317,1.16180504,0,65,,2.00E-19,Q7Z0T3,Temptin,Temptin,GO:0005576,extracellular region,,2.00E-15,CHOYP_ACDOPBH.9.9,,,,,,,TEMPT_APLCA,Aplysia californica (California sea hare), comp105928_c0_seq1,843,45.5516,0.3716532,4,189,,,,,,,,,2.00E-24,CHOYP_BRAFLDRAFT_66688.2.2,,,,,,,,, comp105928_c1_seq1,731,42.9549,0.38607667,8,157,,1.00E-06,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp105956_c1_seq1,808,44.0594,0.81161937,27,46,,2.00E-124,Q91880,Suppressor of hairless protein homolog (X-Su(H)),Suppressor of hairless protein homolog (X-Su(H)),GO:0000978; GO:0000982; GO:0005737; GO:0007275; GO:0005634; GO:0007221,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; cytoplasm; multicellular organismal development; nucleus; positive regulation of transcription of Notch receptor target,PF09270;PF09271;PF01833;,7.00E-106,CHOYP_SUH.1.1,,,,,,,SUH_XENLA,Xenopus laevis (African clawed frog),"multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; transcription, DNA-templated [GO:0006351]" comp105966_c0_seq1,530,47.5472,1.35226814,8,97,,3.00E-09,Q9V5N8,Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),GO:0004930; GO:0007464; GO:0048057; GO:0016055; GO:0007411; GO:0005509; GO:0016339; GO:0050839; GO:0005911; GO:0048813; GO:0070593; GO:0007156; GO:0005887; GO:0016319; GO:0030178; GO:0007218; GO:0016318; GO:0030177; GO:0005057; GO:0050770; GO:0090175; GO:0051963; GO:0035159; GO:0007367; GO:0004888,"G-protein coupled receptor activity; R3/R4 cell fate commitment; R3/R4 development; Wnt receptor signaling pathway; axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell junction; dendrite morphogenesis; dendrite self-avoidance; homophilic cell adhesion; integral to plasma membrane; mushroom body development; negative regulation of Wnt receptor signaling pathway; neuropeptide signaling pathway; ommatidial rotation; positive regulation of Wnt receptor signaling pathway; receptor signaling protein activity; regulation of axonogenesis; regulation of establishment of planar polarity; regulation of synapse assembly; regulation of tube length, open tracheal system; segment polarity determination; transmembrane signaling receptor activity",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,STAN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]" comp105969_c0_seq1,276,38.7681,0.69102832,5,3,,4.00E-11,Q1JPT7,THAP domain-containing protein 1,THAP domain-containing protein 1,GO:0007049; GO:0046872; GO:0005654; GO:0006355; GO:0043565; GO:0006351,"cell cycle; metal ion binding; nucleoplasm; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF05485;,,,,,,,,,THAP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp105969_c0_seq2,297,36.0269,0.84961761,0,15,,2.00E-07,Q6P3Z3,THAP domain-containing protein 4,THAP domain-containing protein 4,GO:0003677; GO:0046872,DNA binding; metal ion binding,PF08768;PF05485;,,,,,,,,,THAP4_MOUSE,Mus musculus (Mouse), comp1059_c0_seq1,229,55.8952,1.18181847,0,1,,5.00E-45,Q6A7L9,Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS),Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS),GO:0005524; GO:0002161; GO:0005737; GO:0004827; GO:0006433; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; proline-tRNA ligase activity; prolyl-tRNA aminoacylation; regulation of translational fidelity,PF03129;PF00587;PF04073;,,,,,,,,,SYP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),prolyl-tRNA aminoacylation [GO:0006433] comp106002_c0_seq1,562,55.516,0.7403352,20,32,,9.00E-16,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp106014_c0_seq1,315,39.6825,0.33492653,13,0,,3.00E-38,P70704,Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II),Phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1),GO:0005524; GO:0019829; GO:0042584; GO:0005783; GO:0016021; GO:0000287; GO:0004012; GO:0005886,ATP binding; cation-transporting ATPase activity; chromaffin granule membrane; endoplasmic reticulum; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity; plasma membrane,PF00122;PF16212;PF16209;,8.00E-43,CHOYP_AT8A1.2.2,,,,,,,AT8A1_MOUSE,Mus musculus (Mouse),Golgi vesicle budding [GO:0048194]; learning [GO:0007612]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092] comp106014_c1_seq1,354,44.6328,0.5126806,19,6,,2.00E-19,P39524,Probable phospholipid-transporting ATPase DRS2 (EC 3.6.3.1),Probable phospholipid-transporting ATPase DRS2 (EC 3.6.3.1),GO:0005524; GO:0005794; GO:0019829; GO:0006897; GO:0016021; GO:0006886; GO:0000287; GO:0045332; GO:0004012; GO:0006892; GO:0000028; GO:0005802,ATP binding; Golgi apparatus; cation-transporting ATPase activity; endocytosis; integral to membrane; intracellular protein transport; magnesium ion binding; phospholipid translocation; phospholipid-translocating ATPase activity; post-Golgi vesicle-mediated transport; ribosomal small subunit assembly; trans-Golgi network,PF00122;PF16212;PF16209;,,,,,,,,,ATC3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; Golgi vesicle budding [GO:0048194]; intracellular protein transport [GO:0006886]; phospholipid translocation [GO:0045332]; post-Golgi vesicle-mediated transport [GO:0006892]; response to pheromone involved in conjugation with cellular fusion [GO:0000749]; ribosomal small subunit assembly [GO:0000028] comp106021_c1_seq2,470,44.4681,0.60618035,0,42,,4.00E-12,P23654,Neurotactin,Neurotactin,GO:0007411; GO:0007413; GO:0016323; GO:0004091; GO:0007155; GO:0007417; GO:0016021,axon guidance; axonal fasciculation; basolateral plasma membrane; carboxylesterase activity; cell adhesion; central nervous system development; integral to membrane,PF00135;,,,,,,,,,NRT_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp106038_c0_seq1,677,42.9838,0.5839806,26,46,,3.00E-39,Q8N584,Tetratricopeptide repeat protein 39C (TPR repeat protein 39C),Tetratricopeptide repeat protein 39C (TPR repeat protein 39C),,,PF10300;,1.00E-57,CHOYP_TT39C.1.1,,,,,,,TT39C_HUMAN,Homo sapiens (Human), comp106038_c1_seq1,343,43.1487,0.58960699,4,1,,9.00E-10,Q28D40,Tetratricopeptide repeat protein 39A (TPR repeat protein 39A),Tetratricopeptide repeat protein 39A (TPR repeat protein 39A),,,PF10300;PF13174;,,,,,,,,,TT39A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp106038_c3_seq1,347,42.3631,1.05216293,13,12,,2.00E-11,Q5XHH9,Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),,,PF10300;PF13181;,,,,,,,,,TT39B_XENLA,Xenopus laevis (African clawed frog), comp106039_c0_seq1,657,42.9224,0.3008389,19,40,,1.00E-08,Q9UKK3,Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),GO:0003677; GO:0006281; GO:0003950; GO:0008219; GO:0005737; GO:0019899; GO:0006954; GO:0005634; GO:0006471; GO:0042493; GO:0030529; GO:0005876; GO:0006810,DNA binding; DNA repair; NAD+ ADP-ribosyltransferase activity; cell death; cytoplasm; enzyme binding; inflammatory response; nucleus; protein ADP-ribosylation; response to drug; ribonucleoprotein complex; spindle microtubule; transport,PF00533;PF00644;PF08487;PF00092;,,,,,,,,,PARP4_HUMAN,Homo sapiens (Human),cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810] comp106044_c1_seq1,503,42.3459,0.48966807,6,0,,3.00E-38,Q7Z403,Transmembrane channel-like protein 6 (Epidermodysplasia verruciformis protein 1) (Protein LAK-4),Transmembrane channel-like protein 6 (Epidermodysplasia verruciformis protein 1) (Protein LAK-4),GO:0005789; GO:0016021; GO:0006811,endoplasmic reticulum membrane; integral to membrane; ion transport,PF07810;,,,,,,,,,TMC6_HUMAN,Homo sapiens (Human),ion transport [GO:0006811] comp106044_c1_seq2,488,42.0082,0.5119953,2,0,,3.00E-34,Q6UXY8,Transmembrane channel-like protein 5,Transmembrane channel-like protein 5,GO:0016021; GO:0006811,integral to membrane; ion transport,PF07810;,3.00E-19,CHOYP_LOC578478.1.1,,,,,,,TMC5_HUMAN,Homo sapiens (Human),ion transport [GO:0006811] comp106045_c0_seq2,282,43.9716,0.37159081,4,17,,2.00E-18,Q9NTJ4,Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1),Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1),GO:0004559; GO:0030246; GO:0006013; GO:0008270,alpha-mannosidase activity; carbohydrate binding; mannose metabolic process; zinc ion binding,PF09261;PF01074;PF07748;,5.00E-13,CHOYP_MA2C1.1.1,,,,,,,MA2C1_HUMAN,Homo sapiens (Human),mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517] comp106074_c1_seq1,528,47.5379,1.04319713,15,64,,1.00E-53,Q9WU22,Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Testis-enriched protein tyrosine phosphatase),Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Testis-enriched protein tyrosine phosphatase),GO:0005737; GO:0005856; GO:0004726; GO:0005886,cytoplasm; cytoskeleton; non-membrane spanning protein tyrosine phosphatase activity; plasma membrane,PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;,8.00E-46,CHOYP_PTN4.2.2,,,,,,,PTN4_MOUSE,Mus musculus (Mouse), comp106085_c0_seq1,404,40.3465,0.62212363,11,3,,4.00E-33,Q78S06,Protein SYS1 homolog,Protein SYS1 homolog,GO:0000139; GO:0016021; GO:0015031,Golgi membrane; integral to membrane; protein transport,PF09801;,2.00E-20,CHOYP_LOC100710299.1.1,,,,,,,SYS1_MOUSE,Mus musculus (Mouse),Golgi to endosome transport [GO:0006895]; Golgi to plasma membrane protein transport [GO:0043001]; protein targeting to Golgi [GO:0000042] comp106100_c1_seq1,317,42.2713,0.49599424,8,1,,3.00E-40,Q9HAC7,Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13),Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase),GO:0005739; GO:0047369,mitochondrion; succinate-hydroxymethylglutarate CoA-transferase activity,PF02515;,,,,,,,,,CG010_HUMAN,Homo sapiens (Human), comp106121_c0_seq1,662,46.2236,0.66162074,19,37,,1.00E-36,Q8TEB9,Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4),Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4),GO:0030433; GO:0006915; GO:0034644; GO:0034620; GO:0044322; GO:0030176; GO:0031293; GO:0033619; GO:0005739; GO:0043066; GO:0045732; GO:0010954; GO:0051047; GO:0043687; GO:0004252; GO:0048515,ER-associated protein catabolic process; apoptotic process; cellular response to UV; cellular response to unfolded protein; endoplasmic reticulum quality control compartment; integral to endoplasmic reticulum membrane; membrane protein intracellular domain proteolysis; membrane protein proteolysis; mitochondrion; negative regulation of apoptotic process; positive regulation of protein catabolic process; positive regulation of protein processing; positive regulation of secretion; post-translational protein modification; serine-type endopeptidase activity; spermatid differentiation,PF01694;,1.00E-12,CHOYP_LOC100376736.1.1,,,,,,,RHBL4_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515]" comp106131_c0_seq1,442,49.3213,0.63408593,16,21,,1.00E-46,Q8IWF2,FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),GO:0030433; GO:0005788; GO:0050660; GO:0016491,ER-associated protein catabolic process; endoplasmic reticulum lumen; flavin adenine dinucleotide binding; oxidoreductase activity,,,,,,,,,,FXRD2_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114] comp106134_c0_seq1,433,36.9515,0.6220769,31,144,,9.00E-10,E9QJ05,"Protein PET117 homolog, mitochondrial","Protein PET117 homolog, mitochondrial",GO:0005739,mitochondrion,PF15786;,,,,,,,,,PT117_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp106135_c0_seq1,649,38.829,0.4145418,28,20,,4.00E-19,Q5XHH9,Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),,,PF10300;PF13181;,,,,,,,,,TT39B_XENLA,Xenopus laevis (African clawed frog), comp106135_c1_seq1,340,41.4706,0.68889485,15,0,,1.00E-18,D3ZC96,Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),,,PF10300;,5.00E-40,CHOYP_BRAFLDRAFT_205333.1.1,,,,,,,TT39B_RAT,Rattus norvegicus (Rat), comp106139_c0_seq1,655,38.7786,0.29270848,16,36,,2.00E-57,Q9UIC8,Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1),Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1),GO:0008757; GO:0031333; GO:0003880; GO:0042981; GO:0090266,S-adenosylmethionine-dependent methyltransferase activity; negative regulation of protein complex assembly; protein C-terminal carboxyl O-methyltransferase activity; regulation of apoptotic process; regulation of mitotic cell cycle spindle assembly checkpoint,PF04072;,,,,,,,,,LCMT1_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] comp106150_c0_seq1,548,42.1533,0.12469757,15,23,,3.00E-09,Q0P4A7,Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein),Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein),,,,,,,,,,,,SNP47_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] comp106150_c1_seq1,460,39.7826,0.41789889,8,17,,2.00E-13,Q6P6S0,Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein),Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein),GO:0031083; GO:0012505; GO:0016020; GO:0048471,BLOC-1 complex; endomembrane system; membrane; perinuclear region of cytoplasm,,,,,,,,,,SNP47_RAT,Rattus norvegicus (Rat),long-term synaptic potentiation [GO:0060291]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] comp106156_c0_seq3,1390,38.1295,0.44396431,41,69,,7.00E-86,Q91YE3,Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20),Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20),GO:0031418; GO:0055008; GO:0005737; GO:0060347; GO:0005506; GO:0060711; GO:0043433; GO:0005634; GO:0032364; GO:0031545; GO:0018401; GO:0045765; GO:0001666; GO:0071731; GO:0060412,L-ascorbic acid binding; cardiac muscle tissue morphogenesis; cytoplasm; heart trabecula formation; iron ion binding; labyrinthine layer development; negative regulation of sequence-specific DNA binding transcription factor activity; nucleus; oxygen homeostasis; peptidyl-proline 4-dioxygenase activity; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; regulation of angiogenesis; response to hypoxia; response to nitric oxide; ventricular septum morphogenesis,PF13640;PF01753;,2.00E-19,CHOYP_EGLN1.1.1,,,,,,,EGLN1_MOUSE,Mus musculus (Mouse),cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of neuron death [GO:1901214]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412] comp106157_c0_seq1,557,40.2154,0.81000261,17,76,,1.00E-09,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp106171_c0_seq1,501,45.1098,0.29058249,11,24,,5.00E-34,Q6PCN7,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (P113) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (P113) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein),GO:0005524; GO:0016887; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005730; GO:0005654; GO:0016567; GO:0006357; GO:0006351; GO:0008270,"ATP binding; ATPase activity; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleolus; nucleoplasm; protein ubiquitination; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,1.00E-36,CHOYP_HLTF.1.1,,,,,,,HLTF_MOUSE,Mus musculus (Mouse),chromatin modification [GO:0016568]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp106190_c0_seq1,856,41.9393,0.58571065,40,51,,3.00E-48,Q2VPU4,MLX-interacting protein (Transcriptional activator MondoA),MLX-interacting protein (Transcriptional activator MondoA),GO:0003677; GO:0005737; GO:0005741; GO:0006913; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; mitochondrial outer membrane; nucleocytoplasmic transport; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00010;,2.00E-31,CHOYP_MLXIP.2.3,,,,,,,MLXIP_MOUSE,Mus musculus (Mouse),"nucleocytoplasmic transport [GO:0006913]; regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter [GO:1900402]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp106193_c0_seq1,368,50.5435,0.38437784,4,0,,1.00E-44,Q61493,DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0005694; GO:0046872; GO:0000166; GO:0005634; GO:0019985; GO:0016035,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; chromosome; metal ion binding; nucleotide binding; nucleus; translesion synthesis; zeta DNA polymerase complex",PF00136;PF03104;PF15735;PF14260;,2.00E-46,CHOYP_REV3L.1.1,,,,,,,DPOLZ_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276] comp106202_c2_seq1,470,45.7447,0.99894408,6,15,,2.00E-14,Q9WV18,Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1),Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1),GO:0004965; GO:0038039; GO:0007193; GO:0030054; GO:0005737; GO:0030425; GO:0007214; GO:0005887; GO:0045211; GO:0042734,G-protein coupled GABA receptor activity; G-protein coupled receptor heterodimeric complex; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; cell junction; cytoplasm; dendrite; gamma-aminobutyric acid signaling pathway; integral to plasma membrane; postsynaptic membrane; presynaptic membrane,PF00003;PF01094;PF00084;,,,,,,,,,GABR1_MOUSE,Mus musculus (Mouse),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094] comp10620_c0_seq1,277,43.6823,0.31972815,8,0,,1.00E-19,Q9Y2G3,Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B),Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B),GO:0005524; GO:0015917; GO:0019829; GO:0005769; GO:0005783; GO:0016021; GO:0015075; GO:0000287; GO:0005637; GO:0045332; GO:0004012; GO:0005886; GO:0055037; GO:0055038,ATP binding; aminophospholipid transport; cation-transporting ATPase activity; early endosome; endoplasmic reticulum; integral to membrane; ion transmembrane transporter activity; magnesium ion binding; nuclear inner membrane; phospholipid translocation; phospholipid-translocating ATPase activity; plasma membrane; recycling endosome; recycling endosome membrane,PF00122;PF16212;PF16209;,,,,,,,,,AT11B_HUMAN,Homo sapiens (Human),aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332] comp106210_c1_seq1,261,61.6858,1.18019751,0,13,,4.00E-17,Q6AA89,4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2),4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.7.4),GO:0051538; GO:0051745; GO:0050992; GO:0019288; GO:0046872; GO:0016114,"3 iron, 4 sulfur cluster binding; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; dimethylallyl diphosphate biosynthetic process; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; metal ion binding; terpenoid biosynthetic process",PF02401;,,,,,,,,,ISPH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]" comp106225_c0_seq1,550,48.1818,0.78463463,26,0,,2.00E-07,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp106227_c0_seq2,928,41.8103,0.69588096,23,30,,1.00E-17,Q8C4S8,DENN domain-containing protein 2A,DENN domain-containing protein 2A,GO:0017112; GO:0015629; GO:0005737; GO:0015031; GO:0042147,"Rab guanyl-nucleotide exchange factor activity; actin cytoskeleton; cytoplasm; protein transport; retrograde transport, endosome to Golgi",PF03455;PF02141;PF03456;,,,,,,,,,DEN2A_MOUSE,Mus musculus (Mouse),"protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp106245_c0_seq1,892,44.2825,0.50764922,14,16,,3.00E-83,Q9W5D0,Uncharacterized protein CG42248,Uncharacterized protein CG43867,GO:0005856; GO:0005543,cytoskeleton; phospholipid binding,PF00373;PF00784;PF00169;,2.00E-69,CHOYP_PKHH2.1.1,,,,,,,Y34F_DROME,Drosophila melanogaster (Fruit fly), comp106251_c0_seq1,513,51.6569,0.82836737,0,42,,7.00E-07,A8T6A6,Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9),Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9),GO:0005794; GO:0034185; GO:0006915; GO:0009986; GO:0008203; GO:0005769; GO:0005783; GO:0005576; GO:0005770; GO:0030169; GO:0032802; GO:0005764; GO:0043086; GO:0043621; GO:0006508; GO:0043523; GO:0004252; GO:0034189,Golgi apparatus; apolipoprotein binding; apoptotic process; cell surface; cholesterol metabolic process; early endosome; endoplasmic reticulum; extracellular region; late endosome; low-density lipoprotein particle binding; low-density lipoprotein particle receptor catabolic process; lysosome; negative regulation of catalytic activity; protein self-association; proteolysis; regulation of neuron apoptotic process; serine-type endopeptidase activity; very-low-density lipoprotein particle binding,PF05922;PF00082;,,,,,,,,,PCSK9_LAGLA,Lagothrix lagotricha (Brown woolly monkey) (Humboldt's woolly monkey),apoptotic process [GO:0006915]; cholesterol metabolic process [GO:0008203]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; regulation of neuron apoptotic process [GO:0043523] comp106253_c0_seq1,504,42.2619,0.75732479,20,16,,4.00E-44,Q61263,Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1),Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1),GO:0034736; GO:0015485; GO:0033344; GO:0034435; GO:0008203; GO:0010878; GO:0005789; GO:0000062; GO:0016021; GO:0010742; GO:0042986; GO:0004772; GO:0034379,cholesterol O-acyltransferase activity; cholesterol binding; cholesterol efflux; cholesterol esterification; cholesterol metabolic process; cholesterol storage; endoplasmic reticulum membrane; fatty-acyl-CoA binding; integral to membrane; macrophage derived foam cell differentiation; positive regulation of amyloid precursor protein biosynthetic process; sterol O-acyltransferase activity; very-low-density lipoprotein particle assembly,PF03062;,2.00E-28,CHOYP_LOC100716750.1.1,,,,,,,SOAT1_MOUSE,Mus musculus (Mouse),cholesterol efflux [GO:0033344]; cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol storage [GO:0010878]; macrophage derived foam cell differentiation [GO:0010742]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; very-low-density lipoprotein particle assembly [GO:0034379] comp106263_c0_seq1,612,42.4837,0.72526503,0,0,,,,,,,,,5.00E-37,CHOYP_GRDN.4.5,,,,,,,,, comp106263_c0_seq2,868,42.7419,0.61777333,4,24,,9.00E-42,Q3V6T2,Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),GO:0006260; GO:0005794; GO:0031929; GO:0003779; GO:0032148; GO:0016477; GO:0016023; GO:0031410; GO:0005829; GO:0005783; GO:0030027; GO:0030032; GO:0061024; GO:0008017; GO:0035091; GO:0005886; GO:0006275; GO:0032956; GO:0042127; GO:0010975,DNA replication; Golgi apparatus; TOR signaling cascade; actin binding; activation of protein kinase B activity; cell migration; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; endoplasmic reticulum; lamellipodium; lamellipodium assembly; membrane organization; microtubule binding; phosphatidylinositol binding; plasma membrane; regulation of DNA replication; regulation of actin cytoskeleton organization; regulation of cell proliferation; regulation of neuron projection development,PF05622;,,,,,,,,,GRDN_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp106267_c0_seq1,235,49.3617,0.56544899,8,11,,,,,,,,,2.00E-17,CHOYP_VKR.1.1,,,,,,,,, comp106267_c1_seq2,377,48.2759,0.73070467,0,8,,3.00E-11,Q9Z0U4,Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1),Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1),GO:0004965; GO:0038039; GO:0007193; GO:0030673; GO:0030054; GO:0043198; GO:0043197; GO:0005789; GO:0005615; GO:0007214; GO:0005887; GO:0045121; GO:0031966; GO:0007194; GO:0008285; GO:0033602; GO:0032811; GO:0014053; GO:0050805; GO:0043025; GO:0001649; GO:0014049; GO:0060124; GO:0045211; GO:0045471; GO:0035094; GO:0008021,G-protein coupled GABA receptor activity; G-protein coupled receptor heterodimeric complex; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; axolemma; cell junction; dendritic shaft; dendritic spine; endoplasmic reticulum membrane; extracellular space; gamma-aminobutyric acid signaling pathway; integral to plasma membrane; membrane raft; mitochondrial membrane; negative regulation of adenylate cyclase activity; negative regulation of cell proliferation; negative regulation of dopamine secretion; negative regulation of epinephrine secretion; negative regulation of gamma-aminobutyric acid secretion; negative regulation of synaptic transmission; neuronal cell body; osteoblast differentiation; positive regulation of glutamate secretion; positive regulation of growth hormone secretion; postsynaptic membrane; response to ethanol; response to nicotine; synaptic vesicle,PF00003;PF01094;PF00084;,,,,,,,,,GABR1_RAT,Rattus norvegicus (Rat),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of cAMP biosynthetic process [GO:0030817]; regulation of glutamate secretion [GO:0014048]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094] comp106286_c0_seq1,869,44.7641,0.41474709,27,21,,2.00E-82,Q5RC19,Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),GO:0003995; GO:0003997; GO:0033540; GO:0019395; GO:0050660; GO:0006091; GO:0005777; GO:0006693,acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid oxidation; flavin adenine dinucleotide binding; generation of precursor metabolites and energy; peroxisome; prostaglandin metabolic process,PF01756;PF02770;PF14749;,1.00E-40,CHOYP_ACOX1.2.3,,,,,,,ACOX1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693] comp106312_c0_seq2,481,42.2037,0.48579126,2,3,,5.00E-21,Q90YK5,Heparanase (EC 3.2.1.166),Heparanase (EC 3.2.1.166),GO:0007160; GO:0005576; GO:0030200; GO:0030305; GO:0016020,cell-matrix adhesion; extracellular region; heparan sulfate proteoglycan catabolic process; heparanase activity; membrane,PF03662;,,,,,,,,,HPSE_CHICK,Gallus gallus (Chicken),angiogenesis involved in wound healing [GO:0060055]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heparan sulfate proteoglycan catabolic process [GO:0030200] comp106318_c0_seq1,1333,44.9362,0.31755442,80,56,,4.00E-178,Q9NU22,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0016887; GO:0005730; GO:0005634; GO:0006461; GO:0051082,ATP binding; ATPase activity; nucleolus; nucleus; protein complex assembly; unfolded protein binding,PF07728;,2.00E-115,CHOYP_MDN1.1.8,,,,,,,MDN1_HUMAN,Homo sapiens (Human),protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027] comp106322_c1_seq2,611,43.0442,0.53428149,7,41,,2.00E-11,Q3U827,E3 ubiquitin-protein ligase RNF180 (EC 6.3.2.-) (RING finger protein 180),E3 ubiquitin-protein ligase RNF180 (EC 6.3.2.-) (RING finger protein 180),GO:0016021; GO:0031227; GO:0005635; GO:0032436; GO:0031624; GO:0004842; GO:0008270,integral to membrane; intrinsic to endoplasmic reticulum membrane; nuclear envelope; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin conjugating enzyme binding; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN180_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; norepinephrine metabolic process [GO:0042415]; organic cyclic compound metabolic process [GO:1901360]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein polyubiquitination [GO:0000209]; regulation of catalytic activity [GO:0050790]; serotonin metabolic process [GO:0042428] comp106326_c0_seq1,374,63.6364,1.16724094,1,28,,7.00E-75,Q6A8I8,Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),GO:0005524; GO:0004813; GO:0006419; GO:0005737; GO:0000049; GO:0008270,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytoplasm; tRNA binding; zinc ion binding,PF02272;PF01411;PF07973;,,,,,,,,,SYA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),alanyl-tRNA aminoacylation [GO:0006419] comp106329_c1_seq1,695,43.1655,0.50793756,40,6,,,,,,,,,9.00E-15,CHOYP_BRAFLDRAFT_126447.3.3,,,,,,,,, comp106336_c0_seq1,643,42.7683,0.34193563,15,10,,7.00E-25,Q8CHG3,GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185),GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185),GO:0005794; GO:0090161; GO:0034499; GO:0016020; GO:0034453; GO:0031023; GO:0034067; GO:0000042; GO:0006622; GO:0071955; GO:0070861; GO:0005802,Golgi apparatus; Golgi ribbon formation; late endosome to Golgi transport; membrane; microtubule anchoring; microtubule organizing center organization; protein localization to Golgi apparatus; protein targeting to Golgi; protein targeting to lysosome; recycling endosome to Golgi transport; regulation of protein exit from endoplasmic reticulum; trans-Golgi network,PF01465;PF16704;,,,,,,,,,GCC2_MOUSE,Mus musculus (Mouse),"Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]" comp106336_c0_seq2,452,42.4779,0.50221975,0,0,,2.00E-15,Q7Z3J3,RanBP2-like and GRIP domain-containing protein 4,RanBP2-like and GRIP domain-containing protein 4,GO:0000042,protein targeting to Golgi,PF01465;PF16704;PF00638;,2.00E-14,CHOYP_GCC2.1.1,,,,,,,RGPD4_HUMAN,Homo sapiens (Human),protein targeting to Golgi [GO:0000042] comp106341_c0_seq1,408,39.2157,0.70308283,16,22,,1.00E-12,Q8BNA6,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_MOUSE,Mus musculus (Mouse),cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842] comp106352_c0_seq1,479,43.6326,0.61606429,15,10,,2.00E-99,O14733,Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2),Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2),GO:0005524; GO:0038095; GO:0008545; GO:0004708; GO:0002755; GO:0035666; GO:0007257; GO:0006915; GO:0005829; GO:0045087; GO:0000287; GO:0005634; GO:0018108; GO:0043525; GO:0019903; GO:0004674; GO:0004713; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124,ATP binding; Fc-epsilon receptor signaling pathway; JUN kinase kinase activity; MAP kinase kinase activity; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; activation of JUN kinase activity; apoptotic process; cytosol; innate immune response; magnesium ion binding; nucleus; peptidyl-tyrosine phosphorylation; positive regulation of neuron apoptotic process; protein phosphatase binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway,PF00069;,2.00E-72,CHOYP_MP2K7.2.2,6.00E-26,ruditapes_c12960,,,,,MP2K7_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to sorbitol [GO:0072709]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteolysis in other organism [GO:0035897]; response to heat [GO:0009408]; response to osmotic stress [GO:0006970]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403] comp106358_c0_seq1,504,42.6587,0.65584674,7,44,,7.00E-69,Q9Y2G0,Protein EFR3 homolog B,Protein EFR3 homolog B,,,,7.00E-53,CHOYP_EFR3B.1.1,,,,,,,EFR3B_HUMAN,Homo sapiens (Human),establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854] comp106358_c1_seq1,230,40.8696,0.43421873,6,0,,8.00E-06,Q6C8F7,Protein EFR3,Protein EFR3,,,,,,,,,,,,EFR3_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica), comp106361_c0_seq1,261,47.1264,0.56496786,5,0,,,,,,,,,4.00E-65,CHOYP_CLCN3.1.1,,,,,,,,, comp106361_c1_seq1,431,47.3318,0.48848947,19,5,,7.00E-60,Q5RDJ7,H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3),H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3),GO:0005524; GO:0005794; GO:0030165; GO:0015297; GO:0005769; GO:0031901; GO:0016021; GO:0005770; GO:0031902; GO:0030658; GO:0012506; GO:0005247,ATP binding; Golgi apparatus; PDZ domain binding; antiporter activity; early endosome; early endosome membrane; integral to membrane; late endosome; late endosome membrane; transport vesicle membrane; vesicle membrane; voltage-gated chloride channel activity,PF00571;PF00654;,,,,,,,,,CLCN3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp106368_c0_seq1,409,43.7653,0.89359509,11,10,,7.00E-21,Q99315,Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)],Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,,,,,,,,,YG31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp106369_c0_seq1,407,43.7346,0.47077207,10,62,,1.00E-37,Q9NVH0,Exonuclease 3'-5' domain-containing protein 2 (Exonuclease 3'-5' domain-like-containing protein 2),Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;,2.00E-13,CHOYP_LOC100553135.1.1,,,,,,,EXD2_HUMAN,Homo sapiens (Human),DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305] comp106375_c1_seq1,541,44.9168,0.29796693,9,7,,1.00E-06,A3KN33,"Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)","Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)",GO:0030054; GO:0005578; GO:0045202,cell junction; proteinaceous extracellular matrix; synapse,PF00008;PF00041;PF00054;PF02210;,,,,,,,,,EGFLA_BOVIN,Bos taurus (Bovine), comp106394_c1_seq2,550,42.7273,0.71942788,15,35,,,,,,,,,8.00E-27,CHOYP_LOC100184254.1.1,,,,,,,,, comp106398_c1_seq1,250,61.2,1.20138674,2,4,,9.00E-27,P31026,NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4),NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4),GO:0005737; GO:0006537; GO:0004354,cytoplasm; glutamate biosynthetic process; glutamate dehydrogenase (NADP+) activity,PF00208;PF02812;,,,,,,,,,DHE4_CORGL,Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025),glutamate biosynthetic process [GO:0006537] comp106401_c0_seq1,496,48.7903,1.06109247,54,0,,1.00E-06,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp106403_c0_seq1,671,40.6855,0.61918837,0,0,,2.00E-49,Q16665,Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8),Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8),GO:0001922; GO:0051879; GO:0007219; GO:0001077; GO:0003705; GO:0001076; GO:0001525; GO:0019896; GO:0003208; GO:0051216; GO:0006879; GO:0071347; GO:0021987; GO:0032963; GO:0002248; GO:0005829; GO:0048546; GO:0071542; GO:0051541; GO:0035162; GO:0001892; GO:0061030; GO:0001837; GO:0042593; GO:0001947; GO:0042541; GO:0060574; GO:0006089; GO:0007595; GO:0042789; GO:0031514; GO:0046716; GO:0032007; GO:0030502; GO:0045926; GO:2001054; GO:0043524; GO:0001755; GO:0021502; GO:0005730; GO:0005654; GO:0003151; GO:0032364; GO:0045766; GO:0032722; GO:0070101; GO:0001938; GO:0010634; GO:0045648; GO:0045821; GO:0046886; GO:0035774; GO:0002052; GO:0051000; GO:0010870; GO:0061419; GO:0030949; GO:0010575; GO:0000988; GO:0046982; GO:0043619; GO:0032909; GO:0014850; GO:0061298; GO:0043565; GO:0004871; GO:0005667; GO:0044212; GO:0010573; GO:0008542,B-1 B cell homeostasis; Hsp90 protein binding; Notch signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity; angiogenesis; axon transport of mitochondrion; cardiac ventricle morphogenesis; cartilage development; cellular iron ion homeostasis; cellular response to interleukin-1; cerebral cortex development; collagen metabolic process; connective tissue replacement involved in inflammatory response wound healing; cytosol; digestive tract morphogenesis; dopaminergic neuron differentiation; elastin metabolic process; embryonic hemopoiesis; embryonic placenta development; epithelial cell differentiation involved in mammary gland alveolus development; epithelial to mesenchymal transition; glucose homeostasis; heart looping; hemoglobin biosynthetic process; intestinal epithelial cell maturation; lactate metabolic process; lactation; mRNA transcription from RNA polymerase II promoter; motile cilium; muscle cell cellular homeostasis; negative regulation of TOR signaling cascade; negative regulation of bone mineralization; negative regulation of growth; negative regulation of mesenchymal cell apoptotic process; negative regulation of neuron apoptotic process; neural crest cell migration; neural fold elevation formation; nucleolus; nucleoplasm; outflow tract morphogenesis; oxygen homeostasis; positive regulation of angiogenesis; positive regulation of chemokine production; positive regulation of chemokine-mediated signaling pathway; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell migration; positive regulation of erythrocyte differentiation; positive regulation of glycolysis; positive regulation of hormone biosynthetic process; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of neuroblast proliferation; positive regulation of nitric-oxide synthase activity; positive regulation of receptor biosynthetic process; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation vascular endothelial growth factor production; protein binding transcription factor activity; protein heterodimerization activity; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; regulation of transforming growth factor beta2 production; response to muscle activity; retina vasculature development in camera-type eye; sequence-specific DNA binding; signal transducer activity; transcription factor complex; transcription regulatory region DNA binding; vascular endothelial growth factor production; visual learning,PF11413;PF08778;PF00989;PF08447;,8.00E-22,CHOYP_LOC101067536.1.1,,,,,,,HIF1A_HUMAN,Homo sapiens (Human),"acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; axonal transport of mitochondrion [GO:0019896]; B-1 B cell homeostasis [GO:0001922]; cardiac ventricle morphogenesis [GO:0003208]; cartilage development [GO:0051216]; cellular iron ion homeostasis [GO:0006879]; cellular response to carbon monoxide [GO:0071245]; cellular response to cobalt ion [GO:0071279]; cellular response to cyanide [GO:1903928]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucose stimulus [GO:0071333]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to light stimulus [GO:0071482]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitrite [GO:0071250]; cellular response to organic cyclic compound [GO:0071407]; cellular response to toxic substance [GO:0097237]; cerebral cortex development [GO:0021987]; collagen metabolic process [GO:0032963]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; elastin metabolic process [GO:0051541]; embryonic hemopoiesis [GO:0035162]; embryonic placenta development [GO:0001892]; epithelial cell differentiation involved in mammary gland alveolus development [GO:0061030]; epithelial to mesenchymal transition [GO:0001837]; heart looping [GO:0001947]; hemoglobin biosynthetic process [GO:0042541]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; intestinal epithelial cell maturation [GO:0060574]; iris morphogenesis [GO:0061072]; lactate metabolic process [GO:0006089]; lactation [GO:0007595]; maternal process involved in female pregnancy [GO:0060135]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of bone mineralization [GO:0030502]; negative regulation of growth [GO:0045926]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vasoconstriction [GO:0045906]; neural crest cell migration [GO:0001755]; neural fold elevation formation [GO:0021502]; outflow tract morphogenesis [GO:0003151]; oxygen homeostasis [GO:0032364]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell size [GO:0045793]; positive regulation of chemokine-mediated signaling pathway [GO:0070101]; positive regulation of chemokine production [GO:0032722]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitophagy [GO:1903599]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of aerobic respiration [GO:1903715]; regulation of cellular response to hypoxia [GO:1900037]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; regulation of transforming growth factor beta2 production [GO:0032909]; response to alkaloid [GO:0043279]; response to anesthetic [GO:0072347]; response to auditory stimulus [GO:0010996]; response to estradiol [GO:0032355]; response to fungicide [GO:0060992]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to muscle activity [GO:0014850]; response to purine-containing compound [GO:0014074]; response to salt stress [GO:0009651]; response to X-ray [GO:0010165]; retina vasculature development in camera-type eye [GO:0061298]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]; vascular endothelial growth factor production [GO:0010573]; visual learning [GO:0008542]" comp106403_c0_seq2,938,42.7505,0.64367393,25,28,,2.00E-56,Q24167,Protein similar,Protein similar,GO:0003677; GO:0071456; GO:0032869; GO:0005737; GO:0030308; GO:0005634; GO:0048477; GO:0045944; GO:0051726; GO:0006974; GO:0004871; GO:0060438; GO:0006351,"DNA binding; cellular response to hypoxia; cellular response to insulin stimulus; cytoplasm; negative regulation of cell growth; nucleus; oogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; response to DNA damage stimulus; signal transducer activity; trachea development; transcription, DNA-dependent",PF00989;PF08447;,,,,,,,,,SIMA_DROME,Drosophila melanogaster (Fruit fly),"cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; negative regulation of cell growth [GO:0030308]; oogenesis [GO:0048477]; positive regulation of autophagy [GO:0010508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell migration [GO:0030334]; regulation of innate immune response [GO:0045088]; regulation of transcription, DNA-templated [GO:0006355]; trachea development [GO:0060438]; transcription, DNA-templated [GO:0006351]" comp106414_c1_seq1,1372,36.0787,0.62946623,666,71,,,,,,,,,5.00E-22,CHOYP_ABHD2.2.2,,,,,,,,, comp106414_c1_seq2,1318,35.736,0.66724519,58,0,,3.00E-31,Q6FIF0,AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3),AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3),GO:0003677; GO:0006915; GO:0071356; GO:0005737; GO:0043066; GO:0031593; GO:0006625; GO:0043122; GO:0008270,DNA binding; apoptotic process; cellular response to tumor necrosis factor; cytoplasm; negative regulation of apoptotic process; polyubiquitin binding; protein targeting to peroxisome; regulation of I-kappaB kinase/NF-kappaB cascade; zinc ion binding,PF01754;PF01428;,5.00E-22,CHOYP_ABHD2.2.2,,,,,,,ZFAN6_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; protein targeting to peroxisome [GO:0006625]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] comp106420_c1_seq1,729,37.3114,0.23712892,24,45,,3.00E-41,Q8VD57,Vesicle transport protein SFT2B (SFT2 domain-containing protein 2),Vesicle transport protein SFT2B (SFT2 domain-containing protein 2),GO:0016021; GO:0015031; GO:0016192,integral to membrane; protein transport; vesicle-mediated transport,PF04178;,4.00E-38,CHOYP_BRAFLDRAFT_61234.1.1,,,,,,,SFT2B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp106434_c0_seq1,459,45.9695,0.46464867,9,8,,2.00E-34,P51569,Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),GO:0005794; GO:0004557; GO:0005576; GO:0016139; GO:0046477; GO:0005764; GO:0045019; GO:0051001; GO:0009311; GO:0042803; GO:0052692; GO:0005102,Golgi apparatus; alpha-galactosidase activity; extracellular region; glycoside catabolic process; glycosylceramide catabolic process; lysosome; negative regulation of nitric oxide biosynthetic process; negative regulation of nitric-oxide synthase activity; oligosaccharide metabolic process; protein homodimerization activity; raffinose alpha-galactosidase activity; receptor binding,PF16499;,,,,,,,,,AGAL_MOUSE,Mus musculus (Mouse),glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] comp106435_c0_seq1,348,41.954,0.3289997,5,7,,3.00E-27,Q2T9K6,Protein fem-1 homolog C (FEM1c) (FEM1-gamma),Protein fem-1 homolog C (FEM1c) (FEM1-gamma),GO:0005737; GO:0016567,cytoplasm; protein ubiquitination,PF12796;,9.00E-43,CHOYP_AGAP_AGAP004499.1.1,,,,,,,FEM1C_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567] comp106437_c4_seq1,290,40,0.26075579,12,0,,4.00E-06,Q6PJW8,Consortin,Consortin,GO:0005794; GO:0071253; GO:0016021; GO:0010923; GO:0019902; GO:0005886; GO:0042998; GO:0043234; GO:0005802; GO:0030133,Golgi apparatus; connexin binding; integral to membrane; negative regulation of phosphatase activity; phosphatase binding; plasma membrane; positive regulation of Golgi to plasma membrane protein transport; protein complex; trans-Golgi network; transport vesicle,PF15281;,,,,,,,,,CNST_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998] comp106439_c0_seq1,672,45.0893,0.5872101,22,23,,1.00E-18,Q66J01,GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1),GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1),GO:0006505; GO:0005783; GO:0005789; GO:0016021; GO:0006886; GO:0015798; GO:0004518; GO:0042578,GPI anchor metabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; intracellular protein transport; myo-inositol transport; nuclease activity; phosphoric ester hydrolase activity,PF07819;,,,,,,,,,PGAP1_XENLA,Xenopus laevis (African clawed frog),myo-inositol transport [GO:0015798]; protein transport [GO:0015031] comp106446_c0_seq1,489,44.7853,0.53619753,0,0,,2.00E-16,Q8K0D2,Hyaluronan-binding protein 2 (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form],Hyaluronan-binding protein 2 (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form],GO:0005576; GO:0006508; GO:0004252,extracellular region; proteolysis; serine-type endopeptidase activity,PF00008;PF00051;PF00089;,,,,,,,,,HABP2_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp106446_c0_seq2,221,46.6063,0.51991697,4,0,,5.00E-07,A5A8Y8,Epidermal growth factor-like protein 8 (EGF-like protein 8),Epidermal growth factor-like protein 8 (EGF-like protein 8),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF00008;PF07645;PF07546;,,,,,,,,,EGFL8_PIG,Sus scrofa (Pig), comp106446_c0_seq3,1527,46.4309,0.59095989,27,103,,2.00E-167,P07207,Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],GO:0005796; GO:0061382; GO:0007219; GO:0048052; GO:0007464; GO:0045466; GO:0045463; GO:0007460; GO:0007015; GO:0005912; GO:0008356; GO:0007298; GO:0005509; GO:0009986; GO:0008407; GO:0003682; GO:0042676; GO:0046667; GO:0005829; GO:0008340; GO:0046843; GO:0007391; GO:0007451; GO:0007398; GO:0035165; GO:0005788; GO:0005768; GO:0061331; GO:0035153; GO:0035214; GO:0007440; GO:0060288; GO:0030718; GO:0030708; GO:0007403; GO:0008347; GO:0035172; GO:0007157; GO:0007446; GO:0016348; GO:0048803; GO:0008587; GO:0007474; GO:0016021; GO:0035171; GO:0046331; GO:0007616; GO:0035170; GO:0007498; GO:0008045; GO:0007521; GO:0046329; GO:0045316; GO:0035157; GO:0050768; GO:0035155; GO:0000122; GO:0007400; GO:0005654; GO:0007314; GO:0030720; GO:0030713; GO:0007422; GO:1900087; GO:0045747; GO:0008284; GO:0045944; GO:0043234; GO:0045468; GO:0042686; GO:0042689; GO:0051489; GO:0040008; GO:0009608; GO:0016330; GO:0007519; GO:0035003; GO:0006351; GO:0004888; GO:0007419; GO:0048190; GO:0007473,"Golgi lumen; Malpighian tubule tip cell differentiation; Notch signaling pathway; R1/R6 cell differentiation; R3/R4 cell fate commitment; R7 cell differentiation; R8 cell development; R8 cell fate commitment; actin filament organization; adherens junction; asymmetric cell division; border follicle cell migration; calcium ion binding; cell surface; chaeta morphogenesis; chromatin binding; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; cytosol; determination of adult lifespan; dorsal appendage formation; dorsal closure; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; embryonic crystal cell differentiation; endoplasmic reticulum lumen; endosome; epithelial cell proliferation involved in Malpighian tubule morphogenesis; epithelial cell type specification, open tracheal system; eye-antennal disc development; foregut morphogenesis; formation of a compartment boundary; germ-line stem cell maintenance; germarium-derived female germ-line cyst encapsulation; glial cell fate determination; glial cell migration; hemocyte proliferation; heterophilic cell-cell adhesion; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived male genitalia morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; lamellocyte differentiation; lateral inhibition; long-term memory; lymph gland crystal cell differentiation; mesoderm development; motor neuron axon guidance; muscle cell fate determination; negative regulation of JNK cascade; negative regulation of compound eye photoreceptor development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleoplasm; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of Notch signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of R8 cell spacing in compound eye; regulation of cardioblast cell fate specification; regulation of crystal cell differentiation; regulation of filopodium assembly; regulation of growth; response to symbiont; second mitotic wave involved in compound eye morphogenesis; skeletal muscle tissue development; subapical complex; transcription, DNA-dependent; transmembrane signaling receptor activity; ventral cord development; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,1.00E-43,CHOYP_LOC100897243.1.1,,,,,,,NOTCH_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]" comp106457_c0_seq2,454,47.3568,0.78747353,1,2,,1.00E-16,P15848,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0005975; GO:0007417; GO:0030207; GO:0005788; GO:0006687; GO:0043202; GO:0007041; GO:0007040; GO:0046872; GO:0005739; GO:0043687; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; carbohydrate metabolic process; central nervous system development; chondroitin sulfate catabolic process; endoplasmic reticulum lumen; glycosphingolipid metabolic process; lysosomal lumen; lysosomal transport; lysosome organization; metal ion binding; mitochondrion; post-translational protein modification; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,6.00E-15,CHOYP_LOC100378957.1.1,,,,,,,ARSB_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; glycosphingolipid metabolic process [GO:0006687]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; positive regulation of neuron projection development [GO:0010976]; post-translational protein modification [GO:0043687]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] comp106478_c0_seq2,977,41.3511,0.09999244,26,92,,,,,,,,,,,6.00E-36,ruditapes_c9996,,,,,,, comp106478_c1_seq1,528,42.4242,0.21100993,11,45,,2.00E-64,P70353,Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC),Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC),GO:0016602; GO:0003677; GO:0005654; GO:0045893; GO:0043565; GO:0003700; GO:0005667; GO:0006351,"CCAAT-binding factor complex; DNA binding; nucleoplasm; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF00808;,4.00E-87,CHOYP_MED8B.1.1,,,,,,,NFYC_MOUSE,Mus musculus (Mouse),"positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]" comp106485_c0_seq2,1030,38.7379,0.74386795,18,53,,7.00E-45,Q8BW00,Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29),Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29),GO:0004045; GO:0005739,aminoacyl-tRNA hydrolase activity; mitochondrion,PF01195;,,,,,,,,,PTH_MOUSE,Mus musculus (Mouse),mitochondrial translation [GO:0032543] comp106488_c0_seq1,201,38.806,1.06528675,7,15,,,,,,,,,9.00E-15,CHOYP_contig_020943,,,,,,,,, comp106493_c0_seq1,603,41.9569,0.52311936,16,26,,2.00E-23,P58802,TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein),TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein),GO:0005097; GO:0005085; GO:0005902; GO:0032851,Rab GTPase activator activity; guanyl-nucleotide exchange factor activity; microvillus; positive regulation of Rab GTPase activity,PF00566;,1.00E-12,CHOYP_BRAFLDRAFT_84319.1.1,,,,,,,TB10A_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity [GO:0097202]; activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; positive regulation of proteolysis [GO:0045862]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]" comp106500_c0_seq1,349,45.2722,0.28203294,6,18,,2.00E-08,Q9JMG6,TCF3 fusion partner homolog (Protein amida),TCF3 fusion partner homolog (Protein amida),GO:0003677; GO:0006310; GO:0006281; GO:0031011; GO:0006915; GO:0097190; GO:0005737; GO:0005634; GO:0043065; GO:0046982; GO:0006355; GO:0006351,"DNA binding; DNA recombination; DNA repair; Ino80 complex; apoptotic process; apoptotic signaling pathway; cytoplasm; nucleus; positive regulation of apoptotic process; protein heterodimerization activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,2.00E-20,CHOYP_BRAFLDRAFT_130806.2.2,,,,,,,TFPT_RAT,Rattus norvegicus (Rat),"apoptotic process [GO:0006915]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; positive regulation of apoptotic process [GO:0043065]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp106509_c0_seq1,1395,45.1613,0.85660857,56,56,,2.00E-93,Q9W734,Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6),Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6),GO:0031589; GO:0003682; GO:0006955; GO:0046872; GO:0030514; GO:0010991; GO:0043066; GO:0008285; GO:0060394; GO:0030512; GO:0005634; GO:0034616; GO:0003700; GO:0005667; GO:0044212; GO:0006351; GO:0007179; GO:0030617; GO:0001657; GO:0007352,"cell-substrate adhesion; chromatin binding; immune response; metal ion binding; negative regulation of BMP signaling pathway; negative regulation of SMAD protein complex assembly; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of pathway-restricted SMAD protein phosphorylation; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; response to laminar fluid shear stress; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; ureteric bud development; zygotic specification of dorsal/ventral axis",PF03165;PF03166;,,,,,,,,,SMAD6_CHICK,Gallus gallus (Chicken),"aorta development [GO:0035904]; BMP signaling pathway [GO:0030509]; cell-substrate adhesion [GO:0031589]; coronary vasculature development [GO:0060976]; fat cell differentiation [GO:0045444]; heart valve development [GO:0003170]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway involved in spinal cord association neuron specification [GO:1902879]; negative regulation of cell proliferation in dorsal spinal cord [GO:1902832]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway [GO:1902844]; regulation of neurogenesis [GO:0050767]; response to laminar fluid shear stress [GO:0034616]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; ventricular septum development [GO:0003281]; zygotic specification of dorsal/ventral axis [GO:0007352]" comp106514_c0_seq1,484,42.7686,0.55747364,25,23,,4.00E-07,Q8BTY2,Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7),Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7),GO:0016324; GO:0060117; GO:0016323; GO:0021747; GO:0005737; GO:0005452; GO:0016021; GO:0061299; GO:0046666; GO:0006814; GO:0032420; GO:0015293,apical plasma membrane; auditory receptor cell development; basolateral plasma membrane; cochlear nucleus development; cytoplasm; inorganic anion exchanger activity; integral to membrane; retina vasculature morphogenesis in camera-type eye; retinal cell programmed cell death; sodium ion transport; stereocilium; symporter activity,PF07565;PF00955;,,,,,,,,,S4A7_MOUSE,Mus musculus (Mouse),anion transmembrane transport [GO:0098656]; auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cochlear nucleus development [GO:0021747]; regulation of intracellular pH [GO:0051453]; retinal cell programmed cell death [GO:0046666]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sodium ion transport [GO:0006814]; visual perception [GO:0007601] comp106521_c1_seq1,367,35.9673,0.85442938,0,26,,5.00E-18,Q5E9U0,Transcription factor Sp2,Transcription factor Sp2,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,SP2_BOVIN,Bos taurus (Bovine),"multicellular organism growth [GO:0035264]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp106521_c1_seq2,433,38.1062,0.90015295,1,17,,2.00E-48,Q96NI8,Zinc finger protein 570,Zinc finger protein 570,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN570_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp106524_c0_seq1,219,51.5982,0.62265449,0,42,,8.00E-08,P84755,Protease inhibitor 2 (CmPI-II) (Protease inhibitor-II),Protease inhibitor 2 (CmPI-II) (Protease inhibitor-II),GO:0004867,serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,IPK2_CENMR,Cenchritis muricatus (Beaded periwinkle), comp106528_c0_seq1,631,39.3027,0.90715958,21,93,,1.00E-61,A5WUL3,Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5),Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF06179;,,,,,,,,,MED22_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"transcription, DNA-templated [GO:0006351]" comp106543_c0_seq1,488,46.9262,0.62303176,11,0,,2.00E-24,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,1.00E-61,CHOYP_NBEL1.1.1,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp106543_c1_seq1,423,42.7896,0.6227697,12,15,,6.00E-12,E7FAW3,Neurobeachin-like protein 2,Neurobeachin-like protein 2,GO:0005783,endoplasmic reticulum,PF02138;PF15787;PF14844;PF00400;,,,,,,,,,NBEL2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp106568_c0_seq1,475,41.4737,0.2463779,9,31,,9.00E-34,Q8BYR8,Solute carrier family 41 member 2,Solute carrier family 41 member 2,GO:0008324; GO:0016021; GO:0005886,cation transmembrane transporter activity; integral to membrane; plasma membrane,PF01769;,2.00E-40,CHOYP_LOC100372696.1.2,,,,,,,S41A2_MOUSE,Mus musculus (Mouse),divalent metal ion transport [GO:0070838] comp106570_c0_seq1,388,37.3711,1.07927788,1,19,,1.00E-08,Q29YR5,Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2),Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2),GO:0004027; GO:0005783; GO:0008202; GO:0050294; GO:0000103,alcohol sulfotransferase activity; endoplasmic reticulum; steroid metabolic process; steroid sulfotransferase activity; sulfate assimilation,PF00685;,,,,,,,,,ST2B1_RAT,Rattus norvegicus (Rat),steroid metabolic process [GO:0008202]; sulfate assimilation [GO:0000103] comp106570_c0_seq2,375,38.6667,1.01543932,0,23,,4.00E-07,Q29476,Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol-sulfating phenol sulfotransferase) (P-PST),Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol-sulfating phenol sulfotransferase) (P-PST),GO:0004062; GO:0006584; GO:0005737; GO:0000166; GO:0008202,aryl sulfotransferase activity; catecholamine metabolic process; cytoplasm; nucleotide binding; steroid metabolic process,PF00685;,,,,,,,,,ST1A1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202] comp106570_c0_seq3,475,37.4737,1.10526806,0,0,,2.00E-10,O35403,Amine sulfotransferase (EC 2.8.2.3) (SULT-X2) (Sulfotransferase 3A1) (ST3A1),Amine sulfotransferase (EC 2.8.2.3) (SULT-X2) (Sulfotransferase 3A1) (ST3A1),GO:0047685; GO:0005737,amine sulfotransferase activity; cytoplasm,PF00685;,,,,,,,,,ST3A1_MOUSE,Mus musculus (Mouse),sulfation [GO:0051923] comp106571_c0_seq1,463,44.0605,0.64221753,6,6,,3.00E-26,P79171,Aminopeptidase N (AP-N) (fAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (fAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0019048; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; modulation by virus of host morphology or physiology; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_FELCA,Felis catus (Cat) (Felis silvestris catus),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp106571_c1_seq1,268,44.7761,0.30098321,2,8,,5.00E-10,P91887,Aminopeptidase N (AP-N) (EC 3.4.11.2) (Apn1) (Microsomal aminopeptidase),Aminopeptidase N (AP-N) (EC 3.4.11.2) (Apn1) (Microsomal aminopeptidase),GO:0004177; GO:0031225; GO:0008237; GO:0005886; GO:0006508; GO:0008270,aminopeptidase activity; anchored to membrane; metallopeptidase activity; plasma membrane; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_PLUXY,Plutella xylostella (Diamondback moth) (Plutella maculipennis), comp106605_c0_seq1,541,42.8835,0.41060746,1,14,,2.00E-35,Q54B10,NADPH oxidoreductase A (EC 1.6.-.-),NADPH oxidoreductase A (EC 1.6.-.-),GO:0010181; GO:0050661; GO:0003958; GO:0005829; GO:0050660; GO:0005506; GO:0016709; GO:0030587,"FMN binding; NADP binding; NADPH-hemoprotein reductase activity; cytosol; flavin adenine dinucleotide binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; sorocarp development",PF00667;PF00258;PF00175;,,,,,,,,,REDA_DICDI,Dictyostelium discoideum (Slime mold),sorocarp development [GO:0030587] comp106609_c0_seq4,331,43.5045,0.71120415,0,45,,,,,,,,,,,2.00E-23,ruditapes_c15086,,,,,,, comp106614_c0_seq2,617,40.5186,0.39984577,2,16,,3.00E-57,P97878,Exocyst complex component 5 (71 kDa component of rsec6/8 secretory complex) (Exocyst complex component Sec10) (p71),Exocyst complex component 5 (71 kDa component of rsec6/8 secretory complex) (Exocyst complex component Sec10) (p71),GO:0005829; GO:0006887; GO:0015031; GO:0048278,cytosol; exocytosis; protein transport; vesicle docking,PF07393;,7.00E-22,CHOYP_BRAFLDRAFT_125658.1.1,,,,,,,EXOC5_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; protein transport [GO:0015031]; vesicle docking [GO:0048278] comp106632_c0_seq1,490,36.9388,0.25147352,26,94,,1.00E-31,Q8R3N1,Nucleolar protein 14 (Nucleolar complex protein 14),Nucleolar protein 14 (Nucleolar complex protein 14),GO:0005730; GO:0006364; GO:0042274; GO:0032040; GO:0030515,nucleolus; rRNA processing; ribosomal small subunit biogenesis; small-subunit processome; snoRNA binding,PF04147;,6.00E-60,CHOYP_LOC100368659.1.2,,,,,,,NOP14_MOUSE,Mus musculus (Mouse),maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274] comp106637_c0_seq1,376,40.6915,0.71108185,28,14,,1.00E-22,Q5SVZ6,Zinc finger MYM-type protein 1,Zinc finger MYM-type protein 1,GO:0003676; GO:0005634; GO:0008270,nucleic acid binding; nucleus; zinc ion binding,PF05699;PF14291;PF06467;,,,,,,,,,ZMYM1_HUMAN,Homo sapiens (Human), comp106639_c0_seq1,826,40.1937,0.40424951,24,53,,4.00E-112,O08700,Vacuolar protein sorting-associated protein 45 (rVps45),Vacuolar protein sorting-associated protein 45 (rVps45),GO:0005794; GO:0000139; GO:0010008; GO:0016021; GO:0015031; GO:0006904,Golgi apparatus; Golgi membrane; endosome membrane; integral to membrane; protein transport; vesicle docking involved in exocytosis,PF00995;,1.00E-76,CHOYP_VPS45.1.1,,,,,,,VPS45_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp106639_c1_seq1,310,38.0645,0.09319845,5,22,,2.00E-09,Q54QC8,Protein transport protein sec1,Protein transport protein sec1,GO:0006928; GO:0015031; GO:0006904,cellular component movement; protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SEC1_DICDI,Dictyostelium discoideum (Slime mold),cell motility [GO:0048870]; cellular response to osmotic stress [GO:0071470]; contractile vacuole discharge [GO:0070177]; plasma membrane organization [GO:0007009]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp106646_c0_seq2,580,45,0.37821156,0,0,,7.00E-17,O93614,Rap1 GTPase-GDP dissociation stimulator 1-A (Rap1gds1-A protein) (RalB-binding protein A) (XsmgGDS-A) (smgGDS-A),Rap1 GTPase-GDP dissociation stimulator 1-A (Rap1gds1-A protein) (RalB-binding protein A) (XsmgGDS-A) (smgGDS-A),GO:0005096; GO:0005737; GO:0005856; GO:0043547; GO:0007264,GTPase activator activity; cytoplasm; cytoskeleton; positive regulation of GTPase activity; small GTPase mediated signal transduction,PF00514;,,,,,,,,,GDS1A_XENLA,Xenopus laevis (African clawed frog),positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] comp106658_c0_seq1,236,48.7288,0.72924386,8,10,,,,,,,,,1.00E-13,CHOYP_LOC100377321.1.1,1.00E-11,ruditapes_c15192,,,,,,, comp106658_c1_seq1,487,53.1828,0.40739587,5,39,,3.00E-48,P58195,Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1),Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1),GO:0042609; GO:0003677; GO:0005794; GO:0001077; GO:0017124; GO:0006915; GO:0005509; GO:0005829; GO:0051607; GO:0005154; GO:0031012; GO:0006955; GO:0005887; GO:0045121; GO:0045071; GO:0005730; GO:0017128; GO:2000373; GO:0045089; GO:0060368; GO:0033003,CD4 receptor binding; DNA binding; Golgi apparatus; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; SH3 domain binding; apoptotic process; calcium ion binding; cytosol; defense response to virus; epidermal growth factor receptor binding; extracellular matrix; immune response; integral to plasma membrane; membrane raft; negative regulation of viral genome replication; nucleolus; phospholipid scramblase activity; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; positive regulation of innate immune response; regulation of Fc receptor mediated stimulatory signaling pathway; regulation of mast cell activation,PF03803;,2.00E-54,CHOYP_contig_045072,,,,,,,PLS1_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; immune response [GO:0006955]; negative regulation of viral genome replication [GO:0045071]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782]; phospholipid scrambling [GO:0017121]; phospholipid transport [GO:0015914]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; regulation of mast cell activation [GO:0033003] comp106668_c0_seq1,258,43.0233,0.70862898,2,13,,1.00E-09,Q54NZ4,AP-4 complex subunit sigma (AP-4 adapter complex subunit sigma) (Adapter-related protein complex 4 subunit sigma) (Sigma subunit of AP-4) (Sigma4-adaptin),AP-4 complex subunit sigma (AP-4 adaptor complex subunit sigma) (Adaptor-related protein complex 4 subunit sigma) (Sigma subunit of AP-4) (Sigma4-adaptin),GO:0030659; GO:0008565,cytoplasmic vesicle membrane; protein transporter activity,PF01217;,,,,,,,,,AP4S_DICDI,Dictyostelium discoideum (Slime mold), comp106668_c1_seq1,476,33.4034,0.54399067,9,125,,1.00E-18,Q9Y587,AP-4 complex subunit sigma-1 (AP-4 adapter complex subunit sigma-1) (Adapter-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin),AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin),GO:0005794; GO:0005905; GO:0008565; GO:0005215,Golgi apparatus; coated pit; protein transporter activity; transporter activity,PF01217;,9.00E-13,CHOYP_AP4S1.1.1,1.00E-14,ruditapes_c13221,,,,,AP4S1_HUMAN,Homo sapiens (Human), comp106670_c0_seq1,537,42.6443,0.32860093,7,0,,2.00E-07,Q5T089,MORN repeat-containing protein 1,MORN repeat-containing protein 1,,,PF02493;,,,,,,,,,MORN1_HUMAN,Homo sapiens (Human), comp106683_c1_seq1,242,43.3884,0.61855602,2,4,,2.00E-15,Q5ZJB4,Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA),Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA),GO:0005524; GO:0007252; GO:0008384; GO:0002755; GO:0035419; GO:0007250; GO:0071356; GO:0005829; GO:0045087; GO:0005634; GO:0005886; GO:0045944; GO:0046982; GO:0042803; GO:0035681; GO:0034134; GO:0035682; GO:0034138; GO:0034142; GO:0034146; GO:0034154,ATP binding; I-kappaB phosphorylation; IkappaB kinase activity; MyD88-dependent toll-like receptor signaling pathway; activation of MAPK activity involved in innate immune response; activation of NF-kappaB-inducing kinase activity; cellular response to tumor necrosis factor; cytosol; innate immune response; nucleus; plasma membrane; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; protein homodimerization activity; toll-like receptor 15 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 21 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 7 signaling pathway,PF12179;PF00069;,,,,,,,,,IKKA_CHICK,Gallus gallus (Chicken),cellular response to tumor necrosis factor [GO:0071356]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp106700_c0_seq1,213,57.7465,0.79471248,0,15,,2.00E-12,P0AFR6,Uncharacterized protein YciO,Uncharacterized protein YciO,GO:0003725,double-stranded RNA binding,PF01300;,,,,,,,,,YCIO_SHIFL,Shigella flexneri, comp106705_c0_seq1,572,40.5594,0.53006637,20,0,,1.00E-31,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,5.00E-11,CHOYP_LOC100207121.8.9,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp106706_c0_seq1,413,49.8789,0.32442153,12,1,,7.00E-35,Q68F64,Protein unc-45 homolog B (Unc-45B),Protein unc-45 homolog B (Unc-45B),GO:0030154; GO:0005829; GO:0007517,cell differentiation; cytosol; muscle organ development,PF13181;PF11701;,4.00E-23,CHOYP_UN45B.1.1,,,,,,,UN45B_XENLA,Xenopus laevis (African clawed frog),cell differentiation [GO:0030154]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517] comp106716_c1_seq1,234,36.7521,1.15386723,1,11,,5.00E-07,Q5FVH0,Complement C1q tumor necrosis factor-related protein 5,Complement C1q tumor necrosis factor-related protein 5,GO:0005581,collagen,PF00386;PF01391;,,,,,,,,,C1QT5_RAT,Rattus norvegicus (Rat), comp106727_c0_seq1,842,44.4181,0.64334236,36,9,,,,,,,,,7.00E-30,CHOYP_PLD1.1.1,,,,,,,,, comp106727_c1_seq1,419,44.6301,0.63592256,7,19,,2.00E-45,Q13393,Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),GO:0005794; GO:0000139; GO:0070290; GO:0007265; GO:0006935; GO:0050830; GO:0005789; GO:0005768; GO:0031902; GO:0016042; GO:0005765; GO:0048471; GO:0006654; GO:0006655; GO:0035091; GO:0004630; GO:0044281,Golgi apparatus; Golgi membrane; NAPE-specific phospholipase D activity; Ras protein signal transduction; chemotaxis; defense response to Gram-positive bacterium; endoplasmic reticulum membrane; endosome; late endosome membrane; lipid catabolic process; lysosomal membrane; perinuclear region of cytoplasm; phosphatidic acid biosynthetic process; phosphatidylglycerol biosynthetic process; phosphatidylinositol binding; phospholipase D activity; small molecule metabolic process,PF00169;PF00614;PF13091;PF00787;,,,,,,,,,PLD1_HUMAN,Homo sapiens (Human),cell motility [GO:0048870]; chemotaxis [GO:0006935]; inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of microvillus assembly [GO:0032534]; regulation of phagocytosis [GO:0050764]; small GTPase mediated signal transduction [GO:0007264] comp106732_c0_seq1,228,43.4211,0.28110197,3,4,,,,,,,,,,,9.00E-26,ruditapes_c29520,,,,,,, comp106734_c0_seq1,413,62.954,1.25679308,0,13,,6.00E-22,P95231,Serine acetyltransferase (SAT) (EC 2.3.1.30),Serine acetyltransferase (SAT) (EC 2.3.1.30),GO:0006535; GO:0005829; GO:0009001,cysteine biosynthetic process from serine; cytosol; serine O-acetyltransferase activity,PF00132;,,,,,,,,,CYSE_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),cysteine biosynthetic process from serine [GO:0006535] comp106737_c0_seq2,649,48.5362,0.55040453,4,0,,1.00E-18,Q39575,"Dynein gamma chain, flagellar outer arm","Dynein gamma chain, flagellar outer arm",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHG_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158] comp106737_c1_seq1,1136,46.3028,0.43097726,5,0,,4.00E-150,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,1.00E-167,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp106741_c0_seq1,358,47.486,0.6046363,3,2,,5.00E-10,Q08345,Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a),Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a),GO:0005524; GO:0060444; GO:0005518; GO:0043583; GO:0007566; GO:0030198; GO:0005576; GO:0005887; GO:0007595; GO:0060749; GO:0046872; GO:0008285; GO:0038083; GO:0038062; GO:0001558; GO:0001952; GO:0010715; GO:0014909; GO:0061302; GO:0044319,"ATP binding; branching involved in mammary gland duct morphogenesis; collagen binding; ear development; embryo implantation; extracellular matrix organization; extracellular region; integral to plasma membrane; lactation; mammary gland alveolus development; metal ion binding; negative regulation of cell proliferation; peptidyl-tyrosine autophosphorylation; protein tyrosine kinase collagen receptor activity; regulation of cell growth; regulation of cell-matrix adhesion; regulation of extracellular matrix disassembly; smooth muscle cell migration; smooth muscle cell-matrix adhesion; wound healing, spreading of cells",PF00754;PF07714;,,,,,,,,,DDR1_HUMAN,Homo sapiens (Human),"branching involved in mammary gland duct morphogenesis [GO:0060444]; cell adhesion [GO:0007155]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; extracellular matrix organization [GO:0030198]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell proliferation [GO:0008285]; organ regeneration [GO:0031100]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; skin development [GO:0043588]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; wound healing, spreading of cells [GO:0044319]" comp106769_c0_seq1,852,42.6056,0.37103139,66,28,,3.00E-21,Q9UL68,Myelin transcription factor 1-like protein (MyT1-L) (MyT1L),Myelin transcription factor 1-like protein (MyT1-L) (MyT1L),GO:0003677; GO:0030154; GO:0007399; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; cell differentiation; nervous system development; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF08474;PF01530;,,,,,,,,,MYT1L_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]" comp106796_c1_seq1,448,41.2946,0.42011905,19,26,,4.00E-18,Q53TQ3,INO80 complex subunit D,INO80 complex subunit D,GO:0006310; GO:0006281; GO:0005634; GO:0006355; GO:0006351,"DNA recombination; DNA repair; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13891;,8.00E-45,CHOYP_INO80D.1.1,,,,,,,IN80D_HUMAN,Homo sapiens (Human),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp106805_c0_seq1,315,65.0794,1.05334395,0,19,,3.00E-21,P39979,D-amino-acid N-acetyltransferase HPA3 (DNT) (EC 2.3.1.36) (Histone and other protein acetyltransferase 3),D-amino-acid N-acetyltransferase HPA3 (DNT) (EC 2.3.1.36) (EC 2.3.1.48) (Histone and other protein acetyltransferase 3),GO:0046416; GO:0047812; GO:0005737; GO:0005634,D-amino acid metabolic process; D-amino-acid N-acetyltransferase activity; cytoplasm; nucleus,PF00583;,,,,,,,,,HPA3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular detoxification of nitrogen compound [GO:0070458]; D-amino acid metabolic process [GO:0046416] comp106815_c0_seq1,546,44.8718,0.77011521,6,19,,1.00E-33,P31228,D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),GO:0003884; GO:0008445; GO:0005777,D-amino-acid oxidase activity; D-aspartate oxidase activity; peroxisome,PF01266;,,,,,,,,,OXDD_BOVIN,Bos taurus (Bovine),D-amino acid metabolic process [GO:0046416] comp106827_c1_seq1,469,36.2473,0.78160001,6,41,,,,,,,,,,,3.00E-23,ruditapes_c8881,,,,,,, comp106836_c0_seq1,497,39.839,0.41478565,4,81,,5.00E-50,Q28C22,2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-),2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-),GO:0031418; GO:0005506; GO:0016706,"L-ascorbic acid binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",,,,,,,,,,OGFD2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp106838_c1_seq1,1050,43.2381,0.57219821,56,20,,6.00E-57,Q9D5R3,Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41),Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41),GO:0005814; GO:0042384; GO:0048278,centriole; cilium assembly; vesicle docking,,1.00E-47,CHOYP_LOC100375266.1.1,,,,,,,CCD41_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; establishment of centrosome localization [GO:0051660]; protein localization to centrosome [GO:0071539]; vesicle docking [GO:0048278] comp106868_c0_seq1,581,42.1687,0.31751322,51,9,,7.00E-10,Q5BE65,3-ketodihydrosphingosine reductase tsc10 (EC 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase),3-ketodihydrosphingosine reductase tsc10 (EC 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase),GO:0047560; GO:0005789; GO:0016021; GO:0006665,3-dehydrosphinganine reductase activity; endoplasmic reticulum membrane; integral to membrane; sphingolipid metabolic process,PF00106;,5.00E-17,CHOYP_DHI1L.1.1,,,,,,,TSC10_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),3-keto-sphinganine metabolic process [GO:0006666] comp106868_c1_seq1,826,40.3148,0.44796397,45,0,,5.00E-45,A4IGM4,Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3),Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF00106;,,,,,,,,,DHI1L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp106899_c0_seq1,307,39.7394,0.3310973,1,19,,7.00E-33,Q9CPW2,"Adrenodoxin-like protein, mitochondrial (Ferredoxin-1-like protein)","Adrenodoxin-like protein, mitochondrial (Ferredoxin-1-like protein)",GO:0051537; GO:0009055; GO:0046872; GO:0005759; GO:0005739; GO:0055114,"2 iron, 2 sulfur cluster binding; electron carrier activity; metal ion binding; mitochondrial matrix; mitochondrion; oxidation-reduction process",PF00111;,5.00E-26,CHOYP_DVIR_GJ13593.1.1,,,,,,,ADXL_MOUSE,Mus musculus (Mouse),oxidation-reduction process [GO:0055114] comp106901_c0_seq1,421,46.5558,0.22157008,9,0,,3.00E-12,A9CPT4,Tudor domain-containing protein 1,Tudor domain-containing protein 1,GO:0043046; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_ORYLA,Oryzias latipes (Japanese rice fish) (Japanese killifish),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp106901_c0_seq2,280,46.0714,0.27215844,2,0,,2.00E-06,Q7ZT42,Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (4SNc-Tudor domain protein) (p100 co-activator),Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (4SNc-Tudor domain protein) (p100 co-activator),GO:0016442; GO:0005737; GO:0031047; GO:0004518; GO:0003676; GO:0090305,RISC complex; cytoplasm; gene silencing by RNA; nuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF00565;PF00567;,,,,,,,,,SND1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gene silencing by RNA [GO:0031047] comp106916_c0_seq1,813,45.5105,0.55985253,32,2,,3.00E-88,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,4.00E-103,CHOYP_LOC100747565.2.2,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp106928_c0_seq1,400,42.75,0.71864248,14,7,,5.00E-33,Q8BLB0,Zinc finger protein 3 (Zfp-3),Zinc finger protein 3 (Zfp-3),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,2.00E-15,CHOYP_GZF1.2.2,,,,,,,ZFP3_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp106931_c1_seq1,222,42.7928,0.19787447,1,3,,1.00E-07,Q9D4H2,GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1),GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1),GO:0000139; GO:0005886; GO:0000042,Golgi membrane; plasma membrane; protein targeting to Golgi,PF01465;,,,,,,,,,GCC1_MOUSE,Mus musculus (Mouse),protein targeting to Golgi [GO:0000042] comp106947_c0_seq1,372,44.3548,0.32912003,13,10,,3.00E-08,Q9FFF9,Anaphase-promoting complex subunit 1 (Cyclosome subunit 1) (Protein EMBRYO DEFECTIVE 2771),Anaphase-promoting complex subunit 1 (Cyclosome subunit 1) (Protein EMBRYO DEFECTIVE 2771),GO:0005680; GO:0010252; GO:0051301; GO:0009793; GO:0009553; GO:0007067; GO:0048481; GO:0016567,anaphase-promoting complex; auxin homeostasis; cell division; embryo development ending in seed dormancy; embryo sac development; mitosis; ovule development; protein ubiquitination,PF12859;,,,,,,,,,APC1_ARATH,Arabidopsis thaliana (Mouse-ear cress),auxin homeostasis [GO:0010252]; cell division [GO:0051301]; embryo development ending in seed dormancy [GO:0009793]; embryo sac development [GO:0009553]; mitotic nuclear division [GO:0007067]; plant ovule development [GO:0048481]; protein ubiquitination [GO:0016567] comp106947_c1_seq1,381,46.7192,0.33912726,15,40,,5.00E-30,P53995,Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),GO:0005680; GO:0051301; GO:0007067; GO:0070979,anaphase-promoting complex; cell division; mitosis; protein K11-linked ubiquitination,PF12859;PF01851;,,,,,,,,,APC1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979] comp106948_c1_seq1,487,44.7639,0.4236129,28,23,,1.00E-07,Q8N2E2,von Willebrand factor D and EGF domain-containing protein,von Willebrand factor D and EGF domain-containing protein,GO:0005576,extracellular region,PF12661;PF00094;,,,,,,,,,VWDE_HUMAN,Homo sapiens (Human), comp106950_c0_seq2,938,36.4606,0.67623534,0,0,,9.00E-17,O75896,Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2),Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2),GO:0007049; GO:0048469; GO:0008283; GO:0007267; GO:0071609; GO:0006954; GO:0032618; GO:0005739; GO:0001779; GO:0051881; GO:2000377,cell cycle; cell maturation; cell proliferation; cell-cell signaling; chemokine (C-C motif) ligand 5 production; inflammatory response; interleukin-15 production; mitochondrion; natural killer cell differentiation; regulation of mitochondrial membrane potential; regulation of reactive oxygen species metabolic process,PF15000;,,,,,,,,,TUSC2_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; cell cycle [GO:0007049]; cell maturation [GO:0048469]; cell proliferation [GO:0008283]; chemokine (C-C motif) ligand 5 production [GO:0071609]; inflammatory response [GO:0006954]; interleukin-15 production [GO:0032618]; natural killer cell differentiation [GO:0001779]; negative regulation of interleukin-17 production [GO:0032700]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of interleukin-10 production [GO:0032733]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to defense-related host reactive oxygen species production [GO:0052567] comp106953_c0_seq1,262,49.6183,0.44859328,4,15,,3.00E-34,Q2YDD4,Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11),Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11),GO:0016021; GO:0046873; GO:0006829,integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,1.00E-26,CHOYP_NEMVEDRAFT_V1G167638.1.1,,,,,,,S39AB_BOVIN,Bos taurus (Bovine),zinc II ion transmembrane transport [GO:0071577] comp106960_c0_seq1,438,41.3242,0.43262113,5,30,,1.00E-06,Q8R502,Leucine-rich repeat-containing protein 8C (Protein AD158),Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF13855;PF12534;,,,,,,,,,LRC8C_MOUSE,Mus musculus (Mouse),anion transmembrane transport [GO:0098656]; fat cell differentiation [GO:0045444] comp106966_c1_seq1,272,48.8971,0.49390084,3,8,,8.00E-30,Q9Y6J0,Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),GO:0016235; GO:0007166; GO:0016568; GO:0005737; GO:0005634; GO:0004864,aggresome; cell surface receptor signaling pathway; chromatin modification; cytoplasm; nucleus; protein phosphatase inhibitor activity,PF09047;,5.00E-19,CHOYP_CABIN1.1.1,,,,,,,CABIN_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823] comp106980_c2_seq1,265,54.3396,0.92380247,3,3,,4.00E-54,Q6A8Q7,"1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE)","1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE)",GO:0003844; GO:0043169; GO:0005978; GO:0004553,"1,4-alpha-glucan branching enzyme activity; cation binding; glycogen biosynthetic process; hydrolase activity, hydrolyzing O-glycosyl compounds",PF00128;PF02806;PF02922;,,,,,,,,,GLGB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glycogen biosynthetic process [GO:0005978] comp106982_c0_seq1,203,54.1872,1.08046316,0,0,,6.00E-08,P44023,Uncharacterized protein HI_0594,Uncharacterized protein HI_0594,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF03606;,,,,,,,,,Y594_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),anion transmembrane transport [GO:0098656] comp106988_c0_seq1,297,42.4242,0.61954964,0,17,,1.00E-12,Q6IS41,Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier homolog),Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier homolog),GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,2.00E-13,CHOYP_S2545.1.2,,,,,,,S2547_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transmembrane transport [GO:0055085] comp106991_c0_seq1,314,44.9045,0.76087728,5,26,,9.00E-08,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp106996_c1_seq1,538,44.052,0.5000731,15,9,,6.00E-60,A2ATU0,"Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)","Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)",GO:0006091; GO:0006096; GO:0005739; GO:0004591; GO:0030976; GO:0006099,generation of precursor metabolites and energy; glycolysis; mitochondrion; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF00676;PF16870;PF02779;,1.00E-61,CHOYP_DHTK1.1.1,,,,,,,DHTK1_MOUSE,Mus musculus (Mouse),generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; hematopoietic progenitor cell differentiation [GO:0002244]; tricarboxylic acid cycle [GO:0006099] comp107001_c0_seq1,547,42.0475,0.46725216,14,18,,4.00E-09,Q00WL5,"Lon protease homolog, mitochondrial (EC 3.4.21.-)","Lon protease homolog, mitochondrial (EC 3.4.21.53)",GO:0005524; GO:0006200; GO:0004176; GO:0034599; GO:0051131; GO:0006515; GO:0005759; GO:0070407; GO:0090296; GO:0043565; GO:0004252,ATP binding; ATP catabolic process; ATP-dependent peptidase activity; cellular response to oxidative stress; chaperone-mediated protein complex assembly; misfolded or incompletely synthesized protein catabolic process; mitochondrial matrix; oxidation-dependent protein catabolic process; regulation of mitochondrial DNA replication; sequence-specific DNA binding; serine-type endopeptidase activity,PF00004;PF05362;PF02190;,2.00E-16,CHOYP_LONM.1.1,,,,,,,LONM_OSTTA,Ostreococcus tauri,cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; oxidation-dependent protein catabolic process [GO:0070407]; regulation of mitochondrial DNA replication [GO:0090296] comp107001_c1_seq1,431,40.3712,0.39952653,11,34,,2.00E-34,P36776,"Lon protease homolog, mitochondrial (EC 3.4.21.-) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)","Lon protease homolog, mitochondrial (EC 3.4.21.-) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)",GO:0043531; GO:0005524; GO:0004176; GO:0051880; GO:0007568; GO:0034599; GO:0051131; GO:0006515; GO:0032042; GO:0070362; GO:0070361; GO:0042645; GO:0070407; GO:0051260; GO:0090296; GO:0010044; GO:0009725; GO:0001666; GO:0043565; GO:0004252; GO:0003697; GO:0003727,ADP binding; ATP binding; ATP-dependent peptidase activity; G-quadruplex DNA binding; aging; cellular response to oxidative stress; chaperone-mediated protein complex assembly; misfolded or incompletely synthesized protein catabolic process; mitochondrial DNA metabolic process; mitochondrial heavy strand promoter anti-sense binding; mitochondrial light strand promoter anti-sense binding; mitochondrial nucleoid; oxidation-dependent protein catabolic process; protein homooligomerization; regulation of mitochondrial DNA replication; response to aluminum ion; response to hormone stimulus; response to hypoxia; sequence-specific DNA binding; serine-type endopeptidase activity; single-stranded DNA binding; single-stranded RNA binding,PF00004;PF05362;PF02190;,,,,,,,,,LONM_HUMAN,Homo sapiens (Human),aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; oxidation-dependent protein catabolic process [GO:0070407]; protein homooligomerization [GO:0051260]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of mitochondrial DNA replication [GO:0090296]; response to aluminum ion [GO:0010044]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666] comp107007_c0_seq3,453,45.4746,0.48556386,2,15,,2.00E-54,Q9VEX0,Extracellular sulfatase SULF-1 homolog (DmSulf-1) (EC 3.1.6.-),Extracellular sulfatase SULF-1 homolog (DmSulf-1) (EC 3.1.6.-),GO:0005795; GO:0009986; GO:0005783; GO:0046872; GO:0008045; GO:0042059; GO:0045879; GO:0045880; GO:0030111; GO:0017015; GO:0008484; GO:0016201,Golgi stack; cell surface; endoplasmic reticulum; metal ion binding; motor neuron axon guidance; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of smoothened signaling pathway; positive regulation of smoothened signaling pathway; regulation of Wnt receptor signaling pathway; regulation of transforming growth factor beta receptor signaling pathway; sulfuric ester hydrolase activity; synaptic target inhibition,PF12548;PF00884;,4.00E-49,CHOYP_SULF1.1.1,,,,,,,SULF1_DROME,Drosophila melanogaster (Fruit fly),heparin metabolic process [GO:0030202]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of Wnt signaling pathway [GO:0030178]; pattern specification process [GO:0007389]; positive regulation of smoothened signaling pathway [GO:0045880]; synaptic target inhibition [GO:0016201] comp107017_c0_seq1,410,46.8293,0.85484909,15,10,,6.00E-11,O75385,Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1),Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1),GO:0005524; GO:0007265; GO:0070969; GO:0005776; GO:0000045; GO:0048675; GO:0031669; GO:0021707; GO:0030659; GO:0005829; GO:0048671; GO:0043005; GO:0031175; GO:0031102; GO:0043025; GO:0016239; GO:0034045; GO:0046777; GO:0008104; GO:0004674; GO:0021933; GO:0031623; GO:0051386; GO:0042594,ATP binding; Ras protein signal transduction; ULK1-ATG13-FIP200 complex; autophagic vacuole; autophagic vacuole assembly; axon extension; cellular response to nutrient levels; cerebellar granule cell differentiation; cytoplasmic vesicle membrane; cytosol; negative regulation of collateral sprouting; neuron projection; neuron projection development; neuron projection regeneration; neuronal cell body; positive regulation of macroautophagy; pre-autophagosomal structure membrane; protein autophosphorylation; protein localization; protein serine/threonine kinase activity; radial glia guided migration of cerebellar granule cell; receptor internalization; regulation of neurotrophin TRK receptor signaling pathway; response to starvation,PF12063;PF00069;,,,3.00E-22,ruditapes_c11660,,,,,ULK1_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; cellular response to nutrient levels [GO:0031669]; macroautophagy [GO:0016236]; negative regulation of protein complex assembly [GO:0031333]; neuron projection development [GO:0031175]; neuron projection regeneration [GO:0031102]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; protein autophosphorylation [GO:0046777]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; response to starvation [GO:0042594]; signal transduction [GO:0007165] comp107017_c1_seq1,589,47.3684,1.03189598,12,65,,3.00E-69,Q14164,Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i),Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i),GO:0005524; GO:0008384; GO:0004704; GO:0016605; GO:0035666; GO:0005829; GO:0010008; GO:0045087; GO:0008630; GO:0032480; GO:0043123; GO:0034138; GO:0034142,ATP binding; IkappaB kinase activity; NF-kappaB-inducing kinase activity; PML body; TRIF-dependent toll-like receptor signaling pathway; cytosol; endosome membrane; innate immune response; intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of type I interferon production; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway,PF00069;,1.00E-37,CHOYP_TBK1.4.5,,,,,,,IKKE_HUMAN,Homo sapiens (Human),cellular response to virus [GO:0098586]; immune response [GO:0006955]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of type I interferon production [GO:0032480]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; response to interferon-beta [GO:0035456]; response to type I interferon [GO:0034340]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] comp107021_c0_seq1,359,47.3538,0.30100568,10,0,,2.00E-39,Q8CBE3,WD repeat-containing protein 37,WD repeat-containing protein 37,,,PF00400;,2.00E-44,CHOYP_WDR37.1.1,,,,,,,WDR37_MOUSE,Mus musculus (Mouse),maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] comp107021_c0_seq3,254,46.063,0,0,0,,4.00E-18,Q8CBE3,WD repeat-containing protein 37,WD repeat-containing protein 37,,,PF00400;,,,,,,,,,WDR37_MOUSE,Mus musculus (Mouse),maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] comp107026_c0_seq1,252,40.4762,0.81614188,3,0,,,,,,,,,2.00E-11,CHOYP_LOC100377651.1.1,,,,,,,,, comp107031_c0_seq3,1308,40.8257,0.52419939,7,29,,0,Q9JJ31,Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1),Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1),GO:0031466; GO:0005737; GO:0051480; GO:0005634; GO:0005886; GO:0000209; GO:0006970; GO:0006511; GO:0004842; GO:0005000,Cul5-RING ubiquitin ligase complex; cytoplasm; cytosolic calcium ion homeostasis; nucleus; plasma membrane; protein polyubiquitination; response to osmotic stress; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; vasopressin receptor activity,PF00888;PF10557;,0,CHOYP_LOC100371275.1.1,,,,,,,CUL5_RAT,Rattus norvegicus (Rat),protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to osmotic stress [GO:0006970] comp107038_c0_seq1,436,44.9541,0.56975528,16,28,,3.00E-11,Q499Z3,Schlafen-like protein 1,Schlafen-like protein 1,GO:0005524,ATP binding,PF04326;,,,,,,,,,SLNL1_HUMAN,Homo sapiens (Human), comp107041_c0_seq1,368,40.4891,1.24382941,0,23,,1.00E-23,O54750,Cytochrome P450 2J6 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ6),Cytochrome P450 2J6 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ6),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2J6_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; epoxygenase P450 pathway [GO:0019373]; linoleic acid metabolic process [GO:0043651] comp107041_c0_seq2,327,40.6728,1.29977906,1,2,,3.00E-24,O54749,Cytochrome P450 2J5 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ5),Cytochrome P450 2J5 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ5),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2J5_MOUSE,Mus musculus (Mouse),angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; arachidonic acid metabolic process [GO:0019369]; positive regulation of estrogen secretion [GO:2000863]; regulation of systemic arterial blood pressure by hormone [GO:0001990]; renal tubular secretion [GO:0097254] comp107041_c1_seq1,237,43.038,0.73914359,3,13,,9.00E-17,Q95078,Cytochrome P450 18a1 (EC 1.14.-.-) (CYPXVIIIA1),Cytochrome P450 18a1 (EC 1.14.-.-) (CYPXVIIIA1),GO:0007304; GO:0046344; GO:0005789; GO:0020037; GO:0007480; GO:0016021; GO:0005506; GO:0016705; GO:0035210; GO:0035074; GO:0008395,"chorion-containing eggshell formation; ecdysteroid catabolic process; endoplasmic reticulum membrane; heme binding; imaginal disc-derived leg morphogenesis; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; prepupal development; pupation; steroid hydroxylase activity",PF00067;,,,,,,,,,CP18A_DROME,Drosophila melanogaster (Fruit fly),chorion-containing eggshell formation [GO:0007304]; ecdysteroid catabolic process [GO:0046344]; imaginal disc-derived leg morphogenesis [GO:0007480]; metamorphosis [GO:0007552]; prepupal development [GO:0035210]; pupation [GO:0035074]; steroid biosynthetic process [GO:0006694] comp107047_c0_seq1,634,42.429,0.49339672,27,19,,2.00E-08,Q9TZM3,"Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)","Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)",GO:0005524; GO:0005525; GO:0005794; GO:0048846; GO:0034613; GO:0046872; GO:0043025; GO:0004674; GO:0034976; GO:0006979; GO:0007264; GO:0048489,ATP binding; GTP binding; Golgi apparatus; axon extension involved in axon guidance; cellular protein localization; metal ion binding; neuronal cell body; protein serine/threonine kinase activity; response to endoplasmic reticulum stress; response to oxidative stress; small GTPase mediated signal transduction; synaptic vesicle transport,PF12796;PF16095;PF13855;PF00069;PF08477;,,,,,,,,,LRK1_CAEEL,Caenorhabditis elegans,axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489] comp107055_c0_seq1,708,37.8531,0.45890059,1,23,,2.00E-25,Q6P6Y1,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,,,,,,,,,,,,K1468_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp107055_c0_seq2,587,36.7973,0.47525957,0,0,,5.00E-27,Q08BT5,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,,,,6.00E-35,CHOYP_K1468.1.1,,,,,,,K1468_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp107063_c0_seq1,465,51.1828,0.82361639,26,1,,1.00E-28,Q5RHP9,Uncharacterized protein C1orf173,Glutamate-rich protein 3,,,PF15257;,2.00E-41,CHOYP_LOC100179357.3.6,,,,,,,CA173_HUMAN,Homo sapiens (Human), comp107066_c1_seq1,888,43.2432,0.89346847,34,11,,9.00E-14,Q9UI42,Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3),Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3),GO:0005576; GO:0016573; GO:0004181; GO:0006508; GO:0008270,extracellular region; histone acetylation; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;PF02244;,,,,,,,,,CBPA4_HUMAN,Homo sapiens (Human),histone acetylation [GO:0016573] comp107088_c1_seq1,304,48.6842,0.22426713,8,9,,3.00E-42,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,2.00E-57,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp107089_c0_seq1,931,44.6831,0.56056325,0,0,,5.00E-06,Q9EPX2,Papilin,Papilin,GO:0005604; GO:0004222; GO:0004867; GO:0008270,basement membrane; metalloendopeptidase activity; serine-type endopeptidase inhibitor activity; zinc ion binding,PF05986;PF07679;PF00047;PF00014;PF08686;PF00090;,,,,,,,,,PPN_MOUSE,Mus musculus (Mouse), comp107089_c0_seq2,1427,44.9194,0.55813981,0,0,,5.00E-51,Q9UPZ6,Thrombospondin type-1 domain-containing protein 7A,Thrombospondin type-1 domain-containing protein 7A,GO:0001525; GO:0030154; GO:0005576; GO:0016021; GO:0005886,angiogenesis; cell differentiation; extracellular region; integral to membrane; plasma membrane,PF00090;,,,,,,,,,THS7A_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell differentiation [GO:0030154] comp107097_c0_seq2,836,44.0191,0.5281558,12,73,,5.00E-06,Q32L50,Somatomedin-B and thrombospondin type-1 domain-containing protein (RPE-spondin),Somatomedin-B and thrombospondin type-1 domain-containing protein (RPE-spondin),GO:0006955; GO:0030247; GO:0005578; GO:0005044,immune response; polysaccharide binding; proteinaceous extracellular matrix; scavenger receptor activity,PF00090;,,,,,,,,,SBSPO_BOVIN,Bos taurus (Bovine),immune response [GO:0006955] comp107125_c0_seq1,383,40.47,0.639365,9,10,,7.00E-11,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp107137_c1_seq1,233,42.0601,0.53062202,1,12,,8.00E-08,Q09621,Beta-lactamase domain-containing protein 2,Beta-lactamase domain-containing protein 2,GO:0016021,integral to membrane,PF00144;,,,,,,,,,LACT2_CAEEL,Caenorhabditis elegans, comp107154_c2_seq1,591,39.7631,0.90087214,2,61,,1.00E-23,O08590,Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1),Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1),GO:0007568; GO:0052595; GO:0009308; GO:0052594; GO:0007155; GO:0009986; GO:0005507; GO:0042755; GO:0005615; GO:0016021; GO:0043231; GO:0002523; GO:0052596; GO:0005886; GO:0002675; GO:0010828; GO:0002687; GO:0008131; GO:0042803; GO:0048038; GO:0008217; GO:0052593,aging; aliphatic-amine oxidase activity; amine metabolic process; aminoacetone:oxygen oxidoreductase(deaminating) activity; cell adhesion; cell surface; copper ion binding; eating behavior; extracellular space; integral to membrane; intracellular membrane-bounded organelle; leukocyte migration involved in inflammatory response; phenethylamine:oxygen oxidoreductase (deaminating) activity; plasma membrane; positive regulation of acute inflammatory response; positive regulation of glucose transport; positive regulation of leukocyte migration; primary amine oxidase activity; protein homodimerization activity; quinone binding; regulation of blood pressure; tryptamine:oxygen oxidoreductase (deaminating) activity,PF01179;PF02727;PF02728;,,,,,,,,,AOC3_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]; eating behavior [GO:0042755]; leukocyte migration involved in inflammatory response [GO:0002523]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of glucose transport [GO:0010828]; positive regulation of leukocyte migration [GO:0002687]; regulation of blood pressure [GO:0008217]; response to immobilization stress [GO:0035902] comp107158_c0_seq1,467,48.394,0.55411099,12,49,,3.00E-55,Q6PDJ6,F-box only protein 42,F-box only protein 42,,,PF12937;PF07646;,2.00E-72,CHOYP_FBX42.1.1,,,,,,,FBX42_MOUSE,Mus musculus (Mouse), comp107161_c0_seq1,228,25.4386,1.10098272,18,16,,,,,,,,,1.00E-13,CHOYP_LOC100561123.22.28,1.00E-12,ruditapes_c376,,,,,,, comp107167_c0_seq1,423,44.6809,0.33827406,7,8,,3.00E-47,Q5ZJD8,Transmembrane protein 68,Transmembrane protein 68,GO:0016021; GO:0016746,"integral to membrane; transferase activity, transferring acyl groups",PF01553;,1.00E-22,CHOYP_LOC100374932.1.1,,,,,,,TMM68_CHICK,Gallus gallus (Chicken),metabolic process [GO:0008152] comp107177_c0_seq1,398,42.7136,0.65547009,14,75,,1.00E-29,Q5ZIH9,Coiled-coil domain-containing protein 174,Coiled-coil domain-containing protein 174,,,PF13300;,,,,,,,,,CC019_CHICK,Gallus gallus (Chicken), comp107195_c0_seq1,489,35.7873,0.65333607,6,16,,3.00E-08,Q9HAZ2,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;PF13912;,,,,,,,,,PRD16_HUMAN,Homo sapiens (Human),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp107200_c0_seq1,577,46.1005,0.65723092,29,53,,4.00E-13,P51830,Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10),Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (AC9) (Adenylyl cyclase type 10) (ACTP10),GO:0005524; GO:0007190; GO:0004016; GO:0016021; GO:0035556; GO:0046872; GO:0005886,ATP binding; activation of adenylate cyclase activity; adenylate cyclase activity; integral to membrane; intracellular signal transduction; metal ion binding; plasma membrane,PF00211;,3.00E-20,CHOYP_APLD.1.1,,,,,,,ADCY9_MOUSE,Mus musculus (Mouse),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933] comp107201_c0_seq3,1204,41.6113,0.44409401,0,5,,3.00E-97,Q7TML3,Solute carrier family 35 member F2,Solute carrier family 35 member F2,GO:0016021; GO:0006810,integral to membrane; transport,PF06027;,,,,,,,,,S35F2_MOUSE,Mus musculus (Mouse),transport [GO:0006810] comp107207_c0_seq2,726,38.292,0.41946054,7,24,,3.00E-13,O08839,Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1),Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1),GO:0043679; GO:0044300; GO:0006897; GO:0007275; GO:0042692; GO:0005634; GO:0043547; GO:0045807; GO:0008021; GO:0043196,axon terminus; cerebellar mossy fiber; endocytosis; multicellular organismal development; muscle cell differentiation; nucleus; positive regulation of GTPase activity; positive regulation of endocytosis; synaptic vesicle; varicosity,PF03114;PF14604;,,,,,,,,,BIN1_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; lipid tube assembly [GO:0060988]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of endocytosis [GO:0045807]; positive regulation of GTPase activity [GO:0043547]; regulation of cell cycle arrest [GO:0071156]; regulation of neuron differentiation [GO:0045664] comp107216_c1_seq1,679,43.5935,0.46875102,17,5,,3.00E-100,Q92830,Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (HsGCN5) (Lysine acetyltransferase 2A) (STAF97),Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (HsGCN5) (Lysine acetyltransferase 2A) (STAF97),GO:0005671; GO:0010484; GO:0030914; GO:0008283; GO:0003682; GO:0006338; GO:0044154; GO:0043997; GO:0016578; GO:0001701; GO:0022037; GO:0030901; GO:0072686; GO:0019048; GO:0035264; GO:0001843; GO:0042981; GO:0031647; GO:0006357; GO:0001756; GO:0021537; GO:0003713; GO:0033276; GO:0006366,Ada2/Gcn5/Ada3 transcription activator complex; H3 histone acetyltransferase activity; STAGA complex; cell proliferation; chromatin binding; chromatin remodeling; histone H3-K14 acetylation; histone acetyltransferase activity (H4-K12 specific); histone deubiquitination; in utero embryonic development; metencephalon development; midbrain development; mitotic spindle; modulation by virus of host morphology or physiology; multicellular organism growth; neural tube closure; regulation of apoptotic process; regulation of protein stability; regulation of transcription from RNA polymerase II promoter; somitogenesis; telencephalon development; transcription coactivator activity; transcription factor TFTC complex; transcription from RNA polymerase II promoter,PF00583;PF00439;PF06466;,4.00E-146,CHOYP_KAT2B.1.1,,,,,,,KAT2A_HUMAN,Homo sapiens (Human),"alpha-tubulin acetylation [GO:0071929]; cardiac muscle cell differentiation [GO:0055007]; cell proliferation [GO:0008283]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; intracellular distribution of mitochondria [GO:0048312]; in utero embryonic development [GO:0001701]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; positive regulation of cell projection organization [GO:0031346]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone acetylation [GO:0035066]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; somitogenesis [GO:0001756]; telencephalon development [GO:0021537]; transcription from RNA polymerase II promoter [GO:0006366]; viral process [GO:0016032]" comp107218_c0_seq1,561,49.5544,0.7958631,4,63,,,,,,,,,3.00E-51,CHOYP_DFA_05420.1.1,,,,,,,,, comp107223_c0_seq1,364,55.4945,1.14510668,0,21,,2.00E-15,Q92JJ2,CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase) (PGP synthase),CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase) (PGP synthase),GO:0008444; GO:0016021; GO:0006655; GO:0005886,CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity; integral to membrane; phosphatidylglycerol biosynthetic process; plasma membrane,PF01066;,,,,,,,,,PGSA_RICCN,Rickettsia conorii (strain ATCC VR-613 / Malish 7),phosphatidylglycerol biosynthetic process [GO:0006655] comp107223_c2_seq1,217,61.7512,1.39077914,0,4,,6.00E-28,Q6A908,Ribosomal protein S12 methylthiotransferase RimO (S12 MTTase) (S12 methylthiotransferase) (EC 2.-.-.-) (Ribosome maturation factor RimO),Ribosomal protein S12 methylthiotransferase RimO (S12 MTTase) (S12 methylthiotransferase) (EC 2.8.4.4) (Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase) (Ribosome maturation factor RimO),GO:0051539; GO:0009451; GO:0005737; GO:0005506; GO:0018339; GO:0016740,"4 iron, 4 sulfur cluster binding; RNA modification; cytoplasm; iron ion binding; peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid; transferase activity",PF04055;PF00919;,,,,,,,,,RIMO_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid [GO:0018339]; RNA modification [GO:0009451] comp107235_c0_seq1,759,43.3465,0.53973331,16,34,,8.00E-67,Q96JG6,Coiled-coil domain-containing protein 132,Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50),,,PF10474;PF10475;,2.00E-18,CHOYP_CC132.1.1,,,,,,,CC132_HUMAN,Homo sapiens (Human),endocytic recycling [GO:0032456]; protein transport [GO:0015031] comp107239_c2_seq1,420,36.4286,0.14393244,1,41,,4.00E-06,A0MS83,Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89),Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89),GO:0003677; GO:0030097; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; hemopoiesis; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN148_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"hemopoiesis [GO:0030097]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp107244_c0_seq1,428,43.6916,0.25426881,0,0,,9.00E-06,Q5U597,Src kinase-associated phosphoprotein 2-B,Src kinase-associated phosphoprotein 2-B,GO:0042113; GO:0005737; GO:0005543,B cell activation; cytoplasm; phospholipid binding,PF00169;PF00018;,,,,,,,,,SKA2B_XENLA,Xenopus laevis (African clawed frog),B cell activation [GO:0042113] comp107244_c0_seq6,483,43.6853,0.22004095,0,0,,9.00E-06,Q5U597,Src kinase-associated phosphoprotein 2-B,Src kinase-associated phosphoprotein 2-B,GO:0042113; GO:0005737; GO:0005543,B cell activation; cytoplasm; phospholipid binding,PF00169;PF00018;,,,,,,,,,SKA2B_XENLA,Xenopus laevis (African clawed frog),B cell activation [GO:0042113] comp107286_c0_seq1,402,40.796,0.30740083,32,0,,2.00E-43,Q8GW29,Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG7 (EC 3.2.2.n1) (Protein LONELY GUY 7),Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG7 (EC 3.2.2.n1) (Protein LONELY GUY 7),GO:0009691; GO:0005829; GO:0016799; GO:0005634,"cytokinin biosynthetic process; cytosol; hydrolase activity, hydrolyzing N-glycosyl compounds; nucleus",PF03641;,,,,,,,,,LOG7_ARATH,Arabidopsis thaliana (Mouse-ear cress),cytokinin biosynthetic process [GO:0009691] comp107298_c0_seq1,356,37.0787,0.98370466,6,6,,3.00E-12,Q24563,Dopamine receptor 2,Dopamine receptor 2 (Dopamine 1-like receptor 2),GO:0008227; GO:0007191; GO:0004935; GO:0071875; GO:0001588; GO:0005887; GO:0030285,"G-protein coupled amine receptor activity; adenylate cyclase-activating dopamine receptor signaling pathway; adrenergic receptor activity; adrenergic receptor signaling pathway; dopamine neurotransmitter receptor activity, coupled via Gs; integral to plasma membrane; integral to synaptic vesicle membrane",PF00001;,5.00E-15,CHOYP_DOPR2.1.1,,,,,,,DOPR2_DROME,Drosophila melanogaster (Fruit fly),"adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; age-dependent response to oxidative stress [GO:0001306]; dopamine receptor signaling pathway [GO:0007212]; G-protein coupled receptor signaling pathway [GO:0007186]; learning [GO:0007612]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; synaptic transmission, dopaminergic [GO:0001963]" comp107302_c0_seq2,523,47.2275,0.48867751,8,24,,4.00E-40,Q54468,Chitobiase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase),Chitobiase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase),GO:0004563; GO:0006032; GO:0042597; GO:0030247; GO:0000272,beta-N-acetylhexosaminidase activity; chitin catabolic process; periplasmic space; polysaccharide binding; polysaccharide catabolic process,PF03173;PF00728;PF02838;,,,,,,,,,CHB_SERMA,Serratia marcescens,chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] comp107304_c0_seq1,348,43.1034,0.26001332,13,9,,5.00E-21,Q9BXW9,Fanconi anemia group D2 protein (Protein FACD2),Fanconi anemia group D2 protein (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0005654; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; nucleoplasm; response to gamma radiation; synapsis,PF14631;,4.00E-16,CHOYP_BRAFLDRAFT_216683.1.1,,,,,,,FACD2_HUMAN,Homo sapiens (Human),gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp107304_c1_seq2,278,45.6835,0.56137547,2,0,,4.00E-13,Q80V62,Fanconi anemia group D2 protein homolog (Protein FACD2),Fanconi anemia group D2 protein homolog (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0007275; GO:0005634; GO:0006974; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; multicellular organismal development; nucleus; response to DNA damage stimulus; response to gamma radiation; synapsis,PF14631;,,,,,,,,,FACD2_MOUSE,Mus musculus (Mouse),brain morphogenesis [GO:0048854]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; gamete generation [GO:0007276]; neuronal stem cell population maintenance [GO:0097150]; regulation of CD40 signaling pathway [GO:2000348]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp107306_c0_seq1,396,43.4343,0.32211159,2,64,,2.00E-59,Q32KJ6,N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase),N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase),GO:0043890; GO:0005764; GO:0046872,N-acetylgalactosamine-6-sulfatase activity; lysosome; metal ion binding,PF00884;,1.00E-61,CHOYP_LOC588014.1.1,,,,,,,GALNS_RAT,Rattus norvegicus (Rat),metabolic process [GO:0008152] comp107319_c0_seq2,409,47.1883,0.57361514,5,11,,6.00E-34,Q91ZH7,Abhydrolase domain-containing protein 3 (EC 3.1.1.-) (Lung alpha/beta hydrolase 3) (MmLABH3),Phospholipase ABHD3 (EC 3.1.1.32) (EC 3.1.1.4) (Abhydrolase domain-containing protein 3) (Lung alpha/beta hydrolase 3) (MmLABH3),GO:0004091; GO:0016021,carboxylesterase activity; integral to membrane,PF00561;,,,,,,,,,ABHD3_MOUSE,Mus musculus (Mouse),phosphatidylcholine metabolic process [GO:0046470] comp107320_c1_seq2,1396,45.5587,0.30538569,45,18,,3.00E-54,Q8CE72,Uncharacterized protein C5orf42 homolog,Uncharacterized protein C5orf42 homolog,GO:0016021,integral to membrane,PF15392;,,,,,,,,,CE042_MOUSE,Mus musculus (Mouse),cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; palate development [GO:0060021]; protein localization to ciliary transition zone [GO:1904491]; ventricular septum development [GO:0003281] comp107323_c1_seq3,334,42.515,0.75250828,6,0,,4.00E-14,Q5R9A7,Integral membrane protein GPR155,Integral membrane protein GPR155,GO:0016021; GO:0035556; GO:0055085,integral to membrane; intracellular signal transduction; transmembrane transport,PF00610;PF03547;,1.00E-16,CHOYP_LOC661299.1.1,,,,,,,GP155_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] comp107326_c0_seq1,289,38.4083,0.95458681,6,19,,8.00E-11,Q9H4Q4,PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),GO:0003677; GO:0046872; GO:0008168; GO:0022008; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; neurogenesis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD12_HUMAN,Homo sapiens (Human),"neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp107341_c0_seq1,746,41.555,0.62312424,5,80,,3.00E-110,Q5RBZ8,Transmembrane protein 41B,Transmembrane protein 41B,GO:0016021,integral to membrane,PF09335;,5.00E-82,CHOYP_LOC590316.1.1,,,,,,,TM41B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),nervous system development [GO:0007399] comp107365_c0_seq1,269,49.0706,1.05591521,0,33,,5.00E-13,P48999,Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34),Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34),GO:0004051; GO:0005829; GO:0005506; GO:0019370; GO:0002540; GO:0005641; GO:0016363; GO:0031965,arachidonate 5-lipoxygenase activity; cytosol; iron ion binding; leukotriene biosynthetic process; leukotriene production involved in inflammatory response; nuclear envelope lumen; nuclear matrix; nuclear membrane,PF00305;PF01477;,,,,,,,,,LOX5_MOUSE,Mus musculus (Mouse),acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; inflammatory response [GO:0006954]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxygenase pathway [GO:0019372]; positive regulation of vasoconstriction [GO:0045907]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233] comp107371_c1_seq1,270,47.037,0.87420554,12,11,,3.00E-09,Q6UX65,DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77),DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77),GO:0005794; GO:0030262; GO:0016021; GO:0005765; GO:0005764,Golgi apparatus; apoptotic nuclear changes; integral to membrane; lysosomal membrane; lysosome,PF10277;,,,,,,,,,DRAM2_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] comp107372_c0_seq1,306,47.3856,0.64275525,3,13,,2.00E-32,Q6ZT07,TBC1 domain family member 9 (TBC1 domain family member 9A),TBC1 domain family member 9 (TBC1 domain family member 9A),GO:0005097; GO:0005509; GO:0032851,Rab GTPase activator activity; calcium ion binding; positive regulation of Rab GTPase activity,PF02893;PF00566;,2.00E-44,CHOYP_BRAFLDRAFT_153908.2.2,,,,,,,TBCD9_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp107376_c0_seq1,275,42.5455,0.4056491,17,24,,2.00E-25,Q5TM74,"Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)","Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)",GO:0005524; GO:0002161; GO:0005739; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; mitochondrion; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00133;,,,,,,,,,SYVM_MACMU,Macaca mulatta (Rhesus macaque),valyl-tRNA aminoacylation [GO:0006438] comp107381_c1_seq1,254,35.4331,1.0154463,2,8,,5.00E-08,C8V4D4,SCF E3 ubiquitin ligase complex F-box protein grrA (F-box and leucine-rich repeat protein grrA) (F-box/LRR-repeat protein grrA) (SCF substrate adapter protein grrA),SCF E3 ubiquitin ligase complex F-box protein grrA (F-box and leucine-rich repeat protein grrA) (F-box/LRR-repeat protein grrA) (SCF substrate adapter protein grrA),GO:0019005; GO:0030437; GO:0005737; GO:0031176; GO:0007126,"SCF ubiquitin ligase complex; ascospore formation; cytoplasm; endo-1,4-beta-xylanase activity; meiosis",PF12937;,,,,,,,,,GRRA_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),ascospore formation [GO:0030437]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to methylmercury [GO:0071406]; mitotic cell cycle arrest in response to pheromone [GO:0000751]; protein polyubiquitination [GO:0000209]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp107390_c0_seq1,973,42.9599,0.51380788,35,54,,9.00E-103,Q96Q83,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 3) (DEPC-1) (Prostate cancer antigen 1),Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 3) (hABH3) (DEPC-1) (Prostate cancer antigen 1),GO:0006307; GO:0043734; GO:0031418; GO:0008283; GO:0051747; GO:0008198; GO:0005739; GO:0005654; GO:0035552,DNA dealkylation involved in DNA repair; DNA-N1-methyladenine dioxygenase activity; L-ascorbic acid binding; cell proliferation; cytosine C-5 DNA demethylase activity; ferrous iron binding; mitochondrion; nucleoplasm; oxidative single-stranded DNA demethylation,PF13532;,4.00E-78,CHOYP_ALKBH3.1.1,,,,,,,ALKB3_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553] comp107392_c0_seq1,338,46.4497,0.99349616,2,28,,,,,,,,,4.00E-15,CHOYP_BRAFLDRAFT_76550.6.21,6.00E-11,ruditapes_c4462,,,,,,, comp107402_c0_seq1,268,49.2537,0.61811522,1,34,,2.00E-38,Q92002,Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) (aMIb),Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) (aMIb),GO:0005524; GO:0005737; GO:0003774; GO:0016459; GO:0060171,ATP binding; cytoplasm; motor activity; myosin complex; stereocilium membrane,PF00612;PF00063;PF06017;,5.00E-38,CHOYP_MYO1C.2.3,,,,,,,MYO1C_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana), comp107406_c2_seq1,829,50.1809,0.44719893,56,39,,,,,,,,,6.00E-12,CHOYP_contig_018711,,,,,,,,, comp107422_c1_seq1,677,39.291,0.40242253,39,377,,3.00E-63,Q96FN9,Probable D-tyrosyl-tRNA(Tyr) deacylase 2 (EC 3.1.-.-) (D-tyrosyl-tRNA deacylase 2),Probable D-tyrosyl-tRNA(Tyr) deacylase 2 (EC 3.1.-.-) (D-tyrosyl-tRNA deacylase 2),GO:0019478; GO:0005737; GO:0016788,"D-amino acid catabolic process; cytoplasm; hydrolase activity, acting on ester bonds",PF02580;,,,,,,,,,DTD2_HUMAN,Homo sapiens (Human),D-amino acid catabolic process [GO:0019478]; tRNA metabolic process [GO:0006399] comp107445_c1_seq1,432,38.4259,0.12660887,4,23,,2.00E-07,Q0R4F1,ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1),ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006310; GO:0006281; GO:0005739; GO:0005634; GO:0000723,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA recombination; DNA repair; mitochondrion; nucleus; telomere maintenance,PF02689;PF05970;,,,,,,,,,PIF1_XENLA,Xenopus laevis (African clawed frog),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] comp107448_c1_seq1,417,38.1295,0.4634173,22,22,,9.00E-18,Q0P5H1,Prenylcysteine oxidase-like (EC 1.8.3.-),Prenylcysteine oxidase-like (EC 1.8.3.-),GO:0005576; GO:0030328; GO:0001735,extracellular region; prenylcysteine catabolic process; prenylcysteine oxidase activity,PF07156;,,,,,,,,,PCYXL_BOVIN,Bos taurus (Bovine),prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328] comp107463_c0_seq1,920,41.413,0.56487382,58,0,,2.00E-13,Q6INN8,Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-),Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-),GO:0003723; GO:0051607; GO:0045087; GO:0008152; GO:0046872; GO:0005634; GO:0008081; GO:0045088,RNA binding; defense response to virus; innate immune response; metabolic process; metal ion binding; nucleus; phosphoric diester hydrolase activity; regulation of innate immune response,PF01966;PF07647;,2.00E-19,CHOYP_SAMH1.10.12,,,,,,,SAMH1_XENLA,Xenopus laevis (African clawed frog),dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; innate immune response [GO:0045087]; regulation of innate immune response [GO:0045088] comp107485_c0_seq1,598,38.1271,0.61821386,27,64,,6.00E-17,Q9Y7Y3,Uncharacterized RNA-binding protein C365.04c,Uncharacterized RNA-binding protein C365.04c,GO:0003723; GO:0005730; GO:0000166; GO:0042254,RNA binding; nucleolus; nucleotide binding; ribosome biogenesis,PF00076;,1.00E-24,CHOYP_LOC580669.1.1,,,,,,,YGR4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254] comp107491_c0_seq1,748,39.0374,0.85632775,128,360,,1.00E-09,Q98943,Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],GO:0006915; GO:0004197; GO:0005622; GO:0006508; GO:0042981,apoptotic process; cysteine-type endopeptidase activity; intracellular; proteolysis; regulation of apoptotic process,PF00619;,,,,,,,,,CASP2_CHICK,Gallus gallus (Chicken),regulation of apoptotic process [GO:0042981] comp107499_c0_seq1,228,38.1579,0.63541733,1,13,,6.00E-16,Q7SYJ9,Sperm-associated antigen 7 homolog,Sperm-associated antigen 7 homolog,GO:0003676,nucleic acid binding,PF01424;,4.00E-38,CHOYP_SPAG7.1.1,,,,,,,SPAG7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp107502_c0_seq1,391,46.5473,0.61568604,9,22,,1.00E-12,Q8JZP3,Kelch-like protein 2,Kelch-like protein 2,GO:0031463; GO:0003779; GO:0005737; GO:0005829; GO:0030027; GO:0042803; GO:0016567; GO:0001726; GO:0001725,Cul3-RING ubiquitin ligase complex; actin binding; cytoplasm; cytosol; lamellipodium; protein homodimerization activity; protein ubiquitination; ruffle; stress fiber,PF07707;PF00651;PF01344;,,,,,,,,,KLHL2_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp107506_c1_seq1,299,41.806,0.46584372,5,15,,1.00E-07,Q8BMT9,Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Skinny hedgehog protein),Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Skinny hedgehog protein),GO:0005525; GO:0005789; GO:0016021; GO:0007275; GO:0016409; GO:0018345; GO:0007224,GTP binding; endoplasmic reticulum membrane; integral to membrane; multicellular organismal development; palmitoyltransferase activity; protein palmitoylation; smoothened signaling pathway,PF03062;,,,,,,,,,HHAT_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; smoothened signaling pathway [GO:0007224] comp107510_c0_seq1,656,40.8537,0.56134785,43,14,,,,,,,,,5.00E-12,CHOYP_BLM.1.1,,,,,,,,, comp107518_c1_seq1,481,40.9563,0.25125213,19,27,,,,,,,,,3.00E-25,CHOYP_DICPUDRAFT_50844.1.1,,,,,,,,, comp107521_c1_seq1,725,51.0345,0.83915871,37,22,,3.00E-37,Q03567,Uncharacterized transporter C38C10.2,Uncharacterized transporter slc-17.2,GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF07690;,9.00E-22,CHOYP_LOC100378615.1.2,,,,,,,YLD2_CAEEL,Caenorhabditis elegans,anion transport [GO:0006820]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085] comp107532_c0_seq1,481,49.4802,0.75072891,23,18,,2.00E-25,Q9BZ29,Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1),Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1),GO:0005089; GO:0007596; GO:0005829; GO:0012505; GO:0016020; GO:0005543; GO:0007264,Rho guanyl-nucleotide exchange factor activity; blood coagulation; cytosol; endomembrane system; membrane; phospholipid binding; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;PF00169;,4.00E-17,CHOYP_DOCK9.1.2,,,,,,,DOCK9_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; small GTPase mediated signal transduction [GO:0007264] comp107537_c1_seq1,273,61.1722,1.39046642,2,2,,2.00E-06,O34817,HTH-type transcriptional repressor YvoA,HTH-type transcriptional repressor YvoA,GO:0003677; GO:0003700; GO:0006351,"DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00392;PF07702;,,,,,,,,,YVOA_BACSU,Bacillus subtilis (strain 168),"transcription, DNA-templated [GO:0006351]" comp107543_c0_seq2,1921,37.064,0.45545036,61,92,,1.00E-30,P47825,Transcription initiation factor TFIID subunit 4 (110 kDa TBP-associated factor) (Transcription initiation factor TFIID 110 kDa subunit) (TAFII-110) (p110),Transcription initiation factor TFIID subunit 4 (110 kDa TBP-associated factor) (Transcription initiation factor TFIID 110 kDa subunit) (TAFII-110) (p110),GO:0003677; GO:0051123; GO:0048813; GO:0007517; GO:0045944; GO:0003700; GO:0005669,DNA binding; RNA polymerase II transcriptional preinitiation complex assembly; dendrite morphogenesis; muscle organ development; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor TFIID complex,PF05236;PF07531;,1.00E-25,CHOYP_SI_DKEY-219C3.2.1.1,,,,,,,TAF4_DROME,Drosophila melanogaster (Fruit fly),"dendrite morphogenesis [GO:0048813]; muscle organ development [GO:0007517]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp107571_c0_seq1,808,44.5545,0.43500193,50,28,,1.00E-30,Q96FG2,ELMO domain-containing protein 3 (RNA-binding motif and ELMO domain-containing protein 1) (RNA-binding motif protein 29) (RNA-binding protein 29),ELMO domain-containing protein 3 (RNA-binding motif and ELMO domain-containing protein 1) (RNA-binding motif protein 29) (RNA-binding protein 29),GO:0005856; GO:0006909,cytoskeleton; phagocytosis,PF04727;,,,,,,,,,ELMD3_HUMAN,Homo sapiens (Human), comp107582_c0_seq1,276,40.5797,1.24296503,7,46,,3.00E-15,Q5R9I0,Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1),Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1),GO:0052595; GO:0009308; GO:0052594; GO:0007155; GO:0009986; GO:0005507; GO:0016021; GO:0052596; GO:0005886; GO:0008131; GO:0048038; GO:0052593,aliphatic-amine oxidase activity; amine metabolic process; aminoacetone:oxygen oxidoreductase(deaminating) activity; cell adhesion; cell surface; copper ion binding; integral to membrane; phenethylamine:oxygen oxidoreductase (deaminating) activity; plasma membrane; primary amine oxidase activity; quinone binding; tryptamine:oxygen oxidoreductase (deaminating) activity,PF01179;PF02727;PF02728;,,,,,,,,,AOC3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),amine metabolic process [GO:0009308]; cell adhesion [GO:0007155] comp107585_c0_seq1,729,43.3471,0.71838744,20,60,,2.00E-57,Q9BUP3,Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2),Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2),GO:0001525; GO:0006915; GO:0030154; GO:0005737; GO:0019048; GO:0043066; GO:0005635; GO:0051170; GO:0016491; GO:0045765; GO:0006357; GO:0003713,angiogenesis; apoptotic process; cell differentiation; cytoplasm; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; nuclear envelope; nuclear import; oxidoreductase activity; regulation of angiogenesis; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity,PF13460;,,,,,,,,,HTAI2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; negative regulation of apoptotic process [GO:0043066]; nuclear import [GO:0051170]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; viral process [GO:0016032] comp107604_c0_seq2,1000,43.1,0.56659612,9,196,,2.00E-104,Q14DK5,HHIP-like protein 1,HHIP-like protein 1,GO:0005975; GO:0005576; GO:0016020; GO:0016901; GO:0048038; GO:0005044,"carbohydrate metabolic process; extracellular region; membrane; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; quinone binding; scavenger receptor activity",PF03024;PF07995;PF00530;,3.00E-35,CHOYP_LOC100313632.1.1,,,,,,,HIPL1_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975] comp107608_c0_seq1,408,48.2843,0.54837376,12,0,,2.00E-26,Q6N021,Methylcytosine dioxygenase TET2 (EC 1.14.11.n2),Methylcytosine dioxygenase TET2 (EC 1.14.11.n2),GO:0007049; GO:0080182; GO:0001822; GO:0046872; GO:0070579; GO:0030099; GO:0045944; GO:0009791; GO:0006493,cell cycle; histone H3-K4 trimethylation; kidney development; metal ion binding; methylcytosine dioxygenase activity; myeloid cell differentiation; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein O-linked glycosylation,PF12851;,2.00E-33,CHOYP_TET1.1.1,,,,,,,TET2_HUMAN,Homo sapiens (Human),5-methylcytosine catabolic process [GO:0006211]; cell cycle [GO:0007049]; cytosine metabolic process [GO:0019858]; DNA demethylation [GO:0080111]; hematopoietic stem cell homeostasis [GO:0061484]; hemoglobin metabolic process [GO:0020027]; histone H3-K4 trimethylation [GO:0080182]; kidney development [GO:0001822]; liver morphogenesis [GO:0072576]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein O-linked glycosylation [GO:0006493]; response to organic cyclic compound [GO:0014070]; spleen development [GO:0048536] comp107625_c1_seq1,375,45.3333,0.20828288,5,16,,1.00E-34,P35475,Alpha-L-iduronidase (EC 3.2.1.76),Alpha-L-iduronidase (EC 3.2.1.76),GO:0003940; GO:0000902; GO:0048878; GO:0030207; GO:0030135; GO:0030209; GO:0005984; GO:0035108; GO:0043202; GO:0007040; GO:0048705,L-iduronidase activity; cell morphogenesis; chemical homeostasis; chondroitin sulfate catabolic process; coated vesicle; dermatan sulfate catabolic process; disaccharide metabolic process; limb morphogenesis; lysosomal lumen; lysosome organization; skeletal system morphogenesis,PF01229;,,,,,,,,,IDUA_HUMAN,Homo sapiens (Human),chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate catabolic process [GO:0030209]; disaccharide metabolic process [GO:0005984]; glycosaminoglycan catabolic process [GO:0006027] comp107625_c2_seq1,306,46.4052,0.3672288,6,5,,1.00E-29,Q01634,Alpha-L-iduronidase (EC 3.2.1.76),Alpha-L-iduronidase (EC 3.2.1.76),GO:0003940; GO:0005975; GO:0030209; GO:0005764,L-iduronidase activity; carbohydrate metabolic process; dermatan sulfate catabolic process; lysosome,PF01229;,6.00E-19,CHOYP_IDUA.3.3,,,,,,,IDUA_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),carbohydrate metabolic process [GO:0005975]; dermatan sulfate catabolic process [GO:0030209] comp107656_c0_seq1,249,49.7992,0.3906313,6,7,,3.00E-18,B4JWL5,Protein arginine N-methyltransferase 7 (EC 2.1.1.-),Protein arginine N-methyltransferase 7 (EC 2.1.1.-),GO:0005737; GO:0035243,cytoplasm; protein-arginine omega-N symmetric methyltransferase activity,,,,,,,,,,ANM7_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi),peptidyl-arginine methylation [GO:0018216] comp107657_c1_seq1,448,33.9286,0.55189037,12,65,,2.00E-15,Q6AY64,UPF0669 protein C6orf120 homolog,UPF0669 protein C6orf120 homolog,GO:0006915; GO:0005576,apoptotic process; extracellular region,PF17065;,,,,,,,,,CF120_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915] comp107661_c0_seq1,274,41.2409,0.79788297,5,13,,,,,,,,,7.00E-24,CHOYP_LOC582782.1.4,,,,,,,,, comp107667_c1_seq1,963,43.5099,0.66302974,1,9,,3.00E-96,Q4V8U5,Anoctamin-10 (Transmembrane protein 16K),Anoctamin-10 (Transmembrane protein 16K),GO:0016021,integral to membrane,PF04547;,,,,,,,,,ANO10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp107667_c1_seq2,720,42.5,0.49585309,0,0,,2.00E-34,Q6PB70,Anoctamin-8 (Transmembrane protein 16H),Anoctamin-8 (Transmembrane protein 16H),GO:0016021; GO:0005622; GO:0005886,integral to membrane; intracellular; plasma membrane,PF04547;,1.00E-88,CHOYP_BRAFLDRAFT_75374.1.1,,,,,,,ANO8_MOUSE,Mus musculus (Mouse),chloride transport [GO:0006821] comp107672_c0_seq1,403,43.4243,0.6076056,5,0,,4.00E-45,Q14642,"Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)","Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)",GO:0007154; GO:0043647; GO:0052659; GO:0052658; GO:0004445; GO:0046856; GO:0005886,"cell communication; inositol phosphate metabolic process; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; inositol-1,4,5-trisphosphate 5-phosphatase activity; inositol-polyphosphate 5-phosphatase activity; phosphatidylinositol dephosphorylation; plasma membrane",PF03372;,5.00E-79,CHOYP_LOC662279.1.1,,,,,,,I5P1_HUMAN,Homo sapiens (Human),inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol dephosphorylation [GO:0046856] comp107676_c0_seq1,557,28.9048,1.21910505,19,91,,,,,,,,,,,2.00E-13,ruditapes_c21640,,,,,,, comp107680_c0_seq1,1343,41.9211,0.74730871,50,62,,6.00E-14,Q5T0B9,Zinc finger protein 362,Zinc finger protein 362,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,4.00E-16,CHOYP_ZN384.1.1,,,,,,,ZN362_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp107687_c0_seq1,295,40.339,1.38838368,17,30,,,,,,,,,4.00E-53,CHOYP_ENPL.3.4,,,,,,,,, comp107688_c1_seq1,292,48.6301,0.40816399,6,21,,9.00E-13,O97394,Protein sidekick,Protein sidekick,GO:0007155; GO:0042675; GO:0005887; GO:0046533; GO:0050931,cell adhesion; compound eye cone cell differentiation; integral to plasma membrane; negative regulation of photoreceptor cell differentiation; pigment cell differentiation,PF00041;PF07679;,,,,,,,,,SDK_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; compound eye cone cell differentiation [GO:0042675]; negative regulation of photoreceptor cell differentiation [GO:0046533]; pigment cell differentiation [GO:0050931] comp107695_c0_seq5,484,42.1488,0.28431973,18,5,,2.00E-69,Q92538,Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),GO:0005086; GO:0048205; GO:0000139; GO:0005795; GO:0005801; GO:0005788; GO:0005739; GO:0019048; GO:0005777; GO:0006892; GO:0032012; GO:0006890; GO:0005802,"ARF guanyl-nucleotide exchange factor activity; COPI coating of Golgi vesicle; Golgi membrane; Golgi stack; cis-Golgi network; endoplasmic reticulum lumen; mitochondrion; modulation by virus of host morphology or physiology; peroxisome; post-Golgi vesicle-mediated transport; regulation of ARF protein signal transduction; retrograde vesicle-mediated transport, Golgi to ER; trans-Golgi network",PF01369;PF12783;,3.00E-83,CHOYP_LOC579332.1.1,,,,,,,GBF1_HUMAN,Homo sapiens (Human),"cell activation involved in immune response [GO:0002263]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]" comp107698_c1_seq1,885,47.4576,0.52622509,35,42,,3.00E-42,Q8NEZ4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,3.00E-15,CHOYP_LOC591084.2.2,,,,,,,MLL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp107703_c0_seq1,595,49.0756,0.49484877,15,16,,,,,,,,,3.00E-84,CHOYP_BRAFLDRAFT_120904.1.1,,,,,,,,, comp107705_c1_seq2,286,45.1049,0.99211089,11,15,,2.00E-16,Q9Y259,Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB),Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB),GO:0005524; GO:0004103; GO:0005829; GO:0004305; GO:0006646,ATP binding; choline kinase activity; cytosol; ethanolamine kinase activity; phosphatidylethanolamine biosynthetic process,,,,,,,,,,CHKB_HUMAN,Homo sapiens (Human),phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646] comp107713_c0_seq1,392,47.449,0.95820895,0,42,,4.00E-10,C6K2K4,Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2),Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2),GO:0016021,integral to membrane,PF00431;PF00057;,,,,,,,,,NETO2_RAT,Rattus norvegicus (Rat),regulation of kainate selective glutamate receptor activity [GO:2000312] comp107720_c0_seq1,258,39.5349,0.30292853,5,5,,2.00E-26,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,,,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp107728_c2_seq1,387,38.5013,1.01723526,13,8,,,,,,,,,8.00E-19,CHOYP_LOC100878929.1.1,3.00E-29,ruditapes_c25355,,,,,,, comp107741_c1_seq4,1391,45.4349,0.37723218,0,0,,1.00E-31,P08169,Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (CD antigen CD222),Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (CD antigen CD222),GO:0009986; GO:0030139; GO:0001948; GO:0016021; GO:0005765; GO:0051219; GO:0005215,cell surface; endocytic vesicle; glycoprotein binding; integral to membrane; lysosomal membrane; phosphoprotein binding; transporter activity,PF00878;PF00040;,,,,,,,,,MPRI_BOVIN,Bos taurus (Bovine), comp107751_c0_seq2,935,43.1016,0.48435322,21,15,,5.00E-17,Q96C55,Zinc finger protein 524,Zinc finger protein 524,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,2.00E-18,CHOYP_DGRI_GH21290.1.1,,,,,,,ZN524_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp107760_c0_seq2,534,46.4419,0.59339935,2,29,,9.00E-69,Q5R9W5,WW domain-containing oxidoreductase (EC 1.1.1.-),WW domain-containing oxidoreductase (EC 1.1.1.-),GO:0016055; GO:0006915; GO:0005737; GO:0005739; GO:0030178; GO:0005634; GO:0016491,Wnt receptor signaling pathway; apoptotic process; cytoplasm; mitochondrion; negative regulation of Wnt receptor signaling pathway; nucleus; oxidoreductase activity,PF00106;PF00397;,3.00E-45,CHOYP_WWOX.1.1,,,,,,,WWOX_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),apoptotic process [GO:0006915]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp107771_c0_seq1,311,42.1222,0.14586406,3,32,,7.00E-07,P56500,Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8),Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8),GO:0007568; GO:0034198; GO:0071333; GO:0032869; GO:0007565; GO:0016021; GO:0097421; GO:0005743; GO:0006839; GO:0005739; GO:0043066; GO:0061179; GO:0010942; GO:0070542; GO:0001666; GO:0000303,aging; cellular response to amino acid starvation; cellular response to glucose stimulus; cellular response to insulin stimulus; female pregnancy; integral to membrane; liver regeneration; mitochondrial inner membrane; mitochondrial transport; mitochondrion; negative regulation of apoptotic process; negative regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of cell death; response to fatty acid; response to hypoxia; response to superoxide,PF00153;,7.00E-12,CHOYP_BRAFLDRAFT_287708.1.1,,,,,,,UCP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose stimulus [GO:0071333]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; female pregnancy [GO:0007565]; liver regeneration [GO:0097421]; mitochondrial transport [GO:0006839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; positive regulation of cell death [GO:0010942]; regulation of mitochondrial membrane potential [GO:0051881]; response to fatty acid [GO:0070542]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to superoxide [GO:0000303]; translation [GO:0006412] comp107771_c1_seq1,332,47.2892,0.34555831,3,31,,1.00E-30,Q5NVC1,Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19),Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19),GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,,,,,,,,,TPC_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),transmembrane transport [GO:0055085] comp107782_c0_seq1,1226,42.6591,0.45255408,9,41,,6.00E-102,Q19905,UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Squashed vulva protein 4),UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Squashed vulva protein 4),GO:0051287; GO:0003979; GO:0006065; GO:0005737; GO:0009792; GO:0006024; GO:0002009; GO:0018991; GO:0040025,NAD binding; UDP-glucose 6-dehydrogenase activity; UDP-glucuronate biosynthetic process; cytoplasm; embryo development ending in birth or egg hatching; glycosaminoglycan biosynthetic process; morphogenesis of an epithelium; oviposition; vulval development,PF00984;PF03720;PF03721;,7.00E-159,CHOYP_BRAFLDRAFT_126506.1.1,,,,,,,UGDH_CAEEL,Caenorhabditis elegans,carbohydrate metabolic process [GO:0005975]; embryo development ending in birth or egg hatching [GO:0009792]; glycosaminoglycan biosynthetic process [GO:0006024]; morphogenesis of an epithelium [GO:0002009]; oviposition [GO:0018991]; reproduction [GO:0000003]; UDP-glucuronate biosynthetic process [GO:0006065]; vulval development [GO:0040025] comp107782_c0_seq3,925,44.5405,0.42420785,0,0,,2.00E-113,O02373,UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Protein sugarless) (Protein suppenkasper),UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Protein sugarless) (Protein suppenkasper),GO:0051287; GO:0003979; GO:0006065; GO:0016055; GO:0030206; GO:0007427; GO:0008543; GO:0007507; GO:0015014; GO:0007476; GO:0002121; GO:0007509; GO:0016319; GO:0042048; GO:0007428; GO:0007367; GO:0007224,"NAD binding; UDP-glucose 6-dehydrogenase activity; UDP-glucuronate biosynthetic process; Wnt receptor signaling pathway; chondroitin sulfate biosynthetic process; epithelial cell migration, open tracheal system; fibroblast growth factor receptor signaling pathway; heart development; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; mesoderm migration involved in gastrulation; mushroom body development; olfactory behavior; primary branching, open tracheal system; segment polarity determination; smoothened signaling pathway",PF00984;PF03720;PF03721;,,,,,,,,,UGDH_DROME,Drosophila melanogaster (Fruit fly),"carbohydrate metabolic process [GO:0005975]; cell surface receptor signaling pathway [GO:0007166]; chondroitin sulfate biosynthetic process [GO:0030206]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; mesoderm migration involved in gastrulation [GO:0007509]; mushroom body development [GO:0016319]; olfactory behavior [GO:0042048]; primary branching, open tracheal system [GO:0007428]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; UDP-glucuronate biosynthetic process [GO:0006065]; Wnt signaling pathway [GO:0016055]" comp107785_c0_seq1,356,38.4831,1.31311381,36,19,,6.00E-10,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp107791_c1_seq1,232,48.7069,0.21940144,3,4,,7.00E-06,Q6AYM1,Uncharacterized protein C5orf34 homolog,Uncharacterized protein C5orf34 homolog,,,PF15016;PF15025;,,,,,,,,,CE034_RAT,Rattus norvegicus (Rat), comp107793_c0_seq1,589,43.2937,0.47345815,19,25,,3.00E-31,Q9R1X5,Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP),Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP),GO:0005524; GO:0006200; GO:0042626; GO:0016021,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane",PF00664;PF00005;,8.00E-15,CHOYP_MRP5.3.3,,,,,,,MRP5_MOUSE,Mus musculus (Mouse), comp107818_c0_seq1,414,37.6812,0.21754452,12,77,,2.00E-48,Q86SZ2,Trafficking protein particle complex subunit 6B,Trafficking protein particle complex subunit 6B,GO:0005794; GO:0005783; GO:0016192,Golgi apparatus; endoplasmic reticulum; vesicle-mediated transport,PF04051;,5.00E-47,CHOYP_LOC594183.1.1,,,,,,,TPC6B_HUMAN,Homo sapiens (Human),COPII vesicle coating [GO:0048208] comp107831_c1_seq1,387,37.7261,0.5263601,8,3,,3.00E-53,Q3T000,Synaptobrevin homolog YKT6 (EC 2.3.1.-),Synaptobrevin homolog YKT6 (EC 2.3.1.-),GO:0006888; GO:0000139; GO:0030659; GO:0005829; GO:0005783; GO:0005768; GO:0005887; GO:0005739; GO:0015031; GO:0019706; GO:0042147; GO:0006904; GO:0006903,"ER to Golgi vesicle-mediated transport; Golgi membrane; cytoplasmic vesicle membrane; cytosol; endoplasmic reticulum; endosome; integral to plasma membrane; mitochondrion; protein transport; protein-cysteine S-palmitoyltransferase activity; retrograde transport, endosome to Golgi; vesicle docking involved in exocytosis; vesicle targeting",PF13774;PF00957;,,,,,,,,,YKT6_BOVIN,Bos taurus (Bovine),"ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903]" comp107833_c0_seq1,832,34.7356,0.8301786,53,18,,5.00E-31,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp107842_c0_seq1,285,44.5614,0.07428663,8,0,,1.00E-08,Q9BX66,Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),GO:0005070; GO:0003779; GO:0005813; GO:0005829; GO:0005925; GO:0048041; GO:0015758; GO:0005158; GO:0008286; GO:0045121; GO:0006936; GO:0016363; GO:0005634; GO:0005886; GO:0090004; GO:0046326; GO:0045725; GO:0046889; GO:0001725; GO:0043149; GO:0005915,SH3/SH2 adaptor activity; actin binding; centrosome; cytosol; focal adhesion; focal adhesion assembly; glucose transport; insulin receptor binding; insulin receptor signaling pathway; membrane raft; muscle contraction; nuclear matrix; nucleus; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; stress fiber; stress fiber assembly; zonula adherens,PF00018;PF07653;PF14604;PF02208;,,,,,,,,,SRBS1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149] comp107842_c1_seq1,389,48.8432,0.55714654,18,15,,2.00E-18,Q91X43,SH3 domain-containing protein 19 (Kryn),SH3 domain-containing protein 19 (Kryn),GO:0005737; GO:0007010; GO:0022604,cytoplasm; cytoskeleton organization; regulation of cell morphogenesis,PF00018;PF07653;PF14604;,,,,,,,,,SH319_MOUSE,Mus musculus (Mouse),cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604] comp107847_c0_seq1,345,45.2174,0.41134856,14,6,,2.00E-37,O75096,Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),GO:0016055; GO:0005509; GO:0030154; GO:0009953; GO:0042733; GO:0006897; GO:0030198; GO:0001942; GO:0016021; GO:0001822; GO:0090090; GO:0030279; GO:0042475; GO:0005886; GO:0009954; GO:0043113; GO:0001932; GO:0051124,Wnt receptor signaling pathway; calcium ion binding; cell differentiation; dorsal/ventral pattern formation; embryonic digit morphogenesis; endocytosis; extracellular matrix organization; hair follicle development; integral to membrane; kidney development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of ossification; odontogenesis of dentin-containing tooth; plasma membrane; proximal/distal pattern formation; receptor clustering; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF12662;PF00057;PF00058;,,,,,,,,,LRP4_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] comp107848_c0_seq1,232,45.2586,0.59832366,3,9,,4.00E-17,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,3.00E-22,CHOYP_LOC100708199.6.6,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp107848_c1_seq1,205,42.439,0.32699191,0,7,,5.00E-07,Q9UR07,Transposon Tf2-11 polyprotein (Retrotransposable element Tf2 155 kDa protein),Transposon Tf2-11 polyprotein (Retrotransposable element Tf2 155 kDa protein),GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005634; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; nucleus; proteolysis,PF12382;PF00665;PF00078;,,,,,,,,,RTF23_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp107869_c0_seq1,408,34.0686,0.42711201,54,18,,1.00E-06,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp107875_c0_seq1,521,41.8426,0.66042753,29,6,,2.00E-55,Q8BQM9,Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09497;PF12145;PF12144;,7.00E-28,CHOYP_MD12L.1.1,,,,,,,MD12L_MOUSE,Mus musculus (Mouse), comp107894_c0_seq1,891,38.4961,0.85810594,2,62,,1.00E-30,Q4V8D1,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_RAT,Rattus norvegicus (Rat), comp107900_c1_seq1,230,39.1304,0.34239778,3,7,,9.00E-30,Q8BTQ0,Polycomb group RING finger protein 3 (RING finger protein 3A),Polycomb group RING finger protein 3 (RING finger protein 3A),GO:0031519; GO:0006355; GO:0006351; GO:0008270,"PcG protein complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF16207;,8.00E-16,CHOYP_LOC100874646.1.1,,,,,,,PCGF3_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp107903_c1_seq1,382,43.7173,0.60917132,11,37,,3.00E-11,P41696,Asparagine-rich zinc finger protein AZF1,Asparagine-rich zinc finger protein AZF1,GO:0000978; GO:0001077; GO:0071322; GO:0005829; GO:0046872; GO:0005634; GO:0060237,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to carbohydrate stimulus; cytosol; metal ion binding; nucleus; regulation of fungal-type cell wall organization,PF13912;,,,,,,,,,AZF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp107905_c0_seq1,558,35.8423,0.6332015,0,0,,1.00E-17,Q5U316,Ras-related protein Rab-35,Ras-related protein Rab-35,GO:0019003; GO:0005525; GO:0031253; GO:1990090; GO:0045334; GO:0005905; GO:0000910; GO:0016197; GO:0010008; GO:0045171; GO:0042470; GO:0005739; GO:0031175; GO:0005546; GO:0036010; GO:0015031; GO:0007264,"GDP binding; GTP binding; cell projection membrane; cellular response to nerve growth factor stimulus; clathrin-coated endocytic vesicle; coated pit; cytokinesis; endosomal transport; endosome membrane; intercellular bridge; melanosome; mitochondrion; neuron projection development; phosphatidylinositol-4,5-bisphosphate binding; protein localization to endosome; protein transport; small GTPase mediated signal transduction",PF00071;,,,,,,,,,RAB35_RAT,Rattus norvegicus (Rat),antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp107905_c0_seq2,727,37.8267,0.79982573,5,40,,2.00E-58,Q5U316,Ras-related protein Rab-35,Ras-related protein Rab-35,GO:0019003; GO:0005525; GO:0031253; GO:1990090; GO:0045334; GO:0005905; GO:0000910; GO:0016197; GO:0010008; GO:0045171; GO:0042470; GO:0005739; GO:0031175; GO:0005546; GO:0036010; GO:0015031; GO:0007264,"GDP binding; GTP binding; cell projection membrane; cellular response to nerve growth factor stimulus; clathrin-coated endocytic vesicle; coated pit; cytokinesis; endosomal transport; endosome membrane; intercellular bridge; melanosome; mitochondrion; neuron projection development; phosphatidylinositol-4,5-bisphosphate binding; protein localization to endosome; protein transport; small GTPase mediated signal transduction",PF00071;,3.00E-85,CHOYP_RAB35.1.1,,,,,,,RAB35_RAT,Rattus norvegicus (Rat),antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp107927_c0_seq2,764,42.9319,0.35011502,26,14,,1.00E-91,Q0P651,Uncharacterized protein C4orf29,Protein ABHD18 (Alpha/beta hydrolase domain-containing protein 18) (Abhydrolase domain-containing protein 18),GO:0005576,extracellular region,PF09752;,,,,,,,,,CD029_HUMAN,Homo sapiens (Human), comp107938_c0_seq1,307,43.6482,1.04055158,0,20,,7.00E-07,P13611,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),GO:0005796; GO:0005509; GO:0030246; GO:0005975; GO:0007155; GO:0008037; GO:0030206; GO:0030207; GO:0030208; GO:0030198; GO:0005615; GO:0008347; GO:0007507; GO:0005540; GO:0043202; GO:0007275; GO:0005578,Golgi lumen; calcium ion binding; carbohydrate binding; carbohydrate metabolic process; cell adhesion; cell recognition; chondroitin sulfate biosynthetic process; chondroitin sulfate catabolic process; dermatan sulfate biosynthetic process; extracellular matrix organization; extracellular space; glial cell migration; heart development; hyaluronic acid binding; lysosomal lumen; multicellular organismal development; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell recognition [GO:0008037]; central nervous system development [GO:0007417]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate biosynthetic process [GO:0030208]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; glycosaminoglycan metabolic process [GO:0030203]; multicellular organism development [GO:0007275]; osteoblast differentiation [GO:0001649]; skeletal system development [GO:0001501] comp107938_c0_seq2,221,42.9864,0.80218445,0,0,,8.00E-09,Q9ULI3,Protein HEG homolog 1,Protein HEG homolog 1,GO:0005509; GO:0003209; GO:0005911; GO:0045216; GO:0001886; GO:0009897; GO:0005576; GO:0001701; GO:0016021; GO:0030324; GO:0003017; GO:0001945; GO:0035264; GO:0060039; GO:0009791; GO:0050878; GO:0001570; GO:0048845; GO:0003281,calcium ion binding; cardiac atrium morphogenesis; cell-cell junction; cell-cell junction organization; endothelial cell morphogenesis; external side of plasma membrane; extracellular region; in utero embryonic development; integral to membrane; lung development; lymph circulation; lymph vessel development; multicellular organism growth; pericardium development; post-embryonic development; regulation of body fluid levels; vasculogenesis; venous blood vessel morphogenesis; ventricular septum development,PF00008;PF07645;,,,,,,,,,HEG1_HUMAN,Homo sapiens (Human),cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp107941_c0_seq1,890,36.8539,0.69632777,20,71,,1.00E-06,Q8N884,Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (Mab-21 domain-containing protein 1),Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1),GO:0005524; GO:0003677; GO:0005525; GO:0002218; GO:0071360; GO:0009190; GO:0061501; GO:0005829; GO:0051607; GO:0045087; GO:0046872; GO:0002230; GO:0032481,ATP binding; DNA binding; GTP binding; activation of innate immune response; cellular response to exogenous dsRNA; cyclic nucleotide biosynthetic process; cyclic-GMP-AMP synthase activity; cytosol; defense response to virus; innate immune response; metal ion binding; positive regulation of defense response to virus by host; positive regulation of type I interferon production,PF03281;,,,,,,,,,M21D1_HUMAN,Homo sapiens (Human),activation of innate immune response [GO:0002218]; cellular response to exogenous dsRNA [GO:0071360]; cyclic nucleotide biosynthetic process [GO:0009190]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481] comp107980_c0_seq1,656,42.378,0.20454593,16,15,,7.00E-22,Q8K2Y9,Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3),Cerebral cavernous malformations protein 2 homolog (Malcavernin) (Osmosensing scaffold for MEKK3),GO:0060837; GO:0045216; GO:0005737; GO:0001885; GO:0061154; GO:0001701; GO:0048839; GO:0035264; GO:0060039; GO:0043234; GO:0001570; GO:0048845,blood vessel endothelial cell differentiation; cell-cell junction organization; cytoplasm; endothelial cell development; endothelial tube morphogenesis; in utero embryonic development; inner ear development; multicellular organism growth; pericardium development; protein complex; vasculogenesis; venous blood vessel morphogenesis,PF16545;,,,,,,,,,CCM2_MOUSE,Mus musculus (Mouse),blood vessel development [GO:0001568]; blood vessel endothelial cell differentiation [GO:0060837]; cell-cell junction organization [GO:0045216]; endothelial cell development [GO:0001885]; endothelial tube morphogenesis [GO:0061154]; heart development [GO:0007507]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845] comp107980_c0_seq2,216,38.8889,0.25529959,1,0,,3.00E-08,Q9BSQ5,Malcavernin (Cerebral cavernous malformations 2 protein),Cerebral cavernous malformations 2 protein (Malcavernin),GO:0060837; GO:0045216; GO:0005737; GO:0001885; GO:0061154; GO:0001701; GO:0048839; GO:0007229; GO:0035264; GO:0060039; GO:0043234; GO:0051403; GO:0001570; GO:0048845,blood vessel endothelial cell differentiation; cell-cell junction organization; cytoplasm; endothelial cell development; endothelial tube morphogenesis; in utero embryonic development; inner ear development; integrin-mediated signaling pathway; multicellular organism growth; pericardium development; protein complex; stress-activated MAPK cascade; vasculogenesis; venous blood vessel morphogenesis,PF16545;,,,,,,,,,CCM2_HUMAN,Homo sapiens (Human),blood vessel endothelial cell differentiation [GO:0060837]; cell-cell junction organization [GO:0045216]; endothelial cell development [GO:0001885]; endothelial tube morphogenesis [GO:0061154]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; stress-activated MAPK cascade [GO:0051403]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845] comp107988_c0_seq1,202,43.0693,1.23920906,5,0,,,,,,,,,7.00E-16,CHOYP_BRAFLDRAFT_68915.4.7,7.00E-20,ruditapes_c4565,,,,,,, comp108002_c0_seq2,977,38.2805,0.39520896,11,34,,4.00E-97,Q6NYU7,Uracil phosphoribosyltransferase homolog,Uracil phosphoribosyltransferase homolog,GO:0005737; GO:0005634,cytoplasm; nucleus,PF14681;,2.00E-69,CHOYP_LOC100161158.1.1,,,,,,,UPP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp108021_c0_seq1,420,34.5238,0.56283742,11,80,,2.00E-18,Q757W2,Chromatin modification-related protein YNG2 (ING1 homolog 2),Chromatin modification-related protein YNG2 (ING1 homolog 2),GO:0006281; GO:0032777; GO:0004402; GO:0007126; GO:0008270,DNA repair; Piccolo NuA4 histone acetyltransferase complex; histone acetyltransferase activity; meiosis; zinc ion binding,PF12998;,,,,,,,,,YNG2_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter [GO:1900404]; regulation of histone H4 acetylation involved in response to DNA damage stimulus [GO:2000873] comp108023_c0_seq1,208,54.3269,1.17859867,0,4,,3.00E-12,P64803,"Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase)",,GO:0005524; GO:0008817; GO:0009236; GO:0005737; GO:0006779,"ATP binding; cob(I)yrinic acid a,c-diamide adenosyltransferase activity; cobalamin biosynthetic process; cytoplasm; porphyrin-containing compound biosynthetic process",,,,,,,,,,PDUO_MYCTU,, comp108027_c0_seq4,445,41.3483,0.37043376,0,0,,,,,,,,,6.00E-21,CHOYP_contig_013878,,,,,,,,, comp108034_c0_seq1,294,41.8367,0.48493712,7,7,,2.00E-18,Q3TLI0,Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),GO:0005794; GO:0016192,Golgi apparatus; vesicle-mediated transport,PF12584;,,,,,,,,,TPC10_MOUSE,Mus musculus (Mouse),early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891] comp108040_c0_seq1,656,42.2256,0.27590615,20,63,,2.00E-48,Q9UPM8,AP-4 complex subunit epsilon-1 (AP-4 adapter complex subunit epsilon) (Adapter-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin),AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin),GO:0005794; GO:0006886; GO:0030117; GO:0016192,Golgi apparatus; intracellular protein transport; membrane coat; vesicle-mediated transport,PF01602;PF14807;,,,,,,,,,AP4E1_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp108045_c0_seq1,672,44.3452,0.64711682,33,21,,6.00E-95,Q6AX33,Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1),Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1),GO:0005524; GO:0000287; GO:0004674,ATP binding; magnesium ion binding; protein serine/threonine kinase activity,PF08926;PF00595;PF00069;,7.00E-92,CHOYP_MAST4.1.1,,,,,,,MAST3_XENLA,Xenopus laevis (African clawed frog), comp108045_c1_seq1,415,46.0241,0.64000372,14,14,,2.00E-20,P25323,Myosin light chain kinase A (MLCK-A) (EC 2.7.11.18),Myosin light chain kinase A (MLCK-A) (EC 2.7.11.18),GO:0005524; GO:0030898; GO:0019933; GO:0019934; GO:0005737; GO:0000281; GO:0004687; GO:0046777; GO:0050920,ATP binding; actin-dependent ATPase activity; cAMP-mediated signaling; cGMP-mediated signaling; cytoplasm; mitotic cytokinesis; myosin light chain kinase activity; protein autophosphorylation; regulation of chemotaxis,PF00069;,,,,,,,,,MYLKA_DICDI,Dictyostelium discoideum (Slime mold),cAMP-mediated signaling [GO:0019933]; cGMP-mediated signaling [GO:0019934]; mitotic cytokinesis [GO:0000281]; protein autophosphorylation [GO:0046777]; regulation of chemotaxis [GO:0050920] comp108053_c0_seq1,213,64.3192,1.23306175,0,18,,5.00E-10,Q74EE6,Uncharacterized transporter GSU1016,Uncharacterized transporter GSU1016,GO:0008324; GO:0016021; GO:0005886; GO:0006813,cation transmembrane transporter activity; integral to membrane; plasma membrane; potassium ion transport,PF06826;PF02080;,,,,,,,,,Y1016_GEOSL,Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA),potassium ion transport [GO:0006813] comp108053_c1_seq1,276,62.3188,1.08672963,0,14,,4.00E-52,Q6A666,Uncharacterized transporter PPA2034,Uncharacterized transporter PPA2034,GO:0008324; GO:0016021; GO:0005886; GO:0006813,cation transmembrane transporter activity; integral to membrane; plasma membrane; potassium ion transport,PF06826;PF02080;,,,,,,,,,Y2034_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),potassium ion transport [GO:0006813] comp108064_c0_seq1,403,41.9355,0.23771844,12,48,,3.00E-16,Q5RDE9,Leptin receptor overlapping transcript-like 1,Leptin receptor overlapping transcript-like 1,GO:0016021,integral to membrane,PF04133;,,,,,,,,,LERL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp108074_c0_seq1,262,34.3511,0.65456404,3,4,,1.00E-09,Q5ZLC8,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_CHICK,Gallus gallus (Chicken), comp108074_c0_seq2,281,32.3843,0.40870083,3,21,,1.00E-12,Q5UP11,Putative ankyrin repeat protein R848,Putative ankyrin repeat protein R848,,,PF12796;,,,,,,,,,YR848_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp108090_c0_seq2,599,48.414,0.34377483,1,47,,3.00E-55,Q96QU8,Exportin-6 (Exp6) (Ran-binding protein 20),Exportin-6 (Exp6) (Ran-binding protein 20),GO:0005737; GO:0005730; GO:0005886; GO:0006611; GO:0008565,cytoplasm; nucleolus; plasma membrane; protein export from nucleus; protein transporter activity,PF03810;PF08389;,2.00E-40,CHOYP_XPO6.1.1,,,,,,,XPO6_HUMAN,Homo sapiens (Human),protein export from nucleus [GO:0006611] comp108091_c0_seq1,840,46.3095,0.82254941,13,235,,1.00E-10,B0UZC8,von Willebrand factor C domain-containing protein 2-like,von Willebrand factor C domain-containing protein 2-like,GO:0030054; GO:0005576; GO:0007399; GO:0045202,cell junction; extracellular region; nervous system development; synapse,PF00093;,,,,,,,,,VWC2L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nervous system development [GO:0007399] comp108107_c0_seq1,940,39.7872,0.83959915,0,247,,8.00E-10,O00339,Matrilin-2,Matrilin-2,GO:0007411; GO:0005604; GO:0005509; GO:0031104; GO:0008347; GO:0001764; GO:0005578; GO:0048678,axon guidance; basement membrane; calcium ion binding; dendrite regeneration; glial cell migration; neuron migration; proteinaceous extracellular matrix; response to axon injury,PF12662;PF07645;PF10393;PF00092;,,,,,,,,,MATN2_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; response to axon injury [GO:0048678] comp108117_c0_seq2,523,37.4761,0.38192559,0,0,,,,,,,,,,,1.00E-10,ruditapes2_c2711,,,,,,, comp108132_c0_seq1,271,36.5314,0.93875308,0,27,,4.00E-13,Q3TGW2,Endonuclease/exonuclease/phosphatase family domain-containing protein 1,Endonuclease/exonuclease/phosphatase family domain-containing protein 1,GO:0003677; GO:0006281,DNA binding; DNA repair,PF03372;,,,,,,,,,EEPD1_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281] comp108133_c1_seq1,542,40.4059,0.64874773,27,16,,8.00E-33,Q6GQN7,Rab9 effector protein with kelch motifs,Rab9 effector protein with kelch motifs,,,PF07646;,2.00E-35,CHOYP_LOC100373945.1.1,,,,,,,RABEK_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp108133_c2_seq1,289,44.9827,0.62306786,9,0,,5.00E-08,Q8RWD9,Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5),Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5),GO:0005829; GO:0000062; GO:0008289; GO:0006869; GO:0009416,cytosol; fatty-acyl-CoA binding; lipid binding; lipid transport; response to light stimulus,PF00887;,,,,,,,,,ACBP5_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869]; response to hypoxia [GO:0001666]; response to light stimulus [GO:0009416] comp108141_c0_seq1,238,64.2857,1.06405988,0,14,,2.00E-31,A1SCM2,DNA gyrase subunit A (EC 5.99.1.3),DNA gyrase subunit A (EC 5.99.1.3),GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0006261; GO:0005694; GO:0005737,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; DNA-dependent DNA replication; chromosome; cytoplasm,PF03989;PF00521;,,,,,,,,,GYRA_NOCSJ,Nocardioides sp. (strain ATCC BAA-499 / JS614),DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265] comp108145_c0_seq1,292,41.4384,1.0288042,21,0,,,,,,,,,2.00E-11,CHOYP_contig_024470,,,,,,,,, comp108147_c0_seq1,218,40.367,0.23612357,7,5,,,,,,,,,4.00E-19,CHOYP_NEMVEDRAFT_V1G237545.1.1,,,,,,,,, comp108147_c1_seq1,231,42.8571,0.59488294,2,6,,2.00E-06,Q4KM33,Pleckstrin,Pleckstrin,GO:0031532; GO:0030866; GO:0005737; GO:0002244; GO:0007229; GO:0045744; GO:0010920; GO:0046488; GO:0043325; GO:0030845; GO:0070527; GO:0032233; GO:0030836; GO:0010925; GO:0033625; GO:0010572; GO:0070528; GO:0070560; GO:0060305; GO:0032587; GO:0031529; GO:0070493; GO:0006904,"actin cytoskeleton reorganization; cortical actin cytoskeleton organization; cytoplasm; hematopoietic progenitor cell differentiation; integrin-mediated signaling pathway; negative regulation of G-protein coupled receptor protein signaling pathway; negative regulation of inositol phosphate biosynthetic process; phosphatidylinositol metabolic process; phosphatidylinositol-3,4-bisphosphate binding; phospholipase C-inhibiting G-protein coupled receptor signaling pathway; platelet aggregation; positive regulation of actin filament bundle assembly; positive regulation of actin filament depolymerization; positive regulation of inositol-polyphosphate 5-phosphatase activity; positive regulation of integrin activation; positive regulation of platelet activation; protein kinase C signaling cascade; protein secretion by platelet; regulation of cell diameter; ruffle membrane; ruffle organization; thrombin receptor signaling pathway; vesicle docking involved in exocytosis",PF00610;PF00169;,,,,,,,,,PLEK_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G-protein coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904] comp108147_c2_seq1,268,39.5522,0.30022739,9,6,,2.00E-06,Q9NYT0,Pleckstrin-2,Pleckstrin-2,GO:0030036; GO:0005737; GO:0005856; GO:0035556; GO:0031258; GO:0005543,actin cytoskeleton organization; cytoplasm; cytoskeleton; intracellular signal transduction; lamellipodium membrane; phospholipid binding,PF00610;PF00169;,,,,,,,,,PLEK2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; intracellular signal transduction [GO:0035556] comp108149_c0_seq2,360,41.3889,0.3997816,6,17,,5.00E-30,O75943,Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog),Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog),GO:0005524; GO:0000077; GO:0006281; GO:0006260; GO:0000076; GO:0007093; GO:0008156; GO:0005654; GO:0017111; GO:0042325,ATP binding; DNA damage checkpoint; DNA repair; DNA replication; DNA replication checkpoint; mitotic cell cycle checkpoint; negative regulation of DNA replication; nucleoplasm; nucleoside-triphosphatase activity; regulation of phosphorylation,,2.00E-26,CHOYP_LOC582037.1.1,,,,,,,RAD17_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication checkpoint [GO:0000076]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of DNA replication [GO:0008156]; regulation of phosphorylation [GO:0042325]; regulation of signal transduction by p53 class mediator [GO:1901796] comp108149_c0_seq3,724,42.5414,0.46355587,32,35,,1.00E-13,Q9MBA3,Cell cycle checkpoint protein RAD17 (AtRAD17) (Radiation-sensitive protein 17),Cell cycle checkpoint protein RAD17 (AtRAD17) (Radiation-sensitive protein 17),GO:0005524; GO:0006281; GO:0007049; GO:0005634; GO:0006282,ATP binding; DNA repair; cell cycle; nucleus; regulation of DNA repair,,,,,,,,,,RAD17_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell cycle [GO:0007049]; DNA repair [GO:0006281]; regulation of DNA repair [GO:0006282] comp108160_c0_seq2,1029,43.9261,0.5649258,40,29,,5.00E-108,O75976,Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180),Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180),GO:0016021; GO:0016020; GO:0004181; GO:0006508; GO:0004185; GO:0008270,integral to membrane; membrane; metallocarboxypeptidase activity; proteolysis; serine-type carboxypeptidase activity; zinc ion binding,PF00246;,2.00E-56,CHOYP_LOC100533325.1.1,,,,,,,CBPD_HUMAN,Homo sapiens (Human),peptide metabolic process [GO:0006518]; protein processing [GO:0016485] comp108160_c1_seq1,394,36.5482,0.53430296,8,15,,8.00E-20,P29068,Carboxypeptidase T (EC 3.4.17.18),Carboxypeptidase T (EC 3.4.17.18),GO:0004181; GO:0006508; GO:0008270,metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,,,,,,,,,CBPT_THEVU,Thermoactinomyces vulgaris, comp108168_c2_seq1,326,34.3558,0.43383493,4,9,,5.00E-10,Q8NEP3,"Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)","Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)",GO:0035085; GO:0071907; GO:0071910; GO:0035469; GO:0045502; GO:0060287; GO:0001947; GO:0036159; GO:0060972; GO:0030324; GO:0044458; GO:0005634; GO:0036158; GO:0005886; GO:0003356; GO:0000922,cilium axoneme; determination of digestive tract left/right asymmetry; determination of liver left/right asymmetry; determination of pancreatic left/right asymmetry; dynein binding; epithelial cilium movement involved in determination of left/right asymmetry; heart looping; inner dynein arm assembly; left/right pattern formation; lung development; motile cilium assembly; nucleus; outer dynein arm assembly; plasma membrane; regulation of cilium beat frequency; spindle pole,,,,,,,,,,DAAF1_HUMAN,Homo sapiens (Human),axonemal dynein complex assembly [GO:0070286]; cilium morphogenesis [GO:0060271]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; left/right pattern formation [GO:0060972]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356] comp108173_c2_seq1,331,48.3384,0.62602708,8,15,,7.00E-11,Q61329,Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3),Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3),GO:0005739; GO:0007517; GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"mitochondrion; muscle organ development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;,6.00E-26,CHOYP_LOC100877335.1.1,,,,,,,ZFHX3_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; muscle organ development [GO:0007517]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of locomotor rhythm [GO:1904059]; response to transforming growth factor beta [GO:0071559]; transcription, DNA-templated [GO:0006351]" comp108176_c0_seq1,299,39.7993,0.63063768,2,12,,2.00E-08,Q17551,E3 ubiquitin-protein ligase rpm-1 (EC 6.3.2.-) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3),E3 ubiquitin-protein ligase rpm-1 (EC 6.3.2.-) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3),GO:0030424; GO:0010171; GO:0040011; GO:0043409; GO:0031594; GO:0005634; GO:0018991; GO:0036062; GO:0031647; GO:0050807; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; body morphogenesis; locomotion; negative regulation of MAPK cascade; neuromuscular junction; nucleus; oviposition; presynaptic periactive zone; regulation of protein stability; regulation of synapse organization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF08005;PF00415;PF00643;PF13639;,,,,,,,,,RPM1_CAEEL,Caenorhabditis elegans,"body morphogenesis [GO:0010171]; locomotion [GO:0040011]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of axon regeneration [GO:0048681]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of MAPK cascade [GO:0043409]; oviposition [GO:0018991]; positive regulation of synapse assembly [GO:0051965]; regulation of protein stability [GO:0031647]; regulation of synapse organization [GO:0050807]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108184_c0_seq1,603,34.66,0.49807724,15,39,,1.00E-15,O42409,Zinc finger protein Gfi-1b (Growth factor-independent protein 1B),Zinc finger protein Gfi-1b (Growth factor-independent protein 1B),GO:0003677; GO:0016568; GO:0007275; GO:0016363; GO:0006355; GO:0005667; GO:0006351; GO:0008270,"DNA binding; chromatin modification; multicellular organismal development; nuclear matrix; regulation of transcription, DNA-dependent; transcription factor complex; transcription, DNA-dependent; zinc ion binding",PF00096;,,,,,,,,,GFI1B_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108184_c2_seq1,515,38.4466,0.90424009,11,35,,9.00E-20,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp108189_c0_seq1,1034,34.913,0.58084484,91,39,,2.00E-07,Q08AY9,Protein FAM89A,Protein FAM89A,,,,,,,,,,,,FA89A_XENLA,Xenopus laevis (African clawed frog), comp108202_c0_seq1,248,48.7903,0.82315388,5,14,,1.00E-23,P20483,M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string),M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string),GO:0000086; GO:0007030; GO:0051301; GO:0008283; GO:0007099; GO:0005694; GO:0007369; GO:0046331; GO:0007498; GO:0007067; GO:0045792; GO:0045930; GO:0005634; GO:0007424; GO:0007422; GO:0008284; GO:0045977; GO:0004725; GO:0008138; GO:0060305,"G2/M transition of mitotic cell cycle; Golgi organization; cell division; cell proliferation; centriole replication; chromosome; gastrulation; lateral inhibition; mesoderm development; mitosis; negative regulation of cell size; negative regulation of mitotic cell cycle; nucleus; open tracheal system development; peripheral nervous system development; positive regulation of cell proliferation; positive regulation of mitotic cell cycle, embryonic; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of cell diameter",PF00581;,,,,,,,,,MPIP_DROME,Drosophila melanogaster (Fruit fly),"cell division [GO:0051301]; cell proliferation [GO:0008283]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; histoblast morphogenesis [GO:0007488]; lateral inhibition [GO:0046331]; mesoderm development [GO:0007498]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; negative regulation of cell size [GO:0045792]; negative regulation of mitotic cell cycle [GO:0045930]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cell cycle, embryonic [GO:0045977]; protein dephosphorylation [GO:0006470]; regulation of cell diameter [GO:0060305]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]" comp108204_c0_seq1,529,44.0454,0.27339818,20,14,,6.00E-06,Q8BX70,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp108215_c0_seq1,604,45.5298,0.48184267,0,0,,3.00E-06,O88277,Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),GO:0005509; GO:0005913; GO:0010631; GO:0007156; GO:0016021; GO:0005634; GO:0005886,calcium ion binding; cell-cell adherens junction; epithelial cell migration; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT2_RAT,Rattus norvegicus (Rat),epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp108215_c0_seq2,984,45.935,0.46316662,23,0,,9.00E-14,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp108216_c0_seq1,906,36.4238,0.27049427,15,99,,1.00E-06,Q535K8,GON-4-like protein (GON-4 homolog) (Protein GON4),GON-4-like protein (GON-4 homolog) (Protein GON4),GO:0003677; GO:0003682; GO:0005634; GO:0006355,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent",PF02671;,,,,,,,,,GON4L_RAT,Rattus norvegicus (Rat),"B cell differentiation [GO:0030183]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp108228_c0_seq1,477,46.7505,0.31150349,132,4,,2.00E-40,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-75,CHOYP_BRAFLDRAFT_108792.4.5,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp108232_c0_seq1,483,42.236,0.47068178,29,4,,7.00E-18,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,1.00E-12,CHOYP_SACS.12.17,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp108237_c1_seq1,667,36.5817,0.82792998,34,84,,1.00E-12,Q16932,Syntaxin,Syntaxin,GO:0016021; GO:0006886; GO:0006836; GO:0016192,integral to membrane; intracellular protein transport; neurotransmitter transport; vesicle-mediated transport,PF05739;PF00804;,,,,,,,,,STX_APLCA,Aplysia californica (California sea hare),intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter transport [GO:0006836]; regulation of exocytosis [GO:0017157]; vesicle-mediated transport [GO:0016192] comp108244_c0_seq1,746,46.6488,0.72241434,29,18,,5.00E-131,Q62915,Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase),Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase),GO:0005524; GO:0005516; GO:0004683; GO:0060170; GO:0005829; GO:0030425; GO:0006886; GO:0005634; GO:0042734; GO:0008022; GO:0043234; GO:0006461; GO:0003713,ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; cilium membrane; cytosol; dendrite; intracellular protein transport; nucleus; presynaptic membrane; protein C-terminus binding; protein complex; protein complex assembly; transcription coactivator activity,PF00625;PF02828;PF00595;PF00069;PF07653;,1.00E-139,CHOYP_CSKP.2.2,,,,,,,CSKP_RAT,Rattus norvegicus (Rat),intracellular protein transport [GO:0006886]; protein complex assembly [GO:0006461] comp108250_c1_seq1,872,45.2982,0.33649443,19,22,,4.00E-116,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,9.00E-137,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp108251_c2_seq1,241,46.888,0.54018787,5,23,,3.00E-08,Q07071,Glucokinase regulatory protein (Glucokinase regulator),Glucokinase regulatory protein (Glucokinase regulator),GO:0030246; GO:0001678; GO:0005829; GO:0051594; GO:0019899; GO:0004857; GO:0070095; GO:0006006; GO:0005739; GO:0033132; GO:0005654; GO:0033133; GO:0000060; GO:0009750,"carbohydrate binding; cellular glucose homeostasis; cytosol; detection of glucose; enzyme binding; enzyme inhibitor activity; fructose-6-phosphate binding; glucose metabolic process; mitochondrion; negative regulation of glucokinase activity; nucleoplasm; positive regulation of glucokinase activity; protein import into nucleus, translocation; response to fructose stimulus",,,,,,,,,,GCKR_RAT,Rattus norvegicus (Rat),"cellular glucose homeostasis [GO:0001678]; detection of glucose [GO:0051594]; glucose metabolic process [GO:0006006]; negative regulation of catalytic activity [GO:0043086]; negative regulation of glucokinase activity [GO:0033132]; positive regulation of glucokinase activity [GO:0033133]; protein import into nucleus, translocation [GO:0000060]; response to fructose [GO:0009750]" comp108252_c0_seq1,444,40.7658,0.60298409,2,0,,5.00E-27,Q68CP4,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0005975; GO:0006027; GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0044281; GO:0016746,"carbohydrate metabolic process; glycosaminoglycan catabolic process; heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; small molecule metabolic process; transferase activity, transferring acyl groups",PF07786;,7.00E-27,CHOYP_HGSNAT.1.2,,,,,,,HGNAT_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp108256_c1_seq1,203,45.3202,0.67775731,3,20,,1.00E-13,Q32KH8,Arylsulfatase H (ASH) (EC 3.1.6.-),Arylsulfatase H (ASH) (EC 3.1.6.-),GO:0016021; GO:0046872; GO:0008484,integral to membrane; metal ion binding; sulfuric ester hydrolase activity,PF00884;,,,,,,,,,ARSH_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),metabolic process [GO:0008152] comp108263_c0_seq2,363,31.405,0.22580817,26,0,,,,,,,,,,,7.00E-11,ruditapes_c4549,,,,,,, comp108265_c1_seq1,389,44.7301,0.20886468,2,17,,2.00E-26,Q9VH08,NAD-dependent protein deacetylase Sirt6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6),NAD-dependent protein deacetylase Sirt6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6),GO:0070403; GO:0008340; GO:0016787; GO:0046872,NAD+ binding; determination of adult lifespan; hydrolase activity; metal ion binding,PF02146;,,,,,,,,,SIR6_DROME,Drosophila melanogaster (Fruit fly),determination of adult lifespan [GO:0008340]; histone deacetylation [GO:0016575]; positive regulation of chromatin silencing [GO:0031937] comp108265_c1_seq2,279,43.7276,0.07827889,0,0,,2.00E-06,Q94AQ6,NAD-dependent protein deacetylase SRT2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2),NAD-dependent protein deacylase SRT2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2),GO:0070403; GO:0016787; GO:0046872; GO:0005759; GO:0005634,NAD+ binding; hydrolase activity; metal ion binding; mitochondrial matrix; nucleus,PF02146;,,,,,,,,,SIR4_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ADP-ribosylation [GO:0006471] comp108265_c3_seq1,409,42.5428,0.61169496,5,16,,2.00E-55,Q0P595,NAD-dependent protein deacetylase sirtuin-7 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7),NAD-dependent protein deacetylase sirtuin-7 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7),GO:0070403; GO:0097372; GO:0003682; GO:0005737; GO:0070932; GO:0046872; GO:0000122; GO:0005731; GO:0007072; GO:0009303,NAD+ binding; NAD-dependent histone deacetylase activity (H3-K18 specific); chromatin binding; cytoplasm; histone H3 deacetylation; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleolus organizer region; positive regulation of transcription on exit from mitosis; rRNA transcription,PF02146;,2.00E-34,CHOYP_SIR7.1.1,,,,,,,SIR7_BOVIN,Bos taurus (Bovine),histone H3 deacetylation [GO:0070932]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription involved in exit from mitosis [GO:0007072]; rRNA transcription [GO:0009303] comp108268_c1_seq1,937,41.7289,0.45353012,38,28,,5.00E-09,A1L1R5,Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),GO:0030030; GO:0035335; GO:0004725; GO:0008138,cell projection organization; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,,,,,,,,,PTPC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium morphogenesis [GO:0060271] comp108271_c0_seq1,356,39.3258,0.60050936,0,40,,3.00E-14,Q8VBX4,C-type lectin domain family 4 member K (Langerin) (CD antigen CD207),C-type lectin domain family 4 member K (Langerin) (CD antigen CD207),GO:0030246; GO:0051607; GO:0005887,carbohydrate binding; defense response to virus; integral to plasma membrane,PF00059;,,,,,,,,,CLC4K_MOUSE,Mus musculus (Mouse),defense response to virus [GO:0051607] comp108271_c0_seq2,293,41.6382,0.40385086,2,9,,3.00E-11,Q6ZS10,"C-type lectin domain family 17, member A (Prolectin)","C-type lectin domain family 17, member A (Prolectin)",GO:0009986; GO:0042806; GO:0016021; GO:0005537; GO:0046872,cell surface; fucose binding; integral to membrane; mannose binding; metal ion binding,PF00059;,,,,,,,,,CL17A_HUMAN,Homo sapiens (Human), comp108276_c0_seq1,615,39.3496,0.59702477,15,38,,3.00E-33,Q562C4,Methyltransferase-like protein 7B (EC 2.1.1.-) (Associated with lipid droplet protein 1) (ALDI),Methyltransferase-like protein 7B (EC 2.1.1.-) (Associated with lipid droplet protein 1) (ALDI),GO:0005789; GO:0005811; GO:0008168,endoplasmic reticulum membrane; lipid particle; methyltransferase activity,PF08241;,,,,,,,,,MET7B_RAT,Rattus norvegicus (Rat),methylation [GO:0032259] comp108281_c0_seq1,471,41.8259,0.72974973,2,0,,,,,,,,,1.00E-18,CHOYP_LOC100906981.1.1,,,,,,,,, comp108281_c1_seq1,513,43.8596,0.53260206,29,4,,6.00E-63,Q6IWH7,Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G),Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G),GO:0030054; GO:0005254; GO:0005829; GO:0005783; GO:0016021; GO:0034220; GO:0005634; GO:0005886,cell junction; chloride channel activity; cytosol; endoplasmic reticulum; integral to membrane; ion transmembrane transport; nucleus; plasma membrane,PF16178;PF04547;,2.00E-67,CHOYP_LOC100906981.1.1,,,,,,,ANO7_HUMAN,Homo sapiens (Human),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220] comp108291_c0_seq1,650,42.6154,0.78425704,30,20,,2.00E-79,O14936,Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog),Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog),GO:0005524; GO:0015629; GO:0005604; GO:0016323; GO:0070509; GO:0007155; GO:0005911; GO:0060170; GO:0005737; GO:0005829; GO:0030198; GO:0004385; GO:0001953; GO:0090288; GO:0010839; GO:0061045; GO:0005652; GO:0016363; GO:0005730; GO:0090280; GO:0045944; GO:0042734; GO:0004674,ATP binding; actin cytoskeleton; basement membrane; basolateral plasma membrane; calcium ion import; cell adhesion; cell-cell junction; cilium membrane; cytoplasm; cytosol; extracellular matrix organization; guanylate kinase activity; negative regulation of cell-matrix adhesion; negative regulation of cellular response to growth factor stimulus; negative regulation of keratinocyte proliferation; negative regulation of wound healing; nuclear lamina; nuclear matrix; nucleolus; positive regulation of calcium ion import; positive regulation of transcription from RNA polymerase II promoter; presynaptic membrane; protein serine/threonine kinase activity,PF00625;PF02828;PF00595;PF00069;PF07653;,9.00E-78,CHOYP_CSKP.1.2,,,,,,,CSKP_HUMAN,Homo sapiens (Human),calcium ion import [GO:0070509]; cell adhesion [GO:0007155]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion import [GO:0090280]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp108314_c0_seq1,335,39.7015,0.25740781,9,40,,2.00E-15,Q32KV6,Nucleotide exchange factor SIL1,Nucleotide exchange factor SIL1,GO:0005788; GO:0015031,endoplasmic reticulum lumen; protein transport,,,,,,,,,,SIL1_BOVIN,Bos taurus (Bovine),protein transport [GO:0015031] comp108317_c0_seq3,408,41.1765,0.23199232,0,0,,1.00E-39,A0NGI1,Transmembrane protein 234 homolog,Transmembrane protein 234 homolog,GO:0016021,integral to membrane,PF10639;,5.00E-15,CHOYP_LOC100744068.1.1,,,,,,,TM234_ANOGA,Anopheles gambiae (African malaria mosquito),transmembrane transport [GO:0055085] comp108318_c0_seq1,459,47.0588,0.3349124,24,30,,3.00E-19,Q2TAC2,Coiled-coil domain-containing protein 57,Coiled-coil domain-containing protein 57,,,,9.00E-13,CHOYP_LOC100368744.1.1,,,,,,,CCD57_HUMAN,Homo sapiens (Human), comp108335_c0_seq1,652,46.0123,0.6148239,53,19,,2.00E-78,Q3Y4E2,Selenoprotein N (SePN) (SelN),Selenoprotein N (SePN) (SelN),GO:0016021; GO:0048741,integral to membrane; skeletal muscle fiber development,,6.00E-30,CHOYP_SELN.1.1,,,,,,,SELN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),calcium-mediated signaling [GO:0019722]; muscle fiber development [GO:0048747]; muscle tissue development [GO:0060537]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; skeletal muscle fiber development [GO:0048741] comp108338_c0_seq1,664,43.3735,0.25660872,21,5,,1.00E-75,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,1.00E-57,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp108358_c0_seq1,482,40.6639,0.31486446,13,22,,2.00E-11,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,4.00E-18,CHOYP_LOC100887947.1.2,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp108381_c0_seq1,650,43.6923,0.25984196,28,7,,5.00E-59,Q569U0,Unconventional myosin-XIX,Unconventional myosin-XIX,GO:0005524; GO:0005741; GO:0003774; GO:0016459,ATP binding; mitochondrial outer membrane; motor activity; myosin complex,PF00612;PF00063;,,,,,,,,,MYO19_XENLA,Xenopus laevis (African clawed frog), comp108385_c0_seq1,860,43.8372,0.29123954,39,9,,8.00E-44,O46606,Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),GO:0005737; GO:0016787; GO:0016042; GO:0046872,cytoplasm; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;,5.00E-19,CHOYP_DDHD1.1.1,,,,,,,DDHD1_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042] comp108413_c0_seq1,387,42.3773,0.70513874,23,35,,2.00E-58,Q2T9X1,DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide) (DNA-directed RNA polymerase III subunit H),DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide) (DNA-directed RNA polymerase III subunit H),GO:0003677; GO:0003899; GO:0051607; GO:0045087; GO:0005634; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; defense response to virus; innate immune response; nucleus; transcription, DNA-dependent",PF08292;PF03876;,7.00E-64,CHOYP_BRAFLDRAFT_104488.1.3,,,,,,,RPC8_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; transcription initiation from RNA polymerase III promoter [GO:0006384] comp108416_c0_seq2,301,36.2126,0.81512371,0,7,,,,,,,,,,,1.00E-12,ruditapes_c9625,,,,,,, comp108426_c1_seq1,1004,45.1195,0.48986206,14,103,,9.00E-09,Q6RFZ7,Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Neuronal RhoA GEF protein) (Transcript highly enriched in cortex and hippocampus),Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Neuronal RhoA GEF protein) (Transcript highly enriched in cortex and hippocampus),GO:0005089; GO:0005911; GO:0030139; GO:0035767; GO:0030027; GO:0048471; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell-cell junction; endocytic vesicle; endothelial cell chemotaxis; lamellipodium; perinuclear region of cytoplasm; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,,,,,,,,,PKHG5_RAT,Rattus norvegicus (Rat),endothelial cell chemotaxis [GO:0035767]; regulation of Rho protein signal transduction [GO:0035023] comp108441_c0_seq1,735,39.8639,0.54869172,22,68,,3.00E-92,Q5NDL2,EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),GO:0005788; GO:0016262; GO:0006493,endoplasmic reticulum lumen; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation,PF04577;,6.00E-30,CHOYP_MED24.4.10,,,,,,,EOGT_HUMAN,Homo sapiens (Human),protein O-linked glycosylation [GO:0006493] comp108442_c0_seq1,352,39.7727,0.3996862,7,13,,3.00E-24,P23025,DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein),DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein),GO:0003684; GO:0008630; GO:0046872; GO:0035264; GO:0005654; GO:0000166; GO:0000718; GO:0009411; GO:0006979; GO:0009636,"damaged DNA binding; intrinsic apoptotic signaling pathway in response to DNA damage; metal ion binding; multicellular organism growth; nucleoplasm; nucleotide binding; nucleotide-excision repair, DNA damage removal; response to UV; response to oxidative stress; response to toxic substance",PF05181;PF01286;,3.00E-11,CHOYP_XPA.1.1,,,,,,,XPA_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; response to auditory stimulus [GO:0010996]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV-damage excision repair [GO:0070914]" comp108449_c0_seq1,305,41.3115,0.4000043,8,42,,2.00E-17,Q2YDR3,Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3),Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3),GO:0006021; GO:0008934; GO:0052832; GO:0052833; GO:0016021; GO:0046872; GO:0046854,inositol biosynthetic process; inositol monophosphate 1-phosphatase activity; inositol monophosphate 3-phosphatase activity; inositol monophosphate 4-phosphatase activity; integral to membrane; metal ion binding; phosphatidylinositol phosphorylation,PF00459;,2.00E-13,CHOYP_BRAFLDRAFT_119617.1.1,,,,,,,IMPA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),inositol biosynthetic process [GO:0006021]; phosphatidylinositol phosphorylation [GO:0046854] comp108449_c1_seq1,311,44.0514,0.33650046,8,7,,9.00E-17,D4AD37,Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (EC 3.1.3.7) (Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase) (Golgi-resident PAP phosphatase) (gPAPP) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3),Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (EC 3.1.3.7) (Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase) (Golgi-resident PAP phosphatase) (gPAPP) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3),GO:0008441; GO:0005794; GO:0006021; GO:0008934; GO:0052832; GO:0052833; GO:0016021; GO:0046872; GO:0046854,"3'(2'),5'-bisphosphate nucleotidase activity; Golgi apparatus; inositol biosynthetic process; inositol monophosphate 1-phosphatase activity; inositol monophosphate 3-phosphatase activity; inositol monophosphate 4-phosphatase activity; integral to membrane; metal ion binding; phosphatidylinositol phosphorylation",PF00459;,,,,,,,,,IMPA3_RAT,Rattus norvegicus (Rat),inositol biosynthetic process [GO:0006021]; phosphatidylinositol phosphorylation [GO:0046854] comp108457_c0_seq2,437,46.2243,0.42975107,3,27,,5.00E-51,Q3B7L5,Folliculin,Folliculin,GO:0031929; GO:0007043; GO:0005737; GO:0030097; GO:0001701; GO:2001170; GO:0070373; GO:0035024; GO:0032007; GO:0030308; GO:0030336; GO:1901723; GO:1901856; GO:2000506; GO:1901859; GO:0010823; GO:1901862; GO:1901874; GO:0051898; GO:1900181; GO:0000122; GO:0005634; GO:0005886; GO:0032008; GO:0043065; GO:0045785; GO:0001934; GO:0045944; GO:0030511; GO:0032403; GO:0032465; GO:0035065; GO:2000973,TOR signaling cascade; cell-cell junction assembly; cytoplasm; hemopoiesis; in utero embryonic development; negative regulation of ATP biosynthetic process; negative regulation of ERK1 and ERK2 cascade; negative regulation of Rho protein signal transduction; negative regulation of TOR signaling cascade; negative regulation of cell growth; negative regulation of cell migration; negative regulation of cell proliferation involved in kidney development; negative regulation of cellular respiration; negative regulation of energy homeostasis; negative regulation of mitochondrial DNA metabolic process; negative regulation of mitochondrion organization; negative regulation of muscle tissue development; negative regulation of post-translational protein modification; negative regulation of protein kinase B signaling cascade; negative regulation of protein localization to nucleus; negative regulation of transcription from RNA polymerase II promoter; nucleus; plasma membrane; positive regulation of TOR signaling cascade; positive regulation of apoptotic process; positive regulation of cell adhesion; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; protein complex binding; regulation of cytokinesis; regulation of histone acetylation; regulation of pro-B cell differentiation,PF16692;,3.00E-38,CHOYP_FLCN.1.1,,,,,,,FLCN_BOVIN,Bos taurus (Bovine),cell-cell junction assembly [GO:0007043]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in kidney development [GO:1901723]; negative regulation of cellular respiration [GO:1901856]; negative regulation of energy homeostasis [GO:2000506]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of gene expression [GO:0010629]; negative regulation of mitochondrial DNA metabolic process [GO:1901859]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of post-translational protein modification [GO:1901874]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cytokinesis [GO:0032465]; regulation of histone acetylation [GO:0035065]; regulation of pro-B cell differentiation [GO:2000973]; regulation of protein phosphorylation [GO:0001932]; regulation of TOR signaling [GO:0032006]; TOR signaling [GO:0031929] comp108460_c0_seq1,227,40.0881,1.22343838,0,14,,7.00E-10,Q7TSH7,Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1),Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1),GO:0005251; GO:0051260; GO:0008076,delayed rectifier potassium channel activity; protein homooligomerization; voltage-gated potassium channel complex,PF02214;PF00520;,,,,,,,,,KCNF1_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp108460_c2_seq1,285,42.807,0.922592,8,9,,5.00E-17,Q63959,Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3),Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3),GO:0030673; GO:0043679; GO:0005251; GO:0032590; GO:0031594; GO:0032809; GO:0051260; GO:0046928; GO:0008076,axolemma; axon terminus; delayed rectifier potassium channel activity; dendrite membrane; neuromuscular junction; neuronal cell body membrane; protein homooligomerization; regulation of neurotransmitter secretion; voltage-gated potassium channel complex,PF02214;PF00520;PF11404;,6.00E-19,CHOYP_KCNAW.1.1,,,,,,,KCNC3_MOUSE,Mus musculus (Mouse),potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of neurotransmitter secretion [GO:0046928] comp108470_c0_seq2,329,45.5927,0.37351788,5,11,,2.00E-22,Q3URF8,BTB/POZ domain-containing protein KCTD21,BTB/POZ domain-containing protein KCTD21,GO:0051260,protein homooligomerization,PF02214;,4.00E-34,CHOYP_LOC100377510.4.4,8.00E-60,ruditapes_c9449,,,,,KCD21_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp108476_c1_seq1,570,42.6316,0.28128165,21,22,,2.00E-30,Q4KLI9,F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),GO:0080008; GO:0019005; GO:0031146; GO:0051298; GO:0005737; GO:0016567,Cul4-RING ubiquitin ligase complex; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication; cytoplasm; protein ubiquitination,PF12937;PF00400;,2.00E-34,CHOYP_LOC412155.1.2,,,,,,,FBXW5_RAT,Rattus norvegicus (Rat),centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp108479_c1_seq1,635,36.2205,1.09099686,21,6,,7.00E-25,Q25414,5-hydroxytryptamine receptor (5-HT receptor) (Serotonin receptor),5-hydroxytryptamine receptor (5-HT receptor) (Serotonin receptor),GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00001;,,,,,,,,,5HTR_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis), comp108487_c0_seq1,1532,34.3342,0.42406657,3242,458,,1.00E-80,Q8TC29,Enkurin,Enkurin,GO:0005929,cilium,PF13864;,6.00E-72,CHOYP_LOC578858.1.2,7.00E-132,ruditapes_c16869,6.00E-71,ES789247.p.cg.6,5,,ENKUR_HUMAN,Homo sapiens (Human), comp108506_c1_seq1,422,44.0758,0.44062747,5,35,,1.00E-46,Q00526,Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3),Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3),GO:0005524; GO:0045023; GO:0000082; GO:0051301; GO:0008283; GO:0004693; GO:0007067,ATP binding; G0 to G1 transition; G1/S transition of mitotic cell cycle; cell division; cell proliferation; cyclin-dependent protein serine/threonine kinase activity; mitosis,PF00069;,9.00E-19,CHOYP_LOC101068677.1.1,,,,,,,CDK3_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; G0 to G1 transition [GO:0045023]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067] comp108506_c2_seq1,501,40.519,0.64169381,7,41,,3.00E-68,Q6DJM7,Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14),Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14),GO:0005524; GO:0000086; GO:0016055; GO:0051301; GO:0004693; GO:0000308; GO:0005886; GO:0060828,ATP binding; G2/M transition of mitotic cell cycle; Wnt receptor signaling pathway; cell division; cyclin-dependent protein serine/threonine kinase activity; cytoplasmic cyclin-dependent protein kinase holoenzyme complex; plasma membrane; regulation of canonical Wnt receptor signaling pathway,PF00069;,3.00E-76,CHOYP_LOC657012.1.1,,,,,,,CDK14_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] comp108509_c1_seq1,733,41.8827,0.43649729,16,0,,2.00E-09,Q5ZLN7,Protein FAM122A,Protein FAM122A,,,,1.00E-14,CHOYP_FAM122B.1.1,,,,,,,F122A_CHICK,Gallus gallus (Chicken), comp108510_c1_seq1,706,44.4759,0.63850703,29,9,,3.00E-33,Q9ULI1,Leucine-rich repeat and WD repeat-containing protein KIAA1239,NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239),,,PF13271;,1.00E-83,CHOYP_LOC100744637.1.1,,,,,,,K1239_HUMAN,Homo sapiens (Human), comp108514_c0_seq1,384,43.2292,0.4470926,9,18,,4.00E-30,Q9P2D8,Protein unc-79 homolog,Protein unc-79 homolog,GO:0048149; GO:0016021; GO:0034220; GO:0035264; GO:0005886,behavioral response to ethanol; integral to membrane; ion transmembrane transport; multicellular organism growth; plasma membrane,,4.00E-42,CHOYP_UNC79.4.4,,,,,,,UNC79_HUMAN,Homo sapiens (Human),behavioral response to ethanol [GO:0048149]; ion transmembrane transport [GO:0034220]; multicellular organism growth [GO:0035264] comp108514_c2_seq1,336,46.4286,0.11168285,4,0,,,,,,,,,1.00E-34,CHOYP_UNC79.2.4,,,,,,,,, comp108518_c0_seq1,560,40.7143,0.5618662,10,53,,,,,,,,,6.00E-29,CHOYP_LOC100370244.4.4,,,,,,,,, comp108518_c1_seq1,1046,42.9254,0.71787595,28,101,,6.00E-93,Q9EPS3,D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase),D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase),GO:0000139; GO:0050379; GO:0015012; GO:0030210; GO:0047464; GO:0016021,Golgi membrane; UDP-glucuronate 5'-epimerase activity; heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; heparosan-N-sulfate-glucuronate 5-epimerase activity; integral to membrane,PF06662;,4.00E-21,CHOYP_LOC100370244.1.4,,,,,,,GLCE_MOUSE,Mus musculus (Mouse),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] comp108533_c0_seq1,231,54.1126,1.24925418,0,29,,1.00E-20,P20483,M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string),M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string),GO:0000086; GO:0007030; GO:0051301; GO:0008283; GO:0007099; GO:0005694; GO:0007369; GO:0046331; GO:0007498; GO:0007067; GO:0045792; GO:0045930; GO:0005634; GO:0007424; GO:0007422; GO:0008284; GO:0045977; GO:0004725; GO:0008138; GO:0060305,"G2/M transition of mitotic cell cycle; Golgi organization; cell division; cell proliferation; centriole replication; chromosome; gastrulation; lateral inhibition; mesoderm development; mitosis; negative regulation of cell size; negative regulation of mitotic cell cycle; nucleus; open tracheal system development; peripheral nervous system development; positive regulation of cell proliferation; positive regulation of mitotic cell cycle, embryonic; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of cell diameter",PF00581;,,,,,,,,,MPIP_DROME,Drosophila melanogaster (Fruit fly),"cell division [GO:0051301]; cell proliferation [GO:0008283]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; histoblast morphogenesis [GO:0007488]; lateral inhibition [GO:0046331]; mesoderm development [GO:0007498]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; negative regulation of cell size [GO:0045792]; negative regulation of mitotic cell cycle [GO:0045930]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cell cycle, embryonic [GO:0045977]; protein dephosphorylation [GO:0006470]; regulation of cell diameter [GO:0060305]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]" comp108534_c1_seq1,515,42.7184,1.33300503,8,57,,,,,,,,,1.00E-42,CHOYP_LOC100869441.2.2,,,,,,,,, comp108543_c0_seq1,208,61.5385,1.07260544,0,5,,2.00E-14,P75919,Uncharacterized protein YmdC,Cardiolipin synthase C (CL synthase) (EC 2.7.8.-),GO:0032049; GO:0090483,cardiolipin biosynthetic process; phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity,PF13091;,,,,,,,,,YMDC_ECOLI,Escherichia coli (strain K12),cardiolipin biosynthetic process [GO:0032049] comp108553_c0_seq1,1304,41.0276,0.40841608,2,42,,2.00E-157,Q9Y484,WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45),WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45),GO:0000045; GO:0008219; GO:0005737; GO:0080025; GO:0032266,"autophagic vacuole assembly; cell death; cytoplasm; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding",PF00400;,1.00E-111,CHOYP_WIPI4.1.1,,,,,,,WIPI4_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497] comp108569_c0_seq1,660,39.8485,0.3899714,14,61,,7.00E-55,Q7ZW24,"GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)","GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)",GO:0004377; GO:0009058; GO:0016021,"GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity; biosynthetic process; integral to membrane",PF15924;PF00534;,7.00E-29,CHOYP_ALG11.1.1,,,,,,,ALG11_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp108588_c1_seq1,399,44.8622,1.01010735,11,13,,8.00E-13,Q9UDV7,Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1),Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1),GO:0003677; GO:0045892; GO:0005634; GO:0006351; GO:0008270,"DNA binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent; zinc ion binding",PF12417;PF01352;PF00096;PF13912;,,,,,,,,,ZN282_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108597_c1_seq1,316,46.519,0.54137165,4,6,,1.00E-46,Q8N187,Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24),Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24),GO:0003677; GO:0035865; GO:0005730; GO:0005654; GO:0005634; GO:0061400; GO:0003700; GO:0006351,"DNA binding; cellular response to potassium ion; nucleolus; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF15299;,1.00E-35,CHOYP_BRAFLDRAFT_82864.1.1,,,,,,,AL2S8_HUMAN,Homo sapiens (Human),cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400] comp108600_c0_seq1,479,45.5115,0.80338617,16,1,,6.00E-28,Q9LV03,"Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)","Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)",GO:0051538; GO:0010181; GO:0097054; GO:0019676; GO:0009570; GO:0048589; GO:0050660; GO:0006537; GO:0016040; GO:0005506; GO:0046686,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; ammonia assimilation cycle; chloroplast stroma; developmental growth; flavin adenine dinucleotide binding; glutamate biosynthetic process; glutamate synthase (NADH) activity; iron ion binding; response to cadmium ion",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,3.00E-31,CHOYP_BRAFLDRAFT_129259.1.1,,,,,,,GLUT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),ammonia assimilation cycle [GO:0019676]; developmental growth [GO:0048589]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]; response to cadmium ion [GO:0046686]; response to cytokinin [GO:0009735] comp108604_c0_seq1,1044,42.5287,0.53220795,34,75,,8.00E-17,Q52KF3,Protein spire homolog 1,Protein spire homolog 1,GO:0005794; GO:0048193; GO:0005938; GO:0036089; GO:0030659; GO:0005856; GO:0005829; GO:0051295; GO:0070649; GO:0048471; GO:0005886; GO:0040038; GO:0015031,Golgi apparatus; Golgi vesicle transport; cell cortex; cleavage furrow formation; cytoplasmic vesicle membrane; cytoskeleton; cytosol; establishment of meiotic spindle localization; formin-nucleated actin cable assembly; perinuclear region of cytoplasm; plasma membrane; polar body extrusion after meiotic divisions; protein transport,PF16474;,3.00E-30,CHOYP_ISCW_ISCW003557.1.1,,,,,,,SPIR1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; Golgi vesicle transport [GO:0048193]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp108605_c0_seq1,367,43.8692,0.47963862,4,14,,1.00E-32,Q3UYK3,TBC1 domain family member 9,TBC1 domain family member 9,GO:0005097; GO:0005509; GO:0032851,Rab GTPase activator activity; calcium ion binding; positive regulation of Rab GTPase activity,PF02893;PF00566;,2.00E-44,CHOYP_BRAFLDRAFT_153908.1.2,,,,,,,TBCD9_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp108605_c1_seq1,224,41.5179,0.46827156,6,16,,,,,,,,,,,2.00E-22,ruditapes_c11453,,,,,,, comp108612_c0_seq1,302,44.702,0.40708015,6,17,,1.00E-16,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,,,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp108629_c1_seq1,513,43.0799,0.84276431,13,5,,4.00E-51,O88866,Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V),Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V),GO:0005524; GO:0004672; GO:0004674,ATP binding; protein kinase activity; protein serine/threonine kinase activity,PF00069;,,,,,,,,,HUNK_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp108633_c0_seq1,387,43.4109,0.60487932,0,54,,1.00E-08,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,,,,,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp108637_c0_seq1,1031,46.8477,0.51940347,39,0,,4.00E-24,Q3ULW6,Coiled-coil domain-containing protein 33 (Speriolin-binding factor),Coiled-coil domain-containing protein 33 (Speriolin-binding factor),GO:0005777; GO:0007283,peroxisome; spermatogenesis,PF00168;,,,,,,,,,CCD33_MOUSE,Mus musculus (Mouse),spermatogenesis [GO:0007283] comp108637_c0_seq2,1005,44.3781,0.44513318,36,0,,9.00E-22,Q5XIR4,Coiled-coil domain-containing protein 33,Coiled-coil domain-containing protein 33,,,PF00168;,2.00E-18,CHOYP_BRAFLDRAFT_118966.1.1,,,,,,,CCD33_RAT,Rattus norvegicus (Rat), comp108641_c0_seq1,592,48.8176,0.76754773,22,32,,4.00E-53,Q7Z3G6,Prickle-like protein 2,Prickle-like protein 2,GO:0016327; GO:0005737; GO:0045197; GO:0016328; GO:0031175; GO:0031965; GO:0008270,apicolateral plasma membrane; cytoplasm; establishment or maintenance of epithelial cell apical/basal polarity; lateral plasma membrane; neuron projection development; nuclear membrane; zinc ion binding,PF00412;PF06297;,,,,,,,,,PRIC2_HUMAN,Homo sapiens (Human),"Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp108641_c1_seq1,904,41.9248,0.56636583,16,34,,2.00E-72,O35115,Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3),Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3),GO:0031430; GO:0030018; GO:0015629; GO:0055014; GO:0005925; GO:0060347; GO:0043066; GO:0000122; GO:0005634; GO:0001649; GO:0009725; GO:0008134; GO:0006351; GO:0055015; GO:0008270,"M band; Z disc; actin cytoskeleton; atrial cardiac muscle cell development; focal adhesion; heart trabecula formation; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; osteoblast differentiation; response to hormone stimulus; transcription factor binding; transcription, DNA-dependent; ventricular cardiac muscle cell development; zinc ion binding",PF00412;,4.00E-128,CHOYP_LOC100160412.1.2,,,,,,,FHL2_RAT,Rattus norvegicus (Rat),"atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]; ventricular cardiac muscle cell development [GO:0055015]" comp108641_c1_seq2,251,46.2151,0.46324265,2,0,,,,,,,,,1.00E-46,CHOYP_LOC100160412.1.2,,,,,,,,, comp108651_c1_seq1,408,42.8922,0.86287438,10,33,,3.00E-45,Q8MV48,N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),GO:0000139; GO:0005795; GO:0016021; GO:0009312; GO:0004653; GO:0006486,Golgi membrane; Golgi stack; integral to membrane; oligosaccharide biosynthetic process; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,5.00E-41,CHOYP_DWIL_GK25256.1.1,,,,,,,GALT7_DROME,Drosophila melanogaster (Fruit fly),oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] comp108654_c0_seq1,527,37.1917,0.27722456,34,26,,3.00E-07,P70399,Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1),Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1),GO:0006281; GO:0000777; GO:0003684; GO:0000776; GO:0035064; GO:0005634; GO:0006355; GO:0005657; GO:0042162; GO:0008134; GO:0006351,"DNA repair; condensed chromosome kinetochore; damaged DNA binding; kinetochore; methylated histone residue binding; nucleus; regulation of transcription, DNA-dependent; replication fork; telomeric DNA binding; transcription factor binding; transcription, DNA-dependent",PF09038;,,,,,,,,,TP53B_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108661_c0_seq1,421,41.5677,0.50478754,2,77,,2.00E-09,Q80VM7,Ankyrin repeat domain-containing protein 24,Ankyrin repeat domain-containing protein 24,,,PF00023;PF12796;,1.00E-17,CHOYP_LOC100371977.1.1,,,,,,,ANR24_MOUSE,Mus musculus (Mouse), comp108692_c0_seq1,545,41.6514,0.55410023,15,29,,5.00E-25,Q80W94,2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like) (Monoacylglycerol O-acyltransferase 2),2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like) (Monoacylglycerol O-acyltransferase 2),GO:0003846; GO:0016407; GO:0006651; GO:0005783; GO:0005789; GO:0006071; GO:0016021; GO:0050892; GO:0046462; GO:0019432,2-acylglycerol O-acyltransferase activity; acetyltransferase activity; diacylglycerol biosynthetic process; endoplasmic reticulum; endoplasmic reticulum membrane; glycerol metabolic process; integral to membrane; intestinal absorption; monoacylglycerol metabolic process; triglyceride biosynthetic process,PF03982;,,,,,,,,,MOGT2_MOUSE,Mus musculus (Mouse),diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; intestinal absorption [GO:0050892]; lipid metabolic process [GO:0006629]; monoacylglycerol metabolic process [GO:0046462]; triglyceride biosynthetic process [GO:0019432] comp108694_c1_seq1,225,46.2222,0.58702458,7,11,,3.00E-12,Q8C7R4,Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2),Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2),GO:0005524; GO:0019780; GO:0005737; GO:0016874; GO:0016567; GO:0006511,ATP binding; FAT10 activating enzyme activity; cytoplasm; ligase activity; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF16191;PF16190;PF09358;PF00899;PF10585;,,,,,,,,,UBA6_MOUSE,Mus musculus (Mouse),amygdala development [GO:0021764]; dendritic spine development [GO:0060996]; hippocampus development [GO:0021766]; learning [GO:0007612]; locomotory behavior [GO:0007626]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511] comp108702_c1_seq1,257,59.5331,1.14934028,0,12,,8.00E-11,O34399,Glutamate synthase [NADPH] small chain (EC 1.4.1.13) (NADPH-GOGAT),Glutamate synthase [NADPH] small chain (EC 1.4.1.13) (NADPH-GOGAT),GO:0097054; GO:0050660; GO:0004355; GO:0051536,L-glutamate biosynthetic process; flavin adenine dinucleotide binding; glutamate synthase (NADPH) activity; iron-sulfur cluster binding,PF14691;PF07992;,,,,,,,,,GLTB_BACSU,Bacillus subtilis (strain 168),L-glutamate biosynthetic process [GO:0097054] comp108710_c1_seq1,221,46.6063,0.16780389,0,17,,3.00E-24,Q96QE2,Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),GO:0016021; GO:0005886; GO:0022891; GO:0055085,integral to membrane; plasma membrane; substrate-specific transmembrane transporter activity; transmembrane transport,PF00083;,3.00E-46,CHOYP_MYCT.2.2,,,,,,,MYCT_HUMAN,Homo sapiens (Human),glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428] comp108725_c0_seq1,477,42.5577,0.29022593,12,22,,4.00E-20,Q9HAD4,WD repeat-containing protein 41,WD repeat-containing protein 41,GO:0005765,lysosomal membrane,PF00400;,,,,,,,,,WDR41_HUMAN,Homo sapiens (Human), comp108736_c0_seq1,713,42.6367,0.46942893,13,44,,6.00E-54,P83436,Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7),Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7),GO:0000139; GO:0017119; GO:0006886; GO:0006486; GO:0034067; GO:0050821; GO:0006890,"Golgi membrane; Golgi transport complex; intracellular protein transport; protein glycosylation; protein localization to Golgi apparatus; protein stabilization; retrograde vesicle-mediated transport, Golgi to ER",PF10191;,5.00E-82,CHOYP_LOC581128.1.1,,,,,,,COG7_HUMAN,Homo sapiens (Human),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp108737_c0_seq1,865,41.1561,0.52210128,42,56,,6.00E-18,Q9VJE5,Restin homolog (Cytoplasmic linker protein 190) (Microtubule-binding protein 190) (d-CLIP-190),Restin homolog (Cytoplasmic linker protein 190) (Microtubule-binding protein 190) (d-CLIP-190),GO:0005794; GO:0003779; GO:0007349; GO:0045169; GO:0000776; GO:0005875; GO:0051010; GO:0007017; GO:0005876,Golgi apparatus; actin binding; cellularization; fusome; kinetochore; microtubule associated complex; microtubule plus-end binding; microtubule-based process; spindle microtubule,PF01302;PF16641;,,,,,,,,,CL190_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; microtubule-based process [GO:0007017] comp108739_c1_seq1,284,41.1972,0.50147249,1,34,,5.00E-07,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp108740_c0_seq1,375,44,0.6127451,12,28,,6.00E-50,Q9DBV3,Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34),Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX34_MOUSE,Mus musculus (Mouse),"negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]" comp108740_c1_seq1,293,43.3447,0.80810537,11,3,,9.00E-10,O17438,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) (Fragment),Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) (Fragment),GO:0005524; GO:0008026; GO:0008380; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; mRNA processing; nucleic acid binding; nucleus,PF04408;PF00271;,5.00E-26,CHOYP_LOC586878.1.1,,,,,,,DHX15_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),"mRNA splicing, via spliceosome [GO:0000398]" comp108745_c0_seq1,1033,41.2391,0.54335311,15,15,,9.00E-69,Q9D845,Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1),Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1),,,,4.00E-91,CHOYP_LOC100892369.1.1,,,,,,,TEX9_MOUSE,Mus musculus (Mouse), comp108746_c0_seq2,346,44.2197,0.83299736,8,0,,3.00E-10,Q8K1C7,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT14_MOUSE,Mus musculus (Mouse), comp108748_c0_seq1,272,45.9559,0.70000946,1,13,,7.00E-06,Q6ZPR4,Potassium channel subfamily T member 1,Potassium channel subfamily T member 1,GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,,,,,,,,,KCNT1_MOUSE,Mus musculus (Mouse), comp108753_c0_seq1,415,39.5181,0.44608102,33,2,,8.00E-09,P29294,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_RABIT,Oryctolagus cuniculus (Rabbit), comp108755_c0_seq1,372,42.7419,0.59414255,2,13,,,,,,,,,2.00E-27,CHOYP_SLFN5.1.1,,,,,,,,, comp108775_c0_seq1,1212,35.4785,0.67835139,36,145,,4.00E-58,P35290,Ras-related protein Rab-24 (Rab-16),Ras-related protein Rab-24 (Rab-16),GO:0005525; GO:0005776; GO:0006914; GO:0005829; GO:0016020; GO:0005739; GO:0015031; GO:0007264,GTP binding; autophagic vacuole; autophagy; cytosol; membrane; mitochondrion; protein transport; small GTPase mediated signal transduction,PF00071;,1.00E-23,CHOYP_RAB24.1.1,,,,,,,RAB24_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp108776_c0_seq1,298,48.9933,0.45745399,0,25,,1.00E-08,P47179,Cell wall protein DAN4 (Delayed anaerobic protein 4),Cell wall protein DAN4 (Delayed anaerobic protein 4),GO:0031225; GO:0005576; GO:0009277; GO:0006950,anchored to membrane; extracellular region; fungal-type cell wall; response to stress,PF00660;,,,,,,,,,DAN4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),fungal-type cell wall organization [GO:0031505]; response to stress [GO:0006950] comp108776_c0_seq2,262,49.2366,0.5146846,0,10,,2.00E-07,P47179,Cell wall protein DAN4 (Delayed anaerobic protein 4),Cell wall protein DAN4 (Delayed anaerobic protein 4),GO:0031225; GO:0005576; GO:0009277; GO:0006950,anchored to membrane; extracellular region; fungal-type cell wall; response to stress,PF00660;,,,,,,,,,DAN4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),fungal-type cell wall organization [GO:0031505]; response to stress [GO:0006950] comp108784_c0_seq1,226,42.9204,0.86863946,0,22,,1.00E-11,O88871,Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51),Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51),GO:0004965; GO:0038039; GO:0030054; GO:0005737; GO:0007214; GO:0005887; GO:0043005; GO:0045211,G-protein coupled GABA receptor activity; G-protein coupled receptor heterodimeric complex; cell junction; cytoplasm; gamma-aminobutyric acid signaling pathway; integral to plasma membrane; neuron projection; postsynaptic membrane,PF00003;PF01094;,,,,,,,,,GABR2_RAT,Rattus norvegicus (Rat),gamma-aminobutyric acid signaling pathway [GO:0007214] comp108798_c1_seq1,555,42.7027,0.75392765,13,58,,2.00E-20,O88947,Coagulation factor X (EC 3.4.21.6) (Stuart factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain],Coagulation factor X (EC 3.4.21.6) (Stuart factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain],GO:0007596; GO:0005509; GO:0005576; GO:0006508; GO:0004252,blood coagulation; calcium ion binding; extracellular region; proteolysis; serine-type endopeptidase activity,PF00008;PF00594;PF00089;,,,,,,,,,FA10_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596]; positive regulation of protein kinase B signaling [GO:0051897] comp108798_c2_seq1,278,39.5683,0.48421314,8,3,,2.00E-10,Q3UKY7,Serine protease 38 (EC 3.4.21.-) (Marapsin-2),Serine protease 38 (EC 3.4.21.-) (Marapsin-2),GO:0005576; GO:0006508; GO:0004252,extracellular region; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,PRS38_MOUSE,Mus musculus (Mouse), comp108813_c0_seq1,229,51.9651,0.87736415,0,40,,3.00E-13,Q60519,Semaphorin-5B (Semaphorin-G) (Sema G),Semaphorin-5B (Semaphorin-G) (Sema G),GO:0030154; GO:0016021; GO:0007399; GO:0004872,cell differentiation; integral to membrane; nervous system development; receptor activity,PF01403;PF00090;,,,,,,,,,SEM5B_MOUSE,Mus musculus (Mouse),axon extension [GO:0048675]; detection of light stimulus involved in visual perception [GO:0050908]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526] comp108839_c0_seq1,271,46.1255,0.57023837,1,34,,2.00E-07,A8WHP3,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,,,,,,,,,SC5A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),sodium ion transport [GO:0006814] comp108850_c0_seq1,915,37.9235,0.45922515,45,102,,1.00E-78,Q5U3U3,"Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)","Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)",GO:0004095; GO:0006635; GO:0005743; GO:0006810,carnitine O-palmitoyltransferase activity; fatty acid beta-oxidation; mitochondrial inner membrane; transport,PF00755;,,,,,,,,,CPT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810] comp108852_c0_seq2,286,43.3566,0.38784258,5,0,,1.00E-09,Q6KAU4,Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B),Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B),GO:0031902; GO:0015031,late endosome membrane; protein transport,PF10240;,,,,,,,,,F125B_MOUSE,Mus musculus (Mouse),positive regulation of viral process [GO:0048524]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; virus maturation [GO:0019075] comp108856_c0_seq1,727,44.2916,0.42363427,8,27,,1.00E-23,Q62513,Zinc finger protein 260 (Zfp-260),Zinc finger protein 260 (Zfp-260),GO:0003677; GO:0005737; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN260_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108856_c0_seq2,527,42.8843,0.41402172,1,11,,5.00E-13,Q96N20,Zinc finger protein 75A,Zinc finger protein 75A,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN75A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108859_c0_seq1,548,39.2336,0.28608746,38,27,,9.00E-31,Q5F476,Uncharacterized protein C15orf41 homolog,Uncharacterized protein C15orf41 homolog,,,PF14811;,,,,,,,,,CO041_CHICK,Gallus gallus (Chicken), comp108868_c1_seq1,306,45.098,0.51629729,0,15,,2.00E-07,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp108878_c0_seq1,585,42.2222,0.46582012,2,0,,2.00E-24,Q9UHY8,Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2),Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2),GO:0007411; GO:0007165,axon guidance; signal transduction,PF07763;,,,,,,,,,FEZ2_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; negative regulation of autophagosome assembly [GO:1902902]; nervous system development [GO:0007399]; signal transduction [GO:0007165] comp108878_c0_seq2,486,41.1523,0.43900426,2,0,,,,,,,,,2.00E-28,CHOYP_LOC664535.1.1,,,,,,,,, comp108886_c1_seq1,610,49.5082,0.57610607,11,74,,1.00E-63,P22984,Amidase (EC 3.5.1.4),Amidase (EC 3.5.1.4),GO:0004040; GO:0016884,"amidase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor",PF01425;,1.00E-12,CHOYP_BRAFLDRAFT_94568.1.2,,,,,,,AMID_RHOER,Rhodococcus erythropolis (Arthrobacter picolinophilus), comp108888_c0_seq1,256,35.5469,0.37464129,1,45,,,,,,,,,1.00E-14,CHOYP_WU_FC28F08.1.1,,,,,,,,, comp108900_c2_seq1,201,45.2736,1.12349833,0,12,,3.00E-12,Q95R48,Organic cation transporter-like protein,Organic cation transporter-like protein,GO:0007390; GO:0016021; GO:0015101; GO:0030307; GO:0040018,germ-band shortening; integral to membrane; organic cation transmembrane transporter activity; positive regulation of cell growth; positive regulation of multicellular organism growth,PF00083;,,,,,,,,,OCTL_DROME,Drosophila melanogaster (Fruit fly),germ-band shortening [GO:0007390]; organic cation transport [GO:0015695]; positive regulation of cell growth [GO:0030307]; positive regulation of multicellular organism growth [GO:0040018] comp108902_c0_seq1,806,38.5856,0.33754444,3,123,,2.00E-50,Q6P3N9,Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7),Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7),GO:0005794; GO:0008324; GO:0016021; GO:0006829,Golgi apparatus; cation transmembrane transporter activity; integral to membrane; zinc ion transport,PF01545;,4.00E-71,CHOYP_BRAFLDRAFT_276675.1.1,,,,,,,ZNT7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp108908_c0_seq1,309,41.4239,0.90403916,0,53,,1.00E-12,P06787,Calmodulin (CaM),Calmodulin (CaM),GO:0006607; GO:0005509; GO:0048306; GO:0007114; GO:0005935; GO:0005934; GO:0005823; GO:0000131; GO:0000742; GO:0043332; GO:0016237; GO:0006661; GO:0006898; GO:0051300; GO:0042991; GO:0042144,"NLS-bearing protein import into nucleus; calcium ion binding; calcium-dependent protein binding; cell budding; cellular bud neck; cellular bud tip; central plaque of spindle pole body; incipient cellular bud site; karyogamy involved in conjugation with cellular fusion; mating projection tip; microautophagy; phosphatidylinositol biosynthetic process; receptor-mediated endocytosis; spindle pole body organization; transcription factor import into nucleus; vacuole fusion, non-autophagic",PF13499;,,,,,,,,,CALM_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"cell budding [GO:0007114]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; lysosomal microautophagy [GO:0016237]; NLS-bearing protein import into nucleus [GO:0006607]; phosphatidylinositol biosynthetic process [GO:0006661]; receptor-mediated endocytosis [GO:0006898]; regulation of membrane tubulation [GO:1903525]; spindle pole body organization [GO:0051300]; transcription factor import into nucleus [GO:0042991]; vacuole fusion, non-autophagic [GO:0042144]" comp108910_c0_seq1,358,45.2514,0.33841584,7,37,,2.00E-38,O43502,DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2),DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2),GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0008094; GO:0007596; GO:0008821; GO:0007066; GO:0007141; GO:0005739; GO:0005654; GO:0048471; GO:0007131; GO:0007062; GO:0007283,ATP binding; DNA binding; DNA recombination; DNA repair; DNA-dependent ATPase activity; blood coagulation; crossover junction endodeoxyribonuclease activity; female meiosis sister chromatid cohesion; male meiosis I; mitochondrion; nucleoplasm; perinuclear region of cytoplasm; reciprocal meiotic recombination; sister chromatid cohesion; spermatogenesis,PF08423;,,,,,,,,,RA51C_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; mitotic recombination [GO:0006312]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; sister chromatid cohesion [GO:0007062]; spermatogenesis [GO:0007283]; strand displacement [GO:0000732]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722] comp108920_c0_seq1,242,41.7355,0.57222327,11,0,,3.00E-08,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp108922_c0_seq1,286,46.5035,0.45556113,11,11,,2.00E-31,Q9HCS5,Band 4.1-like protein 4A (Protein NBL4),Band 4.1-like protein 4A (Protein NBL4),GO:0005737; GO:0005856; GO:0019898,cytoplasm; cytoskeleton; extrinsic to membrane,PF08736;PF09380;PF00373;PF09379;,,,,,,,,,E41LA_HUMAN,Homo sapiens (Human), comp108926_c0_seq1,799,39.0488,0.46252395,20,26,,3.00E-34,Q61116,Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93),Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,5.00E-57,CHOYP_BRAFLDRAFT_89152.1.1,,,,,,,ZN235_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp108941_c0_seq1,831,38.5078,0.58196266,300,972,,1.00E-86,Q9CZ15,DNA replication complex GINS protein PSF1 (GINS complex subunit 1),DNA replication complex GINS protein PSF1 (GINS complex subunit 1),GO:0006260; GO:0005737; GO:0001833; GO:0005634,DNA replication; cytoplasm; inner cell mass cell proliferation; nucleus,,3.00E-110,CHOYP_BRAFLDRAFT_120278.1.2,2.00E-27,ruditapes2_c3783,5.00E-109,BQ426475.p.cg.6,8,,PSF1_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; DNA strand elongation involved in mitotic DNA replication [GO:1902983]; inner cell mass cell proliferation [GO:0001833] comp108947_c0_seq1,211,44.0758,0.60400217,6,0,,,,,,,,,9.00E-15,CHOYP_ABCA1.3.3,,,,,,,,, comp108947_c1_seq1,807,44.114,0.4845967,38,36,,9.00E-59,Q9BZC7,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0043190; GO:0042626; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0006629; GO:0005765; GO:0005764; GO:0005815; GO:0032383; GO:0006357; GO:0042493; GO:0048545,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lipid metabolic process; lysosomal membrane; lysosome; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus",PF00005;,2.00E-25,CHOYP_ABCA1.1.3,,,,,,,ABCA2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp108948_c0_seq1,521,44.1459,0.55464685,26,0,,8.00E-35,A8MXQ7,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,,,,,,,,,,,,YH010_HUMAN,Homo sapiens (Human), comp108954_c0_seq1,1605,42.3676,0.50613251,13,17,,4.00E-88,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp108954_c1_seq1,384,44.0104,0.60431346,18,4,,6.00E-07,Q9UHN6,Transmembrane protein 2,Transmembrane protein 2,GO:0016021; GO:0007275,integral to membrane; multicellular organismal development,PF10162;,,,,,,,,,TMEM2_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp108954_c2_seq1,889,43.5321,0.50282549,51,7,,5.00E-28,P08F94,Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),GO:0031362; GO:0016324; GO:0016337; GO:0005813; GO:0042384; GO:0005737; GO:0042592; GO:0016021; GO:0001822; GO:0005932; GO:0072686; GO:0051271; GO:0072372; GO:0004872; GO:0010824,anchored to external side of plasma membrane; apical plasma membrane; cell-cell adhesion; centrosome; cilium assembly; cytoplasm; homeostatic process; integral to membrane; kidney development; microtubule basal body; mitotic spindle; negative regulation of cellular component movement; primary cilium; receptor activity; regulation of centrosome duplication,PF10162;PF01833;,,,,,,,,,PKHD1_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337] comp108972_c0_seq1,624,41.1859,0.58258912,16,13,,1.00E-84,O14807,Ras-related protein M-Ras (Ras-related protein R-Ras3),Ras-related protein M-Ras (Ras-related protein R-Ras3),GO:0005525; GO:0003924; GO:0007265; GO:0030036; GO:0007517; GO:0005886,GTP binding; GTPase activity; Ras protein signal transduction; actin cytoskeleton organization; muscle organ development; plasma membrane,PF00071;,6.00E-74,CHOYP_LOC100748982.1.1,,,,,,,RASM_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; Ras protein signal transduction [GO:0007265] comp109000_c0_seq3,278,41.3669,0.42923632,0,0,,6.00E-18,Q5D1D6,Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1),Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1),GO:0005525; GO:0006184; GO:0003924; GO:0000139; GO:0042742; GO:0051607; GO:0005576,GTP binding; GTP catabolic process; GTPase activity; Golgi membrane; defense response to bacterium; defense response to virus; extracellular region,PF02263;PF02841;,,,,,,,,,GBP1_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607] comp109010_c2_seq1,209,37.3206,0.41667621,3,19,,5.00E-25,Q9NQQ7,Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein),Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein),GO:0005801; GO:0005793; GO:0016021; GO:0010629; GO:0045747; GO:0036066; GO:0006810,cis-Golgi network; endoplasmic reticulum-Golgi intermediate compartment; integral to membrane; negative regulation of gene expression; positive regulation of Notch signaling pathway; protein O-linked fucosylation; transport,PF03151;,2.00E-28,CHOYP_S35C2.1.1,,,,,,,S35C2_HUMAN,Homo sapiens (Human),negative regulation of gene expression [GO:0010629]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked fucosylation [GO:0036066]; UDP-glucose transport [GO:0015786] comp109016_c0_seq1,378,39.9471,0.46560522,0,68,,4.00E-27,Q2NL00,Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),GO:0005737; GO:0004364,cytoplasm; glutathione transferase activity,PF00043;PF02798;,2.00E-14,CHOYP_LOC100166353.1.1,,,,,,,GSTT1_BOVIN,Bos taurus (Bovine),glutathione metabolic process [GO:0006749] comp109032_c0_seq1,360,45.2778,0.79732182,0,0,,2.00E-19,Q95JD5,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-),GO:0004062; GO:0005737; GO:0009812; GO:0008202; GO:0051923; GO:0042403; GO:0006805,aryl sulfotransferase activity; cytoplasm; flavonoid metabolic process; steroid metabolic process; sulfation; thyroid hormone metabolic process; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1B1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp109032_c0_seq2,335,44.7761,0.73203267,0,11,,1.00E-07,Q8RUC1,Cytosolic sulfotransferase 4 (AtSOT4) (EC 2.8.2.-),Cytosolic sulfotransferase 4 (AtSOT4) (EC 2.8.2.-),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,,,,,,,,,SOT4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp109032_c1_seq1,258,42.2481,1.13598198,3,35,,5.00E-09,P63047,Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),GO:0005737; GO:0008202; GO:0008146; GO:0006790,cytoplasm; steroid metabolic process; sulfotransferase activity; sulfur compound metabolic process,PF00685;,,,,,,,,,ST4A1_RAT,Rattus norvegicus (Rat),steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790] comp109075_c0_seq1,585,38.2906,0.24482023,22,19,,6.00E-35,Q5PQ63,Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein),Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein),GO:0016021; GO:0005743; GO:0006508; GO:0008236,integral to membrane; mitochondrial inner membrane; proteolysis; serine-type peptidase activity,PF00717;,,,,,,,,,IMP2L_XENLA,Xenopus laevis (African clawed frog), comp109089_c0_seq1,1262,35.6577,0.47585744,24,96,,9.00E-11,Q99675,Cell growth regulator with RING finger domain protein 1 (Cell growth regulatory gene 19 protein) (RING finger protein 197),Cell growth regulator with RING finger domain protein 1 (Cell growth regulatory gene 19 protein) (RING finger protein 197),GO:0007050; GO:0008285; GO:0005634; GO:0006950; GO:0008270,cell cycle arrest; negative regulation of cell proliferation; nucleus; response to stress; zinc ion binding,,,,,,,,,,CGRF1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; response to stress [GO:0006950] comp109090_c0_seq1,1159,35.3753,0.47422121,24,332,,2.00E-70,A8WGS4,TLC domain-containing protein 2,TLC domain-containing protein 2,GO:0016021,integral to membrane,PF03798;,5.00E-27,CHOYP_TLCD2.1.1,,,,,,,TLCD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp109093_c0_seq1,253,37.5494,0.22518082,4,9,,2.00E-06,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp109093_c0_seq2,253,37.9447,0.2205853,13,7,,2.00E-09,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp109099_c1_seq1,512,46.6797,0.50492319,6,27,,2.00E-92,Q62717,Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS),Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS),GO:0005509; GO:0030054; GO:0030659; GO:0005543; GO:0045956; GO:0015031; GO:0045055; GO:0045202,calcium ion binding; cell junction; cytoplasmic vesicle membrane; phospholipid binding; positive regulation of calcium ion-dependent exocytosis; protein transport; regulated secretory pathway; synapse,PF06292;PF00169;,2.00E-110,CHOYP_LOC100372028.1.1,,,,,,,CAPS1_RAT,Rattus norvegicus (Rat),dense core granule exocytosis [GO:1990504]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; synaptic vesicle exocytosis [GO:0016079] comp109105_c1_seq1,221,38.4615,0.90561295,0,13,,3.00E-08,Q8MJC3,Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],GO:0006915; GO:0004197; GO:0005737; GO:0006508,apoptotic process; cysteine-type endopeptidase activity; cytoplasm; proteolysis,,,,,,,,,,CASP3_RABIT,Oryctolagus cuniculus (Rabbit),apoptotic process [GO:0006915] comp109119_c2_seq1,639,45.2269,0.95274916,11,62,,1.00E-34,O73853,"Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.99.9) (EC 4.1.2.30) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17)","Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 4.1.2.30) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17)",GO:0047442; GO:0020037; GO:0005506; GO:0016020; GO:0004508; GO:0006694,17-alpha-hydroxyprogesterone aldolase activity; heme binding; iron ion binding; membrane; steroid 17-alpha-monooxygenase activity; steroid biosynthetic process,PF00067;,,,,,,,,,CP17A_ICTPU,Ictalurus punctatus (Channel catfish) (Silurus punctatus),sex differentiation [GO:0007548]; steroid biosynthetic process [GO:0006694] comp109128_c0_seq1,259,59.4595,1.14094528,0,15,,4.00E-34,P66952,Probable thiol peroxidase (EC 1.11.1.-),,GO:0045454; GO:0005618; GO:0005829; GO:0015036; GO:0052060; GO:0005576; GO:0009405; GO:0004601; GO:0051920; GO:0051409; GO:0006979; GO:0008379,cell redox homeostasis; cell wall; cytosol; disulfide oxidoreductase activity; evasion or tolerance by symbiont of host-produced nitric oxide; extracellular region; pathogenesis; peroxidase activity; peroxiredoxin activity; response to nitrosative stress; response to oxidative stress; thioredoxin peroxidase activity,,,,,,,,,,TPX_MYCTU,, comp109129_c0_seq1,332,42.7711,0.15445409,7,37,,2.00E-23,Q8BVI4,Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase),Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase),GO:0004155; GO:0006559; GO:0070404; GO:0070402; GO:0035690; GO:0005829; GO:0001889; GO:0005739; GO:0043005; GO:0010044; GO:0033762; GO:0010288; GO:0006729,"6,7-dihydropteridine reductase activity; L-phenylalanine catabolic process; NADH binding; NADPH binding; cellular response to drug; cytosol; liver development; mitochondrion; neuron projection; response to aluminum ion; response to glucagon stimulus; response to lead ion; tetrahydrobiopterin biosynthetic process",PF00106;,,,,,,,,,DHPR_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; liver development [GO:0001889]; L-phenylalanine catabolic process [GO:0006559]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729] comp109129_c1_seq1,340,39.1176,0.38820919,23,29,,,,,,,,,,,2.00E-29,ruditapes_c648,,,,,,, comp109134_c0_seq2,602,36.2126,0.46337218,3,0,,4.00E-43,Q86Y37,CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin1),CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin1),GO:0000082; GO:0031461; GO:0008284; GO:0045860; GO:0006511,G1/S transition of mitotic cell cycle; cullin-RING ubiquitin ligase complex; positive regulation of cell proliferation; positive regulation of protein kinase activity; ubiquitin-dependent protein catabolic process,PF00888;,7.00E-41,CHOYP_CACUL1.1.1,,,,,,,CACL1_HUMAN,Homo sapiens (Human),G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of cell proliferation [GO:0008284]; positive regulation of protein kinase activity [GO:0045860]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp109155_c0_seq1,953,44.0714,0.33079858,59,73,,2.00E-80,Q9NVI1,Fanconi anemia group I protein (Protein FACI),Fanconi anemia group I protein (Protein FACI),GO:0003677; GO:0006281; GO:0007049; GO:0005654; GO:0005886; GO:0031398,DNA binding; DNA repair; cell cycle; nucleoplasm; plasma membrane; positive regulation of protein ubiquitination,PF14679;PF14680;PF14675;PF14674;PF14676;PF14677;PF14678;,9.00E-23,CHOYP_FANCI.1.1,,,,,,,FANCI_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; mitotic G2 DNA damage checkpoint [GO:0007095]; positive regulation of protein ubiquitination [GO:0031398] comp109157_c0_seq1,814,43.8575,0.51274063,33,25,,1.00E-63,Q8BGG7,Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2),Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2),GO:0005737; GO:0090331; GO:0006469; GO:0005634; GO:0035335; GO:0004725; GO:0051279,cytoplasm; negative regulation of platelet aggregation; negative regulation of protein kinase activity; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; regulation of release of sequestered calcium ion into cytosol,PF00300;PF14604;PF00627;,,,,,,,,,UBS3B_MOUSE,Mus musculus (Mouse),negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of signal transduction [GO:0009968]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of osteoclast differentiation [GO:0045670]; regulation of release of sequestered calcium ion into cytosol [GO:0051279] comp109166_c0_seq1,626,46.6454,0.56016506,24,57,,3.00E-51,Q5VV43,Dyslexia-associated protein KIAA0319,Dyslexia-associated protein KIAA0319,GO:0005769; GO:0031901; GO:0016021; GO:2000171; GO:0001764; GO:0005886,early endosome; early endosome membrane; integral to membrane; negative regulation of dendrite development; neuron migration; plasma membrane,PF02010;,,,,,,,,,K0319_HUMAN,Homo sapiens (Human),negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764] comp109166_c1_seq2,388,47.4227,0.50561603,6,6,,1.00E-11,Q86VZ4,Low-density lipoprotein receptor-related protein 11 (LRP-11),Low-density lipoprotein receptor-related protein 11 (LRP-11),GO:0016021,integral to membrane,PF00057;PF07502;,1.00E-17,CHOYP_LOC100374794.1.1,,,,,,,LRP11_HUMAN,Homo sapiens (Human),multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414] comp109177_c1_seq1,542,42.4354,0.36997628,21,4,,1.00E-21,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,,,,,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp109181_c1_seq1,623,32.9053,0.60150531,10,52,,8.00E-40,Q147U1,Zinc finger protein 846,Zinc finger protein 846,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN846_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109186_c2_seq1,250,61.2,1.28808082,0,6,,4.00E-25,Q9RDE2,Tricorn protease homolog 1 (EC 3.4.21.-),Tricorn protease homolog 1 (EC 3.4.21.-),GO:0005737; GO:0006508; GO:0008236,cytoplasm; proteolysis; serine-type peptidase activity,PF07676;PF03572;PF14684;PF14685;,,,,,,,,,TRI1_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),proteolysis [GO:0006508] comp109192_c0_seq1,302,46.6887,0.99345352,4,23,,2.00E-40,Q7TPH6,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0042177; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; negative regulation of protein catabolic process; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,7.00E-12,CHOYP_MYCB2.1.2,,,,,,,MYCB2_MOUSE,Mus musculus (Mouse),"branchiomotor neuron axon guidance [GO:0021785]; cell morphogenesis involved in neuron differentiation [GO:0048667]; central nervous system projection neuron axonogenesis [GO:0021952]; motor neuron axon guidance [GO:0008045]; negative regulation of protein catabolic process [GO:0042177]; protein ubiquitination [GO:0016567]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109200_c0_seq2,547,40.4022,0.35940438,6,44,,8.00E-12,Q9ULM3,YEATS domain-containing protein 2,YEATS domain-containing protein 2,GO:0005671; GO:0043966; GO:0072686; GO:0000122,Ada2/Gcn5/Ada3 transcription activator complex; histone H3 acetylation; mitotic spindle; negative regulation of transcription from RNA polymerase II promoter,PF03366;,,,,,,,,,YETS2_HUMAN,Homo sapiens (Human),"histone H3 acetylation [GO:0043966]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]" comp109208_c0_seq3,667,40.7796,0.36834933,0,0,,1.00E-22,Q8CHS8,Vacuolar protein sorting-associated protein 37A (Vps37A) (ESCRT-I complex subunit VPS37A),Vacuolar protein sorting-associated protein 37A (Vps37A) (ESCRT-I complex subunit VPS37A),GO:0000813; GO:0031902; GO:0005634; GO:0015031; GO:0043162,ESCRT I complex; late endosome membrane; nucleus; protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF07200;,,,,,,,,,VP37A_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp109220_c1_seq2,650,40.1538,0.5031522,5,13,,,,,,,,,2.00E-42,CHOYP_LOC100167728.1.2,,,,,,,,, comp109220_c4_seq1,502,41.2351,0.65862588,10,19,,2.00E-56,Q6P3S1,DENN domain-containing protein 1B (Connecdenn 2) (Protein FAM31B),DENN domain-containing protein 1B (Connecdenn 2) (Protein FAM31B),GO:0017112; GO:0030136; GO:0005829; GO:0015031,Rab guanyl-nucleotide exchange factor activity; clathrin-coated vesicle; cytosol; protein transport,PF03455;PF02141;PF03456;,6.00E-47,CHOYP_LOC100167728.2.2,,,,,,,DEN1B_HUMAN,Homo sapiens (Human),endocytic recycling [GO:0032456]; protein transport [GO:0015031]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]; T-helper 2 cell cytokine production [GO:0035745] comp109225_c0_seq1,760,43.2895,0.69582565,30,9,,7.00E-119,P23098,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,8.00E-124,CHOYP_DYHC.1.3,,,,,,,DYHC_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp109233_c0_seq1,355,43.9437,0.35959881,29,60,,,,,,,,,1.00E-34,CHOYP_RBM19.1.2,,,,,,,,, comp109233_c1_seq1,321,43.3022,0.61686422,9,10,,5.00E-34,Q8R3C6,Probable RNA-binding protein 19 (RNA-binding motif protein 19),Probable RNA-binding protein 19 (RNA-binding motif protein 19),GO:0003723; GO:0005694; GO:0005737; GO:0007275; GO:0005730; GO:0005654; GO:0000166; GO:0040019,RNA binding; chromosome; cytoplasm; multicellular organismal development; nucleolus; nucleoplasm; nucleotide binding; positive regulation of embryonic development,PF00076;,,,,,,,,,RBM19_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019] comp109234_c0_seq1,863,38.8181,0.58741938,47,78,,2.00E-13,P53355,Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),GO:0005524; GO:0015629; GO:0097190; GO:0005516; GO:0004683; GO:0071346; GO:0005737; GO:0007243; GO:0043066; GO:0017148; GO:0043065; GO:0046777; GO:2000310; GO:0010506,ATP binding; actin cytoskeleton; apoptotic signaling pathway; calmodulin binding; calmodulin-dependent protein kinase activity; cellular response to interferon-gamma; cytoplasm; intracellular protein kinase cascade; negative regulation of apoptotic process; negative regulation of translation; positive regulation of apoptotic process; protein autophosphorylation; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of autophagy,PF12796;PF00531;PF00069;,,,,,,,,,DAPK1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310] comp109236_c1_seq1,514,37.5486,0.16830129,6,7,,1.00E-08,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109238_c0_seq1,647,38.0216,0.17142898,14,47,,7.00E-33,Q0IIE2,SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1),SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1),GO:0001525; GO:0005737; GO:0035556; GO:0040008,angiogenesis; cytoplasm; intracellular signal transduction; regulation of growth,PF00640;PF00017;,,,,,,,,,SHC1_BOVIN,Bos taurus (Bovine),activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; cellular response to growth factor stimulus [GO:0071363]; epidermal growth factor receptor signaling pathway [GO:0007173]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; regulation of growth [GO:0040008] comp109254_c2_seq1,260,43.0769,0.24968482,3,8,,2.00E-08,Q7XA72,ABC transporter G family member 21 (ABC transporter ABCG.21) (AtABCG21) (White-brown complex homolog protein 21) (AtWBC21),ABC transporter G family member 21 (ABC transporter ABCG.21) (AtABCG21) (White-brown complex homolog protein 21) (AtWBC21),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF01061;PF00005;,,,,,,,,,AB21G_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp109255_c0_seq1,494,45.3441,0.75706661,3,40,,3.00E-22,P18433,Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),GO:0007411; GO:0008286; GO:0005887; GO:0006468; GO:0005001,axon guidance; insulin receptor signaling pathway; integral to plasma membrane; protein phosphorylation; transmembrane receptor protein tyrosine phosphatase activity,PF00102;,2.00E-16,CHOYP_PTPRM.1.15,1.00E-14,ruditapes_c19189,,,,,PTPRA_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165] comp109256_c0_seq1,1190,38.2353,0.69147196,25,147,,4.00E-50,Q1RMT8,Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1),Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1),GO:0005524; GO:0001816; GO:0019221; GO:0005737; GO:0045087; GO:0000287; GO:0004674,ATP binding; cytokine production; cytokine-mediated signaling pathway; cytoplasm; innate immune response; magnesium ion binding; protein serine/threonine kinase activity,PF07714;,2.00E-12,CHOYP_IRAK4.1.1,,,,,,,IRAK4_BOVIN,Bos taurus (Bovine),cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp109259_c0_seq1,943,48.8865,0.71073713,7888,233,,7.00E-21,P15870,Histone H1-delta,Histone H1-delta,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00538;,3.00E-47,CHOYP_LOC100635715.6.9,1.00E-51,ruditapes_c7529,,,,,H1D_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),nucleosome assembly [GO:0006334] comp109266_c0_seq1,378,38.6243,0.50019204,8,55,,4.00E-11,Q8N1G0,Zinc finger protein 687,Zinc finger protein 687,GO:0003677; GO:0046872; GO:0005730; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16622;,,,,,,,,,ZN687_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109267_c0_seq1,2039,34.2325,0.5719376,6858,129,,2.00E-83,P62255,"Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]","Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]",GO:0005524; GO:0070936; GO:0070534; GO:0006511; GO:0004842,ATP binding; protein K48-linked ubiquitination; protein K63-linked ubiquitination; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00179;,5.00E-81,CHOYP_LOC100691486.1.1,,,,,,,UB2G1_RAT,Rattus norvegicus (Rat),protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp109278_c0_seq1,274,29.562,0.1720924,167,314,,,,,,,,,,,5.00E-11,ruditapes_c8858,,,,,,, comp109298_c0_seq1,387,39.2765,0.60467936,17,5,,6.00E-18,Q5ZL16,WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B),WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B),GO:0000045; GO:0005737; GO:0080025; GO:0032266,"autophagic vacuole assembly; cytoplasm; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding",,,,1.00E-13,ruditapes_c9243,,,,,WIPI3_CHICK,Gallus gallus (Chicken),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497] comp109307_c0_seq1,359,48.468,0.5934112,14,3,,4.00E-08,Q5M8S2,Serine protease 46 (EC 3.4.21.-),Serine protease 46 (EC 3.4.21.-),GO:0016021; GO:0006508; GO:0004252,integral to membrane; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,PRS46_MOUSE,Mus musculus (Mouse), comp109309_c0_seq1,242,34.7107,0.8384272,593,1481,,,,,,,,,2.00E-16,CHOYP_TBA1.3.9,8.00E-14,ruditapes_c5648,,,,,,, comp109319_c0_seq1,379,35.0923,0.69406876,13,54,,5.00E-06,Q55GK8,Membrane-associated sulfotransferase kil1 (EC 2.8.2.-),Membrane-associated sulfotransferase kil1 (EC 2.8.2.-),GO:0042742; GO:0016021; GO:0006477; GO:0008146,defense response to bacterium; integral to membrane; protein sulfation; sulfotransferase activity,PF00685;,8.00E-19,CHOYP_HS3SB.1.2,,,,,,,KIL1_DICDI,Dictyostelium discoideum (Slime mold),defense response to bacterium [GO:0042742]; protein sulfation [GO:0006477] comp109319_c1_seq1,631,36.2916,0.82140879,20,35,,3.00E-65,Q9Y662,Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B),Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B),GO:0000139; GO:0008467; GO:0033872; GO:0005975; GO:0006024; GO:0015015; GO:0005887,"Golgi membrane; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity; carbohydrate metabolic process; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; integral to plasma membrane",PF00685;,,,,,,,,,HS3SB_HUMAN,Homo sapiens (Human),"glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" comp109344_c0_seq2,706,44.4759,0.40157497,10,7,,8.00E-123,Q6VNB8,"WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)","WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)",GO:0005545; GO:0005776; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; autophagic vacuole; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,1.00E-107,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_MOUSE,Mus musculus (Mouse),aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239] comp109366_c0_seq1,511,47.5538,0.56535758,29,9,,5.00E-50,Q9BX63,Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1),Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0000077; GO:0005737; GO:0006302; GO:0046872; GO:0031965; GO:0006357,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA damage checkpoint; cytoplasm; double-strand break repair; metal ion binding; nuclear membrane; regulation of transcription from RNA polymerase II promoter",PF06733;PF13307;,6.00E-28,CHOYP_FANCJ.1.1,,,,,,,FANCJ_HUMAN,Homo sapiens (Human),cellular response to vitamin [GO:0071295]; DNA damage checkpoint [GO:0000077]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; negative regulation of cell proliferation [GO:0008285]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; strand displacement [GO:0000732] comp109370_c0_seq1,1425,31.5789,0.53791049,3579,5666,,1.00E-25,Q9JKP8,Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (NF-YC-like protein) (YC-like protein 1) (YCL1),Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (NF-YC-like protein) (YC-like protein 1) (YCL1),GO:0003887; GO:0005634; GO:0043565,DNA-directed DNA polymerase activity; nucleus; sequence-specific DNA binding,PF00808;,1.00E-11,CHOYP_CHRC1.1.2,,,,,,,CHRC1_MOUSE,Mus musculus (Mouse),chromatin remodeling [GO:0006338] comp109377_c0_seq1,627,41.6268,0.82004007,28,12,,7.00E-97,Q9UPW8,Protein unc-13 homolog A (Munc13-1),Protein unc-13 homolog A (Munc13-1),GO:0050435; GO:0030054; GO:0005737; GO:0019992; GO:0060384; GO:0035556; GO:0046872; GO:0031594; GO:0007528; GO:0001956; GO:0042734; GO:0048172; GO:0035249; GO:0016081; GO:0016188; GO:0016082,"beta-amyloid metabolic process; cell junction; cytoplasm; diacylglycerol binding; innervation; intracellular signal transduction; metal ion binding; neuromuscular junction; neuromuscular junction development; positive regulation of neurotransmitter secretion; presynaptic membrane; regulation of short-term neuronal synaptic plasticity; synaptic transmission, glutamatergic; synaptic vesicle docking involved in exocytosis; synaptic vesicle maturation; synaptic vesicle priming",PF00130;PF00168;PF06292;PF10540;,9.00E-78,CHOYP_LOC100650524.1.2,,,,,,,UN13A_HUMAN,Homo sapiens (Human),"beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]" comp109394_c0_seq1,830,41.6867,0.58356826,10,57,,9.00E-10,O54963,RE1-silencing transcription factor (Neural-restrictive silencer factor),RE1-silencing transcription factor (Neural-restrictive silencer factor),GO:0001078; GO:0060379; GO:0035690; GO:0071257; GO:0071385; GO:0000785; GO:0003682; GO:0001047; GO:0070933; GO:0046872; GO:0043922; GO:0032348; GO:2000798; GO:0045955; GO:0008285; GO:2000065; GO:2000706; GO:0046676; GO:0050768; GO:0045665; GO:0015271; GO:0043065; GO:0043280; GO:0032403; GO:0017053,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cardiac muscle cell myoblast differentiation; cellular response to drug; cellular response to electrical stimulus; cellular response to glucocorticoid stimulus; chromatin; chromatin binding; core promoter binding; histone H4 deacetylation; metal ion binding; negative regulation by host of viral transcription; negative regulation of aldosterone biosynthetic process; negative regulation of amniotic stem cell differentiation; negative regulation of calcium ion-dependent exocytosis; negative regulation of cell proliferation; negative regulation of cortisol biosynthetic process; negative regulation of dense core granule biogenesis; negative regulation of insulin secretion; negative regulation of neurogenesis; negative regulation of neuron differentiation; outward rectifier potassium channel activity; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; protein complex binding; transcriptional repressor complex,,,,,,,,,,REST_RAT,Rattus norvegicus (Rat),"cardiac muscle cell myoblast differentiation [GO:0060379]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucocorticoid stimulus [GO:0071385]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of amniotic stem cell differentiation [GO:2000798]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of dense core granule biogenesis [GO:2000706]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; transcription, DNA-templated [GO:0006351]" comp109394_c1_seq1,314,43.949,0.72840764,3,43,,5.00E-09,Q8BI99,Zinc finger protein 879,Zinc finger protein 879,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN879_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109394_c5_seq1,405,43.9506,0.51360212,3,23,,4.00E-07,A2A884,Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3 homolog) (KB-binding and recognition component) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Recombinant component) (Schnurri-3) (Zinc finger protein ZAS3),Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3 homolog) (KB-binding and recognition component) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Recombinant component) (Schnurri-3) (Zinc finger protein ZAS3),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0045893; GO:0035914; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; skeletal muscle cell differentiation; transcription, DNA-dependent",,9.00E-25,CHOYP_XFIN.1.4,,,,,,,ZEP3_MOUSE,Mus musculus (Mouse),"positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366]" comp109398_c0_seq1,356,43.5393,0.41650329,7,11,,4.00E-38,Q58EM4,UPF0364 protein C6orf211 homolog,Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1),,,PF01937;,,,,,,,,,CF211_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),methylation [GO:0032259]; protein methylation [GO:0006479]; regulation of response to DNA damage stimulus [GO:2001020] comp109403_c0_seq1,466,45.7082,0.5034159,11,32,,3.00E-77,Q6NZM9,Histone deacetylase 4 (HD4) (EC 3.5.1.98),Histone deacetylase 4 (HD4) (EC 3.5.1.98),GO:0031672; GO:0003677; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0030018; GO:0042641; GO:0006338; GO:0005829; GO:0000118; GO:0008285; GO:0045820; GO:0010832; GO:0045668; GO:0043433; GO:0000122; GO:0031594; GO:0005634; GO:0002076; GO:0034983; GO:0008284; GO:0033235; GO:0051091; GO:0045944; GO:0030955; GO:0033558; GO:0010882; GO:0043393; GO:0048742; GO:0014894; GO:0042493; GO:0070555; GO:0043565; GO:0001501; GO:0003714; GO:0044212; GO:0006351; GO:0017053; GO:0008270,"A band; DNA binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); Z disc; actomyosin; chromatin remodeling; cytosol; histone deacetylase complex; negative regulation of cell proliferation; negative regulation of glycolysis; negative regulation of myotube differentiation; negative regulation of osteoblast differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; neuromuscular junction; nucleus; osteoblast development; peptidyl-lysine deacetylation; positive regulation of cell proliferation; positive regulation of protein sumoylation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; potassium ion binding; protein deacetylase activity; regulation of cardiac muscle contraction by calcium ion signaling; regulation of protein binding; regulation of skeletal muscle fiber development; response to denervation involved in regulation of muscle adaptation; response to drug; response to interleukin-1; sequence-specific DNA binding; skeletal system development; transcription corepressor activity; transcription regulatory region DNA binding; transcription, DNA-dependent; transcriptional repressor complex; zinc ion binding",PF12203;PF00850;,3.00E-50,CHOYP_ISCW_ISCW014481.1.1,,,,,,,HDAC4_MOUSE,Mus musculus (Mouse),"cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]" comp109426_c0_seq1,889,44.8819,1.1442487,252,7872,,3.00E-10,Q60648,Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),GO:0004563; GO:0008047; GO:0006689; GO:0007611; GO:0019915; GO:0005764; GO:0005739; GO:0050885; GO:0005730; GO:0009313,beta-N-acetylhexosaminidase activity; enzyme activator activity; ganglioside catabolic process; learning or memory; lipid storage; lysosome; mitochondrion; neuromuscular process controlling balance; nucleolus; oligosaccharide catabolic process,PF02221;,,,,,,,,,SAP3_MOUSE,Mus musculus (Mouse),ganglioside catabolic process [GO:0006689]; learning or memory [GO:0007611]; lipid storage [GO:0019915]; neurological system process [GO:0050877]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; positive regulation of hydrolase activity [GO:0051345] comp109436_c0_seq1,1307,43.6113,1.11422287,1327,11669,,7.00E-14,Q9QXV1,Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3),Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3),GO:0035102; GO:0006342; GO:0000792; GO:0016574; GO:0000122; GO:0000790; GO:0003727; GO:0006351; GO:0000151,"PRC1 complex; chromatin silencing; heterochromatin; histone ubiquitination; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; single-stranded RNA binding; transcription, DNA-dependent; ubiquitin ligase complex",PF00385;,3.00E-12,CHOYP_LOC100564588.1.1,5.00E-38,ruditapes_c20825,,,,,CBX8_MOUSE,Mus musculus (Mouse),"cellular response to hydrogen peroxide [GO:0070301]; chromatin silencing [GO:0006342]; histone ubiquitination [GO:0016574]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA repair [GO:0045739]; transcription, DNA-templated [GO:0006351]" comp109445_c0_seq1,552,47.6449,0.70806891,9,15,,3.00E-09,Q7TSU7,Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2),Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2),GO:0016337; GO:0016021; GO:0001933; GO:0005886; GO:0036057,cell-cell adhesion; integral to membrane; negative regulation of protein phosphorylation; plasma membrane; slit diaphragm,PF08205;PF07679;,,,,,,,,,KIRR2_MOUSE,Mus musculus (Mouse),negative regulation of protein phosphorylation [GO:0001933]; single organismal cell-cell adhesion [GO:0016337] comp109446_c0_seq1,575,43.6522,0.51206657,12,29,,7.00E-48,P17041,Zinc finger protein 32 (C2H2-546) (Zinc finger protein KOX30),Zinc finger protein 32 (C2H2-546) (Zinc finger protein KOX30),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZNF32_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109453_c0_seq1,222,75.6757,1.01495446,0,10,,1.00E-34,Q47F10,Phosphonates import ATP-binding protein PhnC (EC 3.6.3.28),Phosphonates import ATP-binding protein PhnC (EC 3.6.3.28),GO:0005524; GO:0006200; GO:0015416; GO:0005886,ATP binding; ATP catabolic process; organic phosphonate transmembrane-transporting ATPase activity; plasma membrane,PF00005;,,,,,,,,,PHNC_DECAR,Dechloromonas aromatica (strain RCB), comp109459_c0_seq1,667,39.2804,0.86138169,8,114,,3.00E-17,P34147,Rho-related protein racA,Rho-related protein racA,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00651;PF00071;,,,,,,,,,RACA_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp10945_c0_seq1,269,48.6989,0.37939634,6,0,,3.00E-08,O88572,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0090245; GO:0046849; GO:0060444; GO:0061310; GO:0061324; GO:0005901; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0060026; GO:0015026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0051593; GO:0048705; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; axis elongation involved in somitogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; caveola; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; convergent extension; coreceptor activity; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; response to folic acid; skeletal system morphogenesis; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,,,,,,,,,LRP6_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp109460_c0_seq1,265,44.1509,0.5489465,5,22,,7.00E-07,Q7Z3E1,TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7),TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7),GO:0003950; GO:0008209; GO:0008210; GO:0060325; GO:0008585; GO:0030097; GO:0001822; GO:0046872; GO:0044236; GO:0006807; GO:0060021; GO:0048008; GO:0009791; GO:0006471; GO:0048705; GO:0048745; GO:0001570,NAD+ ADP-ribosyltransferase activity; androgen metabolic process; estrogen metabolic process; face morphogenesis; female gonad development; hemopoiesis; kidney development; metal ion binding; multicellular organismal metabolic process; nitrogen compound metabolic process; palate development; platelet-derived growth factor receptor signaling pathway; post-embryonic development; protein ADP-ribosylation; skeletal system morphogenesis; smooth muscle tissue development; vasculogenesis,PF00644;,,,,,,,,,PARPT_HUMAN,Homo sapiens (Human),androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; multicellular organism metabolic process [GO:0044236]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; protein ADP-ribosylation [GO:0006471]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] comp109478_c0_seq1,1117,37.2426,0.70879178,10661,26466,,,,,,,,,,,2.00E-93,ruditapes2_c3888,,,,,,, comp109481_c1_seq1,867,41.6378,0.2147189,31,72,,5.00E-133,A4FV08,Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin),Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin),GO:0006044; GO:0005975; GO:0005737; GO:0006091; GO:0006043; GO:0004342; GO:0016787,N-acetylglucosamine metabolic process; carbohydrate metabolic process; cytoplasm; generation of precursor metabolites and energy; glucosamine catabolic process; glucosamine-6-phosphate deaminase activity; hydrolase activity,PF01182;,2.00E-100,CHOYP_GNPI2.1.1,,,,,,,GNPI1_BOVIN,Bos taurus (Bovine),carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp109483_c0_seq1,399,31.5789,0.20340835,5,0,,,,,,,,,2.00E-32,CHOYP_LOC100636931.6.8,,,,,,,,, comp109483_c0_seq2,565,32.0354,0.27711225,11,11,,,,,,,,,3.00E-19,CHOYP_LOC100636931.2.8,,,,,,,,, comp109484_c0_seq2,788,39.9746,0.33221106,19,18,,3.00E-07,P50748,Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),GO:0051301; GO:0000777; GO:0005829; GO:0005828; GO:0007067; GO:0000278; GO:0007093; GO:0005634; GO:0006461; GO:0007096; GO:0000922,cell division; condensed chromosome kinetochore; cytosol; kinetochore microtubule; mitosis; mitotic cell cycle; mitotic cell cycle checkpoint; nucleus; protein complex assembly; regulation of exit from mitosis; spindle pole,PF10493;,,,,,,,,,KNTC1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062] comp109505_c0_seq1,2563,29.8869,0.45204158,80660,1209,,1.00E-44,Q34947,NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5),NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5),GO:0042773; GO:0008137; GO:0016021; GO:0005743; GO:0070469,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; integral to membrane; mitochondrial inner membrane; respiratory chain,PF06455;PF00361;PF00662;,4.00E-14,CHOYP_ND5.5.6,3.00E-26,ruditapes_c11833,,,,,NU5M_LUMTE,Lumbricus terrestris (Common earthworm),ATP synthesis coupled electron transport [GO:0042773] comp109506_c0_seq1,476,44.1176,0.8223428,10,15,,1.00E-08,Q8N8X9,Protein mab-21-like 3,Protein mab-21-like 3,,,PF03281;,,,,,,,,,MB213_HUMAN,Homo sapiens (Human), comp109510_c0_seq3,517,39.0716,0.91412107,1,38,,1.00E-13,P58545,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,,,,,,,,,BTBD3_MOUSE,Mus musculus (Mouse),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813] comp109511_c0_seq1,896,37.2768,1.02937191,3172,58844,,5.00E-06,P33248,Thymosin beta-12,Thymosin beta-12,GO:0030036; GO:0005737; GO:0005856; GO:0042989,actin cytoskeleton organization; cytoplasm; cytoskeleton; sequestering of actin monomers,PF01290;,,,6.00E-35,ruditapes_lrc34108,,,,,TYB12_LATJA,Lateolabrax japonicus (Japanese sea perch) (Japanese sea bass),actin filament organization [GO:0007015] comp109512_c0_seq1,476,42.6471,0.65088007,14,12,,5.00E-28,P52846,Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol-sulfating phenol sulfotransferase) (P-PST),Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol-sulfating phenol sulfotransferase) (P-PST),GO:0004062; GO:0006584; GO:0005737; GO:0008202,aryl sulfotransferase activity; catecholamine metabolic process; cytoplasm; steroid metabolic process,PF00685;,,,,,,,,,ST1A1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202] comp109512_c1_seq1,287,37.9791,0.84396629,3,35,,2.00E-07,Q9M1V1,Cytosolic sulfotransferase 6 (AtSOT6) (EC 2.8.2.-) (sulfotransferase 3b) (AtST3b),Cytosolic sulfotransferase 6 (AtSOT6) (EC 2.8.2.-) (sulfotransferase 3b) (AtST3b),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,,,,,,,,,SOT6_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp109521_c0_seq1,397,48.1108,0.97964372,1,55,,8.00E-21,Q91754,Glucokinase regulatory protein (Glucokinase regulator),Glucokinase regulatory protein (Glucokinase regulator),GO:0030246; GO:0005975; GO:0005737; GO:0070095; GO:0033132; GO:0005654,carbohydrate binding; carbohydrate metabolic process; cytoplasm; fructose-6-phosphate binding; negative regulation of glucokinase activity; nucleoplasm,,3.00E-11,CHOYP_GCKR.1.1,,,,,,,GCKR_XENLA,Xenopus laevis (African clawed frog),carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132] comp109532_c0_seq1,1513,38.731,0.44969604,11221,42058,,4.00E-161,P12261,Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma),Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma),GO:0005853; GO:0003746,eukaryotic translation elongation factor 1 complex; translation elongation factor activity,PF00647;PF00043;PF02798;,2.00E-121,CHOYP_ABCF2.1.2,5.00E-159,ruditapes_c4025,,,,,EF1G_ARTSA,Artemia salina (Brine shrimp), comp109539_c0_seq1,653,35.6815,0.72991243,6509,17416,,3.00E-21,Q9CQ69,Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C),Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C),GO:0021680; GO:0021766; GO:0021854; GO:0030901; GO:0005743; GO:0021548; GO:0021860; GO:0070469; GO:0021539; GO:0021794; GO:0008121,cerebellar Purkinje cell layer development; hippocampus development; hypothalamus development; midbrain development; mitochondrial inner membrane; pons development; pyramidal neuron development; respiratory chain; subthalamus development; thalamus development; ubiquinol-cytochrome-c reductase activity,PF02939;,,,,,,,,,QCR8_MOUSE,Mus musculus (Mouse),cerebellar Purkinje cell layer development [GO:0021680]; hippocampus development [GO:0021766]; hypothalamus development [GO:0021854]; midbrain development [GO:0030901]; pons development [GO:0021548]; pyramidal neuron development [GO:0021860]; subthalamus development [GO:0021539]; thalamus development [GO:0021794] comp109543_c0_seq1,577,37.6083,0.85967012,40630,87491,,6.00E-81,Q6XIM8,40S ribosomal protein S15a,40S ribosomal protein S15a,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00410;,1.00E-88,CHOYP_RS15A.4.11,8.00E-120,ruditapes2_c203,,,,,RS15A_DROYA,Drosophila yakuba (Fruit fly),translation [GO:0006412] comp109547_c0_seq1,1742,42.7669,0.71142881,1165,6408,,3.00E-41,P07909,Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),GO:0036099; GO:0048027; GO:0033119; GO:0000166; GO:0005634; GO:0048477; GO:0005703; GO:0045727; GO:0000381; GO:0030529; GO:0043565,"female germ-line stem cell maintenance; mRNA 5'-UTR binding; negative regulation of RNA splicing; nucleotide binding; nucleus; oogenesis; polytene chromosome puff; positive regulation of translation; regulation of alternative mRNA splicing, via spliceosome; ribonucleoprotein complex; sequence-specific DNA binding",PF00076;,2.00E-15,CHOYP_MMEL1.3.3,3.00E-17,ruditapes_lrc32974,,,,,ROA1_DROME,Drosophila melanogaster (Fruit fly),"compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]" comp109547_c0_seq2,1754,42.7594,0.70511934,4754,24955,,9.00E-41,P48810,Heterogeneous nuclear ribonucleoprotein 87F (HRP36.1 protein) (Protein P11),Heterogeneous nuclear ribonucleoprotein 87F (HRP36.1 protein) (Protein P11),GO:0000785; GO:0005737; GO:0008585; GO:0003729; GO:0007067; GO:0022008; GO:0000166; GO:0035062; GO:0005703; GO:0000381; GO:0009408; GO:0042594; GO:0030529; GO:0043565,"chromatin; cytoplasm; female gonad development; mRNA binding; mitosis; neurogenesis; nucleotide binding; omega speckle; polytene chromosome puff; regulation of alternative mRNA splicing, via spliceosome; response to heat; response to starvation; ribonucleoprotein complex; sequence-specific DNA binding",PF00076;,1.00E-17,CHOYP_LOC100748395.7.7,1.00E-10,ruditapes_lrc33717,,,,,RB87F_DROME,Drosophila melanogaster (Fruit fly),"compound eye morphogenesis [GO:0001745]; female gonad development [GO:0008585]; mitotic nuclear division [GO:0007067]; neurogenesis [GO:0022008]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to heat [GO:0009408]; response to starvation [GO:0042594]" comp109549_c0_seq1,567,41.7989,0.97288341,40230,93041,,3.00E-86,Q86FP7,40S ribosomal protein S23,40S ribosomal protein S23,GO:0015935; GO:0003735; GO:0006412,small ribosomal subunit; structural constituent of ribosome; translation,PF00164;,3.00E-121,CHOYP_RS23.1.9,6.00E-134,ruditapes2_c142,,,,,RS23_DERVA,Dermacentor variabilis (American dog tick),translation [GO:0006412] comp109550_c0_seq1,1070,38.972,0.54237882,43993,91962,,2.00E-90,Q8ISP0,40S ribosomal protein S18,40S ribosomal protein S18,GO:0019843; GO:0005840; GO:0003735; GO:0006412,rRNA binding; ribosome; structural constituent of ribosome; translation,PF00416;,3.00E-124,CHOYP_RS18.1.11,3.00E-147,ruditapes_lrc33732,,,,,RS18_BRABE,Branchiostoma belcheri (Amphioxus),translation [GO:0006412] comp109555_c0_seq1,265,47.1698,0.55273514,10,0,,5.00E-24,A0JM08,Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B),Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B),GO:0005737; GO:0005874,cytoplasm; microtubule,PF15308;PF00498;,4.00E-27,CHOYP_SRAP.10.18,,,,,,,K0284_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp109558_c0_seq1,1769,43.5839,0.51652545,255371,1175155,,0,Q9YIC0,Elongation factor 1-alpha (EF-1-alpha),Elongation factor 1-alpha (EF-1-alpha),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,0,CHOYP_EF1A.2.4,0,ruditapes2_c1,,,,,EF1A_ORYLA,Oryzias latipes (Japanese rice fish) (Japanese killifish), comp109560_c0_seq1,450,41.7778,0.46067643,111121,175589,,1.00E-40,Q8ISN9,40S ribosomal protein S25,40S ribosomal protein S25,GO:0005840,ribosome,PF03297;,2.00E-66,CHOYP_LOC101157312.1.1,5.00E-83,ruditapes2_c1360,,,,,RS25_BRABE,Branchiostoma belcheri (Amphioxus), comp109561_c0_seq1,559,42.7549,0.71036168,74547,186190,,3.00E-27,P08570,60S acidic ribosomal protein P1 (Acidic ribosomal protein RPA2) (RP21C),60S acidic ribosomal protein P1 (Acidic ribosomal protein RPA2) (RP21C),GO:0005840; GO:0003735; GO:0006414,ribosome; structural constituent of ribosome; translational elongation,,7.00E-53,CHOYP_RLA1.5.12,9.00E-94,ruditapes2_c4099,,,,,RLA1_DROME,Drosophila melanogaster (Fruit fly),cytoplasmic translation [GO:0002181]; positive regulation of protein kinase activity [GO:0045860]; translational elongation [GO:0006414] comp109562_c0_seq1,516,42.6357,0.5610673,72147,134408,,3.00E-69,P48159,60S ribosomal protein L23 (L17A),60S ribosomal protein L23 (L17A),GO:0000022; GO:0022008; GO:0005840; GO:0003735; GO:0006412,mitotic spindle elongation; neurogenesis; ribosome; structural constituent of ribosome; translation,PF00238;,8.00E-122,CHOYP_BRAFLDRAFT_73285.2.2,5.00E-128,ruditapes_lrc33777,,,,,RL23_DROME,Drosophila melanogaster (Fruit fly),mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; neurogenesis [GO:0022008]; translation [GO:0006412] comp109565_c0_seq1,987,42.6545,0.53886066,49987,260303,,2.00E-153,P49395,40S ribosomal protein S3a (Lysine-rich protein KRP-A),40S ribosomal protein S3a (Lysine-rich protein KRP-A),GO:0022627; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; structural constituent of ribosome; translation,PF01015;,0,CHOYP_RS3A.14.15,0,ruditapes2_c4755,,,,,RS3A_APLCA,Aplysia californica (California sea hare),translation [GO:0006412] comp109566_c0_seq1,675,42.963,0.57942984,39023,158574,,1.00E-89,Q02543,60S ribosomal protein L18a,60S ribosomal protein L18a,GO:0003723; GO:0006614; GO:0022625; GO:0000184; GO:0003735; GO:0006414; GO:0006413; GO:0006415; GO:0019083,"RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosolic large ribosomal subunit; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; structural constituent of ribosome; translational elongation; translational initiation; translational termination; viral transcription",PF01775;,4.00E-83,CHOYP_RL18A.1.8,1.00E-144,ruditapes_lrc32108,,,,,RL18A_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]" comp109568_c0_seq1,418,40.9091,0.63223956,23034,73531,,7.00E-38,O61462,60S ribosomal protein L37a,60S ribosomal protein L37a,GO:0046872; GO:0005840; GO:0003735; GO:0006412,metal ion binding; ribosome; structural constituent of ribosome; translation,PF01780;,8.00E-51,CHOYP_RL37A.2.7,1.00E-78,ruditapes2_c468,,,,,RL37A_CRYST,Cryptochiton stelleri (Giant gumboot chiton),translation [GO:0006412] comp109569_c0_seq1,538,43.3086,0.64062025,51454,116532,,3.00E-64,P31674,40S ribosomal protein S15,40S ribosomal protein S15,GO:0003723; GO:0015935; GO:0003735; GO:0006412,RNA binding; small ribosomal subunit; structural constituent of ribosome; translation,PF00203;,5.00E-80,CHOYP_ISCW_ISCW016148.4.6,2.00E-134,ruditapes_lrc33878,,,,,RS15_ORYSJ,Oryza sativa subsp. japonica (Rice),ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] comp109571_c0_seq1,576,45.1389,0.51407853,34535,124593,,5.00E-76,Q9W237,40S ribosomal protein S16,40S ribosomal protein S16,GO:0000022; GO:0005840; GO:0003735; GO:0006412,mitotic spindle elongation; ribosome; structural constituent of ribosome; translation,PF00380;,3.00E-90,CHOYP_RS16.4.5,3.00E-113,ruditapes_lrc33912,,,,,RS16_DROME,Drosophila melanogaster (Fruit fly),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; translation [GO:0006412]" comp109572_c0_seq1,437,38.6728,0.55365458,34913,72814,,3.00E-43,P27075,60S ribosomal protein L44 (60S ribosomal protein L41),60S ribosomal protein L44 (60S ribosomal protein L41),GO:0046677; GO:0046898; GO:0005840; GO:0003735; GO:0006412,response to antibiotic; response to cycloheximide; ribosome; structural constituent of ribosome; translation,PF00935;,3.00E-56,CHOYP_BRAFLDRAFT_104488.1.3,2.00E-88,ruditapes2_c255,,,,,RL44_CANTR,Candida tropicalis (Yeast),response to antibiotic [GO:0046677]; response to cycloheximide [GO:0046898]; translation [GO:0006412] comp109573_c0_seq1,931,42.5349,0.40874077,41411,101719,,3.00E-82,Q94613,40S ribosomal protein S19,40S ribosomal protein S19,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01090;,2.00E-50,CHOYP_RS19.3.12,2.00E-92,ruditapes_lrc34645,,,,,RS19_MYAAR,Mya arenaria (Soft-shell clam),translation [GO:0006412] comp109581_c0_seq1,495,44.6465,0.56880966,13,26,,6.00E-12,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp109584_c1_seq1,762,40.4199,0.390282,33,82,,2.00E-54,Q8BVF7,Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha),Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha),GO:0005794; GO:0007220; GO:0007219; GO:0042987; GO:0004175; GO:0005783; GO:0005789; GO:0005887; GO:0006509; GO:0031293; GO:0001656; GO:0043085; GO:0016485,Golgi apparatus; Notch receptor processing; Notch signaling pathway; amyloid precursor protein catabolic process; endopeptidase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; metanephros development; positive regulation of catalytic activity; protein processing,PF06105;,,,,,,,,,APH1A_MOUSE,Mus musculus (Mouse),amyloid precursor protein catabolic process [GO:0042987]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; metanephros development [GO:0001656]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485] comp109600_c0_seq1,585,43.0769,1.04297279,17,72,,7.00E-40,B3A0Q8,Peroxidase-like protein 3 (Fragment),Peroxidase-like protein 3 (Fragment),GO:0005576; GO:0020037; GO:0004601; GO:0006979,extracellular region; heme binding; peroxidase activity; response to oxidative stress,PF03098;,,,,,,,,,PLSP2_LOTGI,Lottia gigantea (Giant owl limpet),response to oxidative stress [GO:0006979] comp109602_c0_seq1,938,40.2985,0.82412823,54,89,,3.00E-15,Q2VPM4,Zinc finger protein 703-B,Zinc finger protein 703-B,GO:0034333; GO:0005737; GO:0046872; GO:0034111; GO:0045892; GO:0003676; GO:0005634; GO:0030335; GO:0060828; GO:0051726; GO:0017015; GO:0006351,"adherens junction assembly; cytoplasm; metal ion binding; negative regulation of homotypic cell-cell adhesion; negative regulation of transcription, DNA-dependent; nucleic acid binding; nucleus; positive regulation of cell migration; regulation of canonical Wnt receptor signaling pathway; regulation of cell cycle; regulation of transforming growth factor beta receptor signaling pathway; transcription, DNA-dependent",PF12402;,2.00E-11,CHOYP_ZN703.1.1,6.00E-48,ruditapes2_c1606,,,,,Z703B_XENLA,Xenopus laevis (African clawed frog),"adherens junction assembly [GO:0034333]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell migration [GO:0030335]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]" comp109604_c0_seq1,1607,38.5812,0.76973057,8875,25940,,6.00E-15,Q9GPH3,Activating transcription factor of chaperone,Activating transcription factor of chaperone,GO:0005634; GO:0006986; GO:0043565; GO:0003700; GO:0006351,"nucleus; response to unfolded protein; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00170;,,,7.00E-25,ruditapes_lrc32605,,,,,ATFC_BOMMO,Bombyx mori (Silk moth),"response to unfolded protein [GO:0006986]; transcription, DNA-templated [GO:0006351]" comp109629_c0_seq2,917,45.3653,0.57422921,0,9,,1.00E-27,P18887,DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1),DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1),GO:0006284; GO:0003684; GO:0021766; GO:0005654; GO:0042493; GO:0001666; GO:0010033; GO:0000012,base-excision repair; damaged DNA binding; hippocampus development; nucleoplasm; response to drug; response to hypoxia; response to organic substance; single strand break repair,PF00533;PF16589;PF01834;,,,,,,,,,XRCC1_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp109633_c0_seq1,436,40.367,0.40128769,17,7,,2.00E-17,A2VDL9,Transmembrane protein 184B,Transmembrane protein 184B,GO:0016021,integral to membrane,PF03619;,1.00E-17,CHOYP_T184B.1.1,,,,,,,T184B_BOVIN,Bos taurus (Bovine),transport [GO:0006810] comp109637_c0_seq1,656,36.4329,0.64466088,9,84,,1.00E-30,Q86V85,Integral membrane protein GPR180 (Intimal thickness-related receptor),Integral membrane protein GPR180 (Intimal thickness-related receptor),GO:0007186; GO:0016021; GO:0019236,G-protein coupled receptor signaling pathway; integral to membrane; response to pheromone,PF10192;,3.00E-33,CHOYP_BRAFLDRAFT_244305.1.1,1.00E-22,ruditapes_c24962,,,,,GP180_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] comp109639_c0_seq1,797,41.4053,0.45575765,26,66,,7.00E-69,Q9Y4C8,Probable RNA-binding protein 19 (RNA-binding motif protein 19),Probable RNA-binding protein 19 (RNA-binding motif protein 19),GO:0003723; GO:0005694; GO:0005737; GO:0007275; GO:0005730; GO:0005654; GO:0000166; GO:0040019,RNA binding; chromosome; cytoplasm; multicellular organismal development; nucleolus; nucleoplasm; nucleotide binding; positive regulation of embryonic development,PF00076;,5.00E-63,CHOYP_RBM19.1.2,,,,,,,RBM19_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019] comp109645_c0_seq1,270,37.7778,0.83643123,13,0,,2.00E-06,P31721,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit B,GO:0007568; GO:0007420; GO:0005581; GO:0006958; GO:0005602; GO:0006955; GO:0045087; GO:0051384,"aging; brain development; collagen; complement activation, classical pathway; complement component C1 complex; immune response; innate immune response; response to glucocorticoid stimulus",PF00386;PF01391;,,,,,,,,,C1QB_RAT,Rattus norvegicus (Rat),"aging [GO:0007568]; brain development [GO:0007420]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; response to glucocorticoid [GO:0051384]; response to organic substance [GO:0010033]" comp109647_c0_seq1,709,42.7362,0.61922328,1258,8172,,3.00E-16,Q9BUT9,Protein FAM195A,Protein FAM195A,,,PF14799;,,,1.00E-55,ruditapes_lrc9554,,,,,F195A_HUMAN,Homo sapiens (Human), comp109660_c2_seq1,867,42.2145,0.62747071,55,26,,8.00E-61,Q5F3L9,Protein FAM65B (Myogenesis-related and NCAM-associated protein) (MYONAP),Protein FAM65B (Myogenesis-related and NCAM-associated protein) (MYONAP),,,PF15903;,9.00E-67,CHOYP_FA65A.1.1,,,,,,,FA65B_CHICK,Gallus gallus (Chicken),sensory perception of sound [GO:0007605] comp109663_c1_seq1,1002,40.519,0.51613666,60,31,,2.00E-65,Q9W6Z2,TATA box-binding protein-like protein 1 (TBP-like protein 1) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (xlTLF),TATA box-binding protein-like protein 1 (TBP-like protein 1) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (xlTLF),GO:0003677; GO:0006352; GO:0005737; GO:0009790; GO:0005634; GO:0006355; GO:0006366,"DNA binding; DNA-dependent transcription, initiation; cytoplasm; embryo development; nucleus; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF00352;,5.00E-52,CHOYP_PHUM_PHUM375280.2.2,,,,,,,TBPL1_XENLA,Xenopus laevis (African clawed frog),"DNA-templated transcription, initiation [GO:0006352]; embryo development [GO:0009790]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp109664_c0_seq1,627,44.4976,0.99640617,0,80,,3.00E-08,Q0DZP5,Probable calcium-binding protein CML17 (Calmodulin-like protein 17),Probable calcium-binding protein CML17 (Calmodulin-like protein 17),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CML17_ORYSJ,Oryza sativa subsp. japonica (Rice), comp109675_c0_seq1,1109,36.6096,0.64081377,2584,9642,,1.00E-45,P62315,Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1),Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1),GO:0008380; GO:0005689; GO:0071013; GO:0005737; GO:0006397; GO:0005634,RNA splicing; U12-type spliceosomal complex; catalytic step 2 spliceosome; cytoplasm; mRNA processing; nucleus,PF01423;,4.00E-53,CHOYP_LOC552559.1.2,,,,,,,SMD1_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; xenophagy [GO:0098792] comp109695_c1_seq1,385,40.7792,1.81505927,5,47,,3.00E-34,Q6R520,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,5.00E-34,CHOYP_ACA1_091870.1.1,,,,,,,CALM_OREMO,Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica), comp109701_c0_seq1,613,48.2871,0.47793167,8,64,,1.00E-90,Q86WU2,"Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)","Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)",GO:0004458; GO:0008762; GO:0050660; GO:0005743; GO:0005739,D-lactate dehydrogenase (cytochrome) activity; UDP-N-acetylmuramate dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrial inner membrane; mitochondrion,PF02913;PF01565;,3.00E-77,CHOYP_LOC100377100.1.1,,,,,,,LDHD_HUMAN,Homo sapiens (Human), comp109706_c0_seq1,688,42.1512,0.62454213,21,41,,1.00E-57,Q8TDB6,E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),GO:0005737; GO:0006302; GO:0042393; GO:0010390; GO:0005634; GO:0004842; GO:0008270,cytoplasm; double-strand break repair; histone binding; histone monoubiquitination; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,DTX3L_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209] comp109710_c0_seq1,887,41.8264,0.59510565,26,148,,6.00E-73,Q92535,Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C),Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C),GO:0006501; GO:0003824; GO:0005789; GO:0000506; GO:0016021; GO:0017176; GO:0016254,C-terminal protein lipidation; catalytic activity; endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to membrane; phosphatidylinositol N-acetylglucosaminyltransferase activity; preassembly of GPI anchor in ER membrane,PF06432;,,,,,,,,,PIGC_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp109715_c0_seq1,714,35.014,0.55265809,32,49,,1.00E-31,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp109717_c0_seq1,236,41.1017,0.20955283,0,14,,2.00E-25,Q12768,WASH complex subunit strumpellin,WASH complex subunit strumpellin (Strumpellin),GO:0071203; GO:0008219; GO:0016197; GO:0005768,WASH complex; cell death; endosomal transport; endosome,PF10266;,7.00E-23,CHOYP_STRUM.1.1,,,,,,,STRUM_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; oocyte maturation [GO:0001556]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; spindle assembly involved in meiosis [GO:0090306] comp109717_c1_seq1,449,43.2071,0.76530992,3,38,,2.00E-18,Q54IR8,WASH complex subunit strumpellin homolog,WASH complex subunit strumpellin homolog,GO:0071203,WASH complex,PF10266;,,,,,,,,,STRUM_DICDI,Dictyostelium discoideum (Slime mold),actin filament polymerization [GO:0030041]; exocytosis [GO:0006887]; phagosome reneutralization [GO:0044655] comp109718_c0_seq1,1593,34.9655,0.8459411,138,164,,4.00E-20,P50615,Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5),Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5),,,PF07742;,,,1.00E-14,ruditapes2_c4234,,,,,BTG3_MOUSE,Mus musculus (Mouse),negative regulation of mitotic cell cycle [GO:0045930] comp109718_c0_seq3,1641,35.4052,0.87807519,11,10,,2.00E-42,P34743,Protein BTG1 (B-cell translocation gene 1 protein),Protein BTG1 (B-cell translocation gene 1 protein),GO:0005737; GO:0019899; GO:0008285; GO:0005634; GO:0045766; GO:0045603; GO:2000271; GO:0045663,cytoplasm; enzyme binding; negative regulation of cell proliferation; nucleus; positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; positive regulation of fibroblast apoptotic process; positive regulation of myoblast differentiation,PF07742;,,,1.00E-54,ruditapes2_c3113,,,,,BTG1_CHICK,Gallus gallus (Chicken),negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663] comp109726_c0_seq1,351,41.3105,0.21187973,5,20,,6.00E-08,Q9D2N9,Vacuolar protein sorting-associated protein 33A,Vacuolar protein sorting-associated protein 33A,GO:0031902; GO:0005765; GO:0043473; GO:0030220; GO:0015031; GO:0048070; GO:0006904; GO:0016192,late endosome membrane; lysosomal membrane; pigmentation; platelet formation; protein transport; regulation of developmental pigmentation; vesicle docking involved in exocytosis; vesicle-mediated transport,PF00995;,,,,,,,,,VP33A_MOUSE,Mus musculus (Mouse),autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; lysosome localization [GO:0032418]; melanosome localization [GO:0032400]; pigmentation [GO:0043473]; platelet formation [GO:0030220]; protein transport [GO:0015031]; regulation of developmental pigmentation [GO:0048070]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] comp109726_c1_seq1,395,39.7468,0.3448298,13,37,,1.00E-34,P59016,Vacuolar protein sorting-associated protein 33B,Vacuolar protein sorting-associated protein 33B,GO:0030897; GO:0031902; GO:0005765; GO:0032418; GO:0032400; GO:0048471; GO:0031091; GO:0070889; GO:0015031; GO:0006904; GO:0016192,HOPS complex; late endosome membrane; lysosomal membrane; lysosome localization; melanosome localization; perinuclear region of cytoplasm; platelet alpha granule; platelet alpha granule organization; protein transport; vesicle docking involved in exocytosis; vesicle-mediated transport,PF00995;,,,,,,,,,VP33B_MOUSE,Mus musculus (Mouse),endosome organization [GO:0007032]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] comp109735_c0_seq1,1227,42.7873,0.52590265,3643,596,,3.00E-61,O75031,Heat shock factor 2-binding protein,Heat shock factor 2-binding protein,GO:0005829; GO:0007283; GO:0006366,cytosol; spermatogenesis; transcription from RNA polymerase II promoter,,,,,,,,,,HSF2B_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366] comp109736_c0_seq1,583,42.1955,0.84973795,12,64,,1.00E-26,Q8NE62,"Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)","Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)",GO:0008812; GO:0050660; GO:0019285; GO:0005743,choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline; mitochondrial inner membrane,PF05199;PF00732;,1.00E-25,CHOYP_LOC100877554.1.2,1.00E-16,ruditapes_c10345,,,,,CHDH_HUMAN,Homo sapiens (Human),choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285] comp109740_c0_seq1,249,59.8394,1.19487221,0,14,,3.00E-12,A0QNG3,Penicillin-binding protein A (PBPA),Penicillin-binding protein A (PBPA),GO:0016021; GO:0008658; GO:0009252; GO:0005886; GO:0008360; GO:0016740,integral to membrane; penicillin binding; peptidoglycan biosynthetic process; plasma membrane; regulation of cell shape; transferase activity,PF00905;,,,,,,,,,PBPA_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp109764_c0_seq1,333,41.1411,0.21355691,2,35,,6.00E-10,P41696,Asparagine-rich zinc finger protein AZF1,Asparagine-rich zinc finger protein AZF1,GO:0000978; GO:0001077; GO:0071322; GO:0005829; GO:0046872; GO:0005634; GO:0060237,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to carbohydrate stimulus; cytosol; metal ion binding; nucleus; regulation of fungal-type cell wall organization,PF13912;,,,,,,,,,AZF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp109771_c0_seq1,329,43.769,0.51562976,20,33,,1.00E-39,Q0P4Q4,FERM domain-containing protein 3,FERM domain-containing protein 3,GO:0005737; GO:0005856; GO:0019898; GO:0016021,cytoplasm; cytoskeleton; extrinsic to membrane; integral to membrane,PF08736;PF09380;PF00373;PF09379;,1.00E-46,CHOYP_ISCW_ISCW003928.1.1,,,,,,,FRMD3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp109789_c1_seq1,1353,31.7073,0.29432239,749,4156,,6.00E-18,Q5JTJ3,Cytochrome c oxidase assembly factor 6 homolog,Cytochrome c oxidase assembly factor 6 homolog,GO:0004129; GO:0005739,cytochrome-c oxidase activity; mitochondrion,PF02297;,,,,,,,,,CA031_HUMAN,Homo sapiens (Human),plasma membrane ATP synthesis coupled electron transport [GO:0042774]; respiratory chain complex IV assembly [GO:0008535] comp109794_c0_seq1,309,35.2751,0.62753694,5,31,,2.00E-08,Q5BKK6,Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-),Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-),GO:0016491; GO:0005578,oxidoreductase activity; proteinaceous extracellular matrix,PF01408;,,,,,,,,,GFOD2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),extracellular matrix organization [GO:0030198]; oxidation-reduction process [GO:0055114] comp109796_c0_seq1,397,47.8589,0.45742159,12,15,,6.00E-09,Q4KMG0,Cell adhesion molecule-related/down-regulated by oncogenes,Cell adhesion molecule-related/down-regulated by oncogenes,GO:0009952; GO:0007155; GO:0001708; GO:0021987; GO:0010172; GO:0060059; GO:0016021; GO:0002088; GO:0042692; GO:0007520; GO:0005886; GO:0043410; GO:0051149; GO:2000179; GO:0045666; GO:0001934; GO:0048643; GO:0051057; GO:0045944; GO:0043497; GO:0014816; GO:0007224,anterior/posterior pattern specification; cell adhesion; cell fate specification; cerebral cortex development; embryonic body morphogenesis; embryonic retina morphogenesis in camera-type eye; integral to membrane; lens development in camera-type eye; muscle cell differentiation; myoblast fusion; plasma membrane; positive regulation of MAPK cascade; positive regulation of muscle cell differentiation; positive regulation of neural precursor cell proliferation; positive regulation of neuron differentiation; positive regulation of protein phosphorylation; positive regulation of skeletal muscle tissue development; positive regulation of small GTPase mediated signal transduction; positive regulation of transcription from RNA polymerase II promoter; regulation of protein heterodimerization activity; satellite cell differentiation; smoothened signaling pathway,PF00041;PF07679;,,,,,,,,,CDON_HUMAN,Homo sapiens (Human),anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein heterodimerization activity [GO:0043497]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224] comp109797_c0_seq1,2389,39.5144,0.29134766,102,620,,2.00E-09,Q9LEB4,Polyadenylate-binding protein RBP45 (Poly(A)-binding protein RBP45) (RNA-binding protein 45) (NplRBP45),Polyadenylate-binding protein RBP45 (Poly(A)-binding protein RBP45) (RNA-binding protein 45) (NplRBP45),GO:0006397; GO:0000166; GO:0005634; GO:0008143,mRNA processing; nucleotide binding; nucleus; poly(A) RNA binding,PF00076;,0,CHOYP_RBM22.1.1,,,,,,,RBP45_NICPL,Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco),mRNA processing [GO:0006397] comp109797_c0_seq2,2402,39.4671,0.29035901,29,203,,0,Q6P616,Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22),Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22),GO:0005737; GO:0045292; GO:0046872; GO:0007275; GO:0000166; GO:0005634; GO:0033120; GO:0036002; GO:0017069; GO:0005681,"cytoplasm; mRNA cis splicing, via spliceosome; metal ion binding; multicellular organismal development; nucleotide binding; nucleus; positive regulation of RNA splicing; pre-mRNA binding; snRNA binding; spliceosomal complex",PF00076;,0,CHOYP_RBM22.1.1,2.00E-33,ruditapes_c8761,,,,,RBM22_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"chordate embryonic development [GO:0043009]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387]" comp109798_c0_seq1,298,43.9597,0.55836296,25,26,,7.00E-08,Q5E9Z7,DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D),DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D),GO:0003677; GO:0005666; GO:0003899; GO:0051607; GO:0045087; GO:0045089; GO:0032728; GO:0006383,DNA binding; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; defense response to virus; innate immune response; positive regulation of innate immune response; positive regulation of interferon-beta production; transcription from RNA polymerase III promoter,PF05132;,,,,,,,,,RPC4_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription from RNA polymerase III promoter [GO:0006383] comp109819_c0_seq2,487,43.3265,0.35659632,20,0,,6.00E-39,Q9FHN8,Kinesin-like calmodulin-binding protein (Protein ZWICHEL),Kinesin-like calmodulin-binding protein (Protein ZWICHEL),GO:0043531; GO:0005524; GO:0016887; GO:0005509; GO:0005516; GO:0005871; GO:0008017; GO:0003777; GO:0007018; GO:0016491; GO:0010091,ADP binding; ATP binding; ATPase activity; calcium ion binding; calmodulin binding; kinesin complex; microtubule binding; microtubule motor activity; microtubule-based movement; oxidoreductase activity; trichome branching,PF00373;PF09379;PF00225;PF00784;,2.00E-79,CHOYP_LOC373208.1.1,,,,,,,KCBP_ARATH,Arabidopsis thaliana (Mouse-ear cress),microtubule-based movement [GO:0007018]; trichome branching [GO:0010091] comp109824_c0_seq1,418,42.3445,0.22075996,23,4,,,,,,,,,5.00E-22,CHOYP_NEMVEDRAFT_V1G246103.1.2,,,,,,,,, comp109829_c0_seq1,751,42.743,0.70489111,3,2,,2.00E-87,Q7T292,Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28),Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28),GO:0016021; GO:0006811; GO:0055072; GO:0005743,integral to membrane; ion transport; iron ion homeostasis; mitochondrial inner membrane,PF00153;,,,,,,,,,MFRN2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; translation [GO:0006412] comp109829_c0_seq2,676,45.5621,0.69167066,0,5,,7.00E-88,Q7T292,Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28),Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28),GO:0016021; GO:0006811; GO:0055072; GO:0005743,integral to membrane; ion transport; iron ion homeostasis; mitochondrial inner membrane,PF00153;,3.00E-34,CHOYP_SLC25A37.1.1,,,,,,,MFRN2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; translation [GO:0006412] comp109831_c0_seq1,396,46.2121,0.33725943,16,49,,1.00E-57,Q7SX99,"Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)","Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)",GO:0004333; GO:0006106; GO:0005739; GO:0006099; GO:0045239,fumarate hydratase activity; fumarate metabolic process; mitochondrion; tricarboxylic acid cycle; tricarboxylic acid cycle enzyme complex,PF10415;PF00206;,6.00E-46,CHOYP_FUMH.2.2,,,,,,,FUMH_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099] comp109845_c0_seq1,1051,48.0495,0.46563977,37,63,,3.00E-49,Q8K1R7,Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9),Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9),GO:0005524; GO:0051301; GO:0046872; GO:0005739; GO:0007067; GO:0005634; GO:0019901; GO:0004674,ATP binding; cell division; metal ion binding; mitochondrion; mitosis; nucleus; protein kinase binding; protein serine/threonine kinase activity,PF00069;PF00415;,1.00E-90,CHOYP_BRAFLDRAFT_124709.1.1,,,,,,,NEK9_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468] comp109847_c0_seq1,475,45.6842,0.58119916,11,25,,8.00E-29,Q8SPX7,Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),GO:0003857; GO:0050104; GO:0070403; GO:0005829; GO:0006631,3-hydroxyacyl-CoA dehydrogenase activity; L-gulonate 3-dehydrogenase activity; NAD+ binding; cytosol; fatty acid metabolic process,PF00725;PF02737;,,,,,,,,,CRYL1_BOVIN,Bos taurus (Bovine),fatty acid metabolic process [GO:0006631] comp109847_c1_seq1,410,44.6341,0.69192331,9,36,,8.00E-28,Q5RDZ2,Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),GO:0003857; GO:0050104; GO:0070403; GO:0005829; GO:0006631,3-hydroxyacyl-CoA dehydrogenase activity; L-gulonate 3-dehydrogenase activity; NAD+ binding; cytosol; fatty acid metabolic process,PF00725;PF02737;,1.00E-36,CHOYP_LOC100374307.1.1,,,,,,,CRYL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),fatty acid metabolic process [GO:0006631] comp109855_c0_seq1,855,46.3158,0.46721311,51,15,,3.00E-48,Q2T9T9,F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9),F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9),,,PF00400;,,,,,,,,,FBXW9_BOVIN,Bos taurus (Bovine), comp109861_c0_seq1,622,37.1383,0.51799076,258,1901,,5.00E-19,Q9PRL8,Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI),Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI),GO:0005794; GO:0005783; GO:0000062; GO:0008289; GO:0006810,Golgi apparatus; endoplasmic reticulum; fatty-acyl-CoA binding; lipid binding; transport,PF00887;,5.00E-24,CHOYP_ACBP.1.4,,,,,,,ACBP_CHICK,Gallus gallus (Chicken),transport [GO:0006810] comp109881_c0_seq2,332,37.0482,1.26274168,0,9,,3.00E-08,Q08B72,"Myb-related transcription factor, partner of profilin (Myb-related protein p42POP)","Myb-related transcription factor, partner of profilin (Myb-related protein p42POP)",GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13873;,,,,,,,,,MYPOP_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109887_c0_seq2,266,44.3609,0.46074853,12,0,,2.00E-20,P13056,Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2),Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2),GO:0003677; GO:0016605; GO:0000122; GO:0005654; GO:0048386; GO:0043565; GO:0003700; GO:0003707; GO:0006367; GO:0008270,DNA binding; PML body; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of retinoic acid receptor signaling pathway; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription initiation from RNA polymerase II promoter; zinc ion binding,PF00104;PF00105;,2.00E-19,CHOYP_LOC100372393.1.1,,,,,,,NR2C1_HUMAN,Homo sapiens (Human),positive regulation of retinoic acid receptor signaling pathway [GO:0048386]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp109889_c0_seq1,271,44.2804,0.70366006,9,7,,6.00E-18,P50053,Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),GO:0005524; GO:0005829; GO:0006001; GO:0004454; GO:0044281,ATP binding; cytosol; fructose catabolic process; ketohexokinase activity; small molecule metabolic process,PF00294;,,,,,,,,,KHK_HUMAN,Homo sapiens (Human),fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043] comp109900_c0_seq1,466,46.3519,0.56072299,30,10,,5.00E-86,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,6.00E-110,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp109910_c0_seq1,622,39.8714,1.06342187,10,84,,3.00E-22,Q9VUL9,"Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)","Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)",GO:0033932; GO:0032580; GO:0005797; GO:0036071; GO:0018392; GO:0016021; GO:0007399; GO:0006486,"1,3-alpha-L-fucosidase activity; Golgi cisterna membrane; Golgi medial cisterna; N-glycan fucosylation; glycoprotein 3-alpha-L-fucosyltransferase activity; integral to membrane; nervous system development; protein glycosylation",PF17039;PF00852;,,,,,,,,,FUCTA_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] comp109923_c0_seq1,352,51.9886,1.28178231,0,24,,9.00E-17,Q5XJ34,BTB/POZ domain-containing protein kctd15-like,BTB/POZ domain-containing protein kctd15-like,GO:0044335; GO:0090090; GO:0060037; GO:0051260,canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; negative regulation of canonical Wnt receptor signaling pathway; pharyngeal system development; protein homooligomerization,PF02214;,2.00E-26,CHOYP_LOC654911.1.1,,,,,,,KC15L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; pharyngeal system development [GO:0060037]; protein homooligomerization [GO:0051260]; regulation of RNA biosynthetic process [GO:2001141] comp109924_c0_seq1,385,43.1169,0.45952691,11,4,,2.00E-06,O88845,"A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)","A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)",GO:0005739; GO:0005886; GO:0051018; GO:0008104; GO:0038032,mitochondrion; plasma membrane; protein kinase A binding; protein localization; termination of G-protein coupled receptor signaling pathway,PF00615;,,,,,,,,,AKA10_MOUSE,Mus musculus (Mouse),protein localization [GO:0008104] comp109929_c0_seq1,301,48.1728,0.64082497,3,56,,2.00E-24,Q7M758,N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21),N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21),GO:0016324; GO:0004180; GO:0016805; GO:0016021; GO:0046872; GO:0008237; GO:0006508,apical plasma membrane; carboxypeptidase activity; dipeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; proteolysis,PF02225;PF04389;PF04253;,5.00E-20,CHOYP_LOC579656.4.5,,,,,,,NALDL_MOUSE,Mus musculus (Mouse), comp109931_c1_seq1,641,45.0858,0.31104727,12,13,,5.00E-92,O15550,Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein),Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein),GO:0000978; GO:0060070; GO:0051213; GO:0007507; GO:0051568; GO:0071558; GO:0035097; GO:0001701; GO:0048333; GO:0046872; GO:0001843; GO:0048570; GO:0003016; GO:0032525,RNA polymerase II core promoter proximal region sequence-specific DNA binding; canonical Wnt receptor signaling pathway; dioxygenase activity; heart development; histone H3-K4 methylation; histone demethylase activity (H3-K27 specific); histone methyltransferase complex; in utero embryonic development; mesodermal cell differentiation; metal ion binding; neural tube closure; notochord morphogenesis; respiratory system process; somite rostral/caudal axis specification,PF02373;PF13181;,1.00E-83,CHOYP_LOC100883412.1.1,2.00E-21,ruditapes_c8065,,,,,KDM6A_HUMAN,Homo sapiens (Human),canonical Wnt signaling pathway [GO:0060070]; heart morphogenesis [GO:0003007]; histone H3-K4 methylation [GO:0051568]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] comp109938_c0_seq1,1164,44.244,0.47837429,40,135,,3.00E-20,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp109952_c0_seq1,1708,41.6276,0.38675172,1204,5479,,7.00E-128,Q803G5,Sorting and assembly machinery component 50 homolog A,Sorting and assembly machinery component 50 homolog A,GO:0016021; GO:0005741,integral to membrane; mitochondrial outer membrane,PF01103;,,,,,,,,,SAM5A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cristae formation [GO:0042407]; liver development [GO:0001889] comp109960_c0_seq1,333,44.1441,0.96495477,8,39,,3.00E-09,Q804X6,Coagulation factor IX (EC 3.4.21.22) (Christmas factor) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain],Coagulation factor IX (EC 3.4.21.22) (Christmas factor) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain],GO:0007596; GO:0005509; GO:0005576; GO:0006508; GO:0004252,blood coagulation; calcium ion binding; extracellular region; proteolysis; serine-type endopeptidase activity,PF00008;PF00594;PF00089;,,,,,,,,,FA9_CHICK,Gallus gallus (Chicken),blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] comp109970_c0_seq1,234,47.8632,0.37516649,9,0,,2.00E-20,Q9Y6A1,Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1),Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1),GO:0001669; GO:0004169; GO:0005789; GO:0030198; GO:0016021; GO:0000030; GO:0046872; GO:0007275; GO:0006493; GO:0016529,acrosomal vesicle; dolichyl-phosphate-mannose-protein mannosyltransferase activity; endoplasmic reticulum membrane; extracellular matrix organization; integral to membrane; mannosyltransferase activity; metal ion binding; multicellular organismal development; protein O-linked glycosylation; sarcoplasmic reticulum,PF02815;PF02366;PF16192;,,,,,,,,,POMT1_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101] comp109972_c0_seq1,320,43.75,0.26252557,9,0,,1.00E-07,Q8HY11,C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299),C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299),GO:0006897; GO:0045087; GO:0016021; GO:0005537; GO:0046872,endocytosis; innate immune response; integral to membrane; mannose binding; metal ion binding,PF00059;,,,,,,,,,CLC4M_HYLSY,Symphalangus syndactylus (Siamang) (Hylobates syndactylus),adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; innate immune response [GO:0045087] comp109979_c0_seq1,269,58.7361,1.22094711,2,1,,2.00E-23,A0LV85,Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18),Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18),GO:0006284; GO:0003684; GO:0006289; GO:0008534; GO:0008270,base-excision repair; damaged DNA binding; nucleotide-excision repair; oxidized purine nucleobase lesion DNA N-glycosylase activity; zinc ion binding,PF01149;PF06831;PF06827;,,,,,,,,,FPG_ACIC1,Acidothermus cellulolyticus (strain ATCC 43068 / 11B),base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289] comp109979_c1_seq1,270,55.1852,1.22338262,2,14,,3.00E-27,A4QFD9,Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18),Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18),GO:0006284; GO:0003684; GO:0006289; GO:0008534; GO:0008270,base-excision repair; damaged DNA binding; nucleotide-excision repair; oxidized purine nucleobase lesion DNA N-glycosylase activity; zinc ion binding,PF01149;PF06831;PF06827;,,,,,,,,,FPG_CORGB,Corynebacterium glutamicum (strain R),base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289] comp109993_c0_seq1,856,38.2009,0.38514022,39,80,,9.00E-25,Q60648,Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),GO:0004563; GO:0008047; GO:0006689; GO:0007611; GO:0019915; GO:0005764; GO:0005739; GO:0050885; GO:0005730; GO:0009313,beta-N-acetylhexosaminidase activity; enzyme activator activity; ganglioside catabolic process; learning or memory; lipid storage; lysosome; mitochondrion; neuromuscular process controlling balance; nucleolus; oligosaccharide catabolic process,PF02221;,,,,,,,,,SAP3_MOUSE,Mus musculus (Mouse),ganglioside catabolic process [GO:0006689]; learning or memory [GO:0007611]; lipid storage [GO:0019915]; neurological system process [GO:0050877]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; positive regulation of hydrolase activity [GO:0051345] comp109999_c0_seq1,358,40.5028,0.57257225,28,16,,9.00E-11,Q2M2Z5,Centrosomal protein kizuna (Polo-like kinase 1 substrate 1),Centrosomal protein kizuna (Polo-like kinase 1 substrate 1),GO:0005813; GO:0005737; GO:0007051,centrosome; cytoplasm; spindle organization,,,,,,,,,,KIZ_HUMAN,Homo sapiens (Human),spindle organization [GO:0007051] comp110002_c0_seq1,761,42.9698,0.45611751,18,73,,6.00E-93,Q8JHF2,"Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)","Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)",GO:0007219; GO:0033829; GO:0055016; GO:0030173; GO:0046872; GO:0045665; GO:0007389,Notch signaling pathway; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; hypochord development; integral to Golgi membrane; metal ion binding; negative regulation of neuron differentiation; pattern specification process,PF02434;,8.00E-29,CHOYP_RFNG.1.1,,,,,,,LFNG_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fin regeneration [GO:0031101]; hypochord development [GO:0055016]; negative regulation of neuron differentiation [GO:0045665]; Notch signaling pathway [GO:0007219]; pattern specification process [GO:0007389] comp110015_c0_seq1,665,56.2406,1.22314326,0,72,,1.00E-39,P41797,Heat shock protein SSA1,Heat shock protein SSA1,GO:0005524; GO:0009986; GO:0034605; GO:0005829; GO:0030260; GO:0005576; GO:0044182; GO:0030446; GO:0044416; GO:0042277; GO:0005886; GO:0009636; GO:0006412; GO:0051082; GO:0030445,ATP binding; cell surface; cellular response to heat; cytosol; entry into host cell; extracellular region; filamentous growth of a population of unicellular organisms; hyphal cell wall; induction by symbiont of host defense response; peptide binding; plasma membrane; response to toxic substance; translation; unfolded protein binding; yeast-form cell wall,PF00012;,,,,,,,,,HSP71_CANAL,Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast),cellular response to heat [GO:0034605]; entry into host cell [GO:0030260]; induction by symbiont of host defense response [GO:0044416]; interaction with host [GO:0051701]; response to toxic substance [GO:0009636] comp110023_c0_seq1,446,43.9462,0.56564663,14,20,,1.00E-23,Q6AYC8,SH2 domain-containing protein 4A,SH2 domain-containing protein 4A,GO:0005737; GO:0010923; GO:0005634; GO:0019902,cytoplasm; negative regulation of phosphatase activity; nucleus; phosphatase binding,PF00017;,6.00E-15,CHOYP_SH24B.1.1,,,,,,,SH24A_RAT,Rattus norvegicus (Rat),negative regulation of phosphatase activity [GO:0010923] comp110031_c0_seq1,533,38.8368,0.55404836,7,10,,3.00E-56,Q61194,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Cpk-m) (Phosphoinositide 3-kinase-C2-alpha) (p170),Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Cpk-m) (Phosphoinositide 3-kinase-C2-alpha) (p170),GO:0016303; GO:0035005; GO:0005524; GO:0005794; GO:0030136; GO:0006897; GO:0006887; GO:0005634; GO:0005942; GO:0035091; GO:0048015; GO:0005886; GO:0031982,1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; Golgi apparatus; clathrin-coated vesicle; endocytosis; exocytosis; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol binding; phosphatidylinositol-mediated signaling; plasma membrane; vesicle,PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;,9.00E-39,CHOYP_LOC100121969.1.1,,,,,,,P3C2A_MOUSE,Mus musculus (Mouse),autophagosome organization [GO:1905037]; cellular response to starvation [GO:0009267]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; negative regulation of zinc ion transmembrane transport [GO:0071583]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015] comp110034_c0_seq1,330,46.9697,0.61545528,10,14,,1.00E-35,Q91ZN7,Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1),Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1),GO:0005524; GO:0000077; GO:0006975; GO:0006281; GO:0071313; GO:0071260; GO:0005813; GO:0000785; GO:0048096; GO:0000781; GO:0000794; GO:0005737; GO:0035402; GO:0045839; GO:0010569; GO:2000615; GO:0046602; GO:0010767,"ATP binding; DNA damage checkpoint; DNA damage induced protein phosphorylation; DNA repair; cellular response to caffeine; cellular response to mechanical stimulus; centrosome; chromatin; chromatin-mediated maintenance of transcription; chromosome, telomeric region; condensed nuclear chromosome; cytoplasm; histone kinase activity (H3-T11 specific); negative regulation of mitosis; regulation of double-strand break repair via homologous recombination; regulation of histone H3-K9 acetylation; regulation of mitotic centrosome separation; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage",PF00069;,6.00E-26,CHOYP_LOC100367549.1.1,,,,,,,CHK1_RAT,Rattus norvegicus (Rat),cellular response to caffeine [GO:0071313]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to organic substance [GO:0071310]; chromatin-mediated maintenance of transcription [GO:0048096]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767] comp110040_c0_seq1,872,35.5505,0.52121694,19,117,,7.00E-30,Q1JQE6,Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1),Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1),GO:0004091; GO:0005783; GO:0016021; GO:0016042; GO:0042301; GO:0006470; GO:0017171; GO:0006805,carboxylesterase activity; endoplasmic reticulum; integral to membrane; lipid catabolic process; phosphate ion binding; protein dephosphorylation; serine hydrolase activity; xenobiotic metabolic process,PF07859;,,,5.00E-11,ruditapes_c9860,,,,,NCEH1_BOVIN,Bos taurus (Bovine),catabolic process [GO:0009056]; lipid catabolic process [GO:0016042]; protein dephosphorylation [GO:0006470]; SMAD protein signal transduction [GO:0060395]; xenobiotic metabolic process [GO:0006805] comp110041_c0_seq1,377,44.8276,0.53090261,3,0,,2.00E-08,Q12873,Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH),Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH),GO:0005524; GO:0004003; GO:0003677; GO:0016581; GO:0005813; GO:0051297; GO:0006333; GO:0016568; GO:0005737; GO:0045111; GO:0005730; GO:0006357; GO:0007051; GO:0006351; GO:0008270,"ATP binding; ATP-dependent DNA helicase activity; DNA binding; NuRD complex; centrosome; centrosome organization; chromatin assembly or disassembly; chromatin modification; cytoplasm; intermediate filament cytoskeleton; nucleolus; regulation of transcription from RNA polymerase II promoter; spindle organization; transcription, DNA-dependent; zinc ion binding",PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;,,,,,,,,,CHD3_HUMAN,Homo sapiens (Human),"centrosome organization [GO:0051297]; chromatin assembly or disassembly [GO:0006333]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle organization [GO:0007051]; transcription, DNA-templated [GO:0006351]" comp110041_c0_seq2,650,45.5385,0.60144267,9,78,,3.00E-11,O97159,Chromodomain-helicase-DNA-binding protein Mi-2 homolog (EC 3.6.4.12) (ATP-dependent helicase Mi-2) (dMi-2),Chromodomain-helicase-DNA-binding protein Mi-2 homolog (EC 3.6.4.12) (ATP-dependent helicase Mi-2) (dMi-2),GO:0005524; GO:0004003; GO:0003677; GO:0016581; GO:0048813; GO:0007517; GO:0000122; GO:0031491; GO:0042766; GO:0005700; GO:0006351; GO:0008270,"ATP binding; ATP-dependent DNA helicase activity; DNA binding; NuRD complex; dendrite morphogenesis; muscle organ development; negative regulation of transcription from RNA polymerase II promoter; nucleosome binding; nucleosome mobilization; polytene chromosome; transcription, DNA-dependent; zinc ion binding",PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;,,,,,,,,,CHDM_DROME,Drosophila melanogaster (Fruit fly),"ATP-dependent chromatin remodeling [GO:0043044]; chromosome decondensation [GO:0051312]; chromosome organization [GO:0051276]; dendrite morphogenesis [GO:0048813]; muscle organ development [GO:0007517]; negative regulation of cohesin loading [GO:0071923]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome mobilization [GO:0042766]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp110041_c1_seq1,469,45.629,0.49279385,21,0,,2.00E-77,A4IHD2,Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2),Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2),GO:0005524; GO:0003677; GO:0004386; GO:0005634,ATP binding; DNA binding; helicase activity; nucleus,PF00271;PF00176;,2.00E-65,CHOYP_ARIP4.3.3,,,,,,,ARIP4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp110043_c2_seq2,327,45.8716,0.46857581,9,0,,4.00E-06,Q6GMD2,WD repeat-containing protein 61,WD repeat-containing protein 61,GO:0016593; GO:0055087; GO:0080182; GO:0045638; GO:0051571; GO:2001162; GO:0032968; GO:0045944; GO:0035327,Cdc73/Paf1 complex; Ski complex; histone H3-K4 trimethylation; negative regulation of myeloid cell differentiation; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K79 methylation; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcriptionally active chromatin,PF00400;,,,,,,,,,WDR61_XENLA,Xenopus laevis (African clawed frog),histone H3-K4 trimethylation [GO:0080182]; negative regulation of myeloid cell differentiation [GO:0045638]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp110047_c0_seq2,1618,40.2967,0.50340162,33,56,,0,Q9BSU1,UPF0183 protein C16orf70,UPF0183 protein C16orf70,,,PF03676;,0,CHOYP_BRAFLDRAFT_236516.1.1,,,1.00E-90,FP003003.p.cg.6,7,,CP070_HUMAN,Homo sapiens (Human), comp110063_c0_seq2,646,39.7833,0.982091,11,53,,,,,,,,,,,2.00E-26,ruditapes_c10937,,,,,,, comp110079_c1_seq1,252,65.0794,0.98548368,0,20,,5.00E-07,P40416,"Iron-sulfur clusters transporter ATM1, mitochondrial","Iron-sulfur clusters transporter ATM1, mitochondrial",GO:0005524; GO:0042626; GO:0006879; GO:0016021; GO:0006811; GO:0005743,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cellular iron ion homeostasis; integral to membrane; ion transport; mitochondrial inner membrane",PF00664;PF00005;,,,,,,,,,ATM1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular iron ion homeostasis [GO:0006879]; ion transport [GO:0006811]; small molecule metabolic process [GO:0044281] comp110084_c0_seq1,662,38.3686,0.73991117,588,2418,,2.00E-79,Q9Y248,DNA replication complex GINS protein PSF2 (GINS complex subunit 2),DNA replication complex GINS protein PSF2 (GINS complex subunit 2),GO:0006271; GO:0000278; GO:0005654,DNA strand elongation involved in DNA replication; mitotic cell cycle; nucleoplasm,PF05916;,5.00E-94,CHOYP_BRAFLDRAFT_118797.2.2,4.00E-112,ruditapes_c14476,2.00E-91,AM866236.p.cg.6,8,,PSF2_HUMAN,Homo sapiens (Human),DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975] comp110088_c0_seq1,593,42.4958,0.89937799,3,88,,4.00E-66,Q6NYV8,Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51),Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51),GO:0003841; GO:0016024; GO:0005789; GO:0001885; GO:0060217; GO:0016021,1-acylglycerol-3-phosphate O-acyltransferase activity; CDP-diacylglycerol biosynthetic process; endoplasmic reticulum membrane; endothelial cell development; hemangioblast cell differentiation; integral to membrane,PF16076;PF01553;,,,,,,,,,LCLT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),CDP-diacylglycerol biosynthetic process [GO:0016024]; embryonic hemopoiesis [GO:0035162]; endothelial cell development [GO:0001885]; hemangioblast cell differentiation [GO:0060217] comp110093_c0_seq1,405,45.9259,0.70617314,7,39,,8.00E-07,Q96QU1,Protocadherin-15,Protocadherin-15,GO:0005509; GO:0050957; GO:0005576; GO:0005615; GO:0007156; GO:0016021; GO:0045494; GO:0001750; GO:0005886; GO:0050953; GO:0007605; GO:0032420; GO:0045202,calcium ion binding; equilibrioception; extracellular region; extracellular space; homophilic cell adhesion; integral to membrane; photoreceptor cell maintenance; photoreceptor outer segment; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilium; synapse,PF00028;,,,,,,,,,PCD15_HUMAN,Homo sapiens (Human),equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear development [GO:0048839]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] comp110096_c0_seq1,624,42.1474,0.3425292,0,2,,1.00E-71,A1L1R5,Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),GO:0030030; GO:0035335; GO:0004725; GO:0008138,cell projection organization; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,8.00E-28,CHOYP_LOC100890521.1.1,,,,,,,PTPC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium morphogenesis [GO:0060271] comp110096_c0_seq3,476,42.8571,0.23502272,0,0,,6.00E-41,A1L1R5,Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),GO:0030030; GO:0035335; GO:0004725; GO:0008138,cell projection organization; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,,,,,,,,,PTPC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium morphogenesis [GO:0060271] comp110117_c0_seq1,409,44.4988,0.30780965,15,11,,3.00E-43,P17706,Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP),Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP),GO:0030183; GO:0030217; GO:0005783; GO:0005793; GO:0030218; GO:0042593; GO:0008286; GO:0060333; GO:0070373; GO:0050860; GO:0008285; GO:0050922; GO:0042059; GO:0050728; GO:0046627; GO:0060336; GO:1902206; GO:1902215; GO:0070104; GO:0010888; GO:1902227; GO:0045650; GO:2000587; GO:1902233; GO:1902212; GO:0010804; GO:0060339; GO:0042512; GO:0042518; GO:0042524; GO:0042527; GO:0004726; GO:0005654; GO:0005634; GO:0005886; GO:0045722; GO:0004725; GO:1902202,B cell differentiation; T cell differentiation; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; erythrocyte differentiation; glucose homeostasis; insulin receptor signaling pathway; interferon-gamma-mediated signaling pathway; negative regulation of ERK1 and ERK2 cascade; negative regulation of T cell receptor signaling pathway; negative regulation of cell proliferation; negative regulation of chemotaxis; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of inflammatory response; negative regulation of insulin receptor signaling pathway; negative regulation of interferon-gamma-mediated signaling pathway; negative regulation of interleukin-2-mediated signaling pathway; negative regulation of interleukin-4-mediated signaling pathway; negative regulation of interleukin-6-mediated signaling pathway; negative regulation of lipid storage; negative regulation of macrophage colony-stimulating factor signaling pathway; negative regulation of macrophage differentiation; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of positive thymic T cell selection; negative regulation of prolactin signaling pathway; negative regulation of tumor necrosis factor-mediated signaling pathway; negative regulation of type I interferon-mediated signaling pathway; negative regulation of tyrosine phosphorylation of Stat1 protein; negative regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of tyrosine phosphorylation of Stat6 protein; non-membrane spanning protein tyrosine phosphatase activity; nucleoplasm; nucleus; plasma membrane; positive regulation of gluconeogenesis; protein tyrosine phosphatase activity; regulation of hepatocyte growth factor receptor signaling pathway,PF00102;,6.00E-21,CHOYP_BRAFLDRAFT_68592.1.1,,,,,,,PTN2_HUMAN,Homo sapiens (Human),B cell differentiation [GO:0030183]; erythrocyte differentiation [GO:0030218]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of interleukin-2-mediated signaling pathway [GO:1902206]; negative regulation of interleukin-4-mediated signaling pathway [GO:1902215]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of positive thymic T cell selection [GO:1902233]; negative regulation of prolactin signaling pathway [GO:1902212]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of tyrosine phosphorylation of Stat1 protein [GO:0042512]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; negative regulation of tyrosine phosphorylation of Stat6 protein [GO:0042527]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; T cell differentiation [GO:0030217] comp110125_c0_seq1,393,47.3282,0.92651981,1,16,,1.00E-49,P97363,Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2),Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2),GO:0046513; GO:0016021; GO:0005739; GO:0030170; GO:0004758; GO:0017059; GO:0046511; GO:0006686; GO:0046512,ceramide biosynthetic process; integral to membrane; mitochondrion; pyridoxal phosphate binding; serine C-palmitoyltransferase activity; serine C-palmitoyltransferase complex; sphinganine biosynthetic process; sphingomyelin biosynthetic process; sphingosine biosynthetic process,PF00155;,4.00E-42,CHOYP_SPTC2.1.4,,,,,,,SPTC2_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] comp110125_c2_seq1,425,41.1765,0.83529874,2,85,,2.00E-44,Q9NUV7,Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3),Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3),GO:0016021; GO:0030170; GO:0004758; GO:0017059; GO:0044281; GO:0046520,integral to membrane; pyridoxal phosphate binding; serine C-palmitoyltransferase activity; serine C-palmitoyltransferase complex; small molecule metabolic process; sphingoid biosynthetic process,PF00155;,,,,,,,,,SPTC3_HUMAN,Homo sapiens (Human),sphingoid biosynthetic process [GO:0046520]; sphingolipid biosynthetic process [GO:0030148] comp110133_c0_seq1,981,39.5515,0.60069211,4742,2,male>female,3.00E-32,Q4KKZ1,Uncharacterized protein C1orf158 homolog,Uncharacterized protein C1orf158 homolog,,,,9.00E-55,CHOYP_LOC100368360.1.1,,,,,,,CA158_MOUSE,Mus musculus (Mouse), comp110142_c0_seq1,1231,41.511,0.52848029,26,37,,3.00E-07,P35789,Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34),Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34),GO:0003677; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZNF93_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transposon integration [GO:0070895]; transcription, DNA-templated [GO:0006351]" comp110142_c0_seq2,830,38.4337,0.72306702,0,0,,5.00E-09,Q15935,Zinc finger protein 77 (ZNFpT1),Zinc finger protein 77 (ZNFpT1),GO:0003677; GO:0005737; GO:0046872; GO:0005730; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF77_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp110143_c0_seq1,921,32.139,0.65149879,442,3135,,1.00E-09,P82930,"28S ribosomal protein S34, mitochondrial (MRP-S34) (S34mt)","28S ribosomal protein S34, mitochondrial (MRP-S34) (S34mt)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF16053;,,,2.00E-17,ruditapes2_c127,,,,,RT34_HUMAN,Homo sapiens (Human),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126] comp110156_c0_seq1,312,47.7564,0.62852051,8,45,,4.00E-09,O42384,5-hydroxytryptamine receptor 1A-beta (5-HT-1A-beta) (5-HT1A-beta) (F1B) (Serotonin receptor 1A-beta),5-hydroxytryptamine receptor 1A-beta (5-HT-1A-beta) (5-HT1A-beta) (F1B) (Serotonin receptor 1A-beta),GO:0007198; GO:0007610; GO:0008283; GO:0005887; GO:0050795; GO:0046883; GO:0004993; GO:0042310,adenylate cyclase-inhibiting serotonin receptor signaling pathway; behavior; cell proliferation; integral to plasma membrane; regulation of behavior; regulation of hormone secretion; serotonin receptor activity; vasoconstriction,PF00001;,2.00E-12,CHOYP_ISCW_ISCW009595.1.2,,,,,,,5H1AB_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; cell proliferation [GO:0008283]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; serotonin receptor signaling pathway [GO:0007210]; vasoconstriction [GO:0042310] comp110159_c0_seq1,629,40.2226,0.70866321,0,0,,8.00E-62,Q9TYU5,Histone acetyltransferase Tip60 homolog (EC 2.3.1.48) (Myst family histone acetyltransferase-like protein 1),Histone acetyltransferase Tip60 homolog (EC 2.3.1.48) (Myst family histone acetyltransferase-like protein 1),GO:0001708; GO:0016573; GO:0004402; GO:0007275; GO:0005634; GO:0071168; GO:0006355; GO:0006351,"cell fate specification; histone acetylation; histone acetyltransferase activity; multicellular organismal development; nucleus; protein localization to chromatin; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01853;PF11717;,2.00E-60,CHOYP_KAT5.1.1,,,,,,,TIP60_CAEEL,Caenorhabditis elegans,"cell fate specification [GO:0001708]; multicellular organism development [GO:0007275]; protein localization to chromatin [GO:0071168]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp110159_c0_seq2,906,41.8322,0.63242672,7,63,,4.00E-102,Q5RBG4,Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5),Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5),GO:0006978; GO:0032777; GO:0016573; GO:0004402; GO:0046872; GO:0005730; GO:0048471; GO:0045893; GO:0040008; GO:0003713; GO:0006351,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; Piccolo NuA4 histone acetyltransferase complex; histone acetylation; histone acetyltransferase activity; metal ion binding; nucleolus; perinuclear region of cytoplasm; positive regulation of transcription, DNA-dependent; regulation of growth; transcription coactivator activity; transcription, DNA-dependent",PF01853;PF11717;,,,,,,,,,KAT5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp110161_c2_seq1,487,42.2998,0.51182519,15,36,,1.00E-36,O13134,Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4),Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4),GO:0016323; GO:0005452; GO:0016021; GO:0006814; GO:0015293,basolateral plasma membrane; inorganic anion exchanger activity; integral to membrane; sodium ion transport; symporter activity,PF07565;PF00955;,2.00E-34,CHOYP_B3A2.2.2,,,,,,,S4A4_AMBTI,Ambystoma tigrinum (Eastern tiger salamander),sodium ion transport [GO:0006814] comp110172_c0_seq1,468,42.735,0.70350321,13,0,,3.00E-09,Q54ZN3,Probable protein kinase DDB_G0277539 (EC 2.7.11.1),Probable protein kinase DDB_G0277539 (EC 2.7.11.1),GO:0005524; GO:0046872; GO:0005634; GO:0004674; GO:0004713; GO:0051726,ATP binding; metal ion binding; nucleus; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of cell cycle,PF00069;,,,,,,,,,Y0004_DICDI,Dictyostelium discoideum (Slime mold), comp110172_c2_seq1,344,42.4419,0.84162843,14,15,,1.00E-16,Q9ESG9,Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase),Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase),GO:0005524; GO:0000139; GO:0007049; GO:0005737; GO:0005789; GO:0046872; GO:0010923; GO:0005634; GO:0004674,ATP binding; Golgi membrane; cell cycle; cytoplasm; endoplasmic reticulum membrane; metal ion binding; negative regulation of phosphatase activity; nucleus; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PMYT1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; negative regulation of phosphatase activity [GO:0010923] comp110179_c0_seq1,259,42.8571,0.44460307,9,0,,3.00E-08,O13955,Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39),Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39),GO:0070314; GO:0030897; GO:0017112; GO:0006995; GO:0005829; GO:0000329; GO:0006886; GO:0005634; GO:0042144; GO:0048278,"G1 to G0 transition; HOPS complex; Rab guanyl-nucleotide exchange factor activity; cellular response to nitrogen starvation; cytosol; fungal-type vacuole membrane; intracellular protein transport; nucleus; vacuole fusion, non-autophagic; vesicle docking",PF00637;PF00780;PF10366;PF10367;,,,,,,,,,VAM6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"intracellular protein transport [GO:0006886]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]" comp110179_c1_seq1,397,43.5768,0.4279597,8,23,,3.00E-32,Q96JC1,Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p),Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p),GO:0030897; GO:0031902; GO:0005765; GO:0015031; GO:0005083,HOPS complex; late endosome membrane; lysosomal membrane; protein transport; small GTPase regulator activity,PF00780;PF10366;PF10367;,,,,,,,,,VPS39_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]" comp110197_c0_seq1,244,62.2951,1.23352766,2,14,,4.00E-42,Q6A7P7,4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8),4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8),GO:0008839; GO:0051287; GO:0070402; GO:0005737; GO:0019877; GO:0009089; GO:0016726,"4-hydroxy-tetrahydrodipicolinate reductase; NAD binding; NADPH binding; cytoplasm; diaminopimelate biosynthetic process; lysine biosynthetic process via diaminopimelate; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor",PF05173;PF01113;,,,,,,,,,DAPB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089] comp110199_c0_seq1,606,37.4587,0.79398516,20,16,,4.00E-17,Q0Z7S8,Fatty acid-binding protein 9 (Testis lipid-binding protein) (TLBP) (Testis-type fatty acid-binding protein) (T-FABP),Fatty acid-binding protein 9 (Testis lipid-binding protein) (TLBP) (Testis-type fatty acid-binding protein) (T-FABP),GO:0001669; GO:0001675; GO:0008289; GO:0005215,acrosomal vesicle; acrosome assembly; lipid binding; transporter activity,PF00061;,,,,,,,,,FABP9_HUMAN,Homo sapiens (Human),acrosome assembly [GO:0001675]; triglyceride catabolic process [GO:0019433] comp110207_c0_seq1,1191,47.6071,0.46794856,169,78,,2.00E-28,Q8BJH1,Zinc finger C2HC domain-containing protein 1A,Zinc finger C2HC domain-containing protein 1A,GO:0046872,metal ion binding,,7.00E-32,CHOYP_ZC21A.3.3,,,,,,,ZC21A_MOUSE,Mus musculus (Mouse), comp110230_c0_seq1,715,45.4545,0.6327531,0,0,,1.00E-07,Q8YV57,Uncharacterized WD repeat-containing protein all2124,Uncharacterized WD repeat-containing protein all2124,GO:0004197; GO:0006508,cysteine-type endopeptidase activity; proteolysis,PF12894;PF00400;,8.00E-79,CHOYP_LOC100142053.2.2,,,,,,,Y2124_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp110230_c0_seq2,905,43.0939,0.62607385,7,8,,3.00E-64,Q9QXW2,F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),GO:0080008; GO:0019005; GO:0031146; GO:0051298; GO:0005737; GO:0007067; GO:0016567,Cul4-RING ubiquitin ligase complex; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication; cytoplasm; mitosis; protein ubiquitination,PF12937;PF00400;,1.00E-78,CHOYP_LOC100142053.2.2,,,,,,,FBXW5_MOUSE,Mus musculus (Mouse),centrosome duplication [GO:0051298]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp110240_c0_seq1,210,57.1429,0.47536983,31,317,,5.00E-28,Q6UX73,UPF0764 protein C16orf89,UPF0764 protein C16orf89,GO:0005576,extracellular region,PF15882;,1.00E-18,CHOYP_RN7SL2.1.1,,,,,,,CP089_HUMAN,Homo sapiens (Human), comp110245_c0_seq1,909,41.0341,0.65512951,8,0,,8.00E-67,Q7TQE7,Uncharacterized protein KIAA0895,Uncharacterized protein KIAA0895,,,PF08014;,5.00E-58,CHOYP_BRAFLDRAFT_255724.1.1,,,,,,,K0895_MOUSE,Mus musculus (Mouse), comp110245_c2_seq1,773,37.1281,0.34400058,9,0,,4.00E-45,Q8NCT3,Uncharacterized protein KIAA0895,Uncharacterized protein KIAA0895,,,PF08014;,,,,,,,,,K0895_HUMAN,Homo sapiens (Human), comp110247_c0_seq1,1517,35.5307,0.52252597,1416,3,male>female,4.00E-12,A6QQL5,Uncharacterized protein C2orf73 homolog,Uncharacterized protein C2orf73 homolog,,,PF15667;,,,,,,,,,CB073_BOVIN,Bos taurus (Bovine), comp110250_c0_seq1,434,49.7696,0.79858803,14,27,,4.00E-16,Q6UXZ4,Netrin receptor UNC5D (Protein unc-5 homolog 4) (Protein unc-5 homolog D),Netrin receptor UNC5D (Protein unc-5 homolog 4) (Protein unc-5 homolog D),GO:0006915; GO:0007411; GO:0009986; GO:0016021; GO:0007165,apoptotic process; axon guidance; cell surface; integral to membrane; signal transduction,PF00531;PF07679;PF00090;PF00791;,,,,,,,,,UNC5D_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell-cell adhesion [GO:0098609]; pyramidal neuron differentiation [GO:0021859]; regulation of neuron migration [GO:2001222]; signal transduction [GO:0007165] comp110253_c1_seq1,393,37.659,0.29120662,10,39,,6.00E-12,Q8K3A9,7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-),7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-),GO:0008173; GO:0008757; GO:0035562; GO:0000122; GO:1900087; GO:0040031,RNA methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; negative regulation of chromatin binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of G1/S transition of mitotic cell cycle; snRNA modification,PF06859;PF13847;,,,,,,,,,MEPCE_MOUSE,Mus musculus (Mouse),negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031] comp110255_c0_seq1,441,45.5782,1.00673918,13,15,,8.00E-24,Q9R0S3,Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP),Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP),GO:0031225; GO:0005509; GO:0004222; GO:0005886; GO:0005578; GO:0006508; GO:0008270,anchored to membrane; calcium ion binding; metalloendopeptidase activity; plasma membrane; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF00045;PF00413;PF01471;,3.00E-12,CHOYP_LOC100369238.1.1,,,,,,,MMP17_MOUSE,Mus musculus (Mouse),drinking behavior [GO:0042756]; kidney development [GO:0001822] comp110257_c0_seq1,478,33.4728,0.74855774,18,374,,4.00E-17,B8JLV7,Vacuolar ATPase assembly integral membrane protein vma21,Vacuolar ATPase assembly integral membrane protein vma21,GO:0030127; GO:0005789; GO:0033116; GO:0016021; GO:0070072,COPII vesicle coat; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; vacuolar proton-transporting V-type ATPase complex assembly,PF09446;,5.00E-16,CHOYP_LOC100913633.1.1,,,,,,,VMA21_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp110270_c0_seq1,270,48.1481,1.03239511,0,12,,4.00E-30,P09172,Dopamine beta-hydroxylase (EC 1.14.17.1) (Dopamine beta-monooxygenase) [Cleaved into: Soluble dopamine beta-hydroxylase],Dopamine beta-hydroxylase (EC 1.14.17.1) (Dopamine beta-monooxygenase) [Cleaved into: Soluble dopamine beta-hydroxylase],GO:0031418; GO:0048149; GO:0001974; GO:0042423; GO:0034641; GO:0042583; GO:0034466; GO:0042584; GO:0005507; GO:0001816; GO:0004500; GO:0042420; GO:0005576; GO:0042596; GO:0042593; GO:0042309; GO:0016021; GO:0002443; GO:0050900; GO:0007626; GO:0042711; GO:0016020; GO:0007613; GO:0042421; GO:0045907; GO:0042981; GO:0042127; GO:0001975; GO:0048265; GO:0034774; GO:0044281; GO:0007268; GO:0030658; GO:0008542,L-ascorbic acid binding; behavioral response to ethanol; blood vessel remodeling; catecholamine biosynthetic process; cellular nitrogen compound metabolic process; chromaffin granule; chromaffin granule lumen; chromaffin granule membrane; copper ion binding; cytokine production; dopamine beta-monooxygenase activity; dopamine catabolic process; extracellular region; fear response; glucose homeostasis; homoiothermy; integral to membrane; leukocyte mediated immunity; leukocyte migration; locomotory behavior; maternal behavior; membrane; memory; norepinephrine biosynthetic process; positive regulation of vasoconstriction; regulation of apoptotic process; regulation of cell proliferation; response to amphetamine; response to pain; secretory granule lumen; small molecule metabolic process; synaptic transmission; transport vesicle membrane; visual learning,PF03712;PF01082;PF03351;,,,,,,,,,DOPO_HUMAN,Homo sapiens (Human),behavioral response to ethanol [GO:0048149]; blood vessel remodeling [GO:0001974]; catecholamine biosynthetic process [GO:0042423]; chemical synaptic transmission [GO:0007268]; cytokine production [GO:0001816]; dopamine catabolic process [GO:0042420]; fear response [GO:0042596]; glucose homeostasis [GO:0042593]; homoiothermy [GO:0042309]; leukocyte mediated immunity [GO:0002443]; leukocyte migration [GO:0050900]; locomotory behavior [GO:0007626]; maternal behavior [GO:0042711]; memory [GO:0007613]; norepinephrine biosynthetic process [GO:0042421]; positive regulation of vasoconstriction [GO:0045907]; regulation of cell proliferation [GO:0042127]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; response to amphetamine [GO:0001975]; response to pain [GO:0048265]; visual learning [GO:0008542] comp110272_c0_seq1,857,44.4574,0.42804936,19,65,,6.00E-23,Q4V8R6,Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),GO:0003677; GO:0051301; GO:0005737; GO:0016874; GO:0046872; GO:0007067; GO:0005654; GO:0016567; GO:0040008; GO:0006355; GO:0006351,"DNA binding; cell division; cytoplasm; ligase activity; metal ion binding; mitosis; nucleoplasm; protein ubiquitination; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,E4F1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp110281_c0_seq1,437,46.6819,0.50519296,35,23,,6.00E-09,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,,,,,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp110286_c0_seq1,328,41.7683,0.28059962,4,5,,1.00E-11,Q6IR74,Choline transporter-like protein 1 (Solute carrier family 44 member 1),Choline transporter-like protein 1 (Solute carrier family 44 member 1),GO:0016021,integral to membrane,PF04515;,,,,,,,,,CTL1_XENLA,Xenopus laevis (African clawed frog), comp110286_c1_seq1,1027,43.8169,0.51349726,29,44,,5.00E-55,Q7Q5R7,CTL-like protein 1,CTL-like protein 1,GO:0016021,integral to membrane,PF04515;,3.00E-29,CHOYP_BRAFLDRAFT_130395.1.1,,,,,,,CTLH1_ANOGA,Anopheles gambiae (African malaria mosquito), comp110294_c0_seq1,755,43.8411,0.67175238,18,35,,9.00E-69,Q4VSN1,Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),GO:0005524; GO:0005737; GO:0018108; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00069;,1.00E-38,CHOYP_NEMVEDRAFT_V1G241055.1.1,,,,,,,DUSTY_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic organ development [GO:0048568]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp110297_c0_seq2,436,36.4679,0.15032759,4,20,,1.00E-15,Q6XJU9,Osteoclast-stimulating factor 1 (Osteoclast-stimulating factor-like),Osteoclast-stimulating factor 1 (Osteoclast-stimulating factor-like),GO:0005737,cytoplasm,PF12796;PF00018;,6.00E-21,CHOYP_LOC100366488.1.1,,,,,,,OSTF1_MONAL,Monopterus albus (Swamp eel), comp110314_c0_seq1,280,45,0.65047126,9,16,,3.00E-06,Q5R6S5,Hippocalcin-like protein 4,Hippocalcin-like protein 4,GO:0005509; GO:0005622,calcium ion binding; intracellular,PF00036;PF13499;,,,,,,,,,HPCL4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),signal transduction [GO:0007165] comp110314_c1_seq1,673,42.9421,0.55892806,25,38,,5.00E-66,Q8NFA0,Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),GO:0005794; GO:0005509; GO:0008234; GO:0016020; GO:0016579; GO:0004221; GO:0006511,Golgi apparatus; calcium ion binding; cysteine-type peptidase activity; membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF06337;PF13202;PF14836;PF00443;,4.00E-32,CHOYP_UBP32.1.1,,,,,,,UBP32_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp110334_c0_seq1,990,35.0505,0.53574862,31,122,,5.00E-09,Q99JY1,Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein),Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein),GO:0070935; GO:0007249; GO:0007257; GO:0007166; GO:0071221; GO:0071223; GO:0050830; GO:0030139; GO:0006954; GO:0045087; GO:0030099; GO:0044130; GO:0005546; GO:0030890; GO:0070374; GO:0046330; GO:0051092; GO:2000340; GO:2000343; GO:0045089; GO:0032735; GO:0045410; GO:0032757; GO:0090023; GO:0034137; GO:0034141; GO:0034145; GO:0032760; GO:0046982; GO:0042803; GO:0005080; GO:0032648; GO:0032658; GO:0032496; GO:0032587,"3'-UTR-mediated mRNA stabilization; I-kappaB kinase/NF-kappaB cascade; activation of JUN kinase activity; cell surface receptor signaling pathway; cellular response to bacterial lipopeptide; cellular response to lipoteichoic acid; defense response to Gram-positive bacterium; endocytic vesicle; inflammatory response; innate immune response; myeloid cell differentiation; negative regulation of growth of symbiont in host; phosphatidylinositol-4,5-bisphosphate binding; positive regulation of B cell proliferation; positive regulation of ERK1 and ERK2 cascade; positive regulation of JNK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of chemokine (C-X-C motif) ligand 1 production; positive regulation of chemokine (C-X-C motif) ligand 2 production; positive regulation of innate immune response; positive regulation of interleukin-12 production; positive regulation of interleukin-6 biosynthetic process; positive regulation of interleukin-8 production; positive regulation of neutrophil chemotaxis; positive regulation of toll-like receptor 2 signaling pathway; positive regulation of toll-like receptor 3 signaling pathway; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of tumor necrosis factor production; protein heterodimerization activity; protein homodimerization activity; protein kinase C binding; regulation of interferon-beta production; regulation of interleukin-15 production; response to lipopolysaccharide; ruffle membrane",PF13676;,,,,,,,,,TIRAP_MOUSE,Mus musculus (Mouse),3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of JUN kinase activity [GO:0007257]; cell surface receptor signaling pathway [GO:0007166]; cellular response to bacterial lipopeptide [GO:0071221]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-positive bacterium [GO:0050830]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000340]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-15 production [GO:0032738]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of innate immune response [GO:0045088]; regulation of interferon-beta production [GO:0032648]; regulation of interleukin-15 production [GO:0032658]; response to bacterium [GO:0009617]; response to lipopolysaccharide [GO:0032496]; TIRAP-dependent toll-like receptor 4 signaling pathway [GO:0035665] comp110338_c0_seq1,624,44.2308,0.45968072,13,33,,3.00E-36,Q96Q05,Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein),Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein),GO:0005794; GO:0030154; GO:0005783,Golgi apparatus; cell differentiation; endoplasmic reticulum,PF08626;,,,,,,,,,TPPC9_HUMAN,Homo sapiens (Human),cerebral cortex development [GO:0021987]; COPII vesicle coating [GO:0048208]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092] comp110338_c0_seq2,405,47.1605,0.58230717,0,0,,1.00E-28,Q96Q05,Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein),Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein),GO:0005794; GO:0030154; GO:0005783,Golgi apparatus; cell differentiation; endoplasmic reticulum,PF08626;,,,,,,,,,TPPC9_HUMAN,Homo sapiens (Human),cerebral cortex development [GO:0021987]; COPII vesicle coating [GO:0048208]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092] comp110339_c0_seq1,313,41.5335,0.37381334,4,5,,,,,,,,,,,9.00E-15,ruditapes_c12888,,,,,,, comp110348_c0_seq1,917,41.5485,0.63275509,32,46,,3.00E-21,Q9Y6I9,Testis-expressed sequence 264 protein (Putative secreted protein Zsig11),Testis-expressed sequence 264 protein (Putative secreted protein Zsig11),GO:0005576,extracellular region,,,,,,,,,,TX264_HUMAN,Homo sapiens (Human), comp110351_c0_seq1,238,38.6555,0.33949463,2,34,,,,,,,,,,,1.00E-11,ruditapes_c7836,,,,,,, comp110352_c0_seq1,584,36.9863,0.3152232,15,41,,7.00E-37,Q6NRQ1,"UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 (Beta-1,3-GalNAc-T2) (EC 2.4.1.-) (Beta-1,3-N-acetylgalactosaminyltransferase II)","UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 (Beta-1,3-GalNAc-T2) (EC 2.4.1.-) (Beta-1,3-N-acetylgalactosaminyltransferase II)",GO:0000139; GO:0008376; GO:0008375; GO:0005783; GO:0008378; GO:0016021; GO:0006493,Golgi membrane; acetylgalactosaminyltransferase activity; acetylglucosaminyltransferase activity; endoplasmic reticulum; galactosyltransferase activity; integral to membrane; protein O-linked glycosylation,PF01762;,,,,,,,,,B3GL2_XENLA,Xenopus laevis (African clawed frog),protein glycosylation [GO:0006486]; protein O-linked glycosylation [GO:0006493] comp110357_c0_seq1,406,36.4532,0.74338351,6,48,,2.00E-36,Q969X5,Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32),Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32),GO:0006888; GO:0000139; GO:0005789; GO:0005793; GO:0033116; GO:0016021,ER to Golgi vesicle-mediated transport; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane,PF07970;,2.00E-19,CHOYP_ERGI1.1.1,,,,,,,ERGI1_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888] comp110366_c0_seq1,1212,43.6469,0.41705375,58,146,,5.00E-79,Q6PGC1,ATP-dependent RNA helicase Dhx29 (EC 3.6.4.13) (DEAH box protein 29),ATP-dependent RNA helicase Dhx29 (EC 3.6.4.13) (DEAH box protein 29),GO:0005524; GO:0008026; GO:0016282; GO:0005739; GO:0043024; GO:0003743,ATP binding; ATP-dependent helicase activity; eukaryotic 43S preinitiation complex; mitochondrion; ribosomal small subunit binding; translation initiation factor activity,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX29_MOUSE,Mus musculus (Mouse),RNA processing [GO:0006396] comp110385_c0_seq1,387,45.9948,0.50620038,28,8,,1.00E-27,O93574,Reelin (EC 3.4.21.-) (Fragment),Reelin (EC 3.4.21.-) (Fragment),GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0005615; GO:0010001; GO:0046872; GO:0001764; GO:0018108; GO:0045860; GO:0051057; GO:0004712; GO:0005578; GO:0006508; GO:0048265; GO:0008236; GO:0021511; GO:0021517,axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; extracellular space; glial cell differentiation; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of protein kinase activity; positive regulation of small GTPase mediated signal transduction; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development,PF07974;PF12661;,,,,,,,,,RELN_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517] comp110389_c0_seq1,856,42.8738,0.35922205,41,36,,3.00E-70,Q61586,"Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15) (P90)","Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15) (P90)",GO:0016024; GO:0006637; GO:0051607; GO:0055089; GO:0006631; GO:0004366; GO:0006650; GO:0016021; GO:0070970; GO:0005743; GO:0005741; GO:0070236; GO:0055091; GO:0005886; GO:0042104; GO:0040018; GO:0050707; GO:0009749; GO:0019432; GO:0006641,CDP-diacylglycerol biosynthetic process; acyl-CoA metabolic process; defense response to virus; fatty acid homeostasis; fatty acid metabolic process; glycerol-3-phosphate O-acyltransferase activity; glycerophospholipid metabolic process; integral to membrane; interleukin-2 secretion; mitochondrial inner membrane; mitochondrial outer membrane; negative regulation of activation-induced cell death of T cells; phospholipid homeostasis; plasma membrane; positive regulation of activated T cell proliferation; positive regulation of multicellular organism growth; regulation of cytokine secretion; response to glucose stimulus; triglyceride biosynthetic process; triglyceride metabolic process,PF01553;,,,,,,,,,GPAT1_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; cellular response to insulin stimulus [GO:0032869]; defense response to virus [GO:0051607]; fatty acid homeostasis [GO:0055089]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; interleukin-2 secretion [GO:0070970]; negative regulation of activation-induced cell death of T cells [GO:0070236]; phospholipid homeostasis [GO:0055091]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cytokine secretion [GO:0050707]; response to activity [GO:0014823]; response to cadmium ion [GO:0046686]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to nutrient levels [GO:0031667]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641] comp110394_c0_seq2,356,46.6292,0.77733231,3,0,,3.00E-08,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp110400_c0_seq1,1337,41.5856,0.32909608,195,1583,,4.00E-36,Q8BGA7,Uncharacterized protein C7orf26 homolog,Uncharacterized protein C7orf26 homolog,,,PF14964;,2.00E-15,CHOYP_BRAFLDRAFT_93665.1.1,,,,,,,CG026_MOUSE,Mus musculus (Mouse), comp110403_c1_seq1,205,44.3902,0.49759638,1,9,,7.00E-11,B1H2Q6,Zinc finger protein 865,Zinc finger protein 865,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN865_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp110410_c0_seq2,664,47.1386,0.52098914,23,0,,2.00E-21,P59240,Nephrocystin-4 (Nephroretinin),Nephrocystin-4 (Nephroretinin),GO:0005911; GO:0005813; GO:0005929; GO:0005737; GO:0005932; GO:0060041; GO:0005923,cell-cell junction; centrosome; cilium; cytoplasm; microtubule basal body; retina development in camera-type eye; tight junction,,,,,,,,,,NPHP4_MOUSE,Mus musculus (Mouse),negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317] comp110411_c1_seq1,812,43.3498,0.50283279,31,9,,1.00E-49,Q5SUS0,F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10),F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10),,,PF00400;,1.00E-21,CHOYP_LOC589839.1.1,,,,,,,FBW10_MOUSE,Mus musculus (Mouse), comp110417_c0_seq1,345,38.2609,0.54246602,5,15,,5.00E-06,Q8C3K5,Transmembrane protein 72,Transmembrane protein 72,GO:0016021,integral to membrane,PF16054;,,,,,,,,,TMM72_MOUSE,Mus musculus (Mouse), comp110437_c0_seq1,497,48.2897,0.69340297,13,24,,5.00E-34,Q8BND5,Sulfhydryl oxidase 1 (mSOx) (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase),Sulfhydryl oxidase 1 (mSOx) (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase),GO:0045454; GO:0005783; GO:0005615; GO:0016971; GO:0030173; GO:0003756,cell redox homeostasis; endoplasmic reticulum; extracellular space; flavin-linked sulfhydryl oxidase activity; integral to Golgi membrane; protein disulfide isomerase activity,PF04777;PF00085;,,,,,,,,,QSOX1_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; negative regulation of macroautophagy [GO:0016242]; protein folding [GO:0006457] comp110443_c0_seq1,702,43.3048,0.55113352,51,14,,4.00E-10,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp110469_c0_seq1,825,40.8485,1.38671737,61,911,,9.00E-07,P37806,Protein unc-87 (Uncoordinated protein 87),Protein unc-87 (Uncoordinated protein 87),GO:0031674; GO:0051015; GO:0051017; GO:0001725; GO:0005865,I band; actin filament binding; actin filament bundle assembly; stress fiber; striated muscle thin filament,PF00402;,,,5.00E-30,ruditapes_lrc35701,,,,,UNC87_CAEEL,Caenorhabditis elegans,actin filament bundle assembly [GO:0051017]; actomyosin structure organization [GO:0031032]; myosin filament assembly [GO:0031034]; negative regulation of muscle filament sliding [GO:1904113]; negative regulation of plus-end directed microfilament motor activity [GO:1904111] comp110477_c0_seq1,213,44.1315,0.32359584,3,15,,5.00E-14,Q8IW92,Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),GO:0004565; GO:0005975; GO:0005576,beta-galactosidase activity; carbohydrate metabolic process; extracellular region,PF01301;,,,,,,,,,GLBL2_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975] comp110477_c1_seq1,425,40.9412,0,3,25,,9.00E-12,Q8NCI6,Beta-galactosidase-1-like protein 3 (EC 3.2.1.-),Beta-galactosidase-1-like protein 3 (EC 3.2.1.-),GO:0004565; GO:0005975,beta-galactosidase activity; carbohydrate metabolic process,PF01301;,,,,,,,,,GLBL3_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975] comp110516_c0_seq1,622,48.2315,0.83100121,15,55,,1.00E-18,Q6DFU2,Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog),Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog),GO:0005737; GO:0005856; GO:0005634,cytoplasm; cytoskeleton; nucleus,PF07707;PF00651;PF01344;,,,,,,,,,NS1BP_XENLA,Xenopus laevis (African clawed frog), comp110570_c0_seq1,618,46.2783,0.34347346,7,66,,1.00E-41,Q91W90,Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46),Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46),GO:0045454; GO:0005788; GO:0006662; GO:0016853; GO:0015035,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; isomerase activity; protein disulfide oxidoreductase activity,PF00085;,,,,,,,,,TXND5_MOUSE,Mus musculus (Mouse),apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp110573_c0_seq1,1067,41.9869,0.55528275,0,3,,8.00E-25,Q9Y4G8,Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),GO:0000165; GO:0030165; GO:0046582; GO:0017034; GO:0032486; GO:0050699; GO:0071880; GO:0031697; GO:0001568; GO:0031547; GO:0030552; GO:0019933; GO:0005509; GO:0005911; GO:0071320; GO:0071321; GO:0019992; GO:0061028; GO:0021884; GO:0005887; GO:0005770; GO:0008285; GO:0050774; GO:0048022; GO:0038180; GO:0001764; GO:0043005; GO:0031175; GO:0043025; GO:0007218; GO:0048471; GO:0070374; GO:2000481; GO:0043950; GO:2000670; GO:2001224; GO:0010976; GO:0032092; GO:2001214; GO:0043234; GO:1901888; GO:0048167; GO:0004871; GO:0045202; GO:0021591,MAPK cascade; PDZ domain binding; Rap GTPase activator activity; Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; WW domain binding; adenylate cyclase-activating adrenergic receptor signaling pathway; beta-1 adrenergic receptor binding; blood vessel development; brain-derived neurotrophic factor receptor signaling pathway; cAMP binding; cAMP-mediated signaling; calcium ion binding; cell-cell junction; cellular response to cAMP; cellular response to cGMP; diacylglycerol binding; establishment of endothelial barrier; forebrain neuron development; integral to plasma membrane; late endosome; negative regulation of cell proliferation; negative regulation of dendrite morphogenesis; negative regulation of melanin biosynthetic process; nerve growth factor signaling pathway; neuron migration; neuron projection; neuron projection development; neuronal cell body; neuropeptide signaling pathway; perinuclear region of cytoplasm; positive regulation of ERK1 and ERK2 cascade; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cAMP-mediated signaling; positive regulation of dendritic cell apoptotic process; positive regulation of neuron migration; positive regulation of neuron projection development; positive regulation of protein binding; positive regulation of vasculogenesis; protein complex; regulation of cell junction assembly; regulation of synaptic plasticity; signal transducer activity; synapse; ventricular system development,PF00595;PF00788;PF00617;PF00618;,,,,,,,,,RPGF2_HUMAN,Homo sapiens (Human),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microvillus assembly [GO:0030033]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; small GTPase mediated signal transduction [GO:0007264]; ventricular system development [GO:0021591] comp110573_c0_seq2,1363,43.1401,0.58502124,2,58,,3.00E-165,Q28EC1,Ras-GEF domain-containing family member 1B,Ras-GEF domain-containing family member 1B,GO:0005088; GO:0005622; GO:0051056; GO:0007264,Ras guanyl-nucleotide exchange factor activity; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00617;PF00618;,3.00E-163,CHOYP_RG1BA.1.1,,,,,,,RGF1B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),small GTPase mediated signal transduction [GO:0007264] comp110575_c0_seq1,2023,42.3134,0.62159791,65,120,,2.00E-78,Q9YGN6,Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-),Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-),GO:0003677; GO:0006281; GO:0016798; GO:0005634,"DNA binding; DNA repair; hydrolase activity, acting on glycosyl bonds; nucleus",,3.00E-13,CHOYP_NEMVEDRAFT_V1G158158.1.1,,,,,,,SMUG1_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281] comp110578_c0_seq2,725,44.9655,0.32890428,12,14,,1.00E-134,Q8R1F6,Protein HID1 (HID1 domain-containing protein) (Protein hid-1 homolog),Protein HID1 (HID1 domain-containing protein) (Protein hid-1 homolog),GO:0005797; GO:0000138; GO:0005881; GO:0090498; GO:0006886; GO:0005886; GO:0031001,Golgi medial cisterna; Golgi trans cisterna; cytoplasmic microtubule; extrinsic to Golgi membrane; intracellular protein transport; plasma membrane; response to brefeldin A,,9.00E-174,CHOYP_LOC100374703.1.1,,,,,,,HID1_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; response to brefeldin A [GO:0031001] comp110590_c0_seq1,630,44.127,0.47127353,24,69,,2.00E-41,Q9GKS9,Double zinc ribbon and ankyrin repeat-containing protein 1,Double zinc ribbon and ankyrin repeat-containing protein 1,GO:0008270,zinc ion binding,PF12773;,3.00E-58,CHOYP_LOC100366424.1.1,,,,,,,DZAN1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp110590_c1_seq1,225,48,0.81531192,4,10,,2.00E-06,A8MQB9,Putative ankyrin repeat domain-containing protein ENSP00000330211,,,,,,,,,,,,,YR007_HUMAN,, comp110593_c1_seq1,634,42.9022,0.39696621,17,30,,8.00E-72,Q9DGG6,Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9),Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9),GO:0005524; GO:0004016; GO:0016021; GO:0035556; GO:0046872,ATP binding; adenylate cyclase activity; integral to membrane; intracellular signal transduction; metal ion binding,PF00211;,3.00E-71,CHOYP_APLD.1.1,,,,,,,ADCY9_CHICK,Gallus gallus (Chicken),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933] comp110595_c0_seq1,788,39.8477,0.41612303,0,0,,3.00E-15,Q8AVI4,Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog),Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog),GO:0005634; GO:0046579; GO:0019903; GO:0000164,nucleus; positive regulation of Ras protein signal transduction; protein phosphatase binding; protein phosphatase type 1 complex,PF13855;,,,,,,,,,SHOC2_XENLA,Xenopus laevis (African clawed frog),positive regulation of Ras protein signal transduction [GO:0046579] comp110595_c0_seq2,897,40.2453,0.41359668,7,0,,4.00E-15,Q8AVI4,Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog),Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog),GO:0005634; GO:0046579; GO:0019903; GO:0000164,nucleus; positive regulation of Ras protein signal transduction; protein phosphatase binding; protein phosphatase type 1 complex,PF13855;,,,,,,,,,SHOC2_XENLA,Xenopus laevis (African clawed frog),positive regulation of Ras protein signal transduction [GO:0046579] comp110599_c0_seq1,367,43.8692,0.68465625,14,7,,7.00E-08,Q6P7A2,Ubiquitin conjugation factor E4 A,Ubiquitin conjugation factor E4 A (EC 6.3.2.-),GO:0000151; GO:0006511; GO:0034450,ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-ubiquitin ligase activity,PF04564;PF10408;,,,,,,,,,UBE4A_RAT,Rattus norvegicus (Rat),ubiquitin-dependent protein catabolic process [GO:0006511] comp110600_c0_seq1,560,39.4643,0.18746927,14,73,,3.00E-15,O00519,Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1),Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1),GO:0047372; GO:0016884; GO:0005737; GO:0005856; GO:0012505; GO:0017064; GO:0009062; GO:0016021; GO:0031090,"acylglycerol lipase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; cytoplasm; cytoskeleton; endomembrane system; fatty acid amide hydrolase activity; fatty acid catabolic process; integral to membrane; organelle membrane",PF01425;,9.00E-14,CHOYP_LOC100712443.1.1,,,,,,,FAAH1_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; fatty acid catabolic process [GO:0009062] comp110601_c0_seq2,458,47.1616,0.5547812,5,4,,5.00E-29,Q91ZI0,Cadherin EGF LAG seven-pass G-type receptor 3,Cadherin EGF LAG seven-pass G-type receptor 3,GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_MOUSE,Mus musculus (Mouse),axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp110603_c0_seq1,1106,45.2984,0.50043633,29,86,,2.00E-140,Q8N3P4,Vacuolar protein sorting-associated protein 8 homolog,Vacuolar protein sorting-associated protein 8 homolog,GO:0008270,zinc ion binding,PF12816;,3.00E-119,CHOYP_VPS8.1.1,,,,,,,VPS8_HUMAN,Homo sapiens (Human),endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031] comp110607_c0_seq1,359,35.9331,0.43583873,1,34,,8.00E-20,Q5E9Q1,Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1),Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase) (EC 2.4.2.26),GO:0035251; GO:0035252; GO:0072358; GO:0005788; GO:0006493; GO:0008593,UDP-glucosyltransferase activity; UDP-xylosyltransferase activity; cardiovascular system development; endoplasmic reticulum lumen; protein O-linked glycosylation; regulation of Notch signaling pathway,PF05686;,2.00E-27,CHOYP_POGLUT1.1.1,,,,,,,PGLT1_BOVIN,Bos taurus (Bovine),cardiovascular system development [GO:0072358]; glycolipid metabolic process [GO:0006664]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493] comp110621_c1_seq1,721,43.1345,0.44811407,27,5,,3.00E-34,Q07113,Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),GO:0009986; GO:0030139; GO:0005768; GO:0001948; GO:0016021; GO:0005765; GO:0005537; GO:0016020; GO:0005641; GO:0051219; GO:0030140; GO:0005215,cell surface; endocytic vesicle; endosome; glycoprotein binding; integral to membrane; lysosomal membrane; mannose binding; membrane; nuclear envelope lumen; phosphoprotein binding; trans-Golgi network transport vesicle; transporter activity,PF00878;PF00040;,,,,,,,,,MPRI_MOUSE,Mus musculus (Mouse),liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; response to retinoic acid [GO:0032526]; spermatogenesis [GO:0007283] comp110622_c0_seq1,263,37.2624,0.33333815,3,79,,3.00E-12,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp110626_c0_seq1,501,36.7265,0.49562088,10,133,,3.00E-44,Q29AU5,Mitochondrial GTPase 1,Mitochondrial GTPase 1,GO:0005525; GO:0005739,GTP binding; mitochondrion,PF01926;,,,,,,,,,MTG1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp110626_c1_seq1,330,41.2121,0.64930849,2,38,,1.00E-15,C5D8U8,Ribosome biogenesis GTPase A,Ribosome biogenesis GTPase A,GO:0005525; GO:0003723; GO:0005737; GO:0016787; GO:0042254,GTP binding; RNA binding; cytoplasm; hydrolase activity; ribosome biogenesis,PF01926;,,,,,,,,,RBGA_GEOSW,Geobacillus sp. (strain WCH70),ribosome biogenesis [GO:0042254] comp110629_c0_seq1,1073,47.2507,0.86038842,51,21,,3.00E-09,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,1.00E-16,CHOYP_LOC100367237.2.2,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp110650_c0_seq1,246,74.7967,1.10908131,0,6,,4.00E-31,Q21XQ9,Porphobilinogen deaminase (PBG) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase),Porphobilinogen deaminase (PBG) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase),GO:0004418; GO:0006782,hydroxymethylbilane synthase activity; protoporphyrinogen IX biosynthetic process,PF01379;PF03900;,,,,,,,,,HEM3_RHOFD,Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens),protoporphyrinogen IX biosynthetic process [GO:0006782] comp110655_c0_seq1,637,41.4443,0.88386272,25,3,,6.00E-19,P49883,Ecdysone receptor (20-hydroxy-ecdysone receptor) (20E receptor) (EcRH) (Ecdysteroid receptor) (Nuclear receptor subfamily 1 group H member 1),Ecdysone receptor (20-hydroxy-ecdysone receptor) (20E receptor) (EcRH) (Ecdysteroid receptor) (Nuclear receptor subfamily 1 group H member 1),GO:0004884; GO:0005634; GO:0043565; GO:0005496; GO:0008270,ecdysteroid hormone receptor activity; nucleus; sequence-specific DNA binding; steroid binding; zinc ion binding,PF00104;PF00105;,4.00E-13,CHOYP_ECR.1.1,,,,,,,ECR_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),"transcription, DNA-templated [GO:0006351]" comp110675_c0_seq1,441,39.0023,0.72508917,0,0,,,,,,,,,2.00E-26,CHOYP_VPP1.2.2,,,,,,,,, comp110675_c0_seq5,1225,42.0408,0.51776807,25,32,,3.00E-119,P25286,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,8.00E-44,CHOYP_LOC100741247.2.2,7.00E-11,ruditapes_c28582,,,,,VPP1_RAT,Rattus norvegicus (Rat),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp110681_c0_seq1,481,43.8669,0.65029963,7,37,,5.00E-58,Q8IWF2,FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),GO:0030433; GO:0005788; GO:0050660; GO:0016491,ER-associated protein catabolic process; endoplasmic reticulum lumen; flavin adenine dinucleotide binding; oxidoreductase activity,,2.00E-41,CHOYP_HX1.1.1,,,,,,,FXRD2_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114] comp110691_c0_seq1,797,45.6713,0.56020599,51,51,,8.00E-93,O95405,Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation),Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation),GO:0005545; GO:0007183; GO:0007184; GO:0031901; GO:0006897; GO:0046872; GO:0030512; GO:0008236; GO:0007179,1-phosphatidylinositol binding; SMAD protein complex assembly; SMAD protein import into nucleus; early endosome membrane; endocytosis; metal ion binding; negative regulation of transforming growth factor beta receptor signaling pathway; serine-type peptidase activity; transforming growth factor beta receptor signaling pathway,PF11979;PF01363;PF11409;,2.00E-56,CHOYP_LOC575625.2.2,,,,,,,ZFYV9_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; SMAD protein complex assembly [GO:0007183]; SMAD protein import into nucleus [GO:0007184]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp110707_c0_seq1,362,53.3149,0.35174687,17,7,,,,,,,,,1.00E-53,CHOYP_BRAFLDRAFT_120904.1.1,,,,,,,,, comp110709_c0_seq1,1148,40.9408,0.46583406,11,152,,4.00E-57,Q7SZ73,F-box/LRR-repeat protein 15,F-box/LRR-repeat protein 15,GO:0000086; GO:0019005; GO:0031146; GO:0030282; GO:0005737; GO:0009953; GO:0030513; GO:0016567,G2/M transition of mitotic cell cycle; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; bone mineralization; cytoplasm; dorsal/ventral pattern formation; positive regulation of BMP signaling pathway; protein ubiquitination,PF00646;PF13516;,,,,,,,,,FXL15_XENLA,Xenopus laevis (African clawed frog),bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp110715_c0_seq1,424,41.5094,0.27615488,12,12,,4.00E-28,Q5VU97,VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1),VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1),GO:0006816; GO:0016021,calcium ion transport; integral to membrane,PF00092;PF08399;,,,,,,,,,CAHD1_HUMAN,Homo sapiens (Human),calcium ion transport [GO:0006816] comp110717_c0_seq1,540,40,1.08777364,10,99,,2.00E-07,Q9WTR0,Matrix metalloproteinase-16 (MMP-16) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP),Matrix metalloproteinase-16 (MMP-16) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP),GO:0005509; GO:0030574; GO:0031012; GO:0016021; GO:0004222; GO:0005886; GO:0006508; GO:0008270,calcium ion binding; collagen catabolic process; extracellular matrix; integral to membrane; metalloendopeptidase activity; plasma membrane; proteolysis; zinc ion binding,PF11857;PF00045;PF00413;PF01471;,,,,,,,,,MMP16_MOUSE,Mus musculus (Mouse),bone development [GO:0060348]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; ossification [GO:0001503] comp110717_c1_seq1,242,41.7355,1.19510237,5,19,,7.00E-16,P29788,Vitronectin (VN) (S-protein) (Serum-spreading factor),Vitronectin (VN) (S-protein) (Serum-spreading factor),GO:0033627; GO:0007160; GO:0050840; GO:0030198; GO:0005615; GO:0008201; GO:0006955; GO:0010951; GO:0030247; GO:0010811; GO:0050731; GO:0032092; GO:0048260; GO:0014911; GO:0005578; GO:0005044; GO:0061302,cell adhesion mediated by integrin; cell-matrix adhesion; extracellular matrix binding; extracellular matrix organization; extracellular space; heparin binding; immune response; negative regulation of endopeptidase activity; polysaccharide binding; positive regulation of cell-substrate adhesion; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein binding; positive regulation of receptor-mediated endocytosis; positive regulation of smooth muscle cell migration; proteinaceous extracellular matrix; scavenger receptor activity; smooth muscle cell-matrix adhesion,PF00045;PF01033;,,,,,,,,,VTNC_MOUSE,Mus musculus (Mouse),cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; negative regulation of endopeptidase activity [GO:0010951]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of smooth muscle cell migration [GO:0014911]; smooth muscle cell-matrix adhesion [GO:0061302] comp110722_c0_seq1,284,44.3662,0.43982027,13,12,,4.00E-17,Q1LUI2,HD domain-containing protein 2,HD domain-containing protein 2,GO:0008152; GO:0046872; GO:0008081,metabolic process; metal ion binding; phosphoric diester hydrolase activity,PF13023;,,,1.00E-32,ruditapes_c8565,,,,,HDDC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp110726_c0_seq1,404,58.4158,0.84375517,0,57,,1.00E-05,Q1L8P7,Thrombospondin-3b (Thbs3b),Thrombospondin-3b (Thbs3b),GO:0005509; GO:0007155; GO:0005576,calcium ion binding; cell adhesion; extracellular region,PF11598;PF07645;PF02412;PF05735;,,,,,,,,,TSP3B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155] comp110730_c0_seq1,225,63.1111,1.12440032,1,8,,5.00E-41,Q6A780,Error-prone DNA polymerase (EC 2.7.7.7),Error-prone DNA polymerase (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0006281; GO:0006260; GO:0003887; GO:0005737,3'-5' exonuclease activity; DNA binding; DNA repair; DNA replication; DNA-directed DNA polymerase activity; cytoplasm,PF07733;PF14579;PF02811;PF01336;,,,,,,,,,DNAE2_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA repair [GO:0006281]; DNA replication [GO:0006260] comp110736_c0_seq1,847,40.9681,0.592416,0,9,,4.00E-13,P51140,Segment polarity protein dishevelled,Segment polarity protein dishevelled,GO:0005112; GO:0007464; GO:0060071; GO:0005912; GO:0048675; GO:0007298; GO:0005938; GO:0007394; GO:0048730; GO:0045198; GO:0090163; GO:0001737; GO:0048106; GO:0008585; GO:0046847; GO:0060914; GO:0035556; GO:0030032; GO:0008045; GO:0003136; GO:0005634; GO:0016318; GO:0070300; GO:0005886; GO:0008104; GO:0032231; GO:0048076; GO:0035159; GO:0031290; GO:0007435; GO:0007367; GO:0004871; GO:0035019; GO:0016201; GO:0035309,"Notch binding; R3/R4 cell fate commitment; Wnt receptor signaling pathway, planar cell polarity pathway; adherens junction; axon extension; border follicle cell migration; cell cortex; dorsal closure, elongation of leading edge cells; epidermis morphogenesis; establishment of epithelial cell apical/basal polarity; establishment of epithelial cell planar polarity; establishment of imaginal disc-derived wing hair orientation; establishment of thoracic bristle planar orientation; female gonad development; filopodium assembly; heart formation; intracellular signal transduction; lamellipodium assembly; motor neuron axon guidance; negative regulation of heart induction by canonical Wnt receptor signaling pathway; nucleus; ommatidial rotation; phosphatidic acid binding; plasma membrane; protein localization; regulation of actin filament bundle assembly; regulation of compound eye pigmentation; regulation of tube length, open tracheal system; retinal ganglion cell axon guidance; salivary gland morphogenesis; segment polarity determination; signal transducer activity; somatic stem cell maintenance; synaptic target inhibition; wing and notum subfield formation",PF00610;PF02377;PF00778;PF00595;,6.00E-18,CHOYP_LOC100377347.1.1,,,,,,,DSH_DROME,Drosophila melanogaster (Fruit fly),"axon extension [GO:0048675]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell migration [GO:0016477]; compound eye morphogenesis [GO:0001745]; dorsal closure [GO:0007391]; dorsal closure, elongation of leading edge cells [GO:0007394]; epidermis morphogenesis [GO:0048730]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of epithelial cell planar polarity [GO:0090163]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of mitotic spindle orientation [GO:0000132]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of thoracic bristle planar orientation [GO:0048106]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of cell polarity [GO:0007163]; female gonad development [GO:0008585]; filopodium assembly [GO:0046847]; heart development [GO:0007507]; heart formation [GO:0060914]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; motor neuron axon guidance [GO:0008045]; negative regulation of heart induction by canonical Wnt signaling pathway [GO:0003136]; negative regulation of Notch signaling pathway [GO:0045746]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; protein localization [GO:0008104]; R3/R4 cell fate commitment [GO:0007464]; regulation of actin filament bundle assembly [GO:0032231]; regulation of compound eye pigmentation [GO:0048076]; regulation of tube length, open tracheal system [GO:0035159]; retinal ganglion cell axon guidance [GO:0031290]; salivary gland morphogenesis [GO:0007435]; segment polarity determination [GO:0007367]; sensory organ development [GO:0007423]; somatic stem cell population maintenance [GO:0035019]; synaptic target inhibition [GO:0016201]; wing and notum subfield formation [GO:0035309]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp110736_c0_seq3,2095,43.5322,0.516027,27,65,,2.00E-67,Q2VUH7,Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1),Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1),GO:0043679; GO:0043010; GO:0060070; GO:0005938; GO:0007049; GO:0021695; GO:0021799; GO:0005829; GO:0005925; GO:0030900; GO:0021869; GO:0043015; GO:0031435; GO:0045665; GO:0043025; GO:0046330; GO:0050772; GO:0090263; GO:0043234; GO:0032956; GO:0070507; GO:0004871,axon terminus; camera-type eye development; canonical Wnt receptor signaling pathway; cell cortex; cell cycle; cerebellar cortex development; cerebral cortex radially oriented cell migration; cytosol; focal adhesion; forebrain development; forebrain ventricular zone progenitor cell division; gamma-tubulin binding; mitogen-activated protein kinase kinase kinase binding; negative regulation of neuron differentiation; neuronal cell body; positive regulation of JNK cascade; positive regulation of axonogenesis; positive regulation of canonical Wnt receptor signaling pathway; protein complex; regulation of actin cytoskeleton organization; regulation of microtubule cytoskeleton organization; signal transducer activity,PF00307;PF00778;,2.00E-28,CHOYP_LOC100377347.1.1,,,,,,,DIXC1_RAT,Rattus norvegicus (Rat),canonical Wnt signaling pathway [GO:0060070]; cerebellar cortex development [GO:0021695]; positive regulation of axonogenesis [GO:0050772]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330] comp110761_c1_seq1,895,41.8994,0.53938836,21,74,,4.00E-22,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,9.00E-29,CHOYP_UBP24.1.1,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp110772_c1_seq2,419,47.0167,0.87995473,2,12,,5.00E-12,O15072,A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme),A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme),GO:0030574; GO:0030199; GO:0008201; GO:0004222; GO:0016485; GO:0005578; GO:0006508; GO:0008270,collagen catabolic process; collagen fibril organization; heparin binding; metalloendopeptidase activity; protein processing; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS3_HUMAN,Homo sapiens (Human),collagen biosynthetic process [GO:0032964]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular fibril organization [GO:0043206]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein processing [GO:0016485]; vascular endothelial growth factor production [GO:0010573] comp110778_c0_seq1,484,39.4628,1.02275686,16,25,,2.00E-21,O75106,Retina-specific copper amine oxidase (RAO) (EC 1.4.3.21) (Amine oxidase [copper-containing]) (Semicarbazide-sensitive amine oxidase) (SSAO),Retina-specific copper amine oxidase (RAO) (EC 1.4.3.21) (Amine oxidase [copper-containing]) (Semicarbazide-sensitive amine oxidase) (SSAO),GO:0052595; GO:0009308; GO:0052594; GO:0006584; GO:0005507; GO:0005737; GO:0009055; GO:0052596; GO:0005886; GO:0008131; GO:0048038; GO:0052593; GO:0007601,aliphatic-amine oxidase activity; amine metabolic process; aminoacetone:oxygen oxidoreductase(deaminating) activity; catecholamine metabolic process; copper ion binding; cytoplasm; electron carrier activity; phenethylamine:oxygen oxidoreductase (deaminating) activity; plasma membrane; primary amine oxidase activity; quinone binding; tryptamine:oxygen oxidoreductase (deaminating) activity; visual perception,PF01179;PF02727;PF02728;,,,,,,,,,AOC2_HUMAN,Homo sapiens (Human),amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; visual perception [GO:0007601]; xenobiotic metabolic process [GO:0006805] comp110789_c0_seq1,277,48.0144,0.32236042,23,23,,5.00E-13,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp110805_c1_seq1,1105,44.4344,0.29609823,2,9,,1.00E-15,Q9HCB6,Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor),Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor),GO:0007155; GO:0005615; GO:0005578,cell adhesion; extracellular space; proteinaceous extracellular matrix,PF02014;PF06468;PF00090;,,,,,,,,,SPON1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; protein O-linked fucosylation [GO:0036066] comp110805_c1_seq2,1130,45.5752,0.34311224,2,5,,5.00E-63,Q6P4U0,Thrombospondin type-1 domain-containing protein 7B,Thrombospondin type-1 domain-containing protein 7B,GO:0016021,integral to membrane,PF00090;,,,,,,,,,THS7B_MOUSE,Mus musculus (Mouse), comp110810_c0_seq1,1151,37.4457,0.78577775,74,85,,2.00E-119,P26990,ADP-ribosylation factor 6,ADP-ribosylation factor 6,GO:0005525; GO:0005794; GO:0006915; GO:0005938; GO:0030866; GO:0030139; GO:0005768; GO:0010008; GO:0090162; GO:0031527; GO:0001889; GO:0005886; GO:0030838; GO:0090004; GO:0034394; GO:0015031; GO:0035020; GO:0060998; GO:0051489; GO:0001726; GO:0031529; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; apoptotic process; cell cortex; cortical actin cytoskeleton organization; endocytic vesicle; endosome; endosome membrane; establishment of epithelial cell polarity; filopodium membrane; liver development; plasma membrane; positive regulation of actin filament polymerization; positive regulation of establishment of protein localization to plasma membrane; protein localization to cell surface; protein transport; regulation of Rac protein signal transduction; regulation of dendritic spine development; regulation of filopodium assembly; ruffle; ruffle organization; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,7.00E-127,CHOYP_ARF6.1.2,1.00E-20,ruditapes_c8663,,,,,ARF6_CHICK,Gallus gallus (Chicken),cortical actin cytoskeleton organization [GO:0030866]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; liver development [GO:0001889]; myeloid cell apoptotic process [GO:0033028]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of Rac protein signal transduction [GO:0035020]; ruffle organization [GO:0031529]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp110827_c0_seq1,509,49.9018,0.25607329,4,50,,3.00E-57,Q5RE98,Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B),Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B),GO:0016021; GO:0005741; GO:0016491,integral to membrane; mitochondrial outer membrane; oxidoreductase activity,PF01593;,,,,,,,,,AOFB_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp110834_c1_seq1,314,45.8599,0.42609128,1,29,,2.00E-30,Q66H65,NEDD4-binding protein 2-like 2 (Phosphonoformate immuno-associated protein 5 homolog),NEDD4-binding protein 2-like 2 (Phosphonoformate immuno-associated protein 5 homolog),,,,,,,,,,,,N42L2_RAT,Rattus norvegicus (Rat),blastocyst development [GO:0001824]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp110835_c0_seq1,355,44.507,0.82846402,0,32,,7.00E-20,P51658,Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),GO:0004303; GO:0001701; GO:0016021; GO:0001890; GO:0032526; GO:0006694; GO:0047035,estradiol 17-beta-dehydrogenase activity; in utero embryonic development; integral to membrane; placenta development; response to retinoic acid; steroid biosynthetic process; testosterone dehydrogenase (NAD+) activity,PF00106;,,,,,,,,,DHB2_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694] comp110839_c0_seq1,875,40.4571,1.06528557,15,1093,,1.00E-13,Q9NDE7,Insulin [Cleaved into: Insulin B chain; Insulin B chain'; Insulin A chain],Insulin [Cleaved into: Insulin B chain; Insulin B chain'; Insulin A chain],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF00049;,,,,,,,,,INS_APLCA,Aplysia californica (California sea hare),neuropeptide signaling pathway [GO:0007218] comp110845_c0_seq1,604,38.4106,0.09025161,18,79,,3.00E-11,Q80W31,Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74),Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN569_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp110861_c1_seq1,207,40.5797,1.18521285,0,0,,2.00E-08,Q68Y62,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0006635; GO:0016021; GO:0005741; GO:0006810,carnitine O-palmitoyltransferase activity; fatty acid beta-oxidation; integral to membrane; mitochondrial outer membrane; transport,PF00755;PF16484;,,,,,,,,,CPT1A_HORSE,Equus caballus (Horse),fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810] comp110890_c0_seq1,267,35.9551,0.23274317,6,9,,,,,,,,,,,1.00E-11,ruditapes_c17260,,,,,,, comp110892_c0_seq1,867,37.7163,0.3634569,870,171,,5.00E-19,Q9UL19,Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein),Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein),GO:0016021; GO:0016042; GO:0008285; GO:0004623; GO:0006644,integral to membrane; lipid catabolic process; negative regulation of cell proliferation; phospholipase A2 activity; phospholipid metabolic process,PF04970;,1.00E-15,CHOYP_BRAFLDRAFT_119296.11.16,8.00E-15,ruditapes_c11122,,,,,TIG3_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; negative regulation of cell proliferation [GO:0008285]; phospholipid metabolic process [GO:0006644] comp110893_c0_seq1,613,44.5351,1.036713,0,0,,,,,,,,,4.00E-32,CHOYP_CPIPJ_CPIJ012631.1.1,,,,,,,,, comp110893_c0_seq2,718,45.961,1.03975136,3,7,,4.00E-27,Q17QR6,Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13),Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT13_BOVIN,Bos taurus (Bovine),plasma membrane lactate transport [GO:0035879] comp110898_c3_seq1,251,67.7291,1.08186179,0,24,,2.00E-12,P23939,BamHI control element,BamHI control element,GO:0009307; GO:0006355; GO:0043565; GO:0006351,"DNA restriction-modification system; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF01381;,,,,,,,,,CEBA_BACAM,Bacillus amyloliquefaciens (Bacillus velezensis),"DNA restriction-modification system [GO:0009307]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp110906_c0_seq1,746,37.2654,0.42347015,32,64,,,,,,,,,,,3.00E-12,ruditapes_c9051,,,,,,, comp110914_c0_seq3,221,52.4887,0.79287338,0,20,,5.00E-08,P32004,Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171),Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171),GO:0007411; GO:0007596; GO:0007155; GO:0008219; GO:0007166; GO:0033631; GO:0009897; GO:0007157; GO:0007156; GO:0034109; GO:0016021; GO:0007159; GO:0050900; GO:0005886; GO:0050850; GO:0022409; GO:0042734; GO:0033691; GO:0043195,axon guidance; blood coagulation; cell adhesion; cell death; cell surface receptor signaling pathway; cell-cell adhesion mediated by integrin; external side of plasma membrane; heterophilic cell-cell adhesion; homophilic cell adhesion; homotypic cell-cell adhesion; integral to membrane; leukocyte cell-cell adhesion; leukocyte migration; plasma membrane; positive regulation of calcium-mediated signaling; positive regulation of cell-cell adhesion; presynaptic membrane; sialic acid binding; terminal bouton,PF13882;PF00041;PF07679;,,,,,,,,,L1CAM_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; cell adhesion [GO:0007155]; chemotaxis [GO:0006935]; leukocyte migration [GO:0050900]; nervous system development [GO:0007399]; positive regulation of axon extension [GO:0045773] comp110917_c0_seq1,550,44.7273,0.54644809,39,34,,5.00E-13,Q3TUF7,YEATS domain-containing protein 2,YEATS domain-containing protein 2,GO:0005671; GO:0043966; GO:0072686; GO:0000122; GO:0005634,Ada2/Gcn5/Ada3 transcription activator complex; histone H3 acetylation; mitotic spindle; negative regulation of transcription from RNA polymerase II promoter; nucleus,PF03366;,,,,,,,,,YETS2_MOUSE,Mus musculus (Mouse),"histone H3 acetylation [GO:0043966]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]" comp110919_c0_seq1,982,45.3157,0.80399216,25,49,,8.00E-16,Q9CWL2,Zinc finger protein castor homolog 1 (Castor-related protein),Zinc finger protein castor homolog 1 (Castor-related protein),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,5.00E-33,CHOYP_LOC100749506.1.1,,,,,,,CASZ1_MOUSE,Mus musculus (Mouse),"central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]" comp110921_c0_seq1,245,36.3265,0.2603218,3,5,,,,,,,,,,,1.00E-17,ruditapes_c15855,,,,,,, comp110930_c2_seq1,328,49.6951,0.74525006,11,6,,6.00E-34,Q96RK0,Protein capicua homolog,Protein capicua homolog,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00505;,8.00E-31,CHOYP_CIC.2.2,,,,,,,CIC_HUMAN,Homo sapiens (Human),"lung alveolus development [GO:0048286]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp110949_c0_seq1,598,45.1505,0.45442471,17,14,,8.00E-41,A8E0R9,Glutamate receptor-interacting protein 2 (xGRIP2) (xGRIP2.1),Glutamate receptor-interacting protein 2 (xGRIP2) (xGRIP2.1),GO:0005938; GO:0007281; GO:0008354; GO:0032019; GO:0007275; GO:0045495,cell cortex; germ cell development; germ cell migration; mitochondrial cloud; multicellular organismal development; pole plasm,PF00595;,,,,,,,,,GRIP2_XENLA,Xenopus laevis (African clawed frog),germ cell development [GO:0007281]; germ cell migration [GO:0008354]; multicellular organism development [GO:0007275] comp110955_c0_seq1,289,41.5225,0.64516901,6,27,,3.00E-14,Q9H790,Exonuclease V (Exo V) (hExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog),Exonuclease V (Exo V) (hExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog),GO:0051539; GO:0003677; GO:0005829; GO:0036297; GO:0046872; GO:0005634; GO:0042803; GO:0008310; GO:0045145,"4 iron, 4 sulfur cluster binding; DNA binding; cytosol; interstrand cross-link repair; metal ion binding; nucleus; protein homodimerization activity; single-stranded DNA 3'-5' exodeoxyribonuclease activity; single-stranded DNA 5'-3' exodeoxyribonuclease activity",PF09810;,,,,,,,,,EXO5_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297] comp110983_c0_seq1,557,62.6571,0.98714341,0,63,,5.00E-91,P25857,"Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic (EC 1.2.1.13) (NADP-dependent glyceraldehydephosphate dehydrogenase B)","Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic (EC 1.2.1.13) (NADP-dependent glyceraldehydephosphate dehydrogenase B)",GO:0051287; GO:0050661; GO:0048046; GO:0009941; GO:0031969; GO:0009570; GO:0009535; GO:0006006; GO:0004365; GO:0047100; GO:0019253; GO:0046686; GO:0009409; GO:0009416; GO:0009744; GO:0010319,NAD binding; NADP binding; apoplast; chloroplast envelope; chloroplast membrane; chloroplast stroma; chloroplast thylakoid membrane; glucose metabolic process; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity; reductive pentose-phosphate cycle; response to cadmium ion; response to cold; response to light stimulus; response to sucrose stimulus; stromule,PF02672;PF02800;PF00044;,,,,,,,,,G3PB_ARATH,Arabidopsis thaliana (Mouse-ear cress),glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to light stimulus [GO:0009416]; response to sucrose [GO:0009744] comp110984_c0_seq1,328,45.122,0.36374025,302,0,,5.00E-46,P18239,"ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) (Petite colonies protein 9)","ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) (Petite colonies protein 9)",GO:0005471; GO:0009060; GO:0009061; GO:0006915; GO:0015886; GO:0016021; GO:0005743; GO:0006839,ATP:ADP antiporter activity; aerobic respiration; anaerobic respiration; apoptotic process; heme transport; integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,2.00E-37,CHOYP_LOC100633390.5.5,5.00E-37,ruditapes_c408,,,,,ADT2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ADP transport [GO:0015866]; aerobic respiration [GO:0009060]; anaerobic respiration [GO:0009061]; apoptotic process [GO:0006915]; ATP transport [GO:0015867]; heme transport [GO:0015886]; mitochondrial transport [GO:0006839]; translation [GO:0006412]; transmembrane transport [GO:0055085] comp110988_c0_seq3,480,43.9583,0.69333634,7,5,,,,,,,,,,,5.00E-20,ruditapes2_c912,,,,,,, comp110993_c0_seq1,475,38.9474,0.77905419,16,49,,1.00E-14,Q54CK9,WAS protein family homolog DDB_G0292878,WAS protein family homolog DDB_G0292878,GO:0034314; GO:0071203; GO:0003779; GO:0045010; GO:0005769; GO:0006887; GO:0044655,Arp2/3 complex-mediated actin nucleation; WASH complex; actin binding; actin nucleation; early endosome; exocytosis; phagosome reneutralization,PF11945;,1.00E-11,CHOYP_LOC100376621.1.1,,,,,,,WASH1_DICDI,Dictyostelium discoideum (Slime mold),actin nucleation [GO:0045010]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; exocytosis [GO:0006887]; lysosomal transport [GO:0007041]; phagosome reneutralization [GO:0044655]; secretion of lysosomal enzymes [GO:0033299] comp110993_c1_seq1,630,51.746,0.38242521,22,46,,3.00E-46,Q5U4A3,WAS protein family homolog 1,WAS protein family homolog 1,GO:0034314; GO:0071203; GO:0043014; GO:0005769; GO:0031901; GO:0055037; GO:0055038; GO:0042147,"Arp2/3 complex-mediated actin nucleation; WASH complex; alpha-tubulin binding; early endosome; early endosome membrane; recycling endosome; recycling endosome membrane; retrograde transport, endosome to Golgi",PF11945;,,,,,,,,,WASH1_XENLA,Xenopus laevis (African clawed frog),"Arp2/3 complex-mediated actin nucleation [GO:0034314]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp110994_c0_seq1,704,42.1875,0.83538588,1,33,,4.00E-28,Q54K00,Aromatic amino acid aminotransferase DDB_G0287711 (EC 2.6.1.57),Aromatic amino acid aminotransferase DDB_G0287711 (EC 2.6.1.57),GO:0080130; GO:0008793; GO:0009058; GO:0005737; GO:0030170,L-phenylalanine:2-oxoglutarate aminotransferase activity; aromatic-amino-acid:2-oxoglutarate aminotransferase activity; biosynthetic process; cytoplasm; pyridoxal phosphate binding,PF00155;,,,,,,,,,AATR2_DICDI,Dictyostelium discoideum (Slime mold),biosynthetic process [GO:0009058] comp110994_c0_seq2,390,47.1795,0.98171377,0,0,,3.00E-06,Q7A875,HTH-type transcriptional regulator NorG,HTH-type transcriptional regulator NorG,GO:0003677; GO:0030170; GO:0003700; GO:0008483; GO:0006351,"DNA binding; pyridoxal phosphate binding; sequence-specific DNA binding transcription factor activity; transaminase activity; transcription, DNA-dependent",PF00155;PF00392;,,,,,,,,,NORG_STAAN,Staphylococcus aureus (strain N315),"transcription, DNA-templated [GO:0006351]" comp110995_c0_seq1,842,38.7173,0.48116506,42,0,,7.00E-53,Q9D1E5,Protein LMBR1L (Uteroglobin receptor),Protein LMBR1L (Uteroglobin receptor),GO:0006897; GO:0016021; GO:0005886,endocytosis; integral to membrane; plasma membrane,PF04791;,8.00E-36,CHOYP_LOC100376583.1.1,,,,,,,LMBRL_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897] comp110998_c0_seq1,792,48.6111,0.24146083,16,15,,1.00E-10,Q8BRH4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,,,,,,,,,MLL3_MOUSE,Mus musculus (Mouse),"eyelid development in camera-type eye [GO:0061029]; histone methylation [GO:0016571]; multicellular organism growth [GO:0035264]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; single fertilization [GO:0007338]; transcription, DNA-templated [GO:0006351]" comp111001_c0_seq1,928,45.1509,0.67763926,9,163,,6.00E-34,Q5XJ85,Myeloid differentiation primary response protein MyD88,Myeloid differentiation primary response protein MyD88,GO:0002755; GO:0002218; GO:0005737; GO:0006954; GO:0045087; GO:0043123; GO:0002237,MyD88-dependent toll-like receptor signaling pathway; activation of innate immune response; cytoplasm; inflammatory response; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; response to molecule of bacterial origin,PF00531;PF01582;,,,,,,,,,MYD88_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of innate immune response [GO:0002218]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237] comp111013_c0_seq1,281,53.7367,0.76299668,2,41,,4.00E-22,O42393,43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein),43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein),GO:0030054; GO:0005737; GO:0005856; GO:0045211; GO:0007268; GO:0008270,cell junction; cytoplasm; cytoskeleton; postsynaptic membrane; synaptic transmission; zinc ion binding,PF10579;PF13181;PF13639;,,,,,,,,,RAPSN_CHICK,Gallus gallus (Chicken),chemical synaptic transmission [GO:0007268] comp111015_c1_seq1,329,41.3374,1.21350894,0,27,,1.00E-11,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp111029_c0_seq1,408,43.6275,0.58695721,22,0,,9.00E-33,O60126,DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III),DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0006261; GO:0031422; GO:0043007; GO:0005739; GO:0000070; GO:0007000; GO:0005634; GO:0006301; GO:0000712; GO:0035861,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; DNA-dependent DNA replication; RecQ helicase-Topo III complex; maintenance of rDNA; mitochondrion; mitotic sister chromatid segregation; nucleolus organization; nucleus; postreplication repair; resolution of meiotic recombination intermediates; site of double-strand break,PF01131;PF01751;,,,,,,,,,TOP3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),DNA metabolic process [GO:0006259]; DNA topological change [GO:0006265]; maintenance of rDNA [GO:0043007]; mitotic DNA replication [GO:1902969]; mitotic sister chromatid segregation [GO:0000070]; postreplication repair [GO:0006301]; resolution of meiotic recombination intermediates [GO:0000712] comp111029_c1_seq1,604,41.0596,0.2891385,21,16,,1.00E-73,Q13472,DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha),DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0016605; GO:0005694; GO:0007126; GO:0008270,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; PML body; chromosome; meiosis; zinc ion binding,PF01131;PF01751;PF01396;PF06839;,7.00E-54,CHOYP_TOP3A.1.2,,,,,,,TOP3A_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA topological change [GO:0006265]; meiotic nuclear division [GO:0007126]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732] comp111037_c0_seq1,828,42.1498,0.59954065,22,12,,3.00E-38,Q91VN0,Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),GO:0044332; GO:0042813; GO:0060612; GO:0060033; GO:0009952; GO:1902262; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042074; GO:0060764; GO:0042632; GO:0008203; GO:0015026; GO:0048596; GO:0042733; GO:0060059; GO:0006897; GO:0005783; GO:0035426; GO:0001702; GO:0016021; GO:0005739; GO:0002076; GO:0005886; GO:0033690; GO:0051091; GO:0045944; GO:0043235; GO:0042981; GO:0046850; GO:0045598; GO:0061178; GO:0030278; GO:0061304; GO:0035019,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; adipose tissue development; anatomical structure regression; anterior/posterior pattern specification; apoptotic process involved in patterning of blood vessels; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cell migration involved in gastrulation; cell-cell signaling involved in mammary gland development; cholesterol homeostasis; cholesterol metabolic process; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; extracellular matrix-cell signaling; gastrulation with mouth forming second; integral to membrane; mitochondrion; osteoblast development; plasma membrane; positive regulation of osteoblast proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of apoptotic process; regulation of bone remodeling; regulation of fat cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of ossification; retinal blood vessel morphogenesis; somatic stem cell maintenance,PF00057;PF00058;,,,,,,,,,LRP5_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp111037_c2_seq1,293,40.273,0.68273654,4,3,,5.00E-08,O88322,Nidogen-2 (NID-2) (Entactin-2),Nidogen-2 (NID-2) (Entactin-2),GO:0005604; GO:0005509; GO:0009986; GO:0007160,basement membrane; calcium ion binding; cell surface; cell-matrix adhesion,PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID2_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198] comp111057_c0_seq1,451,42.5721,0.56661247,20,3,,,,,,,,,3.00E-31,CHOYP_VPS11.2.3,,,,,,,,, comp111057_c1_seq2,1406,42.2475,0.28900087,0,3,,8.00E-140,Q54YP4,Vacuolar protein sorting-associated protein 11 homolog,Vacuolar protein sorting-associated protein 11 homolog,GO:0030897; GO:0006886; GO:0042144; GO:0016192; GO:0008270,"HOPS complex; intracellular protein transport; vacuole fusion, non-autophagic; vesicle-mediated transport; zinc ion binding",PF00637;PF12451;,0,CHOYP_VPS11.3.3,,,,,,,VPS11_DICDI,Dictyostelium discoideum (Slime mold),"endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]" comp111057_c1_seq3,1514,42.4703,0.32390685,6,0,,0,Q91W86,Vacuolar protein sorting-associated protein 11 homolog,Vacuolar protein sorting-associated protein 11 homolog,GO:0005884; GO:0005769; GO:0030139; GO:0006886; GO:0031902; GO:0005765; GO:0000166; GO:0016192; GO:0008270,actin filament; early endosome; endocytic vesicle; intracellular protein transport; late endosome membrane; lysosomal membrane; nucleotide binding; vesicle-mediated transport; zinc ion binding,PF00637;PF12451;,,,,,,,,,VPS11_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of organelle assembly [GO:1902115]; regulation of protein stability [GO:0031647]; regulation of SNARE complex assembly [GO:0035542]; toxin transport [GO:1901998]; vesicle docking involved in exocytosis [GO:0006904] comp111066_c0_seq1,1134,37.8307,0.42103114,37,167,,4.00E-32,Q96KR6,Protein FAM210B,Protein FAM210B,GO:0016021,integral to membrane,PF06916;,,,1.00E-25,ruditapes2_c2729,,,,,F210B_HUMAN,Homo sapiens (Human), comp111072_c0_seq1,504,46.0317,0.19084045,15,26,,6.00E-23,Q7TPQ3,"E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)","E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)",GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0016874; GO:0000786; GO:0006334; GO:0005634; GO:0016567; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; ligase activity; nucleosome; nucleosome assembly; nucleus; protein ubiquitination; zinc ion binding,PF00271;PF00538;PF00176;,,,,,,,,,SHPRH_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] comp111073_c1_seq1,216,41.2037,0.22394701,4,12,,2.00E-19,Q9H3S7,Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14),Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14),GO:0005929; GO:0060271; GO:0016023; GO:0005769; GO:0005932; GO:0005634; GO:0035335; GO:0015031; GO:0004725; GO:0043162,cilium; cilium morphogenesis; cytoplasmic membrane-bounded vesicle; early endosome; microtubule basal body; nucleus; peptidyl-tyrosine dephosphorylation; protein transport; protein tyrosine phosphatase activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF13949;PF03097;PF00102;,2.00E-24,CHOYP_LOC100866004.1.1,,,,,,,PTN23_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp111084_c0_seq1,1441,46.0097,0.47498467,40,91,,4.00E-107,O95980,Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein),Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein),GO:0031225; GO:0001955; GO:0007566; GO:0030198; GO:0016020; GO:0008191; GO:0005886; GO:0004867,anchored to membrane; blood vessel maturation; embryo implantation; extracellular matrix organization; membrane; metalloendopeptidase inhibitor activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF07648;,4.00E-11,CHOYP_RECK.1.1,,,,,,,RECK_HUMAN,Homo sapiens (Human),blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684] comp111097_c0_seq1,619,38.4491,0.31286125,30,33,,2.00E-07,Q8BZI6,Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4),Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4),,,PF09778;,3.00E-21,CHOYP_GUCD1.1.1,,,,,,,CV013_MOUSE,Mus musculus (Mouse), comp111103_c2_seq1,208,41.8269,0.33140301,5,9,,3.00E-09,Q8VHY0,Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2),Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2),GO:0000187; GO:0001525; GO:0016324; GO:0008283; GO:0008347; GO:0016021; GO:0035556; GO:0031258; GO:0005886; GO:0050731; GO:0004871; GO:0048771; GO:0007169,activation of MAPK activity; angiogenesis; apical plasma membrane; cell proliferation; glial cell migration; integral to membrane; intracellular signal transduction; lamellipodium membrane; plasma membrane; positive regulation of peptidyl-tyrosine phosphorylation; signal transducer activity; tissue remodeling; transmembrane receptor protein tyrosine kinase signaling pathway,PF00054;PF02210;,,,,,,,,,CSPG4_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; cell proliferation [GO:0008283]; glial cell migration [GO:0008347]; intracellular signal transduction [GO:0035556]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; tissue remodeling [GO:0048771]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp111107_c0_seq1,729,40.3292,0.41024758,11,74,,3.00E-53,P35816,"[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)","[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)",GO:0004741; GO:0005509; GO:0016311; GO:0000287; GO:0005759; GO:0005739; GO:0006470; GO:0004722,[pyruvate dehydrogenase (lipoamide)] phosphatase activity; calcium ion binding; dephosphorylation; magnesium ion binding; mitochondrial matrix; mitochondrion; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,PDP1_BOVIN,Bos taurus (Bovine),dephosphorylation [GO:0016311] comp111112_c0_seq1,396,42.1717,0.51782939,0,54,,1.00E-09,P83740,Putative sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter),Putative sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter),GO:0016021; GO:0008523,integral to membrane; sodium-dependent multivitamin transmembrane transporter activity,PF00474;,,,,,,,,,SC5A6_DROME,Drosophila melanogaster (Fruit fly),sodium ion transport [GO:0006814] comp111143_c0_seq1,382,45.8115,0.65136501,12,36,,2.00E-14,Q4KM52,B-cell linker protein (Cytoplasmic adapter protein),B-cell linker protein (Cytoplasmic adapter protein),GO:0042113; GO:0005737; GO:0035556; GO:0005886,B cell activation; cytoplasm; intracellular signal transduction; plasma membrane,PF00017;,,,,,,,,,BLNK_RAT,Rattus norvegicus (Rat),B cell activation [GO:0042113]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556] comp111151_c1_seq1,488,38.3197,0.74508048,24,0,,1.00E-09,Q56R14,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_XENLA,Xenopus laevis (African clawed frog),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111152_c1_seq1,464,52.3707,0.78042321,0,59,,7.00E-18,Q7RTY7,Ovochymase-1 (EC 3.4.21.-),Ovochymase-1 (EC 3.4.21.-),GO:0005576; GO:0046872; GO:0006508; GO:0004252,extracellular region; metal ion binding; proteolysis; serine-type endopeptidase activity,PF00431;PF00089;,,,,,,,,,OVCH1_HUMAN,Homo sapiens (Human), comp111155_c0_seq2,258,43.7984,0.40596221,4,0,,,,,,,,,8.00E-23,CHOYP_SMARCA5.1.1,,,,,,,,, comp111155_c0_seq3,547,44.2413,0.39098304,7,0,,1.00E-63,Q7ZU90,Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),GO:0005524; GO:0016887; GO:0003677; GO:0006281; GO:0006338; GO:0004386; GO:0000166; GO:0005634; GO:0006974,ATP binding; ATPase activity; DNA binding; DNA repair; chromatin remodeling; helicase activity; nucleotide binding; nucleus; response to DNA damage stimulus,PF00271;PF16759;PF00176;,2.00E-66,CHOYP_CHD1L.1.1,,,,,,,CHD1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] comp111155_c0_seq4,548,44.5255,0.38244641,0,0,,2.00E-25,P87114,ATP-dependent helicase fft1 (EC 3.6.4.12) (Fun thirty-related protein 1),ATP-dependent helicase fft1 (EC 3.6.4.12) (Fun thirty-related protein 1),GO:0005524; GO:0004003; GO:0003677; GO:0006338; GO:0000790,ATP binding; ATP-dependent DNA helicase activity; DNA binding; chromatin remodeling; nuclear chromatin,PF00271;PF00176;,,,,,,,,,FFT1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338]; heterochromatin assembly involved in chromatin silencing [GO:0070869] comp111171_c0_seq1,280,31.4286,0.14635603,8,42,,1.00E-09,Q29RU9,Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),GO:0033514; GO:0050031; GO:0005777; GO:0008115; GO:0046653,L-lysine catabolic process to acetyl-CoA via L-pipecolate; L-pipecolate oxidase activity; peroxisome; sarcosine oxidase activity; tetrahydrofolate metabolic process,PF01266;,,,,,,,,,SOX_BOVIN,Bos taurus (Bovine),L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; tetrahydrofolate metabolic process [GO:0046653] comp111197_c1_seq1,394,39.5939,0.45514696,21,5,,3.00E-40,Q9Z1J2,Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2),Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2),GO:0005524; GO:0051301; GO:0046872; GO:0007067; GO:0005634; GO:0004674,ATP binding; cell division; metal ion binding; mitosis; nucleus; protein serine/threonine kinase activity,PF00069;,2.00E-45,CHOYP_BRAFLDRAFT_63676.1.1,,,,,,,NEK4_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]" comp111202_c0_seq1,470,42.1277,0.43468203,9,12,,1.00E-79,Q9UPR0,Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2),Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2),GO:0005509; GO:0005737; GO:0035556; GO:0006629; GO:0004435; GO:0005543; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid metabolic process; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF09279;PF16457;PF00388;PF00387;,3.00E-88,CHOYP_PLCL2.1.1,,,,,,,PLCL2_HUMAN,Homo sapiens (Human),"B-1a B cell differentiation [GO:0002337]; B cell proliferation involved in immune response [GO:0002322]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; positive regulation of receptor binding [GO:1900122]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of synaptic transmission, GABAergic [GO:0032228]" comp111202_c0_seq2,374,41.4439,0.43750313,2,0,,3.00E-06,Q54Y08,Probable Ras GTPase-activating-like protein ngap (DdNGAP),Probable Ras GTPase-activating-like protein ngap (DdNGAP),GO:0005099; GO:0005813; GO:0005737; GO:0031235; GO:0046580; GO:0007165,Ras GTPase activator activity; centrosome; cytoplasm; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; signal transduction,PF00168;PF00616;,,,,,,,,,NGAP_DICDI,Dictyostelium discoideum (Slime mold),negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165] comp111212_c0_seq1,257,51.3619,0.90527686,7,16,,,,,,,,,9.00E-35,CHOYP_LOC100647948.1.1,,,,,,,,, comp111213_c0_seq1,339,41.2979,0,8,0,,3.00E-25,Q8N201,Integrator complex subunit 1 (Int1),Integrator complex subunit 1 (Int1),GO:0034474; GO:0001833; GO:0016021; GO:0032039; GO:0043066; GO:0043154; GO:0031965; GO:0016180,U2 snRNA 3'-end processing; inner cell mass cell proliferation; integral to membrane; integrator complex; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nuclear membrane; snRNA processing,PF12432;,,,,,,,,,INT1_HUMAN,Homo sapiens (Human),snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp111217_c0_seq1,1019,40.9225,0.38476084,210,1466,,1.00E-132,Q9H1D9,DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39),DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39),GO:0003677; GO:0005666; GO:0003899; GO:0005829; GO:0051607; GO:0045087; GO:0045089; GO:0032728; GO:0006359; GO:0006386; GO:0006385,DNA binding; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; cytosol; defense response to virus; innate immune response; positive regulation of innate immune response; positive regulation of interferon-beta production; regulation of transcription from RNA polymerase III promoter; termination of RNA polymerase III transcription; transcription elongation from RNA polymerase III promoter,PF05158;,1.00E-117,CHOYP_RPC6.1.2,,,,,,,RPC6_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383] comp111219_c1_seq1,384,41.1458,0.49383051,14,25,,2.00E-27,Q8SQC1,Scavenger receptor class B member 1 (SRB1) (High density lipoprotein receptor SR-BI) (SR-BI),Scavenger receptor class B member 1 (SRB1) (High density lipoprotein receptor SR-BI) (SR-BI),GO:0005901; GO:0007155; GO:0016021,caveola; cell adhesion; integral to membrane,PF01130;,,,,,,,,,SCRB1_PIG,Sus scrofa (Pig),transcytosis [GO:0045056] comp111230_c1_seq1,887,41.2627,0.67879615,23,22,,6.00E-24,Q5R6Y9,Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1),Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1),GO:0003677; GO:0072487; GO:0043984; GO:0035064; GO:0006355; GO:0006351,"DNA binding; MSL complex; histone H4-K16 acetylation; methylated histone residue binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05712;PF11717;,5.00E-13,CHOYP_MSL3.1.1,3.00E-13,ruditapes_c6995,,,,,MS3L1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"histone H4-K16 acetylation [GO:0043984]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111240_c0_seq1,545,43.6697,0.74440549,9,19,,3.00E-38,Q9NB71,E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1),E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1),GO:0030509; GO:0007628; GO:0006914; GO:0016023; GO:0040011; GO:0030514; GO:0045886; GO:0005634; GO:0005886; GO:0050808; GO:0006351; GO:0004842; GO:0008270,"BMP signaling pathway; adult walking behavior; autophagy; cytoplasmic membrane-bounded vesicle; locomotion; negative regulation of BMP signaling pathway; negative regulation of synaptic growth at neuromuscular junction; nucleus; plasma membrane; synapse organization; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF08005;PF00415;,,,,,,,,,HIW_DROME,Drosophila melanogaster (Fruit fly),"adult walking behavior [GO:0007628]; autophagy [GO:0006914]; BMP signaling pathway [GO:0030509]; locomotion [GO:0040011]; long-term memory [GO:0007616]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; response to axon injury [GO:0048678]; synapse organization [GO:0050808]; transcription, DNA-templated [GO:0006351]" comp111240_c1_seq1,272,45.2206,1.01059007,1,1,,4.00E-07,Q8CAS9,Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog),Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog),GO:0003950; GO:0005737; GO:0005829; GO:0006302; GO:0005634; GO:0060330,NAD+ ADP-ribosyltransferase activity; cytoplasm; cytosol; double-strand break repair; nucleus; regulation of response to interferon-gamma,PF01661;,,,,,,,,,PARP9_MOUSE,Mus musculus (Mouse),double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330] comp111242_c0_seq1,604,40.5629,0.60379407,28,5,,,,,,,,,1.00E-49,CHOYP_LOC100369444.1.1,,,,,,,,, comp111246_c0_seq1,2040,43.5294,0.51772871,95,79,,5.00E-125,O60879,Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2),Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2),GO:0005794; GO:0030041; GO:0030154; GO:0000910; GO:0005829; GO:0005769; GO:0007292; GO:0005739; GO:0007275; GO:0005730; GO:0048477; GO:0005102,Golgi apparatus; actin filament polymerization; cell differentiation; cytokinesis; cytosol; early endosome; female gamete generation; mitochondrion; multicellular organismal development; nucleolus; oogenesis; receptor binding,PF06345;PF06367;PF06371;PF02181;,1.00E-50,CHOYP_DIAP2.1.1,,,,,,,DIAP2_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; cytokinesis [GO:0000910]; female gamete generation [GO:0007292]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477] comp111254_c0_seq1,485,41.4433,0.44505684,15,12,,7.00E-29,P59764,Dedicator of cytokinesis protein 4,Dedicator of cytokinesis protein 4,GO:0030675; GO:0060326; GO:0005829; GO:0012505; GO:0005085; GO:0016020; GO:0007264; GO:0032420,Rac GTPase activator activity; cell chemotaxis; cytosol; endomembrane system; guanyl-nucleotide exchange factor activity; membrane; small GTPase mediated signal transduction; stereocilium,PF06920;PF14429;PF16172;PF07653;,,,,,,,,,DOCK4_MOUSE,Mus musculus (Mouse),cell chemotaxis [GO:0060326]; negative regulation of vascular smooth muscle contraction [GO:1904694]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; small GTPase mediated signal transduction [GO:0007264] comp111254_c1_seq1,472,44.2797,0.22810673,13,60,,1.00E-51,Q8BUR4,Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),GO:0006915; GO:0016477; GO:0005737; GO:0005085; GO:0016020; GO:0006909; GO:0007264,apoptotic process; cell migration; cytoplasm; guanyl-nucleotide exchange factor activity; membrane; phagocytosis; small GTPase mediated signal transduction,PF06920;PF14429;PF16172;PF14604;,6.00E-47,CHOYP_DOCK1.2.2,,,,,,,DOCK1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; hematopoietic progenitor cell differentiation [GO:0002244]; phagocytosis [GO:0006909]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; small GTPase mediated signal transduction [GO:0007264] comp111265_c0_seq1,1430,29.3007,0.58835113,1320,57,,8.00E-24,Q3KNL4,UPF0728 protein C10orf53 homolog,UPF0728 protein C10orf53 homolog,,,PF15092;,,,1.00E-53,ruditapes_c12093,,,,,CJ053_MOUSE,Mus musculus (Mouse), comp111280_c0_seq1,1010,44.2574,0.53161076,25,78,,3.00E-84,Q96JM7,Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1),Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1),GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02820;PF00536;,6.00E-32,CHOYP_LMBL3.1.1,,,,,,,LMBL3_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111297_c1_seq1,771,42.153,0.71190468,15,55,,8.00E-37,O74227,Guanine nucleotide-binding protein subunit alpha,Guanine nucleotide-binding protein subunit alpha,GO:0005525; GO:0003924; GO:0007189; GO:0046872; GO:0004871,GTP binding; GTPase activity; adenylate cyclase-activating G-protein coupled receptor signaling pathway; metal ion binding; signal transducer activity,PF00503;,,,,,,,,,GPA1_COCHE,Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis),G-protein coupled receptor signaling pathway [GO:0007186] comp111297_c2_seq2,1008,39.5833,0.89586592,31,64,,1.00E-122,P30684,Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein),Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein),GO:0007186; GO:0005525; GO:0003924; GO:0046872; GO:0004871,G-protein coupled receptor signaling pathway; GTP binding; GTPase activity; metal ion binding; signal transducer activity,PF00503;,3.00E-130,CHOYP_GNAS.3.3,,,,,,,GNAS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),G-protein coupled receptor signaling pathway [GO:0007186] comp111310_c0_seq2,718,39.8329,0.80968626,7,41,,2.00E-13,Q9GPR3,TM2 domain-containing protein DDB_G0277895,TM2 domain-containing protein DDB_G0277895,GO:0016021,integral to membrane,PF05154;,,,,,,,,,TM2D1_DICDI,Dictyostelium discoideum (Slime mold), comp111319_c0_seq1,316,31.0127,0.52833862,20,6,,,,,,,,,2.00E-12,CHOYP_contig_002283,,,,,,,,, comp111340_c1_seq1,718,39.9721,0.3851293,28,63,,2.00E-21,Q5E960,Zinc transporter ZIP3 (Solute carrier family 39 member 3) (Zrt- and Irt-like protein 3) (ZIP-3),Zinc transporter ZIP3 (Solute carrier family 39 member 3) (Zrt- and Irt-like protein 3) (ZIP-3),GO:0016021; GO:0005385,integral to membrane; zinc ion transmembrane transporter activity,PF02535;,,,,,,,,,S39A3_BOVIN,Bos taurus (Bovine),cell morphogenesis [GO:0000902]; embryonic cranial skeleton morphogenesis [GO:0048701]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; T cell homeostasis [GO:0043029]; zinc II ion transmembrane transport [GO:0071577] comp111340_c2_seq1,378,31.746,0.32019374,18,37,,2.00E-12,Q3SYU3,Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zrt- and Irt-like protein 1) (ZIP-1),Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zrt- and Irt-like protein 1) (ZIP-1),GO:0016021; GO:0005886; GO:0071577; GO:0005385,integral to membrane; plasma membrane; zinc ion transmembrane transport; zinc ion transmembrane transporter activity,PF02535;,,,,,,,,,S39A1_BOVIN,Bos taurus (Bovine),embryonic cranial skeleton morphogenesis [GO:0048701]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; zinc II ion transmembrane transport [GO:0071577] comp111341_c0_seq1,355,43.662,0.44949852,1,1,,5.00E-07,Q9CS74,Protein SGT1 homolog (Ecdysoneless homolog),Protein ecdysoneless homolog,GO:0008283; GO:0005737; GO:0005634; GO:2000045; GO:0006355; GO:0006351,"cell proliferation; cytoplasm; nucleus; regulation of G1/S transition of mitotic cell cycle; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07093;,,,,,,,,,SGT1_MOUSE,Mus musculus (Mouse),cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp111341_c1_seq1,374,41.9786,0.57300919,13,19,,7.00E-10,O95905,Protein SGT1 (hSGT1) (Protein ecdysoneless homolog) (Suppressor of GCR2),Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1),GO:0008283; GO:0005737; GO:0005634; GO:2000045; GO:0006110; GO:0006355; GO:0003713; GO:0006366,"cell proliferation; cytoplasm; nucleus; regulation of G1/S transition of mitotic cell cycle; regulation of glycolysis; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter",PF07093;,,,,,,,,,SGT1_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of glycolytic process [GO:0006110]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp111346_c0_seq1,359,40.9471,0.86957196,11,3,,,,,,,,,7.00E-19,CHOYP_LOC100215960.1.1,,,,,,,,, comp111357_c0_seq1,392,46.1735,0.72154692,9,22,,5.00E-17,P70563,Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Protein GFG),Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Protein GFG),GO:0016787; GO:0005739; GO:0005634,hydrolase activity; mitochondrion; nucleus,PF00293;,,,,,,,,,NUDT6_RAT,Rattus norvegicus (Rat), comp111358_c0_seq1,1700,42.5882,0.40990196,98,96,,1.00E-92,Q80Y56,Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20),Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20),GO:0031901; GO:0046872; GO:0005886; GO:0015031,early endosome membrane; metal ion binding; plasma membrane; protein transport,PF01363;PF11464;,5.00E-29,CHOYP_BRAFLDRAFT_215186.1.1,,,,,,,RBNS5_MOUSE,Mus musculus (Mouse),early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; Golgi to endosome transport [GO:0006895]; Golgi to lysosome transport [GO:0090160]; Golgi to vacuole transport [GO:0006896]; protein transport [GO:0015031]; regulation of Golgi organization [GO:1903358]; vacuole inheritance [GO:0000011] comp111362_c0_seq2,211,45.0237,0.38828711,1,0,,5.00E-14,Q5IZC5,Cryptochrome-1,Cryptochrome-1,GO:0003677; GO:0003913; GO:0006281; GO:0000166; GO:0005634; GO:0009881; GO:0018298; GO:0006355; GO:0048511; GO:0006351,"DNA binding; DNA photolyase activity; DNA repair; nucleotide binding; nucleus; photoreceptor activity; protein-chromophore linkage; regulation of transcription, DNA-dependent; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY1_ERIRU,Erithacus rubecula (European robin),"protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp111369_c1_seq1,343,47.5219,0.56971276,3,13,,9.00E-29,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp111376_c0_seq1,377,42.9708,0.23101767,3,20,,3.00E-16,Q80T22,Sodium-dependent glucose transporter 1 (rNaGLT1),Sodium-dependent glucose transporter 1 (rNaGLT1) (Major facilitator superfamily domain-containing protein 4B),GO:0016324; GO:0005355; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; glucose transmembrane transporter activity; integral to membrane; sodium ion transport; symporter activity,PF07690;,1.00E-16,CHOYP_BRAFLDRAFT_85464.2.2,,,,,,,NAGT1_RAT,Rattus norvegicus (Rat),sodium ion transport [GO:0006814] comp111387_c0_seq1,379,50.3958,0.60869989,7,6,,1.00E-61,P97608,5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase),5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase),GO:0017168; GO:0005524; GO:0008152,5-oxoprolinase (ATP-hydrolyzing) activity; ATP binding; metabolic process,PF05378;PF01968;PF02538;,4.00E-60,CHOYP_BRAFLDRAFT_214348.1.2,,,,,,,OPLA_RAT,Rattus norvegicus (Rat), comp111403_c0_seq2,385,28.3117,0.78138179,0,2,,,,,,,,,,,2.00E-25,ruditapes_c9835,,,,,,, comp111427_c2_seq1,751,44.0746,0.60747703,20,45,,3.00E-95,Q5R4A5,Sorting nexin-17,Sorting nexin-17,GO:0016023; GO:0030659; GO:0005829; GO:0005769; GO:0035091; GO:0015031; GO:0007165,cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle membrane; cytosol; early endosome; phosphatidylinositol binding; protein transport; signal transduction,PF00787;,3.00E-59,CHOYP_BRAFLDRAFT_240864.1.1,2.00E-22,ruditapes_c30239,,,,,SNX17_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031]; signal transduction [GO:0007165] comp111439_c0_seq2,206,28.6408,3.09317634,0,19,,,,,,,,,1.00E-12,CHOYP_contig_011005,,,,,,,,, comp111442_c0_seq1,961,28.1998,1.13151237,30,63,,3.00E-17,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp111458_c0_seq2,1422,40.7173,0.57964758,0,0,,5.00E-137,Q6NYY9,Vacuole membrane protein 1 (Transmembrane protein 49),Vacuole membrane protein 1 (Transmembrane protein 49),GO:0005783; GO:0033116; GO:0016021; GO:0005886; GO:0005774,endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; plasma membrane; vacuolar membrane,,5.00E-47,CHOYP_VMP1.1.1,,,,,,,VMP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),endoplasmic reticulum organization [GO:0007029]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; regulation of autophagy [GO:0010506] comp111458_c0_seq5,1359,40.8389,0.54993247,0,0,,2.00E-147,Q6NYY9,Vacuole membrane protein 1 (Transmembrane protein 49),Vacuole membrane protein 1 (Transmembrane protein 49),GO:0005783; GO:0033116; GO:0016021; GO:0005886; GO:0005774,endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; plasma membrane; vacuolar membrane,,3.00E-113,CHOYP_VMP1.1.1,,,,,,,VMP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),endoplasmic reticulum organization [GO:0007029]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; regulation of autophagy [GO:0010506] comp111459_c0_seq1,415,46.2651,0.32187652,12,14,,1.00E-12,Q5VV63,Attractin-like protein 1,Attractin-like protein 1,GO:0007186; GO:0030246; GO:0016021; GO:0007275; GO:0004872,G-protein coupled receptor signaling pathway; carbohydrate binding; integral to membrane; multicellular organismal development; receptor activity,PF00431;PF07974;PF01344;PF00059;PF01437;,,,,,,,,,ATRN1_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186] comp111461_c0_seq1,692,44.0751,0.39600083,31,37,,8.00E-101,Q4V9Y0,Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog),Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog),GO:0005794; GO:0006869; GO:0015031,Golgi apparatus; lipid transport; protein transport,,2.00E-80,CHOYP_VPS51.1.1,,,,,,,VPS51_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),endocytic recycling [GO:0032456]; lipid transport [GO:0006869]; protein transport [GO:0015031] comp111481_c0_seq1,1006,39.165,0.67479448,84,23,,9.00E-11,Q9D5R3,Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41),Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41),GO:0005814; GO:0042384; GO:0048278,centriole; cilium assembly; vesicle docking,,,,,,,,,,CCD41_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; establishment of centrosome localization [GO:0051660]; protein localization to centrosome [GO:0071539]; vesicle docking [GO:0048278] comp111492_c0_seq1,486,41.7695,0.61995954,1,75,,1.00E-17,P20241,Neuroglian,Neuroglian,GO:0008366; GO:0048675; GO:0005509; GO:0061343; GO:0048036; GO:0048813; GO:0007173; GO:0060857; GO:0008050; GO:0030175; GO:0007560; GO:0016021; GO:0016328; GO:0008049; GO:0035011; GO:0016319; GO:0021682; GO:0007158; GO:0005919; GO:0045924; GO:0035151; GO:0019991; GO:0050808; GO:0005923,"axon ensheathment; axon extension; calcium ion binding; cell adhesion involved in heart morphogenesis; central complex development; dendrite morphogenesis; epidermal growth factor receptor signaling pathway; establishment of glial blood-brain barrier; female courtship behavior; filopodium; imaginal disc morphogenesis; integral to membrane; lateral plasma membrane; male courtship behavior; melanotic encapsulation of foreign target; mushroom body development; nerve maturation; neuron cell-cell adhesion; pleated septate junction; regulation of female receptivity; regulation of tube size, open tracheal system; septate junction assembly; synapse organization; tight junction",PF13882;PF00041;PF07679;PF00047;,,,,,,,,,NRG_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" comp111494_c2_seq1,345,43.4783,0.8172307,1,55,,1.00E-06,Q2KIB3,Transmembrane protein 101,Transmembrane protein 101,GO:0016021; GO:0043123; GO:0004871,integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity,PF15111;,,,,,,,,,TM101_BOVIN,Bos taurus (Bovine),positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp111498_c0_seq1,798,43.3584,0.44131525,16,118,,3.00E-42,Q99KR6,E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (Phafin-1) (RING finger protein 34) (RING finger protein RIFF),E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (Phafin-1) (RING finger protein 34),GO:0006915; GO:0012505; GO:0016020; GO:0016607; GO:0004842; GO:0008270,apoptotic process; endomembrane system; membrane; nuclear speck; ubiquitin-protein ligase activity; zinc ion binding,,6.00E-18,CHOYP_RFFL.1.1,,,,,,,RNF34_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of oxygen metabolic process [GO:2000374]" comp111500_c0_seq1,260,35.7692,1.10179866,1,0,,3.00E-10,Q9N294,"Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) (Fragment)","Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) (Fragment)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT5_PANPA,Pan paniscus (Pygmy chimpanzee) (Bonobo),protein glycosylation [GO:0006486] comp111500_c1_seq1,203,39.9015,1.53195207,4,0,,3.00E-11,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp111503_c0_seq3,463,33.2613,0.07825977,18,24,,3.00E-07,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111512_c2_seq1,407,45.9459,0.46703579,13,9,,3.00E-43,Q28D01,WD repeat-containing protein 26,WD repeat-containing protein 26,GO:0005737,cytoplasm,PF00400;,1.00E-42,CHOYP_WDR26.1.1,,,,,,,WDR26_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp111546_c0_seq1,496,41.5323,0.56649166,15,31,,1.00E-19,A8C754,Thyroid adenoma-associated protein homolog,Thyroid adenoma-associated protein homolog,,,PF10350;,,,,,,,,,THADA_CHICK,Gallus gallus (Chicken), comp111552_c0_seq1,1506,40.9031,0.493342,7,31,,6.00E-143,Q24K02,Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin),Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin),GO:0005524; GO:0050435; GO:0010815; GO:0009986; GO:0005829; GO:0008340; GO:0005615; GO:0043559; GO:1901143; GO:0004222; GO:0005739; GO:0005634; GO:0005777; GO:0005886; GO:0032461; GO:0051260; GO:0051603; GO:0010992; GO:0008270,ATP binding; beta-amyloid metabolic process; bradykinin catabolic process; cell surface; cytosol; determination of adult lifespan; extracellular space; insulin binding; insulin catabolic process; metalloendopeptidase activity; mitochondrion; nucleus; peroxisome; plasma membrane; positive regulation of protein oligomerization; protein homooligomerization; proteolysis involved in cellular protein catabolic process; ubiquitin homeostasis; zinc ion binding,PF00675;PF05193;PF16187;,,,,,,,,,IDE_BOVIN,Bos taurus (Bovine),beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; insulin catabolic process [GO:1901143]; peptide catabolic process [GO:0043171]; positive regulation of protein oligomerization [GO:0032461]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992] comp111552_c0_seq2,1290,40.6202,0.50806059,3,0,,,,,,,,,1.00E-55,CHOYP_IDE.1.3,6.00E-75,ruditapes_c10964,,,,,,, comp111555_c1_seq1,398,40.201,0.25725501,10,32,,1.00E-12,Q8NFU3,Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1,Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1,GO:0005737; GO:0005739; GO:0048471,cytoplasm; mitochondrion; perinuclear region of cytoplasm,PF00581;,,,,,,,,,TSTD1_HUMAN,Homo sapiens (Human), comp111565_c2_seq1,378,37.5661,0.45847095,6,34,,2.00E-43,Q5RDC9,UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Solute carrier family 35 member D2),UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Solute carrier family 35 member D2),GO:0000139; GO:0008643; GO:0016021,Golgi membrane; carbohydrate transport; integral to membrane,PF03151;,7.00E-26,CHOYP_NEMVEDRAFT_V1G162565.1.1,,,,,,,S35D2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),carbohydrate transport [GO:0008643]; chondroitin sulfate biosynthetic process [GO:0030206]; embryonic skeletal system development [GO:0048706] comp111572_c1_seq1,302,49.3377,0.44250211,1,0,,2.00E-27,Q925T6,Glutamate receptor-interacting protein 1 (GRIP-1),Glutamate receptor-interacting protein 1 (GRIP-1),GO:0030054; GO:0016023; GO:0030425; GO:0005783; GO:0045121; GO:0005886; GO:0045211; GO:0008104; GO:0055037,cell junction; cytoplasmic membrane-bounded vesicle; dendrite; endoplasmic reticulum; membrane raft; plasma membrane; postsynaptic membrane; protein localization; recycling endosome,PF00595;,,,,,,,,,GRIP1_MOUSE,Mus musculus (Mouse),dendrite development [GO:0016358]; protein localization [GO:0008104] comp111579_c0_seq1,527,41.556,0.37420404,13,47,,7.00E-08,Q6DFC0,Solute carrier family 41 member 2,Solute carrier family 41 member 2,GO:0008324; GO:0016021; GO:0005886,cation transmembrane transporter activity; integral to membrane; plasma membrane,PF01769;,,,,,,,,,S41A2_XENLA,Xenopus laevis (African clawed frog), comp111592_c0_seq1,665,33.5338,0.59271979,23,146,,2.00E-11,Q96K62,Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499),Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT45_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111594_c0_seq1,638,39.0282,0.70174591,6,69,,4.00E-15,Q9UDY8,Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase),Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase),GO:0001923; GO:0032449; GO:0038095; GO:0042098; GO:0050852; GO:0007250; GO:0004197; GO:0005829; GO:0045087; GO:0043066; GO:0051168; GO:0005634; GO:0048471; GO:0005886; GO:0043123; GO:0051092; GO:0050870; GO:0002726; GO:0032743; GO:0031398; GO:0051259; GO:0006508; GO:0050856; GO:0009620; GO:0002237; GO:0004871; GO:0004842,B-1 B cell differentiation; CBM complex; Fc-epsilon receptor signaling pathway; T cell proliferation; T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; cysteine-type endopeptidase activity; cytosol; innate immune response; negative regulation of apoptotic process; nuclear export; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; positive regulation of T cell cytokine production; positive regulation of interleukin-2 production; positive regulation of protein ubiquitination; protein oligomerization; proteolysis; regulation of T cell receptor signaling pathway; response to fungus; response to molecule of bacterial origin; signal transducer activity; ubiquitin-protein ligase activity,PF13895;,,,,,,,,,MALT1_HUMAN,Homo sapiens (Human),activation of NF-kappaB-inducing kinase activity [GO:0007250]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; protein oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; response to molecule of bacterial origin [GO:0002237]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] comp111599_c0_seq1,540,45.5556,0.25072914,4,2,,4.00E-30,A1L0Z4,TBCC domain-containing protein 1,TBCC domain-containing protein 1,GO:0000902; GO:0005737; GO:0007010; GO:0005815; GO:0000922,cell morphogenesis; cytoplasm; cytoskeleton organization; microtubule organizing center; spindle pole,PF07986;,,,,,,,,,TBCC1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010] comp111606_c1_seq1,680,39.8529,0.44832223,44,57,,4.00E-19,Q568K2,Protein phosphatase 1 regulatory subunit 11,Protein phosphatase 1 regulatory subunit 11,GO:0004864,protein phosphatase inhibitor activity,PF07491;,5.00E-24,CHOYP_COX1.12.15,,,,,,,PP1RB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of phosphoprotein phosphatase activity [GO:0032515] comp111618_c0_seq1,273,35.1648,0.71386108,28,58,,,,,,,,,,,2.00E-16,ruditapes_c27792,,,,,,, comp111619_c0_seq2,392,40.3061,0.25449413,0,0,,2.00E-07,Q8NBI5,Solute carrier family 43 member 3 (Protein FOAP-13),Solute carrier family 43 member 3 (Protein FOAP-13),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S43A3_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp111619_c1_seq1,278,45.6835,0.41538999,11,15,,2.00E-10,A4IHK6,Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2),Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2),GO:0015179; GO:0016021,L-amino acid transmembrane transporter activity; integral to membrane,PF07690;,,,,,,,,,LAT4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp111630_c0_seq1,250,40.4,0.19842215,5,11,,,,,,,,,1.00E-33,CHOYP_LOC592709.1.1,,,,,,,,, comp111632_c2_seq1,315,45.7143,0.45514862,23,0,,,,,,,,,6.00E-13,CHOYP_TRIADDRAFT_56963.1.1,,,,,,,,, comp111633_c0_seq1,878,43.6219,1.12661722,3,87,,4.00E-18,Q8I034,Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein) (Cauxin),Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein) (Cauxin),GO:0004091; GO:0005576,carboxylesterase activity; extracellular region,PF00135;,,,,,,,,,EST5A_FELCA,Felis catus (Cat) (Felis silvestris catus), comp111633_c0_seq2,707,45.686,0.84214734,4,24,,6.00E-16,Q6NT32,Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin),Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin),GO:0004091; GO:0005576,carboxylesterase activity; extracellular region,PF00135;,,,,,,,,,EST5A_HUMAN,Homo sapiens (Human), comp111636_c0_seq1,349,41.5473,0.47610185,5,8,,6.00E-10,Q6DE37,Glucoside xylosyltransferase 2 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 4),Glucoside xylosyltransferase 2 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 4),GO:0016266; GO:0035252; GO:0016021,O-glycan processing; UDP-xylosyltransferase activity; integral to membrane,PF01501;,,,,,,,,,GXLT2_XENLA,Xenopus laevis (African clawed frog),O-glycan processing [GO:0016266] comp111657_c0_seq1,498,35.3414,0.19992068,5,14,,5.00E-24,Q7TSG2,RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase),RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase),GO:0008420; GO:0015629; GO:0051301; GO:0005813; GO:0005737; GO:0010458; GO:0030496; GO:0005634; GO:0006470; GO:0051233; GO:0000922,CTD phosphatase activity; actin cytoskeleton; cell division; centrosome; cytoplasm; exit from mitosis; midbody; nucleus; protein dephosphorylation; spindle midzone; spindle pole,PF09309;PF03031;,,,,,,,,,CTDP1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; exit from mitosis [GO:0010458]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; protein dephosphorylation [GO:0006470] comp111661_c0_seq1,554,41.3357,0.33898416,10,98,,5.00E-76,O14972,Down syndrome critical region protein 3 (Down syndrome critical region protein A),Down syndrome critical region protein 3 (Down syndrome critical region protein A),GO:0005634; GO:0030904; GO:0007034,nucleus; retromer complex; vacuolar transport,PF03643;,1.00E-38,CHOYP_LOC100640206.1.1,2.00E-103,ruditapes_c16788,,,,,DSCR3_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886] comp111675_c0_seq1,665,39.5489,0.69351077,311,965,,,,,,,,,6.00E-17,CHOYP_ACLY.1.1,5.00E-28,ruditapes2_c2095,,,,,,, comp111678_c1_seq1,390,40.2564,0.3188214,17,36,,4.00E-21,E9QBI7,"Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)","Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)",GO:0002024; GO:0097009; GO:0006006; GO:0016021; GO:0006629; GO:0046872; GO:0004222; GO:0006515; GO:0005743; GO:0031966; GO:0010637; GO:0006950,diet induced thermogenesis; energy homeostasis; glucose metabolic process; integral to membrane; lipid metabolic process; metal ion binding; metalloendopeptidase activity; misfolded or incompletely synthesized protein catabolic process; mitochondrial inner membrane; mitochondrial membrane; negative regulation of mitochondrial fusion; response to stress,PF01435;,,,,,,,,,OMA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrial protein processing [GO:0034982]; negative regulation of mitochondrial fusion [GO:0010637]; response to stress [GO:0006950] comp111683_c0_seq1,428,44.6262,0.80072901,23,34,,3.00E-35,B4DU55,Zinc finger protein 879,Zinc finger protein 879,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN879_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111695_c0_seq1,282,45.7447,0.47643697,0,11,,4.00E-08,Q9UN70,Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43),Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43),GO:0005509; GO:0016339; GO:0007156; GO:0016021; GO:0016020; GO:0005886,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to membrane; membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDGK_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse organization [GO:0050808] comp111695_c1_seq1,304,45.0658,0.39253964,1,17,,2.00E-08,Q767I8,Protocadherin alpha-4 (PCDH-alpha-4) (Cadherin-related neuronal receptor 4),Protocadherin alpha-4 (PCDH-alpha-4) (Cadherin-related neuronal receptor 4),GO:0005509; GO:0007156; GO:0016021; GO:0042476; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; odontogenesis; plasma membrane,PF00028;PF08266;PF15974;,,,,,,,,,PCDA4_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; odontogenesis [GO:0042476] comp111703_c0_seq1,710,40.5634,0.81116232,9,89,,2.00E-10,Q57951,Universal stress protein MJ0531 (USP MJ0531),Universal stress protein MJ0531 (USP MJ0531),GO:0006950,response to stress,PF00582;,2.00E-11,CHOYP_LOC100180855.3.4,,,,,,,Y531_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),response to stress [GO:0006950] comp111704_c1_seq1,814,44.4717,0.53342764,43,16,,3.00E-59,Q96CU9,FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-),FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-),GO:0016021; GO:0005739; GO:0016491,integral to membrane; mitochondrion; oxidoreductase activity,PF01266;,5.00E-19,CHOYP_CPIPJ_CPIJ004840.1.1,,,,,,,FXRD1_HUMAN,Homo sapiens (Human),mitochondrial respiratory chain complex I assembly [GO:0032981] comp111706_c0_seq1,434,40.0922,0.80630641,20,12,,6.00E-09,Q9ULP9,TBC1 domain family member 24,TBC1 domain family member 24,GO:0005097; GO:0005737; GO:0031175; GO:0032851,Rab GTPase activator activity; cytoplasm; neuron projection development; positive regulation of Rab GTPase activity,PF00566;PF07534;,,,,,,,,,TBC24_HUMAN,Homo sapiens (Human),neuron projection development [GO:0031175] comp111723_c0_seq1,778,43.7018,0.48561119,6,4,,2.00E-55,Q14185,Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),GO:0038096; GO:0005096; GO:0006915; GO:0007411; GO:0007596; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0007229; GO:0016020; GO:0006911; GO:0007264,"Fc-gamma receptor signaling pathway involved in phagocytosis; GTPase activator activity; apoptotic process; axon guidance; blood coagulation; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; integrin-mediated signaling pathway; membrane; phagocytosis, engulfment; small GTPase mediated signal transduction",PF06920;PF14429;PF16172;PF14604;,,,,,,,,,DOCK1_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]" comp111723_c1_seq1,296,41.5541,0.78572325,12,3,,,,,,,,,8.00E-24,CHOYP_DOCK1.2.2,,,,,,,,, comp111726_c0_seq1,422,37.9147,0.35022551,9,48,,3.00E-43,Q3B8C3,Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein homolog),Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein homolog),GO:0005634,nucleus,,8.00E-13,CHOYP_NR2CA.1.1,,,,,,,NR2CA_XENLA,Xenopus laevis (African clawed frog), comp111730_c0_seq1,696,41.523,0.56900809,20,72,,4.00E-21,Q9CR23,Transmembrane protein 9,Transmembrane protein 9,GO:0016021; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0006810,integral to membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; transport,PF05434;,,,,,,,,,TMEM9_MOUSE,Mus musculus (Mouse),transport [GO:0006810] comp111749_c0_seq1,294,39.1156,0.53636984,24,66,,,,,,,,,,,3.00E-20,ruditapes_c19336,,,,,,, comp111752_c0_seq1,405,43.7037,0.50525751,13,13,,7.00E-42,Q768S4,Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein),Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein),GO:0006887; GO:0042593; GO:0006886; GO:0046872; GO:0045744; GO:0050714; GO:0017158; GO:0042493; GO:0030667; GO:0030658,exocytosis; glucose homeostasis; intracellular protein transport; metal ion binding; negative regulation of G-protein coupled receptor protein signaling pathway; positive regulation of protein secretion; regulation of calcium ion-dependent exocytosis; response to drug; secretory granule membrane; transport vesicle membrane,PF02318;,1.00E-48,CHOYP_LOC100549486.1.1,,,,,,,RPH3L_MOUSE,Mus musculus (Mouse),exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; positive regulation of protein secretion [GO:0050714]; regulation of calcium ion-dependent exocytosis [GO:0017158]; response to drug [GO:0042493]; vesicle fusion [GO:0006906] comp111752_c1_seq1,772,46.7617,0.5704105,16,32,,4.00E-35,Q14184,Double C2-like domain-containing protein beta (Doc2-beta),Double C2-like domain-containing protein beta (Doc2-beta),GO:0048791; GO:0005544; GO:0005737; GO:0015630; GO:0005886; GO:0045956; GO:0032024; GO:0031340; GO:0008104; GO:0008021; GO:0005215,calcium ion-dependent exocytosis of neurotransmitter; calcium-dependent phospholipid binding; cytoplasm; microtubule cytoskeleton; plasma membrane; positive regulation of calcium ion-dependent exocytosis; positive regulation of insulin secretion; positive regulation of vesicle fusion; protein localization; synaptic vesicle; transporter activity,PF00168;,,,,,,,,,DOC2B_HUMAN,Homo sapiens (Human),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906] comp111767_c0_seq1,628,38.6943,0.68369739,28,34,,4.00E-24,Q3UFS0,Protein zyg-11 homolog B,Protein zyg-11 homolog B,,,,6.00E-36,CHOYP_ISCW_ISCW018108.1.1,,,,,,,ZY11B_MOUSE,Mus musculus (Mouse),regulation of ubiquitin-protein transferase activity [GO:0051438] comp111769_c0_seq1,420,45,0.57422467,7,44,,4.00E-13,Q9LJN4,Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),GO:0005975; GO:0005618; GO:0004553; GO:0005578,"carbohydrate metabolic process; cell wall; hydrolase activity, hydrolyzing O-glycosyl compounds; proteinaceous extracellular matrix",PF14310;PF00933;PF01915;,,,,,,,,,BXL5_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975] comp111802_c1_seq1,309,41.7476,0.22388294,6,2,,2.00E-11,Q7TMM8,Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.31) (ADP-ribosyltransferase diphtheria toxin-like 15) (ARTD15) (Poly [ADP-ribose] polymerase 16) (PARP-16),Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16),GO:0003956; GO:0003950; GO:0005789; GO:0016021; GO:0031965; GO:0006986,NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; response to unfolded protein,PF00644;,,,,,,,,,PAR16_MOUSE,Mus musculus (Mouse),activation of signaling protein activity involved in unfolded protein response [GO:0006987]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of cell death [GO:0060548]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213] comp111810_c0_seq1,498,32.9317,0.37918086,23,0,,4.00E-14,Q9ERB4,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments),GO:0031103; GO:0005509; GO:0030246; GO:0007155; GO:0006928; GO:0031012; GO:0005540; GO:0030169; GO:0005578,axon regeneration; calcium ion binding; carbohydrate binding; cell adhesion; cellular component movement; extracellular matrix; hyaluronic acid binding; low-density lipoprotein particle binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_RAT,Rattus norvegicus (Rat),axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; response to wounding [GO:0009611]; skeletal system development [GO:0001501] comp111814_c1_seq1,684,41.6667,0.50780972,31,27,,2.00E-42,Q96JN8,Neuralized-like protein 4,Neuralized-like protein 4,GO:0005814,centriole,PF07177;,,,,,,,,,NEUL4_HUMAN,Homo sapiens (Human), comp111825_c0_seq1,1054,34.5351,0.43734095,1176,200,,1.00E-86,Q28FE4,MORN repeat-containing protein 5,MORN repeat-containing protein 5,,,PF02493;,1.00E-104,CHOYP_LOC586835.1.1,7.00E-124,ruditapes_c10305,5.00E-100,CU987413.p.cg.6,5,male gonad,MORN5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp111827_c2_seq1,382,46.3351,0.39484807,5,32,,3.00E-18,Q8BI17,SH2 domain-containing protein 7,SH2 domain-containing protein 7,,,PF00017;,7.00E-26,CHOYP_MYO3AL.1.1,,,,,,,SH2D7_MOUSE,Mus musculus (Mouse), comp111839_c0_seq1,461,34.0564,0.45073383,3,14,,1.00E-13,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp111839_c0_seq2,549,36.9763,0.48245774,4,24,,6.00E-12,Q6ZNA1,Zinc finger protein 836,Zinc finger protein 836,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN836_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp111848_c0_seq1,391,44.2455,0.33305231,16,32,,7.00E-11,O43639,Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta),Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta),GO:0042110; GO:0007015; GO:0007411; GO:0016477; GO:0008093; GO:0005829; GO:0005783; GO:0007173; GO:0030032; GO:0008285; GO:0042102; GO:0030838; GO:0045944; GO:0030159; GO:0007176; GO:0006417; GO:0007172; GO:0012506,T cell activation; actin filament organization; axon guidance; cell migration; cytoskeletal adaptor activity; cytosol; endoplasmic reticulum; epidermal growth factor receptor signaling pathway; lamellipodium assembly; negative regulation of cell proliferation; positive regulation of T cell proliferation; positive regulation of actin filament polymerization; positive regulation of transcription from RNA polymerase II promoter; receptor signaling complex scaffold activity; regulation of epidermal growth factor-activated receptor activity; regulation of translation; signal complex assembly; vesicle membrane,PF00017;PF00018;PF14604;,2.00E-44,CHOYP_PTN11.3.4,,,,,,,NCK2_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192] comp111848_c1_seq1,872,45.1835,0.58293346,33,54,,1.00E-104,Q06124,Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3),Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3),GO:0000077; GO:0038095; GO:0005070; GO:0031295; GO:0000187; GO:0036302; GO:0007411; GO:0007596; GO:0007420; GO:0005829; GO:0048013; GO:0007173; GO:0060325; GO:0008543; GO:0048806; GO:0042593; GO:0042445; GO:0009755; GO:0048839; GO:0008286; GO:0060333; GO:0050900; GO:0005739; GO:0048609; GO:0051463; GO:0060125; GO:0046676; GO:0048011; GO:0004726; GO:0005634; GO:0035265; GO:0048015; GO:2001275; GO:0046887; GO:0043234; GO:0033628; GO:0060334; GO:0040014; GO:0046825; GO:0060338; GO:0006641; GO:0060337,DNA damage checkpoint; Fc-epsilon receptor signaling pathway; SH3/SH2 adaptor activity; T cell costimulation; activation of MAPK activity; atrioventricular canal development; axon guidance; blood coagulation; brain development; cytosol; ephrin receptor signaling pathway; epidermal growth factor receptor signaling pathway; face morphogenesis; fibroblast growth factor receptor signaling pathway; genitalia development; glucose homeostasis; hormone metabolic process; hormone-mediated signaling pathway; inner ear development; insulin receptor signaling pathway; interferon-gamma-mediated signaling pathway; leukocyte migration; mitochondrion; multicellular organismal reproductive process; negative regulation of cortisol secretion; negative regulation of growth hormone secretion; negative regulation of insulin secretion; neurotrophin TRK receptor signaling pathway; non-membrane spanning protein tyrosine phosphatase activity; nucleus; organ growth; phosphatidylinositol-mediated signaling; positive regulation of glucose import in response to insulin stimulus; positive regulation of hormone secretion; protein complex; regulation of cell adhesion mediated by integrin; regulation of interferon-gamma-mediated signaling pathway; regulation of multicellular organism growth; regulation of protein export from nucleus; regulation of type I interferon-mediated signaling pathway; triglyceride metabolic process; type I interferon-mediated signaling pathway,PF00017;PF00102;,,,,,,,,,PTN11_HUMAN,Homo sapiens (Human),abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of hormone secretion [GO:0046887]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of multicellular organism growth [GO:0040014]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641] comp111865_c0_seq2,534,45.8801,0.60836334,17,0,,8.00E-48,Q05360,Protein white,Protein white,GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0031409; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; pigment binding; transport,PF01061;PF00005;,,,,,,,,,WHITE_LUCCU,Lucilia cuprina (Green bottle fly) (Australian sheep blowfly),transport [GO:0006810] comp111866_c0_seq1,512,48.4375,0.3408198,39,23,,3.00E-55,Q6NRC7,TBC1 domain family member 23,TBC1 domain family member 23,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF00581;,4.00E-56,CHOYP_LOC100375955.1.1,,,,,,,TBC23_XENLA,Xenopus laevis (African clawed frog), comp111886_c0_seq1,405,43.9506,1.02564728,0,72,,2.00E-44,Q8R5M0,PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3),PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3),,,PF00595;,4.00E-42,CHOYP_GIPC1.1.1,,,,,,,GIPC3_MOUSE,Mus musculus (Mouse), comp111886_c1_seq1,602,39.5349,0.66580971,7,191,,4.00E-49,Q9Z254,PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (GLUT1 C-terminal-binding protein) (GLUT1CBP) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1),PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (GLUT1 C-terminal-binding protein) (GLUT1CBP) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin),GO:0005903; GO:0005938; GO:0005829; GO:0043198; GO:0043197; GO:0030139; GO:0043542; GO:0014047; GO:0016020; GO:0032435; GO:0030511; GO:0006605; GO:0031647; GO:0048167; GO:0007268; GO:0008021; GO:0012506,brush border; cell cortex; cytosol; dendritic shaft; dendritic spine; endocytic vesicle; endothelial cell migration; glutamate secretion; membrane; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transforming growth factor beta receptor signaling pathway; protein targeting; regulation of protein stability; regulation of synaptic plasticity; synaptic transmission; synaptic vesicle; vesicle membrane,PF00595;,,,,,,,,,GIPC1_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; endothelial cell migration [GO:0043542]; glutamate secretion [GO:0014047]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of cytokinesis [GO:0032467]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting [GO:0006605]; regulation of protein stability [GO:0031647]; regulation of synaptic plasticity [GO:0048167] comp111889_c0_seq1,686,42.7114,0.80234684,34,28,,,,,,,,,,,2.00E-21,ruditapes_c17691,,,,,,, comp111899_c0_seq1,460,40.2174,0.86512255,9,21,,5.00E-16,O95479,GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)],GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)],GO:0017057; GO:0050661; GO:0030246; GO:0005788; GO:0047936; GO:0004345; GO:0005739; GO:0006098; GO:0097305,6-phosphogluconolactonase activity; NADP binding; carbohydrate binding; endoplasmic reticulum lumen; glucose 1-dehydrogenase [NAD(P)] activity; glucose-6-phosphate dehydrogenase activity; mitochondrion; pentose-phosphate shunt; response to alcohol,PF02781;PF00479;PF01182;,,,,,,,,,G6PE_HUMAN,Homo sapiens (Human),glucose metabolic process [GO:0006006]; pentose-phosphate shunt [GO:0006098] comp111902_c1_seq1,487,46.2012,0.50150409,6,64,,2.00E-46,A7RRG3,Protein AKTIP homolog (Fused toes protein homolog),Protein AKTIP homolog (Fused toes protein homolog),GO:0016881,acid-amino acid ligase activity,PF00179;,6.00E-15,CHOYP_BRAFLDRAFT_243769.1.1,,,,,,,AKTIP_NEMVE,Nematostella vectensis (Starlet sea anemone), comp111906_c0_seq1,834,42.446,0.50646521,44,9,,2.00E-34,Q8AYS7,Centromere protein I (CENP-I),Centromere protein I (CENP-I),GO:0034508; GO:0000776; GO:0005634,centromere complex assembly; kinetochore; nucleus,PF07778;,,,,,,,,,CENPI_CHICK,Gallus gallus (Chicken),centromere complex assembly [GO:0034508] comp111918_c2_seq1,505,43.3663,0.30144799,21,4,,1.00E-48,Q6UWE0,E3 ubiquitin-protein ligase LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL),E3 ubiquitin-protein ligase LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL),GO:0005737; GO:0005576; GO:0016020; GO:0045806; GO:0051865; GO:0030163; GO:0000209; GO:0015031; GO:0070086; GO:0004842; GO:0046755; GO:0008270,cytoplasm; extracellular region; membrane; negative regulation of endocytosis; protein autoubiquitination; protein catabolic process; protein polyubiquitination; protein transport; ubiquitin-dependent endocytosis; ubiquitin-protein ligase activity; viral budding; zinc ion binding,PF13855;PF07647;,3.00E-13,CHOYP_LOC100369519.1.1,,,,,,,LRSM1_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755] comp111937_c0_seq1,303,44.2244,0.54775371,7,0,,3.00E-56,O15945,Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango),Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango),GO:0007420; GO:0071456; GO:0032869; GO:0005737; GO:0048813; GO:0007425; GO:0008347; GO:0007517; GO:0000122; GO:0005634; GO:0048477; GO:0007422; GO:0045944; GO:0043234; GO:0046982; GO:0045676; GO:0043565; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"brain development; cellular response to hypoxia; cellular response to insulin stimulus; cytoplasm; dendrite morphogenesis; epithelial cell fate determination, open tracheal system; glial cell migration; muscle organ development; negative regulation of transcription from RNA polymerase II promoter; nucleus; oogenesis; peripheral nervous system development; positive regulation of transcription from RNA polymerase II promoter; protein complex; protein heterodimerization activity; regulation of R7 cell differentiation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;PF00989;,4.00E-66,CHOYP_ARNT.1.1,,,,,,,ARNT_DROME,Drosophila melanogaster (Fruit fly),"brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; epithelial cell fate determination, open tracheal system [GO:0007425]; glial cell migration [GO:0008347]; limb development [GO:0060173]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of R7 cell differentiation [GO:0045676]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]" comp111944_c0_seq1,810,43.4568,0.52454464,47,9,,2.00E-58,Q9UBZ9,DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase),DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase),GO:0006260; GO:0003887; GO:0003684; GO:0017125; GO:0042276; GO:0000287; GO:0005654; GO:0009411,DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; deoxycytidyl transferase activity; error-prone translesion synthesis; magnesium ion binding; nucleoplasm; response to UV,PF16589;PF14377;PF00817;PF11799;PF16727;,2.00E-43,CHOYP_BRAFLDRAFT_213587.1.1,,,,,,,REV1_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp111954_c0_seq1,377,33.4218,0.2857883,14,12,,9.00E-08,O94762,"ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)","ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)",GO:0005524; GO:0008026; GO:0003678; GO:0006310; GO:0006281; GO:0006260; GO:0016591; GO:0000993; GO:0051301; GO:0051304; GO:0005737; GO:0007067; GO:0034244; GO:0031965; GO:0003676; GO:0005730,"ATP binding; ATP-dependent helicase activity; DNA helicase activity; DNA recombination; DNA repair; DNA replication; DNA-directed RNA polymerase II, holoenzyme; RNA polymerase II core binding; cell division; chromosome separation; cytoplasm; mitosis; negative regulation of transcription elongation from RNA polymerase II promoter; nuclear membrane; nucleic acid binding; nucleolus",PF00270;PF00271;PF06959;PF16124;,,,,,,,,,RECQ5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244] comp111963_c1_seq1,432,40.0463,0.60340346,5,17,,5.00E-71,Q5RFB7,Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21),Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21),GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,9.00E-38,CHOYP_LOC100376719.1.1,,,,,,,ODC_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),transmembrane transport [GO:0055085] comp111973_c0_seq1,397,40.5542,0.55760005,15,28,,,,,,,,,,,2.00E-17,ruditapes_c20754,,,,,,, comp111991_c3_seq1,869,40.2762,0.65701427,38,40,,1.00E-19,Q9NA13,"Inositol 1,4,5-trisphosphate receptor-like protein A","Inositol 1,4,5-trisphosphate receptor-like protein A",GO:0048102; GO:0030244; GO:0034670; GO:0005783; GO:0005789; GO:0005220; GO:0016021; GO:0051209,"autophagic cell death; cellulose biosynthetic process; chemotaxis to arachidonic acid; endoplasmic reticulum; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; release of sequestered calcium ion into cytosol",PF08454;PF01365;,1.00E-84,CHOYP_LOC100375107.1.4,,,,,,,IPLA_DICDI,Dictyostelium discoideum (Slime mold),aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209] comp111993_c0_seq1,526,41.8251,0.49382579,2,60,,4.00E-11,Q499M4,Tigger transposable element derived 5,Tigger transposable element derived 5,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD5_MOUSE,Mus musculus (Mouse), comp112007_c0_seq1,493,48.4787,0.48622247,51,38,,6.00E-32,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp112010_c0_seq1,205,46.8293,0.87952757,2,9,,2.00E-11,O34736,Uncharacterized oxidoreductase YjmC (EC 1.1.1.-),Uncharacterized oxidoreductase YjmC (EC 1.1.1.-),GO:0005737; GO:0016491,cytoplasm; oxidoreductase activity,PF02615;,,,,,,,,,YJMC_BACSU,Bacillus subtilis (strain 168), comp112010_c1_seq1,254,46.8504,0.44348513,0,12,,2.00E-21,O59028,Malate dehydrogenase (EC 1.1.1.37),Malate dehydrogenase (EC 1.1.1.37),GO:0030060; GO:0005737; GO:0006099,L-malate dehydrogenase activity; cytoplasm; tricarboxylic acid cycle,PF02615;,1.00E-20,CHOYP_CRE_02254.1.1,,,,,,,MDH_PYRHO,Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3),tricarboxylic acid cycle [GO:0006099] comp112022_c0_seq1,406,44.5813,0.29824314,19,0,,3.00E-25,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,2.00E-15,CHOYP_LOC591417.2.2,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp112036_c0_seq1,419,40.5728,0.81940266,28,0,,4.00E-20,P42336,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)",GO:0016303; GO:0035005; GO:0005943; GO:0005524; GO:0038095; GO:0038096; GO:0031295; GO:0050852; GO:0001525; GO:0060048; GO:0043542; GO:0007173; GO:0008543; GO:0006006; GO:0044029; GO:0045087; GO:0038028; GO:0030027; GO:0050900; GO:2000811; GO:0048011; GO:0046934; GO:0048015; GO:0005886; GO:0030168; GO:0033138; GO:0043491; GO:0030295; GO:0004674; GO:2000653; GO:0040014; GO:0044281; GO:0001944,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ATP binding; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell costimulation; T cell receptor signaling pathway; angiogenesis; cardiac muscle contraction; endothelial cell migration; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; glucose metabolic process; hypomethylation of CpG island; innate immune response; insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; lamellipodium; leukocyte migration; negative regulation of anoikis; neurotrophin TRK receptor signaling pathway; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; phosphatidylinositol-mediated signaling; plasma membrane; platelet activation; positive regulation of peptidyl-serine phosphorylation; protein kinase B signaling cascade; protein kinase activator activity; protein serine/threonine kinase activity; regulation of genetic imprinting; regulation of multicellular organism growth; small molecule metabolic process; vasculature development",PF00454;PF00792;PF02192;PF00794;PF00613;,8.00E-13,CHOYP_PK3CA.1.1,,,,,,,PK3CA_HUMAN,Homo sapiens (Human),adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cardiac muscle contraction [GO:0060048]; cellular response to glucose stimulus [GO:0071333]; endothelial cell migration [GO:0043542]; energy homeostasis [GO:0097009]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; leukocyte migration [GO:0050900]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculature development [GO:0001944] comp112038_c0_seq1,829,41.737,0.61606028,4,107,,8.00E-87,Q9BQG2,Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12),Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12),GO:0019677; GO:0000210; GO:0035529; GO:0006742; GO:0046872; GO:0005634; GO:0005777,NAD catabolic process; NAD+ diphosphatase activity; NADH pyrophosphatase activity; NADP catabolic process; metal ion binding; nucleus; peroxisome,PF12796;PF00293;PF09296;PF09297;,2.00E-82,CHOYP_BRAFLDRAFT_115611.1.1,1.00E-82,ruditapes_c19537,,,,,NUD12_HUMAN,Homo sapiens (Human),NAD catabolic process [GO:0019677]; NADP catabolic process [GO:0006742]; nicotinamide metabolic process [GO:0006769] comp112042_c1_seq1,517,39.0716,0.91726856,13,29,,2.00E-12,Q86Z23,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_HUMAN,Homo sapiens (Human),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp112084_c0_seq1,375,46.4,0.49841288,17,2,,3.00E-17,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,,,,,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp112088_c1_seq1,416,44.9519,0.67632458,0,41,,1.00E-16,Q24372,Lachesin,Lachesin,GO:0031225; GO:0061343; GO:0007156; GO:0035160; GO:0016331; GO:0005886; GO:0042803; GO:0035151; GO:0005918; GO:0019991,"anchored to membrane; cell adhesion involved in heart morphogenesis; homophilic cell adhesion; maintenance of epithelial integrity, open tracheal system; morphogenesis of embryonic epithelium; plasma membrane; protein homodimerization activity; regulation of tube size, open tracheal system; septate junction; septate junction assembly",PF07679;,,,,,,,,,LACH_DROME,Drosophila melanogaster (Fruit fly),"cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]" comp112092_c0_seq1,481,41.7879,0.52714485,13,26,,3.00E-15,O15228,Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase),Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase),GO:0021587; GO:0008611; GO:0016287; GO:0005739; GO:0016290; GO:0030913; GO:0005782; GO:0005778; GO:0006654; GO:0042493; GO:0070542; GO:0007584; GO:0042594; GO:0007416,cerebellum morphogenesis; ether lipid biosynthetic process; glycerone-phosphate O-acyltransferase activity; mitochondrion; palmitoyl-CoA hydrolase activity; paranodal junction assembly; peroxisomal matrix; peroxisomal membrane; phosphatidic acid biosynthetic process; response to drug; response to fatty acid; response to nutrient; response to starvation; synapse assembly,PF01553;,,,1.00E-16,ruditapes_c35062,,,,,GNPAT_HUMAN,Homo sapiens (Human),cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; membrane organization [GO:0061024]; paranodal junction assembly [GO:0030913]; phosphatidic acid biosynthetic process [GO:0006654]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; synapse assembly [GO:0007416] comp112092_c1_seq1,579,39.2055,0.45669428,9,37,,,,,,,,,3.00E-13,CHOYP_LOC590838.1.1,,,,,,,,, comp112104_c0_seq2,1322,40.7716,0.5286607,6,246,,2.00E-42,O16025,Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],GO:0047677; GO:0019369; GO:0004096; GO:0005737; GO:0020037; GO:0047987; GO:0005506; GO:0016020; GO:0031408,arachidonate 8(R)-lipoxygenase activity; arachidonic acid metabolic process; catalase activity; cytoplasm; heme binding; hydroperoxide dehydratase activity; iron ion binding; membrane; oxylipin biosynthetic process,PF00305;PF01477;,5.00E-85,CHOYP_LOC584481.5.10,,,,,,,AOSL_PLEHO,Plexaura homomalla (Black sea rod),arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408] comp112107_c0_seq2,603,37.8109,0.42221475,0,0,,,,,,,,,7.00E-16,CHOYP_TEN4.1.1,,,,,,,,, comp112107_c0_seq3,788,42.2589,0.74031155,0,0,,,,,,,,,7.00E-17,CHOYP_TEN2.1.2,,,,,,,,, comp112107_c0_seq7,499,38.0762,0.50539287,0,0,,,,,,,,,5.00E-16,CHOYP_TEN4.1.1,,,,,,,,, comp112113_c1_seq2,498,42.9719,0.61670446,9,14,,6.00E-23,Q8C3J5,Dedicator of cytokinesis protein 2 (Protein Hch),Dedicator of cytokinesis protein 2 (Protein Hch),GO:0030675; GO:0030676; GO:0042608; GO:0046633; GO:0006935; GO:0005737; GO:0005856; GO:0007010; GO:0012505; GO:0001768; GO:0001771; GO:0044351; GO:0016020; GO:0001766; GO:0002277; GO:0045060; GO:0035022; GO:0050766; GO:0045059; GO:0007264,Rac GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; alpha-beta T cell proliferation; chemotaxis; cytoplasm; cytoskeleton; cytoskeleton organization; endomembrane system; establishment of T cell polarity; immunological synapse formation; macropinocytosis; membrane; membrane raft polarization; myeloid dendritic cell activation involved in immune response; negative thymic T cell selection; positive regulation of Rac protein signal transduction; positive regulation of phagocytosis; positive thymic T cell selection; small GTPase mediated signal transduction,PF06920;PF14429;PF16172;PF00018;,,,,,,,,,DOCK2_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; alpha-beta T cell activation [GO:0046631]; alpha-beta T cell proliferation [GO:0046633]; chemotaxis [GO:0006935]; cytoskeleton organization [GO:0007010]; establishment of T cell polarity [GO:0001768]; immunological synapse formation [GO:0001771]; macropinocytosis [GO:0044351]; membrane raft polarization [GO:0001766]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative thymic T cell selection [GO:0045060]; positive regulation of phagocytosis [GO:0050766]; positive regulation of Rac protein signal transduction [GO:0035022]; positive thymic T cell selection [GO:0045059]; small GTPase mediated signal transduction [GO:0007264]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098] comp112120_c1_seq1,349,46.9914,0.42715835,5,4,,4.00E-28,A5PJM7,Differentially expressed in FDCP 8 homolog (DEF-8),Differentially expressed in FDCP 8 homolog (DEF-8),GO:0035556; GO:0008270,intracellular signal transduction; zinc ion binding,PF00130;PF13901;,7.00E-19,CHOYP_DFI8A.1.1,,,,,,,DEFI8_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556] comp112133_c0_seq1,552,43.6594,0.30481015,0,0,,4.00E-10,Q6BMV2,Palmitoyltransferase PFA3 (EC 2.3.1.225) (Protein fatty acyltransferase 3),Palmitoyltransferase PFA3 (EC 2.3.1.225) (Protein fatty acyltransferase 3),GO:0016021; GO:0016746; GO:0005774; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; vacuolar membrane; zinc ion binding",PF01529;,1.00E-12,CHOYP_LOC100710792.1.1,,,,,,,PFA3_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),"protein palmitoylation [GO:0018345]; vacuole fusion, non-autophagic [GO:0042144]" comp112133_c0_seq2,796,42.0854,0.42675158,11,19,,6.00E-35,A2VDT6,Probable palmitoyltransferase ZDHHC21 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 21) (DHHC-21),Probable palmitoyltransferase ZDHHC21 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 21) (DHHC-21),GO:0005794; GO:0016021; GO:0018230; GO:0016746; GO:0008270,"Golgi apparatus; integral to membrane; peptidyl-L-cysteine S-palmitoylation; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,6.00E-12,CHOYP_PHUM_PHUM003160.1.1,,,,,,,ZDH21_BOVIN,Bos taurus (Bovine),hair follicle development [GO:0001942]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; sebaceous gland development [GO:0048733] comp112138_c0_seq2,549,48.0874,0.34772229,3,21,,1.00E-19,Q91WC9,Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-),Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-),GO:0019369; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0004806,arachidonic acid metabolic process; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; triglyceride lipase activity,PF01764;,,,,,,,,,DGLB_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136] comp112142_c0_seq1,398,41.206,0.42044523,12,36,,5.00E-20,P34694,Transcription factor IIIA (TFIIIA),Transcription factor IIIA (TFIIIA),GO:0003677; GO:0003723; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; RNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,TF3A_ANAAE,Anaxyrus americanus (American toad) (Bufo americanus),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp11215_c0_seq1,242,47.9339,0.43393598,4,0,,7.00E-10,Q7Z304,MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan),MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan),GO:0005783; GO:0005539; GO:0005614; GO:0016020; GO:0019800,endoplasmic reticulum; glycosaminoglycan binding; interstitial matrix; membrane; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan,PF00629;,,,,,,,,,MAMC2_HUMAN,Homo sapiens (Human), comp112161_c0_seq1,676,39.9408,0.78629673,59,0,,,,,,,,,7.00E-61,CHOYP_RGD1309762.1.1,,,,,,,,, comp112181_c0_seq1,452,44.2478,0.9521616,1,39,,1.00E-44,Q9EP75,Leukotriene-B4 omega-hydroxylase 3 (EC 1.14.13.30) (Cyp4f-14) (Cytochrome P450 4F14) (Cytochrome P450-LTB-omega) (Leukotriene-B4 20-monooxygenase 3),Leukotriene-B4 omega-hydroxylase 3 (EC 1.14.13.30) (Cyp4f-14) (Cytochrome P450 4F14) (Cytochrome P450-LTB-omega) (Leukotriene-B4 20-monooxygenase 3),GO:0052871; GO:0005789; GO:0020037; GO:0005506; GO:0036101; GO:0050051,alpha-tocopherol omega-hydroxylase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; leukotriene B4 catabolic process; leukotriene-B4 20-monooxygenase activity,PF00067;,8.00E-20,CHOYP_LOC100562694.1.1,7.00E-12,ruditapes_c13541,,,,,CP4FE_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; response to toxic substance [GO:0009636] comp112183_c0_seq1,442,44.3439,1.01648414,5,33,,1.00E-39,O81884,L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316),L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316),GO:0019853; GO:0010349; GO:0005829; GO:0006012,L-ascorbic acid biosynthetic process; L-galactose dehydrogenase activity; cytosol; galactose metabolic process,PF00248;,7.00E-27,CHOYP_BRAFLDRAFT_67662.1.1,,,,,,,GALDH_ARATH,Arabidopsis thaliana (Mouse-ear cress),galactose metabolic process [GO:0006012]; L-ascorbic acid biosynthetic process [GO:0019853] comp112183_c1_seq1,505,45.3465,0.69580105,12,25,,2.00E-26,O81884,L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316),L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316),GO:0019853; GO:0010349; GO:0005829; GO:0006012,L-ascorbic acid biosynthetic process; L-galactose dehydrogenase activity; cytosol; galactose metabolic process,PF00248;,,,1.00E-35,ruditapes_c20997,,,,,GALDH_ARATH,Arabidopsis thaliana (Mouse-ear cress),galactose metabolic process [GO:0006012]; L-ascorbic acid biosynthetic process [GO:0019853] comp112187_c0_seq1,354,42.0904,0.45116555,8,4,,3.00E-32,Q64640,Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase),Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase),GO:0044209; GO:0005524; GO:0004001; GO:0046085; GO:0032922; GO:0005737; GO:0005829; GO:0006175; GO:0046872; GO:0005634; GO:0016773; GO:0042102; GO:0010613; GO:0006166; GO:0044342,"AMP salvage; ATP binding; adenosine kinase activity; adenosine metabolic process; circadian regulation of gene expression; cytoplasm; cytosol; dATP biosynthetic process; metal ion binding; nucleus; phosphotransferase activity, alcohol group as acceptor; positive regulation of T cell proliferation; positive regulation of cardiac muscle hypertrophy; purine ribonucleoside salvage; type B pancreatic cell proliferation",PF00294;,,,,,,,,,ADK_RAT,Rattus norvegicus (Rat),adenosine metabolic process [GO:0046085]; AMP salvage [GO:0044209]; circadian regulation of gene expression [GO:0032922]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine ribonucleoside salvage [GO:0006166]; type B pancreatic cell proliferation [GO:0044342] comp112187_c1_seq1,311,44.0514,0.28235586,6,6,,1.00E-26,Q9LZG0,Adenosine kinase 2 (AK 2) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase 2),Adenosine kinase 2 (AK 2) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase 2),GO:0044209; GO:0005524; GO:0004001; GO:0006169; GO:0005507; GO:0005829; GO:0019048; GO:0016773; GO:0005886,"AMP salvage; ATP binding; adenosine kinase activity; adenosine salvage; copper ion binding; cytosol; modulation by virus of host morphology or physiology; phosphotransferase activity, alcohol group as acceptor; plasma membrane",PF00294;,,,,,,,,,ADK2_ARATH,Arabidopsis thaliana (Mouse-ear cress),adenosine salvage [GO:0006169]; AMP salvage [GO:0044209]; viral process [GO:0016032] comp112189_c0_seq1,217,43.318,0.29822795,11,10,,,,,,,,,3.00E-39,CHOYP_LOC100372028.1.1,,,,,,,,, comp112189_c1_seq1,389,44.7301,0.30981272,10,21,,1.00E-33,Q86UW7,Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2),Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2),GO:0030054; GO:0030659; GO:0046872; GO:0005543; GO:0045921; GO:0045211; GO:0042734; GO:0015031; GO:0016082,cell junction; cytoplasmic vesicle membrane; metal ion binding; phospholipid binding; positive regulation of exocytosis; postsynaptic membrane; presynaptic membrane; protein transport; synaptic vesicle priming,PF06292;PF00169;,3.00E-74,CHOYP_LOC100372028.1.1,,,,,,,CAPS2_HUMAN,Homo sapiens (Human),cellular response to starvation [GO:0009267]; dense core granule exocytosis [GO:1990504]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; synaptic vesicle priming [GO:0016082] comp112198_c0_seq2,336,45.2381,0.52656716,0,14,,,,,,,,,2.00E-18,CHOYP_LOC663736.2.2,,,,,,,,, comp112199_c1_seq1,504,40.2778,0.87638156,10,32,,3.00E-30,P50133,Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor),Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor),GO:0007189; GO:0007188; GO:0030282; GO:0045453; GO:0048469; GO:0006874; GO:0002062; GO:0005887; GO:0005622; GO:0008285; GO:0002076; GO:0004991; GO:0017046; GO:0007200; GO:0008284; GO:0043621,adenylate cyclase-activating G-protein coupled receptor signaling pathway; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; bone mineralization; bone resorption; cell maturation; cellular calcium ion homeostasis; chondrocyte differentiation; integral to plasma membrane; intracellular; negative regulation of cell proliferation; osteoblast development; parathyroid hormone receptor activity; peptide hormone binding; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of cell proliferation; protein self-association,PF00002;PF02793;,,,,,,,,,PTH1R_PIG,Sus scrofa (Pig),adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; bone mineralization [GO:0030282]; bone resorption [GO:0045453]; cell maturation [GO:0048469]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; chondrocyte differentiation [GO:0002062]; negative regulation of cell proliferation [GO:0008285]; osteoblast development [GO:0002076]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cell proliferation [GO:0008284] comp112206_c0_seq1,428,37.1495,0.6809561,5,35,,5.00E-10,O13089,DNA-binding protein Ikaros (Ikaros family zinc finger protein 1),DNA-binding protein Ikaros (Ikaros family zinc finger protein 1),GO:0003677; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,IKZF1_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),"multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp112213_c0_seq1,568,47.1831,0.90548732,22,36,,4.00E-66,P49221,Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Fibrinoligase) (Prostate transglutaminase) (Prostate-specific transglutaminase) (Transglutaminase P) (TG(P)) (TGP) (TGase P) (Transglutaminase-4) (TGase-4),Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Fibrinoligase) (Prostate transglutaminase) (Prostate-specific transglutaminase) (Transglutaminase P) (TG(P)) (TGP) (TGase P) (Transglutaminase-4) (TGase-4),GO:0046872; GO:0018149; GO:0018184; GO:0003810,metal ion binding; peptide cross-linking; protein polyamination; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,TGM4_HUMAN,Homo sapiens (Human),peptide cross-linking [GO:0018149] comp112218_c1_seq1,520,35.7692,0.36247815,10,126,,,,,,,,,,,3.00E-11,ruditapes_c25723,,,,,,, comp112220_c0_seq2,740,43.2432,0.37807675,21,38,,5.00E-50,P59015,Vacuolar protein sorting-associated protein 18 homolog,Vacuolar protein sorting-associated protein 18 homolog,GO:0045176; GO:0015721; GO:0008333; GO:0043485; GO:0048069; GO:0006886; GO:0031902; GO:0005765; GO:0060036; GO:0007634; GO:0016192; GO:0008270,apical protein localization; bile acid and bile salt transport; endosome to lysosome transport; endosome to pigment granule transport; eye pigmentation; intracellular protein transport; late endosome membrane; lysosomal membrane; notochord cell vacuolation; optokinetic behavior; vesicle-mediated transport; zinc ion binding,PF00637;PF05131;,2.00E-54,CHOYP_VPS18.1.1,,,,,,,VPS18_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; pigment granule maturation [GO:0048757]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904] comp112222_c1_seq1,925,33.5135,0.70326229,103,49,,1.00E-08,Q3B8E8,N-acetylneuraminate lyase A (NALase A) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase A) (N-acetylneuraminic acid aldolase A) (Sialate lyase A) (Sialate-pyruvate lyase A) (Sialic acid aldolase A) (Sialic acid lyase A),N-acetylneuraminate lyase A (NALase A) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase A) (N-acetylneuraminic acid aldolase A) (Sialate lyase A) (Sialate-pyruvate lyase A) (Sialic acid aldolase A) (Sialic acid lyase A),GO:0019262; GO:0008747; GO:0005975; GO:0005737,N-acetylneuraminate catabolic process; N-acetylneuraminate lyase activity; carbohydrate metabolic process; cytoplasm,PF00701;,,,,,,,,,NPLA_XENLA,Xenopus laevis (African clawed frog),carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262] comp112227_c0_seq4,916,46.0699,0.9894583,0,0,,,,,,,,,4.00E-14,CHOYP_contig_009255,,,,,,,,, comp112237_c0_seq1,240,45,0.24828728,4,19,,2.00E-30,Q8N0X4,"Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (EC 4.1.-.-)","Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (Beta-methylmalate synthase) (EC 2.3.3.-) (Malate synthase) (EC 2.3.3.9)",GO:0006725; GO:0008815; GO:0009346; GO:0046872; GO:0005739,cellular aromatic compound metabolic process; citrate (pro-3S)-lyase activity; citrate lyase complex; metal ion binding; mitochondrion,PF03328;,1.00E-26,CHOYP_LOC100700757.1.1,,,,,,,CLYBL_HUMAN,Homo sapiens (Human), comp112245_c1_seq1,407,38.5749,0.46773948,1,31,,2.00E-15,P17019,Zinc finger protein 708 (Zinc finger protein 15) (Zinc finger protein 15-like 1) (Zinc finger protein KOX8),Zinc finger protein 708 (Zinc finger protein 15) (Zinc finger protein 15-like 1) (Zinc finger protein KOX8),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,1.00E-11,CHOYP_LOC100142269.1.1,,,,,,,ZN708_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp112257_c0_seq1,487,42.0945,0.52136972,16,20,,8.00E-83,O76924,Protein ariadne-2 (Ari-2),Protein ariadne-2 (Ari-2),GO:0003676; GO:0005634; GO:0008270,nucleic acid binding; nucleus; zinc ion binding,PF01485;,2.00E-117,CHOYP_ARI2.1.1,,,,,,,ARI2_DROME,Drosophila melanogaster (Fruit fly),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp112270_c0_seq1,219,44.2922,1.069872,5,0,,2.00E-06,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp112275_c0_seq1,670,42.6866,0.95626534,3,0,,6.00E-42,P47990,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0030151; GO:0043546; GO:0005777; GO:0034418; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; peroxisome; urate biosynthetic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,2.00E-16,CHOYP_XDH.3.3,,,,,,,XDH_CHICK,Gallus gallus (Chicken),urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] comp112276_c3_seq1,285,40.3509,0.53061878,5,0,,,,,,,,,,,1.00E-11,ruditapes_c1831,,,,,,, comp112279_c0_seq1,479,46.5553,0.63335259,11,26,,2.00E-25,Q08D51,Autophagy-related protein 2 homolog A,Autophagy-related protein 2 homolog A,GO:0006914,autophagy,PF13329;PF09333;PF12624;,4.00E-17,CHOYP_ATG2A.1.1,,,,,,,ATG2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp112311_c0_seq1,770,44.026,0.90006519,41,42,,6.00E-49,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp112313_c0_seq1,460,43.913,0.41255042,8,3,,6.00E-52,P97698,Smoothened homolog (SMO),Smoothened homolog (SMO),GO:0004930; GO:0030165; GO:0042813; GO:0017147; GO:0021984; GO:0048846; GO:0044295; GO:0060070; GO:0010002; GO:0021953; GO:0021696; GO:0060830; GO:0005929; GO:0005737; GO:0044294; GO:0003140; GO:0021904; GO:0008144; GO:0031076; GO:0048557; GO:0048702; GO:0048703; GO:0031017; GO:0021561; GO:0021508; GO:0048853; GO:0008406; GO:0001947; GO:0016021; GO:0072285; GO:0007494; GO:0042693; GO:0043392; GO:0043066; GO:0010629; GO:0001755; GO:0048663; GO:0031102; GO:0043025; GO:0042475; GO:0001649; GO:0033687; GO:0032474; GO:0005886; GO:0090190; GO:0050679; GO:0010628; GO:0007228; GO:0002053; GO:0002052; GO:0045880; GO:0014069; GO:0010033; GO:0009611; GO:0048752; GO:0021938; GO:0021910; GO:0061053; GO:0007283; GO:0001570,G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; adenohypophysis development; axon extension involved in axon guidance; axonal growth cone; canonical Wnt receptor signaling pathway; cardioblast differentiation; central nervous system neuron differentiation; cerebellar cortex morphogenesis; ciliary receptor clustering involved in smoothened signaling pathway; cilium; cytoplasm; dendritic growth cone; determination of left/right asymmetry in lateral mesoderm; dorsal/ventral neural tube patterning; drug binding; embryonic camera-type eye development; embryonic digestive tract morphogenesis; embryonic neurocranium morphogenesis; embryonic viscerocranium morphogenesis; exocrine pancreas development; facial nerve development; floor plate formation; forebrain morphogenesis; gonad development; heart looping; integral to membrane; mesenchymal to epithelial transition involved in metanephric renal vesicle formation; midgut development; muscle cell fate commitment; negative regulation of DNA binding; negative regulation of apoptotic process; negative regulation of gene expression; neural crest cell migration; neuron fate commitment; neuron projection regeneration; neuronal cell body; odontogenesis of dentin-containing tooth; osteoblast differentiation; osteoblast proliferation; otolith morphogenesis; plasma membrane; positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of epithelial cell proliferation; positive regulation of gene expression; positive regulation of hh target transcription factor activity; positive regulation of mesenchymal cell proliferation; positive regulation of neuroblast proliferation; positive regulation of smoothened signaling pathway; postsynaptic density; response to organic substance; response to wounding; semicircular canal morphogenesis; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; smoothened signaling pathway involved in ventral spinal cord patterning; somite development; spermatogenesis; vasculogenesis,PF01534;PF01392;,7.00E-27,CHOYP_SMO.1.1,,,,,,,SMO_RAT,Rattus norvegicus (Rat),axon extension involved in axon guidance [GO:0048846]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; facial nerve development [GO:0021561]; forebrain morphogenesis [GO:0048853]; heart looping [GO:0001947]; mesenchymal to epithelial transition involved in metanephric renal vesicle formation [GO:0072285]; midgut development [GO:0007494]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; neuron projection regeneration [GO:0031102]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; response to organic substance [GO:0010033]; response to wounding [GO:0009611]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; spermatogenesis [GO:0007283] comp112328_c0_seq1,924,45.9957,0.61530946,35,64,,6.00E-123,P49696,Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),GO:0005524; GO:0002161; GO:0005737; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00043;PF00133;PF10458;,6.00E-38,CHOYP_BRAFLDRAFT_66627.1.1,,,,,,,SYVC_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),valyl-tRNA aminoacylation [GO:0006438] comp112330_c0_seq1,560,49.1071,0.51180801,16,19,,3.00E-42,Q9W4S9,"cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G (EC 3.1.4.53) (Learning/memory process protein) (Protein dunce)","cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G (EC 3.1.4.53) (Learning/memory process protein) (Protein dunce)",GO:0004114; GO:0048675; GO:0048149; GO:0006198; GO:0019933; GO:0001661; GO:0007619; GO:0046331; GO:0045475; GO:0046872; GO:0046958; GO:0008355; GO:0048477; GO:0007614; GO:0007268; GO:0040040,"3',5'-cyclic-nucleotide phosphodiesterase activity; axon extension; behavioral response to ethanol; cAMP catabolic process; cAMP-mediated signaling; conditioned taste aversion; courtship behavior; lateral inhibition; locomotor rhythm; metal ion binding; nonassociative learning; olfactory learning; oogenesis; short-term memory; synaptic transmission; thermosensory behavior",PF00233;,3.00E-19,CHOYP_LOC100874620.1.1,,,,,,,PDE4C_DROME,Drosophila melanogaster (Fruit fly),associative learning [GO:0008306]; axon extension [GO:0048675]; behavioral response to ethanol [GO:0048149]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; conditioned taste aversion [GO:0001661]; courtship behavior [GO:0007619]; cyclic nucleotide metabolic process [GO:0009187]; lateral inhibition [GO:0046331]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; mating behavior [GO:0007617]; memory [GO:0007613]; nonassociative learning [GO:0046958]; olfactory learning [GO:0008355]; oogenesis [GO:0048477]; regulation of protein kinase A signaling [GO:0010738]; reproduction [GO:0000003]; short-term memory [GO:0007614]; thermosensory behavior [GO:0040040] comp112334_c0_seq2,804,43.7811,0.4882083,24,28,,1.00E-70,Q5BKM3,Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Vacuolar protein-sorting-associated protein 24),Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Vacuolar protein-sorting-associated protein 24),GO:0005829; GO:0031902; GO:0015031,cytosol; late endosome membrane; protein transport,PF03357;,7.00E-74,CHOYP_CHMP3.1.1,,,,,,,CHMP3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp112344_c0_seq1,254,50,0.25564306,10,7,,1.00E-22,Q86YT6,E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (Zinc finger ZZ type with ankyrin repeat domain protein 2),E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (Zinc finger ZZ type with ankyrin repeat domain protein 2),GO:0007219; GO:0001568; GO:0005813; GO:0031410; GO:0005829; GO:0001947; GO:0001701; GO:0045665; GO:0001841; GO:0031965; GO:0005886; GO:0045807; GO:0001756; GO:0004842; GO:0008270,Notch signaling pathway; blood vessel development; centrosome; cytoplasmic vesicle; cytosol; heart looping; in utero embryonic development; negative regulation of neuron differentiation; neural tube formation; nuclear membrane; plasma membrane; positive regulation of endocytosis; somitogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,1.00E-57,CHOYP_MIB1.3.4,,,,,,,MIB1_HUMAN,Homo sapiens (Human),blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756] comp112369_c1_seq1,226,45.5752,1.02716943,8,11,,,,,,,,,1.00E-12,CHOYP_BRAFLDRAFT_117849.3.3,,,,,,,,, comp112369_c2_seq1,1308,41.055,0.82056438,33,45,,,,,,,,,2.00E-14,CHOYP_BRAFLDRAFT_117849.2.3,,,,,,,,, comp112372_c0_seq1,530,42.4528,0.96591612,20,26,,4.00E-22,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp112394_c0_seq1,423,39.4799,1.03415212,13,6,,1.00E-08,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp112395_c0_seq1,705,43.4043,0.60329111,0,0,,2.00E-06,Q63518,"Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform) (Fragment)","Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform) (Fragment)",GO:0007155; GO:0006936; GO:0017022; GO:0032982,cell adhesion; muscle contraction; myosin binding; myosin filament,PF00041;PF07679;,,,,,,,,,MYPC1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155]; muscle contraction [GO:0006936] comp112395_c0_seq2,789,43.2193,0.54355392,2,8,,2.00E-16,Q9P232,Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein),Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein),GO:0031225; GO:0007155; GO:0007399; GO:0005886,anchored to membrane; cell adhesion; nervous system development; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN3_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; nervous system development [GO:0007399] comp112396_c0_seq2,535,40.3738,1.10297907,9,33,,1.00E-06,Q9R1B9,Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product],Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product],GO:0005095; GO:0061364; GO:0048846; GO:0048754; GO:0005509; GO:0002042; GO:0009986; GO:0016337; GO:0071504; GO:0032870; GO:0045499; GO:0021836; GO:0021972; GO:0005737; GO:0033563; GO:0005615; GO:0008201; GO:0001701; GO:0050929; GO:0060763; GO:0001656; GO:0008045; GO:0030837; GO:0030308; GO:0008285; GO:0090288; GO:0070100; GO:0010596; GO:0010629; GO:0010593; GO:0071676; GO:0090024; GO:0001933; GO:0090260; GO:0051058; GO:0071672; GO:0043116; GO:0021772; GO:0043065; GO:0005102; GO:0051414; GO:0031290; GO:0022029; GO:0001657,GTPase inhibitor activity; apoptotic process involved in luteolysis; axon extension involved in axon guidance; branching morphogenesis of an epithelial tube; calcium ion binding; cell migration involved in sprouting angiogenesis; cell surface; cell-cell adhesion; cellular response to heparin; cellular response to hormone stimulus; chemorepellent activity; chemorepulsion involved in postnatal olfactory bulb interneuron migration; corticospinal neuron axon guidance through spinal cord; cytoplasm; dorsal/ventral axon guidance; extracellular space; heparin binding; in utero embryonic development; induction of negative chemotaxis; mammary duct terminal end bud growth; metanephros development; motor neuron axon guidance; negative regulation of actin filament polymerization; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of cellular response to growth factor stimulus; negative regulation of chemokine-mediated signaling pathway; negative regulation of endothelial cell migration; negative regulation of gene expression; negative regulation of lamellipodium assembly; negative regulation of mononuclear cell migration; negative regulation of neutrophil chemotaxis; negative regulation of protein phosphorylation; negative regulation of retinal ganglion cell axon guidance; negative regulation of small GTPase mediated signal transduction; negative regulation of smooth muscle cell chemotaxis; negative regulation of vascular permeability; olfactory bulb development; positive regulation of apoptotic process; receptor binding; response to cortisol stimulus; retinal ganglion cell axon guidance; telencephalon cell migration; ureteric bud development,PF00008;PF00054;PF13855;PF01463;PF01462;,,,,,,,,,SLIT2_MOUSE,Mus musculus (Mouse),axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; central nervous system projection neuron axonogenesis [GO:0021952]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; dorsal/ventral axon guidance [GO:0033563]; induction of negative chemotaxis [GO:0050929]; in utero embryonic development [GO:0001701]; mammary duct terminal end bud growth [GO:0060763]; mammary gland duct morphogenesis [GO:0060603]; metanephros development [GO:0001656]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of axon extension [GO:0030517]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; positive regulation of apoptotic process [GO:0043065]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; single organismal cell-cell adhesion [GO:0016337]; telencephalon cell migration [GO:0022029]; ureteric bud development [GO:0001657] comp112410_c0_seq1,532,46.6165,0.40028816,0,0,,1.00E-08,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp112410_c0_seq2,639,45.2269,0.41459141,12,0,,6.00E-76,A0JP70,WD repeat-containing protein 90,WD repeat-containing protein 90,,,PF05018;PF00400;,7.00E-73,CHOYP_LOC100371299.1.1,,,,,,,WDR90_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp112414_c0_seq1,325,41.2308,0.15290952,0,13,,8.00E-06,Q8N3J2,Methyltransferase-like protein 4 (EC 2.1.1.-),Methyltransferase-like protein 4 (EC 2.1.1.-),GO:0008168; GO:0003676; GO:0006139,methyltransferase activity; nucleic acid binding; nucleobase-containing compound metabolic process,PF05063;,,,,,,,,,METL4_HUMAN,Homo sapiens (Human), comp112414_c0_seq2,663,40.1207,0.30528805,4,35,,2.00E-10,Q3U034,Methyltransferase-like protein 4 (EC 2.1.1.-),Methyltransferase-like protein 4 (EC 2.1.1.-),GO:0008168; GO:0003676; GO:0006139,methyltransferase activity; nucleic acid binding; nucleobase-containing compound metabolic process,PF05063;,,,,,,,,,METL4_MOUSE,Mus musculus (Mouse), comp112422_c0_seq2,423,40.6619,0.2905718,0,0,,1.00E-06,Q6P4K6,Serine/threonine-protein kinase 11-interacting protein,Serine/threonine-protein kinase 11-interacting protein,GO:0005737,cytoplasm,PF15904;,,,2.00E-13,ruditapes_c31126,,,,,S11IP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp112432_c1_seq1,767,40.8083,0.5039792,15,34,,2.00E-70,O35083,1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha),1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha),GO:0003841; GO:0016024; GO:0005789; GO:0016021; GO:0006654; GO:0001819,1-acylglycerol-3-phosphate O-acyltransferase activity; CDP-diacylglycerol biosynthetic process; endoplasmic reticulum membrane; integral to membrane; phosphatidic acid biosynthetic process; positive regulation of cytokine production,PF01553;,4.00E-14,CHOYP_LOC100019982.1.1,,,,,,,PLCA_MOUSE,Mus musculus (Mouse),CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of cytokine production [GO:0001819] comp112439_c0_seq1,494,38.8664,0.7093283,5,54,,3.00E-27,Q4R4I9,PRA1 family protein 2,PRA1 family protein 2,GO:0010008; GO:0016021; GO:0015031,endosome membrane; integral to membrane; protein transport,PF03208;,4.00E-43,CHOYP_LOC100917573.1.1,,,,,,,PRAF2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein transport [GO:0015031] comp112443_c1_seq1,313,47.2843,0.45873368,8,25,,3.00E-16,Q8AV58,Protein sidekick-1,Protein sidekick-1,GO:0007155; GO:0030054; GO:0016021; GO:0005886; GO:0045202,cell adhesion; cell junction; integral to membrane; plasma membrane; synapse,PF00041;PF07679;,,,,,,,,,SDK1_CHICK,Gallus gallus (Chicken),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] comp112447_c0_seq1,963,43.7175,0.28282585,38,21,,5.00E-26,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp112463_c0_seq2,364,43.1319,0.12106227,5,16,,5.00E-10,O32220,Copper-exporting P-type ATPase A (Protein CopA) (EC 3.6.3.54) (Cu(+)-exporting ATPase),Copper-exporting P-type ATPase A (Protein CopA) (EC 3.6.3.54) (Cu(+)-exporting ATPase),GO:0005524; GO:0019829; GO:0005507; GO:0006825; GO:0016021; GO:0005886,ATP binding; cation-transporting ATPase activity; copper ion binding; copper ion transport; integral to membrane; plasma membrane,PF00122;PF00403;,,,,,,,,,COPA_BACSU,Bacillus subtilis (strain 168), comp112463_c1_seq1,456,42.1053,0.55272393,19,6,,5.00E-26,Q64535,Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Pineal night-specific ATPase) (Wilson disease-associated protein homolog),Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Pineal night-specific ATPase) (Wilson disease-associated protein homolog),GO:0005524; GO:0005794; GO:0007623; GO:0005507; GO:0004008; GO:0016021; GO:0007595; GO:0005886; GO:0051591; GO:0046688; GO:0010043; GO:0005923; GO:0005802; GO:0008270,ATP binding; Golgi apparatus; circadian rhythm; copper ion binding; copper-exporting ATPase activity; integral to membrane; lactation; plasma membrane; response to cAMP; response to copper ion; response to zinc ion; tight junction; trans-Golgi network; zinc ion binding,PF00122;PF00403;,,,,,,,,,ATP7B_RAT,Rattus norvegicus (Rat),cellular copper ion homeostasis [GO:0006878]; circadian rhythm [GO:0007623]; lactation [GO:0007595]; response to cAMP [GO:0051591]; response to copper ion [GO:0046688]; response to zinc ion [GO:0010043] comp112471_c0_seq1,999,37.6376,0.48766543,28,72,,2.00E-105,Q5ZHY5,STIP1 homology and U box-containing protein 1 (EC 6.3.2.-),STIP1 homology and U box-containing protein 1 (EC 6.3.2.-),GO:0006281; GO:0071218; GO:0005737; GO:0006515; GO:0042405; GO:0090035; GO:0032436; GO:0031398; GO:0043161; GO:0070534; GO:0051865; GO:0042803; GO:0000209; GO:0031943; GO:0000151; GO:0030579; GO:0034450,DNA repair; cellular response to misfolded protein; cytoplasm; misfolded or incompletely synthesized protein catabolic process; nuclear inclusion body; positive regulation of chaperone-mediated protein complex assembly; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination; proteasomal ubiquitin-dependent protein catabolic process; protein K63-linked ubiquitination; protein autoubiquitination; protein homodimerization activity; protein polyubiquitination; regulation of glucocorticoid metabolic process; ubiquitin ligase complex; ubiquitin-dependent SMAD protein catabolic process; ubiquitin-ubiquitin ligase activity,PF04564;,8.00E-81,CHOYP_PHUM_PHUM234540.1.1,,,,,,,CHIP_CHICK,Gallus gallus (Chicken),cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; endoplasmic reticulum unfolded protein response [GO:0030968]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; negative regulation of protein binding [GO:0032091]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of glucocorticoid metabolic process [GO:0031943]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579] comp112472_c0_seq2,728,43.8187,0.77541117,8,10,,2.00E-96,P54936,Protein lin-2 (Abnormal cell lineage protein 2),Protein lin-2 (Abnormal cell lineage protein 2),GO:0005524; GO:0030054; GO:0018991; GO:0018108; GO:0040026; GO:0009791; GO:0004713,ATP binding; cell junction; oviposition; peptidyl-tyrosine phosphorylation; positive regulation of vulval development; post-embryonic development; protein tyrosine kinase activity,PF00625;PF02828;PF00595;PF00069;PF07653;,,,,,,,,,LIN2_CAEEL,Caenorhabditis elegans,gamma-aminobutyric acid receptor clustering [GO:0097112]; oviposition [GO:0018991]; positive regulation of vulval development [GO:0040026]; post-embryonic development [GO:0009791]; protein localization to basolateral plasma membrane [GO:1903361] comp112472_c1_seq1,754,46.1538,0.50414084,43,28,,2.00E-77,O70589,Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase),Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase),GO:0005524; GO:0016323; GO:0070509; GO:0005911; GO:0005829; GO:0042043; GO:0005634; GO:0090280; GO:0045944; GO:0004674; GO:0045202,ATP binding; basolateral plasma membrane; calcium ion import; cell-cell junction; cytosol; neurexin family protein binding; nucleus; positive regulation of calcium ion import; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; synapse,PF00625;PF02828;PF00595;PF00069;PF07653;,3.00E-60,CHOYP_CSKP.2.2,,,,,,,CSKP_MOUSE,Mus musculus (Mouse),calcium ion import [GO:0070509]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; positive regulation of calcium ion import [GO:0090280]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp112489_c0_seq1,403,47.6427,0.22158978,22,28,,3.00E-52,Q4V9P0,S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26),S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26),GO:0000095; GO:0016021; GO:0005743,S-adenosyl-L-methionine transmembrane transporter activity; integral to membrane; mitochondrial inner membrane,PF00153;,5.00E-15,CHOYP_BRAFLDRAFT_72535.1.1,,,,,,,SAMC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),S-adenosyl-L-methionine transport [GO:0015805]; translation [GO:0006412] comp112496_c1_seq1,793,43.2535,0.59707505,24,35,,1.00E-98,Q8IV61,Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1),Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1),GO:0000165; GO:0046582; GO:0005088; GO:0007265; GO:0005509; GO:0019992; GO:0005085; GO:0032045; GO:0005887; GO:0048471; GO:0004871; GO:0007264,MAPK cascade; Rap GTPase activator activity; Ras guanyl-nucleotide exchange factor activity; Ras protein signal transduction; calcium ion binding; diacylglycerol binding; guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor complex; integral to plasma membrane; perinuclear region of cytoplasm; signal transducer activity; small GTPase mediated signal transduction,PF00130;PF13202;PF00617;,3.00E-110,CHOYP_LOC100889329.1.1,,,,,,,GRP3_HUMAN,Homo sapiens (Human),MAPK cascade [GO:0000165]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] comp112503_c0_seq1,338,43.787,0.31158361,12,0,,,,,,,,,7.00E-44,CHOYP_BIRC6.1.2,,,,,,,,, comp112503_c1_seq1,1295,44.0154,0.55944089,94,3,,5.00E-92,O88738,Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),GO:0005794; GO:0006915; GO:0051301; GO:0004869; GO:0005768; GO:0060711; GO:0016020; GO:0005815; GO:0030496; GO:0007067; GO:0043066; GO:0008284; GO:0032465; GO:0000922; GO:0060712; GO:0005802; GO:0004842,Golgi apparatus; apoptotic process; cell division; cysteine-type endopeptidase inhibitor activity; endosome; labyrinthine layer development; membrane; microtubule organizing center; midbody; mitosis; negative regulation of apoptotic process; positive regulation of cell proliferation; regulation of cytokinesis; spindle pole; spongiotrophoblast layer development; trans-Golgi network; ubiquitin-protein ligase activity,PF00653;PF12356;PF00179;,,,8.00E-42,ruditapes_c29078,,,,,BIRC6_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; placenta development [GO:0001890]; positive regulation of cell proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of signal transduction [GO:0009966]; spongiotrophoblast layer development [GO:0060712] comp112514_c1_seq1,225,40.8889,0.42803876,8,7,,5.00E-17,Q9QZH7,F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),GO:0005737,cytoplasm,PF12937;PF13516;,,,,,,,,,FXL20_RAT,Rattus norvegicus (Rat), comp112515_c0_seq1,730,46.0274,0.79318725,12,36,,2.00E-23,P22756,"Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)","Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)",GO:0030054; GO:0030425; GO:0008144; GO:0005234; GO:0016595; GO:0008328; GO:0015277; GO:0032229; GO:0051967; GO:0007399; GO:0043025; GO:0032230; GO:0045211; GO:0042803; GO:0048172; GO:0007268; GO:0043195; GO:0022843,"cell junction; dendrite; drug binding; extracellular-glutamate-gated ion channel activity; glutamate binding; ionotropic glutamate receptor complex; kainate selective glutamate receptor activity; negative regulation of synaptic transmission, GABAergic; negative regulation of synaptic transmission, glutamatergic; nervous system development; neuronal cell body; positive regulation of synaptic transmission, GABAergic; postsynaptic membrane; protein homodimerization activity; regulation of short-term neuronal synaptic plasticity; synaptic transmission; terminal bouton; voltage-gated cation channel activity",PF01094;PF00060;PF10613;,,,,,,,,,GRIK1_RAT,Rattus norvegicus (Rat),"chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]" comp112519_c0_seq1,556,40.4676,0.71296231,8,37,,1.00E-51,Q9VHA0,Polycomb protein Scm (Sex comb on midleg protein),Polycomb protein Scm (Sex comb on midleg protein),GO:0035102; GO:0007409; GO:0016568; GO:0016458; GO:0030708; GO:0045892; GO:0030713; GO:0005700; GO:0006351; GO:0008270,"PRC1 complex; axonogenesis; chromatin modification; gene silencing; germarium-derived female germ-line cyst encapsulation; negative regulation of transcription, DNA-dependent; ovarian follicle cell stalk formation; polytene chromosome; transcription, DNA-dependent; zinc ion binding",PF12140;PF02820;PF00536;PF06467;,,,,,,,,,SCM_DROME,Drosophila melanogaster (Fruit fly),"axonogenesis [GO:0007409]; chromatin modification [GO:0016568]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp112527_c1_seq1,437,45.3089,0.58120137,12,6,,6.00E-53,Q86UB2,Basic immunoglobulin-like variable motif-containing protein,Basic immunoglobulin-like variable motif-containing protein,GO:0005737; GO:0005634,cytoplasm; nucleus,,5.00E-22,CHOYP_BIVM.2.3,,,,,,,BIVM_HUMAN,Homo sapiens (Human), comp112531_c0_seq1,349,41.2607,0.35511655,11,14,,2.00E-16,Q6IP59,Choline transporter-like protein 2 (Solute carrier family 44 member 2),Choline transporter-like protein 2 (Solute carrier family 44 member 2),GO:0016021; GO:0006810,integral to membrane; transport,PF04515;,2.00E-12,CHOYP_CTL2.1.2,,,,,,,CTL2_XENLA,Xenopus laevis (African clawed frog),transport [GO:0006810] comp112532_c0_seq1,1685,39.7033,0.45278778,0,3,,1.00E-22,Q54PR9,Counting factor 60,Counting factor 60,GO:0005576; GO:0031158,extracellular region; negative regulation of aggregate size involved in sorocarp development,PF00328;,,,,,,,,,CF60_DICDI,Dictyostelium discoideum (Slime mold),negative regulation of aggregate size involved in sorocarp development [GO:0031158] comp112532_c0_seq2,1672,39.8325,0.4381956,2,2,,2.00E-77,Q8BP40,"Lysophosphatidic acid phosphatase type 6 (EC 3.1.3.2) (Acid phosphatase 6, lysophosphatidic) (Acid phosphatase-like protein 1) (PACPL1)","Lysophosphatidic acid phosphatase type 6 (EC 3.1.3.2) (Acid phosphatase 6, lysophosphatidic) (Acid phosphatase-like protein 1) (PACPL1)",GO:0003993; GO:0005576; GO:2001311; GO:0052642; GO:0005739,acid phosphatase activity; extracellular region; lysobisphosphatidic acid metabolic process; lysophosphatidic acid phosphatase activity; mitochondrion,PF00328;,,,,,,,,,PPA6_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244]; lysobisphosphatidic acid metabolic process [GO:2001311]; phospholipid metabolic process [GO:0006644] comp112549_c1_seq1,736,44.1576,0.92208996,23,68,,5.00E-24,Q7LL04,UPF0676 protein C1494.01,UPF0676 protein C1494.01,GO:0005829; GO:0005634; GO:0016706,"cytosol; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF03171;PF14226;,,,3.00E-13,ruditapes_c20326,,,,,YQK1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp112560_c0_seq1,332,43.6747,0.38320256,4,35,,6.00E-28,Q9UBZ4,DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2),DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2),GO:0003677; GO:0006310; GO:0006281; GO:0003906; GO:0007049; GO:0004519; GO:0004527; GO:0005743; GO:0090305; GO:0005634; GO:0008270,DNA binding; DNA recombination; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; cell cycle; endonuclease activity; exonuclease activity; mitochondrial inner membrane; nucleic acid phosphodiester bond hydrolysis; nucleus; zinc ion binding,PF03372;PF06839;,,,,,,,,,APEX2_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310] comp112564_c0_seq1,927,39.1586,0.67836336,12,172,,2.00E-10,Q6ZNG1,Zinc finger protein 600,Zinc finger protein 600,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN600_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp112573_c0_seq1,299,37.4582,0.09578651,15,117,,,,,,,,,6.00E-13,CHOYP_contig_042836,,,,,,,,, comp112578_c0_seq1,602,41.5282,0.63911146,21,19,,1.00E-41,Q9Y2G3,Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B),Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B),GO:0005524; GO:0015917; GO:0019829; GO:0005769; GO:0005783; GO:0016021; GO:0015075; GO:0000287; GO:0005637; GO:0045332; GO:0004012; GO:0005886; GO:0055037; GO:0055038,ATP binding; aminophospholipid transport; cation-transporting ATPase activity; early endosome; endoplasmic reticulum; integral to membrane; ion transmembrane transporter activity; magnesium ion binding; nuclear inner membrane; phospholipid translocation; phospholipid-translocating ATPase activity; plasma membrane; recycling endosome; recycling endosome membrane,PF00122;PF16212;PF16209;,2.00E-40,CHOYP_LOC101173537.1.1,,,,,,,AT11B_HUMAN,Homo sapiens (Human),aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332] comp112584_c0_seq1,520,42.3077,0.60326085,30,16,,2.00E-15,Q32PJ7,Tensin-4,Tensin-4,GO:0006915; GO:0005737; GO:0005856; GO:0005925,apoptotic process; cytoplasm; cytoskeleton; focal adhesion,PF08416;PF00017;,2.00E-59,CHOYP_DVIR_GJ12450.1.1,,,,,,,TENS4_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915] comp112591_c0_seq1,340,31.1765,0.72941807,1,12,,5.00E-07,Q05893,Phosphoenolpyruvate carboxykinase [GTP] (PEPCK) (EC 4.1.1.32) (Phosphoenolpyruvate carboxylase),Phosphoenolpyruvate carboxykinase [GTP] (PEPCK) (EC 4.1.1.32),GO:0005525; GO:0006094; GO:0046872; GO:0004613,GTP binding; gluconeogenesis; metal ion binding; phosphoenolpyruvate carboxykinase (GTP) activity,PF00821;,,,,,,,,,PCKG_ASCSU,Ascaris suum (Pig roundworm) (Ascaris lumbricoides),gluconeogenesis [GO:0006094] comp112618_c2_seq1,262,41.6031,0.81678209,8,21,,2.00E-10,Q6N022,Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4),Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4),GO:0060912; GO:0060038; GO:0032289; GO:0005737; GO:0001702; GO:0005887; GO:0048666; GO:0043005; GO:0005634; GO:2000543; GO:0031643; GO:0048714; GO:0042803; GO:0007165,cardiac cell fate specification; cardiac muscle cell proliferation; central nervous system myelin formation; cytoplasm; gastrulation with mouth forming second; integral to plasma membrane; neuron development; neuron projection; nucleus; positive regulation of gastrulation; positive regulation of myelination; positive regulation of oligodendrocyte differentiation; protein homodimerization activity; signal transduction,PF07974;PF06484;PF15636;,,,,,,,,,TEN4_HUMAN,Homo sapiens (Human),cardiac cell fate specification [GO:0060912]; cardiac muscle cell proliferation [GO:0060038]; central nervous system myelin formation [GO:0032289]; gastrulation with mouth forming second [GO:0001702]; neuron development [GO:0048666]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; self proteolysis [GO:0097264]; signal transduction [GO:0007165] comp112646_c0_seq1,515,65.2427,0.95528166,0,104,,2.00E-51,P00239,Ferredoxin-1 (Ferredoxin I),Ferredoxin-1 (Ferredoxin I),GO:0051537; GO:0009507; GO:0009055; GO:0022900; GO:0046872,"2 iron, 2 sulfur cluster binding; chloroplast; electron carrier activity; electron transport chain; metal ion binding",PF00111;,,,,,,,,,FER1_DUNSA,Dunaliella salina (Green alga),electron transport chain [GO:0022900] comp112654_c0_seq1,864,43.1713,0.8704727,49,216,,4.00E-10,Q9CXK4,Sugar transporter SWEET1 (MmSWEET1) (RAG1-activating protein 1) (Solute carrier family 50 member 1),Sugar transporter SWEET1 (MmSWEET1) (RAG1-activating protein 1) (Solute carrier family 50 member 1),GO:0000139; GO:0042947; GO:0016021; GO:0005634; GO:0005886; GO:0045815; GO:0051119,"Golgi membrane; glucoside transmembrane transporter activity; integral to membrane; nucleus; plasma membrane; positive regulation of gene expression, epigenetic; sugar transmembrane transporter activity",PF03083;,,,,,,,,,SWET1_MOUSE,Mus musculus (Mouse),"carbohydrate transport [GO:0008643]; positive regulation of gene expression, epigenetic [GO:0045815]" comp112667_c0_seq1,450,51.1111,1.00608189,50,190,,1.00E-10,Q3E813,Uncharacterized protein YLR154C-G,Uncharacterized protein YLR154C-G,,,,6.00E-59,CHOYP_RN45S.4.5,,,,,,,YL154_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp112669_c0_seq1,308,43.8312,0.20355946,17,0,,,,,,,,,1.00E-78,CHOYP_TTC8.1.1,,,,,,,,, comp112669_c1_seq1,410,42.1951,0.39562942,11,0,,2.00E-67,Q8TAM2,Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein),Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein),GO:0034464; GO:0007411; GO:0060219; GO:0005813; GO:0005929; GO:0042384; GO:0060170; GO:0005737; GO:0048560; GO:0045444; GO:0005932; GO:0035264; GO:0021772; GO:0032391; GO:0032880; GO:0061326; GO:0007608; GO:0050893,BBSome; axon guidance; camera-type eye photoreceptor cell differentiation; centrosome; cilium; cilium assembly; cilium membrane; cytoplasm; establishment of anatomical structure orientation; fat cell differentiation; microtubule basal body; multicellular organism growth; olfactory bulb development; photoreceptor connecting cilium; regulation of protein localization; renal tubule development; sensory perception of smell; sensory processing,PF13176;,,,7.00E-24,ruditapes_c27062,7.00E-63,CU995701.p.cg.6,7,,TTC8_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; establishment of anatomical structure orientation [GO:0048560]; protein transport [GO:0015031]; sensory processing [GO:0050893] comp112681_c0_seq1,995,42.9146,0.46313319,76,0,,4.00E-54,Q1RMK1,Protein FAM92B,Protein FAM92B,,,PF06730;,1.00E-14,CHOYP_LOC100879052.1.1,,,,,,,FA92B_BOVIN,Bos taurus (Bovine), comp112685_c1_seq1,926,46.3283,0.62876408,34,25,,1.00E-83,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,1.00E-77,CHOYP_LOC577371.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp112691_c0_seq1,326,43.5583,0.26710482,4,23,,5.00E-06,Q9GZN8,UPF0687 protein C20orf27,UPF0687 protein C20orf27,,,PF15006;,,,,,,,,,CT027_HUMAN,Homo sapiens (Human), comp112698_c0_seq1,459,41.3943,0.25624008,8,43,,4.00E-19,Q9W0E8,Protein zer-1 homolog (Zyg-11 homolog B-like protein),Protein zer-1 homolog (Zyg-11 homolog B-like protein),GO:0031462; GO:0051438; GO:0004842,Cul2-RING ubiquitin ligase complex; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,,,,,,,,,,ZER1_DROME,Drosophila melanogaster (Fruit fly),regulation of ubiquitin-protein transferase activity [GO:0051438] comp112712_c0_seq1,529,43.1002,0.50336547,11,38,,3.00E-97,Q2KHZ9,"Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6)","Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6)",GO:0050660; GO:0004361; GO:0005759; GO:0006568,flavin adenine dinucleotide binding; glutaryl-CoA dehydrogenase activity; mitochondrial matrix; tryptophan metabolic process,PF00441;PF02770;PF02771;,1.00E-99,CHOYP_LOC580832.1.1,5.00E-27,ruditapes_c9483,,,,,GCDH_BOVIN,Bos taurus (Bovine),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; tryptophan metabolic process [GO:0006568] comp112715_c0_seq1,512,37.6953,0.17665357,21,8,,2.00E-06,O88843,Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),GO:0006977; GO:0006919; GO:0071260; GO:0005737; GO:0005634; GO:2001235,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to mechanical stimulus; cytoplasm; nucleus; positive regulation of apoptotic signaling pathway",PF00619;PF00531;,,,,,,,,,CRADD_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; positive regulation of apoptotic signaling pathway [GO:2001235]" comp112724_c1_seq2,1107,46.2511,0.66017929,17,6,,2.00E-65,Q6I6G8,"E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)","E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)",GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00168;PF00632;PF16562;PF00397;,,,,,,,,,HECW2_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp112730_c2_seq1,331,41.6918,0.34866943,2,0,,2.00E-07,Q5PQ35,E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),GO:0031410; GO:0006897; GO:0005783; GO:0005789; GO:0010008; GO:0016021; GO:0005765; GO:0004842; GO:0008270,cytoplasmic vesicle; endocytosis; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; integral to membrane; lysosomal membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,MARH2_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897]; protein ubiquitination [GO:0016567] comp112730_c2_seq2,432,44.213,0.23744369,13,0,,2.00E-08,Q32L65,E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),GO:0031410; GO:0006897; GO:0005783; GO:0005789; GO:0010008; GO:0016021; GO:0005765; GO:0004842; GO:0008270,cytoplasmic vesicle; endocytosis; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; integral to membrane; lysosomal membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,MARH2_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; protein ubiquitination [GO:0016567] comp112739_c0_seq1,1071,42.8571,0.45812006,39,26,,4.00E-11,Q9CYG7,Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit),Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit),GO:0005741; GO:0005739; GO:0006626,mitochondrial outer membrane; mitochondrion; protein targeting to mitochondrion,PF00515;PF13181;,7.00E-38,CHOYP_BRAFLDRAFT_90929.1.1,,,,,,,TOM34_MOUSE,Mus musculus (Mouse),protein targeting to mitochondrion [GO:0006626] comp112754_c1_seq1,596,40.1007,0.33705105,14,11,,2.00E-54,Q9HAB8,Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase) (PPC synthetase),Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase) (PPC synthetase),GO:0015937; GO:0005829; GO:0015939; GO:0004632,coenzyme A biosynthetic process; cytosol; pantothenate metabolic process; phosphopantothenate--cysteine ligase activity,PF04127;,7.00E-28,CHOYP_BRAFLDRAFT_282135.1.1,,,,,,,PPCS_HUMAN,Homo sapiens (Human),coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108] comp112755_c0_seq1,477,38.9937,0.6150454,4,39,,3.00E-57,Q60716,"Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)","Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)",GO:0031418; GO:0005788; GO:0005506; GO:0016702; GO:0018401; GO:0004656,"L-ascorbic acid binding; endoplasmic reticulum lumen; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; procollagen-proline 4-dioxygenase activity",PF13640;PF08336;,3.00E-26,CHOYP_PHUM_PHUM445570.1.1,,,,,,,P4HA2_MOUSE,Mus musculus (Mouse),peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] comp112773_c0_seq1,290,42.4138,0.33162787,1,9,,5.00E-22,Q6AXB1,UPF0364 protein C6orf211 homolog,Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1),,,PF01937;,,,,,,,,,CF211_XENLA,Xenopus laevis (African clawed frog),methylation [GO:0032259]; regulation of response to DNA damage stimulus [GO:2001020] comp112785_c0_seq1,234,63.2479,1.07602698,0,21,,2.00E-26,P16100,Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),GO:0005737; GO:0006097; GO:0004450; GO:0046872; GO:0006099,cytoplasm; glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; metal ion binding; tricarboxylic acid cycle,PF03971;,,,,,,,,,IDH_AZOVI,Azotobacter vinelandii,glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] comp112785_c1_seq1,214,64.486,1.13279607,0,4,,5.00E-21,Q8RQL9,Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),GO:0006097; GO:0004450; GO:0046872; GO:0006099,glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; metal ion binding; tricarboxylic acid cycle,PF03971;,,,,,,,,,IDH_COREF,Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395),glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] comp112790_c0_seq1,430,40.2326,0.17649563,9,30,,2.00E-31,Q05858,Formin (Limb deformity protein),Formin (Limb deformity protein),GO:0005884; GO:0045010; GO:0007275; GO:0005634,actin filament; actin nucleation; multicellular organismal development; nucleus,PF02181;,,,,,,,,,FMN_CHICK,Gallus gallus (Chicken),actin nucleation [GO:0045010]; multicellular organism development [GO:0007275] comp112791_c0_seq1,497,38.4306,0.67540961,16,24,,2.00E-11,A5GZY1,Neuromacin-like protein,Neuromacin-like protein,GO:0005576,extracellular region,PF14865;,,,,,,,,,NEURM_APLCA,Aplysia californica (California sea hare),defense response [GO:0006952] comp112818_c1_seq1,378,42.8571,0.46467758,10,25,,3.00E-17,P97402,"N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase)","N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase)",GO:0000139; GO:0008109; GO:0008375; GO:0016021; GO:0006486,"Golgi membrane; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity; integral to membrane; protein glycosylation",PF02485;,,,,,,,,,GCNT2_MOUSE,Mus musculus (Mouse),maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; posttranscriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp112823_c1_seq1,1034,44.4874,0.58705695,0,0,,1.00E-50,Q8NEM8,Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3),Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3),GO:0005829; GO:0004181; GO:0006508; GO:0008270,cytosol; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,,,,,,,,,CBPC3_HUMAN,Homo sapiens (Human),protein side chain deglutamylation [GO:0035610] comp112823_c1_seq2,1113,45.0135,0.58586775,9,3,,0,Q09LZ8,Cytosolic carboxypeptidase 6 (EC 3.4.17.-) (ATP/GTP-binding protein-like 4),Cytosolic carboxypeptidase 6 (EC 3.4.17.-) (ATP/GTP-binding protein-like 4),GO:0035609; GO:0005829; GO:0004181; GO:0035610; GO:0006508; GO:0015631; GO:0008270,C-terminal protein deglutamylation; cytosol; metallocarboxypeptidase activity; protein side chain deglutamylation; proteolysis; tubulin binding; zinc ion binding,PF00246;,0,CHOYP_LOC100375368.1.1,,,,,,,CBPC6_MOUSE,Mus musculus (Mouse),C-terminal protein deglutamylation [GO:0035609]; defense response to virus [GO:0051607]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610] comp112828_c0_seq1,563,47.2469,0.80163992,0,0,,4.00E-34,Q8NCJ5,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,,,,,,,,,SPRY3_HUMAN,Homo sapiens (Human), comp112828_c0_seq2,970,46.5979,0.86035888,18,33,,7.00E-72,Q8NCJ5,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,2.00E-11,CHOYP_SPRY3.1.1,,,,,,,SPRY3_HUMAN,Homo sapiens (Human), comp112829_c0_seq1,251,74.9004,0.94159103,0,15,,4.00E-11,Q05627,Uncharacterized protein Cbei_0202 (ORF1),Uncharacterized protein Cbei_0202 (ORF1),,,,,,,,,,,,Y202_CLOB8,Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum), comp112830_c0_seq1,492,32.9268,0.76827495,20,16,,9.00E-26,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,3.00E-26,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp112832_c0_seq1,251,42.6295,0.71187571,0,18,,3.00E-16,Q54V86,ABC transporter C family member 13 (ABC transporter ABCC.13),ABC transporter C family member 13 (ABC transporter ABCC.13),GO:0005524; GO:0042626; GO:0031154; GO:0016021; GO:0031288,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; culmination involved in sorocarp development; integral to membrane; sorocarp morphogenesis",PF00664;PF00005;,1.00E-20,CHOYP_BRAFLDRAFT_118957.1.1,,,,,,,ABCCD_DICDI,Dictyostelium discoideum (Slime mold),culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810] comp112832_c0_seq2,217,40.553,0.33851651,0,6,,9.00E-12,Q7GB25,ABC transporter C family member 5 (ABC transporter ABCC.5) (AtABCC5) (EC 3.6.3.44) (ATP-energized glutathione S-conjugate pump 5) (Glutathione S-conjugate-transporting ATPase 5) (Multidrug resistance-associated protein 5),ABC transporter C family member 5 (ABC transporter ABCC.5) (AtABCC5) (EC 3.6.3.44) (ATP-energized glutathione S-conjugate pump 5) (Glutathione S-conjugate-transporting ATPase 5) (Multidrug resistance-associated protein 5),GO:0005524; GO:0042626; GO:0030007; GO:0016021; GO:0000325; GO:0009651; GO:0008281; GO:0005774; GO:0008559,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cellular potassium ion homeostasis; integral to membrane; plant-type vacuole; response to salt stress; sulfonylurea receptor activity; vacuolar membrane; xenobiotic-transporting ATPase activity",PF00664;PF00005;,,,,,,,,,AB5C_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid-activated signaling pathway involved in stomatal movement [GO:1901527]; cellular potassium ion homeostasis [GO:0030007]; response to salt stress [GO:0009651] comp112832_c1_seq2,297,39.3939,0.43618761,4,20,,1.00E-24,Q63120,Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2),Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2),GO:0005524; GO:0006200; GO:0042626; GO:0016324; GO:0030644; GO:0006855; GO:0005887; GO:0046581; GO:0008514; GO:0015732; GO:0046685; GO:0043627; GO:0009408; GO:0031427; GO:0006979; GO:0070327,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; apical plasma membrane; cellular chloride ion homeostasis; drug transmembrane transport; integral to plasma membrane; intercellular canaliculus; organic anion transmembrane transporter activity; prostaglandin transport; response to arsenic-containing substance; response to estrogen stimulus; response to heat; response to methotrexate; response to oxidative stress; thyroid hormone transport",PF00664;PF00005;,6.00E-13,CHOYP_BRAFLDRAFT_118957.1.1,,,,,,,MRP2_RAT,Rattus norvegicus (Rat),antibiotic metabolic process [GO:0016999]; benzylpenicillin metabolic process [GO:1901086]; canalicular bile acid transport [GO:0015722]; cellular chloride ion homeostasis [GO:0030644]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; drug transmembrane transport [GO:0006855]; female pregnancy [GO:0007565]; mercury ion transport [GO:0015694]; organic anion transport [GO:0015711]; prostaglandin transport [GO:0015732]; response to antineoplastic agent [GO:0097327]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; thyroid hormone transport [GO:0070327] comp112840_c1_seq3,1214,48.2702,0.4293896,25,24,,1.00E-69,Q69ZU6,Thrombospondin type-1 domain-containing protein 7A,Thrombospondin type-1 domain-containing protein 7A,GO:0001525; GO:0030154; GO:0005576; GO:0016021; GO:0005886,angiogenesis; cell differentiation; extracellular region; integral to membrane; plasma membrane,PF00090;,,,,,,,,,THS7A_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell differentiation [GO:0030154] comp112845_c0_seq1,356,33.1461,0.42500335,12,7,,8.00E-08,O94911,ATP-binding cassette sub-family A member 8,ATP-binding cassette sub-family A member 8,GO:0005524; GO:0006200; GO:0016887; GO:0042626; GO:0016021; GO:0005743; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrial inner membrane; plasma membrane",PF00005;,,,,,,,,,ABCA8_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp112867_c0_seq1,359,47.3538,0.4000031,10,0,,2.00E-26,Q0KK59,Protein unc-79 homolog,Protein unc-79 homolog,GO:0048149; GO:0016021; GO:0035264,behavioral response to ethanol; integral to membrane; multicellular organism growth,,3.00E-55,CHOYP_LOC100374509.1.1,,,,,,,UNC79_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] comp112868_c0_seq1,300,45.6667,0.57737214,2,26,,1.00E-12,A2RRP1,Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein),Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein),GO:0005737,cytoplasm,PF15492;PF08314;,,,,,,,,,NBAS_HUMAN,Homo sapiens (Human),"negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp112889_c0_seq1,494,42.915,0.49590367,3,54,,9.00E-33,Q5U247,Exocyst complex component 8,Exocyst complex component 8,GO:0005737; GO:0006887; GO:0005543; GO:0015031,cytoplasm; exocytosis; phospholipid binding; protein transport,PF16528;,7.00E-59,CHOYP_LOC100699161.1.1,,,,,,,EXOC8_XENLA,Xenopus laevis (African clawed frog),exocytosis [GO:0006887]; protein transport [GO:0015031] comp112891_c2_seq1,519,44.1233,0.40222922,11,20,,4.00E-39,Q04448,"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (DNMDMC) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]","Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (DNMDMC) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]",GO:0009396; GO:0000287; GO:0004477; GO:0004487; GO:0004488; GO:0005739; GO:0006730; GO:0042301; GO:0046653,folic acid-containing compound biosynthetic process; magnesium ion binding; methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; methylenetetrahydrofolate dehydrogenase (NADP+) activity; mitochondrion; one-carbon metabolic process; phosphate ion binding; tetrahydrofolate metabolic process,PF00763;PF02882;,1.00E-74,CHOYP_LOC100164363.1.1,,,,,,,MTDC_DROME,Drosophila melanogaster (Fruit fly),10-formyltetrahydrofolate metabolic process [GO:0009256]; carbohydrate metabolic process [GO:0005975]; folic acid-containing compound biosynthetic process [GO:0009396]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate metabolic process [GO:0046653] comp112895_c0_seq1,248,66.5323,1.10668466,0,28,,6.00E-42,Q16CP0,1-deoxy-D-xylulose-5-phosphate synthase 2 (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase 2) (DXP synthase 2) (DXPS 2),1-deoxy-D-xylulose-5-phosphate synthase 2 (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase 2) (DXP synthase 2) (DXPS 2),GO:0052865; GO:0008661; GO:0000287; GO:0016114; GO:0009228; GO:0030976,1-deoxy-D-xylulose 5-phosphate biosynthetic process; 1-deoxy-D-xylulose-5-phosphate synthase activity; magnesium ion binding; terpenoid biosynthetic process; thiamine biosynthetic process; thiamine pyrophosphate binding,PF13292;PF02779;PF02780;,,,,,,,,,DXS2_ROSDO,Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans),1-deoxy-D-xylulose 5-phosphate biosynthetic process [GO:0052865]; terpenoid biosynthetic process [GO:0016114]; thiamine biosynthetic process [GO:0009228] comp112914_c0_seq2,787,43.5832,0.61772424,11,29,,3.00E-67,P55214,"Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11; Caspase-7, N-terminally processed]",Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11],GO:0006915; GO:0004197; GO:0005737; GO:0006508,apoptotic process; cysteine-type endopeptidase activity; cytoplasm; proteolysis,,,,,,,,,,CASP7_MESAU,Mesocricetus auratus (Golden hamster),apoptotic process [GO:0006915] comp112916_c0_seq1,920,45.2174,0.59655849,11,167,,7.00E-31,Q63356,Unconventional myosin-Ie (Myosin heavy chain myr 3) (Unconventional myosin 1E),Unconventional myosin-Ie (Myosin heavy chain myr 3) (Unconventional myosin 1E),GO:0005524; GO:0042623; GO:0051015; GO:0005912; GO:0005516; GO:0005911; GO:0030136; GO:0005737; GO:0005856; GO:0006897; GO:0032836; GO:0003094; GO:0072015; GO:0003774; GO:0016459; GO:0035091; GO:0043234,"ATP binding; ATPase activity, coupled; actin filament binding; adherens junction; calmodulin binding; cell-cell junction; clathrin-coated vesicle; cytoplasm; cytoskeleton; endocytosis; glomerular basement membrane development; glomerular filtration; glomerular visceral epithelial cell development; motor activity; myosin complex; phosphatidylinositol binding; protein complex",PF00063;PF06017;PF00018;,,,,,,,,,MYO1E_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015] comp112916_c0_seq2,589,40.0679,0.51293345,0,1,,6.00E-14,P19706,Myosin heavy chain IB (Myosin heavy chain IL),Myosin heavy chain IB (Myosin heavy chain IL),GO:0005524; GO:0003774; GO:0016459,ATP binding; motor activity; myosin complex,PF00063;PF06017;PF00018;,6.00E-29,CHOYP_MYO1E.1.1,,,,,,,MYSB_ACACA,Acanthamoeba castellanii (Amoeba), comp112918_c0_seq1,454,44.7137,0.31085452,18,49,,8.00E-41,Q96T66,Nicotinamide mononucleotide adenylyltransferase 3 (NMN adenylyltransferase 3) (Nicotinate-nucleotide adenylyltransferase 3) (NaMN adenylyltransferase 3) (EC 2.7.7.18) (Pyridine nucleotide adenylyltransferase 3) (PNAT-3) (EC 2.7.7.1),Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3) (Nicotinamide-nucleotide adenylyltransferase 3) (NMN adenylyltransferase 3) (Nicotinate-nucleotide adenylyltransferase 3) (NaMN adenylyltransferase 3) (EC 2.7.7.18) (Pyridine nucleotide adenylyltransferase 3) (PNAT-3) (EC 2.7.7.1),GO:0005524; GO:0009435; GO:0005829; GO:0005739; GO:0000309; GO:0004515; GO:0009611; GO:0006767,ATP binding; NAD biosynthetic process; cytosol; mitochondrion; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; response to wounding; water-soluble vitamin metabolic process,PF01467;,,,5.00E-58,ruditapes_c8300,,,,,NMNA3_HUMAN,Homo sapiens (Human),'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD metabolic process [GO:0019674]; response to wounding [GO:0009611] comp112918_c1_seq1,426,42.0188,0.6569267,20,24,,8.00E-45,Q9HAN9,Nicotinamide mononucleotide adenylyltransferase 1 (NMN adenylyltransferase 1) (EC 2.7.7.1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) (EC 2.7.7.18),Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1),GO:0005524; GO:0009435; GO:0000309; GO:0004515; GO:0005654; GO:0006767,ATP binding; NAD biosynthetic process; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; nucleoplasm; water-soluble vitamin metabolic process,PF01467;,1.00E-48,CHOYP_LOC577778.1.1,,,,,,,NMNA1_HUMAN,Homo sapiens (Human),'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD metabolic process [GO:0019674]; response to wounding [GO:0009611] comp112954_c0_seq1,779,39.4095,0.51560106,31,102,,4.00E-48,Q8MQJ9,Brain tumor protein,Brain tumor protein,GO:0008356; GO:0055060; GO:0007411; GO:0007420; GO:0005737; GO:0007402; GO:0007406; GO:0048477; GO:0006909; GO:0009303; GO:0035282; GO:0030371; GO:0008270,asymmetric cell division; asymmetric neuroblast division resulting in ganglion mother cell formation; axon guidance; brain development; cytoplasm; ganglion mother cell fate determination; negative regulation of neuroblast proliferation; oogenesis; phagocytosis; rRNA transcription; segmentation; translation repressor activity; zinc ion binding,PF01436;PF00643;,7.00E-68,CHOYP_LOC100902046.1.1,,,,,,,BRAT_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419] comp112963_c0_seq1,317,42.5868,0.14021304,3,22,,,,,,,,,3.00E-11,CHOYP_BRAFLDRAFT_85147.1.1,,,,,,,,, comp112966_c0_seq1,330,50.9091,1.0343845,16,156,,2.00E-52,Q9H853,Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B),Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B),GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0005200,GTP binding; cytoplasm; microtubule; microtubule-based process; structural constituent of cytoskeleton,PF00091;,3.00E-67,CHOYP_LOC754102.1.1,,,,,,,TBA4B_HUMAN,Homo sapiens (Human),microtubule-based process [GO:0007017] comp112966_c1_seq1,269,52.0446,1.26736445,0,70,,4.00E-51,P33628,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0005200,GTP binding; cytoplasm; microtubule; microtubule-based process; structural constituent of cytoskeleton,PF00091;,5.00E-57,CHOYP_TBB.5.7,1.00E-50,ruditapes_c25365,,,,,TBA_PICAB,Picea abies (Norway spruce) (Picea excelsa),microtubule-based process [GO:0007017] comp112966_c2_seq1,400,48.75,1.26402964,35,332,,2.00E-88,P02552,Tubulin alpha-1 chain (Fragment),Tubulin alpha-1 chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,3.00E-100,CHOYP_TBA1A.1.4,1.00E-97,ruditapes2_lrc3145,,,,,TBA1_CHICK,Gallus gallus (Chicken),microtubule-based process [GO:0007017] comp112972_c0_seq1,761,45.0723,0.57352135,0,0,,1.00E-33,Q5SUV5,Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085),Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,MYLK4_MOUSE,Mus musculus (Mouse), comp112973_c1_seq1,293,46.7577,0.31531899,7,20,,,,,,,,,2.00E-11,CHOYP_LOC100014225.1.1,,,,,,,,, comp112979_c0_seq1,228,62.2807,1.16364027,5,4,,1.00E-43,Q6A763,DNA polymerase IV (Pol IV) (EC 2.7.7.7),DNA polymerase IV (Pol IV) (EC 2.7.7.7),GO:0006281; GO:0006261; GO:0003887; GO:0005737; GO:0003684; GO:0000287,DNA repair; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; cytoplasm; damaged DNA binding; magnesium ion binding,PF00817;PF11799;,,,,,,,,,DPO4_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281] comp112981_c1_seq1,468,38.4615,0.23916478,16,18,,1.00E-23,Q3U2J5,Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60),Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60),GO:0005794; GO:0018025; GO:0005634,Golgi apparatus; calmodulin-lysine N-methyltransferase activity; nucleus,PF10294;,,,,,,,,,CMKMT_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; peptidyl-lysine methylation [GO:0018022] comp112985_c0_seq1,335,37.3134,0.259395,0,0,,2.00E-12,Q52KR2,Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2),Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2),GO:0005737; GO:0016021; GO:0005886,cytoplasm; integral to membrane; plasma membrane,PF07679;PF13855;PF01463;,,,,,,,,,LRIG2_MOUSE,Mus musculus (Mouse),innervation [GO:0060384]; regulation of platelet-derived growth factor receptor signaling pathway [GO:0010640]; sensory perception of sound [GO:0007605] comp112985_c0_seq2,685,39.4161,0.67786706,9,20,,4.00E-24,O75093,Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4),Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4),GO:0048846; GO:0005509; GO:0005737; GO:0033563; GO:0040023; GO:0005615; GO:0048853; GO:0008045; GO:0050919; GO:0048843; GO:0051964; GO:0031290; GO:0021510; GO:0022028,axon extension involved in axon guidance; calcium ion binding; cytoplasm; dorsal/ventral axon guidance; establishment of nucleus localization; extracellular space; forebrain morphogenesis; motor neuron axon guidance; negative chemotaxis; negative regulation of axon extension involved in axon guidance; negative regulation of synapse assembly; retinal ganglion cell axon guidance; spinal cord development; tangential migration from the subventricular zone to the olfactory bulb,PF00008;PF12661;PF00054;PF13855;PF01463;PF01462;,,,,,,,,,SLIT1_HUMAN,Homo sapiens (Human),axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; dorsal/ventral axon guidance [GO:0033563]; establishment of nucleus localization [GO:0040023]; forebrain morphogenesis [GO:0048853]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of synapse assembly [GO:0051964]; regulation of axonogenesis [GO:0050770]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028] comp113008_c0_seq1,788,35.533,0.72995595,20,34,,2.00E-15,Q7TS63,Zinc finger protein ZFAT (Zinc finger protein 406),Zinc finger protein ZFAT (Zinc finger protein 406),GO:0003677; GO:0001077; GO:0005829; GO:0002244; GO:0046872; GO:0005634; GO:0060712,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cytosol; hematopoietic progenitor cell differentiation; metal ion binding; nucleus; spongiotrophoblast layer development,,,,,,,,,,ZFAT_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244]; hemopoiesis [GO:0030097]; spongiotrophoblast layer development [GO:0060712] comp113008_c1_seq1,571,42.3818,0.59645647,19,12,,1.00E-34,Q9NSD4,Zinc finger protein 275,Zinc finger protein 275,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN275_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp113009_c0_seq1,292,46.9178,0.44568102,4,20,,6.00E-14,Q9CR22,Transmembrane protein 42,Transmembrane protein 42,GO:0016021,integral to membrane,,,,,,,,,,TMM42_MOUSE,Mus musculus (Mouse), comp113012_c0_seq2,423,44.208,0.84206078,8,3,,4.00E-24,P30122,Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),GO:0047372; GO:0004091; GO:0005829; GO:0005615; GO:0016042; GO:0004771; GO:0004806,acylglycerol lipase activity; carboxylesterase activity; cytosol; extracellular space; lipid catabolic process; sterol esterase activity; triglyceride lipase activity,PF00135;,,,,,,,,,CEL_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp113024_c0_seq2,544,36.7647,0.2190742,14,5,,7.00E-10,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp113035_c0_seq1,355,38.0282,0.88079871,8,19,,1.00E-11,Q17RP2,Tigger transposable element-derived protein 6,Tigger transposable element-derived protein 6,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD6_HUMAN,Homo sapiens (Human), comp113035_c1_seq1,401,41.1471,0.59170224,23,28,,6.00E-15,Q4W5G0,Tigger transposable element-derived protein 2,Tigger transposable element-derived protein 2,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD2_HUMAN,Homo sapiens (Human), comp113036_c0_seq1,444,44.3694,0.87963409,2,108,,5.00E-15,Q6B9X6,Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),GO:0005524; GO:0005516; GO:0031164; GO:0000331; GO:0005829; GO:0000281; GO:0031038; GO:0018209; GO:0018107; GO:0048471; GO:0004674; GO:0031156; GO:0031288,ATP binding; calmodulin binding; contractile vacuolar membrane; contractile vacuole; cytosol; mitotic cytokinesis; myosin II filament organization; peptidyl-serine modification; peptidyl-threonine phosphorylation; perinuclear region of cytoplasm; protein serine/threonine kinase activity; regulation of sorocarp development; sorocarp morphogenesis,PF02816;,,,3.00E-23,ruditapes_c7830,,,,,VWKA_DICDI,Dictyostelium discoideum (Slime mold),contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288] comp113043_c1_seq1,416,43.2692,0.41190508,12,7,,3.00E-20,Q6P3V2,Zinc finger protein 585A,Zinc finger protein 585A,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,Z585A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp113043_c2_seq1,548,48.3577,0.59558266,23,11,,8.00E-18,Q92010,Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 5) (ZF5),Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 5) (ZF5),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,7.00E-28,CHOYP_LOC100558121.1.1,,,,,,,ZF161_CHICK,Gallus gallus (Chicken),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp113045_c0_seq1,240,42.5,0.10759115,7,16,,5.00E-06,Q5ZKG3,DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],GO:0051539; GO:0043139; GO:0017108; GO:0005524; GO:0003677; GO:0000729; GO:0000076; GO:0043137; GO:0006284; GO:0046872; GO:0006264; GO:0005739; GO:0005634; GO:0045740; GO:0043142; GO:0016890,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; 5'-flap endonuclease activity; ATP binding; DNA binding; DNA double-strand break processing; DNA replication checkpoint; DNA replication, removal of RNA primer; base-excision repair; metal ion binding; mitochondrial DNA replication; mitochondrion; nucleus; positive regulation of DNA replication; single-stranded DNA-dependent ATPase activity; site-specific endodeoxyribonuclease activity, specific for altered base",PF08696;,2.00E-31,CHOYP_BRAFLDRAFT_215302.1.1,,,,,,,DNA2_CHICK,Gallus gallus (Chicken),"base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; DNA replication checkpoint [GO:0000076]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740]" comp113045_c1_seq1,365,46.0274,0.36731459,15,9,,2.00E-21,Q6J5K9,Probable RNA helicase armi (EC 3.6.4.13) (Protein armitage),Probable RNA helicase armi (EC 3.6.4.13) (Protein armitage),GO:0005524; GO:0003678; GO:0016246; GO:0070725; GO:0030424; GO:0005737; GO:0030425; GO:0046843; GO:0007616; GO:0031023; GO:0043025; GO:0000184; GO:0007318; GO:0045202,"ATP binding; DNA helicase activity; RNA interference; Yb body; axon; cytoplasm; dendrite; dorsal appendage formation; long-term memory; microtubule organizing center organization; neuronal cell body; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; pole plasm protein localization; synapse",,,,,,,,,,ARMI_DROME,Drosophila melanogaster (Fruit fly),"dorsal appendage formation [GO:0046843]; embryonic axis specification [GO:0000578]; germarium-derived egg chamber formation [GO:0007293]; long-term memory [GO:0007616]; microtubule organizing center organization [GO:0031023]; negative regulation of DNA damage checkpoint [GO:2000002]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oogenesis [GO:0048477]; pole plasm protein localization [GO:0007318]; RNA interference [GO:0016246]" comp113045_c2_seq1,373,44.7721,0.32922772,4,22,,7.00E-44,Q99MV5,Putative helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1),RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog),GO:0005524; GO:0008283; GO:0005737; GO:0004386; GO:0007517; GO:0045786; GO:0007283,ATP binding; cell proliferation; cytoplasm; helicase activity; muscle organ development; negative regulation of cell cycle; spermatogenesis,,,,,,,,,,M10L1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp113046_c0_seq1,266,62.406,1.12545195,0,0,,8.00E-55,Q6A6C0,Phosphoribosylformylglycinamidine synthase 2 (EC 6.3.5.3) (Phosphoribosylformylglycinamidine synthase II) (FGAM synthase II),Phosphoribosylformylglycinamidine synthase subunit PurL (FGAM synthase) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase subunit II) (FGAR amidotransferase II) (FGAR-AT II) (Glutamine amidotransferase PurL) (Phosphoribosylformylglycinamidine synthase subunit II),GO:0006189; GO:0005524; GO:0005737; GO:0004642,'de novo' IMP biosynthetic process; ATP binding; cytoplasm; phosphoribosylformylglycinamidine synthase activity,PF00586;PF02769;,,,,,,,,,PURL_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' IMP biosynthetic process [GO:0006189] comp113050_c0_seq1,497,36.2173,0.24620048,25,2,,,,,,,,,,,2.00E-13,ruditapes_c4344,,,,,,, comp113051_c0_seq1,479,47.8079,0.32952089,24,12,,1.00E-17,Q5ZLR6,Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6),Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6),GO:0005089; GO:0005737; GO:0035556; GO:0030027; GO:0030032; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cytoplasm; intracellular signal transduction; lamellipodium; lamellipodium assembly; phospholipid binding; regulation of Rho protein signal transduction,PF16523;PF00307;PF00169;PF00621;PF14604;,1.00E-30,CHOYP_ARHG7.3.5,,,,,,,ARHG6_CHICK,Gallus gallus (Chicken),intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023] comp113055_c0_seq1,1203,45.3034,0.50640434,34,97,,5.00E-36,Q9UJU6,Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7),Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7),GO:0000139; GO:0016601; GO:0051015; GO:0007257; GO:0005938; GO:0030054; GO:0006921; GO:0030665; GO:0005829; GO:0030425; GO:0006897; GO:0008047; GO:0030027; GO:0048812; GO:0005886; GO:0002102; GO:0071800; GO:0014069; GO:0001726; GO:0007416,Golgi membrane; Rac protein signal transduction; actin filament binding; activation of JUN kinase activity; cell cortex; cell junction; cellular component disassembly involved in execution phase of apoptosis; clathrin-coated vesicle membrane; cytosol; dendrite; endocytosis; enzyme activator activity; lamellipodium; neuron projection morphogenesis; plasma membrane; podosome; podosome assembly; postsynaptic density; ruffle; synapse assembly,PF00241;PF14604;,,,,,,,,,DBNL_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; receptor-mediated endocytosis [GO:0006898]; ruffle assembly [GO:0097178]; synapse assembly [GO:0007416] comp113055_c0_seq2,666,40.2402,0.26427863,0,0,,4.00E-11,P15891,Actin-binding protein,Actin-binding protein,GO:0030479; GO:0000147; GO:0051015; GO:0008104,actin cortical patch; actin cortical patch assembly; actin filament binding; protein localization,PF00241;PF00018;,3.00E-27,CHOYP_LOC100374625.1.1,,,,,,,ABP1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; protein localization [GO:0008104] comp113064_c0_seq1,258,46.124,0.80526931,5,0,,2.00E-25,P82251,"B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)","b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)",GO:0015184; GO:0007596; GO:0006520; GO:0005887; GO:0050900; GO:0015175; GO:0042605; GO:0006461,L-cystine transmembrane transporter activity; blood coagulation; cellular amino acid metabolic process; integral to plasma membrane; leukocyte migration; neutral amino acid transmembrane transporter activity; peptide antigen binding; protein complex assembly,PF13520;,7.00E-24,CHOYP_BAT1.1.4,,,,,,,BAT1_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; leukocyte migration [GO:0050900]; neutral amino acid transport [GO:0015804]; protein complex assembly [GO:0006461] comp113070_c0_seq1,240,37.5,0.12050209,6,14,,2.00E-13,Q32KL4,Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B),Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B),GO:0005737; GO:0005874; GO:0000922,cytoplasm; microtubule; spindle pole,,3.00E-27,CHOYP_BRAFLDRAFT_120481.1.1,,,,,,,RMD1_BOVIN,Bos taurus (Bovine), comp113070_c1_seq1,387,42.1189,0.36546555,10,13,,1.00E-23,Q0P4W3,Regulator of microtubule dynamics protein 2 (RMD-2) (Protein FAM82A1),Regulator of microtubule dynamics protein 2 (RMD-2) (Protein FAM82A1),GO:0016021,integral to membrane,,,,,,,,,,RMD2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp113078_c0_seq1,736,43.4783,0.28817257,29,9,,7.00E-49,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,,,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp113091_c1_seq1,279,39.7849,0.78049783,9,17,,1.00E-18,Q9CXF4,TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),GO:0005097; GO:0005576; GO:0005739,Rab GTPase activator activity; extracellular region; mitochondrion,PF12068;PF00566;,1.00E-20,CHOYP_LOC100374734.1.1,,,,,,,TBC15_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338] comp113097_c2_seq1,349,41.8338,0.26590912,6,31,,2.00E-39,B2RYH9,Hippocampus abundant transcript-like protein 1,Hippocampus abundant transcript-like protein 1 (Major facilitator superfamily domain-containing 14B),GO:0016021; GO:0005886; GO:0055085; GO:0005215,integral to membrane; plasma membrane; transmembrane transport; transporter activity,PF07690;,8.00E-31,CHOYP_HIAT1.1.1,,,,,,,HIAL1_RAT,Rattus norvegicus (Rat),transmembrane transport [GO:0055085] comp113098_c2_seq1,906,39.8455,0.76461315,71,34,,2.00E-92,P52824,Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta),Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta),GO:0005524; GO:0003951; GO:0019933; GO:0005856; GO:0005829; GO:0004143; GO:0046872; GO:0016607; GO:0005886; GO:0030168; GO:0070528; GO:0007205; GO:0033198; GO:0070493,ATP binding; NAD+ kinase activity; cAMP-mediated signaling; cytoskeleton; cytosol; diacylglycerol kinase activity; metal ion binding; nuclear speck; plasma membrane; platelet activation; protein kinase C signaling cascade; protein kinase C-activating G-protein coupled receptor signaling pathway; response to ATP; thrombin receptor signaling pathway,PF00130;PF00609;PF00781;PF00788;,2.00E-101,CHOYP_LOC100900935.1.1,,,,,,,DGKQ_HUMAN,Homo sapiens (Human),cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ATP [GO:0033198]; thrombin receptor signaling pathway [GO:0070493] comp113099_c1_seq1,662,45.7704,0.73562213,1,124,,,,,,,,,,,2.00E-14,ruditapes_c10211,,,,,,, comp113100_c0_seq1,204,48.0392,0.43140767,0,25,,6.00E-06,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp113107_c0_seq1,949,40.8851,0.48836634,55,98,,7.00E-55,Q91YT2,E3 ubiquitin-protein ligase RNF185 (EC 6.3.2.-) (RING finger protein 185),E3 ubiquitin-protein ligase RNF185 (EC 6.3.2.-) (RING finger protein 185),GO:0006914; GO:0016021; GO:0016874; GO:0005741; GO:0016567; GO:0008270,autophagy; integral to membrane; ligase activity; mitochondrial outer membrane; protein ubiquitination; zinc ion binding,,5.00E-70,CHOYP_RN185.2.2,,,,,,,RN185_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein autoubiquitination [GO:0051865] comp113123_c0_seq1,368,48.0978,0.47551898,17,18,,4.00E-28,Q5VV63,Attractin-like protein 1,Attractin-like protein 1,GO:0007186; GO:0030246; GO:0016021; GO:0007275; GO:0004872,G-protein coupled receptor signaling pathway; carbohydrate binding; integral to membrane; multicellular organismal development; receptor activity,PF00431;PF07974;PF01344;PF00059;PF01437;,2.00E-32,CHOYP_LOC100871946.1.1,,,,,,,ATRN1_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186] comp113125_c0_seq1,394,42.132,0.46037593,5,17,,8.00E-06,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp113126_c0_seq1,481,41.7879,0.38337807,30,45,,1.00E-52,Q99J82,Integrin-linked protein kinase (EC 2.7.11.1),Integrin-linked protein kinase (EC 2.7.11.1),GO:0005524; GO:0017124; GO:0007569; GO:0007050; GO:0005911; GO:0043034; GO:0043198; GO:0043206; GO:0005925; GO:0007229; GO:0030027; GO:0032288; GO:0010667; GO:0043524; GO:0006469; GO:0014912; GO:0048662; GO:0048812; GO:0043025; GO:0018105; GO:0005886; GO:0030513; GO:0043406; GO:0045773; GO:0090263; GO:0030335; GO:0008284; GO:0001954; GO:0050775; GO:0045663; GO:0045669; GO:0051897; GO:0045893; GO:0043234; GO:0051291; GO:0004674; GO:0032956; GO:0030017; GO:0004871; GO:0034446; GO:0043195,"ATP binding; SH3 domain binding; cell aging; cell cycle arrest; cell-cell junction; costamere; dendritic shaft; extracellular fibril organization; focal adhesion; integrin-mediated signaling pathway; lamellipodium; myelin assembly; negative regulation of cardiac muscle cell apoptotic process; negative regulation of neuron apoptotic process; negative regulation of protein kinase activity; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; neuron projection morphogenesis; neuronal cell body; peptidyl-serine phosphorylation; plasma membrane; positive regulation of BMP signaling pathway; positive regulation of MAP kinase activity; positive regulation of axon extension; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of cell-matrix adhesion; positive regulation of dendrite morphogenesis; positive regulation of myoblast differentiation; positive regulation of osteoblast differentiation; positive regulation of protein kinase B signaling cascade; positive regulation of transcription, DNA-dependent; protein complex; protein heterooligomerization; protein serine/threonine kinase activity; regulation of actin cytoskeleton organization; sarcomere; signal transducer activity; substrate adhesion-dependent cell spreading; terminal bouton",PF12796;PF07714;,3.00E-51,CHOYP_ISCW_ISCW017519.1.2,,,,,,,ILK_RAT,Rattus norvegicus (Rat),"branching involved in ureteric bud morphogenesis [GO:0001658]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; extracellular fibril organization [GO:0043206]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelin assembly [GO:0032288]; myelination in peripheral nervous system [GO:0022011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of axon extension [GO:0045773]; positive regulation of axonogenesis [GO:0050772]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterooligomerization [GO:0051291]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell growth [GO:0001558]; substrate adhesion-dependent cell spreading [GO:0034446]" comp113127_c0_seq1,535,42.8037,0.28632579,16,37,,2.00E-86,P97386,DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),GO:0005524; GO:0003677; GO:0003910; GO:0006266; GO:0051103; GO:0006310; GO:0006260; GO:0007049; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0043504; GO:0045910; GO:0006289; GO:0005634; GO:0000795; GO:0008270,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation; DNA ligation involved in DNA repair; DNA recombination; DNA replication; cell cycle; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; mitochondrial DNA repair; negative regulation of DNA recombination; nucleotide-excision repair; nucleus; synaptonemal complex; zinc ion binding,PF04679;PF01068;PF04675;PF16759;PF00645;,8.00E-78,CHOYP_BRAFLDRAFT_119901.1.1,,,,,,,DNLI3_MOUSE,Mus musculus (Mouse),"base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of DNA recombination [GO:0045910]; negative regulation of mitochondrial DNA replication [GO:0090298]" comp113137_c1_seq1,607,43.3278,0.3973867,36,16,,3.00E-14,Q9UII4,E3 ISG15--protein ligase HERC5 (EC 6.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5),E3 ISG15--protein ligase HERC5 (EC 6.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5),GO:0042296; GO:0032020; GO:0019221; GO:0005829; GO:0051607; GO:0045087; GO:0032480; GO:0005634; GO:0048471; GO:0042787; GO:0000079; GO:0050688; GO:0004842,ISG15 ligase activity; ISG15-protein conjugation; cytokine-mediated signaling pathway; cytosol; defense response to virus; innate immune response; negative regulation of type I interferon production; nucleus; perinuclear region of cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of defense response to virus; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC5_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; ISG15-protein conjugation [GO:0032020]; negative regulation of type I interferon production [GO:0032480]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of defense response to virus [GO:0050688] comp113157_c1_seq1,250,38,1.35312138,4,15,,,,,,,,,3.00E-15,CHOYP_GSPATT00003195001.1.1,1.00E-11,ruditapes_c15910,,,,,,, comp113158_c0_seq1,371,44.7439,1.14656404,0,7,,3.00E-11,Q8WWN8,"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3)","Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3)",GO:0008060; GO:0005100; GO:0005856; GO:0007010; GO:0005829; GO:0030027; GO:0035021; GO:0035024; GO:0030336; GO:0005547; GO:0043325; GO:0005886; GO:0032312; GO:0008360; GO:0001726; GO:0007264; GO:0016192; GO:0008270,"ARF GTPase activator activity; Rho GTPase activator activity; cytoskeleton; cytoskeleton organization; cytosol; lamellipodium; negative regulation of Rac protein signal transduction; negative regulation of Rho protein signal transduction; negative regulation of cell migration; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; plasma membrane; regulation of ARF GTPase activity; regulation of cell shape; ruffle; small GTPase mediated signal transduction; vesicle-mediated transport; zinc ion binding",PF01412;PF00169;PF00788;PF00620;PF07647;,,,,,,,,,ARAP3_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; negative regulation of cell migration [GO:0030336]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp113158_c0_seq2,675,39.8519,0.80339735,12,48,,5.00E-63,O75689,Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25),Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25),GO:0008060; GO:0007166; GO:0005737; GO:0043533; GO:0005634; GO:0005543; GO:0005886; GO:0032312; GO:0008270,"ARF GTPase activator activity; cell surface receptor signaling pathway; cytoplasm; inositol 1,3,4,5 tetrakisphosphate binding; nucleus; phospholipid binding; plasma membrane; regulation of ARF GTPase activity; zinc ion binding",PF01412;PF00169;,4.00E-13,CHOYP_RLA0.3.7,,,,,,,ADAP1_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; regulation of GTPase activity [GO:0043087] comp113160_c0_seq1,319,49.2163,0.78818509,13,2,,1.00E-21,Q8R4E0,Interferon regulatory factor 2 (IRF-2),Interferon regulatory factor 2 (IRF-2),GO:0005634; GO:0000975; GO:0003700; GO:0006351,"nucleus; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;,,,,,,,,,IRF2_SIGHI,Sigmodon hispidus (Hispid cotton rat),"cell proliferation [GO:0008283]; transcription, DNA-templated [GO:0006351]" comp113180_c0_seq1,230,36.087,0.1365274,6,39,,,,,,,,,5.00E-12,CHOYP_LOC584481.7.10,,,,,,,,, comp113195_c0_seq1,245,40,1.02844523,8,10,,4.00E-08,Q9DBT4,Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.6) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase),Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.6) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase),GO:0000139; GO:0000421; GO:0031410; GO:0016021; GO:0045134,Golgi membrane; autophagic vacuole membrane; cytoplasmic vesicle; integral to membrane; uridine-diphosphatase activity,PF01150;,,,,,,,,,ENTP4_MOUSE,Mus musculus (Mouse),UDP catabolic process [GO:0006256] comp113195_c1_seq1,747,42.9719,1.07446423,15,52,,1.00E-11,O93295,Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase),Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase),GO:0005524; GO:0016787; GO:0016021; GO:0046872; GO:0005886,ATP binding; hydrolase activity; integral to membrane; metal ion binding; plasma membrane,PF01150;,,,,,,,,,ENTP8_CHICK,Gallus gallus (Chicken), comp113195_c2_seq1,301,47.1761,1.03907239,2,37,,2.00E-15,O75354,Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2),Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2),GO:0000139; GO:0009986; GO:0005615; GO:0008894; GO:0016021; GO:0017111; GO:0005886; GO:0051592; GO:0032026; GO:0045134,"Golgi membrane; cell surface; extracellular space; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; integral to membrane; nucleoside-triphosphatase activity; plasma membrane; response to calcium ion; response to magnesium ion; uridine-diphosphatase activity",PF01150;,,,,,,,,,ENTP6_HUMAN,Homo sapiens (Human),response to calcium ion [GO:0051592]; response to magnesium ion [GO:0032026] comp113199_c0_seq1,885,45.3107,0.60336033,5,65,,2.00E-21,Q9NYQ6,Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007417; GO:0048105; GO:0001736; GO:0042249; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity; establishment of planar polarity of embryonic epithelium; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp113204_c0_seq1,590,42.8814,0.87012156,13,66,,2.00E-13,A1L1W9,Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,MOT10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ion transmembrane transport [GO:0034220] comp113217_c0_seq1,647,47.6043,0.32789452,22,13,,9.00E-101,F1NTD6,Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0006307; GO:0008283; GO:0005737; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA dealkylation involved in DNA repair; cell proliferation; cytoplasm; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00270;PF00271;PF02889;,1.00E-101,CHOYP_ASCC3.1.1,,,,,,,ASCC3_CHICK,Gallus gallus (Chicken),"cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp113217_c1_seq1,440,46.3636,0.47657187,23,10,,2.00E-26,P32639,Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246),Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246),GO:0005524; GO:0004004; GO:0046540; GO:0005682; GO:0003676; GO:0005681; GO:0000388,ATP binding; ATP-dependent RNA helicase activity; U4/U6 x U5 tri-snRNP complex; U5 snRNP; nucleic acid binding; spliceosomal complex; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11),PF00270;PF00271;PF02889;,,,,,,,,,BRR2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] comp113227_c0_seq1,452,47.3451,0.95368888,22,18,,1.00E-58,Q60857,Sodium-dependent serotonin transporter (5HT transporter) (5HTT) (Solute carrier family 6 member 4),Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4),GO:0051015; GO:0048854; GO:0071321; GO:0071310; GO:0071300; GO:0007623; GO:0019811; GO:0005829; GO:0012505; GO:0010008; GO:0005887; GO:0045121; GO:0007613; GO:0021941; GO:0045665; GO:0046621; GO:0032227; GO:0043005; GO:0005886; GO:0045787; GO:0010628; GO:0051260; GO:0051259; GO:0042493; GO:0032355; GO:0001666; GO:0007584; GO:0009636; GO:0051610; GO:0005335; GO:0035176; GO:0042713; GO:0021794; GO:0042310,"actin filament binding; brain morphogenesis; cellular response to cGMP; cellular response to organic substance; cellular response to retinoic acid; circadian rhythm; cocaine binding; cytosol; endomembrane system; endosome membrane; integral to plasma membrane; membrane raft; memory; negative regulation of cerebellar granule cell precursor proliferation; negative regulation of neuron differentiation; negative regulation of organ growth; negative regulation of synaptic transmission, dopaminergic; neuron projection; plasma membrane; positive regulation of cell cycle; positive regulation of gene expression; protein homooligomerization; protein oligomerization; response to drug; response to estradiol stimulus; response to hypoxia; response to nutrient; response to toxic substance; serotonin uptake; serotonin:sodium symporter activity; social behavior; sperm ejaculation; thalamus development; vasoconstriction",PF03491;PF00209;,1.00E-41,CHOYP_DERE_GG19936.1.1,,,,,,,SC6A4_MOUSE,Mus musculus (Mouse),"brain morphogenesis [GO:0048854]; cellular response to cGMP [GO:0071321]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; memory [GO:0007613]; monoamine transport [GO:0015844]; negative regulation of cerebellar granule cell precursor proliferation [GO:0021941]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; protein homooligomerization [GO:0051260]; protein oligomerization [GO:0051259]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to toxic substance [GO:0009636]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; social behavior [GO:0035176]; sperm ejaculation [GO:0042713]; thalamus development [GO:0021794]; vasoconstriction [GO:0042310]" comp113227_c1_seq1,346,45.3757,0.53330364,12,0,,5.00E-10,P45320,Uncharacterized sodium-dependent transporter HI_1690,Uncharacterized sodium-dependent transporter HI_1690,GO:0016021; GO:0005328; GO:0005886,integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,,,,,,,,,Y1690_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp113230_c1_seq1,350,34.5714,0.19243578,31,0,,,,,,,,,,,5.00E-12,ruditapes_c21135,,,,,,, comp113233_c0_seq2,435,45.977,0.81750432,5,5,,1.00E-19,P51688,N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),GO:0016250; GO:0005975; GO:0003824; GO:0006027; GO:0043202; GO:0046872; GO:0006029; GO:0044281; GO:0008484,N-sulfoglucosamine sulfohydrolase activity; carbohydrate metabolic process; catalytic activity; glycosaminoglycan catabolic process; lysosomal lumen; metal ion binding; proteoglycan metabolic process; small molecule metabolic process; sulfuric ester hydrolase activity,PF16347;PF00884;,,,,,,,,,SPHM_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] comp113237_c0_seq1,1373,45.0109,0.46157747,58,34,,9.00E-79,Q5ZLG9,WD repeat-containing protein 59,WD repeat-containing protein 59,,,PF00400;,,,,,,,,,WDR59_CHICK,Gallus gallus (Chicken),cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008] comp113237_c1_seq1,284,49.2958,0.42674326,8,7,,5.00E-17,O13686,"Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05","Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05",GO:0000329; GO:0043234; GO:0004842; GO:0008270,fungal-type vacuole membrane; protein complex; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,WDR59_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),positive regulation of TOR signaling [GO:0032008]; protein ubiquitination [GO:0016567] comp113237_c2_seq1,273,49.0842,0.245029,13,4,,2.00E-07,A3LTS5,Protein DSE1 (Daughter-specific expression protein 1),Protein DSE1 (Daughter-specific expression protein 1),GO:0007049; GO:0051301,cell cycle; cell division,PF12894;,5.00E-20,CHOYP_WDR59.4.5,,,,,,,DSE1_PICST,Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis),cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; invasive growth in response to glucose limitation [GO:0001403]; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0010969] comp113242_c0_seq1,627,41.4673,0.33493419,9,44,,2.00E-33,F1M5F3,DNA helicase MCM9 (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9),DNA helicase MCM9 (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9),GO:0005524; GO:0003677; GO:0097362; GO:0000724; GO:0007292; GO:0004386; GO:0005634,ATP binding; DNA binding; MCM8-MCM9 complex; double-strand break repair via homologous recombination; female gamete generation; helicase activity; nucleus,PF00493;,,,,,,,,,MCM9_RAT,Rattus norvegicus (Rat),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; gamete generation [GO:0007276] comp113266_c1_seq2,286,49.6503,0.85672689,0,6,,,,,,,,,2.00E-18,CHOYP_PHUM_PHUM349810.2.2,,,,,,,,, comp113266_c1_seq4,264,46.5909,0.98097653,0,0,,2.00E-22,Q91ZY8,E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),GO:0030054; GO:0005856; GO:0030425; GO:0035544; GO:0045955; GO:0043161; GO:0008021; GO:0016079; GO:0004842; GO:0008270,cell junction; cytoskeleton; dendrite; negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; proteasomal ubiquitin-dependent protein catabolic process; synaptic vesicle; synaptic vesicle exocytosis; ubiquitin-protein ligase activity; zinc ion binding,PF00041;PF00622;PF00643;,2.00E-18,CHOYP_PHUM_PHUM349810.2.2,,,,,,,TRIM9_RAT,Rattus norvegicus (Rat),negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079] comp113272_c0_seq1,300,43.3333,0.57048727,15,0,,4.00E-29,Q17320,Protein white,Protein white,GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0031409; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; pigment binding; transport,PF01061;PF00005;,4.00E-15,CHOYP_WHITE.1.1,,,,,,,WHITE_CERCA,Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata),transport [GO:0006810] comp113274_c0_seq1,802,28.803,0.18061207,80,259,,8.00E-10,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,4.00E-27,CHOYP_NEMVEDRAFT_V1G210604.4.8,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp113323_c1_seq1,336,51.1905,0.46190102,4,0,,,,,,,,,4.00E-15,CHOYP_LOC100929680.1.2,,,,,,,,, comp113349_c0_seq1,511,41.8787,0.36031102,3,28,,3.00E-37,Q7K4B6,Transmembrane and TPR repeat-containing protein CG4050,Transmembrane and TPR repeat-containing protein CG4050,GO:0016021,integral to membrane,PF08409;PF13414;PF13181;,7.00E-21,CHOYP_BRAFLDRAFT_199459.1.1,,,,,,,TMTC3_DROME,Drosophila melanogaster (Fruit fly), comp113354_c0_seq1,2239,37.9187,0.3130801,150,39,,2.00E-100,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,1.00E-26,CHOYP_NEMVEDRAFT_V1G199235.3.15,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp113357_c0_seq1,236,40.678,1.23654394,0,0,,,,,,,,,,,2.00E-14,ruditapes_c24604,,,,,,, comp113363_c0_seq3,558,34.767,0.90074411,6,0,,6.00E-11,Q8IVG5,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_HUMAN,Homo sapiens (Human), comp113367_c0_seq1,336,44.9405,0.6517287,15,12,,5.00E-21,Q2TAA2,Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-),Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-),GO:0016788; GO:0016042,"hydrolase activity, acting on ester bonds; lipid catabolic process",PF13472;,,,,,,,,,IAH1_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042] comp113374_c0_seq1,544,37.1324,0.80780905,18,5,,2.00E-10,O60688,Protein yippee-like 1,Protein yippee-like 1,GO:0051898; GO:0005634; GO:0031641,negative regulation of protein kinase B signaling cascade; nucleus; regulation of myelination,PF03226;,7.00E-15,CHOYP_YPEL1.3.3,,,,,,,YPEL1_HUMAN,Homo sapiens (Human), comp113383_c0_seq2,497,49.6982,0.32715939,6,20,,2.00E-39,Q5FWF4,DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],GO:0005524; GO:0003677; GO:0006281; GO:0036292; GO:0070530; GO:0036310; GO:0004520; GO:0004386; GO:0045910; GO:0043596; GO:0031297; GO:0048478; GO:0009411; GO:0008270,ATP binding; DNA binding; DNA repair; DNA rewinding; K63-linked polyubiquitin binding; annealing helicase activity; endodeoxyribonuclease activity; helicase activity; negative regulation of DNA recombination; nuclear replication fork; replication fork processing; replication fork protection; response to UV; zinc ion binding,PF00271;PF01844;PF00176;PF00641;,4.00E-68,CHOYP_ZRANB3.1.1,,,,,,,ZRAB3_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411] comp113388_c0_seq1,270,49.2593,0.56302711,6,24,,1.00E-06,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,2.00E-12,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp113392_c0_seq1,696,40.8046,0.55441327,28,32,,1.00E-16,Q0EEE2,Patched domain-containing protein 3 (RND-type protein RNDEu-3),Patched domain-containing protein 3 (RND-type protein RNDEu-3),GO:0008158; GO:0016021,hedgehog receptor activity; integral to membrane,PF02460;,1.00E-25,CHOYP_BRAFLDRAFT_74381.1.1,,,,,,,PTHD3_MOUSE,Mus musculus (Mouse), comp113408_c0_seq1,206,57.767,1.35644222,0,12,,8.00E-12,Q9KY04,"Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 2 (GMPMT 2) (EC 2.4.99.16) ((1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase 2)","Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 2 (GMPMT 2) (EC 2.4.99.16) ((1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase 2)",GO:0030979; GO:0043169; GO:0004553; GO:0016758,"alpha-glucan biosynthetic process; cation binding; hydrolase activity, hydrolyzing O-glycosyl compounds; transferase activity, transferring hexosyl groups",PF11896;,,,,,,,,,GLGE2_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),alpha-glucan biosynthetic process [GO:0030979] comp113408_c1_seq1,307,57.9805,1.12778974,0,7,,4.00E-21,B7LRJ2,Putative sialic acid transporter (Sialic acid permease),Putative sialic acid transporter (Sialic acid permease),GO:0015144; GO:0016021; GO:0005886; GO:0015739; GO:0015538,carbohydrate transmembrane transporter activity; integral to membrane; plasma membrane; sialic acid transport; sialic acid:hydrogen symporter activity,PF07690;,,,,,,,,,NANT_ESCF3,Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73),sialic acid transport [GO:0015739] comp113416_c0_seq1,398,41.4573,0.35393482,1,100,,9.00E-06,Q9I8K8,Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5),Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5),GO:0060027; GO:0003007; GO:0016021; GO:0008078; GO:0030336; GO:0005886; GO:0061035; GO:0038036; GO:0003376; GO:0001944,convergent extension involved in gastrulation; heart morphogenesis; integral to membrane; mesodermal cell migration; negative regulation of cell migration; plasma membrane; regulation of cartilage development; sphingosine-1-phosphate receptor activity; sphingosine-1-phosphate signaling pathway; vasculature development,PF00001;,,,,,,,,,S1PR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),anterior lateral line neuromast development [GO:0048901]; anterior lateral line neuromast hair cell development [GO:0035676]; cardioblast migration to the midline involved in heart rudiment formation [GO:0003319]; cell migration involved in gastrulation [GO:0042074]; cell migration involved in heart development [GO:0060973]; cell migration to the midline involved in heart development [GO:0003318]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic viscerocranium morphogenesis [GO:0048703]; endoderm development [GO:0007492]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; heart rudiment formation [GO:0003315]; mesodermal cell migration [GO:0008078]; negative regulation of cell migration [GO:0030336]; otolith development [GO:0048840]; posterior lateral line neuromast hair cell development [GO:0035677]; regulation of cartilage development [GO:0061035]; semicircular canal development [GO:0060872]; sphingosine-1-phosphate signaling pathway [GO:0003376]; vasculature development [GO:0001944] comp113427_c1_seq1,403,45.1613,0.68433573,4,36,,2.00E-21,A4FUD6,Engulfment and cell motility protein 2,Engulfment and cell motility protein 2,GO:0006915; GO:0060326; GO:0005856; GO:0005829; GO:0016020; GO:0006909; GO:0005543,apoptotic process; cell chemotaxis; cytoskeleton; cytosol; membrane; phagocytosis; phospholipid binding,PF11841;PF04727;PF16457;,,,,,,,,,ELMO2_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell chemotaxis [GO:0060326]; cytoskeleton organization [GO:0007010]; phagocytosis [GO:0006909] comp113430_c0_seq1,206,37.8641,0.68228371,19,3,,1.00E-05,Q12955,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0043001; GO:0030315; GO:0007411; GO:0043194; GO:0007409; GO:0016323; GO:0045296; GO:0009986; GO:0043034; GO:0014704; GO:0044325; GO:0016328; GO:0005764; GO:0072660; GO:0071709; GO:0000281; GO:0033268; GO:0033270; GO:0010628; GO:1900827; GO:0045838; GO:2000651; GO:0010765; GO:0045211; GO:0030674; GO:0072661; GO:0019228; GO:0043266; GO:0007165; GO:0030507; GO:0014731; GO:0005200; GO:0050808,"Golgi to plasma membrane protein transport; T-tubule; axon guidance; axon initial segment; axonogenesis; basolateral plasma membrane; cadherin binding; cell surface; costamere; intercalated disc; ion channel binding; lateral plasma membrane; lysosome; maintenance of protein location in plasma membrane; membrane assembly; mitotic cytokinesis; node of Ranvier; paranode region of axon; positive regulation of gene expression; positive regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential; positive regulation of membrane potential; positive regulation of sodium ion transmembrane transporter activity; positive regulation of sodium ion transport; postsynaptic membrane; protein binding, bridging; protein targeting to plasma membrane; regulation of action potential in neuron; regulation of potassium ion transport; signal transduction; spectrin binding; spectrin-associated cytoskeleton; structural constituent of cytoskeleton; synapse organization",PF00023;PF12796;PF13606;PF00531;PF00791;,,,,,,,,,ANK3_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] comp113441_c0_seq1,318,60.3774,1.10764984,1,11,,2.00E-17,P71667,Carboxylesterase NlhH (EC 3.1.1.1),,GO:0004091; GO:0009056; GO:0034338,carboxylesterase activity; catabolic process; short-chain carboxylesterase activity,,,,,,,,,,NLHH_MYCTU,, comp113471_c0_seq1,402,43.7811,0.6265099,10,2,,4.00E-38,Q80TY5,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),GO:0015031,protein transport,PF12624;PF06650;PF16909;,4.00E-35,CHOYP_LOC100371084.1.4,,,,,,,VP13B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp113479_c0_seq7,1271,46.6562,0.39202819,0,0,,,,,,,,,1.00E-22,CHOYP_LOC100367864.2.3,,,,,,,,, comp113488_c0_seq1,454,42.511,0.34695157,30,0,,6.00E-58,Q6AX60,Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),GO:0034464; GO:0060170; GO:0005737; GO:0005815,BBSome; cilium membrane; cytoplasm; microtubule organizing center,PF14728;PF14727;,6.00E-53,CHOYP_PTHB1.1.1,,,,,,,PTHB1_XENLA,Xenopus laevis (African clawed frog), comp113495_c0_seq1,393,37.659,0.7916033,19,19,,2.00E-20,P83088,"Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)","Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)",GO:0032580; GO:0036065; GO:0008417; GO:0016021; GO:0006486,Golgi cisterna membrane; fucosylation; fucosyltransferase activity; integral to membrane; protein glycosylation,PF17039;PF00852;,,,,,,,,,FUCTC_DROME,Drosophila melanogaster (Fruit fly),protein glycosylation [GO:0006486] comp113496_c0_seq1,443,41.0835,0.16534344,20,8,,4.00E-32,Q66J63,Nuclear receptor subfamily 2 group C member 1-B (Developmental orphan receptor 2-B) (DOR2-B) (xDOR2-B) (Orphan nuclear receptor TR2-B) (Testicular receptor 2-B),Nuclear receptor subfamily 2 group C member 1-B (Developmental orphan receptor 2-B) (DOR2-B) (xDOR2-B) (Orphan nuclear receptor TR2-B) (Testicular receptor 2-B),GO:0003677; GO:0030522; GO:0004879; GO:0000122; GO:0005634; GO:0043565; GO:0003707; GO:0008270,DNA binding; intracellular receptor signaling pathway; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,N2C1B_XENLA,Xenopus laevis (African clawed frog),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp113496_c1_seq1,332,46.988,0.33036014,3,0,,3.00E-11,P16376,"Steroid receptor seven-up, isoform A (Nuclear receptor subfamily 2 group F member 3, isoform A)","Steroid receptor seven-up, isoform A (Nuclear receptor subfamily 2 group F member 3, isoform A)",GO:0007462; GO:0007464; GO:0007465; GO:0001078; GO:0007510; GO:0005737; GO:0061331; GO:0007503; GO:0004879; GO:0007270; GO:0005634; GO:0042331; GO:0043565; GO:0003707; GO:0007419; GO:0007601; GO:0008270,R1/R6 cell fate commitment; R3/R4 cell fate commitment; R7 cell fate commitment; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cardioblast cell fate determination; cytoplasm; epithelial cell proliferation involved in Malpighian tubule morphogenesis; fat body development; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; neuron-neuron synaptic transmission; nucleus; phototaxis; sequence-specific DNA binding; steroid hormone receptor activity; ventral cord development; visual perception; zinc ion binding,PF00104;PF00105;,,,,,,,,,7UP2_DROME,Drosophila melanogaster (Fruit fly),"cardioblast cell fate determination [GO:0007510]; central nervous system development [GO:0007417]; compound eye development [GO:0048749]; compound eye photoreceptor fate commitment [GO:0001752]; embryonic development via the syncytial blastoderm [GO:0001700]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; fat body development [GO:0007503]; glial cell development [GO:0021782]; heart development [GO:0007507]; neuroblast development [GO:0014019]; neuron-neuron synaptic transmission [GO:0007270]; photoreceptor cell differentiation [GO:0046530]; phototaxis [GO:0042331]; R1/R6 cell fate commitment [GO:0007462]; R3/R4 cell fate commitment [GO:0007464]; R7 cell fate commitment [GO:0007465]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; visual perception [GO:0007601]" comp113496_c1_seq2,339,47.4926,0.42249513,4,0,,8.00E-42,P55094,Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TR4) (Testicular receptor 4),Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TR4) (Testicular receptor 4),GO:0030154; GO:0005634; GO:0043565; GO:0003700; GO:0007283; GO:0003707; GO:0006351; GO:0008270,"cell differentiation; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; spermatogenesis; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,1.00E-41,CHOYP_LOC100372393.1.1,,,,,,,NR2C2_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp113499_c0_seq1,849,44.7585,0.61739241,46,28,,1.00E-156,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,4.00E-135,CHOYP_BTBD2.1.1,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp113518_c0_seq1,631,45.4834,0.37209396,0,8,,3.00E-44,Q9VLS1,Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,,,,,,,,,KPBB_DROME,Drosophila melanogaster (Fruit fly),glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp113518_c1_seq1,580,43.9655,0.64860029,34,16,,1.00E-62,Q7TSH2,Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,3.00E-64,CHOYP_KPBB.2.2,,,,,,,KPBB_MOUSE,Mus musculus (Mouse),glycogen metabolic process [GO:0005977] comp113530_c0_seq1,332,39.759,0.61171623,0,49,,3.00E-09,Q13332,Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma),Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma),GO:0007155; GO:0021549; GO:0021987; GO:0022038; GO:0030198; GO:0021766; GO:0005887; GO:0021510; GO:0005001,cell adhesion; cerebellum development; cerebral cortex development; corpus callosum development; extracellular matrix organization; hippocampus development; integral to plasma membrane; spinal cord development; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF07679;PF00102;,,,,,,,,,PTPRS_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; spinal cord development [GO:0021510] comp113541_c0_seq1,442,48.19,0.51604207,12,20,,5.00E-43,Q6IDD9,Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog) (dSarm),Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog) (dSarm),GO:0030424; GO:0005737; GO:0045087; GO:0043005; GO:0043025; GO:1901214; GO:0007165,axon; cytoplasm; innate immune response; neuron projection; neuronal cell body; regulation of neuron death; signal transduction,PF07647;PF13676;,5.00E-16,CHOYP_AAEL_AAEL014931.1.1,,,,,,,SARM1_DROME,Drosophila melanogaster (Fruit fly),innate immune response [GO:0045087]; regulation of neuron death [GO:1901214]; response to axon injury [GO:0048678]; signal transduction [GO:0007165] comp113554_c1_seq1,751,39.0146,0.35219246,33,14,,1.00E-21,Q9H8G1,Zinc finger protein 430,Zinc finger protein 430,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN430_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; substantia nigra development [GO:0021762]; transcription, DNA-templated [GO:0006351]" comp113557_c0_seq1,348,59.1954,0.86345751,1,18,,8.00E-16,A0QNG3,Penicillin-binding protein A (PBPA),Penicillin-binding protein A (PBPA),GO:0016021; GO:0008658; GO:0009252; GO:0005886; GO:0008360; GO:0016740,integral to membrane; penicillin binding; peptidoglycan biosynthetic process; plasma membrane; regulation of cell shape; transferase activity,PF00905;,,,,,,,,,PBPA_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp113577_c0_seq1,293,50.1706,0.59889587,7,25,,2.00E-21,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp113584_c0_seq1,651,43.6252,0.96297655,0,6,,2.00E-14,Q9PTA7,Basic phospholipase A2 beta-bungarotoxin A-AL2 chain (Beta-BuTX A-AL2 chain) (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Fragment),Basic phospholipase A2 beta-bungarotoxin A-AL2 chain (Beta-BuTX A-AL2 chain) (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Fragment),GO:0005509; GO:0016042; GO:0072556; GO:0004623; GO:0006644,calcium ion binding; lipid catabolic process; other organism presynaptic membrane; phospholipase A2 activity; phospholipid metabolic process,PF00068;,,,,,,,,,PA2B_BUNMU,Bungarus multicinctus (Many-banded krait),lipid catabolic process [GO:0016042] comp113584_c0_seq2,716,40.0838,0.95270855,8,40,,5.00E-16,Q92086,Acidic phospholipase A2 C (svPLA2) (EC 3.1.1.4) (NAJPLA-2C) (APLA) (Phosphatidylcholine 2-acylhydrolase),Acidic phospholipase A2 C (svPLA2) (EC 3.1.1.4) (NAJPLA-2C) (APLA) (Phosphatidylcholine 2-acylhydrolase),GO:0005509; GO:0005576; GO:0016042; GO:0004623; GO:0006644,calcium ion binding; extracellular region; lipid catabolic process; phospholipase A2 activity; phospholipid metabolic process,PF00068;,,,,,,,,,PA2AC_NAJSP,Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix),lipid catabolic process [GO:0016042] comp113588_c0_seq1,604,37.4172,0.24238848,17,11,,2.00E-18,Q9Y259,Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB),Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB),GO:0005524; GO:0004103; GO:0005829; GO:0004305; GO:0006646,ATP binding; choline kinase activity; cytosol; ethanolamine kinase activity; phosphatidylethanolamine biosynthetic process,,,,,,,,,,CHKB_HUMAN,Homo sapiens (Human),phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646] comp113588_c1_seq1,277,40.7942,0.70919292,3,21,,5.00E-21,P35790,Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82),Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82),GO:0005524; GO:0033265; GO:0004103; GO:0019695; GO:0004104; GO:0005829; GO:0008144; GO:0004305; GO:0006869; GO:0006646; GO:0004871,ATP binding; choline binding; choline kinase activity; choline metabolic process; cholinesterase activity; cytosol; drug binding; ethanolamine kinase activity; lipid transport; phosphatidylethanolamine biosynthetic process; signal transducer activity,,,,,,,,,,CHKA_HUMAN,Homo sapiens (Human),choline metabolic process [GO:0019695]; ethanolamine metabolic process [GO:0006580]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; response to 3-methylcholanthrene [GO:1904681]; response to toxic substance [GO:0009636] comp113598_c0_seq1,522,44.636,0.35904022,0,70,,5.00E-96,Q4KML2,Cryptochrome DASH (Protein CRY-DASH) (zCRY-DASH),Cryptochrome DASH (Protein CRY-DASH) (zCRY-DASH),GO:0003913; GO:0006281; GO:0018298,DNA photolyase activity; DNA repair; protein-chromophore linkage,PF00875;PF03441;,2.00E-73,CHOYP_CRYD.1.1,,,,,,,CRYD_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),photoreactive repair [GO:0000719]; protein-chromophore linkage [GO:0018298] comp113622_c0_seq1,634,42.429,0.49339672,44,33,,8.00E-18,O00716,Transcription factor E2F3 (E2F-3),Transcription factor E2F3 (E2F-3),GO:0001047; GO:0000085; GO:0000278; GO:0005654; GO:0008284; GO:0045893; GO:0003700; GO:0005667; GO:0006367,"core promoter binding; mitotic G2 phase; mitotic cell cycle; nucleoplasm; positive regulation of cell proliferation; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription initiation from RNA polymerase II promoter",PF16421;PF02319;,2.00E-15,CHOYP_E2F3.1.1,,,,,,,E2F3_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp113629_c0_seq1,709,47.8138,0.39966305,6,6,,4.00E-24,Q86VV8,Rotatin,Rotatin,GO:0036064; GO:0005737; GO:0007368,cilium basal body; cytoplasm; determination of left/right symmetry,PF14726;,,,,,,,,,RTTN_HUMAN,Homo sapiens (Human),cilium organization [GO:0044782]; determination of left/right symmetry [GO:0007368] comp113631_c0_seq1,236,44.4915,0.4444941,2,15,,1.00E-20,P38622,Serine/threonine-protein kinase RCK1 (EC 2.7.11.1),Serine/threonine-protein kinase RCK1 (EC 2.7.11.1),GO:0005524; GO:0004674; GO:0040020,ATP binding; protein serine/threonine kinase activity; regulation of meiosis,PF00069;,,,,,,,,,RCK1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein phosphorylation [GO:0006468]; regulation of meiotic nuclear division [GO:0040020] comp113631_c1_seq1,724,36.8785,0.66873821,12,53,,4.00E-73,Q9C098,Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3),Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3),GO:0005524; GO:0005737; GO:0005634; GO:0004674,ATP binding; cytoplasm; nucleus; protein serine/threonine kinase activity,PF00069;,5.00E-101,CHOYP_BRAFLDRAFT_71623.2.2,,,,,,,DCLK3_HUMAN,Homo sapiens (Human), comp113632_c1_seq1,239,46.0251,0.71500755,5,16,,5.00E-13,A6NP11,Zinc finger protein 716,Zinc finger protein 716,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN716_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp11363_c0_seq1,221,42.5339,0.70477633,2,0,,7.00E-09,P40313,Chymotrypsin-like protease CTRL-1 (EC 3.4.21.-),Chymotrypsin-like protease CTRL-1 (EC 3.4.21.-),GO:0007586; GO:0005615; GO:0006508; GO:0004252,digestion; extracellular space; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,CTRL_HUMAN,Homo sapiens (Human),digestion [GO:0007586]; proteolysis [GO:0006508] comp113653_c0_seq1,958,36.8476,0.41327345,50,104,,7.00E-80,Q6YKA8,Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk),Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk),GO:0005070; GO:0005886; GO:0004871,SH3/SH2 adaptor activity; plasma membrane; signal transducer activity,PF00017;PF00018;,3.00E-35,CHOYP_LOC100541322.1.1,,,,,,,DRK_DROSI,Drosophila simulans (Fruit fly), comp113653_c0_seq2,469,36.0341,0.52979307,5,0,,9.00E-12,P53281,LAS seventeen-binding protein 1 (LAS17-binding protein 1),LAS seventeen-binding protein 1 (LAS17-binding protein 1),GO:0030479; GO:0034316; GO:0005634,actin cortical patch; negative regulation of Arp2/3 complex-mediated actin nucleation; nucleus,PF00018;,,,,,,,,,LSB1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316] comp113654_c0_seq1,804,49.5025,1.03737274,36,0,,1.00E-18,Q6P5U7,Leucine-rich repeat and WD repeat-containing protein KIAA1239,NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239),,,PF13271;,2.00E-48,CHOYP_LOC100744637.1.1,,,,,,,K1239_MOUSE,Mus musculus (Mouse), comp113672_c0_seq1,471,44.7983,0.76334576,16,0,,2.00E-18,Q6ZPQ6,"Membrane-associated phosphatidylinositol transfer protein 2 (Drosophila retinal degeneration B homolog 2) (RdgB2) (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)","Membrane-associated phosphatidylinositol transfer protein 2 (Drosophila retinal degeneration B homolog 2) (RdgB2) (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)",GO:0005737; GO:0005856; GO:0012505; GO:0005622; GO:0043231; GO:0016020; GO:0046872; GO:0005543; GO:0006810,cytoplasm; cytoskeleton; endomembrane system; intracellular; intracellular membrane-bounded organelle; membrane; metal ion binding; phospholipid binding; transport,PF02862;PF02121;,1.00E-35,CHOYP_PITM2.2.2,,,,,,,PITM2_MOUSE,Mus musculus (Mouse),transport [GO:0006810] comp113690_c0_seq1,390,47.9487,0.44726901,21,0,,3.00E-14,Q3UVK0,Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina),Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina),GO:0005789; GO:0016021; GO:0046872; GO:0008237; GO:0006508,endoplasmic reticulum membrane; integral to membrane; metal ion binding; metallopeptidase activity; proteolysis,PF04389;,,,,,,,,,ERMP1_MOUSE,Mus musculus (Mouse), comp113691_c1_seq1,789,47.275,0.64038086,38,39,,6.00E-28,Q8BP00,IQ calmodulin-binding motif-containing protein 1,IQ calmodulin-binding motif-containing protein 1,GO:0005516; GO:0005813; GO:0042384; GO:0005737; GO:0048496; GO:0045494; GO:0032391; GO:0001750,calmodulin binding; centrosome; cilium assembly; cytoplasm; maintenance of organ identity; photoreceptor cell maintenance; photoreceptor connecting cilium; photoreceptor outer segment,PF00612;,,,,,,,,,IQCB1_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; maintenance of organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494] comp113737_c0_seq2,889,42.9696,0.30353882,9,31,,7.00E-26,P69310,Ubiquitin,Ubiquitin,GO:0005737; GO:0005634,cytoplasm; nucleus,PF00240;,1.00E-13,CHOYP_LOC101209425.2.2,4.00E-18,ruditapes_lrc16378,,,,,UBIQ_AVESA,Avena sativa (Oat), comp113739_c0_seq1,268,43.2836,0.55975809,5,0,,8.00E-11,Q91V01,Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5),Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5),GO:0047184; GO:0005789; GO:0016021; GO:0008654; GO:0097006,1-acylglycerophosphocholine O-acyltransferase activity; endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process; regulation of plasma lipoprotein particle levels,PF03062;,,,,,,,,,MBOA5_MOUSE,Mus musculus (Mouse),phospholipid biosynthetic process [GO:0008654]; regulation of plasma lipoprotein particle levels [GO:0097006] comp113742_c0_seq1,251,35.8566,0.12500198,1,27,,5.00E-12,Q96RE9,Zinc finger protein 300,Zinc finger protein 300,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN300_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp113747_c0_seq1,378,44.4444,0.5483256,28,18,,5.00E-08,P22981,Ras protein let-60 (Abnormal cell lineage protein 34) (Lethal protein 60),Ras protein let-60 (Abnormal cell lineage protein 34) (Lethal protein 60),GO:0005525; GO:0003924; GO:0017034; GO:0005938; GO:0007173; GO:0007517; GO:0002119; GO:0048477; GO:0005886; GO:0032854; GO:0040026; GO:0042659; GO:0031344; GO:0007264,GTP binding; GTPase activity; Rap guanyl-nucleotide exchange factor activity; cell cortex; epidermal growth factor receptor signaling pathway; muscle organ development; nematode larval development; oogenesis; plasma membrane; positive regulation of Rap GTPase activity; positive regulation of vulval development; regulation of cell fate specification; regulation of cell projection organization; small GTPase mediated signal transduction,PF00071;,,,,,,,,,LET60_CAEEL,Caenorhabditis elegans,associative learning [GO:0008306]; epidermal growth factor receptor signaling pathway [GO:0007173]; muscle organ development [GO:0007517]; nematode larval development [GO:0002119]; oogenesis [GO:0048477]; positive regulation of GTPase activity [GO:0043547]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]; regulation of cell projection organization [GO:0031344]; reproduction [GO:0000003]; short-term memory [GO:0007614]; small GTPase mediated signal transduction [GO:0007264] comp113749_c0_seq1,405,40,0.60577292,0,17,,5.00E-09,Q9EQJ0,Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1),Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1),GO:0072345; GO:0010008; GO:0016021; GO:0005765; GO:0005244,NAADP-sensitive calcium-release channel activity; endosome membrane; integral to membrane; lysosomal membrane; voltage-gated ion channel activity,PF00520;,2.00E-20,CHOYP_LOC567534.1.1,,,,,,,TPC1_MOUSE,Mus musculus (Mouse),membrane depolarization during action potential [GO:0086010]; positive regulation of autophagy [GO:0010508] comp113776_c1_seq2,1326,42.3831,0.63959955,47,28,,7.00E-65,A0JPA0,Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4),Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4),GO:0030554; GO:0016021; GO:0006811; GO:0005886,adenyl nucleotide binding; integral to membrane; ion transport; plasma membrane,PF00571;PF01595;,2.00E-59,CHOYP_LOC100880727.1.1,,,,,,,CNNM4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ion transport [GO:0006811] comp113786_c2_seq1,542,42.8044,0.82080243,6,34,,2.00E-23,Q9QYP0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity,PF00431;PF12947;PF07645;PF00053;PF01437;,6.00E-29,CHOYP_LOC100749345.1.1,,,,,,,MEGF8_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp113814_c1_seq1,1113,42.4978,0.51906852,74,27,,2.00E-70,P04412,Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo),Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo),GO:0005524; GO:0000086; GO:0045466; GO:0007469; GO:0048149; GO:0007298; GO:0007420; GO:0046845; GO:0030031; GO:0016337; GO:0030381; GO:0042676; GO:0001752; GO:0035225; GO:0046843; GO:0007391; GO:0005006; GO:0061331; GO:0035088; GO:0007455; GO:0048139; GO:0007369; GO:0007390; GO:0030718; GO:0008406; GO:0007482; GO:0003015; GO:0008586; GO:0007474; GO:0016021; GO:0007479; GO:0035160; GO:0048140; GO:0008071; GO:0016203; GO:0042694; GO:2000134; GO:0043066; GO:2001234; GO:0046673; GO:0035310; GO:0007477; GO:0001742; GO:0008355; GO:0016318; GO:0007314; GO:0007310; GO:0007422; GO:0005886; GO:0008284; GO:0090303; GO:0007458; GO:0045468; GO:0045610; GO:0007431; GO:0016330; GO:0007367; GO:0035277; GO:0048865; GO:0007421; GO:0035202; GO:0007473,"ATP binding; G2/M transition of mitotic cell cycle; R7 cell differentiation; antennal development; behavioral response to ethanol; border follicle cell migration; brain development; branched duct epithelial cell fate determination, open tracheal system; cell projection assembly; cell-cell adhesion; chorion-containing eggshell pattern formation; compound eye cone cell fate commitment; compound eye photoreceptor fate commitment; determination of genital disc primordium; dorsal appendage formation; dorsal closure; epidermal growth factor-activated receptor activity; epithelial cell proliferation involved in Malpighian tubule morphogenesis; establishment or maintenance of apical/basal cell polarity; eye-antennal disc morphogenesis; female germ-line cyst encapsulation; gastrulation; germ-band shortening; germ-line stem cell maintenance; gonad development; haltere development; heart process; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; leg disc proximal/distal pattern formation; maintenance of epithelial integrity, open tracheal system; male germ-line cyst encapsulation; maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded; muscle attachment; muscle cell fate specification; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of apoptotic process; negative regulation of apoptotic signaling pathway; negative regulation of compound eye retinal cell programmed cell death; notum cell fate specification; notum development; oenocyte differentiation; olfactory learning; ommatidial rotation; oocyte anterior/posterior axis specification; oocyte dorsal/ventral axis specification; peripheral nervous system development; plasma membrane; positive regulation of cell proliferation; positive regulation of wound healing; progression of morphogenetic furrow involved in compound eye morphogenesis; regulation of R8 cell spacing in compound eye; regulation of hemocyte differentiation; salivary gland development; second mitotic wave involved in compound eye morphogenesis; segment polarity determination; spiracle morphogenesis, open tracheal system; stem cell fate commitment; stomatogastric nervous system development; tracheal pit formation in open tracheal system; wing disc proximal/distal pattern formation",PF00757;PF14843;PF07714;PF01030;,,,,,,,,,EGFR_DROME,Drosophila melanogaster (Fruit fly),"antennal development [GO:0007469]; anterior/posterior pattern specification [GO:0009952]; behavioral response to ethanol [GO:0048149]; blastoderm segmentation [GO:0007350]; border follicle cell migration [GO:0007298]; brain development [GO:0007420]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; cell projection assembly [GO:0030031]; chorion-containing eggshell pattern formation [GO:0030381]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; compound eye photoreceptor fate commitment [GO:0001752]; determination of adult lifespan [GO:0008340]; determination of genital disc primordium [GO:0035225]; digestive tract morphogenesis [GO:0048546]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic axis specification [GO:0000578]; embryonic pattern specification [GO:0009880]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; eye-antennal disc morphogenesis [GO:0007455]; eye development [GO:0001654]; female germ-line cyst encapsulation [GO:0048139]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; germ-band shortening [GO:0007390]; germ-line stem cell population maintenance [GO:0030718]; gonad development [GO:0008406]; gurken signaling pathway [GO:0008314]; haltere development [GO:0007482]; heart process [GO:0003015]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc development [GO:0007444]; imaginal disc pattern formation [GO:0007447]; leg disc proximal/distal pattern formation [GO:0007479]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; male germ-line cyst encapsulation [GO:0048140]; Malpighian tubule morphogenesis [GO:0007443]; maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded [GO:0008071]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of follicular epithelium [GO:0016333]; muscle attachment [GO:0016203]; muscle cell fate specification [GO:0042694]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neurogenesis [GO:0022008]; notum cell fate specification [GO:0035310]; notum development [GO:0007477]; oenocyte differentiation [GO:0001742]; olfactory learning [GO:0008355]; ommatidial rotation [GO:0016318]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte axis specification [GO:0007309]; oocyte dorsal/ventral axis specification [GO:0007310]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of wound healing [GO:0090303]; progression of morphogenetic furrow involved in compound eye morphogenesis [GO:0007458]; protein phosphorylation [GO:0006468]; R7 cell differentiation [GO:0045466]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte differentiation [GO:0045610]; regulation of mitotic cell cycle [GO:0007346]; regulation of R8 cell spacing in compound eye [GO:0045468]; salivary gland development [GO:0007431]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; segment polarity determination [GO:0007367]; single organismal cell-cell adhesion [GO:0016337]; spiracle morphogenesis, open tracheal system [GO:0035277]; stem cell fate commitment [GO:0048865]; stomatogastric nervous system development [GO:0007421]; tracheal pit formation in open tracheal system [GO:0035202]; wing and notum subfield formation [GO:0035309]; wing disc morphogenesis [GO:0007472]; wing disc proximal/distal pattern formation [GO:0007473]" comp113815_c0_seq1,856,42.1729,0.34483766,19,42,,8.00E-127,Q6GM29,Phosphatidylinositide phosphatase SAC1 (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein),Phosphatidylinositide phosphatase SAC1 (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein),GO:0005789; GO:0016021; GO:0016791,endoplasmic reticulum membrane; integral to membrane; phosphatase activity,PF02383;,5.00E-83,CHOYP_SAC1.1.1,,,,,,,SAC1_XENLA,Xenopus laevis (African clawed frog),phosphatidylinositol dephosphorylation [GO:0046856] comp113835_c0_seq1,332,33.1325,0.221338,25,0,,6.00E-06,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp113864_c1_seq1,427,46.8384,0.43149748,10,6,,1.00E-11,Q8K4G1,Latent-transforming growth factor beta-binding protein 4 (LTBP-4),Latent-transforming growth factor beta-binding protein 4 (LTBP-4),GO:0005509; GO:0005615; GO:0046879; GO:0005578; GO:0030162; GO:0007179,calcium ion binding; extracellular space; hormone secretion; proteinaceous extracellular matrix; regulation of proteolysis; transforming growth factor beta receptor signaling pathway,PF07645;PF00683;,,,,,,,,,LTBP4_MOUSE,Mus musculus (Mouse),hormone secretion [GO:0046879]; regulation of proteolysis [GO:0030162]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp113868_c0_seq1,552,42.5725,0.49032228,12,34,,1.00E-68,P70699,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),GO:0004558; GO:0030246; GO:0060048; GO:0002086; GO:0005980; GO:0003007; GO:0007626; GO:0005765; GO:0005764; GO:0007040; GO:0032450; GO:0046716; GO:0050885; GO:0050884; GO:0002026; GO:0009888; GO:0043587; GO:0043181; GO:0055010,alpha-glucosidase activity; carbohydrate binding; cardiac muscle contraction; diaphragm contraction; glycogen catabolic process; heart morphogenesis; locomotory behavior; lysosomal membrane; lysosome; lysosome organization; maltose alpha-glucosidase activity; muscle cell cellular homeostasis; neuromuscular process controlling balance; neuromuscular process controlling posture; regulation of the force of heart contraction; tissue development; tongue morphogenesis; vacuolar sequestering; ventricular cardiac muscle tissue morphogenesis,PF13802;PF01055;PF16863;PF00088;,1.00E-25,CHOYP_LOC100553663.1.1,,,,,,,LYAG_MOUSE,Mus musculus (Mouse),cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; striated muscle contraction [GO:0006941]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] comp113871_c0_seq4,572,41.958,0.9604052,0,0,,,,,,,,,,,7.00E-13,ruditapes_c11147,,,,,,, comp113871_c1_seq1,402,48.2587,0.820867,17,0,,4.00E-10,Q12603,"Beta-1,4-xylanase (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase) (Endo-1,4-beta-xylanase)","Beta-1,4-xylanase (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase) (Endo-1,4-beta-xylanase)",GO:0031176; GO:0005576; GO:0045493,"endo-1,4-beta-xylanase activity; extracellular region; xylan catabolic process",PF00331;,,,,,,,,,XYNA_DICTH,Dictyoglomus thermophilum,xylan catabolic process [GO:0045493] comp113875_c0_seq1,592,39.0203,0.41584971,19,32,,9.00E-68,P62071,Ras-related protein R-Ras2,Ras-related protein R-Ras2,GO:0005525; GO:0003924; GO:0007265; GO:0005622; GO:0005886; GO:0030335,GTP binding; GTPase activity; Ras protein signal transduction; intracellular; plasma membrane; positive regulation of cell migration,PF00071;,1.00E-43,CHOYP_BRAFLDRAFT_199337.1.1,,,,,,,RRAS2_MOUSE,Mus musculus (Mouse),cellular process [GO:0009987]; osteoblast differentiation [GO:0001649]; positive regulation of cell migration [GO:0030335]; Ras protein signal transduction [GO:0007265]; regulation of neuron death [GO:1901214] comp113877_c2_seq1,228,42.1053,0.6435721,2,10,,2.00E-09,Q94IG7,"Protoporphyrinogen oxidase, chloroplastic/mitochondrial (Protox II) (EC 1.3.3.4) (SO-POX2)","Protoporphyrinogen oxidase, chloroplastic/mitochondrial (Protox II) (EC 1.3.3.4) (SO-POX2)",GO:0015995; GO:0009706; GO:0006783; GO:0005743; GO:0004729; GO:0006782,chlorophyll biosynthetic process; chloroplast inner membrane; heme biosynthetic process; mitochondrial inner membrane; oxygen-dependent protoporphyrinogen oxidase activity; protoporphyrinogen IX biosynthetic process,PF01593;,,,,,,,,,PPOCM_SPIOL,Spinacia oleracea (Spinach),chlorophyll biosynthetic process [GO:0015995]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] comp113877_c3_seq1,402,42.5373,0.62701944,2,47,,6.00E-26,P50336,Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4),Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4),GO:0050660; GO:0006783; GO:0031305; GO:0031304; GO:0005758; GO:0004729; GO:0006782; GO:0042493; GO:0044281,flavin adenine dinucleotide binding; heme biosynthetic process; integral to mitochondrial inner membrane; intrinsic to mitochondrial inner membrane; mitochondrial intermembrane space; oxygen-dependent protoporphyrinogen oxidase activity; protoporphyrinogen IX biosynthetic process; response to drug; small molecule metabolic process,PF01593;,,,,,,,,,PPOX_HUMAN,Homo sapiens (Human),heme biosynthetic process [GO:0006783]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to drug [GO:0042493] comp113877_c4_seq1,311,42.1222,0.51052421,9,20,,4.00E-12,P51175,Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4),Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4),GO:0006783; GO:0031304; GO:0004729; GO:0006782,heme biosynthetic process; intrinsic to mitochondrial inner membrane; oxygen-dependent protoporphyrinogen oxidase activity; protoporphyrinogen IX biosynthetic process,PF01593;,,,,,,,,,PPOX_MOUSE,Mus musculus (Mouse),heme biosynthetic process [GO:0006783]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to drug [GO:0042493] comp113893_c0_seq1,314,40.7643,0.69828294,0,34,,6.00E-08,P0CJ62,RBPJ-interacting and tubulin-associated protein,RBPJ-interacting and tubulin-associated protein 1 (RBPJ-interacting and tubulin-associated protein),GO:0007219; GO:0005737; GO:0045746; GO:0000122; GO:0022008; GO:0051168; GO:0005634; GO:0015631,Notch signaling pathway; cytoplasm; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neurogenesis; nuclear export; nucleus; tubulin binding,PF17066;,,,,,,,,,RITA_XENLA,Xenopus laevis (African clawed frog),negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; nuclear export [GO:0051168] comp113897_c1_seq1,429,34.2657,0.40983829,12,21,,2.00E-06,Q5RB35,Muskelin,Muskelin,GO:0005737,cytoplasm,PF01344;PF06588;,,,,,,,,,MKLN1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360] comp113903_c0_seq1,944,43.9619,0.57065281,32,10,,2.00E-71,Q5XIX3,Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (SNM1-like protein),Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (SNM1-like protein),GO:0008409; GO:0030183; GO:0006310; GO:0006302; GO:0090305; GO:0005634; GO:0010212; GO:0000014; GO:0000723,5'-3' exonuclease activity; B cell differentiation; DNA recombination; double-strand break repair; nucleic acid phosphodiester bond hydrolysis; nucleus; response to ionizing radiation; single-stranded DNA endodeoxyribonuclease activity; telomere maintenance,PF07522;,,,,,,,,,DCR1C_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; response to ionizing radiation [GO:0010212]; V(D)J recombination [GO:0033151] comp113914_c0_seq1,564,40.6028,0.47888885,29,0,,2.00E-46,Q9D2I5,LisH domain-containing protein ARMC9,LisH domain-containing protein ARMC9,,,,3.00E-38,CHOYP_ARMC9.1.1,,,,,,,ARMC9_MOUSE,Mus musculus (Mouse), comp113927_c0_seq1,932,38.9485,0.85591194,31,181,,8.00E-25,Q9VUY0,MOXD1 homolog 1 (EC 1.14.17.-),MOXD1 homolog 1 (EC 1.14.17.-),GO:0006584; GO:0005507; GO:0004500; GO:0005576,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; extracellular region,PF03712;PF01082;PF03351;,,,,,,,,,MOX11_DROME,Drosophila melanogaster (Fruit fly), comp113927_c1_seq1,460,44.5652,0.70288116,6,45,,3.00E-34,Q5TZ24,DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-),DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp113931_c0_seq4,2182,44.3171,0.4814984,0,0,,2.00E-75,Q9NGQ2,Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),GO:0005524; GO:0030659; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005543; GO:0006810,ATP binding; cytoplasmic vesicle membrane; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; phospholipid binding; transport,PF00225;PF16183;PF00169;,7.00E-111,CHOYP_LOC100366906.1.1,,,,,,,KIF1_DICDI,Dictyostelium discoideum (Slime mold),plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496] comp113931_c0_seq5,2209,44.5903,0.48910966,0,0,,3.00E-123,F8WLE0,Kinesin-like protein KLP6 (Kinesin-like protein 6),Kinesin-like protein KIF28P (Kinesin-like protein 6),GO:0005524; GO:0005871; GO:0003777; GO:0031966; GO:0007005; GO:0072384,ATP binding; kinesin complex; microtubule motor activity; mitochondrial membrane; mitochondrion organization; organelle transport along microtubule,PF00498;PF12423;PF00225;,7.00E-111,CHOYP_LOC100366906.1.1,,,,,,,KLP6_RAT,Rattus norvegicus (Rat),mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] comp113931_c1_seq1,359,45.6825,0.59326303,6,0,,4.00E-29,Q9NGQ2,Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),GO:0005524; GO:0030659; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005543; GO:0006810,ATP binding; cytoplasmic vesicle membrane; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; phospholipid binding; transport,PF00225;PF16183;PF00169;,,,,,,,,,KIF1_DICDI,Dictyostelium discoideum (Slime mold),plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496] comp113935_c1_seq1,261,46.7433,0.21405543,1,31,,2.00E-10,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp113938_c0_seq2,396,49.4949,0.29946312,21,19,,6.00E-23,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,,,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp11393_c0_seq1,366,43.7158,0.59733519,8,0,,8.00E-11,Q5RFQ6,Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2),Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2),GO:0005604; GO:0003682; GO:0005694; GO:0030199; GO:0005507; GO:0043542; GO:0001935; GO:0001837; GO:0005615; GO:0016570; GO:0016020; GO:0035064; GO:0045892; GO:0005634; GO:0070492; GO:0032332; GO:0018277; GO:0004720; GO:0046688; GO:0001666; GO:0005044; GO:0002040; GO:0003714; GO:0006351,"basement membrane; chromatin binding; chromosome; collagen fibril organization; copper ion binding; endothelial cell migration; endothelial cell proliferation; epithelial to mesenchymal transition; extracellular space; histone modification; membrane; methylated histone residue binding; negative regulation of transcription, DNA-dependent; nucleus; oligosaccharide binding; positive regulation of chondrocyte differentiation; protein deamination; protein-lysine 6-oxidase activity; response to copper ion; response to hypoxia; scavenger receptor activity; sprouting angiogenesis; transcription corepressor activity; transcription, DNA-dependent",PF01186;PF00530;,,,,,,,,,LOXL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cellular protein modification process [GO:0006464]; collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; histone modification [GO:0016570]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidation-reduction process [GO:0055114]; positive regulation of chondrocyte differentiation [GO:0032332]; protein deamination [GO:0018277]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp113940_c0_seq1,207,39.1304,0.63416114,3,5,,2.00E-13,Q04666,Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy-like protein) (RHL),Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy-like protein) (RHL),GO:0071820; GO:0001078; GO:0007262; GO:0021861; GO:2000978; GO:0060253; GO:0048715; GO:2000974; GO:0097150; GO:0005654; GO:0043388; GO:0048711; GO:0042517; GO:0006461; GO:0042803; GO:0043565,N-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; STAT protein import into nucleus; forebrain radial glial cell differentiation; negative regulation of forebrain neuron differentiation; negative regulation of glial cell proliferation; negative regulation of oligodendrocyte differentiation; negative regulation of pro-B cell differentiation; neuronal stem cell maintenance; nucleoplasm; positive regulation of DNA binding; positive regulation of astrocyte differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein; protein complex assembly; protein homodimerization activity; sequence-specific DNA binding,PF07527;PF00010;,,,,,,,,,HES1_RAT,Rattus norvegicus (Rat),"cellular response to fatty acid [GO:0071398]; cellular response to interleukin-1 [GO:0071347]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; forebrain radial glial cell differentiation [GO:0021861]; hair cell differentiation [GO:0035315]; negative regulation of calcium ion import [GO:0090281]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; neuron differentiation [GO:0030182]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; protein complex assembly [GO:0006461]; regulation of protein heterodimerization activity [GO:0043497]; response to alkaloid [GO:0043279]; response to organic cyclic compound [GO:0014070]; response to thyroid hormone [GO:0097066]; STAT protein import into nucleus [GO:0007262]; transcription, DNA-templated [GO:0006351]" comp113954_c1_seq1,367,42.2343,0.44034515,12,18,,4.00E-19,Q9R1W3,E3 ubiquitin-protein ligase RNF103 (EC 6.3.2.-) (KF-1) (mKF-1) (RING finger protein 103) (Zinc finger protein 103) (Zfp-103),E3 ubiquitin-protein ligase RNF103 (EC 6.3.2.-) (KF-1) (mKF-1) (RING finger protein 103) (Zinc finger protein 103) (Zfp-103),GO:0030433; GO:0005783; GO:0005789; GO:0016021; GO:0004842; GO:0008270,ER-associated protein catabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,RN103_MOUSE,Mus musculus (Mouse),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567] comp113955_c0_seq1,1142,44.2207,0.42378406,47,63,,4.00E-14,Q3LAC4,"Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2)","Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2)",GO:0007186; GO:0030675; GO:0030676; GO:0035556; GO:0005543,G-protein coupled receptor signaling pathway; Rac GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; intracellular signal transduction; phospholipid binding,PF00610;PF00169;PF00621;,4.00E-130,CHOYP_SOS1.1.1,,,,,,,PREX2_MOUSE,Mus musculus (Mouse),adult locomotory behavior [GO:0008344]; dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphatidylinositol 3-kinase signaling [GO:0014065]; regulation of Rho protein signal transduction [GO:0035023] comp113955_c1_seq1,1220,41.3115,0.59845411,9,29,,3.00E-167,Q62245,Son of sevenless homolog 1 (SOS-1) (mSOS-1),Son of sevenless homolog 1 (SOS-1) (mSOS-1),GO:0003677; GO:0005088; GO:0005089; GO:0005829; GO:0005543; GO:0035023; GO:0007264,DNA binding; Ras guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; cytosol; phospholipid binding; regulation of Rho protein signal transduction; small GTPase mediated signal transduction,PF00125;PF00169;PF00617;PF00618;PF00621;,4.00E-136,CHOYP_SOS1.1.1,,,,,,,SOS1_MOUSE,Mus musculus (Mouse),B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; heart trabecula morphogenesis [GO:0061384]; lymphocyte homeostasis [GO:0002260]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264]; vitellogenesis [GO:0007296] comp113955_c1_seq2,650,50.3077,0.53670824,22,55,,,,,,,,,,,7.00E-33,ruditapes_c24046,,,,,,, comp113955_c1_seq3,1008,40.4762,0.60731973,3,0,,6.00E-134,Q62245,Son of sevenless homolog 1 (SOS-1) (mSOS-1),Son of sevenless homolog 1 (SOS-1) (mSOS-1),GO:0003677; GO:0005088; GO:0005089; GO:0005829; GO:0005543; GO:0035023; GO:0007264,DNA binding; Ras guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; cytosol; phospholipid binding; regulation of Rho protein signal transduction; small GTPase mediated signal transduction,PF00125;PF00169;PF00617;PF00618;PF00621;,,,,,,,,,SOS1_MOUSE,Mus musculus (Mouse),B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; heart trabecula morphogenesis [GO:0061384]; lymphocyte homeostasis [GO:0002260]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264]; vitellogenesis [GO:0007296] comp113957_c0_seq1,607,32.1252,0.64000174,1,102,,8.00E-06,Q18007,Probable muscarinic acetylcholine receptor gar-1 (G-protein-linked acetylcholine receptor 1),Probable muscarinic acetylcholine receptor gar-1 (G-protein-linked acetylcholine receptor 1),GO:0016907; GO:0005887; GO:0045211; GO:0007271,"G-protein coupled acetylcholine receptor activity; integral to plasma membrane; postsynaptic membrane; synaptic transmission, cholinergic",PF00001;,,,7.00E-39,ruditapes_c13658,,,,,ACM1_CAEEL,Caenorhabditis elegans,"synaptic transmission, cholinergic [GO:0007271]" comp113970_c0_seq1,321,44.5483,0.37808586,21,12,,1.00E-42,Q0IJ05,Oxysterol-binding protein-related protein 9,Oxysterol-binding protein-related protein 9,GO:0006869; GO:0005543,lipid transport; phospholipid binding,PF01237;PF00169;,,,,,,,,,OSBL9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),lipid transport [GO:0006869] comp113970_c2_seq1,678,42.7729,0.45524739,33,26,,3.00E-28,Q8CI95,Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),GO:0005794; GO:0031902; GO:0006869; GO:0005543,Golgi apparatus; late endosome membrane; lipid transport; phospholipid binding,PF01237;PF00169;,6.00E-55,CHOYP_OSBL9.1.2,,,,,,,OSB11_MOUSE,Mus musculus (Mouse),fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890] comp113971_c0_seq2,334,48.2036,0.52148662,11,3,,,,,,,,,9.00E-24,CHOYP_LOC100377058.1.1,,,,,,,,, comp113971_c1_seq1,897,46.1538,0.63160935,38,29,,4.00E-25,Q6ZRR9,Doublecortin domain-containing protein 5,Doublecortin domain-containing protein 5,GO:0035556,intracellular signal transduction,,,,,,,,,,DCDC5_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp113984_c0_seq1,747,65.7296,1.11801443,0,60,,5.00E-76,Q03961,Polysialic acid transport protein KpsD,Polysialic acid transport protein KpsD,GO:0016020; GO:0042597; GO:0015159,membrane; periplasmic space; polysaccharide transmembrane transporter activity,PF02563;PF10531;,,,,,,,,,KPSD1_ECOLX,Escherichia coli, comp113995_c0_seq1,412,43.6893,0.86947881,8,29,,2.00E-37,Q3USW5,FAD-dependent oxidoreductase domain-containing protein 2,FAD-dependent oxidoreductase domain-containing protein 2,GO:0030433; GO:0005788; GO:0050660; GO:0016491,ER-associated protein catabolic process; endoplasmic reticulum lumen; flavin adenine dinucleotide binding; oxidoreductase activity,,,,,,,,,,FXRD2_MOUSE,Mus musculus (Mouse),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114] comp114001_c0_seq1,782,46.1637,0.48261913,0,0,,,,,,,,,9.00E-54,CHOYP_LOC584931.1.1,,,,,,,,, comp114001_c0_seq2,942,43.7367,0.51503193,0,0,,2.00E-51,Q0IHF9,Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (Transmembrane protein 66),Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (Transmembrane protein 66),GO:0030176; GO:2001256; GO:0015279,integral to endoplasmic reticulum membrane; regulation of store-operated calcium entry; store-operated calcium channel activity,PF06682;,1.00E-53,CHOYP_LOC584931.1.1,,,,,,,SARAF_XENLA,Xenopus laevis (African clawed frog),calcium ion transport [GO:0006816]; regulation of store-operated calcium entry [GO:2001256] comp114016_c1_seq1,249,44.1767,0.50404039,2,0,,1.00E-10,P54697,Myosin-J heavy chain (Myosin-5b),Myosin-J heavy chain (Myosin-5b),GO:0043531; GO:0005524; GO:0051015; GO:0030898; GO:0033275; GO:0042641; GO:0000331; GO:0000146; GO:0016459,ADP binding; ATP binding; actin filament binding; actin-dependent ATPase activity; actin-myosin filament sliding; actomyosin; contractile vacuole; microfilament motor activity; myosin complex,PF01843;PF00612;PF00063;PF02736;,,,,,,,,,MYOJ_DICDI,Dictyostelium discoideum (Slime mold),actin-myosin filament sliding [GO:0033275] comp114021_c1_seq1,345,50.7246,0.36183311,4,34,,6.00E-16,Q5JWR5,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,4.00E-41,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp114034_c1_seq1,242,43.3884,1.14707841,0,23,,4.00E-10,P57748,Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin),Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin),GO:0097186; GO:0005509; GO:0022617; GO:0004222; GO:0030163; GO:0005578; GO:0006508; GO:0008270,amelogenesis; calcium ion binding; extracellular matrix disassembly; metalloendopeptidase activity; protein catabolic process; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF00045;PF00413;PF01471;,,,,,,,,,MMP20_MOUSE,Mus musculus (Mouse),amelogenesis [GO:0097186]; extracellular matrix disassembly [GO:0022617]; protein catabolic process [GO:0030163] comp114039_c0_seq1,229,40.1747,0.10916202,5,17,,,,,,,,,4.00E-20,CHOYP_INPP5B.1.1,,,,,,,,, comp114039_c1_seq2,843,40.9253,0.26144458,8,0,,1.00E-88,Q01968,Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein),Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein),GO:0005795; GO:0005798; GO:0030675; GO:0042384; GO:0030136; GO:0005905; GO:0005829; GO:0005769; GO:0031901; GO:0001701; GO:0043647; GO:0052745; GO:0005634; GO:0030670; GO:0006661; GO:0046856; GO:0004439; GO:0001750; GO:0005886; GO:0032314; GO:0007264; GO:0005802,"Golgi stack; Golgi-associated vesicle; Rac GTPase activator activity; cilium assembly; clathrin-coated vesicle; coated pit; cytosol; early endosome; early endosome membrane; in utero embryonic development; inositol phosphate metabolic process; inositol phosphate phosphatase activity; nucleus; phagocytic vesicle membrane; phosphatidylinositol biosynthetic process; phosphatidylinositol dephosphorylation; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; photoreceptor outer segment; plasma membrane; regulation of Rac GTPase activity; small GTPase mediated signal transduction; trans-Golgi network",PF03372;PF16726;PF00620;,9.00E-29,CHOYP_INPP5B.1.1,,,,,,,OCRL_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp114042_c0_seq1,430,40.6977,0.45368666,10,5,,4.00E-40,Q9HC77,Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1),Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1),GO:0000086; GO:0051301; GO:0005814; GO:0007099; GO:0005829; GO:0008275; GO:0005874; GO:0007020; GO:0046785; GO:0046599; GO:0015631,G2/M transition of mitotic cell cycle; cell division; centriole; centriole replication; cytosol; gamma-tubulin small complex; microtubule; microtubule nucleation; microtubule polymerization; regulation of centriole replication; tubulin binding,PF07202;,2.00E-51,CHOYP_CENPJ.1.1,,,,,,,CENPJ_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; regulation of centriole replication [GO:0046599]" comp114044_c0_seq1,683,42.4597,0.62673745,27,31,,1.00E-09,P28028,Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf),Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf),GO:0005524; GO:0043367; GO:0005509; GO:0044297; GO:0071277; GO:0035556; GO:0060291; GO:0005739; GO:0002318; GO:2000352; GO:0010764; GO:0043524; GO:2000301; GO:0043005; GO:0005634; GO:0005886; GO:0043368; GO:0070374; GO:0010628; GO:0033138; GO:0051496; GO:1900026; GO:0004672; GO:0004674; GO:0005057; GO:0042127; GO:0070849; GO:0035019; GO:0008542,"ATP binding; CD4-positive, alpha-beta T cell differentiation; calcium ion binding; cell body; cellular response to calcium ion; intracellular signal transduction; long-term synaptic potentiation; mitochondrion; myeloid progenitor cell differentiation; negative regulation of endothelial cell apoptotic process; negative regulation of fibroblast migration; negative regulation of neuron apoptotic process; negative regulation of synaptic vesicle exocytosis; neuron projection; nucleus; plasma membrane; positive T cell selection; positive regulation of ERK1 and ERK2 cascade; positive regulation of gene expression; positive regulation of peptidyl-serine phosphorylation; positive regulation of stress fiber assembly; positive regulation of substrate adhesion-dependent cell spreading; protein kinase activity; protein serine/threonine kinase activity; receptor signaling protein activity; regulation of cell proliferation; response to epidermal growth factor stimulus; somatic stem cell maintenance; visual learning",PF00130;PF07714;PF02196;,,,,,,,,,BRAF_MOUSE,Mus musculus (Mouse),"alpha-beta T cell differentiation [GO:0046632]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; establishment of protein localization to membrane [GO:0090150]; face development [GO:0060324]; glucose transport [GO:0015758]; head morphogenesis [GO:0060323]; long-term synaptic potentiation [GO:0060291]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of axonogenesis [GO:0050772]; positive regulation of axon regeneration [GO:0048680]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive T cell selection [GO:0043368]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; regulation of cell proliferation [GO:0042127]; response to cAMP [GO:0051591]; response to peptide hormone [GO:0043434]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; visual learning [GO:0008542]" comp114047_c1_seq1,498,44.7791,0.64221623,28,0,,2.00E-38,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,8.00E-33,CHOYP_LOC592001.1.1,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp114050_c0_seq1,524,43.3206,0.46497754,14,36,,4.00E-45,Q503I8,Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase),Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase),GO:0005737; GO:0006516; GO:0046872; GO:0000224,cytoplasm; glycoprotein catabolic process; metal ion binding; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity,PF04721;PF09409;PF01841;,,,,,,,,,NGLY1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glycoprotein catabolic process [GO:0006516] comp114058_c0_seq1,951,44.9001,0.63183115,33,26,,2.00E-84,Q8N5D0,WD and tetratricopeptide repeats protein 1,WD and tetratricopeptide repeats protein 1,GO:0055082; GO:0032869; GO:0005829; GO:0004857; GO:0006006; GO:0001701; GO:0043231; GO:0035264; GO:0045717; GO:0000122; GO:0005634; GO:0008361,cellular chemical homeostasis; cellular response to insulin stimulus; cytosol; enzyme inhibitor activity; glucose metabolic process; in utero embryonic development; intracellular membrane-bounded organelle; multicellular organism growth; negative regulation of fatty acid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of cell size,PF00400;,,,,,,,,,WDTC1_HUMAN,Homo sapiens (Human),cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361] comp114076_c0_seq1,643,43.0793,0.74678654,37,53,,3.00E-68,Q6ZV73,"FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)","FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)",GO:0005794; GO:0005089; GO:0030036; GO:0005856; GO:0046847; GO:0005085; GO:0030027; GO:0046872; GO:0005543; GO:0043088; GO:0008360; GO:0001726; GO:0031267,Golgi apparatus; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cytoskeleton; filopodium assembly; guanyl-nucleotide exchange factor activity; lamellipodium; metal ion binding; phospholipid binding; regulation of Cdc42 GTPase activity; regulation of cell shape; ruffle; small GTPase binding,PF01363;PF00169;PF00621;,1.00E-26,CHOYP_FGD6.1.1,,,,,,,FGD6_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023] comp114080_c0_seq1,259,54.4402,0.47083197,4,3,,2.00E-41,Q8TAM2,Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein),Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein),GO:0034464; GO:0007411; GO:0060219; GO:0005813; GO:0005929; GO:0042384; GO:0060170; GO:0005737; GO:0048560; GO:0045444; GO:0005932; GO:0035264; GO:0021772; GO:0032391; GO:0032880; GO:0061326; GO:0007608; GO:0050893,BBSome; axon guidance; camera-type eye photoreceptor cell differentiation; centrosome; cilium; cilium assembly; cilium membrane; cytoplasm; establishment of anatomical structure orientation; fat cell differentiation; microtubule basal body; multicellular organism growth; olfactory bulb development; photoreceptor connecting cilium; regulation of protein localization; renal tubule development; sensory perception of smell; sensory processing,PF13176;,,,,,,,,,TTC8_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; establishment of anatomical structure orientation [GO:0048560]; protein transport [GO:0015031]; sensory processing [GO:0050893] comp114080_c1_seq1,337,44.5104,0.32105146,10,3,,,,,,,,,3.00E-48,CHOYP_TTC8.1.1,,,,,,,,, comp114091_c0_seq1,380,39.4737,0.76464678,11,15,,5.00E-06,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp114095_c0_seq1,214,46.729,0.78183525,2,7,,2.00E-13,Q5R8X6,"Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Plasmin heavy chain A, short form; Plasmin light chain B]","Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Plasmin heavy chain A, short form; Plasmin light chain B]",GO:0007596; GO:0005576; GO:0042730; GO:0006508; GO:0004252; GO:0048771,blood coagulation; extracellular region; fibrinolysis; proteolysis; serine-type endopeptidase activity; tissue remodeling,PF00051;PF00024;PF00089;,,,,,,,,,PLMN_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; tissue remodeling [GO:0048771] comp114097_c0_seq1,355,47.0423,0.35846084,15,5,,3.00E-20,P07314,Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain],Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain],GO:0007568; GO:0034599; GO:0005615; GO:0003840; GO:0006536; GO:0006750; GO:0006751; GO:0036374; GO:0005887; GO:0031179; GO:0032355; GO:0032496; GO:0034612,aging; cellular response to oxidative stress; extracellular space; gamma-glutamyltransferase activity; glutamate metabolic process; glutathione biosynthetic process; glutathione catabolic process; glutathione hydrolase activity; integral to plasma membrane; peptide modification; response to estradiol stimulus; response to lipopolysaccharide; response to tumor necrosis factor,PF01019;,,,,,,,,,GGT1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; peptide modification [GO:0031179]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; zymogen activation [GO:0031638] comp114110_c1_seq2,473,47.3573,0.46064346,3,0,,,,,,,,,4.00E-24,CHOYP_CNTRL.1.1,,,,,,,,, comp114110_c1_seq3,381,46.1942,0.66046472,2,0,,,,,,,,,3.00E-24,CHOYP_CNTRL.1.1,,,,,,,,, comp114114_c0_seq1,223,48.8789,0.68155529,5,30,,7.00E-07,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp114118_c0_seq1,926,39.7408,0.71877693,25,94,,6.00E-10,Q14995,Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R),Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb alpha-related receptor) (RVR) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R),GO:0004879; GO:0005654; GO:0043565; GO:0003707; GO:0006367; GO:0008270,ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleoplasm; sequence-specific DNA binding; steroid hormone receptor activity; transcription initiation from RNA polymerase II promoter; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR1D2_HUMAN,Homo sapiens (Human),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp114123_c0_seq1,643,33.126,0.56991288,104,29,,6.00E-07,Q8AVY1,Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3),Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3),GO:0005737,cytoplasm,PF07004;,,,,,,,,,ODF3A_XENLA,Xenopus laevis (African clawed frog), comp114128_c1_seq1,512,47.8516,0.3420013,18,0,,2.00E-22,Q62956,Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)],Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)],GO:0005524; GO:0061026; GO:0005901; GO:0021551; GO:0005737; GO:0009880; GO:0007507; GO:0016021; GO:0007595; GO:0060749; GO:0060644; GO:0043653; GO:0005739; GO:0008285; GO:0010656; GO:0001755; GO:0005634; GO:0042476; GO:0021889; GO:0070374; GO:2000366; GO:0060045; GO:0030335; GO:0050679; GO:0046326; GO:0043552; GO:0032230; GO:0045893; GO:0042523; GO:0014069; GO:0046777; GO:0004716; GO:0042493; GO:0042542; GO:0032570; GO:0023014; GO:0043129; GO:0060074; GO:0006351; GO:0004714; GO:0007169,"ATP binding; cardiac muscle tissue regeneration; caveola; central nervous system morphogenesis; cytoplasm; embryonic pattern specification; heart development; integral to membrane; lactation; mammary gland alveolus development; mammary gland epithelial cell differentiation; mitochondrial fragmentation involved in apoptotic process; mitochondrion; negative regulation of cell proliferation; negative regulation of muscle cell apoptotic process; neural crest cell migration; nucleus; odontogenesis; olfactory bulb interneuron differentiation; positive regulation of ERK1 and ERK2 cascade; positive regulation of STAT protein import into nucleus; positive regulation of cardiac muscle cell proliferation; positive regulation of cell migration; positive regulation of epithelial cell proliferation; positive regulation of glucose import; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of synaptic transmission, GABAergic; positive regulation of transcription, DNA-dependent; positive regulation of tyrosine phosphorylation of Stat5 protein; postsynaptic density; protein autophosphorylation; receptor signaling protein tyrosine kinase activity; response to drug; response to hydrogen peroxide; response to progesterone stimulus; signal transduction by phosphorylation; surfactant homeostasis; synapse maturation; transcription, DNA-dependent; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway",PF00757;PF14843;PF07714;PF01030;,,,,,,,,,ERBB4_RAT,Rattus norvegicus (Rat),"cardiac muscle tissue regeneration [GO:0061026]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; mammary gland development [GO:0030879]; mammary gland epithelial cell differentiation [GO:0060644]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; odontogenesis [GO:0042476]; olfactory bulb interneuron differentiation [GO:0021889]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of STAT protein import into nucleus [GO:2000366]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of Stat5 protein [GO:0042523]; protein autophosphorylation [GO:0046777]; regulation of cell migration [GO:0030334]; response to drug [GO:0042493]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; surfactant homeostasis [GO:0043129]; synapse maturation [GO:0060074]; telencephalon development [GO:0021537]; transcription, DNA-templated [GO:0006351]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" comp114128_c2_seq1,648,47.9938,0.34973554,32,23,,1.00E-27,P0CY46,Epidermal growth factor receptor (Egfr) (EC 2.7.10.1),Epidermal growth factor receptor (Egfr) (EC 2.7.10.1),GO:0005524; GO:0016021; GO:0007275; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00757;PF14843;PF07714;PF01030;,,,,,,,,,EGFR_APIME,Apis mellifera (Honeybee),multicellular organism development [GO:0007275]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp114133_c0_seq2,291,41.5808,0.56154509,3,0,,,,,,,,,1.00E-20,CHOYP_LOC100117425.1.1,,,,,,,,, comp114135_c0_seq1,425,44.2353,0.48233963,13,18,,2.00E-34,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp114135_c1_seq1,274,44.8905,0.21814146,4,4,,7.00E-07,O75074,Low-density lipoprotein receptor-related protein 3 (LRP-3) (105 kDa low-density lipoprotein receptor-related protein) (hLRp105),Low-density lipoprotein receptor-related protein 3 (LRP-3) (105 kDa low-density lipoprotein receptor-related protein) (hLRp105),GO:0005905; GO:0016021; GO:0006898,coated pit; integral to membrane; receptor-mediated endocytosis,PF00431;PF00057;,,,,,,,,,LRP3_HUMAN,Homo sapiens (Human),receptor-mediated endocytosis [GO:0006898] comp114144_c0_seq1,459,47.9303,0.68634278,27,73,,2.00E-41,Q641Z2,Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48),Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48),GO:0005737; GO:0004725,cytoplasm; protein tyrosine phosphatase activity,PF00650;PF00102;,2.00E-22,CHOYP_LOC100883586.1.1,,,,,,,PTN9_RAT,Rattus norvegicus (Rat), comp114147_c0_seq1,233,41.2017,0.91407934,11,13,,5.00E-11,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp114148_c0_seq1,988,40.4858,0.55124072,96,11,,6.00E-63,Q05973,Sodium channel protein 1 brain (Sodium channel protein I brain),Sodium channel protein 1 brain (Sodium channel protein I brain),GO:0035725; GO:0005248; GO:0001518,sodium ion transmembrane transport; voltage-gated sodium channel activity; voltage-gated sodium channel complex,PF16905;PF00520;,9.00E-74,CHOYP_SCN1.2.2,,,,,,,SCN1_LOLBL,Heterololigo bleekeri (Spear squid) (Loligo bleekeri), comp114151_c0_seq1,495,43.2323,0.5302944,8,10,,3.00E-31,Q90ZB9,StAR-related lipid transfer protein 3 (MLN64-like protein) (START domain-containing protein 3) (StARD3) (Fragment),StAR-related lipid transfer protein 3 (MLN64-like protein) (START domain-containing protein 3) (StARD3) (Fragment),GO:0015485; GO:0030301; GO:0017127; GO:0006694,cholesterol binding; cholesterol transport; cholesterol transporter activity; steroid biosynthetic process,PF01852;,1.00E-12,CHOYP_STAR.2.4,,,,,,,STAR3_SALFO,Salvelinus fontinalis (Brook trout) (Salmo fontinalis),lipid transport [GO:0006869]; steroid biosynthetic process [GO:0006694] comp114164_c0_seq2,610,41.1475,0.23472979,26,11,,1.00E-15,Q5REW9,Ankyrin repeat domain-containing protein 27,Ankyrin repeat domain-containing protein 27,GO:0005096; GO:0005737; GO:0043547,GTPase activator activity; cytoplasm; positive regulation of GTPase activity,PF12796;PF02204;,,,,,,,,,ANR27_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp114184_c0_seq1,578,42.2145,0.62447103,23,9,,6.00E-32,Q6TEP1,Protein FAM91A1,Protein FAM91A1,,,PF14648;PF14647;,4.00E-18,CHOYP_F91A1.1.1,,,,,,,F91A1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp114189_c1_seq1,393,44.5293,0.30999414,4,13,,2.00E-14,Q7Z7G8,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp114192_c0_seq1,972,43.107,0.36344998,25,105,,1.00E-151,Q5R9E1,"Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)","Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)",GO:0004419; GO:0046951; GO:0046872; GO:0005759; GO:0005777,hydroxymethylglutaryl-CoA lyase activity; ketone body biosynthetic process; metal ion binding; mitochondrial matrix; peroxisome,PF00682;,3.00E-118,CHOYP_LOC100710578.1.1,,,,,,,HMGCL_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ketone body biosynthetic process [GO:0046951] comp114195_c1_seq3,488,44.6721,0.87492912,9,5,,2.00E-23,Q9D939,Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-),Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-),GO:0005764; GO:0008146,lysosome; sulfotransferase activity,PF00685;,,,,,,,,,ST1C2_MOUSE,Mus musculus (Mouse),sulfation [GO:0051923] comp114204_c3_seq1,269,44.6097,0.45621582,0,0,,8.00E-15,Q54DS4,WD repeat-containing protein DDB_G0292056,WD repeat-containing protein DDB_G0292056,,,,,,,,,,,,Y2056_DICDI,Dictyostelium discoideum (Slime mold), comp114204_c3_seq2,682,43.695,0.53074119,16,21,,2.00E-28,Q6PJI9,WD repeat-containing protein 59,WD repeat-containing protein 59,,,PF00400;,,,,,,,,,WDR59_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008] comp114220_c0_seq2,447,42.5056,0.96410042,0,20,,4.00E-22,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp114220_c1_seq1,227,47.1366,0.72459033,2,25,,6.00E-09,P25304,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0005605; GO:0005509; GO:0030154; GO:0030054; GO:0035374; GO:0002162; GO:0043395; GO:0016021; GO:0007528; GO:0005886; GO:0032321; GO:0051491; GO:0045887; GO:0045944; GO:0043113; GO:0001932; GO:0033691; GO:0045202; GO:0007416,basal lamina; calcium ion binding; cell differentiation; cell junction; chondroitin sulfate binding; dystroglycan binding; heparan sulfate proteoglycan binding; integral to membrane; neuromuscular junction development; plasma membrane; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; regulation of protein phosphorylation; sialic acid binding; synapse; synapse assembly,PF00008;PF00050;PF07648;PF00053;PF00054;PF01390;,,,,,,,,,AGRIN_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotetramerization [GO:0051290]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416] comp114220_c2_seq1,422,49.5261,0.65852018,15,23,,1.00E-08,Q6DI48,Delta-like protein A (DeltaA),Delta-like protein A (DeltaA),GO:0007219; GO:0001525; GO:0005509; GO:0030154; GO:0016021; GO:0007399,Notch signaling pathway; angiogenesis; calcium ion binding; cell differentiation; integral to membrane; nervous system development,PF01414;PF00008;PF07657;,,,,,,,,,DLLA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525]; diencephalon development [GO:0021536]; embryonic pattern specification [GO:0009880]; floor plate development [GO:0033504]; hypochord development [GO:0055016]; inner ear receptor cell differentiation [GO:0060113]; midbrain development [GO:0030901]; neural crest cell development [GO:0014032]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; notochord cell differentiation [GO:0060034]; regulation of Notch signaling pathway [GO:0008593]; ventral spinal cord interneuron differentiation [GO:0021514] comp114224_c0_seq1,284,45.7746,0.62500775,1,0,,,,,,,,,2.00E-17,CHOYP_LOC579367.1.1,,,,,,,,, comp114224_c0_seq2,304,45.3947,0.65171645,0,0,,5.00E-08,A2VCL2,Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene),Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene),,,,,,,,,,,,CC162_HUMAN,Homo sapiens (Human), comp114229_c1_seq1,432,47.4537,0.29217431,8,5,,2.00E-43,Q2LD37,Uncharacterized protein KIAA1109 (Fragile site-associated protein),Uncharacterized protein KIAA1109 (Fragile site-associated protein),GO:0016021; GO:0016020; GO:0005634; GO:0001558; GO:0030856,integral to membrane; membrane; nucleus; regulation of cell growth; regulation of epithelial cell differentiation,PF10479;,1.00E-55,CHOYP_K1109.1.1,,,,,,,K1109_HUMAN,Homo sapiens (Human),regulation of cell growth [GO:0001558]; regulation of epithelial cell differentiation [GO:0030856] comp114230_c0_seq1,446,36.7713,1.00288966,14,73,,,,,,,,,1.00E-11,CHOYP_INF2.1.5,,,,,,,,, comp114239_c0_seq1,398,45.4774,0.3415282,28,7,,5.00E-65,Q13472,DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha),DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0016605; GO:0005694; GO:0007126; GO:0008270,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; PML body; chromosome; meiosis; zinc ion binding,PF01131;PF01751;PF01396;PF06839;,2.00E-40,CHOYP_TOP3A.1.2,,,,,,,TOP3A_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA topological change [GO:0006265]; meiotic nuclear division [GO:0007126]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732] comp114240_c0_seq1,651,44.086,0.38162221,8,35,,3.00E-44,Q1EG27,Myosin-IIIb (EC 2.7.11.1),Myosin-IIIb (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0032433; GO:0000146; GO:0016459; GO:0018105; GO:0018107; GO:0001917; GO:0001750; GO:0051491; GO:0046777; GO:0004674; GO:0050896; GO:0032426; GO:0007601,ATP binding; cytoplasm; filopodium tip; microfilament motor activity; myosin complex; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; photoreceptor inner segment; photoreceptor outer segment; positive regulation of filopodium assembly; protein autophosphorylation; protein serine/threonine kinase activity; response to stimulus; stereocilium bundle tip; visual perception,PF00612;PF00063;PF00069;,5.00E-62,CHOYP_MYO3AL.1.1,,,,,,,MYO3B_MOUSE,Mus musculus (Mouse),peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp114255_c1_seq2,1021,44.4662,0.63498042,39,20,,4.00E-13,Q6PJG2,ELM2 and SANT domain-containing protein 1,ELM2 and SANT domain-containing protein 1 (MIDEAS),GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01448;,,,,,,,,,CN043_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp114278_c0_seq1,515,48.7379,0.75448473,7,34,,2.00E-56,Q6NSJ0,Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-),Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-),GO:0005975; GO:0004553; GO:0016021; GO:0031965; GO:0043568; GO:0051897; GO:0048741,"carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; integral to membrane; nuclear membrane; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of protein kinase B signaling cascade; skeletal muscle fiber development",PF01055;,,,,,,,,,K1161_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; skeletal muscle fiber development [GO:0048741] comp114295_c0_seq1,1101,42.416,0.72859564,82,14,,,,,,,,,5.00E-59,CHOYP_contig_039791,,,,,,,,, comp114304_c0_seq1,399,41.3534,0.71685038,16,0,,9.00E-33,P40818,Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),GO:0007265; GO:0001669; GO:0008283; GO:0004197; GO:0005829; GO:0005769; GO:0010008; GO:0007032; GO:0019897; GO:0030496; GO:0000281; GO:0005634; GO:0071108; GO:0070536; GO:0004221; GO:0006511; GO:0004843,Ras protein signal transduction; acrosomal vesicle; cell proliferation; cysteine-type endopeptidase activity; cytosol; early endosome; endosome membrane; endosome organization; extrinsic to plasma membrane; midbody; mitotic cytokinesis; nucleus; protein K48-linked deubiquitination; protein K63-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00581;PF00443;PF08969;,2.00E-14,CHOYP_LOC100367006.2.2,,,,,,,UBP8_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; endosome organization [GO:0007032]; ERBB2 signaling pathway [GO:0038128]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent protein catabolic process [GO:0006511] comp114326_c0_seq1,236,37.7119,0.12092054,8,11,,5.00E-38,Q6PE18,Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha),Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha),GO:0004430; GO:0035651; GO:0005524; GO:0030054; GO:0016023; GO:0031410; GO:0030425; GO:0005768; GO:0035838; GO:0044231; GO:0045121; GO:0005739; GO:0043025; GO:0042734,1-phosphatidylinositol 4-kinase activity; AP-3 adaptor complex binding; ATP binding; cell junction; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; dendrite; endosome; growing cell tip; host cell presynaptic membrane; membrane raft; mitochondrion; neuronal cell body; presynaptic membrane,PF00454;,3.00E-46,CHOYP_LOC655570.1.2,,,,,,,P4K2A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854] comp114329_c0_seq1,918,38.4532,0.56289557,23,86,,3.00E-08,Q5BKU9,Oxidoreductase-like domain-containing protein 1,Oxidoreductase-like domain-containing protein 1,GO:0005739,mitochondrion,PF09791;,8.00E-11,CHOYP_PHUM_PHUM344520.1.1,,,,,,,OXLD1_HUMAN,Homo sapiens (Human), comp114337_c0_seq1,360,44.1667,1.22989268,0,17,,8.00E-25,Q66IC8,Tctex1 domain-containing protein 1,Tctex1 domain-containing protein 1,,,PF03645;,4.00E-16,CHOYP_LOC100371143.1.1,,,,,,,TC1D1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp114340_c0_seq1,1072,42.8172,0.40829564,9,5,,6.00E-32,Q9VFB7,Trafficking protein particle complex subunit 10 (Shal Interactor of Di-Leucine Motif) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),Trafficking protein particle complex subunit 10 (Shal Interactor of Di-Leucine Motif) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),GO:0005794; GO:0030425; GO:0043204; GO:0016192,Golgi apparatus; dendrite; perikaryon; vesicle-mediated transport,PF12584;,,,,,,,,,TPC10_DROME,Drosophila melanogaster (Fruit fly),early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087] comp114364_c0_seq1,844,45.0237,0.58793325,16,49,,4.00E-17,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp114364_c1_seq1,287,43.2056,0.52941819,0,24,,3.00E-09,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp114370_c0_seq1,661,37.2163,0.36274056,15,34,,7.00E-30,Q86BS6,Methyltransferase-like protein (EC 2.1.1.-),Methyltransferase-like protein (EC 2.1.1.-),GO:0008757,S-adenosylmethionine-dependent methyltransferase activity,,4.00E-32,CHOYP_METTL6.1.1,,,,,,,METL_DROME,Drosophila melanogaster (Fruit fly), comp114370_c1_seq1,581,41.6523,0.52846423,25,34,,3.00E-54,Q8TCB7,Methyltransferase-like protein 6 (EC 2.1.1.-),Methyltransferase-like protein 6 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF08242;,2.00E-21,CHOYP_METTL6.1.1,,,,,,,METL6_HUMAN,Homo sapiens (Human), comp114378_c0_seq1,350,40.2857,0.53090321,5,8,,2.00E-07,P21941,Cartilage matrix protein (Matrilin-1),Cartilage matrix protein (Matrilin-1),GO:0030198; GO:0005201; GO:0003429; GO:0006461; GO:0005578; GO:0030500,extracellular matrix organization; extracellular matrix structural constituent; growth plate cartilage chondrocyte morphogenesis; protein complex assembly; proteinaceous extracellular matrix; regulation of bone mineralization,PF10393;PF00092;,,,,,,,,,MATN1_HUMAN,Homo sapiens (Human),extracellular matrix organization [GO:0030198]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; protein complex assembly [GO:0006461]; regulation of bone mineralization [GO:0030500] comp114379_c0_seq2,938,40.9382,0.30569758,29,95,,2.00E-16,Q80TY5,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp114381_c0_seq1,898,36.637,0.20068482,258,843,,8.00E-47,Q9UH36,SRR1-like protein (SRR1 domain-containing protein),SRR1-like protein (SRR1 domain-containing protein),GO:0048511,rhythmic process,PF07985;,,,,,,,,,SRR1L_HUMAN,Homo sapiens (Human),rhythmic process [GO:0048511] comp114387_c2_seq1,503,41.3519,1.04142423,10,59,,3.00E-42,P30122,Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),GO:0047372; GO:0004091; GO:0005829; GO:0005615; GO:0016042; GO:0004771; GO:0004806,acylglycerol lipase activity; carboxylesterase activity; cytosol; extracellular space; lipid catabolic process; sterol esterase activity; triglyceride lipase activity,PF00135;,,,,,,,,,CEL_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp114390_c0_seq1,622,43.0868,0.62676218,29,34,,3.00E-33,O89110,Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10],Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10],GO:0030690; GO:0006919; GO:0001525; GO:0071260; GO:0005813; GO:0097153; GO:0031264; GO:0008625; GO:0007507; GO:0097284; GO:0030225; GO:0005739; GO:0043124; GO:0060546; GO:0001841; GO:0043123; GO:2001238; GO:0045651; GO:0045862; GO:0051603; GO:0070243; GO:0034612,Noc1p-Noc2p complex; activation of cysteine-type endopeptidase activity involved in apoptotic process; angiogenesis; cellular response to mechanical stimulus; centrosome; cysteine-type endopeptidase activity involved in apoptotic process; death-inducing signaling complex; extrinsic apoptotic signaling pathway via death domain receptors; heart development; hepatocyte apoptotic process; macrophage differentiation; mitochondrion; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of necroptosis; neural tube formation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of macrophage differentiation; positive regulation of proteolysis; proteolysis involved in cellular protein catabolic process; regulation of thymocyte apoptotic process; response to tumor necrosis factor,PF01335;,,,,,,,,,CASP8_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of thymocyte apoptotic process [GO:0070243]; response to tumor necrosis factor [GO:0034612]; TRAIL-activated apoptotic signaling pathway [GO:0036462] comp114393_c1_seq1,757,42.5363,1.03370529,0,0,,,,,,,,,5.00E-12,CHOYP_BRAFLDRAFT_102685.1.1,,,,,,,,, comp114393_c1_seq2,1879,44.7578,0.96184164,0,21,,2.00E-07,O24581,Luminal-binding protein 3 (BiP3),Luminal-binding protein 3 (BiP3),GO:0005524; GO:0005788,ATP binding; endoplasmic reticulum lumen,PF00012;,,,,,,,,,BIP3_MAIZE,Zea mays (Maize), comp114393_c1_seq3,1783,44.4195,0.98396003,0,0,,2.00E-76,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp114397_c0_seq1,808,39.3564,0.57609773,31,33,,3.00E-21,Q68F62,Mpv17-like protein,Mpv17-like protein,GO:0016021; GO:0005778,integral to membrane; peroxisomal membrane,PF04117;,,,,,,,,,MP17L_XENLA,Xenopus laevis (African clawed frog), comp114410_c1_seq1,1163,42.9063,0.46762046,53,35,,8.00E-65,Q8N9N5,Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein),Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein),GO:0003677; GO:0007049; GO:0016568; GO:0007275; GO:0042177; GO:0005634; GO:0034504; GO:0006355; GO:0006351,"DNA binding; cell cycle; chromatin modification; multicellular organismal development; negative regulation of protein catabolic process; nucleus; protein localization to nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10523;,5.00E-65,CHOYP_LOC100376508.1.1,,,,,,,BANP_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; chromatin modification [GO:0016568]; multicellular organism development [GO:0007275]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to nucleus [GO:0034504]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp114412_c0_seq2,827,42.2007,0.81512781,29,232,,5.00E-70,Q91X52,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0016324; GO:0005903; GO:0005881; GO:0006006; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; apical plasma membrane; brush border; cytoplasmic microtubule; glucose metabolic process; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,2.00E-72,ruditapes2_c2560,,,,,DCXR_MOUSE,Mus musculus (Mouse),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp114414_c0_seq1,500,44.8,0.6784623,16,16,,1.00E-63,P18106,Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer),Tyrosine-protein kinase Fer (EC 2.7.10.2),GO:0005524; GO:0051017; GO:0005912; GO:0007411; GO:0046664; GO:0007394; GO:0004715; GO:0005886; GO:0004713,"ATP binding; actin filament bundle assembly; adherens junction; axon guidance; dorsal closure, amnioserosa morphology change; dorsal closure, elongation of leading edge cells; non-membrane spanning protein tyrosine kinase activity; plasma membrane; protein tyrosine kinase activity",PF00611;PF07714;PF00017;,4.00E-56,CHOYP_LOC100119086.1.1,,,,,,,FPS_DROME,Drosophila melanogaster (Fruit fly),"actin filament bundle assembly [GO:0051017]; axon guidance [GO:0007411]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; photoreceptor cell morphogenesis [GO:0008594]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" comp114414_c1_seq1,361,47.3684,0.74711635,6,17,,5.00E-30,Q95KR7,Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK),Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK),GO:0005524; GO:0042169; GO:0030217; GO:0006919; GO:0006882; GO:0045121; GO:0004715; GO:0000242; GO:0005886; GO:0050870; GO:2001244; GO:0004722; GO:0004713; GO:0042493,ATP binding; SH2 domain binding; T cell differentiation; activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular zinc ion homeostasis; membrane raft; non-membrane spanning protein tyrosine kinase activity; pericentriolar material; plasma membrane; positive regulation of T cell activation; positive regulation of intrinsic apoptotic signaling pathway; protein serine/threonine phosphatase activity; protein tyrosine kinase activity; response to drug,PF07714;PF00017;PF00018;,7.00E-13,CHOYP_FERT2.1.1,,,,,,,LCK_SAISC,Saimiri sciureus (Common squirrel monkey),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular zinc ion homeostasis [GO:0006882]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of T cell activation [GO:0050870]; response to drug [GO:0042493]; T cell differentiation [GO:0030217] comp114414_c2_seq1,337,47.181,0.48179075,9,21,,8.00E-12,P98077,SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2),SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2),GO:0007265; GO:0005829; GO:0008286; GO:0048011,Ras protein signal transduction; cytosol; insulin receptor signaling pathway; neurotrophin TRK receptor signaling pathway,PF00640;PF00017;,,,,,,,,,SHC2_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; MAPK cascade [GO:0000165]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp114424_c1_seq2,730,42.7397,0.28936543,6,31,,2.00E-41,A2VD33,Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase),Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase),GO:0006777; GO:0008265; GO:0030151; GO:0043545; GO:0030170; GO:0016740,Mo-molybdopterin cofactor biosynthetic process; Mo-molybdopterin cofactor sulfurase activity; molybdenum ion binding; molybdopterin cofactor metabolic process; pyridoxal phosphate binding; transferase activity,PF00266;PF03473;PF03476;,,,,,,,,,MOCOS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),molybdopterin cofactor metabolic process [GO:0043545]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp114433_c0_seq1,895,39.8883,0.55761616,33,111,,1.00E-10,Q09884,Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)],Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)],GO:0005524; GO:0016442; GO:0007049; GO:0034613; GO:0031048; GO:0007059; GO:0033562; GO:0005829; GO:0003690; GO:0003725; GO:0035389; GO:1990188; GO:0004386; GO:0031618; GO:0005719; GO:0034399; GO:0005643; GO:0030422; GO:0090052; GO:0051570; GO:0004525; GO:0004540; GO:0008270,ATP binding; RISC complex; cell cycle; cellular protein localization; chromatin silencing by small RNA; chromosome segregation; co-transcriptional gene silencing by RNA interference machinery; cytosol; double-stranded DNA binding; double-stranded RNA binding; establishment of chromatin silencing at silent mating-type cassette; euchromatin binding; helicase activity; nuclear centromeric heterochromatin; nuclear euchromatin; nuclear periphery; nuclear pore; production of siRNA involved in RNA interference; regulation of chromatin silencing at centromere; regulation of histone H3-K9 methylation; ribonuclease III activity; ribonuclease activity; zinc ion binding,PF03368;PF00271;PF04851;PF00636;,4.00E-14,CHOYP_HELF.1.1,,,,,,,DCR1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell cycle [GO:0007049]; cellular protein localization [GO:0034613]; chromatin silencing at centromere outer repeat region [GO:1990141]; chromatin silencing by small RNA [GO:0031048]; chromosome segregation [GO:0007059]; co-transcriptional gene silencing by RNA interference machinery [GO:0033562]; establishment of chromatin silencing at silent mating-type cassette [GO:0035389]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of gene expression [GO:0010629]; positive regulation of termination of RNA polymerase II transcription [GO:1904595]; production of siRNA involved in RNA interference [GO:0030422]; regulation of chromatin silencing at centromere [GO:0090052]; regulation of histone H3-K9 methylation [GO:0051570]; RNA processing [GO:0006396] comp114435_c0_seq1,1646,47.2661,0.51253396,0,0,,4.00E-09,Q8ST83,Polycomb protein PHO (Protein pleiohomeotic) (Transcription factor YY1 homolog),Polycomb protein PHO (Protein pleiohomeotic) (Transcription factor YY1 homolog),GO:0006310; GO:0006281; GO:0006265; GO:0031011; GO:0000980; GO:0031490; GO:0006342; GO:0048096; GO:0046872; GO:0007275; GO:0005704; GO:0005703; GO:0006351,"DNA recombination; DNA repair; DNA topological change; Ino80 complex; RNA polymerase II distal enhancer sequence-specific DNA binding; chromatin DNA binding; chromatin silencing; chromatin-mediated maintenance of transcription; metal ion binding; multicellular organismal development; polytene chromosome band; polytene chromosome puff; transcription, DNA-dependent",,,,,,,,,,PHO_DROME,Drosophila melanogaster (Fruit fly),"chromatin-mediated maintenance of transcription [GO:0048096]; chromatin remodeling [GO:0006338]; chromatin silencing [GO:0006342]; dendrite morphogenesis [GO:0048813]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; gene silencing [GO:0016458]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp114435_c0_seq2,1634,47.3684,0.51420274,0,0,,2.00E-11,Q5R4K8,Zinc finger protein 615,Zinc finger protein 615,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN615_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp114435_c0_seq3,871,49.2537,0.53345056,0,0,,9.00E-47,G5EBU4,Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),GO:0007411; GO:0046872; GO:0000122; GO:0005634; GO:0045773; GO:0043565; GO:0003700; GO:0006351,"axon guidance; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of axon extension; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF13912;,7.00E-56,CHOYP_PHUM_PHUM017930.1.1,,,,,,,ZAG1_CAEEL,Caenorhabditis elegans,"axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]" comp114435_c0_seq4,883,49.0374,0.53045373,0,0,,1.00E-38,Q9R0G7,Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b),Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b),GO:0070412; GO:0021846; GO:0005737; GO:0021766; GO:0046872; GO:0001755; GO:0001843; GO:0005730; GO:0043507; GO:0030177; GO:0043565; GO:0003700; GO:0001756; GO:0006351,"R-SMAD binding; cell proliferation in forebrain; cytoplasm; hippocampus development; metal ion binding; neural crest cell migration; neural tube closure; nucleolus; positive regulation of JUN kinase activity; positive regulation of Wnt receptor signaling pathway; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; somitogenesis; transcription, DNA-dependent",PF05605;,,,,,,,,,ZEB2_MOUSE,Mus musculus (Mouse),cell proliferation in forebrain [GO:0021846]; central nervous system development [GO:0007417]; collateral sprouting [GO:0048668]; corpus callosum morphogenesis [GO:0021540]; corticospinal tract morphogenesis [GO:0021957]; developmental pigmentation [GO:0048066]; embryonic morphogenesis [GO:0048598]; hippocampus development [GO:0021766]; mammillary axonal complex development [GO:0061373]; melanocyte migration [GO:0097324]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lens fiber cell differentiation [GO:1902748]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of melanosome organization [GO:1903056]; somitogenesis [GO:0001756] comp114436_c0_seq2,1802,45.727,0.52182789,13,0,,2.00E-30,Q811L6,Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1),Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0000287; GO:0004674,ATP binding; cytoplasm; magnesium ion binding; protein serine/threonine kinase activity,PF08926;PF00595;PF00069;,,,,,,,,,MAST4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] comp114442_c0_seq1,647,44.204,0.63454911,8,31,,2.00E-14,Q5ZIT9,Major facilitator superfamily domain-containing protein 1,Major facilitator superfamily domain-containing protein 1,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,2.00E-68,CHOYP_BRAFLDRAFT_128311.2.2,,,,,,,MFSD1_CHICK,Gallus gallus (Chicken),transmembrane transport [GO:0055085] comp114444_c0_seq1,670,45.5224,0.49062475,37,14,,1.00E-31,P23708,Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA),Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA),GO:0016602; GO:0003677; GO:0005654; GO:2000648; GO:0045944; GO:2000036; GO:0003700; GO:0006351,"CCAAT-binding factor complex; DNA binding; nucleoplasm; positive regulation of stem cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of stem cell maintenance; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02045;,3.00E-20,CHOYP_LOC100906398.1.1,,,,,,,NFYA_MOUSE,Mus musculus (Mouse),"positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]" comp114452_c0_seq1,511,40.5088,0.74927116,0,4,,4.00E-08,Q86Z23,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_HUMAN,Homo sapiens (Human),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp114452_c0_seq2,457,40.0438,0.61725363,0,0,,4.00E-07,Q6UW01,Cerebellin-3,Cerebellin-3,GO:0005794; GO:0030054; GO:0005783; GO:0005615; GO:0045202,Golgi apparatus; cell junction; endoplasmic reticulum; extracellular space; synapse,PF00386;,,,,,,,,,CBLN3_HUMAN,Homo sapiens (Human), comp114477_c1_seq1,511,38.3562,0.54122829,10,35,,1.00E-35,Q6DRM0,Tail-anchored protein insertion receptor WRB (Tryptophan-rich basic protein) (WRB),Tail-anchored protein insertion receptor WRB (Tryptophan-rich basic protein) (WRB),GO:0005789; GO:0007507; GO:0016021; GO:0060041,endoplasmic reticulum membrane; heart development; integral to membrane; retina development in camera-type eye,PF04420;,,,,,,,,,WRB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),heart development [GO:0007507]; retina development in camera-type eye [GO:0060041]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] comp114478_c0_seq1,456,46.9298,0.4478817,17,0,,6.00E-10,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp114495_c0_seq1,661,42.5113,0.50642711,4,82,,4.00E-53,Q86WZ6,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp114495_c1_seq1,392,39.0306,0.40376975,17,60,,5.00E-31,Q24732,Protein glass,Protein glass,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0050896; GO:0006351; GO:0007601,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; response to stimulus; transcription, DNA-dependent; visual perception",PF00096;,,,,,,,,,GLAS_DROVI,Drosophila virilis (Fruit fly),"regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp114497_c0_seq1,1082,41.7745,0.73136496,48,45,,2.00E-57,Q8IWX5,Sphingosine-1-phosphate phosphatase 2 (SPPase2) (Spp2) (hSPP2) (EC 3.1.3.-) (Sphingosine-1-phosphatase 2),Sphingosine-1-phosphate phosphatase 2 (SPPase2) (Spp2) (hSPP2) (EC 3.1.3.-) (Sphingosine-1-phosphatase 2),GO:0005789; GO:0016021; GO:0030148; GO:0006670; GO:0042392,endoplasmic reticulum membrane; integral to membrane; sphingolipid biosynthetic process; sphingosine metabolic process; sphingosine-1-phosphate phosphatase activity,PF01569;,,,,,,,,,SGPP2_HUMAN,Homo sapiens (Human),sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670] comp114499_c0_seq1,1142,43.6077,0.68343621,30,85,,1.00E-13,P42664,Embryonic protein UVS.2 (EC 3.4.24.-),Embryonic protein UVS.2 (EC 3.4.24.-),GO:0004222; GO:0006508; GO:0008270,metalloendopeptidase activity; proteolysis; zinc ion binding,PF01400;PF00431;,,,,,,,,,UVS2_XENLA,Xenopus laevis (African clawed frog), comp114507_c0_seq1,555,39.4595,0.83609294,22,19,,4.00E-30,A2BFP5,Solute carrier family 12 member 9,Solute carrier family 12 member 9,GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF00324;PF03522;,2.00E-27,CHOYP_S12A9.1.1,,,,,,,S12A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp114509_c0_seq1,661,44.4781,0.4595318,25,34,,1.00E-40,Q7SY48,HEAT repeat-containing protein 1 (Protein BAP28),HEAT repeat-containing protein 1 (Protein BAP28),GO:0000462; GO:0043066; GO:0005730; GO:0043487; GO:0030529,"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of apoptotic process; nucleolus; regulation of RNA stability; ribonucleoprotein complex",PF08146;PF12397;,,,,,,,,,HEAT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; regulation of RNA stability [GO:0043487]" comp114513_c0_seq4,618,42.0712,0.22165253,2,0,,2.00E-35,Q8R5L3,Vam6/Vps39-like protein,Vam6/Vps39-like protein,GO:0006886; GO:0031902; GO:0005765; GO:0005083; GO:0016192,intracellular protein transport; late endosome membrane; lysosomal membrane; small GTPase regulator activity; vesicle-mediated transport,PF00637;PF00780;PF10366;PF10367;,,,,,,,,,VPS39_MOUSE,Mus musculus (Mouse),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]; vesicle-mediated transport [GO:0016192]" comp114516_c2_seq1,268,44.0299,0.31234107,6,8,,6.00E-21,Q29449,Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II),Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II),GO:0005524; GO:0019829; GO:0042584; GO:0005783; GO:0016021; GO:0000287; GO:0004012; GO:0005886,ATP binding; cation-transporting ATPase activity; chromaffin granule membrane; endoplasmic reticulum; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity; plasma membrane,PF00122;PF16212;PF16209;,2.00E-25,CHOYP_AT8A1.2.2,,,,,,,AT8A1_BOVIN,Bos taurus (Bovine),Golgi vesicle budding [GO:0048194] comp114524_c0_seq1,578,43.0796,0.41384139,11,65,,1.00E-47,Q15477,Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP),Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP),GO:0005524; GO:0004004; GO:0003723; GO:0055087; GO:0005634,ATP binding; ATP-dependent RNA helicase activity; RNA binding; Ski complex; nucleus,PF00270;PF08148;PF00271;PF13234;,2.00E-53,CHOYP_SKIV2L.4.4,,,,,,,SKIV2_HUMAN,Homo sapiens (Human),RNA catabolic process [GO:0006401] comp114528_c0_seq1,851,40.8931,0.48480453,16,71,,8.00E-18,P79701,Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Endothelial kinase receptor EK2) (Quek 2) (Quek2),Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Endothelial kinase receptor EK2) (Quek 2) (Quek2),GO:0005524; GO:0001525; GO:0030154; GO:0005887; GO:0018108; GO:0048010; GO:0038084; GO:0005021,ATP binding; angiogenesis; cell differentiation; integral to plasma membrane; peptidyl-tyrosine phosphorylation; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor signaling pathway; vascular endothelial growth factor-activated receptor activity,PF07679;PF07714;,,,,,,,,,VGFR3_COTCO,Coturnix coturnix (Common quail) (Tetrao coturnix),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp114528_c1_seq1,554,38.2671,0.5433446,10,10,,2.00E-09,Q8JFR5,Mast/stem cell growth factor receptor kita (SCFR) (EC 2.7.10.1) (Tyrosine-protein kinase Kit),Mast/stem cell growth factor receptor kita (SCFR) (EC 2.7.10.1) (Tyrosine-protein kinase Kit),GO:0005524; GO:0038093; GO:0038109; GO:0030154; GO:0016021; GO:0046872; GO:0018108; GO:0005886; GO:0004716; GO:0023014; GO:0004714,ATP binding; Fc receptor signaling pathway; Kit signaling pathway; cell differentiation; integral to membrane; metal ion binding; peptidyl-tyrosine phosphorylation; plasma membrane; receptor signaling protein tyrosine kinase activity; signal transduction by phosphorylation; transmembrane receptor protein tyrosine kinase activity,PF07714;,,,,,,,,,KITA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),developmental pigmentation [GO:0048066]; Fc receptor signaling pathway [GO:0038093]; gastro-intestinal system smooth muscle contraction [GO:0014831]; Kit signaling pathway [GO:0038109]; melanocyte apoptotic process [GO:1902362]; melanocyte differentiation [GO:0030318]; melanocyte migration [GO:0097324]; stem cell fate commitment [GO:0048865] comp114532_c0_seq1,513,43.4698,0.2901156,15,82,,,,,,,,,4.00E-43,CHOYP_LOC100372110.1.1,,,,,,,,, comp114532_c2_seq1,476,42.437,0.61979284,5,68,,2.00E-69,O00400,Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1),Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1),GO:0000139; GO:0008521; GO:0008219; GO:0005789; GO:0005887; GO:0055085,Golgi membrane; acetyl-CoA transporter activity; cell death; endoplasmic reticulum membrane; integral to plasma membrane; transmembrane transport,PF13000;,,,,,,,,,ACATN_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; SMAD protein signal transduction [GO:0060395]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp114543_c2_seq1,655,44.2748,0.65634533,14,126,,9.00E-20,Q52KB5,Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450),Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp114545_c0_seq1,295,43.3898,0.4423463,7,8,,6.00E-49,Q9Z2D1,Myotubularin-related protein 2 (EC 3.1.3.-),"Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)",GO:0031901; GO:0046855; GO:0032288; GO:0031642; GO:0048666; GO:0005634; GO:0035335; GO:0046856; GO:0052866; GO:0051262; GO:0004725; GO:0005774,early endosome membrane; inositol phosphate dephosphorylation; myelin assembly; negative regulation of myelination; neuron development; nucleus; peptidyl-tyrosine dephosphorylation; phosphatidylinositol dephosphorylation; phosphatidylinositol phosphate phosphatase activity; protein tetramerization; protein tyrosine phosphatase activity; vacuolar membrane,PF02893;PF06602;,6.00E-51,CHOYP_LOC100313661.1.1,,,,,,,MTMR2_MOUSE,Mus musculus (Mouse),dendritic spine maintenance [GO:0097062]; dephosphorylation [GO:0016311]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein tetramerization [GO:0051262] comp114545_c1_seq1,515,45.8252,0.52853579,17,31,,1.00E-72,Q5ZIV1,Myotubularin-related protein 2 (EC 3.1.3.-),"Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)",GO:0005737; GO:0016020; GO:0035335; GO:0004725,cytoplasm; membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF02893;PF06602;,,,,,,,,,MTMR2_CHICK,Gallus gallus (Chicken),phosphatidylinositol dephosphorylation [GO:0046856] comp114545_c3_seq1,409,44.2543,0.15222863,17,28,,5.00E-33,Q6TEL0,Myotubularin-related protein 8 (Myotubularin-related protein 6),Myotubularin-related protein 8 (Myotubularin-related protein 6),GO:0005635; GO:0035335; GO:0004725,nuclear envelope; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF06602;,,,,,,,,,MTMR8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),blood vessel development [GO:0001568]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of autophagy [GO:0010506] comp114552_c2_seq1,456,35.5263,0.21539774,16,26,,,,,,,,,,,4.00E-15,ruditapes_c30936,,,,,,, comp114554_c1_seq1,609,36.289,1.14232518,7,90,,3.00E-09,Q8N9K5,Zinc finger protein 565,Zinc finger protein 565,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN565_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp114565_c0_seq1,909,44.8845,0.52003939,11,100,,2.00E-62,A8E657,"Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]","Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]",GO:0033512; GO:0005739; GO:0047131; GO:0047130,"L-lysine catabolic process to acetyl-CoA via saccharopine; mitochondrion; saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity; saccharopine dehydrogenase (NADP+, L-lysine-forming) activity",PF05222;PF16653;PF03435;,5.00E-26,CHOYP_LOC100906268.2.2,2.00E-23,ruditapes_c13976,,,,,AASS_BOVIN,Bos taurus (Bovine),L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512] comp114565_c1_seq1,314,47.4522,0.46154314,7,6,,,,,,,,,3.00E-49,CHOYP_LOC100123521.2.2,,,,,,,,, comp114568_c0_seq1,1042,41.8426,0.81539544,22,100,,2.00E-38,Q96HA9,Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma),Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma),GO:0005779; GO:0031231; GO:0016559; GO:0043234; GO:0044375,integral to peroxisomal membrane; intrinsic to peroxisomal membrane; peroxisome fission; protein complex; regulation of peroxisome size,PF05648;,,,,,,,,,PX11C_HUMAN,Homo sapiens (Human),peroxisome fission [GO:0016559]; regulation of peroxisome size [GO:0044375] comp114571_c1_seq1,475,40.2105,1.00377803,14,26,,4.00E-27,Q04652,Ring canal kelch protein [Cleaved into: Kelch short protein],Ring canal kelch protein [Cleaved into: Kelch short protein],GO:0003779; GO:0030036; GO:0007349; GO:0005737; GO:0005856; GO:0007301; GO:0035183; GO:0030717; GO:0007297; GO:0030723,actin binding; actin cytoskeleton organization; cellularization; cytoplasm; cytoskeleton; female germline ring canal formation; female germline ring canal inner rim; karyosome formation; ovarian follicle cell migration; ovarian fusome organization,PF07707;PF00651;PF01344;,,,,,,,,,KELC_DROME,Drosophila melanogaster (Fruit fly),"actin cytoskeleton organization [GO:0030036]; cellularization [GO:0007349]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; female germline ring canal formation [GO:0007301]; karyosome formation [GO:0030717]; oogenesis [GO:0048477]; ovarian follicle cell migration [GO:0007297]; ovarian fusome organization [GO:0030723]; ovarian nurse cell to oocyte transport [GO:0007300]; protein ubiquitination [GO:0016567]" comp114571_c2_seq1,1284,36.6044,0.86494258,122,85,,9.00E-30,Q9ER30,Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin),Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin),GO:0031463; GO:0031430; GO:0006928; GO:0005813; GO:0005856; GO:0030239; GO:0005730; GO:0005886; GO:0016567; GO:0031143; GO:0031275; GO:0045661; GO:2000291; GO:2001014; GO:0001726; GO:0035914,Cul3-RING ubiquitin ligase complex; M band; cellular component movement; centrosome; cytoskeleton; myofibril assembly; nucleolus; plasma membrane; protein ubiquitination; pseudopodium; regulation of lateral pseudopodium assembly; regulation of myoblast differentiation; regulation of myoblast proliferation; regulation of skeletal muscle cell differentiation; ruffle; skeletal muscle cell differentiation,PF07707;PF00651;PF01344;,1.00E-17,CHOYP_KLH41.1.1,,,,,,,KBTBA_RAT,Rattus norvegicus (Rat),myofibril assembly [GO:0030239]; protein ubiquitination [GO:0016567]; regulation of lateral pseudopodium assembly [GO:0031275]; regulation of myoblast differentiation [GO:0045661]; regulation of myoblast proliferation [GO:2000291]; regulation of skeletal muscle cell differentiation [GO:2001014]; sarcomere organization [GO:0045214]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle fiber development [GO:0048741] comp114576_c0_seq1,541,48.7985,0.32684186,33,11,,6.00E-42,Q5G271,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0031410; GO:0030425; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252; GO:0043083; GO:0043195; GO:0031638,axon; cytoplasmic vesicle; dendrite; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity; synaptic cleft; terminal bouton; zymogen activation,PF00051;PF00530;PF00089;,1.00E-17,CHOYP_LOC100636340.1.4,,,,,,,NETR_PANTR,Pan troglodytes (Chimpanzee),exocytosis [GO:0006887]; zymogen activation [GO:0031638] comp114584_c0_seq1,420,41.1905,0.66825776,13,39,,3.00E-28,Q9JM93,ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4),ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4) (Splicing factor SRrp37),,,PF10500;,8.00E-13,CHOYP_AR6P4.1.1,,,,,,,AR6P4_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp114617_c0_seq1,327,37.9205,0.26430545,11,14,,4.00E-11,Q9Z0R4,Intersectin-1 (EH and SH3 domains protein 1),Intersectin-1 (EH and SH3 domains protein 1),GO:0005089; GO:0005509; GO:0030054; GO:0005905; GO:0030139; GO:0006897; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0005543; GO:0005886; GO:0051897; GO:0035023; GO:0007264; GO:0045202,Rho guanyl-nucleotide exchange factor activity; calcium ion binding; cell junction; coated pit; endocytic vesicle; endocytosis; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; phospholipid binding; plasma membrane; positive regulation of protein kinase B signaling cascade; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; synapse,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,,,,,,,,,ITSN1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp114617_c1_seq1,444,40.5405,0.72312867,13,22,,,,,,,,,9.00E-32,CHOYP_BRAFLDRAFT_79602.1.1,,,,,,,,, comp114617_c2_seq1,681,41.2628,0.49760374,25,53,,1.00E-16,Q8IVI9,Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer),Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer),GO:0003677; GO:0005856; GO:0030666; GO:0006897; GO:0045892; GO:0046209; GO:0005634; GO:0005886; GO:0050999; GO:0007165; GO:0044281,"DNA binding; cytoskeleton; endocytic vesicle membrane; endocytosis; negative regulation of transcription, DNA-dependent; nitric oxide metabolic process; nucleus; plasma membrane; regulation of nitric-oxide synthase activity; signal transduction; small molecule metabolic process",PF00611;PF14604;,6.00E-30,CHOYP_PHUM_PHUM498480.1.1,,,,,,,NOSTN_HUMAN,Homo sapiens (Human),"endocytosis [GO:0006897]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of nitric-oxide synthase activity [GO:0050999]; signal transduction [GO:0007165]" comp114620_c0_seq1,215,61.3953,1.1969781,2,4,,9.00E-42,Q6A6Y0,Succinyl-CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta),Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta),GO:0005524; GO:0000287; GO:0030145; GO:0004775; GO:0006099,ATP binding; magnesium ion binding; manganese ion binding; succinate-CoA ligase (ADP-forming) activity; tricarboxylic acid cycle,PF08442;PF00549;,,,,,,,,,SUCC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),tricarboxylic acid cycle [GO:0006099] comp114623_c1_seq1,573,36.6492,0.31980783,29,20,,7.00E-17,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp114628_c0_seq1,816,45.098,0.62730438,47,53,,6.00E-73,Q96T49,Protein phosphatase 1 regulatory inhibitor subunit 16B (Ankyrin repeat domain-containing protein 4) (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein) (hTIMAP),Protein phosphatase 1 regulatory inhibitor subunit 16B (Ankyrin repeat domain-containing protein 4) (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein) (hTIMAP),GO:0005634; GO:0005886; GO:0019903; GO:0051489; GO:0007165,nucleus; plasma membrane; protein phosphatase binding; regulation of filopodium assembly; signal transduction,PF12796;,4.00E-77,CHOYP_LOC581083.1.1,,,,,,,PP16B_HUMAN,Homo sapiens (Human),establishment of endothelial barrier [GO:0061028]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of filopodium assembly [GO:0051489]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp114632_c0_seq1,724,41.0221,0.74352184,6,69,,3.00E-18,P56962,Syntaxin-17,Syntaxin-17,GO:0030134; GO:0012507; GO:0006888; GO:0007030; GO:0005484; GO:0000149; GO:0031201; GO:0000046; GO:0000421; GO:0005829; GO:0005793; GO:0033116; GO:0097111; GO:0006887; GO:0016021; GO:0006886; GO:0005739; GO:0030868,ER to Golgi transport vesicle; ER to Golgi transport vesicle membrane; ER to Golgi vesicle-mediated transport; Golgi organization; SNAP receptor activity; SNARE binding; SNARE complex; autophagic vacuole fusion; autophagic vacuole membrane; cytosol; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; endoplasmic reticulum-Golgi intermediate compartment organization; exocytosis; integral to membrane; intracellular protein transport; mitochondrion; smooth endoplasmic reticulum membrane,,4.00E-32,CHOYP_STX17.1.1,,,,,,,STX17_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein localization to pre-autophagosomal structure [GO:0034497]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] comp114635_c0_seq1,763,41.1533,0.42276495,0,11,,7.00E-92,Q68EK7,Ras-related protein Rab-4B,Ras-related protein Rab-4B,GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAB4B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264] comp114635_c0_seq2,509,44.0079,0.38059848,11,0,,2.00E-52,Q05975,Ras-related protein Rab-2,Ras-related protein Rab-2,GO:0005525; GO:0000139; GO:0005789; GO:0033116; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00071;,1.00E-106,CHOYP_RAB4B.1.1,8.00E-12,ruditapes_c14666,,,,,RAB2_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp114638_c0_seq1,222,37.3874,0.39539809,6,8,,1.00E-10,Q5RD78,Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2),Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2),GO:0004842,ubiquitin-protein ligase activity,PF00632;,,,,,,,,,HECD2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp114645_c0_seq1,254,36.2205,0.48296203,6,71,,2.00E-06,A2VDW9,Zinc finger protein Aiolos (Ikaros family zinc finger protein 3),Zinc finger protein Aiolos (Ikaros family zinc finger protein 3),GO:0042113; GO:0005737; GO:0046872; GO:0005634; GO:0046982; GO:0042803; GO:0045577; GO:0030888; GO:0042981; GO:0006355; GO:0043565; GO:0006351,"B cell activation; cytoplasm; metal ion binding; nucleus; protein heterodimerization activity; protein homodimerization activity; regulation of B cell differentiation; regulation of B cell proliferation; regulation of apoptotic process; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF00096;,,,,,,,,,IKZF3_BOVIN,Bos taurus (Bovine),"B cell activation [GO:0042113]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of B cell proliferation [GO:0030888]; regulation of lymphocyte differentiation [GO:0045619]; transcription, DNA-templated [GO:0006351]" comp114648_c1_seq2,762,46.7192,0.65938084,8,84,,9.00E-15,Q9NX45,Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2,Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2,GO:0003677; GO:0030154; GO:0007275; GO:0005634; GO:0048477; GO:0006355; GO:0007283; GO:0006351,"DNA binding; cell differentiation; multicellular organismal development; nucleus; oogenesis; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF00010;,1.00E-19,CHOYP_LOC100667675.1.1,,,,,,,SOLH2_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366] comp114652_c0_seq1,1305,42.3755,0.34166142,31,138,,9.00E-28,Q60674,Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),GO:0003677; GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0004887; GO:0008270,DNA binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,4.00E-42,CHOYP_E75.2.3,,,,,,,NR1D2_MOUSE,Mus musculus (Mouse),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp114654_c0_seq1,598,44.9833,1.06738243,18,116,,4.00E-09,O88992,C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1),C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1),GO:0005581; GO:0005737,collagen; cytoplasm,PF00386;PF01391;,,,,,,,,,C1QRF_MOUSE,Mus musculus (Mouse),maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322] comp114655_c0_seq1,298,42.6174,0.37356743,5,1,,6.00E-12,Q5RA67,Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1),Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1),GO:0005524; GO:0004674; GO:0005840,ATP binding; protein serine/threonine kinase activity; ribosome,PF04212;PF00069;,5.00E-26,CHOYP_LOC100371127.1.1,,,,,,,RPKL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp114655_c2_seq1,591,39.2555,0.22540424,24,13,,1.00E-24,Q96S38,Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein),Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein),GO:0005524; GO:0005769; GO:0016020; GO:0035091; GO:0004674; GO:0007165,ATP binding; early endosome; membrane; phosphatidylinositol binding; protein serine/threonine kinase activity; signal transduction,PF04212;PF00069;PF00787;,,,,,,,,,KS6C1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp114667_c0_seq2,626,42.492,0.61798627,10,21,,4.00E-80,Q6EV77,"Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)","Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)",GO:0032580; GO:0036071; GO:0016477; GO:0008424; GO:0016021; GO:0007229; GO:0033578; GO:0043112; GO:0007585; GO:0007179,Golgi cisterna membrane; N-glycan fucosylation; cell migration; glycoprotein 6-alpha-L-fucosyltransferase activity; integral to membrane; integrin-mediated signaling pathway; protein glycosylation in Golgi; receptor metabolic process; respiratory gaseous exchange; transforming growth factor beta receptor signaling pathway,PF14604;,5.00E-43,CHOYP_FUT8.1.1,,,,,,,FUT8_PANTR,Pan troglodytes (Chimpanzee),cell migration [GO:0016477]; GDP-L-fucose metabolic process [GO:0046368]; integrin-mediated signaling pathway [GO:0007229]; N-glycan fucosylation [GO:0036071]; N-glycan processing [GO:0006491]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor metabolic process [GO:0043112]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; respiratory gaseous exchange [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp114670_c1_seq1,816,44.9755,0.31740529,21,86,,3.00E-70,Q2PFD7,PH and SEC7 domain-containing protein 3 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Pleckstrin homology and SEC7 domain-containing protein 3),PH and SEC7 domain-containing protein 3 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Pleckstrin homology and SEC7 domain-containing protein 3),GO:0005086; GO:0032011; GO:0030054; GO:0016020; GO:0030182; GO:0005543; GO:0014069; GO:0045211; GO:0032012,ARF guanyl-nucleotide exchange factor activity; ARF protein signal transduction; cell junction; membrane; neuron differentiation; phospholipid binding; postsynaptic density; postsynaptic membrane; regulation of ARF protein signal transduction,PF01369;,,,,,,,,,PSD3_MOUSE,Mus musculus (Mouse),ARF protein signal transduction [GO:0032011]; regulation of ARF protein signal transduction [GO:0032012] comp114670_c2_seq1,445,41.573,0.52164006,18,18,,5.00E-10,P97694,"Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog A) (rSec7-1)","Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog A) (rSec7-1)",GO:0005086; GO:0005737; GO:0005543; GO:0005886; GO:0032012; GO:0030155,ARF guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; plasma membrane; regulation of ARF protein signal transduction; regulation of cell adhesion,PF00169;PF01369;,3.00E-38,CHOYP_LOC100864134.1.1,,,,,,,CYH1_RAT,Rattus norvegicus (Rat),regulation of ARF protein signal transduction [GO:0032012] comp114683_c0_seq1,792,42.6768,0.63986898,25,57,,2.00E-78,Q91YX5,Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (EC 2.3.1.-),Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (EC 2.3.1.-),GO:0005789; GO:0016021; GO:0008654; GO:0016746,"endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process; transferase activity, transferring acyl groups",PF16076;PF01553;,4.00E-20,CHOYP_LOC100494107.1.1,,,,,,,LGAT1_MOUSE,Mus musculus (Mouse),phospholipid biosynthetic process [GO:0008654] comp114695_c0_seq1,739,43.4371,1.00825473,46,164,,4.00E-65,Q9GUM2,"Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)","Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)",GO:0033207; GO:0075015; GO:0016021; GO:0046872; GO:0045747; GO:0006486; GO:0009636,"beta-1,4-N-acetylgalactosaminyltransferase activity; formation of infection structure on or near host; integral to membrane; metal ion binding; positive regulation of Notch signaling pathway; protein glycosylation; response to toxic substance",PF02709;PF13733;,,,,,,,,,BRE4_CAEEL,Caenorhabditis elegans,formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636] comp114697_c0_seq1,718,42.0613,0.59916783,30,137,,6.00E-89,Q5U3U3,"Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)","Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)",GO:0004095; GO:0006635; GO:0005743; GO:0006810,carnitine O-palmitoyltransferase activity; fatty acid beta-oxidation; mitochondrial inner membrane; transport,PF00755;,3.00E-15,CHOYP_CPT2.1.1,,,,,,,CPT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810] comp114704_c0_seq1,445,33.4831,0.77074122,8,141,,,,,,,,,7.00E-14,CHOYP_contig_041133,,,,,,,,, comp114713_c0_seq1,873,35.7388,0.29314142,13,88,,8.00E-52,P42577,Soma ferritin (EC 1.16.3.1),Soma ferritin (EC 1.16.3.1),GO:0006879; GO:0005737; GO:0008199; GO:0004322; GO:0006826,cellular iron ion homeostasis; cytoplasm; ferric iron binding; ferroxidase activity; iron ion transport,PF00210;,1.00E-39,CHOYP_FRIS.10.11,3.00E-13,ruditapes_lrc6827,,,,,FRIS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] comp11472_c0_seq1,243,44.0329,1.2243935,2,0,,,,,,,,,5.00E-13,CHOYP_TRI55.2.2,,,,,,,,, comp114731_c0_seq1,673,38.1872,0.98000943,4,133,,,,,,,,,,,2.00E-15,ruditapes_c27760,,,,,,, comp114733_c0_seq1,664,47.8916,0.31888184,1,0,,7.00E-43,Q8BR93,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_MOUSE,Mus musculus (Mouse), comp114734_c0_seq1,843,45.5516,0.53425147,15,14,,2.00E-45,Q9BE74,Low-density lipoprotein receptor-related protein 12 (LRP-12) (Fragment),Low-density lipoprotein receptor-related protein 12 (LRP-12) (Fragment),GO:0005905; GO:0006897; GO:0016021,coated pit; endocytosis; integral to membrane,PF00431;PF00057;,,,,,,,,,LRP12_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),endocytosis [GO:0006897] comp114740_c1_seq1,806,42.1836,0.48794356,34,28,,1.00E-94,Q8VHI3,GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2),GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2),GO:0005794; GO:0005783; GO:0006004; GO:0001707; GO:0046922; GO:0010717; GO:0010468; GO:0051046,Golgi apparatus; endoplasmic reticulum; fucose metabolic process; mesoderm formation; peptide-O-fucosyltransferase activity; regulation of epithelial to mesenchymal transition; regulation of gene expression; regulation of secretion,PF10250;,4.00E-45,CHOYP_LOC100368416.1.1,,,,,,,OFUT2_MOUSE,Mus musculus (Mouse),fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; mesoderm formation [GO:0001707]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046] comp114759_c0_seq2,958,44.4676,0.48859259,59,0,,8.00E-43,Q55E58,Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),GO:0005524; GO:0005525; GO:0042641; GO:0000281; GO:0004721; GO:0006470; GO:0004674; GO:0007264,ATP binding; GTP binding; actomyosin; mitotic cytokinesis; phosphoprotein phosphatase activity; protein dephosphorylation; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF16095;PF06602;PF07714;PF08477;,4.00E-53,CHOYP_TRIADDRAFT_57945.1.3,,,,,,,PATS1_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176] comp114759_c0_seq4,626,46.4856,0.38604816,7,0,,7.00E-24,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,4.00E-31,CHOYP_TRIADDRAFT_57945.3.3,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp114779_c1_seq1,412,45.3883,0.4895714,9,21,,8.00E-64,Q7ZTW4,Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1),Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1),GO:0005524; GO:0006915; GO:0005783; GO:0005634; GO:0004674; GO:0006950,ATP binding; apoptotic process; endoplasmic reticulum; nucleus; protein serine/threonine kinase activity; response to stress,PF00069;PF00433;,5.00E-79,CHOYP_LOC100367908.2.2,,,,,,,SGK1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; cellular sodium ion homeostasis [GO:0006883]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; neuron projection morphogenesis [GO:0048812]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transporter activity [GO:0032411]; regulation of apoptotic process [GO:0042981]; regulation of cell growth [GO:0001558]; regulation of cell proliferation [GO:0042127] comp114780_c0_seq1,959,39.2075,0.35454584,46,129,,5.00E-41,Q96J42,Thioredoxin domain-containing protein 15,Thioredoxin domain-containing protein 15,GO:0045454; GO:0016021,cell redox homeostasis; integral to membrane,PF00085;,4.00E-21,CHOYP_LOC100877516.1.1,,,,,,,TXD15_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454] comp114784_c0_seq1,757,38.3091,0.39978973,36,65,,5.00E-76,Q5RD78,Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2),Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2),GO:0004842,ubiquitin-protein ligase activity,PF00632;,2.00E-62,CHOYP_HECTD2.1.1,,,,,,,HECD2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp114801_c0_seq1,511,44.227,0.76209669,1,83,,8.00E-06,Q9CAT6,Organic cation/carnitine transporter 1 (AtOCT1),Organic cation/carnitine transporter 1 (AtOCT1),GO:0005524; GO:0015226; GO:0016021; GO:0010150; GO:0005886,ATP binding; carnitine transmembrane transporter activity; integral to membrane; leaf senescence; plasma membrane,PF00083;,,,,,,,,,OCT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cadaverine transport [GO:0015839]; leaf senescence [GO:0010150] comp114801_c1_seq1,512,44.7266,0.6105228,4,53,,2.00E-06,Q3UHH2,Solute carrier family 22 member 23,Solute carrier family 22 member 23,GO:0016021; GO:0006811; GO:0022857,integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,S22AN_MOUSE,Mus musculus (Mouse), comp114801_c1_seq2,478,41.6318,0.88069844,0,14,,2.00E-18,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp114801_c1_seq3,570,39.6491,0.9497851,6,27,,9.00E-08,Q17NV8,Facilitated trehalose transporter Tret1,Facilitated trehalose transporter Tret1,GO:0016021; GO:0005886; GO:0015574,integral to membrane; plasma membrane; trehalose transmembrane transporter activity,PF00083;,,,,,,,,,TRET1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),trehalose transport [GO:0015771] comp114807_c0_seq1,657,45.5099,0.4150681,0,2,,8.00E-10,O59679,Rho guanine nucleotide exchange factor gef3,Rho guanine nucleotide exchange factor gef3,GO:0005096; GO:0005089; GO:0000917; GO:0032153; GO:0005829; GO:0043547; GO:0032319,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; barrier septum assembly; cell division site; cytosol; positive regulation of GTPase activity; regulation of Rho GTPase activity,PF00621;,,,,,,,,,GEF3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),barrier septum assembly [GO:0000917]; positive regulation of cell separation after cytokinesis [GO:2001043]; regulation of GTPase activity [GO:0043087]; regulation of protein localization to cell division site [GO:1901900]; regulation of Rho protein signal transduction [GO:0035023] comp114807_c0_seq3,846,43.7352,0.42569165,3,7,,1.00E-37,Q6TXD4,Dynamin-binding protein (Scaffold protein Tuba),Dynamin-binding protein (Scaffold protein Tuba),GO:0005795; GO:0005089; GO:0030054; GO:0005856; GO:0035556; GO:0035023; GO:0045202,Golgi stack; Rho guanyl-nucleotide exchange factor activity; cell junction; cytoskeleton; intracellular signal transduction; regulation of Rho protein signal transduction; synapse,PF03114;PF00621;PF00018;PF07653;PF14604;,2.00E-68,CHOYP_BRAFLDRAFT_91062.1.1,,,,,,,DNMBP_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023] comp114809_c0_seq1,432,43.5185,0.24979942,32,30,,5.00E-08,Q96RL7,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),GO:0006895; GO:0008219; GO:0031045; GO:0005622; GO:0007626; GO:0007399; GO:0008104; GO:0015031; GO:0035176,Golgi to endosome transport; cell death; dense core granule; intracellular; locomotory behavior; nervous system development; protein localization; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp114823_c0_seq1,932,35.6223,0.38108543,28,16,,2.00E-18,B0BLT4,Glycolipid transfer protein (GLTP),Glycolipid transfer protein (GLTP),GO:0005737; GO:0051861; GO:0046836; GO:0017089,cytoplasm; glycolipid binding; glycolipid transport; glycolipid transporter activity,PF08718;,,,,,,,,,GLTP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp114823_c0_seq2,545,35.5963,0.29632141,0,0,,8.00E-11,B0YN54,Glycolipid transfer protein (GLTP),Glycolipid transfer protein (GLTP),GO:0005737; GO:0051861; GO:0046836; GO:0017089,cytoplasm; glycolipid binding; glycolipid transport; glycolipid transporter activity,PF08718;,,,,,,,,,GLTP_PANTR,Pan troglodytes (Chimpanzee), comp114827_c0_seq1,1027,42.5511,0.39336772,49,73,,7.00E-13,Q9BXT4,Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1),Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1),GO:0043046; GO:0033391; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; chromatoid body; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_HUMAN,Homo sapiens (Human),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp114828_c0_seq1,681,43.1718,0.34757303,25,51,,6.00E-27,Q12789,General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),GO:0042791; GO:0003677; GO:0005730; GO:0005654; GO:0030529; GO:0042797; GO:0000127,5S class rRNA transcription from RNA polymerase III type 1 promoter; DNA binding; nucleolus; nucleoplasm; ribonucleoprotein complex; tRNA transcription from RNA polymerase III promoter; transcription factor TFIIIC complex,PF04182;,,,,,,,,,TF3C1_HUMAN,Homo sapiens (Human),"5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; rRNA transcription [GO:0009303]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription [GO:0009304]; tRNA transcription from RNA polymerase III promoter [GO:0042797]" comp114837_c0_seq1,440,38.4091,1.07747035,5,123,,5.00E-18,Q8IYS1,Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),GO:0016787,hydrolase activity,PF07687;PF01546;,,,1.00E-20,ruditapes_c26452,,,,,P20D2_HUMAN,Homo sapiens (Human),proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268] comp114839_c0_seq1,1230,39.8374,0.5578179,60,120,,6.00E-161,P0CG08,Golgi pH regulator B (Protein GPR89B),Golgi pH regulator B (Protein GPR89B),GO:0000139; GO:0016021; GO:0015031; GO:0005244,Golgi membrane; integral to membrane; protein transport; voltage-gated ion channel activity,PF12430;PF12537;,1.00E-173,CHOYP_GPHRB.1.1,,,,,,,GPHRB_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp114843_c0_seq1,249,44.1767,1.30165237,0,38,,1.00E-27,P10079,Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),GO:0032579; GO:0005509; GO:0016023; GO:0005615,apical lamina of hyaline layer; calcium ion binding; cytoplasmic membrane-bounded vesicle; extracellular space,PF01382;PF00431;PF00008;,,,,,,,,,FBP1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp114844_c0_seq1,519,31.9846,0.31515269,16,89,,1.00E-06,O75362,Zinc finger protein 217,Zinc finger protein 217,GO:0000118; GO:0046872; GO:0045892; GO:0003700; GO:0044212; GO:0006351,"histone deacetylase complex; metal ion binding; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",,,,,,,,,,ZN217_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp114845_c0_seq1,339,43.9528,0.49062476,6,15,,2.00E-34,Q6A009,E3 ubiquitin-protein ligase listerin (EC 6.3.2.-) (RING finger protein 160) (Zinc finger protein 294) (Zfp-294),E3 ubiquitin-protein ligase listerin (EC 6.3.2.-) (RING finger protein 160) (Zinc finger protein 294) (Zfp-294),GO:0008219; GO:0051865; GO:0004842; GO:0008270,cell death; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,LTN1_MOUSE,Mus musculus (Mouse),protein autoubiquitination [GO:0051865] comp114846_c0_seq2,1062,46.2335,0.59986775,25,8,,2.00E-174,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,4.00E-173,CHOYP_DNAH5.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp114856_c0_seq2,1281,40.203,0.23221146,26,56,,1.00E-42,Q5TYW4,Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),GO:0009790; GO:0000184,"embryo development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",PF15492;PF08314;,,,,,,,,,NBAS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp114857_c0_seq1,296,39.8649,0.78227407,13,60,,3.00E-11,Q6NXR0,Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1),Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1),GO:0005525; GO:0016817; GO:0016020,"GTP binding; hydrolase activity, acting on acid anhydrides; membrane",PF05049;,,,,,,,,,IIGP5_HUMAN,Homo sapiens (Human), comp114882_c0_seq2,278,35.9712,0.69203045,1,15,,4.00E-08,O42842,Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7),Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7),GO:0044209; GO:0003999; GO:0006168; GO:0005829; GO:0046872; GO:0005634; GO:0006166,AMP salvage; adenine phosphoribosyltransferase activity; adenine salvage; cytosol; metal ion binding; nucleus; purine ribonucleoside salvage,PF00156;,,,,,,,,,APT_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),adenine salvage [GO:0006168]; AMP biosynthetic process [GO:0006167]; AMP salvage [GO:0044209] comp114888_c0_seq1,664,47.1386,0.51740494,34,18,,4.00E-68,P42859,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0006888; GO:0051938; GO:0009952; GO:0030424; GO:0008088; GO:0007569; GO:0000052; GO:0016023; GO:0008340; GO:0050809; GO:0007212; GO:0007029; GO:0016197; GO:0007625; GO:0042445; GO:0016234; GO:0030073; GO:0055072; GO:0019244; GO:0007626; GO:0043524; GO:0021990; GO:0051402; GO:0048666; GO:0005634; GO:0021988; GO:0048341; GO:0006606; GO:0019805; GO:0046902; GO:0051881; GO:0048167; GO:0051592; GO:0035176; GO:0007283; GO:0021756; GO:0000050; GO:0047496; GO:0008542,ER to Golgi vesicle-mediated transport; L-glutamate import; anterior/posterior pattern specification; axon; axon cargo transport; cell aging; citrulline metabolic process; cytoplasmic membrane-bounded vesicle; determination of adult lifespan; diazepam binding; dopamine receptor signaling pathway; endoplasmic reticulum organization; endosomal transport; grooming behavior; hormone metabolic process; inclusion body; insulin secretion; iron ion homeostasis; lactate biosynthetic process from pyruvate; locomotory behavior; negative regulation of neuron apoptotic process; neural plate formation; neuron apoptotic process; neuron development; nucleus; olfactory lobe development; paraxial mesoderm formation; protein import into nucleus; quinolinate biosynthetic process; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; regulation of synaptic plasticity; response to calcium ion; social behavior; spermatogenesis; striatum development; urea cycle; vesicle transport along microtubule; visual learning,PF12372;,3.00E-59,CHOYP_HD.1.1,,,,,,,HD_MOUSE,Mus musculus (Mouse),"anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; associative learning [GO:0008306]; axo-dendritic transport [GO:0008088]; brain development [GO:0007420]; cell aging [GO:0007569]; central nervous system development [GO:0007417]; citrulline metabolic process [GO:0000052]; determination of adult lifespan [GO:0008340]; dopamine receptor signaling pathway [GO:0007212]; endoplasmic reticulum organization [GO:0007029]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insulin secretion [GO:0030073]; iron ion homeostasis [GO:0055072]; lactate biosynthetic process from pyruvate [GO:0019244]; learning [GO:0007612]; learning or memory [GO:0007611]; L-glutamate import [GO:0051938]; locomotory behavior [GO:0007626]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; neural plate formation [GO:0021990]; neurogenesis [GO:0022008]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; olfactory lobe development [GO:0021988]; paraxial mesoderm formation [GO:0048341]; peptide hormone secretion [GO:0030072]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein import into nucleus [GO:0006606]; protein localization to centrosome [GO:0071539]; quinolinate biosynthetic process [GO:0019805]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein phosphatase type 2A activity [GO:0034047]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; social behavior [GO:0035176]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; urea cycle [GO:0000050]; vesicle transport along microtubule [GO:0047496]; visual learning [GO:0008542]; vocal learning [GO:0042297]" comp114890_c0_seq1,762,41.0761,0.12497974,32,186,,,,,,,,,6.00E-94,CHOYP_CEP76.1.1,,,,,,,,, comp114890_c1_seq1,1102,43.1034,0.39809467,38,140,,1.00E-152,Q6DDX8,Centrosomal protein of 76 kDa (Cep76),Centrosomal protein of 76 kDa (Cep76),GO:0005814; GO:0046599,centriole; regulation of centriole replication,PF15627;,,,,,,,,,CEP76_XENLA,Xenopus laevis (African clawed frog),regulation of centriole replication [GO:0046599] comp114904_c0_seq1,528,40.7197,0.80194688,100,238,,,,,,,,,,,2.00E-26,ruditapes2_c2224,,,,,,, comp114907_c0_seq1,203,48.7685,0.87181603,7,95,,,,,,,,,5.00E-31,CHOYP_LOC100353582.2.2,,,,,,,,, comp114919_c0_seq1,344,29.6512,0.53241191,20,52,,,,,,,,,5.00E-14,CHOYP_contig_030752,2.00E-11,ruditapes_c18116,,,,,,, comp114921_c0_seq1,965,41.658,0.95928604,22,169,,5.00E-28,P98157,Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),GO:0005509; GO:0005905; GO:0006897; GO:0016021,calcium ion binding; coated pit; endocytosis; integral to membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp114936_c0_seq1,328,48.7805,0.52222708,9,17,,3.00E-43,P50430,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0007417; GO:0005764; GO:0046872; GO:0005739; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; central nervous system development; lysosome; metal ion binding; mitochondrion; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,8.00E-37,CHOYP_LOC100377677.1.2,,,,,,,ARSB_RAT,Rattus norvegicus (Rat),autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] comp114943_c0_seq1,678,49.705,0.48413653,16,38,,2.00E-73,Q9V9A7,"Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)","Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)",GO:0005524; GO:0009062; GO:0006550; GO:0006552; GO:0009087; GO:0004485; GO:0005759; GO:0004658; GO:0007563; GO:0006567; GO:0006574,ATP binding; fatty acid catabolic process; isoleucine catabolic process; leucine catabolic process; methionine catabolic process; methylcrotonoyl-CoA carboxylase activity; mitochondrial matrix; propionyl-CoA carboxylase activity; regulation of eclosion; threonine catabolic process; valine catabolic process,PF01039;,5.00E-69,CHOYP_LOC100222774.1.1,,,,,,,MCCB_DROME,Drosophila melanogaster (Fruit fly),leucine catabolic process [GO:0006552]; leucine metabolic process [GO:0006551]; regulation of eclosion [GO:0007563] comp114944_c1_seq1,235,42.9787,1.01805765,8,33,,1.00E-17,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,3.00E-15,CHOYP_NEMVEDRAFT_V1G199235.3.15,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp114969_c1_seq1,878,48.2916,0.36024637,17,56,,3.00E-61,A0LNW5,Hydroxylamine reductase (EC 1.7.-.-) (Hybrid-cluster protein) (HCP),Hydroxylamine reductase (EC 1.7.99.1) (Hybrid-cluster protein) (HCP) (Prismane protein),GO:0051539; GO:0005737; GO:0050418; GO:0046872,"4 iron, 4 sulfur cluster binding; cytoplasm; hydroxylamine reductase activity; metal ion binding",PF03063;,,,,,,,,,HCP_SYNFM,Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB), comp114969_c2_seq1,590,44.9153,0.47134692,10,66,,1.00E-29,O27502,Hydroxylamine reductase (EC 1.7.-.-) (Hybrid-cluster protein) (HCP),Hydroxylamine reductase (EC 1.7.99.1) (Hybrid-cluster protein) (HCP) (Prismane protein),GO:0051539; GO:0005737; GO:0050418; GO:0046872,"4 iron, 4 sulfur cluster binding; cytoplasm; hydroxylamine reductase activity; metal ion binding",PF03063;,,,4.00E-16,ruditapes_c28049,,,,,HCP_METTH,Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum), comp114975_c0_seq1,518,39.9614,0.20341052,0,0,,4.00E-06,Q8HZ58,Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein),Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein),GO:0030154; GO:0005814; GO:0007275; GO:0005634,cell differentiation; centriole; multicellular organismal development; nucleus,PF07111;,,,,,,,,,CCHCR_PONPY,Pongo pygmaeus (Bornean orangutan),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp114975_c0_seq2,689,39.9129,0.30507415,16,18,,9.00E-21,Q8HZ58,Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein),Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein),GO:0030154; GO:0005814; GO:0007275; GO:0005634,cell differentiation; centriole; multicellular organismal development; nucleus,PF07111;,4.00E-19,CHOYP_CCHCR1.1.1,,,,,,,CCHCR_PONPY,Pongo pygmaeus (Bornean orangutan),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp114977_c0_seq1,705,48.227,0.85608543,0,94,,4.00E-10,P83425,Heavy metal-binding protein HIP,Heavy metal-binding protein HIP,GO:0005576; GO:0046872,extracellular region; metal ion binding,PF00386;,,,,,,,,,HIP_MYTED,Mytilus edulis (Blue mussel), comp114978_c0_seq1,251,61.3546,1.07730848,3,6,,3.00E-10,C1A0S6,ATP-dependent dethiobiotin synthetase BioD (EC 6.3.3.3) (DTB synthetase) (DTBS) (Dethiobiotin synthase),ATP-dependent dethiobiotin synthetase BioD (EC 6.3.3.3) (DTB synthetase) (DTBS) (Dethiobiotin synthase),GO:0005524; GO:0009102; GO:0005737; GO:0004141; GO:0000287,ATP binding; biotin biosynthetic process; cytoplasm; dethiobiotin synthase activity; magnesium ion binding,,,,,,,,,,BIOD_RHOE4,Rhodococcus erythropolis (strain PR4 / NBRC 100887),biotin biosynthetic process [GO:0009102] comp114982_c1_seq1,576,43.2292,0.29838487,27,33,,2.00E-71,Q5RDP4,"Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)","Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)",GO:0005524; GO:0002161; GO:0004823; GO:0006429; GO:0005759; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; leucine-tRNA ligase activity; leucyl-tRNA aminoacylation; mitochondrial matrix; regulation of translational fidelity,PF08264;PF00133;,1.00E-49,CHOYP_LARS2.1.1,,,,,,,SYLM_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),leucyl-tRNA aminoacylation [GO:0006429] comp114987_c0_seq1,316,71.2025,1.12714466,0,19,,2.00E-19,A8GKG7,Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.176) (16S rRNA m5C967 methyltransferase) (rRNA (cytosine-C(5)-)-methyltransferase RsmB),Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.176) (16S rRNA m5C967 methyltransferase) (rRNA (cytosine-C(5)-)-methyltransferase RsmB),GO:0003723; GO:0005737; GO:0016434; GO:0006355,"RNA binding; cytoplasm; rRNA (cytosine) methyltransferase activity; regulation of transcription, DNA-dependent",PF01189;PF01029;,,,,,,,,,RSMB_SERP5,Serratia proteamaculans (strain 568),"regulation of transcription, DNA-templated [GO:0006355]" comp114989_c0_seq1,505,48.3168,0.42166832,28,6,,5.00E-26,Q6A4L1,Solute carrier family 12 member 8,Solute carrier family 12 member 8,GO:0016021; GO:0006813; GO:0015293,integral to membrane; potassium ion transport; symporter activity,PF00324;,3.00E-63,CHOYP_DVIR_GJ19220.1.1,,,,,,,S12A8_XENLA,Xenopus laevis (African clawed frog),potassium ion transport [GO:0006813] comp114991_c0_seq1,449,44.098,0.97413121,12,59,,1.00E-18,Q8TCT0,Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4),Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4),GO:0005524; GO:0003951; GO:0001729; GO:0006672; GO:0005737; GO:0004143; GO:0006687; GO:0016021; GO:0000287; GO:0005739; GO:0005634; GO:0005543; GO:0005886; GO:0007205; GO:0044281,ATP binding; NAD+ kinase activity; ceramide kinase activity; ceramide metabolic process; cytoplasm; diacylglycerol kinase activity; glycosphingolipid metabolic process; integral to membrane; magnesium ion binding; mitochondrion; nucleus; phospholipid binding; plasma membrane; protein kinase C-activating G-protein coupled receptor signaling pathway; small molecule metabolic process,PF00781;,,,,,,,,,CERK1_HUMAN,Homo sapiens (Human),ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687] comp114997_c2_seq1,638,47.1787,0.67714755,8,30,,1.00E-29,Q8WU20,Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1),Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1),GO:0038095; GO:0007186; GO:0000187; GO:0000186; GO:0008595; GO:0012505; GO:0005768; GO:0007173; GO:0008543; GO:0030900; GO:0001702; GO:0045087; GO:0008286; GO:0005887; GO:0007405; GO:0048011; GO:0046619; GO:0001759; GO:0019211; GO:0048015; GO:0060527; GO:0050678; GO:0005068; GO:0007185; GO:0003281,"Fc-epsilon receptor signaling pathway; G-protein coupled receptor signaling pathway; activation of MAPK activity; activation of MAPKK activity; anterior/posterior axis specification, embryo; endomembrane system; endosome; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; forebrain development; gastrulation with mouth forming second; innate immune response; insulin receptor signaling pathway; integral to plasma membrane; neuroblast proliferation; neurotrophin TRK receptor signaling pathway; optic placode formation involved in camera-type eye formation; organ induction; phosphatase activator activity; phosphatidylinositol-mediated signaling; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; regulation of epithelial cell proliferation; transmembrane receptor protein tyrosine kinase adaptor activity; transmembrane receptor protein tyrosine phosphatase signaling pathway; ventricular septum development",PF02174;,4.00E-19,CHOYP_LOC662137.1.1,,,,,,,FRS2_HUMAN,Homo sapiens (Human),"activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; anterior/posterior axis specification, embryo [GO:0008595]; fibroblast growth factor receptor signaling pathway [GO:0008543]; forebrain development [GO:0030900]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; lens fiber cell development [GO:0070307]; MAPK cascade [GO:0000165]; neuroblast proliferation [GO:0007405]; optic placode formation involved in camera-type eye formation [GO:0046619]; organ induction [GO:0001759]; phosphatidylinositol-mediated signaling [GO:0048015]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell proliferation [GO:0050678]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]; ventricular septum development [GO:0003281]" comp115012_c0_seq1,678,41.8879,0.82805058,41,19,,,,,,,,,6.00E-11,CHOYP_LOC100378967.1.1,,,,,,,,, comp115026_c0_seq1,279,30.1075,0,3,0,,,,,,,,,2.00E-12,CHOYP_LOC100891046.2.2,,,,,,,,, comp115026_c0_seq3,380,30.2632,0,0,0,,,,,,,,,8.00E-25,CHOYP_MANSC1.1.1,,,,,,,,, comp115032_c0_seq1,414,51.6908,1.04122471,1,29,,3.00E-21,Q4FZU4,ADAMTS-like protein 4 (ADAMTSL-4),ADAMTS-like protein 4 (ADAMTSL-4),GO:0006915; GO:0030198; GO:0005614; GO:0004222; GO:0043065; GO:0002020,apoptotic process; extracellular matrix organization; interstitial matrix; metalloendopeptidase activity; positive regulation of apoptotic process; protease binding,PF05986;PF08686;PF00090;,,,,,,,,,ATL4_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; positive regulation of apoptotic process [GO:0043065] comp115034_c0_seq1,603,41.6252,0.73479521,17,47,,2.00E-09,P74041,Uncharacterized oxidoreductase sll0816 (EC 1.-.-.-),Uncharacterized oxidoreductase sll0816 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF01408;PF02894;,,,,,,,,,Y816_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),oxidation-reduction process [GO:0055114] comp115034_c1_seq1,478,40.1674,0.65827132,15,34,,6.00E-55,Q6P4M5,Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-),Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF01408;,4.00E-56,CHOYP_BRAFLDRAFT_68464.1.1,,,,,,,GFOD1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),oxidation-reduction process [GO:0055114] comp115046_c0_seq1,831,35.8604,0.6049543,60,705,,1.00E-86,O35165,Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin),Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin),GO:0000139; GO:0005795; GO:0005789; GO:0016021; GO:0015031; GO:0016192,Golgi membrane; Golgi stack; endoplasmic reticulum membrane; integral to membrane; protein transport; vesicle-mediated transport,,8.00E-42,CHOYP_LOC100367873.1.1,,,,,,,GOSR2_RAT,Rattus norvegicus (Rat),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion with Golgi apparatus [GO:0048280]" comp115053_c0_seq1,498,45.1807,0.33546354,3,42,,2.00E-28,Q9QWN8,"Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)","Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)",GO:0051693; GO:0005829; GO:0016363; GO:0005543; GO:0017158; GO:0008091; GO:0005200; GO:0016081,actin filament capping; cytosol; nuclear matrix; phospholipid binding; regulation of calcium ion-dependent exocytosis; spectrin; structural constituent of cytoskeleton; synaptic vesicle docking involved in exocytosis,PF00307;PF00435;,3.00E-76,CHOYP_LOC100377364.1.2,,,,,,,SPTN2_RAT,Rattus norvegicus (Rat),actin filament capping [GO:0051693]; cellular response to ethanol [GO:0071361]; regulation of calcium ion-dependent exocytosis [GO:0017158]; synaptic vesicle docking [GO:0016081]; synaptic vesicle exocytosis [GO:0016079] comp115064_c0_seq1,337,40.3561,0.29468437,19,14,,,,,,,,,,,3.00E-14,ruditapes_c29520,,,,,,, comp115067_c0_seq1,262,41.2214,0.37951491,7,64,,1.00E-27,Q95029,Cathepsin L (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],Cathepsin L (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],GO:0008234; GO:0007586; GO:0045169; GO:0005764; GO:0006508; GO:0035071,cysteine-type peptidase activity; digestion; fusome; lysosome; proteolysis; salivary gland cell autophagic cell death,PF08246;PF00112;,8.00E-17,CHOYP_LOC659226.3.3,9.00E-14,ruditapes_c7023,,,,,CATL_DROME,Drosophila melanogaster (Fruit fly),autophagic cell death [GO:0048102]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; salivary gland cell autophagic cell death [GO:0035071] comp115080_c0_seq2,508,44.4882,0.65440189,0,2,,,,,,,,,2.00E-47,CHOYP_DJC13.1.1,,,,,,,,, comp115080_c0_seq4,872,46.5596,0.70818677,21,31,,1.00E-107,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,3.00E-98,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp115081_c1_seq1,464,42.2414,0.96996696,2,43,,2.00E-14,Q9HBA0,Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC),Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC),GO:0005524; GO:0042169; GO:0031532; GO:0051015; GO:0007015; GO:0043014; GO:0048487; GO:0005262; GO:0070509; GO:0005516; GO:0008219; GO:0006884; GO:0007043; GO:0071476; GO:0034605; GO:0005929; GO:0030864; GO:0043622; GO:0005881; GO:0007204; GO:0030175; GO:0005925; GO:0030426; GO:0042538; GO:0016021; GO:0030027; GO:0008017; GO:0046785; GO:0010977; GO:0005034; GO:0007231; GO:0031117; GO:0005080; GO:0047484; GO:0009612; GO:0032587; GO:0030103,ATP binding; SH2 domain binding; actin cytoskeleton reorganization; actin filament binding; actin filament organization; alpha-tubulin binding; beta-tubulin binding; calcium channel activity; calcium ion import; calmodulin binding; cell death; cell volume homeostasis; cell-cell junction assembly; cellular hypotonic response; cellular response to heat; cilium; cortical actin cytoskeleton; cortical microtubule organization; cytoplasmic microtubule; elevation of cytosolic calcium ion concentration; filopodium; focal adhesion; growth cone; hyperosmotic salinity response; integral to membrane; lamellipodium; microtubule binding; microtubule polymerization; negative regulation of neuron projection development; osmosensor activity; osmosensory signaling pathway; positive regulation of microtubule depolymerization; protein kinase C binding; regulation of response to osmotic stress; response to mechanical stimulus; ruffle membrane; vasopressin secretion,PF00023;PF00520;,,,,,,,,,TRPV4_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actin filament organization [GO:0007015]; blood vessel endothelial cell delamination [GO:0097497]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell-cell junction assembly [GO:0007043]; cellular calcium ion homeostasis [GO:0006874]; cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; cellular response to heat [GO:0034605]; cellular response to osmotic stress [GO:0071470]; cell volume homeostasis [GO:0006884]; cortical microtubule organization [GO:0043622]; diet induced thermogenesis [GO:0002024]; glucose homeostasis [GO:0042593]; hyperosmotic salinity response [GO:0042538]; microtubule polymerization [GO:0046785]; multicellular organismal water homeostasis [GO:0050891]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osmosensory signaling pathway [GO:0007231]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000340]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of energy homeostasis [GO:2000507]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage inflammatory protein 1 alpha production [GO:0071642]; positive regulation of microtubule depolymerization [GO:0031117]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of vascular permeability [GO:0043117]; regulation of response to osmotic stress [GO:0047484]; response to insulin [GO:0032868]; response to mechanical stimulus [GO:0009612]; signal transduction involved in regulation of aerobic respiration [GO:1903759]; vasopressin secretion [GO:0030103] comp115084_c0_seq2,922,43.3839,0.42491099,20,14,,8.00E-17,Q7Z2W4,Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP),Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP),GO:0005794; GO:0003950; GO:0003723; GO:0071360; GO:0005737; GO:0051607; GO:0045087; GO:0046872; GO:0045071; GO:0005634; GO:0005886; GO:0043123; GO:1900246; GO:0032727; GO:0032728; GO:0061014; GO:0032481; GO:0009615,Golgi apparatus; NAD+ ADP-ribosyltransferase activity; RNA binding; cellular response to exogenous dsRNA; cytoplasm; defense response to virus; innate immune response; metal ion binding; negative regulation of viral genome replication; nucleus; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of RIG-I signaling pathway; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of mRNA catabolic process; positive regulation of type I interferon production; response to virus,PF00644;PF02825;,,,,,,,,,ZCCHV_HUMAN,Homo sapiens (Human),cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]; suppression by virus of host molecular function [GO:0039507] comp115089_c0_seq1,810,43.7037,0.54502771,2,0,,2.00E-16,Q96NG8,Zinc finger protein 582,Zinc finger protein 582,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN582_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp115089_c0_seq2,866,43.9954,0.47956256,6,0,,4.00E-19,Q6ZSB9,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp115100_c0_seq2,489,48.2618,0.5104188,12,37,,5.00E-15,Q13395,Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185),Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185),GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0005634; GO:0006357,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; nucleus; regulation of transcription from RNA polymerase II promoter,PF00588;,,,,,,,,,TARB1_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357]; tRNA methylation [GO:0030488] comp115102_c0_seq1,251,46.2151,0.70435901,0,0,,6.00E-34,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,,,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp115102_c0_seq2,1231,47.3599,0.46876443,15,7,,6.00E-166,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,0,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp115124_c0_seq1,641,40.5616,0.68395053,27,10,,2.00E-14,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp115136_c1_seq1,456,42.9825,0.60131868,9,93,,1.00E-65,Q8BTZ7,Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta),Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta),GO:0009298; GO:0005525; GO:0004475; GO:0005739,GDP-mannose biosynthetic process; GTP binding; mannose-1-phosphate guanylyltransferase activity; mitochondrion,PF00132;PF00483;,2.00E-53,CHOYP_NEMVEDRAFT_V1G162365.1.1,,,,,,,GMPPB_MOUSE,Mus musculus (Mouse),GDP-mannose biosynthetic process [GO:0009298] comp115139_c0_seq4,697,41.6069,0.55370572,52,16,,1.00E-08,P30352,"Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)","Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)",GO:0003723; GO:0008380; GO:0006397; GO:0000166; GO:0005634,RNA binding; RNA splicing; mRNA processing; nucleotide binding; nucleus,PF00076;,,,,,,,,,SRSF2_CHICK,Gallus gallus (Chicken),"mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" comp115159_c0_seq1,982,40.5295,0.49725625,38,34,,1.00E-14,Q9C0K0,B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1),B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1),GO:0000978; GO:0001077; GO:0033077; GO:0033153; GO:0046632; GO:0003382; GO:0003334; GO:0046872; GO:0043066; GO:0008285; GO:0005634; GO:0042475; GO:0071678; GO:0043368; GO:0045944; GO:0031077; GO:0010837; GO:0019216; GO:0045664; GO:0021773; GO:0048538,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; T cell differentiation in thymus; T cell receptor V(D)J recombination; alpha-beta T cell differentiation; epithelial cell morphogenesis; keratinocyte development; metal ion binding; negative regulation of apoptotic process; negative regulation of cell proliferation; nucleus; odontogenesis of dentin-containing tooth; olfactory bulb axon guidance; positive T cell selection; positive regulation of transcription from RNA polymerase II promoter; post-embryonic camera-type eye development; regulation of keratinocyte proliferation; regulation of lipid metabolic process; regulation of neuron differentiation; striatal medium spiny neuron differentiation; thymus development,PF00096;,3.00E-17,CHOYP_YTDC2.1.1,,,,,,,BC11B_HUMAN,Homo sapiens (Human),alpha-beta T cell differentiation [GO:0046632]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; neurogenesis [GO:0022008]; odontogenesis of dentin-containing tooth [GO:0042475]; olfactory bulb axon guidance [GO:0071678]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive T cell selection [GO:0043368]; post-embryonic camera-type eye development [GO:0031077]; regulation of keratinocyte proliferation [GO:0010837]; regulation of lipid metabolic process [GO:0019216]; regulation of neuron differentiation [GO:0045664]; signal transduction [GO:0007165]; striatal medium spiny neuron differentiation [GO:0021773]; T cell differentiation in thymus [GO:0033077]; T cell receptor V(D)J recombination [GO:0033153]; thymus development [GO:0048538] comp115163_c0_seq1,416,44.7115,0.33749761,3,0,,,,,,,,,5.00E-15,CHOYP_LOC580904.1.1,,,,,,,,, comp115163_c0_seq2,450,52,0.39607924,13,15,,,,,,,,,2.00E-15,CHOYP_BRAFLDRAFT_69981.1.1,,,,,,,,, comp115168_c0_seq1,265,43.7736,0.79097172,29,0,,4.00E-08,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp115172_c0_seq1,1540,39.8052,0.48548635,56,24,,1.00E-70,Q6DKB0,Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II),Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II),GO:0008253; GO:0005737; GO:0046872; GO:0000166; GO:0009117,5'-nucleotidase activity; cytoplasm; metal ion binding; nucleotide binding; nucleotide metabolic process,PF05761;,7.00E-52,CHOYP_LOC100642349.1.1,,,,,,,5NTC_XENLA,Xenopus laevis (African clawed frog),nucleotide metabolic process [GO:0009117] comp115191_c0_seq1,700,45.4286,0.86536494,0,0,,3.00E-35,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,7.00E-23,CHOYP_BRAFLDRAFT_57788.4.10,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp115191_c0_seq3,843,37.7224,0.94831594,3,2,,,,,,,,,1.00E-13,CHOYP_LOC100533316.2.2,,,,,,,,, comp115191_c0_seq4,700,45.1429,0.88326807,5,16,,8.00E-40,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,7.00E-23,CHOYP_BRAFLDRAFT_57788.4.10,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp115210_c0_seq1,576,41.3194,0.70386263,2,0,,7.00E-09,Q9HCE9,Anoctamin-8 (Transmembrane protein 16H),Anoctamin-8 (Transmembrane protein 16H),GO:0016021; GO:0005622; GO:0034220; GO:0005886,integral to membrane; intracellular; ion transmembrane transport; plasma membrane,PF04547;,,,,,,,,,ANO8_HUMAN,Homo sapiens (Human),chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220] comp115210_c0_seq2,879,42.2071,0.72985876,19,12,,1.00E-79,Q8C5H1,Anoctamin-4 (Transmembrane protein 16D),Anoctamin-4 (Transmembrane protein 16D),GO:0016021; GO:0005622; GO:0005886,integral to membrane; intracellular; plasma membrane,PF16178;PF04547;,9.00E-80,CHOYP_TMEM16.1.2,,,,,,,ANO4_MOUSE,Mus musculus (Mouse),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821] comp115210_c1_seq1,734,42.2343,0.55254028,34,60,,6.00E-33,A1A5B4,Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein),Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein),GO:0016021; GO:0005622; GO:0034220; GO:0005886,integral to membrane; intracellular; ion transmembrane transport; plasma membrane,PF04547;,,,,,,,,,ANO9_HUMAN,Homo sapiens (Human),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; negative regulation of intracellular calcium activated chloride channel activity [GO:1902939] comp115224_c0_seq1,591,40.2707,0.72216051,25,29,,4.00E-29,Q8K2W6,PHD finger protein 13,PHD finger protein 13,GO:0051301; GO:0003682; GO:0016568; GO:0007076; GO:0005654; GO:0005634; GO:0008270,cell division; chromatin binding; chromatin modification; mitotic chromosome condensation; nucleoplasm; nucleus; zinc ion binding,PF00628;,3.00E-20,CHOYP_LOC100369478.1.1,,,,,,,PHF13_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; chromatin modification [GO:0016568]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076] comp115230_c0_seq1,488,44.0574,0.36042164,11,32,,5.00E-45,Q9WVD5,Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15),Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15),GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,,,,,,,,,ORNT1_MOUSE,Mus musculus (Mouse),translation [GO:0006412] comp115230_c1_seq1,212,37.7358,0,0,13,,3.00E-07,Q8BZ09,Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21),Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21),GO:0016021; GO:0005743; GO:0005739; GO:0006810,integral to membrane; mitochondrial inner membrane; mitochondrion; transport,PF00153;,,,,,,,,,ODC_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transport [GO:0006810] comp115235_c0_seq1,579,50.4318,0.97973265,15,41,,2.00E-65,Q03347,Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit),Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit),GO:0005524; GO:0003677; GO:0005604; GO:0048266; GO:0007417; GO:0060216; GO:0035162; GO:0031069; GO:0001701; GO:0001889; GO:0002318; GO:0048666; GO:0005634; GO:0045766; GO:0030854; GO:0045944; GO:0071336; GO:0009966; GO:0032526; GO:0003700; GO:0001501; GO:0006351,"ATP binding; DNA binding; basement membrane; behavioral response to pain; central nervous system development; definitive hemopoiesis; embryonic hemopoiesis; hair follicle morphogenesis; in utero embryonic development; liver development; myeloid progenitor cell differentiation; neuron development; nucleus; positive regulation of angiogenesis; positive regulation of granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of hair follicle cell proliferation; regulation of signal transduction; response to retinoic acid; sequence-specific DNA binding transcription factor activity; skeletal system development; transcription, DNA-dependent",PF00853;PF08504;,1.00E-50,CHOYP_RUNX1.1.1,,,,,,,RUNX1_MOUSE,Mus musculus (Mouse),"behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of cell proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; ossification [GO:0001503]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]" comp115239_c0_seq1,1035,42.1256,0.35092655,55,42,,1.00E-89,P37892,Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase),Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase),GO:0005576; GO:0004181; GO:0006508; GO:0030658; GO:0008270,extracellular region; metallocarboxypeptidase activity; proteolysis; transport vesicle membrane; zinc ion binding,PF00246;,2.00E-13,CHOYP_LOC100533325.1.1,,,,,,,CBPE_LOPAM,Lophius americanus (American angler) (Anglerfish), comp115243_c0_seq2,930,43.7634,0.65338152,19,19,,2.00E-20,Q9P267,Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5),Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5),GO:0003682; GO:0005694; GO:0005634,chromatin binding; chromosome; nucleus,PF00855;,,,,,,,,,MBD5_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nervous system development [GO:0007399]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; regulation of multicellular organism growth [GO:0040014]; single-organism behavior [GO:0044708]; xenophagy [GO:0098792] comp115244_c0_seq2,451,41.9069,0.4565679,17,20,,6.00E-30,Q14149,MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled-coil domain protein 3),MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3),GO:0005524; GO:0016605; GO:0016235; GO:0007569; GO:0045111; GO:0051457; GO:0048147; GO:0018105; GO:0009791; GO:0050821; GO:0008270,ATP binding; PML body; aggresome; cell aging; intermediate filament cytoskeleton; maintenance of protein location in nucleus; negative regulation of fibroblast proliferation; peptidyl-serine phosphorylation; post-embryonic development; protein stabilization; zinc ion binding,PF07496;,,,,,,,,,MORC3_HUMAN,Homo sapiens (Human),cell aging [GO:0007569]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-serine phosphorylation [GO:0018105]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; viral process [GO:0016032] comp115252_c0_seq1,472,43.0085,0.2790573,7,75,,1.00E-30,Q8N3P4,Vacuolar protein sorting-associated protein 8 homolog,Vacuolar protein sorting-associated protein 8 homolog,GO:0008270,zinc ion binding,PF12816;,5.00E-42,CHOYP_VPS8.1.1,,,,,,,VPS8_HUMAN,Homo sapiens (Human),endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031] comp115260_c1_seq1,717,44.9093,0.62324051,0,0,,8.00E-43,Q8MQJ9,Brain tumor protein,Brain tumor protein,GO:0008356; GO:0055060; GO:0007411; GO:0007420; GO:0005737; GO:0007402; GO:0007406; GO:0048477; GO:0006909; GO:0009303; GO:0035282; GO:0030371; GO:0008270,asymmetric cell division; asymmetric neuroblast division resulting in ganglion mother cell formation; axon guidance; brain development; cytoplasm; ganglion mother cell fate determination; negative regulation of neuroblast proliferation; oogenesis; phagocytosis; rRNA transcription; segmentation; translation repressor activity; zinc ion binding,PF01436;PF00643;,,,,,,,,,BRAT_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419] comp115260_c1_seq2,1534,43.9374,0.70293197,52,96,,2.00E-61,P34611,B-box type zinc finger protein ncl-1,B-box type zinc finger protein ncl-1,GO:0005737; GO:0090071; GO:0008270,cytoplasm; negative regulation of ribosome biogenesis; zinc ion binding,PF01436;PF00643;,8.00E-121,CHOYP_LOC100902046.1.1,,,,,,,NCL1_CAEEL,Caenorhabditis elegans,negative regulation of ribosome biogenesis [GO:0090071] comp115265_c0_seq1,644,44.0994,0.50899744,39,52,,2.00E-76,Q01406,Src substrate protein p85 (Cortactin) (p80),Src substrate protein p85 (Cortactin) (p80),GO:0005856; GO:0043197; GO:0005783; GO:0030027; GO:0005886; GO:0001726,cytoskeleton; dendritic spine; endoplasmic reticulum; lamellipodium; plasma membrane; ruffle,PF02218;PF14604;,3.00E-90,CHOYP_SRC8.1.1,,,,,,,SRC8_CHICK,Gallus gallus (Chicken),actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; cell motility [GO:0048870]; focal adhesion assembly [GO:0048041]; intracellular protein transport [GO:0006886]; lamellipodium organization [GO:0097581]; neuron projection morphogenesis [GO:0048812]; positive regulation of actin filament polymerization [GO:0030838]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516] comp115280_c0_seq1,1253,36.0734,0.29770332,23,95,,6.00E-10,Q6ULP2,Aftiphilin,Aftiphilin,GO:0030121; GO:0030276; GO:0005829; GO:0005634; GO:0015031,AP-1 adaptor complex; clathrin binding; cytosol; nucleus; protein transport,PF15045;,,,,,,,,,AFTIN_HUMAN,Homo sapiens (Human),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp115280_c0_seq2,627,40.8293,0.30694115,0,0,,1.00E-10,Q6ULP2,Aftiphilin,Aftiphilin,GO:0030121; GO:0030276; GO:0005829; GO:0005634; GO:0015031,AP-1 adaptor complex; clathrin binding; cytosol; nucleus; protein transport,PF15045;,,,,,,,,,AFTIN_HUMAN,Homo sapiens (Human),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp115284_c0_seq1,462,42.4242,0.34449566,14,37,,,,,,,,,,,5.00E-14,ruditapes_c20090,,,,,,, comp115294_c0_seq1,207,29.4686,0.44828632,4,0,,1.00E-07,Q8I8U7,Transcription-associated protein 1 (dTRA1),Transcription-associated protein 1 (dTRA1),GO:0035267; GO:0000124; GO:0005737; GO:0016573; GO:0043486; GO:0005875; GO:0006909; GO:0016773; GO:0005703; GO:0045747; GO:0006355; GO:0006351; GO:0035222,"NuA4 histone acetyltransferase complex; SAGA complex; cytoplasm; histone acetylation; histone exchange; microtubule associated complex; phagocytosis; phosphotransferase activity, alcohol group as acceptor; polytene chromosome puff; positive regulation of Notch signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; wing disc pattern formation",PF02259;PF02260;PF00454;,2.00E-11,CHOYP_LOC100123553.1.1,,,,,,,TRA1_DROME,Drosophila melanogaster (Fruit fly),"DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H3 acetylation [GO:0043966]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]" comp115298_c0_seq1,518,38.417,0.26323896,12,26,,5.00E-12,Q8IWU2,Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2),Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2),GO:0005524; GO:0005794; GO:0005769; GO:0045022; GO:0032456; GO:0016021; GO:0018105; GO:0018107; GO:0018108; GO:0048471; GO:0046777; GO:0004864; GO:0004674; GO:0004713; GO:0001881; GO:0055037; GO:0033572,ATP binding; Golgi apparatus; early endosome; early endosome to late endosome transport; endocytic recycling; integral to membrane; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; peptidyl-tyrosine phosphorylation; perinuclear region of cytoplasm; protein autophosphorylation; protein phosphatase inhibitor activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; receptor recycling; recycling endosome; transferrin transport,PF07714;,,,,,,,,,LMTK2_HUMAN,Homo sapiens (Human),early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor recycling [GO:0001881]; transferrin transport [GO:0033572] comp115308_c0_seq1,801,43.6954,0.78875025,4,260,,9.00E-21,Q6IRB2,Transcription factor HES-1-A (Hairy and enhancer of split 1-A) (Protein hairy-1) (Xhairy-1) (Xhairy1) (Xlh1),Transcription factor HES-1-A (Hairy and enhancer of split 1-A) (Protein hairy-1) (Xhairy-1) (Xhairy1) (Xlh1),GO:0007219; GO:0007275; GO:0048635; GO:0000122; GO:0005634; GO:0043565; GO:0006351,"Notch signaling pathway; multicellular organismal development; negative regulation of muscle organ development; negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding; transcription, DNA-dependent",PF07527;PF00010;,,,,,,,,,HES1A_XENLA,Xenopus laevis (African clawed frog),"multicellular organism development [GO:0007275]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; transcription, DNA-templated [GO:0006351]" comp115314_c1_seq2,1021,40.8423,1.08532748,10,32,,9.00E-07,O15403,Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6),Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT7_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp115315_c1_seq1,355,43.9437,0.2926211,18,0,,3.00E-11,Q9BYK8,"Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)","Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)",GO:0005524; GO:0003677; GO:0044255; GO:0004386; GO:0030374; GO:0046872; GO:0005654; GO:0045944; GO:0044281; GO:0006351,"ATP binding; DNA binding; cellular lipid metabolic process; helicase activity; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; transcription, DNA-dependent",,,,,,,,,,PR285_HUMAN,Homo sapiens (Human),"cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp115318_c0_seq1,1213,43.0338,0.59399551,85,44,,1.00E-78,Q6NUP7,Serine/threonine-protein phosphatase 4 regulatory subunit 4,Serine/threonine-protein phosphatase 4 regulatory subunit 4,GO:0005737; GO:0032515; GO:0019888; GO:0008287; GO:0080163,cytoplasm; negative regulation of phosphoprotein phosphatase activity; protein phosphatase regulator activity; protein serine/threonine phosphatase complex; regulation of protein serine/threonine phosphatase activity,,9.00E-31,CHOYP_PPP4R4.3.3,,,,,,,PP4R4_HUMAN,Homo sapiens (Human),negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163] comp115322_c0_seq1,399,41.3534,0.41691745,4,73,,6.00E-35,Q9NRN7,L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.-) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog),L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.-) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog),GO:0005829; GO:0008897; GO:0009059; GO:0000287; GO:0015939,cytosol; holo-[acyl-carrier-protein] synthase activity; macromolecule biosynthetic process; magnesium ion binding; pantothenate metabolic process,PF01648;,,,,,,,,,ADPPT_HUMAN,Homo sapiens (Human),lysine biosynthetic process via aminoadipic acid [GO:0019878]; pantothenate metabolic process [GO:0015939] comp115325_c1_seq1,492,46.3415,0.46436613,18,36,,1.00E-44,Q5ZMQ9,Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1),Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1),GO:0005829; GO:0005778; GO:0005052; GO:0016560,"cytosol; peroxisomal membrane; peroxisome matrix targeting signal-1 binding; protein import into peroxisome matrix, docking",,4.00E-55,CHOYP_PEX5.2.2,,,,,,,PEX5_CHICK,Gallus gallus (Chicken),"protein import into peroxisome matrix, docking [GO:0016560]" comp115325_c2_seq1,254,45.6693,0.48296203,3,15,,2.00E-24,O74711,Peroxisomal targeting signal receptor (PTS1 receptor) (PTS1R) (Peroxin-5),Peroxisomal targeting signal receptor (PTS1 receptor) (PTS1R) (Peroxin-5),GO:0035690; GO:0005829; GO:0006635; GO:0044182; GO:1900429; GO:0000122; GO:0009405; GO:0005778; GO:0005052; GO:0030674; GO:0016560; GO:0003714; GO:0017053,"cellular response to drug; cytosol; fatty acid beta-oxidation; filamentous growth of a population of unicellular organisms; negative regulation of filamentous growth of a population of unicellular organisms; negative regulation of transcription from RNA polymerase II promoter; pathogenesis; peroxisomal membrane; peroxisome matrix targeting signal-1 binding; protein binding, bridging; protein import into peroxisome matrix, docking; transcription corepressor activity; transcriptional repressor complex",,,,,,,,,,PEX5_CANAL,Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast),"fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein targeting to peroxisome [GO:0006625]" comp115327_c0_seq1,1059,44.6648,0.79605264,85,29,,9.00E-09,Q01664,Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41),Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41),GO:0006978; GO:0070888; GO:0003705; GO:0071549; GO:0043922; GO:0043392; GO:0043066; GO:0071157; GO:0008285; GO:0045736; GO:0045892; GO:0043923; GO:0043065; GO:0045893; GO:0006461; GO:0043565; GO:0017053,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; E-box binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; cellular response to dexamethasone stimulus; negative regulation by host of viral transcription; negative regulation of DNA binding; negative regulation of apoptotic process; negative regulation of cell cycle arrest; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of transcription, DNA-dependent; positive regulation by host of viral transcription; positive regulation of apoptotic process; positive regulation of transcription, DNA-dependent; protein complex assembly; sequence-specific DNA binding; transcriptional repressor complex",PF00010;,1.00E-16,CHOYP_CEG1A.2.6,,,,,,,TFAP4_HUMAN,Homo sapiens (Human),"cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex assembly [GO:0006461]" comp115329_c1_seq1,533,44.6529,0.4308994,22,5,,6.00E-49,Q5SUV1,"Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (EC 1.3.99.-) (Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1)","Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (EC 1.3.99.-) (Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1)",GO:0051539; GO:0004109; GO:0046872; GO:0005739; GO:0006779,"4 iron, 4 sulfur cluster binding; coproporphyrinogen oxidase activity; metal ion binding; mitochondrion; porphyrin-containing compound biosynthetic process",PF06969;PF04055;,,,,,,,,,RSAD1_MOUSE,Mus musculus (Mouse),porphyrin-containing compound biosynthetic process [GO:0006779] comp115339_c1_seq1,1631,46.9651,0.57246244,77,93,,0,Q9V9J3,Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41),Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41),GO:0005524; GO:0007254; GO:0051017; GO:0005912; GO:0034332; GO:0043277; GO:0048749; GO:0007395; GO:0090136; GO:0046529; GO:0007476; GO:0042059; GO:0045886; GO:0004715; GO:0007424; GO:0004713; GO:0007435; GO:0007169; GO:0006099,"ATP binding; JNK cascade; actin filament bundle assembly; adherens junction; adherens junction organization; apoptotic cell clearance; compound eye development; dorsal closure, spreading of leading edge cells; epithelial cell-cell adhesion; imaginal disc fusion, thorax closure; imaginal disc-derived wing morphogenesis; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of synaptic growth at neuromuscular junction; non-membrane spanning protein tyrosine kinase activity; open tracheal system development; protein tyrosine kinase activity; salivary gland morphogenesis; transmembrane receptor protein tyrosine kinase signaling pathway; tricarboxylic acid cycle",PF07714;PF00017;PF00018;,0,CHOYP_SRC2.1.1,,,,,,,SRC42_DROME,Drosophila melanogaster (Fruit fly),"actin filament bundle assembly [GO:0051017]; adherens junction organization [GO:0034332]; apoptotic cell clearance [GO:0043277]; axon guidance [GO:0007411]; cell migration [GO:0016477]; compound eye development [GO:0048749]; defense response to bacterium [GO:0042742]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; epithelial cell-cell adhesion [GO:0090136]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc fusion, thorax closure [GO:0046529]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; JNK cascade [GO:0007254]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; open tracheal system development [GO:0007424]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; salivary gland morphogenesis [GO:0007435]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tricarboxylic acid cycle [GO:0006099]" comp115353_c0_seq1,714,45.7983,0.75484651,7,0,,1.00E-65,Q9UPU5,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP24_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp115353_c0_seq2,631,47.8605,0.69735798,0,0,,,,,,,,,3.00E-27,CHOYP_LOC592001.1.1,,,,,,,,, comp115359_c0_seq2,693,37.6623,0.62380283,0,10,,,,,,,,,6.00E-68,CHOYP_MTSS1.5.5,,,,,,,,, comp115359_c0_seq3,787,38.7548,0.58769947,5,9,,1.00E-72,O43312,Metastasis suppressor protein 1 (Metastasis suppressor YGL-1) (Missing in metastasis protein),Metastasis suppressor protein 1 (Metastasis suppressor YGL-1) (Missing in metastasis protein),GO:0015629; GO:0030036; GO:0030041; GO:0003785; GO:0007155; GO:0006928; GO:0071498; GO:0030139; GO:2001013; GO:0046847; GO:0072102; GO:0030035; GO:0050680; GO:0072160; GO:0001726; GO:0007169,actin cytoskeleton; actin cytoskeleton organization; actin filament polymerization; actin monomer binding; cell adhesion; cellular component movement; cellular response to fluid shear stress; endocytic vesicle; epithelial cell proliferation involved in renal tubule morphogenesis; filopodium assembly; glomerulus morphogenesis; microspike assembly; negative regulation of epithelial cell proliferation; nephron tubule epithelial cell differentiation; ruffle; transmembrane receptor protein tyrosine kinase signaling pathway,PF08397;PF02205;,1.00E-76,CHOYP_MTSS1.5.5,,,,,,,MTSS1_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cellular response to fluid shear stress [GO:0071498]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; glomerulus morphogenesis [GO:0072102]; microspike assembly [GO:0030035]; movement of cell or subcellular component [GO:0006928]; negative regulation of epithelial cell proliferation [GO:0050680]; nephron tubule epithelial cell differentiation [GO:0072160]; plasma membrane organization [GO:0007009]; positive regulation of defense response to virus by host [GO:0002230]; renal tubule morphogenesis [GO:0061333]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; xenophagy [GO:0098792] comp115381_c0_seq1,603,44.4444,0.57184385,18,40,,1.00E-18,Q17QV9,Serine/threonine-protein kinase 40 (EC 2.7.11.1),Serine/threonine-protein kinase 40 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0005634; GO:0004674,ATP binding; cytoplasm; nucleus; protein serine/threonine kinase activity,PF00069;,,,1.00E-29,ruditapes_c21684,,,,,STK40_BOVIN,Bos taurus (Bovine),glycogen metabolic process [GO:0005977]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; regulation of gene expression [GO:0010468]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016] comp115387_c0_seq1,659,42.4886,1.00195416,28,16,,3.00E-28,Q8VHR0,Protocadherin 18,Protocadherin 18,GO:0007420; GO:0005509; GO:0016339; GO:0007156; GO:0005887,brain development; calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to plasma membrane,PF00028;PF08266;,,,,,,,,,PCD18_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp115387_c1_seq1,224,35.7143,0.70357875,9,0,,2.00E-11,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp115387_c2_seq1,291,35.3952,0.56241034,10,0,,2.00E-16,Q8TAB3,Protocadherin-19,Protocadherin-19,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;,,,,,,,,,PCD19_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp115392_c0_seq1,340,39.1176,0.23431261,12,7,,2.00E-15,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,7.00E-19,CHOYP_contig_006627,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp115395_c0_seq1,664,43.0723,0.85623925,1,243,female>male,2.00E-23,P82596,Perlucin,Perlucin,GO:0030246,carbohydrate binding,PF00059;,,,,,,,,,PLC_HALLA,Haliotis laevigata (Abalone), comp115396_c0_seq1,306,42.4837,0.3837541,6,24,,5.00E-23,Q8VD04,GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein),GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein),GO:0005769,early endosome,,1.00E-39,CHOYP_GRAP1.1.1,7.00E-48,ruditapes_c13486,,,,,GRAP1_MOUSE,Mus musculus (Mouse), comp115397_c1_seq1,559,41.3238,0.13293285,16,13,,3.00E-48,A6QLY2,Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9),Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9),GO:0005576; GO:0004602; GO:0006979,extracellular region; glutathione peroxidase activity; response to oxidative stress,PF00255;,4.00E-25,CHOYP_BRAFLDRAFT_275043.1.1,,,,,,,GPX7_BOVIN,Bos taurus (Bovine),response to oxidative stress [GO:0006979] comp115403_c0_seq1,202,36.1386,0.15240614,4,3,,2.00E-08,Q6NQ88,Protein DAMAGED DNA-BINDING 2 (UV-damaged DNA-binding protein 2),Protein DAMAGED DNA-BINDING 2 (UV-damaged DNA-binding protein 2),GO:0080008; GO:0003677; GO:0006281; GO:0005634; GO:0016567; GO:0010224; GO:0008270,Cul4-RING ubiquitin ligase complex; DNA binding; DNA repair; nucleus; protein ubiquitination; response to UV-B; zinc ion binding,PF00400;,,,,,,,,,DDB2_ARATH,Arabidopsis thaliana (Mouse-ear cress),DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; response to UV-B [GO:0010224] comp115403_c1_seq1,500,48.6,0.47746957,0,0,,5.00E-22,Q4KLQ5,WD repeat-containing protein 76,WD repeat-containing protein 76,,,,,,,,,,,,WDR76_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974] comp115403_c1_seq2,475,42.3158,0.76404833,4,7,,8.00E-25,B2KIQ4,WD repeat-containing protein 76,WD repeat-containing protein 76,,,,,,,,,,,,WDR76_RHIFE,Rhinolophus ferrumequinum (Greater horseshoe bat),cellular response to DNA damage stimulus [GO:0006974] comp115403_c1_seq3,835,46.2275,0.53866057,1,4,,3.00E-44,Q4KLQ5,WD repeat-containing protein 76,WD repeat-containing protein 76,,,,,,,,,,,,WDR76_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974] comp115415_c0_seq1,680,37.3529,0.34822702,25,33,,1.00E-60,Q6ZQ82,Rho GTPase-activating protein 26 (Rho-type GTPase-activating protein 26),Rho GTPase-activating protein 26 (Rho-type GTPase-activating protein 26),GO:0005096; GO:0005737; GO:0005856; GO:0046847; GO:0005925; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; cytoskeleton; filopodium assembly; focal adhesion; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00169;PF00620;PF14604;,1.00E-70,CHOYP_LOC100749296.1.1,3.00E-13,ruditapes_c28309,,,,,RHG26_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp115420_c0_seq1,341,43.4018,0.43790389,7,27,,3.00E-07,P17421,"Probable fimbrial assembly protein FimD, serogroup H1","Probable fimbrial assembly protein FimD, serogroup H1",,,PF00144;,,,,,,,,,FIMDH_DICNO,Dichelobacter nodosus (Bacteroides nodosus), comp115433_c0_seq1,1010,40.396,1.09254454,15,18,,6.00E-10,A4IIF2,Solute carrier family 26 member 9 (Anion transporter/exchanger protein 9),Solute carrier family 26 member 9 (Anion transporter/exchanger protein 9),GO:0016021; GO:0008271; GO:0008272,integral to membrane; secondary active sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391] comp115433_c0_seq3,722,43.6288,1.15259377,5,20,,3.00E-11,Q9BEG8,Sulfate transporter (Solute carrier family 26 member 2),Sulfate transporter (Solute carrier family 26 member 2),GO:0016021; GO:0008271; GO:0008272,integral to membrane; secondary active sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A2_BOVIN,Bos taurus (Bovine),bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; ossification [GO:0001503]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391] comp115445_c0_seq1,568,47.1831,0.86959006,19,24,,1.00E-32,Q8IZA0,Dyslexia-associated protein KIAA0319-like protein,Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR),GO:0031410; GO:0016021,cytoplasmic vesicle; integral to membrane,,,,,,,,,,K319L_HUMAN,Homo sapiens (Human), comp115446_c0_seq1,1359,44.518,0.56763793,41,119,,6.00E-85,Q9BZF1,Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8),Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8),GO:0015485; GO:0045444; GO:0006869; GO:0010891; GO:0005543,cholesterol binding; fat cell differentiation; lipid transport; negative regulation of sequestering of triglyceride; phospholipid binding,PF01237;PF00169;,6.00E-116,CHOYP_OSBPL8.1.1,,,,,,,OSBL8_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] comp115452_c1_seq1,268,48.5075,0.70053059,0,2,,3.00E-13,Q3UQ22,Netrin-5 (Netrin-1-like protein),Netrin-5 (Netrin-1-like protein),GO:0005576,extracellular region,PF00053;PF01759;,,,,,,,,,NET5_MOUSE,Mus musculus (Mouse), comp115452_c3_seq1,620,52.0968,1.04594867,9,22,,9.00E-102,Q90922,Netrin-1,Netrin-1,GO:0071944; GO:0005578,cell periphery; proteinaceous extracellular matrix,PF00053;PF00055;PF01759;,4.00E-63,CHOYP_NTN1.1.1,,,,,,,NET1_CHICK,Gallus gallus (Chicken),"anterior/posterior axon guidance [GO:0033564]; Cdc42 protein signal transduction [GO:0032488]; establishment of nucleus localization [GO:0040023]; inner ear morphogenesis [GO:0042472]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of cell proliferation [GO:0008284]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; single organismal cell-cell adhesion [GO:0016337]; substrate-dependent cell migration, cell extension [GO:0006930]" comp11545_c0_seq1,218,47.2477,1.12000783,1,0,,3.00E-17,A8CEP3,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,3.00E-15,CHOYP_CALM.23.50,1.00E-16,ruditapes_c19922,,,,,CALM_SACJA,Saccharina japonica (Sweet kelp) (Laminaria japonica), comp115465_c0_seq2,704,45.3125,1.03274419,40,0,,8.00E-28,Q9ES88,Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00939;,4.00E-26,CHOYP_LOC100692894.1.1,,,,,,,S13A2_MOUSE,Mus musculus (Mouse), comp115472_c0_seq2,1076,42.4721,0.35297891,36,21,,3.00E-50,Q6GLL2,Monoacylglycerol lipase abhd6-A (EC 3.1.1.23) (Abhydrolase domain-containing protein 6-A),Monoacylglycerol lipase abhd6-A (EC 3.1.1.23) (Abhydrolase domain-containing protein 6-A),GO:0047372; GO:0016021,acylglycerol lipase activity; integral to membrane,PF00561;,3.00E-11,CHOYP_ABH6B.1.1,,,,,,,ABH6A_XENLA,Xenopus laevis (African clawed frog),acylglycerol catabolic process [GO:0046464] comp115481_c0_seq1,337,40.3561,0.66145397,2,22,,6.00E-16,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp115487_c0_seq1,601,45.7571,0.77278776,0,4,,1.00E-29,Q8JG38,Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1),Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1),GO:0005524; GO:0005794; GO:0006915; GO:0016023; GO:0048701; GO:0005007; GO:0016021; GO:0018108; GO:0005886; GO:0008284,ATP binding; Golgi apparatus; apoptotic process; cytoplasmic membrane-bounded vesicle; embryonic cranial skeleton morphogenesis; fibroblast growth factor-activated receptor activity; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of cell proliferation,PF07679;PF07714;,,,,,,,,,FGFR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; cell proliferation in midbrain [GO:0033278]; cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; digestive tract development [GO:0048565]; midbrain development [GO:0030901]; positive regulation of cell proliferation [GO:0008284] comp115487_c0_seq2,641,44.7738,0.69748318,4,5,,5.00E-25,Q90330,Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase),Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase),GO:0005524; GO:0005783; GO:0005768; GO:0005007; GO:0016021; GO:0018108; GO:0005886; GO:0008284,ATP binding; endoplasmic reticulum; endosome; fibroblast growth factor-activated receptor activity; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of cell proliferation,PF07679;PF07714;,,,,,,,,,FGFR4_COTCO,Coturnix coturnix (Common quail) (Tetrao coturnix),positive regulation of cell proliferation [GO:0008284] comp115487_c1_seq1,376,41.2234,0.62980733,4,38,,4.00E-11,Q07409,Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein),Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein),GO:0031225; GO:0007155; GO:0005886,anchored to membrane; cell adhesion; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN3_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; nervous system development [GO:0007399] comp115496_c0_seq1,472,48.9407,0.72390897,17,18,,2.00E-10,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp115499_c0_seq1,869,41.0817,1.48174043,8,165,,4.00E-22,Q6ERS0,Putative CBL-interacting protein kinase 27 (EC 2.7.11.1) (OsCIPK27),Putative CBL-interacting protein kinase 27 (EC 2.7.11.1) (OsCIPK27),GO:0005524; GO:0004674; GO:0007165,ATP binding; protein serine/threonine kinase activity; signal transduction,PF03822;PF00069;,,,,,,,,,CIPKR_ORYSJ,Oryza sativa subsp. japonica (Rice),signal transduction [GO:0007165] comp115502_c1_seq1,611,38.9525,0.82165285,4,163,,9.00E-11,Q9BXJ4,Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),GO:0035356; GO:0005581; GO:0005615; GO:0045444; GO:0042593; GO:0042347; GO:0010629; GO:0045721; GO:0050728; GO:1900165; GO:0071638; GO:0070374; GO:0070165; GO:0050715; GO:0051897; GO:0070206,cellular triglyceride homeostasis; collagen; extracellular space; fat cell differentiation; glucose homeostasis; negative regulation of NF-kappaB import into nucleus; negative regulation of gene expression; negative regulation of gluconeogenesis; negative regulation of inflammatory response; negative regulation of interleukin-6 secretion; negative regulation of monocyte chemotactic protein-1 production; positive regulation of ERK1 and ERK2 cascade; positive regulation of adiponectin secretion; positive regulation of cytokine secretion; positive regulation of protein kinase B signaling cascade; protein trimerization,PF00386;PF01391;,,,,,,,,,C1QT3_HUMAN,Homo sapiens (Human),cellular triglyceride homeostasis [GO:0035356]; fat cell differentiation [GO:0045444]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; protein trimerization [GO:0070206] comp115514_c0_seq1,754,43.5013,0.67373236,8,86,,6.00E-58,Q9V576,Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen),Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen),GO:0045177; GO:0050829; GO:0009880; GO:0035234; GO:0035233; GO:0016021; GO:0045824; GO:0007424; GO:0008195; GO:0007280; GO:0042803; GO:0005918; GO:0019991,apical part of cell; defense response to Gram-negative bacterium; embryonic pattern specification; germ cell programmed cell death; germ cell repulsion; integral to membrane; negative regulation of innate immune response; open tracheal system development; phosphatidate phosphatase activity; pole cell migration; protein homodimerization activity; septate junction; septate junction assembly,PF01569;,,,,,,,,,WUN_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; dephosphorylation [GO:0016311]; ectopic germ cell programmed cell death [GO:0035234]; embryonic pattern specification [GO:0009880]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165] comp115518_c0_seq3,628,39.172,0.61979995,0,0,,,,,,,,,4.00E-13,CHOYP_contig_005213,,,,,,,,, comp115518_c0_seq4,595,38.4874,0.62803128,0,0,,,,,,,,,4.00E-12,CHOYP_contig_047502,,,,,,,,, comp115518_c0_seq5,870,39.0805,0.35896042,0,0,,,,,,,,,,,2.00E-48,ruditapes_c19765,,,,,,, comp115524_c0_seq3,395,46.8354,0.50947695,4,39,,4.00E-21,Q8IZC4,Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1),Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1),GO:0030097; GO:0005543; GO:0005886; GO:0008284; GO:0007165,hemopoiesis; phospholipid binding; plasma membrane; positive regulation of cell proliferation; signal transduction,PF08174;PF00169;,,,,,,,,,RTKN2_HUMAN,Homo sapiens (Human),hemopoiesis [GO:0030097]; signal transduction [GO:0007165] comp115542_c1_seq1,511,41.683,0.60509323,6,31,,1.00E-79,Q5RKZ7,Molybdenum cofactor biosynthesis protein 1 [Includes: Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A); Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C)],Molybdenum cofactor biosynthesis protein 1 [Includes: Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A); Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C)],GO:0051539; GO:0005525; GO:0006777; GO:0016829; GO:0046872; GO:0032324; GO:0019008,"4 iron, 4 sulfur cluster binding; GTP binding; Mo-molybdopterin cofactor biosynthetic process; lyase activity; metal ion binding; molybdopterin cofactor biosynthetic process; molybdopterin synthase complex",PF01967;PF06463;PF04055;,9.00E-58,CHOYP_BRAFLDRAFT_118735.1.1,,,,,,,MOCS1_MOUSE,Mus musculus (Mouse),molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp115542_c2_seq1,293,33.1058,0.14369669,8,40,,5.00E-06,Q7WB92,Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C),Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C),GO:0006777,Mo-molybdopterin cofactor biosynthetic process,PF01967;,,,,,,,,,MOAC_BORPA,Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp115553_c0_seq1,623,45.1043,0.41536205,26,13,,2.00E-48,Q9UIL4,Kinesin-like protein KIF25 (Kinesin-like protein 3),Kinesin-like protein KIF25 (Kinesin-like protein 3),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0000070; GO:0010507,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; mitotic sister chromatid segregation; negative regulation of autophagy,PF00225;,4.00E-57,CHOYP_BRAFLDRAFT_84054.2.2,,,,,,,KIF25_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of autophagy [GO:0010507]; organelle organization [GO:0006996] comp115553_c1_seq3,438,45.4338,0.53320116,0,0,,6.00E-17,O08672,Kinesin-like protein KIFC2,Kinesin-like protein KIFC2,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,,,,,,,,,KIFC2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp115554_c0_seq1,289,34.9481,0.46812506,10,6,,,,,,,,,,,4.00E-13,ruditapes_c4109,,,,,,, comp115555_c0_seq1,1606,44.2715,0.51105124,13,0,,4.00E-108,Q07113,Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),GO:0009986; GO:0030139; GO:0005768; GO:0001948; GO:0016021; GO:0005765; GO:0005537; GO:0016020; GO:0005641; GO:0051219; GO:0030140; GO:0005215,cell surface; endocytic vesicle; endosome; glycoprotein binding; integral to membrane; lysosomal membrane; mannose binding; membrane; nuclear envelope lumen; phosphoprotein binding; trans-Golgi network transport vesicle; transporter activity,PF00878;PF00040;,,,,,,,,,MPRI_MOUSE,Mus musculus (Mouse),liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; response to retinoic acid [GO:0032526]; spermatogenesis [GO:0007283] comp115555_c0_seq3,1296,44.3673,0.55258706,2,0,,2.00E-96,Q07113,Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),GO:0009986; GO:0030139; GO:0005768; GO:0001948; GO:0016021; GO:0005765; GO:0005537; GO:0016020; GO:0005641; GO:0051219; GO:0030140; GO:0005215,cell surface; endocytic vesicle; endosome; glycoprotein binding; integral to membrane; lysosomal membrane; mannose binding; membrane; nuclear envelope lumen; phosphoprotein binding; trans-Golgi network transport vesicle; transporter activity,PF00878;PF00040;,,,,,,,,,MPRI_MOUSE,Mus musculus (Mouse),liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; response to retinoic acid [GO:0032526]; spermatogenesis [GO:0007283] comp115579_c0_seq1,1422,38.6779,0.45536023,43,205,,4.00E-10,Q95LB0,Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),GO:0007597; GO:0009986; GO:0042627; GO:0031012; GO:0008201; GO:0034364; GO:0060230; GO:0016525; GO:0030195; GO:0010596; GO:0001937; GO:0051918; GO:0033033; GO:0034392; GO:0005543; GO:0031639; GO:0051006; GO:0006641; GO:0034361,"blood coagulation, intrinsic pathway; cell surface; chylomicron; extracellular matrix; heparin binding; high-density lipoprotein particle; lipoprotein lipase activator activity; negative regulation of angiogenesis; negative regulation of blood coagulation; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; negative regulation of fibrinolysis; negative regulation of myeloid cell apoptotic process; negative regulation of smooth muscle cell apoptotic process; phospholipid binding; plasminogen activation; positive regulation of lipoprotein lipase activity; triglyceride metabolic process; very-low-density lipoprotein particle",PF00084;PF09014;,,,,,,,,,APOH_PANTR,Pan troglodytes (Chimpanzee),"blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]" comp115605_c0_seq1,252,39.2857,1.14528552,4,0,,4.00E-07,Q9ULI3,Protein HEG homolog 1,Protein HEG homolog 1,GO:0005509; GO:0003209; GO:0005911; GO:0045216; GO:0001886; GO:0009897; GO:0005576; GO:0001701; GO:0016021; GO:0030324; GO:0003017; GO:0001945; GO:0035264; GO:0060039; GO:0009791; GO:0050878; GO:0001570; GO:0048845; GO:0003281,calcium ion binding; cardiac atrium morphogenesis; cell-cell junction; cell-cell junction organization; endothelial cell morphogenesis; external side of plasma membrane; extracellular region; in utero embryonic development; integral to membrane; lung development; lymph circulation; lymph vessel development; multicellular organism growth; pericardium development; post-embryonic development; regulation of body fluid levels; vasculogenesis; venous blood vessel morphogenesis; ventricular septum development,PF00008;PF07645;,,,,,,,,,HEG1_HUMAN,Homo sapiens (Human),cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp115605_c0_seq2,327,39.4495,0.72212026,9,21,,2.00E-27,Q04721,Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)],GO:0000139; GO:0007220; GO:0061314; GO:0006915; GO:0060413; GO:0046849; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0005789; GO:0005576; GO:0030097; GO:0005887; GO:0043066; GO:0008285; GO:0007399; GO:0005654; GO:0046579; GO:0003184; GO:0004872; GO:0006355; GO:0019827; GO:0006367,"Golgi membrane; Notch receptor processing; Notch signaling involved in heart development; apoptotic process; atrial septum morphogenesis; bone remodeling; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; endoplasmic reticulum membrane; extracellular region; hemopoiesis; integral to plasma membrane; negative regulation of apoptotic process; negative regulation of cell proliferation; nervous system development; nucleoplasm; positive regulation of Ras protein signal transduction; pulmonary valve morphogenesis; receptor activity; regulation of transcription, DNA-dependent; stem cell maintenance; transcription initiation from RNA polymerase II promoter",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; hemopoiesis [GO:0030097]; marginal zone B cell differentiation [GO:0002315]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; pulmonary valve morphogenesis [GO:0003184]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp115614_c0_seq1,241,56.0166,0.78499961,0,28,,5.00E-36,Q9H853,Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B),Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B),GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0005200,GTP binding; cytoplasm; microtubule; microtubule-based process; structural constituent of cytoskeleton,PF00091;,6.00E-37,CHOYP_LOC100373045.1.1,,,,,,,TBA4B_HUMAN,Homo sapiens (Human),microtubule-based process [GO:0007017] comp115614_c1_seq1,411,57.6642,1.0273643,0,71,,8.00E-97,Q9ZRJ4,Tubulin alpha chain,Tubulin alpha chain,GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,1.00E-106,CHOYP_LOC754102.1.1,6.00E-88,ruditapes2_lrc3145,,,,,TBA_CHLVU,Chlorella vulgaris (Green alga),microtubule-based process [GO:0007017] comp115614_c1_seq2,225,56.8889,0.99537077,0,5,,4.00E-06,Q08628,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization,,1.00E-13,CHOYP_TUBA4A.1.1,3.00E-31,ruditapes_lrc33808,,,,,TBA_BLEJA,Blepharisma japonicum,microtubule-based process [GO:0007017] comp115623_c0_seq1,1483,43.0209,0.46910089,50,150,,3.00E-111,Q8K2L8,Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15),Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15),GO:0005793; GO:0016192,endoplasmic reticulum-Golgi intermediate compartment; vesicle-mediated transport,,3.00E-95,CHOYP_LOC100659825.1.1,,,,,,,TPC12_MOUSE,Mus musculus (Mouse),vesicle-mediated transport [GO:0016192] comp115635_c0_seq1,547,42.596,0.24464367,2,0,,,,,,,,,1.00E-37,CHOYP_CF106.1.1,,,,,,,,, comp115635_c0_seq2,846,45.7447,0.29512236,34,24,,1.00E-64,Q5BL31,Uncharacterized protein C6orf106 homolog,Uncharacterized protein C6orf106 homolog,,,PF16158;,,,,,,,,,CF106_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),macroautophagy [GO:0016236] comp115639_c0_seq2,1074,39.2924,0.64268176,6,9,,,,,,,,,1.00E-15,CHOYP_BRM1L.1.1,,,,,,,,, comp115639_c0_seq3,1000,40.2,0.707662,0,0,,9.00E-82,Q4V8V1,Breast cancer metastasis-suppressor 1-like protein-A,Breast cancer metastasis-suppressor 1-like protein-A,GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08598;,,,,,,,,,BM1LA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp115640_c0_seq1,561,44.2068,0.44000923,11,21,,,,,,,,,1.00E-49,CHOYP_LOC583944.1.1,,,,,,,,, comp115640_c1_seq1,324,45.3704,0.30317453,10,18,,2.00E-24,Q0P5C0,Lipase maturation factor 1 (Transmembrane protein 112),Lipase maturation factor 1 (Transmembrane protein 112),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF06762;,4.00E-40,CHOYP_LOC100864539.1.1,,,,,,,LMF1_BOVIN,Bos taurus (Bovine),chylomicron remnant clearance [GO:0034382]; ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of lipoprotein lipase activity [GO:0051006]; protein glycosylation in Golgi [GO:0033578]; protein maturation [GO:0051604]; protein secretion [GO:0009306]; regulation of cholesterol metabolic process [GO:0090181]; regulation of triglyceride metabolic process [GO:0090207]; triglyceride metabolic process [GO:0006641] comp115640_c2_seq2,650,43.0769,0.49984762,24,14,,1.00E-51,Q9BU23,Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153),Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF06762;,,,,,,,,,LMF2_HUMAN,Homo sapiens (Human), comp115640_c3_seq1,202,45.0495,0.59013074,2,4,,5.00E-12,Q7ZWN0,Lipase maturation factor 2,Lipase maturation factor 2,GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF06762;,,,,,,,,,LMF2_XENLA,Xenopus laevis (African clawed frog), comp115649_c0_seq1,658,42.5532,0.23931369,24,27,,9.00E-54,Q96CN5,Leucine-rich repeat-containing protein 45,Leucine-rich repeat-containing protein 45,GO:0005813,centrosome,PF13516;,3.00E-39,CHOYP_LOC100376045.1.1,,,,,,,LRC45_HUMAN,Homo sapiens (Human), comp115654_c0_seq2,1046,44.4551,0.38011652,0,7,,7.00E-40,Q86UW6,NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein),NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein),GO:0005524; GO:0046404; GO:0005829; GO:0004519,ATP binding; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; cytosol; endonuclease activity,PF08590;PF01713;,1.00E-14,CHOYP_N4BP2.1.1,,,,,,,N4BP2_HUMAN,Homo sapiens (Human), comp115659_c0_seq1,720,32.7778,0.31808885,16,37,,2.00E-07,Q7LHG5,Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,,,,,,,,,YI31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp115665_c0_seq1,861,41.2311,0.3319219,55,9,,3.00E-16,Q5R7A4,Ras-related protein Rab-7L1 (Rab-7-like protein 1),Ras-related protein Rab-7L1 (Rab-7-like protein 1),GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,1.00E-34,CHOYP_LOC586472.1.1,,,,,,,RAB7L_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; negative regulation of neuron projection development [GO:0010977]; positive regulation of intracellular protein transport [GO:0090316]; protein transport [GO:0015031]; retrograde transport, plasma membrane to Golgi [GO:0035526]; small GTPase mediated signal transduction [GO:0007264]" comp115680_c1_seq1,235,46.383,0.31914033,5,0,,3.00E-08,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,,,,,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp115680_c2_seq1,434,42.1659,0.47271442,24,22,,3.00E-29,Q9P2R3,Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif),Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif),GO:0010008; GO:0005765; GO:0046872,endosome membrane; lysosomal membrane; metal ion binding,PF00023;PF12796;PF00651;PF01363;,,,,,,,,,ANFY1_HUMAN,Homo sapiens (Human),"endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" comp115682_c0_seq1,282,52.8369,1.3180121,3,43,,,,,,,,,3.00E-16,CHOYP_LOC100353582.2.2,,,,,,,,, comp115685_c1_seq1,639,44.9139,0.74853984,13,48,,5.00E-16,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp115685_c2_seq1,378,44.1799,0.92492752,3,28,,7.00E-07,Q9R0T4,Cadherin-1 (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3],Cadherin-1 (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3],GO:0005794; GO:0015629; GO:0016235; GO:0043296; GO:0005509; GO:0016342; GO:0005913; GO:0016337; GO:0071681; GO:0071285; GO:0005737; GO:0005768; GO:0005925; GO:0007156; GO:0016021; GO:0009898; GO:0016328; GO:0022408; GO:0031175; GO:0048471; GO:0021983; GO:0005886; GO:0042993; GO:0045893; GO:0072659; GO:0042493; GO:0010033; GO:0009636; GO:0007416; GO:0005802,"Golgi apparatus; actin cytoskeleton; aggresome; apical junction complex; calcium ion binding; catenin complex; cell-cell adherens junction; cell-cell adhesion; cellular response to indole-3-methanol; cellular response to lithium ion; cytoplasm; endosome; focal adhesion; homophilic cell adhesion; integral to membrane; internal side of plasma membrane; lateral plasma membrane; negative regulation of cell-cell adhesion; neuron projection development; perinuclear region of cytoplasm; pituitary gland development; plasma membrane; positive regulation of transcription factor import into nucleus; positive regulation of transcription, DNA-dependent; protein localization to plasma membrane; response to drug; response to organic substance; response to toxic substance; synapse assembly; trans-Golgi network",PF00028;PF01049;PF08758;,,,,,,,,,CADH1_RAT,Rattus norvegicus (Rat),"adherens junction organization [GO:0034332]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; establishment of protein localization to plasma membrane [GO:0090002]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription factor import into nucleus [GO:0042993]; response to drug [GO:0042493]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; single organismal cell-cell adhesion [GO:0016337]; synapse assembly [GO:0007416]" comp115685_c3_seq1,242,45.4545,0.64457334,0,8,,2.00E-08,Q8BIZ0,Protocadherin-20,Protocadherin-20,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;,,,,,,,,,PCD20_MOUSE,Mus musculus (Mouse),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp115690_c0_seq1,264,45.4545,0.51585835,3,0,,8.00E-11,Q924N4,Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),GO:0016323; GO:0071477; GO:0016021; GO:0006813; GO:0015379,basolateral plasma membrane; cellular hypotonic salinity response; integral to membrane; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,3.00E-15,CHOYP_S12A4.1.1,,,,,,,S12A6_MOUSE,Mus musculus (Mouse),cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826] comp115705_c0_seq1,626,39.4569,0.82283675,10,91,,3.00E-18,Q9Y394,Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4),Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,DHRS7_HUMAN,Homo sapiens (Human), comp115714_c0_seq1,415,38.7952,0.58046849,0,0,,7.00E-12,Q5RCD9,Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29),Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29),GO:0003677; GO:0030154; GO:0046872; GO:0007275; GO:0005634; GO:0003700; GO:0007283; GO:0006351,"DNA binding; cell differentiation; metal ion binding; multicellular organismal development; nucleus; sequence-specific DNA binding transcription factor activity; spermatogenesis; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSCA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp115714_c0_seq2,390,39.7436,0.45571395,0,0,,3.00E-13,Q9NYT6,Zinc finger protein 226,Zinc finger protein 226,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN226_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp115718_c0_seq1,210,44.2857,0.58721183,0,0,,1.00E-09,Q3T0Z5,Leukocyte receptor cluster member 1 homolog,Leukocyte receptor cluster member 1 homolog,,,PF10197;,,,,,,,,,LENG1_BOVIN,Bos taurus (Bovine), comp115726_c0_seq2,393,48.3461,0.39928195,1,33,,3.00E-18,P16086,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)",GO:0031532; GO:0051693; GO:0005509; GO:0005829; GO:0005886; GO:0043234; GO:0008091,actin cytoskeleton reorganization; actin filament capping; calcium ion binding; cytosol; plasma membrane; protein complex; spectrin,PF13499;PF08726;PF00018;PF00435;,,,,,,,,,SPTN1_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] comp115726_c1_seq1,241,46.888,0.67083622,2,18,,,,,,,,,8.00E-29,CHOYP_LOC100377364.2.2,,,,,,,,, comp115727_c0_seq1,635,45.5118,0.63984062,4,55,,2.00E-44,Q62688,Inactive phospholipase C-like protein 1 (PLC-L1) (PRIP1) (Phospholipase C-related but catalytically inactive protein) (p130),Inactive phospholipase C-like protein 1 (PLC-L1) (PRIP1) (Phospholipase C-related but catalytically inactive protein) (p130),GO:0005509; GO:0005737; GO:0035556; GO:0006629; GO:0004435; GO:0005543; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid metabolic process; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF09279;PF16457;PF00388;PF00387;,1.00E-56,CHOYP_PLCL2.1.1,,,,,,,PLCL1_RAT,Rattus norvegicus (Rat),"intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; regulation of synaptic transmission, GABAergic [GO:0032228]" comp115728_c0_seq1,1222,44.2717,0.62916959,93,548,,4.00E-168,Q6NZ22,Methyltransferase-like protein 14 (EC 2.1.1.-),N6-adenosine-methyltransferase subunit METTL14 (EC 2.1.1.62) (Methyltransferase-like protein 14),GO:0016422; GO:0005634,mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity; nucleus,PF05063;,5.00E-141,CHOYP_MET14.1.1,,,,,,,MET14_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA splicing, via spliceosome [GO:0000398]; RNA methylation [GO:0001510]; stem cell population maintenance [GO:0019827]" comp115737_c1_seq1,269,59.8513,1.08838713,3,2,,4.00E-07,P36922,Putative Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase EbsC (EC 4.2.-.-) (Protein EbsC),Putative Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase EbsC (EC 4.2.-.-) (Protein EbsC),GO:0002161; GO:0016829; GO:0006355; GO:0006450; GO:0006351; GO:0006412,"aminoacyl-tRNA editing activity; lyase activity; regulation of transcription, DNA-dependent; regulation of translational fidelity; transcription, DNA-dependent; translation",PF04073;,,,,,,,,,EBSC_ENTFA,Enterococcus faecalis (strain ATCC 700802 / V583),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]" comp115740_c0_seq1,1154,36.0485,0.79296935,1054,122,,4.00E-107,Q29503,Ubiquitin-conjugating enzyme E2 R2 (EC 6.3.2.19) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2),Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2),GO:0005524; GO:0070936; GO:0006513; GO:0004842,ATP binding; protein K48-linked ubiquitination; protein monoubiquitination; ubiquitin-protein ligase activity,PF00179;,2.00E-120,CHOYP_MYSP.6.9,,,,,,,UB2R2_RABIT,Oryctolagus cuniculus (Rabbit),protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513] comp115756_c0_seq1,559,44.0072,0.33322421,20,70,,1.00E-41,Q0V9L1,MMS19 nucleotide excision repair protein homolog (MMS19-like protein),MMS19 nucleotide excision repair protein homolog (MMS19-like protein),GO:0097361; GO:0006281; GO:0016226; GO:0005634; GO:0005819,CIA complex; DNA repair; iron-sulfur cluster assembly; nucleus; spindle,PF12460;,,,,,,,,,MMS19_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226] comp115758_c0_seq1,931,41.5682,0.82820001,30,192,,2.00E-11,O93295,Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase),Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase),GO:0005524; GO:0016787; GO:0016021; GO:0046872; GO:0005886,ATP binding; hydrolase activity; integral to membrane; metal ion binding; plasma membrane,PF01150;,,,,,,,,,ENTP8_CHICK,Gallus gallus (Chicken), comp115792_c1_seq1,354,49.7175,0.24763032,4,0,,,,,,,,,1.00E-15,CHOYP_MATN1.3.5,,,,,,,,, comp115807_c0_seq1,686,43.0029,0.46463867,0,0,,4.00E-19,Q8C5H1,Anoctamin-4 (Transmembrane protein 16D),Anoctamin-4 (Transmembrane protein 16D),GO:0016021; GO:0005622; GO:0005886,integral to membrane; intracellular; plasma membrane,PF16178;PF04547;,,,,,,,,,ANO4_MOUSE,Mus musculus (Mouse),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821] comp115807_c0_seq2,920,43.913,0.42652103,4,7,,9.00E-20,Q32M45,Anoctamin-4 (Transmembrane protein 16D),Anoctamin-4 (Transmembrane protein 16D),GO:0016021; GO:0005622; GO:0034220; GO:0005886,integral to membrane; intracellular; ion transmembrane transport; plasma membrane,PF16178;PF04547;,,,,,,,,,ANO4_HUMAN,Homo sapiens (Human),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220] comp115807_c0_seq3,842,43.7055,0.39507039,9,3,,3.00E-07,Q14AT5,Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G),Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G),GO:0005254; GO:0005783; GO:0016021; GO:0005634; GO:0005886,chloride channel activity; endoplasmic reticulum; integral to membrane; nucleus; plasma membrane,PF16178;PF04547;,,,,,,,,,ANO7_MOUSE,Mus musculus (Mouse),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821] comp115808_c0_seq1,1176,43.5374,0.43395069,33,59,,2.00E-89,Q8BK03,Protein FAM73B,Mitoguardin-2 (Protein FAM73B),GO:0060348; GO:0016021,bone development; integral to membrane,PF10265;,3.00E-113,CHOYP_AAEL_AAEL006016.1.1,,,,,,,FA73B_MOUSE,Mus musculus (Mouse),bone development [GO:0060348]; mitochondrial fusion [GO:0008053] comp115820_c0_seq2,960,42.9167,0.4777704,23,4,,8.00E-72,Q6P4S8,Integrator complex subunit 1 (Int1),Integrator complex subunit 1 (Int1),GO:0034474; GO:0001833; GO:0016021; GO:0032039; GO:0043066; GO:0043154; GO:0031965; GO:0005634,U2 snRNA 3'-end processing; inner cell mass cell proliferation; integral to membrane; integrator complex; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nuclear membrane; nucleus,PF12432;,,,,,,,,,INT1_MOUSE,Mus musculus (Mouse),blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] comp115841_c0_seq1,498,31.3253,0.65625778,18,15,,,,,,,,,8.00E-14,CHOYP_contig_036501,,,,,,,,, comp115843_c0_seq1,1804,39.6341,0.29721495,784,3635,,4.00E-128,Q9Y236,Oxidative stress-induced growth inhibitor 2 (hT41),Oxidative stress-induced growth inhibitor 2 (hT41),GO:0007281; GO:0007126,germ cell development; meiosis,,2.00E-33,CHOYP_OSGI2.1.1,,,,,,,OSGI2_HUMAN,Homo sapiens (Human),meiotic cell cycle [GO:0051321] comp115847_c1_seq1,280,42.1429,0.48658629,3,13,,3.00E-20,Q95KG9,Vacuolar fusion protein MON1 homolog A,Vacuolar fusion protein MON1 homolog A,,,PF03164;,,,,,,,,,MON1A_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp115848_c0_seq1,619,43.1341,0.6643374,0,62,,5.00E-20,P63047,Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),GO:0005737; GO:0008202; GO:0008146; GO:0006790,cytoplasm; steroid metabolic process; sulfotransferase activity; sulfur compound metabolic process,PF00685;,,,,,,,,,ST4A1_RAT,Rattus norvegicus (Rat),steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790] comp115857_c0_seq1,460,45.2174,0.21313092,17,0,,5.00E-23,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp115859_c0_seq2,1096,40.3285,0.25081082,47,262,,1.00E-68,Q9CXE6,DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3),DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3),GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0008094; GO:0005759; GO:0005634; GO:0048471,ATP binding; DNA binding; DNA recombination; DNA repair; DNA-dependent ATPase activity; mitochondrial matrix; nucleus; perinuclear region of cytoplasm,PF08423;,,,,,,,,,XRCC3_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; meiotic DNA recombinase assembly [GO:0000707]; mitotic recombination [GO:0006312]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; reciprocal meiotic recombination [GO:0007131]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; response to ionizing radiation [GO:0010212]; response to organic substance [GO:0010033]; strand invasion [GO:0042148]; t-circle formation [GO:0090656]; telomere maintenance via recombination [GO:0000722] comp115863_c0_seq1,288,43.0556,0.15844489,3,36,,1.00E-10,P61583,HERV-K_3q12.3 provirus Np9 protein (Endogenous retrovirus K protein 5) (HERV-K(II) Np9 protein),Endogenous retrovirus group K member 5 Np9 protein (Endogenous retrovirus K protein 5) (HERV-K(II) Np9 protein) (HERV-K_3q12.3 provirus Np9 protein),GO:0005634,nucleus,,,,,,,,,,NP8_HUMAN,Homo sapiens (Human), comp115873_c0_seq1,698,42.6934,0.57713067,8,93,,,,,,,,,2.00E-11,CHOYP_PHT4.1.1,,,,,,,,, comp115888_c0_seq1,1855,36.9811,0.4740621,1446,3312,,4.00E-21,Q9D0G0,"28S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt)","28S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF07147;,,,,,,,,,RT30_MOUSE,Mus musculus (Mouse),translation [GO:0006412] comp115908_c0_seq2,695,48.9209,0.77519217,5,11,,5.00E-78,Q9UA35,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),GO:0016021; GO:0005415,integral to membrane; nucleoside:sodium symporter activity,PF07670;PF07662;PF01773;,3.00E-52,CHOYP_S28A2.1.1,,,,,,,S28A3_EPTST,Eptatretus stoutii (Pacific hagfish), comp115908_c0_seq3,649,49.6148,0.75722454,4,4,,,,,,,,,3.00E-15,CHOYP_NEMVEDRAFT_V1G135437.1.2,,,,,,,,, comp115914_c0_seq2,697,41.4634,0.58045858,35,43,,7.00E-40,A2A4P0,ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8),ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0071013; GO:0006397,ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; catalytic step 2 spliceosome; mRNA processing,PF04408;PF00271;PF07717;PF00575;,2.00E-35,CHOYP_DHX8.2.3,,,,,,,DHX8_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp115918_c0_seq1,310,40.9677,0.54398367,1,20,,2.00E-19,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp115919_c0_seq1,1448,37.9144,0.37089795,2637,3,male>female,4.00E-76,Q5XHC1,UPF0602 protein C4orf47 homolog,UPF0602 protein C4orf47 homolog,,,PF15239;,3.00E-113,CHOYP_LOC591073.1.1,,,,,,,CD047_XENLA,Xenopus laevis (African clawed frog), comp115921_c0_seq1,772,39.7668,0.13495134,12,104,,9.00E-76,Q5R7A2,"Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase)","Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase)",GO:0004578; GO:0005789; GO:0016021; GO:0006486,chitobiosyldiphosphodolichol beta-mannosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; protein glycosylation,PF00534;,9.00E-16,CHOYP_ALG1.1.1,,,,,,,ALG1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein glycosylation [GO:0006486] comp115942_c0_seq1,862,43.7355,0.51163188,47,29,,1.00E-101,Q28BM0,Dymeclin,Dymeclin,GO:0005794,Golgi apparatus,,8.00E-80,CHOYP_LOC100374358.1.1,,,,,,,DYM_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),Golgi organization [GO:0007030] comp115947_c0_seq1,1387,42.8262,0.62335362,1168,2275,,0,Q90593,78 kDa glucose-regulated protein (GRP-78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP),78 kDa glucose-regulated protein (GRP-78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP),GO:0005524; GO:0008180; GO:0006983; GO:0006987; GO:0009986; GO:0042149; GO:0071353; GO:0021680; GO:0021589; GO:0034663; GO:0005788; GO:0005793; GO:0030176; GO:0030496; GO:0043066; GO:0030512; GO:0031398; GO:0051603; GO:0043022,ATP binding; COP9 signalosome; ER overload response; activation of signaling protein activity involved in unfolded protein response; cell surface; cellular response to glucose starvation; cellular response to interleukin-4; cerebellar Purkinje cell layer development; cerebellum structural organization; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; integral to endoplasmic reticulum membrane; midbody; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of protein ubiquitination; proteolysis involved in cellular protein catabolic process; ribosome binding,PF00012;,0,CHOYP_GRP78.2.5,,,,,,,GRP78_CHICK,Gallus gallus (Chicken),activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; ER overload response [GO:0006983]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; proteolysis involved in cellular protein catabolic process [GO:0051603]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998] comp115953_c0_seq1,520,40.7692,0.41971154,25,26,,6.00E-47,O00409,Forkhead box protein N3 (Checkpoint suppressor 1),Forkhead box protein N3 (Checkpoint suppressor 1),GO:0000077; GO:0000085; GO:0045892; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"DNA damage checkpoint; mitotic G2 phase; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,7.00E-34,CHOYP_FOXN2_3.1.1,,,,,,,FOXN3_HUMAN,Homo sapiens (Human),"mitotic G2 DNA damage checkpoint [GO:0007095]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp115959_c0_seq1,330,42.7273,0.86930091,0,38,,1.00E-07,P08125,Collagen alpha-1(X) chain,Collagen alpha-1(X) chain,GO:0005581; GO:0005576,collagen; extracellular region,PF00386;PF01391;,,,,,,,,,COAA1_CHICK,Gallus gallus (Chicken), comp115959_c1_seq1,477,49.4759,0.6579758,0,86,,1.00E-07,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp115961_c0_seq1,700,45.4286,0.36569095,4,16,,5.00E-40,Q5SSH7,Zinc finger ZZ-type and EF-hand domain-containing protein 1,Zinc finger ZZ-type and EF-hand domain-containing protein 1,GO:0005509; GO:0008270,calcium ion binding; zinc ion binding,PF03256;PF00569;,3.00E-47,CHOYP_BRAFLDRAFT_88583.1.1,,,,,,,ZZEF1_MOUSE,Mus musculus (Mouse), comp115961_c0_seq3,638,44.6708,0.38340094,3,0,,,,,,,,,2.00E-42,CHOYP_BRAFLDRAFT_88583.1.1,,,,,,,,, comp115973_c0_seq1,415,43.6145,0.32298324,13,15,,6.00E-15,Q15075,Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2),Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2),GO:0005545; GO:0030742; GO:0005516; GO:0005829; GO:0005769; GO:0031901; GO:0045022; GO:0019897; GO:0042803; GO:0055037; GO:0005969; GO:0016189; GO:0006906; GO:0008270,1-phosphatidylinositol binding; GTP-dependent protein binding; calmodulin binding; cytosol; early endosome; early endosome membrane; early endosome to late endosome transport; extrinsic to plasma membrane; protein homodimerization activity; recycling endosome; serine-pyruvate aminotransferase complex; synaptic vesicle to endosome fusion; vesicle fusion; zinc ion binding,PF01363;,,,,,,,,,EEA1_HUMAN,Homo sapiens (Human),early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] comp115975_c1_seq1,575,47.8261,0.3427469,21,15,,2.00E-87,P42346,Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),GO:0005524; GO:0000082; GO:0000139; GO:0016605; GO:0001030; GO:0001031; GO:0001032; GO:0031929; GO:0031931; GO:0031932; GO:0030030; GO:0071456; GO:0031669; GO:0005829; GO:0008144; GO:0005789; GO:0007281; GO:0005764; GO:0070438; GO:0005741; GO:0051534; GO:0010507; GO:0045792; GO:0016242; GO:0005634; GO:0018105; GO:0018107; GO:0030838; GO:0001938; GO:0010592; GO:0046889; GO:0010831; GO:0050731; GO:0051897; GO:0051496; GO:0045945; GO:0045727; GO:0046777; GO:0004674; GO:0032314; GO:0043610; GO:0031998; GO:0005979; GO:0045859; GO:0032095; GO:0043200; GO:0032868; GO:0043022; GO:0031529,ATP binding; G1/S transition of mitotic cell cycle; Golgi membrane; PML body; RNA polymerase III type 1 promoter DNA binding; RNA polymerase III type 2 promoter DNA binding; RNA polymerase III type 3 promoter DNA binding; TOR signaling cascade; TORC1 complex; TORC2 complex; cell projection organization; cellular response to hypoxia; cellular response to nutrient levels; cytosol; drug binding; endoplasmic reticulum membrane; germ cell development; lysosome; mTOR-FKBP12-rapamycin complex; mitochondrial outer membrane; negative regulation of NFAT protein import into nucleus; negative regulation of autophagy; negative regulation of cell size; negative regulation of macroautophagy; nucleus; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; positive regulation of lamellipodium assembly; positive regulation of lipid biosynthetic process; positive regulation of myotube differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase III promoter; positive regulation of translation; protein autophosphorylation; protein serine/threonine kinase activity; regulation of Rac GTPase activity; regulation of carbohydrate utilization; regulation of fatty acid beta-oxidation; regulation of glycogen biosynthetic process; regulation of protein kinase activity; regulation of response to food; response to amino acid stimulus; response to insulin stimulus; ribosome binding; ruffle organization,PF11865;PF02259;PF02260;PF00454;PF08771;,2.00E-92,CHOYP_MTOR.2.2,,,,,,,MTOR_RAT,Rattus norvegicus (Rat),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] comp115977_c0_seq1,1143,35.8705,0.56381108,2438,913,,1.00E-108,Q5PPV3,MORN repeat-containing protein 3,MORN repeat-containing protein 3,,,PF02493;,6.00E-134,CHOYP_BRAFLDRAFT_280249.1.1,,,9.00E-97,AM866946.p.cg.6,5,male gonad,MORN3_XENLA,Xenopus laevis (African clawed frog), comp115981_c0_seq1,820,41.3415,0.54949356,0,0,,7.00E-10,O34481,Uncharacterized protein YrrC,ATP-dependent RecD-like DNA helicase (EC 3.6.4.12),GO:0005524; GO:0017111,ATP binding; nucleoside-triphosphatase activity,PF14490;PF13538;,,,,,,,,,YRRC_BACSU,Bacillus subtilis (strain 168), comp115981_c0_seq2,934,41.2206,0.46046564,5,5,,2.00E-60,Q6NVF4,DNA helicase B (EC 3.6.4.12),DNA helicase B (EC 3.6.4.12),GO:0005524; GO:0043141; GO:0004003; GO:0006269; GO:0005658; GO:0017116,"ATP binding; ATP-dependent 5'-3' DNA helicase activity; ATP-dependent DNA helicase activity; DNA replication, synthesis of RNA primer; alpha DNA polymerase:primase complex; single-stranded DNA-dependent ATP-dependent DNA helicase activity",PF13538;,,,,,,,,,HELB_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA double-strand break processing [GO:1903775]" comp115997_c0_seq1,1707,38.6643,1.08415551,1057,5025,,5.00E-18,P15870,Histone H1-delta,Histone H1-delta,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00538;,,,1.00E-21,ruditapes_c7529,,,,,H1D_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),nucleosome assembly [GO:0006334] comp115999_c0_seq1,717,46.0251,0.40647724,30,2,,5.00E-31,O34309,"Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)","Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)",GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,,,,,,,,,PPS_BACSU,Bacillus subtilis (strain 168), comp115999_c0_seq2,365,44.1096,0.46923429,1,0,,7.00E-18,Q0VZ70,Chondramide synthase cmdD [Includes: ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent tyrosine adenylase (TrpA) (Tyrosine activase)],Chondramide synthase cmdD [Includes: ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent tyrosine adenylase (TrpA) (Tyrosine activase)],GO:0043042; GO:0016788; GO:0016874; GO:0016310; GO:0009403; GO:0016772,"amino acid adenylylation by nonribosomal peptide synthase; hydrolase activity, acting on ester bonds; ligase activity; phosphorylation; toxin biosynthetic process; transferase activity, transferring phosphorus-containing groups",PF00501;PF13193;PF00668;PF08241;PF00391;PF00550;PF00975;,1.00E-15,CHOYP_LOC100890479.1.3,,,,,,,CHSAD_CHOCO,Chondromyces crocatus,amino acid adenylylation by nonribosomal peptide synthase [GO:0043042]; phosphorylation [GO:0016310]; toxin biosynthetic process [GO:0009403] comp116002_c0_seq1,1315,48.0608,0.83190897,73,39,,,,,,,,,1.00E-23,CHOYP_BRAFLDRAFT_102618.1.1,,,,,,,,, comp116006_c0_seq1,1152,36.8056,0.4125319,7,43,,2.00E-15,A4QN56,Sodium-dependent glucose transporter 1,Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B),GO:0016324; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,NAGT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp116007_c0_seq1,1744,32.3394,0.68037201,895,4215,,1.00E-18,Q8IYN6,UBA-like domain-containing protein 2,UBA-like domain-containing protein 2,,,,5.00E-61,CHOYP_UBD2A.1.1,,,,,,,F100B_HUMAN,Homo sapiens (Human), comp116014_c0_seq1,399,45.8647,0.47790025,18,5,,5.00E-67,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,1.00E-86,CHOYP_LOC100123553.1.1,,,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116021_c0_seq2,255,48.2353,0.48095211,7,0,,3.00E-11,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp116022_c0_seq1,523,45.1243,0.52994487,0,0,,2.00E-73,Q3SZP5,Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),GO:0003995; GO:0003997; GO:0033540; GO:0019395; GO:0050660; GO:0006091; GO:0005777; GO:0006693,acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid oxidation; flavin adenine dinucleotide binding; generation of precursor metabolites and energy; peroxisome; prostaglandin metabolic process,PF01756;PF02770;PF14749;,,,,,,,,,ACOX1_BOVIN,Bos taurus (Bovine),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693] comp116027_c1_seq1,593,45.0253,0.20530012,40,0,,4.00E-12,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp116032_c0_seq1,1030,39.9029,0.70951657,4,112,,3.00E-36,Q66IB8,UPF0538 protein C2orf76 homolog,UPF0538 protein C2orf76 homolog,,,PF10209;,,,,,,,,,CB076_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp116032_c0_seq3,1011,40.1583,0.71302305,74,496,,,,,,,,,8.00E-24,CHOYP_NFX1.1.2,,,,,,,,, comp116032_c0_seq4,955,40.8377,0.7303293,6,86,,4.00E-36,Q66IB8,UPF0538 protein C2orf76 homolog,UPF0538 protein C2orf76 homolog,,,PF10209;,2.00E-18,CHOYP_CB076.1.1,,,,,,,CB076_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp116035_c0_seq1,804,30.7214,0.85798161,791,1294,,8.00E-17,B7Q290,Uncharacterized protein ISCW010018,Uncharacterized protein NCBP2-AS2 homolog,,,,,,,,,,,,YC029_IXOSC,Ixodes scapularis (Black-legged tick) (Deer tick), comp116041_c0_seq3,659,44.0061,0.64402959,0,0,,5.00E-24,O88801,Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2),Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2),GO:0030054; GO:0005737; GO:0030425; GO:0043025; GO:0014069; GO:0045211; GO:0019904; GO:0042803,cell junction; cytoplasm; dendrite; neuronal cell body; postsynaptic density; postsynaptic membrane; protein domain specific binding; protein homodimerization activity,PF00568;,,,,,,,,,HOME2_RAT,Rattus norvegicus (Rat),sensory perception of sound [GO:0007605] comp116042_c0_seq2,1071,41.6433,0.8408696,7,50,,2.00E-09,Q8BUJ9,Low-density lipoprotein receptor-related protein 12 (LRP-12),Low-density lipoprotein receptor-related protein 12 (LRP-12),GO:0005905; GO:0006897; GO:0005887,coated pit; endocytosis; integral to plasma membrane,PF00431;PF00057;,,,,,,,,,LRP12_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897] comp116048_c0_seq1,329,45.2888,0.36039649,26,0,,3.00E-12,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,3.00E-11,CHOYP_LOC100699850.1.3,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp116052_c0_seq1,432,50,0.94632905,23,481,,,,,,,,,4.00E-61,CHOYP_RN45S.4.5,,,,,,,,, comp116063_c1_seq1,514,44.9416,0.96558038,13,38,,2.00E-16,Q8CJ78,Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs),Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN628_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116074_c1_seq1,358,46.3687,0.63560773,0,10,,9.00E-06,Q9W5U2,Probable chitinase 3 (EC 3.2.1.14) (Probable chitinase 1),Probable chitinase 3 (EC 3.2.1.14) (Probable chitinase 1),GO:0008061; GO:0006032; GO:0004568; GO:0005576; GO:0000272,chitin binding; chitin catabolic process; chitinase activity; extracellular region; polysaccharide catabolic process,PF01607;PF00704;,,,,,,,,,CHIT3_DROME,Drosophila melanogaster (Fruit fly),chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] comp116078_c0_seq1,558,37.9928,0.66184183,22,15,,4.00E-46,Q5R6Q2,Syntaxin-6,Syntaxin-6,GO:0000139; GO:0048193; GO:0016021; GO:0006886,Golgi membrane; Golgi vesicle transport; integral to membrane; intracellular protein transport,PF05739;PF09177;,1.00E-50,CHOYP_LOC100367266.1.1,,,,,,,STX6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025] comp116081_c0_seq1,475,45.0526,0.62631857,1,43,,4.00E-32,P59267,Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 2) (DHHC-2),Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 2) (DHHC-2),GO:0005887; GO:0016409; GO:0018345; GO:0055038; GO:0008270,integral to plasma membrane; palmitoyltransferase activity; protein palmitoylation; recycling endosome membrane; zinc ion binding,PF01529;,2.00E-60,CHOYP_BRAFLDRAFT_117158.2.2,,,,,,,ZDHC2_MOUSE,Mus musculus (Mouse),protein palmitoylation [GO:0018345] comp116081_c0_seq2,436,41.7431,0.63333667,2,0,,2.00E-29,Q5FWL7,Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15 homolog) (DHHC-15),Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15 homolog) (DHHC-15),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,3.00E-44,CHOYP_BRAFLDRAFT_117158.1.2,,,,,,,ZDH15_XENLA,Xenopus laevis (African clawed frog), comp116084_c0_seq1,1716,35.4312,0.7439096,1299,4168,,2.00E-58,Q7ZXB8,Polyadenylate-binding protein 2-B (PABP-2-B) (Poly(A)-binding protein 2-B) (Nuclear poly(A)-binding protein 1-B) (Poly(A)-binding protein II-B) (PABII-B) (Polyadenylate-binding nuclear protein 1-B) (XLnPABP2-B) (nPABP2-B) (xPABPII-B),Polyadenylate-binding protein 2-B (PABP-2-B) (Poly(A)-binding protein 2-B) (Nuclear poly(A)-binding protein 1-B) (Poly(A)-binding protein II-B) (PABII-B) (Polyadenylate-binding nuclear protein 1-B) (XLnPABP2-B) (nPABP2-B) (xPABPII-B),GO:0005737; GO:0006378; GO:0000166; GO:0005634; GO:0008143,cytoplasm; mRNA polyadenylation; nucleotide binding; nucleus; poly(A) RNA binding,PF00076;,2.00E-84,CHOYP_PABP2.1.1,,,6.00E-82,AM860925.p.cg.6,9,,PAB2B_XENLA,Xenopus laevis (African clawed frog),mRNA polyadenylation [GO:0006378] comp116085_c0_seq1,639,36.6197,0.47432118,11,63,,2.00E-07,Q13360,Zinc finger protein 177,Zinc finger protein 177,GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN177_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp116088_c0_seq1,263,65.019,1.14016694,0,5,,6.00E-38,A4WQY8,Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE),Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE),GO:0017004; GO:0016021; GO:0046872; GO:0005886; GO:0017003,cytochrome complex assembly; integral to membrane; metal ion binding; plasma membrane; protein-heme linkage,PF03100;,,,,,,,,,CCME_RHOS5,Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3),cytochrome complex assembly [GO:0017004]; protein-heme linkage [GO:0017003] comp11608_c0_seq1,249,50.6024,0.51217215,1,3,,6.00E-10,Q9QZZ4,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,2.00E-24,CHOYP_MYO15.1.1,,,,,,,MYO15_MOUSE,Mus musculus (Mouse),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp116097_c1_seq1,242,35.124,0.40636145,4,2,,,,,,,,,,,3.00E-25,ruditapes_c20030,,,,,,, comp116098_c0_seq4,366,44.8087,0.83371817,11,0,,2.00E-10,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,6.00E-14,CHOYP_LOC100892567.6.8,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp116102_c0_seq1,1272,39.544,0.66859285,325,970,,1.00E-26,Q9Y580,RNA-binding protein 7 (RNA-binding motif protein 7),RNA-binding protein 7 (RNA-binding motif protein 7),GO:0003723; GO:0007126; GO:0000166,RNA binding; meiosis; nucleotide binding,PF00076;,,,,,,,,,RBM7_HUMAN,Homo sapiens (Human),meiotic cell cycle [GO:0051321] comp116110_c0_seq2,591,45.6853,0.81278721,19,30,,7.00E-07,Q61097,Kinase suppressor of Ras 1 (mKSR1) (Protein Hb),Kinase suppressor of Ras 1 (mKSR1) (Protein Hb),GO:0005524; GO:0005078; GO:0005789; GO:0035556; GO:0046872; GO:0043410; GO:0004674,ATP binding; MAP-kinase scaffold activity; endoplasmic reticulum membrane; intracellular signal transduction; metal ion binding; positive regulation of MAPK cascade; protein serine/threonine kinase activity,PF13543;PF07714;,,,,,,,,,KSR1_MOUSE,Mus musculus (Mouse),cAMP-mediated signaling [GO:0019933]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265] comp116117_c0_seq1,807,42.5031,0.49969155,36,78,,5.00E-36,Q04462,Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),GO:0005524; GO:0002161; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00043;PF00133;,,,,,,,,,SYVC_RAT,Rattus norvegicus (Rat),valyl-tRNA aminoacylation [GO:0006438] comp116124_c0_seq1,207,49.7585,0.47166634,1,23,,2.00E-07,Q5H9K5,Zinc finger matrin-type protein 1,Zinc finger matrin-type protein 1,GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,,,,,,,,,,ZMAT1_HUMAN,Homo sapiens (Human),intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332] comp116124_c0_seq2,228,54.386,0.53672907,1,27,,7.00E-15,Q8WTZ3,Zinc finger protein ENSP00000375192,Zinc finger protein ENSP00000375192,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,YS049_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116134_c0_seq1,694,46.83,0.26665187,34,31,,2.00E-45,O43184,Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha),Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha),GO:0007155; GO:0007173; GO:0005576; GO:0016021; GO:0004222; GO:0008237; GO:0005739; GO:0007520; GO:0005634; GO:0005886; GO:0006508; GO:0008270,cell adhesion; epidermal growth factor receptor signaling pathway; extracellular region; integral to membrane; metalloendopeptidase activity; metallopeptidase activity; mitochondrion; myoblast fusion; nucleus; plasma membrane; proteolysis; zinc ion binding,PF08516;PF00200;PF01562;PF01421;,3.00E-34,CHOYP_LOC100883390.1.1,,,,,,,ADA12_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; myoblast fusion [GO:0007520] comp116134_c0_seq2,332,43.9759,0,15,3,,7.00E-15,Q0NZX7,Zinc metalloproteinase-disintegrin-like bothrojarin-4 (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP) (Fragment),Zinc metalloproteinase-disintegrin-like bothrojarin-4 (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP) (Fragment),GO:0005576; GO:0046872; GO:0008237; GO:0006508,extracellular region; metal ion binding; metallopeptidase activity; proteolysis,PF00200;,,,,,,,,,VM3B4_BOTJA,Bothrops jararaca (Jararaca) (Bothrops jajaraca), comp116134_c1_seq1,845,38.1065,0.5222834,27,83,,5.00E-28,D6PXE8,Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP),Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP),GO:0005576; GO:0004222; GO:0006508; GO:0008270,extracellular region; metalloendopeptidase activity; proteolysis; zinc ion binding,PF08516;PF01562;PF01421;,,,,,,,,,VM3B_NAJAT,Naja atra (Chinese cobra), comp116134_c3_seq1,378,47.0899,0.24829838,8,39,,4.00E-10,Q9W7S2,Snake venom metalloproteinase aculysin-1 (SVMP) (EC 3.4.24.-),Snake venom metalloproteinase aculysin-1 (SVMP) (EC 3.4.24.-),GO:0005509; GO:0005576; GO:0004222; GO:0006508; GO:0008270,calcium ion binding; extracellular region; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01562;PF01421;,,,,,,,,,VM1A1_DEIAC,Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus), comp116140_c0_seq3,485,38.3505,0.74505034,1,0,,4.00E-08,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp116147_c0_seq1,349,37.2493,0.49893496,2,11,,1.00E-08,Q28G71,Forkhead box protein N3,Forkhead box protein N3,GO:0007049; GO:0045892; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"cell cycle; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,3.00E-24,CHOYP_FOXN1.1.1,,,,,,,FOXN3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell cycle [GO:0007049]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp116147_c2_seq1,605,47.1074,0.44857999,4,89,,1.00E-22,Q3BJS1,Forkhead box protein N4,Forkhead box protein N4,GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXN4_XENLA,Xenopus laevis (African clawed frog),"amacrine cell differentiation [GO:0035881]; atrioventricular canal development [GO:0036302]; heart looping [GO:0001947]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of heart contraction [GO:0008016]; regulation of transcription, DNA-templated [GO:0006355]; retina layer formation [GO:0010842]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron fate commitment [GO:0060579]" comp116156_c0_seq1,422,44.0758,0.78698116,17,0,,2.00E-14,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp116156_c1_seq1,498,43.7751,0.96632536,45,0,,7.00E-16,Q91641,Thyroid hormone-induced protein B,Thyroid hormone-induced protein B,GO:0005615; GO:0016020; GO:0007275,extracellular space; membrane; multicellular organismal development,PF00629;,,,,,,,,,THIB_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275] comp116163_c1_seq1,972,34.2593,0.67613999,23,197,,3.00E-22,A1YF12,Zinc finger protein 16,Zinc finger protein 16,GO:0003677; GO:0007049; GO:0051301; GO:0072707; GO:0046872; GO:0043066; GO:0005634; GO:1901989; GO:0051781; GO:0008284; GO:0045648; GO:0033674; GO:0045654; GO:0006355; GO:0006351,"DNA binding; cell cycle; cell division; cellular response to sodium dodecyl sulfate; metal ion binding; negative regulation of apoptotic process; nucleus; positive regulation of cell cycle phase transition; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of erythrocyte differentiation; positive regulation of kinase activity; positive regulation of megakaryocyte differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZNF16_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),"cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116165_c0_seq1,523,41.8738,0.35021014,22,12,,5.00E-43,Q28H30,UPF0489 protein C5orf22 homolog,UPF0489 protein C5orf22 homolog,,,PF12640;,,,,,,,,,CE022_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp116174_c0_seq1,761,42.9698,0.7698135,20,72,,2.00E-07,Q5U3U0,Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-),Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-),GO:0051213; GO:0046872,dioxygenase activity; metal ion binding,PF05721;,,,,,,,,,PHYD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp116175_c0_seq1,599,44.9082,0.60402853,23,63,,3.00E-76,Q8K1Y2,Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu),Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu),GO:0005524; GO:0005737; GO:0035556; GO:0016020; GO:0046872; GO:0005543; GO:0004697,ATP binding; cytoplasm; intracellular signal transduction; membrane; metal ion binding; phospholipid binding; protein kinase C activity,PF00130;PF00169;PF00069;,1.00E-89,CHOYP_KPCD3.1.1,,,,,,,KPCD3_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556] comp116175_c1_seq1,294,43.1973,0.36856998,3,20,,5.00E-14,O96017,Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2),Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2),GO:0005524; GO:0006975; GO:0000086; GO:0016605; GO:0051301; GO:0044257; GO:0006302; GO:0008630; GO:0046872; GO:0045893; GO:0046777; GO:0042803; GO:0004674; GO:0050821; GO:0042176; GO:0090399; GO:0010332; GO:0072428; GO:0090307; GO:0006351,"ATP binding; DNA damage induced protein phosphorylation; G2/M transition of mitotic cell cycle; PML body; cell division; cellular protein catabolic process; double-strand break repair; intrinsic apoptotic signaling pathway in response to DNA damage; metal ion binding; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; protein stabilization; regulation of protein catabolic process; replicative senescence; response to gamma radiation; signal transduction involved in intra-S DNA damage checkpoint; spindle assembly involved in mitosis; transcription, DNA-dependent",PF00498;PF00069;,,,,,,,,,CHK2_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to doxorubicin [GO:1902520]; response to gamma radiation [GO:0010332]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]; transcription, DNA-templated [GO:0006351]" comp116175_c2_seq1,491,40.1222,0.87016591,12,47,,,,,,,,,3.00E-13,CHOYP_KPCD1.1.1,,,,,,,,, comp116176_c0_seq1,447,48.5459,0.53994761,17,23,,6.00E-34,Q6P6Y1,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,,,,4.00E-30,CHOYP_K1468.1.1,,,,,,,K1468_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp116190_c0_seq1,556,36.3309,0.27519852,16,31,,5.00E-42,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,4.00E-18,CHOYP_SACS.11.17,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp116208_c0_seq2,762,42.7822,0.70322702,0,0,,2.00E-20,Q6NWH1,DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32),DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32),GO:0080008; GO:0016567,Cul4-RING ubiquitin ligase complex; protein ubiquitination,PF00400;,,,,,,,,,DCA10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp116234_c0_seq1,1134,36.8607,0.62603468,67,332,,8.00E-73,Q99MD8,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116239_c0_seq1,212,43.8679,0.29556624,5,5,,5.00E-07,Q7T3P8,Protein fem-1 homolog C (FEM1c) (FEM1-gamma),Protein fem-1 homolog C (FEM1c) (FEM1-gamma),GO:0005737; GO:0016567,cytoplasm; protein ubiquitination,PF12796;,,,,,,,,,FEM1C_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp116239_c1_seq1,725,41.5172,0.28873232,17,81,,1.00E-19,Q02357,Ankyrin-1 (ANK-1) (Erythrocyte ankyrin),Ankyrin-1 (ANK-1) (Erythrocyte ankyrin),GO:0030863; GO:0048821; GO:0016020; GO:0015672; GO:0006779; GO:0016529; GO:0007165; GO:0014731,cortical cytoskeleton; erythrocyte development; membrane; monovalent inorganic cation transport; porphyrin-containing compound biosynthetic process; sarcoplasmic reticulum; signal transduction; spectrin-associated cytoskeleton,PF12796;PF00531;PF00791;,,,,,,,,,ANK1_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; iron ion homeostasis [GO:0055072]; monovalent inorganic cation transport [GO:0015672]; porphyrin-containing compound biosynthetic process [GO:0006779]; protein targeting to plasma membrane [GO:0072661]; signal transduction [GO:0007165] comp116241_c0_seq1,344,40.407,0.14291753,15,10,,,,,,,,,2.00E-18,CHOYP_LOC100889557.1.1,,,,,,,,, comp116250_c0_seq1,547,41.8647,0.41800292,0,5,,3.00E-32,P11837,G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis),G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis),GO:0005524; GO:0000086; GO:0051301; GO:0007059; GO:0043987; GO:0007067; GO:0005634; GO:0045840; GO:0004674,ATP binding; G2/M transition of mitotic cell cycle; cell division; chromosome segregation; histone H3-S10 phosphorylation; mitosis; nucleus; positive regulation of mitosis; protein serine/threonine kinase activity,PF00069;,,,,,,,,,NIMA_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-S10 phosphorylation [GO:0043987]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic nuclear division [GO:0045840]; protein phosphorylation [GO:0006468] comp116250_c0_seq2,789,42.3321,0.51656578,7,17,,7.00E-131,Q86SG6,Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a),Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a),GO:0005524; GO:0005737; GO:0005856; GO:0046872; GO:0009887; GO:0072372; GO:0004674; GO:0035330,ATP binding; cytoplasm; cytoskeleton; metal ion binding; organ morphogenesis; primary cilium; protein serine/threonine kinase activity; regulation of hippo signaling cascade,PF00069;PF00415;,2.00E-145,CHOYP_LOC100375651.1.1,,,,,,,NEK8_HUMAN,Homo sapiens (Human),determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; organ morphogenesis [GO:0009887]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] comp116252_c0_seq1,766,44.6475,0.57904769,10,25,,1.00E-90,A6QL92,Solute carrier family 35 member F5,Solute carrier family 35 member F5,GO:0016021; GO:0006810,integral to membrane; transport,,7.00E-49,CHOYP_LOC100875839.1.1,,,,,,,S35F5_BOVIN,Bos taurus (Bovine),transport [GO:0006810] comp116267_c0_seq1,409,44.0098,0.56687116,6,0,,5.00E-10,Q3TGF2,Protein FAM107B,Protein FAM107B,,,PF06625;,,,,,,,,,F107B_MOUSE,Mus musculus (Mouse),sensory perception of sound [GO:0007605] comp116269_c0_seq1,1186,41.1467,0.55848538,7,15,,2.00E-19,Q9H7F0,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00689;PF00690;PF00122;PF12409;,1.00E-15,CHOYP_LOC660831.1.1,,,,,,,AT133_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874] comp116270_c0_seq1,270,46.2963,0.56547463,0,0,,3.00E-19,Q9EQG6,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0030165; GO:0016482; GO:0005829; GO:0016021; GO:0005770; GO:0038180; GO:0010976; GO:0043234; GO:0019901; GO:0019887,PDZ domain binding; cytoplasmic transport; cytosol; integral to membrane; late endosome; nerve growth factor signaling pathway; positive regulation of neuron projection development; protein complex; protein kinase binding; protein kinase regulator activity,PF12796;PF07693;,,,,,,,,,KDIS_RAT,Rattus norvegicus (Rat),activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976] comp116270_c0_seq2,1161,49.4401,0.62054194,0,0,,1.00E-19,Q96KQ7,Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a),Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a),GO:0006306; GO:0010424; GO:0005694; GO:0009566; GO:0046976; GO:0046974; GO:0000122; GO:0005634; GO:0035265; GO:0018027; GO:0006275; GO:0007286; GO:0007130; GO:0008270,DNA methylation; DNA methylation on cytosine within a CG sequence; chromosome; fertilization; histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); negative regulation of transcription from RNA polymerase II promoter; nucleus; organ growth; peptidyl-lysine dimethylation; regulation of DNA replication; spermatid development; synaptonemal complex assembly; zinc ion binding,PF12796;PF05033;PF00856;,5.00E-116,CHOYP_LOC100700010.1.1,,,,,,,EHMT2_HUMAN,Homo sapiens (Human),cellular response to starvation [GO:0009267]; DNA methylation [GO:0006306]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; regulation of DNA replication [GO:0006275]; regulation of signal transduction by p53 class mediator [GO:1901796] comp116270_c0_seq3,1402,48.8588,0.55016759,7,14,,4.00E-158,Q7T163,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0016021; GO:0005770; GO:0007399,integral to membrane; late endosome; nervous system development,PF00023;PF12796;PF07693;,,,,,,,,,KDIS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859] comp116285_c0_seq1,2484,43.5588,0.53798978,173,38,,1.00E-129,P00529,Tyrosine-protein kinase transforming protein ros (EC 2.7.10.1),Tyrosine-protein kinase transforming protein ros (EC 2.7.10.1),GO:0005524; GO:0016020; GO:0018108; GO:0004714; GO:0007169,ATP binding; membrane; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;,1.00E-127,CHOYP_AGAP_AGAP000015.1.1,,,,,,,ROS_AVISU,UR2 sarcoma virus (UR2SV) (Avian sarcoma virus (strain UR2)),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp116285_c1_seq1,448,44.4196,0.50040776,34,0,,8.00E-08,Q78DX7,Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase),Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase),GO:0005524; GO:0016049; GO:0008283; GO:0002066; GO:0016021; GO:0010629; GO:0005886; GO:0004713; GO:0070372; GO:0032006; GO:0010966; GO:0007283; GO:0004714,ATP binding; cell growth; cell proliferation; columnar/cuboidal epithelial cell development; integral to membrane; negative regulation of gene expression; plasma membrane; protein tyrosine kinase activity; regulation of ERK1 and ERK2 cascade; regulation of TOR signaling cascade; regulation of phosphate transport; spermatogenesis; transmembrane receptor protein tyrosine kinase activity,PF00041;PF07714;,,,,,,,,,ROS1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; columnar/cuboidal epithelial cell development [GO:0002066]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphate transport [GO:0010966]; regulation of TOR signaling [GO:0032006]; signal transduction by protein phosphorylation [GO:0023014]; spermatogenesis [GO:0007283] comp116285_c1_seq2,419,46.5394,0.40068068,19,0,,6.00E-07,P08941,Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase),Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase),GO:0005524; GO:0016049; GO:0008283; GO:0002066; GO:0016021; GO:0005886; GO:0004713; GO:0070372; GO:0032006; GO:0004714; GO:0007169,ATP binding; cell growth; cell proliferation; columnar/cuboidal epithelial cell development; integral to membrane; plasma membrane; protein tyrosine kinase activity; regulation of ERK1 and ERK2 cascade; regulation of TOR signaling cascade; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF07714;,,,,,,,,,ROS1_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; columnar/cuboidal epithelial cell development [GO:0002066]; protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp116293_c0_seq1,294,47.9592,0.95200779,7,43,,4.00E-12,Q86GF7,Crustapain (EC 3.4.22.-) (NsCys),Crustapain (EC 3.4.22.-) (NsCys),GO:0030574; GO:0008234; GO:0007586; GO:0005576; GO:0030163; GO:0006508,collagen catabolic process; cysteine-type peptidase activity; digestion; extracellular region; protein catabolic process; proteolysis,PF08246;PF00112;,,,,,,,,,CRUST_PANBO,Pandalus borealis (Northern red shrimp),collagen catabolic process [GO:0030574]; digestion [GO:0007586]; protein catabolic process [GO:0030163] comp116297_c0_seq1,225,46.6667,0.49310065,1,7,,1.00E-18,Q8NB14,Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38),Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP38_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp116297_c2_seq1,527,44.9715,0.33889724,17,13,,7.00E-26,Q9P2H5,Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35),Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,2.00E-15,CHOYP_BRAFLDRAFT_125949.1.1,,,,,,,UBP35_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp116300_c0_seq1,728,38.0495,1.40836732,2,58,,3.00E-26,Q9JHE4,Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase),Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase),GO:0000139; GO:0006682; GO:0001733; GO:0016021; GO:0042552; GO:0007283,Golgi membrane; galactosylceramide biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane; myelination; spermatogenesis,PF06990;,,,,,,,,,G3ST1_MOUSE,Mus musculus (Mouse),galactosylceramide biosynthetic process [GO:0006682]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283] comp116306_c1_seq2,526,39.924,0.20699211,24,36,,9.00E-18,Q9NP66,High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1),High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1),GO:0003677; GO:0016568; GO:0006325; GO:0045665; GO:0000122; GO:0005634; GO:0003700; GO:0006351,"DNA binding; chromatin modification; chromatin organization; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00505;,,,,,,,,,HM20A_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116326_c0_seq1,797,41.5307,0.64406881,20,32,,2.00E-116,Q8N2K1,Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2),Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2),GO:0005524; GO:0005789; GO:0016021; GO:0006986; GO:0004842,ATP binding; endoplasmic reticulum membrane; integral to membrane; response to unfolded protein; ubiquitin-protein ligase activity,PF00179;,2.00E-81,CHOYP_UB2J2.1.2,,,,,,,UB2J2_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; response to unfolded protein [GO:0006986] comp116328_c0_seq2,462,52.381,0.3525804,11,13,,7.00E-13,Q9VU84,Drebrin-like protein,Drebrin-like protein (Actin binding protein 1),GO:0051015; GO:0022416; GO:0005737; GO:0005856; GO:0005547; GO:0005546; GO:0001786,"actin filament binding; chaeta development; cytoplasm; cytoskeleton; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding",PF00241;PF14604;,3.00E-12,CHOYP_SRC8.1.1,,,,,,,DBNL_DROME,Drosophila melanogaster (Fruit fly),chaeta development [GO:0022416]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; terminal button organization [GO:0072553] comp116330_c0_seq2,393,45.0382,0.5034533,3,37,,5.00E-07,Q9P2K9,Patched domain-containing protein 2 (Protein dispatched homolog 3),Protein dispatched homolog 3 (Patched domain-containing protein 2),GO:0042632; GO:0005783; GO:0008158; GO:0016021; GO:0031965; GO:0032368; GO:0007224,cholesterol homeostasis; endoplasmic reticulum; hedgehog receptor activity; integral to membrane; nuclear membrane; regulation of lipid transport; smoothened signaling pathway,PF03176;PF02460;,,,,,,,,,PTHD2_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; regulation of lipid transport [GO:0032368]; smoothened signaling pathway [GO:0007224] comp116339_c0_seq1,583,42.024,0.51042237,28,21,,1.00E-78,Q92831,Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF),Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF),GO:0031672; GO:0005671; GO:0031674; GO:0018076; GO:0007219; GO:0000125; GO:0042641; GO:0007050; GO:0032869; GO:0006338; GO:0004861; GO:0043966; GO:0004402; GO:0000776; GO:0004468; GO:0019048; GO:0008285; GO:0045736; GO:0045944; GO:0032403; GO:0019901; GO:0010835; GO:0003713; GO:0006361; GO:0006367,A band; Ada2/Gcn5/Ada3 transcription activator complex; I band; N-terminal peptidyl-lysine acetylation; Notch signaling pathway; PCAF complex; actomyosin; cell cycle arrest; cellular response to insulin stimulus; chromatin remodeling; cyclin-dependent protein serine/threonine kinase inhibitor activity; histone H3 acetylation; histone acetyltransferase activity; kinetochore; lysine N-acetyltransferase activity; modulation by virus of host morphology or physiology; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; positive regulation of transcription from RNA polymerase II promoter; protein complex binding; protein kinase binding; regulation of protein ADP-ribosylation; transcription coactivator activity; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter,PF00583;PF00439;PF06466;,2.00E-92,CHOYP_KAT2B.1.1,,,,,,,KAT2B_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to parathyroid hormone stimulus [GO:0071374]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; memory [GO:0007613]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of chromatin binding [GO:0035563]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vasodilation [GO:0045909]; protein acetylation [GO:0006473]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp116343_c0_seq1,635,42.6772,0.69281218,5,7,,4.00E-47,Q9Y3D2,"Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)","Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)",GO:0003779; GO:0030041; GO:0005739; GO:0033743; GO:0030091; GO:0003700; GO:0008270,actin binding; actin filament polymerization; mitochondrion; peptide-methionine (R)-S-oxide reductase activity; protein repair; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF01641;,,,,,,,,,MSRB2_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp116348_c0_seq1,390,48.9744,0.90321684,6,134,,4.00E-21,Q8MRC9,Putative polypeptide N-acetylgalactosaminyltransferase 9 (pp-GaNTase 9) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9),Putative polypeptide N-acetylgalactosaminyltransferase 9 (pp-GaNTase 9) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9),GO:0000139; GO:0016021; GO:0032504; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; multicellular organism reproduction; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,,,,,,,,,GALT9_DROME,Drosophila melanogaster (Fruit fly),multicellular organism reproduction [GO:0032504]; protein O-linked glycosylation [GO:0006493] comp116351_c0_seq1,1093,46.2946,0.60003498,20,14,,4.00E-126,Q27433,Mechanosensory protein 2,Mechanosensory protein 2,GO:0016021; GO:0007638; GO:0032589,integral to membrane; mechanosensory behavior; neuron projection membrane,PF01145;,4.00E-155,CHOYP_LOC582981.1.1,1.00E-57,ruditapes_c11694,,,,,MEC2_CAEEL,Caenorhabditis elegans,mechanosensory behavior [GO:0007638]; response to mechanical stimulus [GO:0009612] comp116351_c0_seq2,532,43.985,0.62591047,2,0,,,,,,,,,4.00E-69,CHOYP_LOC582981.1.1,,,,,,,,, comp116353_c0_seq1,697,45.4806,0.64185323,0,0,,3.00E-21,Q7Z9I2,Uncharacterized oxidoreductase C663.09c (EC 1.-.-.-),Uncharacterized oxidoreductase C663.09c (EC 1.-.-.-),GO:0005829; GO:0005634; GO:0016491,cytosol; nucleus; oxidoreductase activity,PF00106;,,,,,,,,,YCP9_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp116353_c0_seq4,713,45.4418,0.6578637,0,0,,1.00E-28,P21158,C-factor (C signal),C-factor (C signal),GO:0005576; GO:0055114; GO:0016491; GO:0030435,extracellular region; oxidation-reduction process; oxidoreductase activity; sporulation resulting in formation of a cellular spore,PF00106;,,,,,,,,,CSGA_MYXXA,Myxococcus xanthus,sporulation resulting in formation of a cellular spore [GO:0030435] comp116360_c0_seq1,886,37.1332,0.43424775,416,1898,,3.00E-49,Q32PE0,"DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (RPB6 homolog)","DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (RPB6 homolog)",GO:0003677; GO:0005665; GO:0003899; GO:0006366,"DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; transcription from RNA polymerase II promoter",PF01192;,6.00E-50,CHOYP_RPAB2.1.2,8.00E-59,ruditapes_c14954,,,,,RPAB2_BOVIN,Bos taurus (Bovine),transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360] comp116377_c0_seq1,376,41.2234,0.31680896,8,26,,2.00E-11,Q6P5H6,FERM domain-containing protein 5,FERM domain-containing protein 5,GO:0005737; GO:0005856; GO:0019898,cytoplasm; cytoskeleton; extrinsic to membrane,PF08736;PF09380;PF00373;PF09379;,,,,,,,,,FRMD5_MOUSE,Mus musculus (Mouse), comp116377_c1_seq1,838,40.6921,0.46727997,22,55,,2.00E-47,Q96NE9,FERM domain-containing protein 6 (Willin),FERM domain-containing protein 6 (Willin),GO:0003383; GO:0043296; GO:0034613; GO:0005856; GO:0005739; GO:0005886; GO:0032970,apical constriction; apical junction complex; cellular protein localization; cytoskeleton; mitochondrion; plasma membrane; regulation of actin filament-based process,PF09380;PF00373;PF09379;,5.00E-102,CHOYP_LOC592633.1.1,,,,,,,FRMD6_HUMAN,Homo sapiens (Human),apical constriction [GO:0003383]; cellular protein localization [GO:0034613]; regulation of actin filament-based process [GO:0032970] comp116390_c0_seq1,248,43.9516,0.92285867,5,37,,2.00E-07,Q99489,D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),GO:0019478; GO:0003884; GO:0008445; GO:0006533; GO:0006531; GO:0048037; GO:0007625; GO:0042445; GO:0007320; GO:0005777,D-amino acid catabolic process; D-amino-acid oxidase activity; D-aspartate oxidase activity; aspartate catabolic process; aspartate metabolic process; cofactor binding; grooming behavior; hormone metabolic process; insemination; peroxisome,PF01266;,,,,,,,,,OXDD_HUMAN,Homo sapiens (Human),aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; D-amino acid catabolic process [GO:0019478]; glyoxylate metabolic process [GO:0046487]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insemination [GO:0007320] comp116397_c0_seq1,562,42.7046,0.54751493,5,0,,1.00E-18,A8DYE2,Transient receptor potential cation channel trpm,"Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)",GO:0005261; GO:0034703; GO:0016049; GO:0070838; GO:0010960; GO:0046873; GO:0007005; GO:0055069,cation channel activity; cation channel complex; cell growth; divalent metal ion transport; magnesium ion homeostasis; metal ion transmembrane transporter activity; mitochondrion organization; zinc ion homeostasis,PF00520;PF16519;,,,,,,,,,TRPCG_DROME,Drosophila melanogaster (Fruit fly),cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069] comp116397_c0_seq2,544,41.5441,0.59984479,0,0,,5.00E-14,Q93971,Transient receptor potential channel (Abnormal gonad development protein 2),Transient receptor potential channel (Abnormal gonad development protein 2),GO:0008324; GO:0030421; GO:0008406; GO:0016021; GO:0005216; GO:0007067; GO:0005886,cation transmembrane transporter activity; defecation; gonad development; integral to membrane; ion channel activity; mitosis; plasma membrane,PF00520;,,,,,,,,,TRPG_CAEEL,Caenorhabditis elegans,cation transport [GO:0006812]; defecation [GO:0030421]; gonad development [GO:0008406]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067] comp116397_c1_seq1,388,45.8763,0.5096994,35,10,,1.00E-09,Q9ESQ5,Transient receptor potential cation channel subfamily M member 4 (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (MLS2s) (Melastatin-like 2),Transient receptor potential cation channel subfamily M member 4 (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (MLS2s) (Melastatin-like 2),GO:0005524; GO:0005794; GO:0005227; GO:0005262; GO:0002407; GO:0005783; GO:0016021; GO:0005886; GO:0090263; GO:0008284; GO:0016925; GO:0002724,ATP binding; Golgi apparatus; calcium activated cation channel activity; calcium channel activity; dendritic cell chemotaxis; endoplasmic reticulum; integral to membrane; plasma membrane; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell proliferation; protein sumoylation; regulation of T cell cytokine production,PF00520;,,,,,,,,,TRPM4_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; cardiac conduction [GO:0061337]; dendritic cell chemotaxis [GO:0002407]; negative regulation of bone mineralization [GO:0030502]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of atrial cardiac muscle cell action potential [GO:1903949]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of heart rate [GO:0010460]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of regulation of vascular smooth muscle cell membrane depolarization [GO:1904199]; positive regulation of vasoconstriction [GO:0045907]; protein sumoylation [GO:0016925]; regulation of T cell cytokine production [GO:0002724]; vasoconstriction [GO:0042310] comp116412_c0_seq1,432,46.9907,0.50535186,3,29,,3.00E-38,Q9QYP2,Cadherin EGF LAG seven-pass G-type receptor 2 (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) (Fragment),Cadherin EGF LAG seven-pass G-type receptor 2 (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) (Fragment),GO:0004930; GO:0005509; GO:0048813; GO:0007156; GO:0016021; GO:0007218; GO:0005886; GO:0022407; GO:0007283,G-protein coupled receptor activity; calcium ion binding; dendrite morphogenesis; homophilic cell adhesion; integral to membrane; neuropeptide signaling pathway; plasma membrane; regulation of cell-cell adhesion; spermatogenesis,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,3.00E-31,CHOYP_LOC100704608.1.1,,,,,,,CELR2_RAT,Rattus norvegicus (Rat),cell surface receptor signaling pathway [GO:0007166]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of cell-cell adhesion [GO:0022407]; spermatogenesis [GO:0007283] comp116412_c1_seq2,774,48.3204,0.55412648,8,69,,2.00E-51,Q9V5N8,Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),GO:0004930; GO:0007464; GO:0048057; GO:0016055; GO:0007411; GO:0005509; GO:0016339; GO:0050839; GO:0005911; GO:0048813; GO:0070593; GO:0007156; GO:0005887; GO:0016319; GO:0030178; GO:0007218; GO:0016318; GO:0030177; GO:0005057; GO:0050770; GO:0090175; GO:0051963; GO:0035159; GO:0007367; GO:0004888,"G-protein coupled receptor activity; R3/R4 cell fate commitment; R3/R4 development; Wnt receptor signaling pathway; axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell junction; dendrite morphogenesis; dendrite self-avoidance; homophilic cell adhesion; integral to plasma membrane; mushroom body development; negative regulation of Wnt receptor signaling pathway; neuropeptide signaling pathway; ommatidial rotation; positive regulation of Wnt receptor signaling pathway; receptor signaling protein activity; regulation of axonogenesis; regulation of establishment of planar polarity; regulation of synapse assembly; regulation of tube length, open tracheal system; segment polarity determination; transmembrane signaling receptor activity",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,STAN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]" comp116418_c0_seq1,298,44.2953,0.4215273,41,0,,3.00E-11,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp116434_c0_seq1,398,38.6935,0.27143028,0,0,,2.00E-18,P83104,Putative mitogen-activated protein kinase kinase kinase 7-like (EC 2.7.11.25),Putative mitogen-activated protein kinase kinase kinase 7-like (EC 2.7.11.25),GO:0005524; GO:0004709; GO:0000165; GO:0000186; GO:0046872; GO:0018108; GO:0004713,ATP binding; MAP kinase kinase kinase activity; MAPK cascade; activation of MAPKK activity; metal ion binding; peptidyl-tyrosine phosphorylation; protein tyrosine kinase activity,PF00069;,4.00E-48,CHOYP_BRAF.2.3,,,,,,,M3K7L_DROME,Drosophila melanogaster (Fruit fly),protein phosphorylation [GO:0006468] comp116434_c0_seq2,603,40.2985,0.53262933,5,6,,1.00E-88,P10533,Serine/threonine-protein kinase-transforming protein Rmil (EC 2.7.11.1),Serine/threonine-protein kinase-transforming protein Rmil (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF07714;,1.00E-56,CHOYP_BRAF.3.3,,,,,,,RMIL_AVII1,Avian retrovirus IC10, comp116435_c0_seq2,844,45.4976,0.35130315,0,0,,4.00E-75,Q9H330,Transmembrane protein 245 (Protein CG-2),Transmembrane protein 245 (Protein CG-2),GO:0016021,integral to membrane,PF01594;,2.00E-63,CHOYP_BRAFLDRAFT_85004.1.1,,,,,,,TM245_HUMAN,Homo sapiens (Human), comp116435_c0_seq5,1379,46.7005,0.32608713,0,0,,8.00E-107,D3ZXD8,Transmembrane protein 245,Transmembrane protein 245,GO:0016021,integral to membrane,PF01594;,,,,,,,,,TM245_RAT,Rattus norvegicus (Rat), comp116437_c0_seq1,792,42.9293,0.41679873,11,102,,1.00E-128,Q9HD40,O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein),O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein),GO:0005737; GO:0005634; GO:0030170; GO:0001514; GO:0097056; GO:0000049; GO:0016785,"cytoplasm; nucleus; pyridoxal phosphate binding; selenocysteine incorporation; selenocysteinyl-tRNA(Sec) biosynthetic process; tRNA binding; transferase activity, transferring selenium-containing groups",PF05889;,2.00E-43,CHOYP_SPCS.1.1,,,,,,,SPCS_HUMAN,Homo sapiens (Human),selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056] comp116443_c0_seq1,1051,37.6784,0.76453558,80,116,,2.00E-136,P25228,Ras-related protein Rab-3,Ras-related protein Rab-3,GO:0005525; GO:0030054; GO:0006887; GO:0048790; GO:0007269; GO:0048786; GO:0015031; GO:0007264; GO:0008021; GO:0016192,GTP binding; cell junction; exocytosis; maintenance of presynaptic active zone structure; neurotransmitter secretion; presynaptic active zone; protein transport; small GTPase mediated signal transduction; synaptic vesicle; vesicle-mediated transport,PF00071;,3.00E-143,CHOYP_LOC100533330.1.2,,,,,,,RAB3_DROME,Drosophila melanogaster (Fruit fly),cytoskeletal matrix organization at active zone [GO:0048789]; exocytosis [GO:0006887]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic membrane [GO:0031630]; vesicle-mediated transport [GO:0016192] comp116457_c0_seq2,265,47.1698,0.61291195,21,0,,2.00E-20,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,1.00E-21,CHOYP_RN213.9.13,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp116458_c0_seq1,343,48.688,1.38551235,40,34,,1.00E-38,P86221,Tubulin beta-4B chain (Tubulin beta-2C chain) (Fragments),Tubulin beta-4B chain (Tubulin beta-2C chain) (Fragments),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;,4.00E-54,CHOYP_TBB.6.7,2.00E-68,ruditapes_c27968,,,,,TBB4B_MESAU,Mesocricetus auratus (Golden hamster),microtubule-based process [GO:0007017] comp116459_c0_seq1,1310,39.6183,1.09579454,745,17592,,2.00E-62,P07291,"Myosin essential light chain, striated adductor muscle (E-LC) (Sulfhydryl light chain) (SHLC)","Myosin essential light chain, striated adductor muscle (E-LC) (Sulfhydryl light chain) (SHLC)",GO:0005509; GO:0016459,calcium ion binding; myosin complex,PF13499;,2.00E-51,CHOYP_MLE.6.9,2.00E-138,ruditapes2_c281,,,,,MLE_AEQIR,Argopecten irradians (Bay scallop) (Aequipecten irradians), comp116469_c0_seq1,659,42.4886,0.20353665,19,17,,3.00E-27,A8C752,Thyroid adenoma-associated protein homolog,Thyroid adenoma-associated protein homolog,,,PF10350;,,,,,,,,,THADA_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), comp116472_c0_seq1,502,43.4263,0.63590644,27,0,,,,,,,,,4.00E-18,CHOYP_LOC100369720.1.1,,,,,,,,, comp116478_c0_seq1,2171,38.5537,0.89798469,6828,31297,,7.00E-39,P00185,Cytochrome P450 1A1 (CYP1A1) (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-C) (Cytochrome P450MT2) [Cleaved into: Cytochrome P450MT2A; Cytochrome P450MT2B],Cytochrome P450 1A1 (CYP1A1) (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-C) (Cytochrome P450MT2) [Cleaved into: Cytochrome P450MT2A; Cytochrome P450MT2B],GO:0042904; GO:0007568; GO:0009308; GO:0070330; GO:0043010; GO:0008283; GO:0009804; GO:0032451; GO:0019341; GO:0048565; GO:0017144; GO:0009792; GO:0005789; GO:0019899; GO:0016711; GO:0009812; GO:0020037; GO:0070365; GO:0050665; GO:0017143; GO:0005506; GO:0060137; GO:0031966; GO:0005739; GO:0016679; GO:0006778; GO:1900087; GO:0046677; GO:0046685; GO:0042493; GO:0032094; GO:0009635; GO:0055093; GO:0001666; GO:0010041; GO:0032496; GO:0009624; GO:0014070; GO:0009615; GO:0033189; GO:0009611; GO:0008395; GO:0070576,"9-cis-retinoic acid biosynthetic process; aging; amine metabolic process; aromatase activity; camera-type eye development; cell proliferation; coumarin metabolic process; demethylase activity; dibenzo-p-dioxin catabolic process; digestive tract development; drug metabolic process; embryo development ending in birth or egg hatching; endoplasmic reticulum membrane; enzyme binding; flavonoid 3'-monooxygenase activity; flavonoid metabolic process; heme binding; hepatocyte differentiation; hydrogen peroxide biosynthetic process; insecticide metabolic process; iron ion binding; maternal process involved in parturition; mitochondrial membrane; mitochondrion; oxidoreductase activity, acting on diphenols and related substances as donors; porphyrin-containing compound metabolic process; positive regulation of G1/S transition of mitotic cell cycle; response to antibiotic; response to arsenic-containing substance; response to drug; response to food; response to herbicide; response to hyperoxia; response to hypoxia; response to iron(III) ion; response to lipopolysaccharide; response to nematode; response to organic cyclic compound; response to virus; response to vitamin A; response to wounding; steroid hydroxylase activity; vitamin D 24-hydroxylase activity",PF00067;,,,,,,,,,CP1A1_RAT,Rattus norvegicus (Rat),9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; developmental process [GO:0032502]; dibenzo-p-dioxin catabolic process [GO:0019341]; dibenzo-p-dioxin metabolic process [GO:0018894]; digestive tract development [GO:0048565]; drug metabolic process [GO:0017144]; embryo development ending in birth or egg hatching [GO:0009792]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; liver development [GO:0001889]; maternal process involved in parturition [GO:0060137]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611] comp116481_c1_seq1,286,39.1608,0.27455693,7,0,,2.00E-09,O43422,52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0),52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12),GO:0003677; GO:0046872; GO:0008285; GO:0005634; GO:0006950; GO:0007165,DNA binding; metal ion binding; negative regulation of cell proliferation; nucleus; response to stress; signal transduction,PF05699;PF14291;PF05485;,1.00E-21,CHOYP_LOC100680230.1.1,,,,,,,P52K_HUMAN,Homo sapiens (Human),negative regulation of cell proliferation [GO:0008285]; response to stress [GO:0006950]; signal transduction [GO:0007165] comp116483_c0_seq1,957,44.4096,0.40570344,57,99,,4.00E-36,P30432,Furin-like protease 2 (Furin-2) (EC 3.4.21.75),Furin-like protease 2 (Furin-2) (EC 3.4.21.75),GO:0016021; GO:0005886; GO:0006508; GO:0004252,integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity,PF14843;PF01483;PF00082;PF16470;,7.00E-12,CHOYP_LOC100202203.1.1,,,,,,,FUR2_DROME,Drosophila melanogaster (Fruit fly),negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906] comp116486_c0_seq1,833,35.4142,0.38568313,3168,7400,,4.00E-07,Q1LUK1,Protein QIL1,MICOS complex subunit MIC13,,,PF15884;,,,,,,,,,QIL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cristae formation [GO:0042407] comp116497_c0_seq1,1291,40.976,0.49686457,22,181,,1.00E-34,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp116509_c0_seq1,898,42.4276,0.48069514,22,81,,4.00E-95,O97902,"Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)","Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)",GO:0008060; GO:0060271; GO:0005737; GO:0016020; GO:0005543; GO:0043547; GO:0032312; GO:0008270,ARF GTPase activator activity; cilium morphogenesis; cytoplasm; membrane; phospholipid binding; positive regulation of GTPase activity; regulation of ARF GTPase activity; zinc ion binding,PF12796;PF01412;PF00169;PF00018;,4.00E-72,CHOYP_BRAFLDRAFT_199108.2.2,,,,,,,ASAP1_BOVIN,Bos taurus (Bovine),cilium morphogenesis [GO:0060271] comp116514_c0_seq1,790,48.6076,0.4087973,14,88,,3.00E-49,Q2HXL6,"ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)","ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)",GO:0005509; GO:0005788; GO:0006516; GO:0004569; GO:0004571; GO:0016020; GO:0043161; GO:0006986,"calcium ion binding; endoplasmic reticulum lumen; glycoprotein catabolic process; glycoprotein endo-alpha-1,2-mannosidase activity; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; membrane; proteasomal ubiquitin-dependent protein catabolic process; response to unfolded protein",PF01532;PF02225;,1.00E-19,CHOYP_EDEM3.1.1,,,,,,,EDEM3_MOUSE,Mus musculus (Mouse),endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp116519_c0_seq2,851,45.5934,0.5937787,9,17,,2.00E-32,Q9NIV1,Eukaryotic translation initiation factor 2-alpha kinase (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (DmPEK) (PEK) (PERK),Eukaryotic translation initiation factor 2-alpha kinase (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (DmPEK) (PEK) (PERK),GO:0005524; GO:0004686; GO:0005789; GO:0016021; GO:0010389; GO:0006417; GO:0006986,ATP binding; elongation factor-2 kinase activity; endoplasmic reticulum membrane; integral to membrane; regulation of G2/M transition of mitotic cell cycle; regulation of translation; response to unfolded protein,PF00069;,,,,,,,,,E2AK3_DROME,Drosophila melanogaster (Fruit fly),ER overload response [GO:0006983]; negative regulation of translation [GO:0017148]; positive regulation of autophagy [GO:0010508]; protein phosphorylation [GO:0006468]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; response to unfolded protein [GO:0006986] comp116520_c0_seq1,974,41.3758,0.34082433,51,106,,1.00E-103,Q8VHQ4,Ras-related protein Rab-40C (SOCS box-containing protein RAR3),Ras-related protein Rab-40C (SOCS box-containing protein RAR3),GO:0005525; GO:0005886; GO:0015031; GO:0016567; GO:0007264,GTP binding; plasma membrane; protein transport; protein ubiquitination; small GTPase mediated signal transduction,PF00071;PF07525;,2.00E-102,CHOYP_LOC100372140.1.1,,,,,,,RB40C_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264] comp116521_c0_seq1,1088,44.5772,1.12353077,21,358,,1.00E-13,Q5YW75,Ectoine hydroxylase (EC 1.17.-.-),Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase),GO:0016725,"oxidoreductase activity, acting on CH or CH2 groups",PF05721;,,,3.00E-27,ruditapes2_c2597,,,,,ECTD_NOCFA,Nocardia farcinica (strain IFM 10152),ectoine catabolic process [GO:0042400] comp116521_c0_seq2,623,46.7095,1.19882082,0,0,,,,,,,,,6.00E-23,CHOYP_LOC100641267.2.2,,,,,,,,, comp116525_c0_seq1,983,41.3021,0.52860651,1250,5038,,6.00E-86,Q9BYD3,"39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4)","39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF00573;,4.00E-21,CHOYP_DWIL_GK24328.1.1,1.00E-24,ruditapes_c13775,,,,,RM04_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412] comp116526_c0_seq1,638,39.0282,0.83328962,61,41,,7.00E-21,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp11652_c0_seq1,206,51.9417,0.50630124,5,0,,2.00E-17,Q9CWL2,Zinc finger protein castor homolog 1 (Castor-related protein),Zinc finger protein castor homolog 1 (Castor-related protein),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,1.00E-25,CHOYP_LOC100749506.1.1,,,,,,,CASZ1_MOUSE,Mus musculus (Mouse),"central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]" comp116531_c0_seq1,496,34.0726,1.32813479,3209,190,,,,,,,,,6.00E-47,CHOYP_NEMVEDRAFT_V1G142226.1.1,,,,,,,,, comp116538_c0_seq1,1931,38.6328,0.54421371,1334,8045,,9.00E-172,Q6P8G1,Interleukin enhancer-binding factor 2 homolog,Interleukin enhancer-binding factor 2 homolog,GO:0005524; GO:0003677; GO:0003725; GO:0006955; GO:0005730; GO:0045893; GO:0006351; GO:0016740,"ATP binding; DNA binding; double-stranded RNA binding; immune response; nucleolus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; transferase activity",PF07528;,5.00E-144,CHOYP_BRAFLDRAFT_76728.1.1,,,,,,,ILF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"immune response [GO:0006955]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp116539_c1_seq1,307,49.1857,0.45394734,9,4,,3.00E-15,F4JLI5,Xanthine dehydrogenase 2 (AtXDH2) (EC 1.17.1.4),Xanthine dehydrogenase 2 (AtXDH2) (EC 1.17.1.4),GO:0051537; GO:0008762; GO:0009055; GO:0050660; GO:0005506; GO:0004854; GO:0046110,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; xanthine dehydrogenase activity; xanthine metabolic process",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH2_ARATH,Arabidopsis thaliana (Mouse-ear cress),xanthine metabolic process [GO:0046110] comp116544_c0_seq1,487,45.5852,0.43571612,3,21,,7.00E-06,P83344,Putative beta-D-xylosidase (EC 3.2.1.-) (PpAz152) (Fragment),Putative beta-D-xylosidase (EC 3.2.1.-) (PpAz152) (Fragment),GO:0005975; GO:0016798; GO:0004553,"carbohydrate metabolic process; hydrolase activity, acting on glycosyl bonds; hydrolase activity, hydrolyzing O-glycosyl compounds",PF14310;PF01915;,,,,,,,,,XYNB_PRUPE,Prunus persica (Peach) (Amygdalus persica),carbohydrate metabolic process [GO:0005975] comp116544_c1_seq1,275,41.4545,0.52588819,0,6,,1.00E-15,Q5ATH9,"Exo-1,4-beta-xylosidase bxlB (EC 3.2.1.37) (1,4-beta-D-xylan xylohydrolase bxlB) (Beta-xylosidase bxlB) (Xylobiase bxlB)","Exo-1,4-beta-xylosidase bxlB (EC 3.2.1.37) (1,4-beta-D-xylan xylohydrolase bxlB) (Beta-xylosidase bxlB) (Xylobiase bxlB)",GO:0046556; GO:0005576; GO:0009044; GO:0045493; GO:0042285,"alpha-N-arabinofuranosidase activity; extracellular region; xylan 1,4-beta-xylosidase activity; xylan catabolic process; xylosyltransferase activity",PF14310;PF00933;PF01915;,,,,,,,,,BXLB_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),arabinan catabolic process [GO:0031222]; xylan catabolic process [GO:0045493]; xylan metabolic process [GO:0045491] comp116555_c0_seq1,528,40.3409,0.37678198,12,12,,,,,,,,,1.00E-12,CHOYP_BRAFLDRAFT_67258.17.18,,,,,,,,, comp116560_c0_seq1,1217,39.6878,0.98615054,487,8618,,1.00E-09,Q6DHN0,Transmembrane protein 53,Transmembrane protein 53,GO:0016021,integral to membrane,PF05705;,,,,,,,,,TMM53_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp116562_c0_seq1,237,50.211,0.53877586,6,10,,5.00E-15,Q5FWM8,Integral membrane protein GPR180,Integral membrane protein GPR180,GO:0007186; GO:0016021; GO:0019236,G-protein coupled receptor signaling pathway; integral to membrane; response to pheromone,PF10192;,,,,,,,,,GP180_XENLA,Xenopus laevis (African clawed frog),G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] comp116562_c0_seq2,353,48.1586,0.5465307,4,31,,7.00E-17,Q86V85,Integral membrane protein GPR180 (Intimal thickness-related receptor),Integral membrane protein GPR180 (Intimal thickness-related receptor),GO:0007186; GO:0016021; GO:0019236,G-protein coupled receptor signaling pathway; integral to membrane; response to pheromone,PF10192;,2.00E-32,CHOYP_BRAFLDRAFT_244305.1.1,,,,,,,GP180_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] comp116567_c0_seq1,2093,32.6804,0.66468221,2233,8275,,,,,,,,,,,4.00E-35,ruditapes_c180,,,,,,, comp116574_c0_seq1,1472,39.6739,0.83021033,2120,11694,,3.00E-13,P53567,CCAAT/enhancer-binding protein gamma (C/EBP gamma),CCAAT/enhancer-binding protein gamma (C/EBP gamma),GO:0030183; GO:0003690; GO:0043353; GO:0001889; GO:0016071; GO:0042267; GO:0043433; GO:0005634; GO:0043388; GO:0045739; GO:0045078; GO:0051091; GO:0046982; GO:0006357; GO:0043565; GO:0003700; GO:0008134; GO:0006351,"B cell differentiation; double-stranded DNA binding; enucleate erythrocyte differentiation; liver development; mRNA metabolic process; natural killer cell mediated cytotoxicity; negative regulation of sequence-specific DNA binding transcription factor activity; nucleus; positive regulation of DNA binding; positive regulation of DNA repair; positive regulation of interferon-gamma biosynthetic process; positive regulation of sequence-specific DNA binding transcription factor activity; protein heterodimerization activity; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription, DNA-dependent",PF07716;,1.00E-16,CHOYP_GPTC4.1.2,1.00E-135,ruditapes_c1117,,,,,CEBPG_HUMAN,Homo sapiens (Human),B cell differentiation [GO:0030183]; enucleate erythrocyte differentiation [GO:0043353]; immune response [GO:0006955]; liver development [GO:0001889]; mRNA metabolic process [GO:0016071]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA repair [GO:0045739]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp116583_c2_seq1,756,43.5185,0.43666435,23,48,,1.00E-70,P11915,Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X),Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X),GO:0006869; GO:0005739; GO:0005777; GO:0010893; GO:0033814; GO:0032934,lipid transport; mitochondrion; peroxisome; positive regulation of steroid biosynthetic process; propanoyl-CoA C-acyltransferase activity; sterol binding,PF02036;PF02803;PF00108;,2.00E-67,CHOYP_NEMVEDRAFT_V1G173950.1.1,,,,,,,NLTP_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular response to cholesterol [GO:0071397]; metabolic process [GO:0008152]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol import [GO:1904109]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid biosynthetic process [GO:0010893]; response to estradiol [GO:0032355]; response to luteinizing hormone [GO:0034699] comp116586_c0_seq1,673,33.7296,0.32926306,9,74,,1.00E-06,Q99M85,Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt),Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,SCRT1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; transcription, DNA-templated [GO:0006351]" comp116586_c1_seq1,523,38.8145,0.81620236,5,28,,3.00E-07,Q96MU6,Zinc finger protein 778,Zinc finger protein 778,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN778_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116590_c0_seq1,530,36.9811,0.77607542,24182,17831,,9.00E-10,Q7YRK5,"Cytochrome c oxidase subunit 7C, mitochondrial (Cytochrome c oxidase polypeptide VIIc)","Cytochrome c oxidase subunit 7C, mitochondrial (Cytochrome c oxidase polypeptide VIIc)",GO:0004129; GO:0016021; GO:0005743,cytochrome-c oxidase activity; integral to membrane; mitochondrial inner membrane,PF02935;,,,,,,,,,COX7C_TARSY,Tarsius syrichta (Philippine tarsier), comp116598_c0_seq2,657,41.4003,0.57621501,0,0,,,,,,,,,,,4.00E-42,ruditapes2_c2672,,,,,,, comp116601_c0_seq1,408,60.2941,1.08144489,0,86,,2.00E-73,O42867,60S ribosomal protein L23,,GO:0002181; GO:0022625; GO:0005739; GO:0005634; GO:0003735,cytoplasmic translation; cytosolic large ribosomal subunit; mitochondrion; nucleus; structural constituent of ribosome,,5.00E-34,CHOYP_RL23.8.11,4.00E-14,ruditapes_lrc33777,,,,,RL23_SCHPO,, comp116611_c0_seq1,973,38.7461,0.63595139,70324,172508,,3.00E-27,Q06646,"ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P2) (ATPase protein 9) (ATPase subunit c)","ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P2) (ATPase protein 9) (ATPase subunit c)",GO:0015991; GO:0015986; GO:0015078; GO:0016021; GO:0008289; GO:0031966; GO:0045263; GO:0045471,"ATP hydrolysis coupled proton transport; ATP synthesis coupled proton transport; hydrogen ion transmembrane transporter activity; integral to membrane; lipid binding; mitochondrial membrane; proton-transporting ATP synthase complex, coupling factor F(o); response to ethanol",PF00137;,2.00E-31,CHOYP_LOC100914229.1.1,2.00E-74,ruditapes2_lrc4103,,,,,AT5G2_RAT,Rattus norvegicus (Rat),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; response to ethanol [GO:0045471] comp116612_c0_seq1,875,45.1429,0.40643418,64031,248819,,2.00E-140,Q6P0V6,60S ribosomal protein L8,60S ribosomal protein L8,GO:0015934; GO:0019843; GO:0003735; GO:0006412,large ribosomal subunit; rRNA binding; structural constituent of ribosome; translation,PF00181;PF03947;,0,CHOYP_RL8.10.10,0,ruditapes_lrc32341,,,,,RL8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cytoplasmic translation [GO:0002181] comp116614_c0_seq1,808,40.7178,0.5710597,29,143,,2.00E-16,Q5TM19,NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1),NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1),GO:0071222; GO:0032088; GO:0031665; GO:0034122; GO:0032720; GO:0005634,cellular response to lipopolysaccharide; negative regulation of NF-kappaB transcription factor activity; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of toll-like receptor signaling pathway; negative regulation of tumor necrosis factor production; nucleus,,,,,,,,,,IKBL1_MACMU,Macaca mulatta (Rhesus macaque),cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720] comp116618_c0_seq1,2987,41.7476,0.48236218,64164,367513,,0,P29691,Elongation factor 2 (EF-2),Elongation factor 2 (EF-2),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,0,CHOYP_EF2.4.5,5.00E-125,ruditapes2_c46,,,,,EF2_CAEEL,Caenorhabditis elegans,translation [GO:0006412] comp116621_c0_seq1,821,40.8039,0.58714373,28993,177934,,3.00E-86,P42577,Soma ferritin (EC 1.16.3.1),Soma ferritin (EC 1.16.3.1),GO:0006879; GO:0005737; GO:0008199; GO:0004322; GO:0006826,cellular iron ion homeostasis; cytoplasm; ferric iron binding; ferroxidase activity; iron ion transport,PF00210;,2.00E-87,CHOYP_FRIS.9.11,4.00E-113,ruditapes_c3824,,,,,FRIS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] comp116623_c0_seq1,757,43.461,0.45220064,37318,140314,,7.00E-91,Q90Z10,60S ribosomal protein L13,60S ribosomal protein L13,GO:0051726; GO:0005840; GO:0003735; GO:0006412,regulation of cell cycle; ribosome; structural constituent of ribosome; translation,PF01294;,5.00E-101,CHOYP_RL13.4.4,2.00E-116,ruditapes2_lrc5088,,,,,RL13_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of cell cycle [GO:0051726]; translation [GO:0006412] comp116626_c0_seq1,1625,39.5692,0.88188156,134585,277902,,3.00E-96,P61314,60S ribosomal protein L15,60S ribosomal protein L15,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00827;,2.00E-58,CHOYP_RL15.1.3,9.00E-144,ruditapes_c14,,,,,RL15_RAT,Rattus norvegicus (Rat),cytoplasmic translation [GO:0002181]; response to ethanol [GO:0045471] comp116629_c0_seq1,579,41.7962,0.51725475,25875,87586,,2.00E-30,P67985,60S ribosomal protein L22 (Heparin-binding protein HBp15),60S ribosomal protein L22 (Heparin-binding protein HBp15),GO:0003723; GO:0046632; GO:0022625; GO:0008201; GO:0003735; GO:0006412,RNA binding; alpha-beta T cell differentiation; cytosolic large ribosomal subunit; heparin binding; structural constituent of ribosome; translation,PF01776;,2.00E-48,CHOYP_RL22.4.4,2.00E-96,ruditapes_c7060,,,,,RL22_PIG,Sus scrofa (Pig),alpha-beta T cell differentiation [GO:0046632]; cytoplasmic translation [GO:0002181] comp116630_c0_seq1,1447,45.6807,0.43751051,105458,290902,,5.00E-143,A3RLT6,40S ribosomal protein SA,40S ribosomal protein SA,GO:0022627; GO:0000028; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; ribosomal small subunit assembly; structural constituent of ribosome; translation,PF16122;PF00318;,1.00E-175,CHOYP_RSSA.1.10,0,ruditapes2_c1008,,,,,RSSA_PINFU,Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata),ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] comp116632_c0_seq1,2145,32.4009,0.62544945,117510,1757,,2.00E-36,Q8LX26,Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III),Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III),GO:0019646; GO:0004129; GO:0016021; GO:0005743; GO:0045277; GO:0008535,aerobic electron transport chain; cytochrome-c oxidase activity; integral to membrane; mitochondrial inner membrane; respiratory chain complex IV; respiratory chain complex IV assembly,PF00510;,,,,,,,,,COX3_LEMCA,Lemur catta (Ring-tailed lemur),aerobic electron transport chain [GO:0019646]; respiratory chain complex IV assembly [GO:0008535] comp116632_c1_seq1,1775,33.8028,0.57865405,229106,5257,,3.00E-159,P12700,Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I),Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I),GO:0009060; GO:0004129; GO:0009055; GO:0020037; GO:0016021; GO:0005506; GO:0005743; GO:0006119; GO:0070469,aerobic respiration; cytochrome-c oxidase activity; electron carrier activity; heme binding; integral to membrane; iron ion binding; mitochondrial inner membrane; oxidative phosphorylation; respiratory chain,PF00115;,4.00E-56,CHOYP_COX1.4.15,2.00E-88,ruditapes2_c1885,,,,,COX1_PARLI,Paracentrotus lividus (Common sea urchin),aerobic respiration [GO:0009060]; oxidative phosphorylation [GO:0006119] comp116635_c0_seq1,1887,42.3423,0.44060967,56280,198430,,0,Q25117,"ATP synthase subunit beta, mitochondrial (EC 3.6.3.14)","ATP synthase subunit beta, mitochondrial (EC 3.6.3.14)",GO:0005524; GO:0015991; GO:0015986; GO:0005743; GO:0046933; GO:0045261,"ATP binding; ATP hydrolysis coupled proton transport; ATP synthesis coupled proton transport; mitochondrial inner membrane; proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATP synthase complex, catalytic core F(1)",PF00006;PF02874;,0,CHOYP_ATPB.1.1,0,ruditapes2_lrc3391,,,,,ATPB_HEMPU,Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986] comp116636_c0_seq1,880,37.8409,0.57842211,7533,126398,,1.00E-72,Q9UUY8,Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6),Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0005829; GO:0046872; GO:0005758; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cytosol; metal ion binding; mitochondrial intermembrane space; nucleoside diphosphate kinase activity,PF00334;,5.00E-70,CHOYP_AGAP_AGAP007120.1.1,1.00E-94,ruditapes_lrc15447,,,,,NDK_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),CDP phosphorylation [GO:0061508]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228] comp116638_c0_seq1,1263,36.7379,0.58719725,89572,51480,,3.00E-89,Q6P823,Histone H3.3,Histone H3.3,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;,1.00E-123,CHOYP_BRAFLDRAFT_124122.1.1,2.00E-150,ruditapes_lrc32855,,,,,H33_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp116639_c0_seq2,906,38.9625,1.10787663,766,2156,,,,,,,,,,,3.00E-20,ruditapes2_lrc4331,,,,,,, comp116647_c0_seq1,1573,42.2759,0.64101327,29,185,,8.00E-37,O15075,Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1),Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1),GO:0005524; GO:0048675; GO:0007417; GO:0021952; GO:0048813; GO:0016197; GO:0030900; GO:0005887; GO:0035556; GO:0001764; GO:0004672; GO:0004674; GO:0005057; GO:0009615,ATP binding; axon extension; central nervous system development; central nervous system projection neuron axonogenesis; dendrite morphogenesis; endosomal transport; forebrain development; integral to plasma membrane; intracellular signal transduction; neuron migration; protein kinase activity; protein serine/threonine kinase activity; receptor signaling protein activity; response to virus,PF03607;PF00069;,6.00E-66,CHOYP_BRAFLDRAFT_71623.1.2,,,,,,,DCLK1_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; central nervous system development [GO:0007417]; central nervous system projection neuron axonogenesis [GO:0021952]; dendrite morphogenesis [GO:0048813]; endosomal transport [GO:0016197]; forebrain development [GO:0030900]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615] comp116651_c1_seq1,626,39.1374,0.63444576,14,19,,2.00E-33,Q6IQX7,Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2),Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2),GO:0032580; GO:0050510; GO:0047238; GO:0016021; GO:0046872; GO:0016758,"Golgi cisterna membrane; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; integral to membrane; metal ion binding; transferase activity, transferring hexosyl groups",PF05679;,,,,,,,,,CHSS2_MOUSE,Mus musculus (Mouse),chondroitin sulfate biosynthetic process [GO:0030206] comp116654_c0_seq1,534,45.1311,0.60375441,17103,66955,,6.00E-14,P62864,40S ribosomal protein S30,40S ribosomal protein S30,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF04758;,5.00E-42,CHOYP_AGAP_AGAP004136.3.3,6.00E-121,ruditapes_lrc32418,,,,,RS30_RAT,Rattus norvegicus (Rat),translation [GO:0006412] comp116667_c0_seq2,761,36.3995,0.88000152,0,8,,8.00E-07,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp116667_c0_seq3,761,36.9251,0.817097,5,6,,9.00E-09,Q24307,Apoptosis 2 inhibitor (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2) (dIAP2),Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2),GO:0050829; GO:0043066; GO:0043154; GO:0061057; GO:0006964; GO:0033160; GO:0070534; GO:0007423; GO:0008270,"defense response to Gram-negative bacterium; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidoglycan recognition protein signaling pathway; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; positive regulation of protein import into nucleus, translocation; protein K63-linked ubiquitination; sensory organ development; zinc ion binding",PF00653;,,,,,,,,,IAP2_DROME,Drosophila melanogaster (Fruit fly),"defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]" comp116674_c1_seq1,594,40.5724,0.08246732,26,32,,3.00E-12,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116681_c0_seq1,846,45.7447,0.47812012,47,60,,3.00E-52,Q9UBS9,SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1),SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1),GO:0016021; GO:0016020; GO:0007275; GO:0001503; GO:0032967; GO:0045669; GO:0046850; GO:0005791; GO:0030867,integral to membrane; membrane; multicellular organismal development; ossification; positive regulation of collagen biosynthetic process; positive regulation of osteoblast differentiation; regulation of bone remodeling; rough endoplasmic reticulum; rough endoplasmic reticulum membrane,PF07738;,5.00E-13,CHOYP_C8H1ORF9.1.1,,,,,,,SUCO_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850] comp116682_c1_seq2,701,45.6491,0.52563654,31,15,,1.00E-97,P0CY46,Epidermal growth factor receptor (Egfr) (EC 2.7.10.1),Epidermal growth factor receptor (Egfr) (EC 2.7.10.1),GO:0005524; GO:0016021; GO:0007275; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00757;PF14843;PF07714;PF01030;,1.00E-88,CHOYP_EGFR.1.3,,,1.00E-71,EW778003.p.cg.6,1,,EGFR_APIME,Apis mellifera (Honeybee),multicellular organism development [GO:0007275]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp116684_c0_seq1,1089,35.7208,0.68972216,3992,13970,,3.00E-25,Q1HPL8,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,GO:0005743; GO:0055114; GO:0070469,mitochondrial inner membrane; oxidation-reduction process; respiratory chain,PF10249;,,,1.00E-25,ruditapes2_c575,,,,,NDUBA_BOMMO,Bombyx mori (Silk moth),oxidation-reduction process [GO:0055114] comp116685_c0_seq1,1839,33.2246,0.55219738,2137,10075,,7.00E-25,Q9C005,Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L),Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L),GO:0005794; GO:0048188; GO:0016197; GO:0051568; GO:0006355; GO:0005802; GO:0006351,"Golgi apparatus; Set1C/COMPASS complex; endosomal transport; histone H3-K4 methylation; regulation of transcription, DNA-dependent; trans-Golgi network; transcription, DNA-dependent",PF05186;,6.00E-22,CHOYP_BRAFLDRAFT_202721.2.2,5.00E-65,ruditapes_c10134,,,,,DPY30_HUMAN,Homo sapiens (Human),"chromatin silencing at telomere [GO:0006348]; endosomal transport [GO:0016197]; histone H3-K4 methylation [GO:0051568]; transcription, DNA-templated [GO:0006351]" comp116694_c0_seq1,428,46.9626,0.43141828,0,8,,9.00E-41,Q9EP89,"Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)","Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)",GO:0016787; GO:0005739,hydrolase activity; mitochondrion,PF00144;,,,,,,,,,LACTB_MOUSE,Mus musculus (Mouse), comp116703_c0_seq1,896,33.817,0.66601236,8165,20892,,7.00E-20,O94581,Cytochrome c oxidase subunit 6B (Cytochrome c oxidase polypeptide VIb),Cytochrome c oxidase subunit 6B (Cytochrome c oxidase polypeptide VIb),GO:0009060; GO:0004129; GO:0005829; GO:0005751; GO:0033617; GO:0005634,aerobic respiration; cytochrome-c oxidase activity; cytosol; mitochondrial respiratory chain complex IV; mitochondrial respiratory chain complex IV assembly; nucleus,PF02297;,,,,,,,,,COX12_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mitochondrial respiratory chain complex IV assembly [GO:0033617] comp116716_c0_seq1,698,40.6877,0.90202687,5441,12807,,2.00E-16,Q9U5P1,Fatty acid-binding protein (allergen Lep d 13),Fatty acid-binding protein (allergen Lep d 13),GO:0005737; GO:0008289; GO:0005215,cytoplasm; lipid binding; transporter activity,PF00061;,,,1.00E-24,ruditapes_lrc32741,,,,,FABP_LEPDS,Lepidoglyphus destructor (Storage mite) (Glycyphagus destructor), comp116727_c0_seq1,1884,39.4904,0.32082741,9001,30237,,0,O02654,Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase),Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase),GO:0006096; GO:0000287; GO:0004634; GO:0000015,glycolysis; magnesium ion binding; phosphopyruvate hydratase activity; phosphopyruvate hydratase complex,PF00113;PF03952;,0,CHOYP_ENO.1.2,9.00E-113,ruditapes_c2730,,,,,ENO_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),glycolytic process [GO:0006096] comp116729_c0_seq1,1067,43.8613,0.50824608,41,118,,9.00E-92,B1H1P9,Lysosomal acid phosphatase (LAP) (EC 3.1.3.2),Lysosomal acid phosphatase (LAP) (EC 3.1.3.2),GO:0003993; GO:0016021; GO:0043202; GO:0005765,acid phosphatase activity; integral to membrane; lysosomal lumen; lysosomal membrane,PF00328;,,,,,,,,,PPAL_XENLA,Xenopus laevis (African clawed frog), comp116732_c0_seq1,576,39.9306,0.39269628,19,71,,2.00E-20,Q96GE5,Zinc finger protein 799 (Zinc finger protein 842),Zinc finger protein 799 (Zinc finger protein 842),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN799_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116735_c0_seq1,667,45.4273,0.67397941,33,73,,1.00E-10,Q32KN2,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3,GO:0016021; GO:0005741; GO:0097345; GO:0035694; GO:0043065,integral to membrane; mitochondrial outer membrane; mitochondrial outer membrane permeabilization; mitochondrial protein catabolic process; positive regulation of apoptotic process,PF06553;,,,,,,,,,BNIP3_BOVIN,Bos taurus (Bovine),mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrial protein catabolic process [GO:0035694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of programmed cell death [GO:0043068] comp116740_c0_seq3,1235,44.7773,0.52251144,75,29,,5.00E-58,Q9H8X2,"Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (IPK1 homolog) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase)","Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (IPK1 homolog) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase)",GO:0005524; GO:0005829; GO:0035299; GO:0043647; GO:0052746; GO:0005654,ATP binding; cytosol; inositol pentakisphosphate 2-kinase activity; inositol phosphate metabolic process; inositol phosphorylation; nucleoplasm,PF06090;,,,,,,,,,IPPK_HUMAN,Homo sapiens (Human),inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; inositol phosphorylation [GO:0052746]; mitophagy in response to mitochondrial depolarization [GO:0098779] comp116751_c0_seq1,1105,41.448,0.46626463,33,55,,6.00E-16,Q5BQN8,Centromere protein J (CENP-J),Centromere protein J (CENP-J),GO:0005814; GO:0005874; GO:0046599,centriole; microtubule; regulation of centriole replication,PF07202;,8.00E-31,CHOYP_CENPJ.1.1,,,,,,,CENPJ_PANTR,Pan troglodytes (Chimpanzee),cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; regulation of centriole replication [GO:0046599] comp116764_c0_seq1,826,44.9153,0.50873002,0,0,,1.00E-19,Q99LC9,Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1),Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1),GO:0005524; GO:0042623; GO:0005829; GO:0005778; GO:0016561; GO:0050821,"ATP binding; ATPase activity, coupled; cytosol; peroxisomal membrane; protein import into peroxisome matrix, translocation; protein stabilization",PF00004;,6.00E-50,CHOYP_ATAD1.1.1,,,,,,,PEX6_MOUSE,Mus musculus (Mouse),"peroxisome organization [GO:0007031]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]" comp116764_c0_seq2,1442,40.9154,0.35377574,29,67,,4.00E-130,Q505J9,ATPase family AAA domain-containing protein 1 (EC 3.6.1.3) (Thorase),ATPase family AAA domain-containing protein 1 (EC 3.6.1.3) (Thorase),GO:0005524; GO:0016887; GO:0030054; GO:0007612; GO:0007613; GO:0005739; GO:0051967; GO:0005778; GO:0002092; GO:0045211,"ATP binding; ATPase activity; cell junction; learning; memory; mitochondrion; negative regulation of synaptic transmission, glutamatergic; peroxisomal membrane; positive regulation of receptor internalization; postsynaptic membrane",PF00004;,3.00E-12,CHOYP_LOC582354.1.1,,,,,,,ATAD1_RAT,Rattus norvegicus (Rat),"cytoplasmic microtubule organization [GO:0031122]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; positive regulation of receptor internalization [GO:0002092]" comp116790_c0_seq1,468,38.4615,0.28982953,17,71,,2.00E-25,O00628,Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),GO:0005829; GO:0001958; GO:0008611; GO:0006635; GO:0001764; GO:0005782; GO:0005053; GO:0042803; GO:0016558,cytosol; endochondral ossification; ether lipid biosynthetic process; fatty acid beta-oxidation; neuron migration; peroxisomal matrix; peroxisome matrix targeting signal-2 binding; protein homodimerization activity; protein import into peroxisome matrix,PF00400;,4.00E-11,CHOYP_LOC100370808.1.1,,,,,,,PEX7_HUMAN,Homo sapiens (Human),endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] comp116797_c1_seq1,642,43.6137,0.74961763,18,49,,3.00E-24,Q924S7,"Sprouty-related, EVH1 domain-containing protein 2 (Spred-2)","Sprouty-related, EVH1 domain-containing protein 2 (Spred-2)",GO:0031410; GO:0000188; GO:0007275; GO:0010801; GO:0005886; GO:0043517; GO:0030291; GO:0090311; GO:0030658,"cytoplasmic vesicle; inactivation of MAPK activity; multicellular organismal development; negative regulation of peptidyl-threonine phosphorylation; plasma membrane; positive regulation of DNA damage response, signal transduction by p53 class mediator; protein serine/threonine kinase inhibitor activity; regulation of protein deacetylation; transport vesicle membrane",PF05210;PF00568;,4.00E-31,CHOYP_SPRE2.1.1,,,,,,,SPRE2_MOUSE,Mus musculus (Mouse),"inactivation of MAPK activity [GO:0000188]; multicellular organism development [GO:0007275]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of protein deacetylation [GO:0090311]" comp116802_c0_seq1,251,34.2629,0.40887615,12,5,,,,,,,,,5.00E-13,CHOYP_LOC100378309.1.1,,,,,,,,, comp116804_c0_seq1,1219,37.1616,0.81285573,4591,44,male>female,,,,,,,,,,2.00E-68,ruditapes_c2032,,,,,,, comp116810_c0_seq2,924,44.2641,0.64147093,40,55,,1.00E-08,Q9MAQ3,Putative ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (AtUBP11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11),Putative ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (AtUBP11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11),GO:0008234; GO:0016579; GO:0004221; GO:0006511,cysteine-type peptidase activity; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF06337;PF00443;,,,,,,,,,UBP11_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp116812_c0_seq1,864,31.0185,1.35254551,12,187,,1.00E-07,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp116818_c0_seq2,992,38.6089,0.77186242,269,3637,,1.00E-103,Q5R9C7,Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18),Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18),GO:0005789; GO:0016021; GO:0006508; GO:0008236; GO:0006465,endoplasmic reticulum membrane; integral to membrane; proteolysis; serine-type peptidase activity; signal peptide processing,PF00717;,9.00E-150,CHOYP_CPT1A.1.1,,,,,,,SC11A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),signal peptide processing [GO:0006465] comp116823_c0_seq1,680,33.2353,0.81071604,384,2407,,2.00E-22,B6NK32,LYR motif-containing protein 9,LYR motif-containing protein 9,,,PF05347;,,,2.00E-15,ruditapes_c20623,,,,,U631_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus), comp116828_c0_seq1,797,37.7666,0.49389998,1,0,,2.00E-53,Q8N7Q3,Zinc finger protein 676,Zinc finger protein 676,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;PF13465;,,,,,,,,,ZN676_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116828_c0_seq2,746,37.9357,0.52311018,0,0,,1.00E-55,Q8TF32,Zinc finger protein 431,Zinc finger protein 431,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN431_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116841_c1_seq1,283,41.3428,1.34998715,1,56,,2.00E-10,Q6P1G6,Protein FAM167A,Protein FAM167A,,,PF11652;,,,1.00E-18,ruditapes_c13390,,,,,F167A_MOUSE,Mus musculus (Mouse), comp116842_c0_seq1,220,42.2727,0.62196407,2,0,,,,,,,,,8.00E-22,CHOYP_LOC100905760.1.1,,,,,,,,, comp116842_c1_seq1,780,43.4615,0.65657947,42,22,,2.00E-85,Q5U4S8,Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),GO:0005794; GO:0000139; GO:0008120; GO:0046479; GO:0016021; GO:0007275,Golgi apparatus; Golgi membrane; ceramide glucosyltransferase activity; glycosphingolipid catabolic process; integral to membrane; multicellular organismal development,PF13506;,,,,,,,,,CEGTB_XENLA,Xenopus laevis (African clawed frog),glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275] comp116848_c0_seq1,1587,42.5961,0.32424288,60,138,,2.00E-50,Q66HY8,Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-),Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-),GO:0016831; GO:0019752; GO:0030170,carboxy-lyase activity; carboxylic acid metabolic process; pyridoxal phosphate binding,PF00282;,2.00E-28,CHOYP_AAEL_AAEL010939.1.1,,,,,,,PDXD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carboxylic acid metabolic process [GO:0019752] comp116853_c0_seq1,478,45.8159,1.08517005,5,0,,1.00E-12,Q8R4G9,Neuronal acetylcholine receptor subunit alpha-3,Neuronal acetylcholine receptor subunit alpha-3,GO:0015464; GO:0004889; GO:0005892; GO:0007171; GO:0035095; GO:0030054; GO:0007626; GO:0045211; GO:0014056; GO:0048814; GO:0060079; GO:0006940; GO:0060084; GO:0007271,"acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; activation of transmembrane receptor protein tyrosine kinase activity; behavioral response to nicotine; cell junction; locomotory behavior; postsynaptic membrane; regulation of acetylcholine secretion, neurotransmission; regulation of dendrite morphogenesis; regulation of excitatory postsynaptic membrane potential; regulation of smooth muscle contraction; synaptic transmission involved in micturition; synaptic transmission, cholinergic",PF02931;PF02932;,,,,,,,,,ACHA3_MOUSE,Mus musculus (Mouse),"activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; excitatory postsynaptic potential [GO:0060079]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; regulation of smooth muscle contraction [GO:0006940]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission involved in micturition [GO:0060084]" comp116853_c0_seq2,659,43.5508,1.15497058,25,0,,2.00E-10,Q27218,Acetylcholine receptor subunit beta-type lev-1 (Levamisole-resistant protein 1),Acetylcholine receptor subunit beta-type lev-1 (Levamisole-resistant protein 1),GO:0015464; GO:0004889; GO:0022848; GO:0030054; GO:0016021; GO:0043005; GO:0043025; GO:0045211; GO:0040012; GO:0046662,acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-gated cation channel activity; cell junction; integral to membrane; neuron projection; neuronal cell body; postsynaptic membrane; regulation of locomotion; regulation of oviposition,PF02931;PF02932;,,,,,,,,,ACH7_CAEEL,Caenorhabditis elegans,"inorganic cation transmembrane transport [GO:0098662]; neuromuscular synaptic transmission [GO:0007274]; regulation of locomotion [GO:0040012]; regulation of oviposition [GO:0046662]; response to nicotine [GO:0035094]; synaptic transmission, cholinergic [GO:0007271]" comp116855_c0_seq1,541,34.0111,1.10745571,8,3,,7.00E-07,Q49I35,Galectin-1 (Gal-1) (Lectin galactoside-binding soluble 1),Galectin-1 (Gal-1) (Lectin galactoside-binding soluble 1),GO:0006915; GO:0030246; GO:0016936; GO:0005578,apoptotic process; carbohydrate binding; galactoside binding; proteinaceous extracellular matrix,PF00337;,,,,,,,,,LEG1_PIG,Sus scrofa (Pig),apoptotic process [GO:0006915] comp116864_c0_seq2,837,44.086,0.54169437,10,31,,3.00E-27,Q9Z2F6,B-cell lymphoma 3 protein homolog (BCL-3),B-cell lymphoma 3 protein homolog (BCL-3),GO:0032996; GO:0033257; GO:0003677; GO:0030330; GO:0007249; GO:0042088; GO:0045064; GO:0019730; GO:0042742; GO:0042832; GO:0030198; GO:0002268; GO:0002467; GO:0002455; GO:0042771; GO:0002315; GO:0043066; GO:0045415; GO:0045892; GO:0042536; GO:0005634; GO:0048471; GO:0032729; GO:0045082; GO:0045944; GO:0045727; GO:0000060; GO:0051101; GO:0042345; GO:0010225; GO:0009615; GO:0003700; GO:0048536; GO:0006351,"Bcl3-Bcl10 complex; Bcl3/NF-kappaB2 complex; DNA binding; DNA damage response, signal transduction by p53 class mediator; I-kappaB kinase/NF-kappaB cascade; T-helper 1 type immune response; T-helper 2 cell differentiation; antimicrobial humoral response; defense response to bacterium; defense response to protozoan; extracellular matrix organization; follicular dendritic cell differentiation; germinal center formation; humoral immune response mediated by circulating immunoglobulin; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; marginal zone B cell differentiation; negative regulation of apoptotic process; negative regulation of interleukin-8 biosynthetic process; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor biosynthetic process; nucleus; perinuclear region of cytoplasm; positive regulation of interferon-gamma production; positive regulation of interleukin-10 biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translation; protein import into nucleus, translocation; regulation of DNA binding; regulation of NF-kappaB import into nucleus; response to UV-C; response to virus; sequence-specific DNA binding transcription factor activity; spleen development; transcription, DNA-dependent",PF00023;PF12796;,,,,,,,,,BCL3_MOUSE,Mus musculus (Mouse),"antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; protein import into nucleus, translocation [GO:0000060]; regulation of apoptotic process [GO:0042981]; regulation of DNA binding [GO:0051101]; regulation of NF-kappaB import into nucleus [GO:0042345]; response to UV-C [GO:0010225]; response to virus [GO:0009615]; spleen development [GO:0048536]; T-helper 1 type immune response [GO:0042088]; T-helper 2 cell differentiation [GO:0045064]; transcription, DNA-templated [GO:0006351]" comp116869_c0_seq1,1102,40.6534,0.83669098,1658,3040,,4.00E-20,O16277,Putative histone H1.6 (Histone H1-like protein 6),Putative histone H1.6 (Histone H1-like protein 6),GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00538;,3.00E-29,CHOYP_ALS2.2.3,2.00E-49,ruditapes_c16308,,,,,H16_CAEEL,Caenorhabditis elegans,nucleosome assembly [GO:0006334] comp116872_c0_seq1,302,44.3709,0.82170392,4,38,,8.00E-30,Q9UPP2,IQ motif and SEC7 domain-containing protein 3,IQ motif and SEC7 domain-containing protein 3,GO:0005086; GO:0030036; GO:0030054; GO:0005737; GO:0060077; GO:0005634; GO:0005543; GO:0045211; GO:0032012,ARF guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cell junction; cytoplasm; inhibitory synapse; nucleus; phospholipid binding; postsynaptic membrane; regulation of ARF protein signal transduction,PF01369;,,,,,,,,,IQEC3_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] comp116872_c0_seq2,287,42.5087,0.77587149,2,34,,4.00E-38,Q8R0S2,IQ motif and SEC7 domain-containing protein 1,IQ motif and SEC7 domain-containing protein 1,GO:0005086; GO:0030036; GO:0030054; GO:0005634; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cell junction; nucleus; phospholipid binding; regulation of ARF protein signal transduction,PF01369;,2.00E-43,CHOYP_SIZ.1.1,,,,,,,IQEC1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] comp116874_c0_seq1,871,38.2319,0.31729901,1213,5858,,4.00E-50,Q9VJ38,"39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13)","39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF00572;,1.00E-14,CHOYP_LOC661769.1.1,3.00E-45,ruditapes_c25682,,,,,RM13_DROME,Drosophila melanogaster (Fruit fly),sensory perception of pain [GO:0019233]; translation [GO:0006412] comp116887_c0_seq1,495,40.404,0.80519809,5,0,,2.00E-11,O94443,Uncharacterized exonuclease C637.09 (EC 3.1.-.-),Uncharacterized exonuclease C637.09 (EC 3.1.-.-),GO:0008408; GO:0034476; GO:0000467; GO:0003676; GO:0005634; GO:0034415,"3'-5' exonuclease activity; U5 snRNA 3'-end processing; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleic acid binding; nucleus; tRNA 3'-trailer cleavage, exonucleolytic",PF00929;,,,,,,,,,YFE9_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA processing [GO:0006396]; tRNA 3'-trailer cleavage, exonucleolytic [GO:0034415]; U5 snRNA 3'-end processing [GO:0034476]" comp116887_c0_seq2,492,39.6341,0.79091236,0,23,,1.00E-20,A0PJM3,Putative exonuclease GOR-like protein (EC 3.1.-.-) (RNA exonuclease 1 homolog-like 2),,GO:0004527; GO:0003676; GO:0090305,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,,,,,,,,,,GORL_HUMAN,, comp116890_c0_seq1,653,43.6447,0.58497454,0,0,,1.00E-35,Q15262,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0005912; GO:0030424; GO:0016477; GO:0009986; GO:0005911; GO:0034644; GO:0034614; GO:0030425; GO:0048041; GO:0005887; GO:0031256; GO:0045786; GO:0030336; GO:0010839; GO:0045892; GO:0043025; GO:0001750; GO:0034394; GO:0007179; GO:0005001,"adherens junction; axon; cell migration; cell surface; cell-cell junction; cellular response to UV; cellular response to reactive oxygen species; dendrite; focal adhesion assembly; integral to plasma membrane; leading edge membrane; negative regulation of cell cycle; negative regulation of cell migration; negative regulation of keratinocyte proliferation; negative regulation of transcription, DNA-dependent; neuronal cell body; photoreceptor outer segment; protein localization to cell surface; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein tyrosine phosphatase activity",PF00041;PF07679;PF00629;PF00102;,3.00E-59,CHOYP_LOC100883586.1.1,,,,,,,PTPRK_HUMAN,Homo sapiens (Human),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp116890_c0_seq2,1025,44,0.73434401,27,57,,2.00E-33,P23468,Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48),GO:0050839; GO:0007157; GO:0005887; GO:0030182; GO:0050775; GO:0097105; GO:0005102; GO:0005001; GO:0007185,cell adhesion molecule binding; heterophilic cell-cell adhesion; integral to plasma membrane; neuron differentiation; positive regulation of dendrite morphogenesis; presynaptic membrane assembly; receptor binding; transmembrane receptor protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase signaling pathway,PF00041;PF07679;PF00102;,,,,,,,,,PTPRD_HUMAN,Homo sapiens (Human),chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] comp116890_c1_seq1,654,43.578,0.54949793,24,37,,1.00E-65,P43378,Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2),Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2),GO:0005737; GO:0004726,cytoplasm; non-membrane spanning protein tyrosine phosphatase activity,PF00650;PF00102;,,,,,,,,,PTN9_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470] comp116891_c0_seq1,432,45.3704,0.32125238,13,46,,4.00E-37,Q08CZ0,Ubiquitin-protein ligase E3B (EC 6.3.2.-),Ubiquitin-protein ligase E3B (EC 6.3.2.-),GO:0004842,ubiquitin-protein ligase activity,PF00632;PF00612;,3.00E-44,CHOYP_LOC659339.2.2,,,,,,,UBE3B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp116895_c1_seq1,338,38.4615,0.96857991,5,12,,2.00E-12,P33267,Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Cytochrome P450-NAH-2) (Naphthalene dehydrogenase) (Naphthalene hydroxylase),Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Cytochrome P450-NAH-2) (Naphthalene dehydrogenase) (Naphthalene hydroxylase),GO:0005789; GO:0020037; GO:0005506; GO:0018931; GO:0016712; GO:0019825; GO:0009636,"endoplasmic reticulum membrane; heme binding; iron ion binding; naphthalene metabolic process; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; oxygen binding; response to toxic substance",PF00067;,,,,,,,,,CP2F2_MOUSE,Mus musculus (Mouse),epoxygenase P450 pathway [GO:0019373]; naphthalene metabolic process [GO:0018931]; response to toxic substance [GO:0009636]; trichloroethylene metabolic process [GO:0018979] comp116901_c1_seq1,594,46.1279,0.50732891,27,29,,2.00E-71,Q99698,Lysosomal-trafficking regulator (Beige homolog),Lysosomal-trafficking regulator (Beige homolog),GO:0002456; GO:0007596; GO:0005829; GO:0042742; GO:0042832; GO:0051607; GO:0032510; GO:0030595; GO:0007040; GO:0033364; GO:0032438; GO:0015630; GO:0007017; GO:0042267; GO:0002446; GO:0055091; GO:0006644; GO:0032816; GO:0042493; GO:0033299,T cell mediated immunity; blood coagulation; cytosol; defense response to bacterium; defense response to protozoan; defense response to virus; endosome to lysosome transport via multivesicular body sorting pathway; leukocyte chemotaxis; lysosome organization; mast cell secretory granule organization; melanosome organization; microtubule cytoskeleton; microtubule-based process; natural killer cell mediated cytotoxicity; neutrophil mediated immunity; phospholipid homeostasis; phospholipid metabolic process; positive regulation of natural killer cell activation; response to drug; secretion of lysosomal enzymes,PF02138;PF14844;PF00400;,2.00E-55,CHOYP_BRAFLDRAFT_126843.1.1,,,,,,,LYST_HUMAN,Homo sapiens (Human),defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031] comp116918_c0_seq1,1377,45.7516,0.30702561,78,8,,4.00E-124,Q3URV1,Protein broad-minded (TBC1 domain family member 32),Protein broad-minded (TBC1 domain family member 32),GO:0005097; GO:0005929; GO:0035083; GO:0005737; GO:0042733; GO:0002088; GO:0032851; GO:0061512; GO:0003406; GO:0060831,Rab GTPase activator activity; cilium; cilium axoneme assembly; cytoplasm; embryonic digit morphogenesis; lens development in camera-type eye; positive regulation of Rab GTPase activity; protein localization to cilium; retinal pigment epithelium development; smoothened signaling pathway involved in dorsal/ventral neural tube patterning,PF14961;,3.00E-49,CHOYP_BROMI.1.2,,,,,,,BROMI_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic digit morphogenesis [GO:0042733]; heart development [GO:0007507]; lens development in camera-type eye [GO:0002088]; neural tube development [GO:0021915]; protein localization to cilium [GO:0061512]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] comp116920_c0_seq1,879,36.8601,0.40243955,4623,3427,,1.00E-50,Q32P85,"Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic)","Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic)",GO:0005868; GO:0005874; GO:0003774; GO:0006810,cytoplasmic dynein complex; microtubule; motor activity; transport,PF03259;,3.00E-41,CHOYP_LOC100370139.4.4,5.00E-74,ruditapes_lrc13723,,,,,DLRB2_BOVIN,Bos taurus (Bovine),microtubule-based movement [GO:0007018]; transport [GO:0006810] comp116942_c0_seq1,262,42.3664,0.51569379,38,12,,2.00E-06,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp116946_c0_seq1,1779,40.4722,0.39095114,42,353,,2.00E-54,Q8VDL4,ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147),ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147),GO:0043843; GO:0005576; GO:0006096; GO:0046872,ADP-specific glucokinase activity; extracellular region; glycolysis; metal ion binding,PF04587;,6.00E-79,CHOYP_LOC100216148.1.1,,,,,,,ADPGK_MOUSE,Mus musculus (Mouse),glycolytic process [GO:0006096] comp116951_c0_seq2,304,38.8158,0,20,0,,,,,,,,,1.00E-15,CHOYP_contig_041837,,,,,,,,, comp116964_c0_seq1,576,46.0069,0.37039094,31,46,,4.00E-32,Q9H2M9,Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0006886; GO:0005886; GO:0046982,GTPase activator activity; cytoplasm; intracellular protein transport; plasma membrane; protein heterodimerization activity,PF14656;PF14655;,1.00E-12,CHOYP_RBGPR.1.1,,,,,,,RBGPR_HUMAN,Homo sapiens (Human),establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp116977_c0_seq1,897,44.2586,0.4802145,32,68,,6.00E-100,Q9H3F6,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10),BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10),GO:0031463; GO:0005737; GO:0005634; GO:0043161; GO:0051260; GO:0016567,Cul3-RING ubiquitin ligase complex; cytoplasm; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein homooligomerization; protein ubiquitination,PF02214;,3.00E-48,CHOYP_BACD3.1.1,5.00E-30,ruditapes_c7585,,,,,BACD3_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] comp116990_c0_seq1,557,42.0108,0.90099373,0,73,,2.00E-16,Q687X5,"Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9)","Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9)",GO:0000139; GO:0045444; GO:0016021; GO:0006811; GO:0055072; GO:0046872; GO:0016491; GO:0005886,Golgi membrane; fat cell differentiation; integral to membrane; ion transport; iron ion homeostasis; metal ion binding; oxidoreductase activity; plasma membrane,PF03807;PF01794;,,,,,,,,,STEA4_HUMAN,Homo sapiens (Human),copper ion import [GO:0015677]; fat cell differentiation [GO:0045444]; ferric iron import into cell [GO:0097461]; iron ion homeostasis [GO:0055072] comp116993_c1_seq1,923,47.3456,0.54626136,54,14,,2.00E-50,Q8TDY2,RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200),RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200),GO:0007254; GO:0070969; GO:0000045; GO:0007049; GO:0005829; GO:0007507; GO:0001889; GO:0043066; GO:0005634; GO:0045793; GO:0001934; GO:0034045; GO:0010506; GO:0006355; GO:0006351,"JNK cascade; ULK1-ATG13-FIP200 complex; autophagic vacuole assembly; cell cycle; cytosol; heart development; liver development; negative regulation of apoptotic process; nucleus; positive regulation of cell size; positive regulation of protein phosphorylation; pre-autophagosomal structure membrane; regulation of autophagy; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10377;,,,,,,,,,RBCC1_HUMAN,Homo sapiens (Human),"autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell cycle [GO:0007049]; heart development [GO:0007507]; JNK cascade [GO:0007254]; liver development [GO:0001889]; macroautophagy [GO:0016236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell size [GO:0045793]; positive regulation of protein phosphorylation [GO:0001934]; regulation of autophagy [GO:0010506]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp116993_c4_seq1,583,47.5129,0.39807164,38,0,,,,,,,,,9.00E-65,CHOYP_RBCC1.1.2,,,,,,,,, comp116996_c0_seq1,379,40.8971,0.6329158,9,39,,8.00E-60,Q0KI50,"Dystrophin, isoform D (Protein detached)","Dystrophin, isoform D (Protein detached)",GO:0003779; GO:0005509; GO:0005737; GO:0005856; GO:0016010; GO:0030010; GO:0008586; GO:0007474; GO:0046716; GO:0007517; GO:0007274; GO:0046928; GO:0048172; GO:0042383; GO:0005198; GO:0045202; GO:0008270,actin binding; calcium ion binding; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; establishment of cell polarity; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; muscle cell cellular homeostasis; muscle organ development; neuromuscular synaptic transmission; regulation of neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity; sarcolemma; structural molecule activity; synapse; zinc ion binding,PF09068;PF09069;PF00569;,5.00E-28,CHOYP_DMDE.1.1,,,,,,,DMDD_DROME,Drosophila melanogaster (Fruit fly),establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172] comp116996_c1_seq1,390,43.0769,0.11089126,8,23,,,,,,,,,3.00E-62,CHOYP_DLP.1.1,,,,,,,,, comp117016_c0_seq1,579,38.6874,0.55644554,30,8,,3.00E-06,Q9JJP6,Tumor protein 63 (p63) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L),Tumor protein 63 (p63) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L),GO:0005794; GO:0007219; GO:0001077; GO:0007569; GO:0003682; GO:0006338; GO:0060197; GO:0003684; GO:0007499; GO:0030326; GO:0010481; GO:0002064; GO:0001736; GO:0048807; GO:0031069; GO:0042771; GO:0030216; GO:0043616; GO:0046872; GO:0010259; GO:0043066; GO:0045617; GO:2000381; GO:0000122; GO:0051402; GO:0000790; GO:0005654; GO:0042475; GO:0030859; GO:0045747; GO:0002053; GO:0045669; GO:0036342; GO:0060513; GO:0051289; GO:0009954; GO:0043565; GO:0001501; GO:0048745; GO:0060529; GO:0048485; GO:0044212; GO:0060157,Golgi apparatus; Notch signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell aging; chromatin binding; chromatin remodeling; cloacal septation; damaged DNA binding; ectoderm and mesoderm interaction; embryonic limb morphogenesis; epidermal cell division; epithelial cell development; establishment of planar polarity; female genitalia morphogenesis; hair follicle morphogenesis; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; keratinocyte differentiation; keratinocyte proliferation; metal ion binding; multicellular organismal aging; negative regulation of apoptotic process; negative regulation of keratinocyte differentiation; negative regulation of mesoderm development; negative regulation of transcription from RNA polymerase II promoter; neuron apoptotic process; nuclear chromatin; nucleoplasm; odontogenesis of dentin-containing tooth; polarized epithelial cell differentiation; positive regulation of Notch signaling pathway; positive regulation of mesenchymal cell proliferation; positive regulation of osteoblast differentiation; post-anal tail morphogenesis; prostatic bud formation; protein homotetramerization; proximal/distal pattern formation; sequence-specific DNA binding; skeletal system development; smooth muscle tissue development; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; sympathetic nervous system development; transcription regulatory region DNA binding; urinary bladder development,PF00870;PF07710;PF07647;,,,,,,,,,P63_RAT,Rattus norvegicus (Rat),"cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; ectoderm and mesoderm interaction [GO:0007499]; embryonic limb morphogenesis [GO:0030326]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G1 DNA damage checkpoint [GO:0031571]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of neuron apoptotic process [GO:0043523]; replicative cell aging [GO:0001302]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]; urinary bladder development [GO:0060157]" comp117018_c0_seq1,730,37.2603,1.22944024,822,3703,,,,,,,,,8.00E-16,CHOYP_contig_027023,7.00E-40,ruditapes_c3292,,,,,,, comp117019_c0_seq1,628,40.7643,0.94687564,33,4126,female>male,8.00E-22,Q53533,Streptavidin-V2 (SA V2),Streptavidin-V2 (SA V2),GO:0005576,extracellular region,PF01382;,,,,,,,,,SAV2_STRVL,Streptomyces violaceus (Streptomyces venezuelae), comp117027_c0_seq1,295,40.339,0.66893424,2,0,,5.00E-10,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp117045_c0_seq1,269,46.8401,1.09534982,2,12,,2.00E-08,Q9TU34,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0035091; GO:0051209; GO:0030658,"endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; phosphatidylinositol binding; release of sequestered calcium ion into cytosol; transport vesicle membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,7.00E-37,CHOYP_TRIADDRAFT_55241.1.1,,,,,,,ITPR1_BOVIN,Bos taurus (Bovine),intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209] comp117046_c0_seq2,565,41.4159,0.66549297,0,0,,,,,,,,,6.00E-54,CHOYP_LOC100878904.1.1,,,,,,,,, comp117046_c0_seq3,664,41.1145,0.57383368,5,11,,1.00E-66,Q8R4F0,Mucolipin-3,Mucolipin-3,GO:0042491; GO:0005737; GO:0016021; GO:0006811; GO:0007626; GO:0005886,auditory receptor cell differentiation; cytoplasm; integral to membrane; ion transport; locomotory behavior; plasma membrane,PF08016;,,,,,,,,,MCLN3_MOUSE,Mus musculus (Mouse),auditory receptor cell differentiation [GO:0042491]; ion transport [GO:0006811]; locomotory behavior [GO:0007626] comp117048_c0_seq1,420,41.4286,0.44521072,0,0,,3.00E-09,Q9H091,Zinc finger MYND domain-containing protein 15,Zinc finger MYND domain-containing protein 15,GO:0005737; GO:0046872; GO:0045892; GO:0005634; GO:0007286; GO:0006351,"cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; spermatid development; transcription, DNA-dependent",PF01753;,,,,,,,,,ZMY15_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]" comp117048_c1_seq1,328,44.2073,0.31477522,16,6,,4.00E-08,Q8C0R7,Zinc finger MYND domain-containing protein 15,Zinc finger MYND domain-containing protein 15,GO:0005737; GO:0042826; GO:0046872; GO:0045892; GO:0005634; GO:0007286; GO:0006351,"cytoplasm; histone deacetylase binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; spermatid development; transcription, DNA-dependent",PF01753;,,,,,,,,,ZMY15_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]" comp117049_c0_seq2,687,46.2882,0.68132448,7,0,,1.00E-114,Q06725,Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44),Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44),GO:0030522; GO:0004879; GO:0005634; GO:0043565; GO:0003707; GO:0008270,intracellular receptor signaling pathway; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,N2F1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"endothelial cell proliferation [GO:0001935]; transcription, DNA-templated [GO:0006351]; vasculature development [GO:0001944]" comp117049_c0_seq3,716,46.5084,0.67514256,4,0,,,,,,,,,4.00E-108,CHOYP_N2F1A.1.1,,,,,,,,, comp117049_c0_seq4,339,46.6077,0.87671996,2,0,,2.00E-32,P49117,Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4),Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4),GO:0030154; GO:0021549; GO:0051321; GO:0005634; GO:0048520; GO:0040019; GO:0043565; GO:0003700; GO:0007283; GO:0003707; GO:0006351; GO:0008270,"cell differentiation; cerebellum development; meiotic cell cycle; nucleus; positive regulation of behavior; positive regulation of embryonic development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; spermatogenesis; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,NR2C2_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; cerebellum development [GO:0021549]; meiotic cell cycle [GO:0051321]; mitophagy in response to mitochondrial depolarization [GO:0098779]; p38MAPK cascade [GO:0038066]; positive regulation of behavior [GO:0048520]; positive regulation of embryonic development [GO:0040019]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp11704_c0_seq1,423,46.8085,0.22754233,12,0,,3.00E-12,Q14393,Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand),Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand),GO:0035754; GO:0005796; GO:0032148; GO:0043277; GO:0060090; GO:0005509; GO:0007050; GO:0008283; GO:0031589; GO:0035690; GO:0071333; GO:0071363; GO:0035457; GO:0009267; GO:0071307; GO:0043027; GO:0097028; GO:0005788; GO:0007167; GO:0085029; GO:0005615; GO:0019064; GO:0097241; GO:0010934; GO:0070168; GO:2000669; GO:2000352; GO:2000270; GO:0032689; GO:0050711; GO:0032715; GO:1900165; GO:1900142; GO:0033159; GO:2000533; GO:0043433; GO:0045892; GO:0032720; GO:0010804; GO:0001764; GO:0031100; GO:0017187; GO:0018105; GO:0001786; GO:0070527; GO:0031093; GO:0002576; GO:0070374; GO:0032008; GO:0001961; GO:2000510; GO:0048146; GO:0010628; GO:0003104; GO:0032825; GO:0033138; GO:0050766; GO:0046827; GO:0051897; GO:0043687; GO:0043491; GO:0072661; GO:0030296; GO:0006508; GO:0048018; GO:0040008; GO:0019079; GO:0046813; GO:0005245,"B cell chemotaxis; Golgi lumen; activation of protein kinase B activity; apoptotic cell clearance; binding, bridging; calcium ion binding; cell cycle arrest; cell proliferation; cell-substrate adhesion; cellular response to drug; cellular response to glucose stimulus; cellular response to growth factor stimulus; cellular response to interferon-alpha; cellular response to starvation; cellular response to vitamin K; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; dendritic cell differentiation; endoplasmic reticulum lumen; enzyme linked receptor protein signaling pathway; extracellular matrix assembly; extracellular space; fusion of virus membrane with host plasma membrane; hematopoietic stem cell migration to bone marrow; macrophage cytokine production; negative regulation of biomineral tissue development; negative regulation of dendritic cell apoptotic process; negative regulation of endothelial cell apoptotic process; negative regulation of fibroblast apoptotic process; negative regulation of interferon-gamma production; negative regulation of interleukin-1 secretion; negative regulation of interleukin-6 production; negative regulation of interleukin-6 secretion; negative regulation of oligodendrocyte apoptotic process; negative regulation of protein import into nucleus, translocation; negative regulation of renal albumin absorption; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor production; negative regulation of tumor necrosis factor-mediated signaling pathway; neuron migration; organ regeneration; peptidyl-glutamic acid carboxylation; peptidyl-serine phosphorylation; phosphatidylserine binding; platelet aggregation; platelet alpha granule lumen; platelet degranulation; positive regulation of ERK1 and ERK2 cascade; positive regulation of TOR signaling cascade; positive regulation of cytokine-mediated signaling pathway; positive regulation of dendritic cell chemotaxis; positive regulation of fibroblast proliferation; positive regulation of gene expression; positive regulation of glomerular filtration; positive regulation of natural killer cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of phagocytosis; positive regulation of protein export from nucleus; positive regulation of protein kinase B signaling cascade; post-translational protein modification; protein kinase B signaling cascade; protein targeting to plasma membrane; protein tyrosine kinase activator activity; proteolysis; receptor agonist activity; regulation of growth; viral genome replication; virion attachment, binding of host cell surface receptor; voltage-gated calcium channel activity",PF07645;PF00594;PF00054;PF02210;,,,,,,,,,GAS6_HUMAN,Homo sapiens (Human),"activation of protein kinase B activity [GO:0032148]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; enzyme linked receptor protein signaling pathway [GO:0007167]; ER to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; organ regeneration [GO:0031100]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein targeting to plasma membrane [GO:0072661]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal peptide processing [GO:0006465]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]" comp117053_c0_seq2,613,35.8891,0.31382654,12,43,,,,,,,,,,,2.00E-13,ruditapes_c5291,,,,,,, comp117069_c1_seq1,383,40.47,0.38400262,11,0,,3.00E-57,F1M386,Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),GO:0005096; GO:0030165; GO:0017034; GO:0032486; GO:0050699; GO:0071880; GO:0031697; GO:0001568; GO:0031547; GO:0030552; GO:0019933; GO:0005911; GO:0071320; GO:0071321; GO:0061028; GO:0021884; GO:0005770; GO:0008285; GO:0050774; GO:0048022; GO:0038180; GO:0001764; GO:0043005; GO:0031175; GO:0043025; GO:0007218; GO:0048471; GO:0005886; GO:0070374; GO:0032854; GO:2000481; GO:0043950; GO:2000670; GO:2001224; GO:0010976; GO:0032092; GO:2001214; GO:0043234; GO:1901888; GO:0048167; GO:0045202; GO:0021591,GTPase activator activity; PDZ domain binding; Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; WW domain binding; adenylate cyclase-activating adrenergic receptor signaling pathway; beta-1 adrenergic receptor binding; blood vessel development; brain-derived neurotrophic factor receptor signaling pathway; cAMP binding; cAMP-mediated signaling; cell-cell junction; cellular response to cAMP; cellular response to cGMP; establishment of endothelial barrier; forebrain neuron development; late endosome; negative regulation of cell proliferation; negative regulation of dendrite morphogenesis; negative regulation of melanin biosynthetic process; nerve growth factor signaling pathway; neuron migration; neuron projection; neuron projection development; neuronal cell body; neuropeptide signaling pathway; perinuclear region of cytoplasm; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of Rap GTPase activity; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cAMP-mediated signaling; positive regulation of dendritic cell apoptotic process; positive regulation of neuron migration; positive regulation of neuron projection development; positive regulation of protein binding; positive regulation of vasculogenesis; protein complex; regulation of cell junction assembly; regulation of synaptic plasticity; synapse; ventricular system development,PF00595;PF00788;PF00617;PF00618;,7.00E-26,CHOYP_BRAFLDRAFT_131151.4.4,,,,,,,RPGF2_RAT,Rattus norvegicus (Rat),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591] comp117072_c0_seq1,625,46.72,0.35915181,25,29,,4.00E-19,Q6TNR1,Rhophilin-2 (GTP-Rho-binding protein 2),Rhophilin-2 (GTP-Rho-binding protein 2),GO:0005737; GO:0007165,cytoplasm; signal transduction,PF03097;PF02185;,,,,,,,,,RHPN2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),signal transduction [GO:0007165] comp117075_c0_seq2,1105,38.6425,0.49072717,43,204,,5.00E-54,Q9DCM0,"Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Ethylmalonic encephalopathy protein 1 homolog) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1)","Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Ethylmalonic encephalopathy protein 1 homolog) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1)",GO:0006749; GO:0070813; GO:0016787; GO:0005506; GO:0005759; GO:0005739; GO:0005634; GO:0050313,glutathione metabolic process; hydrogen sulfide metabolic process; hydrolase activity; iron ion binding; mitochondrial matrix; mitochondrion; nucleus; sulfur dioxygenase activity,PF00753;,1.00E-46,CHOYP_DPSE_GA30464.1.1,,,,,,,ETHE1_MOUSE,Mus musculus (Mouse),glutathione metabolic process [GO:0006749]; hydrogen sulfide metabolic process [GO:0070813] comp117080_c0_seq1,662,33.2326,0.90666874,21,99,,2.00E-16,Q9EQC0,Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1) (GST-1) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST),Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1) (GST-1) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST),GO:0000139; GO:0006012; GO:0006954; GO:0016021; GO:0042339; GO:0045130,Golgi membrane; galactose metabolic process; inflammatory response; integral to membrane; keratan sulfate metabolic process; keratan sulfotransferase activity,PF00685;,,,,,,,,,CHST1_MOUSE,Mus musculus (Mouse),galactose metabolic process [GO:0006012]; inflammatory response [GO:0006954]; keratan sulfate metabolic process [GO:0042339]; sulfur compound metabolic process [GO:0006790] comp117085_c0_seq1,241,43.9834,0.35073068,14,0,,,,,,,,,7.00E-11,CHOYP_BRAFLDRAFT_258021.1.1,,,,,,,,, comp117085_c2_seq1,607,48.4349,0.59654793,19,4,,1.00E-47,P56730,Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12),GO:0030424; GO:0031410; GO:0030425; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252; GO:0008236; GO:0043083; GO:0043195; GO:0031638,axon; cytoplasmic vesicle; dendrite; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity; serine-type peptidase activity; synaptic cleft; terminal bouton; zymogen activation,PF00051;PF00530;PF00089;,3.00E-13,CHOYP_DMBT1.9.34,,,,,,,NETR_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; zymogen activation [GO:0031638] comp117085_c3_seq1,580,50.5172,0.67342999,18,0,,2.00E-43,Q2VLH6,Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],GO:0006953; GO:0005576; GO:0016021; GO:0005886; GO:0005044,acute-phase response; extracellular region; integral to membrane; plasma membrane; scavenger receptor activity,PF00530;,,,,,,,,,C163A_MOUSE,Mus musculus (Mouse),acute-phase response [GO:0006953] comp117112_c0_seq1,1520,35.0658,0.36828103,63,158,,1.00E-07,Q17RP2,Tigger transposable element-derived protein 6,Tigger transposable element-derived protein 6,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD6_HUMAN,Homo sapiens (Human), comp117114_c0_seq1,433,47.1132,0.50367773,7,35,,2.00E-42,Q6P6V1,Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11),Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11),GO:0000139; GO:0016021; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,,,,,,,,,GLT11_RAT,Rattus norvegicus (Rat),cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593] comp117122_c0_seq3,2196,43.7614,0.49186577,36,0,,3.00E-10,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,3.00E-27,CHOYP_TVAG_291510.3.9,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp117122_c0_seq4,1088,41.8199,0.39050953,2,0,,4.00E-09,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,1.00E-27,CHOYP_TVAG_291510.3.9,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp117126_c0_seq1,596,43.7919,0.77213621,0,6,,3.00E-56,Q9GUM2,"Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)","Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)",GO:0033207; GO:0075015; GO:0016021; GO:0046872; GO:0045747; GO:0006486; GO:0009636,"beta-1,4-N-acetylgalactosaminyltransferase activity; formation of infection structure on or near host; integral to membrane; metal ion binding; positive regulation of Notch signaling pathway; protein glycosylation; response to toxic substance",PF02709;PF13733;,,,,,,,,,BRE4_CAEEL,Caenorhabditis elegans,formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636] comp117128_c1_seq1,411,47.6886,0.72935973,1,56,,4.00E-29,Q8IYS1,Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),GO:0016787,hydrolase activity,PF07687;PF01546;,2.00E-27,CHOYP_PM20D2.1.1,,,,,,,P20D2_HUMAN,Homo sapiens (Human),proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268] comp117144_c0_seq1,460,44.3478,0.80561647,18,23,,6.00E-13,Q641S4,Selenoprotein K (SelK),Selenoprotein K (SelK),,,PF10961;,2.00E-21,CHOYP_LOC580102.3.3,,,,,,,SELK_XENLA,Xenopus laevis (African clawed frog),calcium ion transport [GO:0006816] comp117151_c0_seq1,531,43.3145,0.44333491,4,77,,2.00E-11,P34616,Cadherin-3,Cadherin-3,GO:0005509; GO:0030054; GO:0005737; GO:0007156; GO:0016021; GO:0016331; GO:0005886; GO:0005198; GO:0045138,calcium ion binding; cell junction; cytoplasm; homophilic cell adhesion; integral to membrane; morphogenesis of embryonic epithelium; plasma membrane; structural molecule activity; tail tip morphogenesis,PF00028;PF00054;,,,,,,,,,CADH3_CAEEL,Caenorhabditis elegans,homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of embryonic epithelium [GO:0016331]; nematode male tail tip morphogenesis [GO:0045138] comp117151_c1_seq1,715,40.1399,0.27843725,3,87,,3.00E-09,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp117154_c0_seq1,360,43.3333,0.72164475,2,28,,8.00E-33,Q8NHQ8,Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1),Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1),GO:0007165,signal transduction,PF00788;,,,,,,,,,RASF8_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp117156_c0_seq1,329,34.6505,0.73357299,15,16,,1.00E-11,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp117159_c0_seq3,1356,39.7493,0.44937519,3,18,,4.00E-12,Q02525,Zinc finger protein 39 (Zfp-39) (CtFIN33),Zinc finger protein 39 (Zfp-39) (CtFIN33),GO:0003677; GO:0030154; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0007283; GO:0006351,"DNA binding; cell differentiation; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZFP39_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp117179_c0_seq2,596,46.1409,0.47506765,13,24,,5.00E-37,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp117181_c0_seq1,493,44.4219,0.37361498,11,8,,3.00E-69,E1BNQ4,ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein),ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase),GO:0005524; GO:0047453; GO:0005739,ATP binding; ATP-dependent NAD(P)H-hydrate dehydratase activity; mitochondrion,PF01256;,,,,,,,,,NNRD_BOVIN,Bos taurus (Bovine),nicotinamide nucleotide metabolic process [GO:0046496] comp117183_c1_seq2,654,40.5199,0.41209202,4,49,,,,,,,,,7.00E-16,CHOYP_LOC100632453.1.1,,,,,,,,, comp117186_c0_seq2,779,45.5712,0.89501008,6,73,,4.00E-48,A2RU49,Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1),Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1),GO:0005737; GO:0047992,cytoplasm; hydroxylysine kinase activity,PF01636;,,,,,,,,,AGPD1_HUMAN,Homo sapiens (Human),lysine catabolic process [GO:0006554] comp117194_c0_seq1,692,40.7514,0.56178868,13,61,,2.00E-50,B0BML7,Sepiapterin reductase (SPR) (EC 1.1.1.153),Sepiapterin reductase (SPR) (EC 1.1.1.153),GO:0005737; GO:0004757; GO:0006729,cytoplasm; sepiapterin reductase activity; tetrahydrobiopterin biosynthetic process,PF00106;,1.00E-25,CHOYP_SPR.1.3,,,,,,,SPRE_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),tetrahydrobiopterin biosynthetic process [GO:0006729] comp117195_c1_seq1,1543,42.1905,0.49708376,8,9,,,,,,,,,2.00E-26,CHOYP_LOC100367317.1.1,,,,,,,,, comp117208_c0_seq4,231,37.6623,0.73574317,6,5,,,,,,,,,,,8.00E-14,ruditapes_c3092,,,,,,, comp117222_c0_seq1,1030,43.5922,0.52608532,46,49,,1.00E-84,Q6GQ76,Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),GO:0006370; GO:0097309; GO:0004483; GO:0003676; GO:0005634,7-methylguanosine mRNA capping; cap1 mRNA methylation; mRNA (nucleoside-2'-O-)-methyltransferase activity; nucleic acid binding; nucleus,PF01728;PF01585;,,,,,,,,,MTR1_XENLA,Xenopus laevis (African clawed frog),7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009] comp117223_c0_seq1,841,34.3639,0.36612285,216,689,,4.00E-17,Q6J3Q7,Cytochrome c oxidase copper chaperone,Cytochrome c oxidase copper chaperone,GO:0016531; GO:0006825; GO:0005758,copper chaperone activity; copper ion transport; mitochondrial intermembrane space,PF05051;,,,,,,,,,COX17_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617] comp117228_c0_seq2,525,37.7143,0.81173134,8,35,,2.00E-20,Q924Z4,Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3),Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3),GO:0046513; GO:0005789; GO:0016021; GO:0031965; GO:0043565; GO:0003700; GO:0050291,ceramide biosynthetic process; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sphingosine N-acyltransferase activity,PF00046;PF03798;,,,,,,,,,CERS2_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148] comp117230_c0_seq1,1504,41.6223,0.87529118,13,146,,4.00E-15,Q7W977,Ectoine hydroxylase (EC 1.17.-.-),Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase),GO:0016725,"oxidoreductase activity, acting on CH or CH2 groups",PF05721;,,,,,,,,,ECTD_BORPA,Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253),ectoine catabolic process [GO:0042400] comp117230_c0_seq2,1422,41.4909,0.89559485,0,9,,3.00E-12,Q93RV9,Ectoine hydroxylase (EC 1.17.-.-),Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase),GO:0016725,"oxidoreductase activity, acting on CH or CH2 groups",PF05721;,8.00E-51,CHOYP_LOC100641267.2.2,2.00E-68,ruditapes_c26815,,,,,ECTD_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),ectoine catabolic process [GO:0042400] comp117233_c1_seq1,614,40.7166,0.51220586,22,3,,9.00E-08,Q80U62,Run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon),Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon),GO:0005794; GO:0006914; GO:0005769; GO:0006897; GO:0005770; GO:0005764; GO:0010507; GO:0045806,Golgi apparatus; autophagy; early endosome; endocytosis; late endosome; lysosome; negative regulation of autophagy; negative regulation of endocytosis,PF02759;PF13901;,,,,,,,,,RUBIC_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; endocytosis [GO:0006897]; immune system process [GO:0002376]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553] comp117233_c3_seq1,218,53.211,0.65413563,3,0,,,,,,,,,8.00E-16,CHOYP_LOC100377422.2.2,,,,,,,,, comp117240_c0_seq2,1132,46.3781,0.67444445,5,169,,2.00E-96,Q9Y345,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015375; GO:0016021; GO:0005328; GO:0005886; GO:0007268,glycine:sodium symporter activity; integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane; synaptic transmission,PF00209;,8.00E-88,CHOYP_SC6A5.3.7,,,,,,,SC6A5_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp117240_c1_seq1,442,45.7014,0.92733728,0,52,,7.00E-10,O07577,Uncharacterized sodium-dependent transporter YhdH,Uncharacterized sodium-dependent transporter YhdH,GO:0016021; GO:0005328; GO:0005886,integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,8.00E-26,CHOYP_SC6A5.1.7,,,,,,,YHDH_BACSU,Bacillus subtilis (strain 168), comp117241_c0_seq1,1032,42.7326,0.65939853,32,85,,4.00E-25,Q8CCI5,RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor),RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor),GO:0003677; GO:0006915; GO:0005737; GO:0000122; GO:0005654; GO:0003714; GO:0006351; GO:0008270,"DNA binding; apoptotic process; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; transcription corepressor activity; transcription, DNA-dependent; zinc ion binding",PF00641;,6.00E-26,CHOYP_YAF2.1.1,,,,,,,RYBP_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; histone H2A monoubiquitination [GO:0035518]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp117243_c1_seq2,507,38.4615,0.97318386,4,36,,1.00E-22,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp117243_c1_seq3,353,41.0765,0.5400501,4,17,,1.00E-15,Q9Y2F9,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,,,,,,,,,BTBD3_HUMAN,Homo sapiens (Human),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp117244_c1_seq1,816,44.3627,0.79841317,27,77,,1.00E-19,P0C548,Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase),Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase),GO:0016021; GO:0005811; GO:0010891; GO:0005886; GO:0010898; GO:0019433; GO:0004806,integral to membrane; lipid particle; negative regulation of sequestering of triglyceride; plasma membrane; positive regulation of triglyceride catabolic process; triglyceride catabolic process; triglyceride lipase activity,PF01734;,,,,,,,,,PLPL2_RAT,Rattus norvegicus (Rat),lipid homeostasis [GO:0055088]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] comp117245_c0_seq1,567,44.2681,0.4829947,58,80,,8.00E-09,Q64127,Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase Trim24) (Tripartite motif-containing protein 24),Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase Trim24) (Tripartite motif-containing protein 24),GO:0055074; GO:0071391; GO:0003682; GO:0005737; GO:0034056; GO:0070577; GO:0016922; GO:0008285; GO:0045892; GO:0005719; GO:0005726; GO:0045893; GO:0046777; GO:0030163; GO:0004672; GO:0042981; GO:0031647; GO:1901796; GO:0070562; GO:0043565; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"calcium ion homeostasis; cellular response to estrogen stimulus; chromatin binding; cytoplasm; estrogen response element binding; histone acetyl-lysine binding; ligand-dependent nuclear receptor binding; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nuclear euchromatin; perichromatin fibrils; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein catabolic process; protein kinase activity; regulation of apoptotic process; regulation of protein stability; regulation of signal transduction by p53 class mediator; regulation of vitamin D receptor signaling pathway; sequence-specific DNA binding; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TIF1A_MOUSE,Mus musculus (Mouse),"calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription, DNA-templated [GO:0006351]" comp117265_c0_seq1,716,45.9497,0.53253223,31,9,,9.00E-79,B2RYF1,Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68),Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68),GO:0010923; GO:0019902; GO:0004864,negative regulation of phosphatase activity; phosphatase binding; protein phosphatase inhibitor activity,PF13516;,8.00E-73,CHOYP_PPR37.1.1,,,,,,,PPR37_RAT,Rattus norvegicus (Rat),negative regulation of phosphatase activity [GO:0010923] comp117268_c0_seq1,326,47.546,0.49017783,0,0,,6.00E-09,Q9UMZ2,Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin),Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin),GO:0030121; GO:0005509; GO:0006897; GO:0006886,AP-1 adaptor complex; calcium ion binding; endocytosis; intracellular protein transport,,,,,,,,,,SYNRG_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] comp117281_c0_seq1,777,39.1248,0.67923982,15,84,,,,,,,,,2.00E-11,CHOYP_NAEGRDRAFT_59420.1.2,,,,,,,,, comp117284_c0_seq1,1149,43.0809,0.60130765,38,138,,2.00E-65,Q28DG7,Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2),Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2),GO:0005737; GO:0016567,cytoplasm; protein ubiquitination,PF00627;,4.00E-22,CHOYP_UBAC1.1.1,,,,,,,UBAC1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination [GO:0016567] comp117286_c0_seq1,699,48.2117,0.49978683,28,30,,1.00E-40,Q7ZUV7,Protein EMSY,BRCA2-interacting transcriptional repressor EMSY,GO:0006281; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA repair; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03735;,2.00E-43,CHOYP_RGD1310712.1.1,,,,,,,EMSY_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"chromatin modification [GO:0016568]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117298_c0_seq1,348,40.8046,0.35181742,3,0,,3.00E-12,Q4V7G1,Src kinase-associated phosphoprotein 1 (SKAP55 adapter protein) (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55),Src kinase-associated phosphoprotein 1 (SKAP55 adapter protein) (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55),GO:0050852; GO:0003823; GO:0005737; GO:0005634; GO:0005543; GO:0005886; GO:0045944,T cell receptor signaling pathway; antigen binding; cytoplasm; nucleus; phospholipid binding; plasma membrane; positive regulation of transcription from RNA polymerase II promoter,PF00169;PF00018;,,,,,,,,,SKAP1_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; immune response-activating signal transduction [GO:0002757]; positive regulation of cell adhesion [GO:0045785]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852] comp117298_c0_seq2,475,39.3684,0.22175733,3,0,,5.00E-12,Q5FVW6,Src kinase-associated phosphoprotein 2,Src kinase-associated phosphoprotein 2,GO:0042113; GO:0005737; GO:0005543,B cell activation; cytoplasm; phospholipid binding,PF00169;PF00018;,,,,,,,,,SKAP2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),B cell activation [GO:0042113]; immune response-activating signal transduction [GO:0002757] comp117305_c0_seq1,543,38.3057,0.70473081,20,729,,1.00E-27,P55260,Annexin A4 (36 kDa zymogen granule membrane-associated protein) (ZAP36) (Annexin IV) (Annexin-4) (Lipocortin IV),Annexin A4 (36 kDa zymogen granule membrane-associated protein) (ZAP36) (Annexin IV) (Annexin-4) (Lipocortin IV),GO:0005509; GO:0005544; GO:0006887,calcium ion binding; calcium-dependent phospholipid binding; exocytosis,PF00191;,,,4.00E-29,ruditapes_c7392,,,,,ANXA4_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887] comp117327_c0_seq1,333,42.6426,0.46389307,0,5,,4.00E-17,P10398,Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks),Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks),GO:0005524; GO:0004709; GO:0005829; GO:0046872; GO:0005739; GO:0043066; GO:0033138; GO:0004674; GO:0032006; GO:0032434,ATP binding; MAP kinase kinase kinase activity; cytosol; metal ion binding; mitochondrion; negative regulation of apoptotic process; positive regulation of peptidyl-serine phosphorylation; protein serine/threonine kinase activity; regulation of TOR signaling cascade; regulation of proteasomal ubiquitin-dependent protein catabolic process,PF00130;PF07714;PF02196;,,,,,,,,,ARAF_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006] comp117327_c0_seq2,399,42.6065,0.27697169,1,8,,2.00E-15,Q5R5M7,RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1),RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1),GO:0005524; GO:0006915; GO:0005737; GO:0007010; GO:0035556; GO:0046872; GO:0005739; GO:0043066; GO:0008285; GO:0031333; GO:0048011; GO:0005634; GO:0005886; GO:0033138; GO:0004674; GO:0031143; GO:0005057,ATP binding; apoptotic process; cytoplasm; cytoskeleton organization; intracellular signal transduction; metal ion binding; mitochondrion; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of protein complex assembly; neurotrophin TRK receptor signaling pathway; nucleus; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein serine/threonine kinase activity; pseudopodium; receptor signaling protein activity,PF00130;PF07714;PF02196;,,,,,,,,,RAF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),activation of MAPKK activity [GO:0000186]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular signal transduction [GO:0035556]; negative regulation of cell proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to muscle stretch [GO:0035994]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878] comp117327_c0_seq3,337,43.0267,0.38628912,0,3,,3.00E-19,Q04982,Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil),Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil),GO:0005524; GO:0005509; GO:0071277; GO:0005737; GO:0035556; GO:0043066; GO:0005634; GO:0005886; GO:0070374; GO:0010628; GO:0033138; GO:0004674; GO:0005057; GO:0070849,ATP binding; calcium ion binding; cellular response to calcium ion; cytoplasm; intracellular signal transduction; negative regulation of apoptotic process; nucleus; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of gene expression; positive regulation of peptidyl-serine phosphorylation; protein serine/threonine kinase activity; receptor signaling protein activity; response to epidermal growth factor stimulus,PF00130;PF07714;PF02196;,,,,,,,,,BRAF_CHICK,Gallus gallus (Chicken),"CD4-positive, alpha-beta T cell differentiation [GO:0043367]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; establishment of protein localization to membrane [GO:0090150]; face development [GO:0060324]; glucose transport [GO:0015758]; head morphogenesis [GO:0060323]; intracellular signal transduction [GO:0035556]; long-term synaptic potentiation [GO:0060291]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of axonogenesis [GO:0050772]; positive regulation of axon regeneration [GO:0048680]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive T cell selection [GO:0043368]; regulation of cell proliferation [GO:0042127]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; visual learning [GO:0008542]" comp117330_c0_seq1,736,44.2935,0.33795775,0,3,,2.00E-32,Q96L93,Kinesin-like protein KIF16B (Sorting nexin-23),Kinesin-like protein KIF16B (Sorting nexin-23),GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,2.00E-23,CHOYP_KI16B.1.3,,,,,,,KI16B_HUMAN,Homo sapiens (Human),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp117330_c0_seq2,424,46.4623,0.52729822,2,0,,1.00E-08,Q9NGQ2,Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),GO:0005524; GO:0030659; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005543; GO:0006810,ATP binding; cytoplasmic vesicle membrane; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; phospholipid binding; transport,PF00225;PF16183;PF00169;,,,,,,,,,KIF1_DICDI,Dictyostelium discoideum (Slime mold),plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496] comp117330_c0_seq3,763,44.1678,0.32728887,3,0,,2.00E-31,Q96L93,Kinesin-like protein KIF16B (Sorting nexin-23),Kinesin-like protein KIF16B (Sorting nexin-23),GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,,,,,,,,,KI16B_HUMAN,Homo sapiens (Human),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp117331_c0_seq1,542,41.8819,0.55269527,20,72,,1.00E-59,Q92504,"Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)","Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)",GO:0005794; GO:0005789; GO:0016021; GO:0046873; GO:0055085; GO:0006829,Golgi apparatus; endoplasmic reticulum membrane; integral to membrane; metal ion transmembrane transporter activity; transmembrane transport; zinc ion transport,PF02535;,5.00E-93,CHOYP_NEMVEDRAFT_V1G241132.1.1,,,,,,,S39A7_HUMAN,Homo sapiens (Human),cellular zinc ion homeostasis [GO:0006882]; zinc II ion transmembrane transport [GO:0071577] comp117340_c1_seq1,629,45.31,0.68323154,13,36,,3.00E-30,Q96I27,Zinc finger protein 625,Zinc finger protein 625,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN625_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117345_c0_seq2,780,43.5897,0.78370371,7,24,,7.00E-98,A5PLL7,Transmembrane protein 189,Transmembrane protein 189,GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF10520;,5.00E-63,CHOYP_AAEL_AAEL001208.1.1,,,,,,,TM189_HUMAN,Homo sapiens (Human), comp117346_c2_seq1,672,43.4524,0.56873365,34,23,,1.00E-55,Q8BWZ3,"N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)","N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)",GO:0005737,cytoplasm,PF09797;,1.00E-44,CHOYP_NAA25.1.1,,,,,,,NAA25_MOUSE,Mus musculus (Mouse),N-terminal peptidyl-methionine acetylation [GO:0017196] comp117349_c0_seq2,282,47.1631,0.52774556,1,12,,1.00E-14,O62675,Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)],Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)],GO:0006935; GO:0005737; GO:0005615; GO:0005634; GO:0006355; GO:0006351,"chemotaxis; cytoplasm; extracellular space; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00595;,,,,,,,,,IL16_MACMU,Macaca mulatta (Rhesus macaque),"chemotaxis [GO:0006935]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117351_c2_seq1,940,43.617,0.42593435,20,71,,3.00E-33,Q9H2G9,Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor),Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor),GO:0003677; GO:0005796; GO:0000139; GO:0007030; GO:0043001; GO:0008283; GO:0000278; GO:0005634; GO:0001558; GO:0006357; GO:0003700,DNA binding; Golgi lumen; Golgi membrane; Golgi organization; Golgi to plasma membrane protein transport; cell proliferation; mitotic cell cycle; nucleus; regulation of cell growth; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity,PF08227;,3.00E-29,CHOYP_BLZF1.1.1,,,,,,,GO45_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; Golgi organization [GO:0007030]; Golgi to plasma membrane protein transport [GO:0043001]; regulation of cell growth [GO:0001558]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp117354_c0_seq1,1843,39.8264,0.6147367,80,123,,3.00E-141,Q9H999,Pantothenate kinase 3 (hPanK3) (EC 2.7.1.33) (Pantothenic acid kinase 3),Pantothenate kinase 3 (hPanK3) (EC 2.7.1.33) (Pantothenic acid kinase 3),GO:0005524; GO:0015937; GO:0005737; GO:0004594,ATP binding; coenzyme A biosynthetic process; cytoplasm; pantothenate kinase activity,PF03630;,2.00E-117,CHOYP_PANK3.1.1,,,,,,,PANK3_HUMAN,Homo sapiens (Human),coenzyme A biosynthetic process [GO:0015937] comp117365_c3_seq1,320,60.3125,0.87897901,4,25,,8.00E-26,O05916,Divalent metal cation transporter MntH (Mramp),,GO:0016021; GO:0034755; GO:0071421; GO:0046872; GO:0005886; GO:0015293; GO:0071578,integral to membrane; iron ion transmembrane transport; manganese ion transmembrane transport; metal ion binding; plasma membrane; symporter activity; zinc ion transmembrane import,,,,,,,,,,MNTH_MYCTU,, comp117372_c1_seq1,2063,47.3097,0.41239998,46,49,,0,Q5TYW4,Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),GO:0009790; GO:0000184,"embryo development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",PF15492;PF08314;,,,,,,,,,NBAS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp117372_c2_seq1,736,44.0217,0.50556496,28,12,,4.00E-37,A2RRP1,Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein),Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein),GO:0005737,cytoplasm,PF15492;PF08314;,,,,,,,,,NBAS_HUMAN,Homo sapiens (Human),"negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp117377_c0_seq1,1301,36.9716,0.46471812,233,1117,,2.00E-15,Q4G078,mTERF domain-containing protein 2 (Mitochondrial transcription termination factor 4) (MTERF4),"Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (MTERF4) (mTERF domain-containing protein 2)",GO:0043010; GO:0007507; GO:0005762; GO:0006626; GO:0019843; GO:0006364; GO:0042255; GO:0006390,camera-type eye development; heart development; mitochondrial large ribosomal subunit; protein targeting to mitochondrion; rRNA binding; rRNA processing; ribosome assembly; transcription from mitochondrial promoter,PF02536;,,,,,,,,,MTER2_RAT,Rattus norvegicus (Rat),"camera-type eye development [GO:0043010]; heart development [GO:0007507]; protein targeting to mitochondrion [GO:0006626]; regulation of transcription, DNA-templated [GO:0006355]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]; transcription from mitochondrial promoter [GO:0006390]" comp117378_c0_seq1,882,44.1043,0.39739025,0,2,,2.00E-23,Q8CHH5,GLTSCR1-like protein,GLTSCR1-like protein,,,PF15249;,,,,,,,,,K0240_MOUSE,Mus musculus (Mouse), comp117378_c0_seq2,2670,44.5318,0.43972326,113,114,,1.00E-14,Q9NZM4,Glioma tumor suppressor candidate region gene 1 protein,Glioma tumor suppressor candidate region gene 1 protein,,,PF15249;,,,,,,,,,GSCR1_HUMAN,Homo sapiens (Human), comp117383_c0_seq1,987,42.3506,0.62186231,46,42,,6.00E-09,A0MZ67,Shootin-1,Shootin-1 (Shootin1),GO:0030424; GO:0007409; GO:0005829,axon; axonogenesis; cytosol,,,,,,,,,,SHOT1_RAT,Rattus norvegicus (Rat),"actin filament bundle retrograde transport [GO:0061573]; axonogenesis [GO:0007409]; Cdc42 protein signal transduction [GO:0032488]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; endoplasmic reticulum polarization [GO:0061163]; netrin-activated signaling pathway [GO:0038007]; positive regulation of axon extension [GO:0045773]; positive regulation of neuron migration [GO:2001224]; Ras protein signal transduction [GO:0007265]; regulation of establishment of cell polarity [GO:2000114]; substrate-dependent cell migration, cell extension [GO:0006930]" comp117390_c0_seq1,450,45.1111,0.61540265,0,0,,3.00E-15,O74304,MAP kinase kinase kinase win1 (EC 2.7.11.25),MAP kinase kinase kinase win1 (EC 2.7.11.25),GO:0005524; GO:0004709; GO:0051519; GO:0007346; GO:0051403,ATP binding; MAP kinase kinase kinase activity; activation of bipolar cell growth; regulation of mitotic cell cycle; stress-activated MAPK cascade,PF00069;,,,,,,,,,WIN1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),activation of MAPKK activity involved in osmosensory signaling pathway [GO:0000168]; MAPK cascade involved in osmosensory signaling pathway [GO:0000161]; stress-activated MAPK cascade [GO:0051403]; stress-activated protein kinase signaling cascade [GO:0031098] comp117390_c0_seq2,473,46.3002,0.55858836,1,3,,8.00E-85,Q29502,Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (p21-activated kinase 2) (PAK-2) (p21-activated protein kinase I) (PAKI) [Cleaved into: PAK-2p27; PAK-2p34],Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (p21-activated kinase 2) (PAK-2) (p21-activated protein kinase I) (PAKI) [Cleaved into: PAK-2p27; PAK-2p34],GO:0005524; GO:0005829; GO:0097194; GO:0016020; GO:0043066; GO:2001271; GO:0005654; GO:0018105; GO:0048471; GO:0043065; GO:2001238; GO:0046777; GO:0004674; GO:0030296,ATP binding; cytosol; execution phase of apoptosis; membrane; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; nucleoplasm; peptidyl-serine phosphorylation; perinuclear region of cytoplasm; positive regulation of apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activator activity,PF00786;PF00069;,9.00E-89,CHOYP_LOC100160077.1.1,6.00E-32,ruditapes_c16007,,,,,PAK2_RABIT,Oryctolagus cuniculus (Rabbit),cellular response to organic cyclic compound [GO:0071407]; dendritic spine development [GO:0060996]; execution phase of apoptosis [GO:0097194]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein autophosphorylation [GO:0046777] comp117402_c0_seq2,1248,38.8622,0.53443707,15,35,,3.00E-146,Q6DKC0,Erlin-2-B (Endoplasmic reticulum lipid raft-associated protein 2-B) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-B) (SPFH domain-containing protein 2-B),Erlin-2-B (Endoplasmic reticulum lipid raft-associated protein 2-B) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-B) (SPFH domain-containing protein 2-B),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF01145;,2.00E-121,CHOYP_ERL2B.1.1,,,,,,,ERL2B_XENLA,Xenopus laevis (African clawed frog),cholesterol metabolic process [GO:0008203]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433] comp117404_c0_seq1,512,36.5234,0.36076087,5,69,,3.00E-19,P24329,Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),GO:0008097; GO:0016226; GO:0005743; GO:0005759; GO:0005886; GO:0035928; GO:0004792,5S rRNA binding; iron-sulfur cluster assembly; mitochondrial inner membrane; mitochondrial matrix; plasma membrane; rRNA import into mitochondrion; thiosulfate sulfurtransferase activity,PF00581;,,,,,,,,,THTR_RAT,Rattus norvegicus (Rat),"epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" comp117423_c0_seq1,425,42.5882,0.37368628,12,22,,5.00E-15,Q99MV5,Putative helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1),RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog),GO:0005524; GO:0008283; GO:0005737; GO:0004386; GO:0007517; GO:0045786; GO:0007283,ATP binding; cell proliferation; cytoplasm; helicase activity; muscle organ development; negative regulation of cell cycle; spermatogenesis,,,,,,,,,,M10L1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp117429_c0_seq2,644,45.0311,1.16775735,4,21,,5.00E-11,Q9VZW5,FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor),FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor),GO:0002209; GO:0007204; GO:0005887; GO:0008345; GO:0008188,behavioral defense response; elevation of cytosolic calcium ion concentration; integral to plasma membrane; larval locomotory behavior; neuropeptide receptor activity,PF10324;,2.00E-35,CHOYP_CO6A5.1.6,,,,,,,FMAR_DROME,Drosophila melanogaster (Fruit fly),adult locomotory behavior [GO:0008344]; behavioral defense response [GO:0002209]; G-protein coupled receptor signaling pathway [GO:0007186]; larval locomotory behavior [GO:0008345]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration [GO:0007204] comp117434_c1_seq1,232,65.0862,1.18796159,0,21,,1.00E-32,Q6A9B0,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein MenD),2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein MenD),GO:0070204; GO:0009234; GO:0046872; GO:0030976,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; menaquinone biosynthetic process; metal ion binding; thiamine pyrophosphate binding,PF02775;PF02776;,,,,,,,,,MEND_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),menaquinone biosynthetic process [GO:0009234] comp117443_c0_seq1,689,40.7837,0.98320818,0,346,,2.00E-08,Q9ES30,Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),GO:0005581; GO:0005615; GO:0042593; GO:0042802; GO:0045721; GO:0070374; GO:0070165; GO:0050715; GO:0051897; GO:0051259,collagen; extracellular space; glucose homeostasis; identical protein binding; negative regulation of gluconeogenesis; positive regulation of ERK1 and ERK2 cascade; positive regulation of adiponectin secretion; positive regulation of cytokine secretion; positive regulation of protein kinase B signaling cascade; protein oligomerization,PF00386;PF01391;,,,,,,,,,C1QT3_MOUSE,Mus musculus (Mouse),cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206] comp117452_c1_seq1,396,40.6566,0.5524154,16,4,,4.00E-27,P34925,Tyrosine-protein kinase RYK (EC 2.7.10.1),Tyrosine-protein kinase RYK (EC 2.7.10.1),GO:0005524; GO:0016055; GO:0042813; GO:0007411; GO:0071679; GO:0022038; GO:0005737; GO:0005887; GO:0050919; GO:0048843; GO:0005634; GO:0043410; GO:0048705; GO:0004714,ATP binding; Wnt receptor signaling pathway; Wnt-activated receptor activity; axon guidance; commissural neuron axon guidance; corpus callosum development; cytoplasm; integral to plasma membrane; negative chemotaxis; negative regulation of axon extension involved in axon guidance; nucleus; positive regulation of MAPK cascade; skeletal system morphogenesis; transmembrane receptor protein tyrosine kinase activity,PF07714;PF02019;,4.00E-23,CHOYP_LOC100703289.1.1,,,,,,,RYK_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cell proliferation in midbrain [GO:0033278]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; non-canonical Wnt signaling pathway [GO:0035567]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of MAPK cascade [GO:0043410]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] comp117455_c0_seq1,1033,36.5924,0.41031784,38,124,,1.00E-68,O55057,"Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta)","Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta)",GO:0047555; GO:0005095; GO:0031410; GO:0030659; GO:0005829; GO:0007602; GO:0033124; GO:0007601,"3',5'-cyclic-GMP phosphodiesterase activity; GTPase inhibitor activity; cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; phototransduction; regulation of GTP catabolic process; visual perception",PF05351;,3.00E-92,CHOYP_PDE6D.2.2,,,,,,,PDE6D_MOUSE,Mus musculus (Mouse),phototransduction [GO:0007602]; visual perception [GO:0007601] comp117461_c0_seq1,818,46.6993,0.58395809,4,3,,,,,,,,,1.00E-32,CHOYP_PTHB1.1.1,,,,,,,,, comp117461_c0_seq2,830,46.747,0.57446043,25,0,,3.00E-57,Q6AX60,Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),GO:0034464; GO:0060170; GO:0005737; GO:0005815,BBSome; cilium membrane; cytoplasm; microtubule organizing center,PF14728;PF14727;,,,,,,,,,PTHB1_XENLA,Xenopus laevis (African clawed frog), comp117468_c1_seq1,368,41.0326,0.59410099,4,0,,6.00E-07,Q66HB5,Radial spoke head 10 homolog B,Radial spoke head 10 homolog B,,,PF02493;,,,,,,,,,RS10B_RAT,Rattus norvegicus (Rat), comp117468_c1_seq2,303,42.5743,0.70991951,3,0,,8.00E-21,Q5T089,MORN repeat-containing protein 1,MORN repeat-containing protein 1,,,PF02493;,1.00E-14,CHOYP_LOC100027727.1.1,,,,,,,MORN1_HUMAN,Homo sapiens (Human), comp117468_c2_seq1,247,45.749,0.5539927,2,5,,5.00E-11,Q8WYR4,Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein),Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein),GO:0005829; GO:0007126; GO:0005634,cytosol; meiosis; nucleus,PF02493;,,,,,,,,,RSPH1_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] comp117469_c0_seq1,642,48.7539,0.55227128,18,11,,,,,,,,,5.00E-11,CHOYP_SMP_148730.1.1,,,,,,,,, comp117484_c0_seq1,639,43.975,0.39449449,73,15,,2.00E-33,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp117491_c0_seq1,758,44.4591,0.66879434,18,66,,8.00E-20,A6NJL1,Zinc finger and SCAN domain-containing protein 5B,Zinc finger and SCAN domain-containing protein 5B,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF02023;PF00096;PF13912;,,,,,,,,,ZSA5B_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp117504_c0_seq1,1111,43.8344,0.75132658,108,79,,4.00E-66,Q8BWW9,Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2),Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2),GO:0005524; GO:0043297; GO:0043296; GO:0006915; GO:0007155; GO:0007049; GO:0051301; GO:0032154; GO:0005737; GO:0005856; GO:0010631; GO:0042826; GO:0030027; GO:0016020; GO:0030496; GO:0005634; GO:0032467; GO:0045931; GO:0004697; GO:0004674; GO:2000145; GO:0006355; GO:0007165; GO:0006351,"ATP binding; apical junction assembly; apical junction complex; apoptotic process; cell adhesion; cell cycle; cell division; cleavage furrow; cytoplasm; cytoskeleton; epithelial cell migration; histone deacetylase binding; lamellipodium; membrane; midbody; nucleus; positive regulation of cytokinesis; positive regulation of mitotic cell cycle; protein kinase C activity; protein serine/threonine kinase activity; regulation of cell motility; regulation of transcription, DNA-dependent; signal transduction; transcription, DNA-dependent",PF02185;PF00069;PF00433;,4.00E-34,CHOYP_LOC100377872.1.1,,,,,,,PKN2_MOUSE,Mus musculus (Mouse),"apical junction assembly [GO:0043297]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; epithelial cell migration [GO:0010631]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117518_c1_seq1,367,45.5041,0.44164744,11,20,,5.00E-06,Q1LZ80,PAXIP1-associated glutamate-rich protein 1 (PAXIP1-associated protein 1) (PTIP-associated protein 1),PAXIP1-associated glutamate-rich protein 1 (PAXIP1-associated protein 1) (PTIP-associated protein 1),GO:0035097,histone methyltransferase complex,PF15364;,,,,,,,,,PA1_BOVIN,Bos taurus (Bovine),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117522_c0_seq1,1418,45.3456,0.75984343,31,97,,1.00E-68,Q08AE8,Protein spire homolog 1 (Spir-1),Protein spire homolog 1 (Spir-1),GO:0005794; GO:0048193; GO:0005938; GO:0036089; GO:0030659; GO:0005856; GO:0051295; GO:0070649; GO:0046907; GO:0048471; GO:0005886; GO:0040038; GO:0015031; GO:0016192,Golgi apparatus; Golgi vesicle transport; cell cortex; cleavage furrow formation; cytoplasmic vesicle membrane; cytoskeleton; establishment of meiotic spindle localization; formin-nucleated actin cable assembly; intracellular transport; perinuclear region of cytoplasm; plasma membrane; polar body extrusion after meiotic divisions; protein transport; vesicle-mediated transport,PF16474;,,,,,,,,,SPIR1_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp117527_c0_seq1,1108,43.8628,0.58078078,33,49,,,,,,,,,1.00E-10,CHOYP_NAV2.2.3,,,,,,,,, comp117529_c0_seq1,570,35.9649,0.27362553,28,9,,2.00E-08,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp117536_c0_seq1,293,31.7406,0.823539,20,5,,,,,,,,,,,2.00E-11,ruditapes2_lrc4297,,,,,,, comp117545_c1_seq1,423,49.8818,0.47006915,15,30,,1.00E-70,Q6P286,"Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)","Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)",GO:0006096; GO:0005739; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrion; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF00676;PF16870;PF02779;,1.00E-60,CHOYP_BRAFLDRAFT_202318.1.1,,,,,,,DHTK1_XENLA,Xenopus laevis (African clawed frog),glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] comp117552_c1_seq1,385,50.6494,0.17155671,9,0,,,,,,,,,3.00E-18,CHOYP_MATN1.3.5,,,,,,,,, comp117559_c0_seq1,1372,34.1837,0.6372061,223,730,,9.00E-20,B5XE27,Alpha-endosulfine,Alpha-endosulfine,GO:0000086; GO:0051301; GO:0005737; GO:0007067; GO:0019212; GO:0051721; GO:0004864; GO:0008601,G2/M transition of mitotic cell cycle; cell division; cytoplasm; mitosis; phosphatase inhibitor activity; protein phosphatase 2A binding; protein phosphatase inhibitor activity; protein phosphatase type 2A regulator activity,PF04667;,,,,,,,,,ENSA_SALSA,Salmo salar (Atlantic salmon),cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067] comp117560_c0_seq1,510,46.2745,0.29412301,19,0,,9.00E-29,Q3UGY8,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,4.00E-18,CHOYP_LOC408471.1.1,,,,,,,BIG3_MOUSE,Mus musculus (Mouse),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp117590_c0_seq1,423,49.8818,0.82262101,8,68,,3.00E-45,P50393,Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],GO:0007568; GO:0019369; GO:0005509; GO:0047498; GO:0005544; GO:0005829; GO:0046697; GO:0001554; GO:0004622; GO:0005634; GO:0001542; GO:0048471; GO:0009395; GO:0043065; GO:0030501; GO:0008284; GO:0031622; GO:0031394; GO:0031340; GO:0051592; GO:0051384; GO:0009408; GO:0042542; GO:0032496; GO:0051597; GO:0010243; GO:0033280; GO:0043129; GO:0042588,aging; arachidonic acid metabolic process; calcium ion binding; calcium-dependent phospholipase A2 activity; calcium-dependent phospholipid binding; cytosol; decidualization; luteolysis; lysophospholipase activity; nucleus; ovulation from ovarian follicle; perinuclear region of cytoplasm; phospholipid catabolic process; positive regulation of apoptotic process; positive regulation of bone mineralization; positive regulation of cell proliferation; positive regulation of fever generation; positive regulation of prostaglandin biosynthetic process; positive regulation of vesicle fusion; response to calcium ion; response to glucocorticoid stimulus; response to heat; response to hydrogen peroxide; response to lipopolysaccharide; response to methylmercury; response to organonitrogen compound; response to vitamin D; surfactant homeostasis; zymogen granule,PF00168;PF01735;,2.00E-45,CHOYP_PA24A.2.3,,,,,,,PA24A_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; arachidonic acid metabolic process [GO:0019369]; decidualization [GO:0046697]; luteolysis [GO:0001554]; ovulation from ovarian follicle [GO:0001542]; phospholipid catabolic process [GO:0009395]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of inflammatory response [GO:0050729]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of vesicle fusion [GO:0031340]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to methylmercury [GO:0051597]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to vitamin D [GO:0033280]; surfactant homeostasis [GO:0043129] comp117597_c0_seq1,243,47.7366,0.65986694,9,5,,,,,,,,,6.00E-24,CHOYP_EDEM3.1.1,,,,,,,,, comp117597_c2_seq2,711,46.9761,0.43707883,4,14,,4.00E-122,Q9BZQ6,"ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)","ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)",GO:0005509; GO:0005788; GO:0005789; GO:0006516; GO:0004569; GO:0004571; GO:0043687; GO:0043161; GO:0018279; GO:0006457; GO:0006986,"calcium ion binding; endoplasmic reticulum lumen; endoplasmic reticulum membrane; glycoprotein catabolic process; glycoprotein endo-alpha-1,2-mannosidase activity; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; post-translational protein modification; proteasomal ubiquitin-dependent protein catabolic process; protein N-linked glycosylation via asparagine; protein folding; response to unfolded protein",PF01532;PF02225;,2.00E-93,CHOYP_EDEM3.1.1,,,,,,,EDEM3_HUMAN,Homo sapiens (Human),endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491] comp117600_c0_seq1,1371,41.6484,0.93576439,29,166,,5.00E-15,Q8YV57,Uncharacterized WD repeat-containing protein all2124,Uncharacterized WD repeat-containing protein all2124,GO:0004197; GO:0006508,cysteine-type endopeptidase activity; proteolysis,PF12894;PF00400;,1.00E-106,CHOYP_NR1AA.1.1,,,,,,,Y2124_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp117604_c1_seq1,226,47.7876,0.70938889,7,34,,4.00E-19,Q9Z2I7,Synaptic vesicle 2-related protein (SV2-related protein),Synaptic vesicle 2-related protein (SV2-related protein),GO:0030054; GO:0016021; GO:0015075; GO:0008021; GO:0030672,cell junction; integral to membrane; ion transmembrane transporter activity; synaptic vesicle; synaptic vesicle membrane,PF07690;PF00083;,3.00E-28,CHOYP_LOC100375275.1.1,,,,,,,SVOP_RAT,Rattus norvegicus (Rat), comp117606_c0_seq2,1056,43.9394,0.47416865,23,101,,1.00E-111,A4IF93,TBCC domain-containing protein 1,TBCC domain-containing protein 1,GO:0000902; GO:0005737; GO:0007010; GO:0051684; GO:0051661; GO:0030334; GO:0008360; GO:0031616,cell morphogenesis; cytoplasm; cytoskeleton organization; maintenance of Golgi location; maintenance of centrosome location; regulation of cell migration; regulation of cell shape; spindle pole centrosome,PF07986;,2.00E-94,CHOYP_LOC100370965.1.1,,,,,,,TBCC1_BOVIN,Bos taurus (Bovine),cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; maintenance of centrosome location [GO:0051661]; maintenance of Golgi location [GO:0051684]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360] comp117609_c0_seq1,656,36.128,0.47830629,43,67,,2.00E-77,A5D8N2,Protein DPCD,Protein DPCD,,,,2.00E-28,CHOYP_DPCD.1.1,,,,,,,DPCD_XENLA,Xenopus laevis (African clawed frog), comp117617_c0_seq1,409,43.2763,0.73817314,2,28,,1.00E-56,Q52KZ7,Selenium-binding protein 1-A,Selenium-binding protein 1-A,GO:0005829; GO:0016020; GO:0005634; GO:0015031; GO:0008430,cytosol; membrane; nucleus; protein transport; selenium binding,PF05694;,2.00E-14,CHOYP_SBP1.2.2,,,,,,,SBP1A_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp117617_c1_seq1,414,44.4444,0.74107575,1,52,,5.00E-21,Q21950,Putative selenium-binding protein,Putative selenium-binding protein,GO:0008430,selenium binding,PF05694;,,,1.00E-32,ruditapes_lrc32824,,,,,SBP_CAEEL,Caenorhabditis elegans, comp117622_c0_seq1,525,36.381,0.2532508,0,0,,,,,,,,,,,2.00E-14,ruditapes_c7656,,,,,,, comp117622_c0_seq2,652,35.7362,0.37126468,3,8,,4.00E-07,Q32P65,"Mimitin, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2) (NDUFA12-like protein)","Mimitin, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2) (NDUFA12-like protein)",GO:0005739,mitochondrion,PF05071;,,,,,,,,,MIMIT_BOVIN,Bos taurus (Bovine),cellular respiration [GO:0045333] comp117634_c1_seq1,1064,46.3346,0.61530262,49,152,,2.00E-82,Q9Y4F1,"FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)","FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)",GO:0030676; GO:0030054; GO:0005856; GO:0005829; GO:0030425; GO:0048813; GO:0043197; GO:0031234; GO:0030175; GO:0010923; GO:0005543; GO:0035023; GO:0045202; GO:0007416,Rac guanyl-nucleotide exchange factor activity; cell junction; cytoskeleton; cytosol; dendrite; dendrite morphogenesis; dendritic spine; extrinsic to internal side of plasma membrane; filopodium; negative regulation of phosphatase activity; phospholipid binding; regulation of Rho protein signal transduction; synapse; synapse assembly,PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;,1.00E-35,CHOYP_FARP2.1.1,,,,,,,FARP1_HUMAN,Homo sapiens (Human),dendrite morphogenesis [GO:0048813]; negative regulation of phosphatase activity [GO:0010923]; regulation of Rho protein signal transduction [GO:0035023]; synapse assembly [GO:0007416] comp117638_c0_seq1,528,46.5909,0.59540733,38,52,,4.00E-68,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,6.00E-98,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp117641_c1_seq1,290,45.1724,0.54418599,2,19,,2.00E-30,Q92485,Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),GO:0005615; GO:0016798; GO:0006685; GO:0004767,"extracellular space; hydrolase activity, acting on glycosyl bonds; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity",PF00149;,,,,,,,,,ASM3B_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] comp117649_c0_seq1,1077,35.7474,0.40734178,1157,355,,3.00E-17,Q99932,Sperm-associated antigen 8 (HSD-1) (Sperm membrane protein 1) (SMP-1) (Sperm membrane protein BS-84),Sperm-associated antigen 8 (HSD-1) (Sperm membrane protein 1) (SMP-1) (Sperm membrane protein BS-84),GO:0001669; GO:0016020; GO:0005634; GO:0032092; GO:0045944,acrosomal vesicle; membrane; nucleus; positive regulation of protein binding; positive regulation of transcription from RNA polymerase II promoter,,3.00E-36,CHOYP_BRAFLDRAFT_264461.1.1,6.00E-100,ruditapes2_c230,,,,,SPAG8_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell differentiation [GO:0030154]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] comp117656_c0_seq1,404,44.0594,0.87819416,4,43,,9.00E-45,Q9D531,Nucleoredoxin-like protein 2 (Rod-derived cone viability factor 2) (RdCVF2),Nucleoredoxin-like protein 2 (Rod-derived cone viability factor 2) (RdCVF2),GO:0007608; GO:0007601,sensory perception of smell; visual perception,PF13905;,,,2.00E-17,ruditapes2_c1679,,,,,NXNL2_MOUSE,Mus musculus (Mouse),photoreceptor cell maintenance [GO:0045494]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601] comp117661_c0_seq2,507,44.5759,0.87696512,7,8,,3.00E-13,P55786,Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S),Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S),GO:0004177; GO:0002474; GO:0071456; GO:0005829; GO:0008237; GO:0005634; GO:0000209; GO:0006508; GO:0008270,aminopeptidase activity; antigen processing and presentation of peptide antigen via MHC class I; cellular response to hypoxia; cytosol; metallopeptidase activity; nucleus; protein polyubiquitination; proteolysis; zinc ion binding,PF11838;PF01433;,1.00E-49,CHOYP_APN.1.3,,,,,,,PSA_HUMAN,Homo sapiens (Human),cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209] comp117689_c0_seq1,710,41.2676,0.68326101,37,51,,3.00E-06,Q9Y2I6,Ninein-like protein,Ninein-like protein,GO:0000086; GO:0005509; GO:0005829; GO:0005874; GO:0005815,G2/M transition of mitotic cell cycle; calcium ion binding; cytosol; microtubule; microtubule organizing center,PF13499;,,,,,,,,,NINL_HUMAN,Homo sapiens (Human),G2/M transition of mitotic cell cycle [GO:0000086]; microtubule cytoskeleton organization [GO:0000226] comp117699_c0_seq1,926,48.2721,0.80348814,28,20,,4.00E-47,O17583,Protein lin-10 (Abnormal cell lineage protein 10),Protein lin-10 (Abnormal cell lineage protein 10),GO:0032580; GO:0000138; GO:0008105; GO:0007275; GO:0043005; GO:0007270; GO:0043025; GO:0005886; GO:0040026; GO:0050975; GO:0030140,Golgi cisterna membrane; Golgi trans cisterna; asymmetric protein localization; multicellular organismal development; neuron projection; neuron-neuron synaptic transmission; neuronal cell body; plasma membrane; positive regulation of vulval development; sensory perception of touch; trans-Golgi network transport vesicle,PF00595;PF00640;,2.00E-75,CHOYP_LOC657912.1.1,,,,,,,LIN10_CAEEL,Caenorhabditis elegans,asymmetric protein localization [GO:0008105]; nervous system development [GO:0007399]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of vulval development [GO:0040026]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to early endosome [GO:1902946]; receptor localization to synapse [GO:0097120]; sensory perception of touch [GO:0050975]; transport [GO:0006810] comp117714_c0_seq1,483,50.5176,0.75405051,24,7,,1.00E-12,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,,,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp117716_c1_seq1,272,37.1324,0.58334122,8,4,,3.00E-06,Q8NFW9,Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c),Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c),GO:0015629; GO:0031045; GO:0000145; GO:0006886; GO:0042470; GO:0048471; GO:0001750; GO:0032024; GO:0045202; GO:0030133; GO:0008270,actin cytoskeleton; dense core granule; exocyst; intracellular protein transport; melanosome; perinuclear region of cytoplasm; photoreceptor outer segment; positive regulation of insulin secretion; synapse; transport vesicle; zinc ion binding,PF02318;PF04698;,,,,,,,,,MYRIP_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; positive regulation of insulin secretion [GO:0032024] comp117717_c0_seq1,659,47.041,0.57750133,39,6,,1.00E-70,O75096,Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),GO:0016055; GO:0005509; GO:0030154; GO:0009953; GO:0042733; GO:0006897; GO:0030198; GO:0001942; GO:0016021; GO:0001822; GO:0090090; GO:0030279; GO:0042475; GO:0005886; GO:0009954; GO:0043113; GO:0001932; GO:0051124,Wnt receptor signaling pathway; calcium ion binding; cell differentiation; dorsal/ventral pattern formation; embryonic digit morphogenesis; endocytosis; extracellular matrix organization; hair follicle development; integral to membrane; kidney development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of ossification; odontogenesis of dentin-containing tooth; plasma membrane; proximal/distal pattern formation; receptor clustering; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF12662;PF00057;PF00058;,4.00E-19,CHOYP_LRP4.5.5,,,,,,,LRP4_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] comp117719_c0_seq1,373,41.8231,0.615136,2,0,,1.00E-35,Q2KJG2,Ubiquitin-fold modifier 1,Ubiquitin-fold modifier 1,GO:0005737; GO:0005634; GO:0071569,cytoplasm; nucleus; protein ufmylation,PF03671;,,,,,,,,,UFM1_BOVIN,Bos taurus (Bovine),protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976] comp117722_c0_seq2,749,41.6555,0.47446418,12,15,,9.00E-94,Q9D4H8,Cullin-2 (CUL-2),Cullin-2 (CUL-2),GO:0031462; GO:0030163; GO:0016567; GO:0006511,Cul2-RING ubiquitin ligase complex; protein catabolic process; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,4.00E-64,CHOYP_CUL2.1.1,,,,,,,CUL2_MOUSE,Mus musculus (Mouse),protein catabolic process [GO:0030163]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp117723_c0_seq1,272,43.75,0.54290507,8,31,,3.00E-07,C0Q7M8,Lipoate-protein ligase A (EC 2.7.7.63) (Lipoate--protein ligase),Lipoate-protein ligase A (EC 6.3.1.20) (Lipoate--protein ligase),GO:0005524; GO:0005737; GO:0016979; GO:0018055; GO:0016740,ATP binding; cytoplasm; lipoate-protein ligase activity; peptidyl-lysine lipoylation; transferase activity,PF03099;PF10437;,,,,,,,,,LPLA_SALPC,Salmonella paratyphi C (strain RKS4594),peptidyl-lysine lipoylation [GO:0018055] comp117723_c1_seq1,228,38.1579,0.62365034,0,29,,2.00E-15,O46419,"Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase)","Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase)",GO:0005739; GO:0009249; GO:0016746,"mitochondrion; protein lipoylation; transferase activity, transferring acyl groups",,3.00E-14,CHOYP_LIPT.1.1,,,,,,,LIPT_BOVIN,Bos taurus (Bovine),protein lipoylation [GO:0009249] comp117733_c0_seq1,460,38.6957,0.5243958,0,25,,7.00E-14,O14628,Zinc finger protein 195,Zinc finger protein 195,GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZN195_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117733_c0_seq2,393,39.6947,0.52229004,1,18,,3.00E-13,A6QPT6,Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274),Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274),GO:0005813; GO:0005737; GO:0046872; GO:0005166; GO:0005730; GO:0005634; GO:0043565; GO:0000981,centrosome; cytoplasm; metal ion binding; neurotrophin p75 receptor binding; nucleolus; nucleus; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF01352;PF02023;PF00096;,,,,,,,,,ZN274_BOVIN,Bos taurus (Bovine),"regulation of histone H3-K9 trimethylation [GO:1900112]; transcription, DNA-templated [GO:0006351]" comp117739_c0_seq1,369,40.3794,0.4676813,7,11,,,,,,,,,3.00E-11,CHOYP_GWL.1.1,,,,,,,,, comp117740_c0_seq1,528,43.5606,0.40027383,18,2,,2.00E-27,Q9Y4D2,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0008219; GO:0046340; GO:0071926; GO:0016021; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0030168; GO:0004806,arachidonic acid metabolic process; cell death; diacylglycerol catabolic process; endocannabinoid signaling pathway; integral to membrane; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; platelet activation; triglyceride lipase activity,PF01764;,,,,,,,,,DGLA_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136] comp117746_c0_seq1,869,46.4902,0.38652402,37,40,,9.00E-110,Q8BMG7,Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0030234; GO:0043547; GO:0046982,GTPase activator activity; cytoplasm; enzyme regulator activity; positive regulation of GTPase activity; protein heterodimerization activity,PF14656;PF14655;,1.00E-40,CHOYP_RBGPR.1.1,,,,,,,RBGPR_MOUSE,Mus musculus (Mouse),establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp117753_c0_seq1,995,38.0905,0.3652678,385,1539,,,,,,,,,1.00E-41,CHOYP_LOC100370323.1.1,,,,,,,,, comp117759_c0_seq1,775,37.6774,0.87169864,0,23,,9.00E-27,O02367,Calmodulin (CaM) (Ci-CaM),Calmodulin (CaM) (Ci-CaM),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALM_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis), comp117759_c0_seq2,676,38.4615,0.98718243,0,12,,3.00E-10,P05934,Calmodulin (CaM) (Fragment),Calmodulin (CaM) (Fragment),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALM_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp117765_c0_seq4,1023,35.9726,0.57904817,0,0,,1.00E-30,Q0VFV7,BTB/POZ domain-containing protein KCTD7,BTB/POZ domain-containing protein KCTD7,GO:0005829; GO:0005886; GO:0051260,cytosol; plasma membrane; protein homooligomerization,PF02214;,5.00E-33,CHOYP_KCTD7.1.1,,,,,,,KCTD7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein homooligomerization [GO:0051260] comp117765_c0_seq5,1133,38.0406,0.71283708,0,4,,6.00E-28,Q8BJK1,BTB/POZ domain-containing protein KCTD7,BTB/POZ domain-containing protein KCTD7,GO:0005829; GO:0005886; GO:0051260,cytosol; plasma membrane; protein homooligomerization,PF02214;,,,,,,,,,KCTD7_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp117765_c0_seq6,1161,38.0706,0.6931468,0,0,,,,,,,,,9.00E-18,CHOYP_KCTD7.1.1,,,,,,,,, comp117767_c0_seq1,1001,39.2607,0.6277874,12,147,,1.00E-26,Q14590,Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6),Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN235_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117772_c0_seq1,936,42.5214,0.45048128,31,50,,1.00E-61,Q64512,Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),GO:0005737; GO:0005856; GO:0030027; GO:0005634; GO:0004725,cytoplasm; cytoskeleton; lamellipodium; nucleus; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,2.00E-25,CHOYP_PTP.1.1,,,,,,,PTN13_MOUSE,Mus musculus (Mouse),peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp117773_c0_seq1,369,40.6504,0.66535285,7,13,,9.00E-25,Q5VTD9,Zinc finger protein Gfi-1b (Growth factor independent protein 1B) (Potential regulator of CDKN1A translocated in CML),Zinc finger protein Gfi-1b (Growth factor independent protein 1B) (Potential regulator of CDKN1A translocated in CML),GO:0003677; GO:0008283; GO:0016568; GO:0046872; GO:0007275; GO:0000122; GO:0016363; GO:0005667; GO:0006366,DNA binding; cell proliferation; chromatin modification; metal ion binding; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; transcription factor complex; transcription from RNA polymerase II promoter,PF00096;PF13912;,,,,,,,,,GFI1B_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of histone H3-K4 methylation [GO:0051569]; transcription from RNA polymerase II promoter [GO:0006366] comp117773_c1_seq1,470,39.3617,0.38543546,6,10,,8.00E-18,A8MT65,Zinc finger protein 891,Zinc finger protein 891,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN891_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp117774_c0_seq1,203,43.8424,0.41633663,0,10,,6.00E-14,Q7RWM9,Palmitoyltransferase SWF1 (EC 2.3.1.225),Palmitoyltransferase SWF1 (EC 2.3.1.225),GO:0005789; GO:0016021; GO:0016746; GO:0008270,"endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,SWF1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), comp117774_c1_seq1,429,40.7925,0.67451347,2,76,,2.00E-09,Q2TGI5,Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Membrane-associated zinc finger protein DHHC25) (Zinc finger DHHC domain-containing protein 24) (DHHC-24),Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Membrane-associated zinc finger protein DHHC25) (Zinc finger DHHC domain-containing protein 24) (DHHC-24),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDH24_RAT,Rattus norvegicus (Rat), comp117777_c0_seq1,668,38.3234,0.49300037,3,151,,2.00E-41,Q5BKH5,PRELI domain-containing protein 2,PRELI domain-containing protein 2,,,PF04707;,,,,,,,,,PRLD2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp117779_c0_seq1,645,43.2558,0.43248636,19,97,,,,,,,,,2.00E-61,CHOYP_CDC23.1.1,,,,,,,,, comp117779_c1_seq1,418,41.6268,0.45642963,3,24,,2.00E-74,A1A4R8,Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8),Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8),GO:0005680; GO:0051301; GO:0007080; GO:0070979; GO:0030071,anaphase-promoting complex; cell division; mitotic metaphase plate congression; protein K11-linked ubiquitination; regulation of mitotic metaphase/anaphase transition,PF04049;PF13414;PF13181;,,,,,,,,,CDC23_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071] comp117801_c0_seq1,966,35.6108,0.49036564,1525,91,,3.00E-46,Q5M7F8,UPF0573 protein C2orf70 homolog A,UPF0573 protein C2orf70 homolog A,,,PF10629;,6.00E-82,CHOYP_LOC100371099.1.1,,,3.00E-80,CU987737.p.cg.6,5,,C070A_XENLA,Xenopus laevis (African clawed frog), comp117804_c0_seq1,573,41.3613,0.08176663,0,0,,9.00E-67,Q9NXL6,SID1 transmembrane family member 1,SID1 transmembrane family member 1,GO:0051033; GO:0033227; GO:0016021,RNA transmembrane transporter activity; dsRNA transport; integral to membrane,PF13965;,,,,,,,,,SIDT1_HUMAN,Homo sapiens (Human),dsRNA transport [GO:0033227] comp117804_c0_seq3,460,43.913,0.09041918,0,0,,,,,,,,,1.00E-56,CHOYP_SIDT1.1.2,,,,,,,,, comp117805_c0_seq1,1146,39.9651,0.89785661,27,4,,2.00E-10,Q9Y5G4,Protocadherin gamma-A9 (PCDH-gamma-A9),Protocadherin gamma-A9 (PCDH-gamma-A9),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG9_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp117805_c0_seq2,831,37.1841,0.95065732,4,0,,3.00E-16,Q9P2E7,Protocadherin-10,Protocadherin-10,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;,,,,,,,,,PCD10_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp117807_c0_seq1,1296,45.5247,0.37259859,6,12,,4.00E-23,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,,,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp117807_c0_seq2,1091,46.8378,0.36801502,0,0,,,,,,,,,2.00E-20,CHOYP_LOC100166052.1.1,,,,,,,,, comp117811_c2_seq1,1730,47.6301,0.65376671,68,94,,1.00E-68,Q9Y2K2,Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK),Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK),GO:0005524; GO:0005737; GO:0000287; GO:0004674,ATP binding; cytoplasm; magnesium ion binding; protein serine/threonine kinase activity,PF00069;,2.00E-41,CHOYP_SIK3.1.1,,,,,,,SIK3_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468] comp117825_c0_seq1,735,45.034,0.38941871,36,57,,3.00E-22,Q5XGZ9,Major facilitator superfamily domain-containing protein 6-like protein B,Major facilitator superfamily domain-containing protein 6-like protein B,GO:0016021,integral to membrane,PF12832;,,,,,,,,,MF6LB_XENLA,Xenopus laevis (African clawed frog), comp117825_c1_seq1,629,38.6328,0.35846463,39,10,,,,,,,,,6.00E-23,CHOYP_BRAFLDRAFT_275402.1.1,,,,,,,,, comp117832_c0_seq1,529,45.3686,0.99382257,26,4,,2.00E-06,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp117841_c0_seq1,680,47.0588,0.94299144,35,55,,1.00E-118,Q9Z1N9,Protein unc-13 homolog B (Munc13-2) (munc13),Protein unc-13 homolog B (Munc13-2) (munc13),GO:0005794; GO:0030054; GO:0019992; GO:0060384; GO:0035556; GO:0016020; GO:0046872; GO:0031594; GO:0007528; GO:0001566; GO:0048172; GO:0035249; GO:0016081; GO:0016082,"Golgi apparatus; cell junction; diacylglycerol binding; innervation; intracellular signal transduction; membrane; metal ion binding; neuromuscular junction; neuromuscular junction development; non-kinase phorbol ester receptor activity; regulation of short-term neuronal synaptic plasticity; synaptic transmission, glutamatergic; synaptic vesicle docking involved in exocytosis; synaptic vesicle priming",PF00130;PF00168;PF06292;PF10540;,5.00E-119,CHOYP_LOC100650524.1.2,,,,,,,UN13B_MOUSE,Mus musculus (Mouse),"chemical synaptic transmission [GO:0007268]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic vesicle priming [GO:0010808]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082]" comp117881_c0_seq1,243,32.5103,1.25130324,4,12,,1.00E-09,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,1.00E-14,CHOYP_LOC100892567.8.8,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp117886_c0_seq1,201,38.3085,1.38170315,3,6,,2.00E-09,Q7T3S3,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST-1) (C4ST1) (zC4ST-1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST-1) (C4ST1) (zC4ST-1),GO:0000139; GO:0016051; GO:0047756; GO:0030206; GO:0016021; GO:0008045; GO:0007517,Golgi membrane; carbohydrate biosynthetic process; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; integral to membrane; motor neuron axon guidance; muscle organ development,PF03567;,,,,,,,,,CHSTB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517] comp117889_c0_seq1,608,46.7105,0.33965513,0,0,,1.00E-34,Q8IVU3,Probable E3 ubiquitin-protein ligase HERC6 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 6),Probable E3 ubiquitin-protein ligase HERC6 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 6),GO:0005737; GO:0005829; GO:0005634; GO:0042787; GO:0004842,cytoplasm; cytosol; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC6_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp117889_c0_seq2,729,46.3649,0.34165021,11,20,,4.00E-48,Q15034,Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3),Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3),GO:0005737; GO:0016023; GO:0005634; GO:0042787; GO:0004842,cytoplasm; cytoplasmic membrane-bounded vesicle; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC3_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp117893_c0_seq2,330,42.1212,0.91166091,1,60,,1.00E-10,Q7REH6,Glutathione S-transferase (EC 2.5.1.18),Glutathione S-transferase (EC 2.5.1.18),GO:0004364,glutathione transferase activity,PF14497;PF02798;,,,,,,,,,GST_PLAYO,Plasmodium yoelii yoelii, comp117922_c0_seq1,1702,36.0165,0.58222242,1542,70,,4.00E-72,Q9UHP6,Rhabdoid tumor deletion region protein 1,Radial spoke head 14 homolog (Rhabdoid tumor deletion region protein 1),,,PF00514;,3.00E-95,CHOYP_BRAFLDRAFT_279978.1.1,2.00E-127,ruditapes_c28256,7.00E-67,AM859590.p.cg.6,5,,RTDR1_HUMAN,Homo sapiens (Human), comp117923_c0_seq1,452,44.9115,0.43972259,25,0,,2.00E-64,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,1.00E-48,CHOYP_DYH8.2.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp117923_c2_seq1,343,48.688,0.75439238,6,0,,,,,,,,,1.00E-78,CHOYP_DNAH5.1.2,,,,,,,,, comp117923_c2_seq2,375,45.6,0.56626909,2,9,,2.00E-69,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,6.00E-103,CHOYP_DNAH5.2.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp117928_c0_seq1,414,43.2367,0.57392842,4,71,,,,,,,,,3.00E-12,CHOYP_SMP_149390.1.1,,,,,,,,, comp117939_c0_seq1,236,47.0339,0.4619966,13,6,,2.00E-13,Q6DCF2,MMS19 nucleotide excision repair protein homolog (MMS19-like protein),MMS19 nucleotide excision repair protein homolog (MMS19-like protein),GO:0097361; GO:0006281; GO:0016226; GO:0005634; GO:0005819,CIA complex; DNA repair; iron-sulfur cluster assembly; nucleus; spindle,PF12460;,,,,,,,,,MMS19_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226] comp117951_c0_seq1,704,42.1875,0.41731256,17,100,,5.00E-35,Q3TWL2,"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B)","Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B)",GO:0016787; GO:0016021; GO:0031902; GO:0005765,hydrolase activity; integral to membrane; late endosome membrane; lysosomal membrane,PF09788;,4.00E-13,CHOYP_LOC100368816.2.2,,,,,,,TM55B_MOUSE,Mus musculus (Mouse),phosphatidylinositol dephosphorylation [GO:0046856] comp117955_c1_seq3,461,38.8286,0.58644602,0,0,,2.00E-10,Q8C170,Unconventional myosin-IXa (Unconventional myosin-9a),Unconventional myosin-IXa (Unconventional myosin-9a),GO:0005524; GO:0005096; GO:0016021; GO:0035556; GO:0046872; GO:0003774; GO:0016459; GO:0043547,ATP binding; GTPase activator activity; integral to membrane; intracellular signal transduction; metal ion binding; motor activity; myosin complex; positive regulation of GTPase activity,PF00612;PF00063;PF00788;PF00620;,,,,,,,,,MYO9A_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556] comp117971_c0_seq1,345,49.2754,0.48863565,22,5,,7.00E-13,A7T395,Spastin (EC 3.6.4.3),Spastin (EC 3.6.4.3),GO:0005524; GO:0005737; GO:0016021; GO:0005874; GO:0005815; GO:0051013; GO:0008568; GO:0005634; GO:0031117; GO:0034214,ATP binding; cytoplasm; integral to membrane; microtubule; microtubule organizing center; microtubule severing; microtubule-severing ATPase activity; nucleus; positive regulation of microtubule depolymerization; protein hexamerization,PF00004;PF09336;,,,,,,,,,SPAST_NEMVE,Nematostella vectensis (Starlet sea anemone),cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214] comp117971_c3_seq1,426,43.1925,0.41786163,17,14,,5.00E-78,A0JMA9,Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 3.6.4.3) (p60 katanin-like 2),Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 3.6.4.3) (p60 katanin-like 2),GO:0005524; GO:0005737; GO:0005874; GO:0051013; GO:0008568,ATP binding; cytoplasm; microtubule; microtubule severing; microtubule-severing ATPase activity,PF00004;PF08513;,2.00E-91,CHOYP_KATL2.2.2,,,,,,,KATL2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013] comp117975_c0_seq2,268,37.6866,0.97074327,4,0,,,,,,,,,,,1.00E-12,ruditapes_c2998,,,,,,, comp117982_c0_seq1,572,50.5245,0.54995849,30,22,,5.00E-50,Q60841,Reelin (EC 3.4.21.-) (Reeler protein),Reelin (EC 3.4.21.-) (Reeler protein),GO:0097114; GO:0008306; GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0016358; GO:0005615; GO:0010001; GO:0021766; GO:0097477; GO:0007616; GO:0046872; GO:0018108; GO:0032793; GO:0032008; GO:2000969; GO:0061003; GO:2000463; GO:1902078; GO:1900273; GO:0010976; GO:0014068; GO:0061098; GO:0051057; GO:0090129; GO:0051968; GO:0097107; GO:0097119; GO:0005578; GO:0006508; GO:0097120; GO:0038026; GO:2000310; GO:0050795; GO:0048265; GO:0008236; GO:0021511; GO:0021517,"N-methyl-D-aspartate receptor clustering; associative learning; axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; dendrite development; extracellular space; glial cell differentiation; hippocampus development; lateral motor column neuron migration; long-term memory; metal ion binding; peptidyl-tyrosine phosphorylation; positive regulation of CREB transcription factor activity; positive regulation of TOR signaling cascade; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; positive regulation of dendritic spine morphogenesis; positive regulation of excitatory postsynaptic membrane potential; positive regulation of lateral motor column neuron migration; positive regulation of long-term synaptic potentiation; positive regulation of neuron projection development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of protein tyrosine kinase activity; positive regulation of small GTPase mediated signal transduction; positive regulation of synapse maturation; positive regulation of synaptic transmission, glutamatergic; postsynaptic density assembly; postsynaptic density protein 95 clustering; proteinaceous extracellular matrix; proteolysis; receptor localization to synapse; reelin-mediated signaling pathway; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of behavior; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development",PF02014;,,,,,,,,,RELN_MOUSE,Mus musculus (Mouse),"associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex development [GO:0021987]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density assembly [GO:0097107]; postsynaptic density protein 95 clustering [GO:0097119]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of gene expression [GO:0010468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]" comp117984_c0_seq1,2062,41.7556,0.59238585,0,6,,1.00E-132,Q68CP4,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0005975; GO:0006027; GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0044281; GO:0016746,"carbohydrate metabolic process; glycosaminoglycan catabolic process; heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; small molecule metabolic process; transferase activity, transferring acyl groups",PF07786;,3.00E-46,CHOYP_HGSNAT.2.2,,,,,,,HGNAT_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp117992_c0_seq1,380,36.8421,0.2340311,11,27,,2.00E-21,A7T167,Protein GDAP2 homolog,Protein GDAP2 homolog,,,PF13716;PF01661;,2.00E-32,CHOYP_GDAP2.1.1,,,,,,,GDAP2_NEMVE,Nematostella vectensis (Starlet sea anemone), comp117994_c1_seq1,701,44.9358,0.8798433,5,125,,2.00E-25,Q7LFX5,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0030206; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; chondroitin sulfate biosynthetic process; hexose biosynthetic process; integral to membrane,,4.00E-13,CHOYP_CHST15.2.3,,,,,,,CHSTF_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319] comp117994_c2_seq1,626,36.1022,0.64014928,16,106,,4.00E-17,Q8WTN9,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST) (Fragments),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST) (Fragments),GO:0000139; GO:0050659,Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,PF00685;,,,,,,,,,CHSTF_OMMSL,Nototodarus sloanii (Wellington flying squid) (Ommastrephes sloanei), comp118001_c0_seq1,417,46.5228,0.77917115,1,102,,2.00E-21,O77404,Tryparedoxin (TryX),Tryparedoxin (TryX),GO:0045454; GO:0055114,cell redox homeostasis; oxidation-reduction process,PF13905;,,,,,,,,,TYPX_TRYBB,Trypanosoma brucei brucei,cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114] comp118002_c0_seq1,699,41.6309,0.30057313,5,0,,,,,,,,,5.00E-88,CHOYP_LOC100643035.1.1,,,,,,,,, comp118002_c0_seq2,729,46.0905,0.36730949,12,15,,2.00E-104,P18688,"Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)","Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)",GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,,,,,,,,,KPB1_RABIT,Oryctolagus cuniculus (Rabbit),glycogen metabolic process [GO:0005977] comp118003_c0_seq1,936,40.3846,0.71022792,31,88,,5.00E-34,Q96N64,PWWP domain-containing protein 2A,PWWP domain-containing protein 2A,,,PF00855;,1.00E-39,CHOYP_BRAFLDRAFT_124247.1.1,,,,,,,PWP2A_HUMAN,Homo sapiens (Human), comp118005_c0_seq1,635,45.1969,0.43625782,32,15,,2.00E-69,P23470,Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48),GO:0005887; GO:0007169; GO:0005001,integral to plasma membrane; transmembrane receptor protein tyrosine kinase signaling pathway; transmembrane receptor protein tyrosine phosphatase activity,PF00194;PF00041;PF00102;,5.00E-75,CHOYP_LOC660278.2.2,,,,,,,PTPRG_HUMAN,Homo sapiens (Human),negative regulation of epithelial cell migration [GO:0010633]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp118012_c0_seq1,1262,44.1363,0.59198537,40,27,,2.00E-33,P56941,Niemann-Pick C1 protein,Niemann-Pick C1 protein,GO:0008206; GO:0015485; GO:0042632; GO:0008203; GO:0030301; GO:0005783; GO:0005576; GO:0008158; GO:0005887; GO:0031902; GO:0005765; GO:0007041; GO:0005764; GO:0005635; GO:0048471; GO:0006486,bile acid metabolic process; cholesterol binding; cholesterol homeostasis; cholesterol metabolic process; cholesterol transport; endoplasmic reticulum; extracellular region; hedgehog receptor activity; integral to plasma membrane; late endosome membrane; lysosomal membrane; lysosomal transport; lysosome; nuclear envelope; perinuclear region of cytoplasm; protein glycosylation,PF16414;PF02460;PF12349;,,,,,,,,,NPC1_PIG,Sus scrofa (Pig),bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; lysosomal transport [GO:0007041]; protein glycosylation [GO:0006486] comp118015_c0_seq1,388,41.4948,0.79139806,3,5,,3.00E-42,Q6DE92,Plexin domain-containing protein 2,Plexin domain-containing protein 2,GO:0016021; GO:0007275; GO:0004872,integral to membrane; multicellular organismal development; receptor activity,PF01437;,1.00E-17,CHOYP_PXDC2.3.3,,,,,,,PXDC2_XENLA,Xenopus laevis (African clawed frog), comp118022_c0_seq1,788,40.2284,0.9184745,29,80,,6.00E-51,Q2NL00,Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),GO:0005737; GO:0004364,cytoplasm; glutathione transferase activity,PF00043;PF02798;,,,8.00E-46,ruditapes2_c567,,,,,GSTT1_BOVIN,Bos taurus (Bovine),glutathione metabolic process [GO:0006749] comp118027_c0_seq1,768,43.6198,0.60965869,1,9,,2.00E-68,Q9YH16,LIM domain only protein 3 (LMO-3) (LIM domain only protein 1) (LMO-1) (xLMO1),LIM domain only protein 3 (LMO-3) (LIM domain only protein 1) (LMO-1) (xLMO1),GO:0008270,zinc ion binding,PF00412;,5.00E-101,CHOYP_AGAP_AGAP010391.1.2,,,,,,,LMO3_XENLA,Xenopus laevis (African clawed frog), comp118027_c0_seq2,1053,42.2602,0.36637664,2,21,,3.00E-68,Q8JFQ2,Rhombotin-1 (LIM domain only protein 1) (LMO-1),Rhombotin-1 (LIM domain only protein 1) (LMO-1),GO:0005634; GO:0008270,nucleus; zinc ion binding,PF00412;,7.00E-101,CHOYP_AGAP_AGAP010391.2.2,,,,,,,RBTN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp118035_c0_seq1,408,38.9706,0.45387083,7,19,,5.00E-06,O93209,Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (p42In)],Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)],GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0030430; GO:0042025; GO:0046872; GO:0090305; GO:0006508; GO:0004523; GO:0046718; GO:0075732; GO:0019012,DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; host cell cytoplasm; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; viral entry into host cell; viral penetration into host nucleus; virion,PF00075;PF00665;PF00078;PF03539;,,,,,,,,,POL_FFV,Feline foamy virus (FFV) (Feline syncytial virus),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] comp118036_c0_seq1,1305,37.8544,0.22013228,71,74,,5.00E-16,Q15149,Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),GO:0006921; GO:0043034; GO:0005829; GO:0030198; GO:0005925; GO:0030056; GO:0031581; GO:0045111; GO:0042383; GO:0016528; GO:0008307,cellular component disassembly involved in execution phase of apoptosis; costamere; cytosol; extracellular matrix organization; focal adhesion; hemidesmosome; hemidesmosome assembly; intermediate filament cytoskeleton; sarcolemma; sarcoplasm; structural constituent of muscle,PF00307;PF00681;PF03501;,,,,,,,,,PLEC_HUMAN,Homo sapiens (Human),hemidesmosome assembly [GO:0031581] comp118050_c0_seq1,261,44.0613,0.32587543,28,65,,5.00E-06,Q9NUL7,Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28),Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28),GO:0005524; GO:0008026; GO:0003723; GO:0042645; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA binding; mitochondrial nucleoid; nucleolus,PF00270;PF00271;,,,,,,,,,DDX28_HUMAN,Homo sapiens (Human),mitochondrial large ribosomal subunit assembly [GO:1902775]; RNA secondary structure unwinding [GO:0010501] comp118052_c0_seq1,405,46.9136,0.6621662,13,11,,5.00E-37,Q05096,Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1),Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1),GO:0005524; GO:0003779; GO:0051017; GO:0030048; GO:0030898; GO:0005903; GO:0005516; GO:0005737; GO:0005856; GO:0030175; GO:0000146; GO:0016459; GO:0007399; GO:0005547; GO:0005546; GO:0005886,"ATP binding; actin binding; actin filament bundle assembly; actin filament-based movement; actin-dependent ATPase activity; brush border; calmodulin binding; cytoplasm; cytoskeleton; filopodium; microfilament motor activity; myosin complex; nervous system development; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane",PF00612;PF00063;PF06017;,1.00E-28,CHOYP_MYO1B.1.1,,,,,,,MYO1B_RAT,Rattus norvegicus (Rat),actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892] comp118054_c1_seq1,693,50.3608,0.54897939,15,15,,,,,,,,,8.00E-22,CHOYP_MTSS1.1.1.1,,,,,,,,, comp118062_c0_seq1,873,43.7572,0.60855114,18,94,,5.00E-78,Q8NC96,Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1),Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1),GO:0030125; GO:0005905; GO:0006897; GO:0005886; GO:0015031,clathrin vesicle coat; coated pit; endocytosis; plasma membrane; protein transport,PF07933;,6.00E-50,CHOYP_BRAFLDRAFT_72035.1.1,,,,,,,NECP1_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; protein transport [GO:0015031] comp118077_c0_seq1,925,45.5135,0.62697555,21,56,,2.00E-24,O44252,Protein rolling stone,Protein rolling stone,GO:0016021; GO:0016020; GO:0007520; GO:0007519,integral to membrane; membrane; myoblast fusion; skeletal muscle tissue development,,,,,,,,,,ROST_DROME,Drosophila melanogaster (Fruit fly),myoblast fusion [GO:0007520]; skeletal muscle tissue development [GO:0007519] comp118087_c0_seq1,473,48.6258,1.18419789,4,56,,5.00E-14,P21369,Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase),Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase),GO:0008936; GO:0019363,nicotinamidase activity; pyridine nucleotide biosynthetic process,PF00857;,,,,,,,,,PNCA_ECOLI,Escherichia coli (strain K12),NAD metabolic process [GO:0019674]; nicotinamide metabolic process [GO:0006769]; pyridine nucleotide biosynthetic process [GO:0019363] comp118091_c0_seq1,518,47.4903,0.58457781,21,35,,2.00E-99,Q6DF08,UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1),UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1),GO:0032580; GO:0033320; GO:0048040; GO:0050662; GO:0016021,Golgi cisterna membrane; UDP-D-xylose biosynthetic process; UDP-glucuronate decarboxylase activity; coenzyme binding; integral to membrane,PF16363;PF11803;,2.00E-116,CHOYP_UXS1.1.1,,,,,,,UXS1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),UDP-D-xylose biosynthetic process [GO:0033320] comp118094_c0_seq1,1496,42.3128,0.36017339,127,5,,3.00E-28,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp118094_c0_seq2,748,40.7754,0.3220957,2,10,,5.00E-08,Q4GZT3,Polycystin-2 (Polycystic kidney disease 2 protein homolog),Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2),GO:0007259; GO:0035904; GO:0045180; GO:0009925; GO:0001658; GO:0005262; GO:0005509; GO:0048763; GO:0007050; GO:0005911; GO:0071498; GO:0071464; GO:0071470; GO:0042994; GO:0050982; GO:0003127; GO:0071910; GO:0001892; GO:0031941; GO:0001947; GO:0071458; GO:0071556; GO:0005887; GO:0030027; GO:0016020; GO:0072177; GO:0072284; GO:0072218; GO:0072214; GO:0072219; GO:0072235; GO:0072075; GO:0035502; GO:0072208; GO:0005932; GO:0072686; GO:0031512; GO:2000134; GO:0060315; GO:0021915; GO:0031513; GO:0060674; GO:0002133; GO:0071158; GO:0031659; GO:0031587; GO:0045429; GO:0045944; GO:0005267; GO:0030814; GO:0090279; GO:0042127; GO:0051209; GO:0061441; GO:0061333; GO:0021510; GO:0005245; GO:0005248,"JAK-STAT cascade; aorta development; basal cortex; basal plasma membrane; branching involved in ureteric bud morphogenesis; calcium channel activity; calcium ion binding; calcium-induced calcium release activity; cell cycle arrest; cell-cell junction; cellular response to fluid shear stress; cellular response to hydrostatic pressure; cellular response to osmotic stress; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; detection of nodal flow; determination of liver left/right asymmetry; embryonic placenta development; filamentous actin; heart looping; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; lamellipodium; membrane; mesonephric duct development; metanephric S-shaped body morphogenesis; metanephric ascending thin limb development; metanephric cortex development; metanephric cortical collecting duct development; metanephric distal tubule development; metanephric mesenchyme development; metanephric part of ureteric bud development; metanephric smooth muscle tissue development; microtubule basal body; mitotic spindle; motile primary cilium; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of ryanodine-sensitive calcium-release channel activity; neural tube development; nonmotile primary cilium; placenta blood vessel development; polycystin complex; positive regulation of cell cycle arrest; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of nitric oxide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; potassium channel activity; regulation of cAMP metabolic process; regulation of calcium ion import; regulation of cell proliferation; release of sequestered calcium ion into cytosol; renal artery morphogenesis; renal tubule morphogenesis; spinal cord development; voltage-gated calcium channel activity; voltage-gated sodium channel activity",PF08016;,,,,,,,,,PKD2_BOVIN,Bos taurus (Bovine),"aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]" comp118095_c1_seq1,1376,37.064,0.51107289,70,41,,1.00E-13,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp118104_c1_seq1,639,43.349,0.60150523,7,74,,2.00E-24,Q08DJ5,Cadherin-18,Cadherin-18,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;,,,,,,,,,CAD18_BOVIN,Bos taurus (Bovine),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp118104_c2_seq1,707,43.5644,0.68767029,13,39,,2.00E-60,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp118110_c0_seq2,2453,44.843,0.50457163,64,52,,3.00E-115,A9X1A0,Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67),Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67),GO:0004430; GO:0005524; GO:0005794; GO:0005741; GO:0006661; GO:0048015; GO:0030867,1-phosphatidylinositol 4-kinase activity; ATP binding; Golgi apparatus; mitochondrial outer membrane; phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling; rough endoplasmic reticulum membrane,PF00454;,2.00E-93,CHOYP_PI4KB.1.1,,,,,,,PI4KB_PAPAN,Papio anubis (Olive baboon),phosphatidylinositol-mediated signaling [GO:0048015] comp118110_c1_seq1,308,47.0779,0.70575544,4,26,,4.00E-26,Q10366,Phosphatidylinositol 4-kinase pik1 (PI4-kinase) (PtdIns-4-kinase) (EC 2.7.1.67),Phosphatidylinositol 4-kinase pik1 (PI4-kinase) (PtdIns-4-kinase) (EC 2.7.1.67),GO:0004430; GO:0005794; GO:0034613; GO:0005634; GO:0006661; GO:0048015,1-phosphatidylinositol 4-kinase activity; Golgi apparatus; cellular protein localization; nucleus; phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling,PF00454;PF11522;,6.00E-45,CHOYP_PI4KB.1.1,,,,,,,YDBG_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165] comp118114_c1_seq1,424,41.5094,0.71800269,9,26,,2.00E-22,Q8NFR7,Coiled-coil domain-containing protein 148,Coiled-coil domain-containing protein 148,,,,,,,,,,,,CC148_HUMAN,Homo sapiens (Human), comp118121_c0_seq1,357,59.944,1.03197875,1,28,,2.00E-36,Q6A7V2,50S ribosomal protein L35,50S ribosomal protein L35,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01632;,,,,,,,,,RL35_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),translation [GO:0006412] comp118123_c1_seq1,735,42.7211,0.63013815,25,26,,4.00E-94,Q8N5J2,Protein FAM63A,Protein FAM63A,,,PF04424;,1.00E-38,CHOYP_FA63B.1.1,,,,,,,FA63A_HUMAN,Homo sapiens (Human), comp118132_c0_seq1,398,38.4422,1.09880212,0,11,,,,,,,,,,,3.00E-22,ruditapes_c34357,,,,,,, comp118132_c0_seq2,852,44.2488,0.93657224,102,844,,2.00E-32,P41366,Vitelline membrane outer layer protein 1 (VMO-1) (VMO-I) (VMOI),Vitelline membrane outer layer protein 1 (VMO-1) (VMO-I) (VMOI),GO:0005576; GO:0030704,extracellular region; vitelline membrane formation,PF03762;,,,2.00E-21,ruditapes2_c6763,,,,,VMO1_CHICK,Gallus gallus (Chicken), comp118148_c0_seq1,1656,41.1836,0.47554916,113,82,,5.00E-163,Q6GR10,Macrophage erythroblast attacher,Macrophage erythroblast attacher,GO:0007049; GO:0051301; GO:0005737; GO:0005856; GO:0043249; GO:0016363; GO:0005886,cell cycle; cell division; cytoplasm; cytoskeleton; erythrocyte maturation; nuclear matrix; plasma membrane,PF10607;,9.00E-115,CHOYP_LOC100373339.1.1,,,,,,,MAEA_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301]; erythrocyte maturation [GO:0043249] comp118155_c0_seq1,285,35.0877,1.26296216,0,9,,3.00E-16,P51590,Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3),Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2J3_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369] comp118155_c1_seq1,691,31.259,1.13345065,6,96,,7.00E-09,P11714,Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9) (Cytochrome P450-16-alpha) (Cytochrome P450CA) (Testosterone 16-alpha hydroxylase),Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9) (Cytochrome P450-16-alpha) (Cytochrome P450CA) (Testosterone 16-alpha hydroxylase),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2D9_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369] comp118175_c0_seq1,1441,38.4455,0.49264189,111,225,,4.00E-78,Q9H0C8,Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16),Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16),GO:0005737; GO:0046872; GO:0045786; GO:0006470; GO:0004722,cytoplasm; metal ion binding; negative regulation of cell cycle; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,ILKAP_HUMAN,Homo sapiens (Human), comp118175_c0_seq2,606,42.9043,0.57586647,0,0,,3.00E-24,P49595,Probable protein phosphatase 2C F42G9.1 (PP2C) (EC 3.1.3.16),Probable protein phosphatase 2C F42G9.1 (PP2C) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,PP2C1_CAEEL,Caenorhabditis elegans, comp118196_c0_seq1,525,45.5238,0.43147062,24,32,,4.00E-45,Q03468,DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),GO:0005524; GO:0003677; GO:0008094; GO:0007256; GO:0007257; GO:0006284; GO:0003682; GO:0004386; GO:0008630; GO:0035264; GO:0005730; GO:0045494; GO:0032786; GO:0032403; GO:0006290; GO:0009411; GO:0010224; GO:0010165; GO:0010332; GO:0006979; GO:0000303; GO:0009636; GO:0008023; GO:0006366; GO:0006283,"ATP binding; DNA binding; DNA-dependent ATPase activity; activation of JNKK activity; activation of JUN kinase activity; base-excision repair; chromatin binding; helicase activity; intrinsic apoptotic signaling pathway in response to DNA damage; multicellular organism growth; nucleolus; photoreceptor cell maintenance; positive regulation of DNA-dependent transcription, elongation; protein complex binding; pyrimidine dimer repair; response to UV; response to UV-B; response to X-ray; response to gamma radiation; response to oxidative stress; response to superoxide; response to toxic substance; transcription elongation factor complex; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF00271;PF00176;,2.00E-21,CHOYP_ERCC6.1.1,,,,,,,ERCC6_HUMAN,Homo sapiens (Human),"activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]" comp118203_c0_seq1,587,47.8705,0.38984201,0,0,,,,,,,,,2.00E-21,CHOYP_AGAP_AGAP010490.1.1,,,,,,,,, comp118203_c0_seq2,1129,46.8556,0.53402688,47,8,,5.00E-115,Q8BPN8,DmX-like protein 2 (Rabconnectin-3),DmX-like protein 2 (Rabconnectin-3),GO:0030054; GO:0030672,cell junction; synaptic vesicle membrane,PF12234;PF00400;,6.00E-64,CHOYP_AGAP_AGAP010490.1.1,,,,,,,DMXL2_MOUSE,Mus musculus (Mouse), comp118204_c1_seq1,351,62.3932,1.02134299,0,25,,4.00E-10,P0CI75,Bifunctional protein BirA [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)],Bifunctional ligase/repressor BirA (Biotin--[acetyl-CoA-carboxylase] ligase) (EC 6.3.4.15) (Biotin--protein ligase) (Biotin-[acetyl-CoA carboxylase] synthetase),GO:0005524; GO:0003677; GO:0004077; GO:0006464; GO:0006355; GO:0006351,"ATP binding; DNA binding; biotin-[acetyl-CoA-carboxylase] ligase activity; cellular protein modification process; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02237;PF03099;PF08279;,,,,,,,,,BIRA_BACSU,Bacillus subtilis (strain 168),"protein biotinylation [GO:0009305]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp118206_c0_seq1,553,43.9421,0.45163191,16,14,,,,,,,,,9.00E-52,CHOYP_LOC579391.1.1,,,,,,,,, comp118207_c0_seq2,491,34.0122,0.49440343,0,19,,2.00E-08,P49711,Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog),Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog),GO:0043035; GO:0016568; GO:0007059; GO:0000775; GO:0000793; GO:0010216; GO:0045892; GO:0005730; GO:0005654; GO:0016584; GO:0045893; GO:0070602; GO:0006349; GO:0040029; GO:0035065; GO:0031060; GO:0040030; GO:0043565; GO:0003700; GO:0003714; GO:0044212; GO:0006351; GO:0008270,"chromatin insulator sequence binding; chromatin modification; chromosome segregation; chromosome, centromeric region; condensed chromosome; maintenance of DNA methylation; negative regulation of transcription, DNA-dependent; nucleolus; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; regulation of centromeric sister chromatid cohesion; regulation of gene expression by genetic imprinting; regulation of gene expression, epigenetic; regulation of histone acetylation; regulation of histone methylation; regulation of molecular function, epigenetic; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; transcription regulatory region DNA binding; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,CTCF_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; chromosome segregation [GO:0007059]; DNA methylation [GO:0006306]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome positioning [GO:0016584]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of centromeric sister chromatid cohesion [GO:0070602]; regulation of gene expression, epigenetic [GO:0040029]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of histone acetylation [GO:0035065]; regulation of histone methylation [GO:0031060]; regulation of molecular function, epigenetic [GO:0040030]" comp118213_c0_seq2,876,36.5297,0.31069951,27,94,,2.00E-45,Q9BXW4,Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma),Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma),GO:0005776; GO:0000421; GO:0006914; GO:0031410; GO:0012505; GO:0005874; GO:0031090,autophagic vacuole; autophagic vacuole membrane; autophagy; cytoplasmic vesicle; endomembrane system; microtubule; organelle membrane,PF02991;,7.00E-75,CHOYP_LOC100367880.1.1,,,,,,,MLP3C_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; mitophagy [GO:0000422] comp118214_c0_seq1,767,43.807,1.03151039,20,30,,7.00E-32,P30771,ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1),ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1),GO:0005524; GO:0004004; GO:0003677; GO:0030466; GO:0005737; GO:0008298; GO:0070478; GO:0003676; GO:0005634; GO:0005844; GO:0016567; GO:0006449; GO:0043024; GO:0008270,"ATP binding; ATP-dependent RNA helicase activity; DNA binding; chromatin silencing at silent mating-type cassette; cytoplasm; intracellular mRNA localization; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; nucleic acid binding; nucleus; polysome; protein ubiquitination; regulation of translational termination; ribosomal small subunit binding; zinc ion binding",PF09416;,,,,,,,,,NAM7_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"chromatin silencing at silent mating-type cassette [GO:0030466]; DNA recombination [GO:0006310]; intracellular mRNA localization [GO:0008298]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein ubiquitination [GO:0016567]; regulation of translational termination [GO:0006449]" comp118214_c1_seq1,667,38.2309,1.04606786,0,0,,9.00E-11,Q8R151,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,,,,,,,,,ZNFX1_MOUSE,Mus musculus (Mouse), comp118214_c1_seq2,801,39.3258,1.00518205,9,9,,2.00E-25,Q00416,Helicase SEN1 (EC 3.6.4.-) (tRNA-splicing endonuclease positive effector),Helicase SEN1 (EC 3.6.4.-) (tRNA-splicing endonuclease positive effector),GO:0005524; GO:0043141; GO:0032575; GO:0035649; GO:0006378; GO:0045005; GO:0005634; GO:0019904; GO:0006364; GO:0005657; GO:0016180; GO:0031126; GO:0008033; GO:0006369,ATP binding; ATP-dependent 5'-3' DNA helicase activity; ATP-dependent 5'-3' RNA helicase activity; Nrd1 complex; mRNA polyadenylation; maintenance of fidelity involved in DNA-dependent DNA replication; nucleus; protein domain specific binding; rRNA processing; replication fork; snRNA processing; snoRNA 3'-end processing; tRNA processing; termination of RNA polymerase II transcription,PF12726;,,,,,,,,,SEN1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA-dependent DNA replication maintenance of fidelity [GO:0045005]; DNA-templated transcription, termination [GO:0006353]; mRNA 3'-end processing [GO:0031124]; mRNA polyadenylation [GO:0006378]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; rRNA processing [GO:0006364]; snoRNA 3'-end processing [GO:0031126]; snRNA processing [GO:0016180]; termination of RNA polymerase II transcription [GO:0006369]; tRNA processing [GO:0008033]" comp118219_c1_seq1,371,45.8221,0.52365245,13,13,,5.00E-27,A6BM72,Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11),Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11),GO:0016323; GO:0034109; GO:0016021; GO:0010842,basolateral plasma membrane; homotypic cell-cell adhesion; integral to membrane; retina layer formation,PF12661;PF00053;,,,,,,,,,MEG11_HUMAN,Homo sapiens (Human),homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842] comp118231_c0_seq1,202,25.7426,0,15,11,,,,,,,,,,,5.00E-16,ruditapes_c27972,,,,,,, comp118233_c0_seq2,750,41.3333,0.87540225,11,71,,2.00E-25,Q16832,"Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)","Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)",GO:0005524; GO:0031214; GO:0007155; GO:0035988; GO:0005518; GO:0030199; GO:0003416; GO:0005887; GO:0001503; GO:0090091; GO:0010763; GO:0048146; GO:0045669; GO:0045860; GO:0051091; GO:0046777; GO:0038062; GO:0030500,ATP binding; biomineral tissue development; cell adhesion; chondrocyte proliferation; collagen binding; collagen fibril organization; endochondral bone growth; integral to plasma membrane; ossification; positive regulation of extracellular matrix disassembly; positive regulation of fibroblast migration; positive regulation of fibroblast proliferation; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; positive regulation of sequence-specific DNA binding transcription factor activity; protein autophosphorylation; protein tyrosine kinase collagen receptor activity; regulation of bone mineralization,PF00754;PF07714;,,,,,,,,,DDR2_HUMAN,Homo sapiens (Human),biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; signal transduction [GO:0007165] comp118236_c0_seq1,1197,41.6876,0.50523961,36,134,,3.00E-86,Q06136,3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1),3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1),GO:0047560; GO:0006666; GO:0005789; GO:0005615; GO:0016021; GO:0030148,3-dehydrosphinganine reductase activity; 3-keto-sphinganine metabolic process; endoplasmic reticulum membrane; extracellular space; integral to membrane; sphingolipid biosynthetic process,PF00106;,,,,,,,,,KDSR_HUMAN,Homo sapiens (Human),3-keto-sphinganine metabolic process [GO:0006666]; sphingolipid biosynthetic process [GO:0030148] comp118238_c0_seq2,1211,46.4079,0.93632283,0,0,,1.00E-122,P49869,Probable nuclear hormone receptor HR38 (dHR38) (Nuclear receptor subfamily 4 group A member 4),Probable nuclear hormone receptor HR38 (dHR38) (Nuclear receptor subfamily 4 group A member 4),GO:0000977; GO:0042335; GO:0004879; GO:0005634; GO:0006909; GO:0048082; GO:0003707; GO:0008270,RNA polymerase II regulatory region sequence-specific DNA binding; cuticle development; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; phagocytosis; regulation of adult chitin-containing cuticle pigmentation; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,9.00E-88,CHOYP_LOC100373323.1.1,,,,,,,HR38_DROME,Drosophila melanogaster (Fruit fly),"cuticle development [GO:0042335]; epidermis development [GO:0008544]; phagocytosis [GO:0006909]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of adult chitin-containing cuticle pigmentation [GO:0048082]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]" comp118238_c0_seq5,1321,46.4799,0.89774575,0,0,,1.00E-117,Q06219,Nuclear receptor subfamily 4 group A member 2 (NUR-related factor 1) (Orphan nuclear receptor NURR1),Nuclear receptor subfamily 4 group A member 2 (NUR-related factor 1) (Orphan nuclear receptor NURR1),GO:0008344; GO:0031668; GO:0034599; GO:0021952; GO:0005737; GO:0016265; GO:0042416; GO:0071542; GO:0051866; GO:0021986; GO:0004879; GO:0043524; GO:0042551; GO:0001764; GO:0005634; GO:0043085; GO:0045944; GO:0009791; GO:0042053; GO:0043576; GO:0001975; GO:0001666; GO:0010035; GO:0017085; GO:0043565; GO:0003707; GO:0008270,adult locomotory behavior; cellular response to extracellular stimulus; cellular response to oxidative stress; central nervous system projection neuron axonogenesis; cytoplasm; death; dopamine biosynthetic process; dopaminergic neuron differentiation; general adaptation syndrome; habenula development; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; negative regulation of neuron apoptotic process; neuron maturation; neuron migration; nucleus; positive regulation of catalytic activity; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; regulation of dopamine metabolic process; regulation of respiratory gaseous exchange; response to amphetamine; response to hypoxia; response to inorganic substance; response to insecticide; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR4A2_MOUSE,Mus musculus (Mouse),"adult locomotory behavior [GO:0008344]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; cellular response to extracellular stimulus [GO:0031668]; cellular response to oxidative stress [GO:0034599]; central nervous system neuron differentiation [GO:0021953]; central nervous system projection neuron axonogenesis [GO:0021952]; dopamine biosynthetic process [GO:0042416]; dopamine metabolic process [GO:0042417]; dopaminergic neuron differentiation [GO:0071542]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; general adaptation syndrome [GO:0051866]; habenula development [GO:0021986]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron migration [GO:0001764]; positive regulation of catalytic activity [GO:0043085]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to insecticide [GO:0017085]; transcription, DNA-templated [GO:0006351]" comp118238_c0_seq6,905,49.6133,0.95296616,0,0,,2.00E-24,P28701,Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma),Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF11825;PF00105;,2.00E-68,CHOYP_LOC100373323.1.1,,,,,,,RXRG_CHICK,Gallus gallus (Chicken),"transcription, DNA-templated [GO:0006351]" comp118249_c0_seq1,657,39.2694,0.79893337,110,330,,6.00E-15,D9HP19,Cell number regulator 3 (ZmCNR03),Cell number regulator 3 (ZmCNR03),GO:0016021,integral to membrane,PF04749;,,,2.00E-59,ruditapes_lrc32392,,,,,CNR3_MAIZE,Zea mays (Maize), comp118250_c0_seq1,273,45.4212,0.43492647,3,0,,,,,,,,,4.00E-21,CHOYP_LOC100371489.2.2,,,,,,,,, comp118271_c0_seq1,811,48.0888,0.62059972,11,88,,2.00E-07,Q5SZI1,Low-density lipoprotein receptor class A domain-containing protein 2,Low-density lipoprotein receptor class A domain-containing protein 2,GO:0016021,integral to membrane,PF00057;,,,,,,,,,LRAD2_HUMAN,Homo sapiens (Human), comp118274_c0_seq1,382,41.8848,0.24073075,14,26,,1.00E-17,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp118285_c0_seq1,536,42.5373,0.24822891,10,15,,2.00E-24,Q5HZI9,Solute carrier family 25 member 51 (Mitochondrial carrier triple repeat protein 1),Solute carrier family 25 member 51 (Mitochondrial carrier triple repeat protein 1),GO:0016021; GO:0005743; GO:0005739; GO:0006810,integral to membrane; mitochondrial inner membrane; mitochondrion; transport,PF00153;,,,,,,,,,S2551_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transport [GO:0006810] comp118296_c0_seq1,234,50.8547,1.0657791,3,6,,1.00E-14,Q9P215,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,,,,,,,,,POGK_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp118318_c0_seq1,711,47.398,0.84853906,63,24,,1.00E-59,P48067,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),GO:0015375; GO:0005887; GO:0005328,glycine:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,1.00E-32,CHOYP_SC6A5.4.7,,,,,,,SC6A9_HUMAN,Homo sapiens (Human),"glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp118342_c0_seq1,560,47.1429,0.7103332,3,22,,8.00E-19,Q8VHK1,Caskin-2,Caskin-2,GO:0005737,cytoplasm,PF12796;PF16632;PF00536;PF07653;,,,,,,,,,CSKI2_MOUSE,Mus musculus (Mouse),signal transduction [GO:0007165] comp118342_c0_seq2,552,53.0797,0.64416389,9,0,,,,,,,,,5.00E-68,CHOYP_CSKI2.1.1,,,,,,,,, comp118342_c1_seq1,507,47.14,0.46253157,12,7,,6.00E-23,Q8VHK2,Caskin-1 (CASK-interacting protein 1),Caskin-1 (CASK-interacting protein 1),GO:0005737; GO:0019904; GO:0007165,cytoplasm; protein domain specific binding; signal transduction,PF12796;PF16632;PF00536;PF07653;,,,,,,,,,CSKI1_RAT,Rattus norvegicus (Rat),signal transduction [GO:0007165] comp118346_c0_seq1,1191,48.2788,0.60599941,76,0,,8.00E-08,Q93075,Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),GO:0006987; GO:0044267; GO:0016888; GO:0046872; GO:0090305; GO:0005654,"activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleoplasm",PF01026;,,,,,,,,,TATD2_HUMAN,Homo sapiens (Human),DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498] comp118353_c0_seq1,610,30.9836,0.55082411,27,35,,7.00E-15,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,1.00E-12,CHOYP_LOC100892427.2.2,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp118363_c0_seq1,1682,34.1855,0.71594415,37,808,,3.00E-08,O35778,Natural killer cells antigen CD94 (Killer cell lectin-like receptor subfamily D member 1) (CD antigen CD94),Natural killer cells antigen CD94 (Killer cell lectin-like receptor subfamily D member 1) (CD antigen CD94),GO:0030246; GO:0009897; GO:0016021,carbohydrate binding; external side of plasma membrane; integral to membrane,PF00059;,,,,,,,,,KLRD1_RAT,Rattus norvegicus (Rat),natural killer cell mediated immunity [GO:0002228] comp118365_c0_seq1,405,44.6914,0.64539401,2,44,,1.00E-08,Q8BG19,Transmembrane and TPR repeat-containing protein 4,Transmembrane and TPR repeat-containing protein 4,GO:0016021,integral to membrane,PF08409;PF00515;PF13181;,,,,,,,,,TMTC4_MOUSE,Mus musculus (Mouse), comp118365_c1_seq1,445,45.618,0.47622061,1,60,,2.00E-38,Q6DCD5,Transmembrane and TPR repeat-containing protein 2,Transmembrane and TPR repeat-containing protein 2,GO:0016021,integral to membrane,PF08409;PF00515;PF13181;,,,,,,,,,TMTC2_XENLA,Xenopus laevis (African clawed frog), comp118366_c1_seq1,436,43.8073,0.71922696,0,52,,1.00E-06,O08710,Thyroglobulin (Tg),Thyroglobulin (Tg),GO:0005576; GO:0005615; GO:0042446; GO:0015705; GO:0031641; GO:0030878; GO:0006590,extracellular region; extracellular space; hormone biosynthetic process; iodide transport; regulation of myelination; thyroid gland development; thyroid hormone generation,PF00135;PF07699;PF00086;,,,,,,,,,THYG_MOUSE,Mus musculus (Mouse),hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; thyroid hormone metabolic process [GO:0042403]; transcytosis [GO:0045056] comp118375_c0_seq1,791,45.2592,0.54395691,26,32,,6.00E-71,O42127,Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1),Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1),GO:0005524; GO:0006915; GO:0005007; GO:0016021; GO:0018108; GO:0005886; GO:0008284; GO:0001501,ATP binding; apoptotic process; fibroblast growth factor-activated receptor activity; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of cell proliferation; skeletal system development,PF07679;PF07714;,1.00E-32,CHOYP_FGFR2.3.3,,,,,,,FGFR3_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915]; positive regulation of cell proliferation [GO:0008284]; skeletal system development [GO:0001501] comp118382_c0_seq1,961,44.1207,0.86108221,0,0,,2.00E-30,Q9EPT5,Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2),Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2),GO:0005887; GO:0015132,integral to plasma membrane; prostaglandin transmembrane transporter activity,PF07648;PF03137;,,,,,,,,,SO2A1_MOUSE,Mus musculus (Mouse),prostaglandin transport [GO:0015732]; sodium-independent organic anion transport [GO:0043252] comp118385_c2_seq1,1039,36.4774,0.46833705,79,484,,4.00E-54,Q8NBA8,DTW domain-containing protein 2,DTW domain-containing protein 2,,,PF03942;,,,,,,,,,DTWD2_HUMAN,Homo sapiens (Human),positive regulation of protein targeting to mitochondrion [GO:1903955] comp118389_c0_seq1,267,44.9438,0.29778195,2,0,,1.00E-08,P41731,CD63 antigen (CD antigen CD63),CD63 antigen (CD antigen CD63),GO:0009986; GO:0034613; GO:0010008; GO:0016021; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0005886; GO:2000680,cell surface; cellular protein localization; endosome membrane; integral to membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; plasma membrane; regulation of rubidium ion transport,PF00335;,,,,,,,,,CD63_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular protein localization [GO:0034613]; endosome to melanosome transport [GO:0035646]; epithelial cell differentiation [GO:0030855]; negative regulation of epithelial cell migration [GO:0010633]; pigmentation [GO:0043473]; pigment cell differentiation [GO:0050931]; pigment granule maturation [GO:0048757]; positive regulation of cell adhesion [GO:0045785]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of rubidium ion transport [GO:2000680]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] comp118389_c2_seq1,494,36.6397,0.36757576,22,20,,4.00E-20,P48509,CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151),CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151),GO:0042098; GO:0007155; GO:0016477; GO:0005829; GO:0030198; GO:0031581; GO:0005887,T cell proliferation; cell adhesion; cell migration; cytosol; extracellular matrix organization; hemidesmosome assembly; integral to plasma membrane,PF00335;,9.00E-26,CHOYP_PHUM_PHUM503620.1.1,,,,,,,CD151_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; hemidesmosome assembly [GO:0031581]; T cell proliferation [GO:0042098] comp118391_c0_seq1,1028,45.7198,0.49045858,50,43,,2.00E-92,Q9JLN9,Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),GO:0005524; GO:0000139; GO:0016605; GO:0001030; GO:0001031; GO:0001032; GO:0031929; GO:0031931; GO:0031932; GO:0071456; GO:0031669; GO:0005829; GO:0008144; GO:0005789; GO:0007281; GO:0005764; GO:0070438; GO:0005741; GO:0051534; GO:0045792; GO:0016242; GO:0005634; GO:0018105; GO:0018107; GO:0030838; GO:0001938; GO:0010592; GO:0046889; GO:0010831; GO:0050731; GO:0051897; GO:0051496; GO:0045945; GO:0045727; GO:0046777; GO:0004674; GO:0032314; GO:0043610; GO:0031998; GO:0005979; GO:0045859; GO:0032095; GO:0043200; GO:0032868; GO:0043022; GO:0031529,ATP binding; Golgi membrane; PML body; RNA polymerase III type 1 promoter DNA binding; RNA polymerase III type 2 promoter DNA binding; RNA polymerase III type 3 promoter DNA binding; TOR signaling cascade; TORC1 complex; TORC2 complex; cellular response to hypoxia; cellular response to nutrient levels; cytosol; drug binding; endoplasmic reticulum membrane; germ cell development; lysosome; mTOR-FKBP12-rapamycin complex; mitochondrial outer membrane; negative regulation of NFAT protein import into nucleus; negative regulation of cell size; negative regulation of macroautophagy; nucleus; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; positive regulation of lamellipodium assembly; positive regulation of lipid biosynthetic process; positive regulation of myotube differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase III promoter; positive regulation of translation; protein autophosphorylation; protein serine/threonine kinase activity; regulation of Rac GTPase activity; regulation of carbohydrate utilization; regulation of fatty acid beta-oxidation; regulation of glycogen biosynthetic process; regulation of protein kinase activity; regulation of response to food; response to amino acid stimulus; response to insulin stimulus; ribosome binding; ruffle organization,PF11865;PF02259;PF02260;PF00454;PF08771;,3.00E-74,CHOYP_MTOR.2.2,,,,,,,MTOR_MOUSE,Mus musculus (Mouse),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] comp118391_c1_seq1,404,47.5248,0.58196444,15,2,,6.00E-27,Q9VK45,Target of rapamycin (EC 2.7.1.-),Target of rapamycin (EC 2.7.1.-),GO:0005524; GO:0007411; GO:0007049; GO:0048813; GO:0009594; GO:0008340; GO:0008144; GO:0032456; GO:0008406; GO:0035264; GO:0016242; GO:0042331; GO:0030307; GO:0045793; GO:0040018; GO:0046622; GO:0001934; GO:0090070; GO:0004672; GO:0043621; GO:2000377; GO:0006974; GO:0051124,ATP binding; axon guidance; cell cycle; dendrite morphogenesis; detection of nutrient; determination of adult lifespan; drug binding; endocytic recycling; gonad development; multicellular organism growth; negative regulation of macroautophagy; phototaxis; positive regulation of cell growth; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; positive regulation of protein phosphorylation; positive regulation of ribosome biogenesis; protein kinase activity; protein self-association; regulation of reactive oxygen species metabolic process; response to DNA damage stimulus; synaptic growth at neuromuscular junction,PF11865;PF02259;PF02260;PF00454;PF08771;,,,,,,,,,TOR_DROME,Drosophila melanogaster (Fruit fly),"apical protein localization [GO:0045176]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; dendrite morphogenesis [GO:0048813]; detection of nutrient [GO:0009594]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; endocytic recycling [GO:0032456]; germarium-derived cystoblast division [GO:0048142]; gonad development [GO:0008406]; growth [GO:0040007]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of macroautophagy [GO:0016242]; phosphorylation [GO:0016310]; phototaxis [GO:0042331]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ribosome biogenesis [GO:0090070]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of response to drug [GO:2001023]; regulation of terminal button organization [GO:2000331]; response to nutrient [GO:0007584]; somatic muscle development [GO:0007525]; synaptic growth at neuromuscular junction [GO:0051124]; terminal branching, open tracheal system [GO:0007430]" comp118427_c0_seq1,252,42.4603,0.53040668,4,15,,2.00E-10,P55285,Cadherin-6 (Kidney cadherin) (K-cadherin),Cadherin-6 (Kidney cadherin) (K-cadherin),GO:0034332; GO:0005509; GO:0007155; GO:0034329; GO:0005737; GO:0007156; GO:0016021; GO:0005634; GO:0005886,adherens junction organization; calcium ion binding; cell adhesion; cell junction assembly; cytoplasm; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF01049;,,,,,,,,,CADH6_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219] comp118427_c1_seq1,353,44.4759,0.63503445,2,17,,2.00E-27,Q8BNA6,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_MOUSE,Mus musculus (Mouse),cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842] comp118442_c0_seq1,507,40.2367,0.78312281,0,58,,2.00E-08,Q28DL4,TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),GO:0050852; GO:0007250; GO:0046849; GO:0048468; GO:0005737; GO:0070498; GO:0009887; GO:0001503; GO:0043123; GO:0043507; GO:0031666; GO:0045672; GO:0070534; GO:0051865; GO:0042981; GO:0004871; GO:0004842; GO:0008270,T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; bone remodeling; cell development; cytoplasm; interleukin-1-mediated signaling pathway; organ morphogenesis; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of osteoclast differentiation; protein K63-linked ubiquitination; protein autoubiquitination; regulation of apoptotic process; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,TRAF6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),immune response [GO:0006955]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165] comp118442_c1_seq1,370,43.2432,0.35132832,0,30,,2.00E-10,Q55A66,TNF receptor-associated factor family protein DDB_G0272098,TNF receptor-associated factor family protein DDB_G0272098,GO:0005737; GO:0008270,cytoplasm; zinc ion binding,PF02176;,,,,,,,,,Y2098_DICDI,Dictyostelium discoideum (Slime mold), comp118445_c1_seq1,628,49.5223,0.65146408,31,29,,2.00E-25,Q64512,Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),GO:0005737; GO:0005856; GO:0030027; GO:0005634; GO:0004725,cytoplasm; cytoskeleton; lamellipodium; nucleus; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,6.00E-17,CHOYP_LOC100537667.1.1,,,,,,,PTN13_MOUSE,Mus musculus (Mouse),peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp118459_c1_seq1,615,45.0407,0.25936911,30,6,,2.00E-97,Q9VT28,Protein furry,Protein furry,GO:0048800; GO:0045177; GO:0005938; GO:0008407; GO:0070593; GO:0035317; GO:0048601; GO:0045860; GO:0045893; GO:0048814; GO:0042052; GO:0006351,"antennal morphogenesis; apical part of cell; cell cortex; chaeta morphogenesis; dendrite self-avoidance; imaginal disc-derived wing hair organization; oocyte morphogenesis; positive regulation of protein kinase activity; positive regulation of transcription, DNA-dependent; regulation of dendrite morphogenesis; rhabdomere development; transcription, DNA-dependent",PF14225;PF14228;PF14222;,3.00E-90,CHOYP_LOC657755.1.1,,,,,,,FRY_DROME,Drosophila melanogaster (Fruit fly),"actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]" comp118459_c1_seq2,226,43.3628,0.28375556,0,0,,,,,,,,,9.00E-28,CHOYP_LOC657755.1.1,,,,,,,,, comp118462_c2_seq2,255,39.2157,0.3091835,2,21,,1.00E-07,Q8N9L9,Acyl-coenzyme A thioesterase 4 (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib),Acyl-coenzyme A thioesterase 4 (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib),GO:0047617; GO:0004091; GO:0043649; GO:0001676; GO:0016290; GO:0005777; GO:0032788; GO:0046459; GO:0004778; GO:0006104; GO:0032789; GO:0000038,acyl-CoA hydrolase activity; carboxylesterase activity; dicarboxylic acid catabolic process; long-chain fatty acid metabolic process; palmitoyl-CoA hydrolase activity; peroxisome; saturated monocarboxylic acid metabolic process; short-chain fatty acid metabolic process; succinyl-CoA hydrolase activity; succinyl-CoA metabolic process; unsaturated monocarboxylic acid metabolic process; very long-chain fatty acid metabolic process,PF08840;PF04775;,,,,,,,,,ACOT4_HUMAN,Homo sapiens (Human),acyl-CoA metabolic process [GO:0006637]; dicarboxylic acid catabolic process [GO:0043649]; dicarboxylic acid metabolic process [GO:0043648]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; saturated monocarboxylic acid metabolic process [GO:0032788]; short-chain fatty acid metabolic process [GO:0046459]; succinyl-CoA metabolic process [GO:0006104]; unsaturated monocarboxylic acid metabolic process [GO:0032789]; very long-chain fatty acid metabolic process [GO:0000038] comp118468_c0_seq1,239,38.9121,0.11101027,2,22,,,,,,,,,,,3.00E-20,ruditapes_c31033,,,,,,, comp118472_c0_seq1,946,40.3805,0.80125312,40,16,,9.00E-77,P0CE10,"Putative uncharacterized protein At4g01020, chloroplastic","ATP-dependent RNA helicase DEAH11, chloroplastic (EC 3.6.4.13)",GO:0005524; GO:0008026; GO:0003723; GO:0009507; GO:0008270,ATP binding; ATP-dependent helicase activity; RNA binding; chloroplast; zinc ion binding,PF00270;PF04408;PF00271;PF01485;PF07717;PF13445;,1.00E-20,CHOYP_Y4102.1.1,,,,,,,Y4102_ARATH,Arabidopsis thaliana (Mouse-ear cress),RNA processing [GO:0006396] comp118472_c1_seq1,1018,42.0432,0.71508841,37,2,,4.00E-53,Q17R09,Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38),Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38),GO:0005524; GO:0008026; GO:0008380; GO:0006397; GO:0003676; GO:0005681,ATP binding; ATP-dependent helicase activity; RNA splicing; mRNA processing; nucleic acid binding; spliceosomal complex,PF00270;PF04408;PF00271;PF07717;,2.00E-26,CHOYP_LOC100632169.2.6,,,,,,,PRP16_BOVIN,Bos taurus (Bovine),"mRNA splicing, via spliceosome [GO:0000398]" comp118479_c0_seq1,682,40.3226,0.4083161,46,16,,3.00E-07,Q96XY5,Uncharacterized protein STK_23830,Uncharacterized protein STK_23830,,,PF01661;,,,,,,,,,Y2383_SULTO,Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7), comp118482_c0_seq2,445,44.4944,0.43512415,0,14,,3.00E-46,P54098,DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha),DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha),GO:0003677; GO:0006261; GO:0003887; GO:0007568; GO:0006287; GO:0008219; GO:0003682; GO:0004527; GO:0005760; GO:0006264; GO:0005743; GO:0042645,"DNA binding; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; aging; base-excision repair, gap-filling; cell death; chromatin binding; exonuclease activity; gamma DNA polymerase complex; mitochondrial DNA replication; mitochondrial inner membrane; mitochondrial nucleoid",PF00476;,,,6.00E-25,ruditapes_c15844,,,,,DPOG1_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-dependent DNA replication [GO:0006261]; DNA metabolic process [GO:0006259]; mitochondrial DNA replication [GO:0006264]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416]" comp118490_c0_seq2,458,46.5066,0.60864859,14,0,,8.00E-41,Q9V9W8,Protein pygopus (Protein gammy legs),Protein pygopus (Protein gammy legs),GO:0016055; GO:0060232; GO:0048813; GO:0035214; GO:0048526; GO:0005634; GO:0030177; GO:0045944; GO:0007367; GO:0006351; GO:0008270,"Wnt receptor signaling pathway; delamination; dendrite morphogenesis; eye-antennal disc development; imaginal disc-derived wing expansion; nucleus; positive regulation of Wnt receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; segment polarity determination; transcription, DNA-dependent; zinc ion binding",,6.00E-47,CHOYP_LOC100875705.1.1,,,,,,,PYGO_DROME,Drosophila melanogaster (Fruit fly),"delamination [GO:0060232]; dendrite morphogenesis [GO:0048813]; embryonic pattern specification [GO:0009880]; eye-antennal disc development [GO:0035214]; imaginal disc-derived wing expansion [GO:0048526]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; segment polarity determination [GO:0007367]; transcription, DNA-templated [GO:0006351]; wing disc morphogenesis [GO:0007472]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]" comp118491_c0_seq1,832,40.625,0.75804565,23,34,,4.00E-50,Q7TN73,CAS1 domain-containing protein 1,CAS1 domain-containing protein 1,GO:0016021,integral to membrane,PF07779;,6.00E-37,CHOYP_ISCW_ISCW021640.1.1,,,,,,,CASD1_MOUSE,Mus musculus (Mouse), comp118492_c0_seq1,483,48.2402,0.46504264,1,40,,2.00E-28,E1BP74,Meiosis arrest female protein 1 (Limkain-b1),Meiosis arrest female protein 1 (Limkain-b1),GO:0003723; GO:0030154; GO:0007143; GO:0010923; GO:0000166; GO:0048477; GO:0005777; GO:0010468,RNA binding; cell differentiation; female meiosis; negative regulation of phosphatase activity; nucleotide binding; oogenesis; peroxisome; regulation of gene expression,PF11608;PF01936;PF12872;,,,,,,,,,MARF1_BOVIN,Bos taurus (Bovine),double-strand break repair [GO:0006302]; female meiotic division [GO:0007143]; negative regulation of phosphatase activity [GO:0010923]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] comp118492_c1_seq1,254,52.3622,0.41035119,1,26,,,,,,,,,2.00E-24,CHOYP_MARF1.1.1,,,,,,,,, comp118497_c1_seq1,562,41.9929,0.53548604,0,4,,3.00E-09,P22339,Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118),Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118),GO:0000186; GO:0006915; GO:0030154; GO:0007275; GO:0006469; GO:0005634; GO:0051726; GO:0006950,activation of MAPKK activity; apoptotic process; cell differentiation; multicellular organismal development; negative regulation of protein kinase activity; nucleus; regulation of cell cycle; response to stress,PF01248;,,,,,,,,,GA45B_MOUSE,Mus musculus (Mouse),activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950] comp118497_c1_seq2,586,41.6382,0.51858799,2,4,,3.00E-15,Q60GI5,Growth arrest and DNA damage-inducible protein GADD45 alpha,Growth arrest and DNA damage-inducible protein GADD45 alpha,GO:0007050; GO:0071479; GO:0071260; GO:0007098; GO:0001047; GO:0006469; GO:0005634; GO:2000379; GO:0042770,cell cycle arrest; cellular response to ionizing radiation; cellular response to mechanical stimulus; centrosome cycle; core promoter binding; negative regulation of protein kinase activity; nucleus; positive regulation of reactive oxygen species metabolic process; signal transduction in response to DNA damage,PF01248;,,,,,,,,,GA45A_FELCA,Felis catus (Cat) (Felis silvestris catus),cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974] comp118499_c1_seq1,952,45.6933,0.38383474,23,29,,3.00E-07,P53666,LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1),LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1),GO:0005524; GO:0005801; GO:0005737; GO:0005634; GO:0004674; GO:0007283; GO:0008270,ATP binding; cis-Golgi network; cytoplasm; nucleus; protein serine/threonine kinase activity; spermatogenesis; zinc ion binding,PF00412;PF00595;PF07714;,,,,,,,,,LIMK2_CHICK,Gallus gallus (Chicken),spermatogenesis [GO:0007283] comp118503_c0_seq1,615,35.4472,0.15601561,29,24,,9.00E-30,Q3MI05,Lysosomal protective protein (EC 3.4.16.5) (Cathepsin A) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain],Lysosomal protective protein (EC 3.4.16.5) (Cathepsin A) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain],GO:0005764; GO:0005634; GO:0006508; GO:0004185,lysosome; nucleus; proteolysis; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,PPGB_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp118513_c0_seq1,464,48.4914,0.58814502,33,9,,6.00E-66,Q9P217,Zinc finger SWIM domain-containing protein 5,Zinc finger SWIM domain-containing protein 5,GO:0008270,zinc ion binding,,2.00E-66,CHOYP_ZSWM5.1.1,,,,,,,ZSWM5_HUMAN,Homo sapiens (Human), comp118524_c0_seq1,250,42.8,0.96675216,0,37,,7.00E-06,P35821,Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2),Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2),GO:0031532; GO:0005829; GO:0005769; GO:0005789; GO:0030968; GO:0008286; GO:0005886; GO:0035791; GO:0004725; GO:0030100; GO:1902202; GO:0009966; GO:0008270,actin cytoskeleton reorganization; cytosol; early endosome; endoplasmic reticulum membrane; endoplasmic reticulum unfolded protein response; insulin receptor signaling pathway; plasma membrane; platelet-derived growth factor receptor-beta signaling pathway; protein tyrosine phosphatase activity; regulation of endocytosis; regulation of hepatocyte growth factor receptor signaling pathway; regulation of signal transduction; zinc ion binding,PF00102;,,,,,,,,,PTN1_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; endoplasmic reticulum unfolded protein response [GO:0030968]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; response to endoplasmic reticulum stress [GO:0034976] comp118530_c1_seq1,374,41.4439,0.45290179,4,27,,1.00E-25,P47173,Uncharacterized protein YJR142W,Uncharacterized protein YJR142W,GO:0044715,8-oxo-dGDP phosphatase activity,PF15916;PF00293;,,,,,,,,,YJ9J_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp118533_c0_seq1,1023,45.9433,0.90106229,140,533,,5.00E-39,Q9N2D1,Tryptase (EC 3.4.21.59),Tryptase (EC 3.4.21.59),GO:0005576; GO:0006508; GO:0004252,extracellular region; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,TRYT_PIG,Sus scrofa (Pig), comp118535_c0_seq1,1366,45.1684,0.37905018,106,12,,4.00E-58,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,,,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp118539_c0_seq1,744,47.043,0.6728337,13,50,,5.00E-47,Q9D0F3,Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58),Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58),GO:0030134; GO:0006888; GO:0005794; GO:0000139; GO:0007030; GO:0005789; GO:0007029; GO:0005793; GO:0033116; GO:0016021; GO:0046872; GO:0010638; GO:0015031; GO:0030017,ER to Golgi transport vesicle; ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi membrane; Golgi organization; endoplasmic reticulum membrane; endoplasmic reticulum organization; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; metal ion binding; positive regulation of organelle organization; protein transport; sarcomere,PF03388;,4.00E-45,CHOYP_LOC660183.1.1,,,,,,,LMAN1_MOUSE,Mus musculus (Mouse),endoplasmic reticulum organization [GO:0007029]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; positive regulation of organelle organization [GO:0010638]; protein transport [GO:0015031] comp118540_c1_seq2,995,41.5075,0.58574512,36,20,,4.00E-48,P70207,Plexin-A2 (Plex 2) (Plexin-2),Plexin-A2 (Plex 2) (Plexin-2),GO:0051642; GO:0021935; GO:0005887; GO:0005622; GO:0060174; GO:0021915; GO:0060037; GO:0030334; GO:0017154; GO:0001756,centrosome localization; cerebellar granule cell precursor tangential migration; integral to plasma membrane; intracellular; limb bud formation; neural tube development; pharyngeal system development; regulation of cell migration; semaphorin receptor activity; somitogenesis,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA2_MOUSE,Mus musculus (Mouse),branchiomotor neuron axon guidance [GO:0021785]; cell surface receptor signaling pathway [GO:0007166]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] comp118546_c1_seq2,524,41.2214,0.8102576,3,0,,6.00E-14,P30795,Uncharacterized protein ZMO1242,Uncharacterized protein ZMO1242,GO:0004181; GO:0006508; GO:0008270,metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,,,,,,,,,Y1242_ZYMMO,Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4), comp118546_c1_seq3,886,40.1806,0.58908993,8,14,,2.00E-85,B0JZV4,Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5),Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5),GO:0005829; GO:0004181; GO:0005634; GO:0035611; GO:0006508; GO:0015631; GO:0008270,cytosol; metallocarboxypeptidase activity; nucleus; protein branching point deglutamylation; proteolysis; tubulin binding; zinc ion binding,PF00246;,1.00E-78,CHOYP_LOC100893981.1.1,,,,,,,CBPC5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608] comp118546_c3_seq1,216,45.3704,0.55713646,0,6,,4.00E-30,D2GXM8,Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5),Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5),GO:0005829; GO:0004181; GO:0005634; GO:0035611; GO:0006508; GO:0015631; GO:0008270,cytosol; metallocarboxypeptidase activity; nucleus; protein branching point deglutamylation; proteolysis; tubulin binding; zinc ion binding,PF00246;,,,,,,,,,CBPC5_AILME,Ailuropoda melanoleuca (Giant panda),defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608] comp118550_c0_seq1,444,45.9459,1.09294198,3,122,,1.00E-23,A9CB25,Solute carrier family 22 member 4 (Organic cation/carnitine transporter 1),Solute carrier family 22 member 4 (Organic cation/carnitine transporter 1),GO:0005524; GO:0016021; GO:0015075; GO:0006814; GO:0015293,ATP binding; integral to membrane; ion transmembrane transporter activity; sodium ion transport; symporter activity,PF00083;,,,,,,,,,S22A4_PAPAN,Papio anubis (Olive baboon),carnitine metabolic process [GO:0009437]; sodium ion transport [GO:0006814]; triglyceride metabolic process [GO:0006641] comp118556_c0_seq1,311,37.9421,0.26958804,15,13,,3.00E-23,C9JN71,Zinc finger protein 878,Zinc finger protein 878,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN878_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp118560_c1_seq1,1176,48.2143,0.35280919,43,5,,1.00E-47,O94901,SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1),SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1),GO:0034993; GO:0002080; GO:0090286; GO:0005639; GO:0006998; GO:0090292; GO:0031965,SUN-KASH complex; acrosomal membrane; cytoskeletal anchoring at nuclear membrane; integral to nuclear inner membrane; nuclear envelope organization; nuclear matrix anchoring at nuclear membrane; nuclear membrane,PF09387;PF07738;,,,,,,,,,SUN1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; nuclear envelope organization [GO:0006998]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; ossification [GO:0001503]; response to mechanical stimulus [GO:0009612]; synapsis [GO:0007129] comp118567_c0_seq1,267,44.5693,0.37982392,6,24,,,,,,,,,8.00E-17,CHOYP_CRBN.1.1,,,,,,,,, comp118567_c1_seq1,208,39.4231,0.51701875,1,15,,2.00E-08,Q29B72,Protein cereblon homolog,Protein cereblon homolog,,,PF03226;,,,,,,,,,CRBN_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp118567_c2_seq1,807,44.6097,0.56772467,12,113,,2.00E-29,Q5R6Y2,Protein cereblon,Protein cereblon,GO:0004176; GO:0031464; GO:0005737; GO:0016020; GO:0005634; GO:0043161; GO:0016567,ATP-dependent peptidase activity; Cul4A-RING ubiquitin ligase complex; cytoplasm; membrane; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination,PF02190;PF03226;,,,,,,,,,CRBN_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] comp118580_c0_seq1,638,41.3793,1.3702149,17,68,,1.00E-21,Q8WY41,Nanos homolog 1 (NOS-1) (EC_Rep1a),Nanos homolog 1 (NOS-1) (EC_Rep1a),GO:0003723; GO:0010631; GO:0048471; GO:0030371; GO:0008270,RNA binding; epithelial cell migration; perinuclear region of cytoplasm; translation repressor activity; zinc ion binding,PF05741;,2.00E-16,CHOYP_LOC100313663.1.1,,,,,,,NANO1_HUMAN,Homo sapiens (Human),"cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; negative regulation of translation [GO:0017148]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; posttranscriptional regulation of gene expression [GO:0010608]" comp118581_c0_seq1,769,45.3836,0.68437801,5,0,,5.00E-56,O42469,Transducin-like enhancer protein 1 (Enhancer of split groucho-like protein 1) (ESG1),Transducin-like enhancer protein 1 (Enhancer of split groucho-like protein 1) (ESG1),GO:0005634; GO:0006355,"nucleus; regulation of transcription, DNA-dependent",PF03920;PF00400;,1.00E-89,CHOYP_TLE4.1.1,,,,,,,TLE1_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]" comp118581_c0_seq2,964,47.0954,0.6754951,12,14,,2.00E-75,Q04727,Transducin-like enhancer protein 4,Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4),GO:0007219; GO:0003705; GO:0016055; GO:0003682; GO:0000122; GO:0005654; GO:0003714,Notch signaling pathway; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; Wnt receptor signaling pathway; chromatin binding; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; transcription corepressor activity,PF03920;PF00400;,,,,,,,,,TLE4_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp118581_c0_seq3,515,40.3883,0.97175508,0,0,,,,,,,,,2.00E-66,CHOYP_TLE4.1.1,,,,,,,,, comp118582_c1_seq1,275,40.7273,0.61627609,0,53,,7.00E-06,P00996,Pancreatic secretory trypsin inhibitor (Serine protease inhibitor Kazal-type 1),Serine protease inhibitor Kazal-type 1 (Pancreatic secretory trypsin inhibitor),GO:0005576; GO:0090281; GO:0010751; GO:0050732; GO:1900004; GO:0060046; GO:2001256; GO:0004867,extracellular region; negative regulation of calcium ion import; negative regulation of nitric oxide mediated signal transduction; negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of serine-type endopeptidase activity; regulation of acrosome reaction; regulation of store-operated calcium entry; serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,ISK1_BOVIN,Bos taurus (Bovine),negative regulation of calcium ion import [GO:0090281]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of serine-type endopeptidase activity [GO:1900004]; regulation of acrosome reaction [GO:0060046]; regulation of store-operated calcium entry [GO:2001256] comp118583_c1_seq2,1146,44.5026,0.26462737,2,0,,2.00E-27,Q86TJ5,Zinc finger protein 554,Zinc finger protein 554,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN554_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp118583_c1_seq3,1343,46.761,0.32763192,5,14,,1.00E-63,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp118583_c2_seq1,1117,45.658,0.32728363,37,102,,2.00E-18,P47043,Zinc-responsive transcriptional regulator ZAP1,Zinc-responsive transcriptional regulator ZAP1,GO:0000977; GO:0005634; GO:0045944; GO:0034225; GO:0000981; GO:0008270,RNA polymerase II regulatory region sequence-specific DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; sequence-specific DNA binding RNA polymerase II transcription factor activity; zinc ion binding,PF00096;PF13912;,,,,,,,,,ZAP1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0034225]; transcription, DNA-templated [GO:0006351]" comp118583_c3_seq1,469,42.2175,0.38398867,10,26,,2.00E-28,Q8TF68,Zinc finger protein 384 (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (Trinucleotide repeat-containing gene 1 protein),Zinc finger protein 384 (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (Trinucleotide repeat-containing gene 1 protein),GO:0005925; GO:0046872; GO:0006913; GO:0005634; GO:0050714; GO:0045944; GO:0043565; GO:0006351,"focal adhesion; metal ion binding; nucleocytoplasmic transport; nucleus; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription, DNA-dependent",PF00096;PF13912;,2.00E-41,CHOYP_BRAFLDRAFT_98113.1.1,,,,,,,ZN384_HUMAN,Homo sapiens (Human),"nucleocytoplasmic transport [GO:0006913]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp118583_c3_seq2,228,42.9825,0.47709251,0,0,,6.00E-11,Q92618,Zinc finger protein 516,Zinc finger protein 516,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,3.00E-14,CHOYP_LOC100642338.1.1,,,,,,,ZN516_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cold [GO:0009409]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]" comp118594_c0_seq1,403,39.4541,0.57916891,20,14,,3.00E-52,Q8BH60,Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST),Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST),GO:0000139; GO:0006914; GO:0030054; GO:0030425; GO:0044325; GO:0005886; GO:0014069; GO:0045211; GO:0043234; GO:0051260; GO:0015031; GO:0005083; GO:0007289; GO:0045202; GO:0019905; GO:0030140,Golgi membrane; autophagy; cell junction; dendrite; ion channel binding; plasma membrane; postsynaptic density; postsynaptic membrane; protein complex; protein homooligomerization; protein transport; small GTPase regulator activity; spermatid nucleus differentiation; synapse; syntaxin binding; trans-Golgi network transport vesicle,PF00595;,3.00E-44,CHOYP_GOPC.1.1,,,,,,,GOPC_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; spermatid nucleus differentiation [GO:0007289] comp118594_c1_seq1,244,45.4918,0.43134527,8,0,,1.00E-23,Q9HD26,Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST),Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST),GO:0006888; GO:0000139; GO:0006893; GO:0045176; GO:0030054; GO:0043004; GO:0030425; GO:0005886; GO:0014069; GO:0045211; GO:0043234; GO:0051260; GO:0015031; GO:0005083; GO:0007289; GO:0030140,ER to Golgi vesicle-mediated transport; Golgi membrane; Golgi to plasma membrane transport; apical protein localization; cell junction; cytoplasmic sequestering of CFTR protein; dendrite; plasma membrane; postsynaptic density; postsynaptic membrane; protein complex; protein homooligomerization; protein transport; small GTPase regulator activity; spermatid nucleus differentiation; trans-Golgi network transport vesicle,PF00595;,,,,,,,,,GOPC_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031] comp118595_c1_seq1,276,40.2174,0.81471658,8,14,,6.00E-15,Q3U133,Zinc finger protein 746,Zinc finger protein 746,GO:0005737; GO:0046872; GO:0045892; GO:0070997; GO:0005634; GO:0010941; GO:0044212; GO:0006351,"cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; neuron death; nucleus; regulation of cell death; transcription regulatory region DNA binding; transcription, DNA-dependent",PF12417;PF01352;PF00096;PF13912;,,,,,,,,,ZN746_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp118595_c1_seq2,306,45.4248,0.3823204,10,15,,4.00E-33,Q13360,Zinc finger protein 177,Zinc finger protein 177,GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN177_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp118596_c1_seq1,451,47.8936,0.33235458,11,19,,,,,,,,,4.00E-42,CHOYP_LOC100726123.1.1,,,,,,,,, comp118596_c2_seq1,1011,47.6756,0.52565108,38,28,,1.00E-104,Q9P2N6,KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) (Serum inhibited-related protein) (Testis development protein PRTD),KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) (Serum inhibited-related protein) (Testis development protein PRTD),GO:0043984; GO:0043981; GO:0043982; GO:0000123,histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex,,,,,,,,,,KANL3_HUMAN,Homo sapiens (Human),histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982] comp118601_c4_seq1,508,43.8976,0.49755814,10,30,,3.00E-30,Q13813,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)",GO:0030018; GO:0003779; GO:0051693; GO:0007411; GO:0005509; GO:0006921; GO:0032437; GO:0005829; GO:0005916; GO:0043231; GO:0016328; GO:0016020; GO:0015630; GO:0008091; GO:0005200,Z disc; actin binding; actin filament capping; axon guidance; calcium ion binding; cellular component disassembly involved in execution phase of apoptosis; cuticular plate; cytosol; fascia adherens; intracellular membrane-bounded organelle; lateral plasma membrane; membrane; microtubule cytoskeleton; spectrin; structural constituent of cytoskeleton,PF13499;PF08726;PF00018;PF00435;,7.00E-78,CHOYP_LOC100377364.2.2,,,,,,,SPTN1_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; ER to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165] comp118611_c1_seq1,922,43.2755,0.54793065,10,18,,7.00E-12,Q99550,M-phase phosphoprotein 9,M-phase phosphoprotein 9,GO:0005794; GO:0000139; GO:0005814; GO:0000087; GO:0005634; GO:0005886,Golgi apparatus; Golgi membrane; centriole; mitotic M phase; nucleus; plasma membrane,,,,,,,,,,MPP9_HUMAN,Homo sapiens (Human), comp118611_c1_seq3,789,44.1065,0.58426154,4,0,,4.00E-12,Q99550,M-phase phosphoprotein 9,M-phase phosphoprotein 9,GO:0005794; GO:0000139; GO:0005814; GO:0000087; GO:0005634; GO:0005886,Golgi apparatus; Golgi membrane; centriole; mitotic M phase; nucleus; plasma membrane,,,,,,,,,,MPP9_HUMAN,Homo sapiens (Human), comp118617_c0_seq1,569,37.0826,0.87502528,6,244,,,,,,,,,1.00E-18,CHOYP_SMP_168560.1.1,,,,,,,,, comp118639_c0_seq1,285,33.3333,0.5167182,9,12,,1.00E-10,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,1.00E-13,ruditapes_c9179,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp118651_c0_seq1,270,44.8148,0.07465667,1,25,,9.00E-12,P48441,Alpha-L-iduronidase (EC 3.2.1.76),Alpha-L-iduronidase (EC 3.2.1.76),GO:0003940; GO:0005975; GO:0000902; GO:0048878; GO:0030209; GO:0035108; GO:0005764; GO:0007040; GO:0048705,L-iduronidase activity; carbohydrate metabolic process; cell morphogenesis; chemical homeostasis; dermatan sulfate catabolic process; limb morphogenesis; lysosome; lysosome organization; skeletal system morphogenesis,PF01229;,,,,,,,,,IDUA_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; limb morphogenesis [GO:0035108]; lysosome organization [GO:0007040]; skeletal system morphogenesis [GO:0048705] comp118675_c0_seq4,224,40.625,0.22727726,0,0,,2.00E-06,O61309,Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS),Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS),GO:0010181; GO:0050661; GO:0050660; GO:0020037; GO:0005506; GO:0006809; GO:0004517,FMN binding; NADP binding; flavin adenine dinucleotide binding; heme binding; iron ion binding; nitric oxide biosynthetic process; nitric-oxide synthase activity,PF00667;PF00258;PF00175;PF02898;,,,,,,,,,NOS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),nitric oxide biosynthetic process [GO:0006809] comp118677_c0_seq1,284,42.9577,1.16012293,4,43,,1.00E-19,Q5DU25,IQ motif and SEC7 domain-containing protein 2,IQ motif and SEC7 domain-containing protein 2,GO:0005086; GO:0030036; GO:0030054; GO:0005737; GO:0005634; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cell junction; cytoplasm; nucleus; phospholipid binding; regulation of ARF protein signal transduction,PF01369;,3.00E-23,CHOYP_SIZ.1.1,,,,,,,IQEC2_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] comp118679_c0_seq2,1042,44.1459,0.56840396,14,13,,1.00E-36,Q8HZY8,Coiled-coil domain-containing protein 148,Coiled-coil domain-containing protein 148,,,,,,,,,,,,CC148_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp118692_c0_seq1,538,36.0595,0.66113074,37,33,,2.00E-10,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,4.00E-12,CHOYP_LOC100892567.3.8,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp118722_c2_seq1,519,44.7013,0.69689783,14,43,,6.00E-40,O88368,Microphthalmia-associated transcription factor (Fragment),Microphthalmia-associated transcription factor (Fragment),GO:0003677; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00010;,7.00E-34,CHOYP_LOC100313655.1.1,,,,,,,MITF_RAT,Rattus norvegicus (Rat),"mast cell migration [GO:0097531]; melanocyte differentiation [GO:0030318]; multicellular organism development [GO:0007275]; regulation of apoptotic process [GO:0042981]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp118722_c4_seq1,510,49.2157,0.55901116,8,36,,,,,,,,,3.00E-13,CHOYP_MITF.3.3,,,,,,,,, comp118727_c0_seq1,601,47.7537,0.43877672,0,0,,,,,,,,,8.00E-15,CHOYP_LOC584392.1.1,,,,,,,,, comp118727_c0_seq3,905,45.9669,0.39796604,0,0,,1.00E-84,P50430,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0007417; GO:0005764; GO:0046872; GO:0005739; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; central nervous system development; lysosome; metal ion binding; mitochondrion; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,,,,,,,,,ARSB_RAT,Rattus norvegicus (Rat),autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] comp118727_c0_seq4,813,45.2645,0.36065628,0,0,,3.00E-30,P20713,Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase),Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase),GO:0004065; GO:0046872; GO:0042597,arylsulfatase activity; metal ion binding; periplasmic space,PF00884;,5.00E-57,CHOYP_LOC584392.1.1,,,,,,,ATSA_ENTAE,Enterobacter aerogenes (Aerobacter aerogenes),metabolic process [GO:0008152] comp118739_c0_seq1,402,46.7662,1.36889434,16,16,,,,,,,,,,,4.00E-78,ruditapes_c12661,,,,,,, comp118739_c0_seq2,202,53.9604,1.38098623,0,0,,,,,,,,,,,5.00E-22,ruditapes_c21670,,,,,,, comp118749_c1_seq1,363,44.3526,1.01111878,0,0,,4.00E-10,O24243,(R)-mandelonitrile lyase 1 (EC 4.1.2.10) (Hydroxynitrile lyase 1) ((R)-oxynitrilase 1),(R)-mandelonitrile lyase 1 (EC 4.1.2.10) (Hydroxynitrile lyase 1) ((R)-oxynitrilase 1),GO:0006066; GO:0008812; GO:0050660; GO:0046593,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding; mandelonitrile lyase activity,PF05199;PF00732;,,,,,,,,,MDL1_PRUDU,Prunus dulcis (Almond) (Amygdalus dulcis), comp118749_c1_seq2,455,43.5165,1.02524767,2,15,,2.00E-30,Q47944,L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32),L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32),GO:0006066; GO:0008812; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding,PF05199;PF00732;,,,,,,,,,SDH_GLUOY,Gluconobacter oxydans (Gluconobacter suboxydans), comp118749_c2_seq1,365,47.9452,0.95988132,0,45,,1.00E-13,Q9VGP2,Neither inactivation nor afterpotential protein G (EC 1.-.-.-),Neither inactivation nor afterpotential protein G (EC 1.-.-.-),GO:0006066; GO:0008812; GO:0005576; GO:0050660; GO:0016491; GO:0050896; GO:0001523; GO:0046154; GO:0006810; GO:0007601,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding; oxidoreductase activity; response to stimulus; retinoid metabolic process; rhodopsin metabolic process; transport; visual perception,PF05199;PF00732;,,,,,,,,,NINAG_DROME,Drosophila melanogaster (Fruit fly),response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; rhodopsin metabolic process [GO:0046154]; transport [GO:0006810]; visual perception [GO:0007601] comp118757_c0_seq1,738,40.6504,0.60084125,6,21,,3.00E-08,O35409,Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase),Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase),GO:0004180; GO:0005737; GO:0016805; GO:0006760; GO:0005887; GO:0046872; GO:0008237; GO:0005634; GO:0006508,carboxypeptidase activity; cytoplasm; dipeptidase activity; folic acid-containing compound metabolic process; integral to plasma membrane; metal ion binding; metallopeptidase activity; nucleus; proteolysis,PF02225;PF04389;PF04253;,,,,,,,,,FOLH1_MOUSE,Mus musculus (Mouse),C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; proteolysis [GO:0006508] comp118757_c1_seq1,1603,36.8684,0.27620261,0,0,,4.00E-18,O54697,N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase),N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase),GO:0016324; GO:0004180; GO:0016805; GO:0016021; GO:0046872; GO:0008237; GO:0006508,apical plasma membrane; carboxypeptidase activity; dipeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; proteolysis,PF02225;PF04389;PF04253;,,,,,,,,,NALDL_RAT,Rattus norvegicus (Rat), comp118757_c1_seq2,1921,37.5846,0.22190414,4,31,,8.00E-20,O54697,N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase),N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase),GO:0016324; GO:0004180; GO:0016805; GO:0016021; GO:0046872; GO:0008237; GO:0006508,apical plasma membrane; carboxypeptidase activity; dipeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; proteolysis,PF02225;PF04389;PF04253;,,,,,,,,,NALDL_RAT,Rattus norvegicus (Rat), comp118759_c1_seq1,213,36.1502,0.58551222,4,12,,,,,,,,,,,3.00E-12,ruditapes_c24074,,,,,,, comp118759_c1_seq2,249,36.1446,0.37956078,69,37,,,,,,,,,,,4.00E-11,ruditapes2_c1783,,,,,,, comp118772_c0_seq1,1074,44.1341,0.58351025,16,9,,8.00E-08,Q8C1B1,Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1),Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1),GO:0005737; GO:0005874,cytoplasm; microtubule,PF17095;PF11971;PF08683;,,,,,,,,,CAMP2_MOUSE,Mus musculus (Mouse),microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; regulation of organelle organization [GO:0033043] comp118772_c0_seq2,878,45.4442,0.60543446,0,0,,5.00E-08,Q8C1B1,Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1),Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1),GO:0005737; GO:0005874,cytoplasm; microtubule,PF17095;PF11971;PF08683;,7.00E-18,CHOYP_LOC100932567.1.1,,,,,,,CAMP2_MOUSE,Mus musculus (Mouse),microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; regulation of organelle organization [GO:0033043] comp118777_c0_seq1,841,40.1902,0.88454795,26,13,,3.00E-08,Q8TB03,Uncharacterized protein CXorf38,Uncharacterized protein CXorf38,,,PF15112;,,,,,,,,,CX038_HUMAN,Homo sapiens (Human), comp118779_c1_seq1,414,40.3382,0.54430513,7,11,,1.00E-54,Q91W86,Vacuolar protein sorting-associated protein 11 homolog,Vacuolar protein sorting-associated protein 11 homolog,GO:0005884; GO:0005769; GO:0030139; GO:0006886; GO:0031902; GO:0005765; GO:0000166; GO:0016192; GO:0008270,actin filament; early endosome; endocytic vesicle; intracellular protein transport; late endosome membrane; lysosomal membrane; nucleotide binding; vesicle-mediated transport; zinc ion binding,PF00637;PF12451;,5.00E-66,CHOYP_VPS11.3.3,2.00E-75,ruditapes_c16567,,,,,VPS11_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of organelle assembly [GO:1902115]; regulation of protein stability [GO:0031647]; regulation of SNARE complex assembly [GO:0035542]; toxin transport [GO:1901998]; vesicle docking involved in exocytosis [GO:0006904] comp118787_c0_seq1,768,46.0938,0.71185642,20,22,,4.00E-61,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp118787_c1_seq2,744,49.8656,0.65008843,17,18,,6.00E-22,Q9NYQ6,Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007417; GO:0048105; GO:0001736; GO:0042249; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity; establishment of planar polarity of embryonic epithelium; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp118787_c2_seq1,366,45.3552,0.75282613,8,15,,1.00E-09,P97291,Cadherin-8,Cadherin-8,GO:0043679; GO:0005509; GO:0007156; GO:0016021; GO:0005886; GO:0009409; GO:0043083; GO:0035249,"axon terminus; calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane; response to cold; synaptic cleft; synaptic transmission, glutamatergic",PF00028;PF01049;,,,,,,,,,CADH8_MOUSE,Mus musculus (Mouse),"chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to cold [GO:0009409]; synaptic transmission, glutamatergic [GO:0035249]" comp11878_c0_seq1,287,41.4634,0.49231367,3,1,,,,,,,,,5.00E-20,CHOYP_DTNA.1.1,,,,,,,,, comp118793_c0_seq2,1074,47.1136,0.33947577,3,18,,4.00E-137,Q9R1S8,Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH),Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH),GO:0004198; GO:0005634; GO:0097264,calcium-dependent cysteine-type endopeptidase activity; nucleus; self proteolysis,PF01067;PF04212;PF00648;,1.00E-123,CHOYP_CAPN7.2.2,,,,,,,CAN7_MOUSE,Mus musculus (Mouse),positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264] comp118793_c0_seq3,878,47.4943,0.36750954,0,3,,2.00E-91,Q9R1S8,Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH),Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH),GO:0004198; GO:0005634; GO:0097264,calcium-dependent cysteine-type endopeptidase activity; nucleus; self proteolysis,PF01067;PF04212;PF00648;,,,,,,,,,CAN7_MOUSE,Mus musculus (Mouse),positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264] comp118801_c0_seq2,1023,41.9355,0.78925422,51,23,,5.00E-52,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,2.00E-13,CHOYP_NEMVEDRAFT_V1G199550.1.1,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp118819_c0_seq1,491,48.2688,1.17143343,0,87,,1.00E-24,Q8IYQ7,Threonine synthase-like 1 (TSH1),Threonine synthase-like 1 (TSH1),,,PF00291;PF01202;PF14821;,,,,,,,,,THNS1_HUMAN,Homo sapiens (Human), comp118821_c0_seq1,1321,34.8978,0.48118802,46,442,,,,,,,,,,,1.00E-21,ruditapes_c16928,,,,,,, comp118827_c0_seq1,318,43.0818,0.41772565,8,13,,9.00E-08,Q6CBI8,Probable cytosolic iron-sulfur protein assembly protein 1,Probable cytosolic iron-sulfur protein assembly protein 1,GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,,,,,,,,,CIAO1_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),iron-sulfur cluster assembly [GO:0016226] comp118827_c1_seq1,602,45.6811,0.39424757,20,6,,3.00E-82,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,8.00E-104,CHOYP_EMAL6.1.1,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp118828_c0_seq1,689,44.4122,0.32429036,10,66,,5.00E-101,Q62073,Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1),Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1),GO:0005524; GO:0007252; GO:0004708; GO:0004709; GO:0001525; GO:0006915; GO:0005737; GO:0000287; GO:2001234; GO:0060546; GO:2000378; GO:1902443; GO:0001841; GO:0005886; GO:0043123; GO:0046330; GO:0043507; GO:0006355; GO:0006950; GO:0006351; GO:0007179,"ATP binding; I-kappaB phosphorylation; MAP kinase kinase activity; MAP kinase kinase kinase activity; angiogenesis; apoptotic process; cytoplasm; magnesium ion binding; negative regulation of apoptotic signaling pathway; negative regulation of necroptosis; negative regulation of reactive oxygen species metabolic process; negative regulation of ripoptosome assembly involved in necroptosis; neural tube formation; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of JUN kinase activity; regulation of transcription, DNA-dependent; response to stress; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway",PF07714;,5.00E-107,CHOYP_M3K7.1.4,,,,,,,M3K7_MOUSE,Mus musculus (Mouse),"activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; I-kappaB phosphorylation [GO:0007252]; MAPK cascade [GO:0000165]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of necroptotic process [GO:0060546]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; neural tube formation [GO:0001841]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp118828_c1_seq1,227,47.1366,0.48753619,2,11,,4.00E-08,Q62406,Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK),Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK),GO:0005524; GO:0045087; GO:0070498; GO:0005811; GO:0031663; GO:0016020; GO:0090370; GO:0045892; GO:0005634; GO:0043507; GO:0051092; GO:0046777; GO:0004672; GO:0004674; GO:0032494; GO:0034134; GO:0034142,"ATP binding; innate immune response; interleukin-1-mediated signaling pathway; lipid particle; lipopolysaccharide-mediated signaling pathway; membrane; negative regulation of cholesterol efflux; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; protein autophosphorylation; protein kinase activity; protein serine/threonine kinase activity; response to peptidoglycan; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway",PF00531;PF00069;,,,,,,,,,IRAK1_MOUSE,Mus musculus (Mouse),"activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine-mediated signaling pathway [GO:0019221]; innate immune response [GO:0045087]; interleukin-1-mediated signaling pathway [GO:0070498]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; regulation of cytokine-mediated signaling pathway [GO:0001959]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to peptidoglycan [GO:0032494]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]" comp118833_c0_seq1,771,45.655,0.22436825,20,22,,3.00E-102,P10253,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase],Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase],GO:0004558; GO:0030246; GO:0060048; GO:0002086; GO:0006006; GO:0005980; GO:0007626; GO:0005765; GO:0007040; GO:0032450; GO:0000023; GO:0046716; GO:0050885; GO:0050884; GO:0002026; GO:0005985; GO:0043587; GO:0043181; GO:0055010,alpha-glucosidase activity; carbohydrate binding; cardiac muscle contraction; diaphragm contraction; glucose metabolic process; glycogen catabolic process; locomotory behavior; lysosomal membrane; lysosome organization; maltose alpha-glucosidase activity; maltose metabolic process; muscle cell cellular homeostasis; neuromuscular process controlling balance; neuromuscular process controlling posture; regulation of the force of heart contraction; sucrose metabolic process; tongue morphogenesis; vacuolar sequestering; ventricular cardiac muscle tissue morphogenesis,PF13802;PF01055;PF16863;PF00088;,,,,,,,,,LYAG_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] comp118843_c0_seq1,866,43.418,0.67846365,38,21,,2.00E-19,Q6PGL7,WASH complex subunit FAM21,WASH complex subunit FAM21,GO:0071203; GO:0005769; GO:0031901; GO:0042147,"WASH complex; early endosome; early endosome membrane; retrograde transport, endosome to Golgi",PF15255;,,,8.00E-34,ruditapes_c10674,,,,,FAM21_MOUSE,Mus musculus (Mouse),"protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp118844_c0_seq1,721,36.1997,0.38358988,11,59,,,,,,,,,1.00E-13,CHOYP_contig_020781,,,,,,,,, comp118850_c0_seq1,745,43.0872,0.32117475,9,4,,4.00E-40,P54098,DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha),DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha),GO:0003677; GO:0006261; GO:0003887; GO:0007568; GO:0006287; GO:0008219; GO:0003682; GO:0004527; GO:0005760; GO:0006264; GO:0005743; GO:0042645,"DNA binding; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; aging; base-excision repair, gap-filling; cell death; chromatin binding; exonuclease activity; gamma DNA polymerase complex; mitochondrial DNA replication; mitochondrial inner membrane; mitochondrial nucleoid",PF00476;,,,,,,,,,DPOG1_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-dependent DNA replication [GO:0006261]; DNA metabolic process [GO:0006259]; mitochondrial DNA replication [GO:0006264]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416]" comp118850_c0_seq2,686,42.4198,0.32823768,0,11,,5.00E-26,Q91684,DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit),DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit),GO:0003677; GO:0006261; GO:0003887; GO:0003682; GO:0005760; GO:0042645,DNA binding; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; chromatin binding; gamma DNA polymerase complex; mitochondrial nucleoid,PF00476;,,,,,,,,,DPOG1_XENLA,Xenopus laevis (African clawed frog),DNA replication [GO:0006260] comp118854_c0_seq1,777,46.4607,0.23888519,18,31,,4.00E-21,A6H8Y1,Transcription factor TFIIIB component B'' homolog (Transcription factor IIIB 150) (TFIIIB150) (Transcription factor-like nuclear regulator),Transcription factor TFIIIB component B'' homolog (Transcription factor IIIB 150) (TFIIIB150) (Transcription factor-like nuclear regulator),GO:0003677; GO:0003682; GO:0005654; GO:0006355; GO:0006383,"DNA binding; chromatin binding; nucleoplasm; regulation of transcription, DNA-dependent; transcription from RNA polymerase III promoter",,1.00E-13,CHOYP_BDP1.1.2,,,,,,,BDP1_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp118856_c0_seq1,528,47.1591,0.34129155,30,7,,4.00E-10,Q5R3Z8,F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2),F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2),GO:0016020,membrane,PF12937;PF13516;,4.00E-24,CHOYP_NEMVEDRAFT_V1G214518.1.1,,,,,,,FBXL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp118857_c0_seq2,570,38.0702,0.40239729,13,21,,2.00E-37,Q6Y685,Transforming acidic coiled-coil-containing protein 1,Transforming acidic coiled-coil-containing protein 1,GO:0007049; GO:0051301; GO:0021987; GO:0005737; GO:0022027; GO:0000226; GO:0005815; GO:0022008; GO:0005634; GO:0032886,cell cycle; cell division; cerebral cortex development; cytoplasm; interkinetic nuclear migration; microtubule cytoskeleton organization; microtubule organizing center; neurogenesis; nucleus; regulation of microtubule-based process,PF05010;,2.00E-35,CHOYP_TACC1.1.2,,,,,,,TACC1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neurogenesis [GO:0022008]; regulation of microtubule-based process [GO:0032886] comp118871_c0_seq1,704,40.9091,0.63784999,5,120,,,,,,,,,4.00E-51,CHOYP_ZGC_113208.1.1,,,,,,,,, comp118876_c0_seq1,1375,39.2727,0.3631113,58,278,,4.00E-95,Q8QZS3,Folliculin,Folliculin,GO:0031929; GO:0007043; GO:0005737; GO:0030097; GO:0001701; GO:2001170; GO:0070373; GO:0035024; GO:0032007; GO:0016525; GO:0030308; GO:0030336; GO:1901723; GO:1901856; GO:2000506; GO:1901859; GO:0010823; GO:1901862; GO:1901874; GO:0051898; GO:1900181; GO:0000122; GO:0005634; GO:0005886; GO:0032008; GO:0045785; GO:2001244; GO:0001934; GO:0045944; GO:0030511; GO:0032403; GO:0032465; GO:0035065; GO:2000973,TOR signaling cascade; cell-cell junction assembly; cytoplasm; hemopoiesis; in utero embryonic development; negative regulation of ATP biosynthetic process; negative regulation of ERK1 and ERK2 cascade; negative regulation of Rho protein signal transduction; negative regulation of TOR signaling cascade; negative regulation of angiogenesis; negative regulation of cell growth; negative regulation of cell migration; negative regulation of cell proliferation involved in kidney development; negative regulation of cellular respiration; negative regulation of energy homeostasis; negative regulation of mitochondrial DNA metabolic process; negative regulation of mitochondrion organization; negative regulation of muscle tissue development; negative regulation of post-translational protein modification; negative regulation of protein kinase B signaling cascade; negative regulation of protein localization to nucleus; negative regulation of transcription from RNA polymerase II promoter; nucleus; plasma membrane; positive regulation of TOR signaling cascade; positive regulation of cell adhesion; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; protein complex binding; regulation of cytokinesis; regulation of histone acetylation; regulation of pro-B cell differentiation,PF16692;,2.00E-27,CHOYP_FLCN.1.1,,,,,,,FLCN_MOUSE,Mus musculus (Mouse),"cell-cell junction assembly [GO:0007043]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; negative regulation of angiogenesis [GO:0016525]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in kidney development [GO:1901723]; negative regulation of cellular respiration [GO:1901856]; negative regulation of energy homeostasis [GO:2000506]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of gene expression [GO:0010629]; negative regulation of mitochondrial DNA metabolic process [GO:1901859]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of post-translational protein modification [GO:1901874]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of autophagy [GO:0010508]; positive regulation of cell adhesion [GO:0045785]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cytokinesis [GO:0032465]; regulation of histone acetylation [GO:0035065]; regulation of pro-B cell differentiation [GO:2000973]; regulation of protein phosphorylation [GO:0001932]; regulation of TOR signaling [GO:0032006]; TOR signaling [GO:0031929]" comp118877_c1_seq2,967,39.4002,0.34729849,6,0,,9.00E-67,O93327,Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y),Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y),GO:0003677; GO:0016568; GO:0000786; GO:0006334; GO:0005634,DNA binding; chromatin modification; nucleosome; nucleosome assembly; nucleus,PF00125;PF16211;PF01661;,8.00E-81,CHOYP_LOC100369232.1.1,,,,,,,H2AY_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; regulation of histone methylation [GO:0031060]; regulation of lipid metabolic process [GO:0019216]" comp118887_c0_seq1,1101,37.6022,0.33587349,24,117,,1.00E-35,Q0P5H1,Prenylcysteine oxidase-like (EC 1.8.3.-),Prenylcysteine oxidase-like (EC 1.8.3.-),GO:0005576; GO:0030328; GO:0001735,extracellular region; prenylcysteine catabolic process; prenylcysteine oxidase activity,PF07156;,,,,,,,,,PCYXL_BOVIN,Bos taurus (Bovine),prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328] comp118888_c0_seq2,694,43.2277,0.49530191,5,6,,8.00E-66,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp118888_c0_seq3,733,44.3383,0.4198452,2,0,,,,,,,,,2.00E-80,CHOYP_TPPC8.1.1,,,,,,,,, comp118889_c0_seq1,1056,39.1098,0.74398265,38,27,,8.00E-81,Q64343,ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog),ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog),GO:0043531; GO:0005524; GO:0006200; GO:0005794; GO:0042987; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0009897; GO:0034436; GO:0034437; GO:0034375; GO:0016021; GO:0032367; GO:0034374; GO:0005739; GO:0010888; GO:0010745; GO:0033700; GO:0055091; GO:0005548; GO:0045542; GO:0010875; GO:0055037; GO:0010872; GO:0006355; GO:0055099; GO:0033993; GO:0043691; GO:0034041; GO:0019534,"ADP binding; ATP binding; ATP catabolic process; Golgi apparatus; amyloid precursor protein catabolic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; external side of plasma membrane; glycoprotein transport; glycoprotein transporter activity; high-density lipoprotein particle remodeling; integral to membrane; intracellular cholesterol transport; low-density lipoprotein particle remodeling; mitochondrion; negative regulation of lipid storage; negative regulation of macrophage derived foam cell differentiation; phospholipid efflux; phospholipid homeostasis; phospholipid transporter activity; positive regulation of cholesterol biosynthetic process; positive regulation of cholesterol efflux; recycling endosome; regulation of cholesterol esterification; regulation of transcription, DNA-dependent; response to high density lipoprotein particle stimulus; response to lipid; reverse cholesterol transport; sterol-transporting ATPase activity; toxin transporter activity",PF01061;PF00005;,5.00E-71,CHOYP_ABCG1.1.1,,,,,,,ABCG1_MOUSE,Mus musculus (Mouse),"amyloid precursor protein catabolic process [GO:0042987]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; glycoprotein transport [GO:0034436]; high-density lipoprotein particle remodeling [GO:0034375]; intracellular cholesterol transport [GO:0032367]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol efflux [GO:0010875]; regulation of cholesterol esterification [GO:0010872]; regulation of transcription, DNA-templated [GO:0006355]; response to high density lipoprotein particle [GO:0055099]; response to lipid [GO:0033993]; response to organic substance [GO:0010033]; reverse cholesterol transport [GO:0043691]" comp118897_c0_seq1,1438,43.1154,0.41261011,53,106,,2.00E-173,Q5R9T5,Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1),Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1),GO:0035339; GO:0009058; GO:0016021; GO:0030170; GO:0004758; GO:0006665,SPOTS complex; biosynthetic process; integral to membrane; pyridoxal phosphate binding; serine C-palmitoyltransferase activity; sphingolipid metabolic process,PF00155;,3.00E-94,CHOYP_CLCA1.1.1,,,,,,,SPTC1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),biosynthetic process [GO:0009058]; sphingolipid metabolic process [GO:0006665] comp118898_c0_seq1,962,36.9023,0.52143642,30,21,,1.00E-48,A0JNB1,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp118900_c0_seq1,842,41.0926,0.36676759,0,0,,,,,,,,,3.00E-92,CHOYP_KIAA0556.1.1,,,,,,,,, comp118900_c0_seq2,2356,43.4635,0.41916323,114,38,,0,O60303,Uncharacterized protein KIAA0556,Protein KIAA0556,GO:0005634; GO:0005886,nucleus; plasma membrane,PF14652;,,,,,,,,,K0556_HUMAN,Homo sapiens (Human), comp118905_c1_seq1,391,48.0818,0.57837173,4,34,,2.00E-60,B0LPN4,Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor),Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor),GO:0031672; GO:0030018; GO:0005509; GO:0048763; GO:0019722; GO:0071313; GO:0003143; GO:0031234; GO:0016021; GO:0071421; GO:0043005; GO:0005635; GO:0043234; GO:0051481; GO:0051592; GO:0042493; GO:0032026; GO:0007584; GO:0005219; GO:0042383; GO:0070296; GO:0033017,A band; Z disc; calcium ion binding; calcium-induced calcium release activity; calcium-mediated signaling; cellular response to caffeine; embryonic heart tube morphogenesis; extrinsic to internal side of plasma membrane; integral to membrane; manganese ion transmembrane transport; neuron projection; nuclear envelope; protein complex; reduction of cytosolic calcium ion concentration; response to calcium ion; response to drug; response to magnesium ion; response to nutrient; ryanodine-sensitive calcium-release channel activity; sarcolemma; sarcoplasmic reticulum calcium ion transport; sarcoplasmic reticulum membrane,PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,1.00E-86,CHOYP_LOC100643070.1.1,,,,,,,RYR2_RAT,Rattus norvegicus (Rat),calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; embryonic heart tube morphogenesis [GO:0003143]; ion transmembrane transport [GO:0034220]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to magnesium ion [GO:0032026]; response to nutrient [GO:0007584]; sarcoplasmic reticulum calcium ion transport [GO:0070296] comp11890_c0_seq1,246,42.2764,0.4582636,0,1,,9.00E-24,Q7SYC9,Choline transporter-like protein 2 (Solute carrier family 44 member 2),Choline transporter-like protein 2 (Solute carrier family 44 member 2),GO:0016021,integral to membrane,PF04515;,,,,,,,,,CTL2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp118912_c0_seq1,663,43.2881,0.49277769,15,45,,2.00E-63,Q9Z1J2,Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2),Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2),GO:0005524; GO:0051301; GO:0046872; GO:0007067; GO:0005634; GO:0004674,ATP binding; cell division; metal ion binding; mitosis; nucleus; protein serine/threonine kinase activity,PF00069;,1.00E-25,CHOYP_NEK4.2.8,,,,,,,NEK4_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]" comp118913_c0_seq2,782,47.8261,0.3850566,25,14,,4.00E-32,O60494,Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0009235; GO:0015889; GO:0005829; GO:0030139; GO:0005783; GO:0010008; GO:0031232; GO:0042157; GO:0042953; GO:0043202; GO:0005765; GO:0042803; GO:0004872; GO:0006898; GO:0001894; GO:0005215; GO:0042359,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; cobalamin metabolic process; cobalamin transport; cytosol; endocytic vesicle; endoplasmic reticulum; endosome membrane; extrinsic to external side of plasma membrane; lipoprotein metabolic process; lipoprotein transport; lysosomal lumen; lysosomal membrane; protein homodimerization activity; receptor activity; receptor-mediated endocytosis; tissue homeostasis; transporter activity; vitamin D metabolic process,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_HUMAN,Homo sapiens (Human),cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359] comp118917_c0_seq1,975,46.359,0.79657693,0,0,,2.00E-60,P31684,4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1),4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL1_SOLTU,Solanum tuberosum (Potato),phenylpropanoid metabolic process [GO:0009698] comp118917_c0_seq2,550,43.6364,0.78945744,0,0,,3.00E-16,P31686,4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment),4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL1_SOYBN,Glycine max (Soybean) (Glycine hispida),phenylpropanoid metabolic process [GO:0009698] comp118917_c0_seq4,989,44.2872,0.81481565,0,0,,4.00E-56,P31684,4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1),4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL1_SOLTU,Solanum tuberosum (Potato),phenylpropanoid metabolic process [GO:0009698] comp118928_c1_seq1,243,44.856,1.16192444,0,0,,2.00E-08,Q10280,Transcription factor gaf1 (Gaf-1),Transcription factor gaf1 (Gaf-1),GO:0000978; GO:0001077; GO:0032153; GO:0005829; GO:0005634; GO:0008270,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell division site; cytosol; nucleus; zinc ion binding,PF08550;PF00320;,,,,,,,,,GAF1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell differentiation [GO:0030154]; negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter [GO:1902625] comp118928_c1_seq2,298,47.651,1.00914378,0,5,,4.00E-24,P0C6A0,GATA-type zinc finger protein 1 (GATA-like protein 1) (GLP-1),GATA-type zinc finger protein 1 (GATA-like protein 1) (GLP-1),GO:0007275; GO:0043066; GO:0000122; GO:0005634; GO:0048599; GO:0070374; GO:0033138; GO:0032092; GO:0043565; GO:0003700; GO:0007283; GO:0006351; GO:0008270,"multicellular organismal development; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; oocyte development; positive regulation of ERK1 and ERK2 cascade; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; spermatogenesis; transcription, DNA-dependent; zinc ion binding",PF00320;,,,,,,,,,ZGLP1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oocyte development [GO:0048599]; spermatogenesis [GO:0007283] comp118934_c0_seq1,474,41.9831,0.43313263,10,16,,2.00E-23,Q2T9J0,"Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]","Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]",GO:0005777; GO:0051260; GO:0016485; GO:0006508; GO:0031998; GO:0004252,peroxisome; protein homooligomerization; protein processing; proteolysis; regulation of fatty acid beta-oxidation; serine-type endopeptidase activity,,,,,,,,,,TYSD1_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998] comp118936_c0_seq2,1108,49.8195,0.4368037,9,0,,6.00E-77,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,1.00E-41,CHOYP_LOC100166052.1.1,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp118938_c1_seq1,597,36.6834,0.70602323,26,140,,,,,,,,,1.00E-12,CHOYP_contig_048413,,,,,,,,, comp118942_c0_seq1,578,40.3114,0.1708978,6,13,,2.00E-36,Q9JHG1,Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (EC 2.4.1.198) (Down syndrome critical region protein 5 homolog) (Phosphatidylinositol-glycan biosynthesis class P protein) (PIG-P),Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (EC 2.4.1.198) (Down syndrome critical region protein 5 homolog) (Phosphatidylinositol-glycan biosynthesis class P protein) (PIG-P),GO:0006506; GO:0000506; GO:0016021; GO:0017176,GPI anchor biosynthetic process; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to membrane; phosphatidylinositol N-acetylglucosaminyltransferase activity,PF08510;,,,,,,,,,PIGP_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp118950_c0_seq1,230,43.0435,0.66544468,2,9,,1.00E-12,Q62261,"Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)","Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)",GO:0043001; GO:0031430; GO:0007184; GO:0051693; GO:0030673; GO:0007182; GO:0032437; GO:0071709; GO:0000281; GO:0005730; GO:0005634; GO:0005543; GO:0072661; GO:0008091; GO:0005200,Golgi to plasma membrane protein transport; M band; SMAD protein import into nucleus; actin filament capping; axolemma; common-partner SMAD protein phosphorylation; cuticular plate; membrane assembly; mitotic cytokinesis; nucleolus; nucleus; phospholipid binding; protein targeting to plasma membrane; spectrin; structural constituent of cytoskeleton,PF00307;PF00435;,,,,,,,,,SPTB2_MOUSE,Mus musculus (Mouse),actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184] comp118950_c2_seq1,433,41.3395,0.81334767,5,42,,,,,,,,,7.00E-14,CHOYP_LOC100377364.2.2,,,,,,,,, comp118961_c0_seq1,941,44.3146,0.43848674,50,18,,4.00E-28,Q66JZ4,"T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)","T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)",GO:0005739,mitochondrion,PF14687;PF14688;,,,,,,,,,CC023_MOUSE,Mus musculus (Mouse), comp118963_c0_seq2,1258,36.9634,0.68181182,5,67,,1.00E-14,Q9XWB9,BTB and MATH domain-containing protein 36,BTB and MATH domain-containing protein 36,,,PF00651;PF00917;,,,,,,,,,BAT36_CAEEL,Caenorhabditis elegans, comp118965_c1_seq1,497,50.7042,0.83069561,21,15,,5.00E-30,A1XQX0,Neurexin-1a (Neurexin Ia-alpha) (Neurexin-1a-alpha),Neurexin-1a (Neurexin Ia-alpha) (Neurexin-1a-alpha),GO:0007155; GO:0016021; GO:0046872; GO:0007269; GO:0051965; GO:0090129; GO:0007416,cell adhesion; integral to membrane; metal ion binding; neurotransmitter secretion; positive regulation of synapse assembly; positive regulation of synapse maturation; synapse assembly,PF00008;PF02210;PF01034;,,,,,,,,,NR1AA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; sprouting angiogenesis [GO:0002040] comp118980_c0_seq1,485,44.9485,0.79432596,6,71,,5.00E-17,Q24180,Deformed epidermal autoregulatory factor 1 (Protein DEAF-1),Deformed epidermal autoregulatory factor 1 (Protein DEAF-1),GO:0009792; GO:0046872; GO:0005634; GO:0005700; GO:0045893; GO:0050776; GO:0006357; GO:0043565; GO:0003700; GO:0006351,"embryo development ending in birth or egg hatching; metal ion binding; nucleus; polytene chromosome; positive regulation of transcription, DNA-dependent; regulation of immune response; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01342;PF01753;,1.00E-11,CHOYP_TTC3.1.1,,,,,,,DEAF1_DROME,Drosophila melanogaster (Fruit fly),"embryo development ending in birth or egg hatching [GO:0009792]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of immune response [GO:0050776]; regulation of multicellular organismal development [GO:2000026]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp118982_c0_seq1,857,41.3069,0.38342749,38,46,,,,,,,,,2.00E-36,CHOYP_LOC100747478.1.1,,,,,,,,, comp118982_c2_seq1,385,43.6364,0.65795898,0,0,,6.00E-11,Q8BL66,Early endosome antigen 1,Early endosome antigen 1,GO:0005545; GO:0031410; GO:0005829; GO:0005769; GO:0031901; GO:0006897; GO:0019897; GO:0046872; GO:0005969; GO:0006906,1-phosphatidylinositol binding; cytoplasmic vesicle; cytosol; early endosome; early endosome membrane; endocytosis; extrinsic to plasma membrane; metal ion binding; serine-pyruvate aminotransferase complex; vesicle fusion,PF01363;,,,,,,,,,EEA1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; vesicle fusion [GO:0006906] comp118982_c2_seq2,725,41.1034,0.49051938,22,9,,3.00E-20,Q0P4S0,Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28),Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28),GO:0005829; GO:0031901; GO:0046872; GO:0007175; GO:0032266,cytosol; early endosome membrane; metal ion binding; negative regulation of epidermal growth factor-activated receptor activity; phosphatidylinositol-3-phosphate binding,PF01363;,,,,,,,,,LST2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp118984_c0_seq1,824,43.6893,1.19679796,14,37,,1.00E-46,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,7.00E-24,CHOYP_BRAFLDRAFT_91636.1.11,,,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp118990_c2_seq1,409,43.2763,0.94907975,2,31,,,,,,,,,7.00E-33,CHOYP_LOC100371883.1.1,,,,,,,,, comp118993_c0_seq1,873,43.7572,0.55286101,61,44,,8.00E-08,Q5VT06,Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),GO:0005813; GO:0005737; GO:0005634; GO:0005819,centrosome; cytoplasm; nucleus; spindle,PF01302;,7.00E-18,CHOYP_CEP350.1.1,,,,,,,CE350_HUMAN,Homo sapiens (Human),microtubule anchoring [GO:0034453] comp118997_c1_seq1,1342,41.5797,0.57118586,0,0,,1.00E-44,Q9U1H9,Nuclear RNA export factor 1 (Protein small bristles) (DmNXF1) (Protein tip-associating),Nuclear RNA export factor 1 (Protein small bristles) (DmNXF1) (Protein tip-associating),GO:0003723; GO:0005737; GO:0006378; GO:0031965; GO:0005654; GO:0000166; GO:0016973,RNA binding; cytoplasm; mRNA polyadenylation; nuclear membrane; nucleoplasm; nucleotide binding; poly(A)+ mRNA export from nucleus,PF02136;PF09162;PF03943;,,,,,,,,,NXF1_DROME,Drosophila melanogaster (Fruit fly),adult behavior [GO:0030534]; long-term memory [GO:0007616]; mRNA export from nucleus [GO:0006406]; mRNA polyadenylation [GO:0006378]; nuclear export [GO:0051168]; poly(A)+ mRNA export from nucleus [GO:0016973] comp118997_c1_seq3,1404,40.7407,0.56559179,0,0,,1.00E-71,P58797,Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP),Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP),GO:0003723; GO:0005737; GO:0006406; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA export from nucleus; nucleotide binding; nucleus,PF02136;PF09162;PF03943;,,,,,,,,,NXF1_COTJA,Coturnix coturnix japonica (Japanese quail) (Coturnix japonica),mRNA export from nucleus [GO:0006406] comp118997_c1_seq4,996,39.6586,0.54514974,0,0,,6.00E-13,Q9XVS8,Nuclear RNA export factor 2,Nuclear RNA export factor 2,GO:0003723; GO:0051028; GO:0005634,RNA binding; mRNA transport; nucleus,,,,,,,,,,NXF2_CAEEL,Caenorhabditis elegans,poly(A)+ mRNA export from nucleus [GO:0016973] comp118997_c1_seq6,1058,38.6578,0.53771991,0,0,,,,,,,,,7.00E-19,CHOYP_NXF1.1.2,,,,,,,,, comp118998_c0_seq1,786,45.6743,0.41562664,21,141,,1.00E-61,Q3KR82,Zinc transporter ZIP9 (Solute carrier family 39 member 9) (Zrt- and Irt-like protein 9) (ZIP-9),Zinc transporter ZIP9 (Solute carrier family 39 member 9) (Zrt- and Irt-like protein 9) (ZIP-9),GO:0016021; GO:0046873; GO:0006829,integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,3.00E-54,CHOYP_BRAFLDRAFT_210496.1.1,,,,,,,S39A9_RAT,Rattus norvegicus (Rat),zinc II ion transport [GO:0006829] comp119007_c0_seq1,835,39.4012,0.42619669,19,122,,7.00E-09,P14885,Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (Fragment),Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (Fragment),GO:0051693; GO:0060271; GO:0005737; GO:0005856; GO:0046872,actin filament capping; cilium morphogenesis; cytoplasm; cytoskeleton; metal ion binding,PF00626;,,,,,,,,,GELS_XENLA,Xenopus laevis (African clawed frog),actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium morphogenesis [GO:0060271] comp119007_c1_seq1,310,40.9677,0.46510953,1,58,,8.00E-41,Q7JQD3,Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1),Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1),GO:0003779; GO:0051693; GO:0030043; GO:0030041; GO:0051014; GO:0045010; GO:0005509; GO:0005737; GO:0005856; GO:0007275,actin binding; actin filament capping; actin filament fragmentation; actin filament polymerization; actin filament severing; actin nucleation; calcium ion binding; cytoplasm; cytoskeleton; multicellular organismal development,PF00626;,3.00E-42,CHOYP_LOC100371249.1.1,,,,,,,GELS1_LUMTE,Lumbricus terrestris (Common earthworm),actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; multicellular organism development [GO:0007275] comp119018_c0_seq1,512,50.7812,0.51910912,4,8,,6.00E-17,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp119018_c0_seq2,643,46.5008,0.48997612,16,14,,9.00E-09,Q8N328,PiggyBac transposable element-derived protein 3,PiggyBac transposable element-derived protein 3,,,PF13843;,,,,,,,,,PGBD3_HUMAN,Homo sapiens (Human), comp119033_c0_seq1,909,49.835,0.99442028,2,325,female>male,3.00E-42,Q70PU1,Peptidoglycan-recognition protein SC2 (EC 3.5.1.28),Peptidoglycan-recognition protein SC2 (EC 3.5.1.28),GO:0008745; GO:0005576; GO:0045087; GO:0009253; GO:0008270,N-acetylmuramoyl-L-alanine amidase activity; extracellular region; innate immune response; peptidoglycan catabolic process; zinc ion binding,PF01510;,8.00E-30,CHOYP_PGRP-S2.1.2,3.00E-64,ruditapes2_c826,,,,,PGSC2_DROSI,Drosophila simulans (Fruit fly),innate immune response [GO:0045087]; peptidoglycan catabolic process [GO:0009253] comp119038_c0_seq1,864,45.6019,0.4700421,32,26,,,,,,,,,5.00E-38,CHOYP_LOC756678.2.2,1.00E-68,ruditapes_c15646,,,,,,, comp119055_c1_seq1,867,33.3333,0.26642147,27,109,,4.00E-13,Q8NHY6,Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6),Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP28_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp119057_c0_seq1,496,46.9758,0.63862693,19,19,,,,,,,,,2.00E-58,CHOYP_LOC100367618.1.1,,,,,,,,, comp119057_c1_seq1,415,43.3735,0.325893,15,30,,8.00E-52,P42695,Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3),Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3),GO:0051301; GO:0035064; GO:0007076; GO:0031618; GO:0000799,cell division; methylated histone residue binding; mitotic chromosome condensation; nuclear centromeric heterochromatin; nuclear condensin complex,PF12717;,,,,,,,,,CNDD3_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076] comp119070_c0_seq1,447,32.4385,0.08592295,9,73,,6.00E-23,P13360,Protein glass,Protein glass,GO:0003677; GO:0003705; GO:0001752; GO:0043153; GO:0046872; GO:0005634; GO:0045944; GO:0010114; GO:0035271; GO:0007605; GO:0007601,DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; compound eye photoreceptor fate commitment; entrainment of circadian clock by photoperiod; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to red light; ring gland development; sensory perception of sound; visual perception,PF00096;,,,,,,,,,GLAS_DROME,Drosophila melanogaster (Fruit fly),"circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp119077_c0_seq1,492,44.9187,0.55954483,25,11,,4.00E-67,A1ZAJ2,Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104),Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104),GO:0005524; GO:0048490; GO:0007411; GO:0005737; GO:0005871; GO:0008345; GO:0005874; GO:0005875; GO:0003777; GO:0007528; GO:0005543; GO:0016188; GO:0047496,ATP binding; anterograde synaptic vesicle transport; axon guidance; cytoplasm; kinesin complex; larval locomotory behavior; microtubule; microtubule associated complex; microtubule motor activity; neuromuscular junction development; phospholipid binding; synaptic vesicle maturation; vesicle transport along microtubule,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,1.00E-69,CHOYP_KIF1A.1.1,,,,,,,KIF1A_DROME,Drosophila melanogaster (Fruit fly),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; axo-dendritic transport [GO:0008088]; axon guidance [GO:0007411]; filopodium assembly [GO:0046847]; larval locomotory behavior [GO:0008345]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuromuscular junction development [GO:0007528]; positive regulation of insulin secretion [GO:0032024]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotion [GO:0040012]; regulation of synapse assembly [GO:0051963]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192]; vesicle transport along microtubule [GO:0047496] comp119082_c0_seq1,491,44.8065,0.65106547,9,38,,8.00E-76,Q17R14,Unconventional myosin-Id,Unconventional myosin-Id,GO:0005524; GO:0003774; GO:0016459; GO:0010923,ATP binding; motor activity; myosin complex; negative regulation of phosphatase activity,PF00612;PF00063;PF06017;,7.00E-78,CHOYP_LOC373223.1.1,,,,,,,MYO1D_BOVIN,Bos taurus (Bovine),cellular localization [GO:0051641]; early endosome to recycling endosome transport [GO:0061502]; negative regulation of phosphatase activity [GO:0010923] comp119082_c1_seq1,318,43.3962,0.53613976,4,0,,2.00E-25,P54695,Myosin IF heavy chain,Myosin IF heavy chain,GO:0005524; GO:0003774; GO:0016459,ATP binding; motor activity; myosin complex,PF00612;PF00063;PF06017;,,,,,,,,,MYOF_DICDI,Dictyostelium discoideum (Slime mold), comp119082_c2_seq1,250,42.4,0.27603081,1,29,,9.00E-17,Q875Q8,Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2),Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2),GO:0005524; GO:0007049; GO:0003774; GO:0016459; GO:0015031,ATP binding; cell cycle; motor activity; myosin complex; protein transport,PF01843;PF00063;,7.00E-17,CHOYP_MYO1C.2.3,,,,,,,MYO2_LACK1,Lachancea kluyveri (strain ATCC 58438 / CBS 3082 / CCRC 21498 / NBRC 1685 / JCM 7257 / NCYC 543 / NRRL Y-12651) (Yeast) (Saccharomyces kluyveri),cell cycle [GO:0007049]; protein transport [GO:0015031] comp119082_c3_seq1,442,46.8326,0.50360243,2,32,,3.00E-19,Q1EG27,Myosin-IIIb (EC 2.7.11.1),Myosin-IIIb (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0032433; GO:0000146; GO:0016459; GO:0018105; GO:0018107; GO:0001917; GO:0001750; GO:0051491; GO:0046777; GO:0004674; GO:0050896; GO:0032426; GO:0007601,ATP binding; cytoplasm; filopodium tip; microfilament motor activity; myosin complex; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; photoreceptor inner segment; photoreceptor outer segment; positive regulation of filopodium assembly; protein autophosphorylation; protein serine/threonine kinase activity; response to stimulus; stereocilium bundle tip; visual perception,PF00612;PF00063;PF00069;,7.00E-14,CHOYP_ISCW_ISCW018858.1.1,,,,,,,MYO3B_MOUSE,Mus musculus (Mouse),peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp119093_c1_seq1,233,34.7639,0.65455751,4,0,,,,,,,,,6.00E-11,CHOYP_contig_040603,,,,,,,,, comp119120_c0_seq2,1088,37.4081,0.61230678,18,29,,3.00E-121,O15194,CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3),CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3),GO:0016311; GO:0046872; GO:0005634; GO:0004721,dephosphorylation; metal ion binding; nucleus; phosphoprotein phosphatase activity,PF03031;,2.00E-102,CHOYP_LOC100141993.1.1,,,,,,,CTDSL_HUMAN,Homo sapiens (Human),negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933] comp119120_c0_seq3,701,39.6576,0.77601885,0,8,,,,,,,,,,,1.00E-130,ruditapes2_c1443,,,,,,, comp119128_c0_seq2,499,49.499,0.99920465,4,13,,6.00E-35,P06602,Segmentation protein even-skipped,Segmentation protein even-skipped,GO:0000980; GO:0003705; GO:0007512; GO:0008595; GO:0001709; GO:0007417; GO:0007376; GO:0007377; GO:0003007; GO:0008045; GO:0007517; GO:0009997; GO:0000122; GO:0005634; GO:0007366; GO:0045944; GO:0035289; GO:0050770; GO:1901739; GO:0035290,"RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; adult heart development; anterior/posterior axis specification, embryo; cell fate determination; central nervous system development; cephalic furrow formation; germ-band extension; heart morphogenesis; motor neuron axon guidance; muscle organ development; negative regulation of cardioblast cell fate specification; negative regulation of transcription from RNA polymerase II promoter; nucleus; periodic partitioning by pair rule gene; positive regulation of transcription from RNA polymerase II promoter; posterior head segmentation; regulation of axonogenesis; regulation of myoblast fusion; trunk segmentation",PF00046;,8.00E-46,CHOYP_HOX3.1.1,,,,,,,EVE_DROME,Drosophila melanogaster (Fruit fly),"adult heart development [GO:0007512]; anterior/posterior axis specification, embryo [GO:0008595]; blastoderm segmentation [GO:0007350]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; cephalic furrow formation [GO:0007376]; germ-band extension [GO:0007377]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517]; negative regulation of cardioblast cell fate specification [GO:0009997]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; periodic partitioning by pair rule gene [GO:0007366]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; posterior head segmentation [GO:0035289]; regulation of axonogenesis [GO:0050770]; regulation of myoblast fusion [GO:1901739]; transcription, DNA-templated [GO:0006351]; trunk segmentation [GO:0035290]" comp119137_c0_seq1,1104,40.1268,1.03667078,4,193,,3.00E-19,Q9JHI0,Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI),Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI),GO:0031225; GO:0001525; GO:0005509; GO:0030154; GO:0030574; GO:0004222; GO:0005886; GO:0005578; GO:0006508; GO:0008270,anchored to membrane; angiogenesis; calcium ion binding; cell differentiation; collagen catabolic process; metalloendopeptidase activity; plasma membrane; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF00045;PF00413;PF01471;,,,,,,,,,MMP19_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; response to cAMP [GO:0051591]; response to hormone [GO:0009725] comp119141_c0_seq1,1634,41.2485,1.14022818,0,0,,7.00E-49,P59055,Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2),Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2),GO:0001228; GO:0006915; GO:0010923; GO:0005634; GO:0043065; GO:0043565,RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; apoptotic process; negative regulation of phosphatase activity; nucleus; positive regulation of apoptotic process; sequence-specific DNA binding,PF16019;,,,,,,,,,CSRN3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp119141_c0_seq2,1410,41.9149,1.08428967,0,0,,2.00E-49,P59055,Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2),Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2),GO:0001228; GO:0006915; GO:0010923; GO:0005634; GO:0043065; GO:0043565,RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; apoptotic process; negative regulation of phosphatase activity; nucleus; positive regulation of apoptotic process; sequence-specific DNA binding,PF16019;,2.00E-15,CHOYP_LOC101155731.1.1,,,,,,,CSRN3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp119144_c0_seq2,523,45.8891,0.59276235,1,6,,1.00E-55,Q8K2X2,RNA-binding protein 48,RNA-binding protein 48,GO:0003723; GO:0005634,RNA binding; nucleus,,2.00E-15,CHOYP_LOC100366729.1.1,,,,,,,RBM48_MOUSE,Mus musculus (Mouse), comp119145_c2_seq1,337,45.1039,0.59549503,11,0,,2.00E-18,P70545,Solute carrier family 13 member 2 (Intestinal sodium/dicarboxylate cotransporter) (Na(+)/dicarboxylate cotransporter 1) (NaDC-1),Solute carrier family 13 member 2 (Intestinal sodium/dicarboxylate cotransporter) (Na(+)/dicarboxylate cotransporter 1) (NaDC-1),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00939;,,,,,,,,,S13A2_RAT,Rattus norvegicus (Rat), comp119154_c0_seq1,1027,45.5696,0.32014979,3,49,,2.00E-28,Q9LJN4,Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),GO:0005975; GO:0005618; GO:0004553; GO:0005578,"carbohydrate metabolic process; cell wall; hydrolase activity, hydrolyzing O-glycosyl compounds; proteinaceous extracellular matrix",PF14310;PF00933;PF01915;,,,,,,,,,BXL5_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975] comp119154_c0_seq2,874,45.4233,0.33465113,0,0,,7.00E-29,Q9LJN4,Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),GO:0005975; GO:0005618; GO:0004553; GO:0005578,"carbohydrate metabolic process; cell wall; hydrolase activity, hydrolyzing O-glycosyl compounds; proteinaceous extracellular matrix",PF14310;PF00933;PF01915;,7.00E-18,CHOYP_LOC100375395.1.2,,,,,,,BXL5_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975] comp119161_c0_seq1,454,42.7313,0.6984683,33,13,,1.00E-63,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,2.00E-98,CHOYP_UBP24.1.1,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp119163_c0_seq1,533,45.9662,0.43151667,21,5,,2.00E-06,A4IIK1,Malignant fibrous histiocytoma-amplified sequence 1 homolog,Malignant fibrous histiocytoma-amplified sequence 1 homolog,GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF16095;PF13855;PF08477;,,,,,,,,,MFHA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),small GTPase mediated signal transduction [GO:0007264] comp11916_c0_seq1,201,45.7711,0.57715714,3,0,,2.00E-13,O60733,85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9),85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9),GO:0038096; GO:0047499; GO:0035965; GO:0032049; GO:0008219; GO:0005813; GO:0006935; GO:0005829; GO:0007204; GO:0045087; GO:0016042; GO:0060135; GO:0016020; GO:0007613; GO:0005739; GO:0051967; GO:0036151; GO:0036152; GO:0004623; GO:0090238; GO:2000304; GO:0045921; GO:0035774; GO:0090037; GO:0001934; GO:0090200; GO:0045909; GO:1901339; GO:0034976; GO:0014832,"Fc-gamma receptor signaling pathway involved in phagocytosis; calcium-independent phospholipase A2 activity; cardiolipin acyl-chain remodeling; cardiolipin biosynthetic process; cell death; centrosome; chemotaxis; cytosol; elevation of cytosolic calcium ion concentration; innate immune response; lipid catabolic process; maternal process involved in female pregnancy; membrane; memory; mitochondrion; negative regulation of synaptic transmission, glutamatergic; phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; phospholipase A2 activity; positive regulation of arachidonic acid secretion; positive regulation of ceramide biosynthetic process; positive regulation of exocytosis; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of protein kinase C signaling cascade; positive regulation of protein phosphorylation; positive regulation of release of cytochrome c from mitochondria; positive regulation of vasodilation; regulation of store-operated calcium channel activity; response to endoplasmic reticulum stress; urinary bladder smooth muscle contraction",PF12796;PF01734;,4.00E-12,CHOYP_LOC100121363.1.1,,,,,,,PLPL9_HUMAN,Homo sapiens (Human),"antibacterial humoral response [GO:0019731]; cardiolipin biosynthetic process [GO:0032049]; chemotaxis [GO:0006935]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lipid catabolic process [GO:0016042]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasodilation [GO:0045909]; regulation of store-operated calcium channel activity [GO:1901339]; response to endoplasmic reticulum stress [GO:0034976]; urinary bladder smooth muscle contraction [GO:0014832]" comp119177_c0_seq1,250,34.4,0.41080854,9,0,,8.00E-07,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,4.00E-11,ruditapes2_c2681,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp119180_c0_seq1,927,43.0421,0.69984998,6,254,,1.00E-41,H2A0M7,Peroxidase-like protein,Peroxidase-like protein,GO:0005576; GO:0020037; GO:0004601; GO:0006979,extracellular region; heme binding; peroxidase activity; response to oxidative stress,PF03098;,,,,,,,,,PLSP_PINMG,Pinctada margaritifera (Black-lipped pearl oyster),response to oxidative stress [GO:0006979] comp119181_c0_seq3,318,47.4843,0.61626883,1,0,,5.00E-06,Q28066,C4b-binding protein beta chain,C4b-binding protein beta chain,GO:0006958; GO:0005576; GO:0045087,"complement activation, classical pathway; extracellular region; innate immune response",PF00084;,,,,,,,,,C4BPB_BOVIN,Bos taurus (Bovine),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]" comp119201_c0_seq1,620,39.5161,0.29888692,38,3,,1.00E-28,Q6AYA6,Uncharacterized protein C17orf62 homolog,Uncharacterized protein C17orf62 homolog,GO:0016021,integral to membrane,PF15169;,,,,,,,,,CQ062_RAT,Rattus norvegicus (Rat), comp119211_c0_seq1,409,43.5208,0.38160047,3,0,,5.00E-23,Q92J08,2Fe-2S ferredoxin (Adrenodoxin-like protein),2Fe-2S ferredoxin (Adrenodoxin-like protein),GO:0051537; GO:0009055; GO:0046872; GO:0055114,"2 iron, 2 sulfur cluster binding; electron carrier activity; metal ion binding; oxidation-reduction process",PF00111;,1.00E-30,CHOYP_DANA_GF25062.1.1,,,,,,,FER2_RICCN,Rickettsia conorii (strain ATCC VR-613 / Malish 7),oxidation-reduction process [GO:0055114] comp119211_c0_seq2,543,43.6464,0.63063538,12,30,,2.00E-33,P00257,"Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepato-ferredoxin)","Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepato-ferredoxin)",GO:0051537; GO:0008203; GO:0009055; GO:0042446; GO:0046872; GO:0005759; GO:0005739; GO:0055114; GO:0008022; GO:0042803; GO:0006694,"2 iron, 2 sulfur cluster binding; cholesterol metabolic process; electron carrier activity; hormone biosynthetic process; metal ion binding; mitochondrial matrix; mitochondrion; oxidation-reduction process; protein C-terminus binding; protein homodimerization activity; steroid biosynthetic process",PF00111;,1.00E-44,CHOYP_LOC100748436.1.1,,,,,,,ADX_BOVIN,Bos taurus (Bovine),cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694] comp119219_c0_seq1,275,36.3636,1.32534766,7,20,,6.00E-08,A8Y1P7,"Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)","Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)",GO:0016021; GO:0046872; GO:0006486; GO:0016757,"integral to membrane; metal ion binding; protein glycosylation; transferase activity, transferring glycosyl groups",PF02709;PF13733;,,,,,,,,,BRE4_CAEBR,Caenorhabditis briggsae,protein glycosylation [GO:0006486] comp119220_c0_seq1,1318,41.5781,0.54606068,35,46,,2.00E-65,Q96M89,Coiled-coil domain-containing protein 138,Coiled-coil domain-containing protein 138,,,,9.00E-88,CHOYP_LOC100371694.1.1,3.00E-117,ruditapes_c28165,,,,,CC138_HUMAN,Homo sapiens (Human), comp119223_c0_seq2,343,34.9854,1.14955029,11,6,,,,,,,,,,,4.00E-13,ruditapes_c11474,,,,,,, comp119226_c0_seq1,1098,46.9945,0.64406196,39,50,,,,,,,,,,,4.00E-57,ruditapes_c30755,,,,,,, comp119228_c0_seq1,483,43.4783,0.70650791,10,21,,1.00E-26,Q9NYQ7,Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_HUMAN,Homo sapiens (Human),"axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp119228_c1_seq1,467,41.3276,0.85438536,12,34,,3.00E-24,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp119230_c0_seq3,586,39.0785,0.83001027,0,7,,1.00E-47,P27718,Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC),Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC),GO:0004058; GO:0006520; GO:0042416; GO:0030170,aromatic-L-amino-acid decarboxylase activity; cellular amino acid metabolic process; dopamine biosynthetic process; pyridoxal phosphate binding,PF00282;,,,,,,,,,DDC_BOVIN,Bos taurus (Bovine),cellular amino acid metabolic process [GO:0006520]; dopamine biosynthetic process [GO:0042416] comp119230_c0_seq4,510,42.7451,0.99443107,0,0,,5.00E-21,P81893,Alpha-methyldopa hypersensitive protein (EC 4.1.1.-) (Fragment),Alpha-methyldopa hypersensitive protein (EC 4.1.1.-) (Fragment),GO:0016831; GO:0006584; GO:0006520; GO:0040003; GO:0030170; GO:0042302,carboxy-lyase activity; catecholamine metabolic process; cellular amino acid metabolic process; chitin-based cuticle development; pyridoxal phosphate binding; structural constituent of cuticle,PF00282;,,,,,,,,,L2AM_DROSI,Drosophila simulans (Fruit fly),catecholamine metabolic process [GO:0006584]; cellular amino acid metabolic process [GO:0006520]; chitin-based cuticle development [GO:0040003] comp119233_c0_seq2,861,45.8769,0.57590786,0,0,,4.00E-21,Q8CIQ7,Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP),Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP),GO:0005737; GO:0005085; GO:0007264,cytoplasm; guanyl-nucleotide exchange factor activity; small GTPase mediated signal transduction,PF06920;PF14429;PF16172;PF07653;,,,,,,,,,DOCK3_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp119233_c0_seq5,999,46.2462,0.56645513,0,0,,3.00E-24,Q8N1I0,Dedicator of cytokinesis protein 4,Dedicator of cytokinesis protein 4,GO:0030675; GO:0048365; GO:0060326; GO:0005829; GO:0012505; GO:0005085; GO:0016020; GO:0007264; GO:0032420,Rac GTPase activator activity; Rac GTPase binding; cell chemotaxis; cytosol; endomembrane system; guanyl-nucleotide exchange factor activity; membrane; small GTPase mediated signal transduction; stereocilium,PF06920;PF14429;PF16172;PF07653;,,,,,,,,,DOCK4_HUMAN,Homo sapiens (Human),cell chemotaxis [GO:0060326]; negative regulation of vascular smooth muscle contraction [GO:1904694]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; small GTPase mediated signal transduction [GO:0007264] comp119233_c1_seq1,564,43.7943,0.37636676,21,10,,,,,,,,,4.00E-25,CHOYP_DOCK3.2.2,,,,,,,,, comp119234_c1_seq4,847,38.1346,0.6711525,0,15,,4.00E-53,P29372,DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase),DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase),GO:0006307; GO:0008725; GO:0052822; GO:0052821; GO:0043916; GO:0003684; GO:0045007; GO:0005654,DNA dealkylation involved in DNA repair; DNA-3-methyladenine glycosylase activity; DNA-3-methylguanine glycosylase activity; DNA-7-methyladenine glycosylase activity; DNA-7-methylguanine glycosylase activity; damaged DNA binding; depurination; nucleoplasm,PF02245;,6.00E-18,CHOYP_LOC100373361.1.1,,,,,,,3MG_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; depurination [GO:0045007]; DNA dealkylation involved in DNA repair [GO:0006307] comp119242_c1_seq1,849,45.2297,0.49065489,47,38,,5.00E-153,Q05B17,WD repeat-containing protein 48 (USP1-associated factor 1),WD repeat-containing protein 48 (USP1-associated factor 1),GO:0005764; GO:0005634; GO:0016579,lysosome; nucleus; protein deubiquitination,PF11816;PF00400;,5.00E-83,CHOYP_WDR48.1.2,,,,,,,WDR48_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein deubiquitination [GO:0016579] comp119254_c0_seq1,956,36.0879,0.58302372,25,195,,5.00E-28,Q969V5,Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 6.3.2.-) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (MAPL) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218),Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 6.3.2.-) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (MAPL) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218),GO:0019789; GO:0007257; GO:0006919; GO:0031307; GO:0000266; GO:0051646; GO:0030308; GO:0010637; GO:0005634; GO:0005777; GO:0043123; GO:0090141; GO:0033235; GO:0050821; GO:0016925; GO:1901028; GO:0004871; GO:0004842; GO:0008270,SUMO ligase activity; activation of JUN kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; integral to mitochondrial outer membrane; mitochondrial fission; mitochondrion localization; negative regulation of cell growth; negative regulation of mitochondrial fusion; nucleus; peroxisome; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of mitochondrial fission; positive regulation of protein sumoylation; protein stabilization; protein sumoylation; regulation of mitochondrial outer membrane permeabilization; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF12483;,,,,,,,,,MUL1_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; negative regulation of cell growth [GO:0030308]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of innate immune response [GO:0045824]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of dendrite extension [GO:1903861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein sumoylation [GO:0033235]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901028]; regulation of mitochondrion organization [GO:0010821] comp119257_c0_seq1,601,44.7587,0.77102341,5,71,,7.00E-68,P47990,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0030151; GO:0043546; GO:0005777; GO:0034418; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; peroxisome; urate biosynthetic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_CHICK,Gallus gallus (Chicken),urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] comp119261_c0_seq1,870,41.0345,0.32896934,60,0,,3.00E-15,Q9BTT6,Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein),Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein),GO:0005737; GO:0016020,cytoplasm; membrane,PF13855;,,,,,,,,,LRRC1_HUMAN,Homo sapiens (Human), comp119263_c0_seq1,635,37.4803,0.58801085,15,45,,4.00E-36,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,,,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp119272_c0_seq1,283,49.47,0.46405808,0,0,,4.00E-07,A7SNN5,Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4),Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4),GO:0005524; GO:0005814; GO:0018108; GO:0004674; GO:0004713,ATP binding; centriole; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;,,,,,,,,,PLK4_NEMVE,Nematostella vectensis (Starlet sea anemone), comp119272_c0_seq2,778,42.545,0.48424096,20,32,,1.00E-12,Q63638,Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),GO:0005524; GO:0042692; GO:0005634; GO:0004674,ATP binding; muscle cell differentiation; nucleus; protein serine/threonine kinase activity,PF07679;PF00069;,,,,,,,,,SPEG_RAT,Rattus norvegicus (Rat),muscle cell differentiation [GO:0042692] comp119278_c0_seq2,766,41.906,0.60742956,15,0,,4.00E-152,O35303,Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein),Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein),GO:0005525; GO:0003924; GO:0005794; GO:0005829; GO:0003374; GO:0012505; GO:0090149; GO:0005874; GO:0000266; GO:0043653; GO:0005741; GO:0005739; GO:0070584; GO:0048471; GO:0005777; GO:0016559; GO:2001244; GO:0050714; GO:0090200; GO:0042803; GO:0051289; GO:1900063,GTP binding; GTPase activity; Golgi apparatus; cytosol; dynamin polymerization involved in mitochondrial fission; endomembrane system; membrane fission involved in mitochondrial fission; microtubule; mitochondrial fission; mitochondrial fragmentation involved in apoptotic process; mitochondrial outer membrane; mitochondrion; mitochondrion morphogenesis; perinuclear region of cytoplasm; peroxisome; peroxisome fission; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of protein secretion; positive regulation of release of cytochrome c from mitochondria; protein homodimerization activity; protein homotetramerization; regulation of peroxisome organization,PF01031;PF00350;PF02212;,4.00E-134,CHOYP_LOC100646574.1.1,,,,,,,DNM1L_RAT,Rattus norvegicus (Rat),dynamin polymerization involved in mitochondrial fission [GO:0003374]; endocytosis [GO:0006897]; heart contraction [GO:0060047]; membrane fusion [GO:0061025]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial membrane fission [GO:0090149]; mitochondrion morphogenesis [GO:0070584]; necroptotic process [GO:0070266]; peroxisome fission [GO:0016559]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein homotetramerization [GO:0051289]; protein localization to mitochondrion [GO:0070585]; regulation of ATP metabolic process [GO:1903578]; regulation of mitophagy [GO:1903146]; regulation of peroxisome organization [GO:1900063]; regulation of protein oligomerization [GO:0032459]; release of cytochrome c from mitochondria [GO:0001836] comp119282_c0_seq1,558,38.172,0.6424172,16,13,,2.00E-24,Q8BTI9,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)",GO:0016303; GO:0035005; GO:0005524; GO:0006914; GO:0006874; GO:0040016; GO:0006897; GO:0007156; GO:0005634; GO:0005942; GO:0046934; GO:0048015; GO:0005886; GO:0030168; GO:0001952,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; autophagy; cellular calcium ion homeostasis; embryonic cleavage; endocytosis; homophilic cell adhesion; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; phosphatidylinositol-mediated signaling; plasma membrane; platelet activation; regulation of cell-matrix adhesion",PF00454;PF00792;PF02192;PF00794;PF00613;,3.00E-13,CHOYP_PK3CD.1.1,,,,,,,PK3CB_MOUSE,Mus musculus (Mouse),angiogenesis involved in wound healing [GO:0060055]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; embryonic cleavage [GO:0040016]; endocytosis [GO:0006897]; endothelial cell proliferation [GO:0001935]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of gene expression [GO:0010628]; regulation of cell-matrix adhesion [GO:0001952]; response to wounding [GO:0009611] comp119283_c0_seq1,1290,48.5271,0.50175436,50,21,,3.00E-60,O44997,Death-associated protein kinase dapk-1 (EC 2.7.11.1),Death-associated protein kinase dapk-1 (EC 2.7.11.1),GO:0005524; GO:0045087; GO:0046872; GO:0007275; GO:0004674; GO:0007165,ATP binding; innate immune response; metal ion binding; multicellular organismal development; protein serine/threonine kinase activity; signal transduction,PF12796;PF00531;PF00069;,,,,,,,,,DAPK_CAEEL,Caenorhabditis elegans,innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165] comp119283_c1_seq1,358,48.324,0.25417927,0,0,,9.00E-19,Q9WV06,Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp),Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp),GO:0031674; GO:0005634; GO:0035914,I band; nucleus; skeletal muscle cell differentiation,PF00023;PF12796;,,,,,,,,,ANKR2_MOUSE,Mus musculus (Mouse),negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to muscle stretch [GO:0035994]; skeletal muscle cell differentiation [GO:0035914] comp119283_c1_seq2,334,45.8084,0.24668851,3,0,,1.00E-12,Q86U10,60 kDa lysophospholipase (EC 3.1.1.5) [Includes: L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase); Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47)],60 kDa lysophospholipase (EC 3.1.1.5) [Includes: L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase); Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47)],GO:0003847; GO:0004067; GO:0006528; GO:0016042; GO:0004622; GO:0006644,1-alkyl-2-acetylglycerophosphocholine esterase activity; asparaginase activity; asparagine metabolic process; lipid catabolic process; lysophospholipase activity; phospholipid metabolic process,PF12796;PF00710;,,,,,,,,,LPP60_HUMAN,Homo sapiens (Human),cellular amino acid biosynthetic process [GO:0008652]; lipid catabolic process [GO:0016042] comp119284_c0_seq2,629,39.9046,0.20443977,13,33,,2.00E-29,Q6PCS6,Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18),Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18),GO:0006915; GO:0016021; GO:0000266; GO:0005743,apoptotic process; integral to membrane; mitochondrial fission; mitochondrial inner membrane,PF10558;,1.00E-12,CHOYP_LOC100375189.1.1,,,,,,,MTFP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; mitochondrial fission [GO:0000266] comp119291_c0_seq2,360,45.2778,0.49740127,5,3,,1.00E-22,Q9Y251,Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit],Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit],GO:0004566; GO:0005975; GO:0007160; GO:0005576; GO:0006027; GO:0030200; GO:0030305; GO:0043202; GO:0005765; GO:0045121; GO:0005634; GO:0030194; GO:0051798; GO:0033690; GO:0051897; GO:0010575; GO:0046983; GO:0051797; GO:0045545; GO:0061042,beta-glucuronidase activity; carbohydrate metabolic process; cell-matrix adhesion; extracellular region; glycosaminoglycan catabolic process; heparan sulfate proteoglycan catabolic process; heparanase activity; lysosomal lumen; lysosomal membrane; membrane raft; nucleus; positive regulation of blood coagulation; positive regulation of hair follicle development; positive regulation of osteoblast proliferation; positive regulation of protein kinase B signaling cascade; positive regulation vascular endothelial growth factor production; protein dimerization activity; regulation of hair follicle development; syndecan binding; vascular wound healing,PF03662;,,,,,,,,,HPSE_HUMAN,Homo sapiens (Human),angiogenesis involved in wound healing [GO:0060055]; carbohydrate metabolic process [GO:0005975]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; positive regulation of blood coagulation [GO:0030194]; positive regulation of hair follicle development [GO:0051798]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor production [GO:0010575]; proteoglycan metabolic process [GO:0006029]; regulation of hair follicle development [GO:0051797]; vascular wound healing [GO:0061042] comp119296_c0_seq1,667,43.7781,0.76506972,3,49,,9.00E-19,Q60041,"Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)","Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)",GO:0031176; GO:0045493,"endo-1,4-beta-xylanase activity; xylan catabolic process",PF00331;,,,,,,,,,XYNB_THENE,Thermotoga neapolitana,xylan catabolic process [GO:0045493] comp119301_c0_seq1,322,47.8261,1.17252643,0,29,,3.00E-20,D3ZTX0,Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27),Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27),GO:0030663; GO:0012507; GO:0005794; GO:0005783; GO:0005789; GO:0005793; GO:0033116; GO:0016021; GO:0015031,COPI-coated vesicle membrane; ER to Golgi transport vesicle membrane; Golgi apparatus; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; protein transport,PF01105;,,,,,,,,,TMED7_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp119303_c0_seq1,1194,39.7822,0.32066212,37,77,,1.00E-92,Q9W4E2,Neurobeachin (A-kinase anchor protein 550) (AKAP 550) (Protein rugose) (dAKAP550),Neurobeachin (A-kinase anchor protein 550) (AKAP 550) (Protein rugose) (dAKAP550),GO:0042675; GO:0005737; GO:0042462; GO:0016021; GO:0016319; GO:0007528; GO:0043025; GO:0008355; GO:0051018,compound eye cone cell differentiation; cytoplasm; eye photoreceptor cell development; integral to membrane; mushroom body development; neuromuscular junction development; neuronal cell body; olfactory learning; protein kinase A binding,PF02138;PF06469;PF15787;PF14844;PF00400;,1.00E-111,CHOYP_LOC724172.1.1,,,,,,,NBEA_DROME,Drosophila melanogaster (Fruit fly),compound eye cone cell differentiation [GO:0042675]; eye photoreceptor cell development [GO:0042462]; mushroom body development [GO:0016319]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; protein localization [GO:0008104]; short-term memory [GO:0007614] comp119304_c0_seq1,207,63.285,1.06669156,0,12,,6.00E-13,P0AFN9,Inner membrane transport permease YadH,Inner membrane transport permease YadH,GO:0005524; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF01061;,,,,,,,,,YADH_SHIFL,Shigella flexneri,transport [GO:0006810] comp119307_c0_seq1,293,44.0273,0.4240434,10,7,,1.00E-32,Q9Y5Q9,General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),GO:0042791; GO:0003677; GO:0005654; GO:0042797; GO:0000127,5S class rRNA transcription from RNA polymerase III type 1 promoter; DNA binding; nucleoplasm; tRNA transcription from RNA polymerase III promoter; transcription factor TFIIIC complex,PF13181;,,,,,,,,,TF3C3_HUMAN,Homo sapiens (Human),"5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]" comp119308_c0_seq2,468,36.1111,0.52563983,6,8,,,,,,,,,2.00E-14,CHOYP_NEMVEDRAFT_V1G125875.2.3,,,,,,,,, comp119308_c0_seq3,580,36.5517,0.41459404,19,0,,3.00E-26,Q0IH24,Sperm flagellar protein 1,Sperm flagellar protein 1,GO:0035085; GO:0005856,cilium axoneme; cytoskeleton,PF06294;,,,,,,,,,SPEF1_XENLA,Xenopus laevis (African clawed frog), comp119309_c0_seq1,419,42.0048,0.27121425,9,13,,7.00E-13,Q3T906,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0046835; GO:0030154; GO:0016021; GO:0005634; GO:0009306,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; carbohydrate phosphorylation; cell differentiation; integral to membrane; nucleus; protein secretion,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,,,,,,,,,GNPTA_HUMAN,Homo sapiens (Human),carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; protein secretion [GO:0009306] comp119325_c0_seq2,342,36.5497,0.53261325,4,7,,9.00E-23,Q5ZJY5,Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5),Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5),GO:0005524; GO:0016605; GO:0030915; GO:0051301; GO:0090398; GO:0000781; GO:0000724; GO:0007067; GO:0034184; GO:0045842; GO:0000722,"ATP binding; PML body; Smc5-Smc6 complex; cell division; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; mitosis; positive regulation of maintenance of mitotic sister chromatid cohesion; positive regulation of mitotic metaphase/anaphase transition; telomere maintenance via recombination",PF02463;,9.00E-18,CHOYP_SMC5.1.1,8.00E-35,ruditapes_c10327,,,,,SMC5_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722] comp119337_c1_seq1,272,45.5882,1.35503399,7,151,,,,,,,,,5.00E-51,CHOYP_LOC100501556.1.1,,,,,,,,, comp119342_c0_seq1,510,38.4314,0.1609793,24,20,,2.00E-07,Q14191,"Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)","Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)",GO:0043138; GO:0008408; GO:0005524; GO:0043140; GO:0004003; GO:0006310; GO:0000731; GO:0051880; GO:0000403; GO:0006284; GO:0000405; GO:0007569; GO:0071480; GO:0009267; GO:0005813; GO:0006302; GO:0009378; GO:0000287; GO:0030145; GO:0010259; GO:0005730; GO:0032066; GO:0005654; GO:0051345; GO:0032403; GO:0042803; GO:0042981; GO:0040009; GO:0031297; GO:0001302; GO:0010225; GO:0006979; GO:0000723,3'-5' DNA helicase activity; 3'-5' exonuclease activity; ATP binding; ATP-dependent 3'-5' DNA helicase activity; ATP-dependent DNA helicase activity; DNA recombination; DNA synthesis involved in DNA repair; G-quadruplex DNA binding; Y-form DNA binding; base-excision repair; bubble DNA binding; cell aging; cellular response to gamma radiation; cellular response to starvation; centrosome; double-strand break repair; four-way junction helicase activity; magnesium ion binding; manganese ion binding; multicellular organismal aging; nucleolus; nucleolus to nucleoplasm transport; nucleoplasm; positive regulation of hydrolase activity; protein complex binding; protein homodimerization activity; regulation of apoptotic process; regulation of growth rate; replication fork processing; replicative cell aging; response to UV-C; response to oxidative stress; telomere maintenance,PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;,,,,,,,,,WRN_HUMAN,Homo sapiens (Human),aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; protein sumoylation [GO:0016925]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp119371_c0_seq1,692,37.7168,0.38077003,19,75,,1.00E-10,Q9UBU6,Protein FAM8A1 (Autosomal highly conserved protein),Protein FAM8A1 (Autosomal highly conserved protein),GO:0016021,integral to membrane,PF06271;,,,,,,,,,FA8A1_HUMAN,Homo sapiens (Human), comp119376_c1_seq1,236,47.4576,0.7189209,2,19,,1.00E-06,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp119387_c0_seq1,590,40.339,0.97336477,9,55,,3.00E-35,Q6ZSB9,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp119388_c0_seq1,924,39.3939,0.43593742,35,32,,6.00E-47,Q8NCJ5,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,7.00E-69,CHOYP_SPRY3.1.1,,,,,,,SPRY3_HUMAN,Homo sapiens (Human), comp119392_c0_seq1,643,47.5894,0.54218493,7,77,,7.00E-27,Q03001,Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0009925; GO:0005604; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0031252; GO:0048870; GO:0016023; GO:0031122; GO:0005829; GO:0005789; GO:0030198; GO:0030056; GO:0031581; GO:0016021; GO:0007229; GO:0005882; GO:0045111; GO:0045104; GO:0030011; GO:0015630; GO:0000226; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0042803; GO:0031110; GO:0009611; GO:0008090,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; basal plasma membrane; basement membrane; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cell leading edge; cell motility; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; cytosol; endoplasmic reticulum membrane; extracellular matrix organization; hemidesmosome; hemidesmosome assembly; integral to membrane; integrin-mediated signaling pathway; intermediate filament; intermediate filament cytoskeleton; intermediate filament cytoskeleton organization; maintenance of cell polarity; microtubule cytoskeleton; microtubule cytoskeleton organization; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; response to wounding; retrograde axon cargo transport,PF00307;PF13499;PF02187;PF00681;PF00435;,2.00E-11,CHOYP_DYST.1.2,,,,,,,DYST_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611] comp119396_c0_seq1,943,46.4475,0.4345502,15,15,,7.00E-10,P41436,Apoptosis inhibitor IAP,Apoptosis inhibitor IAP,GO:0006915; GO:0008270,apoptotic process; zinc ion binding,PF00653;,,,,,,,,,IAP_GVCPM,Cydia pomonella granulosis virus (isolate Mexico/1963) (CpGV) (Cydia pomonella granulovirus), comp119413_c0_seq1,547,41.8647,0.59760287,1,4,,5.00E-10,Q6PDC0,RUN domain-containing protein 3B,RUN domain-containing protein 3B,,,PF02759;,,,,,,,,,RUN3B_MOUSE,Mus musculus (Mouse), comp119413_c0_seq2,536,42.3507,0.59619557,3,0,,3.00E-42,Q8BIJ7,RUN and FYVE domain-containing protein 1 (Rab4-interacting protein),RUN and FYVE domain-containing protein 1 (Rab4-interacting protein),GO:0005737; GO:0031901; GO:0006897; GO:0008289; GO:0046872; GO:0008565; GO:0030100,cytoplasm; early endosome membrane; endocytosis; lipid binding; metal ion binding; protein transporter activity; regulation of endocytosis,PF01363;PF02759;,3.00E-26,CHOYP_LOC100372467.1.1,,,,,,,RUFY1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100] comp119432_c0_seq1,1274,47.7237,0.65284218,62,43,,0,E1BNG3,Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0006307; GO:0008283; GO:0005737; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA dealkylation involved in DNA repair; cell proliferation; cytoplasm; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00270;PF00271;PF02889;,0,CHOYP_ASCC3.1.1,,,,,,,ASCC3_BOVIN,Bos taurus (Bovine),"cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp119440_c0_seq1,653,38.2848,0.63898538,20,135,,,,,,,,,1.00E-12,CHOYP_CBG10904.1.1,,,,,,,,, comp119443_c0_seq1,266,43.609,0.24876128,7,17,,1.00E-13,P50460,Cysteine and glycine-rich protein 2 (Beta-cysteine-rich protein) (Beta-CRP) (Cysteine-rich protein 2) (CRP2),Cysteine and glycine-rich protein 2 (Beta-cysteine-rich protein) (Beta-CRP) (Cysteine-rich protein 2) (CRP2),GO:0030154; GO:0007275; GO:0005634; GO:0008270,cell differentiation; multicellular organismal development; nucleus; zinc ion binding,PF00412;,5.00E-26,CHOYP_MLP2.4.4,,,,,,,CSRP2_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp119443_c1_seq1,465,47.3118,0.5846464,19,32,,1.00E-15,Q24400,Muscle LIM protein Mlp84B,Muscle LIM protein Mlp84B,GO:0030018; GO:0007517; GO:0060537; GO:0005634; GO:0090175; GO:0045214; GO:0008307; GO:0008270,Z disc; muscle organ development; muscle tissue development; nucleus; regulation of establishment of planar polarity; sarcomere organization; structural constituent of muscle; zinc ion binding,PF00412;,2.00E-21,CHOYP_MLP2.1.4,,,,,,,MLP2_DROME,Drosophila melanogaster (Fruit fly),cell differentiation [GO:0030154]; muscle tissue development [GO:0060537]; regulation of establishment of planar polarity [GO:0090175]; sarcomere organization [GO:0045214]; skeletal muscle tissue development [GO:0007519] comp119453_c0_seq1,1046,45.5067,0.46419493,12,2,,7.00E-125,Q6NYU2,Probable helicase with zinc finger domain (EC 3.6.4.-),Probable helicase with zinc finger domain (EC 3.6.4.-),GO:0005524; GO:0004386; GO:0046872; GO:0005634; GO:0003700,ATP binding; helicase activity; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity,PF00642;,8.00E-62,CHOYP_HELZ.2.2,,,,,,,HELZ_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp119453_c0_seq2,950,44.8421,0.46485121,3,0,,6.00E-33,Q99MV5,Putative helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1),RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog),GO:0005524; GO:0008283; GO:0005737; GO:0004386; GO:0007517; GO:0045786; GO:0007283,ATP binding; cell proliferation; cytoplasm; helicase activity; muscle organ development; negative regulation of cell cycle; spermatogenesis,,,,,,,,,,M10L1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp119463_c0_seq3,388,47.9381,0.60490832,3,0,,5.00E-49,P13631,Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3),Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3),GO:0003677; GO:0070384; GO:0009952; GO:0060070; GO:0071300; GO:0048048; GO:0035116; GO:0003430; GO:0016021; GO:0035264; GO:0061037; GO:0008285; GO:0032331; GO:0000122; GO:0005654; GO:0043065; GO:0008284; GO:0045944; GO:0060740; GO:0008361; GO:0031641; GO:0032526; GO:0003708; GO:0048384; GO:0046965; GO:0043565; GO:0003700; GO:0003707; GO:0060534; GO:0005667; GO:0006367; GO:0008270,DNA binding; Harderian gland development; anterior/posterior pattern specification; canonical Wnt receptor signaling pathway; cellular response to retinoic acid; embryonic eye morphogenesis; embryonic hindlimb morphogenesis; growth plate cartilage chondrocyte growth; integral to membrane; multicellular organism growth; negative regulation of cartilage development; negative regulation of cell proliferation; negative regulation of chondrocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; prostate gland epithelium morphogenesis; regulation of cell size; regulation of myelination; response to retinoic acid; retinoic acid receptor activity; retinoic acid receptor signaling pathway; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; trachea cartilage development; transcription factor complex; transcription initiation from RNA polymerase II promoter; zinc ion binding,PF00104;PF00105;,1.00E-66,CHOYP_RARB.3.3,,,,,,,RARG_HUMAN,Homo sapiens (Human),anterior/posterior pattern specification [GO:0009952]; canonical Wnt signaling pathway [GO:0060070]; cellular response to retinoic acid [GO:0071300]; embryonic camera-type eye development [GO:0031076]; embryonic eye morphogenesis [GO:0048048]; embryonic hindlimb morphogenesis [GO:0035116]; face development [GO:0060324]; glandular epithelial cell development [GO:0002068]; growth plate cartilage chondrocyte growth [GO:0003430]; Harderian gland development [GO:0070384]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of programmed cell death [GO:0043068]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland epithelium morphogenesis [GO:0060740]; regulation of cell size [GO:0008361]; regulation of myelination [GO:0031641]; regulation of myeloid cell differentiation [GO:0045637]; response to retinoic acid [GO:0032526]; retinal pigment epithelium development [GO:0003406]; retinoic acid receptor signaling pathway [GO:0048384]; trachea cartilage development [GO:0060534]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp119471_c0_seq1,892,42.4888,0.70716758,0,77,,2.00E-19,Q7DFU6,Putative uncharacterized protein YghX,Putative uncharacterized protein YghX,GO:0016787,hydrolase activity,PF01738;,,,2.00E-17,ruditapes_c11575,,,,,YGHX_ECOLI,Escherichia coli (strain K12), comp119489_c0_seq2,749,48.7316,0.42810868,12,48,,4.00E-26,P70206,Plexin-A1 (Plex 1) (Plexin-1),Plexin-A1 (Plex 1) (Plexin-1),GO:0060666; GO:0016021; GO:0005622; GO:0005886; GO:0014910; GO:0017154,dichotomous subdivision of terminal units involved in salivary gland branching; integral to membrane; intracellular; plasma membrane; regulation of smooth muscle cell migration; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA1_MOUSE,Mus musculus (Mouse),branchiomotor neuron axon guidance [GO:0021785]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of smooth muscle cell migration [GO:0014910]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp119492_c0_seq1,696,47.5575,0.76949298,26,33,,,,,,,,,9.00E-15,CHOYP_LOC585963.1.2,,,,,,,,, comp119500_c0_seq1,687,43.5226,0.90370696,11,86,,4.00E-47,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,6.00E-17,CHOYP_LOC100651467.2.2,,,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp119503_c1_seq1,539,30.7978,0,16,0,,,,,,,,,,,2.00E-12,ruditapes_c17260,,,,,,, comp119510_c0_seq1,531,40.3013,0.42548805,15,44,,,,,,,,,1.00E-11,CHOYP_BRAFLDRAFT_67258.1.18,,,,,,,,, comp119511_c0_seq1,354,44.6328,0.51400024,3,72,,6.00E-50,Q9CUS9,Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin-like protein 4),Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin-like protein 4),GO:0030660; GO:0042500; GO:0071458; GO:0071556; GO:0042803; GO:0006508; GO:0005791,"Golgi-associated vesicle membrane; aspartic endopeptidase activity, intramembrane cleaving; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; protein homodimerization activity; proteolysis; rough endoplasmic reticulum",PF04258;,4.00E-66,CHOYP_AAEL_AAEL004138.2.2,,,,,,,SPPL3_MOUSE,Mus musculus (Mouse),membrane protein proteolysis [GO:0033619]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; signal peptide processing [GO:0006465]; T cell receptor signaling pathway [GO:0050852] comp119515_c0_seq1,840,42.619,0.68416868,53,29,,5.00E-27,P81425,Dipeptidyl peptidase 4 (EC 3.4.14.5) (Activation molecule 3) (ACT3) (Adenosine deaminase complexing protein) (ADCP-I) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (WC10) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)],Dipeptidyl peptidase 4 (EC 3.4.14.5) (Activation molecule 3) (ACT3) (Adenosine deaminase complexing protein) (ADCP-I) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (WC10) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)],GO:0031295; GO:0004177; GO:0016324; GO:0007155; GO:0030054; GO:0009986; GO:0008239; GO:0030139; GO:0043542; GO:0005576; GO:0016021; GO:0071438; GO:0030027; GO:0031258; GO:0045121; GO:0010716; GO:0008284; GO:0002020; GO:0042803; GO:0006508; GO:0005102; GO:0004252,T cell costimulation; aminopeptidase activity; apical plasma membrane; cell adhesion; cell junction; cell surface; dipeptidyl-peptidase activity; endocytic vesicle; endothelial cell migration; extracellular region; integral to membrane; invadopodium membrane; lamellipodium; lamellipodium membrane; membrane raft; negative regulation of extracellular matrix disassembly; positive regulation of cell proliferation; protease binding; protein homodimerization activity; proteolysis; receptor binding; serine-type endopeptidase activity,PF00930;PF00326;,1.00E-46,CHOYP_BRAFLDRAFT_92908.1.1,,,,,,,DPP4_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell proliferation [GO:0008284]; T cell costimulation [GO:0031295] comp119515_c3_seq1,366,46.9945,0.34777571,7,15,,2.00E-09,P39839,Uncharacterized peptidase YuxL (EC 3.4.21.-),Uncharacterized peptidase YuxL (EC 3.4.21.-),GO:0006508; GO:0008236,proteolysis; serine-type peptidase activity,PF07676;PF00326;,,,,,,,,,YUXL_BACSU,Bacillus subtilis (strain 168), comp119515_c4_seq1,1127,43.8332,0.55797432,84,56,,1.00E-68,Q6V1X1,Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8),Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8),GO:0004177; GO:0005737; GO:0008239; GO:0006955; GO:0016020; GO:0005634; GO:0006508; GO:0008236,aminopeptidase activity; cytoplasm; dipeptidyl-peptidase activity; immune response; membrane; nucleus; proteolysis; serine-type peptidase activity,PF00930;PF00326;,5.00E-14,CHOYP_BRAFLDRAFT_92908.1.1,,,,,,,DPP8_HUMAN,Homo sapiens (Human),immune response [GO:0006955]; proteolysis [GO:0006508] comp119523_c0_seq1,454,46.2555,0.4952405,15,3,,3.00E-16,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,4.00E-42,CHOYP_LOC100695950.6.6,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp119523_c1_seq1,228,46.4912,0.32610097,6,0,,8.00E-19,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp119523_c2_seq1,464,43.1034,0.56363898,20,16,,1.00E-24,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,9.00E-45,CHOYP_contig_040048,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp119526_c0_seq2,416,39.6635,0.86489389,4,23,,3.00E-41,O16796,Neprilysin-2 (EC 3.4.24.-),Neprilysin-11 (EC 3.4.24.-),GO:0016021; GO:0046872; GO:0004222; GO:0006508,integral to membrane; metal ion binding; metalloendopeptidase activity; proteolysis,PF01431;PF05649;,,,,,,,,,NEPL2_CAEEL,Caenorhabditis elegans, comp119527_c0_seq3,696,41.2356,0.50777181,20,86,,3.00E-24,Q9JMA7,Cytochrome P450 3A41 (EC 1.14.14.1),Cytochrome P450 3A41 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP341_MOUSE,Mus musculus (Mouse),regulation of gene expression [GO:0010468] comp119529_c0_seq1,495,41.6162,0.60830437,3,4,,5.00E-54,Q32PV0,PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6),PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6),GO:0006915; GO:0005737; GO:0006909,apoptotic process; cytoplasm; phagocytosis,PF00640;,,,,,,,,,GULP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; phagocytosis [GO:0006909] comp119529_c0_seq2,419,42.4821,0.5835577,0,7,,7.00E-56,Q9UBP9,PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP),PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP),GO:0006915; GO:0005737; GO:0006869; GO:0006911; GO:0004871,"apoptotic process; cytoplasm; lipid transport; phagocytosis, engulfment; signal transducer activity",PF00640;,3.00E-50,CHOYP_GULP1.1.1,,,,,,,GULP1_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; lipid transport [GO:0006869]; phagocytosis, engulfment [GO:0006911]" comp119540_c0_seq2,259,47.1042,0.48925461,1,0,,1.00E-06,Q9Y5A7,NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18),NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18),GO:0005634; GO:0032436; GO:0016567; GO:0034341; GO:0034612; GO:0006511,nucleus; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; response to interferon-gamma; response to tumor necrosis factor; ubiquitin-dependent protein catabolic process,PF00627;,,,,,,,,,NUB1_HUMAN,Homo sapiens (Human),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; response to interferon-gamma [GO:0034341]; response to tumor necrosis factor [GO:0034612]; ubiquitin-dependent protein catabolic process [GO:0006511] comp119544_c0_seq1,490,41.6327,0.99144644,4,19,,7.00E-27,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,2.00E-22,CHOYP_HS12A.32.33,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp119544_c0_seq2,447,40.7159,1.02839708,0,10,,,,,,,,,3.00E-12,CHOYP_HSPA12A.16.27,,,,,,,,, comp119549_c0_seq1,575,47.6522,0.40204148,29,22,,4.00E-48,Q9UJW0,Dynactin subunit 4 (Dyn4) (Dynactin subunit p62),Dynactin subunit 4 (Dyn4) (Dynactin subunit p62),GO:0019886; GO:0005813; GO:0005829; GO:0005869; GO:0005634,antigen processing and presentation of exogenous peptide antigen via MHC class II; centrosome; cytosol; dynactin complex; nucleus,PF05502;,5.00E-36,CHOYP_DCTN4.1.1,,,,,,,DCTN4_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; ER to Golgi vesicle-mediated transport [GO:0006888]; nuclear migration [GO:0007097] comp119550_c0_seq1,1056,36.6477,1.01781507,0,452,,4.00E-09,P07911,"Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form]","Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form]",GO:0005794; GO:0031225; GO:0016324; GO:0016323; GO:0005509; GO:0006968; GO:0048878; GO:0060170; GO:0031410; GO:0007588; GO:0005615; GO:0019898; GO:0045121; GO:0072218; GO:0072221; GO:0072233; GO:0008285; GO:0072372; GO:2000021; GO:0010033; GO:0000922,Golgi apparatus; anchored to membrane; apical plasma membrane; basolateral plasma membrane; calcium ion binding; cellular defense response; chemical homeostasis; cilium membrane; cytoplasmic vesicle; excretion; extracellular space; extrinsic to membrane; membrane raft; metanephric ascending thin limb development; metanephric distal convoluted tubule development; metanephric thick ascending limb development; negative regulation of cell proliferation; primary cilium; regulation of ion homeostasis; response to organic substance; spindle pole,PF12947;PF07645;PF00100;,,,,,,,,,UROM_HUMAN,Homo sapiens (Human),cellular defense response [GO:0006968]; chemical homeostasis [GO:0048878]; excretion [GO:0007588]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; leukocyte cell-cell adhesion [GO:0007159]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; negative regulation of cell proliferation [GO:0008285]; neutrophil migration [GO:1990266]; regulation of ion homeostasis [GO:2000021]; response to organic substance [GO:0010033] comp119553_c0_seq1,202,43.5644,0.21516161,3,0,,4.00E-06,Q86JF2,BEACH domain-containing protein lvsB,BEACH domain-containing protein lvsB,GO:0009267; GO:0031154; GO:0005768; GO:0006887; GO:0016021; GO:0007041; GO:0005764; GO:0007040; GO:0045335; GO:0001845; GO:0006970,cellular response to starvation; culmination involved in sorocarp development; endosome; exocytosis; integral to membrane; lysosomal transport; lysosome; lysosome organization; phagocytic vesicle; phagolysosome assembly; response to osmotic stress,PF02138;PF14844;PF00400;,,,,,,,,,LVSB_DICDI,Dictyostelium discoideum (Slime mold),cellular response to starvation [GO:0009267]; culmination involved in sorocarp development [GO:0031154]; exocytosis [GO:0006887]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; phagolysosome assembly [GO:0001845]; response to osmotic stress [GO:0006970] comp119553_c1_seq2,857,47.958,0.38685387,6,0,,2.00E-83,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,,,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp119553_c1_seq3,673,49.4799,0.38979339,0,0,,,,,,,,,1.00E-70,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,,, comp119563_c0_seq1,598,43.4783,0.7447182,17,24,,2.00E-07,Q571J5,"Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3)","Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3)",GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,Z354C_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp119569_c0_seq1,906,47.351,0.30027846,37,10,,1.00E-76,Q499U8,Transmembrane and coiled-coil domain-containing protein 4,Transmembrane and coiled-coil domain-containing protein 4,GO:0016021,integral to membrane,PF05277;,2.00E-32,CHOYP_TMCO4.1.1,,,,,,,TMCO4_RAT,Rattus norvegicus (Rat), comp119573_c0_seq1,1403,36.2794,0.57898773,889,4218,,1.00E-110,O18404,3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Scully protein) (Type II HADH),3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Scully protein) (Type II HADH),GO:0047015; GO:0003857; GO:0047022; GO:0018454; GO:0006637; GO:0008209; GO:0005829; GO:0008205; GO:0004303; GO:0008210; GO:0006631; GO:0005811; GO:0005875; GO:0005739; GO:0008033; GO:0047035; GO:0030283,3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; 3-hydroxyacyl-CoA dehydrogenase activity; 7-beta-hydroxysteroid dehydrogenase (NADP+) activity; acetoacetyl-CoA reductase activity; acyl-CoA metabolic process; androgen metabolic process; cytosol; ecdysone metabolic process; estradiol 17-beta-dehydrogenase activity; estrogen metabolic process; fatty acid metabolic process; lipid particle; microtubule associated complex; mitochondrion; tRNA processing; testosterone dehydrogenase (NAD+) activity; testosterone dehydrogenase [NAD(P)] activity,PF00106;,,,1.00E-46,ruditapes_c7226,,,,,HCD2_DROME,Drosophila melanogaster (Fruit fly),acyl-CoA metabolic process [GO:0006637]; androgen metabolic process [GO:0008209]; ecdysone metabolic process [GO:0008205]; estrogen metabolic process [GO:0008210]; fatty acid metabolic process [GO:0006631]; steroid metabolic process [GO:0008202]; tRNA processing [GO:0008033] comp119588_c0_seq1,813,39.8524,1.12177178,17,108,,7.00E-16,Q13219,Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A),Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A),GO:0030154; GO:0044267; GO:0004175; GO:0005576; GO:0005615; GO:0007565; GO:0016020; GO:0008237; GO:0006508; GO:0032354; GO:0051384; GO:0008270,cell differentiation; cellular protein metabolic process; endopeptidase activity; extracellular region; extracellular space; female pregnancy; membrane; metallopeptidase activity; proteolysis; response to follicle-stimulating hormone stimulus; response to glucocorticoid stimulus; zinc ion binding,PF05572;PF00084;,,,,,,,,,PAPP1_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565] comp119588_c1_seq1,707,50.0707,1.02246674,3,23,,3.00E-32,Q13219,Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A),Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A),GO:0030154; GO:0044267; GO:0004175; GO:0005576; GO:0005615; GO:0007565; GO:0016020; GO:0008237; GO:0006508; GO:0032354; GO:0051384; GO:0008270,cell differentiation; cellular protein metabolic process; endopeptidase activity; extracellular region; extracellular space; female pregnancy; membrane; metallopeptidase activity; proteolysis; response to follicle-stimulating hormone stimulus; response to glucocorticoid stimulus; zinc ion binding,PF05572;PF00084;,,,,,,,,,PAPP1_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565] comp119601_c0_seq1,1723,41.5554,0.74472037,207,10,,8.00E-117,Q9W0Y8,Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2),Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2),GO:0042048; GO:0005886; GO:0007608; GO:0005248; GO:0001518,olfactory behavior; plasma membrane; sensory perception of smell; voltage-gated sodium channel activity; voltage-gated sodium channel complex,PF16905;PF00520;,4.00E-69,CHOYP_SCN1.2.2,,,,,,,SCN60_DROME,Drosophila melanogaster (Fruit fly),membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] comp119610_c2_seq1,509,46.3654,0.33582219,18,14,,1.00E-18,A2A9C3,Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_MOUSE,Mus musculus (Mouse),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp119623_c1_seq1,831,45.2467,0.56690313,39,35,,7.00E-66,Q9JII1,"72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV)","72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV)",GO:0032580; GO:0000139; GO:0035085; GO:0005856; GO:0046855; GO:0046856; GO:0004439,"Golgi cisterna membrane; Golgi membrane; cilium axoneme; cytoskeleton; inositol phosphate dephosphorylation; phosphatidylinositol dephosphorylation; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",PF03372;,1.00E-13,CHOYP_LOC101070553.1.1,,,,,,,INP5E_MOUSE,Mus musculus (Mouse),inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of neuron projection development [GO:0010976] comp119625_c1_seq2,684,51.9006,0.54389369,28,19,,2.00E-53,Q62985,SH2B adapter protein 1 (FceRI gamma-chain-interacting protein SH2-B) (SH2 domain-containing protein 1B) (SH2-B PH domain-containing signaling mediator 1),SH2B adapter protein 1 (FceRI gamma-chain-interacting protein SH2-B) (SH2 domain-containing protein 1B) (SH2-B PH domain-containing signaling mediator 1),GO:0005737; GO:0035556; GO:0016020; GO:0005634; GO:0005543; GO:0004871,cytoplasm; intracellular signal transduction; membrane; nucleus; phospholipid binding; signal transducer activity,PF00169;PF08916;PF00017;,6.00E-74,CHOYP_LOC552012.1.1,,,,,,,SH2B1_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of DNA biosynthetic process [GO:2000278] comp119626_c0_seq1,672,38.3929,0.32739507,408,1707,,3.00E-33,Q8R035,"Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Immature colon carcinoma transcript 1 protein homolog)","Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Immature colon carcinoma transcript 1 protein homolog)",GO:0004045; GO:0005762; GO:0070126; GO:0016150,"aminoacyl-tRNA hydrolase activity; mitochondrial large ribosomal subunit; mitochondrial translational termination; translation release factor activity, codon nonspecific",PF00472;,2.00E-23,CHOYP_AAEL_AAEL010339.1.1,3.00E-25,ruditapes2_c1697,,,,,ICT1_MOUSE,Mus musculus (Mouse),mitochondrial translational termination [GO:0070126]; rescue of stalled ribosome [GO:0072344] comp119633_c0_seq1,506,42.8854,0.38768206,15,25,,1.00E-65,P52850,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (Mndns) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)],Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (Mndns) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)],GO:0005794; GO:0000139; GO:0015016; GO:0019213; GO:0006024; GO:0015012; GO:0030210; GO:0016021; GO:0002002,Golgi apparatus; Golgi membrane; [heparan sulfate]-glucosamine N-sulfotransferase activity; deacetylase activity; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; integral to membrane; regulation of angiotensin levels in blood,PF12062;PF00685;,2.00E-28,CHOYP_NDST.1.1,,,,,,,NDST2_MOUSE,Mus musculus (Mouse),cellular process [GO:0009987]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; regulation of angiotensin levels in blood [GO:0002002] comp119634_c0_seq1,541,42.1442,0.78862124,21,59,,4.00E-42,Q5R833,"Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed]","Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed]",GO:0016787; GO:0005739,hydrolase activity; mitochondrion,PF03061;,,,,,,,,,ACO13_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp119642_c0_seq1,693,41.847,1.06769453,2181,0,,3.00E-10,Q9DAR0,Uncharacterized protein C5orf49 homolog (Y regulated sperm protein),Uncharacterized protein C5orf49 homolog (Y regulated sperm protein),,,PF15074;,,,,,,,,,CE049_MOUSE,Mus musculus (Mouse), comp119646_c1_seq1,791,44.5006,0.40930298,21,34,,2.00E-54,Q69Z66,"Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)","Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)",GO:0003677; GO:0003682; GO:0006338; GO:0042393; GO:0046872; GO:0008237; GO:0035522; GO:0005634; GO:0045944; GO:0006508; GO:0003713; GO:0006351; GO:0004221; GO:0004843,"DNA binding; chromatin binding; chromatin remodeling; histone binding; metal ion binding; metallopeptidase activity; monoubiquitinated histone H2A deubiquitination; nucleus; positive regulation of transcription from RNA polymerase II promoter; proteolysis; transcription coactivator activity; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-specific protease activity",PF01398;PF00249;PF04433;,7.00E-30,CHOYP_MYSM1.1.1,,,,,,,MYSM1_MOUSE,Mus musculus (Mouse),"chromatin remodeling [GO:0006338]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of hair follicle development [GO:0051797]; transcription, DNA-templated [GO:0006351]" comp119655_c0_seq1,419,42.9594,0.37333546,2,0,,2.00E-17,O93574,Reelin (EC 3.4.21.-) (Fragment),Reelin (EC 3.4.21.-) (Fragment),GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0005615; GO:0010001; GO:0046872; GO:0001764; GO:0018108; GO:0045860; GO:0051057; GO:0004712; GO:0005578; GO:0006508; GO:0048265; GO:0008236; GO:0021511; GO:0021517,axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; extracellular space; glial cell differentiation; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of protein kinase activity; positive regulation of small GTPase mediated signal transduction; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development,PF07974;PF12661;,,,,,,,,,RELN_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517] comp119655_c0_seq2,676,46.7456,0.35718422,28,36,,3.00E-42,O93574,Reelin (EC 3.4.21.-) (Fragment),Reelin (EC 3.4.21.-) (Fragment),GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0005615; GO:0010001; GO:0046872; GO:0001764; GO:0018108; GO:0045860; GO:0051057; GO:0004712; GO:0005578; GO:0006508; GO:0048265; GO:0008236; GO:0021511; GO:0021517,axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; extracellular space; glial cell differentiation; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of protein kinase activity; positive regulation of small GTPase mediated signal transduction; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development,PF07974;PF12661;,2.00E-17,CHOYP_RELN.3.4,,,,,,,RELN_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517] comp119664_c0_seq1,768,41.1458,0.37567235,46,59,,1.00E-77,Q5ZMV2,Spindle assembly abnormal protein 6 homolog,Spindle assembly abnormal protein 6 homolog,GO:0007049; GO:0005737; GO:0005815,cell cycle; cytoplasm; microtubule organizing center,PF16531;,1.00E-77,CHOYP_LOC100376181.1.1,,,,,,,SAS6_CHICK,Gallus gallus (Chicken),centriole replication [GO:0007099] comp119671_c0_seq1,945,51.8519,0.47906065,82,25,,1.00E-56,Q7Z7M0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872; GO:0005198,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity; structural molecule activity,PF00431;PF12947;PF07645;PF00053;PF01437;,,,,,,,,,MEGF8_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp119672_c0_seq2,248,46.371,0.52819041,4,0,,6.00E-06,Q54HW1,26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),,,PF12796;,,,,,,,,,PSD10_DICDI,Dictyostelium discoideum (Slime mold), comp119672_c1_seq1,533,44.0901,0.31037598,12,10,,3.00E-28,Q96NW4,Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein),Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein),GO:0005096; GO:0005769; GO:0045022; GO:0005085; GO:0005764; GO:0043547,GTPase activator activity; early endosome; early endosome to late endosome transport; guanyl-nucleotide exchange factor activity; lysosome; positive regulation of GTPase activity,PF12796;PF13606;PF02204;,,,,,,,,,ANR27_HUMAN,Homo sapiens (Human),"early endosome to late endosome transport [GO:0045022]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp119674_c0_seq1,1101,41.1444,0.56357246,98,960,,1.00E-115,Q9NY93,Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56),Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56),GO:0005524; GO:0004004; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent RNA helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF00271;,3.00E-131,CHOYP_LOC101168798.1.1,1.00E-14,ruditapes_c11138,,,,,DDX56_HUMAN,Homo sapiens (Human),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp119674_c0_seq3,608,41.9408,0.63734474,28,257,,6.00E-44,O60080,ATP-dependent RNA helicase dbp9 (EC 3.6.4.13),ATP-dependent RNA helicase dbp9 (EC 3.6.4.13),GO:0005524; GO:0004004; GO:0003723; GO:0005829; GO:0005730; GO:0006364,ATP binding; ATP-dependent RNA helicase activity; RNA binding; cytosol; nucleolus; rRNA processing,PF00270;PF00271;,,,,,,,,,DBP9_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp119678_c0_seq1,387,43.1525,0.33661301,11,19,,1.00E-32,Q5R5M1,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp119678_c1_seq1,491,34.8269,1.08519888,20,41,,1.00E-06,Q7TQG0,Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ),Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBTB5_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp119707_c0_seq1,411,49.3917,0.77352237,9,14,,3.00E-08,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp119719_c0_seq1,333,43.8438,0.79007218,0,53,,5.00E-25,Q8ISC9,Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48) (Fragment),Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48) (Fragment),GO:0005737; GO:0035335; GO:0004725; GO:0007362; GO:0008293,cytoplasm; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; terminal region determination; torso signaling pathway,PF00102;,,,,,,,,,CSW_DROSI,Drosophila simulans (Fruit fly),terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293] comp119723_c0_seq1,1093,43.1839,0.55166001,15,213,,2.00E-58,Q7ZWF4,RING finger protein 145,RING finger protein 145,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF13705;PF13639;,5.00E-33,CHOYP_RN145.1.1,,,,,,,RN145_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp119724_c1_seq1,591,44.5008,0.37900237,19,7,,4.00E-19,Q9TTK4,Lysosomal-trafficking regulator,Lysosomal-trafficking regulator,GO:0005737; GO:0032510; GO:0015630; GO:0042267; GO:0043473; GO:0015031,cytoplasm; endosome to lysosome transport via multivesicular body sorting pathway; microtubule cytoskeleton; natural killer cell mediated cytotoxicity; pigmentation; protein transport,PF02138;PF14844;,,,,,,,,,LYST_BOVIN,Bos taurus (Bovine),endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; lysosome organization [GO:0007040]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031] comp119738_c0_seq2,419,37.7088,0.20588353,2,8,,7.00E-07,Q6CQR3,Mitochondrial thiamine pyrophosphate carrier 1,Mitochondrial thiamine pyrophosphate carrier 1,GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,,,,,,,,,TPC1_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),thiamine pyrophosphate transport [GO:0030974] comp119738_c1_seq1,280,40.3571,0.44802867,5,52,,9.00E-06,Q54QN2,Mitochondrial substrate carrier family protein M (Solute carrier family 25 member 32 homolog),Mitochondrial substrate carrier family protein M (Solute carrier family 25 member 32 homolog),GO:0008517; GO:0016021; GO:0005743,folic acid transporter activity; integral to membrane; mitochondrial inner membrane,PF00153;,2.00E-24,CHOYP_PM34.1.1,,,,,,,MCFM_DICDI,Dictyostelium discoideum (Slime mold),translation [GO:0006412]; transport [GO:0006810] comp119738_c1_seq2,521,42.0345,0.44547015,6,41,,6.00E-45,O70579,Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17),Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17),GO:0015217; GO:0080122; GO:0005347; GO:0015230; GO:0044610; GO:0051724; GO:0015228; GO:0006635; GO:0015908; GO:0005779; GO:0005739,ADP transmembrane transporter activity; AMP transmembrane transporter activity; ATP transmembrane transporter activity; FAD transmembrane transporter activity; FMN transmembrane transporter activity; NAD transporter activity; coenzyme A transmembrane transporter activity; fatty acid beta-oxidation; fatty acid transport; integral to peroxisomal membrane; mitochondrion,PF00153;,,,,,,,,,PM34_MOUSE,Mus musculus (Mouse),ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; FAD transmembrane transport [GO:0035350]; fatty acid beta-oxidation [GO:0006635]; fatty acid transport [GO:0015908]; NAD transport [GO:0043132]; translation [GO:0006412] comp119751_c0_seq1,571,36.7776,0.46732169,16,123,,3.00E-08,Q5UR03,Uncharacterized protein L905,Uncharacterized protein L905,GO:0016706,"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13532;,,,,,,,,,YL905_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp119751_c1_seq1,258,41.0853,0.28682601,9,6,,2.00E-32,Q2M2S8,"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7)","Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7)",GO:0051213; GO:0006631; GO:0046872; GO:0005759; GO:0070265; GO:0010883; GO:0006974,dioxygenase activity; fatty acid metabolic process; metal ion binding; mitochondrial matrix; necrotic cell death; regulation of lipid storage; response to DNA damage stimulus,PF13532;,,,,,,,,,ALKB7_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; fatty acid metabolic process [GO:0006631]; regulation of lipid storage [GO:0010883]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445] comp119754_c0_seq1,1028,46.1089,0.42917803,54,41,,9.00E-118,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,6.00E-140,CHOYP_EMAL6.1.1,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp119754_c1_seq1,225,46.6667,0.33482143,5,0,,2.00E-25,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,,,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp119756_c0_seq1,445,40,0.44856548,8,71,,5.00E-15,Q8IYD8,Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0071821; GO:0043240; GO:0003682; GO:0004518; GO:0090305; GO:0031297; GO:0000712,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; FANCM-MHF complex; Fanconi anaemia nuclear complex; chromatin binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; replication fork processing; resolution of meiotic recombination intermediates,PF02732;PF16783;PF00271;PF04851;,,,,,,,,,FANCM_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp119775_c0_seq1,559,39.5349,0.50683065,22,49,,2.00E-12,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp119780_c0_seq1,903,40.1993,0.37178154,18,274,,1.00E-105,O15305,Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8),Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8),GO:0009298; GO:0005829; GO:0006488; GO:0019307; GO:0043025; GO:0004615; GO:0043687; GO:0018279,GDP-mannose biosynthetic process; cytosol; dolichol-linked oligosaccharide biosynthetic process; mannose biosynthetic process; neuronal cell body; phosphomannomutase activity; post-translational protein modification; protein N-linked glycosylation via asparagine,PF03332;,1.00E-84,CHOYP_BRAFLDRAFT_113552.1.1,5.00E-36,ruditapes_c22901,,,,,PMM2_HUMAN,Homo sapiens (Human),GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486] comp119800_c0_seq1,537,44.3203,0.23328837,0,0,,,,,,,,,5.00E-42,CHOYP_PHYD1.2.2,,,,,,,,, comp119800_c0_seq2,1223,39.4113,0.33867727,8,90,,7.00E-78,Q5U3U0,Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-),Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-),GO:0051213; GO:0046872,dioxygenase activity; metal ion binding,PF05721;,,,,,,,,,PHYD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp119803_c0_seq1,995,41.9095,0.52710592,997,2830,,3.00E-95,Q6AZN4,"39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15)","39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15)",GO:0015934; GO:0005739; GO:0003735; GO:0006412,large ribosomal subunit; mitochondrion; structural constituent of ribosome; translation,PF00828;,,,1.00E-57,ruditapes_c6968,,,,,RM15_XENLA,Xenopus laevis (African clawed frog),translation [GO:0006412] comp119821_c0_seq1,442,46.6063,0.34458125,9,10,,3.00E-52,P51648,Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 10) (Aldehyde dehydrogenase family 3 member A2) (Microsomal aldehyde dehydrogenase),Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 10) (Aldehyde dehydrogenase family 3 member A2) (Microsomal aldehyde dehydrogenase),GO:0004029; GO:0004030; GO:0006081; GO:0007417; GO:0005789; GO:0008544; GO:0016021; GO:0043231; GO:0046577; GO:0050061; GO:0052814; GO:0005743; GO:0007422; GO:0005777; GO:0033306; GO:0006714,aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; cellular aldehyde metabolic process; central nervous system development; endoplasmic reticulum membrane; epidermis development; integral to membrane; intracellular membrane-bounded organelle; long-chain-alcohol oxidase activity; long-chain-aldehyde dehydrogenase activity; medium-chain-aldehyde dehydrogenase activity; mitochondrial inner membrane; peripheral nervous system development; peroxisome; phytol metabolic process; sesquiterpenoid metabolic process,PF00171;,,,,,,,,,AL3A2_HUMAN,Homo sapiens (Human),cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; formaldehyde metabolic process [GO:0046292]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; response to reactive oxygen species [GO:0000302]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148] comp119821_c0_seq2,339,45.4277,0.35583774,0,0,,1.00E-07,P25553,Lactaldehyde dehydrogenase (EC 1.2.1.22) (Aldehyde dehydrogenase A) (Glycolaldehyde dehydrogenase) (EC 1.2.1.21),Lactaldehyde dehydrogenase (EC 1.2.1.22) (Aldehyde dehydrogenase A) (Glycolaldehyde dehydrogenase) (EC 1.2.1.21),GO:0019571; GO:0042355; GO:0050569; GO:0008911; GO:0019301; GO:0004777,D-arabinose catabolic process; L-fucose catabolic process; glycolaldehyde dehydrogenase activity; lactaldehyde dehydrogenase activity; rhamnose catabolic process; succinate-semialdehyde dehydrogenase (NAD+) activity,PF00171;,,,,,,,,,ALDA_ECOLI,Escherichia coli (strain K12),L-fucose catabolic process [GO:0042355]; rhamnose catabolic process [GO:0019301] comp119825_c0_seq1,1802,40.788,0.57193154,52,479,,9.00E-132,P38942,4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-),4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-),GO:0006084; GO:0016740,acetyl-CoA metabolic process; transferase activity,PF13336;PF02550;,5.00E-131,CHOYP_ISCW_ISCW023591.1.1,,,,,,,CAT2_CLOK5,Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680),acetyl-CoA metabolic process [GO:0006084] comp119827_c0_seq1,741,44.5344,0.32706495,17,83,,6.00E-28,Q9H0Y0,Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-) (Autophagy-related protein 10) (APG10-like),Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-) (Autophagy-related protein 10) (APG10-like),GO:0019777; GO:0034263; GO:0005737; GO:0005622; GO:0031401; GO:0006497; GO:0032446; GO:0015031,Atg12 ligase activity; autophagy in response to ER overload; cytoplasm; intracellular; positive regulation of protein modification process; protein lipidation; protein modification by small protein conjugation; protein transport,PF03987;,,,,,,,,,ATG10_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; autophagy in response to ER overload [GO:0034263]; macroautophagy [GO:0016236]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031] comp119843_c0_seq1,649,39.1371,0.92696153,12,48,,2.00E-29,A6QQW0,Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN143_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp119843_c0_seq2,327,37.3089,0.97911363,0,7,,5.00E-10,Q8K083,Zinc finger protein 536,Zinc finger protein 536,GO:0046872; GO:0045665; GO:0048387; GO:0005634; GO:0006355; GO:0044323; GO:0006351,"metal ion binding; negative regulation of neuron differentiation; negative regulation of retinoic acid receptor signaling pathway; nucleus; regulation of transcription, DNA-dependent; retinoic acid-responsive element binding; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN536_MOUSE,Mus musculus (Mouse),negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription from RNA polymerase II promoter [GO:0006366] comp119847_c1_seq1,474,44.5148,0.7044896,8,91,,3.00E-67,Q9JK84,Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A),Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A),GO:0007049; GO:0051301; GO:0005737; GO:0005886; GO:0005923,cell cycle; cell division; cytoplasm; plasma membrane; tight junction,PF00564;PF00595;,6.00E-91,CHOYP_LOC587966.1.1,,,,,,,PAR6G_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell division [GO:0051301] comp119848_c2_seq1,485,43.9175,0.47218007,0,8,,8.00E-43,Q8BHT6,"Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta-3-glycosyltransferase-like)","Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like)",GO:0005789; GO:0006004; GO:0016021; GO:0006486; GO:0016757,"endoplasmic reticulum membrane; fucose metabolic process; integral to membrane; protein glycosylation; transferase activity, transferring glycosyl groups",PF02434;,,,,,,,,,B3GLT_MOUSE,Mus musculus (Mouse),fucose metabolic process [GO:0006004]; protein glycosylation [GO:0006486] comp119852_c0_seq1,546,47.619,0.61863303,1,102,,1.00E-62,Q5FWS6,Kazrin,Kazrin,GO:0001533; GO:0005737; GO:0030057; GO:0031424; GO:0005634,cornified envelope; cytoplasm; desmosome; keratinization; nucleus,PF00536;PF07647;,,,,,,,,,KAZRN_RAT,Rattus norvegicus (Rat),keratinization [GO:0031424] comp119855_c0_seq2,756,50.7937,0.53390935,16,55,,2.00E-48,P55196,Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),GO:0034332; GO:0045177; GO:0007155; GO:0034329; GO:0005913; GO:0005911; GO:0007267; GO:0005829; GO:0005634; GO:0005886; GO:0008022; GO:0007165,adherens junction organization; apical part of cell; cell adhesion; cell junction assembly; cell-cell adherens junction; cell-cell junction; cell-cell signaling; cytosol; nucleus; plasma membrane; protein C-terminus binding; signal transduction,PF01843;PF00498;PF00595;PF00788;,3.00E-15,CHOYP_BRAFLDRAFT_208117.3.3,,,,,,,AFAD_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp119856_c0_seq1,501,42.9142,0.86677917,24,120,,3.00E-49,Q10S72,4-coumarate--CoA ligase-like 4 (EC 6.2.1.-),4-coumarate--CoA ligase-like 4 (EC 6.2.1.-),GO:0005524; GO:0016874,ATP binding; ligase activity,PF00501;PF13193;,,,,,,,,,4CLL4_ORYSJ,Oryza sativa subsp. japonica (Rice),metabolic process [GO:0008152] comp119864_c0_seq1,587,34.9233,0.7424264,19,58,,7.00E-06,Q99315,Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)],Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,,,,,,,,,YG31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp119878_c0_seq1,1025,30.8293,0.82228089,2995,141,,8.00E-14,Q9UTI2,Glutaredoxin-2,Glutaredoxin-2,GO:0045454; GO:0009055; GO:0004602; GO:0004364; GO:0005739; GO:0015035; GO:0019430,cell redox homeostasis; electron carrier activity; glutathione peroxidase activity; glutathione transferase activity; mitochondrion; protein disulfide oxidoreductase activity; removal of superoxide radicals,PF00462;,,,1.00E-88,ruditapes2_c1811,,,,,GLRX2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430] comp119883_c0_seq1,406,43.1034,0.61211747,5,84,,2.00E-13,P02707,Hepatic lectin,Hepatic lectin,GO:0030246; GO:0006897; GO:0016021,carbohydrate binding; endocytosis; integral to membrane,PF00059;,,,,,,,,,LECH_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp119887_c0_seq1,744,38.8441,0.14565031,17,164,,2.00E-48,Q3LIE5,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase),Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase),GO:0047631; GO:0047734; GO:0046872,ADP-ribose diphosphatase activity; CDP-glycerol diphosphatase activity; metal ion binding,PF00149;,,,,,,,,,ADPRM_HUMAN,Homo sapiens (Human),nucleobase-containing small molecule catabolic process [GO:0034656] comp119898_c0_seq1,1403,45.9729,1.10834336,0,0,,4.00E-12,Q2T9W3,Coiled-coil domain-containing protein 63,Coiled-coil domain-containing protein 63,,,,,,,,,,,,CCD63_BOVIN,Bos taurus (Bovine),spermatid development [GO:0007286] comp119898_c0_seq2,971,38.9289,1.04347937,65,8,,2.00E-07,P63014,Paired mesoderm homeobox protein 1 (Paired-related homeobox protein 1) (PRX-1) (rHox),Paired mesoderm homeobox protein 1 (Paired-related homeobox protein 1) (PRX-1) (rHox),GO:0048844; GO:0051216; GO:0048701; GO:0030326; GO:0042472; GO:0042474; GO:0000122; GO:0005634; GO:0060021; GO:0002053; GO:0045880; GO:0043565; GO:0003700,artery morphogenesis; cartilage development; embryonic cranial skeleton morphogenesis; embryonic limb morphogenesis; inner ear morphogenesis; middle ear morphogenesis; negative regulation of transcription from RNA polymerase II promoter; nucleus; palate development; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;PF03826;,,,,,,,,,PRRX1_RAT,Rattus norvegicus (Rat),artery morphogenesis [GO:0048844]; cartilage development [GO:0051216]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; inner ear morphogenesis [GO:0042472]; middle ear morphogenesis [GO:0042474]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; neuron fate determination [GO:0048664]; palate development [GO:0060021]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of neuron projection regeneration [GO:0070570] comp119898_c0_seq3,2423,41.6839,0.99910845,95,0,,2.00E-57,Q2T9W3,Coiled-coil domain-containing protein 63,Coiled-coil domain-containing protein 63,,,,,,,,,,,,CCD63_BOVIN,Bos taurus (Bovine),spermatid development [GO:0007286] comp119898_c0_seq4,1991,37.3179,0.86919865,0,0,,,,,,,,,3.00E-27,CHOYP_BRAFLDRAFT_126033.1.1,,,,,,,,, comp119901_c1_seq1,1071,43.1373,0.38825066,28,45,,5.00E-29,Q92543,Sorting nexin-19,Sorting nexin-19,GO:0007154; GO:0030659; GO:0035091; GO:0015031,cell communication; cytoplasmic vesicle membrane; phosphatidylinositol binding; protein transport,PF08628;PF00787;PF02194;,,,,,,,,,SNX19_HUMAN,Homo sapiens (Human),chondrocyte differentiation [GO:0002062]; dense core granule maturation [GO:1990502]; exocytosis [GO:0006887]; insulin secretion [GO:0030073] comp119901_c1_seq2,427,42.3888,0.42492167,0,0,,,,,,,,,1.00E-16,CHOYP_SNX19.1.1,,,,,,,,, comp119902_c1_seq1,682,47.0674,0.50683596,34,28,,4.00E-109,Q8IV36,Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog),Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog),GO:0005797; GO:0000138; GO:0005881; GO:0090498; GO:0006886; GO:0005886; GO:0031001,Golgi medial cisterna; Golgi trans cisterna; cytoplasmic microtubule; extrinsic to Golgi membrane; intracellular protein transport; plasma membrane; response to brefeldin A,,9.00E-142,CHOYP_LOC100374703.1.1,,,,,,,HID1_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; response to brefeldin A [GO:0031001] comp119903_c0_seq1,402,41.791,0.49056907,17,22,,2.00E-34,Q8BMP6,Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7),Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7),GO:0000139; GO:0000062; GO:0016021; GO:0005739; GO:0006694; GO:0006810,Golgi membrane; fatty-acyl-CoA binding; integral to membrane; mitochondrion; steroid biosynthetic process; transport,PF00887;PF13897;,1.00E-30,CHOYP_BRAFLDRAFT_278625.1.2,1.00E-45,ruditapes2_c1736,,,,,GCP60_MOUSE,Mus musculus (Mouse),steroid biosynthetic process [GO:0006694]; transport [GO:0006810] comp119908_c1_seq1,958,36.6388,0.34296806,35,100,,2.00E-41,Q5F362,Cell cycle control protein 50A (Transmembrane protein 30A),Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A),GO:0016021,integral to membrane,PF03381;,,,,,,,,,CC50A_CHICK,Gallus gallus (Chicken),phospholipid transport [GO:0015914] comp119914_c0_seq2,972,40.3292,0.22880982,0,0,,4.00E-11,Q12251,Uncharacterized mitochondrial carrier YPR011C,Uncharacterized mitochondrial carrier YPR011C,GO:0016021; GO:0005743; GO:0055085; GO:0005215,integral to membrane; mitochondrial inner membrane; transmembrane transport; transporter activity,PF00153;,,,,,,,,,YP011_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),3'-phospho-5'-adenylyl sulfate transmembrane transport [GO:1902559]; 5'-adenylyl sulfate transmembrane transport [GO:1902558]; translation [GO:0006412] comp119914_c0_seq3,1122,41.0873,0.29827381,10,17,,4.00E-91,Q6P316,Solute carrier family 25 member 40,Solute carrier family 25 member 40,GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,,,,,,,,,S2540_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),translation [GO:0006412]; transmembrane transport [GO:0055085] comp119920_c0_seq2,555,43.4234,0.66190691,2,0,,7.00E-69,Q62910,"Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)","Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)",GO:0003723; GO:0017124; GO:0007420; GO:0005737; GO:0006897; GO:0043005; GO:0000166; GO:0046856; GO:0034595; GO:0004439; GO:0014015; GO:0048260; GO:0043234; GO:0032403; GO:0034097; GO:0032526,"RNA binding; SH3 domain binding; brain development; cytoplasm; endocytosis; neuron projection; nucleotide binding; phosphatidylinositol dephosphorylation; phosphatidylinositol phosphate 5-phosphatase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; positive regulation of gliogenesis; positive regulation of receptor-mediated endocytosis; protein complex; protein complex binding; response to cytokine stimulus; response to retinoic acid",PF08952;PF03372;PF02383;,9.00E-33,CHOYP_SYNJ1.1.1,,,,,,,SYNJ1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488] comp119925_c1_seq1,673,38.4844,0.32750315,33,131,,1.00E-35,Q5U3N7,Protein Churchill,Protein Churchill,GO:0042074; GO:0090243; GO:0030336; GO:0040037; GO:0045893; GO:0042661; GO:0006351; GO:0008270,"cell migration involved in gastrulation; fibroblast growth factor receptor signaling pathway involved in somitogenesis; negative regulation of cell migration; negative regulation of fibroblast growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of mesodermal cell fate specification; transcription, DNA-dependent; zinc ion binding",PF06573;,,,3.00E-50,ruditapes_c12859,,,,,CHUR_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell migration involved in gastrulation [GO:0042074]; fibroblast growth factor receptor signaling pathway involved in somitogenesis [GO:0090243]; negative regulation of cell migration [GO:0030336]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell migration [GO:0030334]; regulation of mesodermal cell fate specification [GO:0042661]; transcription, DNA-templated [GO:0006351]" comp119926_c0_seq1,1086,40.884,0.57387151,64,10,,3.00E-34,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,,,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp119932_c0_seq1,299,38.4615,0.72596093,2,0,,2.00E-08,Q9MZD1,Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),GO:0016021; GO:0005765; GO:0015293,integral to membrane; lysosomal membrane; symporter activity,PF07690;,,,,,,,,,S17A5_SHEEP,Ovis aries (Sheep), comp119932_c0_seq2,374,41.1765,0.65411247,0,9,,1.00E-12,Q9MZD1,Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),GO:0016021; GO:0005765; GO:0015293,integral to membrane; lysosomal membrane; symporter activity,PF07690;,5.00E-59,CHOYP_PHUM_PHUM504500.1.1,,,,,,,S17A5_SHEEP,Ovis aries (Sheep), comp119934_c0_seq1,411,47.6886,0.6435527,7,44,,2.00E-16,Q9ERE8,Mesoderm development candidate 1,Mesoderm development candidate 1,,,,,,,,,,,,MESD1_MOUSE,Mus musculus (Mouse), comp119936_c0_seq1,399,50.1253,0.9312742,5,43,,2.00E-25,H2A0M7,Peroxidase-like protein,Peroxidase-like protein,GO:0005576; GO:0020037; GO:0004601; GO:0006979,extracellular region; heme binding; peroxidase activity; response to oxidative stress,PF03098;,,,,,,,,,PLSP_PINMG,Pinctada margaritifera (Black-lipped pearl oyster),response to oxidative stress [GO:0006979] comp119936_c1_seq1,523,42.4474,0.72677103,3,107,,8.00E-18,B3A0Q8,Peroxidase-like protein 3 (Fragment),Peroxidase-like protein 3 (Fragment),GO:0005576; GO:0020037; GO:0004601; GO:0006979,extracellular region; heme binding; peroxidase activity; response to oxidative stress,PF03098;,,,,,,,,,PLSP2_LOTGI,Lottia gigantea (Giant owl limpet),response to oxidative stress [GO:0006979] comp119941_c0_seq1,540,39.8148,0.66299247,6,20,,5.00E-11,Q9JMB8,Contactin-6 (Neural recognition molecule NB-3) (mNB-3),Contactin-6 (Neural recognition molecule NB-3) (mNB-3),GO:0007219; GO:0031225; GO:0007155; GO:0005886,Notch signaling pathway; anchored to membrane; cell adhesion; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN6_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219] comp119943_c0_seq1,922,42.0824,0.67334115,17,64,,5.00E-56,P95896,Amidase (EC 3.5.1.4),Amidase (EC 3.5.1.4),GO:0004040; GO:0016884,"amidase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor",PF01425;,,,,,,,,,AMID_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2), comp119959_c0_seq2,496,41.3306,0.20389826,14,41,,4.00E-25,Q641C8,S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26),S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26),GO:0000095; GO:0016021; GO:0005743,S-adenosyl-L-methionine transmembrane transporter activity; integral to membrane; mitochondrial inner membrane,PF00153;,,,,,,,,,SAMC_XENLA,Xenopus laevis (African clawed frog),S-adenosyl-L-methionine transport [GO:0015805] comp119960_c0_seq1,236,36.4407,0.77961926,12,16,,9.00E-13,P09523,Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF02160;PF00078;,,,,,,,,,POL_FMVD,Figwort mosaic virus (strain DxS) (FMV), comp119965_c0_seq1,739,39.1069,0.62686979,30,71,,2.00E-30,O95786,Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),GO:0005524; GO:0008026; GO:0039529; GO:0015629; GO:0005829; GO:0009597; GO:0003690; GO:0003725; GO:0045087; GO:0019048; GO:0032480; GO:0002230; GO:0032727; GO:0032728; GO:0051091; GO:0042993; GO:0045944; GO:0030334; GO:0034344; GO:0043330; GO:0032587; GO:0003727; GO:0005923; GO:0008270,ATP binding; ATP-dependent helicase activity; RIG-I signaling pathway; actin cytoskeleton; cytosol; detection of virus; double-stranded DNA binding; double-stranded RNA binding; innate immune response; modulation by virus of host morphology or physiology; negative regulation of type I interferon production; positive regulation of defense response to virus by host; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of cell migration; regulation of type III interferon production; response to exogenous dsRNA; ruffle membrane; single-stranded RNA binding; tight junction; zinc ion binding,PF16739;PF00270;PF00271;PF11648;,,,,,,,,,DDX58_HUMAN,Homo sapiens (Human),cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032] comp119965_c2_seq2,1117,40.8236,0.39262542,21,22,,9.00E-30,Q6Q899,Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),GO:0005524; GO:0008026; GO:0039529; GO:0015629; GO:0005829; GO:0009597; GO:0003690; GO:0003725; GO:0045087; GO:0002230; GO:0032727; GO:0032728; GO:0042993; GO:0045944; GO:0030334; GO:0043330; GO:0009615; GO:0032587; GO:0003727; GO:0005923; GO:0008270,ATP binding; ATP-dependent helicase activity; RIG-I signaling pathway; actin cytoskeleton; cytosol; detection of virus; double-stranded DNA binding; double-stranded RNA binding; innate immune response; positive regulation of defense response to virus by host; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of cell migration; response to exogenous dsRNA; response to virus; ruffle membrane; single-stranded RNA binding; tight junction; zinc ion binding,PF16739;PF00271;PF04851;PF11648;,,,,,,,,,DDX58_MOUSE,Mus musculus (Mouse),detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529] comp119970_c1_seq2,1005,34.9254,0.32779439,22,69,,2.00E-27,Q9JJK3,Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3),Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3),GO:0005779; GO:0045046,integral to peroxisomal membrane; protein import into peroxisome membrane,PF04882;,,,,,,,,,PEX3_CRILO,Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster),peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046] comp119978_c2_seq1,297,44.1077,0.41972307,10,47,,4.00E-25,F1MF21,PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP),PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP),GO:0003677; GO:0006281; GO:0000785; GO:0005737; GO:2000042; GO:0005634,DNA binding; DNA repair; chromatin; cytoplasm; negative regulation of double-strand break repair via homologous recombination; nucleus,,,,,,,,,,PARI_BOVIN,Bos taurus (Bovine),DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042] comp119981_c0_seq2,1081,46.716,0.52835405,34,30,,4.00E-42,Q2KHR2,DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2),DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2),GO:0003677; GO:0005634; GO:0006355,"DNA binding; nucleus; regulation of transcription, DNA-dependent",PF02257;,,,,,,,,,RFX7_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp119983_c0_seq1,463,33.4773,0.92800433,326,1147,,,,,,,,,,,6.00E-19,ruditapes_lrc30921,,,,,,, comp119983_c1_seq1,525,45.9048,0.58250488,162,952,,7.00E-100,Q92005,Elongation factor 1-alpha (EF-1-alpha),Elongation factor 1-alpha (EF-1-alpha),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,4.00E-88,CHOYP_EF1A.4.4,8.00E-120,ruditapes2_c1,,,,,EF1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp119983_c2_seq1,485,42.6804,0.41047472,43,351,,6.00E-96,Q26487,Elongation factor 1-alpha (EF-1-alpha) (Fragment),Elongation factor 1-alpha (EF-1-alpha) (Fragment),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,4.00E-81,CHOYP_EF1A.3.4,1.00E-47,ruditapes_lrc15460,,,,,EF1A_SPOFR,Spodoptera frugiperda (Fall armyworm), comp119994_c1_seq2,365,41.0959,0.39746905,15,22,,4.00E-10,Q9EQ25,Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3),Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3),GO:0015171; GO:0016021; GO:0005886; GO:0006814; GO:0015293,amino acid transmembrane transporter activity; integral to membrane; plasma membrane; sodium ion transport; symporter activity,PF01490;,,,,,,,,,S38A4_RAT,Rattus norvegicus (Rat),sodium ion transport [GO:0006814] comp119994_c1_seq4,695,44.1727,0.53238254,7,16,,8.00E-52,Q9HBR0,Putative sodium-coupled neutral amino acid transporter 10 (Solute carrier family 38 member 10),Putative sodium-coupled neutral amino acid transporter 10 (Solute carrier family 38 member 10),GO:0006865; GO:0060348; GO:0016021; GO:0006814,amino acid transport; bone development; integral to membrane; sodium ion transport,PF01490;,4.00E-51,CHOYP_BRAFLDRAFT_90902.2.2,,,,,,,S38AA_HUMAN,Homo sapiens (Human),amino acid transmembrane transport [GO:0003333]; bone development [GO:0060348]; sodium ion transport [GO:0006814] comp120009_c1_seq1,1137,44.0633,0.57182266,6,14,,5.00E-85,Q5VV63,Attractin-like protein 1,Attractin-like protein 1,GO:0007186; GO:0030246; GO:0016021; GO:0007275; GO:0004872,G-protein coupled receptor signaling pathway; carbohydrate binding; integral to membrane; multicellular organismal development; receptor activity,PF00431;PF07974;PF01344;PF00059;PF01437;,,,,,,,,,ATRN1_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186] comp120009_c1_seq2,1086,44.0147,0.58491225,0,0,,5.00E-13,Q8BYI9,Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin),Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin),GO:0008306; GO:0009986; GO:0005737; GO:0030198; GO:0035641; GO:0060291; GO:0045121; GO:0048692; GO:0022408; GO:0050805; GO:0050885; GO:0007158; GO:0005634; GO:0072534; GO:0051968; GO:0005578; GO:0046625; GO:0050808; GO:0022029,"associative learning; cell surface; cytoplasm; extracellular matrix organization; locomotory exploration behavior; long-term synaptic potentiation; membrane raft; negative regulation of axon extension involved in regeneration; negative regulation of cell-cell adhesion; negative regulation of synaptic transmission; neuromuscular process controlling balance; neuron cell-cell adhesion; nucleus; perineuronal net; positive regulation of synaptic transmission, glutamatergic; proteinaceous extracellular matrix; sphingolipid binding; synapse organization; telencephalon cell migration",PF00147;PF00041;,,,,,,,,,TENR_MOUSE,Mus musculus (Mouse),"associative learning [GO:0008306]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; synapse organization [GO:0050808]; telencephalon cell migration [GO:0022029]" comp120011_c1_seq1,839,43.8617,0.64602097,12,88,,2.00E-17,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp120012_c0_seq1,827,46.9166,0.52890528,22,80,,2.00E-38,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,2.00E-74,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp120014_c0_seq1,913,50.8215,0.64049319,43,40,,5.00E-35,Q7KW14,Coiled-coil domain-containing protein CG32809,Coiled-coil domain-containing protein CG32809,,,PF03915;,4.00E-15,CHOYP_LOC100883165.2.2,,,,,,,CCDCX_DROME,Drosophila melanogaster (Fruit fly), comp120021_c0_seq1,255,33.3333,0.71669635,0,0,,,,,,,,,,,5.00E-11,ruditapes_c18710,,,,,,, comp120022_c0_seq1,752,50,0.53650916,35,26,,,,,,,,,4.00E-26,CHOYP_LOC662211.1.1,,,,,,,,, comp120025_c0_seq2,945,31.2169,0.35404231,15,77,,9.00E-28,Q8N6N2,Tetratricopeptide repeat protein 9B (TPR repeat protein 9B),Tetratricopeptide repeat protein 9B (TPR repeat protein 9B),,,PF07719;,,,,,,,,,TTC9B_HUMAN,Homo sapiens (Human),chaperone-mediated protein folding [GO:0061077] comp120031_c0_seq1,1057,32.4503,0.08255957,30,54,,,,,,,,,,,8.00E-16,ruditapes_c27963,,,,,,, comp120031_c1_seq1,1494,32.4632,0.13584987,46,58,,,,,,,,,,,7.00E-37,ruditapes_c10022,,,,,,, comp120044_c0_seq3,1101,34.9682,0.30785588,6,0,,9.00E-06,Q8BG95,Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2),Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2),GO:0005737,cytoplasm,PF12796;PF15898;,,,,,,,,,MYPT2_MOUSE,Mus musculus (Mouse),signal transduction [GO:0007165] comp120044_c0_seq4,1002,34.9301,0.3063222,2,12,,7.00E-37,Q61858,G patch domain and ankyrin repeat-containing protein 1 (G5 protein) (HLA-B-associated transcript 4),G patch domain and ankyrin repeat-containing protein 1 (G5 protein) (HLA-B-associated transcript 4),GO:0003676,nucleic acid binding,PF01585;,5.00E-20,CHOYP_BRAFLDRAFT_64382.1.2,,,,,,,GPAN1_MOUSE,Mus musculus (Mouse), comp120047_c0_seq1,274,41.9708,0.50769907,4,29,,3.00E-12,P30771,ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1),ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1),GO:0005524; GO:0004004; GO:0003677; GO:0030466; GO:0005737; GO:0008298; GO:0070478; GO:0003676; GO:0005634; GO:0005844; GO:0016567; GO:0006449; GO:0043024; GO:0008270,"ATP binding; ATP-dependent RNA helicase activity; DNA binding; chromatin silencing at silent mating-type cassette; cytoplasm; intracellular mRNA localization; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; nucleic acid binding; nucleus; polysome; protein ubiquitination; regulation of translational termination; ribosomal small subunit binding; zinc ion binding",PF09416;,,,,,,,,,NAM7_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"chromatin silencing at silent mating-type cassette [GO:0030466]; DNA recombination [GO:0006310]; intracellular mRNA localization [GO:0008298]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein ubiquitination [GO:0016567]; regulation of translational termination [GO:0006449]" comp120047_c2_seq1,863,41.3673,0.51864091,27,45,,1.00E-35,Q9BYK8,"Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)","Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)",GO:0005524; GO:0003677; GO:0044255; GO:0004386; GO:0030374; GO:0046872; GO:0005654; GO:0045944; GO:0044281; GO:0006351,"ATP binding; DNA binding; cellular lipid metabolic process; helicase activity; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; transcription, DNA-dependent",,,,,,,,,,PR285_HUMAN,Homo sapiens (Human),"cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp120049_c0_seq1,793,40.1009,0.40991289,29,35,,2.00E-08,A0KGY8,UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.87) (UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase) (UDP-Ara4O aminotransferase) (UDP-4-amino-4-deoxy-L-arabinose aminotransferase),UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.87) (UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase) (UDP-Ara4O aminotransferase) (UDP-4-amino-4-deoxy-L-arabinose aminotransferase),GO:0009245; GO:0009103; GO:0030170; GO:0046677; GO:0008483,lipid A biosynthetic process; lipopolysaccharide biosynthetic process; pyridoxal phosphate binding; response to antibiotic; transaminase activity,PF01041;,6.00E-24,CHOYP_LOC100367139.1.1,,,,,,,ARNB_AERHH,Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240),lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; response to antibiotic [GO:0046677] comp120057_c0_seq1,416,45.1923,0.66341292,15,48,,3.00E-13,Q96S96,Phosphatidylethanolamine-binding protein 4 (PEBP-4) (hPEBP4) (Protein cousin-of-RKIP 1),Phosphatidylethanolamine-binding protein 4 (PEBP-4) (hPEBP4) (Protein cousin-of-RKIP 1),GO:0005764,lysosome,PF01161;,,,,,,,,,PEBP4_HUMAN,Homo sapiens (Human), comp120062_c1_seq1,348,45.1149,0.33993787,15,9,,1.00E-26,Q96AG3,Solute carrier family 25 member 46,Solute carrier family 25 member 46,GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,,,,,,,,,S2546_HUMAN,Homo sapiens (Human),mitochondrial membrane fission [GO:0090149]; transport [GO:0006810] comp120065_c1_seq1,322,41.6149,0.43327044,7,25,,7.00E-17,Q99685,Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL),Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL),GO:0036155; GO:0047372; GO:0019369; GO:0004091; GO:0005789; GO:0006633; GO:0046474; GO:0006954; GO:0008289; GO:0060292; GO:0004622; GO:0005886; GO:0030168; GO:2000124; GO:0050727; GO:0051930; GO:0045202; GO:0019433,acylglycerol acyl-chain remodeling; acylglycerol lipase activity; arachidonic acid metabolic process; carboxylesterase activity; endoplasmic reticulum membrane; fatty acid biosynthetic process; glycerophospholipid biosynthetic process; inflammatory response; lipid binding; long term synaptic depression; lysophospholipase activity; plasma membrane; platelet activation; regulation of endocannabinoid signaling pathway; regulation of inflammatory response; regulation of sensory perception of pain; synapse; triglyceride catabolic process,PF12146;,,,,,,,,,MGLL_HUMAN,Homo sapiens (Human),acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433] comp120072_c0_seq1,1450,43.7241,0.50935283,6,7,,2.00E-116,Q6DH69,Fatty-acid amide hydrolase 2-A (EC 3.5.1.99),Fatty-acid amide hydrolase 2-A (EC 3.5.1.99),GO:0016884; GO:0016787; GO:0016021,"carbon-nitrogen ligase activity, with glutamine as amido-N-donor; hydrolase activity; integral to membrane",PF01425;,,,,,,,,,FAH2A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp120072_c0_seq2,1368,43.9327,0.53947427,0,0,,2.00E-99,Q6DH69,Fatty-acid amide hydrolase 2-A (EC 3.5.1.99),Fatty-acid amide hydrolase 2-A (EC 3.5.1.99),GO:0016884; GO:0016787; GO:0016021,"carbon-nitrogen ligase activity, with glutamine as amido-N-donor; hydrolase activity; integral to membrane",PF01425;,6.00E-27,CHOYP_FAH2A.1.1,,,,,,,FAH2A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp120075_c0_seq1,461,49.4577,0.71148406,12,0,,4.00E-11,Q3ZAV0,Coiled-coil domain-containing protein 60,Coiled-coil domain-containing protein 60,,,PF15769;,,,,,,,,,CCD60_RAT,Rattus norvegicus (Rat), comp120082_c0_seq2,436,45.6422,0.62492668,1,15,,2.00E-27,Q8K274,Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein),Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein),GO:0016301,kinase activity,PF03881;,,,,,,,,,KT3K_MOUSE,Mus musculus (Mouse), comp120086_c0_seq1,690,36.087,0.71662064,10,28,,3.00E-121,Q9CPY6,Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog),Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog),,,PF09783;,5.00E-145,CHOYP_LOC100642891.1.1,,,2.00E-140,CU992983.p.cg.6,8,,GID4_MOUSE,Mus musculus (Mouse), comp120095_c1_seq1,916,42.5764,0.38114152,45,24,,2.00E-18,P51123,Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (TAFII250) (TBP-associated factor 230 kDa) (p230) (Transcription initiation factor TFIID 230 kDa subunit) (TAFII-230),Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (TAFII250) (TBP-associated factor 230 kDa) (p230) (Transcription initiation factor TFIID 230 kDa subunit) (TAFII-230),GO:0005524; GO:0001129; GO:0016573; GO:0035174; GO:0022008; GO:0045944; GO:0060261; GO:0046425; GO:0000117; GO:0043565; GO:0005669; GO:0008270,ATP binding; TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly; histone acetylation; histone serine kinase activity; neurogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription initiation from RNA polymerase II promoter; regulation of JAK-STAT cascade; regulation of transcription involved in G2/M transition of mitotic cell cycle; sequence-specific DNA binding; transcription factor TFIID complex; zinc ion binding,PF00439;PF12157;PF09247;,2.00E-18,CHOYP_TAF1.1.1,4.00E-38,ruditapes_c14896,,,,,TAF1_DROME,Drosophila melanogaster (Fruit fly),"cell cycle [GO:0007049]; DNA-templated transcription, initiation [GO:0006352]; histone H3-K14 acetylation [GO:0044154]; histone H4 acetylation [GO:0043967]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein complex assembly [GO:0006461]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp120095_c2_seq1,256,45.7031,0.30058938,7,10,,2.00E-17,Q8TEQ6,Gem-associated protein 5 (Gemin5),Gem-associated protein 5 (Gemin5),GO:0097504; GO:0005829; GO:0034660; GO:0016604; GO:0006461; GO:0017069; GO:0005681; GO:0000387,Gemini of coiled bodies; cytosol; ncRNA metabolic process; nuclear body; protein complex assembly; snRNA binding; spliceosomal complex; spliceosomal snRNP assembly,PF12894;PF00400;,1.00E-27,CHOYP_GEMIN5.2.2,,,,,,,GEMI5_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; protein complex assembly [GO:0006461]; spliceosomal snRNP assembly [GO:0000387]" comp120100_c0_seq1,1058,40.8318,0.54705172,34,54,,,,,,,,,3.00E-11,CHOYP_LOC579914.1.1,,,,,,,,, comp120102_c0_seq1,806,40.0744,1.39341017,53,56,,4.00E-23,O53454,3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (Cholesterol dehydrogenase) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (3-beta-HSD) (3BHSD) (EC 1.1.1.145) (3-beta hydroxysterol dehydrogenase) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)],,GO:0003854; GO:0070403; GO:0005829; GO:0016042; GO:0005886; GO:0006694; GO:0004769; GO:0008202; GO:0030283,3-beta-hydroxy-delta5-steroid dehydrogenase activity; NAD+ binding; cytosol; lipid catabolic process; plasma membrane; steroid biosynthetic process; steroid delta-isomerase activity; steroid metabolic process; testosterone dehydrogenase [NAD(P)] activity,,,,,,,,,,3BHS_MYCTU,, comp120110_c0_seq1,2003,43.4348,0.48865365,110,66,,0,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,2.00E-104,CHOYP_LOC100748709.1.1,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp120113_c0_seq1,1362,39.207,0.77814611,41,118,,3.00E-38,Q32L09,UPF0515 protein C19orf66 homolog,Repressor of yield of DENV protein homolog (RyDEN),,,PF15135;,,,,,,,,,CS066_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; negative regulation of viral genome replication [GO:0045071]; response to interferon-gamma [GO:0034341]; response to type III interferon [GO:0034342]; response to type I interferon [GO:0034340] comp120113_c0_seq2,964,39.9378,0.76079355,0,4,,1.00E-33,A7YY07,UPF0515 protein C19orf66 homolog,Repressor of yield of DENV protein homolog,,,PF15135;,,,,,,,,,CS066_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp120114_c1_seq1,711,43.7412,0.50099437,35,32,,1.00E-60,Q6ICB0,Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Protein FAM152B),Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Protein FAM152B),GO:0005737; GO:0005634; GO:0008233; GO:0006508,cytoplasm; nucleus; peptidase activity; proteolysis,PF05903;,1.00E-52,CHOYP_LOC593529.1.1,,,,,,,DESI1_HUMAN,Homo sapiens (Human), comp120120_c0_seq1,816,40.3186,0.73603714,67,94,,5.00E-25,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,1.00E-14,CHOYP_HSPA12A.2.27,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp120127_c0_seq1,786,47.4555,0.3873262,26,53,,4.00E-60,Q8CBW3,Abl interactor 1 (Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1),Abl interactor 1 (Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1),GO:0030054; GO:0006928; GO:0005737; GO:0005856; GO:0030175; GO:0030426; GO:0005622; GO:0030027; GO:0072673; GO:0035855; GO:0043005; GO:0005634; GO:0018108; GO:0030296; GO:0001756; GO:0045202,cell junction; cellular component movement; cytoplasm; cytoskeleton; filopodium; growth cone; intracellular; lamellipodium; lamellipodium morphogenesis; megakaryocyte development; neuron projection; nucleus; peptidyl-tyrosine phosphorylation; protein tyrosine kinase activator activity; somitogenesis; synapse,PF07815;PF00018;,8.00E-80,CHOYP_ABI2.2.2,,,,,,,ABI1_MOUSE,Mus musculus (Mouse),dendrite morphogenesis [GO:0048813]; lamellipodium morphogenesis [GO:0072673]; megakaryocyte development [GO:0035855]; peptidyl-tyrosine phosphorylation [GO:0018108]; somitogenesis [GO:0001756] comp120130_c0_seq3,807,45.4771,0.47992471,14,16,,8.00E-20,P35832,Tyrosine-protein phosphatase 99A (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 99A) (DPTP99A),Tyrosine-protein phosphatase 99A (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 99A) (DPTP99A),GO:0030424; GO:0007415; GO:0016021; GO:0008045; GO:0005886; GO:0005001,axon; defasciculation of motor neuron axon; integral to membrane; motor neuron axon guidance; plasma membrane; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF00102;,,,,,,,,,PTP99_DROME,Drosophila melanogaster (Fruit fly),axonal defasciculation [GO:0007414]; defasciculation of motor neuron axon [GO:0007415]; motor neuron axon guidance [GO:0008045]; protein dephosphorylation [GO:0006470]; regulation of glucose metabolic process [GO:0010906] comp120140_c0_seq2,903,40.8638,0.82593676,4,164,,1.00E-19,P47967,Galectin-5 (Gal-5) (RL-18),Galectin-5 (Gal-5) (RL-18),GO:0030246,carbohydrate binding,PF00337;,,,,,,,,,LEG5_RAT,Rattus norvegicus (Rat), comp120141_c0_seq1,986,36.6126,0.39714663,437,2351,,6.00E-46,Q63829,COMM domain-containing protein 3 (Bmi-1 upstream gene protein) (Bup protein),COMM domain-containing protein 3 (Bmi-1 upstream gene protein) (Bup protein),,,PF07258;,2.00E-32,CHOYP_ISCW_ISCW008596.2.2,,,,,,,COMD3_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; sodium ion transport [GO:0006814]; transcription, DNA-templated [GO:0006351]" comp120147_c0_seq1,667,43.4783,0.41399788,27,56,,4.00E-19,Q6GQV7,Erythroid differentiation-related factor 1,Erythroid differentiation-related factor 1,GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,EDRF1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120147_c2_seq1,648,43.3642,0.33028068,19,109,,4.00E-55,Q5R9R1,Erythroid differentiation-related factor 1,Erythroid differentiation-related factor 1,GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,6.00E-49,CHOYP_EDRF1.2.2,,,,,,,EDRF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120153_c0_seq2,1361,42.2483,0.46481141,20,43,,4.00E-94,Q805A1,Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5),Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5),GO:0005524; GO:0016605; GO:0030915; GO:0051301; GO:0090398; GO:0000781; GO:0000724; GO:0007067; GO:0034184; GO:0045842; GO:0000722,"ATP binding; PML body; Smc5-Smc6 complex; cell division; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; mitosis; positive regulation of maintenance of mitotic sister chromatid cohesion; positive regulation of mitotic metaphase/anaphase transition; telomere maintenance via recombination",,4.00E-42,CHOYP_SMC5.1.1,,,,,,,SMC5_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722] comp120154_c0_seq1,1243,37.9726,0.26804585,255,40,,3.00E-67,Q9NPC3,E3 ubiquitin-protein ligase CCNB1IP1 (EC 6.3.2.-) (Cyclin-B1-interacting protein 1) (Human enhancer of invasion 10),E3 ubiquitin-protein ligase CCNB1IP1 (EC 6.3.2.-) (Cyclin-B1-interacting protein 1) (Human enhancer of invasion 10),GO:0006915; GO:0001825; GO:0051026; GO:0005694; GO:0016874; GO:0005634; GO:0035265; GO:0016567; GO:0007286; GO:0008270,apoptotic process; blastocyst formation; chiasma assembly; chromosome; ligase activity; nucleus; organ growth; protein ubiquitination; spermatid development; zinc ion binding,PF14634;,2.00E-14,CHOYP_BRAFLDRAFT_237296.1.1,,,,,,,CIP1_HUMAN,Homo sapiens (Human),blastocyst formation [GO:0001825]; chiasma assembly [GO:0051026]; protein ubiquitination [GO:0016567]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286] comp120165_c0_seq1,472,41.7373,0.83146934,21,36,,1.00E-12,P52183,Annulin (Protein-glutamine gamma-glutamyltransferase) (EC 2.3.2.13) (Transglutaminase),Annulin (Protein-glutamine gamma-glutamyltransferase) (EC 2.3.2.13) (Transglutaminase),GO:0046872; GO:0018149; GO:0005886; GO:0003810,metal ion binding; peptide cross-linking; plasma membrane; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,ANNU_SCHAM,Schistocerca americana (American grasshopper),peptide cross-linking [GO:0018149] comp120180_c0_seq1,262,54.5802,1.03749046,0,6,,9.00E-57,Q6A6M1,Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS),Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS),GO:0005524; GO:0005737; GO:0004818; GO:0006424; GO:0000049,ATP binding; cytoplasm; glutamate-tRNA ligase activity; glutamyl-tRNA aminoacylation; tRNA binding,PF00749;,,,,,,,,,SYE_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glutamyl-tRNA aminoacylation [GO:0006424] comp120180_c1_seq1,206,57.767,1.35258869,0,17,,2.00E-20,A6TWK7,Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS),Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS),GO:0005524; GO:0005737; GO:0004818; GO:0006424; GO:0046872; GO:0000049,ATP binding; cytoplasm; glutamate-tRNA ligase activity; glutamyl-tRNA aminoacylation; metal ion binding; tRNA binding,PF00749;,,,,,,,,,SYE_ALKMQ,Alkaliphilus metalliredigens (strain QYMF),glutamyl-tRNA aminoacylation [GO:0006424] comp120183_c0_seq1,1501,44.7702,0.56106074,59,64,,5.00E-94,Q5ZI11,Leucine-rich repeat-containing protein 45,Leucine-rich repeat-containing protein 45,,,PF13516;,1.00E-30,CHOYP_LOC100376045.1.1,,,,,,,LRC45_CHICK,Gallus gallus (Chicken), comp120188_c0_seq1,853,40.0938,0.54018418,38,206,,4.00E-13,Q8BZ20,Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),GO:0003950; GO:0046872; GO:0005634,NAD+ ADP-ribosyltransferase activity; metal ion binding; nucleus,PF00644;PF02825;PF00642;,,,,,,,,,PAR12_MOUSE,Mus musculus (Mouse), comp120194_c0_seq1,594,41.0774,0.36221694,16,36,,2.00E-54,A4FUB8,Transmembrane protein 115,Transmembrane protein 115,GO:0005794; GO:0016021; GO:0005634,Golgi apparatus; integral to membrane; nucleus,PF08551;,4.00E-56,CHOYP_ISCW_ISCW018298.1.1,,,,,,,TM115_BOVIN,Bos taurus (Bovine),"protein glycosylation [GO:0006486]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp120210_c0_seq1,690,42.8986,0.59949898,231,489,,4.00E-56,Q8BU85,"Methionine-R-sulfoxide reductase B3, mitochondrial (MsrB3) (EC 1.8.4.-)","Methionine-R-sulfoxide reductase B3, mitochondrial (MsrB3) (EC 1.8.4.-)",GO:0005783; GO:0005739; GO:0033743; GO:0030091; GO:0008270,endoplasmic reticulum; mitochondrion; peptide-methionine (R)-S-oxide reductase activity; protein repair; zinc ion binding,PF01641;,2.00E-16,CHOYP_MSRB3.2.4,9.00E-76,ruditapes2_c5648,,,,,MSRB3_MOUSE,Mus musculus (Mouse),protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp120230_c0_seq1,545,40.7339,0.85187077,17,119,,,,,,,,,,,1.00E-15,ruditapes_c13634,,,,,,, comp120237_c0_seq1,593,37.4368,0.93080677,127,657,,3.00E-29,P80928,Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase),Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase),GO:0030330; GO:0007569; GO:0008283; GO:0009986; GO:0007166; GO:0042056; GO:0005737; GO:0004167; GO:0005615; GO:0006954; GO:0045087; GO:0043518; GO:0090344; GO:0071157; GO:0032269; GO:0010629; GO:1902166; GO:0002906; GO:0033033; GO:0050178; GO:0030890; GO:0070374; GO:0043406; GO:0090238; GO:2000343; GO:0050715; GO:0048146; GO:0031666; GO:0061081; GO:0033138; GO:0050731; GO:0061078; GO:0010739; GO:0001516; GO:0070207,"DNA damage response, signal transduction by p53 class mediator; cell aging; cell proliferation; cell surface; cell surface receptor signaling pathway; chemoattractant activity; cytoplasm; dopachrome isomerase activity; extracellular space; inflammatory response; innate immune response; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of cell aging; negative regulation of cell cycle arrest; negative regulation of cellular protein metabolic process; negative regulation of gene expression; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of mature B cell apoptotic process; negative regulation of myeloid cell apoptotic process; phenylpyruvate tautomerase activity; positive regulation of B cell proliferation; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAP kinase activity; positive regulation of arachidonic acid secretion; positive regulation of chemokine (C-X-C motif) ligand 2 production; positive regulation of cytokine secretion; positive regulation of fibroblast proliferation; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of myeloid leukocyte cytokine production involved in immune response; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of prostaglandin secretion involved in immune response; positive regulation of protein kinase A signaling cascade; prostaglandin biosynthetic process; protein homotrimerization",PF01187;,,,,,,,,,MIF_PIG,Sus scrofa (Pig),"cell aging [GO:0007569]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]" comp120254_c1_seq1,809,45.9827,0.7036962,4,178,,,,,,,,,2.00E-18,CHOYP_BRAFLDRAFT_89952.1.1,,,,,,,,, comp120260_c0_seq1,321,43.6137,0.78922335,5,37,,6.00E-43,O88630,Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28),Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28),GO:0006888; GO:0000139; GO:0005801; GO:0016021; GO:0015031; GO:0042147,"ER to Golgi vesicle-mediated transport; Golgi membrane; cis-Golgi network; integral to membrane; protein transport; retrograde transport, endosome to Golgi",,,,,,,,,,GOSR1_MOUSE,Mus musculus (Mouse),"ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of vesicle targeting, to, from or within Golgi [GO:0048209]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion [GO:0006906]" comp120260_c1_seq2,293,36.5188,0.6255392,6,14,,,,,,,,,4.00E-59,CHOYP_LOC593134.1.1,,,,,,,,, comp120264_c0_seq1,1270,41.3386,0.38888913,71,86,,3.00E-123,Q5ZKA2,"Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)","Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)",GO:0005524; GO:0002161; GO:0004822; GO:0006428; GO:0005759; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; isoleucine-tRNA ligase activity; isoleucyl-tRNA aminoacylation; mitochondrial matrix; regulation of translational fidelity,PF08264;PF00133;,1.00E-22,CHOYP_SYIM.2.2,,,,,,,SYIM_CHICK,Gallus gallus (Chicken),isoleucyl-tRNA aminoacylation [GO:0006428] comp120264_c2_seq1,1185,41.0127,0.32136046,44,32,,9.00E-131,Q8BIJ6,"Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)","Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)",GO:0005524; GO:0002161; GO:0004822; GO:0006428; GO:0005759; GO:0005739; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; isoleucine-tRNA ligase activity; isoleucyl-tRNA aminoacylation; mitochondrial matrix; mitochondrion; regulation of translational fidelity,PF08264;PF00133;,1.00E-35,CHOYP_SYIM.1.2,,,,,,,SYIM_MOUSE,Mus musculus (Mouse),isoleucyl-tRNA aminoacylation [GO:0006428] comp120273_c0_seq1,800,42.875,0.57249426,18,61,,6.00E-34,Q17R06,Ras-related protein Rab-21,Ras-related protein Rab-21,GO:0019003; GO:0005525; GO:0003924; GO:0000139; GO:0030659; GO:0031901; GO:0005789; GO:0015031; GO:0007264,GDP binding; GTP binding; GTPase activity; Golgi membrane; cytoplasmic vesicle membrane; early endosome membrane; endoplasmic reticulum membrane; protein transport; small GTPase mediated signal transduction,PF00071;,4.00E-45,CHOYP_LOC100115628.1.1,,,,,,,RAB21_BOVIN,Bos taurus (Bovine),protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264] comp120278_c0_seq2,1055,39.8104,0.37270622,32,65,,2.00E-23,Q96EH3,Mitochondrial assembly of ribosomal large subunit protein 1,Mitochondrial assembly of ribosomal large subunit protein 1,GO:0005759; GO:0005739; GO:0070130; GO:0042273,mitochondrial matrix; mitochondrion; negative regulation of mitochondrial translation; ribosomal large subunit biogenesis,,,,,,,,,,MASU1_HUMAN,Homo sapiens (Human),negative regulation of mitochondrial translation [GO:0070130]; negative regulation of ribosome biogenesis [GO:0090071]; ribosomal large subunit biogenesis [GO:0042273] comp120284_c2_seq1,724,44.6133,0.75069172,35,11,,1.00E-64,Q811G0,Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),GO:0034464; GO:0036064; GO:0060170; GO:0005737; GO:0045444; GO:0005634,BBSome; cilium basal body; cilium membrane; cytoplasm; fat cell differentiation; nucleus,PF14728;PF14727;,5.00E-69,CHOYP_PTHB1.1.1,,,,,,,PTHB1_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; fat cell differentiation [GO:0045444]; protein localization to cilium [GO:0061512]; protein transport [GO:0015031] comp120288_c2_seq1,1616,43.3787,0.40817389,36,6,,0,Q15386,Ubiquitin-protein ligase E3C (EC 6.3.2.-) (HectH2),Ubiquitin-protein ligase E3C (EC 6.3.2.-) (HectH2),GO:0005737; GO:0005634; GO:0000502; GO:0000209; GO:0042787; GO:0004842,cytoplasm; nucleus; proteasome complex; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,0,CHOYP_UBE3C.1.1,,,,,,,UBE3C_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp120288_c2_seq2,1113,45.0135,0.42615355,0,0,,2.00E-49,P51593,"E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (HECT, UBA and WWE domain-containing protein 1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) (Fragment)","E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (HECT, UBA and WWE domain-containing protein 1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) (Fragment)",GO:0003677; GO:0006284; GO:0030154; GO:0005737; GO:0016574; GO:0005634; GO:0006513; GO:0000209; GO:0042787; GO:0004842,DNA binding; base-excision repair; cell differentiation; cytoplasm; histone ubiquitination; nucleus; protein monoubiquitination; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,3.00E-144,CHOYP_LOC100374388.1.2,,,,,,,HUWE1_RAT,Rattus norvegicus (Rat),base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp120291_c0_seq1,441,42.1769,0.40902466,12,18,,2.00E-42,P86410,Ral GTPase-activating protein subunit beta (p170),Ral GTPase-activating protein subunit beta (p170),GO:0017123; GO:0032859; GO:0046982,Ral GTPase activator activity; activation of Ral GTPase activity; protein heterodimerization activity,,,,,,,,,,RLGPB_RAT,Rattus norvegicus (Rat),activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] comp120291_c1_seq1,1499,47.8986,0.46556039,17,40,,4.00E-126,Q8BQZ4,Ral GTPase-activating protein subunit beta (p170),Ral GTPase-activating protein subunit beta (p170),GO:0017123; GO:0032484; GO:0032859; GO:0005829; GO:0046982; GO:0060178,Ral GTPase activator activity; Ral protein signal transduction; activation of Ral GTPase activity; cytosol; protein heterodimerization activity; regulation of exocyst localization,,3.00E-95,CHOYP_BRAFLDRAFT_116449.1.1,,,,,,,RLGPB_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; membrane organization [GO:0061024]; Ral protein signal transduction [GO:0032484]; regulation of exocyst localization [GO:0060178]; regulation of protein localization [GO:0032880]; regulation of small GTPase mediated signal transduction [GO:0051056] comp120296_c3_seq1,617,38.0875,1.17714595,3,88,,1.00E-07,O88917,Latrophilin-1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1),Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1),GO:0004930; GO:0030424; GO:0007420; GO:0035584; GO:0030246; GO:0050839; GO:0030054; GO:0030426; GO:0007157; GO:0016021; GO:0016524; GO:0007218; GO:0090129; GO:0014069; GO:0042734; GO:0016079; GO:0015643,G-protein coupled receptor activity; axon; brain development; calcium-mediated signaling using intracellular calcium source; carbohydrate binding; cell adhesion molecule binding; cell junction; growth cone; heterophilic cell-cell adhesion; integral to membrane; latrotoxin receptor activity; neuropeptide signaling pathway; positive regulation of synapse maturation; postsynaptic density; presynaptic membrane; synaptic vesicle exocytosis; toxic substance binding,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,,,,,,,,,LPHN1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse maturation [GO:0090129]; synaptic vesicle exocytosis [GO:0016079] comp120298_c0_seq2,524,48.0916,0.96507704,0,86,,5.00E-08,P11602,Lipoprotein lipase (LPL) (EC 3.1.1.34),Lipoprotein lipase (LPL) (EC 3.1.1.34),GO:0031225; GO:0009986; GO:0042627; GO:0008201; GO:0004465; GO:0005886; GO:0010886; GO:0010744; GO:0010890; GO:0019433; GO:0070328; GO:0004806; GO:0034361,anchored to membrane; cell surface; chylomicron; heparin binding; lipoprotein lipase activity; plasma membrane; positive regulation of cholesterol storage; positive regulation of macrophage derived foam cell differentiation; positive regulation of sequestering of triglyceride; triglyceride catabolic process; triglyceride homeostasis; triglyceride lipase activity; very-low-density lipoprotein particle,PF00151;PF01477;,,,7.00E-19,ruditapes_c611,,,,,LIPL_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of sequestering of triglyceride [GO:0010890]; triglyceride catabolic process [GO:0019433]; triglyceride homeostasis [GO:0070328]; very-low-density lipoprotein particle remodeling [GO:0034372] comp120302_c0_seq1,426,48.3568,0.45107326,17,6,,4.00E-26,Q9VUI3,Echinoderm microtubule-associated protein-like CG42247,Echinoderm microtubule-associated protein-like CG42247,GO:0008344; GO:0005737; GO:0035556; GO:0035011; GO:0005874; GO:0008017; GO:0071683; GO:0007605,adult locomotory behavior; cytoplasm; intracellular signal transduction; melanotic encapsulation of foreign target; microtubule; microtubule binding; sensory dendrite; sensory perception of sound,PF03607;PF03451;PF00400;,,,,,,,,,EMAL_DROME,Drosophila melanogaster (Fruit fly),adult locomotory behavior [GO:0008344]; intracellular signal transduction [GO:0035556]; melanotic encapsulation of foreign target [GO:0035011]; microtubule-based process [GO:0007017]; sensory perception of sound [GO:0007605] comp120302_c1_seq1,818,47.1883,0.45948062,37,32,,3.00E-120,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,7.00E-119,CHOYP_EMAL6.1.1,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp120308_c1_seq1,236,55.5085,0.9391777,0,14,,2.00E-24,A4D161,Protein FAM221A,Protein FAM221A,,,PF14753;,,,,,,,,,F221A_HUMAN,Homo sapiens (Human), comp120308_c2_seq1,622,40.9968,1.31028422,0,120,,,,,,,,,4.00E-12,CHOYP_BRAFLDRAFT_239751.1.3,,,,,,,,, comp120312_c0_seq1,939,40.3621,0.40654974,154,293,,3.00E-57,O43290,U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1),U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1),GO:0015030; GO:0005794; GO:0071013; GO:0007050; GO:0005829; GO:0097193; GO:0045585; GO:0000387,Cajal body; Golgi apparatus; catalytic step 2 spliceosome; cell cycle arrest; cytosol; intrinsic apoptotic signaling pathway; positive regulation of cytotoxic T cell differentiation; spliceosomal snRNP assembly,PF03343;,2.00E-43,CHOYP_SART1.1.1,,,,,,,SNUT1_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; intrinsic apoptotic signaling pathway [GO:0097193]; maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387]" comp120322_c0_seq1,377,44.0318,0.28361544,0,22,,3.00E-40,Q5E9N4,"Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)","Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)",GO:0047536; GO:0006103; GO:0033512; GO:0009058; GO:0006536; GO:0016212; GO:0005739; GO:0030170,2-aminoadipate transaminase activity; 2-oxoglutarate metabolic process; L-lysine catabolic process to acetyl-CoA via saccharopine; biosynthetic process; glutamate metabolic process; kynurenine-oxoglutarate transaminase activity; mitochondrion; pyridoxal phosphate binding,PF00155;,,,,,,,,,AADAT_BOVIN,Bos taurus (Bovine),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512] comp120326_c0_seq3,861,39.2567,0.57634592,0,0,,9.00E-29,Q8BIG4,F-box only protein 28,F-box only protein 28,,,PF00646;,,,,,,,,,FBX28_MOUSE,Mus musculus (Mouse), comp120326_c0_seq4,686,41.691,0.6049915,0,0,,,,,,,,,5.00E-31,CHOYP_FBX28.1.1,,,,,,,,, comp120333_c0_seq1,552,45.1087,0.83348897,0,110,,2.00E-41,Q9W6V5,Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Supporting-cell antigen),Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Supporting-cell antigen),GO:0005911; GO:0016021; GO:0043407; GO:0050860; GO:0042059; GO:0051898; GO:0035335; GO:0016791; GO:0005886; GO:0048008; GO:0051894; GO:0004725; GO:0032587,cell-cell junction; integral to membrane; negative regulation of MAP kinase activity; negative regulation of T cell receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of protein kinase B signaling cascade; peptidyl-tyrosine dephosphorylation; phosphatase activity; plasma membrane; platelet-derived growth factor receptor signaling pathway; positive regulation of focal adhesion assembly; protein tyrosine phosphatase activity; ruffle membrane,PF00041;PF00102;,4.00E-12,CHOYP_PTPRK.17.20,,,,,,,PTPRJ_CHICK,Gallus gallus (Chicken),negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell receptor signaling pathway [GO:0050860]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell adhesion [GO:0045785]; positive regulation of focal adhesion assembly [GO:0051894] comp120334_c0_seq1,543,47.8821,0.3502684,21,19,,2.00E-09,O75970,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0016327; GO:0007155; GO:0005737; GO:0031410; GO:0030425; GO:0019048; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; apicolateral plasma membrane; cell adhesion; cytoplasm; cytoplasmic vesicle; dendrite; modulation by virus of host morphology or physiology; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,,,,,,,,,MPDZ_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032] comp120343_c0_seq2,1862,39.7959,0.65094358,8,16,,2.00E-116,Q8N6G5,"Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2)","Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2)",GO:0032580; GO:0008376; GO:0030206; GO:0050653; GO:0050652; GO:0047237; GO:0030173; GO:0046872,"Golgi cisterna membrane; acetylgalactosaminyltransferase activity; chondroitin sulfate biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; integral to Golgi membrane; metal ion binding",PF05679;,3.00E-20,CHOYP_LOC659298.1.1,,,,,,,CGAT2_HUMAN,Homo sapiens (Human),"chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050652]; proteoglycan biosynthetic process [GO:0030166]" comp120344_c1_seq1,1203,42.394,0.42877523,62,76,,2.00E-144,Q8N2I9,Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495),Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495),GO:0005524; GO:0005737; GO:0005634; GO:0004674,ATP binding; cytoplasm; nucleus; protein serine/threonine kinase activity,PF00069;,5.00E-135,CHOYP_STK40.1.1,1.00E-27,ruditapes_c21684,,,,,STK40_HUMAN,Homo sapiens (Human),glycogen metabolic process [GO:0005977]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; regulation of gene expression [GO:0010468]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016] comp120348_c0_seq2,1046,30.4015,1.3573532,93,11,,6.00E-13,P91889,FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,,,,,,,,,FMRF_SEPOF,Sepia officinalis (Common cuttlefish),neuropeptide signaling pathway [GO:0007218] comp120352_c0_seq1,736,43.4783,0.80723041,16,53,,5.00E-78,P42260,"Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6)","Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6)",GO:0030054; GO:0032839; GO:0005234; GO:0008328; GO:0015277; GO:0051967; GO:0051402; GO:0043204; GO:0043525; GO:0045211; GO:0042803; GO:0043113; GO:0046328; GO:0007268; GO:0043195,"cell junction; dendrite cytoplasm; extracellular-glutamate-gated ion channel activity; ionotropic glutamate receptor complex; kainate selective glutamate receptor activity; negative regulation of synaptic transmission, glutamatergic; neuron apoptotic process; perikaryon; positive regulation of neuron apoptotic process; postsynaptic membrane; protein homodimerization activity; receptor clustering; regulation of JNK cascade; synaptic transmission; terminal bouton",PF01094;PF00060;PF10613;,2.00E-35,CHOYP_LOC100533316.2.2,,,,,,,GRIK2_RAT,Rattus norvegicus (Rat),"behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; intracellular protein transport [GO:0006886]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]" comp120352_c0_seq2,284,45.4225,0.75908931,0,0,,3.00E-10,Q91755,"Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)","Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)",GO:0030054; GO:0005234; GO:0016021; GO:0004970; GO:0035235; GO:0045211,cell junction; extracellular-glutamate-gated ion channel activity; integral to membrane; ionotropic glutamate receptor activity; ionotropic glutamate receptor signaling pathway; postsynaptic membrane,PF00060;,,,,,,,,,GRIK2_XENLA,Xenopus laevis (African clawed frog), comp120365_c0_seq1,728,42.9945,0.53668813,16,79,,2.00E-14,Q0KI50,"Dystrophin, isoform D (Protein detached)","Dystrophin, isoform D (Protein detached)",GO:0003779; GO:0005509; GO:0005737; GO:0005856; GO:0016010; GO:0030010; GO:0008586; GO:0007474; GO:0046716; GO:0007517; GO:0007274; GO:0046928; GO:0048172; GO:0042383; GO:0005198; GO:0045202; GO:0008270,actin binding; calcium ion binding; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; establishment of cell polarity; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; muscle cell cellular homeostasis; muscle organ development; neuromuscular synaptic transmission; regulation of neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity; sarcolemma; structural molecule activity; synapse; zinc ion binding,PF09068;PF09069;PF00569;,2.00E-16,CHOYP_DLP.1.1,,,,,,,DMDD_DROME,Drosophila melanogaster (Fruit fly),establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172] comp120369_c0_seq1,970,40,1.10965648,11,270,,9.00E-25,O73823,T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Stem cell leukemia protein SCL) (xSCL),T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Stem cell leukemia protein SCL) (xSCL),GO:0003677; GO:0030218; GO:0005634; GO:0003700; GO:0006351,"DNA binding; erythrocyte differentiation; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00010;,,,,,,,,,TAL1_XENLA,Xenopus laevis (African clawed frog),"erythrocyte differentiation [GO:0030218]; hemopoiesis [GO:0030097]; transcription, DNA-templated [GO:0006351]" comp120375_c0_seq1,470,44.8936,0.63511614,0,0,,8.00E-30,Q8SX83,Protein split ends,Protein split ends,GO:0003723; GO:0016055; GO:0007411; GO:0048749; GO:0050832; GO:0007173; GO:0048106; GO:0007403; GO:0008586; GO:0035321; GO:0007400; GO:0000166; GO:0005634; GO:0007422; GO:0030177; GO:0006355; GO:0007379; GO:0006351; GO:0035222,"RNA binding; Wnt receptor signaling pathway; axon guidance; compound eye development; defense response to fungus; epidermal growth factor receptor signaling pathway; establishment of thoracic bristle planar orientation; glial cell fate determination; imaginal disc-derived wing vein morphogenesis; maintenance of imaginal disc-derived wing hair orientation; neuroblast fate determination; nucleotide binding; nucleus; peripheral nervous system development; positive regulation of Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; segment specification; transcription, DNA-dependent; wing disc pattern formation",PF00076;PF07744;,,,,,,,,,SPEN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; compound eye development [GO:0048749]; defense response to fungus [GO:0050832]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of thoracic bristle planar orientation [GO:0048106]; glial cell fate determination [GO:0007403]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maintenance of imaginal disc-derived wing hair orientation [GO:0035321]; mRNA splicing, via spliceosome [GO:0000398]; neuroblast fate determination [GO:0007400]; peripheral nervous system development [GO:0007422]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sleep [GO:0030431]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]; Wnt signaling pathway [GO:0016055]" comp120377_c0_seq2,711,37.4121,0.45011583,14,60,,5.00E-19,Q5NVE2,Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein),Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein),GO:0048471; GO:0006355; GO:0006351,"perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09073;,,,,,,,,,SRFB1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120380_c0_seq1,801,43.8202,0.47007563,20,0,,4.00E-43,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp120390_c0_seq2,458,39.9563,0.3838728,2,0,,5.00E-12,O94451,E3 SUMO-protein ligase pli1 (EC 6.3.2.-),E3 SUMO-protein ligase pli1 (EC 6.3.2.-),GO:0019789; GO:0030999; GO:0003676; GO:0005634; GO:0016925; GO:0007131; GO:0051983; GO:0000019; GO:0010520; GO:0032204; GO:0035861; GO:0008270,SUMO ligase activity; linear element assembly; nucleic acid binding; nucleus; protein sumoylation; reciprocal meiotic recombination; regulation of chromosome segregation; regulation of mitotic recombination; regulation of reciprocal meiotic recombination; regulation of telomere maintenance; site of double-strand break; zinc ion binding,PF14324;PF02037;PF02891;,,,,,,,,,PLI1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),linear element assembly [GO:0030999]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein sumoylation [GO:0016925]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; regulation of reciprocal meiotic recombination [GO:0010520]; regulation of telomere maintenance via recombination [GO:0032207] comp120390_c0_seq4,1071,42.3903,0.49964116,30,15,,3.00E-21,O70260,E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (KChAP) (Potassium channel-associated protein) (Protein inhibitor of activated STAT protein 3),E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (KChAP) (Potassium channel-associated protein) (Protein inhibitor of activated STAT protein 3),GO:0019789; GO:0005737; GO:0030425; GO:0016607; GO:0003676; GO:0005634; GO:0010628; GO:0045838; GO:0033235; GO:0015459; GO:0008022; GO:0047485; GO:0016925; GO:0006355; GO:0009725; GO:0045202; GO:0006351; GO:0008270,"SUMO ligase activity; cytoplasm; dendrite; nuclear speck; nucleic acid binding; nucleus; positive regulation of gene expression; positive regulation of membrane potential; positive regulation of protein sumoylation; potassium channel regulator activity; protein C-terminus binding; protein N-terminus binding; protein sumoylation; regulation of transcription, DNA-dependent; response to hormone stimulus; synapse; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS3_RAT,Rattus norvegicus (Rat),"negative regulation of protein sumoylation [GO:0033234]; positive regulation of gene expression [GO:0010628]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of transcription, DNA-templated [GO:0006355]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp120395_c1_seq1,383,43.6031,0.77733323,0,44,,1.00E-11,O88627,Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2),Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2),GO:0005887; GO:0001882; GO:0005415; GO:0015211,integral to plasma membrane; nucleoside binding; nucleoside:sodium symporter activity; purine nucleoside transmembrane transporter activity,PF07670;PF07662;PF01773;,,,,,,,,,S28A2_MOUSE,Mus musculus (Mouse),purine nucleoside transmembrane transport [GO:0015860] comp120395_c4_seq1,1064,39.4737,1.06312193,0,144,,7.00E-32,Q9UA35,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),GO:0016021; GO:0005415,integral to membrane; nucleoside:sodium symporter activity,PF07670;PF07662;PF01773;,,,1.00E-32,ruditapes_c14118,,,,,S28A3_EPTST,Eptatretus stoutii (Pacific hagfish), comp120399_c0_seq2,228,41.2281,0.31157062,101,189,,,,,,,,,,,1.00E-11,ruditapes_lrc6950,,,,,,, comp120400_c0_seq1,966,37.9917,0.50718924,0,9,,2.00E-47,Q9H977,WD repeat-containing protein 54,WD repeat-containing protein 54,,,,,,,,,,,,WDR54_HUMAN,Homo sapiens (Human), comp120400_c0_seq2,918,37.4728,0.54582044,0,0,,4.00E-07,Q4I7X1,Polyadenylation factor subunit 2,Polyadenylation factor subunit 2,GO:0051301; GO:0007059; GO:0006397; GO:0007067; GO:0005634,cell division; chromosome segregation; mRNA processing; mitosis; nucleus,PF00400;,,,,,,,,,PFS2_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),chromosome segregation [GO:0007059]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp120401_c0_seq1,1002,39.7206,0.93157988,19,69,,1.00E-17,Q5ZJU0,Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9),Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT9_CHICK,Gallus gallus (Chicken), comp120410_c0_seq1,335,36.4179,0.47659999,2,27,,7.00E-12,Q96CA5,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)],Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)],GO:0005794; GO:0007257; GO:0006309; GO:0004869; GO:0019899; GO:0043066; GO:0005634; GO:0042127; GO:0070247; GO:0004842; GO:0008270,Golgi apparatus; activation of JUN kinase activity; apoptotic DNA fragmentation; cysteine-type endopeptidase inhibitor activity; enzyme binding; negative regulation of apoptotic process; nucleus; regulation of cell proliferation; regulation of natural killer cell apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,BIRC7_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of natural killer cell apoptotic process [GO:0070247]; regulation of signal transduction [GO:0009966] comp120413_c1_seq1,422,41.9431,0.49300976,15,27,,3.00E-14,Q24372,Lachesin,Lachesin,GO:0031225; GO:0061343; GO:0007156; GO:0035160; GO:0016331; GO:0005886; GO:0042803; GO:0035151; GO:0005918; GO:0019991,"anchored to membrane; cell adhesion involved in heart morphogenesis; homophilic cell adhesion; maintenance of epithelial integrity, open tracheal system; morphogenesis of embryonic epithelium; plasma membrane; protein homodimerization activity; regulation of tube size, open tracheal system; septate junction; septate junction assembly",PF07679;,,,,,,,,,LACH_DROME,Drosophila melanogaster (Fruit fly),"cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]" comp120416_c0_seq1,1477,40.6229,0.53318928,58,238,,9.00E-144,Q13177,Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)],Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)],GO:0005524; GO:0038095; GO:0031295; GO:0050852; GO:0007411; GO:0006921; GO:0005829; GO:0045087; GO:0019048; GO:0043066; GO:2001271; GO:0006469; GO:0005634; GO:0018105; GO:0048471; GO:0005886; GO:2001238; GO:0046777; GO:0004674; GO:0030296; GO:0050690; GO:0040008; GO:0016032,ATP binding; Fc-epsilon receptor signaling pathway; T cell costimulation; T cell receptor signaling pathway; axon guidance; cellular component disassembly involved in execution phase of apoptosis; cytosol; innate immune response; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; negative regulation of protein kinase activity; nucleus; peptidyl-serine phosphorylation; perinuclear region of cytoplasm; plasma membrane; positive regulation of extrinsic apoptotic signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activator activity; regulation of defense response to virus by virus; regulation of growth; viral process,PF00786;PF00069;,5.00E-111,CHOYP_PAK1.1.1,5.00E-121,ruditapes_c16007,,,,,PAK2_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular response to organic cyclic compound [GO:0071407]; dendritic spine development [GO:0060996]; Fc-epsilon receptor signaling pathway [GO:0038095]; mitotic cell cycle [GO:0000278]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of defense response to virus by virus [GO:0050690]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032] comp120418_c1_seq1,918,34.5316,0.4780718,53,187,,2.00E-61,Q5NDE7,"Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)","Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)",GO:0008375; GO:0005783; GO:0005789; GO:0016021; GO:0006493,acetylglucosaminyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein O-linked glycosylation,PF04577;,,,,,,,,,GTDC2_XENLA,Xenopus laevis (African clawed frog),neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] comp120420_c0_seq1,1778,41.2261,1.14294075,3569,22,male>female,7.00E-30,Q6ERS4,CBL-interacting protein kinase 16 (EC 2.7.11.1) (OsCIPK16),CBL-interacting protein kinase 16 (EC 2.7.11.1) (OsCIPK16),GO:0005524; GO:0004674; GO:0007165,ATP binding; protein serine/threonine kinase activity; signal transduction,PF03822;PF00069;,9.00E-14,CHOYP_SMKX.1.1,,,,,,,CIPKG_ORYSJ,Oryza sativa subsp. japonica (Rice),signal transduction [GO:0007165] comp120422_c0_seq1,580,46.2069,0.52950716,6,75,,2.00E-25,P90893,Putative serine protease F56F10.1 (EC 3.4.-.-),Putative serine protease F56F10.1 (EC 3.4.-.-),GO:0006508; GO:0008236,proteolysis; serine-type peptidase activity,PF05577;,6.00E-23,CHOYP_BRAFLDRAFT_284130.1.1,,,,,,,YM9I_CAEEL,Caenorhabditis elegans,innate immune response [GO:0045087]; proteolysis [GO:0006508] comp120422_c0_seq2,449,41.8708,0.46022956,5,98,,3.00E-29,P34528,Putative serine protease K12H4.7 (EC 3.4.-.-),Putative serine protease K12H4.7 (EC 3.4.-.-),GO:0006508; GO:0008236,proteolysis; serine-type peptidase activity,PF05577;,,,,,,,,,YM67_CAEEL,Caenorhabditis elegans,innate immune response [GO:0045087]; proteolysis [GO:0006508] comp120422_c2_seq1,261,47.1264,0.48881315,3,46,,3.00E-11,Q1PF50,Probable serine protease EDA2 (EC 3.4.-.-) (Protein EMBRYO SAC DEVELOPMENT ARREST 2),Probable serine protease EDA2 (EC 3.4.-.-) (Protein EMBRYO SAC DEVELOPMENT ARREST 2),GO:0005576; GO:0009561; GO:0006508; GO:0008236,extracellular region; megagametogenesis; proteolysis; serine-type peptidase activity,PF05577;,,,,,,,,,EDA2_ARATH,Arabidopsis thaliana (Mouse-ear cress),megagametogenesis [GO:0009561]; proteolysis [GO:0006508] comp120446_c0_seq1,896,43.4152,0.53228744,58,185,,6.00E-86,A5PJA1,Adenylate kinase isoenzyme 6 (AK6) (EC 2.7.4.3) (Coilin-interacting nuclear ATPase protein) (Dual activity adenylate kinase/ATPase) (AK/ATPase),Adenylate kinase isoenzyme 6 (AK6) (EC 2.7.4.3) (Coilin-interacting nuclear ATPase protein) (Dual activity adenylate kinase/ATPase) (AK/ATPase),GO:0005524; GO:0015030; GO:0003677; GO:0004017,ATP binding; Cajal body; DNA binding; adenylate kinase activity,,2.00E-56,CHOYP_TAF9.1.1,,,,,,,KAD6_BOVIN,Bos taurus (Bovine), comp120448_c0_seq1,780,45.641,0.99735183,1,84,,2.00E-15,Q9CXE7,Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2),Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2),GO:0005794; GO:0090161; GO:0005801; GO:0070971; GO:0005789; GO:0005793; GO:0033116; GO:0016021; GO:0015031,Golgi apparatus; Golgi ribbon formation; cis-Golgi network; endoplasmic reticulum exit site; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; protein transport,PF01105;,,,,,,,,,TMED5_MOUSE,Mus musculus (Mouse),Golgi ribbon formation [GO:0090161]; protein transport [GO:0015031] comp120453_c0_seq1,1388,44.5245,0.34000656,47,100,,1.00E-44,Q92574,Hamartin (Tuberous sclerosis 1 protein),Hamartin (Tuberous sclerosis 1 protein),GO:0030695; GO:0033596; GO:0032862; GO:0055007; GO:0005938; GO:0007050; GO:0030030; GO:0007160; GO:0021987; GO:0030426; GO:0021766; GO:0008286; GO:0043231; GO:0001822; GO:0030027; GO:0016020; GO:0042552; GO:0032007; GO:0008285; GO:0045792; GO:0017148; GO:0001843; GO:0051894; GO:0006813; GO:0051291; GO:0050821; GO:0006407; GO:0043666; GO:0045859; GO:0051492; GO:0050808,GTPase regulator activity; TSC1-TSC2 complex; activation of Rho GTPase activity; cardiac muscle cell differentiation; cell cortex; cell cycle arrest; cell projection organization; cell-matrix adhesion; cerebral cortex development; growth cone; hippocampus development; insulin receptor signaling pathway; intracellular membrane-bounded organelle; kidney development; lamellipodium; membrane; myelination; negative regulation of TOR signaling cascade; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of translation; neural tube closure; positive regulation of focal adhesion assembly; potassium ion transport; protein heterooligomerization; protein stabilization; rRNA export from nucleus; regulation of phosphoprotein phosphatase activity; regulation of protein kinase activity; regulation of stress fiber assembly; synapse organization,PF04388;,4.00E-23,CHOYP_TSC1.1.1,,,,,,,TSC1_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; cardiac muscle cell differentiation [GO:0055007]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of macroautophagy [GO:0016242]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; potassium ion transport [GO:0006813]; protein heterooligomerization [GO:0051291]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] comp120459_c0_seq1,550,36,0.45645797,10,132,,8.00E-08,Q8NBN7,Retinol dehydrogenase 13 (EC 1.1.1.-),Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3),GO:0005739; GO:0016491,mitochondrion; oxidoreductase activity,PF00106;,,,,,,,,,RDH13_HUMAN,Homo sapiens (Human),eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842] comp120460_c0_seq1,805,42.236,0.59783507,23,18,,1.00E-123,Q9Y282,Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84),Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84),GO:0005794; GO:0005789; GO:0033116; GO:0016021; GO:0016192,Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; vesicle-mediated transport,PF07970;,1.00E-97,CHOYP_ERGI3.1.1,,,,,,,ERGI3_HUMAN,Homo sapiens (Human),vesicle-mediated transport [GO:0016192] comp120460_c1_seq1,311,36.3344,0.48903327,8,32,,5.00E-11,Q9T042,Protein disulfide-isomerase 5-4 (AtPDIL5-4) (Protein disulfide-isomerase 7) (PDI7) (Protein disulfide-isomerase 8-2) (AtPDIL8-2),Protein disulfide-isomerase 5-4 (AtPDIL5-4) (Protein disulfide-isomerase 7) (PDI7) (Protein disulfide-isomerase 8-2) (AtPDIL8-2),GO:0045454; GO:0016021,cell redox homeostasis; integral to membrane,PF07970;PF00085;,,,,,,,,,PDI54_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell redox homeostasis [GO:0045454] comp120461_c0_seq1,706,41.0765,0.31436257,33,143,,3.00E-64,A4L691,PIN2/TERF1-interacting telomerase inhibitor 1 (Pin2-interacting protein X1),PIN2/TERF1-interacting telomerase inhibitor 1 (Pin2-interacting protein X1),GO:0000781; GO:0000777; GO:0005739; GO:0007080; GO:0000228; GO:0005730; GO:0005819; GO:0007004; GO:0070034,"chromosome, telomeric region; condensed chromosome kinetochore; mitochondrion; mitotic metaphase plate congression; nuclear chromosome; nucleolus; spindle; telomere maintenance via telomerase; telomeric RNA binding",PF01585;,4.00E-20,CHOYP_LOC101168834.1.1,,,,,,,PINX1_RAT,Rattus norvegicus (Rat),"mitotic metaphase plate congression [GO:0007080]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomeric DNA binding [GO:1904744]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to nucleolus [GO:1902570]; regulation of protein stability [GO:0031647]; telomere maintenance via telomerase [GO:0007004]" comp120465_c0_seq1,488,45.2869,0.36438305,15,63,,3.00E-11,B3DIY3,Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),GO:0000724; GO:0043596; GO:0031297,double-strand break repair via homologous recombination; nuclear replication fork; replication fork processing,PF14911;PF14910;,,,,,,,,,MMS22_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] comp120465_c2_seq1,285,49.4737,0.65351864,6,13,,7.00E-10,E1C2Z0,Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),GO:0035101; GO:0042555; GO:0000724; GO:0043596; GO:0031297,FACT complex; MCM complex; double-strand break repair via homologous recombination; nuclear replication fork; replication fork processing,PF14911;PF14910;,,,,,,,,,MMS22_CHICK,Gallus gallus (Chicken),double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] comp120467_c0_seq2,965,37.2021,0.12509726,3,0,,2.00E-20,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120470_c0_seq1,437,42.1053,0.41521725,0,0,,1.00E-35,Q9ESW8,Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase),Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase),GO:0008234; GO:0005829; GO:0008233; GO:0006508,cysteine-type peptidase activity; cytosol; peptidase activity; proteolysis,PF01470;,,,,,,,,,PGPI_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp120470_c0_seq2,638,42.3197,0.39117465,4,82,,2.00E-63,Q9ESW8,Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase),Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase),GO:0008234; GO:0005829; GO:0008233; GO:0006508,cysteine-type peptidase activity; cytosol; peptidase activity; proteolysis,PF01470;,,,,,,,,,PGPI_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp120485_c0_seq1,402,41.2935,0.64386746,3,32,,,,,,,,,1.00E-36,CHOYP_BRAFLDRAFT_85626.1.1,,,,,,,,, comp120485_c1_seq1,462,40.4762,0.15925321,3,46,,5.00E-12,Q9CQK7,RWD domain-containing protein 1 (DRG family-regulatory protein 2) (IH1),RWD domain-containing protein 1 (DRG family-regulatory protein 2) (IH1),,,PF16543;PF05773;,,,,,,,,,RWDD1_MOUSE,Mus musculus (Mouse), comp120485_c2_seq1,391,45.7801,0.54444801,3,50,,4.00E-28,Q58728,Uncharacterized GTP-binding protein MJ1332,Uncharacterized GTP-binding protein MJ1332,GO:0005525,GTP binding,PF01926;PF08438;PF02824;,,,,,,,,,Y1332_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii), comp120487_c0_seq1,794,41.1839,0.65427307,8,119,,9.00E-25,C0HBB2,Lysosomal protein NCU-G1,Glycosylated lysosomal membrane protein (Lysosomal protein NCU-G1),GO:0016021; GO:0005765; GO:0005764,integral to membrane; lysosomal membrane; lysosome,PF15065;,,,,,,,,,NCUG1_SALSA,Salmo salar (Atlantic salmon), comp120494_c0_seq2,1724,45.9977,1.03536162,46,200,,4.00E-93,P97677,Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1),Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1),GO:0005112; GO:0007219; GO:0009912; GO:0005509; GO:0001709; GO:0016021; GO:0005886,Notch binding; Notch signaling pathway; auditory receptor cell fate commitment; calcium ion binding; cell fate determination; integral to membrane; plasma membrane,PF01414;PF00008;PF07645;PF07657;,2.00E-22,CHOYP_BRAFLDRAFT_123438.1.2,,,,,,,DLL1_RAT,Rattus norvegicus (Rat),astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-mediated endocytosis [GO:0072583]; endothelial tip cell fate specification [GO:0097102]; lateral inhibition [GO:0046331]; marginal zone B cell differentiation [GO:0002315]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; neuron fate specification [GO:0048665]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell division [GO:0051302]; regulation of energy homeostasis [GO:2000505]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] comp120500_c0_seq2,1115,48.8789,0.78290495,0,38,,8.00E-63,Q9JHA8,von Willebrand factor A domain-containing protein 7 (Protein G7c),von Willebrand factor A domain-containing protein 7 (Protein G7c),GO:0005576,extracellular region,,,,3.00E-109,ruditapes_c16942,,,,,VWA7_MOUSE,Mus musculus (Mouse), comp120516_c0_seq1,1400,41.4286,0.98586711,101,41,,8.00E-115,P09057,Ornithine decarboxylase (ODC) (EC 4.1.1.17),Ornithine decarboxylase (ODC) (EC 4.1.1.17),GO:0005829; GO:0001822; GO:0004586; GO:0048471; GO:0008284; GO:0009446; GO:0033387; GO:0009615,cytosol; kidney development; ornithine decarboxylase activity; perinuclear region of cytoplasm; positive regulation of cell proliferation; putrescine biosynthetic process; putrescine biosynthetic process from ornithine; response to virus,PF02784;PF00278;,,,,,,,,,DCOR_RAT,Rattus norvegicus (Rat),kidney development [GO:0001822]; polyamine metabolic process [GO:0006595]; positive regulation of cell proliferation [GO:0008284]; putrescine biosynthetic process [GO:0009446]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615] comp120520_c0_seq1,506,39.3281,0.61454785,4,30,,6.00E-12,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp120520_c1_seq1,552,38.9493,0.91159418,11,28,,7.00E-51,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp120521_c0_seq2,558,44.086,0.37757636,4,2,,3.00E-08,Q2TAW0,Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2),Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2),GO:0051301; GO:0030261; GO:0007067; GO:0005634,cell division; chromosome condensation; mitosis; nucleus,PF12422;,,,,,,,,,CNDG2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; chromosome condensation [GO:0030261]; mitotic nuclear division [GO:0007067] comp120538_c0_seq1,3149,42.3944,0.48351494,2903,21,male>female,,,,,,,,0,CHOYP_BRAFLDRAFT_130097.1.1,,,,,,,,, comp120540_c1_seq1,1011,33.9268,0.51685444,43,111,,2.00E-06,Q8TF62,Probable phospholipid-transporting ATPase IM (EC 3.6.3.1) (ATPase class I type 8B member 4),Probable phospholipid-transporting ATPase IM (EC 3.6.3.1) (ATPase class I type 8B member 4) (P4-ATPase flippase complex alpha subunit ATP8B4),GO:0005524; GO:0019829; GO:0016021; GO:0000287; GO:0004012,ATP binding; cation-transporting ATPase activity; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity,PF00122;PF16212;PF16209;,1.00E-20,CHOYP_ATP8B2.1.3,,,,,,,AT8B4_HUMAN,Homo sapiens (Human),Golgi organization [GO:0007030] comp120551_c0_seq1,302,41.0596,0.79341011,58,69,,,,,,,,,4.00E-15,CHOYP_contig_039795,,,,,,,,, comp120557_c0_seq1,231,45.4545,0.84365217,2,10,,7.00E-06,O42563,Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27),Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP3AR_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),progesterone metabolic process [GO:0042448] comp120564_c0_seq1,1248,42.1474,0.3335363,59,46,,1.00E-162,A1A5G2,Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47),Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47),GO:0006284; GO:0005737; GO:0035520; GO:0004221; GO:0006511; GO:0004843,base-excision repair; cytoplasm; monoubiquitinated protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,3.00E-87,CHOYP_UBP47.2.2,,,,,,,UBP47_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp120568_c0_seq1,865,46.3584,0.66901006,0,0,,,,,,,,,,,1.00E-19,ruditapes_c27471,,,,,,, comp120568_c0_seq2,935,46.5241,0.65371503,2,7,,3.00E-06,Q710E6,SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1),SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1),GO:0016021; GO:0016020; GO:0007275; GO:0001503; GO:0032967; GO:0045669; GO:0046850; GO:0005791; GO:0030867,integral to membrane; membrane; multicellular organismal development; ossification; positive regulation of collagen biosynthetic process; positive regulation of osteoblast differentiation; regulation of bone remodeling; rough endoplasmic reticulum; rough endoplasmic reticulum membrane,PF07738;,,,,,,,,,SUCO_RAT,Rattus norvegicus (Rat),multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850] comp120571_c0_seq2,1955,46.3427,0.4698605,130,58,,2.00E-79,A4IH82,SH3 domain-binding protein 5-like (SH3BP-5-like),SH3 domain-binding protein 5-like (SH3BP-5-like),,,PF05276;,,,,,,,,,3BP5L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),intracellular signal transduction [GO:0035556]; negative regulation of protein tyrosine kinase activity [GO:0061099] comp120571_c0_seq3,616,50.1623,0.63260591,0,3,,,,,,,,,5.00E-68,CHOYP_3BP5L.1.1,,,,,,,,, comp120578_c0_seq1,1451,44.3832,0.52036482,75,53,,2.00E-42,P42787,Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (Protein silver),Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (Protein silver),GO:0005576; GO:0007476; GO:0016021; GO:0007616; GO:0004181; GO:0048471; GO:0006909; GO:0006508; GO:0042302; GO:0008270,extracellular region; imaginal disc-derived wing morphogenesis; integral to membrane; long-term memory; metallocarboxypeptidase activity; perinuclear region of cytoplasm; phagocytosis; proteolysis; structural constituent of cuticle; zinc ion binding,PF00246;,,,,,,,,,CBPD_DROME,Drosophila melanogaster (Fruit fly),chitin-based cuticle development [GO:0040003]; imaginal disc-derived wing morphogenesis [GO:0007476]; long-term memory [GO:0007616]; peptide metabolic process [GO:0006518]; phagocytosis [GO:0006909]; protein processing [GO:0016485] comp120579_c0_seq2,1076,46.6543,0.84780971,68,1177,,3.00E-54,P77735,Uncharacterized oxidoreductase YajO (EC 1.-.-.-),Uncharacterized oxidoreductase YajO (EC 1.-.-.-),GO:0016491; GO:0006772,oxidoreductase activity; thiamine metabolic process,PF00248;,2.00E-43,CHOYP_LOC587705.2.2,3.00E-59,ruditapes_c10026,,,,,YAJO_ECOLI,Escherichia coli (strain K12),thiamine metabolic process [GO:0006772] comp120579_c0_seq5,336,43.4524,0.77650457,0,47,,,,,,,,,,,5.00E-25,ruditapes2_c619,,,,,,, comp120580_c0_seq1,622,35.6913,0.56519734,22,64,,5.00E-45,Q9H5X1,MIP18 family protein FAM96A,MIP18 family protein FAM96A,GO:0007059; GO:0005737; GO:0046872,chromosome segregation; cytoplasm; metal ion binding,PF01883;,5.00E-30,CHOYP_NEMVEDRAFT_V1G246622.1.1,,,,,,,FA96A_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226] comp120581_c0_seq1,774,46.3824,0.4376066,2,0,,5.00E-117,Q9NYC9,"Dynein heavy chain 9, axonemal (Axonemal beta dynein heavy chain 9) (Ciliary dynein heavy chain 9)","Dynein heavy chain 9, axonemal (Axonemal beta dynein heavy chain 9) (Ciliary dynein heavy chain 9)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0030030; GO:0006928; GO:0035085; GO:0005874; GO:0003777; GO:0007018; GO:0007283,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; cell projection organization; cellular component movement; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement; spermatogenesis,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYH9_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; movement of cell or subcellular component [GO:0006928]; spermatogenesis [GO:0007283] comp120581_c0_seq2,787,47.141,0.4390108,20,0,,2.00E-135,P23098,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-164,CHOYP_DYHC.1.3,,,,,,,DYHC_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp120583_c0_seq1,948,39.8734,0.5605598,26,101,,3.00E-66,Q4V8B2,DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3),DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3),GO:0030308; GO:0048471; GO:0043065; GO:0010225; GO:0010332,negative regulation of cell growth; perinuclear region of cytoplasm; positive regulation of apoptotic process; response to UV-C; response to gamma radiation,PF03556;,2.00E-74,CHOYP_LOC100374641.1.1,3.00E-40,ruditapes_c10187,,,,,DCNL3_RAT,Rattus norvegicus (Rat),negative regulation of cell growth [GO:0030308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; response to gamma radiation [GO:0010332]; response to radiation [GO:0009314]; response to UV-C [GO:0010225] comp120585_c0_seq1,1585,40.1262,0.47142536,520,1948,,6.00E-160,Q9NQH7,Probable Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3),Probable Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3),GO:0004177; GO:0009987; GO:0003094; GO:0030145; GO:0008237; GO:0005739; GO:0016485; GO:0006508,aminopeptidase activity; cellular process; glomerular filtration; manganese ion binding; metallopeptidase activity; mitochondrion; protein processing; proteolysis,PF05195;PF00557;,,,5.00E-20,ruditapes_c7073,,,,,XPP3_HUMAN,Homo sapiens (Human),glomerular filtration [GO:0003094]; protein processing [GO:0016485] comp120586_c2_seq1,423,42.7896,0.48000268,6,8,,8.00E-59,Q5ZIW1,"Twinkle protein, mitochondrial (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein homolog)","Twinkle protein, mitochondrial (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein homolog)",GO:0043139; GO:0005524; GO:0006264; GO:0042645; GO:0003697,5'-3' DNA helicase activity; ATP binding; mitochondrial DNA replication; mitochondrial nucleoid; single-stranded DNA binding,,9.00E-19,CHOYP_LOC100551924.1.1,,,,,,,PEO1_CHICK,Gallus gallus (Chicken),mitochondrial DNA replication [GO:0006264] comp120600_c0_seq2,243,43.6214,0.26293549,1,34,,,,,,,,,2.00E-12,CHOYP_TTC13.1.1,,,,,,,,, comp120600_c1_seq1,388,38.1443,0.51309932,13,24,,,,,,,,,1.00E-16,CHOYP_TTC13.1.1,,,,,,,,, comp120600_c2_seq1,867,41.8685,0.53085509,27,97,,1.00E-62,Q8NBP0,Tetratricopeptide repeat protein 13 (TPR repeat protein 13),Tetratricopeptide repeat protein 13 (TPR repeat protein 13),,,PF00515;PF13181;,,,,,,,,,TTC13_HUMAN,Homo sapiens (Human), comp120601_c2_seq1,2021,40.8214,0.30255699,130,17,,6.00E-13,Q9BXK5,Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1),Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1),GO:0008656; GO:0016021; GO:0031966; GO:0005739; GO:0005634,cysteine-type endopeptidase activator activity involved in apoptotic process; integral to membrane; mitochondrial membrane; mitochondrion; nucleus,PF00452;,,,,,,,,,B2L13_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915] comp120602_c0_seq1,769,45.5137,0.31428625,0,0,,5.00E-44,P82094,TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa),TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa),GO:0003677; GO:0005794; GO:0000139; GO:0001675; GO:0071407; GO:0042742; GO:0008584; GO:0010629; GO:0005634; GO:0001819; GO:0061136; GO:0006355; GO:0030317; GO:0007289; GO:0003712; GO:0006366,"DNA binding; Golgi apparatus; Golgi membrane; acrosome assembly; cellular response to organic cyclic compound; defense response to bacterium; male gonad development; negative regulation of gene expression; nucleus; positive regulation of cytokine production; regulation of proteasomal protein catabolic process; regulation of transcription, DNA-dependent; sperm motility; spermatid nucleus differentiation; transcription cofactor activity; transcription from RNA polymerase II promoter",PF12329;PF12325;,6.00E-24,CHOYP_TMF1.1.1,,,,,,,TMF1_HUMAN,Homo sapiens (Human),"acrosome assembly [GO:0001675]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; spermatid nucleus differentiation [GO:0007289]; sperm motility [GO:0030317]; transcription from RNA polymerase II promoter [GO:0006366]" comp120602_c0_seq2,1005,45.3731,0.35829082,26,4,,4.00E-45,P82094,TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa),TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa),GO:0003677; GO:0005794; GO:0000139; GO:0001675; GO:0071407; GO:0042742; GO:0008584; GO:0010629; GO:0005634; GO:0001819; GO:0061136; GO:0006355; GO:0030317; GO:0007289; GO:0003712; GO:0006366,"DNA binding; Golgi apparatus; Golgi membrane; acrosome assembly; cellular response to organic cyclic compound; defense response to bacterium; male gonad development; negative regulation of gene expression; nucleus; positive regulation of cytokine production; regulation of proteasomal protein catabolic process; regulation of transcription, DNA-dependent; sperm motility; spermatid nucleus differentiation; transcription cofactor activity; transcription from RNA polymerase II promoter",PF12329;PF12325;,2.00E-25,CHOYP_LOC580687.1.1,,,,,,,TMF1_HUMAN,Homo sapiens (Human),"acrosome assembly [GO:0001675]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; spermatid nucleus differentiation [GO:0007289]; sperm motility [GO:0030317]; transcription from RNA polymerase II promoter [GO:0006366]" comp120603_c0_seq1,491,43.7882,0.95652571,16,58,,2.00E-30,Q922Z0,D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),GO:0019478; GO:0003884; GO:0008445; GO:0006533; GO:0006531; GO:0048037; GO:0007625; GO:0042445; GO:0007320; GO:0005777,D-amino acid catabolic process; D-amino-acid oxidase activity; D-aspartate oxidase activity; aspartate catabolic process; aspartate metabolic process; cofactor binding; grooming behavior; hormone metabolic process; insemination; peroxisome,PF01266;,,,,,,,,,OXDD_MOUSE,Mus musculus (Mouse),aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; D-amino acid catabolic process [GO:0019478]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insemination [GO:0007320] comp120618_c1_seq1,1004,34.4622,0.55885782,43,31,,5.00E-56,Q5R9K8,ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein),ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein),GO:0005813; GO:0051457; GO:0030496; GO:0005758; GO:0005634; GO:0042517; GO:0005819; GO:0003713,centrosome; maintenance of protein location in nucleus; midbody; mitochondrial intermembrane space; nucleus; positive regulation of tyrosine phosphorylation of Stat3 protein; spindle; transcription coactivator activity,PF11527;,2.00E-68,CHOYP_LOC100367381.2.2,,,,,,,AR2BP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),maintenance of protein location in nucleus [GO:0051457]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517] comp120620_c0_seq3,1833,43.808,0.52955888,84,21,,8.00E-102,Q91YK0,Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79),Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79),GO:0005737; GO:0005874,cytoplasm; microtubule,,9.00E-90,CHOYP_BRAFLDRAFT_67566.4.4,,,,,,,LRC49_MOUSE,Mus musculus (Mouse), comp120622_c0_seq1,622,38.4244,0.91888143,1,80,,2.00E-11,P61315,"Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)","Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)",GO:0032580; GO:0009058; GO:0001733; GO:0016021,Golgi cisterna membrane; biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane,PF06990;,,,,,,,,,G3ST3_MOUSE,Mus musculus (Mouse),glycolipid biosynthetic process [GO:0009247] comp120625_c0_seq1,807,42.5031,0.93499565,23,219,,4.00E-26,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,,,,,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp120634_c0_seq2,1079,42.5394,0.47619089,35,81,,3.00E-88,O54922,Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70),Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70),GO:0005829; GO:0000145; GO:0006887; GO:0005886; GO:0015031,cytosol; exocyst; exocytosis; plasma membrane; protein transport,PF03081;,2.00E-89,CHOYP_LOC574569.1.1,9.00E-28,ruditapes_c17458,,,,,EXOC7_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; protein transport [GO:0015031] comp120635_c0_seq1,913,40.1972,0.65676725,166,1424,,1.00E-57,Q3UFB2,Box C/D snoRNA protein 1 (Zinc finger HIT domain-containing protein 6),Box C/D snoRNA protein 1 (Zinc finger HIT domain-containing protein 6),GO:0000492; GO:0046872; GO:0070761; GO:0042254,box C/D snoRNP assembly; metal ion binding; pre-snoRNP complex; ribosome biogenesis,PF04438;,,,,,,,,,BCD1_MOUSE,Mus musculus (Mouse),box C/D snoRNP assembly [GO:0000492]; protein oligomerization [GO:0051259]; ribosome biogenesis [GO:0042254]; snoRNA localization [GO:0048254] comp120638_c0_seq1,647,46.9861,0.51888553,20,62,,6.00E-49,P53349,Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),GO:0005524; GO:0008545; GO:0004709; GO:0000186; GO:0008637; GO:0005829; GO:0003382; GO:0061029; GO:0030838; GO:0030334; GO:0007179; GO:0042060; GO:0008270,ATP binding; JUN kinase kinase activity; MAP kinase kinase kinase activity; activation of MAPKK activity; apoptotic mitochondrial changes; cytosol; epithelial cell morphogenesis; eyelid development in camera-type eye; positive regulation of actin filament polymerization; regulation of cell migration; transforming growth factor beta receptor signaling pathway; wound healing; zinc ion binding,PF00069;PF04434;,,,,,,,,,M3K1_MOUSE,Mus musculus (Mouse),activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060] comp120644_c0_seq1,398,40.7035,0.48718256,0,5,,6.00E-35,Q90WJ3,PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) (SMAD wing for transcriptional activation) (Protein Swift),PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) (SMAD wing for transcriptional activation) (Protein Swift),GO:0006281; GO:0005634; GO:0006355; GO:0006351,"DNA repair; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00533;PF12738;PF16770;,,,,,,,,,PAXI1_XENLA,Xenopus laevis (African clawed frog),"DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120644_c0_seq2,811,49.1985,0.32733736,33,19,,3.00E-34,Q6NZQ4,PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),GO:0030330; GO:0006310; GO:0006281; GO:0060612; GO:0060717; GO:0043542; GO:0051568; GO:0035097; GO:0016363; GO:0000416; GO:0051571; GO:0035066; GO:0045830; GO:0031398; GO:0060261; GO:0006974; GO:0010212; GO:0006351; GO:0001570,"DNA damage response, signal transduction by p53 class mediator; DNA recombination; DNA repair; adipose tissue development; chorion development; endothelial cell migration; histone H3-K4 methylation; histone methyltransferase complex; nuclear matrix; positive regulation of histone H3-K36 methylation; positive regulation of histone H3-K4 methylation; positive regulation of histone acetylation; positive regulation of isotype switching; positive regulation of protein ubiquitination; positive regulation of transcription initiation from RNA polymerase II promoter; response to DNA damage stimulus; response to ionizing radiation; transcription, DNA-dependent; vasculogenesis",PF00533;PF12738;PF16770;,6.00E-50,CHOYP_PAXI1.3.4,,,,,,,PAXI1_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; cellular response to DNA damage stimulus [GO:0006974]; chorion development [GO:0060717]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K36 methylation [GO:0000416]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]" comp120653_c0_seq1,785,36.1783,0.70514468,0,0,,3.00E-17,Q14585,Zinc finger protein 345 (Zinc finger protein HZF10),Zinc finger protein 345 (Zinc finger protein HZF10),GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006359; GO:0006366; GO:0006383,DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter,PF00096;PF13912;PF13465;,,,,,,,,,ZN345_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366] comp120653_c0_seq3,880,35,0.67691213,2,4,,1.00E-15,Q52M93,Zinc finger protein 585B (zinc finger protein 41-like protein),Zinc finger protein 585B (zinc finger protein 41-like protein),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,Z585B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120655_c0_seq1,295,40.678,0.74331211,4,54,,1.00E-07,Q53H47,Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion gene-containing protein) (HsMar1) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.43); Mariner transposase Hsmar1 (EC 3.1.-.-)],Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion protein) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.43); Transposon Hsmar1 transposase (EC 3.1.-.-)],GO:0000737; GO:0000729; GO:0015074; GO:0005694; GO:0004519; GO:0018024; GO:0071157; GO:2001251; GO:0005634; GO:2001034; GO:0043566; GO:0004803; GO:0006313; GO:0008270,"DNA catabolic process, endonucleolytic; DNA double-strand break processing; DNA integration; chromosome; endonuclease activity; histone-lysine N-methyltransferase activity; negative regulation of cell cycle arrest; negative regulation of chromosome organization; nucleus; positive regulation of double-strand break repair via nonhomologous end joining; structure-specific DNA binding; transposase activity; transposition, DNA-mediated; zinc ion binding",PF05033;PF00856;PF01359;,,,,,,,,,SETMR_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA catabolic process, endonucleolytic [GO:0000737]; DNA double-strand break processing [GO:0000729]; DNA integration [GO:0015074]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; mitotic DNA integrity checkpoint [GO:0044774]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of chromosome organization [GO:2001251]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; replication fork processing [GO:0031297]" comp120661_c0_seq1,538,34.7584,0.4330823,6,14,,4.00E-20,Q5EA75,Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),GO:0004306; GO:0006646,ethanolamine-phosphate cytidylyltransferase activity; phosphatidylethanolamine biosynthetic process,PF01467;,,,,,,,,,PCY2_BOVIN,Bos taurus (Bovine),phosphatidylethanolamine biosynthetic process [GO:0006646] comp120661_c0_seq2,492,32.5203,0.30817443,0,0,,1.00E-06,Q5EA75,Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),GO:0004306; GO:0006646,ethanolamine-phosphate cytidylyltransferase activity; phosphatidylethanolamine biosynthetic process,PF01467;,,,,,,,,,PCY2_BOVIN,Bos taurus (Bovine),phosphatidylethanolamine biosynthetic process [GO:0006646] comp120665_c1_seq1,1430,37.9021,0.46927672,280,1622,,1.00E-94,Q9BUN8,Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1),Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1),GO:0030433; GO:0042288; GO:0005769; GO:0030968; GO:0030176; GO:0019060; GO:0005770; GO:0004872; GO:0030970,"ER-associated protein catabolic process; MHC class I protein binding; early endosome; endoplasmic reticulum unfolded protein response; integral to endoplasmic reticulum membrane; intracellular transport of viral proteins in host cell; late endosome; receptor activity; retrograde protein transport, ER to cytosol",,4.00E-105,CHOYP_LOC100375321.1.1,,,,,,,DERL1_HUMAN,Homo sapiens (Human),"endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; establishment of protein localization [GO:0045184]; intracellular transport of viral protein in host cell [GO:0019060]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]" comp120666_c0_seq1,565,36.4602,0.3401453,10,101,,2.00E-29,Q8VDS8,Syntaxin-18,Syntaxin-18,GO:0000139; GO:0005789; GO:0016021; GO:0006886; GO:0016192,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; intracellular protein transport; vesicle-mediated transport,PF10496;,7.00E-41,CHOYP_STX18.2.2,,,,,,,STX18_MOUSE,Mus musculus (Mouse),"endoplasmic reticulum membrane organization [GO:0090158]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of organelle assembly [GO:1902117]; regulation of Golgi organization [GO:1903358]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp120669_c1_seq2,880,43.75,0.55191551,47,34,,8.00E-20,Q9NQX5,Neural proliferation differentiation and control protein 1 (NPDC-1),Neural proliferation differentiation and control protein 1 (NPDC-1),GO:0016021,integral to membrane,PF06809;,1.00E-77,CHOYP_LOC100898516.1.1,,,,,,,NPDC1_HUMAN,Homo sapiens (Human), comp120681_c0_seq2,768,44.9219,0.41567638,35,8,,4.00E-39,Q9ESF1,Otoferlin (Fer-1-like protein 2),Otoferlin (Fer-1-like protein 2),GO:0016323; GO:0005509; GO:0030054; GO:0005789; GO:0016021; GO:0007605; GO:0016079; GO:0030672,basolateral plasma membrane; calcium ion binding; cell junction; endoplasmic reticulum membrane; integral to membrane; sensory perception of sound; synaptic vesicle exocytosis; synaptic vesicle membrane,PF00168;PF08150;PF08151;PF16165;,4.00E-51,CHOYP_LOC724747.1.1,,,,,,,OTOF_MOUSE,Mus musculus (Mouse),sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] comp120683_c0_seq1,428,42.757,0.36550832,14,30,,,,,,,,,1.00E-49,CHOYP_BRAFLDRAFT_120211.1.1,,,,,,,,, comp120683_c1_seq2,793,45.0189,0.54824015,7,14,,1.00E-44,Q09417,Protein RIC1 homolog,Guanine nucleotide exchange factor subunit R06F6.8 (Protein RIC1 homolog),GO:0016021,integral to membrane,PF07064;,,,,,,,,,RIC1_CAEEL,Caenorhabditis elegans,"negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]" comp120683_c2_seq1,1137,47.0536,0.46479108,42,47,,1.00E-88,Q4ADV7,Protein RIC1 homolog (Connexin-43-interacting protein of 150 kDa),RAB6A-GEF complex partner protein 1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog),GO:0016021,integral to membrane,PF07064;,,,,,,,,,RIC1_HUMAN,Homo sapiens (Human),"negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]" comp120685_c0_seq1,466,34.5494,1.26056471,69,54,,2.00E-06,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp120690_c1_seq1,340,36.4706,0.36431939,4,26,,1.00E-08,Q76EC5,Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2),Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2),GO:0000139; GO:0001537; GO:0016051; GO:0016021; GO:0006790,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; carbohydrate biosynthetic process; integral to membrane; sulfur compound metabolic process,PF03567;,,,,,,,,,CHST9_MOUSE,Mus musculus (Mouse),carbohydrate biosynthetic process [GO:0016051]; sulfur compound metabolic process [GO:0006790] comp120719_c2_seq2,810,39.0123,0.55874452,18,56,,5.00E-19,Q9Z2P6,Synaptosomal-associated protein 29 (SNAP-29) (Golgi SNARE of 32 kDa) (Gs32) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29),Synaptosomal-associated protein 29 (SNAP-29) (Golgi SNARE of 32 kDa) (Gs32) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29),GO:0031201; GO:0000046; GO:0030054; GO:0043005; GO:0015031; GO:0045202,SNARE complex; autophagic vacuole fusion; cell junction; neuron projection; protein transport; synapse,,,,,,,,,,SNP29_RAT,Rattus norvegicus (Rat),autophagosome maturation [GO:0097352]; cilium assembly [GO:0042384]; protein transport [GO:0015031]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] comp120734_c0_seq1,598,39.1304,0.66887703,15,63,,3.00E-13,P14002,Thermostable beta-glucosidase B (EC 3.2.1.21) (Beta-D-glucoside glucohydrolase) (Cellobiase) (Gentiobiase),Thermostable beta-glucosidase B (EC 3.2.1.21) (Beta-D-glucoside glucohydrolase) (Cellobiase) (Gentiobiase),GO:0008422; GO:0030245,beta-glucosidase activity; cellulose catabolic process,PF14310;PF00933;PF01915;,,,,,,,,,BGLB_CLOTH,Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum),cellulose catabolic process [GO:0030245] comp120742_c0_seq2,1087,43.1463,0.56171453,2,17,,9.00E-111,Q6UB28,"Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D)","Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D)",GO:0031365; GO:0004177; GO:0046872; GO:0008235; GO:0005739; GO:0018206; GO:0006508,N-terminal protein amino acid modification; aminopeptidase activity; metal ion binding; metalloexopeptidase activity; mitochondrion; peptidyl-methionine modification; proteolysis,PF00557;,1.00E-16,CHOYP_LOC100083996.1.1,,,,,,,AMP1D_HUMAN,Homo sapiens (Human),N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084] comp120742_c0_seq4,531,44.0678,0.66087191,0,0,,3.00E-06,P33111,Uncharacterized protein in adk 3'region (Fragment),Uncharacterized protein in adk 3'region (Fragment),GO:0009987,cellular process,PF00557;,2.00E-16,CHOYP_TRIADDRAFT_53589.1.1,,,,,,,YADK_MICLU,Micrococcus luteus (Micrococcus lysodeikticus), comp120748_c0_seq1,562,44.8399,0.42881761,16,19,,3.00E-17,Q66HH4,Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein,Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein,GO:0016021; GO:0006986; GO:0007283,integral to membrane; response to unfolded protein; spermatogenesis,PF00240;,,,,,,,,,HERP2_RAT,Rattus norvegicus (Rat),response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283] comp120755_c0_seq1,1087,42.1343,0.33663395,48,82,,,,,,,,,2.00E-19,CHOYP_BRAFLDRAFT_88079.2.2,,,,,,,,, comp120758_c0_seq1,1930,36.7876,0.49485474,570,1940,,2.00E-93,Q6DJM2,"Mitochondrial translocator assembly and maintenance protein 41 homolog (TAM41) (MMP37-like protein, mitochondrial)","Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41)",GO:0031314; GO:0030150,extrinsic to mitochondrial inner membrane; protein import into mitochondrial matrix,PF09139;,1.00E-24,CHOYP_TAM41.1.1,,,,,,,TAM41_XENLA,Xenopus laevis (African clawed frog),cardiolipin biosynthetic process [GO:0032049]; CDP-diacylglycerol biosynthetic process [GO:0016024] comp120760_c0_seq1,515,40,0.34784415,10,49,,1.00E-08,P42906,Putative N-acetylgalactosamine-6-phosphate deacetylase (EC 3.5.1.-),Putative N-acetylgalactosamine-6-phosphate deacetylase (EC 3.5.1.-),GO:0005975; GO:0016787,carbohydrate metabolic process; hydrolase activity,PF01979;,,,,,,,,,AGAA_ECOLI,Escherichia coli (strain K12),adenine catabolic process [GO:0006146]; carbohydrate metabolic process [GO:0005975]; hypoxanthine biosynthetic process [GO:0046101] comp120760_c2_seq1,422,44.3128,0.48620963,0,0,,,,,,,,,3.00E-24,CHOYP_AMDHD2.2.2,,,,,,,,, comp120760_c2_seq2,590,44.4068,0.38320181,4,10,,2.00E-80,Q6P0U0,Putative N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2) (GlcNAc 6-P deacetylase),N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2),GO:0006044; GO:0008448; GO:0019262; GO:0005975; GO:0046872,N-acetylglucosamine metabolic process; N-acetylglucosamine-6-phosphate deacetylase activity; N-acetylneuraminate catabolic process; carbohydrate metabolic process; metal ion binding,PF01979;,,,,,,,,,NAGA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262] comp120766_c0_seq1,1151,43.788,0.43606115,2,0,,1.00E-07,A0JPQ7,Uncharacterized protein C19orf47 homolog,Uncharacterized protein C19orf47 homolog,,,,,,,,,,,,CS047_RAT,Rattus norvegicus (Rat), comp120766_c0_seq2,1138,43.9367,0.43782467,3,0,,3.00E-08,Q8N9M1,Uncharacterized protein C19orf47,Uncharacterized protein C19orf47,,,,2.00E-13,CHOYP_KDM2B.1.1,,,,,,,CS047_HUMAN,Homo sapiens (Human), comp120780_c2_seq1,687,44.2504,0.23262378,7,63,,2.00E-54,Q6DI40,Tetratricopeptide repeat protein 33 (TPR repeat protein 33),Tetratricopeptide repeat protein 33 (TPR repeat protein 33),,,,,,1.00E-23,ruditapes_c29874,,,,,TTC33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp120787_c0_seq1,1463,35.1333,0.46956783,122,1,,9.00E-35,Q4GZT3,Polycystin-2 (Polycystic kidney disease 2 protein homolog),Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2),GO:0007259; GO:0035904; GO:0045180; GO:0009925; GO:0001658; GO:0005262; GO:0005509; GO:0048763; GO:0007050; GO:0005911; GO:0071498; GO:0071464; GO:0071470; GO:0042994; GO:0050982; GO:0003127; GO:0071910; GO:0001892; GO:0031941; GO:0001947; GO:0071458; GO:0071556; GO:0005887; GO:0030027; GO:0016020; GO:0072177; GO:0072284; GO:0072218; GO:0072214; GO:0072219; GO:0072235; GO:0072075; GO:0035502; GO:0072208; GO:0005932; GO:0072686; GO:0031512; GO:2000134; GO:0060315; GO:0021915; GO:0031513; GO:0060674; GO:0002133; GO:0071158; GO:0031659; GO:0031587; GO:0045429; GO:0045944; GO:0005267; GO:0030814; GO:0090279; GO:0042127; GO:0051209; GO:0061441; GO:0061333; GO:0021510; GO:0005245; GO:0005248,"JAK-STAT cascade; aorta development; basal cortex; basal plasma membrane; branching involved in ureteric bud morphogenesis; calcium channel activity; calcium ion binding; calcium-induced calcium release activity; cell cycle arrest; cell-cell junction; cellular response to fluid shear stress; cellular response to hydrostatic pressure; cellular response to osmotic stress; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; detection of nodal flow; determination of liver left/right asymmetry; embryonic placenta development; filamentous actin; heart looping; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; lamellipodium; membrane; mesonephric duct development; metanephric S-shaped body morphogenesis; metanephric ascending thin limb development; metanephric cortex development; metanephric cortical collecting duct development; metanephric distal tubule development; metanephric mesenchyme development; metanephric part of ureteric bud development; metanephric smooth muscle tissue development; microtubule basal body; mitotic spindle; motile primary cilium; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of ryanodine-sensitive calcium-release channel activity; neural tube development; nonmotile primary cilium; placenta blood vessel development; polycystin complex; positive regulation of cell cycle arrest; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of nitric oxide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; potassium channel activity; regulation of cAMP metabolic process; regulation of calcium ion import; regulation of cell proliferation; release of sequestered calcium ion into cytosol; renal artery morphogenesis; renal tubule morphogenesis; spinal cord development; voltage-gated calcium channel activity; voltage-gated sodium channel activity",PF08016;,,,,,,,,,PKD2_BOVIN,Bos taurus (Bovine),"aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]" comp120788_c0_seq1,938,45.8422,0.44705628,35,17,,3.00E-109,P83852,Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) (Fragment),Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) (Fragment),GO:0016021; GO:0004181; GO:0006508; GO:0004185; GO:0008270,integral to membrane; metallocarboxypeptidase activity; proteolysis; serine-type carboxypeptidase activity; zinc ion binding,PF00246;,1.00E-66,CHOYP_LOC100533325.1.1,,,,,,,CBPD_LOPSP,Lophonetta specularioides (Crested duck) (Anas specularioides),proteolysis [GO:0006508] comp120791_c0_seq1,729,35.5281,0.23042973,132,973,,1.00E-15,Q9CXL3,Uncharacterized protein C7orf50 homolog,Uncharacterized protein C7orf50 homolog,,,PF10180;,,,,,,,,,CG050_MOUSE,Mus musculus (Mouse), comp120795_c1_seq1,719,44.6453,0.25572267,26,41,,1.00E-28,Q5U1Z0,Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0030234; GO:0005886; GO:0043547,GTPase activator activity; cytoplasm; enzyme regulator activity; plasma membrane; positive regulation of GTPase activity,PF14656;PF14655;,1.00E-13,CHOYP_RBGPR.1.1,,,,,,,RBGPR_RAT,Rattus norvegicus (Rat),positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp120811_c1_seq1,769,41.4824,0.5792234,21,40,,1.00E-97,Q9NUQ9,Protein FAM49B (L1),Protein FAM49B (L1),GO:0005929,cilium,PF07159;,6.00E-62,CHOYP_FA49B.1.1,,,,,,,FA49B_HUMAN,Homo sapiens (Human), comp120815_c1_seq1,437,40.0458,0.63848731,4,0,,1.00E-40,P54278,Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2),Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2),GO:0005524; GO:0016887; GO:0032389; GO:0004519; GO:0006298; GO:0090305; GO:0007131; GO:0042493; GO:0032138; GO:0016446; GO:0016447,ATP binding; ATPase activity; MutLalpha complex; endonuclease activity; mismatch repair; nucleic acid phosphodiester bond hydrolysis; reciprocal meiotic recombination; response to drug; single base insertion or deletion binding; somatic hypermutation of immunoglobulin genes; somatic recombination of immunoglobulin gene segments,PF01119;PF08676;,,,,,,,,,PMS2_HUMAN,Homo sapiens (Human),mismatch repair [GO:0006298]; response to drug [GO:0042493]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp120815_c1_seq3,346,39.0173,0.87828621,0,0,,4.00E-08,B9DPC0,DNA mismatch repair protein MutL,DNA mismatch repair protein MutL,GO:0005524; GO:0006298; GO:0030983,ATP binding; mismatch repair; mismatched DNA binding,PF01119;PF08676;,1.00E-40,CHOYP_PMS2.1.1,,,,,,,MUTL_STACT,Staphylococcus carnosus (strain TM300),mismatch repair [GO:0006298] comp120817_c0_seq1,765,44.183,0.59928979,48,0,,4.00E-18,Q5G267,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_MACMU,Macaca mulatta (Rhesus macaque),exocytosis [GO:0006887] comp120832_c1_seq1,529,45.1796,0.38129633,0,0,,4.00E-33,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp120832_c1_seq2,981,44.0367,0.34338702,12,3,,6.00E-72,P10079,Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),GO:0032579; GO:0005509; GO:0016023; GO:0005615,apical lamina of hyaline layer; calcium ion binding; cytoplasmic membrane-bounded vesicle; extracellular space,PF01382;PF00431;PF00008;,,,,,,,,,FBP1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp120845_c0_seq1,562,44.8399,0.60286157,1,84,,3.00E-18,Q86GC8,Acetylcholinesterase (AChE) (EC 3.1.1.7),Acetylcholinesterase (AChE) (EC 3.1.1.7),GO:0003990; GO:0004091; GO:0030054; GO:0005576; GO:0042135; GO:0005886; GO:0045202,acetylcholinesterase activity; carboxylesterase activity; cell junction; extracellular region; neurotransmitter catabolic process; plasma membrane; synapse,PF00135;,,,,,,,,,ACES_CULPI,Culex pipiens (House mosquito),neurotransmitter catabolic process [GO:0042135] comp120847_c0_seq1,859,44.4703,0.52142829,17,38,,1.00E-82,Q8BWZ3,"N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)","N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)",GO:0005737,cytoplasm,PF09797;,2.00E-82,CHOYP_NAA25.1.1,,,,,,,NAA25_MOUSE,Mus musculus (Mouse),N-terminal peptidyl-methionine acetylation [GO:0017196] comp120855_c0_seq1,1173,49.4459,0.39403558,66,54,,2.00E-30,O15405,TOX high mobility group box family member 3 (CAG trinucleotide repeat-containing gene F9 protein) (Trinucleotide repeat-containing gene 9 protein),TOX high mobility group box family member 3 (CAG trinucleotide repeat-containing gene F9 protein) (Trinucleotide repeat-containing gene 9 protein),GO:0006915; GO:0003682; GO:0034056; GO:0043524; GO:0005634; GO:0045893; GO:0042803; GO:0006351,"apoptotic process; chromatin binding; estrogen response element binding; negative regulation of neuron apoptotic process; nucleus; positive regulation of transcription, DNA-dependent; protein homodimerization activity; transcription, DNA-dependent",PF00505;,2.00E-46,CHOYP_LOC663375.1.1,,,,,,,TOX3_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp120859_c1_seq1,268,29.8507,1.5038644,5,12,,2.00E-09,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp120863_c1_seq2,396,40.9091,0.36578857,13,27,,2.00E-58,O08586,"Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)","Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)",GO:0030165; GO:0016605; GO:0043220; GO:0007092; GO:0001525; GO:0006915; GO:0060070; GO:0048738; GO:0032286; GO:0021955; GO:0005737; GO:0060997; GO:0021542; GO:0043542; GO:0048853; GO:0046855; GO:0051717; GO:0009898; GO:0007611; GO:0045475; GO:0060291; GO:0000287; GO:0060179; GO:0042711; GO:0033555; GO:0035749; GO:0043066; GO:0050771; GO:0090344; GO:0030336; GO:0045792; GO:0031658; GO:0061002; GO:0050680; GO:0090394; GO:0051895; GO:0031642; GO:0046621; GO:0051898; GO:0090071; GO:2000808; GO:0043005; GO:0007270; GO:0005634; GO:0046856; GO:0016314; GO:0051800; GO:0004438; GO:2001235; GO:0008284; GO:2000463; GO:2000060; GO:0051091; GO:0097107; GO:0060134; GO:0097105; GO:0060736; GO:0043491; GO:0004722; GO:0050821; GO:0004725; GO:0008138; GO:0002902; GO:0033032; GO:0031647; GO:0060024; GO:0035176; GO:0060074,"PDZ domain binding; PML body; Schmidt-Lanterman incisure; activation of mitotic anaphase-promoting complex activity; angiogenesis; apoptotic process; canonical Wnt receptor signaling pathway; cardiac muscle tissue development; central nervous system myelin maintenance; central nervous system neuron axonogenesis; cytoplasm; dendritic spine morphogenesis; dentate gyrus development; endothelial cell migration; forebrain morphogenesis; inositol phosphate dephosphorylation; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; internal side of plasma membrane; learning or memory; locomotor rhythm; long-term synaptic potentiation; magnesium ion binding; male mating behavior; maternal behavior; multicellular organismal response to stress; myelin sheath adaxonal region; negative regulation of apoptotic process; negative regulation of axonogenesis; negative regulation of cell aging; negative regulation of cell migration; negative regulation of cell size; negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; negative regulation of dendritic spine morphogenesis; negative regulation of epithelial cell proliferation; negative regulation of excitatory postsynaptic membrane potential; negative regulation of focal adhesion assembly; negative regulation of myelination; negative regulation of organ growth; negative regulation of protein kinase B signaling cascade; negative regulation of ribosome biogenesis; negative regulation of synaptic vesicle clustering; neuron projection; neuron-neuron synaptic transmission; nucleus; phosphatidylinositol dephosphorylation; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; positive regulation of apoptotic signaling pathway; positive regulation of cell proliferation; positive regulation of excitatory postsynaptic membrane potential; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of sequence-specific DNA binding transcription factor activity; postsynaptic density assembly; prepulse inhibition; presynaptic membrane assembly; prostate gland growth; protein kinase B signaling cascade; protein serine/threonine phosphatase activity; protein stabilization; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of B cell apoptotic process; regulation of myeloid cell apoptotic process; regulation of protein stability; rhythmic synaptic transmission; social behavior; synapse maturation",PF00782;PF10409;,8.00E-32,CHOYP_PTEN.1.1,,,,,,,PTEN_MOUSE,Mus musculus (Mouse),"adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031658]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myelination [GO:0031642]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of synaptic vesicle clustering [GO:2000808]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]" comp120864_c0_seq1,895,41.2291,0.47761254,24,80,,5.00E-40,Q9UJU3,Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228),Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZF112_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp120867_c1_seq1,350,34.5714,0.86596102,0,75,,5.00E-19,Q9DGD1,"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.-) (EC 2.4.1.145) (N-acetylglucosaminyltransferase VI) (GnT-VI) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc)","Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.-) (EC 2.4.1.145) (N-acetylglucosaminyltransferase VI) (GnT-VI) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc)",GO:0000139; GO:0008454; GO:0016021; GO:0046872; GO:0006486,"Golgi membrane; alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; integral to membrane; metal ion binding; protein glycosylation",PF04666;,,,,,,,,,MGT4C_CHICK,Gallus gallus (Chicken),N-glycan processing [GO:0006491] comp120867_c1_seq2,580,38.4483,0.93483786,0,75,,3.00E-26,Q9UQ53,"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)","Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)",GO:0000139; GO:0006491; GO:0008454; GO:0016021; GO:0046872; GO:0043687; GO:0018279,"Golgi membrane; N-glycan processing; alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; integral to membrane; metal ion binding; post-translational protein modification; protein N-linked glycosylation via asparagine",PF04666;,,,,,,,,,MGT4B_HUMAN,Homo sapiens (Human),N-glycan processing [GO:0006491] comp120880_c0_seq1,254,35.4331,0.50596022,0,18,,1.00E-06,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp120880_c3_seq1,358,34.3575,1.13608481,5,21,,3.00E-11,Q00657,Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen),Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen),GO:0001525; GO:0016324; GO:0006954; GO:0005887; GO:0031258; GO:0010977; GO:0048663; GO:0016322; GO:0010226; GO:0004871; GO:0048771,angiogenesis; apical plasma membrane; inflammatory response; integral to plasma membrane; lamellipodium membrane; negative regulation of neuron projection development; neuron fate commitment; neuron remodeling; response to lithium ion; signal transducer activity; tissue remodeling,PF00054;PF02210;,,,,,,,,,CSPG4_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; cell migration [GO:0016477]; inflammatory response [GO:0006954]; negative regulation of neuron projection development [GO:0010977]; neuron remodeling [GO:0016322]; response to lithium ion [GO:0010226]; tissue remodeling [GO:0048771] comp120885_c0_seq1,764,37.8272,1.1764726,1,163,,,,,,,,,1.00E-13,CHOYP_PHUM_PHUM377430.2.2,2.00E-22,ruditapes_c9162,,,,,,, comp120887_c0_seq2,1587,48.1411,0.2949887,6,18,,,,,,,,,2.00E-34,CHOYP_LOC100374968.1.1,,,,,,,,, comp120887_c0_seq3,1446,46.5422,0.31999131,0,0,,1.00E-67,Q3TCX3,UPF0469 protein KIAA0907,UPF0469 protein KIAA0907,GO:0003723,RNA binding,,2.00E-34,CHOYP_LOC100374968.1.1,,,,,,,K0907_MOUSE,Mus musculus (Mouse), comp120892_c0_seq3,801,40.1998,0.31768717,12,20,,1.00E-32,Q8IV42,L-seryl-tRNA(Sec) kinase (EC 2.7.1.164) (O-phosphoseryl-tRNA(Sec) kinase),L-seryl-tRNA(Sec) kinase (EC 2.7.1.164) (O-phosphoseryl-tRNA(Sec) kinase),GO:0005524; GO:0016301; GO:0005739; GO:0001514; GO:0097056; GO:0000049,ATP binding; kinase activity; mitochondrion; selenocysteine incorporation; selenocysteinyl-tRNA(Sec) biosynthetic process; tRNA binding,PF08433;,,,,,,,,,PSTK_HUMAN,Homo sapiens (Human),selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056] comp120903_c0_seq1,252,44.4444,0.5214785,5,0,,3.00E-07,Q6CXX3,Protein HIR1,Protein HIR1,GO:0003682; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07569;PF09453;PF00400;,,,,,,,,,HIR1_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp120903_c1_seq1,619,41.8417,0.29736289,30,32,,2.00E-36,Q6ZMY6,WD repeat-containing protein 88 (PQQ repeat and WD repeat-containing protein),WD repeat-containing protein 88 (PQQ repeat and WD repeat-containing protein),,,PF01011;PF00400;,8.00E-15,CHOYP_BRAFLDRAFT_126756.1.1,,,,,,,WDR88_HUMAN,Homo sapiens (Human), comp120908_c0_seq3,694,44.5245,0.29998336,18,16,,4.00E-71,Q2M389,WASH complex subunit 7,WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP),GO:0071203; GO:0016197; GO:0005768,WASH complex; endosomal transport; endosome,PF14746;PF14744;PF14745;,3.00E-77,CHOYP_BRAFLDRAFT_221115.1.1,,,,,,,WASH7_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031] comp120917_c0_seq1,335,44.4776,0.54545941,10,2,,7.00E-09,Q01767,L-lysine-epsilon aminotransferase (L-lysine aminotransferase) (EC 2.6.1.36) (Lysine 6-aminotransferase),L-lysine-epsilon aminotransferase (L-lysine aminotransferase) (EC 2.6.1.36) (Lysine 6-aminotransferase),GO:0045484; GO:0017000; GO:0030170,L-lysine 6-transaminase activity; antibiotic biosynthetic process; pyridoxal phosphate binding,PF00202;,,,,,,,,,LAT_STRC2,Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602),antibiotic biosynthetic process [GO:0017000] comp120917_c1_seq1,307,45.9283,0.37730086,0,14,,2.00E-40,P61922,"4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)","4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)",GO:0047298; GO:0003867; GO:0032144; GO:0048148; GO:0007620; GO:0009448; GO:0007626; GO:0005759; GO:0005739; GO:0045776; GO:0043005; GO:0042135; GO:0042803; GO:0030170; GO:0042493; GO:0045471; GO:0001666; GO:0010039; GO:0035094; GO:0032145,(S)-3-amino-2-methylpropionate transaminase activity; 4-aminobutyrate transaminase activity; 4-aminobutyrate transaminase complex; behavioral response to cocaine; copulation; gamma-aminobutyric acid metabolic process; locomotory behavior; mitochondrial matrix; mitochondrion; negative regulation of blood pressure; neuron projection; neurotransmitter catabolic process; protein homodimerization activity; pyridoxal phosphate binding; response to drug; response to ethanol; response to hypoxia; response to iron ion; response to nicotine; succinate-semialdehyde dehydrogenase binding,PF00202;,3.00E-29,CHOYP_LOC656992.3.3,,,,,,,GABT_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; behavioral response to cocaine [GO:0048148]; cerebellum development [GO:0021549]; copulation [GO:0007620]; exploration behavior [GO:0035640]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; gamma-aminobutyric acid catabolic process [GO:0009450]; locomotory behavior [GO:0007626]; negative regulation of blood pressure [GO:0045776]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of platelet aggregation [GO:0090331]; neurotransmitter catabolic process [GO:0042135]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of dopamine metabolic process [GO:0045964]; positive regulation of heat generation [GO:0031652]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of uterine smooth muscle contraction [GO:0070474]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to nicotine [GO:0035094] comp120926_c0_seq1,698,43.6963,0.72705359,18,0,,7.00E-06,Q14112,Nidogen-2 (NID-2) (Osteonidogen),Nidogen-2 (NID-2) (Osteonidogen),GO:0005604; GO:0005509; GO:0007155; GO:0009986; GO:0007160; GO:0005518,basement membrane; calcium ion binding; cell adhesion; cell surface; cell-matrix adhesion; collagen binding,PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID2_HUMAN,Homo sapiens (Human),basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198] comp120926_c0_seq3,395,43.7975,0.71085791,1,0,,1.00E-06,B5DFC9,Nidogen-2 (NID-2),Nidogen-2 (NID-2),GO:0005604; GO:0005509; GO:0009986; GO:0007160,basement membrane; calcium ion binding; cell surface; cell-matrix adhesion,PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID2_RAT,Rattus norvegicus (Rat),cell-matrix adhesion [GO:0007160] comp120929_c0_seq1,450,36.4444,0.20134028,18,22,,1.00E-08,Q9JIT1,RING finger protein 32 (Limb region protein 2),RING finger protein 32 (Limb region protein 2),GO:0016235; GO:0005768; GO:0008270,aggresome; endosome; zinc ion binding,PF00612;PF13639;PF13445;,,,,,,,,,RNF32_MOUSE,Mus musculus (Mouse), comp120935_c0_seq1,1078,42.9499,0.48338726,32,67,,7.00E-78,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,4.00E-28,CHOYP_UBR3.1.1,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp120942_c1_seq1,613,42.2512,0.76178863,18,18,,1.00E-55,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,3.00E-46,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp120948_c1_seq1,203,39.4089,0.5112906,1,7,,2.00E-21,Q5ZKB8,Cysteine-rich DPF motif domain-containing protein 1,Cysteine-rich DPF motif domain-containing protein 1,,,PF10170;,,,,,,,,,CDPF1_CHICK,Gallus gallus (Chicken), comp120954_c0_seq1,1924,45.9459,1.0545086,82,20,,3.00E-69,O54834,Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1),Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1),GO:0005100; GO:0015629; GO:0007015; GO:0007202; GO:0005737; GO:0048041; GO:0051895; GO:0051497; GO:0016004; GO:0007165,Rho GTPase activator activity; actin cytoskeleton; actin filament organization; activation of phospholipase C activity; cytoplasm; focal adhesion assembly; negative regulation of focal adhesion assembly; negative regulation of stress fiber assembly; phospholipase activator activity; signal transduction,PF00620;,1.00E-43,CHOYP_LOC100366924.1.1,,,,,,,RHG06_MOUSE,Mus musculus (Mouse),actin filament organization [GO:0007015]; activation of phospholipase C activity [GO:0007202]; focal adhesion assembly [GO:0048041]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phospholipase activity [GO:0010518]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] comp120954_c0_seq2,713,45.8626,0.85566793,0,0,,2.00E-07,O57414,Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) (Fragment),Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) (Fragment),GO:0005096; GO:0005737; GO:0043547,GTPase activator activity; cytoplasm; positive regulation of GTPase activity,,,,,,,,,,RHG06_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),actin filament organization [GO:0007015] comp120957_c0_seq1,1266,43.3649,0.59516478,51,14,,4.00E-38,Q5G269,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_PONPY,Pongo pygmaeus (Bornean orangutan),exocytosis [GO:0006887] comp120966_c1_seq1,516,39.7287,1.29574421,5,53,,3.00E-46,Q9EPW2,Krueppel-like factor 15 (Cardiovascular Krueppel-like factor),Krueppel-like factor 15 (Cardiovascular Krueppel-like factor),GO:0014898; GO:0010001; GO:0072112; GO:0015758; GO:0046872; GO:2000757; GO:0005730; GO:0005634; GO:0045944; GO:0045893; GO:0003700; GO:0044212; GO:0006351,"cardiac muscle hypertrophy in response to stress; glial cell differentiation; glomerular visceral epithelial cell differentiation; glucose transport; metal ion binding; negative regulation of peptidyl-lysine acetylation; nucleolus; nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00096;,7.00E-53,CHOYP_KLF15.1.1,,,,,,,KLF15_MOUSE,Mus musculus (Mouse),"cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to peptide [GO:1901653]; glial cell differentiation [GO:0010001]; glomerular visceral epithelial cell differentiation [GO:0072112]; glucose transport [GO:0015758]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; transcription, DNA-templated [GO:0006351]" comp120982_c0_seq1,1266,35.0711,0.31939183,87,396,,1.00E-48,O89016,ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69),ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69),GO:0005524; GO:0006200; GO:0042626; GO:0009235; GO:0005789; GO:0016021,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; cobalamin metabolic process; endoplasmic reticulum membrane; integral to membrane",PF06472;PF00005;,1.00E-17,CHOYP_ABCD4.1.2,,,,,,,ABCD4_MOUSE,Mus musculus (Mouse),cobalamin metabolic process [GO:0009235] comp120991_c2_seq1,374,44.385,0.97997216,3,26,,3.00E-35,Q17766,Folate transporter 1,Folate transporter 1,GO:0005542; GO:0016021; GO:0006810,folic acid binding; integral to membrane; transport,PF01770;,,,,,,,,,FOLT1_CAEEL,Caenorhabditis elegans,transmembrane transport [GO:0055085] comp120996_c3_seq2,814,39.8034,0.3422414,40,76,,1.00E-24,Q864U1,Breast cancer type 1 susceptibility protein homolog (EC 6.3.2.-),Breast cancer type 1 susceptibility protein homolog (EC 6.3.2.-),GO:0031436; GO:0003677; GO:0006310; GO:0006281; GO:0007049; GO:0005694; GO:0006633; GO:0045717; GO:0085020; GO:0051865; GO:0004842; GO:0008270,BRCA1-BARD1 complex; DNA binding; DNA recombination; DNA repair; cell cycle; chromosome; fatty acid biosynthetic process; negative regulation of fatty acid biosynthetic process; protein K6-linked ubiquitination; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00533;PF12820;PF00097;,,,,,,,,,BRCA1_BOVIN,Bos taurus (Bovine),"cell cycle [GO:0007049]; chordate embryonic development [GO:0043009]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair via homologous recombination [GO:0000724]; fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of histone acetylation [GO:0035067]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; transcription, DNA-templated [GO:0006351]" comp121010_c0_seq1,724,36.7403,0.70573886,46,836,,2.00E-24,Q53533,Streptavidin-V2 (SA V2),Streptavidin-V2 (SA V2),GO:0005576,extracellular region,PF01382;,,,,,,,,,SAV2_STRVL,Streptomyces violaceus (Streptomyces venezuelae), comp121012_c1_seq1,648,47.2222,0.41990266,24,29,,6.00E-60,Q5XTS1,Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Group VIB calcium-independent phospholipase A2) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8),Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Group VIB calcium-independent phospholipase A2) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8),GO:0000139; GO:0005789; GO:0016021; GO:0016042; GO:0004622; GO:0048471,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; lipid catabolic process; lysophospholipase activity; perinuclear region of cytoplasm,PF01734;,,,,,,,,,PLPL8_RABIT,Oryctolagus cuniculus (Rabbit),lipid catabolic process [GO:0016042] comp121014_c0_seq1,669,40.6577,1.01779741,0,0,,4.00E-09,Q54Q53,Probable cytochrome P450 519B1 (EC 1.14.-.-),Probable cytochrome P450 519B1 (EC 1.14.-.-),GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705,"heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C519B_DICDI,Dictyostelium discoideum (Slime mold), comp121014_c0_seq2,899,42.0467,1.05867657,3,30,,3.00E-65,Q9CX98,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_MOUSE,Mus musculus (Mouse), comp121017_c0_seq1,409,44.7433,0.63985977,19,15,,1.00E-51,Q5REB1,Metallophosphoesterase MPPED2 (EC 3.1.-.-) (Metallophosphoesterase domain-containing protein 2),Metallophosphoesterase MPPED2 (EC 3.1.-.-) (Metallophosphoesterase domain-containing protein 2),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF00149;,6.00E-21,CHOYP_MPPD2.2.3,,,,,,,MPPD2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp121018_c0_seq2,423,50.591,0.51847613,5,12,,5.00E-20,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp121024_c0_seq1,1423,46.3106,0.55016989,33,4,,2.00E-164,Q5XF89,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,1.00E-35,CHOYP_LOC660831.1.1,,,,,,,AT133_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp121024_c0_seq2,1043,43.3365,0.52507743,3,0,,1.00E-102,Q5XF89,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,3.00E-87,CHOYP_LOC582670.1.1,,,,,,,AT133_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp121024_c0_seq3,945,41.7989,0.44794073,3,3,,,,,,,,,7.00E-75,CHOYP_LOC582670.1.1,,,,,,,,, comp121029_c1_seq2,673,45.9138,0.31232692,14,9,,2.00E-63,Q8BQM9,Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09497;PF12145;PF12144;,1.00E-13,CHOYP_MD12L.1.1,,,,,,,MD12L_MOUSE,Mus musculus (Mouse), comp121043_c1_seq2,525,41.3333,0.64224897,4,4,,6.00E-27,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp121051_c0_seq1,1030,46.7961,1.06817341,82,77,,3.00E-27,Q62633,"Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)","Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)",GO:0016324; GO:0008206; GO:0008508; GO:0016021; GO:0005634; GO:0000502,apical plasma membrane; bile acid metabolic process; bile acid:sodium symporter activity; integral to membrane; nucleus; proteasome complex,PF01758;,,,,,,,,,NTCP2_RAT,Rattus norvegicus (Rat),bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; sodium ion transport [GO:0006814] comp121052_c0_seq1,1030,39.8058,0.37355108,0,2,,2.00E-49,Q3SX24,F-box only protein 6 (F-box protein that recognizes sugar chains 2),F-box only protein 6 (F-box protein that recognizes sugar chains 2),GO:0006281; GO:0030433; GO:0019005; GO:0031146; GO:0005737; GO:0001948; GO:0016567; GO:0006986,DNA repair; ER-associated protein catabolic process; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cytoplasm; glycoprotein binding; protein ubiquitination; response to unfolded protein,PF12937;PF04300;,,,,,,,,,FBX6_BOVIN,Bos taurus (Bovine),DNA repair [GO:0006281]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; response to unfolded protein [GO:0006986]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp121052_c0_seq2,758,40.6332,0.41951604,2,0,,7.00E-32,Q8NI29,F-box only protein 27 (F-box/G-domain protein 5),F-box only protein 27 (F-box/G-domain protein 5),GO:0019005; GO:0001948; GO:0030163,SCF ubiquitin ligase complex; glycoprotein binding; protein catabolic process,PF00646;PF04300;,,,,,,,,,FBX27_HUMAN,Homo sapiens (Human), comp121058_c0_seq1,613,40.4568,0.40608574,14,33,,2.00E-14,Q3SYK4,Vertnin,Vertnin,,,,,,,,,,,,VRTN_MOUSE,Mus musculus (Mouse), comp121058_c1_seq1,916,40.8297,0.4509537,22,0,,,,,,,,,1.00E-14,CHOYP_LOC100887903.1.2,,,,,,,,, comp121058_c1_seq2,507,41.4201,0.46228226,0,0,,,,,,,,,7.00E-15,CHOYP_LOC100887903.1.2,,,,,,,,, comp121059_c1_seq1,532,43.2331,0.58370044,16,25,,5.00E-13,Q1PSW8,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:2000637; GO:0051865; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,,,,,,,,,LIN41_MOUSE,Mus musculus (Mouse),3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] comp121059_c1_seq2,456,42.3246,0.51638666,0,7,,4.00E-07,Q9U489,Protein lin-41 (Abnormal cell lineage protein 41),Protein lin-41 (Abnormal cell lineage protein 41),GO:0005737; GO:0009957; GO:0007276; GO:0044268; GO:0042787; GO:0040034; GO:0045604; GO:0045138; GO:0004842; GO:0008270,"cytoplasm; epidermal cell fate specification; gamete generation; multicellular organismal protein metabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of development, heterochronic; regulation of epidermal cell differentiation; tail tip morphogenesis; ubiquitin-protein ligase activity; zinc ion binding",PF00630;PF01436;,,,,,,,,,LIN41_CAEEL,Caenorhabditis elegans,"epidermal cell fate specification [GO:0009957]; gamete generation [GO:0007276]; multicellular organismal protein metabolic process [GO:0044268]; nematode male tail tip morphogenesis [GO:0045138]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of development, heterochronic [GO:0040034]; regulation of epidermal cell differentiation [GO:0045604]" comp121059_c2_seq1,1069,42.5631,0.80628404,18,68,,9.00E-18,A4IF63,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,9.00E-100,CHOYP_LOC100645486.1.1,,,,,,,TRIM2_BOVIN,Bos taurus (Bovine),regulation of neuron apoptotic process [GO:0043523] comp121067_c0_seq1,297,41.4141,0.85731697,0,8,,2.00E-14,B3H615,PHD finger protein ING2 (Protein INHIBITOR OF GROWTH 2) (Protein AtING2),PHD finger protein ING2 (Protein INHIBITOR OF GROWTH 2) (Protein AtING2),GO:0016568; GO:0035064; GO:0005634; GO:0040008; GO:0006355; GO:0006351; GO:0008270,"chromatin modification; methylated histone residue binding; nucleus; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF12998;,,,,,,,,,ING2_ARATH,Arabidopsis thaliana (Mouse-ear cress),"chromatin modification [GO:0016568]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121067_c0_seq2,232,42.2414,1.02194881,0,4,,2.00E-29,Q9QXV3,Inhibitor of growth protein 1,Inhibitor of growth protein 1,GO:0007049; GO:0005634; GO:0045893; GO:0006606; GO:0010941; GO:0008270,"cell cycle; nucleus; positive regulation of transcription, DNA-dependent; protein import into nucleus; regulation of cell death; zinc ion binding",PF12998;,2.00E-17,CHOYP_STK11.1.1,,,,,,,ING1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; chromatin modification [GO:0016568]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription, DNA-templated [GO:0045893]; protein import into nucleus [GO:0006606]; regulation of cell death [GO:0010941]" comp121067_c1_seq1,766,43.9948,0.707616,14,101,,,,,,,,,5.00E-31,CHOYP_ISCW_ISCW007158.2.2,,,,,,,,, comp121081_c0_seq1,634,44.0063,0.8395938,15,83,,6.00E-81,Q26614,Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1),Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1),GO:0005524; GO:0016021; GO:0018108; GO:0004714,ATP binding; integral to membrane; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity,PF00041;PF07679;PF07714;,,,,,,,,,FGFR_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp121081_c2_seq1,967,40.6412,0.53067461,20,118,,1.00E-32,P35918,Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase NYK) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309),Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase NYK) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309),GO:0005524; GO:0060837; GO:0048754; GO:0055074; GO:0035584; GO:0045165; GO:0030054; GO:0048469; GO:0002042; GO:0016023; GO:0005769; GO:0035162; GO:0003157; GO:0009897; GO:0005576; GO:0005887; GO:0048286; GO:0001945; GO:2000352; GO:0005634; GO:0001541; GO:0038083; GO:0030513; GO:0070374; GO:0045766; GO:0010595; GO:0001938; GO:0002053; GO:0051770; GO:0014068; GO:0001934; GO:0030949; GO:2001214; GO:0043129; GO:0048010; GO:0005021; GO:0001570,ATP binding; blood vessel endothelial cell differentiation; branching morphogenesis of an epithelial tube; calcium ion homeostasis; calcium-mediated signaling using intracellular calcium source; cell fate commitment; cell junction; cell maturation; cell migration involved in sprouting angiogenesis; cytoplasmic membrane-bounded vesicle; early endosome; embryonic hemopoiesis; endocardium development; external side of plasma membrane; extracellular region; integral to plasma membrane; lung alveolus development; lymph vessel development; negative regulation of endothelial cell apoptotic process; nucleus; ovarian follicle development; peptidyl-tyrosine autophosphorylation; positive regulation of BMP signaling pathway; positive regulation of ERK1 and ERK2 cascade; positive regulation of angiogenesis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of protein phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of vasculogenesis; surfactant homeostasis; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor-activated receptor activity; vasculogenesis,PF07679;PF07714;,2.00E-31,CHOYP_FGFR2.3.3,,,,,,,VGFR2_MOUSE,Mus musculus (Mouse),blood vessel endothelial cell differentiation [GO:0060837]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endocardium development [GO:0003157]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; hemopoiesis [GO:0030097]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymph vessel development [GO:0001945]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vasculogenesis [GO:2001214]; post-embryonic camera-type eye morphogenesis [GO:0048597]; protein autophosphorylation [GO:0046777]; regulation of bone development [GO:1903010]; regulation of cell shape [GO:0008360]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell proliferation [GO:0001936]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; surfactant homeostasis [GO:0043129]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570] comp121082_c0_seq2,865,43.3526,0.27989695,3,11,,1.00E-122,Q5M9F5,Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog),Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog),GO:0005524; GO:0017178; GO:0017183,ATP binding; diphthine-ammonia ligase activity; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01902;,1.00E-83,CHOYP_LOC100744165.1.1,,,,,,,ATBD4_RAT,Rattus norvegicus (Rat),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp121090_c0_seq1,859,39.9302,0.75998689,43,31,,4.00E-41,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,4.00E-27,CHOYP_LOC100892528.1.1,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp121095_c1_seq1,1144,44.2308,1.03947613,0,0,,3.00E-41,Q1JQE6,Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1),Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1),GO:0004091; GO:0005783; GO:0016021; GO:0016042; GO:0042301; GO:0006470; GO:0017171; GO:0006805,carboxylesterase activity; endoplasmic reticulum; integral to membrane; lipid catabolic process; phosphate ion binding; protein dephosphorylation; serine hydrolase activity; xenobiotic metabolic process,PF07859;,,,,,,,,,NCEH1_BOVIN,Bos taurus (Bovine),catabolic process [GO:0009056]; lipid catabolic process [GO:0016042]; protein dephosphorylation [GO:0006470]; SMAD protein signal transduction [GO:0060395]; xenobiotic metabolic process [GO:0006805] comp121095_c1_seq5,1243,43.2019,1.03836911,0,0,,6.00E-48,Q0P5B7,Arylacetamide deacetylase (EC 3.1.1.3),Arylacetamide deacetylase (EC 3.1.1.3),GO:0004091; GO:0005789; GO:0016021; GO:0004806,carboxylesterase activity; endoplasmic reticulum membrane; integral to membrane; triglyceride lipase activity,PF07859;,,,,,,,,,AAAD_BOVIN,Bos taurus (Bovine),metabolic process [GO:0008152]; positive regulation of triglyceride catabolic process [GO:0010898] comp121101_c0_seq1,605,40.1653,0.37021551,18,83,,1.00E-16,O15031,Plexin-B2 (MM1),Plexin-B2 (MM1),GO:0005096; GO:0007420; GO:0005887; GO:0005622; GO:0001843; GO:0007405; GO:0043547; GO:0050772; GO:0032319; GO:0008360; GO:2001222; GO:0001932; GO:0017154,GTPase activator activity; brain development; integral to plasma membrane; intracellular; neural tube closure; neuroblast proliferation; positive regulation of GTPase activity; positive regulation of axonogenesis; regulation of Rho GTPase activity; regulation of cell shape; regulation of neuron migration; regulation of protein phosphorylation; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB2_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp121102_c1_seq1,601,46.4226,0.356214,0,0,,1.00E-34,Q8BG30,Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2),Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2),GO:0032021; GO:0003682; GO:0034244; GO:0006351,"NELF complex; chromatin binding; negative regulation of transcription elongation from RNA polymerase II promoter; transcription, DNA-dependent",,8.00E-34,CHOYP_LOC100117054.1.1,,,,,,,NELFA_MOUSE,Mus musculus (Mouse),"negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp121104_c0_seq1,587,38.1601,0.431825,6,101,,3.00E-17,P02640,Villin-1,Villin-1,GO:0051015; GO:0032432; GO:0051693; GO:0030042; GO:0030041; GO:0051014; GO:0005509; GO:0071364; GO:0035729; GO:0043027; GO:0005737; GO:0060327; GO:0007173; GO:0032433; GO:0030027; GO:0035727; GO:0005902; GO:0005546; GO:0032233; GO:0010634; GO:0042803; GO:0051125; GO:0008360; GO:2000392; GO:0061041; GO:0009617; GO:0001726,"actin filament binding; actin filament bundle; actin filament capping; actin filament depolymerization; actin filament polymerization; actin filament severing; calcium ion binding; cellular response to epidermal growth factor stimulus; cellular response to hepatocyte growth factor stimulus; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; cytoplasmic actin-based contraction involved in cell motility; epidermal growth factor receptor signaling pathway; filopodium tip; lamellipodium; lysophosphatidic acid binding; microvillus; phosphatidylinositol-4,5-bisphosphate binding; positive regulation of actin filament bundle assembly; positive regulation of epithelial cell migration; protein homodimerization activity; regulation of actin nucleation; regulation of cell shape; regulation of lamellipodium morphogenesis; regulation of wound healing; response to bacterium; ruffle",PF00626;PF02209;,,,,,,,,,VILI_CHICK,Gallus gallus (Chicken),actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617] comp121106_c0_seq1,1378,40.8563,0.49341399,33,4,,6.00E-126,Q7ZYC4,Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2),Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2),GO:0005524; GO:0005737; GO:0001676; GO:0004467,ATP binding; cytoplasm; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;,,,,,,,,,ACBG2_XENLA,Xenopus laevis (African clawed frog), comp121106_c0_seq2,961,44.3288,0.446767,0,0,,1.00E-18,Q72YK9,2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase),2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (o-succinylbenzoyl-CoA synthetase) (OSB-CoA synthetase),GO:0005524; GO:0009234; GO:0008756,ATP binding; menaquinone biosynthetic process; o-succinylbenzoate-CoA ligase activity,PF00501;PF13193;,9.00E-55,CHOYP_LOC100372454.1.1,,,,,,,MENE_BACC1,Bacillus cereus (strain ATCC 10987 / NRS 248),menaquinone biosynthetic process [GO:0009234] comp121127_c2_seq1,645,39.6899,0.35540155,26,15,,7.00E-16,Q9JMJ2,F-box/WD repeat-containing protein 4 (F-box and WD-40 domain-containing protein 4) (Protein hagoromo),F-box/WD repeat-containing protein 4 (F-box and WD-40 domain-containing protein 4) (Protein hagoromo),GO:0016055; GO:0051216; GO:0042733; GO:0002053,Wnt receptor signaling pathway; cartilage development; embryonic digit morphogenesis; positive regulation of mesenchymal cell proliferation,PF12937;PF00400;,,,,,,,,,FBXW4_MOUSE,Mus musculus (Mouse),cartilage development [GO:0051216]; embryonic digit morphogenesis [GO:0042733]; limb development [GO:0060173]; positive regulation of mesenchymal cell proliferation [GO:0002053]; Wnt signaling pathway [GO:0016055] comp121136_c0_seq1,670,40.1493,0.93101551,36,113,,5.00E-65,Q5PPV4,Cation transport regulator-like protein 2,Putative glutathione-specific gamma-glutamylcyclotransferase 2 (Gamma-GCG 2) (EC 2.3.2.-) (Cation transport regulator-like protein 2),,,PF04752;,2.00E-22,CHOYP_CHAC2.1.1,5.00E-60,ruditapes_c11956,,,,,CHAC2_XENLA,Xenopus laevis (African clawed frog), comp121163_c0_seq1,958,29.0188,0.59574533,41,84,,5.00E-20,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,2.00E-13,CHOYP_LOC100892427.2.2,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp121165_c0_seq1,692,40.3179,0.65009517,13,66,,9.00E-13,P41696,Asparagine-rich zinc finger protein AZF1,Asparagine-rich zinc finger protein AZF1,GO:0000978; GO:0001077; GO:0071322; GO:0005829; GO:0046872; GO:0005634; GO:0060237,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to carbohydrate stimulus; cytosol; metal ion binding; nucleus; regulation of fungal-type cell wall organization,PF13912;,,,,,,,,,AZF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp121168_c0_seq1,750,39.3333,0.52605865,26,47,,2.00E-14,D7REX8,Protein unc-45 homolog B (Unc-45B),Protein unc-45 homolog B (Unc-45B),GO:0030154; GO:0005829; GO:0007517,cell differentiation; cytosol; muscle organ development,PF11701;,,,,,,,,,UN45B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cardiac muscle tissue development [GO:0048738]; lens development in camera-type eye [GO:0002088]; muscle fiber development [GO:0048747]; myofibril assembly [GO:0030239]; skeletal muscle tissue development [GO:0007519] comp121169_c1_seq2,640,43.125,0.4040987,27,9,,5.00E-74,Q8N9R8,Protein SCAI (Suppressor of cancer cell invasion protein),Protein SCAI (Suppressor of cancer cell invasion protein),GO:0005737; GO:0016021; GO:0035024; GO:0030336; GO:0005634; GO:0006355; GO:0003714; GO:0006351,"cytoplasm; integral to membrane; negative regulation of Rho protein signal transduction; negative regulation of cell migration; nucleus; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF12070;,5.00E-81,CHOYP_ISCW_ISCW022658.2.2,,,,,,,SCAI_HUMAN,Homo sapiens (Human),"negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121169_c1_seq3,291,40.8935,0.16839876,3,0,,,,,,,,,5.00E-33,CHOYP_ISCW_ISCW022658.2.2,,,,,,,,, comp121176_c0_seq1,1115,40.9865,0.45067534,53,61,,6.00E-11,Q02058,Actinorhodin polyketide dimerase (EC 1.-.-.-) (actI ORF6),Actinorhodin polyketide dimerase (EC 1.-.-.-) (actI ORF6),GO:0010181; GO:0017000; GO:0042602,FMN binding; antibiotic biosynthetic process; riboflavin reductase (NADPH) activity,PF01613;,3.00E-30,CHOYP_BRAFLDRAFT_118645.1.1,,,,,,,DIM6_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),antibiotic biosynthetic process [GO:0017000] comp121202_c0_seq1,626,46.4856,0.39067393,33,16,,8.00E-15,Q5HZQ9,Pecanex-like protein 4,Pecanex-like protein 4 (Pecanex homolog protein 4),GO:0016021,integral to membrane,PF05041;,,,,,,,,,PCX4_XENLA,Xenopus laevis (African clawed frog), comp121202_c1_seq1,385,45.4545,0.45447716,11,0,,3.00E-19,Q63HM2,Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2),Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2) (Pecanex homolog protein 4),GO:0016021,integral to membrane,PF05041;,,,,,,,,,PCX4_HUMAN,Homo sapiens (Human), comp121206_c0_seq1,661,39.0318,0.36978734,39,64,,3.00E-88,B3DH20,Protein tilB homolog (Leucine-rich repeat-containing 6-like protein) (Leucine-rich repeat-containing protein 6) (Seahorse),Protein tilB homolog (Leucine-rich repeat-containing 6-like protein) (Leucine-rich repeat-containing protein 6) (Seahorse),GO:0005929; GO:0005737,cilium; cytoplasm,,6.00E-55,CHOYP_LOC586953.1.1,2.00E-58,ruditapes_c23410,,,,,TILB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; convergent extension involved in gastrulation [GO:0060027]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; epithelial cilium movement [GO:0003351]; heart jogging [GO:0003146]; heart looping [GO:0001947]; motile cilium assembly [GO:0044458]; pronephros development [GO:0048793] comp121207_c0_seq1,452,42.9204,0.38516503,7,22,,5.00E-43,Q66H54,FTS and Hook-interacting protein (FHIP) (Protein FAM160A2),FTS and Hook-interacting protein (FHIP) (Protein FAM160A2),GO:0070695; GO:0045022; GO:0007032; GO:0008333; GO:0007040; GO:0015031,FHF complex; early endosome to late endosome transport; endosome organization; endosome to lysosome transport; lysosome organization; protein transport,PF10257;,,,,,,,,,F16A2_RAT,Rattus norvegicus (Rat),early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; protein transport [GO:0015031] comp121207_c2_seq1,548,45.2555,0.67998923,8,49,,6.00E-36,A7S6A1,UPF0518 protein v1g243165,UPF0518 protein v1g243165,,,PF10257;,3.00E-45,CHOYP_F16A2.3.3,,,,,,,U518_NEMVE,Nematostella vectensis (Starlet sea anemone), comp121208_c0_seq2,499,32.6653,0.99510504,8,0,,6.00E-15,Q7LHG5,Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,,,,,,,,,YI31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp121225_c0_seq1,461,45.1193,0.51644398,15,59,,1.00E-77,P09215,Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)],Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)],GO:0005524; GO:0007568; GO:0006915; GO:0015810; GO:0004699; GO:0007049; GO:0042149; GO:0032869; GO:0090398; GO:0032963; GO:0005829; GO:0042742; GO:0005783; GO:0008047; GO:0035556; GO:0046872; GO:0005739; GO:0043407; GO:0030837; GO:0051490; GO:0034351; GO:0046627; GO:0050732; GO:0090331; GO:0042119; GO:0005634; GO:0018107; GO:0048471; GO:0005886; GO:0043406; GO:0043065; GO:2000304; GO:0046326; GO:2000753; GO:1900163; GO:0035307; GO:2001022; GO:2000755; GO:0032930; GO:0046777; GO:0043200; GO:0042493; GO:0045471; GO:0009749; GO:0009408; GO:0042542; GO:0001666; GO:0009612; GO:0014070; GO:0023021,ATP binding; aging; apoptotic process; aspartate transport; calcium-independent protein kinase C activity; cell cycle; cellular response to glucose starvation; cellular response to insulin stimulus; cellular senescence; collagen metabolic process; cytosol; defense response to bacterium; endoplasmic reticulum; enzyme activator activity; intracellular signal transduction; metal ion binding; mitochondrion; negative regulation of MAP kinase activity; negative regulation of actin filament polymerization; negative regulation of filopodium assembly; negative regulation of glial cell apoptotic process; negative regulation of insulin receptor signaling pathway; negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of platelet aggregation; neutrophil activation; nucleus; peptidyl-threonine phosphorylation; perinuclear region of cytoplasm; plasma membrane; positive regulation of MAP kinase activity; positive regulation of apoptotic process; positive regulation of ceramide biosynthetic process; positive regulation of glucose import; positive regulation of glucosylceramide catabolic process; positive regulation of phospholipid scramblase activity; positive regulation of protein dephosphorylation; positive regulation of response to DNA damage stimulus; positive regulation of sphingomyelin catabolic process; positive regulation of superoxide anion generation; protein autophosphorylation; response to amino acid stimulus; response to drug; response to ethanol; response to glucose stimulus; response to heat; response to hydrogen peroxide; response to hypoxia; response to mechanical stimulus; response to organic cyclic compound; termination of signal transduction,PF00130;PF00069;PF00433;,4.00E-80,CHOYP_LOC100370583.1.1,,,,,,,KPCD_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; apoptotic process [GO:0006915]; aspartate transport [GO:0015810]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to glucose starvation [GO:0042149]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; collagen metabolic process [GO:0032963]; defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of platelet aggregation [GO:0090331]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of glucose import [GO:0046326]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of superoxide anion generation [GO:0032930]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of phosphorylation [GO:0042325]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979] comp121234_c0_seq1,970,45.1546,0.85060055,11,94,,2.00E-100,P51688,N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),GO:0016250; GO:0005975; GO:0003824; GO:0006027; GO:0043202; GO:0046872; GO:0006029; GO:0044281; GO:0008484,N-sulfoglucosamine sulfohydrolase activity; carbohydrate metabolic process; catalytic activity; glycosaminoglycan catabolic process; lysosomal lumen; metal ion binding; proteoglycan metabolic process; small molecule metabolic process; sulfuric ester hydrolase activity,PF16347;PF00884;,,,,,,,,,SPHM_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] comp121234_c0_seq2,627,45.7735,0.73586751,4,0,,9.00E-72,P51688,N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),GO:0016250; GO:0005975; GO:0003824; GO:0006027; GO:0043202; GO:0046872; GO:0006029; GO:0044281; GO:0008484,N-sulfoglucosamine sulfohydrolase activity; carbohydrate metabolic process; catalytic activity; glycosaminoglycan catabolic process; lysosomal lumen; metal ion binding; proteoglycan metabolic process; small molecule metabolic process; sulfuric ester hydrolase activity,PF16347;PF00884;,5.00E-18,CHOYP_LOC100378056.1.1,,,,,,,SPHM_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] comp121236_c0_seq1,1352,41.8639,0.51379775,32,147,,4.00E-150,Q99MP8,BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP),BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP),GO:0000165; GO:0007265; GO:0005737; GO:0009968; GO:0008139; GO:0000166; GO:0000151; GO:0004842; GO:0008270,MAPK cascade; Ras protein signal transduction; cytoplasm; negative regulation of signal transduction; nuclear localization sequence binding; nucleotide binding; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding,PF07576;PF13639;PF02148;,7.00E-77,CHOYP_BRAP.1.1,,,,,,,BRAP_MOUSE,Mus musculus (Mouse),MAPK cascade [GO:0000165]; negative regulation of signal transduction [GO:0009968]; protein ubiquitination [GO:0016567]; Ras protein signal transduction [GO:0007265] comp121244_c1_seq1,1504,44.4149,0.32532642,88,57,,1.00E-23,Q9NU22,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0016887; GO:0005730; GO:0005634; GO:0006461; GO:0051082,ATP binding; ATPase activity; nucleolus; nucleus; protein complex assembly; unfolded protein binding,PF07728;,,,,,,,,,MDN1_HUMAN,Homo sapiens (Human),protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027] comp121245_c0_seq2,349,43.8395,0.73427176,0,21,,,,,,,,,5.00E-21,CHOYP_LOC100647948.1.1,,,,,,,,, comp121250_c1_seq1,560,38.0357,0.31635439,20,80,,8.00E-25,Q6AXC6,Probable ATP-dependent RNA helicase DDX11 (EC 3.6.4.13) (DEAD/H box protein 11),Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H box protein 11),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0008094; GO:0003723; GO:0004386; GO:0046872; GO:0030496; GO:0000790; GO:0005730; GO:0007062; GO:0000922,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA-dependent ATPase activity; RNA binding; helicase activity; metal ion binding; midbody; nuclear chromatin; nucleolus; sister chromatid cohesion; spindle pole",PF06733;PF13307;,,,,,,,,,DDX11_MOUSE,Mus musculus (Mouse),nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062] comp121250_c2_seq1,251,42.2311,0.19741794,1,18,,9.00E-14,A2QY22,ATP-dependent RNA helicase chl1 (EC 3.6.4.13) (Chromosome loss protein 1),ATP-dependent DNA helicase chl1 (EC 3.6.4.12) (Chromosome loss protein 1),GO:0005524; GO:0004003; GO:0003677; GO:0007049; GO:0005634,ATP binding; ATP-dependent DNA helicase activity; DNA binding; cell cycle; nucleus,PF06733;PF13307;,4.00E-14,CHOYP_DDX11.1.1,,,,,,,CHL1_ASPNC,Aspergillus niger (strain CBS 513.88 / FGSC A1513),cell cycle [GO:0007049]; nucleobase-containing compound metabolic process [GO:0006139] comp121258_c0_seq1,829,45.4765,0.5694691,22,82,,1.00E-08,Q49A88,Coiled-coil domain-containing protein 14,Coiled-coil domain-containing protein 14,GO:0005813,centrosome,PF15254;,,,,,,,,,CCD14_HUMAN,Homo sapiens (Human),protein localization to centrosome [GO:0071539]; substantia nigra development [GO:0021762] comp121268_c0_seq1,1050,43.3333,0.3477697,65,3,,3.00E-44,Q8NCR3,Uncharacterized protein C11orf65,Uncharacterized protein C11orf65,,,,3.00E-74,CHOYP_LOC100371204.1.1,,,,,,,CK065_HUMAN,Homo sapiens (Human), comp121268_c2_seq1,574,47.0383,0.51111266,39,11,,,,,,,,,6.00E-35,CHOYP_LOC100371204.1.1,,,,,,,,, comp121269_c1_seq1,272,44.4853,0.61905599,0,27,,8.00E-10,P82349,Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG),Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG),GO:0035051; GO:0005737; GO:0005856; GO:0005887; GO:0061024; GO:0007517; GO:0016012; GO:0042383,cardiocyte differentiation; cytoplasm; cytoskeleton; integral to plasma membrane; membrane organization; muscle organ development; sarcoglycan complex; sarcolemma,PF04790;,,,,,,,,,SGCB_MOUSE,Mus musculus (Mouse),cardiac muscle cell development [GO:0055013]; membrane organization [GO:0061024]; muscle fiber development [GO:0048747]; muscle organ development [GO:0007517]; vascular smooth muscle cell development [GO:0097084] comp121279_c0_seq2,646,40.4025,0.99023077,9,34,,2.00E-10,P03556,Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF02160;PF00078;,,,,,,,,,POL_CAMVD,Cauliflower mosaic virus (strain D/H) (CaMV), comp121279_c0_seq3,635,40.4724,1.00327879,0,9,,5.00E-08,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp121289_c1_seq1,340,42.6471,0.53490659,6,34,,5.00E-41,Q9UBT6,DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP),DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP),GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0046872; GO:0006297; GO:0005634,"DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; metal ion binding; nucleotide-excision repair, DNA gap filling; nucleus",PF00817;PF11799;PF11798;,1.00E-40,CHOYP_POLK.1.1,,,,,,,POLK_HUMAN,Homo sapiens (Human),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp121289_c2_seq1,340,40.8824,0.44019314,10,27,,2.00E-14,Q9QUG2,DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP),DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP),GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0046872; GO:0006297; GO:0005634,"DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; metal ion binding; nucleotide-excision repair, DNA gap filling; nucleus",PF00817;PF11799;,,,,,,,,,POLK_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleotide-excision repair, DNA gap filling [GO:0006297]" comp121295_c0_seq2,1685,42.4926,0.6236677,17,5,,,,,,,,,1.00E-31,CHOYP_TVAG_355490.19.22,,,,,,,,, comp121309_c1_seq1,720,51.1111,0.45943164,10,27,,3.00E-29,Q6UUV9,CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1),CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1),GO:0008140; GO:0005737; GO:0019048; GO:0005634; GO:0005886; GO:0032793; GO:0045944; GO:0051289; GO:0006351,"cAMP response element binding protein binding; cytoplasm; modulation by virus of host morphology or physiology; nucleus; plasma membrane; positive regulation of CREB transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; protein homotetramerization; transcription, DNA-dependent",PF12886;PF12885;PF12884;,4.00E-26,CHOYP_LOC100378719.1.1,,,,,,,CRTC1_HUMAN,Homo sapiens (Human),"entrainment of circadian clock by photoperiod [GO:0043153]; membrane hyperpolarization [GO:0060081]; memory [GO:0007613]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendrite development [GO:1900006]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein homotetramerization [GO:0051289]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp121310_c1_seq2,514,40.0778,0.53722347,12,10,,1.00E-08,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp121315_c1_seq1,1080,41.3889,1.02141135,31,99,,3.00E-40,P00184,Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-P1),Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-P1),GO:0042904; GO:0007568; GO:0009308; GO:0070330; GO:0043010; GO:0008283; GO:0009804; GO:0032451; GO:0048565; GO:0017144; GO:0009792; GO:0005789; GO:0016711; GO:0009812; GO:0020037; GO:0070365; GO:0046483; GO:0050665; GO:0017143; GO:0005506; GO:0060137; GO:0005739; GO:0016679; GO:0016712; GO:0006778; GO:0046677; GO:0046685; GO:0042493; GO:0032094; GO:0009635; GO:0055093; GO:0001666; GO:0010041; GO:0032496; GO:0009624; GO:0014070; GO:0009636; GO:0009615; GO:0033189; GO:0009611; GO:0008395; GO:0009404; GO:0070576,"9-cis-retinoic acid biosynthetic process; aging; amine metabolic process; aromatase activity; camera-type eye development; cell proliferation; coumarin metabolic process; demethylase activity; digestive tract development; drug metabolic process; embryo development ending in birth or egg hatching; endoplasmic reticulum membrane; flavonoid 3'-monooxygenase activity; flavonoid metabolic process; heme binding; hepatocyte differentiation; heterocycle metabolic process; hydrogen peroxide biosynthetic process; insecticide metabolic process; iron ion binding; maternal process involved in parturition; mitochondrion; oxidoreductase activity, acting on diphenols and related substances as donors; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; porphyrin-containing compound metabolic process; response to antibiotic; response to arsenic-containing substance; response to drug; response to food; response to herbicide; response to hyperoxia; response to hypoxia; response to iron(III) ion; response to lipopolysaccharide; response to nematode; response to organic cyclic compound; response to toxic substance; response to virus; response to vitamin A; response to wounding; steroid hydroxylase activity; toxin metabolic process; vitamin D 24-hydroxylase activity",PF00067;,,,,,,,,,CP1A1_MOUSE,Mus musculus (Mouse),9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; digestive tract development [GO:0048565]; drug metabolic process [GO:0017144]; embryo development ending in birth or egg hatching [GO:0009792]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; maternal process involved in parturition [GO:0060137]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611]; toxin metabolic process [GO:0009404] comp121326_c0_seq1,300,45.3333,0.65152239,2,53,,3.00E-24,Q92051,Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase),Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase),GO:0015670; GO:0004089; GO:0042539; GO:0006730; GO:0008270,carbon dioxide transport; carbonate dehydratase activity; hypotonic salinity response; one-carbon metabolic process; zinc ion binding,PF00194;,3.00E-16,CHOYP_CAH6.1.1,,,,,,,CAHZ_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] comp121326_c2_seq1,675,42.2222,0.90017953,0,150,,1.00E-12,Q27504,Putative carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase 3),Putative carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase 3),GO:0004089; GO:0006730; GO:0008270,carbonate dehydratase activity; one-carbon metabolic process; zinc ion binding,PF00194;,,,6.00E-21,ruditapes_c15307,,,,,CAH3_CAEEL,Caenorhabditis elegans,one-carbon metabolic process [GO:0006730] comp121328_c0_seq1,415,40,1.07152137,13,22,,9.00E-18,Q9VRJ2,FIT family protein CG10671,FIT family protein CG10671,GO:0005789; GO:0016021; GO:0019915,endoplasmic reticulum membrane; integral to membrane; lipid storage,PF10261;,,,,,,,,,FITM_DROME,Drosophila melanogaster (Fruit fly),lipid particle organization [GO:0034389]; lipid storage [GO:0019915]; phospholipid biosynthetic process [GO:0008654] comp121329_c0_seq1,1924,38.3056,1.01255769,3055,1,male>female,4.00E-09,Q5UPG5,Putative ankyrin repeat protein L93,Putative ankyrin repeat protein L93,,,PF12796;PF13606;,,,,,,,,,YL093_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp121332_c1_seq1,384,43.4896,0.44534715,10,15,,2.00E-29,P23471,Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2),Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2),GO:0007409; GO:0007417; GO:0005887; GO:0072534; GO:0008330; GO:0005578; GO:0005001,axonogenesis; central nervous system development; integral to plasma membrane; perineuronal net; protein tyrosine/threonine phosphatase activity; proteinaceous extracellular matrix; transmembrane receptor protein tyrosine phosphatase activity,PF00194;PF00041;PF00102;,7.00E-20,CHOYP_LOC660278.1.2,,,,,,,PTPRZ_HUMAN,Homo sapiens (Human),axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; hematopoietic progenitor cell differentiation [GO:0002244]; hippocampus development [GO:0021766]; learning or memory [GO:0007611]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of dendrite development [GO:2000171]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of dendrite development [GO:1900006]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron migration [GO:2001224]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of Schwann cell migration [GO:1900149]; protein dephosphorylation [GO:0006470]; regulation of dendrite morphogenesis [GO:0048814]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; visual learning [GO:0008542] comp121340_c0_seq1,392,51.0204,0.79242375,24,28,,8.00E-10,Q01577,Serine/threonine-protein kinase pkpA (EC 2.7.11.1),Serine/threonine-protein kinase pkpA (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PKPA_PHYBL,Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555), comp121340_c1_seq1,648,45.9877,0.67284361,25,50,,2.00E-18,Q9I7U4,Titin (D-Titin) (Kettin),Titin (D-Titin) (Kettin),GO:0030018; GO:0003779; GO:0051301; GO:0000794; GO:0040011; GO:0007498; GO:0005875; GO:0007076; GO:0016203; GO:0007520; GO:0035206; GO:0045214; GO:0007062; GO:0007519; GO:0007525; GO:0008307; GO:0007522,Z disc; actin binding; cell division; condensed nuclear chromosome; locomotion; mesoderm development; microtubule associated complex; mitotic chromosome condensation; muscle attachment; myoblast fusion; regulation of hemocyte proliferation; sarcomere organization; sister chromatid cohesion; skeletal muscle tissue development; somatic muscle development; structural constituent of muscle; visceral muscle development,PF06582;PF00041;PF07679;PF00018;,,,,,,,,,TITIN_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522] comp121340_c2_seq1,967,47.1562,0.67192483,7,0,,2.00E-64,Q86YV6,Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085),Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,1.00E-115,CHOYP_PHUM_PHUM226120.4.7,,,,,,,MYLK4_HUMAN,Homo sapiens (Human), comp121340_c2_seq2,931,46.8314,0.68709927,5,13,,9.00E-82,O02827,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] (Fragment)","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] (Fragment)",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity,PF07679;PF00069;,3.00E-123,CHOYP_UNC22.2.2,,,,,,,MYLK_SHEEP,Ovis aries (Sheep), comp121349_c0_seq1,628,39.4904,1.14728973,12,111,,1.00E-39,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,2.00E-15,CHOYP_LOC100118063.4.4,1.00E-17,ruditapes_c10345,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp121369_c0_seq1,750,41.8667,0.71117551,28,70,,4.00E-30,D3ZQG6,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,1.00E-27,CHOYP_LOC100645486.1.1,,,,,,,TRIM2_RAT,Rattus norvegicus (Rat),regulation of neuron apoptotic process [GO:0043523] comp121385_c0_seq1,815,42.0859,0.67985323,18,67,,,,,,,,,6.00E-12,CHOYP_LOC100889329.1.1,,,,,,,,, comp121389_c0_seq1,984,44.4106,0.87915887,79,78,,7.00E-06,Q8CHD8,Rab11 family-interacting protein 3 (FIP3-Rab11) (Rab11-FIP3),Rab11 family-interacting protein 3 (FIP3-Rab11) (Rab11-FIP3),GO:0030306; GO:0017137; GO:0005509; GO:0005813; GO:0032154; GO:0000910; GO:0032456; GO:0005825; GO:0016020; GO:0030496; GO:0005634; GO:0042803; GO:0055037; GO:0055038,ADP-ribosylation factor binding; Rab GTPase binding; calcium ion binding; centrosome; cleavage furrow; cytokinesis; endocytic recycling; half bridge of spindle pole body; membrane; midbody; nucleus; protein homodimerization activity; recycling endosome; recycling endosome membrane,PF09457;,1.00E-46,CHOYP_LOC100377856.2.2,,,,,,,RFIP3_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; negative regulation of adiponectin secretion [GO:0070164]; protein localization to cilium [GO:0061512] comp121401_c1_seq1,1533,42.4005,0.75867677,60,145,,2.00E-161,Q5F356,Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha),Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha),GO:0016309; GO:0005524; GO:0005737; GO:0005634; GO:0046854; GO:0005886,1-phosphatidylinositol-5-phosphate 4-kinase activity; ATP binding; cytoplasm; nucleus; phosphatidylinositol phosphorylation; plasma membrane,PF01504;,5.00E-117,CHOYP_LOC100373656.1.1,,,,,,,PI42A_CHICK,Gallus gallus (Chicken), comp121404_c0_seq3,341,39.8827,0.74542925,0,0,,1.00E-06,P07247,Protein krueppel,Protein krueppel,GO:0061332; GO:0003705; GO:0007411; GO:0006342; GO:0048749; GO:0007402; GO:0046872; GO:0007517; GO:0000122; GO:0007400; GO:0005634; GO:0040034; GO:0035206; GO:0043565; GO:0035290; GO:0007419; GO:0035220; GO:0007354,"Malpighian tubule bud morphogenesis; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; axon guidance; chromatin silencing; compound eye development; ganglion mother cell fate determination; metal ion binding; muscle organ development; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleus; regulation of development, heterochronic; regulation of hemocyte proliferation; sequence-specific DNA binding; trunk segmentation; ventral cord development; wing disc development; zygotic determination of anterior/posterior axis, embryo",,,,,,,,,,KRUP_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; chromatin silencing [GO:0006342]; compound eye development [GO:0048749]; ganglion mother cell fate determination [GO:0007402]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; muscle organ development [GO:0007517]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; regulation of development, heterochronic [GO:0040034]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; wing disc development [GO:0035220]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]" comp121406_c0_seq1,2042,34.427,0.56736108,723,3303,,0,Q6IR75,COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Fragment),COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Fragment),GO:0008180; GO:0005737,COP9 signalosome; cytoplasm,PF01399;,0,CHOYP_CSN2.1.1,,,,,,,CSN2_XENLA,Xenopus laevis (African clawed frog), comp121414_c2_seq2,2525,45.2277,0.3113522,99,43,,5.00E-120,Q5SSH7,Zinc finger ZZ-type and EF-hand domain-containing protein 1,Zinc finger ZZ-type and EF-hand domain-containing protein 1,GO:0005509; GO:0008270,calcium ion binding; zinc ion binding,PF03256;PF00569;,2.00E-80,CHOYP_BRAFLDRAFT_88583.1.1,,,,,,,ZZEF1_MOUSE,Mus musculus (Mouse), comp121421_c0_seq1,1271,45.8694,0.63154947,56,15,,1.00E-169,A1L0Y2,Neuralized-like protein 4,Neuralized-like protein 4,GO:0005814,centriole,PF07177;,2.00E-160,CHOYP_NEUL4.2.2,,,,,,,NEUL4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp121421_c1_seq1,390,46.1538,0.45052146,24,10,,,,,,,,,1.00E-17,CHOYP_BLUE.1.1,,,,,,,,, comp121427_c0_seq2,879,42.2071,0.49078377,43,78,,2.00E-17,Q80VP2,Spermatogenesis-associated protein 7 homolog,Spermatogenesis-associated protein 7 homolog,GO:0050896; GO:0007601,response to stimulus; visual perception,PF15244;,9.00E-23,CHOYP_BRAFLDRAFT_65681.1.1,,,,,,,SPAT7_MOUSE,Mus musculus (Mouse),photoreceptor cell maintenance [GO:0045494]; protein localization to photoreceptor connecting cilium [GO:1903621]; protein localization to photoreceptor outer segment [GO:1903546]; response to stimulus [GO:0050896]; spermatogenesis [GO:0007283]; visual perception [GO:0007601] comp121430_c0_seq1,577,45.0607,0.62906048,22,20,,2.00E-41,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp121430_c1_seq2,289,40.8304,0.67896628,0,0,,,,,,,,,1.00E-21,CHOYP_UBP24.1.1,,,,,,,,, comp121431_c0_seq1,1730,42.1965,0.39096569,42,255,,,,,,,,,5.00E-80,CHOYP_ZN207.1.1,,,,,,,,, comp121431_c0_seq2,1745,42.235,0.38681961,0,19,,1.00E-48,O43670,Zinc finger protein 207,BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (hBuGZ) (Zinc finger protein 207),GO:0003677; GO:0008201; GO:0005634; GO:0003700; GO:0008270,DNA binding; heparin binding; nucleus; sequence-specific DNA binding transcription factor activity; zinc ion binding,,,,,,,,,,ZN207_HUMAN,Homo sapiens (Human),"attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint [GO:0007094]; protein stabilization [GO:0050821]; regulation of chromosome segregation [GO:0051983]; regulation of transcription, DNA-templated [GO:0006355]" comp121432_c0_seq1,288,41.3194,0.41884563,2,29,,6.00E-08,Q09225,Nose resistant to fluoxetine protein 6 (Protein nrf-6),Nose resistant to fluoxetine protein 6 (Protein nrf-6),GO:0016021; GO:0008289; GO:0006869; GO:0007275; GO:0016747,"integral to membrane; lipid binding; lipid transport; multicellular organismal development; transferase activity, transferring acyl groups other than amino-acyl groups",PF01757;,,,,,,,,,NRF6_CAEEL,Caenorhabditis elegans,lipid transport [GO:0006869]; multicellular organism development [GO:0007275] comp121432_c1_seq1,510,34.5098,0.93358052,25,7,,,,,,,,,4.00E-12,CHOYP_LOC100904451.4.11,,,,,,,,, comp121435_c0_seq2,790,42.5316,0.3969182,19,9,,7.00E-57,Q562C6,Leucine zipper transcription factor-like protein 1,Leucine zipper transcription factor-like protein 1,GO:0005737; GO:0072594,cytoplasm; establishment of protein localization to organelle,,3.00E-60,CHOYP_BRAFLDRAFT_268354.1.1,,,,,,,LZTL1_RAT,Rattus norvegicus (Rat),negative regulation of protein localization to ciliary membrane [GO:1903568] comp121450_c0_seq1,239,41.0042,0.72415061,0,2,,1.00E-06,Q24564,Moesin/ezrin/radixin homolog 2 (Ezrin-moesin-radixin 2) (Merlin) (dMerlin),Moesin/ezrin/radixin homolog 2 (Ezrin-moesin-radixin 2) (Merlin) (dMerlin),GO:0036375; GO:0016006; GO:0005912; GO:0016324; GO:0005938; GO:0007050; GO:0007267; GO:0001751; GO:0008092; GO:0005856; GO:0008101; GO:0032456; GO:0006897; GO:0019898; GO:0035329; GO:0007476; GO:0007112; GO:0060253; GO:0046621; GO:0042048; GO:0019094; GO:0042327; GO:0042981; GO:0001558; GO:0046669; GO:0035330; GO:0006355; GO:0007291; GO:0006351,"Kibra-Ex-Mer complex; Nebenkern; adherens junction; apical plasma membrane; cell cortex; cell cycle arrest; cell-cell signaling; compound eye photoreceptor cell differentiation; cytoskeletal protein binding; cytoskeleton; decapentaplegic signaling pathway; endocytic recycling; endocytosis; extrinsic to membrane; hippo signaling cascade; imaginal disc-derived wing morphogenesis; male meiosis cytokinesis; negative regulation of glial cell proliferation; negative regulation of organ growth; olfactory behavior; pole plasm mRNA localization; positive regulation of phosphorylation; regulation of apoptotic process; regulation of cell growth; regulation of compound eye retinal cell programmed cell death; regulation of hippo signaling cascade; regulation of transcription, DNA-dependent; sperm individualization; transcription, DNA-dependent",PF00769;PF09380;PF00373;PF09379;,,,,,,,,,MERH_DROME,Drosophila melanogaster (Fruit fly),"axis specification [GO:0009798]; cell-cell signaling [GO:0007267]; cell cycle arrest [GO:0007050]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; decapentaplegic signaling pathway [GO:0008101]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; hippo signaling [GO:0035329]; imaginal disc-derived wing morphogenesis [GO:0007476]; male meiosis cytokinesis [GO:0007112]; meiotic chromosome separation [GO:0051307]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of organ growth [GO:0046621]; olfactory behavior [GO:0042048]; pole plasm mRNA localization [GO:0019094]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell growth [GO:0001558]; regulation of cell proliferation [GO:0042127]; regulation of compound eye retinal cell programmed cell death [GO:0046669]; regulation of hippo signaling [GO:0035330]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; transcription, DNA-templated [GO:0006351]" comp121450_c1_seq1,383,46.7363,0.38788143,22,43,,6.00E-17,P59750,Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin),Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin),GO:0042995; GO:0005737; GO:0005856; GO:0019898; GO:0008285; GO:0005634; GO:0005886,cell projection; cytoplasm; cytoskeleton; extrinsic to membrane; negative regulation of cell proliferation; nucleus; plasma membrane,PF00769;PF09380;PF00373;PF09379;,,,,,,,,,MERL_PAPAN,Papio anubis (Olive baboon),actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010] comp121451_c0_seq1,648,43.9815,0.7427864,18,92,,8.00E-32,Q96L50,Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5),Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5),GO:0016567,protein ubiquitination,PF12799;PF13516;,,,,,,,,,LLR1_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp121453_c0_seq1,1027,40.3116,0.64924275,71,10,,8.00E-64,Q640N2,ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1),ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) (Protein hennin),GO:0005525; GO:0005929; GO:0007368; GO:0009953; GO:0007264,GTP binding; cilium; determination of left/right symmetry; dorsal/ventral pattern formation; small GTPase mediated signal transduction,PF00025;,6.00E-19,CHOYP_LOC100375027.1.1,,,,,,,AR13B_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; formation of radial glial scaffolds [GO:0021943]; heart looping [GO:0001947]; interneuron migration from the subpallium to the cortex [GO:0021830]; left/right axis specification [GO:0070986]; neural tube patterning [GO:0021532]; nonmotile primary cilium assembly [GO:0035058]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224] comp121458_c0_seq1,744,44.086,0.5183219,17,39,,7.00E-42,Q8N3Y7,Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5),Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5),GO:0050908; GO:0005789; GO:0016021; GO:0043616; GO:0042574; GO:0004745; GO:0042572,detection of light stimulus involved in visual perception; endoplasmic reticulum membrane; integral to membrane; keratinocyte proliferation; retinal metabolic process; retinol dehydrogenase activity; retinol metabolic process,PF00106;,,,2.00E-41,ruditapes_c7765,,,,,RDHE2_HUMAN,Homo sapiens (Human),detection of light stimulus involved in visual perception [GO:0050908]; keratinocyte proliferation [GO:0043616]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] comp121462_c0_seq1,414,39.8551,0.42720837,12,10,,,,,,,,,3.00E-12,CHOYP_TCB2.2.2,,,,,,,,, comp121464_c0_seq1,518,44.9807,0.30597019,3,2,,,,,,,,,7.00E-34,CHOYP_UBA6.4.4,,,,,,,,, comp121464_c1_seq1,1110,44.8649,0.61066703,0,0,,2.00E-42,P41226,Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (D8) (Ubiquitin-activating enzyme E1 homolog),Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (D8) (Ubiquitin-activating enzyme E1 homolog),GO:0005524; GO:0019782; GO:0032020; GO:0019221; GO:0005829; GO:0045087; GO:0016874; GO:0019941; GO:0032480; GO:0016567,ATP binding; ISG15 activating enzyme activity; ISG15-protein conjugation; cytokine-mediated signaling pathway; cytosol; innate immune response; ligase activity; modification-dependent protein catabolic process; negative regulation of type I interferon production; protein ubiquitination,PF16191;PF16190;PF09358;PF00899;PF10585;,,,,,,,,,UBA7_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of type I interferon production [GO:0032480]; translesion synthesis [GO:0019985] comp121464_c1_seq2,1184,45.2703,0.59535316,2,14,,2.00E-131,A0AVT1,Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2),Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2),GO:0005524; GO:0019780; GO:0005737; GO:0016874; GO:0016567; GO:0006511,ATP binding; FAT10 activating enzyme activity; cytoplasm; ligase activity; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF16191;PF16190;PF09358;PF00899;PF10585;,,,,,,,,,UBA6_HUMAN,Homo sapiens (Human),amygdala development [GO:0021764]; dendritic spine development [GO:0060996]; hippocampus development [GO:0021766]; learning [GO:0007612]; locomotory behavior [GO:0007626]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511] comp121467_c0_seq1,212,40.566,0.86286642,4,0,,7.00E-13,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp121468_c0_seq1,524,44.2748,0.58633227,2,25,,2.00E-20,P24482,DNA polymerase epsilon subunit B (EC 2.7.7.7) (DNA polymerase II subunit 2),DNA polymerase epsilon subunit B (EC 2.7.7.7) (DNA polymerase II subunit 2),GO:0003677; GO:0003887; GO:0007049; GO:0005737; GO:0008622; GO:0042276; GO:0070868; GO:0045005,DNA binding; DNA-directed DNA polymerase activity; cell cycle; cytoplasm; epsilon DNA polymerase complex; error-prone translesion synthesis; heterochromatin organization involved in chromatin silencing; maintenance of fidelity involved in DNA-dependent DNA replication,PF04042;,,,,,,,,,DPB2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cell cycle [GO:0007049]; DNA-dependent DNA replication [GO:0006261]; DNA-dependent DNA replication maintenance of fidelity [GO:0045005]; error-prone translesion synthesis [GO:0042276]; heterochromatin organization involved in chromatin silencing [GO:0070868] comp121468_c0_seq2,642,42.6791,0.58289482,5,38,,5.00E-83,Q5ZKQ6,DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B),DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B),GO:0003677; GO:0006281; GO:0006261; GO:0003887; GO:0008622,DNA binding; DNA repair; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; epsilon DNA polymerase complex,PF04042;PF12213;,5.00E-87,CHOYP_DPOE2.1.1,,,,,,,DPOE2_CHICK,Gallus gallus (Chicken),DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] comp121473_c0_seq1,1086,40.6998,0.53414185,0,0,,4.00E-34,Q8JZL0,Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI),Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN467_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121473_c0_seq2,1217,36.7297,0.48896059,6,22,,4.00E-57,Q15937,Zinc finger protein 79 (ZNFpT7),Zinc finger protein 79 (ZNFpT7),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZNF79_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121473_c0_seq4,654,44.6483,0.4927834,2,15,,1.00E-05,P0C7X2,Zinc finger protein 688,Zinc finger protein 688,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN688_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121481_c0_seq2,1038,40.8478,0.50858894,4,19,,3.00E-174,Q2M389,WASH complex subunit 7,WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP),GO:0071203; GO:0016197; GO:0005768,WASH complex; endosomal transport; endosome,PF14746;PF14744;PF14745;,3.00E-162,CHOYP_LOC100372619.2.2,,,,,,,WASH7_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031] comp121481_c0_seq3,963,39.6677,0.58327896,0,7,,6.00E-152,Q2M389,WASH complex subunit 7,WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP),GO:0071203; GO:0016197; GO:0005768,WASH complex; endosomal transport; endosome,PF14746;PF14744;PF14745;,1.00E-148,CHOYP_BRAFLDRAFT_221115.1.1,,,,,,,WASH7_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031] comp121487_c0_seq3,896,43.9732,0.30124815,0,0,,9.00E-08,Q17QR8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_BOVIN,Bos taurus (Bovine), comp121501_c0_seq1,509,46.3654,0.84057861,0,80,,1.00E-09,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp121513_c1_seq1,1353,44.8633,0.47118213,79,61,,2.00E-62,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,8.00E-51,CHOYP_LOC100748709.1.1,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp121513_c2_seq1,261,45.5939,0.37322485,19,0,,6.00E-06,Q2LD37,Uncharacterized protein KIAA1109 (Fragile site-associated protein),Uncharacterized protein KIAA1109 (Fragile site-associated protein),GO:0016021; GO:0016020; GO:0005634; GO:0001558; GO:0030856,integral to membrane; membrane; nucleus; regulation of cell growth; regulation of epithelial cell differentiation,PF10479;,1.00E-26,CHOYP_LOC100748709.1.1,,,,,,,K1109_HUMAN,Homo sapiens (Human),regulation of cell growth [GO:0001558]; regulation of epithelial cell differentiation [GO:0030856] comp121539_c0_seq1,467,41.1135,0.41507951,11,69,,2.00E-12,Q96LW4,Coiled-coil domain-containing protein 111 (DNA-directed primase/polymerase protein),DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111),GO:0003896,DNA primase activity,,,,,,,,,,CC111_HUMAN,Homo sapiens (Human),mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp121545_c1_seq1,1382,41.3169,0.36098908,34,108,,5.00E-31,Q5EBP3,Armadillo repeat-containing protein 5,Armadillo repeat-containing protein 5,,,PF00651;,,,,,,,,,ARMC5_MOUSE,Mus musculus (Mouse), comp121546_c1_seq1,257,43.5798,0.49378738,0,0,,5.00E-08,Q9JYC0,50S ribosomal protein L3 glutamine methyltransferase (L3 MTase) (EC 2.1.1.n15) (N5-glutamine methyltransferase PrmB),50S ribosomal protein L3 glutamine methyltransferase (L3 MTase) (EC 2.1.1.298) (N5-glutamine methyltransferase PrmB),GO:0005622; GO:0003676; GO:0008276; GO:0009007,intracellular; nucleic acid binding; protein methyltransferase activity; site-specific DNA-methyltransferase (adenine-specific) activity,PF05175;,,,,,,,,,PRMB_NEIMB,Neisseria meningitidis serogroup B (strain MC58),peptidyl-glutamine methylation [GO:0018364] comp121546_c1_seq2,306,42.4837,0.51057804,0,0,,7.00E-13,Q748B2,Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.n16) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC),Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC),GO:0003676; GO:0018364; GO:0036009,nucleic acid binding; peptidyl-glutamine methylation; protein-glutamine N-methyltransferase activity,PF05175;,,,,,,,,,PRMC_GEOSL,Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA),peptidyl-glutamine methylation [GO:0018364] comp121546_c1_seq3,409,41.3203,0.29462665,6,44,,2.00E-31,Q921L7,HemK methyltransferase family member 1 (EC 2.1.1.-),HemK methyltransferase family member 1 (EC 2.1.1.-),GO:0005739; GO:0003676; GO:0008276,mitochondrion; nucleic acid binding; protein methyltransferase activity,PF05175;,,,,,,,,,HEMK1_MOUSE,Mus musculus (Mouse), comp121566_c0_seq1,415,41.6867,0.72688594,4,91,,1.00E-17,Q15262,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0005912; GO:0030424; GO:0016477; GO:0009986; GO:0005911; GO:0034644; GO:0034614; GO:0030425; GO:0048041; GO:0005887; GO:0031256; GO:0045786; GO:0030336; GO:0010839; GO:0045892; GO:0043025; GO:0001750; GO:0034394; GO:0007179; GO:0005001,"adherens junction; axon; cell migration; cell surface; cell-cell junction; cellular response to UV; cellular response to reactive oxygen species; dendrite; focal adhesion assembly; integral to plasma membrane; leading edge membrane; negative regulation of cell cycle; negative regulation of cell migration; negative regulation of keratinocyte proliferation; negative regulation of transcription, DNA-dependent; neuronal cell body; photoreceptor outer segment; protein localization to cell surface; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein tyrosine phosphatase activity",PF00041;PF07679;PF00629;PF00102;,,,,,,,,,PTPRK_HUMAN,Homo sapiens (Human),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp121573_c1_seq1,930,41.2903,0.72250638,39,62,,2.00E-77,Q969R2,Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4),Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4),GO:0015485; GO:0006869; GO:0016020; GO:0005543,cholesterol binding; lipid transport; membrane; phospholipid binding,PF01237;PF00169;,1.00E-46,CHOYP_LOC100372322.1.1,,,,,,,OSBP2_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869]; spermatid development [GO:0007286] comp121573_c2_seq2,1352,43.5651,0.53273914,17,33,,4.00E-80,Q3B7Z2,Oxysterol-binding protein 1,Oxysterol-binding protein 1,GO:0000139; GO:0006869; GO:0005543,Golgi membrane; lipid transport; phospholipid binding,PF01237;PF00169;,,,,,,,,,OSBP1_MOUSE,Mus musculus (Mouse),positive regulation of growth of symbiont in host [GO:0044128]; sterol transport [GO:0015918] comp121573_c2_seq3,239,42.2594,0.37647718,1,0,,2.00E-18,Q9BZF2,Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7),Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7),GO:0005776; GO:0071397; GO:0015485; GO:0005829; GO:0006869; GO:0097038; GO:0005543; GO:0005886; GO:1901800,autophagic vacuole; cellular response to cholesterol; cholesterol binding; cytosol; lipid transport; perinuclear endoplasmic reticulum; phospholipid binding; plasma membrane; positive regulation of proteasomal protein catabolic process,PF01237;,,,,,,,,,OSBL7_HUMAN,Homo sapiens (Human),cellular response to cholesterol [GO:0071397]; lipid transport [GO:0006869]; positive regulation of proteasomal protein catabolic process [GO:1901800] comp121573_c2_seq4,865,45.5491,0.51708273,0,0,,5.00E-82,Q3B7Z2,Oxysterol-binding protein 1,Oxysterol-binding protein 1,GO:0000139; GO:0006869; GO:0005543,Golgi membrane; lipid transport; phospholipid binding,PF01237;PF00169;,2.00E-75,CHOYP_OSBP1.1.1,,,,,,,OSBP1_MOUSE,Mus musculus (Mouse),positive regulation of growth of symbiont in host [GO:0044128]; sterol transport [GO:0015918] comp121576_c1_seq1,419,43.1981,0.41035896,18,11,,9.00E-15,Q5RA75,Protein FAM135A,Protein FAM135A,,,PF12394;PF05057;,,,,,,,,,F135A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp121577_c0_seq1,849,45.3475,0.5305875,35,6,,3.00E-94,Q7ZVL2,WD repeat-containing protein 24,WD repeat-containing protein 24,,,PF00400;,2.00E-36,CHOYP_BRAFLDRAFT_60509.1.1,,,,,,,WDR24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp121580_c2_seq1,558,46.4158,0.83393274,8,41,,2.00E-82,Q8BZN4,NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2),NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2),GO:0005524; GO:0030036; GO:0006915; GO:0042149; GO:0000287; GO:0043066; GO:0004674,ATP binding; actin cytoskeleton organization; apoptotic process; cellular response to glucose starvation; magnesium ion binding; negative regulation of apoptotic process; protein serine/threonine kinase activity,PF00069;,2.00E-86,CHOYP_NUAK1.1.1,,,,,,,NUAK2_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; protein phosphorylation [GO:0006468] comp121580_c3_seq1,273,41.3919,1.04848346,1,12,,8.00E-11,Q52WX2,Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1),Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1),GO:0005524; GO:0005737; GO:0004674,ATP binding; cytoplasm; protein serine/threonine kinase activity,PF00069;,,,,,,,,,SBK1_HUMAN,Homo sapiens (Human), comp121606_c0_seq1,375,48.2667,1.11161175,0,8,,7.00E-10,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp121616_c0_seq1,840,41.3095,0.42337958,0,0,,1.00E-07,Q5JHR7,"Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH))","Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH))",GO:0044205; GO:0006207; GO:0005737; GO:0004158; GO:0004589,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; cytoplasm; dihydroorotate oxidase activity; orotate reductase (NADH) activity,PF01180;,,,,,,,,,PYRDB_PYRKO,Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205] comp121616_c0_seq2,926,41.6847,0.37777158,0,0,,6.00E-24,P44606,tRNA-dihydrouridine synthase C (EC 1.-.-.-),tRNA-dihydrouridine(16) synthase (EC 1.3.1.-) (U16-specific dihydrouridine synthase) (U16-specific Dus) (tRNA-dihydrouridine synthase C),GO:0050660; GO:0017150; GO:0002943,flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF01207;,,,,,,,,,DUSC_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp121616_c0_seq3,1145,42.8821,0.40642447,0,0,,5.00E-146,Q32M08,tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 4-like),tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 4-like),GO:0050660; GO:0017150; GO:0002943,flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF01207;,8.00E-50,CHOYP_BRAFLDRAFT_129997.1.1,,,,,,,DUS4L_MOUSE,Mus musculus (Mouse), comp121616_c0_seq5,1059,42.6818,0.44311774,0,0,,5.00E-09,Q7SG01,tRNA-dihydrouridine(47) synthase [NAD(P)(+)] (EC 1.3.1.89) (tRNA-dihydrouridine synthase 3),tRNA-dihydrouridine(47) synthase [NAD(P)(+)] (EC 1.3.1.89) (tRNA-dihydrouridine synthase 3),GO:0005737; GO:0050660; GO:0046872; GO:0005634; GO:0017150; GO:0002943,cytoplasm; flavin adenine dinucleotide binding; metal ion binding; nucleus; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF01207;,,,,,,,,,DUS3_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), comp121617_c0_seq2,292,40.411,0.59073273,3,0,,6.00E-08,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,2.00E-13,CHOYP_contig_037300,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp121619_c1_seq1,395,42.0253,0.5192341,51,91,,,,,,,,,,,1.00E-14,ruditapes_c10755,,,,,,, comp121621_c0_seq2,1668,35.4317,0.61202809,968,201,,,,,,,,,3.00E-13,CHOYP_contig_043874,,,,,,,,, comp121625_c0_seq1,461,39.2625,0.11323583,14,14,,,,,,,,,4.00E-17,CHOYP_BRAFLDRAFT_67258.9.18,,,,,,,,, comp121626_c0_seq1,1209,37.2208,0.43604506,36,75,,2.00E-07,Q66KB0,Ubiquitin-conjugating enzyme E2 Z (EC 6.3.2.19) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z),Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z),GO:0005524; GO:0006915; GO:0005737; GO:0005634; GO:0004842,ATP binding; apoptotic process; cytoplasm; nucleus; ubiquitin-protein ligase activity,PF00179;,,,,,,,,,UBE2Z_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),apoptotic process [GO:0006915] comp121626_c0_seq2,869,35.7883,0.54662048,3,8,,4.00E-106,P61082,NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (NEDD8 carrier protein) (NEDD8 protein ligase) (Ubiquitin-conjugating enzyme E2 M),NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (NEDD8 carrier protein) (NEDD8 protein ligase) (Ubiquitin-conjugating enzyme E2 M),GO:0005524; GO:0019788; GO:0045116; GO:0018169; GO:0004842,ATP binding; NEDD8 ligase activity; protein neddylation; ribosomal S6-glutamic acid ligase activity; ubiquitin-protein ligase activity,PF00179;,7.00E-113,CHOYP_UBC12.1.1,,,,,,,UBC12_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464]; positive regulation of neuron apoptotic process [GO:0043525]; protein neddylation [GO:0045116] comp121631_c0_seq2,216,50.463,0.07306554,10,27,,1.00E-06,P13608,Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP),Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,PGCA_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp121634_c1_seq1,201,46.2687,1.03737395,0,31,,2.00E-08,P17972,Potassium voltage-gated channel protein Shaw (Shaw2),Potassium voltage-gated channel protein Shaw (Shaw2),GO:0005251; GO:0051260; GO:0030431; GO:0008076,delayed rectifier potassium channel activity; protein homooligomerization; sleep; voltage-gated potassium channel complex,PF02214;PF00520;,,,,,,,,,KCNAW_DROME,Drosophila melanogaster (Fruit fly),potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; sleep [GO:0030431] comp121636_c1_seq1,426,43.8967,0.54075822,23,13,,8.00E-29,A6QLK4,Transmembrane protein 8B (Protein NGX6),Transmembrane protein 8B (Protein NGX6),GO:0009986; GO:0007160; GO:0005783; GO:0016021; GO:0005739; GO:0005634; GO:0005886; GO:0040008,cell surface; cell-matrix adhesion; endoplasmic reticulum; integral to membrane; mitochondrion; nucleus; plasma membrane; regulation of growth,PF12036;,3.00E-12,CHOYP_LOC101078808.1.1,,,,,,,TMM8B_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; regulation of growth [GO:0040008] comp121639_c1_seq2,682,44.1349,0.30194583,24,11,,8.00E-68,Q6DF78,Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-),Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-),GO:0016831; GO:0019752; GO:0030170,carboxy-lyase activity; carboxylic acid metabolic process; pyridoxal phosphate binding,PF00282;,7.00E-29,CHOYP_PDXDC1.1.1,3.00E-18,ruditapes_c11609,,,,,PDXD1_XENLA,Xenopus laevis (African clawed frog),carboxylic acid metabolic process [GO:0019752] comp121642_c1_seq4,1291,36.8706,0.36603829,14,133,,2.00E-63,Q86WZ6,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121644_c0_seq1,791,41.7193,0.53495526,2,2,,4.00E-36,Q6TDP4,Kelch-like protein 17 (Actinfilin),Kelch-like protein 17 (Actinfilin),GO:0015629; GO:0030036; GO:0007420; GO:0030054; GO:0032839; GO:0043025; GO:0014069; GO:0045211; GO:0032947; GO:0016567,actin cytoskeleton; actin cytoskeleton organization; brain development; cell junction; dendrite cytoplasm; neuronal cell body; postsynaptic density; postsynaptic membrane; protein complex scaffold; protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH17_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567] comp121644_c0_seq2,924,41.8831,0.48670785,3,20,,4.00E-60,Q9P2G9,Kelch-like protein 8,Kelch-like protein 8,GO:0031463; GO:0042787,Cul3-RING ubiquitin ligase complex; protein ubiquitination involved in ubiquitin-dependent protein catabolic process,PF07707;PF00651;PF01344;,1.00E-46,CHOYP_BRAFLDRAFT_207414.1.2,,,,,,,KLHL8_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp121650_c0_seq2,821,42.1437,0.76925248,33,56,,1.00E-10,Q755Y0,Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),GO:0000139; GO:0031901; GO:0016021; GO:0018345; GO:0006612; GO:0019706; GO:0030100; GO:0010969; GO:0008270,Golgi membrane; early endosome membrane; integral to membrane; protein palmitoylation; protein targeting to membrane; protein-cysteine S-palmitoyltransferase activity; regulation of endocytosis; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; zinc ion binding,PF12796;PF01529;,,,,,,,,,AKR1_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii), comp121655_c0_seq1,792,37.7525,0.43392682,9,3,,2.00E-22,Q6P1S2,Uncharacterized protein C3orf33,Protein C3orf33 (Protein AC3-33),GO:0016788; GO:0016021; GO:0003676,"hydrolase activity, acting on ester bonds; integral to membrane; nucleic acid binding",,,,,,,,,,CC033_HUMAN,Homo sapiens (Human),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090] comp121662_c0_seq1,983,39.3693,0.64278782,37,79,,3.00E-41,Q8N4B1,Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A),Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A),GO:0005794; GO:0030136; GO:0005769; GO:0007032; GO:0005543; GO:0001881; GO:0055037; GO:0042147; GO:0005802,"Golgi apparatus; clathrin-coated vesicle; early endosome; endosome organization; phospholipid binding; receptor recycling; recycling endosome; retrograde transport, endosome to Golgi; trans-Golgi network",PF00169;,2.00E-37,CHOYP_LOC100163889.1.1,,,,,,,SESQ1_HUMAN,Homo sapiens (Human),"endosome organization [GO:0007032]; receptor recycling [GO:0001881]; retrograde transport, endosome to Golgi [GO:0042147]" comp121666_c0_seq2,1680,52.5,0.38072352,76,39,,3.00E-17,Q8NEZ4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,2.00E-16,CHOYP_LOC591084.1.2,,,,,,,MLL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121669_c0_seq1,1263,45.8432,0.36550301,7,12,,,,,,,,,,,1.00E-57,ruditapes_c31695,,,,,,, comp121669_c0_seq2,1250,45.04,0.33472233,3,0,,2.00E-14,Q9JL19,"Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Thyroid hormone receptor-binding protein)","Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Thyroid hormone receptor-binding protein)",GO:0007420; GO:0003682; GO:0007507; GO:0035097; GO:0060716; GO:0030099; GO:0045893; GO:0006974; GO:0046966; GO:0003713; GO:0005667; GO:0006351,"brain development; chromatin binding; heart development; histone methyltransferase complex; labyrinthine layer blood vessel development; myeloid cell differentiation; positive regulation of transcription, DNA-dependent; response to DNA damage stimulus; thyroid hormone receptor binding; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF13820;,5.00E-47,CHOYP_contig_045662,,,,,,,NCOA6_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; heart development [GO:0007507]; histone H3-K4 trimethylation [GO:0080182]; labyrinthine layer blood vessel development [GO:0060716]; myeloid cell differentiation [GO:0030099]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp121673_c0_seq1,396,42.4242,0.62780734,0,67,,1.00E-35,Q07075,Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),GO:0001525; GO:0002005; GO:0002003; GO:0016324; GO:0005903; GO:0016477; GO:0008283; GO:0007267; GO:0044267; GO:0031410; GO:0009897; GO:0032835; GO:0005887; GO:0005765; GO:0070006; GO:0006508; GO:0008270,angiogenesis; angiotensin catabolic process in blood; angiotensin maturation; apical plasma membrane; brush border; cell migration; cell proliferation; cell-cell signaling; cellular protein metabolic process; cytoplasmic vesicle; external side of plasma membrane; glomerulus development; integral to plasma membrane; lysosomal membrane; metalloaminopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPE_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] comp121680_c2_seq1,275,40,0.37744089,3,26,,9.00E-10,A7GS57,Methylthioribose kinase (MTR kinase) (EC 2.7.1.100),Methylthioribose kinase (MTR kinase) (EC 2.7.1.100),GO:0005524; GO:0019284; GO:0019509; GO:0046522,ATP binding; L-methionine biosynthetic process from S-adenosylmethionine; L-methionine salvage from methylthioadenosine; S-methyl-5-thioribose kinase activity,PF01636;,2.00E-12,CHOYP_LOC100889562.1.1,,,,,,,MTNK_BACCN,Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp121691_c0_seq1,383,42.0366,0.88889495,17,32,,2.00E-22,Q8BJ56,Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Desnutrin),Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Desnutrin),GO:0005829; GO:0016021; GO:0005811; GO:0010891; GO:0005886; GO:0010898; GO:0019433; GO:0004806,cytosol; integral to membrane; lipid particle; negative regulation of sequestering of triglyceride; plasma membrane; positive regulation of triglyceride catabolic process; triglyceride catabolic process; triglyceride lipase activity,PF01734;,4.00E-29,CHOYP_LOC100865198.1.1,,,,,,,PLPL2_MOUSE,Mus musculus (Mouse),lipid homeostasis [GO:0055088]; lipid particle organization [GO:0034389]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] comp121694_c0_seq1,625,40.64,0.43472334,37,20,,2.00E-08,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp121698_c1_seq2,794,45.9698,0.50590989,5,24,,1.00E-13,Q9VZZ9,Protein daughter of sevenless,Protein daughter of sevenless,GO:0005070; GO:0008595; GO:0019730; GO:0005737; GO:0005543; GO:0042461; GO:0005886; GO:0046578; GO:0045500; GO:0008293; GO:0035220,"SH3/SH2 adaptor activity; anterior/posterior axis specification, embryo; antimicrobial humoral response; cytoplasm; phospholipid binding; photoreceptor cell development; plasma membrane; regulation of Ras protein signal transduction; sevenless signaling pathway; torso signaling pathway; wing disc development",PF00169;,,,,,,,,,DOS_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior axis specification, embryo [GO:0008595]; antimicrobial humoral response [GO:0019730]; photoreceptor cell development [GO:0042461]; regulation of Ras protein signal transduction [GO:0046578]; sevenless signaling pathway [GO:0045500]; torso signaling pathway [GO:0008293]; wing disc development [GO:0035220]" comp121699_c1_seq1,349,39.8281,0.58043594,1,30,,3.00E-13,Q3UH06,Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),GO:0003677; GO:0046872; GO:0045892; GO:0016607; GO:0003700; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nuclear speck; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13912;,9.00E-18,CHOYP_RREB1.1.1,,,,,,,RREB1_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp121704_c0_seq1,515,43.4951,0.93478613,0,6,,2.00E-23,P78333,Glypican-5 [Cleaved into: Secreted glypican-5],Glypican-5 [Cleaved into: Secreted glypican-5],GO:0005796; GO:0031225; GO:0005975; GO:0030204; GO:0005615; GO:0006024; GO:0006027; GO:0005887; GO:0043202; GO:0007603; GO:0005578; GO:0001523,"Golgi lumen; anchored to membrane; carbohydrate metabolic process; chondroitin sulfate metabolic process; extracellular space; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; integral to plasma membrane; lysosomal lumen; phototransduction, visible light; proteinaceous extracellular matrix; retinoid metabolic process",PF01153;,,,,,,,,,GPC5_HUMAN,Homo sapiens (Human),glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; retinoid metabolic process [GO:0001523] comp121704_c0_seq2,547,43.6929,0.9856148,1,0,,3.00E-27,P78333,Glypican-5 [Cleaved into: Secreted glypican-5],Glypican-5 [Cleaved into: Secreted glypican-5],GO:0005796; GO:0031225; GO:0005975; GO:0030204; GO:0005615; GO:0006024; GO:0006027; GO:0005887; GO:0043202; GO:0007603; GO:0005578; GO:0001523,"Golgi lumen; anchored to membrane; carbohydrate metabolic process; chondroitin sulfate metabolic process; extracellular space; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; integral to plasma membrane; lysosomal lumen; phototransduction, visible light; proteinaceous extracellular matrix; retinoid metabolic process",PF01153;,,,,,,,,,GPC5_HUMAN,Homo sapiens (Human),glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; retinoid metabolic process [GO:0001523] comp121709_c0_seq1,523,44.9331,0.72124286,16,21,,3.00E-20,Q9P215,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,,,,,,,,,POGK_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp121716_c0_seq1,746,36.9973,0.94542173,8,97,,4.00E-09,P86734,Ependymin-related protein 1,Ependymin-related protein 1,GO:0005509; GO:0007160; GO:0005576,calcium ion binding; cell-matrix adhesion; extracellular region,PF00811;,,,,,,,,,EPDR1_HALAI,Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone),cell-matrix adhesion [GO:0007160] comp121728_c0_seq1,580,38.9655,0.51075034,18,37,,2.00E-68,P81140,"Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) (Fragment)","Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) (Fragment)",GO:0003995; GO:0050660; GO:0005759; GO:0006568,acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrial matrix; tryptophan metabolic process,PF00441;PF02770;PF02771;,5.00E-62,CHOYP_LOC580832.1.1,8.00E-82,ruditapes_c9483,,,,,GCDH_PIG,Sus scrofa (Pig),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; tryptophan metabolic process [GO:0006568] comp121741_c0_seq1,410,45.122,1.10873284,5,35,,3.00E-26,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp121743_c0_seq2,1400,41.9286,0.4323563,11,8,,2.00E-142,Q95M12,"Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1)","Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1)",GO:0045177; GO:0004197; GO:0005770; GO:0005764; GO:1901185; GO:0040015; GO:0043524; GO:0051603; GO:0032801; GO:0003014; GO:0001101,apical part of cell; cysteine-type endopeptidase activity; late endosome; lysosome; negative regulation of ERBB signaling pathway; negative regulation of multicellular organism growth; negative regulation of neuron apoptotic process; proteolysis involved in cellular protein catabolic process; receptor catabolic process; renal system process; response to acid,PF01650;,1.00E-61,CHOYP_LOC100182585.2.2,,,,,,,LGMN_BOVIN,Bos taurus (Bovine),negative regulation of ERBB signaling pathway [GO:1901185]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; vacuolar protein processing [GO:0006624] comp121748_c0_seq1,932,37.2318,0.80486635,523,1325,,6.00E-47,Q5R7L3,"39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16)","39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16)",GO:0005739; GO:0019843; GO:0005840; GO:0003735; GO:0006412,mitochondrion; rRNA binding; ribosome; structural constituent of ribosome; translation,PF00252;,,,,,,,,,RM16_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),translation [GO:0006412] comp121761_c0_seq1,696,45.2586,0.89986468,40,557,,2.00E-55,Q9UKW4,Guanine nucleotide exchange factor VAV3 (VAV-3),Guanine nucleotide exchange factor VAV3 (VAV-3),GO:0050853; GO:0038095; GO:0038096; GO:0005096; GO:0030676; GO:0005070; GO:0001525; GO:0097190; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0007229; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0030890; GO:0043065; GO:0045785; GO:0043552; GO:0035023; GO:0051056; GO:0006974; GO:0042493; GO:0007264; GO:0006906,B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; SH3/SH2 adaptor activity; angiogenesis; apoptotic signaling pathway; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; integrin-mediated signaling pathway; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of B cell proliferation; positive regulation of apoptotic process; positive regulation of cell adhesion; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; response to DNA damage stimulus; response to drug; small GTPase mediated signal transduction; vesicle fusion,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,2.00E-36,CHOYP_LOC733982.1.1,,,,,,,VAV3_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell adhesion [GO:0045785]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to drug [GO:0042493]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle fusion [GO:0006906] comp121763_c0_seq2,566,49.2933,0.32562491,0,3,,,,,,,,,3.00E-76,CHOYP_ASCC3.1.1,,,,,,,,, comp121763_c1_seq1,395,44.0506,0.27619092,10,29,,1.00E-12,Q5JGV6,Putative ski2-type helicase (EC 3.6.4.-) [Cleaved into: Endonuclease PI-PkoHel (EC 3.1.-.-) (Pko Hel intein)],ATP-dependent DNA helicase Hel308 (EC 3.6.4.12) (ATP-dependent Holliday junction unwindase Hjm) [Cleaved into: Endonuclease PI-PkoHel (EC 3.1.-.-) (Pko Hel intein)],GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0004519; GO:0016539; GO:0006314; GO:0090305,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; endonuclease activity; intein-mediated protein splicing; intron homing; nucleic acid phosphodiester bond hydrolysis,PF00270;PF14528;,,,,,,,,,HELS_PYRKO,Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)),DNA repair [GO:0006281]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314] comp121763_c3_seq1,743,46.1642,0.45579008,20,46,,3.00E-142,E7F8F4,Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0006307; GO:0008283; GO:0005737; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA dealkylation involved in DNA repair; cell proliferation; cytoplasm; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00270;PF00271;PF02889;,5.00E-145,CHOYP_ASCC3.1.1,,,,,,,ASCC3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121773_c0_seq1,834,42.2062,0.53940646,27,117,,2.00E-12,A2A7Y5,Migration and invasion-inhibitory protein (Invasion-inhibitory protein 45) (IIp45),Migration and invasion-inhibitory protein (Invasion-inhibitory protein 45) (IIp45),,,PF15734;,3.00E-21,CHOYP_MIIP.1.1,,,,,,,MIIP_MOUSE,Mus musculus (Mouse),negative regulation of cell migration [GO:0030336]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972] comp121774_c0_seq1,318,47.4843,0.35484222,5,7,,,,,,,,,,,3.00E-33,ruditapes_c21735,,,,,,, comp121774_c1_seq1,579,44.0415,0.46762729,6,45,,,,,,,,,6.00E-16,CHOYP_BRAFLDRAFT_284972.1.1,,,,,,,,, comp121777_c0_seq1,340,47.0588,0.63978039,14,30,,4.00E-16,Q5U3Y0,Kelch domain-containing protein 10,Kelch domain-containing protein 10,GO:0005737; GO:0005634,cytoplasm; nucleus,PF01344;,,,,,,,,,KLD10_RAT,Rattus norvegicus (Rat), comp121777_c1_seq1,309,44.0129,0.89956299,4,9,,7.00E-14,Q28DE7,Kelch domain-containing protein 10,Kelch domain-containing protein 10,GO:0005737; GO:0005634,cytoplasm; nucleus,PF01344;,,,,,,,,,KLD10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp121786_c0_seq1,1019,30.6183,0.33552664,31,315,,,,,,,,,,,5.00E-12,ruditapes_c4529,,,,,,, comp121787_c0_seq1,1926,43.3541,0.58907246,9,6,,4.00E-21,Q8N2C3,DEP domain-containing protein 4,DEP domain-containing protein 4,GO:0035556,intracellular signal transduction,PF00610;,5.00E-17,CHOYP_BRAFLDRAFT_214790.1.1,,,,,,,DEPD4_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp121787_c0_seq3,1652,42.7361,0.58792834,4,3,,1.00E-35,Q91WS7,DEP domain-containing protein 7 (Protein TR2/D15),DEP domain-containing protein 7 (Protein TR2/D15),GO:0035556,intracellular signal transduction,PF00610;,,,,,,,,,DEPD7_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556] comp121788_c0_seq1,342,45.3216,0.31182085,12,30,,8.00E-64,Q8QG61,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0005737; GO:0000166; GO:0005634; GO:0009881; GO:0018298; GO:0006355; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; cytoplasm; nucleotide binding; nucleus; photoreceptor activity; protein-chromophore linkage; regulation of transcription, DNA-dependent; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,7.00E-57,CHOYP_CRY1.2.2,,,,,,,CRY1_CHICK,Gallus gallus (Chicken),"protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp121793_c0_seq1,427,40.7494,0.45972325,0,0,,1.00E-08,A2BDA5,DDB1- and CUL4-associated factor 15,DDB1- and CUL4-associated factor 15,GO:0016567,protein ubiquitination,PF14939;,,,,,,,,,DCA15_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567] comp121793_c0_seq2,1965,42.1374,0.43618753,63,98,,6.00E-21,A2BDA5,DDB1- and CUL4-associated factor 15,DDB1- and CUL4-associated factor 15,GO:0016567,protein ubiquitination,PF14939;,1.00E-11,CHOYP_DCA15.1.1,,,,,,,DCA15_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567] comp121796_c0_seq1,493,47.0588,0.62429635,16,28,,1.00E-21,Q08DV6,Ankyrin repeat and SOCS box protein 3 (ASB-3),Ankyrin repeat and SOCS box protein 3 (ASB-3),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB3_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556] comp121796_c1_seq1,233,41.6309,0.39898433,6,10,,3.00E-06,Q8R3P9,Ankyrin repeat domain-containing protein 32 (BRCT domain-containing protein 1),SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Protein BRCTx),GO:0005813; GO:0005634,centrosome; nucleus,PF12796;PF16770;,,,,,,,,,ANR32_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166] comp121801_c0_seq1,205,44.3902,1.40139389,1,1,,2.00E-19,Q24814,Rho-related protein racA,Rho-related protein racA,GO:0005525; GO:0005622; GO:0005886; GO:0007264,GTP binding; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RACA_ENTHI,Entamoeba histolytica,small GTPase mediated signal transduction [GO:0007264] comp121801_c2_seq1,604,39.0728,0.78232973,9,74,,5.00E-27,Q9EQT3,Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1),Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1),GO:0000082; GO:0005525; GO:0003924; GO:0000139; GO:0016601; GO:0030036; GO:0042995; GO:0005925; GO:0046872; GO:0005886; GO:0002102; GO:0008360,G1/S transition of mitotic cell cycle; GTP binding; GTPase activity; Golgi membrane; Rac protein signal transduction; actin cytoskeleton organization; cell projection; focal adhesion; metal ion binding; plasma membrane; podosome; regulation of cell shape,PF00071;,5.00E-24,CHOYP_LOC100368648.1.1,,,,,,,RHOU_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of protein targeting to mitochondrion [GO:1903955]; Rac protein signal transduction [GO:0016601]; regulation of cell shape [GO:0008360] comp121820_c0_seq1,1937,36.4997,0.46197487,2511,4656,,3.00E-154,P07607,Thymidylate synthase (TS) (TSase) (EC 2.1.1.45),Thymidylate synthase (TS) (TSase) (EC 2.1.1.45),GO:0007568; GO:0051216; GO:0007623; GO:0048037; GO:0006231; GO:0006235; GO:0046078; GO:0048589; GO:0008144; GO:0005542; GO:0019088; GO:0060574; GO:0003729; GO:0005743; GO:0005759; GO:0005730; GO:0000166; GO:0005634; GO:0031100; GO:0005976; GO:0034097; GO:0042493; GO:0045471; GO:0051593; GO:0051384; GO:0046683; GO:0032570; GO:0009636; GO:0033189; GO:0046653; GO:0004799; GO:0019860,aging; cartilage development; circadian rhythm; cofactor binding; dTMP biosynthetic process; dTTP biosynthetic process; dUMP metabolic process; developmental growth; drug binding; folic acid binding; immortalization of host cell by virus; intestinal epithelial cell maturation; mRNA binding; mitochondrial inner membrane; mitochondrial matrix; nucleolus; nucleotide binding; nucleus; organ regeneration; polysaccharide metabolic process; response to cytokine stimulus; response to drug; response to ethanol; response to folic acid; response to glucocorticoid stimulus; response to organophosphorus; response to progesterone stimulus; response to toxic substance; response to vitamin A; tetrahydrofolate metabolic process; thymidylate synthase activity; uracil metabolic process,PF00303;,1.00E-131,CHOYP_LOC100013725.1.2,,,,,,,TYSY_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; organ regeneration [GO:0031100]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860] comp121824_c1_seq1,2681,41.1414,0.86225824,94,271,,3.00E-09,O95140,Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2),Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2),GO:0005525; GO:0003924; GO:0001825; GO:0007596; GO:0048593; GO:0005829; GO:0016021; GO:0031306; GO:0015630; GO:0008053; GO:0007006; GO:0051646; GO:0046580; GO:0048662; GO:0006626,GTP binding; GTPase activity; blastocyst formation; blood coagulation; camera-type eye morphogenesis; cytosol; integral to membrane; intrinsic to mitochondrial outer membrane; microtubule cytoskeleton; mitochondrial fusion; mitochondrial membrane organization; mitochondrion localization; negative regulation of Ras protein signal transduction; negative regulation of smooth muscle cell proliferation; protein targeting to mitochondrion,PF00350;PF04799;,,,,,,,,,MFN2_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; blastocyst formation [GO:0001825]; blood coagulation [GO:0007596]; camera-type eye morphogenesis [GO:0048593]; macroautophagy [GO:0016236]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; mitochondrion localization [GO:0051646]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of smooth muscle cell proliferation [GO:0048662]; protein localization to pre-autophagosomal structure [GO:0034497]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986] comp121827_c0_seq1,1686,42.4674,0.70824683,0,750,female,,,,,,,,3.00E-25,CHOYP_LOC100744767.1.2,,,,,,,,, comp121827_c0_seq2,1671,42.8486,0.68637135,2036,4014,,9.00E-28,Q27294,RNA-binding protein cabeza (P19) (Sarcoma-associated RNA-binding fly homolog),RNA-binding protein cabeza (P19) (Sarcoma-associated RNA-binding fly homolog),GO:0008344; GO:0071013; GO:0048749; GO:0008345; GO:0003729; GO:0000398; GO:0005654; GO:0000166; GO:0008270,"adult locomotory behavior; catalytic step 2 spliceosome; compound eye development; larval locomotory behavior; mRNA binding; mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding; zinc ion binding",PF00076;PF00641;,7.00E-59,CHOYP_LOC100744767.2.2,3.00E-11,ruditapes2_c983,,,,,CAZ_DROME,Drosophila melanogaster (Fruit fly),"adult locomotory behavior [GO:0008344]; compound eye development [GO:0048749]; larval locomotory behavior [GO:0008345]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; synaptic growth at neuromuscular junction [GO:0051124]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp121835_c0_seq2,1049,37.5596,0.35263149,0,0,,,,,,,,,5.00E-14,CHOYP_LOC100900174.1.1,,,,,,,,, comp121836_c0_seq3,327,45.5657,0.29581806,13,11,,1.00E-23,Q8VI59,Pecanex-like protein 3,Pecanex-like protein 3 (Pecanex homolog protein 3),GO:0016021,integral to membrane,PF05041;,2.00E-20,CHOYP_PCX1.1.1,,,,,,,PCX3_MOUSE,Mus musculus (Mouse), comp121849_c0_seq1,421,37.0546,0.85253006,12,42,,2.00E-07,Q9HAZ2,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;PF13912;,,,,,,,,,PRD16_HUMAN,Homo sapiens (Human),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp121852_c1_seq2,961,37.7732,0.3262428,49,144,,4.00E-31,Q8WXD5,Gem-associated protein 6 (Gemin-6) (SIP2),Gem-associated protein 6 (Gemin-6) (SIP2),GO:0097504; GO:0005829; GO:0034660; GO:0016604; GO:0005681; GO:0000245; GO:0000387,Gemini of coiled bodies; cytosol; ncRNA metabolic process; nuclear body; spliceosomal complex; spliceosomal complex assembly; spliceosomal snRNP assembly,PF06372;,6.00E-13,CHOYP_BRAFLDRAFT_60087.1.1,,,,,,,GEMI6_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]" comp121856_c0_seq1,625,32.16,0.71136546,850,2141,,3.00E-22,P82921,"28S ribosomal protein S21, mitochondrial (MRP-S21) (S21mt)","28S ribosomal protein S21, mitochondrial (MRP-S21) (S21mt)",GO:0005763; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; structural constituent of ribosome; translation,PF01165;,,,8.00E-26,ruditapes2_c251,,,,,RT21_HUMAN,Homo sapiens (Human),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412] comp121860_c0_seq1,815,40.9816,1.00086731,80,557,,3.00E-14,Q62210,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Inhibitor of apoptosis protein 2) (IAP-2) (mIAP-2) (mIAP2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2),GO:0035631; GO:0006915; GO:0005737; GO:0009898; GO:0070266; GO:0060546; GO:1902443; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0070936; GO:0070534; GO:0042981; GO:0051726; GO:2000377; GO:0006355; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; apoptotic process; cytoplasm; internal side of plasma membrane; necroptosis; negative regulation of necroptosis; negative regulation of ripoptosome assembly involved in necroptosis; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein K63-linked ubiquitination; regulation of apoptotic process; regulation of cell cycle; regulation of reactive oxygen species metabolic process; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_MOUSE,Mus musculus (Mouse),"inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp121863_c0_seq1,869,38.7802,0.4712899,108,113,,8.00E-54,Q8VCE1,DnaJ homolog subfamily C member 28,DnaJ homolog subfamily C member 28,,,PF00226;PF09350;,,,,,,,,,DJC28_MOUSE,Mus musculus (Mouse),"Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp121863_c1_seq1,221,41.1765,0.32647727,8,5,,2.00E-09,Q83CJ2,Curved DNA-binding protein,Curved DNA-binding protein,GO:0003677; GO:0003681; GO:0005737; GO:0009295; GO:0006457,DNA binding; bent DNA binding; cytoplasm; nucleoid; protein folding,PF00226;PF01556;,,,,,,,,,CBPA_COXBU,Coxiella burnetii (strain RSA 493 / Nine Mile phase I),protein folding [GO:0006457] comp121866_c0_seq1,204,42.1569,0.2247861,3,49,,4.00E-24,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp121872_c0_seq1,880,43.0682,0.45584743,19,88,,3.00E-56,Q4L235,Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (Aminoadipate-semialdehyde dehydrogenase) (Protein NRPS998),Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (Aminoadipate-semialdehyde dehydrogenase) (Protein NRPS998),GO:0005524; GO:0016878; GO:0006631,ATP binding; acid-thiol ligase activity; fatty acid metabolic process,PF00501;PF00550;PF13360;PF13570;,,,,,,,,,ACSF4_HUMAN,Homo sapiens (Human),fatty acid metabolic process [GO:0006631] comp121882_c1_seq1,639,41.784,0.47096232,0,0,,5.00E-42,Q6PB44,Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48),Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48),GO:0005929; GO:0060271; GO:0016023; GO:0005769; GO:0005932; GO:0005634; GO:0035335; GO:0015031; GO:0004725; GO:0043162,cilium; cilium morphogenesis; cytoplasmic membrane-bounded vesicle; early endosome; microtubule basal body; nucleus; peptidyl-tyrosine dephosphorylation; protein transport; protein tyrosine phosphatase activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF13949;PF03097;PF00102;,7.00E-16,CHOYP_PTPN23.1.1,,,,,,,PTN23_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp121885_c1_seq1,544,44.6691,0.38483395,12,25,,3.00E-17,Q2T9J0,"Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]","Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]",GO:0005777; GO:0051260; GO:0016485; GO:0006508; GO:0031998; GO:0004252,peroxisome; protein homooligomerization; protein processing; proteolysis; regulation of fatty acid beta-oxidation; serine-type endopeptidase activity,,,,,,,,,,TYSD1_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998] comp121888_c0_seq2,736,43.2065,0.52884291,14,20,,2.00E-07,P87231,Crossover junction endonuclease mus81 (EC 3.1.22.-),Crossover junction endonuclease mus81 (EC 3.1.22.-),GO:0003677; GO:0048476; GO:0008821; GO:0031573; GO:0000711; GO:0000709; GO:0046872; GO:0005739; GO:0033314; GO:0005634; GO:0006301; GO:0031297,DNA binding; Holliday junction resolvase complex; crossover junction endodeoxyribonuclease activity; intra-S DNA damage checkpoint; meiotic DNA repair synthesis; meiotic joint molecule formation; metal ion binding; mitochondrion; mitotic DNA replication checkpoint; nucleus; postreplication repair; replication fork processing,PF02732;,,,,,,,,,MUS81_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; intra-S DNA damage checkpoint [GO:0031573]; meiotic joint molecule formation [GO:0000709]; mitotic DNA replication checkpoint [GO:0033314]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]" comp121897_c0_seq1,576,41.1458,0.28878966,8,81,,,,,,,,,1.00E-12,CHOYP_ANKZF1.1.1,,,,,,,,, comp121901_c0_seq1,278,34.8921,0.72910351,489,850,,,,,,,,,2.00E-17,CHOYP_TBA1.8.9,,,,,,,,, comp121901_c0_seq2,307,34.5277,0.67323119,521,2231,,,,,,,,,3.00E-17,CHOYP_TBA1.8.9,5.00E-18,ruditapes_s40373,,,,,,, comp121902_c0_seq2,397,43.3249,0.2744088,36,0,,8.00E-23,Q7Z443,Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3),Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3),GO:0030246; GO:0006812; GO:0071468; GO:0001581; GO:0016021; GO:0007218,carbohydrate binding; cation transport; cellular response to acidity; detection of chemical stimulus involved in sensory perception of sour taste; integral to membrane; neuropeptide signaling pathway,PF01825;PF00059;PF08016;PF01477;,,,,,,,,,PK1L3_HUMAN,Homo sapiens (Human),cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; kidney development [GO:0001822]; sensory perception of sour taste [GO:0050915] comp121902_c1_seq1,485,44.5361,0.50276076,62,8,,2.00E-29,Q7Z442,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005509; GO:0030246; GO:0016021; GO:0006811; GO:0007218,calcium ion binding; carbohydrate binding; integral to membrane; ion transport; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982] comp121905_c0_seq1,967,46.2254,0.50384423,51,50,,6.00E-18,Q58DZ6,Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,5.00E-14,CHOYP_ZNF76.1.1,,,,,,,ZN143_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121905_c1_seq1,263,44.1065,0.72373876,7,8,,4.00E-20,O70230,Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor) (mStaf),Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor) (mStaf),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN143_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121908_c0_seq2,896,43.0804,0.34928979,3,9,,4.00E-83,Q8TC12,Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1),Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short chain dehydrogenase/reductase family 7C member 1),GO:0052650; GO:0005789; GO:0016021; GO:0007603; GO:0042574; GO:0004745,"NADP-retinol dehydrogenase activity; endoplasmic reticulum membrane; integral to membrane; phototransduction, visible light; retinal metabolic process; retinol dehydrogenase activity",PF00106;,,,,,,,,,RDH11_HUMAN,Homo sapiens (Human),adaptation of rhodopsin mediated signaling [GO:0016062]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] comp121908_c0_seq3,726,42.6997,0.34035645,0,0,,7.00E-08,Q9P324,Uncharacterized oxidoreductase C977.08/C1348.09 (EC 1.-.-.-),,GO:0005829; GO:0005634; GO:0016491,cytosol; nucleus; oxidoreductase activity,,,,,,,,,,YI78_SCHPO,, comp121908_c0_seq4,376,43.0851,0.38786283,4,11,,1.00E-07,O54939,Testosterone 17-beta-dehydrogenase 3 (EC 1.1.1.64) (17-beta-hydroxysteroid dehydrogenase type 3) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase),Testosterone 17-beta-dehydrogenase 3 (EC 1.1.1.64) (17-beta-hydroxysteroid dehydrogenase type 3) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase),GO:0033327; GO:0018879; GO:0071236; GO:0071371; GO:0004303; GO:0021766; GO:0017143; GO:0043231; GO:0006082; GO:0018958; GO:0033591; GO:0014823; GO:0046685; GO:0046686; GO:0051412; GO:0043627; GO:0045471; GO:0070542; GO:0060992; GO:0009635; GO:0010288; GO:0033197; GO:0006694; GO:0047045; GO:0061370; GO:0047035,Leydig cell differentiation; biphenyl metabolic process; cellular response to antibiotic; cellular response to gonadotropin stimulus; estradiol 17-beta-dehydrogenase activity; hippocampus development; insecticide metabolic process; intracellular membrane-bounded organelle; organic acid metabolic process; phenol-containing compound metabolic process; response to L-ascorbic acid; response to activity; response to arsenic-containing substance; response to cadmium ion; response to corticosterone stimulus; response to estrogen stimulus; response to ethanol; response to fatty acid; response to fungicide; response to herbicide; response to lead ion; response to vitamin E; steroid biosynthetic process; testosterone 17-beta-dehydrogenase (NADP+) activity; testosterone biosynthetic process; testosterone dehydrogenase (NAD+) activity,PF00106;,7.00E-13,CHOYP_TRIADDRAFT_18543.1.2,,,,,,,DHB3_RAT,Rattus norvegicus (Rat),biphenyl metabolic process [GO:0018879]; cellular response to antibiotic [GO:0071236]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to hormone stimulus [GO:0032870]; hippocampus development [GO:0021766]; insecticide metabolic process [GO:0017143]; Leydig cell differentiation [GO:0033327]; male genitalia development [GO:0030539]; organic acid metabolic process [GO:0006082]; phenol-containing compound metabolic process [GO:0018958]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to fungicide [GO:0060992]; response to herbicide [GO:0009635]; response to insecticide [GO:0017085]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to metal ion [GO:0010038]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to steroid hormone [GO:0048545]; response to vitamin E [GO:0033197]; steroid biosynthetic process [GO:0006694]; testosterone biosynthetic process [GO:0061370] comp121914_c0_seq1,259,45.5598,0.16471579,64,0,,,,,,,,,5.00E-13,CHOYP_LOC100929680.2.2,,,,,,,,, comp121916_c0_seq1,819,34.9206,0.84312699,18,277,,3.00E-11,Q8QGW7,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome),Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome),GO:0005125; GO:0005737; GO:0006355; GO:0006351,"cytokine activity; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10601;,4.00E-14,CHOYP_LOC100369143.2.2,3.00E-19,ruditapes2_c100,,,,,LITAF_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp121921_c1_seq1,942,43.4183,0.54972129,7,27,,1.00E-48,Q5ZKZ4,DnaJ homolog subfamily C member 16,DnaJ homolog subfamily C member 16,GO:0045454; GO:0016021,cell redox homeostasis; integral to membrane,PF00226;PF00085;,,,,,,,,,DJC16_CHICK,Gallus gallus (Chicken),cell redox homeostasis [GO:0045454] comp121921_c2_seq1,215,37.6744,0.79608602,7,0,,3.00E-16,Q6NRT6,DnaJ homolog subfamily C member 10 (EC 1.8.4.-),DnaJ homolog subfamily C member 10 (EC 1.8.4.-),GO:0030433; GO:0045454; GO:0005788; GO:0006662; GO:0016671; GO:0015035; GO:0034975,"ER-associated protein catabolic process; cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; protein disulfide oxidoreductase activity; protein folding in endoplasmic reticulum",PF00226;PF00085;,8.00E-16,CHOYP_LOC100863952.1.1,,,,,,,DJC10_XENLA,Xenopus laevis (African clawed frog),cell redox homeostasis [GO:0045454]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein folding in endoplasmic reticulum [GO:0034975] comp121924_c0_seq1,244,40.9836,0.79193249,4,10,,1.00E-09,Q99PE7,ATP-binding cassette sub-family G member 5 (Sterolin-1),ATP-binding cassette sub-family G member 5 (Sterolin-1),GO:0005524; GO:0043190; GO:0016887; GO:0016324; GO:0033344; GO:0042632; GO:0017127; GO:0007588; GO:0016021; GO:0045796; GO:0010949; GO:0030300; GO:0042493; GO:0010212; GO:0007584,ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity; apical plasma membrane; cholesterol efflux; cholesterol homeostasis; cholesterol transporter activity; excretion; integral to membrane; negative regulation of intestinal cholesterol absorption; negative regulation of intestinal phytosterol absorption; regulation of intestinal cholesterol absorption; response to drug; response to ionizing radiation; response to nutrient,PF01061;PF00005;,,,,,,,,,ABCG5_RAT,Rattus norvegicus (Rat),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol transport [GO:0030301]; excretion [GO:0007588]; negative regulation of intestinal cholesterol absorption [GO:0045796]; negative regulation of intestinal phytosterol absorption [GO:0010949]; regulation of intestinal cholesterol absorption [GO:0030300]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212]; response to nutrient [GO:0007584]; sterol transport [GO:0015918] comp121929_c1_seq1,1071,46.7787,0.37728396,3,0,,1.00E-59,P42858,Huntingtin (Huntington disease protein) (HD protein),Huntingtin (Huntington disease protein) (HD protein),GO:0006888; GO:0005794; GO:0007030; GO:0051938; GO:0009952; GO:0005776; GO:0030424; GO:0008088; GO:0048487; GO:0007569; GO:0000052; GO:0030659; GO:0005829; GO:0030425; GO:0008340; GO:0050809; GO:0007212; GO:0045505; GO:0005783; GO:0007029; GO:0016197; GO:0000132; GO:0042445; GO:0016234; GO:0030073; GO:0055072; GO:0019244; GO:0005770; GO:0007626; GO:2001237; GO:0043524; GO:0021990; GO:0051402; GO:0048666; GO:0005634; GO:0021988; GO:0048513; GO:0048341; GO:0043234; GO:0006606; GO:0019805; GO:0046902; GO:0051881; GO:0046825; GO:0034047; GO:0048167; GO:0051592; GO:0006890; GO:0035176; GO:0007283; GO:0021756; GO:0008134; GO:0000050; GO:0047496; GO:0008542,"ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi organization; L-glutamate import; anterior/posterior pattern specification; autophagic vacuole; axon; axon cargo transport; beta-tubulin binding; cell aging; citrulline metabolic process; cytoplasmic vesicle membrane; cytosol; dendrite; determination of adult lifespan; diazepam binding; dopamine receptor signaling pathway; dynein intermediate chain binding; endoplasmic reticulum; endoplasmic reticulum organization; endosomal transport; establishment of mitotic spindle orientation; hormone metabolic process; inclusion body; insulin secretion; iron ion homeostasis; lactate biosynthetic process from pyruvate; late endosome; locomotory behavior; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of neuron apoptotic process; neural plate formation; neuron apoptotic process; neuron development; nucleus; olfactory lobe development; organ development; paraxial mesoderm formation; protein complex; protein import into nucleus; quinolinate biosynthetic process; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; regulation of protein export from nucleus; regulation of protein phosphatase type 2A activity; regulation of synaptic plasticity; response to calcium ion; retrograde vesicle-mediated transport, Golgi to ER; social behavior; spermatogenesis; striatum development; transcription factor binding; urea cycle; vesicle transport along microtubule; visual learning",PF12372;,3.00E-29,CHOYP_HD.1.1,,,,,,,HD_HUMAN,Homo sapiens (Human),"animal organ development [GO:0048513]; apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; mRNA transport [GO:0051028]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; regulation of protein phosphatase type 2A activity [GO:0034047]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]" comp121929_c1_seq3,1180,46.7797,0.35778477,5,17,,,,,,,,,1.00E-28,CHOYP_HTT.1.1,7.00E-55,ruditapes_c20522,,,,,,, comp121934_c0_seq1,1198,39.3155,0.45474115,78,43,,4.00E-89,Q5ZKY4,Inhibitor of growth protein 4 (p29ING4),Inhibitor of growth protein 4 (p29ING4),GO:0006978; GO:0006260; GO:0006915; GO:0007050; GO:0043966; GO:0043983; GO:0043981; GO:0043982; GO:0000123; GO:0008285; GO:0045926; GO:0045892; GO:0043065; GO:0003713; GO:0008270,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; DNA replication; apoptotic process; cell cycle arrest; histone H3 acetylation; histone H4-K12 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex; negative regulation of cell proliferation; negative regulation of growth; negative regulation of transcription, DNA-dependent; positive regulation of apoptotic process; transcription coactivator activity; zinc ion binding",PF12998;,9.00E-88,CHOYP_ING5.1.1,1.00E-96,ruditapes2_c1124,,,,,ING4_CHICK,Gallus gallus (Chicken),"apoptotic process [GO:0006915]; cell cycle arrest [GO:0007050]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA replication [GO:0006260]; histone H3 acetylation [GO:0043966]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of cell proliferation [GO:0008285]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]" comp121934_c0_seq2,328,42.0732,0.30176846,1,19,,,,,,,,,2.00E-25,CHOYP_ING5.1.1,,,,,,,,, comp121935_c1_seq1,347,43.804,0.54564913,10,19,,4.00E-19,Q5F3S2,Pleckstrin homology domain-containing family B member 2 (PH domain-containing family B member 2) (Evectin-2),Pleckstrin homology domain-containing family B member 2 (PH domain-containing family B member 2) (Evectin-2),GO:0005543; GO:0055038,phospholipid binding; recycling endosome membrane,PF00169;,,,,,,,,,PKHB2_CHICK,Gallus gallus (Chicken),regulation of cell differentiation [GO:0045595] comp121937_c0_seq1,434,44.47,0.63312024,1,34,,7.00E-41,Q924Z6,Exportin-6 (Exp6) (Ran-binding protein 20),Exportin-6 (Exp6) (Ran-binding protein 20),GO:0005737; GO:0005634; GO:0006611,cytoplasm; nucleus; protein export from nucleus,PF03810;PF08389;,1.00E-16,CHOYP_XPO6.1.1,,,,,,,XPO6_MOUSE,Mus musculus (Mouse),protein export from nucleus [GO:0006611] comp121941_c0_seq2,815,39.6319,0.69743695,18,100,,1.00E-37,P50226,Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2),Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2),GO:0050427; GO:0009309; GO:0004062; GO:0006584; GO:0005829; GO:0047894; GO:0018958; GO:0008202; GO:0051923; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine biosynthetic process; aryl sulfotransferase activity; catecholamine metabolic process; cytosol; flavonol 3-sulfotransferase activity; phenol-containing compound metabolic process; steroid metabolic process; sulfation; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1A2_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine biosynthetic process [GO:0009309]; catecholamine metabolic process [GO:0006584]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805] comp121947_c0_seq1,516,43.2171,0.54306927,0,3,,,,,,,,,2.00E-66,CHOYP_LOC100016889.1.1,,,,,,,,, comp121947_c0_seq2,543,43.2781,0.51380587,5,0,,1.00E-51,Q8N2U9,PQ-loop repeat-containing protein 1,PQ-loop repeat-containing protein 1,GO:0016021,integral to membrane,PF04193;,,,,,,,,,PQLC1_HUMAN,Homo sapiens (Human), comp121951_c0_seq1,695,44.4604,0.41010186,25,56,,2.00E-15,P36576,Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (Fragment),Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (Fragment),GO:0009968; GO:0007165; GO:0007601,negative regulation of signal transduction; signal transduction; visual perception,,8.00E-92,CHOYP_ARRB.1.2,,,,,,,ARRC_RAT,Rattus norvegicus (Rat),negative regulation of signal transduction [GO:0009968]; signal transduction [GO:0007165]; visual perception [GO:0007601] comp121951_c0_seq2,625,49.28,0.50154039,16,43,,2.00E-90,P49407,Beta-arrestin-1 (Arrestin beta-1),Beta-arrestin-1 (Arrestin beta-1),GO:0002031; GO:0005096; GO:0000139; GO:0007219; GO:0000187; GO:0016323; GO:0000785; GO:0005905; GO:0043027; GO:0030659; GO:0005829; GO:0043197; GO:0004857; GO:0042699; GO:0005765; GO:0034260; GO:0032088; GO:0032715; GO:0032717; GO:0001933; GO:0031397; GO:0005634; GO:0007602; GO:0005886; GO:0030168; GO:0070374; GO:0035025; GO:0090240; GO:0035774; GO:0033138; GO:0032092; GO:0001934; GO:0031398; GO:0002092; GO:0034393; GO:0045944; GO:0006892; GO:0014069; GO:0045211; GO:0043161; GO:0015031; GO:0016567; GO:0031143; GO:0043149; GO:0006366; GO:0044212,G-protein coupled receptor internalization; GTPase activator activity; Golgi membrane; Notch signaling pathway; activation of MAPK activity; basolateral plasma membrane; chromatin; coated pit; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasmic vesicle membrane; cytosol; dendritic spine; enzyme inhibitor activity; follicle-stimulating hormone signaling pathway; lysosomal membrane; negative regulation of GTPase activity; negative regulation of NF-kappaB transcription factor activity; negative regulation of interleukin-6 production; negative regulation of interleukin-8 production; negative regulation of protein phosphorylation; negative regulation of protein ubiquitination; nucleus; phototransduction; plasma membrane; platelet activation; positive regulation of ERK1 and ERK2 cascade; positive regulation of Rho protein signal transduction; positive regulation of histone H4 acetylation; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein binding; positive regulation of protein phosphorylation; positive regulation of protein ubiquitination; positive regulation of receptor internalization; positive regulation of smooth muscle cell apoptotic process; positive regulation of transcription from RNA polymerase II promoter; post-Golgi vesicle-mediated transport; postsynaptic density; postsynaptic membrane; proteasomal ubiquitin-dependent protein catabolic process; protein transport; protein ubiquitination; pseudopodium; stress fiber assembly; transcription from RNA polymerase II promoter; transcription regulatory region DNA binding,PF02752;PF00339;,4.00E-38,CHOYP_ARRB.2.2,,,,,,,ARRB1_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; follicle-stimulating hormone signaling pathway [GO:0042699]; G-protein coupled receptor internalization [GO:0002031]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of GTPase activity [GO:0034260]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein ubiquitination [GO:0031397]; phototransduction [GO:0007602]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of receptor internalization [GO:0002092]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; response to antidepressant [GO:0036276]; stress fiber assembly [GO:0043149]; transcription from RNA polymerase II promoter [GO:0006366] comp121955_c1_seq1,632,41.6139,0.98849293,6,97,,4.00E-37,Q5E9S3,Transcription factor 21 (TCF-21),Transcription factor 21 (TCF-21),GO:0070888; GO:0001078; GO:0001077; GO:0060008; GO:0001658; GO:0014707; GO:0060435; GO:0060539; GO:0048557; GO:0048732; GO:0048286; GO:0060425; GO:0060426; GO:0072277; GO:0072162; GO:0060766; GO:0005634; GO:0060021; GO:0007530; GO:0048536,E-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; Sertoli cell differentiation; branching involved in ureteric bud morphogenesis; branchiomeric skeletal muscle development; bronchiole development; diaphragm development; embryonic digestive tract morphogenesis; gland development; lung alveolus development; lung morphogenesis; lung vasculature development; metanephric glomerular capillary formation; metanephric mesenchymal cell differentiation; negative regulation of androgen receptor signaling pathway; nucleus; palate development; sex determination; spleen development,PF00010;,3.00E-26,CHOYP_TCF21.1.1,,,,,,,TCF21_BOVIN,Bos taurus (Bovine),branching involved in ureteric bud morphogenesis [GO:0001658]; branchiomeric skeletal muscle development [GO:0014707]; bronchiole development [GO:0060435]; diaphragm development [GO:0060539]; embryonic digestive tract morphogenesis [GO:0048557]; epithelial cell differentiation [GO:0030855]; gland development [GO:0048732]; glomerulus development [GO:0032835]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; lung vasculature development [GO:0060426]; metanephric glomerular capillary formation [GO:0072277]; metanephric mesenchymal cell differentiation [GO:0072162]; morphogenesis of a branching structure [GO:0001763]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; palate development [GO:0060021]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; reproductive structure development [GO:0048608]; respiratory system development [GO:0060541]; Sertoli cell differentiation [GO:0060008]; sex determination [GO:0007530]; spleen development [GO:0048536]; ureteric bud development [GO:0001657]; vasculature development [GO:0001944] comp121956_c0_seq1,868,32.7189,0.56575596,866,2248,,5.00E-19,Q9VZD5,"Probable 28S ribosomal protein S6, mitochondrial (MRP-S6) (S6mt)","Probable 28S ribosomal protein S6, mitochondrial (MRP-S6) (S6mt)",GO:0005763; GO:0019843; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; rRNA binding; structural constituent of ribosome; translation,PF01250;,,,4.00E-25,ruditapes2_c287,,,,,RT06_DROME,Drosophila melanogaster (Fruit fly),mitochondrial translation [GO:0032543]; translation [GO:0006412] comp121964_c1_seq1,941,46.9713,0.36648484,63,13,,3.00E-81,Q5RHR6,Protein broad-minded (TBC1 domain family member 32),Protein broad-minded (TBC1 domain family member 32),GO:0005097; GO:0005929; GO:0035083; GO:0005737; GO:0007275; GO:0032851,Rab GTPase activator activity; cilium; cilium axoneme assembly; cytoplasm; multicellular organismal development; positive regulation of Rab GTPase activity,PF14961;,3.00E-118,CHOYP_BROMI.2.2,,,,,,,BROMI_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275] comp12196_c0_seq1,506,38.5375,0.21634392,9,4,,2.00E-26,Q5QJ74,Tubulin-specific chaperone cofactor E-like protein (EL) (Leucine-rich repeat-containing protein 35),Tubulin-specific chaperone cofactor E-like protein (EL) (Leucine-rich repeat-containing protein 35),GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF14560;,,,,,,,,,TBCEL_HUMAN,Homo sapiens (Human), comp121977_c0_seq2,612,35.4575,0.46985307,0,0,,5.00E-21,Q95KF7,Clavesin-2 (Retinaldehyde-binding protein 1-like 2),Clavesin-2 (Retinaldehyde-binding protein 1-like 2),GO:0005794; GO:0030136; GO:0031901; GO:0005768; GO:0007040; GO:0080025; GO:0005802; GO:0005215,"Golgi apparatus; clathrin-coated vesicle; early endosome membrane; endosome; lysosome organization; phosphatidylinositol-3,5-bisphosphate binding; trans-Golgi network; transporter activity",PF00650;PF03765;,6.00E-29,CHOYP_BRAFLDRAFT_125389.1.1,,,,,,,CLVS2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),lysosome organization [GO:0007040] comp121983_c1_seq3,577,41.9411,0.40180865,6,19,,1.00E-09,Q54KZ4,Charged multivesicular body protein 6 (Vacuolar protein-sorting-associated protein 20),Charged multivesicular body protein 6 (Vacuolar protein-sorting-associated protein 20),GO:0000815; GO:0015031,ESCRT III complex; protein transport,PF03357;,,,,,,,,,CHMP6_DICDI,Dictyostelium discoideum (Slime mold),protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp121983_c2_seq1,616,35.8766,0.64048612,14,59,,1.00E-29,Q6PBQ2,Charged multivesicular body protein 7 (Chromatin-modifying protein 7),Charged multivesicular body protein 7 (Chromatin-modifying protein 7),GO:0000815; GO:0045324; GO:0008565,ESCRT III complex; late endosome to vacuole transport; protein transporter activity,PF03357;,,,,,,,,,CHMP7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),exit from mitosis [GO:0010458]; late endosome to vacuole transport [GO:0045324]; nuclear envelope reassembly [GO:0031468] comp122005_c1_seq1,624,46.3141,1.06707591,16,81,,7.00E-07,Q90738,Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) (Neural actin filament protein) (pp110),Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) (Neural actin filament protein) (pp110),GO:0005737; GO:0005856; GO:0005543,cytoplasm; cytoskeleton; phospholipid binding,PF00169;,,,,,,,,,AFAP1_CHICK,Gallus gallus (Chicken),regulation of cytoskeleton organization [GO:0051493]; regulation of signal transduction [GO:0009966] comp122013_c0_seq1,2112,34.8958,0.2998283,1479,4,male>female,,,,,,,,,,5.00E-60,ruditapes_c16274,,,,,,, comp122014_c0_seq1,375,46.9333,0.30004203,3,75,,7.00E-26,Q8WYQ5,Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8),Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8),GO:0005737; GO:0003725; GO:0046872; GO:0015630; GO:0005654; GO:0031053,cytoplasm; double-stranded RNA binding; metal ion binding; microtubule cytoskeleton; nucleoplasm; primary miRNA processing,PF00035;,3.00E-30,CHOYP_AGAP_AGAP002554.1.1,,,,,,,DGCR8_HUMAN,Homo sapiens (Human),"gene silencing by RNA [GO:0031047]; primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" comp122023_c0_seq1,494,45.9514,0.35424763,14,60,,8.00E-16,O45870,Putative neutral sphingomyelinase (EC 3.1.4.12),Putative neutral sphingomyelinase (EC 3.1.4.12),GO:0016021; GO:0046872; GO:0006665; GO:0004767,integral to membrane; metal ion binding; sphingolipid metabolic process; sphingomyelin phosphodiesterase activity,PF03372;,,,,,,,,,NSMA_CAEEL,Caenorhabditis elegans,sphingolipid metabolic process [GO:0006665] comp122030_c1_seq1,535,42.4299,0.54866333,22,11,,2.00E-38,Q6ZMV9,Kinesin-like protein KIF6,Kinesin-like protein KIF6,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,5.00E-48,CHOYP_KIF6.1.1,,,,,,,KIF6_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp122035_c0_seq1,1359,44.2237,0.53111644,4030,7835,,1.00E-43,P20397,Nucleolin (Protein C23),Nucleolin (Protein C23),GO:0003677; GO:0003723; GO:0005730; GO:0000166,DNA binding; RNA binding; nucleolus; nucleotide binding,PF00076;,,,,,,,,,NUCL_XENLA,Xenopus laevis (African clawed frog), comp122053_c0_seq1,646,39.3189,1.21252165,27,119,,4.00E-18,P0C0L4,Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain],Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain],GO:0006956; GO:0006958; GO:0004866; GO:0005576; GO:0005615; GO:0006954; GO:0045087; GO:0010951; GO:0005886; GO:0030449,"complement activation; complement activation, classical pathway; endopeptidase inhibitor activity; extracellular region; extracellular space; inflammatory response; innate immune response; negative regulation of endopeptidase activity; plasma membrane; regulation of complement activation",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO4A_HUMAN,Homo sapiens (Human),"complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427]; regulation of complement activation [GO:0030449]" comp122057_c0_seq2,417,39.3285,0.25321969,9,34,,5.00E-22,B1AUE5,Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10),Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10),GO:0005779; GO:0016558; GO:0008270,integral to peroxisomal membrane; protein import into peroxisome matrix; zinc ion binding,PF04757;,,,,,,,,,PEX10_MOUSE,Mus musculus (Mouse),peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] comp122065_c0_seq1,492,44.9187,0.72678433,13,36,,4.00E-18,Q9CQE1,Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A),Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A),GO:0005829; GO:0005739,cytosol; mitochondrion,PF07978;,,,,,,,,,NPS3B_MOUSE,Mus musculus (Mouse), comp122080_c0_seq1,4321,37.8385,0.49998481,7407,38873,,0,Q95M18,Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1),Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1),GO:0005524; GO:0030433; GO:0003723; GO:0031247; GO:0071318; GO:0005829; GO:0005783; GO:0005788; GO:0005789; GO:0050750; GO:0042470; GO:0030496; GO:0043066; GO:0048471; GO:0005886; GO:0006457; GO:0043666; GO:0001666; GO:0046790,ATP binding; ER-associated protein catabolic process; RNA binding; actin rod assembly; cellular response to ATP; cytosol; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; low-density lipoprotein particle receptor binding; melanosome; midbody; negative regulation of apoptotic process; perinuclear region of cytoplasm; plasma membrane; protein folding; regulation of phosphoprotein phosphatase activity; response to hypoxia; virion binding,PF02518;PF00183;,0,CHOYP_ENPL.3.4,3.00E-72,ruditapes2_c2642,,,,,ENPL_BOVIN,Bos taurus (Bovine),"actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457]; regulation of phosphoprotein phosphatase activity [GO:0043666]; response to hypoxia [GO:0001666]; retrograde protein transport, ER to cytosol [GO:0030970]" comp122083_c0_seq1,812,34.9754,0.60554241,3218,968,,3.00E-52,P62870,Transcription elongation factor B polypeptide 2 (Elongin 18 kDa subunit) (Elongin-B) (EloB) (RNA polymerase II transcription factor SIII subunit B) (SIII p18),Transcription elongation factor B polypeptide 2 (Elongin 18 kDa subunit) (Elongin-B) (EloB) (RNA polymerase II transcription factor SIII subunit B) (SIII p18),GO:0001076; GO:0030891; GO:0005634; GO:0045944; GO:0016567; GO:0005667,RNA polymerase II transcription factor binding transcription factor activity; VCB complex; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein ubiquitination; transcription factor complex,PF00240;,1.00E-76,CHOYP_ELOB.1.1,,,1.00E-76,AM854428.p.cg.6,6,,ELOB_RAT,Rattus norvegicus (Rat),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ubiquitination [GO:0016567]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp122089_c0_seq1,603,37.4793,0.63692583,13,97,,2.00E-19,P05434,Caltractin (20 kDa calcium-binding protein) (Centrin),Caltractin (20 kDa calcium-binding protein) (Centrin),GO:0005509; GO:0051301; GO:0007067,calcium ion binding; cell division; mitosis,PF13499;,,,,,,,,,CATR_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp122089_c1_seq1,432,43.9815,0.4863009,1,56,,,,,,,,,1.00E-23,CHOYP_BRAFLDRAFT_118451.1.1,,,,,,,,, comp122096_c0_seq1,1094,44.2413,0.73982703,63,85,,9.00E-62,Q12802,A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47),A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47),GO:0005089; GO:0097190; GO:0004691; GO:0005829; GO:0016020; GO:0046872; GO:0048011; GO:0005634; GO:0005543; GO:0043065; GO:0035023; GO:1900169; GO:0051056; GO:0004871; GO:0007264,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; cAMP-dependent protein kinase activity; cytosol; membrane; metal ion binding; neurotrophin TRK receptor signaling pathway; nucleus; phospholipid binding; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of glucocorticoid mediated signaling pathway; regulation of small GTPase mediated signal transduction; signal transducer activity; small GTPase mediated signal transduction,PF00169;PF00621;PF10522;,3.00E-36,CHOYP_AKP13.3.5,,,,,,,AKP13_HUMAN,Homo sapiens (Human),adrenergic receptor signaling pathway [GO:0071875]; adrenergic receptor signaling pathway involved in heart process [GO:0086023]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cardiac muscle hypertrophy [GO:0010611]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of protein kinase activity [GO:0045859]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] comp122103_c0_seq1,963,34.3718,0.72242284,21,35,,2.00E-42,Q9DBD2,E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII),E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII),GO:0002495; GO:0030659; GO:0031901; GO:0005768; GO:0016021; GO:0005765; GO:0005764; GO:0045347; GO:0000209; GO:0004842; GO:0008270,antigen processing and presentation of peptide antigen via MHC class II; cytoplasmic vesicle membrane; early endosome membrane; endosome; integral to membrane; lysosomal membrane; lysosome; negative regulation of MHC class II biosynthetic process; protein polyubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,7.00E-31,CHOYP_MARCH8.1.1,,,,,,,MARH8_MOUSE,Mus musculus (Mouse),adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] comp122103_c1_seq1,347,44.9568,0.86153546,9,1,,5.00E-14,O60103,ERAD-associated E3 ubiquitin-protein ligase doa10 (EC 6.3.2.-),ERAD-associated E3 ubiquitin-protein ligase doa10 (EC 6.3.2.-),GO:0030433; GO:0030176; GO:0004842; GO:0008270,ER-associated protein catabolic process; integral to endoplasmic reticulum membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,DOA10_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567] comp122104_c0_seq1,1204,43.4385,0.4405531,45,98,,1.00E-33,P0C7A1,Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96),Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96),GO:0005829; GO:0033925,cytosol; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity,PF00386;PF03644;,,,,,,,,,ENASE_CHICK,Gallus gallus (Chicken),metabolic process [GO:0008152] comp122106_c0_seq1,1007,41.4101,0.47840579,4866,1,male>female,2.00E-65,Q8AVY1,Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3),Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3),GO:0005737,cytoplasm,PF07004;,,,,,,,,,ODF3A_XENLA,Xenopus laevis (African clawed frog), comp122115_c0_seq1,1025,40.6829,0.45125043,3,0,,2.00E-85,Q5ZHN4,Protein XRP2,Protein XRP2,GO:0005524; GO:0006241; GO:0005525; GO:0006183; GO:0005096; GO:0006228; GO:0000902; GO:0005737; GO:0007010; GO:0004550; GO:0005886,ATP binding; CTP biosynthetic process; GTP binding; GTP biosynthetic process; GTPase activator activity; UTP biosynthetic process; cell morphogenesis; cytoplasm; cytoskeleton organization; nucleoside diphosphate kinase activity; plasma membrane,PF07986;,,,,,,,,,XRP2_CHICK,Gallus gallus (Chicken),cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; post-Golgi vesicle-mediated transport [GO:0006892] comp122115_c0_seq2,1226,42.9853,0.50198748,5,11,,2.00E-130,O75695,Protein XRP2,Protein XRP2,GO:0005524; GO:0006241; GO:0005525; GO:0006183; GO:0005096; GO:0006228; GO:0000902; GO:0005929; GO:0005737; GO:0007010; GO:0004550; GO:0005886; GO:0006457; GO:0015031; GO:0051082; GO:0007601,ATP binding; CTP biosynthetic process; GTP binding; GTP biosynthetic process; GTPase activator activity; UTP biosynthetic process; cell morphogenesis; cilium; cytoplasm; cytoskeleton organization; nucleoside diphosphate kinase activity; plasma membrane; protein folding; protein transport; unfolded protein binding; visual perception,PF07986;,7.00E-45,CHOYP_LOC100374553.1.1,,,,,,,XRP2_HUMAN,Homo sapiens (Human),cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; post-Golgi vesicle-mediated transport [GO:0006892]; protein folding [GO:0006457]; protein transport [GO:0015031]; visual perception [GO:0007601] comp122120_c0_seq1,622,40.5145,0.45085643,22,119,,4.00E-70,A2RRV9,Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein),Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein),GO:0051539; GO:0097361; GO:0016226; GO:0046872,"4 iron, 4 sulfur cluster binding; CIA complex; iron-sulfur cluster assembly; metal ion binding",PF02906;PF02256;,2.00E-22,CHOYP_BRAFLDRAFT_118961.1.1,,,,,,,NARFL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),iron-sulfur cluster assembly [GO:0016226] comp122127_c0_seq1,1061,33.6475,0.31026451,1619,6714,,4.00E-12,Q60668,Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1),Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1),GO:0003723; GO:0005737; GO:0000166; GO:0005634; GO:0043488; GO:0006355; GO:0030529; GO:0042162; GO:0006351,"RNA binding; cytoplasm; nucleotide binding; nucleus; regulation of mRNA stability; regulation of transcription, DNA-dependent; ribonucleoprotein complex; telomeric DNA binding; transcription, DNA-dependent",PF08143;PF00076;,,,,,,,,,HNRPD_MOUSE,Mus musculus (Mouse),"3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA stabilization [GO:0048255]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to fluoxetine [GO:0014076]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; transcription, DNA-templated [GO:0006351]" comp122132_c0_seq1,657,42.4658,0.273058,11,9,,1.00E-29,Q4X0Z5,Vacuolar protein-sorting protein bro1 (BRO domain-containing protein 1),Vacuolar protein-sorting protein bro1 (BRO domain-containing protein 1),GO:0005768; GO:0015031,endosome; protein transport,PF13949;PF03097;,1.00E-94,CHOYP_PTPN23.1.1,,,,,,,BRO1_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),protein transport [GO:0015031] comp122132_c1_seq1,853,44.5487,0.4022615,42,23,,2.00E-79,O88902,Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) (Fragment),Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) (Fragment),GO:0005929; GO:0060271; GO:0016023; GO:0005769; GO:0005932; GO:0005634; GO:0035335; GO:0015031; GO:0004725; GO:0043162,cilium; cilium morphogenesis; cytoplasmic membrane-bounded vesicle; early endosome; microtubule basal body; nucleus; peptidyl-tyrosine dephosphorylation; protein transport; protein tyrosine phosphatase activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF13949;PF03097;PF00102;,,,,,,,,,PTN23_RAT,Rattus norvegicus (Rat),cilium morphogenesis [GO:0060271]; protein transport [GO:0015031]; regulation of cell migration [GO:0030334]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp122132_c2_seq1,960,48.125,0.55896265,45,76,,,,,,,,,2.00E-13,CHOYP_PTPN23.1.1,,,,,,,,, comp122133_c0_seq1,1321,43.8304,0.4327702,52,70,,2.00E-161,P49355,Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta),Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta),GO:0004311; GO:0046872; GO:0008285; GO:0048146; GO:0018343; GO:0004660; GO:0005965; GO:0042060,farnesyltranstransferase activity; metal ion binding; negative regulation of cell proliferation; positive regulation of fibroblast proliferation; protein farnesylation; protein farnesyltransferase activity; protein farnesyltransferase complex; wound healing,PF00432;,8.00E-127,CHOYP_FNTB.1.1,,,,,,,FNTB_BOVIN,Bos taurus (Bovine),negative regulation of cell proliferation [GO:0008285]; positive regulation of fibroblast proliferation [GO:0048146]; protein farnesylation [GO:0018343]; wound healing [GO:0042060] comp122137_c0_seq1,251,48.2072,0.7191895,1,12,,4.00E-10,Q28689,Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Epithelial basolateral chloride conductance regulator) (Multidrug resistance-associated protein 2),Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Epithelial basolateral chloride conductance regulator) (Multidrug resistance-associated protein 2),GO:0005524; GO:0006200; GO:0042626; GO:0016324; GO:0016021,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; apical plasma membrane; integral to membrane",PF00664;PF00005;,,,,,,,,,MRP2_RABIT,Oryctolagus cuniculus (Rabbit), comp122141_c0_seq3,398,49.2462,0.33236361,0,0,,8.00E-06,Q8IV35,WD repeat-containing protein 49,WD repeat-containing protein 49,,,PF00400;,,,,,,,,,WDR49_HUMAN,Homo sapiens (Human), comp122143_c0_seq1,1240,40.1613,0.49122607,67,213,,2.00E-108,Q02040,"A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)","A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)",GO:0042113; GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166; GO:0051018; GO:0043484; GO:0006355; GO:0007165; GO:0005681,"B cell activation; RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding; protein kinase A binding; regulation of RNA splicing; regulation of transcription, DNA-dependent; signal transduction; spliceosomal complex",,2.00E-89,CHOYP_AK17A.1.1,,,,,,,AK17A_HUMAN,Homo sapiens (Human),"B cell activation [GO:0042113]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]" comp122148_c0_seq1,839,43.2658,0.37203469,38,51,,,,,,,,,4.00E-33,CHOYP_FANCD2.1.1,,,,,,,,, comp122148_c1_seq1,725,43.1724,0.32662639,34,15,,3.00E-54,Q9BXW9,Fanconi anemia group D2 protein (Protein FACD2),Fanconi anemia group D2 protein (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0005654; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; nucleoplasm; response to gamma radiation; synapsis,PF14631;,9.00E-47,CHOYP_BRAFLDRAFT_216683.1.1,,,,,,,FACD2_HUMAN,Homo sapiens (Human),gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp122151_c0_seq2,469,35.3945,0.41084103,0,4,,,,,,,,,8.00E-14,CHOYP_RN45S.5.5,,,,,,,,, comp122162_c0_seq1,213,41.784,1.40935224,0,2,,,,,,,,,,,2.00E-20,ruditapes_c6456,,,,,,, comp122166_c0_seq1,840,45.9524,0.38557228,54,27,,6.00E-26,P53355,Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),GO:0005524; GO:0015629; GO:0097190; GO:0005516; GO:0004683; GO:0071346; GO:0005737; GO:0007243; GO:0043066; GO:0017148; GO:0043065; GO:0046777; GO:2000310; GO:0010506,ATP binding; actin cytoskeleton; apoptotic signaling pathway; calmodulin binding; calmodulin-dependent protein kinase activity; cellular response to interferon-gamma; cytoplasm; intracellular protein kinase cascade; negative regulation of apoptotic process; negative regulation of translation; positive regulation of apoptotic process; protein autophosphorylation; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of autophagy,PF12796;PF00531;PF00069;,,,,,,,,,DAPK1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310] comp122166_c2_seq1,313,38.6581,0.44225804,8,11,,7.00E-09,Q7T3Y0,Notch-regulated ankyrin repeat-containing protein A,Notch-regulated ankyrin repeat-containing protein A,GO:0007219; GO:0002043; GO:0045746; GO:0001755; GO:0001569; GO:0050931; GO:0090263; GO:0001938; GO:0022407; GO:0006355; GO:0006351,"Notch signaling pathway; blood vessel endothelial cell proliferation involved in sprouting angiogenesis; negative regulation of Notch signaling pathway; neural crest cell migration; patterning of blood vessels; pigment cell differentiation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of endothelial cell proliferation; regulation of cell-cell adhesion; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12796;,3.00E-17,CHOYP_LOC589750.2.5,,,,,,,NARPA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; neural crest cell migration [GO:0001755]; Notch signaling pathway [GO:0007219]; patterning of blood vessels [GO:0001569]; pigment cell differentiation [GO:0050931]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp122172_c0_seq1,879,38.1115,0.53782066,5,46,,8.00E-09,P54802,Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],GO:0004561; GO:0005975; GO:0021680; GO:0006027; GO:0060119; GO:0045475; GO:0043202; GO:0007040; GO:0042474; GO:0007399; GO:0046548; GO:0044281,alpha-N-acetylglucosaminidase activity; carbohydrate metabolic process; cerebellar Purkinje cell layer development; glycosaminoglycan catabolic process; inner ear receptor cell development; locomotor rhythm; lysosomal lumen; lysosome organization; middle ear morphogenesis; nervous system development; retinal rod cell development; small molecule metabolic process,PF05089;PF12972;PF12971;,,,,,,,,,ANAG_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] comp122172_c1_seq1,586,47.4403,0.30789494,2,18,,1.00E-37,P54802,Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],GO:0004561; GO:0005975; GO:0021680; GO:0006027; GO:0060119; GO:0045475; GO:0043202; GO:0007040; GO:0042474; GO:0007399; GO:0046548; GO:0044281,alpha-N-acetylglucosaminidase activity; carbohydrate metabolic process; cerebellar Purkinje cell layer development; glycosaminoglycan catabolic process; inner ear receptor cell development; locomotor rhythm; lysosomal lumen; lysosome organization; middle ear morphogenesis; nervous system development; retinal rod cell development; small molecule metabolic process,PF05089;PF12972;PF12971;,,,,,,,,,ANAG_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] comp122176_c0_seq1,1722,34.0302,0.50819979,6811,21472,,3.00E-37,P55854,Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3B) (Smt3B),Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A),GO:0019789; GO:0005737; GO:0000776; GO:0016604; GO:0005654; GO:2000060; GO:0034504; GO:0016925,SUMO ligase activity; cytoplasm; kinetochore; nuclear body; nucleoplasm; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein localization to nucleus; protein sumoylation,PF11976;,5.00E-67,CHOYP_ISCW_ISCW005364.3.3,4.00E-72,ruditapes_c242,3.00E-67,AM855687.p.cg.6,9,,SUMO3_HUMAN,Homo sapiens (Human),global genome nucleotide-excision repair [GO:0070911]; protein sumoylation [GO:0016925] comp122179_c0_seq1,234,44.0171,0.72420429,5,32,,5.00E-15,A2AV25,Fibrinogen C domain-containing protein 1,Fibrinogen C domain-containing protein 1,GO:0008061; GO:0016021; GO:0016020; GO:0046872,chitin binding; integral to membrane; membrane; metal ion binding,PF00147;,,,,,,,,,FBCD1_MOUSE,Mus musculus (Mouse), comp122179_c1_seq1,212,39.1509,1.35241104,1,10,,9.00E-08,Q9UQP3,Tenascin-N (TN-N),Tenascin-N (TN-N),GO:0007409; GO:0016049; GO:0016477; GO:0009986; GO:0007160; GO:0005578,axonogenesis; cell growth; cell migration; cell surface; cell-matrix adhesion; proteinaceous extracellular matrix,PF00147;PF00041;,,,,,,,,,TENN_HUMAN,Homo sapiens (Human),axonogenesis [GO:0007409]; cell growth [GO:0016049]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477] comp122181_c0_seq1,565,43.7168,0.89134137,7,94,,1.00E-12,Q24307,Apoptosis 2 inhibitor (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2) (dIAP2),Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2),GO:0050829; GO:0043066; GO:0043154; GO:0061057; GO:0006964; GO:0033160; GO:0070534; GO:0007423; GO:0008270,"defense response to Gram-negative bacterium; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidoglycan recognition protein signaling pathway; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; positive regulation of protein import into nucleus, translocation; protein K63-linked ubiquitination; sensory organ development; zinc ion binding",PF00653;,,,,,,,,,IAP2_DROME,Drosophila melanogaster (Fruit fly),"defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]" comp122182_c1_seq1,202,49.0099,0.58143814,1,2,,1.00E-09,Q99KY4,Cyclin-G-associated kinase (EC 2.7.11.1),Cyclin-G-associated kinase (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0007049; GO:0005925; GO:0048471; GO:0004674,ATP binding; Golgi apparatus; cell cycle; focal adhesion; perinuclear region of cytoplasm; protein serine/threonine kinase activity,PF00226;PF00069;PF10409;,,,,,,,,,GAK_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell development [GO:0048468]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; epidermal cell differentiation [GO:0009913]; establishment of skin barrier [GO:0061436]; forebrain morphogenesis [GO:0048853]; Golgi organization [GO:0007030]; intrahepatic bile duct development [GO:0035622]; negative regulation of neuron projection development [GO:0010977]; positive regulation of neural precursor cell proliferation [GO:2000179] comp122183_c1_seq1,847,41.2043,0.28278017,3,11,,2.00E-15,Q9BRI3,Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),GO:0008324; GO:0016021; GO:0005770; GO:0005765; GO:0061090; GO:0055085; GO:0006829,cation transmembrane transporter activity; integral to membrane; late endosome; lysosomal membrane; positive regulation of sequestering of zinc ion; transmembrane transport; zinc ion transport,PF01545;,,,,,,,,,ZNT2_HUMAN,Homo sapiens (Human),positive regulation of sequestering of zinc ion [GO:0061090]; response to zinc ion [GO:0010043] comp122183_c1_seq2,797,41.1543,0.27192228,0,13,,2.00E-15,Q9BRI3,Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),GO:0008324; GO:0016021; GO:0005770; GO:0005765; GO:0061090; GO:0055085; GO:0006829,cation transmembrane transporter activity; integral to membrane; late endosome; lysosomal membrane; positive regulation of sequestering of zinc ion; transmembrane transport; zinc ion transport,PF01545;,,,,,,,,,ZNT2_HUMAN,Homo sapiens (Human),positive regulation of sequestering of zinc ion [GO:0061090]; response to zinc ion [GO:0010043] comp122199_c1_seq1,776,43.4278,0.30555606,24,45,,7.00E-36,P14629,DNA repair protein complementing XP-G cells homolog (EC 3.1.-.-) (Xeroderma pigmentosum group G-complementing protein homolog),DNA repair protein complementing XP-G cells homolog (EC 3.1.-.-) (Xeroderma pigmentosum group G-complementing protein homolog),GO:0004519; GO:0046872; GO:0090305; GO:0006289; GO:0005634; GO:0003697,endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotide-excision repair; nucleus; single-stranded DNA binding,PF00867;PF00752;,,,,,,,,,ERCC5_XENLA,Xenopus laevis (African clawed frog),nucleotide-excision repair [GO:0006289] comp122199_c2_seq1,327,50.4587,0.58311656,0,0,,7.00E-12,Q8BMI4,Flap endonuclease GEN homolog 1 (EC 3.1.-.-),Flap endonuclease GEN homolog 1 (EC 3.1.-.-),GO:0003677; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF00867;PF00752;,,,,,,,,,GEN_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] comp122199_c2_seq2,725,46.6207,0.46340514,17,43,,5.00E-30,P14629,DNA repair protein complementing XP-G cells homolog (EC 3.1.-.-) (Xeroderma pigmentosum group G-complementing protein homolog),DNA repair protein complementing XP-G cells homolog (EC 3.1.-.-) (Xeroderma pigmentosum group G-complementing protein homolog),GO:0004519; GO:0046872; GO:0090305; GO:0006289; GO:0005634; GO:0003697,endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotide-excision repair; nucleus; single-stranded DNA binding,PF00867;PF00752;,8.00E-29,CHOYP_LOC101173290.1.1,,,,,,,ERCC5_XENLA,Xenopus laevis (African clawed frog),nucleotide-excision repair [GO:0006289] comp122211_c0_seq1,939,42.066,0.50607656,41,4897,female>male,4.00E-14,O08573,Galectin-9 (Gal-9),Galectin-9 (Gal-9),GO:0030246; GO:0005737; GO:0005576; GO:0016936; GO:0007157,carbohydrate binding; cytoplasm; extracellular region; galactoside binding; heterophilic cell-cell adhesion,PF00337;,,,1.00E-69,ruditapes_c5052,,,,,LEG9_MOUSE,Mus musculus (Mouse),"cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune system process [GO:0002376]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]" comp122220_c0_seq1,381,46.9816,0.43640819,7,26,,6.00E-37,O14981,TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),GO:0005524; GO:0003677; GO:0004386; GO:0045892; GO:0005634; GO:0003700,"ATP binding; DNA binding; helicase activity; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity",PF12054;PF00271;PF00176;,,,,,,,,,BTAF1_HUMAN,Homo sapiens (Human),"negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]" comp122230_c0_seq2,1553,37.6046,0.57323409,15,18,,5.00E-53,Q90670,Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB),Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB),GO:0005524; GO:0016021; GO:0046872; GO:0004702; GO:0023014; GO:0005024,ATP binding; integral to membrane; metal ion binding; receptor signaling protein serine/threonine kinase activity; signal transduction by phosphorylation; transforming growth factor beta-activated receptor activity,PF01064;PF00069;,1.00E-37,CHOYP_AVR2B.1.1,,,,,,,AVR2B_CHICK,Gallus gallus (Chicken),activin receptor signaling pathway [GO:0032924]; cell proliferation [GO:0008283]; cranial ganglion development [GO:0061550]; mesodermal cell differentiation [GO:0048333]; negative regulation of transforming growth factor beta activation [GO:1901389]; positive regulation of neuron apoptotic process [GO:0043525] comp122230_c2_seq1,702,43.7322,0.35833902,31,90,,2.00E-56,P27041,Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB),Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB),GO:0005524; GO:0016021; GO:0004702; GO:0023014; GO:0005024,ATP binding; integral to membrane; receptor signaling protein serine/threonine kinase activity; signal transduction by phosphorylation; transforming growth factor beta-activated receptor activity,PF01064;PF00069;,,,,,,,,,AVR2B_XENLA,Xenopus laevis (African clawed frog), comp122231_c1_seq1,473,43.5518,0.50362439,19,34,,6.00E-98,Q9D4P0,ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8),ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8),GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00025;,6.00E-91,CHOYP_BRAFLDRAFT_284242.1.1,,,,,,,ARL5B_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp122232_c0_seq1,458,46.0699,0.53961191,22,21,,2.00E-37,Q3U2A8,"Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)","Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)",GO:0005524; GO:0002161; GO:0005739; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; mitochondrion; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00133;,,,,,,,,,SYVM_MOUSE,Mus musculus (Mouse),valyl-tRNA aminoacylation [GO:0006438] comp122235_c0_seq1,1057,45.5061,0.60614638,0,0,,1.00E-25,Q8BX90,Fibronectin type-III domain-containing protein 3A,Fibronectin type-III domain-containing protein 3A,GO:0000139; GO:0060009; GO:0001669; GO:0016337; GO:0005829; GO:0009566; GO:0016021; GO:0007286; GO:0012506,Golgi membrane; Sertoli cell development; acrosomal vesicle; cell-cell adhesion; cytosol; fertilization; integral to membrane; spermatid development; vesicle membrane,PF00041;,,,,,,,,,FND3A_MOUSE,Mus musculus (Mouse),fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; single organismal cell-cell adhesion [GO:0016337]; spermatid development [GO:0007286] comp122235_c0_seq2,1406,46.0882,0.65797895,21,0,,4.00E-61,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp122235_c1_seq1,1000,45.7,0.51764014,12,4,,4.00E-21,Q00872,"Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)","Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)",GO:0007155; GO:0005829; GO:0030049; GO:0030016; GO:0032982; GO:0008307; GO:0031432,cell adhesion; cytosol; muscle filament sliding; myofibril; myosin filament; structural constituent of muscle; titin binding,PF00041;PF07679;,,,,,,,,,MYPC1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp122258_c0_seq1,607,45.799,0.5349911,17,63,,2.00E-67,P17735,Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase),Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase),GO:0006103; GO:0006559; GO:0080130; GO:0004838; GO:0016597; GO:0009058; GO:0034641; GO:0005829; GO:0006536; GO:0005739; GO:0030170; GO:0051384; GO:0046689; GO:0006979; GO:0006572,2-oxoglutarate metabolic process; L-phenylalanine catabolic process; L-phenylalanine:2-oxoglutarate aminotransferase activity; L-tyrosine:2-oxoglutarate aminotransferase activity; amino acid binding; biosynthetic process; cellular nitrogen compound metabolic process; cytosol; glutamate metabolic process; mitochondrion; pyridoxal phosphate binding; response to glucocorticoid stimulus; response to mercury ion; response to oxidative stress; tyrosine catabolic process,PF00155;PF07706;,4.00E-25,CHOYP_BRAFLDRAFT_275580.2.2,,,,,,,ATTY_HUMAN,Homo sapiens (Human),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572] comp122267_c1_seq2,1189,44.7435,0.51149832,0,0,,3.00E-65,Q4KLI9,F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),GO:0080008; GO:0019005; GO:0031146; GO:0051298; GO:0005737; GO:0016567,Cul4-RING ubiquitin ligase complex; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication; cytoplasm; protein ubiquitination,PF12937;PF00400;,,,,,,,,,FBXW5_RAT,Rattus norvegicus (Rat),centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp122267_c1_seq4,650,46,0.52688974,0,0,,4.00E-67,Q9QXW2,F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),GO:0080008; GO:0019005; GO:0031146; GO:0051298; GO:0005737; GO:0007067; GO:0016567,Cul4-RING ubiquitin ligase complex; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication; cytoplasm; mitosis; protein ubiquitination,PF12937;PF00400;,7.00E-67,CHOYP_LOC100142053.2.2,,,,,,,FBXW5_MOUSE,Mus musculus (Mouse),centrosome duplication [GO:0051298]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp122280_c0_seq1,1563,35.8925,0.40689977,2390,11226,,2.00E-135,P24495,Proteasome subunit alpha type-2 (EC 3.4.25.1) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (xC3) (Proteasome component C3),Proteasome subunit alpha type-2 (EC 3.4.25.1) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (xC3) (Proteasome component C3),GO:0005737; GO:0005634; GO:0005839; GO:0019773; GO:0004298; GO:0006511,"cytoplasm; nucleus; proteasome core complex; proteasome core complex, alpha-subunit complex; threonine-type endopeptidase activity; ubiquitin-dependent protein catabolic process",PF00227;PF10584;,2.00E-174,CHOYP_PSA2.1.1,9.00E-144,ruditapes2_c2788,2.00E-71,AM864414.p.cg.6,8,,PSA2_XENLA,Xenopus laevis (African clawed frog),ubiquitin-dependent protein catabolic process [GO:0006511] comp122282_c0_seq1,2240,46.25,0.60133508,129,66,,0,P56941,Niemann-Pick C1 protein,Niemann-Pick C1 protein,GO:0008206; GO:0015485; GO:0042632; GO:0008203; GO:0030301; GO:0005783; GO:0005576; GO:0008158; GO:0005887; GO:0031902; GO:0005765; GO:0007041; GO:0005764; GO:0005635; GO:0048471; GO:0006486,bile acid metabolic process; cholesterol binding; cholesterol homeostasis; cholesterol metabolic process; cholesterol transport; endoplasmic reticulum; extracellular region; hedgehog receptor activity; integral to plasma membrane; late endosome membrane; lysosomal membrane; lysosomal transport; lysosome; nuclear envelope; perinuclear region of cytoplasm; protein glycosylation,PF16414;PF02460;PF12349;,7.00E-86,CHOYP_BRAFLDRAFT_116988.3.3,,,,,,,NPC1_PIG,Sus scrofa (Pig),bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; lysosomal transport [GO:0007041]; protein glycosylation [GO:0006486] comp122283_c0_seq1,594,41.7508,0.73600469,34,33,,3.00E-23,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp122283_c0_seq2,342,44.7368,0.70576735,0,0,,3.00E-10,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp122285_c0_seq2,842,47.6247,1.06953233,0,0,,3.00E-47,Q8CGN4,BCL-6 corepressor (BCoR),BCL-6 corepressor (BCoR),GO:0031519; GO:0007507; GO:0035518; GO:0030502; GO:0000415; GO:0051572; GO:0070171; GO:0000122; GO:0005634; GO:0042476; GO:0060021; GO:0065001; GO:0003714; GO:0044212; GO:0006351; GO:0004842,"PcG protein complex; heart development; histone H2A monoubiquitination; negative regulation of bone mineralization; negative regulation of histone H3-K36 methylation; negative regulation of histone H3-K4 methylation; negative regulation of tooth mineralization; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis; palate development; specification of axis polarity; transcription corepressor activity; transcription regulatory region DNA binding; transcription, DNA-dependent; ubiquitin-protein ligase activity",PF12796;PF15808;PF16553;,7.00E-11,CHOYP_BCOR.1.1,,,,,,,BCOR_MOUSE,Mus musculus (Mouse),"heart development [GO:0007507]; histone H2A monoubiquitination [GO:0035518]; negative regulation of bone mineralization [GO:0030502]; negative regulation of histone H3-K36 methylation [GO:0000415]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; palate development [GO:0060021]; specification of axis polarity [GO:0065001]; transcription, DNA-templated [GO:0006351]" comp122285_c0_seq3,1363,41.3793,1.06504849,20,15,,3.00E-45,Q8CGN4,BCL-6 corepressor (BCoR),BCL-6 corepressor (BCoR),GO:0031519; GO:0007507; GO:0035518; GO:0030502; GO:0000415; GO:0051572; GO:0070171; GO:0000122; GO:0005634; GO:0042476; GO:0060021; GO:0065001; GO:0003714; GO:0044212; GO:0006351; GO:0004842,"PcG protein complex; heart development; histone H2A monoubiquitination; negative regulation of bone mineralization; negative regulation of histone H3-K36 methylation; negative regulation of histone H3-K4 methylation; negative regulation of tooth mineralization; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis; palate development; specification of axis polarity; transcription corepressor activity; transcription regulatory region DNA binding; transcription, DNA-dependent; ubiquitin-protein ligase activity",PF12796;PF15808;PF16553;,,,,,,,,,BCOR_MOUSE,Mus musculus (Mouse),"heart development [GO:0007507]; histone H2A monoubiquitination [GO:0035518]; negative regulation of bone mineralization [GO:0030502]; negative regulation of histone H3-K36 methylation [GO:0000415]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; palate development [GO:0060021]; specification of axis polarity [GO:0065001]; transcription, DNA-templated [GO:0006351]" comp122295_c0_seq1,1240,40.4839,0.49446203,5604,26261,,1.00E-136,B5RI54,Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit),Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity; translational initiation,PF01398;,1.00E-124,CHOYP_LOC100368639.1.1,0,ruditapes_c32371,,,,,EIF3H_SALSA,Salmo salar (Atlantic salmon),formation of translation preinitiation complex [GO:0001731]; translational initiation [GO:0006413] comp122304_c0_seq2,1110,38.7387,0.83340388,5,210,,1.00E-32,O75897,Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),GO:0050427; GO:0005829; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,3.00E-15,ruditapes_c21958,,,,,ST1C4_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923] comp122304_c0_seq3,213,39.9061,0.50472811,0,36,,9.00E-06,Q7T2V2,Cytosolic sulfotransferase 3 (EC 2.8.2.-) (SULT1 ST3),Cytosolic sulfotransferase 3 (EC 2.8.2.-) (SULT1 ST3),GO:0006584; GO:0005737; GO:0008202; GO:0008146; GO:0006805,catecholamine metabolic process; cytoplasm; steroid metabolic process; sulfotransferase activity; xenobiotic metabolic process,PF00685;,3.00E-15,CHOYP_LOC100015166.1.1,4.00E-17,ruditapes_c7659,,,,,ST1S3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805] comp122304_c1_seq1,376,39.6277,1.22315213,1,36,,4.00E-11,Q95JD5,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-),GO:0004062; GO:0005737; GO:0009812; GO:0008202; GO:0051923; GO:0042403; GO:0006805,aryl sulfotransferase activity; cytoplasm; flavonoid metabolic process; steroid metabolic process; sulfation; thyroid hormone metabolic process; xenobiotic metabolic process,PF00685;,,,3.00E-21,ruditapes_c22890,,,,,ST1B1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp122304_c2_seq1,227,37.8855,0.52145094,0,19,,5.00E-09,O75897,Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),GO:0050427; GO:0005829; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,1.00E-17,ruditapes2_c987,,,,,ST1C4_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923] comp122325_c0_seq1,870,41.8391,1.01253747,305,3978,,2.00E-86,Q8R0F8,"Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1)","Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.3)",GO:0018773; GO:0047621; GO:0005829; GO:0034545; GO:0046872; GO:0005743,acetylpyruvate hydrolase activity; acylpyruvate hydrolase activity; cytosol; fumarylpyruvate hydrolase activity; metal ion binding; mitochondrial inner membrane,PF01557;,3.00E-79,CHOYP_PIGS.1.1,,,,,,,FAHD1_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp122358_c0_seq1,987,39.0071,1.17663738,11,91,,4.00E-52,Q8N9I5,Fatty acid desaturase 6 (EC 1.14.19.-),Fatty acid desaturase 6 (EC 1.14.19.-),GO:0006633; GO:0016021; GO:0016491,fatty acid biosynthetic process; integral to membrane; oxidoreductase activity,PF00487;,6.00E-32,CHOYP_LOC100374197.1.1,,,,,,,FADS6_HUMAN,Homo sapiens (Human),fatty acid biosynthetic process [GO:0006633] comp122358_c1_seq1,685,37.2263,0.38111192,1228,5356,,3.00E-49,Q5RAY0,Prefoldin subunit 5,Prefoldin subunit 5,GO:0005634; GO:0016272; GO:0006457,nucleus; prefoldin complex; protein folding,PF02996;,4.00E-45,CHOYP_LOC101064793.1.1,2.00E-78,ruditapes2_c1615,,,,,PFD5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein folding [GO:0006457] comp122371_c0_seq1,1856,46.8211,0.48417705,107,0,,1.00E-42,O81635,Kinesin-4 (Kinesin-like protein D),Kinesin-4 (Kinesin-like protein D),GO:0005524; GO:0016887; GO:0005737; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018,ATP binding; ATPase activity; cytoplasm; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement,PF00307;PF00225;,2.00E-129,CHOYP_BRAFLDRAFT_118210.1.1,,,,,,,ATK4_ARATH,Arabidopsis thaliana (Mouse-ear cress),microtubule-based movement [GO:0007018] comp122373_c0_seq1,611,44.6809,0.92327834,20,3,,7.00E-30,B0JZG0,Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2),Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00860;,3.00E-32,CHOYP_NEMVEDRAFT_V1G82490.1.1,,,,,,,S23A2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp122374_c0_seq1,255,49.4118,0.45150606,8,12,,2.00E-17,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp122379_c0_seq1,360,47.2222,0.84988885,885,838,,,,,,,,,6.00E-14,CHOYP_RHO-5.1.1,,,,,,,,, comp122383_c0_seq1,310,30,0.14384979,13,19,,,,,,,,,3.00E-11,CHOYP_LOC100495383.1.1,,,,,,,,, comp122384_c0_seq1,722,43.0748,0.44955318,24,28,,8.00E-48,O35394,Prenylated Rab acceptor protein 1 (PRA1 family protein 1),Prenylated Rab acceptor protein 1 (PRA1 family protein 1),GO:0005794; GO:0030054; GO:0016021; GO:0005886; GO:0030674; GO:0008021; GO:0016192,"Golgi apparatus; cell junction; integral to membrane; plasma membrane; protein binding, bridging; synaptic vesicle; vesicle-mediated transport",PF03208;,5.00E-44,CHOYP_BRAFLDRAFT_125634.1.1,,,,,,,PRAF1_RAT,Rattus norvegicus (Rat),vesicle-mediated transport [GO:0016192] comp122384_c0_seq2,361,44.0443,0.45837642,0,0,,1.00E-07,P93829,PRA1 family protein D (AtPRA1.D) (CAMV MOVEMENT PROTEIN-INTERACTING PROTEIN 7) (Prenylated Rab acceptor 5),PRA1 family protein D (AtPRA1.D) (CAMV MOVEMENT PROTEIN-INTERACTING PROTEIN 7) (Prenylated Rab acceptor 5),GO:0005783; GO:0010008; GO:0016021; GO:0019048; GO:0046739; GO:0016192,endoplasmic reticulum; endosome membrane; integral to membrane; modulation by virus of host morphology or physiology; spread of virus in multicellular host; vesicle-mediated transport,PF03208;,,,,,,,,,PRA1D_ARATH,Arabidopsis thaliana (Mouse-ear cress),transport of virus in multicellular host [GO:0046739]; vesicle-mediated transport [GO:0016192] comp122385_c0_seq1,237,43.4599,0.53847113,5,18,,6.00E-13,Q9V0L2,Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A),Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A),GO:0004069; GO:0080130; GO:0009058; GO:0005737; GO:0030170,L-aspartate:2-oxoglutarate aminotransferase activity; L-phenylalanine:2-oxoglutarate aminotransferase activity; biosynthetic process; cytoplasm; pyridoxal phosphate binding,PF00155;,,,,,,,,,AAT_PYRAB,Pyrococcus abyssi (strain GE5 / Orsay),biosynthetic process [GO:0009058] comp122385_c1_seq1,1271,37.6869,0.59905846,14,30,,4.00E-75,Q8QZR1,Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase),Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase),GO:0006103; GO:0006559; GO:0080130; GO:0004838; GO:0016597; GO:0009058; GO:0006536; GO:0005739; GO:0030170; GO:0051384; GO:0046689; GO:0006979; GO:0006572,2-oxoglutarate metabolic process; L-phenylalanine catabolic process; L-phenylalanine:2-oxoglutarate aminotransferase activity; L-tyrosine:2-oxoglutarate aminotransferase activity; amino acid binding; biosynthetic process; glutamate metabolic process; mitochondrion; pyridoxal phosphate binding; response to glucocorticoid stimulus; response to mercury ion; response to oxidative stress; tyrosine catabolic process,PF00155;PF07706;,2.00E-26,CHOYP_BRAFLDRAFT_275580.2.2,,,,,,,ATTY_MOUSE,Mus musculus (Mouse),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572] comp122386_c0_seq1,676,44.6746,1.31109442,4248,4,male>female,2.00E-11,Q9DA42,Uncharacterized protein C20orf85 homolog,Uncharacterized protein C20orf85 homolog,,,PF14945;,,,,,,,,,CT085_MOUSE,Mus musculus (Mouse), comp122397_c0_seq1,226,41.5929,0.10582958,13,0,,6.00E-15,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,3.00E-14,CHOYP_SACS.12.17,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp122397_c0_seq2,219,43.8356,0.29268903,9,0,,3.00E-16,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp122398_c0_seq1,1736,45.2765,0.89300131,79,37,,2.00E-98,Q1L8X9,Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8),Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8),GO:0030054; GO:0050957; GO:0016021; GO:0043005; GO:0006836; GO:0050803; GO:0006814; GO:0015293; GO:0030672; GO:0060005,cell junction; equilibrioception; integral to membrane; neuron projection; neurotransmitter transport; regulation of synapse structure and activity; sodium ion transport; symporter activity; synaptic vesicle membrane; vestibular reflex,PF07690;,4.00E-11,CHOYP_VGLU2.1.3,,,,,,,VGLU3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),equilibrioception [GO:0050957]; neurotransmitter transport [GO:0006836]; regulation of synapse structure or activity [GO:0050803]; sodium ion transport [GO:0006814]; vestibular reflex [GO:0060005] comp122400_c0_seq1,1242,44.2029,0.61163164,55,57,,6.00E-63,Q9UKG1,"DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)","DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)",GO:0006915; GO:0007049; GO:0008283; GO:0005829; GO:0031901; GO:0010008; GO:0008286; GO:0005634; GO:0005543; GO:0043065; GO:0090003; GO:0046324; GO:0012506,apoptotic process; cell cycle; cell proliferation; cytosol; early endosome membrane; endosome membrane; insulin receptor signaling pathway; nucleus; phospholipid binding; positive regulation of apoptotic process; regulation of establishment of protein localization to plasma membrane; regulation of glucose import; vesicle membrane,PF00169;PF00640;,2.00E-71,CHOYP_DP13A.2.3,,,,,,,DP13A_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell proliferation [GO:0008283]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; insulin receptor signaling pathway [GO:0008286]; regulation of establishment of protein localization to plasma membrane [GO:0090003]; regulation of glucose import [GO:0046324]; signal transduction [GO:0007165] comp122406_c0_seq1,1809,33.7756,0.70460937,5474,13003,,2.00E-92,Q1HR36,14-3-3 protein zeta,14-3-3 protein zeta,GO:0005737,cytoplasm,PF00244;,3.00E-25,CHOYP_1433G.1.2,1.00E-21,ruditapes_c29829,,,,,1433Z_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp122411_c0_seq1,2129,39.737,0.46442858,166,88,,1.00E-33,Q9NQV7,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0034968; GO:0018024; GO:0006311; GO:0046872; GO:0003676; GO:0005654; GO:0010845; GO:0006355; GO:0006351,"chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; meiotic gene conversion; metal ion binding; nucleic acid binding; nucleoplasm; positive regulation of reciprocal meiotic recombination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;PF13912;,,,,,,,,,PRDM9_HUMAN,Homo sapiens (Human),"meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122419_c0_seq1,796,44.4724,0.51915142,25,35,,4.00E-116,Q9NTJ4,Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1),Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1),GO:0004559; GO:0030246; GO:0006013; GO:0008270,alpha-mannosidase activity; carbohydrate binding; mannose metabolic process; zinc ion binding,PF09261;PF01074;PF07748;,5.00E-114,CHOYP_MA2C1.1.1,,,,,,,MA2C1_HUMAN,Homo sapiens (Human),mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517] comp122428_c0_seq1,1209,42.349,0.78937612,138,609,,0,P21953,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta)","2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta)",GO:0003863; GO:0003826; GO:0009083; GO:0016831; GO:0034641; GO:0005947; GO:0051591; GO:0051384; GO:0007584,3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; alpha-ketoacid dehydrogenase activity; branched-chain amino acid catabolic process; carboxy-lyase activity; cellular nitrogen compound metabolic process; mitochondrial alpha-ketoglutarate dehydrogenase complex; response to cAMP; response to glucocorticoid stimulus; response to nutrient,PF02779;PF02780;,2.00E-109,CHOYP_LOC100367645.1.1,,,,,,,ODBB_HUMAN,Homo sapiens (Human),branched-chain amino acid catabolic process [GO:0009083]; glyoxylate metabolic process [GO:0046487] comp122429_c0_seq1,305,44.5902,1.3339289,0,67,,1.00E-11,Q93324,Probable beta-mannosidase (EC 3.2.1.25) (Mannanase) (Mannase),Probable beta-mannosidase (EC 3.2.1.25) (Mannanase) (Mannase),GO:0004567; GO:0005764; GO:0046355,beta-mannosidase activity; lysosome; mannan catabolic process,PF00703;,,,,,,,,,MANBA_CAEEL,Caenorhabditis elegans,carbohydrate metabolic process [GO:0005975] comp122429_c0_seq2,233,46.7811,0.78842423,0,20,,4.00E-07,Q5BCI8,Probable beta-mannosidase A (EC 3.2.1.25) (Mannanase A) (Mannase A),Beta-mannosidase A (EC 3.2.1.25) (Mannanase A) (Mannase A),GO:0004567; GO:0005576; GO:0046355,beta-mannosidase activity; extracellular region; mannan catabolic process,PF00703;,,,,,,,,,MANBA_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272] comp122429_c1_seq2,373,48.2574,0.60503173,4,29,,4.00E-20,Q8K2I4,Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase),Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase),GO:0004567; GO:0006516; GO:0005764; GO:0046355; GO:0005537,beta-mannosidase activity; glycoprotein catabolic process; lysosome; mannan catabolic process; mannose binding,PF02836;PF02837;,,,,,,,,,MANBA_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516] comp122434_c0_seq1,765,42.7451,0.34881663,59,52,,4.00E-33,Q5ZIG0,Neurochondrin,Neurochondrin,GO:0005829; GO:0030425; GO:0031175; GO:0043025,cytosol; dendrite; neuron projection development; neuronal cell body,PF05536;,,,,,,,,,NCDN_CHICK,Gallus gallus (Chicken),neuron projection development [GO:0031175] comp122434_c1_seq1,843,41.5184,0.47297007,55,28,,4.00E-22,Q9VI25,Neurochondrin homolog (dNeurochondrin),Neurochondrin homolog (dNeurochondrin),GO:0030425; GO:0003012; GO:0043025,dendrite; muscle system process; neuronal cell body,PF05536;,,,,,,,,,NCDN_DROME,Drosophila melanogaster (Fruit fly),muscle system process [GO:0003012] comp122436_c0_seq1,901,40.7325,0.89034568,38,258,,8.00E-68,Q9HAJ7,Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like),Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like),GO:0003677; GO:0046872; GO:0005730; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13867;PF13866;,2.00E-36,CHOYP_LOC583865.2.2,,,,,,,SP30L_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122439_c0_seq1,303,44.5545,0.33362962,10,17,,3.00E-30,Q9JI39,"ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein)","ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein)",GO:0005524; GO:0016021; GO:0032592; GO:0005743; GO:0015421,ATP binding; integral to membrane; integral to mitochondrial membrane; mitochondrial inner membrane; oligopeptide-transporting ATPase activity,PF00664;PF00005;,,,,,,,,,ABCBA_MOUSE,Mus musculus (Mouse),transmembrane transport [GO:0055085] comp122441_c0_seq1,272,47.7941,0.38852518,0,36,,5.00E-15,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp122441_c1_seq1,396,46.9697,0.13848926,3,25,,1.00E-14,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp122443_c0_seq1,439,44.6469,0.59583643,4,19,,7.00E-40,Q96KN3,Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2),Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2),GO:0003677; GO:0015629; GO:0005737; GO:0015630; GO:0005634; GO:0006357; GO:0043565; GO:0003700,DNA binding; actin cytoskeleton; cytoplasm; microtubule cytoskeleton; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF05920;PF16493;,8.00E-58,CHOYP_PKNX1.1.1,,,,,,,PKNX2_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp122454_c0_seq1,1180,41.3559,0.42482045,65,19,,1.00E-100,Q5M9B1,SPRY domain-containing SOCS box protein 3 (SSB-3),SPRY domain-containing SOCS box protein 3 (SSB-3),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF07525;PF00622;,6.00E-64,CHOYP_SPSB3.1.1,,,,,,,SPSB3_XENLA,Xenopus laevis (African clawed frog),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp122462_c0_seq1,240,30,0.37923554,0,6,,,,,,,,,,,2.00E-14,ruditapes_c17805,,,,,,, comp122467_c0_seq1,1033,43.4656,0.63903569,78,29,,1.00E-46,P97393,Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),GO:0005525; GO:0005096; GO:0005737; GO:0016020; GO:0043547; GO:0030335; GO:0002053; GO:0008361; GO:0007264,GTP binding; GTPase activator activity; cytoplasm; membrane; positive regulation of GTPase activity; positive regulation of cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; small GTPase mediated signal transduction,PF01846;PF00071;PF00620;PF16512;,,,,,,,,,RHG05_MOUSE,Mus musculus (Mouse),positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264] comp122471_c0_seq1,989,44.186,0.83611419,3,10,,4.00E-11,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp122480_c1_seq1,203,37.931,0.56199711,18,66,,,,,,,,,2.00E-16,CHOYP_ITIH4.1.1,3.00E-18,ruditapes_c27756,,,,,,, comp122481_c1_seq1,385,43.3766,0.66437626,8,62,,,,,,,,,,,5.00E-19,ruditapes_c29520,,,,,,, comp122482_c0_seq1,636,39.4654,0.68764458,3,3531,female>male,2.00E-29,Q9DGJ3,Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog),Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog),GO:0008203; GO:0005783; GO:0005576,cholesterol metabolic process; endoplasmic reticulum; extracellular region,PF02221;,,,,,,,,,NPC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cholesterol metabolic process [GO:0008203] comp122484_c0_seq1,2471,42.2501,0.57662284,100,459,,5.00E-07,Q80V24,Transcription cofactor vestigial-like protein 4 (Vgl-4),Transcription cofactor vestigial-like protein 4 (Vgl-4),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15245;,,,,,,,,,VGLL4_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122487_c0_seq1,447,45.8613,0.61095182,22,9,,2.00E-17,Q9BX63,Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1),Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0000077; GO:0005737; GO:0006302; GO:0046872; GO:0031965; GO:0006357,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA damage checkpoint; cytoplasm; double-strand break repair; metal ion binding; nuclear membrane; regulation of transcription from RNA polymerase II promoter",PF06733;PF13307;,,,,,,,,,FANCJ_HUMAN,Homo sapiens (Human),cellular response to vitamin [GO:0071295]; DNA damage checkpoint [GO:0000077]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; negative regulation of cell proliferation [GO:0008285]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; strand displacement [GO:0000732] comp122500_c0_seq1,469,38.3795,0.93023679,21,46,,9.00E-16,Q0D2G3,Transmembrane protein 254,Transmembrane protein 254,GO:0016021,integral to membrane,PF14934;,,,,,,,,,CJ057_BOVIN,Bos taurus (Bovine), comp122506_c0_seq2,565,49.7345,1.26867438,20,0,,2.00E-07,Q61361,Brevican core protein,Brevican core protein,GO:0030246; GO:0007155; GO:0021766; GO:0005540; GO:0005578,carbohydrate binding; cell adhesion; hippocampus development; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,PGCB_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; hippocampus development [GO:0021766]; regulation of neuronal synaptic plasticity [GO:0048168]; skeletal system development [GO:0001501] comp122506_c0_seq3,579,48.0138,1.1746413,30,0,,1.00E-07,Q61361,Brevican core protein,Brevican core protein,GO:0030246; GO:0007155; GO:0021766; GO:0005540; GO:0005578,carbohydrate binding; cell adhesion; hippocampus development; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,PGCB_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; hippocampus development [GO:0021766]; regulation of neuronal synaptic plasticity [GO:0048168]; skeletal system development [GO:0001501] comp122507_c0_seq2,1038,44.5087,0.59050922,2,0,,,,,,,,,1.00E-66,CHOYP_LOC100116049.1.1,,,,,,,,, comp122508_c0_seq1,1131,39.7878,0.56845617,49,105,,1.00E-107,O57590,Surfeit locus protein 4,Surfeit locus protein 4,GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF02077;,1.00E-141,CHOYP_LOC100373170.1.1,,,,,,,SURF4_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes), comp122512_c1_seq2,771,39.2996,0.5139366,0,0,,8.00E-31,Q7YS61,tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2),tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2),GO:0003677; GO:0006306; GO:0003723; GO:0008168; GO:0005634; GO:0008033,DNA binding; DNA methylation; RNA binding; methyltransferase activity; nucleus; tRNA processing,PF00145;,2.00E-12,CHOYP_TRDMT1.1.1,,,,,,,TRDMT_BOVIN,Bos taurus (Bovine), comp122514_c0_seq1,375,29.6,0.73726014,7,11,,9.00E-07,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp122518_c0_seq1,362,40.884,0.79678676,4,0,,3.00E-13,Q96SZ4,Zinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206),Zinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206),GO:0046872; GO:0045892; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSC10_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]" comp122518_c0_seq2,525,43.2381,0.82367978,4,63,,5.00E-15,Q4VBD9,GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GO:0001658; GO:0005737; GO:0046872; GO:0000122; GO:0005730; GO:0005634; GO:0043565; GO:0006351,"branching involved in ureteric bud morphogenesis; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,GZF1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp122527_c0_seq1,1325,47.1698,0.95458527,48,95,,6.00E-131,Q95334,Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249),Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249),GO:0016477; GO:0008283; GO:0016021; GO:0070006; GO:0006508; GO:0003081; GO:0008270,cell migration; cell proliferation; integral to membrane; metalloaminopeptidase activity; proteolysis; regulation of systemic arterial blood pressure by renin-angiotensin; zinc ion binding,PF11838;PF01433;,9.00E-88,CHOYP_ENPEP.1.1,,,,,,,AMPE_PIG,Sus scrofa (Pig),cell migration [GO:0016477]; cell proliferation [GO:0008283]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] comp122548_c0_seq1,689,44.2671,0.51366372,45242,138131,,2.00E-90,Q09JW2,60S ribosomal protein L17,60S ribosomal protein L17,GO:0015934; GO:0003735; GO:0006412,large ribosomal subunit; structural constituent of ribosome; translation,PF00237;,1.00E-107,CHOYP_RL17.6.7,0,ruditapes_lrc15185,,,,,RL17_ARGMO,Argas monolakensis (Mono lake bird tick),translation [GO:0006412] comp122549_c0_seq1,933,41.2647,0.54293369,31,122,,7.00E-15,A1L157,Tetraspanin-11 (Tspan-11),Tetraspanin-11 (Tspan-11),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN11_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166] comp122553_c0_seq1,1302,40.169,0.51791751,31,138,,1.00E-33,P14046,Alpha-1-inhibitor 3 (Alpha-1-inhibitor 3 variant II) (Alpha-1-inhibitor III),Alpha-1-inhibitor 3 (Alpha-1-inhibitor 3 variant II) (Alpha-1-inhibitor III),GO:0005615; GO:0006954; GO:0010951; GO:0030414; GO:0004867,extracellular space; inflammatory response; negative regulation of endopeptidase activity; peptidase inhibitor activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,A1I3_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954] comp122555_c0_seq1,596,49.3289,0.47231146,9,58,,2.00E-22,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp122555_c1_seq1,304,48.0263,0.57930351,8,5,,4.00E-09,Q76LX8,A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease),A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease),GO:0005509; GO:0009986; GO:0007160; GO:0005615; GO:0009100; GO:0005178; GO:0007229; GO:0004222; GO:0008237; GO:0043171; GO:0030168; GO:0016485; GO:0005578; GO:0006508; GO:0008270,calcium ion binding; cell surface; cell-matrix adhesion; extracellular space; glycoprotein metabolic process; integrin binding; integrin-mediated signaling pathway; metalloendopeptidase activity; metallopeptidase activity; peptide catabolic process; platelet activation; protein processing; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF01421;PF00090;,,,,,,,,,ATS13_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; glycoprotein metabolic process [GO:0009100]; integrin-mediated signaling pathway [GO:0007229]; peptide catabolic process [GO:0043171]; platelet activation [GO:0030168]; protein O-linked fucosylation [GO:0036066]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to interferon-gamma [GO:0034341]; response to interleukin-4 [GO:0070670]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612] comp122555_c3_seq1,958,41.7537,0.36165973,26,45,,6.00E-86,Q13591,Semaphorin-5A (Semaphorin-F) (Sema F),Semaphorin-5A (Semaphorin-F) (Sema F),GO:0007411; GO:0008046; GO:0007155; GO:0007267; GO:0016021; GO:0001569; GO:0005886,axon guidance; axon guidance receptor activity; cell adhesion; cell-cell signaling; integral to membrane; patterning of blood vessels; plasma membrane,PF01403;PF00090;,7.00E-37,CHOYP_SEM5B.1.1,,,,,,,SEM5A_HUMAN,Homo sapiens (Human),axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] comp122561_c0_seq1,551,49.7278,0.38251725,24,12,,1.00E-22,Q9HCE0,Ectopic P granules protein 5 homolog,Ectopic P granules protein 5 homolog,GO:0006914,autophagy,,,,,,,,,,EPG5_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; endocytic recycling [GO:0032456] comp122564_c0_seq2,278,35.2518,1.10133004,4,5,,,,,,,,,5.00E-13,CHOYP_contig_020768,,,,,,,,, comp122572_c0_seq1,678,45.4277,0.43254012,67495,161755,,1.00E-52,O77302,40S ribosomal protein S10,40S ribosomal protein S10,GO:0005840,ribosome,PF03501;,3.00E-78,CHOYP_PROM1.3.3,8.00E-121,ruditapes_lrc32602,,,,,RS10_LUMRU,Lumbricus rubellus (Humus earthworm), comp122574_c0_seq2,466,36.0515,0.06713659,1,0,,,,,,,,,2.00E-15,CHOYP_PHUM_PHUM387860.1.1,,,,,,,,, comp122575_c0_seq1,495,43.2323,0.56398376,969,5584,,,,,,,,,,,3.00E-48,ruditapes_c2074,,,,,,, comp122575_c0_seq2,810,41.7284,0.94662708,47257,149100,,3.00E-107,P55935,40S ribosomal protein S9,40S ribosomal protein S9,GO:0000022; GO:0000228; GO:0005730; GO:0019843; GO:0005840; GO:0015935; GO:0003735; GO:0006412,mitotic spindle elongation; nuclear chromosome; nucleolus; rRNA binding; ribosome; small ribosomal subunit; structural constituent of ribosome; translation,PF00163;PF01479;,5.00E-127,CHOYP_BRAFLDRAFT_114843.2.2,1.00E-151,ruditapes2_c5138,,,,,RS9_DROME,Drosophila melanogaster (Fruit fly),mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; positive regulation of translational fidelity [GO:0045903]; translation [GO:0006412] comp122577_c1_seq1,710,47.6056,0.51193535,38,8,,9.00E-49,Q0KIA2,PP2C-like domain-containing protein CG9801,PP2C-like domain-containing protein CG9801,GO:0003824; GO:0008152,catalytic activity; metabolic process,,2.00E-56,CHOYP_TSP_01615.1.1,,,,,,,Y9801_DROME,Drosophila melanogaster (Fruit fly), comp122577_c1_seq2,342,47.3684,0.52932551,0,0,,1.00E-23,Q0KIA2,PP2C-like domain-containing protein CG9801,PP2C-like domain-containing protein CG9801,GO:0003824; GO:0008152,catalytic activity; metabolic process,,,,,,,,,,Y9801_DROME,Drosophila melanogaster (Fruit fly), comp122580_c0_seq1,1198,46.5776,0.82102124,75,0,,5.00E-48,Q9UQ26,Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3),Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3),GO:0019933; GO:0017156; GO:0048791; GO:0030054; GO:0030073; GO:0006886; GO:0046872; GO:0042734; GO:0017157; GO:0042391,cAMP-mediated signaling; calcium ion-dependent exocytosis; calcium ion-dependent exocytosis of neurotransmitter; cell junction; insulin secretion; intracellular protein transport; metal ion binding; presynaptic membrane; regulation of exocytosis; regulation of membrane potential,PF00168;PF02318;,2.00E-26,CHOYP_RIMS2.2.3,,,,,,,RIMS2_HUMAN,Homo sapiens (Human),calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669] comp122582_c0_seq1,969,35.6037,0.35991403,2,0,,8.00E-06,Q92618,Zinc finger protein 516,Zinc finger protein 516,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN516_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cold [GO:0009409]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]" comp122582_c0_seq2,1042,35.7006,0.27335494,13,10,,2.00E-08,Q14590,Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6),Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN235_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122590_c0_seq2,1271,42.9583,0.97707762,31,101,,,,,,,,,5.00E-15,CHOYP_THAPSDRAFT_22560.1.1,,,,,,,,, comp122596_c1_seq1,1314,42.3135,0.32762935,60,189,,0,Q5E9H5,Mitochondrial chaperone BCS1 (BCS1-like protein),Mitochondrial chaperone BCS1 (BCS1-like protein),GO:0005524; GO:0016021; GO:0005743; GO:0032981; GO:0034551; GO:0033617; GO:0017111,ATP binding; integral to membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex I assembly; mitochondrial respiratory chain complex III assembly; mitochondrial respiratory chain complex IV assembly; nucleoside-triphosphatase activity,PF00004;PF08740;,2.00E-96,CHOYP_BCS1.1.1,,,,,,,BCS1_BOVIN,Bos taurus (Bovine),mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex III assembly [GO:0034551]; mitochondrial respiratory chain complex IV assembly [GO:0033617] comp122605_c0_seq1,528,41.8561,0.4918868,22,29,,1.00E-12,Q69ZR9,Protein FAM208A,Protein TASOR (Transgene activation suppressor protein),,,PF12509;,,,,,,,,,F208A_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122613_c2_seq1,970,39.6907,0.36756474,31,86,,4.00E-21,Q13309,S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2),S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2),GO:0000082; GO:0000086; GO:0019005; GO:0031145; GO:0008283; GO:0071460; GO:0005829; GO:0005654; GO:0033148; GO:0048661; GO:0000209; GO:0051726; GO:0004842,G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; SCF ubiquitin ligase complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell proliferation; cellular response to cell-matrix adhesion; cytosol; nucleoplasm; positive regulation of intracellular estrogen receptor signaling pathway; positive regulation of smooth muscle cell proliferation; protein polyubiquitination; regulation of cell cycle; ubiquitin-protein ligase activity,PF12937;,,,,,,,,,SKP2_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell proliferation [GO:0008283]; cellular response to cell-matrix adhesion [GO:0071460]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726] comp122621_c0_seq1,1106,42.1338,0.35005609,48,68,,8.00E-91,Q7ZVK3,NAD-dependent protein deacetylase sirtuin-2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2),NAD-dependent protein deacetylase sirtuin-2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2),GO:0070403; GO:0005737; GO:0016811; GO:0006476; GO:0008270,"NAD+ binding; cytoplasm; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; protein deacetylation; zinc ion binding",PF02146;,2.00E-51,CHOYP_LOC100744089.1.1,5.00E-18,ruditapes_c20047,,,,,SIR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to caloric restriction [GO:0061433]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cilium morphogenesis [GO:0060271]; histone H4 deacetylation [GO:0070933]; negative regulation of autophagy [GO:0010507]; negative regulation of cell proliferation [GO:0008285]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell cycle [GO:0051726]; tubulin deacetylation [GO:0090042] comp122622_c1_seq2,642,40.0312,0.35047323,2,50,,6.00E-63,A2VDF0,Fucose mutarotase (EC 5.1.3.n2),Fucose mutarotase (EC 5.1.3.29),GO:0042806; GO:0006004; GO:0016857,"fucose binding; fucose metabolic process; racemase and epimerase activity, acting on carbohydrates and derivatives",PF05025;,7.00E-29,CHOYP_LOC100377200.2.2,2.00E-78,ruditapes_c24798,,,,,FUCM_HUMAN,Homo sapiens (Human),female mating behavior [GO:0060180]; fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; negative regulation of neuron differentiation [GO:0045665] comp122625_c0_seq1,1118,38.0143,0.44945812,102,0,,5.00E-15,Q10484,Uncharacterized protein C17C9.12,Uncharacterized protein C17C9.12,GO:0005829; GO:0006020; GO:0030176; GO:0008654; GO:0005198,cytosol; inositol metabolic process; integral to endoplasmic reticulum membrane; phospholipid biosynthetic process; structural molecule activity,PF00635;,,,,,,,,,YDFC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),maintenance of ER location [GO:0051685]; phospholipid biosynthetic process [GO:0008654] comp122625_c0_seq2,1610,39.0683,0.3927354,51,54,,3.00E-77,Q9CWP6,Motile sperm domain-containing protein 2,Motile sperm domain-containing protein 2,GO:0016021; GO:0005198,integral to membrane; structural molecule activity,PF00650;PF00635;,2.00E-33,CHOYP_LOC100373427.1.1,,,,,,,MSPD2_MOUSE,Mus musculus (Mouse), comp122633_c0_seq1,1303,38.7567,0.43466692,2462,13801,,6.00E-147,P60901,Proteasome subunit alpha type-6 (EC 3.4.25.1) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain),Proteasome subunit alpha type-6 (EC 3.4.25.1) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain),GO:0003723; GO:0000932; GO:0016363; GO:0005844; GO:0051092; GO:0019773; GO:0051603; GO:0030017; GO:0004298; GO:0006511,"RNA binding; cytoplasmic mRNA processing body; nuclear matrix; polysome; positive regulation of NF-kappaB transcription factor activity; proteasome core complex, alpha-subunit complex; proteolysis involved in cellular protein catabolic process; sarcomere; threonine-type endopeptidase activity; ubiquitin-dependent protein catabolic process",PF00227;PF10584;,7.00E-140,CHOYP_PSA6.1.1,2.00E-125,ruditapes2_c2333,,,,,PSA6_RAT,Rattus norvegicus (Rat),positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin-dependent protein catabolic process [GO:0006511] comp122635_c0_seq1,941,41.7641,0.51328548,48672,112121,,4.00E-83,Q963B7,60S ribosomal protein L9,60S ribosomal protein L9,GO:0019843; GO:0005840; GO:0003735; GO:0006412,rRNA binding; ribosome; structural constituent of ribosome; translation,PF00347;,1.00E-65,CHOYP_RL9.4.6,1.00E-125,ruditapes_lrc12381,,,,,RL9_SPOFR,Spodoptera frugiperda (Fall armyworm),translation [GO:0006412] comp122637_c0_seq1,1448,33.9779,0.47142146,998,7365,,4.00E-33,Q5RA31,Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20),Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20),GO:0015450; GO:0016021; GO:0005742; GO:0006626,P-P-bond-hydrolysis-driven protein transmembrane transporter activity; integral to membrane; mitochondrial outer membrane translocase complex; protein targeting to mitochondrion,PF02064;,,,1.00E-90,ruditapes_c16402,,,,,TOM20_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein targeting to mitochondrion [GO:0006626] comp122641_c0_seq1,293,40.6143,0.91667734,6,25,,4.00E-23,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,3.00E-16,CHOYP_LOC100533356.3.6,,,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp122643_c0_seq1,739,37.4831,0.77204106,430,4399,,7.00E-19,Q8HXX6,Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),GO:0016787; GO:0005764; GO:0006665,hydrolase activity; lysosome; sphingolipid metabolic process,PF02221;,,,,,,,,,SAP3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),ganglioside catabolic process [GO:0006689] comp122655_c0_seq1,1857,39.0953,0.43776471,74,415,,4.00E-59,Q96LT7,Protein C9orf72,Protein C9orf72,GO:0008219; GO:0005737; GO:0005634,cell death; cytoplasm; nucleus,PF15019;,,,,,,,,,CI072_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; endocytosis [GO:0006897] comp122659_c1_seq3,618,44.4984,0.47097949,32,1,,9.00E-72,Q6DCP1,FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-),FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-),GO:0016021; GO:0016491,integral to membrane; oxidoreductase activity,PF01266;,3.00E-26,CHOYP_CPIPJ_CPIJ004840.1.1,,,,,,,FXRD1_XENLA,Xenopus laevis (African clawed frog),mitochondrial respiratory chain complex I assembly [GO:0032981] comp122663_c1_seq1,600,49.3333,0.52537528,5,96,,4.00E-25,Q9Y566,SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP),SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP),GO:0030160; GO:0017146; GO:0017124; GO:0071532; GO:0008306; GO:0030054; GO:0005737; GO:0007016; GO:0060997; GO:0050894; GO:0060076; GO:0046959; GO:0042802; GO:0035255; GO:0007616; GO:0032232; GO:0050885; GO:0097481; GO:0042048; GO:0060999; GO:2000463; GO:0045211; GO:0008022; GO:0006461; GO:0032403; GO:0035418; GO:2000311; GO:0060013; GO:0097110; GO:0035176; GO:0031877; GO:0060074; GO:0071625,GKAP/Homer scaffold activity; N-methyl-D-aspartate selective glutamate receptor complex; SH3 domain binding; ankyrin repeat binding; associative learning; cell junction; cytoplasm; cytoskeletal anchoring at plasma membrane; dendritic spine morphogenesis; determination of affect; excitatory synapse; habituation; identical protein binding; ionotropic glutamate receptor binding; long-term memory; negative regulation of actin filament bundle assembly; neuromuscular process controlling balance; neuronal postsynaptic density; olfactory behavior; positive regulation of dendritic spine development; positive regulation of excitatory postsynaptic membrane potential; postsynaptic membrane; protein C-terminus binding; protein complex assembly; protein complex binding; protein localization to synapse; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; righting reflex; scaffold protein binding; social behavior; somatostatin receptor binding; synapse maturation; vocalization behavior,PF12796;PF16511;PF00595;PF00536;PF07653;,2.00E-59,CHOYP_SHANK2.1.1,,,,,,,SHAN1_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; associative learning [GO:0008306]; cytoskeletal anchoring at plasma membrane [GO:0007016]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein complex assembly [GO:0006461]; protein localization to synapse [GO:0035418]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse maturation [GO:0060074]; vocalization behavior [GO:0071625] comp122681_c0_seq1,665,39.6992,0.41113742,10,30,,2.00E-37,Q6GN42,Choline transporter-like protein 4 (Solute carrier family 44 member 4),Choline transporter-like protein 4 (Solute carrier family 44 member 4),GO:0016021,integral to membrane,PF04515;,3.00E-20,CHOYP_CTL4.1.1,,,,,,,CTL4_XENLA,Xenopus laevis (African clawed frog), comp122682_c0_seq1,201,49.7512,0.85740662,4,69,,,,,,,,,1.00E-26,CHOYP_contig_009415,,,,,,,,, comp122686_c1_seq1,249,42.9719,0.8176004,9,19,,1.00E-07,P52840,Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4) (Sulfokinase),Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4) (Sulfokinase),GO:0004062; GO:0005737; GO:0000166; GO:0008202; GO:0008146,aryl sulfotransferase activity; cytoplasm; nucleotide binding; steroid metabolic process; sulfotransferase activity,PF00685;,,,,,,,,,ST1A1_MOUSE,Mus musculus (Mouse),steroid metabolic process [GO:0008202]; sulfation [GO:0051923] comp122686_c1_seq2,237,36.7089,0.90742356,3,8,,,,,,,,,,,4.00E-11,ruditapes_c21958,,,,,,, comp122687_c0_seq1,1542,37.6783,0.9345078,49,192,,2.00E-20,Q9NDM2,Protein trapped in endoderm-1,Protein trapped in endoderm-1,GO:0004930; GO:0005938; GO:0007281; GO:0035234; GO:0016021; GO:0005886; GO:0007280,G-protein coupled receptor activity; cell cortex; germ cell development; germ cell programmed cell death; integral to membrane; plasma membrane; pole cell migration,PF00001;,2.00E-22,CHOYP_LOC100905010.1.1,,,,,,,GUTR1_DROME,Drosophila melanogaster (Fruit fly),cell surface receptor signaling pathway [GO:0007166]; ectopic germ cell programmed cell death [GO:0035234]; germ cell development [GO:0007281]; germ cell migration [GO:0008354]; G-protein coupled receptor signaling pathway [GO:0007186]; pole cell migration [GO:0007280] comp122689_c0_seq1,653,47.3201,0.46577403,42,1,,4.00E-13,Q8IZJ3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,GO:0005615; GO:0010951; GO:0005886; GO:0004867,extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;,,,,,,,,,CPMD8_HUMAN,Homo sapiens (Human), comp122696_c1_seq1,383,49.0862,0.60849311,16,3,,4.00E-08,Q70CQ2,Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),GO:0016055; GO:0004197; GO:0090263; GO:0071108; GO:0004221; GO:0006511; GO:0004843,Wnt receptor signaling pathway; cysteine-type endopeptidase activity; positive regulation of canonical Wnt receptor signaling pathway; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,3.00E-36,CHOYP_UBP34.1.1,,,,,,,UBP34_HUMAN,Homo sapiens (Human),"histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]" comp122703_c1_seq2,449,38.7528,0.65476515,7,2,,4.00E-13,A5PJF4,Transmembrane protein 218,Transmembrane protein 218,GO:0016021,integral to membrane,,,,,,,,,,TM218_BOVIN,Bos taurus (Bovine), comp122710_c0_seq1,836,41.866,1.0133518,3,7,,9.00E-14,Q91653,Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP),Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP),GO:0005576,extracellular region,PF05428;,,,,,,,,,CRHBP_XENLA,Xenopus laevis (African clawed frog), comp122710_c0_seq2,859,41.7928,1.0419399,9,16,,,,,,,,,,,9.00E-46,ruditapes_c12308,,,,,,, comp122710_c2_seq1,328,40.2439,0.76387987,10,30,,,,,,,,,,,8.00E-16,ruditapes_c11432,,,,,,, comp122716_c0_seq1,529,49.1493,0.43999208,0,0,,1.00E-17,D3Z750,Maestro heat-like repeat-containing protein family member 2A (HEAT repeat-containing protein 7B1),Maestro heat-like repeat-containing protein family member 2A (HEAT repeat-containing protein 7B1),,,,,,,,,,,,HTRB1_MOUSE,Mus musculus (Mouse), comp122716_c0_seq2,700,46.4286,0.40464179,11,8,,3.00E-58,Q54F23,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog),,,,9.00E-72,CHOYP_MROH1.1.1,,,,,,,HTR7A_DICDI,Dictyostelium discoideum (Slime mold), comp122721_c0_seq1,1080,38.3333,0.98472511,117,721,,7.00E-10,Q66I68,Cornifelin homolog,Cornifelin homolog,,,PF04749;,,,6.00E-36,ruditapes_c17439,,,,,CNFN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp122744_c0_seq1,484,45.0413,0.6987318,14,27,,4.00E-13,O15374,Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT5_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp122744_c1_seq1,346,43.6416,0.91509203,1,2,,7.00E-08,O15403,Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6),Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,2.00E-12,CHOYP_DANA_MCT1.1.1,,,,,,,MOT7_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp122759_c0_seq1,828,36.8357,0.8555224,3,158,,4.00E-31,Q03412,Innexin unc-7 (Uncoordinated protein 7),Innexin unc-7 (Uncoordinated protein 7),GO:0005921; GO:0016264; GO:0055077; GO:0016021; GO:0034220; GO:0040011; GO:0032589; GO:0018991; GO:0043051; GO:0042221,gap junction; gap junction assembly; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; locomotion; neuron projection membrane; oviposition; regulation of pharyngeal pumping; response to chemical stimulus,PF00876;,8.00E-17,CHOYP_LOC100533354.2.6,5.00E-23,ruditapes_c18123,,,,,UNC7_CAEEL,Caenorhabditis elegans,gap junction assembly [GO:0016264]; ion transmembrane transport [GO:0034220]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of pharyngeal pumping [GO:0043051]; response to anesthetic [GO:0072347] comp122764_c0_seq1,807,38.0421,1.39190567,583,31937,,,,,,,,,,,4.00E-30,ruditapes_c875,,,,,,, comp122801_c0_seq1,226,44.6903,0.81073016,42,100,,1.00E-14,P97924,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0007409; GO:0005856; GO:0005085; GO:0035556; GO:0046872; GO:0043005; GO:0043025; GO:0048471; GO:0005543; GO:0004674; GO:0035023; GO:0050773,ATP binding; Rho guanyl-nucleotide exchange factor activity; axonogenesis; cytoskeleton; guanyl-nucleotide exchange factor activity; intracellular signal transduction; metal ion binding; neuron projection; neuronal cell body; perinuclear region of cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of dendrite development,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,1.00E-19,CHOYP_KALRN.2.2,,,,,,,KALRN_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023] comp122804_c0_seq1,583,39.6226,0.39418145,15,40,,2.00E-06,Q571B6,"WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1)","WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1)",GO:0005794; GO:0030659; GO:0005793,Golgi apparatus; cytoplasmic vesicle membrane; endoplasmic reticulum-Golgi intermediate compartment,PF15871;PF02205;PF15920;,,,,,,,,,WHAMM_MOUSE,Mus musculus (Mouse),actin filament organization [GO:0007015]; actin filament reorganization [GO:0090527]; ER to Golgi vesicle-mediated transport [GO:0006888]; focal adhesion assembly [GO:0048041]; lamellipodium assembly [GO:0030032]; membrane tubulation [GO:0097320]; positive regulation of actin nucleation [GO:0051127] comp122807_c0_seq2,344,41.5698,1.85485438,3,0,,,,,,,,,,,1.00E-19,ruditapes_c18369,,,,,,, comp122809_c0_seq1,529,48.0151,0.29723436,3,0,,5.00E-80,Q9VXY2,MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor),MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor),GO:0017112; GO:0000187; GO:0006915; GO:0016021; GO:0007269; GO:0051726; GO:1902041; GO:0008021; GO:0016192,Rab guanyl-nucleotide exchange factor activity; activation of MAPK activity; apoptotic process; integral to membrane; neurotransmitter secretion; regulation of cell cycle; regulation of extrinsic apoptotic signaling pathway via death domain receptors; synaptic vesicle; vesicle-mediated transport,PF02141;PF03456;,,,,,,,,,MADD_DROME,Drosophila melanogaster (Fruit fly),activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; neurotransmitter secretion [GO:0007269]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; vesicle-mediated transport [GO:0016192] comp122809_c0_seq2,590,48.3051,0.3201526,6,0,,6.00E-95,Q9VXY2,MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor),MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor),GO:0017112; GO:0000187; GO:0006915; GO:0016021; GO:0007269; GO:0051726; GO:1902041; GO:0008021; GO:0016192,Rab guanyl-nucleotide exchange factor activity; activation of MAPK activity; apoptotic process; integral to membrane; neurotransmitter secretion; regulation of cell cycle; regulation of extrinsic apoptotic signaling pathway via death domain receptors; synaptic vesicle; vesicle-mediated transport,PF02141;PF03456;,1.00E-113,CHOYP_MADD.2.3,,,,,,,MADD_DROME,Drosophila melanogaster (Fruit fly),activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; neurotransmitter secretion [GO:0007269]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; vesicle-mediated transport [GO:0016192] comp122809_c1_seq1,315,41.9048,0.58900873,17,0,,,,,,,,,1.00E-21,CHOYP_MADD.3.3,,,,,,,,, comp122817_c0_seq1,1826,41.7853,0.52834024,68,82,,1.00E-37,Q9JIM1,"Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)","Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)",GO:0016324; GO:0016323; GO:0016021; GO:0005337; GO:0015858,apical plasma membrane; basolateral plasma membrane; integral to membrane; nucleoside transmembrane transporter activity; nucleoside transport,PF01733;,2.00E-21,CHOYP_MPI.1.1,,,,,,,S29A1_MOUSE,Mus musculus (Mouse),cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; excitatory postsynaptic potential [GO:0060079]; lactation [GO:0007595]; nucleoside transport [GO:0015858]; sleep [GO:0030431]; uridine transport [GO:0015862] comp122819_c2_seq1,955,45.1309,0.50052411,34,62,,1.00E-38,P11533,Dystrophin,Dystrophin,GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0045211; GO:0042383; GO:0008270,calcium ion binding; cell junction; cytoplasm; cytoskeleton; postsynaptic membrane; sarcolemma; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;,7.00E-31,CHOYP_DLP.1.1,,,,,,,DMD_CHICK,Gallus gallus (Chicken),muscle attachment [GO:0016203] comp122822_c0_seq1,1128,32.8901,0.50978366,3577,8329,,2.00E-17,P90789,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7,GO:0008137; GO:0005743; GO:0005758; GO:0070469,NADH dehydrogenase (ubiquinone) activity; mitochondrial inner membrane; mitochondrial intermembrane space; respiratory chain,PF05676;,,,,,,,,,NDUB7_CAEEL,Caenorhabditis elegans, comp122827_c1_seq2,1462,42.2709,0.59167759,0,0,,6.00E-09,D6PXE8,Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP),Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP),GO:0005576; GO:0004222; GO:0006508; GO:0008270,extracellular region; metalloendopeptidase activity; proteolysis; zinc ion binding,PF08516;PF01562;PF01421;,,,,,,,,,VM3B_NAJAT,Naja atra (Chinese cobra), comp122827_c1_seq3,1590,42.8302,0.51781274,3,0,,2.00E-107,O14672,Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c),Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c),GO:0005798; GO:0007220; GO:0007219; GO:0051088; GO:0009986; GO:0007267; GO:0030574; GO:0051089; GO:0012505; GO:0007173; GO:0022617; GO:0001701; GO:0016021; GO:0005178; GO:0007229; GO:0004222; GO:0042117; GO:0007162; GO:0005634; GO:0005886; GO:0010820; GO:0030307; GO:0008284; GO:0014069; GO:0042803; GO:0019901; GO:0006468; GO:0034612; GO:0008270,Golgi-associated vesicle; Notch receptor processing; Notch signaling pathway; PMA-inducible membrane protein ectodomain proteolysis; cell surface; cell-cell signaling; collagen catabolic process; constitutive protein ectodomain proteolysis; endomembrane system; epidermal growth factor receptor signaling pathway; extracellular matrix disassembly; in utero embryonic development; integral to membrane; integrin binding; integrin-mediated signaling pathway; metalloendopeptidase activity; monocyte activation; negative regulation of cell adhesion; nucleus; plasma membrane; positive regulation of T cell chemotaxis; positive regulation of cell growth; positive regulation of cell proliferation; postsynaptic density; protein homodimerization activity; protein kinase binding; protein phosphorylation; response to tumor necrosis factor; zinc ion binding,PF00200;PF01562;,1.00E-42,CHOYP_LOC100117425.1.1,,,,,,,ADA10_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; constitutive protein ectodomain proteolysis [GO:0051089]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; response to tumor necrosis factor [GO:0034612] comp122831_c1_seq2,1269,41.9228,0.73373339,54,3,,2.00E-109,Q8BH18,Transmembrane protein 117,Transmembrane protein 117,GO:0005783; GO:0016021,endoplasmic reticulum; integral to membrane,PF15113;,5.00E-72,CHOYP_BRAFLDRAFT_236042.1.1,,,,,,,TM117_MOUSE,Mus musculus (Mouse), comp122837_c1_seq1,889,38.6952,0.53766948,38,25,,1.00E-49,Q5F415,TBC1 domain family member 23,TBC1 domain family member 23,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF00581;,8.00E-49,CHOYP_LOC100375955.1.1,,,,,,,TBC23_CHICK,Gallus gallus (Chicken), comp12283_c0_seq1,292,42.8082,0.45497428,2,0,,6.00E-20,Q5PR34,Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (Solute carrier family 7 member 2),Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2),GO:0015171; GO:0016021,amino acid transmembrane transporter activity; integral to membrane,PF13520;PF13906;,,,,,,,,,CTR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp122843_c0_seq1,822,34.5499,0.57876316,18463,22018,,3.00E-17,Q9W141,"Putative ATP synthase subunit f, mitochondrial","Putative ATP synthase subunit f, mitochondrial",GO:0006754; GO:0046331; GO:0005811; GO:0031966; GO:0015992; GO:0045263,"ATP biosynthetic process; lateral inhibition; lipid particle; mitochondrial membrane; proton transport; proton-transporting ATP synthase complex, coupling factor F(o)",PF10206;,,,,,,,,,ATPK_DROME,Drosophila melanogaster (Fruit fly),ATP biosynthetic process [GO:0006754]; lateral inhibition [GO:0046331]; proton transport [GO:0015992] comp122844_c0_seq1,770,42.987,0.42310015,28,28,,4.00E-83,Q9BYN7,Zinc finger protein 341,Zinc finger protein 341,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,3.00E-53,CHOYP_ZN341.1.1,,,,,,,ZN341_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122844_c0_seq2,226,42.4779,0.68998311,0,6,,8.00E-13,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp122860_c1_seq2,573,41.7103,0.64639837,15,9,,4.00E-08,Q767L8,Mediator of DNA damage checkpoint protein 1,Mediator of DNA damage checkpoint protein 1,GO:0006281; GO:0007049; GO:0005694; GO:0005634,DNA repair; cell cycle; chromosome; nucleus,PF00498;PF16770;,,,,,,,,,MDC1_PIG,Sus scrofa (Pig),cell cycle [GO:0007049]; DNA repair [GO:0006281] comp122860_c2_seq1,615,45.6911,0.69390864,11,11,,7.00E-32,A0JNA8,PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),GO:0006310; GO:0006281; GO:0016363; GO:0006355; GO:0006351,"DNA recombination; DNA repair; nuclear matrix; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00533;PF12738;PF16770;,,,,,,,,,PAXI1_BOVIN,Bos taurus (Bovine),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122862_c0_seq1,694,42.6513,0.44946509,21,65,,3.00E-26,Q9DBY5,Chromobox protein homolog 6,Chromobox protein homolog 6,GO:0031519; GO:0016568; GO:0000792; GO:0000122; GO:0003727; GO:0006351,"PcG protein complex; chromatin modification; heterochromatin; negative regulation of transcription from RNA polymerase II promoter; single-stranded RNA binding; transcription, DNA-dependent",PF00385;,1.00E-19,CHOYP_ISCW_ISCW012843.1.1,,,,,,,CBX6_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp122865_c1_seq1,833,45.018,0.99670073,7707,68844,,1.00E-127,P02552,Tubulin alpha-1 chain (Fragment),Tubulin alpha-1 chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,2.00E-158,CHOYP_TBA1A.1.4,8.00E-160,ruditapes2_lrc3246,,,,,TBA1_CHICK,Gallus gallus (Chicken),microtubule-based process [GO:0007017] comp122865_c2_seq1,778,50.5141,1.03133445,3387,40278,,6.00E-133,P18258,Tubulin alpha-1 chain,Tubulin alpha-1 chain,GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,7.00E-144,CHOYP_DERE_GG14119.1.1,5.00E-99,ruditapes_c24684,,,,,TBA1_PARLI,Paracentrotus lividus (Common sea urchin),microtubule-based process [GO:0007017] comp122873_c0_seq1,237,47.2574,0.48130281,8,6,,9.00E-13,D3Z5T1,Coiled-coil domain-containing protein 78,Coiled-coil domain-containing protein 78,GO:0048471; GO:0042383; GO:0016529; GO:0003009,perinuclear region of cytoplasm; sarcolemma; sarcoplasmic reticulum; skeletal muscle contraction,PF14739;,,,,,,,,,CCD78_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; de novo centriole assembly [GO:0098535]; skeletal muscle contraction [GO:0003009] comp122873_c0_seq3,718,44.7075,0.49747756,2,0,,1.00E-11,A2IDD5,Coiled-coil domain-containing protein 78 (hsCCDC78),Coiled-coil domain-containing protein 78 (hsCCDC78),GO:0048471; GO:0042383; GO:0016529; GO:0003009,perinuclear region of cytoplasm; sarcolemma; sarcoplasmic reticulum; skeletal muscle contraction,PF14739;,2.00E-11,CHOYP_BRAFLDRAFT_75956.1.1,,,,,,,CCD78_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; de novo centriole assembly [GO:0098535]; skeletal muscle contraction [GO:0003009] comp122874_c0_seq1,447,44.7427,0.31616249,6,18,,2.00E-17,Q5W4S4,Folliculin-interacting protein 1,Folliculin-interacting protein 1,GO:0031929; GO:0009267; GO:0005737; GO:0005085; GO:0002327; GO:0032007; GO:0043154; GO:0000122; GO:0002904; GO:0033138; GO:2000973,TOR signaling cascade; cellular response to starvation; cytoplasm; guanyl-nucleotide exchange factor activity; immature B cell differentiation; negative regulation of TOR signaling cascade; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of B cell apoptotic process; positive regulation of peptidyl-serine phosphorylation; regulation of pro-B cell differentiation,PF14638;PF14637;PF14636;,5.00E-16,CHOYP_FNIP1.1.1,,,,,,,FNIP1_CHICK,Gallus gallus (Chicken),cellular response to starvation [GO:0009267]; immature B cell differentiation [GO:0002327]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; regulation of pro-B cell differentiation [GO:2000973]; TOR signaling [GO:0031929] comp122874_c0_seq2,267,49.4382,0.30769662,0,0,,2.00E-13,Q80TD3,Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein),Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein),GO:0005737; GO:0008630; GO:0000122; GO:0005634; GO:0005886; GO:0033138; GO:0006468,cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of transcription from RNA polymerase II promoter; nucleus; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein phosphorylation,PF14638;PF14637;PF14636;,,,,,,,,,FNIP2_MOUSE,Mus musculus (Mouse),intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] comp122875_c0_seq1,418,63.3971,0.99209392,0,65,,2.00E-22,Q9C3Z5,60S acidic ribosomal protein P2,60S acidic ribosomal protein P2,GO:0005840; GO:0003735; GO:0006414,ribosome; structural constituent of ribosome; translational elongation,,,,,,,,,,RLA2_PODAS,Podospora anserina (Pleurage anserina),translational elongation [GO:0006414] comp122880_c0_seq1,373,40.7507,0.72750302,23,3,,4.00E-39,P97694,"Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog A) (rSec7-1)","Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog A) (rSec7-1)",GO:0005086; GO:0005737; GO:0005543; GO:0005886; GO:0032012; GO:0030155,ARF guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; plasma membrane; regulation of ARF protein signal transduction; regulation of cell adhesion,PF00169;PF01369;,,,,,,,,,CYH1_RAT,Rattus norvegicus (Rat),regulation of ARF protein signal transduction [GO:0032012] comp122880_c1_seq5,651,42.3963,0.24148205,1,0,,5.00E-95,Q9Y6D5,Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2),Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2),GO:0005086; GO:0050811; GO:0000139; GO:0006893; GO:0032279; GO:0005879; GO:0030054; GO:0016023; GO:0031410; GO:0005829; GO:0043197; GO:0010256; GO:0007032; GO:0006887; GO:0035556; GO:0005815; GO:0048471; GO:0032760; GO:0034237; GO:0015031; GO:0001881; GO:0055037; GO:0032012; GO:0032280; GO:0005802,ARF guanyl-nucleotide exchange factor activity; GABA receptor binding; Golgi membrane; Golgi to plasma membrane transport; asymmetric synapse; axonemal microtubule; cell junction; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; dendritic spine; endomembrane system organization; endosome organization; exocytosis; intracellular signal transduction; microtubule organizing center; perinuclear region of cytoplasm; positive regulation of tumor necrosis factor production; protein kinase A regulatory subunit binding; protein transport; receptor recycling; recycling endosome; regulation of ARF protein signal transduction; symmetric synapse; trans-Golgi network,PF16213;PF09324;PF01369;PF12783;,3.00E-103,CHOYP_BIG1.3.3,,,,,,,BIG2_HUMAN,Homo sapiens (Human),endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012] comp122882_c0_seq1,497,35.4125,0.45491506,10,49,,1.00E-26,Q24732,Protein glass,Protein glass,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0050896; GO:0006351; GO:0007601,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; response to stimulus; transcription, DNA-dependent; visual perception",PF00096;,,,,,,,,,GLAS_DROVI,Drosophila virilis (Fruit fly),"regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp122898_c0_seq1,773,38.2924,1.3502295,33,118,,6.00E-06,P56719,Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2),Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2),GO:0022410; GO:0007631; GO:0016021; GO:0007218; GO:0016499; GO:0017046; GO:0007200; GO:0005886,circadian sleep/wake cycle process; feeding behavior; integral to membrane; neuropeptide signaling pathway; orexin receptor activity; peptide hormone binding; phospholipase C-activating G-protein coupled receptor signaling pathway; plasma membrane,PF00001;PF03827;,,,,,,,,,OX2R_RAT,Rattus norvegicus (Rat),"cellular response to hormone stimulus [GO:0032870]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G-protein coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to peptide [GO:1901652]" comp122899_c1_seq1,1159,44.0897,0.55442533,35,75,,0,Q9JIT3,Transducin-like enhancer protein 3 (rTLE3),Transducin-like enhancer protein 3 (rTLE3),GO:0016055; GO:0005634; GO:0006355; GO:0006351,"Wnt receptor signaling pathway; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03920;PF00400;,0,CHOYP_TLE4.1.1,,,,,,,TLE3_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp122900_c0_seq1,435,44.5977,0.27948866,26,15,,5.00E-11,Q8NDA8,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),,,PF02985;,,,,,,,,,HTR7A_HUMAN,Homo sapiens (Human), comp122900_c1_seq1,236,46.1864,0.16356401,11,0,,,,,,,,,2.00E-37,CHOYP_MROH1.1.1,,,,,,,,, comp122902_c0_seq1,838,36.0382,0.36798298,43,113,,1.00E-53,Q5XJR6,ORM1-like protein 3,ORM1-like protein 3,GO:0035339; GO:0006672; GO:0016021,SPOTS complex; ceramide metabolic process; integral to membrane,PF04061;,5.00E-19,CHOYP_ORML1.1.1,,,,,,,ORML3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular sphingolipid homeostasis [GO:0090156]; ceramide metabolic process [GO:0006672]; negative regulation of ceramide biosynthetic process [GO:1900060] comp122904_c0_seq2,362,42.2652,0.63218873,23,18,,5.00E-48,Q7SXN5,Dynamin-1-like protein (EC 3.6.5.5),Dynamin-1-like protein (EC 3.6.5.5),GO:0005525; GO:0003924; GO:0005829; GO:0003374; GO:0016020; GO:0000266; GO:0005739; GO:0005777; GO:0042803,GTP binding; GTPase activity; cytosol; dynamin polymerization involved in mitochondrial fission; membrane; mitochondrial fission; mitochondrion; peroxisome; protein homodimerization activity,PF01031;PF00350;PF02212;,1.00E-40,CHOYP_LOC100646574.1.1,,,,,,,DNM1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),dynamin polymerization involved in mitochondrial fission [GO:0003374]; mitochondrial fission [GO:0000266]; peroxisome fission [GO:0016559] comp122913_c0_seq1,1340,43.5075,0.45100922,14,4,,5.00E-34,Q5M9N0,Coiled-coil domain-containing protein 158,Coiled-coil domain-containing protein 158,,,PF15921;,4.00E-23,CHOYP_LOC100373433.1.1,,,,,,,CD158_HUMAN,Homo sapiens (Human), comp122914_c0_seq2,674,45.1039,0.29465754,32,33,,1.00E-96,Q0V8R6,Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha),Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha),GO:0007628; GO:0004563; GO:0005975; GO:0048667; GO:0006689; GO:0030203; GO:0019915; GO:0005764; GO:0007040; GO:0016020; GO:0042552; GO:0050885; GO:0050884; GO:0007605; GO:0019953; GO:0001501,adult walking behavior; beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; cell morphogenesis involved in neuron differentiation; ganglioside catabolic process; glycosaminoglycan metabolic process; lipid storage; lysosome; lysosome organization; membrane; myelination; neuromuscular process controlling balance; neuromuscular process controlling posture; sensory perception of sound; sexual reproduction; skeletal system development,PF00728;PF14845;,1.00E-31,CHOYP_LOC100708717.1.1,,,,,,,HEXA_BOVIN,Bos taurus (Bovine),adult walking behavior [GO:0007628]; carbohydrate metabolic process [GO:0005975]; cell morphogenesis involved in neuron differentiation [GO:0048667]; ganglioside catabolic process [GO:0006689]; glycosaminoglycan metabolic process [GO:0030203]; lipid storage [GO:0019915]; lysosome organization [GO:0007040]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; sensory perception of sound [GO:0007605]; sexual reproduction [GO:0019953]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395] comp122918_c0_seq1,1816,31.9383,0.63749777,56,1210,,,,,,,,,,,3.00E-23,ruditapes2_c1354,,,,,,, comp122923_c1_seq1,611,48.6088,0.68031678,7,81,,1.00E-32,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp122950_c0_seq1,1237,43.8965,0.89081735,2328,13414,,9.00E-131,Q86SK9,Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase),Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase) (Stearoyl-CoA desaturase 2),GO:0005789; GO:0006633; GO:0016021; GO:0005506; GO:0004768,endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; iron ion binding; stearoyl-CoA 9-desaturase activity,PF00487;,6.00E-20,CHOYP_NASP.2.4,3.00E-28,ruditapes_c1509,,,,,SCD5_HUMAN,Homo sapiens (Human),long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; unsaturated fatty acid biosynthetic process [GO:0006636] comp122955_c0_seq1,854,37.3536,0.57147991,1736,15,male>female,7.00E-40,Q5VTT2,Uncharacterized protein C9orf135,Uncharacterized protein C9orf135,GO:0016021,integral to membrane,PF15139;,4.00E-71,CHOYP_LOC580840.1.1,,,,,,,CI135_HUMAN,Homo sapiens (Human), comp122961_c2_seq1,590,31.5254,0.27446961,4,54,,1.00E-06,P10077,Zinc finger protein 27 (Zfp-27) (Protein mKR4),Zinc finger protein 27 (Zfp-27) (Protein mKR4),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZFP27_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122972_c0_seq1,307,40.3909,1.44263826,0,46,,3.00E-06,Q8AWB6,Solute carrier family 35 member B1 (Endoplasmic reticulum nucleotide sugar transporter 1),Solute carrier family 35 member B1 (Endoplasmic reticulum nucleotide sugar transporter 1),GO:0008643; GO:0005789; GO:0016021; GO:0055085,carbohydrate transport; endoplasmic reticulum membrane; integral to membrane; transmembrane transport,PF08449;,,,,,,,,,S35B1_CHICK,Gallus gallus (Chicken),UDP-galactose transmembrane transport [GO:0072334] comp122972_c2_seq2,723,45.5048,0.66888524,0,0,,6.00E-32,Q8WZJ9,UDP-galactose transporter homolog 1,UDP-galactose transporter homolog 1,GO:0005459; GO:0015837; GO:0005783; GO:0005789; GO:0016021; GO:0006886,UDP-galactose transmembrane transporter activity; amine transport; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; intracellular protein transport,PF08449;,,,,,,,,,HUT1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),UDP-galactose transmembrane transport [GO:0072334] comp122972_c2_seq3,769,44.9935,0.66911878,0,0,,3.00E-99,Q8AXS6,Solute carrier family 35 member B1,Solute carrier family 35 member B1,GO:0008643; GO:0005789; GO:0016021; GO:0055085,carbohydrate transport; endoplasmic reticulum membrane; integral to membrane; transmembrane transport,PF08449;,4.00E-71,CHOYP_S35B1.1.1,,,,,,,S35B1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),UDP-galactose transmembrane transport [GO:0072334] comp122972_c2_seq4,638,46.2382,0.647418,0,0,,9.00E-15,P0CP32,UDP-galactose transporter homolog 1,UDP-galactose transporter homolog 1,GO:0008643; GO:0005789; GO:0016021; GO:0055085,carbohydrate transport; endoplasmic reticulum membrane; integral to membrane; transmembrane transport,PF08449;,,,,,,,,,HUT1_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),UDP-galactose transmembrane transport [GO:0072334] comp122977_c0_seq1,460,46.087,0.65933985,7,28,,5.00E-17,B2DFG5,D-threo-3-hydroxyaspartate dehydratase (D-THA DH) (D-THA dehydratase) (EC 4.3.1.27) (Threo-3-hydroxy-D-aspartate ammonia-lyase),D-threo-3-hydroxyaspartate dehydratase (D-THA DH) (D-THA dehydratase) (EC 4.3.1.27) (Threo-3-hydroxy-D-aspartate ammonia-lyase),GO:0016841; GO:0030170,ammonia-lyase activity; pyridoxal phosphate binding,PF01168;PF14031;,,,,,,,,,DTHAD_DELSH,Delftia sp. (strain HT23), comp122978_c0_seq1,760,43.5526,0.41997865,49,22,,3.00E-40,Q3U492,Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1),Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1),GO:0005615; GO:0030513,extracellular space; positive regulation of BMP signaling pathway,PF00093;PF00094;,,,,,,,,,KCP_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244]; positive regulation of BMP signaling pathway [GO:0030513] comp122982_c0_seq1,2396,32.6795,0.28178641,6472,8720,,5.00E-31,Q5R7A8,C-Myc-binding protein (Associate of Myc 1) (AMY-1),C-Myc-binding protein (Associate of Myc 1) (AMY-1),GO:0005813; GO:0005737; GO:0005634; GO:0006355; GO:0007283; GO:0003713; GO:0006351,"centrosome; cytoplasm; nucleus; regulation of transcription, DNA-dependent; spermatogenesis; transcription coactivator activity; transcription, DNA-dependent",,5.00E-50,CHOYP_LOC100369611.1.1,1.00E-73,ruditapes_c2013,,,,,MYCBP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp122984_c0_seq3,1371,44.566,0.32605284,0,0,,1.00E-176,Q8BGT5,Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2),Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2),GO:0006103; GO:0042853; GO:0042851; GO:0004021; GO:0009058; GO:0005739; GO:0030170,2-oxoglutarate metabolic process; L-alanine catabolic process; L-alanine metabolic process; L-alanine:2-oxoglutarate aminotransferase activity; biosynthetic process; mitochondrion; pyridoxal phosphate binding,PF00155;,0,CHOYP_ALAT2.1.1,,,,,,,ALAT2_MOUSE,Mus musculus (Mouse),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] comp122984_c0_seq6,1195,44.0167,0.34897317,0,0,,1.00E-12,Q9MB95,1-aminocyclopropane-1-carboxylate synthase 1 (ACC synthase 1) (EC 4.4.1.14) (S-adenosyl-L-methionine methylthioadenosine-lyase),1-aminocyclopropane-1-carboxylate synthase 1 (ACC synthase 1) (EC 4.4.1.14) (S-adenosyl-L-methionine methylthioadenosine-lyase),GO:0042218; GO:0016847; GO:0009693; GO:0009835; GO:0030170,1-aminocyclopropane-1-carboxylate biosynthetic process; 1-aminocyclopropane-1-carboxylate synthase activity; ethylene biosynthetic process; fruit ripening; pyridoxal phosphate binding,PF00155;,3.00E-156,CHOYP_ALAT2.1.1,,,,,,,1A11_PRUMU,Prunus mume (Japanese apricot) (Armeniaca mume),ethylene biosynthetic process [GO:0009693]; fruit ripening [GO:0009835] comp122986_c0_seq1,550,48,0.34803446,14,20,,4.00E-61,Q9NVE7,Pantothenate kinase 4 (hPanK4) (EC 2.7.1.33) (Pantothenic acid kinase 4),Pantothenate kinase 4 (hPanK4) (EC 2.7.1.33) (Pantothenic acid kinase 4),GO:0005524; GO:0015937; GO:0005737; GO:0004594,ATP binding; coenzyme A biosynthetic process; cytoplasm; pantothenate kinase activity,PF01937;PF03630;,2.00E-80,CHOYP_BRAFLDRAFT_72760.1.1,,,,,,,PANK4_HUMAN,Homo sapiens (Human),coenzyme A biosynthetic process [GO:0015937] comp122996_c0_seq1,468,44.4444,1.08414734,22,117,,1.00E-31,Q91Z53,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0005737; GO:0007588; GO:0008465; GO:0030267; GO:0016618; GO:0051259,NAD binding; NADPH binding; cytoplasm; excretion; glycerate dehydrogenase activity; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; protein oligomerization,PF00389;PF02826;,,,,,,,,,GRHPR_MOUSE,Mus musculus (Mouse),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp123000_c0_seq1,1455,41.7182,1.13026228,352,4573,,,,,,,,,,,3.00E-41,ruditapes2_lrc6044,,,,,,, comp123000_c0_seq2,1414,44.6959,1.10746594,644,13117,,4.00E-21,P37801,Calponin homolog OV9M,Calponin homolog OV9M,,,PF00402;,,,8.00E-49,ruditapes2_c3343,,,,,CLPH_ONCVO,Onchocerca volvulus, comp123000_c0_seq3,502,37.8486,1.13595753,124,1520,,7.00E-08,Q08094,"Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) (Fragment)","Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) (Fragment)",GO:0031032,actomyosin structure organization,PF00402;PF00307;,,,,,,,,,CNN2_PIG,Sus scrofa (Pig),actomyosin structure organization [GO:0031032] comp123009_c0_seq1,585,40,0.42921095,13,0,,6.00E-15,O35231,Kinesin-like protein KIFC3,Kinesin-like protein KIFC3,GO:0005524; GO:0005794; GO:0007030; GO:0005813; GO:0030659; GO:0090136; GO:0005871; GO:0005874; GO:0007018; GO:0007017; GO:0008569; GO:0005915; GO:0045218,ATP binding; Golgi apparatus; Golgi organization; centrosome; cytoplasmic vesicle membrane; epithelial cell-cell adhesion; kinesin complex; microtubule; microtubule-based movement; microtubule-based process; minus-end-directed microtubule motor activity; zonula adherens; zonula adherens maintenance,PF00225;,,,,,,,,,KIFC3_MOUSE,Mus musculus (Mouse),epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218] comp123009_c0_seq2,564,39.539,0.45712118,0,25,,1.00E-14,Q9BVG8,Kinesin-like protein KIFC3,Kinesin-like protein KIFC3,GO:0005524; GO:0005794; GO:0007030; GO:0005813; GO:0030659; GO:0090136; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007601; GO:0005915; GO:0045218,ATP binding; Golgi apparatus; Golgi organization; centrosome; cytoplasmic vesicle membrane; epithelial cell-cell adhesion; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; visual perception; zonula adherens; zonula adherens maintenance,PF00225;,,,,,,,,,KIFC3_HUMAN,Homo sapiens (Human),epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] comp123009_c1_seq1,495,45.8586,0.73190731,29,37,,1.00E-61,Q9BVG8,Kinesin-like protein KIFC3,Kinesin-like protein KIFC3,GO:0005524; GO:0005794; GO:0007030; GO:0005813; GO:0030659; GO:0090136; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007601; GO:0005915; GO:0045218,ATP binding; Golgi apparatus; Golgi organization; centrosome; cytoplasmic vesicle membrane; epithelial cell-cell adhesion; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; visual perception; zonula adherens; zonula adherens maintenance,PF00225;,7.00E-65,CHOYP_LOC100375065.1.1,,,,,,,KIFC3_HUMAN,Homo sapiens (Human),epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] comp123022_c0_seq1,336,28.2738,0.60286759,11,0,,4.00E-09,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp123022_c1_seq1,399,35.8396,0.47790025,3,27,,,,,,,,,1.00E-17,CHOYP_LOC100562878.2.2,,,,,,,,, comp123022_c1_seq2,333,36.036,0.4702943,9,11,,3.00E-08,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,2.00E-26,CHOYP_LOC100537145.2.3,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp123030_c0_seq1,318,43.7107,0.26583596,4,11,,2.00E-12,Q6ZN80,Putative maltase-glucoamylase-like protein FLJ16351 (EC 3.2.1.-),,GO:0030246; GO:0005975; GO:0004553,"carbohydrate binding; carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds",,,,,,,,,,MGAL1_HUMAN,, comp123030_c1_seq1,629,41.3355,0.41559325,29,34,,2.00E-22,Q9MYM4,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),GO:0030246; GO:0005975; GO:0060048; GO:0005765; GO:0032450; GO:0043587; GO:0043181; GO:0055010,carbohydrate binding; carbohydrate metabolic process; cardiac muscle contraction; lysosomal membrane; maltose alpha-glucosidase activity; tongue morphogenesis; vacuolar sequestering; ventricular cardiac muscle tissue morphogenesis,PF13802;PF01055;PF16863;PF00088;,,,,,,,,,LYAG_BOVIN,Bos taurus (Bovine),cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] comp123031_c0_seq1,787,33.6722,0.36022915,25,110,,9.00E-78,Q9VCA9,Signal peptidase complex subunit 3 (EC 3.4.-.-) (Microsomal signal peptidase 22 kDa subunit) (SPC22) (SPase 22 kDa subunit),Signal peptidase complex subunit 3 (EC 3.4.-.-) (Microsomal signal peptidase 22 kDa subunit) (SPC22) (SPase 22 kDa subunit),GO:0016021; GO:0008233; GO:0006508; GO:0005787; GO:0006465,integral to membrane; peptidase activity; proteolysis; signal peptidase complex; signal peptide processing,PF04573;,3.00E-84,CHOYP_LOC100373371.1.1,,,,,,,SPCS3_DROME,Drosophila melanogaster (Fruit fly),signal peptide processing [GO:0006465] comp123039_c0_seq1,739,42.2192,0.91463582,17,152,,2.00E-09,P0AGE8,Uncharacterized protein YieF,Chromate reductase (CHRR) (EC 1.6.5.2) (NAD(P)H dehydrogenase (quinone)),GO:0016491,oxidoreductase activity,PF03358;,,,,,,,,,YIEF_SHIFL,Shigella flexneri, comp123046_c0_seq2,872,44.7248,0.63390251,49,5,,9.00E-103,Q63054,Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69),Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69),GO:0000139; GO:0005795; GO:0030054; GO:0005829; GO:0030425; GO:0006836; GO:0048471; GO:0019904; GO:0043496; GO:0030667; GO:0030672; GO:0030658,Golgi membrane; Golgi stack; cell junction; cytosol; dendrite; neurotransmitter transport; perinuclear region of cytoplasm; protein domain specific binding; regulation of protein homodimerization activity; secretory granule membrane; synaptic vesicle membrane; transport vesicle membrane,PF06456;PF04629;,2.00E-158,CHOYP_LOC100373653.3.3,,,,,,,ICA69_RAT,Rattus norvegicus (Rat),neurotransmitter transport [GO:0006836]; regulation of insulin secretion [GO:0050796]; regulation of protein homodimerization activity [GO:0043496] comp123053_c0_seq3,943,42.6299,0.3287157,0,0,,3.00E-06,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp123055_c0_seq1,209,44.0191,0.31250715,7,11,,3.00E-07,Q29175,"Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) (Fragments)","Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) (Fragments)",GO:0005794; GO:0005789; GO:0016021; GO:0046873; GO:0006829,Golgi apparatus; endoplasmic reticulum membrane; integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,2.00E-17,CHOYP_NEMVEDRAFT_V1G241132.1.1,,,,,,,S39A7_PIG,Sus scrofa (Pig),zinc II ion transport [GO:0006829] comp123055_c1_seq1,644,47.205,0.81756393,0,13,,1.00E-14,Q9V3A4,Protein catecholamines up,Protein catecholamines up,GO:0030424; GO:0007298; GO:0030234; GO:0016021; GO:0046873; GO:0043025; GO:0007300; GO:0042069; GO:2000274; GO:0008021,"axon; border follicle cell migration; enzyme regulator activity; integral to membrane; metal ion transmembrane transporter activity; neuronal cell body; ovarian nurse cell to oocyte transport; regulation of catecholamine metabolic process; regulation of epithelial cell migration, open tracheal system; synaptic vesicle",PF02535;,,,,,,,,,CSUP_DROME,Drosophila melanogaster (Fruit fly),"border follicle cell migration [GO:0007298]; cellular zinc ion homeostasis [GO:0006882]; ovarian nurse cell to oocyte transport [GO:0007300]; regulation of catecholamine metabolic process [GO:0042069]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; zinc II ion transmembrane transport [GO:0071577]" comp123055_c1_seq2,708,47.3164,0.76171188,5,0,,5.00E-21,Q9PUB8,"Zinc transporter Slc39a7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) (Fragment)","Zinc transporter Slc39a7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) (Fragment)",GO:0005794; GO:0005789; GO:0016021; GO:0046873; GO:0006829,Golgi apparatus; endoplasmic reticulum membrane; integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,,,,,,,,,S39A7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),zinc II ion transport [GO:0006829]; zinc ion homeostasis [GO:0055069] comp123056_c0_seq1,347,65.9942,1.07680996,23,29,,,,,,,,,2.00E-177,CHOYP_RNA45S5.2.4,,,,,,,,, comp123059_c0_seq1,1569,42.5749,0.7043141,59,90,,1.00E-20,Q7Z6M2,F-box only protein 33,F-box only protein 33,GO:0016567,protein ubiquitination,PF12937;,,,,,,,,,FBX33_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp123060_c0_seq1,1015,45.3202,0.62291859,109,78,,5.00E-27,Q9Y5B6,PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1),PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1),GO:0003677; GO:0005829; GO:0007517; GO:0005634; GO:0031062; GO:2000288; GO:0045944; GO:0014842; GO:0006355; GO:0003700; GO:0006351,"DNA binding; cytosol; muscle organ development; nucleus; positive regulation of histone methylation; positive regulation of myoblast proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of satellite cell proliferation; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF07842;,8.00E-24,CHOYP_PAXB1.1.2,,,,,,,GCFC1_HUMAN,Homo sapiens (Human),"muscle organ development [GO:0007517]; positive regulation of histone methylation [GO:0031062]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription, DNA-templated [GO:0006351]" comp123073_c0_seq1,354,37.0056,0.42464454,0,0,,4.00E-06,P81712,Subtilisin inhibitor CLSI-I,Subtilisin inhibitor CLSI-I,GO:0009611; GO:0004867,response to wounding; serine-type endopeptidase inhibitor activity,PF00280;,,,,,,,,,ICI1_CANLI,Canavalia lineata (Beach bean) (Dolichos lineatus),response to wounding [GO:0009611] comp123073_c0_seq2,412,38.835,0.53025509,2,25,,6.00E-09,P16064,Subtilisin inhibitor 1 (ASI-I) (Subtilisin inhibitor I) [Cleaved into: Subtilisin inhibitor 2 (ASI-II) (Subtilisin inhibitor II)],Subtilisin inhibitor 1 (ASI-I) (Subtilisin inhibitor I) [Cleaved into: Subtilisin inhibitor 2 (ASI-II) (Subtilisin inhibitor II)],GO:0009611; GO:0004867,response to wounding; serine-type endopeptidase inhibitor activity,PF00280;,,,,,,,,,ICI1_PHAAN,Phaseolus angularis (Azuki bean) (Vigna angularis),response to wounding [GO:0009611] comp123086_c0_seq2,619,43.2956,0.45383001,4,0,,2.00E-28,Q9UBC2,Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R),Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R),GO:0005509; GO:0005905; GO:0006897; GO:0007173; GO:0042059; GO:0005634; GO:0005886,calcium ion binding; coated pit; endocytosis; epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; nucleus; plasma membrane,PF12763;,,,,,,,,,EP15R_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp123086_c1_seq1,1128,48.3156,0.24478974,49,64,,6.00E-115,Q9UBC2,Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R),Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R),GO:0005509; GO:0005905; GO:0006897; GO:0007173; GO:0042059; GO:0005634; GO:0005886,calcium ion binding; coated pit; endocytosis; epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; nucleus; plasma membrane,PF12763;,1.00E-29,CHOYP_EP15R.1.1,1.00E-20,ruditapes_c22994,,,,,EP15R_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp123091_c1_seq1,1284,43.3801,0.58599384,35,33,,2.00E-79,F1NTD6,Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0006307; GO:0008283; GO:0005737; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA dealkylation involved in DNA repair; cell proliferation; cytoplasm; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00270;PF00271;PF02889;,8.00E-32,CHOYP_ASCC3.1.1,,,,,,,ASCC3_CHICK,Gallus gallus (Chicken),"cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123092_c0_seq1,1245,37.992,0.4248594,18,123,,4.00E-84,Q8IUS5,Epoxide hydrolase 4 (EC 3.3.-.-) (Abhydrolase domain-containing protein 7) (Epoxide hydrolase-related protein),Epoxide hydrolase 4 (EC 3.3.-.-) (Abhydrolase domain-containing protein 7) (Epoxide hydrolase-related protein),GO:0016787; GO:0016021; GO:0008152,hydrolase activity; integral to membrane; metabolic process,PF00561;,3.00E-31,CHOYP_LOC100376692.1.1,,,,,,,EPHX4_HUMAN,Homo sapiens (Human), comp123092_c0_seq2,396,45.9596,0.5383417,0,10,,5.00E-13,Q6Q3H0,Haloalkane dehalogenase (EC 3.8.1.5),Haloalkane dehalogenase (EC 3.8.1.5),GO:0019260; GO:0018786; GO:0009636,"1,2-dichloroethane catabolic process; haloalkane dehalogenase activity; response to toxic substance",PF00561;,,,,,,,,,DHLA_XANFL,Xanthobacter flavus,"1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]" comp123093_c0_seq1,1344,41.8155,0.63024819,2775,107,,4.00E-80,Q8C552,Protein FAM78A,Protein FAM78A,,,,2.00E-103,CHOYP_LOC100668624.1.1,,,,,,,FA78A_MOUSE,Mus musculus (Mouse), comp123096_c1_seq1,580,43.2759,0.52081087,43,11,,6.00E-37,Q9BXW9,Fanconi anemia group D2 protein (Protein FACD2),Fanconi anemia group D2 protein (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0005654; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; nucleoplasm; response to gamma radiation; synapsis,PF14631;,,,,,,,,,FACD2_HUMAN,Homo sapiens (Human),gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp123100_c0_seq1,223,27.3543,0.97605449,25,46,,,,,,,,,,,5.00E-16,ruditapes_c27272,,,,,,, comp123102_c1_seq1,676,44.8225,0.56048053,30,50,,2.00E-14,Q8NDA2,Hemicentin-2,Hemicentin-2,GO:0005509; GO:0005578; GO:0050896,calcium ion binding; proteinaceous extracellular matrix; response to stimulus,PF12662;PF07645;PF07474;PF07679;,3.00E-14,CHOYP_PTPRF.5.6,,,,,,,HMCN2_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896] comp123102_c2_seq1,1410,47.5887,0.438744,0,0,,2.00E-32,O88488,Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1) (rPTP-GMC1) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48),Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1) (rPTP-GMC1) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48),GO:0016021; GO:0035335; GO:0005886; GO:0004725; GO:0045598,integral to membrane; peptidyl-tyrosine dephosphorylation; plasma membrane; protein tyrosine phosphatase activity; regulation of fat cell differentiation,PF00041;PF00102;,,,,,,,,,PTPRQ_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of fat cell differentiation [GO:0045598] comp123102_c2_seq2,1603,46.9744,0.4753198,6,7,,6.00E-109,P23468,Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48),GO:0050839; GO:0007157; GO:0005887; GO:0030182; GO:0050775; GO:0097105; GO:0005102; GO:0005001; GO:0007185,cell adhesion molecule binding; heterophilic cell-cell adhesion; integral to plasma membrane; neuron differentiation; positive regulation of dendrite morphogenesis; presynaptic membrane assembly; receptor binding; transmembrane receptor protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase signaling pathway,PF00041;PF07679;PF00102;,,,,,,,,,PTPRD_HUMAN,Homo sapiens (Human),chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] comp123102_c2_seq3,1478,47.1583,0.47497551,3,0,,2.00E-30,P43146,Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC),Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC),GO:0033564; GO:0006915; GO:0030424; GO:0007411; GO:0005829; GO:0033563; GO:0032584; GO:0016021; GO:0045121; GO:0048671; GO:2000171; GO:0005042; GO:0001764; GO:0005886; GO:0070374; GO:0043065; GO:0010976; GO:0001975; GO:0021965; GO:0003713; GO:0004888,anterior/posterior axon guidance; apoptotic process; axon; axon guidance; cytosol; dorsal/ventral axon guidance; growth cone membrane; integral to membrane; membrane raft; negative regulation of collateral sprouting; negative regulation of dendrite development; netrin receptor activity; neuron migration; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of apoptotic process; positive regulation of neuron projection development; response to amphetamine; spinal cord ventral commissure morphogenesis; transcription coactivator activity; transmembrane signaling receptor activity,PF00041;PF07679;PF06583;,,,,,,,,,DCC_HUMAN,Homo sapiens (Human),anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965] comp123103_c1_seq1,948,43.1435,0.39640813,49,36,,1.00E-36,A9JRI0,HEAT repeat-containing protein 6,HEAT repeat-containing protein 6,,,PF13251;,3.00E-35,CHOYP_HEAT6.1.1,,,,,,,HEAT6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp123103_c2_seq1,707,43.14,0.33531454,31,4,,1.00E-31,A1EC95,HEAT repeat-containing protein 6,HEAT repeat-containing protein 6,,,PF13251;,,,,,,,,,HEAT6_RAT,Rattus norvegicus (Rat), comp123104_c1_seq1,351,27.0655,0.31372804,4,19,,,,,,,,,,,5.00E-12,ruditapes_c30227,,,,,,, comp123109_c1_seq1,863,48.4357,0.53416448,15,4,,1.00E-50,Q9VT28,Protein furry,Protein furry,GO:0048800; GO:0045177; GO:0005938; GO:0008407; GO:0070593; GO:0035317; GO:0048601; GO:0045860; GO:0045893; GO:0048814; GO:0042052; GO:0006351,"antennal morphogenesis; apical part of cell; cell cortex; chaeta morphogenesis; dendrite self-avoidance; imaginal disc-derived wing hair organization; oocyte morphogenesis; positive regulation of protein kinase activity; positive regulation of transcription, DNA-dependent; regulation of dendrite morphogenesis; rhabdomere development; transcription, DNA-dependent",PF14225;PF14228;PF14222;,1.00E-91,CHOYP_LOC657755.1.1,,,,,,,FRY_DROME,Drosophila melanogaster (Fruit fly),"actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]" comp123115_c0_seq3,450,43.5556,0.51790631,16,10,,2.00E-48,Q9BQ24,Zinc finger FYVE domain-containing protein 21 (ZF21),Zinc finger FYVE domain-containing protein 21 (ZF21),GO:0016023; GO:0005768; GO:0005925; GO:0046872,cytoplasmic membrane-bounded vesicle; endosome; focal adhesion; metal ion binding,PF01363;PF16696;,,,,,,,,,ZFY21_HUMAN,Homo sapiens (Human), comp123124_c0_seq1,1390,36.9784,0.25899562,1907,7731,,4.00E-144,P21670,Proteasome subunit alpha type-4 (EC 3.4.25.1) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L),Proteasome subunit alpha type-4 (EC 3.4.25.1) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L),GO:0000932; GO:0005634; GO:0005839; GO:0019773; GO:0004298; GO:0006511,"cytoplasmic mRNA processing body; nucleus; proteasome core complex; proteasome core complex, alpha-subunit complex; threonine-type endopeptidase activity; ubiquitin-dependent protein catabolic process",PF00227;PF10584;,1.00E-143,CHOYP_PSA4.1.1,9.00E-99,ruditapes_c5293,,,,,PSA4_RAT,Rattus norvegicus (Rat),ubiquitin-dependent protein catabolic process [GO:0006511] comp123130_c0_seq1,1007,47.8649,0.26048781,2,0,,6.00E-46,Q291E4,Protein virilizer,Protein virilizer,GO:0000375; GO:0006397; GO:0005634; GO:0007539; GO:0000381,"RNA splicing, via transesterification reactions; mRNA processing; nucleus; primary sex determination, soma; regulation of alternative mRNA splicing, via spliceosome",PF15912;,,,,,,,,,VIR_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),"mRNA processing [GO:0006397]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing, via transesterification reactions [GO:0000375]" comp123130_c0_seq3,473,43.9746,0.39474591,0,0,,2.00E-48,Q291E4,Protein virilizer,Protein virilizer,GO:0000375; GO:0006397; GO:0005634; GO:0007539; GO:0000381,"RNA splicing, via transesterification reactions; mRNA processing; nucleus; primary sex determination, soma; regulation of alternative mRNA splicing, via spliceosome",PF15912;,,,,,,,,,VIR_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),"mRNA processing [GO:0006397]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing, via transesterification reactions [GO:0000375]" comp123130_c0_seq6,1040,47.7885,0.25298944,13,0,,5.00E-29,Q69YN4,Protein virilizer homolog,Protein virilizer homolog,GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF15912;,4.00E-40,CHOYP_VIR.1.1,,,,,,,VIR_HUMAN,Homo sapiens (Human),mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp123133_c0_seq1,827,40.9915,0.9272779,0,9,,4.00E-22,P54761,Ephrin type-B receptor 4 (EC 2.7.10.1) (Developmental kinase 2) (mDK-2) (Hepatoma transmembrane kinase) (Tyrosine kinase MYK-1),Ephrin type-B receptor 4 (EC 2.7.10.1) (Developmental kinase 2) (mDK-2) (Hepatoma transmembrane kinase) (Tyrosine kinase MYK-1),GO:0005524; GO:0007155; GO:0002042; GO:0005003; GO:0003007; GO:0005887; GO:0046777,ATP binding; cell adhesion; cell migration involved in sprouting angiogenesis; ephrin receptor activity; heart morphogenesis; integral to plasma membrane; protein autophosphorylation,PF14575;PF01404;PF07699;PF00041;PF07714;PF00536;,,,,,,,,,EPHB4_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of T cell costimulation [GO:2000525]; protein autophosphorylation [GO:0046777]; venous blood vessel morphogenesis [GO:0048845] comp123133_c0_seq2,826,42.1308,0.88063754,5,4,,1.00E-39,P09759,Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (Tyrosine-protein kinase receptor EPH-2),Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (Tyrosine-protein kinase receptor EPH-2),GO:0005524; GO:0001525; GO:0030424; GO:0008046; GO:0048593; GO:0060326; GO:0031589; GO:0021952; GO:0030425; GO:0060997; GO:0050965; GO:0031901; GO:0030010; GO:0005887; GO:0045121; GO:0061351; GO:0021631; GO:0051965; GO:0046777; GO:0070372; GO:0046328; GO:0031290; GO:0005005,ATP binding; angiogenesis; axon; axon guidance receptor activity; camera-type eye morphogenesis; cell chemotaxis; cell-substrate adhesion; central nervous system projection neuron axonogenesis; dendrite; dendritic spine morphogenesis; detection of temperature stimulus involved in sensory perception of pain; early endosome membrane; establishment of cell polarity; integral to plasma membrane; membrane raft; neural precursor cell proliferation; optic nerve morphogenesis; positive regulation of synapse assembly; protein autophosphorylation; regulation of ERK1 and ERK2 cascade; regulation of JNK cascade; retinal ganglion cell axon guidance; transmembrane-ephrin receptor activity,PF14575;PF01404;PF00041;PF07714;PF00536;,,,,,,,,,EPHB1_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; immunological synapse formation [GO:0001771]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290] comp123135_c0_seq1,867,38.639,0.49695908,612,1774,,2.00E-51,Q64471,Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),GO:0005829; GO:0006749; GO:0004602; GO:0004364; GO:0005634; GO:0042493; GO:0014070,cytosol; glutathione metabolic process; glutathione peroxidase activity; glutathione transferase activity; nucleus; response to drug; response to organic cyclic compound,PF00043;PF02798;,,,,,,,,,GSTT1_MOUSE,Mus musculus (Mouse),dichloromethane metabolic process [GO:0018900]; DNA modification [GO:0006304]; glutathione metabolic process [GO:0006749]; response to drug [GO:0042493]; response to salicylic acid [GO:0009751]; response to selenium ion [GO:0010269]; response to vitamin E [GO:0033197] comp123141_c0_seq2,1100,44.1818,0.79094893,36,40,,2.00E-130,Q6UE39,Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13),Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13),GO:0000139; GO:0016021; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,9.00E-125,CHOYP_GLT13.2.2,,,,,,,GLT13_RAT,Rattus norvegicus (Rat),protein O-linked glycosylation [GO:0006493] comp123141_c0_seq3,373,42.0912,0.6426163,0,0,,2.00E-08,Q8IUC8,Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13),Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13),GO:0000139; GO:0016266; GO:0016021; GO:0004653; GO:0043687,Golgi membrane; O-glycan processing; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; post-translational protein modification,PF00535;PF00652;,,,,,,,,,GLT13_HUMAN,Homo sapiens (Human),O-glycan processing [GO:0016266] comp123142_c0_seq2,511,35.225,0.82673276,30,7,,,,,,,,,,,1.00E-10,ruditapes_c26218,,,,,,, comp123149_c0_seq1,820,42.439,0.21815557,12,49,,4.00E-84,Q499N4,"4-hydroxybenzoate polyprenyltransferase, mitochondrial (EC 2.5.1.39) (Para-hydroxybenzoate--polyprenyltransferase) (PHB:polyprenyltransferase)","4-hydroxybenzoate polyprenyltransferase, mitochondrial (4-HB polyprenyltransferase) (EC 2.5.1.39) (Para-hydroxybenzoate--polyprenyltransferase) (PHB:PPT) (PHB:polyprenyltransferase)",GO:0002083; GO:0047293; GO:0016021; GO:0008299; GO:0031966; GO:0006744,4-hydroxybenzoate decaprenyltransferase activity; 4-hydroxybenzoate nonaprenyltransferase activity; integral to membrane; isoprenoid biosynthetic process; mitochondrial membrane; ubiquinone biosynthetic process,PF01040;,7.00E-68,CHOYP_COQ2.2.3,,,,,,,COQ2_RAT,Rattus norvegicus (Rat),isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744] comp123149_c1_seq1,390,47.6923,0.27152956,7,40,,,,,,,,,4.00E-42,CHOYP_COQ2.3.3,,,,,,,,, comp123160_c0_seq1,461,46.2039,1.38739392,0,0,,,,,,,,,,,3.00E-16,ruditapes2_c2711,,,,,,, comp123160_c0_seq6,225,44.8889,1.153084,0,16,,,,,,,,,,,3.00E-13,ruditapes_c29520,,,,,,, comp123164_c0_seq2,679,49.0427,0.61336545,30,18,,5.00E-16,Q8K3E5,Jouberin (Abelson helper integration site 1 protein) (AHI-1),Jouberin (Abelson helper integration site 1 protein) (AHI-1),GO:0070121; GO:0036038; GO:0005912; GO:0005911; GO:0005814; GO:0042384; GO:0035844; GO:0001947; GO:0030902; GO:0070986; GO:0005932; GO:0001738; GO:0043066; GO:0071599; GO:0035845; GO:0001750; GO:0030862; GO:0002092; GO:0045944; GO:0039023; GO:0039008; GO:0033365; GO:0050795; GO:0010842; GO:0065001; GO:0007169; GO:0006903,Kupffer's vesicle development; TCTN-B9D complex; adherens junction; cell-cell junction; centriole; cilium assembly; cloaca development; heart looping; hindbrain development; left/right axis specification; microtubule basal body; morphogenesis of a polarized epithelium; negative regulation of apoptotic process; otic vesicle development; photoreceptor cell outer segment organization; photoreceptor outer segment; positive regulation of polarized epithelial cell differentiation; positive regulation of receptor internalization; positive regulation of transcription from RNA polymerase II promoter; pronephric duct morphogenesis; pronephric nephron tubule morphogenesis; protein localization to organelle; regulation of behavior; retina layer formation; specification of axis polarity; transmembrane receptor protein tyrosine kinase signaling pathway; vesicle targeting,PF00018;PF00400;,5.00E-18,CHOYP_LOC100892609.1.1,,,,,,,AHI1_MOUSE,Mus musculus (Mouse),cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cloaca development [GO:0035844]; eye photoreceptor cell development [GO:0042462]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of neuron projection development [GO:0010976]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; protein localization to organelle [GO:0033365]; regulation of behavior [GO:0050795]; regulation of protein secretion [GO:0050708]; retina development in camera-type eye [GO:0060041]; retina layer formation [GO:0010842]; retinal cone cell development [GO:0046549]; retinal rod cell development [GO:0046548]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192]; vesicle targeting [GO:0006903] comp123172_c0_seq1,423,39.4799,0.61988651,0,0,,3.00E-23,Q2LE78,BTB/POZ domain-containing protein 6,BTB/POZ domain-containing protein 6,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD6_XENLA,Xenopus laevis (African clawed frog), comp123172_c0_seq2,457,39.8249,0.62313224,0,0,,1.00E-11,A0JMG1,Speckle-type POZ protein-like B (HIB homolog 3),Speckle-type POZ protein-like B (HIB homolog 3),GO:0031463; GO:0031397; GO:0005634; GO:0043161; GO:0016567,Cul3-RING ubiquitin ligase complex; negative regulation of protein ubiquitination; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination,PF00651;PF00917;,,,,,,,,,SPOLB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of protein ubiquitination [GO:0031397]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] comp123175_c0_seq1,1155,41.4719,0.88957358,0,9,,2.00E-62,Q23490,Peroxidase mlt-7 (EC 1.11.1.7) (Molting defective protein 7) (MoLT-7) [Cleaved into: Peroxidase mlt-7 light chain; Peroxidase mlt-7 heavy chain],Peroxidase mlt-7 (EC 1.11.1.7) (Molting defective protein 7) (MoLT-7) [Cleaved into: Peroxidase mlt-7 light chain; Peroxidase mlt-7 heavy chain],GO:0042338; GO:0020037; GO:0046872; GO:0002119; GO:0018149; GO:0004601; GO:0040032; GO:0006979,cuticle development involved in collagen and cuticulin-based cuticle molting cycle; heme binding; metal ion binding; nematode larval development; peptide cross-linking; peroxidase activity; post-embryonic body morphogenesis; response to oxidative stress,PF03098;PF01549;,,,,,,,,,MLT7_CAEEL,Caenorhabditis elegans,cuticle development involved in collagen and cuticulin-based cuticle molting cycle [GO:0042338]; nematode larval development [GO:0002119]; peptide cross-linking [GO:0018149]; post-embryonic body morphogenesis [GO:0040032]; response to oxidative stress [GO:0006979] comp123175_c0_seq2,1644,40.8759,0.92061115,0,162,,2.00E-79,P49290,Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain],Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain],GO:0002215; GO:0072677; GO:0020037; GO:0042744; GO:0046872; GO:0032693; GO:0032714; GO:0004601; GO:0032753,defense response to nematode; eosinophil migration; heme binding; hydrogen peroxide catabolic process; metal ion binding; negative regulation of interleukin-10 production; negative regulation of interleukin-5 production; peroxidase activity; positive regulation of interleukin-4 production,PF03098;,,,,,,,,,PERE_MOUSE,Mus musculus (Mouse),defense response to nematode [GO:0002215]; eosinophil migration [GO:0072677]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-5 production [GO:0032714]; positive regulation of interleukin-4 production [GO:0032753]; response to oxidative stress [GO:0006979] comp123176_c0_seq1,851,41.1281,0.90454987,10,82,,6.00E-81,P18293,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0005525; GO:0042417; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0048662; GO:0017046; GO:0005886; GO:0030828; GO:0004672; GO:0007168; GO:0050880,ATP binding; GTP binding; dopamine metabolic process; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of smooth muscle cell proliferation; peptide hormone binding; plasma membrane; positive regulation of cGMP biosynthetic process; protein kinase activity; receptor guanylyl cyclase signaling pathway; regulation of blood vessel size,PF01094;PF00211;PF07714;,4.00E-65,CHOYP_GCY.4.4,4.00E-12,ruditapes_c24373,,,,,ANPRA_MOUSE,Mus musculus (Mouse),cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880] comp123178_c0_seq1,1256,39.8885,0.38247094,73,433,,5.00E-78,Q9H0E2,Toll-interacting protein,Toll-interacting protein,GO:0007267; GO:0005829; GO:0006954; GO:0045087; GO:0045323; GO:0045092; GO:0035556; GO:0045321; GO:0016604; GO:0048471; GO:0016310; GO:0033235; GO:0004871,cell-cell signaling; cytosol; inflammatory response; innate immune response; interleukin-1 receptor complex; interleukin-18 receptor complex; intracellular signal transduction; leukocyte activation; nuclear body; perinuclear region of cytoplasm; phosphorylation; positive regulation of protein sumoylation; signal transducer activity,PF00168;PF02845;,3.00E-36,CHOYP_TOLIP.1.1,,,,,,,TOLIP_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; epithelial cell differentiation [GO:0030855]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte activation [GO:0045321]; phosphorylation [GO:0016310]; positive regulation of protein sumoylation [GO:0033235]; protein localization to endosome [GO:0036010]; signal transduction [GO:0007165] comp123180_c0_seq1,824,40.0485,1.25912187,37,5919,female>male,2.00E-20,O96790,Serine protease inhibitor dipetalogastin (Dipetalin) (Fragment),Serine protease inhibitor dipetalogastin (Dipetalin) (Fragment),GO:0005576; GO:0050819; GO:0004867,extracellular region; negative regulation of coagulation; serine-type endopeptidase inhibitor activity,PF00050;PF07648;,,,,,,,,,DPGN_DIPMA,Dipetalogaster maximus (Blood-sucking bug),negative regulation of coagulation [GO:0050819] comp123187_c0_seq1,1543,36.0337,1.02021187,1713,7350,,4.00E-47,P12981,Transcription factor AP-1 (Proto-oncogene c-Jun),Transcription factor AP-1 (Proto-oncogene c-Jun),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00170;PF03957;,6.00E-34,CHOYP_LOC101077059.1.1,5.00E-90,ruditapes_c15865,,,,,JUN_COTJA,Coturnix coturnix japonica (Japanese quail) (Coturnix japonica),"Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]" comp123190_c0_seq1,1001,43.7562,0.71630189,29,320,,2.00E-36,P79171,Aminopeptidase N (AP-N) (fAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (fAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0019048; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; modulation by virus of host morphology or physiology; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_FELCA,Felis catus (Cat) (Felis silvestris catus),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp123196_c0_seq1,1489,43.452,0.70714636,2,0,,4.00E-07,Q9VUX2,E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib),E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib),GO:0007219; GO:0045179; GO:0005829; GO:0006897; GO:0046331; GO:0045747; GO:0008104; GO:0007423; GO:0004842; GO:0008270,Notch signaling pathway; apical cortex; cytosol; endocytosis; lateral inhibition; positive regulation of Notch signaling pathway; protein localization; sensory organ development; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB_DROME,Drosophila melanogaster (Fruit fly),compound eye development [GO:0048749]; endocytosis [GO:0006897]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of Notch signaling pathway [GO:0008593]; sensory organ development [GO:0007423] comp123224_c0_seq1,566,37.6325,0.70062002,1195,2343,,4.00E-24,Q3SZA2,UPF0562 protein C7orf55 homolog,UPF0562 protein C7orf55 homolog,,,,,,,,,,,,CG055_BOVIN,Bos taurus (Bovine), comp123227_c0_seq1,3197,44.8858,0.5156021,240,239,,3.00E-90,Q5R5U3,Zinc finger protein 271,Zinc finger protein 271,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN271_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123233_c0_seq1,341,46.9208,1.12289896,16,16,,2.00E-15,Q96MB7,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_HUMAN,Homo sapiens (Human), comp123236_c0_seq1,702,39.7436,0.90649039,13,763,,,,,,,,,,,6.00E-28,ruditapes2_c3202,,,,,,, comp123243_c0_seq1,561,40.9982,0.81486828,9,7,,6.00E-60,Q86VP3,Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein),Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein),GO:0006915; GO:0005783; GO:0005788; GO:0005739; GO:0019048; GO:0072661,apoptotic process; endoplasmic reticulum; endoplasmic reticulum lumen; mitochondrion; modulation by virus of host morphology or physiology; protein targeting to plasma membrane,PF10254;,2.00E-27,CHOYP_LOC100373559.1.1,,,,,,,PACS2_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; protein localization to pre-autophagosomal structure [GO:0034497]; protein targeting to plasma membrane [GO:0072661]; viral process [GO:0016032] comp12325_c0_seq1,313,45.3674,0.38130322,4,0,,8.00E-09,A4IFW2,Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48),GO:0007155; GO:0008201; GO:0016021; GO:0035335; GO:0004725; GO:0097374,cell adhesion; heparin binding; integral to membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; sensory neuron axon guidance,PF00041;PF07679;PF00102;,,,,,,,,,PTPRF_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; sensory neuron axon guidance [GO:0097374] comp123261_c0_seq2,543,38.674,0.49347047,22,30,,6.00E-08,O42154,Glucose-6-phosphatase (G-6-Pase) (G6Pase) (EC 3.1.3.9) (Fragment),Glucose-6-phosphatase (G-6-Pase) (G6Pase) (EC 3.1.3.9) (Fragment),GO:0005789; GO:0006094; GO:0004346; GO:0016021,endoplasmic reticulum membrane; gluconeogenesis; glucose-6-phosphatase activity; integral to membrane,PF01569;,,,,,,,,,G6PC_HAPXE,Haplochromis xenognathus (Lake Victoria cichlid) (Ptyochromis xenognathus),gluconeogenesis [GO:0006094] comp123261_c1_seq1,571,42.2067,0.4350124,13,58,,3.00E-34,A1A5Z0,Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9),Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9),GO:0005789; GO:0006094; GO:0004346; GO:0016021,endoplasmic reticulum membrane; gluconeogenesis; glucose-6-phosphatase activity; integral to membrane,PF01569;,,,,,,,,,G6PC3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156] comp123271_c0_seq1,807,44.2379,0.25368956,34,46,,6.00E-107,Q32PW3,Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),GO:0008237; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"metallopeptidase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01433;,2.00E-132,CHOYP_LOC100706922.1.1,,,,,,,TAF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp123276_c0_seq1,570,45.0877,0.56922294,26,70,,2.00E-39,Q9UHG3,Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase),Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase),GO:0008555; GO:0005764; GO:0005886; GO:0030327; GO:0030328; GO:0030329; GO:0001735; GO:0034361,chloride-transporting ATPase activity; lysosome; plasma membrane; prenylated protein catabolic process; prenylcysteine catabolic process; prenylcysteine metabolic process; prenylcysteine oxidase activity; very-low-density lipoprotein particle,PF07156;,,,,,,,,,PCYOX_HUMAN,Homo sapiens (Human),prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328]; prenylcysteine metabolic process [GO:0030329] comp123278_c0_seq1,807,42.2553,0.6446073,8,137,,8.00E-74,Q9Y4D1,Disheveled-associated activator of morphogenesis 1,Disheveled-associated activator of morphogenesis 1,GO:0030036; GO:0005737; GO:0005886; GO:0001725,actin cytoskeleton organization; cytoplasm; plasma membrane; stress fiber,PF06367;PF06371;PF02181;,9.00E-35,CHOYP_LOC658864.1.1,,,,,,,DAAM1_HUMAN,Homo sapiens (Human),"actin cytoskeleton organization [GO:0030036]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp123278_c1_seq1,656,48.0183,0.50641091,2,77,,1.00E-07,Q9LVN1,Formin-like protein 13 (AtFH13),Formin-like protein 13 (AtFH13),GO:0005884; GO:0045010; GO:0004721,actin filament; actin nucleation; phosphoprotein phosphatase activity,PF02181;PF10409;,,,,,,,,,FH13_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp123283_c0_seq2,556,37.4101,0.1656593,21,11,,2.00E-08,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp123284_c0_seq1,838,45.7041,0.45794509,0,0,,9.00E-46,Q96PX1,RING finger protein 157,RING finger protein 157,GO:0008270,zinc ion binding,,6.00E-63,CHOYP_LOC659409.1.1,,,,,,,RN157_HUMAN,Homo sapiens (Human), comp123284_c0_seq2,1378,45.283,0.45378659,0,0,,1.00E-21,Q84ME1,Probable E3 ubiquitin-protein ligase LUL3 (EC 6.3.2.-) (Protein LOG2-LIKE UBIQUITIN LIGASE 3) (RING finger protein 398),Probable E3 ubiquitin-protein ligase LUL3 (EC 6.3.2.-) (Protein LOG2-LIKE UBIQUITIN LIGASE 3) (RING finger protein 398),GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,LUL3_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp123286_c0_seq1,1213,43.9406,0.35167024,41,40,,8.00E-56,P20072,Annexin A7 (Annexin VII) (Annexin-7) (Synexin),Annexin A7 (Annexin VII) (Annexin-7) (Synexin),GO:0005509; GO:0005544; GO:0008283; GO:0006874; GO:0009992; GO:0042584; GO:0005829; GO:0005789; GO:0007599; GO:0005635; GO:0005886; GO:0008360; GO:0009651; GO:0035176,calcium ion binding; calcium-dependent phospholipid binding; cell proliferation; cellular calcium ion homeostasis; cellular water homeostasis; chromaffin granule membrane; cytosol; endoplasmic reticulum membrane; hemostasis; nuclear envelope; plasma membrane; regulation of cell shape; response to salt stress; social behavior,PF00191;,8.00E-158,CHOYP_ANXA6.1.2,,,,,,,ANXA7_BOVIN,Bos taurus (Bovine),autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176] comp123292_c0_seq1,1199,42.5354,0.35065619,29,38,,5.00E-130,Q62829,Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (p21-activated kinase 3) (PAK-3) (p65-PAK),Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (p21-activated kinase 3) (PAK-3) (p65-PAK),GO:0005524; GO:0051020; GO:0004708; GO:0007409; GO:0005737; GO:0016358; GO:0046872; GO:0004674; GO:0030833,ATP binding; GTPase binding; MAP kinase kinase activity; axonogenesis; cytoplasm; dendrite development; metal ion binding; protein serine/threonine kinase activity; regulation of actin filament polymerization,PF00786;PF00069;,6.00E-172,CHOYP_LOC100160077.1.1,8.00E-23,ruditapes_c18564,,,,,PAK3_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; cellular response to organic cyclic compound [GO:0071407]; dendrite development [GO:0016358]; dendritic spine development [GO:0060996]; intracellular signal transduction [GO:0035556]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of neuron apoptotic process [GO:0043525]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of neuron projection development [GO:0010975] comp123292_c0_seq2,535,41.8692,0.31904873,2,0,,3.00E-54,Q4P5N0,Serine/threonine-protein kinase SMU1 (EC 2.7.11.1),Serine/threonine-protein kinase SMU1 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0005634; GO:0004674; GO:0019236,ATP binding; cytoplasm; nucleus; protein serine/threonine kinase activity; response to pheromone,PF00786;PF00069;,1.00E-126,CHOYP_LOC100160077.1.1,,,,,,,STE20_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),mitotic cell cycle [GO:0000278]; response to pheromone [GO:0019236] comp123294_c2_seq3,593,43.0017,0.25787719,0,4,,,,,,,,,2.00E-15,CHOYP_LOC100881043.1.1,,,,,,,,, comp123302_c1_seq1,1525,43.4098,0.7198316,25,76,,0,A1A5H8,Tyrosine-protein kinase yes (EC 2.7.10.2) (p61-Yes),Tyrosine-protein kinase yes (EC 2.7.10.2) (p61-Yes),GO:0005524; GO:0060027; GO:0005829; GO:0005815; GO:0004715; GO:0005886; GO:0046777; GO:0004713; GO:0045859,ATP binding; convergent extension involved in gastrulation; cytosol; microtubule organizing center; non-membrane spanning protein tyrosine kinase activity; plasma membrane; protein autophosphorylation; protein tyrosine kinase activity; regulation of protein kinase activity,PF07714;PF00017;PF00018;,2.00E-121,CHOYP_SRC.2.2,9.00E-49,ruditapes_c25919,,,,,YES_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell differentiation [GO:0030154]; convergent extension involved in gastrulation [GO:0060027]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein autophosphorylation [GO:0046777]; regulation of cell proliferation [GO:0042127]; regulation of protein kinase activity [GO:0045859]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp123302_c1_seq2,432,40.0463,1.04337908,0,10,,6.00E-62,P42689,Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment),Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment),GO:0005524; GO:0005737; GO:0004715; GO:0018108,ATP binding; cytoplasm; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF07714;,3.00E-18,CHOYP_SRC1.1.1,,,,,,,SRK3_SPOLA,Spongilla lacustris (Freshwater sponge), comp123302_c1_seq3,814,42.8747,0.48511978,0,0,,3.00E-55,P08103,Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK),Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK),GO:0005524; GO:0005794; GO:0005901; GO:0042995; GO:0005856; GO:0005829; GO:0050830; GO:0006887; GO:0031234; GO:0005925; GO:0006954; GO:0045087; GO:0005764; GO:0004715; GO:0005634; GO:0006909; GO:2000251; GO:0008284; GO:0046777; GO:0004713; GO:0008360; GO:0050764; GO:0071801; GO:0030133,ATP binding; Golgi apparatus; caveola; cell projection; cytoskeleton; cytosol; defense response to Gram-positive bacterium; exocytosis; extrinsic to internal side of plasma membrane; focal adhesion; inflammatory response; innate immune response; lysosome; non-membrane spanning protein tyrosine kinase activity; nucleus; phagocytosis; positive regulation of actin cytoskeleton reorganization; positive regulation of cell proliferation; protein autophosphorylation; protein tyrosine kinase activity; regulation of cell shape; regulation of phagocytosis; regulation of podosome assembly; transport vesicle,PF07714;PF00017;PF00018;,,,9.00E-33,ruditapes_c17152,,,,,HCK_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cytoskeleton organization [GO:0007010]; defense response to Gram-positive bacterium [GO:0050830]; exocytosis [GO:0006887]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp123302_c1_seq4,202,46.0396,1.03382163,4,9,,,,,,,,,5.00E-11,CHOYP_LOAG_10645.1.1,,,,,,,,, comp123306_c0_seq1,1083,38.8735,0.28053854,13,4,,4.00E-06,P17020,Zinc finger protein 16 (Zinc finger protein KOX9),Zinc finger protein 16 (Zinc finger protein KOX9),GO:0003677; GO:0007049; GO:0051301; GO:0072707; GO:0046872; GO:0043066; GO:0005634; GO:1901989; GO:0051781; GO:0008284; GO:0045648; GO:0033674; GO:0045654; GO:0006355; GO:0006351,"DNA binding; cell cycle; cell division; cellular response to sodium dodecyl sulfate; metal ion binding; negative regulation of apoptotic process; nucleus; positive regulation of cell cycle phase transition; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of erythrocyte differentiation; positive regulation of kinase activity; positive regulation of megakaryocyte differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZNF16_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123306_c0_seq2,849,40.8716,0.26397552,0,0,,4.00E-08,Q2VWH6,Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like),Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like),GO:0000978; GO:0007411; GO:0007413; GO:0021853; GO:0016358; GO:0021542; GO:0021797; GO:0007626; GO:0046872; GO:0008285; GO:0000122; GO:0005634; GO:0045666; GO:0045893; GO:0006351,"RNA polymerase II core promoter proximal region sequence-specific DNA binding; axon guidance; axonal fasciculation; cerebral cortex GABAergic interneuron migration; dendrite development; dentate gyrus development; forebrain anterior/posterior pattern specification; locomotory behavior; metal ion binding; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,FEZF2_BOVIN,Bos taurus (Bovine),"axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cerebral cortex GABAergic interneuron migration [GO:0021853]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; dendrite development [GO:0016358]; dentate gyrus development [GO:0021542]; forebrain anterior/posterior pattern specification [GO:0021797]; locomotory behavior [GO:0007626]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron fate determination [GO:0048664]; positive regulation of neuron differentiation [GO:0045666]; regulation of axon guidance [GO:1902667]" comp123309_c0_seq2,1431,48.7072,0.6487113,0,0,,9.00E-62,P84023,Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3),Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3),GO:0071141; GO:0042110; GO:0006919; GO:0007050; GO:0045216; GO:0031490; GO:0000987; GO:0005737; GO:0019049; GO:0097191; GO:0006955; GO:0030308; GO:0050728; GO:0045930; GO:0033689; GO:0042177; GO:0001933; GO:0061045; GO:0038092; GO:0005637; GO:0005634; GO:0001649; GO:0090263; GO:0035413; GO:0032332; GO:0010718; GO:1901313; GO:0042993; GO:0045893; GO:0000988; GO:0050821; GO:0043235; GO:0050776; GO:0032909; GO:0001666; GO:0003700; GO:0005667; GO:0006351; GO:0007179; GO:0030618; GO:0006810; GO:0001657; GO:0008270,"SMAD protein complex; T cell activation; activation of cysteine-type endopeptidase activity involved in apoptotic process; cell cycle arrest; cell-cell junction organization; chromatin DNA binding; core promoter proximal region sequence-specific DNA binding; cytoplasm; evasion or tolerance of host defenses by virus; extrinsic apoptotic signaling pathway; immune response; negative regulation of cell growth; negative regulation of inflammatory response; negative regulation of mitotic cell cycle; negative regulation of osteoblast proliferation; negative regulation of protein catabolic process; negative regulation of protein phosphorylation; negative regulation of wound healing; nodal signaling pathway; nuclear inner membrane; nucleus; osteoblast differentiation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of catenin import into nucleus; positive regulation of chondrocyte differentiation; positive regulation of epithelial to mesenchymal transition; positive regulation of gene expression involved in extracellular matrix organization; positive regulation of transcription factor import into nucleus; positive regulation of transcription, DNA-dependent; protein binding transcription factor activity; protein stabilization; receptor complex; regulation of immune response; regulation of transforming growth factor beta2 production; response to hypoxia; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; transport; ureteric bud development; zinc ion binding",PF03165;PF03166;,,,,,,,,,SMAD3_CHICK,Gallus gallus (Chicken),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; intracellular signal transduction [GO:0035556]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transport [GO:0006810]; ureteric bud development [GO:0001657]" comp123309_c0_seq3,892,46.9731,0.59044762,0,0,,6.00E-85,Q1HE26,Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4),Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0003700; GO:0005667; GO:0006351; GO:0007179,"DNA binding; cytoplasm; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway",PF03165;PF03166;,,,,,,,,,SMAD4_BOVIN,Bos taurus (Bovine),"transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp123309_c0_seq5,1380,49.5652,0.64994387,0,0,,3.00E-167,O70437,Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4),Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0043234; GO:0003700; GO:0005667; GO:0006351; GO:0007179,"DNA binding; cytoplasm; metal ion binding; nucleus; protein complex; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway",PF03165;PF03166;,9.00E-120,CHOYP_SMAD4.2.4,,,,,,,SMAD4_RAT,Rattus norvegicus (Rat),"negative regulation of protein catabolic process [GO:0042177]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp123309_c0_seq6,1299,48.6528,0.61218187,0,0,,2.00E-66,P45897,Dwarfin sma-4 (MAD protein homolog 3),Dwarfin sma-4 (MAD protein homolog 3),GO:0003677; GO:0005737; GO:0040024; GO:0046872; GO:0005634; GO:0045793; GO:0040018; GO:0046622; GO:0045732; GO:0003700; GO:0045138; GO:0005667; GO:0006351; GO:0007179,"DNA binding; cytoplasm; dauer larval development; metal ion binding; nucleus; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; positive regulation of protein catabolic process; sequence-specific DNA binding transcription factor activity; tail tip morphogenesis; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway",PF03165;PF03166;,2.00E-78,CHOYP_SMAD4.4.4,,,,,,,SMA4_CAEEL,Caenorhabditis elegans,"dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; parturition [GO:0007567]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp123309_c0_seq7,364,53.2967,0.85380761,0,0,,,,,,,,,2.00E-63,CHOYP_SMAD4.2.4,,,,,,,,, comp123315_c0_seq1,988,45.2429,0.29926199,66,26,,4.00E-51,Q9TZM3,"Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)","Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)",GO:0005524; GO:0005525; GO:0005794; GO:0048846; GO:0034613; GO:0046872; GO:0043025; GO:0004674; GO:0034976; GO:0006979; GO:0007264; GO:0048489,ATP binding; GTP binding; Golgi apparatus; axon extension involved in axon guidance; cellular protein localization; metal ion binding; neuronal cell body; protein serine/threonine kinase activity; response to endoplasmic reticulum stress; response to oxidative stress; small GTPase mediated signal transduction; synaptic vesicle transport,PF12796;PF16095;PF13855;PF00069;PF08477;,6.00E-19,CHOYP_PHUM_PHUM346120.1.1,,,,,,,LRK1_CAEEL,Caenorhabditis elegans,axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489] comp123337_c0_seq1,1436,39.9721,0.35771201,129,858,,1.00E-52,Q9R1C0,Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55),Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55),GO:0005794; GO:0071339; GO:0005737; GO:0030520; GO:0035067; GO:0006469; GO:0000122; GO:0045944; GO:0008024; GO:0006357; GO:0003700; GO:0003713; GO:0005669; GO:0033276; GO:0006366; GO:0006367; GO:0044212,Golgi apparatus; MLL1 complex; cytoplasm; intracellular estrogen receptor signaling pathway; negative regulation of histone acetylation; negative regulation of protein kinase activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive transcription elongation factor complex b; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription factor TFIID complex; transcription factor TFTC complex; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription regulatory region DNA binding,PF04658;,1.00E-67,CHOYP_TAF7.1.1,,,,,,,TAF7_MOUSE,Mus musculus (Mouse),"DNA-templated transcription, initiation [GO:0006352]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of histone acetylation [GO:0035067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp123338_c0_seq1,1214,43.1631,0.57160538,30,12,,1.00E-132,Q9UHD2,Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1),Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1),GO:0005524; GO:0007249; GO:0035666; GO:0005829; GO:0050830; GO:0051607; GO:0010008; GO:0006954; GO:0045087; GO:0019048; GO:0010629; GO:0032480; GO:0003676; GO:0043123; GO:0032727; GO:0045359; GO:0032728; GO:0033138; GO:0045944; GO:0004674; GO:0009615; GO:0034138; GO:0034142; GO:0032606,ATP binding; I-kappaB kinase/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; cytosol; defense response to Gram-positive bacterium; defense response to virus; endosome membrane; inflammatory response; innate immune response; modulation by virus of host morphology or physiology; negative regulation of gene expression; negative regulation of type I interferon production; nucleic acid binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interferon-alpha production; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-beta production; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; response to virus; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; type I interferon production,PF00069;,,,,,,,,,TBK1_HUMAN,Homo sapiens (Human),defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon production [GO:0032480]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of xenophagy [GO:1904417]; regulation of neuron death [GO:1901214]; response to virus [GO:0009615]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon production [GO:0032606]; viral process [GO:0016032] comp123338_c0_seq2,1025,43.7073,0.66976808,0,0,,3.00E-27,Q86AD7,Probable myosin light chain kinase DDB_G0271550 (EC 2.7.11.18),Probable myosin light chain kinase DDB_G0271550 (EC 2.7.11.18),GO:0005524; GO:0004687; GO:0004674,ATP binding; myosin light chain kinase activity; protein serine/threonine kinase activity,PF00069;,2.00E-32,CHOYP_IKK-EPSILON.3.3,,,,,,,MYLKB_DICDI,Dictyostelium discoideum (Slime mold), comp123338_c1_seq1,1400,38.5714,0.53900191,91,61,,5.00E-12,Q6DFJ6,Serine/threonine-protein kinase TBK1 (EC 2.7.11.1),Serine/threonine-protein kinase TBK1 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0045087; GO:0004674,ATP binding; cytoplasm; innate immune response; protein serine/threonine kinase activity,PF00069;,,,,,,,,,TBK1_XENLA,Xenopus laevis (African clawed frog),innate immune response [GO:0045087] comp123342_c0_seq1,832,36.0577,1.15508308,1280,5687,,2.00E-08,Q05306,Collagen alpha-1(X) chain,Collagen alpha-1(X) chain,GO:0005938; GO:0005581,cell cortex; collagen,PF00386;PF01391;,,,,,,,,,COAA1_MOUSE,Mus musculus (Mouse),cartilage development [GO:0051216]; endochondral ossification [GO:0001958] comp123349_c0_seq1,490,44.2857,1.08131176,0,3,,1.00E-08,P13796,Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1),Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1),GO:0002286; GO:0003779; GO:0015629; GO:0005884; GO:0051017; GO:0005509; GO:0030054; GO:0005829; GO:0031100; GO:0001891; GO:0005886; GO:0033157; GO:0032587,T cell activation involved in immune response; actin binding; actin cytoskeleton; actin filament; actin filament bundle assembly; calcium ion binding; cell junction; cytosol; organ regeneration; phagocytic cup; plasma membrane; regulation of intracellular protein transport; ruffle membrane,PF00307;PF13499;,,,,,,,,,PLSL_HUMAN,Homo sapiens (Human),actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; organ regeneration [GO:0031100]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; T cell activation involved in immune response [GO:0002286] comp123349_c0_seq2,438,45.2055,1.00856833,0,0,,2.00E-24,Q80X90,Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin),Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin),GO:0030018; GO:0005938; GO:0005737; GO:0005925; GO:0007519; GO:0001725,Z disc; cell cortex; cytoplasm; focal adhesion; skeletal muscle tissue development; stress fiber,PF00307;PF00630;,,,,,,,,,FLNB_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; skeletal muscle tissue development [GO:0007519] comp123349_c0_seq3,607,41.6804,1.0658385,0,11,,,,,,,,,1.00E-11,CHOYP_LOC100204838.1.1,,,,,,,,, comp123351_c0_seq1,786,38.8041,0.8862627,5,413,,3.00E-63,Q90W95,6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12),6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12),GO:0003874; GO:0046872; GO:0006729,6-pyruvoyltetrahydropterin synthase activity; metal ion binding; tetrahydrobiopterin biosynthetic process,PF01242;,3.00E-27,CHOYP_BRAFLDRAFT_85791.1.1,2.00E-59,ruditapes_c7628,,,,,PTPS_POERE,Poecilia reticulata (Guppy) (Acanthophacelus reticulatus),tetrahydrobiopterin biosynthetic process [GO:0006729] comp123358_c0_seq1,1566,36.5262,0.83779113,7,9,,,,,,,,,,,6.00E-76,ruditapes_c23493,,,,,,, comp123358_c0_seq2,1416,36.8644,0.82285628,0,0,,1.00E-30,O60675,Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit),Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit),GO:0007596; GO:0005654; GO:0043565; GO:0003700; GO:0006351,"blood coagulation; nucleoplasm; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF03131;,5.00E-28,CHOYP_MAFK.1.1,,,,,,,MAFK_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; nervous system development [GO:0007399]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp123361_c0_seq1,913,46.988,0.38746142,67,17,,1.00E-109,Q9HBF4,Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1),Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1),GO:0005545; GO:0005795; GO:0005783; GO:0010923; GO:0048471; GO:0005547; GO:0043325; GO:0008270,"1-phosphatidylinositol binding; Golgi stack; endoplasmic reticulum; negative regulation of phosphatase activity; perinuclear region of cytoplasm; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; zinc ion binding",PF01363;,2.00E-43,CHOYP_LOC100375831.1.1,,,,,,,ZFYV1_HUMAN,Homo sapiens (Human),cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923] comp123365_c0_seq1,1141,46.4505,0.65459181,37,190,,2.00E-61,B6RSP1,Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7) (Heart adapter protein 1),Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7) (Heart adapter protein 1),GO:0005813; GO:0005737; GO:0070097; GO:0090136; GO:0005543; GO:0005915; GO:0045218,centrosome; cytoplasm; delta-catenin binding; epithelial cell-cell adhesion; phospholipid binding; zonula adherens; zonula adherens maintenance,PF00169;PF00397;,,,,,,,,,PKHA7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cardiac muscle cell differentiation [GO:0055007]; epithelial cell-cell adhesion [GO:0090136]; regulation of heart contraction [GO:0008016]; zonula adherens maintenance [GO:0045218] comp123368_c0_seq1,1002,43.014,0.66027244,100,360,,4.00E-109,Q922H9,Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein),Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein),GO:0000775; GO:0030496; GO:0005730; GO:0008270,"chromosome, centromeric region; midbody; nucleolus; zinc ion binding",PF06524;,6.00E-95,CHOYP_ZN330.1.2,,,,,,,ZN330_MOUSE,Mus musculus (Mouse), comp123375_c1_seq2,718,45.961,0.50926473,4,0,,,,,,,,,,,3.00E-12,ruditapes_c30616,,,,,,, comp123385_c0_seq1,1035,47.0531,0.55924479,51,40,,1.00E-23,Q5YLM1,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0071926; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0004806,arachidonic acid metabolic process; endocannabinoid signaling pathway; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; triglyceride lipase activity,PF01764;,8.00E-24,CHOYP_INAE.1.1,,,,,,,DGLA_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136] comp123394_c0_seq2,958,41.3361,0.49427948,43,14,,4.00E-53,Q5RHR6,Protein broad-minded (TBC1 domain family member 32),Protein broad-minded (TBC1 domain family member 32),GO:0005097; GO:0005929; GO:0035083; GO:0005737; GO:0007275; GO:0032851,Rab GTPase activator activity; cilium; cilium axoneme assembly; cytoplasm; multicellular organismal development; positive regulation of Rab GTPase activity,PF14961;,3.00E-35,CHOYP_BROMI.2.2,,,,,,,BROMI_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275] comp123396_c0_seq2,1099,43.5851,0.59978239,0,0,,3.00E-75,Q05935,Myb-related protein A (A-Myb) (xAMYB) (Myb-like protein 1) (Myb-related protein 2) (XMYB2),Myb-related protein A (A-Myb) (xAMYB) (Myb-like protein 1) (Myb-related protein 2) (XMYB2),GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09316;PF07988;PF00249;,,,,,,,,,MYBA_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123396_c0_seq3,2893,41.2029,0.5786827,0,0,,2.00E-06,Q9UUI6,Replication termination factor 1,Replication termination factor 1,GO:0003682; GO:0008156; GO:0005634; GO:0043110; GO:0071171,chromatin binding; negative regulation of DNA replication; nucleus; rDNA spacer replication fork barrier binding; site-specific DNA replication termination at RTS1 barrier,PF00249;,,,,,,,,,RTF_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),negative regulation of DNA replication [GO:0008156]; site-specific DNA replication termination at RTS1 barrier [GO:0071171] comp123396_c0_seq4,2766,41.6847,0.54983117,0,0,,2.00E-77,P06876,Transcriptional activator Myb (Proto-oncogene c-Myb),Transcriptional activator Myb (Proto-oncogene c-Myb),GO:0030183; GO:0003677; GO:0000082; GO:0006816; GO:0003682; GO:0048566; GO:0048872; GO:0001701; GO:0005654; GO:0045944; GO:0003700; GO:0048538; GO:0006351,"B cell differentiation; DNA binding; G1/S transition of mitotic cell cycle; calcium ion transport; chromatin binding; embryonic digestive tract development; homeostasis of number of cells; in utero embryonic development; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; thymus development; transcription, DNA-dependent",PF09316;PF07988;PF00249;,1.00E-65,CHOYP_MYBA.1.1,,,,,,,MYB_MOUSE,Mus musculus (Mouse),"B cell differentiation [GO:0030183]; calcium ion transport [GO:0006816]; cellular response to interleukin-6 [GO:0071354]; chromatin remodeling [GO:0006338]; embryonic digestive tract development [GO:0048566]; G1/S transition of mitotic cell cycle [GO:0000082]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of T-helper cell differentiation [GO:0045624]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; spleen development [GO:0048536]; stem cell division [GO:0017145]; thymus development [GO:0048538]" comp123397_c1_seq1,1304,42.1012,0.47023917,96,246,,2.00E-38,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp123399_c0_seq1,578,35.1211,0.2810688,16,54,,2.00E-06,P83425,Heavy metal-binding protein HIP,Heavy metal-binding protein HIP,GO:0005576; GO:0046872,extracellular region; metal ion binding,PF00386;,,,,,,,,,HIP_MYTED,Mytilus edulis (Blue mussel), comp123400_c1_seq1,409,40.3423,0.36444662,15,38,,2.00E-45,Q17R89,Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2),Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2),GO:0005096; GO:0005829; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF03114;PF00620;,,,,,,,,,RHG44_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp123418_c0_seq1,871,41.791,0.9491169,5,144,,6.00E-16,Q6DJC8,Transmembrane protein 53-B,Transmembrane protein 53-B,GO:0016021,integral to membrane,PF05705;,,,,,,,,,TM53B_XENLA,Xenopus laevis (African clawed frog), comp123420_c2_seq1,1417,35.6387,0.49254793,148,21,,2.00E-12,Q58DA1,Sperm flagellar protein 1,Sperm flagellar protein 1,GO:0035085; GO:0005856,cilium axoneme; cytoskeleton,PF06294;,,,,,,,,,SPEF1_BOVIN,Bos taurus (Bovine), comp123422_c0_seq3,445,42.4719,0.76475009,0,27,,,,,,,,,,,8.00E-24,ruditapes_c14600,,,,,,, comp123426_c0_seq1,943,44.6448,0.75426986,3,0,,1.00E-28,P76052,p-aminobenzoyl-glutamate hydrolase subunit B (EC 3.5.1.-) (PABA-GLU hydrolase) (PGH),p-aminobenzoyl-glutamate hydrolase subunit B (EC 3.5.1.-) (PABA-GLU hydrolase) (PGH),GO:0005737; GO:0046657; GO:0071713,cytoplasm; folic acid catabolic process; para-aminobenzoyl-glutamate hydrolase activity,PF01546;,,,,,,,,,ABGB_ECOLI,Escherichia coli (strain K12),folic acid catabolic process [GO:0046657] comp123426_c0_seq2,1023,44.6725,0.74917284,0,37,,2.00E-79,A3KG59,Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),GO:0016787,hydrolase activity,PF07687;PF01546;,7.00E-12,CHOYP_P20D2.2.2,,,,,,,P20D2_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268] comp123428_c1_seq1,820,40.6098,1.03729127,3,186,,7.00E-17,Q6NT32,Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin),Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin),GO:0004091; GO:0005576,carboxylesterase activity; extracellular region,PF00135;,,,,,,,,,EST5A_HUMAN,Homo sapiens (Human), comp123430_c0_seq1,229,42.7948,0.71334989,8,19,,6.00E-07,A8X633,APC-related protein 1,APC-related protein 1,GO:0016055; GO:0005912; GO:0008356; GO:0005938; GO:0007049; GO:0048598; GO:0007492; GO:0030178; GO:0005634; GO:0015031,Wnt receptor signaling pathway; adherens junction; asymmetric cell division; cell cortex; cell cycle; embryonic morphogenesis; endoderm development; negative regulation of Wnt receptor signaling pathway; nucleus; protein transport,,,,,,,,,,APR1_CAEBR,Caenorhabditis briggsae,asymmetric cell division [GO:0008356]; cell cycle [GO:0007049]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; embryonic morphogenesis [GO:0048598]; endoderm development [GO:0007492]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of Wnt signaling pathway [GO:0030178]; pattern specification process [GO:0007389]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; regulation of cell differentiation [GO:0045595]; Wnt signaling pathway [GO:0016055] comp123430_c0_seq2,1231,43.948,0.82506068,60,165,,1.00E-58,P25054,Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5),Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5),GO:0033077; GO:0005912; GO:0009952; GO:0009798; GO:0044295; GO:0007409; GO:0030877; GO:0060070; GO:0007155; GO:0007050; GO:0016477; GO:0006921; GO:0005813; GO:0051276; GO:0005881; GO:0031122; GO:0005829; GO:0009953; GO:0001942; GO:0001822; GO:0000776; GO:0030027; GO:0016328; GO:0007091; GO:0035371; GO:0051010; GO:0000281; GO:0007094; GO:0046716; GO:0043409; GO:0043066; GO:0090090; GO:0008285; GO:0045736; GO:0060770; GO:0007026; GO:0042483; GO:0005634; GO:0043065; GO:0045785; GO:0051781; GO:0030335; GO:0030858; GO:0031116; GO:0045732; GO:0031274; GO:0006461; GO:0019887; GO:0009954; GO:0051988; GO:0051171; GO:0045667; GO:0045670; GO:0006974; GO:0060041; GO:0032587; GO:0035019; GO:0048538; GO:0005923; GO:0070830,T cell differentiation in thymus; adherens junction; anterior/posterior pattern specification; axis specification; axonal growth cone; axonogenesis; beta-catenin destruction complex; canonical Wnt receptor signaling pathway; cell adhesion; cell cycle arrest; cell migration; cellular component disassembly involved in execution phase of apoptosis; centrosome; chromosome organization; cytoplasmic microtubule; cytoplasmic microtubule organization; cytosol; dorsal/ventral pattern formation; hair follicle development; kidney development; kinetochore; lamellipodium; lateral plasma membrane; metaphase/anaphase transition of mitotic cell cycle; microtubule plus end; microtubule plus-end binding; mitotic cytokinesis; mitotic spindle assembly checkpoint; muscle cell cellular homeostasis; negative regulation of MAPK cascade; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of epithelial cell proliferation involved in prostate gland development; negative regulation of microtubule depolymerization; negative regulation of odontogenesis; nucleus; positive regulation of apoptotic process; positive regulation of cell adhesion; positive regulation of cell division; positive regulation of cell migration; positive regulation of epithelial cell differentiation; positive regulation of microtubule polymerization; positive regulation of protein catabolic process; positive regulation of pseudopodium assembly; protein complex assembly; protein kinase regulator activity; proximal/distal pattern formation; regulation of attachment of spindle microtubules to kinetochore; regulation of nitrogen compound metabolic process; regulation of osteoblast differentiation; regulation of osteoclast differentiation; response to DNA damage stimulus; retina development in camera-type eye; ruffle membrane; somatic stem cell maintenance; thymus development; tight junction; tight junction assembly,PF05972;PF05956;PF05923;PF16689;PF00514;PF05937;PF05924;,,,,,,,,,APC_HUMAN,Homo sapiens (Human),beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; canonical Wnt signaling pathway [GO:0060070]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment or maintenance of cell polarity [GO:0007163]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of glutamate metabolic process [GO:2000211]; regulation of microtubule-based process [GO:0032886]; response to alcohol [GO:0097305]; response to drug [GO:0042493]; Wnt signaling pathway [GO:0016055] comp123430_c1_seq2,1517,45.9459,0.63754228,87,186,,,,,,,,,2.00E-40,CHOYP_APC.1.2,,,,,,,,, comp123433_c0_seq1,389,40.3599,0.44318475,0,3,,5.00E-18,Q5EDC3,Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H),Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H),GO:0005524; GO:0051301; GO:0005929; GO:0004693; GO:0005737; GO:0007275; GO:0005634,ATP binding; cell division; cilium; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; multicellular organismal development; nucleus,PF00069;,,,,,,,,,CDK20_MACMU,Macaca mulatta (Rhesus macaque),cell cycle [GO:0007049]; cell division [GO:0051301]; multicellular organism development [GO:0007275] comp123433_c0_seq2,466,40.1288,0.32162683,8,26,,6.00E-96,P51166,Cyclin-dependent kinase 5 (EC 2.7.11.22) (Cell division protein kinase 5) (Neuronal cyclin-dependent kinase 5),Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Neuronal cyclin-dependent kinase 5),GO:0005524; GO:0005176; GO:0043125; GO:0030549; GO:0030424; GO:0051301; GO:0030054; GO:0004693; GO:0005737; GO:0030425; GO:0009790; GO:0030426; GO:0030027; GO:0016020; GO:0031594; GO:0031175; GO:0043025; GO:0005634; GO:0043204; GO:0043525; GO:0014069; GO:0045211; GO:0004674; GO:0061001; GO:0050321,ATP binding; ErbB-2 class receptor binding; ErbB-3 class receptor binding; acetylcholine receptor activator activity; axon; cell division; cell junction; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; dendrite; embryo development; growth cone; lamellipodium; membrane; neuromuscular junction; neuron projection development; neuronal cell body; nucleus; perikaryon; positive regulation of neuron apoptotic process; postsynaptic density; postsynaptic membrane; protein serine/threonine kinase activity; regulation of dendritic spine morphogenesis; tau-protein kinase activity,PF00069;,2.00E-98,CHOYP_CDK5.1.1,,,,,,,CDK5_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of dendritic spine morphogenesis [GO:0061001]; rhythmic process [GO:0048511] comp123433_c2_seq1,267,40.4494,0.49265397,2,23,,2.00E-27,Q01917,Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23),Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23),GO:0005524; GO:0008353; GO:0051301; GO:0004693; GO:0007067,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cell division; cyclin-dependent protein serine/threonine kinase activity; mitosis,PF00069;,2.00E-74,CHOYP_CDK5.1.1,,,,,,,CDC2H_CRIFA,Crithidia fasciculata,cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp123435_c0_seq1,1186,46.6273,0.71939445,56,219,,9.00E-112,Q95J75,Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32),Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,1.00E-54,CHOYP_LOC100648519.1.1,,,,,,,MFTC_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),mitochondrial transport [GO:0006839] comp123437_c0_seq1,828,40.5797,0.27033628,54,84,,1.00E-106,Q8VEE0,Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Ribulose-5-phosphate-epimerase),Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Ribulose-5-phosphate-epimerase),GO:0046872; GO:0006098; GO:0004750,metal ion binding; pentose-phosphate shunt; ribulose-phosphate 3-epimerase activity,PF00834;,2.00E-119,CHOYP_LOC100370410.1.1,,,,,,,RPE_MOUSE,Mus musculus (Mouse),"carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]" comp123443_c0_seq1,647,38.949,0.56969095,48,175,,3.00E-44,Q76FK4,Nucleolar protein 8 (Nucleolar protein Nop132),Nucleolar protein 8 (Nucleolar protein Nop132),GO:0006260; GO:0003723; GO:0005737; GO:0005730; GO:0000166; GO:0030307; GO:0006364,DNA replication; RNA binding; cytoplasm; nucleolus; nucleotide binding; positive regulation of cell growth; rRNA processing,PF00076;,,,,,,,,,NOL8_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; positive regulation of cell growth [GO:0030307]; rRNA processing [GO:0006364] comp123447_c0_seq2,604,42.7152,0.47288489,0,0,,1.00E-45,P15732,Ubiquitin-conjugating enzyme E2-16 kDa (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Ubiquitin-conjugating enzyme E2-16 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 5) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0034605; GO:0000502; GO:0000209; GO:0004842,ATP binding; cellular response to heat; proteasome complex; protein polyubiquitination; ubiquitin-protein ligase activity,PF00179;,5.00E-17,CHOYP_UB2D2.1.1,3.00E-12,ruditapes_c12050,,,,,UBC5_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to heat [GO:0034605]; protein polyubiquitination [GO:0000209] comp123454_c1_seq1,794,32.6196,0.61738449,35,196,,,,,,,,,,,8.00E-14,ruditapes_c27792,,,,,,, comp123456_c1_seq1,825,49.4545,0.55576196,38,72,,1.00E-114,Q8NEZ4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,8.00E-99,CHOYP_MLL2.1.1,,,,,,,MLL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123460_c0_seq1,396,40.404,0.6204134,3,60,,2.00E-13,Q9VCX1,Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco),Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco),GO:0007186; GO:0005092; GO:0005096; GO:0045179; GO:0016324; GO:0055059; GO:0008105; GO:0032291; GO:0007049; GO:0030866; GO:0007303; GO:0050832; GO:0008069; GO:0000578; GO:0014045; GO:0060857; GO:0003015; GO:0007310; GO:0005886; GO:0005057; GO:0008277; GO:0009786; GO:0009408; GO:0006979; GO:0042594; GO:0019991; GO:0038032; GO:0007419,"G-protein coupled receptor signaling pathway; GDP-dissociation inhibitor activity; GTPase activator activity; apical cortex; apical plasma membrane; asymmetric neuroblast division; asymmetric protein localization; axon ensheathment in central nervous system; cell cycle; cortical actin cytoskeleton organization; cytoplasmic transport, nurse cell to oocyte; defense response to fungus; dorsal/ventral axis specification, ovarian follicular epithelium; embryonic axis specification; establishment of endothelial blood-brain barrier; establishment of glial blood-brain barrier; heart process; oocyte dorsal/ventral axis specification; plasma membrane; receptor signaling protein activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of asymmetric cell division; response to heat; response to oxidative stress; response to starvation; septate junction assembly; termination of G-protein coupled receptor signaling pathway; ventral cord development",PF00595;PF02196;PF00615;,8.00E-13,CHOYP_LOC100889318.1.1,,,,,,,RGS_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization [GO:0008105]; axon ensheathment in central nervous system [GO:0032291]; cell cycle [GO:0007049]; cortical actin cytoskeleton organization [GO:0030866]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; defense response to fungus [GO:0050832]; dorsal/ventral axis specification, ovarian follicular epithelium [GO:0008069]; embryonic axis specification [GO:0000578]; establishment of endothelial blood-brain barrier [GO:0014045]; establishment of glial blood-brain barrier [GO:0060857]; glial cell differentiation [GO:0010001]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; oocyte dorsal/ventral axis specification [GO:0007310]; regulation of asymmetric cell division [GO:0009786]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to starvation [GO:0042594]; septate junction assembly [GO:0019991]; ventral cord development [GO:0007419]" comp123461_c0_seq1,1044,40.5172,0.47257313,56,229,,4.00E-66,Q4QRH7,Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16),Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16),GO:0016021; GO:0005778; GO:0007031,integral to membrane; peroxisomal membrane; peroxisome organization,PF08610;,,,,,,,,,PEX16_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),peroxisome organization [GO:0007031] comp123468_c0_seq1,1075,38.5116,0.37954177,2233,7152,,2.00E-113,Q5RE15,26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (Fragment),26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (Fragment),GO:0022624; GO:0005838; GO:0006508,proteasome accessory complex; proteasome regulatory particle; proteolysis,PF10075;,4.00E-174,CHOYP_LOC100372505.2.2,3.00E-90,ruditapes_c28069,,,,,PSMD8_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),proteolysis [GO:0006508] comp123469_c0_seq1,510,45.098,0.47169412,15,63,,1.00E-51,Q4R3U7,Glycosyltransferase 8 domain-containing protein 2 (EC 2.4.1.-),Glycosyltransferase 8 domain-containing protein 2 (EC 2.4.1.-),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF01501;,,,,,,,,,GL8D2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp123488_c0_seq1,623,35.7945,0.67096947,4,31,,2.00E-08,Q4A3R3,Deleted in malignant brain tumors 1 protein (Hensin),Deleted in malignant brain tumors 1 protein (Hensin),GO:0030154; GO:0005576; GO:0019898; GO:0016021; GO:0007275; GO:0015031; GO:0005044; GO:0030658; GO:0035375; GO:0042589,cell differentiation; extracellular region; extrinsic to membrane; integral to membrane; multicellular organismal development; protein transport; scavenger receptor activity; transport vesicle membrane; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,,,,,,,,,DMBT1_PIG,Sus scrofa (Pig),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein transport [GO:0015031] comp123488_c0_seq2,836,34.4498,0.66590518,14,40,,1.00E-07,A5PJQ2,Scavenger receptor class A member 5,Scavenger receptor class A member 5,GO:0009986; GO:0006879; GO:0034605; GO:0070287; GO:0005887; GO:0034755; GO:0070207; GO:0005044,cell surface; cellular iron ion homeostasis; cellular response to heat; ferritin receptor activity; integral to plasma membrane; iron ion transmembrane transport; protein homotrimerization; scavenger receptor activity,PF01391;PF00530;,,,,,,,,,SCAR5_BOVIN,Bos taurus (Bovine),cellular iron ion homeostasis [GO:0006879]; cellular response to heat [GO:0034605]; endocytosis [GO:0006897]; iron ion transmembrane transport [GO:0034755]; protein homotrimerization [GO:0070207]; regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468] comp123489_c0_seq1,1002,44.1118,0.74052576,14,196,,,,,,,,,6.00E-32,CHOYP_LOC593558.4.4,,,,,,,,, comp123491_c0_seq3,636,38.0503,0.52241791,29,119,,5.00E-12,Q5BK01,Methyltransferase-like protein 24 (EC 2.1.1.-),Methyltransferase-like protein 24 (EC 2.1.1.-),GO:0005576; GO:0008168,extracellular region; methyltransferase activity,PF13383;,,,,,,,,,MET24_RAT,Rattus norvegicus (Rat), comp123498_c0_seq1,654,34.4037,0.83399845,0,0,,1.00E-12,Q7T2V2,Cytosolic sulfotransferase 3 (EC 2.8.2.-) (SULT1 ST3),Cytosolic sulfotransferase 3 (EC 2.8.2.-) (SULT1 ST3),GO:0006584; GO:0005737; GO:0008202; GO:0008146; GO:0006805,catecholamine metabolic process; cytoplasm; steroid metabolic process; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1S3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805] comp123498_c0_seq2,699,34.7639,0.81217747,0,0,,3.00E-17,P19217,"Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring)","Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring)",GO:0005737; GO:0008210; GO:0004304; GO:0005496; GO:0050294,cytoplasm; estrogen metabolic process; estrone sulfotransferase activity; steroid binding; steroid sulfotransferase activity,PF00685;,,,,,,,,,ST1E1_BOVIN,Bos taurus (Bovine),estrogen metabolic process [GO:0008210] comp123498_c0_seq3,649,34.8228,0.82090336,2,9,,7.00E-08,O35403,Amine sulfotransferase (EC 2.8.2.3) (SULT-X2) (Sulfotransferase 3A1) (ST3A1),Amine sulfotransferase (EC 2.8.2.3) (SULT-X2) (Sulfotransferase 3A1) (ST3A1),GO:0047685; GO:0005737,amine sulfotransferase activity; cytoplasm,PF00685;,,,,,,,,,ST3A1_MOUSE,Mus musculus (Mouse),sulfation [GO:0051923] comp123498_c0_seq4,604,34.6026,0.83795244,0,0,,,,,,,,,,,3.00E-12,ruditapes_c20565,,,,,,, comp123502_c0_seq3,989,41.456,0.32992964,0,0,,7.00E-43,Q9QYT7,Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (MGpi1p) (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q),Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (MGpi1p) (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q),GO:0006506; GO:0000506; GO:0016021; GO:0017176,GPI anchor biosynthetic process; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to membrane; phosphatidylinositol N-acetylglucosaminyltransferase activity,PF05024;,1.00E-22,CHOYP_LOC100016710.1.1,,,,,,,PIGQ_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp123506_c0_seq1,1246,35.8748,0.41590955,2,0,,2.00E-07,Q9VCP0,Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA),Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA),GO:0003677; GO:0070449; GO:0016021; GO:0007275; GO:0032968; GO:0006368,DNA binding; elongin complex; integral to membrane; multicellular organismal development; positive regulation of transcription elongation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter,PF06881;PF08711;,,,,,,,,,ELOA1_DROME,Drosophila melanogaster (Fruit fly),imaginal disc-derived wing vein specification [GO:0007474]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp123508_c0_seq1,1433,42.4285,0.90767462,2,300,female>male,6.00E-152,O88533,Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC),Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC),GO:0016597; GO:0004058; GO:0030424; GO:0006520; GO:0071312; GO:0035690; GO:0071363; GO:0007623; GO:0042416; GO:0033076; GO:0010259; GO:0043025; GO:0052314; GO:0030170; GO:0046684; GO:0009636; GO:0042427; GO:0008021; GO:0015842,amino acid binding; aromatic-L-amino-acid decarboxylase activity; axon; cellular amino acid metabolic process; cellular response to alkaloid; cellular response to drug; cellular response to growth factor stimulus; circadian rhythm; dopamine biosynthetic process; isoquinoline alkaloid metabolic process; multicellular organismal aging; neuronal cell body; phytoalexin metabolic process; pyridoxal phosphate binding; response to pyrethroid; response to toxic substance; serotonin biosynthetic process; synaptic vesicle; synaptic vesicle amine transport,PF00282;,6.00E-40,CHOYP_DDC.1.1,,,,,,,DDC_MOUSE,Mus musculus (Mouse),aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; cellular amino acid metabolic process [GO:0006520]; cellular response to alkaloid [GO:0071312]; cellular response to drug [GO:0035690]; cellular response to growth factor stimulus [GO:0071363]; circadian rhythm [GO:0007623]; dopamine biosynthetic process [GO:0042416]; isoquinoline alkaloid metabolic process [GO:0033076]; multicellular organism aging [GO:0010259]; phytoalexin metabolic process [GO:0052314]; response to pyrethroid [GO:0046684]; response to toxic substance [GO:0009636]; serotonin biosynthetic process [GO:0042427] comp123516_c0_seq1,662,32.7795,0.33809358,107,1019,,5.00E-36,Q9CQW7,"Apoptogenic protein 1, mitochondrial (APOP-1)","Apoptogenic protein 1, mitochondrial (APOP-1)",GO:0097193; GO:0005739; GO:0043280; GO:0090200; GO:0034393,intrinsic apoptotic signaling pathway; mitochondrion; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of release of cytochrome c from mitochondria; positive regulation of smooth muscle cell apoptotic process,PF10231;,,,,,,,,,APOP1_MOUSE,Mus musculus (Mouse),intrinsic apoptotic signaling pathway [GO:0097193]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of smooth muscle cell apoptotic process [GO:0034393] comp123534_c0_seq1,1276,45.3762,0.34295292,72,41,,2.00E-177,Q9BYV1,"Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)","Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)",GO:0047305; GO:0019481; GO:0008453; GO:0016223; GO:0019265; GO:0009436; GO:0005759; GO:0045429; GO:0030170; GO:0006206; GO:0046135,"(R)-3-amino-2-methylpropionate-pyruvate transaminase activity; L-alanine catabolic process, by transamination; alanine-glyoxylate transaminase activity; beta-alanine-pyruvate transaminase activity; glycine biosynthetic process, by transamination of glyoxylate; glyoxylate catabolic process; mitochondrial matrix; positive regulation of nitric oxide biosynthetic process; pyridoxal phosphate binding; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process",PF00202;,0,CHOYP_TRIADDRAFT_63204.1.2,3.00E-16,ruditapes_c28944,5.00E-88,CU686151.p.cg.6,4,,AGT2_HUMAN,Homo sapiens (Human),"glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process, by transamination [GO:0019481]; positive regulation of nitric oxide biosynthetic process [GO:0045429]" comp123538_c0_seq2,670,42.9851,0.65633246,11,9,,2.00E-68,Q8UVC3,Inversin,Inversin,GO:0016055; GO:0005737; GO:0005856; GO:0007275,Wnt receptor signaling pathway; cytoplasm; cytoskeleton; multicellular organismal development,PF12796;PF00612;,1.00E-70,CHOYP_INVS.3.6,,,,,,,INVS_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp123540_c0_seq1,884,45.1357,0.3565857,19,14,,5.00E-73,Q9VR07,Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A),Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A),GO:0016021; GO:0005328; GO:0005034; GO:0042066; GO:0009881; GO:0005886; GO:0047484; GO:0019226,integral to membrane; neurotransmitter:sodium symporter activity; osmosensor activity; perineurial glial growth; photoreceptor activity; plasma membrane; regulation of response to osmotic stress; transmission of nerve impulse,PF00209;,6.00E-82,CHOYP_BRAFLDRAFT_213699.1.1,,,,,,,INE_DROME,Drosophila melanogaster (Fruit fly),glial cell growth [GO:0042065]; multicellular organismal water homeostasis [GO:0050891]; neurotransmitter transport [GO:0006836]; perineurial glial growth [GO:0042066]; regulation of response to osmotic stress [GO:0047484]; response to water deprivation [GO:0009414]; transmission of nerve impulse [GO:0019226]; transport [GO:0006810] comp123540_c0_seq2,234,43.5897,0.27273225,6,3,,1.00E-17,O88575,Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B),Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B),GO:0016324; GO:0005887; GO:0005328; GO:0005215,apical plasma membrane; integral to plasma membrane; neurotransmitter:sodium symporter activity; transporter activity,PF00209;,,,,,,,,,S620B_MOUSE,Mus musculus (Mouse),"glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp123540_c0_seq3,382,43.7173,0.27514556,4,0,,1.00E-23,Q9UN76,Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14),Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14),GO:0015171; GO:0031526; GO:0006520; GO:0016021; GO:0005328; GO:0005886; GO:0009636,amino acid transmembrane transporter activity; brush border membrane; cellular amino acid metabolic process; integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane; response to toxic substance,PF00209;,,,,,,,,,S6A14_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; transport [GO:0006810] comp123540_c1_seq1,639,44.6009,0.34679888,26,0,,4.00E-32,Q9VR07,Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A),Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A),GO:0016021; GO:0005328; GO:0005034; GO:0042066; GO:0009881; GO:0005886; GO:0047484; GO:0019226,integral to membrane; neurotransmitter:sodium symporter activity; osmosensor activity; perineurial glial growth; photoreceptor activity; plasma membrane; regulation of response to osmotic stress; transmission of nerve impulse,PF00209;,,,,,,,,,INE_DROME,Drosophila melanogaster (Fruit fly),glial cell growth [GO:0042065]; multicellular organismal water homeostasis [GO:0050891]; neurotransmitter transport [GO:0006836]; perineurial glial growth [GO:0042066]; regulation of response to osmotic stress [GO:0047484]; response to water deprivation [GO:0009414]; transmission of nerve impulse [GO:0019226]; transport [GO:0006810] comp123542_c2_seq1,1465,38.9078,0.33318197,25,230,,2.00E-127,Q9Y673,Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog),Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog),GO:0007368; GO:0006488; GO:0004581; GO:0005789; GO:0016021; GO:0004576; GO:0043687; GO:0018279,determination of left/right symmetry; dolichol-linked oligosaccharide biosynthetic process; dolichyl-phosphate beta-glucosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; oligosaccharyl transferase activity; post-translational protein modification; protein N-linked glycosylation via asparagine,PF00535;,6.00E-110,CHOYP_ALG5.1.1,,,,,,,ALG5_HUMAN,Homo sapiens (Human),determination of left/right symmetry [GO:0007368]; dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269] comp123548_c0_seq1,1087,38.4545,0.46052949,65,560,,3.00E-86,Q9CQ02,COMM domain-containing protein 4,COMM domain-containing protein 4,GO:0005737,cytoplasm,PF07258;,8.00E-69,CHOYP_BRAFLDRAFT_116088.2.2,3.00E-14,ruditapes2_c2182,,,,,COMD4_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123558_c0_seq1,802,40.2743,1.15778373,56,109,,2.00E-09,P02637,Sarcoplasmic calcium-binding protein (SCP),Sarcoplasmic calcium-binding protein (SCP),GO:0005509,calcium ion binding,,,,,,,,,,SCP_MIZYE,Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis), comp123559_c0_seq1,523,43.9771,0.51571087,13,6,,3.00E-10,Q28EM8,LETM1 domain-containing protein 1,LETM1 domain-containing protein 1,GO:0016021; GO:0005741,integral to membrane; mitochondrial outer membrane,PF07766;,,,,,,,,,LTMD1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp123569_c0_seq2,407,42.0147,0.79576964,4,0,,,,,,,,,2.00E-27,CHOYP_BRAFLDRAFT_128033.1.2,,,,,,,,, comp123569_c1_seq1,579,46.6321,0.47206699,12,111,,3.00E-45,P25145,Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA),Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA),GO:0016491,oxidoreductase activity,PF00106;,1.00E-37,CHOYP_BRAFLDRAFT_128033.2.2,,,,,,,Y432_LISMO,Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e), comp123580_c0_seq1,1447,42.4326,1.11910745,4063,57653,,,,,,,,,,,2.00E-11,ruditapes2_c2772,,,,,,, comp123584_c0_seq3,547,40.2194,0.45930922,0,22,,4.00E-13,P78560,Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),GO:0006977; GO:0071260; GO:0005737; GO:0008625; GO:0005634; GO:0042981,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular response to mechanical stimulus; cytoplasm; extrinsic apoptotic signaling pathway via death domain receptors; nucleus; regulation of apoptotic process",PF00619;PF00531;,,,,,,,,,CRADD_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]" comp123585_c1_seq1,1418,41.4669,0.51390725,134,61,,3.00E-78,Q8CG46,Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (mSMC5) (Protein expressed in male leptotene and zygotene spermatocytes 453) (MLZ-453),Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (mSMC5) (Protein expressed in male leptotene and zygotene spermatocytes 453) (MLZ-453),GO:0005524; GO:0016605; GO:0030915; GO:0051301; GO:0090398; GO:0000781; GO:0000724; GO:0007067; GO:0034184; GO:0045842; GO:0000722,"ATP binding; PML body; Smc5-Smc6 complex; cell division; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; mitosis; positive regulation of maintenance of mitotic sister chromatid cohesion; positive regulation of mitotic metaphase/anaphase transition; telomere maintenance via recombination",PF02463;,,,,,,,,,SMC5_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722] comp123592_c0_seq1,869,46.8354,0.60927393,16,8,,5.00E-10,Q08DL1,Zinc finger CCHC domain-containing protein 12,Zinc finger CCHC domain-containing protein 12,GO:0003676; GO:0006355; GO:0006351; GO:0008270,"nucleic acid binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF14893;,,,,,,,,,ZCH12_BOVIN,Bos taurus (Bovine),"BMP signaling pathway [GO:0030509]; transcription, DNA-templated [GO:0006351]" comp123600_c0_seq1,885,48.2486,0.39080814,12,70,,,,,,,,,8.00E-11,CHOYP_LOC100929680.2.2,,,,,,,,, comp123600_c2_seq1,312,47.4359,0.22880352,10,3,,,,,,,,,1.00E-21,CHOYP_CO6A5.1.6,,,,,,,,, comp123602_c0_seq1,443,36.3431,0.41149422,9,21,,,,,,,,,,,2.00E-50,ruditapes_c8200,,,,,,, comp123607_c0_seq1,1120,42.2321,0.32074418,65,45,,2.00E-80,P0C5Y8,Alsin (Amyotrophic lateral sclerosis 2 protein homolog),Alsin (Amyotrophic lateral sclerosis 2 protein homolog),GO:0017137; GO:0017112; GO:0030676; GO:0016601; GO:0030424; GO:0007409; GO:0001662; GO:0008219; GO:0005813; GO:0005829; GO:0030425; GO:0043197; GO:0005769; GO:0016197; GO:0030426; GO:0001701; GO:0030027; GO:0007626; GO:0016020; GO:0007528; GO:0043025; GO:0005543; GO:0032855; GO:0014069; GO:0043234; GO:0042803; GO:0008104; GO:0043539; GO:0001881; GO:0032313; GO:0051036; GO:0006979; GO:0001726; GO:0035249; GO:0031982; GO:0016050,"Rab GTPase binding; Rab guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; axon; axonogenesis; behavioral fear response; cell death; centrosome; cytosol; dendrite; dendritic spine; early endosome; endosomal transport; growth cone; in utero embryonic development; lamellipodium; locomotory behavior; membrane; neuromuscular junction development; neuronal cell body; phospholipid binding; positive regulation of Rac GTPase activity; postsynaptic density; protein complex; protein homodimerization activity; protein localization; protein serine/threonine kinase activator activity; receptor recycling; regulation of Rab GTPase activity; regulation of endosome size; response to oxidative stress; ruffle; synaptic transmission, glutamatergic; vesicle; vesicle organization",PF02493;PF00415;PF00621;PF02204;,4.00E-53,CHOYP_ALS2.1.3,,,,,,,ALS2_RAT,Rattus norvegicus (Rat),"axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050]" comp123614_c0_seq1,1711,45.5289,0.71161194,4,11,,2.00E-46,Q6P5E8,Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta),Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta),GO:0005524; GO:0003951; GO:0019933; GO:0005856; GO:0005829; GO:0004143; GO:0046872; GO:0016607; GO:0005886; GO:0070528; GO:0007205; GO:0033198; GO:0070493,ATP binding; NAD+ kinase activity; cAMP-mediated signaling; cytoskeleton; cytosol; diacylglycerol kinase activity; metal ion binding; nuclear speck; plasma membrane; protein kinase C signaling cascade; protein kinase C-activating G-protein coupled receptor signaling pathway; response to ATP; thrombin receptor signaling pathway,PF00130;PF00609;PF00781;PF00788;,,,,,,,,,DGKQ_MOUSE,Mus musculus (Mouse),cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ATP [GO:0033198]; thrombin receptor signaling pathway [GO:0070493] comp123614_c0_seq2,1699,45.6151,0.71357993,3,0,,1.00E-46,Q6P5E8,Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta),Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta),GO:0005524; GO:0003951; GO:0019933; GO:0005856; GO:0005829; GO:0004143; GO:0046872; GO:0016607; GO:0005886; GO:0070528; GO:0007205; GO:0033198; GO:0070493,ATP binding; NAD+ kinase activity; cAMP-mediated signaling; cytoskeleton; cytosol; diacylglycerol kinase activity; metal ion binding; nuclear speck; plasma membrane; protein kinase C signaling cascade; protein kinase C-activating G-protein coupled receptor signaling pathway; response to ATP; thrombin receptor signaling pathway,PF00130;PF00609;PF00781;PF00788;,,,,,,,,,DGKQ_MOUSE,Mus musculus (Mouse),cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ATP [GO:0033198]; thrombin receptor signaling pathway [GO:0070493] comp123614_c0_seq3,843,46.6192,0.62924788,0,0,,4.00E-09,P13678,Protein kinase C (PKC) (EC 2.7.11.13) (dPKC98F),Protein kinase C (PKC) (EC 2.7.11.13) (dPKC98F),GO:0005524; GO:0007030; GO:0035556; GO:0034389; GO:0046872; GO:0008285; GO:0048812; GO:0004697; GO:0045471,ATP binding; Golgi organization; intracellular signal transduction; lipid particle organization; metal ion binding; negative regulation of cell proliferation; neuron projection morphogenesis; protein kinase C activity; response to ethanol,PF00130;PF00069;PF00433;,4.00E-103,CHOYP_LOC100900935.1.1,,,,,,,KPC3_DROME,Drosophila melanogaster (Fruit fly),dorsal/ventral axis specification [GO:0009950]; Golgi organization [GO:0007030]; I-kappaB phosphorylation [GO:0007252]; lipid particle organization [GO:0034389]; long-term memory [GO:0007616]; negative regulation of cell proliferation [GO:0008285]; neuron projection morphogenesis [GO:0048812]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptide hormone secretion [GO:0090277]; protein phosphorylation [GO:0006468]; response to ethanol [GO:0045471] comp123614_c0_seq4,1202,45.2579,0.64677464,2,0,,3.00E-10,Q01583,Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),GO:0005524; GO:0003951; GO:0005509; GO:0004143; GO:0035556; GO:0007205,ATP binding; NAD+ kinase activity; calcium ion binding; diacylglycerol kinase activity; intracellular signal transduction; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF14513;PF00609;PF00781;,,,4.00E-90,ruditapes_c19437,,,,,DGK1_DROME,Drosophila melanogaster (Fruit fly),intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313] comp123618_c0_seq1,570,39.8246,0.4470731,15,34,,7.00E-07,Q9D0P5,Pygopus homolog 1,Pygopus homolog 1,GO:0016055; GO:0001822; GO:0005634; GO:0045944; GO:0009791; GO:0034504; GO:0008270,Wnt receptor signaling pathway; kidney development; nucleus; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein localization to nucleus; zinc ion binding,PF00628;,,,,,,,,,PYGO1_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244]; kidney development [GO:0001822]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein localization to nucleus [GO:0034504]; spermatid development [GO:0007286]; spermatid nucleus differentiation [GO:0007289]; Wnt signaling pathway [GO:0016055] comp123622_c0_seq1,844,35.0711,0.27214209,49,39,,5.00E-08,Q7ZV90,ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1),ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006310; GO:0006281; GO:0005739; GO:0005634; GO:0000723,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA recombination; DNA repair; mitochondrion; nucleus; telomere maintenance,PF05970;,,,,,,,,,PIF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; telomere maintenance [GO:0000723] comp123636_c0_seq1,761,35.3482,0.42689149,7381,12411,,8.00E-58,P84029,Cytochrome c-2 (Cytochrome c-proximal),Cytochrome c-2 (Cytochrome c-proximal),GO:0009055; GO:0020037; GO:0005506; GO:0005743; GO:0005758; GO:0055114; GO:0006119; GO:0070469,electron carrier activity; heme binding; iron ion binding; mitochondrial inner membrane; mitochondrial intermembrane space; oxidation-reduction process; oxidative phosphorylation; respiratory chain,PF00034;,1.00E-63,CHOYP_CYC.3.5,1.00E-67,ruditapes_c140,8.00E-61,CX069346.p.cg.6,7,,CYC2_DROME,Drosophila melanogaster (Fruit fly),"mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; oxidation-reduction process [GO:0055114]; oxidative phosphorylation [GO:0006119]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]" comp123649_c0_seq1,756,37.6984,0.54209814,2140,6660,,1.00E-11,A8XZB0,"ATPase inhibitor mai-2, mitochondrial","ATPase inhibitor mai-2, mitochondrial",GO:0004857; GO:0005739; GO:0043086; GO:0045980,enzyme inhibitor activity; mitochondrion; negative regulation of catalytic activity; negative regulation of nucleotide metabolic process,PF04568;,,,2.00E-22,ruditapes_lrc37438,,,,,ATIF2_CAEBR,Caenorhabditis briggsae,heme biosynthetic process [GO:0006783]; negative regulation of ATPase activity [GO:0032780] comp123649_c0_seq2,732,37.5683,0.60398926,226,2782,,3.00E-12,Q03344,"ATPase inhibitor, mitochondrial (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)","ATPase inhibitor, mitochondrial (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)",GO:0051117; GO:0042030; GO:0043532; GO:0005516; GO:0009986; GO:0030218; GO:0006783; GO:0005739; GO:0001937; GO:0051346; GO:0045980; GO:0042803; GO:0051289,ATPase binding; ATPase inhibitor activity; angiostatin binding; calmodulin binding; cell surface; erythrocyte differentiation; heme biosynthetic process; mitochondrion; negative regulation of endothelial cell proliferation; negative regulation of hydrolase activity; negative regulation of nucleotide metabolic process; protein homodimerization activity; protein homotetramerization,PF04568;,,,,,,,,,ATIF1_RAT,Rattus norvegicus (Rat),erythrocyte differentiation [GO:0030218]; heme biosynthetic process [GO:0006783]; mitochondrial depolarization [GO:0051882]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of ATPase activity [GO:0032780]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of hydrolase activity [GO:0051346]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; reactive oxygen species metabolic process [GO:0072593]; regulation of ATP metabolic process [GO:1903578]; regulation of protein targeting to mitochondrion [GO:1903214] comp123650_c0_seq1,798,40.3509,0.97209729,10,149,,6.00E-49,Q969Q5,Ras-related protein Rab-24,Ras-related protein Rab-24,GO:0005525; GO:0005776; GO:0006914; GO:0005829; GO:0016020; GO:0005739; GO:0015031; GO:0007264,GTP binding; autophagic vacuole; autophagy; cytosol; membrane; mitochondrion; protein transport; small GTPase mediated signal transduction,PF00071;,,,2.00E-21,ruditapes2_c2690,,,,,RAB24_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp123665_c0_seq1,236,38.5593,0.23122366,1,8,,,,,,,,,2.00E-29,CHOYP_TFCP2.1.2,,,,,,,,, comp123665_c1_seq1,610,43.7705,0.45754731,21,64,,6.00E-27,Q4V860,Transcription factor CP2,Transcription factor CP2,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04516;,,,,,,,,,TFCP2_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123666_c1_seq1,1022,46.6732,0.47589954,81,21,,6.00E-75,Q9D994,WD repeat-containing protein 38,WD repeat-containing protein 38,,,PF00400;,5.00E-96,CHOYP_LOC100892811.2.2,,,,,,,WDR38_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244] comp123681_c0_seq2,1544,39.1192,0.75009962,25,77,,3.00E-12,Q96AE7,Tetratricopeptide repeat protein 17 (TPR repeat protein 17),Tetratricopeptide repeat protein 17 (TPR repeat protein 17),,,PF13181;,1.00E-61,CHOYP_PHUM_PHUM170150.1.1,2.00E-151,ruditapes_c17363,,,,,TTC17_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] comp123684_c0_seq1,537,42.6443,0.86178789,14,47,,2.00E-14,Q61704,Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH3_MOUSE,Mus musculus (Mouse),hyaluronan metabolic process [GO:0030212] comp123684_c2_seq1,410,38.7805,0.84944861,4,47,,9.00E-15,Q14624,Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4],Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4],GO:0006953; GO:0005737; GO:0004866; GO:0005576; GO:0030212; GO:0005886; GO:0034097; GO:0004867,acute-phase response; cytoplasm; endopeptidase inhibitor activity; extracellular region; hyaluronan metabolic process; plasma membrane; response to cytokine stimulus; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH4_HUMAN,Homo sapiens (Human),acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; platelet degranulation [GO:0002576]; response to cytokine [GO:0034097] comp123688_c0_seq1,350,45.1429,0.33750276,15,2,,2.00E-11,Q9BXP2,Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3),Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3),GO:0015377; GO:0016021; GO:0005886,cation:chloride symporter activity; integral to membrane; plasma membrane,PF00324;PF03522;,,,,,,,,,S12A9_HUMAN,Homo sapiens (Human), comp123688_c1_seq1,228,40.3509,0.32529035,7,0,,4.00E-13,Q91V14,Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (mKCC2) (Neuronal K-Cl cotransporter),Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (mKCC2) (Neuronal K-Cl cotransporter),GO:0030425; GO:0043198; GO:0016021; GO:0007612; GO:0035264; GO:0043025; GO:0005886; GO:0006813; GO:0015379; GO:0042493; GO:0007268; GO:0040040,dendrite; dendritic shaft; integral to membrane; learning; multicellular organism growth; neuronal cell body; plasma membrane; potassium ion transport; potassium:chloride symporter activity; response to drug; synaptic transmission; thermosensory behavior,PF00324;PF03522;,,,,,,,,,S12A5_MOUSE,Mus musculus (Mouse),cellular chloride ion homeostasis [GO:0030644]; chemical synaptic transmission [GO:0007268]; chloride transport [GO:0006821]; dendritic spine development [GO:0060996]; learning [GO:0007612]; multicellular organism growth [GO:0035264]; response to drug [GO:0042493]; thermosensory behavior [GO:0040040] comp123688_c2_seq2,1350,42.1481,0.43623968,35,38,,8.00E-74,P55013,Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter),Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter),GO:0015377; GO:0016021; GO:0006813; GO:0006814,cation:chloride symporter activity; integral to membrane; potassium ion transport; sodium ion transport,PF00324;PF08403;PF03522;,2.00E-46,CHOYP_S12A2.1.2,,,,,,,S12A2_SQUAC,Squalus acanthias (Spiny dogfish),potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] comp123691_c0_seq2,1395,41.7921,0.29635585,70,45,,2.00E-10,Q08378,Golgin subfamily A member 3 (Golgi complex-associated protein of 170 kDa) (GCP170) (Golgin-160),Golgin subfamily A member 3 (Golgi complex-associated protein of 170 kDa) (GCP170) (Golgin-160),GO:0032580; GO:0000139; GO:0017119; GO:0005793; GO:0006891; GO:0005634; GO:0005215,Golgi cisterna membrane; Golgi membrane; Golgi transport complex; endoplasmic reticulum-Golgi intermediate compartment; intra-Golgi vesicle-mediated transport; nucleus; transporter activity,,,,,,,,,,GOGA3_HUMAN,Homo sapiens (Human),intra-Golgi vesicle-mediated transport [GO:0006891]; spermatogenesis [GO:0007283] comp123693_c0_seq2,540,37.037,0.65338388,2,74,,5.00E-27,Q6Y288,"Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta-3-glycosyltransferase-like)","Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like)",GO:0005789; GO:0006004; GO:0016021; GO:0006486; GO:0016757,"endoplasmic reticulum membrane; fucose metabolic process; integral to membrane; protein glycosylation; transferase activity, transferring glycosyl groups",PF02434;,,,,,,,,,B3GLT_HUMAN,Homo sapiens (Human),fucose metabolic process [GO:0006004]; protein O-linked fucosylation [GO:0036066] comp123698_c0_seq2,319,52.6646,0.64073856,2,9,,,,,,,,,1.00E-14,CHOYP_HOW.5.5,5.00E-24,ruditapes2_c2864,,,,,,, comp123698_c3_seq1,577,38.1282,0.52899735,9,120,,4.00E-76,O01367,Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F),Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F),GO:0007475; GO:0008366; GO:0007155; GO:0005737; GO:0030718; GO:0008347; GO:0003730; GO:0008078; GO:0016203; GO:0007521; GO:0005634; GO:0007438; GO:0000381; GO:0008016; GO:0045214; GO:0007525; GO:0007284,"apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon ensheathment; cell adhesion; cytoplasm; germ-line stem cell maintenance; glial cell migration; mRNA 3'-UTR binding; mesodermal cell migration; muscle attachment; muscle cell fate determination; nucleus; oenocyte development; regulation of alternative mRNA splicing, via spliceosome; regulation of heart contraction; sarcomere organization; somatic muscle development; spermatogonial cell division",PF00013;PF16544;,7.00E-104,CHOYP_HOW.3.5,1.00E-67,ruditapes_c16249,,,,,HOW_DROME,Drosophila melanogaster (Fruit fly),"apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]" comp123702_c0_seq1,450,43.7778,0.55782588,3,0,,2.00E-14,P53599,MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of sensor kinase 2),MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of sensor kinase 2),GO:0005524; GO:0004709; GO:0000161; GO:0030036; GO:0005935; GO:0005934; GO:0005829; GO:0007234; GO:0046777,ATP binding; MAP kinase kinase kinase activity; MAPK cascade involved in osmosensory signaling pathway; actin cytoskeleton organization; cellular bud neck; cellular bud tip; cytosol; osmosensory signaling via phosphorelay pathway; protein autophosphorylation,PF00069;,,,,,,,,,SSK2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular hyperosmotic response [GO:0071474]; MAPK cascade involved in osmosensory signaling pathway [GO:0000161]; osmosensory signaling via phosphorelay pathway [GO:0007234]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403] comp123702_c0_seq2,760,46.7105,0.55713746,25,11,,1.00E-155,Q9ES74,Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7),Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7),GO:0005524; GO:0005737; GO:0046872; GO:0005815; GO:0005634; GO:0004674; GO:0000922,ATP binding; cytoplasm; metal ion binding; microtubule organizing center; nucleus; protein serine/threonine kinase activity; spindle pole,PF00069;,3.00E-142,CHOYP_LOC100371148.1.1,,,,,,,NEK7_MOUSE,Mus musculus (Mouse),positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468] comp123704_c0_seq1,484,41.1157,0.74023515,16,72,,2.00E-33,Q5F3W3,Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24),Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24),GO:0005524; GO:0004707; GO:0000165; GO:0007049,ATP binding; MAP kinase activity; MAPK cascade; cell cycle,PF00069;,5.00E-23,CHOYP_LOC100377214.1.1,,,,,,,MK06_CHICK,Gallus gallus (Chicken),cell cycle [GO:0007049] comp123705_c1_seq1,530,42.6415,0.37615246,17,7,,9.00E-73,Q6ZQ93,Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),GO:0016055; GO:0004197; GO:0090263; GO:0071108; GO:0004221; GO:0006511; GO:0004843,Wnt receptor signaling pathway; cysteine-type endopeptidase activity; positive regulation of canonical Wnt receptor signaling pathway; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,1.00E-69,CHOYP_UBP34.1.1,,,,,,,UBP34_MOUSE,Mus musculus (Mouse),"histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]" comp123709_c0_seq1,1213,39.5713,0.57160335,48,78,,9.00E-28,A4IF63,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_BOVIN,Bos taurus (Bovine),regulation of neuron apoptotic process [GO:0043523] comp123710_c0_seq1,673,43.685,0.54603628,53,33,,2.00E-36,Q66H07,Fibronectin type 3 and ankyrin repeat domains 1 protein,Fibronectin type 3 and ankyrin repeat domains 1 protein,GO:0005737; GO:0005634,cytoplasm; nucleus,PF12796;,9.00E-28,CHOYP_LOC100373728.1.1,,,,,,,FANK1_RAT,Rattus norvegicus (Rat), comp123711_c0_seq1,1315,38.8593,0.45079747,4,0,,1.00E-97,Q6P3Q6,Collagen type IV alpha-3-binding protein (Ceramide transfer protein),Collagen type IV alpha-3-binding protein (Ceramide transfer protein),GO:0005794; GO:0005783; GO:0006869; GO:0005543,Golgi apparatus; endoplasmic reticulum; lipid transport; phospholipid binding,PF00169;PF01852;,,,,,,,,,C43BP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),lipid transport [GO:0006869] comp123711_c0_seq3,1115,38.4753,0.49512019,0,0,,,,,,,,,4.00E-79,CHOYP_C43BP.1.1,,,,,,,,, comp123714_c1_seq1,1460,43.7671,0.4338575,3,0,,2.00E-69,Q03164,Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],GO:0003680; GO:0006306; GO:0071339; GO:0009952; GO:0006915; GO:0003682; GO:0035162; GO:0080182; GO:0043984; GO:0070577; GO:0042800; GO:0008285; GO:2001040; GO:0045944; GO:0032411; GO:0006461; GO:0042803; GO:0051569; GO:0003700; GO:0006366; GO:0044212; GO:0045322; GO:0008270,AT DNA binding; DNA methylation; MLL1 complex; anterior/posterior pattern specification; apoptotic process; chromatin binding; embryonic hemopoiesis; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); negative regulation of cell proliferation; positive regulation of cellular response to drug; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transporter activity; protein complex assembly; protein homodimerization activity; regulation of histone H3-K4 methylation; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; unmethylated CpG binding; zinc ion binding,PF05965;PF05964;PF00628;PF00856;PF02008;,,,,,,,,,MLL1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription from RNA polymerase II promoter [GO:0006366]; visual learning [GO:0008542]" comp123714_c1_seq2,1648,43.932,0.48322362,34,10,,8.00E-119,Q03164,Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],GO:0003680; GO:0006306; GO:0071339; GO:0009952; GO:0006915; GO:0003682; GO:0035162; GO:0080182; GO:0043984; GO:0070577; GO:0042800; GO:0008285; GO:2001040; GO:0045944; GO:0032411; GO:0006461; GO:0042803; GO:0051569; GO:0003700; GO:0006366; GO:0044212; GO:0045322; GO:0008270,AT DNA binding; DNA methylation; MLL1 complex; anterior/posterior pattern specification; apoptotic process; chromatin binding; embryonic hemopoiesis; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); negative regulation of cell proliferation; positive regulation of cellular response to drug; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transporter activity; protein complex assembly; protein homodimerization activity; regulation of histone H3-K4 methylation; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; unmethylated CpG binding; zinc ion binding,PF05965;PF05964;PF00628;PF00856;PF02008;,1.00E-88,CHOYP_MLL.1.1,,,,,,,MLL1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription from RNA polymerase II promoter [GO:0006366]; visual learning [GO:0008542]" comp123717_c0_seq1,968,41.1157,0.31822694,45,31,,5.00E-72,P79987,Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1),Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1),GO:0003682; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07569;PF09453;PF00400;,,,,,,,,,HIRA_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp123718_c0_seq1,649,33.7442,0.38370811,218,603,,5.00E-37,Q3SZ85,Putative peptidyl-tRNA hydrolase PTRHD1 (EC 3.1.1.29) (Peptidyl-tRNA hydrolase domain-containing protein 1),Putative peptidyl-tRNA hydrolase PTRHD1 (EC 3.1.1.29) (Peptidyl-tRNA hydrolase domain-containing protein 1),GO:0004045; GO:0035335; GO:0004725,aminoacyl-tRNA hydrolase activity; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF01981;,4.00E-32,CHOYP_BRAFLDRAFT_274939.1.1,,,,,,,PTRD1_BOVIN,Bos taurus (Bovine), comp123719_c0_seq4,922,45.5531,0.56530781,19,10,,,,,,,,,2.00E-13,CHOYP_LOC100377268.1.1,,,,,,,,, comp123722_c0_seq1,911,48.4083,0.69627023,43,33,,2.00E-07,Q9WVC7,A-kinase anchor protein 6 (AKAP-6) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP),A-kinase anchor protein 6 (AKAP-6) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP),GO:0030315; GO:0008179; GO:0005901; GO:0034629; GO:0071345; GO:0071872; GO:0014704; GO:0014701; GO:0030818; GO:0005640; GO:0048471; GO:0051533; GO:2000481; GO:0070886; GO:0061051; GO:0032514; GO:0051281; GO:0060316; GO:0043495; GO:0043234; GO:0032947; GO:0034237; GO:0051721; GO:0086004; GO:0010738; GO:1901897; GO:0010880,T-tubule; adenylate cyclase binding; caveola; cellular protein complex localization; cellular response to cytokine stimulus; cellular response to epinephrine stimulus; intercalated disc; junctional sarcoplasmic reticulum membrane; negative regulation of cAMP biosynthetic process; nuclear outer membrane; perinuclear region of cytoplasm; positive regulation of NFAT protein import into nucleus; positive regulation of cAMP-dependent protein kinase activity; positive regulation of calcineurin-NFAT signaling cascade; positive regulation of cell growth involved in cardiac muscle cell development; positive regulation of protein phosphatase type 2B activity; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of ryanodine-sensitive calcium-release channel activity; protein anchor; protein complex; protein complex scaffold; protein kinase A regulatory subunit binding; protein phosphatase 2A binding; regulation of cardiac muscle cell contraction; regulation of protein kinase A signaling cascade; regulation of relaxation of cardiac muscle; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,PF00435;,,,,,,,,,AKAP6_RAT,Rattus norvegicus (Rat),cellular protein complex localization [GO:0034629]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epinephrine stimulus [GO:0071872]; negative regulation of cAMP biosynthetic process [GO:0030818]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell growth [GO:0030307]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of protein phosphatase type 2B activity [GO:0032514]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of protein kinase A signaling [GO:0010738]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880] comp12372_c0_seq1,209,45.4545,0.47728365,3,0,,6.00E-23,Q5F452,Myotubularin-related protein 8 (EC 3.1.3.-),Myotubularin-related protein 8 (EC 3.1.3.-),GO:0005635; GO:0035335; GO:0004725,nuclear envelope; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF06602;,,,,,,,,,MTMR8_CHICK,Gallus gallus (Chicken),phosphatidylinositol dephosphorylation [GO:0046856]; regulation of autophagy [GO:0010506] comp123734_c1_seq1,1066,41.3696,0.38084774,52,156,,4.00E-37,Q8BWR4,Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP40_MOUSE,Mus musculus (Mouse),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp123737_c1_seq1,1149,47.8677,0.44333699,80,0,,2.00E-09,P48479,G2-specific protein kinase nim-1 (EC 2.7.11.1),G2-specific protein kinase nim-1 (EC 2.7.11.1),GO:0005524; GO:0051301; GO:0007067; GO:0005634; GO:0050921; GO:0004674,ATP binding; cell division; mitosis; nucleus; positive regulation of chemotaxis; protein serine/threonine kinase activity,PF00069;,,,,,,,,,NIM1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),mitotic spindle assembly [GO:0090307]; negative regulation of septation initiation signaling [GO:0031030]; positive regulation of chemotaxis [GO:0050921]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic chromosome condensation [GO:1903380]; septation initiation signaling [GO:0031028] comp123737_c3_seq1,1249,45.0761,0.4112261,80,4,,2.00E-133,Q3UGM2,Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10),Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10),GO:0005524; GO:0046872; GO:0018108; GO:0004674; GO:0004713,ATP binding; metal ion binding; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;,9.00E-69,CHOYP_BRAFLDRAFT_76429.1.1,,,,,,,NEK10_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; protein phosphorylation [GO:0006468] comp123751_c0_seq1,1050,35.7143,0.97062137,26,244,,9.00E-10,Q8R4G9,Neuronal acetylcholine receptor subunit alpha-3,Neuronal acetylcholine receptor subunit alpha-3,GO:0015464; GO:0004889; GO:0005892; GO:0007171; GO:0035095; GO:0030054; GO:0007626; GO:0045211; GO:0014056; GO:0048814; GO:0060079; GO:0006940; GO:0060084; GO:0007271,"acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; activation of transmembrane receptor protein tyrosine kinase activity; behavioral response to nicotine; cell junction; locomotory behavior; postsynaptic membrane; regulation of acetylcholine secretion, neurotransmission; regulation of dendrite morphogenesis; regulation of excitatory postsynaptic membrane potential; regulation of smooth muscle contraction; synaptic transmission involved in micturition; synaptic transmission, cholinergic",PF02931;PF02932;,3.00E-16,CHOYP_SMP_037960.1.1,,,,,,,ACHA3_MOUSE,Mus musculus (Mouse),"activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; excitatory postsynaptic potential [GO:0060079]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; regulation of smooth muscle contraction [GO:0006940]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission involved in micturition [GO:0060084]" comp123752_c1_seq1,929,45.7481,0.93240461,17,123,,5.00E-13,Q9DB72,BTB/POZ domain-containing protein 17 (Galectin-3-binding protein-like),BTB/POZ domain-containing protein 17 (Galectin-3-binding protein-like),GO:0005576,extracellular region,PF07707;PF00651;,3.00E-22,CHOYP_LOC592989.1.1,,,,,,,BTBDH_MOUSE,Mus musculus (Mouse), comp123753_c0_seq2,603,44.6103,0.63692039,4,12,,3.00E-63,Q7Z3U7,Protein MON2 homolog (Protein SF21),Protein MON2 homolog (Protein SF21),GO:0005086; GO:0006895; GO:0030036; GO:0015031; GO:0005802,ARF guanyl-nucleotide exchange factor activity; Golgi to endosome transport; actin cytoskeleton organization; protein transport; trans-Golgi network,PF16213;PF09324;PF16206;PF12783;,,,,,,,,,MON2_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] comp123756_c0_seq1,509,34.5776,0.53243061,39,42,,4.00E-07,A1L1L1,Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein),Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein),GO:0003677; GO:0051301; GO:0007059; GO:0000777; GO:0000776; GO:0051382; GO:0007067; GO:0000278; GO:0005634,DNA binding; cell division; chromosome segregation; condensed chromosome kinetochore; kinetochore; kinetochore assembly; mitosis; mitotic cell cycle; nucleus,PF15510;,,,,,,,,,CENPW_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; chromosome organization [GO:0051276]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067] comp123757_c0_seq1,445,33.4831,0.69552008,69,206,,,,,,,,,,,2.00E-11,ruditapes_lrc24204,,,,,,, comp123769_c0_seq1,351,36.1823,0.61202683,14399,43216,,,,,,,,,,,3.00E-59,ruditapes_lrc33899,,,,,,, comp123769_c1_seq1,755,42.1192,0.48168291,68134,184064,,1.00E-82,Q5R931,60S ribosomal protein L10,60S ribosomal protein L10,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00252;,1.00E-84,CHOYP_RL10.3.3,2.00E-98,ruditapes_lrc30594,,,,,RL10_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),translation [GO:0006412] comp123770_c0_seq1,936,45.0855,0.54962274,70955,372496,,3.00E-117,O57592,60S ribosomal protein L7a (Surfeit locus protein 3),60S ribosomal protein L7a (Surfeit locus protein 3),GO:0005840; GO:0042254,ribosome; ribosome biogenesis,PF01248;,9.00E-137,CHOYP_RL7A.4.6,0,ruditapes_lrc34182,,,,,RL7A_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412] comp123774_c0_seq1,1576,45.2411,0.51077549,295208,17919,,0,P06603,Tubulin alpha-1 chain,Tubulin alpha-1 chain,GO:0005525; GO:0003924; GO:0019730; GO:0000235; GO:0005813; GO:0007094; GO:0007052; GO:0051258; GO:0005200,GTP binding; GTPase activity; antimicrobial humoral response; astral microtubule; centrosome; mitotic spindle assembly checkpoint; mitotic spindle organization; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_RABGAP1.1.1,0,ruditapes2_c97,0,AJ431728.p.cg.6,6,male gonad,TBA1_DROME,Drosophila melanogaster (Fruit fly),antimicrobial humoral response [GO:0019730]; mitotic spindle assembly checkpoint [GO:0007094]; mitotic spindle organization [GO:0007052] comp123777_c0_seq1,1450,41.1034,0.55735213,24,39,,2.00E-135,B4JTV9,Leucine-rich repeat protein soc-2 homolog (Protein Sur-8 homolog) (Protein soc-2 homolog),Leucine-rich repeat protein soc-2 homolog (Protein Sur-8 homolog) (Protein soc-2 homolog),GO:0046579; GO:0000164,positive regulation of Ras protein signal transduction; protein phosphatase type 1 complex,PF00560;PF13855;,3.00E-95,CHOYP_LOC100863920.1.1,,,,,,,SUR8_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi), comp123777_c0_seq2,954,40.9853,0.5311463,0,0,,8.00E-06,Q7XA40,Putative disease resistance protein RGA3 (Blight resistance protein B149) (RGA1-blb),Putative disease resistance protein RGA3 (Blight resistance protein B149) (RGA1-blb),GO:0043531; GO:0005524; GO:0006952,ADP binding; ATP binding; defense response,PF13855;PF00931;,,,,,,,,,RGA3_SOLBU,Solanum bulbocastanum (Wild potato),defense response [GO:0006952] comp123780_c1_seq1,2346,36.7434,0.45484504,62591,206927,,5.00E-75,Q2YGT9,60S ribosomal protein L6,60S ribosomal protein L6,GO:0022625; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; structural constituent of ribosome; translation,PF01159;PF03868;,7.00E-86,CHOYP_BRAFLDRAFT_114734.2.8,8.00E-153,ruditapes_lrc32261,,,,,RL6_PIG,Sus scrofa (Pig),cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] comp123785_c0_seq1,303,39.604,0.67631437,52366,63601,,9.00E-45,Q90YT6,60S ribosomal protein L32,60S ribosomal protein L32,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01655;,3.00E-54,CHOYP_BRAFLDRAFT_114866.5.5,3.00E-72,ruditapes_lrc34654,,,,,RL32_ICTPU,Ictalurus punctatus (Channel catfish) (Silurus punctatus),translation [GO:0006412] comp123785_c1_seq1,265,43.0189,0.65578746,39121,46224,,5.00E-12,P34040,60S ribosomal protein L32,60S ribosomal protein L32,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01655;,,,,,,,,,RL32_TRIHA,Trichoderma harzianum (Hypocrea lixii),translation [GO:0006412] comp123801_c0_seq1,766,46.2141,0.76013557,30911,205093,,3.00E-74,P42577,Soma ferritin (EC 1.16.3.1),Soma ferritin (EC 1.16.3.1),GO:0006879; GO:0005737; GO:0008199; GO:0004322; GO:0006826,cellular iron ion homeostasis; cytoplasm; ferric iron binding; ferroxidase activity; iron ion transport,PF00210;,1.00E-82,CHOYP_FRIS.9.11,9.00E-140,ruditapes_c3824,,,,,FRIS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] comp123805_c0_seq1,1432,41.2709,0.60959123,81043,285031,,0,P49165,60S ribosomal protein L4 (L1),60S ribosomal protein L4 (L1),GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF14374;PF00573;,4.00E-169,CHOYP_RL4B.1.1,0,ruditapes_c1609,,,,,RL4_URECA,Urechis caupo (Innkeeper worm) (Spoonworm),translation [GO:0006412] comp123806_c0_seq1,570,45.2632,0.58759261,9,14,,8.00E-14,Q8NBI5,Solute carrier family 43 member 3 (Protein FOAP-13),Solute carrier family 43 member 3 (Protein FOAP-13),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S43A3_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp123809_c0_seq2,1033,38.2381,0.66993273,0,0,,1.00E-170,Q6TNP8,Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A),Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A),GO:0005768; GO:0010008; GO:0015031; GO:0030904; GO:0007034; GO:0031982,endosome; endosome membrane; protein transport; retromer complex; vacuolar transport; vesicle,PF03643;,,,4.00E-44,ruditapes_c19197,,,,,VP26A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]" comp123809_c0_seq4,1034,39.265,0.66007715,8,27,,0,Q6DH23,Vacuolar protein sorting-associated protein 26B-like (Vesicle protein sorting 26B-like),Vacuolar protein sorting-associated protein 26B-like (Vesicle protein sorting 26B-like),GO:0005737; GO:0015031; GO:0030904; GO:0007034,cytoplasm; protein transport; retromer complex; vacuolar transport,PF03643;,0,CHOYP_ISCW_ISCW018536.1.1,2.00E-156,ruditapes_c25855,,,,,V26BL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]" comp123811_c0_seq1,859,44.4703,0.5930061,47831,166998,,3.00E-67,Q5R9I9,Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC),Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC),GO:0003677; GO:0005737; GO:0005634; GO:0015031; GO:0006351,"DNA binding; cytoplasm; nucleus; protein transport; transcription, DNA-dependent",PF01849;,2.00E-107,CHOYP_NACA.8.9,7.00E-167,ruditapes2_c3518,,,,,NACA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"protein transport [GO:0015031]; transcription, DNA-templated [GO:0006351]" comp123814_c0_seq1,954,36.0587,0.65198911,377,555,,2.00E-26,Q8C6U2,PQ-loop repeat-containing protein 3,PQ-loop repeat-containing protein 3,GO:0016021,integral to membrane,PF04193;,,,,,,,,,PQLC3_MOUSE,Mus musculus (Mouse),dolichol-linked oligosaccharide biosynthetic process [GO:0006488] comp123825_c1_seq4,839,40.5244,0.84293694,0,0,,9.00E-24,Q9NXR1,Nuclear distribution protein nudE homolog 1 (NudE),Nuclear distribution protein nudE homolog 1 (NudE),GO:0000086; GO:0051301; GO:0051298; GO:0021987; GO:0032154; GO:0000777; GO:0005829; GO:0051303; GO:0000132; GO:0000776; GO:0005874; GO:0008017; GO:0007020; GO:0007067; GO:0007405; GO:0001764; GO:0031616; GO:0047496,G2/M transition of mitotic cell cycle; cell division; centrosome duplication; cerebral cortex development; cleavage furrow; condensed chromosome kinetochore; cytosol; establishment of chromosome localization; establishment of mitotic spindle orientation; kinetochore; microtubule; microtubule binding; microtubule nucleation; mitosis; neuroblast proliferation; neuron migration; spindle pole centrosome; vesicle transport along microtubule,PF04880;,,,,,,,,,NDE1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cell migration [GO:0016477]; centrosome duplication [GO:0051298]; centrosome localization [GO:0051642]; cerebral cortex development [GO:0021987]; chromosome segregation [GO:0007059]; establishment of chromosome localization [GO:0051303]; establishment of mitotic spindle orientation [GO:0000132]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule nucleation [GO:0007020]; mitotic centrosome separation [GO:0007100]; neuroblast proliferation [GO:0007405]; neuron migration [GO:0001764]; sister chromatid cohesion [GO:0007062]; vesicle transport along microtubule [GO:0047496] comp123829_c0_seq1,1649,34.5058,0.51284302,32,14,,8.00E-16,Q3UN21,Sodium-dependent glucose transporter 1C,Sodium-dependent glucose transporter 1C (Major facilitator superfamily domain-containing protein 4B3),GO:0016324; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,,,,,,,,,,NAGTC_MOUSE,Mus musculus (Mouse),carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp123833_c0_seq1,928,43.6422,0.43266547,51,7,,8.00E-104,A1A5F2,HEAT repeat-containing protein 5B,HEAT repeat-containing protein 5B,,,,3.00E-111,CHOYP_HTR5B.1.1,,,,,,,HTR5B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp123835_c0_seq1,633,41.7062,0.65874097,138,1028,,2.00E-21,Q8R034,Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13),Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13),GO:0005680; GO:0051301; GO:0007067; GO:0070979,anaphase-promoting complex; cell division; mitosis; protein K11-linked ubiquitination,PF05839;,1.00E-31,CHOYP_DPSE_GA30464.1.1,1.00E-48,ruditapes_c19318,,,,,APC13_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979] comp123844_c0_seq1,360,40.2778,0.61815545,18,0,,8.00E-08,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,1.00E-15,CHOYP_BRAFLDRAFT_106560.1.14,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp123846_c0_seq1,721,39.8058,0.53062326,7,11,,2.00E-54,P07686,Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A],Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A],GO:0001669; GO:0043615; GO:0004563; GO:0005975; GO:0008219; GO:0006874; GO:0044267; GO:0030207; GO:0006689; GO:0006687; GO:0030214; GO:0042340; GO:0019915; GO:0007626; GO:0043202; GO:0007040; GO:0008049; GO:0016020; GO:0042552; GO:0050885; GO:0009313; GO:0048477; GO:0007341; GO:0008654; GO:0045944; GO:0046982; GO:0042803; GO:0008360; GO:0007605; GO:0001501,acrosomal vesicle; astrocyte cell migration; beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; cell death; cellular calcium ion homeostasis; cellular protein metabolic process; chondroitin sulfate catabolic process; ganglioside catabolic process; glycosphingolipid metabolic process; hyaluronan catabolic process; keratan sulfate catabolic process; lipid storage; locomotory behavior; lysosomal lumen; lysosome organization; male courtship behavior; membrane; myelination; neuromuscular process controlling balance; oligosaccharide catabolic process; oogenesis; penetration of zona pellucida; phospholipid biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; protein homodimerization activity; regulation of cell shape; sensory perception of sound; skeletal system development,PF00728;PF14845;,2.00E-61,CHOYP_LOC100708717.1.1,9.00E-51,ruditapes_c8084,,,,,HEXB_HUMAN,Homo sapiens (Human),astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501] comp123846_c0_seq2,743,39.3001,0.42218831,11,34,,8.00E-18,Q54K55,Beta-hexosaminidase subunit B1 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit B1) (N-acetyl-beta-glucosaminidase subunit B1),Beta-hexosaminidase subunit B1 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit B1) (N-acetyl-beta-glucosaminidase subunit B1),GO:0004563; GO:0005975; GO:0005764,beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; lysosome,PF00728;PF14845;,4.00E-26,CHOYP_HEXB.1.1,,,,,,,HEXB1_DICDI,Dictyostelium discoideum (Slime mold),carbohydrate metabolic process [GO:0005975] comp123850_c0_seq1,636,42.6101,0.28033956,36,69,,1.00E-15,Q8N128,Protein FAM177A1,Protein FAM177A1,,,PF14774;,,,,,,,,,F177A_HUMAN,Homo sapiens (Human), comp123851_c0_seq1,1856,39.8168,0.45606854,107,39,,0,Q96L92,Sorting nexin-27,Sorting nexin-27,GO:0005829; GO:0005769; GO:0031901; GO:0008333; GO:0001770; GO:0001772; GO:0006886; GO:0005634; GO:0032266; GO:1990126; GO:0007165,"cytosol; early endosome; early endosome membrane; endosome to lysosome transport; establishment of natural killer cell polarity; immunological synapse; intracellular protein transport; nucleus; phosphatidylinositol-3-phosphate binding; retrograde transport, endosome to plasma membrane; signal transduction",PF00595;PF00787;PF00788;,0,CHOYP_LOC100904232.1.1,,,,,,,SNX27_HUMAN,Homo sapiens (Human),"endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; establishment of natural killer cell polarity [GO:0001770]; intracellular protein transport [GO:0006886]; response to drug [GO:0042493]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]" comp123857_c0_seq1,1341,39.0007,0.866951,0,0,,9.00E-08,O88454,Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK),Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK),GO:0016021; GO:0005267; GO:0005244,integral to membrane; potassium channel activity; voltage-gated ion channel activity,PF07885;,1.00E-41,CHOYP_LOC100120322.3.3,,,,,,,KCNK4_MOUSE,Mus musculus (Mouse),cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322] comp123857_c0_seq2,1463,39.2344,0.89080396,0,29,,8.00E-42,O17185,Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38),Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38),GO:0005887; GO:0036195; GO:0005267; GO:0006937; GO:0055120,integral to plasma membrane; muscle cell projection membrane; potassium channel activity; regulation of muscle contraction; striated muscle dense body,PF07885;,,,,,,,,,SUP9_CAEEL,Caenorhabditis elegans,potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322] comp123857_c1_seq1,234,44.4444,0.97918455,2,18,,1.00E-25,Q9JL58,Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3),Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3),GO:0016021; GO:0005267; GO:0005244,integral to membrane; potassium channel activity; voltage-gated ion channel activity,PF07885;,,,,,,,,,KCNK9_CAVPO,Cavia porcellus (Guinea pig), comp123858_c0_seq2,773,40.4916,0.74361027,28,5,,4.00E-36,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp123859_c0_seq1,1004,45.4183,0.59950414,25,116,,8.00E-35,Q7PQ25,Coiled-coil domain-containing protein AGAP005037,Coiled-coil domain-containing protein AGAP005037,,,PF03915;,1.00E-21,CHOYP_LOC100883165.2.2,,,,,,,CCDCX_ANOGA,Anopheles gambiae (African malaria mosquito), comp123860_c0_seq2,1938,41.9505,0.76448808,52,22,,5.00E-148,Q9WTR6,Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT),Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT),GO:0015171; GO:0016021; GO:0070527; GO:0009636,amino acid transmembrane transporter activity; integral to membrane; platelet aggregation; response to toxic substance,PF13520;,4.00E-164,CHOYP_LOC100904518.1.1,,,,,,,XCT_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; lens fiber cell differentiation [GO:0070306]; L-glutamate transmembrane transport [GO:0089711]; platelet aggregation [GO:0070527]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636] comp123863_c0_seq1,1111,37.7138,0.51211242,68,191,,5.00E-110,Q5RCS8,V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D),V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D),GO:0042626; GO:0005813; GO:0005929; GO:0042384; GO:0061512; GO:0015992; GO:0016471,"ATPase activity, coupled to transmembrane movement of substances; centrosome; cilium; cilium assembly; protein localization to cilium; proton transport; vacuolar proton-transporting V-type ATPase complex",PF01813;,2.00E-132,CHOYP_VATD.2.2,,,,,,,VATD_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cilium assembly [GO:0042384]; protein localization to cilium [GO:0061512]; proton transport [GO:0015992] comp123865_c0_seq1,1686,38.0783,0.69543137,924,77,,5.00E-31,P58929,Glucocorticoid modulatory element-binding protein 2 (GMEB-2),Glucocorticoid modulatory element-binding protein 2 (GMEB-2),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0006355; GO:0003713; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent",PF01342;,1.00E-11,CHOYP_BRAFLDRAFT_119363.1.1,,,,,,,GMEB2_MOUSE,Mus musculus (Mouse),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp123873_c0_seq1,1311,43.402,0.64160539,46,86,,1.00E-30,Q5FWN8,DnaJ homolog subfamily B member 6-A,DnaJ homolog subfamily B member 6-A,GO:0005634; GO:0048471,nucleus; perinuclear region of cytoplasm,PF00226;,,,,,,,,,DNJ6A_XENLA,Xenopus laevis (African clawed frog), comp123873_c0_seq2,1260,43.1746,0.64005802,2,11,,6.00E-31,Q8WWF6,DnaJ homolog subfamily B member 3,DnaJ homolog subfamily B member 3,,,PF00226;,1.00E-35,CHOYP_DNAJB6B.2.2,,,,,,,DNJB3_HUMAN,Homo sapiens (Human), comp123874_c0_seq2,859,37.0198,0.58856763,5,31,,6.00E-66,Q9CY94,DNA replication complex GINS protein PSF3 (GINS complex subunit 3),DNA replication complex GINS protein PSF3 (GINS complex subunit 3),GO:0006260; GO:0005634,DNA replication; nucleus,PF05916;,7.00E-68,CHOYP_GINS3.1.1,,,2.00E-69,FP005816.p.cg.6,8,,PSF3_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260] comp123874_c0_seq3,479,37.3695,1.03896557,0,3,,,,,,,,,4.00E-30,CHOYP_GINS3.1.1,,,,,,,,, comp123875_c0_seq2,950,41.6842,0.44430074,0,0,,6.00E-32,Q9PBI4,Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II),Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II),GO:0006750; GO:0004416; GO:0008270,glutathione biosynthetic process; hydroxyacylglutathione hydrolase activity; zinc ion binding,PF16123;PF00753;,,,,,,,,,GLO2_XYLFA,Xylella fastidiosa (strain 9a5c),methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] comp123875_c0_seq4,1001,41.8581,0.41663243,2,0,,2.00E-69,Q8N490,Probable hydrolase PNKD (EC 3.-.-.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Trans-activated by hepatitis C virus core protein 2),Probable hydrolase PNKD (EC 3.-.-.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Trans-activated by hepatitis C virus core protein 2),GO:0006750; GO:0004416; GO:0016020; GO:0005739; GO:0005634; GO:0008270,glutathione biosynthetic process; hydroxyacylglutathione hydrolase activity; membrane; mitochondrion; nucleus; zinc ion binding,PF16123;PF00753;,,,,,,,,,PNKD_HUMAN,Homo sapiens (Human),"methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; negative regulation of neurotransmitter secretion [GO:0046929]; neuromuscular process controlling posture [GO:0050884]; regulation of dopamine metabolic process [GO:0042053]; regulation of synaptic transmission, dopaminergic [GO:0032225]" comp123896_c1_seq1,360,40,0.43190762,8,11,,3.00E-11,Q54F23,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog),,,,1.00E-23,CHOYP_HEATR7A.1.1,,,,,,,HTR7A_DICDI,Dictyostelium discoideum (Slime mold), comp123896_c2_seq1,456,43.4211,0.42120018,22,16,,4.00E-20,Q8NDA8,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),,,PF02985;,,,,,,,,,HTR7A_HUMAN,Homo sapiens (Human), comp123898_c1_seq1,316,49.0506,0.81282865,16,17,,1.00E-12,Q8VYA1,Probable poly(ADP-ribose) glycohydrolase 2 (EC 3.2.1.143),Probable poly(ADP-ribose) glycohydrolase 2 (EC 3.2.1.143),GO:0005975; GO:0050832; GO:0004649,carbohydrate metabolic process; defense response to fungus; poly(ADP-ribose) glycohydrolase activity,PF05028;,,,,,,,,,PARG2_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; defense response to fungus [GO:0050832] comp123906_c0_seq1,1121,44.6922,0.51851893,63,58,,2.00E-16,P59759,MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B),MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B),GO:0003779; GO:0048514; GO:0048738; GO:0005737; GO:0048568; GO:0010467; GO:0003007; GO:0001701; GO:0001889; GO:0007517; GO:0003676; GO:0005634; GO:0045844; GO:0045944; GO:0003700; GO:0051145; GO:0003713; GO:0006351,"actin binding; blood vessel morphogenesis; cardiac muscle tissue development; cytoplasm; embryonic organ development; gene expression; heart morphogenesis; in utero embryonic development; liver development; muscle organ development; nucleic acid binding; nucleus; positive regulation of striated muscle tissue development; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; smooth muscle cell differentiation; transcription coactivator activity; transcription, DNA-dependent",PF02755;PF02037;,5.00E-27,CHOYP_MKL2.1.1,,,,,,,MKL2_MOUSE,Mus musculus (Mouse),"actin cytoskeleton organization [GO:0030036]; blood vessel morphogenesis [GO:0048514]; cardiac muscle tissue development [GO:0048738]; embryonic organ development [GO:0048568]; forebrain development [GO:0030900]; gene expression [GO:0010467]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; muscle organ development [GO:0007517]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; positive regulation of striated muscle tissue development [GO:0045844]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; smooth muscle cell differentiation [GO:0051145]" comp123907_c0_seq1,618,36.8932,0.51704111,36,94,,6.00E-25,Q9Z2L6,"Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)","Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)",GO:0003993; GO:0034417; GO:0016311; GO:0005788; GO:0052826; GO:0005886,acid phosphatase activity; bisphosphoglycerate 3-phosphatase activity; dephosphorylation; endoplasmic reticulum lumen; inositol hexakisphosphate 2-phosphatase activity; plasma membrane,PF00328;,,,,,,,,,MINP1_MOUSE,Mus musculus (Mouse), comp123907_c2_seq1,933,36.7631,0.3181636,40,198,,2.00E-14,Q54ND5,"Multiple inositol polyphosphate phosphatase 1 (Ddmipp1) (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)","Multiple inositol polyphosphate phosphatase 1 (Ddmipp1) (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)",GO:0003993; GO:0034417; GO:0005829; GO:0006007; GO:0052826; GO:0016021,acid phosphatase activity; bisphosphoglycerate 3-phosphatase activity; cytosol; glucose catabolic process; inositol hexakisphosphate 2-phosphatase activity; integral to membrane,PF00328;,,,,,,,,,MINP1_DICDI,Dictyostelium discoideum (Slime mold),glucose catabolic process [GO:0006007] comp123914_c0_seq1,775,40.9032,0.61788721,7,12,,2.00E-07,Q9VCU9,Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-),Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-),GO:0005524; GO:0016442; GO:0016443; GO:0005737; GO:0048813; GO:0003725; GO:0033227; GO:0042078; GO:0030727; GO:0007294; GO:0004386; GO:0046872; GO:0045448; GO:0007279; GO:0070883; GO:0031054; GO:0030422; GO:0007367; GO:0035087; GO:0003727,"ATP binding; RISC complex; bidentate ribonuclease III activity; cytoplasm; dendrite morphogenesis; double-stranded RNA binding; dsRNA transport; germ-line stem cell division; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; helicase activity; metal ion binding; mitotic cell cycle, embryonic; pole cell formation; pre-miRNA binding; pre-miRNA processing; production of siRNA involved in RNA interference; segment polarity determination; siRNA loading onto RISC involved in RNA interference; single-stranded RNA binding",PF03368;PF00271;PF02170;PF00636;,9.00E-16,CHOYP_IFIH1.9.14,,,,,,,DCR1_DROME,Drosophila melanogaster (Fruit fly),"apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line stem cell division [GO:0042078]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; response to starvation [GO:0042594]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]" comp123914_c0_seq2,1522,41.9185,0.58958268,50,58,,5.00E-52,Q99J87,Probable ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor Lgp2) (RLR),Probable ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor Lgp2) (RLR),GO:0005524; GO:0003677; GO:0005737; GO:0051607; GO:0003725; GO:0004386; GO:0045087; GO:0039534; GO:0039536; GO:0045824; GO:0032480; GO:1900245; GO:1900246; GO:0032481; GO:0009615; GO:0003727; GO:0008270,ATP binding; DNA binding; cytoplasm; defense response to virus; double-stranded RNA binding; helicase activity; innate immune response; negative regulation of MDA-5 signaling pathway; negative regulation of RIG-I signaling pathway; negative regulation of innate immune response; negative regulation of type I interferon production; positive regulation of MDA-5 signaling pathway; positive regulation of RIG-I signaling pathway; positive regulation of type I interferon production; response to virus; single-stranded RNA binding; zinc ion binding,PF00271;PF04851;PF11648;,2.00E-15,CHOYP_IFIH1.9.14,,,,,,,DHX58_MOUSE,Mus musculus (Mouse),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of innate immune response [GO:0045088]; response to virus [GO:0009615] comp123918_c0_seq1,380,46.8421,0.43339532,18,7,,3.00E-31,Q6ZPY2,Protein SMG5 (EST1-like protein B) (SMG-5 homolog),Protein SMG5 (EST1-like protein B) (SMG-5 homolog),GO:0005737; GO:0000184; GO:0005634; GO:0051721; GO:0035303,"cytoplasm; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; protein phosphatase 2A binding; regulation of dephosphorylation",PF10374;PF10373;PF13638;,3.00E-30,CHOYP_SMG5.1.1,,,,,,,SMG5_MOUSE,Mus musculus (Mouse),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]" comp123931_c0_seq1,617,35.4943,0.50289463,19,82,,4.00E-28,Q9CQ92,Mitochondrial fission 1 protein (FIS1 homolog) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11),Mitochondrial fission 1 protein (FIS1 homolog) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11),GO:0035584; GO:0007204; GO:0051561; GO:0031307; GO:0005779; GO:0043653; GO:0008053; GO:0000422; GO:0070584; GO:0016559; GO:0043280; GO:2001244; GO:0090141; GO:0090314; GO:0043234; GO:0051260; GO:0006626; GO:0032471; GO:0001836,calcium-mediated signaling using intracellular calcium source; elevation of cytosolic calcium ion concentration; elevation of mitochondrial calcium ion concentration; integral to mitochondrial outer membrane; integral to peroxisomal membrane; mitochondrial fragmentation involved in apoptotic process; mitochondrial fusion; mitochondrion degradation; mitochondrion morphogenesis; peroxisome fission; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of mitochondrial fission; positive regulation of protein targeting to membrane; protein complex; protein homooligomerization; protein targeting to mitochondrion; reduction of endoplasmic reticulum calcium ion concentration; release of cytochrome c from mitochondria,PF14853;PF14852;,8.00E-15,CHOYP_LOC100367718.1.1,,,,,,,FIS1_MOUSE,Mus musculus (Mouse),calcium-mediated signaling using intracellular calcium source [GO:0035584]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; mitophagy [GO:0000422]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peroxisome fission [GO:0016559]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314]; protein homooligomerization [GO:0051260]; protein targeting to mitochondrion [GO:0006626]; regulation of mitochondrion organization [GO:0010821]; release of cytochrome c from mitochondria [GO:0001836] comp123935_c0_seq1,906,42.8256,0.62043472,28,32,,3.00E-49,P08487,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0005509; GO:0071364; GO:0001701; GO:0035556; GO:0030027; GO:0004435; GO:0005543; GO:0009395; GO:0010634; GO:0001726; GO:0004871,COP9 signalosome; calcium ion binding; cellular response to epidermal growth factor stimulus; in utero embryonic development; intracellular signal transduction; lamellipodium; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; positive regulation of epithelial cell migration; ruffle; signal transducer activity,PF00168;PF00388;PF00387;PF00017;PF00018;,,,,,,,,,PLCG1_BOVIN,Bos taurus (Bovine),cellular response to epidermal growth factor stimulus [GO:0071364]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634] comp123942_c0_seq1,945,40.9524,0.35457311,39,66,,5.00E-88,Q3T0G5,Proline synthase co-transcribed bacterial homolog protein,Proline synthase co-transcribed bacterial homolog protein,GO:0005739; GO:0030170,mitochondrion; pyridoxal phosphate binding,PF01168;,7.00E-37,CHOYP_BRAFLDRAFT_126227.1.1,,,,,,,PROSC_BOVIN,Bos taurus (Bovine), comp123946_c0_seq1,1476,43.8347,0.32618647,14,52,,7.00E-15,Q6NUZ2,Protein tweety homolog 2-like,Protein tweety homolog 2-like,GO:0005254; GO:0034707; GO:0005886,chloride channel activity; chloride channel complex; plasma membrane,PF04906;,,,,,,,,,TTY2L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp123946_c0_seq2,980,46.7347,0.39302926,0,2,,2.00E-10,Q9U6L4,Protein tweety (Dttyh1),Protein tweety (Dttyh1),GO:0005254; GO:0034707; GO:0005886,chloride channel activity; chloride channel complex; plasma membrane,PF04906;,,,,,,,,,TTY1_DROME,Drosophila melanogaster (Fruit fly),chloride transport [GO:0006821] comp123946_c0_seq3,972,47.428,0.42145054,0,4,,2.00E-25,Q7ZWN9,Protein tweety homolog 2,Protein tweety homolog 2,GO:0005254; GO:0034707; GO:0005886,chloride channel activity; chloride channel complex; plasma membrane,PF04906;,,,,,,,,,TTYH2_XENLA,Xenopus laevis (African clawed frog), comp123947_c0_seq1,751,43.9414,0.46972452,26,14,,4.00E-98,Q9ESR9,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0016887; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0005765; GO:0005815; GO:0032383; GO:0006357; GO:0048545; GO:0006810,ATP binding; ATPase activity; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lysosomal membrane; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to steroid hormone stimulus; transport,PF00005;,2.00E-12,CHOYP_TRIADDRAFT_10137.1.1,,,,,,,ABCA2_RAT,Rattus norvegicus (Rat),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp123951_c0_seq1,512,43.5547,0.54441024,0,0,,3.00E-18,Q6ZVT6,Uncharacterized protein C3orf67,Uncharacterized protein C3orf67,,,PF05018;,,,,,,,,,CC067_HUMAN,Homo sapiens (Human), comp123951_c0_seq2,1095,39.3607,0.71806131,34,14,,9.00E-57,Q6P2K3,Uncharacterized protein C3orf67 homolog,Uncharacterized protein C3orf67 homolog,,,PF05018;,4.00E-15,CHOYP_NEMVEDRAFT_V1G238528.1.1,,,,,,,CC067_MOUSE,Mus musculus (Mouse), comp123954_c0_seq2,1553,47.9717,0.50355728,62,44,,7.00E-16,Q03601,RING finger protein nhl-1,RING finger protein nhl-1,GO:0008270,zinc ion binding,PF01436;PF00097;,,,,,,,,,NHL1_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567] comp123956_c1_seq1,1984,45.6653,0.64536962,84,165,,0,Q9Z2Z9,Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2),Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2),GO:0006048; GO:0030246; GO:0016051; GO:0006541; GO:0004360,UDP-N-acetylglucosamine biosynthetic process; carbohydrate binding; carbohydrate biosynthetic process; glutamine metabolic process; glutamine-fructose-6-phosphate transaminase (isomerizing) activity,PF01380;,0,CHOYP_PHUM_PHUM536560.2.2,,,,,,,GFPT2_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] comp123969_c0_seq1,524,38.9313,0.55555758,60,137,,1.00E-41,P61025,Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334),Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334),GO:0007049; GO:0051301; GO:0016538,cell cycle; cell division; cyclin-dependent protein serine/threonine kinase regulator activity,PF01111;,2.00E-46,CHOYP_BRAFLDRAFT_59154.1.3,,,,,,,CKS1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]" comp123977_c1_seq1,852,42.3709,0.3930881,40,20,,7.00E-89,O54923,Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1) (rSec15),Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1) (rSec15),GO:0000145; GO:0015031; GO:0006904,exocyst; protein transport; vesicle docking involved in exocytosis,PF04091;,,,,,,,,,EXOC6_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp123977_c3_seq2,814,41.0319,0.32341319,31,28,,2.00E-89,A6H5Z3,Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2),Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2),GO:0000145; GO:0006904,exocyst; vesicle docking involved in exocytosis,PF04091;,4.00E-122,CHOYP_EXC6B.1.1,,,,,,,EXC6B_MOUSE,Mus musculus (Mouse),vesicle docking involved in exocytosis [GO:0006904] comp123981_c1_seq1,390,44.1026,0.66019852,14,39,,4.00E-43,P15882,N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2),N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2),GO:0005096; GO:0005070; GO:0005829; GO:0048013; GO:0046872; GO:0008045; GO:0043547; GO:0032314; GO:0050770; GO:0051056; GO:0007264,GTPase activator activity; SH3/SH2 adaptor activity; cytosol; ephrin receptor signaling pathway; metal ion binding; motor neuron axon guidance; positive regulation of GTPase activity; regulation of Rac GTPase activity; regulation of axonogenesis; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF00620;PF00017;,9.00E-44,CHOYP_BRAFLDRAFT_219059.1.1,,,,,,,CHIN_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; regulation of small GTPase mediated signal transduction [GO:0051056] comp123992_c0_seq3,663,44.3439,0.39992678,12,25,,2.00E-106,Q9XSC3,WD repeat-containing protein 44 (Rab11-binding protein) (Rabphilin-11),WD repeat-containing protein 44 (Rab11-binding protein) (Rabphilin-11),GO:0005794; GO:0005829; GO:0010008; GO:0048471,Golgi apparatus; cytosol; endosome membrane; perinuclear region of cytoplasm,PF00400;,,,,,,,,,WDR44_BOVIN,Bos taurus (Bovine), comp123992_c1_seq1,241,42.7386,0.54752074,1,22,,,,,,,,,1.00E-25,CHOYP_WDR44.1.1,,,,,,,,, comp123995_c0_seq1,1364,40.8358,0.61720055,630,1718,,3.00E-177,P50750,Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit),Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit),GO:0005524; GO:0003677; GO:0006281; GO:0016605; GO:0008353; GO:0008283; GO:0071345; GO:0003682; GO:0004693; GO:0005737; GO:0071157; GO:0045944; GO:0050434; GO:0008024; GO:0006282; GO:0031056; GO:0043111; GO:0017069; GO:0006368; GO:0006367; GO:0044212; GO:0007179; GO:0016032,ATP binding; DNA binding; DNA repair; PML body; RNA polymerase II carboxy-terminal domain kinase activity; cell proliferation; cellular response to cytokine stimulus; chromatin binding; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; negative regulation of cell cycle arrest; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; positive transcription elongation factor complex b; regulation of DNA repair; regulation of histone modification; replication fork arrest; snRNA binding; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription regulatory region DNA binding; transforming growth factor beta receptor signaling pathway; viral process,PF00069;,2.00E-147,CHOYP_CDK9.1.1,,,4.00E-96,AM867308.p.cg.6,3,,CDK9_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp12399_c0_seq1,203,50.2463,0.78463442,0,2,,4.00E-16,Q797S1,Putative PTS system EIIBC component YbbF [Includes: Phosphotransferase enzyme IIB component (EC 2.7.1.69) (PTS system EIIB component); Permease IIC component (PTS system EIIC component)],Putative PTS system EIIBC component YbbF [Includes: Phosphotransferase enzyme IIB component (EC 2.7.1.-) (PTS system EIIB component); Permease IIC component (PTS system EIIC component)],GO:0016021; GO:0016301; GO:0009401; GO:0005886; GO:0008982; GO:0005351,integral to membrane; kinase activity; phosphoenolpyruvate-dependent sugar phosphotransferase system; plasma membrane; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; sugar:hydrogen symporter activity,PF00367;PF02378;,,,,,,,,,PTXBC_BACSU,Bacillus subtilis (strain 168),phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of carbohydrate utilization [GO:0043610] comp124003_c0_seq3,648,33.642,1.20175356,3,30,,1.00E-36,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp124005_c1_seq1,368,44.2935,0.71651015,6,42,,8.00E-14,Q9FE17,NAD-dependent protein deacetylase SRT1 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1),NAD-dependent protein deacetylase SRT1 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1),GO:0070403; GO:0016787; GO:0046872; GO:0005634,NAD+ binding; hydrolase activity; metal ion binding; nucleus,PF02146;,2.00E-25,CHOYP_LOC100632618.3.3,,,,,,,SIR1_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp124007_c0_seq1,539,49.1651,0.49896222,0,5,,6.00E-85,Q80XJ3,Tetratricopeptide repeat protein 28 (TPR repeat protein 28),Tetratricopeptide repeat protein 28 (TPR repeat protein 28),GO:0051301; GO:0005813; GO:0005737; GO:0030496; GO:0007067; GO:1990023; GO:0097431; GO:0007346,cell division; centrosome; cytoplasm; midbody; mitosis; mitotic spindle midzone; mitotic spindle pole; regulation of mitotic cell cycle,PF12770;PF13176;,9.00E-109,CHOYP_TTC28.1.1,,,,,,,TTC28_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp124007_c0_seq2,374,48.3957,0.69444941,0,0,,1.00E-07,Q940U6,"Protein FLUORESCENT IN BLUE LIGHT, chloroplastic","Protein FLUORESCENT IN BLUE LIGHT, chloroplastic",GO:0031969; GO:0009535; GO:0016021,chloroplast membrane; chloroplast thylakoid membrane; integral to membrane,,,,,,,,,,FLU_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp124010_c0_seq1,392,40.051,1.1483841,15,15,,5.00E-11,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp124026_c3_seq1,338,44.9704,0.41544481,12,14,,1.00E-61,Q20CR4,Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),GO:0005524; GO:0005737; GO:0045111; GO:0005634; GO:0018108; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; intermediate filament cytoskeleton; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF07714;,5.00E-52,CHOYP_NEMVEDRAFT_V1G241055.1.1,,,,,,,DUSTY_MACMU,Macaca mulatta (Rhesus macaque),cellular response to fibroblast growth factor stimulus [GO:0044344]; intracellular signal transduction [GO:0035556]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of kinase activity [GO:0033674]; protein phosphorylation [GO:0006468] comp124031_c0_seq2,583,44.7684,0.77165392,0,0,,5.00E-07,Q98902,Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (L1-CAM),Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (L1-CAM),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF13882;PF00041;PF07679;,,,,,,,,,L1CAM_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),cell adhesion [GO:0007155]; positive regulation of axon extension [GO:0045773] comp124032_c0_seq1,916,41.7031,0.43306438,280,1704,,3.00E-105,Q96B26,Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9),Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9),GO:0017091; GO:0005829; GO:0043928; GO:0000178; GO:0010467; GO:0005730; GO:0005634; GO:0006364,AU-rich element binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; exosome (RNase complex); gene expression; nucleolus; nucleus; rRNA processing,PF01138;PF03725;,2.00E-50,CHOYP_LOC100373657.1.1,1.00E-81,ruditapes_c19102,,,,,EXOS8_HUMAN,Homo sapiens (Human),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; regulation of mRNA stability [GO:0043488]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" comp124035_c0_seq2,516,40.3101,0.73667988,29,3,,2.00E-08,Q8K1C7,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT14_MOUSE,Mus musculus (Mouse), comp124036_c0_seq1,981,38.3282,0.44778888,384,1105,,6.00E-24,Q9NRX2,"39S ribosomal protein L17, mitochondrial (L17mt) (MRP-L17) (LYST-interacting protein 2)","39S ribosomal protein L17, mitochondrial (L17mt) (MRP-L17) (LYST-interacting protein 2)",GO:0005743; GO:0005840; GO:0003735; GO:0006412,mitochondrial inner membrane; ribosome; structural constituent of ribosome; translation,PF01196;,,,1.00E-26,ruditapes_c1405,,,,,RM17_HUMAN,Homo sapiens (Human),mitochondrial genome maintenance [GO:0000002]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126] comp124039_c0_seq1,1386,42.6407,0.48443961,0,0,,8.00E-39,P58283,E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1),E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1),GO:0006915; GO:0005737; GO:0016874; GO:0043161; GO:0070936; GO:0050691; GO:0032648; GO:0008270,apoptotic process; cytoplasm; ligase activity; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; regulation of defense response to virus by host; regulation of interferon-beta production; zinc ion binding,,1.00E-11,CHOYP_BRAFLDRAFT_117374.1.1,,,,,,,RN216_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648] comp124039_c0_seq2,1842,40.608,0.44184735,15,26,,,,,,,,,8.00E-40,CHOYP_LOC100142249.1.1,,,,,,,,, comp124054_c0_seq1,711,30.2391,0.82820493,3384,6470,,4.00E-12,Q9XY35,Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Protein oxen) (Ubiquinol-cytochrome c reductase complex 6.3 kDa protein),Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Protein oxen) (Ubiquinol-cytochrome c reductase complex 6.3 kDa protein),GO:0006122; GO:0005750; GO:0007286,"mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial respiratory chain complex III; spermatid development",PF05365;,,,,,,,,,QCR9_DROME,Drosophila melanogaster (Fruit fly),"aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]; sensory perception of pain [GO:0019233]; spermatid development [GO:0007286]" comp124055_c0_seq1,6631,45.981,0.72126531,126,2018,,0,P24733,"Myosin heavy chain, striated muscle","Myosin heavy chain, striated muscle",GO:0005524; GO:0003774; GO:0030016; GO:0032982,ATP binding; motor activity; myofibril; myosin filament,PF00063;PF02736;PF01576;,0,CHOYP_MYS.2.7,8.00E-63,ruditapes2_c322,,,,,MYS_AEQIR,Argopecten irradians (Bay scallop) (Aequipecten irradians), comp124055_c0_seq2,6699,46.0516,0.7227068,54,890,,0,P49824,"Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)","Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)",GO:0005524; GO:0003774; GO:0030016; GO:0032982,ATP binding; motor activity; myofibril; myosin filament,PF00063;PF02736;PF01576;,2.00E-15,CHOYP_MYO5A.1.4,1.00E-124,ruditapes2_c3813,,,,,MYH7_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp124055_c0_seq3,6718,46.0107,0.72510342,41,1029,,0,P24733,"Myosin heavy chain, striated muscle","Myosin heavy chain, striated muscle",GO:0005524; GO:0003774; GO:0030016; GO:0032982,ATP binding; motor activity; myofibril; myosin filament,PF00063;PF02736;PF01576;,0,CHOYP_MYS.2.7,3.00E-125,ruditapes_c29187,6.00E-151,CU686207.p.cg.6,1,adductor muscle,MYS_AEQIR,Argopecten irradians (Bay scallop) (Aequipecten irradians), comp124056_c0_seq1,1103,39.8912,0.33025668,45,161,,6.00E-23,Q96GR4,Probable palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 12) (DHHC-12) (Zinc finger protein 400),Probable palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 12) (DHHC-12) (Zinc finger protein 400),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,4.00E-34,CHOYP_LOC590681.2.2,3.00E-65,ruditapes_c15479,,,,,ZDH12_HUMAN,Homo sapiens (Human),protein palmitoylation [GO:0018345] comp124057_c0_seq1,1005,41.791,1.01034087,559,7,,,,,,,,,,,6.00E-17,ruditapes_c15382,,,,,,, comp124057_c0_seq2,1196,40.301,1.09320796,1187,22,,2.00E-07,Q5VZQ5,Testis-expressed sequence 36 protein,Testis-expressed sequence 36 protein,,,PF15115;,,,,,,,,,TEX36_HUMAN,Homo sapiens (Human), comp124061_c0_seq1,690,39.7101,0.82583833,26,73,,4.00E-42,Q9UI43,Putative ribosomal RNA methyltransferase 2 (EC 2.1.1.-) (Protein ftsJ homolog 2) (rRNA (uridine-2'-O-)-methyltransferase),"rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2)",GO:0008283; GO:0005739; GO:0005730; GO:0008650,cell proliferation; mitochondrion; nucleolus; rRNA (uridine-2'-O-)-methyltransferase activity,PF01728;,,,,,,,,,RRMJ2_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; enzyme-directed rRNA 2'-O-methylation [GO:0000453]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364] comp124068_c1_seq1,1105,44.1629,0.74488208,77,41,,8.00E-149,Q5ZJ41,E3 ubiquitin-protein ligase MARCH5 (EC 6.3.2.-) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V),E3 ubiquitin-protein ligase MARCH5 (EC 6.3.2.-) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V),GO:0005783; GO:0005789; GO:0016021; GO:0005741; GO:0090344; GO:0090141; GO:0051865; GO:0070585; GO:0000209; GO:0090140; GO:0004842; GO:0008270,endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; mitochondrial outer membrane; negative regulation of cell aging; positive regulation of mitochondrial fission; protein autoubiquitination; protein localization to mitochondrion; protein polyubiquitination; regulation of mitochondrial fission; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,3.00E-87,CHOYP_LOC100378338.1.1,,,,,,,MARH5_CHICK,Gallus gallus (Chicken),negative regulation of cell aging [GO:0090344]; positive regulation of mitochondrial fission [GO:0090141]; protein autoubiquitination [GO:0051865]; protein localization to mitochondrion [GO:0070585]; protein polyubiquitination [GO:0000209]; regulation of mitochondrial fission [GO:0090140] comp124075_c0_seq1,353,41.9263,0.79018491,5,62,,2.00E-20,Q95333,Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2),Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2),GO:0004177; GO:0031225; GO:0009987; GO:0046872; GO:0008237; GO:0005886; GO:0006508,aminopeptidase activity; anchored to membrane; cellular process; metal ion binding; metallopeptidase activity; plasma membrane; proteolysis,PF01321;PF00557;PF16188;,,,,,,,,,XPP2_PIG,Sus scrofa (Pig), comp124076_c0_seq1,648,41.2037,0.42580323,48,362,,4.00E-27,Q9BSF4,Uncharacterized protein C19orf52,Uncharacterized protein C19orf52,,,PF10171;,,,,,,,,,CS052_HUMAN,Homo sapiens (Human), comp124078_c0_seq1,934,32.9764,0.27598598,1216,2330,,,,,,,,,2.00E-49,CHOYP_SF3B5.1.1,,,,,,,,, comp124078_c0_seq2,1075,37.6744,0.34112111,0,1,,2.00E-47,Q9VHI4,Probable splicing factor 3B subunit 5 (SF3b5) (Pre-mRNA-splicing factor SF3b 10 kDa subunit),Probable splicing factor 3B subunit 5 (SF3b5) (Pre-mRNA-splicing factor SF3b 10 kDa subunit),GO:0000398; GO:0007052; GO:0071011,"mRNA splicing, via spliceosome; mitotic spindle organization; precatalytic spliceosome",PF07189;,3.00E-49,CHOYP_SF3B5.1.1,2.00E-35,ruditapes_c15609,,,,,SF3B5_DROME,Drosophila melanogaster (Fruit fly),"mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]" comp124080_c1_seq1,844,50,0.44090352,26,46,,7.00E-82,B3DLH6,Myoferlin (Fer-1-like protein 3),Myoferlin (Fer-1-like protein 3),GO:0005901; GO:0030659; GO:0016021; GO:0031965; GO:0005543; GO:0001778,caveola; cytoplasmic vesicle membrane; integral to membrane; nuclear membrane; phospholipid binding; plasma membrane repair,PF00168;PF08165;PF08150;PF08151;PF16165;,1.00E-96,CHOYP_MYOF.3.3,,,,,,,MYOF_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778] comp124082_c1_seq1,605,41.9835,0.98076832,0,31,,3.00E-54,P51589,Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),GO:0008405; GO:0008404; GO:0070330; GO:0005789; GO:0019373; GO:0020037; GO:0005506; GO:0071614; GO:0043651; GO:0008016; GO:0006805,"arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; aromatase activity; endoplasmic reticulum membrane; epoxygenase P450 pathway; heme binding; iron ion binding; linoleic acid epoxygenase activity; linoleic acid metabolic process; regulation of heart contraction; xenobiotic metabolic process",PF00067;,,,,,,,,,CP2J2_HUMAN,Homo sapiens (Human),epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805] comp124082_c1_seq2,528,39.9621,1.09435543,0,13,,1.00E-27,Q6ZSU1,Putative inactive cytochrome P450 2G1 (Cytochrome P450 2G1 pseudogene),Putative inactive cytochrome P450 2G1 (Cytochrome P450 2G1 pseudogene),GO:0020037; GO:0005506; GO:0016705,"heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C2G1P_HUMAN,Homo sapiens (Human), comp124088_c0_seq1,749,40.5874,0.39640663,48,117,,2.00E-56,Q9WUB4,Dynactin subunit 6 (Dynactin subunit p27) (Protein WS-3),Dynactin subunit 6 (Dynactin subunit p27) (Protein WS-3),GO:0003824; GO:0005813; GO:0000777; GO:0005869; GO:0045502; GO:0008610; GO:0005739; GO:0007005,catalytic activity; centrosome; condensed chromosome kinetochore; dynactin complex; dynein binding; lipid biosynthetic process; mitochondrion; mitochondrion organization,PF00132;,7.00E-42,CHOYP_DCTN6.1.1,,,,,,,DCTN6_MOUSE,Mus musculus (Mouse),lipid biosynthetic process [GO:0008610]; mitochondrion organization [GO:0007005]; mitotic spindle organization [GO:0007052] comp124094_c0_seq1,594,47.8114,0.48484986,10,71,,2.00E-64,Q8CD19,LanC-like protein 3,LanC-like protein 3,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF05147;,2.00E-48,CHOYP_BRAFLDRAFT_76662.3.3,,,,,,,LANC3_MOUSE,Mus musculus (Mouse), comp124099_c0_seq1,407,47.6658,1.17242087,18,130,,3.00E-10,P0DKM9,Turripeptide OL11-like (Fragment),Turripeptide OL11-like (Fragment),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF07648;,,,,,,,,,TU11_LOPAL,Lophiotoma albina (Sea snail) (Xenuroturris albina), comp124103_c1_seq1,691,44.5731,0.44597301,16,27,,5.00E-30,Q8IXV7,Kelch domain-containing protein 8B,Kelch domain-containing protein 8B,GO:0005737,cytoplasm,PF01344;,,,,,,,,,KLD8B_HUMAN,Homo sapiens (Human), comp124103_c3_seq1,534,40.6367,0.41993868,25,24,,2.00E-09,Q503R4,Kelch-like protein 36,Kelch-like protein 36,GO:0016567,protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH36_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp124111_c0_seq2,491,41.7515,1.07915763,3,69,,1.00E-19,Q9VG17,Probable cytochrome P450 304a1 (EC 1.14.-.-) (CYPCCCIVA1),Probable cytochrome P450 304a1 (EC 1.14.-.-) (CYPCCCIVA1),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP304_DROME,Drosophila melanogaster (Fruit fly),insecticide metabolic process [GO:0017143] comp124111_c1_seq1,779,42.7471,0.87640594,15,139,,3.00E-55,P51589,Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),GO:0008405; GO:0008404; GO:0070330; GO:0005789; GO:0019373; GO:0020037; GO:0005506; GO:0071614; GO:0043651; GO:0008016; GO:0006805,"arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; aromatase activity; endoplasmic reticulum membrane; epoxygenase P450 pathway; heme binding; iron ion binding; linoleic acid epoxygenase activity; linoleic acid metabolic process; regulation of heart contraction; xenobiotic metabolic process",PF00067;,,,,,,,,,CP2J2_HUMAN,Homo sapiens (Human),epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805] comp124138_c0_seq1,811,44.143,0.58646658,0,14,,1.00E-44,O97490,Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228),Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228),GO:0031225; GO:0006879; GO:0005576; GO:0008199; GO:0006826; GO:0005886,anchored to membrane; cellular iron ion homeostasis; extracellular region; ferric iron binding; iron ion transport; plasma membrane,PF00405;,1.00E-45,CHOYP_BRAFLDRAFT_124962.1.1,,,,,,,TRFM_RABIT,Oryctolagus cuniculus (Rabbit),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] comp124138_c0_seq2,763,44.9541,0.575578,0,0,,4.00E-33,Q02942,Transferrin,Transferrin,GO:0006879; GO:0005576; GO:0008199; GO:0006826,cellular iron ion homeostasis; extracellular region; ferric iron binding; iron ion transport,PF00405;,,,,,,,,,TRF_BLADI,Blaberus discoidalis (Tropical cockroach),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] comp124138_c1_seq1,558,44.9821,0.59231978,7,124,,1.00E-10,P22297,Transferrin,Transferrin,GO:0006879; GO:0005576; GO:0008199; GO:0006826,cellular iron ion homeostasis; extracellular region; ferric iron binding; iron ion transport,PF00405;,,,,,,,,,TRF_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] comp124140_c0_seq1,846,49.6454,0.3266269,36,32,,,,,,,,,4.00E-39,CHOYP_LOC100367312.6.13,2.00E-78,ruditapes_c23562,,,,,,, comp124145_c0_seq1,897,38.2386,1.04197795,8816,20,male>female,8.00E-25,Q9DAN9,Uncharacterized protein C17orf105 homolog,Uncharacterized protein C17orf105 homolog,,,PF13879;,,,,,,,,,CQ105_MOUSE,Mus musculus (Mouse), comp124153_c0_seq1,778,36.6324,1.00188135,74,1393,,4.00E-29,Q2HJ57,Coactosin-like protein,Coactosin-like protein,GO:0005737; GO:0005856; GO:0050832; GO:0031965,cytoplasm; cytoskeleton; defense response to fungus; nuclear membrane,PF00241;,,,3.00E-39,ruditapes2_c1370,,,,,COTL1_BOVIN,Bos taurus (Bovine),defense response to fungus [GO:0050832] comp124156_c0_seq1,525,41.7143,1.0091795,9,78,,,,,,,,,9.00E-20,CHOYP_BRAFLDRAFT_106563.4.5,,,,,,,,, comp124168_c1_seq2,446,44.3946,0.64086344,5,16,,1.00E-60,O43293,Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase),Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase),GO:0005524; GO:0016605; GO:0006915; GO:0071346; GO:0016568; GO:0000775; GO:0000910; GO:0005737; GO:0007243; GO:0005815; GO:0017148; GO:0030182; GO:0005634; GO:0090263; GO:2001241; GO:0046777; GO:0042803; GO:0004674; GO:2000249; GO:0042981; GO:0010506; GO:2000145; GO:0007088; GO:0006940; GO:0006355; GO:0006351,"ATP binding; PML body; apoptotic process; cellular response to interferon-gamma; chromatin modification; chromosome, centromeric region; cytokinesis; cytoplasm; intracellular protein kinase cascade; microtubule organizing center; negative regulation of translation; neuron differentiation; nucleus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; regulation of actin cytoskeleton reorganization; regulation of apoptotic process; regulation of autophagy; regulation of cell motility; regulation of mitosis; regulation of smooth muscle contraction; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;,,,,,,,,,DAPK3_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; chromatin modification [GO:0016568]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; regulation of myosin II filament organization [GO:0043519]; regulation of smooth muscle contraction [GO:0006940]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124168_c1_seq4,446,43.722,0.51790865,0,0,,2.00E-14,Q91604,Serine/threonine-protein kinase stk11 (EC 2.7.11.1) (Liver kinase B1 homolog) (lkb1) (Serine/threonine-protein kinase XEEK1),Serine/threonine-protein kinase stk11 (EC 2.7.11.1) (Liver kinase B1 homolog) (lkb1) (Serine/threonine-protein kinase XEEK1),GO:0005524; GO:0007049; GO:0005829; GO:0030010; GO:0042593; GO:0072332; GO:0016020; GO:0046872; GO:0005739; GO:0030308; GO:0005634; GO:0002039; GO:0046777; GO:0030295; GO:0004674; GO:0006974; GO:0010212; GO:0001944,ATP binding; cell cycle; cytosol; establishment of cell polarity; glucose homeostasis; intrinsic apoptotic signaling pathway by p53 class mediator; membrane; metal ion binding; mitochondrion; negative regulation of cell growth; nucleus; p53 binding; protein autophosphorylation; protein kinase activator activity; protein serine/threonine kinase activity; response to DNA damage stimulus; response to ionizing radiation; vasculature development,PF00069;,,,,,,,,,STK11_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; response to ionizing radiation [GO:0010212]; vasculature development [GO:0001944] comp124175_c0_seq1,241,45.2282,0.5762004,2,27,,1.00E-17,P51955,Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1),Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1),GO:0005524; GO:0000086; GO:0001824; GO:0051301; GO:0005813; GO:0051299; GO:0007059; GO:0000777; GO:0000794; GO:0005829; GO:0000776; GO:0007126; GO:0046872; GO:0005874; GO:0030496; GO:0007067; GO:0000070; GO:0043392; GO:0005730; GO:0046777; GO:0004674; GO:0051988; GO:0046602; GO:0051225; GO:0090307; GO:0000922,ATP binding; G2/M transition of mitotic cell cycle; blastocyst development; cell division; centrosome; centrosome separation; chromosome segregation; condensed chromosome kinetochore; condensed nuclear chromosome; cytosol; kinetochore; meiosis; metal ion binding; microtubule; midbody; mitosis; mitotic sister chromatid segregation; negative regulation of DNA binding; nucleolus; protein autophosphorylation; protein serine/threonine kinase activity; regulation of attachment of spindle microtubules to kinetochore; regulation of mitotic centrosome separation; spindle assembly; spindle assembly involved in mitosis; spindle pole,PF00069;,,,,,,,,,NEK2_HUMAN,Homo sapiens (Human),blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] comp124175_c1_seq1,206,47.5728,0.4327025,4,2,,3.00E-35,P51955,Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1),Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1),GO:0005524; GO:0000086; GO:0001824; GO:0051301; GO:0005813; GO:0051299; GO:0007059; GO:0000777; GO:0000794; GO:0005829; GO:0000776; GO:0007126; GO:0046872; GO:0005874; GO:0030496; GO:0007067; GO:0000070; GO:0043392; GO:0005730; GO:0046777; GO:0004674; GO:0051988; GO:0046602; GO:0051225; GO:0090307; GO:0000922,ATP binding; G2/M transition of mitotic cell cycle; blastocyst development; cell division; centrosome; centrosome separation; chromosome segregation; condensed chromosome kinetochore; condensed nuclear chromosome; cytosol; kinetochore; meiosis; metal ion binding; microtubule; midbody; mitosis; mitotic sister chromatid segregation; negative regulation of DNA binding; nucleolus; protein autophosphorylation; protein serine/threonine kinase activity; regulation of attachment of spindle microtubules to kinetochore; regulation of mitotic centrosome separation; spindle assembly; spindle assembly involved in mitosis; spindle pole,PF00069;,9.00E-40,CHOYP_NEK2.2.3,,,,,,,NEK2_HUMAN,Homo sapiens (Human),blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] comp124183_c0_seq2,483,44.7205,0.41670433,17,90,,,,,,,,,3.00E-19,CHOYP_LOC100378550.1.1,,,,,,,,, comp124183_c1_seq1,504,41.8651,0.40909252,18,37,,1.00E-33,Q8VEH8,Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin),Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin),GO:0030433; GO:0005788; GO:0001948,ER-associated protein catabolic process; endoplasmic reticulum lumen; glycoprotein binding,PF07915;,,,,,,,,,ERLEC_MOUSE,Mus musculus (Mouse),"ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; retrograde protein transport, ER to cytosol [GO:0030970]" comp124198_c0_seq1,610,38.3607,0.5375381,5,154,,3.00E-07,P0CY12,Putative mating-type protein A2 (MATa2 protein),Putative mating-type protein A2 (MATa2 protein),GO:0005634; GO:0043565; GO:0003700,nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;,,,,,,,,,MATA2_YEASX,Saccharomyces cerevisiae (Baker's yeast), comp124209_c0_seq1,265,35.8491,0.82756734,0,10,,2.00E-08,Q6PH37,Cytosolic sulfotransferase 1 (EC 2.8.2.-) (SULT1 ST1),Cytosolic sulfotransferase 1 (EC 2.8.2.-) (SULT1 ST1),GO:0006584; GO:0005737; GO:0008146; GO:0006805,catecholamine metabolic process; cytoplasm; sulfotransferase activity; xenobiotic metabolic process,PF00685;,7.00E-11,CHOYP_ST1B1.4.4,,,,,,,ST1S1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),catecholamine metabolic process [GO:0006584]; xenobiotic metabolic process [GO:0006805] comp124216_c0_seq1,857,42.007,0.74334084,60,16,,3.00E-35,Q7TS72,"Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C)","Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C)",GO:0005524; GO:0005737; GO:0008440; GO:0005634,"ATP binding; cytoplasm; inositol-1,4,5-trisphosphate 3-kinase activity; nucleus",PF03770;,1.00E-64,CHOYP_LOC100878101.1.2,,,,,,,IP3KC_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp124217_c1_seq1,717,41.2831,0.92496154,0,84,,2.00E-32,P86786,Gigasin-3a (Fragment),Gigasin-3a (Fragment),GO:0016787; GO:0009166,hydrolase activity; nucleotide catabolic process,,,,,,,,,,GIGA3_CRAGI,Crassostrea gigas (Pacific oyster) (Crassostrea angulata), comp124222_c0_seq1,1073,41.8453,0.8851063,57,116,,8.00E-50,Q3TUU5,Testis-expressed sequence 30 protein,Testis-expressed sequence 30 protein,,,PF01738;,,,,,,,,,TEX30_MOUSE,Mus musculus (Mouse), comp124226_c0_seq1,966,38.9234,0.47157251,5,290,,4.00E-08,Q69DL0,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit A,GO:0005581; GO:0006958; GO:0045087,"collagen; complement activation, classical pathway; innate immune response",PF00386;PF01391;,,,,,,,,,C1QA_PIG,Sus scrofa (Pig),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]" comp124231_c0_seq1,460,39.5652,0.84743048,2,30,,5.00E-34,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,4.00E-11,CHOYP_LOC100366344.1.1,,,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp124243_c0_seq2,914,39.3873,0.70636819,47,18,,3.00E-27,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,8.00E-11,CHOYP_LOC100484022.2.2,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124258_c0_seq2,629,46.7409,1.04975965,0,43,,7.00E-09,Q68SA9,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS7_MOUSE,Mus musculus (Mouse),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp124259_c1_seq1,301,43.8538,0.55515319,2,0,,8.00E-13,Q9PK00,Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog),Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog),GO:0003723; GO:0016070; GO:0005737; GO:0008859; GO:0090305,RNA binding; RNA metabolic process; cytoplasm; exoribonuclease II activity; nucleic acid phosphodiester bond hydrolysis,PF08206;,,,,,,,,,RNR_CHLMU,Chlamydia muridarum (strain MoPn / Nigg), comp124260_c0_seq1,215,42.7907,1.44622928,0,0,,7.00E-07,Q61554,Fibrillin-1,Fibrillin-1 [Cleaved into: Asprosin],GO:0005509; GO:0005201; GO:0001527; GO:0035582; GO:0035583,calcium ion binding; extracellular matrix structural constituent; microfibril; sequestering of BMP in extracellular matrix; sequestering of TGFbeta in extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN1_MOUSE,Mus musculus (Mouse),activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] comp124260_c0_seq4,239,38.4937,1.37735553,0,0,,3.00E-07,P98069,Bone morphogenetic protein 1 homolog (EC 3.4.24.-) (SUBMP),Bone morphogenetic protein 1 homolog (EC 3.4.24.-) (SUBMP),GO:0005509; GO:0004222; GO:0007275; GO:0006508; GO:0008270,calcium ion binding; metalloendopeptidase activity; multicellular organismal development; proteolysis; zinc ion binding,PF01400;PF00431;,,,,,,,,,BMPH_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),multicellular organism development [GO:0007275] comp124266_c0_seq1,600,43.8333,0.56115936,3,118,,2.00E-38,P36189,Fatty acid synthase (EC 2.3.1.85) (Fragment),Fatty acid synthase (EC 2.3.1.85) (Fragment),GO:0006633; GO:0004312; GO:0016787; GO:0016874; GO:0016491,fatty acid biosynthetic process; fatty acid synthase activity; hydrolase activity; ligase activity; oxidoreductase activity,PF00109;PF02801;,,,,,,,,,FAS_ANSAN,Anser anser anser (Western greylag goose),fatty acid biosynthetic process [GO:0006633] comp124266_c1_seq1,856,44.743,0.40188182,0,138,,5.00E-57,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,8.00E-17,CHOYP_FASN.2.4,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp124268_c0_seq1,1211,43.6829,0.55841314,5705,22893,,2.00E-135,Q2TBP0,Proteasome subunit beta type-7 (EC 3.4.25.1),Proteasome subunit beta type-7 (EC 3.4.25.1),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF12465;PF00227;,4.00E-124,CHOYP_LOC100370401.1.1,2.00E-169,ruditapes2_c1058,7.00E-120,AM864705.p.cg.6,8,,PSB7_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp124269_c0_seq1,1116,44.3548,0.37150394,40,69,,1.00E-24,P33224,Putative acyl-CoA dehydrogenase AidB (EC 1.3.99.-),Putative acyl-CoA dehydrogenase AidB (EC 1.3.99.-),GO:0005737; GO:0008470; GO:0045892; GO:0006950; GO:0043565,"cytoplasm; isovaleryl-CoA dehydrogenase activity; negative regulation of transcription, DNA-dependent; response to stress; sequence-specific DNA binding",PF00441;PF02770;,3.00E-43,CHOYP_LOC100711593.1.1,,,,,,,AIDB_ECOLI,Escherichia coli (strain K12),"cellular response to DNA damage stimulus [GO:0006974]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]" comp124272_c0_seq1,561,42.0677,0.48717918,5,73,,1.00E-27,A0JNB1,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124274_c2_seq1,486,36.6255,0.369314,9,59,,,,,,,,,,,9.00E-11,ruditapes_c9791,,,,,,, comp124274_c3_seq1,1184,40.9628,0.38333871,23,108,,9.00E-88,Q5ZL12,Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1),Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1),GO:0019902,phosphatase binding,PF10205;PF10212;,2.00E-84,CHOYP_BRAFLDRAFT_276229.1.1,,,,,,,PPR21_CHICK,Gallus gallus (Chicken), comp124278_c0_seq1,307,38.1107,0.27731387,8,41,,,,,,,,,6.00E-19,CHOYP_NEMVEDRAFT_V1G247129.3.3,,,,,,,,, comp124279_c0_seq1,237,38.3966,1.16099628,16,20,,2.00E-42,P35286,Ras-related protein Rab-13,Ras-related protein Rab-13,GO:0005525; GO:0006184; GO:0003924; GO:0005794; GO:0032869; GO:0030866; GO:0030659; GO:0032456; GO:0030139; GO:0035767; GO:0097368; GO:0090002; GO:0042593; GO:0032593; GO:0030027; GO:0016328; GO:0043005; GO:0031175; GO:0046326; GO:0010737; GO:0015031; GO:0055037; GO:0055038; GO:0007264; GO:0005923; GO:0070830; GO:0005802; GO:0044795; GO:0030658,GTP binding; GTP catabolic process; GTPase activity; Golgi apparatus; cellular response to insulin stimulus; cortical actin cytoskeleton organization; cytoplasmic vesicle membrane; endocytic recycling; endocytic vesicle; endothelial cell chemotaxis; establishment of Sertoli cell barrier; establishment of protein localization to plasma membrane; glucose homeostasis; insulin-responsive compartment; lamellipodium; lateral plasma membrane; neuron projection; neuron projection development; positive regulation of glucose import; protein kinase A signaling cascade; protein transport; recycling endosome; recycling endosome membrane; small GTPase mediated signal transduction; tight junction; tight junction assembly; trans-Golgi network; trans-Golgi network to recycling endosome transport; transport vesicle membrane,PF00071;,1.00E-58,CHOYP_RAB8A.2.3,4.00E-30,ruditapes_c7176,,,,,RAB13_RAT,Rattus norvegicus (Rat),bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endothelial cell chemotaxis [GO:0035767]; establishment of protein localization to plasma membrane [GO:0090002]; establishment of Sertoli cell barrier [GO:0097368]; glucose homeostasis [GO:0042593]; membrane organization [GO:0061024]; neuron projection development [GO:0031175]; positive regulation of glucose import [GO:0046326]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; small GTPase mediated signal transduction [GO:0007264]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] comp124279_c1_seq1,629,37.2019,0.52659708,32,130,,6.00E-65,P35280,Ras-related protein Rab-8A,Ras-related protein Rab-8A,GO:0019003; GO:0005525; GO:0003924; GO:0005794; GO:0048210; GO:0007409; GO:0032869; GO:0042384; GO:0030659; GO:0030425; GO:0042593; GO:0005932; GO:0043025; GO:0031513; GO:0048471; GO:0045335; GO:0030670; GO:0005886; GO:0046326; GO:0014069; GO:0072659; GO:0015031; GO:0055038; GO:0048169; GO:0051223; GO:0007264; GO:0006904,GDP binding; GTP binding; GTPase activity; Golgi apparatus; Golgi vesicle fusion to target membrane; axonogenesis; cellular response to insulin stimulus; cilium assembly; cytoplasmic vesicle membrane; dendrite; glucose homeostasis; microtubule basal body; neuronal cell body; nonmotile primary cilium; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; positive regulation of glucose import; postsynaptic density; protein localization to plasma membrane; protein transport; recycling endosome membrane; regulation of long-term neuronal synaptic plasticity; regulation of protein transport; small GTPase mediated signal transduction; vesicle docking involved in exocytosis,PF00071;,5.00E-56,CHOYP_RAB8A.1.3,,,,,,,RAB8A_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0042384]; glucose homeostasis [GO:0042593]; Golgi vesicle fusion to target membrane [GO:0048210]; membrane organization [GO:0061024]; positive regulation of glucose import [GO:0046326]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein localization [GO:0032880]; regulation of protein transport [GO:0051223]; small GTPase mediated signal transduction [GO:0007264]; vesicle docking involved in exocytosis [GO:0006904] comp124280_c0_seq1,600,44,0.48568595,9,52,,1.00E-59,P46662,Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin),Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin),GO:0014010; GO:0030036; GO:0005912; GO:0045216; GO:0032154; GO:0030864; GO:0005769; GO:0007398; GO:0019898; GO:0030175; GO:0030027; GO:0070306; GO:0001707; GO:0008156; GO:0043409; GO:0008285; GO:0022408; GO:0006469; GO:0042518; GO:0042524; GO:0005730; GO:0005634; GO:0042475; GO:0048471; GO:0005886; GO:0051496; GO:0035330; GO:0001726,Schwann cell proliferation; actin cytoskeleton organization; adherens junction; cell-cell junction organization; cleavage furrow; cortical actin cytoskeleton; early endosome; ectoderm development; extrinsic to membrane; filopodium; lamellipodium; lens fiber cell differentiation; mesoderm formation; negative regulation of DNA replication; negative regulation of MAPK cascade; negative regulation of cell proliferation; negative regulation of cell-cell adhesion; negative regulation of protein kinase activity; negative regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of tyrosine phosphorylation of Stat5 protein; nucleolus; nucleus; odontogenesis of dentin-containing tooth; perinuclear region of cytoplasm; plasma membrane; positive regulation of stress fiber assembly; regulation of hippo signaling cascade; ruffle,PF00769;PF09380;PF00373;PF09379;,1.00E-81,CHOYP_MERL.1.1,,,,,,,MERL_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010] comp124284_c0_seq4,776,42.9124,0.95752243,17,1022,,,,,,,,,,,4.00E-31,ruditapes_lrc33451,,,,,,, comp124284_c0_seq5,877,42.6454,0.92966009,23,1170,,2.00E-11,Q9I925,Fucolectin-7,Fucolectin-7,GO:0005509; GO:0007155; GO:0005615; GO:0042806; GO:0010185; GO:0001868,"calcium ion binding; cell adhesion; extracellular space; fucose binding; regulation of cellular defense response; regulation of complement activation, lectin pathway",PF00754;,,,,,,,,,FUCL7_ANGJA,Anguilla japonica (Japanese eel),"regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088]" comp124287_c1_seq1,1027,39.0458,1.12635198,31,209,,6.00E-51,Q6UXP7,Protein FAM151B,Protein FAM151B,,,PF10223;,,,,,,,,,F151B_HUMAN,Homo sapiens (Human), comp124298_c0_seq1,720,42.0833,0.47555276,19,65,,,,,,,,,2.00E-42,CHOYP_TRIADDRAFT_60787.1.1,,,,,,,,, comp124300_c0_seq1,280,36.0714,0.66641166,3,3,,9.00E-14,Q54MF3,Calcineurin subunit B type 2 (Calcineurin regulatory subunit 2) (Protein phosphatase 2B regulatory subunit 2),Calcineurin subunit B type 2 (Calcineurin regulatory subunit 2) (Protein phosphatase 2B regulatory subunit 2),GO:0005509; GO:0006470,calcium ion binding; protein dephosphorylation,PF13499;,,,,,,,,,CANB2_DICDI,Dictyostelium discoideum (Slime mold),protein dephosphorylation [GO:0006470] comp124300_c1_seq1,898,35.078,0.477021,68,64,,5.00E-37,Q5ZM44,Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22),Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22),GO:0000139; GO:0005509; GO:0048306; GO:0071468; GO:0031122; GO:0005783; GO:0005793; GO:0019900; GO:0022406; GO:0061025; GO:0008017; GO:0001578; GO:0015630; GO:0032088; GO:0070885; GO:0010923; GO:0031953; GO:0042308; GO:0006469; GO:0031397; GO:0005634; GO:0005886; GO:0060050; GO:0090314; GO:0032417; GO:0006611; GO:0004860; GO:0050821; GO:0051453; GO:0030133; GO:0005215,Golgi membrane; calcium ion binding; calcium-dependent protein binding; cellular response to acidity; cytoplasmic microtubule organization; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; kinase binding; membrane docking; membrane fusion; microtubule binding; microtubule bundle formation; microtubule cytoskeleton; negative regulation of NF-kappaB transcription factor activity; negative regulation of calcineurin-NFAT signaling cascade; negative regulation of phosphatase activity; negative regulation of protein autophosphorylation; negative regulation of protein import into nucleus; negative regulation of protein kinase activity; negative regulation of protein ubiquitination; nucleus; plasma membrane; positive regulation of protein glycosylation; positive regulation of protein targeting to membrane; positive regulation of sodium:hydrogen antiporter activity; protein export from nucleus; protein kinase inhibitor activity; protein stabilization; regulation of intracellular pH; transport vesicle; transporter activity,PF13499;,2.00E-50,CHOYP_CHP1.1.2,,,,,,,CHP1_CHICK,Gallus gallus (Chicken),cellular response to acidic pH [GO:0071468]; cytoplasmic microtubule organization [GO:0031122]; membrane docking [GO:0022406]; membrane fusion [GO:0061025]; membrane organization [GO:0061024]; microtubule bundle formation [GO:0001578]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein glycosylation [GO:0060050]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein transport [GO:0051222]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein export from nucleus [GO:0006611]; protein stabilization [GO:0050821]; regulation of intracellular pH [GO:0051453]; regulation of neuron death [GO:1901214] comp124308_c0_seq1,202,44.5545,0.50223893,7,18,,1.00E-22,B4GY79,Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109),Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109),GO:0019284; GO:0019509; GO:0005737; GO:0046570; GO:0008270,L-methionine biosynthetic process from S-adenosylmethionine; L-methionine salvage from methylthioadenosine; cytoplasm; methylthioribulose 1-phosphate dehydratase activity; zinc ion binding,PF00596;,,,,,,,,,MTNB_DROPE,Drosophila persimilis (Fruit fly),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp124308_c2_seq1,814,38.8206,0.26542948,4,6,,6.00E-11,Q6FJA5,Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109),Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109),GO:0019284; GO:0019509; GO:0005737; GO:0046570; GO:0008270,L-methionine biosynthetic process from S-adenosylmethionine; L-methionine salvage from methylthioadenosine; cytoplasm; methylthioribulose 1-phosphate dehydratase activity; zinc ion binding,PF00596;,,,,,,,,,MTNB_CANGA,Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp124308_c2_seq2,730,39.726,0.28300479,0,0,,1.00E-49,C1C4M8,Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog),Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog),GO:0019284; GO:0019509; GO:0006915; GO:0005737; GO:0046570; GO:0008270,L-methionine biosynthetic process from S-adenosylmethionine; L-methionine salvage from methylthioadenosine; apoptotic process; cytoplasm; methylthioribulose 1-phosphate dehydratase activity; zinc ion binding,PF00596;,8.00E-54,CHOYP_MTNB.1.1,,,,,,,MTNB_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),apoptotic process [GO:0006915]; L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp124318_c0_seq1,621,46.5378,0.49073106,31,27,,5.00E-88,Q56UN5,"Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)","Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)",GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,9.00E-116,CHOYP_LOC100374274.3.3,,,,,,,YSK4_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036] comp124331_c0_seq2,628,40.9236,0.6277461,10,68,,7.00E-17,Q8TDH9,Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog),Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog),GO:0031083; GO:0008089; GO:0048490; GO:0035646; GO:0032438; GO:0032402; GO:0031175; GO:0032474; GO:0050942; GO:0030133,BLOC-1 complex; anterograde axon cargo transport; anterograde synaptic vesicle transport; endosome to melanosome transport; melanosome organization; melanosome transport; neuron projection development; otolith morphogenesis; positive regulation of pigment cell differentiation; transport vesicle,PF14942;,,,,,,,,,MUTED_HUMAN,Homo sapiens (Human),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosome to melanosome transport [GO:0035646]; melanosome organization [GO:0032438]; melanosome transport [GO:0032402]; neuron projection development [GO:0031175]; positive regulation of pigment cell differentiation [GO:0050942] comp124335_c0_seq3,711,40.3657,1.07187469,0,56,,8.00E-17,Q16706,"Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0006491; GO:0030246; GO:0016799; GO:0001701; GO:0016021; GO:0001889; GO:0048286; GO:0006013; GO:0004572; GO:0007005; GO:0043687; GO:0018279; GO:0007585; GO:0007033; GO:0008270,"Golgi membrane; N-glycan processing; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; in utero embryonic development; integral to membrane; liver development; lung alveolus development; mannose metabolic process; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; mitochondrion organization; post-translational protein modification; protein N-linked glycosylation via asparagine; respiratory gaseous exchange; vacuole organization; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A1_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033] comp124337_c0_seq1,910,37.6923,0.35422454,21,83,,2.00E-19,Q9D9B4,Leucine-rich repeat-containing protein C10orf11 homolog,Leucine-rich repeat-containing protein C10orf11 homolog,GO:0030318,melanocyte differentiation,,7.00E-24,CHOYP_NEMVEDRAFT_V1G185153.1.1,1.00E-43,ruditapes_c16926,,,,,CJ011_MOUSE,Mus musculus (Mouse),melanocyte differentiation [GO:0030318] comp124340_c0_seq1,936,42.094,0.94221952,272,1084,,1.00E-75,O75884,Putative hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9),Putative hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9),GO:0005737; GO:0016787; GO:0005634; GO:0042127,cytoplasm; hydrolase activity; nucleus; regulation of cell proliferation,PF06821;,2.00E-55,CHOYP_BRAFLDRAFT_277797.1.1,5.00E-75,ruditapes_c29881,,,,,RBBP9_HUMAN,Homo sapiens (Human),regulation of cell proliferation [GO:0042127] comp124341_c0_seq2,1109,42.11,0.52961946,3,0,,8.00E-35,Q9ESJ4,NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein),NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein),GO:0008180,COP9 signalosome,PF09431;PF00018;,1.00E-10,CHOYP_LOC100374747.1.1,,,,,,,SPN90_MOUSE,Mus musculus (Mouse),positive regulation of neuron projection development [GO:0010976] comp124341_c1_seq3,532,41.3534,0.55062178,8,0,,7.00E-34,Q9ESJ4,NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein),NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein),GO:0008180,COP9 signalosome,PF09431;PF00018;,,,,,,,,,SPN90_MOUSE,Mus musculus (Mouse),positive regulation of neuron projection development [GO:0010976] comp124348_c0_seq1,1868,46.1456,0.35251809,10,14,,3.00E-57,Q9NZ56,Formin-2,Formin-2,GO:0003779; GO:0005938; GO:0071456; GO:0030659; GO:0005856; GO:0005829; GO:0051295; GO:0070649; GO:0051758; GO:0035556; GO:0046907; GO:0007275; GO:0043066; GO:0042177; GO:0005730; GO:0048477; GO:0048471; GO:0005886; GO:0040038; GO:0015031; GO:0006974; GO:0016192,actin binding; cell cortex; cellular response to hypoxia; cytoplasmic vesicle membrane; cytoskeleton; cytosol; establishment of meiotic spindle localization; formin-nucleated actin cable assembly; homologous chromosome movement towards spindle pole involved in homologous chromosome segregation; intracellular signal transduction; intracellular transport; multicellular organismal development; negative regulation of apoptotic process; negative regulation of protein catabolic process; nucleolus; oogenesis; perinuclear region of cytoplasm; plasma membrane; polar body extrusion after meiotic divisions; protein transport; response to DNA damage stimulus; vesicle-mediated transport,PF06346;PF02181;,2.00E-34,CHOYP_FMN2.1.1,,,,,,,FMN2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; homologous chromosome movement towards spindle pole involved in homologous chromosome segregation [GO:0051758]; intracellular signal transduction [GO:0035556]; intracellular transport [GO:0046907]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp124348_c0_seq4,1312,49.6951,0.33448461,0,0,,4.00E-09,Q68DA7,Formin-1 (Limb deformity protein homolog),Formin-1 (Limb deformity protein homolog),GO:0003677; GO:0005884; GO:0045010; GO:0005912; GO:0005737; GO:0035136; GO:0010467; GO:0035137; GO:0005634; GO:0005886; GO:0051127; GO:0048705,DNA binding; actin filament; actin nucleation; adherens junction; cytoplasm; forelimb morphogenesis; gene expression; hindlimb morphogenesis; nucleus; plasma membrane; positive regulation of actin nucleation; skeletal system morphogenesis,PF02181;,9.00E-25,CHOYP_AGO2.1.1,,,,,,,FMN1_HUMAN,Homo sapiens (Human),actin nucleation [GO:0045010]; dendrite morphogenesis [GO:0048813]; forelimb morphogenesis [GO:0035136]; gene expression [GO:0010467]; hindlimb morphogenesis [GO:0035137]; positive regulation of actin nucleation [GO:0051127]; positive regulation of focal adhesion assembly [GO:0051894]; skeletal system morphogenesis [GO:0048705]; ureteric bud invasion [GO:0072092] comp124354_c0_seq1,1201,42.8809,0.52580964,120,62,,1.00E-50,O35738,Krueppel-like factor 12 (Transcriptional repressor AP-2rep),Krueppel-like factor 12 (Transcriptional repressor AP-2rep),GO:0000977; GO:0001227; GO:0046872; GO:0005634; GO:0045944,RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter,PF00096;,1.00E-54,CHOYP_LOC660309.2.2,,,,,,,KLF12_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124356_c0_seq1,807,39.5291,0.41504726,121,1636,,4.00E-18,Q3U6N9,UPF0488 protein C8orf33 homolog,UPF0488 protein C8orf33 homolog,,,PF15393;,,,,,,,,,CH033_MOUSE,Mus musculus (Mouse), comp124359_c0_seq1,1501,47.6349,0.53298555,0,0,,1.00E-92,Q9QW30,Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],GO:0007219; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0005829; GO:0005576; GO:0005887; GO:0008285; GO:0005634; GO:0009887; GO:0046579; GO:0004872; GO:0050793; GO:0006355; GO:0042246; GO:0006351,"Notch signaling pathway; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; cytosol; extracellular region; integral to plasma membrane; negative regulation of cell proliferation; nucleus; organ morphogenesis; positive regulation of Ras protein signal transduction; receptor activity; regulation of developmental process; regulation of transcription, DNA-dependent; tissue regeneration; transcription, DNA-dependent",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,6.00E-78,CHOYP_LOC100897243.1.1,,,,,,,NOTC2_RAT,Rattus norvegicus (Rat),"cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; marginal zone B cell differentiation [GO:0002315]; negative regulation of cell proliferation [GO:0008285]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; tissue regeneration [GO:0042246]; transcription, DNA-templated [GO:0006351]" comp124359_c0_seq2,1868,47.6445,0.58141473,21,33,,7.00E-124,Q9R172,Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain],Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain],GO:0007219; GO:0005509; GO:0030154; GO:0016021; GO:0007275; GO:0005634; GO:0005886; GO:0050793; GO:0006355; GO:0042246; GO:0006351,"Notch signaling pathway; calcium ion binding; cell differentiation; integral to membrane; multicellular organismal development; nucleus; plasma membrane; regulation of developmental process; regulation of transcription, DNA-dependent; tissue regeneration; transcription, DNA-dependent",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTC3_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; Notch signaling pathway [GO:0007219]; regulation of transcription, DNA-templated [GO:0006355]; tissue regeneration [GO:0042246]; transcription, DNA-templated [GO:0006351]" comp124359_c1_seq1,792,47.601,0.54028361,25,38,,2.00E-57,P49013,Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),GO:0005509; GO:0005615,calcium ion binding; extracellular space,PF01382;PF00431;PF00008;,,,,,,,,,FBP3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp124364_c1_seq1,1385,41.1552,0.5133336,79,59,,4.00E-84,A6QP16,Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1),Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1),GO:0016055; GO:0016477; GO:0005737; GO:0007010; GO:0005634; GO:0030177; GO:0035523; GO:1990168; GO:0070536; GO:0071947; GO:0022604; GO:0004221; GO:0004843; GO:0008270,Wnt receptor signaling pathway; cell migration; cytoplasm; cytoskeleton organization; nucleus; positive regulation of Wnt receptor signaling pathway; protein K29-linked deubiquitination; protein K33-linked deubiquitination; protein K63-linked deubiquitination; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of cell morphogenesis; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding,PF02338;PF00641;,7.00E-20,CHOYP_ZRN1B.1.1,,,,,,,ZRAN1_BOVIN,Bos taurus (Bovine),cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] comp124364_c2_seq1,751,48.0692,0.23300531,19,13,,2.00E-87,Q9VH90,Ubiquitin thioesterase trabid (dTrbd) (EC 3.4.19.12),Ubiquitin thioesterase trabid (dTrbd) (EC 3.4.19.12),GO:0016055; GO:0008234; GO:0030177; GO:0070536; GO:0006508; GO:0004221; GO:0008270,Wnt receptor signaling pathway; cysteine-type peptidase activity; positive regulation of Wnt receptor signaling pathway; protein K63-linked deubiquitination; proteolysis; ubiquitin thiolesterase activity; zinc ion binding,PF02338;PF00641;,3.00E-46,CHOYP_ZRN1B.1.1,,,,,,,TRBID_DROME,Drosophila melanogaster (Fruit fly),cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; Wnt signaling pathway [GO:0016055] comp124370_c0_seq2,750,45.4667,0.41463152,22,71,,,,,,,,,8.00E-16,CHOYP_SRR-2.1.1,,,,,,,,, comp124371_c0_seq1,778,26.9923,0.50009254,8,7,,5.00E-20,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp124371_c0_seq3,564,26.5957,0.40436699,0,0,,9.00E-19,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,7.00E-26,ruditapes_c19911,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp124380_c1_seq1,492,45.3252,0.67807723,2,71,,2.00E-47,Q640L2,Sugar phosphate exchanger 3 (Solute carrier family 37 member 3),Sugar phosphate exchanger 3 (Solute carrier family 37 member 3),GO:0008643; GO:0016021; GO:0055085; GO:0005215,carbohydrate transport; integral to membrane; transmembrane transport; transporter activity,PF07690;,1.00E-30,CHOYP_SPX3.1.1,,,,,,,SPX3_XENLA,Xenopus laevis (African clawed frog),carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085] comp124382_c1_seq1,652,49.8466,0.74221589,24,43,,4.00E-65,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp124385_c0_seq1,1867,37.0648,0.31476435,91,628,,4.00E-09,Q9UPN9,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0030514; GO:0000122; GO:0005654; GO:0017015; GO:0006367; GO:0007179; GO:0004842; GO:0008270,DNA binding; negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; regulation of transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_HUMAN,Homo sapiens (Human),"negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]" comp124392_c0_seq1,819,40.9035,1.05293351,16,153,,1.00E-17,O57321,Excitatory amino acid transporter 1 (SEAAT1),Excitatory amino acid transporter 1 (SEAAT1),GO:0016021; GO:0017153,integral to membrane; sodium:dicarboxylate symporter activity,PF00375;,,,,,,,,,EAA1_AMBTI,Ambystoma tigrinum (Eastern tiger salamander), comp124392_c0_seq2,610,42.7869,0.75396841,7,58,,5.00E-30,P51906,Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1),Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1),GO:0070779; GO:0051938; GO:0016595; GO:0015501; GO:0016021; GO:0005886; GO:0051260; GO:0017153,D-aspartate import; L-glutamate import; glutamate binding; glutamate:sodium symporter activity; integral to membrane; plasma membrane; protein homooligomerization; sodium:dicarboxylate symporter activity,PF00375;,,,,,,,,,EAA3_MOUSE,Mus musculus (Mouse),cysteine transport [GO:0042883]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260] comp124402_c0_seq1,1132,34.894,0.32897819,68,78,,,,,,,,,8.00E-12,CHOYP_MGA.2.2,,,,,,,,, comp124410_c0_seq1,696,46.8391,0.50459239,69,45,,3.00E-105,Q26626,Kinesin-associated protein 3 (SpKAP115),Kinesin-associated protein 3 (SpKAP115),GO:0016939; GO:0007017,kinesin II complex; microtubule-based process,,1.00E-108,CHOYP_LOC100371756.1.1,,,,,,,KIFA3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),microtubule-based process [GO:0007017] comp124411_c0_seq1,1066,38.743,0.63408168,44,92,,4.00E-16,P61268,Syntaxin-1B (Syntaxin-1B2),Syntaxin-1B (Syntaxin-1B2),GO:0016021; GO:0006886; GO:0006836; GO:0016192,integral to membrane; intracellular protein transport; neurotransmitter transport; vesicle-mediated transport,PF05739;PF00804;,,,,,,,,,STX1B_SHEEP,Ovis aries (Sheep),intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter transport [GO:0006836]; regulation of exocytosis [GO:0017157]; vesicle-mediated transport [GO:0016192] comp124412_c0_seq1,1061,42.8841,0.98496822,0,22,,2.00E-56,Q8CHI9,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; hexose biosynthetic process; integral to membrane,,,,,,,,,,CHSTF_RAT,Rattus norvegicus (Rat),hexose biosynthetic process [GO:0019319] comp124413_c1_seq1,929,41.9806,0.98267231,0,166,,2.00E-29,Q7M370,Arylacetamide deacetylase (EC 3.1.1.3) (50 kDa microsomal esterase/N-deacetylase),Arylacetamide deacetylase (EC 3.1.1.3) (50 kDa microsomal esterase/N-deacetylase),GO:0004091; GO:0019213; GO:0005789; GO:0016021; GO:0004806,carboxylesterase activity; deacetylase activity; endoplasmic reticulum membrane; integral to membrane; triglyceride lipase activity,PF07859;,8.00E-11,CHOYP_AADACL4.1.1,2.00E-17,ruditapes_c18889,,,,,AAAD_RABIT,Oryctolagus cuniculus (Rabbit),metabolic process [GO:0008152] comp124441_c0_seq3,1057,42.7625,0.56415573,0,0,,4.00E-24,Q6PIJ6,F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA),F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00646;,,,,,,,,,FBX38_HUMAN,Homo sapiens (Human),positive regulation of neuron projection development [GO:0010976] comp124454_c0_seq1,249,45.7831,0.85061687,1,24,,1.00E-16,Q9NPD5,Solute carrier organic anion transporter family member 1B3 (Liver-specific organic anion transporter 2) (LST-2) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP-8) (Solute carrier family 21 member 8),Solute carrier organic anion transporter family member 1B3 (Liver-specific organic anion transporter 2) (LST-2) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP-8) (Solute carrier family 21 member 8),GO:0016323; GO:0015721; GO:0008206; GO:0005737; GO:0005887; GO:0008514; GO:0043252,basolateral plasma membrane; bile acid and bile salt transport; bile acid metabolic process; cytoplasm; integral to plasma membrane; organic anion transmembrane transporter activity; sodium-independent organic anion transport,PF07648;PF03137;,,,,,,,,,SO1B3_HUMAN,Homo sapiens (Human),bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252] comp124455_c0_seq1,2662,40.6461,0.409754,9,4394,female>male,6.00E-19,Q9NYQ7,Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,6.00E-12,CHOYP_LOC100636493.1.1,,,,,,,CELR3_HUMAN,Homo sapiens (Human),"axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp124455_c1_seq1,1044,38.1226,0.60768159,1,189,,3.00E-22,Q9HCU4,Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),GO:0004930; GO:0016055; GO:0005509; GO:0033326; GO:0042384; GO:0003341; GO:0005737; GO:0048813; GO:0007156; GO:0016021; GO:0021999; GO:0001764; GO:0007218; GO:0005886; GO:0022407; GO:0032880; GO:0006355; GO:0021591,"G-protein coupled receptor activity; Wnt receptor signaling pathway; calcium ion binding; cerebrospinal fluid secretion; cilium assembly; cilium movement; cytoplasm; dendrite morphogenesis; homophilic cell adhesion; integral to membrane; neural plate anterior/posterior regionalization; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of cell-cell adhesion; regulation of protein localization; regulation of transcription, DNA-dependent; ventricular system development",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR2_HUMAN,Homo sapiens (Human),"dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp124459_c0_seq1,2598,35.4888,0.7585786,652,5114,,4.00E-38,Q06831,Transcription factor SOX-4,Transcription factor SOX-4,GO:0042769; GO:0006977; GO:0001077; GO:0001105; GO:0030217; GO:0035910; GO:0003289; GO:0060070; GO:0003215; GO:0003211; GO:0071333; GO:0001046; GO:0031018; GO:0021782; GO:0014009; GO:0060993; GO:0060174; GO:0005739; GO:0003183; GO:0060548; GO:0008285; GO:0046826; GO:0031397; GO:0001841; GO:0060563; GO:0003357; GO:0044798; GO:2000761; GO:0043065; GO:0090263; GO:0008284; GO:0032024; GO:0045727; GO:0002328; GO:0046982; GO:0050821; GO:0001501; GO:0035019; GO:0021522; GO:0048485; GO:0060412,"DNA damage response, detection of DNA damage; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription coactivator activity; T cell differentiation; ascending aorta morphogenesis; atrial septum primum morphogenesis; canonical Wnt receptor signaling pathway; cardiac right ventricle morphogenesis; cardiac ventricle formation; cellular response to glucose stimulus; core promoter sequence-specific DNA binding; endocrine pancreas development; glial cell development; glial cell proliferation; kidney morphogenesis; limb bud formation; mitochondrion; mitral valve morphogenesis; negative regulation of cell death; negative regulation of cell proliferation; negative regulation of protein export from nucleus; negative regulation of protein ubiquitination; neural tube formation; neuroepithelial cell differentiation; noradrenergic neuron differentiation; nuclear transcription factor complex; positive regulation of N-terminal peptidyl-lysine acetylation; positive regulation of apoptotic process; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell proliferation; positive regulation of insulin secretion; positive regulation of translation; pro-B cell differentiation; protein heterodimerization activity; protein stabilization; skeletal system development; somatic stem cell maintenance; spinal cord motor neuron differentiation; sympathetic nervous system development; ventricular septum morphogenesis",PF00505;,1.00E-63,CHOYP_ISCW_ISCW015396.1.1,,,,,,,SOX4_MOUSE,Mus musculus (Mouse),"ascending aorta morphogenesis [GO:0035910]; atrial septum primum morphogenesis [GO:0003289]; canonical Wnt signaling pathway [GO:0060070]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac ventricle formation [GO:0003211]; cellular response to glucose stimulus [GO:0071333]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocrine pancreas development [GO:0031018]; glial cell development [GO:0021782]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; kidney morphogenesis [GO:0060993]; limb bud formation [GO:0060174]; mitral valve morphogenesis [GO:0003183]; negative regulation of cell death [GO:0060548]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein ubiquitination [GO:0031397]; neural tube formation [GO:0001841]; neuroepithelial cell differentiation [GO:0060563]; noradrenergic neuron differentiation [GO:0003357]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of insulin secretion [GO:0032024]; positive regulation of N-terminal peptidyl-lysine acetylation [GO:2000761]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of Wnt signaling pathway [GO:0030177]; pro-B cell differentiation [GO:0002328]; protein stabilization [GO:0050821]; regulation of protein stability [GO:0031647]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]; somatic stem cell population maintenance [GO:0035019]; spinal cord development [GO:0021510]; spinal cord motor neuron differentiation [GO:0021522]; sympathetic nervous system development [GO:0048485]; T cell differentiation [GO:0030217]; ventricular septum morphogenesis [GO:0060412]" comp124462_c0_seq1,564,42.7305,0.61825406,65,11,,2.00E-28,Q96Q15,Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (61E3.4) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein),Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (61E3.4) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein),GO:0005524; GO:0006281; GO:0005829; GO:0010467; GO:0006406; GO:0046872; GO:0000184; GO:0005634; GO:0018105; GO:0046854; GO:0046777; GO:0004674; GO:0006950,"ATP binding; DNA repair; cytosol; gene expression; mRNA export from nucleus; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; phosphatidylinositol phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity; response to stress",PF02260;PF00454;PF15785;,2.00E-40,CHOYP_SMG1.1.1,,,,,,,SMG1_HUMAN,Homo sapiens (Human),"DNA repair [GO:0006281]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; response to stress [GO:0006950]; telomere maintenance [GO:0000723]" comp124468_c0_seq1,910,40.8791,0.5034546,48,102,,4.00E-135,Q6TUG0,DnaJ homolog subfamily B member 11 (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (Liver regeneration-related protein LRRGT00084),DnaJ homolog subfamily B member 11 (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (Liver regeneration-related protein LRRGT00084),GO:0005788; GO:0016556; GO:0005634; GO:0006457,endoplasmic reticulum lumen; mRNA modification; nucleus; protein folding,PF00226;PF01556;,2.00E-150,CHOYP_LOC588440.1.1,,,,,,,DJB11_RAT,Rattus norvegicus (Rat),mRNA modification [GO:0016556]; positive regulation of ATPase activity [GO:0032781]; protein folding [GO:0006457] comp124472_c0_seq1,821,40.5603,0.45381002,553,2461,,5.00E-45,Q2T9Y1,Uncharacterized protein C3orf26 homolog,Uncharacterized protein C3orf26 homolog,,,PF14617;,1.00E-21,CHOYP_CC026.1.1,1.00E-50,ruditapes_c24188,,,,,CC026_BOVIN,Bos taurus (Bovine), comp124473_c0_seq1,892,42.0404,0.81538652,0,15,,4.00E-08,P46499,Uncharacterized protein F23F12.3,Uncharacterized protein F23F12.3,GO:0016021; GO:0022857,integral to membrane; transmembrane transporter activity,PF00083;,,,,,,,,,YLX3_CAEEL,Caenorhabditis elegans, comp124473_c0_seq2,975,42.5641,0.93395048,0,26,,5.00E-16,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp124474_c0_seq1,1455,39.9313,0.9030754,49,291,,9.00E-16,P69478,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),GO:0000139; GO:0001537; GO:0050659; GO:0016051; GO:0002063; GO:0047756; GO:0030206; GO:0048589; GO:0042733; GO:0048703; GO:0016021; GO:0043066; GO:0030512; GO:0033037; GO:0036342; GO:0009791; GO:0042127; GO:0007585,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; carbohydrate biosynthetic process; chondrocyte development; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; developmental growth; embryonic digit morphogenesis; embryonic viscerocranium morphogenesis; integral to membrane; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; polysaccharide localization; post-anal tail morphogenesis; post-embryonic development; regulation of cell proliferation; respiratory gaseous exchange,PF03567;,,,,,,,,,CHSTB_RAT,Rattus norvegicus (Rat),carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585] comp124476_c0_seq1,736,41.1685,0.66092849,49,31,,5.00E-16,P11475,Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2),Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2),GO:0000980; GO:0005634; GO:0045944; GO:0043565; GO:0003700; GO:0005496; GO:0003707; GO:0003713; GO:0006351; GO:0008270,"RNA polymerase II distal enhancer sequence-specific DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; transcription coactivator activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,1.00E-14,CHOYP_NR2.1.1,,,,,,,ERR2_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124481_c0_seq1,437,47.5973,0.62619466,6,65,,5.00E-45,Q3UHK1,Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),GO:0016021; GO:0022891,integral to membrane; substrate-specific transmembrane transporter activity,PF00083;,,,,,,,,,MYCT_MOUSE,Mus musculus (Mouse),glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428] comp124483_c0_seq1,617,47.1637,0.52650649,9,13,,,,,,,,,2.00E-61,CHOYP_ALG9.1.1,,,,,,,,, comp124483_c1_seq1,1543,39.987,0.37407844,31,136,,5.00E-140,Q8VDI9,"Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1 homolog) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)","Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1 homolog) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)",GO:0052926; GO:0052918; GO:0005789; GO:0016021; GO:0006486,"dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity; dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; protein glycosylation",PF03901;,,,,,,,,,ALG9_MOUSE,Mus musculus (Mouse),protein glycosylation [GO:0006486] comp124483_c1_seq2,543,34.6225,0.55409876,0,0,,,,,,,,,3.00E-13,CHOYP_ALG9.1.1,,,,,,,,, comp124485_c0_seq1,650,43.8462,0.94235024,8,142,,1.00E-39,Q8JIS3,D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),GO:0042732; GO:0050038; GO:0005737; GO:0047880,D-xylose metabolic process; L-xylulose reductase (NADP+) activity; cytoplasm; erythrulose reductase activity,,,,,,,,,,DER_CHICK,Gallus gallus (Chicken),D-xylose metabolic process [GO:0042732] comp124488_c0_seq1,271,48.3395,1.07937978,29,19,,3.00E-07,P21331,Nucleic-acid-binding protein from mobile element jockey (ORF1),Nucleic-acid-binding protein from mobile element jockey (ORF1),GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,PF07530;,,,,,,,,,GAGJ_DROFU,Drosophila funebris (Fruit fly), comp124491_c0_seq1,857,47.7246,0.83467208,37,51,,9.00E-08,Q8IVL1,Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2),Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2),GO:0005524; GO:0021563; GO:0004386; GO:0008201; GO:0005614; GO:0007626; GO:0005634; GO:0021554; GO:0003025; GO:0007608; GO:0007605; GO:0021564,ATP binding; glossopharyngeal nerve development; helicase activity; heparin binding; interstitial matrix; locomotory behavior; nucleus; optic nerve development; regulation of systemic arterial blood pressure by baroreceptor feedback; sensory perception of smell; sensory perception of sound; vagus nerve development,PF00307;,3.00E-54,CHOYP_NAV2.2.3,7.00E-28,ruditapes_c30755,,,,,NAV2_HUMAN,Homo sapiens (Human),glossopharyngeal nerve development [GO:0021563]; locomotory behavior [GO:0007626]; optic nerve development [GO:0021554]; regulation of systemic arterial blood pressure by baroreceptor feedback [GO:0003025]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; vagus nerve development [GO:0021564] comp124504_c0_seq1,542,43.7269,0.39745414,0,0,,5.00E-16,Q97EZ6,Galactokinase (EC 2.7.1.6) (Galactose kinase),Galactokinase (EC 2.7.1.6) (Galactose kinase),GO:0005524; GO:0005737; GO:0004335; GO:0006012; GO:0000287,ATP binding; cytoplasm; galactokinase activity; galactose metabolic process; magnesium ion binding,PF10509;PF08544;PF00288;,,,,,,,,,GAL1_CLOAB,Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787),galactose metabolic process [GO:0006012] comp124504_c0_seq2,1272,43.1604,0.20954745,23,70,,7.00E-128,Q01415,N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2),N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2),GO:0005524; GO:0033858; GO:0005737; GO:0004335; GO:0006012,ATP binding; N-acetylgalactosamine kinase activity; cytoplasm; galactokinase activity; galactose metabolic process,PF10509;PF08544;PF00288;,8.00E-57,CHOYP_GALK2.1.2,,,,,,,GALK2_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; galactose metabolic process [GO:0006012] comp124506_c0_seq1,436,41.055,0.29898898,8,25,,7.00E-23,Q92738,USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre),USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre),GO:0005794; GO:0007030; GO:0005097; GO:0016023; GO:0031410; GO:0035526,"Golgi apparatus; Golgi organization; Rab GTPase activator activity; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; retrograde transport, plasma membrane to Golgi",PF00566;,3.00E-18,CHOYP_PHUM_PHUM537100.1.1,,,,,,,US6NL_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; regulation of Golgi organization [GO:1903358]; regulation of vesicle fusion [GO:0031338]; retrograde transport, plasma membrane to Golgi [GO:0035526]; virion assembly [GO:0019068]" comp124507_c1_seq1,427,44.2623,0.63807689,10,0,,5.00E-25,Q8BWR4,Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP40_MOUSE,Mus musculus (Mouse),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp124507_c2_seq1,285,44.2105,0.23315504,5,9,,6.00E-28,Q9NVE5,Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,9.00E-23,CHOYP_LOC577573.1.1,,,,,,,UBP40_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp124511_c0_seq1,1124,45.4626,0.31221116,54,3,,1.00E-17,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,,,2.00E-29,ruditapes_c21198,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp124513_c0_seq1,1427,35.5992,0.51729377,7,528,,,,,,,,,6.00E-21,CHOYP_PBX4.2.2,,,,,,,,, comp124515_c1_seq1,1103,46.7815,0.51422174,36,58,,7.00E-122,A2VDL9,Transmembrane protein 184B,Transmembrane protein 184B,GO:0016021,integral to membrane,PF03619;,2.00E-171,CHOYP_T184B.1.1,,,,,,,T184B_BOVIN,Bos taurus (Bovine),transport [GO:0006810] comp124516_c0_seq4,944,32.4153,0.36684824,0,0,,2.00E-06,Q8BX22,Sal-like protein 4 (Zinc finger protein SALL4),Sal-like protein 4 (Zinc finger protein SALL4),GO:0003677; GO:0005737; GO:0030326; GO:0000792; GO:0001833; GO:0046872; GO:0000122; GO:0001843; GO:0005634; GO:0045944; GO:0019827; GO:0005667; GO:0006351; GO:0003281,"DNA binding; cytoplasm; embryonic limb morphogenesis; heterochromatin; inner cell mass cell proliferation; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance; transcription factor complex; transcription, DNA-dependent; ventricular septum development",PF00096;,,,,,,,,,SALL4_MOUSE,Mus musculus (Mouse),"embryonic limb morphogenesis [GO:0030326]; heart development [GO:0007507]; inner cell mass cell proliferation [GO:0001833]; in utero embryonic development [GO:0001701]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]; stem cell population maintenance [GO:0019827]; tissue development [GO:0009888]; transcription, DNA-templated [GO:0006351]; ventricular septum development [GO:0003281]" comp124532_c1_seq1,879,41.6382,0.29127712,22,31,,7.00E-76,Q9Y6X3,MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog),MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog),GO:0032116; GO:0051301; GO:0000785; GO:0034088; GO:0005654,SMC loading complex; cell division; chromatin; maintenance of mitotic sister chromatid cohesion; nucleoplasm,PF10345;,1.00E-65,CHOYP_LOC411194.1.1,,,,,,,SCC4_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; maintenance of mitotic sister chromatid cohesion [GO:0034088] comp124532_c2_seq1,262,37.0229,0.79286254,8,10,,6.00E-09,O17581,Maternal uncoordinated protein 2 (Cohesin loading complex subunit SCC4 homolog),Maternal uncoordinated protein 2 (Cohesin loading complex subunit SCC4 homolog),GO:0032116; GO:0033564; GO:0030424; GO:0051301; GO:0000785; GO:0005737; GO:0033563; GO:0034088; GO:0005654; GO:0018991,SMC loading complex; anterior/posterior axon guidance; axon; cell division; chromatin; cytoplasm; dorsal/ventral axon guidance; maintenance of mitotic sister chromatid cohesion; nucleoplasm; oviposition,,,,,,,,,,SCC4_CAEEL,Caenorhabditis elegans,anterior/posterior axon guidance [GO:0033564]; cell division [GO:0051301]; dorsal/ventral axon guidance [GO:0033563]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; oviposition [GO:0018991] comp124536_c0_seq1,1251,43.5651,0.44138333,41,67,,9.00E-86,Q75V66,Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E),Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E),GO:0005789; GO:0016021; GO:0005622; GO:0034220; GO:0005886,endoplasmic reticulum membrane; integral to membrane; intracellular; ion transmembrane transport; plasma membrane,PF16178;PF04547;,1.00E-118,CHOYP_AAEL_AAEL006656.1.1,,,,,,,ANO5_HUMAN,Homo sapiens (Human),chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220] comp124536_c0_seq2,464,38.1466,0.18302368,2,0,,2.00E-07,A0MFS9,Anoctamin-like protein At1g73020,Anoctamin-like protein At1g73020,GO:0005254; GO:0034707,chloride channel activity; chloride channel complex,PF04547;,,,,,,,,,CACLC_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp124547_c0_seq2,1166,40.3945,1.2085583,17,232,,2.00E-75,A0MGZ7,Heparan-sulfate 6-O-sulfotransferase 3 (HS 6-OST-3) (EC 2.8.2.-),Heparan-sulfate 6-O-sulfotransferase 3 (HS 6-OST-3) (EC 2.8.2.-),GO:0016021; GO:0008146,integral to membrane; sulfotransferase activity,PF03567;,,,,,,,,,H6ST3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" comp12454_c0_seq1,240,47.9167,0.14632919,4,0,,2.00E-30,O95427,GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GO:0006501; GO:0005789; GO:0016021; GO:0016254; GO:0016740,C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane; transferase activity,PF01663;PF04987;,,,,,,,,,PIGN_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp124558_c1_seq1,476,43.2773,0.61806313,19,46,,1.00E-10,Q9Y6N9,Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein),Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein),GO:0000086; GO:0045177; GO:0042491; GO:0005737; GO:0005856; GO:0005829; GO:0050957; GO:0042472; GO:0030046; GO:0045494; GO:0001917; GO:0001750; GO:0005886; GO:0050953; GO:0007605; GO:0032420; GO:0045202,G2/M transition of mitotic cell cycle; apical part of cell; auditory receptor cell differentiation; cytoplasm; cytoskeleton; cytosol; equilibrioception; inner ear morphogenesis; parallel actin filament bundle assembly; photoreceptor cell maintenance; photoreceptor inner segment; photoreceptor outer segment; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilium; synapse,PF00595;,,,,,,,,,USH1C_HUMAN,Homo sapiens (Human),brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; cellular protein complex assembly [GO:0043623]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] comp124562_c0_seq1,695,41.295,1.18413623,15,46,,6.00E-43,Q9CZR2,N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II),N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II),GO:0050129; GO:0004180; GO:0016805; GO:0016021; GO:0046872; GO:0008237; GO:0042135; GO:0006508,N-formylglutamate deformylase activity; carboxypeptidase activity; dipeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; neurotransmitter catabolic process; proteolysis,PF02225;PF04389;PF04253;,,,,,,,,,NALD2_MOUSE,Mus musculus (Mouse),neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] comp124565_c0_seq1,256,44.1406,0.48613604,6,7,,1.00E-11,Q5U1Z0,Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0030234; GO:0005886; GO:0043547,GTPase activator activity; cytoplasm; enzyme regulator activity; plasma membrane; positive regulation of GTPase activity,PF14656;PF14655;,,,,,,,,,RBGPR_RAT,Rattus norvegicus (Rat),positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp124568_c0_seq1,1183,39.3068,0.48197799,38,196,,6.00E-13,P70587,Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1),Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1),GO:0043194; GO:0030054; GO:0005737; GO:0043197; GO:0030175; GO:0005886; GO:0010976; GO:0014069; GO:0045211; GO:0008022; GO:0014070,axon initial segment; cell junction; cytoplasm; dendritic spine; filopodium; plasma membrane; positive regulation of neuron projection development; postsynaptic density; postsynaptic membrane; protein C-terminus binding; response to organic cyclic compound,PF13855;PF00595;,,,,,,,,,LRRC7_RAT,Rattus norvegicus (Rat),positive regulation of neuron projection development [GO:0010976]; response to organic cyclic compound [GO:0014070] comp124572_c0_seq1,644,47.205,0.50681107,41,17,,2.00E-11,Q8BLN6,Protein unc-80 homolog (mUNC-80),Protein unc-80 homolog (mUNC-80),GO:0016021,integral to membrane,PF15778;,1.00E-26,CHOYP_PHUM_PHUM244880.1.2,,,,,,,UNC80_MOUSE,Mus musculus (Mouse), comp124582_c0_seq1,2316,35.6649,0.96629581,0,111,,3.00E-07,Q55GK8,Membrane-associated sulfotransferase kil1 (EC 2.8.2.-),Membrane-associated sulfotransferase kil1 (EC 2.8.2.-),GO:0042742; GO:0016021; GO:0006477; GO:0008146,defense response to bacterium; integral to membrane; protein sulfation; sulfotransferase activity,PF00685;,,,,,,,,,KIL1_DICDI,Dictyostelium discoideum (Slime mold),defense response to bacterium [GO:0042742]; protein sulfation [GO:0006477] comp124582_c0_seq2,2327,35.6682,0.96173737,0,1015,female,2.00E-53,O14792,Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1),Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1),GO:0005796; GO:0008467; GO:0005975; GO:0006024; GO:0016021; GO:0044281; GO:0008146,Golgi lumen; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; carbohydrate metabolic process; glycosaminoglycan biosynthetic process; integral to membrane; small molecule metabolic process; sulfotransferase activity,PF00685;,,,,,,,,,HS3S1_HUMAN,Homo sapiens (Human),glycosaminoglycan biosynthetic process [GO:0006024] comp124588_c0_seq1,284,48.5915,0.24691664,4,0,,,,,,,,,8.00E-11,CHOYP_contig_049491,,,,,,,,, comp124596_c1_seq2,344,45.0581,0.28779022,3,0,,3.00E-42,Q5U2V4,Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1),Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C],GO:0005576; GO:0016787; GO:0016042,extracellular region; hydrolase activity; lipid catabolic process,PF04916;,3.00E-42,CHOYP_LOC589177.1.1,,,,,,,PLBL1_RAT,Rattus norvegicus (Rat),lipid catabolic process [GO:0016042] comp124596_c4_seq1,594,42.5926,0.55921211,0,12,,7.00E-47,Q5U2V4,Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1),Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C],GO:0005576; GO:0016787; GO:0016042,extracellular region; hydrolase activity; lipid catabolic process,PF04916;,,,,,,,,,PLBL1_RAT,Rattus norvegicus (Rat),lipid catabolic process [GO:0016042] comp124599_c0_seq2,1247,41.2189,0.57756424,45,13,,,,,,,,,5.00E-47,CHOYP_LOC100888507.1.1,,,,,,,,, comp124600_c1_seq1,825,38.1818,0.50571503,19,113,,4.00E-17,Q9UPX8,SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1),SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1),GO:0030160; GO:0016324; GO:0031526; GO:0030054; GO:0060170; GO:0005737; GO:0043197; GO:0030426; GO:0035556; GO:0035255; GO:0043025; GO:0001917; GO:0001750; GO:0014069; GO:0045211,GKAP/Homer scaffold activity; apical plasma membrane; brush border membrane; cell junction; cilium membrane; cytoplasm; dendritic spine; growth cone; intracellular signal transduction; ionotropic glutamate receptor binding; neuronal cell body; photoreceptor inner segment; photoreceptor outer segment; postsynaptic density; postsynaptic membrane,PF00595;PF00536;PF07653;,1.00E-21,CHOYP_SHANK2.1.1,,,,,,,SHAN2_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; learning [GO:0007612]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625] comp124603_c0_seq2,962,38.7734,0.67260418,0,0,,2.00E-30,Q8GYB1,"Nudix hydrolase 15, mitochondrial (AtNUDT15) (EC 3.6.1.-) (Coenzyme A diphosphatase NUDT15)","Nudix hydrolase 15, mitochondrial (AtNUDT15) (EC 3.6.1.-) (Coenzyme A diphosphatase NUDT15)",GO:0010945; GO:0015937; GO:0008893; GO:0016787; GO:0046872; GO:0005739; GO:0006104,"CoA pyrophosphatase activity; coenzyme A biosynthetic process; guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; hydrolase activity; metal ion binding; mitochondrion; succinyl-CoA metabolic process",PF00293;,,,,,,,,,NUD15_ARATH,Arabidopsis thaliana (Mouse-ear cress),coenzyme A biosynthetic process [GO:0015937]; nucleoside phosphate metabolic process [GO:0006753]; succinyl-CoA metabolic process [GO:0006104] comp124615_c0_seq1,654,37.3089,1.32758208,1,108,,7.00E-26,B5SNZ6,Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS),Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS),GO:0005856; GO:0015031; GO:0006355; GO:0030017; GO:0006351,"cytoskeleton; protein transport; regulation of transcription, DNA-dependent; sarcomere; transcription, DNA-dependent",PF14705;,,,,,,,,,ABRA_PIG,Sus scrofa (Pig),"positive regulation of Rho protein signal transduction [GO:0035025]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124624_c0_seq1,467,46.8951,0.35755682,23,9,,,,,,,,,3.00E-18,CHOYP_LOC100878123.1.1,,,,,,,,, comp124624_c1_seq1,1367,41.3314,0.3648002,54,67,,2.00E-130,Q7Q021,Glycosyltransferase 25 family member (EC 2.-.-.-),Glycosyltransferase 25 family member (EC 2.-.-.-),GO:0005788; GO:0009103; GO:0016757,"endoplasmic reticulum lumen; lipopolysaccharide biosynthetic process; transferase activity, transferring glycosyl groups",PF01755;,6.00E-27,CHOYP_LOC100878123.1.1,,,,,,,GLT25_ANOGA,Anopheles gambiae (African malaria mosquito), comp124637_c0_seq1,1065,38.216,0.26089108,2287,14,male>female,6.00E-29,A7RR34,UPF0740 protein v1g200856,Protein Flattop homolog (Cilia- and flagella-associated protein 126),,,,,,,,,,,,U740_NEMVE,Nematostella vectensis (Starlet sea anemone),cilium organization [GO:0044782] comp124641_c0_seq2,2048,37.4023,0.51700094,12,71,,8.00E-33,Q32L09,UPF0515 protein C19orf66 homolog,Repressor of yield of DENV protein homolog (RyDEN),,,PF15135;,,,,,,,,,CS066_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; negative regulation of viral genome replication [GO:0045071]; response to interferon-gamma [GO:0034341]; response to type III interferon [GO:0034342]; response to type I interferon [GO:0034340] comp124644_c1_seq1,891,45.1178,0.87572168,30,16,,7.00E-49,Q5ZJ69,AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B),AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B),GO:0060612; GO:0005634; GO:0051091; GO:0044212; GO:0006351,"adipose tissue development; nucleus; positive regulation of sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",PF01388;,5.00E-13,CHOYP_H6.1.1,,,,,,,ARI5B_CHICK,Gallus gallus (Chicken),"adipose tissue development [GO:0060612]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp124648_c0_seq1,542,44.6494,0.94369456,0,8,,3.00E-27,P25773,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Progesterone-dependent protein) (PDP) (Fragment),Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Progesterone-dependent protein) (PDP) (Fragment),GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF00112;,1.00E-17,CHOYP_CATL.1.1,3.00E-17,ruditapes_c3797,,,,,CATL1_FELCA,Felis catus (Cat) (Felis silvestris catus),proteolysis involved in cellular protein catabolic process [GO:0051603] comp124648_c0_seq2,794,44.9622,1.01138765,4,40,,2.00E-82,Q26636,Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],GO:0030154; GO:0008234; GO:0005764; GO:0007275; GO:0006508,cell differentiation; cysteine-type peptidase activity; lysosome; multicellular organismal development; proteolysis,PF08246;PF00112;,1.00E-19,CHOYP_CTSL2.1.2,6.00E-16,ruditapes_c4044,,,,,CATL_SARPE,Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp124654_c0_seq1,647,31.221,0.31789715,5,0,,,,,,,,,6.00E-11,CHOYP_DVIR_GJ13079.1.1,,,,,,,,, comp124654_c0_seq4,209,36.3636,0.44745343,1,0,,,,,,,,,5.00E-12,CHOYP_contig_050087,,,,,,,,, comp124654_c0_seq5,587,30.8348,0.29704557,11,51,,,,,,,,,5.00E-11,CHOYP_contig_054043,,,,,,,,, comp124656_c1_seq1,739,48.5792,0.81069386,12,60,,1.00E-90,Q6ZN04,RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) (RING finger protein 195),RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) (RING finger protein 195),GO:0003723; GO:0005509; GO:0005737; GO:0000932; GO:0005634; GO:0046777; GO:0008270,RNA binding; calcium ion binding; cytoplasm; cytoplasmic mRNA processing body; nucleus; protein autophosphorylation; zinc ion binding,PF00013;,2.00E-99,CHOYP_MEX3B.1.1,,,,,,,MEX3B_HUMAN,Homo sapiens (Human),protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp124660_c0_seq1,1097,40.7475,0.35929349,63,58,,3.00E-08,Q6DH86,Coiled-coil domain-containing protein 149-B,Coiled-coil domain-containing protein 149-B,,,PF09789;,2.00E-14,CHOYP_LOC100344710.1.1,,,,,,,C149B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp124669_c0_seq1,808,49.8762,0.86123622,27,819,,2.00E-32,P37801,Calponin homolog OV9M,Calponin homolog OV9M,,,PF00402;,,,1.00E-12,ruditapes_lrc7057,,,,,CLPH_ONCVO,Onchocerca volvulus, comp124669_c0_seq2,1492,39.6113,1.19332136,152,2215,,,,,,,,,,,3.00E-29,ruditapes2_c3343,,,,,,, comp124678_c0_seq1,375,47.4667,0.91590395,5,10,,5.00E-22,A8G7S7,Glyoxylate/hydroxypyruvate reductase B (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate/hydroxypyruvate reductase B (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0005737; GO:0030267; GO:0016618; GO:0005886,NAD binding; cytoplasm; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; plasma membrane,PF00389;PF02826;,,,,,,,,,GHRB_SERP5,Serratia proteamaculans (strain 568), comp124678_c0_seq2,229,44.9782,0.86794108,0,4,,3.00E-08,Q9Z2F5,C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) (C-terminal-binding protein 3) (CtBP3),C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) (C-terminal-binding protein 3) (CtBP3),GO:0007030; GO:0051287; GO:0001106; GO:0005829; GO:0061025; GO:0090241; GO:0045892; GO:0016616; GO:0031065; GO:0051726; GO:0034401; GO:0003700; GO:0003714; GO:0005667; GO:0017053; GO:0016746; GO:0050872,"Golgi organization; NAD binding; RNA polymerase II transcription corepressor activity; cytosol; membrane fusion; negative regulation of histone H4 acetylation; negative regulation of transcription, DNA-dependent; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; positive regulation of histone deacetylation; regulation of cell cycle; regulation of transcription by chromatin organization; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; transcription factor complex; transcriptional repressor complex; transferase activity, transferring acyl groups; white fat cell differentiation",PF00389;PF02826;,,,,,,,,,CTBP1_RAT,Rattus norvegicus (Rat),"membrane fusion [GO:0061025]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp124678_c0_seq3,272,47.7941,0.7114524,0,0,,5.00E-14,B5YVQ3,Glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) (EC 1.1.1.81) (2-ketoacid reductase),Glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) (EC 1.1.1.81) (2-ketoacid reductase),GO:0048037; GO:0005737; GO:0030267; GO:0016618; GO:0005886,cofactor binding; cytoplasm; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; plasma membrane,PF02826;,,,,,,,,,GHRA_ECO5E,Escherichia coli O157:H7 (strain EC4115 / EHEC), comp124684_c0_seq5,852,41.5493,0.72116641,2,16,,,,,,,,,,,4.00E-25,ruditapes_c10477,,,,,,, comp124686_c0_seq2,588,51.0204,0.52505055,7,18,,2.00E-28,Q9Y2M2,Protein SSUH2 homolog (Protein ssu-2 homolog),Protein SSUH2 homolog (Protein ssu-2 homolog),GO:0005737,cytoplasm,,7.00E-28,CHOYP_BRAFLDRAFT_276314.3.3,,,,,,,CC032_HUMAN,Homo sapiens (Human), comp124686_c1_seq2,363,48.4848,0.37623025,2,30,,9.00E-18,Q8C3L1,Protein SSUH2 homolog (Protein ssu-2 homolog),Protein SSUH2 homolog (Protein ssu-2 homolog),GO:0005737,cytoplasm,,1.00E-16,CHOYP_LOC763611.2.2,,,,,,,CC032_MOUSE,Mus musculus (Mouse), comp124687_c0_seq2,695,42.0144,0.23387145,8,22,,,,,,,,,,,4.00E-11,ruditapes2_c1164,,,,,,, comp124693_c0_seq1,733,40.9277,1.11515467,19,99,,5.00E-15,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp124701_c1_seq1,773,31.9534,0.86679987,7,25,,6.00E-11,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp124715_c0_seq3,978,39.1616,1.07170336,20,19,,8.00E-25,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp124719_c0_seq1,1424,40.4494,0.5048564,53,126,,7.00E-86,Q9JJ59,ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL),ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL),GO:0005524; GO:0042288; GO:0042825; GO:0046978; GO:0046979; GO:0005765; GO:0005764; GO:0015421; GO:0042605; GO:0005886; GO:0001916; GO:0015031; GO:0046980,ATP binding; MHC class I protein binding; TAP complex; TAP1 binding; TAP2 binding; lysosomal membrane; lysosome; oligopeptide-transporting ATPase activity; peptide antigen binding; plasma membrane; positive regulation of T cell mediated cytotoxicity; protein transport; tapasin binding,PF00664;PF00005;,,,,,,,,,ABCB9_MOUSE,Mus musculus (Mouse),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]" comp124723_c0_seq1,2041,51.0044,0.53711373,197,37,,3.00E-23,Q7Z7A1,Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110),Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110),GO:0000086; GO:0051301; GO:0005813; GO:0005829,G2/M transition of mitotic cell cycle; cell division; centrosome; cytosol,,2.00E-16,CHOYP_LOC100175166.1.1,,,,,,,CNTRL_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086] comp124728_c0_seq1,655,33.1298,0.27962555,316,1103,,,,,,,,,,,7.00E-14,ruditapes2_c2116,,,,,,, comp124731_c0_seq1,478,42.887,0.55536475,15,21,,,,,,,,,4.00E-18,CHOYP_LOC100367685.1.1,,,,,,,,, comp124731_c1_seq1,916,44.5415,0.5562167,37,66,,7.00E-36,Q9SKB3,Poly(ADP-ribose) glycohydrolase 1 (EC 3.2.1.143),Poly(ADP-ribose) glycohydrolase 1 (EC 3.2.1.143),GO:0005975; GO:0050832; GO:0004649; GO:0006970; GO:0006979; GO:0009414; GO:0048511; GO:0090332,carbohydrate metabolic process; defense response to fungus; poly(ADP-ribose) glycohydrolase activity; response to osmotic stress; response to oxidative stress; response to water deprivation; rhythmic process; stomatal closure,PF05028;,,,,,,,,,PARG1_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; defense response to fungus [GO:0050832]; regulation of DNA repair [GO:0006282]; response to osmotic stress [GO:0006970]; response to oxidative stress [GO:0006979]; response to water deprivation [GO:0009414]; rhythmic process [GO:0048511]; stomatal closure [GO:0090332] comp124733_c0_seq1,1258,39.4277,0.96517644,657,4959,,2.00E-14,Q6PBD7,DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2),DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2),GO:0043425; GO:0090398; GO:0005737; GO:0048557; GO:0061031; GO:2000178; GO:0045665; GO:0000122; GO:0048663; GO:0005634; GO:0045777; GO:0071158; GO:0048661; GO:0045893; GO:0043234,"bHLH transcription factor binding; cellular senescence; cytoplasm; embryonic digestive tract morphogenesis; endodermal digestive tract morphogenesis; negative regulation of neural precursor cell proliferation; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; neuron fate commitment; nucleus; positive regulation of blood pressure; positive regulation of cell cycle arrest; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; protein complex",PF00010;,,,5.00E-38,ruditapes_c1161,,,,,ID2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cellular senescence [GO:0090398]; embryonic digestive tract morphogenesis [GO:0048557]; endodermal digestive tract morphogenesis [GO:0061031]; negative regulation of gene expression [GO:0010629]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron fate commitment [GO:0048663]; positive regulation of blood pressure [GO:0045777]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of gene expression [GO:0010628]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp124739_c0_seq1,216,42.5926,0.10663619,36,25,,3.00E-08,Q70AD6,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0005737; GO:0000166; GO:0005634; GO:0009881; GO:0018298; GO:0042752; GO:0006355; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; cytoplasm; nucleotide binding; nucleus; photoreceptor activity; protein-chromophore linkage; regulation of circadian rhythm; regulation of transcription, DNA-dependent; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY1_SPAJD,Spalax judaei (Judean Mountains blind mole rat) (Nannospalax judaei),"circadian regulation of gene expression [GO:0032922]; DNA damage induced protein phosphorylation [GO:0006975]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to glucagon [GO:0033762]; transcription, DNA-templated [GO:0006351]" comp124744_c0_seq1,1572,39.8855,0.60994575,0,0,,5.00E-11,Q9XZ71,Troponin T (TnT),Troponin T (TnT),GO:0006937; GO:0005861,regulation of muscle contraction; troponin complex,PF00992;,,,,,,,,,TNNT_PERAM,Periplaneta americana (American cockroach) (Blatta americana),regulation of muscle contraction [GO:0006937] comp124744_c0_seq11,1089,42.3324,0.63591427,0,0,,2.00E-11,Q9XZ71,Troponin T (TnT),Troponin T (TnT),GO:0006937; GO:0005861,regulation of muscle contraction; troponin complex,PF00992;,,,,,,,,,TNNT_PERAM,Periplaneta americana (American cockroach) (Blatta americana),regulation of muscle contraction [GO:0006937] comp124744_c0_seq3,1509,38.9662,0.63800791,0,0,,,,,,,,,,,3.00E-29,ruditapes2_c2219,,,,,,, comp124744_c0_seq9,1618,39.4314,0.60738173,0,0,,5.00E-11,Q9XZ71,Troponin T (TnT),Troponin T (TnT),GO:0006937; GO:0005861,regulation of muscle contraction; troponin complex,PF00992;,,,,,,,,,TNNT_PERAM,Periplaneta americana (American cockroach) (Blatta americana),regulation of muscle contraction [GO:0006937] comp124745_c0_seq1,698,33.8109,0.40913166,12,137,,1.00E-30,Q6IUR5,Neudesin (Neuron-derived neurotrophic factor) (SCIRP10-related protein) (Spinal cord injury-related protein 10),Neudesin (Neuron-derived neurotrophic factor) (SCIRP10-related protein) (Spinal cord injury-related protein 10),GO:0005615; GO:0020037; GO:0046872; GO:0043410,extracellular space; heme binding; metal ion binding; positive regulation of MAPK cascade,PF00173;,,,3.00E-25,ruditapes_c23654,,,,,NENF_RAT,Rattus norvegicus (Rat),negative regulation of appetite [GO:0032099]; positive regulation of MAPK cascade [GO:0043410] comp124761_c0_seq1,769,40.052,0.4279248,4,0,,1.00E-25,Q2KIY1,Peroxisomal membrane protein 2,Peroxisomal membrane protein 2,GO:0016021; GO:0005778; GO:0043234,integral to membrane; peroxisomal membrane; protein complex,PF04117;,,,,,,,,,PXMP2_BOVIN,Bos taurus (Bovine), comp124761_c0_seq2,815,39.3865,0.41862731,3,15,,1.00E-19,P42925,Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane protein),Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane protein),GO:0016021; GO:0005739; GO:0005778,integral to membrane; mitochondrion; peroxisomal membrane,PF04117;,2.00E-18,CHOYP_LOC100368884.1.1,,,,,,,PXMP2_MOUSE,Mus musculus (Mouse), comp124770_c0_seq1,1083,40.3509,0.50352646,154,154,,3.00E-59,Q4V7W8,Methyltransferase-like protein 20 (EC 2.1.1.-),Electron transfer flavoprotein beta subunit lysine methyltransferase (EC 2.1.1.-) (ETFB lysine methyltransferase) (ETFB-KMT) (Protein N-lysine methyltransferase METTL20),GO:0005737; GO:0008276,cytoplasm; protein methyltransferase activity,,3.00E-16,CHOYP_LOC100166013.1.1,,,,,,,MET20_XENLA,Xenopus laevis (African clawed frog),negative regulation of electron carrier activity [GO:1904733]; negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:1904736]; peptidyl-lysine trimethylation [GO:0018023] comp124774_c0_seq1,282,42.9078,0.96259714,0,84,,3.00E-18,Q04833,Low-density lipoprotein receptor-related protein (LRP),Low-density lipoprotein receptor-related protein (LRP),GO:0016324; GO:0005509; GO:0005905; GO:0042395; GO:0030139; GO:0006897; GO:0016021; GO:0002119; GO:0040017; GO:0040018; GO:0030334; GO:0015248,"apical plasma membrane; calcium ion binding; coated pit; ecdysis, collagen and cuticulin-based cuticle; endocytic vesicle; endocytosis; integral to membrane; nematode larval development; positive regulation of locomotion; positive regulation of multicellular organism growth; regulation of cell migration; sterol transporter activity",PF00057;PF00058;,,,,,,,,,LRP_CAEEL,Caenorhabditis elegans,"ecdysis, collagen and cuticulin-based cuticle [GO:0042395]; endocytosis [GO:0006897]; nematode larval development [GO:0002119]; positive regulation of locomotion [GO:0040017]; positive regulation of multicellular organism growth [GO:0040018]; regulation of cell migration [GO:0030334]; sterol transport [GO:0015918]" comp124775_c3_seq1,956,36.4017,0.76166557,62,222,,6.00E-11,Q6DGX3,Ankyrin repeat domain-containing protein 54,Ankyrin repeat domain-containing protein 54,GO:0005737; GO:0030496; GO:0005634,cytoplasm; midbody; nucleus,PF00023;PF12796;,9.00E-17,CHOYP_LOC655990.1.1,3.00E-64,ruditapes_c15227,,,,,ANR54_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp124781_c0_seq1,406,48.0296,0.30321597,12,44,,3.00E-21,Q5ZMQ9,Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1),Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1),GO:0005829; GO:0005778; GO:0005052; GO:0016560,"cytosol; peroxisomal membrane; peroxisome matrix targeting signal-1 binding; protein import into peroxisome matrix, docking",,,,,,,,,,PEX5_CHICK,Gallus gallus (Chicken),"protein import into peroxisome matrix, docking [GO:0016560]" comp124789_c1_seq1,1535,45.5375,0.57435376,3,0,,1.00E-13,Q99550,M-phase phosphoprotein 9,M-phase phosphoprotein 9,GO:0005794; GO:0000139; GO:0005814; GO:0000087; GO:0005634; GO:0005886,Golgi apparatus; Golgi membrane; centriole; mitotic M phase; nucleus; plasma membrane,,,,,,,,,,MPP9_HUMAN,Homo sapiens (Human), comp124796_c0_seq1,1383,40.7086,0.68666964,81,72,,2.00E-52,Q80T74,Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),,,PF07707;PF00651;PF01344;,2.00E-65,CHOYP_KLH24.5.6,,,,,,,KLH29_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp124799_c0_seq1,337,41.2463,0.2100267,9,8,,1.00E-21,Q92794,"Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)","Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)",GO:0003677; GO:0006323; GO:0070776; GO:0016605; GO:0035909; GO:0090398; GO:0003682; GO:0035162; GO:0060325; GO:0003007; GO:0043966; GO:0004402; GO:0030099; GO:0043433; GO:0045892; GO:0005730; GO:0000786; GO:0006334; GO:0045893; GO:0035019; GO:0003713; GO:0008134; GO:0006351; GO:0008270,"DNA binding; DNA packaging; MOZ/MORF histone acetyltransferase complex; PML body; aorta morphogenesis; cellular senescence; chromatin binding; embryonic hemopoiesis; face morphogenesis; heart morphogenesis; histone H3 acetylation; histone acetyltransferase activity; myeloid cell differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; nucleolus; nucleosome; nucleosome assembly; positive regulation of transcription, DNA-dependent; somatic stem cell maintenance; transcription coactivator activity; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF01853;PF00628;,,,,,,,,,KAT6A_HUMAN,Homo sapiens (Human),"cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp124799_c1_seq1,1276,40.5172,0.34884378,50,140,,4.00E-17,Q5VXD3,Sterile alpha motif domain-containing protein 13 (SAM domain-containing protein 13),Sterile alpha motif domain-containing protein 13 (SAM domain-containing protein 13),,,PF00536;,,,,,,,,,SAM13_HUMAN,Homo sapiens (Human), comp124804_c0_seq1,941,45.5898,0.38935825,58,22,,3.00E-81,A2AF47,Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2),Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2),GO:0005089; GO:0005543; GO:0007264,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;PF00169;,4.00E-34,CHOYP_DOCK9.1.2,,,,,,,DOC11_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp124805_c0_seq1,1016,42.5197,0.39304386,56,79,,5.00E-90,Q4R5T4,RING finger protein 32,RING finger protein 32,GO:0005737; GO:0008270,cytoplasm; zinc ion binding,PF00612;PF13639;PF13445;,7.00E-63,CHOYP_LOC581813.1.1,,,,,,,RNF32_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp124813_c0_seq1,1909,45.2593,0.49177176,7,4,,2.00E-88,A4IFD0,Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5),Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5),GO:0005524; GO:0046034; GO:0004017; GO:0005813; GO:0005737; GO:0004550; GO:0019206; GO:0009142,ATP binding; ATP metabolic process; adenylate kinase activity; centrosome; cytoplasm; nucleoside diphosphate kinase activity; nucleoside kinase activity; nucleoside triphosphate biosynthetic process,,5.00E-23,CHOYP_VOLCADRAFT_121426.1.1,,,,,,,KAD5_BOVIN,Bos taurus (Bovine),ATP metabolic process [GO:0046034]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp124813_c0_seq3,1654,46.1911,0.48784936,4,0,,1.00E-16,Q3IMW0,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm,,,,,,,,,,KAD_NATPD,Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis),AMP salvage [GO:0044209] comp124813_c0_seq4,1924,45.1143,0.49107156,15,0,,3.00E-17,O96907,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0005524; GO:0004017; GO:0005737,ATP binding; adenylate kinase activity; cytoplasm,,,,,,,,,,KAD_ENTHI,Entamoeba histolytica, comp124824_c0_seq1,548,38.5036,0.70578747,19,116,,3.00E-58,Q6DJF8,Methyltransferase-like protein 23 (EC 2.1.1.-),Methyltransferase-like protein 23 (EC 2.1.1.-),GO:0005737; GO:0016021; GO:0008168,cytoplasm; integral to membrane; methyltransferase activity,PF10294;,6.00E-16,CHOYP_MET23.1.1,,,,,,,MET23_XENLA,Xenopus laevis (African clawed frog), comp124827_c0_seq1,338,31.3609,1.94201485,11,6,,,,,,,,,,,2.00E-16,ruditapes_c20632,,,,,,, comp124834_c0_seq1,344,44.7674,0.70588832,6,0,,1.00E-06,O42844,Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17),Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17),GO:0005524; GO:0051519; GO:0005509; GO:0004683; GO:0030428; GO:0034599; GO:0005737; GO:0033314; GO:0031098,ATP binding; activation of bipolar cell growth; calcium ion binding; calmodulin-dependent protein kinase activity; cell septum; cellular response to oxidative stress; cytoplasm; mitotic DNA replication checkpoint; stress-activated protein kinase signaling cascade,PF00069;,,,,,,,,,KCC2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular response to oxidative stress [GO:0034599]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; protein autophosphorylation [GO:0046777]; stress-activated protein kinase signaling cascade [GO:0031098] comp124834_c0_seq2,223,41.704,0.62512885,0,6,,1.00E-13,P43290,Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34cdc2) (Fragment),Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34cdc2) (Fragment),GO:0005524; GO:0008353; GO:0051301; GO:0004693; GO:0007067,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cell division; cyclin-dependent protein serine/threonine kinase activity; mitosis,PF00069;,,,,,,,,,CDC2_PETHY,Petunia hybrida (Petunia),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp124834_c1_seq3,861,43.6702,0.41984986,0,0,,3.00E-24,Q01917,Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23),Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23),GO:0005524; GO:0008353; GO:0051301; GO:0004693; GO:0007067,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cell division; cyclin-dependent protein serine/threonine kinase activity; mitosis,PF00069;,,,,,,,,,CDC2H_CRIFA,Crithidia fasciculata,cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp124834_c1_seq4,946,42.9175,0.44281791,5,8,,3.00E-125,Q00537,Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2),Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2),GO:0005524; GO:0004693; GO:0004672,ATP binding; cyclin-dependent protein serine/threonine kinase activity; protein kinase activity,PF00069;,8.00E-106,CHOYP_LOC101068677.1.1,,,,,,,CDK17_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468] comp124838_c0_seq1,463,39.3089,0.39804107,27,73,,7.00E-34,Q2HJ54,Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) (Phosphatidylinositol-transfer protein 35 kDa isoform) (PI-TP 35 kda isoform),Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) (Phosphatidylinositol-transfer protein 35 kDa isoform) (PI-TP 35 kda isoform),GO:0005737; GO:0008289; GO:0006810,cytoplasm; lipid binding; transport,PF02121;,1.00E-29,CHOYP_PIPNA.1.1,,,,,,,PIPNA_BOVIN,Bos taurus (Bovine),transport [GO:0006810] comp124841_c0_seq1,1134,36.8607,0.8091544,39,378,,4.00E-08,Q69DL0,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit A,GO:0005581; GO:0006958; GO:0045087,"collagen; complement activation, classical pathway; innate immune response",PF00386;PF01391;,,,,,,,,,C1QA_PIG,Sus scrofa (Pig),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]" comp124849_c0_seq1,740,42.7027,0.47509604,38,31,,2.00E-29,Q8NG08,DNA helicase B (hDHB) (EC 3.6.4.12),DNA helicase B (hDHB) (EC 3.6.4.12),GO:0005524; GO:0043141; GO:0006269; GO:0017116,"ATP binding; ATP-dependent 5'-3' DNA helicase activity; DNA replication, synthesis of RNA primer; single-stranded DNA-dependent ATP-dependent DNA helicase activity",PF13538;,,,,,,,,,HELB_HUMAN,Homo sapiens (Human),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA double-strand break processing [GO:1903775]" comp124853_c0_seq1,486,44.856,0.56002006,15,13,,2.00E-16,Q61851,Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Heparin-binding growth factor receptor) (CD antigen CD333),Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Heparin-binding growth factor receptor) (CD antigen CD333),GO:0005524; GO:0000165; GO:0061144; GO:0060385; GO:0070977; GO:0060349; GO:0051216; GO:0022010; GO:0090102; GO:0016023; GO:0048546; GO:0005783; GO:0072148; GO:0017134; GO:1902178; GO:0005007; GO:0060113; GO:0005887; GO:0009898; GO:0070307; GO:0002089; GO:0005764; GO:0002009; GO:0048712; GO:0048640; GO:0050680; GO:0045839; GO:0045879; GO:0000122; GO:0048471; GO:0070374; GO:0090080; GO:0090263; GO:0045597; GO:0001938; GO:0043525; GO:0043552; GO:0010518; GO:0031398; GO:0042511; GO:0042517; GO:0036342; GO:0046777; GO:0048678; GO:0035019; GO:0021762,ATP binding; MAPK cascade; alveolar secondary septum development; axonogenesis involved in innervation; bone maturation; bone morphogenesis; cartilage development; central nervous system myelination; cochlea development; cytoplasmic membrane-bounded vesicle; digestive tract morphogenesis; endoplasmic reticulum; epithelial cell fate commitment; fibroblast growth factor binding; fibroblast growth factor receptor signaling pathway involved in apoptotic process; fibroblast growth factor-activated receptor activity; inner ear receptor cell differentiation; integral to plasma membrane; internal side of plasma membrane; lens fiber cell development; lens morphogenesis in camera-type eye; lysosome; morphogenesis of an epithelium; negative regulation of astrocyte differentiation; negative regulation of developmental growth; negative regulation of epithelial cell proliferation; negative regulation of mitosis; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; perinuclear region of cytoplasm; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell differentiation; positive regulation of endothelial cell proliferation; positive regulation of neuron apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of phospholipase activity; positive regulation of protein ubiquitination; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; post-anal tail morphogenesis; protein autophosphorylation; response to axon injury; somatic stem cell maintenance; substantia nigra development,PF07679;PF07714;,,,,,,,,,FGFR3_MOUSE,Mus musculus (Mouse),alveolar secondary septum development [GO:0061144]; axonogenesis involved in innervation [GO:0060385]; bone development [GO:0060348]; bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; bone trabecula morphogenesis [GO:0061430]; cartilage development [GO:0051216]; cell differentiation [GO:0030154]; central nervous system myelination [GO:0022010]; cochlea development [GO:0090102]; digestive tract morphogenesis [GO:0048546]; epithelial cell fate commitment [GO:0072148]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; forebrain development [GO:0030900]; inner ear development [GO:0048839]; inner ear receptor cell differentiation [GO:0060113]; lens fiber cell development [GO:0070307]; lens morphogenesis in camera-type eye [GO:0002089]; MAPK cascade [GO:0000165]; morphogenesis of an epithelium [GO:0002009]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell proliferation [GO:0008285]; negative regulation of developmental growth [GO:0048640]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of gene expression [GO:0010629]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oligodendrocyte development [GO:0014003]; p38MAPK cascade [GO:0038066]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of tyrosine phosphorylation of Stat1 protein [GO:0042511]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; post-anal tail morphogenesis [GO:0036342]; protein autophosphorylation [GO:0046777]; regulation of bone remodeling [GO:0046850]; regulation of collagen metabolic process [GO:0010712]; regulation of ossification [GO:0030278]; regulation of osteoclast differentiation [GO:0045670]; response to axon injury [GO:0048678]; somatic stem cell population maintenance [GO:0035019]; substantia nigra development [GO:0021762] comp124858_c0_seq1,876,46.5753,0.8173156,172,3702,,1.00E-35,Q2KJ63,Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],GO:0007596; GO:0005576; GO:0042730; GO:0006954; GO:0006508; GO:0004252,blood coagulation; extracellular region; fibrinolysis; inflammatory response; proteolysis; serine-type endopeptidase activity,PF00024;PF14295;PF00089;,,,,,,,,,KLKB1_BOVIN,Bos taurus (Bovine),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919] comp124862_c0_seq1,1101,40.8719,0.28354303,11,15,,1.00E-51,O46043,Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143),Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143),GO:0030576; GO:0005975; GO:0006342; GO:0036099; GO:0051457; GO:0005654; GO:0006909; GO:0004649; GO:0043484; GO:0035065; GO:0009408,Cajal body organization; carbohydrate metabolic process; chromatin silencing; female germ-line stem cell maintenance; maintenance of protein location in nucleus; nucleoplasm; phagocytosis; poly(ADP-ribose) glycohydrolase activity; regulation of RNA splicing; regulation of histone acetylation; response to heat,PF05028;,,,,,,,,,PARG_DROME,Drosophila melanogaster (Fruit fly),Cajal body organization [GO:0030576]; carbohydrate metabolic process [GO:0005975]; chromatin silencing [GO:0006342]; female germ-line stem cell population maintenance [GO:0036099]; maintenance of protein location in nucleus [GO:0051457]; phagocytosis [GO:0006909]; regulation of histone acetylation [GO:0035065]; regulation of RNA splicing [GO:0043484]; response to heat [GO:0009408] comp124862_c0_seq2,782,41.4322,0.18000029,0,0,,2.00E-13,O46043,Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143),Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143),GO:0030576; GO:0005975; GO:0006342; GO:0036099; GO:0051457; GO:0005654; GO:0006909; GO:0004649; GO:0043484; GO:0035065; GO:0009408,Cajal body organization; carbohydrate metabolic process; chromatin silencing; female germ-line stem cell maintenance; maintenance of protein location in nucleus; nucleoplasm; phagocytosis; poly(ADP-ribose) glycohydrolase activity; regulation of RNA splicing; regulation of histone acetylation; response to heat,PF05028;,,,,,,,,,PARG_DROME,Drosophila melanogaster (Fruit fly),Cajal body organization [GO:0030576]; carbohydrate metabolic process [GO:0005975]; chromatin silencing [GO:0006342]; female germ-line stem cell population maintenance [GO:0036099]; maintenance of protein location in nucleus [GO:0051457]; phagocytosis [GO:0006909]; regulation of histone acetylation [GO:0035065]; regulation of RNA splicing [GO:0043484]; response to heat [GO:0009408] comp124864_c0_seq3,1174,41.5673,0.81004565,17,151,,8.00E-32,Q9WTP3,SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor),SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor),GO:0060576; GO:0060480; GO:0010454; GO:0000122; GO:0005634; GO:0043065; GO:0010455; GO:0045944; GO:0043565; GO:0003700; GO:0006351,"intestinal epithelial cell development; lung goblet cell differentiation; negative regulation of cell fate commitment; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of apoptotic process; positive regulation of cell fate commitment; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,3.00E-24,CHOYP_ETS4.1.2,3.00E-28,ruditapes_c10390,,,,,SPDEF_MOUSE,Mus musculus (Mouse),"intestinal epithelial cell development [GO:0060576]; lung goblet cell differentiation [GO:0060480]; negative regulation of cell fate commitment [GO:0010454]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell fate commitment [GO:0010455]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp124866_c0_seq1,483,43.2712,0.49461379,33,23,,4.00E-30,Q9QYF1,Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (Cell line MC/9.IL4-derived protein 1) (M42C60) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short-chain aldehyde dehydrogenase) (SCALD),Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (Cell line MC/9.IL4-derived protein 1) (M42C60) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short-chain aldehyde dehydrogenase) (SCALD),GO:0052650; GO:0016062; GO:0005789; GO:0016021; GO:0005622; GO:0001917; GO:0042574; GO:0004745,NADP-retinol dehydrogenase activity; adaptation of rhodopsin mediated signaling; endoplasmic reticulum membrane; integral to membrane; intracellular; photoreceptor inner segment; retinal metabolic process; retinol dehydrogenase activity,PF00106;,6.00E-22,CHOYP_TRIADDRAFT_37121.1.1,,,,,,,RDH11_MOUSE,Mus musculus (Mouse),adaptation of rhodopsin mediated signaling [GO:0016062]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] comp124866_c1_seq2,668,42.6647,0.23764389,9,8,,5.00E-34,Q9ERI6,Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2),Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2),GO:0005783; GO:0005739; GO:0016491,endoplasmic reticulum; mitochondrion; oxidoreductase activity,PF00106;,,,,,,,,,RDH14_MOUSE,Mus musculus (Mouse),osteoblast differentiation [GO:0001649]; retinol metabolic process [GO:0042572] comp124871_c1_seq1,344,33.7209,0.71875607,5,22,,,,,,,,,1.00E-16,CHOYP_SMC3.1.1,,,,,,,,, comp124871_c1_seq2,352,33.8068,0.40022999,12,52,,,,,,,,,1.00E-16,CHOYP_contig_020819,,,,,,,,, comp124874_c0_seq1,1307,39.8623,0.36736163,3675,21,male>female,7.00E-09,Q03407,Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1),Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1),GO:0005524; GO:0000196; GO:0005938; GO:0033962; GO:0005829; GO:0032126; GO:0006897; GO:0004672; GO:0004674; GO:0060211,ATP binding; MAPK cascade involved in cell wall biogenesis; cell cortex; cytoplasmic mRNA processing body assembly; cytosol; eisosome; endocytosis; protein kinase activity; protein serine/threonine kinase activity; regulation of nuclear-transcribed mRNA poly(A) tail shortening,PF00069;,,,,,,,,,PKH1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cytoplasmic mRNA processing body assembly [GO:0033962]; endocytosis [GO:0006897]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; MAPK cascade involved in cell wall organization or biogenesis [GO:0000196]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060211] comp124877_c1_seq1,1344,46.3542,0.66543018,51,5,,,,,,,,,5.00E-15,CHOYP_BRAFLDRAFT_85465.1.1,,,,,,,,, comp124877_c2_seq1,461,43.6009,0.32115345,21,10,,4.00E-06,Q9P2H0,Uncharacterized protein KIAA1377,Centrosomal protein of 126 kDa,GO:0030496,midbody,PF15352;,,,,,,,,,K1377_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; mitotic spindle organization [GO:0007052]; nonmotile primary cilium assembly [GO:0035058] comp124881_c1_seq1,310,44.5161,0.60052116,13,206,,3.00E-17,Q8TGM7,Putative uncharacterized protein ART2 (Antisense to ribosomal RNA transcript protein 2),Putative uncharacterized protein ART2 (Antisense to ribosomal RNA transcript protein 2),,,,4.00E-78,CHOYP_MTR_5G050970.1.1,,,,,,,ART2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp124885_c1_seq3,1240,42.4194,0.30696388,0,0,,5.00E-07,O43184,Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha),Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha),GO:0007155; GO:0007173; GO:0005576; GO:0016021; GO:0004222; GO:0008237; GO:0005739; GO:0007520; GO:0005634; GO:0005886; GO:0006508; GO:0008270,cell adhesion; epidermal growth factor receptor signaling pathway; extracellular region; integral to membrane; metalloendopeptidase activity; metallopeptidase activity; mitochondrion; myoblast fusion; nucleus; plasma membrane; proteolysis; zinc ion binding,PF08516;PF00200;PF01562;PF01421;,,,,,,,,,ADA12_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; myoblast fusion [GO:0007520] comp124893_c1_seq1,1793,41.5505,0.57324637,87,129,,0,O77237,Protein pellino,Protein pellino,GO:0008063; GO:0006955; GO:0019207,Toll signaling pathway; immune response; kinase regulator activity,PF04710;,6.00E-155,CHOYP_PELI.1.1,,,,,,,PELI_DROME,Drosophila melanogaster (Fruit fly),defense response [GO:0006952]; immune response [GO:0006955]; negative regulation of antimicrobial humoral response [GO:0008348]; negative regulation of Toll signaling pathway [GO:0045751]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; regulation of phosphorylation [GO:0042325]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063] comp124918_c0_seq1,1372,45.2624,0.76907638,56,35,,2.00E-82,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,2.00E-33,CHOYP_BRAFLDRAFT_119774.3.4,2.00E-24,ruditapes_c15932,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp124918_c0_seq2,346,45.3757,0.73350206,6,0,,,,,,,,,2.00E-31,CHOYP_BRAFLDRAFT_108900.1.1,,,,,,,,, comp124922_c0_seq1,784,38.2653,0.87226241,0,0,,2.00E-25,O16025,Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],GO:0047677; GO:0019369; GO:0004096; GO:0005737; GO:0020037; GO:0047987; GO:0005506; GO:0016020; GO:0031408,arachidonate 8(R)-lipoxygenase activity; arachidonic acid metabolic process; catalase activity; cytoplasm; heme binding; hydroperoxide dehydratase activity; iron ion binding; membrane; oxylipin biosynthetic process,PF00305;PF01477;,,,,,,,,,AOSL_PLEHO,Plexaura homomalla (Black sea rod),arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408] comp124924_c0_seq3,2033,38.2686,0.39229858,100,43,,9.00E-70,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,4.00E-44,CHOYP_SACS.3.17,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp124924_c3_seq1,1427,40.4345,0.45016754,89,17,,5.00E-30,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp124925_c0_seq1,863,39.5133,0.44862979,3315,606,,1.00E-16,Q99PE9,ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L) (ADP-ribosylation factor-like protein 5),ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L) (ADP-ribosylation factor-like protein 5),GO:0005525; GO:0005737; GO:0005730; GO:0005634; GO:0005886; GO:0007264,GTP binding; cytoplasm; nucleolus; nucleus; plasma membrane; small GTPase mediated signal transduction,PF00025;,,,,,,,,,ARL4D_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp124927_c0_seq1,531,43.8795,0.55048237,31,20,,2.00E-33,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,2.00E-34,CHOYP_VP13D.1.3,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp124929_c0_seq2,291,38.1443,0.37947167,4,17,,5.00E-16,Q58CN9,N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),GO:0070290; GO:0016020; GO:0009395; GO:0008270,NAPE-specific phospholipase D activity; membrane; phospholipid catabolic process; zinc ion binding,PF12706;,,,,,,,,,NAPEP_BOVIN,Bos taurus (Bovine),phospholipid catabolic process [GO:0009395] comp124930_c0_seq1,1085,40.3687,0.35994462,36,103,,2.00E-50,Q3UFS4,G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75),G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75),GO:0003676,nucleic acid binding,PF13821;PF01585;,1.00E-15,CHOYP_BRAFLDRAFT_264304.1.1,,,,,,,CCD75_MOUSE,Mus musculus (Mouse), comp124934_c0_seq1,718,39.6936,0.67461859,456,2899,,4.00E-13,P83565,"39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40)","39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40)",GO:0005761,mitochondrial ribosome,PF09812;,,,,,,,,,RM40_RAT,Rattus norvegicus (Rat), comp124935_c2_seq1,362,45.0276,1.06337537,4,12,,2.00E-13,Q1RMR1,Angiopoietin-related protein 1 (Angiopoietin-like protein 1),Angiopoietin-related protein 1 (Angiopoietin-like protein 1),GO:0005615; GO:0007169,extracellular space; transmembrane receptor protein tyrosine kinase signaling pathway,PF00147;,,,,,,,,,ANGL1_BOVIN,Bos taurus (Bovine),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp124935_c2_seq2,284,45.7746,1.36988,1,11,,2.00E-15,Q9UQP3,Tenascin-N (TN-N),Tenascin-N (TN-N),GO:0007409; GO:0016049; GO:0016477; GO:0009986; GO:0007160; GO:0005578,axonogenesis; cell growth; cell migration; cell surface; cell-matrix adhesion; proteinaceous extracellular matrix,PF00147;PF00041;,,,,,,,,,TENN_HUMAN,Homo sapiens (Human),axonogenesis [GO:0007409]; cell growth [GO:0016049]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477] comp124936_c0_seq1,538,39.2193,0.83315436,22,58,,2.00E-56,Q00169,Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha),Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha),GO:0007411; GO:0005737; GO:0000062; GO:0006629; GO:0008525; GO:0035091; GO:0008526; GO:0070540; GO:0007601,axon guidance; cytoplasm; fatty-acyl-CoA binding; lipid metabolic process; phosphatidylcholine transporter activity; phosphatidylinositol binding; phosphatidylinositol transporter activity; stearic acid binding; visual perception,PF02121;,9.00E-39,CHOYP_PIPNA.1.1,,,,,,,PIPNA_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629]; visual perception [GO:0007601] comp124937_c0_seq1,486,47.5309,0.63353497,1,0,,3.00E-22,Q8BLI0,ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),GO:0008237; GO:0005578; GO:0008270,metallopeptidase activity; proteinaceous extracellular matrix; zinc ion binding,PF07679;PF08686;PF00090;,,,,,,,,,ATL1_MOUSE,Mus musculus (Mouse), comp124937_c0_seq2,773,48.1242,0.66384827,34,12,,1.00E-27,Q4VC17,A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS18_MOUSE,Mus musculus (Mouse),eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331] comp124944_c0_seq2,817,39.9021,0.15452061,4,26,,5.00E-32,Q05AV1,COMM domain-containing protein 6,COMM domain-containing protein 6,GO:0005737; GO:0005634,cytoplasm; nucleus,PF07258;,,,4.00E-31,ruditapes_c15457,,,,,COMD6_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp124946_c0_seq1,243,45.679,0.49293764,0,17,,5.00E-06,Q3UDP0,WD repeat-containing protein 41,WD repeat-containing protein 41,,,PF00400;,,,,,,,,,WDR41_MOUSE,Mus musculus (Mouse), comp124946_c2_seq1,948,45.2532,0.46313272,14,112,,4.00E-55,Q969H0,F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4),F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4),GO:0005794; GO:0007219; GO:0019005; GO:0031146; GO:0034644; GO:0005783; GO:0055088; GO:0030324; GO:0019048; GO:0032876; GO:0045746; GO:2000639; GO:2000346; GO:0010868; GO:0005730; GO:0005654; GO:0070374; GO:0045741; GO:2000060; GO:0043234; GO:0050821; GO:0016567; GO:0010883; GO:0032880; GO:0006974; GO:0003700; GO:0007062; GO:0001944; GO:0001570,Golgi apparatus; Notch signaling pathway; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular response to UV; endoplasmic reticulum; lipid homeostasis; lung development; modulation by virus of host morphology or physiology; negative regulation of DNA endoreduplication; negative regulation of Notch signaling pathway; negative regulation of SREBP signaling pathway; negative regulation of hepatocyte proliferation; negative regulation of triglyceride biosynthetic process; nucleolus; nucleoplasm; positive regulation of ERK1 and ERK2 cascade; positive regulation of epidermal growth factor-activated receptor activity; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein complex; protein stabilization; protein ubiquitination; regulation of lipid storage; regulation of protein localization; response to DNA damage stimulus; sequence-specific DNA binding transcription factor activity; sister chromatid cohesion; vasculature development; vasculogenesis,PF12937;PF00400;,1.00E-159,CHOYP_LOC584271.1.1,,,,,,,FBXW7_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of lipid storage [GO:0010883]; regulation of mitophagy [GO:1903146]; regulation of protein localization [GO:0032880]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculature development [GO:0001944]; viral process [GO:0016032] comp124950_c1_seq1,325,37.5385,0.26397011,4,56,,1.00E-12,Q5U3N0,Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8),Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8),GO:0005794; GO:0051861; GO:0046836; GO:0017089; GO:0016020; GO:0005543; GO:0015031,Golgi apparatus; glycolipid binding; glycolipid transport; glycolipid transporter activity; membrane; phospholipid binding; protein transport,PF08718;PF00169;,8.00E-18,CHOYP_LOC100370358.1.1,,,,,,,PKHA8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein transport [GO:0015031] comp124951_c1_seq1,1315,43.27,0.27693619,3,0,,6.00E-100,Q5U3K5,Rab-like protein 6 (GTP-binding protein Parf) (Rab-like protein 1) (RBEL1),Rab-like protein 6 (GTP-binding protein Parf) (Rab-like protein 1) (RBEL1),GO:0005525; GO:0005737; GO:0005634; GO:0007264,GTP binding; cytoplasm; nucleus; small GTPase mediated signal transduction,PF08477;,5.00E-104,CHOYP_RBEL1.1.1,,,,,,,RABL6_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp124951_c1_seq2,1081,41.7206,0.27678103,0,0,,3.00E-08,P36412,Ras-related protein Rab-11A,Ras-related protein Rab-11A,GO:0005525; GO:0031164; GO:0007231; GO:0045335; GO:0034394; GO:0015031; GO:0007264,GTP binding; contractile vacuolar membrane; osmosensory signaling pathway; phagocytic vesicle; protein localization to cell surface; protein transport; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RB11A_DICDI,Dictyostelium discoideum (Slime mold),cellular hypotonic response [GO:0071476]; exocytosis [GO:0006887]; osmosensory signaling pathway [GO:0007231]; protein localization to cell surface [GO:0034394]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; small GTPase mediated signal transduction [GO:0007264] comp124952_c0_seq1,666,43.5435,0.63693803,0,7,,3.00E-27,P16354,Phospholipase A2 isozymes PA3A/PA3B/PA5 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase),Phospholipase A2 isozymes PA3A/PA3B/PA5 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase),GO:0005509; GO:0005576; GO:0016042; GO:0004623; GO:0006644,calcium ion binding; extracellular region; lipid catabolic process; phospholipase A2 activity; phospholipid metabolic process,PF05826;,,,2.00E-15,ruditapes_c4017,,,,,PA23_HELSU,Heloderma suspectum (Gila monster),lipid catabolic process [GO:0016042] comp124952_c0_seq2,709,43.8646,0.59240835,0,12,,,,,,,,,2.00E-22,CHOYP_LOC100149324.1.1,3.00E-12,ruditapes_lrc33307,,,,,,, comp124968_c1_seq1,691,45.4414,0.75828081,13,49,,5.00E-09,Q32ZL2,Lipid phosphate phosphatase-related protein type 5 (EC 3.1.3.-) (Phosphatidic acid phosphatase 2d) (Plasticity-related gene 5 protein) (PRG-5),Phospholipid phosphatase-related protein type 5 (EC 3.1.3.-) (Lipid phosphate phosphatase-related protein type 5) (Phosphatidic acid phosphatase type 2d) (Plasticity-related gene 5 protein) (PRG-5),GO:0016787; GO:0016021; GO:0008152,hydrolase activity; integral to membrane; metabolic process,PF01569;,,,,,,,,,LPPR5_HUMAN,Homo sapiens (Human),phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of neuron projection development [GO:0010976]; signal transduction [GO:0007165] comp124972_c0_seq1,562,44.6619,1.17962278,53,0,,2.00E-07,Q6UVY6,DBH-like monooxygenase protein 1 (EC 1.14.17.-) (Monooxygenase X),DBH-like monooxygenase protein 1 (EC 1.14.17.-) (Monooxygenase X),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_HUMAN,Homo sapiens (Human), comp124975_c0_seq1,468,40.3846,0.37138179,4,67,,2.00E-14,O35623,BET1 homolog (mBET1) (Golgi vesicular membrane-trafficking protein p18),BET1 homolog (mBET1) (Golgi vesicular membrane-trafficking protein p18),GO:0006888; GO:0031985; GO:0000139; GO:0005801; GO:0005789; GO:0016021; GO:0015031; GO:0048280,ER to Golgi vesicle-mediated transport; Golgi cisterna; Golgi membrane; cis-Golgi network; endoplasmic reticulum membrane; integral to membrane; protein transport; vesicle fusion with Golgi apparatus,,,,9.00E-30,ruditapes_c9647,,,,,BET1_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; vesicle fusion with Golgi apparatus [GO:0048280]; vesicle-mediated transport [GO:0016192] comp124979_c0_seq2,1138,47.7153,1.150663,3093,146,,3.00E-56,A8E5W8,Protein FAM166B,Protein FAM166B,,,PF10629;,3.00E-30,CHOYP_BRAFLDRAFT_118265.1.1,,,,,,,F166B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp124981_c1_seq1,866,39.3764,0.7159382,25,114,,4.00E-15,O43734,Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2),Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2),GO:0001783; GO:0006959; GO:0048305; GO:0035556; GO:0043123,B cell apoptotic process; humoral immune response; immunoglobulin secretion; intracellular signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade,PF08357;,,,,,,,,,CIKS_HUMAN,Homo sapiens (Human),B cell apoptotic process [GO:0001783]; humoral immune response [GO:0006959]; immunoglobulin secretion [GO:0048305]; intracellular signal transduction [GO:0035556]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp124986_c0_seq1,479,48.0167,0.51126212,3,36,,2.00E-07,Q8IWY4,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0007512; GO:0007596; GO:0005509; GO:0045446; GO:0009897; GO:0005615; GO:0019897; GO:0042802; GO:0006954; GO:0009791; GO:0046982; GO:0051260,adult heart development; blood coagulation; calcium ion binding; endothelial cell differentiation; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; identical protein binding; inflammatory response; post-embryonic development; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_HUMAN,Homo sapiens (Human),adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260] comp124987_c0_seq1,1040,34.1346,0.93645271,182,19,,3.00E-10,Q8H1Y0,"Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (PDHE1-A) (EC 1.2.4.1) (Protein IAA-CONJUGATE-RESISTANT 4)","Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (PDHE1-A) (EC 1.2.4.1) (Protein IAA-CONJUGATE-RESISTANT 4)",GO:0050897; GO:0005829; GO:0006096; GO:0005759; GO:0005739; GO:0005634; GO:0004739; GO:0009651; GO:0008270,cobalt ion binding; cytosol; glycolysis; mitochondrial matrix; mitochondrion; nucleus; pyruvate dehydrogenase (acetyl-transferring) activity; response to salt stress; zinc ion binding,PF00676;,,,,,,,,,ODPA2_ARATH,Arabidopsis thaliana (Mouse-ear cress),acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]; response to salt stress [GO:0009651] comp124989_c0_seq1,884,39.9321,0.7715541,9,56,,4.00E-22,Q28997,Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor),Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor),GO:0007190; GO:0007189; GO:0004941; GO:0002032; GO:0016021; GO:0051380; GO:0005886; GO:0043410; GO:0042803; GO:0043235; GO:0006898; GO:0006940; GO:0042312,activation of adenylate cyclase activity; adenylate cyclase-activating G-protein coupled receptor signaling pathway; beta2-adrenergic receptor activity; desensitization of G-protein coupled receptor protein signaling pathway by arrestin; integral to membrane; norepinephrine binding; plasma membrane; positive regulation of MAPK cascade; protein homodimerization activity; receptor complex; receptor-mediated endocytosis; regulation of smooth muscle contraction; regulation of vasodilation,PF00001;,,,,,,,,,ADRB2_PIG,Sus scrofa (Pig),activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; desensitization of G-protein coupled receptor protein signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898]; regulation of vasodilation [GO:0042312]; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure [GO:0002025] comp124989_c0_seq2,524,39.313,0.74482443,0,0,,3.00E-09,P22270,Tyramine/octopamine receptor (Tyr/Oct-Dro),Tyramine/octopamine receptor (Tyr/Oct-Dro),GO:0008227; GO:0005887; GO:0007211; GO:0004989; GO:1900738; GO:0010578; GO:0007608,G-protein coupled amine receptor activity; integral to plasma membrane; octopamine or tyramine signaling pathway; octopamine receptor activity; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; sensory perception of smell,PF00001;,,,,,,,,,OAR_DROME,Drosophila melanogaster (Fruit fly),octopamine or tyramine signaling pathway [GO:0007211]; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900738]; regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010578]; sensory perception of smell [GO:0007608] comp124997_c1_seq1,1501,42.0386,0.46458418,1850,6455,,0,O00567,Nucleolar protein 56 (Nucleolar protein 5A),Nucleolar protein 56 (Nucleolar protein 5A),GO:0031428; GO:0008219; GO:0005737; GO:0070761; GO:0006364; GO:0030515,box C/D snoRNP complex; cell death; cytoplasm; pre-snoRNP complex; rRNA processing; snoRNA binding,PF01798;PF08156;,0,CHOYP_NOP56.1.1,4.00E-104,ruditapes2_c477,,,,,NOP56_HUMAN,Homo sapiens (Human),rRNA modification [GO:0000154]; rRNA processing [GO:0006364] comp125004_c0_seq1,1212,43.3168,0.46277361,79,260,,3.00E-86,Q5ZK44,Protein FAM172A,Protein FAM172A,GO:0005783; GO:0005576,endoplasmic reticulum; extracellular region,PF09757;,7.00E-13,CHOYP_F172A.2.2,,,,,,,F172A_CHICK,Gallus gallus (Chicken), comp125019_c0_seq1,881,39.3871,0.47362123,611,2556,,5.00E-63,P97478,Ubiquinone biosynthesis protein COQ7 homolog (Coenzyme Q biosynthesis protein 7 homolog) (Timing protein clk-1 homolog),"5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)",GO:0001306; GO:0034599; GO:0008340; GO:0001701; GO:0046872; GO:0042775; GO:0005743; GO:0005739; GO:0070584; GO:0001841; GO:0022008; GO:0005634; GO:0006744,age-dependent response to oxidative stress; cellular response to oxidative stress; determination of adult lifespan; in utero embryonic development; metal ion binding; mitochondrial ATP synthesis coupled electron transport; mitochondrial inner membrane; mitochondrion; mitochondrion morphogenesis; neural tube formation; neurogenesis; nucleus; ubiquinone biosynthetic process,PF03232;,9.00E-48,CHOYP_LOC100377736.1.1,3.00E-70,ruditapes2_c420,,,,,COQ7_MOUSE,Mus musculus (Mouse),age-dependent response to oxidative stress [GO:0001306]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; in utero embryonic development [GO:0001701]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrion morphogenesis [GO:0070584]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube formation [GO:0001841]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of reactive oxygen species metabolic process [GO:2000377]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; ubiquinone biosynthetic process [GO:0006744] comp125022_c1_seq2,575,50.2609,1.13702799,2,74,,7.00E-06,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp125027_c1_seq1,325,42.1538,0.62532561,5,17,,1.00E-18,Q86VR2,Protein FAM134C,Protein FAM134C,GO:0016021,integral to membrane,,,,,,,,,,F134C_HUMAN,Homo sapiens (Human),positive regulation of neuron projection development [GO:0010976] comp125029_c0_seq1,414,37.1981,0.84008587,0,51,,8.00E-11,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp125029_c2_seq1,231,43.7229,1.65062382,0,41,,2.00E-08,Q5XJP0,"Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B (EC 2.4.1.206) (Lactotriaosylceramide synthase B) (Lc(3)Cer synthase B) (Lc3 synthase B) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5B) (BGnT-5B) (Beta-1,3-Gn-T5B) (Beta-1,3-N-acetylglucosaminyltransferase 5B) (Beta3Gn-T5B)","Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B (EC 2.4.1.206) (Lactotriaosylceramide synthase B) (Lc(3)Cer synthase B) (Lc3 synthase B) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5B) (BGnT-5B) (Beta-1,3-Gn-T5B) (Beta-1,3-N-acetylglucosaminyltransferase 5B) (Beta3Gn-T5B)",GO:0000139; GO:0008378; GO:0016021; GO:0047256; GO:0006486,"Golgi membrane; galactosyltransferase activity; integral to membrane; lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity; protein glycosylation",PF01762;,,,,,,,,,B3G5B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein glycosylation [GO:0006486] comp125030_c0_seq1,1525,47.2787,0.7680339,96,8,,0,Q8BTY2,Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7),Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7),GO:0016324; GO:0060117; GO:0016323; GO:0021747; GO:0005737; GO:0005452; GO:0016021; GO:0061299; GO:0046666; GO:0006814; GO:0032420; GO:0015293,apical plasma membrane; auditory receptor cell development; basolateral plasma membrane; cochlear nucleus development; cytoplasm; inorganic anion exchanger activity; integral to membrane; retina vasculature morphogenesis in camera-type eye; retinal cell programmed cell death; sodium ion transport; stereocilium; symporter activity,PF07565;PF00955;,2.00E-65,CHOYP_S4A10.2.4,,,,,,,S4A7_MOUSE,Mus musculus (Mouse),anion transmembrane transport [GO:0098656]; auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cochlear nucleus development [GO:0021747]; regulation of intracellular pH [GO:0051453]; retinal cell programmed cell death [GO:0046666]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sodium ion transport [GO:0006814]; visual perception [GO:0007601] comp125034_c0_seq1,433,44.8037,0.87677235,3,0,,1.00E-44,P0CR76,RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) (Suppressor of SUA7 protein 2 homolog),RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) (Suppressor of SUA7 protein 2 homolog),GO:0006397; GO:0005634; GO:0004721,mRNA processing; nucleus; phosphoprotein phosphatase activity,PF04722;,,,,,,,,,SSU72_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),mRNA processing [GO:0006397]; negative regulation of chromosome condensation [GO:1902340] comp125034_c0_seq3,641,40.8736,1.047555,16,17,,7.00E-83,Q5ZJQ7,RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16),RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16),GO:0008420; GO:0005737; GO:0070940; GO:0006378; GO:0005634,CTD phosphatase activity; cytoplasm; dephosphorylation of RNA polymerase II C-terminal domain; mRNA polyadenylation; nucleus,PF04722;,7.00E-48,CHOYP_SSU72.1.1,,,,,,,SSU72_CHICK,Gallus gallus (Chicken),dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA polyadenylation [GO:0006378] comp125035_c0_seq1,405,37.5309,0.49340579,23,0,,7.00E-12,Q9CQY7,Monocyte to macrophage differentiation factor (Progestin and adipoQ receptor family member XI),Monocyte to macrophage differentiation factor (Progestin and adipoQ receptor family member XI),GO:0019835; GO:0016021; GO:0031902; GO:0005765,cytolysis; integral to membrane; late endosome membrane; lysosomal membrane,PF03006;,2.00E-19,CHOYP_LOC659403.1.1,,,,,,,PAQRB_MOUSE,Mus musculus (Mouse),cytolysis [GO:0019835]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase activity [GO:0045860]; regulation of protein localization [GO:0032880] comp125036_c0_seq1,1235,36.6802,0.80446583,0,301,,6.00E-46,Q08E40,Zinc transporter ZIP12 (Solute carrier family 39 member 12) (Zrt- and Irt-like protein 12) (ZIP-12),Zinc transporter ZIP12 (Solute carrier family 39 member 12) (Zrt- and Irt-like protein 12) (ZIP-12),GO:0016021; GO:0046873; GO:0006829,integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,9.00E-18,CHOYP_LOC100367064.1.1,5.00E-44,ruditapes_c24556,,,,,S39AC_BOVIN,Bos taurus (Bovine),cellular zinc ion homeostasis [GO:0006882]; regulation of microtubule polymerization [GO:0031113]; regulation of neuron projection development [GO:0010975]; signal transduction [GO:0007165]; zinc II ion transmembrane import [GO:0071578] comp125040_c0_seq2,1055,40.5687,1.0923747,18,67,,1.00E-86,Q95NM6,"Endonuclease G, mitochondrial (Endo G) (EC 3.1.30.-) (Ced-3 protease suppressor 6)","Endonuclease G, mitochondrial (Endo G) (EC 3.1.30.-) (Ced-3 protease suppressor 6)",GO:0006401; GO:0006309; GO:0004520; GO:0004521; GO:0046872; GO:0005739; GO:0043565,RNA catabolic process; apoptotic DNA fragmentation; endodeoxyribonuclease activity; endoribonuclease activity; metal ion binding; mitochondrion; sequence-specific DNA binding,PF01223;,7.00E-31,CHOYP_DVIR_GJ19936.1.1,,,,,,,NUCG_CAEEL,Caenorhabditis elegans,"apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; DNA catabolic process, endonucleolytic [GO:0000737]; RNA catabolic process [GO:0006401]" comp125042_c0_seq1,1327,45.3655,0.51397765,89,44,,2.00E-138,P45844,ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog),ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog),GO:0043531; GO:0005524; GO:0005794; GO:0000139; GO:0042987; GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0009720; GO:0005789; GO:0009897; GO:0034436; GO:0034437; GO:0034375; GO:0005887; GO:0032367; GO:0042157; GO:0034374; GO:0005739; GO:0010887; GO:0010745; GO:0005543; GO:0033700; GO:0055091; GO:0005548; GO:0045542; GO:0010875; GO:0042803; GO:0055037; GO:0010872; GO:0006355; GO:0055099; GO:0033993; GO:0043691; GO:0034041; GO:0019534,"ADP binding; ATP binding; Golgi apparatus; Golgi membrane; amyloid precursor protein catabolic process; cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; detection of hormone stimulus; endoplasmic reticulum membrane; external side of plasma membrane; glycoprotein transport; glycoprotein transporter activity; high-density lipoprotein particle remodeling; integral to plasma membrane; intracellular cholesterol transport; lipoprotein metabolic process; low-density lipoprotein particle remodeling; mitochondrion; negative regulation of cholesterol storage; negative regulation of macrophage derived foam cell differentiation; phospholipid binding; phospholipid efflux; phospholipid homeostasis; phospholipid transporter activity; positive regulation of cholesterol biosynthetic process; positive regulation of cholesterol efflux; protein homodimerization activity; recycling endosome; regulation of cholesterol esterification; regulation of transcription, DNA-dependent; response to high density lipoprotein particle stimulus; response to lipid; reverse cholesterol transport; sterol-transporting ATPase activity; toxin transporter activity",PF01061;PF00005;,9.00E-88,CHOYP_ABCG1.1.1,,,,,,,ABCG1_HUMAN,Homo sapiens (Human),"amyloid precursor protein catabolic process [GO:0042987]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; detection of hormone stimulus [GO:0009720]; glycoprotein transport [GO:0034436]; high-density lipoprotein particle remodeling [GO:0034375]; intracellular cholesterol transport [GO:0032367]; lipoprotein metabolic process [GO:0042157]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol efflux [GO:0010875]; regulation of cholesterol esterification [GO:0010872]; regulation of transcription, DNA-templated [GO:0006355]; response to high density lipoprotein particle [GO:0055099]; response to lipid [GO:0033993]; response to organic substance [GO:0010033]; reverse cholesterol transport [GO:0043691]; transmembrane transport [GO:0055085]" comp125042_c0_seq2,635,43.622,0.76338776,0,9,,,,,,,,,3.00E-33,CHOYP_LOC100756677.1.1,,,,,,,,, comp125050_c0_seq1,1590,42.2013,0.97711654,790,4332,,8.00E-121,Q5T6V5,UPF0553 protein C9orf64,UPF0553 protein C9orf64,,,PF10343;,1.00E-24,CHOYP_CI064.1.1,,,,,,,CI064_HUMAN,Homo sapiens (Human),tRNA modification [GO:0006400] comp125053_c0_seq1,1072,40.7649,0.58693142,3,0,,2.00E-59,Q9Y4B6,Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Vpr-interacting protein),Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein),GO:0005737; GO:0019048; GO:0005634; GO:0016567,cytoplasm; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination,,2.00E-19,CHOYP_VPRBP.1.1,,,,,,,VPRBP_HUMAN,Homo sapiens (Human),"B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; histone H2A-T120 phosphorylation [GO:1990245]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]; V(D)J recombination [GO:0033151]; viral process [GO:0016032]" comp125053_c0_seq4,1086,40.6077,0.56102694,0,0,,,,,,,,,2.00E-19,CHOYP_VPRBP.1.1,,,,,,,,, comp125059_c0_seq1,862,47.7958,0.57599238,19,49,,2.00E-68,Q9NZI7,Upstream-binding protein 1 (Transcription factor LBP-1),Upstream-binding protein 1 (Transcription factor LBP-1),GO:0003677; GO:0001525; GO:0045892; GO:0005634; GO:0006357; GO:0003700; GO:0003714; GO:0006351; GO:0019079,"DNA binding; angiogenesis; negative regulation of transcription, DNA-dependent; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; transcription, DNA-dependent; viral genome replication",PF04516;,5.00E-76,CHOYP_TFCP2.1.2,,,,,,,UBIP1_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]" comp125060_c0_seq1,662,43.3535,0.65256054,35,19,,2.00E-54,Q9QY06,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0005524; GO:0005096; GO:0005100; GO:0007266; GO:0005938; GO:0030010; GO:0032433; GO:0035556; GO:0030027; GO:0072673; GO:0048246; GO:0046872; GO:0000146; GO:0002548; GO:0016459; GO:0048471; GO:0043547; GO:0001726,ATP binding; GTPase activator activity; Rho GTPase activator activity; Rho protein signal transduction; cell cortex; establishment of cell polarity; filopodium tip; intracellular signal transduction; lamellipodium; lamellipodium morphogenesis; macrophage chemotaxis; metal ion binding; microfilament motor activity; monocyte chemotaxis; myosin complex; perinuclear region of cytoplasm; positive regulation of GTPase activity; ruffle,PF00612;PF00063;PF00788;PF00620;,2.00E-41,CHOYP_MYO9.5.5,,,,,,,MYO9B_MOUSE,Mus musculus (Mouse),actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp125066_c0_seq1,725,40,0.7702561,41,29,,1.00E-07,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp125070_c0_seq1,341,46.0411,0.501144,24,16,,7.00E-38,Q5REW9,Ankyrin repeat domain-containing protein 27,Ankyrin repeat domain-containing protein 27,GO:0005096; GO:0005737; GO:0043547,GTPase activator activity; cytoplasm; positive regulation of GTPase activity,PF12796;PF02204;,4.00E-16,CHOYP_ANKRD27.1.1,,,,,,,ANR27_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp125070_c1_seq1,411,43.309,0.15893112,17,20,,1.00E-09,Q96NW4,Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein),Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein),GO:0005096; GO:0005769; GO:0045022; GO:0005085; GO:0005764; GO:0043547,GTPase activator activity; early endosome; early endosome to late endosome transport; guanyl-nucleotide exchange factor activity; lysosome; positive regulation of GTPase activity,PF12796;PF13606;PF02204;,,,,,,,,,ANR27_HUMAN,Homo sapiens (Human),"early endosome to late endosome transport [GO:0045022]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp125078_c0_seq1,774,43.2817,0.36025949,5,19,,3.00E-10,A4IG66,Transmembrane protein 201,Transmembrane protein 201,GO:0016021,integral to membrane,PF10476;PF09779;,,,,,,,,,TM201_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nuclear migration along microtubule [GO:0030473] comp125091_c0_seq2,1365,46.5934,0.28715018,44,61,,4.00E-20,Q4V7B8,RING finger protein 44,RING finger protein 44,GO:0008270,zinc ion binding,PF13639;,,,,,,,,,RNF44_RAT,Rattus norvegicus (Rat),"proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of transcription, DNA-templated [GO:0006355]" comp125092_c0_seq1,1437,45.5115,0.43248141,42,27,,1.00E-24,Q6NRS1,Inhibitor of Bruton tyrosine kinase (IBtk),Inhibitor of Bruton tyrosine kinase (IBtk),GO:0005737; GO:0016020,cytoplasm; membrane,PF12796;PF00651;PF00415;,,,,,,,,,IBTK_XENLA,Xenopus laevis (African clawed frog), comp125104_c0_seq1,1091,36.3886,0.59100096,43,271,,1.00E-56,Q8VBT0,Thioredoxin-related transmembrane protein 1 (Thioredoxin domain-containing protein 1),Thioredoxin-related transmembrane protein 1 (Thioredoxin domain-containing protein 1),GO:0045454; GO:0015036; GO:0005789; GO:0016021; GO:0043066,cell redox homeostasis; disulfide oxidoreductase activity; endoplasmic reticulum membrane; integral to membrane; negative regulation of apoptotic process,PF00085;,3.00E-43,CHOYP_BRAFLDRAFT_275793.1.1,,,,,,,TMX1_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp125109_c0_seq1,1171,42.4424,0.49390596,129,39,,8.00E-28,Q800K6,DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP),DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP),GO:0003677; GO:0006281; GO:0000076; GO:0006270; GO:0071165; GO:0000785; GO:0003682; GO:0005737; GO:0005815; GO:0005634; GO:0035563; GO:0033138; GO:0045860; GO:0071168; GO:0030174; GO:0006974; GO:0000922,DNA binding; DNA repair; DNA replication checkpoint; DNA replication initiation; GINS complex assembly; chromatin; chromatin binding; cytoplasm; microtubule organizing center; nucleus; positive regulation of chromatin binding; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase activity; protein localization to chromatin; regulation of DNA-dependent DNA replication initiation; response to DNA damage stimulus; spindle pole,PF00533;PF12738;,,,,,,,,,TOB1A_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp125110_c0_seq1,310,52.2581,0.77544831,9,29,,,,,,,,,2.00E-26,CHOYP_contig_055041,,,,,,,,, comp125113_c0_seq1,563,40.8526,0.9438232,98,129,,1.00E-47,Q5R4W3,DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17),DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17),GO:0005671; GO:0003887; GO:0008622; GO:0043966; GO:0043565,Ada2/Gcn5/Ada3 transcription activator complex; DNA-directed DNA polymerase activity; epsilon DNA polymerase complex; histone H3 acetylation; sequence-specific DNA binding,PF00808;,2.00E-60,CHOYP_DPOE3.1.2,,,7.00E-62,AM856760.p.cg.6,9,,DPOE3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),histone H3 acetylation [GO:0043966] comp125114_c0_seq1,1244,39.7106,0.37245736,40,217,,1.00E-83,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,2.00E-39,CHOYP_LOC100369194.1.1,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp125123_c0_seq1,1497,39.3454,0.76766864,86,6052,,7.00E-97,Q71R50,Dehydrogenase/reductase SDR family member 11 (EC 1.-.-.-),Dehydrogenase/reductase SDR family member 11 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 24C member 1),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF00106;,,,,,,,,,DHR11_CHICK,Gallus gallus (Chicken), comp125145_c0_seq2,984,44.3089,0.43558418,18,89,,4.00E-24,Q008S8,Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH),Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH),GO:0005089; GO:0035023,Rho guanyl-nucleotide exchange factor activity; regulation of Rho protein signal transduction,PF14252;PF12937;PF00621;,9.00E-17,CHOYP_LOC100486001.1.1,,,,,,,ECT2L_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp125145_c0_seq3,443,43.3409,0.33757096,0,0,,2.00E-33,Q8IX29,F-box only protein 16,F-box only protein 16,,,PF12937;,4.00E-17,CHOYP_LOC100486001.1.1,,,,,,,FBX16_HUMAN,Homo sapiens (Human), comp125158_c0_seq3,704,44.4602,0.58784409,4,27,,9.00E-34,Q69ZU8,Ankyrin repeat domain-containing protein 6 (Diversin),Ankyrin repeat domain-containing protein 6 (Diversin),GO:0005737; GO:0090090; GO:0005634; GO:0046330; GO:2000096,"cytoplasm; negative regulation of canonical Wnt receptor signaling pathway; nucleus; positive regulation of JNK cascade; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway",PF12796;,,,,,,,,,ANKR6_MOUSE,Mus musculus (Mouse),"negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]" comp125158_c1_seq1,837,46.595,0.75375769,1,13,,8.00E-14,Q0V8G2,GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2),GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2),GO:0005634; GO:0045944; GO:0044212; GO:0006351,"nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00023;PF12796;,1.00E-52,CHOYP_ANKRD6.1.2,,,,,,,GABP2_BOVIN,Bos taurus (Bovine),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp125160_c0_seq1,592,44.0878,0.59300169,9,69,,,,,,,,,2.00E-41,CHOYP_LOC100533356.1.6,2.00E-38,ruditapes_c18123,,,,,,, comp125160_c1_seq1,494,44.9393,0.80377044,0,33,,1.00E-27,Q23027,Innexin-5 (Protein opu-5),Innexin-5 (Protein opu-5),GO:0005921; GO:0055077; GO:0016021; GO:0006811; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transport; plasma membrane,PF00876;,,,,,,,,,INX5_CAEEL,Caenorhabditis elegans,ion transport [GO:0006811] comp125160_c1_seq2,426,45.7746,0.80871658,0,5,,2.00E-37,Q03412,Innexin unc-7 (Uncoordinated protein 7),Innexin unc-7 (Uncoordinated protein 7),GO:0005921; GO:0016264; GO:0055077; GO:0016021; GO:0034220; GO:0040011; GO:0032589; GO:0018991; GO:0043051; GO:0042221,gap junction; gap junction assembly; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; locomotion; neuron projection membrane; oviposition; regulation of pharyngeal pumping; response to chemical stimulus,PF00876;,,,,,,,,,UNC7_CAEEL,Caenorhabditis elegans,gap junction assembly [GO:0016264]; ion transmembrane transport [GO:0034220]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of pharyngeal pumping [GO:0043051]; response to anesthetic [GO:0072347] comp125161_c0_seq1,847,47.1074,0.55110818,6,38,,2.00E-19,Q9QZZ4,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,,,,,,,,,MYO15_MOUSE,Mus musculus (Mouse),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp125161_c0_seq2,336,45.8333,0.69377866,0,0,,,,,,,,,2.00E-13,CHOYP_LOC100901924.3.3,,,,,,,,, comp125161_c0_seq3,536,48.1343,0.49993967,0,0,,,,,,,,,3.00E-13,CHOYP_MYO15.1.1,,,,,,,,, comp125166_c1_seq1,378,41.0053,0.44708773,6,35,,2.00E-09,Q4VA36,Coiled-coil domain-containing protein 84,Coiled-coil domain-containing protein 84,,,PF14968;,,,,,,,,,CCD84_MOUSE,Mus musculus (Mouse), comp125168_c1_seq2,1046,31.1663,0.55776307,114,1,,,,,,,,,,,4.00E-19,ruditapes2_c2959,,,,,,, comp125171_c0_seq2,359,43.454,0.96596423,0,0,,,,,,,,,4.00E-28,CHOYP_LOC100215960.1.1,8.00E-29,ruditapes2_c1900,,,,,,, comp125173_c0_seq1,1260,42.8571,0.43265563,50,97,,2.00E-162,Q9R1S8,Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH),Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH),GO:0004198; GO:0005634; GO:0097264,calcium-dependent cysteine-type endopeptidase activity; nucleus; self proteolysis,PF01067;PF04212;PF00648;,2.00E-134,CHOYP_CAPN7.2.2,,,,,,,CAN7_MOUSE,Mus musculus (Mouse),positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264] comp125175_c0_seq3,670,40.597,0.4820413,7,37,,1.00E-59,Q0VD27,"Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase) (MASA homolog)","Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase) (MASA homolog)",GO:0019509; GO:0043874; GO:0005737; GO:0000287; GO:0005634,L-methionine salvage from methylthioadenosine; acireductone synthase activity; cytoplasm; magnesium ion binding; nucleus,,1.00E-37,CHOYP_ENOPH.3.4,,,,,,,ENOPH_BOVIN,Bos taurus (Bovine),L-methionine biosynthetic process from methylthioadenosine [GO:0019509] comp125176_c0_seq1,656,47.7134,0.32431174,47,12,,6.00E-23,Q8IVV2,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp125177_c0_seq1,1022,33.6595,0.62547614,425,3710,,2.00E-21,Q96MD7,Uncharacterized protein C9orf85,Uncharacterized protein C9orf85,,,PF10217;,6.00E-19,CHOYP_LOC100650709.1.1,1.00E-31,ruditapes_c15605,,,,,CI085_HUMAN,Homo sapiens (Human), comp125190_c1_seq1,1246,46.3884,0.4938617,52,56,,4.00E-65,Q6ZQK0,Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3),Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3),GO:0051301; GO:0042585; GO:0007076; GO:0000799,cell division; germinal vesicle; mitotic chromosome condensation; nuclear condensin complex,PF12717;,1.00E-22,CHOYP_LOC100367618.1.1,,,,,,,CNDD3_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076] comp125203_c1_seq1,601,44.7587,0.80805593,0,0,,,,,,,,,5.00E-30,CHOYP_LOC579332.1.1,,,,,,,,, comp125203_c1_seq2,748,45.4545,0.71060249,19,4,,2.00E-25,Q92538,Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),GO:0005086; GO:0048205; GO:0000139; GO:0005795; GO:0005801; GO:0005788; GO:0005739; GO:0019048; GO:0005777; GO:0006892; GO:0032012; GO:0006890; GO:0005802,"ARF guanyl-nucleotide exchange factor activity; COPI coating of Golgi vesicle; Golgi membrane; Golgi stack; cis-Golgi network; endoplasmic reticulum lumen; mitochondrion; modulation by virus of host morphology or physiology; peroxisome; post-Golgi vesicle-mediated transport; regulation of ARF protein signal transduction; retrograde vesicle-mediated transport, Golgi to ER; trans-Golgi network",PF01369;PF12783;,,,,,,,,,GBF1_HUMAN,Homo sapiens (Human),"cell activation involved in immune response [GO:0002263]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]" comp125203_c2_seq1,418,49.0431,0.47913367,21,30,,5.00E-28,Q9R1D7,Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),GO:0005086; GO:0032012,ARF guanyl-nucleotide exchange factor activity; regulation of ARF protein signal transduction,PF01369;PF12783;,2.00E-26,CHOYP_GBF1.1.1,,,,,,,GBF1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] comp125209_c0_seq1,1433,41.7306,0.53170215,0,0,,5.00E-132,Q6PDL0,"Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)","Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)",GO:0005524; GO:0005813; GO:0051642; GO:0005868; GO:0005874; GO:0000226; GO:0003777; GO:0007018; GO:0006810,ATP binding; centrosome; centrosome localization; cytoplasmic dynein complex; microtubule; microtubule cytoskeleton organization; microtubule motor activity; microtubule-based movement; transport,PF05783;,7.00E-115,CHOYP_BRAFLDRAFT_80039.1.1,,,,,,,DC1L2_MOUSE,Mus musculus (Mouse),centrosome localization [GO:0051642]; microtubule-based movement [GO:0007018]; microtubule cytoskeleton organization [GO:0000226]; transport [GO:0006810] comp125209_c0_seq3,1191,40.806,0.48547414,0,0,,,,,,,,,5.00E-21,CHOYP_DC1L1.1.1,,,,,,,,, comp125209_c0_seq4,852,39.554,0.60820048,0,0,,2.00E-112,Q6PDL0,"Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)","Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)",GO:0005524; GO:0005813; GO:0051642; GO:0005868; GO:0005874; GO:0000226; GO:0003777; GO:0007018; GO:0006810,ATP binding; centrosome; centrosome localization; cytoplasmic dynein complex; microtubule; microtubule cytoskeleton organization; microtubule motor activity; microtubule-based movement; transport,PF05783;,,,,,,,,,DC1L2_MOUSE,Mus musculus (Mouse),centrosome localization [GO:0051642]; microtubule-based movement [GO:0007018]; microtubule cytoskeleton organization [GO:0000226]; transport [GO:0006810] comp125215_c1_seq1,720,45.1389,0.52294344,1268,3324,,3.00E-34,O35680,"28S ribosomal protein S12, mitochondrial (MRP-S12) (S12mt) (MT-RPS12)","28S ribosomal protein S12, mitochondrial (MRP-S12) (S12mt) (MT-RPS12)",GO:0005739; GO:0015935; GO:0003735; GO:0006412,mitochondrion; small ribosomal subunit; structural constituent of ribosome; translation,PF00164;,4.00E-32,CHOYP_AGAP_AGAP013102.1.1,5.00E-35,ruditapes_c10140,,,,,RT12_MOUSE,Mus musculus (Mouse),mitochondrial translation [GO:0032543]; translation [GO:0006412] comp125220_c0_seq1,515,47.1845,0.3553243,0,11,,2.00E-24,P54797,Transport and Golgi organization 2 homolog (Ser/Thr-rich protein T10 in DGCR region),Transport and Golgi organization 2 homolog (Ser/Thr-rich protein T10 in DGCR region),GO:0005739,mitochondrion,PF05742;,,,,,,,,,T10_MOUSE,Mus musculus (Mouse), comp125223_c1_seq1,1034,45.9381,0.38594752,64,40,,5.00E-25,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp125223_c2_seq1,248,42.7419,0.88930017,6,0,,1.00E-14,Q9W6R5,Retinoschisin (X-linked juvenile retinoschisis protein homolog),Retinoschisin (X-linked juvenile retinoschisis protein homolog),GO:0007155; GO:0005576,cell adhesion; extracellular region,PF00754;,,,,,,,,,XLRS1_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),cell adhesion [GO:0007155] comp125225_c0_seq2,2409,42.7978,0.88547545,26,54,,1.00E-36,Q62504,Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog),Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog),GO:0007219; GO:0003723; GO:0045892; GO:0000166; GO:0005634; GO:0045893; GO:0003700; GO:0003697; GO:0003714; GO:0006351,"Notch signaling pathway; RNA binding; negative regulation of transcription, DNA-dependent; nucleotide binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription corepressor activity; transcription, DNA-dependent",PF00076;PF07744;,,,,,,,,,MINT_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp125227_c0_seq2,504,39.0873,0.7980436,19,46,,6.00E-28,Q0V9G5,Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44),Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44),GO:0051322; GO:0051301; GO:0007067; GO:0060564; GO:0005634; GO:0016579; GO:0090231; GO:0004221; GO:0006511; GO:0004843; GO:0008270,anaphase; cell division; mitosis; negative regulation of mitotic anaphase-promoting complex activity; nucleus; protein deubiquitination; regulation of spindle checkpoint; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding,PF00443;PF02148;,5.00E-29,CHOYP_LOC100375318.1.1,,,,,,,UBP44_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; protein deubiquitination [GO:0016579]; regulation of spindle checkpoint [GO:0090231]; ubiquitin-dependent protein catabolic process [GO:0006511] comp125238_c0_seq1,1031,33.4627,0.69434231,968,5067,,,,,,,,,,,6.00E-11,ruditapes2_c208,,,,,,, comp125240_c0_seq1,1045,44.0191,0.57657197,43,36,,1.00E-46,Q91ZX7,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0005887; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0048471; GO:0010875; GO:0006898; GO:0032956; GO:0032429,aorta morphogenesis; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; integral to plasma membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; perinuclear region of cytoplasm; positive regulation of cholesterol efflux; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429] comp125246_c0_seq2,290,49.6552,0.46672568,4,17,,7.00E-31,Q6NYL3,"Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]","Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]",GO:0003857; GO:0050662; GO:0004165; GO:0004300; GO:0006635; GO:0005777,3-hydroxyacyl-CoA dehydrogenase activity; coenzyme binding; dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; fatty acid beta-oxidation; peroxisome,PF00725;PF02737;PF00378;,,,,,,,,,ECHP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid beta-oxidation [GO:0006635] comp125256_c0_seq1,683,47.877,1.06420993,27,106,,4.00E-11,Q90610,Neogenin (Fragment),Neogenin (Fragment),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;PF06583;,,,,,,,,,NEO1_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; positive regulation of BMP signaling pathway [GO:0030513] comp125259_c0_seq1,1215,48.7243,0.62575088,3,0,,5.00E-114,Q8CGF6,WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin),WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin),GO:0005737; GO:0005874; GO:0007275,cytoplasm; microtubule; multicellular organismal development,PF12894;PF00400;,,,,,,,,,WDR47_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275] comp125259_c0_seq2,1263,46.8725,0.59149051,3,0,,2.00E-11,Q7ZUV2,Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),GO:0051301; GO:0008352; GO:0005874; GO:0051013; GO:0007067; GO:0000922,cell division; katanin complex; microtubule; microtubule severing; mitosis; spindle pole,PF13925;PF00400;,,,,,,,,,KTNB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),brain development [GO:0007420]; cell division [GO:0051301]; microtubule severing [GO:0051013]; midbrain development [GO:0030901]; mitotic nuclear division [GO:0007067] comp125259_c0_seq3,1073,48.3691,0.60670803,0,0,,2.00E-114,O94967,WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin),WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin),GO:0005737; GO:0005874; GO:0007275,cytoplasm; microtubule; multicellular organismal development,PF12894;PF00400;,2.00E-82,CHOYP_WDR47.1.1,,,,,,,WDR47_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp125272_c0_seq1,830,32.7711,0.35950734,1951,211,,8.00E-21,Q9D581,EF-hand calcium-binding domain-containing protein 10,EF-hand calcium-binding domain-containing protein 10,GO:0005509,calcium ion binding,,5.00E-13,CHOYP_LOC100375122.1.1,,,,,,,EFC10_MOUSE,Mus musculus (Mouse), comp125278_c0_seq2,617,31.4425,0.40814637,3,50,,1.00E-08,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,9.00E-40,CHOYP_LOC100562878.2.2,2.00E-14,ruditapes_c19911,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp125284_c1_seq2,687,43.377,0.63774699,2,1,,3.00E-28,Q96XY5,Uncharacterized protein STK_23830,Uncharacterized protein STK_23830,,,PF01661;,,,,,,,,,Y2383_SULTO,Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7), comp125284_c1_seq6,506,40.9091,0.67781013,7,5,,1.00E-06,P0C6F5,Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)],Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)],GO:0003723; GO:0003968; GO:0004197; GO:0033644; GO:0044220; GO:0016817; GO:0016788; GO:0039595; GO:0039520; GO:0016021; GO:0039648; GO:0008242; GO:0006508; GO:0039548; GO:0039579; GO:0039604; GO:0039501; GO:0039502; GO:0019079; GO:0019082; GO:0008270,"RNA binding; RNA-directed RNA polymerase activity; cysteine-type endopeptidase activity; host cell membrane; host cell perinuclear region of cytoplasm; hydrolase activity, acting on acid anhydrides; hydrolase activity, acting on ester bonds; induction by virus of catabolism of host mRNA; induction by virus of host autophagy; integral to membrane; modulation by virus of host protein ubiquitination; omega peptidase activity; proteolysis; suppression by virus of host IRF3 activity; suppression by virus of host ISG15 activity; suppression by virus of host translation; suppression by virus of host type I interferon production; suppression by virus of host type I interferon-mediated signaling pathway; viral genome replication; viral protein processing; zinc ion binding",PF16348;PF12379;PF01661;PF16251;PF11501;PF09401;PF12124;PF08716;PF08717;PF08710;PF05409;PF11633;PF08715;,,,,,,,,,R1A_BC279,Bat coronavirus 279/2005 (BtCoV) (BtCoV/279/2005),induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082] comp125288_c2_seq1,572,44.7552,0.91130692,0,192,,6.00E-09,Q8TE56,A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAM-TS 17) (ADAM-TS17) (ADAMTS-17) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAM-TS 17) (ADAM-TS17) (ADAMTS-17) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS17_HUMAN,Homo sapiens (Human), comp125290_c0_seq1,614,47.557,0.34857451,14,34,,4.00E-79,A2BFP5,Solute carrier family 12 member 9,Solute carrier family 12 member 9,GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF00324;PF03522;,2.00E-93,CHOYP_S12A9.1.1,,,,,,,S12A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp125290_c1_seq3,822,46.5937,0.70928657,3,0,,8.00E-19,Q09573,Sodium/chloride cotransporter 3,Sodium/chloride cotransporter 3,GO:0016021; GO:0006813; GO:0006814; GO:0015293,integral to membrane; potassium ion transport; sodium ion transport; symporter activity,PF00324;PF03522;,,,,,,,,,KCC3_CAEEL,Caenorhabditis elegans,chemical synaptic transmission [GO:0007268]; microvillus organization [GO:0032528]; negative regulation of guanylate cyclase activity [GO:0031283]; sodium ion transport [GO:0006814] comp125291_c0_seq1,1210,43.6364,0.82235796,0,0,,4.00E-93,Q9H0K1,Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2),Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2),GO:0005524; GO:0005794; GO:0008286; GO:0007243; GO:0000287; GO:0005634; GO:0046777; GO:0004674; GO:0046626,ATP binding; Golgi apparatus; insulin receptor signaling pathway; intracellular protein kinase cascade; magnesium ion binding; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; regulation of insulin receptor signaling pathway,PF00069;,9.00E-31,CHOYP_SIK3.1.1,,,,,,,SIK2_HUMAN,Homo sapiens (Human),cellular response to hormone stimulus [GO:0032870]; intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] comp125291_c0_seq2,1430,43.6364,0.81374951,12,14,,9.00E-71,Q60670,Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (HRT-20) (Myocardial SNF1-like kinase) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK),Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (HRT-20) (Myocardial SNF1-like kinase) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK),GO:0071889; GO:0005524; GO:0043276; GO:0008140; GO:0055007; GO:0007049; GO:0005737; GO:0005829; GO:0007243; GO:0000287; GO:0032792; GO:0045721; GO:0000122; GO:0010868; GO:0005634; GO:2000210; GO:0046777; GO:0004674; GO:0007346; GO:0010830; GO:0002028,14-3-3 protein binding; ATP binding; anoikis; cAMP response element binding protein binding; cardiac muscle cell differentiation; cell cycle; cytoplasm; cytosol; intracellular protein kinase cascade; magnesium ion binding; negative regulation of CREB transcription factor activity; negative regulation of gluconeogenesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of triglyceride biosynthetic process; nucleus; positive regulation of anoikis; protein autophosphorylation; protein serine/threonine kinase activity; regulation of mitotic cell cycle; regulation of myotube differentiation; regulation of sodium ion transport,PF00069;,2.00E-96,CHOYP_SIK2.1.1,,,,,,,SIK1_MOUSE,Mus musculus (Mouse),anoikis [GO:0043276]; cardiac muscle cell differentiation [GO:0055007]; cell cycle [GO:0007049]; cellular response to hormone stimulus [GO:0032870]; entrainment of circadian clock by photoperiod [GO:0043153]; intracellular signal transduction [GO:0035556]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of triglyceride biosynthetic process [GO:0010868]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of mitotic cell cycle [GO:0007346]; regulation of myotube differentiation [GO:0010830]; regulation of sodium ion transport [GO:0002028]; rhythmic process [GO:0048511] comp125293_c0_seq1,422,45.9716,0.45192561,13,14,,2.00E-29,Q9XTA5,Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha),Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha),GO:0019896; GO:0071456; GO:0005737; GO:0035035; GO:0005634; GO:0045893; GO:0003700; GO:0004871; GO:0044212; GO:0006351,"axon transport of mitochondrion; cellular response to hypoxia; cytoplasm; histone acetyltransferase binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription regulatory region DNA binding; transcription, DNA-dependent",PF11413;PF08778;PF00989;PF08447;,2.00E-20,CHOYP_LOC101067536.1.1,,,,,,,HIF1A_BOVIN,Bos taurus (Bovine),"axonal transport of mitochondrion [GO:0019896]; cellular response to hypoxia [GO:0071456]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor production [GO:0010575]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp125298_c0_seq1,695,43.741,0.63272858,23,46,,,,,,,,,6.00E-17,CHOYP_FACR1.1.2,,,,,,,,, comp125298_c0_seq3,1145,41.8341,0.55226001,45,22,,2.00E-126,Q7ZXF5,Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2),Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2),GO:0080019; GO:0016021; GO:0006629; GO:0005778,fatty-acyl-CoA reductase (alcohol-forming) activity; integral to membrane; lipid metabolic process; peroxisomal membrane,PF07993;PF03015;,3.00E-105,CHOYP_RN45S.3.5,,,,,,,FACR1_XENLA,Xenopus laevis (African clawed frog),lipid metabolic process [GO:0006629] comp125302_c0_seq1,1725,43.3623,0.39036397,122,99,,6.00E-104,P78527,DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460),DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460),GO:0005524; GO:0002326; GO:0003677; GO:0004677; GO:0005958; GO:0033077; GO:0002360; GO:0033153; GO:0006915; GO:0007420; GO:0032869; GO:0005829; GO:0006303; GO:0035234; GO:0007507; GO:0033152; GO:0045087; GO:0005730; GO:0005654; GO:0018105; GO:0043065; GO:0045944; GO:0032481; GO:0002328; GO:0031648; GO:0010332; GO:0001756; GO:0000723; GO:0005667,ATP binding; B cell lineage commitment; DNA binding; DNA-dependent protein kinase activity; DNA-dependent protein kinase-DNA ligase 4 complex; T cell differentiation in thymus; T cell lineage commitment; T cell receptor V(D)J recombination; apoptotic process; brain development; cellular response to insulin stimulus; cytosol; double-strand break repair via nonhomologous end joining; germ cell programmed cell death; heart development; immunoglobulin V(D)J recombination; innate immune response; nucleolus; nucleoplasm; peptidyl-serine phosphorylation; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type I interferon production; pro-B cell differentiation; protein destabilization; response to gamma radiation; somitogenesis; telomere maintenance; transcription factor complex,PF02259;PF02260;PF08163;PF00454;,1.00E-37,CHOYP_LOC586799.1.1,,,,,,,PRKDC_HUMAN,Homo sapiens (Human),B cell lineage commitment [GO:0002326]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to insulin stimulus [GO:0032869]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; ectopic germ cell programmed cell death [GO:0035234]; heart development [GO:0007507]; immunoglobulin V(D)J recombination [GO:0033152]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of response to gamma radiation [GO:2001229]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of developmental growth [GO:0048639]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune system process [GO:0002684]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; pro-B cell differentiation [GO:0002328]; protein destabilization [GO:0031648]; regulation of circadian rhythm [GO:0042752]; regulation of smooth muscle cell proliferation [GO:0048660]; response to activity [GO:0014823]; response to gamma radiation [GO:0010332]; rhythmic process [GO:0048511]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]; somitogenesis [GO:0001756]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell receptor V(D)J recombination [GO:0033153]; telomere capping [GO:0016233]; thymus development [GO:0048538] comp125310_c0_seq1,251,51.3944,0.90998074,0,8,,4.00E-15,Q99N01,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0005886; GO:0042403; GO:0015349,integral to membrane; plasma membrane; thyroid hormone metabolic process; thyroid hormone transmembrane transporter activity,PF07648;PF03137;,7.00E-17,CHOYP_BRAFLDRAFT_134943.1.1,,,,,,,SO4A1_RAT,Rattus norvegicus (Rat),sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] comp125310_c1_seq1,356,49.7191,0.9579682,0,77,,1.00E-18,Q5RFF0,Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),GO:0016323; GO:0030154; GO:0016021; GO:0006811; GO:0007275; GO:0007283; GO:0005215,basolateral plasma membrane; cell differentiation; integral to membrane; ion transport; multicellular organismal development; spermatogenesis; transporter activity,PF07648;PF03137;,,,,,,,,,SO4C1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell differentiation [GO:0030154]; ion transport [GO:0006811]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp125314_c0_seq1,1206,35.4063,0.561769,1241,16755,,1.00E-66,Q7ZWJ3,Oligosaccharyltransferase complex subunit ostc,Oligosaccharyltransferase complex subunit ostc,GO:0016021,integral to membrane,PF04756;,6.00E-77,CHOYP_OSTC.1.1,7.00E-74,ruditapes_c18456,,,,,OSTC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp125319_c1_seq2,876,33.4475,0.94116397,0,73,,2.00E-28,Q9NPF2,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),GO:0000139; GO:0001537; GO:0050659; GO:0016051; GO:0005975; GO:0002063; GO:0047756; GO:0030206; GO:0048589; GO:0042733; GO:0048703; GO:0016021; GO:0043066; GO:0030512; GO:0033037; GO:0036342; GO:0009791; GO:0042127; GO:0007585,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; carbohydrate biosynthetic process; carbohydrate metabolic process; chondrocyte development; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; developmental growth; embryonic digit morphogenesis; embryonic viscerocranium morphogenesis; integral to membrane; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; polysaccharide localization; post-anal tail morphogenesis; post-embryonic development; regulation of cell proliferation; respiratory gaseous exchange,PF03567;,,,,,,,,,CHSTB_HUMAN,Homo sapiens (Human),carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585] comp125320_c0_seq1,879,37.4289,0.47261071,12,150,,2.00E-12,Q9PL03,Uncharacterized protein TC_0305,Uncharacterized protein TC_0305,GO:0004077; GO:0006464,biotin-[acetyl-CoA-carboxylase] ligase activity; cellular protein modification process,PF09825;,,,,,,,,,Y305_CHLMU,Chlamydia muridarum (strain MoPn / Nigg),cellular protein modification process [GO:0006464] comp125325_c1_seq1,966,43.0642,0.39104207,23,171,,2.00E-61,Q1LZH1,"MOSC domain-containing protein 2, mitochondrial (EC 1.-.-.-) (Mitochondrial amidoxime reducing component 2) (mARC2)",Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2),GO:0005741; GO:0030151; GO:0043546; GO:0042126; GO:0008940; GO:0005777; GO:0030170,mitochondrial outer membrane; molybdenum ion binding; molybdopterin cofactor binding; nitrate metabolic process; nitrate reductase activity; peroxisome; pyridoxal phosphate binding,PF03473;PF03476;,,,,,,,,,MOSC2_BOVIN,Bos taurus (Bovine), comp125328_c0_seq1,650,36.9231,0.33908853,29,172,,2.00E-67,A7SLC8,N-acetyltransferase 9-like protein (EC 2.3.1.-),N-acetyltransferase 9-like protein (EC 2.3.1.-),GO:0008080,N-acetyltransferase activity,PF13302;,2.00E-30,CHOYP_LOC100566602.1.1,,,,,,,NAT9_NEMVE,Nematostella vectensis (Starlet sea anemone),N-terminal protein amino acid acetylation [GO:0006474] comp125332_c0_seq1,713,37.4474,0.48915374,2053,7544,,9.00E-39,Q63362,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit),GO:0005747; GO:0016651; GO:0022904,"mitochondrial respiratory chain complex I; oxidoreductase activity, acting on NAD(P)H; respiratory electron transport chain",PF04716;,,,,,,,,,NDUA5_RAT,Rattus norvegicus (Rat),respiratory electron transport chain [GO:0022904] comp125337_c0_seq1,1182,39.8477,0.28202844,21,25,,1.00E-42,Q567G2,WD repeat-containing protein 73,WD repeat-containing protein 73,,,PF00400;,,,,,,,,,WDR73_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cerebellar Purkinje cell differentiation [GO:0021702]; cerebellum development [GO:0021549]; midbrain development [GO:0030901] comp125339_c0_seq1,847,40.2597,0.35007617,54,142,,3.00E-33,Q2LZZ7,Serine/threonine-protein kinase tricorner (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like),Serine/threonine-protein kinase tricorner (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like),GO:0005524; GO:0005737; GO:0007243; GO:0046872; GO:0005634; GO:0004674; GO:0050773,ATP binding; cytoplasm; intracellular protein kinase cascade; metal ion binding; nucleus; protein serine/threonine kinase activity; regulation of dendrite development,PF00069;,,,,,,,,,TRC_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165] comp125344_c0_seq3,299,62.2074,0.66279811,5966,7840,,,,,,,,,1.00E-85,CHOYP_LOC100931706.1.4,,,,,,,,, comp125347_c0_seq1,707,35.785,0.45009626,69,99,,7.00E-25,A6QQ14,DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4),DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4),GO:0005671; GO:0003887; GO:0008622; GO:0043966; GO:0043565,Ada2/Gcn5/Ada3 transcription activator complex; DNA-directed DNA polymerase activity; epsilon DNA polymerase complex; histone H3 acetylation; sequence-specific DNA binding,PF00808;,,,5.00E-41,ruditapes_c10955,,,,,DPOE4_BOVIN,Bos taurus (Bovine),histone H3 acetylation [GO:0043966] comp125349_c0_seq1,664,39.006,0.29623333,4,28,,,,,,,,,6.00E-17,CHOYP_LOC100696985.1.1,,,,,,,,, comp125349_c0_seq2,642,38.4735,0.2264728,0,2,,2.00E-09,Q8BGC0,HIV Tat-specific factor 1 homolog,HIV Tat-specific factor 1 homolog,GO:0003723; GO:0000166; GO:0005634; GO:0006355; GO:0006351,"RNA binding; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00076;,6.00E-17,CHOYP_LOC100696985.1.1,,,,,,,HTSF1_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125350_c0_seq1,531,38.2298,0.21626093,12,60,,3.00E-21,Q9NVH0,Exonuclease 3'-5' domain-containing protein 2 (Exonuclease 3'-5' domain-like-containing protein 2),Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;,,,,,,,,,EXD2_HUMAN,Homo sapiens (Human),DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305] comp125352_c2_seq1,533,37.3358,0.5195694,0,0,,2.00E-08,Q8BG34,UBX domain-containing protein 10 (UBX domain-containing protein 3),UBX domain-containing protein 10 (UBX domain-containing protein 3),,,PF00789;,,,,,,,,,UBX10_MOUSE,Mus musculus (Mouse), comp125354_c0_seq1,1755,40.2849,0.32354412,2236,9872,,1.00E-59,Q6P877,Proteasomal ubiquitin receptor ADRM1,Proteasomal ubiquitin receptor ADRM1,GO:0005737; GO:0061133; GO:0005634; GO:0043248; GO:0000502,cytoplasm; endopeptidase activator activity; nucleus; proteasome assembly; proteasome complex,PF04683;PF16550;,1.00E-126,CHOYP_LOC100374268.1.1,1.00E-79,ruditapes_c1836,,,,,ADRM1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),proteasome assembly [GO:0043248] comp125360_c0_seq1,1134,44.0917,0.38521242,44,47,,1.00E-53,Q6PQD5,Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),GO:0016303; GO:0005524; GO:0003677; GO:0006281; GO:0016023; GO:0071044; GO:0007094; GO:0005634; GO:0002331; GO:0047485; GO:0004674; GO:0010212; GO:0005840; GO:0003735; GO:0006412,1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA repair; cytoplasmic membrane-bounded vesicle; histone mRNA catabolic process; mitotic spindle assembly checkpoint; nucleus; pre-B cell allelic exclusion; protein N-terminus binding; protein serine/threonine kinase activity; response to ionizing radiation; ribosome; structural constituent of ribosome; translation,PF02259;PF02260;PF00454;PF11640;,,,,,,,,,ATM_PIG,Sus scrofa (Pig),DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; mitotic spindle assembly checkpoint [GO:0007094]; pre-B cell allelic exclusion [GO:0002331]; replicative senescence [GO:0090399]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; translation [GO:0006412] comp125362_c0_seq1,727,38.3769,0.67338257,40,45,,1.00E-62,Q8NBZ7,UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1),UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1),GO:0032580; GO:0033320; GO:0048040; GO:0050662; GO:0016021; GO:0005739,Golgi cisterna membrane; UDP-D-xylose biosynthetic process; UDP-glucuronate decarboxylase activity; coenzyme binding; integral to membrane; mitochondrion,PF16363;PF11803;,2.00E-36,CHOYP_UXS1.1.1,,,,,,,UXS1_HUMAN,Homo sapiens (Human),protein tetramerization [GO:0051262]; UDP-D-xylose biosynthetic process [GO:0033320] comp125366_c0_seq1,1629,35.4819,0.98098256,6,16649,female>male,1.00E-10,B1WB06,Methyltransferase-like protein 24 (EC 2.1.1.-),Methyltransferase-like protein 24 (EC 2.1.1.-),GO:0005576; GO:0008168,extracellular region; methyltransferase activity,PF13383;,,,,,,,,,MET24_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp125367_c0_seq3,1169,35.7571,0.51315827,0,0,,9.00E-34,Q8WXB4,Zinc finger protein 606 (Zinc finger protein 328),Zinc finger protein 606 (Zinc finger protein 328),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN606_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125367_c0_seq4,696,38.2184,0.43901831,0,0,,2.00E-06,Q8SW43,Zinc finger C2H2 protein ECU03_0790,Zinc finger C2H2 protein ECU03_0790,GO:0046872; GO:0003676,metal ion binding; nucleic acid binding,,,,,,,,,,Z379_ENCCU,Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite), comp125367_c0_seq5,824,36.165,0.60065614,0,0,,3.00E-19,P18741,Oocyte zinc finger protein XlCOF15 (Fragment),Oocyte zinc finger protein XlCOF15 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZO15_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125368_c0_seq1,643,42.3017,0.31776393,42,204,,6.00E-28,Q5HZY0,UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2),UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2),GO:0005789; GO:0005635; GO:0006986,endoplasmic reticulum membrane; nuclear envelope; response to unfolded protein,PF00789;,,,,,,,,,UBXN4_RAT,Rattus norvegicus (Rat),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; response to unfolded protein [GO:0006986] comp125386_c0_seq1,2451,40.1061,0.99680602,563,6593,,5.00E-33,P37801,Calponin homolog OV9M,Calponin homolog OV9M,,,PF00402;,3.00E-21,CHOYP_PHUM_PHUM289860.1.1,5.00E-86,ruditapes2_c39,,,,,CLPH_ONCVO,Onchocerca volvulus, comp125386_c0_seq2,1654,39.7219,0.99185353,156,1067,,4.00E-44,Q08093,"Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)","Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)",GO:0031032; GO:0071260; GO:0030097; GO:0030336; GO:0050765; GO:0010628; GO:0032970; GO:0042127; GO:0001725; GO:0042060,actomyosin structure organization; cellular response to mechanical stimulus; hemopoiesis; negative regulation of cell migration; negative regulation of phagocytosis; positive regulation of gene expression; regulation of actin filament-based process; regulation of cell proliferation; stress fiber; wound healing,PF00402;PF00307;,8.00E-14,CHOYP_PHUM_PHUM289860.1.1,,,,,,,CNN2_MOUSE,Mus musculus (Mouse),actomyosin structure organization [GO:0031032]; cellular response to mechanical stimulus [GO:0071260]; hemopoiesis [GO:0030097]; negative regulation of cell migration [GO:0030336]; negative regulation of phagocytosis [GO:0050765]; positive regulation of gene expression [GO:0010628]; regulation of actin filament-based process [GO:0032970]; regulation of cell proliferation [GO:0042127]; wound healing [GO:0042060] comp125389_c0_seq1,347,38.9049,0.23016064,3,0,,1.00E-11,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,2.00E-18,CHOYP_BRAFLDRAFT_128562.2.4,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp125390_c0_seq2,1357,35.9617,0.3661613,53,43,,4.00E-61,Q62559,Intraflagellar transport protein 52 homolog (Protein NGD5),Intraflagellar transport protein 52 homolog (Protein NGD5),GO:0036064; GO:0044292; GO:0009953; GO:0042733; GO:0001947; GO:0001841; GO:0032391; GO:0045862; GO:0007224,cilium basal body; dendrite terminus; dorsal/ventral pattern formation; embryonic digit morphogenesis; heart looping; neural tube formation; photoreceptor connecting cilium; positive regulation of proteolysis; smoothened signaling pathway,PF09822;,2.00E-96,CHOYP_LOC100367604.1.1,,,,,,,IFT52_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube formation [GO:0001841]; regulation of protein processing [GO:0070613]; smoothened signaling pathway [GO:0007224] comp125390_c1_seq1,440,42.7273,0.35035932,21,30,,2.00E-66,Q62559,Intraflagellar transport protein 52 homolog (Protein NGD5),Intraflagellar transport protein 52 homolog (Protein NGD5),GO:0036064; GO:0044292; GO:0009953; GO:0042733; GO:0001947; GO:0001841; GO:0032391; GO:0045862; GO:0007224,cilium basal body; dendrite terminus; dorsal/ventral pattern formation; embryonic digit morphogenesis; heart looping; neural tube formation; photoreceptor connecting cilium; positive regulation of proteolysis; smoothened signaling pathway,PF09822;,5.00E-28,CHOYP_BRAFLDRAFT_281480.1.1,,,,,,,IFT52_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube formation [GO:0001841]; regulation of protein processing [GO:0070613]; smoothened signaling pathway [GO:0007224] comp125404_c0_seq1,780,41.5385,0.69982194,7,166,,5.00E-103,Q13637,Ras-related protein Rab-32,Ras-related protein Rab-32,GO:0005525; GO:0005739; GO:0045335; GO:0030670; GO:0090382; GO:0015031; GO:0007264,GTP binding; mitochondrion; phagocytic vesicle; phagocytic vesicle membrane; phagosome maturation; protein transport; small GTPase mediated signal transduction,PF00071;,8.00E-99,CHOYP_LOC100370154.2.2,3.00E-96,ruditapes2_c2251,,,,,RAB32_HUMAN,Homo sapiens (Human),antigen processing and presentation [GO:0019882]; endosome to melanosome transport [GO:0035646]; melanosome assembly [GO:1903232]; phagosome maturation [GO:0090382]; small GTPase mediated signal transduction [GO:0007264] comp125405_c1_seq1,471,41.6136,0.49564436,25,105,,,,,,,,,2.00E-47,CHOYP_PACN2.2.2,,,,,,,,, comp125405_c2_seq1,380,47.1053,0.42970222,1,0,,3.00E-07,Q96RF0,Sorting nexin-18 (SH3 and PX domain-containing protein 3B) (Sorting nexin-associated Golgi protein 1),Sorting nexin-18 (SH3 and PX domain-containing protein 3B) (Sorting nexin-associated Golgi protein 1),GO:0007154; GO:0036089; GO:0016023; GO:0030659; GO:0006897; GO:0012505; GO:0016197; GO:0010008; GO:0031234; GO:0030426; GO:0007067; GO:0000281; GO:0043025; GO:0035091; GO:0043547; GO:0015031,cell communication; cleavage furrow formation; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle membrane; endocytosis; endomembrane system; endosomal transport; endosome membrane; extrinsic to internal side of plasma membrane; growth cone; mitosis; mitotic cytokinesis; neuronal cell body; phosphatidylinositol binding; positive regulation of GTPase activity; protein transport,PF10456;PF00787;PF14604;,,,,,,,,,SNX18_HUMAN,Homo sapiens (Human),cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of GTPase activity [GO:0043547]; vesicle organization [GO:0016050] comp125405_c3_seq1,697,42.1808,0.77057565,29,32,,1.00E-46,Q9UNF0,Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II),Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II),GO:0030036; GO:0005901; GO:0070836; GO:0072584; GO:0048858; GO:0030659; GO:0005856; GO:0005829; GO:0005769; GO:0019898; GO:0097320; GO:0045806; GO:0070300; GO:0036010; GO:0055038; GO:0032587; GO:0005215,actin cytoskeleton organization; caveola; caveola assembly; caveolin-mediated endocytosis; cell projection morphogenesis; cytoplasmic vesicle membrane; cytoskeleton; cytosol; early endosome; extrinsic to membrane; membrane tubulation; negative regulation of endocytosis; phosphatidic acid binding; protein localization to endosome; recycling endosome membrane; ruffle membrane; transporter activity,PF00611;PF00018;,1.00E-39,CHOYP_AGAP_AGAP008046.1.1,,,,,,,PACN2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; caveola assembly [GO:0070836]; caveolin-mediated endocytosis [GO:0072584]; cell projection morphogenesis [GO:0048858]; membrane tubulation [GO:0097320]; negative regulation of endocytosis [GO:0045806]; protein localization to endosome [GO:0036010]; regulation of endocytosis [GO:0030100] comp125406_c0_seq1,773,45.7956,0.69819704,23,56,,1.00E-89,F1M7Y5,Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (nPKC-iota),Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (nPKC-iota),GO:0005524; GO:0048194; GO:0043220; GO:0031252; GO:0016477; GO:0045216; GO:0034613; GO:0032869; GO:0005829; GO:0005768; GO:0035556; GO:0034351; GO:0043524; GO:0005634; GO:0005543; GO:0005886; GO:0051092; GO:2000353; GO:0090004; GO:0060252; GO:0046326; GO:0010976; GO:0043234; GO:0004697; GO:0070555; GO:0008270,ATP binding; Golgi vesicle budding; Schmidt-Lanterman incisure; cell leading edge; cell migration; cell-cell junction organization; cellular protein localization; cellular response to insulin stimulus; cytosol; endosome; intracellular signal transduction; negative regulation of glial cell apoptotic process; negative regulation of neuron apoptotic process; nucleus; phospholipid binding; plasma membrane; positive regulation of NF-kappaB transcription factor activity; positive regulation of endothelial cell apoptotic process; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glial cell proliferation; positive regulation of glucose import; positive regulation of neuron projection development; protein complex; protein kinase C activity; response to interleukin-1; zinc ion binding,PF00130;PF00564;PF00069;PF00433;,3.00E-72,CHOYP_LOC100533284.1.2,,,,,,,KPCI_RAT,Rattus norvegicus (Rat),actin filament organization [GO:0007015]; cell-cell junction organization [GO:0045216]; cell migration [GO:0016477]; cellular protein localization [GO:0034613]; cellular response to insulin stimulus [GO:0032869]; establishment of apical/basal cell polarity [GO:0035089]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein phosphorylation [GO:0006468]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434] comp125407_c0_seq1,1087,39.6504,0.5155514,40,74,,2.00E-101,Q7L5D6,Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35),Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35),GO:0071818; GO:0071816; GO:0006810,BAT3 complex; tail-anchored membrane protein insertion into ER membrane; transport,PF04190;,8.00E-50,CHOYP_LOC100741726.1.1,,,,,,,GET4_HUMAN,Homo sapiens (Human),cytoplasmic sequestering of protein [GO:0051220]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810] comp125408_c1_seq1,458,32.0961,0,120,0,,,,,,,,,,,1.00E-14,ruditapes_c4549,,,,,,, comp125412_c1_seq1,248,37.9032,0.45109429,8,21,,2.00E-39,Q960X4,Histone acetyltransferase Tip60 (EC 2.3.1.48),Histone acetyltransferase Tip60 (EC 2.3.1.48),GO:0035267; GO:0043967; GO:0004402; GO:0043486; GO:0007399; GO:0005705; GO:0048167; GO:2000331; GO:0006355; GO:0006974; GO:0006351,"NuA4 histone acetyltransferase complex; histone H4 acetylation; histone acetyltransferase activity; histone exchange; nervous system development; polytene chromosome interband; regulation of synaptic plasticity; regulation of terminal button organization; regulation of transcription, DNA-dependent; response to DNA damage stimulus; transcription, DNA-dependent",PF01853;PF11717;,9.00E-35,CHOYP_KAT5.1.1,,,,,,,TIP60_DROME,Drosophila melanogaster (Fruit fly),"cellular response to DNA damage stimulus [GO:0006974]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H4 acetylation [GO:0043967]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of gene expression [GO:0010468]; regulation of synaptic plasticity [GO:0048167]; regulation of terminal button organization [GO:2000331]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125416_c0_seq1,772,42.6166,0.86678773,67,48,,9.00E-07,Q26422,Limulus clotting factor C (FC) (EC 3.4.21.84) [Cleaved into: Limulus clotting factor C heavy chain; Limulus clotting factor C light chain; Limulus clotting factor C chain A; Limulus clotting factor C chain B],Limulus clotting factor C (FC) (EC 3.4.21.84) [Cleaved into: Limulus clotting factor C heavy chain; Limulus clotting factor C light chain; Limulus clotting factor C chain A; Limulus clotting factor C chain B],GO:0030246; GO:0007155; GO:0005576; GO:0042381; GO:0006508; GO:0004252,carbohydrate binding; cell adhesion; extracellular region; hemolymph coagulation; proteolysis; serine-type endopeptidase activity,PF03815;PF00059;PF00084;PF00089;,,,,,,,,,LFC_CARRO,Carcinoscorpius rotundicauda (Mangrove horseshoe crab) (Limulus rotundicauda),cell adhesion [GO:0007155]; hemolymph coagulation [GO:0042381] comp125418_c0_seq1,1085,43.0415,0.4781512,3,0,,5.00E-103,Q5E9G6,F-box only protein 8,F-box only protein 8,GO:0005086; GO:0030036; GO:0030054; GO:0005634; GO:0032012; GO:0000151; GO:0006511,ARF guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cell junction; nucleus; regulation of ARF protein signal transduction; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process,PF12937;PF01369;,,,,,,,,,FBX8_BOVIN,Bos taurus (Bovine),regulation of ARF protein signal transduction [GO:0032012]; ubiquitin-dependent protein catabolic process [GO:0006511] comp125418_c0_seq3,781,41.4853,0.50750226,0,0,,1.00E-21,Q99418,"Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)","Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)",GO:0005086; GO:0030036; GO:0005737; GO:0006897; GO:0005543; GO:0005886; GO:0032012; GO:0030155,ARF guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cytoplasm; endocytosis; phospholipid binding; plasma membrane; regulation of ARF protein signal transduction; regulation of cell adhesion,PF00169;PF01369;,5.00E-44,CHOYP_FBXO8.1.1,,,,,,,CYH2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012] comp125424_c0_seq2,1233,40.4704,0.43126776,5,3,,3.00E-06,Q9QYM8,Centromere protein H (CENP-H),Centromere protein H (CENP-H),GO:0007059; GO:0000777; GO:0000776; GO:0051382; GO:0043515; GO:0051383; GO:0007067; GO:0005634,chromosome segregation; condensed chromosome kinetochore; kinetochore; kinetochore assembly; kinetochore binding; kinetochore organization; mitosis; nucleus,PF05837;,,,,,,,,,CENPH_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; kinetochore organization [GO:0051383]; mitotic nuclear division [GO:0007067] comp125428_c0_seq1,1545,41.7476,0.47676523,80,162,,1.00E-130,O14678,ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69),ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69),GO:0005524; GO:0006200; GO:0043190; GO:0042626; GO:0009235; GO:0005789; GO:0016021; GO:0005778; GO:0005777,"ATP binding; ATP catabolic process; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cobalamin metabolic process; endoplasmic reticulum membrane; integral to membrane; peroxisomal membrane; peroxisome",PF06472;PF00005;,8.00E-39,CHOYP_ABCD4.1.2,,,,,,,ABCD4_HUMAN,Homo sapiens (Human),cobalamin metabolic process [GO:0009235]; transmembrane transport [GO:0055085] comp125431_c0_seq1,1060,39.6226,0.44335632,38,201,,4.00E-20,D3Z5L6,MFS-type transporter SLC18B1 (Solute carrier family 18 member B1),MFS-type transporter SLC18B1 (Solute carrier family 18 member B1),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S18B1_MOUSE,Mus musculus (Mouse), comp125433_c0_seq2,297,40.7407,0.40710844,0,0,,1.00E-12,Q0CLX3,Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1),Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1),GO:0005524; GO:0006914; GO:0034045; GO:0004674; GO:0015031,ATP binding; autophagy; pre-autophagosomal structure membrane; protein serine/threonine kinase activity; protein transport,PF12063;PF00069;,,,,,,,,,ATG1_ASPTN,Aspergillus terreus (strain NIH 2624 / FGSC A1156),autophagosome assembly [GO:0000045]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein autophosphorylation [GO:0046777]; protein transport [GO:0015031] comp125433_c1_seq1,499,40.6814,0.24338104,0,0,,5.00E-15,Q6VZ17,Hormonally up-regulated neu tumor-associated kinase homolog B (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V B) (xMAK-V B) (Fragment),Hormonally up-regulated neu tumor-associated kinase homolog B (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V B) (xMAK-V B) (Fragment),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,HUNKB_XENLA,Xenopus laevis (African clawed frog), comp125433_c1_seq3,756,42.1958,0.6007947,0,0,,1.00E-89,Q6BLJ9,Serine/threonine-protein kinase CBK1 (EC 2.7.11.1),Serine/threonine-protein kinase CBK1 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,CBK1_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),budding cell apical bud growth [GO:0007118]; cell separation after cytokinesis [GO:0000920]; cellular response to osmotic stress [GO:0071470]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; establishment or maintenance of bipolar cell polarity regulating cell shape [GO:0061246]; fungal-type cell wall assembly [GO:0071940]; maintenance of protein location in cell cortex of cell tip [GO:0097248]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of bipolar cell growth [GO:0051518]; regulation of establishment or maintenance of bipolar cell polarity regulating cell shape [GO:2000100]; regulation of fungal-type cell wall organization [GO:0060237] comp125433_c1_seq4,838,42.4821,0.56183116,0,0,,1.00E-143,Q5R8M1,Serine/threonine-protein kinase 38 (EC 2.7.11.1),Serine/threonine-protein kinase 38 (EC 2.7.11.1),GO:0005524; GO:0070688; GO:0005737; GO:0007243; GO:0000287; GO:0043407; GO:0005886; GO:0004674,ATP binding; MLL5-L complex; cytoplasm; intracellular protein kinase cascade; magnesium ion binding; negative regulation of MAP kinase activity; plasma membrane; protein serine/threonine kinase activity,PF00069;PF00433;,2.00E-144,CHOYP_ISCW_ISCW017707.1.1,,,,,,,STK38_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intracellular signal transduction [GO:0035556]; negative regulation of MAP kinase activity [GO:0043407] comp125438_c0_seq1,1287,35.1981,0.50856858,66,109,,1.00E-88,P52486,Ubiquitin-conjugating enzyme E2-22 kDa (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Ubiquitin-conjugating enzyme E2-22 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0051726; GO:0004842,ATP binding; regulation of cell cycle; ubiquitin-protein ligase activity,PF00627;PF00179;,1.00E-91,CHOYP_LOC726145.1.1,,,,,,,UBCD4_DROME,Drosophila melanogaster (Fruit fly),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cell cycle [GO:0051726] comp125443_c0_seq1,1248,44.391,0.58662142,24,221,,2.00E-151,P32865,G protein-coupled receptor kinase 1 (EC 2.7.11.16),G protein-coupled receptor kinase 1 (EC 2.7.11.16),GO:0005524; GO:0004703; GO:0007474; GO:0016060; GO:0035091; GO:0007603; GO:0050254; GO:0038032,"ATP binding; G-protein coupled receptor kinase activity; imaginal disc-derived wing vein specification; metarhodopsin inactivation; phosphatidylinositol binding; phototransduction, visible light; rhodopsin kinase activity; termination of G-protein coupled receptor signaling pathway",PF00169;PF00069;PF00615;,3.00E-169,CHOYP_SMP_159010.1.1.1,,,,,,,GPRK1_DROME,Drosophila melanogaster (Fruit fly),"G-protein coupled receptor signaling pathway [GO:0007186]; imaginal disc-derived wing vein specification [GO:0007474]; metarhodopsin inactivation [GO:0016060]; phototransduction, visible light [GO:0007603]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]" comp125443_c3_seq1,338,43.787,0.69636464,4,14,,3.00E-26,Q8MYF1,Probable serine/threonine-protein kinase DDB_G0277449 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0277449 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,Y2070_DICDI,Dictyostelium discoideum (Slime mold),intracellular signal transduction [GO:0035556] comp125453_c0_seq1,990,44.3434,0.66720034,67,49,,7.00E-71,Q96DR7,Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor),Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor),GO:0005089; GO:0005543; GO:0035023; GO:0001726,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction; ruffle,PF00621;PF14604;,1.00E-65,CHOYP_ISCW_ISCW001487.2.2,,,,,,,ARHGQ_HUMAN,Homo sapiens (Human),endothelial cell morphogenesis [GO:0001886]; regulation of Rho protein signal transduction [GO:0035023]; ruffle assembly [GO:0097178] comp125453_c1_seq1,278,39.9281,1.19942028,7,6,,,,,,,,,,,3.00E-14,ruditapes_c8722,,,,,,, comp125455_c0_seq2,233,40.3433,0.10670511,7,7,,5.00E-23,P47758,Signal recognition particle receptor subunit beta (SR-beta),Signal recognition particle receptor subunit beta (SR-beta),GO:0005525; GO:0005881; GO:0005789; GO:0016021; GO:0016020; GO:0007264,GTP binding; cytoplasmic microtubule; endoplasmic reticulum membrane; integral to membrane; membrane; small GTPase mediated signal transduction,PF09439;,,,,,,,,,SRPRB_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp125459_c1_seq1,906,37.7483,0.84163418,56,113,,3.00E-34,P17081,Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A),Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A),GO:0005525; GO:0003924; GO:0005884; GO:0030866; GO:0005829; GO:0008286; GO:0045121; GO:0090005; GO:0005886; GO:0051491; GO:0046326; GO:0045944; GO:0032956; GO:0008360; GO:0051056; GO:0007264,GTP binding; GTPase activity; actin filament; cortical actin cytoskeleton organization; cytosol; insulin receptor signaling pathway; membrane raft; negative regulation of establishment of protein localization to plasma membrane; plasma membrane; positive regulation of filopodium assembly; positive regulation of glucose import; positive regulation of transcription from RNA polymerase II promoter; regulation of actin cytoskeleton organization; regulation of cell shape; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RHOQ_HUMAN,Homo sapiens (Human),cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] comp125460_c0_seq2,2111,47.7973,0.71364263,83,67,,2.00E-99,Q8NEA6,Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515),Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515),GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0045944; GO:0003700; GO:0006366,DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,,2.00E-123,CHOYP_LOC100074304.1.1,,,,,,,GLIS3_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp125461_c0_seq1,1854,34.7357,0.62736761,6,87,,4.00E-15,Q8R1V4,Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (p24 family protein alpha-3) (p24alpha3) (p26),Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (p24 family protein alpha-3) (p24alpha3) (p26),GO:0005789; GO:0016021; GO:0043123; GO:0015031; GO:0004871,endoplasmic reticulum membrane; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein transport; signal transducer activity,PF01105;,,,,,,,,,TMED4_MOUSE,Mus musculus (Mouse),positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein transport [GO:0015031] comp125461_c0_seq3,1574,34.6887,0.57095888,0,5,,6.00E-72,D3ZTX0,Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27),Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27),GO:0030663; GO:0012507; GO:0005794; GO:0005783; GO:0005789; GO:0005793; GO:0033116; GO:0016021; GO:0015031,COPI-coated vesicle membrane; ER to Golgi transport vesicle membrane; Golgi apparatus; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; protein transport,PF01105;,1.00E-42,CHOYP_TMED7.1.3,,,,,,,TMED7_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp125468_c0_seq3,1847,37.8993,0.98482455,191,10,,2.00E-61,Q66H10,F-box only protein 39,F-box only protein 39,,,PF12937;,,,,,,,,,FBX39_RAT,Rattus norvegicus (Rat),SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp125470_c0_seq1,1202,39.4343,0.6787461,55,80,,7.00E-81,Q9BW91,"ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)","ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)",GO:0046032; GO:0047631; GO:0019144; GO:0046709; GO:0043262; GO:0005759; GO:0034656,ADP catabolic process; ADP-ribose diphosphatase activity; ADP-sugar diphosphatase activity; IDP catabolic process; adenosine-diphosphatase activity; mitochondrial matrix; nucleobase-containing small molecule catabolic process,PF00293;,5.00E-34,CHOYP_LOC756760.1.1,,,,,,,NUDT9_HUMAN,Homo sapiens (Human),ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709]; nucleobase-containing small molecule catabolic process [GO:0034656] comp125472_c1_seq2,346,28.9017,0.56081277,16,34,,,,,,,,,,,3.00E-15,ruditapes_lrc23864,,,,,,, comp125475_c0_seq1,312,32.3718,0.49214342,4,26,,3.00E-08,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp125475_c0_seq2,242,33.8843,0.57823712,10,20,,6.00E-08,P92555,Uncharacterized mitochondrial protein AtMg01250 (ORF102),Uncharacterized mitochondrial protein AtMg01250 (ORF102),GO:0003723; GO:0006278; GO:0003964; GO:0005739,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; mitochondrion,PF00078;,1.00E-13,CHOYP_LOC100555596.2.2,,,,,,,M1250_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp125476_c0_seq1,762,42.5197,1.04919967,15,95,,3.00E-06,Q9ES30,Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),GO:0005581; GO:0005615; GO:0042593; GO:0042802; GO:0045721; GO:0070374; GO:0070165; GO:0050715; GO:0051897; GO:0051259,collagen; extracellular space; glucose homeostasis; identical protein binding; negative regulation of gluconeogenesis; positive regulation of ERK1 and ERK2 cascade; positive regulation of adiponectin secretion; positive regulation of cytokine secretion; positive regulation of protein kinase B signaling cascade; protein oligomerization,PF00386;PF01391;,,,,,,,,,C1QT3_MOUSE,Mus musculus (Mouse),cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206] comp125478_c0_seq1,246,49.187,0.75725889,8,12,,1.00E-11,Q13591,Semaphorin-5A (Semaphorin-F) (Sema F),Semaphorin-5A (Semaphorin-F) (Sema F),GO:0007411; GO:0008046; GO:0007155; GO:0007267; GO:0016021; GO:0001569; GO:0005886,axon guidance; axon guidance receptor activity; cell adhesion; cell-cell signaling; integral to membrane; patterning of blood vessels; plasma membrane,PF01403;PF00090;,,,,,,,,,SEM5A_HUMAN,Homo sapiens (Human),axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] comp125487_c0_seq10,1637,36.5302,0.44514918,0,0,,4.00E-25,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125487_c0_seq12,1509,36.3817,0.46492658,0,0,,8.00E-24,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125492_c0_seq1,1569,34.0982,0.39533338,907,3896,,1.00E-29,Q9CQV1,Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16),Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16),GO:0005744; GO:0030150,mitochondrial inner membrane presequence translocase complex; protein import into mitochondrial matrix,,6.00E-34,CHOYP_SMP_168770.1.1,,,,,,,TIM16_MOUSE,Mus musculus (Mouse),DNA biosynthetic process [GO:0071897]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of ATPase activity [GO:0032780]; ossification [GO:0001503]; protein import into mitochondrial matrix [GO:0030150] comp125501_c0_seq1,2598,41.0701,0.51736845,104,316,,2.00E-31,Q7T308,E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168),E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168),GO:0070530; GO:0003682; GO:0006302; GO:0070535; GO:0035518; GO:0036351; GO:0036352; GO:0042393; GO:0045190; GO:0045900; GO:0005634; GO:0045739; GO:0010212; GO:0035861; GO:0000151; GO:0006511; GO:0004842; GO:0008270,K63-linked polyubiquitin binding; chromatin binding; double-strand break repair; histone H2A K63-linked ubiquitination; histone H2A monoubiquitination; histone H2A-K13 ubiquitination; histone H2A-K15 ubiquitination; histone binding; isotype switching; negative regulation of translational elongation; nucleus; positive regulation of DNA repair; response to ionizing radiation; site of double-strand break; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN168_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone H2A-K13 ubiquitination [GO:0036351]; histone H2A-K15 ubiquitination [GO:0036352]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A monoubiquitination [GO:0035518]; isotype switching [GO:0045190]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; ubiquitin-dependent protein catabolic process [GO:0006511] comp125505_c0_seq1,1029,38.5811,0.4199158,31,140,,1.00E-40,Q9ULK4,Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130),Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130),GO:0016592; GO:0005654; GO:0006357; GO:0003713; GO:0005667; GO:0006367,mediator complex; nucleoplasm; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor complex; transcription initiation from RNA polymerase II promoter,PF11573;,,,,,,,,,MED23_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp125505_c1_seq1,1064,44.3609,0.34424582,29,102,,5.00E-142,Q6P423,Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23),Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11573;,4.00E-72,CHOYP_MED23.1.1,,,,,,,MED23_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125507_c0_seq1,1151,44.9175,0.53856983,7,4,,4.00E-103,Q10471,Polypeptide N-acetylgalactosaminyltransferase 2 (EC 2.4.1.41) (Polypeptide GalNAc transferase 2) (GalNAc-T2) (pp-GaNTase 2) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form],Polypeptide N-acetylgalactosaminyltransferase 2 (EC 2.4.1.41) (Polypeptide GalNAc transferase 2) (GalNAc-T2) (pp-GaNTase 2) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form],GO:0032580; GO:0005795; GO:0016266; GO:0005576; GO:0002378; GO:0030173; GO:0030145; GO:0048471; GO:0004653; GO:0043687; GO:0018242; GO:0018243,Golgi cisterna membrane; Golgi stack; O-glycan processing; extracellular region; immunoglobulin biosynthetic process; integral to Golgi membrane; manganese ion binding; perinuclear region of cytoplasm; polypeptide N-acetylgalactosaminyltransferase activity; post-translational protein modification; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine,PF00535;PF00652;,6.00E-178,CHOYP_GALT2.1.1,,,,,,,GALT2_HUMAN,Homo sapiens (Human),immunoglobulin biosynthetic process [GO:0002378]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] comp125507_c0_seq2,1174,44.8041,0.5480332,2,0,,4.00E-71,Q9JJ61,Polypeptide N-acetylgalactosaminyltransferase 16 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1) (Polypeptide N-acetylgalactosaminyltransferase-like protein 1) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1),Polypeptide N-acetylgalactosaminyltransferase 16 (EC 2.4.1.41) (Polypeptide GalNAc transferase 16) (GalNAc-T16) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1) (Polypeptide N-acetylgalactosaminyltransferase-like protein 1) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1),GO:0000139; GO:0016021; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,1.00E-15,CHOYP_BRAFLDRAFT_246892.1.1,,,,,,,GLTL1_MOUSE,Mus musculus (Mouse),protein glycosylation [GO:0006486] comp125519_c0_seq1,1440,40.5556,0.37307461,57,158,,9.00E-139,Q6PB03,Phospholipase D3 (PLD 3) (EC 3.1.4.4) (Choline phosphatase 3) (Phosphatidylcholine-hydrolyzing phospholipase D3),Phospholipase D3 (PLD 3) (EC 3.1.4.4) (Choline phosphatase 3) (Phosphatidylcholine-hydrolyzing phospholipase D3),GO:0070290; GO:0005789; GO:0016021; GO:0016042; GO:0004630,NAPE-specific phospholipase D activity; endoplasmic reticulum membrane; integral to membrane; lipid catabolic process; phospholipase D activity,PF00614;PF13918;,3.00E-44,CHOYP_LOC659617.1.1,,,,,,,PLD3_XENLA,Xenopus laevis (African clawed frog),lipid catabolic process [GO:0016042] comp125530_c0_seq1,544,43.3824,0.48358637,1,14,,2.00E-65,Q9CWK8,Sorting nexin-2,Sorting nexin-2,GO:0007154; GO:0031901; GO:0010008; GO:0006886; GO:0035091; GO:0008565,cell communication; early endosome membrane; endosome membrane; intracellular protein transport; phosphatidylinositol binding; protein transporter activity,PF00787;PF03700;PF09325;,1.00E-62,CHOYP_SNX2.1.1,,,,,,,SNX2_MOUSE,Mus musculus (Mouse),"early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; protein oligomerization [GO:0051259]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle organization [GO:0016050]" comp125530_c0_seq2,489,43.7628,0.44513268,6,12,,1.00E-09,Q8CE50,Sorting nexin-30,Sorting nexin-30,GO:0007154; GO:0005737; GO:0035091; GO:0015031,cell communication; cytoplasm; phosphatidylinositol binding; protein transport,PF03114;PF00787;,,,,,,,,,SNX30_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle organization [GO:0016050] comp125536_c0_seq1,569,44.1125,0.4439266,16,0,,2.00E-18,Q9HCE0,Ectopic P granules protein 5 homolog,Ectopic P granules protein 5 homolog,GO:0006914,autophagy,,,,,,,,,,EPG5_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; endocytic recycling [GO:0032456] comp125537_c0_seq1,519,48.3622,0.37215493,25,39,,1.00E-15,Q0VGY8,"Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)","Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)",GO:0043679; GO:0030054; GO:0030425; GO:0097062; GO:0007520; GO:0043025; GO:0014069; GO:0045211; GO:0008542,axon terminus; cell junction; dendrite; dendritic spine maintenance; myoblast fusion; neuronal cell body; postsynaptic density; postsynaptic membrane; visual learning,PF00023;PF12796;,4.00E-49,CHOYP_LOC100368376.2.2,,,,,,,TANC1_MOUSE,Mus musculus (Mouse),dendritic spine maintenance [GO:0097062]; myoblast fusion [GO:0007520]; visual learning [GO:0008542] comp125537_c1_seq1,1466,40.6548,0.584509,0,10,,2.00E-42,Q3EC11,Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255),Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255),GO:0005794; GO:0000139; GO:0016021; GO:0016746; GO:0008270,"Golgi apparatus; Golgi membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,2.00E-123,CHOYP_LOC100368376.2.2,,,,,,,ZDHC2_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp125537_c1_seq2,595,42.3529,0.5660035,0,4,,3.00E-13,Q554E7,Putative ZDHHC-type palmitoyltransferase 5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5),Putative ZDHHC-type palmitoyltransferase 5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,,,,,,,,,ZDHC5_DICDI,Dictyostelium discoideum (Slime mold), comp125537_c1_seq3,912,39.2544,0.58123319,0,0,,7.00E-25,Q3EC11,Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255),Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255),GO:0005794; GO:0000139; GO:0016021; GO:0016746; GO:0008270,"Golgi apparatus; Golgi membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,,,,,,,,,ZDHC2_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp125539_c0_seq1,1200,35.1667,0.37851493,3402,294,,2.00E-102,P56597,Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5),Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0003351; GO:0043066; GO:0004550; GO:0009116; GO:0036126; GO:0007286; GO:0021591,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; epithelial cilium movement; negative regulation of apoptotic process; nucleoside diphosphate kinase activity; nucleoside metabolic process; sperm flagellum; spermatid development; ventricular system development,PF05186;PF00334;,8.00E-120,CHOYP_BRAFLDRAFT_61845.1.1,4.00E-115,ruditapes_c25759,5.00E-120,DV736572.p.cg.6,5,,NDK5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591] comp125542_c0_seq2,2263,43.703,0.34589441,123,77,,0,Q92538,Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),GO:0005086; GO:0048205; GO:0000139; GO:0005795; GO:0005801; GO:0005788; GO:0005739; GO:0019048; GO:0005777; GO:0006892; GO:0032012; GO:0006890; GO:0005802,"ARF guanyl-nucleotide exchange factor activity; COPI coating of Golgi vesicle; Golgi membrane; Golgi stack; cis-Golgi network; endoplasmic reticulum lumen; mitochondrion; modulation by virus of host morphology or physiology; peroxisome; post-Golgi vesicle-mediated transport; regulation of ARF protein signal transduction; retrograde vesicle-mediated transport, Golgi to ER; trans-Golgi network",PF01369;PF12783;,4.00E-102,CHOYP_LOC579332.1.1,,,,,,,GBF1_HUMAN,Homo sapiens (Human),"cell activation involved in immune response [GO:0002263]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]" comp125542_c0_seq3,713,38.9902,0.33552698,0,11,,1.00E-17,Q6P1I6,PH and SEC7 domain-containing protein 2 (Pleckstrin homology and SEC7 domain-containing protein 2),PH and SEC7 domain-containing protein 2 (Pleckstrin homology and SEC7 domain-containing protein 2),GO:0005086; GO:0030054; GO:0030425; GO:0016021; GO:0030182; GO:0043025; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell junction; dendrite; integral to membrane; neuron differentiation; neuronal cell body; phospholipid binding; regulation of ARF protein signal transduction,PF01369;,2.00E-99,CHOYP_LOC579332.1.1,,,,,,,PSD2_MOUSE,Mus musculus (Mouse),regulation of ARF protein signal transduction [GO:0032012] comp125550_c0_seq2,471,42.6752,1.08908998,0,16,,3.00E-18,P20420,Neuronal acetylcholine receptor subunit alpha-5,Neuronal acetylcholine receptor subunit alpha-5,GO:0042166; GO:0004889; GO:0030054; GO:0030425; GO:0016021; GO:0043025; GO:0005886; GO:0045211,acetylcholine binding; acetylcholine-activated cation-selective channel activity; cell junction; dendrite; integral to membrane; neuronal cell body; plasma membrane; postsynaptic membrane,PF02931;PF02932;,,,,,,,,,ACHA5_RAT,Rattus norvegicus (Rat),"neuromuscular synaptic transmission [GO:0007274]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" comp125553_c1_seq3,1603,38.3656,0.48513673,26,34,,1.00E-38,P97393,Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),GO:0005525; GO:0005096; GO:0005737; GO:0016020; GO:0043547; GO:0030335; GO:0002053; GO:0008361; GO:0007264,GTP binding; GTPase activator activity; cytoplasm; membrane; positive regulation of GTPase activity; positive regulation of cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; small GTPase mediated signal transduction,PF01846;PF00071;PF00620;PF16512;,,,,,,,,,RHG05_MOUSE,Mus musculus (Mouse),positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264] comp125555_c0_seq1,1087,40.2024,0.67490966,336,535,,2.00E-48,O43543,DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2),DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2),GO:0005524; GO:0003677; GO:0006281; GO:0008094; GO:0000724; GO:0001701; GO:0007126; GO:0043524; GO:0005634; GO:0050769; GO:0010165; GO:0010332,ATP binding; DNA binding; DNA repair; DNA-dependent ATPase activity; double-strand break repair via homologous recombination; in utero embryonic development; meiosis; negative regulation of neuron apoptotic process; nucleus; positive regulation of neurogenesis; response to X-ray; response to gamma radiation,PF08423;,,,,,,,,,XRCC2_HUMAN,Homo sapiens (Human),centrosome organization [GO:0051297]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via homologous recombination [GO:0000724]; in utero embryonic development [GO:0001701]; meiotic DNA recombinase assembly [GO:0000707]; meiotic nuclear division [GO:0007126]; mitotic cell cycle [GO:0000278]; mitotic recombination [GO:0006312]; multicellular organism growth [GO:0035264]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of neurogenesis [GO:0050769]; reciprocal meiotic recombination [GO:0007131]; regulation of fibroblast apoptotic process [GO:2000269]; response to gamma radiation [GO:0010332]; response to ionizing radiation [GO:0010212]; response to X-ray [GO:0010165]; somitogenesis [GO:0001756]; strand displacement [GO:0000732]; strand invasion [GO:0042148] comp125560_c0_seq1,775,37.2903,0.45186411,17,83,,8.00E-21,P49961,Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39),Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39),GO:0005524; GO:0006200; GO:0007186; GO:0005605; GO:0007596; GO:0007155; GO:0005887; GO:0017110; GO:0017111; GO:0030168; GO:0009181,ATP binding; ATP catabolic process; G-protein coupled receptor signaling pathway; basal lamina; blood coagulation; cell adhesion; integral to plasma membrane; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; platelet activation; purine ribonucleoside diphosphate catabolic process,PF01150;,,,,,,,,,ENTP1_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; cell adhesion [GO:0007155] comp125563_c0_seq3,1199,42.1184,0.53955139,8,4,,1.00E-37,Q9BWF2,TRAF-interacting protein (RING finger protein 206),E3 ubiquitin-protein ligase TRAIP (EC 6.3.2.-) (RING finger protein 206) (TRAF-interacting protein),GO:0006915; GO:0008283; GO:0005737; GO:0048471; GO:0005886; GO:0005057; GO:0007165; GO:0008270,apoptotic process; cell proliferation; cytoplasm; perinuclear region of cytoplasm; plasma membrane; receptor signaling protein activity; signal transduction; zinc ion binding,PF13639;,,,,,,,,,TRAIP_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; intracellular signal transduction [GO:0035556]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; signal transduction [GO:0007165] comp125563_c0_seq4,801,44.5693,0.46579835,4,0,,8.00E-07,Q95SP2,E3 ubiquitin-protein ligase HRD1 (EC 6.3.2.-) (Septin-interacting protein 3) (Synoviolin),E3 ubiquitin-protein ligase HRD1 (EC 6.3.2.-) (Septin-interacting protein 3) (Synoviolin),GO:0030433; GO:0005783; GO:0005789; GO:0030968; GO:0016021; GO:0004842; GO:0008270,ER-associated protein catabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum unfolded protein response; integral to membrane; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,HRD1_DROME,Drosophila melanogaster (Fruit fly),endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp125584_c0_seq1,918,37.6906,0.74180292,9709,26429,,4.00E-30,P55954,"Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)","Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)",GO:0004129; GO:0046872; GO:0006123; GO:0005743,"cytochrome-c oxidase activity; metal ion binding; mitochondrial electron transport, cytochrome c to oxygen; mitochondrial inner membrane",PF02284;,,,8.00E-15,ruditapes2_lrc3516,,,,,COX5A_CAEEL,Caenorhabditis elegans,"mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]" comp125595_c0_seq1,860,43.6047,1.00412583,0,256,,1.00E-45,P28714,Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5),Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5),GO:0005576; GO:0004602; GO:0006979,extracellular region; glutathione peroxidase activity; response to oxidative stress,PF00255;,,,2.00E-111,ruditapes_c1355,,,,,GPX5_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),response to oxidative stress [GO:0006979] comp125596_c0_seq6,440,37.9545,0.45290727,1,0,,7.00E-06,Q24742,Histone-lysine N-methyltransferase trithorax (EC 2.1.1.43),Histone-lysine N-methyltransferase trithorax (EC 2.1.1.43),GO:0042800; GO:0035097; GO:0007275; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; multicellular organismal development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,,,,,,,,,TRX_DROVI,Drosophila virilis (Fruit fly),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp125596_c0_seq8,594,38.8889,0.47080368,0,0,,2.00E-20,Q2YDW7,N-lysine methyltransferase SETD8 (EC 2.1.1.-) (H4-K20-HMTase SETD8) (Histone-lysine N-methyltransferase SETD8) (EC 2.1.1.43) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8),N-lysine methyltransferase KMT5A (EC 2.1.1.-) (H4-K20-HMTase KMT5A) (Histone-lysine N-methyltransferase KMT5A) (EC 2.1.1.43) (Lysine-specific methylase 5A) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8),GO:0051301; GO:0005694; GO:0018024; GO:0007067; GO:0000122; GO:0005634; GO:0002039; GO:0018026; GO:0043516; GO:0006351,"cell division; chromosome; histone-lysine N-methyltransferase activity; mitosis; negative regulation of transcription from RNA polymerase II promoter; nucleus; p53 binding; peptidyl-lysine monomethylation; regulation of DNA damage response, signal transduction by p53 class mediator; transcription, DNA-dependent",PF00856;,,,,,,,,,SETD8_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-lysine monomethylation [GO:0018026]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; transcription, DNA-templated [GO:0006351]" comp125604_c0_seq1,1511,38.7823,0.66280463,126,89,,2.00E-107,Q3TSG4,RNA demethylase ALKBH5 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5),RNA demethylase ALKBH5 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5),GO:0030154; GO:0006406; GO:0006397; GO:0046872; GO:0016607; GO:0035515; GO:0035553; GO:0016706; GO:0001666; GO:0007283,"cell differentiation; mRNA export from nucleus; mRNA processing; metal ion binding; nuclear speck; oxidative RNA demethylase activity; oxidative single-stranded RNA demethylation; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; response to hypoxia; spermatogenesis",PF13532;,4.00E-99,CHOYP_BRAFLDRAFT_126925.1.1,,,,,,,ALKB5_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; oxidative single-stranded RNA demethylation [GO:0035553]; positive regulation of defense response to virus by host [GO:0002230]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283]; xenophagy [GO:0098792] comp125608_c0_seq10,328,39.939,0.85193824,12,30,,,,,,,,,,,1.00E-19,ruditapes_c29520,,,,,,, comp125614_c0_seq1,342,38.5965,0.39407506,69,0,,,,,,,,,,,4.00E-13,ruditapes2_c1288,,,,,,, comp125620_c1_seq1,627,38.437,0.77958819,12,62,,9.00E-12,Q5RBQ0,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12,GO:0007186; GO:0005834; GO:0004871,G-protein coupled receptor signaling pathway; heterotrimeric G-protein complex; signal transducer activity,PF00631;,1.00E-13,CHOYP_TYW2.1.1,8.00E-45,ruditapes_c15409,,,,,GBG12_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),G-protein coupled receptor signaling pathway [GO:0007186] comp125622_c0_seq1,485,45.1546,0.69565513,26,15,,6.00E-65,Q0IHU9,Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1),Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1),GO:0006915; GO:0005737,apoptotic process; cytoplasm,PF12496;PF13716;,4.00E-75,CHOYP_PRUN2.1.1,3.00E-93,ruditapes_c10113,,,,,PRUN2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),apoptotic process [GO:0006915] comp125624_c1_seq2,961,42.1436,0.52809719,12,2,,1.00E-09,Q8C0Y0,Serine/threonine-protein phosphatase 4 regulatory subunit 4,Serine/threonine-protein phosphatase 4 regulatory subunit 4,GO:0005737; GO:0008287,cytoplasm; protein serine/threonine phosphatase complex,,,,,,,,,,PP4R4_MOUSE,Mus musculus (Mouse),negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163] comp125625_c3_seq1,935,43.8503,0.71441942,6,25,,2.00E-44,P98078,Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein),Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein),GO:0035612; GO:0016055; GO:0007257; GO:0016324; GO:0006915; GO:0038024; GO:0000904; GO:0071560; GO:0035615; GO:0048268; GO:0030132; GO:0030665; GO:0005737; GO:0007492; GO:0007588; GO:0001701; GO:0005178; GO:0030099; GO:0060766; GO:0043066; GO:0090090; GO:2001237; GO:0032091; GO:0045892; GO:0005634; GO:0005546; GO:0006907; GO:0060391; GO:2000096; GO:0030335; GO:2000370; GO:2000643; GO:0010718; GO:2001046; GO:0010862; GO:0032436; GO:0001921; GO:1900026; GO:0032968; GO:0045893; GO:0030511; GO:0015031; GO:0070022,"AP-2 adaptor complex binding; Wnt receptor signaling pathway; activation of JUN kinase activity; apical plasma membrane; apoptotic process; cargo receptor activity; cell morphogenesis involved in differentiation; cellular response to transforming growth factor beta stimulus; clathrin adaptor activity; clathrin coat assembly; clathrin coat of coated pit; clathrin-coated vesicle membrane; cytoplasm; endoderm development; excretion; in utero embryonic development; integrin binding; myeloid cell differentiation; negative regulation of androgen receptor signaling pathway; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of protein binding; negative regulation of transcription, DNA-dependent; nucleus; phosphatidylinositol-4,5-bisphosphate binding; pinocytosis; positive regulation of SMAD protein import into nucleus; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; positive regulation of cell migration; positive regulation of clathrin-mediated endocytosis; positive regulation of early endosome to late endosome transport; positive regulation of epithelial to mesenchymal transition; positive regulation of integrin-mediated signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of receptor recycling; positive regulation of substrate adhesion-dependent cell spreading; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transforming growth factor beta receptor signaling pathway; protein transport; transforming growth factor beta receptor homodimeric complex",PF00640;,,,,,,,,,DAB2_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; Wnt signaling pathway [GO:0016055]" comp125625_c3_seq2,947,43.8226,0.70673828,4,1,,2.00E-44,P98078,Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein),Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein),GO:0035612; GO:0016055; GO:0007257; GO:0016324; GO:0006915; GO:0038024; GO:0000904; GO:0071560; GO:0035615; GO:0048268; GO:0030132; GO:0030665; GO:0005737; GO:0007492; GO:0007588; GO:0001701; GO:0005178; GO:0030099; GO:0060766; GO:0043066; GO:0090090; GO:2001237; GO:0032091; GO:0045892; GO:0005634; GO:0005546; GO:0006907; GO:0060391; GO:2000096; GO:0030335; GO:2000370; GO:2000643; GO:0010718; GO:2001046; GO:0010862; GO:0032436; GO:0001921; GO:1900026; GO:0032968; GO:0045893; GO:0030511; GO:0015031; GO:0070022,"AP-2 adaptor complex binding; Wnt receptor signaling pathway; activation of JUN kinase activity; apical plasma membrane; apoptotic process; cargo receptor activity; cell morphogenesis involved in differentiation; cellular response to transforming growth factor beta stimulus; clathrin adaptor activity; clathrin coat assembly; clathrin coat of coated pit; clathrin-coated vesicle membrane; cytoplasm; endoderm development; excretion; in utero embryonic development; integrin binding; myeloid cell differentiation; negative regulation of androgen receptor signaling pathway; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of protein binding; negative regulation of transcription, DNA-dependent; nucleus; phosphatidylinositol-4,5-bisphosphate binding; pinocytosis; positive regulation of SMAD protein import into nucleus; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; positive regulation of cell migration; positive regulation of clathrin-mediated endocytosis; positive regulation of early endosome to late endosome transport; positive regulation of epithelial to mesenchymal transition; positive regulation of integrin-mediated signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of receptor recycling; positive regulation of substrate adhesion-dependent cell spreading; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transforming growth factor beta receptor signaling pathway; protein transport; transforming growth factor beta receptor homodimeric complex",PF00640;,2.00E-30,CHOYP_DAB2.1.1,,,,,,,DAB2_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; Wnt signaling pathway [GO:0016055]" comp125626_c0_seq1,2073,46.9368,0.89941627,32,96,,2.00E-64,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp125626_c0_seq2,1349,46.6271,0.90159707,0,0,,6.00E-31,Q00690,E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E),E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E),GO:0030029; GO:0007202; GO:0005901; GO:0005905; GO:0030863; GO:0005615; GO:0007157; GO:0016021; GO:0050901; GO:0070492; GO:0048471; GO:0002687; GO:0002092; GO:0070555; GO:0033691; GO:0004888,actin filament-based process; activation of phospholipase C activity; caveola; coated pit; cortical cytoskeleton; extracellular space; heterophilic cell-cell adhesion; integral to membrane; leukocyte tethering or rolling; oligosaccharide binding; perinuclear region of cytoplasm; positive regulation of leukocyte migration; positive regulation of receptor internalization; response to interleukin-1; sialic acid binding; transmembrane signaling receptor activity,PF00008;PF00059;PF00084;,,,,,,,,,LYAM2_MOUSE,Mus musculus (Mouse),actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of receptor internalization [GO:0002092]; response to interleukin-1 [GO:0070555] comp125626_c0_seq4,1196,45.4849,0.84943289,0,0,,8.00E-19,P68638,Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP),Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP),GO:0020002; GO:0016021; GO:0039573; GO:0055036,host cell plasma membrane; integral to membrane; suppression by virus of host complement activation; virion membrane,PF00084;,,,,,,,,,VCP_VACCW,Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)),suppression by virus of host complement activation [GO:0039573] comp125626_c0_seq6,457,43.5449,1.17823161,0,0,,6.00E-08,Q03710,Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Fragment),Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Fragment),GO:0006957; GO:0005576; GO:0006508; GO:0008236,"complement activation, alternative pathway; extracellular region; proteolysis; serine-type peptidase activity",PF00084;,,,,,,,,,CFAB_PIG,Sus scrofa (Pig),"complement activation, alternative pathway [GO:0006957]" comp125628_c0_seq1,810,43.2099,0.63657868,51,0,,2.00E-62,Q9R1A8,E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2),E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2),GO:0005813; GO:0005737; GO:0005925; GO:0016874; GO:0016607; GO:0016567; GO:0008270,centrosome; cytoplasm; focal adhesion; ligase activity; nuclear speck; protein ubiquitination; zinc ion binding,PF00400;,6.00E-50,CHOYP_RFWD2.1.1,,,,,,,RFWD2_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; response to ionizing radiation [GO:0010212] comp125631_c0_seq1,332,45.1807,0.4992549,7,51,,7.00E-11,Q96BV0,Zinc finger protein 775,Zinc finger protein 775,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN775_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125631_c2_seq1,513,41.5205,0.408082,17,23,,5.00E-14,Q9H7R5,Zinc finger protein 665 (Zinc finger protein 160-like),Zinc finger protein 665 (Zinc finger protein 160-like),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN665_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125632_c0_seq1,636,31.6038,0.50736884,1326,7181,,4.00E-27,Q6DRH5,H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10),H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10),GO:0072588; GO:0005730; GO:0060215; GO:0001522; GO:0006364; GO:0030515,box H/ACA RNP complex; nucleolus; primitive hemopoiesis; pseudouridine synthesis; rRNA processing; snoRNA binding,PF04135;,,,9.00E-19,ruditapes_c221,,,,,NOP10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),primitive hemopoiesis [GO:0060215]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364] comp125633_c0_seq4,797,48.3061,0.49651109,1,14,,1.00E-07,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,,,,,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp125633_c0_seq5,756,46.6931,0.48977829,0,0,,8.00E-07,Q98930,Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment),Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment),GO:0008203; GO:0006897; GO:0016021; GO:0006869; GO:0034362,cholesterol metabolic process; endocytosis; integral to membrane; lipid transport; low-density lipoprotein particle,PF00041;PF00057;PF00058;PF15902;PF15901;,,,,,,,,,SORL_CHICK,Gallus gallus (Chicken),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869] comp125638_c0_seq1,1107,41.8248,0.58221719,0,0,,6.00E-10,Q5M9B1,SPRY domain-containing SOCS box protein 3 (SSB-3),SPRY domain-containing SOCS box protein 3 (SSB-3),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF07525;PF00622;,5.00E-116,CHOYP_LOC100377075.1.2,,,,,,,SPSB3_XENLA,Xenopus laevis (African clawed frog),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp125638_c0_seq3,1480,39.9324,0.56240532,14,55,,1.00E-144,Q5E9X6,SPRY domain-containing SOCS box protein 1 (SSB-1),SPRY domain-containing SOCS box protein 1 (SSB-1),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF07525;PF00622;,,,,,,,,,SPSB1_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp125644_c0_seq1,1400,38.2857,0.49765584,646,4884,,9.00E-17,Q95SS8,"Transmembrane protein 70 homolog, mitochondrial","Transmembrane protein 70 homolog, mitochondrial",GO:0032592; GO:0033615,integral to mitochondrial membrane; mitochondrial proton-transporting ATP synthase complex assembly,PF06979;,,,,,,,,,TMM70_DROME,Drosophila melanogaster (Fruit fly),mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615] comp125656_c0_seq1,691,35.89,1.0804082,0,140,,3.00E-21,Q5M7R9,Grainyhead-like protein 2 homolog (Transcription factor CP2-like 3),Grainyhead-like protein 2 homolog (Transcription factor CP2-like 3),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04516;,1.00E-19,CHOYP_ELF1.1.1,,,,,,,GRHL2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"bicellular tight junction assembly [GO:0070830]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell junction assembly [GO:0034329]; epithelial cell morphogenesis [GO:0003382]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp125668_c0_seq3,586,34.8123,0.39681429,0,0,,3.00E-09,Q5EAL6,Transmembrane protein 192,Transmembrane protein 192,GO:0016021; GO:0005770; GO:0005765,integral to membrane; late endosome; lysosomal membrane,PF14802;,3.00E-13,CHOYP_BRAFLDRAFT_122979.1.1,,,,,,,TM192_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp125670_c0_seq3,1793,48.2432,0.53880825,0,0,,3.00E-91,Q9Z1Z3,Epsin-2 (EPS-15-interacting protein 2),Epsin-2 (EPS-15-interacting protein 2),GO:0030128; GO:0006897; GO:0008289; GO:0030100,clathrin coat of endocytic vesicle; endocytosis; lipid binding; regulation of endocytosis,PF01417;,2.00E-86,CHOYP_EPN2.1.1,,,,,,,EPN2_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; regulation of endocytosis [GO:0030100] comp125670_c0_seq4,1795,48.1894,0.53913713,0,0,,1.00E-89,Q8CHU3,Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2),Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2),GO:0007219; GO:0005737; GO:0048568; GO:0006897; GO:0001701; GO:0008289,Notch signaling pathway; cytoplasm; embryonic organ development; endocytosis; in utero embryonic development; lipid binding,PF01417;,,,,,,,,,EPN2_MOUSE,Mus musculus (Mouse),embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; in utero embryonic development [GO:0001701]; Notch signaling pathway [GO:0007219] comp125684_c0_seq2,1636,38.7531,0.3421824,98,129,,3.00E-95,Q5ZL00,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,GO:0072546,ER membrane protein complex,PF07774;PF13360;,2.00E-59,CHOYP_BRAFLDRAFT_72541.1.2,,,,,,,EMC1_CHICK,Gallus gallus (Chicken),protein folding in endoplasmic reticulum [GO:0034975] comp125690_c0_seq1,858,48.0186,0.60248709,35,82,,6.00E-73,Q80TL0,Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA),Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA),GO:0035690; GO:0005737; GO:0046872; GO:0006469; GO:0005730; GO:0035970; GO:0051496; GO:0043234; GO:0006470; GO:0004722,cellular response to drug; cytoplasm; metal ion binding; negative regulation of protein kinase activity; nucleolus; peptidyl-threonine dephosphorylation; positive regulation of stress fiber assembly; protein complex; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,2.00E-17,CHOYP_LOC100694623.1.1,,,,,,,PPM1E_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of stress fiber assembly [GO:0051496]; protein dephosphorylation [GO:0006470] comp125708_c0_seq1,1041,44.6686,0.45333526,936,3338,,6.00E-80,Q8NFH4,Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37),Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37),GO:0005975; GO:0051301; GO:0007059; GO:0000777; GO:0019221; GO:0005829; GO:0015758; GO:0051028; GO:0007067; GO:0007077; GO:0031080; GO:0015031; GO:0010827; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; cell division; chromosome segregation; condensed chromosome kinetochore; cytokine-mediated signaling pathway; cytosol; glucose transport; mRNA transport; mitosis; mitotic nuclear envelope disassembly; nuclear pore outer ring; protein transport; regulation of glucose transport; small molecule metabolic process; transmembrane transport; viral process,PF00400;,,,,,,,,,NUP37_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; sister chromatid cohesion [GO:0007062]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp125715_c0_seq1,559,45.7961,0.54902136,19,4,,7.00E-70,Q6NS57,Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1),Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1),GO:0007256,activation of JNKK activity,PF00400;,3.00E-32,CHOYP_MABP1.2.2,,,,,,,MABP1_MOUSE,Mus musculus (Mouse),activation of JNKK activity [GO:0007256] comp125724_c0_seq1,1015,44.6305,0.59329122,66,123,,2.00E-79,Q29RP8,Histone-lysine N-methyltransferase SUV420H1 (EC 2.1.1.43) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1),Histone-lysine N-methyltransferase KMT5B (EC 2.1.1.43) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1),GO:0005694; GO:0034773; GO:0042799; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"chromosome; histone H4-K20 trimethylation; histone methyltransferase activity (H4-K20 specific); histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,2.00E-70,CHOYP_LOC663776.1.1,,,,,,,SV421_BOVIN,Bos taurus (Bovine),"histone H4-K20 trimethylation [GO:0034773]; muscle organ development [GO:0007517]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp125728_c0_seq1,1349,42.7724,0.47037223,60,122,,2.00E-45,Q8CC12,Codanin-1,Codanin-1,GO:0031497; GO:0005737; GO:0016021; GO:0008156; GO:0005634,chromatin assembly; cytoplasm; integral to membrane; negative regulation of DNA replication; nucleus,PF15296;,5.00E-34,CHOYP_LOC579713.1.1,,,,,,,CDAN1_MOUSE,Mus musculus (Mouse),chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; negative regulation of DNA replication [GO:0008156]; nuclear envelope organization [GO:0006998]; protein localization [GO:0008104] comp125732_c1_seq1,320,39.6875,0.32738718,15,4,,1.00E-21,Q9R194,Cryptochrome-2,Cryptochrome-2,GO:0003913; GO:0006281; GO:0071949; GO:0007623; GO:0005829; GO:0003684; GO:0005576; GO:0005739; GO:0032515; GO:0000122; GO:0005654; GO:0009881; GO:0000988; GO:0006606; GO:0018298; GO:0042752; GO:2000118; GO:0003697; GO:0006351,"DNA photolyase activity; DNA repair; FAD binding; circadian rhythm; cytosol; damaged DNA binding; extracellular region; mitochondrion; negative regulation of phosphoprotein phosphatase activity; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; photoreceptor activity; protein binding transcription factor activity; protein import into nucleus; protein-chromophore linkage; regulation of circadian rhythm; regulation of sodium-dependent phosphate transport; single-stranded DNA binding; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY2_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to insulin [GO:0032868]; transcription, DNA-templated [GO:0006351]" comp125734_c0_seq1,1128,46.2766,0.49907945,0,0,,3.00E-165,Q8BLR2,Copine-4 (Copine IV),Copine-4 (Copine IV),,,PF00168;PF07002;,7.00E-76,CHOYP_BRAFLDRAFT_120970.1.1,,,,,,,CPNE4_MOUSE,Mus musculus (Mouse), comp125734_c0_seq3,1092,45.9707,0.50468954,0,0,,6.00E-21,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,7.00E-76,CHOYP_BRAFLDRAFT_120970.1.1,,,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp125734_c0_seq4,641,48.2059,0.45734272,0,0,,,,,,,,,4.00E-57,CHOYP_BRAFLDRAFT_118500.1.1,,,,,,,,, comp125738_c0_seq1,1374,39.3741,0.83031445,22,57,,4.00E-18,Q01833,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3f fragment],Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3f fragment],GO:0006957; GO:0006958; GO:0004866; GO:0005615; GO:0006954; GO:0010951,"complement activation, alternative pathway; complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; inflammatory response; negative regulation of endopeptidase activity",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_NAJNA,Naja naja (Indian cobra),"complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]" comp125741_c0_seq2,816,42.5245,0.35531299,16,110,,3.00E-64,Q6NRY2,Nucleolar protein 6,Nucleolar protein 6,GO:0003723; GO:0005730,RNA binding; nucleolus,PF03813;,,,,,,,,,NOL6_XENLA,Xenopus laevis (African clawed frog), comp125747_c0_seq2,702,37.1795,0.45461585,490,882,,1.00E-13,Q0MQA6,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a),GO:0042773; GO:0008137; GO:0005743; GO:0070469,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; mitochondrial inner membrane; respiratory chain,PF07347;,,,,,,,,,NDUA7_PONPY,Pongo pygmaeus (Bornean orangutan),ATP synthesis coupled electron transport [GO:0042773] comp125749_c1_seq2,939,44.4089,0.72122844,6,0,,,,,,,,,7.00E-18,CHOYP_LOC100495562.1.2,,,,,,,,, comp125749_c2_seq1,1053,48.2431,0.62430109,0,0,,7.00E-23,Q96LX7,Coiled-coil domain-containing protein 17,Coiled-coil domain-containing protein 17,,,,2.00E-45,CHOYP_BRAFLDRAFT_126355.1.2,,,,,,,CCD17_HUMAN,Homo sapiens (Human), comp125749_c2_seq2,1158,48.6183,0.54154815,16,9,,,,,,,,,2.00E-45,CHOYP_BRAFLDRAFT_126355.1.2,,,,,,,,, comp125750_c0_seq1,992,45.4637,0.55766433,0,0,,5.00E-44,Q80ZI6,E3 ubiquitin-protein ligase LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase),E3 ubiquitin-protein ligase LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase),GO:0005737; GO:0016020; GO:0045806; GO:0051865; GO:0030163; GO:0000209; GO:0015031; GO:0070086; GO:0004842; GO:0046755; GO:0008270,cytoplasm; membrane; negative regulation of endocytosis; protein autoubiquitination; protein catabolic process; protein polyubiquitination; protein transport; ubiquitin-dependent endocytosis; ubiquitin-protein ligase activity; viral budding; zinc ion binding,PF13855;PF00536;,,,,,,,,,LRSM1_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755] comp125750_c0_seq4,805,46.087,0.72943418,0,0,,,,,,,,,2.00E-50,CHOYP_LOC100369519.1.1,,,,,,,,, comp125750_c1_seq1,298,38.5906,0.45635435,4,7,,7.00E-09,Q24307,Apoptosis 2 inhibitor (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2) (dIAP2),Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2),GO:0050829; GO:0043066; GO:0043154; GO:0061057; GO:0006964; GO:0033160; GO:0070534; GO:0007423; GO:0008270,"defense response to Gram-negative bacterium; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidoglycan recognition protein signaling pathway; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; positive regulation of protein import into nucleus, translocation; protein K63-linked ubiquitination; sensory organ development; zinc ion binding",PF00653;,,,,,,,,,IAP2_DROME,Drosophila melanogaster (Fruit fly),"defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]" comp125761_c0_seq2,1173,38.1074,0.94021612,4,58,,2.00E-17,Q866E6,"Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)","Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)",GO:0032580; GO:0008107; GO:0016021; GO:0006486,Golgi cisterna membrane; galactoside 2-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation,PF01531;,,,,,,,,,FUT1_AOTAZ,Aotus azarae (Southern owl monkey) (Aotus azarai),protein glycosylation [GO:0006486] comp125763_c1_seq1,441,35.8277,0.63780992,19,54,,4.00E-06,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp125765_c0_seq1,854,40.0468,0.64336374,2,180,,1.00E-50,Q8K4T5,Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1),Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1),GO:0007254; GO:0008579; GO:0005078; GO:0005737; GO:0000188; GO:0046329; GO:0043508; GO:0035335; GO:0046330; GO:0043507; GO:0030295; GO:0004860; GO:0004725; GO:0008330,JNK cascade; JUN kinase phosphatase activity; MAP-kinase scaffold activity; cytoplasm; inactivation of MAPK activity; negative regulation of JNK cascade; negative regulation of JUN kinase activity; peptidyl-tyrosine dephosphorylation; positive regulation of JNK cascade; positive regulation of JUN kinase activity; protein kinase activator activity; protein kinase inhibitor activity; protein tyrosine phosphatase activity; protein tyrosine/threonine phosphatase activity,PF00782;,,,,,,,,,DUS19_MOUSE,Mus musculus (Mouse),inactivation of MAPK activity [GO:0000188]; JNK cascade [GO:0007254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; protein dephosphorylation [GO:0006470] comp125774_c0_seq1,826,40.5569,0.5351604,29,124,,2.00E-55,Q5U2S3,Zinc finger with UFM1-specific peptidase domain protein,Zinc finger with UFM1-specific peptidase domain protein,GO:0046872,metal ion binding,PF07910;,3.00E-66,CHOYP_AAEL_AAEL013635.1.1,,,,,,,ZUFSP_RAT,Rattus norvegicus (Rat), comp125776_c0_seq1,251,53.3865,0.3986504,9,84,,3.00E-07,Q96CB5,Putative uncharacterized protein C8orf44,Putative uncharacterized protein C8orf44,,,,,,,,,,,,CH044_HUMAN,Homo sapiens (Human), comp125779_c0_seq1,550,36.9091,1.23687701,3,0,,3.00E-18,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,,,,,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp125779_c0_seq2,625,37.44,1.05248807,13,10,,5.00E-16,P27473,Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein),Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein),GO:0005737,cytoplasm,PF07534;,,,,,,,,,IFI44_PANTR,Pan troglodytes (Chimpanzee), comp125788_c0_seq1,724,40.0552,0.6270362,60,465,,2.00E-67,Q7TQA3,Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase reductase 9) (Short-chain dehydrogenase/reductase family 16C member 5),Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase reductase 9) (Short-chain dehydrogenase/reductase family 16C member 5),GO:0005789; GO:0016021; GO:0043616; GO:0042574; GO:0004745; GO:0042572,endoplasmic reticulum membrane; integral to membrane; keratinocyte proliferation; retinal metabolic process; retinol dehydrogenase activity; retinol metabolic process,PF00106;,8.00E-35,CHOYP_RDH10.1.1,5.00E-16,ruditapes_c7765,,,,,RDHE2_MOUSE,Mus musculus (Mouse),keratinocyte proliferation [GO:0043616]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] comp125796_c0_seq1,708,35.0282,0.78393652,2089,18481,,5.00E-12,B0BLS0,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4,GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF10215;,7.00E-23,CHOYP_OST4.1.1,8.00E-14,ruditapes_lrc35564,,,,,OST4_RAT,Rattus norvegicus (Rat), comp125801_c0_seq1,740,43.2432,0.43433318,7,79,,7.00E-19,Q4R6F2,ER membrane-associated RNA degradation protein (Fragment),Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) (Fragment),GO:0016021,integral to membrane,PF13910;,,,,,,,,,CF070_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),multicellular organism development [GO:0007275] comp125806_c0_seq1,854,35.2459,0.53058583,630,1660,,5.00E-22,Q9V9Z1,"39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32)","39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,,,,2.00E-40,ruditapes_c7511,,,,,RM32_DROME,Drosophila melanogaster (Fruit fly),translation [GO:0006412] comp125811_c0_seq1,588,45.2381,0.4409457,46,55,,3.00E-101,A3KP59,Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66),Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66),GO:0051864; GO:0032453; GO:0005506; GO:0045668; GO:0045892; GO:0005730; GO:0005654; GO:0005634; GO:0006351,"histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K4 specific); iron ion binding; negative regulation of osteoblast differentiation; negative regulation of transcription, DNA-dependent; nucleolus; nucleoplasm; nucleus; transcription, DNA-dependent",PF08007;,2.00E-72,CHOYP_LOC577190.1.1,,,,,,,NO66_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-amino acid modification [GO:0018193]; post-translational protein modification [GO:0043687]; ribosome biogenesis [GO:0042254]; transcription, DNA-templated [GO:0006351]" comp125819_c0_seq1,550,39.4545,0.57336298,37,232,,4.00E-29,Q8CEI1,BolA-like protein 3,BolA-like protein 3,GO:0005576,extracellular region,PF01722;,,,,,,,,,BOLA3_MOUSE,Mus musculus (Mouse), comp125819_c0_seq2,526,39.1635,0.61487826,0,13,,6.00E-28,Q53S33,BolA-like protein 3,BolA-like protein 3,GO:0005576,extracellular region,PF01722;,3.00E-19,CHOYP_NEMVEDRAFT_V1G235656.1.1,,,,,,,BOLA3_HUMAN,Homo sapiens (Human), comp125825_c0_seq1,986,44.0162,0.25711521,61,40,,7.00E-39,Q8C3Y4,Kinetochore-associated protein 1,Kinetochore-associated protein 1,GO:0051301; GO:0000777; GO:0005737; GO:0005828; GO:0007067; GO:0007093; GO:0005634; GO:0000922,cell division; condensed chromosome kinetochore; cytoplasm; kinetochore microtubule; mitosis; mitotic cell cycle checkpoint; nucleus; spindle pole,PF10493;,6.00E-13,CHOYP_KNTC1.1.1,,,,,,,KNTC1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067] comp125826_c0_seq1,523,45.8891,0.67569557,530,993,,3.00E-19,Q8C854,Myelin expression factor 2 (MEF-2) (MyEF-2),Myelin expression factor 2 (MEF-2) (MyEF-2),GO:0003677; GO:0003723; GO:0000166; GO:0005634; GO:0006351,"DNA binding; RNA binding; nucleotide binding; nucleus; transcription, DNA-dependent",PF00076;,4.00E-30,CHOYP_MYEF2.1.1,,,,,,,MYEF2_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp125828_c1_seq1,1418,40.5501,0.22494707,4,11,,0,P54646,5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31),5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31),GO:0004679; GO:0005524; GO:0016055; GO:0050405; GO:0047322; GO:0006914; GO:0006853; GO:0007050; GO:0044255; GO:0042149; GO:0006695; GO:0003682; GO:0005829; GO:0006112; GO:0006633; GO:0055089; GO:0042593; GO:0035174; GO:0008286; GO:0008610; GO:0046872; GO:0032007; GO:0043066; GO:0005654; GO:0010508; GO:0045821; GO:0042752; GO:2000505; GO:0042304; GO:0006355; GO:0048511; GO:0044281; GO:0006351,"AMP-activated protein kinase activity; ATP binding; Wnt receptor signaling pathway; [acetyl-CoA carboxylase] kinase activity; [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity; autophagy; carnitine shuttle; cell cycle arrest; cellular lipid metabolic process; cellular response to glucose starvation; cholesterol biosynthetic process; chromatin binding; cytosol; energy reserve metabolic process; fatty acid biosynthetic process; fatty acid homeostasis; glucose homeostasis; histone serine kinase activity; insulin receptor signaling pathway; lipid biosynthetic process; metal ion binding; negative regulation of TOR signaling cascade; negative regulation of apoptotic process; nucleoplasm; positive regulation of autophagy; positive regulation of glycolysis; regulation of circadian rhythm; regulation of energy homeostasis; regulation of fatty acid biosynthetic process; regulation of transcription, DNA-dependent; rhythmic process; small molecule metabolic process; transcription, DNA-dependent",PF16579;PF00069;,4.00E-30,CHOYP_BRAFLDRAFT_239705.1.1,,,,,,,AAPK2_HUMAN,Homo sapiens (Human),"carnitine shuttle [GO:0006853]; cell cycle arrest [GO:0007050]; cellular response to drug [GO:0035690]; cellular response to glucose starvation [GO:0042149]; cellular response to nutrient levels [GO:0031669]; cellular response to prostaglandin E stimulus [GO:0071380]; cholesterol biosynthetic process [GO:0006695]; fatty acid biosynthetic process [GO:0006633]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; histone-serine phosphorylation [GO:0035404]; intracellular signal transduction [GO:0035556]; lipid biosynthetic process [GO:0008610]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of TOR signaling [GO:0032007]; positive regulation of autophagy [GO:0010508]; positive regulation of glycolytic process [GO:0045821]; positive regulation of macroautophagy [GO:0016239]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; response to muscle activity [GO:0014850]; response to stress [GO:0006950]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp125828_c1_seq3,1475,41.2203,0.2407177,8,7,,1.00E-100,O94168,Carbon catabolite-derepressing protein kinase (EC 2.7.11.1),Carbon catabolite-derepressing protein kinase (EC 2.7.11.1),GO:0005524; GO:0005975; GO:0031965; GO:0004674,ATP binding; carbohydrate metabolic process; nuclear membrane; protein serine/threonine kinase activity,PF16579;PF00069;PF08587;,3.00E-138,CHOYP_SNF1A.1.1,,,,,,,SNF1_CANTR,Candida tropicalis (Yeast),carbohydrate metabolic process [GO:0005975] comp125830_c0_seq1,799,43.3041,0.48217052,14,12,,,,,,,,,7.00E-11,CHOYP_LOC577190.1.1,,,,,,,,, comp125830_c0_seq2,907,43.1092,0.47514448,29,52,,4.00E-09,C3XRY1,Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66),Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66),GO:0051864; GO:0032453; GO:0005506; GO:0045892; GO:0005634; GO:0006351,"histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K4 specific); iron ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF08007;,,,,,,,,,NO66_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),"chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-amino acid modification [GO:0018193]; post-translational protein modification [GO:0043687]; ribosome biogenesis [GO:0042254]; transcription, DNA-templated [GO:0006351]" comp125835_c0_seq1,728,42.9945,0.24314229,36,125,,7.00E-35,Q07326,Phosphatidylinositol-glycan biosynthesis class F protein (PIG-F) (GPI11 homolog),Phosphatidylinositol-glycan biosynthesis class F protein (PIG-F) (GPI11 homolog),GO:0006501; GO:0005789; GO:0004307; GO:0016021; GO:0016254,C-terminal protein lipidation; endoplasmic reticulum membrane; ethanolaminephosphotransferase activity; integral to membrane; preassembly of GPI anchor in ER membrane,PF06699;,,,,,,,,,PIGF_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp125840_c0_seq1,1239,40.9201,0.50906368,314,2200,,1.00E-168,Q9JJT0,RNA 3'-terminal phosphate cyclase-like protein,RNA 3'-terminal phosphate cyclase-like protein,GO:0003824; GO:0005730; GO:0006364,catalytic activity; nucleolus; rRNA processing,PF01137;PF05189;,9.00E-126,CHOYP_RCL1.1.1,,,,,,,RCL1_MOUSE,Mus musculus (Mouse),"endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; rRNA processing [GO:0006364]" comp125841_c0_seq1,543,52.1179,0.35356584,23,29,,2.00E-19,A2BGR3,DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like),DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like),GO:0005524; GO:0003677; GO:0051301; GO:0000777; GO:0004386; GO:0016539; GO:0007067,ATP binding; DNA binding; cell division; condensed chromosome kinetochore; helicase activity; intein-mediated protein splicing; mitosis,PF00271;PF00176;,,,,,,,,,ERC6L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539]; mitotic nuclear division [GO:0007067] comp125841_c1_seq1,1075,44.3721,0.47754346,29,79,,7.00E-131,A2BGR3,DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like),DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like),GO:0005524; GO:0003677; GO:0051301; GO:0000777; GO:0004386; GO:0016539; GO:0007067,ATP binding; DNA binding; cell division; condensed chromosome kinetochore; helicase activity; intein-mediated protein splicing; mitosis,PF00271;PF00176;,3.00E-118,CHOYP_LOC100373376.1.1,,,,,,,ERC6L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539]; mitotic nuclear division [GO:0007067] comp125843_c0_seq1,256,49.2188,0.90745395,6,9,,3.00E-11,P48768,Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0033280; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; plasma membrane; response to vitamin D; telencephalon development,PF03160;PF01699;PF16494;,,,,,,,,,NAC2_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp125843_c2_seq1,224,50,1.01255634,6,9,,,,,,,,,1.00E-26,CHOYP_LOC100371845.3.3,2.00E-28,ruditapes_c29564,,,,,,, comp125847_c0_seq1,1770,42.3164,0.50869625,1901,90,,4.00E-64,B1H283,Uncharacterized protein C1orf177 homolog,Lymphocyte expansion molecule,,,,1.00E-170,CHOYP_LOC100374808.1.1,,,,,,,CA177_RAT,Rattus norvegicus (Rat),"CD8-positive, alpha-beta T cell proliferation [GO:0035740]; positive regulation of cell proliferation [GO:0008284]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of oxidative phosphorylation [GO:1903862]" comp125851_c0_seq1,911,36.0044,0.681819,7517,13251,,3.00E-15,Q0MQD6,"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit)","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit)",GO:0016021; GO:0005743; GO:0055114; GO:0070469,integral to membrane; mitochondrial inner membrane; oxidation-reduction process; respiratory chain,PF09781;,,,,,,,,,NDUB5_PONPY,Pongo pygmaeus (Bornean orangutan),oxidation-reduction process [GO:0055114] comp125853_c0_seq1,1161,45.1335,0.4998298,52,180,,2.00E-123,Q3UHX9,Uncharacterized protein C9orf114 homolog,Putative methyltransferase C9orf114 homolog (EC 2.1.1.-),,,PF02598;,5.00E-72,CHOYP_CI114.1.1,,,,,,,CI114_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell division [GO:0051301] comp125854_c0_seq1,496,42.7419,0.80075513,9,40,,2.00E-44,Q504A5,Probable thiopurine S-methyltransferase (Thiopurine methyltransferase) (EC 2.1.1.67),Probable thiopurine S-methyltransferase (Thiopurine methyltransferase) (EC 2.1.1.67),GO:0005737; GO:0008119,cytoplasm; thiopurine S-methyltransferase activity,PF05724;,,,,,,,,,TPMT_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nucleobase-containing compound metabolic process [GO:0006139] comp125856_c0_seq1,265,34.3396,1.02803396,41,39,,,,,,,,,,,1.00E-12,ruditapes_lrc33589,,,,,,, comp125856_c0_seq2,247,39.2713,1.05713583,0,41,,,,,,,,,7.00E-11,CHOYP_TBB.4.7,2.00E-16,ruditapes2_lrc4170,,,,,,, comp125860_c0_seq1,708,40.9605,0.23827404,12,92,,9.00E-77,Q5E9T8,Mevalonate kinase (MK) (EC 2.7.1.36),Mevalonate kinase (MK) (EC 2.7.1.36),GO:0005524; GO:0006695; GO:0019287; GO:0004496; GO:0005777,"ATP binding; cholesterol biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; mevalonate kinase activity; peroxisome",PF08544;PF00288;,1.00E-13,CHOYP_BRAFLDRAFT_219207.1.1,,,,,,,KIME_BOVIN,Bos taurus (Bovine),"cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]" comp125863_c0_seq1,760,42.3684,0.47384889,22,37,,3.00E-68,Q9GKS6,Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (Fragment),Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D) (Fragment),GO:0005524; GO:0019829; GO:0005789; GO:0016021; GO:0000287; GO:0004012; GO:0005886,ATP binding; cation-transporting ATPase activity; endoplasmic reticulum membrane; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity; plasma membrane,PF16212;,,,,,,,,,AT10D_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp125863_c1_seq1,1176,41.3265,0.56085813,48,17,,5.00E-163,P70704,Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II),Phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1),GO:0005524; GO:0019829; GO:0042584; GO:0005783; GO:0016021; GO:0000287; GO:0004012; GO:0005886,ATP binding; cation-transporting ATPase activity; chromaffin granule membrane; endoplasmic reticulum; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity; plasma membrane,PF00122;PF16212;PF16209;,1.00E-180,CHOYP_AT8A1.2.2,,,,,,,AT8A1_MOUSE,Mus musculus (Mouse),Golgi vesicle budding [GO:0048194]; learning [GO:0007612]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092] comp125868_c0_seq1,1475,46.1695,0.58562362,115,90,,0,P43090,"5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2)","5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2)",GO:0003870; GO:0005743; GO:0005759; GO:0006782; GO:0030170; GO:0001666,5-aminolevulinate synthase activity; mitochondrial inner membrane; mitochondrial matrix; protoporphyrinogen IX biosynthetic process; pyridoxal phosphate binding; response to hypoxia,PF00155;PF09029;,5.00E-98,CHOYP_AAEL_AAEL007787.1.1,,,,,,,HEM0_OPSTA,Opsanus tau (Oyster toadfish) (Gadus tau),protoporphyrinogen IX biosynthetic process [GO:0006782]; response to hypoxia [GO:0001666] comp125868_c2_seq1,587,44.1227,0.59627947,23,15,,,,,,,,,,,1.00E-16,ruditapes_c21491,,,,,,, comp125870_c0_seq1,959,38.7904,0.61403576,199,18,,6.00E-63,Q4FZY0,EF-hand domain-containing protein D2 (Swiprosin-1),EF-hand domain-containing protein D2 (Swiprosin-1),GO:0005509; GO:0045121,calcium ion binding; membrane raft,PF13499;,1.00E-64,CHOYP_LOC100375509.1.1,,,,,,,EFHD2_RAT,Rattus norvegicus (Rat), comp125871_c2_seq1,734,40.1907,0.60810924,22,134,,1.00E-10,Q8CIG9,F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8),F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8),,,PF12937;,,,,,,,,,FBXL8_MOUSE,Mus musculus (Mouse), comp125873_c0_seq1,770,38.7013,0.67074289,33,78,,3.00E-06,Q04861,Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit],Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit],GO:0002755; GO:0051059; GO:0035419; GO:0007250; GO:0005829; GO:0045087; GO:0001818; GO:0050728; GO:0045083; GO:0045892; GO:0005634; GO:0045944; GO:0043565; GO:0003700; GO:0035681; GO:0034134; GO:0035682; GO:0034138; GO:0034142; GO:0034146; GO:0034154; GO:0006351,"MyD88-dependent toll-like receptor signaling pathway; NF-kappaB binding; activation of MAPK activity involved in innate immune response; activation of NF-kappaB-inducing kinase activity; cytosol; innate immune response; negative regulation of cytokine production; negative regulation of inflammatory response; negative regulation of interleukin-12 biosynthetic process; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; toll-like receptor 15 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 21 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 7 signaling pathway; transcription, DNA-dependent",PF00023;PF12796;PF00531;PF16179;PF00554;,,,2.00E-15,ruditapes_c28557,,,,,NFKB1_CHICK,Gallus gallus (Chicken),cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994] comp125873_c0_seq2,324,47.5309,0.27407918,17,24,,,,,,,,,,,1.00E-25,ruditapes_c28496,,,,,,, comp125883_c0_seq1,2488,44.8955,0.64769408,0,0,,0,Q01433,AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L),AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L),GO:0003876; GO:0032264; GO:0005829; GO:0046872; GO:0006144; GO:0006163; GO:0043101,AMP deaminase activity; IMP salvage; cytosol; metal ion binding; purine nucleobase metabolic process; purine nucleotide metabolic process; purine-containing compound salvage,PF00962;,0,CHOYP_AMPD2.1.2,,,,,,,AMPD2_HUMAN,Homo sapiens (Human),AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; purine-containing compound salvage [GO:0043101] comp125883_c0_seq2,2506,44.8524,0.6522681,0,0,,0,O80452,AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1),AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1),GO:0003876; GO:0005524; GO:0032264; GO:0005829; GO:0009793; GO:0005783; GO:0031307; GO:0046872; GO:0005634; GO:0009737,AMP deaminase activity; ATP binding; IMP salvage; cytosol; embryo development ending in seed dormancy; endoplasmic reticulum; integral to mitochondrial outer membrane; metal ion binding; nucleus; response to abscisic acid stimulus,PF00962;,,,,,,,,,AMPD_ARATH,Arabidopsis thaliana (Mouse-ear cress),embryo development ending in seed dormancy [GO:0009793]; IMP salvage [GO:0032264]; response to abscisic acid [GO:0009737] comp125883_c0_seq4,2554,44.7142,0.65157554,0,0,,0,O80452,AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1),AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1),GO:0003876; GO:0005524; GO:0032264; GO:0005829; GO:0009793; GO:0005783; GO:0031307; GO:0046872; GO:0005634; GO:0009737,AMP deaminase activity; ATP binding; IMP salvage; cytosol; embryo development ending in seed dormancy; endoplasmic reticulum; integral to mitochondrial outer membrane; metal ion binding; nucleus; response to abscisic acid stimulus,PF00962;,,,,,,,,,AMPD_ARATH,Arabidopsis thaliana (Mouse-ear cress),embryo development ending in seed dormancy [GO:0009793]; IMP salvage [GO:0032264]; response to abscisic acid [GO:0009737] comp125883_c0_seq5,2536,44.7555,0.64706514,0,0,,0,Q01433,AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L),AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L),GO:0003876; GO:0032264; GO:0005829; GO:0046872; GO:0006144; GO:0006163; GO:0043101,AMP deaminase activity; IMP salvage; cytosol; metal ion binding; purine nucleobase metabolic process; purine nucleotide metabolic process; purine-containing compound salvage,PF00962;,,,,,,,,,AMPD2_HUMAN,Homo sapiens (Human),AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; purine-containing compound salvage [GO:0043101] comp125883_c0_seq6,2518,44.7975,0.65084912,0,0,,0,P15274,AMP deaminase (EC 3.5.4.6) (Myoadenylate deaminase),AMP deaminase (EC 3.5.4.6) (Myoadenylate deaminase),GO:0003876; GO:0032264; GO:0006178; GO:0046872; GO:0006163,AMP deaminase activity; IMP salvage; guanine salvage; metal ion binding; purine nucleotide metabolic process,PF00962;,0,CHOYP_AMPD2.1.2,,,,,,,AMPD_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),guanine salvage [GO:0006178]; IMP salvage [GO:0032264]; purine nucleotide metabolic process [GO:0006163] comp125884_c0_seq1,853,45.721,0.27560279,73,15,,1.00E-42,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp125888_c0_seq1,577,44.3674,0.49904559,23,29,,2.00E-26,Q92574,Hamartin (Tuberous sclerosis 1 protein),Hamartin (Tuberous sclerosis 1 protein),GO:0030695; GO:0033596; GO:0032862; GO:0055007; GO:0005938; GO:0007050; GO:0030030; GO:0007160; GO:0021987; GO:0030426; GO:0021766; GO:0008286; GO:0043231; GO:0001822; GO:0030027; GO:0016020; GO:0042552; GO:0032007; GO:0008285; GO:0045792; GO:0017148; GO:0001843; GO:0051894; GO:0006813; GO:0051291; GO:0050821; GO:0006407; GO:0043666; GO:0045859; GO:0051492; GO:0050808,GTPase regulator activity; TSC1-TSC2 complex; activation of Rho GTPase activity; cardiac muscle cell differentiation; cell cortex; cell cycle arrest; cell projection organization; cell-matrix adhesion; cerebral cortex development; growth cone; hippocampus development; insulin receptor signaling pathway; intracellular membrane-bounded organelle; kidney development; lamellipodium; membrane; myelination; negative regulation of TOR signaling cascade; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of translation; neural tube closure; positive regulation of focal adhesion assembly; potassium ion transport; protein heterooligomerization; protein stabilization; rRNA export from nucleus; regulation of phosphoprotein phosphatase activity; regulation of protein kinase activity; regulation of stress fiber assembly; synapse organization,PF04388;,1.00E-11,CHOYP_TSC1.1.1,,,,,,,TSC1_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; cardiac muscle cell differentiation [GO:0055007]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of macroautophagy [GO:0016242]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; potassium ion transport [GO:0006813]; protein heterooligomerization [GO:0051291]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] comp125895_c1_seq1,1384,39.9566,0.57274035,17,185,,2.00E-72,Q8BPM0,Disheveled-associated activator of morphogenesis 1,Disheveled-associated activator of morphogenesis 1,GO:0030036; GO:0005737; GO:0005886; GO:0001725,actin cytoskeleton organization; cytoplasm; plasma membrane; stress fiber,PF06367;PF06371;PF02181;,,,,,,,,,DAAM1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036] comp125898_c0_seq1,539,45.0835,0.56320594,32,33,,5.00E-38,Q8CIK8,E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201),E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201),GO:0006281; GO:0097371; GO:0016605; GO:0005737; GO:0031571; GO:0005634; GO:0002039; GO:0010212; GO:0004842; GO:0008270,DNA repair; MDM2/MDM4 family protein binding; PML body; cytoplasm; mitotic G1 DNA damage checkpoint; nucleus; p53 binding; response to ionizing radiation; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,2.00E-35,CHOYP_BRAFLDRAFT_121302.1.2,,,,,,,RFWD3_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mitotic G1 DNA damage checkpoint [GO:0031571]; positive regulation of defense response to virus by host [GO:0002230]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; xenophagy [GO:0098792] comp125905_c0_seq1,826,38.9831,0.67167611,3459,19700,,4.00E-14,P12075,"Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb) (Cytochrome c oxidase subunit VIA*)","Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb) (Cytochrome c oxidase subunit VIA*)",GO:0004129; GO:0046872; GO:0005743; GO:0043434,cytochrome-c oxidase activity; metal ion binding; mitochondrial inner membrane; response to peptide hormone stimulus,PF01215;,,,,,,,,,COX5B_RAT,Rattus norvegicus (Rat),response to hormone [GO:0009725]; response to peptide hormone [GO:0043434] comp125910_c1_seq1,628,46.6561,0.35218454,0,0,,,,,,,,,2.00E-30,CHOYP_BRAFLDRAFT_117629.1.2,,,,,,,,, comp125910_c1_seq2,1869,44.8368,0.35230455,81,21,,1.00E-68,Q8CE72,Uncharacterized protein C5orf42 homolog,Uncharacterized protein C5orf42 homolog,GO:0016021,integral to membrane,PF15392;,1.00E-31,CHOYP_BRAFLDRAFT_117629.2.2,,,,,,,CE042_MOUSE,Mus musculus (Mouse),cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; palate development [GO:0060021]; protein localization to ciliary transition zone [GO:1904491]; ventricular septum development [GO:0003281] comp125911_c0_seq1,1312,41.7683,0.36837205,128,182,,7.00E-51,O75340,Programmed cell death protein 6 (Apoptosis-linked gene 2 protein) (Probable calcium-binding protein ALG-2),Programmed cell death protein 6 (Apoptosis-linked gene 2 protein) (Probable calcium-binding protein ALG-2),GO:0006919; GO:0001525; GO:0097190; GO:0060090; GO:0005509; GO:0033554; GO:0031410; GO:0005783; GO:0005789; GO:0005768; GO:0006886; GO:0032007; GO:0051898; GO:0030948; GO:0031965; GO:0005634; GO:0045766; GO:0010595; GO:0001938; GO:0051592; GO:0036324,"activation of cysteine-type endopeptidase activity involved in apoptotic process; angiogenesis; apoptotic signaling pathway; binding, bridging; calcium ion binding; cellular response to stress; cytoplasmic vesicle; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; intracellular protein transport; negative regulation of TOR signaling cascade; negative regulation of protein kinase B signaling cascade; negative regulation of vascular endothelial growth factor receptor signaling pathway; nuclear membrane; nucleus; positive regulation of angiogenesis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; response to calcium ion; vascular endothelial growth factor receptor-2 signaling pathway",PF13202;PF13499;,2.00E-71,CHOYP_LOC100370201.1.1,3.00E-129,ruditapes_c1980,,,,,PDCD6_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] comp125913_c0_seq1,727,33.8377,0.49709893,4456,15587,,2.00E-34,P62309,Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG),Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG),GO:0003723; GO:0008380; GO:0005689; GO:0005683; GO:0071013; GO:0006397,RNA binding; RNA splicing; U12-type spliceosomal complex; U7 snRNP; catalytic step 2 spliceosome; mRNA processing,PF01423;,7.00E-42,CHOYP_RUXG.2.2,5.00E-67,ruditapes_c6411,,,,,RUXG_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]" comp125919_c0_seq3,1063,37.0649,0.39063313,33,126,,2.00E-59,P49914,"5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)","5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)",GO:0030272; GO:0005524; GO:0005794; GO:0005829; GO:0005542; GO:0009396; GO:0015942; GO:0005886; GO:0046653,5-formyltetrahydrofolate cyclo-ligase activity; ATP binding; Golgi apparatus; cytosol; folic acid binding; folic acid-containing compound biosynthetic process; formate metabolic process; plasma membrane; tetrahydrofolate metabolic process,PF01812;,,,,,,,,,MTHFS_HUMAN,Homo sapiens (Human),folic acid catabolic process [GO:0046657]; folic acid-containing compound biosynthetic process [GO:0009396]; folic acid metabolic process [GO:0046655]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] comp125921_c0_seq1,643,38.2582,0.39351035,16,64,,1.00E-11,Q9Y2W6,Tudor and KH domain-containing protein (Tudor domain-containing protein 2),Tudor and KH domain-containing protein (Tudor domain-containing protein 2),GO:0043046; GO:0003723; GO:0030154; GO:0009566; GO:0031047; GO:0007140; GO:0005739; GO:0071546; GO:0071547; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; RNA binding; cell differentiation; fertilization; gene silencing by RNA; male meiosis; mitochondrion; pi-body; piP-body; piRNA metabolic process; spermatogenesis,PF00013;PF00567;,,,,,,,,,TDRKH_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp125921_c1_seq1,1017,45.1327,0.5650149,24,67,,3.00E-57,Q80VL1,Tudor and KH domain-containing protein (Tudor domain-containing protein 2),Tudor and KH domain-containing protein (Tudor domain-containing protein 2),GO:0043046; GO:0003723; GO:0030154; GO:0009566; GO:0031047; GO:0007140; GO:0005739; GO:0071546; GO:0071547; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; RNA binding; cell differentiation; fertilization; gene silencing by RNA; male meiosis; mitochondrion; pi-body; piP-body; piRNA metabolic process; spermatogenesis,PF00013;PF00567;,,,,,,,,,TDRKH_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp125923_c0_seq1,2222,42.1692,0.33160242,88,220,,0,Q59HJ6,"Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)","Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)",GO:0043531; GO:0005524; GO:0004176; GO:0051880; GO:0034599; GO:0051131; GO:0006515; GO:0070362; GO:0070361; GO:0042645; GO:0007005; GO:0070407; GO:0051260; GO:0090296; GO:0001666; GO:0043565; GO:0004252; GO:0003697; GO:0003727,ADP binding; ATP binding; ATP-dependent peptidase activity; G-quadruplex DNA binding; cellular response to oxidative stress; chaperone-mediated protein complex assembly; misfolded or incompletely synthesized protein catabolic process; mitochondrial heavy strand promoter anti-sense binding; mitochondrial light strand promoter anti-sense binding; mitochondrial nucleoid; mitochondrion organization; oxidation-dependent protein catabolic process; protein homooligomerization; regulation of mitochondrial DNA replication; response to hypoxia; sequence-specific DNA binding; serine-type endopeptidase activity; single-stranded DNA binding; single-stranded RNA binding,PF00004;PF05362;PF02190;,2.00E-168,CHOYP_LONM.1.1,,,,,,,LONM_BOVIN,Bos taurus (Bovine),cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion organization [GO:0007005]; modification-dependent protein catabolic process [GO:0019941]; oxidation-dependent protein catabolic process [GO:0070407]; regulation of mitochondrial DNA replication [GO:0090296] comp125933_c0_seq1,410,46.8293,0.98497318,1,76,,2.00E-16,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp125937_c0_seq2,1552,42.7835,0.51671479,68,49,,1.00E-10,Q6DGE9,Protein unc-45 homolog B (Unc-45B) (UNC45-related protein),Protein unc-45 homolog B (Unc-45B) (UNC45-related protein),GO:0030018; GO:0048738; GO:0030239; GO:0048471; GO:0007519,Z disc; cardiac muscle tissue development; myofibril assembly; perinuclear region of cytoplasm; skeletal muscle tissue development,PF11701;,,,,,,,,,UN45B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cardiac muscle tissue development [GO:0048738]; lens development in camera-type eye [GO:0002088]; muscle fiber development [GO:0048747]; myofibril assembly [GO:0030239]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue development [GO:0007519] comp125945_c0_seq1,1724,38.7471,0.7493625,918,2304,,5.00E-44,Q5R1W5,"Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)","Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)",GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166,RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding,PF00076;,,,,,,,,,SRSF2_PANTR,Pan troglodytes (Chimpanzee),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp125945_c0_seq2,1347,42.6875,0.76020795,98,427,,1.00E-44,Q5R1W5,"Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)","Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)",GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166,RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding,PF00076;,6.00E-59,CHOYP_LOC100369357.1.1,4.00E-78,ruditapes_c11316,,,,,SRSF2_PANTR,Pan troglodytes (Chimpanzee),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp125947_c1_seq1,1589,40.9692,0.52590317,93,273,,6.00E-19,Q6NRW0,Mdm2-binding protein,Mdm2-binding protein,GO:0007050,cell cycle arrest,PF14920;PF14919;PF14918;,4.00E-11,CHOYP_MTBP.1.1,,,,,,,MTBP_XENLA,Xenopus laevis (African clawed frog),cell cycle arrest [GO:0007050] comp125948_c0_seq2,993,41.289,0.35819856,17,9,,6.00E-16,Q80X90,Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin),Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin),GO:0030018; GO:0005938; GO:0005737; GO:0005925; GO:0007519; GO:0001725,Z disc; cell cortex; cytoplasm; focal adhesion; skeletal muscle tissue development; stress fiber,PF00307;PF00630;,,,,,,,,,FLNB_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; skeletal muscle tissue development [GO:0007519] comp125948_c0_seq3,827,44.3773,0.32140985,0,5,,7.00E-16,Q8VHX6,Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),GO:0030018; GO:0003779; GO:0015629; GO:0030029; GO:0048747; GO:0042383,Z disc; actin binding; actin cytoskeleton; actin filament-based process; muscle fiber development; sarcolemma,PF00307;PF00630;,,,,,,,,,FLNC_MOUSE,Mus musculus (Mouse),actin filament-based process [GO:0030029]; muscle fiber development [GO:0048747] comp125949_c0_seq1,1047,42.6934,0.90453716,33,83,,3.00E-11,P41047,"Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]","Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]",GO:0070231; GO:0006919; GO:0060555; GO:0060554; GO:0005901; GO:0030644; GO:0033554; GO:0060205; GO:0048388; GO:0009897; GO:0005615; GO:0070062; GO:0008625; GO:0006955; GO:0006925; GO:0016021; GO:0043202; GO:0070265; GO:0016525; GO:0000122; GO:0005634; GO:0048471; GO:0043123; GO:0043065; GO:0008284; GO:2000353; GO:0045742; GO:0043525; GO:0070848; GO:0032496; GO:0046666; GO:0006351,"T cell apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of necroptosis by extracellular signals; activation of necroptosis of activated-T cells; caveola; cellular chloride ion homeostasis; cellular response to stress; cytoplasmic membrane-bounded vesicle lumen; endosomal lumen acidification; external side of plasma membrane; extracellular space; extracellular vesicular exosome; extrinsic apoptotic signaling pathway via death domain receptors; immune response; inflammatory cell apoptotic process; integral to membrane; lysosomal lumen; necrotic cell death; negative regulation of angiogenesis; negative regulation of transcription from RNA polymerase II promoter; nucleus; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of endothelial cell apoptotic process; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of neuron apoptotic process; response to growth factor stimulus; response to lipopolysaccharide; retinal cell programmed cell death; transcription, DNA-dependent",PF00229;,,,,,,,,,TNFL6_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular chloride ion homeostasis [GO:0030644]; endosomal lumen acidification [GO:0048388]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; immune response [GO:0006955]; inflammatory cell apoptotic process [GO:0006925]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron apoptotic process [GO:0043525]; response to growth factor [GO:0070848]; response to lipopolysaccharide [GO:0032496]; retinal cell programmed cell death [GO:0046666]; T cell apoptotic process [GO:0070231]; transcription, DNA-templated [GO:0006351]" comp125957_c0_seq1,517,37.5242,0.3384159,11,12,,,,,,,,,6.00E-22,CHOYP_LOC594533.1.1,,,,,,,,, comp125957_c1_seq1,435,41.6092,0.75043426,12,14,,,,,,,,,6.00E-15,CHOYP_LOC594533.1.1,,,,,,,,, comp125957_c3_seq1,937,40.2348,0.2945815,0,0,,4.00E-33,Q8IYE1,Coiled-coil domain-containing protein 13,Coiled-coil domain-containing protein 13,,,,,,,,,,,,CCD13_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; nonmotile primary cilium assembly [GO:0035058] comp125961_c0_seq2,1552,41.817,0.42939545,69,28,,5.00E-74,Q8BUG5,Calcyphosin-2 (Calcyphosine-2),Calcyphosin-2 (Calcyphosine-2),GO:0005509,calcium ion binding,,7.00E-40,CHOYP_LOC579381.1.1,,,,,,,CAYP2_MOUSE,Mus musculus (Mouse), comp125963_c0_seq3,413,42.1308,0.40903557,0,8,,4.00E-07,A4IIE8,Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4),Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4),GO:0030306; GO:0017137; GO:0005509; GO:0032154; GO:0000910; GO:0030139; GO:0030496; GO:0042803; GO:0055038; GO:0006810,ADP-ribosylation factor binding; Rab GTPase binding; calcium ion binding; cleavage furrow; cytokinesis; endocytic vesicle; midbody; protein homodimerization activity; recycling endosome membrane; transport,PF09457;,,,,,,,,,RFIP4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cytokinesis [GO:0000910]; transport [GO:0006810] comp125963_c1_seq1,230,40.8696,0.55317138,2,18,,6.00E-10,Q3LGD4,Rab11 family-interacting protein 4A (FIP4-Rab11) (Rab11-FIP4-A) (zRab11-FIP4-A),Rab11 family-interacting protein 4A (FIP4-Rab11) (Rab11-FIP4-A) (zRab11-FIP4-A),GO:0030306; GO:0017137; GO:0005509; GO:0032154; GO:0000910; GO:0030139; GO:0048592; GO:0030496; GO:0042803; GO:0055038; GO:0051726; GO:0043565; GO:0003700; GO:0006810,ADP-ribosylation factor binding; Rab GTPase binding; calcium ion binding; cleavage furrow; cytokinesis; endocytic vesicle; eye morphogenesis; midbody; protein homodimerization activity; recycling endosome membrane; regulation of cell cycle; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transport,PF07716;PF09457;,,,,,,,,,RFP4A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cytokinesis [GO:0000910]; eye morphogenesis [GO:0048592]; regulation of cell cycle [GO:0051726]; transport [GO:0006810] comp125963_c2_seq2,365,43.8356,0.53095176,0,31,,7.00E-08,Q8BQP8,Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (mRab11-FIP4A),Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (mRab11-FIP4A),GO:0030306; GO:0017137; GO:0005509; GO:0032154; GO:0000910; GO:0030139; GO:0030496; GO:0042803; GO:0055038; GO:0006810,ADP-ribosylation factor binding; Rab GTPase binding; calcium ion binding; cleavage furrow; cytokinesis; endocytic vesicle; midbody; protein homodimerization activity; recycling endosome membrane; transport,PF09457;,,,,,,,,,RFIP4_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; neural retina development [GO:0003407]; positive regulation of G1 to G0 transition [GO:1903452]; transport [GO:0006810] comp125966_c0_seq1,1911,39.1941,0.34819357,48,285,,3.00E-28,Q02357,Ankyrin-1 (ANK-1) (Erythrocyte ankyrin),Ankyrin-1 (ANK-1) (Erythrocyte ankyrin),GO:0030863; GO:0048821; GO:0016020; GO:0015672; GO:0006779; GO:0016529; GO:0007165; GO:0014731,cortical cytoskeleton; erythrocyte development; membrane; monovalent inorganic cation transport; porphyrin-containing compound biosynthetic process; sarcoplasmic reticulum; signal transduction; spectrin-associated cytoskeleton,PF12796;PF00531;PF00791;,,,,,,,,,ANK1_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; iron ion homeostasis [GO:0055072]; monovalent inorganic cation transport [GO:0015672]; porphyrin-containing compound biosynthetic process [GO:0006779]; protein targeting to plasma membrane [GO:0072661]; signal transduction [GO:0007165] comp125971_c0_seq1,1209,38.2961,0.33879662,48,145,,8.00E-83,Q5BIS9,5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb),5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb),GO:0006633; GO:0005634; GO:0010628; GO:0004672,fatty acid biosynthetic process; nucleus; positive regulation of gene expression; protein kinase activity,PF16561;PF04739;,3.00E-75,CHOYP_PRKAB2.1.1,,,,,,,AAKB1_BOVIN,Bos taurus (Bovine),fatty acid biosynthetic process [GO:0006633]; positive regulation of gene expression [GO:0010628]; regulation of protein kinase activity [GO:0045859]; signal transduction [GO:0007165] comp125981_c0_seq1,1452,46.281,0.45045904,104,123,,4.00E-152,Q969N2,GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein),GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein),GO:0006501; GO:0003923; GO:0042765; GO:0016255; GO:0016023; GO:0051402; GO:0030182,C-terminal protein lipidation; GPI-anchor transamidase activity; GPI-anchor transamidase complex; attachment of GPI anchor to protein; cytoplasmic membrane-bounded vesicle; neuron apoptotic process; neuron differentiation,PF04113;,5.00E-47,CHOYP_LOC100374276.1.1,,,,,,,PIGT_HUMAN,Homo sapiens (Human),attachment of GPI anchor to protein [GO:0016255]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182] comp125983_c0_seq1,881,45.857,0.36768973,59,34,,5.00E-26,Q99698,Lysosomal-trafficking regulator (Beige homolog),Lysosomal-trafficking regulator (Beige homolog),GO:0002456; GO:0007596; GO:0005829; GO:0042742; GO:0042832; GO:0051607; GO:0032510; GO:0030595; GO:0007040; GO:0033364; GO:0032438; GO:0015630; GO:0007017; GO:0042267; GO:0002446; GO:0055091; GO:0006644; GO:0032816; GO:0042493; GO:0033299,T cell mediated immunity; blood coagulation; cytosol; defense response to bacterium; defense response to protozoan; defense response to virus; endosome to lysosome transport via multivesicular body sorting pathway; leukocyte chemotaxis; lysosome organization; mast cell secretory granule organization; melanosome organization; microtubule cytoskeleton; microtubule-based process; natural killer cell mediated cytotoxicity; neutrophil mediated immunity; phospholipid homeostasis; phospholipid metabolic process; positive regulation of natural killer cell activation; response to drug; secretion of lysosomal enzymes,PF02138;PF14844;PF00400;,,,,,,,,,LYST_HUMAN,Homo sapiens (Human),defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031] comp125989_c0_seq1,715,38.7413,0.83027782,108,80,,2.00E-64,P12700,Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I),Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I),GO:0009060; GO:0004129; GO:0009055; GO:0020037; GO:0016021; GO:0005506; GO:0005743; GO:0006119; GO:0070469,aerobic respiration; cytochrome-c oxidase activity; electron carrier activity; heme binding; integral to membrane; iron ion binding; mitochondrial inner membrane; oxidative phosphorylation; respiratory chain,PF00115;,2.00E-150,CHOYP_COX1.10.15,2.00E-34,ruditapes_c60,,,,,COX1_PARLI,Paracentrotus lividus (Common sea urchin),aerobic respiration [GO:0009060]; oxidative phosphorylation [GO:0006119] comp125992_c2_seq1,1087,44.2502,0.77197906,48,118,,4.00E-14,Q96K80,Zinc finger CCCH domain-containing protein 10,Zinc finger CCCH domain-containing protein 10,GO:0046872,metal ion binding,PF00642;,6.00E-20,CHOYP_ZC3HA.1.1,,,,,,,ZC3HA_HUMAN,Homo sapiens (Human), comp125997_c0_seq2,516,38.3721,0.84434328,0,18,,4.00E-30,P63331,Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16),Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16),GO:0000775; GO:0005829; GO:0007126; GO:0007498; GO:0046872; GO:0010719; GO:0005634; GO:0005886; GO:0071902; GO:0006470; GO:0046982; GO:0070208; GO:0000159; GO:0004722; GO:0031952; GO:0042176; GO:0010469; GO:0000922,"chromosome, centromeric region; cytosol; meiosis; mesoderm development; metal ion binding; negative regulation of epithelial to mesenchymal transition; nucleus; plasma membrane; positive regulation of protein serine/threonine kinase activity; protein dephosphorylation; protein heterodimerization activity; protein heterotrimerization; protein phosphatase type 2A complex; protein serine/threonine phosphatase activity; regulation of protein autophosphorylation; regulation of protein catabolic process; regulation of receptor activity; spindle pole",PF00149;,,,,,,,,,PP2AA_RAT,Rattus norvegicus (Rat),cardiac ventricle development [GO:0003231]; cellular response to calcium ion [GO:0071277]; cellular response to cytokine stimulus [GO:0071345]; cellular response to ethanol [GO:0071361]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to steroid hormone stimulus [GO:0071383]; heart development [GO:0007507]; meiotic cell cycle [GO:0051321]; negative regulation of calcium ion transmembrane transporter activity [GO:1901020]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphatase type 2A activity [GO:0034049]; protein dephosphorylation [GO:0006470]; protein heterotrimerization [GO:0070208]; regulation of protein autophosphorylation [GO:0031952]; regulation of protein catabolic process [GO:0042176]; regulation of protein phosphorylation [GO:0001932]; regulation of receptor activity [GO:0010469] comp125998_c0_seq3,329,34.0426,0.22059027,3,56,,,,,,,,,1.00E-14,CHOYP_LOC580832.1.1,,,,,,,,, comp126005_c0_seq1,224,31.25,0.18367713,3,15,,1.00E-07,Q0VCM2,Transmembrane protein 187,Transmembrane protein 187,GO:0016021; GO:0030133,integral to membrane; transport vesicle,PF15100;,3.00E-14,CHOYP_LOC100375233.1.1,,,,,,,TM187_BOVIN,Bos taurus (Bovine), comp126005_c1_seq2,696,43.6782,0.54767007,15,69,,2.00E-29,Q14656,Transmembrane protein 187 (Protein ITBA1),Transmembrane protein 187 (Protein ITBA1),GO:0016021; GO:0030133,integral to membrane; transport vesicle,PF15100;,,,,,,,,,TM187_HUMAN,Homo sapiens (Human), comp126008_c0_seq1,1678,41.4779,0.51304029,79,255,,5.00E-45,P20740,Ovostatin (Ovomacroglobulin),Ovostatin (Ovomacroglobulin),GO:0005615; GO:0010951; GO:0004867,extracellular space; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,OVOS_CHICK,Gallus gallus (Chicken), comp126009_c0_seq1,665,38.797,0.36582323,91,305,,2.00E-49,Q9BV90,U11/U12 small nuclear ribonucleoprotein 25 kDa protein (U11/U12 snRNP 25 kDa protein) (U11/U12-25K) (Minus-99 protein),U11/U12 small nuclear ribonucleoprotein 25 kDa protein (U11/U12 snRNP 25 kDa protein) (U11/U12-25K) (Minus-99 protein),GO:0008380; GO:0005689; GO:0006397,RNA splicing; U12-type spliceosomal complex; mRNA processing,,9.00E-34,CHOYP_LOC100701172.1.1,,,,,,,SNR25_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]" comp126010_c0_seq1,411,39.1727,0.32451358,15,48,,3.00E-28,Q96L50,Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5),Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5),GO:0016567,protein ubiquitination,PF12799;PF13516;,,,,,,,,,LLR1_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp126013_c2_seq1,766,46.4752,0.38881034,4,21,,2.00E-85,Q53FZ2,"Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Protein SA homolog)","Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Protein SA homolog)",GO:0005524; GO:0047760; GO:0042632; GO:0006633; GO:0015645; GO:0046872; GO:0005759; GO:0008217,ATP binding; butyrate-CoA ligase activity; cholesterol homeostasis; fatty acid biosynthetic process; fatty acid ligase activity; metal ion binding; mitochondrial matrix; regulation of blood pressure,PF00501;PF13193;,,,,,,,,,ACSM3_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; fatty acid biosynthetic process [GO:0006633]; regulation of blood pressure [GO:0008217] comp126013_c2_seq2,658,44.5289,0.40258552,0,0,,1.00E-06,Q9LQ12,4-coumarate--CoA ligase-like 1 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 10) (At4CL10),4-coumarate--CoA ligase-like 1 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 10) (At4CL10),GO:0005524; GO:0005737; GO:0046949; GO:0004467; GO:0031956; GO:0080110,ATP binding; cytoplasm; fatty-acyl-CoA biosynthetic process; long-chain fatty acid-CoA ligase activity; medium-chain fatty acid-CoA ligase activity; sporopollenin biosynthetic process,PF00501;PF13193;,2.00E-17,CHOYP_ACSM3.1.1,,,,,,,4CLL1_ARATH,Arabidopsis thaliana (Mouse-ear cress),fatty-acyl-CoA biosynthetic process [GO:0046949]; sporopollenin biosynthetic process [GO:0080110] comp126017_c0_seq1,370,45.6757,0.81028548,4,6,,8.00E-62,P31396,Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0000977; GO:0004879; GO:0007552; GO:0016319; GO:0000122; GO:0005634; GO:0045944; GO:0040034; GO:0003707; GO:0004887; GO:0008270,"RNA polymerase II regulatory region sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metamorphosis; mushroom body development; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of development, heterochronic; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,1.00E-41,CHOYP_LOC663422.1.1,,,,,,,HR3_DROME,Drosophila melanogaster (Fruit fly),"metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]" comp126017_c0_seq2,455,46.8132,0.70717364,21,45,,3.00E-47,P51448,Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1) (Retinoid-related orphan receptor-alpha),Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1) (RAR-related orphan receptor A) (Retinoid-related orphan receptor-alpha),GO:0003677; GO:0046068; GO:0021702; GO:0030522; GO:0004879; GO:0006809; GO:0005654; GO:0045944; GO:0043030; GO:0043565; GO:0003700; GO:0003707; GO:0008270,DNA binding; cGMP metabolic process; cerebellar Purkinje cell differentiation; intracellular receptor signaling pathway; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nitric oxide biosynthetic process; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; regulation of macrophage activation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,6.00E-15,CHOYP_E75BB.1.1,,,,,,,RORA_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to sterol [GO:0036315]; cellular response to tumor necrosis factor [GO:0071356]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; intracellular receptor signaling pathway [GO:0030522]; muscle cell differentiation [GO:0042692]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of cholesterol homeostasis [GO:2000188]; regulation of circadian rhythm [GO:0042752]; regulation of glucose metabolic process [GO:0010906]; regulation of macrophage activation [GO:0043030]; regulation of smoothened signaling pathway [GO:0008589]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]; xenobiotic metabolic process [GO:0006805]" comp126021_c0_seq1,1855,40.3235,0.5072681,8861,26806,,2.00E-80,P23004,"Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)","Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)",GO:0046872; GO:0004222; GO:0005743; GO:0055114; GO:0006508; GO:0070469,metal ion binding; metalloendopeptidase activity; mitochondrial inner membrane; oxidation-reduction process; proteolysis; respiratory chain,PF00675;PF05193;,,,,,,,,,QCR2_BOVIN,Bos taurus (Bovine),"aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; protein processing [GO:0016485]" comp126028_c0_seq1,1247,45.1484,0.55336004,0,0,,4.00E-06,Q01082,"Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)","Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)",GO:0043001; GO:0031430; GO:0007184; GO:0003779; GO:0051693; GO:0030506; GO:0030673; GO:0007411; GO:0007182; GO:0032437; GO:0005829; GO:0071709; GO:0000281; GO:0005730; GO:0005543; GO:0072661; GO:0008091; GO:0014731; GO:0005200,Golgi to plasma membrane protein transport; M band; SMAD protein import into nucleus; actin binding; actin filament capping; ankyrin binding; axolemma; axon guidance; common-partner SMAD protein phosphorylation; cuticular plate; cytosol; membrane assembly; mitotic cytokinesis; nucleolus; phospholipid binding; protein targeting to plasma membrane; spectrin; spectrin-associated cytoskeleton; structural constituent of cytoskeleton,PF00307;PF00435;,,,,,,,,,SPTB2_HUMAN,Homo sapiens (Human),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184] comp126028_c0_seq2,1367,44.989,0.49315095,5,3,,1.00E-82,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp126032_c0_seq1,543,42.3573,0.46517571,15,35,,,,,,,,,,,5.00E-21,ruditapes_c26495,,,,,,, comp126036_c0_seq1,2100,44,0.3841942,184,171,,1.00E-17,A8K0R7,Zinc finger protein 839 (Renal carcinoma antigen NY-REN-50),Zinc finger protein 839 (Renal carcinoma antigen NY-REN-50),GO:0046872,metal ion binding,PF15961;,2.00E-15,CHOYP_LOC100900174.1.1,,,,,,,ZN839_HUMAN,Homo sapiens (Human), comp126036_c2_seq1,303,36.9637,0,5,1,,,,,,,,,7.00E-12,CHOYP_LOC100900174.1.1,,,,,,,,, comp126039_c0_seq1,1100,37.6364,0.87610071,6,7,,7.00E-10,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126044_c1_seq1,864,49.0741,0.87639428,0,0,,5.00E-06,Q7SIG4,Diisopropyl-fluorophosphatase (DFPase) (EC 3.1.8.2),Diisopropyl-fluorophosphatase (DFPase) (EC 3.1.8.2),GO:0005509; GO:0047862,calcium ion binding; diisopropyl-fluorophosphatase activity,PF08450;,2.00E-19,CHOYP_RGN.1.1,2.00E-35,ruditapes2_c71,,,,,DFPA_LOLVU,Loligo vulgaris (Common European squid), comp126044_c1_seq2,1012,49.3083,0.90602424,6,41,,5.00E-82,Q5R837,Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30),Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30),GO:0005509; GO:0006874; GO:0005737; GO:0030234; GO:0004341; GO:0005634; GO:0032781; GO:0050848; GO:0008270,calcium ion binding; cellular calcium ion homeostasis; cytoplasm; enzyme regulator activity; gluconolactonase activity; nucleus; positive regulation of ATPase activity; regulation of calcium-mediated signaling; zinc ion binding,PF08450;,,,,,,,,,RGN_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular calcium ion homeostasis [GO:0006874]; positive regulation of ATPase activity [GO:0032781]; regulation of calcium-mediated signaling [GO:0050848] comp126045_c0_seq1,1754,47.7765,0.34459471,188,21,,0,Q5SPC5,Otoferlin (Fer-1-like protein 2),Otoferlin (Fer-1-like protein 2),GO:0016323; GO:0005509; GO:0030054; GO:0005789; GO:0016021; GO:0016079; GO:0030672,basolateral plasma membrane; calcium ion binding; cell junction; endoplasmic reticulum membrane; integral to membrane; synaptic vesicle exocytosis; synaptic vesicle membrane,PF00168;PF08150;PF08151;PF16165;,,,,,,,,,OTOF_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),neuromuscular process controlling balance [GO:0050885]; response to auditory stimulus [GO:0010996]; synaptic vesicle exocytosis [GO:0016079] comp126045_c2_seq2,887,45.3213,0.74955408,1,0,,3.00E-39,A6QQP7,Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1),Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1),GO:0030659; GO:0016021; GO:0042383; GO:0006906,cytoplasmic vesicle membrane; integral to membrane; sarcolemma; vesicle fusion,PF00168;PF08165;PF08150;PF08151;PF16165;,3.00E-117,CHOYP_OTOF.1.1,,,,,,,DYSF_BOVIN,Bos taurus (Bovine),vesicle fusion [GO:0006906] comp126045_c2_seq3,886,45.5982,0.76309612,0,0,,3.00E-32,B3DLH6,Myoferlin (Fer-1-like protein 3),Myoferlin (Fer-1-like protein 3),GO:0005901; GO:0030659; GO:0016021; GO:0031965; GO:0005543; GO:0001778,caveola; cytoplasmic vesicle membrane; integral to membrane; nuclear membrane; phospholipid binding; plasma membrane repair,PF00168;PF08165;PF08150;PF08151;PF16165;,,,,,,,,,MYOF_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778] comp126045_c2_seq5,956,45.1883,0.74001284,0,0,,1.00E-75,Q9ESF1,Otoferlin (Fer-1-like protein 2),Otoferlin (Fer-1-like protein 2),GO:0016323; GO:0005509; GO:0030054; GO:0005789; GO:0016021; GO:0007605; GO:0016079; GO:0030672,basolateral plasma membrane; calcium ion binding; cell junction; endoplasmic reticulum membrane; integral to membrane; sensory perception of sound; synaptic vesicle exocytosis; synaptic vesicle membrane,PF00168;PF08150;PF08151;PF16165;,,,,,,,,,OTOF_MOUSE,Mus musculus (Mouse),sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] comp126049_c0_seq1,806,38.4615,0.69794702,31,48,,9.00E-60,Q566C7,"Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3)","Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3)",GO:0005737; GO:0071544; GO:0008486; GO:0052840; GO:0052846; GO:0052847; GO:0052843; GO:0052848; GO:0052844; GO:0052845; GO:0000287,"cytoplasm; diphosphoinositol polyphosphate catabolic process; diphosphoinositol-polyphosphate diphosphatase activity; inositol diphosphate tetrakisphosphate diphosphatase activity; inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; magnesium ion binding",PF00293;,2.00E-31,CHOYP_LOC656747.1.1,,,,,,,NUDT3_RAT,Rattus norvegicus (Rat),diphosphoinositol polyphosphate catabolic process [GO:0071544] comp126057_c0_seq1,884,40.9502,0.79514927,3,160,,2.00E-14,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp126058_c0_seq1,676,41.716,0.30772795,6,0,,4.00E-52,Q9QY06,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0005524; GO:0005096; GO:0005100; GO:0007266; GO:0005938; GO:0030010; GO:0032433; GO:0035556; GO:0030027; GO:0072673; GO:0048246; GO:0046872; GO:0000146; GO:0002548; GO:0016459; GO:0048471; GO:0043547; GO:0001726,ATP binding; GTPase activator activity; Rho GTPase activator activity; Rho protein signal transduction; cell cortex; establishment of cell polarity; filopodium tip; intracellular signal transduction; lamellipodium; lamellipodium morphogenesis; macrophage chemotaxis; metal ion binding; microfilament motor activity; monocyte chemotaxis; myosin complex; perinuclear region of cytoplasm; positive regulation of GTPase activity; ruffle,PF00612;PF00063;PF00788;PF00620;,6.00E-55,CHOYP_LOC100870108.2.4,,,,,,,MYO9B_MOUSE,Mus musculus (Mouse),actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp126058_c0_seq2,926,46.1123,0.56968593,15,0,,2.00E-60,B2RTY4,Unconventional myosin-IXa (Unconventional myosin-9a),Unconventional myosin-IXa (Unconventional myosin-9a),GO:0005524; GO:0005096; GO:0005829; GO:0016021; GO:0046872; GO:0003774; GO:0043547; GO:0051056; GO:0007264; GO:0016461; GO:0007601,ATP binding; GTPase activator activity; cytosol; integral to membrane; metal ion binding; motor activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; unconventional myosin complex; visual perception,PF00612;PF00063;PF00788;PF00620;,7.00E-56,CHOYP_LOC100870108.4.4,,,,,,,MYO9A_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; regulation of small GTPase mediated signal transduction [GO:0051056]; visual perception [GO:0007601] comp126060_c0_seq1,524,43.8931,0.43670758,35,29,,5.00E-18,Q54BA2,"Ankyrin repeat, bromo and BTB domain-containing protein DDB_G0293800","Ankyrin repeat, bromo and BTB domain-containing protein DDB_G0293800",,,PF12796;PF17035;PF00439;PF00651;,7.00E-78,CHOYP_LOC100370913.1.1,,,,,,,Y3800_DICDI,Dictyostelium discoideum (Slime mold), comp126060_c1_seq1,683,48.7555,0.691909,0,0,,2.00E-13,Q755Y0,Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),GO:0000139; GO:0031901; GO:0016021; GO:0018345; GO:0006612; GO:0019706; GO:0030100; GO:0010969; GO:0008270,Golgi membrane; early endosome membrane; integral to membrane; protein palmitoylation; protein targeting to membrane; protein-cysteine S-palmitoyltransferase activity; regulation of endocytosis; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; zinc ion binding,PF12796;PF01529;,,,,,,,,,AKR1_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii), comp126060_c1_seq2,801,45.9426,0.73573742,0,0,,1.00E-12,A1ZBY1,Protein fem-1 homolog B (dFEM-1),Protein fem-1 homolog B (dFEM-1),GO:0051438; GO:0004842,regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,PF12796;,,,,,,,,,FEM1B_DROME,Drosophila melanogaster (Fruit fly),regulation of ubiquitin-protein transferase activity [GO:0051438] comp126060_c1_seq3,731,49.7948,0.6653953,7,4,,1.00E-85,Q5F478,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44),,,PF00023;PF12796;,1.00E-88,CHOYP_LOC100370913.1.1,,,,,,,ANR44_CHICK,Gallus gallus (Chicken), comp126060_c1_seq5,312,48.0769,0.6130761,2,0,,8.00E-06,O13987,Ankyrin and IPT/TIG repeat-containing protein C26H5.05,Ankyrin and IPT/TIG repeat-containing protein C26H5.05,GO:0000324; GO:0071458; GO:0036083; GO:0043234; GO:0005774,fungal-type vacuole; integral to cytosolic side of endoplasmic reticulum membrane; positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; protein complex; vacuolar membrane,PF12796;PF01833;,,,,,,,,,YEG5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [GO:0036083] comp126060_c1_seq6,264,45.0758,0.67411934,0,0,,3.00E-06,Q505D1,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK),GO:0005654,nucleoplasm,PF00023;PF12796;,,,,,,,,,ANR28_MOUSE,Mus musculus (Mouse), comp126066_c0_seq2,1047,42.6934,0.60976742,39,35,,3.00E-125,Q2TAF4,Integrator complex subunit 6-A (Int6-A),Integrator complex subunit 6-A (Int6-A),GO:0005634,nucleus,PF15300;PF13519;,9.00E-106,CHOYP_INT6.1.1,3.00E-14,ruditapes_c15353,,,,,INT6A_XENLA,Xenopus laevis (African clawed frog), comp126070_c0_seq2,463,40.6048,0.42129353,9,48,,6.00E-22,Q58CR4,Dolichol kinase (EC 2.7.1.108) (Transmembrane protein 15),Dolichol kinase (EC 2.7.1.108) (Transmembrane protein 15),GO:0004168; GO:0043048; GO:0030176,dolichol kinase activity; dolichyl monophosphate biosynthetic process; integral to endoplasmic reticulum membrane,,,,,,,,,,DOLK_BOVIN,Bos taurus (Bovine),dolichyl monophosphate biosynthetic process [GO:0043048] comp126074_c0_seq1,449,41.8708,0.93458408,2,27,,3.00E-22,Q498J9,Metallo-beta-lactamase domain-containing protein 1 (EC 3.-.-.-),Metallo-beta-lactamase domain-containing protein 1 (EC 3.-.-.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF00753;,2.00E-20,CHOYP_BRAFLDRAFT_241400.1.1,,,,,,,MBLC1_XENLA,Xenopus laevis (African clawed frog), comp126080_c0_seq2,981,46.789,0.62422533,16,11,,1.00E-69,O70566,Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3),Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3),GO:0003779; GO:0030041; GO:0030154; GO:0007275; GO:0048477,actin binding; actin filament polymerization; cell differentiation; multicellular organismal development; oogenesis,PF06345;PF06367;PF06371;PF02181;,2.00E-138,CHOYP_DIAP2.1.1,,,,,,,DIAP2_MOUSE,Mus musculus (Mouse),actin filament polymerization [GO:0030041]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477] comp126080_c0_seq4,599,47.0785,0.49987122,0,0,,2.00E-19,O70566,Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3),Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3),GO:0003779; GO:0030041; GO:0030154; GO:0007275; GO:0048477,actin binding; actin filament polymerization; cell differentiation; multicellular organismal development; oogenesis,PF06345;PF06367;PF06371;PF02181;,,,,,,,,,DIAP2_MOUSE,Mus musculus (Mouse),actin filament polymerization [GO:0030041]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477] comp126083_c0_seq1,1281,42.623,0.48374128,85,240,,7.00E-12,Q0VD59,E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII),E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII),GO:0002495; GO:0030659; GO:0031901; GO:0005768; GO:0016021; GO:0005765; GO:0005764; GO:0045347; GO:0000209; GO:0004842; GO:0008270,antigen processing and presentation of peptide antigen via MHC class II; cytoplasmic vesicle membrane; early endosome membrane; endosome; integral to membrane; lysosomal membrane; lysosome; negative regulation of MHC class II biosynthetic process; protein polyubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,2.00E-52,CHOYP_LOC594533.1.1,,,,,,,MARH8_BOVIN,Bos taurus (Bovine),adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209] comp126085_c0_seq1,843,38.6714,0.72508693,26,69,,3.00E-79,Q90ZK6,Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (Type I TGF B receptor),Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (Type I TGF B receptor),GO:0005524; GO:0030509; GO:0000082; GO:0048185; GO:0032924; GO:0002526; GO:0003289; GO:0060317; GO:0060923; GO:0016477; GO:0003143; GO:0061445; GO:0042118; GO:0005887; GO:0046872; GO:0003183; GO:0032926; GO:2001237; GO:0060389; GO:0018107; GO:0030513; GO:0010694; GO:0030501; GO:2000017; GO:0010718; GO:0045669; GO:0010862; GO:0045944; GO:0045893; GO:0005057; GO:0004702; GO:0023014; GO:0050431; GO:0005025,"ATP binding; BMP signaling pathway; G1/S transition of mitotic cell cycle; activin binding; activin receptor signaling pathway; acute inflammatory response; atrial septum primum morphogenesis; cardiac epithelial to mesenchymal transition; cardiac muscle cell fate commitment; cell migration; embryonic heart tube morphogenesis; endocardial cushion cell fate commitment; endothelial cell activation; integral to plasma membrane; metal ion binding; mitral valve morphogenesis; negative regulation of activin receptor signaling pathway; negative regulation of extrinsic apoptotic signaling pathway; pathway-restricted SMAD protein phosphorylation; peptidyl-threonine phosphorylation; positive regulation of BMP signaling pathway; positive regulation of alkaline phosphatase activity; positive regulation of bone mineralization; positive regulation of determination of dorsal identity; positive regulation of epithelial to mesenchymal transition; positive regulation of osteoblast differentiation; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; receptor signaling protein activity; receptor signaling protein serine/threonine kinase activity; signal transduction by phosphorylation; transforming growth factor beta binding; transforming growth factor beta receptor activity, type I",PF01064;PF07714;PF08515;,3.00E-48,CHOYP_ACVR1.2.2,,,,,,,ACVR1_CHICK,Gallus gallus (Chicken),"activin receptor signaling pathway [GO:0032924]; acute inflammatory response [GO:0002526]; atrial septum primum morphogenesis [GO:0003289]; BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell fate commitment [GO:0060923]; cell migration [GO:0016477]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion cell fate commitment [GO:0061445]; endothelial cell activation [GO:0042118]; G1/S transition of mitotic cell cycle [GO:0000082]; gastrulation with mouth forming second [GO:0001702]; germ cell development [GO:0007281]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; mesenchymal cell differentiation [GO:0048762]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neural crest cell migration [GO:0001755]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; patterning of blood vessels [GO:0001569]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of determination of dorsal identity [GO:2000017]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; smooth muscle cell differentiation [GO:0051145]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp126085_c1_seq1,513,47.7583,0.91371877,34,45,,3.00E-28,Q09488,Serine/threonine-protein kinase sma-6 (EC 2.7.11.30),Serine/threonine-protein kinase sma-6 (EC 2.7.11.30),GO:0005524; GO:0036122; GO:0030509; GO:0040024; GO:0050832; GO:0045087; GO:0016021; GO:0051457; GO:0005886; GO:0040018; GO:0045732; GO:0045944; GO:0004702; GO:0030155; GO:0000003; GO:0023014; GO:0045138; GO:0005024; GO:0004675,ATP binding; BMP binding; BMP signaling pathway; dauer larval development; defense response to fungus; innate immune response; integral to membrane; maintenance of protein location in nucleus; plasma membrane; positive regulation of multicellular organism growth; positive regulation of protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; receptor signaling protein serine/threonine kinase activity; regulation of cell adhesion; reproduction; signal transduction by phosphorylation; tail tip morphogenesis; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity,PF01064;PF00069;,,,,,,,,,SMA6_CAEEL,Caenorhabditis elegans,BMP signaling pathway [GO:0030509]; dauer larval development [GO:0040024]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; maintenance of protein location in nucleus [GO:0051457]; nematode male tail tip morphogenesis [GO:0045138]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell adhesion [GO:0030155]; regulation of cell morphogenesis [GO:0022604]; reproduction [GO:0000003] comp126087_c0_seq1,229,47.1616,1.10427346,20,24,,,,,,,,,,,6.00E-22,ruditapes_c27000,,,,,,, comp126096_c0_seq1,798,44.9875,0.55966721,30,46,,1.00E-54,Q68EM7,Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1),Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1),GO:0005096; GO:0005829; GO:0016020; GO:0043547; GO:0051056; GO:0007264; GO:0005923,GTPase activator activity; cytosol; membrane; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; tight junction,PF03114;PF00620;,,,,,,,,,RHG17_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp126096_c0_seq2,487,41.8891,0.47805844,0,3,,3.00E-28,Q68EM7,Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1),Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1),GO:0005096; GO:0005829; GO:0016020; GO:0043547; GO:0051056; GO:0007264; GO:0005923,GTPase activator activity; cytosol; membrane; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; tight junction,PF03114;PF00620;,,,,,,,,,RHG17_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp126097_c0_seq1,764,44.1099,0.43636438,0,0,,,,,,,,,1.00E-38,CHOYP_ENO.1.2,,,,,,,,, comp126097_c0_seq2,1386,45.0216,0.44582372,53,8,,2.00E-139,Q5ZK62,"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)","Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)",GO:0008060; GO:1990090; GO:0010008; GO:0005543; GO:0043547; GO:0036010; GO:0032312; GO:0008270,ARF GTPase activator activity; cellular response to nerve growth factor stimulus; endosome membrane; phospholipid binding; positive regulation of GTPase activity; protein localization to endosome; regulation of ARF GTPase activity; zinc ion binding,PF12796;PF01412;PF00169;,,,,,,,,,ACAP2_CHICK,Gallus gallus (Chicken),cellular response to nerve growth factor stimulus [GO:1990090]; protein localization to endosome [GO:0036010] comp126098_c0_seq2,959,42.1272,0.48344507,2,0,,,,,,,,,2.00E-44,CHOYP_BRAFLDRAFT_74381.1.1,,,,,,,,, comp126098_c0_seq3,671,41.8778,0.45124067,0,2,,4.00E-22,O35604,Niemann-Pick C1 protein,Niemann-Pick C1 protein,GO:0005794; GO:0007628; GO:0006914; GO:0008206; GO:0071404; GO:0071383; GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0006897; GO:0005783; GO:0005768; GO:0005576; GO:0008158; GO:0005887; GO:0031902; GO:0005765; GO:0007041; GO:0005764; GO:0045121; GO:0016242; GO:0005635; GO:0048471; GO:0006486; GO:0042493; GO:0031982,Golgi apparatus; adult walking behavior; autophagy; bile acid metabolic process; cellular response to low-density lipoprotein particle stimulus; cellular response to steroid hormone stimulus; cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; endocytosis; endoplasmic reticulum; endosome; extracellular region; hedgehog receptor activity; integral to plasma membrane; late endosome membrane; lysosomal membrane; lysosomal transport; lysosome; membrane raft; negative regulation of macroautophagy; nuclear envelope; perinuclear region of cytoplasm; protein glycosylation; response to drug; vesicle,PF16414;PF02460;PF12349;,1.00E-44,CHOYP_BRAFLDRAFT_74381.1.1,,,,,,,NPC1_MOUSE,Mus musculus (Mouse),adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; lysosomal transport [GO:0007041]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; positive regulation of cholesterol homeostasis [GO:2000189]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; viral entry into host cell [GO:0046718] comp126103_c0_seq1,892,35.8744,0.51595129,4856,17689,,7.00E-06,Q8SPH5,"Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein)","Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein)",GO:0006122; GO:0005743; GO:0070469; GO:0008121,"mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial inner membrane; respiratory chain; ubiquinol-cytochrome-c reductase activity",PF02320;,,,,,,,,,QCR6_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp126109_c0_seq1,1113,39.982,0.40850785,390,1315,,7.00E-14,A6QPQ5,"39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1)","39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1)",GO:0003723; GO:0015934; GO:0005739; GO:0003735; GO:0006412,RNA binding; large ribosomal subunit; mitochondrion; structural constituent of ribosome; translation,PF00687;,,,1.00E-12,ruditapes_c25975,,,,,RM01_BOVIN,Bos taurus (Bovine),maturation of LSU-rRNA [GO:0000470]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; translation [GO:0006412] comp126110_c0_seq1,977,43.8076,0.45131566,61,24,,6.00E-34,Q5SPL2,PHD finger protein 12 (PHD factor 1) (Pf1),PHD finger protein 12 (PHD factor 1) (Pf1),GO:0001106; GO:0016580; GO:0035091; GO:0017053; GO:0008270,RNA polymerase II transcription corepressor activity; Sin3 complex; phosphatidylinositol binding; transcriptional repressor complex; zinc ion binding,PF00628;PF16737;,1.00E-34,CHOYP_BRAFLDRAFT_89536.1.1,,,,,,,PHF12_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp126110_c1_seq1,209,41.6268,0.67309233,5,0,,6.00E-09,Q96QT6,PHD finger protein 12 (PHD factor 1) (Pf1),PHD finger protein 12 (PHD factor 1) (Pf1),GO:0001106; GO:0016580; GO:0035091; GO:0017053; GO:0008270,RNA polymerase II transcription corepressor activity; Sin3 complex; phosphatidylinositol binding; transcriptional repressor complex; zinc ion binding,PF00628;PF16737;,,,,,,,,,PHF12_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp126113_c2_seq1,551,40.4719,0.58858462,62,51,,9.00E-08,Q62313,Trans-Golgi network integral membrane protein 1 (TGN38A),Trans-Golgi network integral membrane protein 1 (TGN38A),GO:0005794; GO:0016021; GO:0005886; GO:0005802,Golgi apparatus; integral to membrane; plasma membrane; trans-Golgi network,,,,,,,,,,TGON1_MOUSE,Mus musculus (Mouse),Golgi to endosome transport [GO:0006895] comp126122_c0_seq1,1173,41.006,0.75596992,25,243,,7.00E-13,O62515,Probable phytanoyl-CoA dioxygenase (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH),Probable phytanoyl-CoA dioxygenase (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH),GO:0031418; GO:0006631; GO:0046872; GO:0048244,L-ascorbic acid binding; fatty acid metabolic process; metal ion binding; phytanoyl-CoA dioxygenase activity,PF05721;,1.00E-23,CHOYP_BRAFLDRAFT_84643.1.1,3.00E-21,ruditapes_c26815,,,,,PAHX_CAEEL,Caenorhabditis elegans,fatty acid alpha-oxidation [GO:0001561] comp126124_c0_seq1,1439,38.5685,0.37952683,14,14,,7.00E-86,P50904,Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),GO:0005099; GO:0030036; GO:0007155; GO:0000910; GO:0005737; GO:0009790; GO:0031235; GO:0046580; GO:0001953; GO:0043524; GO:0005543; GO:0030833; GO:0007165; GO:0001570,Ras GTPase activator activity; actin cytoskeleton organization; cell adhesion; cytokinesis; cytoplasm; embryo development; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; negative regulation of cell-matrix adhesion; negative regulation of neuron apoptotic process; phospholipid binding; regulation of actin filament polymerization; signal transduction; vasculogenesis,PF00168;PF00169;PF00616;PF00017;PF00018;,,,,,,,,,RASA1_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; embryo development [GO:0009790]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to drug [GO:0042493]; response to insulin [GO:0032868]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] comp126124_c0_seq2,1495,38.0602,0.37485296,2,2,,1.00E-85,P50904,Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),GO:0005099; GO:0030036; GO:0007155; GO:0000910; GO:0005737; GO:0009790; GO:0031235; GO:0046580; GO:0001953; GO:0043524; GO:0005543; GO:0030833; GO:0007165; GO:0001570,Ras GTPase activator activity; actin cytoskeleton organization; cell adhesion; cytokinesis; cytoplasm; embryo development; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; negative regulation of cell-matrix adhesion; negative regulation of neuron apoptotic process; phospholipid binding; regulation of actin filament polymerization; signal transduction; vasculogenesis,PF00168;PF00169;PF00616;PF00017;PF00018;,,,,,,,,,RASA1_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; embryo development [GO:0009790]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to drug [GO:0042493]; response to insulin [GO:0032868]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] comp126125_c0_seq1,1905,33.5433,0.69948442,1960,320,,7.00E-09,Q9UL19,Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein),Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein),GO:0016021; GO:0016042; GO:0008285; GO:0004623; GO:0006644,integral to membrane; lipid catabolic process; negative regulation of cell proliferation; phospholipase A2 activity; phospholipid metabolic process,PF04970;,,,,,,,,,TIG3_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; negative regulation of cell proliferation [GO:0008285]; phospholipid metabolic process [GO:0006644] comp126129_c0_seq1,1125,35.0222,0.49611277,559,6637,,6.00E-50,Q4KLF8,Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC),Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC),GO:0005737; GO:0005856; GO:0030027; GO:0030833,cytoplasm; cytoskeleton; lamellipodium; regulation of actin filament polymerization,PF04699;,1.00E-21,CHOYP_FYN.1.1,7.00E-74,ruditapes_c29798,,,,,ARPC5_RAT,Rattus norvegicus (Rat),actin filament network formation [GO:0051639]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; lamellipodium organization [GO:0097581]; maintenance of cell polarity [GO:0030011]; microtubule organizing center organization [GO:0031023]; orbitofrontal cortex development [GO:0021769]; smooth muscle cell migration [GO:0014909] comp126137_c0_seq1,3775,45.5099,0.96258487,2530,25517,,0,O96064,Paramyosin,Paramyosin,GO:0003774; GO:0030016; GO:0032982,motor activity; myofibril; myosin filament,PF01576;,0,CHOYP_MYSP.5.9,7.00E-86,ruditapes_c13063,,,,,MYSP_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp126138_c0_seq1,822,37.8345,0.55622284,44,204,,1.00E-68,Q5D013,Methyltransferase-like protein 10 (EC 2.1.1.-),Protein-lysine N-methyltransferase mettl10 (EC 2.1.1.-) (Methyltransferase-like protein 10),GO:0008168,methyltransferase activity,PF13847;,,,2.00E-98,ruditapes_c15021,,,,,MET10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126138_c0_seq2,815,38.773,0.60110588,0,22,,1.00E-46,Q5JPI9,Methyltransferase-like protein 10 (EC 2.1.1.-),Protein-lysine N-methyltransferase METTL10 (EC 2.1.1.-) (Methyltransferase-like protein 10),GO:0008168,methyltransferase activity,PF13847;,7.00E-30,CHOYP_RAB7A.1.2,,,,,,,MET10_HUMAN,Homo sapiens (Human), comp126141_c1_seq1,1014,37.7712,0.58371729,39,49,,2.00E-15,Q9H9H4,Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B),Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B),GO:0000813; GO:0016197; GO:0031902; GO:0030496; GO:0015031; GO:0019082; GO:0019068,ESCRT I complex; endosomal transport; late endosome membrane; midbody; protein transport; viral protein processing; virion assembly,PF07200;,,,,,,,,,VP37B_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; endosomal transport [GO:0016197]; intracellular transport of virus [GO:0075733]; multivesicular body assembly [GO:0036258]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein transport [GO:0015031]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058] comp126143_c0_seq1,930,42.2581,0.41107003,59,16,,3.00E-101,Q803C9,Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I),Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I),GO:0005789; GO:0016021; GO:0006659; GO:0016740,endoplasmic reticulum membrane; integral to membrane; phosphatidylserine biosynthetic process; transferase activity,PF03034;,1.00E-91,CHOYP_PTDSS1.1.1,,,,,,,PTSS1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654] comp126144_c1_seq1,224,45.0893,0.99240149,8,0,,1.00E-08,O77621,Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Fragment),Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Fragment),GO:0071875; GO:0007512; GO:0004937; GO:0016049; GO:0016021; GO:0001985; GO:0001994; GO:0031965; GO:0035265; GO:0007200; GO:0097195; GO:0005886; GO:0043410; GO:0001996; GO:0045987; GO:0001997; GO:0046982; GO:0055117; GO:0019229,adrenergic receptor signaling pathway; adult heart development; alpha1-adrenergic receptor activity; cell growth; integral to membrane; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; nuclear membrane; organ growth; phospholipase C-activating G-protein coupled receptor signaling pathway; pilomotor reflex; plasma membrane; positive regulation of MAPK cascade; positive regulation of heart rate by epinephrine-norepinephrine; positive regulation of smooth muscle contraction; positive regulation of the force of heart contraction by epinephrine-norepinephrine; protein heterodimerization activity; regulation of cardiac muscle contraction; regulation of vasoconstriction,PF00001;,5.00E-12,CHOYP_5-HTAP1.1.1,,,,,,,ADA1A_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] comp126144_c2_seq1,1077,35.8403,0.9490228,46,51,,6.00E-25,P28285,5-hydroxytryptamine receptor 2A (5-HT receptor 2A) (Serotonin receptor 2A),5-hydroxytryptamine receptor 2A (5-HT receptor 2A) (Serotonin receptor 2A),GO:0001586; GO:0007198; GO:0007615; GO:0016021; GO:0007208; GO:0005886; GO:0045187,"Gi/o-coupled serotonin receptor activity; adenylate cyclase-inhibiting serotonin receptor signaling pathway; anesthesia-resistant memory; integral to membrane; phospholipase C-activating serotonin receptor signaling pathway; plasma membrane; regulation of circadian sleep/wake cycle, sleep",PF00001;,,,,,,,,,5HT2A_DROME,Drosophila melanogaster (Fruit fly),"adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; anesthesia-resistant memory [GO:0007615]; inter-male aggressive behavior [GO:0002121]; male courtship behavior [GO:0008049]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin receptor signaling pathway [GO:0007210]" comp126145_c0_seq4,796,41.4573,0.3002001,3,20,,2.00E-38,Q7TPS5,C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein),C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein),GO:0005509; GO:0005544; GO:0005938; GO:0030659; GO:0038028; GO:0065002; GO:2001275; GO:0090314; GO:0031340; GO:0072659; GO:0032587; GO:0006906,calcium ion binding; calcium-dependent phospholipid binding; cell cortex; cytoplasmic vesicle membrane; insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; intracellular protein transmembrane transport; positive regulation of glucose import in response to insulin stimulus; positive regulation of protein targeting to membrane; positive regulation of vesicle fusion; protein localization to plasma membrane; ruffle membrane; vesicle fusion,PF00168;,6.00E-31,CHOYP_LOC100865656.1.1,,,,,,,K0528_MOUSE,Mus musculus (Mouse),cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; membrane organization [GO:0061024]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of glucose transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659]; vesicle fusion [GO:0006906] comp126146_c0_seq1,712,43.3989,0.86623547,239,1068,,1.00E-20,P47967,Galectin-5 (Gal-5) (RL-18),Galectin-5 (Gal-5) (RL-18),GO:0030246,carbohydrate binding,PF00337;,,,,,,,,,LEG5_RAT,Rattus norvegicus (Rat), comp126150_c0_seq1,548,43.0657,0.46159292,47,156,,2.00E-23,Q5ZMU6,Serine/threonine-protein phosphatase 4 regulatory subunit 2,Serine/threonine-protein phosphatase 4 regulatory subunit 2,GO:0005634; GO:0030289; GO:0030362; GO:0010569,nucleus; protein phosphatase 4 complex; protein phosphatase type 4 regulator activity; regulation of double-strand break repair via homologous recombination,PF09184;,5.00E-11,CHOYP_LOC578003.1.1,,,,,,,PP4R2_CHICK,Gallus gallus (Chicken), comp126151_c0_seq1,1145,43.5808,0.46818351,0,0,,7.00E-73,O35551,Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha),Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha),GO:0005096; GO:0006915; GO:0005769; GO:0030139; GO:0006897; GO:0005768; GO:0043547; GO:0015031; GO:0055037,GTPase activator activity; apoptotic process; early endosome; endocytic vesicle; endocytosis; endosome; positive regulation of GTPase activity; protein transport; recycling endosome,PF09311;PF03528;,,,,,,,,,RABE1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp126151_c0_seq2,2107,40.5316,0.49439368,44,59,,9.00E-15,Q15075,Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2),Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2),GO:0005545; GO:0030742; GO:0005516; GO:0005829; GO:0005769; GO:0031901; GO:0045022; GO:0019897; GO:0042803; GO:0055037; GO:0005969; GO:0016189; GO:0006906; GO:0008270,1-phosphatidylinositol binding; GTP-dependent protein binding; calmodulin binding; cytosol; early endosome; early endosome membrane; early endosome to late endosome transport; extrinsic to plasma membrane; protein homodimerization activity; recycling endosome; serine-pyruvate aminotransferase complex; synaptic vesicle to endosome fusion; vesicle fusion; zinc ion binding,PF01363;,4.00E-114,CHOYP_LOC585032.2.2,,,,,,,EEA1_HUMAN,Homo sapiens (Human),early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] comp126154_c0_seq1,815,32.3926,0.5175583,35,311,,,,,,,,,,,4.00E-11,ruditapes_lrc23864,,,,,,, comp126159_c0_seq1,1084,30.0738,0.49122849,33,195,,3.00E-11,Q9NV72,Zinc finger protein 701,Zinc finger protein 701,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN701_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126166_c0_seq1,1249,40.9127,0.48180728,35,151,,4.00E-167,P36898,Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (Activin receptor-like kinase 6) (ALK-6) (Serine/threonine-protein kinase receptor R6) (SKR6) (CD antigen CDw293),Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (Activin receptor-like kinase 6) (ALK-6) (Serine/threonine-protein kinase receptor R6) (SKR6) (CD antigen CDw293),GO:0005524; GO:0030509; GO:0001502; GO:0002062; GO:0009953; GO:0006703; GO:0006954; GO:0016021; GO:0035108; GO:0046872; GO:0001550; GO:0030501; GO:1902043; GO:0045669; GO:0060041; GO:0031290; GO:0005025; GO:0007179,"ATP binding; BMP signaling pathway; cartilage condensation; chondrocyte differentiation; dorsal/ventral pattern formation; estrogen biosynthetic process; inflammatory response; integral to membrane; limb morphogenesis; metal ion binding; ovarian cumulus expansion; positive regulation of bone mineralization; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of osteoblast differentiation; retina development in camera-type eye; retinal ganglion cell axon guidance; transforming growth factor beta receptor activity, type I; transforming growth factor beta receptor signaling pathway",PF01064;PF07714;PF08515;,2.00E-65,CHOYP_BMR1A.1.1,,,,,,,BMR1B_MOUSE,Mus musculus (Mouse),BMP signaling pathway [GO:0030509]; camera-type eye development [GO:0043010]; cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte development [GO:0002063]; chondrocyte differentiation [GO:0002062]; dorsal/ventral pattern formation [GO:0009953]; endochondral bone morphogenesis [GO:0060350]; estrogen biosynthetic process [GO:0006703]; eye development [GO:0001654]; inflammatory response [GO:0006954]; limb morphogenesis [GO:0035108]; negative regulation of chondrocyte proliferation [GO:1902731]; ovarian cumulus expansion [GO:0001550]; ovulation cycle [GO:0042698]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; retina development in camera-type eye [GO:0060041]; retinal ganglion cell axon guidance [GO:0031290]; skeletal system development [GO:0001501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] comp126167_c0_seq3,649,40.832,0.59859702,0,0,,6.00E-48,Q6AYQ1,Golgin subfamily A member 7,Golgin subfamily A member 7,GO:0000139,Golgi membrane,PF10256;,3.00E-21,CHOYP_LOC656123.1.1,,,,,,,GOGA7_RAT,Rattus norvegicus (Rat),Golgi to plasma membrane protein transport [GO:0043001]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein stabilization [GO:0050821]; protein targeting to membrane [GO:0006612] comp126168_c0_seq1,618,39.9676,1.21994801,1,15,,7.00E-30,P36633,Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase),Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase),GO:0009308; GO:0005261; GO:0097185; GO:0071280; GO:0035874; GO:0071420; GO:0005507; GO:0052597; GO:0008144; GO:0005615; GO:0008201; GO:0052598; GO:0052599; GO:0005886; GO:0008131; GO:0052600; GO:0032403; GO:0048038; GO:0004872; GO:0046677; GO:0042493; GO:0005923; GO:0008270,"amine metabolic process; cation channel activity; cellular response to azide; cellular response to copper ion; cellular response to copper ion starvation; cellular response to histamine; copper ion binding; diamine oxidase activity; drug binding; extracellular space; heparin binding; histamine oxidase activity; methylputrescine oxidase activity; plasma membrane; primary amine oxidase activity; propane-1,3-diamine oxidase activity; protein complex binding; quinone binding; receptor activity; response to antibiotic; response to drug; tight junction; zinc ion binding",PF01179;PF02727;PF02728;,3.00E-21,CHOYP_BRAFLDRAFT_217424.1.2,,,,,,,ABP1_RAT,Rattus norvegicus (Rat),amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; response to drug [GO:0042493] comp126168_c0_seq2,522,37.7395,1.46910652,3,60,,4.00E-12,P80695,Primary amine oxidase (EC 1.4.3.21) (Monamine oxidase) (Tyramine oxidase),Primary amine oxidase (EC 1.4.3.21) (Monamine oxidase) (Tyramine oxidase),GO:0052595; GO:0009308; GO:0052594; GO:0006584; GO:0005507; GO:0042597; GO:0052596; GO:0008131; GO:0048038; GO:0052593,aliphatic-amine oxidase activity; amine metabolic process; aminoacetone:oxygen oxidoreductase(deaminating) activity; catecholamine metabolic process; copper ion binding; periplasmic space; phenethylamine:oxygen oxidoreductase (deaminating) activity; primary amine oxidase activity; quinone binding; tryptamine:oxygen oxidoreductase (deaminating) activity,PF01179;PF07833;PF02727;PF02728;,,,,,,,,,AMO_KLEOK,Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686),amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584] comp126187_c0_seq1,1480,34.4595,0.6039576,4,3,,6.00E-15,A0JNH9,Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF),Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF),GO:0008408; GO:0003906; GO:0005829; GO:0006302; GO:0004520; GO:0046872; GO:0000166; GO:0005634; GO:0000012,3'-5' exonuclease activity; DNA-(apurinic or apyrimidinic site) lyase activity; cytosol; double-strand break repair; endodeoxyribonuclease activity; metal ion binding; nucleotide binding; nucleus; single strand break repair,PF10283;,,,,,,,,,APLF_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012] comp126187_c0_seq3,1342,35.3949,0.61692795,0,0,,5.00E-15,A0JNH9,Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF),Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF),GO:0008408; GO:0003906; GO:0005829; GO:0006302; GO:0004520; GO:0046872; GO:0000166; GO:0005634; GO:0000012,3'-5' exonuclease activity; DNA-(apurinic or apyrimidinic site) lyase activity; cytosol; double-strand break repair; endodeoxyribonuclease activity; metal ion binding; nucleotide binding; nucleus; single strand break repair,PF10283;,,,,,,,,,APLF_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012] comp126189_c0_seq1,1223,37.8577,0.48926483,155,91,,4.00E-14,Q8NEP7,Kelch domain-containing protein 9 (Kelch/ankyrin repeat-containing cyclin A1-interacting protein),Kelch domain-containing protein 9 (Kelch/ankyrin repeat-containing cyclin A1-interacting protein),,,,,,,,,,,,KLDC9_HUMAN,Homo sapiens (Human), comp126191_c0_seq2,868,43.0876,1.22454366,0,0,,1.00E-14,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp126192_c0_seq1,1104,47.2826,0.9280933,0,0,,9.00E-30,Q66PY1,"Signal peptide, CUB and EGF-like domain-containing protein 3","Signal peptide, CUB and EGF-like domain-containing protein 3",GO:0005509; GO:0009986; GO:0005576; GO:0051291; GO:0051260,calcium ion binding; cell surface; extracellular region; protein heterooligomerization; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB3_MOUSE,Mus musculus (Mouse),protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] comp126192_c0_seq2,867,45.4441,0.94230895,0,0,,1.00E-29,Q5G872,"Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein You)","Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein You)",GO:0008015; GO:0005509; GO:0009897; GO:0005615; GO:0042694; GO:0048747; GO:0007517; GO:0030514; GO:0030141; GO:0007224; GO:0001756,blood circulation; calcium ion binding; external side of plasma membrane; extracellular space; muscle cell fate specification; muscle fiber development; muscle organ development; negative regulation of BMP signaling pathway; secretory granule; smoothened signaling pathway; somitogenesis,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),blood circulation [GO:0008015]; muscle cell fate specification [GO:0042694]; muscle fiber development [GO:0048747]; muscle organ development [GO:0007517]; smoothened signaling pathway [GO:0007224]; somitogenesis [GO:0001756]; striated muscle cell differentiation [GO:0051146] comp126192_c0_seq3,1567,47.4154,0.99860955,6,2,,2.00E-105,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp126192_c0_seq4,1495,47.0234,0.99145847,0,0,,3.00E-93,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp126199_c0_seq1,1337,36.5744,0.66471411,6137,25008,,7.00E-141,P61258,Proliferating cell nuclear antigen (PCNA),Proliferating cell nuclear antigen (PCNA),GO:0003677; GO:0030337; GO:0006260; GO:0043626; GO:0070557; GO:0032077; GO:0006275; GO:0019985,DNA binding; DNA polymerase processivity factor activity; DNA replication; PCNA complex; PCNA-p21 complex; positive regulation of deoxyribonuclease activity; regulation of DNA replication; translesion synthesis,PF02747;PF00705;,1.00E-143,CHOYP_ISCW_ISCW022029.1.1,1.00E-179,ruditapes_c7097,,,,,PCNA_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),DNA replication [GO:0006260]; positive regulation of deoxyribonuclease activity [GO:0032077]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985] comp126201_c1_seq1,1205,40.9129,0.46000032,60,57,,1.00E-39,Q9NQG5,Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor),Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor),GO:0016591; GO:0000993; GO:0070940; GO:0008284; GO:0045944; GO:0010564; GO:0006351,"DNA-directed RNA polymerase II, holoenzyme; RNA polymerase II core binding; dephosphorylation of RNA polymerase II C-terminal domain; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle process; transcription, DNA-dependent",PF16566;PF04818;,,,,,,,,,RPR1B_HUMAN,Homo sapiens (Human),dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle process [GO:0010564]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp126203_c0_seq1,438,45.6621,0.61962214,19,42,,1.00E-29,P10688,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)",GO:0005509; GO:0005829; GO:0051482; GO:0035556; GO:0016042; GO:0045121; GO:0031966; GO:0005634; GO:0004435; GO:0005546; GO:0032962; GO:0010701; GO:1900274; GO:0010044; GO:0051592; GO:0055093; GO:0043434; GO:0034696; GO:0004871,"calcium ion binding; cytosol; elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; intracellular signal transduction; lipid catabolic process; membrane raft; mitochondrial membrane; nucleus; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; positive regulation of inositol trisphosphate biosynthetic process; positive regulation of norepinephrine secretion; regulation of phospholipase C activity; response to aluminum ion; response to calcium ion; response to hyperoxia; response to peptide hormone stimulus; response to prostaglandin F stimulus; signal transducer activity",PF00168;PF09279;PF16457;PF00388;PF00387;,,,,,,,,,PLCD1_RAT,Rattus norvegicus (Rat),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696] comp126203_c1_seq1,282,44.6809,0.35796048,10,3,,,,,,,,,,,9.00E-21,ruditapes2_c2698,,,,,,, comp126203_c2_seq1,470,45.9574,0.49688137,23,47,,1.00E-32,P10895,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)",GO:0001525; GO:0005509; GO:0005829; GO:0035556; GO:0060716; GO:0016042; GO:0004435; GO:0005543; GO:0042127; GO:0004871,angiogenesis; calcium ion binding; cytosol; intracellular signal transduction; labyrinthine layer blood vessel development; lipid catabolic process; phosphatidylinositol phospholipase C activity; phospholipid binding; regulation of cell proliferation; signal transducer activity,PF00168;PF09279;PF00169;PF00388;PF00387;,8.00E-20,CHOYP_PLCD1.1.1,,,,,,,PLCD1_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipid catabolic process [GO:0016042]; regulation of cell proliferation [GO:0042127] comp126204_c0_seq1,559,47.4061,0.44687786,0,5,,5.00E-30,Q91ZU6,Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0016023; GO:0031122; GO:0005789; GO:0005925; GO:0030056; GO:0016021; GO:0014704; GO:0005882; GO:0045104; GO:0009898; GO:0046907; GO:0015630; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0097038; GO:0042803; GO:0031110; GO:0008090; GO:0042383; GO:0001725,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; endoplasmic reticulum membrane; focal adhesion; hemidesmosome; integral to membrane; intercalated disc; intermediate filament; intermediate filament cytoskeleton organization; internal side of plasma membrane; intracellular transport; microtubule cytoskeleton; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; retrograde axon cargo transport; sarcolemma; stress fiber,PF00307;PF13499;PF02187;PF00681;PF00435;,,,,,,,,,DYST_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090] comp126204_c0_seq2,670,48.3582,0.46108139,4,14,,8.00E-07,Q9QWN8,"Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)","Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)",GO:0051693; GO:0005829; GO:0016363; GO:0005543; GO:0017158; GO:0008091; GO:0005200; GO:0016081,actin filament capping; cytosol; nuclear matrix; phospholipid binding; regulation of calcium ion-dependent exocytosis; spectrin; structural constituent of cytoskeleton; synaptic vesicle docking involved in exocytosis,PF00307;PF00435;,7.00E-92,CHOYP_LOC100647948.1.1,,,,,,,SPTN2_RAT,Rattus norvegicus (Rat),actin filament capping [GO:0051693]; cellular response to ethanol [GO:0071361]; regulation of calcium ion-dependent exocytosis [GO:0017158]; synaptic vesicle docking [GO:0016081]; synaptic vesicle exocytosis [GO:0016079] comp126204_c4_seq1,542,39.1144,1.05070017,11,67,,1.00E-48,Q9UPN3,"Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)","Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)",GO:0016887; GO:0005794; GO:0043001; GO:0016055; GO:0015629; GO:0051015; GO:0005509; GO:0007050; GO:0006928; GO:0007163; GO:0001707; GO:0005874; GO:0008017; GO:0030177; GO:0006620; GO:0010632; GO:0051893; GO:0032886; GO:0032587; GO:0042060,ATPase activity; Golgi apparatus; Golgi to plasma membrane protein transport; Wnt receptor signaling pathway; actin cytoskeleton; actin filament binding; calcium ion binding; cell cycle arrest; cellular component movement; establishment or maintenance of cell polarity; mesoderm formation; microtubule; microtubule binding; positive regulation of Wnt receptor signaling pathway; posttranslational protein targeting to membrane; regulation of epithelial cell migration; regulation of focal adhesion assembly; regulation of microtubule-based process; ruffle membrane; wound healing,PF00307;PF13499;PF02187;PF00681;PF00435;,8.00E-59,CHOYP_BRAFLDRAFT_123699.1.1,,,,,,,MACF1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] comp126221_c0_seq1,443,28.8939,0.32551486,7,67,,,,,,,,,,,2.00E-11,ruditapes_c5350,,,,,,, comp126240_c0_seq1,680,46.3235,1.0690761,10,32,,3.00E-47,Q9UBQ7,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0034641; GO:0007588; GO:0008465; GO:0046487; GO:0030267; GO:0016618; GO:0005782; GO:0042803; GO:0051259,NAD binding; NADPH binding; cellular nitrogen compound metabolic process; excretion; glycerate dehydrogenase activity; glyoxylate metabolic process; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; peroxisomal matrix; protein homodimerization activity; protein oligomerization,PF00389;PF02826;,,,,,,,,,GRHPR_HUMAN,Homo sapiens (Human),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp126243_c0_seq1,1237,38.1568,0.74556586,6192,14531,,1.00E-98,Q69BJ7,"Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 11 (Complex III subunit IX) (Ubiquinol-cytochrome c reductase 8 kDa protein)]","Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 11 (Complex III subunit IX) (Ubiquinol-cytochrome c reductase 8 kDa protein)]",GO:0051537; GO:0016021; GO:0046872; GO:0005743; GO:0070469; GO:0008121,"2 iron, 2 sulfur cluster binding; integral to membrane; metal ion binding; mitochondrial inner membrane; respiratory chain; ubiquinol-cytochrome-c reductase activity",PF00355;PF09165;PF02921;,,,6.00E-62,ruditapes2_c1692,,,,,UCRI_SAISC,Saimiri sciureus (Common squirrel monkey), comp126251_c1_seq1,254,51.1811,0.54526861,3,14,,,,,,,,,2.00E-44,CHOYP_LOC580791.1.1,,,,,,,,, comp126251_c2_seq1,289,41.5225,0.40379208,0,9,,4.00E-40,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,,,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp126253_c1_seq2,872,38.5321,0.836208,13,28,,7.00E-49,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp126253_c1_seq3,1432,38.8268,0.8176364,0,2,,9.00E-40,Q9JI67,"Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (Stage-specific embryonic antigen 3 synthase) (SSEA-3 synthase) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5)","Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (Stage-specific embryonic antigen 3 synthase) (SSEA-3 synthase) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5)",GO:0000139; GO:0005783; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; endoplasmic reticulum; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT5_MOUSE,Mus musculus (Mouse),protein glycosylation [GO:0006486] comp126254_c0_seq1,1032,37.2093,0.5884768,2,0,,3.00E-66,Q9VZV5,Cysteine and histidine-rich protein 1 homolog,Cysteine and histidine-rich protein 1 homolog,GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,CYHR1_DROME,Drosophila melanogaster (Fruit fly), comp126254_c0_seq3,1558,39.8588,0.63101714,17,0,,2.00E-132,Q2TAD9,Cysteine and histidine-rich protein 1-B,Cysteine and histidine-rich protein 1-B,GO:0005737; GO:0008270,cytoplasm; zinc ion binding,,9.00E-64,CHOYP_LOC100372774.1.2,,,,,,,CYR1B_XENLA,Xenopus laevis (African clawed frog), comp126255_c0_seq1,499,38.8778,0.31898055,0,0,,4.00E-11,Q9NPA5,"Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)","Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)",GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZF64A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126257_c2_seq1,2104,44.3441,0.34323005,68,120,,1.00E-119,Q6GNT7,Golgin subfamily A member 5 (Golgin-84),Golgin subfamily A member 5 (Golgin-84),GO:0005794; GO:0000139; GO:0007030; GO:0048193; GO:0016021; GO:0042803,Golgi apparatus; Golgi membrane; Golgi organization; Golgi vesicle transport; integral to membrane; protein homodimerization activity,PF09787;,8.00E-123,CHOYP_BRAFLDRAFT_154839.1.1,,,,,,,GOGA5_XENLA,Xenopus laevis (African clawed frog),Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193] comp126262_c0_seq2,1248,47.5962,0.47546404,9,42,,,,,,,,,1.00E-17,CHOYP_PHUM_PHUM549810.1.1,,,,,,,,, comp126264_c0_seq1,614,44.7883,1.17143168,0,121,,2.00E-30,P21589,5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73),5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73),GO:0008253; GO:0006196; GO:0006259; GO:0046086; GO:0031225; GO:0005737; GO:0070062; GO:0046872; GO:0050728; GO:0000166; GO:0005886; GO:0006144; GO:0006195; GO:0006206; GO:0046135,5'-nucleotidase activity; AMP catabolic process; DNA metabolic process; adenosine biosynthetic process; anchored to membrane; cytoplasm; extracellular vesicular exosome; metal ion binding; negative regulation of inflammatory response; nucleotide binding; plasma membrane; purine nucleobase metabolic process; purine nucleotide catabolic process; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process,PF02872;PF00149;,,,,,,,,,5NTD_HUMAN,Homo sapiens (Human),adenosine biosynthetic process [GO:0046086]; AMP catabolic process [GO:0006196]; brain development [GO:0007420]; DNA metabolic process [GO:0006259]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of inflammatory response [GO:0050728]; positive regulation of lipid biosynthetic process [GO:0046889]; purine nucleotide biosynthetic process [GO:0006164]; purine nucleotide catabolic process [GO:0006195]; pyrimidine nucleoside catabolic process [GO:0046135]; response to aluminum ion [GO:0010044] comp126265_c0_seq1,982,38.5947,0.44424405,650,1388,,2.00E-82,O75431,Metaxin-2 (Mitochondrial outer membrane import complex protein 2),Metaxin-2 (Mitochondrial outer membrane import complex protein 2),GO:0044267; GO:0005741; GO:0006626,cellular protein metabolic process; mitochondrial outer membrane; protein targeting to mitochondrion,PF17171;PF10568;,2.00E-18,CHOYP_LOC663155.1.1,2.00E-155,ruditapes2_c645,,,,,MTX2_HUMAN,Homo sapiens (Human),mitochondrial transport [GO:0006839]; protein targeting to mitochondrion [GO:0006626] comp126269_c0_seq1,1168,44.863,0.41414768,44,90,,1.00E-16,A9CPT4,Tudor domain-containing protein 1,Tudor domain-containing protein 1,GO:0043046; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_ORYLA,Oryzias latipes (Japanese rice fish) (Japanese killifish),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp126270_c0_seq3,896,45.7589,0.46962292,5,27,,6.00E-127,P48506,Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase),Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase),GO:0043531; GO:0005524; GO:0019852; GO:0045454; GO:0050662; GO:0006534; GO:0005829; GO:0016595; GO:0006536; GO:0004357; GO:0017109; GO:0006750; GO:1901687; GO:0000287; GO:0043066; GO:0043524; GO:0031397; GO:0045892; GO:0032436; GO:0050880; GO:0051900; GO:0046685; GO:0009408; GO:0009725; GO:0051409; GO:0006979; GO:0006805,"ADP binding; ATP binding; L-ascorbic acid metabolic process; cell redox homeostasis; coenzyme binding; cysteine metabolic process; cytosol; glutamate binding; glutamate metabolic process; glutamate-cysteine ligase activity; glutamate-cysteine ligase complex; glutathione biosynthetic process; glutathione derivative biosynthetic process; magnesium ion binding; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; negative regulation of protein ubiquitination; negative regulation of transcription, DNA-dependent; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of blood vessel size; regulation of mitochondrial depolarization; response to arsenic-containing substance; response to heat; response to hormone stimulus; response to nitrosative stress; response to oxidative stress; xenobiotic metabolic process",PF03074;,3.00E-79,CHOYP_GSH1.1.1,,,,,,,GSH1_HUMAN,Homo sapiens (Human),"apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to arsenic-containing substance [GO:0046685]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; sulfur amino acid metabolic process [GO:0000096]" comp126275_c0_seq1,913,41.9496,0.39622035,51,71,,3.00E-23,Q9NW13,RNA-binding protein 28 (RNA-binding motif protein 28),RNA-binding protein 28 (RNA-binding motif protein 28),GO:0005794; GO:0003723; GO:0008380; GO:0006397; GO:0005730; GO:0000166; GO:0005681,Golgi apparatus; RNA binding; RNA splicing; mRNA processing; nucleolus; nucleotide binding; spliceosomal complex,PF00076;,,,,,,,,,RBM28_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp126284_c0_seq2,1115,42.0628,0.28631139,21,142,,4.00E-105,Q6DGA6,Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase),Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase),GO:0004037; GO:0000256; GO:0006144,allantoicase activity; allantoin catabolic process; purine nucleobase metabolic process,PF03561;,7.00E-57,CHOYP_NEMVEDRAFT_V1G235970.1.1,,,,,,,ALLC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] comp126294_c0_seq1,714,48.4594,0.57404856,31,21,,1.00E-40,A2A9C3,Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,3.00E-15,CHOYP_SZT2.1.1,,,,,,,SZT2_MOUSE,Mus musculus (Mouse),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp126298_c1_seq1,501,44.9102,0.5959188,15,6,,1.00E-14,Q8K4S1,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)",GO:0000139; GO:0000187; GO:0005509; GO:0005829; GO:0019899; GO:0032835; GO:0005085; GO:0016042; GO:0004435; GO:0007200; GO:0005886; GO:0008277; GO:0046578; GO:0004871; GO:0007264,Golgi membrane; activation of MAPK activity; calcium ion binding; cytosol; enzyme binding; glomerulus development; guanyl-nucleotide exchange factor activity; lipid catabolic process; phosphatidylinositol phospholipase C activity; phospholipase C-activating G-protein coupled receptor signaling pathway; plasma membrane; regulation of G-protein coupled receptor protein signaling pathway; regulation of Ras protein signal transduction; signal transducer activity; small GTPase mediated signal transduction,PF00168;PF00388;PF00387;PF00788;PF00617;,9.00E-26,CHOYP_FUCTA.2.4,,,,,,,PLCE1_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; glomerulus development [GO:0032835]; lipid catabolic process [GO:0016042]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; Ras protein signal transduction [GO:0007265]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of protein kinase activity [GO:0045859]; regulation of Ras protein signal transduction [GO:0046578] comp126299_c0_seq1,1130,41.7699,1.51356455,75,95,,2.00E-52,Q2PYN8,Transcription factor LBX1 (Ladybird homeobox protein homolog 1),Transcription factor LBX1 (Ladybird homeobox protein homolog 1),GO:0030154; GO:0007517; GO:0051450; GO:0000122; GO:0005634; GO:0003700; GO:0005667; GO:0000976; GO:0006351,"cell differentiation; muscle organ development; myoblast proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00046;,4.00E-54,CHOYP_LBX1.1.1,,,,,,,LBX1_XENLA,Xenopus laevis (African clawed frog),"cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126310_c0_seq1,871,39.4948,0.27304075,14,115,,3.00E-12,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp126311_c3_seq2,968,42.8719,0.56539761,2,44,,3.00E-29,O08734,Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK),Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK),GO:0001783; GO:0001782; GO:0002352; GO:0008635; GO:1902262; GO:0001974; GO:0008283; GO:0034644; GO:0005829; GO:0005783; GO:0010248; GO:0097192; GO:0044346; GO:0031307; GO:0008630; GO:0070059; GO:0035108; GO:0046872; GO:0008053; GO:0002262; GO:0033137; GO:0046930; GO:0043065; GO:0010524; GO:0048597; GO:0032471; GO:0051726; GO:0046902; GO:0051881; GO:0001836; GO:0009620; GO:0010332; GO:0010046; GO:0070242; GO:0060068,B cell apoptotic process; B cell homeostasis; B cell negative selection; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; apoptotic process involved in patterning of blood vessels; blood vessel remodeling; cell proliferation; cellular response to UV; cytosol; endoplasmic reticulum; establishment or maintenance of transmembrane electrochemical gradient; extrinsic apoptotic signaling pathway in absence of ligand; fibroblast apoptotic process; integral to mitochondrial outer membrane; intrinsic apoptotic signaling pathway in response to DNA damage; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; limb morphogenesis; metal ion binding; mitochondrial fusion; myeloid cell homeostasis; negative regulation of peptidyl-serine phosphorylation; pore complex; positive regulation of apoptotic process; positive regulation of calcium ion transport into cytosol; post-embryonic camera-type eye morphogenesis; reduction of endoplasmic reticulum calcium ion concentration; regulation of cell cycle; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; release of cytochrome c from mitochondria; response to fungus; response to gamma radiation; response to mycotoxin; thymocyte apoptotic process; vagina development,PF00452;,,,,,,,,,BAK_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; apoptotic process involved in patterning of blood vessels [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell negative selection [GO:0002352]; blood vessel remodeling [GO:0001974]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cellular response to UV [GO:0034644]; cytolysis [GO:0019835]; endocrine pancreas development [GO:0031018]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fibroblast apoptotic process [GO:0044346]; homeostasis of number of cells [GO:0048872]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte homeostasis [GO:0001776]; limb morphogenesis [GO:0035108]; mitochondrial fusion [GO:0008053]; myeloid cell homeostasis [GO:0002262]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; post-embryonic camera-type eye morphogenesis [GO:0048597]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; release of cytochrome c from mitochondria [GO:0001836]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungus [GO:0009620]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to mycotoxin [GO:0010046]; response to organic cyclic compound [GO:0014070]; response to UV-C [GO:0010225]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068] comp126311_c3_seq3,994,42.9577,0.54899636,4,0,,1.00E-31,Q16611,Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7),Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7),GO:0001783; GO:0001782; GO:0002352; GO:0097202; GO:0008635; GO:0007568; GO:0001974; GO:0007420; GO:0008283; GO:0034644; GO:0071260; GO:0005829; GO:0031018; GO:0005783; GO:0010248; GO:0031307; GO:0097193; GO:0070059; GO:0035108; GO:0046872; GO:0008053; GO:0002262; GO:0008285; GO:0010629; GO:0033137; GO:0031100; GO:0046930; GO:0043065; GO:0010524; GO:1900103; GO:1901030; GO:0045862; GO:0090200; GO:0048597; GO:0032471; GO:0051726; GO:0046902; GO:0051881; GO:0043497; GO:0043496; GO:0001836; GO:0010225; GO:0042493; GO:0045471; GO:0009620; GO:0010332; GO:0042542; GO:0010046; GO:0014070; GO:0060068,B cell apoptotic process; B cell homeostasis; B cell negative selection; activation of cysteine-type endopeptidase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; aging; blood vessel remodeling; brain development; cell proliferation; cellular response to UV; cellular response to mechanical stimulus; cytosol; endocrine pancreas development; endoplasmic reticulum; establishment or maintenance of transmembrane electrochemical gradient; integral to mitochondrial outer membrane; intrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; limb morphogenesis; metal ion binding; mitochondrial fusion; myeloid cell homeostasis; negative regulation of cell proliferation; negative regulation of gene expression; negative regulation of peptidyl-serine phosphorylation; organ regeneration; pore complex; positive regulation of apoptotic process; positive regulation of calcium ion transport into cytosol; positive regulation of endoplasmic reticulum unfolded protein response; positive regulation of mitochondrial outer membrane permeabilization; positive regulation of proteolysis; positive regulation of release of cytochrome c from mitochondria; post-embryonic camera-type eye morphogenesis; reduction of endoplasmic reticulum calcium ion concentration; regulation of cell cycle; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; regulation of protein heterodimerization activity; regulation of protein homodimerization activity; release of cytochrome c from mitochondria; response to UV-C; response to drug; response to ethanol; response to fungus; response to gamma radiation; response to hydrogen peroxide; response to mycotoxin; response to organic cyclic compound; vagina development,PF00452;,,,,,,,,,BAK_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; activation of signaling protein activity involved in unfolded protein response [GO:0006987]; aging [GO:0007568]; apoptotic process involved in patterning of blood vessels [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell negative selection [GO:0002352]; blood vessel remodeling [GO:0001974]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cellular response to UV [GO:0034644]; cytolysis [GO:0019835]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fibroblast apoptotic process [GO:0044346]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; limb morphogenesis [GO:0035108]; mitochondrial fusion [GO:0008053]; myeloid cell homeostasis [GO:0002262]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; post-embryonic camera-type eye morphogenesis [GO:0048597]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; release of cytochrome c from mitochondria [GO:0001836]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungus [GO:0009620]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to mycotoxin [GO:0010046]; response to organic cyclic compound [GO:0014070]; response to UV-C [GO:0010225]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068] comp126315_c0_seq2,1208,37.6656,0.98121806,31,189,,2.00E-60,Q6UXT9,Abhydrolase domain-containing protein 15 (EC 3.1.1.-),Protein ABHD15 (EC 3.1.1.-) (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15),GO:0004091; GO:0005576,carboxylesterase activity; extracellular region,PF12146;,5.00E-21,CHOYP_LOC100497109.1.1,,,,,,,ABH15_HUMAN,Homo sapiens (Human), comp126324_c0_seq1,623,41.4125,0.45326993,0,4,,5.00E-26,Q9W0Y2,Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-),Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-),GO:0016746,"transferase activity, transferring acyl groups",PF06094;,,,,,,,,,YS11_DROME,Drosophila melanogaster (Fruit fly), comp126324_c0_seq2,995,39.8995,0.3049605,0,0,,4.00E-25,Q9W0Y2,Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-),Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-),GO:0016746,"transferase activity, transferring acyl groups",PF06094;,,,,,,,,,YS11_DROME,Drosophila melanogaster (Fruit fly), comp126334_c1_seq1,1522,46.7148,0.47039697,63,21,,6.00E-72,Q92508,Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A),Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A),GO:0005261; GO:0050982; GO:0005783; GO:0005789; GO:0033116; GO:0016021; GO:0008381; GO:0005886; GO:0033634; GO:0033625; GO:0042391,cation channel activity; detection of mechanical stimulus; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; mechanically-gated ion channel activity; plasma membrane; positive regulation of cell-cell adhesion mediated by integrin; positive regulation of integrin activation; regulation of membrane potential,PF15917;PF12166;,3.00E-38,CHOYP_LOC100747115.1.1,,,,,,,PIEZ1_HUMAN,Homo sapiens (Human),cation transport [GO:0006812]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of integrin activation [GO:0033625] comp126334_c1_seq2,646,43.9628,0.35302664,0,0,,,,,,,,,1.00E-38,CHOYP_LOC100877728.1.1,,,,,,,,, comp126335_c0_seq1,1655,42.4169,0.29136132,69,91,,1.00E-143,O94966,Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9),Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9),GO:0030433; GO:0005829; GO:0005789; GO:0016021; GO:0046872; GO:0048642; GO:0090068; GO:0016579; GO:1900037; GO:0031647; GO:0034976; GO:0014732; GO:0004221; GO:0004843,ER-associated protein catabolic process; cytosol; endoplasmic reticulum membrane; integral to membrane; metal ion binding; negative regulation of skeletal muscle tissue development; positive regulation of cell cycle process; protein deubiquitination; regulation of cellular response to hypoxia; regulation of protein stability; response to endoplasmic reticulum stress; skeletal muscle atrophy; ubiquitin thiolesterase activity; ubiquitin-specific protease activity,PF04969;PF00443;PF01753;,3.00E-114,CHOYP_UBP19.1.1,,,,,,,UBP19_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976] comp126345_c0_seq1,383,44.9086,0.80672819,0,0,,2.00E-07,Q9ZW21,Probable protein phosphatase 2C 24 (AtPP2C24) (EC 3.1.3.16),Probable protein phosphatase 2C 24 (AtPP2C24) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C24_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp126345_c0_seq2,845,43.432,0.5532519,11,36,,5.00E-80,Q641Y6,Protein phosphatase 1J (EC 3.1.3.16) (Protein phosphatase 2C isoform zeta) (PP2C-zeta),Protein phosphatase 1J (EC 3.1.3.16) (Protein phosphatase 2C isoform zeta) (PP2C-zeta),GO:0006470; GO:0004722,protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,6.00E-12,CHOYP_PPM1H.1.1,,,,,,,PPM1J_RAT,Rattus norvegicus (Rat), comp12634_c0_seq1,241,67.6349,0.94978087,0,4,,4.00E-08,P13511,Cobalt-zinc-cadmium resistance protein CzcA (Cation efflux system protein CzcA),Cobalt-zinc-cadmium resistance protein CzcA (Cation efflux system protein CzcA),GO:0008324; GO:0016021; GO:0005886; GO:0046686,cation transmembrane transporter activity; integral to membrane; plasma membrane; response to cadmium ion,PF00873;,,,,,,,,,CZCA_RALME,Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans),response to cadmium ion [GO:0046686] comp126359_c0_seq2,1218,44.0887,0.42284133,24,55,,1.00E-167,Q9UKZ1,CCR4-NOT transcription complex subunit 11,CCR4-NOT transcription complex subunit 11,GO:0030014; GO:0008283; GO:0005829; GO:0031047; GO:0000289; GO:0005634; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; cell proliferation; cytosol; gene silencing by RNA; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF10155;,0,CHOYP_LOC100367053.1.1,,,,,,,CB029_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]" comp126359_c0_seq3,764,46.3351,0.31769157,2,0,,6.00E-90,Q9UKZ1,CCR4-NOT transcription complex subunit 11,CCR4-NOT transcription complex subunit 11,GO:0030014; GO:0008283; GO:0005829; GO:0031047; GO:0000289; GO:0005634; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; cell proliferation; cytosol; gene silencing by RNA; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF10155;,,,,,,,,,CB029_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]" comp126362_c0_seq2,1506,42.4303,0.3587385,36,51,,9.00E-133,Q9JJK2,LanC-like protein 2 (Testis-specific adriamycin sensitivity protein),LanC-like protein 2 (Testis-specific adriamycin sensitivity protein),GO:0003824; GO:0030864; GO:0005829; GO:0008152; GO:0045892; GO:0005634; GO:0032266; GO:0070273; GO:0010314; GO:0005886; GO:0009789,"catalytic activity; cortical actin cytoskeleton; cytosol; metabolic process; negative regulation of transcription, DNA-dependent; nucleus; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; plasma membrane; positive regulation of abscisic acid mediated signaling pathway",PF05147;,,,,,,,,,LANC2_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]" comp126363_c0_seq1,654,42.3547,1.00449732,36,193,,4.00E-50,Q7PCJ8,Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2),Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2),GO:0005737; GO:0004145; GO:0009447,cytoplasm; diamine N-acetyltransferase activity; putrescine catabolic process,PF00583;,,,,,,,,,SAT2_BOVIN,Bos taurus (Bovine),nor-spermidine metabolic process [GO:0046204]; putrescine acetylation [GO:0032920]; putrescine catabolic process [GO:0009447]; spermidine acetylation [GO:0032918]; spermine acetylation [GO:0032919] comp126374_c0_seq1,2970,41.7508,0.84456468,1534,4,male>female,1.00E-15,Q9H0A9,Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein),Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein),,,PF15059;PF15058;,,,,,,,,,CU056_HUMAN,Homo sapiens (Human), comp126375_c0_seq1,1474,37.6526,0.82958418,2998,1,male>female,3.00E-73,Q96PF2,Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B),Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B),GO:0005524; GO:0001669; GO:0005814; GO:0005737; GO:0000287; GO:0007275; GO:0046777; GO:0004674; GO:0007286,ATP binding; acrosomal vesicle; centriole; cytoplasm; magnesium ion binding; multicellular organismal development; protein autophosphorylation; protein serine/threonine kinase activity; spermatid development,PF00069;,3.00E-95,CHOYP_LOC100370380.1.1,,,,,,,TSSK2_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] comp126380_c1_seq6,2138,41.8148,0.33903087,0,0,,2.00E-09,O15050,TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),GO:0005524; GO:0016787,ATP binding; hydrolase activity,PF00580;,,,,,,,,,TRNK1_HUMAN,Homo sapiens (Human), comp126385_c0_seq1,682,37.6833,0.46462685,0,0,,2.00E-31,P18729,Gastrula zinc finger protein XlCGF57.1 (Fragment),Gastrula zinc finger protein XlCGF57.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG57_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126385_c0_seq2,1105,36.1991,0.33843357,9,87,,2.00E-27,Q6NX49,Zinc finger protein 544,Zinc finger protein 544,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN544_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126385_c2_seq1,716,35.7542,0.52837244,7,76,,9.00E-21,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp126386_c1_seq1,1561,41.7681,0.25563428,83,146,,2.00E-108,Q8BXN9,Transmembrane protein 87A,Transmembrane protein 87A,GO:0016021,integral to membrane,PF06814;,2.00E-96,CHOYP_LOC100706133.1.1,,,,,,,TM87A_MOUSE,Mus musculus (Mouse), comp126387_c1_seq1,441,38.0952,0.71500368,5,72,,5.00E-12,Q62210,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Inhibitor of apoptosis protein 2) (IAP-2) (mIAP-2) (mIAP2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2),GO:0035631; GO:0006915; GO:0005737; GO:0009898; GO:0070266; GO:0060546; GO:1902443; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0070936; GO:0070534; GO:0042981; GO:0051726; GO:2000377; GO:0006355; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; apoptotic process; cytoplasm; internal side of plasma membrane; necroptosis; negative regulation of necroptosis; negative regulation of ripoptosome assembly involved in necroptosis; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein K63-linked ubiquitination; regulation of apoptotic process; regulation of cell cycle; regulation of reactive oxygen species metabolic process; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_MOUSE,Mus musculus (Mouse),"inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp126399_c0_seq1,506,41.502,1.05769121,14,0,,2.00E-22,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,3.00E-11,ruditapes_c21092,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp126399_c0_seq2,368,41.0326,1.23130519,0,11,,2.00E-10,P11368,Putative Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)],Putative Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0075713; GO:0090305; GO:0004523; GO:0046718; GO:0008270,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; viral entry into host cell; zinc ion binding,PF00552;PF02022;PF00075;PF00665;PF00078;PF06817;,,,,,,,,,POL_IPMA,Mouse intracisternal a-particle MIA14 (IAP-MIA14),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp126415_c0_seq1,1655,36.9184,0.58006801,347,2041,,5.00E-25,Q7TNV0,Protein DEK,Protein DEK,GO:0003677; GO:0016568; GO:0005634; GO:2001032,DNA binding; chromatin modification; nucleus; regulation of double-strand break repair via nonhomologous end joining,PF08766;,,,,,,,,,DEK_MOUSE,Mus musculus (Mouse),chromatin modification [GO:0016568]; regulation of double-strand break repair [GO:2000779]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032] comp126422_c0_seq1,838,36.5155,0.72577958,0,108,,2.00E-22,Q96LR7,Uncharacterized protein C2orf50,Uncharacterized protein C2orf50,,,,2.00E-17,CHOYP_contig_056432,,,,,,,CB050_HUMAN,Homo sapiens (Human), comp126425_c1_seq1,530,37.7358,0.80300719,19,18,,4.00E-65,O19175,Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) (Fragment),Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) (Fragment),GO:0005524; GO:0016055; GO:0051301; GO:0000902; GO:0000777; GO:0005737; GO:0005815; GO:0007067; GO:0016607; GO:0004674; GO:0030529,ATP binding; Wnt receptor signaling pathway; cell division; cell morphogenesis; condensed chromosome kinetochore; cytoplasm; microtubule organizing center; mitosis; nuclear speck; protein serine/threonine kinase activity; ribonucleoprotein complex,PF00069;,,,,,,,,,KC1A_PIG,Sus scrofa (Pig),cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055] comp126425_c2_seq1,1301,37.2022,0.49726606,69,171,,9.00E-104,Q8BK63,Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1),Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1),GO:0005524; GO:0016055; GO:0051301; GO:0000902; GO:0000777; GO:0005737; GO:0005815; GO:0007067; GO:0016607; GO:0004674; GO:0030529,ATP binding; Wnt receptor signaling pathway; cell division; cell morphogenesis; condensed chromosome kinetochore; cytoplasm; microtubule organizing center; mitosis; nuclear speck; protein serine/threonine kinase activity; ribonucleoprotein complex,PF00069;,2.00E-122,CHOYP_KC1A.2.2,7.00E-157,ruditapes_c16356,,,,,KC1A_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cell morphogenesis [GO:0000902]; Golgi organization [GO:0007030]; intermediate filament cytoskeleton organization [GO:0045104]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of GTP binding [GO:1904424]; Wnt signaling pathway [GO:0016055] comp126429_c0_seq1,1010,41.1881,0.76158267,0,0,,2.00E-33,Q9BX51,Gamma-glutamyltransferase light chain 1 (Gamma-glutamyltransferase-like activity 4) (Gamma-glutamyltransferase-like protein 6),Gamma-glutamyltransferase light chain 1 (Gamma-glutamyltransferase-like activity 4) (Gamma-glutamyltransferase-like protein 6),GO:0031362; GO:0003840; GO:0006749; GO:0019370,anchored to external side of plasma membrane; gamma-glutamyltransferase activity; glutathione metabolic process; leukotriene biosynthetic process,PF01019;,,,,,,,,,GGTL1_HUMAN,Homo sapiens (Human),glutathione metabolic process [GO:0006749]; leukotriene biosynthetic process [GO:0019370] comp126429_c0_seq2,1108,41.9675,0.69226024,3,16,,6.00E-63,P07314,Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain],Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain],GO:0007568; GO:0034599; GO:0005615; GO:0003840; GO:0006536; GO:0006750; GO:0006751; GO:0036374; GO:0005887; GO:0031179; GO:0032355; GO:0032496; GO:0034612,aging; cellular response to oxidative stress; extracellular space; gamma-glutamyltransferase activity; glutamate metabolic process; glutathione biosynthetic process; glutathione catabolic process; glutathione hydrolase activity; integral to plasma membrane; peptide modification; response to estradiol stimulus; response to lipopolysaccharide; response to tumor necrosis factor,PF01019;,,,,,,,,,GGT1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; peptide modification [GO:0031179]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; zymogen activation [GO:0031638] comp126430_c1_seq1,403,44.4169,0.61212498,9,42,,5.00E-69,Q13042,Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6),Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6),GO:0005680; GO:0031145; GO:0051301; GO:0008283; GO:0005813; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979; GO:0005876,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cell proliferation; centrosome; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; spindle microtubule,,6.00E-59,CHOYP_LOC101158148.1.1,,,,,,,CDC16_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of mitotic nuclear division [GO:0007088]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp126431_c2_seq2,1180,45.7627,0.68455314,0,0,,5.00E-20,Q14995,Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R),Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb alpha-related receptor) (RVR) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R),GO:0004879; GO:0005654; GO:0043565; GO:0003707; GO:0006367; GO:0008270,ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleoplasm; sequence-specific DNA binding; steroid hormone receptor activity; transcription initiation from RNA polymerase II promoter; zinc ion binding,PF00104;PF00105;,6.00E-83,CHOYP_NR5A2.1.1,,,,,,,NR1D2_HUMAN,Homo sapiens (Human),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp126431_c2_seq4,1565,43.7061,0.68649406,28,29,,5.00E-59,P33244,Nuclear hormone receptor FTZ-F1 (FTZ-F1 alpha) (Nuclear receptor subfamily 5 group A member 3),Nuclear hormone receptor FTZ-F1 (FTZ-F1 alpha) (Nuclear receptor subfamily 5 group A member 3),GO:0001077; GO:0008219; GO:0005737; GO:0007480; GO:0035626; GO:0004879; GO:0055088; GO:0016319; GO:0005634; GO:0042048; GO:0007365; GO:0035073; GO:0035074; GO:0040034; GO:0035075; GO:0003707; GO:0000976; GO:0008270,"RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell death; cytoplasm; imaginal disc-derived leg morphogenesis; juvenile hormone mediated signaling pathway; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; lipid homeostasis; mushroom body development; nucleus; olfactory behavior; periodic partitioning; pupariation; pupation; regulation of development, heterochronic; response to ecdysone; steroid hormone receptor activity; transcription regulatory region sequence-specific DNA binding; zinc ion binding",PF00104;PF00105;,1.00E-81,CHOYP_FTZ-F1.1.1,,,,,,,FTZF1_DROME,Drosophila melanogaster (Fruit fly),"cell death [GO:0008219]; dendrite morphogenesis [GO:0048813]; imaginal disc-derived leg morphogenesis [GO:0007480]; instar larval or pupal development [GO:0002165]; juvenile hormone mediated signaling pathway [GO:0035626]; lipid homeostasis [GO:0055088]; metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; neuron remodeling [GO:0016322]; olfactory behavior [GO:0042048]; periodic partitioning [GO:0007365]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pupariation [GO:0035073]; pupation [GO:0035074]; regulation of development, heterochronic [GO:0040034]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ecdysone [GO:0035075]; response to hormone [GO:0009725]; salivary gland cell autophagic cell death [GO:0035071]" comp126436_c0_seq1,933,41.0504,0.28309302,33,114,,6.00E-24,Q14146,Unhealthy ribosome biogenesis protein 2 homolog,Unhealthy ribosome biogenesis protein 2 homolog,GO:0005730,nucleolus,PF10441;,,,,,,,,,URB2_HUMAN,Homo sapiens (Human), comp126437_c0_seq3,1207,38.691,0.56169365,33,124,,5.00E-16,Q9R1W3,E3 ubiquitin-protein ligase RNF103 (EC 6.3.2.-) (KF-1) (mKF-1) (RING finger protein 103) (Zinc finger protein 103) (Zfp-103),E3 ubiquitin-protein ligase RNF103 (EC 6.3.2.-) (KF-1) (mKF-1) (RING finger protein 103) (Zinc finger protein 103) (Zfp-103),GO:0030433; GO:0005783; GO:0005789; GO:0016021; GO:0004842; GO:0008270,ER-associated protein catabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,RN103_MOUSE,Mus musculus (Mouse),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567] comp126452_c0_seq1,1147,40.8021,0.56732907,0,0,,7.00E-52,Q6P0D7,MAGUK p55 subfamily member 7 (Protein humpback),MAGUK p55 subfamily member 7 (Protein humpback),GO:0005912; GO:0016020; GO:0005923,adherens junction; membrane; tight junction,PF00625;PF02828;PF00595;PF07653;,,,,,,,,,MPP7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126452_c0_seq2,1828,39.6608,0.36994348,0,0,,2.00E-80,Q8BVD5,MAGUK p55 subfamily member 7,MAGUK p55 subfamily member 7,GO:0097025; GO:0031334; GO:0032947; GO:0019904; GO:0046982; GO:0071896; GO:0005923; GO:0070830,MPP7-DLG1-LIN7 complex; positive regulation of protein complex assembly; protein complex scaffold; protein domain specific binding; protein heterodimerization activity; protein localization to adherens junction; tight junction; tight junction assembly,PF00625;PF02828;PF00595;PF07653;,9.00E-71,CHOYP_MPP2.1.1,6.00E-109,ruditapes_c17359,,,,,MPP7_MOUSE,Mus musculus (Mouse),bicellular tight junction assembly [GO:0070830]; positive regulation of protein complex assembly [GO:0031334]; protein localization to adherens junction [GO:0071896] comp126452_c0_seq3,2500,40.72,0.4803734,0,0,,1.00E-150,Q9WV34,MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2),MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2),,,PF00625;PF02828;PF00595;PF07653;,,,3.00E-19,ruditapes_c26857,,,,,MPP2_MOUSE,Mus musculus (Mouse), comp126452_c0_seq4,475,36.8421,0.24875992,0,0,,4.00E-43,Q14168,MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2),MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2),GO:0009986; GO:0004385; GO:0005887; GO:0007165,cell surface; guanylate kinase activity; integral to plasma membrane; signal transduction,PF00625;PF02828;PF00595;PF07653;,,,1.00E-14,ruditapes_c7268,,,,,MPP2_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp126458_c0_seq1,660,44.8485,0.42441851,0,0,,4.00E-74,O08575,Eyes absent homolog 2 (EC 3.1.3.48),Eyes absent homolog 2 (EC 3.1.3.48),GO:0006281; GO:0005737; GO:0097192; GO:0016576; GO:0000287; GO:0097345; GO:0005739; GO:0007275; GO:0005634; GO:0004725; GO:0006355; GO:0014706; GO:0006351,"DNA repair; cytoplasm; extrinsic apoptotic signaling pathway in absence of ligand; histone dephosphorylation; magnesium ion binding; mitochondrial outer membrane permeabilization; mitochondrion; multicellular organismal development; nucleus; protein tyrosine phosphatase activity; regulation of transcription, DNA-dependent; striated muscle tissue development; transcription, DNA-dependent",,,,,,,,,,EYA2_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; histone dephosphorylation [GO:0016576]; mitochondrial outer membrane permeabilization [GO:0097345]; multicellular organism development [GO:0007275]; protein dephosphorylation [GO:0006470]; regulation of transcription, DNA-templated [GO:0006355]; striated muscle tissue development [GO:0014706]; transcription, DNA-templated [GO:0006351]" comp126458_c0_seq2,606,44.3894,0.43635377,0,2,,4.00E-58,Q99504,Eyes absent homolog 3 (EC 3.1.3.48),Eyes absent homolog 3 (EC 3.1.3.48),GO:0009653; GO:0003682; GO:0005737; GO:0006302; GO:0016576; GO:0046872; GO:0007275; GO:0005634; GO:0045739; GO:0004725; GO:0008138; GO:0006355; GO:0010212; GO:0005667; GO:0006351; GO:0007601,"anatomical structure morphogenesis; chromatin binding; cytoplasm; double-strand break repair; histone dephosphorylation; metal ion binding; multicellular organismal development; nucleus; positive regulation of DNA repair; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of transcription, DNA-dependent; response to ionizing radiation; transcription factor complex; transcription, DNA-dependent; visual perception",,,,,,,,,,EYA3_HUMAN,Homo sapiens (Human),"anatomical structure morphogenesis [GO:0009653]; double-strand break repair [GO:0006302]; histone dephosphorylation [GO:0016576]; multicellular organism development [GO:0007275]; positive regulation of DNA repair [GO:0045739]; regulation of transcription, DNA-templated [GO:0006355]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp126458_c0_seq3,560,43.3929,0.45609902,2,0,,,,,,,,,9.00E-14,CHOYP_EYA4.1.1,,,,,,,,, comp126458_c0_seq4,1281,44.6526,0.47864426,2,0,,2.00E-79,Q9Z191,Eyes absent homolog 4 (EC 3.1.3.48),Eyes absent homolog 4 (EC 3.1.3.48),GO:0006281; GO:0016568; GO:0005737; GO:0046872; GO:0042474; GO:0005634; GO:0035335; GO:0004725; GO:0006355; GO:0007605; GO:0006351,"DNA repair; chromatin modification; cytoplasm; metal ion binding; middle ear morphogenesis; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; regulation of transcription, DNA-dependent; sensory perception of sound; transcription, DNA-dependent",,,,,,,,,,EYA4_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; DNA repair [GO:0006281]; middle ear morphogenesis [GO:0042474]; regulation of transcription, DNA-templated [GO:0006355]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]" comp126458_c0_seq5,1227,44.4173,0.48566707,2,3,,3.00E-82,Q99502,Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48),Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48),GO:0009653; GO:0035909; GO:0001658; GO:0034613; GO:0090103; GO:0005737; GO:0006302; GO:0048704; GO:0000132; GO:0035088; GO:0016576; GO:0060487; GO:0046872; GO:0001656; GO:0042474; GO:0043066; GO:0048665; GO:0005634; GO:0071600; GO:0042473; GO:0003151; GO:0007389; GO:0060037; GO:0045739; GO:0045747; GO:0050679; GO:0072513; GO:0045944; GO:0016925; GO:0004725; GO:0045664; GO:0010212; GO:0048752; GO:0007605; GO:0014706; GO:0006351,"anatomical structure morphogenesis; aorta morphogenesis; branching involved in ureteric bud morphogenesis; cellular protein localization; cochlea morphogenesis; cytoplasm; double-strand break repair; embryonic skeletal system morphogenesis; establishment of mitotic spindle orientation; establishment or maintenance of apical/basal cell polarity; histone dephosphorylation; lung epithelial cell differentiation; metal ion binding; metanephros development; middle ear morphogenesis; negative regulation of apoptotic process; neuron fate specification; nucleus; otic vesicle morphogenesis; outer ear morphogenesis; outflow tract morphogenesis; pattern specification process; pharyngeal system development; positive regulation of DNA repair; positive regulation of Notch signaling pathway; positive regulation of epithelial cell proliferation; positive regulation of secondary heart field cardioblast proliferation; positive regulation of transcription from RNA polymerase II promoter; protein sumoylation; protein tyrosine phosphatase activity; regulation of neuron differentiation; response to ionizing radiation; semicircular canal morphogenesis; sensory perception of sound; striated muscle tissue development; transcription, DNA-dependent",,1.00E-72,CHOYP_BRAFLDRAFT_83679.2.2,,,,,,,EYA1_HUMAN,Homo sapiens (Human),"anatomical structure morphogenesis [GO:0009653]; aorta morphogenesis [GO:0035909]; branching involved in ureteric bud morphogenesis [GO:0001658]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; double-strand break repair [GO:0006302]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; histone dephosphorylation [GO:0016576]; lung epithelial cell differentiation [GO:0060487]; mesodermal cell fate specification [GO:0007501]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neuron fate specification [GO:0048665]; otic vesicle morphogenesis [GO:0071600]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of DNA repair [GO:0045739]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein sumoylation [GO:0016925]; regulation of neuron differentiation [GO:0045664]; response to ionizing radiation [GO:0010212]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; striated muscle tissue development [GO:0014706]; transcription, DNA-templated [GO:0006351]" comp126458_c1_seq1,326,40.7975,0.51787818,8,7,,1.00E-60,Q9YH98,Eyes absent homolog 4 (EC 3.1.3.48) (Fragment),Eyes absent homolog 4 (EC 3.1.3.48) (Fragment),GO:0006281; GO:0016568; GO:0005737; GO:0007275; GO:0005634; GO:0035335; GO:0004725; GO:0006355; GO:0006351,"DNA repair; chromatin modification; cytoplasm; multicellular organismal development; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,EYA4_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; DNA repair [GO:0006281]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126462_c0_seq2,409,49.1443,0.69630786,13,212,,1.00E-19,P26932,"Calponin-1 (Calponin, smooth muscle)","Calponin-1 (Calponin, smooth muscle)",GO:0031032,actomyosin structure organization,PF00402;PF00307;,1.00E-11,CHOYP_SMP_078690.2.5,,,,,,,CNN1_CHICK,Gallus gallus (Chicken),actomyosin structure organization [GO:0031032] comp126462_c0_seq3,836,51.1962,0.91978154,58,485,,2.00E-14,P37801,Calponin homolog OV9M,Calponin homolog OV9M,,,PF00402;,7.00E-11,CHOYP_SMP_078690.5.5,,,,,,,CLPH_ONCVO,Onchocerca volvulus, comp126466_c0_seq2,1904,39.2332,0.28822054,0,0,,4.00E-44,Q6ZSM3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_HUMAN,Homo sapiens (Human),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp126466_c0_seq6,2090,38.7081,0.30846402,0,0,,2.00E-48,Q6P2X9,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp126467_c0_seq2,1395,42.7957,0.44272307,65,0,,,,,,,,,1.00E-11,CHOYP_LOC100890479.1.3,,,,,,,,, comp126480_c0_seq1,932,42.9185,0.58312567,254,527,,2.00E-102,Q13148,TAR DNA-binding protein 43 (TDP-43),TAR DNA-binding protein 43 (TDP-43),GO:0070935; GO:0008380; GO:0008219; GO:0003690; GO:0003730; GO:0006397; GO:0043922; GO:0000166; GO:0005634; GO:0003700; GO:0006366,3'-UTR-mediated mRNA stabilization; RNA splicing; cell death; double-stranded DNA binding; mRNA 3'-UTR binding; mRNA processing; negative regulation by host of viral transcription; nucleotide binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,PF00076;,6.00E-44,CHOYP_LOC656201.1.1,,,,,,,TADBP_HUMAN,Homo sapiens (Human),3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; regulation of cell cycle [GO:0051726]; response to endoplasmic reticulum stress [GO:0034976]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp126484_c1_seq1,442,34.1629,1.01071068,20,96,,2.00E-22,O02414,"Dynein light chain LC6, flagellar outer arm","Dynein light chain LC6, flagellar outer arm",GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0007017; GO:0003774,cilium; cytoplasm; dynein complex; microtubule; microtubule-based process; motor activity,PF01221;,7.00E-27,CHOYP_DYL2.3.3,8.00E-30,ruditapes2_c439,,,,,DYL1_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),microtubule-based process [GO:0007017] comp126486_c0_seq1,919,40.5876,0.55577996,38,423,,2.00E-30,B0BM28,Spindle and kinetochore-associated protein 1,Spindle and kinetochore-associated protein 1,GO:0051301; GO:0007059; GO:0000940; GO:0005737; GO:0008017; GO:0007067; GO:0031110; GO:0005876,cell division; chromosome segregation; condensed chromosome outer kinetochore; cytoplasm; microtubule binding; mitosis; regulation of microtubule polymerization or depolymerization; spindle microtubule,PF07160;,,,,,,,,,SKA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; regulation of microtubule polymerization or depolymerization [GO:0031110] comp126487_c0_seq1,474,40.7173,0.51240789,5,45,,4.00E-12,B2AWV6,Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),GO:0004177; GO:0009987; GO:0046872; GO:0008237; GO:0006508,aminopeptidase activity; cellular process; metal ion binding; metallopeptidase activity; proteolysis,PF01321;PF00557;PF16188;,,,,,,,,,AMPP1_PODAN,Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina), comp126490_c0_seq2,1722,42.741,0.6687269,29,17,,2.00E-124,Q1RMU2,Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD),Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD),GO:0016055; GO:0005881; GO:0005829; GO:0031234; GO:0030496; GO:0042347; GO:0032088; GO:0090090; GO:0048471; GO:2001238; GO:0070536; GO:0070507; GO:0007346; GO:0004221; GO:0006511; GO:0004843; GO:0008270,Wnt receptor signaling pathway; cytoplasmic microtubule; cytosol; extrinsic to internal side of plasma membrane; midbody; negative regulation of NF-kappaB import into nucleus; negative regulation of NF-kappaB transcription factor activity; negative regulation of canonical Wnt receptor signaling pathway; perinuclear region of cytoplasm; positive regulation of extrinsic apoptotic signaling pathway; protein K63-linked deubiquitination; regulation of microtubule cytoskeleton organization; regulation of mitotic cell cycle; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding,PF01302;PF00443;,,,,,,,,,CYLD_BOVIN,Bos taurus (Bovine),necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein K63-linked deubiquitination [GO:0070536]; regulation of cilium assembly [GO:1902017]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; ripoptosome assembly involved in necroptotic process [GO:1901026]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] comp126490_c0_seq3,1103,40.6165,0.73382138,0,0,,,,,,,,,2.00E-146,CHOYP_BRAFLDRAFT_230143.1.1,,,,,,,,, comp126490_c1_seq1,201,45.7711,0.67624821,5,14,,1.00E-07,Q10235,Cell polarity protein alp11 (Altered polarity protein 11),Cell polarity protein alp11 (Altered polarity protein 11),GO:0005829; GO:0005874; GO:0000226; GO:0005634; GO:0006457; GO:0007021,cytosol; microtubule; microtubule cytoskeleton organization; nucleus; protein folding; tubulin complex assembly,PF01302;PF14560;,,,,,,,,,ALP11_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic microtubule organization [GO:0031122]; microtubule cytoskeleton organization [GO:0000226]; tubulin complex assembly [GO:0007021] comp126499_c0_seq1,528,43.3712,0.39497404,17,112,,1.00E-46,P54928,Inositol monophosphatase 3 (IMP 3) (IMPase 3) (LeIMP3) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 3),Inositol monophosphatase 3 (IMP 3) (IMPase 3) (LeIMP3) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 3),GO:0006021; GO:0008934; GO:0052832; GO:0052833; GO:0052834; GO:0000287; GO:0046854,inositol biosynthetic process; inositol monophosphate 1-phosphatase activity; inositol monophosphate 3-phosphatase activity; inositol monophosphate 4-phosphatase activity; inositol monophosphate phosphatase activity; magnesium ion binding; phosphatidylinositol phosphorylation,PF00459;,2.00E-14,CHOYP_LOC100891888.1.1,,,,,,,IMP3_SOLLC,Solanum lycopersicum (Tomato) (Lycopersicon esculentum),inositol biosynthetic process [GO:0006021]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165] comp126499_c0_seq2,512,40.0391,0.35463299,16,66,,6.00E-31,P20456,Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1),Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1),GO:0006021; GO:0008934; GO:0052832; GO:0052833; GO:0046855; GO:0046872; GO:0005739; GO:0005634; GO:0006661; GO:0046854; GO:0007165,inositol biosynthetic process; inositol monophosphate 1-phosphatase activity; inositol monophosphate 3-phosphatase activity; inositol monophosphate 4-phosphatase activity; inositol phosphate dephosphorylation; metal ion binding; mitochondrion; nucleus; phosphatidylinositol biosynthetic process; phosphatidylinositol phosphorylation; signal transduction,PF00459;,,,,,,,,,IMPA1_BOVIN,Bos taurus (Bovine),inositol biosynthetic process [GO:0006021]; inositol metabolic process [GO:0006020]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165] comp126503_c0_seq1,1335,39.0262,0.90565644,30,3971,female>male,1.00E-42,P24367,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),GO:0005788; GO:0042277; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum lumen; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,2.00E-83,CHOYP_LOC100374495.1.1,2.00E-68,ruditapes2_c789,,,,,PPIB_CHICK,Gallus gallus (Chicken),chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] comp126523_c0_seq1,1496,35.2941,0.55874271,22,17,,,,,,,,,2.00E-45,CHOYP_LOC101075808.1.1,,,,,,,,, comp126523_c0_seq3,1519,35.1547,0.5760811,0,0,,1.00E-60,Q29RM3,Receptor expression-enhancing protein 5,Receptor expression-enhancing protein 5,GO:0016021,integral to membrane,PF03134;,1.00E-43,CHOYP_BRAFLDRAFT_57028.1.1,,,,,,,REEP5_BOVIN,Bos taurus (Bovine), comp126523_c0_seq4,1543,35.1264,0.56813467,0,0,,2.00E-51,Q32LG5,Receptor expression-enhancing protein 6,Receptor expression-enhancing protein 6,GO:0016021,integral to membrane,PF03134;,2.00E-45,CHOYP_LOC101075808.1.1,,,,,,,REEP6_BOVIN,Bos taurus (Bovine),regulation of intracellular transport [GO:0032386] comp126536_c0_seq2,608,42.4342,0.40453008,6,63,,2.00E-09,Q9HBM0,Vezatin,Vezatin,GO:0001669; GO:0005912; GO:0016337; GO:0043009; GO:0016021; GO:0005634; GO:0005886; GO:0002142,acrosomal vesicle; adherens junction; cell-cell adhesion; chordate embryonic development; integral to membrane; nucleus; plasma membrane; stereocilia ankle link complex,PF12632;,,,,,,,,,VEZA_HUMAN,Homo sapiens (Human),single organismal cell-cell adhesion [GO:0016337] comp126537_c1_seq1,734,35.1499,1.13139795,8,120,,2.00E-32,O46640,Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1),Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1),GO:0047685; GO:0005737,amine sulfotransferase activity; cytoplasm,PF00685;,,,,,,,,,ST3A1_RABIT,Oryctolagus cuniculus (Rabbit), comp126539_c0_seq1,1687,41.968,0.93049596,20,578,,3.00E-135,Q9BH05,Threonine synthase-like 1 (TSH1),Threonine synthase-like 1 (TSH1),,,PF00291;PF01202;PF14821;,1.00E-12,CHOYP_THNS1.1.1,,,,,,,THNS1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp126545_c2_seq1,742,36.5229,0.57731263,44,131,,4.00E-67,O88848,ADP-ribosylation factor-like protein 6,ADP-ribosylation factor-like protein 6,GO:0005525; GO:0007265; GO:0016055; GO:0005879; GO:0042384; GO:0035085; GO:0060170; GO:0045444; GO:0030117; GO:0046872; GO:0005932; GO:0005543; GO:0006471; GO:0051258; GO:0006612,GTP binding; Ras protein signal transduction; Wnt receptor signaling pathway; axonemal microtubule; cilium assembly; cilium axoneme; cilium membrane; fat cell differentiation; membrane coat; metal ion binding; microtubule basal body; phospholipid binding; protein ADP-ribosylation; protein polymerization; protein targeting to membrane,PF00025;,6.00E-30,CHOYP_ARL6.1.2,,,,,,,ARL6_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cilium assembly [GO:0042384]; fat cell differentiation [GO:0045444]; intermembrane transport [GO:0046909]; protein ADP-ribosylation [GO:0006471]; protein localization to cilium [GO:0061512]; protein localization to nonmotile primary cilium [GO:0097499]; protein polymerization [GO:0051258]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; regulation of smoothened signaling pathway [GO:0008589]; retina layer formation [GO:0010842]; Wnt signaling pathway [GO:0016055] comp126562_c0_seq2,1098,51.8215,0.42991106,34,13,,4.00E-28,Q6ZSG1,RING finger protein 165,RING finger protein 165,GO:0008270,zinc ion binding,PF13639;,4.00E-41,CHOYP_RNF165B.1.2,,,,,,,RN165_HUMAN,Homo sapiens (Human),forelimb morphogenesis [GO:0035136]; innervation [GO:0060384]; motor neuron axon guidance [GO:0008045]; multicellular organism aging [GO:0010259]; muscle structure development [GO:0061061]; positive regulation of BMP signaling pathway [GO:0030513]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp126565_c0_seq1,1337,41.7352,0.45778529,40,134,,9.00E-154,Q9V3D2,Coproporphyrinogen-III oxidase (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3),Oxygen-dependent coproporphyrinogen-III oxidase (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3),GO:0004109; GO:0042803; GO:0006782,coproporphyrinogen oxidase activity; protein homodimerization activity; protoporphyrinogen IX biosynthetic process,PF01218;,1.00E-74,CHOYP_HEM6.1.1,,,,,,,HEM6_DROME,Drosophila melanogaster (Fruit fly),heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] comp126573_c0_seq3,1281,37.783,0.69485137,18,7,,3.00E-30,Q9P2E3,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,2.00E-13,CHOYP_ZNFX1.11.12,,,,,,,ZNFX1_HUMAN,Homo sapiens (Human), comp126577_c0_seq1,1098,37.3406,0.50701771,21,148,,1.00E-42,Q8C1B2,TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14),TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14),GO:0003950; GO:0008209; GO:0008210; GO:0060325; GO:0008585; GO:0030097; GO:0001822; GO:0046872; GO:0044236; GO:0006807; GO:0060021; GO:0048008; GO:0009791; GO:0006471; GO:0048705; GO:0048745; GO:0001570,NAD+ ADP-ribosyltransferase activity; androgen metabolic process; estrogen metabolic process; face morphogenesis; female gonad development; hemopoiesis; kidney development; metal ion binding; multicellular organismal metabolic process; nitrogen compound metabolic process; palate development; platelet-derived growth factor receptor signaling pathway; post-embryonic development; protein ADP-ribosylation; skeletal system morphogenesis; smooth muscle tissue development; vasculogenesis,PF00644;,1.00E-16,CHOYP_LOC100374277.2.3,,,,,,,PARPT_MOUSE,Mus musculus (Mouse),androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; multicellular organism metabolic process [GO:0044236]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; protein ADP-ribosylation [GO:0006471]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] comp126580_c0_seq2,542,42.4354,0.45250154,37,105,,2.00E-65,Q5ZJW4,Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking protein homolog B),Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking protein homolog B),GO:0000139; GO:0005789; GO:0033116; GO:0016021; GO:0015031; GO:0016192,Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; protein transport; vesicle-mediated transport,PF13774;PF00957;,8.00E-59,CHOYP_SC22B.1.1,,,,,,,SC22B_CHICK,Gallus gallus (Chicken),ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; regulation of organelle organization [GO:0033043]; vesicle fusion with Golgi apparatus [GO:0048280] comp126581_c0_seq1,1267,35.438,0.90809319,4,4156,female>male,1.00E-15,Q5RJI4,"Protein kinase domain-containing protein, cytoplasmic (EC 2.7.-.-) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)","Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)",GO:0005524; GO:0005794; GO:0030282; GO:0030154; GO:0048566; GO:0048286; GO:0035264; GO:0042997; GO:0060021; GO:0030501; GO:0032332; GO:0004672; GO:0015031; GO:0001501,ATP binding; Golgi apparatus; bone mineralization; cell differentiation; embryonic digestive tract development; lung alveolus development; multicellular organism growth; negative regulation of Golgi to plasma membrane protein transport; palate development; positive regulation of bone mineralization; positive regulation of chondrocyte differentiation; protein kinase activity; protein transport; skeletal system development,PF12260;,,,,,,,,,PKDCC_MOUSE,Mus musculus (Mouse),bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; palate development [GO:0060021]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; skeletal system development [GO:0001501] comp126583_c0_seq1,228,41.6667,0.30863127,13,4,,,,,,,,,1.00E-12,CHOYP_BRAFLDRAFT_80394.4.9,,,,,,,,, comp126585_c0_seq1,731,35.5677,0.48054518,12,127,,,,,,,,,1.00E-19,CHOYP_LACBIDRAFT_294557.1.1,,,,,,,,, comp126588_c0_seq2,1416,37.9237,0.55707534,24,92,,3.00E-62,Q3ZCI8,Receptor expression-enhancing protein 4,Receptor expression-enhancing protein 4,GO:0051301; GO:0005783; GO:0005789; GO:0016021; GO:0005874; GO:0008017; GO:0007067; GO:0007084,cell division; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; microtubule; microtubule binding; mitosis; mitotic nuclear envelope reassembly,PF03134;,2.00E-65,CHOYP_AAEL_AAEL006632.1.1,,,,,,,REEP4_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope reassembly [GO:0007084]; nuclear envelope organization [GO:0006998] comp126594_c3_seq1,784,46.4286,0.31048487,27,60,,2.00E-101,Q23023,Serine/threonine-protein kinase unc-51 (EC 2.7.11.1) (Uncoordinated protein 51),Serine/threonine-protein kinase unc-51 (EC 2.7.11.1) (Uncoordinated protein 51),GO:0005524; GO:0043277; GO:0006914; GO:0030424; GO:0007411; GO:0016477; GO:0040024; GO:0008340; GO:0009792; GO:0043025; GO:0012501; GO:0046777; GO:0004674; GO:0030516; GO:0040014; GO:0032880; GO:0045138,ATP binding; apoptotic cell clearance; autophagy; axon; axon guidance; cell migration; dauer larval development; determination of adult lifespan; embryo development ending in birth or egg hatching; neuronal cell body; programmed cell death; protein autophosphorylation; protein serine/threonine kinase activity; regulation of axon extension; regulation of multicellular organism growth; regulation of protein localization; tail tip morphogenesis,PF12063;PF00069;,1.00E-122,CHOYP_LOC100644361.1.1,,,,,,,UNC51_CAEEL,Caenorhabditis elegans,apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cell migration [GO:0016477]; dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; nematode male tail tip morphogenesis [GO:0045138]; programmed cell death [GO:0012501]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of cell size [GO:0008361]; regulation of multicellular organism growth [GO:0040014]; regulation of protein localization [GO:0032880] comp126596_c0_seq1,522,41.954,0.7699697,15,116,,3.00E-15,Q5EA28,CpG-binding protein (CXXC-type zinc finger protein 1) (PHD finger and CXXC domain-containing protein 1),CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1),GO:0003677; GO:0048188; GO:0016363; GO:0016607; GO:0006355; GO:0006351; GO:0008270,"DNA binding; Set1C/COMPASS complex; nuclear matrix; nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF12269;PF02008;,1.00E-17,CHOYP_LOC590665.1.1,,,,,,,CXXC1_BOVIN,Bos taurus (Bovine),"positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp126603_c0_seq7,815,32.0245,0.91582629,0,0,,5.00E-07,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp126607_c0_seq1,500,43.2,0.44180071,31,18,,8.00E-36,P24668,Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46),Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46),GO:0009986; GO:0016021; GO:0006886; GO:0005770; GO:0005765; GO:0005537; GO:0015578,cell surface; integral to membrane; intracellular protein transport; late endosome; lysosomal membrane; mannose binding; mannose transmembrane transporter activity,PF02157;,,,,,,,,,MPRD_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; secretion of lysosomal enzymes [GO:0033299] comp126608_c0_seq1,1266,36.1769,0.60596533,434,2298,,3.00E-20,Q9C7F5,Nuclear transport factor 2 (NTF-2),Nuclear transport factor 2 (NTF-2),GO:0005737; GO:0015031,cytoplasm; protein transport,PF02136;,,,,,,,,,NTF2_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031] comp126618_c0_seq2,1180,44.4068,0.4463749,36,33,,5.00E-33,Q6PHN1,Coiled-coil domain-containing protein 57,Coiled-coil domain-containing protein 57,,,,2.00E-51,CHOYP_LOC100368744.1.1,,,,,,,CCD57_MOUSE,Mus musculus (Mouse), comp126619_c0_seq1,446,44.6188,0.68811922,3,0,,4.00E-06,B7FNU7,Lissencephaly-1 homolog,Lissencephaly-1 homolog,GO:0051301; GO:0006928; GO:0005737; GO:0000132; GO:0005874; GO:0005875; GO:0005815; GO:0007067; GO:0006810,cell division; cellular component movement; cytoplasm; establishment of mitotic spindle orientation; microtubule; microtubule associated complex; microtubule organizing center; mitosis; transport,PF00400;,,,,,,,,,LIS1_PHATC,Phaeodactylum tricornutum (strain CCAP 1055/1),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic nuclear division [GO:0007067]; transport [GO:0006810] comp126619_c0_seq2,1549,45.836,0.6079115,48,79,,5.00E-176,Q5E9I8,DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23),DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23),GO:0016567,protein ubiquitination,PF00400;,4.00E-106,CHOYP_DCA11.1.1,,,,,,,DCA11_BOVIN,Bos taurus (Bovine),protein ubiquitination [GO:0016567] comp126621_c0_seq1,1253,40.0638,0.43792589,21,151,,8.00E-127,Q96DM3,Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1),Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1),GO:0005765,lysosomal membrane,PF07035;,7.00E-108,CHOYP_BRAFLDRAFT_87849.1.1,,,,,,,MIC1_HUMAN,Homo sapiens (Human), comp126624_c3_seq1,1284,43.8474,0.79479233,16,164,,,,,,,,,4.00E-22,CHOYP_LOC408390.1.1,,,,,,,,, comp126625_c0_seq1,587,41.3969,0.56686571,1,97,,8.00E-17,P51569,Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),GO:0005794; GO:0004557; GO:0005576; GO:0016139; GO:0046477; GO:0005764; GO:0045019; GO:0051001; GO:0009311; GO:0042803; GO:0052692; GO:0005102,Golgi apparatus; alpha-galactosidase activity; extracellular region; glycoside catabolic process; glycosylceramide catabolic process; lysosome; negative regulation of nitric oxide biosynthetic process; negative regulation of nitric-oxide synthase activity; oligosaccharide metabolic process; protein homodimerization activity; raffinose alpha-galactosidase activity; receptor binding,PF16499;,,,,,,,,,AGAL_MOUSE,Mus musculus (Mouse),glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] comp126625_c1_seq1,215,41.3953,0.34653156,0,22,,1.00E-12,Q9QWR8,Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B),Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B),GO:0008456; GO:0004557; GO:0016052; GO:0005737; GO:0016139; GO:0046477; GO:0005764; GO:0009311,alpha-N-acetylgalactosaminidase activity; alpha-galactosidase activity; carbohydrate catabolic process; cytoplasm; glycoside catabolic process; glycosylceramide catabolic process; lysosome; oligosaccharide metabolic process,PF16499;,,,,,,,,,NAGAB_MOUSE,Mus musculus (Mouse),carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139] comp126628_c0_seq1,688,46.9477,0.71754375,20,58,,6.00E-58,Q6ZPT1,Kelch-like protein 9,Kelch-like protein 9,GO:0031463; GO:0000910; GO:0030496; GO:0007067; GO:0016567; GO:0004842,Cul3-RING ubiquitin ligase complex; cytokinesis; midbody; mitosis; protein ubiquitination; ubiquitin-protein ligase activity,PF07707;PF00651;PF01344;,2.00E-130,CHOYP_BRAFLDRAFT_223623.1.1,,,,,,,KLHL9_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp126629_c0_seq1,1311,43.7071,0.48131509,35,48,,8.00E-24,Q8CFF0,Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11),Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11),GO:0003950,NAD+ ADP-ribosyltransferase activity,PF00644;PF02825;,,,,,,,,,PAR11_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] comp126629_c0_seq2,837,46.4755,0.54890908,2,5,,3.00E-06,Q3UPF5,Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13),Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13),GO:0017151; GO:0005794; GO:0003950; GO:0003723; GO:0071360; GO:0005737; GO:0051607; GO:0045087; GO:0046872; GO:0045071; GO:0005634; GO:0005886; GO:0032781; GO:0043123; GO:1900246; GO:0032727; GO:0032728; GO:0061014; GO:0032481; GO:0009615,DEAD/H-box RNA helicase binding; Golgi apparatus; NAD+ ADP-ribosyltransferase activity; RNA binding; cellular response to exogenous dsRNA; cytoplasm; defense response to virus; innate immune response; metal ion binding; negative regulation of viral genome replication; nucleus; plasma membrane; positive regulation of ATPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of RIG-I signaling pathway; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of mRNA catabolic process; positive regulation of type I interferon production; response to virus,PF00644;PF02825;,,,,,,,,,ZCCHV_MOUSE,Mus musculus (Mouse),cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of ATPase activity [GO:0032781]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]; suppression by virus of host molecular function [GO:0039507] comp126632_c0_seq1,562,41.9929,0.93427424,347,68,,2.00E-14,Q9Y5Z4,Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL),Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL),GO:0005737; GO:0005739,cytoplasm; mitochondrion,PF04832;,,,,,,,,,HEBP2_HUMAN,Homo sapiens (Human),negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] comp126652_c0_seq1,543,27.9926,0.66214796,0,0,,,,,,,,,,,2.00E-20,ruditapes_c27568,,,,,,, comp126652_c0_seq4,621,28.6634,0.4713919,0,0,,,,,,,,,,,7.00E-20,ruditapes_c20648,,,,,,, comp126657_c0_seq1,1026,37.4269,0.62105611,22,38,,5.00E-40,Q182S8,Guanylate kinase (EC 2.7.4.8) (GMP kinase),Guanylate kinase (EC 2.7.4.8) (GMP kinase),GO:0005524; GO:0005737; GO:0004385; GO:0006163,ATP binding; cytoplasm; guanylate kinase activity; purine nucleotide metabolic process,PF00625;,,,,,,,,,KGUA_CLOD6,Peptoclostridium difficile (strain 630) (Clostridium difficile), comp126657_c0_seq2,698,41.2607,0.61995693,4,0,,8.00E-77,Q64520,Guanylate kinase (EC 2.7.4.8) (GMP kinase),Guanylate kinase (EC 2.7.4.8) (GMP kinase),GO:0005524; GO:0004385; GO:0006163,ATP binding; guanylate kinase activity; purine nucleotide metabolic process,PF00625;,7.00E-48,CHOYP_GUK1.1.1,,,,,,,KGUA_MOUSE,Mus musculus (Mouse),purine nucleotide metabolic process [GO:0006163] comp126660_c0_seq1,703,38.4068,0.95237214,4,173,,5.00E-36,Q12901,Zinc finger protein 155,Zinc finger protein 155,GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN155_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp126665_c0_seq1,1374,45.6332,0.44893402,3,9,,3.00E-62,A0FGR8,Extended synaptotagmin-2 (E-Syt2) (Chr2Syt),Extended synaptotagmin-2 (E-Syt2) (Chr2Syt),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00168;PF17047;,,,,,,,,,ESYT2_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; lipid transport [GO:0006869] comp126665_c0_seq2,1404,45.4416,0.4847839,3,0,,8.00E-53,Q7ZWU7,Extended synaptotagmin-2-B (E-Syt2-B),Extended synaptotagmin-2-B (E-Syt2-B),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00168;PF17047;,,,,,,,,,EST2B_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897]; lipid transport [GO:0006869] comp126670_c0_seq1,1153,38.6817,0.5312079,60,537,,2.00E-78,Q99LZ3,"DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]","DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]",GO:0006260; GO:0005737; GO:0005634,DNA replication; cytoplasm; nucleus,PF05916;PF16922;,1.00E-59,CHOYP_LOC100373647.1.1,,,,,,,SLD5_MOUSE,Mus musculus (Mouse),DNA duplex unwinding [GO:0032508]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; inner cell mass cell proliferation [GO:0001833] comp126674_c0_seq1,1281,41.6862,0.57662555,7,0,,1.00E-178,Q63553,SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase),SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase),GO:0005524; GO:0000287; GO:0005634; GO:0004674; GO:0043523,ATP binding; magnesium ion binding; nucleus; protein serine/threonine kinase activity; regulation of neuron apoptotic process,PF00069;,6.00E-147,CHOYP_LOC100742095.2.2,,,,,,,SNRK_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of neuron apoptotic process [GO:0043523] comp126674_c0_seq2,3185,39.5918,0.52276648,0,0,,7.00E-65,Q54DF2,Probable serine/threonine-protein kinase MARK-A (EC 2.7.11.1),Probable serine/threonine-protein kinase MARK-A (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF02149;PF00069;,,,,,,,,,MRKA_DICDI,Dictyostelium discoideum (Slime mold), comp126674_c0_seq3,2615,41.7208,0.55749884,0,0,,8.00E-174,Q9NRH2,SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase),SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase),GO:0005524; GO:0000287; GO:0030099; GO:0005634; GO:0004674,ATP binding; magnesium ion binding; myeloid cell differentiation; nucleus; protein serine/threonine kinase activity,PF00069;,1.00E-146,CHOYP_CPIPJ_CPIJ003599.1.1,,,,,,,SNRK_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; myeloid cell differentiation [GO:0030099]; protein phosphorylation [GO:0006468] comp126679_c0_seq1,776,38.9175,0.20478839,99,789,,4.00E-06,Q5I034,Uncharacterized protein C12orf43 homolog,Uncharacterized protein C12orf43 homolog,,,,,,,,,,,,CL043_RAT,Rattus norvegicus (Rat), comp126683_c0_seq1,697,40.0287,0.69369324,41,960,,2.00E-65,P54353,Putative peptidyl-prolyl cis-trans isomerase dodo (PPIase dodo) (EC 5.2.1.8) (Rotamase dodo),Putative peptidyl-prolyl cis-trans isomerase dodo (PPIase dodo) (EC 5.2.1.8) (Rotamase dodo),GO:0007173; GO:0005634; GO:0003755; GO:0006457,epidermal growth factor receptor signaling pathway; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00639;PF00397;,1.00E-57,CHOYP_ND5.1.6,,,,,,,DOD_DROME,Drosophila melanogaster (Fruit fly),epidermal growth factor receptor signaling pathway [GO:0007173] comp126683_c0_seq2,885,39.209,0.71639469,14,842,,7.00E-06,Q15QB3,Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA),Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA),GO:0043165; GO:0042710; GO:0051085; GO:0060274; GO:0030288; GO:0042277; GO:0003755; GO:0000413; GO:0050821,Gram-negative-bacterium-type cell outer membrane assembly; biofilm formation; chaperone mediated protein folding requiring cofactor; maintenance of stationary phase; outer membrane-bounded periplasmic space; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein peptidyl-prolyl isomerization; protein stabilization,PF00639;PF09312;,,,,,,,,,SURA_PSEA6,Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087),chaperone mediated protein folding requiring cofactor [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein stabilization [GO:0050821] comp126684_c0_seq1,1026,48.8304,0.47669625,8,49,,3.00E-55,A9JTP3,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,5.00E-20,CHOYP_BIRC7.5.5,,,,,,,BIRC7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966] comp126684_c0_seq2,500,48.2,0.45513809,3,0,,,,,,,,,1.00E-11,CHOYP_BIRC7.5.5,,,,,,,,, comp126686_c0_seq2,1892,41.649,0.4442881,65,150,,8.00E-121,Q6NRL2,Sorting nexin-33 (SH3 and PX domain-containing protein 3),Sorting nexin-33 (SH3 and PX domain-containing protein 3),GO:0007154; GO:0036089; GO:0016023; GO:0030659; GO:0005829; GO:0016197; GO:0007032; GO:0019898; GO:0044351; GO:0097320; GO:0007067; GO:0000281; GO:0035091; GO:0015031,cell communication; cleavage furrow formation; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle membrane; cytosol; endosomal transport; endosome organization; extrinsic to membrane; macropinocytosis; membrane tubulation; mitosis; mitotic cytokinesis; phosphatidylinositol binding; protein transport,PF10456;PF00787;PF14604;,1.00E-100,CHOYP_BRAFLDRAFT_126596.1.1,,,,,,,SNX33_XENLA,Xenopus laevis (African clawed frog),cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; macropinocytosis [GO:0044351]; membrane tubulation [GO:0097320]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067] comp1266_c0_seq1,205,36.0976,0.45176514,1,0,,2.00E-14,Q60806,Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3),Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3),GO:0005524; GO:0000082; GO:0090166; GO:0005795; GO:0006915; GO:0000075; GO:0005813; GO:0000084; GO:0043066; GO:0000122; GO:0005730; GO:0002039; GO:2000777; GO:0043491; GO:0004674; GO:0006974; GO:0006970; GO:0009314; GO:0000302,ATP binding; G1/S transition of mitotic cell cycle; Golgi disassembly; Golgi stack; apoptotic process; cell cycle checkpoint; centrosome; mitotic S phase; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleolus; p53 binding; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; protein kinase B signaling cascade; protein serine/threonine kinase activity; response to DNA damage stimulus; response to osmotic stress; response to radiation; response to reactive oxygen species,PF00069;PF00659;,,,,,,,,,PLK3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; G1/S transition of mitotic cell cycle [GO:0000082]; Golgi disassembly [GO:0090166]; mitotic G1/S transition checkpoint [GO:0044819]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cell division [GO:0051302]; regulation of cytokinesis [GO:0032465]; response to osmotic stress [GO:0006970]; response to radiation [GO:0009314]; response to reactive oxygen species [GO:0000302] comp126700_c1_seq2,1148,43.1185,0.37626514,27,98,,4.00E-15,Q9Y3T6,R3H and coiled-coil domain-containing protein 1,R3H and coiled-coil domain-containing protein 1,GO:0003676; GO:0000166,nucleic acid binding; nucleotide binding,PF01424;,,,,,,,,,R3HC1_HUMAN,Homo sapiens (Human), comp126701_c0_seq1,345,40.5797,0.49519942,3,31,,2.00E-21,Q8BN82,Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),GO:0006865; GO:0030054; GO:0016023; GO:0016021; GO:0005765; GO:0005886; GO:0015136; GO:0015739; GO:0015293; GO:0030672,amino acid transport; cell junction; cytoplasmic membrane-bounded vesicle; integral to membrane; lysosomal membrane; plasma membrane; sialic acid transmembrane transporter activity; sialic acid transport; symporter activity; synaptic vesicle membrane,PF07690;,,,,,,,,,S17A5_MOUSE,Mus musculus (Mouse),amino acid transport [GO:0006865]; sialic acid transport [GO:0015739] comp126701_c1_seq2,786,38.2952,0.55593909,8,25,,2.00E-13,Q03567,Uncharacterized transporter C38C10.2,Uncharacterized transporter slc-17.2,GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,YLD2_CAEEL,Caenorhabditis elegans,anion transport [GO:0006820]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085] comp126710_c0_seq1,1320,38.5606,0.35211222,35,247,,4.00E-20,Q9P209,Centrosomal protein of 72 kDa (Cep72),Centrosomal protein of 72 kDa (Cep72),GO:0000086; GO:0005813; GO:0005829; GO:0033566; GO:0007051,G2/M transition of mitotic cell cycle; centrosome; cytosol; gamma-tubulin complex localization; spindle organization,,,,,,,,,,CEP72_HUMAN,Homo sapiens (Human),centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gamma-tubulin complex localization [GO:0033566]; regulation of protein localization to centrosome [GO:1904779]; spindle organization [GO:0007051] comp126713_c0_seq2,953,40.9234,0.3351805,28,150,,1.00E-06,O15014,Zinc finger protein 609,Zinc finger protein 609,GO:0046872; GO:0005634,metal ion binding; nucleus,,,,,,,,,,ZN609_HUMAN,Homo sapiens (Human), comp126716_c1_seq1,640,38.125,0.53760265,0,0,,3.00E-11,P13993,Repetitive proline-rich cell wall protein 2,Repetitive proline-rich cell wall protein 2,GO:0005618; GO:0005576; GO:0007275; GO:0005199,cell wall; extracellular region; multicellular organismal development; structural constituent of cell wall,PF02095;,,,,,,,,,PRP2_SOYBN,Glycine max (Soybean) (Glycine hispida),multicellular organism development [GO:0007275] comp126716_c1_seq2,667,37.7811,0.52736961,11,12,,7.00E-10,P08012,Repetitive proline-rich cell wall protein 1,Repetitive proline-rich cell wall protein 1,GO:0005618; GO:0005576; GO:0007275; GO:0005199,cell wall; extracellular region; multicellular organismal development; structural constituent of cell wall,PF02095;,,,,,,,,,PRP1_SOYBN,Glycine max (Soybean) (Glycine hispida),multicellular organism development [GO:0007275] comp126716_c1_seq4,643,37.325,0.47297412,0,0,,3.00E-11,P13993,Repetitive proline-rich cell wall protein 2,Repetitive proline-rich cell wall protein 2,GO:0005618; GO:0005576; GO:0007275; GO:0005199,cell wall; extracellular region; multicellular organismal development; structural constituent of cell wall,PF02095;,,,,,,,,,PRP2_SOYBN,Glycine max (Soybean) (Glycine hispida),multicellular organism development [GO:0007275] comp126722_c1_seq1,701,47.3609,0.50967541,2,0,,,,,,,,,,,1.00E-73,ruditapes_c13715,,,,,,, comp126722_c1_seq2,944,47.1398,0.53461086,2,8,,3.00E-64,Q86X27,Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2),Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2),GO:0005737; GO:0005085; GO:0005543; GO:0005886; GO:0007264,cytoplasm; guanyl-nucleotide exchange factor activity; phospholipid binding; plasma membrane; small GTPase mediated signal transduction,PF00169;PF00617;,,,,,,,,,RGPS2_HUMAN,Homo sapiens (Human),regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264] comp126722_c1_seq3,929,47.1475,0.54322493,1,13,,3.00E-69,Q5ZJK0,Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (RalA exchange factor RalGPS1),Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (RalA exchange factor RalGPS1),GO:0005737; GO:0005085; GO:0005543; GO:0005886; GO:0007264,cytoplasm; guanyl-nucleotide exchange factor activity; phospholipid binding; plasma membrane; small GTPase mediated signal transduction,PF00169;PF00617;,,,,,,,,,RGPS1_CHICK,Gallus gallus (Chicken),regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264] comp126722_c2_seq1,404,41.0891,0.94118224,34,17,,4.00E-20,P26674,Protein ste6,Protein ste6,GO:0005829; GO:0005085; GO:0000750; GO:0051056; GO:0007264,cytosol; guanyl-nucleotide exchange factor activity; pheromone-dependent signal transduction involved in conjugation with cellular fusion; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00617;PF00618;PF00018;,8.00E-57,CHOYP_RGPS1.1.1,,,,,,,STE6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),conjugation with cellular fusion [GO:0000747]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; small GTPase mediated signal transduction [GO:0007264] comp126725_c0_seq2,938,38.0597,0.42585082,26,25,,1.00E-10,Q70EL2,Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45),Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45),GO:0008234; GO:0004221; GO:0006511; GO:0008270,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF00443;PF02148;,,,,,,,,,UBP45_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp126725_c1_seq1,1082,41.5896,0.43092509,16,28,,3.00E-49,Q70EL2,Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45),Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45),GO:0008234; GO:0004221; GO:0006511; GO:0008270,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF00443;PF02148;,2.00E-57,CHOYP_LOC585494.1.1,,,,,,,UBP45_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp126727_c0_seq1,995,43.0151,0.26621552,21,127,,7.00E-79,Q0E2Y1,(6-4)DNA photolyase (EC 4.1.99.13),(6-4)DNA photolyase (EC 4.1.99.13),GO:0003914; GO:0003677; GO:0006281; GO:0000166,DNA (6-4) photolyase activity; DNA binding; DNA repair; nucleotide binding,PF00875;PF03441;,3.00E-93,CHOYP_XL64PHR.1.1,,,,,,,UVR3_ORYSJ,Oryza sativa subsp. japonica (Rice),DNA repair [GO:0006281] comp126727_c1_seq1,938,42.6439,0.44791796,15,18,,1.00E-105,Q32Q86,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0007623; GO:0003690; GO:0005739; GO:0000122; GO:0000166; GO:0005634; GO:0009881; GO:0000988; GO:0018298; GO:0042752; GO:0006351,"DNA photolyase activity; DNA repair; circadian rhythm; double-stranded DNA binding; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; nucleotide binding; nucleus; photoreceptor activity; protein binding transcription factor activity; protein-chromophore linkage; regulation of circadian rhythm; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY1_RAT,Rattus norvegicus (Rat),"circadian regulation of gene expression [GO:0032922]; DNA damage induced protein phosphorylation [GO:0006975]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; transcription, DNA-templated [GO:0006351]" comp126739_c0_seq1,824,40.1699,1.26644923,70,48,,8.00E-24,Q5WA50,Cephalotocin receptor 2,Cephalotocin receptor 2,GO:0016021; GO:0005886; GO:0046887; GO:0016500; GO:0005000,integral to membrane; plasma membrane; positive regulation of hormone secretion; protein-hormone receptor activity; vasopressin receptor activity,PF00001;,,,,,,,,,CTR2_OCTVU,Octopus vulgaris (Common octopus),G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of hormone secretion [GO:0046887] comp126742_c1_seq1,839,45.4112,0.44271908,31,62,,4.00E-107,Q60790,Ras GTPase-activating protein 3 (GAP1(IP4BP)) (GapIII) (Ins P4-binding protein),Ras GTPase-activating protein 3 (GAP1(IP4BP)) (GapIII) (Ins P4-binding protein),GO:0005099; GO:0015278; GO:0005737; GO:0035556; GO:0031235; GO:0046872; GO:0046580; GO:0005543,Ras GTPase activator activity; calcium-release channel activity; cytoplasm; intracellular signal transduction; intrinsic to internal side of plasma membrane; metal ion binding; negative regulation of Ras protein signal transduction; phospholipid binding,PF00779;PF00168;PF00169;PF00616;,,,,,,,,,RASA3_MOUSE,Mus musculus (Mouse),cellular response to heat [GO:0034605]; negative regulation of Ras protein signal transduction [GO:0046580] comp126744_c0_seq1,1892,43.4461,0.42718193,68,35,,5.00E-135,Q92783,Signal transducing adapter molecule 1 (STAM-1),Signal transducing adapter molecule 1 (STAM-1),GO:0005070; GO:0005829; GO:0031901; GO:0016197; GO:0007173; GO:0006886; GO:0042059,SH3/SH2 adaptor activity; cytosol; early endosome membrane; endosomal transport; epidermal growth factor receptor signaling pathway; intracellular protein transport; negative regulation of epidermal growth factor receptor signaling pathway,PF00018;PF02809;PF00790;,2.00E-85,CHOYP_LOC100373138.1.1,,,,,,,STAM1_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of exosomal secretion [GO:1903543]; regulation of extracellular exosome assembly [GO:1903551]; signal transduction [GO:0007165] comp126758_c0_seq1,874,36.9565,0.54390126,0,0,,2.00E-11,Q3SZA1,Rho-related GTP-binding protein RhoF,Rho-related GTP-binding protein RhoF,GO:0005525; GO:0007015; GO:0005737; GO:0005856; GO:0005886; GO:0007264,GTP binding; actin filament organization; cytoplasm; cytoskeleton; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RHOF_BOVIN,Bos taurus (Bovine),actin filament organization [GO:0007015]; small GTPase mediated signal transduction [GO:0007264] comp126758_c0_seq2,961,35.2758,0.54220152,14,22,,4.00E-72,Q9VND8,GTP-binding protein Rheb homolog,GTP-binding protein Rheb homolog,GO:0000082; GO:0005525; GO:0003924; GO:0007411; GO:0016049; GO:0042331; GO:0005886; GO:0030307; GO:0045793; GO:0090070; GO:0045727; GO:0010506; GO:2000377; GO:0042594; GO:0042254; GO:0007264; GO:0051124,G1/S transition of mitotic cell cycle; GTP binding; GTPase activity; axon guidance; cell growth; phototaxis; plasma membrane; positive regulation of cell growth; positive regulation of cell size; positive regulation of ribosome biogenesis; positive regulation of translation; regulation of autophagy; regulation of reactive oxygen species metabolic process; response to starvation; ribosome biogenesis; small GTPase mediated signal transduction; synaptic growth at neuromuscular junction,PF00071;,1.00E-71,CHOYP_LOC100533537.1.1,,,,,,,RHEB_DROME,Drosophila melanogaster (Fruit fly),"apical protein localization [GO:0045176]; axon guidance [GO:0007411]; carbohydrate metabolic process [GO:0005975]; cell growth [GO:0016049]; G1/S transition of mitotic cell cycle [GO:0000082]; imaginal disc growth [GO:0007446]; lipid metabolic process [GO:0006629]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; phototaxis [GO:0042331]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of ribosome biogenesis [GO:0090070]; positive regulation of TOR signaling [GO:0032008]; positive regulation of translation [GO:0045727]; regulation of autophagy [GO:0010506]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to starvation [GO:0042594]; ribosome biogenesis [GO:0042254]; small GTPase mediated signal transduction [GO:0007264]; synaptic growth at neuromuscular junction [GO:0051124]; terminal branching, open tracheal system [GO:0007430]" comp126759_c0_seq1,772,36.399,0.66814226,16,105,,2.00E-07,B3DMA2,Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-),Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-),GO:0033539; GO:0050660; GO:0070991; GO:0031966; GO:0005634; GO:0005777; GO:0016772; GO:0017099,"fatty acid beta-oxidation using acyl-CoA dehydrogenase; flavin adenine dinucleotide binding; medium-chain-acyl-CoA dehydrogenase activity; mitochondrial membrane; nucleus; peroxisome; transferase activity, transferring phosphorus-containing groups; very-long-chain-acyl-CoA dehydrogenase activity",PF00441;PF02770;PF02771;PF01636;,,,,,,,,,ACD11_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp126761_c1_seq1,2819,41.646,0.59957368,81,403,,3.00E-12,Q14678,KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein),KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein),GO:0008013; GO:0005737; GO:0035024; GO:0030837; GO:0030336; GO:0046627; GO:2000393; GO:0010977; GO:1900028; GO:1900025; GO:0005634; GO:0030177; GO:0035413; GO:0090303; GO:2000114; GO:0006355; GO:0032587; GO:0006351,"beta-catenin binding; cytoplasm; negative regulation of Rho protein signal transduction; negative regulation of actin filament polymerization; negative regulation of cell migration; negative regulation of insulin receptor signaling pathway; negative regulation of lamellipodium morphogenesis; negative regulation of neuron projection development; negative regulation of ruffle assembly; negative regulation of substrate adhesion-dependent cell spreading; nucleus; positive regulation of Wnt receptor signaling pathway; positive regulation of catenin import into nucleus; positive regulation of wound healing; regulation of establishment of cell polarity; regulation of transcription, DNA-dependent; ruffle membrane; transcription, DNA-dependent",PF12796;PF12075;,9.00E-16,CHOYP_LOC100218754.1.1,,,,,,,KANK1_HUMAN,Homo sapiens (Human),"negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp126762_c0_seq2,702,43.4473,0.55852868,17,6,,4.00E-54,Q8K2C7,Protein OS-9,Protein OS-9,GO:0030433; GO:0005788; GO:0001948; GO:0006621; GO:0006605; GO:0042787; GO:0034976,ER-associated protein catabolic process; endoplasmic reticulum lumen; glycoprotein binding; protein retention in ER lumen; protein targeting; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to endoplasmic reticulum stress,PF07915;,1.00E-50,CHOYP_OS9.1.1,,,,,,,OS9_MOUSE,Mus musculus (Mouse),"ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein retention in ER lumen [GO:0006621]; protein targeting [GO:0006605]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; retrograde protein transport, ER to cytosol [GO:0030970]" comp126763_c0_seq3,228,40.3509,0.21809943,2,0,,,,,,,,,2.00E-11,CHOYP_LOC100123553.1.1,,,,,,,,, comp126766_c0_seq1,1308,37.9205,0.49376003,217,1586,,2.00E-09,O57594,Surfeit locus protein 6 homolog,Surfeit locus protein 6 homolog,GO:0005730,nucleolus,PF04935;,,,,,,,,,SURF6_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes), comp126767_c0_seq2,309,38.835,0.35237652,5,5,,3.00E-06,Q9Y7V2,Transcription factor bye1,Transcription factor bye1,GO:0034244; GO:0005634; GO:0019787; GO:0006351; GO:0008270,"negative regulation of transcription elongation from RNA polymerase II promoter; nucleus; small conjugating protein ligase activity; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,,,,,,,,,BYE1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; transcription, DNA-templated [GO:0006351]" comp126770_c0_seq1,701,41.2268,0.53824146,34,83,,3.00E-24,Q92664,Transcription factor IIIA (TFIIIA),Transcription factor IIIA (TFIIIA),GO:0003677; GO:0003723; GO:0046872; GO:0005654; GO:0009303; GO:0006355; GO:0006383,"DNA binding; RNA binding; metal ion binding; nucleoplasm; rRNA transcription; regulation of transcription, DNA-dependent; transcription from RNA polymerase III promoter",,,,,,,,,,TF3A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; rRNA transcription [GO:0009303]; transcription from RNA polymerase III promoter [GO:0006383]" comp126777_c0_seq1,976,38.7295,0.68653978,1239,5890,,6.00E-101,Q9D0I8,mRNA turnover protein 4 homolog,mRNA turnover protein 4 homolog (Ribosome assembly factor Mrto4),GO:0005730; GO:0042254,nucleolus; ribosome biogenesis,PF00466;,6.00E-63,CHOYP_MRT4.1.1,3.00E-135,ruditapes_c15407,,,,,MRT4_MOUSE,Mus musculus (Mouse),nuclear-transcribed mRNA catabolic process [GO:0000956]; ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] comp126778_c2_seq1,731,39.1245,0.61045,34,19,,2.00E-43,Q3KTM2,Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2),Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2),GO:0012505; GO:0006071; GO:0008889; GO:0030426; GO:0016021; GO:0006629; GO:0045746; GO:0007399; GO:0048471,endomembrane system; glycerol metabolic process; glycerophosphodiester phosphodiesterase activity; growth cone; integral to membrane; lipid metabolic process; negative regulation of Notch signaling pathway; nervous system development; perinuclear region of cytoplasm,PF03009;,,,,,,,,,GDPD5_CHICK,Gallus gallus (Chicken),lipid metabolic process [GO:0006629]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of neuron differentiation [GO:0045666] comp126780_c0_seq1,1840,38.6413,0.55793234,2549,12523,,3.00E-146,P57093,"Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH)","Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH)",GO:0031418; GO:0048037; GO:0001561; GO:0006720; GO:0046872; GO:0097089; GO:0005739; GO:0005777; GO:0048244,L-ascorbic acid binding; cofactor binding; fatty acid alpha-oxidation; isoprenoid metabolic process; metal ion binding; methyl-branched fatty acid metabolic process; mitochondrion; peroxisome; phytanoyl-CoA dioxygenase activity,PF05721;,1.00E-68,CHOYP_LOC100690874.2.2,,,,,,,PAHX_RAT,Rattus norvegicus (Rat),fatty acid alpha-oxidation [GO:0001561]; isoprenoid metabolic process [GO:0006720]; methyl-branched fatty acid metabolic process [GO:0097089] comp126788_c0_seq1,254,52.3622,0.74967241,0,2,,1.00E-12,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp126789_c0_seq1,704,39.4886,0.39783388,746,89,,,,,,,,,3.00E-21,CHOYP_LOC100371736.1.1,,,,,,,,, comp126795_c0_seq3,893,44.6809,0.59618419,2,2,,2.00E-152,P30628,Probable V-type proton ATPase 116 kDa subunit a (V-ATPase 116 kDa isoform a) (Uncoordinated protein 32) (Vacuolar proton translocating ATPase 116 kDa subunit a),Probable V-type proton ATPase 116 kDa subunit a (V-ATPase 116 kDa isoform a) (Uncoordinated protein 32) (Vacuolar proton translocating ATPase 116 kDa subunit a),GO:0015991; GO:0015986; GO:0009792; GO:0015078; GO:0016021; GO:0040011; GO:0040013; GO:0002119; GO:0043068; GO:0001666; GO:0007271; GO:0016471; GO:0000220,"ATP hydrolysis coupled proton transport; ATP synthesis coupled proton transport; embryo development ending in birth or egg hatching; hydrogen ion transmembrane transporter activity; integral to membrane; locomotion; negative regulation of locomotion; nematode larval development; positive regulation of programmed cell death; response to hypoxia; synaptic transmission, cholinergic; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_LOC100741247.1.2,,,,,,,VPP1_CAEEL,Caenorhabditis elegans,"ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; negative regulation of locomotion [GO:0040013]; nematode larval development [GO:0002119]; positive regulation of programmed cell death [GO:0043068]; response to hypoxia [GO:0001666]; synaptic transmission, cholinergic [GO:0007271]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]" comp126795_c0_seq4,585,44.9573,0.58223431,2,0,,,,,,,,,2.00E-35,CHOYP_VPP1.2.2,,,,,,,,, comp126795_c1_seq1,432,45.3704,0.58611309,7,6,,4.00E-38,P37296,"V-type proton ATPase subunit a, Golgi isoform (V-ATPase a 2 subunit) (Similar to VPH1 protein 1) (V-ATPase 101 kDa subunit) (V-ATPase subunit AC115) (Vacuolar proton translocating ATPase subunit a 2)","V-type proton ATPase subunit a, Golgi isoform (V-ATPase a 2 subunit) (Similar to VPH1 protein 1) (V-ATPase 101 kDa subunit) (V-ATPase subunit AC115) (Vacuolar proton translocating ATPase subunit a 2)",GO:0015991; GO:0005794; GO:0000139; GO:0010008; GO:0016021; GO:0005770; GO:0046961; GO:0007035; GO:0000220,"ATP hydrolysis coupled proton transport; Golgi apparatus; Golgi membrane; endosome membrane; integral to membrane; late endosome; proton-transporting ATPase activity, rotational mechanism; vacuolar acidification; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,,,,,,,,,STV1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp126796_c0_seq3,1013,40.2764,0.2200523,16,0,,1.00E-06,Q8C428,Transmembrane channel-like protein 7,Transmembrane channel-like protein 7,GO:0016021; GO:0006811,integral to membrane; ion transport,PF07810;,,,,,,,,,TMC7_MOUSE,Mus musculus (Mouse),ion transport [GO:0006811] comp126797_c0_seq1,1233,38.7672,0.44516624,4,0,,3.00E-17,F6QXW0,DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],GO:0051539; GO:0043139; GO:0017108; GO:0005524; GO:0003677; GO:0000729; GO:0000076; GO:0033567; GO:0046872; GO:0005739; GO:0005634; GO:0043142,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; 5'-flap endonuclease activity; ATP binding; DNA binding; DNA double-strand break processing; DNA replication checkpoint; DNA replication, Okazaki fragment processing; metal ion binding; mitochondrion; nucleus; single-stranded DNA-dependent ATPase activity",PF08696;,,,,,,,,,DNA2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication checkpoint [GO:0000076]" comp126797_c1_seq1,1399,43.0307,0.48038101,4,0,,2.00E-11,O94247,DNA polymerase alpha-associated DNA helicase A (EC 3.6.4.12),DNA polymerase alpha-associated DNA helicase A (EC 3.6.4.12),GO:0005524; GO:0043141; GO:0033203; GO:0005829; GO:0006273,ATP binding; ATP-dependent 5'-3' DNA helicase activity; DNA helicase A complex; cytosol; lagging strand elongation,,4.00E-36,CHOYP_DNA2.1.5,,,,,,,HCS1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mitotic DNA replication lagging strand elongation [GO:1903459] comp126797_c1_seq2,1442,43.5506,0.47265008,10,16,,1.00E-112,Q8QHA5,DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],GO:0051539; GO:0043139; GO:0017108; GO:0005524; GO:0003677; GO:0000729; GO:0000076; GO:0043137; GO:0006284; GO:0046872; GO:0006264; GO:0005739; GO:0005634; GO:0045740; GO:0043142; GO:0016890,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; 5'-flap endonuclease activity; ATP binding; DNA binding; DNA double-strand break processing; DNA replication checkpoint; DNA replication, removal of RNA primer; base-excision repair; metal ion binding; mitochondrial DNA replication; mitochondrion; nucleus; positive regulation of DNA replication; single-stranded DNA-dependent ATPase activity; site-specific endodeoxyribonuclease activity, specific for altered base",PF08696;,,,,,,,,,DNA2_XENLA,Xenopus laevis (African clawed frog),"base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; DNA replication checkpoint [GO:0000076]; double-strand break repair via single-strand annealing [GO:0045002]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740]" comp126799_c0_seq1,1051,37.5833,0.46300461,71,316,,8.00E-57,A5PLF5,TM2 domain-containing protein 3,TM2 domain-containing protein 3,GO:0016021,integral to membrane,PF05154;,2.00E-37,CHOYP_BRAFLDRAFT_85791.1.1,,,,,,,TM2D3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126800_c0_seq1,358,34.6369,1.3075024,7,47,,,,,,,,,,,2.00E-23,ruditapes_c12650,,,,,,, comp126801_c1_seq1,952,39.4958,0.51347039,21,39,,3.00E-55,Q15075,Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2),Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2),GO:0005545; GO:0030742; GO:0005516; GO:0005829; GO:0005769; GO:0031901; GO:0045022; GO:0019897; GO:0042803; GO:0055037; GO:0005969; GO:0016189; GO:0006906; GO:0008270,1-phosphatidylinositol binding; GTP-dependent protein binding; calmodulin binding; cytosol; early endosome; early endosome membrane; early endosome to late endosome transport; extrinsic to plasma membrane; protein homodimerization activity; recycling endosome; serine-pyruvate aminotransferase complex; synaptic vesicle to endosome fusion; vesicle fusion; zinc ion binding,PF01363;,6.00E-44,CHOYP_EEA1.1.1,4.00E-69,ruditapes_c10806,,,,,EEA1_HUMAN,Homo sapiens (Human),early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] comp126803_c0_seq1,2448,40.5637,0.63822278,67,294,,4.00E-118,Q92738,USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre),USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre),GO:0005794; GO:0007030; GO:0005097; GO:0016023; GO:0031410; GO:0035526,"Golgi apparatus; Golgi organization; Rab GTPase activator activity; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; retrograde transport, plasma membrane to Golgi",PF00566;,2.00E-98,CHOYP_PHUM_PHUM537100.1.1,,,,,,,US6NL_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; regulation of Golgi organization [GO:1903358]; regulation of vesicle fusion [GO:0031338]; retrograde transport, plasma membrane to Golgi [GO:0035526]; virion assembly [GO:0019068]" comp126804_c0_seq1,943,51.2195,0.23251258,5,0,,,,,,,,,2.00E-12,CHOYP_EVL.1.1,,,,,,,,, comp126804_c0_seq2,1882,41.7109,0.28189365,92,52,,,,,,,,,5.00E-11,CHOYP_DVIR_GJ19769.1.1,,,,,,,,, comp126807_c0_seq1,1053,40.7407,0.67107288,4,124,,1.00E-08,Q09918,Uncharacterized protein C1F7.06,Putative glutathione-independent glyoxalase hsp3105 (EC 4.2.1.130) (Glyoxalase 3 homolog 5) (Heat shock protein 31 homolog 5),GO:0005829; GO:0005634,cytosol; nucleus,PF01965;,,,,,,,,,YAK6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] comp126807_c0_seq2,1015,40.2956,0.64163288,5,24,,5.00E-36,Q09675,Uncharacterized protein C5H10.02c (EC 3.2.-.-),Glutathione-independent glyoxalase hsp3102 (EC 4.2.1.130) (Glyoxalase 3 homolog 2) (Heat shock protein 31 homolog 2),GO:0034599; GO:0005829; GO:0005634; GO:0008233; GO:0006508,cellular response to oxidative stress; cytosol; nucleus; peptidase activity; proteolysis,PF01965;,3.00E-36,CHOYP_LOC100199980.1.2,,,,,,,YA02_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular detoxification [GO:1990748]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] comp126810_c0_seq2,778,44.7301,0.66900193,6,8,,3.00E-48,Q9BX95,Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (hSPP1) (hSPPase1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1),Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (hSPP1) (hSPPase1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1),GO:0006915; GO:0005789; GO:0016021; GO:0044281; GO:0006668; GO:0030148; GO:0006670; GO:0042392,apoptotic process; endoplasmic reticulum membrane; integral to membrane; small molecule metabolic process; sphinganine-1-phosphate metabolic process; sphingolipid biosynthetic process; sphingosine metabolic process; sphingosine-1-phosphate phosphatase activity,PF01569;,,,,,,,,,SGPP1_HUMAN,Homo sapiens (Human),extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway [GO:0097193]; sphinganine-1-phosphate metabolic process [GO:0006668]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670] comp126810_c0_seq3,415,46.2651,0.72348246,0,0,,1.00E-12,Q9BX95,Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (hSPP1) (hSPPase1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1),Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (hSPP1) (hSPPase1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1),GO:0006915; GO:0005789; GO:0016021; GO:0044281; GO:0006668; GO:0030148; GO:0006670; GO:0042392,apoptotic process; endoplasmic reticulum membrane; integral to membrane; small molecule metabolic process; sphinganine-1-phosphate metabolic process; sphingolipid biosynthetic process; sphingosine metabolic process; sphingosine-1-phosphate phosphatase activity,PF01569;,,,,,,,,,SGPP1_HUMAN,Homo sapiens (Human),extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway [GO:0097193]; sphinganine-1-phosphate metabolic process [GO:0006668]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670] comp126825_c2_seq2,209,45.933,0.18518942,4,3,,1.00E-07,P13993,Repetitive proline-rich cell wall protein 2,Repetitive proline-rich cell wall protein 2,GO:0005618; GO:0005576; GO:0007275; GO:0005199,cell wall; extracellular region; multicellular organismal development; structural constituent of cell wall,PF02095;,,,,,,,,,PRP2_SOYBN,Glycine max (Soybean) (Glycine hispida),multicellular organism development [GO:0007275] comp126828_c0_seq1,3338,36.8185,0.62334987,13563,43877,,1.00E-160,P52193,Calreticulin (CRP55) (Calregulin) (HACBP),Calreticulin (CRP55) (Calregulin) (HACBP),GO:0005509; GO:0006457; GO:0050821; GO:0033018,calcium ion binding; protein folding; protein stabilization; sarcoplasmic reticulum lumen,PF00262;,0,CHOYP_LOC100533294.1.3,5.00E-56,ruditapes2_c1323,,,,,CALR_BOVIN,Bos taurus (Bovine),protein folding [GO:0006457]; protein stabilization [GO:0050821] comp126834_c1_seq1,1124,39.1459,0.53167536,37,149,,2.00E-08,Q0P4A6,Protein TSSC4,Protein TSSC4,GO:0072113,head kidney development,PF15264;,,,,,,,,,TSSC4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126837_c0_seq1,586,29.0102,0.40645458,97,8,,,,,,,,,,,1.00E-15,ruditapes_c14730,,,,,,, comp126846_c0_seq1,330,37.5758,0.9146257,7,41,,2.00E-07,Q9H254,"Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)","Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)",GO:0016605; GO:0003779; GO:0051693; GO:0005912; GO:0007628; GO:0030506; GO:0007411; GO:0043203; GO:0043194; GO:0061337; GO:0070852; GO:0021952; GO:0045162; GO:0007016; GO:0005829; GO:0090002; GO:0009566; GO:0010459; GO:0033268; GO:0016363; GO:0033270; GO:0005543; GO:0005886; GO:0040018; GO:0033135; GO:0002028; GO:0007605; GO:0008091; GO:0030507; GO:0005200; GO:0019226; GO:0016192,PML body; actin binding; actin filament capping; adherens junction; adult walking behavior; ankyrin binding; axon guidance; axon hillock; axon initial segment; cardiac conduction; cell body fiber; central nervous system projection neuron axonogenesis; clustering of voltage-gated sodium channels; cytoskeletal anchoring at plasma membrane; cytosol; establishment of protein localization to plasma membrane; fertilization; negative regulation of heart rate; node of Ranvier; nuclear matrix; paranode region of axon; phospholipid binding; plasma membrane; positive regulation of multicellular organism growth; regulation of peptidyl-serine phosphorylation; regulation of sodium ion transport; sensory perception of sound; spectrin; spectrin binding; structural constituent of cytoskeleton; transmission of nerve impulse; vesicle-mediated transport,PF00307;PF00435;,,,,,,,,,SPTN4_HUMAN,Homo sapiens (Human),actin filament capping [GO:0051693]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cardiac conduction [GO:0061337]; central nervous system projection neuron axonogenesis [GO:0021952]; clustering of voltage-gated sodium channels [GO:0045162]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization to plasma membrane [GO:0090002]; fertilization [GO:0009566]; MAPK cascade [GO:0000165]; negative regulation of heart rate [GO:0010459]; positive regulation of multicellular organism growth [GO:0040018]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of sodium ion transport [GO:0002028]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226]; vesicle-mediated transport [GO:0016192] comp126846_c1_seq1,591,43.824,0.49885781,4,41,,6.00E-70,P13796,Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1),Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1),GO:0002286; GO:0003779; GO:0015629; GO:0005884; GO:0051017; GO:0005509; GO:0030054; GO:0005829; GO:0031100; GO:0001891; GO:0005886; GO:0033157; GO:0032587,T cell activation involved in immune response; actin binding; actin cytoskeleton; actin filament; actin filament bundle assembly; calcium ion binding; cell junction; cytosol; organ regeneration; phagocytic cup; plasma membrane; regulation of intracellular protein transport; ruffle membrane,PF00307;PF13499;,2.00E-35,CHOYP_PHUM_PHUM267720.2.2,,,,,,,PLSL_HUMAN,Homo sapiens (Human),actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; organ regeneration [GO:0031100]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; T cell activation involved in immune response [GO:0002286] comp126850_c0_seq1,799,39.7997,0.60413449,1,896,female>male,2.00E-10,Q8BYF6,Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8),Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8),GO:0016324; GO:0006915; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; apoptotic process; integral to membrane; sodium ion transport; symporter activity,PF00474;,1.00E-13,CHOYP_BRAFLDRAFT_202614.1.1,,,,,,,SC5A8_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; sodium ion transport [GO:0006814] comp126851_c0_seq1,715,35.6643,0.80049846,161,964,,4.00E-23,Q0II25,Ribonuclease P protein subunit p20 (RNaseP protein p20) (EC 3.1.26.5),Ribonuclease P protein subunit p20 (RNaseP protein p20) (EC 3.1.26.5),GO:0005730; GO:0004526; GO:0008033,nucleolus; ribonuclease P activity; tRNA processing,PF12328;,,,,,,,,,POP7_BOVIN,Bos taurus (Bovine),"RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA processing [GO:0008033]" comp126856_c1_seq1,529,44.2344,0.51552747,29,44,,2.00E-80,Q9Y6D6,Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1),Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1),GO:0005086; GO:0000139; GO:0007030; GO:0005829; GO:0010256; GO:0006887; GO:0034259; GO:0030837; GO:0016363; GO:0005730; GO:0048471; GO:0090284; GO:0090303; GO:0034237; GO:0015031; GO:0032012; GO:2000114; GO:0030532; GO:0005802,ARF guanyl-nucleotide exchange factor activity; Golgi membrane; Golgi organization; cytosol; endomembrane system organization; exocytosis; negative regulation of Rho GTPase activity; negative regulation of actin filament polymerization; nuclear matrix; nucleolus; perinuclear region of cytoplasm; positive regulation of protein glycosylation in Golgi; positive regulation of wound healing; protein kinase A regulatory subunit binding; protein transport; regulation of ARF protein signal transduction; regulation of establishment of cell polarity; small nuclear ribonucleoprotein complex; trans-Golgi network,PF16213;PF09324;PF01369;PF12783;,3.00E-77,CHOYP_BIG1.3.3,,,,,,,BIG1_HUMAN,Homo sapiens (Human),endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; neuron projection development [GO:0031175]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114] comp126862_c0_seq4,860,42.4419,0.39179157,12,19,,5.00E-28,Q1RM35,Coiled-coil domain-containing protein 104,Cilia- and flagella-associated protein 36 (Coiled-coil domain-containing protein 104),,,PF11527;,,,,,,,,,CC104_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126863_c0_seq1,1255,42.2311,0.3766442,19,37,,2.00E-118,P49916,DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006284; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0043504; GO:0045910; GO:0005654; GO:0006289; GO:0007131; GO:0007283; GO:0000795; GO:0008270,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; base-excision repair; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; mitochondrial DNA repair; negative regulation of DNA recombination; nucleoplasm; nucleotide-excision repair; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex; zinc ion binding,PF04679;PF01068;PF04675;PF16759;PF00645;,2.00E-77,CHOYP_BRAFLDRAFT_119901.1.1,,,,,,,DNLI3_HUMAN,Homo sapiens (Human),"base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp126863_c1_seq1,212,38.2075,0.27168972,1,22,,2.00E-07,P49916,DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006284; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0043504; GO:0045910; GO:0005654; GO:0006289; GO:0007131; GO:0007283; GO:0000795; GO:0008270,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; base-excision repair; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; mitochondrial DNA repair; negative regulation of DNA recombination; nucleoplasm; nucleotide-excision repair; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex; zinc ion binding,PF04679;PF01068;PF04675;PF16759;PF00645;,,,6.00E-15,ruditapes_c24785,,,,,DNLI3_HUMAN,Homo sapiens (Human),"base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp126865_c0_seq1,846,46.3357,0.53003829,35,7,,4.00E-102,Q8N2C7,Protein unc-80 homolog,Protein unc-80 homolog,GO:0016021; GO:0034220; GO:0005886,integral to membrane; ion transmembrane transport; plasma membrane,PF15778;,8.00E-137,CHOYP_PHUM_PHUM244880.1.2,,,,,,,UNC80_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220] comp126870_c0_seq1,585,32.4786,1.13204876,13,13,,,,,,,,,,,1.00E-29,ruditapes_c7166,,,,,,, comp126870_c0_seq2,586,32.9352,1.21811189,0,0,,6.00E-06,Q09345,Polyadenylation and cleavage factor homolog 11,Polyadenylation and cleavage factor homolog 11,,,PF04818;,,,,,,,,,PCF11_CAEEL,Caenorhabditis elegans,mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369] comp126877_c0_seq1,1107,49.0515,0.51107053,38,56,,1.00E-70,Q9C0C7,Activating molecule in BECN1-regulated autophagy protein 1,Activating molecule in BECN1-regulated autophagy protein 1,GO:0005776; GO:0006914; GO:0030154; GO:0005737; GO:0031410; GO:0008285; GO:0021915; GO:0043065,autophagic vacuole; autophagy; cell differentiation; cytoplasm; cytoplasmic vesicle; negative regulation of cell proliferation; neural tube development; positive regulation of apoptotic process,,9.00E-81,CHOYP_BRAFLDRAFT_126632.1.1,,,,,,,AMRA1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; parkin-mediated mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of mitophagy [GO:1903599]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of autophagosome assembly [GO:2000785] comp126879_c0_seq1,1305,38.6973,0.45067003,159,1156,,5.00E-67,Q9D7W5,Mediator of RNA polymerase II transcription subunit 8 (Activator-recruited cofactor 32 kDa component) (ARC32) (Mediator complex subunit 8),Mediator of RNA polymerase II transcription subunit 8 (Activator-recruited cofactor 32 kDa component) (ARC32) (Mediator complex subunit 8),GO:0001104; GO:0016592; GO:0016567,RNA polymerase II transcription cofactor activity; mediator complex; protein ubiquitination,PF10232;,3.00E-18,CHOYP_MED8B.1.1,,,,,,,MED8_MOUSE,Mus musculus (Mouse),"protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]" comp126886_c0_seq1,1305,44.4444,0.29646373,60,44,,5.00E-95,Q9BZH6,WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15),WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15),GO:0005929; GO:0016021; GO:0005765; GO:0005634,cilium; integral to membrane; lysosomal membrane; nucleus,,3.00E-37,CHOYP_WDR11.2.2,,,,,,,WDR11_HUMAN,Homo sapiens (Human), comp126889_c2_seq4,332,30.7229,0.38542016,8,58,,,,,,,,,,,2.00E-16,ruditapes_c17805,,,,,,, comp126900_c0_seq1,1035,34.0097,0.61764764,2029,5473,,1.00E-32,P0CB92,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (NADH-ubiquinone oxidoreductase 19 kDa subunit),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (NADH-ubiquinone oxidoreductase 19 kDa subunit),GO:0005758; GO:0055114; GO:0070469,mitochondrial intermembrane space; oxidation-reduction process; respiratory chain,PF06747;,,,,,,,,,NDUA8_PONPY,Pongo pygmaeus (Bornean orangutan),oxidation-reduction process [GO:0055114] comp126905_c1_seq1,1086,39.1344,0.76410496,62,71,,6.00E-41,O94966,Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9),Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9),GO:0030433; GO:0005829; GO:0005789; GO:0016021; GO:0046872; GO:0048642; GO:0090068; GO:0016579; GO:1900037; GO:0031647; GO:0034976; GO:0014732; GO:0004221; GO:0004843,ER-associated protein catabolic process; cytosol; endoplasmic reticulum membrane; integral to membrane; metal ion binding; negative regulation of skeletal muscle tissue development; positive regulation of cell cycle process; protein deubiquitination; regulation of cellular response to hypoxia; regulation of protein stability; response to endoplasmic reticulum stress; skeletal muscle atrophy; ubiquitin thiolesterase activity; ubiquitin-specific protease activity,PF04969;PF00443;PF01753;,3.00E-48,CHOYP_UBP19.1.1,,,,,,,UBP19_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976] comp126911_c0_seq1,1022,45.2055,0.75102949,67,87,,6.00E-37,Q9CW42,"MOSC domain-containing protein 1, mitochondrial (EC 1.-.-.-) (Mitochondrial amidoxime reducing component 1) (mARC1) (Moco sulfurase C-terminal domain-containing protein 1) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1)",Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1),GO:0016021; GO:0005743; GO:0005741; GO:0030151; GO:0016491; GO:0030170,integral to membrane; mitochondrial inner membrane; mitochondrial outer membrane; molybdenum ion binding; oxidoreductase activity; pyridoxal phosphate binding,PF03473;PF03476;,,,,,,,,,MOSC1_MOUSE,Mus musculus (Mouse),nitrate metabolic process [GO:0042126]; oxidation-reduction process [GO:0055114] comp126913_c0_seq1,1593,39.0458,0.64170718,6478,370830,,4.00E-45,P41311,Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II),Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II),GO:0005507; GO:0004129; GO:0022900; GO:0016021; GO:0005743; GO:0045277,copper ion binding; cytochrome-c oxidase activity; electron transport chain; integral to membrane; mitochondrial inner membrane; respiratory chain complex IV,PF00116;PF02790;,,,,,,,,,COX2_DIDVI,Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana),electron transport chain [GO:0022900] comp126914_c0_seq1,981,38.634,0.46430308,53,71,,,,,,,,,1.00E-22,CHOYP_LOC100184532.1.1,,,,,,,,, comp126923_c0_seq1,728,42.033,1.16343387,0,166,,4.00E-56,Q95NI4,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,3.00E-15,CHOYP_CALM.32.50,7.00E-21,ruditapes2_c4557,,,,,CALM_HALOK,Halichondria okadai (Marine sponge) (Reniera okadai), comp126925_c0_seq1,1457,37.2684,0.56000026,0,9,,2.00E-24,P14404,MDS1 and EVI1 complex locus protein EVI1 (Ecotropic virus integration site 1 protein) (EVI-1),MDS1 and EVI1 complex locus protein EVI1 (Ecotropic virus integration site 1 protein) (EVI-1),GO:0003677; GO:0006915; GO:0030154; GO:0035115; GO:0035116; GO:0030900; GO:0071425; GO:0001701; GO:0006954; GO:0046872; GO:0046329; GO:0043069; GO:0045892; GO:0001780; GO:0016607; GO:0060039; GO:0045944; GO:0009791; GO:0042803; GO:0051726; GO:0042127; GO:0072001; GO:0009617; GO:0003700; GO:0006351,"DNA binding; apoptotic process; cell differentiation; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; forebrain development; hematopoietic stem cell proliferation; in utero embryonic development; inflammatory response; metal ion binding; negative regulation of JNK cascade; negative regulation of programmed cell death; negative regulation of transcription, DNA-dependent; neutrophil homeostasis; nuclear speck; pericardium development; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein homodimerization activity; regulation of cell cycle; regulation of cell proliferation; renal system development; response to bacterium; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,EVI1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; forebrain development [GO:0030900]; hematopoietic stem cell proliferation [GO:0071425]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; maintenance of cell number [GO:0098727]; negative regulation of JNK cascade [GO:0046329]; negative regulation of programmed cell death [GO:0043069]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil homeostasis [GO:0001780]; pericardium development [GO:0060039]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of cell cycle [GO:0051726]; regulation of cell proliferation [GO:0042127]; renal system development [GO:0072001]; response to bacterium [GO:0009617]; transcription, DNA-templated [GO:0006351]" comp126925_c0_seq2,1381,37.7263,0.57619376,0,0,,4.00E-46,Q8N895,Zinc finger protein 366,Zinc finger protein 366,GO:0003677; GO:0030331; GO:0046872; GO:0033147; GO:0000122; GO:0005634; GO:0043627; GO:0003714; GO:0006351,"DNA binding; estrogen receptor binding; metal ion binding; negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; response to estrogen stimulus; transcription corepressor activity; transcription, DNA-dependent",PF00096;PF13912;,2.00E-45,CHOYP_ZNF366.1.1,2.00E-56,ruditapes_c29612,,,,,ZN366_HUMAN,Homo sapiens (Human),"negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]" comp126928_c0_seq1,339,40.118,0.62271604,0,0,,6.00E-11,Q5U538,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_XENLA,Xenopus laevis (African clawed frog), comp126928_c2_seq1,368,36.6848,0.57070682,14,12,,1.00E-14,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126928_c2_seq3,312,42.9487,0.64492421,4,13,,4.00E-13,B0BN95,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_RAT,Rattus norvegicus (Rat), comp126931_c0_seq5,1369,35.7925,0.66190226,10,9,,8.00E-89,Q6IQE9,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6),Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6),GO:0005737; GO:0046872; GO:0005634; GO:0016706,"cytoplasm; metal ion binding; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13532;,,,,,,,,,ALKB6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp126931_c0_seq6,686,39.7959,0.44294098,6,17,,,,,,,,,2.00E-36,CHOYP_LOC101061324.1.1,,,,,,,,, comp126941_c0_seq1,611,43.3715,0.42663063,35,42,,3.00E-68,Q6I6G8,"E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)","E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)",GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00168;PF00632;PF16562;PF00397;,1.00E-75,CHOYP_NEDD4L.1.1,,,,,,,HECW2_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp126941_c1_seq2,1030,43.1068,0.51078635,7,22,,3.00E-122,Q5RBF2,E3 ubiquitin-protein ligase NEDD4-like (EC 6.3.2.-),E3 ubiquitin-protein ligase NEDD4-like (EC 6.3.2.-),GO:0005737; GO:0004842,cytoplasm; ubiquitin-protein ligase activity,PF00168;PF00632;PF00397;,8.00E-100,CHOYP_NED4L.1.1,,,,,,,NED4L_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell differentiation [GO:0030154] comp126941_c1_seq3,930,42.5806,0.4343819,3,10,,7.00E-21,Q2EJA0,Yorkie homolog (65 kDa Yes-associated protein) (YAP65),Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog),GO:0006975; GO:0071480; GO:0005737; GO:0005634; GO:0006355; GO:0044212; GO:0006351,"DNA damage induced protein phosphorylation; cellular response to gamma radiation; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00397;,,,,,,,,,YAP1_RAT,Rattus norvegicus (Rat),"bud elongation involved in lung branching [GO:0060449]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; DNA damage induced protein phosphorylation [GO:0006975]; embryonic heart tube morphogenesis [GO:0003143]; hippo signaling [GO:0035329]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of stem cell differentiation [GO:2000737]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]" comp126941_c2_seq1,845,43.787,0.6009954,3,0,,5.00E-10,Q9SKR2,Synaptotagmin-1 (NTMC2T1.1) (Synaptotagmin A),Synaptotagmin-1 (NTMC2T1.1) (Synaptotagmin A),GO:0006897; GO:0010008; GO:0016021; GO:0008289; GO:0046872; GO:0019048; GO:0005886,endocytosis; endosome membrane; integral to membrane; lipid binding; metal ion binding; modulation by virus of host morphology or physiology; plasma membrane,PF00168;PF17047;,,,,,,,,,SYT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),endocytosis [GO:0006897]; viral process [GO:0016032] comp126941_c2_seq2,891,43.771,0.61707187,5,11,,1.00E-12,Q9R0N7,Synaptotagmin-7 (Synaptotagmin VII) (SytVII),Synaptotagmin-7 (Synaptotagmin VII) (SytVII),GO:0030054; GO:0016021; GO:0005764; GO:0046872; GO:0001778; GO:0030672; GO:0005215,cell junction; integral to membrane; lysosome; metal ion binding; plasma membrane repair; synaptic vesicle membrane; transporter activity,PF00168;,,,,,,,,,SYT7_MOUSE,Mus musculus (Mouse),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119] comp126944_c0_seq1,870,39.3103,0.44718706,10,98,,1.00E-30,Q9QXE5,Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16),Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16),GO:0016023; GO:0005768; GO:0005764; GO:0006508; GO:0008236,cytoplasmic membrane-bounded vesicle; endosome; lysosome; proteolysis; serine-type peptidase activity,PF05577;,,,,,,,,,TSSP_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp126953_c0_seq1,2159,35.7573,0.30593463,17008,100384,,9.00E-130,P81004,Voltage-dependent anion-selective channel protein 2 (VDAC-2) (Outer mitochondrial membrane protein porin),Voltage-dependent anion-selective channel protein 2 (VDAC-2) (Outer mitochondrial membrane protein porin),GO:0005741; GO:0000166; GO:0046930; GO:0015288; GO:0008308,mitochondrial outer membrane; nucleotide binding; pore complex; porin activity; voltage-gated anion channel activity,PF01459;,8.00E-66,CHOYP_VDAC2.1.2,5.00E-66,ruditapes_c19690,,,,,VDAC2_XENLA,Xenopus laevis (African clawed frog), comp126955_c0_seq1,259,44.4015,0.62916848,2,9,,1.00E-28,P55265,Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP),Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP),GO:0003677; GO:0003723; GO:0006382; GO:0005737; GO:0051607; GO:0003726; GO:0010467; GO:0031047; GO:0016556; GO:0006397; GO:0046872; GO:0043066; GO:0044387; GO:0005730; GO:0005654; GO:0005634; GO:0045070; GO:0006611; GO:0006606; GO:0035455; GO:0009615; GO:0044530; GO:0060337,DNA binding; RNA binding; adenosine to inosine editing; cytoplasm; defense response to virus; double-stranded RNA adenosine deaminase activity; gene expression; gene silencing by RNA; mRNA modification; mRNA processing; metal ion binding; negative regulation of apoptotic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; nucleoplasm; nucleus; positive regulation of viral genome replication; protein export from nucleus; protein import into nucleus; response to interferon-alpha; response to virus; supraspliceosomal complex; type I interferon-mediated signaling pathway,PF02137;PF00035;PF02295;,,,,,,,,,DSRAD_HUMAN,Homo sapiens (Human),adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337] comp126955_c0_seq2,758,43.5356,0.54114695,146,41,,3.00E-12,Q32NG0,Adenosine deaminase domain-containing protein 1,Adenosine deaminase domain-containing protein 1,GO:0003723; GO:0006396; GO:0004000; GO:0030154; GO:0007275; GO:0005634; GO:0007283,RNA binding; RNA processing; adenosine deaminase activity; cell differentiation; multicellular organismal development; nucleus; spermatogenesis,PF02137;PF00035;,,,,,,,,,ADAD1_XENLA,Xenopus laevis (African clawed frog),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283] comp126958_c0_seq1,1243,39.9839,0.52979559,727,7267,,6.00E-174,P52432,DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPC40),DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPC40),GO:0003677; GO:0005736; GO:0005666; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF01000;PF01193;,6.00E-103,CHOYP_RPAC1.1.1,1.00E-121,ruditapes_c24468,,,,,RPAC1_MOUSE,Mus musculus (Mouse),chromatin silencing at rDNA [GO:0000183]; piRNA metabolic process [GO:0034587]; transcription from RNA polymerase III promoter [GO:0006383]; transcription initiation from RNA polymerase I promoter [GO:0006361] comp126970_c0_seq3,1046,47.6099,0.42971867,0,0,,,,,,,,,3.00E-124,CHOYP_BRAFLDRAFT_69036.1.1,,,,,,,,, comp126982_c0_seq1,489,43.1493,0.44995597,38,20,,,,,,,,,2.00E-34,CHOYP_LOC100533357.1.2,,,,,,,,, comp126982_c1_seq1,662,46.9789,0.44433376,60,21,,6.00E-11,P34121,Coactosin (Cyclic AMP-regulated protein p16) (Cytoskeletal protein p17),Coactosin (Cyclic AMP-regulated protein p16) (Cytoskeletal protein p17),GO:0015629; GO:0051015; GO:0045335; GO:0030833; GO:0009617,actin cytoskeleton; actin filament binding; phagocytic vesicle; regulation of actin filament polymerization; response to bacterium,PF00241;,,,,,,,,,COAA_DICDI,Dictyostelium discoideum (Slime mold),regulation of actin filament polymerization [GO:0030833]; response to bacterium [GO:0009617] comp126989_c0_seq1,1599,39.0244,0.51804833,21,183,,6.00E-119,P08836,"Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)","Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)",GO:0006695; GO:0005737; GO:0004161; GO:0045337; GO:0033384; GO:0004337; GO:0046872,cholesterol biosynthetic process; cytoplasm; dimethylallyltranstransferase activity; farnesyl diphosphate biosynthetic process; geranyl diphosphate biosynthetic process; geranyltranstransferase activity; metal ion binding,PF00348;,7.00E-46,CHOYP_BRAFLDRAFT_123202.1.1,,,,,,,FPPS_CHICK,Gallus gallus (Chicken),cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384] comp126994_c1_seq2,1697,40.3654,0.49305756,65,316,,3.00E-114,Q6AYT0,Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin),Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin),GO:0070402; GO:0003960; GO:0005829; GO:0003730; GO:0051289; GO:0042178; GO:0008270,NADPH binding; NADPH:quinone reductase activity; cytosol; mRNA 3'-UTR binding; protein homotetramerization; xenobiotic catabolic process; zinc ion binding,PF08240;PF00107;,4.00E-30,CHOYP_CRYZ.2.2,,,,,,,QOR_RAT,Rattus norvegicus (Rat),protein homotetramerization [GO:0051289]; xenobiotic catabolic process [GO:0042178] comp126996_c0_seq1,520,45.5769,0.59928331,2,11,,2.00E-33,Q6NRV4,Retinol dehydrogenase 10-B (EC 1.1.1.300),Retinol dehydrogenase 10-B (EC 1.1.1.300),GO:0052650; GO:0005789; GO:0016021,NADP-retinol dehydrogenase activity; endoplasmic reticulum membrane; integral to membrane,PF00106;,1.00E-36,CHOYP_SDR16C5.1.1,,,,,,,RD10B_XENLA,Xenopus laevis (African clawed frog),retinoic acid biosynthetic process [GO:0002138] comp126996_c0_seq2,809,40.0494,0.52864024,27,18,,3.00E-38,A5PJJ7,Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-),Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-),GO:0016491,oxidoreductase activity,PF00106;,,,3.00E-51,ruditapes_c7765,,,,,S16C6_BOVIN,Bos taurus (Bovine), comp127008_c0_seq1,783,43.1673,0.25303968,17,22,,5.00E-73,P24802,"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)","Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)",GO:0031418; GO:0005506; GO:0008475; GO:0030867,L-ascorbic acid binding; iron ion binding; procollagen-lysine 5-dioxygenase activity; rough endoplasmic reticulum membrane,,6.00E-56,CHOYP_PLOD3.1.1,,,,,,,PLOD1_CHICK,Gallus gallus (Chicken), comp127008_c0_seq6,407,42.0147,0.11493027,0,0,,,,,,,,,2.00E-19,CHOYP_PLOD3.1.1,,,,,,,,, comp127011_c0_seq1,1497,43.9546,0.67754094,37,291,,2.00E-32,Q8VHG2,Angiomotin,Angiomotin,GO:0008180; GO:0030036; GO:0005884; GO:0043532; GO:0043534; GO:0042074; GO:0034613; GO:0006935; GO:0031410; GO:0030139; GO:0003365; GO:0009897; GO:0001702; GO:0035329; GO:0001701; GO:0016021; GO:0030027; GO:0034260; GO:0016525; GO:0043116; GO:0043536; GO:0040019; GO:0004872; GO:0051056; GO:0001726; GO:0001725; GO:0005923; GO:0001570,COP9 signalosome; actin cytoskeleton organization; actin filament; angiostatin binding; blood vessel endothelial cell migration; cell migration involved in gastrulation; cellular protein localization; chemotaxis; cytoplasmic vesicle; endocytic vesicle; establishment of cell polarity involved in ameboidal cell migration; external side of plasma membrane; gastrulation with mouth forming second; hippo signaling cascade; in utero embryonic development; integral to membrane; lamellipodium; negative regulation of GTPase activity; negative regulation of angiogenesis; negative regulation of vascular permeability; positive regulation of blood vessel endothelial cell migration; positive regulation of embryonic development; receptor activity; regulation of small GTPase mediated signal transduction; ruffle; stress fiber; tight junction; vasculogenesis,PF12240;,,,,,,,,,AMOT_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; blood vessel endothelial cell migration [GO:0043534]; blood vessel morphogenesis [GO:0048514]; cell migration involved in gastrulation [GO:0042074]; cellular protein localization [GO:0034613]; chemotaxis [GO:0006935]; establishment of cell polarity involved in ameboidal cell migration [GO:0003365]; gastrulation with mouth forming second [GO:0001702]; hippo signaling [GO:0035329]; in utero embryonic development [GO:0001701]; negative regulation of angiogenesis [GO:0016525]; negative regulation of GTPase activity [GO:0034260]; negative regulation of vascular permeability [GO:0043116]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of embryonic development [GO:0040019]; regulation of cell migration [GO:0030334]; regulation of small GTPase mediated signal transduction [GO:0051056]; vasculogenesis [GO:0001570] comp127012_c0_seq1,637,35.9498,0.48934006,420,351,,1.00E-42,Q6P026,Barrier-to-autointegration factor,Barrier-to-autointegration factor,GO:0003677; GO:0005694; GO:0005634,DNA binding; chromosome; nucleus,PF02961;,4.00E-32,CHOYP_LOC101161823.2.2,,,,,,,BAF_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp127021_c0_seq1,1602,39.0762,0.67308132,20,9,,2.00E-49,Q9JKK0,Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3) (Regulator of calcineurin 3),Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3) (Regulator of calcineurin 3),GO:0019722; GO:0000166,calcium-mediated signaling; nucleotide binding,PF04847;,8.00E-20,CHOYP_LOC100902369.2.2,,,,,,,RCAN3_MOUSE,Mus musculus (Mouse),calcium-mediated signaling [GO:0019722]; regulation of calcineurin-NFAT signaling cascade [GO:0070884] comp127021_c0_seq2,1428,39.4258,0.65143757,4,0,,,,,,,,,1.00E-17,CHOYP_LOC100902369.2.2,,,,,,,,, comp127023_c0_seq1,738,41.4634,0.57452703,61452,127949,,9.00E-67,P62282,40S ribosomal protein S11,40S ribosomal protein S11,GO:0022627; GO:0019843; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; rRNA binding; structural constituent of ribosome; translation,PF00366;PF16205;,3.00E-71,CHOYP_RPS11.5.5,1.00E-113,ruditapes_lrc32677,,,,,RS11_RAT,Rattus norvegicus (Rat),osteoblast differentiation [GO:0001649]; translation [GO:0006412] comp127024_c0_seq1,1396,36.533,0.2390041,71,232,,7.00E-30,Q6PHG8,DNA-directed RNA polymerase I subunit RPA43 (Twist neighbor protein),DNA-directed RNA polymerase I subunit RPA43 (Twist neighbor protein),GO:0003899; GO:0005730; GO:0006351,"DNA-directed RNA polymerase activity; nucleolus; transcription, DNA-dependent",PF03876;,,,,,,,,,RPA43_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),transcription from RNA polymerase I promoter [GO:0006360] comp127032_c1_seq2,633,43.2859,0.78196248,5,18,,2.00E-79,O15033,Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-),Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-),GO:0006915; GO:0005829; GO:0016021; GO:0043066; GO:0005634; GO:0042787; GO:0004842,apoptotic process; cytosol; integral to membrane; negative regulation of apoptotic process; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00630;PF00632;,,,,,,,,,K0317_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp127032_c2_seq1,283,43.8163,0.29934498,9,12,,3.00E-27,O15033,Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-),Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-),GO:0006915; GO:0005829; GO:0016021; GO:0043066; GO:0005634; GO:0042787; GO:0004842,apoptotic process; cytosol; integral to membrane; negative regulation of apoptotic process; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00630;PF00632;,1.00E-27,CHOYP_CG4238.1.1,,,,,,,K0317_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp127047_c0_seq1,833,44.4178,0.87889825,16,152,,5.00E-32,Q02338,"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase)","D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)",GO:0003858; GO:0060612; GO:0007420; GO:0044255; GO:0046951; GO:0046952; GO:0001889; GO:0005743; GO:0005759; GO:0005634; GO:0005543; GO:0046686; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0060416; GO:0032868; GO:0007584; GO:0042594; GO:0009636,3-hydroxybutyrate dehydrogenase activity; adipose tissue development; brain development; cellular lipid metabolic process; ketone body biosynthetic process; ketone body catabolic process; liver development; mitochondrial inner membrane; mitochondrial matrix; nucleus; phospholipid binding; response to cadmium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to growth hormone stimulus; response to insulin stimulus; response to nutrient; response to starvation; response to toxic substance,PF00106;,,,,,,,,,BDH_HUMAN,Homo sapiens (Human),adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636] comp127048_c0_seq1,461,30.8026,0.27631709,9,80,,,,,,,,,,,1.00E-21,ruditapes_c27344,,,,,,, comp127049_c0_seq1,1032,42.6357,0.45406636,55,57,,1.00E-116,Q04656,Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein),Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein),GO:0005524; GO:0042093; GO:0016323; GO:0001568; GO:0001974; GO:0031526; GO:0051216; GO:0006878; GO:0021702; GO:0030199; GO:0015677; GO:0004008; GO:0005829; GO:0048813; GO:0010273; GO:0042417; GO:0048251; GO:0051542; GO:0005783; GO:0042414; GO:0031069; GO:0001701; GO:0016021; GO:0005770; GO:0007626; GO:0048286; GO:0007005; GO:0048553; GO:0043524; GO:0043005; GO:0048812; GO:0043025; GO:0042421; GO:0042415; GO:0018205; GO:0048471; GO:0043473; GO:0048554; GO:0051353; GO:0021860; GO:0010468; GO:0002082; GO:0001836; GO:0019430; GO:0010041; GO:0010043; GO:0030141; GO:0042428; GO:0016532; GO:0005802; GO:0030140; GO:0006568; GO:0006570,ATP binding; T-helper cell differentiation; basolateral plasma membrane; blood vessel development; blood vessel remodeling; brush border membrane; cartilage development; cellular copper ion homeostasis; cerebellar Purkinje cell differentiation; collagen fibril organization; copper ion import; copper-exporting ATPase activity; cytosol; dendrite morphogenesis; detoxification of copper ion; dopamine metabolic process; elastic fiber assembly; elastin biosynthetic process; endoplasmic reticulum; epinephrine metabolic process; hair follicle morphogenesis; in utero embryonic development; integral to membrane; late endosome; locomotory behavior; lung alveolus development; mitochondrion organization; negative regulation of metalloenzyme activity; negative regulation of neuron apoptotic process; neuron projection; neuron projection morphogenesis; neuronal cell body; norepinephrine biosynthetic process; norepinephrine metabolic process; peptidyl-lysine modification; perinuclear region of cytoplasm; pigmentation; positive regulation of metalloenzyme activity; positive regulation of oxidoreductase activity; pyramidal neuron development; regulation of gene expression; regulation of oxidative phosphorylation; release of cytochrome c from mitochondria; removal of superoxide radicals; response to iron(III) ion; response to zinc ion; secretory granule; serotonin metabolic process; superoxide dismutase copper chaperone activity; trans-Golgi network; trans-Golgi network transport vesicle; tryptophan metabolic process; tyrosine metabolic process,PF00122;PF00403;,2.00E-69,CHOYP_ATP7A.1.1,,,,,,,ATP7A_HUMAN,Homo sapiens (Human),blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; plasma membrane copper ion transport [GO:0015679]; positive regulation of catalytic activity [GO:0043085]; positive regulation of oxidoreductase activity [GO:0051353]; pyramidal neuron development [GO:0021860]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] comp127050_c0_seq2,742,39.2183,0.38808238,24,66,,,,,,,,,2.00E-73,CHOYP_LOC100373488.1.1,,,,,,,,, comp127056_c0_seq1,837,41.0992,0.46221798,0,0,,2.00E-45,P73467,Epimerase family protein slr1223,Epimerase family protein slr1223,GO:0003824; GO:0044237; GO:0050662,catalytic activity; cellular metabolic process; coenzyme binding,PF08338;PF01370;,,,,,,,,,Y1223_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa), comp127056_c0_seq2,978,42.4335,0.50852393,0,0,,4.00E-81,Q17QH8,Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1),Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1),GO:0016491,oxidoreductase activity,PF08338;PF01370;,,,,,,,,,D39U1_BOVIN,Bos taurus (Bovine), comp127058_c0_seq1,1372,43.8047,0.44389098,88,121,,3.00E-84,Q5UAK0,Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1),Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1),GO:0003677; GO:0003682; GO:0031937; GO:0006351; GO:0017053,"DNA binding; chromatin binding; positive regulation of chromatin silencing; transcription, DNA-dependent; transcriptional repressor complex",PF01448;PF00249;,4.00E-130,CHOYP_PHUM_PHUM361660.1.1,,,,,,,MIER1_MOUSE,Mus musculus (Mouse),"positive regulation of chromatin silencing [GO:0031937]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transcription, DNA-templated [GO:0006351]" comp127061_c0_seq1,611,35.8429,0.49801218,5,25,,5.00E-17,Q9CXP9,Exonuclease V (Exo V) (mExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog),Exonuclease V (Exo V) (mExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog),GO:0051539; GO:0003677; GO:0005829; GO:0036297; GO:0046872; GO:0005634; GO:0045145,"4 iron, 4 sulfur cluster binding; DNA binding; cytosol; interstrand cross-link repair; metal ion binding; nucleus; single-stranded DNA 5'-3' exodeoxyribonuclease activity",PF09810;,,,,,,,,,EXO5_MOUSE,Mus musculus (Mouse),interstrand cross-link repair [GO:0036297] comp127061_c0_seq2,507,36.4892,0.71641304,0,7,,1.00E-09,Q9CXP9,Exonuclease V (Exo V) (mExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog),Exonuclease V (Exo V) (mExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog),GO:0051539; GO:0003677; GO:0005829; GO:0036297; GO:0046872; GO:0005634; GO:0045145,"4 iron, 4 sulfur cluster binding; DNA binding; cytosol; interstrand cross-link repair; metal ion binding; nucleus; single-stranded DNA 5'-3' exodeoxyribonuclease activity",PF09810;,,,,,,,,,EXO5_MOUSE,Mus musculus (Mouse),interstrand cross-link repair [GO:0036297] comp127063_c0_seq1,1327,39.1861,0.94975917,48,289,,6.00E-26,P13055,"Ecdysone-induced protein 75B, isoform B (E75-C) (Nuclear receptor subfamily 1 group D member 3, isoform B)","Ecdysone-induced protein 75B, isoform B (E75-C) (Nuclear receptor subfamily 1 group D member 3, isoform B)",GO:0003677; GO:0019730; GO:0018990; GO:0035072; GO:0020037; GO:0004879; GO:0005634; GO:0048477; GO:0007553; GO:0043565; GO:0003707; GO:0004887; GO:0008270,"DNA binding; antimicrobial humoral response; ecdysis, chitin-based cuticle; ecdysone-mediated induction of salivary gland cell autophagic cell death; heme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; oogenesis; regulation of ecdysteroid metabolic process; sequence-specific DNA binding; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,,,,,,,,,E75BB_DROME,Drosophila melanogaster (Fruit fly),"antimicrobial humoral response [GO:0019730]; ecdysis, chitin-based cuticle [GO:0018990]; molting cycle, chitin-based cuticle [GO:0007591]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; regulation of ecdysteroid metabolic process [GO:0007553]; regulation of gene expression [GO:0010468]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; response to ecdysone [GO:0035075]; transcription, DNA-templated [GO:0006351]" comp127064_c0_seq2,516,43.9922,0.32439338,3,0,,3.00E-61,Q91YK0,Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79),Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79),GO:0005737; GO:0005874,cytoplasm; microtubule,,1.00E-82,CHOYP_BRAFLDRAFT_67566.2.4,,,,,,,LRC49_MOUSE,Mus musculus (Mouse), comp127064_c0_seq3,1011,44.7082,0.63414792,23,5,,,,,,,,,1.00E-90,CHOYP_BRAFLDRAFT_67566.4.4,,,,,,,,, comp127066_c0_seq1,994,37.7264,0.48949581,105,146,,3.00E-64,Q9Y6F1,Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3),Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3),GO:0006281; GO:0003950; GO:0003824; GO:0005814; GO:0005634; GO:0006471,DNA repair; NAD+ ADP-ribosyltransferase activity; catalytic activity; centriole; nucleus; protein ADP-ribosylation,PF00644;PF02877;PF05406;,7.00E-31,CHOYP_BRAFLDRAFT_203655.2.2,,,,,,,PARP3_HUMAN,Homo sapiens (Human),DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; lagging strand elongation [GO:0006273]; positive regulation of DNA ligation [GO:0051106]; protein ADP-ribosylation [GO:0006471]; protein localization to site of double-strand break [GO:1990166]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723] comp127071_c0_seq1,221,49.7738,0.32877385,17,49,,3.00E-06,Q01456,Ovarian abundant message protein (Protein OAM),Ovarian abundant message protein (Protein OAM),,,,,,,,,,,,OAM_ASCSU,Ascaris suum (Pig roundworm) (Ascaris lumbricoides), comp127076_c0_seq1,869,38.8953,0.79986867,15,89,,4.00E-141,Q16932,Syntaxin,Syntaxin,GO:0016021; GO:0006886; GO:0006836; GO:0016192,integral to membrane; intracellular protein transport; neurotransmitter transport; vesicle-mediated transport,PF05739;PF00804;,8.00E-156,CHOYP_STX.1.1,,,,,,,STX_APLCA,Aplysia californica (California sea hare),intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter transport [GO:0006836]; regulation of exocytosis [GO:0017157]; vesicle-mediated transport [GO:0016192] comp127090_c0_seq1,3402,39.3592,0.97990365,1435,6899,,5.00E-49,Q13887,Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2),Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2),GO:0003677; GO:0005794; GO:0001525; GO:0046872; GO:0030033; GO:0005634; GO:0045893; GO:0003700; GO:0035914; GO:0006366,"DNA binding; Golgi apparatus; angiogenesis; metal ion binding; microvillus assembly; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription from RNA polymerase II promoter",PF00096;,8.00E-81,CHOYP_EF1A.4.4,,,4.00E-80,DW713853.p.cg.6,1,,KLF5_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of microvillus assembly [GO:0032534]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366] comp127093_c0_seq1,892,42.8251,0.3539141,47,112,,9.00E-87,Q8BH24,Transmembrane 9 superfamily member 4,Transmembrane 9 superfamily member 4,GO:0016021,integral to membrane,PF02990;,4.00E-71,CHOYP_TM9S4.1.1,,,,,,,TM9S4_MOUSE,Mus musculus (Mouse), comp127098_c1_seq1,1944,44.7531,0.37231026,56,50,,5.00E-09,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp127098_c2_seq2,1838,45.049,0.45101968,0,0,,9.00E-158,Q8K4Q0,Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein),Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein),GO:0031929; GO:0031931; GO:0016049; GO:0071230; GO:0005764; GO:0032008,TOR signaling cascade; TORC1 complex; cell growth; cellular response to amino acid stimulus; lysosome; positive regulation of TOR signaling cascade,PF02985;PF14538;PF00400;,0,CHOYP_RPTOR.1.1,,,,,,,RPTOR_MOUSE,Mus musculus (Mouse),cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nutrient levels [GO:0031669]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; regulation of cell size [GO:0008361]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp127098_c2_seq3,1871,45.163,0.44090544,0,0,,7.00E-93,Q93YQ1,Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b),Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b),GO:0080008; GO:0031929; GO:0031931; GO:0016049; GO:0009793; GO:0040008,Cul4-RING ubiquitin ligase complex; TOR signaling cascade; TORC1 complex; cell growth; embryo development ending in seed dormancy; regulation of growth,PF14538;,,,,,,,,,RTOR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell growth [GO:0016049]; embryo development ending in seed dormancy [GO:0009793]; regulation of growth [GO:0040008]; TOR signaling [GO:0031929] comp127098_c2_seq4,1208,44.2053,0.41372849,0,0,,8.00E-120,Q55BR7,Protein raptor homolog,Protein raptor homolog,GO:0031929; GO:0031931; GO:0008284,TOR signaling cascade; TORC1 complex; positive regulation of cell proliferation,PF14538;,4.00E-117,CHOYP_RPTOR.1.1,,,,,,,RPTOR_DICDI,Dictyostelium discoideum (Slime mold),positive regulation of asexual reproduction [GO:1903666]; TOR signaling [GO:0031929] comp127098_c2_seq5,1241,44.3997,0.39935717,0,0,,1.00E-95,Q93YQ1,Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b),Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b),GO:0080008; GO:0031929; GO:0031931; GO:0016049; GO:0009793; GO:0040008,Cul4-RING ubiquitin ligase complex; TOR signaling cascade; TORC1 complex; cell growth; embryo development ending in seed dormancy; regulation of growth,PF14538;,,,,,,,,,RTOR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell growth [GO:0016049]; embryo development ending in seed dormancy [GO:0009793]; regulation of growth [GO:0040008]; TOR signaling [GO:0031929] comp127098_c2_seq6,1328,47.1386,0.45009262,0,0,,1.00E-161,Q8K4Q0,Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein),Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein),GO:0031929; GO:0031931; GO:0016049; GO:0071230; GO:0005764; GO:0032008,TOR signaling cascade; TORC1 complex; cell growth; cellular response to amino acid stimulus; lysosome; positive regulation of TOR signaling cascade,PF02985;PF14538;PF00400;,,,,,,,,,RPTOR_MOUSE,Mus musculus (Mouse),cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nutrient levels [GO:0031669]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; regulation of cell size [GO:0008361]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp127098_c2_seq9,1958,46.9867,0.47216209,0,0,,8.00E-58,P38873,Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24),Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24),GO:0031929; GO:0031931; GO:0009267; GO:0000329; GO:0005886; GO:0001558; GO:0043130,TOR signaling cascade; TORC1 complex; cellular response to starvation; fungal-type vacuole membrane; plasma membrane; regulation of cell growth; ubiquitin binding,PF02985;PF14538;,,,,,,,,,KOG1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to starvation [GO:0009267]; regulation of cell growth [GO:0001558]; TOR signaling [GO:0031929] comp127099_c0_seq1,667,35.3823,0.43628545,6899,22728,,3.00E-16,Q9CPQ8,"ATP synthase subunit g, mitochondrial (ATPase subunit g)","ATP synthase subunit g, mitochondrial (ATPase subunit g)",GO:0015986; GO:0015078; GO:0005753; GO:0000276,"ATP synthesis coupled proton transport; hydrogen ion transmembrane transporter activity; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",PF04718;,,,,,,,,,ATP5L_MOUSE,Mus musculus (Mouse),ATP synthesis coupled proton transport [GO:0015986] comp127102_c0_seq2,593,35.2445,0.60332582,1,12,,7.00E-11,Q6ICL3,Transport and Golgi organization protein 2 homolog,Transport and Golgi organization protein 2 homolog,GO:0005739,mitochondrion,PF05742;,,,,,,,,,CV025_HUMAN,Homo sapiens (Human), comp127103_c0_seq1,999,36.9369,0.73468982,11,264,,2.00E-25,Q9UIL1,Short coiled-coil protein,Short coiled-coil protein,GO:0000139; GO:0005829; GO:0016239,Golgi membrane; cytosol; positive regulation of macroautophagy,PF10224;,3.00E-41,CHOYP_PHUM_PHUM574550.1.1,,,,,,,SCOC_HUMAN,Homo sapiens (Human),positive regulation of macroautophagy [GO:0016239]; regulation of protein complex stability [GO:0061635] comp127104_c0_seq1,275,40.3636,0.46154456,1,3,,5.00E-12,E7F6F9,Kelch-like protein 3,Kelch-like protein 3,GO:0031463; GO:0005856; GO:0005829; GO:0072156; GO:0050801; GO:0070936; GO:0042787; GO:0070294,Cul3-RING ubiquitin ligase complex; cytoskeleton; cytosol; distal tubule morphogenesis; ion homeostasis; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; renal sodium ion absorption,PF07707;PF00651;PF01344;,,,,,,,,,KLHL3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294] comp127104_c1_seq1,1046,40.153,0.61951253,32,65,,8.00E-22,Q9CZ49,Kelch-like protein 35,Kelch-like protein 35,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH35_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp127108_c0_seq1,544,47.0588,0.50144315,66300,199358,,1.00E-69,P60868,40S ribosomal protein S20,40S ribosomal protein S20,GO:0003723; GO:0022627; GO:0003735; GO:0006412,RNA binding; cytosolic small ribosomal subunit; structural constituent of ribosome; translation,PF00338;,2.00E-116,CHOYP_TM9S4.1.1,1.00E-135,ruditapes_lrc34105,,,,,RS20_RAT,Rattus norvegicus (Rat),translation [GO:0006412] comp127111_c0_seq1,392,45.9184,0.48346405,23,77,,4.00E-49,P46662,Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin),Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin),GO:0014010; GO:0030036; GO:0005912; GO:0045216; GO:0032154; GO:0030864; GO:0005769; GO:0007398; GO:0019898; GO:0030175; GO:0030027; GO:0070306; GO:0001707; GO:0008156; GO:0043409; GO:0008285; GO:0022408; GO:0006469; GO:0042518; GO:0042524; GO:0005730; GO:0005634; GO:0042475; GO:0048471; GO:0005886; GO:0051496; GO:0035330; GO:0001726,Schwann cell proliferation; actin cytoskeleton organization; adherens junction; cell-cell junction organization; cleavage furrow; cortical actin cytoskeleton; early endosome; ectoderm development; extrinsic to membrane; filopodium; lamellipodium; lens fiber cell differentiation; mesoderm formation; negative regulation of DNA replication; negative regulation of MAPK cascade; negative regulation of cell proliferation; negative regulation of cell-cell adhesion; negative regulation of protein kinase activity; negative regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of tyrosine phosphorylation of Stat5 protein; nucleolus; nucleus; odontogenesis of dentin-containing tooth; perinuclear region of cytoplasm; plasma membrane; positive regulation of stress fiber assembly; regulation of hippo signaling cascade; ruffle,PF00769;PF09380;PF00373;PF09379;,3.00E-50,CHOYP_MERL.1.1,,,,,,,MERL_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010] comp127116_c0_seq2,1200,39.9167,0.86753055,5,668,female>male,1.00E-70,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,5.00E-27,CHOYP_LOC100369190.1.1,3.00E-27,ruditapes2_c791,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp127130_c0_seq3,624,42.1474,0.6506668,0,12,,5.00E-44,Q27955,Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2),Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2),GO:0005737; GO:0016021; GO:0044224; GO:0005249,cytoplasm; integral to membrane; juxtaparanode region of axon; voltage-gated potassium channel activity,PF00248;,3.00E-46,CHOYP_BRAFLDRAFT_67317.2.2,,,,,,,KCAB2_BOVIN,Bos taurus (Bovine),hematopoietic progenitor cell differentiation [GO:0002244]; NADPH oxidation [GO:0070995]; neuromuscular process [GO:0050905]; oxidation-reduction process [GO:0055114]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008] comp127138_c0_seq2,1611,36.8094,0.36904776,95,77,,2.00E-11,P38766,ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (Regulation of Ty1 transposition protein 104) (rDNA recombination mutation protein 3),ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (Regulation of Ty1 transposition protein 104) (rDNA recombination mutation protein 3),GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0006260; GO:0000002; GO:0005724; GO:0005657; GO:0097046; GO:0000723,ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; DNA replication; mitochondrial genome maintenance; nuclear telomeric heterochromatin; replication fork; replication fork progression beyond termination site; telomere maintenance,PF05970;,,,,,,,,,RRM3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),DNA repair [GO:0006281]; DNA replication [GO:0006260]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; replication fork progression beyond termination site [GO:0097046]; replication fork reversal [GO:0071932]; telomere maintenance [GO:0000723] comp127149_c0_seq1,912,41.6667,0.43383885,0,0,,6.00E-118,A5D979,SprT-like domain-containing protein Spartan (Protein with SprT-like domain at the N terminus) (Spartan),SprT-like domain-containing protein Spartan (Protein with SprT-like domain at the N terminus) (Spartan),GO:0003677; GO:0070530; GO:0006556; GO:0005694; GO:0046872; GO:0004478; GO:0016607; GO:0005634; GO:0031398; GO:0009411; GO:0019985,DNA binding; K63-linked polyubiquitin binding; S-adenosylmethionine biosynthetic process; chromosome; metal ion binding; methionine adenosyltransferase activity; nuclear speck; nucleus; positive regulation of protein ubiquitination; response to UV; translesion synthesis,PF10263;,4.00E-84,CHOYP_C14H1ORF124.1.1,,,,,,,SPRTN_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein ubiquitination [GO:0031398]; response to UV [GO:0009411]; S-adenosylmethionine biosynthetic process [GO:0006556]; translesion synthesis [GO:0019985] comp127149_c0_seq2,1911,38.0429,0.32018033,10,106,,6.00E-112,D3ZVU1,SprT-like domain-containing protein Spartan (Protein with SprT-like domain at the N terminus) (Spartan),SprT-like domain-containing protein Spartan (Protein with SprT-like domain at the N terminus) (Spartan),GO:0003677; GO:0070530; GO:0005694; GO:0046872; GO:0005634; GO:0031398; GO:0009411; GO:0019985,DNA binding; K63-linked polyubiquitin binding; chromosome; metal ion binding; nucleus; positive regulation of protein ubiquitination; response to UV; translesion synthesis,PF10263;,,,,,,,,,SPRTN_RAT,Rattus norvegicus (Rat),cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein ubiquitination [GO:0031398]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp127150_c0_seq4,819,41.0256,0.34799435,0,0,,4.00E-06,Q95PA1,Complexin (Synaphin),Complexin (Synaphin),GO:0005829; GO:0006887; GO:0016020; GO:0006836,cytosol; exocytosis; membrane; neurotransmitter transport,PF05835;,,,,,,,,,CPLX_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),exocytosis [GO:0006887]; neurotransmitter transport [GO:0006836] comp127150_c0_seq5,944,39.8305,0.31649652,0,0,,,,,,,,,1.00E-46,CHOYP_CPLX.1.1,,,,,,,,, comp127152_c0_seq3,392,41.8367,0.76163286,52,0,,8.00E-08,P18146,Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24),Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24),GO:0030509; GO:0001077; GO:0000979; GO:0030217; GO:0071236; GO:0071320; GO:0035690; GO:0071372; GO:0071480; GO:0071371; GO:0071363; GO:0071504; GO:0071455; GO:0071456; GO:0032869; GO:0071317; GO:0071260; GO:0071506; GO:0071383; GO:0007623; GO:0005737; GO:0003690; GO:0072110; GO:0070498; GO:0007611; GO:0060291; GO:0046872; GO:0043066; GO:0090090; GO:0000122; GO:0005654; GO:0048709; GO:0072303; GO:0043525; GO:0045944; GO:0048169; GO:0033233; GO:0001975; GO:0034465; GO:0042220; GO:0051602; GO:0045471; GO:0009749; GO:0071873; GO:0031667; GO:0003700; GO:0035914; GO:0006366; GO:0000976; GO:0060337,BMP signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation; cellular response to antibiotic; cellular response to cAMP; cellular response to drug; cellular response to follicle-stimulating hormone stimulus; cellular response to gamma radiation; cellular response to gonadotropin stimulus; cellular response to growth factor stimulus; cellular response to heparin; cellular response to hyperoxia; cellular response to hypoxia; cellular response to insulin stimulus; cellular response to isoquinoline alkaloid; cellular response to mechanical stimulus; cellular response to mycophenolic acid; cellular response to steroid hormone stimulus; circadian rhythm; cytoplasm; double-stranded DNA binding; glomerular mesangial cell proliferation; interleukin-1-mediated signaling pathway; learning or memory; long-term synaptic potentiation; metal ion binding; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; oligodendrocyte differentiation; positive regulation of glomerular metanephric mesangial cell proliferation; positive regulation of neuron apoptotic process; positive regulation of transcription from RNA polymerase II promoter; regulation of long-term neuronal synaptic plasticity; regulation of protein sumoylation; response to amphetamine; response to carbon monoxide; response to cocaine; response to electrical stimulus; response to ethanol; response to glucose stimulus; response to norepinephrine stimulus; response to nutrient levels; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription from RNA polymerase II promoter; transcription regulatory region sequence-specific DNA binding; type I interferon-mediated signaling pathway,PF11914;PF11928;,,,,,,,,,EGR1_HUMAN,Homo sapiens (Human),"BMP signaling pathway [GO:0030509]; cellular response to gamma radiation [GO:0071480]; cellular response to heparin [GO:0071504]; cellular response to mycophenolic acid [GO:0071506]; glomerular mesangial cell proliferation [GO:0072110]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of glomerular metanephric mesangial cell proliferation [GO:0072303]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of protein sumoylation [GO:0033233]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; skeletal muscle cell differentiation [GO:0035914]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366]; type I interferon signaling pathway [GO:0060337]" comp127158_c0_seq1,1120,42.6786,0.89067289,0,226,,3.00E-29,P08478,Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)],Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)],GO:0005507; GO:0016021; GO:0006518; GO:0004598; GO:0004504; GO:0030658,copper ion binding; integral to membrane; peptide metabolic process; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; transport vesicle membrane,PF03712;PF01082;PF01436;,,,,,,,,,AMDA_XENLA,Xenopus laevis (African clawed frog),peptide metabolic process [GO:0006518] comp127159_c0_seq3,346,39.3064,1.05426228,0,0,,,,,,,,,2.00E-12,CHOYP_LOC100178662.4.5,,,,,,,,, comp127164_c0_seq1,977,41.7605,0.49361938,35,43,,3.00E-64,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,6.00E-44,CHOYP_LOC100695950.6.6,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp127172_c0_seq1,632,35.6013,0.4502145,0,0,,7.00E-08,A1YEV9,Zinc finger and SCAN domain-containing protein 21,Zinc finger and SCAN domain-containing protein 21,GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;,,,,,,,,,ZSC21_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),"transcription, DNA-templated [GO:0006351]" comp127172_c0_seq2,404,37.8713,0.20783569,0,0,,4.00E-10,Q96NL3,Zinc finger protein 599,Zinc finger protein 599,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF13465;,,,,,,,,,ZN599_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127172_c0_seq3,488,35.4508,0.26212922,0,0,,9.00E-09,Q969J2,Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427),Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZKSC4_HUMAN,Homo sapiens (Human),"lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; transcription, DNA-templated [GO:0006351]" comp127172_c0_seq4,548,37.4088,0.41804822,0,0,,8.00E-10,Q96NL3,Zinc finger protein 599,Zinc finger protein 599,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF13465;,,,,,,,,,ZN599_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127173_c0_seq1,848,47.2877,0.97936563,182,593,,2.00E-23,Q16629,"Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)","Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)",GO:0003723; GO:0031124; GO:0006406; GO:0000398; GO:0048025; GO:0005654; GO:0000166; GO:0006369; GO:0008270,"RNA binding; mRNA 3'-end processing; mRNA export from nucleus; mRNA splicing, via spliceosome; negative regulation of mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding; termination of RNA polymerase II transcription; zinc ion binding",PF00076;,8.00E-55,CHOYP_LOC100371721.1.1,,,,,,,SRSF7_HUMAN,Homo sapiens (Human),"mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]" comp127174_c0_seq1,1099,43.7671,0.62929114,46030,138486,,4.00E-131,P46782,"40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]","40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]",GO:0006614; GO:0022627; GO:0003729; GO:0000184; GO:0006450; GO:0003735; GO:0006414; GO:0006413; GO:0006415; GO:0019083,"SRP-dependent cotranslational protein targeting to membrane; cytosolic small ribosomal subunit; mRNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of translational fidelity; structural constituent of ribosome; translational elongation; translational initiation; translational termination; viral transcription",PF00177;,3.00E-144,CHOYP_RS5.1.2,3.00E-173,ruditapes_lrc33063,,,,,RS5_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translational fidelity [GO:0006450]; ribosomal small subunit assembly [GO:0000028]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]" comp127177_c0_seq3,335,37.0149,0.08750078,0,0,,5.00E-16,Q4V7E0,Nef-associated protein 1 (EC 3.1.2.-) (Thioesterase NAP1),tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O),GO:0016787,hydrolase activity,PF01980;,,,,,,,,,NAP1_RAT,Rattus norvegicus (Rat),tRNA methylation [GO:0030488] comp127180_c0_seq3,459,44.2266,0.67173216,0,0,,6.00E-11,Q9NP71,Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein),Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein),GO:0009653; GO:0035538; GO:0005829; GO:0006112; GO:0055089; GO:0010255; GO:0007243; GO:0071157; GO:0090324; GO:0033137; GO:0000122; GO:0045892; GO:0005654; GO:0008284; GO:0045723; GO:0045821; GO:0045944; GO:2000505; GO:0003700; GO:0044281; GO:0005667; GO:0006351; GO:0070328,"anatomical structure morphogenesis; carbohydrate response element binding; cytosol; energy reserve metabolic process; fatty acid homeostasis; glucose mediated signaling pathway; intracellular protein kinase cascade; negative regulation of cell cycle arrest; negative regulation of oxidative phosphorylation; negative regulation of peptidyl-serine phosphorylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleoplasm; positive regulation of cell proliferation; positive regulation of fatty acid biosynthetic process; positive regulation of glycolysis; positive regulation of transcription from RNA polymerase II promoter; regulation of energy homeostasis; sequence-specific DNA binding transcription factor activity; small molecule metabolic process; transcription factor complex; transcription, DNA-dependent; triglyceride homeostasis",PF00010;,,,,,,,,,MLXPL_HUMAN,Homo sapiens (Human),"anatomical structure morphogenesis [GO:0009653]; cellular response to carbohydrate stimulus [GO:0071322]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose mediated signaling pathway [GO:0010255]; intracellular signal transduction [GO:0035556]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of energy homeostasis [GO:2000505]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]" comp127187_c0_seq1,1054,42.2201,0.64048139,414,2437,,2.00E-130,Q64270,Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha),Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha),GO:0019003; GO:0005525; GO:0030234; GO:0005850; GO:0005851; GO:0005085; GO:0032057; GO:0014003; GO:0005886; GO:0009749; GO:0009408; GO:0043434; GO:0003743,GDP binding; GTP binding; enzyme regulator activity; eukaryotic translation initiation factor 2 complex; eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor activity; negative regulation of translational initiation in response to stress; oligodendrocyte development; plasma membrane; response to glucose stimulus; response to heat; response to peptide hormone stimulus; translation initiation factor activity,PF01008;,2.00E-81,CHOYP_LOC100375693.1.2,8.00E-54,ruditapes_c14777,,,,,EI2BA_RAT,Rattus norvegicus (Rat),cellular response to stimulus [GO:0051716]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; oligodendrocyte development [GO:0014003]; positive regulation of GTPase activity [GO:0043547]; response to amino acid starvation [GO:1990928]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translation [GO:0006412]; translational initiation [GO:0006413] comp127194_c0_seq1,975,45.5385,0.57440953,2,5,,1.00E-74,Q7Z6B7,SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13),SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13),GO:0005100; GO:0007266; GO:0007411; GO:0016477; GO:0005829; GO:0051056; GO:0007264,Rho GTPase activator activity; Rho protein signal transduction; axon guidance; cell migration; cytosol; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00611;PF00620;PF00018;,9.00E-93,CHOYP_LOC100169229.1.1,,,,,,,SRGP1_HUMAN,Homo sapiens (Human),negative regulation of cell migration [GO:0030336]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp127194_c0_seq3,987,45.3901,0.57103056,0,13,,1.00E-09,Q9BE31,Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12),Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12),GO:0005096; GO:0005622; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; intracellular; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00169;PF00620;PF14604;,,,,,,,,,RHG12_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),signal transduction [GO:0007165] comp127194_c2_seq1,608,44.4079,0.67011625,12,60,,2.00E-34,P0DJJ0,SLIT-ROBO Rho GTPase-activating protein 2C (SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1),SLIT-ROBO Rho GTPase-activating protein 2C (SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1),GO:0021816; GO:0061000; GO:0051490; GO:2001224,extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration; negative regulation of dendritic spine development; negative regulation of filopodium assembly; positive regulation of neuron migration,PF00611;,5.00E-24,CHOYP_LOC100169229.1.1,,,,,,,SRG2C_HUMAN,Homo sapiens (Human),extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration [GO:0021816]; negative regulation of cell migration [GO:0030336]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of filopodium assembly [GO:0051490]; positive regulation of neuron migration [GO:2001224] comp127198_c0_seq2,446,40.1345,0.72819915,0,4,,8.00E-07,Q52KB5,Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450),Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127198_c2_seq1,1289,39.6431,0.61485277,31,4,,3.00E-35,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp127198_c2_seq3,982,39.613,0.59907322,0,0,,5.00E-17,B2RXC5,Zinc finger protein 382 (KRAB/zinc finger suppressor protein 1) (KS1) (Multiple zinc finger and krueppel-associated box protein KS1),Zinc finger protein 382 (KRAB/zinc finger suppressor protein 1) (KS1) (Multiple zinc finger and krueppel-associated box protein KS1),GO:0003677; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN382_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp127198_c2_seq4,1202,40.0998,0.62448133,0,0,,3.00E-29,A2RRD8,Zinc finger protein 320,Zinc finger protein 320,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN320_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127200_c0_seq2,1403,41.4825,0.92724318,0,0,,3.00E-161,Q6EE23,"Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)","Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)",GO:0051539; GO:0003824; GO:0051607; GO:0005789; GO:0045087; GO:0005811; GO:0008152; GO:0046872,"4 iron, 4 sulfur cluster binding; catalytic activity; defense response to virus; endoplasmic reticulum membrane; innate immune response; lipid particle; metabolic process; metal ion binding",PF04055;,,,,,,,,,RSAD2_SINCH,Siniperca chuatsi (Mandarin fish),defense response to virus [GO:0051607]; innate immune response [GO:0045087] comp127200_c0_seq5,1370,41.6788,0.92390193,0,0,,1.00E-150,Q5RH95,"Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)","Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)",GO:0051539; GO:0003824; GO:0051607; GO:0005789; GO:0045087; GO:0005811; GO:0008152; GO:0046872; GO:0009615,"4 iron, 4 sulfur cluster binding; catalytic activity; defense response to virus; endoplasmic reticulum membrane; innate immune response; lipid particle; metabolic process; metal ion binding; response to virus",PF04055;,2.00E-71,CHOYP_RSAD2.1.1,,,,,,,RSAD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; response to virus [GO:0009615] comp127203_c0_seq2,589,43.9728,0.42753746,11,12,,2.00E-65,B3DLH6,Myoferlin (Fer-1-like protein 3),Myoferlin (Fer-1-like protein 3),GO:0005901; GO:0030659; GO:0016021; GO:0031965; GO:0005543; GO:0001778,caveola; cytoplasmic vesicle membrane; integral to membrane; nuclear membrane; phospholipid binding; plasma membrane repair,PF00168;PF08165;PF08150;PF08151;PF16165;,9.00E-84,CHOYP_MYOF.2.3,,,,,,,MYOF_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778] comp127203_c1_seq1,1208,46.5232,0.53028404,0,0,,2.00E-09,A0JJX5,Synaptotagmin-4 (NTMC2T2.2) (Synaptotagmin D),Synaptotagmin-4 (NTMC2T2.2) (Synaptotagmin D),GO:0016021; GO:0008289; GO:0046872,integral to membrane; lipid binding; metal ion binding,PF00168;PF17047;,,,,,,,,,SYT4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp127203_c1_seq2,1333,46.2866,0.55484962,13,25,,1.00E-66,Q69ZN7,Myoferlin (Fer-1-like protein 3),Myoferlin (Fer-1-like protein 3),GO:0005901; GO:0034605; GO:0030659; GO:0070062; GO:0016021; GO:0031965; GO:0005543; GO:0001778; GO:0030947,caveola; cellular response to heat; cytoplasmic vesicle membrane; extracellular vesicular exosome; integral to membrane; nuclear membrane; phospholipid binding; plasma membrane repair; regulation of vascular endothelial growth factor receptor signaling pathway,PF00168;PF08165;PF08150;PF08151;PF16165;,9.00E-63,CHOYP_MYOF.3.3,4.00E-59,ruditapes_c7168,,,,,MYOF_MOUSE,Mus musculus (Mouse),cellular response to heat [GO:0034605]; plasma membrane repair [GO:0001778]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947] comp127204_c0_seq1,1478,43.3694,0.20217948,16,45,,2.00E-28,Q3TLI0,Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),GO:0005794; GO:0016192,Golgi apparatus; vesicle-mediated transport,PF12584;,,,2.00E-13,ruditapes_c15750,,,,,TPC10_MOUSE,Mus musculus (Mouse),early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891] comp127205_c0_seq1,443,44.2438,0.32941344,0,0,,6.00E-13,Q8N6Q8,Methyltransferase-like protein 25 (EC 2.1.1.-),Methyltransferase-like protein 25 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF13679;,,,,,,,,,MET25_HUMAN,Homo sapiens (Human), comp127205_c0_seq2,662,42.7492,0.30212727,5,29,,5.00E-35,Q8N6Q8,Methyltransferase-like protein 25 (EC 2.1.1.-),Methyltransferase-like protein 25 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF13679;,,,,,,,,,MET25_HUMAN,Homo sapiens (Human), comp127207_c0_seq1,611,38.7889,0.52887942,32,103,,7.00E-25,Q9BRT2,Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19),Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19),GO:0042645; GO:0005634,mitochondrial nucleoid; nucleus,,,,,,,,,,MNF1_HUMAN,Homo sapiens (Human),mitochondrial respiratory chain complex III assembly [GO:0034551]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of mitochondrial translation [GO:0070131]; regulation of insulin secretion [GO:0050796]; regulation of oxidative phosphorylation [GO:0002082]; regulation of skeletal muscle cell differentiation [GO:2001014] comp127212_c0_seq1,847,42.1488,0.48105961,61,14,,2.00E-20,O94782,Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1),Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1),GO:0006281; GO:0004197; GO:0035520; GO:0005654; GO:0006282; GO:0009411; GO:0004221; GO:0006511; GO:0004843,DNA repair; cysteine-type endopeptidase activity; monoubiquitinated protein deubiquitination; nucleoplasm; regulation of DNA repair; response to UV; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,2.00E-24,CHOYP_LOC100366443.1.1,,,,,,,UBP1_HUMAN,Homo sapiens (Human),"DNA damage response, detection of DNA damage [GO:0042769]; interstrand cross-link repair [GO:0036297]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp127213_c0_seq1,721,39.8058,0.42115578,5,10,,,,,,,,,9.00E-22,CHOYP_F188B.1.1,,,,,,,,, comp127213_c1_seq1,1830,40.6011,0.25608399,0,0,,7.00E-143,Q3UQI9,Protein FAM188B,Protein FAM188B,,,PF13898;,,,,,,,,,F188B_MOUSE,Mus musculus (Mouse), comp127213_c1_seq2,1639,41.2447,0.26135931,0,0,,9.00E-28,Q0IIH8,Protein FAM188A (Protein CARP),Protein FAM188A (Protein CARP),GO:0006915; GO:0005509; GO:0031965,apoptotic process; calcium ion binding; nuclear membrane,PF13898;,,,,,,,,,F188A_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915] comp127213_c1_seq5,686,39.7959,0.34111294,0,0,,,,,,,,,3.00E-59,CHOYP_F188B.1.1,,,,,,,,, comp127213_c1_seq7,815,41.1043,0.36018593,0,0,,8.00E-21,A0AUR5,Protein FAM188A (Protein CARP),Protein FAM188A (Protein CARP),GO:0006915; GO:0005509; GO:0005634,apoptotic process; calcium ion binding; nucleus,PF13898;,,,,,,,,,F188A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915] comp127213_c1_seq8,1510,41.3245,0.27112305,0,0,,5.00E-142,Q3UQI9,Protein FAM188B,Protein FAM188B,,,PF13898;,,,8.00E-11,ruditapes_c3409,,,,,F188B_MOUSE,Mus musculus (Mouse), comp127214_c0_seq1,1304,39.1871,0.88646731,31,63,,6.00E-82,Q68FF9,3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1),3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1),GO:0003865; GO:0006702; GO:0030154; GO:0047751; GO:0005789; GO:0016021; GO:0007548,3-oxo-5-alpha-steroid 4-dehydrogenase activity; androgen biosynthetic process; cell differentiation; cholestenone 5-alpha-reductase activity; endoplasmic reticulum membrane; integral to membrane; sex differentiation,PF02544;,1.00E-41,CHOYP_SRD5A1.1.1,,,,,,,S5A1_MOUSE,Mus musculus (Mouse),androgen biosynthetic process [GO:0006702]; cell differentiation [GO:0030154]; sex differentiation [GO:0007548] comp127217_c0_seq1,973,43.5766,0.243257,35,122,,3.00E-41,P28799,Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)],Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)],GO:0001835; GO:0008219; GO:0007566; GO:0005615; GO:0008083; GO:0043231; GO:0005739; GO:0050679; GO:0007165,blastocyst hatching; cell death; embryo implantation; extracellular space; growth factor activity; intracellular membrane-bounded organelle; mitochondrion; positive regulation of epithelial cell proliferation; signal transduction,PF00396;,,,,,,,,,GRN_HUMAN,Homo sapiens (Human),chondrocyte proliferation [GO:0035988]; male mating behavior [GO:0060179]; neural precursor cell proliferation [GO:0061351]; positive regulation of dendritic spine development [GO:0060999]; response to estradiol [GO:0032355]; signal transduction [GO:0007165]; synaptic vesicle endocytosis [GO:0048488] comp127225_c0_seq3,422,47.3934,0.73799675,0,0,,2.00E-15,Q9WTR6,Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT),Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT),GO:0015171; GO:0016021; GO:0070527; GO:0009636,amino acid transmembrane transporter activity; integral to membrane; platelet aggregation; response to toxic substance,PF13520;,,,,,,,,,XCT_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; lens fiber cell differentiation [GO:0070306]; L-glutamate transmembrane transport [GO:0089711]; platelet aggregation [GO:0070527]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636] comp127225_c0_seq4,493,46.0446,0.75076297,0,0,,,,,,,,,1.00E-23,CHOYP_LOC100378220.1.1,,,,,,,,, comp127225_c0_seq7,484,45.6612,0.68140787,0,0,,,,,,,,,2.00E-22,CHOYP_LOC100907715.1.1,,,,,,,,, comp127228_c1_seq1,1918,41.5537,0.42386103,0,0,,,,,,,,,2.00E-16,CHOYP_TM9S2.1.1,,,,,,,,, comp127228_c1_seq4,2306,41.0234,0.46542759,12,28,,2.00E-98,P58021,Transmembrane 9 superfamily member 2,Transmembrane 9 superfamily member 2,GO:0010008; GO:0016021,endosome membrane; integral to membrane,PF02990;,2.00E-16,CHOYP_PSMD1.1.1,,,,,,,TM9S2_MOUSE,Mus musculus (Mouse), comp127228_c1_seq5,1136,42.8697,0.44203888,2,26,,2.00E-61,Q4KLL4,Transmembrane 9 superfamily member 4,Transmembrane 9 superfamily member 4,GO:0016021,integral to membrane,PF02990;,,,,,,,,,TM9S4_RAT,Rattus norvegicus (Rat), comp127230_c0_seq1,1018,41.5521,0.47979867,3,0,,2.00E-41,P11837,G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis),G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis),GO:0005524; GO:0000086; GO:0051301; GO:0007059; GO:0043987; GO:0007067; GO:0005634; GO:0045840; GO:0004674,ATP binding; G2/M transition of mitotic cell cycle; cell division; chromosome segregation; histone H3-S10 phosphorylation; mitosis; nucleus; positive regulation of mitosis; protein serine/threonine kinase activity,PF00069;,1.00E-136,CHOYP_LOC100184532.1.1,,,,,,,NIMA_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-S10 phosphorylation [GO:0043987]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic nuclear division [GO:0045840]; protein phosphorylation [GO:0006468] comp127230_c0_seq2,1096,42.5182,0.44721616,10,2,,9.00E-131,Q9Z1J2,Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2),Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2),GO:0005524; GO:0051301; GO:0046872; GO:0007067; GO:0005634; GO:0004674,ATP binding; cell division; metal ion binding; mitosis; nucleus; protein serine/threonine kinase activity,PF00069;,8.00E-18,CHOYP_BRAFLDRAFT_63676.1.1,,,,,,,NEK4_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]" comp127231_c0_seq4,701,46.6476,0.60404163,45,6,,2.00E-22,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp127235_c0_seq1,1054,35.8634,0.53892264,66,132,,1.00E-19,P48375,12 kDa FK506-binding protein (FKBP) (EC 5.2.1.8) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),12 kDa FK506-binding protein (FKBP) (EC 5.2.1.8) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005528; GO:0005737; GO:0016020; GO:0003755; GO:0006457; GO:0006974,FK506 binding; cytoplasm; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding; response to DNA damage stimulus,PF00254;,,,,,,,,,FKB12_DROME,Drosophila melanogaster (Fruit fly),cellular response to DNA damage stimulus [GO:0006974]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457] comp127240_c0_seq1,1086,35.0829,0.45685105,62,19,,7.00E-07,P17105,"Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)","Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)",GO:0005524; GO:0048365; GO:0030036; GO:0004683; GO:0043197; GO:0097062; GO:0006020; GO:0008440; GO:0061003; GO:0048167,"ATP binding; Rac GTPase binding; actin cytoskeleton organization; calmodulin-dependent protein kinase activity; dendritic spine; dendritic spine maintenance; inositol metabolic process; inositol-1,4,5-trisphosphate 3-kinase activity; positive regulation of dendritic spine morphogenesis; regulation of synaptic plasticity",PF03770;,,,,,,,,,IP3KA_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; dendritic spine maintenance [GO:0097062]; inositol metabolic process [GO:0006020]; positive regulation of dendritic spine morphogenesis [GO:0061003]; regulation of synaptic plasticity [GO:0048167] comp127243_c0_seq1,2073,40.2798,0.44705057,152,96,,8.00E-25,Q6QI06,Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo),Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo),GO:0031929; GO:0031932; GO:0031532; GO:0009790; GO:0032008; GO:0030838; GO:0050731; GO:0032314; GO:0030334; GO:0051896; GO:0043022,TOR signaling cascade; TORC2 complex; actin cytoskeleton reorganization; embryo development; positive regulation of TOR signaling cascade; positive regulation of actin filament polymerization; positive regulation of peptidyl-tyrosine phosphorylation; regulation of Rac GTPase activity; regulation of cell migration; regulation of protein kinase B signaling cascade; ribosome binding,PF14663;PF14666;PF14664;PF14665;PF14668;,2.00E-15,CHOYP_LOC100367446.1.1,,,,,,,RICTR_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp127250_c0_seq1,783,42.5287,0.92095641,42,125,,1.00E-32,Q6WQJ1,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0071926; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0004806,arachidonic acid metabolic process; endocannabinoid signaling pathway; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; triglyceride lipase activity,PF01764;,,,,,,,,,DGLA_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136] comp127261_c0_seq2,1964,47.0468,0.61785799,59,0,,5.00E-130,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH6.2.3,1.00E-41,ruditapes2_c2572,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp127261_c0_seq3,1833,46.6994,0.64088079,7,10,,,,,,,,,0,CHOYP_DNAH6.3.3,,,,,,,,, comp127262_c2_seq1,898,42.8731,0.55802412,16,97,,1.00E-09,P08155,Krueppel homologous protein 1,Krueppel homolog 1 (Krueppel homologous protein 1),GO:0003677; GO:0046872; GO:0007552; GO:0045316; GO:0035075,DNA binding; metal ion binding; metamorphosis; negative regulation of compound eye photoreceptor development; response to ecdysone,,,,,,,,,,KRUH_DROME,Drosophila melanogaster (Fruit fly),"metamorphosis [GO:0007552]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of neuron projection development [GO:0010977]; regulation of transcription, DNA-templated [GO:0006355]; response to ecdysone [GO:0035075]" comp127263_c1_seq1,480,45.2083,0.53117798,17,1,,3.00E-10,Q8N5R6,Coiled-coil domain-containing protein 33 (Cancer/testis antigen 61) (CT61),Coiled-coil domain-containing protein 33 (Cancer/testis antigen 61) (CT61),,,PF00168;,1.00E-16,CHOYP_BRAFLDRAFT_118966.1.1,,,,,,,CCD33_HUMAN,Homo sapiens (Human), comp127269_c0_seq1,471,42.0382,0.3086326,23,3,,5.00E-09,Q96RT8,Gamma-tubulin complex component 5 (GCP-5),Gamma-tubulin complex component 5 (GCP-5),GO:0000086; GO:0005813; GO:0005829; GO:0008274; GO:0005874; GO:0008017; GO:0007020; GO:0000922,G2/M transition of mitotic cell cycle; centrosome; cytosol; gamma-tubulin ring complex; microtubule; microtubule binding; microtubule nucleation; spindle pole,PF04130;,,,,,,,,,GCP5_HUMAN,Homo sapiens (Human),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307] comp127272_c0_seq1,3727,49.5036,0.52317225,274,129,,3.00E-113,A2AL36,Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110),Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110),GO:0007049; GO:0051301; GO:0005737; GO:0005815,cell cycle; cell division; cytoplasm; microtubule organizing center,,1.00E-98,CHOYP_CNTRL.1.1,,,,,,,CNTRL_MOUSE,Mus musculus (Mouse),aorta development [GO:0035904]; cardiac septum development [GO:0003279]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; mitotic cell cycle [GO:0000278]; ventricular septum development [GO:0003281] comp127272_c0_seq2,587,47.8705,0.42358876,2,0,,8.00E-06,A6H759,Leucine-rich repeat-containing protein 72,Leucine-rich repeat-containing protein 72,,,,,,,,,,,,LRC72_BOVIN,Bos taurus (Bovine),melanocyte differentiation [GO:0030318] comp127275_c0_seq1,714,45.5182,0.56888041,0,9,,4.00E-45,Q15937,Zinc finger protein 79 (ZNFpT7),Zinc finger protein 79 (ZNFpT7),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZNF79_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127275_c0_seq2,1131,44.5623,0.46364976,33,78,,1.00E-118,P36508,Zinc finger protein 76 (Zinc finger protein 523),Zinc finger protein 76 (Zinc finger protein 523),GO:0003677; GO:0046872; GO:0005634; GO:0006357; GO:0006359; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase III promoter; transcription, DNA-dependent",PF00096;,1.00E-104,CHOYP_ZNF76.1.1,,,,,,,ZNF76_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase III promoter [GO:0006359]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp127278_c0_seq3,1074,44.4134,0.52319967,30,84,,6.00E-94,P55859,Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase),Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase),GO:0005737; GO:0005856; GO:0009116; GO:0004731,cytoplasm; cytoskeleton; nucleoside metabolic process; purine-nucleoside phosphorylase activity,PF01048;,8.00E-50,CHOYP_LOC100707455.1.1,,,,,,,PNPH_BOVIN,Bos taurus (Bovine),nucleoside metabolic process [GO:0009116]; purine-containing compound salvage [GO:0043101] comp127288_c0_seq1,569,43.761,0.54123879,36,37,,1.00E-14,Q641G4,Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2),Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2),GO:0030261; GO:0005634,chromosome condensation; nucleus,PF16858;PF06278;,1.00E-25,CHOYP_LOC584403.1.1,,,,,,,CNDH2_XENLA,Xenopus laevis (African clawed frog),chromosome condensation [GO:0030261] comp127292_c0_seq1,1286,41.7574,1.05830029,0,230,,4.00E-45,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,9.00E-25,CHOYP_MAN2A1.1.1,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp127296_c0_seq1,770,41.4286,0.98949393,0,18,,8.00E-12,O81077,Abscisic acid 8'-hydroxylase 2 (ABA 8'-hydroxylase 2) (EC 1.14.13.93) (Cytochrome P450 707A2),Abscisic acid 8'-hydroxylase 2 (ABA 8'-hydroxylase 2) (EC 1.14.13.93) (Cytochrome P450 707A2),GO:0010295; GO:0046345; GO:0009687; GO:0020037; GO:0016021; GO:0005506; GO:0048838; GO:0010114; GO:0006950,(+)-abscisic acid 8'-hydroxylase activity; abscisic acid catabolic process; abscisic acid metabolic process; heme binding; integral to membrane; iron ion binding; release of seed from dormancy; response to red light; response to stress,PF00067;,,,,,,,,,ABAH2_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid catabolic process [GO:0046345]; abscisic acid metabolic process [GO:0009687]; brassinosteroid biosynthetic process [GO:0016132]; brassinosteroid homeostasis [GO:0010268]; release of seed from dormancy [GO:0048838]; response to red light [GO:0010114]; response to red or far red light [GO:0009639]; sterol metabolic process [GO:0016125] comp127296_c0_seq3,1141,37.7739,1.01742799,22,167,,2.00E-49,P05183,Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase),Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase),GO:0070330; GO:0032451; GO:0017144; GO:0005789; GO:0020037; GO:0005506; GO:0070989; GO:0050649,aromatase activity; demethylase activity; drug metabolic process; endoplasmic reticulum membrane; heme binding; iron ion binding; oxidative demethylation; testosterone 6-beta-hydroxylase activity,PF00067;,,,,,,,,,CP3A2_RAT,Rattus norvegicus (Rat),drug metabolic process [GO:0017144]; oxidative demethylation [GO:0070989] comp127298_c1_seq1,278,40.2878,1.62935808,6,39,,9.00E-09,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp127301_c0_seq1,1077,44.5682,0.32391855,0,0,,,,,,,,,2.00E-26,CHOYP_BRAFLDRAFT_235936.1.1,,,,,,,,, comp127301_c0_seq2,1407,43.2125,0.31122916,17,39,,2.00E-158,Q8BJ64,"Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)","Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)",GO:0008812; GO:0050660; GO:0019285; GO:0005743,choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline; mitochondrial inner membrane,PF05199;PF00732;,4.00E-99,CHOYP_LOC100366344.1.1,,,,,,,CHDH_MOUSE,Mus musculus (Mouse),glycine betaine biosynthetic process from choline [GO:0019285] comp127301_c0_seq3,487,39.8357,0.36969853,0,0,,2.00E-07,A8FHS1,Pyrophosphatase PpaX (EC 3.6.1.1),Pyrophosphatase PpaX (EC 3.6.1.1),GO:0004427; GO:0000287,inorganic diphosphatase activity; magnesium ion binding,PF13419;,,,,,,,,,PPAX_BACP2,Bacillus pumilus (strain SAFR-032),metabolic process [GO:0008152] comp127307_c0_seq1,1323,40.2872,0.54094142,6,2,,6.00E-13,Q5XI57,Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),GO:0035085; GO:0005874; GO:0015630; GO:0031965; GO:0005886; GO:0018094; GO:0070737,"cilium axoneme; microtubule; microtubule cytoskeleton; nuclear membrane; plasma membrane; protein polyglycylation; protein-glycine ligase activity, elongating",PF03133;,,,,,,,,,TTL10_RAT,Rattus norvegicus (Rat),protein polyglycylation [GO:0018094] comp127307_c0_seq3,1536,40.4297,0.52626086,16,7,,2.00E-41,Q5XI57,Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),GO:0035085; GO:0005874; GO:0015630; GO:0031965; GO:0005886; GO:0018094; GO:0070737,"cilium axoneme; microtubule; microtubule cytoskeleton; nuclear membrane; plasma membrane; protein polyglycylation; protein-glycine ligase activity, elongating",PF03133;,4.00E-55,CHOYP_LOC578816.1.1,,,,,,,TTL10_RAT,Rattus norvegicus (Rat),protein polyglycylation [GO:0018094] comp127311_c1_seq1,522,36.3985,0.93382778,0,59,,1.00E-19,Q8LGU7,Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase NUZ) (tRNA 3 endonuclease) (tRNase Z),Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase NUZ) (tRNA 3 endonuclease) (tRNase Z),GO:0042781; GO:0046872; GO:0005634; GO:0042780,3'-tRNA processing endoribonuclease activity; metal ion binding; nucleus; tRNA 3'-end processing,PF12706;,,,,,,,,,RNZN_ARATH,Arabidopsis thaliana (Mouse-ear cress),tRNA 3'-end processing [GO:0042780]; tRNA processing [GO:0008033] comp127311_c2_seq1,405,43.7037,0.53267184,6,54,,1.00E-16,P60193,Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase ELAC) (tRNA 3 endonuclease) (tRNase Z) (Fragment),Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase ELAC) (tRNA 3 endonuclease) (tRNase Z) (Fragment),GO:0004519; GO:0046872; GO:0090305; GO:0005634; GO:0008033,endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus; tRNA processing,PF12706;,,,,,,,,,RNZN_WHEAT,Triticum aestivum (Wheat),tRNA processing [GO:0008033] comp127320_c1_seq1,976,40.9836,0.50217215,48,313,,2.00E-24,O00124,UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6),UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6),GO:0030433; GO:0030176; GO:0007338,ER-associated protein catabolic process; integral to endoplasmic reticulum membrane; single fertilization,PF00789;,,,,,,,,,UBXN8_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; single fertilization [GO:0007338] comp127323_c0_seq1,1375,39.9273,0.63541078,0,0,,4.00E-148,Q6PCB6,Alpha/beta hydrolase domain-containing protein 17C (EC 3.-.-.-),Protein ABHD17C (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 17C) (Abhydrolase domain-containing protein 17C),GO:0016787,hydrolase activity,PF12146;,,,,,,,,,F108C_HUMAN,Homo sapiens (Human), comp127323_c0_seq2,1591,39.7863,0.71403262,19,39,,6.00E-167,Q5ZJ01,Alpha/beta hydrolase domain-containing protein 17B (EC 3.-.-.-),Protein ABHD17B (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 17B) (Abhydrolase domain-containing protein 17B),GO:0005576; GO:0016787,extracellular region; hydrolase activity,PF12146;,3.00E-171,CHOYP_ISCW_ISCW010150.2.2,,,,,,,F108B_CHICK,Gallus gallus (Chicken), comp127327_c0_seq1,452,37.8319,0.3177625,1033,2081,,,,,,,,,,,2.00E-57,ruditapes_c30427,,,,,,, comp127329_c1_seq2,638,46.7085,0.89808445,2,112,,,,,,,,,3.00E-26,CHOYP_BRAFLDRAFT_120654.1.1,,,,,,,,, comp127344_c1_seq1,1203,42.1446,0.9418029,1189,2253,,4.00E-12,O07552,Stress response protein NhaX,Stress response protein NhaX,GO:0006950,response to stress,PF00582;,6.00E-14,CHOYP_NEMVEDRAFT_V1G241459.1.1,,,,,,,NHAX_BACSU,Bacillus subtilis (strain 168),response to stress [GO:0006950] comp127348_c0_seq1,784,40.1786,0.34827031,21,55,,1.00E-33,Q8CFD5,DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog),DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog),GO:0031464; GO:0016363; GO:0000109; GO:0045739; GO:0043161; GO:0051865; GO:0000209; GO:0009411; GO:0010165; GO:0006979; GO:0006283; GO:0004842,Cul4A-RING ubiquitin ligase complex; nuclear matrix; nucleotide-excision repair complex; positive regulation of DNA repair; proteasomal ubiquitin-dependent protein catabolic process; protein autoubiquitination; protein polyubiquitination; response to UV; response to X-ray; response to oxidative stress; transcription-coupled nucleotide-excision repair; ubiquitin-protein ligase activity,PF00400;,,,,,,,,,ERCC8_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283] comp127354_c0_seq2,1020,42.2549,0.46773605,45,0,,2.00E-95,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,8.00E-24,CHOYP_PKHD1L1.3.5,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp127354_c0_seq3,374,43.3155,0.63112446,1,3,,,,,,,,,6.00E-27,CHOYP_BRAFLDRAFT_108900.1.1,,,,,,,,, comp127364_c0_seq1,733,45.839,0.88499757,0,0,,3.00E-16,Q8C0M9,Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain],Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain],GO:0003948; GO:0004067; GO:0033345; GO:0008798; GO:0005737; GO:0015630; GO:0005634; GO:0006508,N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; asparaginase activity; asparagine catabolic process via L-aspartate; beta-aspartyl-peptidase activity; cytoplasm; microtubule cytoskeleton; nucleus; proteolysis,PF01112;,4.00E-20,CHOYP_ASPG.2.2,,,,,,,ASGL1_MOUSE,Mus musculus (Mouse),asparagine catabolic process via L-aspartate [GO:0033345] comp127364_c0_seq2,1119,47.0063,0.92457495,7,61,,3.00E-115,O02467,N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] (Fragment),N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] (Fragment),GO:0003948; GO:0005764; GO:0008233; GO:0006508,N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; lysosome; peptidase activity; proteolysis,PF01112;,,,,,,,,,ASPG_SPOFR,Spodoptera frugiperda (Fall armyworm), comp127368_c1_seq1,1276,41.3009,0.63439548,57,225,,7.00E-117,P42335,"Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)","Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)",GO:0005524; GO:0008440,"ATP binding; inositol-1,4,5-trisphosphate 3-kinase activity",PF03770;,5.00E-85,CHOYP_LOC590949.2.2,2.00E-37,ruditapes_c10509,,,,,IP3KB_RAT,Rattus norvegicus (Rat),cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; common myeloid progenitor cell proliferation [GO:0035726]; inositol trisphosphate metabolic process [GO:0032957]; MAPK cascade [GO:0000165]; myeloid cell homeostasis [GO:0002262]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neutrophil apoptotic process [GO:0033030]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of Ras protein signal transduction [GO:0046579]; positive thymic T cell selection [GO:0045059]; regulation of protein phosphorylation [GO:0001932] comp127370_c0_seq2,1383,40.4917,0.53041073,2,0,,5.00E-09,Q8TCU4,Alstrom syndrome protein 1,Alstrom syndrome protein 1,GO:0000086; GO:0005813; GO:0005929; GO:0005829; GO:0016197; GO:0005932; GO:0051492; GO:0000922,G2/M transition of mitotic cell cycle; centrosome; cilium; cytosol; endosomal transport; microtubule basal body; regulation of stress fiber assembly; spindle pole,PF15309;,,,,,,,,,ALMS1_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of stress fiber assembly [GO:0051492] comp127373_c0_seq1,652,45.3988,0.54989603,31,28,,1.00E-08,A0JNJ3,Spartin,Spartin,GO:0009838; GO:0051301; GO:0030496; GO:0005741; GO:0051881,abscission; cell division; midbody; mitochondrial outer membrane; regulation of mitochondrial membrane potential,PF06911;,,,,,,,,,SPG20_BOVIN,Bos taurus (Bovine),abscission [GO:0009838]; adipose tissue development [GO:0060612]; cell division [GO:0051301]; lipid particle organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881] comp127373_c0_seq2,1042,45.2015,0.4141582,6,13,,2.00E-29,C5CBU4,AAA ATPase forming ring-shaped complexes (ARC),AAA ATPase forming ring-shaped complexes (ARC),GO:0005524; GO:0016887; GO:0019941; GO:0010498; GO:0000502,ATP binding; ATPase activity; modification-dependent protein catabolic process; proteasomal protein catabolic process; proteasome complex,PF00004;PF16450;,1.00E-103,CHOYP_SPAST.1.1,,,,,,,ARC_MICLC,Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus),modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498] comp127373_c0_seq3,1091,45.6462,0.40603361,1,5,,8.00E-132,Q6AZT2,Spastin (EC 3.6.4.3),Spastin (EC 3.6.4.3),GO:0005524; GO:0043014; GO:0007409; GO:0048487; GO:0007049; GO:0051301; GO:0005813; GO:0016021; GO:0005874; GO:0008017; GO:0001578; GO:0051013; GO:0008568; GO:0005634; GO:0048471; GO:0031117; GO:0034214; GO:0051260,ATP binding; alpha-tubulin binding; axonogenesis; beta-tubulin binding; cell cycle; cell division; centrosome; integral to membrane; microtubule; microtubule binding; microtubule bundle formation; microtubule severing; microtubule-severing ATPase activity; nucleus; perinuclear region of cytoplasm; positive regulation of microtubule depolymerization; protein hexamerization; protein homooligomerization,PF00004;,1.00E-33,CHOYP_LOC578480.1.1,,,,,,,SPAST_XENLA,Xenopus laevis (African clawed frog),anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; ER to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear envelope reassembly [GO:0031468]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260] comp127374_c0_seq1,1002,42.016,0.94540073,3,194,,1.00E-43,Q8K157,Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase),Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase),GO:0004034; GO:0030246; GO:0005737; GO:0019318,aldose 1-epimerase activity; carbohydrate binding; cytoplasm; hexose metabolic process,PF01263;,,,6.00E-30,ruditapes_c14942,,,,,GALM_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006] comp127377_c0_seq1,334,32.3353,0.94533475,89,0,,,,,,,,,,,2.00E-16,ruditapes_c29520,,,,,,, comp127380_c0_seq1,1499,44.1628,0.68847794,48,63,,1.00E-160,Q9UQ03,Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96),Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96),GO:0015629; GO:0030036; GO:0051015; GO:0005737; GO:0016020,actin cytoskeleton; actin cytoskeleton organization; actin filament binding; cytoplasm; membrane,PF08953;PF00400;,3.00E-63,CHOYP_LOC100122439.1.1,,,,,,,COR2B_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036] comp127380_c0_seq2,409,43.2763,0.52363021,7,0,,,,,,,,,2.00E-13,CHOYP_CORO.1.1,,,,,,,,, comp127382_c1_seq1,929,38.5361,0.6474691,39,43,,2.00E-12,Q8CFF0,Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11),Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11),GO:0003950,NAD+ ADP-ribosyltransferase activity,PF00644;PF02825;,,,,,,,,,PAR11_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] comp127386_c0_seq1,1011,39.367,0.54913363,157,431,,8.00E-80,Q66I61,UPF0428 protein CXorf56 homolog,UPF0428 protein CXorf56 homolog,,,,2.00E-114,CHOYP_PHUM_PHUM454190.1.1,,,,,,,CX056_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp127390_c0_seq2,1276,42.4765,0.57873305,92,290,,2.00E-81,O08760,N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)],N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)],GO:0034039; GO:0006284; GO:0003684; GO:0008017; GO:0005739; GO:0016363; GO:0016607; GO:0006289; GO:0033158; GO:0006355; GO:0006979; GO:0009314,"8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; base-excision repair; damaged DNA binding; microtubule binding; mitochondrion; nuclear matrix; nuclear speck; nucleotide-excision repair; regulation of protein import into nucleus, translocation; regulation of transcription, DNA-dependent; response to oxidative stress; response to radiation",PF00730;PF07934;,2.00E-38,CHOYP_LOC100378570.1.1,,,,,,,OGG1_MOUSE,Mus musculus (Mouse),"acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of protein import into nucleus, translocation [GO:0033158]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]" comp127392_c0_seq2,1211,37.6548,0.9563701,29,460,,2.00E-10,Q4R5J4,Transgelin-3,Transgelin-3,GO:0007517,muscle organ development,PF00402;PF00307;,7.00E-45,CHOYP_TAGL3.1.1,1.00E-52,ruditapes_lrc33479,,,,,TAGL3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp127392_c0_seq3,1157,37.6837,1.02359331,0,0,,,,,,,,,,,3.00E-65,ruditapes2_c170,,,,,,, comp127392_c0_seq4,1518,36.0343,0.97499441,333,2004,,5.00E-08,Q24799,Myophilin,Myophilin,,,PF00402;PF00307;,,,,,,,,,MYPH_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp127396_c0_seq1,1069,43.3115,0.47917642,15,218,,2.00E-09,Q6NV72,WD repeat-containing protein C2orf44 homolog,WD repeat and coiled-coil-containing protein,,,PF15390;,,,,,,,,,CB044_MOUSE,Mus musculus (Mouse),protein oligomerization [GO:0051259] comp127403_c1_seq3,435,49.8851,0.72476324,0,0,,1.00E-06,A8T6P4,Rab effector MyRIP (Exophilin-8) (Myosin VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c),Rab effector MyRIP (Exophilin-8) (Myosin VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c),GO:0006886; GO:0046872; GO:0048471; GO:0030133,intracellular protein transport; metal ion binding; perinuclear region of cytoplasm; transport vesicle,PF02318;PF04698;,1.00E-17,CHOYP_UNC89.1.19,,,,,,,MYRIP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),intracellular protein transport [GO:0006886] comp127406_c0_seq1,1189,42.9773,1.02149126,0,84,,2.00E-75,P15589,Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),GO:0005789; GO:0007565; GO:0016021; GO:0007611; GO:0046872; GO:0005635; GO:0008284; GO:0043627; GO:0009268; GO:0043434; GO:0043588; GO:0008202; GO:0004773,endoplasmic reticulum membrane; female pregnancy; integral to membrane; learning or memory; metal ion binding; nuclear envelope; positive regulation of cell proliferation; response to estrogen stimulus; response to pH; response to peptide hormone stimulus; skin development; steroid metabolic process; steryl-sulfatase activity,PF00884;,,,,,,,,,STS_RAT,Rattus norvegicus (Rat),female pregnancy [GO:0007565]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; response to estrogen [GO:0043627]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid metabolic process [GO:0008202] comp127406_c0_seq2,928,45.3664,0.90377933,0,0,,2.00E-76,P08842,Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),GO:0005794; GO:0005788; GO:0005789; GO:0005768; GO:0008544; GO:0007565; GO:0006687; GO:0016021; GO:0005764; GO:0046872; GO:0005886; GO:0043687; GO:0044281; GO:0006706; GO:0004773,Golgi apparatus; endoplasmic reticulum lumen; endoplasmic reticulum membrane; endosome; epidermis development; female pregnancy; glycosphingolipid metabolic process; integral to membrane; lysosome; metal ion binding; plasma membrane; post-translational protein modification; small molecule metabolic process; steroid catabolic process; steryl-sulfatase activity,PF00884;,,,,,,,,,STS_HUMAN,Homo sapiens (Human),epidermis development [GO:0008544]; female pregnancy [GO:0007565]; glycosphingolipid metabolic process [GO:0006687]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; response to estrogen [GO:0043627]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid catabolic process [GO:0006706] comp127406_c0_seq3,596,47.9866,0.82231636,0,0,,9.00E-29,Q32KH5,N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase),N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase),GO:0043890; GO:0005764; GO:0046872,N-acetylgalactosamine-6-sulfatase activity; lysosome; metal ion binding,PF00884;,,,,,,,,,GALNS_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),metabolic process [GO:0008152] comp127408_c0_seq1,909,40.7041,0.51383461,26,115,,5.00E-28,Q99NH3,Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1),Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1),GO:0017112; GO:0019900; GO:0015031,Rab guanyl-nucleotide exchange factor activity; kinase binding; protein transport,PF06428;,2.00E-36,CHOYP_BRAFLDRAFT_199346.3.3,,,,,,,R3GEF_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp127411_c0_seq1,837,38.4707,0.22756754,2,0,,,,,,,,,2.00E-18,CHOYP_LOC590843.1.1,,,,,,,,, comp127414_c0_seq1,495,37.7778,0.62497391,42,258,,2.00E-44,Q4R6C2,Zinc finger protein 383,Zinc finger protein 383,GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13465;,,,8.00E-12,ruditapes_c21757,,,,,ZN383_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127415_c0_seq1,1414,42.645,0.5678173,17,9,,5.00E-61,Q5HYC2,Uncharacterized protein KIAA2026,Uncharacterized protein KIAA2026,,,,,,,,,,,,K2026_HUMAN,Homo sapiens (Human), comp127415_c0_seq2,1298,42.1418,0.57936242,0,0,,1.00E-12,P13709,Homeotic protein female sterile (Fragile-chorion membrane protein),Homeotic protein female sterile (Fragile-chorion membrane protein),GO:0007476; GO:0016021; GO:0045892; GO:0007362,"imaginal disc-derived wing morphogenesis; integral to membrane; negative regulation of transcription, DNA-dependent; terminal region determination",PF17035;PF17105;PF00439;,,,,,,,,,FSH_DROME,Drosophila melanogaster (Fruit fly),"dendrite morphogenesis [GO:0048813]; imaginal disc-derived wing morphogenesis [GO:0007476]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; terminal region determination [GO:0007362]" comp127416_c0_seq2,688,40.843,0.27940043,19,40,,3.00E-28,Q5RKI9,"Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial)","Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial)",GO:0005739; GO:0032790; GO:0006412,mitochondrion; ribosome disassembly; translation,PF01765;,,,,,,,,,RRFM_RAT,Rattus norvegicus (Rat),mitochondrial translational termination [GO:0070126]; ribosome disassembly [GO:0032790] comp127418_c0_seq1,412,38.3495,0.66441833,6,23,,5.00E-12,Q5UPK7,Putative GMC-type oxidoreductase L128 (EC 1.-.-.-),Putative GMC-type oxidoreductase L128 (EC 1.-.-.-),GO:0006066; GO:0008812; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding,PF05199;PF00732;,,,,,,,,,YL128_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp127418_c1_seq1,715,37.0629,1.12815347,23,96,,3.00E-39,Q9WWW2,Alcohol dehydrogenase [acceptor] (EC 1.1.99.-),Alcohol dehydrogenase [acceptor] (EC 1.1.99.-),GO:0006066; GO:0008812; GO:0050660; GO:0005886,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding; plasma membrane,PF05199;PF00732;,5.00E-25,CHOYP_LOC100646609.1.1,,,,,,,ALKJ_PSEPU,Pseudomonas putida (Arthrobacter siderocapsulatus), comp127418_c2_seq2,490,44.2857,1.03586929,4,21,,8.00E-43,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,,,,,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp127420_c0_seq1,1312,42.7591,0.48654513,88,158,,8.00E-144,Q3SWY2,Integrin-linked protein kinase (EC 2.7.11.1),Integrin-linked protein kinase (EC 2.7.11.1),GO:0005524; GO:0005925; GO:0030027; GO:0005886; GO:0004674; GO:0009966; GO:0030017,ATP binding; focal adhesion; lamellipodium; plasma membrane; protein serine/threonine kinase activity; regulation of signal transduction; sarcomere,PF12796;PF07714;,5.00E-167,CHOYP_ISCW_ISCW017519.2.2,,,,,,,ILK_BOVIN,Bos taurus (Bovine), comp127423_c0_seq1,1743,38.4968,1.13414259,26,388,,2.00E-33,Q55EX9,Putative methyltransferase DDB_G0268948 (EC 2.1.1.-),Putative methyltransferase DDB_G0268948 (EC 2.1.1.-),GO:0008168; GO:0045335,methyltransferase activity; phagocytic vesicle,PF08241;,,,,,,,,,Y8948_DICDI,Dictyostelium discoideum (Slime mold),methylation [GO:0032259] comp127427_c0_seq1,372,44.086,0.11154387,9,38,,4.00E-27,Q9D1E8,1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon),1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon),GO:0003841; GO:0016024; GO:0006639; GO:0005789; GO:0016021; GO:0005739; GO:0005635,1-acylglycerol-3-phosphate O-acyltransferase activity; CDP-diacylglycerol biosynthetic process; acylglycerol metabolic process; endoplasmic reticulum membrane; integral to membrane; mitochondrion; nuclear envelope,PF16076;PF01553;,,,,,,,,,PLCE_MOUSE,Mus musculus (Mouse),acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244] comp127433_c0_seq1,742,42.3181,0.33821704,18,65,,3.00E-101,Q90XD2,"Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH)","Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH)",GO:0008783; GO:0046872; GO:0005739; GO:0033388; GO:0008295,agmatinase activity; metal ion binding; mitochondrion; putrescine biosynthetic process from arginine; spermidine biosynthetic process,PF00491;,3.00E-72,CHOYP_LOC100180543.1.1,2.00E-14,ruditapes_c30010,,,,,SPEB_CHICK,Gallus gallus (Chicken),putrescine biosynthetic process from arginine [GO:0033388]; spermidine biosynthetic process [GO:0008295] comp127434_c0_seq1,1371,41.9402,0.44817097,0,0,,3.00E-09,Q54C85,Importin-13 homolog A,Importin-13 homolog A,GO:0005737; GO:0006886; GO:0005635,cytoplasm; intracellular protein transport; nuclear envelope,,2.00E-51,CHOYP_IPO13.1.1,,,,,,,IP13A_DICDI,Dictyostelium discoideum (Slime mold),protein import into nucleus [GO:0006606] comp127434_c0_seq2,1866,42.283,0.44402676,22,81,,7.00E-146,Q5ZIC8,Importin-13 (Imp13),Importin-13 (Imp13),GO:0005737; GO:0005634; GO:0015031,cytoplasm; nucleus; protein transport,PF08389;,3.00E-51,CHOYP_IPO13.1.1,,,,,,,IPO13_CHICK,Gallus gallus (Chicken),protein import into nucleus [GO:0006606] comp127448_c1_seq1,2416,42.4255,0.58612218,29,18,,0,Q5ZLT0,Exportin-7,Exportin-7,GO:0005737; GO:0006886; GO:0005634,cytoplasm; intracellular protein transport; nucleus,PF03810;,0,CHOYP_XPO7.1.1,,,,,,,XPO7_CHICK,Gallus gallus (Chicken),protein export from nucleus [GO:0006611] comp127464_c0_seq1,461,37.3102,0.83417059,23,29,,2.00E-52,Q0P5D3,G1/S-specific cyclin-D2,G1/S-specific cyclin-D2,GO:0007049; GO:0051301; GO:0000785; GO:0000307; GO:0005829; GO:0031965; GO:0005730; GO:0045737,cell cycle; cell division; chromatin; cyclin-dependent protein kinase holoenzyme complex; cytosol; nuclear membrane; nucleolus; positive regulation of cyclin-dependent protein kinase activity,PF02984;PF00134;,2.00E-58,CHOYP_CCND.1.1,,,,,,,CCND2_BOVIN,Bos taurus (Bovine),cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737] comp127464_c2_seq1,606,36.4686,0.89484273,39,24,,,,,,,,,,,2.00E-64,ruditapes_c29368,,,,,,, comp127468_c0_seq1,251,40.239,0.10909264,5,16,,2.00E-08,O73694,Early growth response protein 1 (EGR-1) (Zinc finger protein ZENK) (Fragment),Early growth response protein 1 (EGR-1) (Zinc finger protein ZENK) (Fragment),GO:0046872; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,EGR1_SERCA,Serinus canaria (Island canary) (Fringilla canaria),"positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp127468_c2_seq1,1217,36.8118,0.48646091,5,8,,2.00E-10,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp127468_c2_seq2,1110,37.2973,0.51857772,0,3,,2.00E-09,Q66JF8,Protein odd-skipped-related 1 (XOsr1),Protein odd-skipped-related 1 (XOsr1),GO:0046872; GO:0000122; GO:0003676; GO:0005634; GO:0048793; GO:0006351,"metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleic acid binding; nucleus; pronephros development; transcription, DNA-dependent",PF13912;,,,,,,,,,OSR1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"angioblast cell differentiation [GO:0035779]; intermediate mesoderm development [GO:0048389]; mesendoderm development [GO:0048382]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pectoral fin development [GO:0033339]; pronephric distal tubule development [GO:0035777]; pronephric glomerulus morphogenesis [GO:0035775]; pronephric nephron tubule epithelial cell differentiation [GO:0035778]; pronephric proximal tubule development [GO:0035776]; pronephros development [GO:0048793]; regulation of endodermal cell differentiation [GO:1903224]; regulation of nodal signaling pathway [GO:1900107]; transcription, DNA-templated [GO:0006351]" comp127468_c2_seq3,803,36.3636,0.56601205,6,0,,5.00E-11,Q8N184,Zinc finger protein 567,Zinc finger protein 567,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN567_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp127470_c1_seq1,1385,47.2202,0.79103709,4,11,,3.00E-163,Q9MZL5,Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2),Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2),GO:0070509; GO:0008331; GO:0051928; GO:0042383; GO:0007268; GO:0007601; GO:0005891,calcium ion import; high voltage-gated calcium channel activity; positive regulation of calcium ion transport; sarcolemma; synaptic transmission; visual perception; voltage-gated calcium channel complex,PF00625;PF12052;,8.00E-108,CHOYP_CACNB2.1.1,,,,,,,CACB2_BOVIN,Bos taurus (Bovine),calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; neuromuscular junction development [GO:0007528]; positive regulation of calcium ion transport [GO:0051928]; regulation of voltage-gated calcium channel activity [GO:1901385]; visual perception [GO:0007601] comp127470_c1_seq5,1334,46.3268,0.769203,0,0,,4.00E-163,Q08289,Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB),Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB),GO:0007411; GO:0070509; GO:0005887; GO:0007528; GO:0051928; GO:0042383; GO:0007268; GO:0007601; GO:0005245; GO:0005891,axon guidance; calcium ion import; integral to plasma membrane; neuromuscular junction development; positive regulation of calcium ion transport; sarcolemma; synaptic transmission; visual perception; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF00625;PF12052;,8.00E-108,CHOYP_CACNB2.1.1,,,,,,,CACB2_HUMAN,Homo sapiens (Human),calcium ion import [GO:0070509]; cardiac conduction [GO:0061337]; chemical synaptic transmission [GO:0007268]; establishment of protein localization to plasma membrane [GO:0090002]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; neuromuscular junction development [GO:0007528]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of voltage-gated calcium channel activity [GO:1901385]; visual perception [GO:0007601] comp127470_c1_seq6,410,42.9268,0.53080517,1,0,,,,,,,,,4.00E-16,CHOYP_CACB1.1.1,,,,,,,,, comp127473_c0_seq1,791,38.3059,0.35433127,16,197,,1.00E-30,O75935,Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22),Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22),GO:0000086; GO:0019886; GO:0005813; GO:0032154; GO:0000777; GO:0000910; GO:0005829; GO:0005869; GO:0007017; GO:0030496; GO:0007067; GO:0048471; GO:0005819; GO:0005198,G2/M transition of mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class II; centrosome; cleavage furrow; condensed chromosome kinetochore; cytokinesis; cytosol; dynactin complex; microtubule-based process; midbody; mitosis; perinuclear region of cytoplasm; spindle; structural molecule activity,PF07426;,,,,,,,,,DCTN3_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; ER to Golgi vesicle-mediated transport [GO:0006888]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067] comp127473_c0_seq2,773,37.9043,0.36934591,25,286,,1.00E-32,Q0P5A1,Dynactin subunit 3,Dynactin subunit 3,GO:0005813; GO:0032154; GO:0000777; GO:0000910; GO:0005869; GO:0007017; GO:0030496; GO:0007067; GO:0048471; GO:0005819,centrosome; cleavage furrow; condensed chromosome kinetochore; cytokinesis; dynactin complex; microtubule-based process; midbody; mitosis; perinuclear region of cytoplasm; spindle,PF07426;,,,,,,,,,DCTN3_BOVIN,Bos taurus (Bovine),cytokinesis [GO:0000910]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067] comp127479_c0_seq2,2248,34.8754,0.94337885,0,154,,2.00E-20,P97353,"Galactoside 2-alpha-L-fucosyltransferase 3 (EC 2.4.1.69) (Alpha(1,2)FT 3) (Fucosyltransferase 10) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 3) (Secretory blood group protein 1)","Galactoside 2-alpha-L-fucosyltransferase 3 (EC 2.4.1.69) (Alpha(1,2)FT 3) (Fucosyltransferase 10) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 3) (Secretory blood group protein 1)",GO:0032580; GO:0008107; GO:0016021; GO:0006486,Golgi cisterna membrane; galactoside 2-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation,PF01531;,,,,,,,,,SEC1_MOUSE,Mus musculus (Mouse),protein glycosylation [GO:0006486] comp127492_c1_seq2,729,37.1742,0.48720893,9,0,,3.00E-34,A2VE56,PHD finger protein 20-like protein 1,PHD finger protein 20-like protein 1,,,PF12618;,,,,,,,,,P20L1_BOVIN,Bos taurus (Bovine), comp127492_c2_seq2,1227,41.3203,0.32962821,3,0,,4.00E-32,Q8CCJ9,PHD finger protein 20-like protein 1,PHD finger protein 20-like protein 1,GO:0008270,zinc ion binding,PF12618;,9.00E-31,CHOYP_P20L1.1.1,,,,,,,P20L1_MOUSE,Mus musculus (Mouse), comp127494_c1_seq1,3069,42.1636,0.52962807,260,293,,0,P98199,Probable phospholipid-transporting ATPase ID (EC 3.6.3.1) (ATPase class I type 8B member 2),Phospholipid-transporting ATPase ID (EC 3.6.3.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2),GO:0005524; GO:0019829; GO:0016021; GO:0000287; GO:0004012,ATP binding; cation-transporting ATPase activity; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity,PF00122;PF16212;PF16209;,0,CHOYP_ATP8B2.1.3,1.00E-32,ruditapes_c7749,,,,,AT8B2_MOUSE,Mus musculus (Mouse),Golgi organization [GO:0007030] comp127501_c0_seq2,585,41.3675,0.88108513,62,47,,2.00E-20,P51910,Apolipoprotein D (Apo-D) (ApoD),Apolipoprotein D (Apo-D) (ApoD),GO:0007568; GO:0007420; GO:0015485; GO:0022626; GO:0030425; GO:0005783; GO:0005615; GO:0006006; GO:0006629; GO:2000405; GO:1900016; GO:0051895; GO:0060588; GO:0071638; GO:0010642; GO:0042308; GO:0048662; GO:2000098; GO:0043025; GO:0048471; GO:0014012; GO:0042493; GO:0000302; GO:0042246; GO:0005215,aging; brain development; cholesterol binding; cytosolic ribosome; dendrite; endoplasmic reticulum; extracellular space; glucose metabolic process; lipid metabolic process; negative regulation of T cell migration; negative regulation of cytokine production involved in inflammatory response; negative regulation of focal adhesion assembly; negative regulation of lipoprotein lipid oxidation; negative regulation of monocyte chemotactic protein-1 production; negative regulation of platelet-derived growth factor receptor signaling pathway; negative regulation of protein import into nucleus; negative regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell-matrix adhesion; neuronal cell body; perinuclear region of cytoplasm; peripheral nervous system axon regeneration; response to drug; response to reactive oxygen species; tissue regeneration; transporter activity,PF08212;,,,,,,,,,APOD_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246] comp127508_c1_seq1,1330,48.4962,0.42419672,41,0,,7.00E-79,Q8NEG5,E3 ubiquitin-protein ligase ZSWIM2 (EC 6.3.2.-) (MEKK1-related protein X) (MEX) (ZZ-type zinc finger-containing protein 2) (Zinc finger SWIM domain-containing protein 2),E3 ubiquitin-protein ligase ZSWIM2 (EC 6.3.2.-) (MEKK1-related protein X) (MEX) (ZZ-type zinc finger-containing protein 2) (Zinc finger SWIM domain-containing protein 2),GO:0006915; GO:0000209; GO:0042981; GO:0004842; GO:0008270,apoptotic process; protein polyubiquitination; regulation of apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF04434;PF13639;PF00569;,,,,,,,,,ZSWM2_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; protein polyubiquitination [GO:0000209] comp127508_c1_seq2,857,47.7246,0.50080325,0,0,,3.00E-08,Q9M2S6,E3 ubiquitin-protein ligase SDIR1 (EC 6.3.2.-) (Protein salt- and drought-induced RING finger1),E3 ubiquitin-protein ligase SDIR1 (EC 6.3.2.-) (Protein salt- and drought-induced RING finger1),GO:0005783; GO:0016021; GO:0043231; GO:0031090; GO:0009789; GO:0009737; GO:0009651; GO:0009414; GO:0004842; GO:0008270,endoplasmic reticulum; integral to membrane; intracellular membrane-bounded organelle; organelle membrane; positive regulation of abscisic acid mediated signaling pathway; response to abscisic acid stimulus; response to salt stress; response to water deprivation; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,2.00E-114,CHOYP_LOC100371610.2.2,,,,,,,SDIR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to abscisic acid [GO:0009737]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414] comp127512_c0_seq1,973,39.7739,1.12489375,277,2080,,9.00E-06,Q8K482,EMILIN-2 (Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2),EMILIN-2 (Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2),GO:0007155; GO:0005581,cell adhesion; collagen,PF00386;PF07546;,,,,,,,,,EMIL2_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp127520_c0_seq1,740,34.5946,0.81453584,8954,36175,,5.00E-37,Q66KU2,Protein transport protein Sec61 subunit gamma,Protein transport protein Sec61 subunit gamma,GO:0015450; GO:0005789; GO:0016021; GO:0045047; GO:0008565,P-P-bond-hydrolysis-driven protein transmembrane transporter activity; endoplasmic reticulum membrane; integral to membrane; protein targeting to ER; protein transporter activity,PF00584;,4.00E-51,CHOYP_SEC61G.3.3,1.00E-61,ruditapes2_c4591,,,,,SC61G_XENLA,Xenopus laevis (African clawed frog),protein targeting to ER [GO:0045047] comp127527_c1_seq1,1013,40.3751,0.46370508,61,257,,6.00E-117,Q29RK9,MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B),MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B),GO:0046872,metal ion binding,PF03637;,2.00E-145,CHOYP_MOB3B.1.2,,,,,,,MOB3B_BOVIN,Bos taurus (Bovine), comp127528_c1_seq2,1266,45.9716,0.69956352,116,23,,3.00E-15,Q5U303,TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TGF-beta-activated kinase 1-binding protein 2),TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TGF-beta-activated kinase 1-binding protein 2),GO:0070530; GO:0005829; GO:0007507; GO:0005634; GO:0043123; GO:0045860; GO:0008270,K63-linked polyubiquitin binding; cytosol; heart development; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein kinase activity; zinc ion binding,PF02845;,2.00E-20,CHOYP_TAB3.1.1,3.00E-22,ruditapes_c21222,,,,,TAB2_RAT,Rattus norvegicus (Rat),heart development [GO:0007507]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein kinase activity [GO:0045860] comp127536_c2_seq1,2190,42.6484,0.35638773,36,15,,5.00E-82,Q864S8,Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog),Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog),GO:0033593; GO:0005813; GO:0051298; GO:0000910; GO:0006302; GO:0000724; GO:0043015; GO:0033600; GO:0006289; GO:0005634; GO:0045893; GO:0030141; GO:0003697,"BRCA2-MAGE-D1 complex; centrosome; centrosome duplication; cytokinesis; double-strand break repair; double-strand break repair via homologous recombination; gamma-tubulin binding; negative regulation of mammary gland epithelial cell proliferation; nucleotide-excision repair; nucleus; positive regulation of transcription, DNA-dependent; secretory granule; single-stranded DNA binding",PF09169;PF09103;PF09104;PF00634;PF09121;,,,,,,,,,BRCA2_FELCA,Felis catus (Cat) (Felis silvestris catus),"centrosome duplication [GO:0051298]; chromosome organization [GO:0051276]; cytokinesis [GO:0000910]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell proliferation [GO:0042127]; regulation of transcription, DNA-templated [GO:0006355]" comp127536_c3_seq1,1205,41.9917,0.4145486,67,65,,3.00E-51,P51587,Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein),Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein),GO:0033593; GO:0006978; GO:0010484; GO:0010485; GO:0007420; GO:0007569; GO:0005813; GO:0051298; GO:0000910; GO:0000724; GO:0008585; GO:0030097; GO:0001833; GO:0042771; GO:0007141; GO:0033600; GO:0005654; GO:0006289; GO:0001556; GO:0045931; GO:0045893; GO:0032465; GO:0048478; GO:0010225; GO:0010165; GO:0010332; GO:0030141; GO:0003697; GO:0007283,"BRCA2-MAGE-D1 complex; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; brain development; cell aging; centrosome; centrosome duplication; cytokinesis; double-strand break repair via homologous recombination; female gonad development; hemopoiesis; inner cell mass cell proliferation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; male meiosis I; negative regulation of mammary gland epithelial cell proliferation; nucleoplasm; nucleotide-excision repair; oocyte maturation; positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-dependent; regulation of cytokinesis; replication fork protection; response to UV-C; response to X-ray; response to gamma radiation; secretory granule; single-stranded DNA binding; spermatogenesis",PF09169;PF09103;PF09104;PF00634;PF09121;,8.00E-19,CHOYP_BRCA2.1.2,,,,,,,BRCA2_HUMAN,Homo sapiens (Human),"brain development [GO:0007420]; cell aging [GO:0007569]; centrosome duplication [GO:0051298]; chromosome breakage [GO:0031052]; cytokinesis [GO:0000910]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; homologous recombination-dependent replication fork processing [GO:1990426]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cytokinesis [GO:0032465]; replication fork protection [GO:0048478]; response to estradiol [GO:0032355]; response to gamma radiation [GO:0010332]; response to nutrient [GO:0007584]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; strand displacement [GO:0000732]; telomere maintenance via recombination [GO:0000722]" comp127540_c0_seq1,1487,36.8527,0.44505492,35,119,,5.00E-53,Q9WVM3,Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen),Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen),GO:0005680; GO:0051301; GO:0007067; GO:0070979,anaphase-promoting complex; cell division; mitosis; protein K11-linked ubiquitination,PF13181;,1.00E-36,CHOYP_APC7.1.1,,,,,,,APC7_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979] comp127542_c0_seq2,1179,43.0874,0.45955915,55,63,,2.00E-162,P91891,Protein Mo25 (dMo25),Protein Mo25 (dMo25),GO:0001700,embryonic development via the syncytial blastoderm,PF08569;,4.00E-162,CHOYP_MO25.1.1,,,,,,,MO25_DROME,Drosophila melanogaster (Fruit fly),embryonic development via the syncytial blastoderm [GO:0001700]; sensory perception of pain [GO:0019233] comp127544_c0_seq2,1327,39.6383,0.55379514,6,0,,2.00E-15,P80108,Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),GO:0006507; GO:0002042; GO:0071277; GO:0071397; GO:0035690; GO:0071467; GO:0071401; GO:0002062; GO:0002430; GO:0005615; GO:0004621; GO:0097241; GO:0008286; GO:0005765; GO:0008285; GO:0010897; GO:0001503; GO:0046470; GO:0010694; GO:0043065; GO:0045919; GO:0010595; GO:0010907; GO:0010983; GO:0035774; GO:0051044; GO:0010867; GO:0005578; GO:1900076; GO:0009749; GO:0017080; GO:0070633,GPI anchor release; cell migration involved in sprouting angiogenesis; cellular response to calcium ion; cellular response to cholesterol; cellular response to drug; cellular response to pH; cellular response to triglyceride; chondrocyte differentiation; complement receptor mediated signaling pathway; extracellular space; glycosylphosphatidylinositol phospholipase D activity; hematopoietic stem cell migration to bone marrow; insulin receptor signaling pathway; lysosomal membrane; negative regulation of cell proliferation; negative regulation of triglyceride catabolic process; ossification; phosphatidylcholine metabolic process; positive regulation of alkaline phosphatase activity; positive regulation of apoptotic process; positive regulation of cytolysis; positive regulation of endothelial cell migration; positive regulation of glucose metabolic process; positive regulation of high-density lipoprotein particle clearance; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of membrane protein ectodomain proteolysis; positive regulation of triglyceride biosynthetic process; proteinaceous extracellular matrix; regulation of cellular response to insulin stimulus; response to glucose stimulus; sodium channel regulator activity; transepithelial transport,PF01839;PF00882;,,,,,,,,,PHLD_HUMAN,Homo sapiens (Human),cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633] comp127558_c0_seq1,356,46.3483,0.68756098,1,6,,,,,,,,,5.00E-78,CHOYP_MYO9.3.5,,,,,,,,, comp127558_c0_seq2,443,44.4695,0.83146491,2,16,,2.00E-61,Q01989,Myosin heavy chain 95F (95F MHC) (Protein jaguar),Myosin heavy chain 95F (95F MHC) (Protein jaguar),GO:0005524; GO:0042623; GO:0051015; GO:0007015; GO:0030048; GO:0055059; GO:0045167; GO:0045178; GO:0045175; GO:0007298; GO:0005938; GO:0045217; GO:0019749; GO:0007391; GO:0030139; GO:0040001; GO:0045172; GO:0007560; GO:0070865; GO:0008363; GO:0061024; GO:0000146; GO:0005875; GO:0008017; GO:0047497; GO:0016333; GO:0031476; GO:0051647; GO:0006997; GO:0045921; GO:0030589; GO:0032956; GO:0032880; GO:0007291; GO:0030317; GO:0007051,"ATP binding; ATPase activity, coupled; actin filament binding; actin filament organization; actin filament-based movement; asymmetric neuroblast division; asymmetric protein localization involved in cell fate determination; basal part of cell; basal protein localization; border follicle cell migration; cell cortex; cell-cell junction maintenance; cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte; dorsal closure; endocytic vesicle; establishment of mitotic spindle localization; germline ring canal; imaginal disc morphogenesis; investment cone; larval chitin-based cuticle development; membrane organization; microfilament motor activity; microtubule associated complex; microtubule binding; mitochondrion transport along microtubule; morphogenesis of follicular epithelium; myosin VI complex; nucleus localization; nucleus organization; positive regulation of exocytosis; pseudocleavage involved in syncytial blastoderm formation; regulation of actin cytoskeleton organization; regulation of protein localization; sperm individualization; sperm motility; spindle organization",PF16521;PF00063;PF02736;,2.00E-96,CHOYP_MYO6.1.1,,,,,,,MYS9_DROME,Drosophila melanogaster (Fruit fly),"actin cytoskeleton organization [GO:0030036]; actin filament-based movement [GO:0030048]; actin filament organization [GO:0007015]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization involved in cell fate determination [GO:0045167]; basal protein localization [GO:0045175]; border follicle cell migration [GO:0007298]; cell-cell junction maintenance [GO:0045217]; cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte [GO:0019749]; dorsal closure [GO:0007391]; establishment of mitotic spindle localization [GO:0040001]; imaginal disc morphogenesis [GO:0007560]; larval chitin-based cuticle development [GO:0008363]; membrane organization [GO:0061024]; metamorphosis [GO:0007552]; mitochondrion transport along microtubule [GO:0047497]; morphogenesis of follicular epithelium [GO:0016333]; neuroblast division [GO:0055057]; nucleus localization [GO:0051647]; nucleus organization [GO:0006997]; oogenesis [GO:0048477]; ovarian follicle cell migration [GO:0007297]; positive regulation of exocytosis [GO:0045921]; protein localization [GO:0008104]; pseudocleavage involved in syncytial blastoderm formation [GO:0030589]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament-based process [GO:0032970]; regulation of protein localization [GO:0032880]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; sperm motility [GO:0030317]; spindle organization [GO:0007051]" comp127558_c0_seq3,1481,43.6192,0.82045492,3,0,,3.00E-30,Q9JMH9,Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain),Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain),GO:0043531; GO:0005524; GO:0007030; GO:0048194; GO:0042641; GO:0031032; GO:0016477; GO:0005856; GO:0005793; GO:0003774; GO:0016459; GO:0050714; GO:0005802,ADP binding; ATP binding; Golgi organization; Golgi vesicle budding; actomyosin; actomyosin structure organization; cell migration; cytoskeleton; endoplasmic reticulum-Golgi intermediate compartment; motor activity; myosin complex; positive regulation of protein secretion; trans-Golgi network,PF00063;PF01576;PF00595;,2.00E-172,CHOYP_MYO9.5.5,,,,,,,MY18A_MOUSE,Mus musculus (Mouse),actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714] comp127558_c0_seq4,1862,43.4479,0.82173499,2,0,,0,B2RTY4,Unconventional myosin-IXa (Unconventional myosin-9a),Unconventional myosin-IXa (Unconventional myosin-9a),GO:0005524; GO:0005096; GO:0005829; GO:0016021; GO:0046872; GO:0003774; GO:0043547; GO:0051056; GO:0007264; GO:0016461; GO:0007601,ATP binding; GTPase activator activity; cytosol; integral to membrane; metal ion binding; motor activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; unconventional myosin complex; visual perception,PF00612;PF00063;PF00788;PF00620;,0,CHOYP_LOC100870108.1.4,,,,,,,MYO9A_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; regulation of small GTPase mediated signal transduction [GO:0051056]; visual perception [GO:0007601] comp127564_c1_seq1,680,40.1471,0.50011406,18,54,,5.00E-60,O12947,Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Farnesyl cysteine carboxyl methyltransferase) (FCMT) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT),Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Farnesyl cysteine carboxyl methyltransferase) (FCMT) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT),GO:0005789; GO:0016021; GO:0004671,endoplasmic reticulum membrane; integral to membrane; protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity,PF04140;,4.00E-64,CHOYP_LOC101174897.1.1,,,,,,,ICMT_XENLA,Xenopus laevis (African clawed frog), comp127566_c0_seq1,891,39.1695,0.7769524,480,2198,,2.00E-28,A4K526,Transmembrane protein 256 homolog,Transmembrane protein 256 homolog,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF04241;,,,,,,,,,CQ061_BUFGR,Bufo gargarizans (Asian toad) (Bufo bufo gargarizans), comp127569_c0_seq1,1898,42.0969,0.34020509,0,0,,0,P53625,"Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Mannosidase-1)",,GO:0000139; GO:0005509; GO:0008340; GO:0035010; GO:0016021; GO:0004571; GO:0006486; GO:0072347,"Golgi membrane; calcium ion binding; determination of adult lifespan; encapsulation of foreign target; integral to membrane; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; protein glycosylation; response to anesthetic",,,,,,,,,,MA122_DROME,, comp127569_c0_seq2,2484,40.7407,0.38086448,16,98,,0,O60476,"Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)","Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)",GO:0000139; GO:0006491; GO:0005509; GO:0016021; GO:0048286; GO:0004571; GO:0005730; GO:0043687; GO:0018279; GO:0007585,"Golgi membrane; N-glycan processing; calcium ion binding; integral to membrane; lung alveolus development; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; nucleolus; post-translational protein modification; protein N-linked glycosylation via asparagine; respiratory gaseous exchange",PF01532;,4.00E-165,CHOYP_LOC100376162.1.1,2.00E-60,ruditapes_c6936,,,,,MA1A2_HUMAN,Homo sapiens (Human),Golgi apparatus mannose trimming [GO:1904381]; lung alveolus development [GO:0048286]; N-glycan processing [GO:0006491]; respiratory gaseous exchange [GO:0007585] comp127571_c0_seq1,991,43.3905,0.26538283,51,59,,5.00E-37,Q6P7W0,Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6),Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6),GO:0016929; GO:0003676; GO:0005634; GO:0016926; GO:0016925; GO:0006508; GO:0090234; GO:0090169; GO:0008270,SUMO-specific protease activity; nucleic acid binding; nucleus; protein desumoylation; protein sumoylation; proteolysis; regulation of kinetochore assembly; regulation of spindle assembly; zinc ion binding,PF02902;,4.00E-21,CHOYP_LOC100559910.1.2,,,,,,,SENP6_MOUSE,Mus musculus (Mouse),protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169] comp127576_c0_seq1,1493,35.2311,0.46325602,371,1634,,4.00E-91,Q962X9,Protein BUD31 homolog (Protein G10 homolog),Protein BUD31 homolog (Protein G10 homolog),GO:0005634,nucleus,PF01125;,3.00E-108,CHOYP_BUD31.3.3,9.00E-99,ruditapes2_c1611,,,,,BUD31_BRABE,Branchiostoma belcheri (Amphioxus), comp127577_c0_seq1,267,45.3184,0.37747008,18,50,,2.00E-10,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp127578_c0_seq1,562,41.9929,0.897344,31,12,,1.00E-11,P08641,Cadherin-1 (Epithelial cadherin) (E-cadherin) (Liver cell adhesion molecule) (L-CAM),Cadherin-1 (Epithelial cadherin) (E-cadherin) (Liver cell adhesion molecule) (L-CAM),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;PF08758;,,,,,,,,,CADH1_CHICK,Gallus gallus (Chicken),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp127578_c1_seq1,869,37.5144,0.62224814,49,32,,4.00E-37,Q9Y5G0,Protocadherin gamma-B5 (PCDH-gamma-B5),Protocadherin gamma-B5 (PCDH-gamma-B5),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDGH_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp127584_c0_seq1,1524,42.3228,0.7771638,2085,2822,,8.00E-164,O15990,Arginine kinase (AK) (EC 2.7.3.3),Arginine kinase (AK) (EC 2.7.3.3),GO:0005524; GO:0004054,ATP binding; arginine kinase activity,PF00217;PF02807;,3.00E-70,CHOYP_KARG.10.11,0,ruditapes2_c3369,7.00E-151,AM853323.p.cg.6,5,male gonad,KARG_LIOJA,Liolophura japonica (Chiton) (Acanthopleura japonica), comp127584_c0_seq2,1345,42.8253,0.81140105,3092,123,,5.00E-141,O15989,Arginine kinase (AK) (EC 2.7.3.3),Arginine kinase (AK) (EC 2.7.3.3),GO:0005524; GO:0004054,ATP binding; arginine kinase activity,PF00217;PF02807;,2.00E-70,CHOYP_KARG.10.11,5.00E-89,ruditapes_lrc35732,,,,,KARG_TURCO,Turbo cornutus (Horned turban) (Battilus cornutus), comp127585_c0_seq1,1377,40.5229,0.74698026,2,0,,5.00E-12,D2HQI1,Zinc finger and SCAN domain-containing protein 4,Zinc finger and SCAN domain-containing protein 4,GO:0003677; GO:0046872; GO:0000784; GO:0003700; GO:0010833; GO:0006351,"DNA binding; metal ion binding; nuclear chromosome, telomeric region; sequence-specific DNA binding transcription factor activity; telomere maintenance via telomere lengthening; transcription, DNA-dependent",PF02023;,,,,,,,,,ZSCA4_AILME,Ailuropoda melanoleuca (Giant panda),"telomere maintenance via telomere lengthening [GO:0010833]; transcription, DNA-templated [GO:0006351]" comp127585_c0_seq2,1376,40.4797,0.74895144,0,3,,9.00E-09,Q9UDV6,Zinc finger protein 212 (Zinc finger protein C2H2-150),Zinc finger protein 212 (Zinc finger protein C2H2-150),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF12417;PF01352;PF00096;PF13912;,,,,,,,,,ZN212_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp127585_c0_seq3,421,41.3302,0.84030741,8,23,,7.00E-23,Q9UJL9,Zinc finger protein ZFP69B (Zinc finger protein 643),Zinc finger protein ZFP69B (Zinc finger protein 643),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZN643_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp127586_c0_seq1,1040,42.3077,0.309881,64,34,,3.00E-50,Q68CZ1,Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein),Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein),GO:0043010; GO:0005911; GO:0005813; GO:0021549; GO:0042384; GO:0035085; GO:0022038; GO:0007368; GO:0035115; GO:0035116; GO:0007163; GO:0060322; GO:0001701; GO:0001822; GO:0021670; GO:0001889; GO:0005932; GO:0045744; GO:0021532; GO:0043584; GO:0021772; GO:0060039; GO:0008589; GO:0005923,camera-type eye development; cell-cell junction; centrosome; cerebellum development; cilium assembly; cilium axoneme; corpus callosum development; determination of left/right symmetry; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; establishment or maintenance of cell polarity; head development; in utero embryonic development; kidney development; lateral ventricle development; liver development; microtubule basal body; negative regulation of G-protein coupled receptor protein signaling pathway; neural tube patterning; nose development; olfactory bulb development; pericardium development; regulation of smoothened signaling pathway; tight junction,PF00168;PF11618;,1.00E-52,CHOYP_LOC585739.1.1,,,,,,,FTM_HUMAN,Homo sapiens (Human),camera-type eye development [GO:0043010]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; liver development [GO:0001889]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589] comp127591_c0_seq1,1358,39.2489,0.99757253,4683,7,male>female,2.00E-104,Q3SZW1,Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1),Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1),GO:0005524; GO:0001669; GO:0046872; GO:0031514; GO:0007275; GO:0004674; GO:0007286,ATP binding; acrosomal vesicle; metal ion binding; motile cilium; multicellular organismal development; protein serine/threonine kinase activity; spermatid development,PF00069;,3.00E-63,CHOYP_LOC100370380.1.1,,,,,,,TSSK1_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] comp127595_c1_seq1,900,39.3333,0.50145749,52,103,,2.00E-12,F1NVK6,Transmembrane protein 237,Transmembrane protein 237,GO:0035869; GO:0042384; GO:0016021; GO:0030111,ciliary transition zone; cilium assembly; integral to membrane; regulation of Wnt receptor signaling pathway,PF15383;,5.00E-13,CHOYP_TM237.1.1,,,,,,,TM237_CHICK,Gallus gallus (Chicken),cilium assembly [GO:0042384]; regulation of Wnt signaling pathway [GO:0030111] comp127599_c0_seq2,2364,45.8122,0.7098712,136,25,,3.00E-133,O77245,Nuclear hormone receptor E75 (Nuclear receptor subfamily 1 group D member 3),Nuclear hormone receptor E75 (Nuclear receptor subfamily 1 group D member 3),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,3.00E-128,CHOYP_E75.3.3,,,,,,,E75_METEN,Metapenaeus ensis (Greasyback shrimp) (Penaeus ensis),"transcription, DNA-templated [GO:0006351]" comp127600_c0_seq1,889,41.9573,0.61414684,32,10,,8.00E-14,Q92674,Centromere protein I (CENP-I) (FSH primary response protein 1) (Follicle-stimulating hormone primary response protein) (Interphase centromere complex protein 19) (Leucine-rich primary response protein 1),Centromere protein I (CENP-I) (FSH primary response protein 1) (Follicle-stimulating hormone primary response protein) (Interphase centromere complex protein 19) (Leucine-rich primary response protein 1),GO:0034080; GO:0005829; GO:0000776; GO:0000278; GO:0005654; GO:0007548,CENP-A containing nucleosome assembly at centromere; cytosol; kinetochore; mitotic cell cycle; nucleoplasm; sex differentiation,PF07778;,,,,,,,,,CENPI_HUMAN,Homo sapiens (Human),CENP-A containing nucleosome assembly [GO:0034080]; follicle-stimulating hormone signaling pathway [GO:0042699]; sex differentiation [GO:0007548]; sister chromatid cohesion [GO:0007062] comp127603_c0_seq1,1168,40.411,0.50431443,29,67,,3.00E-98,P57088,Transmembrane protein 33 (Protein DB83),Transmembrane protein 33 (Protein DB83) (SHINC-3),GO:0016021; GO:0042470,integral to membrane; melanosome,PF03661;,2.00E-64,CHOYP_CDC42.11.11,,,,,,,TMM33_HUMAN,Homo sapiens (Human),cellular protein localization [GO:0034613]; nuclear pore complex assembly [GO:0051292]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976] comp127604_c0_seq1,1203,32.1696,0.80530684,61,337,,5.00E-06,Q9U3W6,Protein mab-21,Protein mab-21,GO:0048568,embryonic organ development,PF03281;,,,,,,,,,MAB21_DROME,Drosophila melanogaster (Fruit fly), comp127606_c0_seq1,1150,44.7826,0.73285484,421,1372,,6.00E-46,Q9CW42,"MOSC domain-containing protein 1, mitochondrial (EC 1.-.-.-) (Mitochondrial amidoxime reducing component 1) (mARC1) (Moco sulfurase C-terminal domain-containing protein 1) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1)",Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1),GO:0016021; GO:0005743; GO:0005741; GO:0030151; GO:0016491; GO:0030170,integral to membrane; mitochondrial inner membrane; mitochondrial outer membrane; molybdenum ion binding; oxidoreductase activity; pyridoxal phosphate binding,PF03473;PF03476;,,,,,,,,,MOSC1_MOUSE,Mus musculus (Mouse),nitrate metabolic process [GO:0042126]; oxidation-reduction process [GO:0055114] comp127607_c0_seq1,532,42.8571,1.03680727,9,68,,4.00E-31,Q0IIF9,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_BOVIN,Bos taurus (Bovine), comp127615_c1_seq1,1578,45.1838,0.67967059,63,215,,4.00E-16,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127619_c0_seq1,716,36.5922,0.19181418,15,11,,,,,,,,,6.00E-24,CHOYP_LOC100373522.1.5,3.00E-19,ruditapes_c14289,,,,,,, comp127619_c0_seq3,647,34.3122,0.18881164,8,3,,,,,,,,,1.00E-12,CHOYP_LOC580130.2.2,,,,,,,,, comp127620_c0_seq1,1295,34.3629,1.10418761,47089,140090,,1.00E-07,P23038,Metallothionein (MT),Metallothionein (MT),GO:0046872,metal ion binding,,,,,,,,,,MT_CRAVI,Crassostrea virginica (Eastern oyster), comp127622_c0_seq2,938,45.629,0.72029801,0,0,,2.00E-07,P31696,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0007213; GO:0030548; GO:0005605; GO:0005509; GO:0030154; GO:0030054; GO:0035374; GO:0002162; GO:0043395; GO:0008201; GO:0016021; GO:0043236; GO:0007275; GO:0005886; GO:0032321; GO:0051491; GO:0045887; GO:0045944; GO:0043113; GO:0033691; GO:0045202; GO:0030297,G-protein coupled acetylcholine receptor signaling pathway; acetylcholine receptor regulator activity; basal lamina; calcium ion binding; cell differentiation; cell junction; chondroitin sulfate binding; dystroglycan binding; heparan sulfate proteoglycan binding; heparin binding; integral to membrane; laminin binding; multicellular organismal development; plasma membrane; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; sialic acid binding; synapse; transmembrane receptor protein tyrosine kinase activator activity,PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;,,,4.00E-12,ruditapes2_c3967,,,,,AGRIN_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113] comp127622_c0_seq3,1116,45.6093,0.84503696,0,0,,,,,,,,,,,5.00E-12,ruditapes2_c6512,,,,,,, comp127626_c1_seq1,2129,38.2339,0.54559438,0,0,,4.00E-11,A6MHQ4,Sodium/potassium-transporting ATPase subunit beta-1-interacting protein (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein) (dNKAIN),Sodium/potassium-transporting ATPase subunit beta-1-interacting protein (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein) (dNKAIN),GO:0016021; GO:0005886; GO:0002028,integral to membrane; plasma membrane; regulation of sodium ion transport,PF05640;,,,,,,,,,NKAIN_DROME,Drosophila melanogaster (Fruit fly),regulation of sodium ion transport [GO:0002028] comp127626_c1_seq2,2468,38.6953,0.58328217,0,0,,4.00E-50,Q3URJ8,Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3) (Protein FAM77D),Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3) (Protein FAM77D),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF05640;,1.00E-64,CHOYP_BRAFLDRAFT_198761.1.1,,,,,,,NKAI3_MOUSE,Mus musculus (Mouse),regulation of sodium ion transport [GO:0002028] comp127626_c1_seq4,1948,36.961,0.67524959,0,0,,2.00E-49,Q66KZ9,Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3),Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF05640;,5.00E-62,CHOYP_BRAFLDRAFT_198761.1.1,,,,,,,NKAI3_XENLA,Xenopus laevis (African clawed frog), comp127634_c0_seq1,1770,39.6045,0.9503586,26,870,,3.00E-107,Q502K2,Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-),Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-),GO:0003723; GO:0051607; GO:0045087; GO:0008152; GO:0046872; GO:0005634; GO:0008081; GO:0045088,RNA binding; defense response to virus; innate immune response; metabolic process; metal ion binding; nucleus; phosphoric diester hydrolase activity; regulation of innate immune response,PF01966;PF07647;,1.00E-18,CHOYP_SAMH1.12.12,8.00E-12,ruditapes_c985,,,,,SAMH1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; innate immune response [GO:0045087]; regulation of innate immune response [GO:0045088] comp127636_c0_seq1,927,42.8263,0.43794294,522,3758,,2.00E-116,Q9CY21,Ribosome biogenesis methyltransferase WBSCR22 (EC 2.1.1.-) (Williams-Beuren syndrome chromosomal region 22 protein homolog),Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Williams-Beuren syndrome chromosomal region 22 protein homolog),GO:0008168; GO:0005634,methyltransferase activity; nucleus,PF08241;PF12589;,4.00E-128,CHOYP_LOC581711.1.1,3.00E-77,ruditapes_c20657,,,,,WBS22_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; rRNA processing [GO:0006364]; transcription, DNA-templated [GO:0006351]" comp127641_c0_seq1,1322,31.77,0.51196223,1314,4405,,,,,,,,,7.00E-20,CHOYP_contig_025718,5.00E-32,ruditapes2_c554,,,,,,, comp127644_c0_seq1,871,36.3949,0.62753961,44,247,,1.00E-79,Q28FC1,Ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin carrier protein W) (Ubiquitin-protein ligase W),Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (Ubiquitin carrier protein W) (Ubiquitin-protein ligase W),GO:0005524; GO:0006281; GO:0071218; GO:0006515; GO:0005634; GO:0043161; GO:0006513; GO:0004842,ATP binding; DNA repair; cellular response to misfolded protein; misfolded or incompletely synthesized protein catabolic process; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein monoubiquitination; ubiquitin-protein ligase activity,PF00179;,2.00E-50,CHOYP_BRAFLDRAFT_115629.1.1,,,,,,,UBE2W_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209] comp127644_c0_seq2,740,35.5405,0.60377249,0,0,,4.00E-16,Q8LGF7,Protein PEROXIN-4 (AtPEX4) (Probable ubiquitin-conjugating enzyme E2 21) (EC 6.3.2.19) (Ubiquitin carrier protein 21),Protein PEROXIN-4 (AtPEX4) (E2 ubiquitin-conjugating enzyme 21) (Probable ubiquitin-conjugating enzyme E2 21) (EC 2.3.2.23) (Ubiquitin carrier protein 21),GO:0005524; GO:0006635; GO:0005778; GO:0016558; GO:0004842,ATP binding; fatty acid beta-oxidation; peroxisomal membrane; protein import into peroxisome matrix; ubiquitin-protein ligase activity,PF00179;,,,,,,,,,PEX4_ARATH,Arabidopsis thaliana (Mouse-ear cress),fatty acid beta-oxidation [GO:0006635]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] comp127646_c0_seq2,730,36.9863,0.94116836,19,324,,2.00E-10,Q965W1,Fatty acid-binding protein homolog 9,Fatty acid-binding protein homolog 9,GO:0008289; GO:0005215,lipid binding; transporter activity,PF00061;,,,,,,,,,FABP9_CAEEL,Caenorhabditis elegans, comp127647_c0_seq1,246,39.0244,0.88890358,26,26,,5.00E-25,O60229,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0015629; GO:0097190; GO:0005829; GO:0005085; GO:0046872; GO:0007399; GO:0048011; GO:0005543; GO:0043065; GO:0004674; GO:0035023; GO:0051056; GO:0007264; GO:0016192,ATP binding; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton; apoptotic signaling pathway; cytosol; guanyl-nucleotide exchange factor activity; metal ion binding; nervous system development; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; vesicle-mediated transport,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;,2.00E-30,CHOYP_TRIO.1.1,,,,,,,KALRN_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp127648_c0_seq1,1070,43.5514,0.35156145,17,11,,2.00E-39,Q54NA6,Myb-like protein L,Myb-like protein L,GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00249;,3.00E-17,CHOYP_LOC100546924.2.2,,,,,,,MYBL_DICDI,Dictyostelium discoideum (Slime mold),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127648_c0_seq2,856,44.743,0.38644999,0,0,,4.00E-30,P06876,Transcriptional activator Myb (Proto-oncogene c-Myb),Transcriptional activator Myb (Proto-oncogene c-Myb),GO:0030183; GO:0003677; GO:0000082; GO:0006816; GO:0003682; GO:0048566; GO:0048872; GO:0001701; GO:0005654; GO:0045944; GO:0003700; GO:0048538; GO:0006351,"B cell differentiation; DNA binding; G1/S transition of mitotic cell cycle; calcium ion transport; chromatin binding; embryonic digestive tract development; homeostasis of number of cells; in utero embryonic development; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; thymus development; transcription, DNA-dependent",PF09316;PF07988;PF00249;,,,,,,,,,MYB_MOUSE,Mus musculus (Mouse),"B cell differentiation [GO:0030183]; calcium ion transport [GO:0006816]; cellular response to interleukin-6 [GO:0071354]; chromatin remodeling [GO:0006338]; embryonic digestive tract development [GO:0048566]; G1/S transition of mitotic cell cycle [GO:0000082]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of T-helper cell differentiation [GO:0045624]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; spleen development [GO:0048536]; stem cell division [GO:0017145]; thymus development [GO:0048538]" comp127653_c2_seq1,696,39.0805,1.03560636,2,235,female>male,2.00E-12,Q9LQU4,Protein PLANT CADMIUM RESISTANCE 2 (AtPCR2),Protein PLANT CADMIUM RESISTANCE 2 (AtPCR2),GO:0016021; GO:0005886; GO:0006979,integral to membrane; plasma membrane; response to oxidative stress,PF04749;,,,,,,,,,PCR2_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to oxidative stress [GO:0006979] comp127668_c0_seq1,1015,41.0837,0.54777362,76,82,,1.00E-42,Q5BLK4,Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6),Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6),GO:0031123; GO:0050265; GO:0003676; GO:0008270,RNA 3'-end processing; RNA uridylyltransferase activity; nucleic acid binding; zinc ion binding,PF01909;PF03828;PF00098;,,,,,,,,,TUT7_MOUSE,Mus musculus (Mouse),RNA 3'-end processing [GO:0031123] comp127669_c0_seq1,538,45.3532,0.47395997,8,82,,1.00E-38,Q9C0B7,Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7),Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7),GO:0016021,integral to membrane,PF10363;PF10304;,,,,,,,,,TMCO7_HUMAN,Homo sapiens (Human), comp127673_c0_seq1,1675,42.4478,0.38762894,65,122,,3.00E-44,O60287,Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog),Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog),GO:0005730,nucleolus,PF16201;PF11707;,8.00E-14,CHOYP_URB1.2.3,,,,,,,NPA1P_HUMAN,Homo sapiens (Human), comp127677_c1_seq2,2364,40.9475,0.47548475,0,0,,5.00E-71,Q5SPL2,PHD finger protein 12 (PHD factor 1) (Pf1),PHD finger protein 12 (PHD factor 1) (Pf1),GO:0001106; GO:0016580; GO:0035091; GO:0017053; GO:0008270,RNA polymerase II transcription corepressor activity; Sin3 complex; phosphatidylinositol binding; transcriptional repressor complex; zinc ion binding,PF00628;PF16737;,8.00E-73,CHOYP_BRAFLDRAFT_89536.1.1,,,,,,,PHF12_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp127678_c1_seq1,327,44.9541,0.37904823,3,10,,4.00E-09,Q54NC8,Integrator complex subunit 1 homolog,Integrator complex subunit 1 homolog,GO:0005634,nucleus,,,,,,,,,,INT1_DICDI,Dictyostelium discoideum (Slime mold), comp127678_c1_seq3,800,44.625,0.32817574,19,0,,1.00E-85,Q6P4S8,Integrator complex subunit 1 (Int1),Integrator complex subunit 1 (Int1),GO:0034474; GO:0001833; GO:0016021; GO:0032039; GO:0043066; GO:0043154; GO:0031965; GO:0005634,U2 snRNA 3'-end processing; inner cell mass cell proliferation; integral to membrane; integrator complex; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nuclear membrane; nucleus,PF12432;,6.00E-69,CHOYP_LOC100655005.1.1,,,,,,,INT1_MOUSE,Mus musculus (Mouse),blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] comp127682_c0_seq2,1179,38.8465,0.45637409,79,47,,3.00E-09,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp127683_c0_seq1,360,29.4444,0.38775809,56,196,,,,,,,,,,,1.00E-13,ruditapes_c8059,,,,,,, comp127684_c0_seq1,396,50.2525,0.51503031,4,23,,1.00E-29,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp127688_c0_seq1,2399,33.514,0.61253847,23771,74213,,6.00E-95,Q8STF0,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,9.00E-142,CHOYP_LOC100533341.1.1,3.00E-139,ruditapes_c3243,,,,,CALM_STRIE,Strongylocentrotus intermedius (Sea urchin), comp127689_c0_seq1,1148,44.8606,0.73340481,25,187,,1.00E-151,O42422,Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH-like kinase 11) (EK11) (cEK11) (Tyrosine-protein kinase receptor CEPHA7),Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH-like kinase 11) (EK11) (cEK11) (Tyrosine-protein kinase receptor CEPHA7),GO:0005524; GO:0005004; GO:0008046; GO:0007420; GO:0048755; GO:0045499; GO:0005887; GO:0043525; GO:0070372; GO:0022407; GO:0043281; GO:0050730; GO:0031952; GO:0031290,ATP binding; GPI-linked ephrin receptor activity; axon guidance receptor activity; brain development; branching morphogenesis of a nerve; chemorepellent activity; integral to plasma membrane; positive regulation of neuron apoptotic process; regulation of ERK1 and ERK2 cascade; regulation of cell-cell adhesion; regulation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of peptidyl-tyrosine phosphorylation; regulation of protein autophosphorylation; retinal ganglion cell axon guidance,PF14575;PF01404;PF00041;PF07714;PF00536;,2.00E-139,CHOYP_EPHA7.1.1,,,,,,,EPHA7_CHICK,Gallus gallus (Chicken),apoptotic process [GO:0006915]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290] comp127689_c1_seq2,1195,45.523,0.69647936,30,120,,2.00E-07,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp127693_c0_seq1,1049,47.7598,0.82306906,202,311,,6.00E-46,P62997,"Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)","Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)",GO:0003729; GO:0000398; GO:0000166; GO:0005634; GO:0048026; GO:0000381; GO:0000302,"mRNA binding; mRNA splicing, via spliceosome; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome; response to reactive oxygen species",PF00076;,3.00E-55,CHOYP_TRA2A.1.1,,,,,,,TRA2B_RAT,Rattus norvegicus (Rat),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to reactive oxygen species [GO:0000302]" comp127694_c0_seq1,984,38.7195,1.11128904,0,841,,5.00E-79,P02594,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,2.00E-70,CHOYP_CALM.30.50,,,,,,,CALM_ELEEL,Electrophorus electricus (Electric eel) (Gymnotus electricus), comp127702_c0_seq1,1069,46.3985,0.36549098,18,64,,7.00E-131,Q7Q6S8,Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14),Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF08638;,2.00E-152,CHOYP_PHUM_PHUM128490.1.1,,,,,,,MED14_ANOGA,Anopheles gambiae (African malaria mosquito),"intracellular steroid hormone receptor signaling pathway [GO:0030518]; transcription, DNA-templated [GO:0006351]" comp127702_c0_seq2,856,46.9626,0.38186056,0,0,,3.00E-21,Q4P0P3,Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14),Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF08638;,4.00E-27,CHOYP_LOC655661.1.1,,,,,,,MED14_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),"transcription, DNA-templated [GO:0006351]" comp127710_c1_seq2,738,40.1084,0.47723691,61,90,,2.00E-50,Q5XI68,Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein),Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein),GO:0005634; GO:0006355; GO:0043565; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF00808;,1.00E-64,CHOYP_BRAFLDRAFT_68934.1.2,6.00E-104,ruditapes_c1574,,,,,NC2B_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127713_c0_seq1,847,42.7391,0.9619537,143,555,,,,,,,,,,,9.00E-14,ruditapes_c19865,,,,,,, comp127716_c0_seq1,2074,34.2816,0.56418348,19602,19699,,4.00E-15,P07746,High mobility group-T protein (HMG-T) (HMG-T1) (HMG-1),High mobility group-T protein (HMG-T) (HMG-T1) (HMG-1),GO:0003677; GO:0005694; GO:0005634,DNA binding; chromosome; nucleus,PF00505;PF09011;,5.00E-18,CHOYP_LOC778718.1.1,3.00E-63,ruditapes2_c101,,,,,HMGT_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),inflammatory response [GO:0006954] comp127717_c0_seq1,1171,41.7592,0.51533946,95,72,,7.00E-29,Q5HYC2,Uncharacterized protein KIAA2026,Uncharacterized protein KIAA2026,,,,,,,,,,,,K2026_HUMAN,Homo sapiens (Human), comp127724_c0_seq1,613,38.9886,0.6452308,16,72,,7.00E-36,Q8IYB9,Zinc finger protein 595,Zinc finger protein 595,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN595_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127724_c1_seq1,1316,36.1702,0.58250657,16,66,,2.00E-13,P18738,Gastrula zinc finger protein XlCGF9.1 (Fragment),Gastrula zinc finger protein XlCGF9.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG9_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127725_c0_seq1,1260,38.4127,0.49067047,11,7,,5.00E-144,Q5ZJJ8,Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1),Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1),GO:0005634; GO:0004721,nucleus; phosphoprotein phosphatase activity,PF03031;PF00240;,3.00E-106,CHOYP_UBCP1.1.1,,,,,,,UBCP1_CHICK,Gallus gallus (Chicken), comp127725_c0_seq2,898,39.1982,0.53230329,0,0,,1.00E-06,O94336,Uncharacterized FCP1 homology domain-containing protein C1271.03c,Uncharacterized FCP1 homology domain-containing protein C1271.03c,GO:0005829; GO:0005730; GO:0004721; GO:0005886; GO:0006470; GO:0007165,cytosol; nucleolus; phosphoprotein phosphatase activity; plasma membrane; protein dephosphorylation; signal transduction,PF03031;,,,,,,,,,YHM3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),signal transduction [GO:0007165] comp127727_c0_seq1,640,43.75,0.26427605,33,22,,,,,,,,,3.00E-33,CHOYP_LOC663019.1.1,,,,,,,,, comp127727_c1_seq1,291,40.8935,0.08463868,9,0,,,,,,,,,7.00E-18,CHOYP_LOC663019.1.1,,,,,,,,, comp127733_c0_seq3,1123,38.7355,0.73585952,60,29,,4.00E-06,Q82851,Gag-Pol polyprotein (Pr170Gag-Pol) [Cleaved into: Matrix protein p16 (MA); Capsid protein p26 (CA); Transframe peptide (p11); Protease (EC 3.4.23.-) (P119) (Retropepsin); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (P72); Integrase (IN)],Gag-Pol polyprotein (Pr170Gag-Pol) [Cleaved into: Matrix protein p16 (MA); Capsid protein p26 (CA); Transframe peptide (p11); Protease (EC 3.4.23.-) (P119) (Retropepsin); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (P72); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0004533; GO:0090305; GO:0006508; GO:0004523; GO:0039660; GO:0046718; GO:0019013; GO:0046797; GO:0008270,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; exoribonuclease H activity; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; structural constituent of virion; viral entry into host cell; viral nucleocapsid; viral procapsid maturation; zinc ion binding,PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF06817;PF00098;,2.00E-12,CHOYP_LOC100372999.1.3,,,,,,,POL_JEMBR,Jembrana disease virus (JDV),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral release from host cell [GO:0019076] comp127733_c1_seq1,499,37.2745,0.48262742,13,4,,2.00E-26,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp127736_c0_seq1,856,38.6682,0.61136225,40,100,,4.00E-78,Q5ZKX6,NEDD8-conjugating enzyme UBE2F (EC 6.3.2.-) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (Ubiquitin-conjugating enzyme E2 F),NEDD8-conjugating enzyme UBE2F (EC 6.3.2.-) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (Ubiquitin-conjugating enzyme E2 F),GO:0005524; GO:0019788; GO:0045116,ATP binding; NEDD8 ligase activity; protein neddylation,PF00179;,1.00E-84,CHOYP_UBE2F.1.1,,,,,,,UBE2F_CHICK,Gallus gallus (Chicken),postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein neddylation [GO:0045116] comp127737_c0_seq2,1071,39.9627,0.70299753,71,109,,,,,,,,,8.00E-18,CHOYP_LOC100906231.1.1,,,,,,,,, comp127743_c0_seq2,971,42.3275,0.73947266,0,0,,5.00E-13,Q9Y6U7,RING finger protein 215,RING finger protein 215,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF13639;,,,,,,,,,RN215_HUMAN,Homo sapiens (Human), comp127743_c0_seq3,1782,41.7508,0.86032019,6,0,,8.00E-58,Q6Y290,E3 ubiquitin-protein ligase RNF130 (EC 6.3.2.-) (Goliath homolog) (R-goliath) (RING finger protein 130),E3 ubiquitin-protein ligase RNF130 (EC 6.3.2.-) (Goliath homolog) (R-goliath) (RING finger protein 130),GO:0006915; GO:0005737; GO:0016021; GO:0012501; GO:0004842; GO:0008270,apoptotic process; cytoplasm; integral to membrane; programmed cell death; ubiquitin-protein ligase activity; zinc ion binding,PF02225;PF13639;,9.00E-52,CHOYP_RN150.1.1,,,,,,,GOLI_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; programmed cell death [GO:0012501] comp127744_c0_seq1,1047,41.7383,0.2983012,1,5,,2.00E-10,Q835R5,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,3.00E-16,CHOYP_LOC100377265.2.2,4.00E-26,ruditapes_c23056,,,,,DNAJ_ENTFA,Enterococcus faecalis (strain ATCC 700802 / V583),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp127744_c0_seq2,1064,41.7293,0.31549574,4,5,,,,,,,,,5.00E-20,CHOYP_DNJB5.1.1,,,,,,,,, comp127745_c0_seq1,1032,41.7636,0.68964617,67,90,,2.00E-50,Q6UVM3,Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1),Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1),GO:0005524; GO:0015269; GO:0005249; GO:0008076,ATP binding; calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,3.00E-36,CHOYP_PHUM_PHUM562900.1.1,,,,,,,KCNT2_HUMAN,Homo sapiens (Human), comp127750_c0_seq1,885,42.9379,0.82661042,31,171,,9.00E-52,P51658,Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),GO:0004303; GO:0001701; GO:0016021; GO:0001890; GO:0032526; GO:0006694; GO:0047035,estradiol 17-beta-dehydrogenase activity; in utero embryonic development; integral to membrane; placenta development; response to retinoic acid; steroid biosynthetic process; testosterone dehydrogenase (NAD+) activity,PF00106;,,,,,,,,,DHB2_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694] comp127752_c0_seq1,601,43.594,0.43557552,80,599,,8.00E-32,Q3KRG3,Pre-rRNA-processing protein TSR2 homolog,Pre-rRNA-processing protein TSR2 homolog,GO:0006364,rRNA processing,PF10273;,5.00E-24,CHOYP_BRAFLDRAFT_215413.1.1,,,,,,,TSR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp127753_c0_seq1,2104,40.1616,0.5797726,4372,55,,1.00E-59,Q8IYX7,Protein FAM154A,Stabilizer of axonemal microtubules 1,,,,,,,,,,,,F154A_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; cellular response to cold [GO:0070417]; cold acclimation [GO:0009631]; positive regulation of cilium assembly [GO:0045724] comp127755_c0_seq1,1232,43.9123,0.52911164,33,88,,2.00E-105,Q17DK5,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0009882; GO:0005737; GO:0050660; GO:0045892; GO:0005641; GO:0048471; GO:0000060; GO:0018298; GO:0042752; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; blue light photoreceptor activity; cytoplasm; flavin adenine dinucleotide binding; negative regulation of transcription, DNA-dependent; nuclear envelope lumen; perinuclear region of cytoplasm; protein import into nucleus, translocation; protein-chromophore linkage; regulation of circadian rhythm; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,1.00E-86,CHOYP_CRY1.1.2,,,,,,,CRY1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; protein import into nucleus, translocation [GO:0000060]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp127757_c1_seq1,787,46.2516,0.29579627,59,43,,5.00E-99,P16393,3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34),3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34),GO:0050661; GO:0006695; GO:0015936; GO:0005789; GO:0004420; GO:0016021; GO:0008299,NADP binding; cholesterol biosynthetic process; coenzyme A metabolic process; endoplasmic reticulum membrane; hydroxymethylglutaryl-CoA reductase (NADPH) activity; integral to membrane; isoprenoid biosynthetic process,PF00368;PF12349;,,,,,,,,,HMDH_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cholesterol biosynthetic process [GO:0006695]; coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299]; sterol biosynthetic process [GO:0016126] comp127757_c2_seq1,1013,42.4482,0.41682393,62,82,,2.00E-100,P54960,3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34),3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34),GO:0050661; GO:0015936; GO:0005789; GO:0004420; GO:0016021; GO:0008299,NADP binding; coenzyme A metabolic process; endoplasmic reticulum membrane; hydroxymethylglutaryl-CoA reductase (NADPH) activity; integral to membrane; isoprenoid biosynthetic process,PF00368;PF12349;,2.00E-95,CHOYP_BRAFLDRAFT_57278.1.1,,,,,,,HMDH_BLAGE,Blattella germanica (German cockroach) (Blatta germanica),coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299] comp127758_c1_seq2,437,44.6224,0.42690282,11,43,,7.00E-62,Q9Y4B4,Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2),Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2),GO:0005524; GO:0003677; GO:0004386; GO:0005634; GO:0003712,ATP binding; DNA binding; helicase activity; nucleus; transcription cofactor activity,PF00271;PF00176;,1.00E-55,CHOYP_ARIP4.3.3,,,,,,,ARIP4_HUMAN,Homo sapiens (Human), comp127759_c0_seq3,1064,34.3045,0.4162161,0,0,,1.00E-20,Q9H633,Ribonuclease P protein subunit p21 (RNaseP protein p21) (EC 3.1.26.5) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V),Ribonuclease P protein subunit p21 (RNaseP protein p21) (EC 3.1.26.5) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V),GO:0005730; GO:0042493; GO:0004526; GO:0008033,nucleolus; response to drug; ribonuclease P activity; tRNA processing,PF04032;,,,,,,,,,RPP21_HUMAN,Homo sapiens (Human),response to drug [GO:0042493]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] comp127763_c0_seq2,576,43.2292,0.81596206,5,5,,4.00E-24,Q0VD32,cAMP-responsive element-binding protein-like 2,cAMP-responsive element-binding protein-like 2,GO:0030154; GO:0019048; GO:0005634; GO:0045600; GO:0046326; GO:0046889; GO:0033138; GO:0045893; GO:0050821; GO:0043565; GO:0003700; GO:0006351,"cell differentiation; modulation by virus of host morphology or physiology; nucleus; positive regulation of fat cell differentiation; positive regulation of glucose import; positive regulation of lipid biosynthetic process; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription, DNA-dependent; protein stabilization; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF07716;,,,,,,,,,CRBL2_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glucose import [GO:0046326]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription, DNA-templated [GO:0045893]; protein stabilization [GO:0050821]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp127766_c0_seq1,925,45.4054,0.42157068,37,109,,1.00E-43,O09053,Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-),Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-),GO:0008408; GO:0005524; GO:0043140; GO:0006310; GO:0006260; GO:0000731; GO:0051880; GO:0032389; GO:0000403; GO:0006284; GO:0000405; GO:0071480; GO:0009267; GO:0005813; GO:0006302; GO:0009378; GO:0000287; GO:0030145; GO:0010259; GO:0005730; GO:0032066; GO:0005654; GO:0051345; GO:0042981; GO:0040009; GO:0031297; GO:0001302; GO:0010225; GO:0006979; GO:0000723,3'-5' exonuclease activity; ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA recombination; DNA replication; DNA synthesis involved in DNA repair; G-quadruplex DNA binding; MutLalpha complex; Y-form DNA binding; base-excision repair; bubble DNA binding; cellular response to gamma radiation; cellular response to starvation; centrosome; double-strand break repair; four-way junction helicase activity; magnesium ion binding; manganese ion binding; multicellular organismal aging; nucleolus; nucleolus to nucleoplasm transport; nucleoplasm; positive regulation of hydrolase activity; regulation of apoptotic process; regulation of growth rate; replication fork processing; replicative cell aging; response to UV-C; response to oxidative stress; telomere maintenance,PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;,,,,,,,,,WRN_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp127766_c3_seq1,553,47.7396,0.41526977,13,54,,5.00E-73,Q14191,"Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)","Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)",GO:0043138; GO:0008408; GO:0005524; GO:0043140; GO:0004003; GO:0006310; GO:0000731; GO:0051880; GO:0000403; GO:0006284; GO:0000405; GO:0007569; GO:0071480; GO:0009267; GO:0005813; GO:0006302; GO:0009378; GO:0000287; GO:0030145; GO:0010259; GO:0005730; GO:0032066; GO:0005654; GO:0051345; GO:0032403; GO:0042803; GO:0042981; GO:0040009; GO:0031297; GO:0001302; GO:0010225; GO:0006979; GO:0000723,3'-5' DNA helicase activity; 3'-5' exonuclease activity; ATP binding; ATP-dependent 3'-5' DNA helicase activity; ATP-dependent DNA helicase activity; DNA recombination; DNA synthesis involved in DNA repair; G-quadruplex DNA binding; Y-form DNA binding; base-excision repair; bubble DNA binding; cell aging; cellular response to gamma radiation; cellular response to starvation; centrosome; double-strand break repair; four-way junction helicase activity; magnesium ion binding; manganese ion binding; multicellular organismal aging; nucleolus; nucleolus to nucleoplasm transport; nucleoplasm; positive regulation of hydrolase activity; protein complex binding; protein homodimerization activity; regulation of apoptotic process; regulation of growth rate; replication fork processing; replicative cell aging; response to UV-C; response to oxidative stress; telomere maintenance,PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;,5.00E-49,CHOYP_LOC100179894.1.1,,,,,,,WRN_HUMAN,Homo sapiens (Human),aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; protein sumoylation [GO:0016925]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp127772_c0_seq2,589,39.8981,0.56672248,0,0,,1.00E-14,P27816,Microtubule-associated protein 4 (MAP-4),Microtubule-associated protein 4 (MAP-4),GO:0051301; GO:0005737; GO:0051294; GO:0005874; GO:0005875; GO:0051012; GO:0072686; GO:0007052; GO:0005886; GO:0005198,cell division; cytoplasm; establishment of spindle orientation; microtubule; microtubule associated complex; microtubule sliding; mitotic spindle; mitotic spindle organization; plasma membrane; structural molecule activity,PF00418;,,,,,,,,,MAP4_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; establishment of spindle orientation [GO:0051294]; microtubule sliding [GO:0051012]; mitotic spindle organization [GO:0007052]; negative regulation of nonmotile primary cilium assembly [GO:1902856]; neuron projection development [GO:0031175] comp127772_c0_seq4,571,41.5061,0.58452734,0,0,,9.00E-18,Q9MYX8,Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau),Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau),GO:0030424; GO:0005829; GO:0005874; GO:0005886,axon; cytosol; microtubule; plasma membrane,PF00418;,,,,,,,,,TAU_PAPHA,Papio hamadryas (Hamadryas baboon), comp127789_c1_seq1,705,39.2908,0.89057259,7,144,,3.00E-10,Q8JFG3,Tumor necrosis factor (TNF-alpha),Tumor necrosis factor (TNF-alpha),GO:0005615; GO:0006955; GO:0016021,extracellular space; immune response; integral to membrane,PF00229;,,,,,,,,,TNFA_SPAAU,Sparus aurata (Gilthead sea bream),immune response [GO:0006955] comp127791_c1_seq2,619,43.2956,0.65910874,16,0,,,,,,,,,1.00E-12,CHOYP_LOC100368070.1.1,,,,,,,,, comp127792_c1_seq1,1171,43.9795,0.42521573,24,138,,2.00E-119,Q9VH78,"Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (EC 2.4.1.260) (Asparagine-linked glycosylation protein 12 homolog) (Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase) (Mannosyltransferase ALG12 homolog)","Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (EC 2.4.1.260) (Asparagine-linked glycosylation protein 12 homolog) (Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase) (Mannosyltransferase ALG12 homolog)",GO:0000009; GO:0052917; GO:0006488; GO:0005783; GO:0005789; GO:0016021; GO:0006486,"alpha-1,6-mannosyltransferase activity; dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity; dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein glycosylation",PF03901;,,,,,,,,,ALG12_DROME,Drosophila melanogaster (Fruit fly),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487] comp127794_c0_seq1,1571,39.338,0.54559818,43,222,,5.00E-32,Q63767,Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas),Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas),GO:0050853; GO:0007186; GO:0007015; GO:0007155; GO:0016477; GO:0005737; GO:0007173; GO:0005925; GO:0008286; GO:0007229; GO:0048011; GO:0005886; GO:0048008; GO:0030335; GO:0001726,B cell receptor signaling pathway; G-protein coupled receptor signaling pathway; actin filament organization; cell adhesion; cell migration; cytoplasm; epidermal growth factor receptor signaling pathway; focal adhesion; insulin receptor signaling pathway; integrin-mediated signaling pathway; neurotrophin TRK receptor signaling pathway; plasma membrane; platelet-derived growth factor receptor signaling pathway; positive regulation of cell migration; ruffle,PF12026;PF08824;PF00018;,7.00E-46,CHOYP_LOC100374152.1.1,,,,,,,BCAR1_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; epidermal growth factor receptor signaling pathway [GO:0007173]; G-protein coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335] comp127796_c0_seq1,1567,36.6943,1.17874772,33,495,,1.00E-13,Q9LDH0,"Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)","Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)",GO:0032580; GO:0005797; GO:0000139; GO:0050513; GO:0016021; GO:0031204; GO:0006487,"Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; glycoprotein 2-beta-D-xylosyltransferase activity; integral to membrane; posttranslational protein targeting to membrane, translocation; protein N-linked glycosylation",PF04577;,,,,,,,,,XYLT_ARATH,Arabidopsis thaliana (Mouse-ear cress),"posttranslational protein targeting to membrane, translocation [GO:0031204]; protein N-linked glycosylation [GO:0006487]" comp127797_c0_seq1,446,40.583,0.2202524,40,12,,3.00E-12,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp127798_c1_seq1,925,43.2432,0.7410973,1,201,female>male,1.00E-06,P11464,Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (CD antigen CD66f),Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (CD antigen CD66f),GO:0005576; GO:0007565,extracellular region; female pregnancy,PF13895;PF07686;,,,,,,,,,PSG1_HUMAN,Homo sapiens (Human),female pregnancy [GO:0007565] comp127801_c0_seq1,830,35.4217,0.61555645,1207,3402,,2.00E-13,Q99N85,"28S ribosomal protein S18a, mitochondrial (MRP-S18-a) (Mrps18a) (S18mt-a) (28S ribosomal protein S18-3, mitochondrial) (MRP-S18-3)","28S ribosomal protein S18a, mitochondrial (MRP-S18-a) (Mrps18a) (S18mt-a) (28S ribosomal protein S18-3, mitochondrial) (MRP-S18-3)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF01084;,,,2.00E-41,ruditapes_lrc35446,,,,,RT18A_MOUSE,Mus musculus (Mouse),mitochondrial translation [GO:0032543] comp127806_c0_seq1,1389,35.5652,0.3428545,0,0,,,,,,,,,1.00E-60,CHOYP_LOC100118502.1.1,,,,,,,,, comp127806_c0_seq3,1686,35.8244,0.44629645,0,0,,5.00E-94,Q9DCR2,AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adapter-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a),AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a),GO:0030123; GO:0005794; GO:0008089; GO:0048490; GO:0030659; GO:0006886; GO:0008565; GO:0005802,AP-3 adaptor complex; Golgi apparatus; anterograde axon cargo transport; anterograde synaptic vesicle transport; cytoplasmic vesicle membrane; intracellular protein transport; protein transporter activity; trans-Golgi network,PF01217;,,,3.00E-81,ruditapes_c10304,,,,,AP3S1_MOUSE,Mus musculus (Mouse),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp127806_c0_seq5,1779,35.5818,0.49984972,0,0,,1.00E-93,Q9DCR2,AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adapter-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a),AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a),GO:0030123; GO:0005794; GO:0008089; GO:0048490; GO:0030659; GO:0006886; GO:0008565; GO:0005802,AP-3 adaptor complex; Golgi apparatus; anterograde axon cargo transport; anterograde synaptic vesicle transport; cytoplasmic vesicle membrane; intracellular protein transport; protein transporter activity; trans-Golgi network,PF01217;,9.00E-115,CHOYP_LOC100118502.1.1,,,,,,,AP3S1_MOUSE,Mus musculus (Mouse),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp127808_c0_seq1,2126,43.2738,1.02670494,4207,95,,1.00E-129,A6H782,Tektin-3,Tektin-3,GO:0035085; GO:0005874; GO:0000226,cilium axoneme; microtubule; microtubule cytoskeleton organization,,0,CHOYP_TEKT3.1.1,,,,,,,TEKT3_BOVIN,Bos taurus (Bovine),cilium morphogenesis [GO:0060271]; regulation of fertilization [GO:0080154]; sperm motility [GO:0030317] comp127811_c0_seq1,1022,40.1174,0.83049672,21,2680,female>male,2.00E-14,O08573,Galectin-9 (Gal-9),Galectin-9 (Gal-9),GO:0030246; GO:0005737; GO:0005576; GO:0016936; GO:0007157,carbohydrate binding; cytoplasm; extracellular region; galactoside binding; heterophilic cell-cell adhesion,PF00337;,,,,,,,,,LEG9_MOUSE,Mus musculus (Mouse),"cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune system process [GO:0002376]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]" comp127812_c0_seq1,589,37.3514,0.97722849,34,377,,2.00E-20,Q66IM5,Protein GTLF3B,Protein NATD1 (N-acetyltransferase domain-containing protein 1),,,PF14542;,,,1.00E-23,ruditapes_c7539,,,,,GTL3B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp127816_c0_seq1,1252,46.0863,0.29621768,44,46,,2.00E-55,O15040,Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297),Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297),GO:0006914; GO:0008219,autophagy; cell death,PF06462;,5.00E-15,CHOYP_BRAFLDRAFT_216841.4.4,,,,,,,TCPR2_HUMAN,Homo sapiens (Human),autophagy [GO:0006914] comp127828_c0_seq1,1071,45.2848,0.52892383,33,75,,6.00E-08,Q8IZA0,Dyslexia-associated protein KIAA0319-like protein,Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR),GO:0031410; GO:0016021,cytoplasmic vesicle; integral to membrane,,,,,,,,,,K319L_HUMAN,Homo sapiens (Human), comp127834_c0_seq4,468,43.3761,0.69174357,0,0,,1.00E-07,Q6GQN5,Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67),Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67),GO:0003779; GO:0005813; GO:0005737; GO:0045502; GO:0002177; GO:0015631,actin binding; centrosome; cytoplasm; dynein binding; manchette; tubulin binding,PF13855;,,,,,,,,,PPR42_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of phosphatase activity [GO:0010921] comp127834_c1_seq1,229,37.1179,0.40210557,4,6,,7.00E-13,Q6GQN5,Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67),Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67),GO:0003779; GO:0005813; GO:0005737; GO:0045502; GO:0002177; GO:0015631,actin binding; centrosome; cytoplasm; dynein binding; manchette; tubulin binding,PF13855;,,,,,,,,,PPR42_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of phosphatase activity [GO:0010921] comp127836_c0_seq1,382,42.1466,0.41450501,8,10,,1.00E-58,P51112,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0005737; GO:0005634; GO:0048513; GO:0008134,cytoplasm; nucleus; organ development; transcription factor binding,PF12372;,2.00E-57,CHOYP_HD.1.1,,,,,,,HD_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),animal organ development [GO:0048513] comp127845_c1_seq1,718,38.3008,0.90336677,9,95,,1.00E-20,P45961,Calexcitin-2,Calexcitin-2,GO:0005509,calcium ion binding,,6.00E-49,CHOYP_AAEL_AAEL010792.2.2,,,,,,,CEX2_CAEEL,Caenorhabditis elegans, comp127848_c1_seq2,802,44.8878,0.32219186,2,0,,3.00E-25,Q9VE34,Ectopic P granules protein 5 homolog,Ectopic P granules protein 5 homolog,GO:0006914; GO:0046331,autophagy; lateral inhibition,,,,,,,,,,EPG5_DROME,Drosophila melanogaster (Fruit fly),autophagosome maturation [GO:0097352]; lateral inhibition [GO:0046331] comp127848_c3_seq2,1031,44.7139,0.44675367,20,13,,1.00E-42,Q9HCE0,Ectopic P granules protein 5 homolog,Ectopic P granules protein 5 homolog,GO:0006914,autophagy,,,,,,,,,,EPG5_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; endocytic recycling [GO:0032456] comp127848_c3_seq3,533,42.5891,0.37342789,3,0,,,,,,,,,3.00E-13,CHOYP_EPG5.1.1,,,,,,,,, comp127852_c2_seq1,419,43.1981,0.77036389,15,11,,9.00E-29,Q7KHG2,Zinc finger protein jing (Zinc finger protein rhumba),Zinc finger protein jing (Zinc finger protein rhumba),GO:0035098; GO:0007411; GO:0007298; GO:0016568; GO:0008347; GO:0007474; GO:0007479; GO:0046872; GO:0000122; GO:0003676; GO:0007424; GO:0007382; GO:0042246; GO:0006351; GO:0007418,"ESC/E(Z) complex; axon guidance; border follicle cell migration; chromatin modification; glial cell migration; imaginal disc-derived wing vein specification; leg disc proximal/distal pattern formation; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleic acid binding; open tracheal system development; specification of segmental identity, maxillary segment; tissue regeneration; transcription, DNA-dependent; ventral midline development",,,,,,,,,,JING_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; central nervous system development [GO:0007417]; chromatin modification [GO:0016568]; glial cell migration [GO:0008347]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; leg disc proximal/distal pattern formation [GO:0007479]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; open tracheal system development [GO:0007424]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; specification of segmental identity, maxillary segment [GO:0007382]; tissue regeneration [GO:0042246]; transcription, DNA-templated [GO:0006351]; ventral midline development [GO:0007418]" comp127861_c0_seq1,1982,34.3088,0.47908849,113,84,,3.00E-40,O35261,Transcription factor E2F3 (E2F-3),Transcription factor E2F3 (E2F-3),GO:0003677; GO:0007049; GO:0001047; GO:0005634; GO:0008284; GO:0045893; GO:0003700; GO:0005667; GO:0006351,"DNA binding; cell cycle; core promoter binding; nucleus; positive regulation of cell proliferation; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF16421;PF02319;,1.00E-38,CHOYP_E2F3.1.1,,,,,,,E2F3_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp127866_c0_seq1,806,43.3002,0.49529536,4,7,,,,,,,,,1.00E-135,CHOYP_MADD.1.3,,,,,,,,, comp127866_c0_seq2,770,42.987,0.49897297,4,0,,2.00E-113,Q9VXY2,MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor),MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor),GO:0017112; GO:0000187; GO:0006915; GO:0016021; GO:0007269; GO:0051726; GO:1902041; GO:0008021; GO:0016192,Rab guanyl-nucleotide exchange factor activity; activation of MAPK activity; apoptotic process; integral to membrane; neurotransmitter secretion; regulation of cell cycle; regulation of extrinsic apoptotic signaling pathway via death domain receptors; synaptic vesicle; vesicle-mediated transport,PF02141;PF03456;,3.00E-155,CHOYP_MADD.3.3,,,,,,,MADD_DROME,Drosophila melanogaster (Fruit fly),activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; neurotransmitter secretion [GO:0007269]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; vesicle-mediated transport [GO:0016192] comp127891_c0_seq1,1631,41.9375,0.45095347,41,140,,2.00E-138,Q3UFS0,Protein zyg-11 homolog B,Protein zyg-11 homolog B,,,,,,,,,,,,ZY11B_MOUSE,Mus musculus (Mouse),regulation of ubiquitin-protein transferase activity [GO:0051438] comp127891_c0_seq3,899,43.3815,0.49751305,3,0,,,,,,,,,3.00E-79,CHOYP_ISCW_ISCW018108.1.1,,,,,,,,, comp127899_c0_seq3,1131,43.9434,0.69200258,75,14,,,,,,,,,3.00E-11,CHOYP_TVAG_087170.6.8,,,,,,,,, comp127902_c0_seq1,1324,45.3172,0.32459597,5,4,,0,Q32PW3,Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),GO:0008237; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"metallopeptidase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01433;,3.00E-100,CHOYP_LOC100706922.1.1,,,,,,,TAF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp127902_c0_seq2,1285,44.5136,0.33036095,4,0,,7.00E-09,P95928,Leucyl aminopeptidase (EC 3.4.11.1),Leucyl aminopeptidase (EC 3.4.11.1),GO:0004177; GO:0005737; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; metallopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,APE2_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2),peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp127903_c0_seq1,1725,33.6812,0.49118996,275,2442,,2.00E-43,Q9D0B6,Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1),Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1),,,PF04669;,2.00E-21,CHOYP_LOC100368495.1.1,,,,,,,CX026_MOUSE,Mus musculus (Mouse), comp127905_c0_seq2,1442,29.7503,0.50642709,14,34,,,,,,,,,4.00E-11,CHOYP_MYO9.4.5,,,,,,,,, comp127914_c0_seq1,1344,38.244,0.71380955,2172,5,male>female,2.00E-08,Q8JL69,Kelch repeat and BTB domain-containing protein 1,Kelch repeat and BTB domain-containing protein 1,GO:0030430; GO:0039649,host cell cytoplasm; modulation by virus of host ubiquitin-protein ligase activity,PF07707;PF00651;PF01344;,,,,,,,,,KBTB1_ECTVM,Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus),modulation by virus of host ubiquitin-protein ligase activity [GO:0039649] comp127916_c0_seq1,284,44.0141,0.96636566,7,109,,6.00E-08,Q5FVR2,Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase),Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase),GO:0004645; GO:0006206; GO:0006213; GO:0016154; GO:0009032,phosphorylase activity; pyrimidine nucleobase metabolic process; pyrimidine nucleoside metabolic process; pyrimidine-nucleoside phosphorylase activity; thymidine phosphorylase activity,PF02885;PF00591;PF07831;,,,9.00E-27,ruditapes_c12778,,,,,TYPH_RAT,Rattus norvegicus (Rat),pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleotide metabolic process [GO:0006220] comp127917_c0_seq1,280,31.0714,0.29893998,19,137,,,,,,,,,,,2.00E-23,ruditapes_c13333,,,,,,, comp127919_c0_seq2,611,35.6792,0.56968926,7,37,,4.00E-42,Q28BZ2,Histidine triad nucleotide-binding protein 3 (HINT-3) (EC 3.-.-.-),Histidine triad nucleotide-binding protein 3 (HINT-3) (EC 3.-.-.-),GO:0005737; GO:0016787; GO:0008152; GO:0000166; GO:0005634,cytoplasm; hydrolase activity; metabolic process; nucleotide binding; nucleus,,,,,,,,,,HINT3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp127928_c0_seq2,782,42.3274,0.46382897,0,0,,7.00E-68,Q8BFR6,AN1-type zinc finger protein 1,AN1-type zinc finger protein 1,GO:0008270,zinc ion binding,PF01428;,,,,,,,,,ZFAN1_MOUSE,Mus musculus (Mouse), comp127928_c0_seq3,378,39.9471,0.47460082,0,0,,2.00E-14,Q8N6M9,AN1-type zinc finger protein 2A,AN1-type zinc finger protein 2A,GO:0005737; GO:0005634; GO:0008270,cytoplasm; nucleus; zinc ion binding,PF01428;,,,,,,,,,ZFN2A_HUMAN,Homo sapiens (Human),cellular response to arsenic-containing substance [GO:0071243]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436] comp127928_c0_seq5,723,43.7068,0.44141043,0,0,,5.00E-06,Q4KLG9,AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein),AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein),GO:0005783; GO:0008270,endoplasmic reticulum; zinc ion binding,PF01428;,,,,,,,,,ZFN2B_RAT,Rattus norvegicus (Rat),"SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]" comp127932_c0_seq3,710,33.2394,0.36183278,65,51,,1.00E-13,Q9P0U1,Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog),Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog),GO:0044267; GO:0016021; GO:0005742; GO:0030150; GO:0006626; GO:0008320,cellular protein metabolic process; integral to membrane; mitochondrial outer membrane translocase complex; protein import into mitochondrial matrix; protein targeting to mitochondrion; protein transmembrane transporter activity,PF08038;,,,,,,,,,TOM7_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein import into mitochondrial matrix [GO:0030150]; protein import into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of protein stability [GO:0031647] comp127932_c0_seq4,738,32.1138,0.37398854,58,242,,1.00E-13,Q9P0U1,Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog),Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog),GO:0044267; GO:0016021; GO:0005742; GO:0030150; GO:0006626; GO:0008320,cellular protein metabolic process; integral to membrane; mitochondrial outer membrane translocase complex; protein import into mitochondrial matrix; protein targeting to mitochondrion; protein transmembrane transporter activity,PF08038;,,,2.00E-20,ruditapes2_c5995,,,,,TOM7_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein import into mitochondrial matrix [GO:0030150]; protein import into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of protein stability [GO:0031647] comp127946_c0_seq2,1071,38.6555,0.85260548,26,149,,4.00E-66,Q66IM1,Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R),Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R),GO:0000247; GO:0005789; GO:0006696; GO:0016021; GO:0006869; GO:0005637; GO:0005640; GO:0005886,C-8 sterol isomerase activity; endoplasmic reticulum membrane; ergosterol biosynthetic process; integral to membrane; lipid transport; nuclear inner membrane; nuclear outer membrane; plasma membrane,PF04622;,1.00E-33,CHOYP_LOC100313693.2.2,,,,,,,SGMR1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),lipid transport [GO:0006869] comp127961_c1_seq1,2051,41.9308,0.49156402,101,74,,2.00E-10,P15822,Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1),Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1),GO:0003677; GO:0005737; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",,,,,,,,,,ZEP1_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366] comp127962_c0_seq1,559,37.2093,1.24675724,30,92,,2.00E-11,Q66S54,Mannose-binding protein C (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin),Mannose-binding protein C (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin),GO:0005581; GO:0006958; GO:0001867; GO:0005537,"collagen; complement activation, classical pathway; complement activation, lectin pathway; mannose binding",PF01391;PF00059;,,,,,,,,,MBL2_HYLLA,Hylobates lar (Common gibbon) (White-handed gibbon),"complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]" comp127967_c2_seq1,1641,40.3413,0.56593284,0,4,,2.00E-56,O08586,"Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)","Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)",GO:0030165; GO:0016605; GO:0043220; GO:0007092; GO:0001525; GO:0006915; GO:0060070; GO:0048738; GO:0032286; GO:0021955; GO:0005737; GO:0060997; GO:0021542; GO:0043542; GO:0048853; GO:0046855; GO:0051717; GO:0009898; GO:0007611; GO:0045475; GO:0060291; GO:0000287; GO:0060179; GO:0042711; GO:0033555; GO:0035749; GO:0043066; GO:0050771; GO:0090344; GO:0030336; GO:0045792; GO:0031658; GO:0061002; GO:0050680; GO:0090394; GO:0051895; GO:0031642; GO:0046621; GO:0051898; GO:0090071; GO:2000808; GO:0043005; GO:0007270; GO:0005634; GO:0046856; GO:0016314; GO:0051800; GO:0004438; GO:2001235; GO:0008284; GO:2000463; GO:2000060; GO:0051091; GO:0097107; GO:0060134; GO:0097105; GO:0060736; GO:0043491; GO:0004722; GO:0050821; GO:0004725; GO:0008138; GO:0002902; GO:0033032; GO:0031647; GO:0060024; GO:0035176; GO:0060074,"PDZ domain binding; PML body; Schmidt-Lanterman incisure; activation of mitotic anaphase-promoting complex activity; angiogenesis; apoptotic process; canonical Wnt receptor signaling pathway; cardiac muscle tissue development; central nervous system myelin maintenance; central nervous system neuron axonogenesis; cytoplasm; dendritic spine morphogenesis; dentate gyrus development; endothelial cell migration; forebrain morphogenesis; inositol phosphate dephosphorylation; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; internal side of plasma membrane; learning or memory; locomotor rhythm; long-term synaptic potentiation; magnesium ion binding; male mating behavior; maternal behavior; multicellular organismal response to stress; myelin sheath adaxonal region; negative regulation of apoptotic process; negative regulation of axonogenesis; negative regulation of cell aging; negative regulation of cell migration; negative regulation of cell size; negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; negative regulation of dendritic spine morphogenesis; negative regulation of epithelial cell proliferation; negative regulation of excitatory postsynaptic membrane potential; negative regulation of focal adhesion assembly; negative regulation of myelination; negative regulation of organ growth; negative regulation of protein kinase B signaling cascade; negative regulation of ribosome biogenesis; negative regulation of synaptic vesicle clustering; neuron projection; neuron-neuron synaptic transmission; nucleus; phosphatidylinositol dephosphorylation; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; positive regulation of apoptotic signaling pathway; positive regulation of cell proliferation; positive regulation of excitatory postsynaptic membrane potential; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of sequence-specific DNA binding transcription factor activity; postsynaptic density assembly; prepulse inhibition; presynaptic membrane assembly; prostate gland growth; protein kinase B signaling cascade; protein serine/threonine phosphatase activity; protein stabilization; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of B cell apoptotic process; regulation of myeloid cell apoptotic process; regulation of protein stability; rhythmic synaptic transmission; social behavior; synapse maturation",PF00782;PF10409;,2.00E-73,CHOYP_LOC752773.1.2,,,,,,,PTEN_MOUSE,Mus musculus (Mouse),"adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031658]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myelination [GO:0031642]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of synaptic vesicle clustering [GO:2000808]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]" comp127967_c2_seq2,1630,40.4294,0.56763006,2,36,,5.00E-116,Q6XPS3,"Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)","Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)",GO:0000139; GO:0005789; GO:0016021; GO:0005216; GO:0035335; GO:0006661; GO:0016314; GO:0004725; GO:0008138; GO:0044281,"Golgi membrane; endoplasmic reticulum membrane; integral to membrane; ion channel activity; peptidyl-tyrosine dephosphorylation; phosphatidylinositol biosynthetic process; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; small molecule metabolic process",PF00782;PF10409;,8.00E-52,CHOYP_LOC101074730.1.1,,,,,,,TPTE2_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661] comp127974_c0_seq1,959,32.951,0.6233773,467,2283,,2.00E-18,Q90YI5,Mitochondrial import inner membrane translocase subunit Tim8 A,Mitochondrial import inner membrane translocase subunit Tim8 A,GO:0046872; GO:0005743; GO:0015031,metal ion binding; mitochondrial inner membrane; protein transport,PF02953;,,,4.00E-12,ruditapes_c8023,,,,,TIM8A_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),protein transport [GO:0015031] comp127977_c0_seq1,1212,41.0891,0.91604344,19,475,,,,,,,,,1.00E-21,CHOYP_LOC100159027.1.2,2.00E-12,ruditapes_c11516,,,,,,, comp127987_c1_seq1,1174,39.0971,0.35095605,65,135,,2.00E-129,P28663,Beta-soluble NSF attachment protein (SNAP-beta) (Brain protein I47) (N-ethylmaleimide-sensitive factor attachment protein beta),Beta-soluble NSF attachment protein (SNAP-beta) (Brain protein I47) (N-ethylmaleimide-sensitive factor attachment protein beta),GO:0035494; GO:0006886; GO:0010807; GO:0035249; GO:0070044; GO:0019905,"SNARE complex disassembly; intracellular protein transport; regulation of synaptic vesicle priming; synaptic transmission, glutamatergic; synaptobrevin 2-SNAP-25-syntaxin-1a complex; syntaxin binding",,2.00E-127,CHOYP_BRAFLDRAFT_114106.1.1,,,,,,,SNAB_MOUSE,Mus musculus (Mouse),"intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; regulation of synaptic vesicle priming [GO:0010807]; SNARE complex disassembly [GO:0035494]; synaptic transmission, glutamatergic [GO:0035249]" comp127991_c1_seq2,747,39.0897,0.42349687,29,45,,5.00E-44,Q6P6S4,Nucleotide exchange factor SIL1,Nucleotide exchange factor SIL1,GO:0005788; GO:0015031,endoplasmic reticulum lumen; protein transport,,,,,,,,,,SIL1_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp127993_c0_seq1,855,41.4035,0.64019858,1667,7143,,1.00E-13,Q4R6U7,"39S ribosomal protein L30, mitochondrial (L30mt) (MRP-L30)","39S ribosomal protein L30, mitochondrial (L30mt) (MRP-L30)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF00327;,,,,,,,,,RM30_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp127997_c0_seq1,1282,41.6537,0.93807706,4955,21,male>female,1.00E-07,Q6AXY2,Uncharacterized protein C6orf201 homolog,Uncharacterized protein C6orf201 homolog,,,PF15023;,,,,,,,,,CF201_RAT,Rattus norvegicus (Rat), comp128001_c0_seq1,2035,41.6708,0.46850317,329,305,,0,Q9R1K5,Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog),Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog),GO:0006281; GO:0031572; GO:0051488; GO:0005680; GO:0031145; GO:0051301; GO:0070306; GO:0007067; GO:0090344; GO:0031965; GO:0008284; GO:0045732; GO:0016567; GO:0040020,DNA repair; G2 DNA damage checkpoint; activation of anaphase-promoting complex activity; anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; lens fiber cell differentiation; mitosis; negative regulation of cell aging; nuclear membrane; positive regulation of cell proliferation; positive regulation of protein catabolic process; protein ubiquitination; regulation of meiosis,PF12894;PF00400;,0,CHOYP_FZR.1.1,,,,,,,FZR_MOUSE,Mus musculus (Mouse),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; DNA repair [GO:0006281]; G2 DNA damage checkpoint [GO:0031572]; lens fiber cell differentiation [GO:0070306]; mitotic nuclear division [GO:0007067]; negative regulation of cell aging [GO:0090344]; positive regulation of cell proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of meiotic nuclear division [GO:0040020] comp128004_c1_seq1,710,43.662,0.24076238,21,11,,9.00E-95,Q9QZD8,Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10),Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10),GO:0016021; GO:0005743; GO:0006839; GO:0015291,integral to membrane; mitochondrial inner membrane; mitochondrial transport; secondary active transmembrane transporter activity,PF00153;,1.00E-57,CHOYP_K11G12.5.1.1,,,,,,,DIC_MOUSE,Mus musculus (Mouse),mitochondrial transport [GO:0006839]; thiosulfate transport [GO:0015709]; translation [GO:0006412] comp128009_c0_seq1,961,44.8491,0.33255589,8,169,,2.00E-63,B1AK53,Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein),Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein),GO:0017124; GO:0051015; GO:0005903; GO:0005737; GO:0031941; GO:0007626; GO:0051494; GO:0030046; GO:0051491; GO:0007605; GO:0032420; GO:0032426,SH3 domain binding; actin filament binding; brush border; cytoplasm; filamentous actin; locomotory behavior; negative regulation of cytoskeleton organization; parallel actin filament bundle assembly; positive regulation of filopodium assembly; sensory perception of sound; stereocilium; stereocilium bundle tip,PF12796;PF02205;,,,,,,,,,ESPN_HUMAN,Homo sapiens (Human),locomotory behavior [GO:0007626]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605] comp128015_c0_seq1,654,49.5413,0.3801665,37,60,,6.00E-58,O34660,Putative aldehyde dehydrogenase DhaS (EC 1.2.1.3),Putative aldehyde dehydrogenase DhaS (EC 1.2.1.3),GO:0004029,aldehyde dehydrogenase (NAD) activity,PF00171;,1.00E-63,CHOYP_BRAFLDRAFT_287353.1.1,,,,,,,ALDH4_BACSU,Bacillus subtilis (strain 168),cellular aldehyde metabolic process [GO:0006081] comp128025_c0_seq1,602,44.0199,0.27543755,44,19,,,,,,,,,7.00E-35,CHOYP_LOC100375699.2.2,,,,,,,,, comp128025_c1_seq1,1159,42.1915,0.41393404,95,86,,2.00E-52,Q9QY53,Nephrocystin-1,Nephrocystin-1,GO:0005912; GO:0030030; GO:0005911; GO:0034613; GO:0035085; GO:0005856; GO:0031514; GO:0035845; GO:0032391; GO:0060041; GO:0048515; GO:0005923,adherens junction; cell projection organization; cell-cell junction; cellular protein localization; cilium axoneme; cytoskeleton; motile cilium; photoreceptor cell outer segment organization; photoreceptor connecting cilium; retina development in camera-type eye; spermatid differentiation; tight junction,PF00018;,,,,,,,,,NPHP1_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; cellular protein localization [GO:0034613]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; spermatid differentiation [GO:0048515] comp128030_c0_seq2,1001,34.7652,0.62914802,711,214,,4.00E-13,Q8TD35,Uncharacterized protein C20orf201,Protein LKAAEAR1 (LKAAEAR motif-containing protein 1),,,PF15478;,1.00E-53,CHOYP_LOC100369389.1.1,,,,,,,CT201_HUMAN,Homo sapiens (Human), comp128031_c0_seq1,1042,47.1209,0.64524872,90,45,,7.00E-06,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp128033_c0_seq3,1186,42.8331,0.57292145,20,115,,2.00E-138,Q08CI4,Cyclin-Y-like protein 1,Cyclin-Y-like protein 1,GO:0000079,regulation of cyclin-dependent protein serine/threonine kinase activity,PF00134;,7.00E-108,CHOYP_LOC100864008.1.1,,,,,,,CCYL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] comp128034_c0_seq1,870,47.3563,0.71739436,79,88,,2.00E-111,P11497,Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)],Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)],GO:0005524; GO:0003989; GO:0006084; GO:0009374; GO:0004075; GO:0005829; GO:0006633; GO:2001295; GO:0046872; GO:0051289; GO:0042493; GO:0014070,ATP binding; acetyl-CoA carboxylase activity; acetyl-CoA metabolic process; biotin binding; biotin carboxylase activity; cytosol; fatty acid biosynthetic process; malonyl-CoA biosynthetic process; metal ion binding; protein homotetramerization; response to drug; response to organic cyclic compound,PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;,,,,,,,,,ACACA_RAT,Rattus norvegicus (Rat),acetyl-CoA metabolic process [GO:0006084]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; protein homotetramerization [GO:0051289]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070] comp128034_c1_seq1,549,50.6375,0.31445011,36,21,,1.00E-69,P78820,Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Cell untimely torn protein 6) [Includes: Biotin carboxylase (EC 6.3.4.14)],Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Cell untimely torn protein 6) [Includes: Biotin carboxylase (EC 6.3.4.14)],GO:0005524; GO:0003989; GO:0004075; GO:0005829; GO:0000329; GO:0042759; GO:2001295; GO:0046872; GO:0007088,ATP binding; acetyl-CoA carboxylase activity; biotin carboxylase activity; cytosol; fungal-type vacuole membrane; long-chain fatty acid biosynthetic process; malonyl-CoA biosynthetic process; metal ion binding; regulation of mitosis,PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;,1.00E-76,CHOYP_ACAC.1.2,,,,,,,ACAC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295] comp128038_c1_seq1,442,45.0226,0.2238742,17,53,,3.00E-73,P07992,DNA excision repair protein ERCC-1,DNA excision repair protein ERCC-1,GO:0009650; GO:0008283; GO:0051276; GO:0005737; GO:0003684; GO:0006302; GO:0048568; GO:0004519; GO:0007281; GO:0045190; GO:0008584; GO:0006312; GO:0035264; GO:0010259; GO:0043066; GO:0032205; GO:0000784; GO:0005654; GO:0000109; GO:0000718; GO:0006295; GO:0006296; GO:0048477; GO:0035166; GO:0000720; GO:0001302; GO:0010165; GO:0007584; GO:0006979; GO:0009744; GO:0003697; GO:0007283; GO:0006949; GO:0005669; GO:0006283,"UV protection; cell proliferation; chromosome organization; cytoplasm; damaged DNA binding; double-strand break repair; embryonic organ development; endonuclease activity; germ cell development; isotype switching; male gonad development; mitotic recombination; multicellular organism growth; multicellular organismal aging; negative regulation of apoptotic process; negative regulation of telomere maintenance; nuclear chromosome, telomeric region; nucleoplasm; nucleotide-excision repair complex; nucleotide-excision repair, DNA damage removal; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; oogenesis; post-embryonic hemopoiesis; pyrimidine dimer repair by nucleotide-excision repair; replicative cell aging; response to X-ray; response to nutrient; response to oxidative stress; response to sucrose stimulus; single-stranded DNA binding; spermatogenesis; syncytium formation; transcription factor TFIID complex; transcription-coupled nucleotide-excision repair",,4.00E-36,CHOYP_ERCC1.1.1,,,,,,,ERCC1_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative cell aging [GO:0001302]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]" comp128039_c0_seq1,1296,38.6574,0.88980237,195,755,,3.00E-92,Q10751,Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),GO:0004180; GO:0016021; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,3.00E-24,CHOYP_LRP6.3.6,,,,,,,ACE_CHICK,Gallus gallus (Chicken), comp128047_c0_seq1,1497,33.5337,0.80953119,355,3123,,2.00E-56,Q5RAT5,Protein LSM12 homolog,Protein LSM12 homolog,,,PF09793;,7.00E-33,CHOYP_LSM12.1.1,,,,,,,LSM12_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp128055_c0_seq1,1149,28.7206,0.88822753,71,458,,,,,,,,,,,2.00E-42,ruditapes_c9464,,,,,,, comp128056_c0_seq1,227,44.0529,0.276369,3,8,,4.00E-07,O96612,Ubiquitin hydrolase B (EC 3.4.19.12),Ubiquitin hydrolase B (EC 3.4.19.12),GO:0008234; GO:0016579; GO:0004221; GO:0006511,cysteine-type peptidase activity; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBPB_DICDI,Dictyostelium discoideum (Slime mold),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128056_c1_seq1,1118,44.186,0.4771624,78,46,,9.00E-95,Q0V9G5,Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44),Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44),GO:0051322; GO:0051301; GO:0007067; GO:0060564; GO:0005634; GO:0016579; GO:0090231; GO:0004221; GO:0006511; GO:0004843; GO:0008270,anaphase; cell division; mitosis; negative regulation of mitotic anaphase-promoting complex activity; nucleus; protein deubiquitination; regulation of spindle checkpoint; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding,PF00443;PF02148;,5.00E-46,CHOYP_LOC100375318.1.1,,,,,,,UBP44_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; protein deubiquitination [GO:0016579]; regulation of spindle checkpoint [GO:0090231]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128061_c0_seq2,1178,36.0781,0.50029069,457,1123,,3.00E-49,Q9VCC3,"28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt)","28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt)",GO:0005762; GO:0005763; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; mitochondrial small ribosomal subunit; structural constituent of ribosome; translation,PF14955;,,,9.00E-16,ruditapes2_c958,,,,,RT24_DROME,Drosophila melanogaster (Fruit fly),mitochondrial translation [GO:0032543]; translation [GO:0006412] comp128062_c0_seq4,2305,42.9501,0.46517017,71,467,,2.00E-11,Q3U3I9,Zinc finger protein 865,Zinc finger protein 865,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN865_MOUSE,Mus musculus (Mouse),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp128074_c1_seq1,1178,42.1053,0.53958849,69,655,,2.00E-90,Q3TJZ6,Protein FAM98A,Protein FAM98A,,,PF10239;,1.00E-61,CHOYP_LOC100372505.1.2,1.00E-19,ruditapes_c3563,,,,,FA98A_MOUSE,Mus musculus (Mouse), comp128077_c0_seq1,952,41.8067,0.64686144,84,149,,2.00E-64,P14207,"Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP)","Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP)",GO:0031225; GO:0005576; GO:0005542; GO:0015884; GO:0016020; GO:0005886,anchored to membrane; extracellular region; folic acid binding; folic acid transport; membrane; plasma membrane,PF03024;,,,,,,,,,FOLR2_HUMAN,Homo sapiens (Human),folic acid transport [GO:0015884]; inflammatory response [GO:0006954]; positive regulation of cell proliferation [GO:0008284]; receptor-mediated endocytosis [GO:0006898]; regulation of thymidylate synthase biosynthetic process [GO:0050758] comp128080_c0_seq1,1311,41.9527,0.47960386,56,120,,8.00E-60,Q08DA3,Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),GO:0051301; GO:0004197; GO:0042393; GO:0016578; GO:0007067; GO:0005634; GO:0045893; GO:0051289; GO:0003713; GO:0006351; GO:0043130; GO:0004221; GO:0006511; GO:0004843; GO:0008270,"cell division; cysteine-type endopeptidase activity; histone binding; histone deubiquitination; mitosis; nucleus; positive regulation of transcription, DNA-dependent; protein homotetramerization; transcription coactivator activity; transcription, DNA-dependent; ubiquitin binding; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding",PF00443;PF02148;,3.00E-36,CHOYP_LOC585494.1.1,,,,,,,UBP16_BOVIN,Bos taurus (Bovine),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; histone deubiquitination [GO:0016578]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translational elongation [GO:0045901]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp128085_c0_seq1,1023,40.6647,0.27035356,10,142,,6.00E-106,Q62651,"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)","Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)",GO:0006635; GO:0016853; GO:0046872; GO:0005739; GO:0005777,fatty acid beta-oxidation; isomerase activity; metal ion binding; mitochondrion; peroxisome,PF00378;,1.00E-58,CHOYP_ECH1.1.1,,,,,,,ECH1_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062] comp128085_c0_seq2,1032,40.8915,0.26524301,0,0,,5.00E-63,Q54SS0,"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)","Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)",GO:0051750; GO:0006635; GO:0005739; GO:0005777,"delta3,5-delta2,4-dienoyl-CoA isomerase activity; fatty acid beta-oxidation; mitochondrion; peroxisome",PF00378;,,,9.00E-110,ruditapes2_c2308,,,,,ECH1_DICDI,Dictyostelium discoideum (Slime mold),fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062] comp128085_c0_seq3,1132,40.5477,0.33412656,69,240,,6.00E-109,Q62651,"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)","Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)",GO:0006635; GO:0016853; GO:0046872; GO:0005739; GO:0005777,fatty acid beta-oxidation; isomerase activity; metal ion binding; mitochondrion; peroxisome,PF00378;,,,,,,,,,ECH1_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062] comp128085_c0_seq4,978,41.002,0.28242883,0,6,,2.00E-30,Q7U004,Probable enoyl-CoA hydratase echA12 (EC 4.2.1.17),Probable enoyl-CoA hydratase echA12 (EC 4.2.1.17),GO:0004300; GO:0006631,enoyl-CoA hydratase activity; fatty acid metabolic process,PF00378;,,,,,,,,,ECH12_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),fatty acid metabolic process [GO:0006631] comp128085_c0_seq5,987,41.54,0.26831945,12,130,,6.00E-31,P52046,3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) (Crotonase),Short-chain-enoyl-CoA hydratase (EC 4.2.1.150) (3-hydroxybutyryl-CoA dehydratase) (Crotonase),GO:0003859; GO:0019605,3-hydroxybutyryl-CoA dehydratase activity; butyrate metabolic process,PF00378;,,,,,,,,,CRT_CLOAB,Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787),butyrate metabolic process [GO:0019605] comp128089_c0_seq1,595,40.5042,0.58562771,0,1,,8.00E-79,P27639,Eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Initiation factor 1),Eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Initiation factor 1),GO:0005524; GO:0008026; GO:0003743,ATP binding; ATP-dependent helicase activity; translation initiation factor activity,PF00270;PF00271;,4.00E-63,CHOYP_EIF4A1.1.1,1.00E-73,ruditapes_c8263,,,,,IF4A_CAEEL,Caenorhabditis elegans,regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; translational initiation [GO:0006413] comp128089_c0_seq2,637,40.6593,0.53937331,0,0,,6.00E-49,Q4E162,Probable eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A),Probable eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A),GO:0005524; GO:0008026; GO:0003743,ATP binding; ATP-dependent helicase activity; translation initiation factor activity,PF00270;PF00271;,,,2.00E-33,ruditapes_c209,,,,,IF4A_TRYCC,Trypanosoma cruzi (strain CL Brener), comp128094_c0_seq1,1216,35.9375,0.54667417,246,7,,,,,,,,,5.00E-21,CHOYP_LOC793702.1.1,,,,,,,,, comp128095_c0_seq1,2641,30.178,0.61592075,6938,3541,,4.00E-129,Q8BTU1,UPF0468 protein C16orf80 homolog (Gene trap locus 3 protein),Cilia- and flagella-associated protein 20 (Gene trap locus 3 protein),GO:0005929,cilium,PF05018;,0,CHOYP_CP080.1.1,2.00E-41,ruditapes_c22931,,,,,CP080_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; positive regulation of cell motility [GO:2000147]; positive regulation of feeding behavior [GO:2000253]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296] comp128099_c0_seq1,1737,41.2781,0.31314835,55,215,,9.00E-97,Q6P6B7,Ankyrin repeat domain-containing protein 16,Ankyrin repeat domain-containing protein 16,,,PF00023;PF12796;,,,,,,,,,ANR16_HUMAN,Homo sapiens (Human), comp128105_c1_seq1,505,45.3465,0.31249158,24,60,,2.00E-61,Q9D5V5,Cullin-5 (CUL-5),Cullin-5 (CUL-5),GO:0031466; GO:0005737; GO:0051480; GO:0005634; GO:0005886; GO:0016567; GO:0006970; GO:0006511,Cul5-RING ubiquitin ligase complex; cytoplasm; cytosolic calcium ion homeostasis; nucleus; plasma membrane; protein ubiquitination; response to osmotic stress; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,9.00E-102,CHOYP_LOC100371275.1.1,,,,,,,CUL5_MOUSE,Mus musculus (Mouse),cerebral cortex radially oriented cell migration [GO:0021799]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; radial glia guided migration of Purkinje cell [GO:0021942] comp128111_c0_seq2,765,42.6144,0.38052723,29,5,,5.00E-54,Q920Q2,DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase),DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase),GO:0006260; GO:0003887; GO:0003684; GO:0017125; GO:0042276; GO:0000287; GO:0005634; GO:0009411,DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; deoxycytidyl transferase activity; error-prone translesion synthesis; magnesium ion binding; nucleus; response to UV,PF16589;PF14377;PF00817;PF11799;PF16727;,6.00E-37,CHOYP_BRAFLDRAFT_213587.1.1,,,,,,,REV1_MOUSE,Mus musculus (Mouse),error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411] comp128111_c1_seq1,216,48.6111,0.31842209,6,0,,3.00E-11,A3QGY9,DNA polymerase IV (Pol IV) (EC 2.7.7.7),DNA polymerase IV (Pol IV) (EC 2.7.7.7),GO:0006281; GO:0006261; GO:0003887; GO:0005737; GO:0003684; GO:0000287,DNA repair; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; cytoplasm; damaged DNA binding; magnesium ion binding,PF00817;PF11799;PF11798;,,,,,,,,,DPO4_SHELP,Shewanella loihica (strain ATCC BAA-1088 / PV-4),DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281] comp128113_c0_seq2,1087,38.7305,0.24980505,5,0,,2.00E-24,Q86YA3,Uncharacterized protein C4orf21,Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1),GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF10382;PF06839;,,,,,,,,,CD021_HUMAN,Homo sapiens (Human), comp128113_c0_seq4,343,42.2741,0.14110046,0,0,,2.00E-06,O74939,Uncharacterized protein C553.01c,Uncharacterized protein C553.01c,GO:0045132; GO:0044732; GO:0005634; GO:0035861,meiotic chromosome segregation; mitotic spindle pole body; nucleus; site of double-strand break,PF10382;,,,,,,,,,YJB1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp128127_c0_seq2,1302,39.7081,0.41452835,0,0,,1.00E-109,Q9U1M2,Transmembrane protein 120 homolog,Transmembrane protein 120 homolog,GO:0050829; GO:0016021; GO:0045089,defense response to Gram-negative bacterium; integral to membrane; positive regulation of innate immune response,PF07851;,7.00E-58,CHOYP_PHUM_PHUM320270.1.1,,,,,,,TM120_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; positive regulation of innate immune response [GO:0045089] comp128130_c0_seq1,2029,31.5919,0.29664492,991,2881,,,,,,,,,,,2.00E-33,ruditapes_c9559,,,,,,, comp128133_c1_seq1,682,39.1496,0.56815333,42,59,,4.00E-103,P55745,Ras-related protein Rab-21,Ras-related protein Rab-21,GO:0019003; GO:0005525; GO:0003924; GO:0000139; GO:0030659; GO:0031901; GO:0005789; GO:0015031; GO:0007264,GDP binding; GTP binding; GTPase activity; Golgi membrane; cytoplasmic vesicle membrane; early endosome membrane; endoplasmic reticulum membrane; protein transport; small GTPase mediated signal transduction,PF00071;,2.00E-117,CHOYP_RAB21.1.1,,,,,,,RAB21_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264] comp128135_c0_seq2,862,38.051,0.83624144,0,4,,4.00E-14,A1L1W9,Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,MOT10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ion transmembrane transport [GO:0034220] comp128136_c0_seq1,312,37.8205,1.16056068,34,11,,,,,,,,,,,7.00E-23,ruditapes_c7042,,,,,,, comp128136_c0_seq2,324,37.6543,1.58538096,34,6,,7.00E-12,P91889,FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,9.00E-11,CHOYP_FMRF.3.4,,,,,,,FMRF_SEPOF,Sepia officinalis (Common cuttlefish),neuropeptide signaling pathway [GO:0007218] comp128138_c0_seq2,659,39.302,0.94691753,49,213,,8.00E-12,P50461,"Cysteine and glycine-rich protein 3 (Cardiac LIM protein) (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein)","Cysteine and glycine-rich protein 3 (Cardiac LIM protein) (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein)",GO:0030018; GO:0042805; GO:0060048; GO:0003300; GO:0055003; GO:0006874; GO:0005856; GO:0035995; GO:0005634; GO:0033365; GO:0002026; GO:0007519; GO:0008307; GO:0031433; GO:0008270,Z disc; actinin binding; cardiac muscle contraction; cardiac muscle hypertrophy; cardiac myofibril assembly; cellular calcium ion homeostasis; cytoskeleton; detection of muscle stretch; nucleus; protein localization to organelle; regulation of the force of heart contraction; skeletal muscle tissue development; structural constituent of muscle; telethonin binding; zinc ion binding,PF00412;,4.00E-26,CHOYP_SMP_079270.4.4,2.00E-39,ruditapes2_c446,,,,,CSRP3_HUMAN,Homo sapiens (Human),blood vessel remodeling [GO:0001974]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue development [GO:0048738]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; negative regulation of actin filament severing [GO:1903919]; negative regulation of myoblast differentiation [GO:0045662]; positive regulation of actin filament severing [GO:1903920]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization to organelle [GO:0033365]; regulation of the force of heart contraction [GO:0002026]; skeletal muscle tissue development [GO:0007519] comp128153_c0_seq1,1071,38.5621,0.48129345,229,80,,1.00E-16,P0CW27,Coiled-coil domain-containing protein 166,Coiled-coil domain-containing protein 166,,,PF14988;,4.00E-78,CHOYP_LOC100374036.1.1,,,,,,,CC166_HUMAN,Homo sapiens (Human), comp128155_c0_seq1,250,45.2,1.23041184,1,5,,,,,,,,,3.00E-28,CHOYP_LOC579418.1.2,,,,,,,,, comp128155_c1_seq1,448,46.2054,0.80058582,1,40,,5.00E-37,A2AJN7,Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11),Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11),GO:0042044; GO:0005452; GO:0016021; GO:0050801; GO:0005886; GO:0046983; GO:0015293,fluid transport; inorganic anion exchanger activity; integral to membrane; ion homeostasis; plasma membrane; protein dimerization activity; symporter activity,PF00955;,2.00E-59,CHOYP_ISCW_ISCW009278.1.1,,,,,,,S4A11_MOUSE,Mus musculus (Mouse),bicarbonate transport [GO:0015701]; borate transmembrane transport [GO:0035445]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; fluid transport [GO:0042044]; ion homeostasis [GO:0050801]; proton transport [GO:0015992]; regulation of intracellular pH [GO:0051453]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] comp128157_c0_seq2,1191,43.6608,0.29084275,0,0,,1.00E-101,Q8R3S6,Exocyst complex component 1 (Exocyst complex component Sec3),Exocyst complex component 1 (Exocyst complex component Sec3),GO:0006887; GO:0005886; GO:0015031,exocytosis; plasma membrane; protein transport,PF15277;PF09763;,,,,,,,,,EXOC1_MOUSE,Mus musculus (Mouse),exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane organization [GO:0061024]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031] comp128157_c0_seq3,1796,45.6013,0.33712792,31,37,,4.00E-145,Q8R3S6,Exocyst complex component 1 (Exocyst complex component Sec3),Exocyst complex component 1 (Exocyst complex component Sec3),GO:0006887; GO:0005886; GO:0015031,exocytosis; plasma membrane; protein transport,PF15277;PF09763;,4.00E-113,CHOYP_EXOC1.1.2,,,,,,,EXOC1_MOUSE,Mus musculus (Mouse),exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane organization [GO:0061024]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031] comp128157_c0_seq6,1088,41.4522,0.27926405,0,14,,6.00E-63,Q20678,Exocyst complex component 1 (Exocyst complex component Sec3),Exocyst complex component 1 (Exocyst complex component Sec3),GO:0006887; GO:0015031,exocytosis; protein transport,PF15277;PF09763;,,,,,,,,,EXOC1_CAEEL,Caenorhabditis elegans,exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] comp128157_c0_seq7,943,41.7815,0.3183154,0,0,,4.00E-13,Q54NV1,Exocyst complex component 1 (Exocyst complex component Sec3),Exocyst complex component 1 (Exocyst complex component Sec3),GO:0006887; GO:0015031,exocytosis; protein transport,PF09763;,1.00E-97,CHOYP_EXOC1.2.2,,,,,,,EXOC1_DICDI,Dictyostelium discoideum (Slime mold),exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] comp128158_c0_seq1,1118,40.3399,0.33311529,110,1179,,7.00E-69,B8JMH0,"Putative transferase CAF17 homolog, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)","Putative transferase CAF17 homolog, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)",GO:0004047; GO:0006546; GO:0006783; GO:0005739,aminomethyltransferase activity; glycine catabolic process; heme biosynthetic process; mitochondrion,PF01571;PF08669;,,,4.00E-32,ruditapes_c27363,,,,,CAF17_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),heme biosynthetic process [GO:0006783]; iron-sulfur cluster assembly [GO:0016226] comp128159_c3_seq1,487,41.4784,1.06087404,3,79,,5.00E-31,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp128164_c0_seq1,366,58.4699,1.11481222,6,24,,4.00E-44,P01744,Ig heavy chain V-I region ND (Fragments),,GO:0038095; GO:0038096; GO:0003823; GO:0006958; GO:0005576; GO:0045087; GO:0005886,"Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; antigen binding; complement activation, classical pathway; extracellular region; innate immune response; plasma membrane",,,,,,,,,,HV104_HUMAN,, comp128164_c0_seq2,357,59.1036,1.09147198,0,24,,3.00E-57,P01742,Ig heavy chain V-I region EU,Ig heavy chain V-I region EU,GO:0038095; GO:0038096; GO:0003823; GO:0006958; GO:0005576; GO:0045087; GO:0005886,"Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; antigen binding; complement activation, classical pathway; extracellular region; innate immune response; plasma membrane",PF07686;,,,,,,,,,HV101_HUMAN,Homo sapiens (Human),"complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; receptor-mediated endocytosis [GO:0006898]; regulation of immune response [GO:0050776]" comp128176_c0_seq1,1088,40.9007,0.57619096,71,434,,6.00E-106,O75792,Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A),Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A),GO:0006260; GO:0003723; GO:0006401; GO:0046872; GO:0005634; GO:0004523; GO:0032299,DNA replication; RNA binding; RNA catabolic process; metal ion binding; nucleus; ribonuclease H activity; ribonuclease H2 complex,PF01351;,2.00E-69,CHOYP_BRAFLDRAFT_285333.1.1,1.00E-82,ruditapes_c24995,,,,,RNH2A_HUMAN,Homo sapiens (Human),"DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]; RNA catabolic process [GO:0006401]" comp128176_c0_seq2,781,39.1805,0.55586745,0,12,,3.00E-06,Q8TYV5,Ribonuclease HII (RNase HII) (EC 3.1.26.4),Ribonuclease HII (RNase HII) (EC 3.1.26.4),GO:0003723; GO:0006401; GO:0005737; GO:0030145; GO:0090305; GO:0004523,RNA binding; RNA catabolic process; cytoplasm; manganese ion binding; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity,PF01351;,,,5.00E-23,ruditapes2_c2376,,,,,RNH2_METKA,Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938),RNA catabolic process [GO:0006401] comp128180_c2_seq1,770,41.9481,0.97633722,8,137,,1.00E-134,O95835,Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts),Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts),GO:0005524; GO:0000086; GO:0051301; GO:0051220; GO:0005829; GO:0035329; GO:0009755; GO:0030216; GO:0000287; GO:0005815; GO:0007067; GO:0090090; GO:0045736; GO:0033138; GO:0004674; GO:0030833; GO:0000819; GO:0000922,ATP binding; G2/M transition of mitotic cell cycle; cell division; cytoplasmic sequestering of protein; cytosol; hippo signaling cascade; hormone-mediated signaling pathway; keratinocyte differentiation; magnesium ion binding; microtubule organizing center; mitosis; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cyclin-dependent protein serine/threonine kinase activity; positive regulation of peptidyl-serine phosphorylation; protein serine/threonine kinase activity; regulation of actin filament polymerization; sister chromatid segregation; spindle pole,PF00069;PF00627;,7.00E-150,CHOYP_LATS2.1.1,,,,,,,LATS1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; hippo signaling [GO:0035329]; hormone-mediated signaling pathway [GO:0009755]; inner cell mass cell fate commitment [GO:0001827]; inner cell mass cellular morphogenesis [GO:0001828]; keratinocyte differentiation [GO:0030216]; mitotic nuclear division [GO:0007067]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; positive regulation of apoptotic process [GO:0043065]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of organ growth [GO:0046620]; regulation of protein complex assembly [GO:0043254]; sister chromatid segregation [GO:0000819] comp128182_c0_seq1,1122,36.3636,0.29689739,143,719,,8.00E-37,Q5XK67,DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D),DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D),GO:0003677; GO:0003899; GO:0005634; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; nucleus; transcription, DNA-dependent",,,,,,,,,,RPAC2_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp128185_c0_seq2,874,45.6522,0.78029556,34,90,,,,,,,,,2.00E-11,CHOYP_LOC100888608.1.3,2.00E-28,ruditapes2_c630,,,,,,, comp128189_c0_seq2,1168,42.2089,0.4732797,52,28,,3.00E-29,P84104,"Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3)","Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3)",GO:0003723; GO:0008380; GO:0008286; GO:0006397; GO:0016607; GO:0000166,RNA binding; RNA splicing; insulin receptor signaling pathway; mRNA processing; nuclear speck; nucleotide binding,PF00076;,2.00E-32,CHOYP_RBP1.2.2,,,,,,,SRSF3_MOUSE,Mus musculus (Mouse),"insulin receptor signaling pathway [GO:0008286]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]" comp128190_c2_seq1,291,40.5498,0.7729503,2,16,,3.00E-23,Q5RBL0,Protein YIPF1 (YIP1 family member 1),Protein YIPF1 (YIP1 family member 1),GO:0016021,integral to membrane,PF04893;,5.00E-26,CHOYP_BRAFLDRAFT_70406.1.1,,,,,,,YIPF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp128195_c0_seq1,780,38.7179,0.75475635,142,1842,,3.00E-23,Q9NUS5,AP-5 complex subunit sigma-1 (Adapter-related protein complex 5 sigma subunit) (Sigma5),AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5),GO:0030119; GO:0005829; GO:0000724; GO:0016197; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0015031,AP-type membrane coat adaptor complex; cytosol; double-strand break repair via homologous recombination; endosomal transport; late endosome; late endosome membrane; lysosomal membrane; lysosome; protein transport,PF15001;,7.00E-11,CHOYP_LOC100367116.1.1,,,,,,,AP5S1_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031] comp128196_c0_seq1,888,34.009,0.71848151,13,302,,2.00E-32,Q9CQR7,Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2),Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2),GO:0005794; GO:0007220; GO:0007219; GO:0005783; GO:0005789; GO:0005887; GO:0006509; GO:0043085; GO:0016485,Golgi apparatus; Notch receptor processing; Notch signaling pathway; endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; membrane protein ectodomain proteolysis; positive regulation of catalytic activity; protein processing,PF10251;,8.00E-30,CHOYP_LOC584085.1.1,6.00E-42,ruditapes2_c609,,,,,PEN2_MOUSE,Mus musculus (Mouse),membrane protein ectodomain proteolysis [GO:0006509]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485] comp128197_c0_seq1,1978,39.8382,0.35182926,49,2,,3.00E-121,Q6PZ02,Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B),Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B),GO:0006914; GO:0008234; GO:0005737; GO:0015031; GO:0006508,autophagy; cysteine-type peptidase activity; cytoplasm; protein transport; proteolysis,PF03416;,6.00E-61,CHOYP_PP1B.1.3,,,,,,,ATG4B_CHICK,Gallus gallus (Chicken),autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein delipidation [GO:0051697]; protein processing [GO:0016485]; protein targeting to membrane [GO:0006612] comp128197_c0_seq2,1594,39.4605,0.34435091,0,0,,1.00E-62,Q6PZ02,Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B),Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B),GO:0006914; GO:0008234; GO:0005737; GO:0015031; GO:0006508,autophagy; cysteine-type peptidase activity; cytoplasm; protein transport; proteolysis,PF03416;,,,6.00E-26,ruditapes_c20395,,,,,ATG4B_CHICK,Gallus gallus (Chicken),autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein delipidation [GO:0051697]; protein processing [GO:0016485]; protein targeting to membrane [GO:0006612] comp128209_c0_seq1,1103,44.515,0.44746212,1019,5822,,9.00E-90,O54873,Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)],Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)],GO:0005794; GO:0001525; GO:0006915; GO:0007155; GO:0005829; GO:0005783; GO:0005615; GO:0006006; GO:0006954; GO:0005634; GO:0000049; GO:0006412; GO:0030133,Golgi apparatus; angiogenesis; apoptotic process; cell adhesion; cytosol; endoplasmic reticulum; extracellular space; glucose metabolic process; inflammatory response; nucleus; tRNA binding; translation; transport vesicle,PF01588;,2.00E-25,CHOYP_AIMP1.1.1,,,,,,,AIMP1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; glucose metabolic process [GO:0006006]; inflammatory response [GO:0006954]; translation [GO:0006412] comp128213_c0_seq1,1237,42.6031,0.44751331,64,75,,2.00E-65,Q99698,Lysosomal-trafficking regulator (Beige homolog),Lysosomal-trafficking regulator (Beige homolog),GO:0002456; GO:0007596; GO:0005829; GO:0042742; GO:0042832; GO:0051607; GO:0032510; GO:0030595; GO:0007040; GO:0033364; GO:0032438; GO:0015630; GO:0007017; GO:0042267; GO:0002446; GO:0055091; GO:0006644; GO:0032816; GO:0042493; GO:0033299,T cell mediated immunity; blood coagulation; cytosol; defense response to bacterium; defense response to protozoan; defense response to virus; endosome to lysosome transport via multivesicular body sorting pathway; leukocyte chemotaxis; lysosome organization; mast cell secretory granule organization; melanosome organization; microtubule cytoskeleton; microtubule-based process; natural killer cell mediated cytotoxicity; neutrophil mediated immunity; phospholipid homeostasis; phospholipid metabolic process; positive regulation of natural killer cell activation; response to drug; secretion of lysosomal enzymes,PF02138;PF14844;PF00400;,2.00E-20,CHOYP_BRAFLDRAFT_126843.1.1,,,,,,,LYST_HUMAN,Homo sapiens (Human),defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031] comp128225_c0_seq1,1572,41.1578,0.58812218,80,104,,2.00E-26,Q5XH29,Centromere protein N-A (CENP-N-A),Centromere protein N-A (CENP-N-A),GO:0034508; GO:0007059; GO:0000775; GO:0007067; GO:0005634,"centromere complex assembly; chromosome segregation; chromosome, centromeric region; mitosis; nucleus",PF05238;,,,,,,,,,CENNA_XENLA,Xenopus laevis (African clawed frog),centromere complex assembly [GO:0034508]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067] comp128227_c0_seq1,1352,35.5769,1.17992879,498,2907,,2.00E-12,Q5E9A5,Growth arrest and DNA damage-inducible protein GADD45 beta,Growth arrest and DNA damage-inducible protein GADD45 beta,GO:0000186; GO:0006915; GO:0030154; GO:0007275; GO:0006469; GO:0005634; GO:0051726; GO:0006950,activation of MAPKK activity; apoptotic process; cell differentiation; multicellular organismal development; negative regulation of protein kinase activity; nucleus; regulation of cell cycle; response to stress,PF01248;,,,2.00E-18,ruditapes2_c424,,,,,GA45B_BOVIN,Bos taurus (Bovine),activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950] comp128238_c0_seq1,809,38.0717,1.19787228,13,97,,4.00E-25,Q91XA9,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (YNL),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (YNL),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,,,,,,,,,CHIA_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp128238_c1_seq1,305,42.9508,0.57143471,4,32,,6.00E-09,Q2PQM7,Chitinase-like protein Idgf4 (Imaginal disk growth factor protein 4),Chitinase-like protein Idgf4 (Imaginal disk growth factor protein 4),GO:0005975; GO:0006032; GO:0004568; GO:0005576; GO:0007275,carbohydrate metabolic process; chitin catabolic process; chitinase activity; extracellular region; multicellular organismal development,PF00704;,,,,,,,,,IDGF4_GLOMM,Glossina morsitans morsitans (Savannah tsetse fly),carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; multicellular organism development [GO:0007275] comp128239_c0_seq2,1810,39.8343,1.03243383,21,235,,,,,,,,,,,2.00E-25,ruditapes_c10969,,,,,,, comp128240_c0_seq3,474,45.1477,1.08021123,0,0,,,,,,,,,,,2.00E-13,ruditapes_c10755,,,,,,, comp128241_c0_seq2,683,45.9736,0.91505213,0,3,,7.00E-15,Q19673,Putative tyrosinase-like protein tyr-3,Putative tyrosinase-like protein tyr-3,GO:0046872; GO:0004497,metal ion binding; monooxygenase activity,PF01549;PF00264;,,,,,,,,,TYR3_CAEEL,Caenorhabditis elegans, comp128245_c0_seq1,3907,38.8789,0.44714427,374,345,,,,,,,,,2.00E-50,CHOYP_DMOJ_GI15291.1.1,,,,,,,,, comp128246_c0_seq1,384,39.0625,1.09589784,7,8,,1.00E-06,Q91W36,Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3),Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3),GO:0006281; GO:0008234; GO:0016578; GO:0000278; GO:0000790; GO:0031647; GO:0004221; GO:0006511; GO:0008270,DNA repair; cysteine-type peptidase activity; histone deubiquitination; mitotic cell cycle; nuclear chromatin; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF00443;PF02148;,,,,,,,,,UBP3_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128246_c1_seq1,687,42.5036,0.42244563,30,45,,3.00E-19,A8HAL1,Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),GO:0051301; GO:0004197; GO:0070537; GO:0042393; GO:0007067; GO:0005634; GO:0045893; GO:0045901; GO:0051289; GO:0006974; GO:0003713; GO:0006351; GO:0043130; GO:0004221; GO:0006511; GO:0004843; GO:0008270,"cell division; cysteine-type endopeptidase activity; histone H2A K63-linked deubiquitination; histone binding; mitosis; nucleus; positive regulation of transcription, DNA-dependent; positive regulation of translational elongation; protein homotetramerization; response to DNA damage stimulus; transcription coactivator activity; transcription, DNA-dependent; ubiquitin binding; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding",PF00443;PF02148;,,,,,,,,,UBP16_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; histone deubiquitination [GO:0016578]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational elongation [GO:0045901]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp128246_c2_seq1,1498,37.0494,0.41813684,97,97,,9.00E-79,Q91W36,Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3),Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3),GO:0006281; GO:0008234; GO:0016578; GO:0000278; GO:0000790; GO:0031647; GO:0004221; GO:0006511; GO:0008270,DNA repair; cysteine-type peptidase activity; histone deubiquitination; mitotic cell cycle; nuclear chromatin; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF00443;PF02148;,6.00E-66,CHOYP_UBP3.1.1,,,,,,,UBP3_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128248_c0_seq1,928,41.8103,0.59368995,0,0,,2.00E-87,Q9V3R8,UbiA prenyltransferase domain-containing protein 1 homolog (EC 2.5.1.-) (Protein heixuedian),UbiA prenyltransferase domain-containing protein 1 homolog (EC 2.5.1.-) (Protein heixuedian),GO:0016021; GO:0016020; GO:0009234; GO:0031966; GO:0005739; GO:0004659,integral to membrane; membrane; menaquinone biosynthetic process; mitochondrial membrane; mitochondrion; prenyltransferase activity,PF01040;,,,,,,,,,UBIA1_DROME,Drosophila melanogaster (Fruit fly),larval lymph gland hemopoiesis [GO:0035167]; menaquinone biosynthetic process [GO:0009234]; mitochondrion morphogenesis [GO:0070584]; negative regulation of hemocyte proliferation [GO:0035207]; negative regulation of lamellocyte differentiation [GO:0035204]; regulation of hemocyte differentiation [GO:0045610]; regulation of JAK-STAT cascade [GO:0046425]; regulation of MAPK cascade [GO:0043408]; regulation of Ras protein signal transduction [GO:0046578]; regulation of Toll signaling pathway [GO:0008592] comp128248_c0_seq2,944,42.6907,0.56110899,1,3,,4.00E-87,Q9DC60,UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-),UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-),GO:0016209; GO:0072358; GO:0005783; GO:0005789; GO:0001885; GO:0030173; GO:0009234; GO:0005739; GO:0005634; GO:0004659; GO:0006744; GO:0042371,antioxidant activity; cardiovascular system development; endoplasmic reticulum; endoplasmic reticulum membrane; endothelial cell development; integral to Golgi membrane; menaquinone biosynthetic process; mitochondrion; nucleus; prenyltransferase activity; ubiquinone biosynthetic process; vitamin K biosynthetic process,PF01040;,9.00E-36,CHOYP_UBIA1.1.1,,,,,,,UBIA1_MOUSE,Mus musculus (Mouse),cardiovascular system development [GO:0072358]; endothelial cell development [GO:0001885]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]; vitamin K biosynthetic process [GO:0042371] comp128249_c1_seq3,1196,45.8194,0.27926241,32,0,,2.00E-24,O60673,DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3),DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3),GO:0051539; GO:0003677; GO:0006261; GO:0003887; GO:0005694; GO:0046872; GO:0000166; GO:0005634; GO:0019985; GO:0016035,"4 iron, 4 sulfur cluster binding; DNA binding; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; chromosome; metal ion binding; nucleotide binding; nucleus; translesion synthesis; zeta DNA polymerase complex",PF00136;PF03104;PF15735;PF14260;,2.00E-14,CHOYP_REV3L.1.1,,,,,,,DPOLZ_HUMAN,Homo sapiens (Human),DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] comp128251_c0_seq1,872,40.711,0.36461527,0,0,,1.00E-08,P56101,Cysteine string protein (CCCS1),DnaJ homolog subfamily C member 5 (CCCS1) (Cysteine string protein) (CSP),GO:0016020,membrane,PF00226;,,,,,,,,,CSP_TORCA,Tetronarce californica (Pacific electric ray) (Torpedo californica), comp128251_c0_seq2,1183,39.8986,0.36732634,14,61,,1.00E-48,O42196,Cysteine string protein (CSP) (Xcsp),DnaJ homolog subfamily C member 5 (Cysteine string protein) (CSP) (Xcsp),GO:0016020,membrane,PF00226;,3.00E-37,CHOYP_DNJC5.1.1,,,,,,,CSP_XENLA,Xenopus laevis (African clawed frog), comp128262_c0_seq1,1062,34.6516,0.5662292,20,422,,2.00E-12,O70131,Ninjurin-1 (Nerve injury-induced protein 1),Ninjurin-1 (Nerve injury-induced protein 1),GO:0007155; GO:0016021; GO:0042246,cell adhesion; integral to membrane; tissue regeneration,PF04923;,,,,,,,,,NINJ1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; hyaloid vascular plexus regression [GO:1990384]; positive regulation of cell-matrix adhesion [GO:0001954]; tissue regeneration [GO:0042246] comp128268_c0_seq1,817,45.6548,0.59534296,35,79,,2.00E-93,Q64674,Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase),Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase),GO:0008295; GO:0004766,spermidine biosynthetic process; spermidine synthase activity,,1.00E-59,CHOYP_LOC100641892.1.1,,,,,,,SPEE_MOUSE,Mus musculus (Mouse),spermidine biosynthetic process [GO:0008295] comp128269_c0_seq3,830,42.2892,0.69277812,5,0,,,,,,,,,6.00E-37,CHOYP_LOC100639369.1.1,,,,,,,,, comp128269_c0_seq4,1013,42.6456,0.65151277,6,7,,,,,,,,,8.00E-37,CHOYP_LOC100639369.1.1,,,,,,,,, comp128270_c0_seq1,727,40.1651,0.68611241,136,1387,,8.00E-51,Q4V842,G patch domain-containing protein 4,G patch domain-containing protein 4,GO:0003676,nucleic acid binding,PF01585;,1.00E-32,CHOYP_GPTC4.2.2,4.00E-36,ruditapes_c19539,,,,,GPTC4_XENLA,Xenopus laevis (African clawed frog), comp128271_c0_seq1,217,45.6221,1.47799749,25,5,,,,,,,,,,,6.00E-15,ruditapes_c27048,,,,,,, comp128277_c1_seq2,262,40.458,0.28922709,4,0,,2.00E-13,O34796,Uncharacterized phosphotransferase YvkC,Uncharacterized phosphotransferase YvkC,GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,6.00E-25,CHOYP_LOC100890479.1.3,,,,,,,YVKC_BACSU,Bacillus subtilis (strain 168), comp128284_c0_seq1,1309,45.6837,0.59735557,10,27,,1.00E-161,P50464,LIM domain-containing protein unc-97 (PINCH homolog) (Uncoordinated protein 97),LIM domain-containing protein unc-97 (PINCH homolog) (Uncoordinated protein 97),GO:0031430; GO:0005912; GO:0045216; GO:0007517; GO:0005634; GO:0050954; GO:0055120; GO:0008270,M band; adherens junction; cell-cell junction organization; muscle organ development; nucleus; sensory perception of mechanical stimulus; striated muscle dense body; zinc ion binding,PF00412;,0,CHOYP_LOC100123629.1.1,,,,,,,UNC97_CAEEL,Caenorhabditis elegans,cell-cell junction organization [GO:0045216]; muscle organ development [GO:0007517]; sensory perception of mechanical stimulus [GO:0050954] comp128284_c0_seq3,1011,47.5767,0.62048971,0,0,,2.00E-23,Q2KI95,Four and a half LIM domains protein 2 (FHL-2),Four and a half LIM domains protein 2 (FHL-2),GO:0015629; GO:0055014; GO:0005737; GO:0005925; GO:0060347; GO:0043066; GO:0000122; GO:0005634; GO:0001649; GO:0009725; GO:0008134; GO:0006351; GO:0055015; GO:0008270,"actin cytoskeleton; atrial cardiac muscle cell development; cytoplasm; focal adhesion; heart trabecula formation; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; osteoblast differentiation; response to hormone stimulus; transcription factor binding; transcription, DNA-dependent; ventricular cardiac muscle cell development; zinc ion binding",PF00412;,2.00E-87,CHOYP_BRAFLDRAFT_275732.1.1,,,,,,,FHL2_BOVIN,Bos taurus (Bovine),"atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]; ventricular cardiac muscle cell development [GO:0055015]" comp128285_c0_seq1,526,42.9658,0.33333454,30,21,,1.00E-102,Q9QXK7,Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73),Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73),GO:0008409; GO:0003723; GO:0004521; GO:0006398; GO:0005847; GO:0046872; GO:0030529,5'-3' exonuclease activity; RNA binding; endoribonuclease activity; histone mRNA 3'-end processing; mRNA cleavage and polyadenylation specificity factor complex; metal ion binding; ribonucleoprotein complex,PF10996;PF11718;PF00753;PF07521;,3.00E-114,CHOYP_BRAFLDRAFT_282200.1.1,,,,,,,CPSF3_MOUSE,Mus musculus (Mouse),mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398] comp128290_c0_seq1,938,45.2026,0.54472739,16,119,,7.00E-106,P06280,Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase),Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase),GO:0005794; GO:0004557; GO:0005576; GO:0016936; GO:0016139; GO:0046477; GO:0043202; GO:0045019; GO:0051001; GO:0009311; GO:0042803; GO:0052692; GO:0005102; GO:0044281,Golgi apparatus; alpha-galactosidase activity; extracellular region; galactoside binding; glycoside catabolic process; glycosylceramide catabolic process; lysosomal lumen; negative regulation of nitric oxide biosynthetic process; negative regulation of nitric-oxide synthase activity; oligosaccharide metabolic process; protein homodimerization activity; raffinose alpha-galactosidase activity; receptor binding; small molecule metabolic process,PF16499;,2.00E-25,CHOYP_LOC587840.1.1,,,,,,,AGAL_HUMAN,Homo sapiens (Human),glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] comp128293_c0_seq2,821,43.6054,0.64144678,2,18,,4.00E-34,Q4QQM4,Tumor protein p53-inducible protein 11 (Transformation related protein 53 inducible protein 11) (p53-induced gene 11 protein),Tumor protein p53-inducible protein 11 (Transformation related protein 53 inducible protein 11) (p53-induced gene 11 protein),GO:0016021,integral to membrane,PF14936;,8.00E-36,CHOYP_P5I11.1.1,,,,,,,P5I11_MOUSE,Mus musculus (Mouse), comp128293_c0_seq3,883,41.2231,0.69690811,0,17,,,,,,,,,2.00E-38,CHOYP_TP53I11.1.2,,,,,,,,, comp128299_c1_seq1,1324,42.6737,0.50080836,85,188,,,,,,,,,5.00E-66,CHOYP_BRAFLDRAFT_118756.1.2,,,,,,,,, comp128305_c0_seq2,654,35.1682,0.49904879,2,0,,,,,,,,,,,2.00E-15,ruditapes_c15855,,,,,,, comp128314_c1_seq1,730,43.9726,0.63270242,58,62,,3.00E-92,Q4R550,"Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)","Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)",GO:0005524; GO:0004817; GO:0006423; GO:0005737; GO:0046872; GO:0000049,ATP binding; cysteine-tRNA ligase activity; cysteinyl-tRNA aminoacylation; cytoplasm; metal ion binding; tRNA binding,PF01406;,4.00E-32,CHOYP_MYSP.5.9,,,,,,,SYCC_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cysteinyl-tRNA aminoacylation [GO:0006423] comp128318_c1_seq1,1075,44.2791,0.22795423,6,110,,5.00E-130,Q5RBU7,Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP),Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP),GO:0004180; GO:0005764; GO:0006508; GO:0008236,carboxypeptidase activity; lysosome; proteolysis; serine-type peptidase activity,PF05577;,,,,,,,,,PCP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp128318_c3_seq1,366,36.612,0.59842049,2,40,,,,,,,,,1.00E-41,CHOYP_PCP.1.1,,,,,,,,, comp128323_c2_seq2,630,41.2698,0.49715277,41,47,,3.00E-15,Q96T23,Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),GO:0034080; GO:0006352; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0005654; GO:0016584; GO:0045893; GO:0050434; GO:0008270,"CENP-A containing nucleosome assembly at centromere; DNA-dependent transcription, initiation; RSF complex; histone binding; negative regulation of DNA binding; negative regulation of transcription, DNA-dependent; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; positive regulation of viral transcription; zinc ion binding",PF00628;PF15612;,,,,,,,,,RSF1_HUMAN,Homo sapiens (Human),"CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]" comp128326_c0_seq1,1274,34.6154,0.44896254,31,166,,3.00E-23,Q9CR58,Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30),Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30),GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,3.00E-17,CHOYP_LOC584986.1.1,,,,,,,KMCP1_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transmembrane transport [GO:0055085] comp128327_c0_seq2,1098,44.4444,1.04654295,3,34,,2.00E-89,Q2PFX5,Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30),Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30),GO:0005509; GO:0006874; GO:0005737; GO:0030234; GO:0004341; GO:0005634; GO:0032781; GO:0050848; GO:0008270,calcium ion binding; cellular calcium ion homeostasis; cytoplasm; enzyme regulator activity; gluconolactonase activity; nucleus; positive regulation of ATPase activity; regulation of calcium-mediated signaling; zinc ion binding,PF08450;,3.00E-42,CHOYP_RGN.1.1,3.00E-78,ruditapes2_c71,,,,,RGN_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cellular calcium ion homeostasis [GO:0006874]; positive regulation of ATPase activity [GO:0032781]; regulation of calcium-mediated signaling [GO:0050848] comp128328_c0_seq1,466,49.5708,0.73527104,0,0,,6.00E-08,A4Q9F4,Tubulin polyglutamylase TTLL11 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 11),Tubulin polyglutamylase TTLL11 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 11),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0051013; GO:0018095,cilium; cytoplasm; ligase activity; microtubule basal body; microtubule severing; protein polyglutamylation,PF03133;,,,9.00E-11,ruditapes_c20263,,,,,TTL11_MOUSE,Mus musculus (Mouse),microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095] comp128328_c0_seq6,610,44.2623,0.73756028,0,0,,1.00E-07,A4Q9F4,Tubulin polyglutamylase TTLL11 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 11),Tubulin polyglutamylase TTLL11 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 11),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0051013; GO:0018095,cilium; cytoplasm; ligase activity; microtubule basal body; microtubule severing; protein polyglutamylation,PF03133;,,,,,,,,,TTL11_MOUSE,Mus musculus (Mouse),microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095] comp128336_c0_seq2,262,30.1527,1.14515456,7,57,,,,,,,,,2.00E-11,CHOYP_BRAFLDRAFT_82458.1.1,,,,,,,,, comp128337_c0_seq1,654,36.5443,0.93305061,1,0,,9.00E-18,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp128337_c0_seq2,1057,34.5317,0.94261221,29,0,,3.00E-21,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp128339_c0_seq1,1274,39.011,0.53172888,80,189,,0,Q5I085,Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16),Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16),GO:0072357; GO:0007049; GO:0051301; GO:0005737; GO:0005977; GO:0046872; GO:0050115; GO:0005634; GO:0004721; GO:0030155,PTW/PP1 phosphatase complex; cell cycle; cell division; cytoplasm; glycogen metabolic process; metal ion binding; myosin-light-chain-phosphatase activity; nucleus; phosphoprotein phosphatase activity; regulation of cell adhesion,PF00149;PF16891;,0,CHOYP_PP1B.2.3,2.00E-25,ruditapes_c17178,,,,,PP1B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; regulation of cell adhesion [GO:0030155] comp128348_c0_seq1,282,46.4539,0.53675402,2,29,,1.00E-32,P13866,Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1),Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1),GO:0016324; GO:0031526; GO:0005975; GO:0005911; GO:0005412; GO:0005887; GO:0050892; GO:0044281,apical plasma membrane; brush border membrane; carbohydrate metabolic process; cell-cell junction; glucose:sodium symporter activity; integral to plasma membrane; intestinal absorption; small molecule metabolic process,PF00474;,,,,,,,,,SC5A1_HUMAN,Homo sapiens (Human),glucose transport [GO:0015758]; hexose transport [GO:0008645]; intestinal D-glucose absorption [GO:0001951] comp128349_c0_seq1,754,43.634,1.0134246,6,190,,,,,,,,,,,1.00E-30,ruditapes_c8411,,,,,,, comp128350_c0_seq1,1873,39.8825,0.54269648,113,157,,2.00E-23,Q8NCX0,Coiled-coil domain-containing protein 150,Coiled-coil domain-containing protein 150,,,,3.00E-64,CHOYP_LOC586463.1.1,,,,,,,CC150_HUMAN,Homo sapiens (Human), comp128351_c1_seq1,1806,44.2968,0.52207081,9,0,,2.00E-112,Q39610,"Dynein alpha chain, flagellar outer arm (DHC alpha)","Dynein alpha chain, flagellar outer arm (DHC alpha)",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF00630;PF07646;PF12777;PF01833;,,,,,,,,,DYHA_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp128351_c1_seq2,1821,44.2065,0.50829505,19,0,,0,P23098,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC.1.3,,,,,,,DYHC_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp128353_c0_seq1,555,48.1081,0.50000162,0,0,,,,,,,,,2.00E-48,CHOYP_FUT8.1.1,,,,,,,,, comp128353_c0_seq2,1221,44.7993,0.54311148,78,13,,4.00E-117,Q6NVP8,"Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)","Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)",GO:0032580; GO:0036071; GO:0008424; GO:0016021; GO:0033578,Golgi cisterna membrane; N-glycan fucosylation; glycoprotein 6-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation in Golgi,PF14604;,4.00E-48,CHOYP_FUT8.1.1,,,,,,,FUT8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] comp128357_c0_seq1,286,27.972,0,47,222,,,,,,,,,,,3.00E-14,ruditapes_c19336,,,,,,, comp128359_c2_seq1,787,44.5997,0.54046726,0,0,,8.00E-54,C3XRY1,Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66),Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66),GO:0051864; GO:0032453; GO:0005506; GO:0045892; GO:0005634; GO:0006351,"histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K4 specific); iron ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF08007;,,,,,,,,,NO66_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),"chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-amino acid modification [GO:0018193]; post-translational protein modification [GO:0043687]; ribosome biogenesis [GO:0042254]; transcription, DNA-templated [GO:0006351]" comp128359_c2_seq2,787,44.3456,0.52068275,0,0,,7.00E-31,B0WMG3,Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (Histone lysine demethylase NO66),Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (Histone lysine demethylase NO66),GO:0051864; GO:0032453; GO:0005506; GO:0045892; GO:0005634; GO:0006351,"histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K4 specific); iron ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF08007;,3.00E-21,CHOYP_LOC577190.1.1,,,,,,,NO66_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),"histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp128365_c0_seq1,1520,40,0.35026498,29,237,,2.00E-21,Q9Y4W2,Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog),Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog),GO:0071339; GO:0005737; GO:0006364,MLL1 complex; cytoplasm; rRNA processing,PF04031;,,,,,,,,,LAS1L_HUMAN,Homo sapiens (Human),chromatin organization [GO:0006325]; endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]; rRNA processing [GO:0006364] comp128371_c0_seq1,798,37.0927,0.52447569,661,3020,,6.00E-44,Q0MQC1,"Acyl carrier protein, mitochondrial (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)","Acyl carrier protein, mitochondrial (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)",GO:0006633; GO:0005739; GO:0055114; GO:0070469,fatty acid biosynthetic process; mitochondrion; oxidation-reduction process; respiratory chain,PF00550;,2.00E-24,CHOYP_RS17.10.11,2.00E-46,ruditapes_lrc35032,,,,,ACPM_PONPY,Pongo pygmaeus (Bornean orangutan),fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114] comp128371_c0_seq2,807,37.0508,0.64127083,867,2663,,1.00E-18,O80800,"Acyl carrier protein 2, mitochondrial (MtACP-2) (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)","Acyl carrier protein 2, mitochondrial (MtACP-2) (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)",GO:0050897; GO:0006633; GO:0005759; GO:0055114; GO:0070469,cobalt ion binding; fatty acid biosynthetic process; mitochondrial matrix; oxidation-reduction process; respiratory chain,PF00550;,,,3.00E-38,ruditapes_c2214,,,,,ACPM2_ARATH,Arabidopsis thaliana (Mouse-ear cress),fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114] comp128399_c0_seq1,992,41.2298,0.45528521,80,14,,3.00E-08,Q4R3F0,Protein tilB homolog (Leucine-rich repeat-containing protein 6),Protein tilB homolog (Leucine-rich repeat-containing protein 6),GO:0005929; GO:0005737,cilium; cytoplasm,,5.00E-14,CHOYP_BRAFLDRAFT_124175.1.1,,,,,,,TILB_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp128416_c1_seq1,202,25.2475,0.31231535,10,0,,,,,,,,,,,6.00E-21,ruditapes_c19911,,,,,,, comp128419_c0_seq1,1283,42.8683,0.61516387,7,9,,1.00E-77,Q9BZF1,Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8),Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8),GO:0015485; GO:0045444; GO:0006869; GO:0010891; GO:0005543,cholesterol binding; fat cell differentiation; lipid transport; negative regulation of sequestering of triglyceride; phospholipid binding,PF01237;PF00169;,2.00E-76,CHOYP_OSBPL8.1.1,,,,,,,OSBL8_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] comp128421_c0_seq1,1149,44.7346,0.55037132,5,23,,9.00E-75,Q9Y6N9,Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein),Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein),GO:0000086; GO:0045177; GO:0042491; GO:0005737; GO:0005856; GO:0005829; GO:0050957; GO:0042472; GO:0030046; GO:0045494; GO:0001917; GO:0001750; GO:0005886; GO:0050953; GO:0007605; GO:0032420; GO:0045202,G2/M transition of mitotic cell cycle; apical part of cell; auditory receptor cell differentiation; cytoplasm; cytoskeleton; cytosol; equilibrioception; inner ear morphogenesis; parallel actin filament bundle assembly; photoreceptor cell maintenance; photoreceptor inner segment; photoreceptor outer segment; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilium; synapse,PF00595;,,,,,,,,,USH1C_HUMAN,Homo sapiens (Human),brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; cellular protein complex assembly [GO:0043623]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] comp128421_c0_seq2,534,44.382,0.66767229,8,1,,9.00E-12,Q925E0,Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5),Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5),GO:0005737; GO:0005856; GO:0005543; GO:0042383,cytoplasm; cytoskeleton; phospholipid binding; sarcolemma,PF00595;,,,,,,,,,SNTG2_MOUSE,Mus musculus (Mouse), comp128421_c0_seq3,1244,43.9711,0.52969742,15,11,,3.00E-13,Q8VBX6,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0007155; GO:0031410; GO:0030425; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; cell adhesion; cytoplasmic vesicle; dendrite; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,8.00E-57,CHOYP_USH1C.1.1,,,,,,,MPDZ_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; myelination [GO:0042552] comp128425_c0_seq1,988,48.1781,0.63557073,0,0,,1.00E-25,Q9UKP5,A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-),GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS6_HUMAN,Homo sapiens (Human),aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976] comp128425_c0_seq2,1789,49.3572,0.63522899,0,0,,2.00E-123,Q9P2N4,A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-),GO:0005615; GO:0006516; GO:0004222; GO:0008237; GO:0007275; GO:0045636; GO:0005578; GO:0006508; GO:0008270,extracellular space; glycoprotein catabolic process; metalloendopeptidase activity; metallopeptidase activity; multicellular organismal development; positive regulation of melanocyte differentiation; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF08685;PF01562;PF01421;PF00090;,,,,,,,,,ATS9_HUMAN,Homo sapiens (Human),glycoprotein catabolic process [GO:0006516]; multicellular organism development [GO:0007275]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; vesicle-mediated transport [GO:0016192] comp128425_c0_seq3,1784,48.0942,0.63035245,0,0,,7.00E-35,Q7TSK7,ADAMTS-like protein 2 (ADAMTSL-2) (TSP1-repeat-containing protein 1) (TCP-1),ADAMTS-like protein 2 (ADAMTSL-2) (TSP1-repeat-containing protein 1) (TCP-1),GO:0004222; GO:0005578; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; zinc ion binding,PF05986;PF08686;PF00090;,,,,,,,,,ATL2_MOUSE,Mus musculus (Mouse),extracellular matrix organization [GO:0030198]; lobar bronchus epithelium development [GO:0060481]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] comp128425_c0_seq4,1436,47.493,0.57722462,0,0,,4.00E-35,Q6ZMP0,Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6),Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6),GO:0048251; GO:0004222; GO:0001527,elastic fiber assembly; metalloendopeptidase activity; microfibril,PF05986;PF08686;PF00090;,,,,,,,,,THSD4_HUMAN,Homo sapiens (Human),elastic fiber assembly [GO:0048251] comp128425_c0_seq5,1441,49.0632,0.58713383,0,0,,3.00E-35,Q3UTY6,Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4),Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4),GO:0048251; GO:0004222; GO:0001527,elastic fiber assembly; metalloendopeptidase activity; microfibril,PF05986;PF08686;PF00090;,,,,,,,,,THSD4_MOUSE,Mus musculus (Mouse),elastic fiber assembly [GO:0048251] comp128425_c1_seq1,488,47.3361,0.77048643,25,5,,2.00E-10,Q61824,Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha),Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha),GO:0007155; GO:0016021; GO:0004222; GO:0005739; GO:0005634; GO:0005886; GO:0006508; GO:0008270,cell adhesion; integral to membrane; metalloendopeptidase activity; mitochondrion; nucleus; plasma membrane; proteolysis; zinc ion binding,PF08516;PF00200;PF01562;PF01421;,2.00E-33,CHOYP_ATS9.1.3,,,,,,,ADA12_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; epidermal growth factor receptor signaling pathway [GO:0007173] comp128425_c2_seq1,568,44.8944,0.59835643,23,11,,2.00E-53,Q8TE58,A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS15_HUMAN,Homo sapiens (Human), comp128425_c3_seq1,537,45.4376,0.47920687,22,29,,9.00E-50,P59510,A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-),GO:0030198; GO:0005615; GO:0004222; GO:0043066; GO:0045636; GO:0009967; GO:0005578; GO:0006508; GO:0008270,extracellular matrix organization; extracellular space; metalloendopeptidase activity; negative regulation of apoptotic process; positive regulation of melanocyte differentiation; positive regulation of signal transduction; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF08685;PF01562;PF01421;PF00090;,,,,,,,,,ATS20_HUMAN,Homo sapiens (Human),extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967] comp128425_c4_seq1,1087,47.7461,0.7032233,43,27,,3.00E-63,Q19791,A disintegrin and metalloproteinase with thrombospondin motifs gon-1 (ADAMTS gon-1) (EC 3.4.24.-) (Abnormal gonad development protein 1),A disintegrin and metalloproteinase with thrombospondin motifs gon-1 (ADAMTS gon-1) (EC 3.4.24.-) (Abnormal gonad development protein 1),GO:0006888; GO:0005604; GO:0005623; GO:0016477; GO:0008406; GO:0004222; GO:0008237; GO:0006508; GO:0008270,ER to Golgi vesicle-mediated transport; basement membrane; cell; cell migration; gonad development; metalloendopeptidase activity; metallopeptidase activity; proteolysis; zinc ion binding,PF05986;PF08685;PF01421;PF00090;,,,,,,,,,GON1_CAEEL,Caenorhabditis elegans,cell migration [GO:0016477]; ER to Golgi vesicle-mediated transport [GO:0006888]; gonad development [GO:0008406]; protein transport [GO:0015031] comp128427_c0_seq1,1231,40.4549,0.42521188,135,94,,7.00E-85,O00170,AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9),AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9),GO:0036004; GO:0005829; GO:0016020; GO:0051344; GO:0005634; GO:0022417; GO:0006626; GO:0010738; GO:0004871; GO:0003713; GO:0008134; GO:0051082; GO:0006805,GAF domain binding; cytosol; membrane; negative regulation of cyclic-nucleotide phosphodiesterase activity; nucleus; protein maturation by protein folding; protein targeting to mitochondrion; regulation of protein kinase A signaling cascade; signal transducer activity; transcription coactivator activity; transcription factor binding; unfolded protein binding; xenobiotic metabolic process,PF00254;,1.00E-41,CHOYP_LOC658248.1.1,,,,,,,AIP_HUMAN,Homo sapiens (Human),negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; protein maturation by protein folding [GO:0022417]; protein targeting to mitochondrion [GO:0006626]; regulation of protein kinase A signaling [GO:0010738]; xenobiotic metabolic process [GO:0006805] comp128450_c0_seq1,1311,41.1899,1.02787459,5,0,,3.00E-19,Q9HCC6,Transcription factor HES-4 (hHES4) (Class B basic helix-loop-helix protein 42) (bHLHb42) (Hairy and enhancer of split 4) (bHLH factor Hes4),Transcription factor HES-4 (hHES4) (Class B basic helix-loop-helix protein 42) (bHLHb42) (Hairy and enhancer of split 4) (bHLH factor Hes4),GO:0003677; GO:0030154; GO:0007399; GO:0005634; GO:0006355; GO:0008134; GO:0006351,"DNA binding; cell differentiation; nervous system development; nucleus; regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF07527;PF00010;,,,,,,,,,HES4_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128454_c0_seq1,697,38.7374,0.49813453,33,100,,3.00E-44,Q8K2H6,Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10),Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10),GO:0005680; GO:0031145; GO:0051301; GO:0005737; GO:0007067; GO:0070979; GO:0030071,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cytoplasm; mitosis; protein K11-linked ubiquitination; regulation of mitotic metaphase/anaphase transition,PF03256;,7.00E-48,CHOYP_LOC100642984.1.1,,,,,,,APC10_MOUSE,Mus musculus (Mouse),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071] comp128459_c0_seq1,758,39.1821,0.3808857,12,109,,6.00E-07,B7U179,ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1),ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1),GO:0031261; GO:0006261; GO:2000104; GO:0008285; GO:0016567,DNA replication preinitiation complex; DNA-dependent DNA replication; negative regulation of DNA-dependent DNA replication; negative regulation of cell proliferation; protein ubiquitination,PF00514;PF00651;,,,,,,,,,ABAP1_ARATH,Arabidopsis thaliana (Mouse-ear cress),DNA-dependent DNA replication [GO:0006261]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA-dependent DNA replication [GO:2000104]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127] comp128462_c0_seq1,2251,38.8272,0.52624737,6679,19142,,1.00E-140,P22232,rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-),rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase),GO:0003723; GO:0008168; GO:0005730; GO:0006364; GO:0030529; GO:0008033,RNA binding; methyltransferase activity; nucleolus; rRNA processing; ribonucleoprotein complex; tRNA processing,PF01269;,2.00E-161,CHOYP_LOC591797.3.3,,,,,,,FBRL_XENLA,Xenopus laevis (African clawed frog),histone glutamine methylation [GO:1990258]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033] comp128465_c0_seq1,861,36.1208,0.83044428,8,146,,9.00E-08,Q8R4S0,Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein),Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein),GO:0005737; GO:0012505; GO:0016020; GO:0004865; GO:0042325; GO:0007165,cytoplasm; endomembrane system; membrane; protein serine/threonine phosphatase inhibitor activity; regulation of phosphorylation; signal transduction,PF05361;,5.00E-26,CHOYP_RALA.4.4,,,,,,,PP14C_MOUSE,Mus musculus (Mouse),regulation of phosphorylation [GO:0042325]; regulation of protein dephosphorylation [GO:0035304]; signal transduction [GO:0007165] comp128470_c0_seq1,1136,33.8028,0.43754844,28,132,,4.00E-32,Q9Y5L0,Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR),Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR),GO:0005737; GO:0005634; GO:0004872; GO:0035048,cytoplasm; nucleus; receptor activity; splicing factor protein import into nucleus,PF08389;,1.00E-15,CHOYP_TNPO3.1.1,,,,,,,TNPO3_HUMAN,Homo sapiens (Human),splicing factor protein import into nucleus [GO:0035048] comp128473_c0_seq1,629,35.4531,0.46285831,16,0,,5.00E-34,Q96Q77,Calcium and integrin-binding family member 3 (Kinase-interacting protein 3) (KIP 3),Calcium and integrin-binding family member 3 (Kinase-interacting protein 3) (KIP 3),GO:0005509,calcium ion binding,PF13499;,3.00E-26,CHOYP_TSP_08109.1.1,,,,,,,CIB3_HUMAN,Homo sapiens (Human), comp128476_c0_seq1,456,41.0088,0.52456634,9,77,,1.00E-06,Q7JQ07,Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),GO:0003677; GO:0015074; GO:0006310; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA integration; DNA recombination; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF01359;,,,,,,,,,MOS1T_DROMA,Drosophila mauritiana (Fruit fly),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp128477_c0_seq1,415,28.9157,1.39637174,25,140,,1.00E-18,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,9.00E-25,CHOYP_LOC100536242.1.1,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp128482_c0_seq1,628,35.6688,0.65269961,14,81,,1.00E-34,Q14584,Zinc finger protein 266 (Zinc finger protein HZF1),Zinc finger protein 266 (Zinc finger protein HZF1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN266_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128490_c0_seq1,1247,39.8557,0.95189935,32,303,,2.00E-09,Q3UHJ8,RING finger protein 44,RING finger protein 44,GO:0008270,zinc ion binding,PF13639;,,,3.00E-35,ruditapes2_c2501,,,,,RNF44_MOUSE,Mus musculus (Mouse),"proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of transcription, DNA-templated [GO:0006355]" comp128491_c0_seq1,945,47.0899,0.47773971,4,5,,8.00E-06,Q62682,Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1),Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1),GO:0046658; GO:0016337; GO:0007399,anchored to plasma membrane; cell-cell adhesion; nervous system development,PF00041;PF07679;,,,,,,,,,CNTN3_RAT,Rattus norvegicus (Rat),nervous system development [GO:0007399]; single organismal cell-cell adhesion [GO:0016337] comp128491_c0_seq2,1013,41.9546,0.51711802,7,14,,6.00E-07,Q9JM58,Cytokine receptor-like factor 1 (Cytokine receptor-like molecule 3) (CRLM-3) (Cytokine-like factor 1) (CLF-1) (Novel cytokine receptor 6) (NR6),Cytokine receptor-like factor 1 (Cytokine receptor-like molecule 3) (CRLM-3) (Cytokine-like factor 1) (CLF-1) (Novel cytokine receptor 6) (NR6),GO:0097058; GO:0005737; GO:2000672; GO:0005886; GO:0008284; GO:0042517; GO:0046982; GO:0001657,CRLF-CLCF1 complex; cytoplasm; negative regulation of motor neuron apoptotic process; plasma membrane; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein; protein heterodimerization activity; ureteric bud development,PF09067;PF00041;,,,,,,,,,CRLF1_MOUSE,Mus musculus (Mouse),negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell proliferation [GO:0008284]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; ureteric bud development [GO:0001657] comp128491_c0_seq5,794,47.6071,0.46801487,2,0,,2.00E-07,Q2EY14,Protogenin A,Protogenin A,GO:0016021; GO:0007275,integral to membrane; multicellular organismal development,PF00041;PF07679;,,,,,,,,,PRTGA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),multicellular organism development [GO:0007275] comp128492_c0_seq2,1135,36.9163,0.27223948,0,8,,3.00E-18,A2AIW0,Serologically defined colon cancer antigen 3 homolog,Serologically defined colon cancer antigen 3 homolog,GO:0005737,cytoplasm,,,,,,,,,,SDCG3_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; cell division [GO:0051301]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp128493_c0_seq1,819,41.514,0.34248772,5255,19554,,2.00E-57,B2B9A1,"ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP)","ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP)",GO:0015986; GO:0005753; GO:0046933,"ATP synthesis coupled proton transport; mitochondrial proton-transporting ATP synthase complex; proton-transporting ATP synthase activity, rotational mechanism",PF00213;,,,8.00E-40,ruditapes2_c516,,,,,ATPO_RHIFE,Rhinolophus ferrumequinum (Greater horseshoe bat),ATP synthesis coupled proton transport [GO:0015986] comp128494_c0_seq1,1169,44.8246,0.51279841,90,117,,3.00E-22,Q6ZNA5,Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),GO:0000293; GO:0016021; GO:0046872,ferric-chelate reductase activity; integral to membrane; metal ion binding,PF03351;PF02014;,1.00E-22,CHOYP_DYAK_GE11746.1.1,,,,,,,FRRS1_HUMAN,Homo sapiens (Human), comp128494_c1_seq1,1066,38.8368,0.57989181,56,36,,3.00E-12,Q9P0K9,DOMON domain-containing protein FRRS1L (Brain protein CG-6) (Ferric-chelate reductase 1-like protein),DOMON domain-containing protein FRRS1L (Brain protein CG-6) (Ferric-chelate reductase 1-like protein),GO:0030054; GO:0016021; GO:0005886; GO:0045202,cell junction; integral to membrane; plasma membrane; synapse,PF03351;,,,,,,,,,FRS1L_HUMAN,Homo sapiens (Human), comp128499_c0_seq1,379,43.7995,1.1163415,11,19,,8.00E-61,Q9UGP5,DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase beta-2) (Pol beta2) (DNA polymerase kappa),DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase beta-2) (Pol beta2) (DNA polymerase kappa),GO:0003677; GO:0006260; GO:0003887; GO:0016829; GO:0046872; GO:0006289; GO:0005634; GO:0016446,DNA binding; DNA replication; DNA-directed DNA polymerase activity; lyase activity; metal ion binding; nucleotide-excision repair; nucleus; somatic hypermutation of immunoglobulin genes,PF14792;PF14791;PF10391;PF14716;,2.00E-59,CHOYP_BRAFLDRAFT_235602.1.1,,,,,,,DPOLL_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp128500_c0_seq1,1704,39.3192,0.88534983,3141,468,,3.00E-17,Q2QL80,Caveolin-2,Caveolin-2,GO:0031748; GO:0000139; GO:0005901; GO:0070836; GO:0007029; GO:0031234; GO:0007005; GO:0001937; GO:0005634; GO:0048471; GO:0060161; GO:0048741; GO:0048278; GO:0006906,D1 dopamine receptor binding; Golgi membrane; caveola; caveola assembly; endoplasmic reticulum organization; extrinsic to internal side of plasma membrane; mitochondrion organization; negative regulation of endothelial cell proliferation; nucleus; perinuclear region of cytoplasm; positive regulation of dopamine receptor signaling pathway; skeletal muscle fiber development; vesicle docking; vesicle fusion,PF01146;,,,,,,,,,CAV2_DIDVI,Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana),caveola assembly [GO:0070836]; endoplasmic reticulum organization [GO:0007029]; mitochondrion organization [GO:0007005]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; skeletal muscle fiber development [GO:0048741]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] comp128505_c0_seq1,1072,34.1418,0.28960889,18,252,,7.00E-08,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp128513_c0_seq1,3571,37.6085,0.57053112,2457,176,,,,,,,,,0,CHOYP_LOC100181355.1.1,,,,,,,,, comp128513_c0_seq2,2731,39.4361,0.54672811,0,6,,,,,,,,,0,CHOYP_LOC100181355.1.1,,,,,,,,, comp128513_c0_seq3,2891,39.6057,0.54706557,1,0,,3.00E-164,A6H782,Tektin-3,Tektin-3,GO:0035085; GO:0005874; GO:0000226,cilium axoneme; microtubule; microtubule cytoskeleton organization,,0,CHOYP_TEKT5.1.1,,,,,,,TEKT3_BOVIN,Bos taurus (Bovine),cilium morphogenesis [GO:0060271]; regulation of fertilization [GO:0080154]; sperm motility [GO:0030317] comp128522_c0_seq1,1368,34.3567,0.70339145,629,7783,,1.00E-57,P28757,Superoxide dismutase [Cu-Zn] 2 (EC 1.15.1.1),Superoxide dismutase [Cu-Zn] 2 (EC 1.15.1.1),GO:0005507; GO:0005737; GO:0019430; GO:0004784; GO:0008270,copper ion binding; cytoplasm; removal of superoxide radicals; superoxide dismutase activity; zinc ion binding,PF00080;,,,,,,,,,SODC2_ORYSJ,Oryza sativa subsp. japonica (Rice),removal of superoxide radicals [GO:0019430] comp128522_c0_seq2,1349,34.2476,0.6932693,680,7307,,1.00E-66,O73872,Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),GO:0005507; GO:0005829; GO:0005739; GO:0070050; GO:0005634; GO:0019430; GO:0010038; GO:0051597; GO:0009410; GO:0004784; GO:0008270,copper ion binding; cytosol; mitochondrion; neuron cellular homeostasis; nucleus; removal of superoxide radicals; response to metal ion; response to methylmercury; response to xenobiotic stimulus; superoxide dismutase activity; zinc ion binding,PF00080;,1.00E-29,CHOYP_ISCW_ISCW008219.1.2,4.00E-39,ruditapes_c7557,,,,,SODC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),neuron cellular homeostasis [GO:0070050]; response to metal ion [GO:0010038]; response to methylmercury [GO:0051597]; response to xenobiotic stimulus [GO:0009410] comp128528_c0_seq2,666,45.045,0.92593465,1,16,,,,,,,,,,,1.00E-43,ruditapes_c5883,,,,,,, comp128528_c1_seq1,247,49.3927,0.62001016,8,0,,,,,,,,,5.00E-13,CHOYP_NEMVEDRAFT_V1G247993.1.1,,,,,,,,, comp128530_c1_seq1,879,42.2071,0.48618847,0,0,,,,,,,,,6.00E-101,CHOYP_ISCW_ISCW010750.1.1,,,,,,,,, comp128530_c1_seq2,992,42.7419,0.48660257,11,14,,3.00E-174,Q4KLL4,Transmembrane 9 superfamily member 4,Transmembrane 9 superfamily member 4,GO:0016021,integral to membrane,PF02990;,0,CHOYP_TM9S4.1.1,3.00E-27,ruditapes_c20807,,,,,TM9S4_RAT,Rattus norvegicus (Rat), comp128531_c0_seq1,1422,41.4205,0.9785203,16,20,,7.00E-118,B0JYW5,Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT6) (EC 2.1.1.125),Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT6),GO:0006281; GO:0042393; GO:0070612; GO:0070611; GO:0044020; GO:0045892; GO:0005634; GO:0035242; GO:0035241; GO:0006351,"DNA repair; histone binding; histone methyltransferase activity (H2A-R3 specific); histone methyltransferase activity (H3-R2 specific); histone methyltransferase activity (H4-R3 specific); negative regulation of transcription, DNA-dependent; nucleus; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; transcription, DNA-dependent",PF05185;,1.00E-55,CHOYP_LOC591167.1.1,,,,,,,ANM6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"DNA repair [GO:0006281]; histone H3-R2 methylation [GO:0034970]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128531_c0_seq2,1312,40.1677,0.89592096,3,21,,9.00E-08,Q9XW42,Protein arginine N-methyltransferase 7 (EC 2.1.1.-),Protein arginine N-methyltransferase 7 (EC 2.1.1.-),GO:0008168; GO:0006479,methyltransferase activity; protein methylation,,,,,,,,,,ANM7_CAEEL,Caenorhabditis elegans,"peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of transcription, DNA-templated [GO:0006355]" comp128540_c0_seq3,269,49.0706,0.96729304,2,0,,,,,,,,,5.00E-19,CHOYP_LOC100175166.1.1,,,,,,,,, comp128541_c1_seq1,360,34.1667,0.49779755,11,4,,2.00E-07,Q62806,Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89),Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89),GO:0005794; GO:0003690; GO:0007276; GO:0046872; GO:0000122; GO:0005634; GO:0045944; GO:0006461; GO:0003700; GO:0000976; GO:0006351,"Golgi apparatus; double-stranded DNA binding; gamete generation; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein complex assembly; sequence-specific DNA binding transcription factor activity; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",,,,,,,,,,ZN148_RAT,Rattus norvegicus (Rat),"gamete generation [GO:0007276]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein complex assembly [GO:0006461]; substantia nigra development [GO:0021762]; transcription, DNA-templated [GO:0006351]" comp128541_c3_seq1,378,37.8307,0.63088248,18,2,,8.00E-08,Q5REK1,Zinc finger protein 136,Zinc finger protein 136,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF13912;,,,,,,,,,ZN136_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128545_c0_seq1,696,42.6724,0.9970028,23,202,,7.00E-48,A8IW99,Mitochondrial cardiolipin hydrolase (EC 3.1.-.-) (Phospholipase D6 homolog) (PLD 6),Mitochondrial cardiolipin hydrolase (EC 3.1.-.-) (Phospholipase D6 homolog) (PLD 6),GO:0004519; GO:0016021; GO:0016042; GO:0007126; GO:0046872; GO:0005741; GO:0090305,endonuclease activity; integral to membrane; lipid catabolic process; meiosis; metal ion binding; mitochondrial outer membrane; nucleic acid phosphodiester bond hydrolysis,PF13091;,,,6.00E-47,ruditapes_c30802,,,,,PLD6_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cardiolipin biosynthetic process [GO:0032049]; lipid catabolic process [GO:0016042]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587] comp128553_c0_seq2,544,33.6397,0.33935358,6,80,,,,,,,,,6.00E-16,CHOYP_BRAFLDRAFT_275631.1.1,,,,,,,,, comp128553_c1_seq1,448,39.5089,0.64562413,14,19,,7.00E-22,Q6NYP0,Transmembrane protein 208,Transmembrane protein 208,GO:0006914; GO:0005789; GO:0016021,autophagy; endoplasmic reticulum membrane; integral to membrane,PF05620;,,,,,,,,,TM208_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),autophagy [GO:0006914]; vacuolar protein processing [GO:0006624] comp128559_c0_seq1,2571,37.8063,0.56936577,233,271,,4.00E-110,D3YZP9,Coiled-coil domain-containing protein 6,Coiled-coil domain-containing protein 6,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF09755;,8.00E-143,CHOYP_CCDC6.1.1,,,,,,,CCDC6_MOUSE,Mus musculus (Mouse), comp128562_c0_seq2,1417,44.1778,0.66586395,0,0,,1.00E-24,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,,,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp128562_c0_seq3,725,42.069,0.81362224,0,0,,1.00E-07,B2KI42,Cadherin-2 (Neural cadherin) (N-cadherin) (CD antigen CD325),Cadherin-2 (Neural cadherin) (N-cadherin) (CD antigen CD325),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;PF08758;,,,,,,,,,CADH2_RHIFE,Rhinolophus ferrumequinum (Greater horseshoe bat),cell-cell adhesion mediated by cadherin [GO:0044331]; glial cell differentiation [GO:0010001]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuronal stem cell population maintenance [GO:0097150]; regulation of signal transduction [GO:0009966] comp128562_c0_seq4,1388,45.1729,0.59365046,0,0,,2.00E-18,Q9V5N8,Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),GO:0004930; GO:0007464; GO:0048057; GO:0016055; GO:0007411; GO:0005509; GO:0016339; GO:0050839; GO:0005911; GO:0048813; GO:0070593; GO:0007156; GO:0005887; GO:0016319; GO:0030178; GO:0007218; GO:0016318; GO:0030177; GO:0005057; GO:0050770; GO:0090175; GO:0051963; GO:0035159; GO:0007367; GO:0004888,"G-protein coupled receptor activity; R3/R4 cell fate commitment; R3/R4 development; Wnt receptor signaling pathway; axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell junction; dendrite morphogenesis; dendrite self-avoidance; homophilic cell adhesion; integral to plasma membrane; mushroom body development; negative regulation of Wnt receptor signaling pathway; neuropeptide signaling pathway; ommatidial rotation; positive regulation of Wnt receptor signaling pathway; receptor signaling protein activity; regulation of axonogenesis; regulation of establishment of planar polarity; regulation of synapse assembly; regulation of tube length, open tracheal system; segment polarity determination; transmembrane signaling receptor activity",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,2.00E-13,CHOYP_MBCDH18.1.1,,,,,,,STAN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]" comp128566_c0_seq1,859,43.539,0.52026689,23,122,,2.00E-47,Q96BJ8,Engulfment and cell motility protein 3,Engulfment and cell motility protein 3,GO:0006915; GO:0005737; GO:0005856; GO:0006909; GO:0005543,apoptotic process; cytoplasm; cytoskeleton; phagocytosis; phospholipid binding,PF11841;PF04727;PF16457;,,,5.00E-17,ruditapes_c10365,,,,,ELMO3_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell migration [GO:0016477]; phagocytosis [GO:0006909] comp128568_c1_seq1,626,42.6518,0.63583261,3,52,,2.00E-68,A6NK53,Zinc finger protein 233,Zinc finger protein 233,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,8.00E-15,CHOYP_ZNF836.1.1,,,,,,,ZN233_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128570_c0_seq1,2229,40.6909,0.42443861,312,1549,,3.00E-92,Q9Y6J9,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha),TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha),GO:0003677; GO:0006352; GO:0030914; GO:0006338; GO:0043966; GO:0000118; GO:0051090; GO:0006357; GO:0003713,"DNA binding; DNA-dependent transcription, initiation; STAGA complex; chromatin remodeling; histone H3 acetylation; histone deacetylase complex; regulation of sequence-specific DNA binding transcription factor activity; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity",PF02969;PF07571;,,,,,,,,,TAF6L_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter [GO:0006357]" comp128577_c0_seq1,955,38.8482,0.38118064,59,168,,2.00E-97,Q5ZL74,Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1),Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1),GO:0006888; GO:0005794; GO:0043001; GO:0031201; GO:0045177; GO:0017156; GO:0030054; GO:0005789; GO:0008333; GO:0043308; GO:0016021; GO:0031902; GO:0005765; GO:0043005; GO:0043312; GO:0048471; GO:0045335; GO:0030670; GO:0006911; GO:1900483; GO:0045202; GO:0030658; GO:0006906,"ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi to plasma membrane protein transport; SNARE complex; apical part of cell; calcium ion-dependent exocytosis; cell junction; endoplasmic reticulum membrane; endosome to lysosome transport; eosinophil degranulation; integral to membrane; late endosome membrane; lysosomal membrane; neuron projection; neutrophil degranulation; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; phagocytosis, engulfment; regulation of protein targeting to vacuolar membrane; synapse; transport vesicle membrane; vesicle fusion",PF13774;PF00957;,3.00E-118,CHOYP_BRAFLDRAFT_215087.1.1,,,,,,,VAMP7_CHICK,Gallus gallus (Chicken),"calcium ion regulated exocytosis [GO:0017156]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; Golgi to plasma membrane protein transport [GO:0043001]; natural killer cell degranulation [GO:0043320]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of histamine secretion by mast cell [GO:1903595]; regulation of protein targeting to vacuolar membrane [GO:1900483]; SNARE complex assembly [GO:0035493]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]" comp128578_c0_seq1,976,35.5533,0.81101358,6794,9119,,5.00E-08,Q02365,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (Complex I-B12) (CI-B12) (NADH-ubiquinone oxidoreductase B12 subunit),NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (Complex I-B12) (CI-B12) (NADH-ubiquinone oxidoreductase B12 subunit),GO:0022900; GO:0016021; GO:0005747,electron transport chain; integral to membrane; mitochondrial respiratory chain complex I,PF08122;,,,,,,,,,NDUB3_BOVIN,Bos taurus (Bovine),electron transport chain [GO:0022900] comp128579_c0_seq1,1114,41.0233,0.28961062,0,6,,1.00E-09,Q09715,Transcriptional repressor tup11,Transcriptional repressor tup11,GO:0006342; GO:0005829; GO:0042393; GO:0045014; GO:0000122; GO:0000790; GO:0043234; GO:0003714; GO:0006351,"chromatin silencing; cytosol; histone binding; negative regulation of transcription by glucose; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein complex; transcription corepressor activity; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP11_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp128579_c0_seq2,1108,40.8845,0.29230388,11,30,,2.00E-94,Q6DRF9,WD repeat-containing protein 55,WD repeat-containing protein 55,GO:0001654; GO:0005730; GO:0060465; GO:0006364; GO:0048794; GO:0048538,eye development; nucleolus; pharynx development; rRNA processing; swim bladder development; thymus development,PF12894;,4.00E-66,CHOYP_BRAFLDRAFT_69729.1.1,,,,,,,WDR55_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),eye development [GO:0001654]; pharynx development [GO:0060465]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; swim bladder development [GO:0048794]; thymus development [GO:0048538] comp128580_c1_seq1,1245,39.3574,0.3291886,83,115,,7.00E-35,Q52KK4,H/ACA ribonucleoprotein complex non-core subunit NAF1,H/ACA ribonucleoprotein complex non-core subunit NAF1,GO:0003723; GO:0030054; GO:0005813; GO:0005737; GO:0005634; GO:0001522; GO:0006364; GO:0042254; GO:0005732,RNA binding; cell junction; centrosome; cytoplasm; nucleus; pseudouridine synthesis; rRNA processing; ribosome biogenesis; small nucleolar ribonucleoprotein complex,PF04410;,1.00E-35,CHOYP_NAF1.1.1,,,,,,,NAF1_RAT,Rattus norvegicus (Rat),pseudouridine synthesis [GO:0001522]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] comp128593_c0_seq1,1173,43.4783,0.23474239,10,8,,5.00E-33,Q0P5X1,Leucine-rich repeat and IQ domain-containing protein 1,Leucine-rich repeat and IQ domain-containing protein 1,,,PF00612;PF13855;,6.00E-26,CHOYP_LRRIQ1.1.1,,,,,,,LRIQ1_MOUSE,Mus musculus (Mouse), comp128595_c0_seq1,1865,39.6783,0.47008105,0,3,,4.00E-124,Q501Z5,"tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)","tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)",GO:0005525; GO:0003924; GO:0005739; GO:0006400,GTP binding; GTPase activity; mitochondrion; tRNA modification,PF01926;PF12631;PF10396;,4.00E-31,CHOYP_BRAFLDRAFT_125232.1.1,,,,,,,GTPB3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] comp128595_c0_seq3,1944,39.6091,0.4659194,3,5,,9.00E-124,Q501Z5,"tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)","tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)",GO:0005525; GO:0003924; GO:0005739; GO:0006400,GTP binding; GTPase activity; mitochondrion; tRNA modification,PF01926;PF12631;PF10396;,,,,,,,,,GTPB3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] comp128597_c0_seq1,1840,36.9565,0.51363967,1488,5300,,8.00E-129,P92177,14-3-3 protein epsilon (Suppressor of Ras1 3-9),14-3-3 protein epsilon (Suppressor of Ras1 3-9),GO:0007411; GO:0005694; GO:0005737; GO:0008340; GO:0007294; GO:0045172; GO:0005875; GO:0007095; GO:0005634; GO:0008103; GO:0007280; GO:0045927; GO:0007088; GO:0009411; GO:0048190,axon guidance; chromosome; cytoplasm; determination of adult lifespan; germarium-derived oocyte fate determination; germline ring canal; microtubule associated complex; mitotic G2 DNA damage checkpoint; nucleus; oocyte microtubule cytoskeleton polarization; pole cell migration; positive regulation of growth; regulation of mitosis; response to UV; wing disc dorsal/ventral pattern formation,PF00244;,7.00E-110,CHOYP_1433E.2.2,3.00E-42,ruditapes_c29829,,,,,1433E_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint [GO:0000077]; germarium-derived oocyte fate determination [GO:0007294]; imaginal disc development [GO:0007444]; mitotic cell cycle checkpoint [GO:0007093]; mitotic G2 DNA damage checkpoint [GO:0007095]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole cell migration [GO:0007280]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of growth [GO:0045927]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of growth [GO:0040008]; regulation of mitotic nuclear division [GO:0007088]; response to radiation [GO:0009314]; response to UV [GO:0009411]; wing disc dorsal/ventral pattern formation [GO:0048190] comp128605_c0_seq1,1179,43.257,1.02954081,1288,3,male>female,5.00E-47,O42282,Photoreceptor outer segment membrane glycoprotein 2 (CRDS2),Photoreceptor outer segment membrane glycoprotein 2 (CRDS2),GO:0016021; GO:0007601,integral to membrane; visual perception,PF00335;,,,,,,,,,RDS2_CHICK,Gallus gallus (Chicken),visual perception [GO:0007601] comp128611_c0_seq1,1709,43.5342,0.48209074,2932,58,,2.00E-67,Q2T9T0,Protein phosphatase 1 regulatory subunit 32,Protein phosphatase 1 regulatory subunit 32,GO:0019902,phosphatase binding,PF15691;,5.00E-105,CHOYP_BRAFLDRAFT_100695.1.1,,,,,,,PPR32_BOVIN,Bos taurus (Bovine), comp128615_c1_seq1,850,45.2941,0.35276122,3,30,,5.00E-40,Q568M3,Cytokine receptor-like factor 3 (Clf-3 protein),Cytokine receptor-like factor 3 (Clf-3 protein),GO:0005737,cytoplasm,,,,,,,,,,CRLF3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp128616_c0_seq2,1612,42.7419,0.85654714,70,185,,3.00E-19,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp128616_c0_seq3,528,45.2652,0.96397879,3,0,,2.00E-07,Q54KH3,Ankyrin repeat domain-containing protein 39 homolog,Ankyrin repeat domain-containing protein 39 homolog,,,PF12796;,,,,,,,,,ANR39_DICDI,Dictyostelium discoideum (Slime mold), comp128618_c0_seq1,1061,42.4128,0.55597665,79,157,,5.00E-06,Q6P3G4,"Centriole, cilia and spindle-associated protein","Centriole, cilia and spindle-associated protein",GO:0030424; GO:0007420; GO:0005814; GO:0035869; GO:0035085; GO:0036064; GO:0003341; GO:0061371; GO:0060548; GO:0045930; GO:0048666; GO:0060296; GO:0045995; GO:0005819,axon; brain development; centriole; ciliary transition zone; cilium axoneme; cilium basal body; cilium movement; determination of heart left/right asymmetry; negative regulation of cell death; negative regulation of mitotic cell cycle; neuron development; regulation of cilium beat frequency involved in ciliary motility; regulation of embryonic development; spindle,PF15748;,,,,,,,,,CCSAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),brain development [GO:0007420]; cell division [GO:0051301]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; heart development [GO:0007507]; mitotic nuclear division [GO:0007067]; mitotic spindle microtubule depolymerization [GO:1990755]; negative regulation of cell death [GO:0060548]; negative regulation of mitotic cell cycle [GO:0045930]; neuron development [GO:0048666]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of embryonic development [GO:0045995]; regulation of mitotic spindle assembly [GO:1901673] comp128625_c0_seq4,783,40.3576,0.25128246,0,0,,4.00E-15,Q8IW19,Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1),Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1),GO:0008408; GO:0003906; GO:0005829; GO:0006302; GO:0004520; GO:0046872; GO:0000166; GO:0005634; GO:0000012,3'-5' exonuclease activity; DNA-(apurinic or apyrimidinic site) lyase activity; cytosol; double-strand break repair; endodeoxyribonuclease activity; metal ion binding; nucleotide binding; nucleus; single strand break repair,PF10283;,,,,,,,,,APLF_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; positive regulation of DNA ligation [GO:0051106]; regulation of isotype switching [GO:0045191]; single strand break repair [GO:0000012] comp128632_c0_seq1,1153,38.8552,0.41730986,67,221,,2.00E-58,Q6NUH3,Nitric oxide synthase-interacting protein,Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 6.3.2.-),GO:0005737; GO:0005634,cytoplasm; nucleus,PF15906;,3.00E-55,CHOYP_LOC725565.1.1,,,,,,,NOSIP_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; regulation of nitric-oxide synthase activity [GO:0050999] comp128635_c0_seq2,915,42.5137,0.63105534,3,0,,4.00E-95,P19174,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0038095; GO:0038096; GO:0050852; GO:0000186; GO:0007202; GO:0007411; GO:0007596; GO:0005509; GO:0071364; GO:0019221; GO:0005829; GO:0007173; GO:0008543; GO:0001701; GO:0045087; GO:0043647; GO:0035556; GO:0030027; GO:0050900; GO:0019048; GO:0048011; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0045766; GO:0043536; GO:0005057; GO:0001726,COP9 signalosome; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell receptor signaling pathway; activation of MAPKK activity; activation of phospholipase C activity; axon guidance; blood coagulation; calcium ion binding; cellular response to epidermal growth factor stimulus; cytokine-mediated signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; in utero embryonic development; innate immune response; inositol phosphate metabolic process; intracellular signal transduction; lamellipodium; leukocyte migration; modulation by virus of host morphology or physiology; neurotrophin TRK receptor signaling pathway; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; receptor signaling protein activity; ruffle,PF00168;PF00388;PF00387;PF00017;PF00018;,4.00E-46,CHOYP_LOC100377901.1.1,,,,,,,PLCG1_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032] comp128635_c0_seq3,928,43.6422,0.59093869,6,14,,8.00E-102,P19174,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0038095; GO:0038096; GO:0050852; GO:0000186; GO:0007202; GO:0007411; GO:0007596; GO:0005509; GO:0071364; GO:0019221; GO:0005829; GO:0007173; GO:0008543; GO:0001701; GO:0045087; GO:0043647; GO:0035556; GO:0030027; GO:0050900; GO:0019048; GO:0048011; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0045766; GO:0043536; GO:0005057; GO:0001726,COP9 signalosome; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell receptor signaling pathway; activation of MAPKK activity; activation of phospholipase C activity; axon guidance; blood coagulation; calcium ion binding; cellular response to epidermal growth factor stimulus; cytokine-mediated signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; in utero embryonic development; innate immune response; inositol phosphate metabolic process; intracellular signal transduction; lamellipodium; leukocyte migration; modulation by virus of host morphology or physiology; neurotrophin TRK receptor signaling pathway; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; receptor signaling protein activity; ruffle,PF00168;PF00388;PF00387;PF00017;PF00018;,,,,,,,,,PLCG1_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032] comp128636_c0_seq4,695,37.6978,0.40708981,9,29,,3.00E-48,Q8NBJ9,SID1 transmembrane family member 2,SID1 transmembrane family member 2,GO:0051033; GO:0033227; GO:0016021; GO:0005765,RNA transmembrane transporter activity; dsRNA transport; integral to membrane; lysosomal membrane,PF13965;,,,,,,,,,SIDT2_HUMAN,Homo sapiens (Human),cell morphogenesis [GO:0000902]; dsRNA transport [GO:0033227]; glucose homeostasis [GO:0042593]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; response to glucose [GO:0009749]; type B pancreatic cell development [GO:0003323]; type B pancreatic cell proliferation [GO:0044342] comp128642_c0_seq1,772,38.9896,0.59596472,57,412,,,,,,,,,6.00E-37,CHOYP_NDUFS4.1.1,9.00E-39,ruditapes2_c4071,,,,,,, comp128642_c0_seq2,795,38.7421,0.5836038,881,843,,7.00E-56,P0CB96,"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (NADH-ubiquinone oxidoreductase 18 kDa subunit)","NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (NADH-ubiquinone oxidoreductase 18 kDa subunit)",GO:0007420; GO:0019933; GO:0045333; GO:0022900; GO:0005747; GO:0032981; GO:0016651; GO:0048146; GO:0072593; GO:0051591,"brain development; cAMP-mediated signaling; cellular respiration; electron transport chain; mitochondrial respiratory chain complex I; mitochondrial respiratory chain complex I assembly; oxidoreductase activity, acting on NAD(P)H; positive regulation of fibroblast proliferation; reactive oxygen species metabolic process; response to cAMP",PF04800;,7.00E-36,CHOYP_NEMVEDRAFT_V1G180651.1.2,1.00E-55,ruditapes2_c47,,,,,NDUS4_PONPY,Pongo pygmaeus (Bornean orangutan),brain development [GO:0007420]; cAMP-mediated signaling [GO:0019933]; cellular respiration [GO:0045333]; electron transport chain [GO:0022900]; mitochondrial respiratory chain complex I assembly [GO:0032981]; positive regulation of fibroblast proliferation [GO:0048146]; reactive oxygen species metabolic process [GO:0072593]; response to cAMP [GO:0051591] comp128644_c0_seq2,1048,43.1298,0.59772134,0,6,,2.00E-79,Q9NPB8,Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5),Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5),GO:0005829; GO:0006071; GO:0047389; GO:0008889; GO:0046474; GO:0044281; GO:2001070,cytosol; glycerol metabolic process; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; glycerophospholipid biosynthetic process; small molecule metabolic process; starch binding,PF00686;PF03009;,,,,,,,,,GPCP1_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]; skeletal muscle tissue development [GO:0007519] comp128644_c0_seq3,1011,43.1256,0.57717,5,1,,1.00E-28,Q02979,Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46),Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46),GO:0005737; GO:0006071; GO:0047389; GO:0008889; GO:0046475,cytoplasm; glycerol metabolic process; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; glycerophospholipid catabolic process,PF12796;PF03009;PF03105;,,,,,,,,,GDE1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475] comp128644_c0_seq4,582,42.7835,0.69230974,0,0,,4.00E-06,P37965,Glycerophosphoryl diester phosphodiesterase (Glycerophosphodiester phosphodiesterase) (EC 3.1.4.46),Glycerophosphoryl diester phosphodiesterase (Glycerophosphodiester phosphodiesterase) (EC 3.1.4.46),GO:0006071; GO:0008889; GO:0006629; GO:0046872,glycerol metabolic process; glycerophosphodiester phosphodiesterase activity; lipid metabolic process; metal ion binding,PF03009;,,,,,,,,,GLPQ_BACSU,Bacillus subtilis (strain 168),glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629] comp128645_c0_seq1,787,38.1194,0.45822225,57,67,,6.00E-53,Q32QL6,"Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)","Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)",GO:0004602; GO:0005739; GO:0007275; GO:0047066; GO:0006979,glutathione peroxidase activity; mitochondrion; multicellular organismal development; phospholipid-hydroperoxide glutathione peroxidase activity; response to oxidative stress,PF00255;,1.00E-39,CHOYP_GPX1.4.4,,,,,,,GPX4_CALJA,Callithrix jacchus (White-tufted-ear marmoset),multicellular organism development [GO:0007275]; response to oxidative stress [GO:0006979] comp128655_c0_seq1,1421,38.0014,0.53051663,160,794,,5.00E-70,Q5BK22,GTP-binding protein 8,GTP-binding protein 8,GO:0005525; GO:0000917; GO:0005739,GTP binding; barrier septum assembly; mitochondrion,PF01926;,,,,,,,,,GTPB8_RAT,Rattus norvegicus (Rat),barrier septum assembly [GO:0000917] comp128655_c0_seq2,638,40.1254,0.47289663,35,160,,3.00E-30,B3CL86,Probable GTP-binding protein EngB,Probable GTP-binding protein EngB,GO:0005525; GO:0000917,GTP binding; barrier septum assembly,PF01926;,,,,,,,,,ENGB_WOLPP,Wolbachia pipientis subsp. Culex pipiens (strain wPip),cell cycle [GO:0007049]; cell division [GO:0051301] comp128657_c0_seq1,798,45.2381,0.54172915,32,62,,5.00E-36,Q6PCD5,E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201),E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201),GO:0006281; GO:0016605; GO:0005737; GO:0031571; GO:0005634; GO:0010212; GO:0004842; GO:0008270,DNA repair; PML body; cytoplasm; mitotic G1 DNA damage checkpoint; nucleus; response to ionizing radiation; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,RFWD3_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mitotic G1 DNA damage checkpoint [GO:0031571]; positive regulation of defense response to virus by host [GO:0002230]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; xenophagy [GO:0098792] comp128660_c0_seq1,1300,37.3077,0.91031865,6,325,,1.00E-22,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp128664_c1_seq1,371,32.0755,0.63409552,9,44,,,,,,,,,9.00E-12,CHOYP_contig_054158,,,,,,,,, comp128670_c0_seq1,1309,40.6417,0.61155156,48,184,,2.00E-55,Q99LJ0,CTTNBP2 N-terminal-like protein,CTTNBP2 N-terminal-like protein,GO:0015629; GO:0005737,actin cytoskeleton; cytoplasm,PF09727;,6.00E-128,CHOYP_CTTB2.1.2,,,,,,,CT2NL_MOUSE,Mus musculus (Mouse),negative regulation of transmembrane transport [GO:0034763]; negative regulation of transporter activity [GO:0032410]; protein dephosphorylation [GO:0006470] comp128685_c0_seq1,1728,43.6921,0.40082205,0,0,,,,,,,,,0,CHOYP_BRAFLDRAFT_93002.1.1,,,,,,,,, comp128685_c0_seq2,2166,44.5983,0.33486582,0,0,,6.00E-18,Q5TZE1,BTB/POZ domain-containing protein 6-B,BTB/POZ domain-containing protein 6-B,GO:0030154; GO:0000932; GO:0007399,cell differentiation; cytoplasmic mRNA processing body; nervous system development,PF07707;PF00651;PF08005;,,,,,,,,,BTB6B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp128685_c0_seq3,2152,44.6561,0.3361029,0,5,,0,Q96Q07,BTB/POZ domain-containing protein 9,BTB/POZ domain-containing protein 9,GO:0008344; GO:0007155; GO:0042748; GO:0007616; GO:0060586; GO:1900242; GO:0050951; GO:0042428,"adult locomotory behavior; cell adhesion; circadian sleep/wake cycle, non-REM sleep; long-term memory; multicellular organismal iron ion homeostasis; regulation of synaptic vesicle endocytosis; sensory perception of temperature stimulus; serotonin metabolic process",PF07707;PF00651;PF00754;,0,CHOYP_BRAFLDRAFT_93002.1.1,,,,,,,BTBD9_HUMAN,Homo sapiens (Human),"adult locomotory behavior [GO:0008344]; circadian behavior [GO:0048512]; circadian sleep/wake cycle, non-REM sleep [GO:0042748]; long-term memory [GO:0007616]; modulation of synaptic transmission [GO:0050804]; multicellular organismal iron ion homeostasis [GO:0060586]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]; regulation of synaptic vesicle endocytosis [GO:1900242]; sensory perception of temperature stimulus [GO:0050951]; serotonin metabolic process [GO:0042428]" comp128687_c0_seq2,942,42.7813,0.54092739,41,125,,7.00E-89,D3ZYR1,FCH domain only protein 2,F-BAR domain only protein 2,GO:0048268; GO:0030136; GO:0072583; GO:0005905; GO:0010324; GO:0005546; GO:0001786; GO:0005886; GO:0072659,"clathrin coat assembly; clathrin-coated vesicle; clathrin-mediated endocytosis; coated pit; membrane invagination; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; plasma membrane; protein localization to plasma membrane",PF00611;PF10291;,5.00E-89,CHOYP_FCHO2.1.1,3.00E-153,ruditapes_c16036,,,,,FCHO2_RAT,Rattus norvegicus (Rat),clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659] comp128688_c0_seq1,230,40,0.5729275,147,97,,3.00E-07,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,,,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp128692_c0_seq1,1577,39.2517,0.5041643,58,69,,5.00E-154,Q28DH0,Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2),Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2),GO:0000287; GO:0009165; GO:0004749,magnesium ion binding; nucleotide biosynthetic process; ribose phosphate diphosphokinase activity,PF14572;PF13793;,2.00E-173,CHOYP_KPRB.1.1,,,,,,,KPRB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),nucleotide biosynthetic process [GO:0009165] comp128701_c0_seq2,1064,45.4887,0.49130374,0,0,,,,,,,,,4.00E-78,CHOYP_UBP25.1.1,,,,,,,,, comp128701_c0_seq3,1852,45.8963,0.45159088,19,45,,3.00E-119,Q9UHP3,Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25),Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25),GO:0032183; GO:0005737; GO:0005634; GO:0071108; GO:0070536; GO:0006508; GO:0004221; GO:0006511; GO:0004843,SUMO binding; cytoplasm; nucleus; protein K48-linked deubiquitination; protein K63-linked deubiquitination; proteolysis; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;PF02809;,,,,,,,,,UBP25_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; proteolysis [GO:0006508]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128702_c0_seq1,1156,37.6298,0.80166351,102,57,,3.00E-45,Q9CX98,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_MOUSE,Mus musculus (Mouse), comp128703_c0_seq1,1067,43.6739,0.70979238,19,35,,2.00E-62,Q8MQW8,Protein sprint (SH2 poly-proline-containing Ras-interactor protein),Protein sprint (SH2 poly-proline-containing Ras-interactor protein),GO:0005096; GO:0007298; GO:0005938; GO:0030139; GO:0006897; GO:0005085; GO:0007275; GO:0043547; GO:0007165,GTPase activator activity; border follicle cell migration; cell cortex; endocytic vesicle; endocytosis; guanyl-nucleotide exchange factor activity; multicellular organismal development; positive regulation of GTPase activity; signal transduction,PF00788;PF00017;PF02204;,,,,,,,,,SPRI_DROME,Drosophila melanogaster (Fruit fly),axon extension [GO:0048675]; border follicle cell migration [GO:0007298]; endocytosis [GO:0006897]; regulation of Rab protein signal transduction [GO:0032483]; signal transduction [GO:0007165] comp128703_c2_seq2,719,41.0292,0.46567585,25,58,,,,,,,,,8.00E-35,CHOYP_LOC657959.1.1,,,,,,,,, comp128705_c0_seq1,711,47.1167,0.68593585,9,138,,1.00E-34,Q13231,Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),GO:0008061; GO:0006032; GO:0008843; GO:0005615; GO:0006955; GO:0005764; GO:0000272; GO:0009617,chitin binding; chitin catabolic process; endochitinase activity; extracellular space; immune response; lysosome; polysaccharide catabolic process; response to bacterium,PF01607;PF00704;,,,,,,,,,CHIT1_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; response to bacterium [GO:0009617] comp128710_c1_seq2,969,43.9628,0.48582863,21,27,,1.00E-20,P51112,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0005737; GO:0005634; GO:0048513; GO:0008134,cytoplasm; nucleus; organ development; transcription factor binding,PF12372;,,,,,,,,,HD_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),animal organ development [GO:0048513] comp128712_c0_seq4,910,35.2747,0.50415113,0,0,,4.00E-13,Q5FWH2,Putative E3 ubiquitin-protein ligase UNKL (EC 6.3.2.-) (RING finger protein unkempt-like),Putative E3 ubiquitin-protein ligase UNKL (EC 6.3.2.-) (RING finger protein unkempt-like),GO:0005737; GO:0016874; GO:0005634; GO:0016567; GO:0008270,cytoplasm; ligase activity; nucleus; protein ubiquitination; zinc ion binding,PF00642;,,,,,,,,,UNKL_MOUSE,Mus musculus (Mouse), comp128712_c0_seq7,615,42.9268,0.63651144,21,10,,,,,,,,,1.00E-30,CHOYP_BRAFLDRAFT_64737.1.1,,,,,,,,, comp128712_c0_seq8,534,37.0787,0.71143867,0,0,,5.00E-09,Q86B79,RING finger protein unkempt,RING finger protein unkempt,GO:0003677; GO:0008407; GO:0048749; GO:0005737; GO:0007476; GO:0002164; GO:0008270,DNA binding; chaeta morphogenesis; compound eye development; cytoplasm; imaginal disc-derived wing morphogenesis; larval development; zinc ion binding,PF00642;,,,,,,,,,UNK_DROME,Drosophila melanogaster (Fruit fly),chaeta morphogenesis [GO:0008407]; compound eye development [GO:0048749]; imaginal disc-derived wing morphogenesis [GO:0007476]; larval development [GO:0002164]; neuron differentiation [GO:0030182]; regulation of neurogenesis [GO:0050767] comp128713_c0_seq1,1722,43.2056,0.84843071,17,18100,female>male,2.00E-23,P35555,Fibrillin-1,Fibrillin-1 [Cleaved into: Asprosin],GO:0005604; GO:0005509; GO:0030198; GO:0005201; GO:0005615; GO:0007507; GO:0001527; GO:0035582; GO:0035583; GO:0001501,basement membrane; calcium ion binding; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; heart development; microfibril; sequestering of BMP in extracellular matrix; sequestering of TGFbeta in extracellular matrix; skeletal system development,PF12662;PF07645;PF00683;,,,,,,,,,FBN1_HUMAN,Homo sapiens (Human),activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] comp128720_c2_seq1,1964,42.5153,0.53539144,24,0,,3.00E-18,Q8C753,Uncharacterized protein KIAA0556,Protein KIAA0556,GO:0005634; GO:0005886,nucleus; plasma membrane,PF14652;,,,,,,,,,K0556_MOUSE,Mus musculus (Mouse), comp128720_c2_seq2,1797,41.6806,0.557781,0,0,,4.00E-29,Q5XK85,Uncharacterized protein KIAA0556 homolog,Protein KIAA0556 homolog,,,PF14652;,2.00E-15,CHOYP_LOC100691694.1.1,7.00E-19,ruditapes_c34409,,,,,K0556_XENLA,Xenopus laevis (African clawed frog), comp128724_c0_seq1,927,38.1877,0.41769596,5050,13673,,6.00E-25,Q3SZV5,Proteasome maturation protein (Proteassemblin),Proteasome maturation protein (Proteassemblin),GO:0005829; GO:0005783; GO:0005634; GO:0031090; GO:0043248; GO:0000502,cytosol; endoplasmic reticulum; nucleus; organelle membrane; proteasome assembly; proteasome complex,,3.00E-22,CHOYP_POMP.1.2,1.00E-69,ruditapes_lrc32326,,,,,POMP_BOVIN,Bos taurus (Bovine),proteasome assembly [GO:0043248] comp128726_c0_seq3,2500,43.72,0.44457606,14,444,,7.00E-41,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,5.00E-120,CHOYP_PHUM_PHUM289860.1.1,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp128731_c0_seq1,781,46.991,0.59388744,48,76,,6.00E-36,Q3T062,RRP15-like protein (Ribosomal RNA-processing protein 15),RRP15-like protein (Ribosomal RNA-processing protein 15),,,PF07890;,2.00E-16,CHOYP_LOC100549868.1.1,,,,,,,RRP15_BOVIN,Bos taurus (Bovine),maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] comp128734_c1_seq3,635,39.0551,0.58552128,48,48,,1.00E-33,Q6PG95,Protein cramped-like (Hematological and neurological expressed 1-like protein),Protein cramped-like (Cramped chromatin regulator homolog 1) (Hematological and neurological expressed 1-like protein),GO:0003677; GO:0003682; GO:0005634,DNA binding; chromatin binding; nucleus,,,,,,,,,,CRML_MOUSE,Mus musculus (Mouse), comp128736_c0_seq1,2363,40.9649,0.44622917,33239,83405,,1.00E-123,Q64737,Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)],Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)],GO:0006189; GO:0005524; GO:0005737; GO:0046872; GO:0032259; GO:0008168; GO:0004637; GO:0004641; GO:0004644; GO:0009113,'de novo' IMP biosynthetic process; ATP binding; cytoplasm; metal ion binding; methylation; methyltransferase activity; phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity; phosphoribosylglycinamide formyltransferase activity; purine nucleobase biosynthetic process,PF00586;PF02769;PF00551;PF01071;PF02843;PF02844;,3.00E-77,CHOYP_RPS24.5.8,6.00E-104,ruditapes2_lrc2615,,,,,PUR2_MOUSE,Mus musculus (Mouse),'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654] comp128739_c0_seq1,1631,46.2906,0.74807509,82,90,,5.00E-155,Q96RV3,Pecanex-like protein 1 (Pecanex homolog),Pecanex-like protein 1 (Pecanex homolog protein 1),GO:0016021,integral to membrane,PF05041;,1.00E-113,CHOYP_PCX1.1.1,,,,,,,PCX1_HUMAN,Homo sapiens (Human), comp128740_c0_seq1,1794,32.6644,0.48599763,1045,4979,,2.00E-23,Q9CR80,Protein FAM32A (Ovarian tumor associated gene 12) (OTAG-12),Protein FAM32A (Ovarian tumor associated gene 12) (OTAG-12),GO:0006915; GO:0007049; GO:0005730,apoptotic process; cell cycle; nucleolus,PF08555;,2.00E-22,CHOYP_PCSK4.2.2,3.00E-30,ruditapes_c28131,,,,,FA32A_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell cycle [GO:0007049] comp128741_c0_seq1,5660,34.258,0.75015731,352284,13836,,3.00E-118,Q9MFN9,Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),GO:0009055; GO:0016021; GO:0046872; GO:0005743; GO:0016491; GO:0070469; GO:0022904,electron carrier activity; integral to membrane; metal ion binding; mitochondrial inner membrane; oxidoreductase activity; respiratory chain; respiratory electron transport chain,PF00032;PF00033;,,,3.00E-48,ruditapes2_c29,,,,,CYB_COLHO,Cochliomyia hominivorax (Primary screw-worm) (Lucilia hominivorax),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp128743_c1_seq1,1329,46.3506,0.4642482,55,108,,3.00E-23,Q9PU47,PDZ and LIM domain protein 3 (Alpha-actinin-associated LIM protein),PDZ and LIM domain protein 3 (Alpha-actinin-associated LIM protein),GO:0030018; GO:0005856; GO:0030027; GO:0008270,Z disc; cytoskeleton; lamellipodium; zinc ion binding,PF15936;PF00412;PF00595;,8.00E-19,CHOYP_LOC100162539.1.1,,,,,,,PDLI3_CHICK,Gallus gallus (Chicken), comp128744_c0_seq1,1371,43.4719,0.6344512,9,17,,2.00E-146,P50607,Tubby protein homolog,Tubby protein homolog,GO:0008020; GO:0005737; GO:0005829; GO:0005576; GO:0044259; GO:0005634; GO:0006909; GO:0007602; GO:0005886; GO:0050766; GO:0009725; GO:0060041; GO:0007605,G-protein coupled photoreceptor activity; cytoplasm; cytosol; extracellular region; multicellular organismal macromolecule metabolic process; nucleus; phagocytosis; phototransduction; plasma membrane; positive regulation of phagocytosis; response to hormone stimulus; retina development in camera-type eye; sensory perception of sound,PF01167;PF16322;,,,,,,,,,TUB_HUMAN,Homo sapiens (Human),"phagocytosis, recognition [GO:0006910]; photoreceptor cell maintenance [GO:0045494]; positive regulation of phagocytosis [GO:0050766]; protein localization to photoreceptor outer segment [GO:1903546]; receptor localization to nonmotile primary cilium [GO:0097500]; response to hormone [GO:0009725]; retina development in camera-type eye [GO:0060041]; sensory perception of sound [GO:0007605]" comp128744_c0_seq2,1811,43.4014,0.69211338,65,21,,,,,,,,,7.00E-148,CHOYP_LOC101063890.1.1,,,,,,,,, comp128748_c0_seq1,941,42.4017,0.83114947,3,16,,5.00E-58,Q92485,Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),GO:0005615; GO:0016798; GO:0006685; GO:0004767,"extracellular space; hydrolase activity, acting on glycosyl bonds; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity",PF00149;,,,,,,,,,ASM3B_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] comp128748_c0_seq2,925,42.2703,0.85043395,7,0,,9.00E-06,Q9SB68,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase),Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase),GO:0047631; GO:0047734; GO:0046872,ADP-ribose diphosphatase activity; CDP-glycerol diphosphatase activity; metal ion binding,PF00149;,,,1.00E-30,ruditapes2_c2218,,,,,ADPRM_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp128750_c1_seq1,285,43.8596,0.36629549,4,28,,3.00E-07,Q09621,Beta-lactamase domain-containing protein 2,Beta-lactamase domain-containing protein 2,GO:0016021,integral to membrane,PF00144;,,,,,,,,,LACT2_CAEEL,Caenorhabditis elegans, comp128754_c0_seq3,751,43.9414,0.81067762,0,0,,2.00E-21,Q92045,"Cholesterol side-chain cleavage enzyme, mitochondrial (EC 1.14.15.6) (CYPXIA1) (Cholesterol desmolase) (Cytochrome P450 11A1) (Cytochrome P450(scc)) (Fragment)","Cholesterol side-chain cleavage enzyme, mitochondrial (EC 1.14.15.6) (CYPXIA1) (Cholesterol desmolase) (Cytochrome P450 11A1) (Cytochrome P450(scc)) (Fragment)",GO:0008207; GO:0008203; GO:0008386; GO:0020037; GO:0005506; GO:0031966; GO:0006694,C21-steroid hormone metabolic process; cholesterol metabolic process; cholesterol monooxygenase (side-chain-cleaving) activity; heme binding; iron ion binding; mitochondrial membrane; steroid biosynthetic process,PF00067;,,,,,,,,,CP11A_DASAM,Dasyatis americana (Southern stingray),C21-steroid hormone biosynthetic process [GO:0006700]; cholesterol metabolic process [GO:0008203] comp128759_c0_seq1,758,32.9815,0.88250267,233,4,,,,,,,,,,,3.00E-13,ruditapes_c21135,,,,,,, comp128760_c0_seq1,2262,36.6932,0.43767921,0,0,,5.00E-24,P51945,Cyclin-G1 (Cyclin-G),Cyclin-G1 (Cyclin-G),GO:0007420; GO:0051301; GO:0016049; GO:0030425; GO:0007067; GO:0007095; GO:0043066; GO:0043025; GO:0005634; GO:0048471; GO:0010243; GO:0006949,brain development; cell division; cell growth; dendrite; mitosis; mitotic G2 DNA damage checkpoint; negative regulation of apoptotic process; neuronal cell body; nucleus; perinuclear region of cytoplasm; response to organonitrogen compound; syncytium formation,PF00134;,,,,,,,,,CCNG1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of cell cycle [GO:0051726] comp128760_c0_seq4,1943,37.931,0.44593106,0,0,,3.00E-24,P51945,Cyclin-G1 (Cyclin-G),Cyclin-G1 (Cyclin-G),GO:0007420; GO:0051301; GO:0016049; GO:0030425; GO:0007067; GO:0007095; GO:0043066; GO:0043025; GO:0005634; GO:0048471; GO:0010243; GO:0006949,brain development; cell division; cell growth; dendrite; mitosis; mitotic G2 DNA damage checkpoint; negative regulation of apoptotic process; neuronal cell body; nucleus; perinuclear region of cytoplasm; response to organonitrogen compound; syncytium formation,PF00134;,,,,,,,,,CCNG1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of cell cycle [GO:0051726] comp128761_c0_seq1,1014,47.2387,0.976338,88,2602,,1.00E-07,P35440,Thrombospondin-2,Thrombospondin-2,GO:0005604; GO:0005509; GO:0007155; GO:0008201; GO:0016525,basement membrane; calcium ion binding; cell adhesion; heparin binding; negative regulation of angiogenesis,PF12947;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525] comp128763_c0_seq4,1312,39.4817,0.43170159,26,59,,6.00E-39,Q9WUU9,Germinal-center associated nuclear protein (GANP) (GC-associated DNA primase),Germinal-center associated nuclear protein (GANP) (GC-associated DNA primase),GO:0005737; GO:0005829; GO:0005634,cytoplasm; cytosol; nucleus,PF16766;PF16769;PF16768;PF03399;,,,,,,,,,MCM3A_MOUSE,Mus musculus (Mouse),immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein transport [GO:0015031] comp128765_c0_seq1,3918,41.0669,0.41386275,4705,13261,,0,Q5R9I6,26S proteasome non-ATPase regulatory subunit 2,26S proteasome non-ATPase regulatory subunit 2,GO:0030234; GO:0022624; GO:0050790; GO:0042176,enzyme regulator activity; proteasome accessory complex; regulation of catalytic activity; regulation of protein catabolic process,PF01851;,0,CHOYP_PSMD2.1.3,0,ruditapes_c14905,,,,,PSMD2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),regulation of protein catabolic process [GO:0042176] comp128769_c1_seq1,1204,40.4485,0.55689676,37,110,,3.00E-13,Q6PF15,Kelch-like protein 35,Kelch-like protein 35,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH35_HUMAN,Homo sapiens (Human), comp128770_c0_seq3,1805,36.3989,0.90465882,1838,107,,1.00E-40,P15512,Histone H3.3 (H3.2) (Minor histone H3 variant) (hv2),Histone H3.3 (H3.2) (Minor histone H3 variant) (hv2),GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;,5.00E-11,CHOYP_LOC100902368.1.1,,,,,,,H33_TETPY,Tetrahymena pyriformis, comp128773_c1_seq3,209,40.1914,0.71430207,66,80,,,,,,,,,,,4.00E-11,ruditapes_c14002,,,,,,, comp128781_c0_seq3,889,42.6322,0.49609873,16,90,,7.00E-106,Q6UPE0,"Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)","Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)",GO:0008812; GO:0050660; GO:0019285; GO:0005743,choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline; mitochondrial inner membrane,PF05199;PF00732;,5.00E-64,CHOYP_LOC100366344.1.1,,,,,,,CHDH_RAT,Rattus norvegicus (Rat),glycine betaine biosynthetic process from choline [GO:0019285] comp128782_c0_seq1,1370,36.7883,0.8532791,28,438,,1.00E-62,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,3.00E-25,CHOYP_CPIPJ_CPIJ007618.1.1,6.00E-12,ruditapes_c10345,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp128783_c0_seq1,358,48.6034,0.14246143,25,0,,,,,,,,,,,6.00E-37,ruditapes_c26405,,,,,,, comp128783_c1_seq1,852,47.3005,0.56979297,34,14,,7.00E-61,Q6ZPS6,Ankyrin repeat and IBR domain-containing protein 1,Ankyrin repeat and IBR domain-containing protein 1,GO:0008270,zinc ion binding,PF00023;PF01485;,3.00E-72,CHOYP_LOC100368072.1.1,,,,,,,AKIB1_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp128783_c1_seq2,416,42.3077,0.54022854,0,0,,3.00E-17,Q9P2G1,Ankyrin repeat and IBR domain-containing protein 1,Ankyrin repeat and IBR domain-containing protein 1,GO:0008270,zinc ion binding,PF00023;PF01485;,,,,,,,,,AKIB1_HUMAN,Homo sapiens (Human),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp128784_c0_seq1,1654,40.7497,0.6804128,52,414,,2.00E-143,Q27968,"DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)","DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)",GO:0005783; GO:0006986,endoplasmic reticulum; response to unfolded protein,PF00226;PF09976;PF13181;,3.00E-50,CHOYP_DNJC3.1.1,,,,,,,DNJC3_BOVIN,Bos taurus (Bovine),cellular response to cold [GO:0070417]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of translation initiation in response to endoplasmic reticulum stress [GO:0036494]; response to unfolded protein [GO:0006986] comp128786_c0_seq2,668,41.4671,0.43984319,8,162,,,,,,,,,1.00E-12,CHOYP_BRAFLDRAFT_80934.1.2,4.00E-30,ruditapes_c12158,,,,,,, comp128788_c0_seq2,954,35.6394,0.69416157,598,1827,,1.00E-51,P55770,"NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]","NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]",GO:0003723; GO:0008380; GO:0006397; GO:0005730; GO:0042254; GO:0005681,RNA binding; RNA splicing; mRNA processing; nucleolus; ribosome biogenesis; spliceosomal complex,PF01248;,3.00E-73,CHOYP_LOC100371232.1.1,2.00E-72,ruditapes_c12660,,,,,NH2L1_RAT,Rattus norvegicus (Rat),"maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]" comp128790_c2_seq2,863,40.7879,0.39853765,9,32,,3.00E-14,Q68D06,Schlafen family member 13,Schlafen family member 13,GO:0005524; GO:0005622,ATP binding; intracellular,PF04326;PF09848;,,,,,,,,,SLN13_HUMAN,Homo sapiens (Human), comp128792_c0_seq1,285,41.0526,0.59021953,10,23,,2.00E-30,Q91YI1,Autophagy-related protein 13,Autophagy-related protein 13,GO:0070969; GO:0000045; GO:0005829; GO:0000407,ULK1-ATG13-FIP200 complex; autophagic vacuole assembly; cytosol; pre-autophagosomal structure,PF10033;,5.00E-20,CHOYP_ATG13.1.1,,,,,,,ATG13_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp128792_c1_seq1,1152,45.3993,0.42178844,72,80,,7.00E-21,Q9VHR6,Autophagy-related protein 13 homolog,Autophagy-related protein 13 homolog,GO:0034273; GO:0006914; GO:0005829; GO:0000407; GO:0010506,Atg1p signaling complex; autophagy; cytosol; pre-autophagosomal structure; regulation of autophagy,PF10033;,,,,,,,,,ATG13_DROME,Drosophila melanogaster (Fruit fly),activation of protein kinase activity [GO:0032147]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; larval midgut cell programmed cell death [GO:0035096]; positive regulation of nurse cell apoptotic process [GO:0045850]; regulation of autophagy [GO:0010506] comp128795_c0_seq1,2611,44.1593,0.44379186,0,0,,0,Q8HXQ5,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,3.00E-103,CHOYP_MRP1.7.10,,,,,,,MRP1_BOVIN,Bos taurus (Bovine), comp128795_c0_seq10,2926,44.0191,0.38243668,0,0,,0,Q8HXQ5,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_BOVIN,Bos taurus (Bovine), comp128795_c0_seq12,1691,44.8255,0.51476984,0,0,,4.00E-80,Q96J65,Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005739,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrion",PF00664;PF00005;,1.00E-29,CHOYP_MRP1.6.10,,,,,,,MRP9_HUMAN,Homo sapiens (Human), comp128795_c0_seq14,2006,44.5165,0.41508788,0,0,,3.00E-79,Q96J65,Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005739,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrion",PF00664;PF00005;,2.00E-29,CHOYP_MRP1.10.10,,,,,,,MRP9_HUMAN,Homo sapiens (Human), comp128795_c0_seq15,2707,43.9232,0.42447566,0,0,,0,Q8VI47,Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2),Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2),GO:0005524; GO:0006200; GO:0042626; GO:0016324; GO:0005887; GO:0046581,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; apical plasma membrane; integral to plasma membrane; intercellular canaliculus",PF00664;PF00005;,4.00E-103,CHOYP_MRP1.7.10,,,,,,,MRP2_MOUSE,Mus musculus (Mouse),cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327] comp128795_c0_seq18,2748,43.9229,0.38651068,0,0,,4.00E-171,Q54P13,ABC transporter C family member 8 (ABC transporter ABCC.8),ABC transporter C family member 8 (ABC transporter ABCC.8),GO:0005524; GO:0042626; GO:0031154; GO:0016021; GO:0031288,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; culmination involved in sorocarp development; integral to membrane; sorocarp morphogenesis",PF00664;PF00005;PF16185;,,,,,,,,,ABCC8_DICDI,Dictyostelium discoideum (Slime mold),culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810] comp128795_c0_seq19,2508,44.0191,0.44063058,0,0,,0,Q5F364,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,1.00E-33,CHOYP_MRP1.6.10,,,,,,,MRP1_CHICK,Gallus gallus (Chicken), comp128795_c0_seq2,1881,44.9229,0.39151909,0,0,,5.00E-68,Q96J65,Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005739,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrion",PF00664;PF00005;,,,,,,,,,MRP9_HUMAN,Homo sapiens (Human), comp128795_c0_seq20,1607,45.3018,0.42729608,0,0,,5.00E-60,Q09429,ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1),ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1),GO:0005524; GO:0006200; GO:0008282; GO:0042626; GO:0046676; GO:0043268; GO:0005267; GO:0042493; GO:0032868; GO:0032496; GO:0009268; GO:0010043; GO:0042383; GO:0008281; GO:0030672; GO:0019905,"ATP binding; ATP catabolic process; ATP-sensitive potassium channel complex; ATPase activity, coupled to transmembrane movement of substances; negative regulation of insulin secretion; positive regulation of potassium ion transport; potassium channel activity; response to drug; response to insulin stimulus; response to lipopolysaccharide; response to pH; response to zinc ion; sarcolemma; sulfonylurea receptor activity; synaptic vesicle membrane; syntaxin binding",PF00664;PF00005;,1.00E-29,CHOYP_MRP1.10.10,,,,,,,ABCC8_RAT,Rattus norvegicus (Rat),cellular response to organic substance [GO:0071310]; negative regulation of insulin secretion [GO:0046676]; positive regulation of potassium ion transport [GO:0043268]; response to drug [GO:0042493]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; response to zinc ion [GO:0010043] comp128795_c0_seq21,1732,44.8037,0.45285044,0,0,,3.00E-26,Q6FIK3,"Iron-sulfur clusters transporter ATM1, mitochondrial","Iron-sulfur clusters transporter ATM1, mitochondrial",GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0006811; GO:0055072; GO:0005743,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; ion transport; iron ion homeostasis; mitochondrial inner membrane",PF00664;PF00005;,,,,,,,,,ATM1_CANGA,Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata),cellular iron ion homeostasis [GO:0006879]; ion transport [GO:0006811] comp128795_c0_seq22,2549,44.0173,0.39925619,0,0,,0,Q5F364,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_CHICK,Gallus gallus (Chicken), comp128795_c0_seq23,2474,44.0582,0.41062293,0,0,,5.00E-172,Q54P13,ABC transporter C family member 8 (ABC transporter ABCC.8),ABC transporter C family member 8 (ABC transporter ABCC.8),GO:0005524; GO:0042626; GO:0031154; GO:0016021; GO:0031288,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; culmination involved in sorocarp development; integral to membrane; sorocarp morphogenesis",PF00664;PF00005;PF16185;,3.00E-103,CHOYP_MRP1.7.10,,,,,,,ABCC8_DICDI,Dictyostelium discoideum (Slime mold),culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810] comp128795_c0_seq24,1566,45.3384,0.49116355,0,0,,1.00E-68,Q96J65,Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005739,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrion",PF00664;PF00005;,1.00E-29,CHOYP_MRP1.6.10,,,,,,,MRP9_HUMAN,Homo sapiens (Human), comp128795_c0_seq27,1840,44.9457,0.44511619,0,0,,3.00E-68,Q96J65,Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005739,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrion",PF00664;PF00005;,2.00E-29,CHOYP_MRP1.10.10,,,,,,,MRP9_HUMAN,Homo sapiens (Human), comp128795_c0_seq28,2652,44.1554,0.40436152,0,0,,0,Q8HXQ5,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_BOVIN,Bos taurus (Bovine), comp128795_c0_seq3,2823,43.8895,0.37680921,0,0,,0,O15438,Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3),Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3),GO:0005524; GO:0042626; GO:0015721; GO:0008206; GO:0005887; GO:0008514,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; bile acid and bile salt transport; bile acid metabolic process; integral to plasma membrane; organic anion transmembrane transporter activity",PF00664;PF00005;,,,,,,,,,MRP3_HUMAN,Homo sapiens (Human),bile acid and bile salt transport [GO:0015721]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp128795_c0_seq4,2433,44.0608,0.45345489,0,0,,3.00E-172,Q54P13,ABC transporter C family member 8 (ABC transporter ABCC.8),ABC transporter C family member 8 (ABC transporter ABCC.8),GO:0005524; GO:0042626; GO:0031154; GO:0016021; GO:0031288,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; culmination involved in sorocarp development; integral to membrane; sorocarp morphogenesis",PF00664;PF00005;PF16185;,3.00E-103,CHOYP_MRP1.7.10,,,,,,,ABCC8_DICDI,Dictyostelium discoideum (Slime mold),culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810] comp128795_c0_seq6,2782,43.8893,0.4136244,0,0,,0,Q8HXQ5,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_BOVIN,Bos taurus (Bovine), comp128795_c0_seq7,1965,44.5293,0.46726467,0,0,,9.00E-72,Q96J66,ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8),ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0055085,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; transmembrane transport",PF00664;PF00005;,2.00E-29,CHOYP_MRP1.10.10,,,,,,,ABCCB_HUMAN,Homo sapiens (Human),organic anion transport [GO:0015711]; purine nucleotide transport [GO:0015865]; transmembrane transport [GO:0055085] comp128795_c0_seq8,2885,44.0208,0.41771295,0,0,,0,Q8VI47,Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2),Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2),GO:0005524; GO:0006200; GO:0042626; GO:0016324; GO:0005887; GO:0046581,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; apical plasma membrane; integral to plasma membrane; intercellular canaliculus",PF00664;PF00005;,,,,,,,,,MRP2_MOUSE,Mus musculus (Mouse),cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327] comp128802_c0_seq3,1823,40.2084,0.48410595,0,0,,2.00E-144,Q13905,Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G),Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G),GO:0017034; GO:0032486; GO:0000186; GO:0001568; GO:0016337; GO:0071320; GO:0005829; GO:0005769; GO:0061028; GO:0038180; GO:0048011; GO:0048008; GO:0032854; GO:0010976; GO:1901888,Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; activation of MAPKK activity; blood vessel development; cell-cell adhesion; cellular response to cAMP; cytosol; early endosome; establishment of endothelial barrier; nerve growth factor signaling pathway; neurotrophin TRK receptor signaling pathway; platelet-derived growth factor receptor signaling pathway; positive regulation of Rap GTPase activity; positive regulation of neuron projection development; regulation of cell junction assembly,PF00617;PF00618;,,,,,,,,,RPGF1_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; blood vessel development [GO:0001568]; cellular response to cAMP [GO:0071320]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of Ras protein signal transduction [GO:0046580]; nerve growth factor signaling pathway [GO:0038180]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp128802_c0_seq4,1763,40.4991,0.49297365,0,0,,5.00E-25,Q55GH9,Ras guanine nucleotide exchange factor W (RasGEF domain-containing protein W),Ras guanine nucleotide exchange factor W (RasGEF domain-containing protein W),GO:0005085; GO:0016021; GO:0005622; GO:0051056; GO:0007264,guanyl-nucleotide exchange factor activity; integral to membrane; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00617;PF00618;,7.00E-97,CHOYP_LOC662211.1.1,,,,,,,GEFW_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp128803_c0_seq1,333,37.2372,0.17542175,4,19,,,,,,,,,,,2.00E-11,ruditapes_c31683,,,,,,, comp128803_c4_seq1,1008,47.9167,0.43386696,0,0,,1.00E-13,B4M140,Lateral signaling target protein 2 homolog,Lateral signaling target protein 2 homolog,GO:0046872,metal ion binding,PF01363;,,,,,,,,,LST2_DROVI,Drosophila virilis (Fruit fly), comp128803_c4_seq5,1152,48.3507,0.44648423,0,0,,3.00E-40,O95405,Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation),Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation),GO:0005545; GO:0007183; GO:0007184; GO:0031901; GO:0006897; GO:0046872; GO:0030512; GO:0008236; GO:0007179,1-phosphatidylinositol binding; SMAD protein complex assembly; SMAD protein import into nucleus; early endosome membrane; endocytosis; metal ion binding; negative regulation of transforming growth factor beta receptor signaling pathway; serine-type peptidase activity; transforming growth factor beta receptor signaling pathway,PF11979;PF01363;PF11409;,7.00E-19,CHOYP_LOC575625.2.2,,,,,,,ZFYV9_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; SMAD protein complex assembly [GO:0007183]; SMAD protein import into nucleus [GO:0007184]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp128806_c0_seq1,1425,44.4211,0.36095435,645,3171,,7.00E-159,B7PY76,Ribosome biogenesis protein WDR12 homolog,Ribosome biogenesis protein WDR12 homolog,GO:0005730; GO:0005654; GO:0006364,nucleolus; nucleoplasm; rRNA processing,PF08154;PF00400;,2.00E-103,CHOYP_WDR12.1.1,,,,,,,WDR12_IXOSC,Ixodes scapularis (Black-legged tick) (Deer tick),"maturation of 5.8S rRNA [GO:0000460]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA [GO:0000470]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]" comp128808_c0_seq1,1094,36.7459,0.90047029,103,64,,1.00E-24,P51152,Ras-related protein Rab-12 (Fragment),Ras-related protein Rab-12 (Fragment),GO:0019003; GO:0005525; GO:0000139; GO:0044257; GO:0008333; GO:0005765; GO:0005764; GO:0015031; GO:0055038; GO:0007264,GDP binding; GTP binding; Golgi membrane; cellular protein catabolic process; endosome to lysosome transport; lysosomal membrane; lysosome; protein transport; recycling endosome membrane; small GTPase mediated signal transduction,PF00071;,3.00E-80,CHOYP_DVIR_GJ12112.3.3,,,,,,,RAB12_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),autophagy [GO:0006914]; cellular protein catabolic process [GO:0044257]; endosome to lysosome transport [GO:0008333]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp128811_c0_seq2,1110,44.3243,0.56085663,10,22,,7.00E-25,Q15643,Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230),Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230),GO:0005794; GO:0005856; GO:0016020; GO:0005634; GO:0000042; GO:0003713; GO:0006366; GO:0003281,Golgi apparatus; cytoskeleton; membrane; nucleus; protein targeting to Golgi; transcription coactivator activity; transcription from RNA polymerase II promoter; ventricular septum development,,,,2.00E-48,ruditapes_c6924,,,,,TRIPB_HUMAN,Homo sapiens (Human),protein targeting to Golgi [GO:0000042]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281] comp128813_c0_seq1,883,39.1846,0.59104813,7327,10946,,2.00E-08,Q8WYQ3,"Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (Protein N27C7-4)","Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (Protein N27C7-4)",GO:0006754; GO:0005739; GO:2000984; GO:0006119,ATP biosynthetic process; mitochondrion; negative regulation of ATP citrate synthase activity; oxidative phosphorylation,PF06747;,1.00E-20,CHOYP_RL39.1.2,3.00E-13,ruditapes2_c2139,,,,,CHC10_HUMAN,Homo sapiens (Human),ATP biosynthetic process [GO:0006754]; mitochondrion organization [GO:0007005]; negative regulation of ATP citrate synthase activity [GO:2000984]; oxidative phosphorylation [GO:0006119] comp128815_c0_seq1,961,42.5598,0.56463744,231,1619,,5.00E-88,Q5TJF5,Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239),Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239),GO:0004303; GO:0006703; GO:0006633; GO:0005759; GO:0047035,estradiol 17-beta-dehydrogenase activity; estrogen biosynthetic process; fatty acid biosynthetic process; mitochondrial matrix; testosterone dehydrogenase (NAD+) activity,,2.00E-31,CHOYP_BRAFLDRAFT_281754.1.1,6.00E-80,ruditapes_c3359,,,,,DHB8_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633] comp128826_c0_seq4,599,40.7346,0.282183,0,34,,2.00E-18,Q9NQG7,Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog),Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog),GO:0007596; GO:0007599; GO:0005764; GO:0007040; GO:0030318; GO:0042470; GO:0016020; GO:0042827; GO:0048075; GO:0050821; GO:0006605,blood coagulation; hemostasis; lysosome; lysosome organization; melanocyte differentiation; melanosome; membrane; platelet dense granule; positive regulation of eye pigmentation; protein stabilization; protein targeting,,,,,,,,,,HPS4_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; hemostasis [GO:0007599]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605] comp128830_c0_seq2,1022,40.1174,0.5600948,17,45,,7.00E-21,O54926,Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP),Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP),GO:0006915; GO:0005737; GO:0046872; GO:0005634; GO:0001618,apoptotic process; cytoplasm; metal ion binding; nucleus; virus receptor activity,PF05458;,,,,,,,,,SIVA_MOUSE,Mus musculus (Mouse),activation-induced cell death of T cells [GO:0006924]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030] comp128833_c0_seq1,1136,42.4296,0.29449878,6,154,,1.00E-24,Q9USQ7,Diphthine--ammonia ligase (EC 6.3.1.14) (Diphthamide synthase) (Diphthamide synthetase),Diphthine--ammonia ligase (EC 6.3.1.14) (Diphthamide synthase) (Diphthamide synthetase),GO:0005524; GO:0005829; GO:0017178; GO:0007126; GO:0005634; GO:0017183,ATP binding; cytosol; diphthine-ammonia ligase activity; meiosis; nucleus; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01902;PF01042;,7.00E-32,CHOYP_LOC100744165.1.1,,,,,,,MUG71_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),meiotic cell cycle [GO:0051321]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; regulation of cytoplasmic translation [GO:2000765] comp128837_c0_seq1,1491,42.0523,0.64896467,60,171,,0,Q9VFP2,Protein roadkill (Hh-induced MATH and BTB domain-containing protein),Protein roadkill (Hh-induced MATH and BTB domain-containing protein),GO:0042067; GO:0046331; GO:0042308; GO:0045879; GO:0005634; GO:0046330; GO:0043065; GO:0031648; GO:0042803; GO:0016567; GO:0030162; GO:0007367,establishment of ommatidial planar polarity; lateral inhibition; negative regulation of protein import into nucleus; negative regulation of smoothened signaling pathway; nucleus; positive regulation of JNK cascade; positive regulation of apoptotic process; protein destabilization; protein homodimerization activity; protein ubiquitination; regulation of proteolysis; segment polarity determination,PF00651;PF00917;,0,CHOYP_RDX.1.1,,,,,,,RDX_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; establishment of ommatidial planar polarity [GO:0042067]; eye development [GO:0001654]; eye morphogenesis [GO:0048592]; lateral inhibition [GO:0046331]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of proteolysis [GO:0030162]; segment polarity determination [GO:0007367] comp128838_c0_seq2,768,39.1927,0.80213288,38,42,,1.00E-06,O15016,Tripartite motif-containing protein 66,Tripartite motif-containing protein 66,GO:0016235; GO:0005634; GO:0008270,aggresome; nucleus; zinc ion binding,PF00439;PF00628;PF00643;,,,,,,,,,TRI66_HUMAN,Homo sapiens (Human), comp128841_c0_seq1,1040,44.9038,0.93556816,9,69,,2.00E-60,P50429,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0007417; GO:0005764; GO:0046872; GO:0005739; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; central nervous system development; lysosome; metal ion binding; mitochondrion; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,,,,,,,,,ARSB_MOUSE,Mus musculus (Mouse),colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632] comp128847_c0_seq1,833,44.1777,0.62248186,53,55,,6.00E-45,E2RK09,Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37),Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37),GO:0000082; GO:0051301; GO:0004197; GO:0007067; GO:0035871; GO:0071108; GO:0004221; GO:0006511; GO:0004843,G1/S transition of mitotic cell cycle; cell division; cysteine-type endopeptidase activity; mitosis; protein K11-linked deubiquitination; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;PF16674;PF02809;,,,,,,,,,UBP37_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128848_c0_seq1,558,42.1147,1.18035911,0,0,,,,,,,,,3.00E-45,CHOYP_C2H19ORF6.2.3,,,,,,,,, comp128848_c0_seq2,722,43.3518,1.15751454,0,0,,,,,,,,,4.00E-45,CHOYP_LOC100162380.1.1,,,,,,,,, comp128848_c0_seq6,558,41.7563,1.19709438,0,0,,,,,,,,,9.00E-27,CHOYP_C2H19ORF6.3.3,,,,,,,,, comp128849_c1_seq1,825,42.7879,0.45157,57,133,,5.00E-54,Q4V8K5,BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein),BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein),GO:0016020,membrane,PF03097;,2.00E-42,CHOYP_BRAFLDRAFT_115208.1.1,,,,,,,BROX_RAT,Rattus norvegicus (Rat), comp128850_c0_seq1,945,39.2593,0.46802773,12,0,,9.00E-52,Q0V8M0,Protein KRI1 homolog,Protein KRI1 homolog,,,PF05178;PF12936;,4.00E-21,CHOYP_LOC100489126.1.1,,,,,,,KRI1_BOVIN,Bos taurus (Bovine), comp128850_c0_seq2,850,39.6471,0.42029539,0,0,,2.00E-06,Q09799,Protein kri1,Protein kri1,GO:0044732; GO:0005730; GO:0005634; GO:0006364,mitotic spindle pole body; nucleolus; nucleus; rRNA processing,PF05178;PF12936;,,,,,,,,,KRI1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] comp128853_c0_seq1,846,41.844,0.27078043,0,0,,7.00E-12,Q6DDV0,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128853_c0_seq2,771,42.2827,0.29145322,0,0,,5.00E-06,Q2TL60,Zinc finger protein 667 (Myocardial ischemic preconditioning up-regulated protein 1),Zinc finger protein 667 (Myocardial ischemic preconditioning up-regulated protein 1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN667_MOUSE,Mus musculus (Mouse),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp128853_c0_seq3,870,41.7241,0.29164169,0,0,,2.00E-06,Q3SY52,Zinc finger protein interacting with ribonucleoprotein K (Zinc finger protein 762),Zinc finger protein interacting with ribonucleoprotein K (Zinc finger protein 762),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZIK1_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128853_c0_seq4,747,42.4364,0.26842153,0,0,,1.00E-11,Q6DDV0,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128855_c0_seq1,635,43.7795,0.43997555,0,0,,2.00E-07,O15164,Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),GO:0055074; GO:0071391; GO:0003682; GO:0005829; GO:0034056; GO:0070577; GO:0008285; GO:0045892; GO:0005719; GO:0005634; GO:0005726; GO:0045893; GO:0046777; GO:0030163; GO:0004672; GO:0005102; GO:0042981; GO:0031647; GO:0070562; GO:0043565; GO:0003713; GO:0006366; GO:0004842; GO:0008270,"calcium ion homeostasis; cellular response to estrogen stimulus; chromatin binding; cytosol; estrogen response element binding; histone acetyl-lysine binding; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nuclear euchromatin; nucleus; perichromatin fibrils; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein catabolic process; protein kinase activity; receptor binding; regulation of apoptotic process; regulation of protein stability; regulation of vitamin D receptor signaling pathway; sequence-specific DNA binding; transcription coactivator activity; transcription from RNA polymerase II promoter; ubiquitin-protein ligase activity; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TIF1A_HUMAN,Homo sapiens (Human),"calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]" comp128865_c0_seq1,382,45.288,0.66320801,18,0,,5.00E-17,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,7.00E-20,CHOYP_LOC100030710.4.4,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp128865_c0_seq2,314,45.8599,0.66414336,0,0,,,,,,,,,3.00E-11,CHOYP_LOC100030710.2.4,,,,,,,,, comp128866_c0_seq1,1581,43.1373,0.89830719,99,119,,1.00E-26,Q8K1C7,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT14_MOUSE,Mus musculus (Mouse), comp128870_c0_seq1,403,39.206,0.49510109,8,30,,1.00E-09,Q9HCE3,Zinc finger protein 532,Zinc finger protein 532,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16622;PF13912;,,,,,,,,,ZN532_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp128870_c0_seq2,855,37.6608,0.28879932,39,55,,2.00E-06,Q8N1G0,Zinc finger protein 687,Zinc finger protein 687,GO:0003677; GO:0046872; GO:0005730; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16622;,,,,,,,,,ZN687_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128873_c0_seq1,974,44.4559,0.35714323,24,100,,8.00E-108,Q8BG19,Transmembrane and TPR repeat-containing protein 4,Transmembrane and TPR repeat-containing protein 4,GO:0016021,integral to membrane,PF08409;PF00515;PF13181;,3.00E-17,CHOYP_TMTC4.1.1,,,,,,,TMTC4_MOUSE,Mus musculus (Mouse), comp128874_c0_seq1,267,42.3221,0.33647679,0,0,,1.00E-05,Q60773,Cyclin-dependent kinase 4 inhibitor D (p19-INK4d),Cyclin-dependent kinase 4 inhibitor D (p19-INK4d),GO:0000731; GO:0000082; GO:0048102; GO:0007050; GO:0004861; GO:0005737; GO:0030308; GO:0008285; GO:0043154; GO:1902230; GO:0005634; GO:0000079; GO:0009411; GO:0032526; GO:0033280; GO:0007605,DNA synthesis involved in DNA repair; G1/S transition of mitotic cell cycle; autophagic cell death; cell cycle arrest; cyclin-dependent protein serine/threonine kinase inhibitor activity; cytoplasm; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity; response to UV; response to retinoic acid; response to vitamin D; sensory perception of sound,,,,,,,,,,CDN2D_MOUSE,Mus musculus (Mouse),autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605] comp128874_c0_seq2,581,44.7504,0.48224575,6,41,,2.00E-59,Q8VBX0,Ankyrin repeat and SOCS box protein 13 (ASB-13),Ankyrin repeat and SOCS box protein 13 (ASB-13),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,2.00E-44,ruditapes_c7437,,,,,ASB13_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp128890_c0_seq1,844,35.545,0.52764376,888,6189,,3.00E-34,Q6AVK1,Costars family protein,Costars family protein,,,PF14705;,5.00E-19,CHOYP_CEG1A.3.6,,,,,,,COSA_ORYSJ,Oryza sativa subsp. japonica (Rice), comp128891_c0_seq1,1537,37.1503,0.86828706,543,5133,,1.00E-41,O00338,Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2),Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2),GO:0050427; GO:0009308; GO:0005829; GO:0015630; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine metabolic process; cytosol; microtubule cytoskeleton; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1C2_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; sulfation [GO:0051923] comp128893_c0_seq2,1658,48.1906,0.6545214,5,18,,6.00E-14,P55200,Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],GO:0006306; GO:0071339; GO:0009952; GO:0003682; GO:0035162; GO:0043984; GO:0070577; GO:0042800; GO:0008285; GO:0045944; GO:0051569; GO:0006351; GO:0045322; GO:0008270,"DNA methylation; MLL1 complex; anterior/posterior pattern specification; chromatin binding; embryonic hemopoiesis; histone H4-K16 acetylation; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of histone H3-K4 methylation; transcription, DNA-dependent; unmethylated CpG binding; zinc ion binding",PF05965;PF05964;PF00628;PF00856;PF02008;,,,,,,,,,MLL1_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; circadian regulation of gene expression [GO:0032922]; cognition [GO:0050890]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of gene expression [GO:0010468]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]" comp128893_c0_seq3,1781,48.2875,0.65686295,2,0,,1.00E-85,Q8NEZ4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,7.00E-91,CHOYP_LOC591084.1.2,,,,,,,MLL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128898_c0_seq1,1276,43.7304,0.92220382,953,5490,,1.00E-87,Q9MYP6,17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),GO:0005813; GO:0005829; GO:0004303; GO:0006706; GO:0047045,centrosome; cytosol; estradiol 17-beta-dehydrogenase activity; steroid catabolic process; testosterone 17-beta-dehydrogenase (NADP+) activity,,1.00E-55,CHOYP_DHB14.1.1,1.00E-71,ruditapes_c9908,,,,,DHB14_BOVIN,Bos taurus (Bovine),steroid catabolic process [GO:0006706] comp128902_c0_seq1,472,45.5508,0.41080608,40,18,,,,,,,,,5.00E-48,CHOYP_LOC101079642.1.1,3.00E-54,ruditapes_c14573,,,,,,, comp128904_c0_seq1,736,37.9076,0.72292338,8638,10950,,2.00E-23,Q02369,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (CI-B22) (NADH-ubiquinone oxidoreductase B22 subunit),NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (CI-B22) (NADH-ubiquinone oxidoreductase B22 subunit),GO:0005747; GO:0055114,mitochondrial respiratory chain complex I; oxidation-reduction process,PF05347;,,,1.00E-11,ruditapes_lrc23729,,,,,NDUB9_BOVIN,Bos taurus (Bovine),"mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitophagy in response to mitochondrial depolarization [GO:0098779]" comp128909_c1_seq1,730,50,0.70237941,54,14,,2.00E-57,Q60841,Reelin (EC 3.4.21.-) (Reeler protein),Reelin (EC 3.4.21.-) (Reeler protein),GO:0097114; GO:0008306; GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0016358; GO:0005615; GO:0010001; GO:0021766; GO:0097477; GO:0007616; GO:0046872; GO:0018108; GO:0032793; GO:0032008; GO:2000969; GO:0061003; GO:2000463; GO:1902078; GO:1900273; GO:0010976; GO:0014068; GO:0061098; GO:0051057; GO:0090129; GO:0051968; GO:0097107; GO:0097119; GO:0005578; GO:0006508; GO:0097120; GO:0038026; GO:2000310; GO:0050795; GO:0048265; GO:0008236; GO:0021511; GO:0021517,"N-methyl-D-aspartate receptor clustering; associative learning; axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; dendrite development; extracellular space; glial cell differentiation; hippocampus development; lateral motor column neuron migration; long-term memory; metal ion binding; peptidyl-tyrosine phosphorylation; positive regulation of CREB transcription factor activity; positive regulation of TOR signaling cascade; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; positive regulation of dendritic spine morphogenesis; positive regulation of excitatory postsynaptic membrane potential; positive regulation of lateral motor column neuron migration; positive regulation of long-term synaptic potentiation; positive regulation of neuron projection development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of protein tyrosine kinase activity; positive regulation of small GTPase mediated signal transduction; positive regulation of synapse maturation; positive regulation of synaptic transmission, glutamatergic; postsynaptic density assembly; postsynaptic density protein 95 clustering; proteinaceous extracellular matrix; proteolysis; receptor localization to synapse; reelin-mediated signaling pathway; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of behavior; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development",PF02014;,,,,,,,,,RELN_MOUSE,Mus musculus (Mouse),"associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex development [GO:0021987]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density assembly [GO:0097107]; postsynaptic density protein 95 clustering [GO:0097119]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of gene expression [GO:0010468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]" comp128911_c1_seq1,1372,45.9913,0.40001026,33,96,,2.00E-105,Q28BX9,C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein),C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein),GO:0005509; GO:0005544; GO:0005938; GO:0030659; GO:0038028; GO:0065002; GO:0010828; GO:0090314; GO:0031340; GO:0032587,calcium ion binding; calcium-dependent phospholipid binding; cell cortex; cytoplasmic vesicle membrane; insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; intracellular protein transmembrane transport; positive regulation of glucose transport; positive regulation of protein targeting to membrane; positive regulation of vesicle fusion; ruffle membrane,PF00168;,,,,,,,,,K0528_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340] comp128911_c2_seq1,809,46.9716,0.57003803,2,0,,,,,,,,,2.00E-107,CHOYP_LOC100865656.1.1,,,,,,,,, comp128911_c2_seq2,1122,49.6435,0.62631697,29,8,,3.00E-133,Q28BX9,C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein),C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein),GO:0005509; GO:0005544; GO:0005938; GO:0030659; GO:0038028; GO:0065002; GO:0010828; GO:0090314; GO:0031340; GO:0032587,calcium ion binding; calcium-dependent phospholipid binding; cell cortex; cytoplasmic vesicle membrane; insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; intracellular protein transmembrane transport; positive regulation of glucose transport; positive regulation of protein targeting to membrane; positive regulation of vesicle fusion; ruffle membrane,PF00168;,,,,,,,,,K0528_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340] comp128916_c1_seq2,659,47.648,0.2945479,9,0,,1.00E-84,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,4.00E-64,CHOYP_LOC100123553.1.1,,,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128918_c0_seq3,899,36.5962,0.67786481,0,0,,4.00E-14,P38040,Guanine nucleotide-binding protein subunit gamma-1,Guanine nucleotide-binding protein subunit gamma-1,GO:0007186; GO:0003924; GO:0007015; GO:0045176; GO:0055059; GO:0061343; GO:0007391; GO:0035050; GO:0003015; GO:0005834; GO:0007637; GO:0008360; GO:0004871,G-protein coupled receptor signaling pathway; GTPase activity; actin filament organization; apical protein localization; asymmetric neuroblast division; cell adhesion involved in heart morphogenesis; dorsal closure; embryonic heart tube development; heart process; heterotrimeric G-protein complex; proboscis extension reflex; regulation of cell shape; signal transducer activity,PF00631;,,,,,,,,,GBG1_DROME,Drosophila melanogaster (Fruit fly),actin filament organization [GO:0007015]; apical protein localization [GO:0045176]; asymmetric neuroblast division [GO:0055059]; cell adhesion [GO:0007155]; cell adhesion involved in heart morphogenesis [GO:0061343]; convergent extension involved in gastrulation [GO:0060027]; dorsal closure [GO:0007391]; embryonic heart tube development [GO:0035050]; establishment or maintenance of cytoskeleton polarity involved in gastrulation [GO:0003380]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; mesectoderm development [GO:0048383]; neurogenesis [GO:0022008]; proboscis extension reflex [GO:0007637]; regulation of cell shape [GO:0008360]; regulation of gastrulation [GO:0010470]; regulation of myosin II filament organization [GO:0043519] comp128918_c0_seq5,833,35.6543,0.65944281,0,0,,4.00E-14,P38040,Guanine nucleotide-binding protein subunit gamma-1,Guanine nucleotide-binding protein subunit gamma-1,GO:0007186; GO:0003924; GO:0007015; GO:0045176; GO:0055059; GO:0061343; GO:0007391; GO:0035050; GO:0003015; GO:0005834; GO:0007637; GO:0008360; GO:0004871,G-protein coupled receptor signaling pathway; GTPase activity; actin filament organization; apical protein localization; asymmetric neuroblast division; cell adhesion involved in heart morphogenesis; dorsal closure; embryonic heart tube development; heart process; heterotrimeric G-protein complex; proboscis extension reflex; regulation of cell shape; signal transducer activity,PF00631;,5.00E-13,CHOYP_LOC100875987.2.2,,,,,,,GBG1_DROME,Drosophila melanogaster (Fruit fly),actin filament organization [GO:0007015]; apical protein localization [GO:0045176]; asymmetric neuroblast division [GO:0055059]; cell adhesion [GO:0007155]; cell adhesion involved in heart morphogenesis [GO:0061343]; convergent extension involved in gastrulation [GO:0060027]; dorsal closure [GO:0007391]; embryonic heart tube development [GO:0035050]; establishment or maintenance of cytoskeleton polarity involved in gastrulation [GO:0003380]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; mesectoderm development [GO:0048383]; neurogenesis [GO:0022008]; proboscis extension reflex [GO:0007637]; regulation of cell shape [GO:0008360]; regulation of gastrulation [GO:0010470]; regulation of myosin II filament organization [GO:0043519] comp128918_c0_seq6,424,42.6887,0.62362783,0,0,,,,,,,,,3.00E-12,CHOYP_AGAP_AGAP010589.1.1,,,,,,,,, comp128919_c0_seq1,696,45.6897,0.53405764,0,0,,3.00E-10,Q7Z4H8,KDEL motif-containing protein 2,KDEL motif-containing protein 2,GO:0005788,endoplasmic reticulum lumen,PF00630;PF05686;,8.00E-73,CHOYP_POGLUT1.1.1,,,,,,,KDEL2_HUMAN,Homo sapiens (Human),glycolipid metabolic process [GO:0006664] comp128919_c0_seq4,716,45.3911,0.55789091,0,0,,1.00E-101,Q8BYB9,Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1),Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase) (EC 2.4.2.26),GO:0035251; GO:0035252; GO:0072358; GO:0005788; GO:0006493; GO:0008593,UDP-glucosyltransferase activity; UDP-xylosyltransferase activity; cardiovascular system development; endoplasmic reticulum lumen; protein O-linked glycosylation; regulation of Notch signaling pathway,PF05686;,,,,,,,,,PGLT1_MOUSE,Mus musculus (Mouse),axial mesoderm development [GO:0048318]; cardiovascular system development [GO:0072358]; glycolipid metabolic process [GO:0006664]; paraxial mesoderm development [GO:0048339]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493]; regulation of Notch signaling pathway [GO:0008593]; somitogenesis [GO:0001756] comp128921_c0_seq1,897,34.7826,0.63315578,69592,73268,,3.00E-25,Q4PM47,40S ribosomal protein S29,40S ribosomal protein S29,GO:0046872; GO:0005840; GO:0003735; GO:0006412,metal ion binding; ribosome; structural constituent of ribosome; translation,PF00253;,4.00E-40,CHOYP_RS29.5.6,1.00E-50,ruditapes_c632,,,,,RS29_IXOSC,Ixodes scapularis (Black-legged tick) (Deer tick),translation [GO:0006412] comp128923_c1_seq1,1402,47.4322,0.50955209,98,51,,0,Q2TBP4,POC1 centriolar protein homolog A (WD repeat-containing protein 51A),POC1 centriolar protein homolog A (WD repeat-containing protein 51A),GO:0030030; GO:0005814; GO:0005932,cell projection organization; centriole; microtubule basal body,PF00400;,0,CHOYP_LOC100378584.3.3,,,,,,,POC1A_BOVIN,Bos taurus (Bovine),cell projection organization [GO:0030030] comp128928_c1_seq1,746,41.2869,0.89281759,45,84,,2.00E-35,P56965,"N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1)","N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1)",GO:0000052; GO:0005737; GO:0016403; GO:0006809; GO:0045429; GO:0017014; GO:0003073; GO:0008270,citrulline metabolic process; cytoplasm; dimethylargininase activity; nitric oxide biosynthetic process; positive regulation of nitric oxide biosynthetic process; protein nitrosylation; regulation of systemic arterial blood pressure; zinc ion binding,,4.00E-26,CHOYP_ABCB6.2.3,,,,,,,DDAH1_BOVIN,Bos taurus (Bovine),arginine catabolic process [GO:0006527]; citrulline metabolic process [GO:0000052]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073] comp128932_c0_seq1,896,44.8661,0.29476781,20,44,,1.00E-60,Q5RF15,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF12796;PF07714;,5.00E-32,CHOYP_LOC576866.1.1,,,,,,,TNI3K_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp128935_c1_seq1,3272,40.709,0.56218435,63,1068,,5.00E-09,Q96IR2,Zinc finger protein 845,Zinc finger protein 845,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,3.00E-54,CHOYP_XFIN.1.4,,,,,,,ZN845_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp128936_c1_seq1,715,44.1958,0.78970743,37,57,,3.00E-09,A0PJR5,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial","Enoyl-CoA hydratase domain-containing protein 3, mitochondrial",GO:0003824; GO:0005739,catalytic activity; mitochondrion,PF00378;,,,,,,,,,ECHD3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),metabolic process [GO:0008152] comp128938_c0_seq1,1337,31.264,0.47121552,860,7863,,4.00E-15,Q20591,V-type proton ATPase subunit e (V-ATPase subunit e) (Vacuolar proton pump subunit e),V-type proton ATPase subunit e (V-ATPase subunit e) (Vacuolar proton pump subunit e),GO:0015991; GO:0043296; GO:0016324; GO:0009792; GO:0010172; GO:0015078; GO:0016787; GO:0016021; GO:0033179; GO:0060142,"ATP hydrolysis coupled proton transport; apical junction complex; apical plasma membrane; embryo development ending in birth or egg hatching; embryonic body morphogenesis; hydrogen ion transmembrane transporter activity; hydrolase activity; integral to membrane; proton-transporting V-type ATPase, V0 domain; regulation of syncytium formation by plasma membrane fusion",PF05493;,4.00E-23,CHOYP_LOC753676.1.1,4.00E-39,ruditapes_c51,,,,,VA0E_CAEEL,Caenorhabditis elegans,ATP hydrolysis coupled proton transport [GO:0015991]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic body morphogenesis [GO:0010172]; regulation of syncytium formation by plasma membrane fusion [GO:0060142] comp128939_c0_seq2,478,41.841,0.6988023,8,27,,4.00E-47,Q6VVX2,Collagen type IV alpha-3-binding protein (Ceramide transfer protein),Collagen type IV alpha-3-binding protein (Ceramide transfer protein),GO:0035621; GO:0005794; GO:0005829; GO:0005783; GO:0070273,ER to Golgi ceramide transport; Golgi apparatus; cytosol; endoplasmic reticulum; phosphatidylinositol-4-phosphate binding,PF00169;PF01852;,8.00E-58,CHOYP_C43BP.1.1,,,,,,,C43BP_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),ER to Golgi ceramide transport [GO:0035621] comp128939_c0_seq3,478,41.0042,0.669933,0,0,,8.00E-16,D2KC46,Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2),Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2),GO:0035621; GO:0005794; GO:0097001; GO:0051861; GO:0046836; GO:0017089; GO:0016020; GO:0070273; GO:0015031; GO:0005802,ER to Golgi ceramide transport; Golgi apparatus; ceramide binding; glycolipid binding; glycolipid transport; glycolipid transporter activity; membrane; phosphatidylinositol-4-phosphate binding; protein transport; trans-Golgi network,PF08718;PF00169;,,,,,,,,,PKHA8_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),ER to Golgi ceramide transport [GO:0035621]; lipid transport [GO:0006869]; protein transport [GO:0015031] comp128943_c0_seq1,1149,50.1305,0.42989132,2,18,,2.00E-73,O46037,Vinculin,Vinculin,GO:0003779; GO:0015629; GO:0007155; GO:0005737; GO:0007016; GO:0005925; GO:0048812; GO:0006909; GO:0005886; GO:0005198,actin binding; actin cytoskeleton; cell adhesion; cytoplasm; cytoskeletal anchoring at plasma membrane; focal adhesion; neuron projection morphogenesis; phagocytosis; plasma membrane; structural molecule activity,PF01044;,1.00E-129,CHOYP_LOC100744506.1.1,,,,,,,VINC_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909] comp128943_c0_seq2,314,56.3694,0.55248806,5,17,,,,,,,,,6.00E-32,CHOYP_LOC100899991.1.1,,,,,,,,, comp128943_c0_seq3,1083,49.3998,0.39388467,4,0,,2.00E-75,O46037,Vinculin,Vinculin,GO:0003779; GO:0015629; GO:0007155; GO:0005737; GO:0007016; GO:0005925; GO:0048812; GO:0006909; GO:0005886; GO:0005198,actin binding; actin cytoskeleton; cell adhesion; cytoplasm; cytoskeletal anchoring at plasma membrane; focal adhesion; neuron projection morphogenesis; phagocytosis; plasma membrane; structural molecule activity,PF01044;,9.00E-100,CHOYP_LOC100371677.1.1,,,,,,,VINC_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909] comp128943_c2_seq1,428,51.4019,0.5418977,8,19,,1.00E-45,Q04615,Vinculin (Metavinculin) (Fragment),Vinculin (Metavinculin) (Fragment),GO:0015629; GO:0005912; GO:0007155; GO:0005737; GO:0005886; GO:0005198,actin cytoskeleton; adherens junction; cell adhesion; cytoplasm; plasma membrane; structural molecule activity,PF01044;,2.00E-65,CHOYP_PHUM_PHUM397210.1.1,5.00E-58,ruditapes_c22068,,,,,VINC_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155] comp128944_c0_seq1,2909,40.0481,0.55337995,10,161,,2.00E-26,Q08E02,Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1),Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1),GO:0071222; GO:0007623; GO:0010871; GO:0034144; GO:0000122; GO:0000790; GO:0043565; GO:0003700; GO:0003707; GO:0044212; GO:0006351; GO:0008270,"cellular response to lipopolysaccharide; circadian rhythm; negative regulation of receptor biosynthetic process; negative regulation of toll-like receptor 4 signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription regulatory region DNA binding; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,NR1D1_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; circadian regulation of gene expression [GO:0032922]; circadian temperature homeostasis [GO:0060086]; glycogen biosynthetic process [GO:0005978]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasomal protein catabolic process [GO:0010498]; regulation of cholesterol homeostasis [GO:2000188]; regulation of circadian rhythm [GO:0042752]; regulation of fat cell differentiation [GO:0045598]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to leptin [GO:0044321]; transcription, DNA-templated [GO:0006351]" comp128944_c0_seq2,2950,40.1695,0.54292488,118,419,,3.00E-28,Q08893,Ecdysone-inducible protein E75 (Nuclear receptor subfamily 1 group D member 3),Ecdysone-inducible protein E75 (Nuclear receptor subfamily 1 group D member 3),GO:0005634; GO:0043565; GO:0003707; GO:0004887; GO:0008270,nucleus; sequence-specific DNA binding; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,5.00E-70,CHOYP_DANA_GF24303.1.1,,,,,,,E75_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),"transcription, DNA-templated [GO:0006351]" comp128948_c0_seq1,1757,43.0848,0.55452766,0,117,,3.00E-12,P01023,Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5),Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5),GO:0007597; GO:0005829; GO:0005615; GO:0070062; GO:0019966; GO:0001869; GO:0030168; GO:0031093; GO:0002576; GO:0051056; GO:0004867; GO:0007264; GO:0048863; GO:0043120,"blood coagulation, intrinsic pathway; cytosol; extracellular space; extracellular vesicular exosome; interleukin-1 binding; negative regulation of complement activation, lectin pathway; platelet activation; platelet alpha granule lumen; platelet degranulation; regulation of small GTPase mediated signal transduction; serine-type endopeptidase inhibitor activity; small GTPase mediated signal transduction; stem cell differentiation; tumor necrosis factor binding",PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,7.00E-66,CHOYP_PHUM_PHUM289860.1.1,,,,,,,A2MG_HUMAN,Homo sapiens (Human),"blood coagulation, intrinsic pathway [GO:0007597]; extracellular matrix disassembly [GO:0022617]; negative regulation of complement activation, lectin pathway [GO:0001869]; platelet degranulation [GO:0002576]; regulation of small GTPase mediated signal transduction [GO:0051056]; stem cell differentiation [GO:0048863]" comp128948_c0_seq2,1342,43.2936,0.56066493,0,0,,8.00E-30,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp128949_c0_seq1,917,36.4231,0.88057659,36,244,,5.00E-98,Q32LJ2,ADP-ribosylation factor-related protein 1 (ARF-related protein 1),ADP-ribosylation factor-related protein 1 (ARF-related protein 1),GO:0005525; GO:0005794; GO:0043001; GO:0034067; GO:0042147; GO:0007264; GO:0005802,"GTP binding; Golgi apparatus; Golgi to plasma membrane protein transport; protein localization to Golgi apparatus; retrograde transport, endosome to Golgi; small GTPase mediated signal transduction; trans-Golgi network",PF00025;,2.00E-70,CHOYP_LOC101072591.1.1,,,,,,,ARFRP_BOVIN,Bos taurus (Bovine),"gastrulation [GO:0007369]; Golgi to plasma membrane protein transport [GO:0043001]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; small GTPase mediated signal transduction [GO:0007264]" comp128957_c0_seq1,1230,40.7317,0.63835773,5045,27833,,3.00E-52,Q17QN3,Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN),Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN),GO:0003723; GO:0005634; GO:0030529,RNA binding; nucleus; ribonucleoprotein complex,PF01423;,1.00E-67,CHOYP_RSMB.1.2,1.00E-103,ruditapes_c14221,,,,,RSMN_BOVIN,Bos taurus (Bovine),"mRNA splicing, via spliceosome [GO:0000398]" comp128963_c0_seq1,1509,41.8158,0.5246149,78,140,,6.00E-83,Q03601,RING finger protein nhl-1,RING finger protein nhl-1,GO:0008270,zinc ion binding,PF01436;PF00097;,2.00E-66,CHOYP_LOC656122.1.1,,,,,,,NHL1_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567] comp128966_c1_seq1,590,42.2034,0.23149303,14,56,,3.00E-55,Q58CU3,HSPB1-associated protein 1 (27 kDa heat shock protein-associated protein 1),HSPB1-associated protein 1 (27 kDa heat shock protein-associated protein 1),GO:0005737; GO:0006950,cytoplasm; response to stress,,3.00E-27,CHOYP_HBAP1.1.1,,,,,,,HBAP1_BOVIN,Bos taurus (Bovine), comp128975_c1_seq1,1583,38.7871,0.3932262,177,497,,4.00E-72,Q95M17,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,,,,,,,,,CHIA_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp128977_c0_seq1,1163,36.1995,0.39819405,4574,11850,,1.00E-34,Q0MQE6,"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)",GO:0008137; GO:0016021; GO:0006120; GO:0005747,"NADH dehydrogenase (ubiquinone) activity; integral to membrane; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I",PF05821;,,,1.00E-14,ruditapes_c53,,,,,NDUB8_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),"mitochondrial electron transport, NADH to ubiquinone [GO:0006120]" comp128982_c0_seq1,788,36.802,0.61091852,36,300,,1.00E-29,Q5TYM5,Protein FAM72A (Latent membrane protein 1-induced protein) (LMP1-induced protein) (LMPIP),Protein FAM72A (Latent membrane protein 1-induced protein) (LMP1-induced protein) (LMPIP),GO:0005739,mitochondrion,PF14976;,,,,,,,,,FA72A_HUMAN,Homo sapiens (Human), comp128985_c0_seq1,824,34.2233,0.45794083,1313,4153,,2.00E-37,Q9VFB2,"28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt)","28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt)",GO:0005763; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; structural constituent of ribosome; translation,PF00338;,,,9.00E-20,ruditapes2_c152,,,,,RT10_DROME,Drosophila melanogaster (Fruit fly),sensory perception of pain [GO:0019233]; translation [GO:0006412] comp128989_c1_seq2,1279,33.9328,0.31244471,4,0,,9.00E-17,B2GV91,LYR motif-containing protein 2,LYR motif-containing protein 2,GO:0005739,mitochondrion,PF05347;,,,,,,,,,LYRM2_RAT,Rattus norvegicus (Rat), comp128990_c0_seq2,1140,41.4035,0.59427129,25,48,,6.00E-83,Q15329,Transcription factor E2F5 (E2F-5),Transcription factor E2F5 (E2F-5),GO:0003677; GO:0005737; GO:0000278; GO:0005654; GO:0009887; GO:0045944; GO:0051726; GO:0003700; GO:0005667; GO:0006367; GO:0007179,DNA binding; cytoplasm; mitotic cell cycle; nucleoplasm; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway,PF16421;PF02319;,2.00E-38,CHOYP_E2F4.1.1,,,,,,,E2F5_HUMAN,Homo sapiens (Human),"cell projection organization [GO:0030030]; organ morphogenesis [GO:0009887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; transcription, DNA-templated [GO:0006351]" comp129001_c1_seq1,1191,38.707,0.47745513,100,269,,3.00E-17,Q60432,Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170),Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170),GO:0005524; GO:0005788; GO:0006950,ATP binding; endoplasmic reticulum lumen; response to stress,PF00012;,1.00E-40,CHOYP_HYOU1.3.3,,,,,,,HYOU1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus), comp129003_c1_seq2,683,39.9707,0.42222313,8,9,,4.00E-115,Q8R1Z9,RING finger protein 121,RING finger protein 121,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,,5.00E-100,CHOYP_RN121.1.1,,,,,,,RN121_MOUSE,Mus musculus (Mouse),endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433] comp129006_c1_seq1,697,45.7676,0.49920637,46,5,,8.00E-110,O00763,Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)],Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)],GO:0005524; GO:0003989; GO:0006084; GO:0004075; GO:0006768; GO:0006853; GO:0044255; GO:0005829; GO:0012505; GO:0006112; GO:0006633; GO:2001295; GO:0016020; GO:0046872; GO:0005739; GO:0031325; GO:0051289,ATP binding; acetyl-CoA carboxylase activity; acetyl-CoA metabolic process; biotin carboxylase activity; biotin metabolic process; carnitine shuttle; cellular lipid metabolic process; cytosol; endomembrane system; energy reserve metabolic process; fatty acid biosynthetic process; malonyl-CoA biosynthetic process; membrane; metal ion binding; mitochondrion; positive regulation of cellular metabolic process; protein homotetramerization,PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;,,,,,,,,,ACACB_HUMAN,Homo sapiens (Human),acetyl-CoA metabolic process [GO:0006084]; biotin metabolic process [GO:0006768]; carnitine shuttle [GO:0006853]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of cellular metabolic process [GO:0031325]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of glucose metabolic process [GO:0010906]; response to nutrient levels [GO:0031667] comp129006_c1_seq3,641,47.4259,0.50234864,0,0,,,,,,,,,3.00E-103,CHOYP_ACACA.2.7,,,,,,,,, comp129010_c2_seq1,1534,46.4798,0.36245588,24,61,,8.00E-39,Q9P2D8,Protein unc-79 homolog,Protein unc-79 homolog,GO:0048149; GO:0016021; GO:0034220; GO:0035264; GO:0005886,behavioral response to ethanol; integral to membrane; ion transmembrane transport; multicellular organism growth; plasma membrane,,8.00E-58,CHOYP_UNC79.4.4,,,,,,,UNC79_HUMAN,Homo sapiens (Human),behavioral response to ethanol [GO:0048149]; ion transmembrane transport [GO:0034220]; multicellular organism growth [GO:0035264] comp129010_c2_seq2,979,46.8846,0.35412741,2,0,,3.00E-13,Q0KK59,Protein unc-79 homolog,Protein unc-79 homolog,GO:0048149; GO:0016021; GO:0035264,behavioral response to ethanol; integral to membrane; multicellular organism growth,,5.00E-58,CHOYP_UNC79.4.4,,,,,,,UNC79_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] comp129017_c0_seq1,883,32.0498,0.27241946,874,6388,,2.00E-37,Q9NQP4,Prefoldin subunit 4 (Protein C-1),Prefoldin subunit 4 (Protein C-1),GO:0051084; GO:0051087; GO:0005829; GO:0005739; GO:0005634; GO:0016272,'de novo' posttranslational protein folding; chaperone binding; cytosol; mitochondrion; nucleus; prefoldin complex,PF01920;,3.00E-29,CHOYP_LOC100564354.1.1,,,,,,,PFD4_HUMAN,Homo sapiens (Human),protein folding [GO:0006457] comp129019_c0_seq1,867,45.5594,0.29064535,0,0,,1.00E-59,P11654,Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),GO:0005789; GO:0051028; GO:0031965; GO:0005643; GO:0046983; GO:0015031; GO:0017056,endoplasmic reticulum membrane; mRNA transport; nuclear membrane; nuclear pore; protein dimerization activity; protein transport; structural constituent of nuclear pore,PF02368;,,,,,,,,,PO210_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp129019_c0_seq2,2477,44.7719,0.35492424,92,122,,2.00E-90,P11654,Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),GO:0005789; GO:0051028; GO:0031965; GO:0005643; GO:0046983; GO:0015031; GO:0017056,endoplasmic reticulum membrane; mRNA transport; nuclear membrane; nuclear pore; protein dimerization activity; protein transport; structural constituent of nuclear pore,PF02368;,2.00E-61,CHOYP_NUP210.1.1,,,,,,,PO210_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp129021_c0_seq2,1209,36.5591,0.44748551,1,8,,5.00E-34,Q6P791,Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18),Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18),GO:0005794; GO:0071986; GO:0016049; GO:0034613; GO:0071230; GO:0042632; GO:0032439; GO:0007032; GO:0005085; GO:0005765; GO:0005764; GO:0032418; GO:0007040; GO:0005886; GO:0043410; GO:0032008; GO:0010874; GO:0010872; GO:0060620; GO:0001919,Golgi apparatus; Ragulator complex; cell growth; cellular protein localization; cellular response to amino acid stimulus; cholesterol homeostasis; endosome localization; endosome organization; guanyl-nucleotide exchange factor activity; lysosomal membrane; lysosome; lysosome localization; lysosome organization; plasma membrane; positive regulation of MAPK cascade; positive regulation of TOR signaling cascade; regulation of cholesterol efflux; regulation of cholesterol esterification; regulation of cholesterol import; regulation of receptor recycling,PF15454;,,,,,,,,,LTOR1_RAT,Rattus norvegicus (Rat),cell growth [GO:0016049]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; cholesterol homeostasis [GO:0042632]; endosome localization [GO:0032439]; endosome organization [GO:0007032]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of TOR signaling [GO:0032008]; regulation of cholesterol efflux [GO:0010874]; regulation of cholesterol esterification [GO:0010872]; regulation of cholesterol import [GO:0060620]; regulation of receptor recycling [GO:0001919] comp129023_c0_seq4,1096,44.708,0.42476466,0,0,,7.00E-38,Q6NRD5,Exonuclease 3'-5' domain-containing protein 1 (Exonuclease 3'-5' domain-like-containing protein 1),piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;,,,,,,,,,EXD1_XENLA,Xenopus laevis (African clawed frog),gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587] comp129028_c0_seq1,1542,34.1764,0.49511412,1376,1541,,,,,,,,,1.00E-24,CHOYP_LOC575509.1.2,,,,,,,,, comp129029_c0_seq1,835,46.1078,0.38446195,35,183,,6.00E-53,P23610,Factor VIII intron 22 protein (CpG island protein),Factor VIII intron 22 protein (CpG island protein),GO:0005634,nucleus,,2.00E-106,CHOYP_BRAFLDRAFT_115297.1.1,,,,,,,F8I2_HUMAN,Homo sapiens (Human), comp129031_c0_seq1,1643,42.9702,0.66000265,0,0,,2.00E-25,Q6AYJ3,Spermatogenesis associated 6-like protein,Spermatogenesis associated 6-like protein,,,PF14909;,,,,,,,,,SPA6L_RAT,Rattus norvegicus (Rat), comp129031_c0_seq3,1661,43.3474,0.61559853,0,0,,2.00E-22,Q99MU5,Spermatogenesis-associated protein 6 (Kinesin-related protein) (Spermatogenesis-related factor 1),Spermatogenesis-associated protein 6 (Kinesin-related protein) (Spermatogenesis-related factor 1),GO:0030154; GO:0005576; GO:0007275; GO:0007283,cell differentiation; extracellular region; multicellular organismal development; spermatogenesis,PF14909;,,,,,,,,,SPAT6_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; motile cilium assembly [GO:0044458]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp129031_c0_seq4,1687,42.7979,0.66083295,0,0,,2.00E-25,Q6AYJ3,Spermatogenesis associated 6-like protein,Spermatogenesis associated 6-like protein,,,PF14909;,1.00E-24,CHOYP_SPATA6.1.1,,,,,,,SPA6L_RAT,Rattus norvegicus (Rat), comp129033_c0_seq1,1091,37.6719,0.49285043,71,443,,3.00E-76,Q921Y2,U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3),U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3),GO:0005730; GO:0019843; GO:0006364; GO:0030529; GO:0030519,nucleolus; rRNA binding; rRNA processing; ribonucleoprotein complex; snoRNP binding,PF00163;PF01479;,6.00E-96,CHOYP_LOC100371776.3.3,,,,,,,IMP3_MOUSE,Mus musculus (Mouse),rRNA processing [GO:0006364] comp129042_c0_seq1,979,44.0245,0.55082422,0,0,,1.00E-36,Q6TLH3,CUE domain-containing protein 2,CUE domain-containing protein 2,GO:0005737; GO:0005634,cytoplasm; nucleus,,,,,,,,,,CUED2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129042_c0_seq2,1398,40.3433,0.49482738,0,0,,1.00E-43,Q9H467,CUE domain-containing protein 2,CUE domain-containing protein 2,GO:0005737; GO:0005634,cytoplasm; nucleus,PF02845;,,,,,,,,,CUED2_HUMAN,Homo sapiens (Human),negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of macrophage cytokine production [GO:0010936] comp129042_c0_seq3,1238,41.1147,0.53736095,0,0,,5.00E-36,Q6TLH3,CUE domain-containing protein 2,CUE domain-containing protein 2,GO:0005737; GO:0005634,cytoplasm; nucleus,,,,,,,,,,CUED2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129042_c0_seq4,1139,42.669,0.5047258,0,0,,2.00E-44,Q9H467,CUE domain-containing protein 2,CUE domain-containing protein 2,GO:0005737; GO:0005634,cytoplasm; nucleus,PF02845;,3.00E-30,CHOYP_LOC756750.1.1,,,,,,,CUED2_HUMAN,Homo sapiens (Human),negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of macrophage cytokine production [GO:0010936] comp129047_c0_seq1,1540,40.974,0.48878609,531,2213,,2.00E-78,Q13895,Bystin,Bystin,GO:0045177; GO:0007155; GO:0008283; GO:0005737; GO:0007565; GO:0000462; GO:0005730; GO:0001829,"apical part of cell; cell adhesion; cell proliferation; cytoplasm; female pregnancy; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleolus; trophectodermal cell differentiation",PF05291;,2.00E-174,CHOYP_BRAFLDRAFT_277920.1.1,,,,,,,BYST_HUMAN,Homo sapiens (Human),"brain development [GO:0007420]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; female pregnancy [GO:0007565]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; neuron differentiation [GO:0030182]; rRNA processing [GO:0006364]; trophectodermal cell differentiation [GO:0001829]" comp129048_c0_seq2,717,38.6332,0.26278416,0,0,,2.00E-35,P61025,Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334),Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334),GO:0007049; GO:0051301; GO:0016538,cell cycle; cell division; cyclin-dependent protein serine/threonine kinase regulator activity,PF01111;,1.00E-38,CHOYP_DSEC_GM26323.1.1,,,,,,,CKS1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]" comp129053_c0_seq1,1689,41.5631,0.50405565,9,14,,3.00E-81,Q62270,Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70),Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70),GO:0005524; GO:0005737; GO:0004715; GO:0038083; GO:0004713,ATP binding; cytoplasm; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine autophosphorylation; protein tyrosine kinase activity,PF07714;PF00017;PF14604;,,,,,,,,,SRMS_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell migration [GO:0016477]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp129053_c0_seq2,1679,42.168,0.56038746,15,17,,0,P41241,Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK),Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK),GO:0005524; GO:0005794; GO:0034332; GO:0007420; GO:0005911; GO:0071375; GO:0005813; GO:0035556; GO:0045121; GO:0070373; GO:0042997; GO:0045779; GO:0008285; GO:0032715; GO:0033673; GO:0010989; GO:0050765; GO:0004715; GO:0048709; GO:0005886; GO:0043406; GO:0046777; GO:0004713; GO:0060368; GO:0050863,ATP binding; Golgi apparatus; adherens junction organization; brain development; cell-cell junction; cellular response to peptide hormone stimulus; centrosome; intracellular signal transduction; membrane raft; negative regulation of ERK1 and ERK2 cascade; negative regulation of Golgi to plasma membrane protein transport; negative regulation of bone resorption; negative regulation of cell proliferation; negative regulation of interleukin-6 production; negative regulation of kinase activity; negative regulation of low-density lipoprotein particle clearance; negative regulation of phagocytosis; non-membrane spanning protein tyrosine kinase activity; oligodendrocyte differentiation; plasma membrane; positive regulation of MAP kinase activity; protein autophosphorylation; protein tyrosine kinase activity; regulation of Fc receptor mediated stimulatory signaling pathway; regulation of T cell activation,PF07714;PF00017;PF00018;,4.00E-150,CHOYP_PHUM_PHUM048780.1.1,,,,,,,CSK_MOUSE,Mus musculus (Mouse),adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to peptide hormone stimulus [GO:0071375]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of MAP kinase activity [GO:0043406]; protein phosphorylation [GO:0006468]; regulation of cytokine production [GO:0001817]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; regulation of T cell activation [GO:0050863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp129053_c0_seq3,748,43.4492,0.54007687,7,0,,2.00E-40,O73792,Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) (Fragment),Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) (Fragment),GO:0005524; GO:0001525; GO:0016021; GO:0018108; GO:0005886; GO:0004714,ATP binding; angiogenesis; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; transmembrane receptor protein tyrosine kinase activity,PF07714;,,,,,,,,,TIE1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507] comp129053_c0_seq4,1140,40.8772,0.51180303,6,0,,5.00E-59,P22607,Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333),Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333),GO:0005524; GO:0038095; GO:0007259; GO:0000165; GO:0061144; GO:0060385; GO:0070977; GO:0022010; GO:0002062; GO:0035988; GO:0090102; GO:0016023; GO:0048546; GO:0003416; GO:0001958; GO:0005783; GO:0007173; GO:0072148; GO:0005576; GO:0017134; GO:1902178; GO:0005007; GO:0045087; GO:0060113; GO:0008286; GO:0005887; GO:0009898; GO:0070307; GO:0002089; GO:0005764; GO:0002009; GO:0043066; GO:0048712; GO:0048640; GO:0050680; GO:0045839; GO:0045879; GO:0000122; GO:0048011; GO:0048471; GO:0048015; GO:0070374; GO:0090080; GO:0043065; GO:0090263; GO:0045597; GO:0008284; GO:0001938; GO:0043552; GO:0010518; GO:0031398; GO:0042511; GO:0042517; GO:0046777; GO:0048678; GO:0035019; GO:0021762,ATP binding; Fc-epsilon receptor signaling pathway; JAK-STAT cascade; MAPK cascade; alveolar secondary septum development; axonogenesis involved in innervation; bone maturation; central nervous system myelination; chondrocyte differentiation; chondrocyte proliferation; cochlea development; cytoplasmic membrane-bounded vesicle; digestive tract morphogenesis; endochondral bone growth; endochondral ossification; endoplasmic reticulum; epidermal growth factor receptor signaling pathway; epithelial cell fate commitment; extracellular region; fibroblast growth factor binding; fibroblast growth factor receptor signaling pathway involved in apoptotic process; fibroblast growth factor-activated receptor activity; innate immune response; inner ear receptor cell differentiation; insulin receptor signaling pathway; integral to plasma membrane; internal side of plasma membrane; lens fiber cell development; lens morphogenesis in camera-type eye; lysosome; morphogenesis of an epithelium; negative regulation of apoptotic process; negative regulation of astrocyte differentiation; negative regulation of developmental growth; negative regulation of epithelial cell proliferation; negative regulation of mitosis; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neurotrophin TRK receptor signaling pathway; perinuclear region of cytoplasm; phosphatidylinositol-mediated signaling; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; positive regulation of apoptotic process; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of phospholipase activity; positive regulation of protein ubiquitination; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; protein autophosphorylation; response to axon injury; somatic stem cell maintenance; substantia nigra development,PF07679;PF07714;,3.00E-105,CHOYP_PHUM_PHUM048780.1.1,,,,,,,FGFR3_HUMAN,Homo sapiens (Human),bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; JAK-STAT cascade [GO:0007259]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of Stat1 protein [GO:0042511]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; protein autophosphorylation [GO:0046777]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; skeletal system development [GO:0001501] comp129056_c0_seq1,2148,40.1304,0.4566064,291,12,,1.00E-15,Q6ZV65,Protein FAM47E,Protein FAM47E,,,PF14642;,6.00E-93,CHOYP_LOC100370211.1.1,,,,,,,FA47E_HUMAN,Homo sapiens (Human), comp129056_c0_seq2,2008,40.1892,0.44896653,75,3,,1.00E-15,Q6ZV65,Protein FAM47E,Protein FAM47E,,,PF14642;,2.00E-86,CHOYP_LOC100889336.1.1,3.00E-62,ruditapes_c10377,,,,,FA47E_HUMAN,Homo sapiens (Human), comp129063_c0_seq1,899,35.1502,0.47353143,32,126,,2.00E-06,Q96JF6,Zinc finger protein 594 (Zinc finger protein HZF18),Zinc finger protein 594 (Zinc finger protein HZF18),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN594_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129064_c0_seq1,1989,34.9925,0.39676022,2737,14630,,8.00E-150,Q3ZBD0,26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8),26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8),GO:0000502,proteasome complex,PF01398;PF13012;,0,CHOYP_PSD7.1.1,0,ruditapes2_c589,,,,,PSD7_BOVIN,Bos taurus (Bovine),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp129066_c0_seq1,874,33.524,0.32984682,40,63,,1.00E-09,Q6GPP1,Telomere length regulation protein TEL2 homolog,Telomere length regulation protein TEL2 homolog,GO:0000781; GO:0005737; GO:0016020; GO:0005634,"chromosome, telomeric region; cytoplasm; membrane; nucleus",PF10193;,,,,,,,,,TELO2_XENLA,Xenopus laevis (African clawed frog), comp129068_c0_seq1,979,44.3309,0.29151824,64,6,,7.00E-90,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,,,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129068_c1_seq1,3029,47.6395,0.39003635,185,81,,0,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,0,CHOYP_LOC100123553.1.1,7.00E-28,ruditapes_c18162,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129074_c0_seq3,1046,34.0344,0.69535168,27,0,,2.00E-07,Q17551,E3 ubiquitin-protein ligase rpm-1 (EC 6.3.2.-) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3),E3 ubiquitin-protein ligase rpm-1 (EC 6.3.2.-) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3),GO:0030424; GO:0010171; GO:0040011; GO:0043409; GO:0031594; GO:0005634; GO:0018991; GO:0036062; GO:0031647; GO:0050807; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; body morphogenesis; locomotion; negative regulation of MAPK cascade; neuromuscular junction; nucleus; oviposition; presynaptic periactive zone; regulation of protein stability; regulation of synapse organization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF08005;PF00415;PF00643;PF13639;,,,,,,,,,RPM1_CAEEL,Caenorhabditis elegans,"body morphogenesis [GO:0010171]; locomotion [GO:0040011]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of axon regeneration [GO:0048681]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of MAPK cascade [GO:0043409]; oviposition [GO:0018991]; positive regulation of synapse assembly [GO:0051965]; regulation of protein stability [GO:0031647]; regulation of synapse organization [GO:0050807]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129078_c0_seq2,498,35.1406,0.32717153,2,0,,1.00E-09,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp129081_c0_seq3,568,34.331,0.12085849,7,33,,2.00E-51,Q8BI99,Zinc finger protein 879,Zinc finger protein 879,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,5.00E-11,CHOYP_PRDM9.1.1,,,,,,,ZN879_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129084_c0_seq2,774,43.0233,0.74574514,11,11,,1.00E-52,Q80U56,Late secretory pathway protein AVL9 homolog,Late secretory pathway protein AVL9 homolog,GO:0016477; GO:0016021; GO:0055037,cell migration; integral to membrane; recycling endosome,PF09794;,9.00E-22,CHOYP_LOC591009.1.1,,,,,,,AVL9_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477] comp129087_c0_seq2,1031,41.2221,0.27051784,48,18,,4.00E-33,O95786,Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),GO:0005524; GO:0008026; GO:0039529; GO:0015629; GO:0005829; GO:0009597; GO:0003690; GO:0003725; GO:0045087; GO:0019048; GO:0032480; GO:0002230; GO:0032727; GO:0032728; GO:0051091; GO:0042993; GO:0045944; GO:0030334; GO:0034344; GO:0043330; GO:0032587; GO:0003727; GO:0005923; GO:0008270,ATP binding; ATP-dependent helicase activity; RIG-I signaling pathway; actin cytoskeleton; cytosol; detection of virus; double-stranded DNA binding; double-stranded RNA binding; innate immune response; modulation by virus of host morphology or physiology; negative regulation of type I interferon production; positive regulation of defense response to virus by host; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of cell migration; regulation of type III interferon production; response to exogenous dsRNA; ruffle membrane; single-stranded RNA binding; tight junction; zinc ion binding,PF16739;PF00270;PF00271;PF11648;,,,,,,,,,DDX58_HUMAN,Homo sapiens (Human),cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032] comp129088_c1_seq1,2889,44.1329,0.66133707,193,177,,1.00E-137,Q13873,Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II),Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II),GO:0005524; GO:0030509; GO:0016362; GO:0009952; GO:0060840; GO:0001974; GO:0009986; GO:0009267; GO:0005887; GO:0048286; GO:0001946; GO:0060836; GO:0001707; GO:0046872; GO:2000279; GO:0030308; GO:0003085; GO:0045906; GO:0030513; GO:0030501; GO:0010595; GO:0001938; GO:0045669; GO:0010862; GO:0014916; GO:0061298; GO:0006366; GO:0005024; GO:0048010; GO:0060841,"ATP binding; BMP signaling pathway; activin receptor activity, type II; anterior/posterior pattern specification; artery development; blood vessel remodeling; cell surface; cellular response to starvation; integral to plasma membrane; lung alveolus development; lymphangiogenesis; lymphatic endothelial cell differentiation; mesoderm formation; metal ion binding; negative regulation of DNA biosynthetic process; negative regulation of cell growth; negative regulation of systemic arterial blood pressure; negative regulation of vasoconstriction; positive regulation of BMP signaling pathway; positive regulation of bone mineralization; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of osteoblast differentiation; positive regulation of pathway-restricted SMAD protein phosphorylation; regulation of lung blood pressure; retina vasculature development in camera-type eye; transcription from RNA polymerase II promoter; transforming growth factor beta-activated receptor activity; vascular endothelial growth factor receptor signaling pathway; venous blood vessel development",PF01064;PF00069;,5.00E-64,CHOYP_WIT.1.1,,,,,,,BMPR2_HUMAN,Homo sapiens (Human),anterior/posterior pattern specification [GO:0009952]; artery development [GO:0060840]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; brain development [GO:0007420]; cellular response to BMP stimulus [GO:0071773]; cellular response to starvation [GO:0009267]; chondrocyte development [GO:0002063]; endochondral bone morphogenesis [GO:0060350]; endothelial cell apoptotic process [GO:0072577]; endothelial cell proliferation [GO:0001935]; limb development [GO:0060173]; lung alveolus development [GO:0048286]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; maternal placenta development [GO:0001893]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of chondrocyte proliferation [GO:1902731]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of systemic arterial blood pressure [GO:0003085]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell proliferation [GO:0042127]; regulation of lung blood pressure [GO:0014916]; retina vasculature development in camera-type eye [GO:0061298]; transcription from RNA polymerase II promoter [GO:0006366]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; venous blood vessel development [GO:0060841] comp129091_c0_seq1,435,44.3678,0.33094948,0,0,,,,,,,,,2.00E-13,CHOYP_SC6A5.3.7,,,,,,,,, comp129091_c0_seq11,867,42.7912,0.48778533,42,12,,2.00E-26,Q28001,Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Fragment),Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Fragment),GO:0032328; GO:0030054; GO:0015816; GO:0016021; GO:0015820; GO:0005328; GO:0015824; GO:0008021; GO:0030672,alanine transport; cell junction; glycine transport; integral to membrane; leucine transport; neurotransmitter:sodium symporter activity; proline transport; synaptic vesicle; synaptic vesicle membrane,PF00209;,4.00E-20,CHOYP_DGRI_GH22876.2.3,,,,,,,S6A17_BOVIN,Bos taurus (Bovine),alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824] comp129091_c0_seq12,2286,39.5888,0.41677264,0,0,,7.00E-122,A7Y2W8,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),GO:0005887; GO:0005328; GO:0005283,integral to plasma membrane; neurotransmitter:sodium symporter activity; sodium:amino acid symporter activity,PF00209;,6.00E-106,CHOYP_SC6A5.2.7,,,,,,,SC6A9_XENLA,Xenopus laevis (African clawed frog), comp129091_c0_seq2,2323,39.7762,0.41719584,0,0,,7.00E-120,A7Y2W8,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),GO:0005887; GO:0005328; GO:0005283,integral to plasma membrane; neurotransmitter:sodium symporter activity; sodium:amino acid symporter activity,PF00209;,6.00E-106,CHOYP_SC6A5.2.7,,,,,,,SC6A9_XENLA,Xenopus laevis (African clawed frog), comp129091_c0_seq3,398,43.7186,0.31971356,0,0,,2.00E-24,Q28001,Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Fragment),Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Fragment),GO:0032328; GO:0030054; GO:0015816; GO:0016021; GO:0015820; GO:0005328; GO:0015824; GO:0008021; GO:0030672,alanine transport; cell junction; glycine transport; integral to membrane; leucine transport; neurotransmitter:sodium symporter activity; proline transport; synaptic vesicle; synaptic vesicle membrane,PF00209;,2.00E-13,CHOYP_SC6A5.3.7,,,,,,,S6A17_BOVIN,Bos taurus (Bovine),alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824] comp129091_c0_seq5,1962,38.3282,0.44798186,8,0,,1.00E-17,Q9GZN6,Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16),Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16),GO:0016021; GO:0005622; GO:0005326; GO:0005328,integral to membrane; intracellular; neurotransmitter transporter activity; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,S6A16_HUMAN,Homo sapiens (Human),neurotransmitter transport [GO:0006836] comp129091_c0_seq8,280,45,0.43175967,0,0,,,,,,,,,2.00E-12,CHOYP_S620B.1.1,,,,,,,,, comp129092_c0_seq2,440,34.5455,0.07769596,8,11,,,,,,,,,,,7.00E-18,ruditapes_c10501,,,,,,, comp129093_c0_seq1,213,46.9484,0.25680566,5821,40810,,6.00E-42,P23398,Polyubiquitin [Cleaved into: Ubiquitin] (Fragment),Polyubiquitin [Cleaved into: Ubiquitin] (Fragment),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00240;,1.00E-57,CHOYP_UBIQP.2.13,2.00E-65,ruditapes2_lrc2999,,,,,UBIQP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp129096_c0_seq3,1481,44.497,0.4708721,72,42,,0,Q60544,Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250),Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250),GO:0005524; GO:0003677; GO:0006352; GO:0071339; GO:0004402; GO:0000080; GO:0045944; GO:0004674; GO:0005669,"ATP binding; DNA binding; DNA-dependent transcription, initiation; MLL1 complex; histone acetyltransferase activity; mitotic G1 phase; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; transcription factor TFIID complex",PF00439;PF12157;PF09247;,0,CHOYP_TAF1.1.1,,,,,,,TAF1_MESAU,Mesocricetus auratus (Golden hamster),"cell cycle [GO:0007049]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]" comp129096_c1_seq1,469,44.9893,0.21367619,9,7,,7.00E-25,Q8TEQ6,Gem-associated protein 5 (Gemin5),Gem-associated protein 5 (Gemin5),GO:0097504; GO:0005829; GO:0034660; GO:0016604; GO:0006461; GO:0017069; GO:0005681; GO:0000387,Gemini of coiled bodies; cytosol; ncRNA metabolic process; nuclear body; protein complex assembly; snRNA binding; spliceosomal complex; spliceosomal snRNP assembly,PF12894;PF00400;,,,,,,,,,GEMI5_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; protein complex assembly [GO:0006461]; spliceosomal snRNP assembly [GO:0000387]" comp129101_c1_seq1,1300,41.2308,0.60323154,0,0,,1.00E-24,Q9D0B0,"Serine/arginine-rich splicing factor 9 (Splicing factor, arginine/serine-rich 9)","Serine/arginine-rich splicing factor 9 (Splicing factor, arginine/serine-rich 9)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0005730; GO:0000166,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nucleolus; nucleotide binding",PF00076;,7.00E-96,CHOYP_LOC100367051.1.1,,,,,,,SRSF9_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" comp129101_c1_seq3,1658,38.9626,0.67368915,38,303,,5.00E-71,Q8VE97,"Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)","Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0016607; GO:0000166,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nuclear speck; nucleotide binding",PF00076;,5.00E-92,CHOYP_LOC100367051.1.1,,,,,,,SRSF4_MOUSE,Mus musculus (Mouse),"hematopoietic progenitor cell differentiation [GO:0002244]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" comp129101_c1_seq6,1923,42.4857,0.45875072,0,0,,1.00E-35,P26686,Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed),Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed),GO:0071013; GO:0003729; GO:0006376; GO:0007067; GO:0016607; GO:0000166; GO:0005700; GO:0071011; GO:0000381; GO:0035327,"catalytic step 2 spliceosome; mRNA binding; mRNA splice site selection; mitosis; nuclear speck; nucleotide binding; polytene chromosome; precatalytic spliceosome; regulation of alternative mRNA splicing, via spliceosome; transcriptionally active chromatin",PF00076;,2.00E-48,CHOYP_SRSF4.2.6,,,,,,,SRR55_DROME,Drosophila melanogaster (Fruit fly),"mitotic nuclear division [GO:0007067]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]" comp129101_c1_seq7,694,46.5418,0.85649506,8,51,,,,,,,,,2.00E-35,CHOYP_SRSF4.1.6,,,,,,,,, comp129101_c1_seq8,1613,39.9876,0.67011671,0,0,,1.00E-70,Q8VE97,"Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)","Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0016607; GO:0000166,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nuclear speck; nucleotide binding",PF00076;,,,,,,,,,SRSF4_MOUSE,Mus musculus (Mouse),"hematopoietic progenitor cell differentiation [GO:0002244]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" comp129101_c1_seq9,1255,42.7888,0.59394156,2,0,,9.00E-51,Q23121,"Probable splicing factor, arginine/serine-rich 1 (CeSRp75) (RNA-binding protein srp-5)","Probable splicing factor, arginine/serine-rich 1 (CeSRp75) (RNA-binding protein srp-5)",GO:0003723; GO:0030154; GO:0000398; GO:0007275; GO:0000166; GO:0005634; GO:0040009; GO:0007283,"RNA binding; cell differentiation; mRNA splicing, via spliceosome; multicellular organismal development; nucleotide binding; nucleus; regulation of growth rate; spermatogenesis",PF00076;,5.00E-59,CHOYP_RS3A.4.15,,,,,,,RSP1_CAEEL,Caenorhabditis elegans,"cell differentiation [GO:0030154]; mRNA splicing, via spliceosome [GO:0000398]; multicellular organism development [GO:0007275]; regulation of growth rate [GO:0040009]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]" comp129110_c0_seq1,1119,38.1591,0.65306175,634,2584,,7.00E-21,Q5U4Z8,"39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20)","39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20)",GO:0005739; GO:0019843; GO:0005840; GO:0003735; GO:0006412,mitochondrion; rRNA binding; ribosome; structural constituent of ribosome; translation,PF00453;,,,1.00E-20,ruditapes_c7379,,,,,RM20_XENLA,Xenopus laevis (African clawed frog),translation [GO:0006412] comp129114_c0_seq1,1180,36.8644,0.35017816,797,4,male>female,4.00E-80,Q9Y6J8,Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX),Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX),GO:0035556; GO:0004721,intracellular signal transduction; phosphoprotein phosphatase activity,PF00782;PF00581;,4.00E-130,CHOYP_NEMVEDRAFT_V1G86312.1.1,,,,,,,STYL1_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp129116_c1_seq2,1491,33.937,0.46805662,2,6,,,,,,,,,,,1.00E-20,ruditapes_c11080,,,,,,, comp129116_c1_seq4,1150,35.0435,0.53864573,8,0,,,,,,,,,,,4.00E-64,ruditapes2_c3057,,,,,,, comp129118_c0_seq1,1373,39.3299,0.40660075,46,304,,4.00E-134,Q8K339,"DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein)","DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein)",GO:0006310; GO:0006281; GO:0006260; GO:0003723; GO:0005737; GO:0003690; GO:0006397; GO:0046872; GO:0016363; GO:0006974,DNA recombination; DNA repair; DNA replication; RNA binding; cytoplasm; double-stranded DNA binding; mRNA processing; metal ion binding; nuclear matrix; response to DNA damage stimulus,PF10357;,4.00E-99,CHOYP_BRAFLDRAFT_114345.1.1,,,,,,,KIN17_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mRNA processing [GO:0006397] comp129130_c0_seq1,1116,46.4158,1.05130281,6,88,,3.00E-07,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp129131_c0_seq1,802,35.9102,0.39209045,352,1226,,1.00E-27,A4QND0,Ubiquitin-like protein 4A,Ubiquitin-like protein 4A,GO:0071818; GO:0071816; GO:0006810,BAT3 complex; tail-anchored membrane protein insertion into ER membrane; transport,PF00240;,,,9.00E-52,ruditapes_c15108,,,,,UBL4A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810] comp129133_c0_seq1,1815,37.3003,0.38834548,2096,7178,,1.00E-135,Q58DA0,26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10),26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10),GO:0022624; GO:0008540; GO:0006511,"proteasome accessory complex; proteasome regulatory particle, base subcomplex; ubiquitin-dependent protein catabolic process",PF02809;PF13519;,3.00E-115,CHOYP_LOC658092.2.2,7.00E-89,ruditapes_c7399,,,,,PSMD4_BOVIN,Bos taurus (Bovine),proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp129136_c0_seq1,907,35.3914,0.52885053,81,176,,2.00E-42,Q28FY0,Protein tilB homolog (Leucine-rich repeat-containing protein 6),Protein tilB homolog (Leucine-rich repeat-containing protein 6),GO:0005929; GO:0005737,cilium; cytoplasm,,5.00E-32,CHOYP_LOC586953.1.1,,,,,,,TILB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium movement [GO:0003341] comp129138_c0_seq1,672,45.0893,0.68961494,0,0,,3.00E-29,Q9JIR4,Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1),Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1),GO:0030054; GO:0006887; GO:0006886; GO:0060291; GO:0046872; GO:0006836; GO:0031632; GO:0042734,cell junction; exocytosis; intracellular protein transport; long-term synaptic potentiation; metal ion binding; neurotransmitter transport; positive regulation of synaptic vesicle fusion to presynaptic membrane; presynaptic membrane,PF00168;PF02318;PF00595;,3.00E-14,CHOYP_RIMS2.3.3,,,,,,,RIMS1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic potentiation [GO:0060291]; neurotransmitter transport [GO:0006836]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic vesicle fusion to presynaptic membrane [GO:0031632]; positive regulation of synaptic vesicle priming [GO:0010808] comp129138_c0_seq4,717,45.7462,0.62250367,0,0,,,,,,,,,3.00E-14,CHOYP_RIMS2.3.3,,,,,,,,, comp129138_c0_seq5,1700,45.7059,0.82961025,0,0,,1.00E-28,Q9JIR4,Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1),Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1),GO:0030054; GO:0006887; GO:0006886; GO:0060291; GO:0046872; GO:0006836; GO:0031632; GO:0042734,cell junction; exocytosis; intracellular protein transport; long-term synaptic potentiation; metal ion binding; neurotransmitter transport; positive regulation of synaptic vesicle fusion to presynaptic membrane; presynaptic membrane,PF00168;PF02318;PF00595;,,,,,,,,,RIMS1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic potentiation [GO:0060291]; neurotransmitter transport [GO:0006836]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic vesicle fusion to presynaptic membrane [GO:0031632]; positive regulation of synaptic vesicle priming [GO:0010808] comp129138_c1_seq1,354,43.7853,1.20872602,17,0,,,,,,,,,5.00E-15,CHOYP_RIMS2.2.3,,,,,,,,, comp129140_c0_seq1,819,38.4615,0.72759647,69,496,,1.00E-25,Q9DAT2,MRG/MORF4L-binding protein (MRG-binding protein),MRG/MORF4L-binding protein (MRG-binding protein),GO:0043189; GO:0016568; GO:0040008; GO:0006355; GO:0006351,"H4/H2A histone acetyltransferase complex; chromatin modification; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07904;,1.00E-21,CHOYP_LOC588659.1.1,2.00E-35,ruditapes_c26614,,,,,MRGBP_MOUSE,Mus musculus (Mouse),"histone acetylation [GO:0016573]; regulation of growth [GO:0040008]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp129146_c0_seq1,517,50.2901,0.30716434,26,8,,3.00E-07,Q9BVV6,Protein TALPID3,Protein TALPID3,GO:0005813; GO:0060271; GO:0005737; GO:0007224,centrosome; cilium morphogenesis; cytoplasm; smoothened signaling pathway,PF15324;,,,,,,,,,K0586_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of establishment of protein localization [GO:0070201]; smoothened signaling pathway [GO:0007224] comp129155_c0_seq1,3562,47.0522,0.65483903,211,2050,,0,A2VD00,Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta),Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta),GO:0016282; GO:0033290; GO:0005852; GO:0001732; GO:0001731; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation initiation complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity,PF01399;,0,CHOYP_MROH1.1.1,,,,,,,EIF3A_XENLA,Xenopus laevis (African clawed frog),formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] comp129155_c0_seq2,3610,47.313,0.68119228,26,910,,0,Q6PCR7,Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta),Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta),GO:0016282; GO:0033290; GO:0005852; GO:0001732; GO:0001731; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation initiation complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity,PF01399;,9.00E-24,CHOYP_BRAFLDRAFT_75590.1.1,,,,,,,EIF3A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] comp129155_c0_seq3,3538,46.9757,0.64460045,136,873,,0,Q6PCR7,Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta),Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta),GO:0016282; GO:0033290; GO:0005852; GO:0001732; GO:0001731; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation initiation complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity,PF01399;,0,CHOYP_MROH1.1.1,,,,,,,EIF3A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] comp129164_c0_seq1,1511,36.7306,0.56056377,6182,19668,,2.00E-101,P00125,"Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)","Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)",GO:0030054; GO:0009055; GO:0020037; GO:0016021; GO:0005506; GO:0005743; GO:0055114; GO:0070469,cell junction; electron carrier activity; heme binding; integral to membrane; iron ion binding; mitochondrial inner membrane; oxidation-reduction process; respiratory chain,PF02167;,1.00E-17,CHOYP_BRAFLDRAFT_214346.1.1,5.00E-58,ruditapes_c3439,,,,,CY1_BOVIN,Bos taurus (Bovine),oxidation-reduction process [GO:0055114] comp129167_c0_seq1,2083,32.6932,0.7824054,9298,20097,,1.00E-20,P00129,Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein),Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein),GO:0006122; GO:0005750,"mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial respiratory chain complex III",PF02271;,,,,,,,,,QCR7_BOVIN,Bos taurus (Bovine),"aerobic respiration [GO:0009060]; hydrogen ion transmembrane transport [GO:1902600]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]" comp129170_c0_seq1,1930,41.1399,1.25083068,46,331,,5.00E-81,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,5.00E-30,CHOYP_LOC100533356.3.6,6.00E-14,ruditapes_c18123,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp129173_c1_seq2,1002,41.4172,0.37430997,47,88,,2.00E-35,Q8K1A6,Coiled-coil and C2 domain-containing protein 1A (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1),Coiled-coil and C2 domain-containing protein 1A (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1),GO:0000978; GO:0001078; GO:0005737; GO:0005634; GO:0043123; GO:0004871,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cytoplasm; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity,PF00168;,3.00E-55,CHOYP_C2D1.1.1,,,,,,,C2D1A_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transcription, DNA-templated [GO:0006351]" comp129181_c0_seq1,323,44.582,0.12587533,13,24,,6.00E-29,Q29S00,Protein OSCP1,Protein OSCP1,GO:0009925; GO:0006810,basal plasma membrane; transport,PF10188;,3.00E-17,CHOYP_OSCP1.1.1,,,,,,,OSCP1_BOVIN,Bos taurus (Bovine),positive regulation of protein targeting to mitochondrion [GO:1903955]; transport [GO:0006810] comp129181_c3_seq1,341,48.0938,0.25568402,6,20,,3.00E-47,Q8BHW2,Protein OSCP1,Protein OSCP1,GO:0009925; GO:0006810,basal plasma membrane; transport,PF10188;,1.00E-59,CHOYP_TRIADDRAFT_50333.1.1,,,,,,,OSCP1_MOUSE,Mus musculus (Mouse),positive regulation of protein targeting to mitochondrion [GO:1903955]; transport [GO:0006810] comp129186_c0_seq1,1525,44.459,0.45553458,38,189,,3.00E-105,Q0VGK3,Glycerate kinase (EC 2.7.1.31),Glycerate kinase (EC 2.7.1.31),GO:0005524; GO:0005794; GO:0005737; GO:0008887; GO:0006468,ATP binding; Golgi apparatus; cytoplasm; glycerate kinase activity; protein phosphorylation,PF13660;PF05161;,,,,,,,,,GLCTK_RAT,Rattus norvegicus (Rat),protein phosphorylation [GO:0006468] comp129190_c0_seq1,1502,40.9454,0.84488392,217,2044,,1.00E-42,P27169,Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1),Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1),GO:0019439; GO:0004063; GO:0004064; GO:0005509; GO:0046395; GO:0008203; GO:0043231; GO:0046434; GO:0046470; GO:0005543; GO:0051099; GO:0010875; GO:0032411; GO:0042803; GO:0009605; GO:0009636; GO:0034366,aromatic compound catabolic process; aryldialkylphosphatase activity; arylesterase activity; calcium ion binding; carboxylic acid catabolic process; cholesterol metabolic process; intracellular membrane-bounded organelle; organophosphate catabolic process; phosphatidylcholine metabolic process; phospholipid binding; positive regulation of binding; positive regulation of cholesterol efflux; positive regulation of transporter activity; protein homodimerization activity; response to external stimulus; response to toxic substance; spherical high-density lipoprotein particle,PF01731;,,,,,,,,,PON1_HUMAN,Homo sapiens (Human),aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; cholesterol metabolic process [GO:0008203]; organophosphate catabolic process [GO:0046434]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of binding [GO:0051099]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transporter activity [GO:0032411]; response to external stimulus [GO:0009605]; response to fatty acid [GO:0070542]; response to fluoride [GO:1902617]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636] comp129192_c0_seq1,648,39.5062,0.73471873,1,0,,9.00E-07,Q6ZWJ8,Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1),Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_HUMAN,Homo sapiens (Human),positive regulation of BMP signaling pathway [GO:0030513] comp129195_c1_seq1,787,41.8043,0.43771364,0,0,,2.00E-19,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,,,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp129195_c1_seq3,1223,43.4178,0.5396829,0,0,,6.00E-26,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp129195_c1_seq4,1562,42.7657,0.49124481,16,12,,4.00E-48,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,,,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp129196_c0_seq1,906,34.4371,0.46324806,1137,7422,,1.00E-24,Q7TNS2,Mitochondrial inner membrane organizing system protein 1,MICOS complex subunit Mic10 (Mitochondrial inner membrane organizing system protein 1),GO:0016021; GO:0005743; GO:0005739,integral to membrane; mitochondrial inner membrane; mitochondrion,PF04418;,,,1.00E-19,ruditapes_lrc35190,,,,,MOS1_MOUSE,Mus musculus (Mouse), comp129201_c0_seq2,1063,40.0753,0.91591237,14,59,,2.00E-14,Q8N6G6,ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),GO:0008237; GO:0005578; GO:0008270,metallopeptidase activity; proteinaceous extracellular matrix; zinc ion binding,PF07679;PF08686;PF00090;,,,,,,,,,ATL1_HUMAN,Homo sapiens (Human),protein O-linked fucosylation [GO:0036066] comp129203_c1_seq1,1653,45.856,0.44032214,7,0,,9.00E-54,Q9NR09,Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),GO:0005794; GO:0006915; GO:0051301; GO:0004869; GO:0005768; GO:0060711; GO:0016020; GO:0005815; GO:0030496; GO:0007067; GO:0043066; GO:2001237; GO:0008284; GO:0006468; GO:0042127; GO:0032465; GO:0000922; GO:0060712; GO:0005802; GO:0004842,Golgi apparatus; apoptotic process; cell division; cysteine-type endopeptidase inhibitor activity; endosome; labyrinthine layer development; membrane; microtubule organizing center; midbody; mitosis; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; positive regulation of cell proliferation; protein phosphorylation; regulation of cell proliferation; regulation of cytokinesis; spindle pole; spongiotrophoblast layer development; trans-Golgi network; ubiquitin-protein ligase activity,PF00653;PF12356;PF00179;,,,,,,,,,BIRC6_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] comp129203_c1_seq3,1632,45.9559,0.44430937,2,0,,,,,,,,,5.00E-35,CHOYP_BIRC6.1.2,,,,,,,,, comp129206_c0_seq1,1289,41.505,0.96723596,33,496,,5.00E-128,Q29RU9,Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),GO:0033514; GO:0050031; GO:0005777; GO:0008115; GO:0046653,L-lysine catabolic process to acetyl-CoA via L-pipecolate; L-pipecolate oxidase activity; peroxisome; sarcosine oxidase activity; tetrahydrofolate metabolic process,PF01266;,2.00E-19,CHOYP_LOC100673983.1.1,1.00E-32,ruditapes2_c2779,,,,,SOX_BOVIN,Bos taurus (Bovine),L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; tetrahydrofolate metabolic process [GO:0046653] comp129208_c0_seq1,1255,44.8606,0.56372019,48,29,,2.00E-175,O94889,Kelch-like protein 18,Kelch-like protein 18,,,PF07707;PF00651;PF01344;,1.00E-167,CHOYP_LOC100370157.1.1,,,,,,,KLH18_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp129208_c0_seq2,576,44.6181,0.73775954,54,34,,1.00E-31,Q6DFU2,Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog),Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog),GO:0005737; GO:0005856; GO:0005634,cytoplasm; cytoskeleton; nucleus,PF07707;PF00651;PF01344;,,,,,,,,,NS1BP_XENLA,Xenopus laevis (African clawed frog), comp129208_c0_seq3,695,46.4748,0.51303644,4,0,,1.00E-08,Q9SVA0,F-box/kelch-repeat protein At4g39580,F-box/kelch-repeat protein At4g39580,,,PF00646;PF01344;,,,,,,,,,FK101_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp129210_c0_seq2,611,38.6252,1.04081911,15,39,,5.00E-39,B0BLZ5,Protein THEM6,Protein THEM6,GO:0005576,extracellular region,,,,,,,,,,THEM6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp129211_c0_seq1,1288,45.5745,0.51631708,4,0,,1.00E-34,Q9UIF8,Bromodomain adjacent to zinc finger domain protein 2B (hWALp4),Bromodomain adjacent to zinc finger domain protein 2B (hWALp4),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF01429;PF00628;PF15613;,,,,,,,,,BAZ2B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129211_c0_seq2,1304,47.1626,0.47671773,4,45,,2.00E-51,Q9DE13,Bromodomain adjacent to zinc finger domain protein 2B (Extracellular matrix protein F22),Bromodomain adjacent to zinc finger domain protein 2B (Extracellular matrix protein F22),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF01429;PF00628;PF15613;,6.00E-52,CHOYP_BRAFLDRAFT_122791.6.6,,,,,,,BAZ2B_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129212_c0_seq1,683,48.7555,0.42265284,3,0,,,,,,,,,1.00E-20,CHOYP_PG2IP.1.1,,,,,,,,, comp129212_c0_seq2,2201,42.299,0.40719346,21,84,,2.00E-164,Q9H720,PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog),PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog),GO:0006506; GO:0016021,GPI anchor biosynthetic process; integral to membrane,PF03372;,,,,,,,,,PG2IP_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506] comp129212_c0_seq3,1759,44.7413,0.39950205,0,0,,7.00E-160,Q9H720,PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog),PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog),GO:0006506; GO:0016021,GPI anchor biosynthetic process; integral to membrane,PF03372;,1.00E-99,CHOYP_PG2IP.1.1,,,,,,,PG2IP_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506] comp129214_c0_seq1,915,33.1148,0.53926339,409,2652,,2.00E-09,Q3MHJ5,"39S ribosomal protein L54, mitochondrial (L54mt) (MRP-L54)","39S ribosomal protein L54, mitochondrial (L54mt) (MRP-L54)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF08561;,,,5.00E-24,ruditapes2_c1444,,,,,RM54_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp129217_c0_seq1,1690,44.3787,0.32875228,2,0,,2.00E-66,P11533,Dystrophin,Dystrophin,GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0045211; GO:0042383; GO:0008270,calcium ion binding; cell junction; cytoplasm; cytoskeleton; postsynaptic membrane; sarcolemma; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;,,,,,,,,,DMD_CHICK,Gallus gallus (Chicken),muscle attachment [GO:0016203] comp129217_c0_seq2,1836,43.6275,0.34721834,7,24,,1.00E-59,P46939,Utrophin (Dystrophin-related protein 1) (DRP-1),Utrophin (Dystrophin-related protein 1) (DRP-1),GO:0003779; GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0016010; GO:0030175; GO:0006936; GO:0007517; GO:0031594; GO:0005634; GO:0005886; GO:0001954; GO:0045211; GO:0043234; GO:2000649; GO:0008270,actin binding; calcium ion binding; cell junction; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; filopodium; muscle contraction; muscle organ development; neuromuscular junction; nucleus; plasma membrane; positive regulation of cell-matrix adhesion; postsynaptic membrane; protein complex; regulation of sodium ion transmembrane transporter activity; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00569;,,,,,,,,,UTRO_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649] comp129217_c1_seq1,684,44.152,0.27068024,3,5,,5.00E-53,Q9H254,"Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)","Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)",GO:0016605; GO:0003779; GO:0051693; GO:0005912; GO:0007628; GO:0030506; GO:0007411; GO:0043203; GO:0043194; GO:0061337; GO:0070852; GO:0021952; GO:0045162; GO:0007016; GO:0005829; GO:0090002; GO:0009566; GO:0010459; GO:0033268; GO:0016363; GO:0033270; GO:0005543; GO:0005886; GO:0040018; GO:0033135; GO:0002028; GO:0007605; GO:0008091; GO:0030507; GO:0005200; GO:0019226; GO:0016192,PML body; actin binding; actin filament capping; adherens junction; adult walking behavior; ankyrin binding; axon guidance; axon hillock; axon initial segment; cardiac conduction; cell body fiber; central nervous system projection neuron axonogenesis; clustering of voltage-gated sodium channels; cytoskeletal anchoring at plasma membrane; cytosol; establishment of protein localization to plasma membrane; fertilization; negative regulation of heart rate; node of Ranvier; nuclear matrix; paranode region of axon; phospholipid binding; plasma membrane; positive regulation of multicellular organism growth; regulation of peptidyl-serine phosphorylation; regulation of sodium ion transport; sensory perception of sound; spectrin; spectrin binding; structural constituent of cytoskeleton; transmission of nerve impulse; vesicle-mediated transport,PF00307;PF00435;,1.00E-64,CHOYP_DLP.1.1,,,,,,,SPTN4_HUMAN,Homo sapiens (Human),actin filament capping [GO:0051693]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cardiac conduction [GO:0061337]; central nervous system projection neuron axonogenesis [GO:0021952]; clustering of voltage-gated sodium channels [GO:0045162]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization to plasma membrane [GO:0090002]; fertilization [GO:0009566]; MAPK cascade [GO:0000165]; negative regulation of heart rate [GO:0010459]; positive regulation of multicellular organism growth [GO:0040018]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of sodium ion transport [GO:0002028]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226]; vesicle-mediated transport [GO:0016192] comp129217_c1_seq2,588,44.7279,0.20444349,0,8,,9.00E-33,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp129218_c0_seq1,673,35.6612,0.37572378,16,54,,2.00E-33,A0JNB1,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129218_c1_seq1,980,32.3469,0.35299093,35,100,,3.00E-14,P08045,Zinc finger protein Xfin (Xenopus fingers protein) (Xfin),Zinc finger protein Xfin (Xenopus fingers protein) (Xfin),GO:0003723; GO:0005737; GO:0046872; GO:0006355,"RNA binding; cytoplasm; metal ion binding; regulation of transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,XFIN_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]" comp129218_c1_seq2,549,31.694,0.36725549,0,0,,7.00E-09,Q5R5N5,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,MYNN_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129220_c0_seq1,969,37.8741,0.72863927,3210,9895,,7.00E-21,Q95KV7,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic-interferon-induced mortality 19 protein) (GRIM-19) (NADH-ubiquinone oxidoreductase B16.6 subunit),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic-interferon-induced mortality 19 protein) (GRIM-19) (NADH-ubiquinone oxidoreductase B16.6 subunit),GO:0008137; GO:0030262; GO:0097190; GO:0016021; GO:0005746; GO:0030308; GO:0045892; GO:0005654,"NADH dehydrogenase (ubiquinone) activity; apoptotic nuclear changes; apoptotic signaling pathway; integral to membrane; mitochondrial respiratory chain; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; nucleoplasm",PF06212;,,,,,,,,,NDUAD_BOVIN,Bos taurus (Bovine),"apoptotic signaling pathway [GO:0097190]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription, DNA-templated [GO:0045892]" comp129221_c0_seq1,1265,46.3241,1.00419996,31,301,,5.00E-95,Q16TM5,Band 7 protein AAEL010189,Band 7 protein AAEL010189,GO:0016021,integral to membrane,PF01145;,1.00E-55,CHOYP_MEC2.2.4,3.00E-47,ruditapes_c11694,,,,,BND7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp129235_c3_seq1,977,46.7758,0.5457175,0,0,,9.00E-13,O19049,Heterogeneous nuclear ribonucleoprotein K (hnRNP K),Heterogeneous nuclear ribonucleoprotein K (hnRNP K),GO:0003677; GO:0003723; GO:0008380; GO:0030054; GO:0042995; GO:0005737; GO:0006397; GO:0005654; GO:0002102; GO:0006355; GO:0005681; GO:0006351,"DNA binding; RNA binding; RNA splicing; cell junction; cell projection; cytoplasm; mRNA processing; nucleoplasm; podosome; regulation of transcription, DNA-dependent; spliceosomal complex; transcription, DNA-dependent",PF00013;PF08067;,5.00E-52,CHOYP_LOC100905944.1.1,,,,,,,HNRPK_RABIT,Oryctolagus cuniculus (Rabbit),"mRNA processing [GO:0006397]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp129235_c3_seq2,1026,46.2963,0.58356473,2,6,,2.00E-69,P57721,Poly(rC)-binding protein 3 (Alpha-CP3),Poly(rC)-binding protein 3 (Alpha-CP3),GO:0003677; GO:0003723; GO:0005829; GO:0016071; GO:0005739; GO:0005634; GO:0030529,DNA binding; RNA binding; cytosol; mRNA metabolic process; mitochondrion; nucleus; ribonucleoprotein complex,PF00013;,3.00E-23,CHOYP_LOC658107.1.1,,,,,,,PCBP3_HUMAN,Homo sapiens (Human),mRNA metabolic process [GO:0016071] comp129236_c1_seq1,1180,39.4915,0.5738907,2,0,,1.00E-14,Q5ZMS4,Nuclear receptor coactivator 7,Nuclear receptor coactivator 7,GO:0016998; GO:0005634; GO:0006355; GO:0006351,"cell wall macromolecule catabolic process; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01476;PF07534;,6.00E-58,CHOYP_contig_015345,,,,,,,NCOA7_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129236_c1_seq3,1259,39.5552,0.5980266,4,0,,1.00E-43,Q08CX5,TBC1 domain family member 24,TBC1 domain family member 24,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF07534;,2.00E-51,CHOYP_LOC100120644.1.1,,,,,,,TBC24_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp129238_c0_seq2,1001,40.1598,0.85006448,55,49,,4.00E-56,Q7Z449,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0008219; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0097267; GO:0006805,aromatase activity; cell death; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; omega-hydroxylase P450 pathway; xenobiotic metabolic process,PF00067;,,,,,,,,,CP2U1_HUMAN,Homo sapiens (Human),omega-hydroxylase P450 pathway [GO:0097267] comp129239_c0_seq1,835,42.1557,1.17893387,25,197,,6.00E-72,Q16YG0,Cdc42 homolog,Cdc42 homolog,GO:0005525; GO:0005912; GO:0005622; GO:0045185; GO:0007275; GO:0005886; GO:0045860; GO:0007264,GTP binding; adherens junction; intracellular; maintenance of protein location; multicellular organismal development; plasma membrane; positive regulation of protein kinase activity; small GTPase mediated signal transduction,PF00071;,2.00E-43,CHOYP_CDC42.8.11,,,,,,,CDC42_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),maintenance of protein location [GO:0045185]; multicellular organism development [GO:0007275]; positive regulation of protein kinase activity [GO:0045860]; small GTPase mediated signal transduction [GO:0007264] comp129247_c0_seq1,1661,41.9627,0.56763261,1,0,,3.00E-82,Q9NEL2,Helicase ssl-1 (EC 3.6.4.-) (Swi/snf2-like protein 1),Helicase ssl-1 (EC 3.6.4.-) (Swi/snf2-like protein 1),GO:0005524; GO:0003677; GO:0016568; GO:0004386; GO:0007275; GO:0005634,ATP binding; DNA binding; chromatin modification; helicase activity; multicellular organismal development; nucleus,PF00271;PF07529;PF00176;,,,,,,,,,SSL1_CAEEL,Caenorhabditis elegans,chromatin modification [GO:0016568]; multicellular organism development [GO:0007275] comp129247_c0_seq2,3536,42.3925,0.49790676,884,2408,,0,O60264,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H),GO:0005524; GO:0016887; GO:0034080; GO:0003677; GO:0006352; GO:0016589; GO:0031213; GO:0003682; GO:0000183; GO:0005677; GO:0000793; GO:0006302; GO:0009790; GO:0004386; GO:0005730; GO:0005654; GO:0016584; GO:0045893; GO:0006357,"ATP binding; ATPase activity; CENP-A containing nucleosome assembly at centromere; DNA binding; DNA-dependent transcription, initiation; NURF complex; RSF complex; chromatin binding; chromatin silencing at rDNA; chromatin silencing complex; condensed chromosome; double-strand break repair; embryo development; helicase activity; nucleolus; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter",PF13892;PF09110;PF00271;PF09111;PF00176;,0,CHOYP_SMARCA5.1.1,,,9.00E-110,AM869433.p.cg.6,9,female gonad,SMCA5_HUMAN,Homo sapiens (Human),"ATP-dependent chromatin remodeling [GO:0043044]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair [GO:0006302]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]" comp129250_c0_seq1,907,38.1477,0.95323357,50,416,,5.00E-15,P0C7P0,"CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2)","CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2)",GO:0051537; GO:0046872; GO:0005739,"2 iron, 2 sulfur cluster binding; metal ion binding; mitochondrion",PF09360;,,,4.00E-19,ruditapes_c23250,,,,,CISD3_HUMAN,Homo sapiens (Human), comp129253_c0_seq1,1140,46.5789,0.55247985,21,24,,2.00E-45,P55266,Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37),Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37),GO:0003677; GO:0006382; GO:0005737; GO:0051607; GO:0003726; GO:0003725; GO:0031047; GO:0045087; GO:0006397; GO:0046872; GO:0044387; GO:0005730; GO:0045070; GO:0006355; GO:0035455; GO:0009615; GO:0044530; GO:0006351,"DNA binding; adenosine to inosine editing; cytoplasm; defense response to virus; double-stranded RNA adenosine deaminase activity; double-stranded RNA binding; gene silencing by RNA; innate immune response; mRNA processing; metal ion binding; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; positive regulation of viral genome replication; regulation of transcription, DNA-dependent; response to interferon-alpha; response to virus; supraspliceosomal complex; transcription, DNA-dependent",PF02137;PF00035;PF02295;,,,,,,,,,DSRAD_RAT,Rattus norvegicus (Rat),"adenosine to inosine editing [GO:0006382]; defense response to virus [GO:0051607]; gene silencing by RNA [GO:0031047]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of viral genome replication [GO:0045070]; regulation of transcription, DNA-templated [GO:0006355]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]" comp129253_c0_seq2,643,47.4339,0.52641669,0,0,,3.00E-27,P51400,Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase),Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase),GO:0006396; GO:0006382; GO:0003726; GO:0003725; GO:0016556; GO:0006397; GO:0046872; GO:0030336; GO:0008285; GO:0044387; GO:0005730; GO:0005654; GO:0045070; GO:0051726,RNA processing; adenosine to inosine editing; double-stranded RNA adenosine deaminase activity; double-stranded RNA binding; mRNA modification; mRNA processing; metal ion binding; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; nucleoplasm; positive regulation of viral genome replication; regulation of cell cycle,PF02137;PF00035;,2.00E-15,CHOYP_BRAFLDRAFT_124903.1.1,,,,,,,RED1_RAT,Rattus norvegicus (Rat),adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396] comp129255_c0_seq1,1321,43.5276,0.48023858,2,0,,5.00E-33,P30337,N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2),N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2),GO:0005096; GO:0048013; GO:0005622; GO:0035556; GO:0046872; GO:0008045; GO:0001565; GO:0050770,GTPase activator activity; ephrin receptor signaling pathway; intracellular; intracellular signal transduction; metal ion binding; motor neuron axon guidance; phorbol ester receptor activity; regulation of axonogenesis,PF00130;PF00620;,,,,,,,,,CHIN_RAT,Rattus norvegicus (Rat),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165] comp129255_c0_seq2,1415,44.0989,0.52369042,15,4,,1.00E-96,Q5ZMW5,Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Rho-type GTPase-activating protein 26),Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Rho-type GTPase-activating protein 26),GO:0005096; GO:0005737; GO:0005856; GO:0046847; GO:0005925; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; cytoskeleton; filopodium assembly; focal adhesion; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00169;PF00620;PF14604;,1.00E-87,CHOYP_LOC100749296.1.1,,,,,,,RHG26_CHICK,Gallus gallus (Chicken),actin cytoskeleton organization [GO:0030036]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp129255_c0_seq3,409,35.2078,0.81755225,16,0,,,,,,,,,1.00E-11,CHOYP_DSEC_GM22529.1.1,,,,,,,,, comp129257_c1_seq1,1213,36.6035,0.44739297,21,148,,3.00E-42,Q02338,"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase)","D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)",GO:0003858; GO:0060612; GO:0007420; GO:0044255; GO:0046951; GO:0046952; GO:0001889; GO:0005743; GO:0005759; GO:0005634; GO:0005543; GO:0046686; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0060416; GO:0032868; GO:0007584; GO:0042594; GO:0009636,3-hydroxybutyrate dehydrogenase activity; adipose tissue development; brain development; cellular lipid metabolic process; ketone body biosynthetic process; ketone body catabolic process; liver development; mitochondrial inner membrane; mitochondrial matrix; nucleus; phospholipid binding; response to cadmium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to growth hormone stimulus; response to insulin stimulus; response to nutrient; response to starvation; response to toxic substance,PF00106;,4.00E-16,CHOYP_RDH7.2.2,,,,,,,BDH_HUMAN,Homo sapiens (Human),adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636] comp129258_c0_seq1,1266,36.4929,0.99791905,57264,1698,,2.00E-08,P0CW97,Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),GO:0016021,integral to membrane,PF04749;,4.00E-23,CHOYP_LOC100891563.2.2,2.00E-36,ruditapes_c31240,,,,,PCR3_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp129262_c0_seq1,1858,34.5533,0.40089408,15,102,,2.00E-30,Q6DGV7,Mpv17-like protein 2,Mpv17-like protein 2,GO:0016021,integral to membrane,PF04117;,,,,,,,,,M17L2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129262_c0_seq2,1599,34.0213,0.37158484,0,6,,7.00E-20,Q54XX9,PXMP2/4 family protein 2,PXMP2/4 family protein 2,GO:0016021,integral to membrane,PF04117;,,,,,,,,,PX24B_DICDI,Dictyostelium discoideum (Slime mold), comp129263_c0_seq1,860,36.0465,0.3632763,0,0,,6.00E-08,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129263_c0_seq2,1397,37.4374,0.84757385,56,77,,8.00E-10,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129265_c0_seq1,770,41.1688,0.67523999,4461,21214,,1.00E-55,P62958,Histidine triad nucleotide-binding protein 1 (EC 3.-.-.-) (17 kDa inhibitor of protein kinase C) (Adenosine 5'-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1),Histidine triad nucleotide-binding protein 1 (EC 3.-.-.-) (17 kDa inhibitor of protein kinase C) (Adenosine 5'-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1),GO:0005737; GO:0000118; GO:0016787; GO:0072332; GO:0000166; GO:0005886; GO:0009154; GO:0006355; GO:0006351,"cytoplasm; histone deacetylase complex; hydrolase activity; intrinsic apoptotic signaling pathway by p53 class mediator; nucleotide binding; plasma membrane; purine ribonucleotide catabolic process; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01230;,3.00E-34,CHOYP_HINT1.1.1,3.00E-58,ruditapes_c5346,,,,,HINT1_BOVIN,Bos taurus (Bovine),"intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129267_c0_seq1,1929,41.1612,0.46963161,10313,134288,,0,O93477,Adenosylhomocysteinase B (AdoHcyase B) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase B),Adenosylhomocysteinase B (AdoHcyase B) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase B),GO:0004013; GO:0006730,adenosylhomocysteinase activity; one-carbon metabolic process,PF05221;PF00670;,0,CHOYP_SAHHA.1.1,0,ruditapes2_lrc3157,,,,,SAHHB_XENLA,Xenopus laevis (African clawed frog),one-carbon metabolic process [GO:0006730] comp129268_c0_seq2,434,36.8664,0.42069856,10,31,,1.00E-06,Q60821,Zinc finger and BTB domain-containing protein 17 (LP-1) (Polyomavirus late initiator promoter-binding protein) (Zinc finger protein 100) (Zfp-100) (Zinc finger protein 151) (Zinc finger protein Z13),Zinc finger and BTB domain-containing protein 17 (LP-1) (Polyomavirus late initiator promoter-binding protein) (Zinc finger protein 100) (Zfp-100) (Zinc finger protein 151) (Zinc finger protein Z13),GO:0003677; GO:0007398; GO:0001702; GO:0046872; GO:0005634; GO:0045893; GO:0003700; GO:0006351,"DNA binding; ectoderm development; gastrulation with mouth forming second; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT17_MOUSE,Mus musculus (Mouse),"ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitophagy [GO:1903146]; transcription, DNA-templated [GO:0006351]" comp129268_c2_seq1,1195,39.4979,0.58346978,66,112,,6.00E-09,Q66H30,Gypsy retrotransposon integrase-like protein 1 (GIN-1),Gypsy retrotransposon integrase-like protein 1 (GIN-1),GO:0015074; GO:0003676,DNA integration; nucleic acid binding,,,,,,,,,,GIN1_RAT,Rattus norvegicus (Rat),DNA integration [GO:0015074] comp129269_c0_seq1,589,37.3514,0.64432309,1385,3449,,2.00E-17,Q9P0M9,"39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27)","39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF01016;,7.00E-22,CHOYP_LOC101159300.1.1,7.00E-26,ruditapes2_c261,,,,,RM27_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412] comp129271_c0_seq2,1942,44.3872,0.96378994,114,109,,1.00E-20,C9J069,Uncharacterized protein C9orf172,Uncharacterized protein C9orf172,,,,,,,,,,,,CI172_HUMAN,Homo sapiens (Human), comp129271_c0_seq3,483,42.8571,1.12979009,10,21,,3.00E-14,A2AJA9,Uncharacterized protein C9orf172 homolog,Uncharacterized protein C9orf172 homolog,,,,,,,,,,,,CI172_MOUSE,Mus musculus (Mouse), comp129272_c0_seq2,733,35.7435,0.39412996,5,6,,2.00E-14,Q5REK7,UPF0693 protein C10orf32 homolog,UPF0693 protein C10orf32 homolog,,,PF16088;,2.00E-18,CHOYP_CJ032.1.1,5.00E-61,ruditapes2_c3066,,,,,CJ032_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp129274_c0_seq1,439,43.508,1.02804272,0,79,,2.00E-16,F7E235,Failed axon connections homolog,Failed axon connections homolog,GO:0016021,integral to membrane,PF17171;PF17172;,,,,,,,,,FAXC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp129274_c1_seq1,681,41.4097,0.93829502,8,281,,4.00E-18,Q3UMF9,Failed axon connections homolog,Failed axon connections homolog,GO:0016021,integral to membrane,PF17171;PF17172;,,,,,,,,,FAXC_MOUSE,Mus musculus (Mouse), comp129282_c0_seq1,222,41.4414,0.31631848,6,19,,1.00E-08,P55879,Zinc finger protein GLI2 (Fragment),Zinc finger protein GLI2 (Fragment),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0045893; GO:0003700; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,,,,,,,,,GLI2_CHICK,Gallus gallus (Chicken),"multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp129296_c0_seq1,1120,44.9107,0.62137771,50,167,,1.00E-57,Q8TDM6,Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),GO:0008013; GO:0005913; GO:0016337; GO:0005737; GO:0008092; GO:0035556; GO:0008285; GO:0005886; GO:0030159; GO:0042981,beta-catenin binding; cell-cell adherens junction; cell-cell adhesion; cytoplasm; cytoskeletal protein binding; intracellular signal transduction; negative regulation of cell proliferation; plasma membrane; receptor signaling complex scaffold activity; regulation of apoptotic process,PF00625;PF00595;PF04822;,,,,,,,,,DLG5_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186] comp129299_c0_seq1,1070,39.7196,0.48571471,28,338,,2.00E-48,O08848,60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2),60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2),GO:0003723; GO:0060271; GO:0005737; GO:0046872; GO:0030529,RNA binding; cilium morphogenesis; cytoplasm; metal ion binding; ribonucleoprotein complex,PF05731;,,,,,,,,,RO60_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224] comp129301_c1_seq1,787,39.3901,1.03228699,6,120,,6.00E-70,P91924,ADP-ribosylation factor,ADP-ribosylation factor,GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,8.00E-23,CHOYP_ARF2.3.3,1.00E-17,ruditapes_c19850,,,,,ARF_DUGJA,Dugesia japonica (Planarian),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp129303_c1_seq1,875,39.7714,0.89935537,22,136,,4.00E-46,Q91755,"Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)","Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)",GO:0030054; GO:0005234; GO:0016021; GO:0004970; GO:0035235; GO:0045211,cell junction; extracellular-glutamate-gated ion channel activity; integral to membrane; ionotropic glutamate receptor activity; ionotropic glutamate receptor signaling pathway; postsynaptic membrane,PF00060;,,,,,,,,,GRIK2_XENLA,Xenopus laevis (African clawed frog), comp129306_c0_seq1,1007,44.6872,0.31867881,35,9,,3.00E-28,Q5PQ35,E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),GO:0031410; GO:0006897; GO:0005783; GO:0005789; GO:0010008; GO:0016021; GO:0005765; GO:0004842; GO:0008270,cytoplasmic vesicle; endocytosis; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; integral to membrane; lysosomal membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,2.00E-11,CHOYP_MARCH3.1.1,,,,,,,MARH2_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897]; protein ubiquitination [GO:0016567] comp129314_c2_seq1,388,37.6289,0.36670681,3,25,,1.00E-38,Q02386,Zinc finger protein 45 (BRC1744) (Zinc finger protein 13) (Zinc finger protein KOX5),Zinc finger protein 45 (BRC1744) (Zinc finger protein 13) (Zinc finger protein KOX5),GO:0003677; GO:0046872; GO:0007275; GO:0005654; GO:0003700; GO:0006367,DNA binding; metal ion binding; multicellular organismal development; nucleoplasm; sequence-specific DNA binding transcription factor activity; transcription initiation from RNA polymerase II promoter,PF01352;PF00096;,,,,,,,,,ZNF45_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp129314_c3_seq1,338,35.2071,0.67034485,3,13,,1.00E-06,P33749,Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4),Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4),GO:0000982; GO:0001324; GO:0006338; GO:0000987; GO:0005829; GO:0046872; GO:0005634; GO:0061401; GO:0061402; GO:0061422; GO:0061412; GO:0061395; GO:0061410; GO:0061409; GO:0061406; GO:0061408; GO:0061407; GO:0061405; GO:0061404; GO:0061403; GO:0097236; GO:0061434; GO:0001302,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; age-dependent response to oxidative stress involved in chronological cell aging; chromatin remodeling; core promoter proximal region sequence-specific DNA binding; cytosol; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment; positive regulation of transcription from RNA polymerase II promoter in response to acidity; positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; positive regulation of transcription from RNA polymerase II promoter in response to ethanol; positive regulation of transcription from RNA polymerase II promoter in response to freezing; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation; positive regulation of transcription from RNA polymerase II promoter in response to heat stress; positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide; positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure; positive regulation of transcription from RNA polymerase II promoter in response to increased salt; positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction; replicative cell aging,PF00096;,,,,,,,,,MSN4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; cellular response to acidic pH [GO:0071468]; chromatin remodeling [GO:0006338]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [GO:0061401]; positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [GO:0061422]; positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [GO:0061412]; positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [GO:0061395]; positive regulation of transcription from RNA polymerase II promoter in response to cold [GO:0061411]; positive regulation of transcription from RNA polymerase II promoter in response to ethanol [GO:0061410]; positive regulation of transcription from RNA polymerase II promoter in response to freezing [GO:0061409]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [GO:0061407]; positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [GO:0061405]; positive regulation of transcription from RNA polymerase II promoter in response to increased salt [GO:0061404]; positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [GO:0061403]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [GO:0061434]; replicative cell aging [GO:0001302]; transcription, DNA-templated [GO:0006351]" comp129317_c0_seq1,271,29.8893,1.33171948,23,41,,,,,,,,,,,1.00E-12,ruditapes_c20166,,,,,,, comp129321_c0_seq1,1105,38.914,0.40848194,21,49,,1.00E-32,Q9JKC7,AP-4 complex subunit mu-1 (AP-4 adapter complex mu subunit) (Adapter-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4),AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4),GO:0005794; GO:0006895; GO:0030131; GO:0005905; GO:0006886; GO:0005802,Golgi apparatus; Golgi to endosome transport; clathrin adaptor complex; coated pit; intracellular protein transport; trans-Golgi network,PF00928;,,,,,,,,,AP4M1_MOUSE,Mus musculus (Mouse),Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp129323_c0_seq1,1747,41.4425,0.55307723,2633,11311,,0,Q641Y2,"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)","NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)",GO:0051539; GO:0051287; GO:0008137; GO:0046872; GO:0005747; GO:0048038; GO:0006979,"4 iron, 4 sulfur cluster binding; NAD binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; mitochondrial respiratory chain complex I; quinone binding; response to oxidative stress",PF00346;,0,CHOYP_LOC732900.1.1,3.00E-156,ruditapes_c18768,,,,,NDUS2_RAT,Rattus norvegicus (Rat),response to oxidative stress [GO:0006979] comp129328_c0_seq1,706,38.102,0.62991551,342,1126,,2.00E-38,Q9VFJ2,"39S ribosomal protein L11, mitochondrial (L11mt) (MRP-L11)","39S ribosomal protein L11, mitochondrial (L11mt) (MRP-L11)",GO:0031047; GO:0005762; GO:0006417; GO:0003735; GO:0006412,gene silencing by RNA; mitochondrial large ribosomal subunit; regulation of translation; structural constituent of ribosome; translation,PF00298;PF03946;,,,1.00E-49,ruditapes2_c504,,,,,RM11_DROME,Drosophila melanogaster (Fruit fly),gene silencing by RNA [GO:0031047]; regulation of translation [GO:0006417]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp129332_c1_seq1,1434,37.099,1.10416127,0,186,,2.00E-78,Q6NVP8,"Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)","Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)",GO:0032580; GO:0036071; GO:0008424; GO:0016021; GO:0033578,Golgi cisterna membrane; N-glycan fucosylation; glycoprotein 6-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation in Golgi,PF14604;,,,,,,,,,FUT8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] comp129343_c0_seq2,1131,39.5225,0.45374414,37,59,,3.00E-114,Q3UM45,Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),GO:0005634,nucleus,,2.00E-50,CHOYP_PPP1R7.1.1,,,,,,,PP1R7_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307] comp129343_c0_seq5,271,37.2694,0.76837204,0,0,,1.00E-18,Q3UM45,Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),GO:0005634,nucleus,,,,,,,,,,PP1R7_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307] comp129344_c0_seq2,481,40.3326,1.02991898,23,24,,2.00E-43,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,6.00E-28,CHOYP_RN213.6.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp129345_c0_seq1,2063,37.5667,0.37180762,2546,19834,,2.00E-117,O00303,Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47),Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47),GO:0008234; GO:0005829; GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006508; GO:0006446; GO:0003743,cysteine-type peptidase activity; cytosol; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; proteolysis; regulation of translational initiation; translation initiation factor activity,PF01398;PF13012;,6.00E-86,CHOYP_NFRKB.1.1,0,ruditapes2_c2079,,,,,EIF3F_HUMAN,Homo sapiens (Human),formation of translation preinitiation complex [GO:0001731]; IRES-dependent viral translational initiation [GO:0075522]; protein deubiquitination [GO:0016579]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp129352_c0_seq1,1881,48.3785,0.44630624,69,28,,7.00E-120,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,6.00E-35,CHOYP_VP13D.2.3,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp129354_c0_seq1,637,38.7755,0.42262955,54,142,,2.00E-41,B0BLT0,Zinc finger protein 593,Zinc finger protein 593,GO:0046872,metal ion binding,PF12171;,8.00E-41,CHOYP_LOC592435.1.1,3.00E-81,ruditapes2_c224,,,,,ZN593_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp129369_c1_seq1,1167,41.7309,0.23691701,92,364,,5.00E-37,Q9FYP9,Importin subunit alpha-2,Importin subunit alpha-2,GO:0005634; GO:0048471; GO:0006606; GO:0008565,nucleus; perinuclear region of cytoplasm; protein import into nucleus; protein transporter activity,PF00514;,,,,,,,,,IMA2_ORYSJ,Oryza sativa subsp. japonica (Rice),NLS-bearing protein import into nucleus [GO:0006607] comp129369_c1_seq2,400,42.5,0.05550208,2,0,,,,,,,,,1.00E-11,CHOYP_IMA2.1.2,,,,,,,,, comp129372_c0_seq2,1183,40.5748,0.37165205,19,68,,2.00E-07,Q8C1C8,Paraneoplastic antigen Ma1 homolog,Paraneoplastic antigen Ma1 homolog,GO:0005737; GO:0005925; GO:0002437; GO:0005730,cytoplasm; focal adhesion; inflammatory response to antigenic stimulus; nucleolus,PF14893;,,,,,,,,,PNMA1_MOUSE,Mus musculus (Mouse),inflammatory response to antigenic stimulus [GO:0002437] comp129374_c0_seq3,400,42.5,0.29377473,5,0,,,,,,,,,3.00E-12,CHOYP_LOC100123553.1.1,,,,,,,,, comp129379_c0_seq2,1425,42.5263,0.47359162,63,132,,2.00E-07,O94889,Kelch-like protein 18,Kelch-like protein 18,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH18_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp129381_c0_seq2,1909,44.8402,0.6478687,47,10,,2.00E-123,P42694,Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein),Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein),GO:0005524; GO:0004386; GO:0046872; GO:0005634,ATP binding; helicase activity; metal ion binding; nucleus,PF00642;,8.00E-110,CHOYP_BRAFLDRAFT_90929.1.1,,,,,,,HELZ_HUMAN,Homo sapiens (Human), comp129381_c1_seq3,1066,44.9343,0.50494313,0,9,,2.00E-24,Q9UGR2,Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN),Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN),GO:0046872; GO:0019048; GO:0005634,metal ion binding; modulation by virus of host morphology or physiology; nucleus,PF13181;PF00642;,3.00E-54,CHOYP_BRAFLDRAFT_90929.1.1,,,,,,,Z3H7B_HUMAN,Homo sapiens (Human),viral process [GO:0016032] comp129381_c1_seq4,1109,46.1677,0.49310702,14,0,,6.00E-25,Q9UGR2,Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN),Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN),GO:0046872; GO:0019048; GO:0005634,metal ion binding; modulation by virus of host morphology or physiology; nucleus,PF13181;PF00642;,,,,,,,,,Z3H7B_HUMAN,Homo sapiens (Human),viral process [GO:0016032] comp129381_c3_seq1,631,44.691,0.4209027,25,13,,8.00E-28,P42694,Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein),Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein),GO:0005524; GO:0004386; GO:0046872; GO:0005634,ATP binding; helicase activity; metal ion binding; nucleus,PF00642;,6.00E-23,CHOYP_HELZ.1.2,,,,,,,HELZ_HUMAN,Homo sapiens (Human), comp129382_c0_seq1,385,41.2987,0.92227446,1,0,,2.00E-19,Q9VCX1,Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco),Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco),GO:0007186; GO:0005092; GO:0005096; GO:0045179; GO:0016324; GO:0055059; GO:0008105; GO:0032291; GO:0007049; GO:0030866; GO:0007303; GO:0050832; GO:0008069; GO:0000578; GO:0014045; GO:0060857; GO:0003015; GO:0007310; GO:0005886; GO:0005057; GO:0008277; GO:0009786; GO:0009408; GO:0006979; GO:0042594; GO:0019991; GO:0038032; GO:0007419,"G-protein coupled receptor signaling pathway; GDP-dissociation inhibitor activity; GTPase activator activity; apical cortex; apical plasma membrane; asymmetric neuroblast division; asymmetric protein localization; axon ensheathment in central nervous system; cell cycle; cortical actin cytoskeleton organization; cytoplasmic transport, nurse cell to oocyte; defense response to fungus; dorsal/ventral axis specification, ovarian follicular epithelium; embryonic axis specification; establishment of endothelial blood-brain barrier; establishment of glial blood-brain barrier; heart process; oocyte dorsal/ventral axis specification; plasma membrane; receptor signaling protein activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of asymmetric cell division; response to heat; response to oxidative stress; response to starvation; septate junction assembly; termination of G-protein coupled receptor signaling pathway; ventral cord development",PF00595;PF02196;PF00615;,,,,,,,,,RGS_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization [GO:0008105]; axon ensheathment in central nervous system [GO:0032291]; cell cycle [GO:0007049]; cortical actin cytoskeleton organization [GO:0030866]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; defense response to fungus [GO:0050832]; dorsal/ventral axis specification, ovarian follicular epithelium [GO:0008069]; embryonic axis specification [GO:0000578]; establishment of endothelial blood-brain barrier [GO:0014045]; establishment of glial blood-brain barrier [GO:0060857]; glial cell differentiation [GO:0010001]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; oocyte dorsal/ventral axis specification [GO:0007310]; regulation of asymmetric cell division [GO:0009786]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to starvation [GO:0042594]; septate junction assembly [GO:0019991]; ventral cord development [GO:0007419]" comp129382_c0_seq2,865,44.3931,0.80580294,6,144,,2.00E-21,Q8CGE9,Regulator of G-protein signaling 12 (RGS12),Regulator of G-protein signaling 12 (RGS12),GO:0005096; GO:0005737; GO:0005634; GO:0005886; GO:0005057; GO:0038032,GTPase activator activity; cytoplasm; nucleus; plasma membrane; receptor signaling protein activity; termination of G-protein coupled receptor signaling pathway,PF02188;PF00595;PF02196;PF00615;,1.00E-15,CHOYP_LOC100889318.1.1,,,,,,,RGS12_MOUSE,Mus musculus (Mouse),termination of G-protein coupled receptor signaling pathway [GO:0038032] comp129386_c0_seq1,1101,36.3306,0.36045722,86,948,,7.00E-45,O60232,Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27),Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27),GO:0051301; GO:0007067,cell division; mitosis,PF06677;,1.00E-29,CHOYP_SSSCA1.1.2,,,,,,,SSA27_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp129397_c0_seq1,899,39.7108,0.29154555,95,850,,6.00E-49,Q5RA17,Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog),Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog),GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;PF12923;,1.00E-13,CHOYP_LOC100691983.1.1,2.00E-60,ruditapes2_c2107,,,,,RRP7A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp129412_c0_seq5,428,41.1215,0.88682655,0,8,,3.00E-27,Q2KN96,Cytospin-A (SPECC1-like protein) (Sperm antigen with calponin homology and coiled-coil domains 1-like),Cytospin-A (SPECC1-like protein) (Sperm antigen with calponin homology and coiled-coil domains 1-like),GO:0007049; GO:0051301; GO:0005737; GO:0005921; GO:0005819,cell cycle; cell division; cytoplasm; gap junction; spindle,PF00307;,,,,,,,,,CYTSA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; cell division [GO:0051301] comp129412_c0_seq6,531,43.5028,0.79760403,0,0,,6.00E-42,Q99LM3,Smoothelin-like protein 1 (Calponin homology-associated smooth muscle protein) (CHASM),Smoothelin-like protein 1 (Calponin homology-associated smooth muscle protein) (CHASM),GO:0031674; GO:0031430; GO:0048644; GO:0017020; GO:0045908; GO:0005634; GO:0018105; GO:0045907; GO:0004864; GO:0014823; GO:0042493,I band; M band; muscle organ morphogenesis; myosin phosphatase regulator activity; negative regulation of vasodilation; nucleus; peptidyl-serine phosphorylation; positive regulation of vasoconstriction; protein phosphatase inhibitor activity; response to activity; response to drug,PF00307;,4.00E-49,CHOYP_CG34417.2.2,,,,,,,SMTL1_MOUSE,Mus musculus (Mouse),"muscle organ morphogenesis [GO:0048644]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vasodilation [GO:0045908]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]" comp129416_c1_seq1,437,44.8513,0.59592149,19,10,,3.00E-37,P97412,Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog),Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog),GO:0002456; GO:0007596; GO:0005829; GO:0042742; GO:0042832; GO:0051607; GO:0030595; GO:0007040; GO:0033364; GO:0032438; GO:0007017; GO:0002446; GO:0055091; GO:0006644; GO:0032816; GO:0042493; GO:0033299,T cell mediated immunity; blood coagulation; cytosol; defense response to bacterium; defense response to protozoan; defense response to virus; leukocyte chemotaxis; lysosome organization; mast cell secretory granule organization; melanosome organization; microtubule-based process; neutrophil mediated immunity; phospholipid homeostasis; phospholipid metabolic process; positive regulation of natural killer cell activation; response to drug; secretion of lysosomal enzymes,PF02138;PF14844;PF00400;,9.00E-32,CHOYP_BRAFLDRAFT_126843.1.1,,,,,,,LYST_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; microtubule-based process [GO:0007017]; natural killer cell mediated cytotoxicity [GO:0042267]; neutrophil mediated immunity [GO:0002446]; phospholipid homeostasis [GO:0055091]; phospholipid metabolic process [GO:0006644]; pigmentation [GO:0043473]; pigment granule organization [GO:0048753]; positive regulation of natural killer cell activation [GO:0032816]; response to drug [GO:0042493]; secretion of lysosomal enzymes [GO:0033299]; T cell mediated immunity [GO:0002456] comp129416_c2_seq1,1052,44.8669,0.32149814,45,47,,,,,,,,,,,1.00E-13,ruditapes_c8960,,,,,,, comp129422_c1_seq2,1728,32.6389,0.52529925,73,377,,1.00E-44,Q4VBD9,GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GO:0001658; GO:0005737; GO:0046872; GO:0000122; GO:0005730; GO:0005634; GO:0043565; GO:0006351,"branching involved in ureteric bud morphogenesis; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,GZF1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp129424_c0_seq2,933,33.9764,1.15262871,20,0,,4.00E-10,P02637,Sarcoplasmic calcium-binding protein (SCP),Sarcoplasmic calcium-binding protein (SCP),GO:0005509,calcium ion binding,,,,,,,,,,SCP_MIZYE,Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis), comp129429_c1_seq2,956,38.3891,0.85294211,63,27,,,,,,,,,,,1.00E-19,ruditapes2_c2246,,,,,,, comp129445_c0_seq2,375,31.7333,0.53288361,3,15,,6.00E-10,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,3.00E-17,CHOYP_LOC100536520.4.4,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp129449_c0_seq1,1378,45.1379,0.95846394,123,177,,6.00E-20,P54842,Transcription factor MafB (Maf-B) (Transcription factor Maf-1) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B),Transcription factor MafB (Maf-B) (Transcription factor Maf-1) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B),GO:0035284; GO:0042472; GO:0045647; GO:0005634; GO:0045944; GO:0007585; GO:0021571; GO:0021572; GO:0007379; GO:0043565; GO:0003700; GO:0005667; GO:0006351,"brain segmentation; inner ear morphogenesis; negative regulation of erythrocyte differentiation; nucleus; positive regulation of transcription from RNA polymerase II promoter; respiratory gaseous exchange; rhombomere 5 development; rhombomere 6 development; segment specification; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF03131;PF08383;,2.00E-13,CHOYP_LOC100699096.1.1,,,,,,,MAFB_RAT,Rattus norvegicus (Rat),brain segmentation [GO:0035284]; inner ear morphogenesis [GO:0042472]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of osteoclast differentiation [GO:0045671]; nervous system development [GO:0007399]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; respiratory gaseous exchange [GO:0007585]; rhombomere 5 development [GO:0021571]; rhombomere 6 development [GO:0021572]; segment specification [GO:0007379]; T cell differentiation in thymus [GO:0033077]; thymus development [GO:0048538] comp12944_c0_seq1,332,42.4699,0.41111484,3,2,,8.00E-23,Q76IC6,Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23),Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,3.00E-11,CHOYP_LOC100549654.1.1,,,,,,,ZDH23_RAT,Rattus norvegicus (Rat),protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345] comp129450_c1_seq1,989,34.277,0.42386229,186,673,,3.00E-39,Q9UBK9,Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein),Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein),GO:0001106; GO:0048487; GO:0005813; GO:0051297; GO:0003682; GO:0005737; GO:0008017; GO:0047497; GO:0005634; GO:0016272; GO:0006457,RNA polymerase II transcription corepressor activity; beta-tubulin binding; centrosome; centrosome organization; chromatin binding; cytoplasm; microtubule binding; mitochondrion transport along microtubule; nucleus; prefoldin complex; protein folding,PF02996;,8.00E-24,CHOYP_UXT.1.1,,,,,,,UXT_HUMAN,Homo sapiens (Human),"centrosome organization [GO:0051297]; microtubule cytoskeleton organization [GO:0000226]; mitochondrion transport along microtubule [GO:0047497]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp129453_c2_seq2,1949,45.7671,0.24858885,82,22,,5.00E-167,Q9NU22,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0016887; GO:0005730; GO:0005634; GO:0006461; GO:0051082,ATP binding; ATPase activity; nucleolus; nucleus; protein complex assembly; unfolded protein binding,PF07728;,3.00E-14,CHOYP_MDN1.5.8,,,,,,,MDN1_HUMAN,Homo sapiens (Human),protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027] comp129453_c2_seq3,1174,44.0375,0.19490032,0,0,,6.00E-90,Q9NU22,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0016887; GO:0005730; GO:0005634; GO:0006461; GO:0051082,ATP binding; ATPase activity; nucleolus; nucleus; protein complex assembly; unfolded protein binding,PF07728;,,,,,,,,,MDN1_HUMAN,Homo sapiens (Human),protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027] comp129453_c4_seq1,247,44.1296,0.08557766,25,0,,,,,,,,,9.00E-22,CHOYP_MDN1.5.8,,,,,,,,, comp129457_c1_seq1,1928,44.4502,0.39988882,86,557,,6.00E-81,Q8CF89,TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1),TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1),GO:0000185; GO:0003824; GO:0003007; GO:0001701; GO:0019209; GO:0030324; GO:0008152; GO:0007179,activation of MAPKKK activity; catalytic activity; heart morphogenesis; in utero embryonic development; kinase activator activity; lung development; metabolic process; transforming growth factor beta receptor signaling pathway,PF00481;,3.00E-39,CHOYP_BRAFLDRAFT_259980.1.1,,,,,,,TAB1_MOUSE,Mus musculus (Mouse),activation of MAPKKK activity [GO:0000185]; aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp129459_c0_seq1,995,39.0955,0.79961545,6,200,,2.00E-46,Q6ZN57,Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751),Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZFP2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129465_c0_seq1,681,41.4097,0.6288948,21,286,,1.00E-28,P78417,Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),GO:0019852; GO:0071243; GO:0005829; GO:0045174; GO:1901687; GO:0004364; GO:0050610; GO:0060315; GO:0060316; GO:0014810; GO:0010881; GO:0042178,L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; cytosol; glutathione dehydrogenase (ascorbate) activity; glutathione derivative biosynthetic process; glutathione transferase activity; methylarsonate reductase activity; negative regulation of ryanodine-sensitive calcium-release channel activity; positive regulation of ryanodine-sensitive calcium-release channel activity; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; xenobiotic catabolic process,PF14497;PF13417;,4.00E-13,CHOYP_GSTO1.1.2,,,,,,,GSTO1_HUMAN,Homo sapiens (Human),cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178] comp129465_c1_seq1,236,41.9492,1.06933831,7,64,,2.00E-06,Q8H8U5,Protein IN2-1 homolog B (Glutathione S-transferase GSTZ5),Protein IN2-1 homolog B (Glutathione S-transferase GSTZ5),,,PF13417;,1.00E-14,CHOYP_BRAFLDRAFT_100190.1.1,,,,,,,IN21B_ORYSJ,Oryza sativa subsp. japonica (Rice),glutathione metabolic process [GO:0006749]; protein glutathionylation [GO:0010731] comp129472_c0_seq1,480,39.1667,0.43672871,12,10,,2.00E-19,Q9M2F8,Carbon catabolite repressor protein 4 homolog 2 (CCR4 homolog 2) (EC 3.1.13.4),Carbon catabolite repressor protein 4 homolog 2 (CCR4 homolog 2) (EC 3.1.13.4),GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0005634; GO:0004535; GO:0006355; GO:0006351,"RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus; poly(A)-specific ribonuclease activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03372;,9.00E-13,CHOYP_BRAFLDRAFT_212438.1.1,,,,,,,CCR4B_ARATH,Arabidopsis thaliana (Mouse-ear cress),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129472_c1_seq1,496,41.5323,0.37491902,0,4,,4.00E-13,Q9C2R2,Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0005634; GO:0004535; GO:0006355; GO:0006351,"RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus; poly(A)-specific ribonuclease activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03372;,,,,,,,,,CCR4_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129472_c1_seq2,753,41.9655,0.33385721,18,26,,2.00E-44,Q08DF7,"2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)","2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)",GO:0016787; GO:0005739,hydrolase activity; mitochondrion,PF03372;,,,,,,,,,PDE12_BOVIN,Bos taurus (Bovine),mRNA processing [GO:0006397] comp129484_c0_seq1,1320,46.2879,0.41166823,24,18,,4.00E-120,Q8N201,Integrator complex subunit 1 (Int1),Integrator complex subunit 1 (Int1),GO:0034474; GO:0001833; GO:0016021; GO:0032039; GO:0043066; GO:0043154; GO:0031965; GO:0016180,U2 snRNA 3'-end processing; inner cell mass cell proliferation; integral to membrane; integrator complex; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nuclear membrane; snRNA processing,PF12432;,,,,,,,,,INT1_HUMAN,Homo sapiens (Human),snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp129484_c0_seq2,767,47.1969,0.4454628,0,0,,6.00E-16,Q54NC8,Integrator complex subunit 1 homolog,Integrator complex subunit 1 homolog,GO:0005634,nucleus,,1.00E-58,CHOYP_LOC100655005.1.1,,,,,,,INT1_DICDI,Dictyostelium discoideum (Slime mold), comp129485_c0_seq2,1074,45.0652,0.34885936,95,55,,7.00E-10,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129489_c1_seq1,408,43.6275,0.52591289,9,59,,2.00E-12,Q17QU7,Dehydrogenase/reductase SDR family member 13 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 13 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 7C member 5),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF00106;,,,,,,,,,DHR13_BOVIN,Bos taurus (Bovine), comp129489_c2_seq1,313,40.2556,0.39717076,3,43,,7.00E-28,Q8NBN7,Retinol dehydrogenase 13 (EC 1.1.1.-),Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3),GO:0005739; GO:0016491,mitochondrion; oxidoreductase activity,PF00106;,8.00E-18,CHOYP_LOC100699974.1.1,,,,,,,RDH13_HUMAN,Homo sapiens (Human),eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842] comp129495_c3_seq1,599,34.5576,0.61647846,15,72,,8.00E-21,Q9NYB9,Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1),Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1),GO:0003677; GO:0017124; GO:0008154; GO:0043010; GO:0016477; GO:0005913; GO:0008093; GO:0005856; GO:0005829; GO:0030425; GO:0016358; GO:0030175; GO:0019900; GO:0030027; GO:0007611; GO:0018108,DNA binding; SH3 domain binding; actin polymerization or depolymerization; camera-type eye development; cell migration; cell-cell adherens junction; cytoskeletal adaptor activity; cytoskeleton; cytosol; dendrite; dendrite development; filopodium; kinase binding; lamellipodium; learning or memory; peptidyl-tyrosine phosphorylation,PF07815;PF14604;,2.00E-29,CHOYP_LOC100372094.1.1,2.00E-39,ruditapes_c7207,,,,,ABI2_HUMAN,Homo sapiens (Human),actin polymerization or depolymerization [GO:0008154]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; movement of cell or subcellular component [GO:0006928]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; Rac protein signal transduction [GO:0016601]; viral process [GO:0016032] comp129496_c0_seq1,484,44.6281,0.58716958,8,71,,5.00E-24,Q01406,Src substrate protein p85 (Cortactin) (p80),Src substrate protein p85 (Cortactin) (p80),GO:0005856; GO:0043197; GO:0005783; GO:0030027; GO:0005886; GO:0001726,cytoskeleton; dendritic spine; endoplasmic reticulum; lamellipodium; plasma membrane; ruffle,PF02218;PF14604;,,,,,,,,,SRC8_CHICK,Gallus gallus (Chicken),actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; cell motility [GO:0048870]; focal adhesion assembly [GO:0048041]; intracellular protein transport [GO:0006886]; lamellipodium organization [GO:0097581]; neuron projection morphogenesis [GO:0048812]; positive regulation of actin filament polymerization [GO:0030838]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516] comp129505_c0_seq1,538,37.1747,0.81666949,6,130,,3.00E-33,P41247,Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2),Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2),GO:0016042; GO:0004806,lipid catabolic process; triglyceride lipase activity,PF01734;,,,,,,,,,PLPL4_HUMAN,Homo sapiens (Human),cellular lipid metabolic process [GO:0044255]; lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] comp129506_c1_seq1,638,46.395,0.85259009,20,32,,2.00E-12,Q6DFV8,von Willebrand factor D and EGF domain-containing protein,von Willebrand factor D and EGF domain-containing protein,GO:0005576,extracellular region,PF00094;,4.00E-13,CHOYP_BRAFLDRAFT_80496.1.10,,,,,,,VWDE_MOUSE,Mus musculus (Mouse), comp129510_c1_seq1,1616,36.6337,0.34492767,92,78,,1.00E-41,Q0P5H9,Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Strap),Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Strap),GO:0003677; GO:0006281; GO:0003682; GO:0005737; GO:0005634; GO:0045944,DNA binding; DNA repair; chromatin binding; cytoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter,PF16669;,2.00E-33,CHOYP_LOC100370957.1.1,,,,,,,TTC5_BOVIN,Bos taurus (Bovine),DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp129521_c0_seq1,1218,44.8276,0.45917726,66,41,,2.00E-36,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,2.00E-25,CHOYP_VP13D.1.3,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp129522_c0_seq1,693,32.6118,0.54504158,148,574,,,,,,,,,,,4.00E-11,ruditapes_c9634,,,,,,, comp129529_c0_seq1,714,40.4762,0.5507955,24,35,,8.00E-51,Q6IQ20,N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),GO:0070290; GO:0009395; GO:0042622; GO:0008270,NAPE-specific phospholipase D activity; phospholipid catabolic process; photoreceptor outer segment membrane; zinc ion binding,PF12706;,,,,,,,,,NAPEP_HUMAN,Homo sapiens (Human),phospholipid catabolic process [GO:0009395]; retinoid metabolic process [GO:0001523] comp129529_c0_seq2,319,41.6928,0.72398902,8,10,,9.00E-06,B4UGT5,UPF0173 metal-dependent hydrolase AnaeK_1127,UPF0173 metal-dependent hydrolase AnaeK_1127,GO:0016787,hydrolase activity,,2.00E-13,CHOYP_NAPEP.1.1,,,,,,,Y1127_ANASK,Anaeromyxobacter sp. (strain K), comp129531_c3_seq1,988,43.7247,0.42505684,0,0,,4.00E-51,Q9Y4I5,"Tesmin (Metallothionein-like 5, testis-specific) (Testis-specific metallothionein-like protein)","Tesmin (Metallothionein-like 5, testis-specific) (Testis-specific metallothionein-like protein)",GO:0030154; GO:0006875; GO:0005737; GO:0046872; GO:0007275; GO:0005634; GO:0010038; GO:0007283,cell differentiation; cellular metal ion homeostasis; cytoplasm; metal ion binding; multicellular organismal development; nucleus; response to metal ion; spermatogenesis,PF03638;,1.00E-134,CHOYP_LOC100377596.1.1,,,,,,,MTL5_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; cellular metal ion homeostasis [GO:0006875]; multicellular organism development [GO:0007275]; response to metal ion [GO:0010038]; spermatogenesis [GO:0007283] comp129531_c3_seq2,1079,44.5783,0.41118684,7,0,,2.00E-102,Q5RBN8,Protein lin-54 homolog,Protein lin-54 homolog,GO:0003677; GO:0007049; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell cycle; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03638;,,,,,,,,,LIN54_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129535_c0_seq2,469,38.806,0.24111948,78,16,,1.00E-08,Q5RCQ6,ADP-ribosylation factor-like protein 3,ADP-ribosylation factor-like protein 3,GO:0019003; GO:0005525; GO:0003924; GO:0005794; GO:0000139; GO:0005813; GO:0060271; GO:0000910; GO:0005881; GO:0042073; GO:0001822; GO:0008017; GO:0030496; GO:0005634; GO:0042461; GO:0032391; GO:0005886; GO:0015031; GO:0007264; GO:0005876,GDP binding; GTP binding; GTPase activity; Golgi apparatus; Golgi membrane; centrosome; cilium morphogenesis; cytokinesis; cytoplasmic microtubule; intraflagellar transport; kidney development; microtubule binding; midbody; nucleus; photoreceptor cell development; photoreceptor connecting cilium; plasma membrane; protein transport; small GTPase mediated signal transduction; spindle microtubule,PF00025;,,,,,,,,,ARL3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cilium morphogenesis [GO:0060271]; cytokinesis [GO:0000910]; kidney development [GO:0001822]; photoreceptor cell development [GO:0042461]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp129537_c0_seq1,876,37.3288,0.46346127,122,1364,,3.00E-13,P51397,Death-associated protein 1 (DAP-1),Death-associated protein 1 (DAP-1),GO:0006919; GO:0097190; GO:0006914; GO:0034198; GO:0032088; GO:0010507; GO:0045892,"activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; autophagy; cellular response to amino acid starvation; negative regulation of NF-kappaB transcription factor activity; negative regulation of autophagy; negative regulation of transcription, DNA-dependent",PF15228;,2.00E-11,CHOYP_HS12B.7.14,1.00E-56,ruditapes_c25615,,,,,DAP1_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular response to amino acid starvation [GO:0034198]; negative regulation of autophagy [GO:0010507]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]" comp129539_c0_seq2,644,45.1863,1.07561723,0,0,,3.00E-16,P16581,E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E),E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E),GO:0030029; GO:0007202; GO:0007596; GO:0019722; GO:0005901; GO:0005905; GO:0030863; GO:0005615; GO:0007157; GO:0016021; GO:0002523; GO:0050901; GO:0070492; GO:0048471; GO:0043274; GO:0002687; GO:0002092; GO:0050727; GO:0070555; GO:0032496; GO:0034612; GO:0033691; GO:0004888,actin filament-based process; activation of phospholipase C activity; blood coagulation; calcium-mediated signaling; caveola; coated pit; cortical cytoskeleton; extracellular space; heterophilic cell-cell adhesion; integral to membrane; leukocyte migration involved in inflammatory response; leukocyte tethering or rolling; oligosaccharide binding; perinuclear region of cytoplasm; phospholipase binding; positive regulation of leukocyte migration; positive regulation of receptor internalization; regulation of inflammatory response; response to interleukin-1; response to lipopolysaccharide; response to tumor necrosis factor; sialic acid binding; transmembrane signaling receptor activity,PF00008;PF00059;PF00084;,,,,,,,,,LYAM2_HUMAN,Homo sapiens (Human),actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612] comp129539_c0_seq3,517,46.2282,1.09252377,0,8,,1.00E-14,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp129539_c0_seq4,991,42.5832,0.94809517,0,0,,5.00E-19,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp129540_c0_seq1,1120,41.7857,0.47336957,137,183,,5.00E-88,Q8BR65,Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog),Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog),GO:0016580; GO:0006915; GO:0004407; GO:0042826; GO:0016575; GO:0000122; GO:0045892; GO:0043065; GO:0006351,"Sin3 complex; apoptotic process; histone deacetylase activity; histone deacetylase binding; histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of apoptotic process; transcription, DNA-dependent",PF08598;,5.00E-65,CHOYP_SDS3.1.1,,,,,,,SDS3_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; histone deacetylation [GO:0016575]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; transcription, DNA-templated [GO:0006351]" comp129542_c0_seq2,1107,39.9277,0.64880744,67,58,,3.00E-28,P27701,CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82),CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82),GO:0005887,integral to plasma membrane,PF00335;,1.00E-28,CHOYP_CD82.2.3,,,,,,,CD82_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166] comp129553_c0_seq1,764,41.2304,0.27856497,26,142,,5.00E-53,Q5EAC5,Zinc finger protein 410,Zinc finger protein 410,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,3.00E-13,ruditapes_c26765,,,,,ZN410_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129555_c0_seq1,763,33.4207,0.49290407,67,541,,6.00E-12,Q9Z2Q2,Lysine-rich nucleolar protein 1 (Testis-specific gene 118 protein),Lysine-rich nucleolar protein 1 (Testis-specific gene 118 protein),GO:0005730,nucleolus,PF15477;,,,,,,,,,CP088_MOUSE,Mus musculus (Mouse), comp129560_c0_seq1,1898,42.0443,0.28804614,43,210,,0,Q4JIJ3,Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),GO:0031419; GO:0005737; GO:0008898; GO:0008705; GO:0042558; GO:0008270,cobalamin binding; cytoplasm; homocysteine S-methyltransferase activity; methionine synthase activity; pteridine-containing compound metabolic process; zinc ion binding,PF02310;PF02607;PF02965;PF00809;PF02574;,0,CHOYP_METH.1.1,,,,,,,METH_BOVIN,Bos taurus (Bovine),pteridine-containing compound metabolic process [GO:0042558] comp129562_c0_seq1,666,43.5435,0.58326987,51,84,,4.00E-82,O60749,Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9),Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9),GO:0007154; GO:0031901; GO:0006897; GO:0010008; GO:0006886; GO:0035091; GO:0008565,cell communication; early endosome membrane; endocytosis; endosome membrane; intracellular protein transport; phosphatidylinositol binding; protein transporter activity,PF00787;PF03700;PF09325;,9.00E-53,CHOYP_SNX2.1.1,3.00E-88,ruditapes2_c2978,,,,,SNX2_HUMAN,Homo sapiens (Human),"early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; protein oligomerization [GO:0051259]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle organization [GO:0016050]" comp129565_c0_seq1,1483,44.3021,0.48379307,6,15,,6.00E-66,Q0IJ35,FERM domain-containing protein 8,FERM domain-containing protein 8,GO:0005856,cytoskeleton,PF00373;,,,,,,,,,FRMD8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp129565_c0_seq2,1970,40.6599,0.48167168,14,70,,3.00E-65,Q0IJ35,FERM domain-containing protein 8,FERM domain-containing protein 8,GO:0005856,cytoskeleton,PF00373;,4.00E-25,CHOYP_LOC658003.1.1,,,,,,,FRMD8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp129572_c0_seq2,1395,40.7168,0.46768934,4,24,,1.00E-109,Q91VA6,Polymerase delta-interacting protein 2,Polymerase delta-interacting protein 2,GO:0003677; GO:0005739; GO:0070584; GO:0005634; GO:0030674,"DNA binding; mitochondrion; mitochondrion morphogenesis; nucleus; protein binding, bridging",PF04379;PF08755;,,,,,,,,,PDIP2_MOUSE,Mus musculus (Mouse),mitochondrion morphogenesis [GO:0070584]; negative regulation of macroautophagy [GO:0016242]; positive regulation of mitotic cell cycle [GO:0045931] comp129574_c1_seq1,586,44.3686,0.3144652,19,136,,5.00E-48,Q9HC24,Protein lifeguard 4 (Golgi anti-apoptotic protein) (Protein S1R) (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein),Protein lifeguard 4 (Golgi anti-apoptotic protein) (Protein S1R) (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein),GO:0000139; GO:0005795; GO:0006915; GO:0016021; GO:0043066; GO:0050848,Golgi membrane; Golgi stack; apoptotic process; integral to membrane; negative regulation of apoptotic process; regulation of calcium-mediated signaling,,2.00E-41,CHOYP_BRAFLDRAFT_115358.2.2,,,,,,,LFG4_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; regulation of calcium-mediated signaling [GO:0050848] comp129577_c1_seq2,1720,45.7558,0.33718663,5,31,,2.00E-25,Q6DJL7,Protein aurora borealis,Protein aurora borealis,GO:0051301; GO:0007067; GO:0007088; GO:0060236; GO:0032880,cell division; mitosis; regulation of mitosis; regulation of mitotic spindle organization; regulation of protein localization,PF15280;,1.00E-17,CHOYP_BORA.1.1,,,,,,,BORA_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic nuclear division [GO:0007088]; regulation of mitotic spindle organization [GO:0060236]; regulation of protein localization [GO:0032880] comp129580_c0_seq1,1100,42.7273,0.65867243,5,248,,2.00E-73,P50429,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0007417; GO:0005764; GO:0046872; GO:0005739; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; central nervous system development; lysosome; metal ion binding; mitochondrion; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,2.00E-14,CHOYP_LOC100378957.1.1,7.00E-17,ruditapes2_c2269,,,,,ARSB_MOUSE,Mus musculus (Mouse),colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632] comp129582_c0_seq1,1055,38.9573,1.09485559,312,649,,1.00E-09,Q94521,Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),GO:0004059; GO:0004060; GO:0005737; GO:0048066; GO:0042420; GO:0030187; GO:0046334; GO:0045187; GO:0042429; GO:0030431,"aralkylamine N-acetyltransferase activity; arylamine N-acetyltransferase activity; cytoplasm; developmental pigmentation; dopamine catabolic process; melatonin biosynthetic process; octopamine catabolic process; regulation of circadian sleep/wake cycle, sleep; serotonin catabolic process; sleep",PF00583;,,,,,,,,,DNAT_DROME,Drosophila melanogaster (Fruit fly),"catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]" comp129585_c1_seq1,1495,44.3478,0.41064323,10,23,,,,,,,,,1.00E-17,CHOYP_LOC100378322.1.1,,,,,,,,, comp129585_c1_seq2,1516,44.1293,0.39566337,6,9,,2.00E-22,Q4V8C9,Leucine-rich repeat-containing protein 56,Leucine-rich repeat-containing protein 56,,,PF12799;,,,,,,,,,LRC56_RAT,Rattus norvegicus (Rat), comp129587_c2_seq2,1195,42.6778,0.55220428,44,137,,1.00E-124,Q9Z2A7,Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase),Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase),GO:0003846; GO:0004144; GO:0046339; GO:0005789; GO:0055089; GO:0016021; GO:0043231; GO:0019915; GO:0035336; GO:0050252; GO:0042572; GO:0019432; GO:0034379,2-acylglycerol O-acyltransferase activity; diacylglycerol O-acyltransferase activity; diacylglycerol metabolic process; endoplasmic reticulum membrane; fatty acid homeostasis; integral to membrane; intracellular membrane-bounded organelle; lipid storage; long-chain fatty-acyl-CoA metabolic process; retinol O-fatty-acyltransferase activity; retinol metabolic process; triglyceride biosynthetic process; very-low-density lipoprotein particle assembly,PF03062;,4.00E-67,CHOYP_DGAT1.1.2,,,,,,,DGAT1_MOUSE,Mus musculus (Mouse),diacylglycerol metabolic process [GO:0046339]; fatty acid homeostasis [GO:0055089]; lipid storage [GO:0019915]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; triglyceride biosynthetic process [GO:0019432]; very-low-density lipoprotein particle assembly [GO:0034379] comp129589_c0_seq1,1764,37.2449,0.34348079,779,166,,3.00E-47,Q6NXP6,NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148),NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148),GO:0006561; GO:0004735,proline biosynthetic process; pyrroline-5-carboxylate reductase activity,PF03807;,5.00E-36,CHOYP_LOC100375012.1.1,5.00E-52,ruditapes_c24537,,,,,NXRD1_HUMAN,Homo sapiens (Human),proline biosynthetic process [GO:0006561] comp129592_c0_seq1,1511,39.3779,0.34461554,551,1138,,4.00E-33,B5XBI1,Intraflagellar transport protein 43 homolog A,Intraflagellar transport protein 43 homolog A,GO:0060271; GO:0035721,cilium morphogenesis; intraflagellar retrograde transport,PF15305;,9.00E-51,CHOYP_LOC100368907.1.1,2.00E-102,ruditapes_c13475,,,,,IF43A_SALSA,Salmo salar (Atlantic salmon),cilium morphogenesis [GO:0060271]; intraciliary retrograde transport [GO:0035721] comp129600_c0_seq1,1186,40.2192,0.35625533,38,149,,1.00E-43,Q8NA58,Poly(A)-specific ribonuclease PARN-like domain-containing protein 1,Poly(A)-specific ribonuclease PARN-like domain-containing protein 1,GO:0016021; GO:0003676; GO:0005634,integral to membrane; nucleic acid binding; nucleus,PF04857;,,,4.00E-13,ruditapes_c24056,,,,,PNDC1_HUMAN,Homo sapiens (Human), comp129603_c0_seq1,631,31.5372,0.83242357,36,25,,4.00E-08,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp129610_c0_seq1,664,40.9639,0.21714335,8,10,,,,,,,,,5.00E-31,CHOYP_P3H2.1.1,,,,,,,,, comp129610_c0_seq2,2162,41.8131,0.49460163,91,150,,4.00E-51,Q8CG71,Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1),Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1),GO:0005794; GO:0031418; GO:0005604; GO:0032963; GO:0005783; GO:0005506; GO:0008285; GO:0019511; GO:0019797,Golgi apparatus; L-ascorbic acid binding; basement membrane; collagen metabolic process; endoplasmic reticulum; iron ion binding; negative regulation of cell proliferation; peptidyl-proline hydroxylation; procollagen-proline 3-dioxygenase activity,PF13640;,2.00E-30,CHOYP_P3H2.1.1,,,,,,,P3H2_MOUSE,Mus musculus (Mouse),collagen metabolic process [GO:0032963]; negative regulation of cell proliferation [GO:0008285]; peptidyl-proline hydroxylation [GO:0019511] comp129619_c0_seq2,1367,41.4045,0.53513051,0,0,,3.00E-25,Q6ZMV7,"Leucine-, glutamate- and lysine-rich protein 1","Leucine-, glutamate- and lysine-rich protein 1",,,,,,,,,,,,LEKR1_HUMAN,Homo sapiens (Human), comp129619_c0_seq5,1331,41.0969,0.52248041,0,0,,2.00E-25,Q6ZMV7,"Leucine-, glutamate- and lysine-rich protein 1","Leucine-, glutamate- and lysine-rich protein 1",,,,6.00E-21,CHOYP_LOC757085.1.1,,,,,,,LEKR1_HUMAN,Homo sapiens (Human), comp129621_c0_seq1,1275,44.7843,0.58546663,23,53,,1.00E-105,Q5BLE8,"Putative all-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat)","Putative all-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat)",GO:0051786; GO:0005789,"all-trans-retinol 13,14-reductase activity; endoplasmic reticulum membrane",PF01593;,1.00E-23,CHOYP_NEMVEDRAFT_V1G183264.2.2,,,,,,,RETST_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129621_c0_seq3,616,44.9675,0.52399289,0,0,,1.00E-07,P21334,"Phytoene desaturase (EC 1.3.99.30) (Albino-1 protein) (Phytoene desaturase (3,4-didehydrolycopene-forming))","Phytoene desaturase (EC 1.3.99.30) (Albino-1 protein) (Phytoene desaturase (3,4-didehydrolycopene-forming))",GO:0016117; GO:0016021; GO:0016491,carotenoid biosynthetic process; integral to membrane; oxidoreductase activity,PF01593;,,,,,,,,,CRTI_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),carotenoid biosynthetic process [GO:0016117] comp129622_c1_seq1,425,40,0.88455639,12,43,,2.00E-12,Q67S53,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ_SYMTH,Symbiobacterium thermophilum (strain T / IAM 14863),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp129637_c0_seq1,669,44.3946,0.64922626,0,0,,1.00E-34,Q75J93,Circularly permutated Ras protein 1 (DdiCPRas1),Circularly permutated Ras protein 1 (DdiCPRas1),GO:0030127; GO:0006888; GO:0005525; GO:0003924; GO:0006886; GO:0007264; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; GTP binding; GTPase activity; intracellular protein transport; small GTPase mediated signal transduction; zinc ion binding,PF00071;,2.00E-99,CHOYP_RALA.3.4,,,,,,,CPAS1_DICDI,Dictyostelium discoideum (Slime mold),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264] comp129637_c0_seq2,1467,38.0368,0.51781329,59,79,,2.00E-105,P48555,Ras-related protein Ral-a,Ras-related protein Ral-a,GO:0005525; GO:0003924; GO:0007464; GO:0007265; GO:0007298; GO:0050829; GO:0007391; GO:0045087; GO:0046329; GO:0045824; GO:0005886; GO:0008593; GO:0022604,GTP binding; GTPase activity; R3/R4 cell fate commitment; Ras protein signal transduction; border follicle cell migration; defense response to Gram-negative bacterium; dorsal closure; innate immune response; negative regulation of JNK cascade; negative regulation of innate immune response; plasma membrane; regulation of Notch signaling pathway; regulation of cell morphogenesis,PF00071;,2.00E-110,CHOYP_RALA.4.4,,,,,,,RALA_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; defense response to Gram-negative bacterium [GO:0050829]; dorsal closure [GO:0007391]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of JNK cascade [GO:0046329]; R3/R4 cell fate commitment [GO:0007464]; Ras protein signal transduction [GO:0007265]; regulation of cell morphogenesis [GO:0022604]; regulation of Notch signaling pathway [GO:0008593] comp129638_c0_seq1,641,41.0296,0.55923481,20,45,,2.00E-63,Q1L8G7,GATA zinc finger domain-containing protein 1,GATA zinc finger domain-containing protein 1,GO:0005634; GO:0043565; GO:0003700; GO:0008270,nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,,2.00E-35,CHOYP_GATAD1.1.1,3.00E-31,ruditapes_c15126,,,,,GATD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129645_c1_seq1,381,48.5564,0.94907486,1,43,,2.00E-47,P51824,ADP-ribosylation factor 1,ADP-ribosylation factor 1,GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,1.00E-34,CHOYP_LOC100637317.3.4,,,,,,,ARF1_SOLTU,Solanum tuberosum (Potato),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp129651_c0_seq1,977,41.044,0.45653575,0,0,,3.00E-104,P61460,DEP domain-containing protein 5,DEP domain-containing protein 5,GO:0005096; GO:0005829; GO:0035556; GO:0048471; GO:0043547,GTPase activator activity; cytosol; intracellular signal transduction; perinuclear region of cytoplasm; positive regulation of GTPase activity,PF00610;PF12257;,8.00E-138,CHOYP_LOC100121949.1.2,,,,,,,DEPD5_MOUSE,Mus musculus (Mouse),cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007] comp129651_c0_seq3,1024,40.918,0.41088985,4,4,,1.00E-140,O75140,DEP domain-containing protein 5,DEP domain-containing protein 5,GO:0005096; GO:0005829; GO:0035556; GO:0005765; GO:0048471; GO:0043547,GTPase activator activity; cytosol; intracellular signal transduction; lysosomal membrane; perinuclear region of cytoplasm; positive regulation of GTPase activity,PF00610;PF12257;,7.00E-139,CHOYP_LOC100121949.2.2,,,,,,,DEPD5_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007] comp129658_c0_seq1,1338,36.4723,0.86164784,23,322,,3.00E-15,Q0V8E7,Stimulated by retinoic acid gene 6 protein homolog,Stimulated by retinoic acid gene 6 protein homolog,GO:0016021; GO:0005886; GO:0004872; GO:0051180; GO:0051183,integral to membrane; plasma membrane; receptor activity; vitamin transport; vitamin transporter activity,,8.00E-32,CHOYP_BRAFLDRAFT_64338.1.2,,,,,,,STRA6_BOVIN,Bos taurus (Bovine), comp129660_c0_seq2,676,47.6331,0.23597124,0,0,,3.00E-12,O08523,Alpha-tectorin,Alpha-tectorin,GO:0031225; GO:0007160; GO:0005201; GO:0005886; GO:0005578; GO:0007605,anchored to membrane; cell-matrix adhesion; extracellular matrix structural constituent; plasma membrane; proteinaceous extracellular matrix; sensory perception of sound,PF08742;PF06119;PF01826;PF12714;PF00094;PF00100;,,,,,,,,,TECTA_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605] comp129660_c0_seq3,1445,46.7128,0.28316108,36,33,,4.00E-102,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp129663_c0_seq1,970,42.9897,0.49241673,23,139,,2.00E-100,Q8CFY5,"Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.-) (Heme O synthase)","Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.-) (Heme O synthase)",GO:0009060; GO:0017004; GO:0004129; GO:0048034; GO:0006784; GO:0016021; GO:0000266; GO:0031966; GO:0005739; GO:0008495; GO:0008535,aerobic respiration; cytochrome complex assembly; cytochrome-c oxidase activity; heme O biosynthetic process; heme a biosynthetic process; integral to membrane; mitochondrial fission; mitochondrial membrane; mitochondrion; protoheme IX farnesyltransferase activity; respiratory chain complex IV assembly,PF01040;,1.00E-58,CHOYP_LOC100695060.1.1,,,,,,,COX10_MOUSE,Mus musculus (Mouse),aerobic respiration [GO:0009060]; cellular respiration [GO:0045333]; cytochrome complex assembly [GO:0017004]; heme a biosynthetic process [GO:0006784]; heme O biosynthetic process [GO:0048034]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]; protein farnesylation [GO:0018343]; respiratory chain complex IV assembly [GO:0008535] comp129675_c0_seq1,1139,42.5812,0.62036644,39,321,,3.00E-38,Q8BJ90,Zinc finger protein 771,Zinc finger protein 771,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN771_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129676_c0_seq2,747,40.0268,1.10472808,0,16,,,,,,,,,,,2.00E-53,ruditapes_c27124,,,,,,, comp129687_c0_seq2,694,42.9395,1.08593975,19,249,,,,,,,,,,,1.00E-16,ruditapes2_c2130,,,,,,, comp129688_c0_seq1,906,40.1766,0.90404242,7,424,,,,,,,,,,,1.00E-11,ruditapes_c1969,,,,,,, comp129691_c0_seq3,1364,44.5748,0.98378431,0,0,,3.00E-43,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp129691_c0_seq6,1613,39.9256,0.9866391,0,0,,1.00E-38,Q9Z0E8,Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2),Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2),GO:0005524; GO:0007512; GO:0016324; GO:0031526; GO:0009437; GO:0015226; GO:0016021; GO:0007626; GO:0007005; GO:0048608; GO:0006814; GO:0015293,ATP binding; adult heart development; apical plasma membrane; brush border membrane; carnitine metabolic process; carnitine transmembrane transporter activity; integral to membrane; locomotory behavior; mitochondrion organization; reproductive structure development; sodium ion transport; symporter activity,PF00083;,,,,,,,,,S22A5_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; locomotory behavior [GO:0007626]; mitochondrion organization [GO:0007005]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; quorum sensing involved in interaction with host [GO:0052106]; reproductive structure development [GO:0048608]; sodium-dependent organic cation transport [GO:0070715]; sodium ion transport [GO:0006814] comp129691_c0_seq7,925,45.2973,0.90052898,0,0,,1.00E-24,Q95R48,Organic cation transporter-like protein,Organic cation transporter-like protein,GO:0007390; GO:0016021; GO:0015101; GO:0030307; GO:0040018,germ-band shortening; integral to membrane; organic cation transmembrane transporter activity; positive regulation of cell growth; positive regulation of multicellular organism growth,PF00083;,,,,,,,,,OCTL_DROME,Drosophila melanogaster (Fruit fly),germ-band shortening [GO:0007390]; organic cation transport [GO:0015695]; positive regulation of cell growth [GO:0030307]; positive regulation of multicellular organism growth [GO:0040018] comp129699_c0_seq3,823,40.7047,0.85391778,2,0,,2.00E-08,Q3U2S8,Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein) (mVSOP),Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein) (mVSOP),GO:0016021; GO:0009268; GO:0010043; GO:0030171,integral to membrane; response to pH; response to zinc ion; voltage-gated proton channel activity,PF00520;PF16799;,3.00E-60,CHOYP_HVCN1.1.4,,,,,,,HVCN1_MOUSE,Mus musculus (Mouse),cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transport [GO:0015992]; response to pH [GO:0009268]; response to zinc ion [GO:0010043] comp129707_c0_seq2,2265,42.2075,0.46194627,53,54,,2.00E-148,Q8N8E3,Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46),Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46),GO:0005813; GO:0005737; GO:0060077; GO:0005886; GO:0097120,centrosome; cytoplasm; inhibitory synapse; plasma membrane; receptor localization to synapse,PF14846;,6.00E-137,CHOYP_CE112.2.2,,,,,,,CE112_HUMAN,Homo sapiens (Human),receptor localization to synapse [GO:0097120] comp129712_c0_seq3,375,42.6667,0.23953029,0,0,,,,,,,,,4.00E-22,CHOYP_LOC100373982.2.2,,,,,,,,, comp129712_c0_seq5,606,37.6238,0.39098335,0,0,,6.00E-17,Q9BUN5,Coiled-coil domain-containing protein 28B,Coiled-coil domain-containing protein 28B,GO:0005813; GO:0042384; GO:0005737,centrosome; cilium assembly; cytoplasm,PF13270;,1.00E-25,CHOYP_LOC100373982.1.2,,,,,,,CC28B_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384] comp129712_c0_seq8,336,43.75,0.38208955,0,0,,,,,,,,,4.00E-22,CHOYP_LOC100373982.2.2,,,,,,,,, comp129712_c0_seq9,422,39.8104,0.36597177,0,0,,,,,,,,,8.00E-26,CHOYP_LOC100373982.1.2,,,,,,,,, comp129721_c0_seq2,947,38.226,0.55006933,6,32,,,,,,,,,,,9.00E-78,ruditapes_c23951,,,,,,, comp129724_c0_seq2,743,41.5882,0.46863275,25,9,,4.00E-115,Q5ZHN3,WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2),WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2),GO:0000045; GO:0000421; GO:0005829; GO:0005634; GO:0080025; GO:0032266; GO:0034045; GO:0043234,"autophagic vacuole assembly; autophagic vacuole membrane; cytosol; nucleus; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; pre-autophagosomal structure membrane; protein complex",,,,,,,,,,WIPI2_CHICK,Gallus gallus (Chicken),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497] comp129724_c0_seq3,401,37.4065,0.50169683,0,9,,7.00E-20,Q5QJC0,Autophagy-related protein 21,Autophagy-related protein 21,GO:0006914; GO:0015031; GO:0005774,autophagy; protein transport; vacuolar membrane,PF00400;,,,,,,,,,ATG21_PICAN,Pichia angusta (Yeast) (Hansenula polymorpha),autophagy [GO:0006914]; protein transport [GO:0015031] comp129724_c1_seq1,464,42.0259,0.53808371,16,18,,7.00E-32,Q4P4N1,Autophagy-related protein 18,Autophagy-related protein 18,GO:0006914; GO:0010008; GO:0034045; GO:0015031; GO:0005774,autophagy; endosome membrane; pre-autophagosomal structure membrane; protein transport; vacuolar membrane,,9.00E-108,CHOYP_WIPI2.2.2,,,,,,,ATG18_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497]; protein transport [GO:0015031] comp129730_c0_seq1,2468,43.0713,0.48960001,0,0,,3.00E-12,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp129730_c0_seq6,501,41.3174,0.37879796,0,0,,3.00E-11,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp129738_c0_seq1,619,50.8885,0.6814314,47,18,,5.00E-70,Q9GKN7,Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (CD antigen CD241),Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (CD antigen CD241),GO:0051739; GO:0008519; GO:0006873; GO:0016021; GO:0005886,ammonia transmembrane transporter activity; ammonium transmembrane transporter activity; cellular ion homeostasis; integral to membrane; plasma membrane,PF00909;,8.00E-47,CHOYP_LOC100370684.2.2,,,,,,,RHAG_BOVIN,Bos taurus (Bovine),ammonium transmembrane transport [GO:0072488]; ammonium transport [GO:0015696]; cellular ion homeostasis [GO:0006873]; nitrogen utilization [GO:0019740]; organic cation transport [GO:0015695] comp129740_c0_seq1,458,39.3013,0.69231099,3,12,,4.00E-08,Q0P3X7,UPF0545 protein C22orf39 homolog,UPF0545 protein C22orf39 homolog,,,PF11326;,,,,,,,,,CV039_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129740_c0_seq2,727,35.6259,0.52951973,119,303,,1.00E-08,A2BD89,UPF0545 protein C22orf39 homolog,UPF0545 protein C22orf39 homolog,,,PF11326;,,,,,,,,,CV039_XENLA,Xenopus laevis (African clawed frog), comp129748_c0_seq1,1491,45.1375,0.81998406,3,521,female>male,,,,,,,,,,5.00E-33,ruditapes_c2097,,,,,,, comp129748_c1_seq1,622,48.2315,1.02741396,0,75,,2.00E-15,Q641F3,Collagen alpha-1(XXI) chain,Collagen alpha-1(XXI) chain,GO:0005581; GO:0005737,collagen; cytoplasm,PF01391;PF00092;,,,,,,,,,COLA1_XENLA,Xenopus laevis (African clawed frog), comp129765_c0_seq1,949,44.5732,1.19658253,96,0,,8.00E-23,P46272,TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit),TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit),GO:0003677; GO:0006352; GO:0005634,"DNA binding; DNA-dependent transcription, initiation; nucleus",PF00352;,,,3.00E-33,ruditapes_c16257,,,,,TBP_ACECL,Acetabularia peniculus (Green alga) (Polyphysa peniculus),"DNA-templated transcription, initiation [GO:0006352]" comp129773_c1_seq1,558,41.9355,0.32690163,3,72,,8.00E-58,Q0V9A9,Beta-lactamase-like protein 2 (EC 3.-.-.-),Endoribonuclease LACTB2 (Beta-lactamase-like protein 2) (EC 3.1.27.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF00753;,3.00E-19,CHOYP_LACB2.1.1,,,,,,,LACB2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" comp129778_c0_seq8,825,32.7273,0.2744798,1,0,,,,,,,,,2.00E-11,CHOYP_contig_032397,,,,,,,,, comp129782_c0_seq1,656,35.2134,0.40030558,192,265,,3.00E-54,A4F4L4,"Dynein light chain 4, axonemal","Dynein light chain 4, axonemal",GO:0035085; GO:0030286; GO:0005874; GO:0007017; GO:0003774,cilium axoneme; dynein complex; microtubule; microtubule-based process; motor activity,PF01221;,2.00E-85,CHOYP_LOC100375307.2.2,,,,,,,DNAL4_PIG,Sus scrofa (Pig),microtubule-based process [GO:0007017] comp129784_c0_seq1,1361,28.2145,0.26175782,148,484,,,,,,,,,,,6.00E-12,ruditapes2_c1567,,,,,,, comp129785_c0_seq2,809,45.6119,0.54819999,8,51,,4.00E-40,Q8BHA0,INO80 complex subunit C,INO80 complex subunit C,GO:0006310; GO:0006281; GO:0071339; GO:0006355; GO:0006351,"DNA recombination; DNA repair; MLL1 complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08265;,1.00E-26,CHOYP_BRAFLDRAFT_105224.1.1,2.00E-53,ruditapes_c29297,,,,,IN80C_MOUSE,Mus musculus (Mouse),"chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129789_c0_seq1,1703,45.6254,0.26395128,169,63,,0,Q9NU22,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0016887; GO:0005730; GO:0005634; GO:0006461; GO:0051082,ATP binding; ATPase activity; nucleolus; nucleus; protein complex assembly; unfolded protein binding,PF07728;,3.00E-51,CHOYP_MDN1.2.8,,,,,,,MDN1_HUMAN,Homo sapiens (Human),protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027] comp129791_c0_seq1,1353,36.8071,0.4838859,127,1241,,2.00E-167,B0WEV5,ATPase ASNA1 homolog (EC 3.6.-.-) (Arsenical pump-driving ATPase homolog) (Arsenite-stimulated ATPase),ATPase ASNA1 homolog (EC 3.6.-.-) (Arsenical pump-driving ATPase homolog) (Arsenite-stimulated ATPase),GO:0005524; GO:0006200; GO:0016887; GO:0005783; GO:0046872; GO:0045048; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; endoplasmic reticulum; metal ion binding; protein insertion into ER membrane; transport,PF02374;,1.00E-169,CHOYP_ASNA.1.1,,,,,,,ASNA_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),protein insertion into ER membrane [GO:0045048]; transport [GO:0006810] comp129793_c0_seq1,341,42.522,0.19528147,12,27,,6.00E-14,Q69ZL1,"FYVE, RhoGEF and PH domain-containing protein 6","FYVE, RhoGEF and PH domain-containing protein 6",GO:0005089; GO:0005737; GO:0005856; GO:0046872; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cytoplasm; cytoskeleton; metal ion binding; phospholipid binding; regulation of Rho protein signal transduction,PF01363;PF00169;PF00621;,,,,,,,,,FGD6_MOUSE,Mus musculus (Mouse),regulation of Rho protein signal transduction [GO:0035023] comp129793_c1_seq2,969,44.8916,0.55130562,0,0,,2.00E-10,Q91VS8,"FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)","FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)",GO:0030676; GO:0016601; GO:0031532; GO:0007155; GO:0005856; GO:0005829; GO:0019898; GO:0016322; GO:0030316; GO:0005543; GO:0071800; GO:0035023; GO:0033623; GO:0071526,Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; actin cytoskeleton reorganization; cell adhesion; cytoskeleton; cytosol; extrinsic to membrane; neuron remodeling; osteoclast differentiation; phospholipid binding; podosome assembly; regulation of Rho protein signal transduction; regulation of integrin activation; semaphorin-plexin signaling pathway,PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;,,,,,,,,,FARP2_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526] comp129798_c1_seq1,1068,29.588,0.86900048,20,360,,,,,,,,,,,1.00E-13,ruditapes_c27413,,,,,,, comp129810_c0_seq1,534,36.3296,0.57250067,3,7,,,,,,,,,5.00E-11,CHOYP_XYLK.1.1,,,,,,,,, comp129810_c0_seq2,1659,37.9144,0.33998988,64,225,,7.00E-132,O75063,Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Protein FAM20B) (Xylose kinase),Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase),GO:0005524; GO:0005794; GO:0000139; GO:0016021; GO:0016301; GO:0016773,"ATP binding; Golgi apparatus; Golgi membrane; integral to membrane; kinase activity; phosphotransferase activity, alcohol group as acceptor",PF06702;,,,,,,,,,XYLK_HUMAN,Homo sapiens (Human),positive regulation of protein targeting to mitochondrion [GO:1903955] comp129812_c2_seq1,261,37.1648,1.13421578,9,28,,,,,,,,,,,3.00E-13,ruditapes_c3364,,,,,,, comp129815_c1_seq3,1135,39.8238,0.42662905,0,9,,,,,,,,,2.00E-12,CHOYP_LOC578100.2.3,,,,,,,,, comp129815_c1_seq4,1518,39.3939,0.39376743,113,142,,2.00E-81,Q6PCB5,Round spermatid basic protein 1-like protein,Round spermatid basic protein 1-like protein,GO:0005634,nucleus,,6.00E-40,CHOYP_LOC578100.1.3,,,,,,,RSBNL_HUMAN,Homo sapiens (Human), comp129816_c0_seq1,288,41.6667,0.40420068,7,9,,2.00E-18,Q9JIB0,Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1),Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1),GO:0008536; GO:0005087; GO:0005737; GO:0014704; GO:0006913; GO:0005654; GO:0015031; GO:0003254; GO:2000649; GO:0017080,Ran GTPase binding; Ran guanyl-nucleotide exchange factor activity; cytoplasm; intercalated disc; nucleocytoplasmic transport; nucleoplasm; protein transport; regulation of membrane depolarization; regulation of sodium ion transmembrane transporter activity; sodium channel regulator activity,PF04603;,,,,,,,,,MOG1_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; nucleocytoplasmic transport [GO:0006913]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to cell surface [GO:2000010]; protein exit from endoplasmic reticulum [GO:0032527]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of sodium ion transmembrane transporter activity [GO:2000649] comp129816_c1_seq1,994,37.9276,0.47928758,21,81,,6.00E-08,Q54ML6,Probable ran guanine nucleotide release factor (RanGNRF),Probable ran guanine nucleotide release factor (RanGNRF),GO:0008536; GO:0005829; GO:0005085; GO:0005634; GO:0015031; GO:0007264,Ran GTPase binding; cytosol; guanyl-nucleotide exchange factor activity; nucleus; protein transport; small GTPase mediated signal transduction,PF04603;,,,,,,,,,MOG1_DICDI,Dictyostelium discoideum (Slime mold),protein transport [GO:0015031] comp129816_c1_seq2,515,39.0291,0.40993203,0,0,,6.00E-12,Q9HD47,Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1),Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1),GO:0006888; GO:0008536; GO:0005901; GO:0005085; GO:0014704; GO:0005654; GO:0090004; GO:2000010; GO:0032527; GO:0008565; GO:0002027; GO:1900825; GO:0042391; GO:2000649; GO:0005791; GO:0017080,ER to Golgi vesicle-mediated transport; Ran GTPase binding; caveola; guanyl-nucleotide exchange factor activity; intercalated disc; nucleoplasm; positive regulation of establishment of protein localization to plasma membrane; positive regulation of protein localization to cell surface; protein exit from endoplasmic reticulum; protein transporter activity; regulation of heart rate; regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential; regulation of membrane potential; regulation of sodium ion transmembrane transporter activity; rough endoplasmic reticulum; sodium channel regulator activity,PF04603;,,,,,,,,,MOG1_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein localization to cell surface [GO:2000010]; protein exit from endoplasmic reticulum [GO:0032527]; regulation of heart rate [GO:0002027]; regulation of membrane depolarization [GO:0003254]; regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900825]; regulation of membrane potential [GO:0042391]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of sodium ion transmembrane transporter activity [GO:2000649] comp129820_c0_seq1,1151,41.0947,1.24044457,25,131,,1.00E-14,Q9W740,Noggin-2,Noggin-2,GO:0051216; GO:0030154; GO:0005576; GO:0030514; GO:0045596,cartilage development; cell differentiation; extracellular region; negative regulation of BMP signaling pathway; negative regulation of cell differentiation,,,,,,,,,,NOGG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cartilage development [GO:0051216]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; nervous system development [GO:0007399]; osteoblast differentiation [GO:0001649]; skeletal system development [GO:0001501] comp129826_c0_seq1,229,41.4847,0.61171379,7,2,,5.00E-12,P56671,Myc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor),Myc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor),GO:0003677; GO:0003682; GO:0005737; GO:0046872; GO:0005634; GO:0045944; GO:0000981,DNA binding; chromatin binding; cytoplasm; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF00096;,,,,,,,,,MAZ_MOUSE,Mus musculus (Mouse),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; termination of RNA polymerase II transcription [GO:0006369]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp129826_c1_seq1,1228,38.9251,0.40937965,40,194,,1.00E-25,Q6ZMW2,Zinc finger protein 782,Zinc finger protein 782,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN782_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129828_c0_seq1,938,35.5011,0.90536334,11,72,,9.00E-10,Q32KU6,Tetraspanin-6 (Tspan-6),Tetraspanin-6 (Tspan-6),GO:0016021; GO:0043123; GO:0004871,integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity,PF00335;,,,,,,,,,TSN6_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway [GO:0039532]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp129828_c0_seq2,581,38.7263,0.83982933,0,0,,3.00E-09,Q5RE11,Tetraspanin-3 (Tspan-3),Tetraspanin-3 (Tspan-3),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp129833_c0_seq1,2585,47.0019,0.54219749,11,0,,0,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,3.00E-15,CHOYP_HMCN1.28.44,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp129833_c0_seq2,2549,46.2927,0.52315258,8,0,,6.00E-38,Q91048,Inactive tyrosine-protein kinase 7 (Kinase-like protein) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7),Inactive tyrosine-protein kinase 7 (Kinase-like protein) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7),GO:0005524; GO:0016055; GO:0007155; GO:0016021; GO:0018108; GO:0004713,ATP binding; Wnt receptor signaling pathway; cell adhesion; integral to membrane; peptidyl-tyrosine phosphorylation; protein tyrosine kinase activity,PF07679;PF07714;,,,,,,,,,PTK7_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; Wnt signaling pathway [GO:0016055] comp129833_c0_seq4,1992,47.1888,0.53545031,2,0,,7.00E-151,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp129841_c0_seq2,1958,41.3687,0.97935096,7,299,,4.00E-170,Q8HZK2,Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox),Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox),GO:0016174; GO:0016324; GO:0005509; GO:0042335; GO:0019221; GO:0020037; GO:0042446; GO:0042744; GO:0016021; GO:0055114; GO:0004601; GO:0051591; GO:0006590,NAD(P)H oxidase activity; apical plasma membrane; calcium ion binding; cuticle development; cytokine-mediated signaling pathway; heme binding; hormone biosynthetic process; hydrogen peroxide catabolic process; integral to membrane; oxidation-reduction process; peroxidase activity; response to cAMP; thyroid hormone generation,PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;,4.00E-170,CHOYP_DUOX1.2.4,,,,,,,DUOX2_PIG,Sus scrofa (Pig),cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590] comp129846_c1_seq2,996,40.9639,0.70083697,70,625,,3.00E-43,Q7ZVP8,Trimeric intracellular cation channel type B (TRIC-B) (TRICB) (Transmembrane protein 38B),Trimeric intracellular cation channel type B (TRIC-B) (TRICB) (Transmembrane protein 38B),GO:0005789; GO:0016021; GO:0005267,endoplasmic reticulum membrane; integral to membrane; potassium channel activity,PF05197;,7.00E-88,CHOYP_ISCW_ISCW018083.1.1,7.00E-54,ruditapes_c12555,,,,,TM38B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129847_c0_seq1,1570,43.4395,0.68592464,0,0,,,,,,,,,2.00E-60,CHOYP_PHUM_PHUM195100.1.1,,,,,,,,, comp129847_c0_seq2,2673,45.8287,0.6361562,81,129,,0,Q9P203,BTB/POZ domain-containing protein 7,BTB/POZ domain-containing protein 7,,,PF07707;PF00651;,2.00E-107,CHOYP_PHUM_PHUM195100.1.1,,,,,,,BTBD7_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; regulation of branching involved in salivary gland morphogenesis [GO:0060693] comp129848_c0_seq1,607,35.2554,0.43224146,14,168,,2.00E-43,Q5R7A2,"Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase)","Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase)",GO:0004578; GO:0005789; GO:0016021; GO:0006486,chitobiosyldiphosphodolichol beta-mannosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; protein glycosylation,PF00534;,,,,,,,,,ALG1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein glycosylation [GO:0006486] comp129851_c0_seq1,2282,40.0964,0.31695285,6,6,,6.00E-75,Q9WTK2,Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48),Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48),GO:0016573; GO:0004402; GO:0035064; GO:0005634; GO:0006355; GO:0003714; GO:0006351,"histone acetylation; histone acetyltransferase activity; methylated histone residue binding; nucleus; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF00385;PF00378;,3.00E-91,CHOYP_LOC100370742.1.1,,,,,,,CDYL_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp129851_c0_seq2,2236,41.2791,0.30503213,0,6,,2.00E-68,Q8N8U2,Chromodomain Y-like protein 2 (CDY-like 2),Chromodomain Y-like protein 2 (CDY-like 2),GO:0003824; GO:0005634,catalytic activity; nucleus,PF00385;PF00378;,,,,,,,,,CDYL2_HUMAN,Homo sapiens (Human),metabolic process [GO:0008152] comp129869_c0_seq1,854,43.911,0.71857167,34,31,,2.00E-40,Q91286,Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (PFR2),Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (PFR2),GO:0005524; GO:0005794; GO:0001525; GO:0006915; GO:0007409; GO:0030282; GO:0060349; GO:0060667; GO:0048755; GO:0060449; GO:0045165; GO:0007267; GO:0016023; GO:0048701; GO:0048557; GO:0009880; GO:0048730; GO:0060664; GO:0017134; GO:0005007; GO:0016021; GO:0032808; GO:0060601; GO:0060174; GO:0048286; GO:0060463; GO:0060484; GO:0003149; GO:0060915; GO:0060916; GO:0030901; GO:0016331; GO:0035264; GO:0000122; GO:0005634; GO:0042476; GO:0035265; GO:0030916; GO:0003148; GO:0018108; GO:0005886; GO:0070374; GO:0090263; GO:0060045; GO:0051781; GO:0060501; GO:0002053; GO:0045944; GO:0009791; GO:0060527; GO:0060523; GO:0060687; GO:0010453; GO:0040036; GO:0040014; GO:0051150; GO:0008589; GO:0060529; GO:0001657; GO:0055010,ATP binding; Golgi apparatus; angiogenesis; apoptotic process; axonogenesis; bone mineralization; bone morphogenesis; branch elongation involved in salivary gland morphogenesis; branching morphogenesis of a nerve; bud elongation involved in lung branching; cell fate commitment; cell-cell signaling; cytoplasmic membrane-bounded vesicle; embryonic cranial skeleton morphogenesis; embryonic digestive tract morphogenesis; embryonic pattern specification; epidermis morphogenesis; epithelial cell proliferation involved in salivary gland morphogenesis; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; integral to membrane; lacrimal gland development; lateral sprouting from an epithelium; limb bud formation; lung alveolus development; lung lobe morphogenesis; lung-associated mesenchyme development; membranous septum morphogenesis; mesenchymal cell differentiation involved in lung development; mesenchymal cell proliferation involved in lung development; midbrain development; morphogenesis of embryonic epithelium; multicellular organism growth; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis; organ growth; otic vesicle formation; outflow tract septum morphogenesis; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of cell division; positive regulation of epithelial cell proliferation involved in lung morphogenesis; positive regulation of mesenchymal cell proliferation; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; prostate epithelial cord elongation; regulation of branching involved in prostate gland morphogenesis; regulation of cell fate commitment; regulation of fibroblast growth factor receptor signaling pathway; regulation of multicellular organism growth; regulation of smooth muscle cell differentiation; regulation of smoothened signaling pathway; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ureteric bud development; ventricular cardiac muscle tissue morphogenesis,PF07679;PF07714;,,,,,,,,,FGFR2_PLEWA,Pleurodeles waltl (Iberian ribbed newt),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; digestive tract development [GO:0048565]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; gland morphogenesis [GO:0022612]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; multicellular organism growth [GO:0035264]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; organ growth [GO:0035265]; organ morphogenesis [GO:0009887]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of cell fate commitment [GO:0010453]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of multicellular organism growth [GO:0040014]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] comp129881_c1_seq1,537,32.7747,0.85228018,17,50,,9.00E-14,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp129892_c0_seq1,2031,44.8548,0.63459733,161,20,,4.00E-23,Q8BVU5,"ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)","ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)",GO:0046032; GO:0047631; GO:0046709; GO:0043262; GO:0005739,ADP catabolic process; ADP-ribose diphosphatase activity; IDP catabolic process; adenosine-diphosphatase activity; mitochondrion,PF00293;,2.00E-34,CHOYP_BRAFLDRAFT_118277.1.1,,,,,,,NUDT9_MOUSE,Mus musculus (Mouse),ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709] comp129892_c2_seq1,526,40.1141,0.37947932,17,0,,,,,,,,,1.00E-24,CHOYP_ISCW_ISCW010958.1.1,,,,,,,,, comp129892_c2_seq2,276,41.6667,0.33515262,0,0,,,,,,,,,6.00E-25,CHOYP_ISCW_ISCW010958.1.1,,,,,,,,, comp129896_c0_seq1,932,43.4549,1.11625727,20,131,,2.00E-44,Q4R877,Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3),Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3),GO:0016021; GO:0015888; GO:0015403,integral to membrane; thiamine transport; thiamine uptake transmembrane transporter activity,PF01770;,,,,,,,,,S19A3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp129897_c0_seq1,1161,40.0517,0.97818839,20,235,,1.00E-56,Q9CZR2,N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II),N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II),GO:0050129; GO:0004180; GO:0016805; GO:0016021; GO:0046872; GO:0008237; GO:0042135; GO:0006508,N-formylglutamate deformylase activity; carboxypeptidase activity; dipeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; neurotransmitter catabolic process; proteolysis,PF02225;PF04389;PF04253;,,,4.00E-32,ruditapes2_c2914,,,,,NALD2_MOUSE,Mus musculus (Mouse),neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] comp129898_c0_seq1,1309,40.4125,0.45185424,76,255,,3.00E-30,Q3KNJ2,Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor),Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor),GO:0030183; GO:0003677; GO:0006310; GO:0030217; GO:0006303; GO:0070419; GO:0005634; GO:0010212,B cell differentiation; DNA binding; DNA recombination; T cell differentiation; double-strand break repair via nonhomologous end joining; nonhomologous end joining complex; nucleus; response to ionizing radiation,PF09302;,5.00E-22,CHOYP_LOC754820.1.1,3.00E-41,ruditapes_c23666,,,,,NHEJ1_MOUSE,Mus musculus (Mouse),B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ionizing radiation [GO:0010212]; T cell differentiation [GO:0030217] comp129899_c0_seq1,1298,43.0663,0.72543486,14,513,,2.00E-33,Q9P6J4,Uncharacterized protein C1683.06c,Uncharacterized protein C1683.06c,GO:0034356; GO:0005829; GO:0070635; GO:0019358; GO:0070636; GO:0005634; GO:0046135; GO:0008655; GO:0045437,NAD biosynthesis via nicotinamide riboside salvage pathway; cytosol; nicotinamide riboside hydrolase activity; nicotinate nucleotide salvage; nicotinic acid riboside hydrolase activity; nucleus; pyrimidine nucleoside catabolic process; pyrimidine-containing compound salvage; uridine nucleosidase activity,PF01156;,,,,,,,,,YHD6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinate nucleotide salvage [GO:0019358]; purine nucleoside catabolic process [GO:0006152]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside catabolic process [GO:0046135] comp129900_c0_seq1,673,34.9183,0.35140849,12,176,,1.00E-12,O35207,Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor),Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor),GO:0007049,cell cycle,PF09806;,,,,,,,,,CDKA1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; positive regulation of protein phosphorylation [GO:0001934] comp129901_c3_seq1,593,41.484,0.86383112,18,17,,2.00E-24,Q7T3E6,Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B),Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B),GO:0031519; GO:0016568; GO:0006355; GO:0006351; GO:0008270,"PcG protein complex; chromatin modification; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF16207;,,,,,,,,,BMI1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cerebellum development [GO:0021549]; chromatin modification [GO:0016568]; negative regulation of gene expression, epigenetic [GO:0045814]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp129905_c0_seq1,261,41.7625,0.5981823,3,5,,8.00E-11,Q16KN5,Protein real-time,Protein real-time,GO:0016021; GO:0005739; GO:0006810,integral to membrane; mitochondrion; transport,PF00650;PF03765;PF04707;,,,,,,,,,RETM_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),transport [GO:0006810] comp129905_c0_seq2,1086,40.2394,0.51152985,20,8,,2.00E-69,Q8R0F9,SEC14-like protein 4,SEC14-like protein 4,GO:0016021; GO:0005622; GO:0008289; GO:0005215,integral to membrane; intracellular; lipid binding; transporter activity,PF00650;,6.00E-13,CHOYP_SEC14L4.1.1,,,,,,,S14L4_MOUSE,Mus musculus (Mouse), comp129905_c0_seq3,769,44.7334,0.50519786,0,10,,6.00E-18,Q03606,CRAL-TRIO domain-containing protein T23G5.2,CRAL-TRIO domain-containing protein T23G5.2,GO:0016021; GO:0005622; GO:0005215,integral to membrane; intracellular; transporter activity,PF00650;PF03765;PF04707;,,,,,,,,,YN02_CAEEL,Caenorhabditis elegans, comp129907_c0_seq2,1418,41.8195,0.80987644,0,0,,1.00E-18,Q66T02,Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX),Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX),GO:0005089; GO:0005911; GO:0030139; GO:0035767; GO:0030027; GO:0048471; GO:0005543; GO:0005886; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell-cell junction; endocytic vesicle; endothelial cell chemotaxis; lamellipodium; perinuclear region of cytoplasm; phospholipid binding; plasma membrane; regulation of Rho protein signal transduction,PF00621;,5.00E-22,CHOYP_BRAFLDRAFT_124569.1.1,,,,,,,PKHG5_MOUSE,Mus musculus (Mouse),endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of Rho protein signal transduction [GO:0035023] comp129920_c0_seq1,737,35.8209,0.68018558,0,0,,,,,,,,,3.00E-21,CHOYP_LOC100642494.1.1,,,,,,,,, comp129920_c0_seq2,896,37.3884,0.68062666,7,9,,1.00E-58,Q3V384,Lactation elevated protein 1,Lactation elevated protein 1,GO:0005524; GO:0005739,ATP binding; mitochondrion,PF03969;,,,,,,,,,LACE1_MOUSE,Mus musculus (Mouse), comp129920_c0_seq3,801,36.3296,0.68618797,0,0,,9.00E-15,P32317,Protein AFG1,Protein AFG1,GO:0005524; GO:0034599; GO:0006515; GO:0005743; GO:0016558,ATP binding; cellular response to oxidative stress; misfolded or incompletely synthesized protein catabolic process; mitochondrial inner membrane; protein import into peroxisome matrix,PF03969;,,,,,,,,,AFG1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to oxidative stress [GO:0034599]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; protein import into peroxisome matrix [GO:0016558] comp129921_c1_seq1,766,39.0339,1.30828843,17,82,,1.00E-28,Q96D21,GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2),GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2),GO:0005525; GO:0003924; GO:0007626; GO:0031397; GO:0005886; GO:0051897; GO:0033235; GO:0043949; GO:0007264; GO:0001963,"GTP binding; GTPase activity; locomotory behavior; negative regulation of protein ubiquitination; plasma membrane; positive regulation of protein kinase B signaling cascade; positive regulation of protein sumoylation; regulation of cAMP-mediated signaling; small GTPase mediated signal transduction; synaptic transmission, dopaminergic",PF00071;,,,,,,,,,RHES_HUMAN,Homo sapiens (Human),"locomotory behavior [GO:0007626]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein sumoylation [GO:0033235]; regulation of cAMP-mediated signaling [GO:0043949]; small GTPase mediated signal transduction [GO:0007264]; synaptic transmission, dopaminergic [GO:0001963]" comp129923_c0_seq3,778,42.0308,0.46723724,15,19,,1.00E-29,Q9JK66,E3 ubiquitin-protein ligase parkin (EC 6.3.2.-),E3 ubiquitin-protein ligase parkin (EC 6.3.2.-),GO:0000139; GO:0006914; GO:0030054; GO:0005829; GO:0030425; GO:0005783; GO:0045121; GO:0005739; GO:0070997; GO:0042551; GO:0005634; GO:0014069; GO:0045211; GO:0070936; GO:0032403; GO:0006513; GO:0010506; GO:0051412; GO:0042493; GO:0006986; GO:0008021; GO:0006511; GO:0004842; GO:0008270,Golgi membrane; autophagy; cell junction; cytosol; dendrite; endoplasmic reticulum; membrane raft; mitochondrion; neuron death; neuron maturation; nucleus; postsynaptic density; postsynaptic membrane; protein K48-linked ubiquitination; protein complex binding; protein monoubiquitination; regulation of autophagy; response to corticosterone stimulus; response to drug; response to unfolded protein; synaptic vesicle; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF01485;PF00240;,,,,,,,,,PRKN2_RAT,Rattus norvegicus (Rat),"adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; cellular protein modification process [GO:0006464]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron cellular homeostasis [GO:0070050]; neuron maturation [GO:0042551]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA binding [GO:0043388]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of mitochondrion organization [GO:0010821]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]" comp129924_c0_seq1,751,43.1425,0.71638278,58,345,,6.00E-42,Q9N1F5,Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),GO:0019852; GO:0071243; GO:0005737; GO:0005829; GO:0045174; GO:0004364; GO:0050610; GO:0042178,L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; cytoplasm; cytosol; glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; methylarsonate reductase activity; xenobiotic catabolic process,PF14497;PF13417;,,,,,,,,,GSTO1_PIG,Sus scrofa (Pig),cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid metabolic process [GO:0019852]; xenobiotic catabolic process [GO:0042178] comp129924_c0_seq2,417,45.5635,0.833689,4,0,,9.00E-13,P81124,Probable glutathione transferase (EC 2.5.1.18) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (Protein 9) (Fragment),Probable glutathione transferase (EC 2.5.1.18) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (Protein 9) (Fragment),GO:0045174; GO:0004364; GO:0050610,glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; methylarsonate reductase activity,PF13417;,,,,,,,,,GSTO_APLCA,Aplysia californica (California sea hare), comp129929_c0_seq2,1964,41.4969,0.61408524,89,23,,,,,,,,,5.00E-74,CHOYP_LOC592357.1.1,,,,,,,,, comp129931_c1_seq1,368,35.0543,0.85417297,1,91,,5.00E-18,O43715,TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV),TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV),GO:0006977; GO:0034644; GO:0043027; GO:0005739; GO:1902166; GO:0048471; GO:0045944,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular response to UV; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; mitochondrion; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; perinuclear region of cytoplasm; positive regulation of transcription from RNA polymerase II promoter",PF05254;,,,,,,,,,TRIA1_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; phospholipid transport [GO:0015914]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of membrane lipid distribution [GO:0097035]" comp129934_c0_seq2,785,40.3822,0.45373651,0,0,,3.00E-08,P50411,Protein phosphatase inhibitor 2 (IPP-2),Protein phosphatase inhibitor 2 (IPP-2),GO:0005977; GO:0004864; GO:0043666; GO:0009966,glycogen metabolic process; protein phosphatase inhibitor activity; regulation of phosphoprotein phosphatase activity; regulation of signal transduction,PF04979;,9.00E-35,CHOYP_SET.1.1,,,,,,,IPP2_RAT,Rattus norvegicus (Rat),glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966] comp129936_c0_seq1,1033,40.9487,0.90372547,0,296,,7.00E-16,O44252,Protein rolling stone,Protein rolling stone,GO:0016021; GO:0016020; GO:0007520; GO:0007519,integral to membrane; membrane; myoblast fusion; skeletal muscle tissue development,,5.00E-14,CHOYP_NEMVEDRAFT_V1G181794.1.1,,,,,,,ROST_DROME,Drosophila melanogaster (Fruit fly),myoblast fusion [GO:0007520]; skeletal muscle tissue development [GO:0007519] comp129943_c2_seq1,809,42.398,0.28565427,59,66,,9.00E-67,Q58DR2,DnaJ homolog subfamily B member 12,DnaJ homolog subfamily B member 12,GO:0016021,integral to membrane,PF00226;PF09320;,1.00E-52,CHOYP_BRAFLDRAFT_209304.2.2,,,,,,,DJB12_BOVIN,Bos taurus (Bovine), comp129951_c1_seq2,1002,34.3313,0.40883193,2741,18,male>female,5.00E-36,A8Y5T1,Uncharacterized protein C1orf194 homolog,Uncharacterized protein C1orf194 homolog,,,PF12494;,1.00E-33,CHOYP_LOC100366787.1.1,3.00E-65,ruditapes2_c1712,,,,,CA194_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp129961_c1_seq1,2012,41.4016,0.97101718,6,1713,female>male,2.00E-60,P48430,Transcription factor SOX-2 (cSox2) (delta EF2a),Transcription factor SOX-2 (cSox2) (delta EF2a),GO:0007050; GO:0005829; GO:0001714; GO:0001654; GO:0048839; GO:0035198; GO:0090090; GO:0050680; GO:0045665; GO:0005634; GO:0001649; GO:0021983; GO:0043410; GO:0045944; GO:0043281; GO:0070848; GO:0009611; GO:0043565; GO:0003700; GO:0035019; GO:0044212; GO:0006351,"cell cycle arrest; cytosol; endodermal cell fate specification; eye development; inner ear development; miRNA binding; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of epithelial cell proliferation; negative regulation of neuron differentiation; nucleus; osteoblast differentiation; pituitary gland development; positive regulation of MAPK cascade; positive regulation of transcription from RNA polymerase II promoter; regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to growth factor stimulus; response to wounding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; somatic stem cell maintenance; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00505;PF12336;,1.00E-50,CHOYP_PHUM_PHUM361660.1.1,,,,,,,SOX2_CHICK,Gallus gallus (Chicken),"cell cycle arrest [GO:0007050]; endodermal cell fate specification [GO:0001714]; eye development [GO:0001654]; inner ear development [GO:0048839]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuron differentiation [GO:0045665]; osteoblast differentiation [GO:0001649]; pituitary gland development [GO:0021983]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; response to growth factor [GO:0070848]; response to wounding [GO:0009611]; sensory organ precursor cell fate determination [GO:0016360]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]" comp129962_c1_seq1,386,41.4508,1.05163749,2,76,,2.00E-08,Q9NZT1,Calmodulin-like protein 5 (Calmodulin-like skin protein),Calmodulin-like protein 5 (Calmodulin-like skin protein),GO:0005509; GO:0008544; GO:0007165,calcium ion binding; epidermis development; signal transduction,PF13499;,,,,,,,,,CALL5_HUMAN,Homo sapiens (Human),epidermis development [GO:0008544]; signal transduction [GO:0007165] comp129975_c0_seq1,874,37.4142,0.98870186,136,772,,4.00E-31,Q9D7X8,Gamma-glutamylcyclotransferase (EC 2.3.2.4),Gamma-glutamylcyclotransferase (EC 2.3.2.4),GO:0005829; GO:0003839; GO:0006750; GO:0042803; GO:0001836,cytosol; gamma-glutamylcyclotransferase activity; glutathione biosynthetic process; protein homodimerization activity; release of cytochrome c from mitochondria,,,,,,,,,,GGCT_MOUSE,Mus musculus (Mouse),glutathione biosynthetic process [GO:0006750]; release of cytochrome c from mitochondria [GO:0001836] comp129976_c1_seq3,924,42.8571,0.85244577,27,8,,,,,,,,,4.00E-34,CHOYP_LOC580601.5.5,,,,,,,,, comp129976_c2_seq1,240,39.1667,0.87280827,3,0,,3.00E-19,Q8NEM8,Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3),Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3),GO:0005829; GO:0004181; GO:0006508; GO:0008270,cytosol; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,,,,,,,,,CBPC3_HUMAN,Homo sapiens (Human),protein side chain deglutamylation [GO:0035610] comp129978_c0_seq1,364,46.4286,0.36067466,30,47,,6.00E-13,P00774,Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A),Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A),GO:0005576; GO:0006508; GO:0004252,extracellular region; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,CEL2A_RAT,Rattus norvegicus (Rat),establishment of skin barrier [GO:0061436] comp129980_c0_seq3,1101,42.5068,0.80450385,13,78,,4.00E-61,P28026,Protein Wnt-8 (XWnt-8),Protein Wnt-8 (XWnt-8),GO:0060061; GO:0044335; GO:0000578; GO:2000044; GO:0014034; GO:0051091; GO:0005578; GO:0044324,Spemann organizer formation; canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; embryonic axis specification; negative regulation of cardiac cell fate specification; neural crest cell fate commitment; positive regulation of sequence-specific DNA binding transcription factor activity; proteinaceous extracellular matrix; regulation of transcription involved in anterior/posterior axis specification,PF00110;,,,,,,,,,WNT8_XENLA,Xenopus laevis (African clawed frog),canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; embryonic axis specification [GO:0000578]; negative regulation of cardiac cell fate specification [GO:2000044]; neural crest cell fate commitment [GO:0014034]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of transcription involved in anterior/posterior axis specification [GO:0044324]; Spemann organizer formation [GO:0060061]; Wnt signaling pathway [GO:0016055] comp129981_c0_seq1,931,45.1128,0.78308747,33,17,,5.00E-07,Q14520,Hyaluronan-binding protein 2 (EC 3.4.21.-) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) (Hepatocyte growth factor activator-like protein) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form],Hyaluronan-binding protein 2 (EC 3.4.21.-) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) (Hepatocyte growth factor activator-like protein) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form],GO:0007155; GO:0005615; GO:0005539; GO:0006508; GO:0004252,cell adhesion; extracellular space; glycosaminoglycan binding; proteolysis; serine-type endopeptidase activity,PF00008;PF00051;PF00089;,,,,,,,,,HABP2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp129985_c0_seq1,1299,43.8799,0.37311592,10,17,,2.00E-129,O75800,Zinc finger MYND domain-containing protein 10 (Protein BLu),Zinc finger MYND domain-containing protein 10 (Protein BLu),GO:0005737; GO:0046872,cytoplasm; metal ion binding,PF01753;,,,,,2.00E-103,AM861092.p.cg.6,7,,ZMY10_HUMAN,Homo sapiens (Human),inner dynein arm assembly [GO:0036159]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158] comp129985_c0_seq2,1021,43.8786,0.3907675,0,3,,,,,,,,,3.00E-93,CHOYP_LOC576498.1.1,,,,,,,,, comp129985_c0_seq3,814,42.8747,0.35382768,0,0,,3.00E-06,Q3TPE9,Ankyrin repeat and MYND domain-containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,GO:0005929; GO:0046872,cilium; metal ion binding,PF12796;PF01753;,,,,,,,,,ANKY2_MOUSE,Mus musculus (Mouse), comp129990_c0_seq1,2024,40.6126,0.45967753,184,1197,,0,Q9DBA9,General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit),General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit),GO:0000439; GO:0005675; GO:0006289; GO:0006468; GO:0006355; GO:0006366,"core TFIIH complex; holo TFIIH complex; nucleotide-excision repair; protein phosphorylation; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF03909;PF08567;,3.00E-108,CHOYP_TF2H1.1.1,2.00E-20,ruditapes_c13075,,,,,TF2H1_MOUSE,Mus musculus (Mouse),nucleotide-excision repair [GO:0006289]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; transcription from RNA polymerase II promoter [GO:0006366] comp129991_c2_seq2,1429,43.6669,0.56493561,26,93,,0,Q8CG07,ATPase WRNIP1 (EC 3.6.1.3) (Werner helicase-interacting protein 1),ATPase WRNIP1 (EC 3.6.1.3) (Werner helicase-interacting protein 1),GO:0005524; GO:0016887; GO:0003677; GO:0006260; GO:0000731; GO:0046872; GO:0005739; GO:0005634; GO:0048471; GO:0030174,ATP binding; ATPase activity; DNA binding; DNA replication; DNA synthesis involved in DNA repair; metal ion binding; mitochondrion; nucleus; perinuclear region of cytoplasm; regulation of DNA-dependent DNA replication initiation,PF00004;PF16193;PF12002;,4.00E-42,CHOYP_LOC101169976.1.1,,,,,,,WRIP1_RAT,Rattus norvegicus (Rat),DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp129996_c0_seq1,767,44.4589,0.72276177,0,0,,1.00E-70,Q7ZWD4,UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-),UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-),GO:0016779,nucleotidyltransferase activity,PF01704;,9.00E-60,CHOYP_BRAFLDRAFT_125327.1.1,,,,,,,UAP1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp129996_c0_seq2,800,45.25,0.76639009,0,0,,7.00E-78,Q16222,UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83) (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (AGX-2)],UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83) (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (AGX-2)],GO:0006048; GO:0003977; GO:0030246; GO:0005829; GO:0006488; GO:0005634; GO:0005886; GO:0043687; GO:0018279,UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine diphosphorylase activity; carbohydrate binding; cytosol; dolichol-linked oligosaccharide biosynthetic process; nucleus; plasma membrane; post-translational protein modification; protein N-linked glycosylation via asparagine,PF01704;,,,,,,,,,UAP1_HUMAN,Homo sapiens (Human),UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp129997_c0_seq2,368,46.7391,0.89818107,9,86,,2.00E-15,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp129999_c0_seq1,1184,45.3547,0.93786515,5,2280,female>male,8.00E-24,Q70E20,"Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein)","Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein)",GO:0005509; GO:0007160; GO:0005576,calcium ion binding; cell-matrix adhesion; extracellular region,PF00008;PF00041;PF12661;PF06119;,,,,,,,,,SNED1_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160] comp130002_c0_seq1,1491,42.1865,0.50190648,42,54,,,,,,,,,3.00E-12,CHOYP_UBP47.2.2,,,,,,,,, comp130002_c0_seq2,935,40.8556,0.46551777,0,8,,,,,,,,,2.00E-43,CHOYP_UBP47.1.2,,,,,,,,, comp130002_c1_seq1,291,42.9553,0.6320421,10,13,,,,,,,,,1.00E-21,CHOYP_UBP47.2.2,,,,,,,,, comp130002_c2_seq1,775,42.1935,0.52665799,31,46,,1.00E-77,E1C1R4,Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47),Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47),GO:0006284; GO:0005737; GO:0035520; GO:0004221; GO:0006511; GO:0004843,base-excision repair; cytoplasm; monoubiquitinated protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF14560;PF00443;,2.00E-50,CHOYP_UBP47.1.2,,,,,,,UBP47_CHICK,Gallus gallus (Chicken),"base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp130010_c0_seq2,640,44.5312,0.56938552,30,52,,8.00E-55,P70470,Acyl-protein thioesterase 1 (APT-1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I),Acyl-protein thioesterase 1 (APT-1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I),GO:0005737; GO:0006631; GO:0004622; GO:0008474,cytoplasm; fatty acid metabolic process; lysophospholipase activity; palmitoyl-(protein) hydrolase activity,PF02230;,1.00E-31,CHOYP_LYPA2.1.1,,,,,,,LYPA1_RAT,Rattus norvegicus (Rat),fatty acid metabolic process [GO:0006631]; protein depalmitoylation [GO:0002084] comp130019_c0_seq1,1687,42.5608,0.44929481,0,0,,6.00E-37,Q92260,Heat shock 70 kDa protein (allergen Pen c 19) (Fragment),Heat shock 70 kDa protein (allergen Pen c 19) (Fragment),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,6.00E-104,CHOYP_HYOU1.2.3,,,,,,,HSP70_PENCI,Penicillium citrinum, comp130019_c0_seq3,2081,43.2004,0.45972076,0,0,,2.00E-94,F4JMJ1,Heat shock 70 kDa protein 17 (Heat shock protein 70-17) (AtHsp70-17),Heat shock 70 kDa protein 17 (Heat shock protein 70-17) (AtHsp70-17),GO:0005524; GO:0005794; GO:0009507; GO:0005783; GO:0005788; GO:0005774,ATP binding; Golgi apparatus; chloroplast; endoplasmic reticulum; endoplasmic reticulum lumen; vacuolar membrane,PF00012;,,,,,,,,,HSP7R_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp130019_c0_seq4,1810,42.5967,0.44400327,0,0,,1.00E-34,Q05558,Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70),Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70),GO:0005524; GO:0006457; GO:0006950,ATP binding; protein folding; response to stress,PF00012;,7.00E-104,CHOYP_HYOU1.2.3,6.00E-83,ruditapes2_c3002,,,,,DNAK_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),protein folding [GO:0006457] comp130019_c0_seq5,2204,43.1942,0.45492692,2,10,,0,Q7ZUW2,Hypoxia up-regulated protein 1,Hypoxia up-regulated protein 1,GO:0005524; GO:0005788,ATP binding; endoplasmic reticulum lumen,PF00012;,,,,,,,,,HYOU1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130032_c1_seq1,1132,44.3463,0.45750456,56,65,,6.00E-56,Q2TAW0,Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2),Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2),GO:0051301; GO:0030261; GO:0007067; GO:0005634,cell division; chromosome condensation; mitosis; nucleus,PF12422;,,,,,,,,,CNDG2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; chromosome condensation [GO:0030261]; mitotic nuclear division [GO:0007067] comp130035_c1_seq1,302,40.7285,0.88268976,1,39,,8.00E-33,Q9UBQ7,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0034641; GO:0007588; GO:0008465; GO:0046487; GO:0030267; GO:0016618; GO:0005782; GO:0042803; GO:0051259,NAD binding; NADPH binding; cellular nitrogen compound metabolic process; excretion; glycerate dehydrogenase activity; glyoxylate metabolic process; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; peroxisomal matrix; protein homodimerization activity; protein oligomerization,PF00389;PF02826;,,,3.00E-20,ruditapes_lrc35732,,,,,GRHPR_HUMAN,Homo sapiens (Human),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp130037_c0_seq1,932,43.3476,1.02128265,2,266,female>male,2.00E-66,Q9VNL4,Glutaredoxin domain-containing cysteine-rich protein CG31559,Glutaredoxin domain-containing cysteine-rich protein CG31559,GO:0045454; GO:0009055; GO:0015035,cell redox homeostasis; electron carrier activity; protein disulfide oxidoreductase activity,PF00462;,1.00E-34,CHOYP_DANA_GF18626.1.1,6.00E-36,ruditapes_c24367,,,,,GRCR1_DROME,Drosophila melanogaster (Fruit fly),cell redox homeostasis [GO:0045454] comp130038_c0_seq1,907,36.8247,0.653991,177,800,,6.00E-40,Q28G67,Protein FAM206A,Protein Simiate (Protein FAM206A),GO:0006546; GO:0005960,glycine catabolic process; glycine cleavage complex,PF01597;,,,,,,,,,F206A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp130044_c1_seq1,779,40.1797,0.23172944,62,31,,6.00E-07,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130055_c1_seq4,986,37.0183,0.87973605,10,8,,,,,,,,,3.00E-16,CHOYP_LOC587827.2.4,,,,,,,,, comp130059_c0_seq2,819,42.0024,0.83155991,0,9,,6.00E-10,P48055,Sodium- and chloride-dependent betaine transporter (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12),Sodium- and chloride-dependent betaine transporter (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12),GO:0005332; GO:0005887; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,S6A12_RABIT,Oryctolagus cuniculus (Rabbit), comp130059_c0_seq6,595,45.7143,0.74601571,0,35,,2.00E-27,P28571,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),GO:0015187; GO:0016021; GO:0005887; GO:0005328; GO:0005886; GO:0005283,glycine transmembrane transporter activity; integral to membrane; integral to plasma membrane; neurotransmitter:sodium symporter activity; plasma membrane; sodium:amino acid symporter activity,PF00209;,2.00E-17,CHOYP_SC6A5.3.7,8.00E-13,ruditapes2_c1123,,,,,SC6A9_MOUSE,Mus musculus (Mouse),"glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; glycine transport [GO:0015816]" comp130061_c0_seq2,416,45.4327,0.35042219,5,6,,8.00E-17,Q9UHC1,DNA mismatch repair protein Mlh3 (MutL protein homolog 3),DNA mismatch repair protein Mlh3 (MutL protein homolog 3),GO:0005524; GO:0016887; GO:0032390; GO:0032407; GO:0019237; GO:0005712; GO:0003682; GO:0007144; GO:0001673; GO:0007140; GO:0006298; GO:0030983; GO:0008104; GO:0007131; GO:0003696; GO:0003697; GO:0000795; GO:0007130,ATP binding; ATPase activity; MutLbeta complex; MutSalpha complex binding; centromeric DNA binding; chiasma; chromatin binding; female meiosis I; male germ cell nucleus; male meiosis; mismatch repair; mismatched DNA binding; protein localization; reciprocal meiotic recombination; satellite DNA binding; single-stranded DNA binding; synaptonemal complex; synaptonemal complex assembly,PF01119;PF08676;,,,,,,,,,MLH3_HUMAN,Homo sapiens (Human),female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] comp130061_c2_seq1,397,44.0806,0.46799356,21,13,,7.00E-20,Q9UHC1,DNA mismatch repair protein Mlh3 (MutL protein homolog 3),DNA mismatch repair protein Mlh3 (MutL protein homolog 3),GO:0005524; GO:0016887; GO:0032390; GO:0032407; GO:0019237; GO:0005712; GO:0003682; GO:0007144; GO:0001673; GO:0007140; GO:0006298; GO:0030983; GO:0008104; GO:0007131; GO:0003696; GO:0003697; GO:0000795; GO:0007130,ATP binding; ATPase activity; MutLbeta complex; MutSalpha complex binding; centromeric DNA binding; chiasma; chromatin binding; female meiosis I; male germ cell nucleus; male meiosis; mismatch repair; mismatched DNA binding; protein localization; reciprocal meiotic recombination; satellite DNA binding; single-stranded DNA binding; synaptonemal complex; synaptonemal complex assembly,PF01119;PF08676;,,,,,,,,,MLH3_HUMAN,Homo sapiens (Human),female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] comp130067_c0_seq1,791,38.8116,0.44147228,497,1807,,,,,,,,,4.00E-45,CHOYP_LOC100377460.1.1,,,,,,,,, comp130067_c0_seq2,735,37.0068,0.52367236,0,1,,2.00E-44,O73930,Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (cDcoH) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD),Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (cDcoH) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD),GO:0008124; GO:0005737; GO:0005634; GO:0004505; GO:0051291; GO:0051289; GO:0006355; GO:0006729; GO:0006351,"4-alpha-hydroxytetrahydrobiopterin dehydratase activity; cytoplasm; nucleus; phenylalanine 4-monooxygenase activity; protein heterooligomerization; protein homotetramerization; regulation of transcription, DNA-dependent; tetrahydrobiopterin biosynthetic process; transcription, DNA-dependent",PF01329;,4.00E-45,CHOYP_LOC100377460.1.1,,,,,,,PHS_CHICK,Gallus gallus (Chicken),"protein heterooligomerization [GO:0051291]; protein homotetramerization [GO:0051289]; regulation of transcription, DNA-templated [GO:0006355]; tetrahydrobiopterin biosynthetic process [GO:0006729]; transcription, DNA-templated [GO:0006351]" comp130067_c0_seq6,1396,35.6734,0.6539421,1,0,,6.00E-67,Q07460,Eukaryotic translation initiation factor 5A-2 (eIF-5A-2) (eIF-5A2) (Eukaryotic initiation factor 5A isoform 2) (eIF-4D),Eukaryotic translation initiation factor 5A-2 (eIF-5A-2) (eIF-5A2) (Eukaryotic initiation factor 5A isoform 2) (eIF-4D),GO:0005789; GO:0051028; GO:0005643; GO:0008612; GO:0008284; GO:0045901; GO:0045905; GO:0015031; GO:0043022; GO:0003746; GO:0006452,endoplasmic reticulum membrane; mRNA transport; nuclear pore; peptidyl-lysine modification to hypusine; positive regulation of cell proliferation; positive regulation of translational elongation; positive regulation of translational termination; protein transport; ribosome binding; translation elongation factor activity; translational frameshifting,PF01287;,2.00E-39,CHOYP_LOC100632169.4.6,3.00E-54,ruditapes_c769,,,,,IF5A2_CHICK,Gallus gallus (Chicken),mRNA transport [GO:0051028]; positive regulation of cell proliferation [GO:0008284]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; protein transport [GO:0015031]; translational frameshifting [GO:0006452] comp130067_c0_seq7,1409,32.8602,0.50757888,17284,92816,,2.00E-15,Q9DGK4,Translationally-controlled tumor protein homolog (TCTP),Translationally-controlled tumor protein homolog (TCTP),GO:0005737,cytoplasm,PF00838;,,,,,,,,,TCTP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130070_c0_seq13,1901,38.506,0.9381224,0,0,,,,,,,,,,,2.00E-32,ruditapes_c23837,,,,,,, comp130070_c0_seq17,2231,41.0578,0.94729633,0,11,,,,,,,,,,,5.00E-47,ruditapes2_c2884,,,,,,, comp130071_c0_seq1,733,38.1992,0.68417092,28,133,,2.00E-39,O75167,Phosphatase and actin regulator 2,Phosphatase and actin regulator 2,GO:0004864,protein phosphatase inhibitor activity,PF02755;,2.00E-43,CHOYP_KDM1A.1.1,,,,,,,PHAR2_HUMAN,Homo sapiens (Human),platelet degranulation [GO:0002576] comp130073_c0_seq1,271,50.9225,0.18391055,63,9,,,,,,,,,1.00E-13,CHOYP_LOC100929680.1.2,,,,,,,,, comp130073_c0_seq2,276,51.087,0.12410557,13,0,,,,,,,,,1.00E-13,CHOYP_LOC100929680.2.2,,,,,,,,, comp130074_c0_seq1,1253,38.1484,1.13008978,68,573,,4.00E-06,Q66J36,Nuclear factor interleukin-3-regulated protein,Nuclear factor interleukin-3-regulated protein,GO:0007623; GO:0005737; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"circadian rhythm; cytoplasm; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF07716;PF06529;,,,,,,,,,NFIL3_XENLA,Xenopus laevis (African clawed frog),circadian rhythm [GO:0007623]; immune response [GO:0006955]; transcription from RNA polymerase II promoter [GO:0006366] comp130076_c0_seq1,1656,39.1908,0.49515152,0,0,,7.00E-17,Q2MV58,Tectonic-1,Tectonic-1,GO:0036038; GO:0021956; GO:0060271; GO:0005737; GO:0021904; GO:0005615; GO:0001701; GO:0016020; GO:0005932; GO:0001841; GO:0008589; GO:0021523; GO:0021537,TCTN-B9D complex; central nervous system interneuron axonogenesis; cilium morphogenesis; cytoplasm; dorsal/ventral neural tube patterning; extracellular space; in utero embryonic development; membrane; microtubule basal body; neural tube formation; regulation of smoothened signaling pathway; somatic motor neuron differentiation; telencephalon development,PF07773;,,,,,,,,,TECT1_HUMAN,Homo sapiens (Human),central nervous system interneuron axonogenesis [GO:0021956]; cilium morphogenesis [GO:0060271]; dorsal/ventral neural tube patterning [GO:0021904]; in utero embryonic development [GO:0001701]; neural tube formation [GO:0001841]; regulation of smoothened signaling pathway [GO:0008589]; somatic motor neuron differentiation [GO:0021523]; telencephalon development [GO:0021537] comp130076_c0_seq2,1754,39.4527,0.4745369,6,15,,1.00E-21,Q2MV58,Tectonic-1,Tectonic-1,GO:0036038; GO:0021956; GO:0060271; GO:0005737; GO:0021904; GO:0005615; GO:0001701; GO:0016020; GO:0005932; GO:0001841; GO:0008589; GO:0021523; GO:0021537,TCTN-B9D complex; central nervous system interneuron axonogenesis; cilium morphogenesis; cytoplasm; dorsal/ventral neural tube patterning; extracellular space; in utero embryonic development; membrane; microtubule basal body; neural tube formation; regulation of smoothened signaling pathway; somatic motor neuron differentiation; telencephalon development,PF07773;,,,,,,,,,TECT1_HUMAN,Homo sapiens (Human),central nervous system interneuron axonogenesis [GO:0021956]; cilium morphogenesis [GO:0060271]; dorsal/ventral neural tube patterning [GO:0021904]; in utero embryonic development [GO:0001701]; neural tube formation [GO:0001841]; regulation of smoothened signaling pathway [GO:0008589]; somatic motor neuron differentiation [GO:0021523]; telencephalon development [GO:0021537] comp130078_c0_seq1,993,39.7784,0.48420724,544,2850,,4.00E-19,Q3MHY7,"39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10)","39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10)",GO:0005762; GO:0042254; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; ribosome biogenesis; structural constituent of ribosome; translation,PF00466;,,,,,,,,,RM10_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; ribosome biogenesis [GO:0042254]; translation [GO:0006412] comp130081_c0_seq1,1512,36.3095,0.56245378,1221,11492,,9.00E-57,Q1RMJ7,tRNA selenocysteine 1-associated protein 1 (tRNA selenocysteine-associated protein 1),tRNA selenocysteine 1-associated protein 1 (tRNA selenocysteine-associated protein 1),GO:0003723; GO:0005737; GO:0000166; GO:0005634; GO:0001514,RNA binding; cytoplasm; nucleotide binding; nucleus; selenocysteine incorporation,PF00076;,1.00E-16,CHOYP_TSAP1.2.2,,,,,,,TSAP1_BOVIN,Bos taurus (Bovine),selenocysteine incorporation [GO:0001514] comp130084_c1_seq1,539,48.2375,0.76759326,14,58,,6.00E-13,Q8K4Q7,Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase),Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase),GO:0005524; GO:0003951; GO:0001729; GO:0006672; GO:0004143; GO:0016021; GO:0000287; GO:0005739; GO:0005634; GO:0007205,ATP binding; NAD+ kinase activity; ceramide kinase activity; ceramide metabolic process; diacylglycerol kinase activity; integral to membrane; magnesium ion binding; mitochondrion; nucleus; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00781;,,,,,,,,,CERK1_MOUSE,Mus musculus (Mouse),ceramide metabolic process [GO:0006672] comp130085_c0_seq2,887,43.5175,0.40580697,18,51,,2.00E-41,Q8TDM6,Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),GO:0008013; GO:0005913; GO:0016337; GO:0005737; GO:0008092; GO:0035556; GO:0008285; GO:0005886; GO:0030159; GO:0042981,beta-catenin binding; cell-cell adherens junction; cell-cell adhesion; cytoplasm; cytoskeletal protein binding; intracellular signal transduction; negative regulation of cell proliferation; plasma membrane; receptor signaling complex scaffold activity; regulation of apoptotic process,PF00625;PF00595;PF04822;,2.00E-61,CHOYP_DLG5A.1.1,,,,,,,DLG5_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186] comp130086_c0_seq1,633,32.5434,0.95626181,0,183,,2.00E-06,Q6DKJ4,Nucleoredoxin (EC 1.8.1.8),Nucleoredoxin (EC 1.8.1.8),GO:0016055; GO:0072358; GO:0030154; GO:0005829; GO:0030178; GO:0031397; GO:0005634; GO:0047134; GO:0004791,Wnt receptor signaling pathway; cardiovascular system development; cell differentiation; cytosol; negative regulation of Wnt receptor signaling pathway; negative regulation of protein ubiquitination; nucleus; protein-disulfide reductase activity; thioredoxin-disulfide reductase activity,PF13905;,,,,,,,,,NXN_HUMAN,Homo sapiens (Human),cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp130088_c0_seq1,947,38.6484,0.58288309,6,8,,1.00E-51,Q1LZ74,O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-),O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-),GO:0019213; GO:0001883; GO:0042278,deacetylase activity; purine nucleoside binding; purine nucleoside metabolic process,PF01661;,,,,,,,,,CF130_BOVIN,Bos taurus (Bovine),purine nucleoside metabolic process [GO:0042278] comp130088_c0_seq2,993,39.3756,0.53587849,14,50,,3.00E-53,Q9Y530,O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-),O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-),GO:0019213; GO:0001883; GO:0042278,deacetylase activity; purine nucleoside binding; purine nucleoside metabolic process,PF01661;,,,,,,,,,CF130_HUMAN,Homo sapiens (Human),purine nucleoside metabolic process [GO:0042278] comp130089_c0_seq1,795,39.4969,0.49410382,107,399,,3.00E-13,Q9HBM1,Kinetochore protein Spc25 (hSpc25),Kinetochore protein Spc25 (hSpc25),GO:0031262; GO:0051301; GO:0007059; GO:0000777; GO:0005829; GO:0007067; GO:0007052; GO:0005634,Ndc80 complex; cell division; chromosome segregation; condensed chromosome kinetochore; cytosol; mitosis; mitotic spindle organization; nucleus,PF08234;,,,,,,,,,SPC25_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; sister chromatid cohesion [GO:0007062] comp130090_c0_seq1,918,41.0675,0.74112991,87,1091,,5.00E-15,P82596,Perlucin,Perlucin,GO:0030246,carbohydrate binding,PF00059;,,,,,,,,,PLC_HALLA,Haliotis laevigata (Abalone), comp130095_c0_seq2,665,41.8045,0.58675506,17,31,,2.00E-12,Q9JMG2,"C1GALT1-specific chaperone 1 (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (mC1Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone)","C1GALT1-specific chaperone 1 (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (mC1Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone)",GO:0016021,integral to membrane,,,,,,,,,,C1GLC_MOUSE,Mus musculus (Mouse),"O-glycan processing, core 1 [GO:0016267]; platelet activation [GO:0030168]; platelet morphogenesis [GO:0036344]; protein O-linked glycosylation [GO:0006493]" comp130095_c0_seq3,458,48.4716,0.7106455,15,7,,2.00E-55,Q7K237,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)",GO:0016267; GO:0021551; GO:0009247; GO:0016263; GO:0016021; GO:0046872,"O-glycan processing, core 1; central nervous system morphogenesis; glycolipid biosynthetic process; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; metal ion binding",PF02434;,2.00E-27,CHOYP_AGAP_AGAP009979.1.1,,,,,,,C1GLT_DROME,Drosophila melanogaster (Fruit fly),"central nervous system morphogenesis [GO:0021551]; glycolipid biosynthetic process [GO:0009247]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; O-glycan processing, core 1 [GO:0016267]; protein glycosylation [GO:0006486]; regulation of filopodium assembly [GO:0051489]" comp130098_c1_seq1,792,49.6212,0.70596049,0,0,,5.00E-74,Q9UQ26,Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3),Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3),GO:0019933; GO:0017156; GO:0048791; GO:0030054; GO:0030073; GO:0006886; GO:0046872; GO:0042734; GO:0017157; GO:0042391,cAMP-mediated signaling; calcium ion-dependent exocytosis; calcium ion-dependent exocytosis of neurotransmitter; cell junction; insulin secretion; intracellular protein transport; metal ion binding; presynaptic membrane; regulation of exocytosis; regulation of membrane potential,PF00168;PF02318;,1.00E-109,CHOYP_RIMS2.2.3,,,,,,,RIMS2_HUMAN,Homo sapiens (Human),calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669] comp130098_c1_seq2,1657,49.6077,0.7286097,1,0,,5.00E-83,Q9JIS1,Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2),Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2),GO:0030054; GO:0006887; GO:0006886; GO:0046872; GO:0006836; GO:0042734,cell junction; exocytosis; intracellular protein transport; metal ion binding; neurotransmitter transport; presynaptic membrane,PF00168;PF02318;,,,,,,,,,RIMS2_RAT,Rattus norvegicus (Rat),calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; cell differentiation [GO:0030154]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669] comp130098_c1_seq3,516,47.4806,0.73378216,0,0,,5.00E-12,P41823,Synaptotagmin-1 (Synaptotagmin I) (p65),Synaptotagmin-1 (Synaptotagmin I) (p65),GO:0000149; GO:0005509; GO:0030054; GO:0030285; GO:0045955; GO:0016079; GO:0005215,SNARE binding; calcium ion binding; cell junction; integral to synaptic vesicle membrane; negative regulation of calcium ion-dependent exocytosis; synaptic vesicle exocytosis; transporter activity,PF00168;,,,,,,,,,SY65_APLCA,Aplysia californica (California sea hare),negative regulation of calcium ion-dependent exocytosis [GO:0045955]; synaptic vesicle exocytosis [GO:0016079] comp130098_c1_seq5,804,49.5025,0.71948528,0,0,,9.00E-76,Q9JIS1,Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2),Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2),GO:0030054; GO:0006887; GO:0006886; GO:0046872; GO:0006836; GO:0042734,cell junction; exocytosis; intracellular protein transport; metal ion binding; neurotransmitter transport; presynaptic membrane,PF00168;PF02318;,,,,,,,,,RIMS2_RAT,Rattus norvegicus (Rat),calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; cell differentiation [GO:0030154]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669] comp130100_c1_seq1,2454,30.5216,0.35657232,1850,4976,,,,,,,,,,,3.00E-19,ruditapes_c1779,,,,,,, comp130101_c0_seq1,1503,45.9747,0.44682135,20,42,,4.00E-148,A6QQP7,Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1),Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1),GO:0030659; GO:0016021; GO:0042383; GO:0006906,cytoplasmic vesicle membrane; integral to membrane; sarcolemma; vesicle fusion,PF00168;PF08165;PF08150;PF08151;PF16165;,2.00E-134,CHOYP_MYOF.3.3,,,,,,,DYSF_BOVIN,Bos taurus (Bovine),vesicle fusion [GO:0006906] comp130101_c0_seq2,1151,44.8306,0.49215783,0,3,,,,,,,,,2.00E-31,CHOYP_LOC724747.1.1,,,,,,,,, comp130104_c0_seq3,226,33.6283,0.15819125,4,24,,,,,,,,,1.00E-12,CHOYP_contig_011728,,,,,,,,, comp130106_c2_seq1,645,45.5814,0.55689789,0,4,,2.00E-16,Q03203,Nisin transport ATP-binding protein NisT,Nisin transport ATP-binding protein NisT,GO:0005524; GO:0006200; GO:0042626; GO:0043213; GO:0016021; GO:0005886; GO:0015031,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; bacteriocin transport; integral to membrane; plasma membrane; protein transport",PF00005;,,,,,,,,,NIST_LACLL,Lactococcus lactis subsp. lactis (Streptococcus lactis),bacteriocin transport [GO:0043213]; protein transport [GO:0015031] comp130106_c2_seq2,236,40.2542,0.95055183,3,21,,7.00E-07,P16877,Multidrug resistance protein 4 (P-glycoprotein) (Fragment),Multidrug resistance protein 4 (P-glycoprotein) (Fragment),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF00005;,4.00E-13,CHOYP_ABCB6.3.3,,,,,,,MDR4_ENTHI,Entamoeba histolytica,transport [GO:0006810] comp130106_c2_seq3,645,45.2713,0.57126151,0,15,,3.00E-48,Q08D64,"ATP-binding cassette sub-family B member 6, mitochondrial","ATP-binding cassette sub-family B member 6, mitochondrial",GO:0005524; GO:0006200; GO:0042626; GO:0005794; GO:0005783; GO:0016021; GO:0005741; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; Golgi apparatus; endoplasmic reticulum; integral to membrane; mitochondrial outer membrane; plasma membrane",PF00664;PF00005;PF16185;,2.00E-34,CHOYP_ABCB6.1.3,,,,,,,ABCB6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp130107_c0_seq1,1558,42.1694,0.29565164,15,98,,4.00E-31,P38344,Cytoplasmic 60S subunit biogenesis factor REI1 (Required for isotropic bud growth protein 1) (pre-60S factor REI1),Cytoplasmic 60S subunit biogenesis factor REI1 (Required for isotropic bud growth protein 1) (pre-60S factor REI1),GO:0007117; GO:0005737; GO:0046872; GO:0000278; GO:0006913; GO:0030687; GO:0042273,"budding cell bud growth; cytoplasm; metal ion binding; mitotic cell cycle; nucleocytoplasmic transport; preribosome, large subunit precursor; ribosomal large subunit biogenesis",PF12756;,,,,,,,,,REI1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),budding cell bud growth [GO:0007117]; mitotic cell cycle [GO:0000278]; nucleocytoplasmic transport [GO:0006913]; ribosomal large subunit biogenesis [GO:0042273] comp130107_c0_seq2,1531,42.3906,0.29819964,17,175,,6.00E-66,Q91VY9,Zinc finger protein 622,Zinc finger protein 622,GO:0005794; GO:0008631; GO:0003676; GO:0005730; GO:0046330; GO:0043065; GO:0033674; GO:0008270,Golgi apparatus; intrinsic apoptotic signaling pathway in response to oxidative stress; nucleic acid binding; nucleolus; positive regulation of JNK cascade; positive regulation of apoptotic process; positive regulation of kinase activity; zinc ion binding,PF12756;,7.00E-52,CHOYP_ZN622.1.1,,,,,,,ZN622_MOUSE,Mus musculus (Mouse),intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273] comp130110_c0_seq1,1327,37.0761,0.47092225,5,16,,,,,,,,,2.00E-33,CHOYP_LOC100074304.1.1,,,,,,,,, comp130110_c0_seq2,1226,36.7863,0.37223955,0,0,,1.00E-77,Q32KL4,Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B),Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B),GO:0005737; GO:0005874; GO:0000922,cytoplasm; microtubule; spindle pole,,2.00E-33,CHOYP_LOC100074304.1.1,,,,,,,RMD1_BOVIN,Bos taurus (Bovine), comp130116_c1_seq1,273,40.6593,0.72487745,25,100,,,,,,,,,,,1.00E-11,ruditapes_lrc6950,,,,,,, comp130116_c1_seq2,2947,37.1904,0.65182791,45932,203750,,5.00E-13,Q04832,DNA-binding protein HEXBP (Hexamer-binding protein),DNA-binding protein HEXBP (Hexamer-binding protein),GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,PF00098;,5.00E-19,CHOYP_contig_045965,2.00E-22,ruditapes_c21807,,,,,HEXP_LEIMA,Leishmania major, comp130119_c0_seq1,610,39.0164,0.34578474,3,0,,1.00E-13,Q8G4U8,Maf-like/Nudix hydrolase fusion protein BL1276,Maf-like/Nudix hydrolase fusion protein BL1276,GO:0005737; GO:0016787,cytoplasm; hydrolase activity,PF02545;PF00293;,2.00E-22,CHOYP_LOC100378818.2.2,,,,,,,Y1276_BIFLO,Bifidobacterium longum (strain NCC 2705), comp130119_c0_seq3,757,37.5165,0.48871781,19,130,,3.00E-64,O95671,N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-),N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-),GO:0008171; GO:0005737,O-methyltransferase activity; cytoplasm,PF16864;PF02545;PF00891;,,,8.00E-46,ruditapes_c7987,,,,,ASML_HUMAN,Homo sapiens (Human), comp130127_c1_seq2,594,38.0471,0.65420746,20,40,,,,,,,,,,,1.00E-16,ruditapes_c14944,,,,,,, comp130130_c0_seq1,1253,38.8667,0.41386165,44,304,,6.00E-123,Q6GQN8,"Trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38)","Trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38)",GO:0006633; GO:0005739; GO:0039020; GO:0019166; GO:0008270,fatty acid biosynthetic process; mitochondrion; pronephric nephron tubule development; trans-2-enoyl-CoA reductase (NADPH) activity; zinc ion binding,PF08240;PF00107;,2.00E-26,CHOYP_MECR.1.1,,,,,,,MECR_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid biosynthetic process [GO:0006633]; pronephric nephron tubule development [GO:0039020] comp130130_c0_seq2,309,36.8932,0.28659776,0,0,,4.00E-06,Q9V6U9,"Probable trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38)","Probable trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38)",GO:0006633; GO:0006631; GO:0005875; GO:0005739; GO:0019166; GO:0008270,fatty acid biosynthetic process; fatty acid metabolic process; microtubule associated complex; mitochondrion; trans-2-enoyl-CoA reductase (NADPH) activity; zinc ion binding,PF08240;PF00107;,,,,,,,,,MECR_DROME,Drosophila melanogaster (Fruit fly),fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631] comp130132_c0_seq1,1091,40.2383,1.06818272,72,233,,4.00E-07,Q63931,Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R),Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R),GO:0004951; GO:0038188; GO:0016021; GO:0005886,cholecystokinin receptor activity; cholecystokinin signaling pathway; integral to membrane; plasma membrane,PF00001;PF09193;,,,,,,,,,CCKAR_CAVPO,Cavia porcellus (Guinea pig), comp130136_c0_seq1,765,41.3072,0.77719289,13,161,,4.00E-52,P07290,"Myosin, essential light chain, adductor muscle (Sulfhydryl light chain) (SHLC)","Myosin, essential light chain, adductor muscle (Sulfhydryl light chain) (SHLC)",GO:0005509; GO:0016459,calcium ion binding; myosin complex,PF13499;,1.00E-19,CHOYP_MLE.9.9,2.00E-35,ruditapes2_c281,,,,,MLE_MIZYE,Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis), comp130138_c0_seq1,927,42.3948,0.60085018,463,2413,,1.00E-125,Q0P457,Protein KTI12 homolog,Protein KTI12 homolog,GO:0005524,ATP binding,PF08433;,4.00E-40,CHOYP_KTI12.1.1,1.00E-68,ruditapes_c28872,,,,,KTI12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130146_c0_seq1,897,38.6845,0.300717,9,35,,3.00E-06,Q9UBT6,DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP),DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP),GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0046872; GO:0006297; GO:0005634,"DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; metal ion binding; nucleotide-excision repair, DNA gap filling; nucleus",PF00817;PF11799;PF11798;,,,,,,,,,POLK_HUMAN,Homo sapiens (Human),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp130148_c0_seq1,1549,43.4474,0.37678957,28,45,,2.00E-87,P58854,Gamma-tubulin complex component 3 (GCP-3),Gamma-tubulin complex component 3 (GCP-3),GO:0005814; GO:0007020; GO:0005827,centriole; microtubule nucleation; polar microtubule,PF04130;,9.00E-108,CHOYP_BRAFLDRAFT_278559.1.1,,,,,,,GCP3_MOUSE,Mus musculus (Mouse),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; mitotic spindle assembly [GO:0090307] comp130148_c0_seq2,1124,41.726,0.39730515,4,0,,2.00E-34,Q95ZG4,Spindle pole body component 98 (DdSpc98) (Spc98),Spindle pole body component 98 (DdSpc98) (Spc98),GO:0005813; GO:0005737; GO:0043015; GO:0005874; GO:0007020; GO:0000922,centrosome; cytoplasm; gamma-tubulin binding; microtubule; microtubule nucleation; spindle pole,PF04130;,4.00E-41,CHOYP_EF-1A.9.9,,,,,,,SPC98_DICDI,Dictyostelium discoideum (Slime mold),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; mitotic spindle assembly [GO:0090307] comp130149_c0_seq1,797,35.3827,0.36241668,278,1301,,5.00E-08,Q1LWG3,"39S ribosomal protein L36, mitochondrial (L36mt) (MRP-L36)","39S ribosomal protein L36, mitochondrial (L36mt) (MRP-L36)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF00444;,,,,,,,,,RM36_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ribosome biogenesis [GO:0042254]; translation [GO:0006412] comp130154_c0_seq1,784,45.1531,0.32658143,0,0,,2.00E-13,Q5XIP4,Ubiquilin-like protein,Ubiquilin-like protein,,,PF00240;,,,,,,,,,UBQLN_RAT,Rattus norvegicus (Rat), comp130154_c0_seq2,1987,44.7408,0.29283117,94,186,,4.00E-134,Q9UMX0,Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1),Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1),GO:0071456; GO:0005783; GO:0097194; GO:0005634; GO:0048471; GO:0000502; GO:0043234; GO:0031396; GO:0034976,cellular response to hypoxia; endoplasmic reticulum; execution phase of apoptosis; nucleus; perinuclear region of cytoplasm; proteasome complex; protein complex; regulation of protein ubiquitination; response to endoplasmic reticulum stress,PF00627;PF00240;,2.00E-118,CHOYP_UBQL4.1.1,,,,,,,UBQL1_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; macroautophagy [GO:0016236]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976] comp130155_c0_seq1,1063,40.6397,0.39138842,469,1254,,7.00E-17,Q5U1W4,Lysosomal-associated transmembrane protein 4B,Lysosomal-associated transmembrane protein 4B,GO:0012505; GO:0016021; GO:0006810,endomembrane system; integral to membrane; transport,PF03821;,,,5.00E-37,ruditapes_c20403,,,,,LAP4B_RAT,Rattus norvegicus (Rat),transport [GO:0006810] comp130163_c2_seq1,783,44.8276,0.28192266,26,0,,9.00E-63,Q3TZZ7,Extended synaptotagmin-2 (E-Syt2),Extended synaptotagmin-2 (E-Syt2),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00168;PF17047;,4.00E-52,CHOYP_AAEL_AAEL009169.1.1,,,,,,,ESYT2_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; lipid transport [GO:0006869] comp130163_c2_seq2,585,44.9573,0.30987165,0,3,,3.00E-20,B6ETT4,Synaptotagmin-2 (NTMC2T1.2) (Synaptotagmin B),Synaptotagmin-2 (NTMC2T1.2) (Synaptotagmin B),GO:0005794; GO:0000139; GO:0016021; GO:0008289; GO:0046872; GO:0009306,Golgi apparatus; Golgi membrane; integral to membrane; lipid binding; metal ion binding; protein secretion,PF00168;PF17047;,3.00E-45,CHOYP_AAEL_AAEL009169.1.1,,,,,,,SYT2_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein secretion [GO:0009306] comp130168_c0_seq1,1093,39.7072,1.14036004,46,197,,2.00E-35,O75715,Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5),Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5),GO:0005576; GO:0004602; GO:0006629; GO:0006979,extracellular region; glutathione peroxidase activity; lipid metabolic process; response to oxidative stress,PF00255;,,,6.00E-74,ruditapes2_c380,,,,,GPX5_HUMAN,Homo sapiens (Human),cellular response to oxidative stress [GO:0034599]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302] comp130173_c0_seq1,1475,37.1525,0.62485178,8,14,,7.00E-39,O43581,Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII),Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII),GO:0005509; GO:0030054; GO:0016021; GO:0005764; GO:0005886; GO:0001778; GO:0017158; GO:0050796; GO:0030672; GO:0005215,calcium ion binding; cell junction; integral to membrane; lysosome; plasma membrane; plasma membrane repair; regulation of calcium ion-dependent exocytosis; regulation of insulin secretion; synaptic vesicle membrane; transporter activity,PF00168;,5.00E-54,CHOYP_SYT7.1.1,,,,,,,SYT7_HUMAN,Homo sapiens (Human),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle fusion [GO:0006906]; vesicle-mediated cholesterol transport [GO:0090119] comp130173_c0_seq2,1460,37.0548,0.6141755,0,4,,1.00E-14,Q925B4,Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII),Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII),GO:0001669; GO:0030276; GO:0016021; GO:0005886; GO:0008021; GO:0005215,acrosomal vesicle; clathrin binding; integral to membrane; plasma membrane; synaptic vesicle; transporter activity,PF00168;,4.00E-49,CHOYP_SYT7.1.1,,,,,,,SYT8_RAT,Rattus norvegicus (Rat),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906] comp130175_c1_seq1,1365,45.348,0.38672559,0,0,,1.00E-08,O30409,Tyrocidine synthase 3 (Tyrocidine synthase III) [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)],Tyrocidine synthase 3 (Tyrocidine synthase III) [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)],GO:0017000; GO:0016788; GO:0016874; GO:0031177,"antibiotic biosynthetic process; hydrolase activity, acting on ester bonds; ligase activity; phosphopantetheine binding",PF00501;PF13193;PF00668;PF00550;PF00975;,,,,,,,,,TYCC_BREPA,Brevibacillus parabrevis,antibiotic biosynthetic process [GO:0017000] comp130175_c1_seq2,2416,44.495,0.40655166,66,168,,0,Q9QUJ7,Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4),Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4),GO:0005524; GO:0047676; GO:0060996; GO:0060136; GO:0005789; GO:0015908; GO:0016021; GO:0008610; GO:0005811; GO:0004467; GO:0005741; GO:0005739; GO:0032307; GO:0030182; GO:0043025; GO:0005778; GO:0030307; GO:0019217; GO:0070672; GO:0007584; GO:0006641; GO:0031957,ATP binding; arachidonate-CoA ligase activity; dendritic spine development; embryonic process involved in female pregnancy; endoplasmic reticulum membrane; fatty acid transport; integral to membrane; lipid biosynthetic process; lipid particle; long-chain fatty acid-CoA ligase activity; mitochondrial outer membrane; mitochondrion; negative regulation of prostaglandin secretion; neuron differentiation; neuronal cell body; peroxisomal membrane; positive regulation of cell growth; regulation of fatty acid metabolic process; response to interleukin-15; response to nutrient; triglyceride metabolic process; very long-chain fatty acid-CoA ligase activity,PF00501;,1.00E-133,CHOYP_ACSL4.1.1,,,,,,,ACSL4_MOUSE,Mus musculus (Mouse),dendritic spine development [GO:0060996]; embryonic process involved in female pregnancy [GO:0060136]; fatty acid transport [GO:0015908]; lipid biosynthetic process [GO:0008610]; lipid metabolic process [GO:0006629]; negative regulation of prostaglandin secretion [GO:0032307]; neuron differentiation [GO:0030182]; positive regulation of cell growth [GO:0030307]; regulation of fatty acid metabolic process [GO:0019217]; response to interleukin-15 [GO:0070672]; response to nutrient [GO:0007584]; triglyceride metabolic process [GO:0006641] comp130180_c0_seq1,415,45.3012,0.42377156,6,77,,3.00E-17,Q9P2F8,Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),GO:0005096; GO:0043547; GO:0051056,GTPase activator activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction,PF02145;PF11881;,3.00E-18,CHOYP_SI1L1.2.2,,,,,,,SI1L2_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056] comp130180_c2_seq1,2195,49.1572,0.42251091,62,226,,2.00E-62,Q80TE4,Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),GO:0005096; GO:0043547; GO:0051056,GTPase activator activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction,PF02145;PF11881;,,,,,,,,,SI1L2_MOUSE,Mus musculus (Mouse),regulation of small GTPase mediated signal transduction [GO:0051056] comp130190_c0_seq1,1275,38.9804,0.31324689,123,319,,4.00E-103,A9UMG5,Protein IMPACT-B (Imprinted and ancient gene protein homolog B),Protein IMPACT-B (Imprinted and ancient gene protein homolog B),GO:0006417,regulation of translation,PF05773;PF01205;,,,,,,,,,IMPTB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733] comp130190_c0_seq2,1095,37.2603,0.34802179,49,99,,9.00E-64,O55091,Protein IMPACT (Imprinted and ancient gene protein),Protein IMPACT (Imprinted and ancient gene protein),GO:0005737; GO:0001933; GO:0006446,cytoplasm; negative regulation of protein phosphorylation; regulation of translational initiation,PF05773;PF01205;,4.00E-15,CHOYP_IMPACT.1.1,,,,,,,IMPCT_MOUSE,Mus musculus (Mouse),cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of translational initiation [GO:0006446] comp130191_c1_seq1,2618,47.2498,0.77604692,130,32,,2.00E-17,P85171,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,,,,,,,,,MDGA1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp130191_c1_seq2,644,41.9255,1.02724175,0,0,,2.00E-12,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp130199_c0_seq2,877,41.049,0.68431315,17,40,,8.00E-33,Q19546,Probable Werner syndrome ATP-dependent helicase homolog 1 (EC 3.6.4.12),Probable Werner syndrome ATP-dependent helicase homolog 1 (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0005694; GO:0008340; GO:0040007; GO:0005654; GO:0010212,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA binding; DNA recombination; DNA repair; DNA replication; chromosome; determination of adult lifespan; growth; nucleoplasm; response to ionizing radiation,PF00270;PF00271;PF00570;PF14493;PF16124;PF09382;,,,,,,,,,WRN_CAEEL,Caenorhabditis elegans,base-excision repair [GO:0006284]; cell aging [GO:0007569]; cellular response to gamma radiation [GO:0071480]; determination of adult lifespan [GO:0008340]; DNA metabolic process [GO:0006259]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; growth [GO:0040007]; replication fork processing [GO:0031297]; response to ionizing radiation [GO:0010212]; telomere maintenance via recombination [GO:0000722] comp130201_c0_seq1,499,41.0822,0.47646465,9,31,,,,,,,,,9.00E-26,CHOYP_LOC101172267.1.1,9.00E-49,ruditapes_c12533,,,,,,, comp130201_c0_seq2,765,42.6144,0.34598072,18,42,,9.00E-46,Q9NW38,E3 ubiquitin-protein ligase FANCL (EC 6.3.2.-) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43),E3 ubiquitin-protein ligase FANCL (EC 6.3.2.-) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43),GO:0006281; GO:0043240; GO:0005737; GO:0007276; GO:0005635; GO:0006513; GO:0042127; GO:0004842; GO:0008270,DNA repair; Fanconi anaemia nuclear complex; cytoplasm; gamete generation; nuclear envelope; protein monoubiquitination; regulation of cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF11793;PF09765;,,,,,,,,,FANCL_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; positive regulation of defense response to virus by host [GO:0002230]; protein monoubiquitination [GO:0006513]; regulation of cell proliferation [GO:0042127]; xenophagy [GO:0098792] comp130207_c0_seq2,356,45.7865,1.02773538,6,44,,4.00E-06,Q99PP7,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0070412; GO:0070410; GO:0016874; GO:0030514; GO:0005634; GO:0016567; GO:0006355; GO:0017015; GO:0006351; GO:0008270,"DNA binding; R-SMAD binding; co-SMAD binding; ligase activity; negative regulation of BMP signaling pathway; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; regulation of transforming growth factor beta receptor signaling pathway; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_MOUSE,Mus musculus (Mouse),"negative regulation of BMP signaling pathway [GO:0030514]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]" comp130208_c0_seq1,1206,36.9818,0.31630001,1104,8972,,2.00E-37,Q6GL69,MKI67 FHA domain-interacting nucleolar phosphoprotein-like,MKI67 FHA domain-interacting nucleolar phosphoprotein-like,GO:0003723; GO:0010923; GO:0005730; GO:0000166,RNA binding; negative regulation of phosphatase activity; nucleolus; nucleotide binding,PF12196;PF00076;,,,,,,,,,MK67I_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),negative regulation of phosphatase activity [GO:0010923] comp130214_c0_seq2,590,43.2203,0.2545227,18,73,,2.00E-36,A4FVI0,Zinc finger SWIM domain-containing protein 7,Zinc finger SWIM domain-containing protein 7,GO:0000724; GO:0005634; GO:0008270,double-strand break repair via homologous recombination; nucleus; zinc ion binding,PF04434;,2.00E-16,CHOYP_LOC100078233.1.1,,,,,,,ZSWM7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),double-strand break repair via homologous recombination [GO:0000724] comp130216_c0_seq1,954,39.0985,0.5780878,76,339,,2.00E-77,Q502G2,Transmembrane protein 41A-A,Transmembrane protein 41A-A,GO:0016021,integral to membrane,PF09335;,3.00E-54,CHOYP_LOC100181666.1.1,,,,,,,T41AA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130218_c0_seq2,1276,45.5329,0.6426316,53,42,,9.00E-88,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,,,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp130218_c1_seq1,1039,47.4495,0.32666587,0,7,,8.00E-11,Q55EI3,Putative vacuolar protein sorting-associated protein 13E,Putative vacuolar protein sorting-associated protein 13E,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF12624;PF06650;PF16908;PF16909;PF16910;,9.00E-11,CHOYP_VPS13D.1.1,,,,,,,VP13E_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp130218_c1_seq2,2639,47.6317,0.38124584,151,20,,0,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,9.00E-73,CHOYP_VP13D.1.3,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp130220_c0_seq1,1109,42.0198,0.77787062,0,4,,1.00E-11,Q8N2E2,von Willebrand factor D and EGF domain-containing protein,von Willebrand factor D and EGF domain-containing protein,GO:0005576,extracellular region,PF12661;PF00094;,,,,,,,,,VWDE_HUMAN,Homo sapiens (Human), comp130229_c0_seq1,1370,39.1971,0.66560819,36,0,,1.00E-15,Q8NEG2,Uncharacterized protein C7orf57,Uncharacterized protein C7orf57,,,,,,,,,,,,CG057_HUMAN,Homo sapiens (Human), comp130231_c0_seq1,1703,39.3423,0.44036516,71,1805,,1.00E-09,Q90W33,Hypermethylated in cancer 2 protein,Hypermethylated in cancer 2 protein,GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00651;PF00096;,,,,,,,,,HIC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130232_c0_seq1,1391,35.9454,0.95844792,943,4720,,6.00E-08,Q94521,Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),GO:0004059; GO:0004060; GO:0005737; GO:0048066; GO:0042420; GO:0030187; GO:0046334; GO:0045187; GO:0042429; GO:0030431,"aralkylamine N-acetyltransferase activity; arylamine N-acetyltransferase activity; cytoplasm; developmental pigmentation; dopamine catabolic process; melatonin biosynthetic process; octopamine catabolic process; regulation of circadian sleep/wake cycle, sleep; serotonin catabolic process; sleep",PF00583;,,,,,,,,,DNAT_DROME,Drosophila melanogaster (Fruit fly),"catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]" comp130238_c1_seq1,984,41.4634,0.85803559,21,279,,8.00E-07,A8MXQ7,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,,,,,,5.00E-18,ruditapes_c25681,,,,,YH010_HUMAN,Homo sapiens (Human), comp130242_c0_seq3,1674,47.5508,0.54039113,33,24,,3.00E-100,Q60974,Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) (Retinoid X receptor-interacting protein 13) (RIP13),Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) (Retinoid X receptor-interacting protein 13) (RIP13),GO:0002361; GO:0042632; GO:0003682; GO:0016568; GO:0032922; GO:0005829; GO:0060318; GO:0035033; GO:0014067; GO:0000122; GO:0031065; GO:0040014; GO:0046965; GO:0043565; GO:0003700; GO:0021794; GO:0046966; GO:0003714; GO:0005667; GO:0044212; GO:0006351; GO:0017053,"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; cholesterol homeostasis; chromatin binding; chromatin modification; circadian regulation of gene expression; cytosol; definitive erythrocyte differentiation; histone deacetylase regulator activity; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone deacetylation; regulation of multicellular organism growth; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; thalamus development; thyroid hormone receptor binding; transcription corepressor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent; transcriptional repressor complex",PF15784;PF00249;,3.00E-102,CHOYP_LOC588549.2.2,1.00E-27,ruditapes_c28679,,,,,NCOR1_MOUSE,Mus musculus (Mouse),"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cholesterol homeostasis [GO:0042632]; chromatin modification [GO:0016568]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; definitive erythrocyte differentiation [GO:0060318]; negative regulation of JNK cascade [GO:0046329]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072362]; regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter [GO:0072368]; regulation of multicellular organism growth [GO:0040014]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle assembly [GO:0051225]; thalamus development [GO:0021794]; transcription, DNA-templated [GO:0006351]" comp130243_c0_seq1,1955,39.6419,0.90087732,209,3527,,6.00E-107,P33477,Annexin A11 (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50),Annexin A11 (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50),GO:0044548; GO:0005509; GO:0005544; GO:0007109; GO:0042470; GO:0030496; GO:0005635; GO:0005654; GO:0005819,"S100 protein binding; calcium ion binding; calcium-dependent phospholipid binding; cytokinesis, completion of separation; melanosome; midbody; nuclear envelope; nucleoplasm; spindle",PF00191;,,,7.00E-26,ruditapes2_c1449,,,,,ANX11_RABIT,Oryctolagus cuniculus (Rabbit),cell cycle [GO:0007049]; cell division [GO:0051301] comp130243_c0_seq2,1955,39.6419,1.01864144,16,807,,5.00E-104,P20073,Annexin A7 (Annexin VII) (Annexin-7) (Synexin),Annexin A7 (Annexin VII) (Annexin-7) (Synexin),GO:0005509; GO:0005544; GO:0008283; GO:0006874; GO:0009992; GO:0005829; GO:0005789; GO:0007599; GO:0005635; GO:0005634; GO:0005886; GO:0008360; GO:0009651; GO:0035176; GO:0031982,calcium ion binding; calcium-dependent phospholipid binding; cell proliferation; cellular calcium ion homeostasis; cellular water homeostasis; cytosol; endoplasmic reticulum membrane; hemostasis; nuclear envelope; nucleus; plasma membrane; regulation of cell shape; response to salt stress; social behavior; vesicle,PF00191;,,,,,,,,,ANXA7_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; membrane fusion [GO:0061025]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to calcium ion [GO:0051592]; response to organic cyclic compound [GO:0014070]; response to salt stress [GO:0009651]; social behavior [GO:0035176] comp130245_c0_seq1,1314,34.8554,0.7788354,2082,14915,,2.00E-49,Q6GPQ6,Endothelial differentiation-related factor 1 homolog (EDF-1),Endothelial differentiation-related factor 1 homolog (EDF-1),GO:0005634; GO:0006355; GO:0043565; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF01381;PF08523;,6.00E-46,CHOYP_SI_CH211-197G15.10.6.7,2.00E-74,ruditapes2_c1561,,,,,EDF1_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130253_c1_seq2,1769,43.8101,0.31916183,51,42,,6.00E-10,Q5VZ19,Tudor domain-containing protein 10,Tudor domain-containing protein 10,GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;PF00567;,,,,,,,,,TDR10_HUMAN,Homo sapiens (Human), comp130253_c1_seq3,299,41.1371,0.41667133,3,0,,4.00E-06,P21187,Polyadenylate-binding protein (PABP) (Poly(A)-binding protein),Polyadenylate-binding protein (PABP) (Poly(A)-binding protein),GO:0071013; GO:0009953; GO:0005811; GO:0003730; GO:0000398; GO:0007140; GO:0007112; GO:0005875; GO:1901215; GO:0000166; GO:0048599; GO:0008143; GO:0045727; GO:0071011; GO:0045314; GO:0007289; GO:0007268,"catalytic step 2 spliceosome; dorsal/ventral pattern formation; lipid particle; mRNA 3'-UTR binding; mRNA splicing, via spliceosome; male meiosis; male meiosis cytokinesis; microtubule associated complex; negative regulation of neuron death; nucleotide binding; oocyte development; poly(A) RNA binding; positive regulation of translation; precatalytic spliceosome; regulation of compound eye photoreceptor development; spermatid nucleus differentiation; synaptic transmission",PF00658;PF00076;,,,,,,,,,PABP_DROME,Drosophila melanogaster (Fruit fly),"chemical synaptic transmission [GO:0007268]; dorsal/ventral pattern formation [GO:0009953]; male meiosis [GO:0007140]; male meiosis cytokinesis [GO:0007112]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of neuron death [GO:1901215]; neurogenesis [GO:0022008]; oocyte development [GO:0048599]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of compound eye photoreceptor development [GO:0045314]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]" comp130260_c0_seq1,1628,39.8034,0.51544536,920,3636,,0,A7RRJ0,Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1),Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1),GO:0003677; GO:0006281; GO:0006260; GO:0004519; GO:0004527; GO:0046872; GO:0005739; GO:0090305; GO:0005730; GO:0005654,DNA binding; DNA repair; DNA replication; endonuclease activity; exonuclease activity; metal ion binding; mitochondrion; nucleic acid phosphodiester bond hydrolysis; nucleolus; nucleoplasm,PF00867;PF00752;,0,CHOYP_FEN1.1.1,,,5.00E-96,CU991591.p.cg.6,8,,FEN1_NEMVE,Nematostella vectensis (Starlet sea anemone),"base-excision repair [GO:0006284]; DNA replication, removal of RNA primer [GO:0043137]" comp130261_c0_seq1,743,45.2221,1.24473766,417,3016,,1.00E-09,P74148,Universal stress protein Sll1388 (USP Sll1388),Universal stress protein Sll1388 (USP Sll1388),GO:0006950,response to stress,PF00582;,5.00E-12,CHOYP_NEMVEDRAFT_V1G242153.1.4,3.00E-25,ruditapes_c9630,,,,,Y1388_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),response to stress [GO:0006950] comp130266_c1_seq2,788,28.934,0.24512661,12,21,,,,,,,,,,,1.00E-11,ruditapes_c4529,,,,,,, comp130271_c0_seq1,1088,44.6691,1.00022196,12,0,,8.00E-25,Q8VII6,Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92),Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92),GO:0016021; GO:0006810,integral to membrane; transport,PF04515;,,,,,,,,,CTL1_RAT,Rattus norvegicus (Rat),transport [GO:0006810] comp130271_c0_seq2,879,45.0512,1.03297061,0,0,,2.00E-18,Q9VZE7,CTL-like protein 1,CTL-like protein 1,GO:0016021,integral to membrane,PF04515;,,,,,,,,,CTLH1_DROME,Drosophila melanogaster (Fruit fly), comp130271_c1_seq2,422,42.891,0.78742065,2,0,,5.00E-12,Q921V7,Choline transporter-like protein 3 (Solute carrier family 44 member 3),Choline transporter-like protein 3 (Solute carrier family 44 member 3),GO:0016021,integral to membrane,PF04515;,,,,,,,,,CTL3_MOUSE,Mus musculus (Mouse), comp130277_c0_seq19,1803,48.2529,0.64895883,0,0,,1.00E-20,P97393,Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),GO:0005525; GO:0005096; GO:0005737; GO:0016020; GO:0043547; GO:0030335; GO:0002053; GO:0008361; GO:0007264,GTP binding; GTPase activator activity; cytoplasm; membrane; positive regulation of GTPase activity; positive regulation of cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; small GTPase mediated signal transduction,PF01846;PF00071;PF00620;PF16512;,,,,,,,,,RHG05_MOUSE,Mus musculus (Mouse),positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264] comp130277_c0_seq9,1297,49.9614,0.68070905,0,0,,2.00E-21,P97393,Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B),GO:0005525; GO:0005096; GO:0005737; GO:0016020; GO:0043547; GO:0030335; GO:0002053; GO:0008361; GO:0007264,GTP binding; GTPase activator activity; cytoplasm; membrane; positive regulation of GTPase activity; positive regulation of cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; small GTPase mediated signal transduction,PF01846;PF00071;PF00620;PF16512;,,,,,,,,,RHG05_MOUSE,Mus musculus (Mouse),positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264] comp130280_c0_seq1,506,45.0593,0.89977203,1,28,,2.00E-12,A6WFC5,Inositol 2-dehydrogenase (EC 1.1.1.18) (Myo-inositol 2-dehydrogenase) (MI 2-dehydrogenase),Inositol 2-dehydrogenase (EC 1.1.1.18) (Myo-inositol 2-dehydrogenase) (MI 2-dehydrogenase),GO:0050112; GO:0019310,inositol 2-dehydrogenase activity; inositol catabolic process,PF01408;,,,,,,,,,IOLG_KINRD,Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216),inositol catabolic process [GO:0019310] comp130280_c0_seq3,708,43.9266,0.99991903,57,234,,3.00E-34,O05389,Uncharacterized oxidoreductase YrbE (EC 1.-.-.-),Uncharacterized oxidoreductase YrbE (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF01408;PF02894;,4.00E-13,CHOYP_NEMVEDRAFT_V1G188927.1.1,,,,,,,YRBE_BACSU,Bacillus subtilis (strain 168),oxidation-reduction process [GO:0055114] comp130297_c0_seq1,1746,41.4662,0.40201596,53,247,,6.00E-47,Q68CJ9,Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3],Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3],GO:0005737; GO:0005789; GO:0016021; GO:0005634; GO:0006986; GO:0043565; GO:0003700; GO:0006351,"cytoplasm; endoplasmic reticulum membrane; integral to membrane; nucleus; response to unfolded protein; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00170;,4.00E-30,CHOYP_LOC100371102.1.1,,,,,,,CR3L3_HUMAN,Homo sapiens (Human),endoplasmic reticulum unfolded protein response [GO:0030968]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440] comp130300_c1_seq3,467,38.9722,0.56624579,162,273,,,,,,,,,,,9.00E-11,ruditapes_c7836,,,,,,, comp130306_c1_seq1,462,42.8571,0.28448674,24,14,,4.00E-26,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,,,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp130307_c0_seq1,979,37.2829,0.76988236,17,699,,1.00E-07,Q7SIC1,Fucolectin,Fucolectin,GO:0005509; GO:0007155; GO:0005576; GO:0042806; GO:0010185; GO:0001868,"calcium ion binding; cell adhesion; extracellular region; fucose binding; regulation of cellular defense response; regulation of complement activation, lectin pathway",PF00754;,,,,,,,,,FUCL_ANGAN,Anguilla anguilla (European freshwater eel) (Muraena anguilla),"regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088]" comp130310_c0_seq2,879,40.9556,0.32374624,51,175,,,,,,,,,8.00E-11,CHOYP_SCHCODRAFT_114987.1.1,,,,,,,,, comp130316_c0_seq1,964,40.7676,0.64979869,36,183,,1.00E-70,P51522,Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1),Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZNF83_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130319_c1_seq2,2097,46.3042,0.57002654,0,0,,2.00E-14,O14523,C2 domain-containing protein 2-like (Transmembrane protein 24),C2 domain-containing protein 2-like (Transmembrane protein 24),GO:0016021,integral to membrane,,,,,,,,,,C2C2L_HUMAN,Homo sapiens (Human),positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] comp130319_c1_seq4,1983,46.4952,0.55117094,0,0,,7.00E-10,Q9Y426,C2 domain-containing protein 2,C2 domain-containing protein 2,GO:0005829; GO:0005576; GO:0005634,cytosol; extracellular region; nucleus,PF00168;,1.00E-19,CHOYP_LOC658718.2.2,,,,,,,CU025_HUMAN,Homo sapiens (Human), comp130319_c1_seq5,2640,44.9621,0.63806423,0,0,,3.00E-14,O14523,C2 domain-containing protein 2-like (Transmembrane protein 24),C2 domain-containing protein 2-like (Transmembrane protein 24),GO:0016021,integral to membrane,,1.00E-19,CHOYP_BRAFLDRAFT_118103.1.1,,,,,,,C2C2L_HUMAN,Homo sapiens (Human),positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] comp130319_c1_seq7,1213,45.9192,0.54952056,0,3,,,,,,,,,6.00E-20,CHOYP_LOC658718.2.2,,,,,,,,, comp130319_c1_seq9,2087,46.9574,0.59151141,0,0,,6.00E-10,Q9Y426,C2 domain-containing protein 2,C2 domain-containing protein 2,GO:0005829; GO:0005576; GO:0005634,cytosol; extracellular region; nucleus,PF00168;,1.00E-19,CHOYP_BRAFLDRAFT_118103.1.1,,,,,,,CU025_HUMAN,Homo sapiens (Human), comp130320_c0_seq2,1270,41.9685,0.31464997,0,0,,1.00E-138,Q9BZC7,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0043190; GO:0042626; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0006629; GO:0005765; GO:0005764; GO:0005815; GO:0032383; GO:0006357; GO:0042493; GO:0048545,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lipid metabolic process; lysosomal membrane; lysosome; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus",PF00005;,1.00E-54,CHOYP_TRIADDRAFT_10137.1.1,,,,,,,ABCA2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp130320_c0_seq3,1373,42.4618,0.29650426,0,0,,9.00E-141,P41234,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0016887; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0005765; GO:0005815; GO:0032383; GO:0006357; GO:0048545; GO:0006810,ATP binding; ATPase activity; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lysosomal membrane; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to steroid hormone stimulus; transport,PF00005;,2.00E-27,CHOYP_ABCA1.3.3,,,,,,,ABCA2_MOUSE,Mus musculus (Mouse),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545] comp130322_c0_seq1,393,41.7303,0.24042871,0,5,,8.00E-06,Q6PD05,Zinc finger protein 821,Zinc finger protein 821,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN821_MOUSE,Mus musculus (Mouse),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp130322_c0_seq2,1136,42.6056,0.56909898,0,10,,2.00E-56,Q5RDX1,Zinc finger protein 585A,Zinc finger protein 585A,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,Z585A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130322_c0_seq3,826,42.1308,0.71359457,0,0,,3.00E-33,Q5EBL2,Zinc finger protein 628,Zinc finger protein 628,GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN628_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130325_c0_seq1,1186,38.6172,0.50852973,140,511,,6.00E-27,Q9JKW1,Mitochondrial import inner membrane translocase subunit Tim22,Mitochondrial import inner membrane translocase subunit Tim22,GO:0016021; GO:0005743; GO:0015031,integral to membrane; mitochondrial inner membrane; protein transport,PF02466;,1.00E-16,CHOYP_TIM22.1.1,,,,,,,TIM22_RAT,Rattus norvegicus (Rat),protein import into mitochondrial inner membrane [GO:0045039] comp130327_c0_seq1,1194,48.995,0.52741168,0,0,,1.00E-18,Q14592,Zinc finger protein 460 (Zinc finger protein 272) (Zinc finger protein HZF8),Zinc finger protein 460 (Zinc finger protein 272) (Zinc finger protein HZF8),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN460_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130327_c0_seq2,1483,47.6062,0.54644565,0,0,,2.00E-26,Q9R0G7,Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b),Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b),GO:0070412; GO:0021846; GO:0005737; GO:0021766; GO:0046872; GO:0001755; GO:0001843; GO:0005730; GO:0043507; GO:0030177; GO:0043565; GO:0003700; GO:0001756; GO:0006351,"R-SMAD binding; cell proliferation in forebrain; cytoplasm; hippocampus development; metal ion binding; neural crest cell migration; neural tube closure; nucleolus; positive regulation of JUN kinase activity; positive regulation of Wnt receptor signaling pathway; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; somitogenesis; transcription, DNA-dependent",PF05605;,,,,,,,,,ZEB2_MOUSE,Mus musculus (Mouse),cell proliferation in forebrain [GO:0021846]; central nervous system development [GO:0007417]; collateral sprouting [GO:0048668]; corpus callosum morphogenesis [GO:0021540]; corticospinal tract morphogenesis [GO:0021957]; developmental pigmentation [GO:0048066]; embryonic morphogenesis [GO:0048598]; hippocampus development [GO:0021766]; mammillary axonal complex development [GO:0061373]; melanocyte migration [GO:0097324]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lens fiber cell differentiation [GO:1902748]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of melanosome organization [GO:1903056]; somitogenesis [GO:0001756] comp130327_c0_seq3,1668,47.8417,0.53033981,4,2,,1.00E-33,P28166,Zinc finger protein 1 (Zinc finger homeodomain protein 1),Zinc finger protein 1 (Zinc finger homeodomain protein 1),GO:0003705; GO:0000977; GO:0019730; GO:0061321; GO:0008406; GO:0007507; GO:0007516; GO:0048542; GO:0007498; GO:0046872; GO:0008045; GO:0000122; GO:0005634; GO:0007280; GO:0048103,RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding; antimicrobial humoral response; garland nephrocyte differentiation; gonad development; heart development; hemocyte development; lymph gland development; mesoderm development; metal ion binding; motor neuron axon guidance; negative regulation of transcription from RNA polymerase II promoter; nucleus; pole cell migration; somatic stem cell division,PF00046;PF13912;,4.00E-49,CHOYP_PHUM_PHUM017930.1.1,,,,,,,ZFH1_DROME,Drosophila melanogaster (Fruit fly),antimicrobial humoral response [GO:0019730]; central nervous system development [GO:0007417]; garland nephrocyte differentiation [GO:0061321]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; heart development [GO:0007507]; hemocyte development [GO:0007516]; lymph gland development [GO:0048542]; mesoderm development [GO:0007498]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; pole cell migration [GO:0007280]; somatic stem cell division [GO:0048103] comp130331_c2_seq1,927,46.4941,0.30020739,21,4,,3.00E-65,Q8VEB2,Protein salvador homolog 1 (45 kDa WW domain protein) (mWW45),Protein salvador homolog 1 (45 kDa WW domain protein) (mWW45),GO:0005737; GO:0001942; GO:0035329; GO:0060575; GO:0030216; GO:0060487; GO:0060044; GO:0050680; GO:0005634; GO:0043065; GO:2000036; GO:0060412,cytoplasm; hair follicle development; hippo signaling cascade; intestinal epithelial cell differentiation; keratinocyte differentiation; lung epithelial cell differentiation; negative regulation of cardiac muscle cell proliferation; negative regulation of epithelial cell proliferation; nucleus; positive regulation of apoptotic process; regulation of stem cell maintenance; ventricular septum morphogenesis,PF00397;,5.00E-32,CHOYP_SAV1.1.1,,,,,,,SAV1_MOUSE,Mus musculus (Mouse),hair follicle development [GO:0001942]; hippo signaling [GO:0035329]; intestinal epithelial cell differentiation [GO:0060575]; keratinocyte differentiation [GO:0030216]; lung epithelial cell differentiation [GO:0060487]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of epithelial cell proliferation [GO:0050680]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein stabilization [GO:0050821]; regulation of organ growth [GO:0046620]; regulation of stem cell population maintenance [GO:2000036]; ventricular septum morphogenesis [GO:0060412] comp130331_c2_seq2,698,43.8395,0.32960459,0,0,,,,,,,,,8.00E-35,CHOYP_BRAFLDRAFT_117824.1.1,,,,,,,,, comp130334_c1_seq1,1929,43.5977,0.49328666,68,283,,0,Q5ZLD7,Vacuolar protein sorting-associated protein 53 homolog,Vacuolar protein sorting-associated protein 53 homolog,GO:0005794; GO:0010008; GO:0015031,Golgi apparatus; endosome membrane; protein transport,PF04100;,2.00E-179,CHOYP_VPS53.1.1,,,2.00E-87,AM866620.p.cg.6,5,male gonad,VPS53_CHICK,Gallus gallus (Chicken),"endocytic recycling [GO:0032456]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp130335_c0_seq1,839,35.2801,0.34520597,634,2285,,2.00E-17,Q2YDI5,"39S ribosomal protein L48, mitochondrial (L48mt) (MRP-L48)","39S ribosomal protein L48, mitochondrial (L48mt) (MRP-L48)",GO:0005761,mitochondrial ribosome,PF00338;,,,,,,,,,RM48_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp130336_c0_seq11,227,36.1233,0.54546513,5,13,,3.00E-10,Q02026,Escargot/snail protein homolog (Fragment),Escargot/snail protein homolog (Fragment),GO:0003677; GO:0046872; GO:0005634,DNA binding; metal ion binding; nucleus,PF00096;,,,,,,,,,ESCA_PHOPA,Pholcus phalangioides (Daddy-long-legs spider) (Cellar spider), comp130336_c0_seq2,208,39.4231,0.50001156,3,0,,2.00E-10,Q3U381,Zinc finger protein 692,Zinc finger protein 692,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN692_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130336_c0_seq6,322,39.441,0.40114644,12,4,,9.00E-24,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp130336_c0_seq7,254,40.1575,0.49095871,5,2,,4.00E-25,Q14584,Zinc finger protein 266 (Zinc finger protein HZF1),Zinc finger protein 266 (Zinc finger protein HZF1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN266_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130336_c0_seq8,237,37.1308,1.10642466,0,25,,2.00E-23,Q8TC21,Zinc finger protein 596,Zinc finger protein 596,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN596_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130336_c0_seq9,311,37.6206,0.72940555,0,14,,2.00E-09,P31509,Escargot/snail protein homolog (Fragment),Escargot/snail protein homolog (Fragment),GO:0003677; GO:0046872; GO:0005634,DNA binding; metal ion binding; nucleus,PF00096;,,,,,,,,,ESCA_CRYAP,Cryptops anomalans (Centipede), comp130350_c0_seq2,1392,37.4282,0.43970982,48,261,,6.00E-19,Q9CZH3,Proteasome assembly chaperone 3 (PAC-3) (mPAC3),Proteasome assembly chaperone 3 (PAC-3) (mPAC3),,,PF10178;,,,,,,,,,PSMG3_MOUSE,Mus musculus (Mouse), comp130359_c0_seq2,1724,37.877,0.97281783,122,405,,4.00E-23,O14508,Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2),Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2),GO:0008269; GO:0060397; GO:0005070; GO:0007568; GO:0005829; GO:0005131; GO:0043066; GO:0009968; GO:0005148; GO:0016567; GO:0001558; GO:0032355,JAK pathway signal transduction adaptor activity; JAK-STAT cascade involved in growth hormone signaling pathway; SH3/SH2 adaptor activity; aging; cytosol; growth hormone receptor binding; negative regulation of apoptotic process; negative regulation of signal transduction; prolactin receptor binding; protein ubiquitination; regulation of cell growth; response to estradiol stimulus,PF00017;PF07525;,,,,,,,,,SOCS2_HUMAN,Homo sapiens (Human),cellular response to hormone stimulus [GO:0032870]; cytokine-mediated signaling pathway [GO:0019221]; growth hormone receptor signaling pathway [GO:0060396]; JAK-STAT cascade [GO:0007259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; protein ubiquitination [GO:0016567]; regulation of cell growth [GO:0001558]; regulation of signal transduction [GO:0009966]; response to estradiol [GO:0032355] comp130361_c0_seq1,897,44.5931,0.35643451,26,76,,5.00E-71,Q5R9B8,DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP),DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP),GO:0080008; GO:0005634; GO:0016567,Cul4-RING ubiquitin ligase complex; nucleus; protein ubiquitination,PF00400;,6.00E-50,CHOYP_DCAF6.2.2,,,,,,,DCAF6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein ubiquitination [GO:0016567] comp130363_c0_seq1,1058,40.0756,0.49521288,3,5,,9.00E-42,P28852,Thymidine kinase (EC 2.7.1.21),Thymidine kinase (EC 2.7.1.21),GO:0005524; GO:0006260; GO:0046872; GO:0004797,ATP binding; DNA replication; metal ion binding; thymidine kinase activity,PF00265;,,,,,,,,,KITH_AMEPV,Amsacta moorei entomopoxvirus (AmEPV),DNA biosynthetic process [GO:0071897] comp130363_c0_seq2,891,41.6386,0.49261776,0,0,,,,,,,,,1.00E-53,CHOYP_LOC100368622.1.1,,,,,,,,, comp130363_c0_seq4,856,42.2897,0.49726744,0,0,,1.00E-74,P04184,"Thymidine kinase, cytosolic (EC 2.7.1.21)","Thymidine kinase, cytosolic (EC 2.7.1.21)",GO:0005524; GO:0006260; GO:0005737; GO:0051289; GO:0004797; GO:0008270,ATP binding; DNA replication; cytoplasm; protein homotetramerization; thymidine kinase activity; zinc ion binding,PF00265;,4.00E-58,CHOYP_LOC100368622.1.1,,,,,,,KITH_MOUSE,Mus musculus (Mouse),digestive tract development [GO:0048565]; DNA biosynthetic process [GO:0071897]; DNA metabolic process [GO:0006259]; fetal process involved in parturition [GO:0060138]; liver development [GO:0001889]; protein homotetramerization [GO:0051289]; response to copper ion [GO:0046688]; response to cortisol [GO:0051414]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636]; skeletal muscle cell proliferation [GO:0014856]; thymidine metabolic process [GO:0046104] comp130364_c0_seq2,1875,41.9733,0.51351718,390,1963,,3.00E-140,Q15061,WD repeat-containing protein 43,WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog),GO:0005730,nucleolus,PF04003;PF00400;,,,,,,,,,WDR43_HUMAN,Homo sapiens (Human),establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; reproduction [GO:0000003]; rRNA processing [GO:0006364]; vesicle transport along microtubule [GO:0047496] comp130370_c0_seq1,1792,36.7746,0.62345896,217,82,,,,,,,,,6.00E-22,CHOYP_contig_005882,,,,,,,,, comp130371_c1_seq1,1054,43.4535,0.7871334,10361,72210,,0,Q25008,Tubulin alpha-1 chain (Alpha-I tubulin),Tubulin alpha-1 chain (Alpha-I tubulin),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC100366892.1.3,0,ruditapes_c12803,,,,,TBA1_HOMAM,Homarus americanus (American lobster),microtubule-based process [GO:0007017] comp130371_c2_seq1,428,48.1308,1.01246659,1606,13475,,5.00E-35,P33628,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0005200,GTP binding; cytoplasm; microtubule; microtubule-based process; structural constituent of cytoskeleton,PF00091;,1.00E-73,CHOYP_TBB.5.7,2.00E-62,ruditapes_c25365,,,,,TBA_PICAB,Picea abies (Norway spruce) (Picea excelsa),microtubule-based process [GO:0007017] comp130372_c0_seq1,1282,40.0156,0.64364588,1419,5572,,3.00E-60,O35130,Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine-N1-)-methyltransferase NEP1) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1),Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1),GO:0005730; GO:0070037; GO:0019843,nucleolus; rRNA (pseudouridine) methyltransferase activity; rRNA binding,PF03587;,3.00E-74,CHOYP_NEMVEDRAFT_V1G166546.1.1,2.00E-137,ruditapes_c10828,,,,,NEP1_MOUSE,Mus musculus (Mouse),"blastocyst development [GO:0001824]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; nucleologenesis [GO:0017126]; rRNA base methylation [GO:0070475]" comp130373_c1_seq2,716,46.3687,0.69221478,28,7,,4.00E-41,Q6NRS1,Inhibitor of Bruton tyrosine kinase (IBtk),Inhibitor of Bruton tyrosine kinase (IBtk),GO:0005737; GO:0016020,cytoplasm; membrane,PF12796;PF00651;PF00415;,2.00E-11,CHOYP_IBTK.1.1,,,,,,,IBTK_XENLA,Xenopus laevis (African clawed frog), comp130375_c0_seq1,833,46.6987,0.52663155,0,0,,1.00E-18,Q80U44,Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal-associated FYVE domain protein),Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal-associated FYVE domain protein),GO:0005545; GO:0031901; GO:0016197; GO:0046872; GO:0005547; GO:0006622; GO:0008565,"1-phosphatidylinositol binding; early endosome membrane; endosomal transport; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; protein targeting to lysosome; protein transporter activity",PF11979;PF01363;,,,,,,,,,ZFY16_MOUSE,Mus musculus (Mouse),endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622] comp130375_c0_seq2,1236,45.712,0.60613837,31,8,,2.00E-91,Q6ZV73,"FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)","FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)",GO:0005794; GO:0005089; GO:0030036; GO:0005856; GO:0046847; GO:0005085; GO:0030027; GO:0046872; GO:0005543; GO:0043088; GO:0008360; GO:0001726; GO:0031267,Golgi apparatus; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cytoskeleton; filopodium assembly; guanyl-nucleotide exchange factor activity; lamellipodium; metal ion binding; phospholipid binding; regulation of Cdc42 GTPase activity; regulation of cell shape; ruffle; small GTPase binding,PF01363;PF00169;PF00621;,1.00E-28,CHOYP_FGD6.1.1,,,,,,,FGD6_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023] comp130378_c2_seq1,1100,38.9091,0.40942832,850,7596,,9.00E-86,Q6P7Q4,Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase),Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase),GO:0005975; GO:0006749; GO:0004462; GO:0046872; GO:0009438; GO:0043066; GO:0006357,carbohydrate metabolic process; glutathione metabolic process; lactoylglutathione lyase activity; metal ion binding; methylglyoxal metabolic process; negative regulation of apoptotic process; regulation of transcription from RNA polymerase II promoter,PF00903;,6.00E-64,CHOYP_GLO1.1.1,,,,,,,LGUL_RAT,Rattus norvegicus (Rat),carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp130388_c1_seq1,995,37.4874,0.43478305,58,226,,2.00E-39,Q5BU09,E2F-associated phosphoprotein (EAPP),E2F-associated phosphoprotein (EAPP),GO:0005794; GO:0034244; GO:0005634; GO:0008284; GO:0032968,Golgi apparatus; negative regulation of transcription elongation from RNA polymerase II promoter; nucleus; positive regulation of cell proliferation; positive regulation of transcription elongation from RNA polymerase II promoter,PF10238;,,,,,,,,,EAPP_MOUSE,Mus musculus (Mouse),negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243] comp130396_c0_seq1,1365,43.663,0.55398371,57,196,,1.00E-108,O54826,Protein AF-10,Protein AF-10,GO:0005634; GO:0008270,nucleus; zinc ion binding,,1.00E-104,CHOYP_PHUM_PHUM498110.1.1,,,,,,,AF10_MOUSE,Mus musculus (Mouse),positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp130401_c0_seq2,1314,41.3242,1.08295476,7,346,,1.00E-33,O69669,Histidine-specific methyltransferase EgtD (EC 2.1.1.44) (Histidine-alpha-N-methyltransferase),,GO:0052707; GO:0030745; GO:0052704; GO:0005886; GO:0008276,"N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine; dimethylhistidine N-methyltransferase activity; ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine; plasma membrane; protein methyltransferase activity",,,,1.00E-46,ruditapes_c23704,,,,,EGTD_MYCTU,, comp130403_c0_seq3,2144,40.3451,0.39052217,0,0,,3.00E-11,Q54HW1,26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),,,PF12796;,5.00E-24,CHOYP_LOC100377359.1.1,,,,,,,PSD10_DICDI,Dictyostelium discoideum (Slime mold), comp130404_c0_seq1,395,32.4051,0.48387407,9,16,,,,,,,,,3.00E-55,CHOYP_LOC100743250.1.1,,,,,,,,, comp130404_c2_seq5,1545,39.7411,0.46287445,0,0,,,,,,,,,7.00E-52,CHOYP_LOC662279.1.1,,,,,,,,, comp130404_c2_seq6,1195,38.6611,0.69905964,0,11,,2.00E-41,Q14642,"Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)","Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)",GO:0007154; GO:0043647; GO:0052659; GO:0052658; GO:0004445; GO:0046856; GO:0005886,"cell communication; inositol phosphate metabolic process; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; inositol-1,4,5-trisphosphate 5-phosphatase activity; inositol-polyphosphate 5-phosphatase activity; phosphatidylinositol dephosphorylation; plasma membrane",PF03372;,4.00E-66,CHOYP_LOC100743250.1.1,,,,,,,I5P1_HUMAN,Homo sapiens (Human),inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol dephosphorylation [GO:0046856] comp130407_c0_seq1,612,32.1895,0.61670185,67,386,,4.00E-06,Q9P031,Thyroid transcription factor 1-associated protein 26 (TTF-1-associated protein 26) (Coiled-coil domain-containing protein 59) (TTF-1-associated protein BR2),Thyroid transcription factor 1-associated protein 26 (TTF-1-associated protein 26) (Coiled-coil domain-containing protein 59) (TTF-1-associated protein BR2),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08524;,,,3.00E-24,ruditapes_c25092,,,,,TAP26_HUMAN,Homo sapiens (Human),"cellular protein metabolic process [GO:0044267]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130408_c0_seq1,1234,39.4652,0.499916,660,54,,7.00E-65,Q3KQ80,O(6)-methylguanine-induced apoptosis 2 (MAPO2) (Sperm-tail PG-rich repeat-containing protein 1),O(6)-methylguanine-induced apoptosis 2 (MAPO2) (Sperm-tail PG-rich repeat-containing protein 1),GO:0006915; GO:0005737; GO:0005634,apoptotic process; cytoplasm; nucleus,PF07004;,3.00E-113,CHOYP_LOC100178916.1.1,,,,,,,STPG1_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915] comp130412_c0_seq2,1350,33.1852,0.35828253,0,24,,3.00E-23,P53803,"DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)","DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)",GO:0006370; GO:0003677; GO:0005736; GO:0005665; GO:0005666; GO:0003899; GO:0005829; GO:0045087; GO:0000398; GO:0032481; GO:0050434; GO:0006356; GO:0006363; GO:0006386; GO:0006362; GO:0006368; GO:0006385; GO:0006361; GO:0006367; GO:0006283; GO:0016032; GO:0008270,"7-methylguanosine mRNA capping; DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; cytosol; innate immune response; mRNA splicing, via spliceosome; positive regulation of type I interferon production; positive regulation of viral transcription; regulation of transcription from RNA polymerase I promoter; termination of RNA polymerase I transcription; termination of RNA polymerase III transcription; transcription elongation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; transcription elongation from RNA polymerase III promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; viral process; zinc ion binding",PF03604;,3.00E-30,CHOYP_POLR2K.1.1,1.00E-39,ruditapes_c22271,,,,,RPAB4_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of type I interferon production [GO:0032481]; positive regulation of viral transcription [GO:0050434]; regulation of transcription from RNA polymerase I promoter [GO:0006356]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; termination of RNA polymerase I transcription [GO:0006363]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp130414_c0_seq1,1395,33.2616,0.7306172,472,4526,,2.00E-73,Q6GLE1,Coiled-coil domain-containing protein 25,Coiled-coil domain-containing protein 25,,,PF05670;,8.00E-102,CHOYP_PHUM_PHUM278110.1.1,6.00E-126,ruditapes_c11533,,,,,CCD25_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp130415_c0_seq1,1054,37.9507,0.61157934,274,380,,1.00E-22,Q6AXZ2,Leucine-rich repeat-containing protein 46,Leucine-rich repeat-containing protein 46,,,,3.00E-16,CHOYP_BRAFLDRAFT_125776.1.2,,,,,,,LRC46_RAT,Rattus norvegicus (Rat), comp130416_c0_seq1,1681,38.0131,0.46618642,2510,33,,2.00E-09,Q96LY2,Coiled-coil domain-containing protein 74B,Coiled-coil domain-containing protein 74B,,,PF14917;,1.00E-88,CHOYP_LOC100377585.1.3,,,,,,,CC74B_HUMAN,Homo sapiens (Human), comp130417_c2_seq2,1867,39.2073,0.53385048,5,5,,1.00E-32,Q5VV67,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC),Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC),GO:0003723; GO:0000166; GO:0005634; GO:0006355; GO:0006351,"RNA binding; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00076;,1.00E-25,CHOYP_LOC100550090.1.1,,,,,,,PPRC1_HUMAN,Homo sapiens (Human),"mitochondrion organization [GO:0007005]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp130419_c0_seq1,278,43.5252,0.41175267,2,11,,1.00E-15,P31319,cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A),cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A),GO:0030552; GO:0005952; GO:0008603,cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity,PF00027;PF02197;,,,,,,,,,KAPR_APLCA,Aplysia californica (California sea hare), comp130419_c1_seq2,1793,40.7139,0.95850918,2,135,,0,Q13976,cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI),cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI),GO:0005524; GO:0005794; GO:0030036; GO:0007596; GO:0030553; GO:0004692; GO:0005246; GO:0005829; GO:0016358; GO:0030900; GO:0090331; GO:0001764; GO:0005886; GO:0043087; GO:0007165,ATP binding; Golgi apparatus; actin cytoskeleton organization; blood coagulation; cGMP binding; cGMP-dependent protein kinase activity; calcium channel regulator activity; cytosol; dendrite development; forebrain development; negative regulation of platelet aggregation; neuron migration; plasma membrane; regulation of GTPase activity; signal transduction,PF00027;PF16808;PF00069;,0,CHOYP_KGP1.1.1,,,,,,,KGP1_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of platelet aggregation [GO:0090331]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165] comp130419_c1_seq3,1266,39.8104,0.90419325,148,0,,5.00E-06,P13497,Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP),Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP),GO:0005794; GO:0005509; GO:0001502; GO:0030154; GO:0030198; GO:0005576; GO:0005615; GO:0042157; GO:0004222; GO:0001503; GO:0061036; GO:0005578; GO:0006508; GO:0044281; GO:0008270,Golgi apparatus; calcium ion binding; cartilage condensation; cell differentiation; extracellular matrix organization; extracellular region; extracellular space; lipoprotein metabolic process; metalloendopeptidase activity; ossification; positive regulation of cartilage development; proteinaceous extracellular matrix; proteolysis; small molecule metabolic process; zinc ion binding,PF01400;PF00431;PF07645;,,,,,,,,,BMP1_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; cartilage condensation [GO:0001502]; cell development [GO:0048468]; extracellular matrix disassembly [GO:0022617]; lipoprotein metabolic process [GO:0042157]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395] comp130419_c1_seq4,1248,40.5449,1.00934955,0,4,,9.00E-40,Q9Y2H1,Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2),Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2),GO:0005524; GO:0015629; GO:0005737; GO:0007243; GO:0000287; GO:0005634; GO:0005886; GO:0004674; GO:0051128,ATP binding; actin cytoskeleton; cytoplasm; intracellular protein kinase cascade; magnesium ion binding; nucleus; plasma membrane; protein serine/threonine kinase activity; regulation of cellular component organization,PF00069;PF00433;,,,,,,,,,ST38L_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of cellular component organization [GO:0051128] comp130421_c0_seq1,2052,43.2261,0.58497185,444,2400,,0,Q9Y113,Negative elongation factor B,Negative elongation factor B,GO:0032021; GO:0003723; GO:0005694; GO:0034244; GO:0007070; GO:0045944; GO:0006351; GO:0017053,"NELF complex; RNA binding; chromosome; negative regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter during mitosis; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; transcriptional repressor complex",PF06209;,2.00E-142,CHOYP_NELFB.1.2,8.00E-32,ruditapes_c13509,,,,,NELFB_DROME,Drosophila melanogaster (Fruit fly),"negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp130422_c1_seq1,1698,41.4605,0.40018695,109,108,,2.00E-177,Q5RBH9,Nuclear receptor-binding protein,Nuclear receptor-binding protein,GO:0006888; GO:0005938; GO:0012505; GO:0030027; GO:0016020; GO:0048471; GO:0006468; GO:0016772,"ER to Golgi vesicle-mediated transport; cell cortex; endomembrane system; lamellipodium; membrane; perinuclear region of cytoplasm; protein phosphorylation; transferase activity, transferring phosphorus-containing groups",PF07714;,5.00E-169,CHOYP_LOC100123075.1.1,,,,,,,NRBP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ER to Golgi vesicle-mediated transport [GO:0006888]; protein phosphorylation [GO:0006468] comp130423_c0_seq1,1259,43.5266,0.9917957,3,153,,7.00E-136,Q92038,Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase),Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase),GO:0005789; GO:0006633; GO:0016021; GO:0005506; GO:0006950; GO:0004768,endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; iron ion binding; response to stress; stearoyl-CoA 9-desaturase activity,PF00487;,,,1.00E-32,ruditapes_c3897,,,,,ACOD_CYPCA,Cyprinus carpio (Common carp),unsaturated fatty acid biosynthetic process [GO:0006636] comp130423_c0_seq2,648,45.9877,0.82152094,2,0,,,,,,,,,2.00E-41,CHOYP_LOC100564278.1.1,,,,,,,,, comp130424_c0_seq1,1311,38.5965,0.41058404,4,4,,1.00E-55,Q8N5I4,Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY),Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY) (Short chain dehydrogenase/reductase family 46C member 1) (Short chain dehydrogenase/reductase family 7C member 6),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,DHRSX_HUMAN,Homo sapiens (Human), comp130424_c0_seq2,1376,38.3721,0.39571261,14,5,,6.00E-47,Q6RVV4,"Short-chain dehydrogenase TIC 32, chloroplastic (EC 1.1.1.-) (Translocon at the inner envelope membrane of chloroplasts 32) (PsTIC32)","Short-chain dehydrogenase TIC 32, chloroplastic (EC 1.1.1.-) (Translocon at the inner envelope membrane of chloroplasts 32) (PsTIC32)",GO:0009706; GO:0016491; GO:0015031,chloroplast inner membrane; oxidoreductase activity; protein transport,PF00106;,,,,,,,,,TIC32_PEA,Pisum sativum (Garden pea),protein transport [GO:0015031] comp130428_c1_seq2,1592,44.8492,0.50732504,20,24,,0,Q6NS52,Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta),Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta),GO:0005524; GO:0003951; GO:0005509; GO:0005737; GO:0004143; GO:0035556; GO:0005886; GO:0007205,ATP binding; NAD+ kinase activity; calcium ion binding; cytoplasm; diacylglycerol kinase activity; intracellular signal transduction; plasma membrane; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF14513;PF00609;PF00781;PF13499;,0,CHOYP_LOC100116104.1.1,,,,,,,DGKB_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205] comp130428_c1_seq4,1133,45.278,0.46931367,2,0,,1.00E-163,Q01583,Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),GO:0005524; GO:0003951; GO:0005509; GO:0004143; GO:0035556; GO:0007205,ATP binding; NAD+ kinase activity; calcium ion binding; diacylglycerol kinase activity; intracellular signal transduction; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF14513;PF00609;PF00781;,,,,,,,,,DGK1_DROME,Drosophila melanogaster (Fruit fly),intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313] comp130428_c1_seq5,472,45.9746,0.62500281,2,0,,2.00E-13,Q75K28,Calcium-binding protein NCSA (Neuronal calcium sensor 1 homolog),Calcium-binding protein NCSA (Neuronal calcium sensor 1 homolog),GO:0005509; GO:0030587,calcium ion binding; sorocarp development,PF13499;PF13833;,,,,,,,,,NCSA_DICDI,Dictyostelium discoideum (Slime mold),sorocarp development [GO:0030587] comp130433_c1_seq2,1004,39.3426,0.48017248,36,122,,4.00E-80,Q5REV5,"Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Protein SA homolog)","Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Protein SA homolog)",GO:0005524; GO:0047760; GO:0006633; GO:0015645; GO:0046872; GO:0005759,ATP binding; butyrate-CoA ligase activity; fatty acid biosynthetic process; fatty acid ligase activity; metal ion binding; mitochondrial matrix,PF00501;PF13193;,1.00E-58,CHOYP_ACSM3.1.1,5.00E-62,ruditapes_c11231,,,,,ACSM3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),fatty acid biosynthetic process [GO:0006633] comp130436_c0_seq2,1213,36.1913,0.44503416,0,0,,4.00E-20,Q6DKK2,"Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19)","Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19)",GO:0005813; GO:0000910; GO:0030496; GO:0005743; GO:0034551,centrosome; cytokinesis; midbody; mitochondrial inner membrane; mitochondrial respiratory chain complex III assembly,PF13374;,,,,,,,,,TTC19_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; mitochondrial respiratory chain complex III assembly [GO:0034551] comp130437_c0_seq1,1125,42.4,0.51533221,0,0,,8.00E-07,P35590,Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1),Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1),GO:0005524; GO:0001525; GO:0001701; GO:0005887; GO:0007498; GO:0016525; GO:0030336; GO:0045026; GO:0032526; GO:0004714,ATP binding; angiogenesis; in utero embryonic development; integral to plasma membrane; mesoderm development; negative regulation of angiogenesis; negative regulation of cell migration; plasma membrane fusion; response to retinoic acid; transmembrane receptor protein tyrosine kinase activity,PF00041;PF12661;PF00047;PF07714;,,,,,,,,,TIE1_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; in utero embryonic development [GO:0001701]; mesoderm development [GO:0007498]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration [GO:0030336]; plasma membrane fusion [GO:0045026]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] comp130437_c0_seq2,1954,42.6817,0.51934641,0,0,,2.00E-30,P98157,Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),GO:0005509; GO:0005905; GO:0006897; GO:0016021,calcium ion binding; coated pit; endocytosis; integral to membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp130437_c0_seq3,1257,42.2434,0.48395676,0,0,,2.00E-12,Q9W6F8,Wnt inhibitory factor 1 (WIF-1),Wnt inhibitory factor 1 (WIF-1),GO:0016055; GO:0005576; GO:0007275,Wnt receptor signaling pathway; extracellular region; multicellular organismal development,PF07974;PF12661;PF02019;,,,,,,,,,WIF1_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp130437_c0_seq4,1822,42.8101,0.54050064,0,0,,3.00E-31,P98157,Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),GO:0005509; GO:0005905; GO:0006897; GO:0016021,calcium ion binding; coated pit; endocytosis; integral to membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp130441_c1_seq1,790,43.5443,0.72487643,3,5,,7.00E-50,P0C6S7,Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1),Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1),GO:0015030; GO:0030054; GO:0005737; GO:0043197; GO:0014069; GO:0045211,Cajal body; cell junction; cytoplasm; dendritic spine; postsynaptic density; postsynaptic membrane,PF12796;PF00640;PF00536;,4.00E-64,CHOYP_ANS1B.1.1,,,,,,,ANS1B_RAT,Rattus norvegicus (Rat),receptor localization to synapse [GO:0097120] comp130441_c1_seq2,766,43.6031,0.69002241,2,14,,1.00E-52,Q92625,Ankyrin repeat and SAM domain-containing protein 1A (Odin),Ankyrin repeat and SAM domain-containing protein 1A (Odin),GO:0005737; GO:0048013; GO:0043005; GO:0016322; GO:0005634; GO:0006929,cytoplasm; ephrin receptor signaling pathway; neuron projection; neuron remodeling; nucleus; substrate-dependent cell migration,PF12796;PF00640;PF00536;PF07647;,,,,,,,,,ANS1A_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; neuron remodeling [GO:0016322]; substrate-dependent cell migration [GO:0006929] comp130441_c2_seq2,458,44.5415,0.75181012,0,0,,5.00E-08,Q3V1H9,Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5),Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5),,,PF00536;,3.00E-12,CHOYP_LOC663468.1.1,,,,,,,SAMD5_MOUSE,Mus musculus (Mouse), comp130442_c0_seq2,841,43.6385,1.30309708,61,0,,7.00E-43,Q1JP75,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0005903; GO:0005881; GO:0006006; GO:0016020; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; brush border; cytoplasmic microtubule; glucose metabolic process; membrane; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,,,,,,,DCXR_BOVIN,Bos taurus (Bovine),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp130442_c0_seq3,437,48.0549,1.19357515,0,0,,6.00E-31,Q91XV4,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (Sperm antigen P26h),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (Sperm antigen P26h),GO:0042732; GO:0050038; GO:0001669; GO:0005881; GO:0006006; GO:0016020; GO:0051289; GO:0005997,D-xylose metabolic process; L-xylulose reductase (NADP+) activity; acrosomal vesicle; cytoplasmic microtubule; glucose metabolic process; membrane; protein homotetramerization; xylulose metabolic process,,,,,,,,,,DCXR_MESAU,Mesocricetus auratus (Golden hamster),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp130462_c0_seq1,1484,34.973,0.44681832,84,283,,3.00E-36,Q400C7,Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2),Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2),GO:0008237; GO:0006508; GO:0008270,metallopeptidase activity; proteolysis; zinc ion binding,PF07998;,4.00E-17,CHOYP_LOC100372508.1.1,,,,,,,AMZ2_RAT,Rattus norvegicus (Rat), comp130463_c0_seq1,1923,42.4857,0.37041371,567,3723,,0,Q5XGB9,Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase),Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase),GO:0004177; GO:0005737; GO:0030145; GO:0008235; GO:0006508,aminopeptidase activity; cytoplasm; manganese ion binding; metalloexopeptidase activity; proteolysis,PF00883;PF02789;,5.00E-99,CHOYP_AMPL.1.1,8.00E-44,ruditapes_c10878,,,,,AMPL_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp130465_c0_seq1,1175,47.0638,0.28006689,4,33,,8.00E-42,Q8IN94,Trithorax group protein osa (Protein eyelid),Trithorax group protein osa (Protein eyelid),GO:0003677; GO:0016055; GO:0035060; GO:0016568; GO:0007480; GO:0008587; GO:0008586; GO:0046530; GO:0045893; GO:0042058; GO:0007379; GO:0006351; GO:0048190,"DNA binding; Wnt receptor signaling pathway; brahma complex; chromatin modification; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; photoreceptor cell differentiation; positive regulation of transcription, DNA-dependent; regulation of epidermal growth factor receptor signaling pathway; segment specification; transcription, DNA-dependent; wing disc dorsal/ventral pattern formation",PF01388;PF12031;,2.00E-39,CHOYP_OSA.1.2,,,,,,,OSA_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]" comp130465_c0_seq2,1978,47.9778,0.35170039,6,17,,3.00E-28,A2BH40,"AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)","AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)",GO:0043044; GO:0003677; GO:0016514; GO:0030521; GO:0003205; GO:0030900; GO:0042921; GO:0030520; GO:0071565; GO:0000122; GO:0001843; GO:0071564; GO:0000790; GO:0006337; GO:0003408; GO:0060674; GO:0045893; GO:0006351,"ATP-dependent chromatin remodeling; DNA binding; SWI/SNF complex; androgen receptor signaling pathway; cardiac chamber development; forebrain development; glucocorticoid receptor signaling pathway; intracellular estrogen receptor signaling pathway; nBAF complex; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; npBAF complex; nuclear chromatin; nucleosome disassembly; optic cup formation involved in camera-type eye development; placenta blood vessel development; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF12031;,3.00E-46,CHOYP_LOC100883763.1.1,,,,,,,ARI1A_MOUSE,Mus musculus (Mouse),"androgen receptor signaling pathway [GO:0030521]; ATP-dependent chromatin remodeling [GO:0043044]; cardiac chamber development [GO:0003205]; cardiac muscle cell differentiation [GO:0055007]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; forebrain development [GO:0030900]; glucocorticoid receptor signaling pathway [GO:0042921]; intracellular estrogen receptor signaling pathway [GO:0030520]; maintenance of chromatin silencing [GO:0006344]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; nucleosome disassembly [GO:0006337]; optic cup formation involved in camera-type eye development [GO:0003408]; placenta blood vessel development [GO:0060674]; positive regulation of transcription, DNA-templated [GO:0045893]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]" comp130465_c0_seq5,996,45.6827,0.45476406,3,7,,,,,,,,,,,2.00E-22,ruditapes_c14551,,,,,,, comp130472_c0_seq1,1082,42.8835,0.480373,3,11,,4.00E-18,Q94EI3,Peroxisome biogenesis protein 19-2 (Peroxin-19-2) (AtPEX19-2) (Peroxisomal membrane protein import receptor PEX19-2),Peroxisome biogenesis protein 19-2 (Peroxin-19-2) (AtPEX19-2) (Peroxisomal membrane protein import receptor PEX19-2),GO:0005829; GO:0005778; GO:0007031; GO:0015031,cytosol; peroxisomal membrane; peroxisome organization; protein transport,PF04614;,,,,,,,,,PE192_ARATH,Arabidopsis thaliana (Mouse-ear cress),peroxisome organization [GO:0007031]; protein targeting to peroxisome [GO:0006625] comp130472_c0_seq2,747,46.0509,0.52473879,0,0,,,,,,,,,5.00E-19,CHOYP_PEX2.2.2,,,,,,,,, comp130472_c0_seq3,1098,42.714,0.49603636,2,2,,3.00E-47,Q9QYU1,Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein),Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein),GO:0031526; GO:0005778; GO:0005777; GO:0007031,brush border membrane; peroxisomal membrane; peroxisome; peroxisome organization,PF04614;,,,,,,,,,PEX19_RAT,Rattus norvegicus (Rat),peroxisome organization [GO:0007031] comp130474_c0_seq1,1108,38.8989,0.23895732,179,0,,2.00E-14,P17221,Sex-determining protein fem-1 (Feminization of XX and XO animals protein 1),Sex-determining protein fem-1 (Feminization of XX and XO animals protein 1),GO:0005737; GO:0019100; GO:0019102; GO:0042006; GO:0016567,cytoplasm; male germ-line sex determination; male somatic sex determination; masculinization of hermaphroditic germ-line; protein ubiquitination,PF12796;,2.00E-20,CHOYP_BRAFLDRAFT_100807.1.1,,,,,,,FEM1_CAEEL,Caenorhabditis elegans,male germ-line sex determination [GO:0019100]; male somatic sex determination [GO:0019102]; masculinization of hermaphroditic germ-line [GO:0042006]; protein ubiquitination [GO:0016567]; transcription factor catabolic process [GO:0036369] comp130482_c0_seq3,1313,32.9779,0.39322839,121,156,,8.00E-06,Q6UW02,Cytochrome P450 20A1 (EC 1.14.-.-),Cytochrome P450 20A1 (EC 1.14.-.-),GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705,"heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP20A_HUMAN,Homo sapiens (Human), comp130484_c0_seq2,564,39.7163,0.61372185,18,53,,1.00E-72,O76031,"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial","ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial",GO:0005524; GO:0016887; GO:0046872; GO:0009841; GO:0005743; GO:0042645; GO:0005634; GO:0016504; GO:0006457; GO:0051603,ATP binding; ATPase activity; metal ion binding; mitochondrial endopeptidase Clp complex; mitochondrial inner membrane; mitochondrial nucleoid; nucleus; peptidase activator activity; protein folding; proteolysis involved in cellular protein catabolic process,PF07724;PF10431;,,,,,,,,,CLPX_HUMAN,Homo sapiens (Human),protein folding [GO:0006457]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp130485_c0_seq2,1216,43.9967,0.49848904,8,29,,3.00E-38,Q8WV16,DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A),DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A),GO:0080008; GO:0016567,Cul4-RING ubiquitin ligase complex; protein ubiquitination,,,,3.00E-46,ruditapes_c25511,,,,,DCAF4_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp130486_c0_seq1,1371,45.2225,1.04535026,50,64,,9.00E-33,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp130487_c1_seq1,398,56.2814,0.52747586,36,0,,7.00E-08,Q17RW2,Collagen alpha-1(XXIV) chain,Collagen alpha-1(XXIV) chain,GO:0005581; GO:0005788; GO:0030198; GO:0005201; GO:0005576,collagen; endoplasmic reticulum lumen; extracellular matrix organization; extracellular matrix structural constituent; extracellular region,PF01410;PF01391;,,,,,,,,,COOA1_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244] comp130488_c0_seq2,1204,43.4385,0.32709035,53,181,,3.00E-132,Q6GQ29,Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase),Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase),GO:0005794; GO:0004180; GO:0005783; GO:0005615; GO:0005764; GO:0046872; GO:0070573; GO:0043171; GO:0042803; GO:0006508,Golgi apparatus; carboxypeptidase activity; endoplasmic reticulum; extracellular space; lysosome; metal ion binding; metallodipeptidase activity; peptide catabolic process; protein homodimerization activity; proteolysis,PF04389;,8.00E-57,CHOYP_CBPQ.1.1,4.00E-20,ruditapes_lrc13943,,,,,CBPQ_XENLA,Xenopus laevis (African clawed frog),peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp130489_c0_seq2,1475,45.7627,0.73873908,24,257,,1.00E-48,P20241,Neuroglian,Neuroglian,GO:0008366; GO:0048675; GO:0005509; GO:0061343; GO:0048036; GO:0048813; GO:0007173; GO:0060857; GO:0008050; GO:0030175; GO:0007560; GO:0016021; GO:0016328; GO:0008049; GO:0035011; GO:0016319; GO:0021682; GO:0007158; GO:0005919; GO:0045924; GO:0035151; GO:0019991; GO:0050808; GO:0005923,"axon ensheathment; axon extension; calcium ion binding; cell adhesion involved in heart morphogenesis; central complex development; dendrite morphogenesis; epidermal growth factor receptor signaling pathway; establishment of glial blood-brain barrier; female courtship behavior; filopodium; imaginal disc morphogenesis; integral to membrane; lateral plasma membrane; male courtship behavior; melanotic encapsulation of foreign target; mushroom body development; nerve maturation; neuron cell-cell adhesion; pleated septate junction; regulation of female receptivity; regulation of tube size, open tracheal system; septate junction assembly; synapse organization; tight junction",PF13882;PF00041;PF07679;PF00047;,2.00E-13,CHOYP_DPSE_GA14061.1.1,,,,,,,NRG_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" comp13048_c0_seq1,321,41.7445,0.73718664,4,0,,3.00E-66,P30683,Guanine nucleotide-binding protein G(o) subunit alpha,Guanine nucleotide-binding protein G(o) subunit alpha,GO:0005525; GO:0003924; GO:0007188; GO:0046872; GO:0004871,GTP binding; GTPase activity; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; metal ion binding; signal transducer activity,PF00503;,2.00E-69,CHOYP_GNAO.1.1,,,,,,,GNAO_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188] comp13048_c0_seq2,277,40.4332,0.7433252,1,0,,1.00E-22,P50149,Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain),Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain),GO:0031683; GO:0001664; GO:0007199; GO:0005525; GO:0003924; GO:0007188; GO:0001580; GO:0050908; GO:0005834; GO:0046872; GO:0001917; GO:0001750; GO:0046549; GO:0016056; GO:0004871,G-protein beta/gamma-subunit complex binding; G-protein coupled receptor binding; G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; GTP binding; GTPase activity; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; detection of chemical stimulus involved in sensory perception of bitter taste; detection of light stimulus involved in visual perception; heterotrimeric G-protein complex; metal ion binding; photoreceptor inner segment; photoreceptor outer segment; retinal cone cell development; rhodopsin mediated signaling pathway; signal transducer activity,PF00503;,1.00E-14,CHOYP_GNAI.1.1,,,,,,,GNAT2_MOUSE,Mus musculus (Mouse),"adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of light stimulus involved in visual perception [GO:0050908]; G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199]; phototransduction [GO:0007602]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; response to light intensity [GO:0009642]; retinal cone cell development [GO:0046549]; visual perception [GO:0007601]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]" comp130490_c1_seq4,520,45.1923,0.79317388,0,3,,,,,,,,,5.00E-23,CHOYP_FLVC2.1.1,,,,,,,,, comp130490_c1_seq5,908,42.2907,0.66758323,9,319,,5.00E-84,Q91X85,Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT),Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT),GO:0020037; GO:0015232; GO:0016021; GO:0005886; GO:0055085,heme binding; heme transporter activity; integral to membrane; plasma membrane; transmembrane transport,PF07690;,9.00E-42,CHOYP_FLVCR2B.1.1,,,,,,,FLVC2_MOUSE,Mus musculus (Mouse),transmembrane transport [GO:0055085] comp130492_c0_seq1,307,42.3453,0.93122681,7,32,,,,,,,,,6.00E-19,CHOYP_LOC101156914.1.1,,,,,,,,, comp130492_c1_seq2,958,44.1545,1.04215142,6,24,,3.00E-08,P25942,Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40),Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40),GO:0042100; GO:0035631; GO:0006874; GO:0071260; GO:0051607; GO:0009897; GO:0005576; GO:0002768; GO:0006954; GO:0043231; GO:0030168; GO:0030890; GO:0043089; GO:0043123; GO:0043406; GO:0051092; GO:0032855; GO:2000353; GO:0032735; GO:0048304; GO:0090037; GO:0045944; GO:0042511; GO:0006461; GO:0004872; GO:0050776; GO:0051023; GO:0004871,B cell proliferation; CD40 receptor complex; cellular calcium ion homeostasis; cellular response to mechanical stimulus; defense response to virus; external side of plasma membrane; extracellular region; immune response-regulating cell surface receptor signaling pathway; inflammatory response; intracellular membrane-bounded organelle; platelet activation; positive regulation of B cell proliferation; positive regulation of Cdc42 GTPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAP kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of Rac GTPase activity; positive regulation of endothelial cell apoptotic process; positive regulation of interleukin-12 production; positive regulation of isotype switching to IgG isotypes; positive regulation of protein kinase C signaling cascade; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tyrosine phosphorylation of Stat1 protein; protein complex assembly; receptor activity; regulation of immune response; regulation of immunoglobulin secretion; signal transducer activity,PF00020;,,,,,,,,,TNR5_HUMAN,Homo sapiens (Human),apoptotic signaling pathway [GO:0097190]; B cell proliferation [GO:0042100]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response [GO:0006955]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tyrosine phosphorylation of Stat1 protein [GO:0042511]; protein complex assembly [GO:0006461]; protein kinase B signaling [GO:0043491]; regulation of cell proliferation [GO:0042127]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to lipopolysaccharide [GO:0032496]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp130497_c0_seq1,883,45.4134,0.78440421,57,28,,7.00E-40,A2AF47,Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2),Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2),GO:0005089; GO:0005543; GO:0007264,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;PF00169;,6.00E-25,CHOYP_DOCK9.2.2,,,,,,,DOC11_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp130498_c0_seq1,1501,40.04,0.44925244,82,366,,2.00E-53,Q5ZJQ8,Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1),Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1),GO:0016021,integral to membrane,PF00627;,7.00E-14,CHOYP_ISCW_ISCW023764.1.1,,,,,,,UBAC2_CHICK,Gallus gallus (Chicken),"negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein localization to endoplasmic reticulum [GO:0070972]" comp130500_c0_seq1,1198,47.3289,0.61232947,80,34,,6.00E-67,Q5T5Y3,Calmodulin-regulated spectrin-associated protein 1,Calmodulin-regulated spectrin-associated protein 1,GO:0005737; GO:0007010; GO:0005874; GO:0022604,cytoplasm; cytoskeleton organization; microtubule; regulation of cell morphogenesis,PF17095;PF11971;PF08683;,2.00E-25,CHOYP_LOC100943158.1.1,,,,,,,CAMP1_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604] comp130501_c0_seq1,537,45.9963,0.68393118,10,27,,8.00E-18,P97798,Neogenin,Neogenin,GO:0045296; GO:0007155; GO:0016021; GO:0007520; GO:0005886; GO:0004872; GO:0006355,"cadherin binding; cell adhesion; integral to membrane; myoblast fusion; plasma membrane; receptor activity; regulation of transcription, DNA-dependent",PF00041;PF07679;PF13895;PF06583;,,,,,,,,,NEO1_MOUSE,Mus musculus (Mouse),"axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; myoblast fusion [GO:0007520]; negative regulation of protein secretion [GO:0050709]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of transcription, DNA-templated [GO:0006355]" comp130501_c1_seq2,1252,50.0799,0.51309383,0,0,,4.00E-09,Q7Z5N4,Protein sidekick-1,Protein sidekick-1,GO:0007155; GO:0016021,cell adhesion; integral to membrane,PF00041;PF07679;,,,,,,,,,SDK1_HUMAN,Homo sapiens (Human),behavioral response to cocaine [GO:0048148]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of dendritic spine development [GO:0060998]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] comp130501_c1_seq4,561,48.8414,0.53923412,0,0,,5.00E-12,Q9VWE0,Cytokine receptor (Protein domeless),Cytokine receptor (Protein domeless),GO:0007259; GO:0016324; GO:0016327; GO:0007350; GO:0007298; GO:0001745; GO:0050829; GO:0007425; GO:0007442; GO:0006955; GO:0016021; GO:0045475; GO:0007616; GO:0045824; GO:0008284; GO:0004725; GO:0004888,"JAK-STAT cascade; apical plasma membrane; apicolateral plasma membrane; blastoderm segmentation; border follicle cell migration; compound eye morphogenesis; defense response to Gram-negative bacterium; epithelial cell fate determination, open tracheal system; hindgut morphogenesis; immune response; integral to membrane; locomotor rhythm; long-term memory; negative regulation of innate immune response; positive regulation of cell proliferation; protein tyrosine phosphatase activity; transmembrane signaling receptor activity",PF00041;,,,,,,,,,DOME_DROME,Drosophila melanogaster (Fruit fly),"blastoderm segmentation [GO:0007350]; border follicle cell migration [GO:0007298]; compound eye morphogenesis [GO:0001745]; defense response to Gram-negative bacterium [GO:0050829]; epithelial cell fate determination, open tracheal system [GO:0007425]; epithelium development [GO:0060429]; germarium-derived egg chamber formation [GO:0007293]; hindgut morphogenesis [GO:0007442]; immune response [GO:0006955]; JAK-STAT cascade [GO:0007259]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; morphogenesis of an epithelium [GO:0002009]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; positive regulation of cell proliferation [GO:0008284]; regulation of apoptotic process [GO:0042981]" comp130501_c4_seq1,616,47.8896,0.59610941,8,11,,1.00E-26,Q8TDY8,Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36),Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00041;PF07679;,,,,,,,,,IGDC4_HUMAN,Homo sapiens (Human), comp130501_c4_seq2,500,45.8,0.53624068,0,0,,6.00E-11,Q8NDA2,Hemicentin-2,Hemicentin-2,GO:0005509; GO:0005578; GO:0050896,calcium ion binding; proteinaceous extracellular matrix; response to stimulus,PF12662;PF07645;PF07474;PF07679;,,,,,,,,,HMCN2_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896] comp130502_c0_seq1,1692,36.8794,1.06370546,125,39,,1.00E-47,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130504_c0_seq4,595,38.8235,0.94318988,9,73,,1.00E-40,Q9U8W7,Techylectin-5B,Techylectin-5B,GO:0030246; GO:0016337; GO:0005576; GO:0046872,carbohydrate binding; cell-cell adhesion; extracellular region; metal ion binding,PF00147;,,,,,,,,,TL5B_TACTR,Tachypleus tridentatus (Japanese horseshoe crab),single organismal cell-cell adhesion [GO:0016337] comp130505_c0_seq2,812,51.4778,0.39316122,56,23,,2.00E-103,Q5PRF0,HEAT repeat-containing protein 5A,HEAT repeat-containing protein 5A,,,,,,,,,,,,HTR5A_MOUSE,Mus musculus (Mouse), comp130505_c1_seq1,694,49.8559,0.44174313,13,14,,1.00E-119,Q8C547,HEAT repeat-containing protein 5B,HEAT repeat-containing protein 5B,,,,2.00E-112,CHOYP_HTR5B.1.1,,,,,,,HTR5B_MOUSE,Mus musculus (Mouse), comp130505_c2_seq1,465,47.957,0.56636139,16,21,,1.00E-16,O42998,Pof6 interactor protein 1,Pof6 interactor protein 1,GO:0005794; GO:0007049; GO:0051301; GO:0005829; GO:0030139; GO:0006897; GO:0006886; GO:0005634; GO:0043234; GO:0042147,"Golgi apparatus; cell cycle; cell division; cytosol; endocytic vesicle; endocytosis; intracellular protein transport; nucleus; protein complex; retrograde transport, endosome to Golgi",,,,,,,,,,SIP1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]" comp130506_c0_seq3,1096,36.6788,0.7372318,2,23,,3.00E-12,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp130506_c0_seq7,1053,35.8974,0.80242565,0,9,,2.00E-12,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp130513_c0_seq1,1314,38.6606,0.36965913,6,7,,5.00E-36,Q9UJY5,"ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)","ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)",GO:0005794; GO:0030131; GO:0010008; GO:0006886; GO:0045732; GO:0016192,Golgi apparatus; clathrin adaptor complex; endosome membrane; intracellular protein transport; positive regulation of protein catabolic process; vesicle-mediated transport,PF02883;PF03127;PF00790;,,,,,,,,,GGA1_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; toxin transport [GO:1901998]; vesicle-mediated transport [GO:0016192] comp130513_c0_seq2,1350,38.1481,0.36909227,0,7,,2.00E-13,P22892,AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 subunit gamma-1) (Adaptor protein complex AP-1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1),AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1),GO:0005794; GO:0030131; GO:0030136; GO:0030665; GO:0006897; GO:0006886; GO:0048471; GO:0008565; GO:0005802; GO:0016192,Golgi apparatus; clathrin adaptor complex; clathrin-coated vesicle; clathrin-coated vesicle membrane; endocytosis; intracellular protein transport; perinuclear region of cytoplasm; protein transporter activity; trans-Golgi network; vesicle-mediated transport,PF01602;PF02883;,,,,,,,,,AP1G1_MOUSE,Mus musculus (Mouse),endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192] comp130513_c0_seq3,1345,42.0074,0.39135843,82,111,,3.00E-110,Q8R0H9,"ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)","ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)",GO:0005794; GO:0030131; GO:0010008; GO:0006886; GO:0045732; GO:0016192,Golgi apparatus; clathrin adaptor complex; endosome membrane; intracellular protein transport; positive regulation of protein catabolic process; vesicle-mediated transport,PF02883;PF03127;PF00790;,2.00E-114,CHOYP_F179B.1.1,,,,,,,GGA1_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; toxin transport [GO:1901998]; vesicle-mediated transport [GO:0016192] comp130517_c0_seq1,623,40.4494,0.5228502,13,91,,6.00E-69,Q96F25,UDP-N-acetylglucosamine transferase subunit ALG14 homolog,UDP-N-acetylglucosamine transferase subunit ALG14 homolog,GO:0006488; GO:0005789; GO:0016021; GO:0043687; GO:0018279,dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum membrane; integral to membrane; post-translational protein modification; protein N-linked glycosylation via asparagine,PF08660;,,,1.00E-55,ruditapes_c29808,,,,,ALG14_HUMAN,Homo sapiens (Human),dolichol-linked oligosaccharide biosynthetic process [GO:0006488] comp130518_c0_seq1,1162,34.8537,0.66849152,3,2,,2.00E-31,Q4WPM8,Protein AF-9 homolog,Protein AF-9 homolog,GO:0006281; GO:0016568; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"DNA repair; chromatin modification; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03366;,,,,,,,,,AF9_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),"chromatin modification [GO:0016568]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130518_c0_seq2,1333,34.8087,0.61400414,61,196,,4.00E-96,O95619,YEATS domain-containing protein 4 (Glioma-amplified sequence 41) (Gas41) (NuMA-binding protein 1) (NuBI-1) (NuBI1),YEATS domain-containing protein 4 (Glioma-amplified sequence 41) (Gas41) (NuMA-binding protein 1) (NuBI-1) (NuBI1),GO:0003677; GO:0035267; GO:0043968; GO:0043967; GO:0007067; GO:0016363; GO:0045893; GO:0040008; GO:0003700; GO:0005200; GO:0006351,"DNA binding; NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitosis; nuclear matrix; positive regulation of transcription, DNA-dependent; regulation of growth; sequence-specific DNA binding transcription factor activity; structural constituent of cytoskeleton; transcription, DNA-dependent",PF03366;,8.00E-108,CHOYP_LOC100374387.1.1,,,,,,,YETS4_HUMAN,Homo sapiens (Human),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp130520_c0_seq1,816,43.5049,0.59699543,3,0,,1.00E-55,Q9R0N7,Synaptotagmin-7 (Synaptotagmin VII) (SytVII),Synaptotagmin-7 (Synaptotagmin VII) (SytVII),GO:0030054; GO:0016021; GO:0005764; GO:0046872; GO:0001778; GO:0030672; GO:0005215,cell junction; integral to membrane; lysosome; metal ion binding; plasma membrane repair; synaptic vesicle membrane; transporter activity,PF00168;,9.00E-73,CHOYP_SYT7.1.1,,,,,,,SYT7_MOUSE,Mus musculus (Mouse),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119] comp130520_c0_seq3,1109,43.1019,0.73906704,3,0,,1.00E-54,Q9R0N7,Synaptotagmin-7 (Synaptotagmin VII) (SytVII),Synaptotagmin-7 (Synaptotagmin VII) (SytVII),GO:0030054; GO:0016021; GO:0005764; GO:0046872; GO:0001778; GO:0030672; GO:0005215,cell junction; integral to membrane; lysosome; metal ion binding; plasma membrane repair; synaptic vesicle membrane; transporter activity,PF00168;,,,,,,,,,SYT7_MOUSE,Mus musculus (Mouse),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119] comp130521_c0_seq1,1014,37.2781,0.56886702,843,41,,1.00E-47,A6NJI9,Leucine-rich repeat-containing protein 72,Leucine-rich repeat-containing protein 72,,,,2.00E-44,CHOYP_LOC100370463.1.1,,,,,,,LRC72_HUMAN,Homo sapiens (Human),melanocyte differentiation [GO:0030318] comp130527_c0_seq1,490,47.3469,0.99977792,0,18,,,,,,,,,3.00E-19,CHOYP_LOC373275.7.7,,,,,,,,, comp130527_c0_seq2,487,49.692,0.94417203,6,111,,3.00E-91,P86221,Tubulin beta-4B chain (Tubulin beta-2C chain) (Fragments),Tubulin beta-4B chain (Tubulin beta-2C chain) (Fragments),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;,1.00E-118,CHOYP_TBB.3.7,5.00E-115,ruditapes_c6496,,,,,TBB4B_MESAU,Mesocricetus auratus (Golden hamster),microtubule-based process [GO:0007017] comp130529_c0_seq1,1324,45.3927,0.86747425,161,56,,2.00E-115,Q9GKL8,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08246;PF00112;,2.00E-90,CHOYP_LOC575203.6.6,3.00E-162,ruditapes_c4044,,,,,CATL1_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),viral entry into host cell [GO:0046718] comp130529_c0_seq2,651,44.2396,0.81945376,11,9,,2.00E-69,Q26636,Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],GO:0030154; GO:0008234; GO:0005764; GO:0007275; GO:0006508,cell differentiation; cysteine-type peptidase activity; lysosome; multicellular organismal development; proteolysis,PF08246;PF00112;,1.00E-44,CHOYP_CTSL2.1.2,2.00E-46,ruditapes_lrc33876,,,,,CATL_SARPE,Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp130535_c0_seq1,352,44.6023,0.77912344,0,10,,5.00E-11,Q8MP06,Senecionine N-oxygenase (SNO) (EC 1.14.13.101),Senecionine N-oxygenase (SNO) (EC 1.14.13.101),GO:0004499; GO:0050661; GO:0009820; GO:0005576; GO:0050660; GO:0051289; GO:0033784,"N,N-dimethylaniline monooxygenase activity; NADP binding; alkaloid metabolic process; extracellular region; flavin adenine dinucleotide binding; protein homotetramerization; senecionine N-oxygenase activity",PF00743;,,,,,,,,,SNO1_TYRJA,Tyria jacobaeae (Cinnabar moth),alkaloid metabolic process [GO:0009820]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289] comp130537_c0_seq1,591,43.6548,0.7145691,5,37,,8.00E-116,P23228,"Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)","Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)",GO:0006695; GO:0005737; GO:0004421; GO:0008299,cholesterol biosynthetic process; cytoplasm; hydroxymethylglutaryl-CoA synthase activity; isoprenoid biosynthetic process,PF08540;PF01154;,5.00E-87,CHOYP_LOC100375733.1.1,,,,,,,HMCS1_CHICK,Gallus gallus (Chicken),cholesterol biosynthetic process [GO:0006695]; isoprenoid biosynthetic process [GO:0008299] comp130538_c0_seq1,1077,40.2043,0.99621835,12,292,,4.00E-08,Q9Y575,Ankyrin repeat and SOCS box protein 3 (ASB-3),Ankyrin repeat and SOCS box protein 3 (ASB-3),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF13606;PF07525;,,,,,,,,,ASB3_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp130539_c0_seq1,2180,38.6697,0.42396496,2375,1749,,5.00E-151,Q9JHS4,"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial","ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial",GO:0005524; GO:0004176; GO:0016887; GO:0046872; GO:0009841; GO:0005743; GO:0042645; GO:0016504; GO:0006457; GO:0051603,ATP binding; ATP-dependent peptidase activity; ATPase activity; metal ion binding; mitochondrial endopeptidase Clp complex; mitochondrial inner membrane; mitochondrial nucleoid; peptidase activator activity; protein folding; proteolysis involved in cellular protein catabolic process,PF07724;PF10431;,2.00E-17,CHOYP_CLPX.1.2,3.00E-24,ruditapes_c12422,,,,,CLPX_MOUSE,Mus musculus (Mouse),protein catabolic process [GO:0030163]; protein folding [GO:0006457]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp130547_c0_seq1,1320,38.9394,0.90351609,1,491,female>male,6.00E-06,P35479,Leukocyte cysteine proteinase inhibitor 1 (PLCPI) (Stefin-D1),Leukocyte cysteine proteinase inhibitor 1 (PLCPI) (Stefin-D1),GO:0004869; GO:0005737; GO:0010951,cysteine-type endopeptidase inhibitor activity; cytoplasm; negative regulation of endopeptidase activity,PF00031;,,,,,,,,,CPI1_PIG,Sus scrofa (Pig), comp130548_c1_seq1,731,36.7989,0.42366094,51,254,,3.00E-15,Q6ZUT1,Uncharacterized protein C11orf57,Uncharacterized protein C11orf57,,,,,,,,,,,,CK057_HUMAN,Homo sapiens (Human), comp130552_c0_seq1,3164,37.1365,0.62024924,234,597,,3.00E-08,P08199,Nucleolin (Protein C23),Nucleolin (Protein C23),GO:0003723; GO:0005737; GO:0005730; GO:0000166; GO:0030529; GO:0042162,RNA binding; cytoplasm; nucleolus; nucleotide binding; ribonucleoprotein complex; telomeric DNA binding,PF00076;,2.00E-81,CHOYP_AAEL_AAEL015585.3.3,,,,,,,NUCL_MESAU,Mesocricetus auratus (Golden hamster), comp130552_c0_seq2,3210,37.0093,0.61606401,53,467,,9.00E-64,Q66II8,U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70),U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70),GO:0003723; GO:0000398; GO:0016607; GO:0000166; GO:0043484; GO:0005681,"RNA binding; mRNA splicing, via spliceosome; nuclear speck; nucleotide binding; regulation of RNA splicing; spliceosomal complex",PF00076;PF12220;,3.00E-117,CHOYP_LOC662320.2.2,,,,,,,RU17_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"hematopoietic stem cell differentiation [GO:0060218]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]" comp130558_c0_seq1,1579,30.779,0.42954497,275,633,,,,,,,,,1.00E-11,CHOYP_LOC594361.1.2,,,,,,,,, comp130564_c0_seq1,376,44.6809,0.92136937,5,53,,2.00E-21,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp130569_c1_seq1,1157,38.9801,0.62632258,9,44,,2.00E-27,O43399,Tumor protein D54 (hD54) (Tumor protein D52-like 2),Tumor protein D54 (hD54) (Tumor protein D52-like 2),GO:0048471; GO:0042803; GO:0042127,perinuclear region of cytoplasm; protein homodimerization activity; regulation of cell proliferation,PF04201;,5.00E-53,CHOYP_AGAP_AGAP004868.1.1,,,,,,,TPD54_HUMAN,Homo sapiens (Human),regulation of cell proliferation [GO:0042127] comp130569_c1_seq2,748,35.9626,0.54549117,0,0,,,,,,,,,,,7.00E-15,ruditapes_c30500,,,,,,, comp130569_c1_seq3,1097,39.1978,0.583836,4,2,,4.00E-19,P55327,Tumor protein D52 (Protein N8),Tumor protein D52 (Protein N8),GO:0030183; GO:0009653; GO:0005509; GO:0005783; GO:0048471; GO:0046982; GO:0042803; GO:0046903,B cell differentiation; anatomical structure morphogenesis; calcium ion binding; endoplasmic reticulum; perinuclear region of cytoplasm; protein heterodimerization activity; protein homodimerization activity; secretion,PF04201;,8.00E-37,CHOYP_LOC100878467.3.4,,,,,,,TPD52_HUMAN,Homo sapiens (Human),anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; secretion [GO:0046903] comp130572_c0_seq2,1173,45.6948,0.52882921,5,0,,2.00E-83,Q5PQP1,"RNA-binding motif, single-stranded-interacting protein 1","RNA-binding motif, single-stranded-interacting protein 1",GO:0003677; GO:0006260; GO:0003723; GO:0000166; GO:0005634,DNA binding; DNA replication; RNA binding; nucleotide binding; nucleus,PF00076;,,,,,,,,,RBMS1_RAT,Rattus norvegicus (Rat),DNA replication [GO:0006260] comp130572_c0_seq4,1140,44.7368,0.52935213,5,0,,2.00E-83,Q3ZBP3,"RNA-binding motif, single-stranded-interacting protein 1","RNA-binding motif, single-stranded-interacting protein 1",GO:0003677; GO:0006260; GO:0003723; GO:0000166; GO:0005634,DNA binding; DNA replication; RNA binding; nucleotide binding; nucleus,PF00076;,5.00E-128,CHOYP_SHEP.1.1,,,,,,,RBMS1_BOVIN,Bos taurus (Bovine),DNA replication [GO:0006260] comp130572_c0_seq5,1351,43.8194,0.57204967,0,0,,8.00E-69,B4MM23,Protein alan shepard,Protein alan shepard,GO:0003723; GO:0000166; GO:0009629,RNA binding; nucleotide binding; response to gravity,PF00076;,3.00E-125,CHOYP_LOC100744046.2.2,,,,,,,SHEP_DROWI,Drosophila willistoni (Fruit fly),response to gravity [GO:0009629] comp130572_c0_seq8,818,45.11,0.55357435,0,0,,,,,,,,,2.00E-24,CHOYP_SHEP.1.1,,,,,,,,, comp130580_c1_seq1,412,49.7573,0.75481399,2,0,,,,,,,,,1.00E-11,CHOYP_LOC562156.1.2,,,,,,,,, comp130580_c1_seq2,1974,44.2756,0.98261819,119,18,,3.00E-17,Q86UP6,CUB and zona pellucida-like domain-containing protein 1 (CUB and ZP domain-containing protein 1) (Transmembrane protein UO-44),CUB and zona pellucida-like domain-containing protein 1 (CUB and ZP domain-containing protein 1) (Transmembrane protein UO-44),GO:0007049; GO:0051301; GO:0008283; GO:0016021; GO:0006931; GO:0030658; GO:0032023; GO:0042589,"cell cycle; cell division; cell proliferation; integral to membrane; substrate-dependent cell migration, cell attachment to substrate; transport vesicle membrane; trypsinogen activation; zymogen granule membrane",PF00431;PF00100;,5.00E-11,CHOYP_LOC562156.2.2,,,,,,,CUZD1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; substrate-dependent cell migration, cell attachment to substrate [GO:0006931]; trypsinogen activation [GO:0032023]" comp130580_c2_seq2,495,44.8485,0.66150141,12,8,,7.00E-12,Q5RDA4,Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein),Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein),GO:0007155; GO:0016020; GO:0005578; GO:0005044,cell adhesion; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00530;,,,,,,,,,LG3BP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell adhesion [GO:0007155] comp130583_c0_seq1,1747,41.557,0.55921106,156,72,,7.00E-09,Q8YTC2,Uncharacterized WD repeat-containing protein alr2800,Uncharacterized WD repeat-containing protein alr2800,GO:0043531; GO:0006952; GO:0006355,"ADP binding; defense response; regulation of transcription, DNA-dependent",PF00931;PF00400;,2.00E-72,CHOYP_LOC100367460.1.1,,,,,,,Y2800_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp130586_c0_seq1,1119,34.7632,0.42293825,1449,7604,,8.00E-48,Q90673,"PRELI domain-containing protein 1, mitochondrial (Px19-like protein)","PRELI domain-containing protein 1, mitochondrial (Px19-like protein)",GO:0005739,mitochondrion,PF04707;,,,,,,,,,PRLD1_CHICK,Gallus gallus (Chicken),apoptotic process [GO:0006915] comp130588_c0_seq1,2145,49.324,0.55547898,78,40,,1.00E-06,Q54T86,WW domain-containing protein A,WW domain-containing protein A,GO:0007015; GO:0005516; GO:0005938; GO:0005856; GO:0000281; GO:0005730; GO:0005634; GO:0042787; GO:0004842,actin filament organization; calmodulin binding; cell cortex; cytoskeleton; mitotic cytokinesis; nucleolus; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00168;PF00397;,4.00E-57,CHOYP_LOC100546505.1.1,,,,,,,DWWA_DICDI,Dictyostelium discoideum (Slime mold),actin filament organization [GO:0007015]; mitotic cytokinesis [GO:0000281] comp130588_c1_seq1,1715,41.4577,0.40324137,55,145,,0,Q9P2P5,"E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)","E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)",GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00168;PF00632;PF16562;PF00397;,0,CHOYP_LOC100546505.1.1,,,,,,,HECW2_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp130588_c1_seq2,698,40.4011,0.2817844,2,7,,9.00E-96,Q9P2P5,"E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)","E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)",GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00168;PF00632;PF16562;PF00397;,2.00E-11,CHOYP_NEDD4L.1.1,,,,,,,HECW2_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp130594_c0_seq1,472,40.4661,0.74572407,29,32,,,,,,,,,1.00E-18,CHOYP_PHUM_PHUM527880.1.1,2.00E-26,ruditapes_c10649,,,,,,, comp130594_c0_seq2,437,38.2151,0.5140872,15,23,,2.00E-27,Q96B42,Transmembrane protein 18,Transmembrane protein 18,GO:0003677; GO:0016477; GO:0005737; GO:0016021; GO:0031965; GO:0006351,"DNA binding; cell migration; cytoplasm; integral to membrane; nuclear membrane; transcription, DNA-dependent",PF14770;,,,,,,,,,TMM18_HUMAN,Homo sapiens (Human),"cell migration [GO:0016477]; transcription, DNA-templated [GO:0006351]" comp130596_c1_seq1,1150,39.4783,0.50482494,0,0,,1.00E-19,Q9FJR0,Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-) (ATP-dependent helicase UPF1),Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-) (ATP-dependent helicase UPF1),GO:0005524; GO:0003677; GO:0003723; GO:0016246; GO:0000932; GO:0005829; GO:0042742; GO:0004386; GO:0009867; GO:0048571; GO:0000184; GO:0005886; GO:0009506; GO:0009744; GO:0009611; GO:0009863; GO:0010182; GO:0008270,"ATP binding; DNA binding; RNA binding; RNA interference; cytoplasmic mRNA processing body; cytosol; defense response to bacterium; helicase activity; jasmonic acid mediated signaling pathway; long-day photoperiodism; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; plasma membrane; plasmodesma; response to sucrose stimulus; response to wounding; salicylic acid mediated signaling pathway; sugar mediated signaling pathway; zinc ion binding",PF09416;,,,,,,,,,RENT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; long-day photoperiodism [GO:0048571]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; response to wounding [GO:0009611]; salicylic acid mediated signaling pathway [GO:0009863]; sugar mediated signaling pathway [GO:0010182]" comp130596_c1_seq2,1337,40.9125,0.4211004,6,29,,4.00E-81,E1BMP7,DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],GO:0051539; GO:0043139; GO:0017108; GO:0005524; GO:0003677; GO:0000729; GO:0000076; GO:0033567; GO:0043137; GO:0006284; GO:0005760; GO:0046872; GO:0043504; GO:0006264; GO:0042645; GO:0005634; GO:0045740; GO:0043142; GO:0016890,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; 5'-flap endonuclease activity; ATP binding; DNA binding; DNA double-strand break processing; DNA replication checkpoint; DNA replication, Okazaki fragment processing; DNA replication, removal of RNA primer; base-excision repair; gamma DNA polymerase complex; metal ion binding; mitochondrial DNA repair; mitochondrial DNA replication; mitochondrial nucleoid; nucleus; positive regulation of DNA replication; single-stranded DNA-dependent ATPase activity; site-specific endodeoxyribonuclease activity, specific for altered base",PF08696;,3.00E-31,CHOYP_DNA2.1.5,,,,,,,DNA2_BOVIN,Bos taurus (Bovine),"DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication checkpoint [GO:0000076]" comp130597_c0_seq1,1045,44.1148,0.6355288,78,86,,1.00E-53,Q05192,Nuclear hormone receptor FTZ-F1 beta (Nuclear hormone receptor HR39) (dHR39) (Nuclear receptor subfamily 5 group B member 1),Nuclear hormone receptor FTZ-F1 beta (Nuclear hormone receptor HR39) (dHR39) (Nuclear receptor subfamily 5 group B member 1),GO:0000978; GO:0006919; GO:0035072; GO:0016321; GO:0004879; GO:0045433; GO:0005634; GO:0060968; GO:0035211; GO:0003707; GO:0008270,"RNA polymerase II core promoter proximal region sequence-specific DNA binding; activation of cysteine-type endopeptidase activity involved in apoptotic process; ecdysone-mediated induction of salivary gland cell autophagic cell death; female meiosis chromosome segregation; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; male courtship behavior, veined wing generated song production; nucleus; regulation of gene silencing; spermathecum morphogenesis; steroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,,,,,,,,,FTF1B_DROME,Drosophila melanogaster (Fruit fly),"female meiosis chromosome segregation [GO:0016321]; hormone-mediated signaling pathway [GO:0009755]; male courtship behavior, veined wing generated song production [GO:0045433]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene silencing [GO:0060968]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; spermathecum morphogenesis [GO:0035211]; tissue development [GO:0009888]; transcription, DNA-templated [GO:0006351]" comp130601_c0_seq1,777,43.758,0.70786791,14,30,,7.00E-23,Q91ZT7,Ankyrin repeat and SOCS box protein 10 (ASB-10),Ankyrin repeat and SOCS box protein 10 (ASB-10),GO:0005737; GO:0035556; GO:0005634; GO:0016567,cytoplasm; intracellular signal transduction; nucleus; protein ubiquitination,PF00023;PF12796;PF07525;,,,,,,,,,ASB10_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556] comp130601_c0_seq2,670,45.0746,0.6269089,11,20,,5.00E-22,Q9VCA8,Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein),Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein),GO:0003723; GO:0019730; GO:0051298; GO:0001751; GO:0005811; GO:0043066; GO:0046427; GO:0007169,RNA binding; antimicrobial humoral response; centrosome duplication; compound eye photoreceptor cell differentiation; lipid particle; negative regulation of apoptotic process; positive regulation of JAK-STAT cascade; transmembrane receptor protein tyrosine kinase signaling pathway,PF12796;PF00013;,,,,,,,,,ANKHM_DROME,Drosophila melanogaster (Fruit fly),antimicrobial humoral response [GO:0019730]; cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; compound eye photoreceptor cell differentiation [GO:0001751]; negative regulation of apoptotic process [GO:0043066]; positive regulation of JAK-STAT cascade [GO:0046427]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp130602_c0_seq1,3607,32.3538,0.60806117,3782,24045,,9.00E-09,Q76B49,CD63 antigen (CD antigen CD63),CD63 antigen (CD antigen CD63),GO:0009986; GO:0034613; GO:0016021; GO:0031902; GO:0005765; GO:0005886; GO:2000680,cell surface; cellular protein localization; integral to membrane; late endosome membrane; lysosomal membrane; plasma membrane; regulation of rubidium ion transport,PF00335;,3.00E-36,CHOYP_BRAFLDRAFT_124708.2.2,2.00E-22,ruditapes_c8602,,,,,CD63_FELCA,Felis catus (Cat) (Felis silvestris catus),cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] comp130607_c3_seq1,391,42.4552,0.6864192,0,0,,8.00E-10,Q99MZ6,Unconventional myosin-VIIb,Unconventional myosin-VIIb,GO:0005524; GO:0016324; GO:0003774; GO:0016459,ATP binding; apical plasma membrane; motor activity; myosin complex,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7B_MOUSE,Mus musculus (Mouse),brush border assembly [GO:1904970]; cell differentiation [GO:0030154] comp130607_c3_seq2,589,45.6706,0.61974969,8,20,,4.00E-58,P59281,Rho GTPase-activating protein 39,Rho GTPase-activating protein 39,GO:0005856; GO:0005634; GO:0007165,cytoskeleton; nucleus; signal transduction,PF00784;PF00620;,6.00E-35,CHOYP_BRAFLDRAFT_102618.1.1,,,,,,,RHG39_MOUSE,Mus musculus (Mouse),signal transduction [GO:0007165] comp130607_c4_seq1,419,45.8234,0.54693746,17,30,,1.00E-10,Q55DK5,Mental retardation GTPase activating protein homolog 3 (GTPase activating factor for raC protein AA) (Rho GTPase-activating protein gacAA),Mental retardation GTPase activating protein homolog 3 (GTPase activating factor for raC protein AA) (Rho GTPase-activating protein gacAA),GO:0005096; GO:0000331; GO:0043547; GO:0007165,GTPase activator activity; contractile vacuole; positive regulation of GTPase activity; signal transduction,PF00611;PF00620;,6.00E-21,CHOYP_RHG39.1.1,2.00E-81,ruditapes_c17550,,,,,MGP3_DICDI,Dictyostelium discoideum (Slime mold),signal transduction [GO:0007165] comp130608_c0_seq1,2056,40.321,0.35089183,90,107,,1.00E-14,Q9D4J7,PHD finger protein 6,PHD finger protein 6,GO:0005730; GO:0006355; GO:0006351; GO:0008270,"nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,PHF6_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130611_c0_seq1,583,46.8268,0.57593858,22,61,,4.00E-52,Q0JKD0,"Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)","Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)",GO:0051538; GO:0010181; GO:0097054; GO:0019676; GO:0009507; GO:0048589; GO:0050660; GO:0006537; GO:0016040; GO:0005506; GO:0009536; GO:0060359,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; ammonia assimilation cycle; chloroplast; developmental growth; flavin adenine dinucleotide binding; glutamate biosynthetic process; glutamate synthase (NADH) activity; iron ion binding; plastid; response to ammonium ion",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,,,8.00E-19,ruditapes_c21661,,,,,GLT1_ORYSJ,Oryza sativa subsp. japonica (Rice),ammonia assimilation cycle [GO:0019676]; developmental growth [GO:0048589]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]; response to ammonium ion [GO:0060359] comp130611_c1_seq3,534,46.6292,0.45487406,13,27,,2.00E-56,Q12680,Glutamate synthase [NADH] (EC 1.4.1.14) (NADH-GOGAT),Glutamate synthase [NADH] (EC 1.4.1.14) (NADH-GOGAT),GO:0051538; GO:0010181; GO:0097054; GO:0019676; GO:0050660; GO:0006537; GO:0016040; GO:0005506,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; ammonia assimilation cycle; flavin adenine dinucleotide binding; glutamate biosynthetic process; glutamate synthase (NADH) activity; iron ion binding",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,3.00E-64,CHOYP_BRAFLDRAFT_129259.1.1,,,,,,,GLT1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054] comp130621_c0_seq2,864,40.7407,0.72795048,13,57,,3.00E-82,Q5U367,"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3)","Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3)",GO:0031418; GO:0070831; GO:0032870; GO:0030199; GO:0001886; GO:0048730; GO:0001701; GO:0005506; GO:0060425; GO:0021915; GO:0033823; GO:0008475; GO:0008104; GO:0030867; GO:0042311,L-ascorbic acid binding; basement membrane assembly; cellular response to hormone stimulus; collagen fibril organization; endothelial cell morphogenesis; epidermis morphogenesis; in utero embryonic development; iron ion binding; lung morphogenesis; neural tube development; procollagen glucosyltransferase activity; procollagen-lysine 5-dioxygenase activity; protein localization; rough endoplasmic reticulum membrane; vasodilation,,2.00E-37,CHOYP_PLOD3.1.1,,,,,,,PLOD3_RAT,Rattus norvegicus (Rat),basement membrane assembly [GO:0070831]; cellular response to hormone stimulus [GO:0032870]; collagen fibril organization [GO:0030199]; endothelial cell morphogenesis [GO:0001886]; epidermis morphogenesis [GO:0048730]; in utero embryonic development [GO:0001701]; lung morphogenesis [GO:0060425]; neural tube development [GO:0021915]; protein localization [GO:0008104]; vasodilation [GO:0042311] comp130622_c0_seq1,999,41.041,0.40700081,26,36,,3.00E-57,Q96IK5,Germ cell-less protein-like 1,Germ cell-less protein-like 1,GO:0030154; GO:0007275; GO:0005635; GO:0016363; GO:0006355; GO:0007283,"cell differentiation; multicellular organismal development; nuclear envelope; nuclear matrix; regulation of transcription, DNA-dependent; spermatogenesis",PF07707;PF00651;,,,,,,,,,GMCL1_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]" comp130623_c0_seq1,809,31.2732,0.55750304,37,6,,8.00E-40,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,4.00E-52,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp130631_c0_seq1,1184,35.8108,0.48788891,46,326,,6.00E-27,P38166,Protein transport protein SFT2,Protein transport protein SFT2,GO:0000139; GO:0006895; GO:0016021; GO:0015031,Golgi membrane; Golgi to endosome transport; integral to membrane; protein transport,PF04178;,2.00E-45,CHOYP_ISCW_ISCW017655.1.1,,,,,,,SFT2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp130634_c0_seq2,3109,30.9746,0.38335905,520,2051,,1.00E-19,Q62785,28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1),28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1),,,PF10252;,,,,,,,,,HAP28_RAT,Rattus norvegicus (Rat), comp130638_c1_seq1,1163,45.3138,0.54527928,13,170,,6.00E-48,Q9VN14,Contactin,Contactin,GO:0031225; GO:0008366; GO:0030246; GO:0061343; GO:0060857; GO:0045197; GO:0021682; GO:0005886; GO:0005918; GO:0019991,anchored to membrane; axon ensheathment; carbohydrate binding; cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; establishment or maintenance of epithelial cell apical/basal polarity; nerve maturation; plasma membrane; septate junction; septate junction assembly,PF00041;PF00047;PF00059;,,,,,,,,,CONT_DROME,Drosophila melanogaster (Fruit fly),axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] comp130639_c0_seq1,872,49.7706,0.61367638,59,49,,1.00E-13,Q2KHM9,Uncharacterized protein KIAA0753,Protein moonraker (MNR),GO:0005813; GO:0005737,centrosome; cytoplasm,PF15718;,2.00E-24,CHOYP_LOC100377435.1.1,,,,,,,K0753_HUMAN,Homo sapiens (Human),centriole replication [GO:0007099]; protein localization to centrosome [GO:0071539] comp130644_c0_seq1,349,43.553,0.61457923,41,3,,,,,,,,,3.00E-30,CHOYP_LOC101154902.1.1,,,,,,,,, comp130645_c0_seq1,415,43.6145,0.66193775,9,12,,2.00E-20,Q7YR43,Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Discoidin receptor tyrosine kinase) (Tyrosine kinase DDR) (CD antigen CD167a),Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Discoidin receptor tyrosine kinase) (Tyrosine kinase DDR) (CD antigen CD167a),GO:0005524; GO:0060444; GO:0005518; GO:0043583; GO:0007566; GO:0016021; GO:0007595; GO:0060749; GO:0046872; GO:0008285; GO:0038083; GO:0005886; GO:0038062; GO:0001558; GO:0001952; GO:0010715; GO:0014909; GO:0061302; GO:0044319,"ATP binding; branching involved in mammary gland duct morphogenesis; collagen binding; ear development; embryo implantation; integral to membrane; lactation; mammary gland alveolus development; metal ion binding; negative regulation of cell proliferation; peptidyl-tyrosine autophosphorylation; plasma membrane; protein tyrosine kinase collagen receptor activity; regulation of cell growth; regulation of cell-matrix adhesion; regulation of extracellular matrix disassembly; smooth muscle cell migration; smooth muscle cell-matrix adhesion; wound healing, spreading of cells",PF00754;PF07714;,,,,,,,,,DDR1_PANTR,Pan troglodytes (Chimpanzee),"branching involved in mammary gland duct morphogenesis [GO:0060444]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell proliferation [GO:0008285]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; wound healing, spreading of cells [GO:0044319]" comp130645_c1_seq1,348,44.8276,0.40825872,12,8,,5.00E-37,P07949,Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment],Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment],GO:0005524; GO:0000165; GO:0061146; GO:0005509; GO:0071300; GO:0001838; GO:0010008; GO:0048484; GO:0007156; GO:0005887; GO:0097021; GO:0033619; GO:0001755; GO:0007158; GO:0042551; GO:0033630; GO:0030335; GO:2001241; GO:0072300; GO:0010976; GO:0045893; GO:0007497; GO:0004713; GO:0004872; GO:0048265; GO:0007165; GO:0004714; GO:0007169; GO:0035799; GO:0001657,"ATP binding; MAPK cascade; Peyer's patch morphogenesis; calcium ion binding; cellular response to retinoic acid; embryonic epithelial tube formation; endosome membrane; enteric nervous system development; homophilic cell adhesion; integral to plasma membrane; lymphocyte migration into lymphoid organs; membrane protein proteolysis; neural crest cell migration; neuron cell-cell adhesion; neuron maturation; positive regulation of cell adhesion mediated by integrin; positive regulation of cell migration; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of metanephric glomerulus development; positive regulation of neuron projection development; positive regulation of transcription, DNA-dependent; posterior midgut development; protein tyrosine kinase activity; receptor activity; response to pain; signal transduction; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway; ureter maturation; ureteric bud development",PF00028;PF07714;,3.00E-18,CHOYP_LOC100376764.1.1,,,,,,,RET_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of serine phosphorylation of STAT3 protein [GO:1903263]; positive regulation of transcription, DNA-templated [GO:0045893]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to drug [GO:0042493]; response to pain [GO:0048265]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ureter maturation [GO:0035799]" comp130646_c0_seq1,1157,40.7952,0.70702371,0,0,,3.00E-88,Q9GKX6,Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase),Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase),GO:0004034; GO:0030246; GO:0005737; GO:0019318,aldose 1-epimerase activity; carbohydrate binding; cytoplasm; hexose metabolic process,PF01263;,,,,,,,,,GALM_PIG,Sus scrofa (Pig),galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006] comp130646_c0_seq3,1091,41.6132,0.72052691,0,0,,2.00E-19,P40801,Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase); Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)],Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase); Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)],GO:0003978; GO:0004034; GO:0030246; GO:0044237; GO:0050662; GO:0006012,UDP-glucose 4-epimerase activity; aldose 1-epimerase activity; carbohydrate binding; cellular metabolic process; coenzyme binding; galactose metabolic process,PF01263;PF16363;,1.00E-40,CHOYP_BRAFLDRAFT_284587.3.3,4.00E-45,ruditapes_c1431,,,,,GAL10_PACTA,Pachysolen tannophilus (Yeast),galactose metabolic process [GO:0006012] comp130649_c0_seq1,1779,39.6852,0.56231944,35,57,,1.00E-97,Q99PL6,UBX domain-containing protein 6 (UBX domain-containing protein 1),UBX domain-containing protein 6 (UBX domain-containing protein 1),GO:0005737; GO:0005815; GO:0005730,cytoplasm; microtubule organizing center; nucleolus,PF09409;PF00789;,,,,,,,,,UBXN6_MOUSE,Mus musculus (Mouse), comp130649_c0_seq2,1213,39.5713,0.46692339,0,0,,6.00E-09,Q8VBT9,Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog),Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog),GO:0030659; GO:0005829; GO:0012505; GO:0019898; GO:0042593; GO:0009898; GO:0006886; GO:0005634; GO:0048471; GO:0046324,cytoplasmic vesicle membrane; cytosol; endomembrane system; extrinsic to membrane; glucose homeostasis; internal side of plasma membrane; intracellular protein transport; nucleus; perinuclear region of cytoplasm; regulation of glucose import,PF11470;PF00789;,5.00E-53,CHOYP_LOC100524481.1.1,,,,,,,ASPC1_MOUSE,Mus musculus (Mouse),glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; regulation of glucose import [GO:0046324] comp130651_c0_seq1,1314,40.6393,0.69661433,849,2789,,4.00E-23,Q9C086,INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4),INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4),GO:0006310; GO:0006281; GO:0031011; GO:0005737; GO:0046872; GO:0005730; GO:0005886; GO:0006355; GO:0006351,"DNA recombination; DNA repair; Ino80 complex; cytoplasm; metal ion binding; nucleolus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04795;PF04438;,7.00E-26,CHOYP_BRAFLDRAFT_200162.4.4,,,,,,,IN80B_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130656_c0_seq1,585,37.6068,0.44786136,163,1652,,1.00E-21,Q5VUM1,UPF0369 protein C6orf57,"Succinate dehydrogenase assembly factor 4, mitochondrial (SDH assembly factor 4) (SDHAF4)",GO:0005576; GO:0005739,extracellular region; mitochondrion,PF07896;,,,1.00E-34,ruditapes2_c1785,,,,,CF057_HUMAN,Homo sapiens (Human),innate immune response [GO:0045087] comp130657_c1_seq1,596,38.4228,0.82093432,1,21,,4.00E-32,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp130657_c3_seq1,253,41.1067,1.13100097,3,19,,1.00E-19,O14917,Protocadherin-17 (Protocadherin-68),Protocadherin-17 (Protocadherin-68),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;,,,,,,,,,PCD17_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of synaptic transmission [GO:0050805]; presynaptic active zone assembly [GO:1904071]; regulation of synaptic vesicle clustering [GO:2000807] comp130658_c0_seq1,1622,42.6634,0.78728106,0,2,,1.00E-110,Q9Y2U5,Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2),Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2),GO:0005524; GO:0004709; GO:0007257; GO:0000186; GO:0071260; GO:0005737; GO:0046872; GO:0005634; GO:0045893; GO:0004674,"ATP binding; MAP kinase kinase kinase activity; activation of JUN kinase activity; activation of MAPKK activity; cellular response to mechanical stimulus; cytoplasm; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; protein serine/threonine kinase activity",PF00564;PF00069;,9.00E-45,CHOYP_M3K2.1.1,,,,,,,M3K2_HUMAN,Homo sapiens (Human),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; cellular response to mechanical stimulus [GO:0071260]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]" comp130658_c0_seq2,1993,43.703,0.6996493,15,28,,2.00E-10,Q01973,"Tyrosine-protein kinase transmembrane receptor ROR1 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1)","Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)",GO:0005524; GO:0005737; GO:0005887; GO:0004714; GO:0007169,ATP binding; cytoplasm; integral to plasma membrane; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF01392;PF07679;PF00051;PF07714;,,,,,,,,,ROR1_HUMAN,Homo sapiens (Human),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp130658_c0_seq3,532,39.8496,0.91730397,0,0,,5.00E-07,A2YCH5,Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23),Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23),GO:0005524; GO:0042023; GO:0008353; GO:0019912; GO:0004693; GO:0005829; GO:0010078; GO:0000278; GO:0045736; GO:0005634; GO:0010440,ATP binding; DNA endoreduplication; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein kinase activating kinase activity; cyclin-dependent protein serine/threonine kinase activity; cytosol; maintenance of root meristem identity; mitotic cell cycle; negative regulation of cyclin-dependent protein serine/threonine kinase activity; nucleus; stomatal lineage progression,PF00069;,,,,,,,,,CDKF1_ORYSI,Oryza sativa subsp. indica (Rice),maintenance of root meristem identity [GO:0010078] comp130659_c0_seq4,2047,42.892,0.59827763,1,0,,3.00E-85,A5D6U8,Iron/zinc purple acid phosphatase-like protein (EC 3.1.3.2),Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form),GO:0003993; GO:0005576; GO:0046872,acid phosphatase activity; extracellular region; metal ion binding,PF00149;PF14008;PF16656;,1.00E-49,CHOYP_LOC100370821.2.2,,,,,,,PAPL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130659_c0_seq5,1459,42.8376,0.51320248,0,0,,1.00E-75,A5D6U8,Iron/zinc purple acid phosphatase-like protein (EC 3.1.3.2),Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form),GO:0003993; GO:0005576; GO:0046872,acid phosphatase activity; extracellular region; metal ion binding,PF00149;PF14008;PF16656;,1.00E-49,CHOYP_LOC100370821.2.2,,,,,,,PAPL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130662_c0_seq1,604,45.3642,0.51577294,19,20,,1.00E-13,Q0VDD8,"Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14)","Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14)",GO:0005524; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF03028;PF12777;,,,,,,,,,DYH14_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp130662_c2_seq2,2241,45.3815,0.5379621,89,401,,0,Q96JB1,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DNAH5.2.2,2.00E-71,ruditapes_c9858,,,,,DYH8_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp130663_c0_seq1,531,47.2693,0.48226019,10,16,,,,,,,,,6.00E-16,CHOYP_LOC101079642.1.1,,,,,,,,, comp130664_c0_seq2,688,42.8779,0.88674576,7,117,,6.00E-43,Q91WL5,Cytochrome P450 4A12A (EC 1.14.14.1) (CYPIVA12),Cytochrome P450 4A12A (EC 1.14.14.1) (CYPIVA12),GO:0018685; GO:0070330; GO:0005789; GO:0006631; GO:0020037; GO:0005506,alkane 1-monooxygenase activity; aromatase activity; endoplasmic reticulum membrane; fatty acid metabolic process; heme binding; iron ion binding,PF00067;,,,,,,,,,CP4CA_MOUSE,Mus musculus (Mouse),fatty acid metabolic process [GO:0006631] comp130670_c0_seq1,752,43.617,0.61739823,30,372,,7.00E-13,Q3ZBM4,Integrin beta-1-binding protein 1,Integrin beta-1-binding protein 1,GO:0005092; GO:0007219; GO:0032148; GO:0031214; GO:0002043; GO:0030154; GO:0007160; GO:0044344; GO:0035924; GO:0005856; GO:0005829; GO:0033622; GO:0005178; GO:0007229; GO:0030027; GO:0051451; GO:0070373; GO:0006933; GO:0090051; GO:0008285; GO:0010764; GO:0051895; GO:0032091; GO:0006469; GO:0090315; GO:1900025; GO:0005634; GO:0048471; GO:0005886; GO:0045747; GO:0051781; GO:0008284; GO:0010595; GO:0051894; GO:0051897; GO:0090314; GO:0051496; GO:0045944; GO:0019901; GO:0008565; GO:0043113; GO:0043088; GO:0050880; GO:0033628; GO:2001044; GO:0001726; GO:0006351; GO:0035148,"GDP-dissociation inhibitor activity; Notch signaling pathway; activation of protein kinase B activity; biomineral tissue development; blood vessel endothelial cell proliferation involved in sprouting angiogenesis; cell differentiation; cell-matrix adhesion; cellular response to fibroblast growth factor stimulus; cellular response to vascular endothelial growth factor stimulus; cytoskeleton; cytosol; integrin activation; integrin binding; integrin-mediated signaling pathway; lamellipodium; myoblast migration; negative regulation of ERK1 and ERK2 cascade; negative regulation of cell adhesion involved in substrate-bound cell migration; negative regulation of cell migration involved in sprouting angiogenesis; negative regulation of cell proliferation; negative regulation of fibroblast migration; negative regulation of focal adhesion assembly; negative regulation of protein binding; negative regulation of protein kinase activity; negative regulation of protein targeting to membrane; negative regulation of substrate adhesion-dependent cell spreading; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of Notch signaling pathway; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of endothelial cell migration; positive regulation of focal adhesion assembly; positive regulation of protein kinase B signaling cascade; positive regulation of protein targeting to membrane; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase II promoter; protein kinase binding; protein transporter activity; receptor clustering; regulation of Cdc42 GTPase activity; regulation of blood vessel size; regulation of cell adhesion mediated by integrin; regulation of integrin-mediated signaling pathway; ruffle; transcription, DNA-dependent; tube formation",PF10480;,,,2.00E-27,ruditapes_c30436,,,,,ITBP1_BOVIN,Bos taurus (Bovine),"activation of protein kinase B activity [GO:0032148]; biomineral tissue development [GO:0031214]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; myoblast migration [GO:0051451]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; Notch signaling pathway [GO:0007219]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein transport [GO:0015031]; receptor clustering [GO:0043113]; regulation of blood vessel size [GO:0050880]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of GTPase activity [GO:0043087]; regulation of integrin-mediated signaling pathway [GO:2001044]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]" comp130673_c0_seq1,857,42.9405,0.53991444,0,0,,,,,,,,,1.00E-65,CHOYP_AGAP_AGAP010490.1.1,,,,,,,,, comp130673_c0_seq2,2869,45.0331,0.62434141,135,32,,1.00E-104,Q8TDJ6,DmX-like protein 2 (Rabconnectin-3),DmX-like protein 2 (Rabconnectin-3),GO:0017137; GO:0030054; GO:0008021; GO:0030672,Rab GTPase binding; cell junction; synaptic vesicle; synaptic vesicle membrane,PF12234;PF00400;,,,,,,,,,DMXL2_HUMAN,Homo sapiens (Human), comp130679_c0_seq1,1860,37.2043,0.54716918,782,6055,,6.00E-168,Q5XI32,F-actin-capping protein subunit beta (CapZ beta),F-actin-capping protein subunit beta (CapZ beta),GO:0008290; GO:0071203; GO:0030036; GO:0051693; GO:0007010; GO:0022604; GO:0030017,F-actin capping protein complex; WASH complex; actin cytoskeleton organization; actin filament capping; cytoskeleton organization; regulation of cell morphogenesis; sarcomere,PF01115;,6.00E-143,CHOYP_CAPZB.1.1,2.00E-82,ruditapes_c8398,,,,,CAPZB_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; negative regulation of filopodium assembly [GO:0051490]; regulation of cell morphogenesis [GO:0022604]; regulation of lamellipodium assembly [GO:0010591] comp130683_c1_seq1,791,39.0645,0.96229415,22,319,,4.00E-19,Q90751,Bone morphogenetic protein 2 (BMP-2) (Fragment),Bone morphogenetic protein 2 (BMP-2) (Fragment),GO:0060317; GO:0051216; GO:0005615; GO:0040007; GO:0001503; GO:0010718,cardiac epithelial to mesenchymal transition; cartilage development; extracellular space; growth; ossification; positive regulation of epithelial to mesenchymal transition,PF00019;PF00688;,,,,,,,,,BMP2_CHICK,Gallus gallus (Chicken),BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cartilage development [GO:0051216]; growth [GO:0040007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; ossification [GO:0001503]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395] comp130696_c0_seq1,1747,38.008,1.28529454,87,750,,1.00E-68,Q5IS65,5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6),5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6),GO:0005929; GO:0016021; GO:0005886; GO:0004993; GO:0007210,cilium; integral to membrane; plasma membrane; serotonin receptor activity; serotonin receptor signaling pathway,PF00001;,,,,,,,,,5HT6R_PANTR,Pan troglodytes (Chimpanzee),cerebral cortex cell migration [GO:0021795]; positive regulation of TOR signaling [GO:0032008] comp130703_c2_seq1,379,48.0211,0.82599295,3,19,,,,,,,,,6.00E-58,CHOYP_LOC100869441.2.2,,,,,,,,, comp130707_c0_seq1,533,47.6548,0.4684227,2,0,,2.00E-08,O15018,PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2],PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2],GO:0007155; GO:0005911; GO:0005783; GO:0005576; GO:0005634,cell adhesion; cell-cell junction; endoplasmic reticulum; extracellular region; nucleus,PF00595;,,,,,,,,,PDZD2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp130707_c0_seq2,1598,46.8711,0.38848412,51,54,,4.00E-103,Q8N448,Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1),Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1),GO:0051260; GO:0008270,protein homooligomerization; zinc ion binding,PF00595;,7.00E-154,CHOYP_LNX2.1.1,,,,,,,LNX2_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260] comp130707_c0_seq3,590,46.4407,0.44857814,0,0,,2.00E-16,Q5PYH5,Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B),Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B),GO:0007015; GO:0016323; GO:0016337; GO:0030866; GO:0001935; GO:0045930; GO:0019902; GO:0019901; GO:0050808; GO:0007268,actin filament organization; basolateral plasma membrane; cell-cell adhesion; cortical actin cytoskeleton organization; endothelial cell proliferation; negative regulation of mitotic cell cycle; phosphatase binding; protein kinase binding; synapse organization; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,4.00E-19,CHOYP_LNX2.1.1,,,,,,,DLG1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament organization [GO:0007015]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; single organismal cell-cell adhesion [GO:0016337]; synapse organization [GO:0050808] comp130711_c0_seq1,922,45.5531,0.46250965,0,0,,3.00E-21,Q70PP2,Serine/threonine-protein kinase Smg1 (EC 2.7.11.1),Serine/threonine-protein kinase Smg1 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0046872; GO:0007274; GO:0000184; GO:0005634; GO:0018105; GO:0046777; GO:0004674; GO:0006950; GO:0050808; GO:0048489,"ATP binding; cytoplasm; metal ion binding; neuromuscular synaptic transmission; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity; response to stress; synapse organization; synaptic vesicle transport",PF02260;PF00454;PF15785;,,,,,,,,,SMG1_DROME,Drosophila melanogaster (Fruit fly),"DNA repair [GO:0006281]; neuromuscular synaptic transmission [GO:0007274]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; response to stress [GO:0006950]; synapse organization [GO:0050808]; synaptic vesicle transport [GO:0048489]" comp130711_c0_seq2,1189,46.4256,0.42258553,15,9,,0,Q9JLN9,Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),GO:0005524; GO:0000139; GO:0016605; GO:0001030; GO:0001031; GO:0001032; GO:0031929; GO:0031931; GO:0031932; GO:0071456; GO:0031669; GO:0005829; GO:0008144; GO:0005789; GO:0007281; GO:0005764; GO:0070438; GO:0005741; GO:0051534; GO:0045792; GO:0016242; GO:0005634; GO:0018105; GO:0018107; GO:0030838; GO:0001938; GO:0010592; GO:0046889; GO:0010831; GO:0050731; GO:0051897; GO:0051496; GO:0045945; GO:0045727; GO:0046777; GO:0004674; GO:0032314; GO:0043610; GO:0031998; GO:0005979; GO:0045859; GO:0032095; GO:0043200; GO:0032868; GO:0043022; GO:0031529,ATP binding; Golgi membrane; PML body; RNA polymerase III type 1 promoter DNA binding; RNA polymerase III type 2 promoter DNA binding; RNA polymerase III type 3 promoter DNA binding; TOR signaling cascade; TORC1 complex; TORC2 complex; cellular response to hypoxia; cellular response to nutrient levels; cytosol; drug binding; endoplasmic reticulum membrane; germ cell development; lysosome; mTOR-FKBP12-rapamycin complex; mitochondrial outer membrane; negative regulation of NFAT protein import into nucleus; negative regulation of cell size; negative regulation of macroautophagy; nucleus; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; positive regulation of lamellipodium assembly; positive regulation of lipid biosynthetic process; positive regulation of myotube differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase III promoter; positive regulation of translation; protein autophosphorylation; protein serine/threonine kinase activity; regulation of Rac GTPase activity; regulation of carbohydrate utilization; regulation of fatty acid beta-oxidation; regulation of glycogen biosynthetic process; regulation of protein kinase activity; regulation of response to food; response to amino acid stimulus; response to insulin stimulus; ribosome binding; ruffle organization,PF11865;PF02259;PF02260;PF00454;PF08771;,0,CHOYP_MTOR.2.2,,,,,,,MTOR_MOUSE,Mus musculus (Mouse),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] comp130727_c1_seq1,409,36.1858,0.15312883,11,49,,,,,,,,,3.00E-11,CHOYP_PARP14.14.22,,,,,,,,, comp130727_c1_seq2,495,44.0404,0.58451417,11,28,,1.00E-26,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130727_c1_seq3,427,44.9649,0.65194569,5,7,,4.00E-30,Q460N3,Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),GO:0003950; GO:0005634; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR15_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130728_c0_seq2,932,43.2403,0.85211887,0,3,,1.00E-21,Q6PKH6,Dehydrogenase/reductase SDR family member 4-like 2 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 4-like 2 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 25C member 3),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF00106;,,,,,,,,,DR4L2_HUMAN,Homo sapiens (Human), comp130728_c0_seq5,996,43.2731,0.79660182,6,4,,5.00E-39,Q9WYG0,Uncharacterized oxidoreductase TM_0325 (EC 1.-.-.-),Uncharacterized oxidoreductase TM_0325 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,,,,,,,,,,Y325_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099), comp130735_c1_seq2,893,46.9205,1.06020932,34,101,,,,,,,,,,,2.00E-74,ruditapes_c17896,,,,,,, comp130737_c0_seq1,1860,38.6022,0.59387008,148,131,,0,Q6UW63,KDEL motif-containing protein 1 (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58),KDEL motif-containing protein 1 (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58),GO:0005788,endoplasmic reticulum lumen,PF00630;PF05686;,8.00E-46,CHOYP_KDEL1.1.1,4.00E-60,ruditapes_c24494,,,,,KDEL1_HUMAN,Homo sapiens (Human),glycolipid metabolic process [GO:0006664] comp130739_c1_seq1,1300,41.1538,0.58802295,31,128,,3.00E-76,Q9WV76,AP-4 complex subunit beta-1 (AP-4 adapter complex subunit beta) (Adapter-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin),AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin),GO:0005794; GO:0030131; GO:0006886; GO:0008565; GO:0005802; GO:0016192,Golgi apparatus; clathrin adaptor complex; intracellular protein transport; protein transporter activity; trans-Golgi network; vesicle-mediated transport,PF01602;PF09066;,,,,,,,,,AP4B1_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp130747_c0_seq2,432,41.4352,0.66157727,0,1,,,,,,,,,,,2.00E-32,ruditapes_c27470,,,,,,, comp130747_c1_seq1,853,43.3763,0.60524534,36,131,,2.00E-60,Q9W6S3,Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1),Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1),GO:0005794; GO:0046580; GO:0070300; GO:0005547; GO:0043325; GO:0080025; GO:0005546; GO:0005886,"Golgi apparatus; negative regulation of Ras protein signal transduction; phosphatidic acid binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane",PF16978;PF05422;PF16979;,,,,,,,,,SIN1_CHICK,Gallus gallus (Chicken),negative regulation of Ras protein signal transduction [GO:0046580]; substantia nigra development [GO:0021762] comp130747_c2_seq1,529,47.448,0.37030112,2,6,,3.00E-29,Q9V719,Stress-activated map kinase-interacting protein 1 (SAPK-interacting protein 1) (dSin1),Stress-activated map kinase-interacting protein 1 (SAPK-interacting protein 1) (dSin1),GO:0006915; GO:0048813; GO:0001932; GO:0051124,apoptotic process; dendrite morphogenesis; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF16978;PF05422;PF16979;,,,,,,,,,SIN1_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; dendrite morphogenesis [GO:0048813]; regulation of protein phosphorylation [GO:0001932]; synaptic growth at neuromuscular junction [GO:0051124] comp130747_c2_seq2,526,46.3878,0.35428699,0,0,,3.00E-12,Q9NA80,Stress-activated map kinase-interacting protein 1 homolog,Stress-activated map kinase-interacting protein 1 homolog,GO:0006950,response to stress,PF16978;,1.00E-44,CHOYP_SIN1.1.1,,,,,,,SIN1_CAEEL,Caenorhabditis elegans,mesendoderm development [GO:0048382] comp130748_c2_seq2,2105,42.6603,0.27290676,49,17,,5.00E-12,Q8N2E2,von Willebrand factor D and EGF domain-containing protein,von Willebrand factor D and EGF domain-containing protein,GO:0005576,extracellular region,PF12661;PF00094;,,,,,,,,,VWDE_HUMAN,Homo sapiens (Human), comp130748_c3_seq2,1171,42.0154,0.29080945,17,7,,2.00E-17,Q8N2E2,von Willebrand factor D and EGF domain-containing protein,von Willebrand factor D and EGF domain-containing protein,GO:0005576,extracellular region,PF12661;PF00094;,,,,,,,,,VWDE_HUMAN,Homo sapiens (Human), comp130749_c0_seq3,1025,45.0732,0.35679406,6,0,,4.00E-49,A7MBH5,Coiled-coil domain-containing protein 151,Coiled-coil domain-containing protein 151,,,,0,CHOYP_LOC100367974.1.3,,,,,,,CC151_BOVIN,Bos taurus (Bovine),cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; outer dynein arm assembly [GO:0036158]; regulation of cilium assembly [GO:1902017] comp130751_c0_seq1,1110,41.1712,0.27710011,120,35,,1.00E-52,Q9NDH7,"Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase (EC 2.4.1.155) (GlcNAc-TV) (Glycosylation-related protein 2) (N-acetylglucosaminyltransferase gly-2)","Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase (EC 2.4.1.155) (GlcNAc-TV) (Glycosylation-related protein 2) (N-acetylglucosaminyltransferase gly-2)",GO:0000139; GO:0005795; GO:0030144; GO:0016021; GO:0046872; GO:0005634; GO:0006487; GO:0016758,"Golgi membrane; Golgi stack; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; integral to membrane; metal ion binding; nucleus; protein N-linked glycosylation; transferase activity, transferring hexosyl groups",,,,,,,,,,GLY2_CAEEL,Caenorhabditis elegans,protein N-linked glycosylation [GO:0006487] comp130751_c0_seq3,1467,41.9905,0.29647123,135,77,,5.00E-127,P97259,"Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V)","Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V)",GO:0000139; GO:0030144; GO:0016021; GO:0006487,"Golgi membrane; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; integral to membrane; protein N-linked glycosylation",PF15027;,3.00E-100,CHOYP_MGT5A.1.1,,,,,,,MGT5A_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),protein N-linked glycosylation [GO:0006487] comp130752_c0_seq1,1041,39.8655,0.98172316,28,106,,2.00E-16,P05366,Serum amyloid A-1 protein,Serum amyloid A-1 protein,GO:0006953; GO:0008203; GO:0005615; GO:0034364,acute-phase response; cholesterol metabolic process; extracellular space; high-density lipoprotein particle,PF00277;,4.00E-15,CHOYP_BRAFLDRAFT_124064.5.6,,,,,,,SAA1_MOUSE,Mus musculus (Mouse),acute-phase response [GO:0006953]; cell chemotaxis [GO:0060326]; cholesterol metabolic process [GO:0008203] comp130752_c0_seq3,851,38.4254,0.87169503,19,157,,3.00E-23,P35542,Serum amyloid A-4 protein (Constitutively expressed serum amyloid A protein) (C-SAA),Serum amyloid A-4 protein (Constitutively expressed serum amyloid A protein) (C-SAA),GO:0006953; GO:0005576; GO:0034364,acute-phase response; extracellular region; high-density lipoprotein particle,PF00277;,,,1.00E-11,ruditapes_lrc28818,,,,,SAA4_HUMAN,Homo sapiens (Human),acute-phase response [GO:0006953]; cell chemotaxis [GO:0060326] comp130752_c0_seq4,545,43.6697,0.98913376,3,152,,1.00E-38,P19453,Serum amyloid A-3 protein,Serum amyloid A-3 protein,GO:0006953; GO:0034364,acute-phase response; high-density lipoprotein particle,PF00277;,7.00E-15,CHOYP_BRAFLDRAFT_124064.6.6,1.00E-16,ruditapes_lrc32288,,,,,SAA3_MESAU,Mesocricetus auratus (Golden hamster),acute-phase response [GO:0006953] comp130760_c0_seq1,1203,37.6559,0.61033382,93986,139413,,8.00E-95,Q96A72,Protein mago nashi homolog 2,Protein mago nashi homolog 2,GO:0003723; GO:0008380; GO:0006397; GO:0051028; GO:0005634,RNA binding; RNA splicing; mRNA processing; mRNA transport; nucleus,PF02792;,3.00E-112,CHOYP_MGN2.1.1,1.00E-128,ruditapes2_c3333,6.00E-111,BQ426947.p.cg.6,8,,MGN2_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA splicing [GO:0008380]" comp130764_c0_seq1,1127,38.6868,0.43493383,33,170,,3.00E-39,Q7ZTY7,Vesicle transport protein USE1 (USE1-like protein),Vesicle transport protein USE1 (USE1-like protein),GO:0005789; GO:0016021; GO:0015031; GO:0016192,endoplasmic reticulum membrane; integral to membrane; protein transport; vesicle-mediated transport,PF09753;,,,3.00E-47,ruditapes_c23836,,,,,USE1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp130768_c0_seq1,594,39.5623,1.12297066,17,144,,4.00E-08,Q05A80,Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (RNA granule protein 140),Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (RNA granule protein 140),GO:0003723; GO:0005739; GO:0030308; GO:0017148; GO:0050775; GO:0061003,RNA binding; mitochondrion; negative regulation of cell growth; negative regulation of translation; positive regulation of dendrite morphogenesis; positive regulation of dendritic spine morphogenesis,PF00386;PF12287;,,,,,,,,,CAPR2_MOUSE,Mus musculus (Mouse),negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp130772_c0_seq3,1043,39.5014,1.07500099,0,0,,2.00E-16,Q3T077,Tubulin polymerization-promoting protein family member 2,Tubulin polymerization-promoting protein family member 2,GO:0005737,cytoplasm,PF05517;,,,,,,,,,TPPP2_BOVIN,Bos taurus (Bovine), comp130773_c0_seq1,768,42.9688,0.39968883,34,104,,5.00E-51,P42173,Uncoordinated protein 79,Uncoordinated protein 79,GO:0030424; GO:0040017; GO:0042493,axon; positive regulation of locomotion; response to drug,,2.00E-62,CHOYP_UNC79.1.4,,,,,,,UNC79_CAEEL,Caenorhabditis elegans,positive regulation of locomotion [GO:0040017]; response to drug [GO:0042493] comp130777_c0_seq1,857,43.1739,0.60060082,93,215,,5.00E-53,P17130,Heterogeneous nuclear ribonucleoproteins A1 homolog (hnRNP A1) (Helix-destabilizing protein) (Single-strand-binding protein) (hnRNP core protein A1),Heterogeneous nuclear ribonucleoproteins A1 homolog (hnRNP A1) (Helix-destabilizing protein) (Single-strand-binding protein) (hnRNP core protein A1),GO:0003723; GO:0005737; GO:0000166; GO:0005634; GO:0030529,RNA binding; cytoplasm; nucleotide binding; nucleus; ribonucleoprotein complex,PF00076;,,,,,,,,,ROA1_XENLA,Xenopus laevis (African clawed frog), comp130777_c0_seq2,866,43.1871,0.6000008,82,228,,4.00E-55,P07909,Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),GO:0036099; GO:0048027; GO:0033119; GO:0000166; GO:0005634; GO:0048477; GO:0005703; GO:0045727; GO:0000381; GO:0030529; GO:0043565,"female germ-line stem cell maintenance; mRNA 5'-UTR binding; negative regulation of RNA splicing; nucleotide binding; nucleus; oogenesis; polytene chromosome puff; positive regulation of translation; regulation of alternative mRNA splicing, via spliceosome; ribonucleoprotein complex; sequence-specific DNA binding",PF00076;,,,,,,,,,ROA1_DROME,Drosophila melanogaster (Fruit fly),"compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]" comp130779_c0_seq1,570,40.8772,0.59701453,26,83,,2.00E-61,Q9JKB8,Pre-mRNA-splicing factor 18 (PRP18 homolog) (Potassium channel regulatory factor),Pre-mRNA-splicing factor 18 (PRP18 homolog) (Potassium channel regulatory factor),GO:0008380; GO:0006397; GO:0016607; GO:0019870; GO:0005681,RNA splicing; mRNA processing; nuclear speck; potassium channel inhibitor activity; spliceosomal complex,PF02840;PF08799;,3.00E-45,CHOYP_PRP18.1.1,,,,,,,PRP18_RAT,Rattus norvegicus (Rat),generation of catalytic spliceosome for second transesterification step [GO:0000350]; negative regulation of cellular protein metabolic process [GO:0032269]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048] comp130787_c0_seq2,780,39.2308,0.56804954,35,67,,2.00E-28,Q8BQN6,Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146),Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146),GO:0003677; GO:0005737; GO:0046872; GO:0005730,DNA binding; cytoplasm; metal ion binding; nucleolus,PF00096;,,,,,,,,,OZF_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp130788_c0_seq1,668,41.6168,0.25685665,12,337,,1.00E-29,Q3MHP8,BET1-like protein,BET1-like protein,GO:0000139; GO:0005795; GO:0005768; GO:0016021; GO:0005634; GO:0015031; GO:0042147,"Golgi membrane; Golgi stack; endosome; integral to membrane; nucleus; protein transport; retrograde transport, endosome to Golgi",,,,,,,,,,BET1L_BOVIN,Bos taurus (Bovine),"membrane fusion [GO:0061025]; protein transport [GO:0015031]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; retrograde transport, endosome to Golgi [GO:0042147]" comp130790_c0_seq1,1446,40.3181,0.56903359,63,0,,,,,,,,,8.00E-127,CHOYP_LOC100370516.1.1,,,,,,,,, comp130790_c0_seq2,1446,40.0415,0.48019934,266,48,,0,Q6PFJ9,E3 ubiquitin-protein ligase arih1 (EC 6.3.2.-) (Protein ariadne-1 homolog) (ARI-1),E3 ubiquitin-protein ligase arih1 (EC 6.3.2.-) (Protein ariadne-1 homolog) (ARI-1),GO:0005737; GO:0004842; GO:0008270,cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF01485;,0,CHOYP_LOC100370516.1.1,,,7.00E-130,AM862765.p.cg.6,5,male gonad,ARI1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp130795_c0_seq1,1039,41.6747,0.44416014,29,0,,,,,,,,,6.00E-13,CHOYP_LOC100372601.1.1,,,,,,,,, comp130795_c0_seq5,613,41.925,0.4104289,9,0,,6.00E-53,Q8C7W7,5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B),5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B),GO:0008409; GO:0000075; GO:0005813; GO:0000781; GO:0005737; GO:0006289; GO:0005634; GO:0031848; GO:0031860; GO:0031627,"5'-3' exonuclease activity; cell cycle checkpoint; centrosome; chromosome, telomeric region; cytoplasm; nucleotide-excision repair; nucleus; protection from non-homologous end joining at telomere; telomeric 3' overhang formation; telomeric loop formation",PF07522;,4.00E-13,CHOYP_LOC100372601.1.1,,,,,,,DCR1B_MOUSE,Mus musculus (Mouse),cell cycle checkpoint [GO:0000075]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289]; protection from non-homologous end joining at telomere [GO:0031848]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627] comp130795_c1_seq2,2059,35.8426,0.38091725,1,0,,8.00E-12,B0V2S2,5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B),5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B),GO:0008409; GO:0006281; GO:0000075; GO:0005813; GO:0000781; GO:0005634; GO:0031848; GO:0031860; GO:0031627,"5'-3' exonuclease activity; DNA repair; cell cycle checkpoint; centrosome; chromosome, telomeric region; nucleus; protection from non-homologous end joining at telomere; telomeric 3' overhang formation; telomeric loop formation",PF07522;PF12706;,,,,,,,,,DCR1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle checkpoint [GO:0000075]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627] comp130800_c0_seq1,810,36.1728,0.6869011,366,1927,,,,,,,,,,,6.00E-35,ruditapes_c20627,,,,,,, comp130802_c0_seq1,2509,44.7589,0.52417679,195,103,,0,O15050,TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),GO:0005524; GO:0016787,ATP binding; hydrolase activity,PF00580;,2.00E-151,CHOYP_TRNK1.4.6,,,,,,,TRNK1_HUMAN,Homo sapiens (Human), comp130803_c0_seq1,265,46.4151,0.42222823,9557,81492,,5.00E-56,P23398,Polyubiquitin [Cleaved into: Ubiquitin] (Fragment),Polyubiquitin [Cleaved into: Ubiquitin] (Fragment),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00240;,2.00E-82,CHOYP_LOC100190730.2.2,6.00E-86,ruditapes2_lrc2999,,,,,UBIQP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp130803_c0_seq4,202,47.5248,0.52888834,5689,45104,,3.00E-40,P23398,Polyubiquitin [Cleaved into: Ubiquitin] (Fragment),Polyubiquitin [Cleaved into: Ubiquitin] (Fragment),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00240;,,,1.00E-41,ruditapes2_c1404,,,,,UBIQP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp130809_c0_seq1,2222,46.0396,0.40784946,73,9,,6.00E-60,Q8TDY8,Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36),Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00041;PF07679;,,,,,,,,,IGDC4_HUMAN,Homo sapiens (Human), comp130809_c0_seq2,1229,44.9146,0.3552722,2,0,,4.00E-08,H2A0L8,Fibronectin type III domain-containing protein 2,Fibronectin type III domain-containing protein 2,GO:0005576,extracellular region,PF00041;,,,,,,,,,FND2_PINMG,Pinctada margaritifera (Black-lipped pearl oyster), comp130809_c0_seq4,479,46.9729,0.38016956,26,0,,5.00E-08,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp130811_c0_seq1,1734,37.4856,0.28717065,936,4376,,3.00E-137,Q9UJZ1,"Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)","Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)",GO:0035710; GO:0050852; GO:1901612; GO:0006874; GO:0005856; GO:0019897; GO:0032623; GO:0010876; GO:0045121; GO:0042776; GO:0006851; GO:0005743; GO:0005758; GO:0034982; GO:1900210; GO:0090297; GO:0010918; GO:0051259; GO:0005102; GO:1990046,"CD4-positive, alpha-beta T cell activation; T cell receptor signaling pathway; cardiolipin binding; cellular calcium ion homeostasis; cytoskeleton; extrinsic to plasma membrane; interleukin-2 production; lipid localization; membrane raft; mitochondrial ATP synthesis coupled proton transport; mitochondrial calcium ion transport; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial protein processing; positive regulation of cardiolipin metabolic process; positive regulation of mitochondrial DNA replication; positive regulation of mitochondrial membrane potential; protein oligomerization; receptor binding; stress-induced mitochondrial fusion",PF01145;PF16200;,8.00E-71,CHOYP_LOC100169460.1.1,2.00E-153,ruditapes2_c2816,,,,,STML2_HUMAN,Homo sapiens (Human),"CD4-positive, alpha-beta T cell activation [GO:0035710]; cellular calcium ion homeostasis [GO:0006874]; interleukin-2 production [GO:0032623]; lipid localization [GO:0010876]; mitochondrial ATP synthesis coupled proton transport [GO:0042776]; mitochondrial calcium ion transport [GO:0006851]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; positive regulation of cardiolipin metabolic process [GO:1900210]; positive regulation of mitochondrial DNA replication [GO:0090297]; positive regulation of mitochondrial membrane potential [GO:0010918]; protein oligomerization [GO:0051259]; stress-induced mitochondrial fusion [GO:1990046]; T cell receptor signaling pathway [GO:0050852]" comp130818_c0_seq1,893,43.1131,0.60707377,10,36,,1.00E-11,P37278,Probable calcium-transporting ATPase (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0005886,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; plasma membrane,PF00689;PF00690;PF00122;,4.00E-103,CHOYP_ATP7A.1.1,,,,,,,ATCL_SYNE7,Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2), comp130818_c1_seq1,1088,48.0699,0.42228224,6,6,,2.00E-131,Q64430,Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog),Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog),GO:0005524; GO:0042093; GO:0001568; GO:0001974; GO:0051216; GO:0006878; GO:0021702; GO:0030199; GO:0015677; GO:0004008; GO:0048813; GO:0010273; GO:0042417; GO:0048251; GO:0051542; GO:0042414; GO:0031069; GO:0016021; GO:0007626; GO:0048286; GO:0048553; GO:0043524; GO:0043005; GO:0043025; GO:0042421; GO:0018205; GO:0043473; GO:0005886; GO:0048554; GO:0021860; GO:0010468; GO:0002082; GO:0001836; GO:0019430; GO:0042428; GO:0016532; GO:0005802; GO:0030140; GO:0006568; GO:0006570,ATP binding; T-helper cell differentiation; blood vessel development; blood vessel remodeling; cartilage development; cellular copper ion homeostasis; cerebellar Purkinje cell differentiation; collagen fibril organization; copper ion import; copper-exporting ATPase activity; dendrite morphogenesis; detoxification of copper ion; dopamine metabolic process; elastic fiber assembly; elastin biosynthetic process; epinephrine metabolic process; hair follicle morphogenesis; integral to membrane; locomotory behavior; lung alveolus development; negative regulation of metalloenzyme activity; negative regulation of neuron apoptotic process; neuron projection; neuronal cell body; norepinephrine biosynthetic process; peptidyl-lysine modification; pigmentation; plasma membrane; positive regulation of metalloenzyme activity; pyramidal neuron development; regulation of gene expression; regulation of oxidative phosphorylation; release of cytochrome c from mitochondria; removal of superoxide radicals; serotonin metabolic process; superoxide dismutase copper chaperone activity; trans-Golgi network; trans-Golgi network transport vesicle; tryptophan metabolic process; tyrosine metabolic process,PF00122;PF00403;,,,,,,,,,ATP7A_MOUSE,Mus musculus (Mouse),ATP metabolic process [GO:0046034]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of neuron apoptotic process [GO:0043524]; neuron projection morphogenesis [GO:0048812]; norepinephrine biosynthetic process [GO:0042421]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of oxidoreductase activity [GO:0051353]; pyramidal neuron development [GO:0021860]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]; tyrosine metabolic process [GO:0006570] comp130818_c1_seq2,996,47.7912,0.44620525,0,0,,2.00E-30,P0A502,Probable manganese/zinc-exporting P-type ATPase (EC 3.6.3.-) (Cation-transporting P-type ATPase CtpC) (Metal-transporting ATPase Mta72),,GO:0005524; GO:0019829; GO:0005576; GO:0016021; GO:0046872; GO:0005886,ATP binding; cation-transporting ATPase activity; extracellular region; integral to membrane; metal ion binding; plasma membrane,,,,,,,,,,CTPC_MYCTU,, comp130823_c0_seq1,1380,43.0435,0.34774764,61,158,,0,Q5ZJL4,Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1),Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1),GO:0005524; GO:0046404; GO:0051736; GO:0006397; GO:0051733; GO:0035087; GO:0006388; GO:0000214; GO:0030423,"ATP binding; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; mRNA processing; polydeoxyribonucleotide kinase activity; siRNA loading onto RISC involved in RNA interference; tRNA splicing, via endonucleolytic cleavage and ligation; tRNA-intron endonuclease complex; targeting of mRNA for destruction involved in RNA interference",PF06807;PF16573;PF16575;,1.00E-87,CHOYP_CLP1.1.1,2.00E-18,ruditapes_c21442,,,,,CLP1_CHICK,Gallus gallus (Chicken),"cerebellar cortex development [GO:0021695]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp130830_c0_seq1,1421,44.0535,0.46907495,131,1082,,0,Q4QQY7,Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase),Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase),GO:0046872; GO:0008479; GO:0008616,metal ion binding; queuine tRNA-ribosyltransferase activity; queuosine biosynthetic process,PF01702;,1.00E-175,CHOYP_LOC100367470.1.1,1.00E-27,ruditapes_c18838,,,,,TGT_XENLA,Xenopus laevis (African clawed frog),queuosine biosynthetic process [GO:0008616]; tRNA modification [GO:0006400] comp130834_c0_seq1,1170,28.2051,0.82707023,8,98,,,,,,,,,,,4.00E-13,ruditapes_c27413,,,,,,, comp130839_c1_seq1,1065,41.0329,0.25947093,7,23,,1.00E-14,Q96ES6,Major facilitator superfamily domain-containing protein 3,Major facilitator superfamily domain-containing protein 3,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,MFSD3_HUMAN,Homo sapiens (Human), comp130839_c1_seq2,905,40,0.26378138,2,18,,3.00E-25,Q4V8E5,Major facilitator superfamily domain-containing protein 3,Major facilitator superfamily domain-containing protein 3,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,MFSD3_RAT,Rattus norvegicus (Rat), comp130846_c0_seq1,2064,40.407,0.70074903,4639,23228,,2.00E-20,Q3SZZ2,X-box-binding protein 1 (XBP-1),"X-box-binding protein 1 (XBP-1) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]",GO:0060691; GO:0031017; GO:0005634; GO:1900103; GO:0043565; GO:0003700; GO:0006351,"epithelial cell maturation involved in salivary gland development; exocrine pancreas development; nucleus; positive regulation of endoplasmic reticulum unfolded protein response; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF07716;,1.00E-12,CHOYP_XBP1.4.4,1.00E-48,ruditapes_c13005,,,,,XBP1_BOVIN,Bos taurus (Bovine),adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to oxidative stress [GO:0034599]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of histone methylation [GO:0031062]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; sterol homeostasis [GO:0055092]; transcription from RNA polymerase II promoter [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp130849_c0_seq1,988,42.8138,1.08532347,2,23,,1.00E-78,Q8NEX9,Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S),Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S),GO:0005737; GO:0005730; GO:0004745,cytoplasm; nucleolus; retinol dehydrogenase activity,PF00106;,,,,,,,,,DR9C7_HUMAN,Homo sapiens (Human),oxidation-reduction process [GO:0055114] comp130849_c0_seq3,1007,42.8997,1.08090707,0,6,,2.00E-69,O55240,11-cis retinol dehydrogenase (11-cis RDH) (11-cis RoDH) (EC 1.1.1.315) (9-cis retinol dehydrogenase) (Cis-retinol dehydrogenase) (Retinol dehydrogenase 5),11-cis retinol dehydrogenase (11-cis RDH) (11-cis RoDH) (EC 1.1.1.315) (9-cis retinol dehydrogenase) (Cis-retinol dehydrogenase) (Retinol dehydrogenase 5),GO:0005788; GO:0016020; GO:0016491; GO:0050896; GO:0042572; GO:0007601,endoplasmic reticulum lumen; membrane; oxidoreductase activity; response to stimulus; retinol metabolic process; visual perception,PF00106;,,,,,,,,,RDH1_MOUSE,Mus musculus (Mouse),response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] comp130850_c0_seq1,1203,38.9859,0.62224562,948,2528,,1.00E-41,Q9VMY1,"Probable 39S ribosomal protein L24, mitochondrial (L24mt) (MRP-L24)","Probable 39S ribosomal protein L24, mitochondrial (L24mt) (MRP-L24)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF00467;PF17136;,,,2.00E-12,ruditapes_c314,,,,,RM24_DROME,Drosophila melanogaster (Fruit fly),sensory perception of pain [GO:0019233]; translation [GO:0006412] comp130851_c0_seq1,1965,39.084,0.40633278,551,4951,,1.00E-52,Q5ZKQ3,RNA polymerase II-associated protein 3,RNA polymerase II-associated protein 3,,,PF13877;PF00515;PF13176;,6.00E-35,CHOYP_LOC577383.1.1,,,,,,,RPAP3_CHICK,Gallus gallus (Chicken), comp130853_c0_seq1,645,43.2558,0.46690871,332,411,,1.00E-14,Q7VWE9,Probable transcriptional regulatory protein BP2308,Probable transcriptional regulatory protein BP2308,GO:0003677; GO:0005737; GO:0006355; GO:0006351,"DNA binding; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01709;,,,,,,,,,Y2308_BORPE,Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130853_c1_seq1,721,33.4258,0.40211718,443,473,,3.00E-14,Q9BSH4,Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase I),Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase I),GO:0005739; GO:0006417,mitochondrion; regulation of translation,PF01709;,,,,,,,,,TACO1_HUMAN,Homo sapiens (Human),regulation of translation [GO:0006417] comp130854_c0_seq1,778,37.018,0.60343842,25,207,,3.00E-70,Q8C460,ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein),ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein),GO:0004527; GO:0046872; GO:0003676; GO:0090305; GO:0005886,exonuclease activity; metal ion binding; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; plasma membrane,PF00929;,8.00E-29,CHOYP_ERI3.1.2,3.00E-44,ruditapes_c12653,,,,,ERI3_MOUSE,Mus musculus (Mouse),"exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]" comp130855_c0_seq1,1180,43.5593,0.43357381,12,255,,3.00E-43,Q13625,Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2),Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2),GO:0005070; GO:0007049; GO:0007417; GO:0005737; GO:0009792; GO:0007507; GO:0072332; GO:0045786; GO:0005634; GO:0048471; GO:0010212,SH3/SH2 adaptor activity; cell cycle; central nervous system development; cytoplasm; embryo development ending in birth or egg hatching; heart development; intrinsic apoptotic signaling pathway by p53 class mediator; negative regulation of cell cycle; nucleus; perinuclear region of cytoplasm; response to ionizing radiation,PF12796;PF00018;,,,,,,,,,ASPP2_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell cycle [GO:0045786]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of apoptotic process [GO:0042981]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165] comp130863_c2_seq1,869,33.7169,1.30667591,18,100,,,,,,,,,,,5.00E-30,ruditapes_c25123,,,,,,, comp130867_c1_seq1,1506,41.6999,0.30258819,19,39,,9.00E-16,Q91VW5,Golgin subfamily A member 4 (tGolgin-1),Golgin subfamily A member 4 (tGolgin-1),GO:0005794; GO:0000139; GO:0043001; GO:0000042,Golgi apparatus; Golgi membrane; Golgi to plasma membrane protein transport; protein targeting to Golgi,PF01465;,,,,,,,,,GOGA4_MOUSE,Mus musculus (Mouse),Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; protein targeting to Golgi [GO:0000042] comp130870_c0_seq1,1601,39.2255,0.9588828,0,110,,2.00E-64,Q7LFX5,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0030206; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; chondroitin sulfate biosynthetic process; hexose biosynthetic process; integral to membrane,,,,,,,,,,CHSTF_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319] comp130872_c0_seq1,615,31.0569,0.27053212,15,41,,4.00E-09,P10401,Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00665;PF00078;,,,,,,,,,POLY_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp130873_c0_seq2,2023,44.439,0.44095871,0,0,,7.00E-177,Q96RV3,Pecanex-like protein 1 (Pecanex homolog),Pecanex-like protein 1 (Pecanex homolog protein 1),GO:0016021,integral to membrane,PF05041;,,,,,,,,,PCX1_HUMAN,Homo sapiens (Human), comp130873_c0_seq3,768,42.9688,0.33895374,0,0,,,,,,,,,9.00E-79,CHOYP_PCX1.1.1,,,,,,,,, comp130873_c0_seq5,1975,44.4051,0.44214569,0,0,,7.00E-177,Q96RV3,Pecanex-like protein 1 (Pecanex homolog),Pecanex-like protein 1 (Pecanex homolog protein 1),GO:0016021,integral to membrane,PF05041;,,,,,,,,,PCX1_HUMAN,Homo sapiens (Human), comp130873_c0_seq6,449,43.2071,0.34091078,0,0,,,,,,,,,3.00E-25,CHOYP_PCX1.1.1,,,,,,,,, comp130877_c3_seq2,1351,49.2228,0.48919068,0,12,,,,,,,,,5.00E-53,CHOYP_LOC593558.2.4,,,,,,,,, comp13087_c0_seq1,221,41.629,0.70440363,4,0,,3.00E-17,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp130881_c0_seq2,1521,37.0809,0.53632039,655,237,,1.00E-16,A8MTL3,RING finger protein C14orf164,RING finger protein 212B,GO:0008270,zinc ion binding,,,,,,,,,,CN164_HUMAN,Homo sapiens (Human), comp130882_c0_seq2,1039,44.5621,0.54448276,2,0,,3.00E-60,Q8IYW2,Tetratricopeptide repeat protein 40,Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40),,,,1.00E-122,CHOYP_LOC100374785.1.3,,,,,,,TTC40_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294] comp130883_c0_seq1,894,36.2416,0.41435237,90,64,,1.00E-21,C3KJF2,DNA repair protein SWI5 homolog (Protein SAE3 homolog),DNA repair protein SWI5 homolog (Protein SAE3 homolog),GO:0032798; GO:0000724,Swi5-Sfr1 complex; double-strand break repair via homologous recombination,PF07061;,,,,,,,,,SWI5_ANOFI,Anoplopoma fimbria (Sablefish),double-strand break repair via homologous recombination [GO:0000724] comp130884_c0_seq1,1037,38.9585,0.5856069,84,735,,7.00E-47,Q03111,Protein ENL (YEATS domain-containing protein 1),Protein ENL (YEATS domain-containing protein 1),GO:0003677; GO:0005737; GO:0006469; GO:0005730; GO:0006355; GO:0006366,"DNA binding; cytoplasm; negative regulation of protein kinase activity; nucleolus; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF03366;,2.00E-26,CHOYP_ENL.1.1,3.00E-21,ruditapes2_c2301,,,,,ENL_HUMAN,Homo sapiens (Human),"negative regulation of protein kinase activity [GO:0006469]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp130887_c0_seq1,699,42.6323,0.60794566,44,56,,2.00E-59,Q9CR00,26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27),26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27),GO:0043425; GO:0046676; GO:0005634; GO:0032024; GO:0045893; GO:0070682; GO:0003713,"bHLH transcription factor binding; negative regulation of insulin secretion; nucleus; positive regulation of insulin secretion; positive regulation of transcription, DNA-dependent; proteasome regulatory particle assembly; transcription coactivator activity",PF13180;,,,,,,,,,PSMD9_MOUSE,Mus musculus (Mouse),"negative regulation of insulin secretion [GO:0046676]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasome regulatory particle assembly [GO:0070682]" comp130889_c0_seq1,1017,47.591,0.50998529,6,4,,3.00E-125,Q14527,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),GO:0005524; GO:0016887; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005654; GO:0005634; GO:0016567; GO:0006357; GO:0006355; GO:0006351; GO:0008270,"ATP binding; ATPase activity; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleoplasm; nucleus; protein ubiquitination; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,2.00E-88,CHOYP_HLTF.1.1,,,,,,,HLTF_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription, DNA-templated [GO:0006355]" comp130889_c0_seq2,992,46.4718,0.48786898,1,10,,2.00E-106,Q14527,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),GO:0005524; GO:0016887; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005654; GO:0005634; GO:0016567; GO:0006357; GO:0006355; GO:0006351; GO:0008270,"ATP binding; ATPase activity; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleoplasm; nucleus; protein ubiquitination; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,,,,,,,,,HLTF_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription, DNA-templated [GO:0006355]" comp130890_c1_seq2,1583,49.3999,0.6632127,0,0,,3.00E-33,Q8K4B0,Metastasis-associated protein MTA1,Metastasis-associated protein MTA1,GO:0016581; GO:0003682; GO:0005737; GO:0043565; GO:0003700; GO:0008270,NuRD complex; chromatin binding; cytoplasm; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF01426;PF01448;PF00320;PF00249;,,,,,,,,,MTA1_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]" comp130890_c1_seq4,973,49.7431,0.70433959,0,0,,3.00E-35,Q9BTC8,Metastasis-associated protein MTA3,Metastasis-associated protein MTA3,GO:0016581; GO:0003682; GO:0008278; GO:0005737; GO:0005634; GO:0010971; GO:0008284; GO:0043565; GO:0003700; GO:0008270,NuRD complex; chromatin binding; cohesin complex; cytoplasm; nucleus; positive regulation of G2/M transition of mitotic cell cycle; positive regulation of cell proliferation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF01426;PF01448;PF00320;,,,,,,,,,MTA3_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]" comp130890_c1_seq6,1697,49.2634,0.65125274,0,0,,1.00E-115,Q62901,Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-related protein),Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-related protein),GO:0016605; GO:0003682; GO:0006338; GO:0000118; GO:0005739; GO:0007275; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"PML body; chromatin binding; chromatin remodeling; histone deacetylase complex; mitochondrion; multicellular organismal development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF03154;PF01426;PF01448;PF00320;,,,,,,,,,RERE_RAT,Rattus norvegicus (Rat),branching morphogenesis of a nerve [GO:0048755]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell layer maturation [GO:0021691]; chromatin remodeling [GO:0006338]; dendrite morphogenesis [GO:0048813]; radial glia guided migration of Purkinje cell [GO:0021942] comp130890_c1_seq7,553,50.0904,0.79904107,0,0,,3.00E-08,Q3U3N0,Mesoderm induction early response protein 2 (Mi-er2),Mesoderm induction early response protein 2 (Mi-er2),GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01448;,1.00E-63,CHOYP_CARNS1.5.6,,,,,,,MIER2_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130890_c1_seq8,859,50.0582,0.73257132,0,0,,1.00E-07,Q8N344,Mesoderm induction early response protein 2 (Mi-er2),Mesoderm induction early response protein 2 (Mi-er2),GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01448;,8.00E-74,CHOYP_CARNS1.5.6,,,,,,,MIER2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp130892_c0_seq1,2065,40.4358,0.43865639,36,19,,5.00E-180,Q3SZH6,Probable tubulin polyglutamylase TTLL9 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 9),Probable tubulin polyglutamylase TTLL9 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 9),GO:0006464; GO:0005929; GO:0005737; GO:0016874; GO:0005874; GO:0005932,cellular protein modification process; cilium; cytoplasm; ligase activity; microtubule; microtubule basal body,PF03133;,,,,,,,,,TTLL9_BOVIN,Bos taurus (Bovine),cellular protein modification process [GO:0006464] comp130892_c0_seq2,1874,41.4088,0.46119955,0,0,,1.00E-97,Q23SI8,Probable alpha-tubulin polyglutamylase Ttll1 (EC 6.-.-.-) (Tubulin-tyrosine ligase family protein 1),Probable alpha-tubulin polyglutamylase Ttll1 (EC 6.-.-.-) (Tubulin-tyrosine ligase family protein 1),GO:0005929; GO:0000331; GO:0005874; GO:0005932; GO:0018095; GO:0070740,cilium; contractile vacuole; microtubule; microtubule basal body; protein polyglutamylation; tubulin-glutamic acid ligase activity,PF03133;,0,CHOYP_LOC100634892.2.2,,,3.00E-65,FP008556.p.cg.6,6,,TTLL1_TETTS,Tetrahymena thermophila (strain SB210),protein polyglutamylation [GO:0018095] comp130895_c1_seq2,823,36.3305,0.18508563,0,3,,1.00E-12,Q5U1Z0,Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0030234; GO:0005886; GO:0043547,GTPase activator activity; cytoplasm; enzyme regulator activity; plasma membrane; positive regulation of GTPase activity,PF14656;PF14655;,,,,,,,,,RBGPR_RAT,Rattus norvegicus (Rat),positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp130898_c0_seq1,1649,45.846,0.46274241,102,69,,5.00E-65,P78509,Reelin (EC 3.4.21.-),Reelin (EC 3.4.21.-),GO:0097114; GO:0008306; GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0016358; GO:0005615; GO:0010001; GO:0021766; GO:0007616; GO:0046872; GO:0001764; GO:0018108; GO:0032793; GO:0032008; GO:2000969; GO:0061003; GO:2000463; GO:1900273; GO:0010976; GO:0014068; GO:0061098; GO:0051057; GO:0090129; GO:0051968; GO:0097119; GO:0004712; GO:0005578; GO:0006508; GO:0097120; GO:0038026; GO:2000310; GO:0050795; GO:0048265; GO:0008236; GO:0021511; GO:0021517; GO:0070326,"N-methyl-D-aspartate receptor clustering; associative learning; axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; dendrite development; extracellular space; glial cell differentiation; hippocampus development; long-term memory; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of CREB transcription factor activity; positive regulation of TOR signaling cascade; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; positive regulation of dendritic spine morphogenesis; positive regulation of excitatory postsynaptic membrane potential; positive regulation of long-term synaptic potentiation; positive regulation of neuron projection development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of protein tyrosine kinase activity; positive regulation of small GTPase mediated signal transduction; positive regulation of synapse maturation; positive regulation of synaptic transmission, glutamatergic; postsynaptic density protein 95 clustering; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; receptor localization to synapse; reelin-mediated signaling pathway; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of behavior; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development; very-low-density lipoprotein particle receptor binding",PF02014;,1.00E-11,CHOYP_RELN.3.4,,,,,,,RELN_HUMAN,Homo sapiens (Human),"associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density protein 95 clustering [GO:0097119]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]" comp130899_c0_seq1,323,41.1765,0.73270716,12,1,,3.00E-17,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp130908_c0_seq1,1478,46.2111,0.36910741,71,31,,3.00E-42,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,2.00E-58,CHOYP_BIG3.1.1,,,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp130909_c1_seq1,359,41.2256,0.52631987,2,12,,4.00E-13,Q8N9H8,Probable exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3),Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;PF01927;,,,,,,,,,MUT7_HUMAN,Homo sapiens (Human), comp130909_c2_seq2,1513,44.8777,0.55226985,51,175,,3.00E-53,Q8N9H8,Probable exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3),Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;PF01927;,2.00E-15,CHOYP_LOC100370838.1.1,,,,,,,MUT7_HUMAN,Homo sapiens (Human), comp130910_c0_seq1,2050,40.7317,0.48268253,99692,314655,,0,P63245,"Guanine nucleotide-binding protein subunit beta-2-like 1 (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) (RACK1) [Cleaved into: Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed]","Receptor of activated protein C kinase 1 (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed]",GO:0042169; GO:0007049; GO:0008656; GO:0005856; GO:0030425; GO:0007369; GO:0008200; GO:0030496; GO:0030178; GO:0030308; GO:0050765; GO:0051898; GO:0017148; GO:0043025; GO:0005634; GO:0043204; GO:0048471; GO:0001891; GO:0043547; GO:0043065; GO:0030335; GO:2000543; GO:2001244; GO:0032436; GO:0032464; GO:0001934; GO:0005080; GO:0007205; GO:0030292; GO:0030971; GO:0051726; GO:0051302; GO:2000114; GO:0090003; GO:0048511; GO:0015935,SH2 domain binding; cell cycle; cysteine-type endopeptidase activator activity involved in apoptotic process; cytoskeleton; dendrite; gastrulation; ion channel inhibitor activity; midbody; negative regulation of Wnt receptor signaling pathway; negative regulation of cell growth; negative regulation of phagocytosis; negative regulation of protein kinase B signaling cascade; negative regulation of translation; neuronal cell body; nucleus; perikaryon; perinuclear region of cytoplasm; phagocytic cup; positive regulation of GTPase activity; positive regulation of apoptotic process; positive regulation of cell migration; positive regulation of gastrulation; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein homooligomerization; positive regulation of protein phosphorylation; protein kinase C binding; protein kinase C-activating G-protein coupled receptor signaling pathway; protein tyrosine kinase inhibitor activity; receptor tyrosine kinase binding; regulation of cell cycle; regulation of cell division; regulation of establishment of cell polarity; regulation of establishment of protein localization to plasma membrane; rhythmic process; small ribosomal subunit,PF00400;,0,CHOYP_GBLP.7.7,0,ruditapes2_lrc3101,,,,,GBLP_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; gastrulation [GO:0007369]; negative regulation of cell growth [GO:0030308]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of translation [GO:0017148]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cAMP catabolic process [GO:0030822]; positive regulation of cell migration [GO:0030335]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gastrulation [GO:2000543]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein homooligomerization [GO:0032464]; positive regulation of protein phosphorylation [GO:0001934]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of protein localization to plasma membrane [GO:0090003]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511] comp130911_c0_seq1,1298,41.2173,0.40197509,0,0,,,,,,,,,1.00E-110,CHOYP_BRAFLDRAFT_278625.1.2,,,,,,,,, comp130911_c0_seq2,1344,41.1458,0.40665445,1,7,,2.00E-66,Q9H3P7,Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7),"Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed]",GO:0005794; GO:0000139; GO:0000062; GO:0016021; GO:0005739; GO:0006694; GO:0006810,Golgi apparatus; Golgi membrane; fatty-acyl-CoA binding; integral to membrane; mitochondrion; steroid biosynthetic process; transport,PF00887;PF13897;,5.00E-15,CHOYP_BRAFLDRAFT_278625.2.2,,,,,,,GCP60_HUMAN,Homo sapiens (Human),steroid biosynthetic process [GO:0006694]; transport [GO:0006810] comp130912_c0_seq1,1191,46.1797,0.5043905,0,3,,3.00E-76,Q6PNC0,DmX-like protein 1 (X-like 1 protein),DmX-like protein 1 (X-like 1 protein),,,PF12234;PF00400;,,,,,,,,,DMXL1_MOUSE,Mus musculus (Mouse), comp130912_c0_seq2,3209,45.6529,0.56889789,111,74,,1.00E-128,Q8TDJ6,DmX-like protein 2 (Rabconnectin-3),DmX-like protein 2 (Rabconnectin-3),GO:0017137; GO:0030054; GO:0008021; GO:0030672,Rab GTPase binding; cell junction; synaptic vesicle; synaptic vesicle membrane,PF12234;PF00400;,4.00E-59,CHOYP_AGAP_AGAP010490.1.1,,,,,,,DMXL2_HUMAN,Homo sapiens (Human), comp130913_c0_seq2,1035,35.4589,1.06352756,44,30,,2.00E-29,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp130915_c0_seq1,771,43.3204,1.00823678,2602,417,,1.00E-22,Q7Z4M0,Meiotic recombination protein REC114-like,Meiotic recombination protein REC114,GO:0006310; GO:0007126,DNA recombination; meiosis,PF15165;,,,,,,,,,R114L_HUMAN,Homo sapiens (Human),DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321] comp130916_c0_seq1,2439,49.9795,0.76389091,154,109,,1.00E-62,Q5VT06,Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),GO:0005813; GO:0005737; GO:0005634; GO:0005819,centrosome; cytoplasm; nucleus; spindle,PF01302;,5.00E-50,CHOYP_CEP350.1.1,,,,,,,CE350_HUMAN,Homo sapiens (Human),microtubule anchoring [GO:0034453] comp130920_c0_seq1,1564,43.5422,0.59244839,26,32,,2.00E-105,Q9N0A8,Rho guanine nucleotide exchange factor 3,Rho guanine nucleotide exchange factor 3,GO:0005089; GO:0005737; GO:0035556; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cytoplasm; intracellular signal transduction; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,1.00E-92,CHOYP_ARHGEF3.1.1,,,,,,,ARHG3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023] comp130922_c1_seq1,730,40.5479,0.27194992,16,78,,8.00E-16,Q96PQ7,Kelch-like protein 5,Kelch-like protein 5,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF07707;PF00651;PF01344;,,,,,,,,,KLHL5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp130923_c0_seq1,1786,38.6338,0.40130955,4568,18072,,0,P48601,26S protease regulatory subunit 4 (P26s4),26S protease regulatory subunit 4 (P26s4),GO:0005524; GO:0008283; GO:0005737; GO:0000022; GO:0017111; GO:0005634; GO:0043161; GO:0008540; GO:0006974,"ATP binding; cell proliferation; cytoplasm; mitotic spindle elongation; nucleoside-triphosphatase activity; nucleus; proteasomal ubiquitin-dependent protein catabolic process; proteasome regulatory particle, base subcomplex; response to DNA damage stimulus",PF00004;,0,CHOYP_PRS4.1.1,4.00E-174,ruditapes2_c3508,,,,,PRS4_DROME,Drosophila melanogaster (Fruit fly),cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mitotic spindle assembly [GO:0090307]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp130926_c0_seq1,1232,45.8604,0.2350543,17,214,,2.00E-70,Q54IT3,Probable flavin-containing monoamine oxidase A (EC 1.4.3.4),Probable flavin-containing monoamine oxidase A (EC 1.4.3.4),GO:0016491,oxidoreductase activity,PF01593;,,,,,,,,,AOFA_DICDI,Dictyostelium discoideum (Slime mold), comp130928_c1_seq1,1439,37.665,0.55372472,24,46,,3.00E-22,Q5S1W2,Protein BONZAI 2,Protein BONZAI 2,GO:0006952; GO:0005886; GO:0009506,defense response; plasma membrane; plasmodesma,PF00168;PF07002;,,,,,,,,,BON2_ARATH,Arabidopsis thaliana (Mouse-ear cress),defense response [GO:0006952]; negative regulation of cell death [GO:0060548] comp130928_c1_seq2,1391,37.5988,0.57422388,9,35,,1.00E-81,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,1.00E-61,CHOYP_LOC100369190.1.1,3.00E-28,ruditapes2_c791,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp130929_c0_seq2,1480,35.473,0.41087248,55,149,,,,,,,,,,,1.00E-15,ruditapes_c24049,,,,,,, comp130930_c0_seq1,1250,38.08,0.36211692,353,3080,,3.00E-123,Q502K1,"Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1)","Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1)",GO:0004519; GO:0046872; GO:0005743; GO:0003676; GO:0090305,endonuclease activity; metal ion binding; mitochondrial inner membrane; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01223;,,,,,,,,,EXOG_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp130931_c0_seq1,1382,32.4891,0.55844972,1002,0,,3.00E-69,Q3KQ77,EF-hand calcium-binding domain-containing protein 1,EF-hand calcium-binding domain-containing protein 1,GO:0005509,calcium ion binding,PF13499;,2.00E-38,CHOYP_EFCAB1.1.1,,,,,,,EFCB1_XENLA,Xenopus laevis (African clawed frog), comp130938_c3_seq4,769,40.9623,0.93130298,0,0,,1.00E-07,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp130938_c3_seq7,376,52.1277,0.95012748,6,3,,4.00E-06,Q7JQ07,Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),GO:0003677; GO:0015074; GO:0006310; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA integration; DNA recombination; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF01359;,,,,,,,,,MOS1T_DROMA,Drosophila mauritiana (Fruit fly),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp130945_c0_seq3,524,36.8321,0.39937116,3,22,,1.00E-16,Q9V558,Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1),Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,1.00E-17,CHOYP_LOC100379072.1.1,,,,,,,CP4P1_DROME,Drosophila melanogaster (Fruit fly), comp130945_c1_seq1,474,40.2954,0.4913815,11,40,,7.00E-43,P78329,Leukotriene-B(4) omega-hydroxylase 1 (EC 1.14.13.30) (CYPIVF2) (Cytochrome P450 4F2) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 1),Phylloquinone omega-hydroxylase CYP4F2 (EC 1.14.13.194) (20-hydroxyeicosatetraenoic acid synthase) (20-HETE synthase) (EC 1.14.13.-) (Arachidonic acid omega-hydroxylase) (CYPIVF2) (Cytochrome P450 4F2) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 1) (Leukotriene-B(4) omega-hydroxylase 1) (EC 1.14.13.30),GO:0018685; GO:0052871; GO:0016324; GO:0008392; GO:0052869; GO:0017144; GO:0005789; GO:0019373; GO:0020037; GO:0005506; GO:0050051; GO:0030195; GO:0032304; GO:0097267; GO:0032305; GO:0003095; GO:0003091; GO:0055078; GO:0052872; GO:0000038; GO:0042360; GO:0042371; GO:0047057; GO:0006805,alkane 1-monooxygenase activity; alpha-tocopherol omega-hydroxylase activity; apical plasma membrane; arachidonic acid epoxygenase activity; arachidonic acid omega-hydroxylase activity; drug metabolic process; endoplasmic reticulum membrane; epoxygenase P450 pathway; heme binding; iron ion binding; leukotriene-B4 20-monooxygenase activity; negative regulation of blood coagulation; negative regulation of icosanoid secretion; omega-hydroxylase P450 pathway; positive regulation of icosanoid secretion; pressure natriuresis; renal water homeostasis; sodium ion homeostasis; tocotrienol omega-hydroxylase activity; very long-chain fatty acid metabolic process; vitamin E metabolic process; vitamin K biosynthetic process; vitamin-K-epoxide reductase (warfarin-sensitive) activity; xenobiotic metabolic process,PF00067;,,,,,,,,,CP4F2_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; blood coagulation [GO:0007596]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; leukotriene B4 catabolic process [GO:0036101]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid metabolic process [GO:0001676]; menaquinone catabolic process [GO:0042361]; negative regulation of icosanoid secretion [GO:0032304]; omega-hydroxylase P450 pathway [GO:0097267]; oxidation-reduction process [GO:0055114]; phylloquinone catabolic process [GO:0042376]; positive regulation of icosanoid secretion [GO:0032305]; pressure natriuresis [GO:0003095]; regulation of blood pressure [GO:0008217]; renal water homeostasis [GO:0003091]; sodium ion homeostasis [GO:0055078]; very long-chain fatty acid metabolic process [GO:0000038]; vitamin E metabolic process [GO:0042360]; vitamin K catabolic process [GO:0042377] comp130946_c0_seq2,1372,43.6589,0.61333009,0,0,,3.00E-135,Q8IZN3,Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,1.00E-125,CHOYP_ZDH14.1.2,,,,,,,ZDH14_HUMAN,Homo sapiens (Human),protein palmitoylation [GO:0018345] comp130946_c0_seq3,1059,39.9433,0.54796417,0,0,,,,,,,,,5.00E-39,CHOYP_ZDHHC14.1.2,,,,,,,,, comp130946_c0_seq5,1318,43.8543,0.63278878,0,0,,1.00E-135,Q8IZN3,Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,5.00E-123,CHOYP_ZDHHC14.2.2,,,,,,,ZDH14_HUMAN,Homo sapiens (Human),protein palmitoylation [GO:0018345] comp130946_c0_seq9,861,40.8827,0.53120207,0,0,,,,,,,,,3.00E-28,CHOYP_ZDH14.1.2,,,,,,,,, comp130947_c0_seq1,1744,43.9794,0.73583647,104,64,,1.00E-18,Q8I7P9,Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305; GO:0005634; GO:0008233; GO:0006508; GO:0006313,"DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; peptidase activity; proteolysis; transposition, DNA-mediated",PF00665;PF00078;,7.00E-78,CHOYP_LOC100369720.1.1,1.00E-28,ruditapes_c18113,,,,,POL5_DROME,Drosophila melanogaster (Fruit fly),"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp130950_c0_seq1,1416,43.3616,0.56239234,50,99,,2.00E-170,Q58CU2,Band 4.1-like protein 5,Band 4.1-like protein 5,GO:0005912; GO:0005737; GO:0005856; GO:0019898,adherens junction; cytoplasm; cytoskeleton; extrinsic to membrane,PF08736;PF09380;PF00373;PF09379;,4.00E-137,CHOYP_AGAP_AGAP004136.3.3,,,,,,,E41L5_BOVIN,Bos taurus (Bovine), comp130950_c0_seq2,798,38.7218,0.4096042,0,0,,3.00E-06,Q54EW0,FERM domain-containing protein A,FERM domain-containing protein A,GO:0015629; GO:0030036; GO:0048870; GO:0022408; GO:0010812; GO:0046956; GO:0031288,actin cytoskeleton; actin cytoskeleton organization; cell motility; negative regulation of cell-cell adhesion; negative regulation of cell-substrate adhesion; positive phototaxis; sorocarp morphogenesis,PF16511;PF00373;PF09379;,,,,,,,,,FRMA_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell motility [GO:0048870]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-substrate adhesion [GO:0010812]; positive phototaxis [GO:0046956]; sorocarp morphogenesis [GO:0031288] comp130954_c0_seq2,516,38.7597,0.6209612,22,0,,9.00E-07,Q3TPE9,Ankyrin repeat and MYND domain-containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,GO:0005929; GO:0046872,cilium; metal ion binding,PF12796;PF01753;,,,,,,,,,ANKY2_MOUSE,Mus musculus (Mouse), comp130954_c0_seq3,523,37.4761,0.38196537,8,0,,2.00E-06,Q54ZX8,SET and MYND domain-containing protein DDB_G0277331 (EC 2.1.1.-),SET and MYND domain-containing protein DDB_G0277331 (EC 2.1.1.-),GO:0046872; GO:0008168,metal ion binding; methyltransferase activity,PF00856;PF01753;,,,,,,,,,Y7331_DICDI,Dictyostelium discoideum (Slime mold), comp130955_c0_seq12,2441,45.1864,0.46576089,0,0,,2.00E-161,Q9VI75,Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180),Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180),GO:0005545; GO:0005794; GO:0030276; GO:0030118; GO:0048268; GO:0005905; GO:0007270; GO:0007269; GO:0042331; GO:0006898; GO:0008021; GO:0016183,1-phosphatidylinositol binding; Golgi apparatus; clathrin binding; clathrin coat; clathrin coat assembly; coated pit; neuron-neuron synaptic transmission; neurotransmitter secretion; phototaxis; receptor-mediated endocytosis; synaptic vesicle; synaptic vesicle coating,PF07651;,,,,,,,,,PICA_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; neuron-neuron synaptic transmission [GO:0007270]; neurotransmitter secretion [GO:0007269]; phototaxis [GO:0042331]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489] comp130955_c0_seq13,1299,39.9538,0.62058097,8,0,,3.00E-166,Q9VI75,Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180),Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180),GO:0005545; GO:0005794; GO:0030276; GO:0030118; GO:0048268; GO:0005905; GO:0007270; GO:0007269; GO:0042331; GO:0006898; GO:0008021; GO:0016183,1-phosphatidylinositol binding; Golgi apparatus; clathrin binding; clathrin coat; clathrin coat assembly; coated pit; neuron-neuron synaptic transmission; neurotransmitter secretion; phototaxis; receptor-mediated endocytosis; synaptic vesicle; synaptic vesicle coating,PF07651;,7.00E-178,CHOYP_LOC654860.3.3,,,,,,,PICA_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; neuron-neuron synaptic transmission [GO:0007270]; neurotransmitter secretion [GO:0007269]; phototaxis [GO:0042331]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489] comp130955_c0_seq2,1281,40.0468,0.62679947,0,0,,5.00E-159,O55012,Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) (rCALM),Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) (rCALM),GO:0005545; GO:0005794; GO:0017124; GO:0007409; GO:0030276; GO:0030118; GO:0048268; GO:0005905; GO:0048813; GO:0005768; GO:0097481; GO:0005634; GO:0045211; GO:0042734; GO:0006898; GO:0030100; GO:0051223; GO:0008021,1-phosphatidylinositol binding; Golgi apparatus; SH3 domain binding; axonogenesis; clathrin binding; clathrin coat; clathrin coat assembly; coated pit; dendrite morphogenesis; endosome; neuronal postsynaptic density; nucleus; postsynaptic membrane; presynaptic membrane; receptor-mediated endocytosis; regulation of endocytosis; regulation of protein transport; synaptic vesicle,PF07651;,8.00E-177,CHOYP_LOC654860.1.3,,,,,,,PICA_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; cargo loading into vesicle [GO:0035459]; cell proliferation [GO:0008283]; clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; iron ion homeostasis [GO:0055072]; iron ion import into cell [GO:0097459]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of beta-amyloid formation [GO:1902004]; positive regulation of neuron death [GO:1901216]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; synaptic vesicle maturation [GO:0016188]; vesicle-mediated transport [GO:0016192] comp130955_c0_seq4,2459,45.0996,0.46410875,0,0,,1.00E-161,Q9VI75,Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180),Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180),GO:0005545; GO:0005794; GO:0030276; GO:0030118; GO:0048268; GO:0005905; GO:0007270; GO:0007269; GO:0042331; GO:0006898; GO:0008021; GO:0016183,1-phosphatidylinositol binding; Golgi apparatus; clathrin binding; clathrin coat; clathrin coat assembly; coated pit; neuron-neuron synaptic transmission; neurotransmitter secretion; phototaxis; receptor-mediated endocytosis; synaptic vesicle; synaptic vesicle coating,PF07651;,,,,,,,,,PICA_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; neuron-neuron synaptic transmission [GO:0007270]; neurotransmitter secretion [GO:0007269]; phototaxis [GO:0042331]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489] comp130955_c0_seq9,2693,45.674,0.48442866,0,0,,,,,,,,,1.00E-177,CHOYP_LOC654860.3.3,,,,,,,,, comp130958_c0_seq1,1616,44.3069,0.50882308,2185,683,,4.00E-137,Q9CUL5,IQ and AAA domain-containing protein 1,IQ and AAA domain-containing protein 1,GO:0005524; GO:0017111,ATP binding; nucleoside-triphosphatase activity,PF00004;,0,CHOYP_IQCA1.3.3,4.00E-59,ruditapes2_lrc4700,,,,,IQCA1_MOUSE,Mus musculus (Mouse), comp130959_c0_seq1,802,46.01,0.43821315,50,38,,,,,,,,,4.00E-109,CHOYP_LOC100375650.1.1,,,,,,,,, comp130959_c1_seq1,1383,41.504,0.44047861,90,29,,6.00E-133,Q98SP7,Bardet-Biedl syndrome 2 protein homolog,Bardet-Biedl syndrome 2 protein homolog,GO:0070121; GO:0042384; GO:0060170; GO:0005737; GO:0007368; GO:0046907; GO:0032402; GO:0005815; GO:0051877,Kupffer's vesicle development; cilium assembly; cilium membrane; cytoplasm; determination of left/right symmetry; intracellular transport; melanosome transport; microtubule organizing center; pigment granule aggregation in cell center,PF14782;PF14783;PF14781;,,,,,,,,,BBS2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; nonmotile primary cilium assembly [GO:0035058]; pigment granule aggregation in cell center [GO:0051877]; protein localization to ciliary membrane [GO:1903441] comp130961_c0_seq1,807,42.7509,0.46227439,30,10,,2.00E-61,Q8BLN6,Protein unc-80 homolog (mUNC-80),Protein unc-80 homolog (mUNC-80),GO:0016021,integral to membrane,PF15778;,8.00E-67,CHOYP_PHUM_PHUM244880.2.2,,,,,,,UNC80_MOUSE,Mus musculus (Mouse), comp130962_c0_seq1,2344,32.2952,0.63425783,13038,939,,2.00E-08,Q9ZDC6,Probable cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome aa3 subunit 2) (Cytochrome c oxidase polypeptide II),Probable cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome aa3 subunit 2) (Cytochrome c oxidase polypeptide II),GO:0005507; GO:0004129; GO:0022900; GO:0016021; GO:0005886; GO:0070469,copper ion binding; cytochrome-c oxidase activity; electron transport chain; integral to membrane; plasma membrane; respiratory chain,PF00116;PF02790;,,,,,,,,,COX2_RICPR,Rickettsia prowazekii (strain Madrid E),electron transport chain [GO:0022900] comp130965_c0_seq1,1317,33.1815,0.55859324,3959,16752,,4.00E-39,P62321,Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF),Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF),GO:0003723; GO:0008380; GO:0006397; GO:0005681,RNA binding; RNA splicing; mRNA processing; spliceosomal complex,PF01423;,1.00E-53,CHOYP_ISCW_ISCW012036.1.1,8.00E-74,ruditapes2_c474,,,,,RUXF_XENLA,Xenopus laevis (African clawed frog),spliceosomal snRNP assembly [GO:0000387] comp130966_c0_seq1,1492,39.008,0.25530107,7,14,,3.00E-122,P48637,Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase),Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase),GO:0005524; GO:0007568; GO:0005829; GO:0043295; GO:1901687; GO:0004363; GO:0016594; GO:0000287; GO:0007399; GO:0042803; GO:0043200; GO:0046686; GO:0031667; GO:0006979; GO:0034612; GO:0006805,ATP binding; aging; cytosol; glutathione binding; glutathione derivative biosynthetic process; glutathione synthase activity; glycine binding; magnesium ion binding; nervous system development; protein homodimerization activity; response to amino acid stimulus; response to cadmium ion; response to nutrient levels; response to oxidative stress; response to tumor necrosis factor; xenobiotic metabolic process,PF03917;PF03199;,,,,,,,,,GSHB_HUMAN,Homo sapiens (Human),aging [GO:0007568]; cellular amino acid metabolic process [GO:0006520]; glutathione biosynthetic process [GO:0006750]; nervous system development [GO:0007399]; response to amino acid [GO:0043200]; response to cadmium ion [GO:0046686]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to xenobiotic stimulus [GO:0009410] comp130969_c0_seq2,1685,47.2404,0.37337953,50,7,,2.00E-160,Q9BZH6,WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15),WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15),GO:0005929; GO:0016021; GO:0005765; GO:0005634,cilium; integral to membrane; lysosomal membrane; nucleus,,7.00E-97,CHOYP_WDR11.2.2,,,,,,,WDR11_HUMAN,Homo sapiens (Human), comp130970_c1_seq4,561,31.3725,0.36290959,17,112,,1.00E-33,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,1.00E-24,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp130972_c0_seq1,648,33.3333,0.67604328,84,763,,2.00E-29,Q91X96,Guanine nucleotide exchange factor MSS4 (Rab-interacting factor),Guanine nucleotide exchange factor MSS4 (Rab-interacting factor),GO:0005085; GO:0015031; GO:0007264; GO:0008270,guanyl-nucleotide exchange factor activity; protein transport; small GTPase mediated signal transduction; zinc ion binding,PF04421;,9.00E-15,CHOYP_LOC100708329.1.1,4.00E-36,ruditapes_c399,,,,,MSS4_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp130973_c0_seq1,995,45.0251,0.39228895,0,0,,,,,,,,,,,2.00E-29,ruditapes_c10341,,,,,,, comp130973_c0_seq2,1101,44.7775,0.39754723,12,0,,1.00E-38,Q7A5L8,L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),GO:0004794; GO:0070689; GO:0000166; GO:0030170,L-threonine ammonia-lyase activity; L-threonine catabolic process to propionate; nucleotide binding; pyridoxal phosphate binding,PF00291;,7.00E-120,CHOYP_LOC100375322.1.1,,,,,,,TDCB_STAAN,Staphylococcus aureus (strain N315),L-threonine catabolic process to propionate [GO:0070689] comp130981_c0_seq1,896,37.7232,0.87556597,151,788,,1.00E-31,Q2KJG4,Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),GO:0005783; GO:0005789; GO:0008047; GO:0006750; GO:0004602; GO:0004364; GO:0016021; GO:0019370; GO:0004464; GO:0005635; GO:0005886; GO:0043085,endoplasmic reticulum; endoplasmic reticulum membrane; enzyme activator activity; glutathione biosynthetic process; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; leukotriene biosynthetic process; leukotriene-C4 synthase activity; nuclear envelope; plasma membrane; positive regulation of catalytic activity,PF01124;,,,,,,,,,MGST2_BOVIN,Bos taurus (Bovine),glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370] comp130984_c0_seq1,1087,38.0865,0.99549634,22,240,,8.00E-47,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,,,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp130984_c1_seq1,328,43.5976,0.98661453,2,21,,2.00E-22,Q1W674,Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II),Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II),GO:0005524; GO:0006096; GO:0004396,ATP binding; glycolysis; hexokinase activity,PF00349;PF03727;,,,,,,,,,HXK2_PIG,Sus scrofa (Pig),cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318] comp130989_c0_seq1,2132,41.9794,0.46322737,940,2916,,0,Q5ZLM0,Parafibromin (Cell division cycle protein 73 homolog),Parafibromin (Cell division cycle protein 73 homolog),GO:0016593; GO:0000993; GO:0007049; GO:0071222; GO:0001711; GO:0033523; GO:0010390; GO:0006378; GO:2000134; GO:0008285; GO:0050680; GO:0048147; GO:0045638; GO:0000122; GO:0030177; GO:0031442; GO:0032968; GO:0045944; GO:0031648; GO:0019827; GO:0006351,"Cdc73/Paf1 complex; RNA polymerase II core binding; cell cycle; cellular response to lipopolysaccharide; endodermal cell fate commitment; histone H2B ubiquitination; histone monoubiquitination; mRNA polyadenylation; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of fibroblast proliferation; negative regulation of myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of Wnt receptor signaling pathway; positive regulation of mRNA 3'-end processing; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein destabilization; stem cell maintenance; transcription, DNA-dependent",PF05179;PF16050;,0,CHOYP_CDC73.1.1,,,,,,,CDC73_CHICK,Gallus gallus (Chicken),cell cycle [GO:0007049]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; mRNA polyadenylation [GO:0006378]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; protein destabilization [GO:0031648]; stem cell population maintenance [GO:0019827]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp130992_c0_seq1,1345,36.1338,0.89774817,1,143,,3.00E-95,O02367,Calmodulin (CaM) (Ci-CaM),Calmodulin (CaM) (Ci-CaM),GO:0005509,calcium ion binding,PF13499;,8.00E-108,CHOYP_LOC100372664.2.2,7.00E-125,ruditapes_lrc29067,,,,,CALM_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis), comp130992_c0_seq2,1387,35.6164,0.89722089,7,120,,4.00E-95,Q95NR9,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,2.00E-108,CHOYP_LOC100533341.1.1,2.00E-112,ruditapes_lrc37613,,,,,CALM_METSE,Metridium senile (Brown sea anemone) (Frilled sea anemone), comp130998_c0_seq2,1237,39.2078,0.63217063,0,805,female,3.00E-07,P04570,"Sarcoplasmic calcium-binding proteins II, V, VI, and VII (SCP II) (SCP V) (SCP VI) (SCP VII)","Sarcoplasmic calcium-binding proteins II, V, VI, and VII (SCP II) (SCP V) (SCP VI) (SCP VII)",GO:0005509,calcium ion binding,PF13833;,,,,,,,,,SCP2_BRALA,Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum), comp131000_c0_seq1,2010,35.2239,0.61089942,29,70,,5.00E-31,Q134T2,50S ribosomal protein L2,50S ribosomal protein L2,GO:0015934; GO:0019843; GO:0003735; GO:0016740; GO:0006412,large ribosomal subunit; rRNA binding; structural constituent of ribosome; transferase activity; translation,PF00181;PF03947;,,,,,,,,,RL2_RHOPS,Rhodopseudomonas palustris (strain BisB5),translation [GO:0006412] comp131000_c0_seq2,2029,35.584,0.60855076,35,282,,5.00E-72,Q498T4,"39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)","39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF00181;PF03947;,,,,,,,,,RM02_RAT,Rattus norvegicus (Rat),mitochondrial translation [GO:0032543] comp131003_c0_seq1,306,46.0784,0.2471846,17,11,,3.00E-44,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,8.00E-62,CHOYP_DNAH6.2.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp131030_c0_seq1,1186,41.5683,0.58611537,0,0,,7.00E-13,Q8BYK5,Phosphatase and actin regulator 3 (Scaffold-associated PP1-inhibiting protein) (Scapinin),Phosphatase and actin regulator 3 (Scaffold-associated PP1-inhibiting protein) (Scapinin),GO:0016363; GO:0004864,nuclear matrix; protein phosphatase inhibitor activity,PF02755;,,,,,,,,,PHAR3_MOUSE,Mus musculus (Mouse), comp131030_c0_seq2,501,39.3214,0.42070145,1,0,,1.00E-16,Q6GLU8,Phosphatase and actin regulator 1,Phosphatase and actin regulator 1,GO:0003779; GO:0031532; GO:0031032; GO:0030054; GO:0005829; GO:0005634; GO:0004864; GO:0043149; GO:0045202,actin binding; actin cytoskeleton reorganization; actomyosin structure organization; cell junction; cytosol; nucleus; protein phosphatase inhibitor activity; stress fiber assembly; synapse,PF02755;,5.00E-29,CHOYP_KDM1A.1.1,,,,,,,PHAR1_XENLA,Xenopus laevis (African clawed frog),actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; stress fiber assembly [GO:0043149] comp131030_c0_seq3,1581,43.0108,0.58864376,19,72,,3.00E-15,Q501J7,Phosphatase and actin regulator 4 (Protein Humpty dumpty) (Humdy),Phosphatase and actin regulator 4 (Protein Humpty dumpty) (Humdy),GO:0007266; GO:0003779; GO:0030036; GO:0061386; GO:0005737; GO:0048484; GO:0005622; GO:0030027; GO:2001045; GO:0001755; GO:0001843; GO:0008157; GO:0004864; GO:0071862; GO:0051726,Rho protein signal transduction; actin binding; actin cytoskeleton organization; closure of optic fissure; cytoplasm; enteric nervous system development; intracellular; lamellipodium; negative regulation of integrin-mediated signaling pathway; neural crest cell migration; neural tube closure; protein phosphatase 1 binding; protein phosphatase inhibitor activity; protein phosphatase type 1 activator activity; regulation of cell cycle,PF02755;,,,4.00E-41,ruditapes_c13312,,,,,PHAR4_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; closure of optic fissure [GO:0061386]; enteric nervous system development [GO:0048484]; negative regulation of integrin-mediated signaling pathway [GO:2001045]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of catalytic activity [GO:0043085]; regulation of cell cycle [GO:0051726]; Rho protein signal transduction [GO:0007266] comp131032_c0_seq1,1437,35.6994,1.18030153,4305,148,,,,,,,,,1.00E-16,CHOYP_BRAFLDRAFT_117275.1.1,,,,,,,,, comp131035_c0_seq1,1316,49.924,0.52876781,34,35,,7.00E-93,O93574,Reelin (EC 3.4.21.-) (Fragment),Reelin (EC 3.4.21.-) (Fragment),GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0005615; GO:0010001; GO:0046872; GO:0001764; GO:0018108; GO:0045860; GO:0051057; GO:0004712; GO:0005578; GO:0006508; GO:0048265; GO:0008236; GO:0021511; GO:0021517,axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; extracellular space; glial cell differentiation; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of protein kinase activity; positive regulation of small GTPase mediated signal transduction; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development,PF07974;PF12661;,6.00E-103,CHOYP_RELN.3.4,,,,,,,RELN_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517] comp131035_c0_seq2,1005,47.3632,0.55447747,0,1,,,,,,,,,1.00E-46,CHOYP_RELN.4.4,,,,,,,,, comp131035_c1_seq1,627,47.0494,0.6086972,41,27,,9.00E-06,Q8I7T3,Substrate-adhesion molecule,Substrate-adhesion molecule,GO:0015629; GO:0007015; GO:0005938; GO:0000902; GO:0031589; GO:0016021; GO:0000281; GO:0006909; GO:0005886; GO:0034394; GO:0050821,actin cytoskeleton; actin filament organization; cell cortex; cell morphogenesis; cell-substrate adhesion; integral to membrane; mitotic cytokinesis; phagocytosis; plasma membrane; protein localization to cell surface; protein stabilization,,7.00E-54,CHOYP_RELN.3.4,,,,,,,SADA_DICDI,Dictyostelium discoideum (Slime mold),actin filament organization [GO:0007015]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; protein localization to cell surface [GO:0034394]; protein stabilization [GO:0050821] comp131035_c2_seq1,901,46.7259,0.41142178,67,59,,2.00E-65,P78509,Reelin (EC 3.4.21.-),Reelin (EC 3.4.21.-),GO:0097114; GO:0008306; GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0016358; GO:0005615; GO:0010001; GO:0021766; GO:0007616; GO:0046872; GO:0001764; GO:0018108; GO:0032793; GO:0032008; GO:2000969; GO:0061003; GO:2000463; GO:1900273; GO:0010976; GO:0014068; GO:0061098; GO:0051057; GO:0090129; GO:0051968; GO:0097119; GO:0004712; GO:0005578; GO:0006508; GO:0097120; GO:0038026; GO:2000310; GO:0050795; GO:0048265; GO:0008236; GO:0021511; GO:0021517; GO:0070326,"N-methyl-D-aspartate receptor clustering; associative learning; axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; dendrite development; extracellular space; glial cell differentiation; hippocampus development; long-term memory; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of CREB transcription factor activity; positive regulation of TOR signaling cascade; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; positive regulation of dendritic spine morphogenesis; positive regulation of excitatory postsynaptic membrane potential; positive regulation of long-term synaptic potentiation; positive regulation of neuron projection development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of protein tyrosine kinase activity; positive regulation of small GTPase mediated signal transduction; positive regulation of synapse maturation; positive regulation of synaptic transmission, glutamatergic; postsynaptic density protein 95 clustering; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; receptor localization to synapse; reelin-mediated signaling pathway; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of behavior; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development; very-low-density lipoprotein particle receptor binding",PF02014;,,,,,,,,,RELN_HUMAN,Homo sapiens (Human),"associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density protein 95 clustering [GO:0097119]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]" comp131043_c0_seq1,1526,38.6632,0.84989775,0,0,,6.00E-10,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp131044_c0_seq1,1309,36.9748,0.56477235,57,158,,5.00E-09,Q0VEE6,Zinc finger protein 800,Zinc finger protein 800,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16622;,,,,,,,,,ZN800_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131045_c1_seq4,1564,37.532,0.8326243,12,90,,2.00E-07,Q01373,Peroxisomal hydratase-dehydrogenase-epimerase (HDE) (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.119); (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12)],Peroxisomal hydratase-dehydrogenase-epimerase (HDE) (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.119); (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12)],GO:0006635; GO:0016853; GO:0016829; GO:0016616; GO:0005777,"fatty acid beta-oxidation; isomerase activity; lyase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; peroxisome",PF00106;PF01575;,,,,,,,,,FOX2_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),fatty acid beta-oxidation [GO:0006635] comp131045_c1_seq5,1660,38.012,0.69505026,0,0,,8.00E-48,Q8VCC1,15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1),15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1),GO:0016404; GO:0070403; GO:0016323; GO:0005737; GO:0097070; GO:0007565; GO:0045786; GO:0005634; GO:0030728; GO:0007567; GO:0004957; GO:0006693; GO:0070493; GO:0007179,15-hydroxyprostaglandin dehydrogenase (NAD+) activity; NAD+ binding; basolateral plasma membrane; cytoplasm; ductus arteriosus closure; female pregnancy; negative regulation of cell cycle; nucleus; ovulation; parturition; prostaglandin E receptor activity; prostaglandin metabolic process; thrombin receptor signaling pathway; transforming growth factor beta receptor signaling pathway,PF00106;,,,,,,,,,PGDH_MOUSE,Mus musculus (Mouse),ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; thrombin receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp131047_c0_seq2,382,40.3141,0.19948053,15,114,,2.00E-14,O08997,Copper transport protein ATOX1 (Metal transport protein ATX1),Copper transport protein ATOX1 (Metal transport protein ATX1),GO:0006878; GO:0016531; GO:0006825; GO:0006979,cellular copper ion homeostasis; copper chaperone activity; copper ion transport; response to oxidative stress,PF00403;,,,,,,,,,ATOX1_MOUSE,Mus musculus (Mouse),cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; intracellular copper ion transport [GO:0015680]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302] comp131051_c0_seq1,915,36.7213,0.35949807,577,434,,5.00E-44,Q2KIP7,Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2),Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2),GO:0042772; GO:0008432; GO:0051301; GO:0005737; GO:0006302; GO:0007067; GO:0060564; GO:0005634; GO:0033138; GO:0045893; GO:0001558; GO:0005819; GO:0006351; GO:0016035,"DNA damage response, signal transduction resulting in transcription; JUN kinase binding; cell division; cytoplasm; double-strand break repair; mitosis; negative regulation of mitotic anaphase-promoting complex activity; nucleus; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription, DNA-dependent; regulation of cell growth; spindle; transcription, DNA-dependent; zeta DNA polymerase complex",PF02301;,9.00E-23,CHOYP_LOC100313650.1.1,,,,,,,MD2L2_BOVIN,Bos taurus (Bovine),"cell division [GO:0051301]; DNA damage response, signal transduction resulting in transcription [GO:0042772]; double-strand break repair [GO:0006302]; mitotic nuclear division [GO:0007067]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell growth [GO:0001558]; transcription, DNA-templated [GO:0006351]" comp131052_c1_seq1,1410,41.3475,0.50114864,6,42,,0,Q9Z2K9,Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase),Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase),GO:0006103; GO:0051287; GO:0005737; GO:0006097; GO:0004450; GO:0006102; GO:0000287; GO:0006099,2-oxoglutarate metabolic process; NAD binding; cytoplasm; glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; isocitrate metabolic process; magnesium ion binding; tricarboxylic acid cycle,PF00180;,0,CHOYP_IDHC.1.1,7.00E-138,ruditapes_c8987,,,,,IDHC_MICME,Microtus mexicanus (Mexican vole),2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099] comp131053_c0_seq2,1428,40.6863,0.39571162,2403,15350,,,,,,,,,,,5.00E-51,ruditapes_c20573,,,,,,, comp131057_c0_seq1,1218,37.3563,0.62016243,83,18497,female>male,2.00E-08,P02257,"Histone H1, gonadal (Fragment)","Histone H1, gonadal (Fragment)",GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00538;,,,,,,,,,H1_ECHCR,Echinolampas crassa (Sea urchin) (Palaeolampas crassa),nucleosome assembly [GO:0006334] comp131058_c0_seq1,2294,38.5789,0.70506926,6420,13,male>female,3.00E-38,Q4V7B5,Coiled-coil domain-containing protein 105,Coiled-coil domain-containing protein 105,GO:0005874; GO:0000226,microtubule; microtubule cytoskeleton organization,,5.00E-170,CHOYP_LOC100371590.1.1,,,,,,,CC105_RAT,Rattus norvegicus (Rat), comp131059_c0_seq1,779,38.6393,0.27557014,59,423,,7.00E-63,Q8VBV7,COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (JAB1-containing signalosome subunit 8),COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (JAB1-containing signalosome subunit 8),GO:0008180; GO:0010388; GO:0005737,COP9 signalosome; cullin deneddylation; cytoplasm,PF10075;,3.00E-22,CHOYP_CSN8.1.1,2.00E-47,ruditapes_c22498,,,,,CSN8_MOUSE,Mus musculus (Mouse),activation of NF-kappaB-inducing kinase activity [GO:0007250]; COP9 signalosome assembly [GO:0010387]; cullin deneddylation [GO:0010388]; negative regulation of cell proliferation [GO:0008285] comp131060_c0_seq1,1362,42.9515,1.21796656,0,0,,2.00E-96,P58421,Frizzled-5 (Fz-5) (Xfz5),Frizzled-5 (Fz-5) (Xfz5),GO:0004930; GO:0016055; GO:0042813; GO:0043010; GO:0016021; GO:0048666; GO:0005886; GO:0045595; GO:0042127,G-protein coupled receptor activity; Wnt receptor signaling pathway; Wnt-activated receptor activity; camera-type eye development; integral to membrane; neuron development; plasma membrane; regulation of cell differentiation; regulation of cell proliferation,PF01534;PF01392;,3.00E-56,CHOYP_LOC100313610.1.2,,,,,,,FZD5_XENLA,Xenopus laevis (African clawed frog),camera-type eye development [GO:0043010]; neuron development [GO:0048666]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127] comp131060_c0_seq2,1478,42.0839,1.2460248,1,6,,1.00E-18,Q9NBW1,Frizzled-4 (dFz4),Frizzled-4 (dFz4),GO:0004930; GO:0030165; GO:0042813; GO:0017147; GO:0007420; GO:0060070; GO:0042995; GO:0005737; GO:0009790; GO:0008406; GO:0016021; GO:0005886; GO:0001944,G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; brain development; canonical Wnt receptor signaling pathway; cell projection; cytoplasm; embryo development; gonad development; integral to membrane; plasma membrane; vasculature development,PF01534;PF01392;,2.00E-58,CHOYP_LOC100313610.2.2,,,,,,,FRIZ4_DROME,Drosophila melanogaster (Fruit fly),canonical Wnt signaling pathway [GO:0060070]; G-protein coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; non-canonical Wnt signaling pathway [GO:0035567]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] comp131071_c0_seq1,1024,32.5195,0.46739671,196,743,,2.00E-09,Q8TAE8,"Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)","Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)",GO:0007049; GO:0005739; GO:0019048; GO:0005634,cell cycle; mitochondrion; modulation by virus of host morphology or physiology; nucleus,PF10147;,,,,,,,,,G45IP_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cell proliferation [GO:0008284]; positive regulation of oxidative phosphorylation [GO:1903862]; viral process [GO:0016032] comp131077_c0_seq1,1927,41.4115,0.49668255,125,262,,7.00E-88,A4QNN3,Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30),Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30),GO:0008234; GO:0016021; GO:0005741; GO:0004221; GO:0006511,cysteine-type peptidase activity; integral to membrane; mitochondrial outer membrane; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP30_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mitochondrial fusion [GO:0008053]; mitophagy [GO:0000422]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]; ubiquitin-dependent protein catabolic process [GO:0006511] comp131077_c1_seq1,769,45.9038,1.16284497,22,48,,1.00E-27,Q9CQ66,Tctex1 domain-containing protein 2,Tctex1 domain-containing protein 2,,,PF03645;,2.00E-12,CHOYP_LOC588988.1.1,,,,,,,TC1D2_MOUSE,Mus musculus (Mouse), comp131085_c0_seq1,2482,42.4255,0.29578736,144,302,,3.00E-58,Q9V727,Polycomb protein Asx (Additional sex combs),Polycomb protein Asx (Additional sex combs),GO:0003677; GO:0035517; GO:0007469; GO:0007475; GO:0001709; GO:0000785; GO:0003682; GO:0046872; GO:0035522; GO:0045892; GO:0045893; GO:0045498; GO:0035186; GO:0006351; GO:0035800,"DNA binding; PR-DUB complex; antennal development; apposition of dorsal and ventral imaginal disc-derived wing surfaces; cell fate determination; chromatin; chromatin binding; metal ion binding; monoubiquitinated histone H2A deubiquitination; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; sex comb development; syncytial blastoderm mitotic cell cycle; transcription, DNA-dependent; ubiquitin-specific protease activator activity",PF13919;PF13922;,6.00E-68,CHOYP_LOC584010.1.1,,,,,,,ASX_DROME,Drosophila melanogaster (Fruit fly),"antennal development [GO:0007469]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; cell fate determination [GO:0001709]; chromatin silencing [GO:0006342]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of gene expression [GO:0010468]; regulation of ubiquitin-specific protease activity [GO:2000152]; sex comb development [GO:0045498]; syncytial blastoderm mitotic cell cycle [GO:0035186]; transcription, DNA-templated [GO:0006351]" comp131086_c1_seq1,507,38.4615,0.85558228,18,138,,5.00E-25,Q22460,Beta carbonic anhydrase 1 (EC 4.2.1.1),Beta carbonic anhydrase 1 (EC 4.2.1.1),GO:0004089; GO:0008270,carbonate dehydratase activity; zinc ion binding,PF00484;,,,,,,,,,BCA1_CAEEL,Caenorhabditis elegans, comp131086_c2_seq1,446,40.583,0.71126429,12,62,,3.00E-10,P27134,Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase),Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase),GO:0015976; GO:0004089; GO:0008270,carbon utilization; carbonate dehydratase activity; zinc ion binding,PF00484;,,,,,,,,,CYNT_SYNE7,Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2),carbon utilization [GO:0015976] comp131087_c0_seq1,660,41.8182,0.7376073,2041,7789,,2.00E-24,Q3UQA7,Selenoprotein H (SelH),Selenoprotein H (SelH),GO:0045454; GO:0008430,cell redox homeostasis; selenium binding,PF10262;,,,5.00E-60,ruditapes_c14704,,,,,SELH_MOUSE,Mus musculus (Mouse), comp131091_c0_seq4,1458,41.4952,0.54228457,1,0,,4.00E-154,Q5R7R6,Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4),Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4),GO:0000139; GO:0015031,Golgi membrane; protein transport,PF08318;,,,,,,,,,COG4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp131091_c0_seq5,1453,41.3627,0.53137415,0,0,,5.00E-151,Q5R7R6,Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4),Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4),GO:0000139; GO:0015031,Golgi membrane; protein transport,PF08318;,3.00E-126,CHOYP_BRAFLDRAFT_92601.1.1,,,,,,,COG4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp131093_c2_seq2,1373,39.3299,0.32389501,0,0,,1.00E-54,Q865F1,Microsomal triglyceride transfer protein large subunit,Microsomal triglyceride transfer protein large subunit,GO:0005783; GO:0008289; GO:0005319,endoplasmic reticulum; lipid binding; lipid transporter activity,PF01347;,,,,,,,,,MTP_PIG,Sus scrofa (Pig),phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; triglyceride transport [GO:0034197] comp131093_c2_seq3,1106,40.1447,0.29901537,0,0,,,,,,,,,4.00E-16,CHOYP_BRAFLDRAFT_123736.1.1,,,,,,,,, comp131093_c2_seq4,1384,39.6676,0.31719853,0,0,,4.00E-48,O08601,Microsomal triglyceride transfer protein large subunit,Microsomal triglyceride transfer protein large subunit,GO:0005794; GO:0042632; GO:0008203; GO:0005783; GO:0008289; GO:0005319; GO:0042953; GO:0006497; GO:0006641,Golgi apparatus; cholesterol homeostasis; cholesterol metabolic process; endoplasmic reticulum; lipid binding; lipid transporter activity; lipoprotein transport; protein lipidation; triglyceride metabolic process,PF01347;,1.00E-23,CHOYP_BRAFLDRAFT_123736.1.1,,,,,,,MTP_MOUSE,Mus musculus (Mouse),cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; circadian rhythm [GO:0007623]; lipid metabolic process [GO:0006629]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; protein lipidation [GO:0006497]; response to calcium ion [GO:0051592]; triglyceride metabolic process [GO:0006641]; triglyceride transport [GO:0034197] comp131093_c3_seq2,343,40.8163,0.51852293,12,16,,5.00E-15,O08601,Microsomal triglyceride transfer protein large subunit,Microsomal triglyceride transfer protein large subunit,GO:0005794; GO:0042632; GO:0008203; GO:0005783; GO:0008289; GO:0005319; GO:0042953; GO:0006497; GO:0006641,Golgi apparatus; cholesterol homeostasis; cholesterol metabolic process; endoplasmic reticulum; lipid binding; lipid transporter activity; lipoprotein transport; protein lipidation; triglyceride metabolic process,PF01347;,,,,,,,,,MTP_MOUSE,Mus musculus (Mouse),cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; circadian rhythm [GO:0007623]; lipid metabolic process [GO:0006629]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; protein lipidation [GO:0006497]; response to calcium ion [GO:0051592]; triglyceride metabolic process [GO:0006641]; triglyceride transport [GO:0034197] comp131102_c1_seq1,843,41.1625,0.42652172,38,37,,2.00E-18,P51784,Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11),Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11),GO:0004197; GO:0005737; GO:0005634; GO:0016579; GO:0004221; GO:0006511; GO:0004843,cysteine-type endopeptidase activity; cytoplasm; nucleus; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;PF14533;,3.00E-22,CHOYP_LOC100369578.1.1,,,,,,,UBP11_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp131107_c0_seq1,979,42.9009,0.50051125,0,0,,3.00E-13,P42837,"Polyphosphoinositide phosphatase (EC 3.1.3.-) (Factor-induced gene 4 protein) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase)","Polyphosphoinositide phosphatase (EC 3.1.3.-) (Factor-induced gene 4 protein) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase)",GO:0070772; GO:0019898; GO:0000329; GO:0046856; GO:0043813,"PAS complex; extrinsic to membrane; fungal-type vacuole membrane; phosphatidylinositol dephosphorylation; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity",PF02383;,,,,,,,,,FIG4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),phosphatidylinositol dephosphorylation [GO:0046856] comp131107_c0_seq2,2062,44.1319,0.57910639,2,0,,0,A8E7C5,Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.-) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 5-phosphatase 2),Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.25) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 4-phosphatase 2) (hSAC2),GO:0042578,phosphoric ester hydrolase activity,PF12456;PF02383;,,,,,,,,,SAC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),clathrin-mediated endocytosis [GO:0072583]; regulation of endocytic recycling [GO:2001135] comp131107_c0_seq4,1137,44.9428,0.65561212,0,6,,,,,,,,,9.00E-138,CHOYP_LOC663138.1.1,,,,,,,,, comp131111_c0_seq1,1148,40.1568,1.18725693,19,2456,female>male,4.00E-39,P18426,S-crystallin SL11 (Major lens polypeptide),S-crystallin SL11 (Major lens polypeptide),GO:0005212,structural constituent of eye lens,PF14497;PF02798;,,,,,,,,,SCR11_OMMSL,Nototodarus sloanii (Wellington flying squid) (Ommastrephes sloanei), comp131113_c4_seq1,1237,36.8634,1.0741769,30,232,,1.00E-11,P82147,Protein lethal(2)essential for life (Protein Efl21),Protein lethal(2)essential for life (Protein Efl21),GO:0007275; GO:0010998,multicellular organismal development; regulation of translational initiation by eIF2 alpha phosphorylation,PF00011;,7.00E-13,CHOYP_CG14207.1.1,3.00E-91,ruditapes_c4169,,,,,L2EFL_DROME,Drosophila melanogaster (Fruit fly),multicellular organism development [GO:0007275]; protein refolding [GO:0042026]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to heat [GO:0009408]; sarcomere organization [GO:0045214] comp131113_c5_seq1,1950,37.5385,0.75918962,1571,386,,1.00E-19,Q5SV06,Spermatogenesis-associated protein 22,Spermatogenesis-associated protein 22,GO:0009566; GO:0007276; GO:0000711; GO:0051445; GO:0061458; GO:0007129,fertilization; gamete generation; meiotic DNA repair synthesis; regulation of meiotic cell cycle; reproductive system development; synapsis,,,,,,,,,,SPT22_MOUSE,Mus musculus (Mouse),fertilization [GO:0009566]; gamete generation [GO:0007276]; meiotic DNA repair synthesis [GO:0000711]; regulation of meiotic cell cycle [GO:0051445]; reproductive system development [GO:0061458]; synapsis [GO:0007129] comp131115_c0_seq4,2033,43.8269,0.43400479,0,0,,9.00E-14,Q8VC31,Coiled-coil domain-containing protein 9,Coiled-coil domain-containing protein 9,,,PF15266;,,,,,,,,,CCDC9_MOUSE,Mus musculus (Mouse), comp131115_c0_seq6,1952,43.4939,0.37956156,0,0,,1.00E-13,Q8VC31,Coiled-coil domain-containing protein 9,Coiled-coil domain-containing protein 9,,,PF15266;,,,,,,,,,CCDC9_MOUSE,Mus musculus (Mouse), comp131116_c0_seq1,1835,30.7357,0.5194446,2709,15490,,3.00E-48,Q5RA42,"Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)","Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)",GO:0003743,translation initiation factor activity,PF01176;,6.00E-98,CHOYP_LOC100533384.5.5,8.00E-126,ruditapes_c2098,,,,,IF1AX_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp131119_c1_seq1,1033,37.3669,0.39243151,62,57,,1.00E-92,Q99LU8,Uncharacterized protein C6orf62 homolog,Uncharacterized protein C6orf62 homolog,GO:0005622,intracellular,PF15130;,5.00E-52,CHOYP_CF062.1.1,,,,,,,CF062_MOUSE,Mus musculus (Mouse), comp131120_c1_seq2,1010,37.1287,0.7011913,10,36,,8.00E-68,O19071,"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II)","Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II)",GO:0000139; GO:0005795; GO:0008455; GO:0016021; GO:0009312; GO:0018279,"Golgi membrane; Golgi stack; alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity; integral to membrane; oligosaccharide biosynthetic process; protein N-linked glycosylation via asparagine",PF05060;,7.00E-69,CHOYP_LOC101165022.1.1,,,,,,,MGAT2_PIG,Sus scrofa (Pig),oligosaccharide biosynthetic process [GO:0009312]; protein N-linked glycosylation via asparagine [GO:0018279] comp131123_c0_seq1,1992,34.739,0.58315792,6,74,,3.00E-70,Q3ZCX4,Zinc finger protein 568,Zinc finger protein 568,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN568_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131123_c0_seq3,1859,35.0726,0.6135318,0,14,,3.00E-49,Q9BR84,Zinc finger protein 559,Zinc finger protein 559,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN559_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131139_c0_seq2,2630,43.5361,0.4428534,0,0,,7.00E-133,Q9BUJ2,Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5),Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5),GO:0003723; GO:0000398; GO:0005654; GO:0006355; GO:0009615; GO:0030529; GO:0006351,"RNA binding; mRNA splicing, via spliceosome; nucleoplasm; regulation of transcription, DNA-dependent; response to virus; ribonucleoprotein complex; transcription, DNA-dependent",PF02037;PF00622;,,,,,,,,,HNRL1_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; response to virus [GO:0009615]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]" comp131139_c0_seq3,1828,42.3414,0.47109173,0,0,,4.00E-15,Q91VR5,ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1),ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1),GO:0005524; GO:0008026; GO:0003677; GO:0032508; GO:0033677; GO:0003682; GO:0071920; GO:0010494; GO:0006302; GO:0003725; GO:0004527; GO:0006397; GO:0007275; GO:0004518; GO:0008143; GO:0006355; GO:0043330; GO:0009615; GO:0072669; GO:0003712; GO:0006351,"ATP binding; ATP-dependent helicase activity; DNA binding; DNA duplex unwinding; DNA/RNA helicase activity; chromatin binding; cleavage body; cytoplasmic stress granule; double-strand break repair; double-stranded RNA binding; exonuclease activity; mRNA processing; multicellular organismal development; nuclease activity; poly(A) RNA binding; regulation of transcription, DNA-dependent; response to exogenous dsRNA; response to virus; tRNA-splicing ligase complex; transcription cofactor activity; transcription, DNA-dependent",PF00270;PF00271;PF00622;,1.00E-23,CHOYP_LOC100553519.1.1,,,,,,,DDX1_MOUSE,Mus musculus (Mouse),"DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of transcription, DNA-templated [GO:0006355]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp131139_c0_seq4,1510,44.106,0.49807574,0,0,,1.00E-135,Q8VDM6,Heterogeneous nuclear ribonucleoprotein U-like protein 1,Heterogeneous nuclear ribonucleoprotein U-like protein 1,GO:0003723; GO:0005634; GO:0006355; GO:0030529; GO:0006351,"RNA binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF02037;PF00622;,3.00E-113,CHOYP_LOC578672.1.2,,,,,,,HNRL1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; response to virus [GO:0009615]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]" comp131139_c0_seq6,2666,43.4734,0.43801252,0,0,,,,,,,,,6.00E-113,CHOYP_LOC578672.1.2,,,,,,,,, comp131146_c0_seq1,1155,40,0.17589453,11,66,,1.00E-110,Q9H477,Ribokinase (EC 2.7.1.15),Ribokinase (RK) (EC 2.7.1.15),GO:0005524; GO:0019303; GO:0004747,ATP binding; D-ribose catabolic process; ribokinase activity,PF00294;,,,9.00E-22,ruditapes_c15167,,,,,RBSK_HUMAN,Homo sapiens (Human),D-ribose catabolic process [GO:0019303] comp131148_c3_seq1,895,41.3408,0.44800056,17,60,,7.00E-10,Q9WU00,Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal),Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal),GO:0003677; GO:0007005; GO:0005634; GO:0003700; GO:0005667; GO:0006351,"DNA binding; mitochondrion organization; nucleus; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF10492;PF10491;,,,,,,,,,NRF1_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp131156_c0_seq3,1687,40.0711,0.31469064,139,907,,4.00E-96,Q6GPQ4,SET and MYND domain-containing protein 5 (EC 2.1.1.-),SET and MYND domain-containing protein 5 (EC 2.1.1.-),GO:0046872; GO:0008168,metal ion binding; methyltransferase activity,PF00856;PF01753;,2.00E-47,CHOYP_SMYD5.1.1,,,,,,,SMYD5_XENLA,Xenopus laevis (African clawed frog), comp131161_c1_seq2,735,41.0884,0.26332786,5,65,,6.00E-91,Q14376,UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase),UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase),GO:0003978; GO:0044237; GO:0050662; GO:0005829; GO:0019388; GO:0044281,UDP-glucose 4-epimerase activity; cellular metabolic process; coenzyme binding; cytosol; galactose catabolic process; small molecule metabolic process,PF16363;,3.00E-15,CHOYP_LOC100370520.1.1,,,,,,,GALE_HUMAN,Homo sapiens (Human),galactose catabolic process [GO:0019388] comp131161_c2_seq1,487,34.9076,0.2158028,3,73,,4.00E-29,P55180,UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase),UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase),GO:0003978; GO:0044237; GO:0050662; GO:0006012,UDP-glucose 4-epimerase activity; cellular metabolic process; coenzyme binding; galactose metabolic process,PF16363;,,,,,,,,,GALE_BACSU,Bacillus subtilis (strain 168),galactose metabolic process [GO:0006012] comp131167_c0_seq2,1347,34.2984,0.54954216,116,655,,,,,,,,,6.00E-90,CHOYP_LOC100181343.1.1,,,,,,,,, comp131167_c0_seq4,1331,34.4853,0.49756241,41,340,,2.00E-53,Q9VRV7,Pre-mRNA branch site p14-like protein,Splicing factor 3B subunit 6-like protein (Pre-mRNA branch site p14-like protein),GO:0071013; GO:0003729; GO:0000398; GO:0007052; GO:0048812; GO:0000166; GO:0071011,"catalytic step 2 spliceosome; mRNA binding; mRNA splicing, via spliceosome; mitotic spindle organization; neuron projection morphogenesis; nucleotide binding; precatalytic spliceosome",PF00076;,3.00E-81,CHOYP_PM14.1.1,4.00E-109,ruditapes2_c697,,,,,PM14_DROME,Drosophila melanogaster (Fruit fly),"mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; neuron projection morphogenesis [GO:0048812]" comp131170_c0_seq1,1063,35.6538,0.50854746,30,56,,4.00E-65,Q5R4C3,Transmembrane protein 50B,Transmembrane protein 50B,GO:0016021,integral to membrane,PF05255;,4.00E-60,CHOYP_TM50B.1.1,,,,,,,TM50B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp131178_c1_seq2,1017,44.4444,0.71757588,0,36,,2.00E-09,F4KD71,Urea-proton symporter DUR3 (AtDUR3) (High-affinity urea active transporter DUR3),Urea-proton symporter DUR3 (AtDUR3) (High-affinity urea active transporter DUR3),GO:0016021; GO:0005886; GO:0015293; GO:0015204,integral to membrane; plasma membrane; symporter activity; urea transmembrane transporter activity,PF00474;,,,,,,,,,DUR3_ARATH,Arabidopsis thaliana (Mouse-ear cress),urea transmembrane transport [GO:0071918] comp131179_c0_seq1,1784,43.778,0.66300562,148,368,,6.00E-59,Q9Y3M9,Zinc finger protein 337,Zinc finger protein 337,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN337_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131196_c2_seq1,2005,42.394,0.41301934,130,134,,4.00E-133,Q6QI06,Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo),Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo),GO:0031929; GO:0031932; GO:0031532; GO:0009790; GO:0032008; GO:0030838; GO:0050731; GO:0032314; GO:0030334; GO:0051896; GO:0043022,TOR signaling cascade; TORC2 complex; actin cytoskeleton reorganization; embryo development; positive regulation of TOR signaling cascade; positive regulation of actin filament polymerization; positive regulation of peptidyl-tyrosine phosphorylation; regulation of Rac GTPase activity; regulation of cell migration; regulation of protein kinase B signaling cascade; ribosome binding,PF14663;PF14666;PF14664;PF14665;PF14668;,1.00E-57,CHOYP_LOC100367446.1.1,,,,,,,RICTR_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp131198_c0_seq1,863,44.7277,0.32941221,0,14,,2.00E-98,A2VDS1,Selenocysteine lyase (EC 4.4.1.16),Selenocysteine lyase (EC 4.4.1.16),GO:0005829; GO:0030170; GO:0009000; GO:0016740,cytosol; pyridoxal phosphate binding; selenocysteine lyase activity; transferase activity,PF00266;,3.00E-15,CHOYP_SCLY.1.3,,,,,,,SCLY_BOVIN,Bos taurus (Bovine), comp131198_c0_seq2,1227,42.7058,0.35912757,0,0,,5.00E-55,A5I4Z9,Cysteine desulfurase (EC 2.8.1.7),Cysteine desulfurase IscS (EC 2.8.1.7),GO:0031071; GO:0006534; GO:0030170,cysteine desulfurase activity; cysteine metabolic process; pyridoxal phosphate binding,PF00266;,,,,,,,,,ISCS_CLOBH,Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A),[2Fe-2S] cluster assembly [GO:0044571]; cellular amino acid metabolic process [GO:0006520] comp131198_c0_seq3,1311,42.7155,0.33717125,0,0,,4.00E-140,Q9JLI6,Selenocysteine lyase (mSCL) (EC 4.4.1.16),Selenocysteine lyase (mSCL) (EC 4.4.1.16),GO:0005829; GO:0030170; GO:0009000; GO:0016740,cytosol; pyridoxal phosphate binding; selenocysteine lyase activity; transferase activity,PF00266;,4.00E-29,CHOYP_SCLY.3.3,,,,,,,SCLY_MOUSE,Mus musculus (Mouse),lipid metabolic process [GO:0006629]; negative regulation of cellular response to oxidative stress [GO:1900408]; response to insulin [GO:0032868]; selenium compound metabolic process [GO:0001887] comp131198_c0_seq4,930,44.7312,0.32495675,0,0,,4.00E-12,A8GDU4,Cysteine desulfurase (EC 2.8.1.7) (Selenocysteine beta-lyase) (SCL) (Selenocysteine lyase) (EC 4.4.1.16) (Selenocysteine reductase),Cysteine desulfurase (EC 2.8.1.7) (Selenocysteine beta-lyase) (SCL) (Selenocysteine lyase) (EC 4.4.1.16) (Selenocysteine reductase),GO:0031071; GO:0006534; GO:0005737; GO:0030170; GO:0009000,cysteine desulfurase activity; cysteine metabolic process; cytoplasm; pyridoxal phosphate binding; selenocysteine lyase activity,PF00266;,,,,,,,,,SUFS_SERP5,Serratia proteamaculans (strain 568),cysteine metabolic process [GO:0006534] comp131198_c0_seq5,1014,44.5759,0.30177826,0,0,,5.00E-18,P57989,Probable cysteine desulfurase (EC 2.8.1.7),Probable cysteine desulfurase (EC 2.8.1.7),GO:0031071; GO:0030170,cysteine desulfurase activity; pyridoxal phosphate binding,PF00266;,2.00E-24,CHOYP_SCLY.3.3,,,,,,,CSD_PASMU,Pasteurella multocida (strain Pm70), comp131199_c1_seq1,839,47.199,0.81553514,44,103,,2.00E-40,Q2EJA0,Yorkie homolog (65 kDa Yes-associated protein) (YAP65),Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog),GO:0006975; GO:0071480; GO:0005737; GO:0005634; GO:0006355; GO:0044212; GO:0006351,"DNA damage induced protein phosphorylation; cellular response to gamma radiation; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00397;,,,,,,,,,YAP1_RAT,Rattus norvegicus (Rat),"bud elongation involved in lung branching [GO:0060449]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; DNA damage induced protein phosphorylation [GO:0006975]; embryonic heart tube morphogenesis [GO:0003143]; hippo signaling [GO:0035329]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of stem cell differentiation [GO:2000737]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]" comp131199_c1_seq2,567,43.2099,0.60683949,2,0,,,,,,,,,2.00E-23,CHOYP_YAP.2.2,,,,,,,,, comp131202_c0_seq1,775,37.9355,0.90197748,9,131,,9.00E-09,Q9NZT1,Calmodulin-like protein 5 (Calmodulin-like skin protein),Calmodulin-like protein 5 (Calmodulin-like skin protein),GO:0005509; GO:0008544; GO:0007165,calcium ion binding; epidermis development; signal transduction,PF13499;,,,,,,,,,CALL5_HUMAN,Homo sapiens (Human),epidermis development [GO:0008544]; signal transduction [GO:0007165] comp131203_c0_seq1,525,48.1905,0.65972897,34,0,,1.00E-42,Q9JLB4,Cubilin (Intrinsic factor-cobalamin receptor),Cubilin (Intrinsic factor-cobalamin receptor),GO:0005794; GO:0016324; GO:0005903; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0030139; GO:0005783; GO:0005768; GO:0010008; GO:0042953; GO:0005765; GO:0004872; GO:0006898,Golgi apparatus; apical plasma membrane; brush border; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; endocytic vesicle; endoplasmic reticulum; endosome; endosome membrane; lipoprotein transport; lysosomal membrane; receptor activity; receptor-mediated endocytosis,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898] comp131203_c1_seq1,488,47.7459,0.58033176,25,0,,8.00E-18,Q9BY79,Membrane frizzled-related protein (Membrane-type frizzled-related protein),Membrane frizzled-related protein (Membrane-type frizzled-related protein),GO:0009790; GO:0016021,embryo development; integral to membrane,PF00431;PF01392;PF00057;,,,,,,,,,MFRP_HUMAN,Homo sapiens (Human),embryo development [GO:0009790]; eye photoreceptor cell development [GO:0042462]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601] comp131203_c2_seq2,460,43.6957,0.36777198,11,13,,3.00E-31,P98070,Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-),Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-),GO:0005794; GO:0005509; GO:0051216; GO:0030154; GO:0005615; GO:0004222; GO:0001503; GO:0005578; GO:0006508; GO:0008270,Golgi apparatus; calcium ion binding; cartilage development; cell differentiation; extracellular space; metalloendopeptidase activity; ossification; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF01400;PF00431;,,,,,,,,,BMP1_XENLA,Xenopus laevis (African clawed frog),cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] comp131204_c0_seq4,1008,39.2857,0.3370683,26,41,,2.00E-11,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131211_c0_seq2,1223,37.776,0.50969144,18,100,,5.00E-95,Q9D7M1,Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1),Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1),GO:0005634,nucleus,PF10607;PF08513;,9.00E-88,CHOYP_LOC100376325.2.2,,,,,,,GID8_MOUSE,Mus musculus (Mouse), comp131213_c0_seq1,709,38.5049,0.68636012,147,1519,,5.00E-36,Q6GM07,Cyclin-dependent kinase 2-interacting protein,Cyclin-dependent kinase 2-interacting protein,GO:0006281; GO:0006260; GO:0007049; GO:0051301; GO:0005634,DNA repair; DNA replication; cell cycle; cell division; nucleus,,6.00E-11,CHOYP_CINP.1.1,,,,,,,CINP_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp131218_c0_seq2,1355,43.3948,0.36571314,68,198,,3.00E-140,Q5R6S0,Abhydrolase domain-containing protein 16A (EC 3.-.-.-) (HLA-B-associated transcript 5),Protein ABHD16A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5),GO:0016787; GO:0016021,hydrolase activity; integral to membrane,PF00561;,,,,,,,,,ABHGA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp131222_c0_seq1,1062,45.951,1.02108281,62,38,,4.00E-51,Q5R9C2,Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3),Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3),GO:0005887; GO:0015820; GO:0005328; GO:0005298,integral to plasma membrane; leucine transport; neurotransmitter:sodium symporter activity; proline:sodium symporter activity,PF00209;,3.00E-55,CHOYP_S620B.1.1,,,,,,,S6A15_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824] comp131223_c0_seq1,893,45.6887,1.01004934,91,186,,,,,,,,,8.00E-17,CHOYP_contig_054902,1.00E-44,ruditapes_c1595,,,,,,, comp131226_c0_seq2,602,46.3455,0.86771747,30,52,,6.00E-13,P16109,P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P),P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P),GO:0050829; GO:0009897; GO:0005615; GO:0042806; GO:0043208; GO:0008201; GO:0007157; GO:0006954; GO:0005887; GO:0007159; GO:0050900; GO:0050901; GO:0001530; GO:0005634; GO:0070492; GO:0030168; GO:0031092; GO:0002576; GO:0031088; GO:0002687; GO:0014068; GO:0010572; GO:0033623; GO:0032496; GO:0033691,defense response to Gram-negative bacterium; external side of plasma membrane; extracellular space; fucose binding; glycosphingolipid binding; heparin binding; heterophilic cell-cell adhesion; inflammatory response; integral to plasma membrane; leukocyte cell-cell adhesion; leukocyte migration; leukocyte tethering or rolling; lipopolysaccharide binding; nucleus; oligosaccharide binding; platelet activation; platelet alpha granule membrane; platelet degranulation; platelet dense granule membrane; positive regulation of leukocyte migration; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of platelet activation; regulation of integrin activation; response to lipopolysaccharide; sialic acid binding,PF00059;PF00084;,,,,,,,,,LYAM3_HUMAN,Homo sapiens (Human),calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of cell adhesion [GO:0045785]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of cellular extravasation [GO:0002691]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070] comp131226_c1_seq4,794,42.6952,0.90195576,0,0,,9.00E-14,Q80T79,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_MOUSE,Mus musculus (Mouse), comp131230_c1_seq2,874,38.7872,0.53281107,10,12,,4.00E-29,Q7TN79,A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma),A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma),GO:0003824; GO:0005737; GO:0008152; GO:0000166; GO:0005634; GO:0034237; GO:0019901; GO:0008104; GO:0007178,catalytic activity; cytoplasm; metabolic process; nucleotide binding; nucleus; protein kinase A regulatory subunit binding; protein kinase binding; protein localization; transmembrane receptor protein serine/threonine kinase signaling pathway,PF10469;PF10470;,,,,,,,,,AKA7G_MOUSE,Mus musculus (Mouse),cellular response to cAMP [GO:0071320]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of potassium ion transmembrane transport [GO:1901381]; protein localization [GO:0008104]; regulation of membrane repolarization [GO:0060306]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] comp131230_c1_seq3,700,38.2857,0.48145703,0,2,,2.00E-21,Q7TN79,A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma),A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma),GO:0003824; GO:0005737; GO:0008152; GO:0000166; GO:0005634; GO:0034237; GO:0019901; GO:0008104; GO:0007178,catalytic activity; cytoplasm; metabolic process; nucleotide binding; nucleus; protein kinase A regulatory subunit binding; protein kinase binding; protein localization; transmembrane receptor protein serine/threonine kinase signaling pathway,PF10469;PF10470;,,,,,,,,,AKA7G_MOUSE,Mus musculus (Mouse),cellular response to cAMP [GO:0071320]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of potassium ion transmembrane transport [GO:1901381]; protein localization [GO:0008104]; regulation of membrane repolarization [GO:0060306]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] comp131234_c1_seq1,1099,36.2147,0.19642372,104,333,,2.00E-33,Q6NXR4,TELO2-interacting protein 2,TELO2-interacting protein 2,,,PF10521;,,,4.00E-19,ruditapes_c11574,,,,,TTI2_HUMAN,Homo sapiens (Human), comp131235_c0_seq2,1220,44.4262,0.33452077,37,33,,8.00E-111,P49815,Tuberin (Tuberous sclerosis 2 protein),Tuberin (Tuberous sclerosis 2 protein),GO:0038095; GO:0005096; GO:0005794; GO:0033596; GO:0006953; GO:0005901; GO:0007050; GO:0030030; GO:0030425; GO:0006897; GO:0007173; GO:0008543; GO:0030426; GO:0007507; GO:0045087; GO:0008286; GO:0048009; GO:0016020; GO:0043407; GO:0032007; GO:0030178; GO:0008285; GO:0045792; GO:0050680; GO:0014067; GO:0051898; GO:0006469; GO:0001843; GO:0043025; GO:0048011; GO:0005634; GO:0048471; GO:0019902; GO:0014065; GO:0048015; GO:0050918; GO:0051291; GO:0051260; GO:0006606; GO:0043491; GO:0030100; GO:0046626; GO:0051056; GO:0001666,Fc-epsilon receptor signaling pathway; GTPase activator activity; Golgi apparatus; TSC1-TSC2 complex; acute-phase response; caveola; cell cycle arrest; cell projection organization; dendrite; endocytosis; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; growth cone; heart development; innate immune response; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; membrane; negative regulation of MAP kinase activity; negative regulation of TOR signaling cascade; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of epithelial cell proliferation; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of protein kinase B signaling cascade; negative regulation of protein kinase activity; neural tube closure; neuronal cell body; neurotrophin TRK receptor signaling pathway; nucleus; perinuclear region of cytoplasm; phosphatase binding; phosphatidylinositol 3-kinase cascade; phosphatidylinositol-mediated signaling; positive chemotaxis; protein heterooligomerization; protein homooligomerization; protein import into nucleus; protein kinase B signaling cascade; regulation of endocytosis; regulation of insulin receptor signaling pathway; regulation of small GTPase mediated signal transduction; response to hypoxia,PF11864;PF02145;PF03542;,,,,,,,,,TSC2_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032] comp131235_c2_seq1,1040,42.8846,0.46061989,55,71,,2.00E-86,P49815,Tuberin (Tuberous sclerosis 2 protein),Tuberin (Tuberous sclerosis 2 protein),GO:0038095; GO:0005096; GO:0005794; GO:0033596; GO:0006953; GO:0005901; GO:0007050; GO:0030030; GO:0030425; GO:0006897; GO:0007173; GO:0008543; GO:0030426; GO:0007507; GO:0045087; GO:0008286; GO:0048009; GO:0016020; GO:0043407; GO:0032007; GO:0030178; GO:0008285; GO:0045792; GO:0050680; GO:0014067; GO:0051898; GO:0006469; GO:0001843; GO:0043025; GO:0048011; GO:0005634; GO:0048471; GO:0019902; GO:0014065; GO:0048015; GO:0050918; GO:0051291; GO:0051260; GO:0006606; GO:0043491; GO:0030100; GO:0046626; GO:0051056; GO:0001666,Fc-epsilon receptor signaling pathway; GTPase activator activity; Golgi apparatus; TSC1-TSC2 complex; acute-phase response; caveola; cell cycle arrest; cell projection organization; dendrite; endocytosis; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; growth cone; heart development; innate immune response; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; membrane; negative regulation of MAP kinase activity; negative regulation of TOR signaling cascade; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of epithelial cell proliferation; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of protein kinase B signaling cascade; negative regulation of protein kinase activity; neural tube closure; neuronal cell body; neurotrophin TRK receptor signaling pathway; nucleus; perinuclear region of cytoplasm; phosphatase binding; phosphatidylinositol 3-kinase cascade; phosphatidylinositol-mediated signaling; positive chemotaxis; protein heterooligomerization; protein homooligomerization; protein import into nucleus; protein kinase B signaling cascade; regulation of endocytosis; regulation of insulin receptor signaling pathway; regulation of small GTPase mediated signal transduction; response to hypoxia,PF11864;PF02145;PF03542;,5.00E-103,CHOYP_LOC101078033.1.1,,,,,,,TSC2_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032] comp13123_c0_seq1,337,32.6409,1.02218642,6,0,,,,,,,,,,,4.00E-20,ruditapes_c13109,,,,,,, comp131241_c0_seq1,356,37.9213,0.31357296,0,0,,8.00E-10,O75362,Zinc finger protein 217,Zinc finger protein 217,GO:0000118; GO:0046872; GO:0045892; GO:0003700; GO:0044212; GO:0006351,"histone deacetylase complex; metal ion binding; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",,,,,,,,,,ZN217_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp131241_c0_seq2,393,38.1679,0.42146823,0,0,,2.00E-16,Q29419,Zinc finger Y-chromosomal protein (Fragment),Zinc finger Y-chromosomal protein (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZFY_PIG,Sus scrofa (Pig),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131241_c0_seq3,207,45.4106,0.2829998,0,0,,1.00E-06,Q9BRR0,Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47),Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47),GO:0006914; GO:0003682; GO:0005737; GO:0007040; GO:0046872; GO:0010507; GO:2000773; GO:0045892; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"autophagy; chromatin binding; cytoplasm; lysosome organization; metal ion binding; negative regulation of autophagy; negative regulation of cellular senescence; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;,,,,,,,,,ZKSC3_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; negative regulation of cellular senescence [GO:2000773]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp131247_c0_seq1,245,40,0.41607458,8,3,,5.00E-17,Q6P1X5,Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),GO:0000086; GO:0008237; GO:0045944; GO:0005669; GO:0033276; GO:0006367; GO:0044212; GO:0008270,G2/M transition of mitotic cell cycle; metallopeptidase activity; positive regulation of transcription from RNA polymerase II promoter; transcription factor TFIID complex; transcription factor TFTC complex; transcription initiation from RNA polymerase II promoter; transcription regulatory region DNA binding; zinc ion binding,PF01433;,,,,,,,,,TAF2_HUMAN,Homo sapiens (Human),G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to organic cyclic compound [GO:0014070]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp131252_c2_seq2,904,46.1283,0.63457956,11,45,,2.00E-81,O94762,"ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)","ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)",GO:0005524; GO:0008026; GO:0003678; GO:0006310; GO:0006281; GO:0006260; GO:0016591; GO:0000993; GO:0051301; GO:0051304; GO:0005737; GO:0007067; GO:0034244; GO:0031965; GO:0003676; GO:0005730,"ATP binding; ATP-dependent helicase activity; DNA helicase activity; DNA recombination; DNA repair; DNA replication; DNA-directed RNA polymerase II, holoenzyme; RNA polymerase II core binding; cell division; chromosome separation; cytoplasm; mitosis; negative regulation of transcription elongation from RNA polymerase II promoter; nuclear membrane; nucleic acid binding; nucleolus",PF00270;PF00271;PF06959;PF16124;,6.00E-38,CHOYP_RECQL5.1.1,,,,,,,RECQ5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244] comp131256_c0_seq1,1063,42.0508,0.63022932,74,76,,3.00E-36,O02194,Presenilin homolog (DmPS) (EC 3.4.23.-) (dPS),Presenilin homolog (DmPS) (EC 3.4.23.-) (dPS),GO:0000139; GO:0007220; GO:0007219; GO:0030018; GO:0042987; GO:0016324; GO:0004190; GO:0030424; GO:0050435; GO:0006816; GO:0005938; GO:0009986; GO:0016337; GO:0035253; GO:0015677; GO:0007010; GO:0043198; GO:0004175; GO:0005789; GO:0030426; GO:0005887; GO:0046331; GO:0005765; GO:0006509; GO:0045121; GO:0005743; GO:0031594; GO:0048812; GO:0043025; GO:0005634; GO:0048471; GO:0008593; GO:0048190,Golgi membrane; Notch receptor processing; Notch signaling pathway; Z disc; amyloid precursor protein catabolic process; apical plasma membrane; aspartic-type endopeptidase activity; axon; beta-amyloid metabolic process; calcium ion transport; cell cortex; cell surface; cell-cell adhesion; ciliary rootlet; copper ion import; cytoskeleton organization; dendritic shaft; endopeptidase activity; endoplasmic reticulum membrane; growth cone; integral to plasma membrane; lateral inhibition; lysosomal membrane; membrane protein ectodomain proteolysis; membrane raft; mitochondrial inner membrane; neuromuscular junction; neuron projection morphogenesis; neuronal cell body; nucleus; perinuclear region of cytoplasm; regulation of Notch signaling pathway; wing disc dorsal/ventral pattern formation,PF01080;,,,5.00E-63,ruditapes_c12256,,,,,PSN_DROME,Drosophila melanogaster (Fruit fly),amyloid precursor protein catabolic process [GO:0042987]; apoptotic process [GO:0006915]; beta-amyloid metabolic process [GO:0050435]; calcium ion transport [GO:0006816]; copper ion import [GO:0015677]; cytoskeleton organization [GO:0007010]; lateral inhibition [GO:0046331]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of apoptotic process [GO:0043066]; neuron projection morphogenesis [GO:0048812]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; protein processing [GO:0016485]; regulation of heart rate [GO:0002027]; regulation of Notch signaling pathway [GO:0008593]; single organismal cell-cell adhesion [GO:0016337]; wing disc dorsal/ventral pattern formation [GO:0048190] comp131256_c2_seq1,747,43.909,0.61700084,52,58,,2.00E-45,Q4JIM4,Presenilin-1 (PS-1) (EC 3.4.23.-) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit],Presenilin-1 (PS-1) (EC 3.4.23.-) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit],GO:0021870; GO:0005794; GO:0000139; GO:0015813; GO:0007220; GO:0007219; GO:0002286; GO:0050852; GO:0030018; GO:0000186; GO:0042987; GO:0042640; GO:0016324; GO:0004190; GO:0000045; GO:0030424; GO:0034205; GO:0050435; GO:0001568; GO:0048854; GO:0045296; GO:0005262; GO:0006816; GO:0005938; GO:0001708; GO:0009986; GO:0016337; GO:0005813; GO:0021795; GO:0015871; GO:0035253; GO:0031410; GO:0043198; GO:0021904; GO:0030326; GO:0004175; GO:0005783; GO:0005789; GO:0050673; GO:0070765; GO:0030426; GO:0001947; GO:0002244; GO:0005887; GO:0035556; GO:0000776; GO:0005765; GO:0006509; GO:0045121; GO:0007613; GO:0005743; GO:0006839; GO:0002573; GO:0043066; GO:0050771; GO:0007175; GO:2000059; GO:0000122; GO:0051444; GO:0031594; GO:0051402; GO:0048666; GO:0001764; GO:0043025; GO:0005640; GO:0005634; GO:0048471; GO:0043406; GO:0043065; GO:0043085; GO:0050820; GO:0032436; GO:0001921; GO:0009791; GO:0006486; GO:0016485; GO:0015031; GO:0042325; GO:0043393; GO:0060075; GO:0048167; GO:0051966; GO:0006974; GO:0006979; GO:0005791; GO:0048705; GO:0043589; GO:0005790; GO:0051563; GO:0001756; GO:0016080; GO:0048538,"Cajal-Retzius cell differentiation; Golgi apparatus; Golgi membrane; L-glutamate transport; Notch receptor processing; Notch signaling pathway; T cell activation involved in immune response; T cell receptor signaling pathway; Z disc; activation of MAPKK activity; amyloid precursor protein catabolic process; anagen; apical plasma membrane; aspartic-type endopeptidase activity; autophagic vacuole assembly; axon; beta-amyloid formation; beta-amyloid metabolic process; blood vessel development; brain morphogenesis; cadherin binding; calcium channel activity; calcium ion transport; cell cortex; cell fate specification; cell surface; cell-cell adhesion; centrosome; cerebral cortex cell migration; choline transport; ciliary rootlet; cytoplasmic vesicle; dendritic shaft; dorsal/ventral neural tube patterning; embryonic limb morphogenesis; endopeptidase activity; endoplasmic reticulum; endoplasmic reticulum membrane; epithelial cell proliferation; gamma-secretase complex; growth cone; heart looping; hematopoietic progenitor cell differentiation; integral to plasma membrane; intracellular signal transduction; kinetochore; lysosomal membrane; membrane protein ectodomain proteolysis; membrane raft; memory; mitochondrial inner membrane; mitochondrial transport; myeloid leukocyte differentiation; negative regulation of apoptotic process; negative regulation of axonogenesis; negative regulation of epidermal growth factor-activated receptor activity; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of ubiquitin-protein ligase activity; neuromuscular junction; neuron apoptotic process; neuron development; neuron migration; neuronal cell body; nuclear outer membrane; nucleus; perinuclear region of cytoplasm; positive regulation of MAP kinase activity; positive regulation of apoptotic process; positive regulation of catalytic activity; positive regulation of coagulation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of receptor recycling; post-embryonic development; protein glycosylation; protein processing; protein transport; regulation of phosphorylation; regulation of protein binding; regulation of resting membrane potential; regulation of synaptic plasticity; regulation of synaptic transmission, glutamatergic; response to DNA damage stimulus; response to oxidative stress; rough endoplasmic reticulum; skeletal system morphogenesis; skin morphogenesis; smooth endoplasmic reticulum; smooth endoplasmic reticulum calcium ion homeostasis; somitogenesis; synaptic vesicle targeting; thymus development",PF01080;,2.00E-87,CHOYP_BRAFLDRAFT_118108.1.1,,,,,,,PSN1_CHICK,Gallus gallus (Chicken),"activation of MAPKK activity [GO:0000186]; autophagosome assembly [GO:0000045]; beta-amyloid formation [GO:0034205]; blood vessel development [GO:0001568]; brain morphogenesis [GO:0048854]; Cajal-Retzius cell differentiation [GO:0021870]; canonical Wnt signaling pathway [GO:0060070]; cell fate specification [GO:0001708]; cellular response to DNA damage stimulus [GO:0006974]; cerebral cortex cell migration [GO:0021795]; choline transport [GO:0015871]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic limb morphogenesis [GO:0030326]; epithelial cell proliferation [GO:0050673]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; L-glutamate transport [GO:0015813]; membrane protein ectodomain proteolysis [GO:0006509]; memory [GO:0007613]; mitochondrial transport [GO:0006839]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of axonogenesis [GO:0050771]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; neuron migration [GO:0001764]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of coagulation [GO:0050820]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of receptor recycling [GO:0001921]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein glycosylation [GO:0006486]; protein processing [GO:0016485]; protein transport [GO:0015031]; regulation of phosphorylation [GO:0042325]; regulation of protein binding [GO:0043393]; regulation of resting membrane potential [GO:0060075]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to oxidative stress [GO:0006979]; skeletal system morphogenesis [GO:0048705]; skin morphogenesis [GO:0043589]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; somitogenesis [GO:0001756]; synaptic vesicle targeting [GO:0016080]; T cell activation involved in immune response [GO:0002286]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]" comp131256_c2_seq2,297,45.4545,0.32790865,13,20,,1.00E-37,P52166,Presenilin sel-12 (Suppressor/enhancer of lin-12 protein 12),Presenilin sel-12 (Suppressor/enhancer of lin-12 protein 12),GO:0000139; GO:0007220; GO:0007219; GO:0030018; GO:0042987; GO:0016324; GO:0045176; GO:0004190; GO:0030424; GO:0050435; GO:0006816; GO:0005938; GO:0001708; GO:0009986; GO:0035253; GO:0043198; GO:0016048; GO:0004175; GO:0005789; GO:0030426; GO:0005887; GO:0005765; GO:0006509; GO:0045121; GO:0005743; GO:0007399; GO:0031594; GO:0043025; GO:0005634; GO:0018991; GO:0048471; GO:0045747; GO:0048563; GO:0017015,Golgi membrane; Notch receptor processing; Notch signaling pathway; Z disc; amyloid precursor protein catabolic process; apical plasma membrane; apical protein localization; aspartic-type endopeptidase activity; axon; beta-amyloid metabolic process; calcium ion transport; cell cortex; cell fate specification; cell surface; ciliary rootlet; dendritic shaft; detection of temperature stimulus; endopeptidase activity; endoplasmic reticulum membrane; growth cone; integral to plasma membrane; lysosomal membrane; membrane protein ectodomain proteolysis; membrane raft; mitochondrial inner membrane; nervous system development; neuromuscular junction; neuronal cell body; nucleus; oviposition; perinuclear region of cytoplasm; positive regulation of Notch signaling pathway; post-embryonic organ morphogenesis; regulation of transforming growth factor beta receptor signaling pathway,PF01080;,,,,,,,,,PSN_CAEEL,Caenorhabditis elegans,amyloid precursor protein catabolic process [GO:0042987]; apical protein localization [GO:0045176]; beta-amyloid metabolic process [GO:0050435]; calcium ion transport [GO:0006816]; cell fate specification [GO:0001708]; detection of temperature stimulus [GO:0016048]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of Notch signaling pathway [GO:0045747]; post-embryonic organ morphogenesis [GO:0048563]; protein processing [GO:0016485]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] comp131266_c1_seq1,1506,37.583,0.4693244,68,70,,,,,,,,,1.00E-73,CHOYP_LOC100369871.1.2,,,,,,,,, comp131270_c0_seq1,1176,42.8571,0.33480326,55,188,,5.00E-30,Q6NZC7,SEC23-interacting protein,SEC23-interacting protein,GO:0012507; GO:0005783; GO:0046872,ER to Golgi transport vesicle membrane; endoplasmic reticulum; metal ion binding,PF02862;PF00536;,3.00E-23,CHOYP_SEC23IP.1.1,,,,,,,S23IP_MOUSE,Mus musculus (Mouse),acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286] comp131275_c0_seq1,2694,40.3489,0.4858887,210,262,,0,D2XV59,GTP-binding protein 1,GTP-binding protein 1,GO:0005525; GO:0003924; GO:0000177; GO:0005829; GO:0061014,GTP binding; GTPase activity; cytoplasmic exosome (RNase complex); cytosol; positive regulation of mRNA catabolic process,,0,CHOYP_GTPB1.1.1,,,,,,,GTPB1_RAT,Rattus norvegicus (Rat),positive regulation of mRNA catabolic process [GO:0061014]; translational elongation [GO:0006414] comp131279_c0_seq1,1267,38.753,0.53216525,568,2206,,2.00E-63,Q9VCX3,"Probable 39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)","Probable 39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)",GO:0005762; GO:0003735,mitochondrial large ribosomal subunit; structural constituent of ribosome,PF04280;,,,,,,,,,RM45_DROME,Drosophila melanogaster (Fruit fly), comp131281_c0_seq1,1256,37.5796,0.83800053,29,245,,2.00E-14,Q869C3,Acetylcholinesterase (AChE) (EC 3.1.1.7),Acetylcholinesterase (AChE) (EC 3.1.1.7),GO:0003990; GO:0004091; GO:0030054; GO:0019695; GO:0042135; GO:0045202; GO:0007271,"acetylcholinesterase activity; carboxylesterase activity; cell junction; choline metabolic process; neurotransmitter catabolic process; synapse; synaptic transmission, cholinergic",PF00135;,,,,,,,,,ACES_ANOGA,Anopheles gambiae (African malaria mosquito),neurotransmitter catabolic process [GO:0042135] comp131283_c1_seq1,1117,36.5264,0.70227884,83,324,,7.00E-20,Q8VD50,DNA damage-inducible transcript 4-like protein (Soleus muscle atrophied after hindlimb suspension protein 1),DNA damage-inducible transcript 4-like protein (Soleus muscle atrophied after hindlimb suspension protein 1),GO:0005737; GO:0009968,cytoplasm; negative regulation of signal transduction,PF07809;,,,,,,,,,DDT4L_RAT,Rattus norvegicus (Rat),negative regulation of signal transduction [GO:0009968] comp131284_c0_seq2,2499,45.2581,0.36774147,157,0,,2.00E-11,Q01016,Complement control protein homolog (CCPH),Complement control protein homolog (CCPH),GO:0005576; GO:0016021; GO:0045916,extracellular region; integral to membrane; negative regulation of complement activation,PF00084;,,,,,,,,,CCPH_SHV21,Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri),negative regulation of complement activation [GO:0045916] comp131284_c1_seq1,1846,48.6999,0.36757327,0,0,,4.00E-56,P98109,P-selectin (CD62 antigen-like family member P) (CD62P antigen) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62),P-selectin (CD62 antigen-like family member P) (CD62P antigen) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62),GO:0030246; GO:0007155; GO:0016021,carbohydrate binding; cell adhesion; integral to membrane,PF00059;PF00084;,,,,,,,,,LYAM3_SHEEP,Ovis aries (Sheep),cell adhesion [GO:0007155] comp131284_c1_seq2,2252,46.0036,0.41169108,3,0,,8.00E-22,P33703,Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),GO:0007597; GO:0009986; GO:0042627; GO:0031012; GO:0008201; GO:0034364; GO:0060230; GO:0016525; GO:0030195; GO:0010596; GO:0001937; GO:0051918; GO:0033033; GO:0034392; GO:0005543; GO:0031639; GO:0051006; GO:0006641; GO:0034361,"blood coagulation, intrinsic pathway; cell surface; chylomicron; extracellular matrix; heparin binding; high-density lipoprotein particle; lipoprotein lipase activator activity; negative regulation of angiogenesis; negative regulation of blood coagulation; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; negative regulation of fibrinolysis; negative regulation of myeloid cell apoptotic process; negative regulation of smooth muscle cell apoptotic process; phospholipid binding; plasminogen activation; positive regulation of lipoprotein lipase activity; triglyceride metabolic process; very-low-density lipoprotein particle",PF00084;PF09014;,,,,,,,,,APOH_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),"blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]" comp131284_c1_seq3,1016,47.6378,0.43712648,0,0,,3.00E-18,Q6VE48,Membrane cofactor protein (CD antigen CD46),Membrane cofactor protein (CD antigen CD46),GO:0006958; GO:0045087; GO:0002079; GO:0016021; GO:0007338,"complement activation, classical pathway; innate immune response; inner acrosomal membrane; integral to membrane; single fertilization",PF00084;,,,,,,,,,MCP_BOVIN,Bos taurus (Bovine),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; single fertilization [GO:0007338]" comp131284_c1_seq4,3082,47.1447,0.38603305,6,0,,5.00E-85,Q80T79,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_MOUSE,Mus musculus (Mouse), comp131284_c1_seq5,364,47.5275,0.24431242,0,0,,1.00E-18,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp131286_c0_seq1,1227,42.2983,0.42589176,77,77,,1.00E-63,Q8NEF3,Coiled-coil domain-containing protein 112 (Mutated in bladder cancer protein 1),Coiled-coil domain-containing protein 112 (Mutated in bladder cancer protein 1),,,,3.00E-62,CHOYP_CCDC112.1.1,,,,,,,CC112_HUMAN,Homo sapiens (Human), comp131288_c2_seq1,638,39.3417,0.4058699,13,65,,1.00E-73,A5PJ65,Protein RER1,Protein RER1,GO:0030173; GO:0006890,"integral to Golgi membrane; retrograde vesicle-mediated transport, Golgi to ER",PF03248;,4.00E-32,CHOYP_RER1.1.1,,,,,,,RER1_BOVIN,Bos taurus (Bovine),"retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp131289_c0_seq1,425,43.5294,0.25017757,18,14,,2.00E-38,O95544,NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase),NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase),GO:0005524; GO:0046034; GO:0019674; GO:0003951; GO:0006741; GO:0005829; GO:0046872; GO:0006767,ATP binding; ATP metabolic process; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; cytosol; metal ion binding; water-soluble vitamin metabolic process,PF01513;,1.00E-55,CHOYP_LOC100875114.1.1,,,,,,,NADK_HUMAN,Homo sapiens (Human),ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310] comp131289_c0_seq2,273,44.6886,0.51670952,3,9,,5.00E-34,Q9C5W3,"NAD kinase 2, chloroplastic (AtNADK-2) (EC 2.7.1.23)","NAD kinase 2, chloroplastic (AtNADK-2) (EC 2.7.1.23)",GO:0005524; GO:0019674; GO:0003951; GO:0006741; GO:0009507,ATP binding; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; chloroplast,PF01513;,,,7.00E-28,ruditapes_c29740,,,,,NADK2_ARATH,Arabidopsis thaliana (Mouse-ear cress),NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741] comp131292_c0_seq1,2285,41.9694,0.49758401,37,63,,4.00E-24,Q90YL3,Mediator of RNA polymerase II transcription subunit 26 (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26),Mediator of RNA polymerase II transcription subunit 26 (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26),GO:0003677; GO:0001104; GO:0016592,DNA binding; RNA polymerase II transcription cofactor activity; mediator complex,PF08711;PF15693;PF15694;,5.00E-24,CHOYP_LOC100879604.1.1,,,,,,,MED26_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp131293_c1_seq3,787,44.4727,0.80437418,9,18,,2.00E-11,Q60715,"Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)","Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)",GO:0031418; GO:0030199; GO:0005788; GO:0005506; GO:0005739; GO:0016702; GO:0018401; GO:0004656,"L-ascorbic acid binding; collagen fibril organization; endoplasmic reticulum lumen; iron ion binding; mitochondrion; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; procollagen-proline 4-dioxygenase activity",PF13640;PF08336;,,,,,,,,,P4HA1_MOUSE,Mus musculus (Mouse),collagen fibril organization [GO:0030199]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] comp131297_c1_seq1,1514,44.2536,0.66215064,121,17,,5.00E-29,Q8CIR4,Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6),Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6),GO:0005524; GO:0016324; GO:0031526; GO:0005262; GO:0005261; GO:0016021; GO:0046872; GO:0030001; GO:0004674; GO:0009636,ATP binding; apical plasma membrane; brush border membrane; calcium channel activity; cation channel activity; integral to membrane; metal ion binding; metal ion transport; protein serine/threonine kinase activity; response to toxic substance,PF02816;PF00520;PF16519;,2.00E-15,CHOYP_BRAFLDRAFT_118277.1.1,,,,,,,TRPM6_MOUSE,Mus musculus (Mouse),metal ion transport [GO:0030001]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636] comp131297_c2_seq1,598,47.1572,0.60407591,49,27,,,,,,,,,5.00E-24,CHOYP_BRAFLDRAFT_118277.1.1,,,,,,,,, comp131298_c1_seq1,911,45.8836,0.25054402,27,44,,4.00E-119,Q5U5R9,Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2),Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2),GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,1.00E-116,CHOYP_HECTD2.1.1,,,,,,,HECD2_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp131299_c0_seq1,1512,40.0794,1.11110171,41,235,,2.00E-61,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,5.00E-16,CHOYP_LOC100374651.1.4,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp131300_c0_seq2,1649,34.2632,0.48550539,0,13,,1.00E-52,Q5XIU9,Membrane-associated progesterone receptor component 2,Membrane-associated progesterone receptor component 2,GO:0020037; GO:0016021; GO:0005496,heme binding; integral to membrane; steroid binding,PF00173;,,,,,,,,,PGRC2_RAT,Rattus norvegicus (Rat), comp131300_c0_seq3,1662,34.1757,0.48382177,0,0,,,,,,,,,5.00E-42,CHOYP_PGRMC1.1.1,,,,,,,,, comp131308_c0_seq2,1039,40.231,0.57065205,13,19,,,,,,,,,4.00E-85,CHOYP_PPP2R3B.2.2,,,,,,,,, comp131308_c0_seq3,344,42.1512,0.75658534,5,16,,2.00E-56,Q9Y5P8,Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit),Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit),GO:0000082; GO:0005509; GO:0007050; GO:0005654; GO:0006470; GO:0000159; GO:0008601; GO:0004722,G1/S transition of mitotic cell cycle; calcium ion binding; cell cycle arrest; nucleoplasm; protein dephosphorylation; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity,PF13499;,,,,,,,,,P2R3B_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; protein dephosphorylation [GO:0006470] comp131312_c0_seq1,1424,38.6236,0.35733708,349,3095,,6.00E-34,Q9NZM5,Glioma tumor suppressor candidate region gene 2 protein (p60),Glioma tumor suppressor candidate region gene 2 protein (p60),GO:0005730,nucleolus,PF07767;,4.00E-11,CHOYP_ISCW_ISCW008669.1.1,2.00E-89,ruditapes2_c1414,,,,,GSCR2_HUMAN,Homo sapiens (Human), comp131313_c0_seq1,1082,44.732,0.57849523,6,163,,6.00E-91,Q96T60,Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)],Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)],GO:0005524; GO:0046404; GO:0042769; GO:0006261; GO:0003684; GO:0003690; GO:0004519; GO:0005730; GO:0019201; GO:0000718; GO:0046403; GO:0006979; GO:0009314,"ATP binding; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; DNA damage response, detection of DNA damage; DNA-dependent DNA replication; damaged DNA binding; double-stranded DNA binding; endonuclease activity; nucleolus; nucleotide kinase activity; nucleotide-excision repair, DNA damage removal; polynucleotide 3'-phosphatase activity; response to oxidative stress; response to radiation",PF08645;,4.00E-47,CHOYP_LOC586494.1.1,,,,,,,PNKP_HUMAN,Homo sapiens (Human),"dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; nucleotide-excision repair, DNA damage removal [GO:0000718]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]" comp131314_c3_seq1,1858,37.1367,0.26703233,0,0,,1.00E-12,Q6NYG6,Tudor domain-containing protein 3,Tudor domain-containing protein 3,GO:0003723; GO:0003682; GO:0016568; GO:0005737; GO:0006397; GO:0035064; GO:0005634; GO:0003713,RNA binding; chromatin binding; chromatin modification; cytoplasm; mRNA processing; methylated histone residue binding; nucleus; transcription coactivator activity,PF08585;PF06003;PF00627;,,,,,,,,,TDRD3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chromatin modification [GO:0016568]; mRNA processing [GO:0006397] comp131314_c3_seq2,2099,37.1606,0.3233019,16,51,,1.00E-09,Q6P1U3,Tudor domain-containing protein 3,Tudor domain-containing protein 3,GO:0003682; GO:0016568; GO:0005737; GO:0035064; GO:0005634; GO:0003713,chromatin binding; chromatin modification; cytoplasm; methylated histone residue binding; nucleus; transcription coactivator activity,PF08585;PF00567;PF00627;,,,,,,,,,TDRD3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chromatin modification [GO:0016568] comp131323_c1_seq1,876,37.7854,0.48186876,4,0,,,,,,,,,1.00E-26,CHOYP_LOC100121198.1.1,,,,,,,,, comp131323_c1_seq3,974,39.7331,0.47101499,33,11,,1.00E-13,Q2KHR3,Glutamine and serine-rich protein 1,Glutamine and serine-rich protein 1,,,PF13926;,,,,,,,,,QSER1_HUMAN,Homo sapiens (Human), comp131329_c0_seq1,680,38.9706,0.64857283,81,41,,1.00E-68,Q642C0,DnaJ homolog subfamily C member 8,DnaJ homolog subfamily C member 8,,,PF00226;,3.00E-77,CHOYP_LOC100368924.1.1,,,,,,,DNJC8_RAT,Rattus norvegicus (Rat), comp131331_c0_seq1,1500,41.3333,0.45352649,69,331,,3.00E-156,Q6GLP4,Protein RMD5 homolog A,Protein RMD5 homolog A,,,PF10607;,3.00E-82,CHOYP_LOC100124228.1.1,,,,,,,RMD5A_XENLA,Xenopus laevis (African clawed frog), comp131331_c0_seq2,1075,41.2093,0.52680584,0,7,,1.00E-69,Q6GLP4,Protein RMD5 homolog A,Protein RMD5 homolog A,,,PF10607;,,,,,,,,,RMD5A_XENLA,Xenopus laevis (African clawed frog), comp131335_c0_seq1,2422,36.0446,0.6795664,4207,462,,9.00E-51,Q9H4K1,RIB43A-like with coiled-coils protein 2,RIB43A-like with coiled-coils protein 2,,,PF05914;,0,CHOYP_WDR11.2.2,9.00E-13,ruditapes_c27179,1.00E-128,AM857430.p.cg.6,5,,RIBC2_HUMAN,Homo sapiens (Human), comp131337_c0_seq1,1831,37.2474,0.36600228,0,0,,2.00E-55,O35790,N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L),N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L),GO:0006506; GO:0000225; GO:0042406; GO:0016021,GPI anchor biosynthetic process; N-acetylglucosaminylphosphatidylinositol deacetylase activity; extrinsic to endoplasmic reticulum membrane; integral to membrane,PF02585;,,,,,,,,,PIGL_RAT,Rattus norvegicus (Rat),GPI anchor biosynthetic process [GO:0006506] comp131337_c0_seq2,210,45.2381,0.2877338,2,0,,1.00E-18,P07032,"Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase isozyme CH2) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)","Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase isozyme CH2) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)",GO:0003998,acylphosphatase activity,PF00708;,,,,,,,,,ACYP1_CHICK,Gallus gallus (Chicken), comp131337_c0_seq3,1876,37.2068,0.35783507,0,0,,2.00E-55,O35790,N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L),N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L),GO:0006506; GO:0000225; GO:0042406; GO:0016021,GPI anchor biosynthetic process; N-acetylglucosaminylphosphatidylinositol deacetylase activity; extrinsic to endoplasmic reticulum membrane; integral to membrane,PF02585;,,,,,,,,,PIGL_RAT,Rattus norvegicus (Rat),GPI anchor biosynthetic process [GO:0006506] comp131337_c0_seq5,1848,37.3918,0.37571766,0,0,,4.00E-07,A1SPV1,Acylphosphatase (EC 3.6.1.7) (Acylphosphate phosphohydrolase),Acylphosphatase (EC 3.6.1.7) (Acylphosphate phosphohydrolase),GO:0003998,acylphosphatase activity,PF00708;,,,,,,,,,ACYP_NOCSJ,Nocardioides sp. (strain ATCC BAA-499 / JS614), comp131340_c0_seq1,1598,35.2315,0.38354052,0,6,,2.00E-32,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp131340_c0_seq2,2931,35.5851,0.36988339,108,268,,1.00E-33,Q9N003,Zinc finger protein 425 (Fragment),Zinc finger protein 425 (Fragment),GO:0003677; GO:0005737; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN425_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp131341_c0_seq4,1036,37.8378,0.30730093,0,0,,2.00E-25,Q6GLQ4,Serine/threonine-protein phosphatase 1 regulatory subunit 10,Serine/threonine-protein phosphatase 1 regulatory subunit 10,GO:0003677; GO:0046872; GO:0005634; GO:0004864; GO:0006351,"DNA binding; metal ion binding; nucleus; protein phosphatase inhibitor activity; transcription, DNA-dependent",PF08711;,,,,,,,,,PP1RA_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp131353_c0_seq1,1556,34.8329,0.55248958,872,3943,,1.00E-108,Q5R9Z1,Vacuolar protein sorting-associated protein 29 (EC 3.1.3.3) (Vesicle protein sorting 29),Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29),GO:0010008; GO:0046872; GO:0004647; GO:0015031,endosome membrane; metal ion binding; phosphoserine phosphatase activity; protein transport,PF12850;,1.00E-118,CHOYP_VPS29.1.1,,,,,,,VPS29_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp131354_c0_seq1,450,42.6667,0.24599227,1,0,,4.00E-06,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131367_c0_seq1,1231,40.9423,0.90357202,17,173,,2.00E-54,Q5I0M0,Histone-lysine N-methyltransferase SETMAR (EC 2.1.1.43) (SET domain and mariner transposase fusion gene-containing protein homolog),Histone-lysine N-methyltransferase SETMAR (EC 2.1.1.43) (SET domain and mariner transposase fusion protein homolog),GO:0005694; GO:0018024; GO:0005634; GO:0008270,chromosome; histone-lysine N-methyltransferase activity; nucleus; zinc ion binding,PF05033;PF00856;,,,,,,,,,SETMR_RAT,Rattus norvegicus (Rat),histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568] comp131371_c0_seq1,2277,43.9174,0.63363499,813,5307,,0,Q5ZM11,"Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)","Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)",GO:0005524; GO:0004814; GO:0006420; GO:0005737,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation; cytoplasm,PF03485;PF05746;PF00750;,0,CHOYP_SYRC.1.2,,,,,,,SYRC_CHICK,Gallus gallus (Chicken),arginyl-tRNA aminoacylation [GO:0006420] comp131374_c0_seq1,1387,37.0584,0.66846915,88,17,,6.00E-42,A8WG43,Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein),Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein),GO:0005737; GO:0005634,cytoplasm; nucleus,,2.00E-46,CHOYP_LOC100368248.1.1,,,,,,,CCD89_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp131374_c0_seq2,510,39.6078,1.11296339,3,0,,9.00E-06,Q2TAM9,Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9),Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9),,,,,,,,,,,,TUSC1_HUMAN,Homo sapiens (Human), comp131376_c0_seq1,584,43.1507,0.37900986,12,114,,2.00E-29,Q8BTK5,SET and MYND domain-containing protein 4 (EC 2.1.1.-),SET and MYND domain-containing protein 4 (EC 2.1.1.-),GO:0046872; GO:0008168,metal ion binding; methyltransferase activity,PF00856;PF01753;,,,,,,,,,SMYD4_MOUSE,Mus musculus (Mouse), comp131385_c0_seq3,453,41.5011,0.56750277,39,333,,9.00E-43,O95563,Mitochondrial pyruvate carrier 2 (Brain protein 44),Mitochondrial pyruvate carrier 2 (Brain protein 44),GO:0016021; GO:0005743; GO:0006850; GO:0005739; GO:0006090; GO:0050833,integral to membrane; mitochondrial inner membrane; mitochondrial pyruvate transport; mitochondrion; pyruvate metabolic process; pyruvate transmembrane transporter activity,PF03650;,6.00E-15,CHOYP_PHUM_PHUM335300.1.1,2.00E-57,ruditapes_c12385,,,,,MPC2_HUMAN,Homo sapiens (Human),mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; mitochondrial pyruvate transmembrane transport [GO:1902361]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] comp131387_c2_seq1,1446,44.3292,0.56706209,89,39,,4.00E-54,Q08180,Irregular chiasm C-roughest protein (Protein IRREC),Irregular chiasm C-roughest protein (Protein IRREC),GO:0045177; GO:0005913; GO:0046667; GO:0007156; GO:0016021; GO:0046331; GO:0007520; GO:0005886; GO:0016202,apical part of cell; cell-cell adherens junction; compound eye retinal cell programmed cell death; homophilic cell adhesion; integral to membrane; lateral inhibition; myoblast fusion; plasma membrane; regulation of striated muscle tissue development,PF08205;PF07679;PF13895;,,,,,,,,,ICCR_DROME,Drosophila melanogaster (Fruit fly),axonogenesis [GO:0007409]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lateral inhibition [GO:0046331]; myoblast fusion [GO:0007520]; regulation of striated muscle tissue development [GO:0016202]; retinal cell programmed cell death [GO:0046666] comp131388_c0_seq2,583,46.1407,0.87367278,59,92,,4.00E-11,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp131390_c0_seq1,1817,37.4794,0.44097939,14,13,,1.00E-18,Q8CAS9,Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog),Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog),GO:0003950; GO:0005737; GO:0005829; GO:0006302; GO:0005634; GO:0060330,NAD+ ADP-ribosyltransferase activity; cytoplasm; cytosol; double-strand break repair; nucleus; regulation of response to interferon-gamma,PF01661;,,,,,,,,,PARP9_MOUSE,Mus musculus (Mouse),double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330] comp131390_c0_seq3,1785,36.9748,0.46126048,3,9,,2.00E-23,Q9WYX8,Uncharacterized protein TM_0508,Uncharacterized protein TM_0508,GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009378,ATP binding; DNA binding; DNA recombination; DNA repair; DNA replication; four-way junction helicase activity,PF16193;PF01661;PF12002;PF05496;,,,,,,,,,Y508_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp131392_c0_seq1,1522,35.9396,0.39273904,7,50,,7.00E-96,Q7T3F7,Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (Morgana),Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (Morgana),GO:0046872; GO:0010824,metal ion binding; regulation of centrosome duplication,PF04968;PF04969;,,,,,,,,,CHRD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of centrosome duplication [GO:0010824] comp131392_c0_seq2,1451,35.7684,0.39469649,0,5,,6.00E-14,Q9SE33,Cysteine and histidine-rich domain-containing protein RAR1 (AtRAR1) (CHORD domain-containing protein RAR1) (Protein PPHB SUSCEPTIBLE 2) (Protein REQUIRED FOR MLA12 RESISTANCE 1),Cysteine and histidine-rich domain-containing protein RAR1 (AtRAR1) (CHORD domain-containing protein RAR1) (Protein PPHB SUSCEPTIBLE 2) (Protein REQUIRED FOR MLA12 RESISTANCE 1),GO:0009816; GO:0009817; GO:0009626; GO:0050821; GO:0002679; GO:0008270,"defense response to bacterium, incompatible interaction; defense response to fungus, incompatible interaction; plant-type hypersensitive response; protein stabilization; respiratory burst involved in defense response; zinc ion binding",PF04968;,1.00E-24,CHOYP_CHRD1.1.1,,,,,,,RAR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"defense response to bacterium [GO:0042742]; defense response to bacterium, incompatible interaction [GO:0009816]; defense response to fungus, incompatible interaction [GO:0009817]; plant-type hypersensitive response [GO:0009626]; protein stabilization [GO:0050821]; respiratory burst involved in defense response [GO:0002679]" comp131393_c0_seq2,916,40.7205,0.43120018,17,85,,3.00E-10,Q6PFX9,Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),GO:0005794; GO:0000139; GO:0003950; GO:0016055; GO:0051301; GO:0000775; GO:0051028; GO:0007067; GO:0043392; GO:0000784; GO:0005643; GO:0018105; GO:0018107; GO:0090263; GO:0032212; GO:0045944; GO:0070213; GO:0070198; GO:0070212; GO:0000209; GO:0015031; GO:0000922; GO:0008270,"Golgi apparatus; Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; cell division; chromosome, centromeric region; mRNA transport; mitosis; negative regulation of DNA binding; nuclear chromosome, telomeric region; nuclear pore; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of telomere maintenance via telomerase; positive regulation of transcription from RNA polymerase II promoter; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein poly-ADP-ribosylation; protein polyubiquitination; protein transport; spindle pole; zinc ion binding",PF00023;PF12796;PF13606;PF00644;PF07647;,,,,,,,,,TNKS1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]" comp131396_c0_seq1,943,45.3871,0.66486264,0,246,,4.00E-19,Q8VHX6,Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),GO:0030018; GO:0003779; GO:0015629; GO:0030029; GO:0048747; GO:0042383,Z disc; actin binding; actin cytoskeleton; actin filament-based process; muscle fiber development; sarcolemma,PF00307;PF00630;,,,,,,,,,FLNC_MOUSE,Mus musculus (Mouse),actin filament-based process [GO:0030029]; muscle fiber development [GO:0048747] comp131401_c0_seq1,820,42.1951,0.60551902,15,1,,1.00E-104,P0CW70,Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2),Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2),GO:0016021; GO:0007275; GO:0007286; GO:0016757,"integral to membrane; multicellular organismal development; spermatid development; transferase activity, transferring glycosyl groups",PF10034;,6.00E-94,CHOYP_BRAFLDRAFT_269194.1.1,,,,,,,D19L2_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]; spermatid development [GO:0007286] comp131401_c0_seq2,674,42.2849,0.70055507,0,0,,5.00E-40,Q6NXN4,Putative C-mannosyltransferase DPY19L2P1 (EC 2.4.1.-) (Dpy-19-like protein 2 pseudogene 1) (Protein dpy-19 homolog 2-like 1),Putative C-mannosyltransferase DPY19L2P1 (EC 2.4.1.-) (Dpy-19-like protein 2 pseudogene 1) (Protein dpy-19 homolog 2-like 1),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF10034;,,,,,,,,,D19P1_HUMAN,Homo sapiens (Human),spermatid development [GO:0007286] comp131401_c1_seq1,1621,39.235,0.37343731,112,10,,1.00E-118,Q2PZI1,Probable C-mannosyltransferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1),Probable C-mannosyltransferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF10034;,,,,,,,,,D19L1_HUMAN,Homo sapiens (Human),protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] comp131402_c0_seq1,1655,38.852,0.5484514,8,75,,3.00E-122,Q5SSI6,U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50),U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50),GO:0005730; GO:0006364,nucleolus; rRNA processing,,2.00E-84,CHOYP_LOC100378445.1.1,,,,,,,UTP18_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp131402_c0_seq2,1670,38.7425,0.5471304,3,89,,8.00E-08,Q8YTC2,Uncharacterized WD repeat-containing protein alr2800,Uncharacterized WD repeat-containing protein alr2800,GO:0043531; GO:0006952; GO:0006355,"ADP binding; defense response; regulation of transcription, DNA-dependent",PF00931;PF00400;,,,,,,,,,Y2800_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp131404_c0_seq2,2010,41.8408,0.5013884,76,32,,2.00E-46,Q921R4,DnaJ homolog subfamily C member 14,DnaJ homolog subfamily C member 14,GO:0005789; GO:0016021; GO:0015031,endoplasmic reticulum membrane; integral to membrane; protein transport,PF00226;PF14901;,3.00E-108,CHOYP_LOC100114549.1.1,,,,,,,DJC14_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp131404_c0_seq3,933,43.7299,0.44886634,0,0,,2.00E-16,Q9QYJ3,DnaJ homolog subfamily B member 1 (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40),DnaJ homolog subfamily B member 1 (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40),GO:0070389; GO:0051085; GO:0005737; GO:0005730; GO:0006950,chaperone cofactor-dependent protein refolding; chaperone mediated protein folding requiring cofactor; cytoplasm; nucleolus; response to stress,PF00226;PF01556;,9.00E-42,CHOYP_LOC100114549.1.1,,,,,,,DNJB1_MOUSE,Mus musculus (Mouse),chaperone cofactor-dependent protein refolding [GO:0070389]; chaperone mediated protein folding requiring cofactor [GO:0051085]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781] comp131405_c0_seq1,1422,44.5851,0.75642182,544,2595,,2.00E-122,Q7SZS2,Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein),Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein),GO:0009056; GO:0016788; GO:0008270,"catabolic process; hydrolase activity, acting on ester bonds; zinc ion binding",PF02126;,,,,,,,,,PTER_XENLA,Xenopus laevis (African clawed frog),catabolic process [GO:0009056] comp131407_c1_seq1,940,46.7021,0.7105768,17,92,,9.00E-15,P85120,Daple-like protein (Coiled-coil domain-containing protein 88C-like) (Dvl-associating protein with a high frequency of leucine residues-like) (xDal),Daple-like protein (Coiled-coil domain-containing protein 88C-like) (Dvl-associating protein with a high frequency of leucine residues-like) (xDal),GO:0030165; GO:0060071; GO:0007257; GO:0060070; GO:0009950; GO:0001736,"PDZ domain binding; Wnt receptor signaling pathway, planar cell polarity pathway; activation of JUN kinase activity; canonical Wnt receptor signaling pathway; dorsal/ventral axis specification; establishment of planar polarity",PF05622;,4.00E-15,CHOYP_GRDN.1.5,,,,,,,DAPLE_XENLA,Xenopus laevis (African clawed frog),"activation of JUN kinase activity [GO:0007257]; canonical Wnt signaling pathway [GO:0060070]; dorsal/ventral axis specification [GO:0009950]; establishment of planar polarity [GO:0001736]; stress-activated protein kinase signaling cascade [GO:0031098]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp131409_c0_seq2,1218,35.8785,0.69020304,31,201,,3.00E-09,Q99MB1,Toll-like receptor 3 (CD antigen CD283),Toll-like receptor 3 (CD antigen CD283),GO:0007252; GO:0002756; GO:0071260; GO:0051607; GO:0003725; GO:0005789; GO:0010008; GO:0006954; GO:0045087; GO:0016021; GO:0043123; GO:0046330; GO:0042346; GO:0051092; GO:0045080; GO:0032722; GO:0050729; GO:0045356; GO:0045359; GO:0032728; GO:0045078; GO:0032735; GO:0032755; GO:0032757; GO:0034123; GO:0045944; GO:0032760; GO:0034346; GO:0043330; GO:0034138; GO:0004888,I-kappaB phosphorylation; MyD88-independent toll-like receptor signaling pathway; cellular response to mechanical stimulus; defense response to virus; double-stranded RNA binding; endoplasmic reticulum membrane; endosome membrane; inflammatory response; innate immune response; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of NF-kappaB import into nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of chemokine biosynthetic process; positive regulation of chemokine production; positive regulation of inflammatory response; positive regulation of interferon-alpha biosynthetic process; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-beta production; positive regulation of interferon-gamma biosynthetic process; positive regulation of interleukin-12 production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of toll-like receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of type III interferon production; response to exogenous dsRNA; toll-like receptor 3 signaling pathway; transmembrane signaling receptor activity,PF00560;PF13855;PF01582;,,,,,,,,,TLR3_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to interferon-beta [GO:0035458]; cellular response to interferon-gamma [GO:0071346]; cellular response to mechanical stimulus [GO:0071260]; defense response [GO:0006952]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; microglial cell activation involved in immune response [GO:0002282]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; necroptotic signaling pathway [GO:0097527]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-alpha biosynthetic process [GO:0045356]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of toll-like receptor signaling pathway [GO:0034123]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type III interferon production [GO:0034346]; positive regulation of type I interferon production [GO:0032481]; regulation of dendritic cell cytokine production [GO:0002730]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor signaling pathway [GO:0002224] comp131415_c0_seq1,882,32.0862,0.26500634,2291,755,,1.00E-19,A6NNX1,RIIa domain-containing protein 1,RIIa domain-containing protein 1,,,PF02197;,8.00E-36,CHOYP_LOC100369985.1.1,2.00E-60,ruditapes_c27542,,,,,RIAD1_HUMAN,Homo sapiens (Human), comp131434_c0_seq3,1494,43.1727,0.5133125,42,116,,0,Q32LQ6,Major facilitator superfamily domain-containing protein 1,Major facilitator superfamily domain-containing protein 1,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,1.00E-149,CHOYP_BRAFLDRAFT_277055.1.2,,,,,,,MFSD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),transmembrane transport [GO:0055085] comp131440_c0_seq1,747,29.3173,0.62762321,14,145,,9.00E-10,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp131443_c0_seq1,1598,42.7409,0.46177492,89,260,,3.00E-87,Q9N1T2,X-linked retinitis pigmentosa GTPase regulator,X-linked retinitis pigmentosa GTPase regulator,GO:0005794; GO:0005813; GO:0042384; GO:0035085; GO:0036064; GO:0005085; GO:0042073; GO:0050896; GO:0036126; GO:0007601,Golgi apparatus; centrosome; cilium assembly; cilium axoneme; cilium basal body; guanyl-nucleotide exchange factor activity; intraflagellar transport; response to stimulus; sperm flagellum; visual perception,PF00415;,2.00E-47,CHOYP_RPGRB.1.1,,,,,,,RPGR_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp131445_c0_seq2,591,42.978,0.34055706,42,269,,2.00E-49,Q6DKE0,"Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)","Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)",GO:0047837; GO:0047115,"D-xylose 1-dehydrogenase (NADP+) activity; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity",PF01408;,,,,,,,,,DHDH_XENLA,Xenopus laevis (African clawed frog), comp131451_c2_seq1,489,41.9223,0.52503629,0,0,,5.00E-09,Q3U3C9,Genetic suppressor element 1,Genetic suppressor element 1,,,PF12540;,,,,,,,,,GSE1_MOUSE,Mus musculus (Mouse), comp131454_c0_seq1,988,43.0162,0.77525275,2,210,female>male,2.00E-50,Q8BM89,Arylsulfatase J (ASJ) (EC 3.1.6.-),Arylsulfatase J (ASJ) (EC 3.1.6.-),GO:0005576; GO:0046872; GO:0008484,extracellular region; metal ion binding; sulfuric ester hydrolase activity,PF00884;,1.00E-14,CHOYP_BRAFLDRAFT_206907.4.11,,,,,,,ARSJ_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp131457_c0_seq1,1687,41.5531,0.84950116,2316,18,male>female,6.00E-64,Q0VAA2,Uncharacterized protein C14orf166B,Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74),,,PF13516;,1.00E-17,CHOYP_LOC100372392.5.8,,,,,,,CN16B_HUMAN,Homo sapiens (Human), comp131458_c0_seq1,953,39.7692,0.34905752,18,146,,5.00E-73,Q96AB6,Protein N-terminal asparagine amidohydrolase (EC 3.5.1.-) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein N-terminal asparagine amidase) (Protein NTN-amidase),Protein N-terminal asparagine amidohydrolase (EC 3.5.1.-) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein N-terminal asparagine amidase) (Protein NTN-amidase),GO:0008344; GO:0005737; GO:0007613; GO:0005634; GO:0008418,adult locomotory behavior; cytoplasm; memory; nucleus; protein-N-terminal asparagine amidohydrolase activity,PF14736;,6.00E-13,CHOYP_RSSA.10.10,,,,,,,NTAN1_HUMAN,Homo sapiens (Human),adult locomotory behavior [GO:0008344]; memory [GO:0007613] comp131459_c0_seq1,1896,42.5633,0.52445183,0,0,,3.00E-43,B2RX12,Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3),Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3),GO:0005524; GO:0006200; GO:0042626; GO:0005887,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to plasma membrane",PF00664;PF00005;,,,,,,,,,MRP3_MOUSE,Mus musculus (Mouse),canalicular bile acid transport [GO:0015722] comp131459_c0_seq2,2002,43.7063,0.5549464,0,0,,1.00E-97,P82451,ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2),ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0006813; GO:0008281,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; potassium ion transport; sulfonylurea receptor activity",PF00664;PF00005;,,,,,,,,,ABCC9_RABIT,Oryctolagus cuniculus (Rabbit),potassium ion transport [GO:0006813] comp131459_c0_seq3,1537,43.9167,0.48754908,0,0,,6.00E-44,B2RX12,Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3),Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3),GO:0005524; GO:0006200; GO:0042626; GO:0005887,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to plasma membrane",PF00664;PF00005;,6.00E-28,CHOYP_BRAFLDRAFT_118957.1.1,,,,,,,MRP3_MOUSE,Mus musculus (Mouse),canalicular bile acid transport [GO:0015722] comp131459_c0_seq4,1643,45.2222,0.52605724,0,0,,1.00E-76,P82451,ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2),ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0006813; GO:0008281,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; potassium ion transport; sulfonylurea receptor activity",PF00664;PF00005;,,,,,,,,,ABCC9_RABIT,Oryctolagus cuniculus (Rabbit),potassium ion transport [GO:0006813] comp131467_c0_seq1,1292,40.6347,0.62266914,23,147,,2.00E-63,O00338,Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2),Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2),GO:0050427; GO:0009308; GO:0005829; GO:0015630; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine metabolic process; cytosol; microtubule cytoskeleton; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1C2_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; sulfation [GO:0051923] comp131473_c0_seq2,919,47.6605,0.52922064,0,0,,5.00E-141,Q8IVB5,LIX1-like protein,LIX1-like protein,,,PF14954;,5.00E-159,CHOYP_LIX1L.1.1,,,,,,,LIX1L_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352] comp131473_c0_seq3,1408,44.4602,0.59802308,29,6,,,,,,,,,8.00E-159,CHOYP_LIX1L.1.1,,,,,,,,, comp131477_c0_seq1,1671,42.1305,0.64055618,377,2581,,6.00E-53,Q6AXX4,Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (Disrupter of silencing SAS10) (UTP3 homolog),Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (Disrupter of silencing SAS10) (UTP3 homolog),GO:0007420; GO:0016568; GO:0005730; GO:0005634,brain development; chromatin modification; nucleolus; nucleus,PF09368;PF04000;,4.00E-37,CHOYP_ISCW_ISCW011328.1.1,,,,,,,SAS10_RAT,Rattus norvegicus (Rat),"brain development [GO:0007420]; chromatin modification [GO:0016568]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp131478_c1_seq1,1127,42.8571,0.38427915,73,33,,2.00E-94,Q96Q42,Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein),Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein),GO:0017137; GO:0017112; GO:0030676; GO:0016601; GO:0005087; GO:0030424; GO:0007409; GO:0001662; GO:0008219; GO:0005813; GO:0005829; GO:0030425; GO:0043197; GO:0005769; GO:0016197; GO:0007032; GO:0030426; GO:0001701; GO:0030027; GO:0007626; GO:0016020; GO:0007528; GO:0048812; GO:0043025; GO:0005543; GO:0032855; GO:0035022; GO:0014069; GO:0043234; GO:0008104; GO:0043539; GO:0001881; GO:0032313; GO:0051036; GO:0006979; GO:0001726; GO:0035249; GO:0031982; GO:0016050,"Rab GTPase binding; Rab guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; Ran guanyl-nucleotide exchange factor activity; axon; axonogenesis; behavioral fear response; cell death; centrosome; cytosol; dendrite; dendritic spine; early endosome; endosomal transport; endosome organization; growth cone; in utero embryonic development; lamellipodium; locomotory behavior; membrane; neuromuscular junction development; neuron projection morphogenesis; neuronal cell body; phospholipid binding; positive regulation of Rac GTPase activity; positive regulation of Rac protein signal transduction; postsynaptic density; protein complex; protein localization; protein serine/threonine kinase activator activity; receptor recycling; regulation of Rab GTPase activity; regulation of endosome size; response to oxidative stress; ruffle; synaptic transmission, glutamatergic; vesicle; vesicle organization",PF02493;PF00415;PF00621;PF02204;,8.00E-50,CHOYP_ALS2.1.3,,,,,,,ALS2_HUMAN,Homo sapiens (Human),"axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Rac protein signal transduction [GO:0035022]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050]" comp131478_c2_seq2,1560,44.5513,0.50460873,85,37,,9.00E-13,Q15034,Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3),Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3),GO:0005737; GO:0016023; GO:0005634; GO:0042787; GO:0004842,cytoplasm; cytoplasmic membrane-bounded vesicle; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC3_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp131484_c1_seq1,817,42.9621,0.75391818,0,4,,6.00E-08,P98094,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment),Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment),GO:0006958; GO:0004866; GO:0005615; GO:0006954; GO:0045087; GO:0010951,"complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; inflammatory response; innate immune response; negative regulation of endopeptidase activity",PF00207;PF07678;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_EPTBU,Eptatretus burgeri (Inshore hagfish),"complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]" comp131484_c1_seq3,1143,39.6325,0.8175977,0,0,,9.00E-26,Q8R422,CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109),CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_MOUSE,Mus musculus (Mouse),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp131492_c0_seq2,1597,40.3882,0.81591486,0,5,,7.00E-102,Q96GK7,Fumarylacetoacetate hydrolase domain-containing protein 2A (EC 3.-.-.-),Fumarylacetoacetate hydrolase domain-containing protein 2A (EC 3.-.-.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF01557;,,,,,,,,,FAH2A_HUMAN,Homo sapiens (Human),metabolic process [GO:0008152] comp131492_c0_seq3,1585,40.4416,0.81866223,0,0,,7.00E-114,Q6GLT8,Fumarylacetoacetate hydrolase domain-containing protein 2 (EC 3.-.-.-),Fumarylacetoacetate hydrolase domain-containing protein 2 (EC 3.-.-.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF01557;,2.00E-72,CHOYP_LOC763463.1.1,6.00E-127,ruditapes_c17348,,,,,FAHD2_XENLA,Xenopus laevis (African clawed frog),metabolic process [GO:0008152] comp131494_c0_seq6,668,42.515,0.30815362,0,0,,2.00E-20,Q8CH62,Oral cancer-overexpressed protein 1 homolog,Oral cancer-overexpressed protein 1 homolog,,,PF09811;,,,,,,,,,ORAV1_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; intra-S DNA damage checkpoint [GO:0031573]; meiotic DNA integrity checkpoint [GO:0044778]; mitotic DNA replication checkpoint [GO:0033314]; nucleotide-excision repair [GO:0006289] comp131496_c1_seq1,1006,51.3917,0.5029975,2,23,,,,,,,,,2.00E-11,CHOYP_LOC100371354.1.1,,,,,,,,, comp131497_c0_seq3,740,38.2432,0.90045734,0,65,,7.00E-18,A6QLU6,Probable G-protein coupled receptor 133,Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133),GO:0004930; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF01825;,,,,,,,,,GP133_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579] comp131500_c0_seq1,505,30.8911,0.50033156,9,66,,,,,,,,,3.00E-12,CHOYP_LOC584740.1.2,,,,,,,,, comp131515_c0_seq1,1057,41.8165,0.84567218,49,74,,2.00E-25,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp131516_c0_seq1,1734,46.0208,0.94257174,0,0,,2.00E-26,Q4VC17,A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS18_MOUSE,Mus musculus (Mouse),eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331] comp131516_c0_seq4,1712,46.0864,0.96374145,0,0,,3.00E-26,Q8TE60,A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS18_HUMAN,Homo sapiens (Human),eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331] comp131518_c2_seq1,2258,41.5412,0.55671193,119,382,,2.00E-37,Q60855,Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP),Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP),GO:0005524; GO:0070231; GO:0060555; GO:0060554; GO:0044257; GO:0071356; GO:0031264; GO:0097191; GO:0005739; GO:0019048; GO:0043124; GO:2001237; GO:2001243; GO:0036289; GO:0043123; GO:0046330; GO:0051092; GO:0043065; GO:2001238; GO:0032757; GO:0045651; GO:0001934; GO:0045944; GO:0051347; GO:0032760; GO:0051291; GO:0051260; GO:0004674; GO:0043235; GO:0070926; GO:2000377; GO:0097342; GO:1901026,ATP binding; T cell apoptotic process; activation of necroptosis by extracellular signals; activation of necroptosis of activated-T cells; cellular protein catabolic process; cellular response to tumor necrosis factor; death-inducing signaling complex; extrinsic apoptotic signaling pathway; mitochondrion; modulation by virus of host morphology or physiology; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of intrinsic apoptotic signaling pathway; peptidyl-serine autophosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-8 production; positive regulation of macrophage differentiation; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transferase activity; positive regulation of tumor necrosis factor production; protein heterooligomerization; protein homooligomerization; protein serine/threonine kinase activity; receptor complex; regulation of ATP:ADP antiporter activity; regulation of reactive oxygen species metabolic process; ripoptosome; ripoptosome assembly involved in necroptosis,PF00531;PF07714;PF12721;,,,,,,,,,RIPK1_MOUSE,Mus musculus (Mouse),amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to tumor necrosis factor [GO:0071356]; extrinsic apoptotic signaling pathway [GO:0097191]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; peptidyl-serine autophosphorylation [GO:0036289]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of necroptotic process [GO:0060545]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of ATP:ADP antiporter activity [GO:0070926]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to tumor necrosis factor [GO:0034612]; ripoptosome assembly [GO:0097343]; ripoptosome assembly involved in necroptotic process [GO:1901026]; T cell apoptotic process [GO:0070231]; viral process [GO:0016032] comp131520_c0_seq1,1106,40.3255,0.57598698,24,149,,5.00E-73,Q5R9U9,RWD domain-containing protein 2B,RWD domain-containing protein 2B,,,PF06544;PF05773;,2.00E-45,CHOYP_LOC100367663.1.1,,,,,,,RWD2B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp131522_c0_seq1,1526,39.6461,0.38495534,920,2440,,7.00E-47,Q5ZI69,"39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37)","39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF07147;,,,,,,,,,RM37_CHICK,Gallus gallus (Chicken),translation [GO:0006412] comp131526_c0_seq1,1828,39.6061,0.71742061,114,43,,4.00E-22,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp131536_c0_seq2,2647,43.5587,0.46144258,72,65,,0,Q9DBV3,Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34),Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_LOC586878.1.1,,,,,,,DHX34_MOUSE,Mus musculus (Mouse),"negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]" comp131540_c0_seq2,931,42.3201,0.56138762,54,168,,4.00E-127,P42337,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)",GO:0016303; GO:0035005; GO:0005943; GO:0005524; GO:0001525; GO:0006006; GO:0044029; GO:0030027; GO:2000811; GO:2000270; GO:0043524; GO:0005942; GO:0046934; GO:0048015; GO:0005886; GO:0033138; GO:0043491; GO:0030295; GO:0006468; GO:0004674; GO:2000653; GO:0040014,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ATP binding; angiogenesis; glucose metabolic process; hypomethylation of CpG island; lamellipodium; negative regulation of anoikis; negative regulation of fibroblast apoptotic process; negative regulation of neuron apoptotic process; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein kinase B signaling cascade; protein kinase activator activity; protein phosphorylation; protein serine/threonine kinase activity; regulation of genetic imprinting; regulation of multicellular organism growth",PF00454;PF00792;PF02192;PF00794;PF00613;,2.00E-81,CHOYP_PK3CA.1.1,,,,,,,PK3CA_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014] comp131542_c0_seq1,884,32.4661,0.47580706,24,333,,1.00E-52,Q8K4M5,COMM domain-containing protein 1 (Protein Murr1),COMM domain-containing protein 1 (Protein Murr1),GO:0031462; GO:0030054; GO:0006878; GO:0005507; GO:0005737; GO:0032088; GO:0005730; GO:0005634; GO:0031398; GO:0032434,Cul2-RING ubiquitin ligase complex; cell junction; cellular copper ion homeostasis; copper ion binding; cytoplasm; negative regulation of NF-kappaB transcription factor activity; nucleolus; nucleus; positive regulation of protein ubiquitination; regulation of proteasomal ubiquitin-dependent protein catabolic process,PF07258;,8.00E-36,CHOYP_LOC100890106.1.1,5.00E-93,ruditapes_c9838,,,,,COMD1_MOUSE,Mus musculus (Mouse),"cellular copper ion homeostasis [GO:0006878]; copper ion homeostasis [GO:0055070]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902072]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of sodium ion transmembrane transport [GO:1902306]; plasma membrane to endosome transport [GO:0048227]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein transport [GO:0015031]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; transcription, DNA-templated [GO:0006351]" comp131559_c0_seq2,1114,39.9461,0.27692712,7,41,,2.00E-103,Q96G03,Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphopentomutase) (EC 5.4.2.7),Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphopentomutase) (EC 5.4.2.7),GO:0005829; GO:0046386; GO:0019388; GO:0006006; GO:0005978; GO:0005980; GO:0000287; GO:0004614; GO:0008973; GO:0044281,cytosol; deoxyribose phosphate catabolic process; galactose catabolic process; glucose metabolic process; glycogen biosynthetic process; glycogen catabolic process; magnesium ion binding; phosphoglucomutase activity; phosphopentomutase activity; small molecule metabolic process,PF02878;PF02879;PF02880;PF00408;,,,,,,,,,PGM2_HUMAN,Homo sapiens (Human),deoxyribose phosphate catabolic process [GO:0046386]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; pentose-phosphate shunt [GO:0006098] comp131559_c0_seq3,935,40.3209,0.29654412,0,0,,,,,,,,,4.00E-46,CHOYP_PGM2.1.1,,,,,,,,, comp131564_c0_seq2,519,39.8844,0.59417474,12,351,,2.00E-10,Q54GP8,Glutaredoxin,Glutaredoxin,GO:0050661; GO:0045454; GO:0031154; GO:0005737; GO:0009055; GO:0043295; GO:0004364; GO:0005622; GO:0015035; GO:0006979,NADP binding; cell redox homeostasis; culmination involved in sorocarp development; cytoplasm; electron carrier activity; glutathione binding; glutathione transferase activity; intracellular; protein disulfide oxidoreductase activity; response to oxidative stress,PF00462;,,,,,,,,,GLRX_DICDI,Dictyostelium discoideum (Slime mold),cell redox homeostasis [GO:0045454]; culmination involved in sorocarp development [GO:0031154]; response to oxidative stress [GO:0006979] comp131564_c0_seq4,579,39.8964,0.80098444,114,60,,8.00E-12,Q0DAE4,Glutaredoxin-C8 (Glutaredoxin-C4 homolog),Glutaredoxin-C8 (Glutaredoxin-C4 homolog),GO:0045454; GO:0005737; GO:0009055; GO:0015035,cell redox homeostasis; cytoplasm; electron carrier activity; protein disulfide oxidoreductase activity,PF00462;,,,,,,,,,GRXC8_ORYSJ,Oryza sativa subsp. japonica (Rice),cell redox homeostasis [GO:0045454] comp131565_c1_seq3,959,44.7341,0.31645604,50,50,,3.00E-62,Q8I8U7,Transcription-associated protein 1 (dTRA1),Transcription-associated protein 1 (dTRA1),GO:0035267; GO:0000124; GO:0005737; GO:0016573; GO:0043486; GO:0005875; GO:0006909; GO:0016773; GO:0005703; GO:0045747; GO:0006355; GO:0006351; GO:0035222,"NuA4 histone acetyltransferase complex; SAGA complex; cytoplasm; histone acetylation; histone exchange; microtubule associated complex; phagocytosis; phosphotransferase activity, alcohol group as acceptor; polytene chromosome puff; positive regulation of Notch signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; wing disc pattern formation",PF02259;PF02260;PF00454;,1.00E-167,CHOYP_LOC100123553.1.1,,,,,,,TRA1_DROME,Drosophila melanogaster (Fruit fly),"DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H3 acetylation [GO:0043966]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]" comp131565_c1_seq5,894,48.8814,0.48876348,2,0,,4.00E-33,Q54T85,Probable transcription-associated protein 1,Probable transcription-associated protein 1,GO:0005524; GO:0035267; GO:0000125; GO:0004402; GO:0004672; GO:0003712,ATP binding; NuA4 histone acetyltransferase complex; PCAF complex; histone acetyltransferase activity; protein kinase activity; transcription cofactor activity,PF02259;,,,,,,,,,TRA1_DICDI,Dictyostelium discoideum (Slime mold),DNA repair [GO:0006281]; histone acetylation [GO:0016573]; protein phosphorylation [GO:0006468] comp131565_c1_seq7,1147,48.3871,0.44800617,32,32,,2.00E-142,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,,,,,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131567_c0_seq1,205,37.561,0.27800931,3,27,,5.00E-23,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp131569_c0_seq1,1503,39.9202,0.55208033,7,26,,4.00E-26,Q54EN4,Protein disulfide-isomerase 2 (PDI2) (EC 5.3.4.1),Protein disulfide-isomerase 2 (PDI2) (EC 5.3.4.1),GO:0045454; GO:0005788; GO:0006662; GO:0045335; GO:0003756; GO:0015035; GO:0009617; GO:0019953,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; phagocytic vesicle; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; response to bacterium; sexual reproduction,PF00085;,,,,,,,,,PDI2_DICDI,Dictyostelium discoideum (Slime mold),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to bacterium [GO:0009617]; response to endoplasmic reticulum stress [GO:0034976]; sexual reproduction [GO:0019953] comp131569_c0_seq2,1524,39.7638,0.54874682,0,68,,3.00E-140,Q9D1Q6,Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4),Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4),GO:0045454; GO:0009986; GO:0005788; GO:0005789; GO:0005793; GO:0009100; GO:0003756; GO:0034976; GO:0006986,cell redox homeostasis; cell surface; endoplasmic reticulum lumen; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; glycoprotein metabolic process; protein disulfide isomerase activity; response to endoplasmic reticulum stress; response to unfolded protein,PF00085;,,,,,,,,,ERP44_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] comp131569_c0_seq3,1405,40.3559,0.52756681,6,38,,1.00E-26,Q54EN4,Protein disulfide-isomerase 2 (PDI2) (EC 5.3.4.1),Protein disulfide-isomerase 2 (PDI2) (EC 5.3.4.1),GO:0045454; GO:0005788; GO:0006662; GO:0045335; GO:0003756; GO:0015035; GO:0009617; GO:0019953,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; phagocytic vesicle; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; response to bacterium; sexual reproduction,PF00085;,,,,,,,,,PDI2_DICDI,Dictyostelium discoideum (Slime mold),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to bacterium [GO:0009617]; response to endoplasmic reticulum stress [GO:0034976]; sexual reproduction [GO:0019953] comp131569_c0_seq4,1383,40.4917,0.53230797,27,90,,3.00E-149,Q9D1Q6,Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4),Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4),GO:0045454; GO:0009986; GO:0005788; GO:0005789; GO:0005793; GO:0009100; GO:0003756; GO:0034976; GO:0006986,cell redox homeostasis; cell surface; endoplasmic reticulum lumen; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; glycoprotein metabolic process; protein disulfide isomerase activity; response to endoplasmic reticulum stress; response to unfolded protein,PF00085;,6.00E-59,CHOYP_ERP44.1.1,,,,,,,ERP44_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] comp131570_c2_seq1,600,48,1.0161864,57,370,,7.00E-130,P09645,Tubulin alpha-8 chain (Fragment),Tubulin alpha-8 chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,8.00E-104,CHOYP_TBA1.7.9,7.00E-121,ruditapes2_c97,,,,,TBA8_CHICK,Gallus gallus (Chicken),microtubule-based process [GO:0007017] comp131570_c3_seq1,241,51.8672,0.93078526,20,66,,2.00E-38,P33628,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0005200,GTP binding; cytoplasm; microtubule; microtubule-based process; structural constituent of cytoskeleton,PF00091;,3.00E-41,CHOYP_LOC100373045.1.1,5.00E-36,ruditapes_c25365,,,,,TBA_PICAB,Picea abies (Norway spruce) (Picea excelsa),microtubule-based process [GO:0007017] comp131570_c4_seq1,551,38.657,1.38173171,99,304,,,,,,,,,4.00E-24,CHOYP_TUBA4A.1.1,3.00E-23,ruditapes_c4628,,,,,,, comp131571_c0_seq1,1578,38.6565,0.58670683,81,228,,6.00E-97,Q6GR25,Protein phosphatase PTC7 homolog (EC 3.1.3.16),Protein phosphatase PTC7 homolog (EC 3.1.3.16),GO:0008152; GO:0046872; GO:0004721,metabolic process; metal ion binding; phosphoprotein phosphatase activity,PF07228;,9.00E-70,CHOYP_PPTC7.1.1,,,,,,,PPTC7_XENLA,Xenopus laevis (African clawed frog), comp131575_c0_seq1,1397,41.947,0.4397253,18,0,,2.00E-108,Q9GKT2,Fatty acid hydroxylase domain-containing protein 2,Fatty acid hydroxylase domain-containing protein 2,GO:0006633; GO:0016021; GO:0005506; GO:0016491,fatty acid biosynthetic process; integral to membrane; iron ion binding; oxidoreductase activity,PF04116;,,,,,,,,,CE004_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),fatty acid biosynthetic process [GO:0006633] comp131575_c0_seq2,1051,42.3406,0.50999925,2,0,,1.00E-22,Q8L7W5,Methylsterol monooxygenase 1-1 (EC 1.14.13.72) (Sterol 4-alpha-methyl-oxidase 1-1) (AtSMO1-1),Methylsterol monooxygenase 1-1 (EC 1.14.13.72) (Sterol 4-alpha-methyl-oxidase 1-1) (AtSMO1-1),GO:0080064; GO:0005789; GO:0006633; GO:0016021; GO:0005506; GO:0016020; GO:0016126,"4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity; endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; iron ion binding; membrane; sterol biosynthetic process",PF04116;,2.00E-37,CHOYP_LOC100373768.1.1,,,,,,,SMO11_ARATH,Arabidopsis thaliana (Mouse-ear cress),"4,4-dimethyl-9beta,19-cyclopropylsterol oxidation [GO:0080064]; fatty acid biosynthetic process [GO:0006633]; sterol biosynthetic process [GO:0016126]" comp131580_c0_seq1,1546,39.9094,0.40636969,5,0,,7.00E-64,Q9UPW0,Forkhead box protein J3,Forkhead box protein J3,GO:0008301; GO:0009790; GO:0005634; GO:0007389; GO:0045893; GO:0043565; GO:0003700; GO:0009888; GO:0006351,"DNA binding, bending; embryo development; nucleus; pattern specification process; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tissue development; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXJ3_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp131580_c0_seq2,1600,40.0625,0.38965922,5,0,,7.00E-17,Q6EUW1,Forkhead box protein O3 (FoxO3) (xFoxO3),Forkhead box protein O3 (FoxO3) (xFoxO3),GO:0006915; GO:0005737; GO:0005829; GO:0005634; GO:0043525; GO:0045944; GO:0019901; GO:0043565; GO:0003700; GO:0006351,"apoptotic process; cytoplasm; cytosol; nucleus; positive regulation of neuron apoptotic process; positive regulation of transcription from RNA polymerase II promoter; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;PF16676;PF16675;,,,,,,,,,FOXO3_XENLA,Xenopus laevis (African clawed frog),"apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp131580_c0_seq3,1567,40.268,0.39381961,16,7,,9.00E-64,Q9UPW0,Forkhead box protein J3,Forkhead box protein J3,GO:0008301; GO:0009790; GO:0005634; GO:0007389; GO:0045893; GO:0043565; GO:0003700; GO:0009888; GO:0006351,"DNA binding, bending; embryo development; nucleus; pattern specification process; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tissue development; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXJ3_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp131580_c0_seq4,1513,40.119,0.41091298,3,0,,1.00E-31,Q708W2,Forkhead box protein J1-A (FoxJ1-A) (FoxJ1a) (xFoxJ1) (Forkhead protein 5) (xFKH5),Forkhead box protein J1-A (FoxJ1-A) (FoxJ1a) (xFoxJ1) (Forkhead protein 5) (xFKH5),GO:0003677; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"DNA binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,5.00E-73,CHOYP_FOXJ2_3.1.1,,,,,,,FXJ1A_XENLA,Xenopus laevis (African clawed frog),"cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131586_c0_seq1,1228,42.9153,0.86719841,41,686,,2.00E-56,P77735,Uncharacterized oxidoreductase YajO (EC 1.-.-.-),Uncharacterized oxidoreductase YajO (EC 1.-.-.-),GO:0016491; GO:0006772,oxidoreductase activity; thiamine metabolic process,PF00248;,,,,,,,,,YAJO_ECOLI,Escherichia coli (strain K12),thiamine metabolic process [GO:0006772] comp131591_c0_seq1,927,47.7886,0.92430386,0,242,,2.00E-59,A8DEZ8,Proline racemase (EC 5.1.1.4) (CdPRAC),Proline racemase (EC 5.1.1.4) (CdPRAC),GO:0018112,proline racemase activity,PF05544;,4.00E-15,CHOYP_T3HPD.2.2,,,,,,,PRAC_CLODI,Peptoclostridium difficile (Clostridium difficile), comp131591_c0_seq3,1068,47.7528,0.95506353,54,679,,6.00E-126,P0DKB4,Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-l-proline dehydratase),Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase),GO:0016836; GO:0050346,hydro-lyase activity; trans-L-3-hydroxyproline dehydratase activity,PF05544;,2.00E-19,CHOYP_T3HPD.1.2,,,,,,,T3HPD_SACKO,Saccoglossus kowalevskii (Acorn worm),metabolic process [GO:0008152] comp131592_c0_seq1,624,43.9103,0.17050458,55,7,,4.00E-08,P14730,WAP four-disulfide core domain protein 18 (Extracellular peptidase inhibitor) (Protein WDNM1) (Fragment),WAP four-disulfide core domain protein 18 (Extracellular peptidase inhibitor) (Protein WDNM1) (Fragment),GO:0005576; GO:0030414,extracellular region; peptidase inhibitor activity,PF00095;,,,,,,,,,EXPI_RAT,Rattus norvegicus (Rat), comp131592_c2_seq1,1353,44.272,0.21205014,88,0,,3.00E-13,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp131598_c0_seq1,1917,33.1247,0.53497514,1420,3965,,2.00E-09,Q4R3C7,Mitochondrial import receptor subunit TOM22 homolog (Translocase of outer membrane 22 kDa subunit homolog),Mitochondrial import receptor subunit TOM22 homolog (Translocase of outer membrane 22 kDa subunit homolog),GO:0016021; GO:0006886; GO:0005741,integral to membrane; intracellular protein transport; mitochondrial outer membrane,PF04281;,,,,,,,,,TOM22_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),intracellular protein transport [GO:0006886] comp131600_c0_seq1,993,41.6918,0.51111423,37,2,,9.00E-19,Q3T0S0,Transmembrane protein 128,Transmembrane protein 128,GO:0016021,integral to membrane,,,,,,,,,,TM128_BOVIN,Bos taurus (Bovine), comp131600_c0_seq2,711,42.616,0.56107282,0,0,,4.00E-19,Q3T0S0,Transmembrane protein 128,Transmembrane protein 128,GO:0016021,integral to membrane,,5.00E-31,CHOYP_BRAFLDRAFT_78425.1.1,,,,,,,TM128_BOVIN,Bos taurus (Bovine), comp131603_c0_seq1,1434,36.1227,0.49367321,1594,5773,,2.00E-56,Q29IK4,"39S ribosomal protein L22, mitochondrial (L22mt) (MRP-L22)","39S ribosomal protein L22, mitochondrial (L22mt) (MRP-L22)",GO:0015934; GO:0005739; GO:0003735; GO:0006412,large ribosomal subunit; mitochondrion; structural constituent of ribosome; translation,PF00237;,,,,,,,,,RM22_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),translation [GO:0006412] comp131604_c0_seq1,796,34.9246,0.54345745,574,1554,,5.00E-26,Q9CY16,"28S ribosomal protein S28, mitochondrial (MRP-S28) (S28mt)","28S ribosomal protein S28, mitochondrial (MRP-S28) (S28mt)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF10246;,,,,,,,,,RT28_MOUSE,Mus musculus (Mouse), comp131607_c0_seq2,1216,43.4211,0.82111741,0,0,,3.00E-10,B8DBZ5,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_LISMH,Listeria monocytogenes serotype 4a (strain HCC23),menaquinone biosynthetic process [GO:0009234] comp131607_c0_seq3,1782,42.6487,0.9078161,20,124,,5.00E-10,B8DBZ5,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_LISMH,Listeria monocytogenes serotype 4a (strain HCC23),menaquinone biosynthetic process [GO:0009234] comp131608_c0_seq1,2262,41.2025,0.47951108,3,0,,3.00E-77,Q6AYC5,Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15),Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15),GO:0030675; GO:0005737; GO:0016020; GO:0005543; GO:0008360; GO:0007165,Rac GTPase activator activity; cytoplasm; membrane; phospholipid binding; regulation of cell shape; signal transduction,PF00169;PF00620;,4.00E-25,CHOYP_RHG12.1.2,,,,,,,RHG15_RAT,Rattus norvegicus (Rat),regulation of cell shape [GO:0008360]; signal transduction [GO:0007165] comp131608_c0_seq2,1995,40.5514,0.41516185,8,0,,2.00E-72,A4IF90,Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15),Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15),GO:0030675; GO:0005737; GO:0016020; GO:0005543; GO:0008360; GO:0007165,Rac GTPase activator activity; cytoplasm; membrane; phospholipid binding; regulation of cell shape; signal transduction,PF00169;PF00620;,7.00E-22,CHOYP_RHG27.1.1,2.00E-76,ruditapes_c10494,,,,,RHG15_BOVIN,Bos taurus (Bovine),regulation of cell shape [GO:0008360]; signal transduction [GO:0007165] comp131608_c0_seq4,2340,41.453,0.47777753,7,19,,,,,,,,,5.00E-25,CHOYP_RHG12.1.2,,,,,,,,, comp131611_c0_seq1,1108,41.787,0.67627327,0,0,,2.00E-30,Q90972,E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (C-RZF) (RING finger protein 13),E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (C-RZF) (RING finger protein 13),GO:0016021; GO:0031902; GO:0005765; GO:0005634; GO:0051865; GO:0004842; GO:0008270,integral to membrane; late endosome membrane; lysosomal membrane; nucleus; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF02225;PF13639;,,,,,,,,,RNF13_CHICK,Gallus gallus (Chicken),protein autoubiquitination [GO:0051865] comp131611_c0_seq3,1080,41.9444,0.70955099,0,0,,3.00E-25,Q5XIL0,E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167),E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167),GO:0005737; GO:0012505; GO:0016021; GO:0045786; GO:0000209; GO:0004842; GO:0008270,cytoplasm; endomembrane system; integral to membrane; negative regulation of cell cycle; protein polyubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF02225;PF13639;,,,,,,,,,RN167_RAT,Rattus norvegicus (Rat),negative regulation of cell cycle [GO:0045786]; protein polyubiquitination [GO:0000209] comp131612_c0_seq1,765,37.9085,0.54910488,109,84,,5.00E-34,Q7Z449,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0008219; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0097267; GO:0006805,aromatase activity; cell death; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; omega-hydroxylase P450 pathway; xenobiotic metabolic process,PF00067;,,,,,,,,,CP2U1_HUMAN,Homo sapiens (Human),omega-hydroxylase P450 pathway [GO:0097267] comp131617_c1_seq1,1991,37.0166,1.01033814,72,258,,1.00E-37,Q0IIF9,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_BOVIN,Bos taurus (Bovine), comp131620_c0_seq2,846,38.7707,0.56262793,226,278,,1.00E-20,Q3SZM6,COX assembly mitochondrial protein homolog (Cmc1p),COX assembly mitochondrial protein homolog (Cmc1p),GO:0046872; GO:0005739,metal ion binding; mitochondrion,PF08583;,,,,,,,,,COXM1_BOVIN,Bos taurus (Bovine), comp131623_c0_seq2,508,33.8583,0.42588368,0,9,,,,,,,,,3.00E-19,CHOYP_LOC584740.1.2,,,,,,,,, comp131625_c1_seq12,1296,39.5062,0.28365244,0,0,,2.00E-07,P13864,DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT),DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT),GO:0003886; GO:0003723; GO:0071230; GO:0005721; GO:0016568; GO:0005737; GO:0016458; GO:0010216; GO:0008327; GO:0000122; GO:0005634; GO:0042127; GO:0005657; GO:0006351; GO:0008270,"DNA (cytosine-5-)-methyltransferase activity; RNA binding; cellular response to amino acid stimulus; centromeric heterochromatin; chromatin modification; cytoplasm; gene silencing; maintenance of DNA methylation; methyl-CpG binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of cell proliferation; replication fork; transcription, DNA-dependent; zinc ion binding",PF01426;PF06464;PF00145;PF12047;PF02008;,,,,,,,,,DNMT1_MOUSE,Mus musculus (Mouse),"aging [GO:0007568]; brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; cellular response to lead ion [GO:0071284]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin modification [GO:0016568]; chromatin silencing at rDNA [GO:0000183]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to activity [GO:0014823]; response to antidepressant [GO:0036276]; response to caffeine [GO:0031000]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; S-adenosylmethionine metabolic process [GO:0046500]; transcription, DNA-templated [GO:0006351]" comp131625_c1_seq4,778,42.2879,0.26769804,0,0,,1.00E-07,P13864,DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT),DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT),GO:0003886; GO:0003723; GO:0071230; GO:0005721; GO:0016568; GO:0005737; GO:0016458; GO:0010216; GO:0008327; GO:0000122; GO:0005634; GO:0042127; GO:0005657; GO:0006351; GO:0008270,"DNA (cytosine-5-)-methyltransferase activity; RNA binding; cellular response to amino acid stimulus; centromeric heterochromatin; chromatin modification; cytoplasm; gene silencing; maintenance of DNA methylation; methyl-CpG binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of cell proliferation; replication fork; transcription, DNA-dependent; zinc ion binding",PF01426;PF06464;PF00145;PF12047;PF02008;,,,,,,,,,DNMT1_MOUSE,Mus musculus (Mouse),"aging [GO:0007568]; brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; cellular response to lead ion [GO:0071284]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin modification [GO:0016568]; chromatin silencing at rDNA [GO:0000183]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to activity [GO:0014823]; response to antidepressant [GO:0036276]; response to caffeine [GO:0031000]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; S-adenosylmethionine metabolic process [GO:0046500]; transcription, DNA-templated [GO:0006351]" comp131632_c0_seq1,874,45.7666,0.5256446,52,111,,1.00E-12,Q7T2B9,Myotrophin,Myotrophin,GO:0005634; GO:0048471,nucleus; perinuclear region of cytoplasm,PF12796;,7.00E-56,CHOYP_LOC100371435.1.1,,,,,,,MTPN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp131633_c1_seq3,258,37.5969,0.33064327,0,25,,3.00E-09,Q17QR8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_BOVIN,Bos taurus (Bovine), comp131635_c1_seq1,1517,42.2544,0.9344993,0,0,,3.00E-10,P15989,Collagen alpha-3(VI) chain,Collagen alpha-3(VI) chain,GO:0007155; GO:0005581; GO:0004867,cell adhesion; collagen; serine-type endopeptidase inhibitor activity,PF01391;PF00014;PF00092;,,,,,,,,,CO6A3_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155] comp131635_c1_seq2,2075,42.8434,0.88777724,42,143,,3.00E-26,Q3SYW2,Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment],Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment],GO:0006958; GO:0005576; GO:0045087; GO:0006508; GO:0004252,"complement activation, classical pathway; extracellular region; innate immune response; proteolysis; serine-type endopeptidase activity",PF00084;PF00089;PF00092;,,,,,,,,,CO2_BOVIN,Bos taurus (Bovine),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]" comp131640_c0_seq1,428,48.5981,0.47813022,0,0,,1.00E-12,Q6PDN3,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687; GO:0014820,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity; tonic smooth muscle contraction,PF00041;PF07679;PF00069;,7.00E-14,CHOYP_LOC100367089.1.4,,,,,,,MYLK_MOUSE,Mus musculus (Mouse),aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to potassium ion [GO:0035865]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792] comp131640_c0_seq2,786,47.8372,0.69123217,14,17,,3.00E-10,Q97Z97,Kelch domain-containing protein SSO1033,Kelch domain-containing protein SSO1033,,,PF00041;PF01344;,1.00E-13,CHOYP_LOC100367089.4.4,,,,,,,Y1033_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2),protein ubiquitination [GO:0016567] comp131640_c1_seq2,461,49.8915,0.3152642,4,0,,4.00E-10,P97924,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0007409; GO:0005856; GO:0005085; GO:0035556; GO:0046872; GO:0043005; GO:0043025; GO:0048471; GO:0005543; GO:0004674; GO:0035023; GO:0050773,ATP binding; Rho guanyl-nucleotide exchange factor activity; axonogenesis; cytoskeleton; guanyl-nucleotide exchange factor activity; intracellular signal transduction; metal ion binding; neuron projection; neuronal cell body; perinuclear region of cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of dendrite development,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,,,,,,,,,KALRN_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023] comp131640_c1_seq3,2455,48.9613,0.59836112,0,0,,5.00E-71,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,6.00E-24,CHOYP_PHUM_PHUM226120.5.7,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp131640_c1_seq5,2505,48.9022,0.60119,6,5,,4.00E-25,Q14324,"Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)","Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)",GO:0007155; GO:0005829; GO:0030049; GO:0032982; GO:0008307,cell adhesion; cytosol; muscle filament sliding; myosin filament; structural constituent of muscle,PF00041;PF07679;,6.00E-24,CHOYP_TITIN.19.19,,,,,,,MYPC2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049] comp131640_c1_seq6,1136,49.4718,0.56193018,0,0,,2.00E-28,P52179,Myomesin-1 (190 kDa connectin-associated protein) (190 kDa titin-associated protein) (Myomesin family member 1),Myomesin-1 (190 kDa connectin-associated protein) (190 kDa titin-associated protein) (Myomesin family member 1),GO:0031430; GO:0006936; GO:0042803; GO:0005863; GO:0008307,M band; muscle contraction; protein homodimerization activity; striated muscle myosin thick filament; structural constituent of muscle,PF00041;PF07679;,3.00E-24,CHOYP_PHUM_PHUM226120.5.7,,,,,,,MYOM1_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp131640_c1_seq7,1709,49.3856,0.5665815,6,11,,7.00E-75,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,4.00E-24,CHOYP_TITIN.19.19,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp131641_c0_seq1,1875,45.0133,0.46908542,4,0,,0,Q96HU1,Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP),Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP),GO:0005097; GO:0017137; GO:0032486; GO:0007050; GO:0005737; GO:0005921; GO:0032851; GO:0045732,Rab GTPase activator activity; Rab GTPase binding; Rap protein signal transduction; cell cycle arrest; cytoplasm; gap junction; positive regulation of Rab GTPase activity; positive regulation of protein catabolic process,PF00566;PF02759;PF00018;,0,CHOYP_LOC100116018.1.1,,,,,,,SGSM3_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; cell cycle arrest [GO:0007050]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; Rap protein signal transduction [GO:0032486]; regulation of Rab protein signal transduction [GO:0032483]; regulation of vesicle fusion [GO:0031338] comp131641_c0_seq2,2017,43.2821,0.40614384,16,28,,3.00E-22,Q5SVR0,TBC1 domain family member 9B,TBC1 domain family member 9B,GO:0005097; GO:0005509; GO:0016021; GO:0032851,Rab GTPase activator activity; calcium ion binding; integral to membrane; positive regulation of Rab GTPase activity,PF02893;PF00566;,9.00E-78,CHOYP_SGSM3.2.3,,,,,,,TBC9B_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp131641_c0_seq3,727,45.2545,0.40399632,0,0,,4.00E-41,B1AVH7,TBC1 domain family member 2A,TBC1 domain family member 2A,GO:0005097; GO:0030054; GO:0016023; GO:0031410; GO:0005634; GO:0005543,Rab GTPase activator activity; cell junction; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; nucleus; phospholipid binding,PF00169;PF00566;,,,2.00E-14,ruditapes_c23306,,,,,TBD2A_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; positive regulation of GTPase activity [GO:0043547]; regulation of vesicle fusion [GO:0031338] comp131643_c2_seq1,597,34.6734,0.89370697,0,173,,,,,,,,,,,2.00E-14,ruditapes_c17037,,,,,,, comp131644_c0_seq1,1019,39.6467,0.47692922,5972,24197,,4.00E-27,O46581,"Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) (Fragment)","Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) (Fragment)",GO:0004129; GO:0005743,cytochrome-c oxidase activity; mitochondrial inner membrane,PF02936;,,,,,,,,,COX41_THEGE,Theropithecus gelada (Gelada baboon), comp131646_c0_seq1,1018,34.2829,0.33887628,158,160,,6.00E-27,Q7M3Y3,Troponin I (TnI),Troponin I (TnI),GO:0046872; GO:0005861,metal ion binding; troponin complex,PF00992;,,,4.00E-57,ruditapes2_c2041,,,,,TNNI_CHLNI,Chlamys nipponensis akazara (Akazara scallop) (Japanese scallop), comp131646_c2_seq1,236,46.6102,0.79292156,18,23,,,,,,,,,,,1.00E-12,ruditapes_c1951,,,,,,, comp131647_c0_seq1,840,38.8095,0.45662271,298,405,,3.00E-70,Q63ZL2,Homologous-pairing protein 2 homolog (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein),Homologous-pairing protein 2 homolog (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein),GO:0006310; GO:0007126; GO:0005634,DNA recombination; meiosis; nucleus,PF07106;,2.00E-43,CHOYP_CALM.1.50,,,,,,,HOP2_XENLA,Xenopus laevis (African clawed frog),DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321] comp131649_c0_seq1,877,45.7241,0.29366098,74,127,,3.00E-131,A7SE07,Cytosolic Fe-S cluster assembly factor NUBP2 homolog,Cytosolic Fe-S cluster assembly factor NUBP2 homolog,GO:0051539; GO:0005524; GO:0005737; GO:0046872,"4 iron, 4 sulfur cluster binding; ATP binding; cytoplasm; metal ion binding",PF10609;,1.00E-97,CHOYP_BRAFLDRAFT_275293.1.1,,,,,,,NUBP2_NEMVE,Nematostella vectensis (Starlet sea anemone),iron-sulfur cluster assembly [GO:0016226] comp131651_c0_seq1,493,43.2049,0.54275997,11,27,,1.00E-69,P37223,NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40),NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40),GO:0051287; GO:0005737; GO:0004473; GO:0016619; GO:0006108; GO:0046872; GO:0006950,NAD binding; cytoplasm; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity; malate dehydrogenase (oxaloacetate-decarboxylating) activity; malate metabolic process; metal ion binding; response to stress,PF00390;PF03949;,,,,,,,,,MAOX_MESCR,Mesembryanthemum crystallinum (Common ice plant) (Cryophytum crystallinum),malate metabolic process [GO:0006108] comp131651_c2_seq1,793,45.7755,0.45854176,25,71,,1.00E-93,Q8BMF3,"NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)","NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)",GO:0051287; GO:0004473; GO:0016619; GO:0006108; GO:0046872; GO:0005759; GO:0005739; GO:0006090,NAD binding; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity; malate dehydrogenase (oxaloacetate-decarboxylating) activity; malate metabolic process; metal ion binding; mitochondrial matrix; mitochondrion; pyruvate metabolic process,PF00390;PF03949;,3.00E-72,CHOYP_ME3.1.1,3.00E-82,ruditapes_c10834,,,,,MAON_MOUSE,Mus musculus (Mouse),malate metabolic process [GO:0006108]; oxidation-reduction process [GO:0055114]; pyruvate metabolic process [GO:0006090] comp131652_c0_seq1,1059,39.5656,0.66614356,819,2133,,,,,,,,,1.00E-16,CHOYP_contig_033669,,,,,,,,, comp131652_c1_seq1,1175,43.0638,0.33370667,0,7,,,,,,,,,0,CHOYP_CPIPJ_CPIJ007723.4.4,,,,,,,,, comp131652_c1_seq3,1110,43.4234,0.27004901,0,0,,2.00E-133,A2BD83,RNA polymerase II-associated factor 1 homolog,RNA polymerase II-associated factor 1 homolog,GO:0016593; GO:0000993; GO:0000122; GO:0032968; GO:0045944; GO:0006351,"Cdc73/Paf1 complex; RNA polymerase II core binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF03985;,,,,,,,,,PAF1_XENLA,Xenopus laevis (African clawed frog),histone modification [GO:0016570]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp131652_c1_seq4,1062,43.4087,0.26237967,0,0,,1.00E-136,Q6P2Y1,RNA polymerase II-associated factor 1 homolog,RNA polymerase II-associated factor 1 homolog,GO:0016593; GO:0000993; GO:0000122; GO:0032968; GO:0045944; GO:0006351,"Cdc73/Paf1 complex; RNA polymerase II core binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF03985;,6.00E-178,CHOYP_CPIPJ_CPIJ007723.4.4,,,,,,,PAF1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),histone modification [GO:0016570]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp131654_c1_seq1,1312,49.2378,0.97115441,3719,44,,3.00E-36,Q25390,Alpha-scruin,Alpha-scruin,,,PF01344;,,,,,,,,,SCRA_LIMPO,Limulus polyphemus (Atlantic horseshoe crab), comp131660_c0_seq1,1365,33.9927,0.48349504,352,114,,,,,,,,,2.00E-46,CHOYP_contig_048277,1.00E-127,ruditapes_c21602,,,,,,, comp131667_c0_seq1,1198,42.3205,1.13380694,0,33,,2.00E-85,Q9GRC0,Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos),Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos),GO:0005524; GO:0004709; GO:0007292; GO:0007147; GO:0045930,ATP binding; MAP kinase kinase kinase activity; female gamete generation; female meiosis II; negative regulation of mitotic cell cycle,PF00069;,,,,,,,,,MOS_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930] comp131667_c0_seq2,933,41.1576,1.22361559,0,0,,1.00E-16,Q91909,Mast/stem cell growth factor receptor-related protein Kit (EC 2.7.10.1) (Kit-related kinase 1) (xKrk1) (Tyrosine-protein kinase kit),Mast/stem cell growth factor receptor-related protein Kit (EC 2.7.10.1) (Kit-related kinase 1) (xKrk1) (Tyrosine-protein kinase kit),GO:0005524; GO:0016021; GO:0046872; GO:0018108; GO:0005886; GO:0004714; GO:0007169,ATP binding; integral to membrane; metal ion binding; peptidyl-tyrosine phosphorylation; plasma membrane; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;,,,,,,,,,KIT_XENLA,Xenopus laevis (African clawed frog),Fc receptor signaling pathway [GO:0038093]; Kit signaling pathway [GO:0038109] comp131669_c0_seq1,829,44.6321,1.02360966,4,1020,female>male,9.00E-15,Q3SZR9,Tetraspanin-3 (Tspan-3),Tetraspanin-3 (Tspan-3),GO:0016021,integral to membrane,PF00335;,,,3.00E-45,ruditapes_c26359,,,,,TSN3_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166] comp131669_c1_seq1,833,34.3337,0.61284564,18,1528,,,,,,,,,,,1.00E-12,ruditapes_s36821,,,,,,, comp131671_c0_seq1,1893,39.0386,0.53639211,0,0,,3.00E-50,P50919,Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase),Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase),GO:0005737; GO:0006094; GO:0006096; GO:0006098; GO:0004807,cytoplasm; gluconeogenesis; glycolysis; pentose-phosphate shunt; triose-phosphate isomerase activity,PF00121;,1.00E-107,CHOYP_LOC100879250.1.1,,,,,,,TPIS_MYCHR,Mycoplasma hyorhinis,gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098] comp131671_c0_seq3,1862,38.7755,0.52554142,29,221,,4.00E-108,O77458,Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase),Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase),GO:0006094; GO:0019682; GO:0006096; GO:0006098; GO:0004807,gluconeogenesis; glyceraldehyde-3-phosphate metabolic process; glycolysis; pentose-phosphate shunt; triose-phosphate isomerase activity,PF00121;,,,,,,,,,TPIS_DROYA,Drosophila yakuba (Fruit fly),gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098] comp131671_c0_seq4,1841,39.0005,0.55299162,68,128,,2.00E-105,Q5E956,Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase),Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase),GO:0006094; GO:0019682; GO:0006096; GO:0006098; GO:0004807,gluconeogenesis; glyceraldehyde-3-phosphate metabolic process; glycolysis; pentose-phosphate shunt; triose-phosphate isomerase activity,PF00121;,,,,,,,,,TPIS_BOVIN,Bos taurus (Bovine),gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; multicellular organism development [GO:0007275]; pentose-phosphate shunt [GO:0006098] comp131671_c0_seq6,1386,41.7027,0.49410996,0,5,,2.00E-110,Q1MTI4,Triosephosphate isomerase A (TIM-A) (EC 5.3.1.1) (Triose-phosphate isomerase A),Triosephosphate isomerase A (TIM-A) (EC 5.3.1.1) (Triose-phosphate isomerase A),GO:0006094; GO:0006096; GO:0006098; GO:0004807,gluconeogenesis; glycolysis; pentose-phosphate shunt; triose-phosphate isomerase activity,PF00121;,4.00E-105,CHOYP_LOC100879250.1.1,6.00E-50,ruditapes_c922,,,,,TPISA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098] comp131674_c0_seq1,974,43.7372,0.60221095,0,0,,2.00E-105,Q80TE7,Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1),Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1),GO:0030054; GO:0005737; GO:0014069; GO:0045211,cell junction; cytoplasm; postsynaptic density; postsynaptic membrane,PF13855;PF00595;,4.00E-122,CHOYP_LRRC7.1.1,,,,,,,LRRC7_MOUSE,Mus musculus (Mouse), comp131674_c0_seq2,1021,43.3888,0.58483604,0,0,,7.00E-19,Q01513,Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase),Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase),GO:0005524; GO:0004016; GO:0035556; GO:0000287,ATP binding; adenylate cyclase activity; intracellular signal transduction; magnesium ion binding,PF08509;PF00211;PF13855;PF00481;,5.00E-122,CHOYP_LRRC7.1.1,,,,,,,CYAA_PODAS,Podospora anserina (Pleurage anserina),intracellular signal transduction [GO:0035556] comp131674_c0_seq4,756,42.1958,0.69372183,0,0,,4.00E-09,Q8AVS8,Leucine-rich repeat-containing protein 59,Leucine-rich repeat-containing protein 59,GO:0005789; GO:0016021; GO:0005635,endoplasmic reticulum membrane; integral to membrane; nuclear envelope,PF13855;,,,,,,,,,LRC59_XENLA,Xenopus laevis (African clawed frog), comp131674_c1_seq2,668,50.8982,0.55587993,0,0,,1.00E-09,Q9ULM6,CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase),CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase),GO:0030014; GO:0003723; GO:0005829; GO:0043928; GO:0035195; GO:0046872; GO:0070966; GO:0000289; GO:0005634; GO:0004535; GO:0008284; GO:0010606; GO:2000327; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; RNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene silencing by miRNA; metal ion binding; nuclear-transcribed mRNA catabolic process, no-go decay; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; poly(A)-specific ribonuclease activity; positive regulation of cell proliferation; positive regulation of cytoplasmic mRNA processing body assembly; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF03372;PF13855;,,,,,,,,,CNOT6_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131679_c0_seq1,290,48.9655,0.63613634,13,28,,2.00E-07,Q7S2H8,Mitochondrial thiamine pyrophosphate carrier 1,Mitochondrial thiamine pyrophosphate carrier 1,GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,,,,,,,,,TPC1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),translation [GO:0006412]; transmembrane transport [GO:0055085] comp131679_c1_seq1,499,39.479,0.57018682,0,0,,2.00E-12,Q58DS3,Solute carrier family 25 member 35,Solute carrier family 25 member 35,GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,4.00E-30,CHOYP_M2OM.1.1,,,,,,,S2535_BOVIN,Bos taurus (Bovine),translation [GO:0006412]; transport [GO:0006810] comp131679_c1_seq4,789,41.4449,0.57046306,0,0,,2.00E-99,Q02978,Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute carrier family 25 member 11),Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute carrier family 25 member 11),GO:0006094; GO:0005887; GO:0005743; GO:0015367; GO:0044281,gluconeogenesis; integral to plasma membrane; mitochondrial inner membrane; oxoglutarate:malate antiporter activity; small molecule metabolic process,PF00153;,,,,,,,,,M2OM_HUMAN,Homo sapiens (Human),gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; translation [GO:0006412]; transport [GO:0006810] comp131681_c0_seq1,444,43.6937,0.43756367,0,6,,7.00E-07,B8LCD8,NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase),NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase),GO:0016853; GO:0046872; GO:0000166,isomerase activity; metal ion binding; nucleotide binding,PF03853;,,,,,,,,,NNRE_THAPS,Thalassiosira pseudonana (Marine diatom) (Cyclotella nana), comp131681_c0_seq2,1151,41.7029,0.5288233,54,86,,3.00E-75,Q96F86,Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1),Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1),GO:0003723; GO:0000932; GO:0005829; GO:0043928; GO:0010467,RNA binding; cytoplasmic mRNA processing body; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene expression,PF09532;PF12701;PF03853;,2.00E-26,CHOYP_EDC3.1.1,,,,,,,EDC3_HUMAN,Homo sapiens (Human),cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928] comp131683_c0_seq1,1397,37.8669,0.99924199,1287,0,,5.00E-67,Q61241,Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A),Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A),GO:0005524; GO:0001669; GO:0000287; GO:0031514; GO:0007275; GO:0004674; GO:0007286,ATP binding; acrosomal vesicle; magnesium ion binding; motile cilium; multicellular organismal development; protein serine/threonine kinase activity; spermatid development,PF00069;,,,,,,,,,TSSK1_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] comp131686_c0_seq1,891,29.9663,0.3539687,134,2418,,,,,,,,,,,1.00E-19,ruditapes_c4729,,,,,,, comp131689_c0_seq1,1340,37.3134,0.90533879,3,23,,5.00E-13,P32241,Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1),Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1),GO:0007187; GO:0005737; GO:0007586; GO:0006955; GO:0005887; GO:0006936; GO:0005634; GO:0008284; GO:0007268; GO:0004999,"G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; cytoplasm; digestion; immune response; integral to plasma membrane; muscle contraction; nucleus; positive regulation of cell proliferation; synaptic transmission; vasoactive intestinal polypeptide receptor activity",PF00002;PF02793;,5.00E-15,CHOYP_LOC100718340.1.1,,,,,,,VIPR1_HUMAN,Homo sapiens (Human),"cell surface receptor signaling pathway [GO:0007166]; chemical synaptic transmission [GO:0007268]; digestion [GO:0007586]; G-protein coupled receptor signaling pathway [GO:0007186]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; immune response [GO:0006955]; muscle contraction [GO:0006936]; positive regulation of cell proliferation [GO:0008284]" comp131689_c0_seq3,1269,37.1946,0.91804521,0,8,,6.00E-15,P97751,Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1),Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1),GO:0016021; GO:0005886; GO:0004999,integral to membrane; plasma membrane; vasoactive intestinal polypeptide receptor activity,PF00002;PF02793;,,,3.00E-16,ruditapes_c11349,,,,,VIPR1_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166] comp131692_c0_seq1,2593,42.7304,0.3301903,59,77,,0,P42232,Signal transducer and activator of transcription 5B,Signal transducer and activator of transcription 5B,GO:0006103; GO:0060397; GO:0048541; GO:0000979; GO:0033077; GO:0043029; GO:0000255; GO:0005509; GO:0006101; GO:0006600; GO:0046449; GO:0005829; GO:0046543; GO:0046544; GO:0006631; GO:0007565; GO:0006549; GO:0007595; GO:0019915; GO:0001553; GO:0001779; GO:0043066; GO:0045647; GO:0005634; GO:0006107; GO:0045579; GO:0042104; GO:0045588; GO:0050729; GO:0045086; GO:0045931; GO:0040018; GO:0032825; GO:0045954; GO:0032819; GO:0045944; GO:0042448; GO:0038161; GO:0030155; GO:0030856; GO:0019218; GO:0032355; GO:0070672; GO:0070669; GO:0070670; GO:0003700; GO:0004871; GO:0006105; GO:0019530; GO:0006351; GO:0006573,"2-oxoglutarate metabolic process; JAK-STAT cascade involved in growth hormone signaling pathway; Peyer's patch development; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation in thymus; T cell homeostasis; allantoin metabolic process; calcium ion binding; citrate metabolic process; creatine metabolic process; creatinine metabolic process; cytosol; development of secondary female sexual characteristics; development of secondary male sexual characteristics; fatty acid metabolic process; female pregnancy; isoleucine metabolic process; lactation; lipid storage; luteinization; natural killer cell differentiation; negative regulation of apoptotic process; negative regulation of erythrocyte differentiation; nucleus; oxaloacetate metabolic process; positive regulation of B cell differentiation; positive regulation of activated T cell proliferation; positive regulation of gamma-delta T cell differentiation; positive regulation of inflammatory response; positive regulation of interleukin-2 biosynthetic process; positive regulation of mitotic cell cycle; positive regulation of multicellular organism growth; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell proliferation; positive regulation of transcription from RNA polymerase II promoter; progesterone metabolic process; prolactin signaling pathway; regulation of cell adhesion; regulation of epithelial cell differentiation; regulation of steroid metabolic process; response to estradiol stimulus; response to interleukin-15; response to interleukin-2; response to interleukin-4; sequence-specific DNA binding transcription factor activity; signal transducer activity; succinate metabolic process; taurine metabolic process; transcription, DNA-dependent; valine metabolic process",PF00017;PF01017;PF02864;PF02865;,,,5.00E-16,ruditapes_c23158,,,,,STA5B_MOUSE,Mus musculus (Mouse),2-oxoglutarate metabolic process [GO:0006103]; acute-phase response [GO:0006953]; allantoin metabolic process [GO:0000255]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; citrate metabolic process [GO:0006101]; creatine metabolic process [GO:0006600]; creatinine metabolic process [GO:0046449]; cytokine-mediated signaling pathway [GO:0019221]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; fatty acid metabolic process [GO:0006631]; female pregnancy [GO:0007565]; isoleucine metabolic process [GO:0006549]; JAK-STAT cascade [GO:0007259]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; liver development [GO:0001889]; luteinization [GO:0001553]; mast cell migration [GO:0097531]; natural killer cell differentiation [GO:0001779]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; oxaloacetate metabolic process [GO:0006107]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; progesterone metabolic process [GO:0042448]; prolactin signaling pathway [GO:0038161]; regulation of cell adhesion [GO:0030155]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to lipopolysaccharide [GO:0032496]; sex differentiation [GO:0007548]; succinate metabolic process [GO:0006105]; taurine metabolic process [GO:0019530]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; valine metabolic process [GO:0006573] comp131695_c0_seq3,1167,46.7009,0.86534898,0,50,,6.00E-17,Q62009,Periostin (PN) (Osteoblast-specific factor 2) (OSF-2),Periostin (PN) (Osteoblast-specific factor 2) (OSF-2),GO:0005794; GO:0007155; GO:0030198; GO:0008201; GO:0005578; GO:0008593; GO:0009888,Golgi apparatus; cell adhesion; extracellular matrix organization; heparin binding; proteinaceous extracellular matrix; regulation of Notch signaling pathway; tissue development,PF02469;,,,,,,,,,POSTN_MOUSE,Mus musculus (Mouse),bone regeneration [GO:1990523]; cell adhesion [GO:0007155]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vitamin K [GO:0071307]; extracellular matrix organization [GO:0030198]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neuron projection extension [GO:1990138]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of Notch signaling pathway [GO:0008593]; regulation of systemic arterial blood pressure [GO:0003073]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to muscle activity [GO:0014850]; tissue development [GO:0009888] comp131698_c0_seq3,1464,38.2514,0.56318021,7,19,,,,,,,,,3.00E-12,CHOYP_GPBP1.1.1,,,,,,,,, comp131699_c0_seq1,1313,42.2696,0.48484557,246,2375,,8.00E-49,A4IGH4,tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4 (WD repeat-containing protein 4),tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4 (WD repeat-containing protein 4),GO:0036265; GO:0005634; GO:0006400,RNA (guanine-N7)-methylation; nucleus; tRNA modification,,,,,,,,,,WDR4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]; tRNA modification [GO:0006400] comp131700_c0_seq2,1257,33.6516,0.61928882,72,205,,2.00E-37,P17141,Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein),Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein),GO:0003677; GO:0007281; GO:0007275; GO:0005634; GO:0006355; GO:0007283; GO:0006351; GO:0008270,"DNA binding; germ cell development; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZFP37_MOUSE,Mus musculus (Mouse),"germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp131702_c0_seq1,774,35.0129,0.606214,79,921,,2.00E-07,Q28EE8,Protein SREK1IP1,Protein SREK1IP1,GO:0008380; GO:0006397; GO:0003676; GO:0008270,RNA splicing; mRNA processing; nucleic acid binding; zinc ion binding,,,,5.00E-29,ruditapes_c20998,,,,,SR1IP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp131703_c0_seq1,1060,40.3774,0.68116773,27,48,,3.00E-88,Q921L8,Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11),Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11),GO:0000139; GO:0016021; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,1.00E-27,CHOYP_GALT9.1.1,,,,,,,GLT11_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593] comp131708_c0_seq2,740,44.3243,0.90930554,0,46,,,,,,,,,,,2.00E-52,ruditapes_c8626,,,,,,, comp131710_c0_seq1,2357,37.8023,0.91289215,1188,0,,4.00E-111,Q9LDU6,7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Protein DWARF 5) (Sterol Delta(7)-reductase),7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Protein DWARF 5) (Sterol Delta(7)-reductase),GO:0047598; GO:0005794; GO:0016132; GO:0006695; GO:0005789; GO:0016021; GO:0005886; GO:0009918,7-dehydrocholesterol reductase activity; Golgi apparatus; brassinosteroid biosynthetic process; cholesterol biosynthetic process; endoplasmic reticulum membrane; integral to membrane; plasma membrane; sterol delta7 reductase activity,PF01222;,8.00E-41,CHOYP_LOC100636367.1.1,,,,,,,ST7R_ARATH,Arabidopsis thaliana (Mouse-ear cress),brassinosteroid biosynthetic process [GO:0016132]; cholesterol biosynthetic process [GO:0006695] comp131711_c0_seq1,1205,36.0166,0.74373257,13,335,,4.00E-24,A5A7I8,Calcium-dependent protein kinase 5 (CDPK 5) (StCDPK5) (EC 2.7.11.1),Calcium-dependent protein kinase 5 (CDPK 5) (StCDPK5) (EC 2.7.11.1),GO:0005524; GO:0005509; GO:0005886; GO:0004674,ATP binding; calcium ion binding; plasma membrane; protein serine/threonine kinase activity,PF13499;PF00069;,,,1.00E-26,ruditapes_c28633,,,,,CDPK5_SOLTU,Solanum tuberosum (Potato), comp131711_c0_seq2,983,37.1312,0.86019261,24,311,,2.00E-50,P25071,Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3),Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3),GO:0005509; GO:0009506; GO:0009646; GO:0009652; GO:0005774,calcium ion binding; plasmodesma; response to absence of light; thigmotropism; vacuolar membrane,PF13499;,1.00E-122,CHOYP_CALM.42.50,3.00E-141,ruditapes_c3243,4.00E-127,DW713885.p.cg.6,6,,CML12_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to absence of light [GO:0009646]; response to mechanical stimulus [GO:0009612]; thigmotropism [GO:0009652] comp131711_c0_seq3,545,40.5505,1.00100337,0,15,,1.00E-101,Q8STF0,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,9.00E-147,CHOYP_LOC100533341.1.1,2.00E-145,ruditapes_c2436,4.00E-148,CD526833.p.cg.6,8,,CALM_STRIE,Strongylocentrotus intermedius (Sea urchin), comp131715_c0_seq1,4661,41.8151,0.90602145,3849,11,male>female,4.00E-65,Q5TTP0,WD repeat-containing protein on Y chromosome (WD40 Y),WD repeat-containing protein on Y chromosome (WD40 Y),GO:0005509,calcium ion binding,PF00400;,1.00E-41,CHOYP_LOC100376720.1.1,,,,,,,WDY_ANOGA,Anopheles gambiae (African malaria mosquito), comp131720_c0_seq1,1543,39.2741,0.86441492,4,9256,female>male,3.00E-65,P26256,Annexin-B12 (Annexin XII) (Annexin-12),Annexin-B12 (Annexin XII) (Annexin-12),GO:0005509; GO:0005544,calcium ion binding; calcium-dependent phospholipid binding,PF00191;,,,,,,,,,ANX12_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata), comp131725_c0_seq2,922,41.2148,0.83988269,55,108,,2.00E-12,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp131726_c0_seq1,1966,37.8942,0.40144038,3592,28340,,5.00E-162,B5FZ19,Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (eIF-3-beta) (eIF3 p36),Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (eIF-3-beta) (eIF3 p36),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity,PF00400;,1.00E-164,CHOYP_EIF3I.1.1,0,ruditapes2_c4295,,,,,EIF3I_TAEGU,Taeniopygia guttata (Zebra finch) (Poephila guttata),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp131730_c0_seq1,892,38.565,0.60631151,26,141,,4.00E-54,O15116,U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm),U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm),GO:0003723; GO:0000375; GO:0005829; GO:0043928; GO:0071044; GO:0006397; GO:0005634; GO:0030529,"RNA binding; RNA splicing, via transesterification reactions; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; histone mRNA catabolic process; mRNA processing; nucleus; ribonucleoprotein complex",PF01423;,3.00E-66,CHOYP_LOC100369712.1.1,,,,,,,LSM1_HUMAN,Homo sapiens (Human),"deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; histone mRNA catabolic process [GO:0071044]; mRNA processing [GO:0006397]; negative regulation of neuron differentiation [GO:0045665]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; stem cell population maintenance [GO:0019827]" comp131730_c0_seq2,736,38.8587,0.5816901,0,8,,2.00E-46,O15116,U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm),U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm),GO:0003723; GO:0000375; GO:0005829; GO:0043928; GO:0071044; GO:0006397; GO:0005634; GO:0030529,"RNA binding; RNA splicing, via transesterification reactions; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; histone mRNA catabolic process; mRNA processing; nucleus; ribonucleoprotein complex",PF01423;,,,,,,,,,LSM1_HUMAN,Homo sapiens (Human),"deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; histone mRNA catabolic process [GO:0071044]; mRNA processing [GO:0006397]; negative regulation of neuron differentiation [GO:0045665]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; stem cell population maintenance [GO:0019827]" comp131737_c1_seq2,952,33.5084,0.30471656,0,0,,2.00E-06,Q9D305,THAP domain-containing protein 2,THAP domain-containing protein 2,GO:0003677; GO:0046872,DNA binding; metal ion binding,PF05485;,,,,,,,,,THAP2_MOUSE,Mus musculus (Mouse), comp131737_c1_seq4,1019,33.6605,0.35182153,0,46,,1.00E-06,Q9D305,THAP domain-containing protein 2,THAP domain-containing protein 2,GO:0003677; GO:0046872,DNA binding; metal ion binding,PF05485;,,,,,,,,,THAP2_MOUSE,Mus musculus (Mouse), comp131748_c0_seq1,938,40.4051,0.26670105,27,6,,7.00E-12,Q95LI3,Zinc finger Y-chromosomal protein,Zinc finger Y-chromosomal protein,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF04704;,,,,,,,,,ZFY_BOVIN,Bos taurus (Bovine),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131749_c0_seq1,727,42.7785,0.21345437,24,26,,3.00E-50,Q62388,Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),GO:0016303; GO:0005524; GO:0003677; GO:0000077; GO:0006975; GO:0006281; GO:0004677; GO:0031572; GO:0007420; GO:0007050; GO:0071480; GO:0000781; GO:0016023; GO:0007507; GO:0071044; GO:0016572; GO:0008630; GO:0042159; GO:0007094; GO:0030889; GO:0051402; GO:0005654; GO:0048599; GO:0018105; GO:0043517; GO:0043525; GO:0002331; GO:0047485; GO:0004674; GO:0090399; GO:0010212; GO:0001756; GO:0005819; GO:0000723,"1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA damage checkpoint; DNA damage induced protein phosphorylation; DNA repair; DNA-dependent protein kinase activity; G2 DNA damage checkpoint; brain development; cell cycle arrest; cellular response to gamma radiation; chromosome, telomeric region; cytoplasmic membrane-bounded vesicle; heart development; histone mRNA catabolic process; histone phosphorylation; intrinsic apoptotic signaling pathway in response to DNA damage; lipoprotein catabolic process; mitotic spindle assembly checkpoint; negative regulation of B cell proliferation; neuron apoptotic process; nucleoplasm; oocyte development; peptidyl-serine phosphorylation; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of neuron apoptotic process; pre-B cell allelic exclusion; protein N-terminus binding; protein serine/threonine kinase activity; replicative senescence; response to ionizing radiation; somitogenesis; spindle; telomere maintenance",PF02259;PF02260;PF00454;PF11640;,,,,,,,,,ATM_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to nitrosative stress [GO:0071500]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; establishment of RNA localization to telomere [GO:0097694]; female gamete generation [GO:0007292]; heart development [GO:0007507]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lipoprotein catabolic process [GO:0042159]; meiotic telomere clustering [GO:0045141]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of telomere capping [GO:1904354]; negative regulation of TORC1 signaling [GO:1904262]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; replicative senescence [GO:0090399]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; signal transduction involved in mitotic G2 DNA damage checkpoint [GO:0072434]; somitogenesis [GO:0001756]; telomere maintenance via telomerase [GO:0007004]; V(D)J recombination [GO:0033151]" comp131751_c0_seq1,1575,46.0952,0.60299994,79,64,,1.00E-72,Q75NR7,"ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RecQ protein-like 4)","ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RecQ protein-like 4)",GO:0005524; GO:0008026; GO:0006310; GO:0006260; GO:0005737; GO:0045875; GO:0003676; GO:0005634; GO:0043473; GO:0008284; GO:0048705; GO:0008270,ATP binding; ATP-dependent helicase activity; DNA recombination; DNA replication; cytoplasm; negative regulation of sister chromatid cohesion; nucleic acid binding; nucleus; pigmentation; positive regulation of cell proliferation; skeletal system morphogenesis; zinc ion binding,PF00270;PF11719;PF00271;PF00098;,2.00E-59,CHOYP_LOC567383.1.1,,,,,,,RECQ4_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; negative regulation of sister chromatid cohesion [GO:0045875]; pigmentation [GO:0043473]; positive regulation of cell proliferation [GO:0008284]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705] comp131751_c2_seq1,304,46.7105,0.79667328,8,6,,2.00E-15,Q9VGI8,Bloom syndrome protein homolog (Dmblm) (EC 3.6.4.12) (Mutagen-sensitive protein 309) (RecQ helicase homolog),Bloom syndrome protein homolog (Dmblm) (EC 3.6.4.12) (Bloom syndrome helicase ortholog) (Mutagen-sensitive protein 309) (RecQ helicase homolog),GO:0005524; GO:0043140; GO:0006260; GO:0000733; GO:0000731; GO:0000403; GO:0045003; GO:1901291; GO:0005634; GO:0007131; GO:0000732,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA replication; DNA strand renaturation; DNA synthesis involved in DNA repair; Y-form DNA binding; double-strand break repair via synthesis-dependent strand annealing; negative regulation of double-strand break repair via single-strand annealing; nucleus; reciprocal meiotic recombination; strand displacement,PF00270;PF00271;PF00570;PF16124;PF09382;,4.00E-40,CHOYP_LOC567383.1.1,,,,,,,BLM_DROME,Drosophila melanogaster (Fruit fly),cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; reciprocal meiotic recombination [GO:0007131]; strand displacement [GO:0000732] comp131757_c0_seq1,840,39.1667,0.85512662,15,248,,3.00E-18,Q9BTX7,Alpha-tocopherol transfer protein-like,Alpha-tocopherol transfer protein-like,GO:0005622; GO:0005215,intracellular; transporter activity,PF00650;PF03765;,,,,,,,,,TTPAL_HUMAN,Homo sapiens (Human), comp131772_c0_seq1,1317,47.1526,0.53317183,62,34,,7.00E-67,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,4.00E-42,CHOYP_UNC22.2.2,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp131772_c1_seq1,737,46.9471,0.83883416,0,0,,5.00E-22,A2RUH7,Myosin-binding protein H-like,Myosin-binding protein H-like,,,PF00041;PF07679;,,,,,,,,,MBPHL_HUMAN,Homo sapiens (Human), comp131772_c1_seq2,933,47.2669,0.74938368,18,36,,4.00E-26,Q14896,"Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)","Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)",GO:0001671; GO:0014705; GO:0060048; GO:0007155; GO:0005829; GO:0046872; GO:0030049; GO:0017022; GO:0031034; GO:0002027; GO:0032971; GO:0006942; GO:0045214; GO:0005863; GO:0008307; GO:0031432; GO:0055010,ATPase activator activity; C zone; cardiac muscle contraction; cell adhesion; cytosol; metal ion binding; muscle filament sliding; myosin binding; myosin filament assembly; regulation of heart rate; regulation of muscle filament sliding; regulation of striated muscle contraction; sarcomere organization; striated muscle myosin thick filament; structural constituent of muscle; titin binding; ventricular cardiac muscle tissue morphogenesis,PF00041;PF07679;,,,,,,,,,MYPC3_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] comp131777_c1_seq1,1378,38.1713,0.50161533,0,0,,1.00E-107,Q3ZBG6,Protein unc-50 homolog,Protein unc-50 homolog,GO:0000139; GO:0003723; GO:0016021; GO:0005637; GO:0015031,Golgi membrane; RNA binding; integral to membrane; nuclear inner membrane; protein transport,PF05216;,,,,,,,,,UNC50_BOVIN,Bos taurus (Bovine),protein transport [GO:0015031]; transport [GO:0006810] comp131777_c1_seq4,1345,38.3643,0.48824161,0,0,,1.00E-107,Q3ZBG6,Protein unc-50 homolog,Protein unc-50 homolog,GO:0000139; GO:0003723; GO:0016021; GO:0005637; GO:0015031,Golgi membrane; RNA binding; integral to membrane; nuclear inner membrane; protein transport,PF05216;,4.00E-105,CHOYP_UNC50.1.1,,,,,,,UNC50_BOVIN,Bos taurus (Bovine),protein transport [GO:0015031]; transport [GO:0006810] comp131777_c1_seq8,1142,38.2662,0.5046892,0,0,,,,,,,,,2.00E-82,CHOYP_UNC50.1.1,,,,,,,,, comp131780_c0_seq1,1127,41.26,0.83794591,2,0,,7.00E-76,Q9VN27,"Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase)","Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase)",GO:0016874; GO:0009107; GO:0033819; GO:0005739; GO:0016415; GO:0009249,ligase activity; lipoate biosynthetic process; lipoyl(octanoyl) transferase activity; mitochondrion; octanoyltransferase activity; protein lipoylation,PF03099;,,,,,,,,,LIPT2_DROME,Drosophila melanogaster (Fruit fly),lipoate biosynthetic process [GO:0009107]; protein lipoylation [GO:0009249] comp131783_c0_seq1,1098,41.439,0.36099655,0,0,,7.00E-34,P57716,Nicastrin,Nicastrin,GO:0005794; GO:0007219; GO:0042098; GO:0050435; GO:0004175; GO:0005783; GO:0050673; GO:0005887; GO:0005765; GO:0042470; GO:0006509; GO:0002262; GO:0043085; GO:0016485,Golgi apparatus; Notch signaling pathway; T cell proliferation; beta-amyloid metabolic process; endopeptidase activity; endoplasmic reticulum; epithelial cell proliferation; integral to plasma membrane; lysosomal membrane; melanosome; membrane protein ectodomain proteolysis; myeloid cell homeostasis; positive regulation of catalytic activity; protein processing,PF05450;,,,,,,,,,NICA_MOUSE,Mus musculus (Mouse),beta-amyloid metabolic process [GO:0050435]; epithelial cell proliferation [GO:0050673]; membrane protein ectodomain proteolysis [GO:0006509]; myeloid cell homeostasis [GO:0002262]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]; T cell proliferation [GO:0042098] comp131783_c0_seq4,2402,42.8809,0.38980168,0,0,,3.00E-142,Q92542,Nicastrin,Nicastrin,GO:0005794; GO:0007220; GO:0007219; GO:0042098; GO:0042987; GO:0097190; GO:0050435; GO:0004175; GO:0005783; GO:0050673; GO:0005887; GO:0005765; GO:0042470; GO:0006509; GO:0031293; GO:0002262; GO:0048011; GO:0043065; GO:0043085; GO:0016485,Golgi apparatus; Notch receptor processing; Notch signaling pathway; T cell proliferation; amyloid precursor protein catabolic process; apoptotic signaling pathway; beta-amyloid metabolic process; endopeptidase activity; endoplasmic reticulum; epithelial cell proliferation; integral to plasma membrane; lysosomal membrane; melanosome; membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; myeloid cell homeostasis; neurotrophin TRK receptor signaling pathway; positive regulation of apoptotic process; positive regulation of catalytic activity; protein processing,PF05450;,1.00E-19,CHOYP_BRAFLDRAFT_115392.1.1,,,,,,,NICA_HUMAN,Homo sapiens (Human),amyloid precursor protein catabolic process [GO:0042987]; beta-amyloid metabolic process [GO:0050435]; ephrin receptor signaling pathway [GO:0048013]; epithelial cell proliferation [GO:0050673]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]; proteolysis [GO:0006508]; T cell proliferation [GO:0042098] comp131783_c0_seq5,2272,42.6937,0.37713148,0,0,,8.00E-66,Q9VC27,Nicastrin,Nicastrin,GO:0007220; GO:0007219; GO:0045463; GO:0007010; GO:0016021; GO:0046331; GO:0006509; GO:0008594; GO:0016485; GO:0045314,Notch receptor processing; Notch signaling pathway; R8 cell development; cytoskeleton organization; integral to membrane; lateral inhibition; membrane protein ectodomain proteolysis; photoreceptor cell morphogenesis; protein processing; regulation of compound eye photoreceptor development,PF05450;,1.00E-19,CHOYP_BRAFLDRAFT_115392.1.1,,,,,,,NICA_DROME,Drosophila melanogaster (Fruit fly),cytoskeleton organization [GO:0007010]; lateral inhibition [GO:0046331]; membrane protein ectodomain proteolysis [GO:0006509]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; photoreceptor cell morphogenesis [GO:0008594]; protein processing [GO:0016485]; R8 cell development [GO:0045463]; regulation of compound eye photoreceptor development [GO:0045314] comp131787_c1_seq2,928,42.6724,0.45087412,58,407,,5.00E-13,Q9JIQ3,"Diablo homolog, mitochondrial (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac)","Diablo homolog, mitochondrial (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac)",GO:0035631; GO:0008635; GO:0009898; GO:0008631; GO:0005758; GO:0051402,CD40 receptor complex; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; internal side of plasma membrane; intrinsic apoptotic signaling pathway in response to oxidative stress; mitochondrial intermembrane space; neuron apoptotic process,PF09057;,,,,,,,,,DBLOH_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065] comp131792_c0_seq2,640,50.1562,0.67295444,2,0,,2.00E-17,Q5XIR4,Coiled-coil domain-containing protein 33,Coiled-coil domain-containing protein 33,,,PF00168;,5.00E-11,CHOYP_BRAFLDRAFT_118966.1.1,,,,,,,CCD33_RAT,Rattus norvegicus (Rat), comp131795_c0_seq1,974,40.2464,0.46935223,3,0,,5.00E-18,Q75JN1,Probable serine/threonine-protein kinase ifkC (EC 2.7.11.1) (Initiation factor kinase C),Probable serine/threonine-protein kinase ifkC (EC 2.7.11.1) (Initiation factor kinase C),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF12745;PF00069;PF05773;,,,,,,,,,IFKC_DICDI,Dictyostelium discoideum (Slime mold), comp131795_c2_seq1,984,40.9553,0.43764856,48,110,,1.00E-61,Q9NZJ5,Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK),Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK),GO:0005524; GO:0006983; GO:0032933; GO:0006919; GO:0006987; GO:0030282; GO:0019722; GO:0002063; GO:0031018; GO:0005789; GO:0007029; GO:0004694; GO:0045444; GO:0030073; GO:0048009; GO:0016021; GO:0007595; GO:0031642; GO:0032057; GO:0032092; GO:0009967; GO:0046777; GO:0051260; GO:0019217; GO:0006412; GO:0006926,ATP binding; ER overload response; SREBP signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of signaling protein activity involved in unfolded protein response; bone mineralization; calcium-mediated signaling; chondrocyte development; endocrine pancreas development; endoplasmic reticulum membrane; endoplasmic reticulum organization; eukaryotic translation initiation factor 2alpha kinase activity; fat cell differentiation; insulin secretion; insulin-like growth factor receptor signaling pathway; integral to membrane; lactation; negative regulation of myelination; negative regulation of translational initiation in response to stress; positive regulation of protein binding; positive regulation of signal transduction; protein autophosphorylation; protein homooligomerization; regulation of fatty acid metabolic process; translation; virus-infected cell apoptotic process,PF00069;,1.00E-33,CHOYP_BRAFLDRAFT_98591.1.1,,,,,,,E2AK3_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; calcium-mediated signaling [GO:0019722]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; chondrocyte development [GO:0002063]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin secretion [GO:0030073]; negative regulation of myelination [GO:0031642]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation in response to stress [GO:0032057]; ossification [GO:0001503]; peptidyl-serine phosphorylation [GO:0018105]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; skeletal system development [GO:0001501] comp131803_c0_seq1,623,35.4735,0.36315358,81,184,,9.00E-30,Q9D0S9,"Histidine triad nucleotide-binding protein 2, mitochondrial (HINT-2) (EC 3.-.-.-) (HINT-3)","Histidine triad nucleotide-binding protein 2, mitochondrial (HINT-2) (EC 3.-.-.-) (HINT-3)",GO:0006915; GO:0016787; GO:0005739; GO:0000166; GO:0006694,apoptotic process; hydrolase activity; mitochondrion; nucleotide binding; steroid biosynthetic process,PF01230;,8.00E-15,CHOYP_LOC100691034.2.2,,,,,,,HINT2_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; steroid biosynthetic process [GO:0006694] comp131803_c0_seq3,321,44.5483,0.2522547,36,173,,8.00E-11,Q9ZDL1,Uncharacterized HIT-like protein RP317,Uncharacterized HIT-like protein RP317,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF01230;,,,,,,,,,YHIT_RICPR,Rickettsia prowazekii (strain Madrid E), comp131804_c1_seq1,614,45.114,0.4187629,14,9,,9.00E-60,Q08AX9,Uncharacterized protein KIAA1841 homolog,Uncharacterized protein KIAA1841 homolog,,,PF11822;,1.00E-56,CHOYP_K1841.1.1,,,,,,,K1841_XENLA,Xenopus laevis (African clawed frog), comp131808_c0_seq1,1593,34.8399,0.58342507,2617,13207,,2.00E-87,P40307,Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I),Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0014070; GO:0010243; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; response to organic cyclic compound; response to organonitrogen compound; threonine-type endopeptidase activity,PF00227;,5.00E-54,CHOYP_PSMB2.1.1,2.00E-126,ruditapes2_c2247,,,,,PSB2_RAT,Rattus norvegicus (Rat),proteolysis involved in cellular protein catabolic process [GO:0051603]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243] comp131814_c1_seq1,846,40.4255,0.58173158,40,148,,7.00E-26,Q6PFK1,Zinc finger protein 598,Zinc finger protein 598,GO:0008270,zinc ion binding,,,,,,,,,,ZN598_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp131819_c0_seq1,1011,38.2789,0.6001084,43,98,,5.00E-87,B2RYG6,Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (Ubiquitin-specific-processing protease OTUB1),Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (Ubiquitin-specific-processing protease OTUB1),GO:0006281; GO:0019784; GO:0005737; GO:2000780; GO:1901315; GO:0008242; GO:0071108; GO:0006508; GO:0006974; GO:0043130; GO:0004843,DNA repair; NEDD8-specific protease activity; cytoplasm; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; omega peptidase activity; protein K48-linked deubiquitination; proteolysis; response to DNA damage stimulus; ubiquitin binding; ubiquitin-specific protease activity,PF10275;,5.00E-52,CHOYP_OTUB1.1.1,,,,,,,OTUB1_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein K48-linked deubiquitination [GO:0071108] comp131821_c0_seq1,805,40.1242,0.41119285,73,205,,2.00E-64,P22061,Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase),Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase),GO:0005783; GO:0030091; GO:0004719,endoplasmic reticulum; protein repair; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,,6.00E-24,CHOYP_BRAFLDRAFT_284774.3.3,,,,,,,PIMT_HUMAN,Homo sapiens (Human),protein methylation [GO:0006479]; protein repair [GO:0030091] comp131821_c0_seq3,502,42.8287,0.72270402,33,104,,4.00E-50,Q92047,Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase),Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase),GO:0005737; GO:0004719,cytoplasm; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,,2.00E-21,CHOYP_BRAFLDRAFT_284774.3.3,,,,,,,PIMT_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp131825_c1_seq1,627,44.3381,0.39669522,12,14,,2.00E-53,Q9P7V5,Protein transport protein sec72,Protein transport protein sec72,GO:0005086; GO:0006888; GO:0000137; GO:0000138; GO:0005798; GO:0005938; GO:0006886; GO:0005635; GO:0032012,ARF guanyl-nucleotide exchange factor activity; ER to Golgi vesicle-mediated transport; Golgi cis cisterna; Golgi trans cisterna; Golgi-associated vesicle; cell cortex; intracellular protein transport; nuclear envelope; regulation of ARF protein signal transduction,PF16213;PF09324;PF01369;PF12783;,5.00E-132,CHOYP_BIG1.2.3,,,,,,,SEC7B_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; regulation of ARF protein signal transduction [GO:0032012] comp131825_c1_seq3,1069,46.0243,0.40721472,0,0,,4.00E-06,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,4.00E-148,CHOYP_BIG1.3.3,,,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp131825_c1_seq5,2164,42.098,0.43194656,4,0,,0,O46382,Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1),Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1),GO:0005086; GO:0000139; GO:0007030; GO:0005829; GO:0010256; GO:0034259; GO:0030837; GO:0016363; GO:0005730; GO:0048471; GO:0090284; GO:0090303; GO:0034237; GO:0015031; GO:0032012; GO:2000114; GO:0030532; GO:0005802,ARF guanyl-nucleotide exchange factor activity; Golgi membrane; Golgi organization; cytosol; endomembrane system organization; negative regulation of Rho GTPase activity; negative regulation of actin filament polymerization; nuclear matrix; nucleolus; perinuclear region of cytoplasm; positive regulation of protein glycosylation in Golgi; positive regulation of wound healing; protein kinase A regulatory subunit binding; protein transport; regulation of ARF protein signal transduction; regulation of establishment of cell polarity; small nuclear ribonucleoprotein complex; trans-Golgi network,PF16213;PF09324;PF01369;PF12783;,,,,,,,,,BIG1_BOVIN,Bos taurus (Bovine),endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]; vesicle-mediated transport [GO:0016192] comp131828_c1_seq1,1549,43.9638,0.65172688,131,155,,4.00E-138,P23508,Colorectal mutant cancer protein (Protein MCC),Colorectal mutant cancer protein (Protein MCC),GO:0016055; GO:0005737; GO:0090090; GO:0010633; GO:0050680; GO:0005634; GO:0005886; GO:0004872; GO:0007165,Wnt receptor signaling pathway; cytoplasm; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of epithelial cell migration; negative regulation of epithelial cell proliferation; nucleus; plasma membrane; receptor activity; signal transduction,PF10506;,9.00E-32,CHOYP_contig_039932,,,,,,,CRCM_HUMAN,Homo sapiens (Human),establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] comp131832_c1_seq1,656,42.0732,0.34528144,0,0,,1.00E-07,P40657,Putative transcription factor SOX-15 (Sox50E),Putative transcription factor SOX-15 (Sox50E),GO:0003677; GO:0022416; GO:0043066; GO:0008285; GO:0000122; GO:0005634; GO:0006351; GO:0035220,"DNA binding; chaeta development; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent; wing disc development",PF00505;,,,,,,,,,SOX15_DROME,Drosophila melanogaster (Fruit fly),"chaeta development [GO:0022416]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]" comp131832_c1_seq2,1935,41.2403,0.45008557,98,31,,,,,,,,,8.00E-21,CHOYP_LOC100863610.1.1,,,,,,,,, comp131837_c0_seq1,2041,43.998,0.66970797,86,216,,4.00E-16,B4DU55,Zinc finger protein 879,Zinc finger protein 879,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN879_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131837_c1_seq1,984,40.8537,0.92793313,0,0,,2.00E-15,Q9NPA5,"Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)","Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)",GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZF64A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131837_c1_seq2,1228,42.671,0.73493041,0,0,,3.00E-08,Q2EI20,RE1-silencing transcription factor (Neural-restrictive silencer factor),RE1-silencing transcription factor (Neural-restrictive silencer factor),GO:0021785; GO:0021610; GO:0046872; GO:0010629; GO:0045879; GO:0001764; GO:0003676; GO:0005634; GO:0043065; GO:0000981; GO:0060831,branchiomotor neuron axon guidance; facial nerve morphogenesis; metal ion binding; negative regulation of gene expression; negative regulation of smoothened signaling pathway; neuron migration; nucleic acid binding; nucleus; positive regulation of apoptotic process; sequence-specific DNA binding RNA polymerase II transcription factor activity; smoothened signaling pathway involved in dorsal/ventral neural tube patterning,,9.00E-75,CHOYP_LOC100186203.1.1,,,,,,,REST_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"branchiomotor neuron axon guidance [GO:0021785]; facial nerve morphogenesis [GO:0021610]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron migration [GO:0001764]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; transcription, DNA-templated [GO:0006351]" comp131837_c1_seq4,996,40.8635,0.91684909,0,0,,6.00E-10,A2A5K6,Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1),Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1),GO:0000979; GO:0048854; GO:0021895; GO:0080182; GO:0035097; GO:0001701; GO:0046872; GO:0048812; GO:0005634; GO:0050671; GO:0002052; GO:0040029; GO:0051569; GO:0006355; GO:0006351,"RNA polymerase II core promoter sequence-specific DNA binding; brain morphogenesis; cerebral cortex neuron differentiation; histone H3-K4 trimethylation; histone methyltransferase complex; in utero embryonic development; metal ion binding; neuron projection morphogenesis; nucleus; positive regulation of lymphocyte proliferation; positive regulation of neuroblast proliferation; regulation of gene expression, epigenetic; regulation of histone H3-K4 methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,2.00E-30,ruditapes_c19719,,,,,ZN335_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; brain morphogenesis [GO:0048854]; cerebral cortex neuron differentiation [GO:0021895]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; neuron projection morphogenesis [GO:0048812]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neurogenesis [GO:0050769]; regulation of gene expression [GO:0010468]; regulation of gene expression, epigenetic [GO:0040029]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131848_c0_seq1,658,41.4894,1.05702678,0,263,,2.00E-17,Q95332,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (Fragment),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (Fragment),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,2.00E-17,CHOYP_LOC100371248.2.2,,,,,,,BHMT1_PIG,Sus scrofa (Pig),amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086] comp131848_c1_seq1,820,44.7561,0.98141321,1,409,female>male,1.00E-17,O35490,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,5.00E-19,CHOYP_LOC100371248.1.2,,,,,,,BHMT1_MOUSE,Mus musculus (Mouse),amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086] comp13184_c0_seq1,413,42.3729,0.43260442,8,0,,4.00E-14,Q9CR40,Kelch-like protein 28 (BTB/POZ domain-containing protein 5),Kelch-like protein 28 (BTB/POZ domain-containing protein 5),,,PF07707;PF00651;PF01344;,,,,,,,,,KLH28_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp131853_c0_seq1,1456,42.3764,0.62804395,77,39,,6.00E-104,P85298,Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8),Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8),GO:0005100; GO:0005829; GO:0070374; GO:0007264,Rho GTPase activator activity; cytosol; positive regulation of ERK1 and ERK2 cascade; small GTPase mediated signal transduction,PF13716;PF00620;,8.00E-64,CHOYP_ARHGAP8.1.1,,,,,,,RHG08_HUMAN,Homo sapiens (Human),positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp131862_c2_seq1,774,41.6021,0.50898289,19,149,,2.00E-14,Q9CZ92,Centromere protein P (CENP-P),Centromere protein P (CENP-P),GO:0034080; GO:0000775; GO:0005634,"CENP-A containing nucleosome assembly at centromere; chromosome, centromeric region; nucleus",PF13096;,,,,,,,,,CENPP_MOUSE,Mus musculus (Mouse),CENP-A containing nucleosome assembly [GO:0034080] comp131864_c0_seq1,1006,39.4632,0.4175179,332,2080,,1.00E-91,Q9CYH6,Ribosome biogenesis regulatory protein homolog,Ribosome biogenesis regulatory protein homolog,GO:0000794; GO:0005783; GO:0007080; GO:0005730; GO:0042254,condensed nuclear chromosome; endoplasmic reticulum; mitotic metaphase plate congression; nucleolus; ribosome biogenesis,PF04939;,5.00E-83,CHOYP_RHG17.1.2,,,,,,,RRS1_MOUSE,Mus musculus (Mouse),"endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic metaphase plate congression [GO:0007080]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055]" comp131866_c0_seq1,1188,39.8148,0.89283479,547,147,,1.00E-09,Q99946,Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),GO:0030054; GO:0016021; GO:0005886; GO:0009607; GO:0045202,cell junction; integral to membrane; plasma membrane; response to biotic stimulus; synapse,PF04505;,,,,,,,,,PRRT1_HUMAN,Homo sapiens (Human),response to biotic stimulus [GO:0009607] comp131866_c0_seq2,1164,39.433,0.88478838,1522,1,male>female,2.00E-09,Q99946,Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),GO:0030054; GO:0016021; GO:0005886; GO:0009607; GO:0045202,cell junction; integral to membrane; plasma membrane; response to biotic stimulus; synapse,PF04505;,,,,,,,,,PRRT1_HUMAN,Homo sapiens (Human),response to biotic stimulus [GO:0009607] comp131872_c0_seq1,883,46.3194,0.47634038,3,0,,,,,,,,,6.00E-31,CHOYP_LOC100892888.1.1,,,,,,,,, comp131872_c0_seq2,1246,46.1477,0.46760192,26,0,,2.00E-07,Q8MI28,Limbin,Limbin,GO:0060170; GO:0005737; GO:0016021; GO:0005932; GO:0005634; GO:0007224,cilium membrane; cytoplasm; integral to membrane; microtubule basal body; nucleus; smoothened signaling pathway,PF12297;,,,,,,,,,LBN_BOVIN,Bos taurus (Bovine),smoothened signaling pathway [GO:0007224] comp131873_c0_seq1,1118,40.6977,0.32623933,0,0,,5.00E-28,Q4J9D2,Uncharacterized protein Saci_1252,Uncharacterized protein Saci_1252,,,PF01661;,,,,,,,,,Y1252_SULAC,Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770), comp131873_c0_seq2,1264,40.5854,0.31023931,0,0,,1.00E-27,Q97UU4,Uncharacterized protein SSO2899,Uncharacterized protein SSO2899,,,PF01661;,,,,,,,,,Y2899_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2), comp131873_c0_seq3,1120,41.4286,0.2928042,0,0,,2.00E-26,Q8ZXT3,Uncharacterized protein PAE1111,Uncharacterized protein PAE1111,,,PF01661;,,,,,,,,,Y1111_PYRAE,Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827), comp131873_c0_seq5,1262,39.9366,0.34174275,0,0,,3.00E-22,Q8IXQ6,Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein),Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein),GO:0003950; GO:0016477; GO:0005737; GO:0005829; GO:0006302; GO:0005634; GO:0060330,NAD+ ADP-ribosyltransferase activity; cell migration; cytoplasm; cytosol; double-strand break repair; nucleus; regulation of response to interferon-gamma,PF01661;,1.00E-17,CHOYP_PAR14.12.17,,,,,,,PARP9_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330] comp131874_c0_seq1,3223,38.5355,0.48396684,0,0,,0,Q501J6,Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17),Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17),GO:0005524; GO:0008026; GO:0003723; GO:0072358; GO:0030331; GO:0005730; GO:0005634; GO:0033148; GO:0045944; GO:0009791; GO:2001014; GO:0003713; GO:0006351,"ATP binding; ATP-dependent helicase activity; RNA binding; cardiovascular system development; estrogen receptor binding; nucleolus; nucleus; positive regulation of intracellular estrogen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; regulation of skeletal muscle cell differentiation; transcription coactivator activity; transcription, DNA-dependent",PF00270;PF00271;,1.00E-167,CHOYP_LOC100376610.3.3,,,,,,,DDX17_MOUSE,Mus musculus (Mouse),"cardiovascular system development [GO:0072358]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]" comp131874_c0_seq3,2758,40.7542,0.50388099,146,1005,,0,Q501J6,Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17),Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17),GO:0005524; GO:0008026; GO:0003723; GO:0072358; GO:0030331; GO:0005730; GO:0005634; GO:0033148; GO:0045944; GO:0009791; GO:2001014; GO:0003713; GO:0006351,"ATP binding; ATP-dependent helicase activity; RNA binding; cardiovascular system development; estrogen receptor binding; nucleolus; nucleus; positive regulation of intracellular estrogen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; regulation of skeletal muscle cell differentiation; transcription coactivator activity; transcription, DNA-dependent",PF00270;PF00271;,0,CHOYP_LOC100376610.3.3,,,,,,,DDX17_MOUSE,Mus musculus (Mouse),"cardiovascular system development [GO:0072358]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]" comp131874_c0_seq4,3188,38.5508,0.48855835,0,0,,9.00E-154,A7TTT5,ATP-dependent RNA helicase DBP2 (EC 3.6.4.13),ATP-dependent RNA helicase DBP2 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0000184; GO:0005634; GO:0006364,"ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; rRNA processing",PF00270;PF00271;,2.00E-13,CHOYP_DDX46.1.1,,,,,,,DBP2_VANPO,Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]" comp131874_c0_seq6,2347,34.8104,0.51037148,149,495,,,,,,,,,,,2.00E-20,ruditapes2_c404,,,,,,, comp131879_c0_seq1,800,39.875,0.64622933,32,94,,4.00E-73,Q4PRC2,Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform),Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform),GO:0000139; GO:0019752; GO:0030054; GO:0016023; GO:0005829; GO:0004351; GO:0042136; GO:0042734; GO:0030170,Golgi membrane; carboxylic acid metabolic process; cell junction; cytoplasmic membrane-bounded vesicle; cytosol; glutamate decarboxylase activity; neurotransmitter biosynthetic process; presynaptic membrane; pyridoxal phosphate binding,PF00282;,4.00E-27,CHOYP_GADL1.1.1,,,,,,,DCE2_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),carboxylic acid metabolic process [GO:0019752]; neurotransmitter biosynthetic process [GO:0042136] comp131893_c0_seq1,597,36.6834,0.80282152,7,30,,4.00E-21,Q8BV66,Interferon-induced protein 44 (Microtubule-associated protein 44),Interferon-induced protein 44 (Microtubule-associated protein 44),GO:0005737,cytoplasm,PF07534;,,,,,,,,,IFI44_MOUSE,Mus musculus (Mouse), comp131893_c2_seq1,330,36.3636,0.47888171,14,29,,8.00E-06,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,,,,,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp131895_c0_seq1,379,42.2164,0.9047682,1,70,,4.00E-72,Q09332,UDP-glucose:glycoprotein glucosyltransferase (UGT) (dUGT) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase),UDP-glucose:glycoprotein glucosyltransferase (UGT) (dUGT) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase),GO:0003980; GO:0005788; GO:0005635; GO:0006486; GO:0005791,UDP-glucose:glycoprotein glucosyltransferase activity; endoplasmic reticulum lumen; nuclear envelope; protein glycosylation; rough endoplasmic reticulum,PF01501;PF06427;,3.00E-68,CHOYP_UGGG1.1.1,,,,,,,UGGG_DROME,Drosophila melanogaster (Fruit fly),protein glycosylation [GO:0006486] comp131899_c1_seq1,866,40.8776,0.55648341,24,34,,4.00E-100,Q9NZ32,Actin-related protein 10 (Actin-related protein 11) (hARP11),Actin-related protein 10 (Actin-related protein 11) (hARP11),GO:0005737; GO:0005869; GO:0007018,cytoplasm; dynactin complex; microtubule-based movement,PF00022;,2.00E-30,CHOYP_LOC100891502.1.1,,,,,,,ARP10_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp131899_c2_seq1,408,44.6078,0.6918007,9,43,,2.00E-08,Q25381,"Actin, muscle (LPM) (Fragment)","Actin, muscle (LPM) (Fragment)",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,,,,,,,,,ACTM_LYTPI,Lytechinus pictus (Painted sea urchin), comp131903_c0_seq1,774,35.0129,0.79001151,1683,6646,,7.00E-07,Q0MQC8,"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Complex I-AGGG) (CI-AGGG) (NADH-ubiquinone oxidoreductase AGGG subunit)","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Complex I-AGGG) (CI-AGGG) (NADH-ubiquinone oxidoreductase AGGG subunit)",GO:0005747; GO:0055114,mitochondrial respiratory chain complex I; oxidation-reduction process,,,,,,,,,,NDUB2_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),oxidation-reduction process [GO:0055114] comp131907_c0_seq1,765,41.0458,0.49924726,21,118,,3.00E-27,O74761,DNA primase large subunit (EC 2.7.7.-),DNA primase large subunit (EC 2.7.7.-),GO:0051539; GO:0003677; GO:0003896; GO:0005658; GO:0005829; GO:0046872; GO:0000790; GO:1990077; GO:0000723,"4 iron, 4 sulfur cluster binding; DNA binding; DNA primase activity; alpha DNA polymerase:primase complex; cytosol; metal ion binding; nuclear chromatin; primosome complex; telomere maintenance",PF04104;,,,,,,,,,PRI2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),synthesis of RNA primer involved in mitotic DNA replication [GO:1902981] comp131910_c0_seq1,705,42.8369,0.50255918,2,0,,9.00E-40,Q8BTY2,Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7),Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7),GO:0016324; GO:0060117; GO:0016323; GO:0021747; GO:0005737; GO:0005452; GO:0016021; GO:0061299; GO:0046666; GO:0006814; GO:0032420; GO:0015293,apical plasma membrane; auditory receptor cell development; basolateral plasma membrane; cochlear nucleus development; cytoplasm; inorganic anion exchanger activity; integral to membrane; retina vasculature morphogenesis in camera-type eye; retinal cell programmed cell death; sodium ion transport; stereocilium; symporter activity,PF07565;PF00955;,,,,,,,,,S4A7_MOUSE,Mus musculus (Mouse),anion transmembrane transport [GO:0098656]; auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cochlear nucleus development [GO:0021747]; regulation of intracellular pH [GO:0051453]; retinal cell programmed cell death [GO:0046666]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sodium ion transport [GO:0006814]; visual perception [GO:0007601] comp131910_c0_seq2,945,43.0688,0.48328765,13,0,,2.00E-53,Q80ZA5,Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10),Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10),GO:0016323; GO:0005452; GO:0016021; GO:0006885; GO:0006814; GO:0015293,basolateral plasma membrane; inorganic anion exchanger activity; integral to membrane; regulation of pH; sodium ion transport; symporter activity,PF07565;PF00955;,4.00E-46,CHOYP_S4A10.4.4,,,,,,,S4A10_RAT,Rattus norvegicus (Rat),anion transmembrane transport [GO:0098656]; bicarbonate transport [GO:0015701]; nervous system development [GO:0007399]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814] comp131912_c0_seq1,1972,41.785,0.3389975,29,17,,7.00E-80,Q8CJH3,Plexin-B1,Plexin-B1,GO:0005887; GO:0005622; GO:0033689; GO:0048812; GO:0043931; GO:0032321; GO:0050772; GO:0014068; GO:0008360; GO:0051493; GO:0017154; GO:0002116; GO:1900220,integral to plasma membrane; intracellular; negative regulation of osteoblast proliferation; neuron projection morphogenesis; ossification involved in bone maturation; positive regulation of Rho GTPase activity; positive regulation of axonogenesis; positive regulation of phosphatidylinositol 3-kinase cascade; regulation of cell shape; regulation of cytoskeleton organization; semaphorin receptor activity; semaphorin receptor complex; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB1_MOUSE,Mus musculus (Mouse),axon extension [GO:0048675]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] comp131913_c0_seq1,988,34.2105,0.18396596,0,0,,4.00E-06,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131913_c0_seq6,794,34.5088,0.22172057,0,0,,1.00E-06,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131918_c2_seq1,997,44.2327,1.08795206,11,252,,7.00E-18,Q60847,Collagen alpha-1(XII) chain,Collagen alpha-1(XII) chain,GO:0007155; GO:0005581; GO:0005615; GO:0070062,cell adhesion; collagen; extracellular space; extracellular vesicular exosome,PF01391;PF00041;PF00092;,,,,,,,,,COCA1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] comp131919_c1_seq1,707,40.4526,1.26377242,6,117,,2.00E-09,Q9GPR3,TM2 domain-containing protein DDB_G0277895,TM2 domain-containing protein DDB_G0277895,GO:0016021,integral to membrane,PF05154;,,,,,,,,,TM2D1_DICDI,Dictyostelium discoideum (Slime mold), comp131920_c0_seq1,2082,36.9356,1.00178171,335,10530,,5.00E-30,P55083,Microfibril-associated glycoprotein 4,Microfibril-associated glycoprotein 4,GO:0007155; GO:0030198; GO:0001527,cell adhesion; extracellular matrix organization; microfibril,PF00147;,,,,,,,,,MFAP4_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cellular response to UV-B [GO:0071493]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; regulation of collagen metabolic process [GO:0010712]; UV protection [GO:0009650] comp131923_c0_seq1,1081,34.1351,0.45366915,66,549,,1.00E-09,P16230,Sarcoplasmic reticulum histidine-rich calcium-binding protein,Sarcoplasmic reticulum histidine-rich calcium-binding protein,GO:0033018,sarcoplasmic reticulum lumen,PF10529;,2.00E-37,CHOYP_NEMVEDRAFT_V1G232294.1.1,,,,,,,SRCH_RABIT,Oryctolagus cuniculus (Rabbit), comp131927_c1_seq1,1170,46.0684,0.50056573,107,3,,0,Q96RK4,Bardet-Biedl syndrome 4 protein,Bardet-Biedl syndrome 4 protein,GO:0034464; GO:0030534; GO:0043014; GO:0048487; GO:0048854; GO:0034451; GO:0005814; GO:0051297; GO:0021987; GO:0060170; GO:0060027; GO:0000910; GO:0016358; GO:0034452; GO:0045444; GO:0001947; GO:0021766; GO:0046907; GO:0051457; GO:0032402; GO:0034454; GO:0005932; GO:0003777; GO:0038108; GO:0010629; GO:0003085; GO:0001843; GO:0031513; GO:0035058; GO:0000242; GO:0045494; GO:0051877; GO:0045724; GO:0040018; GO:0060296; GO:0032465; GO:0019216; GO:0046548; GO:0007608; GO:0050893; GO:0007286; GO:0021756; GO:0007601,BBSome; adult behavior; alpha-tubulin binding; beta-tubulin binding; brain morphogenesis; centriolar satellite; centriole; centrosome organization; cerebral cortex development; cilium membrane; convergent extension involved in gastrulation; cytokinesis; dendrite development; dynactin binding; fat cell differentiation; heart looping; hippocampus development; intracellular transport; maintenance of protein location in nucleus; melanosome transport; microtubule anchoring at centrosome; microtubule basal body; microtubule motor activity; negative regulation of appetite by leptin-mediated signaling pathway; negative regulation of gene expression; negative regulation of systemic arterial blood pressure; neural tube closure; nonmotile primary cilium; nonmotile primary cilium assembly; pericentriolar material; photoreceptor cell maintenance; pigment granule aggregation in cell center; positive regulation of cilium assembly; positive regulation of multicellular organism growth; regulation of cilium beat frequency involved in ciliary motility; regulation of cytokinesis; regulation of lipid metabolic process; retinal rod cell development; sensory perception of smell; sensory processing; spermatid development; striatum development; visual perception,PF13414;PF13181;,0,CHOYP_BBS4.1.1,,,,,,,BBS4_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; dendrite development [GO:0016358]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; fat pad development [GO:0060613]; heart looping [GO:0001947]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; maintenance of protein location in nucleus [GO:0051457]; melanosome transport [GO:0032402]; microtubule anchoring at centrosome [GO:0034454]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of systemic arterial blood pressure [GO:0003085]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of cilium assembly [GO:0045724]; positive regulation of multicellular organism growth [GO:0040018]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to organelle [GO:0033365]; protein localization to photoreceptor outer segment [GO:1903546]; protein transport [GO:0015031]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of cytokinesis [GO:0032465]; regulation of lipid metabolic process [GO:0019216]; regulation of nonmotile primary cilium assembly [GO:1902855]; regulation of stress fiber assembly [GO:0051492]; retina homeostasis [GO:0001895]; retinal rod cell development [GO:0046548]; sensory perception of smell [GO:0007608]; sensory processing [GO:0050893]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601] comp131928_c0_seq1,268,40.6716,0.73498291,42,76,,1.00E-14,Q568W0,Selenoprotein W (SelW),Selenoprotein W (SelW),GO:0016209; GO:0045454; GO:0005737; GO:0008430,antioxidant activity; cell redox homeostasis; cytoplasm; selenium binding,PF10262;,,,,,,,,,SELW_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp131930_c0_seq1,230,37.3913,1.13422766,5,52,,1.00E-09,Q61554,Fibrillin-1,Fibrillin-1 [Cleaved into: Asprosin],GO:0005509; GO:0005201; GO:0001527; GO:0035582; GO:0035583,calcium ion binding; extracellular matrix structural constituent; microfibril; sequestering of BMP in extracellular matrix; sequestering of TGFbeta in extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN1_MOUSE,Mus musculus (Mouse),activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] comp131943_c0_seq1,2327,42.4151,1.06823444,240,652,,1.00E-54,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,7.00E-29,CHOYP_LOC100882592.1.1,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp131951_c0_seq1,1048,43.3206,0.58827589,115,33,,4.00E-15,Q22472,Resistance to inhibitors of cholinesterase protein 3,Resistance to inhibitors of cholinesterase protein 3,GO:0005783; GO:0005789; GO:0016021; GO:0043005; GO:0043025; GO:0032224; GO:0034394; GO:0007271,"endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; neuron projection; neuronal cell body; positive regulation of synaptic transmission, cholinergic; protein localization to cell surface; synaptic transmission, cholinergic",PF15361;,,,,,,,,,RIC3_CAEEL,Caenorhabditis elegans,"positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein localization to cell surface [GO:0034394]; synaptic transmission, cholinergic [GO:0007271]" comp131954_c0_seq1,1250,41.76,0.67253086,61095,237703,,2.00E-149,Q26481,60S ribosomal protein L5,60S ribosomal protein L5,GO:0008097; GO:0005840; GO:0003735; GO:0006412,5S rRNA binding; ribosome; structural constituent of ribosome; translation,PF14204;PF17144;,1.00E-155,CHOYP_RL5.2.4,0,ruditapes2_c3334,,,,,RL5_STYCL,Styela clava (Sea squirt),translation [GO:0006412] comp131955_c0_seq1,1255,44.4622,0.42832624,28,143,,3.00E-68,Q58DT4,"Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2)","Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2)",GO:0055129; GO:0034599; GO:0005739; GO:0006561; GO:0004735,L-proline biosynthetic process; cellular response to oxidative stress; mitochondrion; proline biosynthetic process; pyrroline-5-carboxylate reductase activity,PF03807;PF14748;,2.00E-40,CHOYP_contig_007115,5.00E-51,ruditapes_c15383,,,,,P5CR1_BOVIN,Bos taurus (Bovine),cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881] comp131961_c0_seq1,1710,37.4854,0.49980543,0,6,,,,,,,,,1.00E-37,CHOYP_BRAFLDRAFT_79227.1.1,,,,,,,,, comp131961_c0_seq3,1736,37.5,0.50837441,3,17,,4.00E-23,Q2KI52,Hydrolethalus syndrome protein 1 homolog,Hydrolethalus syndrome protein 1 homolog,GO:0005813; GO:0005737; GO:0005634; GO:0005886,centrosome; cytoplasm; nucleus; plasma membrane,PF15311;,1.00E-37,CHOYP_BRAFLDRAFT_79227.1.1,,,,,,,HYLS1_BOVIN,Bos taurus (Bovine), comp131966_c0_seq1,408,42.6471,0.88432964,37,14,,3.00E-32,P58545,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,,,,,,,,,BTBD3_MOUSE,Mus musculus (Mouse),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813] comp131971_c0_seq1,885,37.4011,0.52102389,33,499,,1.00E-26,A6QPH1,Partner of Y14 and mago (Protein wibg homolog),Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog),GO:0005737; GO:0035145; GO:0000184; GO:0005730; GO:0005654; GO:0045727; GO:0043022,"cytoplasm; exon-exon junction complex; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleolus; nucleoplasm; positive regulation of translation; ribosome binding",PF09282;,2.00E-18,CHOYP_LOC100371258.1.1,,,,,,,WIBG_BOVIN,Bos taurus (Bovine),"exon-exon junction complex disassembly [GO:1903259]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]" comp131973_c0_seq10,450,40,0.5021054,13,58,,8.00E-16,Q96NL8,Protein C8orf37,Protein C8orf37,GO:0005737,cytoplasm,PF14996;,,,,,,,,,CH037_HUMAN,Homo sapiens (Human), comp131973_c0_seq8,524,37.5954,0.43424476,0,0,,3.00E-16,Q3UJP5,Protein C8orf37 homolog,Protein C8orf37 homolog,GO:0005737,cytoplasm,PF14996;,,,,,,,,,CH037_MOUSE,Mus musculus (Mouse), comp131975_c0_seq1,1734,39.9654,0.33496469,63,178,,4.00E-27,P23708,Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA),Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA),GO:0016602; GO:0003677; GO:0005654; GO:2000648; GO:0045944; GO:2000036; GO:0003700; GO:0006351,"CCAAT-binding factor complex; DNA binding; nucleoplasm; positive regulation of stem cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of stem cell maintenance; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02045;,7.00E-40,CHOYP_NFYA.2.2,,,,,,,NFYA_MOUSE,Mus musculus (Mouse),"positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]" comp131976_c0_seq6,1016,36.3189,0.57117998,1,8,,2.00E-11,Q94521,Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),GO:0004059; GO:0004060; GO:0005737; GO:0048066; GO:0042420; GO:0030187; GO:0046334; GO:0045187; GO:0042429; GO:0030431,"aralkylamine N-acetyltransferase activity; arylamine N-acetyltransferase activity; cytoplasm; developmental pigmentation; dopamine catabolic process; melatonin biosynthetic process; octopamine catabolic process; regulation of circadian sleep/wake cycle, sleep; serotonin catabolic process; sleep",PF00583;,,,,,,,,,DNAT_DROME,Drosophila melanogaster (Fruit fly),"catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]" comp131976_c1_seq1,437,29.7483,1.26316451,22,70,,1.00E-09,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp131982_c0_seq1,2179,45.4796,0.3842434,92,93,,7.00E-163,Q9UHJ3,Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1),Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1),GO:0030154; GO:0016568; GO:0042393; GO:0048635; GO:0045892; GO:0005634; GO:0007283; GO:0003714; GO:0006351,"cell differentiation; chromatin modification; histone binding; negative regulation of muscle organ development; negative regulation of transcription, DNA-dependent; nucleus; spermatogenesis; transcription corepressor activity; transcription, DNA-dependent",PF12140;PF02820;PF00536;,4.00E-82,CHOYP_BRAFLDRAFT_226942.1.1,,,,,,,SMBT1_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; chromatin modification [GO:0016568]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription, DNA-templated [GO:0045892]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp131982_c1_seq1,680,42.2059,0.43034314,27,14,,3.00E-12,Q80VG1,Sex comb on midleg-like protein 4,Sex comb on midleg-like protein 4,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12140;PF00536;,,,,,,,,,SCML4_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp131983_c1_seq1,1229,36.8592,0.91935545,25,244,,5.00E-50,Q9CX98,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_MOUSE,Mus musculus (Mouse), comp131985_c0_seq2,769,46.1638,0.46163148,0,6,,1.00E-109,P53611,Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta),Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta),GO:0004663; GO:0006464; GO:0046872; GO:0018344; GO:0007601,Rab geranylgeranyltransferase activity; cellular protein modification process; metal ion binding; protein geranylgeranylation; visual perception,PF00432;,,,,,,,,,PGTB2_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; protein geranylgeranylation [GO:0018344]; regulation of apoptotic process [GO:0042981]; visual perception [GO:0007601] comp131985_c0_seq4,1124,41.726,0.40760902,39,138,,1.00E-110,P53611,Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta),Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta),GO:0004663; GO:0006464; GO:0046872; GO:0018344; GO:0007601,Rab geranylgeranyltransferase activity; cellular protein modification process; metal ion binding; protein geranylgeranylation; visual perception,PF00432;,1.00E-91,CHOYP_PGTB2.1.1,,,,,,,PGTB2_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; protein geranylgeranylation [GO:0018344]; regulation of apoptotic process [GO:0042981]; visual perception [GO:0007601] comp131993_c0_seq1,1880,43.0319,0.57487791,82,118,,9.00E-46,O08876,Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (Zinc finger transcription factor homolog CPG20),Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (Zinc finger transcription factor homolog CPG20),GO:0003677; GO:0030282; GO:1901653; GO:0046872; GO:0005634; GO:0045672; GO:0006355; GO:0035019; GO:0006351,"DNA binding; bone mineralization; cellular response to peptide; metal ion binding; nucleus; positive regulation of osteoclast differentiation; regulation of transcription, DNA-dependent; somatic stem cell maintenance; transcription, DNA-dependent",,1.00E-24,CHOYP_KLF5.1.1,,,,,,,KLF10_RAT,Rattus norvegicus (Rat),"bone mineralization [GO:0030282]; cellular response to peptide [GO:1901653]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of osteoclast differentiation [GO:0045672]; regulation of circadian rhythm [GO:0042752]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]" comp131996_c0_seq1,1954,42.3234,0.56526049,51,489,,3.00E-94,P63240,Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1),Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1),GO:0006508; GO:0004252; GO:0030133,proteolysis; serine-type endopeptidase activity; transport vesicle,PF01483;PF00082;PF12177;PF16470;,8.00E-21,CHOYP_LOC100202203.1.1,,,,,,,NEC1_MUSCO,Mus cookii (Cook's mouse), comp132007_c0_seq1,397,46.3476,0.80894822,0,22,,2.00E-29,P30531,Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1),Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1),GO:0030424; GO:0009986; GO:0051939; GO:0005332; GO:0016021; GO:0005887; GO:0007612; GO:0032229; GO:0007269; GO:0005328; GO:0005886; GO:0014054; GO:0051260; GO:0051592; GO:0042220; GO:0032355; GO:0010288; GO:0014074; GO:0009744; GO:0009636; GO:0055085,"axon; cell surface; gamma-aminobutyric acid import; gamma-aminobutyric acid:sodium symporter activity; integral to membrane; integral to plasma membrane; learning; negative regulation of synaptic transmission, GABAergic; neurotransmitter secretion; neurotransmitter:sodium symporter activity; plasma membrane; positive regulation of gamma-aminobutyric acid secretion; protein homooligomerization; response to calcium ion; response to cocaine; response to estradiol stimulus; response to lead ion; response to purine-containing compound; response to sucrose stimulus; response to toxic substance; transmembrane transport",PF00209;,4.00E-23,CHOYP_SC6A9.1.6,,,,,,,SC6A1_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; learning [GO:0007612]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neurotransmitter transport [GO:0006836]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; protein homooligomerization [GO:0051260]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to lead ion [GO:0010288]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; transport [GO:0006810]" comp132007_c0_seq2,376,43.3511,0.91811913,0,0,,4.00E-09,Q2A865,Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1),Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1),GO:0005887; GO:0005328; GO:0015175; GO:0007584,integral to plasma membrane; neurotransmitter:sodium symporter activity; neutral amino acid transmembrane transporter activity; response to nutrient,PF00209;,,,,,,,,,S6A19_RAT,Rattus norvegicus (Rat),response to nutrient [GO:0007584] comp132007_c1_seq1,639,42.5665,1.07973054,0,0,,3.00E-12,B4L7U0,Sodium-dependent nutrient amino acid transporter 1,Sodium-dependent nutrient amino acid transporter 1,GO:0042943; GO:0005887; GO:0005328; GO:0015175; GO:0005283,D-amino acid transmembrane transporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity; neutral amino acid transmembrane transporter activity; sodium:amino acid symporter activity,PF00209;,,,,,,,,,NAAT1_DROMO,Drosophila mojavensis (Fruit fly),D-amino acid transport [GO:0042940]; neutral amino acid transport [GO:0015804]; sodium ion transport [GO:0006814] comp132010_c0_seq1,1230,40.7317,0.57636707,308,1428,,1.00E-140,A4FUD1,GPN-loop GTPase 1 (XPA-binding protein 1),GPN-loop GTPase 1 (EC 3.6.5.-) (XPA-binding protein 1),GO:0005525; GO:0005737; GO:0017111,GTP binding; cytoplasm; nucleoside-triphosphatase activity,PF03029;,7.00E-127,CHOYP_LOC101071050.1.1,4.00E-77,ruditapes_c10612,,,,,GPN1_BOVIN,Bos taurus (Bovine), comp132012_c0_seq2,340,40.2941,0.81191179,0,0,,9.00E-19,Q86YJ7,Ankyrin repeat domain-containing protein 13B,Ankyrin repeat domain-containing protein 13B,GO:0005769; GO:0005770; GO:0005886,early endosome; late endosome; plasma membrane,PF12796;PF11904;,,,,,,,,,AN13B_HUMAN,Homo sapiens (Human), comp132012_c0_seq4,2076,43.1599,0.58490874,0,0,,0,Q86YJ7,Ankyrin repeat domain-containing protein 13B,Ankyrin repeat domain-containing protein 13B,GO:0005769; GO:0005770; GO:0005886,early endosome; late endosome; plasma membrane,PF12796;PF11904;,,,,,,,,,AN13B_HUMAN,Homo sapiens (Human), comp132012_c0_seq5,1944,43.3642,0.53038839,0,0,,0,Q6PD24,Ankyrin repeat domain-containing protein 13D,Ankyrin repeat domain-containing protein 13D,GO:0005770; GO:0005886,late endosome; plasma membrane,PF12796;PF11904;,7.00E-174,CHOYP_AN13B.1.1,,,,,,,AN13D_MOUSE,Mus musculus (Mouse), comp132014_c0_seq1,1610,38.5714,0.85382691,107,267,,4.00E-16,Q6DG99,BTB/POZ domain-containing protein KCTD6,BTB/POZ domain-containing protein KCTD6,GO:0051260,protein homooligomerization,PF02214;,,,,,,,,,KCTD6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein homooligomerization [GO:0051260] comp132016_c0_seq1,2503,38.9932,0.69866083,42080,176040,,5.00E-32,P07909,Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),GO:0036099; GO:0048027; GO:0033119; GO:0000166; GO:0005634; GO:0048477; GO:0005703; GO:0045727; GO:0000381; GO:0030529; GO:0043565,"female germ-line stem cell maintenance; mRNA 5'-UTR binding; negative regulation of RNA splicing; nucleotide binding; nucleus; oogenesis; polytene chromosome puff; positive regulation of translation; regulation of alternative mRNA splicing, via spliceosome; ribonucleoprotein complex; sequence-specific DNA binding",PF00076;,,,,,,,,,ROA1_DROME,Drosophila melanogaster (Fruit fly),"compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]" comp132017_c0_seq1,759,46.2451,0.55112496,29,15,,1.00E-101,O94972,E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37),E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37),GO:0016235; GO:0070842; GO:0005829; GO:0032088; GO:0046600; GO:0048471; GO:0005777; GO:0051865; GO:0042803; GO:0004842; GO:0008270,aggresome; aggresome assembly; cytosol; negative regulation of NF-kappaB transcription factor activity; negative regulation of centriole replication; perinuclear region of cytoplasm; peroxisome; protein autoubiquitination; protein homodimerization activity; ubiquitin-protein ligase activity; zinc ion binding,PF00917;PF00643;,6.00E-94,CHOYP_HS90A.3.3,,,,,,,TRI37_HUMAN,Homo sapiens (Human),"aggresome assembly [GO:0070842]; histone H2A-K119 monoubiquitination [GO:0036353]; histone H2A monoubiquitination [GO:0035518]; negative regulation of centriole replication [GO:0046600]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; transcription, DNA-templated [GO:0006351]" comp132020_c0_seq1,1019,43.2777,0.34459493,136,14,,2.00E-48,P11862,Growth arrest-specific protein 2 (GAS-2),Growth arrest-specific protein 2 (GAS-2),GO:0006915; GO:0007050; GO:0005737; GO:0005856; GO:0016020; GO:0008360,apoptotic process; cell cycle arrest; cytoplasm; cytoskeleton; membrane; regulation of cell shape,PF00307;PF02187;,1.00E-33,CHOYP_LOC100485604.1.1,,,,,,,GAS2_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell cycle arrest [GO:0007050]; regulation of cell shape [GO:0008360] comp132023_c0_seq6,1069,43.3115,0.74853535,2,10,,4.00E-29,Q06S87,5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein),5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein),GO:0016811; GO:0033971; GO:0005777; GO:0006144; GO:0006810; GO:0019628,"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; hydroxyisourate hydrolase activity; peroxisome; purine nucleobase metabolic process; transport; urate catabolic process",PF00576;,,,,,,,,,HIUH_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] comp132023_c0_seq7,852,36.9718,0.51768157,5,38,,1.00E-29,Q06S87,5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein),5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein),GO:0016811; GO:0033971; GO:0005777; GO:0006144; GO:0006810; GO:0019628,"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; hydroxyisourate hydrolase activity; peroxisome; purine nucleobase metabolic process; transport; urate catabolic process",PF00576;,2.00E-18,CHOYP_LOC100313757.1.1,7.00E-15,ruditapes2_c2768,,,,,HIUH_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] comp132025_c1_seq1,1834,38.4406,1.18626298,22,227,,4.00E-27,P55040,GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR),GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR),GO:0019003; GO:0005525; GO:0003924; GO:0007166; GO:0051276; GO:0006955; GO:0009898; GO:0000287; GO:0030496; GO:0007067; GO:0072686; GO:0005634; GO:0007264; GO:0051233,GDP binding; GTP binding; GTPase activity; cell surface receptor signaling pathway; chromosome organization; immune response; internal side of plasma membrane; magnesium ion binding; midbody; mitosis; mitotic spindle; nucleus; small GTPase mediated signal transduction; spindle midzone,PF00071;,,,,,,,,,GEM_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; chromosome organization [GO:0051276]; immune response [GO:0006955]; metaphase plate congression [GO:0051310]; mitotic nuclear division [GO:0007067]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] comp132025_c1_seq2,1110,36.1261,1.10552854,0,5,,3.00E-07,Q9H0T7,Ras-related protein Rab-17,Ras-related protein Rab-17,GO:0019003; GO:0005525; GO:0016324; GO:0016323; GO:0030425; GO:0032456; GO:0046847; GO:0002415; GO:0042470; GO:0032402; GO:0043025; GO:0015031; GO:0055038; GO:0050773; GO:0051489; GO:0051963; GO:0007264,GDP binding; GTP binding; apical plasma membrane; basolateral plasma membrane; dendrite; endocytic recycling; filopodium assembly; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; melanosome; melanosome transport; neuronal cell body; protein transport; recycling endosome membrane; regulation of dendrite development; regulation of filopodium assembly; regulation of synapse assembly; small GTPase mediated signal transduction,PF00071;,8.00E-12,CHOYP_AGAP_AGAP007681.1.1,,,,,,,RAB17_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; endocytic recycling [GO:0032456]; establishment of melanosome localization [GO:0032401]; filopodium assembly [GO:0046847]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; melanosome transport [GO:0032402]; protein transport [GO:0015031]; regulation of dendrite development [GO:0050773]; regulation of endocytosis [GO:0030100]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; small GTPase mediated signal transduction [GO:0007264]; transcytosis [GO:0045056] comp132028_c5_seq1,1138,38.7522,1.21833311,33,297,,5.00E-08,Q16950,5-hydroxytryptamine receptor 1 (5-HTB1) (Serotonin receptor 1),5-hydroxytryptamine receptor 1 (5-HTB1) (Serotonin receptor 1),GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00001;,,,,,,,,,5HTB1_APLCA,Aplysia californica (California sea hare), comp132031_c0_seq1,1406,44.8791,0.38803901,36,27,,3.00E-118,Q8IYD8,Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0071821; GO:0043240; GO:0003682; GO:0004518; GO:0090305; GO:0031297; GO:0000712,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; FANCM-MHF complex; Fanconi anaemia nuclear complex; chromatin binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; replication fork processing; resolution of meiotic recombination intermediates,PF02732;PF16783;PF00271;PF04851;,,,,,,,,,FANCM_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp132031_c0_seq3,941,44.102,0.53828632,0,0,,8.00E-61,Q0CWI2,ATP-dependent DNA helicase mph1 (EC 3.6.4.12),ATP-dependent DNA helicase mph1 (EC 3.6.4.12) (FANCM-like protein 1),GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0005634,ATP binding; DNA binding; DNA repair; helicase activity; nucleus,PF00271;PF04851;,2.00E-87,CHOYP_BRAFLDRAFT_118736.1.1,5.00E-24,ruditapes_c15344,,,,,MPH1_ASPTN,Aspergillus terreus (strain NIH 2624 / FGSC A1156),DNA repair [GO:0006281] comp13203_c0_seq1,316,45.8861,0.30225322,9,0,,5.00E-14,P85171,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,,,,,,,,,MDGA1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp132041_c0_seq2,2875,43.513,0.51491394,147,10,,1.00E-72,Q63132,Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase),Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase),GO:0005524; GO:0016049; GO:0008283; GO:0002066; GO:0016021; GO:0010629; GO:0005886; GO:0004713; GO:0070372; GO:0032006; GO:0010966; GO:0007283; GO:0004714,ATP binding; cell growth; cell proliferation; columnar/cuboidal epithelial cell development; integral to membrane; negative regulation of gene expression; plasma membrane; protein tyrosine kinase activity; regulation of ERK1 and ERK2 cascade; regulation of TOR signaling cascade; regulation of phosphate transport; spermatogenesis; transmembrane receptor protein tyrosine kinase activity,PF00041;PF07714;,,,,,,,,,ROS1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; columnar/cuboidal epithelial cell development [GO:0002066]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphate transport [GO:0010966]; regulation of TOR signaling [GO:0032006]; signal transduction by protein phosphorylation [GO:0023014]; spermatogenesis [GO:0007283] comp132041_c1_seq1,1207,46.8103,0.46941468,62,0,,6.00E-18,P20806,Protein sevenless (EC 2.7.10.1),Protein sevenless (EC 2.7.10.1),GO:0005524; GO:0016021; GO:0018108; GO:0005886; GO:0004714; GO:0007169; GO:0007601,ATP binding; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway; visual perception,PF00041;PF07714;,,,,,,,,,7LESS_DROVI,Drosophila virilis (Fruit fly),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; visual perception [GO:0007601] comp132043_c0_seq1,1193,45.767,0.50698589,86,69,,1.00E-172,P79987,Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1),Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1),GO:0003682; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07569;PF09453;PF00400;,1.00E-148,CHOYP_HIRA.1.1,,,,,,,HIRA_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132043_c1_seq1,1026,43.3723,0.4812171,71,51,,2.00E-18,Q8QFR2,Protein HIRA,Protein HIRA,GO:0003682; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07569;PF09453;PF00400;,,,,,,,,,HIRA_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132045_c0_seq1,1618,36.712,0.63937859,205,274,,1.00E-40,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,1.00E-12,CHOYP_HSPA12A.2.27,1.00E-78,ruditapes_c1110,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp132046_c0_seq1,849,43.3451,0.35253041,25,78,,3.00E-47,Q27974,Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6),Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6),GO:0035335; GO:0004725,peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00226;PF10409;,4.00E-40,CHOYP_GAK.1.1,,,,,,,AUXI_BOVIN,Bos taurus (Bovine),receptor-mediated endocytosis [GO:0006898] comp132047_c1_seq1,320,40,0.31625925,5,3,,4.00E-07,Q25637,Period circadian protein,Period circadian protein,GO:0005634; GO:0006355; GO:0048511; GO:0004871,"nucleus; regulation of transcription, DNA-dependent; rhythmic process; signal transducer activity",PF00989;,,,,,,,,,PER_PERAM,Periplaneta americana (American cockroach) (Blatta americana),"regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]" comp132047_c3_seq1,1928,45.0726,0.62364337,24,53,,3.00E-38,Q25637,Period circadian protein,Period circadian protein,GO:0005634; GO:0006355; GO:0048511; GO:0004871,"nucleus; regulation of transcription, DNA-dependent; rhythmic process; signal transducer activity",PF00989;,,,,,,,,,PER_PERAM,Periplaneta americana (American cockroach) (Blatta americana),"regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]" comp132057_c0_seq1,1308,39.9847,0.48047305,0,15,,7.00E-81,Q09305,Protein AAR2 homolog (AAR2 splicing factor homolog),Protein AAR2 homolog (AAR2 splicing factor homolog),,,PF05282;,,,,,,,,,AAR2_CAEEL,Caenorhabditis elegans,spliceosomal tri-snRNP complex assembly [GO:0000244] comp132057_c0_seq3,1709,37.4488,0.57022941,4,15,,8.00E-121,Q9D2V5,Protein AAR2 homolog (AAR2 splicing factor homolog),Protein AAR2 homolog (AAR2 splicing factor homolog),,,PF05282;,3.00E-39,CHOYP_BRAFLDRAFT_260828.1.1,,,,,,,AAR2_MOUSE,Mus musculus (Mouse),spliceosomal tri-snRNP complex assembly [GO:0000244] comp132060_c1_seq1,1588,42.0655,0.4281828,173,415,,1.00E-08,Q90577,Sarcalumenin,Sarcalumenin,GO:0005525; GO:0006184; GO:0003924; GO:0033018,GTP binding; GTP catabolic process; GTPase activity; sarcoplasmic reticulum lumen,PF00350;PF16880;,0,CHOYP_BRAFLDRAFT_282105.1.2,,,,,,,SRCA_CHICK,Gallus gallus (Chicken), comp132067_c1_seq1,1104,37.5906,0.46314014,41,256,,7.00E-113,Q6PGW3,UPF0668 protein C10orf76 homolog,UPF0668 protein C10orf76 homolog,GO:0016021,integral to membrane,PF08427;,2.00E-115,CHOYP_ISCW_ISCW018656.1.1,,,,,,,CJ076_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp132067_c2_seq1,1148,43.4669,0.46144613,3,36,,1.00E-115,Q6PD19,UPF0668 protein C10orf76 homolog,UPF0668 protein C10orf76 homolog,GO:0016021,integral to membrane,PF08427;,,,,,,,,,CJ076_MOUSE,Mus musculus (Mouse), comp132067_c2_seq3,492,37.8049,0.40825911,0,0,,,,,,,,,3.00E-45,CHOYP_ISCW_ISCW018656.1.1,,,,,,,,, comp132070_c2_seq2,810,42.716,0.52255234,7,21,,1.00E-24,Q6NXK5,RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1),RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1),GO:0003723; GO:0005634; GO:0035335; GO:0004725; GO:0008138,RNA binding; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,,,,,,,,,DUS11_MOUSE,Mus musculus (Mouse),polynucleotide 5' dephosphorylation [GO:0098507]; RNA metabolic process [GO:0016070] comp132075_c0_seq1,1147,37.7507,0.59045949,64883,210189,,,,,,,,,3.00E-24,CHOYP_FEM1C-Z.1.1,2.00E-24,ruditapes_lrc37813,,,,,,, comp132075_c0_seq2,1173,38.1927,0.56290122,58726,246799,,,,,,,,,3.00E-24,CHOYP_CRNS1.1.1,2.00E-30,ruditapes_lrc32296,,,,,,, comp132076_c0_seq2,1621,42.9365,0.45796097,0,0,,7.00E-48,Q75J93,Circularly permutated Ras protein 1 (DdiCPRas1),Circularly permutated Ras protein 1 (DdiCPRas1),GO:0030127; GO:0006888; GO:0005525; GO:0003924; GO:0006886; GO:0007264; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; GTP binding; GTPase activity; intracellular protein transport; small GTPase mediated signal transduction; zinc ion binding,PF00071;,,,,,,,,,CPAS1_DICDI,Dictyostelium discoideum (Slime mold),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264] comp132076_c0_seq5,2019,43.6355,0.51831432,0,0,,4.00E-47,Q75J93,Circularly permutated Ras protein 1 (DdiCPRas1),Circularly permutated Ras protein 1 (DdiCPRas1),GO:0030127; GO:0006888; GO:0005525; GO:0003924; GO:0006886; GO:0007264; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; GTP binding; GTPase activity; intracellular protein transport; small GTPase mediated signal transduction; zinc ion binding,PF00071;,,,,,,,,,CPAS1_DICDI,Dictyostelium discoideum (Slime mold),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264] comp132077_c0_seq1,1726,39.7451,0.40082496,197,32,,,,,,,,,2.00E-52,CHOYP_TVAG_193760.1.4,2.00E-57,ruditapes_c18713,,,,,,, comp132079_c1_seq1,906,35.6512,0.90560786,12,1915,,3.00E-55,Q22799,"Dynein light chain 1, cytoplasmic","Dynein light chain 1, cytoplasmic",GO:0005737; GO:0030286; GO:0005874; GO:0007017; GO:0003774,cytoplasm; dynein complex; microtubule; microtubule-based process; motor activity,PF01221;,,,6.00E-80,ruditapes2_lrc5037,,,,,DYL1_CAEEL,Caenorhabditis elegans,microtubule-based process [GO:0007017] comp132079_c1_seq3,606,39.604,0.9338487,276,1563,,,,,,,,,,,9.00E-101,ruditapes2_c439,,,,,,, comp132079_c1_seq4,823,36.5735,0.94712784,19,973,,2.00E-57,Q24117,"Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)","Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)",GO:0042623; GO:0051017; GO:0006914; GO:0005814; GO:0008407; GO:0030286; GO:0000132; GO:0007476; GO:0005874; GO:0034454; GO:0007018; GO:0003774; GO:0022008; GO:0048477; GO:0042803; GO:0035071; GO:0007291; GO:0007290,"ATPase activity, coupled; actin filament bundle assembly; autophagy; centriole; chaeta morphogenesis; dynein complex; establishment of mitotic spindle orientation; imaginal disc-derived wing morphogenesis; microtubule; microtubule anchoring at centrosome; microtubule-based movement; motor activity; neurogenesis; oogenesis; protein homodimerization activity; salivary gland cell autophagic cell death; sperm individualization; spermatid nucleus elongation",PF01221;,,,3.00E-71,ruditapes_lrc23687,,,,,DYL1_DROME,Drosophila melanogaster (Fruit fly),actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of pain [GO:0019233]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220] comp132079_c1_seq5,689,37.4456,0.87712049,1263,5075,,2.00E-28,Q6BZF8,"Dynein light chain 1, cytoplasmic","Dynein light chain 1, cytoplasmic",GO:0005737; GO:0030286; GO:0005874; GO:0007017; GO:0003774; GO:0006810,cytoplasm; dynein complex; microtubule; microtubule-based process; motor activity; transport,PF01221;,,,2.00E-65,ruditapes2_c918,,,,,DYL1_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),"actin filament-based process [GO:0030029]; establishment of mitotic spindle localization [GO:0040001]; metabolic process [GO:0008152]; nuclear migration along microtubule [GO:0030473]; nuclear pore complex assembly [GO:0051292]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]" comp132079_c1_seq6,762,37.5328,0.97088211,4,14,,,,,,,,,,,5.00E-67,ruditapes_c6356,,,,,,, comp132079_c1_seq8,587,39.1823,0.93432475,41,1349,,9.00E-57,Q22799,"Dynein light chain 1, cytoplasmic","Dynein light chain 1, cytoplasmic",GO:0005737; GO:0030286; GO:0005874; GO:0007017; GO:0003774,cytoplasm; dynein complex; microtubule; microtubule-based process; motor activity,PF01221;,3.00E-65,CHOYP_DYL2.3.3,3.00E-56,ruditapes2_lrc5786,,,,,DYL1_CAEEL,Caenorhabditis elegans,microtubule-based process [GO:0007017] comp132079_c1_seq9,504,41.0714,0.99019998,1,30,,5.00E-59,Q24117,"Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)","Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)",GO:0042623; GO:0051017; GO:0006914; GO:0005814; GO:0008407; GO:0030286; GO:0000132; GO:0007476; GO:0005874; GO:0034454; GO:0007018; GO:0003774; GO:0022008; GO:0048477; GO:0042803; GO:0035071; GO:0007291; GO:0007290,"ATPase activity, coupled; actin filament bundle assembly; autophagy; centriole; chaeta morphogenesis; dynein complex; establishment of mitotic spindle orientation; imaginal disc-derived wing morphogenesis; microtubule; microtubule anchoring at centrosome; microtubule-based movement; motor activity; neurogenesis; oogenesis; protein homodimerization activity; salivary gland cell autophagic cell death; sperm individualization; spermatid nucleus elongation",PF01221;,1.00E-74,CHOYP_DYL2.2.3,5.00E-71,ruditapes_c2562,,,,,DYL1_DROME,Drosophila melanogaster (Fruit fly),actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of pain [GO:0019233]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220] comp132086_c1_seq1,1581,45.5408,0.63735489,14,0,,2.00E-111,Q7Z3E5,LisH domain-containing protein ARMC9 (Melanoma/melanocyte-specific tumor antigen KU-MEL-1) (NS21),LisH domain-containing protein ARMC9 (Melanoma/melanocyte-specific tumor antigen KU-MEL-1) (NS21),,,,,,,,,,,,ARMC9_HUMAN,Homo sapiens (Human), comp132086_c1_seq2,1824,44.1886,0.62005825,20,0,,6.00E-108,Q9D2I5,LisH domain-containing protein ARMC9,LisH domain-containing protein ARMC9,,,,8.00E-141,CHOYP_ARMC9.1.1,,,,,,,ARMC9_MOUSE,Mus musculus (Mouse), comp132089_c0_seq4,296,38.5135,0.27731409,0,0,,,,,,,,,4.00E-27,CHOYP_LOC101236784.1.1,,,,,,,,, comp132093_c0_seq1,330,43.0303,0.42436287,1,52,,2.00E-17,Q9M8K7,Dual specificity protein phosphatase 1B (AtDsPTP1B) (EC 3.1.3.16) (EC 3.1.3.48) (MAPK phosphatase 2) (AtMKP2),Dual specificity protein phosphatase 1B (AtDsPTP1B) (EC 3.1.3.16) (EC 3.1.3.48) (MAPK phosphatase 2) (AtMKP2),GO:0033549; GO:0034599; GO:0005737; GO:0007243; GO:0034053; GO:0034051; GO:0005634; GO:0035335; GO:0005886; GO:0004725; GO:0008138; GO:0010193,MAP kinase phosphatase activity; cellular response to oxidative stress; cytoplasm; intracellular protein kinase cascade; modulation by symbiont of host defense-related programmed cell death; negative regulation of plant-type hypersensitive response; nucleus; peptidyl-tyrosine dephosphorylation; plasma membrane; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; response to ozone,PF00782;,,,,,,,,,DUS1B_ARATH,Arabidopsis thaliana (Mouse-ear cress),cellular response to oxidative stress [GO:0034599]; intracellular signal transduction [GO:0035556]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of plant-type hypersensitive response [GO:0034051]; response to oxidative stress [GO:0006979]; response to ozone [GO:0010193] comp132093_c1_seq1,1160,43.4483,0.27817732,59,317,,6.00E-45,Q9D0T2,Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1),Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1),GO:0005737; GO:0046872; GO:0005634; GO:0035335; GO:0033133; GO:0004725; GO:0008138,cytoplasm; metal ion binding; nucleus; peptidyl-tyrosine dephosphorylation; positive regulation of glucokinase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,2.00E-19,CHOYP_LOC100678616.1.1,,,,,,,DUS12_MOUSE,Mus musculus (Mouse),positive regulation of glucokinase activity [GO:0033133] comp132096_c0_seq1,382,44.5026,0.8835124,30,101,,2.00E-09,O15164,Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),GO:0055074; GO:0071391; GO:0003682; GO:0005829; GO:0034056; GO:0070577; GO:0008285; GO:0045892; GO:0005719; GO:0005634; GO:0005726; GO:0045893; GO:0046777; GO:0030163; GO:0004672; GO:0005102; GO:0042981; GO:0031647; GO:0070562; GO:0043565; GO:0003713; GO:0006366; GO:0004842; GO:0008270,"calcium ion homeostasis; cellular response to estrogen stimulus; chromatin binding; cytosol; estrogen response element binding; histone acetyl-lysine binding; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nuclear euchromatin; nucleus; perichromatin fibrils; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein catabolic process; protein kinase activity; receptor binding; regulation of apoptotic process; regulation of protein stability; regulation of vitamin D receptor signaling pathway; sequence-specific DNA binding; transcription coactivator activity; transcription from RNA polymerase II promoter; ubiquitin-protein ligase activity; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TIF1A_HUMAN,Homo sapiens (Human),"calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]" comp132096_c0_seq2,366,41.2568,1.3522577,40,141,,4.00E-11,Q6E2N3,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TRI33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp132097_c0_seq3,237,40.0844,0.21976384,8,28,,1.00E-07,Q9D494,Uncharacterized protein C15orf43 homolog,Telomere repeats-binding bouquet formation protein 2,,,PF15101;,,,,,,,,,CO043_MOUSE,Mus musculus (Mouse),meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129] comp132099_c0_seq11,1417,46.8596,0.62505658,0,0,,8.00E-15,Q0IIC4,Zinc finger matrin-type protein 3,Zinc finger matrin-type protein 3,GO:0003723; GO:0006915; GO:0005730; GO:0015031; GO:0040008; GO:0006974; GO:0008270,RNA binding; apoptotic process; nucleolus; protein transport; regulation of growth; response to DNA damage stimulus; zinc ion binding,PF12171;,,,,,,,,,ZMAT3_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein transport [GO:0015031]; regulation of growth [GO:0040008] comp132099_c0_seq13,1879,43.7467,0.70228317,0,0,,3.00E-14,Q9HA38,Zinc finger matrin-type protein 3 (Zinc finger protein WIG-1) (p53-activated gene 608 protein),Zinc finger matrin-type protein 3 (Zinc finger protein WIG-1) (p53-activated gene 608 protein),GO:0003723; GO:0006915; GO:0005730; GO:0015031; GO:0040008; GO:0006974; GO:0008270,RNA binding; apoptotic process; nucleolus; protein transport; regulation of growth; response to DNA damage stimulus; zinc ion binding,PF12171;,,,,,,,,,ZMAT3_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of apoptotic process [GO:0043065]; protein transport [GO:0015031]; regulation of growth [GO:0040008] comp132099_c0_seq3,2631,42.4933,0.656032,0,0,,2.00E-14,Q0IIC4,Zinc finger matrin-type protein 3,Zinc finger matrin-type protein 3,GO:0003723; GO:0006915; GO:0005730; GO:0015031; GO:0040008; GO:0006974; GO:0008270,RNA binding; apoptotic process; nucleolus; protein transport; regulation of growth; response to DNA damage stimulus; zinc ion binding,PF12171;,,,,,,,,,ZMAT3_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein transport [GO:0015031]; regulation of growth [GO:0040008] comp132099_c0_seq4,2356,42.8693,0.67822127,0,0,,3.00E-07,Q0VD35,Zinc finger matrin-type protein 4,Zinc finger matrin-type protein 4,GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,PF12171;,,,,,,,,,ZMAT4_BOVIN,Bos taurus (Bovine),intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332] comp132099_c0_seq5,1604,44.5137,0.7415355,0,0,,2.00E-08,Q28EG9,Zinc finger matrin-type protein 1,Zinc finger matrin-type protein 1,GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,,,,,,,,,,ZMAT1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332] comp132104_c0_seq1,1136,43.75,0.44737394,0,0,,,,,,,,,4.00E-66,CHOYP_BRAFLDRAFT_123642.2.2,,,,,,,,, comp132104_c0_seq2,1837,40.0109,0.49560878,21,64,,1.00E-42,O80925,ADP-ribosylation factor GTPase-activating protein AGD7 (ARF GAP AGD7) (Protein ARF-GAP DOMAIN 7) (AtAGD7) (Protein PDE1 SUPPRESSOR 1),ADP-ribosylation factor GTPase-activating protein AGD7 (ARF GAP AGD7) (Protein ARF-GAP DOMAIN 7) (AtAGD7) (Protein PDE1 SUPPRESSOR 1),GO:0008060; GO:0005794; GO:0005829; GO:0005634; GO:0043547; GO:0032312; GO:0016192; GO:0008270,ARF GTPase activator activity; Golgi apparatus; cytosol; nucleus; positive regulation of GTPase activity; regulation of ARF GTPase activity; vesicle-mediated transport; zinc ion binding,PF01412;,,,,,,,,,AGD7_ARATH,Arabidopsis thaliana (Mouse-ear cress),vesicle-mediated transport [GO:0016192] comp132104_c0_seq3,1331,43.2757,0.46480585,0,0,,2.00E-94,Q8N6T3,ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein),ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein),GO:0008060; GO:0048205; GO:0005096; GO:0030660; GO:0006987; GO:0044267; GO:0005829; GO:0005783; GO:0031965; GO:0005886; GO:0015031; GO:0032312; GO:0006890; GO:0045202; GO:0008270,"ARF GTPase activator activity; COPI coating of Golgi vesicle; GTPase activator activity; Golgi-associated vesicle membrane; activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; cytosol; endoplasmic reticulum; nuclear membrane; plasma membrane; protein transport; regulation of ARF GTPase activity; retrograde vesicle-mediated transport, Golgi to ER; synapse; zinc ion binding",PF01412;,2.00E-59,CHOYP_BRAFLDRAFT_123642.1.2,,,,,,,ARFG1_HUMAN,Homo sapiens (Human),"ER to Golgi vesicle-mediated transport [GO:0006888]; IRE1-mediated unfolded protein response [GO:0036498]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp132105_c0_seq1,2095,42.2912,0.58040858,52,1916,,2.00E-72,Q6AY09,"Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]","Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]",GO:0003723; GO:0015629; GO:0005737; GO:0005654; GO:0000166; GO:0030529,RNA binding; actin cytoskeleton; cytoplasm; nucleoplasm; nucleotide binding; ribonucleoprotein complex,PF00076;PF08080;,5.00E-87,CHOYP_LOC100377054.1.1,,,,,,,HNRH2_RAT,Rattus norvegicus (Rat), comp132105_c0_seq2,2119,42.3313,0.57407112,559,140,,5.00E-36,P31942,Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9),Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9),GO:0003723; GO:0000398; GO:0000166; GO:0005634; GO:0030529,"RNA binding; mRNA splicing, via spliceosome; nucleotide binding; nucleus; ribonucleoprotein complex",PF00076;,5.00E-87,CHOYP_LOC100377054.1.1,,,,,,,HNRH3_HUMAN,Homo sapiens (Human),"epithelial cell differentiation [GO:0030855]; mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]" comp132108_c0_seq3,843,43.4164,0.85852028,0,0,,6.00E-36,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp132108_c0_seq6,1066,39.4934,0.87161411,0,0,,3.00E-35,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp132109_c0_seq1,953,37.9853,0.82026806,207,1581,,2.00E-40,O95881,Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19),Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19),GO:0045454; GO:0005788; GO:0019153,cell redox homeostasis; endoplasmic reticulum lumen; protein-disulfide reductase (glutathione) activity,,6.00E-25,CHOYP_TXD12.1.1,,,,,,,TXD12_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236] comp132114_c2_seq3,775,27.7419,0.67151375,0,0,,,,,,,,,,,3.00E-13,ruditapes_c2399,,,,,,, comp132115_c0_seq1,1040,34.7115,1.13018902,4,124,,6.00E-48,O97341,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALM_SUBDO,Suberites domuncula (Sponge), comp132117_c1_seq1,478,40.1674,0.52545206,13,39,,1.00E-13,Q14669,E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (E3 ubiquitin-protein ligase for Arf) (ULF) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (E3 ubiquitin-protein ligase for Arf) (ULF) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),GO:0006281; GO:0005737; GO:0009790; GO:2000780; GO:1901315; GO:0005654; GO:0042787; GO:0006974; GO:0046966; GO:0004842,DNA repair; cytoplasm; embryo development; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; thyroid hormone receptor binding; ubiquitin-protein ligase activity,PF00632;,,,,,,,,,TRIPC_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp132117_c3_seq1,767,46.6754,0.65060352,0,14,,1.00E-11,P46937,Yorkie homolog (65 kDa Yes-associated protein) (YAP65),Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog),GO:0001076; GO:0008283; GO:0071480; GO:0003682; GO:0060242; GO:0005829; GO:0003143; GO:0035329; GO:0030216; GO:0048368; GO:0043066; GO:0030857; GO:0030903; GO:0005654; GO:0048339; GO:0090263; GO:0008284; GO:0046622; GO:0045944; GO:0010837; GO:0072091; GO:0006974; GO:0035019; GO:0003713; GO:0003714; GO:0005667; GO:0006367; GO:0044212; GO:0001570,RNA polymerase II transcription factor binding transcription factor activity; cell proliferation; cellular response to gamma radiation; chromatin binding; contact inhibition; cytosol; embryonic heart tube morphogenesis; hippo signaling cascade; keratinocyte differentiation; lateral mesoderm development; negative regulation of apoptotic process; negative regulation of epithelial cell differentiation; notochord development; nucleoplasm; paraxial mesoderm development; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell proliferation; positive regulation of organ growth; positive regulation of transcription from RNA polymerase II promoter; regulation of keratinocyte proliferation; regulation of stem cell proliferation; response to DNA damage stimulus; somatic stem cell maintenance; transcription coactivator activity; transcription corepressor activity; transcription factor complex; transcription initiation from RNA polymerase II promoter; transcription regulatory region DNA binding; vasculogenesis,PF00397;,,,,,,,,,YAP1_HUMAN,Homo sapiens (Human),bud elongation involved in lung branching [GO:0060449]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; embryonic heart tube morphogenesis [GO:0003143]; hippo signaling [GO:0035329]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of stem cell differentiation [GO:2000737]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; somatic stem cell population maintenance [GO:0035019]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vasculogenesis [GO:0001570] comp132117_c3_seq2,580,41.0345,0.33352568,2,0,,3.00E-09,P51592,E3 ubiquitin-protein ligase hyd (EC 6.3.2.-) (Protein hyperplastic discs),E3 ubiquitin-protein ligase hyd (EC 6.3.2.-) (Protein hyperplastic discs),GO:0003723; GO:0048749; GO:0005737; GO:0007455; GO:0008585; GO:0007446; GO:0007112; GO:0045879; GO:0005634; GO:0042787; GO:0030162; GO:0007289; GO:0004842; GO:0008270,RNA binding; compound eye development; cytoplasm; eye-antennal disc morphogenesis; female gonad development; imaginal disc growth; male meiosis cytokinesis; negative regulation of smoothened signaling pathway; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of proteolysis; spermatid nucleus differentiation; ubiquitin-protein ligase activity; zinc ion binding,PF11547;PF00632;PF00658;,,,,,,,,,HYD_DROME,Drosophila melanogaster (Fruit fly),compound eye development [GO:0048749]; eye-antennal disc morphogenesis [GO:0007455]; female gonad development [GO:0008585]; germ cell development [GO:0007281]; imaginal disc development [GO:0007444]; imaginal disc growth [GO:0007446]; male meiosis cytokinesis [GO:0007112]; negative regulation of smoothened signaling pathway [GO:0045879]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell proliferation [GO:0042127]; regulation of proteolysis [GO:0030162]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283] comp132117_c3_seq3,1552,44.4588,0.51009824,13,92,,0,Q2TAS2,E3 ubiquitin-protein ligase SMURF2 (EC 6.3.2.-) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2),E3 ubiquitin-protein ligase SMURF2 (EC 6.3.2.-) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2),GO:0005737; GO:0045121; GO:0005634; GO:0005886; GO:0004842,cytoplasm; membrane raft; nucleus; plasma membrane; ubiquitin-protein ligase activity,PF00168;PF00632;PF00397;,0,CHOYP_SMUF2.1.1,,,,,,,SMUF2_XENLA,Xenopus laevis (African clawed frog), comp132117_c3_seq4,664,46.8373,0.66666818,24,80,,2.00E-06,Q8L706,Synaptotagmin-5 (NTMC2T2.1) (Synaptotagmin E),Synaptotagmin-5 (NTMC2T2.1) (Synaptotagmin E),GO:0012505; GO:0005783; GO:0016021; GO:0008289; GO:0046872; GO:0005886; GO:0009506,endomembrane system; endoplasmic reticulum; integral to membrane; lipid binding; metal ion binding; plasma membrane; plasmodesma,PF00168;PF17047;,,,,,,,,,SYT5_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp132117_c3_seq5,351,37.037,0.34714286,1,0,,8.00E-08,Q9ULT8,E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),GO:0005737; GO:0046872; GO:0001843; GO:0005634; GO:0042787; GO:0004842,cytoplasm; metal ion binding; neural tube closure; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12796;PF00632;PF06701;PF07738;,3.00E-43,CHOYP_SMUF2.1.1,,,,,,,HECD1_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp132118_c0_seq5,569,37.4341,0.41319446,0,0,,,,,,,,,2.00E-21,CHOYP_NEMVEDRAFT_V1G197092.1.2,,,,,,,,, comp132120_c1_seq1,649,43.1433,0.5323518,14,149,,4.00E-52,Q2TBN5,COMM domain-containing protein 9,COMM domain-containing protein 9,,,PF07258;,2.00E-22,CHOYP_LOC100561410.1.1,,,,,,,COMD9_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; sodium ion transport [GO:0006814]; transcription, DNA-templated [GO:0006351]" comp132123_c0_seq1,219,46.1187,0.60440821,9,0,,,,,,,,,1.00E-19,CHOYP_BRAFLDRAFT_275787.1.2,,,,,,,,, comp132123_c3_seq1,1293,45.4756,0.49439663,80,17,,2.00E-96,Q9NR09,Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),GO:0005794; GO:0006915; GO:0051301; GO:0004869; GO:0005768; GO:0060711; GO:0016020; GO:0005815; GO:0030496; GO:0007067; GO:0043066; GO:2001237; GO:0008284; GO:0006468; GO:0042127; GO:0032465; GO:0000922; GO:0060712; GO:0005802; GO:0004842,Golgi apparatus; apoptotic process; cell division; cysteine-type endopeptidase inhibitor activity; endosome; labyrinthine layer development; membrane; microtubule organizing center; midbody; mitosis; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; positive regulation of cell proliferation; protein phosphorylation; regulation of cell proliferation; regulation of cytokinesis; spindle pole; spongiotrophoblast layer development; trans-Golgi network; ubiquitin-protein ligase activity,PF00653;PF12356;PF00179;,,,,,,,,,BIRC6_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] comp132123_c4_seq1,875,46.1714,0.40815179,47,25,,5.00E-13,Q50L39,Baculoviral IAP repeat-containing protein 5.2-A (Survivin2-A) (xSurvivin2A) (xSvv2/SIX) (xL_Survivin1) (Su1),Baculoviral IAP repeat-containing protein 5.2-A (Survivin2-A) (xSurvivin2A) (xSvv2/SIX) (xL_Survivin1) (Su1),GO:0051301; GO:0032133; GO:0007059; GO:0000777; GO:0005737; GO:0046872; GO:0030496; GO:0007067; GO:0043066; GO:0045892; GO:0005634; GO:0006468; GO:0046965; GO:0005819; GO:0001944,"cell division; chromosome passenger complex; chromosome segregation; condensed chromosome kinetochore; cytoplasm; metal ion binding; midbody; mitosis; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent; nucleus; protein phosphorylation; retinoid X receptor binding; spindle; vasculature development",PF00653;,4.00E-65,CHOYP_BIRC6.1.2,,,,,,,BI52A_XENLA,Xenopus laevis (African clawed frog),"cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; vasculature development [GO:0001944]" comp132123_c5_seq1,578,42.9066,0.49341347,32,18,,,,,,,,,5.00E-11,CHOYP_BIRC6.1.2,,,,,,,,, comp132124_c0_seq1,862,39.4432,0.57533411,695,1611,,6.00E-93,Q16740,"Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)","ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)",GO:0005524; GO:0005759; GO:0005739; GO:0008233; GO:0006508; GO:0004252,ATP binding; mitochondrial matrix; mitochondrion; peptidase activity; proteolysis; serine-type endopeptidase activity,PF00574;,1.00E-27,CHOYP_NEMVEDRAFT_V1G192713.1.1,,,,,,,CLPP_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp132125_c0_seq1,526,38.5932,0.93735517,0,0,,3.00E-11,Q6R7D0,Putative apoptosis inhibitor ORF99,Putative apoptosis inhibitor ORF99,,,PF00653;,,,,,,,,,IAP3_OSHVF,Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus), comp132125_c0_seq12,563,35.7016,0.84684952,0,0,,6.00E-11,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp132125_c0_seq3,638,33.6991,0.90350169,0,0,,3.00E-09,Q13075,Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),GO:0005524; GO:0016323; GO:0004869; GO:0005737; GO:0006954; GO:0045087; GO:0046872; GO:0043154; GO:0043524; GO:0007399; GO:0017111,ATP binding; basolateral plasma membrane; cysteine-type endopeptidase inhibitor activity; cytoplasm; inflammatory response; innate immune response; metal ion binding; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of neuron apoptotic process; nervous system development; nucleoside-triphosphatase activity,PF00653;,,,,,,,,,BIRC1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678] comp132125_c0_seq8,515,36.5049,0.88235627,0,0,,3.00E-11,Q6R7D0,Putative apoptosis inhibitor ORF99,Putative apoptosis inhibitor ORF99,,,PF00653;,,,,,,,,,IAP3_OSHVF,Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus), comp132125_c0_seq9,686,33.2362,0.86742609,0,0,,2.00E-10,Q13490,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (IAP-2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2),GO:0035631; GO:0038061; GO:0035666; GO:0007166; GO:0006921; GO:0005829; GO:0045087; GO:0009898; GO:0070266; GO:0043066; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0000209; GO:0039535; GO:0051726; GO:0045595; GO:0042127; GO:2000116; GO:0050727; GO:0060544; GO:0070424; GO:0034121; GO:0006355; GO:0034138; GO:0034142; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; NIK/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; cell surface receptor signaling pathway; cellular component disassembly involved in execution phase of apoptosis; cytosol; innate immune response; internal side of plasma membrane; necroptosis; negative regulation of apoptotic process; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of RIG-I signaling pathway; regulation of cell cycle; regulation of cell differentiation; regulation of cell proliferation; regulation of cysteine-type endopeptidase activity; regulation of inflammatory response; regulation of necroptosis; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of toll-like receptor signaling pathway; regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_HUMAN,Homo sapiens (Human),"cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp132132_c0_seq1,1270,35.3543,0.58066538,4,0,,1.00E-11,Q6AZT7,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0060271; GO:0060027; GO:0090090; GO:0072372; GO:2000095,"Wnt receptor signaling pathway; cilium morphogenesis; convergent extension involved in gastrulation; negative regulation of canonical Wnt receptor signaling pathway; primary cilium; regulation of Wnt receptor signaling pathway, planar cell polarity pathway",PF13374;PF13176;,,,,,,,,,NPHP3_XENLA,Xenopus laevis (African clawed frog),"cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]" comp132132_c0_seq2,1324,34.9698,0.56909463,10,20,,1.00E-11,Q6AZT7,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0060271; GO:0060027; GO:0090090; GO:0072372; GO:2000095,"Wnt receptor signaling pathway; cilium morphogenesis; convergent extension involved in gastrulation; negative regulation of canonical Wnt receptor signaling pathway; primary cilium; regulation of Wnt receptor signaling pathway, planar cell polarity pathway",PF13374;PF13176;,,,,,,,,,NPHP3_XENLA,Xenopus laevis (African clawed frog),"cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]" comp132134_c0_seq1,1491,40.3085,0.84462242,0,28,,1.00E-28,O64989,Cytochrome P450 90B1 (EC 1.14.-.-) (Protein DWARF 4) (Dwarf4) (Steroid 22-alpha-hydroxylase),Cytochrome P450 90B1 (EC 1.14.-.-) (Protein DWARF 4) (Dwarf4) (Steroid 22-alpha-hydroxylase),GO:0016132; GO:0005783; GO:0020037; GO:0016021; GO:0005506; GO:0009867; GO:0010358; GO:0016705; GO:0009741; GO:0010012; GO:0009826,"brassinosteroid biosynthetic process; endoplasmic reticulum; heme binding; integral to membrane; iron ion binding; jasmonic acid mediated signaling pathway; leaf shaping; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; response to brassinosteroid stimulus; steroid 22-alpha hydroxylase activity; unidimensional cell growth",PF00067;,,,,,,,,,C90B1_ARATH,Arabidopsis thaliana (Mouse-ear cress),brassinosteroid biosynthetic process [GO:0016132]; brassinosteroid homeostasis [GO:0010268]; jasmonic acid mediated signaling pathway [GO:0009867]; leaf development [GO:0048366]; leaf shaping [GO:0010358]; response to brassinosteroid [GO:0009741]; response to jasmonic acid [GO:0009753]; sterol metabolic process [GO:0016125]; unidimensional cell growth [GO:0009826] comp132134_c0_seq4,1255,40.6375,0.87308508,0,9,,8.00E-26,Q7XU38,Cytochrome P450 87A3 (EC 1.14.-.-),Cytochrome P450 87A3 (EC 1.14.-.-),GO:0030659; GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705,"cytoplasmic vesicle membrane; heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C87A3_ORYSJ,Oryza sativa subsp. japonica (Rice),brassinosteroid biosynthetic process [GO:0016132]; brassinosteroid homeostasis [GO:0010268]; multicellular organism development [GO:0007275]; sterol metabolic process [GO:0016125] comp132134_c0_seq5,1326,40.6486,0.89823231,0,4,,2.00E-62,Q08D50,Cytochrome P450 26B1 (EC 1.14.-.-),Cytochrome P450 26B1 (EC 1.14.13.-),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP26B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),retinoic acid catabolic process [GO:0034653] comp132135_c0_seq2,1654,32.2249,0.33318965,58,100,,9.00E-20,A8KB59,Coiled-coil domain-containing protein 153,Coiled-coil domain-containing protein 153,,,,,,,,,,,,CC153_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp132136_c0_seq1,876,35.3881,0.30116797,134,1221,,5.00E-10,P25867,Ubiquitin-conjugating enzyme E2-17 kDa (EC 6.3.2.19) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0051276; GO:0001751; GO:0008054; GO:0048132; GO:0030718; GO:0007140; GO:0005875; GO:0007067; GO:0016322; GO:0045676; GO:0031647; GO:0007286; GO:0004842,ATP binding; chromosome organization; compound eye photoreceptor cell differentiation; cyclin catabolic process; female germ-line stem cell division; germ-line stem cell maintenance; male meiosis; microtubule associated complex; mitosis; neuron remodeling; regulation of R7 cell differentiation; regulation of protein stability; spermatid development; ubiquitin-protein ligase activity,PF00179;,8.00E-17,CHOYP_UBC2.2.3,,,,,,,UBCD1_DROME,Drosophila melanogaster (Fruit fly),chromosome organization [GO:0051276]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; female germ-line stem cell asymmetric division [GO:0048132]; germ-line stem cell population maintenance [GO:0030718]; male meiosis [GO:0007140]; mitotic nuclear division [GO:0007067]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; neurogenesis [GO:0022008]; neuron remodeling [GO:0016322]; oogenesis [GO:0048477]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of protein stability [GO:0031647]; regulation of R7 cell differentiation [GO:0045676]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511] comp132138_c0_seq2,521,34.9328,0.83397137,0,0,,,,,,,,,,,4.00E-15,ruditapes2_c2711,,,,,,, comp132138_c0_seq4,526,33.8403,0.5500346,0,0,,,,,,,,,,,2.00E-18,ruditapes_c29520,,,,,,, comp132141_c1_seq1,729,40.192,0.38781103,0,0,,3.00E-19,Q7TN31,Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q),Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q),GO:0001525; GO:0007155; GO:0030154; GO:0005576; GO:0003676; GO:0048471; GO:0045766; GO:0001938,angiogenesis; cell adhesion; cell differentiation; extracellular region; nucleic acid binding; perinuclear region of cytoplasm; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation,PF00498;PF01585;,6.00E-24,CHOYP_AGGF1.1.1,1.00E-43,ruditapes_c24746,,,,,AGGF1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; mRNA processing [GO:0006397]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of RNA splicing [GO:0043484]; vasculogenesis [GO:0001570] comp132141_c1_seq2,1120,41.4286,0.53210721,1,0,,2.00E-08,Q6DDU9,RNA-binding protein 5-B (RNA-binding motif protein 5-B),RNA-binding protein 5-B (RNA-binding motif protein 5-B),GO:0003729; GO:0000166; GO:0005634; GO:0043065; GO:0000381; GO:0005681; GO:0000245; GO:0008270,"mRNA binding; nucleotide binding; nucleus; positive regulation of apoptotic process; regulation of alternative mRNA splicing, via spliceosome; spliceosomal complex; spliceosomal complex assembly; zinc ion binding",PF01585;PF00076;PF00641;,,,,,,,,,RBM5B_XENLA,Xenopus laevis (African clawed frog),"positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245]" comp132141_c1_seq3,1467,39.9455,0.51469563,9,34,,5.00E-62,Q7TN31,Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q),Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q),GO:0001525; GO:0007155; GO:0030154; GO:0005576; GO:0003676; GO:0048471; GO:0045766; GO:0001938,angiogenesis; cell adhesion; cell differentiation; extracellular region; nucleic acid binding; perinuclear region of cytoplasm; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation,PF00498;PF01585;,,,,,,,,,AGGF1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; mRNA processing [GO:0006397]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of RNA splicing [GO:0043484]; vasculogenesis [GO:0001570] comp132146_c1_seq1,271,42.8044,0.33333787,3,0,,1.00E-22,Q6ZRF8,RING finger protein 207,RING finger protein 207,GO:0005622; GO:0008270,intracellular; zinc ion binding,PF00643;PF00097;,,,,,,,,,RN207_HUMAN,Homo sapiens (Human),cell-cell signaling involved in cardiac conduction [GO:0086019]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of gene expression [GO:0010628]; positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [GO:1903954]; positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903762]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart looping [GO:1901207] comp132146_c2_seq1,1250,42,0.50040032,43,108,,9.00E-13,A0JNG4,RING finger protein 207,RING finger protein 207,GO:0005622; GO:0008270,intracellular; zinc ion binding,PF00643;PF00097;,,,,,,,,,RN207_BOVIN,Bos taurus (Bovine), comp132147_c1_seq1,645,43.1008,1.17120199,6,10,,4.00E-37,B8DH16,Glutamine amidotransferase subunit PdxT (EC 2.6.-.-) (Glutamine amidotransferase glutaminase subunit PdxT),Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2),GO:0006543; GO:0042823; GO:0016740,glutamine catabolic process; pyridoxal phosphate biosynthetic process; transferase activity,PF01174;,,,,,,,,,PDXT_LISMH,Listeria monocytogenes serotype 4a (strain HCC23),glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819] comp132147_c1_seq2,493,43.6105,0.94504737,2,5,,3.00E-33,Q929R8,Glutamine amidotransferase subunit PdxT (EC 2.6.-.-) (Glutamine amidotransferase glutaminase subunit PdxT),Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2),GO:0006543; GO:0042823; GO:0016740,glutamine catabolic process; pyridoxal phosphate biosynthetic process; transferase activity,PF01174;,3.00E-32,CHOYP_NEMVEDRAFT_V1G175375.1.1,2.00E-39,ruditapes_c7508,,,,,PDXT_LISIN,Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262),glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819] comp132147_c1_seq3,716,42.0391,1.13990683,0,0,,8.00E-37,B8DH16,Glutamine amidotransferase subunit PdxT (EC 2.6.-.-) (Glutamine amidotransferase glutaminase subunit PdxT),Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2),GO:0006543; GO:0042823; GO:0016740,glutamine catabolic process; pyridoxal phosphate biosynthetic process; transferase activity,PF01174;,,,,,,,,,PDXT_LISMH,Listeria monocytogenes serotype 4a (strain HCC23),glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819] comp132160_c0_seq1,1449,44.9965,0.99675173,310,1229,,6.00E-67,P09954,Carboxypeptidase A1 (EC 3.4.17.1),Carboxypeptidase A1 (EC 3.4.17.1),GO:0005576; GO:0004181; GO:0006508; GO:0008270,extracellular region; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;PF02244;,,,2.00E-13,ruditapes_c1586,,,,,CBPA1_PIG,Sus scrofa (Pig), comp132161_c0_seq1,752,29.6543,0.24444127,4,0,,,,,,,,,,,2.00E-34,ruditapes2_c959,,,,,,, comp132163_c0_seq1,2091,39.3592,0.57187015,29,61,,2.00E-53,Q60738,Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1),Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1),GO:0030315; GO:0070574; GO:0019855; GO:0070509; GO:0006874; GO:0006882; GO:0071585; GO:0001701; GO:0016021; GO:0090281; GO:0046929; GO:0071584; GO:0005886; GO:0005385,T-tubule; cadmium ion transmembrane transport; calcium channel inhibitor activity; calcium ion import; cellular calcium ion homeostasis; cellular zinc ion homeostasis; detoxification of cadmium ion; in utero embryonic development; integral to membrane; negative regulation of calcium ion import; negative regulation of neurotransmitter secretion; negative regulation of zinc ion transmembrane import; plasma membrane; zinc ion transmembrane transporter activity,PF01545;,,,,,,,,,ZNT1_MOUSE,Mus musculus (Mouse),cadmium ion transmembrane transport [GO:0070574]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular zinc ion homeostasis [GO:0006882]; detoxification of cadmium ion [GO:0071585]; in utero embryonic development [GO:0001701]; negative regulation of calcium ion import [GO:0090281]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of zinc ion transmembrane import [GO:0071584]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829] comp132163_c0_seq2,1720,41.5698,0.50164667,0,9,,3.00E-56,P32798,Cobalt uptake protein COT1,Cobalt uptake protein COT1,GO:0006882; GO:0015087; GO:0000324; GO:0016021; GO:0031966; GO:0005385,cellular zinc ion homeostasis; cobalt ion transmembrane transporter activity; fungal-type vacuole; integral to membrane; mitochondrial membrane; zinc ion transmembrane transporter activity,PF01545;,2.00E-92,CHOYP_LOC100677972.1.1,,,,,,,COT1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829] comp132164_c0_seq1,1089,39.4858,0.24149258,0,0,,2.00E-15,B4F6Q9,Oxidation resistance protein 1,Oxidation resistance protein 1,GO:0016998; GO:0005739; GO:0006950,cell wall macromolecule catabolic process; mitochondrion; response to stress,PF01476;PF07534;,8.00E-56,CHOYP_K1609.1.1,,,,,,,OXR1_XENLA,Xenopus laevis (African clawed frog), comp132164_c0_seq4,1399,39.5997,0.28077508,0,0,,5.00E-72,Q6DDZ9,TLD domain-containing protein 1 (TBC/LysM-associated domain-containing protein 1),TLD domain-containing protein 1 (TBC/LysM-associated domain-containing protein 1),,,PF07534;,,,,,,,,,K1609_XENLA,Xenopus laevis (African clawed frog), comp132177_c0_seq1,1348,34.4955,0.36205066,82,116,,3.00E-46,Q6GMA4,Charged multivesicular body protein 6-A (Chromatin-modifying protein 6-A),Charged multivesicular body protein 6-A (Chromatin-modifying protein 6-A),GO:0012505; GO:0031902; GO:0015031,endomembrane system; late endosome membrane; protein transport,PF03357;,4.00E-73,CHOYP_LOC100533291.4.7,,,,,,,CHM6A_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp132180_c1_seq1,1185,37.384,0.27872515,0,4,,7.00E-78,Q5E9T4,Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine pyrophosphokinase 1),Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine pyrophosphokinase 1),GO:0005524; GO:0016301; GO:0009229; GO:0004788; GO:0006772,ATP binding; kinase activity; thiamine diphosphate biosynthetic process; thiamine diphosphokinase activity; thiamine metabolic process,PF04265;PF04263;,,,,,,,,,TPK1_BOVIN,Bos taurus (Bovine),thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772] comp132182_c2_seq2,1509,35.3877,0.53990298,45,90,,2.00E-12,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132185_c0_seq2,738,41.1924,0.83601076,5,63,,,,,,,,,3.00E-15,CHOYP_LOC100639626.1.1,4.00E-43,ruditapes_lrc32425,,,,,,, comp132187_c0_seq2,1214,42.9984,0.30727026,1,39,,2.00E-08,O69060,Probable alpha-ketoglutarate-dependent hypophosphite dioxygenase (EC 1.-.-.-),Probable alpha-ketoglutarate-dependent hypophosphite dioxygenase (EC 1.-.-.-),GO:0051213,dioxygenase activity,PF05721;,4.00E-123,CHOYP_LOC100640618.1.1,,,,,,,HTXA_PSEST,Pseudomonas stutzeri (Pseudomonas perfectomarina), comp132187_c0_seq4,723,45.0899,0.24938811,0,16,,2.00E-06,Q9NAM7,Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog (EC 1.-.-.-),Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog (EC 1.-.-.-),GO:0051213; GO:0046872,dioxygenase activity; metal ion binding,PF05721;,,,,,,,,,PHYD1_CAEEL,Caenorhabditis elegans, comp132190_c1_seq2,296,45.6081,0.6623626,8,18,,6.00E-13,Q58NQ5,Zinc finger protein PLAG1 (Pleiomorphic adenoma gene 1 protein),Zinc finger protein PLAG1 (Pleiomorphic adenoma gene 1 protein),GO:0003677; GO:0022612; GO:0046872; GO:0035264; GO:0010629; GO:0005634; GO:0035265; GO:0010628; GO:0060252; GO:0060736; GO:0000981,DNA binding; gland morphogenesis; metal ion binding; multicellular organism growth; negative regulation of gene expression; nucleus; organ growth; positive regulation of gene expression; positive regulation of glial cell proliferation; prostate gland growth; sequence-specific DNA binding RNA polymerase II transcription factor activity,,,,,,,,,,PLAG1_CHICK,Gallus gallus (Chicken),gland morphogenesis [GO:0022612]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; positive regulation of glial cell proliferation [GO:0060252]; prostate gland growth [GO:0060736] comp132195_c0_seq1,854,43.5597,1.23583657,70,119,,1.00E-35,P97603,Neogenin (Fragment),Neogenin (Fragment),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;PF13895;PF06583;,,,,,,,,,NEO1_RAT,Rattus norvegicus (Rat),axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; negative regulation of neuron death [GO:1901215]; positive regulation of BMP signaling pathway [GO:0030513] comp132200_c1_seq1,1434,43.6541,1.06194742,2,281,female>male,2.00E-11,Q3SZR9,Tetraspanin-3 (Tspan-3),Tetraspanin-3 (Tspan-3),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN3_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166] comp132201_c0_seq1,821,43.4836,0.92910656,127,154,,1.00E-17,Q60989,E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),GO:0016055; GO:0005737; GO:0005829; GO:1990001; GO:0043066; GO:0043524; GO:0051402; GO:0005634; GO:0048471; GO:0043234; GO:0004842; GO:0008270,Wnt receptor signaling pathway; cytoplasm; cytosol; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; neuron apoptotic process; nucleus; perinuclear region of cytoplasm; protein complex; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,XIAP_MOUSE,Mus musculus (Mouse),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055] comp132201_c0_seq2,782,43.8619,0.90520379,43,106,,1.00E-23,A9JTP3,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIRC7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966] comp132203_c0_seq1,457,36.7615,0.93103393,36,30,,,,,,,,,,,1.00E-14,ruditapes_c29143,,,,,,, comp132203_c1_seq1,849,41.3428,0.50117994,13,23,,7.00E-47,Q6NWZ9,Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I),Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I),GO:0046439; GO:0017172; GO:0005506; GO:0042412,L-cysteine metabolic process; cysteine dioxygenase activity; iron ion binding; taurine biosynthetic process,PF05995;,,,,,,,,,CDO1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"L-cysteine catabolic process to pyruvate, using cysteine dioxygenase [GO:0019451]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412]" comp132203_c1_seq2,836,41.5072,0.50506274,8,23,,9.00E-26,Q5RLY7,Cysteine dioxygenase (CDO) (EC 1.13.11.20),Cysteine dioxygenase (CDO) (EC 1.13.11.20),GO:0046439; GO:0017172; GO:0005506; GO:0042412,L-cysteine metabolic process; cysteine dioxygenase activity; iron ion binding; taurine biosynthetic process,PF05995;,6.00E-37,CHOYP_CDO1.1.4,8.00E-46,ruditapes_c9940,,,,,CDO_AJECG,Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432) (Darling's disease fungus) (Histoplasma capsulatum),taurine biosynthetic process [GO:0042412] comp132206_c0_seq3,2450,36.3673,0.27169668,22,72,,6.00E-67,P57113,Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18),Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18),GO:0006559; GO:0004364; GO:0016034; GO:0005739; GO:0006572,L-phenylalanine catabolic process; glutathione transferase activity; maleylacetoacetate isomerase activity; mitochondrion; tyrosine catabolic process,PF14497;PF02798;,,,,,,,,,MAAI_RAT,Rattus norvegicus (Rat),glutathione metabolic process [GO:0006749]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp132209_c0_seq1,2759,40.1232,0.48214857,4697,15088,,0,P30946,Heat shock protein HSP 90-alpha,Heat shock protein HSP 90-alpha,GO:0005524; GO:0016887; GO:0051131; GO:0042470; GO:0030235; GO:0045429; GO:0006457; GO:0045040; GO:0006950,ATP binding; ATPase activity; chaperone-mediated protein complex assembly; melanosome; nitric-oxide synthase regulator activity; positive regulation of nitric oxide biosynthetic process; protein folding; protein import into mitochondrial outer membrane; response to stress,PF02518;PF00183;,0,CHOYP_HSP90AA1.1.1,,,,,,,HS90A_RABIT,Oryctolagus cuniculus (Rabbit),protein folding [GO:0006457]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408] comp132209_c0_seq2,2745,40.1093,0.4849974,5766,19431,,0,Q61W58,Heat shock protein 90 (Abnormal dauer formation protein 21),Heat shock protein 90 (Abnormal dauer formation protein 21),GO:0005524; GO:0007049; GO:0048471; GO:0006457; GO:0006950,ATP binding; cell cycle; perinuclear region of cytoplasm; protein folding; response to stress,PF02518;PF00183;,0,CHOYP_HS90A.3.3,0,ruditapes_c846,,,,,HSP90_CAEBR,Caenorhabditis briggsae,cell cycle [GO:0007049]; protein folding [GO:0006457]; response to stress [GO:0006950] comp132211_c0_seq1,715,38.3217,0.65272543,27,296,,1.00E-33,P30047,GTP cyclohydrolase 1 feedback regulatory protein (GFRP) (GTP cyclohydrolase I feedback regulatory protein) (p35),GTP cyclohydrolase 1 feedback regulatory protein (GFRP) (GTP cyclohydrolase I feedback regulatory protein) (p35),GO:0016597; GO:0005829; GO:0030425; GO:0004857; GO:0042470; GO:0043105; GO:0009890; GO:0042133; GO:0006809; GO:0031965; GO:0043234; GO:0051291; GO:0050999; GO:0044281,amino acid binding; cytosol; dendrite; enzyme inhibitor activity; melanosome; negative regulation of GTP cyclohydrolase I activity; negative regulation of biosynthetic process; neurotransmitter metabolic process; nitric oxide biosynthetic process; nuclear membrane; protein complex; protein heterooligomerization; regulation of nitric-oxide synthase activity; small molecule metabolic process,PF06399;,,,,,,,,,GFRP_HUMAN,Homo sapiens (Human),negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; neurotransmitter metabolic process [GO:0042133]; nitric oxide biosynthetic process [GO:0006809]; protein heterooligomerization [GO:0051291]; regulation of nitric-oxide synthase activity [GO:0050999] comp132212_c0_seq1,2929,39.5698,0.35804769,3482,31385,,0,P52292,Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha),Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha),GO:0006259; GO:0006607; GO:0019221; GO:0005829; GO:0000085; GO:0019048; GO:0008139; GO:0005654; GO:0008565; GO:0000018,DNA metabolic process; NLS-bearing protein import into nucleus; cytokine-mediated signaling pathway; cytosol; mitotic G2 phase; modulation by virus of host morphology or physiology; nuclear localization sequence binding; nucleoplasm; protein transporter activity; regulation of DNA recombination,PF00514;PF16186;PF01749;,6.00E-177,CHOYP_IMA2.2.2,,,,,,,IMA2_HUMAN,Homo sapiens (Human),DNA metabolic process [GO:0006259]; intracellular transport of virus [GO:0075733]; modulation by virus of host process [GO:0019054]; NLS-bearing protein import into nucleus [GO:0006607]; regulation of DNA recombination [GO:0000018] comp132214_c0_seq1,885,46.3277,0.61192295,7,0,,1.00E-06,Q8VHK1,Caskin-2,Caskin-2,GO:0005737,cytoplasm,PF12796;PF16632;PF00536;PF07653;,,,,,,,,,CSKI2_MOUSE,Mus musculus (Mouse),signal transduction [GO:0007165] comp132214_c0_seq2,808,44.5545,0.60345081,3,24,,5.00E-31,Q8C0J6,Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C),Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C),,,PF12796;,2.00E-42,CHOYP_LOC410299.1.1,,,,,,,SWAHC_MOUSE,Mus musculus (Mouse), comp132218_c0_seq2,1284,35.7477,0.60840439,52,61,,7.00E-20,Q9Y2H0,Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4),Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4),GO:0007267; GO:0016020; GO:0045202,cell-cell signaling; membrane; synapse,PF03359;,,,,,,,,,DLGP4_HUMAN,Homo sapiens (Human),signaling [GO:0023052] comp132224_c0_seq1,1141,38.5627,0.3350099,26,196,,3.00E-35,Q9UBN7,Histone deacetylase 6 (HD6) (EC 3.5.1.98),Histone deacetylase 6 (HD6) (EC 3.5.1.98),GO:0070846; GO:0051879; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016235; GO:0070842; GO:0043014; GO:0005901; GO:0031252; GO:0070301; GO:0071218; GO:0035967; GO:0005881; GO:0005829; GO:0070840; GO:0019899; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0032418; GO:0016236; GO:0005874; GO:0005875; GO:0008017; GO:0006515; GO:0010727; GO:0007026; GO:0051354; GO:0043242; GO:0045861; GO:0045892; GO:0034983; GO:0048471; GO:0031593; GO:0070845; GO:0090035; GO:0010634; GO:1901300; GO:0010870; GO:0009967; GO:0043241; GO:0000209; GO:0060765; GO:0070201; GO:0060632; GO:0010469; GO:0070848; GO:0051788; GO:0009636; GO:0048156; GO:0006351; GO:0042903; GO:0043162; GO:0008270,"Hsp90 deacetylation; Hsp90 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); aggresome; aggresome assembly; alpha-tubulin binding; caveola; cell leading edge; cellular response to hydrogen peroxide; cellular response to misfolded protein; cellular response to topologically incorrect protein; cytoplasmic microtubule; cytosol; dynein complex binding; enzyme binding; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; lysosome localization; macroautophagy; microtubule; microtubule associated complex; microtubule binding; misfolded or incompletely synthesized protein catabolic process; negative regulation of hydrogen peroxide metabolic process; negative regulation of microtubule depolymerization; negative regulation of oxidoreductase activity; negative regulation of protein complex disassembly; negative regulation of proteolysis; negative regulation of transcription, DNA-dependent; peptidyl-lysine deacetylation; perinuclear region of cytoplasm; polyubiquitin binding; polyubiquitinated misfolded protein transport; positive regulation of chaperone-mediated protein complex assembly; positive regulation of epithelial cell migration; positive regulation of hydrogen peroxide-mediated programmed cell death; positive regulation of receptor biosynthetic process; positive regulation of signal transduction; protein complex disassembly; protein polyubiquitination; regulation of androgen receptor signaling pathway; regulation of establishment of protein localization; regulation of microtubule-based movement; regulation of receptor activity; response to growth factor stimulus; response to misfolded protein; response to toxic substance; tau protein binding; transcription, DNA-dependent; tubulin deacetylase activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; zinc ion binding",PF00850;PF02148;,8.00E-12,CHOYP_LOC100877749.1.1,,,,,,,HDAC6_HUMAN,Homo sapiens (Human),"aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; organelle organization [GO:0006996]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of microtubule-based movement [GO:0060632]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]" comp132224_c1_seq1,303,44.2244,0.47415846,8,0,,7.00E-10,Q9Z2V5,Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2),Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2),GO:0070846; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016235; GO:0070842; GO:0048487; GO:0005901; GO:0031252; GO:0070301; GO:0071218; GO:0005881; GO:0005829; GO:0030286; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0032418; GO:0016236; GO:0008017; GO:0006515; GO:0007026; GO:0045861; GO:0005634; GO:0034983; GO:0048471; GO:0070845; GO:0090035; GO:0010634; GO:1901300; GO:0010870; GO:0009967; GO:0043241; GO:0000209; GO:0070201; GO:0010469; GO:0006355; GO:0070848; GO:0009636; GO:0006351; GO:0042903; GO:0043130; GO:0043162; GO:0008270,"Hsp90 deacetylation; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); aggresome; aggresome assembly; beta-tubulin binding; caveola; cell leading edge; cellular response to hydrogen peroxide; cellular response to misfolded protein; cytoplasmic microtubule; cytosol; dynein complex; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; lysosome localization; macroautophagy; microtubule binding; misfolded or incompletely synthesized protein catabolic process; negative regulation of microtubule depolymerization; negative regulation of proteolysis; nucleus; peptidyl-lysine deacetylation; perinuclear region of cytoplasm; polyubiquitinated misfolded protein transport; positive regulation of chaperone-mediated protein complex assembly; positive regulation of epithelial cell migration; positive regulation of hydrogen peroxide-mediated programmed cell death; positive regulation of receptor biosynthetic process; positive regulation of signal transduction; protein complex disassembly; protein polyubiquitination; regulation of establishment of protein localization; regulation of receptor activity; regulation of transcription, DNA-dependent; response to growth factor stimulus; response to toxic substance; transcription, DNA-dependent; tubulin deacetylase activity; ubiquitin binding; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; zinc ion binding",PF00850;PF02148;,,,,,,,,,HDAC6_MOUSE,Mus musculus (Mouse),"aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]" comp132226_c0_seq1,1308,39.2966,0.17875741,37,225,,3.00E-133,Q9NUQ7,Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-),Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-),GO:0005783; GO:0005634; GO:0006508; GO:0019783; GO:0016790,endoplasmic reticulum; nucleus; proteolysis; small conjugating protein-specific protease activity; thiolester hydrolase activity,PF07910;,2.00E-84,CHOYP_UFSP2.1.1,,,,,,,UFSP2_HUMAN,Homo sapiens (Human),proteolysis [GO:0006508]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146] comp132235_c0_seq1,1754,41.2201,0.31428582,30,62,,2.00E-50,Q8IWJ2,GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53),GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53),GO:0005794; GO:0090161; GO:0034499; GO:0016020; GO:0034453; GO:0031023; GO:0005634; GO:0034067; GO:0000042; GO:0006622; GO:0071955; GO:0070861; GO:0005802,Golgi apparatus; Golgi ribbon formation; late endosome to Golgi transport; membrane; microtubule anchoring; microtubule organizing center organization; nucleus; protein localization to Golgi apparatus; protein targeting to Golgi; protein targeting to lysosome; recycling endosome to Golgi transport; regulation of protein exit from endoplasmic reticulum; trans-Golgi network,PF01465;PF16704;,2.00E-41,CHOYP_GCC2.1.1,,,,,,,GCC2_HUMAN,Homo sapiens (Human),"Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]" comp132235_c0_seq2,1202,44.426,0.38053017,13,17,,1.00E-51,Q8IWJ2,GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53),GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53),GO:0005794; GO:0090161; GO:0034499; GO:0016020; GO:0034453; GO:0031023; GO:0005634; GO:0034067; GO:0000042; GO:0006622; GO:0071955; GO:0070861; GO:0005802,Golgi apparatus; Golgi ribbon formation; late endosome to Golgi transport; membrane; microtubule anchoring; microtubule organizing center organization; nucleus; protein localization to Golgi apparatus; protein targeting to Golgi; protein targeting to lysosome; recycling endosome to Golgi transport; regulation of protein exit from endoplasmic reticulum; trans-Golgi network,PF01465;PF16704;,,,,,,,,,GCC2_HUMAN,Homo sapiens (Human),"Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]" comp132243_c0_seq1,1260,41.2698,0.22577002,51,43,,3.00E-17,Q14527,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),GO:0005524; GO:0016887; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005654; GO:0005634; GO:0016567; GO:0006357; GO:0006355; GO:0006351; GO:0008270,"ATP binding; ATPase activity; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleoplasm; nucleus; protein ubiquitination; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,7.00E-13,CHOYP_HLTF.1.1,,,,,,,HLTF_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription, DNA-templated [GO:0006355]" comp132244_c0_seq1,1353,41.02,0.38682721,64,217,,2.00E-29,A0JMU5,Putative protein arginine N-methyltransferase 10 (EC 2.1.1.-),Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-),GO:0005737; GO:0008276,cytoplasm; protein methyltransferase activity,,,,,,,,,,ANM10_XENLA,Xenopus laevis (African clawed frog),protein methylation [GO:0006479] comp132248_c0_seq1,1151,39.3571,0.45533631,3043,12475,,3.00E-147,Q9Z2U1,Proteasome subunit alpha type-5 (EC 3.4.25.1) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain),Proteasome subunit alpha type-5 (EC 3.4.25.1) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain),GO:0005829; GO:0005634; GO:0005839; GO:0019773; GO:0004298; GO:0006511,"cytosol; nucleus; proteasome core complex; proteasome core complex, alpha-subunit complex; threonine-type endopeptidase activity; ubiquitin-dependent protein catabolic process",PF00227;PF10584;,3.00E-176,CHOYP_NEMVEDRAFT_V1G168163.1.1,0,ruditapes2_c2161,2.00E-177,AM856889.p.cg.6,9,,PSA5_MOUSE,Mus musculus (Mouse),"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp132256_c1_seq1,691,44.4284,0.35252239,22,61,,3.00E-36,P47264,Uncharacterized ATP-dependent helicase MG018 (EC 3.6.4.-),Uncharacterized ATP-dependent helicase MG018 (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0004386; GO:0008270,ATP binding; DNA binding; helicase activity; zinc ion binding,PF00271;PF00176;PF04434;,8.00E-130,CHOYP_BTAF1.2.2,,,,,,,Y018_MYCGE,Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195), comp132256_c2_seq1,1178,43.6333,0.28771469,41,191,,1.00E-150,O14981,TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),GO:0005524; GO:0003677; GO:0004386; GO:0045892; GO:0005634; GO:0003700,"ATP binding; DNA binding; helicase activity; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity",PF12054;PF00271;PF00176;,,,,,,,,,BTAF1_HUMAN,Homo sapiens (Human),"negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]" comp132257_c0_seq1,795,38.1132,0.72836717,656,8480,,5.00E-28,P61917,Epididymal secretory protein E1 (EPI-1) (Niemann Pick type C2 protein homolog),Epididymal secretory protein E1 (EPI-1) (Niemann Pick type C2 protein homolog),GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0005783; GO:0005576; GO:0032367; GO:0005764; GO:0009615,cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; endoplasmic reticulum; extracellular region; intracellular cholesterol transport; lysosome; response to virus,PF02221;,,,,,,,,,NPC2_PANTR,Pan troglodytes (Chimpanzee),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; response to virus [GO:0009615] comp132262_c0_seq1,1374,44.2504,0.33534001,43,217,,4.00E-68,Q8CI66,Stomatin-like protein 1 (SLP-1),Stomatin-like protein 1 (SLP-1),GO:0016021; GO:0032934,integral to membrane; sterol binding,PF01145;PF02036;,3.00E-11,CHOYP_LOC579579.1.1,,,,,,,STML1_MOUSE,Mus musculus (Mouse),negative regulation of acid-sensing ion channel activity [GO:1901586]; SMAD protein signal transduction [GO:0060395] comp132262_c1_seq2,710,40.9859,0.53736526,13,7,,7.00E-32,Q6DED9,Transmembrane protein C5orf28 homolog,Transmembrane protein C5orf28 homolog,GO:0016021,integral to membrane,,,,,,,,,,CE028_XENLA,Xenopus laevis (African clawed frog), comp132266_c0_seq4,810,36.4198,0.61334939,3,0,,2.00E-15,Q67ZM4,Actin-depolymerizing factor 7 (ADF-7) (AtADF7),Actin-depolymerizing factor 7 (ADF-7) (AtADF7),GO:0005884; GO:0030042,actin filament; actin filament depolymerization,PF00241;,,,,,,,,,ADF7_ARATH,Arabidopsis thaliana (Mouse-ear cress),actin filament depolymerization [GO:0030042] comp132268_c0_seq1,787,42.5667,0.95515306,108,6758,,1.00E-21,P47845,Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (IgE-binding protein) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen),Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (IgE-binding protein) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen),GO:0008380; GO:0030246; GO:0030154; GO:0031012; GO:0005576; GO:0045087; GO:0006397; GO:0005743; GO:0005681,RNA splicing; carbohydrate binding; cell differentiation; extracellular matrix; extracellular region; innate immune response; mRNA processing; mitochondrial inner membrane; spliceosomal complex,PF00337;,,,,,,,,,LEG3_RABIT,Oryctolagus cuniculus (Rabbit),eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neutrophil chemotaxis [GO:0030593]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380] comp132271_c0_seq1,1023,39.0029,0.51208134,47,271,,7.00E-63,Q6NUB2,Protein CWC15 homolog A,Protein CWC15 homolog A,GO:0003723; GO:0000398; GO:0005634; GO:0005681,"RNA binding; mRNA splicing, via spliceosome; nucleus; spliceosomal complex",PF04889;,1.00E-117,CHOYP_LOC592411.1.1,,,,,,,CW15A_XENLA,Xenopus laevis (African clawed frog),"mRNA splicing, via spliceosome [GO:0000398]" comp132271_c0_seq2,1036,40.0579,0.38598051,0,0,,7.00E-35,Q6NUB2,Protein CWC15 homolog A,Protein CWC15 homolog A,GO:0003723; GO:0000398; GO:0005634; GO:0005681,"RNA binding; mRNA splicing, via spliceosome; nucleus; spliceosomal complex",PF04889;,,,,,,,,,CW15A_XENLA,Xenopus laevis (African clawed frog),"mRNA splicing, via spliceosome [GO:0000398]" comp132276_c0_seq1,1732,42.1478,0.44388712,669,1440,,4.00E-95,Q9I7M2,GTP-binding protein 10 homolog,GTP-binding protein 10 homolog,GO:0005525; GO:0006184; GO:0003924; GO:0000287; GO:0005730; GO:0042254,GTP binding; GTP catabolic process; GTPase activity; magnesium ion binding; nucleolus; ribosome biogenesis,PF01018;PF01926;,1.00E-42,CHOYP_HACL1.1.1,,,,,,,GTPBA_DROME,Drosophila melanogaster (Fruit fly),ribosome biogenesis [GO:0042254] comp132282_c0_seq1,1553,40.7598,0.59540255,0,18,,,,,,,,,7.00E-78,CHOYP_LOC100867628.1.1,,,,,,,,, comp132282_c0_seq3,1873,42.1249,0.560101,17,42,,,,,,,,,1.00E-107,CHOYP_LOC100867628.1.1,,,,,,,,, comp132284_c0_seq1,956,43.2008,0.29558122,22,95,,1.00E-31,Q66H85,Ankyrin repeat and zinc finger domain-containing protein 1,Ankyrin repeat and zinc finger domain-containing protein 1,GO:0046872,metal ion binding,PF00023;,9.00E-42,CHOYP_ANKZF1.1.1,,,,,,,ANKZ1_RAT,Rattus norvegicus (Rat),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mitochondria-associated ubiquitin-dependent protein catabolic process [GO:0072671]; nucleus-associated proteasomal ubiquitin-dependent protein catabolic process [GO:0071630] comp132285_c0_seq1,2075,36.9157,0.65229523,6096,16695,,5.00E-39,Q07352,"Zinc finger protein 36, C3H1 type-like 1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (Protein TIS11B)","Zinc finger protein 36, C3H1 type-like 1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (Protein TIS11B)",GO:0003677; GO:0033077; GO:0005829; GO:0010467; GO:0003729; GO:0016071; GO:0046872; GO:0000288; GO:0005634; GO:0043488; GO:0006417; GO:0003700; GO:0001570,"DNA binding; T cell differentiation in thymus; cytosol; gene expression; mRNA binding; mRNA metabolic process; metal ion binding; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; nucleus; regulation of mRNA stability; regulation of translation; sequence-specific DNA binding transcription factor activity; vasculogenesis",PF04553;PF00642;,2.00E-28,CHOYP_BRAFLDRAFT_99019.8.8,4.00E-92,ruditapes_c16191,,,,,TISB_HUMAN,Homo sapiens (Human),"3'-UTR-mediated mRNA destabilization [GO:0061158]; apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to raffinose [GO:0097403]; cellular response to salt stress [GO:0071472]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; chorio-allantoic fusion [GO:0060710]; ERK1 and ERK2 cascade [GO:0070371]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mesendoderm development [GO:0048382]; mRNA transport [GO:0051028]; multicellular organism growth [GO:0035264]; negative regulation of erythrocyte differentiation [GO:0045647]; neural tube development [GO:0021915]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA catabolic process, deadenylation-independent decay [GO:0031086]; p38MAPK cascade [GO:0038066]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; proepicardium development [GO:0003342]; protein kinase B signaling [GO:0043491]; regulation of gene expression [GO:0010468]; regulation of keratinocyte apoptotic process [GO:1902172]; regulation of keratinocyte differentiation [GO:0045616]; regulation of keratinocyte proliferation [GO:0010837]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA stability [GO:0043488]; regulation of myoblast differentiation [GO:0045661]; regulation of stem cell proliferation [GO:0072091]; response to wounding [GO:0009611]; spongiotrophoblast layer development [GO:0060712]; T cell differentiation in thymus [GO:0033077]; vasculogenesis [GO:0001570]" comp132286_c0_seq1,1454,34.8006,0.43286641,30,500,,9.00E-28,Q5RAU6,Protein kish-B (Transmembrane protein 167B),Protein kish-B (Transmembrane protein 167B),GO:0000139; GO:0016021,Golgi membrane; integral to membrane,PF06842;,2.00E-33,CHOYP_LOC753641.1.1,,,,,,,KISHB_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp132289_c1_seq1,608,44.2434,0.20300055,9,144,,6.00E-28,Q498K0,Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),GO:0005975; GO:0004336; GO:0006683; GO:0005764,carbohydrate metabolic process; galactosylceramidase activity; galactosylceramide catabolic process; lysosome,PF02057;,,,,,,,,,GALC_XENLA,Xenopus laevis (African clawed frog),carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683] comp132290_c1_seq3,1099,38.1256,0.75208595,3,22,,1.00E-07,Q3UFY8,Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),GO:0008168; GO:0000964; GO:0042645; GO:0005739; GO:0008033,methyltransferase activity; mitochondrial RNA 5'-end processing; mitochondrial nucleoid; mitochondrion; tRNA processing,PF01746;,,,,,,,,,MRRP1_MOUSE,Mus musculus (Mouse),mitochondrial RNA 5'-end processing [GO:0000964] comp132296_c1_seq1,578,40.4844,0.78426,73,35,,3.00E-23,Q3T0C9,Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Mitochondrial outer membrane protein 25),Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Mitochondrial outer membrane protein 25),GO:0006897; GO:0016021; GO:0005741; GO:0048471,endocytosis; integral to membrane; mitochondrial outer membrane; perinuclear region of cytoplasm,PF00595;,,,,,,,,,SYJ2B_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; regulation of Notch signaling pathway [GO:0008593] comp132297_c0_seq1,332,44.2771,0.84386731,18,48,,1.00E-05,P55205,Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (GC-G) (Kinase-like domain-containing soluble guanylyl cyclase) (ksGC),Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (GC-G) (Kinase-like domain-containing soluble guanylyl cyclase) (ksGC),GO:0005524; GO:0005525; GO:0005737; GO:0004383; GO:0016021; GO:0035556; GO:0005886; GO:0004672,ATP binding; GTP binding; cytoplasm; guanylate cyclase activity; integral to membrane; intracellular signal transduction; plasma membrane; protein kinase activity,PF01094;PF00211;PF07714;,,,,,,,,,GUC2G_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165] comp132297_c1_seq2,1077,43.3612,0.43905547,15,27,,1.00E-116,Q9NYL2,Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK),Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK),GO:0005524; GO:0000077; GO:0004709; GO:0007257; GO:0007050; GO:0008219; GO:0030154; GO:0008283; GO:0005737; GO:0007010; GO:0000287; GO:0005634; GO:0043065; GO:0009314,ATP binding; DNA damage checkpoint; MAP kinase kinase kinase activity; activation of JUN kinase activity; cell cycle arrest; cell death; cell differentiation; cell proliferation; cytoplasm; cytoskeleton organization; magnesium ion binding; nucleus; positive regulation of apoptotic process; response to radiation,PF07714;PF00536;,3.00E-92,CHOYP_MLTK.1.1,,,,,,,MLTK_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cell cycle checkpoint [GO:0000075]; cell death [GO:0008219]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; cytoskeleton organization [GO:0007010]; DNA damage checkpoint [GO:0000077]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; response to radiation [GO:0009314]; response to stress [GO:0006950] comp132297_c1_seq3,869,42.8078,0.4325073,0,0,,5.00E-75,Q9NYL2,Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK),Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK),GO:0005524; GO:0000077; GO:0004709; GO:0007257; GO:0007050; GO:0008219; GO:0030154; GO:0008283; GO:0005737; GO:0007010; GO:0000287; GO:0005634; GO:0043065; GO:0009314,ATP binding; DNA damage checkpoint; MAP kinase kinase kinase activity; activation of JUN kinase activity; cell cycle arrest; cell death; cell differentiation; cell proliferation; cytoplasm; cytoskeleton organization; magnesium ion binding; nucleus; positive regulation of apoptotic process; response to radiation,PF07714;PF00536;,,,,,,,,,MLTK_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cell cycle checkpoint [GO:0000075]; cell death [GO:0008219]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; cytoskeleton organization [GO:0007010]; DNA damage checkpoint [GO:0000077]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; response to radiation [GO:0009314]; response to stress [GO:0006950] comp132299_c0_seq1,550,44.5455,0.44274956,0,0,,2.00E-23,Q9Y4F1,"FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)","FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)",GO:0030676; GO:0030054; GO:0005856; GO:0005829; GO:0030425; GO:0048813; GO:0043197; GO:0031234; GO:0030175; GO:0010923; GO:0005543; GO:0035023; GO:0045202; GO:0007416,Rac guanyl-nucleotide exchange factor activity; cell junction; cytoskeleton; cytosol; dendrite; dendrite morphogenesis; dendritic spine; extrinsic to internal side of plasma membrane; filopodium; negative regulation of phosphatase activity; phospholipid binding; regulation of Rho protein signal transduction; synapse; synapse assembly,PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;,,,,,,,,,FARP1_HUMAN,Homo sapiens (Human),dendrite morphogenesis [GO:0048813]; negative regulation of phosphatase activity [GO:0010923]; regulation of Rho protein signal transduction [GO:0035023]; synapse assembly [GO:0007416] comp132299_c0_seq2,1440,43.6111,0.60025225,50,54,,5.00E-37,Q7Z6J6,FERM domain-containing protein 5,FERM domain-containing protein 5,GO:0005737; GO:0005856; GO:0019898; GO:0016021,cytoplasm; cytoskeleton; extrinsic to membrane; integral to membrane,PF08736;PF09380;PF00373;PF09379;,1.00E-55,CHOYP_ISCW_ISCW003928.1.1,4.00E-40,ruditapes_c20921,,,,,FRMD5_HUMAN,Homo sapiens (Human), comp132303_c0_seq1,1868,39.6681,0.45258235,34,38,,4.00E-28,Q4V8F4,Rab9 effector protein with kelch motifs,Rab9 effector protein with kelch motifs,GO:0010008; GO:0005886,endosome membrane; plasma membrane,PF01344;PF07646;,,,,,,,,,RABEK_RAT,Rattus norvegicus (Rat), comp132303_c0_seq2,1844,39.4252,0.4652257,6,44,,3.00E-28,Q4V8F4,Rab9 effector protein with kelch motifs,Rab9 effector protein with kelch motifs,GO:0010008; GO:0005886,endosome membrane; plasma membrane,PF01344;PF07646;,2.00E-85,CHOYP_LOC100376506.1.1,,,,,,,RABEK_RAT,Rattus norvegicus (Rat), comp132305_c0_seq1,1219,33.7982,0.40756942,648,4578,,3.00E-93,Q28CQ4,SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I),SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I),GO:0005524; GO:0019789; GO:0051301; GO:0007059; GO:0007067; GO:0005634; GO:0016925,ATP binding; SUMO ligase activity; cell division; chromosome segregation; mitosis; nucleus; protein sumoylation,PF00179;,3.00E-87,CHOYP_UBC9B.1.1,1.00E-58,ruditapes_c20719,,,,,UBC9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; protein sumoylation [GO:0016925] comp132305_c0_seq2,1133,33.7158,0.37475244,566,4089,,3.00E-87,Q95017,SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2 9) (Ubiquitin-protein ligase 9),SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2 9) (Ubiquitin-protein ligase 9),GO:0005524; GO:0019789; GO:0009952; GO:0009792; GO:0000122; GO:0002119; GO:0043282; GO:0016925; GO:0032880,ATP binding; SUMO ligase activity; anterior/posterior pattern specification; embryo development ending in birth or egg hatching; negative regulation of transcription from RNA polymerase II promoter; nematode larval development; pharyngeal muscle development; protein sumoylation; regulation of protein localization,PF00179;,,,1.00E-114,ruditapes2_c482,,,,,UBC9_CAEEL,Caenorhabditis elegans,anterior/posterior pattern specification [GO:0009952]; embryo development ending in birth or egg hatching [GO:0009792]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nematode larval development [GO:0002119]; pharyngeal muscle development [GO:0043282]; protein sumoylation [GO:0016925]; regulation of cellular protein localization [GO:1903827] comp132307_c0_seq1,1062,44.162,0.53091057,0,0,,8.00E-07,O35889,Afadin (Protein Af-6),Afadin (Protein Af-6),GO:0007155; GO:0005913; GO:0005829; GO:0007165,cell adhesion; cell-cell adherens junction; cytosol; signal transduction,PF01843;PF00498;PF00595;PF00788;,6.00E-13,CHOYP_KI16B.3.3,,,,,,,AFAD_RAT,Rattus norvegicus (Rat),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; signal transduction [GO:0007165] comp132307_c0_seq2,1545,44.2718,0.54171982,0,0,,5.00E-38,Q02241,Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),GO:0005524; GO:0019886; GO:0007596; GO:0097149; GO:0005813; GO:0000910; GO:0005829; GO:0045171; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018; GO:0030496; GO:0000022; GO:0005654; GO:0032467; GO:0051256,ATP binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; centralspindlin complex; centrosome; cytokinesis; cytosol; intercellular bridge; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement; midbody; mitotic spindle elongation; nucleoplasm; positive regulation of cytokinesis; spindle midzone assembly involved in mitosis,PF00225;PF16540;,,,,,,,,,KIF23_HUMAN,Homo sapiens (Human),"actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp132307_c0_seq3,2046,44.5748,0.56619593,37,16,,0,Q9EQW7,Kinesin-like protein KIF13A,Kinesin-like protein KIF13A,GO:0005524; GO:0000139; GO:0043001; GO:0035459; GO:0005813; GO:0000910; GO:0010008; GO:0008333; GO:0005871; GO:0032438; GO:0005874; GO:0003777; GO:0030496; GO:0072383; GO:0032588,ATP binding; Golgi membrane; Golgi to plasma membrane protein transport; cargo loading into vesicle; centrosome; cytokinesis; endosome membrane; endosome to lysosome transport; kinesin complex; melanosome organization; microtubule; microtubule motor activity; midbody; plus-end-directed vesicle transport along microtubule; trans-Golgi network membrane,PF12473;PF12423;PF00225;PF16183;,0,CHOYP_LOC100881280.1.1,,,,,,,KI13A_MOUSE,Mus musculus (Mouse),cargo loading into vesicle [GO:0035459]; cytokinesis [GO:0000910]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; plus-end-directed vesicle transport along microtubule [GO:0072383] comp132308_c0_seq1,1176,46.7687,0.62294953,0,0,,1.00E-28,Q12802,A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47),A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47),GO:0005089; GO:0097190; GO:0004691; GO:0005829; GO:0016020; GO:0046872; GO:0048011; GO:0005634; GO:0005543; GO:0043065; GO:0035023; GO:1900169; GO:0051056; GO:0004871; GO:0007264,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; cAMP-dependent protein kinase activity; cytosol; membrane; metal ion binding; neurotrophin TRK receptor signaling pathway; nucleus; phospholipid binding; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of glucocorticoid mediated signaling pathway; regulation of small GTPase mediated signal transduction; signal transducer activity; small GTPase mediated signal transduction,PF00169;PF00621;PF10522;,,,,,,,,,AKP13_HUMAN,Homo sapiens (Human),adrenergic receptor signaling pathway [GO:0071875]; adrenergic receptor signaling pathway involved in heart process [GO:0086023]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cardiac muscle hypertrophy [GO:0010611]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of protein kinase activity [GO:0045859]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] comp132308_c0_seq4,1109,44.6348,0.74294823,2,0,,,,,,,,,2.00E-18,CHOYP_AKP13.5.5,,,,,,,,, comp132312_c0_seq1,2140,38.5047,0.54892421,562,848,,6.00E-38,Q8VDF2,E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1),E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1),GO:0006281; GO:0007049; GO:0008283; GO:0000791; GO:0044729; GO:0000792; GO:0010390; GO:0010216; GO:0035064; GO:0000122; GO:0000790; GO:0016363; GO:0031493; GO:0051865; GO:0042787; GO:0005657; GO:0006351; GO:0004842; GO:0008270,"DNA repair; cell cycle; cell proliferation; euchromatin; hemi-methylated DNA-binding; heterochromatin; histone monoubiquitination; maintenance of DNA methylation; methylated histone residue binding; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; nuclear matrix; nucleosomal histone binding; protein autoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; replication fork; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00628;PF02182;PF12148;PF00240;,5.00E-68,CHOYP_LOC756912.2.2,,,,,,,UHRF1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; cell proliferation [GO:0008283]; DNA methylation on cytosine [GO:0032776]; DNA repair [GO:0006281]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of methylation-dependent chromatin silencing [GO:0090308]; response to peptide hormone [GO:0043434]; transcription, DNA-templated [GO:0006351]" comp132314_c0_seq1,1533,42.2701,0.36963515,3840,40649,,1.00E-167,P40925,"Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) (Diiodophenylpyruvate reductase) (EC 1.1.1.96)","Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) (Diiodophenylpyruvate reductase) (EC 1.1.1.96)",GO:0030060; GO:0051287; GO:0006734; GO:0044262; GO:0005813; GO:0005829; GO:0047860; GO:0006094; GO:0006108; GO:0004470; GO:0005739; GO:0006107; GO:0044281; GO:0006099,L-malate dehydrogenase activity; NAD binding; NADH metabolic process; cellular carbohydrate metabolic process; centrosome; cytosol; diiodophenylpyruvate reductase activity; gluconeogenesis; malate metabolic process; malic enzyme activity; mitochondrion; oxaloacetate metabolic process; small molecule metabolic process; tricarboxylic acid cycle,PF02866;PF00056;,3.00E-94,CHOYP_MDHC.1.1,7.00E-107,ruditapes_c452,,,,,MDHC_HUMAN,Homo sapiens (Human),gluconeogenesis [GO:0006094]; malate metabolic process [GO:0006108]; mitophagy in response to mitochondrial depolarization [GO:0098779]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; positive regulation of defense response to virus by host [GO:0002230]; tricarboxylic acid cycle [GO:0006099]; xenophagy [GO:0098792] comp132315_c1_seq3,1597,41.2649,0.43441026,0,6,,,,,,,,,8.00E-33,CHOYP_IPO7.1.1,,,,,,,,, comp132315_c2_seq2,1700,43.1176,0.3547288,11,290,,2.00E-08,Q9NTW7,"Zinc finger protein 64 homolog, isoforms 3 and 4 (Zfp-64) (Zinc finger protein 338)","Zinc finger protein 64 homolog, isoforms 3 and 4 (Zfp-64) (Zinc finger protein 338)",GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,6.00E-47,CHOYP_BRAFLDRAFT_66688.2.2,,,,,,,ZF64B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132317_c0_seq1,2343,39.0098,0.96706646,8086,37037,,3.00E-88,P08051,"Myosin regulatory light chain, smooth muscle","Myosin regulatory light chain, smooth muscle",GO:0005509; GO:0016459,calcium ion binding; myosin complex,PF13405;,6.00E-36,CHOYP_MLRA.2.3,3.00E-38,ruditapes2_c18,,,,,MLR_SPISA,Spisula sachalinensis (Sakhalin surf-clam) (Pseudocardium sachalinense), comp132319_c0_seq1,1464,41.9399,0.78325528,79,5,,3.00E-130,Q5RG45,Centrosomal protein of 135 kDa (Cep135),Centrosomal protein of 135 kDa (Cep135),GO:0005814; GO:0007099; GO:0010457,centriole; centriole replication; centriole-centriole cohesion,,1.00E-156,CHOYP_LOC576511.1.1,,,,,,,CP135_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099] comp132325_c1_seq1,1984,33.4173,0.45652346,462,4318,,6.00E-08,P18322,Profilin-P,Profilin-P,GO:0030036; GO:0005737; GO:0005856,actin cytoskeleton organization; cytoplasm; cytoskeleton,PF00235;,,,,,,,,,PROF2_PHYPO,Physarum polycephalum (Slime mold), comp132326_c0_seq1,931,45.435,0.44451562,33,89,,2.00E-116,Q86SQ9,Dehydrodolichyl diphosphate synthase (Dedol-PP synthase) (EC 2.5.1.-) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Epididymis tissue protein Li 189m),Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Epididymis tissue protein Li 189m),GO:0005789; GO:0006486; GO:0016765,"endoplasmic reticulum membrane; protein glycosylation; transferase activity, transferring alkyl or aryl (other than methyl) groups",PF01255;,4.00E-97,CHOYP_BRAFLDRAFT_281462.1.1,,,,,,,DHDDS_HUMAN,Homo sapiens (Human),dolichyl diphosphate biosynthetic process [GO:0006489]; protein glycosylation [GO:0006486] comp132329_c0_seq1,1314,43.6073,0.87375466,365,3835,,2.00E-86,Q5E968,Cathepsin K (EC 3.4.22.38),Cathepsin K (EC 3.4.22.38),GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08246;PF00112;,4.00E-16,CHOYP_LOC659226.3.3,3.00E-29,ruditapes_c1257,,,,,CATK_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp132330_c3_seq1,740,44.7297,0.32595367,25,16,,4.00E-46,Q07DZ5,Cortactin-binding protein 2 (CortBP2),Cortactin-binding protein 2 (CortBP2),GO:0005938; GO:0043197,cell cortex; dendritic spine,PF12796;PF09727;,3.00E-21,CHOYP_CTTB2.1.2,,,,,,,CTTB2_ORNAN,Ornithorhynchus anatinus (Duckbill platypus), comp132330_c4_seq2,913,43.3735,0.27979625,5,0,,1.00E-21,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,,,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp132330_c4_seq4,831,43.4416,0.28153111,0,0,,8.00E-17,Q08E43,Ankyrin repeat and SOCS box protein 8 (ASB-8),Ankyrin repeat and SOCS box protein 8 (ASB-8),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB8_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp132337_c0_seq3,1095,42.1005,0.95441546,15,58,,8.00E-49,Q7Z449,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0008219; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0097267; GO:0006805,aromatase activity; cell death; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; omega-hydroxylase P450 pathway; xenobiotic metabolic process,PF00067;,,,,,,,,,CP2U1_HUMAN,Homo sapiens (Human),omega-hydroxylase P450 pathway [GO:0097267] comp132338_c0_seq1,1031,37.0514,0.53772161,553,3437,,5.00E-101,Q5RFQ0,rRNA-processing protein FCF1 homolog,rRNA-processing protein FCF1 homolog,GO:0005730; GO:0006364; GO:0032040,nucleolus; rRNA processing; small-subunit processome,PF04900;,5.00E-115,CHOYP_LOC100177727.1.1,2.00E-124,ruditapes_c767,,,,,FCF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),rRNA processing [GO:0006364] comp132340_c0_seq1,632,35.443,0.3626032,40,8,,2.00E-16,O95816,BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2),BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2),GO:0006457,protein folding,,,,,,,,,,BAG2_HUMAN,Homo sapiens (Human),protein folding [GO:0006457]; protein metabolic process [GO:0019538]; regulation of cellular response to heat [GO:1900034] comp132342_c0_seq2,2042,44.1724,0.45361482,14,7,,9.00E-14,O95429,BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains),BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains),GO:0071364; GO:0071356; GO:0005829; GO:0043066; GO:2001145; GO:0005634; GO:0005886; GO:0030838; GO:0045785; GO:0010763; GO:0033138; GO:0051897; GO:0051496; GO:0006457; GO:0072659; GO:0005057; GO:0097178,"cellular response to epidermal growth factor stimulus; cellular response to tumor necrosis factor; cytosol; negative regulation of apoptotic process; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; nucleus; plasma membrane; positive regulation of actin filament polymerization; positive regulation of cell adhesion; positive regulation of fibroblast migration; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of stress fiber assembly; protein folding; protein localization to plasma membrane; receptor signaling protein activity; ruffle assembly",PF02179;,,,,,,,,,BAG4_HUMAN,Homo sapiens (Human),"cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:2001145]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; regulation of cellular response to heat [GO:1900034]; ruffle assembly [GO:0097178]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp132342_c0_seq3,1985,44.534,0.48134294,10,0,,9.00E-14,O95429,BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains),BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains),GO:0071364; GO:0071356; GO:0005829; GO:0043066; GO:2001145; GO:0005634; GO:0005886; GO:0030838; GO:0045785; GO:0010763; GO:0033138; GO:0051897; GO:0051496; GO:0006457; GO:0072659; GO:0005057; GO:0097178,"cellular response to epidermal growth factor stimulus; cellular response to tumor necrosis factor; cytosol; negative regulation of apoptotic process; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; nucleus; plasma membrane; positive regulation of actin filament polymerization; positive regulation of cell adhesion; positive regulation of fibroblast migration; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of stress fiber assembly; protein folding; protein localization to plasma membrane; receptor signaling protein activity; ruffle assembly",PF02179;,,,1.00E-28,ruditapes_c16104,,,,,BAG4_HUMAN,Homo sapiens (Human),"cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:2001145]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; regulation of cellular response to heat [GO:1900034]; ruffle assembly [GO:0097178]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp132344_c0_seq1,604,45.1987,0.65582836,9,24,,4.00E-19,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132344_c0_seq2,1145,42.0087,0.52356392,31,102,,9.00E-41,Q4V8R6,Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),GO:0003677; GO:0051301; GO:0005737; GO:0016874; GO:0046872; GO:0007067; GO:0005654; GO:0016567; GO:0040008; GO:0006355; GO:0006351,"DNA binding; cell division; cytoplasm; ligase activity; metal ion binding; mitosis; nucleoplasm; protein ubiquitination; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,1.00E-27,CHOYP_LOC100694005.1.1,,,,,,,E4F1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp132347_c0_seq1,912,39.5833,0.79297819,522,2344,,3.00E-62,Q9NQT4,Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B),Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B),GO:0000175; GO:0045006; GO:0003723; GO:0005829; GO:0051607; GO:0043928; GO:0000178; GO:0005730; GO:0006364; GO:0035327,3'-5'-exoribonuclease activity; DNA deamination; RNA binding; cytosol; defense response to virus; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; exosome (RNase complex); nucleolus; rRNA processing; transcriptionally active chromatin,PF01138;PF03725;,5.00E-20,CHOYP_BRAFLDRAFT_124523.1.1,,,,,,,EXOS5_HUMAN,Homo sapiens (Human),"defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; regulation of mRNA stability [GO:0043488]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475]" comp132353_c0_seq1,1483,42.9535,0.431214,65,247,,5.00E-32,Q5EAW4,Protein MCM10 homolog,Protein MCM10 homolog,GO:0003677; GO:0006260; GO:0046872; GO:0005634,DNA binding; DNA replication; metal ion binding; nucleus,PF09332;PF09329;,,,,,,,,,MCM10_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260] comp132358_c0_seq1,1199,42.7023,0.29341667,0,0,,1.00E-24,P32018,Collagen alpha-1(XIV) chain (Undulin),Collagen alpha-1(XIV) chain (Undulin),GO:0007155; GO:0005581,cell adhesion; collagen,PF01391;PF00041;PF00092;,,,,,,,,,COEA1_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155] comp132358_c0_seq2,2113,40.0852,0.34181952,117,561,,2.00E-22,Q02388,Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen),Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen),GO:0005604; GO:0007155; GO:0030574; GO:0005590; GO:0005788; GO:0008544; GO:0022617; GO:0004867,basement membrane; cell adhesion; collagen catabolic process; collagen type VII; endoplasmic reticulum lumen; epidermis development; extracellular matrix disassembly; serine-type endopeptidase inhibitor activity,PF01391;PF00041;PF00014;PF00092;,,,,,,,,,CO7A1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; COPII vesicle coating [GO:0048208]; endodermal cell differentiation [GO:0035987]; epidermis development [GO:0008544]; ER to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix organization [GO:0030198] comp132359_c1_seq1,1872,42.2009,0.49289488,0,0,,2.00E-81,A2CE44,Zinc finger X-linked protein ZXDA/ZXDB,Zinc finger X-linked protein ZXDB,GO:0070742; GO:0046872; GO:0003676; GO:0005634; GO:0045893; GO:0003700; GO:0006351,"C2H2 zinc finger domain binding; metal ion binding; nucleic acid binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13912;,5.00E-36,CHOYP_LOC100366838.1.1,,,,,,,ZXDAB_MOUSE,Mus musculus (Mouse),"positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp132359_c1_seq2,1911,39.8744,0.5538514,0,0,,1.00E-26,Q8BKX7,Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1),Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN410_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132359_c1_seq3,1017,43.2645,0.56988299,0,0,,1.00E-24,Q98T94,Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein),Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein),GO:0003677; GO:0030154; GO:0005737; GO:0046872; GO:0045892; GO:0007399; GO:0016607; GO:0045893; GO:0006351,"DNA binding; cell differentiation; cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; nervous system development; nuclear speck; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,GLIS2_XENLA,Xenopus laevis (African clawed frog),"cell differentiation [GO:0030154]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp132359_c1_seq4,2766,40.2025,0.50160732,0,0,,2.00E-81,P98169,Zinc finger X-linked protein ZXDB,Zinc finger X-linked protein ZXDB,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZXDB_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132360_c0_seq1,1835,39.9455,0.48881804,163,828,,2.00E-171,Q9D864,Actin-related protein 6 (mArp6),Actin-related protein 6 (mArp6),GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF00022;,4.00E-139,CHOYP_ARP6.1.1,3.00E-11,ruditapes_c15823,,,,,ARP6_MOUSE,Mus musculus (Mouse),chromatin remodeling [GO:0006338] comp132361_c0_seq1,1894,40.7075,0.48846846,96,123,,4.00E-150,Q96DX4,RING finger and SPRY domain-containing protein 1,RING finger and SPRY domain-containing protein 1,GO:0005576; GO:0008270,extracellular region; zinc ion binding,PF00622;,2.00E-97,CHOYP_LOC100881468.1.1,,,,,,,RSPRY_HUMAN,Homo sapiens (Human), comp132366_c0_seq1,1574,42.8844,1.09600488,429,1196,,,,,,,,,5.00E-35,CHOYP_LOC100640001.1.2,4.00E-97,ruditapes_c24293,,,,,,, comp132368_c0_seq1,1801,42.1988,0.53030096,161,314,,0,Q8TBG4,Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1),Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1),GO:0008453; GO:0006520; GO:0050459; GO:0005739; GO:0030170,alanine-glyoxylate transaminase activity; cellular amino acid metabolic process; ethanolamine-phosphate phospho-lyase activity; mitochondrion; pyridoxal phosphate binding,PF00202;,4.00E-50,CHOYP_LOC100879339.1.1,5.00E-21,ruditapes_c8203,,,,,AT2L1_HUMAN,Homo sapiens (Human),phosphatidylethanolamine biosynthetic process [GO:0006646] comp132370_c0_seq3,1062,38.8889,0.97316988,0,0,,4.00E-46,Q6ICH7,Aspartate beta-hydroxylase domain-containing protein 2 (EC 1.14.11.-),Aspartate beta-hydroxylase domain-containing protein 2 (EC 1.14.11.-),GO:0051213; GO:0016021; GO:0018193,dioxygenase activity; integral to membrane; peptidyl-amino acid modification,PF05118;,,,,,,,,,ASPH2_HUMAN,Homo sapiens (Human),peptidyl-amino acid modification [GO:0018193] comp132371_c0_seq1,2815,46.1812,0.45425933,62,178,,1.00E-90,Q6NRD3,E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (xPOSH) (SH3 domain-containing RING finger protein 1),E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (xPOSH) (SH3 domain-containing RING finger protein 1),GO:0005794; GO:0030027; GO:0016874; GO:0048471; GO:0016567; GO:0008270,Golgi apparatus; lamellipodium; ligase activity; perinuclear region of cytoplasm; protein ubiquitination; zinc ion binding,PF00018;PF14604;PF00097;,4.00E-33,CHOYP_LOC101155413.1.1,,,,,,,SH3R1_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of JNK cascade [GO:0046328] comp132371_c0_seq2,1053,44.0646,0.47019504,0,9,,1.00E-08,Q9Y5K6,CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains),CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains),GO:0051301; GO:0005737; GO:0031941; GO:0007067; GO:0005730; GO:0005886; GO:0006461; GO:0001726; GO:0007165; GO:0005200; GO:0006930,"cell division; cytoplasm; filamentous actin; mitosis; nucleolus; plasma membrane; protein complex assembly; ruffle; signal transduction; structural constituent of cytoskeleton; substrate-dependent cell migration, cell extension",PF00018;PF14604;,,,,,,,,,CD2AP_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transforming growth factor beta1 production [GO:0032911]; positive regulation of protein localization to nucleus [GO:1900182]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of receptor-mediated endocytosis [GO:0048259]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; substrate-dependent cell migration, cell extension [GO:0006930]; vesicle organization [GO:0016050]" comp132372_c0_seq1,996,43.7751,0.46203291,14,167,,8.00E-121,Q7SIG4,Diisopropyl-fluorophosphatase (DFPase) (EC 3.1.8.2),Diisopropyl-fluorophosphatase (DFPase) (EC 3.1.8.2),GO:0005509; GO:0047862,calcium ion binding; diisopropyl-fluorophosphatase activity,PF08450;,6.00E-38,CHOYP_DFPA.1.1,,,,,,,DFPA_LOLVU,Loligo vulgaris (Common European squid), comp132379_c0_seq1,1189,44.2389,0.51976451,87,87,,1.00E-40,A6NK53,Zinc finger protein 233,Zinc finger protein 233,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN233_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132379_c1_seq2,1010,47.0297,0.39509062,5,15,,2.00E-12,Q99612,Krueppel-like factor 6 (B-cell-derived protein 1) (Core promoter element-binding protein) (GC-rich sites-binding factor GBF) (Proto-oncogene BCD1) (Suppressor of tumorigenicity 12 protein) (Transcription factor Zf9),Krueppel-like factor 6 (B-cell-derived protein 1) (Core promoter element-binding protein) (GC-rich sites-binding factor GBF) (Proto-oncogene BCD1) (Suppressor of tumorigenicity 12 protein) (Transcription factor Zf9),GO:0030183; GO:0003677; GO:0019221; GO:0005737; GO:0046872; GO:0005634; GO:0045893; GO:0006351,"B cell differentiation; DNA binding; cytokine-mediated signaling pathway; cytoplasm; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,KLF6_HUMAN,Homo sapiens (Human),"B cell differentiation [GO:0030183]; cellular response to cycloheximide [GO:0071409]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide [GO:1901653]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]" comp132380_c0_seq3,1074,41.527,0.61569355,0,0,,1.00E-20,Q9NA13,"Inositol 1,4,5-trisphosphate receptor-like protein A","Inositol 1,4,5-trisphosphate receptor-like protein A",GO:0048102; GO:0030244; GO:0034670; GO:0005783; GO:0005789; GO:0005220; GO:0016021; GO:0051209,"autophagic cell death; cellulose biosynthetic process; chemotaxis to arachidonic acid; endoplasmic reticulum; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; release of sequestered calcium ion into cytosol",PF08454;PF01365;,8.00E-18,CHOYP_TRIADDRAFT_55241.1.1,,,,,,,IPLA_DICDI,Dictyostelium discoideum (Slime mold),aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209] comp132380_c0_seq4,1655,43.0211,0.54523135,0,0,,3.00E-29,Q9Z329,"Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)",GO:0005938; GO:0071320; GO:0071361; GO:0005220; GO:0016021; GO:0035091; GO:0005886; GO:0001666; GO:0016529; GO:0033017,"cell cortex; cellular response to cAMP; cellular response to ethanol; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; phosphatidylinositol binding; plasma membrane; response to hypoxia; sarcoplasmic reticulum; sarcoplasmic reticulum membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,0,CHOYP_LOC100375107.4.4,,,,,,,ITPR2_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; response to hypoxia [GO:0001666] comp132380_c0_seq6,1703,43.2179,0.55002834,0,0,,3.00E-32,Q9TU34,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0035091; GO:0051209; GO:0030658,"endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; phosphatidylinositol binding; release of sequestered calcium ion into cytosol; transport vesicle membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,2.00E-180,CHOYP_LOC100375107.1.4,,,,,,,ITPR1_BOVIN,Bos taurus (Bovine),intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209] comp132380_c0_seq7,1683,42.4242,0.55257765,0,0,,,,,,,,,3.00E-159,CHOYP_LOC100375107.2.4,,,,,,,,, comp132380_c0_seq8,1122,41.8895,0.61948416,0,0,,2.00E-22,Q9NA13,"Inositol 1,4,5-trisphosphate receptor-like protein A","Inositol 1,4,5-trisphosphate receptor-like protein A",GO:0048102; GO:0030244; GO:0034670; GO:0005783; GO:0005789; GO:0005220; GO:0016021; GO:0051209,"autophagic cell death; cellulose biosynthetic process; chemotaxis to arachidonic acid; endoplasmic reticulum; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; release of sequestered calcium ion into cytosol",PF08454;PF01365;,2.00E-115,CHOYP_LOC100375107.4.4,,,,,,,IPLA_DICDI,Dictyostelium discoideum (Slime mold),aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209] comp132380_c1_seq10,678,42.0354,0.40813553,6,0,,8.00E-06,Q8WSR4,"Inositol 1,4,5-trisphosphate receptor (ApIP3R)","Inositol 1,4,5-trisphosphate receptor (ApIP3R)",GO:0005789; GO:0005220; GO:0048016; GO:0016021; GO:0007275; GO:0007338,"endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; inositol phosphate-mediated signaling; integral to membrane; multicellular organismal development; single fertilization",PF08709;PF00520;PF02815;PF08454;PF01365;,,,,,,,,,ITPR_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),multicellular organism development [GO:0007275]; single fertilization [GO:0007338] comp132380_c1_seq11,1346,42.8678,0.62338361,7,0,,6.00E-06,Q9TU34,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0035091; GO:0051209; GO:0030658,"endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; phosphatidylinositol binding; release of sequestered calcium ion into cytosol; transport vesicle membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,1.00E-23,CHOYP_TRIADDRAFT_55241.1.1,,,,,,,ITPR1_BOVIN,Bos taurus (Bovine),intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209] comp132380_c1_seq12,1385,43.8989,0.51132839,88,55,,3.00E-08,Q8WN95,"Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)",GO:0060402; GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0030658,"calcium ion transport into cytosol; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; transport vesicle membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,,,,,,,,,ITPR3_BOVIN,Bos taurus (Bovine),calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402] comp132380_c1_seq13,584,43.1507,0.41115704,7,8,,2.00E-07,Q9NA13,"Inositol 1,4,5-trisphosphate receptor-like protein A","Inositol 1,4,5-trisphosphate receptor-like protein A",GO:0048102; GO:0030244; GO:0034670; GO:0005783; GO:0005789; GO:0005220; GO:0016021; GO:0051209,"autophagic cell death; cellulose biosynthetic process; chemotaxis to arachidonic acid; endoplasmic reticulum; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; release of sequestered calcium ion into cytosol",PF08454;PF01365;,,,,,,,,,IPLA_DICDI,Dictyostelium discoideum (Slime mold),aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209] comp132380_c1_seq4,2311,44.8723,0.49718564,0,0,,,,,,,,,1.00E-75,CHOYP_LOC100375107.4.4,,,,,,,,, comp132380_c1_seq5,860,39.3023,0.75460225,0,0,,,,,,,,,7.00E-24,CHOYP_TRIADDRAFT_55241.1.1,,,,,,,,, comp132380_c1_seq9,1409,44.9255,0.48654269,0,5,,5.00E-07,Q9Z329,"Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)",GO:0005938; GO:0071320; GO:0071361; GO:0005220; GO:0016021; GO:0035091; GO:0005886; GO:0001666; GO:0016529; GO:0033017,"cell cortex; cellular response to cAMP; cellular response to ethanol; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; phosphatidylinositol binding; plasma membrane; response to hypoxia; sarcoplasmic reticulum; sarcoplasmic reticulum membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,5.00E-47,CHOYP_LOC100375107.2.4,,,,,,,ITPR2_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; response to hypoxia [GO:0001666] comp132384_c0_seq2,634,36.9085,0.64947561,0,5,,2.00E-06,P0CY12,Putative mating-type protein A2 (MATa2 protein),Putative mating-type protein A2 (MATa2 protein),GO:0005634; GO:0043565; GO:0003700,nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;,,,,,,,,,MATA2_YEASX,Saccharomyces cerevisiae (Baker's yeast), comp132387_c0_seq4,834,42.5659,0.84863236,30,0,,1.00E-28,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp132389_c0_seq1,1150,38.6957,0.56230959,110,154,,1.00E-81,Q8BGF6,ELMO domain-containing protein 2,ELMO domain-containing protein 2,GO:0005096; GO:0005856; GO:0006909; GO:0050688,GTPase activator activity; cytoskeleton; phagocytosis; regulation of defense response to virus,PF04727;,,,9.00E-60,ruditapes_c18906,,,,,ELMD2_MOUSE,Mus musculus (Mouse),regulation of defense response to virus [GO:0050688] comp132393_c2_seq1,1970,43.7563,0.68174171,46,13,,0,P84025,Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3),Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3),GO:0071141; GO:0007183; GO:0042110; GO:0097296; GO:0007050; GO:0045216; GO:0031490; GO:0000987; GO:0005737; GO:0019049; GO:0097191; GO:0006955; GO:0043066; GO:0030308; GO:0008285; GO:0050728; GO:0045930; GO:0033689; GO:0042177; GO:0001933; GO:0000122; GO:0061045; GO:0038092; GO:0005637; GO:0005634; GO:0001649; GO:0010694; GO:0030501; GO:0090263; GO:0035413; GO:0030335; GO:0032332; GO:0010718; GO:0051894; GO:1901313; GO:0032731; GO:0050927; GO:0051496; GO:0042993; GO:0045944; GO:0032916; GO:0000988; GO:0050821; GO:0043235; GO:0050776; GO:0032909; GO:0001666; GO:0003700; GO:0023019; GO:0008134; GO:0005667; GO:0006351; GO:0060290; GO:0007179; GO:0030618; GO:0006810; GO:0001657; GO:0008270,"SMAD protein complex; SMAD protein complex assembly; T cell activation; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; cell cycle arrest; cell-cell junction organization; chromatin DNA binding; core promoter proximal region sequence-specific DNA binding; cytoplasm; evasion or tolerance of host defenses by virus; extrinsic apoptotic signaling pathway; immune response; negative regulation of apoptotic process; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of inflammatory response; negative regulation of mitotic cell cycle; negative regulation of osteoblast proliferation; negative regulation of protein catabolic process; negative regulation of protein phosphorylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of wound healing; nodal signaling pathway; nuclear inner membrane; nucleus; osteoblast differentiation; positive regulation of alkaline phosphatase activity; positive regulation of bone mineralization; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of catenin import into nucleus; positive regulation of cell migration; positive regulation of chondrocyte differentiation; positive regulation of epithelial to mesenchymal transition; positive regulation of focal adhesion assembly; positive regulation of gene expression involved in extracellular matrix organization; positive regulation of interleukin-1 beta production; positive regulation of positive chemotaxis; positive regulation of stress fiber assembly; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta3 production; protein binding transcription factor activity; protein stabilization; receptor complex; regulation of immune response; regulation of transforming growth factor beta2 production; response to hypoxia; sequence-specific DNA binding transcription factor activity; signal transduction involved in regulation of gene expression; transcription factor binding; transcription factor complex; transcription, DNA-dependent; transdifferentiation; transforming growth factor beta receptor signaling pathway; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; transport; ureteric bud development; zinc ion binding",PF03165;PF03166;,0,CHOYP_SMAD3.1.1,,,,,,,SMAD3_RAT,Rattus norvegicus (Rat),"activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; canonical Wnt signaling pathway [GO:0060070]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta3 production [GO:0032916]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transcription, DNA-templated [GO:0006351]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transport [GO:0006810]; ureteric bud development [GO:0001657]" comp132393_c2_seq2,1048,39.9809,0.58521671,3,0,,,,,,,,,4.00E-60,CHOYP_SMAD3.1.1,,,,,,,,, comp132398_c0_seq1,1248,39.1827,0.64359368,53,192,,1.00E-15,P91119,"Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)","Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)",GO:0004114; GO:0008152; GO:0046872; GO:0007165,"3',5'-cyclic-nucleotide phosphodiesterase activity; metabolic process; metal ion binding; signal transduction",PF01590;PF00233;,2.00E-25,CHOYP_TRIADDRAFT_21752.1.1,,,,,,,PDE5_CAEEL,Caenorhabditis elegans,chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP biosynthetic process [GO:0030827]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542] comp132404_c2_seq1,882,41.7234,0.50208055,4,196,,2.00E-106,A7S1L6,GDP-fucose transporter 1 (Solute carrier family 35 member C1 homolog),GDP-fucose transporter 1 (Solute carrier family 35 member C1 homolog),GO:0000139; GO:0008643; GO:0016021,Golgi membrane; carbohydrate transport; integral to membrane,PF03151;,5.00E-70,CHOYP_BRAFLDRAFT_118197.1.1,,,,,,,FUCT1_NEMVE,Nematostella vectensis (Starlet sea anemone),carbohydrate transport [GO:0008643] comp132406_c0_seq1,1597,40.0125,1.05199798,403,3817,,4.00E-25,P10621,Isopenicillin N synthase (IPNS) (EC 1.21.3.1),Isopenicillin N synthase (IPNS) (EC 1.21.3.1),GO:0031418; GO:0017000; GO:0005506; GO:0016216; GO:0016706,"L-ascorbic acid binding; antibiotic biosynthetic process; iron ion binding; isopenicillin-N synthase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF03171;PF14226;,8.00E-39,CHOYP_PMAA_001770.1.1,1.00E-14,ruditapes_c27218,,,,,IPNS_STRC2,Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602),antibiotic biosynthetic process [GO:0017000] comp132407_c0_seq1,1297,39.8612,0.43464257,50,296,,4.00E-72,Q5PQ50,"Nucleoside diphosphate-linked moiety X motif 19, mitochondrial (Nudix motif 19) (EC 3.6.1.-)",Nucleoside diphosphate-linked moiety X motif 19 (Nudix motif 19) (EC 3.6.1.-),GO:0016787; GO:0046872; GO:0005739; GO:0005777,hydrolase activity; metal ion binding; mitochondrion; peroxisome,,,,,,,,,,NUD19_XENLA,Xenopus laevis (African clawed frog), comp132408_c0_seq1,1238,37.8029,0.46914078,101,823,,6.00E-50,Q9BSV6,tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34),tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34),GO:0006397; GO:0003676; GO:0090305; GO:0005730; GO:0000213; GO:0000214; GO:0000379,mRNA processing; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleolus; tRNA-intron endonuclease activity; tRNA-intron endonuclease complex; tRNA-type intron splice site recognition and cleavage,PF01974;,3.00E-17,CHOYP_BRAFLDRAFT_239658.1.1,,,,,,,SEN34_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379]" comp132409_c0_seq1,1182,42.555,0.31515174,35,31,,7.00E-86,O02776,Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143),Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143),GO:0005975; GO:0005634; GO:0004649,carbohydrate metabolic process; nucleus; poly(ADP-ribose) glycohydrolase activity,PF05028;,2.00E-38,CHOYP_PARG.1.1,,,,,,,PARG_BOVIN,Bos taurus (Bovine),carbohydrate metabolic process [GO:0005975] comp132411_c0_seq1,991,41.6751,0.58309097,34,14,,6.00E-99,P54277,PMS1 protein homolog 1 (DNA mismatch repair protein PMS1),PMS1 protein homolog 1 (DNA mismatch repair protein PMS1),GO:0005524; GO:0016887; GO:0032389; GO:0032407; GO:0006298; GO:0030983; GO:0007131; GO:0003697,ATP binding; ATPase activity; MutLalpha complex; MutSalpha complex binding; mismatch repair; mismatched DNA binding; reciprocal meiotic recombination; single-stranded DNA binding,PF01119;PF00505;,,,,,,,,,PMS1_HUMAN,Homo sapiens (Human),mismatch repair [GO:0006298] comp132412_c0_seq1,1766,39.7508,0.55539858,255,93,,1.00E-40,P79145,cAMP-responsive element modulator,cAMP-responsive element modulator,GO:0006687; GO:0005634; GO:0045944; GO:0043565; GO:0003700; GO:0007283; GO:0005667; GO:0006351,"glycosphingolipid metabolic process; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; spermatogenesis; transcription factor complex; transcription, DNA-dependent",PF00170;PF02173;,2.00E-72,CHOYP_CREM.1.1,,,,,,,CREM_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),"circadian regulation of gene expression [GO:0032922]; glycosphingolipid metabolic process [GO:0006687]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cAMP [GO:0051591]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp132423_c0_seq1,949,41.412,0.62737813,27,73,,2.00E-45,Q3U0M1,Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein),Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein),GO:0005794; GO:0030154; GO:0005783,Golgi apparatus; cell differentiation; endoplasmic reticulum,PF08626;,1.00E-27,CHOYP_TRAPPC9.1.1,,,,,,,TPPC9_MOUSE,Mus musculus (Mouse),cerebral cortex development [GO:0021987]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092] comp132426_c0_seq1,864,37.5,0.33040533,323,1835,,3.00E-39,Q9NX08,COMM domain-containing protein 8,COMM domain-containing protein 8,,,PF07258;,,,,,,,,,COMD8_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132428_c0_seq2,676,39.645,0.22748706,24,126,,2.00E-47,Q2M2T6,Protein Asterix (Protein WDR83OS homolog),Protein Asterix (Protein WDR83OS homolog),GO:0016021,integral to membrane,PF03669;,1.00E-75,CHOYP_ASTER.1.4,1.00E-79,ruditapes_c16832,,,,,ASTER_BOVIN,Bos taurus (Bovine), comp132442_c1_seq1,1327,39.1861,0.5739072,12,34,,2.00E-09,Q6GQ66,FAST kinase domain-containing protein 1,"FAST kinase domain-containing protein 1, mitochondrial",GO:0045333; GO:0005739; GO:0004672; GO:0006468,cellular respiration; mitochondrion; protein kinase activity; protein phosphorylation,PF06743;PF08368;PF08373;,,,,,,,,,FAKD1_XENLA,Xenopus laevis (African clawed frog),cellular respiration [GO:0045333] comp132442_c1_seq2,1303,38.987,0.56959847,6,15,,1.00E-10,Q28DE0,FAST kinase domain-containing protein 1,"FAST kinase domain-containing protein 1, mitochondrial",GO:0045333; GO:0005739; GO:0004672; GO:0006468,cellular respiration; mitochondrion; protein kinase activity; protein phosphorylation,PF06743;PF08368;PF08373;,,,,,,,,,FAKD1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular respiration [GO:0045333] comp132445_c0_seq1,903,46.1794,0.50444145,27,43,,1.00E-93,Q9CXF0,Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase),Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase),GO:0097053; GO:0009435; GO:0043420; GO:0005829; GO:0030429; GO:0005739; GO:0005634; GO:0030170; GO:0019805; GO:0034341; GO:0034516; GO:0006569,L-kynurenine catabolic process; NAD biosynthetic process; anthranilate metabolic process; cytosol; kynureninase activity; mitochondrion; nucleus; pyridoxal phosphate binding; quinolinate biosynthetic process; response to interferon-gamma; response to vitamin B6; tryptophan catabolic process,PF00266;,,,,,,,,,KYNU_MOUSE,Mus musculus (Mouse),'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; response to interferon-gamma [GO:0034341]; response to vitamin B6 [GO:0034516]; tryptophan catabolic process [GO:0006569] comp132445_c2_seq1,635,42.3622,0.57110928,25,41,,2.00E-58,Q18026,Kynureninase (EC 3.7.1.3) (Abnormal fluorescence under UV illumination) (L-kynurenine hydrolase),Kynureninase (EC 3.7.1.3) (Abnormal fluorescence under UV illumination) (L-kynurenine hydrolase),GO:0097053; GO:0009435; GO:0005737; GO:0030429; GO:0030170; GO:0006569,L-kynurenine catabolic process; NAD biosynthetic process; cytoplasm; kynureninase activity; pyridoxal phosphate binding; tryptophan catabolic process,PF00266;,3.00E-59,CHOYP_LOC100485536.1.1,,,,,,,KYNU_CAEEL,Caenorhabditis elegans,'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569] comp132453_c2_seq1,1515,39.934,0.5348978,77,167,,6.00E-65,Q6NZW0,Coiled-coil domain-containing protein 102A,Coiled-coil domain-containing protein 102A,,,PF01576;,7.00E-27,CHOYP_C102A.1.1,,,,,,,C102A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp132454_c0_seq2,2070,37.2464,0.75391354,12,90,,2.00E-77,Q29496,Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24),Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,,,,,,,,,CP3AO_SHEEP,Ovis aries (Sheep), comp132455_c0_seq2,1346,41.679,0.25715936,0,15,,8.00E-15,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132455_c0_seq3,1132,45.318,0.2414971,0,8,,1.00E-15,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132456_c0_seq1,306,41.8301,0.5310163,8,148,,3.00E-07,Q94KK7,Syntaxin-52 (AtSYP52),Syntaxin-52 (AtSYP52),GO:0005794; GO:0005484; GO:0010008; GO:0016021; GO:0006886; GO:0031902; GO:0005773; GO:0016192,Golgi apparatus; SNAP receptor activity; endosome membrane; integral to membrane; intracellular protein transport; late endosome membrane; vacuole; vesicle-mediated transport,PF05739;,9.00E-30,CHOYP_LOC100372200.1.1,,,,,,,SYP52_ARATH,Arabidopsis thaliana (Mouse-ear cress),intracellular protein transport [GO:0006886]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] comp132456_c0_seq2,412,42.7184,0.43116527,49,232,,4.00E-22,Q3T075,Syntaxin-8,Syntaxin-8,GO:0005484; GO:0031201; GO:0016021; GO:0006886; GO:0006906,SNAP receptor activity; SNARE complex; integral to membrane; intracellular protein transport; vesicle fusion,PF05739;,,,,,,,,,STX8_BOVIN,Bos taurus (Bovine),early endosome to late endosome transport [GO:0045022]; intracellular protein transport [GO:0006886]; regulation of protein localization to plasma membrane [GO:1903076]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] comp132461_c0_seq1,1692,40.6619,0.7083624,1110,3986,,1.00E-121,Q8R323,Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38),Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38),GO:0016887; GO:0003677; GO:0006260; GO:0000166; GO:0005634; GO:0046683,ATPase activity; DNA binding; DNA replication; nucleotide binding; nucleus; response to organophosphorus,,1.00E-163,CHOYP_RFC3.1.1,8.00E-69,ruditapes_c17998,7.00E-153,AM858476.p.cg.6,8,,RFC3_MOUSE,Mus musculus (Mouse),DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]; response to organophosphorus [GO:0046683] comp132466_c0_seq7,1391,38.821,0.57862606,20,668,,,,,,,,,8.00E-32,CHOYP_PHF10.1.1,,,,,,,,, comp132471_c2_seq1,511,45.7926,0.60125001,3,15,,2.00E-47,Q8WWZ7,ATP-binding cassette sub-family A member 5,ATP-binding cassette sub-family A member 5,GO:0005524; GO:0006200; GO:0016887; GO:0000139; GO:0033344; GO:0034375; GO:0016021; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0010745; GO:0043691,ATP binding; ATP catabolic process; ATPase activity; Golgi membrane; cholesterol efflux; high-density lipoprotein particle remodeling; integral to membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; negative regulation of macrophage derived foam cell differentiation; reverse cholesterol transport,PF00005;,3.00E-45,CHOYP_TRIADDRAFT_53677.1.1,,,,,,,ABCA5_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; high-density lipoprotein particle remodeling [GO:0034375]; lipid transport [GO:0006869]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; reverse cholesterol transport [GO:0043691] comp132473_c0_seq2,1925,42.5974,0.4569563,276,2040,,0,Q5NVD0,U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4),U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4),GO:0008380; GO:0006397; GO:0016607; GO:0005681,RNA splicing; mRNA processing; nuclear speck; spliceosomal complex,PF08799;PF00400;,0,CHOYP_PRPF4.1.1,3.00E-56,ruditapes_c26461,,,,,PRP4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp132473_c1_seq1,696,41.3793,0.47242896,5,141,,7.00E-18,Q6NW85,E3 ubiquitin-protein ligase arih1l (EC 6.3.2.-),E3 ubiquitin-protein ligase arih1l (EC 6.3.2.-),GO:0005737; GO:0004842; GO:0008270,cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF01485;,,,,,,,,,ARI1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp132479_c0_seq1,689,39.7678,0.36169917,41,77,,3.00E-11,Q5SZL2,Centrosomal protein of 85 kDa-like (Serologically defined breast cancer antigen NY-BR-15),Centrosomal protein of 85 kDa-like (Serologically defined breast cancer antigen NY-BR-15),GO:0005813; GO:0005737,centrosome; cytoplasm,,,,,,,,,,CE85L_HUMAN,Homo sapiens (Human), comp132481_c0_seq1,951,32.9127,0.8951036,0,46,,,,,,,,,,,2.00E-15,ruditapes_c27413,,,,,,, comp132483_c0_seq2,1089,47.8421,0.69736705,72,5,,2.00E-58,Q6A4L1,Solute carrier family 12 member 8,Solute carrier family 12 member 8,GO:0016021; GO:0006813; GO:0015293,integral to membrane; potassium ion transport; symporter activity,PF00324;,6.00E-51,CHOYP_LOC592204.1.1,,,,,,,S12A8_XENLA,Xenopus laevis (African clawed frog),potassium ion transport [GO:0006813] comp132496_c0_seq1,860,37.2093,0.94117536,51,739,,,,,,,,,,,4.00E-12,ruditapes_c5444,,,,,,, comp132502_c0_seq2,517,41.3926,0.27167934,32,134,,,,,,,,,9.00E-20,CHOYP_LOC100718753.1.1,,,,,,,,, comp132502_c0_seq3,331,43.2024,0.66374056,5,25,,3.00E-34,Q9DCT6,Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa),Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa),GO:0003677; GO:0071339; GO:0016589; GO:0003682; GO:0016568,DNA binding; MLL1 complex; NURF complex; chromatin binding; chromatin modification,,4.00E-22,CHOYP_BAP18.1.1,,,,,,,BAP18_MOUSE,Mus musculus (Mouse),chromatin modification [GO:0016568] comp132510_c0_seq1,1939,41.1552,0.57667998,108,183,,1.00E-72,Q5ZID5,Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28),Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28),GO:0000077; GO:0006281; GO:0008283; GO:0042771; GO:0005654; GO:0016579; GO:0010212; GO:0004221; GO:0006511; GO:0004843,DNA damage checkpoint; DNA repair; cell proliferation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; nucleoplasm; protein deubiquitination; response to ionizing radiation; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,8.00E-21,CHOYP_UBP25.1.1,,,,,,,UBP28_CHICK,Gallus gallus (Chicken),cell proliferation [GO:0008283]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; protein deubiquitination [GO:0016579]; Ras protein signal transduction [GO:0007265]; regulation of protein stability [GO:0031647]; response to ionizing radiation [GO:0010212]; ubiquitin-dependent protein catabolic process [GO:0006511] comp132516_c0_seq1,942,35.0318,0.65111892,79,879,,5.00E-15,Q14657,EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2),EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2),,,PF09341;,8.00E-24,CHOYP_LOC100536597.1.1,,,,,,,LAGE3_HUMAN,Homo sapiens (Human),tRNA processing [GO:0008033] comp132517_c0_seq1,887,41.0372,0.58459587,87,375,,6.00E-50,Q8WXB1,Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A),Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A),GO:0005737; GO:0016279,cytoplasm; protein-lysine N-methyltransferase activity,PF10294;,,,,,,,,,MT21A_HUMAN,Homo sapiens (Human),peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479] comp132522_c0_seq1,1065,40.1878,0.48153628,121,558,,8.00E-98,Q9NTM9,Copper homeostasis protein cutC homolog,Copper homeostasis protein cutC homolog,GO:0016235; GO:0005507; GO:0055070; GO:0006825; GO:0005737; GO:0005730; GO:0051262,aggresome; copper ion binding; copper ion homeostasis; copper ion transport; cytoplasm; nucleolus; protein tetramerization,PF03932;,8.00E-18,CHOYP_CUTC.1.1,3.00E-15,ruditapes_c14114,,,,,CUTC_HUMAN,Homo sapiens (Human),copper ion homeostasis [GO:0055070]; copper ion transport [GO:0006825]; protein tetramerization [GO:0051262] comp132526_c0_seq1,1313,38.9947,0.94236722,291,21176,,,,,,,,,,,1.00E-15,ruditapes2_lrc3304,,,,,,, comp132527_c0_seq1,1374,38.2096,0.44169635,6,1,,7.00E-13,P61802,Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT),Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT),GO:0003677; GO:0006281; GO:0016787; GO:0046872; GO:0005730; GO:0005654,DNA binding; DNA repair; hydrolase activity; metal ion binding; nucleolus; nucleoplasm,PF16278;,,,,,,,,,APTX_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis),DNA repair [GO:0006281] comp132527_c0_seq2,1899,39.8104,0.42899086,0,0,,3.00E-137,Q9JLV6,Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)],Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)],GO:0005524; GO:0046404; GO:0006281; GO:0005634; GO:0098506; GO:0046403,ATP binding; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; DNA repair; nucleus; polynucleotide 3' dephosphorylation; polynucleotide 3'-phosphatase activity,PF08645;,3.00E-70,CHOYP_LOC100707367.1.1,,,,,,,PNKP_MOUSE,Mus musculus (Mouse),"dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; nucleotide phosphorylation [GO:0046939]; polynucleotide 3' dephosphorylation [GO:0098506]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]" comp132527_c0_seq4,1855,39.7844,0.41202643,0,9,,3.00E-137,Q9JLV6,Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)],Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)],GO:0005524; GO:0046404; GO:0006281; GO:0005634; GO:0098506; GO:0046403,ATP binding; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; DNA repair; nucleus; polynucleotide 3' dephosphorylation; polynucleotide 3'-phosphatase activity,PF08645;,3.00E-70,CHOYP_LOC100707367.1.1,,,,,,,PNKP_MOUSE,Mus musculus (Mouse),"dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; nucleotide phosphorylation [GO:0046939]; polynucleotide 3' dephosphorylation [GO:0098506]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]" comp132528_c1_seq12,955,34.6597,0.37011268,0,0,,2.00E-06,P62287,Abnormal spindle-like microcephaly-associated protein homolog,Abnormal spindle-like microcephaly-associated protein homolog,GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,,,,,,,,,ASPM_COLGU,Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp132528_c1_seq13,1243,39.6621,0.37810223,0,0,,4.00E-06,P62286,Abnormal spindle-like microcephaly-associated protein homolog,Abnormal spindle-like microcephaly-associated protein homolog,GO:0005737; GO:0048589; GO:0021873; GO:0051661; GO:0030496; GO:0007067; GO:0045769; GO:0045665; GO:0001764; GO:0005634; GO:0048477; GO:0090263; GO:0002052; GO:0007283; GO:0000922,cytoplasm; developmental growth; forebrain neuroblast division; maintenance of centrosome location; midbody; mitosis; negative regulation of asymmetric cell division; negative regulation of neuron differentiation; neuron migration; nucleus; oogenesis; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of neuroblast proliferation; spermatogenesis; spindle pole,PF15780;PF00307;PF00612;,,,,,,,,,ASPM_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cerebral cortex development [GO:0021987]; developmental growth [GO:0048589]; forebrain neuroblast division [GO:0021873]; maintenance of centrosome location [GO:0051661]; male gonad development [GO:0008584]; mitotic nuclear division [GO:0007067]; negative regulation of asymmetric cell division [GO:0045769]; negative regulation of neuron differentiation [GO:0045665]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; oogenesis [GO:0048477]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuroblast proliferation [GO:0002052]; regulation of meiotic cell cycle [GO:0051445]; spermatogenesis [GO:0007283]; spindle assembly involved in meiosis [GO:0090306]; spindle localization [GO:0051653] comp132528_c1_seq14,1752,38.1279,0.91437594,0,0,,1.00E-06,D3ZR10,Doublecortin domain-containing protein 2,Doublecortin domain-containing protein 2,GO:0035556; GO:0001764,intracellular signal transduction; neuron migration,PF03607;,,,,,,,,,DCDC2_RAT,Rattus norvegicus (Rat),cell projection organization [GO:0030030]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605] comp132528_c1_seq15,1460,36.7123,0.51870614,0,0,,2.00E-07,P62297,Abnormal spindle-like microcephaly-associated protein homolog (Fragment),Abnormal spindle-like microcephaly-associated protein homolog (Fragment),GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,,,,,,,,,ASPM_SHEEP,Ovis aries (Sheep),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp132528_c1_seq2,1821,38.5502,0.95021908,0,0,,3.00E-09,D3ZR10,Doublecortin domain-containing protein 2,Doublecortin domain-containing protein 2,GO:0035556; GO:0001764,intracellular signal transduction; neuron migration,PF03607;,,,,,,,,,DCDC2_RAT,Rattus norvegicus (Rat),cell projection organization [GO:0030030]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605] comp132528_c1_seq5,1392,40.6609,0.47823299,0,0,,1.00E-07,P62297,Abnormal spindle-like microcephaly-associated protein homolog (Fragment),Abnormal spindle-like microcephaly-associated protein homolog (Fragment),GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,,,,,,,,,ASPM_SHEEP,Ovis aries (Sheep),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp132528_c1_seq7,738,39.0244,0.11792575,0,0,,2.00E-08,P62297,Abnormal spindle-like microcephaly-associated protein homolog (Fragment),Abnormal spindle-like microcephaly-associated protein homolog (Fragment),GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,,,,,,,,,ASPM_SHEEP,Ovis aries (Sheep),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp132531_c0_seq1,1291,39.1944,0.84189497,98,123,,2.00E-84,Q5FVQ4,Malectin,Malectin,GO:0030246; GO:0005975; GO:0005783; GO:0005789; GO:0016021,carbohydrate binding; carbohydrate metabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane,PF11721;,7.00E-83,CHOYP_LOC100740246.1.1,,,,,,,MLEC_RAT,Rattus norvegicus (Rat),carbohydrate metabolic process [GO:0005975] comp132532_c0_seq2,1053,37.5119,0.35318106,85,296,,3.00E-45,P58467,SET domain-containing protein 4 (EC 2.1.1.-),SET domain-containing protein 4 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF09273;PF00856;,,,,,,,,,SETD4_MOUSE,Mus musculus (Mouse),peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; ribosome biogenesis [GO:0042254] comp132536_c1_seq1,4177,35.073,0.5469728,1026,2115,,2.00E-49,P07909,Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),GO:0036099; GO:0048027; GO:0033119; GO:0000166; GO:0005634; GO:0048477; GO:0005703; GO:0045727; GO:0000381; GO:0030529; GO:0043565,"female germ-line stem cell maintenance; mRNA 5'-UTR binding; negative regulation of RNA splicing; nucleotide binding; nucleus; oogenesis; polytene chromosome puff; positive regulation of translation; regulation of alternative mRNA splicing, via spliceosome; ribonucleoprotein complex; sequence-specific DNA binding",PF00076;,4.00E-16,CHOYP_ROA3.1.2,,,,,,,ROA1_DROME,Drosophila melanogaster (Fruit fly),"compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]" comp132536_c1_seq4,4213,35.3192,0.55905074,692,4591,,1.00E-49,P07909,Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A),GO:0036099; GO:0048027; GO:0033119; GO:0000166; GO:0005634; GO:0048477; GO:0005703; GO:0045727; GO:0000381; GO:0030529; GO:0043565,"female germ-line stem cell maintenance; mRNA 5'-UTR binding; negative regulation of RNA splicing; nucleotide binding; nucleus; oogenesis; polytene chromosome puff; positive regulation of translation; regulation of alternative mRNA splicing, via spliceosome; ribonucleoprotein complex; sequence-specific DNA binding",PF00076;,4.00E-16,CHOYP_ROA3.1.2,,,,,,,ROA1_DROME,Drosophila melanogaster (Fruit fly),"compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]" comp132540_c1_seq1,1096,36.7701,0.86650941,41,110,,1.00E-52,Q17QM8,Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48),Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48),GO:0017017; GO:0035335; GO:0004725; GO:0008138,MAP kinase tyrosine/serine/threonine phosphatase activity; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,,,,,,,,,DUS14_BOVIN,Bos taurus (Bovine),peptidyl-tyrosine dephosphorylation [GO:0035335] comp132541_c0_seq1,1129,43.7555,0.76858056,217,2732,,8.00E-77,Q5FW48,Putative L-aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain-containing protein),Putative L-aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain-containing protein),GO:0009435; GO:0050661; GO:0006742; GO:0033735,NAD biosynthetic process; NADP binding; NADP catabolic process; aspartate dehydrogenase activity,PF01958;PF03447;,,,5.00E-94,ruditapes_c7367,,,,,ASPD_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),NAD biosynthetic process [GO:0009435]; NADP catabolic process [GO:0006742] comp132545_c0_seq1,1255,38.4861,0.58967174,462,3249,,1.00E-31,Q9W6I0,Ubiquinol-cytochrome-c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein homolog) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog) (Zic3-binding protein),Ubiquinol-cytochrome-c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein homolog) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog) (Zic3-binding protein),,,PF03981;,,,,,,,,,UQCC_XENLA,Xenopus laevis (African clawed frog),mitochondrial respiratory chain complex III assembly [GO:0034551]; positive regulation of mitochondrial translation [GO:0070131] comp132546_c0_seq1,1075,42.0465,0.51136678,24,16,,4.00E-62,Q6GP15,Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25),Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11232;PF11244;PF11235;PF11265;,,,,,,,,,MED25_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132546_c0_seq2,1012,42.2925,0.49183487,4,0,,2.00E-60,Q8VCB2,Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25),Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25),GO:0048147; GO:0000122; GO:0005654; GO:0071158; GO:0035563; GO:2001178; GO:0045944; GO:0006351,"negative regulation of fibroblast proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of cell cycle arrest; positive regulation of chromatin binding; positive regulation of mediator complex assembly; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF11232;PF11244;PF11235;PF11265;,3.00E-54,CHOYP_MED25.2.2,,,,,,,MED25_MOUSE,Mus musculus (Mouse),"negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp132546_c0_seq3,697,39.7418,0.65540041,0,0,,,,,,,,,1.00E-37,CHOYP_MED25.2.2,,,,,,,,, comp132550_c0_seq1,1789,40.5254,1.05183431,64,231,,7.00E-33,Q11131,"Alpha-(1,3)-fucosyltransferase 7 (EC 2.4.1.-) (Fucosyltransferase 7) (Fucosyltransferase VII) (Fuc-TVII) (FucT-VII) (Galactoside 3-L-fucosyltransferase)","Alpha-(1,3)-fucosyltransferase 7 (EC 2.4.1.-) (Fucosyltransferase 7) (Fucosyltransferase VII) (Fuc-TVII) (FucT-VII) (Galactoside 3-L-fucosyltransferase)",GO:0002361; GO:0032580; GO:0036065; GO:0008417; GO:0016021; GO:0002522; GO:0006486,"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; Golgi cisterna membrane; fucosylation; fucosyltransferase activity; integral to membrane; leukocyte migration involved in immune response; protein glycosylation",PF17039;PF00852;,,,,,,,,,FUT7_MOUSE,Mus musculus (Mouse),"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; leukocyte migration involved in immune response [GO:0002522]; protein glycosylation [GO:0006486]" comp132551_c0_seq1,1618,37.7009,0.61907765,105,298,,2.00E-31,Q9CWK3,CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2),CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2),GO:0008380; GO:0005682; GO:0005737; GO:0006397; GO:0010923; GO:0016607; GO:0043021,RNA splicing; U5 snRNP; cytoplasm; mRNA processing; negative regulation of phosphatase activity; nuclear speck; ribonucleoprotein complex binding,PF02213;,8.00E-58,CHOYP_BRAFLDRAFT_85822.1.1,,,,,,,CD2B2_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; negative regulation of phosphatase activity [GO:0010923]; RNA splicing [GO:0008380] comp132553_c0_seq2,1305,34.636,0.48966009,19,49,,6.00E-83,Q5PQ76,Uncharacterized protein C1orf50 homolog,Uncharacterized protein C1orf50 homolog,,,PF10504;,2.00E-33,CHOYP_CA050.1.2,,,,,,,CA050_XENLA,Xenopus laevis (African clawed frog), comp132558_c2_seq1,862,42.9234,0.93914832,28,3,,1.00E-10,Q6GPJ8,Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2),Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2),GO:0030030; GO:0005737; GO:0005815,cell projection organization; cytoplasm; microtubule organizing center,,5.00E-13,CHOYP_LOC100368832.1.1,,,,,,,CEP97_XENLA,Xenopus laevis (African clawed frog),cell projection organization [GO:0030030] comp132558_c3_seq1,911,43.4687,0.67635106,0,39,,,,,,,,,,,3.00E-39,ruditapes_lrc36926,,,,,,, comp132558_c3_seq2,733,42.8377,0.83500745,11,6,,1.00E-36,P03952,Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) (PKK) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],GO:0002542; GO:0007597; GO:0022617; GO:0005615; GO:0042730; GO:0005886; GO:0031639; GO:0051919; GO:0006508; GO:0004252,"Factor XII activation; blood coagulation, intrinsic pathway; extracellular matrix disassembly; extracellular space; fibrinolysis; plasma membrane; plasminogen activation; positive regulation of fibrinolysis; proteolysis; serine-type endopeptidase activity",PF00024;PF00089;,,,,,,,,,KLKB1_HUMAN,Homo sapiens (Human),"blood coagulation, intrinsic pathway [GO:0007597]; extracellular matrix disassembly [GO:0022617]; Factor XII activation [GO:0002542]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]" comp132558_c3_seq3,692,41.6185,0.7688131,4,10,,1.00E-09,P23605,Achelase-2 (EC 3.4.21.-) (Achelase II),Achelase-2 (EC 3.4.21.-) (Achelase II),GO:0007596; GO:0005615; GO:0042730; GO:0006508; GO:0004252,blood coagulation; extracellular space; fibrinolysis; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,ACH2_LONAC,Lonomia achelous (Giant silkworm moth) (Saturnid moth),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730] comp132560_c0_seq2,993,38.57,0.43696193,0,3,,4.00E-14,A4K2V0,Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit),Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit),GO:0005741; GO:0006626,mitochondrial outer membrane; protein targeting to mitochondrion,PF00515;,,,,,,,,,TOM34_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein targeting to mitochondrion [GO:0006626] comp132560_c0_seq3,1489,39.2881,0.41724518,9,4,,8.00E-64,Q5U2X2,Sperm-associated antigen 1 (HSD-3.8) (Infertility-related sperm protein Spag-1),Sperm-associated antigen 1 (HSD-3.8) (Infertility-related sperm protein Spag-1),GO:0005525; GO:0005737; GO:0016787; GO:0007338,GTP binding; cytoplasm; hydrolase activity; single fertilization,PF13877;PF00515;PF13181;,3.00E-24,CHOYP_LOC100369340.1.1,,,,,,,SPAG1_RAT,Rattus norvegicus (Rat),axonemal dynein complex assembly [GO:0070286]; single fertilization [GO:0007338] comp132561_c1_seq1,1280,39.6875,0.99766416,15,8,,6.00E-14,Q4W8A2,Solute carrier family 22 member 8 (Organic anion transporter 3) (mkOAT3),Solute carrier family 22 member 8 (Organic anion transporter 3) (mkOAT3),GO:0016323; GO:0016021; GO:0015075; GO:0009636,basolateral plasma membrane; integral to membrane; ion transmembrane transporter activity; response to toxic substance,PF00083;,,,,,,,,,S22A8_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),ion transport [GO:0006811]; response to toxic substance [GO:0009636] comp132561_c1_seq2,1241,40.0483,1.00975675,0,33,,9.00E-37,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,1.00E-21,ruditapes_c27370,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp132562_c0_seq1,839,43.5042,0.72512127,98,94,,6.00E-75,Q8BH57,WD repeat-containing protein 48 (USP1-associated factor 1),WD repeat-containing protein 48 (USP1-associated factor 1),GO:0005764; GO:0005634; GO:0016579,lysosome; nucleus; protein deubiquitination,PF11816;PF00400;,7.00E-24,CHOYP_WDR48.1.2,,,,,,,WDR48_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; homeostasis of number of cells [GO:0048872]; male gonad development [GO:0008584]; multicellular organism growth [GO:0035264]; positive regulation of epithelial cell proliferation [GO:0050679]; protein deubiquitination [GO:0016579]; regulation of protein monoubiquitination [GO:1902525]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; spermatogenesis [GO:0007283] comp132562_c1_seq1,283,42.4028,0.31874697,12,6,,2.00E-12,Q54ZP5,WD repeat-containing protein 48 homolog,WD repeat-containing protein 48 homolog,,,PF11816;PF00400;,9.00E-23,CHOYP_WDR48.2.2,,,,,,,WDR48_DICDI,Dictyostelium discoideum (Slime mold), comp132565_c0_seq1,787,33.9263,0.62152213,5928,10527,,2.00E-34,Q9N2W7,Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (NADH-ubiquinone oxidoreductase 17.0 kDa subunit),Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (NADH-ubiquinone oxidoreductase 17.0 kDa subunit),GO:0008137; GO:0009055; GO:0005743; GO:0005739; GO:0070469,NADH dehydrogenase (ubiquinone) activity; electron carrier activity; mitochondrial inner membrane; mitochondrion; respiratory chain,PF05071;,6.00E-18,CHOYP_SMP_082940.1.1,2.00E-47,ruditapes2_c186,,,,,NDUAC_CAEEL,Caenorhabditis elegans, comp132566_c0_seq1,916,34.8253,0.57973832,3144,10728,,4.00E-66,P62878,"E3 ubiquitin-protein ligase RBX1 (EC 6.3.2.-) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]","E3 ubiquitin-protein ligase RBX1 (EC 6.3.2.-) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]",GO:0031462; GO:0031463; GO:0031464; GO:0031465; GO:0031466; GO:0006281; GO:0019788; GO:0019005; GO:0031146; GO:0005680; GO:0005829; GO:0008190; GO:0006513; GO:0045116; GO:0004842; GO:0008270,Cul2-RING ubiquitin ligase complex; Cul3-RING ubiquitin ligase complex; Cul4A-RING ubiquitin ligase complex; Cul4B-RING ubiquitin ligase complex; Cul5-RING ubiquitin ligase complex; DNA repair; NEDD8 ligase activity; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; anaphase-promoting complex; cytosol; eukaryotic initiation factor 4E binding; protein monoubiquitination; protein neddylation; ubiquitin-protein ligase activity; zinc ion binding,PF12678;,2.00E-87,CHOYP_RBX1A.1.1,7.00E-92,ruditapes2_c3942,,,,,RBX1_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein monoubiquitination [GO:0006513]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] comp132567_c0_seq1,1249,39.3915,0.33394021,56,326,,2.00E-44,Q96S44,TP53-regulating kinase (EC 2.7.11.1) (Atypical serine/threonine protein kinase TP53RK) (EKC/KEOPS complex subunit TP53RK) (EC 3.6.-.-) (Nori-2) (p53-related protein kinase),TP53-regulating kinase (EC 2.7.11.1) (Atypical serine/threonine protein kinase TP53RK) (EKC/KEOPS complex subunit TP53RK) (EC 3.6.-.-) (Nori-2) (p53-related protein kinase),GO:0005524; GO:0009103; GO:0016020; GO:0005634; GO:0002039; GO:0018108; GO:0004674; GO:0004713,ATP binding; lipopolysaccharide biosynthetic process; membrane; nucleus; p53 binding; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF06293;,1.00E-17,CHOYP_LOC100375324.1.1,2.00E-74,ruditapes_c19330,,,,,PRPK_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; tRNA processing [GO:0008033]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525] comp132568_c0_seq1,725,52.2759,0.79524924,1,31,,1.00E-22,P53775,Homeobox protein DLL-4 (XDLL-4),Homeobox protein DLL-4 (XDLL-4),GO:0007275; GO:0005634; GO:0003700; GO:0000976,multicellular organismal development; nucleus; sequence-specific DNA binding transcription factor activity; transcription regulatory region sequence-specific DNA binding,PF12413;PF00046;,,,,,,,,,DLL4_XENLA,Xenopus laevis (African clawed frog),"angiogenesis [GO:0001525]; regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; ventral spinal cord interneuron fate commitment [GO:0060579]; visual perception [GO:0007601]" comp132568_c0_seq2,2977,37.9241,0.94400829,7,1110,female>male,1.00E-24,P20009,Homeotic protein distal-less (Protein brista),Homeotic protein distal-less (Protein brista),GO:0007487; GO:0007469; GO:0048264; GO:0007480; GO:0007485; GO:0008587; GO:0007479; GO:0016319; GO:0010629; GO:0005634; GO:0042048; GO:0021553; GO:0045893; GO:0048728; GO:0003700; GO:0010092; GO:0000976; GO:0006351,"analia development; antennal development; determination of ventral identity; imaginal disc-derived leg morphogenesis; imaginal disc-derived male genitalia development; imaginal disc-derived wing margin morphogenesis; leg disc proximal/distal pattern formation; mushroom body development; negative regulation of gene expression; nucleus; olfactory behavior; olfactory nerve development; positive regulation of transcription, DNA-dependent; proboscis development; sequence-specific DNA binding transcription factor activity; specification of organ identity; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00046;,6.00E-44,CHOYP_DLX1.1.1,,,,,,,DLL_DROME,Drosophila melanogaster (Fruit fly),"analia development [GO:0007487]; antennal development [GO:0007469]; determination of ventral identity [GO:0048264]; genital disc development [GO:0035215]; imaginal disc-derived appendage morphogenesis [GO:0035114]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived male genitalia development [GO:0007485]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; leg disc proximal/distal pattern formation [GO:0007479]; mushroom body development [GO:0016319]; negative regulation of gene expression [GO:0010629]; olfactory behavior [GO:0042048]; olfactory nerve development [GO:0021553]; positive regulation of transcription, DNA-templated [GO:0045893]; proboscis development [GO:0048728]; proximal/distal pattern formation, imaginal disc [GO:0007449]; specification of organ identity [GO:0010092]; transcription, DNA-templated [GO:0006351]" comp132571_c0_seq1,954,40.6709,0.68820638,119,339,,3.00E-38,A1A4Q2,Prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1),Prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1),GO:0002161; GO:0006450,aminoacyl-tRNA editing activity; regulation of translational fidelity,PF04073;,3.00E-23,CHOYP_LOC575671.1.1,,,,,,,PRXD1_BOVIN,Bos taurus (Bovine), comp132578_c0_seq1,264,36.3636,0.94644215,14,29,,2.00E-21,Q9DCQ3,Vesicle transport protein GOT1A (Golgi transport 1 homolog A),Vesicle transport protein GOT1A (Golgi transport 1 homolog A),GO:0000139; GO:0016021; GO:0015031; GO:0016192,Golgi membrane; integral to membrane; protein transport; vesicle-mediated transport,PF04178;,4.00E-40,CHOYP_AAEL_AAEL010895.1.1,,,,,,,GOT1A_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp132578_c1_seq1,626,34.345,0.40060343,27,133,,2.00E-26,Q9CR60,Vesicle transport protein GOT1B (Golgi transport 1 homolog B),Vesicle transport protein GOT1B (Golgi transport 1 homolog B),GO:0000139; GO:0005783; GO:0016021; GO:0043123; GO:0015031; GO:0004871; GO:0016192,Golgi membrane; endoplasmic reticulum; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein transport; signal transducer activity; vesicle-mediated transport,PF04178;,,,,,,,,,GOT1B_MOUSE,Mus musculus (Mouse),positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp132580_c0_seq1,1785,40.3361,0.90334708,349,2748,,9.00E-66,P80229,Leukocyte elastase inhibitor (LEI) (Leukocyte neutral proteinase inhibitor) (LNPI) (Serpin B1),Leukocyte elastase inhibitor (LEI) (Leukocyte neutral proteinase inhibitor) (LNPI) (Serpin B1),GO:0005737; GO:0005615; GO:0004867,cytoplasm; extracellular space; serine-type endopeptidase inhibitor activity,PF00079;,1.00E-11,CHOYP_MPET_1013.2.2,,,,,,,ILEU_PIG,Sus scrofa (Pig), comp132584_c0_seq1,2570,36.3813,0.77946895,0,0,,4.00E-88,Q9GZ71,Tropomyosin,Tropomyosin,,,PF00261;,1.00E-52,CHOYP_TPM.15.19,,,,,,,TPM_HALDV,Haliotis diversicolor (Abalone) (Sulculus diversicolor), comp132584_c0_seq3,2448,36.8873,0.80788737,17,885,,1.00E-107,Q9GZ71,Tropomyosin,Tropomyosin,,,PF00261;,3.00E-78,CHOYP_TPM.12.19,0,ruditapes2_c1356,,,,,TPM_HALDV,Haliotis diversicolor (Abalone) (Sulculus diversicolor), comp132584_c0_seq4,2448,37.0915,0.82135825,527,7492,,8.00E-99,P42636,Tropomyosin-1 (Bg 39) (Tropomyosin I) (BgTMI) (TMI),Tropomyosin-1 (Bg 39) (Tropomyosin I) (BgTMI) (TMI),,,PF00261;,4.00E-26,CHOYP_TPM.9.19,0,ruditapes2_c24,,,,,TPM1_BIOGL,Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail), comp132584_c0_seq5,2448,35.9069,0.79976206,0,19,,,,,,,,,5.00E-31,CHOYP_TPM.11.19,4.00E-61,ruditapes2_lrc4150,,,,,,, comp132584_c0_seq6,2570,36.5759,0.79315692,7,70,,,,,,,,,4.00E-26,CHOYP_TPM.19.19,1.00E-37,ruditapes_c6739,,,,,,, comp132587_c0_seq1,1446,42.1162,0.53435455,18,57,,2.00E-81,P56603,Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) (SCAMP 37),Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) (SCAMP 37),GO:0005794; GO:0006897; GO:0016021; GO:0019904; GO:0015031; GO:0055038; GO:0005802,Golgi apparatus; endocytosis; integral to membrane; protein domain specific binding; protein transport; recycling endosome membrane; trans-Golgi network,PF04144;,2.00E-77,CHOYP_SCAM1.1.1,,,,,,,SCAM1_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; protein transport [GO:0015031] comp132587_c0_seq3,910,41.978,0.47458382,0,13,,,,,,,,,3.00E-16,CHOYP_contig_036536,,,,,,,,, comp132597_c0_seq1,3476,35.8746,0.57035624,4054,29631,,0,P18298,S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II),S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II),GO:0005524; GO:0006556; GO:0016597; GO:0007623; GO:0005829; GO:0046872; GO:0004478; GO:0006730; GO:0051591; GO:0042493; GO:0009725; GO:0009416,ATP binding; S-adenosylmethionine biosynthetic process; amino acid binding; circadian rhythm; cytosol; metal ion binding; methionine adenosyltransferase activity; one-carbon metabolic process; response to cAMP; response to drug; response to hormone stimulus; response to light stimulus,PF02773;PF02772;PF00438;,0,CHOYP_METK.1.2,,,,,,,METK2_RAT,Rattus norvegicus (Rat),circadian rhythm [GO:0007623]; one-carbon metabolic process [GO:0006730]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to light stimulus [GO:0009416]; S-adenosylmethionine biosynthetic process [GO:0006556] comp132598_c0_seq1,2016,42.0139,0.57580199,260,343,,1.00E-35,Q2PFW9,RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Ventral neuron-specific protein 1),RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Ventral neuron-specific protein 1),GO:0003723; GO:0005634,RNA binding; nucleus,PF00013;,5.00E-68,CHOYP_ISCW_ISCW019027.2.2,,,,,,,NOVA1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"mRNA splicing, via spliceosome [GO:0000398]" comp132601_c0_seq1,871,39.2652,0.57613874,0,0,,3.00E-48,Q6PAJ1,Breakpoint cluster region protein (EC 2.7.11.1),Breakpoint cluster region protein (EC 2.7.11.1),GO:0005524; GO:0030675; GO:0005089; GO:0030036; GO:0007420; GO:0005829; GO:0042472; GO:0035556; GO:0030336; GO:0050728; GO:0043314; GO:0050885; GO:0005543; GO:0005886; GO:0050766; GO:0004674; GO:0051726; GO:0032496,ATP binding; Rac GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; brain development; cytosol; inner ear morphogenesis; intracellular signal transduction; negative regulation of cell migration; negative regulation of inflammatory response; negative regulation of neutrophil degranulation; neuromuscular process controlling balance; phospholipid binding; plasma membrane; positive regulation of phagocytosis; protein serine/threonine kinase activity; regulation of cell cycle; response to lipopolysaccharide,PF09036;PF00168;PF00620;PF00621;,4.00E-14,CHOYP_LOC100176232.1.1,,,,,,,BCR_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496] comp132601_c0_seq8,838,39.6181,0.52865161,6,29,,4.00E-59,Q6PAJ1,Breakpoint cluster region protein (EC 2.7.11.1),Breakpoint cluster region protein (EC 2.7.11.1),GO:0005524; GO:0030675; GO:0005089; GO:0030036; GO:0007420; GO:0005829; GO:0042472; GO:0035556; GO:0030336; GO:0050728; GO:0043314; GO:0050885; GO:0005543; GO:0005886; GO:0050766; GO:0004674; GO:0051726; GO:0032496,ATP binding; Rac GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; brain development; cytosol; inner ear morphogenesis; intracellular signal transduction; negative regulation of cell migration; negative regulation of inflammatory response; negative regulation of neutrophil degranulation; neuromuscular process controlling balance; phospholipid binding; plasma membrane; positive regulation of phagocytosis; protein serine/threonine kinase activity; regulation of cell cycle; response to lipopolysaccharide,PF09036;PF00168;PF00620;PF00621;,4.00E-14,CHOYP_LOC100176232.1.1,2.00E-21,ruditapes_c7261,,,,,BCR_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496] comp132604_c0_seq1,929,39.6125,0.24748698,5,0,,1.00E-47,Q8W4K1,tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (EC 2.1.1.282); tRNA wybutosine-synthesizing protein 2 homolog (EC 2.5.1.-)],tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)],GO:0008168; GO:0031591,methyltransferase activity; wybutosine biosynthetic process,PF01344;PF02475;PF02676;,,,,,,,,,TYW23_ARATH,Arabidopsis thaliana (Mouse-ear cress),wybutosine biosynthetic process [GO:0031591] comp132604_c0_seq2,986,39.4523,0.2612911,2,22,,2.00E-61,Q0P466,tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.1.1.-) (Alpha-amino-alpha-carboxypropyl transferase TYW2) (EC 2.5.1.-),tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase),GO:0008168; GO:0008033,methyltransferase activity; tRNA processing,PF02475;,,,,,,,,,TYW2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),tRNA processing [GO:0008033] comp132605_c0_seq1,1082,39.9261,0.94214957,15,101,,1.00E-13,P39865,Nitrate reductase [NADH] 1 (NR-1) (EC 1.7.1.1),Nitrate reductase [NADH] 1 (NR-1) (EC 1.7.1.1),GO:0009055; GO:0050660; GO:0020037; GO:0005506; GO:0030151; GO:0043546; GO:0042128; GO:0009703,electron carrier activity; flavin adenine dinucleotide binding; heme binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; nitrate assimilation; nitrate reductase (NADH) activity,PF00173;PF00970;PF03404;PF00175;PF00174;,,,,,,,,,NIA1_PHAVU,Phaseolus vulgaris (Kidney bean) (French bean),nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809] comp132605_c0_seq2,703,39.4026,0.88926496,2,12,,3.00E-20,P00173,Cytochrome b5,Cytochrome b5,GO:0009055; GO:0005789; GO:0020037; GO:0016021; GO:0046872; GO:0055114; GO:0046686,electron carrier activity; endoplasmic reticulum membrane; heme binding; integral to membrane; metal ion binding; oxidation-reduction process; response to cadmium ion,PF00173;,,,,,,,,,CYB5_RAT,Rattus norvegicus (Rat),oxidation-reduction process [GO:0055114]; response to cadmium ion [GO:0046686] comp132606_c0_seq1,1239,38.0145,0.66815354,26,27,,2.00E-43,Q9H2C0,Gigaxonin (Kelch-like protein 16),Gigaxonin (Kelch-like protein 16),GO:0031463; GO:0008219; GO:0005737; GO:0005883; GO:0016567,Cul3-RING ubiquitin ligase complex; cell death; cytoplasm; neurofilament; protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,GAN_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp132606_c0_seq2,1199,38.6989,0.51242272,21,0,,4.00E-21,B4QLQ2,Kelch-like protein diablo,Kelch-like protein diablo,GO:0016049; GO:0016567; GO:0050807,cell growth; protein ubiquitination; regulation of synapse organization,PF07707;PF00651;PF01344;,,,,,,,,,KLHDB_DROSI,Drosophila simulans (Fruit fly),cell growth [GO:0016049]; protein ubiquitination [GO:0016567]; regulation of synapse organization [GO:0050807] comp132608_c0_seq2,349,39.5415,0.30668379,6,0,,3.00E-09,Q22795,Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),GO:0009792; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"embryo development ending in birth or egg hatching; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET1_CAEEL,Caenorhabditis elegans,"embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132609_c0_seq2,789,33.5868,0.54564379,71,145,,8.00E-23,P24369,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),GO:0005788; GO:0042470; GO:0042277; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum lumen; melanosome; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,,,1.00E-18,ruditapes_lrc15083,,,,,PPIB_MOUSE,Mus musculus (Mouse),bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] comp132613_c0_seq1,1514,38.8375,0.56403599,161,368,,7.00E-41,Q9H8P0,Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3),Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3),GO:0003865; GO:0006702; GO:0047751; GO:0019348; GO:0006488; GO:0005789; GO:0016021; GO:0016628; GO:0016095; GO:0006486,"3-oxo-5-alpha-steroid 4-dehydrogenase activity; androgen biosynthetic process; cholestenone 5-alpha-reductase activity; dolichol metabolic process; dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum membrane; integral to membrane; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; polyprenol catabolic process; protein glycosylation",PF02544;,,,,,,,,,PORED_HUMAN,Homo sapiens (Human),androgen biosynthetic process [GO:0006702]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichol metabolic process [GO:0019348]; dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol catabolic process [GO:0016095]; protein glycosylation [GO:0006486] comp132617_c0_seq1,1405,39.2883,0.35746419,0,0,,1.00E-169,Q8WU10,Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-),Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-),GO:0016491,oxidoreductase activity,PF07992;,,,,,,,,,PYRD1_HUMAN,Homo sapiens (Human), comp132617_c0_seq2,1334,38.6807,0.3469761,0,0,,1.00E-87,Q54H36,Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-),Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-),GO:0016491,oxidoreductase activity,PF07992;,7.00E-83,CHOYP_PYRD1.1.1,,,,,,,PYRD1_DICDI,Dictyostelium discoideum (Slime mold), comp132617_c0_seq3,949,40.6744,0.28533234,0,0,,1.00E-08,Q49WB0,Coenzyme A disulfide reductase (CoA-disulfide reductase) (CoADR) (EC 1.8.1.14),Coenzyme A disulfide reductase (CoA-disulfide reductase) (CoADR) (EC 1.8.1.14),GO:0050451; GO:0050661; GO:0045454; GO:0050660; GO:0003756; GO:0006457,CoA-disulfide reductase activity; NADP binding; cell redox homeostasis; flavin adenine dinucleotide binding; protein disulfide isomerase activity; protein folding,PF07992;PF02852;,,,,,,,,,CDR_STAS1,Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229),cell redox homeostasis [GO:0045454] comp132618_c5_seq1,684,30.117,0.83938345,15,134,,,,,,,,,,,9.00E-13,ruditapes_c8275,,,,,,, comp132618_c5_seq2,254,26.7717,1.16760052,0,18,,,,,,,,,,,5.00E-11,ruditapes_c20166,,,,,,, comp132624_c0_seq1,1261,38.858,0.48907342,254,123,,3.00E-47,Q810N6,Ankyrin repeat domain-containing protein 45,Ankyrin repeat domain-containing protein 45,,,PF12796;,,,4.00E-20,ruditapes_c20548,,,,,ANR45_MOUSE,Mus musculus (Mouse), comp132624_c0_seq2,1250,38.72,0.47461574,10,53,,8.00E-42,Q5TZF3,Ankyrin repeat domain-containing protein 45,Ankyrin repeat domain-containing protein 45,,,PF12796;,2.00E-33,CHOYP_LOC100185472.1.1,7.00E-55,ruditapes2_c1627,,,,,ANR45_HUMAN,Homo sapiens (Human), comp132628_c1_seq1,1422,43.3193,0.55840644,50,18,,,,,,,,,4.00E-55,CHOYP_BRAFLDRAFT_69036.1.1,,,,,,,,, comp132630_c0_seq2,2707,35.0203,0.39894648,253,338,,8.00E-133,O75521,"Enoyl-CoA delta isomerase 2, mitochondrial (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1)","Enoyl-CoA delta isomerase 2, mitochondrial (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1)",GO:0004165; GO:0009062; GO:0000062; GO:0005739; GO:0005782,dodecenoyl-CoA delta-isomerase activity; fatty acid catabolic process; fatty-acyl-CoA binding; mitochondrion; peroxisomal matrix,PF00887;PF00378;,8.00E-105,CHOYP_BRAFLDRAFT_57395.1.1,1.00E-17,ruditapes_c24871,,,,,ECI2_HUMAN,Homo sapiens (Human),cellular lipid metabolic process [GO:0044255]; fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062] comp132636_c0_seq1,1686,36.4769,0.46574515,53,60,,8.00E-137,A4IGM9,Aurora kinase B (EC 2.7.11.1) (Aurora/IPL1-related kinase 2) (AIRK2) (XAIRK2) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase aurora-B) (xAurora-B),Aurora kinase B (EC 2.7.11.1) (Aurora/IPL1-related kinase 2) (AIRK2) (XAIRK2) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase aurora-B) (xAurora-B),GO:0005524; GO:0034644; GO:0000785; GO:0032133; GO:0007059; GO:0000775; GO:0036089; GO:0035175; GO:0046872; GO:0002903; GO:0000122; GO:0005634; GO:0032467; GO:0034501; GO:0051256,"ATP binding; cellular response to UV; chromatin; chromosome passenger complex; chromosome segregation; chromosome, centromeric region; cleavage furrow formation; histone kinase activity (H3-S10 specific); metal ion binding; negative regulation of B cell apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of cytokinesis; protein localization to kinetochore; spindle midzone assembly involved in mitosis",PF00069;,,,,,,,,,AURKB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),abscission [GO:0009838]; cellular response to UV [GO:0034644]; cleavage furrow formation [GO:0036089]; histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cytokinesis [GO:0032466]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cytokinesis [GO:0032467]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of cytokinesis [GO:0032465]; spindle assembly [GO:0051225]; spindle checkpoint [GO:0031577] comp132636_c0_seq2,1335,39.4007,0.44533358,34,108,,8.00E-155,Q2TA06,Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A),Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A),GO:0005524; GO:0051301; GO:0030030; GO:0005737; GO:0005874; GO:0005815; GO:0007067; GO:0004672; GO:0004674; GO:0000922,ATP binding; cell division; cell projection organization; cytoplasm; microtubule; microtubule organizing center; mitosis; protein kinase activity; protein serine/threonine kinase activity; spindle pole,PF00069;,2.00E-97,CHOYP_AURKA.1.1,,,,,,,AURKA_BOVIN,Bos taurus (Bovine),anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization to centrosome [GO:0071539]; regulation of cytokinesis [GO:0032465]; regulation of protein stability [GO:0031647]; spindle assembly involved in female meiosis I [GO:0007057] comp132637_c1_seq1,969,41.2797,0.53542811,57,72,,7.00E-11,Q8TB03,Uncharacterized protein CXorf38,Uncharacterized protein CXorf38,,,PF15112;,,,,,,,,,CX038_HUMAN,Homo sapiens (Human), comp132641_c0_seq2,1816,44.3833,0.42705357,0,0,,6.00E-35,Q3T8J9,GON-4-like protein (GON-4 homolog),GON-4-like protein (GON-4 homolog),GO:0030183; GO:0003677; GO:0003682; GO:0005634; GO:0006355,"B cell differentiation; DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent",PF02671;,,,,,,,,,GON4L_HUMAN,Homo sapiens (Human),"B cell differentiation [GO:0030183]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp132641_c0_seq7,1941,44.6677,0.43679724,0,0,,1.00E-09,Q9H869,YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2),YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2),GO:0005737; GO:0005634; GO:0051726; GO:0006355; GO:0006351,"cytoplasm; nucleus; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,YYAP1_HUMAN,Homo sapiens (Human),"regulation of cell cycle [GO:0051726]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132641_c1_seq1,2557,40.9464,0.28975566,183,230,,1.00E-37,Q3T8J9,GON-4-like protein (GON-4 homolog),GON-4-like protein (GON-4 homolog),GO:0030183; GO:0003677; GO:0003682; GO:0005634; GO:0006355,"B cell differentiation; DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent",PF02671;,,,,,,,,,GON4L_HUMAN,Homo sapiens (Human),"B cell differentiation [GO:0030183]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp132650_c0_seq2,584,42.4658,0.7405085,0,0,,,,,,,,,2.00E-47,CHOYP_LOC100377113.3.3,,,,,,,,, comp132650_c0_seq5,722,41.8283,0.73485934,4,5,,,,,,,,,1.00E-50,CHOYP_LOC100377113.2.3,,,,,,,,, comp132653_c0_seq3,800,37.25,0.29448575,42,55,,1.00E-17,Q9CPT4,UPF0556 protein C19orf10 homolog (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20),Myeloid-derived growth factor (MYDGF) (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20),GO:0005576,extracellular region,PF10572;,,,,,,,,,CS010_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp132656_c1_seq1,991,37.0333,0.56990866,52,97,,4.00E-113,Q5XIP1,Protein pelota homolog (EC 3.1.-.-),Protein pelota homolog (EC 3.1.-.-),GO:0007049; GO:0051301; GO:0008283; GO:0051276; GO:0005737; GO:0004519; GO:0046872; GO:0090305; GO:0005634,cell cycle; cell division; cell proliferation; chromosome organization; cytoplasm; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF03463;PF03464;PF03465;,3.00E-86,CHOYP_PELO.1.1,,,,,,,PELO_RAT,Rattus norvegicus (Rat),"cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; chromosome organization [GO:0051276]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; RNA surveillance [GO:0071025]" comp132658_c0_seq2,339,40.413,0.72464399,3,2,,,,,,,,,8.00E-18,CHOYP_LOC100904451.9.11,,,,,,,,, comp132658_c0_seq3,842,37.1734,0.61970193,30,1,,,,,,,,,3.00E-16,CHOYP_LOC100904451.2.11,,,,,,,,, comp132664_c1_seq1,740,41.6216,0.25516576,2,0,,,,,,,,,3.00E-34,CHOYP_LOC100765748.1.1,,,,,,,,, comp132664_c1_seq2,753,41.6999,0.24875296,2,17,,3.00E-46,Q68FT1,"Ubiquinone biosynthesis protein COQ9, mitochondrial","Ubiquinone biosynthesis protein COQ9, mitochondrial",GO:0005739; GO:0006744,mitochondrion; ubiquinone biosynthetic process,PF08511;,,,,,,,,,COQ9_RAT,Rattus norvegicus (Rat),"mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; ubiquinone biosynthetic process [GO:0006744]" comp132666_c0_seq1,1279,38.0766,0.45878164,24,392,,,,,,,,,2.00E-51,CHOYP_DICPUDRAFT_80174.1.1,,,,,,,,, comp132668_c0_seq1,540,32.2222,1.21766603,93,294,,,,,,,,,,,3.00E-17,ruditapes_lrc23864,,,,,,, comp132672_c0_seq1,1699,37.4926,0.77710451,263,1848,,6.00E-39,Q9QWG7,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-) (DOPA/tyrosine sulfotransferase),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-) (DOPA/tyrosine sulfotransferase),GO:0004062; GO:0005829; GO:0009812; GO:0008202; GO:0051923; GO:0042403; GO:0006805,aryl sulfotransferase activity; cytosol; flavonoid metabolic process; steroid metabolic process; sulfation; thyroid hormone metabolic process; xenobiotic metabolic process,PF00685;,4.00E-11,CHOYP_LOC100459096.3.3,,,,,,,ST1B1_MOUSE,Mus musculus (Mouse),epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp132672_c0_seq2,830,39.6386,0.67566067,3,83,,2.00E-31,P0CC03,Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2),Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,,,,,,,,,ST6B1_MOUSE,Mus musculus (Mouse), comp132674_c0_seq1,1855,39.2453,0.57727221,134,622,,0,Q5R8R1,Actin-related protein 3 (Actin-like protein 3),Actin-related protein 3 (Actin-like protein 3),GO:0005524; GO:0008356; GO:0060271; GO:0005737; GO:0005856; GO:0007163; GO:0030027; GO:0033206; GO:0051653,ATP binding; asymmetric cell division; cilium morphogenesis; cytoplasm; cytoskeleton; establishment or maintenance of cell polarity; lamellipodium; meiotic cytokinesis; spindle localization,PF00022;,0,CHOYP_ARP3.1.1,,,,,,,ARP3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),Arp2/3 complex-mediated actin nucleation [GO:0034314]; asymmetric cell division [GO:0008356]; cilium morphogenesis [GO:0060271]; establishment or maintenance of cell polarity [GO:0007163]; meiotic chromosome movement towards spindle pole [GO:0016344]; meiotic cytokinesis [GO:0033206]; spindle localization [GO:0051653] comp132677_c0_seq1,853,40.9144,0.87390362,1,331,female>male,2.00E-45,P32320,Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase),Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase),GO:0007166; GO:0004126; GO:0019858; GO:0005829; GO:0005576; GO:0030308; GO:0045980; GO:0001882; GO:0042803; GO:0051289; GO:0043097; GO:0008270,cell surface receptor signaling pathway; cytidine deaminase activity; cytosine metabolic process; cytosol; extracellular region; negative regulation of cell growth; negative regulation of nucleotide metabolic process; nucleoside binding; protein homodimerization activity; protein homotetramerization; pyrimidine nucleoside salvage; zinc ion binding,PF00383;,8.00E-42,CHOYP_LOC100693418.1.2,,,,,,,CDD_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside salvage [GO:0043097] comp132678_c1_seq1,809,42.5216,0.60902349,72,265,,5.00E-22,Q5NVI6,Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor),Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor),GO:0005737; GO:0016021; GO:0007275; GO:0005634; GO:0005886; GO:0004872,cytoplasm; integral to membrane; multicellular organismal development; nucleus; plasma membrane; receptor activity,,3.00E-21,CHOYP_PTTG1IP.1.1.1,,,,,,,PTTG_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp132680_c0_seq1,304,47.0395,0.71765482,7,22,,4.00E-40,Q9CY52,Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase),Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase),GO:0005524; GO:0005525; GO:0005737; GO:0000287; GO:0005739; GO:0051289; GO:0008193; GO:0006400,ATP binding; GTP binding; cytoplasm; magnesium ion binding; mitochondrion; protein homotetramerization; tRNA guanylyltransferase activity; tRNA modification,PF04446;PF14413;,4.00E-27,CHOYP_LOC100075219.1.1,,,,,,,THG1_MOUSE,Mus musculus (Mouse),protein homotetramerization [GO:0051289]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] comp132682_c1_seq1,219,43.379,0.68628882,1,0,,4.00E-27,Q92870,Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1),Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1),GO:0007411; GO:0001540; GO:0007050; GO:0005737; GO:0030198; GO:0030426; GO:0035556; GO:0030027; GO:0016020; GO:0043066; GO:0030308; GO:0001764; GO:0005634; GO:0043065; GO:0006355; GO:0045202; GO:0008134,"axon guidance; beta-amyloid binding; cell cycle arrest; cytoplasm; extracellular matrix organization; growth cone; intracellular signal transduction; lamellipodium; membrane; negative regulation of apoptotic process; negative regulation of cell growth; neuron migration; nucleus; positive regulation of apoptotic process; regulation of transcription, DNA-dependent; synapse; transcription factor binding",PF00640;PF00397;,2.00E-42,CHOYP_PHUM_PHUM122670.1.1,,,,,,,APBB2_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; regulation of transcription, DNA-templated [GO:0006355]" comp132683_c0_seq2,1168,36.9007,0.95658798,0,51,,2.00E-14,Q86Z23,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_HUMAN,Homo sapiens (Human),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp132685_c1_seq1,1113,40.9704,0.82771903,110,94,,4.00E-108,Q5F3A6,Ubiquitin thioesterase OTU1 (EC 3.4.19.12),Ubiquitin thioesterase OTU1 (EC 3.4.19.12),GO:0030433; GO:0006520; GO:0030968; GO:0046872; GO:0035871; GO:1990167; GO:0035523; GO:1990168; GO:0071108; GO:0070536; GO:0004843,ER-associated protein catabolic process; cellular amino acid metabolic process; endoplasmic reticulum unfolded protein response; metal ion binding; protein K11-linked deubiquitination; protein K27-linked deubiquitination; protein K29-linked deubiquitination; protein K33-linked deubiquitination; protein K48-linked deubiquitination; protein K63-linked deubiquitination; ubiquitin-specific protease activity,PF02338;,1.00E-47,CHOYP_OTU1.1.1,,,,,,,OTU1_CHICK,Gallus gallus (Chicken),endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein K11-linked deubiquitination [GO:0035871]; protein K27-linked deubiquitination [GO:1990167]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536] comp132688_c2_seq1,1196,38.2943,0.42974281,16,143,,3.00E-71,Q9ULC3,Ras-related protein Rab-23,Ras-related protein Rab-23,GO:0005525; GO:0003924; GO:0005776; GO:0000045; GO:0006968; GO:0097094; GO:0042733; GO:0010008; GO:0045861; GO:0042992; GO:0045335; GO:0030670; GO:0005886; GO:0015031; GO:0008589; GO:0007264; GO:0021513,GTP binding; GTPase activity; autophagic vacuole; autophagic vacuole assembly; cellular defense response; craniofacial suture morphogenesis; embryonic digit morphogenesis; endosome membrane; negative regulation of proteolysis; negative regulation of transcription factor import into nucleus; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; protein transport; regulation of smoothened signaling pathway; small GTPase mediated signal transduction; spinal cord dorsal/ventral patterning,PF00071;,2.00E-103,CHOYP_BRAFLDRAFT_62225.1.1,,,,,,,RAB23_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; cellular defense response [GO:0006968]; cilium assembly [GO:0042384]; craniofacial suture morphogenesis [GO:0097094]; negative regulation of transcription factor import into nucleus [GO:0042992]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp132689_c0_seq1,1317,37.5095,1.14135424,190,461,,4.00E-34,Q03017,NF-kappa-B inhibitor cactus,NF-kappa-B inhibitor cactus,GO:0008063; GO:0019732; GO:0005737; GO:0042994; GO:0046843; GO:0009950; GO:0030097; GO:0045087; GO:0007399; GO:0031594; GO:0006909; GO:0006967; GO:0006974; GO:0008134,Toll signaling pathway; antifungal humoral response; cytoplasm; cytoplasmic sequestering of transcription factor; dorsal appendage formation; dorsal/ventral axis specification; hemopoiesis; innate immune response; nervous system development; neuromuscular junction; phagocytosis; positive regulation of antifungal peptide biosynthetic process; response to DNA damage stimulus; transcription factor binding,PF00023;PF12796;,,,,,,,,,CACT_DROME,Drosophila melanogaster (Fruit fly),antifungal humoral response [GO:0019732]; antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic sequestering of transcription factor [GO:0042994]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal appendage formation [GO:0046843]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of protein import into nucleus [GO:0042308]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of antifungal peptide biosynthetic process [GO:0006967]; response to fungus [GO:0009620]; Toll signaling pathway [GO:0008063] comp132690_c0_seq1,1200,39.3333,0.54425691,0,0,,2.00E-108,Q9BXB4,Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),GO:0005794; GO:0045444; GO:0031902; GO:0006869; GO:0005543; GO:0010890,Golgi apparatus; fat cell differentiation; late endosome membrane; lipid transport; phospholipid binding; positive regulation of sequestering of triglyceride,PF01237;PF00169;,,,,,,,,,OSB11_HUMAN,Homo sapiens (Human),fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890] comp132690_c0_seq2,2160,42.5463,0.49207309,2,0,,5.00E-175,Q9BXB4,Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),GO:0005794; GO:0045444; GO:0031902; GO:0006869; GO:0005543; GO:0010890,Golgi apparatus; fat cell differentiation; late endosome membrane; lipid transport; phospholipid binding; positive regulation of sequestering of triglyceride,PF01237;PF00169;,2.00E-66,CHOYP_BRAFLDRAFT_226345.1.1,,,,,,,OSB11_HUMAN,Homo sapiens (Human),fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890] comp132696_c0_seq10,521,44.9136,0.80668485,2,8,,6.00E-11,Q8WXS8,A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-),GO:0030574; GO:0030199; GO:0030198; GO:0005576; GO:0004222; GO:0005578; GO:0006508; GO:0008270,collagen catabolic process; collagen fibril organization; extracellular matrix organization; extracellular region; metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS14_HUMAN,Homo sapiens (Human),collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199] comp132696_c0_seq2,919,48.6398,0.83887277,0,2,,3.00E-43,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp132696_c0_seq4,1133,48.1906,0.81913029,0,0,,6.00E-30,Q28178,Thrombospondin-1,Thrombospondin-1,GO:0048266; GO:0005509; GO:0007155; GO:0005576; GO:0008201; GO:0034976; GO:0016529,behavioral response to pain; calcium ion binding; cell adhesion; extracellular region; heparin binding; response to endoplasmic reticulum stress; sarcoplasmic reticulum,PF12662;PF02210;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP1_BOVIN,Bos taurus (Bovine),behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] comp132696_c0_seq5,873,46.9645,0.84249195,5,0,,3.00E-43,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp132696_c0_seq6,1146,47.1204,0.79524715,0,0,,6.00E-25,Q95116,Thrombospondin-2 (Corticotropin-induced secreted protein) (CISP),Thrombospondin-2 (Corticotropin-induced secreted protein) (CISP),GO:0005509; GO:0007155; GO:0005576; GO:0008201,calcium ion binding; cell adhesion; extracellular region; heparin binding,PF12947;PF07645;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP2_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525] comp132697_c0_seq1,1033,40.9487,0.59768842,1325,4787,,2.00E-57,Q6PBE2,Pre-mRNA-splicing factor SPF27 (Protein BCAS2 homolog),Pre-mRNA-splicing factor SPF27 (Protein BCAS2 homolog),GO:0008380; GO:0006397; GO:0005681,RNA splicing; mRNA processing; spliceosomal complex,PF05700;,3.00E-93,CHOYP_BRAFLDRAFT_115639.1.1,,,,,,,SPF27_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"mRNA splicing, via spliceosome [GO:0000398]" comp132699_c0_seq2,1329,38.9014,0.42145791,171,309,,1.00E-63,P43234,Cathepsin O (EC 3.4.22.42),Cathepsin O (EC 3.4.22.42),GO:0004197; GO:0005764; GO:0006508,cysteine-type endopeptidase activity; lysosome; proteolysis,PF00112;,4.00E-29,CHOYP_ISCW_ISCW017550.1.1,,,,,,,CATO_HUMAN,Homo sapiens (Human),proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp132702_c1_seq1,1746,45.5326,0.43251269,5,12,,2.00E-64,Q6ZQ06,Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog),Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog),GO:0005879; GO:0005814; GO:0042384; GO:0005634; GO:0005886; GO:0005819,axonemal microtubule; centriole; cilium assembly; nucleus; plasma membrane; spindle,,,,,,,,,,QN1_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384] comp132702_c1_seq3,1402,45.8631,0.50770291,3,0,,,,,,,,,3.00E-25,CHOYP_KIAA1009.1.1,,,,,,,,, comp132704_c0_seq3,971,41.0917,0.51888814,500,232,,2.00E-26,P46013,Antigen KI-67,Antigen KI-67,GO:0005524; GO:0006259; GO:0008283; GO:0034605; GO:0000775; GO:0000793; GO:0005737; GO:0007126; GO:0005730; GO:0031100,"ATP binding; DNA metabolic process; cell proliferation; cellular response to heat; chromosome, centromeric region; condensed chromosome; cytoplasm; meiosis; nucleolus; organ regeneration",PF00498;PF08065;PF15276;,,,,,,,,,KI67_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; cellular response to heat [GO:0034605]; cholangiocyte proliferation [GO:1990705]; DNA metabolic process [GO:0006259]; hepatocyte proliferation [GO:0072574]; hyaluronan metabolic process [GO:0030212]; meiotic nuclear division [GO:0007126]; organ regeneration [GO:0031100]; response to organic cyclic compound [GO:0014070] comp132708_c0_seq1,769,37.7113,0.56617743,107,789,,4.00E-44,Q5M882,Ribonuclease P protein subunit p29 (EC 3.1.26.5),Ribonuclease P protein subunit p29 (EC 3.1.26.5),GO:0003723; GO:0006379; GO:0005655; GO:0006364; GO:0000172; GO:0004526; GO:0008033,RNA binding; mRNA cleavage; nucleolar ribonuclease P complex; rRNA processing; ribonuclease MRP complex; ribonuclease P activity; tRNA processing,PF01868;,,,,,,,,,RPP29_RAT,Rattus norvegicus (Rat),mRNA cleavage [GO:0006379]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033] comp132708_c5_seq1,892,43.0493,1.14552943,2,39,,6.00E-08,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,,,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp132710_c0_seq1,2337,41.335,0.4114078,1275,9193,,5.00E-150,Q9NRG9,Aladin (Adracalin),Aladin (Adracalin),GO:0005975; GO:0005813; GO:0019221; GO:0005737; GO:0009566; GO:0015758; GO:0007612; GO:0007077; GO:0031965; GO:0005643; GO:0006913; GO:0010827; GO:0046822; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; centrosome; cytokine-mediated signaling pathway; cytoplasm; fertilization; glucose transport; learning; mitotic nuclear envelope disassembly; nuclear membrane; nuclear pore; nucleocytoplasmic transport; regulation of glucose transport; regulation of nucleocytoplasmic transport; small molecule metabolic process; transmembrane transport; viral process,,3.00E-78,CHOYP_LOC100366577.1.2,,,,,,,AAAS_HUMAN,Homo sapiens (Human),fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; learning [GO:0007612]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of nucleocytoplasmic transport [GO:0046822]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp132713_c0_seq1,1498,33.4446,0.31207176,9,120,,3.00E-32,O14880,Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III),Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III),GO:0005789; GO:1901687; GO:0004602; GO:0004364; GO:0016021; GO:0006629; GO:0005635; GO:0007165; GO:0044281; GO:0006805,endoplasmic reticulum membrane; glutathione derivative biosynthetic process; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; lipid metabolic process; nuclear envelope; signal transduction; small molecule metabolic process; xenobiotic metabolic process,PF01124;,,,,,,,,,MGST3_HUMAN,Homo sapiens (Human),glutathione derivative biosynthetic process [GO:1901687]; lipid metabolic process [GO:0006629]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165]; xenobiotic metabolic process [GO:0006805] comp132717_c0_seq2,2088,42.3851,0.96476756,16,98,,9.00E-38,Q9QYG6,Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27),Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27),GO:0005789; GO:0020037; GO:0005506; GO:0016712,"endoplasmic reticulum membrane; heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",PF00067;,,,,,,,,,CP2DR_MESAU,Mesocricetus auratus (Golden hamster), comp132721_c0_seq2,853,41.9695,0.7008848,31,24,,5.00E-60,Q9D0P0,Emopamil-binding protein-like (Emopamil-binding-related protein),Emopamil-binding protein-like (Emopamil-binding-related protein),GO:0047750; GO:0005789; GO:0016021; GO:0016125,cholestenol delta-isomerase activity; endoplasmic reticulum membrane; integral to membrane; sterol metabolic process,PF05241;,3.00E-35,CHOYP_EBPL.1.1,,,,,,,EBPL_MOUSE,Mus musculus (Mouse),sterol metabolic process [GO:0016125] comp132721_c0_seq3,659,44.4613,0.80112229,10,5,,1.00E-52,Q9BY08,Emopamil-binding protein-like (Emopamil-binding-related protein),Emopamil-binding protein-like (Emopamil-binding-related protein),GO:0047750; GO:0005789; GO:0016021; GO:0016125,cholestenol delta-isomerase activity; endoplasmic reticulum membrane; integral to membrane; sterol metabolic process,PF05241;,2.00E-30,CHOYP_EBPL.1.1,,,,,,,EBPL_HUMAN,Homo sapiens (Human),sterol metabolic process [GO:0016125] comp132723_c0_seq1,2082,45.245,0.46222448,96,255,,0,Q9H9Y6,DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),GO:0003677; GO:0005736; GO:0003899; GO:0005737; GO:0009790; GO:0007566; GO:0046872; GO:0017126; GO:0005654; GO:0009303; GO:0032549; GO:0006363; GO:0006362; GO:0006361,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; cytoplasm; embryo development; embryo implantation; metal ion binding; nucleologenesis; nucleoplasm; rRNA transcription; ribonucleoside binding; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter,PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;,1.00E-101,CHOYP_BRAFLDRAFT_223894.1.1,,,,,,,RPA2_HUMAN,Homo sapiens (Human),"embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp132724_c0_seq5,1672,43.6603,0.40415366,121,444,,7.00E-108,Q61578,"NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase)","NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase)",GO:0008203; GO:0005743; GO:0005759; GO:0016491,cholesterol metabolic process; mitochondrial inner membrane; mitochondrial matrix; oxidoreductase activity,PF07992;,1.00E-75,CHOYP_BRAFLDRAFT_88012.1.1,,,,,,,ADRO_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; NADPH oxidation [GO:0070995] comp132731_c0_seq1,1295,34.8263,0.43460791,788,565,,5.00E-66,Q0VCN3,Intraflagellar transport protein 27 homolog (IFT27) (Putative GTP-binding protein RAY-like) (Rab-like protein 4),Intraflagellar transport protein 27 homolog (IFT27) (Putative GTP-binding protein RAY-like) (Rab-like protein 4),GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF00071;,5.00E-66,CHOYP_LOC100376429.1.1,4.00E-115,ruditapes2_lrc3671,,,,,IFT27_BOVIN,Bos taurus (Bovine),intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224] comp132735_c0_seq1,420,48.3333,0.90396765,9,26,,9.00E-32,Q15935,Zinc finger protein 77 (ZNFpT1),Zinc finger protein 77 (ZNFpT1),GO:0003677; GO:0005737; GO:0046872; GO:0005730; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF77_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132735_c1_seq1,1096,42.7007,0.92210179,24,63,,2.00E-27,Q9H7X3,Zinc finger protein 696,Zinc finger protein 696,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN696_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132735_c1_seq2,793,43.0013,1.00455625,0,3,,2.00E-30,Q8IYN0,Zinc finger protein 100,Zinc finger protein 100,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN100_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132736_c0_seq2,700,40.1429,0.4800368,0,0,,3.00E-19,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp132740_c0_seq1,1892,43.2875,0.48640571,10,3,,0,A0M8U1,Suppressor of tumorigenicity 7 protein homolog,Suppressor of tumorigenicity 7 protein homolog,GO:0016021,integral to membrane,PF04184;,0,CHOYP_ST7.1.1,,,,,,,ST7_CHICK,Gallus gallus (Chicken), comp132740_c0_seq2,1904,43.2248,0.48462972,3,0,,0,A7S641,Protein ST7 homolog,Protein ST7 homolog,GO:0016021,integral to membrane,PF04184;,,,,,,,,,ST7_NEMVE,Nematostella vectensis (Starlet sea anemone), comp132745_c0_seq1,721,46.4632,0.71130546,0,0,,7.00E-06,Q9D8T7,"SRA stem-loop-interacting RNA-binding protein, mitochondrial","SRA stem-loop-interacting RNA-binding protein, mitochondrial",GO:0003723; GO:0005739; GO:0000961; GO:0000166; GO:0005634; GO:0006355; GO:0030529; GO:0006351,"RNA binding; mitochondrion; negative regulation of mitochondrial RNA catabolic process; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF00076;,,,,,,,,,SLIRP_MOUSE,Mus musculus (Mouse),"mitochondrion morphogenesis [GO:0070584]; negative regulation of mitochondrial RNA catabolic process [GO:0000961]; regulation of transcription, DNA-templated [GO:0006355]; single fertilization [GO:0007338]; spermatid development [GO:0007286]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]" comp132745_c0_seq2,2046,43.4506,0.56768263,271,56,,3.00E-114,Q5R5W2,TAR DNA-binding protein 43 (TDP-43),TAR DNA-binding protein 43 (TDP-43),GO:0003677; GO:0003723; GO:0008380; GO:0006397; GO:0000166; GO:0005634; GO:0006355; GO:0006351,"DNA binding; RNA binding; RNA splicing; mRNA processing; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00076;,7.00E-111,CHOYP_LOC656201.1.1,,,,,,,TADBP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp132750_c0_seq1,2082,31.172,0.39597006,287,1892,,,,,,,,,,,1.00E-17,ruditapes2_c3350,,,,,,, comp132751_c0_seq1,1448,37.7072,0.40178591,4,23,,9.00E-112,P27600,Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12),Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12),GO:0031752; GO:0031683; GO:0005525; GO:0003924; GO:0007266; GO:0007188; GO:0031526; GO:0030154; GO:0042733; GO:0005834; GO:0001701; GO:0007243; GO:0046872; GO:0032006; GO:0008360; GO:0010762; GO:0032434; GO:0042493; GO:0004871,D5 dopamine receptor binding; G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity; Rho protein signal transduction; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; brush border membrane; cell differentiation; embryonic digit morphogenesis; heterotrimeric G-protein complex; in utero embryonic development; intracellular protein kinase cascade; metal ion binding; regulation of TOR signaling cascade; regulation of cell shape; regulation of fibroblast migration; regulation of proteasomal ubiquitin-dependent protein catabolic process; response to drug; signal transducer activity,PF00503;,2.00E-108,CHOYP_LOC100371005.2.2,,,,,,,GNA12_MOUSE,Mus musculus (Mouse),adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to drug [GO:0042493]; Rho protein signal transduction [GO:0007266] comp132751_c0_seq5,1239,39.4673,0.42141064,0,0,,9.00E-113,P27600,Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12),Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12),GO:0031752; GO:0031683; GO:0005525; GO:0003924; GO:0007266; GO:0007188; GO:0031526; GO:0030154; GO:0042733; GO:0005834; GO:0001701; GO:0007243; GO:0046872; GO:0032006; GO:0008360; GO:0010762; GO:0032434; GO:0042493; GO:0004871,D5 dopamine receptor binding; G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity; Rho protein signal transduction; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; brush border membrane; cell differentiation; embryonic digit morphogenesis; heterotrimeric G-protein complex; in utero embryonic development; intracellular protein kinase cascade; metal ion binding; regulation of TOR signaling cascade; regulation of cell shape; regulation of fibroblast migration; regulation of proteasomal ubiquitin-dependent protein catabolic process; response to drug; signal transducer activity,PF00503;,5.00E-110,CHOYP_LOC100371005.1.2,,,,,,,GNA12_MOUSE,Mus musculus (Mouse),adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to drug [GO:0042493]; Rho protein signal transduction [GO:0007266] comp132756_c0_seq1,845,47.1006,0.58269003,65,62,,4.00E-85,O14578,Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0048699; GO:0035556; GO:0046872; GO:0007091; GO:0007067; GO:0000070; GO:0050774; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; generation of neurons; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitosis; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,5.00E-64,CHOYP_CIT.1.2,,,,,,,CTRO_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467] comp132759_c0_seq1,1529,36.1674,0.54144408,1816,8540,,1.00E-113,Q6DJE4,Cleavage and polyadenylation specificity factor subunit 5,Cleavage and polyadenylation specificity factor subunit 5,GO:0017091; GO:0016787; GO:0003729; GO:0005849; GO:0006378; GO:0042382,AU-rich element binding; hydrolase activity; mRNA binding; mRNA cleavage factor complex; mRNA polyadenylation; paraspeckles,PF13869;,2.00E-123,CHOYP_CPSF5.2.2,8.00E-144,ruditapes_c9001,,,,,CPSF5_XENLA,Xenopus laevis (African clawed frog),mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397] comp132771_c0_seq1,1556,41.2596,0.54440582,60,26,,0,Q8CHB8,Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 5),Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 5),GO:0005813; GO:0005929; GO:0005737; GO:0009566; GO:0016874; GO:0005932; GO:0005634; GO:0018095; GO:0007288; GO:0030317; GO:0006351,"centrosome; cilium; cytoplasm; fertilization; ligase activity; microtubule basal body; nucleus; protein polyglutamylation; sperm axoneme assembly; sperm motility; transcription, DNA-dependent",PF03133;,0,CHOYP_contig_044341,,,,,,,TTLL5_MOUSE,Mus musculus (Mouse),"fertilization [GO:0009566]; protein polyglutamylation [GO:0018095]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]" comp132771_c0_seq2,482,47.3029,0.59629886,0,0,,5.00E-19,Q6EEF3,Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),GO:0006464; GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0005634; GO:0006351,"cellular protein modification process; cilium; cytoplasm; ligase activity; microtubule basal body; nucleus; transcription, DNA-dependent",PF03133;,,,,,,,,,TTLL5_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),"cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]" comp132771_c0_seq4,473,48.8372,0.60541217,0,0,,,,,,,,,4.00E-36,CHOYP_TTLL5.1.1,,,,,,,,, comp132771_c0_seq5,1247,47.4739,0.60404533,0,0,,,,,,,,,3.00E-18,CHOYP_LOC100177360.1.1,,,,,,,,, comp132773_c0_seq1,783,41.6347,0.82672526,8,32,,8.00E-20,Q5XM24,Autocrine proliferation repressor protein A (PhoPQ-activated pathogenicity-related protein),Autocrine proliferation repressor protein A (PhoPQ-activated pathogenicity-related protein),GO:0007049; GO:0005576; GO:0005622; GO:0008285; GO:0043234; GO:0031157; GO:0030435,cell cycle; extracellular region; intracellular; negative regulation of cell proliferation; protein complex; regulation of aggregate size involved in sorocarp development; sporulation resulting in formation of a cellular spore,PF10142;,,,,,,,,,APRA_DICDI,Dictyostelium discoideum (Slime mold),cell cycle [GO:0007049]; negative chemotaxis [GO:0050919]; negative regulation of asexual reproduction [GO:1903665]; protein localization to plasma membrane [GO:0072659]; regulation of aggregate size involved in sorocarp development [GO:0031157]; sporulation resulting in formation of a cellular spore [GO:0030435] comp132773_c0_seq2,423,40.8983,0.9074422,0,0,,,,,,,,,1.00E-22,CHOYP_BRAFLDRAFT_121045.1.1,,,,,,,,, comp132777_c0_seq8,1742,34.2135,0.43356753,22,0,,7.00E-109,Q5PQ44,Uncharacterized protein C4orf22 homolog,Uncharacterized protein C4orf22 homolog,,,PF14713;,,,,,,,,,CD022_XENLA,Xenopus laevis (African clawed frog), comp132777_c0_seq9,1911,33.9089,0.34713154,0,0,,3.00E-108,Q5PQ44,Uncharacterized protein C4orf22 homolog,Uncharacterized protein C4orf22 homolog,,,PF14713;,1.00E-120,CHOYP_BRAFLDRAFT_122572.1.1,2.00E-127,ruditapes2_c1920,,,,,CD022_XENLA,Xenopus laevis (African clawed frog), comp132778_c0_seq1,525,29.3333,0.56307073,696,1244,,,,,,,,,,,4.00E-35,ruditapes_c10561,,,,,,, comp132782_c0_seq1,846,39.5981,0.55735985,1082,3167,,2.00E-17,P82912,"28S ribosomal protein S11, mitochondrial (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2)","28S ribosomal protein S11, mitochondrial (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2)",GO:0042769; GO:0005763; GO:0003735; GO:0006412,"DNA damage response, detection of DNA damage; mitochondrial small ribosomal subunit; structural constituent of ribosome; translation",PF00411;,,,,,,,,,RT11_HUMAN,Homo sapiens (Human),"DNA damage response, detection of DNA damage [GO:0042769]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]" comp132784_c0_seq1,1004,34.2629,0.81999061,477,905,,1.00E-13,Q8CP18,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ_STAES,Staphylococcus epidermidis (strain ATCC 12228),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp132785_c1_seq1,666,44.1441,0.55769357,50,63,,1.00E-43,Q14094,Cyclin-I,Cyclin-I,GO:0007283,spermatogenesis,PF00134;,5.00E-24,CHOYP_BRAFLDRAFT_265991.1.1,,,,,,,CCNI_HUMAN,Homo sapiens (Human),regulation of cell cycle [GO:0051726]; spermatogenesis [GO:0007283] comp132793_c2_seq1,699,37.3391,0.58077635,198,329,,2.00E-39,O00142,"Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)","Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)",GO:0005524; GO:0004137; GO:0046092; GO:0009262; GO:0006264; GO:0005743; GO:0005759; GO:0016773; GO:0006206; GO:0043097; GO:0004797; GO:0046104,"ATP binding; deoxycytidine kinase activity; deoxycytidine metabolic process; deoxyribonucleotide metabolic process; mitochondrial DNA replication; mitochondrial inner membrane; mitochondrial matrix; phosphotransferase activity, alcohol group as acceptor; pyrimidine nucleobase metabolic process; pyrimidine nucleoside salvage; thymidine kinase activity; thymidine metabolic process",PF01712;,2.00E-22,CHOYP_TK2.1.1,,,,,,,KITM_HUMAN,Homo sapiens (Human),deoxycytidine metabolic process [GO:0046092]; DNA biosynthetic process [GO:0071897]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside salvage [GO:0043097]; thymidine metabolic process [GO:0046104] comp132795_c1_seq1,835,45.509,0.55733413,16,10,,5.00E-61,Q54F23,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog),,,,4.00E-128,CHOYP_MROH1.1.1,,,,,,,HTR7A_DICDI,Dictyostelium discoideum (Slime mold), comp132796_c0_seq1,1270,38.2677,0.35898907,136,307,,3.00E-41,Q9W704,RPA-interacting protein A (RPA-interacting protein alpha) (XRIPalpha),RPA-interacting protein A (RPA-interacting protein alpha) (XRIPalpha),GO:0046872; GO:0005634,metal ion binding; nucleus,PF14768;PF14767;PF14766;,2.00E-21,CHOYP_BRAFLDRAFT_212934.1.1,,,,,,,RIPA_XENLA,Xenopus laevis (African clawed frog), comp132798_c0_seq1,697,44.7633,0.59135124,82,1166,,2.00E-62,Q4KLC4,Neuroguidin-A (EIF4E-binding protein A),Neuroguidin-A (EIF4E-binding protein A),GO:0005737; GO:0005634; GO:0006417,cytoplasm; nucleus; regulation of translation,PF04000;,2.00E-30,CHOYP_LOC100374036.1.1,8.00E-83,ruditapes2_c1824,,,,,NGDNA_XENLA,Xenopus laevis (African clawed frog),regulation of translation [GO:0006417] comp132809_c0_seq1,1601,30.4809,0.46269131,754,5859,,,,,,,,,,,1.00E-21,ruditapes_c3012,,,,,,, comp132809_c2_seq1,668,38.3234,0.63884788,72,869,,4.00E-43,Q6X4M2,15 kDa selenoprotein,15 kDa selenoprotein,GO:0005788; GO:0008430,endoplasmic reticulum lumen; selenium binding,PF08806;,2.00E-11,CHOYP_SEP15.1.1,,,,,,,SEP15_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri), comp132810_c0_seq1,849,40.1649,0.48436566,149,186,,3.00E-07,Q8CHY6,Transcriptional repressor p66 alpha (GATA zinc finger domain-containing protein 2A),Transcriptional repressor p66 alpha (GATA zinc finger domain-containing protein 2A),GO:0016581; GO:0021506; GO:0001568; GO:0010172; GO:0001701; GO:0046872; GO:0045892; GO:0001842; GO:0016607; GO:0012501; GO:0030674; GO:0006351,"NuRD complex; anterior neuropore closure; blood vessel development; embryonic body morphogenesis; in utero embryonic development; metal ion binding; negative regulation of transcription, DNA-dependent; neural fold formation; nuclear speck; programmed cell death; protein binding, bridging; transcription, DNA-dependent",PF16563;,,,,,,,,,P66A_MOUSE,Mus musculus (Mouse),"anterior neuropore closure [GO:0021506]; blood vessel development [GO:0001568]; DNA methylation [GO:0006306]; embryonic body morphogenesis [GO:0010172]; in utero embryonic development [GO:0001701]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural fold formation [GO:0001842]; programmed cell death [GO:0012501]; transcription, DNA-templated [GO:0006351]" comp132810_c1_seq1,1113,42.3181,0.54274828,135,205,,2.00E-37,Q8VHR5,Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68),Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68),GO:0016607; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nuclear speck; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00320;PF16563;,3.00E-105,CHOYP_P66A.1.1,,,,,,,P66B_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; DNA methylation [GO:0006306]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp132811_c0_seq1,863,43.6848,0.99729864,53,148,,7.00E-07,Q8BR93,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,7.00E-11,CHOYP_contig_018031,,,,,,,HARB1_MOUSE,Mus musculus (Mouse), comp132813_c0_seq1,1274,37.5981,0.55344581,55,133,,2.00E-13,Q99068,Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Gp330-binding 45 kDa protein) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP),Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Gp330-binding 45 kDa protein) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP),GO:0009986; GO:1900116; GO:0005576; GO:0008201; GO:1900222; GO:0032091; GO:0010916; GO:0005886; GO:0048237; GO:0031982,cell surface; extracellular negative regulation of signal transduction; extracellular region; heparin binding; negative regulation of beta-amyloid clearance; negative regulation of protein binding; negative regulation of very-low-density lipoprotein particle clearance; plasma membrane; rough endoplasmic reticulum lumen; vesicle,PF06401;PF06400;,,,,,,,,,AMRP_RAT,Rattus norvegicus (Rat),extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of beta-amyloid clearance [GO:1900222]; negative regulation of protein binding [GO:0032091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916] comp132815_c0_seq1,960,34.1667,0.72894227,967,8119,,2.00E-25,Q93725,NEDD8 (Neddylin) (Protein NED-8) (Ubiquitin-like protein Nedd8),NEDD8 (Neddylin) (Protein NED-8) (Ubiquitin-like protein Nedd8),GO:0005737; GO:0007275; GO:0005634,cytoplasm; multicellular organismal development; nucleus,PF00240;,3.00E-54,CHOYP_LOC100114789.1.1,,,,,,,NEDD8_CAEEL,Caenorhabditis elegans,"multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; positive regulation of apoptotic process [GO:0043065]" comp132816_c2_seq4,1712,47.2547,0.62823982,0,3,,2.00E-15,A8MT70,Zinc finger B-box domain-containing protein 1,Zinc finger B-box domain-containing protein 1,GO:0005622; GO:0008270,intracellular; zinc ion binding,PF00643;,,,,,,,,,ZBBX_HUMAN,Homo sapiens (Human), comp132816_c3_seq1,273,42.4908,0.54745989,9,15,,,,,,,,,7.00E-18,CHOYP_LOC100892912.1.1,,,,,,,,, comp132821_c0_seq1,1128,39.8936,0.75556359,111,101,,1.00E-119,Q6IMM1,DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein),DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein),GO:0005525; GO:0005739; GO:0007264,GTP binding; mitochondrion; small GTPase mediated signal transduction,PF00226;PF00071;,2.00E-108,CHOYP_BRAFLDRAFT_213951.1.1,,,4.00E-86,AM856856.p.cg.6,7,,DJC27_CHICK,Gallus gallus (Chicken),positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of MAPK export from nucleus [GO:0071701]; small GTPase mediated signal transduction [GO:0007264] comp132823_c2_seq2,1185,41.2658,0.32120271,0,0,,4.00E-84,Q9N1Q4,Large neutral amino acids transporter small subunit 2 (4F2-LC5) (L-type amino acid transporter 2) (Solute carrier family 7 member 8),Large neutral amino acids transporter small subunit 2 (4F2-LC5) (L-type amino acid transporter 2) (Solute carrier family 7 member 8),GO:0015179; GO:0015171; GO:0016323; GO:0005737; GO:0016021; GO:0015804; GO:0015101; GO:0042605; GO:0019534,L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity; basolateral plasma membrane; cytoplasm; integral to membrane; neutral amino acid transport; organic cation transmembrane transporter activity; peptide antigen binding; toxin transporter activity,PF13520;,5.00E-103,CHOYP_LOC100377923.1.1,,,,,,,LAT2_RABIT,Oryctolagus cuniculus (Rabbit),neutral amino acid transport [GO:0015804] comp132825_c0_seq1,597,39.3635,0.58654156,6,28,,4.00E-61,Q9TS33,Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),GO:0005509; GO:0006874; GO:0071318; GO:0071313; GO:0071277; GO:0071286; GO:0016021; GO:0006936; GO:0051289; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; cellular response to ATP; cellular response to caffeine; cellular response to calcium ion; cellular response to magnesium ion; integral to membrane; muscle contraction; protein homotetramerization; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,4.00E-113,CHOYP_LOC100643070.1.1,,,,,,,RYR3_RABIT,Oryctolagus cuniculus (Rabbit),calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; muscle contraction [GO:0006936]; protein homotetramerization [GO:0051289] comp132826_c0_seq1,781,41.3572,0.59072934,13,250,,2.00E-117,Q9H2P9,Diphthine synthase (EC 2.1.1.98) (Diphthamide biosynthesis methyltransferase),Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase),GO:0004164; GO:0017183,diphthine synthase activity; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF00590;,,,,,,,,,DPH5_HUMAN,Homo sapiens (Human),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp132826_c0_seq2,897,41.1371,0.53788626,18,331,,8.00E-100,Q6C1E0,Diphthine synthase (EC 2.1.1.98) (Diphthamide biosynthesis methyltransferase),Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase),GO:0005737; GO:0004164; GO:0017183,cytoplasm; diphthine synthase activity; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF00590;,2.00E-87,CHOYP_LOC577892.2.2,,,,,,,DPH5_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; regulation of cytoplasmic translation [GO:2000765] comp132827_c0_seq1,3649,41.9841,0.66095293,0,0,,0,O77819,"Rho-associated protein kinase 1 (EC 2.7.11.1) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEBM1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (cAMP-dependent protein kinase ROCK-I) (CePKA) (p160 ROCK-1) (p160ROCK)","Rho-associated protein kinase 1 (EC 2.7.11.1) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEBM1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (cAMP-dependent protein kinase ROCK-I) (CePKA) (p160 ROCK-1) (p160ROCK)",GO:0005524; GO:0000139; GO:0006915; GO:0032059; GO:0005814; GO:0005856; GO:0035556; GO:0030027; GO:0046872; GO:0005543; GO:0005886; GO:0004674; GO:0001726,ATP binding; Golgi membrane; apoptotic process; bleb; centriole; cytoskeleton; intracellular signal transduction; lamellipodium; metal ion binding; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; ruffle,PF00069;PF08912;,,,,,,,,,ROCK1_RABIT,Oryctolagus cuniculus (Rabbit),actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; myoblast migration [GO:0051451]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of establishment of cell polarity [GO:2000114]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266] comp132827_c0_seq2,1903,41.4609,0.70061839,0,0,,3.00E-120,Q80UW5,Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0031252; GO:0005813; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0004674; GO:0005083,ATP binding; actin cytoskeleton reorganization; cell leading edge; centrosome; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF00069;PF00433;,0,CHOYP_ROCK2.1.1,,,,,,,MRCKG_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp132827_c0_seq3,3634,41.9648,0.66370455,0,0,,0,Q28021,"Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)","Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)",GO:0005524; GO:0030036; GO:0005829; GO:0035556; GO:0046872; GO:0005815; GO:0005634; GO:0005543; GO:0005886; GO:0004672; GO:0004674,ATP binding; actin cytoskeleton organization; cytosol; intracellular signal transduction; metal ion binding; microtubule organizing center; nucleus; phospholipid binding; plasma membrane; protein kinase activity; protein serine/threonine kinase activity,PF00069;PF08912;,1.00E-34,CHOYP_GEK.1.1,,,,,,,ROCK2_BOVIN,Bos taurus (Bovine),actin cytoskeleton organization [GO:0030036]; positive regulation of centrosome duplication [GO:0010825]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of circadian rhythm [GO:0042752]; Rho protein signal transduction [GO:0007266]; rhythmic process [GO:0048511]; smooth muscle contraction [GO:0006939] comp132827_c0_seq4,1918,41.5016,0.69509315,0,0,,0,P70335,"Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)","Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)",GO:0005524; GO:0000139; GO:0007266; GO:0030036; GO:0003383; GO:0006915; GO:0032059; GO:0032060; GO:0005814; GO:0005856; GO:0030027; GO:0050901; GO:0022614; GO:0046872; GO:0016525; GO:0043524; GO:0005543; GO:0005886; GO:0004674; GO:0032970; GO:0045616; GO:0001726,ATP binding; Golgi membrane; Rho protein signal transduction; actin cytoskeleton organization; apical constriction; apoptotic process; bleb; bleb assembly; centriole; cytoskeleton; lamellipodium; leukocyte tethering or rolling; membrane to membrane docking; metal ion binding; negative regulation of angiogenesis; negative regulation of neuron apoptotic process; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; regulation of actin filament-based process; regulation of keratinocyte differentiation; ruffle,PF00069;PF08912;,0,CHOYP_ROCK2.1.1,,,,,,,ROCK1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; apical constriction [GO:0003383]; apoptotic process [GO:0006915]; bleb assembly [GO:0032060]; cortical actin cytoskeleton organization [GO:0030866]; establishment of protein localization to plasma membrane [GO:0090002]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; myoblast migration [GO:0051451]; negative regulation of angiogenesis [GO:0016525]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament-based process [GO:0032970]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of keratinocyte differentiation [GO:0045616]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266] comp132827_c1_seq1,1151,39.3571,0.51689465,48,49,,6.00E-48,P61584,"Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) (Fragment)","Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) (Fragment)",GO:0005524; GO:0000139; GO:0006915; GO:0032059; GO:0005814; GO:0005856; GO:0035556; GO:0030027; GO:0046872; GO:0005543; GO:0005886; GO:0004674; GO:0001726,ATP binding; Golgi membrane; apoptotic process; bleb; centriole; cytoskeleton; intracellular signal transduction; lamellipodium; metal ion binding; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; ruffle,PF08912;,,,,,,,,,ROCK1_PANTR,Pan troglodytes (Chimpanzee),apoptotic process [GO:0006915]; myoblast migration [GO:0051451]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of establishment of cell polarity [GO:2000114]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266] comp132828_c0_seq1,911,40.3952,0.35044824,28,185,,8.00E-90,Q9UGM6,"Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)","Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)",GO:0005524; GO:0005759; GO:0006418; GO:0004830; GO:0006436; GO:0001570,ATP binding; mitochondrial matrix; tRNA aminoacylation for protein translation; tryptophan-tRNA ligase activity; tryptophanyl-tRNA aminoacylation; vasculogenesis,PF00579;,,,,,,,,,SYWM_HUMAN,Homo sapiens (Human),tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570] comp132831_c0_seq1,1991,39.0256,0.29911959,2798,11614,,0,Q4R4R0,26S protease regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2),26S protease regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2),GO:0005524; GO:0016887; GO:0000932; GO:0005634; GO:0022624; GO:0006511,ATP binding; ATPase activity; cytoplasmic mRNA processing body; nucleus; proteasome accessory complex; ubiquitin-dependent protein catabolic process,PF00004;,0,CHOYP_PRS7.1.1,0,ruditapes_c14899,,,,,PRS7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),ubiquitin-dependent protein catabolic process [GO:0006511] comp132832_c2_seq1,1112,48.6511,0.70299942,22,177,,3.00E-32,P49796,Regulator of G-protein signaling 3 (RGP3) (RGS3),Regulator of G-protein signaling 3 (RGP3) (RGS3),GO:0005096; GO:0005829; GO:0000188; GO:0005634; GO:0005886; GO:0008277; GO:0038032,GTPase activator activity; cytosol; inactivation of MAPK activity; nucleus; plasma membrane; regulation of G-protein coupled receptor protein signaling pathway; termination of G-protein coupled receptor signaling pathway,PF00168;PF00595;PF00615;,2.00E-39,CHOYP_PHUM_PHUM492360.1.1,,,,,,,RGS3_HUMAN,Homo sapiens (Human),inactivation of MAPK activity [GO:0000188]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp132832_c2_seq2,307,49.5114,0.6511697,3,33,,,,,,,,,7.00E-12,CHOYP_PHUM_PHUM492360.1.1,,,,,,,,, comp132837_c0_seq2,1615,42.8483,0.41101481,30,107,,7.00E-24,Q5VNW5,Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL2 (EC 3.1.1.n2) (Isoprenylcysteine methylesterase-like protein 2),Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL2 (EC 3.1.1.n2) (Isoprenylcysteine methylesterase-like protein 2),GO:0000139; GO:0004091; GO:0005789; GO:0016021,Golgi membrane; carboxylesterase activity; endoplasmic reticulum membrane; integral to membrane,PF00135;,,,,,,,,,IMCL2_ORYSJ,Oryza sativa subsp. japonica (Rice), comp132838_c0_seq1,1111,35.9136,0.51265281,96,497,,7.00E-24,Q5VUE5,Uncharacterized protein C1orf53,Uncharacterized protein C1orf53,,,,,,,,,,,,CA053_HUMAN,Homo sapiens (Human), comp132840_c0_seq2,899,39.822,0.99819498,13,607,,2.00E-16,A1ZA47,PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),GO:0030018; GO:0015629; GO:0051371; GO:0005927; GO:0030239; GO:0001952; GO:0008270,Z disc; actin cytoskeleton; muscle alpha-actinin binding; muscle tendon junction; myofibril assembly; regulation of cell-matrix adhesion; zinc ion binding,PF15936;PF00412;PF00595;,2.00E-11,CHOYP_SMP_006860.2.1.4,,,,,,,ZASP_DROME,Drosophila melanogaster (Fruit fly),muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952] comp132844_c0_seq1,2046,46.3832,0.80195003,15,13179,female>male,3.00E-18,Q9SQH9,Ammonium transporter 1 member 3 (AtAMT1;3),Ammonium transporter 1 member 3 (AtAMT1;3),GO:0008519; GO:0016021; GO:0080181; GO:0010311; GO:0005886,ammonium transmembrane transporter activity; integral to membrane; lateral root branching; lateral root formation; plasma membrane,PF00909;,,,,,,,,,AMT13_ARATH,Arabidopsis thaliana (Mouse-ear cress),ammonium transport [GO:0015696]; lateral root branching [GO:0080181]; lateral root formation [GO:0010311]; nitrogen utilization [GO:0019740]; organic cation transport [GO:0015695] comp132845_c0_seq1,1033,42.6912,0.39130471,19,101,,7.00E-49,Q8N3Y1,F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29),F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29),GO:0031467; GO:0005794; GO:0007030; GO:0019005; GO:0060716; GO:0048471; GO:0050775; GO:0060712,Cul7-RING ubiquitin ligase complex; Golgi apparatus; Golgi organization; SCF ubiquitin ligase complex; labyrinthine layer blood vessel development; perinuclear region of cytoplasm; positive regulation of dendrite morphogenesis; spongiotrophoblast layer development,PF12937;,4.00E-15,CHOYP_LOC100371688.1.1,,,,,,,FBXW8_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712] comp132848_c1_seq1,1621,43.4917,0.3684451,62,26,,8.00E-121,O70157,DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha),DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0016605; GO:0005694; GO:0005654; GO:0008270,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; PML body; chromosome; nucleoplasm; zinc ion binding,PF01131;PF01751;PF01396;PF06839;,2.00E-58,CHOYP_TOP3A.1.2,,,,,,,TOP3A_MOUSE,Mus musculus (Mouse),DNA topological change [GO:0006265] comp132850_c0_seq3,701,37.2325,0.94820489,0,90,,1.00E-19,Q6XQH0,"Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2)","Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2)",GO:0032580; GO:0009058; GO:0001733; GO:0016021,Golgi cisterna membrane; biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane,PF06990;,,,,,,,,,G3ST2_MOUSE,Mus musculus (Mouse),glycolipid biosynthetic process [GO:0009247]; glycoprotein biosynthetic process [GO:0009101]; sulfation [GO:0051923] comp132853_c0_seq1,1010,48.1188,0.39403221,2,25,,1.00E-137,Q2M389,WASH complex subunit 7,WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP),GO:0071203; GO:0016197; GO:0005768,WASH complex; endosomal transport; endosome,PF14746;PF14744;PF14745;,,,,,,,,,WASH7_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031] comp132853_c0_seq2,1004,48.008,0.36347233,10,86,,2.00E-137,Q2M389,WASH complex subunit 7,WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP),GO:0071203; GO:0016197; GO:0005768,WASH complex; endosomal transport; endosome,PF14746;PF14744;PF14745;,4.00E-148,CHOYP_LOC100372619.2.2,,,,,,,WASH7_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031] comp132854_c4_seq3,2854,43.2025,0.39738543,18,5,,0,A1A4J6,Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1) (ATPase class II type 9B),Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1) (ATPase class II type 9B),GO:0005524; GO:0005794; GO:0019829; GO:0072600; GO:0016021; GO:0000287; GO:0048471; GO:0004012; GO:0005802,ATP binding; Golgi apparatus; cation-transporting ATPase activity; establishment of protein localization to Golgi; integral to membrane; magnesium ion binding; perinuclear region of cytoplasm; phospholipid-translocating ATPase activity; trans-Golgi network,PF00122;PF16212;PF16209;,0,CHOYP_ATP9B.1.2,,,,,,,ATP9B_BOVIN,Bos taurus (Bovine),"endocytosis [GO:0006897]; establishment of protein localization to Golgi [GO:0072600]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp132854_c4_seq4,1708,41.2763,0.37736772,0,0,,1.00E-49,O54827,Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPase class V type 10A) (P-locus fat-associated ATPase),Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPase class V type 10A) (P-locus fat-associated ATPase) (P4-ATPase flippase complex alpha subunit ATP10A),GO:0005524; GO:0019829; GO:0005789; GO:0016021; GO:0000287; GO:0004012; GO:0005886,ATP binding; cation-transporting ATPase activity; endoplasmic reticulum membrane; integral to membrane; magnesium ion binding; phospholipid-translocating ATPase activity; plasma membrane,PF00122;PF16212;PF16209;,,,,,,,,,AT10A_MOUSE,Mus musculus (Mouse), comp132855_c1_seq6,238,32.7731,0.80472801,4,54,,,,,,,,,7.00E-11,CHOYP_contig_028648,,,,,,,,, comp132855_c1_seq8,527,33.9658,0.1987959,9,125,,,,,,,,,6.00E-16,CHOYP_contig_054017,,,,,,,,, comp132859_c0_seq1,880,36.7045,0.85567321,6,340,,3.00E-36,P26624,Glutathione S-transferase class-mu 28 kDa isozyme (GST 28) (EC 2.5.1.18) (Sj28 antigen) (Sj28GST) (Fragment),Glutathione S-transferase class-mu 28 kDa isozyme (GST 28) (EC 2.5.1.18) (Sj28 antigen) (Sj28GST) (Fragment),GO:0004364,glutathione transferase activity,PF14497;PF02798;,,,,,,,,,GST28_SCHJA,Schistosoma japonicum (Blood fluke), comp132859_c0_seq3,982,38.2892,0.89427243,0,35,,5.00E-28,P18426,S-crystallin SL11 (Major lens polypeptide),S-crystallin SL11 (Major lens polypeptide),GO:0005212,structural constituent of eye lens,PF14497;PF02798;,,,,,,,,,SCR11_OMMSL,Nototodarus sloanii (Wellington flying squid) (Ommastrephes sloanei), comp132865_c0_seq1,235,37.0213,0.25106838,2,0,,2.00E-06,P52922,Leukotriene A-4 hydrolase homolog (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase),Leukotriene A-4 hydrolase homolog (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase),GO:0004177; GO:0005737; GO:0004301; GO:0019370; GO:0004463; GO:0008237; GO:0043171; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; epoxide hydrolase activity; leukotriene biosynthetic process; leukotriene-A4 hydrolase activity; metallopeptidase activity; peptide catabolic process; proteolysis; zinc ion binding,PF09127;PF01433;,,,,,,,,,LKHA4_DICDI,Dictyostelium discoideum (Slime mold),leukotriene biosynthetic process [GO:0019370]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp132866_c1_seq1,490,29.3878,0.09589884,114,266,,,,,,,,,,,5.00E-20,ruditapes_c17033,,,,,,, comp132869_c1_seq1,703,48.0797,0.5485013,3,12,,8.00E-24,Q9NZQ8,Transient receptor potential cation channel subfamily M member 5 (Long transient receptor potential channel 5) (LTrpC-5) (LTrpC5) (MLSN1- and TRP-related gene 1 protein),Transient receptor potential cation channel subfamily M member 5 (Long transient receptor potential channel 5) (LTrpC-5) (LTrpC5) (MLSN1- and TRP-related gene 1 protein),GO:0005227; GO:0016021; GO:0005216; GO:0005886; GO:0005267; GO:0005272; GO:0005244,calcium activated cation channel activity; integral to membrane; ion channel activity; plasma membrane; potassium channel activity; sodium channel activity; voltage-gated ion channel activity,PF00520;,,,,,,,,,TRPM5_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; sensory perception of taste [GO:0050909] comp132869_c1_seq2,819,48.3516,0.61639844,6,8,,3.00E-112,Q9HCF6,Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2),Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2),GO:0005262; GO:0005261; GO:0016021,calcium channel activity; cation channel activity; integral to membrane,PF00520;PF16519;,7.00E-169,CHOYP_TRPM3.1.7,,,,,,,TRPM3_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; detection of temperature stimulus [GO:0016048]; protein tetramerization [GO:0051262]; sensory perception of temperature stimulus [GO:0050951] comp132869_c2_seq1,1288,46.118,0.67415592,34,5,,7.00E-62,Q7Z4N2,Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1),Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1),GO:0007216; GO:0005262; GO:0060402; GO:0071482; GO:0005887; GO:0035841; GO:0046548; GO:0007601,G-protein coupled glutamate receptor signaling pathway; calcium channel activity; calcium ion transport into cytosol; cellular response to light stimulus; integral to plasma membrane; new growing cell tip; retinal rod cell development; visual perception,PF00520;PF16519;,,,,,,,,,TRPM1_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cellular response to light stimulus [GO:0071482]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; protein tetramerization [GO:0051262]; retinal rod cell development [GO:0046548]; transport [GO:0006810]; visual perception [GO:0007601] comp132869_c2_seq3,816,47.0588,0.64907091,0,0,,8.00E-73,A8DYE2,Transient receptor potential cation channel trpm,"Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)",GO:0005261; GO:0034703; GO:0016049; GO:0070838; GO:0010960; GO:0046873; GO:0007005; GO:0055069,cation channel activity; cation channel complex; cell growth; divalent metal ion transport; magnesium ion homeostasis; metal ion transmembrane transporter activity; mitochondrion organization; zinc ion homeostasis,PF00520;PF16519;,1.00E-33,CHOYP_TRPM3.2.7,,,,,,,TRPCG_DROME,Drosophila melanogaster (Fruit fly),cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069] comp132872_c0_seq1,1702,46.7098,0.48501953,10,0,,1.00E-177,Q92621,Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205),Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205),GO:0005975; GO:0019221; GO:0015758; GO:0051028; GO:0007077; GO:0031965; GO:0034399; GO:0005643; GO:0051292; GO:0000059; GO:0010827; GO:0044281; GO:0017056; GO:0055085; GO:0016032,"carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore complex assembly; protein import into nucleus, docking; regulation of glucose transport; small molecule metabolic process; structural constituent of nuclear pore; transmembrane transport; viral process",PF11894;,,,,,,,,,NU205_HUMAN,Homo sapiens (Human),"gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]" comp132872_c0_seq2,1630,46.2577,0.47050853,8,0,,,,,,,,,3.00E-26,CHOYP_NUP205.1.1,,,,,,,,, comp132875_c0_seq1,859,42.142,0.71507857,0,0,,3.00E-26,A2PYL6,Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II),Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II),GO:0005524; GO:0006096; GO:0004396,ATP binding; glycolysis; hexokinase activity,PF00349;PF03727;,,,,,,,,,HXK2_HORSE,Equus caballus (Horse),cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318] comp132875_c0_seq5,1334,43.8531,0.7670259,0,0,,4.00E-85,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,,,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp132879_c0_seq3,2297,35.8729,0.41555162,7,21,,1.00E-151,Q54I79,Centractin (Actin-related protein A),Centractin (Actin-related protein A),GO:0005524; GO:0005813; GO:0005737; GO:0016192,ATP binding; centrosome; cytoplasm; vesicle-mediated transport,PF00022;,,,,,,,,,ACTY_DICDI,Dictyostelium discoideum (Slime mold),vesicle-mediated transport [GO:0016192] comp132879_c0_seq4,1550,37.9355,0.45935975,0,0,,0,P85515,Alpha-centractin (Centractin),Alpha-centractin (Centractin),GO:0005524; GO:0005813; GO:0005737,ATP binding; centrosome; cytoplasm,PF00022;,0,CHOYP_ACTZ.1.1,8.00E-18,ruditapes_c18995,,,,,ACTZ_RAT,Rattus norvegicus (Rat), comp132880_c1_seq1,915,37.377,0.51713128,36,423,,1.00E-34,Q3BCR0,Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase),Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase),GO:0005737; GO:0008119,cytoplasm; thiopurine S-methyltransferase activity,PF05724;,,,,,,,,,TPMT_PANLE,Panthera leo (Lion), comp132880_c2_seq1,814,42.3833,0.95959911,7,171,,5.00E-73,Q9BHM6,Octopine dehydrogenase (OcDH) (EC 1.5.1.11),Octopine dehydrogenase (OcDH) (EC 1.5.1.11),GO:0047830; GO:0051287; GO:0005737; GO:0046168; GO:0016616,"D-octopine dehydrogenase activity; NAD binding; cytoplasm; glycerol-3-phosphate catabolic process; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF02317;,,,,,,,,,OCDH_PECMA,Pecten maximus (King scallop) (Pilgrim's clam), comp132883_c0_seq1,278,42.0863,0.34745157,3,39,,6.00E-09,P59991,Keratin-associated protein 12-2 (High sulfur keratin-associated protein 12.2) (Keratin-associated protein 12.2),Keratin-associated protein 12-2 (High sulfur keratin-associated protein 12.2) (Keratin-associated protein 12.2),GO:0045095,keratin filament,PF05287;,,,,,,,,,KR122_HUMAN,Homo sapiens (Human), comp132883_c1_seq1,2091,42.3242,0.48355294,87,200,,7.00E-17,Q5T5J6,Transcriptional protein SWT1,Transcriptional protein SWT1,,,PF13638;,,,,,,,,,SWT1_HUMAN,Homo sapiens (Human), comp132885_c0_seq1,516,43.2171,0.62661838,0,96,,4.00E-09,P31421,Metabotropic glutamate receptor 2 (mGluR2),Metabotropic glutamate receptor 2 (mGluR2),GO:0030424; GO:0005246; GO:0030054; GO:0030425; GO:0014047; GO:0001641; GO:0005887; GO:0005622; GO:0042734; GO:0046928; GO:0051966,"axon; calcium channel regulator activity; cell junction; dendrite; glutamate secretion; group II metabotropic glutamate receptor activity; integral to plasma membrane; intracellular; presynaptic membrane; regulation of neurotransmitter secretion; regulation of synaptic transmission, glutamatergic",PF00003;PF01094;PF07562;,,,,,,,,,GRM2_RAT,Rattus norvegicus (Rat),"glutamate secretion [GO:0014047]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]" comp132885_c1_seq1,1793,40.3793,0.63534757,0,0,,3.00E-06,Q2YDG0,G-protein coupled receptor family C group 5 member C,G-protein coupled receptor family C group 5 member C,GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00003;,,,,,,,,,GPC5C_BOVIN,Bos taurus (Bovine), comp132885_c1_seq2,2133,41.3502,0.61815092,0,68,,3.00E-06,Q2YDG0,G-protein coupled receptor family C group 5 member C,G-protein coupled receptor family C group 5 member C,GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00003;,1.00E-121,CHOYP_GRM1.2.2,,,,,,,GPC5C_BOVIN,Bos taurus (Bovine), comp132887_c0_seq1,1075,38.6047,0.50630573,37,58,,5.00E-33,P34230,Peroxisomal long-chain fatty acid import protein 1 (Peroxisomal ABC transporter 2),Peroxisomal long-chain fatty acid import protein 1 (Peroxisomal ABC transporter 2),GO:0005524; GO:0042626; GO:0006635; GO:1902001; GO:0005779; GO:0042758; GO:0005325; GO:0042760,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; fatty acid beta-oxidation; fatty acid transmembrane transport; integral to peroxisomal membrane; long-chain fatty acid catabolic process; peroxisomal fatty-acyl-CoA transporter activity; very long-chain fatty acid catabolic process",PF06472;PF00005;,,,,,,,,,PXA2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),fatty acid beta-oxidation [GO:0006635]; fatty acid transmembrane transport [GO:1902001]; fatty-acyl-CoA transport [GO:0015916]; long-chain fatty acid catabolic process [GO:0042758]; peroxisomal long-chain fatty acid import [GO:0015910]; very long-chain fatty acid catabolic process [GO:0042760] comp132887_c2_seq1,1277,42.0517,0.39114128,76,127,,5.00E-149,Q9UBJ2,ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR),ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR),GO:0005524; GO:0006200; GO:0042626; GO:0005829; GO:0006635; GO:0016021; GO:0005739; GO:0005778; GO:0032000; GO:0042803; GO:0055085; GO:0042760,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; cytosol; fatty acid beta-oxidation; integral to membrane; mitochondrion; peroxisomal membrane; positive regulation of fatty acid beta-oxidation; protein homodimerization activity; transmembrane transport; very long-chain fatty acid catabolic process",PF06472;PF00005;,2.00E-102,CHOYP_LOC100373129.1.1,,,,,,,ABCD2_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation [GO:0006635]; positive regulation of fatty acid beta-oxidation [GO:0032000]; transmembrane transport [GO:0055085]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] comp132889_c0_seq2,1479,41.5822,0.59957383,85,256,,2.00E-119,Q9UMX1,Suppressor of fused homolog (SUFUH),Suppressor of fused homolog (SUFUH),GO:0005737; GO:0042994; GO:0001947; GO:0045668; GO:2000059; GO:0043433; GO:0045879; GO:1901621; GO:0042992; GO:0000122; GO:0001843; GO:0005634; GO:0072372; GO:0006508; GO:0004871; GO:0001501; GO:0043588; GO:0021776; GO:0021775; GO:0003714; GO:0008134,cytoplasm; cytoplasmic sequestering of transcription factor; heart looping; negative regulation of osteoblast differentiation; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of smoothened signaling pathway; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; negative regulation of transcription factor import into nucleus; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; primary cilium; proteolysis; signal transducer activity; skeletal system development; skin development; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; smoothened signaling pathway involved in ventral spinal cord interneuron specification; transcription corepressor activity; transcription factor binding,PF05076;PF12470;,2.00E-103,CHOYP_LOC100313743.2.2,3.00E-105,ruditapes_c17103,,,,,SUFU_HUMAN,Homo sapiens (Human),"aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart looping [GO:0001947]; multicellular organism development [GO:0007275]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skin development [GO:0043588]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; ventricular septum development [GO:0003281]" comp132889_c0_seq3,222,50.4505,0.29198628,0,0,,,,,,,,,2.00E-18,CHOYP_LOC100313743.1.2,,,,,,,,, comp132890_c0_seq1,1162,39.5009,0.66944291,0,0,,2.00E-20,P98170,E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),GO:0016055; GO:0055070; GO:0043027; GO:0005829; GO:0097193; GO:0043066; GO:0005634; GO:0090263; GO:0030510; GO:0042127; GO:0050727; GO:0045088; GO:0070424; GO:0006974; GO:0004842; GO:0008270,Wnt receptor signaling pathway; copper ion homeostasis; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytosol; intrinsic apoptotic signaling pathway; negative regulation of apoptotic process; nucleus; positive regulation of canonical Wnt receptor signaling pathway; regulation of BMP signaling pathway; regulation of cell proliferation; regulation of inflammatory response; regulation of innate immune response; regulation of nucleotide-binding oligomerization domain containing signaling pathway; response to DNA damage stimulus; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,XIAP_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; copper ion homeostasis [GO:0055070]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; regulation of BMP signaling pathway [GO:0030510]; regulation of cell proliferation [GO:0042127]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; Wnt signaling pathway [GO:0016055] comp132890_c0_seq2,1209,38.2134,0.68594151,0,0,,7.00E-21,Q96P09,Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis),Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis),GO:0005829; GO:0043154; GO:0043524; GO:0005634; GO:0048471; GO:0043234; GO:0008270,cytosol; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of neuron apoptotic process; nucleus; perinuclear region of cytoplasm; protein complex; zinc ion binding,PF00653;,,,,,,,,,BIRC8_HUMAN,Homo sapiens (Human),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; positive regulation of canonical Wnt signaling pathway [GO:0090263] comp132890_c0_seq3,312,44.2308,0.75422462,0,0,,3.00E-17,O62640,Putative inhibitor of apoptosis,Putative inhibitor of apoptosis,GO:0006915; GO:0005737; GO:0070266; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0016567; GO:0042981; GO:0004842; GO:0008270,apoptotic process; cytoplasm; necroptosis; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; protein ubiquitination; regulation of apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,PIAP_PIG,Sus scrofa (Pig),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121] comp132890_c0_seq4,359,39.2758,0.8185264,0,0,,2.00E-14,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp132894_c1_seq1,2372,44.0556,0.63483157,54,51,,2.00E-43,A4IIJ3,Protein KIBRA (WW domain-containing protein 1),Protein KIBRA (WW domain-containing protein 1),GO:0005737; GO:0005634; GO:0006355; GO:0006351,"cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00168;PF00397;,2.00E-67,CHOYP_LOC100879690.1.1,,,,,,,KIBRA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132894_c1_seq2,1541,44.4517,0.65961734,0,0,,3.00E-08,P24506,Synaptotagmin-B (Synaptic vesicle protein O-p65-B),Synaptotagmin-B (Synaptic vesicle protein O-p65-B),GO:0030054; GO:0016021; GO:0046872; GO:0030672; GO:0005215,cell junction; integral to membrane; metal ion binding; synaptic vesicle membrane; transporter activity,PF00168;,,,,,,,,,SY62_DISOM,Diplobatis ommata (Ocellated electric ray) (Discopyge ommata),neurotransmitter secretion [GO:0007269] comp132894_c2_seq1,1690,45.6213,0.57629037,69,54,,9.00E-44,Q6NXJ0,Protein WWC2 (WW domain-containing protein 2),Protein WWC2 (WW domain-containing protein 2),,,PF00397;,,,,,,,,,WWC2_MOUSE,Mus musculus (Mouse),negative regulation of hippo signaling [GO:0035331]; negative regulation of organ growth [GO:0046621]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp132898_c0_seq1,345,46.087,0.71991642,5,18,,6.00E-20,P25773,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Progesterone-dependent protein) (PDP) (Fragment),Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Progesterone-dependent protein) (PDP) (Fragment),GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF00112;,,,,,,,,,CATL1_FELCA,Felis catus (Cat) (Felis silvestris catus),proteolysis involved in cellular protein catabolic process [GO:0051603] comp132898_c0_seq2,345,45.5072,0.86070375,0,0,,2.00E-12,P05993,Cysteine proteinase (EC 3.4.22.-) (Clone PLBPC13) (Fragment),Cysteine proteinase (EC 3.4.22.-) (Clone PLBPC13) (Fragment),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF00112;,1.00E-10,CHOYP_LOC763308.1.3,2.00E-11,ruditapes_lrc16077,,,,,PAPA5_CARPA,Carica papaya (Papaya), comp132898_c0_seq3,752,45.6117,0.89612535,43,204,,4.00E-64,Q9GKL8,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08246;PF00112;,1.00E-20,CHOYP_NEMVEDRAFT_V1G180651.1.2,,,,,,,CATL1_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),viral entry into host cell [GO:0046718] comp132904_c0_seq1,1219,39.2125,1.14601663,7,414,,,,,,,,,,,2.00E-11,ruditapes_c21986,,,,,,, comp132906_c0_seq1,2210,40.905,0.49602918,137,226,,3.00E-42,B6ELU0,tRNA 2-thiocytidine biosynthesis protein TtcA,tRNA 2-thiocytidine biosynthesis protein TtcA,GO:0005524; GO:0005737; GO:0008033,ATP binding; cytoplasm; tRNA processing,PF01171;,1.00E-113,CHOYP_LOC100377968.1.1,,,,,,,TTCA_ALISL,Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)),tRNA processing [GO:0008033] comp132906_c2_seq1,787,46.2516,0.38482497,32,44,,8.00E-15,Q9K7A0,Probable cysteine desulfurase (EC 2.8.1.7),Probable cysteine desulfurase (EC 2.8.1.7),GO:0031071; GO:0006534; GO:0030170,cysteine desulfurase activity; cysteine metabolic process; pyridoxal phosphate binding,PF00266;,,,,,,,,,CSD_BACHD,Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125),cysteine metabolic process [GO:0006534] comp132913_c0_seq2,1854,35.5448,0.25912654,4,61,,3.00E-26,Q9NUP1,Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog),Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog),GO:0031083; GO:0008089; GO:0048490; GO:0032438; GO:0050885; GO:0031175; GO:0070527; GO:0006892,BLOC-1 complex; anterograde axon cargo transport; anterograde synaptic vesicle transport; melanosome organization; neuromuscular process controlling balance; neuron projection development; platelet aggregation; post-Golgi vesicle-mediated transport,,,,,,,,,,CNO_HUMAN,Homo sapiens (Human),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular transport [GO:0046907]; melanosome organization [GO:0032438]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; platelet aggregation [GO:0070527] comp132914_c0_seq1,3037,33.7175,0.58042902,1680,15340,,1.00E-18,Q5ZK63,Activated RNA polymerase II transcriptional coactivator p15 (SUB1 homolog),Activated RNA polymerase II transcriptional coactivator p15 (SUB1 homolog),GO:0003677; GO:0005634; GO:0006355; GO:0003713; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent",PF02229;,2.00E-18,CHOYP_LOC100900939.1.1,4.00E-31,ruditapes2_c3131,,,,,TCP4_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132920_c0_seq3,937,42.0491,0.65138963,45,2,,9.00E-41,O95428,Papilin,Papilin,GO:0005604; GO:0004222; GO:0004867; GO:0008270,basement membrane; metalloendopeptidase activity; serine-type endopeptidase inhibitor activity; zinc ion binding,PF05986;PF07679;PF00014;PF08686;PF00090;,,,,,,,,,PPN_HUMAN,Homo sapiens (Human), comp132920_c1_seq1,211,51.6588,0.66714785,21,0,,4.00E-12,P0C5H6,Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A),Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A),GO:0030154; GO:0030054; GO:0016021; GO:0007399; GO:0005886; GO:0045202,cell differentiation; cell junction; integral to membrane; nervous system development; plasma membrane; synapse,PF00041;PF07679;,,,,,,,,,TUTLA_RAT,Rattus norvegicus (Rat),dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] comp132920_c2_seq1,1104,47.2826,0.49271741,82,35,,2.00E-09,Q9HCB6,Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor),Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor),GO:0007155; GO:0005615; GO:0005578,cell adhesion; extracellular space; proteinaceous extracellular matrix,PF02014;PF06468;PF00090;,,,,,,,,,SPON1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; protein O-linked fucosylation [GO:0036066] comp132921_c0_seq1,531,46.1394,0.99466165,434,331,,,,,,,,,2.00E-41,CHOYP_RAB7A.2.2,1.00E-47,ruditapes2_c272,,,,,,, comp132922_c0_seq1,608,49.6711,0.88397486,12,81,,,,,,,,,1.00E-24,CHOYP_BRAFLDRAFT_84643.1.1,6.00E-21,ruditapes_c26815,,,,,,, comp132922_c0_seq2,1183,46.7456,0.8984032,78,456,,5.00E-10,Q93RV9,Ectoine hydroxylase (EC 1.17.-.-),Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase),GO:0016725,"oxidoreductase activity, acting on CH or CH2 groups",PF05721;,,,7.00E-55,ruditapes_c11809,,,,,ECTD_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),ectoine catabolic process [GO:0042400] comp132926_c0_seq2,420,48.3333,0.77963405,1,78,,2.00E-25,Q24048,Sodium/potassium-transporting ATPase subunit beta-2 (Protein nervana 2) (Sodium/potassium-dependent ATPase subunit beta-2),Sodium/potassium-transporting ATPase subunit beta-2 (Protein nervana 2) (Sodium/potassium-dependent ATPase subunit beta-2),GO:0006812; GO:0061343; GO:0060857; GO:0006813; GO:0035158; GO:0035159; GO:0007605; GO:0005918; GO:0019991; GO:0006814; GO:0005890,"cation transport; cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; potassium ion transport; regulation of tube diameter, open tracheal system; regulation of tube length, open tracheal system; sensory perception of sound; septate junction; septate junction assembly; sodium ion transport; sodium:potassium-exchanging ATPase complex",PF00287;,,,,,,,,,ATPB2_DROME,Drosophila melanogaster (Fruit fly),"cation transport [GO:0006812]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; open tracheal system development [GO:0007424]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; regulation of tube size, open tracheal system [GO:0035151]; sensory perception of sound [GO:0007605]; septate junction assembly [GO:0019991]" comp132929_c0_seq1,246,43.9024,0.67788427,13,8,,5.00E-24,P15396,Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],GO:0035529; GO:0005576; GO:0006955; GO:0016021; GO:0046872; GO:0003676; GO:0004528; GO:0030247; GO:0005044,NADH pyrophosphatase activity; extracellular region; immune response; integral to membrane; metal ion binding; nucleic acid binding; phosphodiesterase I activity; polysaccharide binding; scavenger receptor activity,PF01223;PF01663;PF01033;,6.00E-12,CHOYP_ENPP3.1.1,,,,,,,ENPP3_BOVIN,Bos taurus (Bovine),immune response [GO:0006955] comp132929_c1_seq2,1001,43.956,1.12922727,33,122,,1.00E-17,P06802,Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Lymphocyte antigen 41) (Ly-41) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Lymphocyte antigen 41) (Ly-41) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],GO:0035529; GO:0016323; GO:0031214; GO:0046849; GO:0009986; GO:0005615; GO:0006955; GO:0016021; GO:0046872; GO:0045599; GO:0030279; GO:0003676; GO:0004528; GO:0005886; GO:0030247; GO:0005044,NADH pyrophosphatase activity; basolateral plasma membrane; biomineral tissue development; bone remodeling; cell surface; extracellular space; immune response; integral to membrane; metal ion binding; negative regulation of fat cell differentiation; negative regulation of ossification; nucleic acid binding; phosphodiesterase I activity; plasma membrane; polysaccharide binding; scavenger receptor activity,PF01223;PF01663;PF01033;,,,,,,,,,ENPP1_MOUSE,Mus musculus (Mouse),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; biomineral tissue development [GO:0031214]; bone remodeling [GO:0046849]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to insulin stimulus [GO:0032869]; generation of precursor metabolites and energy [GO:0006091]; immune response [GO:0006955]; inorganic diphosphate transport [GO:0030505]; negative regulation of cell growth [GO:0030308]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of ossification [GO:0030279]; negative regulation of protein autophosphorylation [GO:0031953]; nucleoside triphosphate catabolic process [GO:0009143]; phosphate-containing compound metabolic process [GO:0006796]; sequestering of triglyceride [GO:0030730] comp132931_c1_seq1,768,34.6354,0.53254938,3,5,,3.00E-54,P10078,Zinc finger protein 28 (Zfp-28) (Protein mKR5),Zinc finger protein 28 (Zfp-28) (Protein mKR5),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP28_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132931_c1_seq2,757,36.9881,0.89021806,6,77,,1.00E-49,A2T812,Zinc finger protein 287,Zinc finger protein 287,GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZN287_PONPY,Pongo pygmaeus (Bornean orangutan),"transcription, DNA-templated [GO:0006351]" comp132931_c1_seq4,565,36.2832,0.92218039,1,11,,4.00E-22,P58334,Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Dopamine receptor-regulating factor) (Transcription factor BTEB4),Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Dopamine receptor-regulating factor) (Transcription factor BTEB4),GO:0003677; GO:0007212; GO:0046872; GO:0005634; GO:0006357; GO:0003700; GO:0006351,"DNA binding; dopamine receptor signaling pathway; metal ion binding; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,KLF16_MOUSE,Mus musculus (Mouse),"dopamine receptor signaling pathway [GO:0007212]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp132931_c1_seq5,571,34.1506,0.6153203,0,0,,6.00E-25,O15156,Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK),Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK),GO:0003677; GO:0030154; GO:0007398; GO:0046872; GO:0007275; GO:0005634; GO:0045944; GO:0043370; GO:0043376; GO:0003700; GO:0006366,"DNA binding; cell differentiation; ectoderm development; metal ion binding; multicellular organismal development; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of CD4-positive, alpha-beta T cell differentiation; regulation of CD8-positive, alpha-beta T cell differentiation; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter",PF00651;,,,,,,,,,ZBT7B_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; multicellular organism development [GO:0007275]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp132931_c2_seq1,1512,34.5899,0.60860847,6,20,,5.00E-52,Q8N9F8,Zinc finger protein 454,Zinc finger protein 454,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN454_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132931_c2_seq2,734,36.921,0.56217325,0,0,,4.00E-33,P51815,Zinc finger protein 75D (Zinc finger protein 75) (Zinc finger protein 82),Zinc finger protein 75D (Zinc finger protein 75) (Zinc finger protein 82),GO:0003677; GO:0005634; GO:0006355; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF02023;PF00096;,,,,,,,,,ZN75D_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp132931_c2_seq3,833,36.9748,0.59906285,1,12,,7.00E-56,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp132931_c2_seq4,1900,41.0526,0.58014625,0,0,,3.00E-08,Q9QX96,Sal-like protein 2 (Spalt-like protein 2) (Zinc finger protein Spalt-2) (Sal-2) (mSal-2),Sal-like protein 2 (Spalt-like protein 2) (Zinc finger protein Spalt-2) (Sal-2) (mSal-2),GO:0003677; GO:0046872; GO:0000122; GO:0021915; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; neural tube development; nucleus; transcription, DNA-dependent",PF13912;,,,,,,,,,SALL2_MOUSE,Mus musculus (Mouse),"eye development [GO:0001654]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube development [GO:0021915]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp132931_c2_seq5,1413,34.4657,0.63351286,0,0,,1.00E-25,Q966L8,Transcription factor che-1 (Abnormal chemotaxis protein 1),Transcription factor che-1 (Abnormal chemotaxis protein 1),GO:0006935; GO:0046872; GO:0030182; GO:0005634; GO:0045944; GO:0050920; GO:0043565; GO:0006351,"chemotaxis; metal ion binding; neuron differentiation; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of chemotaxis; sequence-specific DNA binding; transcription, DNA-dependent",PF00096;,,,,,,,,,CHE1_CAEEL,Caenorhabditis elegans,"chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; neuron differentiation [GO:0030182]; positive regulation of chemotaxis [GO:0050921]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of chemotaxis [GO:0050920]; response to alkaline pH [GO:0010446]; response to inorganic substance [GO:0010035]; response to lithium ion [GO:0010226]; response to magnesium ion [GO:0032026]; response to methionine [GO:1904640]; response to salt [GO:1902074]; transcription, DNA-templated [GO:0006351]" comp132931_c2_seq7,2226,38.3648,0.52836581,31,68,,2.00E-08,Q3SWU4,Zinc finger and BTB domain-containing protein 44 (BTB/POZ domain-containing protein 15),Zinc finger and BTB domain-containing protein 44 (BTB/POZ domain-containing protein 15),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT44_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp132936_c0_seq1,826,37.4092,0.66892393,2865,6006,,5.00E-23,P52503,"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)","NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)",GO:0072358; GO:0006631; GO:0005747; GO:0005739; GO:0070584; GO:0035264; GO:0010259; GO:0006936; GO:0061458; GO:0022904,cardiovascular system development; fatty acid metabolic process; mitochondrial respiratory chain complex I; mitochondrion; mitochondrion morphogenesis; multicellular organism growth; multicellular organismal aging; muscle contraction; reproductive system development; respiratory electron transport chain,PF10276;,,,1.00E-56,ruditapes_lrc35703,,,,,NDUS6_MOUSE,Mus musculus (Mouse),"cardiovascular system development [GO:0072358]; fatty acid metabolic process [GO:0006631]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrion morphogenesis [GO:0070584]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; muscle contraction [GO:0006936]; reproductive system development [GO:0061458]; respiratory electron transport chain [GO:0022904]" comp132945_c1_seq1,1908,37.7883,0.3379022,4,70,,1.00E-83,Q500W7,GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M) (Protein PEANUT 1),GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M) (Protein PEANUT 1),GO:0006506; GO:0005789; GO:0016021; GO:0016758,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring hexosyl groups",PF05007;,,,,,,,,,PIGM_ARATH,Arabidopsis thaliana (Mouse-ear cress),GPI anchor biosynthetic process [GO:0006506] comp132945_c1_seq2,1814,37.9824,0.3058646,0,7,,4.00E-123,Q66IJ4,GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M),GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M),GO:0006506; GO:0005789; GO:0016021; GO:0016758,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring hexosyl groups",PF05007;,,,,,,,,,PIGM_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),GPI anchor biosynthetic process [GO:0006506] comp132945_c1_seq3,1057,36.8969,0.30645698,0,5,,3.00E-34,Q5EA10,GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M),GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M),GO:0006506; GO:0005789; GO:0016021; GO:0016758,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring hexosyl groups",PF05007;,5.00E-20,CHOYP_PIGM.1.1,,,,,,,PIGM_BOVIN,Bos taurus (Bovine),GPI anchor biosynthetic process [GO:0006506] comp132945_c2_seq1,903,37.0986,0.19424175,12,63,,2.00E-35,Q08602,Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha),Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha),GO:0004663; GO:0018344; GO:0008270,Rab geranylgeranyltransferase activity; protein geranylgeranylation; zinc ion binding,PF01239;PF07711;,,,,,,,,,PGTA_RAT,Rattus norvegicus (Rat),protein geranylgeranylation [GO:0018344] comp132945_c3_seq1,400,44,0.36549708,1,35,,,,,,,,,8.00E-13,CHOYP_PGTA.1.1,,,,,,,,, comp132946_c1_seq3,2239,40.7325,0.31306785,0,0,,1.00E-10,Q66H33,Uncharacterized protein C3orf38 homolog,Uncharacterized protein C3orf38 homolog,GO:0006915,apoptotic process,PF15008;,,,,,,,,,CC038_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915] comp132946_c1_seq8,624,40.0641,0.4401138,0,0,,7.00E-12,Q66H33,Uncharacterized protein C3orf38 homolog,Uncharacterized protein C3orf38 homolog,GO:0006915,apoptotic process,PF15008;,,,,,,,,,CC038_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915] comp132947_c0_seq1,2667,38.0577,0.5954551,1269,3059,,0,P26038,Moesin (Membrane-organizing extension spike protein),Moesin (Membrane-organizing extension spike protein),GO:0045177; GO:0016324; GO:0016323; GO:0005737; GO:0005856; GO:0070062; GO:0019898; GO:0030175; GO:0007159; GO:0050900; GO:0022614; GO:0005902; GO:0031528; GO:0005730; GO:0005886; GO:2000401; GO:0005200; GO:0001931,apical part of cell; apical plasma membrane; basolateral plasma membrane; cytoplasm; cytoskeleton; extracellular vesicular exosome; extrinsic to membrane; filopodium; leukocyte cell-cell adhesion; leukocyte migration; membrane to membrane docking; microvillus; microvillus membrane; nucleolus; plasma membrane; regulation of lymphocyte migration; structural constituent of cytoskeleton; uropod,PF00769;PF09380;PF00373;PF09379;,0,CHOYP_RADI.1.2,,,,,,,MOES_HUMAN,Homo sapiens (Human),cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; movement of cell or subcellular component [GO:0006928]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115] comp132948_c2_seq1,1786,41.6573,0.45867907,154,602,,1.00E-64,Q9UHJ6,Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein),Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein),GO:0005524; GO:0035963; GO:0071353; GO:0071222; GO:0005737; GO:0009052; GO:0050727; GO:0043030; GO:0050277,"ATP binding; cellular response to interleukin-13; cellular response to interleukin-4; cellular response to lipopolysaccharide; cytoplasm; pentose-phosphate shunt, non-oxidative branch; regulation of inflammatory response; regulation of macrophage activation; sedoheptulokinase activity",PF00370;,,,,,,,,,SHPK_HUMAN,Homo sapiens (Human),"carbohydrate metabolic process [GO:0005975]; cellular response to interleukin-13 [GO:0035963]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; phosphorylation [GO:0016310]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030]" comp132950_c0_seq1,475,42.7368,0.74448033,0,0,,8.00E-33,P34100,Developmentally-regulated protein kinase 1 (EC 2.7.11.1),Developmentally-regulated protein kinase 1 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PKD1_DICDI,Dictyostelium discoideum (Slime mold), comp132950_c0_seq2,1127,40.4614,0.52711348,90,218,,5.00E-26,P49071,MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (EC 2.7.11.1),MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (EC 2.7.11.1),GO:0005524; GO:0007155; GO:0045793; GO:0004674; GO:0046328; GO:0008360; GO:0009651,ATP binding; cell adhesion; positive regulation of cell size; protein serine/threonine kinase activity; regulation of JNK cascade; regulation of cell shape; response to salt stress,PF00069;,,,,,,,,,MAPK2_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell size [GO:0045793]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of JNK cascade [GO:0046328]; response to salt stress [GO:0009651] comp132950_c0_seq3,1124,42.1708,0.72259549,46,75,,0,Q15418,Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1),Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1),GO:0005524; GO:0002755; GO:0035666; GO:0007411; GO:0007049; GO:0043027; GO:0005829; GO:0045087; GO:0000287; GO:0043066; GO:0048011; GO:0005654; GO:0045597; GO:0030307; GO:2000491; GO:0045944; GO:0004674; GO:0043620; GO:0043555; GO:0005819; GO:0051403; GO:0007268; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124,ATP binding; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; axon guidance; cell cycle; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytosol; innate immune response; magnesium ion binding; negative regulation of apoptotic process; neurotrophin TRK receptor signaling pathway; nucleoplasm; positive regulation of cell differentiation; positive regulation of cell growth; positive regulation of hepatic stellate cell activation; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; regulation of DNA-dependent transcription in response to stress; regulation of translation in response to stress; spindle; stress-activated MAPK cascade; synaptic transmission; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway,PF00069;PF00433;,0,CHOYP_KS6A1.1.1,,,,,,,KS6A1_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; hepatocyte proliferation [GO:0072574]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; signal transduction [GO:0007165] comp132950_c1_seq1,441,40.5896,0.51408897,11,0,,5.00E-09,P08018,MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4),MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4),GO:0005524; GO:0004708; GO:0000208; GO:0017196; GO:0031416; GO:0007015; GO:0000169; GO:0005935; GO:0005934; GO:0034605; GO:0006972; GO:0004596; GO:0018108; GO:0004674; GO:0004713; GO:0046677,ATP binding; MAP kinase kinase activity; MAPK import into nucleus involved in osmosensory signaling pathway; N-terminal peptidyl-methionine acetylation; NatB complex; actin filament organization; activation of MAPK activity involved in osmosensory signaling pathway; cellular bud neck; cellular bud tip; cellular response to heat; hyperosmotic response; peptide alpha-N-acetyltransferase activity; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; response to antibiotic,PF00069;,,,,,,,,,PBS2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin filament organization [GO:0007015]; activation of MAPK activity involved in osmosensory signaling pathway [GO:0000169]; cellular response to heat [GO:0034605]; hyperosmotic response [GO:0006972]; MAPK import into nucleus involved in osmosensory signaling pathway [GO:0000208]; mitotic cell cycle [GO:0000278]; N-terminal peptidyl-methionine acetylation [GO:0017196]; osmosensory signaling pathway [GO:0007231]; protein phosphorylation [GO:0006468]; response to antibiotic [GO:0046677] comp132950_c1_seq2,414,40.3382,0.49552528,7,48,,2.00E-28,Q2LZZ7,Serine/threonine-protein kinase tricorner (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like),Serine/threonine-protein kinase tricorner (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like),GO:0005524; GO:0005737; GO:0007243; GO:0046872; GO:0005634; GO:0004674; GO:0050773,ATP binding; cytoplasm; intracellular protein kinase cascade; metal ion binding; nucleus; protein serine/threonine kinase activity; regulation of dendrite development,PF00069;,,,,,,,,,TRC_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165] comp132955_c0_seq1,877,38.0844,0.4478292,0,0,,5.00E-48,P83094,Stromal interaction molecule homolog,Stromal interaction molecule homolog,GO:0032237; GO:0005509; GO:0048763; GO:0022416; GO:0005513; GO:0005789; GO:0007476; GO:0016021; GO:0005886; GO:0051533; GO:0015279; GO:0002115,activation of store-operated calcium channel activity; calcium ion binding; calcium-induced calcium release activity; chaeta development; detection of calcium ion; endoplasmic reticulum membrane; imaginal disc-derived wing morphogenesis; integral to membrane; plasma membrane; positive regulation of NFAT protein import into nucleus; store-operated calcium channel activity; store-operated calcium entry,PF07647;PF16533;,,,,,,,,,STIM_DROME,Drosophila melanogaster (Fruit fly),activation of store-operated calcium channel activity [GO:0032237]; cell adhesion [GO:0007155]; chaeta development [GO:0022416]; detection of calcium ion [GO:0005513]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of NFAT protein import into nucleus [GO:0051533]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac conduction [GO:1903779]; store-operated calcium entry [GO:0002115] comp132955_c0_seq3,2293,42.041,0.505673,9,0,,2.00E-62,P83094,Stromal interaction molecule homolog,Stromal interaction molecule homolog,GO:0032237; GO:0005509; GO:0048763; GO:0022416; GO:0005513; GO:0005789; GO:0007476; GO:0016021; GO:0005886; GO:0051533; GO:0015279; GO:0002115,activation of store-operated calcium channel activity; calcium ion binding; calcium-induced calcium release activity; chaeta development; detection of calcium ion; endoplasmic reticulum membrane; imaginal disc-derived wing morphogenesis; integral to membrane; plasma membrane; positive regulation of NFAT protein import into nucleus; store-operated calcium channel activity; store-operated calcium entry,PF07647;PF16533;,,,,,,,,,STIM_DROME,Drosophila melanogaster (Fruit fly),activation of store-operated calcium channel activity [GO:0032237]; cell adhesion [GO:0007155]; chaeta development [GO:0022416]; detection of calcium ion [GO:0005513]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of NFAT protein import into nucleus [GO:0051533]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac conduction [GO:1903779]; store-operated calcium entry [GO:0002115] comp132955_c0_seq4,2236,41.9499,0.50096214,1,21,,,,,,,,,,,4.00E-23,ruditapes_c9583,,,,,,, comp132957_c0_seq1,638,36.3636,0.33886447,52,139,,1.00E-36,Q5ZI57,Trafficking protein particle complex subunit 3,Trafficking protein particle complex subunit 3,GO:0006888; GO:0000139; GO:0030008; GO:0005829; GO:0005783,ER to Golgi vesicle-mediated transport; Golgi membrane; TRAPP complex; cytosol; endoplasmic reticulum,PF04051;,1.00E-38,CHOYP_TPPC3.1.1,,,,,,,TPPC3_CHICK,Gallus gallus (Chicken),ER to Golgi vesicle-mediated transport [GO:0006888] comp132959_c0_seq1,585,36.4103,0.84958566,307,868,,1.00E-10,P56277,Cx9C motif-containing protein 4 (Mature T-cell proliferation 1 neighbor protein) (Mature T-cell proliferation-1 type A) (MTCP-1 type A) (Protein p8 MTCP-1) (p8MTCP1),Cx9C motif-containing protein 4 (Mature T-cell proliferation 1 neighbor protein) (Mature T-cell proliferation-1 type A) (MTCP-1 type A) (Protein p8 MTCP-1) (p8MTCP1),GO:0008283; GO:0005739,cell proliferation; mitochondrion,PF08991;,,,,,,,,,MTCNB_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283] comp132963_c0_seq1,914,42.8884,0.45639559,31,50,,9.00E-53,Q63276,Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Kan-1) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Kan-1) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),GO:0016410; GO:0006637; GO:0006699; GO:0002152; GO:0004091; GO:0005829; GO:0006631; GO:0047963; GO:0006544; GO:0001889; GO:0052815; GO:0031100; GO:0016290; GO:0005777; GO:0019530; GO:0052817,N-acyltransferase activity; acyl-CoA metabolic process; bile acid biosynthetic process; bile acid conjugation; carboxylesterase activity; cytosol; fatty acid metabolic process; glycine N-choloyltransferase activity; glycine metabolic process; liver development; medium-chain acyl-CoA hydrolase activity; organ regeneration; palmitoyl-CoA hydrolase activity; peroxisome; taurine metabolic process; very long chain acyl-CoA hydrolase activity,PF08840;PF04775;,,,,,,,,,BAAT_RAT,Rattus norvegicus (Rat),acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530] comp132963_c0_seq2,940,42.9787,0.60495086,18,96,,3.00E-57,Q91X34,Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),GO:0016410; GO:0006637; GO:0006699; GO:0002152; GO:0008206; GO:0004091; GO:0005829; GO:0006631; GO:0047963; GO:0006544; GO:0001889; GO:0052815; GO:0031100; GO:0016290; GO:0005777; GO:0019530; GO:0052817,N-acyltransferase activity; acyl-CoA metabolic process; bile acid biosynthetic process; bile acid conjugation; bile acid metabolic process; carboxylesterase activity; cytosol; fatty acid metabolic process; glycine N-choloyltransferase activity; glycine metabolic process; liver development; medium-chain acyl-CoA hydrolase activity; organ regeneration; palmitoyl-CoA hydrolase activity; peroxisome; taurine metabolic process; very long chain acyl-CoA hydrolase activity,PF08840;PF04775;,,,,,,,,,BAAT_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530] comp132971_c0_seq2,1412,45.0425,0.77451703,21,238,,3.00E-180,Q7SXK5,Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1),Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1),GO:0005737; GO:0019556; GO:0019557; GO:0050480; GO:0046872,cytoplasm; histidine catabolic process to glutamate and formamide; histidine catabolic process to glutamate and formate; imidazolonepropionase activity; metal ion binding,PF01979;,2.00E-53,CHOYP_LOC100371597.1.1,,,,,,,HUTI_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] comp132978_c0_seq2,479,43.8413,0.61759299,3,0,,7.00E-50,Q60695,Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1),Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1),GO:0005085; GO:0005622; GO:0051056; GO:0007264,guanyl-nucleotide exchange factor activity; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00617;PF00618;,5.00E-54,CHOYP_LOC655842.1.1,,,,,,,RGL1_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp132978_c0_seq3,434,42.6267,0.61412091,0,0,,3.00E-07,P26674,Protein ste6,Protein ste6,GO:0005829; GO:0005085; GO:0000750; GO:0051056; GO:0007264,cytosol; guanyl-nucleotide exchange factor activity; pheromone-dependent signal transduction involved in conjugation with cellular fusion; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00617;PF00618;PF00018;,,,,,,,,,STE6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),conjugation with cellular fusion [GO:0000747]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; small GTPase mediated signal transduction [GO:0007264] comp132978_c0_seq4,270,42.2222,0.6724658,0,0,,2.00E-22,Q12967,Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF),Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF),GO:0007265; GO:0005829; GO:0005085; GO:0048011; GO:0051056; GO:0005083,Ras protein signal transduction; cytosol; guanyl-nucleotide exchange factor activity; neurotrophin TRK receptor signaling pathway; regulation of small GTPase mediated signal transduction; small GTPase regulator activity,PF00788;PF00617;PF00618;,,,,,,,,,GNDS_HUMAN,Homo sapiens (Human),Ras protein signal transduction [GO:0007265] comp132978_c1_seq1,1509,44.9304,0.50015276,99,53,,1.00E-152,Q8CD54,Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B),Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B),GO:0005261; GO:0016021; GO:0008381; GO:0005886; GO:0042391,cation channel activity; integral to membrane; mechanically-gated ion channel activity; plasma membrane; regulation of membrane potential,PF15917;PF12166;,3.00E-127,CHOYP_LOC100372622.1.2,,,,,,,PIEZ2_MOUSE,Mus musculus (Mouse),cation transport [GO:0006812]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; regulation of membrane potential [GO:0042391]; response to mechanical stimulus [GO:0009612] comp132978_c2_seq1,719,37.9694,0.7751953,16,20,,,,,,,,,2.00E-17,CHOYP_LOC655842.1.1,,,,,,,,, comp132978_c5_seq3,223,52.4664,0.46584419,0,0,,,,,,,,,1.00E-25,CHOYP_LOC100747115.1.1,,,,,,,,, comp132984_c3_seq1,1429,42.0574,0.49098465,54,321,,2.00E-172,Q9D0A0,DET1 homolog (De-etiolated-1 homolog),DET1 homolog (De-etiolated-1 homolog),GO:0005634,nucleus,PF09737;,2.00E-166,CHOYP_DET1.1.2,,,,,,,DET1_MOUSE,Mus musculus (Mouse), comp132994_c0_seq1,1451,40.6616,0.93677464,225,3913,,4.00E-95,Q6NV34,"Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34) (2,4-dienoyl-CoA reductase 2)","Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34) (2,4-dienoyl-CoA reductase 2)",GO:0008670; GO:0006631; GO:0005777,"2,4-dienoyl-CoA reductase (NADPH) activity; fatty acid metabolic process; peroxisome",,4.00E-80,CHOYP_DECR2.1.2,,,,,,,DECR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid metabolic process [GO:0006631] comp132995_c0_seq1,912,44.8465,0.44467227,27,86,,,,,,,,,4.00E-53,CHOYP_ACA1_243440.1.1,,,,,,,,, comp132997_c0_seq1,1196,38.4615,0.82803046,3,69,,2.00E-74,Q8BHH2,Ras-related protein Rab-9B,Ras-related protein Rab-9B,GO:0019003; GO:0005525; GO:0045335; GO:0030670; GO:0005886; GO:0015031; GO:0007264,GDP binding; GTP binding; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAB9B_MOUSE,Mus musculus (Mouse),"protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; small GTPase mediated signal transduction [GO:0007264]" comp132997_c0_seq2,1218,37.2742,0.77396878,15,83,,1.00E-44,Q40787,Ras-related protein Rab7,Ras-related protein Rab7,GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,2.00E-95,CHOYP_RAB9A.1.1,2.00E-81,ruditapes_c26657,,,,,RAB7_CENCI,Cenchrus ciliaris (Buffelgrass) (Pennisetum ciliare),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp133001_c0_seq1,2264,52.6502,0.36743117,73,255,,1.00E-42,Q8SX83,Protein split ends,Protein split ends,GO:0003723; GO:0016055; GO:0007411; GO:0048749; GO:0050832; GO:0007173; GO:0048106; GO:0007403; GO:0008586; GO:0035321; GO:0007400; GO:0000166; GO:0005634; GO:0007422; GO:0030177; GO:0006355; GO:0007379; GO:0006351; GO:0035222,"RNA binding; Wnt receptor signaling pathway; axon guidance; compound eye development; defense response to fungus; epidermal growth factor receptor signaling pathway; establishment of thoracic bristle planar orientation; glial cell fate determination; imaginal disc-derived wing vein morphogenesis; maintenance of imaginal disc-derived wing hair orientation; neuroblast fate determination; nucleotide binding; nucleus; peripheral nervous system development; positive regulation of Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; segment specification; transcription, DNA-dependent; wing disc pattern formation",PF00076;PF07744;,4.00E-57,CHOYP_MINT.1.1,,,,,,,SPEN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; compound eye development [GO:0048749]; defense response to fungus [GO:0050832]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of thoracic bristle planar orientation [GO:0048106]; glial cell fate determination [GO:0007403]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maintenance of imaginal disc-derived wing hair orientation [GO:0035321]; mRNA splicing, via spliceosome [GO:0000398]; neuroblast fate determination [GO:0007400]; peripheral nervous system development [GO:0007422]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sleep [GO:0030431]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]; Wnt signaling pathway [GO:0016055]" comp133001_c1_seq1,255,48.6275,0.33307824,5,18,,3.00E-12,Q96T58,Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog),Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog),GO:0007219; GO:0003723; GO:0001191; GO:0019048; GO:0000166; GO:0050769; GO:0045893; GO:0003700; GO:0003697; GO:0003714; GO:0017053,"Notch signaling pathway; RNA binding; RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; modulation by virus of host morphology or physiology; nucleotide binding; positive regulation of neurogenesis; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription corepressor activity; transcriptional repressor complex",PF00076;PF07744;,,,,,,,,,MINT_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp133002_c3_seq1,1076,45.1673,0.40627607,1,0,,1.00E-22,P51826,AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4),AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4),GO:0003690; GO:0035116; GO:0005730; GO:0006355; GO:0034612; GO:0006351,"double-stranded DNA binding; embryonic hindlimb morphogenesis; nucleolus; regulation of transcription, DNA-dependent; response to tumor necrosis factor; transcription, DNA-dependent",PF05110;,,,,,,,,,AFF3_HUMAN,Homo sapiens (Human),"embryonic hindlimb morphogenesis [GO:0035116]; regulation of transcription, DNA-templated [GO:0006355]; response to tumor necrosis factor [GO:0034612]; transcription, DNA-templated [GO:0006351]" comp133010_c0_seq1,730,42.6027,0.49931788,13,69,,1.00E-53,B1AS42,NADH-cytochrome b5 reductase-like (EC 1.6.2.2),NADH-cytochrome b5 reductase-like (EC 1.6.2.2),GO:0004128,"cytochrome-b5 reductase activity, acting on NAD(P)H",PF00970;PF00175;PF09791;,,,,,,,,,NB5R5_MOUSE,Mus musculus (Mouse), comp133010_c0_seq3,710,42.8169,0.50967843,0,5,,8.00E-32,Q6BUX2,NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase),NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase),GO:0004128; GO:0005789; GO:0016021; GO:0005741,"cytochrome-b5 reductase activity, acting on NAD(P)H; endoplasmic reticulum membrane; integral to membrane; mitochondrial outer membrane",PF00970;PF00175;,,,,,,,,,NCB5R_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii), comp133012_c0_seq2,2131,41.3421,0.44466701,134,66,,2.00E-84,Q69ZZ6,Transmembrane and coiled-coil domains protein 1,Transmembrane and coiled-coil domains protein 1,GO:0016021,integral to membrane,PF10267;,5.00E-56,CHOYP_TMCC1.1.1,,,,,,,TMCC1_MOUSE,Mus musculus (Mouse), comp133013_c2_seq1,1181,41.4056,0.43870869,0,0,,3.00E-22,P61593,Microcephalin,Microcephalin,GO:0005737; GO:0005815,cytoplasm; microtubule organizing center,PF16589;PF12258;PF12738;,,,,,,,,,MCPH1_PANTR,Pan troglodytes (Chimpanzee),cerebral cortex development [GO:0021987] comp133013_c2_seq2,1437,41.9624,0.44638603,18,1,,,,,,,,,1.00E-48,CHOYP_BRAFLDRAFT_123580.1.1,,,,,,,,, comp133018_c0_seq2,2433,41.3892,0.61696625,16,4,,2.00E-52,Q9VYY9,Ecotropic viral integration site 5 ortholog,Ecotropic viral integration site 5 ortholog,GO:0005097; GO:0007298; GO:0005737; GO:0005768; GO:0030334; GO:0032880; GO:0031982,Rab GTPase activator activity; border follicle cell migration; cytoplasm; endosome; regulation of cell migration; regulation of protein localization; vesicle,PF00566;,1.00E-83,CHOYP_LOC100378224.1.1,,,,,,,Y1727_DROME,Drosophila melanogaster (Fruit fly),activation of GTPase activity [GO:0090630]; border follicle cell migration [GO:0007298]; intracellular protein transport [GO:0006886]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338] comp133018_c0_seq3,2207,41.459,0.59018509,0,0,,4.00E-30,O60447,Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein),Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein),GO:0005097; GO:0007049; GO:0051301; GO:0008283; GO:0005737; GO:0005815; GO:0007275; GO:0005634; GO:0032851; GO:0005819,Rab GTPase activator activity; cell cycle; cell division; cell proliferation; cytoplasm; microtubule organizing center; multicellular organismal development; nucleus; positive regulation of Rab GTPase activity; spindle,PF00566;,2.00E-47,CHOYP_LOC100378224.1.1,,,,,,,EVI5_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; intracellular protein transport [GO:0006886]; multicellular organism development [GO:0007275]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]" comp133019_c1_seq1,652,32.6687,0.69641117,27,60,,7.00E-18,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,3.00E-20,CHOYP_LOC100892567.5.8,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp133019_c1_seq3,351,33.6182,0.81106649,31,43,,,,,,,,,,,2.00E-12,ruditapes_c16815,,,,,,, comp133021_c0_seq3,1816,42.1806,0.526885,1473,738,,2.00E-69,A9UMP7,Enolase-like protein ENO4,Enolase 4 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase),GO:0006096; GO:0000287; GO:0004634; GO:0000015,glycolysis; magnesium ion binding; phosphopyruvate hydratase activity; phosphopyruvate hydratase complex,PF00113;PF03952;,7.00E-104,CHOYP_LOC583138.1.1,1.00E-42,ruditapes_c15181,,,,,ENO4_XENLA,Xenopus laevis (African clawed frog),glycolytic process [GO:0006096] comp133024_c0_seq4,3623,45.8184,0.50397882,208,124,,1.00E-07,Q8CE72,Uncharacterized protein C5orf42 homolog,Uncharacterized protein C5orf42 homolog,GO:0016021,integral to membrane,PF15392;,3.00E-11,CHOYP_BRAFLDRAFT_117629.1.2,,,,,,,CE042_MOUSE,Mus musculus (Mouse),cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; palate development [GO:0060021]; protein localization to ciliary transition zone [GO:1904491]; ventricular septum development [GO:0003281] comp133026_c0_seq1,1380,39.7826,0.81139878,114,59,,2.00E-26,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133027_c0_seq2,2906,40.6745,0.46712603,0,0,,2.00E-75,Q5ZMJ7,Protein CIP2A homolog,Protein CIP2A homolog,GO:0005737; GO:0016021,cytoplasm; integral to membrane,,,,,,,,,,CIP2A_CHICK,Gallus gallus (Chicken), comp133028_c0_seq1,1091,30.9808,0.40750865,170,1020,,4.00E-30,Q9W2D6,Mitochondrial import inner membrane translocase subunit Tim10,Mitochondrial import inner membrane translocase subunit Tim10,GO:0050829; GO:0046872; GO:0005743; GO:0042719; GO:0045824; GO:0045039; GO:0008565,defense response to Gram-negative bacterium; metal ion binding; mitochondrial inner membrane; mitochondrial intermembrane space protein transporter complex; negative regulation of innate immune response; protein import into mitochondrial inner membrane; protein transporter activity,PF02953;,2.00E-38,CHOYP_PHUM_PHUM509280.1.1,,,,,,,TIM10_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; negative regulation of innate immune response [GO:0045824]; protein import into mitochondrial inner membrane [GO:0045039]; protein transport [GO:0015031] comp133030_c1_seq1,835,47.1856,0.54126926,33,317,,3.00E-81,Q9UH92,Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4),Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4),GO:0003677; GO:0005737; GO:0006112; GO:0045892; GO:0006913; GO:0005634; GO:0031325; GO:0003700; GO:0044281; GO:0006351,"DNA binding; cytoplasm; energy reserve metabolic process; negative regulation of transcription, DNA-dependent; nucleocytoplasmic transport; nucleus; positive regulation of cellular metabolic process; sequence-specific DNA binding transcription factor activity; small molecule metabolic process; transcription, DNA-dependent",PF00010;,1.00E-108,CHOYP_BRAFLDRAFT_84752.1.1,2.00E-98,ruditapes_c25138,,,,,MLX_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133032_c0_seq1,2146,45.6664,0.53702982,0,3,,3.00E-111,Q5T5U3,Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21),Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21),GO:0005096; GO:0005794; GO:0000139; GO:0007030; GO:0030054; GO:0030659; GO:0005856; GO:0051683; GO:0051684; GO:0072384; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; Golgi apparatus; Golgi membrane; Golgi organization; cell junction; cytoplasmic vesicle membrane; cytoskeleton; establishment of Golgi localization; maintenance of Golgi location; organelle transport along microtubule; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00595;PF00620;,4.00E-76,CHOYP_BRAFLDRAFT_125209.1.1,,,,,,,RHG21_HUMAN,Homo sapiens (Human),establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp133032_c0_seq2,488,43.2377,0.62532232,6,29,,3.00E-07,Q6P0Q8,Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1),Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0000287; GO:0015630; GO:0005886; GO:0006468; GO:0004674; GO:0045075; GO:0048515,ATP binding; cytoplasm; magnesium ion binding; microtubule cytoskeleton; plasma membrane; protein phosphorylation; protein serine/threonine kinase activity; regulation of interleukin-12 biosynthetic process; spermatid differentiation,PF08926;PF00595;PF00069;,,,2.00E-63,ruditapes_c8716,,,,,MAST2_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of interleukin-12 biosynthetic process [GO:0045075]; spermatid differentiation [GO:0048515] comp133032_c0_seq3,4078,45.3409,0.63956017,38,72,,,,,,,,,3.00E-80,CHOYP_ARHGAP21.1.1,,,,,,,,, comp133032_c0_seq4,3068,46.1864,0.5565101,0,0,,3.00E-108,Q5T5U3,Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21),Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21),GO:0005096; GO:0005794; GO:0000139; GO:0007030; GO:0030054; GO:0030659; GO:0005856; GO:0051683; GO:0051684; GO:0072384; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; Golgi apparatus; Golgi membrane; Golgi organization; cell junction; cytoplasmic vesicle membrane; cytoskeleton; establishment of Golgi localization; maintenance of Golgi location; organelle transport along microtubule; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00595;PF00620;,3.00E-80,CHOYP_ARHGAP21.1.1,,,,,,,RHG21_HUMAN,Homo sapiens (Human),establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp133033_c0_seq1,1339,37.416,0.3668279,4472,844,,3.00E-90,Q2KIU7,Radial spoke head protein 9 homolog,Radial spoke head protein 9 homolog,GO:0035085; GO:0035083; GO:0003341; GO:0005856,cilium axoneme; cilium axoneme assembly; cilium movement; cytoskeleton,PF04712;,4.00E-149,CHOYP_BRAFLDRAFT_121507.1.2,2.00E-170,ruditapes_c8101,,,,,RSPH9_BOVIN,Bos taurus (Bovine),axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294]; motile cilium assembly [GO:0044458] comp133035_c0_seq2,1414,45.686,0.76569302,72,45,,3.00E-153,P42337,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)",GO:0016303; GO:0035005; GO:0005943; GO:0005524; GO:0001525; GO:0006006; GO:0044029; GO:0030027; GO:2000811; GO:2000270; GO:0043524; GO:0005942; GO:0046934; GO:0048015; GO:0005886; GO:0033138; GO:0043491; GO:0030295; GO:0006468; GO:0004674; GO:2000653; GO:0040014,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ATP binding; angiogenesis; glucose metabolic process; hypomethylation of CpG island; lamellipodium; negative regulation of anoikis; negative regulation of fibroblast apoptotic process; negative regulation of neuron apoptotic process; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein kinase B signaling cascade; protein kinase activator activity; protein phosphorylation; protein serine/threonine kinase activity; regulation of genetic imprinting; regulation of multicellular organism growth",PF00454;PF00792;PF02192;PF00794;PF00613;,6.00E-78,CHOYP_PK3CA.1.1,,,,,,,PK3CA_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014] comp133036_c0_seq1,1638,43.7729,0.46503067,0,0,,4.00E-137,P48760,"Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)","Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)",GO:0005524; GO:0005743; GO:0005759; GO:0005739; GO:0006730; GO:0004326,ATP binding; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; one-carbon metabolic process; tetrahydrofolylpolyglutamate synthase activity,,,,,,,,,,FOLC_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cell proliferation [GO:0008283]; folic acid-containing compound metabolic process [GO:0006760]; glutamate metabolic process [GO:0006536]; liver development [GO:0001889]; one-carbon metabolic process [GO:0006730]; organ regeneration [GO:0031100]; tetrahydrofolylpolyglutamate biosynthetic process [GO:0046901] comp133036_c0_seq4,1571,43.3482,0.42605368,0,0,,1.00E-88,B5VSC3,Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase),Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase),GO:0005524; GO:0005743; GO:0005759; GO:0006730; GO:0004326,ATP binding; mitochondrial inner membrane; mitochondrial matrix; one-carbon metabolic process; tetrahydrofolylpolyglutamate synthase activity,,5.00E-67,CHOYP_BRAFLDRAFT_284412.1.1,,,,,,,FOLE_YEAS6,Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast),one-carbon metabolic process [GO:0006730] comp133037_c0_seq2,1827,44.2255,0.52694024,69,53,,7.00E-14,Q12830,Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),GO:0016589; GO:0009952; GO:0007420; GO:0006338; GO:0005737; GO:0001892; GO:0007492; GO:0000122; GO:0045893; GO:0043565; GO:0008134; GO:0006351; GO:0008270,"NURF complex; anterior/posterior pattern specification; brain development; chromatin remodeling; cytoplasm; embryonic placenta development; endoderm development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF00628;PF15612;PF15613;,1.00E-43,CHOYP_RGD1310712.1.1,,,,,,,BPTF_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]" comp133038_c0_seq1,2473,42.0946,0.38844409,148,213,,0,Q4V7C6,GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase),GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase),GO:0005524; GO:0003922; GO:0003921; GO:0005829; GO:0019899; GO:0006541; GO:0016462; GO:0042493,ATP binding; GMP synthase (glutamine-hydrolyzing) activity; GMP synthase activity; cytosol; enzyme binding; glutamine metabolic process; pyrophosphatase activity; response to drug,PF00117;PF00958;PF02540;,0,CHOYP_GUAA.1.1,,,,,,,GUAA_RAT,Rattus norvegicus (Rat),glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to drug [GO:0042493]; response to L-cysteine [GO:1901367] comp133038_c0_seq2,590,43.0508,0.35688508,0,0,,2.00E-63,Q5RA96,GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase),GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase),GO:0005524; GO:0006177; GO:0003922; GO:0005737; GO:0006541; GO:0016462,ATP binding; GMP biosynthetic process; GMP synthase (glutamine-hydrolyzing) activity; cytoplasm; glutamine metabolic process; pyrophosphatase activity,PF00117;PF00958;PF02540;,,,,,,,,,GUAA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177] comp133041_c1_seq3,928,39.8707,0.43584381,4,37,,7.00E-116,Q09332,UDP-glucose:glycoprotein glucosyltransferase (UGT) (dUGT) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase),UDP-glucose:glycoprotein glucosyltransferase (UGT) (dUGT) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase),GO:0003980; GO:0005788; GO:0005635; GO:0006486; GO:0005791,UDP-glucose:glycoprotein glucosyltransferase activity; endoplasmic reticulum lumen; nuclear envelope; protein glycosylation; rough endoplasmic reticulum,PF01501;PF06427;,6.00E-82,CHOYP_UGGG1.1.1,,,,,,,UGGG_DROME,Drosophila melanogaster (Fruit fly),protein glycosylation [GO:0006486] comp133042_c2_seq2,1102,42.0145,0.56307477,0,18,,4.00E-90,Q8TEL6,Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS),Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS),GO:0031464; GO:0019902; GO:0016567; GO:0006511,Cul4A-RING ubiquitin ligase complex; phosphatase binding; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF12463;,4.00E-142,CHOYP_LOC101163318.1.1,,,,,,,TP4AP_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp133042_c2_seq3,1114,42.1005,0.57508151,14,0,,8.00E-88,Q8TEL6,Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS),Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS),GO:0031464; GO:0019902; GO:0016567; GO:0006511,Cul4A-RING ubiquitin ligase complex; phosphatase binding; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF12463;,,,,,,,,,TP4AP_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp133048_c0_seq1,1532,33.1593,0.49207975,422,945,,6.00E-62,Q9VAI1,"Probable complex I intermediate-associated protein 30, mitochondrial","Complex I intermediate-associated protein 30, mitochondrial",GO:0006120; GO:0005747; GO:0051082,"mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I; unfolded protein binding",PF08547;,,,1.00E-27,ruditapes2_c1877,,,,,CIA30_DROME,Drosophila melanogaster (Fruit fly),"mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion organization [GO:0007005]; oxidative phosphorylation [GO:0006119]; response to heat [GO:0009408]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to starvation [GO:0042594]" comp133049_c0_seq2,1813,40.6509,0.16095835,0,0,,9.00E-74,F1MJR8,Inactive serine/threonine-protein kinase TEX14 (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein),Inactive serine/threonine-protein kinase TEX14 (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein),GO:0005524; GO:0008608; GO:0051301; GO:0000777; GO:0005737; GO:0045171; GO:0043063; GO:0000776; GO:0007140; GO:0030496; GO:0051306; GO:0007094; GO:0032466; GO:0032091; GO:0004672,ATP binding; attachment of spindle microtubules to kinetochore; cell division; condensed chromosome kinetochore; cytoplasm; intercellular bridge; intercellular bridge organization; kinetochore; male meiosis; midbody; mitotic sister chromatid separation; mitotic spindle assembly checkpoint; negative regulation of cytokinesis; negative regulation of protein binding; protein kinase activity,PF12796;PF07714;,,,,,,,,,TEX14_BOVIN,Bos taurus (Bovine),attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; intercellular bridge organization [GO:0043063]; male meiosis [GO:0007140]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of cytokinesis [GO:0032466]; negative regulation of protein binding [GO:0032091] comp133049_c0_seq4,799,37.1715,0.25751903,0,0,,2.00E-14,Q5F478,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44),,,PF00023;PF12796;,,,,,,,,,ANR44_CHICK,Gallus gallus (Chicken), comp133049_c0_seq5,1572,39.6947,0.16179306,0,0,,3.00E-55,Q7M6U3,Inactive serine/threonine-protein kinase TEX14 (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein),Inactive serine/threonine-protein kinase TEX14 (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein),GO:0005524; GO:0008608; GO:0051301; GO:0000777; GO:0005737; GO:0045171; GO:0043063; GO:0000776; GO:0007140; GO:0030496; GO:0051306; GO:0007094; GO:0032466; GO:0032091; GO:0004672,ATP binding; attachment of spindle microtubules to kinetochore; cell division; condensed chromosome kinetochore; cytoplasm; intercellular bridge; intercellular bridge organization; kinetochore; male meiosis; midbody; mitotic sister chromatid separation; mitotic spindle assembly checkpoint; negative regulation of cytokinesis; negative regulation of protein binding; protein kinase activity,PF12796;PF07714;,2.00E-21,CHOYP_TEX14.1.1,,,,,,,TEX14_MOUSE,Mus musculus (Mouse),attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; intercellular bridge organization [GO:0043063]; male meiosis [GO:0007140]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of cytokinesis [GO:0032466]; negative regulation of protein binding [GO:0032091] comp133050_c0_seq2,1101,39.9637,0.60735609,97,1452,,9.00E-83,Q5M9G0,Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase),Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase),GO:0004132; GO:0009165; GO:0008270,dCMP deaminase activity; nucleotide biosynthetic process; zinc ion binding,PF00383;,5.00E-103,CHOYP_NEMVEDRAFT_V1G233184.1.1,,,,,,,DCTD_RAT,Rattus norvegicus (Rat),nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220] comp133059_c1_seq1,1201,46.2115,0.7197235,84,71,,3.00E-38,Q8N328,PiggyBac transposable element-derived protein 3,PiggyBac transposable element-derived protein 3,,,PF13843;,,,2.00E-11,ruditapes_c8206,,,,,PGBD3_HUMAN,Homo sapiens (Human), comp133063_c0_seq1,2383,41.5023,0.41701242,153,196,,2.00E-43,Q5PQQ9,Centrosomal protein of 70 kDa (Cep70),Centrosomal protein of 70 kDa (Cep70),GO:0005813; GO:0005737; GO:0031965,centrosome; cytoplasm; nuclear membrane,,6.00E-55,CHOYP_LOC100370976.2.2,,,,,,,CEP70_RAT,Rattus norvegicus (Rat), comp133067_c0_seq1,1543,47.4401,0.76918982,95,90,,0,Q6DFF6,Kelch-like protein 20,Kelch-like protein 20,GO:0031463; GO:0016605; GO:0005737; GO:0019964; GO:0043066; GO:0048471; GO:0043161; GO:0004842,Cul3-RING ubiquitin ligase complex; PML body; cytoplasm; interferon-gamma binding; negative regulation of apoptotic process; perinuclear region of cytoplasm; proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF07707;PF00651;PF01344;,0,CHOYP_KLH20.2.2,,,,,,,KLH20_XENLA,Xenopus laevis (African clawed frog),Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] comp133067_c0_seq2,481,41.7879,0.64465299,0,0,,4.00E-19,O93567,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),GO:0003677; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_CHICK,Gallus gallus (Chicken),"transcription, DNA-templated [GO:0006351]" comp133072_c0_seq3,946,38.1607,0.86150419,0,0,,1.00E-53,O43402,ER membrane protein complex subunit 8 (Neighbor of COX4) (Protein FAM158B),ER membrane protein complex subunit 8 (Neighbor of COX4) (Protein FAM158B),GO:0072546; GO:0005739; GO:0005634,ER membrane protein complex; mitochondrion; nucleus,PF03665;,,,,,,,,,EMC8_HUMAN,Homo sapiens (Human), comp133072_c0_seq4,990,36.8687,0.76669633,9,22,,,,,,,,,3.00E-48,CHOYP_BRAFLDRAFT_260197.1.1,,,,,,,,, comp133075_c0_seq1,1639,41.2447,0.4780076,271,20,,3.00E-177,Q8BI55,Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1),Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1),GO:0005524; GO:0005794; GO:0046872; GO:0004674; GO:0004712,ATP binding; Golgi apparatus; metal ion binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity,PF00069;,0,CHOYP_LOC100370831.1.1,,,,,,,DYRK4_MOUSE,Mus musculus (Mouse), comp133075_c1_seq1,854,46.7213,0.53781777,2,0,,2.00E-11,Q92630,Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0042771; GO:0000287; GO:0030145; GO:0051534; GO:0005634; GO:0045725; GO:0004674; GO:0004712; GO:0004713; GO:0030529; GO:0007224; GO:0043130; GO:0000151,ATP binding; cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; magnesium ion binding; manganese ion binding; negative regulation of NFAT protein import into nucleus; nucleus; positive regulation of glycogen biosynthetic process; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; ribonucleoprotein complex; smoothened signaling pathway; ubiquitin binding; ubiquitin ligase complex,PF00069;,,,,,,,,,DYRK2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224] comp133075_c1_seq2,1087,45.5382,0.55179682,26,0,,,,,,,,,2.00E-25,CHOYP_LOC100370831.1.1,,,,,,,,, comp133076_c0_seq2,1102,35.9347,0.50642833,2,1,,4.00E-54,Q9NZS9,Bifunctional apoptosis regulator (RING finger protein 47),Bifunctional apoptosis regulator (RING finger protein 47),GO:0006915; GO:0005789; GO:0005887; GO:0043066; GO:0005198; GO:0008270,apoptotic process; endoplasmic reticulum membrane; integral to plasma membrane; negative regulation of apoptotic process; structural molecule activity; zinc ion binding,PF00536;,,,,,,,,,BFAR_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp133080_c0_seq1,1080,42.7778,0.2540692,135,1,,,,,,,,,6.00E-32,CHOYP_LOC100369350.5.6,,,,,,,,, comp133082_c0_seq1,2511,34.2095,0.65739812,19,36,,8.00E-32,Q9SN43,CBL-interacting serine/threonine-protein kinase 12 (EC 2.7.11.1) (SNF1-related kinase 3.9) (SOS2-like protein kinase PKS8),CBL-interacting serine/threonine-protein kinase 12 (EC 2.7.11.1) (SNF1-related kinase 3.9) (SOS2-like protein kinase PKS8),GO:0005524; GO:0004674; GO:0007165,ATP binding; protein serine/threonine kinase activity; signal transduction,PF03822;PF00069;,,,3.00E-70,ruditapes_c11052,,,,,CIPKC_ARATH,Arabidopsis thaliana (Mouse-ear cress),signal transduction [GO:0007165] comp133082_c0_seq2,2412,34.0796,0.64625861,0,52,,5.00E-123,Q9PU85,Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) (qpim),Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) (qpim),GO:0005524; GO:0005737; GO:0004674,ATP binding; cytoplasm; protein serine/threonine kinase activity,PF00069;,2.00E-117,CHOYP_MDHC.1.1,,,2.00E-117,DV736298.p.cg.6,2,,PIM3_COTJA,Coturnix coturnix japonica (Japanese quail) (Coturnix japonica),negative regulation of apoptotic process [GO:0043066] comp133085_c0_seq1,1096,36.7701,0.7040389,19,118,,4.00E-22,P49582,Neuronal acetylcholine receptor subunit alpha-7,Neuronal acetylcholine receptor subunit alpha-7,GO:0042113; GO:0042110; GO:0004889; GO:0016324; GO:0008306; GO:0048149; GO:0035095; GO:0030054; GO:0006897; GO:0009897; GO:0060112; GO:0016021; GO:0007613; GO:0050728; GO:0032691; GO:0032715; GO:0032720; GO:0001988; GO:0045211; GO:0042391; GO:0014061; GO:0032225; GO:0032094; GO:0030317; GO:0007271,"B cell activation; T cell activation; acetylcholine-activated cation-selective channel activity; apical plasma membrane; associative learning; behavioral response to ethanol; behavioral response to nicotine; cell junction; endocytosis; external side of plasma membrane; generation of ovulation cycle rhythm; integral to membrane; memory; negative regulation of inflammatory response; negative regulation of interleukin-1 beta production; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure; postsynaptic membrane; regulation of membrane potential; regulation of norepinephrine secretion; regulation of synaptic transmission, dopaminergic; response to food; sperm motility; synaptic transmission, cholinergic",PF02931;PF02932;,,,,,,,,,ACHA7_MOUSE,Mus musculus (Mouse),"activation of MAPK activity [GO:0000187]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; endocytosis [GO:0006897]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; memory [GO:0007613]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; ovulation cycle [GO:0042698]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; sperm motility [GO:0030317]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110]" comp133088_c0_seq2,1272,40.8019,0.85150554,104,274,,3.00E-06,O75382,Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),GO:0005737; GO:0005769; GO:0007399; GO:0008022; GO:0015031; GO:0008270,cytoplasm; early endosome; nervous system development; protein C-terminus binding; protein transport; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,4.00E-46,ruditapes_c7738,,,,,TRIM3_HUMAN,Homo sapiens (Human),nervous system development [GO:0007399]; protein transport [GO:0015031] comp133090_c0_seq1,1306,42.6493,0.93137055,0,17,,4.00E-36,P50941,3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),GO:0004316; GO:0051287; GO:0050661; GO:0030497,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NAD binding; NADP binding; fatty acid elongation,,,,,,,,,,FABG_RICPR,Rickettsia prowazekii (strain Madrid E),fatty acid elongation [GO:0030497] comp133090_c0_seq2,1294,42.5811,0.92551473,36,323,,2.00E-39,Q9WYG0,Uncharacterized oxidoreductase TM_0325 (EC 1.-.-.-),Uncharacterized oxidoreductase TM_0325 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,,1.00E-41,CHOYP_PHUM_PHUM411900.1.1,1.00E-64,ruditapes_c8217,,,,,Y325_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099), comp133091_c1_seq1,2107,42.4775,0.7167775,0,10,,5.00E-29,Q90330,Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase),Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase),GO:0005524; GO:0005783; GO:0005768; GO:0005007; GO:0016021; GO:0018108; GO:0005886; GO:0008284,ATP binding; endoplasmic reticulum; endosome; fibroblast growth factor-activated receptor activity; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of cell proliferation,PF07679;PF07714;,,,,,,,,,FGFR4_COTCO,Coturnix coturnix (Common quail) (Tetrao coturnix),positive regulation of cell proliferation [GO:0008284] comp133091_c1_seq2,2082,42.7474,0.71589455,2,3,,5.00E-29,Q90330,Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase),Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase),GO:0005524; GO:0005783; GO:0005768; GO:0005007; GO:0016021; GO:0018108; GO:0005886; GO:0008284,ATP binding; endoplasmic reticulum; endosome; fibroblast growth factor-activated receptor activity; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of cell proliferation,PF07679;PF07714;,,,,,,,,,FGFR4_COTCO,Coturnix coturnix (Common quail) (Tetrao coturnix),positive regulation of cell proliferation [GO:0008284] comp133092_c0_seq1,561,33.5116,0.19081093,14,18,,2.00E-06,Q17850,Serine/threonine-protein kinase pak-1 (EC 2.7.11.1) (CePAK) (p21-activated kinase 1) (PAK1),Serine/threonine-protein kinase pak-1 (EC 2.7.11.1) (CePAK) (p21-activated kinase 1) (PAK1),GO:0005524; GO:0005525; GO:0030424; GO:0009986; GO:0005829; GO:0010172; GO:0035262; GO:0030056; GO:0031581; GO:0040039; GO:0016021; GO:0002119; GO:0043025; GO:0005886; GO:0004672; GO:0004674,ATP binding; GTP binding; axon; cell surface; cytosol; embryonic body morphogenesis; gonad morphogenesis; hemidesmosome; hemidesmosome assembly; inductive cell migration; integral to membrane; nematode larval development; neuronal cell body; plasma membrane; protein kinase activity; protein serine/threonine kinase activity,PF00786;PF00069;,,,,,,,,,PAK1_CAEEL,Caenorhabditis elegans,actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; embryonic body morphogenesis [GO:0010172]; embryonic morphogenesis [GO:0048598]; gonad morphogenesis [GO:0035262]; hemidesmosome assembly [GO:0031581]; inductive cell migration [GO:0040039]; nematode larval development [GO:0002119] comp133094_c0_seq1,435,33.3333,0.58133641,20,56,,,,,,,,,,,8.00E-24,ruditapes_c29520,,,,,,, comp1330_c0_seq1,238,43.6975,0.53210587,3,0,,3.00E-11,A8E627,Poly(U)-specific endoribonuclease-D (EC 3.1.-.-) (Protein endoU-D) (Uridylate-specific endoribonuclease-D) (XendoU-D),Poly(U)-specific endoribonuclease-D (EC 3.1.-.-) (Protein endoU-D) (Uridylate-specific endoribonuclease-D) (XendoU-D),GO:0003723; GO:0004521; GO:0005576; GO:0046872,RNA binding; endoribonuclease activity; extracellular region; metal ion binding,PF09412;,,,,,,,,,ENDUD_XENLA,Xenopus laevis (African clawed frog), comp133100_c1_seq1,957,42.0063,0.527428,0,0,,4.00E-64,B1H2T2,Deleted in autism protein 1 homolog,Deleted in autism protein 1 homolog,GO:0060038; GO:0005615; GO:0014066,cardiac muscle cell proliferation; extracellular space; regulation of phosphatidylinositol 3-kinase cascade,PF12260;,,,,,,,,,DIA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp133100_c1_seq2,1565,40.1278,0.53192957,24,64,,4.00E-91,B1H2T2,Deleted in autism protein 1 homolog,Deleted in autism protein 1 homolog,GO:0060038; GO:0005615; GO:0014066,cardiac muscle cell proliferation; extracellular space; regulation of phosphatidylinositol 3-kinase cascade,PF12260;,,,,,,,,,DIA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp133102_c0_seq1,1365,43.0769,0.68989936,79,2,,3.00E-122,Q9NGQ2,Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3),GO:0005524; GO:0030659; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005543; GO:0006810,ATP binding; cytoplasmic vesicle membrane; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; phospholipid binding; transport,PF00225;PF16183;PF00169;,0,CHOYP_NEMVEDRAFT_V1G100691.1.2,,,,,,,KIF1_DICDI,Dictyostelium discoideum (Slime mold),plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496] comp133102_c0_seq2,652,46.319,0.45895122,12,1,,2.00E-32,Q6S003,Kinesin-related protein 8 (Kinesin family member 8) (Kinesin-4),Kinesin-related protein 8 (Kinesin family member 8) (Kinesin-4),GO:0005524; GO:0051301; GO:0005737; GO:0031122; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007067; GO:0006810,ATP binding; cell division; cytoplasm; cytoplasmic microtubule organization; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; mitosis; transport,PF00225;PF00400;,7.00E-54,CHOYP_LOC590618.1.1,,,,,,,KIF8_DICDI,Dictyostelium discoideum (Slime mold),cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; transport [GO:0006810] comp133102_c0_seq3,304,44.4079,0.33516846,4,0,,,,,,,,,1.00E-33,CHOYP_LOC100366906.1.1,,,,,,,,, comp133111_c0_seq1,1426,33.8008,0.39929367,1905,91,,6.00E-33,O35817,A-kinase anchor protein 14 (AKAP-14) (TAKAP-1.2) (Testis-specific A-kinase-anchoring protein TAKAP-80),A-kinase anchor protein 14 (AKAP-14) (TAKAP-1.2) (Testis-specific A-kinase-anchoring protein TAKAP-80),GO:0005737; GO:0007283,cytoplasm; spermatogenesis,PF14469;,3.00E-38,CHOYP_LOC100374430.1.1,7.00E-107,ruditapes2_c379,,,,,AKA14_RAT,Rattus norvegicus (Rat),spermatogenesis [GO:0007283] comp133115_c1_seq3,1230,46.4228,0.63682632,59,123,,2.00E-62,Q7ZVQ8,Influenza virus NS1A-binding protein homolog B (NS1-BP homolog B) (NS1-binding protein homolog B),Influenza virus NS1A-binding protein homolog B (NS1-BP homolog B) (NS1-binding protein homolog B),GO:0005737; GO:0005856; GO:0005634,cytoplasm; cytoskeleton; nucleus,PF07707;PF00651;PF01344;,,,,,,,,,NS1BB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp133126_c0_seq1,2828,40.488,0.31121165,156,78,,,,,,,,,2.00E-11,CHOYP_LOC100373865.1.2,,,,,,,,, comp133126_c1_seq1,1493,40.2545,0.44725599,17,5,,2.00E-24,Q7TSH4,Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (Cep110) (Cp110),Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (Cep110) (Cp110),GO:0030030; GO:0005814; GO:0007099; GO:0051298; GO:0032465,cell projection organization; centriole; centriole replication; centrosome duplication; regulation of cytokinesis,,,,,,,,,,CP110_MOUSE,Mus musculus (Mouse),centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; ciliary basal body organization [GO:0032053]; negative regulation of cilium assembly [GO:1902018]; positive regulation of cilium assembly [GO:0045724]; regulation of cytokinesis [GO:0032465] comp133126_c1_seq2,1532,40.4047,0.46445829,10,0,,,,,,,,,2.00E-26,CHOYP_LOC100373865.1.2,,,,,,,,, comp133127_c0_seq1,1185,36.7932,0.33157013,52,117,,1.00E-53,Q8BZG5,Protein RRNAD1,Protein RRNAD1,GO:0016021,integral to membrane,PF13679;,,,,,,,,,RRNAD_MOUSE,Mus musculus (Mouse), comp133129_c0_seq1,1736,36.6359,0.42269644,20,159,,7.00E-09,Q9SE51,Surfeit locus protein 1 (Surfeit 1) (Cytochrome c oxidase assembly protein SURF1) (Protein EMBRYO DEFECTIVE 3121) (Surfeit locus 1 cytochrome c oxidase biogenesis protein),Surfeit locus protein 1 (Surfeit 1) (Cytochrome c oxidase assembly protein SURF1) (Protein EMBRYO DEFECTIVE 3121) (Surfeit locus 1 cytochrome c oxidase biogenesis protein),GO:0016021; GO:0005743; GO:0005739,integral to membrane; mitochondrial inner membrane; mitochondrion,PF02104;,,,,,,,,,SURF1_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp133129_c0_seq2,1747,36.5197,0.40586746,101,294,,5.00E-47,P09925,Surfeit locus protein 1,Surfeit locus protein 1,GO:0006754; GO:0004129; GO:0016021; GO:0005743; GO:0005739; GO:0006119,ATP biosynthetic process; cytochrome-c oxidase activity; integral to membrane; mitochondrial inner membrane; mitochondrion; oxidative phosphorylation,PF02104;,,,,,,,,,SURF1_MOUSE,Mus musculus (Mouse),ATP biosynthetic process [GO:0006754]; oxidative phosphorylation [GO:0006119] comp133131_c0_seq1,1072,37.7799,0.53992902,405,1068,,,,,,,,,3.00E-17,CHOYP_LOC409131.1.2,3.00E-21,ruditapes_c4549,,,,,,, comp133131_c0_seq2,1147,37.1404,0.52270956,450,339,,3.00E-70,P83941,Transcription elongation factor B polypeptide 1 (Elongin 15 kDa subunit) (Elongin-C) (EloC) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog),Transcription elongation factor B polypeptide 1 (Elongin 15 kDa subunit) (Elongin-C) (EloC) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog),GO:0030891; GO:0005634; GO:0032968; GO:0006351; GO:0006511,"VCB complex; nucleus; positive regulation of transcription elongation from RNA polymerase II promoter; transcription, DNA-dependent; ubiquitin-dependent protein catabolic process",PF03931;,1.00E-98,CHOYP_ELOC.1.1,1.00E-13,ruditapes2_c1163,2.00E-100,BQ426921.p.cg.6,8,,ELOC_RAT,Rattus norvegicus (Rat),"positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; transcription, DNA-templated [GO:0006351]" comp133137_c0_seq2,1792,41.9643,0.45990096,47,175,,2.00E-155,Q6NUQ1,RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1),RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1),GO:0031572; GO:0005783; GO:0005789; GO:0015031; GO:0016192,G2 DNA damage checkpoint; endoplasmic reticulum; endoplasmic reticulum membrane; protein transport; vesicle-mediated transport,PF04437;,2.00E-33,CHOYP_RINT1.1.1,,,,,,,RINT1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of signal transduction involved in mitotic G2 DNA damage checkpoint [GO:1902504]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp133141_c0_seq1,1270,41.4961,0.50682353,0,9,,4.00E-142,Q66IL0,Chitinase domain-containing protein 1,Chitinase domain-containing protein 1,GO:0005975; GO:0006032; GO:0004568; GO:0005576; GO:0005764,carbohydrate metabolic process; chitin catabolic process; chitinase activity; extracellular region; lysosome,PF00704;,1.00E-55,CHOYP_LOC100544553.1.1,,,,,,,CHID1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; inflammatory response [GO:0006954] comp133141_c0_seq2,1300,41.1538,0.52043005,11,68,,,,,,,,,1.00E-55,CHOYP_LOC100544553.1.1,,,,,,,,, comp133142_c0_seq1,3397,31.9988,0.41666841,3134,5577,,1.00E-18,P01109,Myc proto-oncogene protein (c-Myc),Myc proto-oncogene protein (c-Myc),GO:0070888; GO:0000165; GO:0060070; GO:0007050; GO:0006879; GO:0034644; GO:0035690; GO:0006338; GO:0048730; GO:0051782; GO:0048147; GO:0045656; GO:0000122; GO:0005730; GO:0005654; GO:2000573; GO:0043280; GO:0050679; GO:0048146; GO:2001022; GO:0045944; GO:0043234; GO:0032204; GO:0006974; GO:0010332; GO:0003700; GO:0006351,"E-box binding; MAPK cascade; canonical Wnt receptor signaling pathway; cell cycle arrest; cellular iron ion homeostasis; cellular response to UV; cellular response to drug; chromatin remodeling; epidermis morphogenesis; negative regulation of cell division; negative regulation of fibroblast proliferation; negative regulation of monocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; positive regulation of DNA biosynthetic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of response to DNA damage stimulus; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of telomere maintenance; response to DNA damage stimulus; response to gamma radiation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00010;PF02344;PF01056;,2.00E-19,CHOYP_MYC.2.2,6.00E-42,ruditapes_c14115,,,,,MYC_CHICK,Gallus gallus (Chicken),"epidermis morphogenesis [GO:0048730]; transcription, DNA-templated [GO:0006351]" comp133145_c1_seq1,1668,40.2278,0.4260061,57,1983,,2.00E-17,Q700K0,SCO-spondin,SCO-spondin,GO:0007155; GO:0005615,cell adhesion; extracellular space,PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;,,,,,,,,,SSPO_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp133146_c0_seq1,879,38.6803,0.51879662,375,1245,,1.00E-89,Q1LZ96,ATP synthase mitochondrial F1 complex assembly factor 2,ATP synthase mitochondrial F1 complex assembly factor 2,GO:0005739; GO:0016607; GO:0043461,mitochondrion; nuclear speck; proton-transporting ATP synthase complex assembly,PF07542;,2.00E-31,CHOYP_LOC100642891.1.1,3.00E-71,ruditapes_c22183,,,,,ATPF2_BOVIN,Bos taurus (Bovine),proton-transporting ATP synthase complex assembly [GO:0043461] comp133148_c1_seq1,2968,41.8801,0.40568427,6,4,,5.00E-26,Q5R5U3,Zinc finger protein 271,Zinc finger protein 271,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN271_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133148_c1_seq3,2981,41.8987,0.40365697,6,12,,5.00E-25,Q1H9T6,Zinc finger and BTB domain-containing protein 48 (Krueppel-related zinc finger protein 3) (Protein HKR3),Zinc finger and BTB domain-containing protein 48 (Krueppel-related zinc finger protein 3) (Protein HKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT48_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133150_c0_seq1,1931,39.4096,0.83590861,42,112,,,,,,,,,,,2.00E-33,ruditapes_c23902,,,,,,, comp133150_c1_seq2,1120,38.3036,1.12520819,6,0,,9.00E-63,Q3T052,Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4),Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4),GO:0006953; GO:0005576; GO:0030212; GO:0004867,acute-phase response; extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH4_BOVIN,Bos taurus (Bovine),acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212] comp133150_c1_seq4,1025,40,1.05002956,0,0,,5.00E-68,Q5RB37,Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,5.00E-14,CHOYP_BRAFLDRAFT_215239.1.3,,,,,,,ITIH3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),hyaluronan metabolic process [GO:0030212] comp133153_c0_seq6,401,39.1521,0.6449238,21,28,,1.00E-06,Q7TSL3,F-box only protein 11,F-box only protein 11,GO:0005694; GO:0005634; GO:0004842; GO:0008270,chromosome; nucleus; ubiquitin-protein ligase activity; zinc ion binding,PF12937;PF02207;,,,,,,,,,FBX11_RAT,Rattus norvegicus (Rat),sensory perception of sound [GO:0007605] comp133154_c0_seq1,1087,34.2226,0.4564446,114,475,,5.00E-18,Q76MT4,ESF1 homolog (ABT1-associated protein),ESF1 homolog (ABT1-associated protein),GO:0005730; GO:0005654; GO:0006355; GO:0006351,"nucleolus; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08159;,,,,,,,,,ESF1_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133155_c0_seq1,579,47.8411,0.5169898,30,20,,,,,,,,,8.00E-21,CHOYP_UBP24.1.1,,,,,,,,, comp133155_c1_seq1,1571,48.9497,0.45722421,0,0,,3.00E-149,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,4.00E-100,CHOYP_UBP24.1.1,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp133157_c0_seq1,1399,32.5232,0.41708065,237,1308,,5.00E-07,Q2TBX7,Coiled-coil domain-containing protein 86,Coiled-coil domain-containing protein 86,GO:0005634,nucleus,PF03879;,1.00E-16,CHOYP_PCKG.1.2,4.00E-40,ruditapes_c7895,,,,,CCD86_BOVIN,Bos taurus (Bovine),rRNA processing [GO:0006364] comp13315_c0_seq1,216,41.2037,0.77899106,2,1,,2.00E-07,Q9ULD5,Zinc finger protein 777,Zinc finger protein 777,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12417;PF01352;PF00096;,,,,,,,,,ZN777_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133160_c0_seq1,1163,43.5942,0.48314829,117,719,,4.00E-161,A7RWD2,Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog,Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog,GO:0016226,iron-sulfur cluster assembly,PF00400;,4.00E-98,CHOYP_CIAO1.1.1,,,,,,,CIAO1_NEMVE,Nematostella vectensis (Starlet sea anemone),iron-sulfur cluster assembly [GO:0016226] comp133162_c0_seq1,1080,38.0556,0.5250891,242,2724,,5.00E-54,Q5BJJ7,Protein BCCIP homolog,Protein BCCIP homolog,GO:0006281; GO:0007049; GO:0005634,DNA repair; cell cycle; nucleus,PF13862;,8.00E-31,CHOYP_LOC100369270.1.1,,,,,,,BCCIP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle [GO:0007049]; DNA repair [GO:0006281] comp133166_c0_seq1,2073,39.508,0.44312351,294,4965,,0,P51650,"Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase)","Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase)",GO:0051287; GO:0031406; GO:0007417; GO:0009450; GO:0005739; GO:0006105; GO:0004777; GO:0009013,NAD binding; carboxylic acid binding; central nervous system development; gamma-aminobutyric acid catabolic process; mitochondrion; succinate metabolic process; succinate-semialdehyde dehydrogenase (NAD+) activity; succinate-semialdehyde dehydrogenase [NAD(P)+] activity,PF00171;,2.00E-73,CHOYP_LOC584281.1.1,,,,,,,SSDH_RAT,Rattus norvegicus (Rat),central nervous system development [GO:0007417]; gamma-aminobutyric acid catabolic process [GO:0009450]; oxidation-reduction process [GO:0055114]; succinate metabolic process [GO:0006105] comp133167_c0_seq1,983,39.9797,0.85356554,12,111,,2.00E-53,O70497,Ficolin-2 (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin-beta) (L-ficolin),Ficolin-2 (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin-beta) (L-ficolin),GO:0005581; GO:0001867,"collagen; complement activation, lectin pathway",PF01391;PF00147;,2.00E-12,CHOYP_BRAFLDRAFT_59661.1.6,,,,,,,FCN2_MOUSE,Mus musculus (Mouse),"cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]" comp133167_c0_seq2,967,39.607,0.88629565,0,0,,7.00E-49,Q9WTS8,Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin),Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin),GO:0005581; GO:0045087; GO:0046872,collagen; innate immune response; metal ion binding,PF01391;PF00147;,2.00E-12,CHOYP_BRAFLDRAFT_59661.1.6,,,,,,,FCN1_RAT,Rattus norvegicus (Rat),cell surface pattern recognition receptor signaling pathway [GO:0002752]; G-protein coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; positive regulation of interleukin-8 secretion [GO:2000484] comp133169_c0_seq1,3092,43.1436,0.33616524,0,0,,1.00E-97,Q15637,Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162),Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162),GO:0033327; GO:0003723; GO:0022402; GO:0000389; GO:0030238; GO:0050810; GO:0006355; GO:0005840; GO:0005681; GO:0003714; GO:0006351; GO:0008270,"Leydig cell differentiation; RNA binding; cell cycle process; mRNA 3'-splice site recognition; male sex determination; regulation of steroid biosynthetic process; regulation of transcription, DNA-dependent; ribosome; spliceosomal complex; transcription corepressor activity; transcription, DNA-dependent; zinc ion binding",PF00013;PF16275;PF00098;,,,,,,,,,SF01_HUMAN,Homo sapiens (Human),"Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; regulation of steroid biosynthetic process [GO:0050810]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal complex assembly [GO:0000245]; transcription, DNA-templated [GO:0006351]" comp133169_c0_seq2,3106,43.1423,0.34161937,0,0,,6.00E-22,O01367,Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F),Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F),GO:0007475; GO:0008366; GO:0007155; GO:0005737; GO:0030718; GO:0008347; GO:0003730; GO:0008078; GO:0016203; GO:0007521; GO:0005634; GO:0007438; GO:0000381; GO:0008016; GO:0045214; GO:0007525; GO:0007284,"apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon ensheathment; cell adhesion; cytoplasm; germ-line stem cell maintenance; glial cell migration; mRNA 3'-UTR binding; mesodermal cell migration; muscle attachment; muscle cell fate determination; nucleus; oenocyte development; regulation of alternative mRNA splicing, via spliceosome; regulation of heart contraction; sarcomere organization; somatic muscle development; spermatogonial cell division",PF00013;PF16544;,,,,,,,,,HOW_DROME,Drosophila melanogaster (Fruit fly),"apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]" comp133169_c0_seq3,3168,43.2765,0.34612373,0,0,,3.00E-129,Q15637,Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162),Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162),GO:0033327; GO:0003723; GO:0022402; GO:0000389; GO:0030238; GO:0050810; GO:0006355; GO:0005840; GO:0005681; GO:0003714; GO:0006351; GO:0008270,"Leydig cell differentiation; RNA binding; cell cycle process; mRNA 3'-splice site recognition; male sex determination; regulation of steroid biosynthetic process; regulation of transcription, DNA-dependent; ribosome; spliceosomal complex; transcription corepressor activity; transcription, DNA-dependent; zinc ion binding",PF00013;PF16275;PF00098;,2.00E-150,CHOYP_RPC1.1.1,,,,,,,SF01_HUMAN,Homo sapiens (Human),"Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; regulation of steroid biosynthetic process [GO:0050810]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal complex assembly [GO:0000245]; transcription, DNA-templated [GO:0006351]" comp133169_c0_seq4,3182,43.2747,0.3513678,0,0,,8.00E-73,Q4WXV6,Branchpoint-bridging protein,Branchpoint-bridging protein,GO:0003723; GO:0008380; GO:0006397; GO:0005681; GO:0008270,RNA binding; RNA splicing; mRNA processing; spliceosomal complex; zinc ion binding,PF00013;PF16275;PF00098;,2.00E-150,CHOYP_RPC1.1.1,,,,,,,BBP_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),"mRNA splicing, via spliceosome [GO:0000398]" comp133170_c0_seq1,1213,38.3347,0.47225136,55,341,,3.00E-86,Q5XGE0,2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3,2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3,GO:0031418; GO:0016021; GO:0005506; GO:0016706,"L-ascorbic acid binding; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13640;,,,,,,,,,CQ101_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp133174_c0_seq1,390,36.1538,0.54854457,0,29,,,,,,,,,2.00E-13,CHOYP_contig_041133,,,,,,,,, comp133175_c0_seq1,1097,45.7612,0.50933388,207,192,,2.00E-137,Q99PV0,Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8),Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8),GO:0030623; GO:0017070; GO:0071013; GO:0000398; GO:0016607,"U5 snRNA binding; U6 snRNA binding; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nuclear speck",PF01398;PF08082;PF08083;PF08084;PF12134;PF10598;PF10597;PF10596;,0,CHOYP_PRP8.1.1,,,,,,,PRP8_MOUSE,Mus musculus (Mouse),"cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp133179_c1_seq3,881,43.4733,0.55517313,7,6,,7.00E-20,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp133179_c1_seq4,1211,39.7192,0.54534164,0,0,,2.00E-13,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp133179_c1_seq5,1217,39.2769,0.46911796,0,0,,,,,,,,,,,7.00E-30,ruditapes_lrc8617,,,,,,, comp133179_c1_seq6,1223,39.5748,0.54374011,0,0,,8.00E-15,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp133182_c0_seq2,918,43.1373,0.58937803,90,31,,3.00E-40,Q3TVW5,Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin),Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin),GO:0045179; GO:0006915; GO:0005813; GO:0045095; GO:0005739; GO:0030308; GO:0005886,apical cortex; apoptotic process; centrosome; keratin filament; mitochondrion; negative regulation of cell growth; plasma membrane,,2.00E-38,CHOYP_LOC100377118.1.1,,,,,,,TCHP_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell projection organization [GO:0030030]; negative regulation of cell growth [GO:0030308]; negative regulation of cilium assembly [GO:1902018] comp133192_c0_seq1,1085,37.6959,0.34007833,70,230,,3.00E-48,Q7TMY4,THO complex subunit 7 homolog (Ngg1-interacting factor 3-like protein 1-binding protein 1),THO complex subunit 7 homolog (Ngg1-interacting factor 3-like protein 1-binding protein 1),GO:0003723; GO:0008380; GO:0000445; GO:0005737; GO:0046784; GO:0006397,RNA binding; RNA splicing; THO complex part of transcription export complex; cytoplasm; intronless viral mRNA export from host nucleus; mRNA processing,PF05615;,3.00E-23,CHOYP_THOC7.1.1,6.00E-55,ruditapes_c16497,,,,,THOC7_MOUSE,Mus musculus (Mouse),mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription elongation from RNA polymerase II promoter [GO:0006368]; viral mRNA export from host cell nucleus [GO:0046784] comp133193_c1_seq2,1100,42.6364,0.76922292,40,32,,2.00E-13,O14639,Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin),Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin),GO:0003779; GO:0015629; GO:0007411; GO:0005737; GO:0007010; GO:0009887; GO:0007601; GO:0008270,actin binding; actin cytoskeleton; axon guidance; cytoplasm; cytoskeleton organization; organ morphogenesis; visual perception; zinc ion binding,PF16182;PF00412;PF02209;,8.00E-50,CHOYP_LOC100165685.1.1,,,,,,,ABLM1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; organ morphogenesis [GO:0009887]; visual perception [GO:0007601] comp133194_c0_seq1,853,34.5838,0.35722302,91,343,,5.00E-16,Q9BW72,"HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b)","HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b)",GO:0016021; GO:0005743; GO:0043066; GO:0055114; GO:0070469,integral to membrane; mitochondrial inner membrane; negative regulation of apoptotic process; oxidation-reduction process; respiratory chain,PF04588;,,,,,,,,,HIG2A_HUMAN,Homo sapiens (Human),negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114] comp133198_c0_seq1,1034,39.4584,0.37327822,207,1730,,5.00E-66,Q9R088,"Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)","Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)",GO:0005524; GO:0009262; GO:0006264; GO:0005743; GO:0016773; GO:0004797,"ATP binding; deoxyribonucleotide metabolic process; mitochondrial DNA replication; mitochondrial inner membrane; phosphotransferase activity, alcohol group as acceptor; thymidine kinase activity",PF01712;,2.00E-37,CHOYP_TK2.1.1,,,,,,,KITM_MOUSE,Mus musculus (Mouse),deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264] comp133201_c1_seq3,982,42.5662,0.98944391,8,124,,3.00E-13,Q8NBI5,Solute carrier family 43 member 3 (Protein FOAP-13),Solute carrier family 43 member 3 (Protein FOAP-13),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S43A3_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp133204_c2_seq4,1850,36.2703,0.42026168,0,0,,9.00E-80,Q5E951,Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B),Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B),GO:0030154; GO:0005829; GO:0005874; GO:0007399; GO:0007023,cell differentiation; cytosol; microtubule; nervous system development; post-chaperonin tubulin folding pathway,PF01302;PF14560;,3.00E-77,CHOYP_BRAFLDRAFT_275787.1.2,,,,,,,TBCB_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; nervous system development [GO:0007399]; post-chaperonin tubulin folding pathway [GO:0007023] comp133205_c0_seq1,1400,39.2143,0.3967235,27,19,,4.00E-71,Q05086,Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54),Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54),GO:0030521; GO:0007420; GO:0005737; GO:0005829; GO:0019048; GO:0005634; GO:0001541; GO:0014068; GO:0045944; GO:0060736; GO:0000502; GO:0070936; GO:0042787; GO:0035037; GO:0003713; GO:0004842,androgen receptor signaling pathway; brain development; cytoplasm; cytosol; modulation by virus of host morphology or physiology; nucleus; ovarian follicle development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of transcription from RNA polymerase II promoter; prostate gland growth; proteasome complex; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sperm entry; transcription coactivator activity; ubiquitin-protein ligase activity,PF16558;PF00632;,3.00E-76,CHOYP_HERC4.1.1,,,,,,,UBE3A_HUMAN,Homo sapiens (Human),androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032] comp133205_c0_seq3,1279,39.2494,0.33190199,0,0,,1.00E-115,Q5PQN1,Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),GO:0030154; GO:0005737; GO:0005829; GO:0005634; GO:0042787; GO:0007283; GO:0004842,cell differentiation; cytoplasm; cytosol; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity,PF00632;PF00415;,2.00E-76,CHOYP_HERC4.1.1,,,,,,,HERC4_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp133205_c1_seq1,725,43.5862,0.42237447,54,957,,,,,,,,,,,2.00E-27,ruditapes_c21154,,,,,,, comp133209_c0_seq1,939,41.7465,0.44896169,999,2910,,1.00E-20,A9X1A9,"39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9)","39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF01281;,,,,,,,,,RM09_PAPAN,Papio anubis (Olive baboon),translation [GO:0006412] comp133211_c0_seq6,2203,41.2619,0.32475449,0,0,,7.00E-82,O43292,Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1),Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1),GO:0006501; GO:0042765; GO:0016255; GO:0006461; GO:0006621; GO:0015631,C-terminal protein lipidation; GPI-anchor transamidase complex; attachment of GPI anchor to protein; protein complex assembly; protein retention in ER lumen; tubulin binding,PF04114;,,,,,,,,,GPAA1_HUMAN,Homo sapiens (Human),attachment of GPI anchor to protein [GO:0016255]; protein complex assembly [GO:0006461]; protein retention in ER lumen [GO:0006621] comp133211_c0_seq9,1550,43.3548,0.30483776,0,0,,4.00E-35,P39012,GPI transamidase component GAA1,GPI transamidase component GAA1,GO:0042765; GO:0016255,GPI-anchor transamidase complex; attachment of GPI anchor to protein,PF04114;,8.00E-102,CHOYP_LOC664158.1.2,,,,,,,GAA1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),attachment of GPI anchor to protein [GO:0016255] comp133214_c0_seq1,2490,43.012,0.62922147,252,143,,5.00E-96,P97742,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0042755; GO:0006635; GO:0006006; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006810; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; eating behavior; fatty acid beta-oxidation; glucose metabolic process; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; transport; triglyceride metabolic process,PF00755;PF16484;,1.00E-52,CHOYP_CPT1A.1.1,,,,,,,CPT1A_MOUSE,Mus musculus (Mouse),carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641] comp133221_c1_seq1,278,34.8921,1.11999665,6,28,,8.00E-10,Q99J27,Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1),Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1),GO:0015876; GO:0008521; GO:0005789; GO:0016021,acetyl-CoA transport; acetyl-CoA transporter activity; endoplasmic reticulum membrane; integral to membrane,PF13000;,,,,,,,,,ACATN_MOUSE,Mus musculus (Mouse),BMP signaling pathway [GO:0030509]; SMAD protein signal transduction [GO:0060395] comp133223_c1_seq1,3058,38.2276,0.96018891,1742,17,male>female,2.00E-09,P82279,Protein crumbs homolog 1,Protein crumbs homolog 1,GO:0016324; GO:0005509; GO:0007267; GO:0007163; GO:0005576; GO:0042462; GO:0016021; GO:0005902; GO:0007009,apical plasma membrane; calcium ion binding; cell-cell signaling; establishment or maintenance of cell polarity; extracellular region; eye photoreceptor cell development; integral to membrane; microvillus; plasma membrane organization,PF00008;PF12661;PF02210;,,,,,,,,,CRUM1_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; plasma membrane organization [GO:0007009] comp133223_c1_seq2,3293,37.5949,0.93926933,259,606,,2.00E-09,P82279,Protein crumbs homolog 1,Protein crumbs homolog 1,GO:0016324; GO:0005509; GO:0007267; GO:0007163; GO:0005576; GO:0042462; GO:0016021; GO:0005902; GO:0007009,apical plasma membrane; calcium ion binding; cell-cell signaling; establishment or maintenance of cell polarity; extracellular region; eye photoreceptor cell development; integral to membrane; microvillus; plasma membrane organization,PF00008;PF12661;PF02210;,,,,,,,,,CRUM1_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; plasma membrane organization [GO:0007009] comp133224_c0_seq2,266,45.8647,0.85578133,0,5,,4.00E-16,P33420,Protein NIP100 (Protein NIP80),Protein NIP100 (Protein NIP80),GO:0005737; GO:0005869; GO:0030286; GO:0000132; GO:0005874; GO:0008017; GO:0003774; GO:0000922,cytoplasm; dynactin complex; dynein complex; establishment of mitotic spindle orientation; microtubule; microtubule binding; motor activity; spindle pole,PF01302;,,,,,,,,,NIP80_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),establishment of mitotic spindle orientation [GO:0000132] comp133224_c0_seq3,1337,45.5497,0.60612239,0,0,,5.00E-117,Q8N3C7,CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),,,PF12796;PF01302;,2.00E-129,CHOYP_LOC100374091.1.1,,,,,,,CLIP4_HUMAN,Homo sapiens (Human), comp133224_c0_seq4,930,44.5161,0.76730858,64,89,,2.00E-33,O42184,CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 170) (CLIP-170) (Restin),CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 170) (CLIP-170) (Restin),GO:0005813; GO:0005881; GO:0030659; GO:0044354; GO:0001578; GO:0003676; GO:0031116; GO:0001726; GO:0006810; GO:0008270,centrosome; cytoplasmic microtubule; cytoplasmic vesicle membrane; macropinosome; microtubule bundle formation; nucleic acid binding; positive regulation of microtubule polymerization; ruffle; transport; zinc ion binding,PF01302;PF16641;,,,,,,,,,CLIP1_CHICK,Gallus gallus (Chicken),transport [GO:0006810] comp133224_c0_seq5,1385,45.7762,0.59317459,0,0,,7.00E-114,Q5U243,CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59),CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59),GO:0005795,Golgi stack,PF12796;PF01302;,,,,,,,,,CLIP3_XENLA,Xenopus laevis (African clawed frog), comp133231_c0_seq1,1303,40.5219,0.75151882,495,790,,6.00E-50,Q922M5,Cell division cycle-associated 7-like protein (Transcription factor RAM2),Cell division cycle-associated 7-like protein (Transcription factor RAM2),GO:0005737; GO:0005730; GO:0005634; GO:0008284; GO:0006355; GO:0006351,"cytoplasm; nucleolus; nucleus; positive regulation of cell proliferation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10497;,3.00E-55,CHOYP_BRAFLDRAFT_126227.1.1,,,,,,,CDA7L_MOUSE,Mus musculus (Mouse),"positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133232_c0_seq1,1105,38.4615,0.51457859,622,242,,4.00E-49,Q8N0W5,IQ domain-containing protein K,IQ domain-containing protein K,,,,2.00E-69,CHOYP_LOC658706.1.1,2.00E-99,ruditapes_c30224,,,,,IQCK_HUMAN,Homo sapiens (Human), comp133241_c0_seq2,1568,42.4107,0.53982964,121,191,,2.00E-116,P53367,Arfaptin-1 (ADP-ribosylation factor-interacting protein 1),Arfaptin-1 (ADP-ribosylation factor-interacting protein 1),GO:0000139; GO:0005829; GO:0006886; GO:0050708,Golgi membrane; cytosol; intracellular protein transport; regulation of protein secretion,PF06456;,1.00E-92,CHOYP_LOC100373374.1.1,,,,,,,ARFP1_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of protein secretion [GO:0050708] comp133242_c0_seq2,782,38.7468,0.57995041,11,71,,1.00E-33,Q8N3J2,Methyltransferase-like protein 4 (EC 2.1.1.-),Methyltransferase-like protein 4 (EC 2.1.1.-),GO:0008168; GO:0003676; GO:0006139,methyltransferase activity; nucleic acid binding; nucleobase-containing compound metabolic process,PF05063;,,,,,,,,,METL4_HUMAN,Homo sapiens (Human), comp133243_c1_seq3,1545,41.9417,0.47163374,78,89,,2.00E-56,Q6ZNG9,KRAB-A domain-containing protein 2,KRAB-A domain-containing protein 2,GO:0015074; GO:0005622; GO:0003676; GO:0006355,"DNA integration; intracellular; nucleic acid binding; regulation of transcription, DNA-dependent",PF01352;,,,,,,,,,KRBA2_HUMAN,Homo sapiens (Human),"DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]" comp133246_c0_seq1,2106,41.0256,0.34134363,80,192,,1.00E-54,Q8VD04,GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein),GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein),GO:0005769,early endosome,,5.00E-24,CHOYP_GRAP1.1.1,,,,,,,GRAP1_MOUSE,Mus musculus (Mouse), comp133251_c0_seq1,2004,40.2695,0.54657213,0,12,,4.00E-41,Q05609,Serine/threonine-protein kinase CTR1 (EC 2.7.11.1),Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1),GO:0005524; GO:0071281; GO:0005789; GO:0009873; GO:0009686; GO:0010105; GO:0046777; GO:0004674; GO:0004712; GO:2000069; GO:2000035; GO:0048510; GO:0009723; GO:0009750; GO:0009744; GO:0010182,ATP binding; cellular response to iron ion; endoplasmic reticulum membrane; ethylene mediated signaling pathway; gibberellin biosynthetic process; negative regulation of ethylene mediated signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; regulation of post-embryonic root development; regulation of stem cell division; regulation of timing of transition from vegetative to reproductive phase; response to ethylene stimulus; response to fructose stimulus; response to sucrose stimulus; sugar mediated signaling pathway,PF07714;,,,,,,,,,CTR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cellular response to iron ion [GO:0071281]; ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] comp133257_c0_seq1,985,41.0152,0.58045586,861,12809,,,,,,,,,,,2.00E-91,ruditapes_lrc35529,,,,,,, comp133257_c0_seq2,898,41.7595,0.5643447,2435,4656,,2.00E-46,P30151,Elongation factor 1-beta (EF-1-beta) (p30),Elongation factor 1-beta (EF-1-beta) (p30),GO:0005853; GO:0003746,eukaryotic translation elongation factor 1 complex; translation elongation factor activity,PF10587;PF00736;,1.00E-53,CHOYP_BRAFLDRAFT_198650.1.1,2.00E-79,ruditapes2_c1190,,,,,EF1B_XENLA,Xenopus laevis (African clawed frog), comp133258_c0_seq2,591,47.0389,0.86239256,7,29,,4.00E-53,Q9UHN6,Transmembrane protein 2,Transmembrane protein 2,GO:0016021; GO:0007275,integral to membrane; multicellular organismal development,PF10162;,,,,,,,,,TMEM2_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp133258_c1_seq1,1829,46.9656,0.90798858,15,0,,7.00E-22,Q8K1S3,Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B),Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B),GO:0033564; GO:0006915; GO:0005829; GO:0016021; GO:2001240; GO:0005886; GO:0007165,anterior/posterior axon guidance; apoptotic process; cytosol; integral to membrane; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; plasma membrane; signal transduction,PF00531;PF07679;PF00090;PF00791;,,,,,,,,,UNC5B_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; anterior/posterior axon guidance [GO:0033564]; axon guidance [GO:0007411]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068] comp133258_c1_seq2,1967,46.9751,0.89606033,10,37,,3.00E-31,Q8BI06,Protein KIAA1199 homolog (Protein 12H19.01.T7),Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) (Protein 12H19.01.T7),GO:0005737,cytoplasm,PF10162;PF13330;,,,,,,,,,K1199_MOUSE,Mus musculus (Mouse),hyaluronan catabolic process [GO:0030214]; positive regulation of cell migration [GO:0030335]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; sensory perception of sound [GO:0007605] comp133259_c0_seq2,1389,37.005,0.803652,6,22,,,,,,,,,,,3.00E-28,ruditapes_c15480,,,,,,, comp133261_c0_seq1,1658,37.3945,0.51855112,0,3,,3.00E-42,Q8BW74,Hepatic leukemia factor,Hepatic leukemia factor,GO:0005634; GO:0048511; GO:0043565; GO:0003700; GO:0035914; GO:0006351,"nucleus; rhythmic process; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription, DNA-dependent",PF07716;,2.00E-20,CHOYP_LOC101078755.1.1,5.00E-27,ruditapes_c28911,,,,,HLF_MOUSE,Mus musculus (Mouse),rhythmic process [GO:0048511]; skeletal muscle cell differentiation [GO:0035914] comp133261_c0_seq3,1781,38.2931,0.53644708,8,35,,1.00E-29,Q16534,Hepatic leukemia factor,Hepatic leukemia factor,GO:0003690; GO:0007275; GO:0005634; GO:0048511; GO:0043565; GO:0003700; GO:0035914; GO:0006366,double-stranded DNA binding; multicellular organismal development; nucleus; rhythmic process; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription from RNA polymerase II promoter,PF07716;,,,,,,,,,HLF_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; rhythmic process [GO:0048511]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366] comp133266_c0_seq1,624,41.3462,0.38580346,33,157,,3.00E-44,B0BML1,Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase),Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase),GO:0005524; GO:0046177; GO:0046316,ATP binding; D-gluconate catabolic process; gluconokinase activity,PF01202;,,,,,,,,,GNTK_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular carbohydrate metabolic process [GO:0044262]; D-gluconate catabolic process [GO:0046177] comp133268_c0_seq3,1583,42.3247,0.39907877,19,90,,2.00E-06,Q96PZ2,Protein FAM111A,Protein FAM111A,GO:0003824; GO:0005737; GO:0051607; GO:0008152; GO:0000087; GO:0019048; GO:0045071; GO:0005634,catalytic activity; cytoplasm; defense response to virus; metabolic process; mitotic M phase; modulation by virus of host morphology or physiology; negative regulation of viral genome replication; nucleus,,,,,,,,,,F111A_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; DNA replication [GO:0006260]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032] comp133269_c0_seq1,608,47.3684,0.30523338,28,71,,4.00E-10,O43040,Cleavage and termination factor 1 (Transcription termination factor ctf1),Cleavage and termination factor 1 (Transcription termination factor ctf1),GO:0003723; GO:0005829; GO:0005847; GO:0006378; GO:0000166,RNA binding; cytosol; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation; nucleotide binding,PF14327;PF14304;PF00076;,,,,,,,,,CTF1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789] comp133269_c0_seq2,3053,37.9627,0.50769236,2211,7573,,4.00E-180,Q24562,Splicing factor U2AF 50 kDa subunit (U2 auxiliary factor 50 kDa subunit) (U2 snRNP auxiliary factor large subunit),Splicing factor U2AF 50 kDa subunit (U2 auxiliary factor 50 kDa subunit) (U2 snRNP auxiliary factor large subunit),GO:0005686; GO:0003729; GO:0000398; GO:0007052; GO:0022008; GO:0051168; GO:0000166; GO:0008187; GO:0071011; GO:0000381,"U2 snRNP; mRNA binding; mRNA splicing, via spliceosome; mitotic spindle organization; neurogenesis; nuclear export; nucleotide binding; poly-pyrimidine tract binding; precatalytic spliceosome; regulation of alternative mRNA splicing, via spliceosome",PF00076;,0,CHOYP_U2AF2.1.1,4.00E-75,ruditapes_c10844,,,,,U2AF2_DROME,Drosophila melanogaster (Fruit fly),"mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; nuclear export [GO:0051168]; positive regulation of RNA export from nucleus [GO:0046833]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]" comp133269_c0_seq3,1974,35.5623,0.45286306,94,273,,4.00E-09,P97343,Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1),Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1),GO:0005524; GO:0003723; GO:0030424; GO:0007050; GO:0032839; GO:0031175; GO:0071598; GO:0005634; GO:0018105; GO:0045948; GO:0046777; GO:0004674; GO:0046825; GO:0043021,ATP binding; RNA binding; axon; cell cycle arrest; dendrite cytoplasm; neuron projection development; neuronal ribonucleoprotein granule; nucleus; peptidyl-serine phosphorylation; positive regulation of translational initiation; protein autophosphorylation; protein serine/threonine kinase activity; regulation of protein export from nucleus; ribonucleoprotein complex binding,PF00069;PF00076;,,,,,,,,,UHMK1_MOUSE,Mus musculus (Mouse),"cell cycle arrest [GO:0007050]; neuron projection development [GO:0031175]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of translational initiation [GO:0045948]; protein autophosphorylation [GO:0046777]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of protein export from nucleus [GO:0046825]" comp133273_c0_seq1,2738,43.6085,0.40737774,18,5,,2.00E-90,Q9NWF9,E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B),E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B),GO:0006915; GO:0005737; GO:0016874; GO:0019048; GO:0005634; GO:0043161; GO:0070936; GO:0050691; GO:0032648; GO:0008270,apoptotic process; cytoplasm; ligase activity; modulation by virus of host morphology or physiology; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; regulation of defense response to virus by host; regulation of interferon-beta production; zinc ion binding,,5.00E-76,CHOYP_BRAFLDRAFT_117374.1.1,,,,,,,RN216_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of type I interferon production [GO:0032480]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]; viral process [GO:0016032] comp133273_c0_seq2,1754,39.2246,0.44054651,0,0,,3.00E-83,P58283,E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1),E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1),GO:0006915; GO:0005737; GO:0016874; GO:0043161; GO:0070936; GO:0050691; GO:0032648; GO:0008270,apoptotic process; cytoplasm; ligase activity; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; regulation of defense response to virus by host; regulation of interferon-beta production; zinc ion binding,,,,,,,,,,RN216_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648] comp133273_c0_seq3,1276,42.4765,0.50067243,12,20,,8.00E-85,Q9NWF9,E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B),E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B),GO:0006915; GO:0005737; GO:0016874; GO:0019048; GO:0005634; GO:0043161; GO:0070936; GO:0050691; GO:0032648; GO:0008270,apoptotic process; cytoplasm; ligase activity; modulation by virus of host morphology or physiology; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; regulation of defense response to virus by host; regulation of interferon-beta production; zinc ion binding,,,,,,,,,,RN216_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of type I interferon production [GO:0032480]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]; viral process [GO:0016032] comp133274_c0_seq1,2598,43.264,0.73521,0,0,,0,P21575,"Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain)","Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain)",GO:0005525; GO:0006184; GO:0003924; GO:0005794; GO:0007032; GO:0042802; GO:0005874; GO:0005543; GO:0005886; GO:0043234; GO:0032403; GO:0031623,GTP binding; GTP catabolic process; GTPase activity; Golgi apparatus; endosome organization; identical protein binding; microtubule; phospholipid binding; plasma membrane; protein complex; protein complex binding; receptor internalization,PF01031;PF00350;PF02212;PF00169;,,,,,,,,,DYN1_RAT,Rattus norvegicus (Rat),"adult locomotory behavior [GO:0008344]; clathrin-mediated endocytosis [GO:0072583]; endosome organization [GO:0007032]; G-protein coupled receptor internalization [GO:0002031]; positive regulation of synaptic vesicle recycling [GO:1903423]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; sensory perception of sound [GO:0007605]; synaptic transmission, GABAergic [GO:0051932]; toxin transport [GO:1901998]" comp133274_c0_seq10,2860,43.3217,0.72757384,0,0,,0,P21575,"Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain)","Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain)",GO:0005525; GO:0006184; GO:0003924; GO:0005794; GO:0007032; GO:0042802; GO:0005874; GO:0005543; GO:0005886; GO:0043234; GO:0032403; GO:0031623,GTP binding; GTP catabolic process; GTPase activity; Golgi apparatus; endosome organization; identical protein binding; microtubule; phospholipid binding; plasma membrane; protein complex; protein complex binding; receptor internalization,PF01031;PF00350;PF02212;PF00169;,,,,,,,,,DYN1_RAT,Rattus norvegicus (Rat),"adult locomotory behavior [GO:0008344]; clathrin-mediated endocytosis [GO:0072583]; endosome organization [GO:0007032]; G-protein coupled receptor internalization [GO:0002031]; positive regulation of synaptic vesicle recycling [GO:1903423]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; sensory perception of sound [GO:0007605]; synaptic transmission, GABAergic [GO:0051932]; toxin transport [GO:1901998]" comp133274_c0_seq2,1113,45.7323,0.73970843,0,0,,,,,,,,,4.00E-47,CHOYP_DYN1.1.3,,,,,,,,, comp133274_c0_seq3,2815,43.2682,0.73326977,0,0,,0,Q08DF4,Dynamin-1 (EC 3.6.5.5),Dynamin-1 (EC 3.6.5.5),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0007032; GO:0005874; GO:0005543; GO:0006898,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; endosome organization; microtubule; phospholipid binding; receptor-mediated endocytosis,PF01031;PF00350;PF02212;PF00169;,0,CHOYP_DYN1.2.3,6.00E-22,ruditapes_c21906,,,,,DYN1_BOVIN,Bos taurus (Bovine),"adult locomotory behavior [GO:0008344]; clathrin-mediated endocytosis [GO:0072583]; endosome organization [GO:0007032]; negative regulation of exocytosis [GO:0045920]; protein tetramerization [GO:0051262]; sensory perception of sound [GO:0007605]; synaptic transmission, GABAergic [GO:0051932]; toxin transport [GO:1901998]" comp133274_c0_seq6,2553,43.2041,0.74168246,0,0,,9.00E-07,Q55AX0,Dynamin-like protein C (EC 3.6.5.5),Dynamin-like protein C (EC 3.6.5.5),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0000281,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; mitotic cytokinesis,PF00350;,0,CHOYP_DYN1.2.3,,,,,,,DLPC_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281] comp133274_c0_seq7,1158,45.7686,0.72643929,0,0,,7.00E-16,Q6PK57,Putative GED domain-containing protein DNM1P34 (DNM1 pseudogene 34),Putative GED domain-containing protein DNM1P34 (DNM1 pseudogene 34),GO:0005525; GO:0006184; GO:0003924; GO:0005874,GTP binding; GTP catabolic process; GTPase activity; microtubule,PF02212;,4.00E-47,CHOYP_DYN1.1.3,,,,,,,DMP34_HUMAN,Homo sapiens (Human), comp133274_c0_seq9,2386,43.378,0.71623621,0,0,,6.00E-15,Q6PK57,Putative GED domain-containing protein DNM1P34 (DNM1 pseudogene 34),Putative GED domain-containing protein DNM1P34 (DNM1 pseudogene 34),GO:0005525; GO:0006184; GO:0003924; GO:0005874,GTP binding; GTP catabolic process; GTPase activity; microtubule,PF02212;,,,,,,,,,DMP34_HUMAN,Homo sapiens (Human), comp133275_c0_seq1,2108,43.074,0.52275291,8,9,,0,P69566,Ran-binding protein 9 (RanBP9) (B-cell antigen receptor Ig beta-associated protein 1) (IBAP-1) (Ran-binding protein M) (RanBPM),Ran-binding protein 9 (RanBP9) (B-cell antigen receptor Ig beta-associated protein 1) (IBAP-1) (Ran-binding protein M) (RanBPM),GO:0008536; GO:0005737; GO:0005634,Ran GTPase binding; cytoplasm; nucleus,PF10607;PF08513;PF00622;,3.00E-178,CHOYP_RANB9.2.2,,,,,,,RANB9_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373] comp133275_c0_seq2,2104,42.0627,0.46326257,4,4,,2.00E-17,P18160,Dual specificity protein kinase splA (EC 2.7.10.2) (Non-receptor tyrosine kinase spore lysis A) (Tyrosine-protein kinase 1),Dual specificity protein kinase splA (EC 2.7.10.2) (Non-receptor tyrosine kinase spore lysis A) (Tyrosine-protein kinase 1),GO:0005524; GO:0004715; GO:0004712; GO:0004713; GO:0030587; GO:0030435,ATP binding; non-membrane spanning protein tyrosine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; sorocarp development; sporulation resulting in formation of a cellular spore,PF07714;PF07647;PF00622;,5.00E-157,CHOYP_RANB9.2.2,,,,,,,SPLA_DICDI,Dictyostelium discoideum (Slime mold),anatomical structure morphogenesis [GO:0009653]; sorocarp development [GO:0030587]; sporulation resulting in formation of a cellular spore [GO:0030435] comp133276_c0_seq1,455,44.6154,0.36915782,0,5,,4.00E-10,Q9VKM6,Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1),Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1),GO:0003677; GO:0035267; GO:0016573; GO:0043486; GO:0010629; GO:0006355; GO:0006351,"DNA binding; NuA4 histone acetyltransferase complex; histone acetylation; histone exchange; negative regulation of gene expression; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08265;,,,,,,,,,VPS72_DROME,Drosophila melanogaster (Fruit fly),"histone acetylation [GO:0016573]; histone exchange [GO:0043486]; negative regulation of gene expression [GO:0010629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133276_c0_seq3,908,41.7401,0.44885032,28,217,,4.00E-23,Q6GNJ8,Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1),Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1),GO:0003677; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08265;,4.00E-72,CHOYP_BRAFLDRAFT_167661.1.1,,,,,,,VPS72_XENLA,Xenopus laevis (African clawed frog),"histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133277_c0_seq8,1086,34.1621,0.48296842,46,302,,4.00E-53,Q90YG6,Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma),Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma),GO:0006355; GO:0005672; GO:0006367,"regulation of transcription, DNA-dependent; transcription factor TFIIA complex; transcription initiation from RNA polymerase II promoter",PF02751;PF02268;,5.00E-46,CHOYP_T2AG.1.1,,,,,,,T2AG_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),"regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp133285_c0_seq2,689,37.0102,0.53613167,0,16,,3.00E-31,Q99547,M-phase phosphoprotein 6,M-phase phosphoprotein 6,GO:0003723; GO:0005737; GO:0000178; GO:0000460; GO:0000087; GO:0005730,RNA binding; cytoplasm; exosome (RNase complex); maturation of 5.8S rRNA; mitotic M phase; nucleolus,PF10175;,2.00E-23,CHOYP_MPH6.1.1,,,,,,,MPH6_HUMAN,Homo sapiens (Human),maturation of 5.8S rRNA [GO:0000460]; rRNA processing [GO:0006364] comp133286_c0_seq5,1286,43.6236,0.48164954,82,145,,6.00E-72,Q9H7B4,Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.43) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1),Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.43) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1),GO:0005737; GO:0018024; GO:0046872; GO:0005634,cytoplasm; histone-lysine N-methyltransferase activity; metal ion binding; nucleus,PF00856;PF01753;,,,,,,,,,SMYD3_HUMAN,Homo sapiens (Human),cellular response to dexamethasone stimulus [GO:0071549]; establishment of protein localization [GO:0045184]; myotube cell development [GO:0014904]; negative regulation of protein kinase activity [GO:0006469]; nucleosome assembly [GO:0006334]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp133292_c2_seq1,944,40.572,0.649646,27,91,,1.00E-22,Q5RE08,F-box only protein 22,F-box only protein 22,GO:0030018,Z disc,PF00646;PF10442;,,,,,,,,,FBX22_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp133293_c0_seq1,2591,36.3566,0.42352947,409,2930,,5.00E-150,Q58D31,Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase),Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase),GO:0003939; GO:0051160; GO:0051287; GO:0046370; GO:0031966; GO:0031514; GO:0006062; GO:0030317; GO:0008270,L-iditol 2-dehydrogenase activity; L-xylitol catabolic process; NAD binding; fructose biosynthetic process; mitochondrial membrane; motile cilium; sorbitol catabolic process; sperm motility; zinc ion binding,PF08240;PF00107;,6.00E-151,CHOYP_LOC100370478.2.2,5.00E-16,ruditapes_c13109,,,,,DHSO_BOVIN,Bos taurus (Bovine),fructose biosynthetic process [GO:0046370]; L-xylitol catabolic process [GO:0051160]; sorbitol catabolic process [GO:0006062]; sperm motility [GO:0030317] comp133299_c0_seq1,614,40.8795,0.56481388,504,1013,,2.00E-74,Q9Y3B2,Exosome complex component CSL4 (Exosome component 1),Exosome complex component CSL4 (Exosome component 1),GO:0003723; GO:0005829; GO:0043928; GO:0000178; GO:0010467; GO:0005730; GO:0006364,RNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; exosome (RNase complex); gene expression; nucleolus; rRNA processing,PF14382;PF10447;,3.00E-59,CHOYP_NEMVEDRAFT_V1G238196.1.2,,,,,,,EXOS1_HUMAN,Homo sapiens (Human),exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; regulation of mRNA stability [GO:0043488]; rRNA processing [GO:0006364] comp133305_c0_seq1,1220,34.8361,0.16391473,106,803,,6.00E-74,Q8BG94,COMM domain-containing protein 7,COMM domain-containing protein 7,GO:0032088; GO:0045892; GO:0033209,"negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription, DNA-dependent; tumor necrosis factor-mediated signaling pathway",PF07258;,2.00E-52,CHOYP_BRAFLDRAFT_108193.2.2,,,,,,,COMD7_MOUSE,Mus musculus (Mouse),"negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp133310_c0_seq1,1407,41.5778,0.8277488,13,2,,2.00E-38,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp133310_c0_seq2,1727,41.9803,0.76565343,2,12,,2.00E-63,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp133315_c1_seq1,777,41.184,0.48948215,51,83,,1.00E-48,A8E7I5,Tetratricopeptide repeat protein 36 (TPR repeat protein 36),Tetratricopeptide repeat protein 36 (TPR repeat protein 36),,,,4.00E-14,CHOYP_BRAFLDRAFT_122687.1.1,,,,,,,TTC36_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp133324_c0_seq1,1536,45.9635,0.67609999,73,25,,1.00E-21,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp133325_c0_seq1,1909,41.4877,0.97423839,102,46,,,,,,,,,3.00E-57,CHOYP_LOC100888507.1.1,,,,,,,,, comp133327_c0_seq2,609,44.335,0.97256846,0,266,,4.00E-07,Q07079,Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5),Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5),GO:0071320; GO:0001968; GO:0042593; GO:0006006; GO:0031069; GO:0016942; GO:0035556; GO:0060056; GO:0043569; GO:0045668; GO:0014912; GO:0048662; GO:0017148; GO:0001649; GO:0043568; GO:0051897; GO:0001558; GO:0010906; GO:0048630; GO:0051146; GO:0044342,cellular response to cAMP; fibronectin binding; glucose homeostasis; glucose metabolic process; hair follicle morphogenesis; insulin-like growth factor binding protein complex; intracellular signal transduction; mammary gland involution; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of osteoblast differentiation; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of translation; osteoblast differentiation; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of protein kinase B signaling cascade; regulation of cell growth; regulation of glucose metabolic process; skeletal muscle tissue growth; striated muscle cell differentiation; type B pancreatic cell proliferation,PF00219;PF00086;,,,,,,,,,IBP5_MOUSE,Mus musculus (Mouse),cellular response to cAMP [GO:0071320]; cellular response to organic cyclic compound [GO:0071407]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; hair follicle morphogenesis [GO:0031069]; intracellular signal transduction [GO:0035556]; lung alveolus development [GO:0048286]; mammary gland involution [GO:0060056]; negative regulation of cell migration [GO:0030336]; negative regulation of growth [GO:0045926]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of skeletal muscle hypertrophy [GO:1904205]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cell growth [GO:0001558]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of insulin-like growth factor receptor signaling pathway [GO:0043567]; response to growth hormone [GO:0060416]; skeletal muscle tissue growth [GO:0048630]; striated muscle cell differentiation [GO:0051146]; type B pancreatic cell proliferation [GO:0044342] comp133332_c0_seq2,1417,37.7558,0.63751858,141,141,,1.00E-103,Q5RK30,Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein homolog),Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein homolog),GO:0003723; GO:0008283; GO:0005737; GO:0042256; GO:0005730; GO:0005654; GO:0005634; GO:0006364; GO:0042273; GO:0043022; GO:0000922,RNA binding; cell proliferation; cytoplasm; mature ribosome assembly; nucleolus; nucleoplasm; nucleus; rRNA processing; ribosomal large subunit biogenesis; ribosome binding; spindle pole,PF01172;PF09377;,3.00E-114,CHOYP_SBDS.1.1,,,,,,,SBDS_RAT,Rattus norvegicus (Rat),bone marrow development [GO:0048539]; bone mineralization [GO:0030282]; cell proliferation [GO:0008283]; inner cell mass cell proliferation [GO:0001833]; leukocyte chemotaxis [GO:0030595]; mature ribosome assembly [GO:0042256]; rRNA processing [GO:0006364] comp133335_c0_seq1,899,43.9377,0.56470658,3,0,,5.00E-08,P17713,Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK),Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK),GO:0005524; GO:0004715; GO:0018108,ATP binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF07714;PF00017;PF00018;,,,,,,,,,STK_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata),innate immune response [GO:0045087] comp133335_c0_seq2,1023,44.9658,0.60784372,13,23,,5.00E-116,P19174,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0038095; GO:0038096; GO:0050852; GO:0000186; GO:0007202; GO:0007411; GO:0007596; GO:0005509; GO:0071364; GO:0019221; GO:0005829; GO:0007173; GO:0008543; GO:0001701; GO:0045087; GO:0043647; GO:0035556; GO:0030027; GO:0050900; GO:0019048; GO:0048011; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0045766; GO:0043536; GO:0005057; GO:0001726,COP9 signalosome; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell receptor signaling pathway; activation of MAPKK activity; activation of phospholipase C activity; axon guidance; blood coagulation; calcium ion binding; cellular response to epidermal growth factor stimulus; cytokine-mediated signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; in utero embryonic development; innate immune response; inositol phosphate metabolic process; intracellular signal transduction; lamellipodium; leukocyte migration; modulation by virus of host morphology or physiology; neurotrophin TRK receptor signaling pathway; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; receptor signaling protein activity; ruffle,PF00168;PF00388;PF00387;PF00017;PF00018;,6.00E-45,CHOYP_LOC100377901.1.1,,,,,,,PLCG1_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032] comp133335_c1_seq1,350,49.1429,0.57580784,16,5,,9.00E-08,O43639,Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta),Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta),GO:0042110; GO:0007015; GO:0007411; GO:0016477; GO:0008093; GO:0005829; GO:0005783; GO:0007173; GO:0030032; GO:0008285; GO:0042102; GO:0030838; GO:0045944; GO:0030159; GO:0007176; GO:0006417; GO:0007172; GO:0012506,T cell activation; actin filament organization; axon guidance; cell migration; cytoskeletal adaptor activity; cytosol; endoplasmic reticulum; epidermal growth factor receptor signaling pathway; lamellipodium assembly; negative regulation of cell proliferation; positive regulation of T cell proliferation; positive regulation of actin filament polymerization; positive regulation of transcription from RNA polymerase II promoter; receptor signaling complex scaffold activity; regulation of epidermal growth factor-activated receptor activity; regulation of translation; signal complex assembly; vesicle membrane,PF00017;PF00018;PF14604;,,,,,,,,,NCK2_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192] comp133336_c0_seq1,1035,38.0676,0.5433619,4951,22301,,3.00E-82,P25007,Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase),Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase),GO:0005829; GO:0005875; GO:0042277; GO:0003755; GO:0006457; GO:0035071,cytosol; microtubule associated complex; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; salivary gland cell autophagic cell death,PF00160;,5.00E-46,CHOYP_PHATRDRAFT_43152.1.1,5.00E-107,ruditapes_lrc32168,,,,,PPIA_DROME,Drosophila melanogaster (Fruit fly),autophagic cell death [GO:0048102]; protein folding [GO:0006457]; salivary gland cell autophagic cell death [GO:0035071] comp133336_c0_seq2,1321,34.7464,0.48001098,1423,6225,,,,,,,,,8.00E-51,CHOYP_PPIE.1.1,4.00E-115,ruditapes_lrc25599,,,,,,, comp133336_c0_seq3,1306,35.2986,0.445366,1049,11613,,1.00E-32,P28517,"Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme (PPIase) (EC 5.2.1.8) (Rotamase)","Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme (PPIase) (EC 5.2.1.8) (Rotamase)",GO:0016021; GO:0003755; GO:0006457; GO:0000413; GO:0050896; GO:0007601,integral to membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; response to stimulus; visual perception,PF00160;,5.00E-72,CHOYP_LOC101156984.2.2,7.00E-106,ruditapes2_lrc3825,,,,,CYPR_CALVI,Calliphora vicina (Blue blowfly) (Calliphora erythrocephala),protein folding [GO:0006457]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp133338_c0_seq1,1108,39.9819,0.85361002,278,699,,1.00E-39,P35521,"Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln))","Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln))",GO:0006884; GO:0006821; GO:0005737; GO:0005634,cell volume homeostasis; chloride transport; cytoplasm; nucleus,,6.00E-20,CHOYP_LOC101062323.1.1,,,,,,,ICLN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cell volume homeostasis [GO:0006884]; chloride transport [GO:0006821]; spliceosomal snRNP assembly [GO:0000387] comp133339_c0_seq1,808,46.7822,0.83104707,4,769,female>male,1.00E-100,Q96WV0,Uncharacterized urease accessory protein ureG-like,Uncharacterized urease accessory protein ureG-like,GO:0005524; GO:0005525; GO:0003924; GO:0005829; GO:0016530; GO:0016151; GO:0005634; GO:0019627,ATP binding; GTP binding; GTPase activity; cytosol; metallochaperone activity; nickel cation binding; nucleus; urea metabolic process,PF02492;,,,5.00E-48,ruditapes2_c1101,,,,,UREG_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),urea metabolic process [GO:0019627] comp133340_c0_seq1,756,43.1217,0.43684915,66,162,,2.00E-16,Q1T7B9,Centromere protein M (CENP-M),Centromere protein M (CENP-M),GO:0000775; GO:0005634,"chromosome, centromeric region; nucleus",PF11111;,,,,,,,,,CENPM_CHICK,Gallus gallus (Chicken), comp133344_c0_seq1,1322,33.8124,0.30122968,20,258,,2.00E-38,Q6AXQ2,EF-hand calcium-binding domain-containing protein 11,EF-hand calcium-binding domain-containing protein 11,GO:0005509,calcium ion binding,PF13499;PF13833;,,,7.00E-24,ruditapes_c22987,,,,,EFC11_RAT,Rattus norvegicus (Rat), comp133344_c0_seq2,1226,33.6868,0.32791567,0,17,,5.00E-07,Q9LIK5,Calmodulin-like protein 11,Calmodulin-like protein 11,GO:0005509,calcium ion binding,PF13499;,3.00E-11,CHOYP_LOC100369388.1.1,,,,,,,CML11_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp133345_c1_seq2,1478,39.3099,0.2634549,88,167,,8.00E-41,Q95LM1,Ubiquitin-conjugating enzyme E2 U (EC 6.3.2.19) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U),Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U),GO:0005524; GO:0004842,ATP binding; ubiquitin-protein ligase activity,PF00179;,1.00E-62,CHOYP_LOC100370245.1.1,,,7.00E-64,AM859011.p.cg.6,7,,UBE2U_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein ubiquitination [GO:0016567] comp133347_c0_seq1,784,34.8214,0.64134091,4383,19260,,,,,,,,,1.00E-38,CHOYP_LOC100891402.2.3,6.00E-47,ruditapes_c3838,,,,,,, comp133348_c0_seq1,564,45.2128,0.61350474,0,0,,,,,,,,,8.00E-78,CHOYP_ACACA.1.7,,,,,,,,, comp133348_c0_seq2,1846,46.208,0.43115363,59,31,,0,P11029,Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)],Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)],GO:0005524; GO:0003989; GO:0004075; GO:0005737; GO:0006633; GO:2001295; GO:0046872,ATP binding; acetyl-CoA carboxylase activity; biotin carboxylase activity; cytoplasm; fatty acid biosynthetic process; malonyl-CoA biosynthetic process; metal ion binding,PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;,0,CHOYP_ACAC.1.2,4.00E-16,ruditapes_c18315,,,,,ACAC_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295] comp133348_c1_seq4,1240,44.8387,0.51465114,82,3,,,,,,,,,2.00E-109,CHOYP_ACAC.1.2,,,,,,,,, comp133351_c0_seq1,1203,43.4746,0.79721076,51,283,,0,P30162,Actin-1,Actin-1,GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,7.00E-127,CHOYP_LOC752782.1.1,1.00E-89,ruditapes_lrc28735,,,,,ACT1_ONCVO,Onchocerca volvulus, comp133356_c0_seq1,944,38.1356,0.29224427,10601,30649,,3.00E-43,Q9D3D9,"ATP synthase subunit delta, mitochondrial (F-ATPase delta subunit)","ATP synthase subunit delta, mitochondrial (F-ATPase delta subunit)",GO:0006200; GO:0015986; GO:0005753; GO:0046933; GO:0045261; GO:0046961,"ATP catabolic process; ATP synthesis coupled proton transport; mitochondrial proton-transporting ATP synthase complex; proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATP synthase complex, catalytic core F(1); proton-transporting ATPase activity, rotational mechanism",PF02823;,,,2.00E-23,ruditapes2_c1564,,,,,ATPD_MOUSE,Mus musculus (Mouse),ATP synthesis coupled proton transport [GO:0015986]; proton transport [GO:0015992] comp133357_c0_seq11,1132,42.6678,0.27295588,0,0,,6.00E-113,Q8C0L8,Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5),Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5),GO:0000139; GO:0017119; GO:0005829; GO:0006891; GO:0015031,Golgi membrane; Golgi transport complex; cytosol; intra-Golgi vesicle-mediated transport; protein transport,PF10392;,,,,,,,,,COG5_MOUSE,Mus musculus (Mouse),inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp133357_c0_seq2,1096,42.6095,0.26272083,0,0,,9.00E-108,Q8C0L8,Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5),Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5),GO:0000139; GO:0017119; GO:0005829; GO:0006891; GO:0015031,Golgi membrane; Golgi transport complex; cytosol; intra-Golgi vesicle-mediated transport; protein transport,PF10392;,,,,,,,,,COG5_MOUSE,Mus musculus (Mouse),inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp133357_c0_seq9,636,42.9245,0.45575237,51,39,,5.00E-25,Q54HE0,Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5),Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5),GO:0000139; GO:0017119; GO:0006891; GO:0015031,Golgi membrane; Golgi transport complex; intra-Golgi vesicle-mediated transport; protein transport,PF10392;,2.00E-80,CHOYP_COG5.1.1,,,,,,,COG5_DICDI,Dictyostelium discoideum (Slime mold),intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp133360_c0_seq1,884,40.8371,1.03459848,22,102,,3.00E-13,P02517,Heat shock protein 26,Heat shock protein 26,GO:0009631; GO:0008340; GO:0005875,cold acclimation; determination of adult lifespan; microtubule associated complex,PF00011;,,,,,,,,,HSP26_DROME,Drosophila melanogaster (Fruit fly),chaperone-mediated protein folding [GO:0061077]; cold acclimation [GO:0009631]; determination of adult lifespan [GO:0008340]; protein refolding [GO:0042026]; response to heat [GO:0009408] comp133360_c0_seq2,864,40.8565,1.03249475,4,32,,4.00E-25,Q5ENY9,Alpha-crystallin B chain (Alpha(B)-crystallin),Alpha-crystallin B chain (Alpha(B)-crystallin),GO:0005737; GO:0046872; GO:0005634; GO:0042803; GO:0005212,cytoplasm; metal ion binding; nucleus; protein homodimerization activity; structural constituent of eye lens,PF00525;PF00011;,,,,,,,,,CRYAB_SHEEP,Ovis aries (Sheep), comp133362_c0_seq1,1044,35.728,0.42479714,45,1690,,3.00E-45,P0AF48,UPF0047 protein YjbQ,UPF0047 protein YjbQ,,,PF01894;,2.00E-32,CHOYP_LOC100199222.1.1,,,,,,,YJBQ_ECOLI,Escherichia coli (strain K12), comp133363_c0_seq1,2235,38.8367,0.26119975,472,1815,,7.00E-20,O15504,Nucleoporin-like protein 2 (NLP-1) (NUP42 homolog) (Nucleoporin hCG1),Nucleoporin-like protein 2 (NLP-1) (NUP42 homolog) (Nucleoporin hCG1),GO:0005975; GO:0019221; GO:0005829; GO:0015758; GO:0051028; GO:0046872; GO:0007077; GO:0005049; GO:0031965; GO:0005643; GO:0005634; GO:0010827; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; cytosol; glucose transport; mRNA transport; metal ion binding; mitotic nuclear envelope disassembly; nuclear export signal receptor activity; nuclear membrane; nuclear pore; nucleus; regulation of glucose transport; small molecule metabolic process; transmembrane transport; viral process,,,,,,,,,,NUPL2_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp133364_c0_seq1,1475,42.8475,0.52664869,105,199,,9.00E-112,Q7Z5Y7,BTB/POZ domain-containing protein KCTD20,BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20),GO:0051260,protein homooligomerization,,2.00E-91,CHOYP_LOC657718.1.1,,,,,,,KCD20_HUMAN,Homo sapiens (Human),positive regulation of phosphorylation [GO:0042327] comp133366_c0_seq1,668,37.5749,1.32789387,41,382,,,,,,,,,,,4.00E-29,ruditapes_lrc7429,,,,,,, comp133368_c0_seq1,821,40.3167,0.85213011,70,124417,female>male,5.00E-16,Q8IZJ3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,GO:0005615; GO:0010951; GO:0005886; GO:0004867,extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;,,,,,,,,,CPMD8_HUMAN,Homo sapiens (Human), comp133371_c0_seq1,1274,41.9152,0.61934803,170,530,,1.00E-121,Q9BW27,Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1),Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1),GO:0005975; GO:0000777; GO:0019221; GO:0005829; GO:0015758; GO:0030032; GO:0051028; GO:0048246; GO:0007077; GO:0031965; GO:0031080; GO:0015031; GO:0010827; GO:0044281; GO:0005819; GO:0055085; GO:0016032,carbohydrate metabolic process; condensed chromosome kinetochore; cytokine-mediated signaling pathway; cytosol; glucose transport; lamellipodium assembly; mRNA transport; macrophage chemotaxis; mitotic nuclear envelope disassembly; nuclear membrane; nuclear pore outer ring; protein transport; regulation of glucose transport; small molecule metabolic process; spindle; transmembrane transport; viral process,PF07575;,2.00E-64,CHOYP_NUP85.1.1,2.00E-29,ruditapes_c24847,,,,,NUP85_HUMAN,Homo sapiens (Human),"gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; lamellipodium assembly [GO:0030032]; macrophage chemotaxis [GO:0048246]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; positive regulation of transcription, DNA-templated [GO:0045893]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; sister chromatid cohesion [GO:0007062]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]" comp133379_c0_seq1,893,47.7044,0.6122078,0,0,,2.00E-08,Q3MV19,TNF receptor-associated factor 6-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),TNF receptor-associated factor 6-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),GO:0050852; GO:0007250; GO:0046849; GO:0048468; GO:0005737; GO:0070498; GO:0009887; GO:0001503; GO:0043123; GO:0043507; GO:0031666; GO:0045672; GO:0070534; GO:0051865; GO:0042981; GO:0004871; GO:0004842; GO:0008270,T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; bone remodeling; cell development; cytoplasm; interleukin-1-mediated signaling pathway; organ morphogenesis; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of osteoclast differentiation; protein K63-linked ubiquitination; protein autoubiquitination; regulation of apoptotic process; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,TRF6A_XENLA,Xenopus laevis (African clawed frog),activation of NF-kappaB-inducing kinase activity [GO:0007250]; immune response [GO:0006955]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981] comp133379_c0_seq2,1603,43.7929,0.63846785,25,109,,3.00E-157,Q5FWL3,E3 ubiquitin-protein ligase NRDP1 (EC 6.3.2.-) (RING finger protein 41),E3 ubiquitin-protein ligase NRDP1 (EC 6.3.2.-) (RING finger protein 41),GO:0097191; GO:0000209; GO:0031386; GO:0004842; GO:0008270,extrinsic apoptotic signaling pathway; protein polyubiquitination; protein tag; ubiquitin-protein ligase activity; zinc ion binding,PF08941;,6.00E-161,CHOYP_LOC661626.1.1,,,,,,,RNF41_XENLA,Xenopus laevis (African clawed frog),extrinsic apoptotic signaling pathway [GO:0097191]; protein polyubiquitination [GO:0000209] comp133380_c1_seq1,1319,40.4094,0.45660284,72,107,,6.00E-43,O35231,Kinesin-like protein KIFC3,Kinesin-like protein KIFC3,GO:0005524; GO:0005794; GO:0007030; GO:0005813; GO:0030659; GO:0090136; GO:0005871; GO:0005874; GO:0007018; GO:0007017; GO:0008569; GO:0005915; GO:0045218,ATP binding; Golgi apparatus; Golgi organization; centrosome; cytoplasmic vesicle membrane; epithelial cell-cell adhesion; kinesin complex; microtubule; microtubule-based movement; microtubule-based process; minus-end-directed microtubule motor activity; zonula adherens; zonula adherens maintenance,PF00225;,4.00E-23,CHOYP_LOC100375065.1.1,,,,,,,KIFC3_MOUSE,Mus musculus (Mouse),epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218] comp133383_c0_seq1,1339,35.6236,0.37739856,108,241,,3.00E-33,Q3TTL0,Uncharacterized protein C3orf38 homolog,Uncharacterized protein C3orf38 homolog,GO:0006915,apoptotic process,PF15008;,,,,,,,,,CC038_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915] comp133387_c1_seq1,1815,37.9063,0.52353835,3,14,,1.00E-157,Q8CEQ0,Cyclin-dependent kinase-like 1 (EC 2.7.11.22),Cyclin-dependent kinase-like 1 (EC 2.7.11.22),GO:0005524; GO:0004693; GO:0005737; GO:0007507; GO:0005634,ATP binding; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; heart development; nucleus,PF00069;,,,,,,,,,CDKL1_MOUSE,Mus musculus (Mouse),heart development [GO:0007507] comp133387_c1_seq2,1830,37.8142,0.52175751,8,18,,5.00E-147,Q5MAI5,Cyclin-dependent kinase-like 4 (EC 2.7.11.22),Cyclin-dependent kinase-like 4 (EC 2.7.11.22),GO:0005524; GO:0004693; GO:0005737,ATP binding; cyclin-dependent protein serine/threonine kinase activity; cytoplasm,PF00069;,1.00E-163,CHOYP_LOC100180636.1.1,,,,,,,CDKL4_HUMAN,Homo sapiens (Human), comp133389_c0_seq3,1653,43.7387,0.43068974,104,138,,3.00E-29,Q9ULU4,Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8),Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8),GO:0001106; GO:0005634; GO:0070491; GO:0008270,RNA polymerase II transcription corepressor activity; nucleus; repressing transcription factor binding; zinc ion binding,PF00439;PF12064;PF00855;,4.00E-18,CHOYP_PKCB1.1.1,,,,,,,PKCB1_HUMAN,Homo sapiens (Human),"modulation of excitatory postsynaptic potential [GO:0098815]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of filopodium assembly [GO:0051491]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of transcription, DNA-templated [GO:0006355]" comp133390_c0_seq1,838,41.8854,0.73339265,28,278,,4.00E-43,Q9MYP6,17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),GO:0005813; GO:0005829; GO:0004303; GO:0006706; GO:0047045,centrosome; cytosol; estradiol 17-beta-dehydrogenase activity; steroid catabolic process; testosterone 17-beta-dehydrogenase (NADP+) activity,,,,5.00E-11,ruditapes_c7690,,,,,DHB14_BOVIN,Bos taurus (Bovine),steroid catabolic process [GO:0006706] comp133394_c0_seq1,1168,38.0993,0.4752036,5,101,,,,,,,,,3.00E-18,CHOYP_TM241.1.1,,,,,,,,, comp133394_c0_seq2,1246,38.2825,0.48461434,19,117,,3.00E-50,A1L3G4,Transmembrane protein 241,Transmembrane protein 241,GO:0016021,integral to membrane,,,,,,,,,,TM241_XENLA,Xenopus laevis (African clawed frog), comp133396_c1_seq1,1035,28.9855,0.83328198,371,1462,,,,,,,,,,,1.00E-32,ruditapes2_c969,,,,,,, comp133397_c0_seq2,1444,40.7895,0.48681482,0,0,,,,,,,,,8.00E-13,CHOYP_MICA2.1.1,,,,,,,,, comp133397_c0_seq3,2409,39.6845,0.44378395,0,0,,6.00E-16,Q921U8,Smoothelin,Smoothelin,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF00307;PF12510;,,,,,,,,,SMTN_MOUSE,Mus musculus (Mouse), comp133397_c0_seq5,2094,40.4489,0.46813038,0,0,,1.00E-54,Q8IY33,MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2),MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2),GO:0031532; GO:0051015; GO:0032432; GO:0030041; GO:0005829; GO:0032456; GO:0006897; GO:0031005; GO:0043005; GO:0031175; GO:0005886; GO:0055037; GO:0034446; GO:0005923; GO:0070830; GO:0008270,actin cytoskeleton reorganization; actin filament binding; actin filament bundle; actin filament polymerization; cytosol; endocytic recycling; endocytosis; filamin binding; neuron projection; neuron projection development; plasma membrane; recycling endosome; substrate adhesion-dependent cell spreading; tight junction; tight junction assembly; zinc ion binding,PF00307;PF12130;PF00412;,5.00E-43,CHOYP_LOC100372213.1.1,2.00E-77,ruditapes_c28732,,,,,MILK2_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; bicellular tight junction assembly [GO:0070830]; endocytic recycling [GO:0032456]; neuron projection development [GO:0031175]; positive regulation of protein targeting to mitochondrion [GO:1903955]; substrate adhesion-dependent cell spreading [GO:0034446] comp133398_c0_seq1,981,40.5708,0.58452442,43,215,,5.00E-26,Q8C6C7,Protein FAM204A,Protein FAM204A,,,,5.00E-14,CHOYP_FAM204A.1.1,,,,,,,F204A_MOUSE,Mus musculus (Mouse), comp133400_c0_seq2,1109,34.9865,0.9079762,163,595,,2.00E-08,O09111,"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 15.6) (Np15.6) (p15.6)","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 15.6) (Np15.6) (p15.6)",GO:0016021; GO:0005743; GO:0005739; GO:0055114; GO:0070469,integral to membrane; mitochondrial inner membrane; mitochondrion; oxidation-reduction process; respiratory chain,PF10183;,,,,,,,,,NDUBB_MOUSE,Mus musculus (Mouse),oxidation-reduction process [GO:0055114] comp133401_c0_seq1,1282,39.3916,0.44565519,108,2732,,2.00E-145,Q13630,"GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)","GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)",GO:0042351; GO:0042356; GO:0050577; GO:0019673; GO:0050662; GO:0019835; GO:0005737; GO:0009055; GO:0016853; GO:0007159,'de novo' GDP-L-fucose biosynthetic process; GDP-4-dehydro-D-rhamnose reductase activity; GDP-L-fucose synthase activity; GDP-mannose metabolic process; coenzyme binding; cytolysis; cytoplasm; electron carrier activity; isomerase activity; leukocyte cell-cell adhesion,PF01370;,1.00E-104,CHOYP_FCL.1.1,,,,,,,FCL_HUMAN,Homo sapiens (Human),'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; cytolysis [GO:0019835]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159] comp133402_c0_seq1,359,41.5042,0.39215991,8,12,,2.00E-28,Q9ER24,Ataxin-10 (Neuronal beta-catenin-like protein) (Spinocerebellar ataxia type 10 protein homolog),Ataxin-10 (Neuronal beta-catenin-like protein) (Spinocerebellar ataxia type 10 protein homolog),GO:0005829; GO:0030425; GO:0042802; GO:0031175; GO:0043025; GO:0048471,cytosol; dendrite; identical protein binding; neuron projection development; neuronal cell body; perinuclear region of cytoplasm,PF09759;,,,,,,,,,ATX10_RAT,Rattus norvegicus (Rat),cilium assembly [GO:0042384]; neuron projection development [GO:0031175]; protein homotrimerization [GO:0070207] comp133405_c0_seq1,1966,42.5738,0.49421559,0,0,,9.00E-102,O00311,Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1),Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1),GO:0005524; GO:0006260; GO:0000082; GO:0051301; GO:0005737; GO:0016301; GO:0046872; GO:0005654; GO:0008284; GO:0004674,ATP binding; DNA replication; G1/S transition of mitotic cell cycle; cell division; cytoplasm; kinase activity; metal ion binding; nucleoplasm; positive regulation of cell proliferation; protein serine/threonine kinase activity,PF00069;,3.00E-90,CHOYP_LOC100367914.1.1,,,,,,,CDC7_HUMAN,Homo sapiens (Human),cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; G1/S transition of mitotic cell cycle [GO:0000082]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; regulation of cell shape [GO:0008360] comp133405_c0_seq2,2030,42.3645,0.48347736,11,19,,1.00E-99,Q9Z0H0,Cell division cycle 7-related protein kinase (CDC7-related kinase) (muCdc7) (EC 2.7.11.1),Cell division cycle 7-related protein kinase (CDC7-related kinase) (muCdc7) (EC 2.7.11.1),GO:0005524; GO:0007049; GO:0051301; GO:0005737; GO:0046872; GO:0005634; GO:0008284; GO:0004674,ATP binding; cell cycle; cell division; cytoplasm; metal ion binding; nucleus; positive regulation of cell proliferation; protein serine/threonine kinase activity,PF00069;,,,,,,,,,CDC7_MOUSE,Mus musculus (Mouse),cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; regulation of cell shape [GO:0008360] comp133409_c0_seq2,944,42.6907,0.3865035,39,270,,7.00E-29,Q96EV8,Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein),Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein),GO:0031083; GO:0031532; GO:0008089; GO:0048490; GO:0030424; GO:0007596; GO:0030054; GO:0043197; GO:0005789; GO:0010008; GO:0030426; GO:0033162; GO:0032438; GO:0048812; GO:0005634; GO:0060155; GO:0010628; GO:0001956; GO:0006892; GO:0014069; GO:0045211; GO:0060159; GO:0014059; GO:0042383; GO:0016528; GO:0030672,BLOC-1 complex; actin cytoskeleton reorganization; anterograde axon cargo transport; anterograde synaptic vesicle transport; axon; blood coagulation; cell junction; dendritic spine; endoplasmic reticulum membrane; endosome membrane; growth cone; melanosome membrane; melanosome organization; neuron projection morphogenesis; nucleus; platelet dense granule organization; positive regulation of gene expression; positive regulation of neurotransmitter secretion; post-Golgi vesicle-mediated transport; postsynaptic density; postsynaptic membrane; regulation of dopamine receptor signaling pathway; regulation of dopamine secretion; sarcolemma; sarcoplasm; synaptic vesicle membrane,PF04440;,,,,,,,,,DTBP1_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; blood coagulation [GO:0007596]; melanosome organization [GO:0032438]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; platelet dense granule organization [GO:0060155]; positive regulation of gene expression [GO:0010628]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of dopamine secretion [GO:0014059]; regulation of JUN kinase activity [GO:0043506] comp133410_c0_seq1,868,32.8341,0.49828048,616,4434,,9.00E-26,Q5D016,Prefoldin subunit 1,Prefoldin subunit 1,GO:0016272; GO:0006457,prefoldin complex; protein folding,PF01920;,1.00E-13,CHOYP_LOC100694901.3.3,6.00E-73,ruditapes2_c693,,,,,PFD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein folding [GO:0006457] comp133411_c0_seq1,264,39.7727,0.1974693,16,110,,2.00E-43,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp133412_c0_seq1,2046,29.8631,0.46210666,886,4039,,,,,,,,,,,8.00E-19,ruditapes_c12172,,,,,,, comp133414_c0_seq1,1477,38.2532,0.51974303,3,0,,3.00E-25,Q6PCJ1,Dynactin subunit 1,Dynactin subunit 1,GO:0005737; GO:0005869; GO:0030286; GO:0005874; GO:0010970; GO:0003774,cytoplasm; dynactin complex; dynein complex; microtubule; microtubule-based transport; motor activity,PF01302;PF12455;,4.00E-23,CHOYP_DCTN1.2.2,,,,,,,DCTN1_XENLA,Xenopus laevis (African clawed frog),cytoplasmic microtubule organization [GO:0031122]; establishment of localization by movement along microtubule [GO:0010970]; positive regulation of intracellular protein transport [GO:0090316] comp133414_c0_seq2,421,47.981,0.29244794,14,60,,2.00E-12,Q8N3C7,CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),,,PF12796;PF01302;,,,,,,,,,CLIP4_HUMAN,Homo sapiens (Human), comp133414_c0_seq4,2006,41.5254,0.4587833,60,111,,,,,,,,,1.00E-87,CHOYP_DCTN1.2.2,,,,,,,,, comp133414_c0_seq6,1335,44.4944,0.4129685,0,0,,2.00E-155,P35458,Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p150-glued),Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p150-glued),GO:0005737; GO:0005869; GO:0030286; GO:0005874; GO:0010970; GO:0003774,cytoplasm; dynactin complex; dynein complex; microtubule; microtubule-based transport; motor activity,PF01302;PF12455;,,,,,,,,,DCTN1_CHICK,Gallus gallus (Chicken),cytoplasmic microtubule organization [GO:0031122]; establishment of localization by movement along microtubule [GO:0010970]; positive regulation of intracellular protein transport [GO:0090316] comp133419_c0_seq2,2305,43.1236,0.52055254,105,322,,0,Q92503,SEC14-like protein 1,SEC14-like protein 1,GO:0005794; GO:0016021; GO:0016020; GO:0006810,Golgi apparatus; integral to membrane; membrane; transport,PF00650;PF03765;PF04707;,0,CHOYP_S14L1.1.1,,,,,,,S14L1_HUMAN,Homo sapiens (Human),choline transport [GO:0015871]; innate immune response [GO:0045087]; negative regulation of RIG-I signaling pathway [GO:0039536] comp133421_c0_seq1,1186,34.6543,0.87699667,5701,73,,,,,,,,,2.00E-13,CHOYP_LOC577313.4.5,2.00E-43,ruditapes2_c1310,,,,,,, comp133422_c0_seq1,1251,37.8897,0.33811054,306,2399,,2.00E-120,Q9D7J9,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial","Enoyl-CoA hydratase domain-containing protein 3, mitochondrial",GO:0003824; GO:0005739,catalytic activity; mitochondrion,PF00378;,5.00E-85,CHOYP_LOC100695307.1.1,,,,,,,ECHD3_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp133423_c0_seq1,1345,43.7175,0.6505025,59,141,,7.00E-19,Q4J9D2,Uncharacterized protein Saci_1252,Uncharacterized protein Saci_1252,,,PF01661;,,,,,,,,,Y1252_SULAC,Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770), comp133426_c0_seq3,1126,32.5933,0.30263182,87,981,,4.00E-34,P56395,Cytochrome b5,Cytochrome b5,GO:0005789; GO:0006631; GO:0020037; GO:0016021; GO:0016020; GO:0046872; GO:0005739; GO:0004768,endoplasmic reticulum membrane; fatty acid metabolic process; heme binding; integral to membrane; membrane; metal ion binding; mitochondrion; stearoyl-CoA 9-desaturase activity,PF00173;,4.00E-34,CHOYP_CYB5.2.2,2.00E-81,ruditapes_c3894,,,,,CYB5_MOUSE,Mus musculus (Mouse),fatty acid metabolic process [GO:0006631]; response to cadmium ion [GO:0046686] comp133431_c0_seq1,1309,34.4538,0.46972139,60,216,,3.00E-39,Q5M7E0,Protein FAM210A,Protein FAM210A,GO:0016021; GO:0005739,integral to membrane; mitochondrion,PF06916;,3.00E-11,CHOYP_LOC655522.1.1,,,,,,,F210A_XENLA,Xenopus laevis (African clawed frog), comp133432_c0_seq2,971,43.4604,1.00539772,5,349,,6.00E-59,P08635,"S-acyl fatty acid synthase thioesterase, medium chain (EC 3.1.2.14) (Oleoyl-ACP hydrolase) (Thioesterase II) (Thioesterase domain-containing protein 1)","S-acyl fatty acid synthase thioesterase, medium chain (EC 3.1.2.14) (Oleoyl-ACP hydrolase) (Thioesterase II) (Thioesterase domain-containing protein 1)",GO:0006633; GO:0016295; GO:0004320; GO:0016296,fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity,PF00975;,,,,,,,,,SAST_RAT,Rattus norvegicus (Rat),fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338] comp133436_c0_seq4,574,45.8188,0.49896021,0,0,,,,,,,,,,,2.00E-21,ruditapes_c938,,,,,,, comp133440_c0_seq2,1204,38.1229,1.04451665,43,298,,1.00E-17,Q20681,BTB and MATH domain-containing protein 38,BTB and MATH domain-containing protein 38,,,PF00651;PF00917;,,,,,,,,,BAT38_CAEEL,Caenorhabditis elegans, comp133442_c0_seq2,1187,40.9436,0.450932,7,154,,3.00E-73,Q9D0K0,TBC1 domain family member 7,TBC1 domain family member 7,GO:0005097; GO:0032862; GO:0016023; GO:0031410; GO:0032007; GO:0032851; GO:0031398; GO:0070848,Rab GTPase activator activity; activation of Rho GTPase activity; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; negative regulation of TOR signaling cascade; positive regulation of Rab GTPase activity; positive regulation of protein ubiquitination; response to growth factor stimulus,PF00566;,,,,,,,,,TBCD7_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; negative regulation of cilium assembly [GO:1902018]; negative regulation of TOR signaling [GO:0032007]; positive regulation of protein ubiquitination [GO:0031398]; response to growth factor [GO:0070848] comp133443_c0_seq1,1639,45.8816,0.47709955,2,0,,,,,,,,,2.00E-16,CHOYP_BEGAIN.1.1,,,,,,,,, comp133443_c0_seq2,1201,51.9567,0.40763378,0,0,,2.00E-09,Q04164,Putative epidermal cell surface receptor (Stranded at second protein),Putative epidermal cell surface receptor (Stranded at second protein),GO:0016324; GO:0002168; GO:0005887; GO:0004872,apical plasma membrane; instar larval development; integral to plasma membrane; receptor activity,PF00041;,2.00E-14,CHOYP_MATN1.2.5,1.00E-58,ruditapes_c16063,,,,,SAS_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; instar larval development [GO:0002168] comp133443_c0_seq3,1173,43.2225,0.5877351,7,26,,,,,,,,,,,3.00E-59,ruditapes_c93,,,,,,, comp133443_c0_seq4,2734,48.5735,0.45333694,4,14,,2.00E-08,Q04164,Putative epidermal cell surface receptor (Stranded at second protein),Putative epidermal cell surface receptor (Stranded at second protein),GO:0016324; GO:0002168; GO:0005887; GO:0004872,apical plasma membrane; instar larval development; integral to plasma membrane; receptor activity,PF00041;,,,,,,,,,SAS_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; instar larval development [GO:0002168] comp133443_c0_seq5,1028,52.2374,0.38560758,0,0,,,,,,,,,1.00E-14,CHOYP_MATN1.2.5,,,,,,,,, comp133452_c0_seq1,820,43.2927,1.12201413,506,3403,,2.00E-12,Q57951,Universal stress protein MJ0531 (USP MJ0531),Universal stress protein MJ0531 (USP MJ0531),GO:0006950,response to stress,PF00582;,1.00E-13,CHOYP_LOC587133.1.1,5.00E-74,ruditapes2_c1446,,,,,Y531_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),response to stress [GO:0006950] comp133453_c1_seq1,2363,43.2078,0.54434937,144,195,,6.00E-23,Q3B7D3,Tectonic-2,Tectonic-2,GO:0036038; GO:0042384; GO:0005737; GO:0016021; GO:0005932; GO:0007224,TCTN-B9D complex; cilium assembly; cytoplasm; integral to membrane; microtubule basal body; smoothened signaling pathway,PF07773;,,,,,,,,,TECT2_RAT,Rattus norvegicus (Rat),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; smoothened signaling pathway [GO:0007224] comp133455_c0_seq1,831,35.8604,0.43487827,70,724,,5.00E-07,Q9NRH1,Yae1 domain-containing protein 1,Yae1 domain-containing protein 1,,,PF09811;,,,,,,,,,YAED1_HUMAN,Homo sapiens (Human), comp133457_c0_seq1,688,38.9535,0.74401976,18,65,,3.00E-15,P80197,Actin-fragmin kinase (AFK) (EC 2.7.11.1),Actin-fragmin kinase (AFK) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0004674,ATP binding; cytoplasm; protein serine/threonine kinase activity,PF09192;,3.00E-33,CHOYP_KLDC3.1.1,,,,,,,AFK_PHYPO,Physarum polycephalum (Slime mold), comp133457_c0_seq2,914,41.2473,0.44037763,56,180,,2.00E-70,Q8VEM9,Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein),Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein),GO:0003682; GO:0005737; GO:0007126; GO:0000790,chromatin binding; cytoplasm; meiosis; nuclear chromatin,PF07646;,,,,,,,,,KLDC3_MOUSE,Mus musculus (Mouse),meiotic cell cycle [GO:0051321] comp133460_c0_seq1,1557,37.3154,0.57749265,227,815,,6.00E-26,Q71RG4,Transmembrane and ubiquitin-like domain-containing protein 2,Transmembrane and ubiquitin-like domain-containing protein 2,GO:0016021,integral to membrane,PF00240;,1.00E-18,CHOYP_PHUM_PHUM306700.1.1,,,,,,,TMUB2_HUMAN,Homo sapiens (Human), comp133463_c0_seq1,1508,29.9072,0.35968552,220,1690,,,,,,,,,,,5.00E-14,ruditapes_c1417,,,,,,, comp133466_c0_seq1,1956,37.6278,0.376728,203,1097,,1.00E-177,Q66PG1,Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B),"Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B) [Includes: Xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)]",GO:0005794; GO:0000139; GO:0016021; GO:0006486; GO:0016757,"Golgi apparatus; Golgi membrane; integral to membrane; protein glycosylation; transferase activity, transferring glycosyl groups",PF01501;,2.00E-105,CHOYP_LARGE.1.2,,,,,,,LARG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] comp133466_c0_seq2,947,36.8532,0.59508458,285,1171,,2.00E-150,Q66PG2,Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A),"Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A) [Includes: Xylosyltransferase LARGE (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE (EC 2.4.1.-)]",GO:0000139; GO:0016021; GO:0016757,"Golgi membrane; integral to membrane; transferase activity, transferring glycosyl groups",PF01501;,,,,,,,,,LARGE_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein O-linked mannosylation [GO:0035269]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue regeneration [GO:0043403] comp133473_c1_seq1,3763,37.7358,0.46178386,107,142,,0,Q9VN03,"ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC 3.6.4.13)","ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC 3.6.4.13)",GO:0005524; GO:0003677; GO:0003678; GO:0005759; GO:0005634,ATP binding; DNA binding; DNA helicase activity; mitochondrial matrix; nucleus,PF00271;PF12513;,3.00E-11,CHOYP_SUV3.1.1,,,,,,,SUV3_DROME,Drosophila melanogaster (Fruit fly),DNA duplex unwinding [GO:0032508]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA processing [GO:0000963]; mitochondrial tRNA processing [GO:0090646]; oxidative phosphorylation [GO:0006119]; positive regulation of mitochondrial translation [GO:0070131]; regulation of mitochondrial mRNA stability [GO:0044528]; respiratory electron transport chain [GO:0022904] comp133473_c1_seq2,2292,34.8604,0.43667881,0,22,,6.00E-44,A4IG62,"ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1)","ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1)",GO:0034458; GO:0005524; GO:0004004; GO:0003677; GO:0003678; GO:0006310; GO:0070827; GO:0003725; GO:0000965; GO:0045025; GO:0000958; GO:0035946; GO:0005759; GO:0035945; GO:0042645; GO:0070584; GO:0043066; GO:0005634; GO:0030307; GO:0000962,3'-5' RNA helicase activity; ATP binding; ATP-dependent RNA helicase activity; DNA binding; DNA helicase activity; DNA recombination; chromatin maintenance; double-stranded RNA binding; mitochondrial RNA 3'-end processing; mitochondrial degradosome; mitochondrial mRNA catabolic process; mitochondrial mRNA surveillance; mitochondrial matrix; mitochondrial ncRNA surveillance; mitochondrial nucleoid; mitochondrion morphogenesis; negative regulation of apoptotic process; nucleus; positive regulation of cell growth; positive regulation of mitochondrial RNA catabolic process,PF00271;PF12513;,,,,,,,,,SUV3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chromatin maintenance [GO:0070827]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; liver development [GO:0001889]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA surveillance [GO:0035946]; mitochondrial ncRNA surveillance [GO:0035945]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA surveillance [GO:2000827]; mitochondrion morphogenesis [GO:0070584]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; RNA catabolic process [GO:0006401] comp133473_c1_seq3,539,38.59,0.50000172,0,4,,2.00E-43,Q295E6,"ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC 3.6.4.13)","ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC 3.6.4.13)",GO:0005524; GO:0003677; GO:0003678; GO:0005759; GO:0005634,ATP binding; DNA binding; DNA helicase activity; mitochondrial matrix; nucleus,PF00271;,,,,,,,,,SUV3_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),DNA duplex unwinding [GO:0032508] comp133480_c1_seq1,491,41.9552,0.82258406,7,69,,,,,,,,,1.00E-17,CHOYP_DHRS1.1.1,,,,,,,,, comp133480_c2_seq1,275,40.7273,1.07290048,3,17,,2.00E-34,Q96LJ7,Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 19C member 1),GO:0005783; GO:0005743; GO:0016491,endoplasmic reticulum; mitochondrial inner membrane; oxidoreductase activity,PF00106;,9.00E-29,CHOYP_BRAFLDRAFT_205095.1.2,,,,,,,DHRS1_HUMAN,Homo sapiens (Human), comp133481_c0_seq1,1259,45.3535,0.76100134,0,0,,,,,,,,,5.00E-135,CHOYP_DOCK9.2.2,,,,,,,,, comp133481_c0_seq3,1208,45.3642,0.74557644,0,0,,1.00E-164,Q5JSL3,Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2),Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2),GO:0005089; GO:0007596; GO:0005829; GO:0005543; GO:0007264,Rho guanyl-nucleotide exchange factor activity; blood coagulation; cytosol; phospholipid binding; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;PF00169;,5.00E-148,CHOYP_DOCK9.1.2,,,,,,,DOC11_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; small GTPase mediated signal transduction [GO:0007264] comp133481_c0_seq4,820,44.5122,0.61729415,0,0,,,,,,,,,2.00E-43,CHOYP_DOC11.1.1,,,,,,,,, comp133494_c1_seq1,805,41.3665,1.02025474,46,175,,1.00E-14,Q9D6P8,Calmodulin-like protein 3,Calmodulin-like protein 3,GO:0005509,calcium ion binding,PF13499;,,,1.00E-30,ruditapes_c12967,,,,,CALL3_MOUSE,Mus musculus (Mouse), comp133495_c0_seq1,2681,41.1041,0.70176878,37,10,,7.00E-18,P17010,Zinc finger X-chromosomal protein,Zinc finger X-chromosomal protein,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0003713; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent",PF00096;PF04704;,,,,,,,,,ZFX_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133495_c0_seq3,1734,40.9458,0.66557465,0,0,,5.00E-36,Q5JVG2,Zinc finger protein 484,Zinc finger protein 484,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN484_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133495_c0_seq4,2018,40.9316,0.63189145,0,0,,3.00E-30,P0CG31,Putative zinc finger protein 286B,Putative zinc finger protein 286B,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13465;,,,,,,,,,Z286B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133497_c1_seq1,1087,42.5943,0.44982373,28,200,,4.00E-82,Q9Z1N0,Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),GO:0003995; GO:0003997; GO:0033540; GO:0019395; GO:0050660; GO:0006091; GO:0005777; GO:0006693,acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid oxidation; flavin adenine dinucleotide binding; generation of precursor metabolites and energy; peroxisome; prostaglandin metabolic process,PF01756;PF02770;PF14749;,2.00E-20,CHOYP_ACOX1.1.3,,,,,,,ACOX1_CAVPO,Cavia porcellus (Guinea pig),fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693] comp133500_c0_seq1,1461,40.3833,0.5216563,137,575,,6.00E-82,Q66KI9,5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4),5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4),GO:0003723; GO:0008168; GO:0005739; GO:0006364,RNA binding; methyltransferase activity; mitochondrion; rRNA processing,PF01189;,2.00E-34,CHOYP_NSUN4.1.1,,,,,,,NSUN4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),rRNA methylation [GO:0031167] comp133504_c1_seq1,893,44.1209,0.54156199,59,22,,3.00E-39,O95239,Chromosome-associated kinesin KIF4A (Chromokinesin-A),Chromosome-associated kinesin KIF4A (Chromokinesin-A),GO:0005524; GO:0003677; GO:0008089; GO:0019886; GO:0007411; GO:0007596; GO:0005694; GO:0005829; GO:0005871; GO:0003777; GO:0030496; GO:0016363; GO:0005634; GO:0006996; GO:0005876,ATP binding; DNA binding; anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; blood coagulation; chromosome; cytosol; kinesin complex; microtubule motor activity; midbody; nuclear matrix; nucleus; organelle organization; spindle microtubule,PF00225;,6.00E-19,CHOYP_LOC100378372.1.1,,,,,,,KIF4A_HUMAN,Homo sapiens (Human),"anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp133504_c1_seq3,841,45.541,0.61466843,27,17,,1.00E-100,Q91WD7,Kinesin-like protein KIF18A,Kinesin-like protein KIF18A,GO:0005524; GO:0003779; GO:0005901; GO:0005737; GO:0005871; GO:0005828; GO:0007019; GO:0005815; GO:0051010; GO:0007018; GO:0007080; GO:0005634; GO:0008574; GO:0015031; GO:0001726; GO:0070463; GO:0043130,ATP binding; actin binding; caveola; cytoplasm; kinesin complex; kinetochore microtubule; microtubule depolymerization; microtubule organizing center; microtubule plus-end binding; microtubule-based movement; mitotic metaphase plate congression; nucleus; plus-end-directed microtubule motor activity; protein transport; ruffle; tubulin-dependent ATPase activity; ubiquitin binding,PF00225;,,,,,,,,,KI18A_MOUSE,Mus musculus (Mouse),male meiosis [GO:0007140]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019]; mitotic metaphase plate congression [GO:0007080]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; seminiferous tubule development [GO:0072520] comp133506_c0_seq1,1174,37.6491,0.92029665,653,5,male>female,2.00E-10,Q2KIR0,Uncharacterized protein C4orf45 homolog,Uncharacterized protein C4orf45 homolog,,,PF15123;,1.00E-29,CHOYP_NEMVEDRAFT_V1G208725.1.1,,,,,,,CD045_BOVIN,Bos taurus (Bovine), comp133507_c0_seq1,682,43.5484,0.47757887,1,0,,1.00E-72,P23919,Thymidylate kinase (EC 2.7.4.9) (dTMP kinase),Thymidylate kinase (EC 2.7.4.9) (dTMP kinase),GO:0005524; GO:0007049; GO:0008283; GO:0071363; GO:0005829; GO:0006233; GO:0006235; GO:0005758; GO:0005759; GO:0045445; GO:0015949; GO:0050145; GO:0046686; GO:0043627; GO:0004798,ATP binding; cell cycle; cell proliferation; cellular response to growth factor stimulus; cytosol; dTDP biosynthetic process; dTTP biosynthetic process; mitochondrial intermembrane space; mitochondrial matrix; myoblast differentiation; nucleobase-containing small molecule interconversion; nucleoside phosphate kinase activity; response to cadmium ion; response to estrogen stimulus; thymidylate kinase activity,,,,,,,,,,KTHY_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell proliferation [GO:0008283]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627] comp133507_c0_seq2,592,43.75,0.46636552,0,0,,2.00E-09,P0C8G0,Truncated thymidylate kinase,Truncated thymidylate kinase,,,,2.00E-17,CHOYP_LOC100369259.1.1,,,,,,,KTHY_ASFM2,African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV), comp133508_c0_seq1,1299,33.7952,0.65124861,302,2026,,3.00E-40,D4ACN8,Plasminogen receptor (KT) (Plg-R(KT)),Plasminogen receptor (KT) (Plg-R(KT)),GO:0006935; GO:0006954; GO:0016021; GO:0005886,chemotaxis; inflammatory response; integral to membrane; plasma membrane,PF10166;,2.00E-25,CHOYP_BRAFLDRAFT_88556.1.1,,,,,,,PLRKT_RAT,Rattus norvegicus (Rat),chemotaxis [GO:0006935]; inflammatory response [GO:0006954]; positive regulation of plasminogen activation [GO:0010756] comp133515_c0_seq1,1160,37.7586,0.39090938,5,80,,4.00E-19,Q9UKC9,F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3),F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3),GO:0005737; GO:0016020; GO:0019048; GO:0006513; GO:0006508; GO:0006511; GO:0004842,cytoplasm; membrane; modulation by virus of host morphology or physiology; protein monoubiquitination; proteolysis; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12937;PF13516;,,,,,,,,,FBXL2_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; viral process [GO:0016032] comp133515_c0_seq2,894,38.7025,0.36421641,4,0,,6.00E-09,Q9QZH7,F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),GO:0005737,cytoplasm,PF12937;PF13516;,,,,,,,,,FXL20_RAT,Rattus norvegicus (Rat), comp133518_c1_seq2,972,47.7366,0.5314442,32,132,,5.00E-68,Q5JTW2,Centrosomal protein of 78 kDa (Cep78),Centrosomal protein of 78 kDa (Cep78),GO:0000086; GO:0005813; GO:0005829,G2/M transition of mitotic cell cycle; centrosome; cytosol,PF13516;,5.00E-109,CHOYP_LOC100368803.1.1,,,,,,,CEP78_HUMAN,Homo sapiens (Human),G2/M transition of mitotic cell cycle [GO:0000086] comp133522_c0_seq4,1655,45.5589,0.51283803,0,0,,5.00E-65,Q1E6R9,Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6),Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6),GO:0000139; GO:0017119; GO:0006891; GO:0015031,Golgi membrane; Golgi transport complex; intra-Golgi vesicle-mediated transport; protein transport,,0,CHOYP_COG6.1.1,,,,,,,COG6_COCIM,Coccidioides immitis (strain RS) (Valley fever fungus),intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp133522_c0_seq5,1968,44.4614,0.50441265,0,0,,0,Q3SZI7,Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6),Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6),GO:0000139; GO:0017119; GO:0070085; GO:0006891; GO:0015031,Golgi membrane; Golgi transport complex; glycosylation; intra-Golgi vesicle-mediated transport; protein transport,,,,,,,,,,COG6_BOVIN,Bos taurus (Bovine),glycosylation [GO:0070085]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp133522_c0_seq8,1505,45.1163,0.51016283,0,0,,0,Q3SZI7,Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6),Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6),GO:0000139; GO:0017119; GO:0070085; GO:0006891; GO:0015031,Golgi membrane; Golgi transport complex; glycosylation; intra-Golgi vesicle-mediated transport; protein transport,,0,CHOYP_COG6.1.1,,,,,,,COG6_BOVIN,Bos taurus (Bovine),glycosylation [GO:0070085]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp133525_c0_seq1,1953,38.9657,0.74349996,4836,10955,,4.00E-116,P85834,"Elongation factor Tu, mitochondrial","Elongation factor Tu, mitochondrial",GO:0005525; GO:0006184; GO:0003924; GO:0042645; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; mitochondrial nucleoid; translation elongation factor activity,PF03144;PF03143;,8.00E-78,CHOYP_LOC658895.1.1,,,,,,,EFTU_RAT,Rattus norvegicus (Rat),mitochondrial translational elongation [GO:0070125]; response to ethanol [GO:0045471] comp133528_c0_seq1,1747,37.5501,0.53859962,311,101,,4.00E-72,Q6GQN0,Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein),Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein),GO:0005814; GO:0035083; GO:0036064; GO:0072372; GO:0018095; GO:0015031; GO:0070740,centriole; cilium axoneme assembly; cilium basal body; primary cilium; protein polyglutamylation; protein transport; tubulin-glutamic acid ligase activity,PF00581;,1.00E-44,CHOYP_MEST.2.2,,,,,,,CEP41_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; protein polyglutamylation [GO:0018095]; protein transport [GO:0015031]; single organismal cell-cell adhesion [GO:0016337] comp133529_c0_seq1,691,36.0347,1.04060368,94,241,,,,,,,,,,,7.00E-33,ruditapes2_c813,,,,,,, comp133531_c0_seq1,2149,37.2266,0.43331768,2792,14832,,0,Q7ZU42,Obg-like ATPase 1,Obg-like ATPase 1,GO:0005524; GO:0005525; GO:0005737; GO:0016787; GO:0005730,ATP binding; GTP binding; cytoplasm; hydrolase activity; nucleolus,PF01926;PF06071;,0,CHOYP_OLA1.2.2,,,,,,,OLA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp133538_c1_seq1,2040,48.4804,0.52950887,27,18,,,,,,,,,0,CHOYP_LOC100370269.1.1,,,,,,,,, comp133538_c1_seq2,2259,47.189,0.5158935,18,8,,0,A1L1C7,PAB-dependent poly(A)-specific ribonuclease subunit 3,PAB-dependent poly(A)-specific ribonuclease subunit PAN3 (PAB1P-dependent poly(A)-nuclease) (PAN deadenylation complex subunit 3),GO:0005524; GO:0031251; GO:0006397; GO:0046872; GO:0004672,ATP binding; PAN complex; mRNA processing; metal ion binding; protein kinase activity,PF00642;,0,CHOYP_LOC100370269.1.1,,,,,,,PAN3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606] comp133539_c0_seq2,1316,38.6018,0.58200791,57,161,,3.00E-06,Q32KT5,Uncharacterized protein C6orf136 homolog,Uncharacterized protein C6orf136 homolog,,,PF10184;,,,,,,,,,CF136_BOVIN,Bos taurus (Bovine), comp133544_c0_seq5,1765,35.9773,0.61317031,0,0,,,,,,,,,,,4.00E-15,ruditapes_c14944,,,,,,, comp133546_c0_seq1,1967,40.3152,0.38844753,55,324,,6.00E-116,Q9NYV6,RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA),RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA),GO:0008283; GO:0007028; GO:0048872; GO:0001701; GO:0043066; GO:0005730; GO:0007000; GO:0005654; GO:0045893; GO:2000142; GO:0042254; GO:0006361,"cell proliferation; cytoplasm organization; homeostasis of number of cells; in utero embryonic development; negative regulation of apoptotic process; nucleolus; nucleolus organization; nucleoplasm; positive regulation of transcription, DNA-dependent; regulation of DNA-dependent transcription, initiation; ribosome biogenesis; transcription initiation from RNA polymerase I promoter",PF05327;,,,,,,,,,RRN3_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; cytoplasm organization [GO:0007028]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; nucleolus organization [GO:0007000]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of DNA-templated transcription, initiation [GO:2000142]; ribosome biogenesis [GO:0042254]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp133548_c1_seq1,1299,41.8784,0.4775552,43,149,,2.00E-23,P22105,Tenascin-X (TN-X) (Hexabrachion-like protein),Tenascin-X (TN-X) (Hexabrachion-like protein),GO:0030036; GO:0007155; GO:0016337; GO:0007160; GO:0030199; GO:0032963; GO:0048251; GO:0043206; GO:0005615; GO:0006631; GO:0008201; GO:0005178; GO:0005622; GO:0005578; GO:0043506; GO:0006641,actin cytoskeleton organization; cell adhesion; cell-cell adhesion; cell-matrix adhesion; collagen fibril organization; collagen metabolic process; elastic fiber assembly; extracellular fibril organization; extracellular space; fatty acid metabolic process; heparin binding; integrin binding; intracellular; proteinaceous extracellular matrix; regulation of JUN kinase activity; triglyceride metabolic process,PF07974;PF00147;PF00041;PF12661;,,,,,,,,,TENX_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; fatty acid metabolic process [GO:0006631]; regulation of JUN kinase activity [GO:0043506]; single organismal cell-cell adhesion [GO:0016337]; triglyceride metabolic process [GO:0006641] comp133548_c1_seq3,590,43.2203,0.36450086,0,0,,1.00E-06,P29461,Tyrosine-protein phosphatase 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2) (PTPase 2),Tyrosine-protein phosphatase 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2) (PTPase 2),GO:0005737; GO:0000200; GO:0000173; GO:0005634; GO:0004725; GO:0032880; GO:0043937,cytoplasm; inactivation of MAPK activity involved in cell wall biogenesis; inactivation of MAPK activity involved in osmosensory signaling pathway; nucleus; protein tyrosine phosphatase activity; regulation of protein localization; regulation of sporulation,PF00102;,4.00E-18,CHOYP_LOC100208023.7.8,,,,,,,PTP2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),inactivation of MAPK activity involved in cell wall organization or biogenesis [GO:0000200]; inactivation of MAPK activity involved in osmosensory signaling pathway [GO:0000173]; protein dephosphorylation [GO:0006470]; regulation of protein localization [GO:0032880]; regulation of sporulation [GO:0043937] comp133548_c1_seq4,1470,42.9932,0.47461204,39,135,,1.00E-71,P18433,Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),GO:0007411; GO:0008286; GO:0005887; GO:0006468; GO:0005001,axon guidance; insulin receptor signaling pathway; integral to plasma membrane; protein phosphorylation; transmembrane receptor protein tyrosine phosphatase activity,PF00102;,2.00E-13,CHOYP_LOC101076860.1.1,,,,,,,PTPRA_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165] comp133548_c2_seq1,1224,41.0948,0.39745587,31,132,,3.00E-17,Q9W7R4,Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3),Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3),GO:0030424; GO:0007156; GO:0016021; GO:0016020; GO:0010976; GO:0046982; GO:0042803; GO:0007165,axon; homophilic cell adhesion; integral to membrane; membrane; positive regulation of neuron projection development; protein heterodimerization activity; protein homodimerization activity; signal transduction,PF12661;PF06484;PF15636;,,,,,,,,,TEN3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),dendrite guidance [GO:0070983]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of neuron projection development [GO:0010976]; retinal ganglion cell axon guidance [GO:0031290]; self proteolysis [GO:0097264]; signal transduction [GO:0007165] comp133549_c1_seq4,2002,41.1588,0.51920858,50,9,,6.00E-43,Q6P1L5,Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein),Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein),,,PF15388;,,,,,,,,,F117B_HUMAN,Homo sapiens (Human), comp133552_c0_seq1,3442,42.1557,0.28976495,4032,15852,,0,Q5F418,26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1),26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1),GO:0030234; GO:0022624; GO:0050790; GO:0042176,enzyme regulator activity; proteasome accessory complex; regulation of catalytic activity; regulation of protein catabolic process,PF01851;,0,CHOYP_PSMD1.1.1,0,ruditapes2_c427,,,,,PSMD1_CHICK,Gallus gallus (Chicken),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] comp133553_c0_seq1,766,38.9034,0.27649651,16,48,,1.00E-25,Q5UR67,Uncharacterized protein R617,N-glycosidase R617 (EC 3.2.2.-) (Riboflavin biosynthesis intermediates N-glycosidase),,,PF08719;,,,,,,,,,YR617_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),metabolic process [GO:0008152] comp133555_c1_seq1,1927,31.7592,0.57119046,16,4,,2.00E-37,P47194,Synaptobrevin,Synaptobrevin,GO:0030054; GO:0016021; GO:0043005; GO:0030672; GO:0016192,cell junction; integral to membrane; neuron projection; synaptic vesicle membrane; vesicle-mediated transport,PF00957;,,,,,,,,,SYB_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),vesicle-mediated transport [GO:0016192] comp133555_c1_seq2,1894,31.0982,0.54092643,15,50,,2.00E-37,P47194,Synaptobrevin,Synaptobrevin,GO:0030054; GO:0016021; GO:0043005; GO:0030672; GO:0016192,cell junction; integral to membrane; neuron projection; synaptic vesicle membrane; vesicle-mediated transport,PF00957;,5.00E-42,CHOYP_SYB.2.3,,,,,,,SYB_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),vesicle-mediated transport [GO:0016192] comp133560_c0_seq1,1935,42.0155,0.34427284,0,0,,6.00E-151,O95831,"Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)","Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)",GO:0003677; GO:0006919; GO:0006309; GO:0045454; GO:0005829; GO:0009055; GO:0050660; GO:0070059; GO:0005743; GO:0005758; GO:0032981; GO:0051402; GO:0030182; GO:0005634; GO:0016651; GO:0048471,"DNA binding; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic DNA fragmentation; cell redox homeostasis; cytosol; electron carrier activity; flavin adenine dinucleotide binding; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex I assembly; neuron apoptotic process; neuron differentiation; nucleus; oxidoreductase activity, acting on NAD(P)H; perinuclear region of cytoplasm",PF14721;PF07992;,,,,,,,,,AIFM1_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; DNA catabolic process [GO:0006308]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636] comp133560_c0_seq2,2275,39.7802,0.33875103,0,0,,2.00E-149,O95831,"Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)","Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)",GO:0003677; GO:0006919; GO:0006309; GO:0045454; GO:0005829; GO:0009055; GO:0050660; GO:0070059; GO:0005743; GO:0005758; GO:0032981; GO:0051402; GO:0030182; GO:0005634; GO:0016651; GO:0048471,"DNA binding; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic DNA fragmentation; cell redox homeostasis; cytosol; electron carrier activity; flavin adenine dinucleotide binding; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex I assembly; neuron apoptotic process; neuron differentiation; nucleus; oxidoreductase activity, acting on NAD(P)H; perinuclear region of cytoplasm",PF14721;PF07992;,,,,,,,,,AIFM1_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; DNA catabolic process [GO:0006308]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636] comp133563_c0_seq1,607,44.9753,0.45699684,151,807,,1.00E-37,Q5RBA1,Inhibitor of growth protein 3,Inhibitor of growth protein 3,GO:0032777; GO:0043968; GO:0043967; GO:0043065; GO:0040008; GO:0006355; GO:0006351; GO:0008270,"Piccolo NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; positive regulation of apoptotic process; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF12998;,3.00E-32,CHOYP_STK11.1.1,,,,,,,ING3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of apoptotic process [GO:0043065]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133563_c0_seq2,978,40.2863,0.30278382,122,640,,2.00E-63,Q498T3,Inhibitor of growth protein 3,Inhibitor of growth protein 3,GO:0032777; GO:0043968; GO:0043967; GO:0004402; GO:0043065; GO:0040008; GO:0006355; GO:0006351; GO:0008270,"Piccolo NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; histone acetyltransferase activity; positive regulation of apoptotic process; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF12998;,5.00E-83,CHOYP_ING3.1.1,,,,,,,ING3_RAT,Rattus norvegicus (Rat),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of apoptotic process [GO:0043065]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133568_c0_seq1,867,35.8708,0.25291409,0,0,,1.00E-44,Q6GPV5,E3 ubiquitin-protein ligase RNF181 (EC 6.3.2.-) (RING finger protein 181),E3 ubiquitin-protein ligase RNF181 (EC 6.3.2.-) (RING finger protein 181),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,PF13639;,,,,,,,,,RN181_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567] comp133568_c0_seq2,890,35.5056,0.25154297,0,0,,5.00E-23,Q9VE61,E3 ubiquitin-protein ligase RNF181 homolog (EC 6.3.2.-) (RING finger protein 181 homolog),E3 ubiquitin-protein ligase RNF181 homolog (EC 6.3.2.-) (RING finger protein 181 homolog),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,PF13639;,5.00E-77,CHOYP_BRAFLDRAFT_285971.1.1,,,,,,,RN181_DROME,Drosophila melanogaster (Fruit fly),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp133568_c0_seq4,883,35.4473,0.29090946,0,0,,,,,,,,,4.00E-77,CHOYP_BRAFLDRAFT_285971.1.1,,,,,,,,, comp133570_c0_seq1,2101,36.1733,0.41987525,34,67,,1.00E-49,Q5EA19,ADP-ribosylation factor-like protein 15,ADP-ribosylation factor-like protein 15,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00025;,2.00E-34,CHOYP_ARL15.1.1,2.00E-59,ruditapes_c17940,,,,,ARL15_BOVIN,Bos taurus (Bovine),small GTPase mediated signal transduction [GO:0007264] comp133573_c1_seq2,1857,40.9801,0.53104973,0,0,,4.00E-120,A6QR55,Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),GO:0005737; GO:0046872; GO:0031397; GO:0005634; GO:0016579; GO:0034394; GO:0031647; GO:0004221; GO:0006511; GO:0004843,cytoplasm; metal ion binding; negative regulation of protein ubiquitination; nucleus; protein deubiquitination; protein localization to cell surface; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;,6.00E-48,CHOYP_UBP15.4.4,7.00E-19,ruditapes_c31884,,,,,UBP4_BOVIN,Bos taurus (Bovine),negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511] comp133573_c1_seq4,2197,41.4201,0.51358901,47,6,,0,Q9Y4E8,Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4),Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4),GO:0030509; GO:0004197; GO:0005737; GO:0035520; GO:0030512; GO:0005634; GO:0060389; GO:0007179; GO:0004221; GO:0006511; GO:0004843,BMP signaling pathway; cysteine-type endopeptidase activity; cytoplasm; monoubiquitinated protein deubiquitination; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; pathway-restricted SMAD protein phosphorylation; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;PF14533;,,,1.00E-48,ruditapes_c26285,,,,,UBP15_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp133580_c0_seq1,2764,41.3531,0.58569366,3122,376,,3.00E-124,Q08BC4,Sperm-tail PG-rich repeat-containing protein 2,Sperm-tail PG-rich repeat-containing protein 2,,,PF07004;,3.00E-135,CHOYP_LOC100374155.1.1,,,,,,,STPG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp133587_c0_seq1,1485,44.9158,0.40147713,243,494,,4.00E-163,Q9UHL4,Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase),Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase),GO:0004177; GO:0016023; GO:0005829; GO:0008239; GO:0005576; GO:0005764; GO:0006508; GO:0008236,aminopeptidase activity; cytoplasmic membrane-bounded vesicle; cytosol; dipeptidyl-peptidase activity; extracellular region; lysosome; proteolysis; serine-type peptidase activity,PF05577;,3.00E-50,CHOYP_BRAFLDRAFT_128878.1.1,,,,,,,DPP2_HUMAN,Homo sapiens (Human), comp133589_c1_seq3,1480,45.2703,0.35785449,0,0,,5.00E-59,Q0WVW7,ATP-dependent DNA helicase Q-like 5 (EC 3.6.4.12) (RecQ-like protein 5) (AtRecQ5) (AtRecQl5),ATP-dependent DNA helicase Q-like 5 (EC 3.6.4.12) (RecQ-like protein 5) (AtRecQ5) (AtRecQl5),GO:0005524; GO:0008026; GO:0006310; GO:0042631; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; DNA recombination; cellular response to water deprivation; nucleic acid binding; nucleus,PF00270;PF00271;,,,,,,,,,RQL5_ARATH,Arabidopsis thaliana (Mouse-ear cress),base-excision repair [GO:0006284]; cellular response to water deprivation [GO:0042631]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302] comp133589_c1_seq4,2101,44.7882,0.43268053,49,75,,0,Q9DEY9,Bloom syndrome protein homolog (xBLM) (EC 3.6.4.12) (RecQ helicase homolog),Bloom syndrome protein homolog (xBLM) (EC 3.6.4.12) (RecQ helicase homolog),GO:0005524; GO:0043140; GO:0004003; GO:0003677; GO:0000729; GO:0006310; GO:0006260; GO:0005634,ATP binding; ATP-dependent 3'-5' DNA helicase activity; ATP-dependent DNA helicase activity; DNA binding; DNA double-strand break processing; DNA recombination; DNA replication; nucleus,PF08072;PF16202;PF00270;PF00271;PF00570;PF16124;PF09382;,0,CHOYP_BLM.1.1,,,,,,,BLM_XENLA,Xenopus laevis (African clawed frog),DNA double-strand break processing [GO:0000729]; DNA recombination [GO:0006310]; DNA replication [GO:0006260] comp133590_c0_seq1,1363,37.2707,0.44648142,18,727,,1.00E-27,Q7Z9I4,Uncharacterized oxidoreductase C663.06c (EC 1.-.-.-),Uncharacterized oxidoreductase C663.06c (EC 1.-.-.-),GO:0005829; GO:0005634; GO:0016491,cytosol; nucleus; oxidoreductase activity,PF00106;,2.00E-39,CHOYP_LOC101175020.1.1,,,,,,,YCP6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp133592_c0_seq1,1053,41.9753,0.5122997,182,1969,,3.00E-111,Q9JLZ3,"Methylglutaconyl-CoA hydratase, mitochondrial (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH)","Methylglutaconyl-CoA hydratase, mitochondrial (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH)",GO:0004300; GO:0006552; GO:0003730; GO:0004490; GO:0005739; GO:0000288,"enoyl-CoA hydratase activity; leucine catabolic process; mRNA 3'-UTR binding; methylglutaconyl-CoA hydratase activity; mitochondrion; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",PF00378;,1.00E-52,CHOYP_AUHM.1.2,,,,,,,AUHM_MOUSE,Mus musculus (Mouse),"fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]" comp133595_c0_seq1,1635,43.1804,0.82074716,1208,5154,,,,,,,,,2.00E-46,CHOYP_LOC100640001.1.2,3.00E-55,ruditapes_c21770,,,,,,, comp133616_c0_seq2,839,41.5971,0.36261653,66,331,,1.00E-70,P85107,Trimethylguanosine synthase (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT),Trimethylguanosine synthase (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT),GO:0009452; GO:0071164; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"7-methylguanosine RNA capping; RNA trimethylguanosine synthase activity; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09445;,2.00E-69,CHOYP_TGS1.1.2,,,,,,,TGS1_RAT,Rattus norvegicus (Rat),"7-methylguanosine RNA capping [GO:0009452]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133618_c0_seq1,865,41.1561,0.27555083,87,444,,4.00E-78,Q812D3,Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3),Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3),GO:0008380; GO:0006397; GO:0003755; GO:0006457; GO:0000413; GO:0005681,RNA splicing; mRNA processing; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; spliceosomal complex,PF00160;,9.00E-67,CHOYP_LOC100929997.1.1,,,,,,,PPIL3_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397]; protein folding [GO:0006457]; RNA splicing [GO:0008380] comp133620_c1_seq2,1880,39.5745,0.71028573,43,368,,3.00E-150,Q5E9X2,Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6),Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6),GO:0005524; GO:0006915; GO:0005737; GO:0005856; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:0006355; GO:0006950; GO:0006351,"ATP binding; apoptotic process; cytoplasm; cytoskeleton; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of transcription, DNA-dependent; response to stress; transcription, DNA-dependent",PF00069;,1.00E-88,CHOYP_MP2K6.1.1,4.00E-28,ruditapes_c12960,,,,,MP2K6_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; cardiac muscle contraction [GO:0060048]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133621_c0_seq1,2144,39.9254,0.6437326,97,790,,3.00E-92,Q86VD1,MORC family CW-type zinc finger protein 1 (Cancer/testis antigen 33) (CT33),MORC family CW-type zinc finger protein 1 (Cancer/testis antigen 33) (CT33),GO:0005524; GO:0030154; GO:0007275; GO:0005634; GO:0007283; GO:0008270,ATP binding; cell differentiation; multicellular organismal development; nucleus; spermatogenesis; zinc ion binding,PF07496;,0,CHOYP_MORC2.1.1,6.00E-103,ruditapes_c11967,,,,,MORC1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp133621_c0_seq2,1546,39.9094,0.72093743,3,7,,3.00E-123,Q9Y6X9,MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1),MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1),GO:0005524; GO:0005829; GO:0005634; GO:0008270,ATP binding; cytosol; nucleus; zinc ion binding,PF07496;,,,,,,,,,MORC2_HUMAN,Homo sapiens (Human),fatty acid metabolic process [GO:0006631] comp133623_c0_seq1,1931,46.1419,0.88592616,1024,1850,,2.00E-76,Q64425,Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) (Fragment),Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) (Fragment),GO:0005576; GO:0016042; GO:0046872; GO:0004806,extracellular region; lipid catabolic process; metal ion binding; triglyceride lipase activity,PF00151;PF01477;,,,,,,,,,LIPP_MYOCO,Myocastor coypus (Coypu) (Nutria),lipid catabolic process [GO:0016042] comp133625_c0_seq1,969,48.5036,0.54643973,0,0,,1.00E-12,Q54ER4,Probable serine/threonine-protein kinase atr1 (EC 2.7.11.1) (Ataxia telangiectasia and rad3 related protein 1),Probable serine/threonine-protein kinase atr1 (EC 2.7.11.1) (Ataxia telangiectasia and rad3 related protein 1),GO:0005524; GO:0006281; GO:0000075; GO:0005634; GO:0004672; GO:0004674,ATP binding; DNA repair; cell cycle checkpoint; nucleus; protein kinase activity; protein serine/threonine kinase activity,PF02259;PF02260;PF00454;PF08064;,,,,,,,,,ATR1_DICDI,Dictyostelium discoideum (Slime mold),DNA repair [GO:0006281]; protein phosphorylation [GO:0006468] comp133625_c0_seq2,1571,48.5041,0.51118081,20,33,,0,Q9JLN9,Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1),GO:0005524; GO:0000139; GO:0016605; GO:0001030; GO:0001031; GO:0001032; GO:0031929; GO:0031931; GO:0031932; GO:0071456; GO:0031669; GO:0005829; GO:0008144; GO:0005789; GO:0007281; GO:0005764; GO:0070438; GO:0005741; GO:0051534; GO:0045792; GO:0016242; GO:0005634; GO:0018105; GO:0018107; GO:0030838; GO:0001938; GO:0010592; GO:0046889; GO:0010831; GO:0050731; GO:0051897; GO:0051496; GO:0045945; GO:0045727; GO:0046777; GO:0004674; GO:0032314; GO:0043610; GO:0031998; GO:0005979; GO:0045859; GO:0032095; GO:0043200; GO:0032868; GO:0043022; GO:0031529,ATP binding; Golgi membrane; PML body; RNA polymerase III type 1 promoter DNA binding; RNA polymerase III type 2 promoter DNA binding; RNA polymerase III type 3 promoter DNA binding; TOR signaling cascade; TORC1 complex; TORC2 complex; cellular response to hypoxia; cellular response to nutrient levels; cytosol; drug binding; endoplasmic reticulum membrane; germ cell development; lysosome; mTOR-FKBP12-rapamycin complex; mitochondrial outer membrane; negative regulation of NFAT protein import into nucleus; negative regulation of cell size; negative regulation of macroautophagy; nucleus; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; positive regulation of lamellipodium assembly; positive regulation of lipid biosynthetic process; positive regulation of myotube differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase III promoter; positive regulation of translation; protein autophosphorylation; protein serine/threonine kinase activity; regulation of Rac GTPase activity; regulation of carbohydrate utilization; regulation of fatty acid beta-oxidation; regulation of glycogen biosynthetic process; regulation of protein kinase activity; regulation of response to food; response to amino acid stimulus; response to insulin stimulus; ribosome binding; ruffle organization,PF11865;PF02259;PF02260;PF00454;PF08771;,0,CHOYP_MTOR.2.2,,,,,,,MTOR_MOUSE,Mus musculus (Mouse),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] comp133627_c0_seq1,641,40.0936,0.66744802,143,546,,2.00E-79,Q8C436,Protein-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase),Protein-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase),GO:0005737; GO:0018023; GO:0016279,cytoplasm; peptidyl-lysine trimethylation; protein-lysine N-methyltransferase activity,PF10294;,3.00E-20,CHOYP_METTL21D.1.1,,,,,,,MT21D_MOUSE,Mus musculus (Mouse),peptidyl-lysine trimethylation [GO:0018023] comp133634_c0_seq1,1815,41.7631,0.44458539,1752,67,,1.00E-134,A0JMY4,Basal body-orientation factor 1 (Coiled-coil domain-containing protein 176),Basal body-orientation factor 1 (Coiled-coil domain-containing protein 176),,,PF14988;,0,CHOYP_LOC100374467.1.1,2.00E-65,ruditapes_c22651,5.00E-104,CU682555.p.cg.6,5,,CN045_XENLA,Xenopus laevis (African clawed frog),motile cilium assembly [GO:0044458] comp133635_c0_seq1,903,30.897,0.52013873,73,153,,,,,,,,,,,3.00E-84,ruditapes2_c1060,,,,,,, comp133636_c0_seq1,1329,38.3747,0.55976463,52,68,,8.00E-31,Q07813,Apoptosis regulator BAX,Apoptosis regulator BAX,GO:0001783; GO:0001782; GO:0002358; GO:0002352; GO:0097144; GO:0060011; GO:0001777; GO:0006919; GO:0008635; GO:0097296; GO:0006309; GO:1902263; GO:1902262; GO:0001974; GO:0034644; GO:0071310; GO:0021987; GO:0015267; GO:0006922; GO:0005829; GO:0045136; GO:0005789; GO:0010248; GO:0097192; GO:0008625; GO:0009566; GO:0007281; GO:0035234; GO:0006687; GO:0048873; GO:0021854; GO:0072332; GO:0008630; GO:0070059; GO:0001822; GO:0008289; GO:0043653; GO:0008053; GO:0005741; GO:0005757; GO:0002262; GO:2001234; GO:0048147; GO:0043524; GO:0033137; GO:0032091; GO:0051402; GO:0001764; GO:0030264; GO:0005634; GO:0042475; GO:0001541; GO:0002904; GO:0060058; GO:0048087; GO:1900103; GO:2001241; GO:2001244; GO:0043525; GO:0032461; GO:0090200; GO:0051281; GO:0048597; GO:0042803; GO:0051260; GO:0001844; GO:0032471; GO:0051726; GO:0033599; GO:1902445; GO:0006808; GO:0043496; GO:0001836; GO:0032976; GO:0001101; GO:0048678; GO:0010332; GO:0009651; GO:0009636; GO:0060041; GO:1990009; GO:0046666; GO:0048515; GO:0070242; GO:0006927; GO:0060068,B cell apoptotic process; B cell homeostasis; B cell homeostatic proliferation; B cell negative selection; BAX complex; Sertoli cell proliferation; T cell homeostatic proliferation; activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; apoptotic DNA fragmentation; apoptotic process involved in embryonic digit morphogenesis; apoptotic process involved in patterning of blood vessels; blood vessel remodeling; cellular response to UV; cellular response to organic substance; cerebral cortex development; channel activity; cleavage of lamin involved in execution phase of apoptosis; cytosol; development of secondary sexual characteristics; endoplasmic reticulum membrane; establishment or maintenance of transmembrane electrochemical gradient; extrinsic apoptotic signaling pathway in absence of ligand; extrinsic apoptotic signaling pathway via death domain receptors; fertilization; germ cell development; germ cell programmed cell death; glycosphingolipid metabolic process; homeostasis of number of cells within a tissue; hypothalamus development; intrinsic apoptotic signaling pathway by p53 class mediator; intrinsic apoptotic signaling pathway in response to DNA damage; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; kidney development; lipid binding; mitochondrial fragmentation involved in apoptotic process; mitochondrial fusion; mitochondrial outer membrane; mitochondrial permeability transition pore complex; myeloid cell homeostasis; negative regulation of apoptotic signaling pathway; negative regulation of fibroblast proliferation; negative regulation of neuron apoptotic process; negative regulation of peptidyl-serine phosphorylation; negative regulation of protein binding; neuron apoptotic process; neuron migration; nuclear fragmentation involved in apoptotic nuclear change; nucleus; odontogenesis of dentin-containing tooth; ovarian follicle development; positive regulation of B cell apoptotic process; positive regulation of apoptotic process involved in mammary gland involution; positive regulation of developmental pigmentation; positive regulation of endoplasmic reticulum unfolded protein response; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of neuron apoptotic process; positive regulation of protein oligomerization; positive regulation of release of cytochrome c from mitochondria; positive regulation of release of sequestered calcium ion into cytosol; post-embryonic camera-type eye morphogenesis; protein homodimerization activity; protein homooligomerization; protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; reduction of endoplasmic reticulum calcium ion concentration; regulation of cell cycle; regulation of mammary gland epithelial cell proliferation; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death; regulation of nitrogen utilization; regulation of protein homodimerization activity; release of cytochrome c from mitochondria; release of matrix enzymes from mitochondria; response to acid; response to axon injury; response to gamma radiation; response to salt stress; response to toxic substance; retina development in camera-type eye; retinal cell apoptotic process; retinal cell programmed cell death; spermatid differentiation; thymocyte apoptotic process; transformed cell apoptotic process; vagina development,PF00452;,,,4.00E-40,ruditapes_c25303,,,,,BAX_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; apoptotic process involved in patterning of blood vessels [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell homeostatic proliferation [GO:0002358]; B cell negative selection [GO:0002352]; B cell receptor apoptotic signaling pathway [GO:1990117]; blood vessel remodeling [GO:0001974]; cell proliferation [GO:0008283]; cellular respiration [GO:0045333]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to organic substance [GO:0071310]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; development of secondary sexual characteristics [GO:0045136]; ectopic germ cell programmed cell death [GO:0035234]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fertilization [GO:0009566]; germ cell development [GO:0007281]; glial cell apoptotic process [GO:0034349]; glycosphingolipid metabolic process [GO:0006687]; homeostasis of number of cells [GO:0048872]; homeostasis of number of cells within a tissue [GO:0048873]; hypothalamus development [GO:0021854]; inner mitochondrial membrane organization [GO:0007007]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; leukocyte homeostasis [GO:0001776]; limb morphogenesis [GO:0035108]; male gonad development [GO:0008584]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein binding [GO:0032091]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; neuron migration [GO:0001764]; odontogenesis of dentin-containing tooth [GO:0042475]; outer mitochondrial membrane organization [GO:0007008]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of developmental pigmentation [GO:0048087]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902110]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; post-embryonic camera-type eye morphogenesis [GO:0048597]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]; protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:0001844]; protein oligomerization [GO:0051259]; regulation of cell cycle [GO:0051726]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of neuron apoptotic process [GO:0043523]; regulation of nitrogen utilization [GO:0006808]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; release of cytochrome c from mitochondria [GO:0001836]; release of matrix enzymes from mitochondria [GO:0032976]; response to axon injury [GO:0048678]; response to cocaine [GO:0042220]; response to copper ion [GO:0046688]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to ionizing radiation [GO:0010212]; response to salt stress [GO:0009651]; response to toxic substance [GO:0009636]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; retinal cell apoptotic process [GO:1990009]; retinal cell programmed cell death [GO:0046666]; Sertoli cell proliferation [GO:0060011]; sex differentiation [GO:0007548]; spermatid differentiation [GO:0048515]; spermatogenesis [GO:0007283]; T cell homeostatic proliferation [GO:0001777]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068] comp133639_c0_seq1,1148,33.5366,0.40726937,1166,14,,2.00E-10,A4IFD0,Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5),Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5),GO:0005524; GO:0046034; GO:0004017; GO:0005813; GO:0005737; GO:0004550; GO:0019206; GO:0009142,ATP binding; ATP metabolic process; adenylate kinase activity; centrosome; cytoplasm; nucleoside diphosphate kinase activity; nucleoside kinase activity; nucleoside triphosphate biosynthetic process,,,,,,,,,,KAD5_BOVIN,Bos taurus (Bovine),ATP metabolic process [GO:0046034]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp133641_c0_seq1,849,46.9965,0.65708193,37,533,,2.00E-96,P50867,Cysteine synthase (CSase) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase) (OAS-TL) (O-acetylserine sulfhydrylase),Cysteine synthase 1 (CS 1) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase 1) (OAS-TL 1) (O-acetylserine sulfhydrylase 1),GO:0019280; GO:0004122; GO:0006535; GO:0019343; GO:0004124; GO:0005622; GO:0016740; GO:0019346,L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine; cystathionine beta-synthase activity; cysteine biosynthetic process from serine; cysteine biosynthetic process via cystathionine; cysteine synthase activity; intracellular; transferase activity; transsulfuration,PF00291;,8.00E-131,CHOYP_LOC100377160.2.2,,,,,,,CYSK_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),cellular amino acid biosynthetic process [GO:0008652]; cysteine biosynthetic process from serine [GO:0006535] comp133641_c1_seq1,389,40.3599,0.39130693,24,308,,3.00E-06,Q59918,Cysteine synthase (CSase) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase) (OAS-TL) (O-acetylserine sulfhydrylase) (Fragment),Cysteine synthase (CSase) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase) (OAS-TL) (O-acetylserine sulfhydrylase) (Fragment),GO:0004124; GO:0016740,cysteine synthase activity; transferase activity,PF00291;,,,,,,,,,CYSK_STAHA,Staphylococcus haemolyticus, comp133642_c0_seq3,779,35.8151,1.0909674,2,107,,4.00E-10,Q99999,Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase),Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase),GO:0000139; GO:0006682; GO:0001733; GO:0006687; GO:0005887; GO:0042552; GO:0006487; GO:0044281; GO:0007283; GO:0008146,Golgi membrane; galactosylceramide biosynthetic process; galactosylceramide sulfotransferase activity; glycosphingolipid metabolic process; integral to plasma membrane; myelination; protein N-linked glycosylation; small molecule metabolic process; spermatogenesis; sulfotransferase activity,PF06990;,,,,,,,,,G3ST1_HUMAN,Homo sapiens (Human),galactosylceramide biosynthetic process [GO:0006682]; myelination [GO:0042552]; protein N-linked glycosylation [GO:0006487]; spermatogenesis [GO:0007283] comp133644_c0_seq3,1917,47.3657,0.31084992,28,146,,2.00E-26,Q4R361,E3 ubiquitin-protein ligase ZNF645 (EC 6.3.2.-) (Zinc finger protein 645),E3 ubiquitin-protein ligase ZNF645 (EC 6.3.2.-) (Zinc finger protein 645),GO:0005737; GO:0016874; GO:0016567; GO:0008270,cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,,5.00E-49,CHOYP_LOC100864501.1.1,,,,,,,ZN645_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein ubiquitination [GO:0016567] comp133644_c0_seq4,1893,47.2266,0.3166134,0,8,,7.00E-35,Q9JIY2,E3 ubiquitin-protein ligase Hakai (EC 6.3.2.-) (Casitas B-lineage lymphoma-transforming sequence-like protein 1) (E-cadherin binding protein E7) (c-Cbl-like protein 1),E3 ubiquitin-protein ligase Hakai (EC 6.3.2.-) (Casitas B-lineage lymphoma-transforming sequence-like protein 1) (E-cadherin binding protein E7) (c-Cbl-like protein 1),GO:0016337; GO:0007162; GO:0030335; GO:0045807; GO:0004842; GO:0008270,cell-cell adhesion; negative regulation of cell adhesion; positive regulation of cell migration; positive regulation of endocytosis; ubiquitin-protein ligase activity; zinc ion binding,,5.00E-49,CHOYP_LOC100864501.1.1,,,,,,,HAKAI_MOUSE,Mus musculus (Mouse),negative regulation of cell adhesion [GO:0007162]; positive regulation of cell migration [GO:0030335]; positive regulation of endocytosis [GO:0045807]; single organismal cell-cell adhesion [GO:0016337] comp133646_c0_seq1,687,48.6172,0.91486268,0,0,,,,,,,,,5.00E-18,CHOYP_LOC100744369.1.1,,,,,,,,, comp133646_c0_seq3,1151,48.2189,0.81226395,0,0,,,,,,,,,3.00E-18,CHOYP_ISCW_ISCW018106.1.1,,,,,,,,, comp133646_c0_seq5,1390,48.0576,0.7883789,0,0,,2.00E-46,Q5R4H4,Epidermal growth factor receptor kinase substrate 8,Epidermal growth factor receptor kinase substrate 8,GO:0048365; GO:0016601; GO:0003779; GO:0051764; GO:0051017; GO:0070358; GO:0051016; GO:0005938; GO:0036336; GO:0010458; GO:0030426; GO:0008360; GO:0032587; GO:0032420,Rac GTPase binding; Rac protein signal transduction; actin binding; actin crosslink formation; actin filament bundle assembly; actin polymerization-dependent cell motility; barbed-end actin filament capping; cell cortex; dendritic cell migration; exit from mitosis; growth cone; regulation of cell shape; ruffle membrane; stereocilium,PF08416;PF00018;,,,,,,,,,EPS8_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin polymerization-dependent cell motility [GO:0070358]; barbed-end actin filament capping [GO:0051016]; dendritic cell migration [GO:0036336]; exit from mitosis [GO:0010458]; Rac protein signal transduction [GO:0016601]; regulation of actin filament length [GO:0030832]; regulation of cell shape [GO:0008360] comp133646_c0_seq6,926,48.2721,0.8546186,0,0,,2.00E-16,Q8TE67,Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3),Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3),GO:0005737,cytoplasm,PF08416;PF00018;,3.00E-54,CHOYP_LOC100744369.1.1,,,,,,,ES8L3_HUMAN,Homo sapiens (Human), comp133649_c1_seq2,299,43.4783,0.29240093,2,0,,2.00E-29,Q10185,ATP-binding cassette transporter abc2 (ABC transporter abc2) (EC 3.6.3.-) (ATP-energized glutathione S-conjugate pump abc2) (Glutathione S-conjugate-transporting ATPase abc2),ATP-binding cassette transporter abc2 (ABC transporter abc2) (EC 3.6.3.-) (ATP-energized glutathione S-conjugate pump abc2) (Glutathione S-conjugate-transporting ATPase abc2),GO:0005524; GO:0005794; GO:0071276; GO:0000329; GO:0071997; GO:0071996; GO:0016021; GO:0071995; GO:0071992; GO:0009636,ATP binding; Golgi apparatus; cellular response to cadmium ion; fungal-type vacuole membrane; glutathione S-conjugate-transporting ATPase activity; glutathione transmembrane import into vacuole; integral to membrane; phytochelatin import into vacuole; phytochelatin transmembrane transporter activity; response to toxic substance,PF00664;PF00005;,,,,,,,,,ABC2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular detoxification of cadmium ion [GO:0098849]; glutathione transmembrane import into vacuole [GO:0071996]; phytochelatin 2 import into vacuole [GO:0036246] comp133649_c1_seq3,337,46.2908,0.50033335,14,7,,5.00E-39,O15440,Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP) (pABC11),Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP) (pABC11),GO:0005524; GO:0006200; GO:0042626; GO:0005975; GO:0030213; GO:0005887; GO:0008514,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; carbohydrate metabolic process; hyaluronan biosynthetic process; integral to plasma membrane; organic anion transmembrane transporter activity",PF00664;PF00005;,,,,,,,,,MRP5_HUMAN,Homo sapiens (Human),hyaluronan biosynthetic process [GO:0030213]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp133649_c2_seq1,345,48.9855,0.610773,0,0,,,,,,,,,1.00E-21,CHOYP_MRP1.6.10,,,,,,,,, comp133649_c2_seq2,1443,45.9459,0.55571057,41,9,,2.00E-113,O15440,Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP) (pABC11),Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP) (pABC11),GO:0005524; GO:0006200; GO:0042626; GO:0005975; GO:0030213; GO:0005887; GO:0008514,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; carbohydrate metabolic process; hyaluronan biosynthetic process; integral to plasma membrane; organic anion transmembrane transporter activity",PF00664;PF00005;,,,,,,,,,MRP5_HUMAN,Homo sapiens (Human),hyaluronan biosynthetic process [GO:0030213]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp133649_c2_seq3,812,47.2906,0.53399096,3,0,,1.00E-61,Q96J66,ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8),ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0055085,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; transmembrane transport",PF00664;PF00005;,1.00E-27,CHOYP_MRP5.3.3,,,,,,,ABCCB_HUMAN,Homo sapiens (Human),organic anion transport [GO:0015711]; purine nucleotide transport [GO:0015865]; transmembrane transport [GO:0055085] comp133649_c3_seq1,205,41.9512,0.34955583,9,9,,,,,,,,,3.00E-40,CHOYP_MRP5.1.3,,,,,,,,, comp133651_c0_seq1,863,41.0197,0.79349359,5,45,,2.00E-10,O00533,Neural cell adhesion molecule L1-like protein (Close homolog of L1) [Cleaved into: Processed neural cell adhesion molecule L1-like protein],Neural cell adhesion molecule L1-like protein (Close homolog of L1) [Cleaved into: Processed neural cell adhesion molecule L1-like protein],GO:0008344; GO:0045177; GO:0007411; GO:0007155; GO:0050890; GO:0030425; GO:0035640; GO:0016021; GO:0043524; GO:0001764; GO:0005886; GO:0005578; GO:0007165,adult locomotory behavior; apical part of cell; axon guidance; cell adhesion; cognition; dendrite; exploration behavior; integral to membrane; negative regulation of neuron apoptotic process; neuron migration; plasma membrane; proteinaceous extracellular matrix; signal transduction,PF13882;PF00041;PF07679;PF00047;,,,,,,,,,CHL1_HUMAN,Homo sapiens (Human),adult locomotory behavior [GO:0008344]; axon guidance [GO:0007411]; axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; cognition [GO:0050890]; exploration behavior [GO:0035640]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; signal transduction [GO:0007165] comp133651_c0_seq2,866,41.224,0.78639561,5,40,,6.00E-12,P20241,Neuroglian,Neuroglian,GO:0008366; GO:0048675; GO:0005509; GO:0061343; GO:0048036; GO:0048813; GO:0007173; GO:0060857; GO:0008050; GO:0030175; GO:0007560; GO:0016021; GO:0016328; GO:0008049; GO:0035011; GO:0016319; GO:0021682; GO:0007158; GO:0005919; GO:0045924; GO:0035151; GO:0019991; GO:0050808; GO:0005923,"axon ensheathment; axon extension; calcium ion binding; cell adhesion involved in heart morphogenesis; central complex development; dendrite morphogenesis; epidermal growth factor receptor signaling pathway; establishment of glial blood-brain barrier; female courtship behavior; filopodium; imaginal disc morphogenesis; integral to membrane; lateral plasma membrane; male courtship behavior; melanotic encapsulation of foreign target; mushroom body development; nerve maturation; neuron cell-cell adhesion; pleated septate junction; regulation of female receptivity; regulation of tube size, open tracheal system; septate junction assembly; synapse organization; tight junction",PF13882;PF00041;PF07679;PF00047;,,,,,,,,,NRG_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" comp133653_c0_seq1,1152,41.5799,0.40498801,73,334,,3.00E-20,Q0P426,Spindle and kinetochore-associated protein 2 (Protein FAM33A),Spindle and kinetochore-associated protein 2 (Protein FAM33A),GO:0051301; GO:0007059; GO:0000940; GO:0005737; GO:0008017; GO:0007067; GO:0031110; GO:0005876,cell division; chromosome segregation; condensed chromosome outer kinetochore; cytoplasm; microtubule binding; mitosis; regulation of microtubule polymerization or depolymerization; spindle microtubule,PF11362;PF16740;,9.00E-18,CHOYP_LOC100894033.1.1,,,,,,,SKA2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; regulation of microtubule polymerization or depolymerization [GO:0031110] comp133655_c2_seq1,6399,41.1314,0.72044523,5,6430,female>male,7.00E-30,O36966,Replicase polyprotein [Cleaved into: Protein 1A; Protein 2A; Protein 2B; Protein 2C; Protein 3A; Protein 3B; 3C-like protease (EC 3.4.22.-); RNA-directed RNA polymerase 3D-POL (EC 2.7.7.48)],Replicase polyprotein [Cleaved into: Protein 1A; Protein 2A; Protein 2B; Protein 2C; Protein 3A; Protein 3B; 3C-like protease (EC 3.4.22.-); RNA-directed RNA polymerase 3D-POL (EC 2.7.7.48)],GO:0005524; GO:0003723; GO:0003724; GO:0003968; GO:0004197; GO:0006508; GO:0006351; GO:0019079,"ATP binding; RNA binding; RNA helicase activity; RNA-directed RNA polymerase activity; cysteine-type endopeptidase activity; proteolysis; transcription, DNA-dependent; viral genome replication",PF12381;PF00680;PF00910;,,,0,ruditapes_c703,,,,,POLN_DCVEB,Drosophila C virus (strain EB) (DCV),"transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]" comp133657_c0_seq1,1304,37.3466,0.64752829,18,41,,4.00E-14,Q05024,Protein TRI1,Protein TRI1,GO:0003677; GO:0005737; GO:0005730; GO:0006355; GO:0006351,"DNA binding; cytoplasm; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08766;PF02201;,,,,,,,,,TRI1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133657_c0_seq2,821,35.5664,0.59738461,0,0,,5.00E-10,Q08747,Upstream activation factor subunit UAF30 (Upstream activation factor 30 KDa subunit) (p30),Upstream activation factor subunit UAF30 (Upstream activation factor 30 KDa subunit) (p30),GO:0000500; GO:0001165; GO:0006325; GO:0006355; GO:0042790,"RNA polymerase I upstream activating factor complex; RNA polymerase I upstream control element sequence-specific DNA binding; chromatin organization; regulation of transcription, DNA-dependent; transcription of nuclear large rRNA transcript from RNA polymerase I promoter",PF08766;PF02201;,3.00E-22,CHOYP_LOC654949.1.1,,,,,,,UAF30_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),chromatin organization [GO:0006325]; regulation of transcription from RNA polymerase I promoter [GO:0006356]; transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:0042790] comp133659_c0_seq1,1325,38.717,0.56869805,71,249,,1.00E-108,Q5XH14,V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1),V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1),GO:0015991; GO:0015078; GO:0033180,"ATP hydrolysis coupled proton transport; hydrogen ion transmembrane transporter activity; proton-transporting V-type ATPase, V1 domain",PF03223;,1.00E-73,CHOYP_VATC1.1.1,,,,,,,VATC1_XENLA,Xenopus laevis (African clawed frog),ATP hydrolysis coupled proton transport [GO:0015991] comp133661_c0_seq1,3196,41.6771,0.37667417,378,119,,1.00E-55,Q8MQJ9,Brain tumor protein,Brain tumor protein,GO:0008356; GO:0055060; GO:0007411; GO:0007420; GO:0005737; GO:0007402; GO:0007406; GO:0048477; GO:0006909; GO:0009303; GO:0035282; GO:0030371; GO:0008270,asymmetric cell division; asymmetric neuroblast division resulting in ganglion mother cell formation; axon guidance; brain development; cytoplasm; ganglion mother cell fate determination; negative regulation of neuroblast proliferation; oogenesis; phagocytosis; rRNA transcription; segmentation; translation repressor activity; zinc ion binding,PF01436;PF00643;,0,CHOYP_LOC100882263.1.1,,,,,,,BRAT_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419] comp133661_c0_seq3,1108,39.8014,0.29678068,9,4,,4.00E-07,A0JNG4,RING finger protein 207,RING finger protein 207,GO:0005622; GO:0008270,intracellular; zinc ion binding,PF00643;PF00097;,,,,,,,,,RN207_BOVIN,Bos taurus (Bovine), comp133661_c0_seq5,1936,40.6508,0.33784893,5,3,,1.00E-32,Q6PFY8,Tripartite motif-containing protein 45,Tripartite motif-containing protein 45,GO:0060348; GO:0005737; GO:0005634; GO:0008270,bone development; cytoplasm; nucleus; zinc ion binding,PF00630;PF00643;PF13445;,,,,,,,,,TRI45_MOUSE,Mus musculus (Mouse),bone development [GO:0060348] comp133667_c0_seq1,2127,42.1721,0.37446714,81,320,,4.00E-103,Q17RS7,Flap endonuclease GEN homolog 1 (EC 3.1.-.-),Flap endonuclease GEN homolog 1 (EC 3.1.-.-),GO:0003677; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF00867;PF00752;,1.00E-51,CHOYP_GEN1.1.1,,,,,,,GEN_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] comp133671_c0_seq1,1671,41.1131,0.70731269,118,453,,1.00E-100,O55033,Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta),Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta),GO:0007015; GO:0016477; GO:0005783; GO:0030032; GO:0042102; GO:0030838; GO:0045944; GO:0006417; GO:0012506,actin filament organization; cell migration; endoplasmic reticulum; lamellipodium assembly; positive regulation of T cell proliferation; positive regulation of actin filament polymerization; positive regulation of transcription from RNA polymerase II promoter; regulation of translation; vesicle membrane,PF00017;PF00018;PF14604;,1.00E-69,CHOYP_LOC100533447.2.3,,,,,,,NCK2_MOUSE,Mus musculus (Mouse),actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; vesicle-mediated transport [GO:0016192] comp133672_c0_seq5,1028,45.3307,0.68482123,29,154,,2.00E-10,Q5RDA9,F-box only protein 42,F-box only protein 42,,,PF12937;PF07646;,3.00E-16,CHOYP_FBX42.1.1,,,,,,,FBX42_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp133674_c0_seq1,1156,39.7059,0.42258778,173,1276,,3.00E-14,Q9P6J4,Uncharacterized protein C1683.06c,Uncharacterized protein C1683.06c,GO:0034356; GO:0005829; GO:0070635; GO:0019358; GO:0070636; GO:0005634; GO:0046135; GO:0008655; GO:0045437,NAD biosynthesis via nicotinamide riboside salvage pathway; cytosol; nicotinamide riboside hydrolase activity; nicotinate nucleotide salvage; nicotinic acid riboside hydrolase activity; nucleus; pyrimidine nucleoside catabolic process; pyrimidine-containing compound salvage; uridine nucleosidase activity,PF01156;,,,,,,,,,YHD6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinate nucleotide salvage [GO:0019358]; purine nucleoside catabolic process [GO:0006152]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside catabolic process [GO:0046135] comp133683_c0_seq2,1998,41.2913,0.37302867,19,35,,,,,,,,,8.00E-15,CHOYP_contig_004795,3.00E-43,ruditapes_c21963,,,,,,, comp133684_c2_seq1,1948,39.7331,0.60199575,41,29,,6.00E-43,Q6ZSM3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_HUMAN,Homo sapiens (Human),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp133684_c2_seq2,1253,41.66,0.63078511,0,0,,,,,,,,,2.00E-20,CHOYP_LOC100881530.1.1,,,,,,,,, comp133684_c2_seq3,1434,40.9344,0.60669436,0,0,,1.00E-35,Q7RTX9,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT14_HUMAN,Homo sapiens (Human), comp133686_c0_seq1,2286,46.0192,0.69311394,58,29,,7.00E-62,Q6PAR5,GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6),GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6),GO:0032794; GO:0005096; GO:0005829; GO:0006897; GO:0005768; GO:0005085; GO:0016020; GO:0043547; GO:0051223; GO:0051056; GO:0007165,GTPase activating protein binding; GTPase activator activity; cytosol; endocytosis; endosome; guanyl-nucleotide exchange factor activity; membrane; positive regulation of GTPase activity; regulation of protein transport; regulation of small GTPase mediated signal transduction; signal transduction,PF00616;PF02204;,5.00E-69,CHOYP_LOC100866049.1.1,,,,,,,GAPD1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165] comp133686_c0_seq2,1194,48.0737,0.68058337,0,0,,,,,,,,,2.00E-69,CHOYP_LOC100866049.1.1,,,,,,,,, comp133687_c0_seq1,3239,33.251,0.50943401,5970,23365,,0,P48463,Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16),Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16),GO:0000775; GO:0005737; GO:0046872; GO:0043066; GO:0005634; GO:0004721; GO:0043161; GO:0046982; GO:0000159; GO:0010468; GO:0046677; GO:0042542; GO:0000922,"chromosome, centromeric region; cytoplasm; metal ion binding; negative regulation of apoptotic process; nucleus; phosphoprotein phosphatase activity; proteasomal ubiquitin-dependent protein catabolic process; protein heterodimerization activity; protein phosphatase type 2A complex; regulation of gene expression; response to antibiotic; response to hydrogen peroxide; spindle pole",PF00149;,0,CHOYP_SELD.1.2,5.00E-119,ruditapes_c13481,,,,,PP2AA_CHICK,Gallus gallus (Chicken), comp133689_c0_seq1,474,30.1688,0.9368878,2,71,,,,,,,,,,,5.00E-20,ruditapes2_c1555,,,,,,, comp133693_c0_seq1,1557,39.2421,0.45238114,0,0,,1.00E-122,Q8R173,Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3),Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3),GO:0005794; GO:0000139; GO:0016021; GO:0016409; GO:0018345; GO:0006605; GO:0008270,Golgi apparatus; Golgi membrane; integral to membrane; palmitoyltransferase activity; protein palmitoylation; protein targeting; zinc ion binding,PF01529;,1.00E-100,CHOYP_BRAFLDRAFT_218835.1.2,,,,,,,ZDHC3_MOUSE,Mus musculus (Mouse),protein palmitoylation [GO:0018345]; protein targeting [GO:0006605] comp133693_c0_seq2,1575,38.6667,0.42706341,0,0,,,,,,,,,1.00E-99,CHOYP_BRAFLDRAFT_218835.2.2,,,,,,,,, comp133693_c0_seq3,613,43.5563,0.65790836,0,0,,3.00E-73,Q8R173,Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3),Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3),GO:0005794; GO:0000139; GO:0016021; GO:0016409; GO:0018345; GO:0006605; GO:0008270,Golgi apparatus; Golgi membrane; integral to membrane; palmitoyltransferase activity; protein palmitoylation; protein targeting; zinc ion binding,PF01529;,,,,,,,,,ZDHC3_MOUSE,Mus musculus (Mouse),protein palmitoylation [GO:0018345]; protein targeting [GO:0006605] comp133693_c0_seq4,631,41.9968,0.61747282,0,0,,,,,,,,,1.00E-12,CHOYP_BRAFLDRAFT_223325.1.1,,,,,,,,, comp133696_c1_seq1,1166,42.5386,1.04442352,28,289,,5.00E-49,Q6DDL7,Protein unc-93 homolog A (Unc-93A),Protein unc-93 homolog A (Unc-93A),GO:0016021,integral to membrane,PF05978;,,,,,,,,,UN93A_XENLA,Xenopus laevis (African clawed frog), comp133701_c0_seq1,944,39.3008,0.32955573,142,670,,2.00E-47,P51398,"28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein)","28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein)",GO:0008637; GO:0097190; GO:0005761; GO:0005739; GO:0005730; GO:0015935,apoptotic mitochondrial changes; apoptotic signaling pathway; mitochondrial ribosome; mitochondrion; nucleolus; small ribosomal subunit,PF10236;,,,,,,,,,RT29_HUMAN,Homo sapiens (Human),apoptotic signaling pathway [GO:0097190]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126] comp133701_c1_seq2,570,37.7193,0.26178331,18,53,,,,,,,,,,,4.00E-23,ruditapes_c15133,,,,,,, comp133706_c0_seq1,1467,40.7635,0.81179761,464,3169,,0,Q9H0S4,Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47),Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0008625; GO:0006397; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; extrinsic apoptotic signaling pathway via death domain receptors; mRNA processing; nucleolus; rRNA processing,PF00270;PF00271;,0,CHOYP_DDX47.1.1,3.00E-17,ruditapes_c15859,,,,,DDX47_HUMAN,Homo sapiens (Human),extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] comp133709_c0_seq1,1672,39.8325,0.5183675,4064,27334,,0,Q3B8M3,Eukaryotic translation initiation factor 3 subunit E-B (eIF3e-B) (Eukaryotic translation initiation factor 3 subunit 6-B),Eukaryotic translation initiation factor 3 subunit E-B (eIF3e-B) (Eukaryotic translation initiation factor 3 subunit 6-B),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0005634; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; nucleus; regulation of translational initiation; translation initiation factor activity; translational initiation,PF09440;PF01399;,0,CHOYP_EIF3E.1.1,2.00E-127,ruditapes2_c2226,,,,,EI3EB_XENLA,Xenopus laevis (African clawed frog),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp133712_c1_seq1,689,39.3324,0.52931618,2,0,,2.00E-10,O15945,Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango),Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango),GO:0007420; GO:0071456; GO:0032869; GO:0005737; GO:0048813; GO:0007425; GO:0008347; GO:0007517; GO:0000122; GO:0005634; GO:0048477; GO:0007422; GO:0045944; GO:0043234; GO:0046982; GO:0045676; GO:0043565; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"brain development; cellular response to hypoxia; cellular response to insulin stimulus; cytoplasm; dendrite morphogenesis; epithelial cell fate determination, open tracheal system; glial cell migration; muscle organ development; negative regulation of transcription from RNA polymerase II promoter; nucleus; oogenesis; peripheral nervous system development; positive regulation of transcription from RNA polymerase II promoter; protein complex; protein heterodimerization activity; regulation of R7 cell differentiation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;PF00989;,,,,,,,,,ARNT_DROME,Drosophila melanogaster (Fruit fly),"brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; epithelial cell fate determination, open tracheal system [GO:0007425]; glial cell migration [GO:0008347]; limb development [GO:0060173]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of R7 cell differentiation [GO:0045676]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]" comp133712_c1_seq3,2828,43.529,0.62730592,100,156,,3.00E-54,Q61026,Nuclear receptor coactivator 2 (NCoA-2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1) (Transcriptional intermediary factor 2),Nuclear receptor coactivator 2 (NCoA-2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1) (Steroid receptor coactivator 2) (SRC-2) (Transcriptional intermediary factor 2),GO:0003682; GO:0005737; GO:0016573; GO:0004402; GO:0000122; GO:0005654; GO:0045944; GO:0005102; GO:0004871; GO:0030375; GO:0006351,"chromatin binding; cytoplasm; histone acetylation; histone acetyltransferase activity; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; receptor binding; signal transducer activity; thyroid hormone receptor coactivator activity; transcription, DNA-dependent",PF07469;PF16279;PF08815;PF00989;PF08832;,5.00E-76,CHOYP_ISCW_ISCW017872.2.2,,,,,,,NCOA2_MOUSE,Mus musculus (Mouse),"cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; intracellular receptor signaling pathway [GO:0030522]; locomotor rhythm [GO:0045475]; male gonad development [GO:0008584]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of female receptivity [GO:0045925]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133717_c1_seq5,642,37.0717,0.59537181,0,0,,9.00E-09,Q5XFZ0,UPF0711 protein C18orf21 homolog,UPF0711 protein C18orf21 homolog,,,PF15719;,,,,,,,,,CR021_MOUSE,Mus musculus (Mouse), comp133719_c0_seq1,658,31.9149,0.12064101,57,193,,2.00E-23,Q9NWQ9,Uncharacterized protein C14orf119,Uncharacterized protein C14orf119,GO:0005739,mitochondrion,PF14969;,3.00E-20,CHOYP_SI_CH211-14A17.11.1.1,3.00E-44,ruditapes_c19557,,,,,CN119_HUMAN,Homo sapiens (Human), comp133723_c0_seq1,1533,38.1605,0.43137365,297,697,,7.00E-79,Q5PQN9,"39S ribosomal protein L38, mitochondrial (L38mt) (MRP-L38)","39S ribosomal protein L38, mitochondrial (L38mt) (MRP-L38)",GO:0015629; GO:0005739; GO:0005840,actin cytoskeleton; mitochondrion; ribosome,PF01161;,6.00E-15,CHOYP_LOC100741487.1.1,,,,,,,RM38_RAT,Rattus norvegicus (Rat), comp133725_c0_seq2,378,41.5344,0.12524873,0,0,,5.00E-06,Q16994,Antho-RFamide neuropeptides type 2 [Cleaved into: Antho-RFamide],Antho-RFamide neuropeptides type 2 [Cleaved into: Antho-RFamide],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,,,,,,,,,FMR2_ANTEL,Anthopleura elegantissima (Sea anemone),neuropeptide signaling pathway [GO:0007218] comp133730_c3_seq1,329,45.8967,0.53131081,13,15,,3.00E-24,Q14AT5,Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G),Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G),GO:0005254; GO:0005783; GO:0016021; GO:0005634; GO:0005886,chloride channel activity; endoplasmic reticulum; integral to membrane; nucleus; plasma membrane,PF16178;PF04547;,,,,,,,,,ANO7_MOUSE,Mus musculus (Mouse),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821] comp133730_c8_seq1,678,43.3628,0.56878381,49,12,,2.00E-87,Q6IWH7,Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G),Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G),GO:0030054; GO:0005254; GO:0005829; GO:0005783; GO:0016021; GO:0034220; GO:0005634; GO:0005886,cell junction; chloride channel activity; cytosol; endoplasmic reticulum; integral to membrane; ion transmembrane transport; nucleus; plasma membrane,PF16178;PF04547;,4.00E-127,CHOYP_LOC100906981.1.1,,,,,,,ANO7_HUMAN,Homo sapiens (Human),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220] comp133733_c0_seq2,739,37.4831,0.9197757,68,0,,,,,,,,,1.00E-13,CHOYP_RAB7A.2.2,,,,,,,,, comp133733_c0_seq6,262,46.1832,0.79088085,8,0,,,,,,,,,8.00E-17,CHOYP_RAB7A.2.2,2.00E-22,ruditapes2_c272,,,,,,, comp133734_c0_seq2,1219,38.3101,0.6184526,0,0,,9.00E-83,P97328,Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),GO:0005524; GO:0005737; GO:0006000; GO:0004454,ATP binding; cytoplasm; fructose metabolic process; ketohexokinase activity,PF00294;,,,,,,,,,KHK_MOUSE,Mus musculus (Mouse),fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; glycolytic process through fructose-1-phosphate [GO:0061625]; regulation of glycogen metabolic process [GO:0070873] comp133734_c0_seq3,1187,38.2477,0.61671203,0,0,,7.00E-83,P97328,Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),GO:0005524; GO:0005737; GO:0006000; GO:0004454,ATP binding; cytoplasm; fructose metabolic process; ketohexokinase activity,PF00294;,,,,,,,,,KHK_MOUSE,Mus musculus (Mouse),fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; glycolytic process through fructose-1-phosphate [GO:0061625]; regulation of glycogen metabolic process [GO:0070873] comp133735_c0_seq1,617,36.7909,0.67383355,6,182,,3.00E-24,P22629,Streptavidin,Streptavidin,GO:0005576,extracellular region,PF01382;,,,2.00E-20,ruditapes_c9154,,,,,SAV_STRAV,Streptomyces avidinii, comp133740_c0_seq10,977,43.2958,0.61982863,0,0,,9.00E-143,B0R0T1,von Willebrand factor A domain-containing protein 8,von Willebrand factor A domain-containing protein 8,GO:0005524; GO:0006200; GO:0016887,ATP binding; ATP catabolic process; ATPase activity,PF07728;,4.00E-78,CHOYP_VWA8.2.3,,,,,,,VWA8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp133740_c0_seq6,1510,46.0927,0.5303529,0,0,,0,B0R0T1,von Willebrand factor A domain-containing protein 8,von Willebrand factor A domain-containing protein 8,GO:0005524; GO:0006200; GO:0016887,ATP binding; ATP catabolic process; ATPase activity,PF07728;,2.00E-102,CHOYP_VWA8.2.3,,,,,,,VWA8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp133741_c1_seq1,1532,40.47,0.52749647,87,339,,6.00E-67,Q5D1E8,Ribonuclease ZC3H12A (EC 3.1.-.-) (MCP-induced protein 1) (Zinc finger CCCH domain-containing protein 12A),Bifunctional endoribonuclease and deubiquitinase ZC3H12A [Includes: Endoribonuclease ZC3H12A (EC 3.1.-.-); Deubiquitinase ZC3H12A (EC 3.4.19.12) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A)],GO:0001525; GO:0006915; GO:0030154; GO:0071222; GO:0005737; GO:0004519; GO:0046872; GO:0032088; GO:0010629; GO:0032715; GO:0043031; GO:0045019; GO:0032720; GO:0090305; GO:0005634; GO:0005886; GO:0010508; GO:0045600; GO:0010628; GO:0010884; GO:2000379,angiogenesis; apoptotic process; cell differentiation; cellular response to lipopolysaccharide; cytoplasm; endonuclease activity; metal ion binding; negative regulation of NF-kappaB transcription factor activity; negative regulation of gene expression; negative regulation of interleukin-6 production; negative regulation of macrophage activation; negative regulation of nitric oxide biosynthetic process; negative regulation of tumor necrosis factor production; nucleic acid phosphodiester bond hydrolysis; nucleus; plasma membrane; positive regulation of autophagy; positive regulation of fat cell differentiation; positive regulation of gene expression; positive regulation of lipid storage; positive regulation of reactive oxygen species metabolic process,PF11977;,1.00E-30,CHOYP_LOC100080726.1.1,,,,,,,ZC12A_HUMAN,Homo sapiens (Human),"3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of macrophage activation [GO:0043031]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deubiquitination [GO:0016579]; protein oligomerization [GO:0051259]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; transcription, DNA-templated [GO:0006351]" comp133746_c0_seq1,994,41.5493,1.08997062,102,138,,8.00E-76,Q95ZJ1,Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),GO:0000139; GO:0016021; GO:0004653; GO:0018243,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation via threonine,PF00535;PF00652;,8.00E-24,CHOYP_CBR-GLY-5.1.1,,,,,,,GALT5_CAEEL,Caenorhabditis elegans,protein O-linked glycosylation via threonine [GO:0018243] comp133755_c1_seq2,592,44.5946,1.10531536,14,51,,3.00E-29,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp133757_c1_seq1,1880,42.8723,0.38462693,115,108,,2.00E-23,F1NPG5,Centromere protein T (CENP-T),Centromere protein T (CENP-T),GO:0003677; GO:0051301; GO:0007059; GO:0000777; GO:0051382; GO:0007067; GO:0005634,DNA binding; cell division; chromosome segregation; condensed chromosome kinetochore; kinetochore assembly; mitosis; nucleus,PF16171;,,,,,,,,,CENPT_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic nuclear division [GO:0007067] comp133759_c0_seq2,616,42.0455,0.40689556,9,0,,,,,,,,,1.00E-68,CHOYP_LOC661787.1.1,,,,,,,,, comp133759_c0_seq3,1038,40.9441,0.41359566,3,1,,,,,,,,,5.00E-90,CHOYP_LOC100740578.1.1,,,,,,,,, comp133759_c0_seq4,2321,38.7764,0.41844523,20,33,,8.00E-52,Q04870,General transcription factor IIF subunit 1 (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74),General transcription factor IIF subunit 1 (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74),GO:0003677; GO:0005634; GO:0045893; GO:0006367; GO:0016740,"DNA binding; nucleus; positive regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter; transferase activity",PF05793;,,,,,,,,,T2FA_XENLA,Xenopus laevis (African clawed frog),positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp133762_c0_seq1,1139,37.2256,0.51388428,2,26,,7.00E-63,Q66HC4,Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74),Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74),GO:0016311; GO:0046872; GO:0033883,dephosphorylation; metal ion binding; pyridoxal phosphatase activity,PF06888;,,,,,,,,,PHOP2_RAT,Rattus norvegicus (Rat), comp133762_c0_seq2,1128,37.234,0.49398989,3,32,,8.00E-63,Q66HC4,Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74),Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74),GO:0016311; GO:0046872; GO:0033883,dephosphorylation; metal ion binding; pyridoxal phosphatase activity,PF06888;,,,,,,,,,PHOP2_RAT,Rattus norvegicus (Rat), comp133763_c0_seq1,1126,39.6092,0.89101816,19,72,,3.00E-25,Q8JG33,WAP four-disulfide core domain protein 1 (Protein ps20),WAP four-disulfide core domain protein 1 (Protein ps20),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00095;,,,,,,,,,WFDC1_CHICK,Gallus gallus (Chicken),negative regulation of inflammatory response [GO:0050728]; negative regulation of wound healing [GO:0061045]; regulation of cell growth [GO:0001558] comp133765_c0_seq1,1209,34.4913,0.62164351,0,12,,,,,,,,,,,2.00E-67,ruditapes_c29908,,,,,,, comp133765_c0_seq3,2438,39.2945,0.57065234,130,37,,7.00E-176,P41823,Synaptotagmin-1 (Synaptotagmin I) (p65),Synaptotagmin-1 (Synaptotagmin I) (p65),GO:0000149; GO:0005509; GO:0030054; GO:0030285; GO:0045955; GO:0016079; GO:0005215,SNARE binding; calcium ion binding; cell junction; integral to synaptic vesicle membrane; negative regulation of calcium ion-dependent exocytosis; synaptic vesicle exocytosis; transporter activity,PF00168;,4.00E-134,CHOYP_SY65.1.1,4.00E-24,ruditapes_c25870,,,,,SY65_APLCA,Aplysia californica (California sea hare),negative regulation of calcium ion-dependent exocytosis [GO:0045955]; synaptic vesicle exocytosis [GO:0016079] comp133766_c0_seq2,1299,38.4142,0.33420117,329,1087,,1.00E-28,Q08D01,Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29),Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29),GO:0016592; GO:0006355; GO:0006351,"mediator complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11568;,,,,,,,,,MED29_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133769_c0_seq2,893,39.0817,0.3945283,74,105,,,,,,,,,,,1.00E-13,ruditapes_c26205,,,,,,, comp133775_c1_seq5,486,44.0329,0.42775763,29,35,,3.00E-46,O88693,Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase),Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase),GO:0000139; GO:0008120; GO:0016021; GO:0006665,Golgi membrane; ceramide glucosyltransferase activity; integral to membrane; sphingolipid metabolic process,PF13506;,,,,,,,,,CEGT_MOUSE,Mus musculus (Mouse),glucosylceramide biosynthetic process [GO:0006679]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp133777_c3_seq1,492,43.4959,0.54410231,30,71,,2.00E-09,Q6E2N3,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TRI33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp133779_c1_seq2,359,42.0613,0.18954166,4,0,,2.00E-10,Q12280,Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1),Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1),GO:0005099; GO:0007015; GO:0000142; GO:0000920; GO:0032320; GO:0006970; GO:0007264,Ras GTPase activator activity; actin filament organization; cellular bud neck contractile ring; cytokinetic cell separation; positive regulation of Ras GTPase activity; response to osmotic stress; small GTPase mediated signal transduction,PF00307;PF00612;PF00616;PF03836;,,,,,,,,,IQG1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin filament organization [GO:0007015]; cell cycle [GO:0007049]; cell separation after cytokinesis [GO:0000920]; response to osmotic stress [GO:0006970]; small GTPase mediated signal transduction [GO:0007264] comp133779_c3_seq1,738,41.3279,0.77166866,39,56,,4.00E-35,O00899,Ras GTPase-activating-like protein gapA (IQGAP-related protein gapA),Ras GTPase-activating-like protein gapA (IQGAP-related protein gapA),GO:0005099; GO:0005938; GO:0007049; GO:0051301; GO:0032154; GO:0005829; GO:0030175; GO:0006972; GO:0032320; GO:0051259; GO:0032956; GO:0006979; GO:0019953; GO:0007264,Ras GTPase activator activity; cell cortex; cell cycle; cell division; cleavage furrow; cytosol; filopodium; hyperosmotic response; positive regulation of Ras GTPase activity; protein oligomerization; regulation of actin cytoskeleton organization; response to oxidative stress; sexual reproduction; small GTPase mediated signal transduction,PF00616;PF03836;,4.00E-64,CHOYP_IQGA1.1.1,,,,,,,GAPA_DICDI,Dictyostelium discoideum (Slime mold),cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; negative regulation of actin filament polymerization [GO:0030837]; protein oligomerization [GO:0051259]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of myosin II filament assembly [GO:0043520]; response to oxidative stress [GO:0006979]; sexual reproduction [GO:0019953]; small GTPase mediated signal transduction [GO:0007264] comp133779_c4_seq1,1416,43.4322,0.51304522,35,137,,2.00E-139,P46940,Ras GTPase-activating-like protein IQGAP1 (p195),Ras GTPase-activating-like protein IQGAP1 (p195),GO:0005096; GO:0005095; GO:0005099; GO:0005884; GO:0005509; GO:0005516; GO:0031252; GO:0071277; GO:0005737; GO:0006112; GO:0072015; GO:0016328; GO:0005874; GO:0030496; GO:0035305; GO:0043005; GO:0005634; GO:0005886; GO:0032320; GO:0045860; GO:0001817; GO:0050796; GO:0030529; GO:0007165; GO:0036057; GO:0007264; GO:0044281,GTPase activator activity; GTPase inhibitor activity; Ras GTPase activator activity; actin filament; calcium ion binding; calmodulin binding; cell leading edge; cellular response to calcium ion; cytoplasm; energy reserve metabolic process; glomerular visceral epithelial cell development; lateral plasma membrane; microtubule; midbody; negative regulation of dephosphorylation; neuron projection; nucleus; plasma membrane; positive regulation of Ras GTPase activity; positive regulation of protein kinase activity; regulation of cytokine production; regulation of insulin secretion; ribonucleoprotein complex; signal transduction; slit diaphragm; small GTPase mediated signal transduction; small molecule metabolic process,PF00307;PF00612;PF00616;PF03836;,,,,,,,,,IQGA1_HUMAN,Homo sapiens (Human),cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glomerular visceral epithelial cell development [GO:0072015]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein kinase activity [GO:0045860]; regulation of cytokine production [GO:0001817]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] comp133779_c4_seq2,447,40.9396,0.3222265,5,3,,7.00E-07,Q55AR6,Neurofibromin-A (DdNF1),Neurofibromin-A (DdNF1),GO:0005099; GO:0005737; GO:0031235; GO:0046580; GO:0030833; GO:0050920; GO:0051896; GO:0007165,Ras GTPase activator activity; cytoplasm; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; regulation of actin filament polymerization; regulation of chemotaxis; regulation of protein kinase B signaling cascade; signal transduction,PF13716;PF00616;,9.00E-38,CHOYP_IQGA1.1.1,,,,,,,NFAA_DICDI,Dictyostelium discoideum (Slime mold),negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; regulation of chemotaxis [GO:0050920]; regulation of protein kinase B signaling [GO:0051896]; regulation of Ras protein signal transduction [GO:0046578]; signal transduction [GO:0007165] comp133780_c0_seq1,819,34.6764,0.28489223,820,733,,3.00E-15,Q2NKU0,Centromere protein X (CENP-X) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Stimulated by retinoic acid gene 13 protein homolog),Centromere protein X (CENP-X) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Stimulated by retinoic acid gene 13 protein homolog),GO:0006281; GO:0071821; GO:0043240; GO:0051301; GO:0000777; GO:0003690; GO:0051382; GO:0007067; GO:0031297; GO:0000712,DNA repair; FANCM-MHF complex; Fanconi anaemia nuclear complex; cell division; condensed chromosome kinetochore; double-stranded DNA binding; kinetochore assembly; mitosis; replication fork processing; resolution of meiotic recombination intermediates,PF09415;,,,,,,,,,CENPX_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; DNA repair [GO:0006281]; kinetochore assembly [GO:0051382]; mitotic nuclear division [GO:0007067]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp133782_c1_seq1,1108,41.065,0.49288929,348,4004,,4.00E-121,Q1L8L9,"Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)","Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)",GO:0005524; GO:0004017; GO:0002521; GO:0005758,ATP binding; adenylate kinase activity; leukocyte differentiation; mitochondrial intermembrane space,PF05191;,7.00E-76,CHOYP_BRAFLDRAFT_115743.1.1,8.00E-35,ruditapes2_c310,,,,,KAD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; leukocyte differentiation [GO:0002521] comp133785_c2_seq1,212,37.2642,0.43470355,149,554,,,,,,,,,,,6.00E-21,ruditapes_c6570,,,,,,, comp133785_c2_seq2,1190,43.5294,0.50180606,31,699,,6.00E-79,Q5RF73,Transmembrane protein 19,Transmembrane protein 19,GO:0016021,integral to membrane,PF01940;,4.00E-16,CHOYP_TMM19.1.1,,,,,,,TMM19_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp133787_c0_seq5,516,37.9845,0.10806897,63,126,,,,,,,,,,,3.00E-24,ruditapes_c19336,,,,,,, comp133789_c1_seq1,1414,36.0679,0.89666356,175,191,,9.00E-11,Q1GC56,"Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)","Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)",GO:0009234; GO:0008168; GO:0006744,menaquinone biosynthetic process; methyltransferase activity; ubiquinone biosynthetic process,PF01209;,,,,,,,,,UBIE_SILST,Ruegeria sp. (strain TM1040) (Silicibacter sp.),aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744] comp133798_c0_seq1,1242,39.7746,0.91833779,81,1594,,2.00E-40,Q9D939,Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-),Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-),GO:0005764; GO:0008146,lysosome; sulfotransferase activity,PF00685;,,,,,,,,,ST1C2_MOUSE,Mus musculus (Mouse),sulfation [GO:0051923] comp133800_c0_seq3,1477,44.1435,0.50274507,0,0,,6.00E-88,A7MB28,Protein NDRG3 (N-myc downstream-regulated gene 3 protein),Protein NDRG3 (N-myc downstream-regulated gene 3 protein),GO:0005737,cytoplasm,PF03096;,8.00E-77,CHOYP_LOC413005.1.1,,,,,,,NDRG3_BOVIN,Bos taurus (Bovine),signal transduction [GO:0007165] comp133800_c0_seq4,1076,44.7955,0.43076291,0,0,,1.00E-70,A7MB28,Protein NDRG3 (N-myc downstream-regulated gene 3 protein),Protein NDRG3 (N-myc downstream-regulated gene 3 protein),GO:0005737,cytoplasm,PF03096;,1.00E-54,CHOYP_LOC413005.1.1,,,,,,,NDRG3_BOVIN,Bos taurus (Bovine),signal transduction [GO:0007165] comp133802_c0_seq1,499,44.6894,0.69546998,0,0,,5.00E-16,Q8GB17,Carnitinyl-CoA dehydratase (EC 4.2.1.-) (Crotonobetainyl-CoA hydratase),Carnitinyl-CoA dehydratase (EC 4.2.1.149) (Crotonobetainyl-CoA hydratase),GO:0009437; GO:0016836,carnitine metabolic process; hydro-lyase activity,PF00378;,,,,,,,,,CAID_PROSL,Proteus sp. (strain LE138),carnitine metabolic process [GO:0009437] comp133802_c0_seq2,499,45.491,0.67989395,13,25,,5.00E-22,A4YI89,3-hydroxypropionyl-coenzyme A dehydratase (3-hydroxypropionyl-CoA dehydratase) (EC 4.2.1.116),3-hydroxypropionyl-coenzyme A dehydratase (3-hydroxypropionyl-CoA dehydratase) (EC 4.2.1.116),GO:0043956; GO:0006631,3-hydroxypropionyl-CoA dehydratase activity; fatty acid metabolic process,PF00378;,,,,,,,,,HPCD_METS5,Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2),fatty acid metabolic process [GO:0006631] comp133802_c0_seq4,652,37.8834,0.3503697,4,60,,,,,,,,,6.00E-11,CHOYP_LOC100556648.1.1,,,,,,,,, comp133803_c0_seq1,850,42.5882,0.52361248,16,195,,1.00E-80,Q08623,Pseudouridine-5'-monophosphatase (5'-PsiMPase) (EC 3.1.3.n6) (Haloacid dehalogenase-like hydrolase domain-containing protein 1) (Haloacid dehalogenase-like hydrolase domain-containing protein 1A) (Protein GS1),Pseudouridine-5'-phosphatase (EC 3.1.3.96) (Haloacid dehalogenase-like hydrolase domain-containing protein 1) (Haloacid dehalogenase-like hydrolase domain-containing protein 1A) (Protein GS1) (Pseudouridine-5'-monophosphatase) (5'-PsiMPase),GO:0016311; GO:0046872; GO:0009117; GO:0016791,dephosphorylation; metal ion binding; nucleotide metabolic process; phosphatase activity,PF13419;,2.00E-30,CHOYP_LOC100027252.1.1,,,,,,,HDHD1_HUMAN,Homo sapiens (Human),nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside salvage [GO:0043097] comp133811_c0_seq1,2479,49.052,0.5737216,1,6,,0,Q86YT6,E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (Zinc finger ZZ type with ankyrin repeat domain protein 2),E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (Zinc finger ZZ type with ankyrin repeat domain protein 2),GO:0007219; GO:0001568; GO:0005813; GO:0031410; GO:0005829; GO:0001947; GO:0001701; GO:0045665; GO:0001841; GO:0031965; GO:0005886; GO:0045807; GO:0001756; GO:0004842; GO:0008270,Notch signaling pathway; blood vessel development; centrosome; cytoplasmic vesicle; cytosol; heart looping; in utero embryonic development; negative regulation of neuron differentiation; neural tube formation; nuclear membrane; plasma membrane; positive regulation of endocytosis; somitogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,0,CHOYP_MIB1.3.4,,,,,,,MIB1_HUMAN,Homo sapiens (Human),blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756] comp133811_c0_seq2,1642,48.5993,0.56384433,7,0,,2.00E-103,Q96AX9,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1),GO:0007219; GO:0005768; GO:0043123; GO:0004871; GO:0004842; GO:0008270,Notch signaling pathway; endosome; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,0,CHOYP_MIB1.3.4,,,,,,,MIB2_HUMAN,Homo sapiens (Human),Notch signaling pathway [GO:0007219]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein polyubiquitination [GO:0000209] comp133811_c0_seq3,2131,49.3196,0.56359056,16,7,,6.00E-17,Q25338,Delta-latroinsectotoxin-Lt1a (Delta-LIT-Lt1a) (Delta-latroinsectotoxin) (Delta-LIT),Delta-latroinsectotoxin-Lt1a (Delta-LIT-Lt1a) (Delta-latroinsectotoxin) (Delta-LIT),GO:0006887; GO:0016021; GO:0072556,exocytosis; integral to membrane; other organism presynaptic membrane,PF12796;PF15658;,,,,,,,,,LITD_LATTR,Latrodectus tredecimguttatus (Mediterranean black widow spider) (Latrodectus mactans tredecimguttatus),exocytosis [GO:0006887] comp133811_c0_seq4,549,46.4481,0.68681547,0,0,,6.00E-13,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp133811_c0_seq5,477,46.7505,0.35285588,16,37,,1.00E-06,Q13489,Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (IAP-1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1),Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1),GO:0038061; GO:0035666; GO:0006915; GO:0007166; GO:0005829; GO:0045087; GO:0070266; GO:0043066; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0043123; GO:0039535; GO:2000116; GO:0050727; GO:0060544; GO:0070424; GO:0034121; GO:0034138; GO:0034142; GO:0004842; GO:0008270,NIK/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; apoptotic process; cell surface receptor signaling pathway; cytosol; innate immune response; necroptosis; negative regulation of apoptotic process; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of RIG-I signaling pathway; regulation of cysteine-type endopeptidase activity; regulation of inflammatory response; regulation of necroptosis; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,BIRC3_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; protein heterooligomerization [GO:0051291]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; spermatogenesis [GO:0007283]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp133811_c0_seq6,677,49.0399,0.66432138,0,0,,1.00E-10,Q6NSI1,Putative ankyrin repeat domain-containing protein 26-like protein,Putative ankyrin repeat domain-containing protein 26-like protein,,,PF12796;,,,,,,,,,AR26L_HUMAN,Homo sapiens (Human), comp133811_c0_seq8,891,49.2705,0.64976772,2,0,,4.00E-22,Q54HW1,26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),,,PF12796;,,,,,,,,,PSD10_DICDI,Dictyostelium discoideum (Slime mold), comp133811_c1_seq1,890,46.0674,0.57278644,52,17,,4.00E-14,Q8IWR0,Zinc finger CCCH domain-containing protein 7A,Zinc finger CCCH domain-containing protein 7A,GO:0046872; GO:0005634,metal ion binding; nucleus,PF00642;,,,,,,,,,Z3H7A_HUMAN,Homo sapiens (Human), comp133812_c0_seq3,557,39.4973,0.27726797,0,14,,9.00E-21,O45685,Protein MEF2BNB homolog,Protein MEF2BNB homolog,,,PF10167;,1.00E-62,CHOYP_AGAP_AGAP008600.1.1,,,,,,,MF2NB_CAEEL,Caenorhabditis elegans, comp133812_c0_seq4,732,40.9836,0.26066905,13,13,,9.00E-29,Q8IR45,Protein MEF2BNB homolog,Protein MEF2BNB homolog,,,PF10167;,,,,,,,,,MF2NB_DROME,Drosophila melanogaster (Fruit fly), comp133816_c0_seq1,2253,44.7403,0.47231819,103,144,,3.00E-24,P23880,Serine/threonine-protein phosphatase PP1-2 (EC 3.1.3.16) (Suppressor protein SDS21),Serine/threonine-protein phosphatase PP1-2 (EC 3.1.3.16) (Suppressor protein SDS21),GO:0051301; GO:0046872; GO:0000226; GO:0007067; GO:0005730; GO:0004721; GO:0000164; GO:0006364,cell division; metal ion binding; microtubule cytoskeleton organization; mitosis; nucleolus; phosphoprotein phosphatase activity; protein phosphatase type 1 complex; rRNA processing,PF00149;PF16891;,0,CHOYP_ISCW_ISCW005791.1.1,,,,,,,PP12_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of establishment of cell polarity regulating cell shape [GO:2000784]; protein dephosphorylation [GO:0006470] comp133819_c0_seq1,1035,41.1594,0.75521951,61,323,,4.00E-10,Q4JWV0,Malate dehydrogenase (EC 1.1.1.37),Malate dehydrogenase (EC 1.1.1.37),GO:0030060; GO:0044262; GO:0006108; GO:0006099,L-malate dehydrogenase activity; cellular carbohydrate metabolic process; malate metabolic process; tricarboxylic acid cycle,PF02866;PF00056;,,,,,,,,,MDH_CORJK,Corynebacterium jeikeium (strain K411),carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] comp133820_c0_seq4,828,33.5749,0.51619004,290,1228,,,,,,,,,,,9.00E-14,ruditapes_c5455,,,,,,, comp133822_c0_seq3,729,43.0727,0.36980819,41,115,,6.00E-23,Q9UGU0,Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein),Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein),GO:0003677; GO:0005634; GO:0006355; GO:0003713; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; zinc ion binding",,6.00E-11,CHOYP_LOC591426.1.1,,,,,,,TCF20_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133823_c0_seq1,2448,37.8676,0.68432683,5,19,,5.00E-25,Q96BA8,Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1],Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1],GO:0001077; GO:0003682; GO:0005789; GO:0016021; GO:0005634; GO:0030500; GO:0006986; GO:0043565,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chromatin binding; endoplasmic reticulum membrane; integral to membrane; nucleus; regulation of bone mineralization; response to unfolded protein; sequence-specific DNA binding,PF00170;,,,,,,,,,CR3L1_HUMAN,Homo sapiens (Human),endoplasmic reticulum unfolded protein response [GO:0030968]; extracellular matrix constituent secretion [GO:0070278]; multicellular organism development [GO:0007275]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; osteoblast differentiation [GO:0001649]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440] comp133823_c0_seq2,2448,37.7042,0.68995645,0,0,,2.00E-27,A2VD01,Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2],Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2],GO:0002062; GO:0005783; GO:0005789; GO:0016021; GO:0005634; GO:0034976; GO:0006986; GO:0043565; GO:0003700; GO:0044212; GO:0006351,"chondrocyte differentiation; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nucleus; response to endoplasmic reticulum stress; response to unfolded protein; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00170;,3.00E-66,CHOYP_BRAFLDRAFT_203393.1.2,,,,,,,CR3L2_XENLA,Xenopus laevis (African clawed frog),"cartilage development [GO:0051216]; chondrocyte differentiation [GO:0002062]; endoplasmic reticulum unfolded protein response [GO:0030968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]" comp133823_c0_seq3,461,46.8547,0.89354267,16,60,,,,,,,,,5.00E-16,CHOYP_BRAFLDRAFT_203393.1.2,,,,,,,,, comp133824_c0_seq1,1783,31.2956,0.55007276,3191,705,,9.00E-20,Q5BN46,UPF0691 protein C9orf116 (p53-induced expression in RB-null cells protein 1) (Pierce1),UPF0691 protein C9orf116 (p53-induced expression in RB-null cells protein 1) (Pierce1),,,,2.00E-40,CHOYP_LOC100378844.4.4,5.00E-27,ruditapes2_c1976,,,,,CI116_HUMAN,Homo sapiens (Human), comp133826_c0_seq1,1651,35.9782,0.88026788,912,898,,2.00E-14,P42322,Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit),Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CANB1_NAEGR,Naegleria gruberi (Amoeba), comp133830_c0_seq1,1186,41.3997,0.39639367,66,61,,2.00E-09,P29139,Intracellular serine protease (EC 3.4.21.-),Intracellular serine protease (EC 3.4.21.-),GO:0006508; GO:0004252,proteolysis; serine-type endopeptidase activity,PF00082;,,,,,,,,,ISP_PAEPO,Paenibacillus polymyxa (Bacillus polymyxa), comp133830_c2_seq1,343,46.0641,0.45137336,23,8,,4.00E-06,O31788,Serine protease AprX (EC 3.4.21.-),Serine protease AprX (EC 3.4.21.-),GO:0005737; GO:0006508; GO:0004252,cytoplasm; proteolysis; serine-type endopeptidase activity,PF00082;,,,,,,,,,APRX_BACSU,Bacillus subtilis (strain 168), comp133830_c2_seq2,1475,44.6102,0.36834533,34,33,,0,Q14703,Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1),Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1),GO:0000139; GO:0005795; GO:0006987; GO:0044267; GO:0008203; GO:0005788; GO:0005789; GO:0016021; GO:0006629; GO:0006508; GO:0042990; GO:0004252; GO:0044281,Golgi membrane; Golgi stack; activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; cholesterol metabolic process; endoplasmic reticulum lumen; endoplasmic reticulum membrane; integral to membrane; lipid metabolic process; proteolysis; regulation of transcription factor import into nucleus; serine-type endopeptidase activity; small molecule metabolic process,PF00082;,0,CHOYP_MBTP1.1.1,6.00E-101,ruditapes_c23317,,,,,MBTP1_HUMAN,Homo sapiens (Human),ATF6-mediated unfolded protein response [GO:0036500]; cholesterol metabolic process [GO:0008203]; lysosome organization [GO:0007040]; membrane protein intracellular domain proteolysis [GO:0031293]; proteolysis [GO:0006508]; regulation of transcription factor import into nucleus [GO:0042990]; response to endoplasmic reticulum stress [GO:0034976] comp133830_c2_seq3,767,41.5906,0.36329295,0,0,,,,,,,,,2.00E-12,CHOYP_BRAFLDRAFT_114866.4.5,,,,,,,,, comp133831_c0_seq1,1319,46.4746,0.90950249,21,5673,female>male,1.00E-77,Q9PTU6,Poly(U)-specific endoribonuclease (EC 3.1.-.-) (Pancreatic protein with two somatomedin-B domains) (Protein endoU) (Uridylate-specific endoribonuclease),Poly(U)-specific endoribonuclease (EC 3.1.-.-) (Pancreatic protein with two somatomedin-B domains) (Protein endoU) (Uridylate-specific endoribonuclease),GO:0003723; GO:0004521; GO:0005576; GO:0006955; GO:0046872; GO:0030247; GO:0005044,RNA binding; endoribonuclease activity; extracellular region; immune response; metal ion binding; polysaccharide binding; scavenger receptor activity,PF01033;PF09412;,,,3.00E-34,ruditapes_c9955,,,,,ENDOU_PAROL,Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus),immune response [GO:0006955] comp133837_c0_seq2,1481,39.2302,0.6051307,16,96,,6.00E-32,Q8R344,Coiled-coil domain-containing protein 12,Coiled-coil domain-containing protein 12,,,PF08315;,9.00E-32,CHOYP_AAEL_AAEL009922.1.1,,,,,,,CCD12_MOUSE,Mus musculus (Mouse), comp133839_c0_seq1,1546,39.5213,0.38706992,439,1366,,6.00E-158,Q8VI84,Nucleolar complex protein 3 homolog (NOC3 protein homolog) (Factor for adipocyte differentiation 24) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein),Nucleolar complex protein 3 homolog (NOC3 protein homolog) (Factor for adipocyte differentiation 24) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein),GO:0045444; GO:0016607; GO:0005730,fat cell differentiation; nuclear speck; nucleolus,PF03914;PF07540;,4.00E-36,CHOYP_NOC3L.1.1,,,,,,,NOC3L_MOUSE,Mus musculus (Mouse),fat cell differentiation [GO:0045444] comp133841_c0_seq1,648,41.6667,0.39171561,1,4,,1.00E-14,Q55FT4,Probable serine/threonine-protein kinase tsuA (EC 2.7.11.1) (Tsunami),Probable serine/threonine-protein kinase tsuA (EC 2.7.11.1) (Tsunami),GO:0005524; GO:0043327; GO:0043326; GO:0005881; GO:0030010; GO:0030837; GO:0004674; GO:0060176; GO:0031272,ATP binding; chemotaxis to cAMP; chemotaxis to folate; cytoplasmic microtubule; establishment of cell polarity; negative regulation of actin filament polymerization; protein serine/threonine kinase activity; regulation of aggregation involved in sorocarp development; regulation of pseudopodium assembly,PF00069;,,,,,,,,,TSUA_DICDI,Dictyostelium discoideum (Slime mold),chemotaxis to cAMP [GO:0043327]; chemotaxis to folate [GO:0043326]; establishment of cell polarity [GO:0030010]; negative regulation of actin filament polymerization [GO:0030837]; protein phosphorylation [GO:0006468]; regulation of aggregation involved in sorocarp development [GO:0060176]; regulation of pseudopodium assembly [GO:0031272] comp133841_c0_seq2,1991,38.222,0.31654446,86,66,,1.00E-30,Q69ZM6,Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog),Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog),GO:0005524; GO:0007420; GO:0042384; GO:0005737; GO:0003351; GO:0046872; GO:0005634; GO:0007228; GO:0045880; GO:0009791; GO:0004674; GO:0008134,ATP binding; brain development; cilium assembly; cytoplasm; epithelial cilium movement; metal ion binding; nucleus; positive regulation of hh target transcription factor activity; positive regulation of smoothened signaling pathway; post-embryonic development; protein serine/threonine kinase activity; transcription factor binding,PF00069;,,,,,,,,,STK36_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090] comp133849_c0_seq3,2067,37.881,0.51583948,0,0,,1.00E-56,Q8CDJ3,Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L),Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L),GO:0005776; GO:0000045; GO:0006914; GO:0005789; GO:0010508; GO:0034045,autophagic vacuole; autophagic vacuole assembly; autophagy; endoplasmic reticulum membrane; positive regulation of autophagy; pre-autophagosomal structure membrane,PF10186;,,,,,,,,,BAKOR_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cellular response to glucose starvation [GO:0042149]; cellular response to starvation [GO:0009267]; endosome to lysosome transport [GO:0008333]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of autophagy [GO:0010508]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of protein phosphorylation [GO:0001932]; regulation of triglyceride metabolic process [GO:0090207] comp133857_c0_seq1,2151,38.1218,0.58890171,1276,532,,5.00E-30,Q66KD0,BTB/POZ domain-containing protein 17,BTB/POZ domain-containing protein 17,GO:0005576,extracellular region,PF07707;PF00651;,,,,,,,,,BTBDH_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp133860_c0_seq1,625,41.92,0.4018451,0,7,,,,,,,,,3.00E-21,CHOYP_BRAFLDRAFT_261932.1.1,,,,,,,,, comp133860_c0_seq2,644,42.0807,0.42322937,0,50,,2.00E-46,Q9Y5Z4,Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL),Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL),GO:0005737; GO:0005739,cytoplasm; mitochondrion,PF04832;,,,,,,,,,HEBP2_HUMAN,Homo sapiens (Human),negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] comp133864_c0_seq1,328,35.6707,0.384574,0,0,,5.00E-14,O35114,Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2),Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2),GO:0007155; GO:0016021; GO:0043202; GO:0005765; GO:0006622; GO:0004872,cell adhesion; integral to membrane; lysosomal lumen; lysosomal membrane; protein targeting to lysosome; receptor activity,PF01130;,,,,,,,,,SCRB2_MOUSE,Mus musculus (Mouse),protein targeting to lysosome [GO:0006622] comp133864_c0_seq11,904,38.4956,0.57219464,0,0,,1.00E-57,Q14108,Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36),Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36),GO:0007155; GO:0005887; GO:0043202; GO:0005765; GO:0006622; GO:0004872,cell adhesion; integral to plasma membrane; lysosomal lumen; lysosomal membrane; protein targeting to lysosome; receptor activity,PF01130;,,,,,,,,,SCRB2_HUMAN,Homo sapiens (Human),protein targeting to lysosome [GO:0006622] comp133864_c0_seq9,831,45.006,0.54779228,119,210,,2.00E-50,Q08857,Platelet glycoprotein 4 (Glycoprotein IIIb) (GPIIIB) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (GPIV) (CD antigen CD36),Platelet glycoprotein 4 (Glycoprotein IIIb) (GPIIIB) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (GPIV) (CD antigen CD36),GO:0005794; GO:0043277; GO:0019934; GO:0007155; GO:0007166; GO:0071221; GO:0071447; GO:0071222; GO:0071223; GO:0030301; GO:0050830; GO:0009897; GO:0008035; GO:0016021; GO:0008289; GO:0019915; GO:0042953; GO:0070892; GO:0044539; GO:0030169; GO:0034383; GO:0055096; GO:0005041; GO:0045121; GO:0044130; GO:0042992; GO:0000122; GO:0007263; GO:0006910; GO:0015911; GO:0043123; GO:0043410; GO:0030194; GO:2000334; GO:0001954; GO:0010886; GO:0032735; GO:0032755; GO:0060907; GO:0010744; GO:0050731; GO:0060100; GO:2000379; GO:0032760; GO:2000121; GO:0043619; GO:0035634,"Golgi apparatus; apoptotic cell clearance; cGMP-mediated signaling; cell adhesion; cell surface receptor signaling pathway; cellular response to bacterial lipopeptide; cellular response to hydroperoxide; cellular response to lipopolysaccharide; cellular response to lipoteichoic acid; cholesterol transport; defense response to Gram-positive bacterium; external side of plasma membrane; high-density lipoprotein particle binding; integral to membrane; lipid binding; lipid storage; lipoprotein transport; lipoteichoic acid receptor activity; long-chain fatty acid import; low-density lipoprotein particle binding; low-density lipoprotein particle clearance; low-density lipoprotein particle mediated signaling; low-density lipoprotein receptor activity; membrane raft; negative regulation of growth of symbiont in host; negative regulation of transcription factor import into nucleus; negative regulation of transcription from RNA polymerase II promoter; nitric oxide mediated signal transduction; phagocytosis, recognition; plasma membrane long-chain fatty acid transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAPK cascade; positive regulation of blood coagulation; positive regulation of blood microparticle formation; positive regulation of cell-matrix adhesion; positive regulation of cholesterol storage; positive regulation of interleukin-12 production; positive regulation of interleukin-6 production; positive regulation of macrophage cytokine production; positive regulation of macrophage derived foam cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phagocytosis, engulfment; positive regulation of reactive oxygen species metabolic process; positive regulation of tumor necrosis factor production; regulation of removal of superoxide radicals; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; response to stilbenoid",PF01130;,,,,,,,,,CD36_MOUSE,Mus musculus (Mouse),"amyloid fibril formation [GO:1990000]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to bacterial lipopeptide [GO:0071221]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; cellular response to hydroperoxide [GO:0071447]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cGMP-mediated signaling [GO:0019934]; cholesterol import [GO:0070508]; cholesterol transport [GO:0030301]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; interleukin-1 beta secretion [GO:0050702]; intestinal absorption [GO:0050892]; intestinal cholesterol absorption [GO:0030299]; lipid storage [GO:0019915]; lipoprotein transport [GO:0042953]; long-chain fatty acid import [GO:0044539]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of gene expression [GO:0010629]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nitric oxide mediated signal transduction [GO:0007263]; phagocytosis, recognition [GO:0006910]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of tumor necrosis factor production [GO:0032760]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of energy homeostasis [GO:2000505]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to fatty acid [GO:0070542]; response to linoleic acid [GO:0070543]; response to lipid [GO:0033993]; response to stilbenoid [GO:0035634]; sensory perception of taste [GO:0050909]; triglyceride transport [GO:0034197]" comp133866_c0_seq3,940,32.6596,0.80324461,92,397,,2.00E-14,Q3U898,Myeloma-overexpressed gene 2 protein homolog,Myeloma-overexpressed gene 2 protein homolog,,,PF15004;,6.00E-38,CHOYP_MYEOV2.1.1,1.00E-51,ruditapes_c14081,,,,,MYOV2_MOUSE,Mus musculus (Mouse), comp133868_c0_seq1,1417,37.9675,0.67466204,31,711,,2.00E-89,Q502L2,"Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5)","Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5)",GO:0016021; GO:0005741; GO:0004721,integral to membrane; mitochondrial outer membrane; phosphoprotein phosphatase activity,PF00300;,1.00E-60,CHOYP_LOC588383.1.1,,,,,,,PGAM5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),programmed cell death [GO:0012501] comp133871_c0_seq2,633,33.8073,0.49947604,44,401,,3.00E-26,Q6ZN57,Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751),Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZFP2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133875_c0_seq1,1648,39.3204,0.91111949,0,0,,6.00E-41,Q99JL1,Sperm flagellar protein 1,Sperm flagellar protein 1,GO:0035085; GO:0005856,cilium axoneme; cytoskeleton,PF06294;,8.00E-39,CHOYP_LOC100492226.2.2,,,,,,,SPEF1_MOUSE,Mus musculus (Mouse), comp133875_c0_seq5,1498,39.3858,0.87848219,0,0,,6.00E-32,Q9Y4P9,Sperm flagellar protein 1,Sperm flagellar protein 1,GO:0035085; GO:0005856,cilium axoneme; cytoskeleton,PF06294;,8.00E-39,CHOYP_LOC100492226.2.2,,,,,,,SPEF1_HUMAN,Homo sapiens (Human), comp133875_c0_seq9,1411,38.696,0.89055332,0,0,,1.00E-43,Q99JL1,Sperm flagellar protein 1,Sperm flagellar protein 1,GO:0035085; GO:0005856,cilium axoneme; cytoskeleton,PF06294;,1.00E-36,CHOYP_LOC100371058.2.3,,,,,,,SPEF1_MOUSE,Mus musculus (Mouse), comp133876_c0_seq1,1718,43.1315,0.43887883,10,85,,6.00E-46,P33269,Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1),Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1),GO:0005789; GO:0020037; GO:0005506; GO:0005811; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; lipid particle; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP4D1_DROME,Drosophila melanogaster (Fruit fly), comp133876_c0_seq2,1710,43.0409,0.44241298,14,48,,2.00E-39,O48786,Cytochrome P450 734A1 (EC 1.14.-.-) (Protein PHYB ACTIVATION-TAGGED SUPPRESSOR 1),Cytochrome P450 734A1 (EC 1.14.-.-) (Protein PHYB ACTIVATION-TAGGED SUPPRESSOR 1),GO:0010268; GO:0016131; GO:0020037; GO:0016021; GO:0005506; GO:0016705; GO:0040008; GO:0009741; GO:0009416; GO:0008395,"brassinosteroid homeostasis; brassinosteroid metabolic process; heme binding; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; regulation of growth; response to brassinosteroid stimulus; response to light stimulus; steroid hydroxylase activity",PF00067;,,,,,,,,,C734A_ARATH,Arabidopsis thaliana (Mouse-ear cress),brassinosteroid homeostasis [GO:0010268]; brassinosteroid metabolic process [GO:0016131]; regulation of growth [GO:0040008]; response to brassinosteroid [GO:0009741] comp133876_c0_seq3,938,43.8166,0.40425781,0,0,,2.00E-11,B9X287,Cytochrome P450 734A6 (EC 1.14.-.-),Cytochrome P450 734A6 (EC 1.14.-.-),GO:0010268; GO:0016131; GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705; GO:0040008,"brassinosteroid homeostasis; brassinosteroid metabolic process; heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; regulation of growth",PF00067;,,,,,,,,,C7346_ORYSJ,Oryza sativa subsp. japonica (Rice),brassinosteroid homeostasis [GO:0010268]; brassinosteroid metabolic process [GO:0016131]; regulation of growth [GO:0040008] comp133881_c0_seq1,1975,37.5696,0.72716914,10,37,,,,,,,,,1.00E-30,CHOYP_LRRF2.1.2,,,,,,,,, comp133881_c0_seq2,1697,38.0082,0.66074017,0,4,,2.00E-34,Q2T9W6,Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2),Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2),GO:0016055,Wnt receptor signaling pathway,PF09738;,1.00E-30,CHOYP_LRRF2.1.2,,,,,,,LRRF2_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; Wnt signaling pathway [GO:0016055]" comp133882_c0_seq2,2650,42.3019,0.55869701,67,155,,,,,,,,,7.00E-17,CHOYP_AKP13.5.5,,,,,,,,, comp133891_c1_seq1,1270,40.315,0.40802594,12,97,,7.00E-41,Q5BKX0,Transmembrane protein 248,Transmembrane protein 248,GO:0016021,integral to membrane,,,,,,,,,,TM248_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp133892_c0_seq1,900,37.7778,0.69651163,0,0,,3.00E-12,Q96C55,Zinc finger protein 524,Zinc finger protein 524,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZN524_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133892_c0_seq3,685,36.7883,0.44568702,9,72,,1.00E-10,Q96NG8,Zinc finger protein 582,Zinc finger protein 582,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN582_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp133894_c0_seq1,2770,40.722,1.05470602,2498,0,,3.00E-12,Q8XJL8,Probable serine/threonine-protein kinase CPE1738 (EC 2.7.11.1),Probable serine/threonine-protein kinase CPE1738 (EC 2.7.11.1),GO:0005524; GO:0008658; GO:0004674,ATP binding; penicillin binding; protein serine/threonine kinase activity,PF03793;PF00069;,,,,,,,,,PKN2_CLOPE,Clostridium perfringens (strain 13 / Type A), comp133895_c0_seq1,1120,39.1071,0.31091081,70,354,,6.00E-91,Q8WV92,MIT domain-containing protein 1,MIT domain-containing protein 1,GO:0000920; GO:0019898; GO:0043231; GO:0031902; GO:0030496; GO:0000281; GO:0006810,cytokinetic cell separation; extrinsic to membrane; intracellular membrane-bounded organelle; late endosome membrane; midbody; mitotic cytokinesis; transport,PF04212;PF16565;,,,,,,,,,MITD1_HUMAN,Homo sapiens (Human),cell separation after cytokinesis [GO:0000920]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091]; transport [GO:0006810] comp133896_c0_seq1,887,39.9098,0.82240707,538,1524,,3.00E-42,Q8K0H5,Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30),Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30),GO:0003677; GO:0006352; GO:0000082; GO:0006915; GO:0043623; GO:0009790; GO:0070365; GO:0035264; GO:0051101; GO:0006355; GO:0005669,"DNA binding; DNA-dependent transcription, initiation; G1/S transition of mitotic cell cycle; apoptotic process; cellular protein complex assembly; embryo development; hepatocyte differentiation; multicellular organism growth; regulation of DNA binding; regulation of transcription, DNA-dependent; transcription factor TFIID complex",PF03540;,,,8.00E-53,ruditapes_lrc35922,,,,,TAF10_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; DNA-templated transcription, initiation [GO:0006352]; G1/S transition of mitotic cell cycle [GO:0000082]; hepatocyte differentiation [GO:0070365]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; protein homooligomerization [GO:0051260]; regulation of DNA binding [GO:0051101]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp133896_c0_seq2,911,39.7366,0.8636374,389,1677,,3.00E-42,Q8K0H5,Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30),Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30),GO:0003677; GO:0006352; GO:0000082; GO:0006915; GO:0043623; GO:0009790; GO:0070365; GO:0035264; GO:0051101; GO:0006355; GO:0005669,"DNA binding; DNA-dependent transcription, initiation; G1/S transition of mitotic cell cycle; apoptotic process; cellular protein complex assembly; embryo development; hepatocyte differentiation; multicellular organism growth; regulation of DNA binding; regulation of transcription, DNA-dependent; transcription factor TFIID complex",PF03540;,3.00E-48,CHOYP_BRAFLDRAFT_128646.1.1,2.00E-40,ruditapes_lrc33975,,,,,TAF10_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; DNA-templated transcription, initiation [GO:0006352]; G1/S transition of mitotic cell cycle [GO:0000082]; hepatocyte differentiation [GO:0070365]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; protein homooligomerization [GO:0051260]; regulation of DNA binding [GO:0051101]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp133900_c0_seq1,1762,34.1657,0.44756085,104,886,,5.00E-68,Q9JLY0,Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4),Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4),GO:0005829; GO:0001772; GO:0035556; GO:0050868; GO:0009968; GO:0010498; GO:0016567; GO:0040008,cytosol; immunological synapse; intracellular signal transduction; negative regulation of T cell activation; negative regulation of signal transduction; proteasomal protein catabolic process; protein ubiquitination; regulation of growth,PF00017;PF07525;,7.00E-78,CHOYP_SOCS6.1.1,,,,,,,SOCS6_MOUSE,Mus musculus (Mouse),cytokine-mediated signaling pathway [GO:0019221]; intracellular signal transduction [GO:0035556]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell activation [GO:0050868]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008] comp133903_c1_seq2,915,39.6721,0.45064933,0,0,,3.00E-25,Q4G0A6,Protein FAM188B,Protein FAM188B,,,PF13898;,,,,,,,,,F188B_HUMAN,Homo sapiens (Human), comp133903_c1_seq4,891,42.8732,0.58785806,0,0,,5.00E-32,Q0VA42,Protein FAM188B,Protein FAM188B,,,PF13898;,,,,,,,,,F188B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp133903_c1_seq6,1524,41.601,0.47339402,0,0,,2.00E-66,A8MYZ0,Protein FAM188B2,Protein FAM188B2,,,PF13898;,,,,,,,,,F1882_HUMAN,Homo sapiens (Human), comp133903_c1_seq8,996,38.5542,0.41325896,0,0,,8.00E-06,Q6NX27,Protein FAM188A (Protein CARP),Protein FAM188A (Protein CARP),GO:0006915; GO:0005634,apoptotic process; nucleus,PF13898;,,,,,,,,,F188A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),apoptotic process [GO:0006915] comp133904_c0_seq1,1919,40.9588,0.31722333,84,173,,4.00E-66,Q8C9S4,Uncharacterized protein C10orf118 homolog (Oocyte-testis gene 1 protein),Coiled-coil domain-containing protein 186 (Oocyte-testis gene 1 protein),,,,3.00E-45,CHOYP_CJ118.1.1,,,,,,,CJ118_MOUSE,Mus musculus (Mouse), comp133904_c2_seq1,280,42.5,0.24577573,13,15,,,,,,,,,,,3.00E-33,ruditapes_c14820,,,,,,, comp133906_c1_seq1,1127,44.9867,0.35117241,53,85,,9.00E-120,Q9Y4E6,WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG),WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG),,,PF00400;,1.00E-136,CHOYP_PHUM_PHUM035190.1.1,,,,,,,WDR7_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244] comp133907_c0_seq2,704,43.608,0.38900758,20,65,,3.00E-25,D3ZPX4,Plexin-A3,Plexin-A3,GO:0007411; GO:0021766; GO:0016021; GO:0005622; GO:0050919; GO:0048843; GO:0005886; GO:0051495; GO:0021860; GO:0017154,axon guidance; hippocampus development; integral to membrane; intracellular; negative chemotaxis; negative regulation of axon extension involved in axon guidance; plasma membrane; positive regulation of cytoskeleton organization; pyramidal neuron development; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA3_RAT,Rattus norvegicus (Rat),branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; hippocampus development [GO:0021766]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron projection extension [GO:1990138]; positive regulation of cytoskeleton organization [GO:0051495]; pyramidal neuron development [GO:0021860]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; trigeminal nerve structural organization [GO:0021637] comp133907_c1_seq1,2109,41.394,0.57307656,75,281,,4.00E-67,P23049,Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2),Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2),GO:0005524; GO:0004715; GO:0018108,ATP binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF07714;,3.00E-14,CHOYP_LOC589012.1.1,,,,,,,SEA_AVIET,Avian erythroblastosis virus (strain S13), comp133910_c0_seq1,633,44.8657,0.98059418,52,66,,7.00E-08,P86786,Gigasin-3a (Fragment),Gigasin-3a (Fragment),GO:0016787; GO:0009166,hydrolase activity; nucleotide catabolic process,,,,3.00E-37,ruditapes2_c750,,,,,GIGA3_CRAGI,Crassostrea gigas (Pacific oyster) (Crassostrea angulata), comp133910_c0_seq3,247,47.3684,1.01462797,0,0,,,,,,,,,,,1.00E-11,ruditapes_c17871,,,,,,, comp133910_c0_seq6,774,44.9612,0.84699595,13,4,,1.00E-11,P08472,Mesenchyme-specific cell surface glycoprotein (MSP130),Mesenchyme-specific cell surface glycoprotein (MSP130),GO:0031225; GO:0016787; GO:0009166; GO:0005886,anchored to membrane; hydrolase activity; nucleotide catabolic process; plasma membrane,,,,,,,,,,M130_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp133912_c0_seq1,990,36.9697,0.39200989,67,180,,1.00E-08,O88843,Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),GO:0006977; GO:0006919; GO:0071260; GO:0005737; GO:0005634; GO:2001235,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to mechanical stimulus; cytoplasm; nucleus; positive regulation of apoptotic signaling pathway",PF00619;PF00531;,,,1.00E-32,ruditapes_c25507,,,,,CRADD_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; positive regulation of apoptotic signaling pathway [GO:2001235]" comp133913_c5_seq9,722,42.1053,0.28564585,21,77,,3.00E-76,Q0P570,Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase),Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase),GO:0005524; GO:0030544; GO:0006695; GO:0005829; GO:0004163; GO:0008299; GO:0008284; GO:0042803,ATP binding; Hsp70 protein binding; cholesterol biosynthetic process; cytosol; diphosphomevalonate decarboxylase activity; isoprenoid biosynthetic process; positive regulation of cell proliferation; protein homodimerization activity,PF00288;,4.00E-38,CHOYP_MVD1.1.1,,,,,,,MVD1_BOVIN,Bos taurus (Bovine),"cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell proliferation [GO:0008284]" comp133915_c0_seq5,718,40.6685,0.62401278,0,0,,,,,,,,,3.00E-34,CHOYP_BRAFLDRAFT_124389.1.1,,,,,,,,, comp133916_c0_seq1,1205,37.8423,0.65882398,301,1057,,1.00E-71,Q9VHN6,"39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19)","39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF01245;,,,9.00E-54,ruditapes2_c1843,,,,,RM19_DROME,Drosophila melanogaster (Fruit fly),sensory perception of pain [GO:0019233]; translation [GO:0006412] comp133917_c0_seq1,986,40.2637,0.31433153,106,556,,,,,,,,,1.00E-22,CHOYP_INO80E.1.1,,,,,,,,, comp133918_c0_seq2,2069,45.6742,0.57742158,116,232,,0,Q6UXM1,Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3),Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3),GO:0030659; GO:0016021; GO:0007275; GO:0005886,cytoplasmic vesicle membrane; integral to membrane; multicellular organismal development; plasma membrane,PF07679;PF13855;,2.00E-16,CHOYP_LRIG3.2.3,,,,,,,LRIG3_HUMAN,Homo sapiens (Human),otolith morphogenesis [GO:0032474] comp133926_c0_seq1,982,37.0672,0.84606814,59,220,,1.00E-106,Q299F9,Protein FAM50 homolog,Protein FAM50 homolog,GO:0005634,nucleus,PF04921;,6.00E-127,CHOYP_FAM50.1.1,1.00E-82,ruditapes_c10223,,,,,FAM50_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp133926_c0_seq3,294,38.4354,0.6704623,0,4,,6.00E-07,A8WXX7,Protein FAM50 homolog,Protein FAM50 homolog,GO:0005634,nucleus,PF04921;,,,,,,,,,FAM50_CAEBR,Caenorhabditis briggsae, comp133926_c0_seq4,393,36.8957,0.41093299,15,70,,5.00E-26,Q9VAY7,Protein FAM50 homolog,Protein FAM50 homolog,GO:0022008; GO:0005634,neurogenesis; nucleus,PF04921;,2.00E-45,CHOYP_FAM50.1.1,,,,,,,FAM50_DROME,Drosophila melanogaster (Fruit fly),neurogenesis [GO:0022008] comp133928_c1_seq2,1489,40.9671,0.30634287,4,29,,3.00E-68,O08795,Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH),Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH),GO:0006491; GO:0003723; GO:0005509; GO:0005783; GO:0001701; GO:0001889; GO:0010977; GO:0006807; GO:0072001,N-glycan processing; RNA binding; calcium ion binding; endoplasmic reticulum; in utero embryonic development; liver development; negative regulation of neuron projection development; nitrogen compound metabolic process; renal system development,PF13202;PF12999;PF13015;,,,,,,,,,GLU2B_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; negative regulation of neuron projection development [GO:0010977]; N-glycan processing [GO:0006491]; nitrogen compound metabolic process [GO:0006807]; protein heterooligomerization [GO:0051291]; renal system development [GO:0072001] comp133928_c1_seq6,1345,40.0743,0.2602786,5,127,,,,,,,,,4.00E-42,CHOYP_RS32.1.1,,,,,,,,, comp133934_c0_seq1,1282,43.0577,0.47169146,6,19,,2.00E-52,Q14DL3,Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44),Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44),,,PF12799;,,,,,,,,,LRIQ3_MOUSE,Mus musculus (Mouse), comp133934_c0_seq2,2883,42.3864,0.57536942,1965,81,,,,,,,,,4.00E-46,CHOYP_BRAFLDRAFT_124759.1.1,,,,,,,,, comp133943_c0_seq2,877,44.8119,0.61405043,0,0,,7.00E-09,Q5TG08,Putative uncharacterized protein LOC388900,,,,,,,,,,,,,YV009_HUMAN,, comp133944_c0_seq1,1415,38.0919,0.47062757,139,235,,6.00E-36,Q9NQM4,Protein PIH1D3 (PIH1 domain-containing protein 3) (Sarcoma antigen NY-SAR-97),Protein PIH1D3 (PIH1 domain-containing protein 3) (Sarcoma antigen NY-SAR-97),,,,5.00E-47,CHOYP_LOC756974.1.1,3.00E-86,ruditapes_c18013,,,,,PIHD3_HUMAN,Homo sapiens (Human),axonemal dynein complex assembly [GO:0070286]; sperm motility [GO:0030317] comp133945_c0_seq2,1188,32.4916,0.45514483,7,0,,4.00E-21,Q9D9W1,Protein pitchfork,Protein pitchfork,GO:0005795; GO:0048487; GO:0030030; GO:0016023; GO:0043015; GO:0005932; GO:0005634; GO:0033674; GO:0031344; GO:0005802,Golgi stack; beta-tubulin binding; cell projection organization; cytoplasmic membrane-bounded vesicle; gamma-tubulin binding; microtubule basal body; nucleus; positive regulation of kinase activity; regulation of cell projection organization; trans-Golgi network,PF07004;,,,,,,,,,PIFO_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; positive regulation of kinase activity [GO:0033674]; regulation of cell projection organization [GO:0031344] comp133945_c0_seq3,1414,33.5219,0.53176476,113,2,,5.00E-28,Q2TBS4,Protein pitchfork,Protein pitchfork,GO:0005794; GO:0030030; GO:0016023; GO:0005932; GO:0033674; GO:0031344; GO:0005802,Golgi apparatus; cell projection organization; cytoplasmic membrane-bounded vesicle; microtubule basal body; positive regulation of kinase activity; regulation of cell projection organization; trans-Golgi network,,9.00E-57,CHOYP_BRAFLDRAFT_128029.1.1,,,,,,,PIFO_BOVIN,Bos taurus (Bovine),cell projection organization [GO:0030030]; positive regulation of kinase activity [GO:0033674]; regulation of cell projection organization [GO:0031344] comp133946_c0_seq1,1212,40.5941,1.01105308,20,37,,1.00E-63,P25782,Digestive cysteine proteinase 2 (EC 3.4.22.-),Digestive cysteine proteinase 2 (EC 3.4.22.-),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF08246;PF00112;,5.00E-15,CHOYP_CTSL2.2.2,,,,,,,CYSP2_HOMAM,Homarus americanus (American lobster), comp133946_c0_seq3,1124,41.3701,1.0513241,0,5,,2.00E-60,P07711,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],GO:0002250; GO:0019886; GO:0097067; GO:0030574; GO:0004197; GO:0036021; GO:0022617; GO:0005576; GO:0042393; GO:0045087; GO:0071888; GO:0005634; GO:0006508; GO:0002224,adaptive immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; cellular response to thyroid hormone stimulus; collagen catabolic process; cysteine-type endopeptidase activity; endolysosome lumen; extracellular matrix disassembly; extracellular region; histone binding; innate immune response; macrophage apoptotic process; nucleus; proteolysis; toll-like receptor signaling pathway,PF08246;PF00112;,3.00E-17,CHOYP_LOC659226.3.3,1.00E-14,ruditapes_c5071,,,,,CATL1_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; toll-like receptor signaling pathway [GO:0002224] comp133947_c0_seq1,2464,40.7873,0.37679009,7533,1054,,1.00E-97,Q8BYM7,Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3),Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3),GO:0035085; GO:0035083; GO:0003341; GO:0005856; GO:0005730; GO:0001534,cilium axoneme; cilium axoneme assembly; cilium movement; cytoskeleton; nucleolus; radial spoke,PF04712;,0,CHOYP_LOC100376902.1.1,3.00E-94,ruditapes2_c1677,,,,,RSH4A_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; cilium movement [GO:0003341] comp133951_c0_seq1,1857,37.6952,0.63009117,6034,12824,,4.00E-84,Q5BK63,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Sperm flagella protein 3)","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Sperm flagella protein 3)",GO:0005743; GO:0005759; GO:0055114; GO:0070469,mitochondrial inner membrane; mitochondrial matrix; oxidation-reduction process; respiratory chain,PF05368;,,,,,,,,,NDUA9_RAT,Rattus norvegicus (Rat),response to glucose [GO:0009749]; ubiquinone-6 biosynthetic process [GO:1901006] comp133957_c0_seq1,1384,35.9104,0.27298723,2750,9757,,3.00E-134,P25788,Proteasome subunit alpha type-3 (EC 3.4.25.1) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8),Proteasome subunit alpha type-3 (EC 3.4.25.1) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8),GO:0006977; GO:0000082; GO:0031145; GO:0002479; GO:0006915; GO:0005829; GO:0010467; GO:0016071; GO:0019048; GO:0043066; GO:0051436; GO:0005654; GO:0051437; GO:0005839; GO:0019773; GO:0000209; GO:0006521; GO:0044281; GO:0004298; GO:0016032,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; G1/S transition of mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; apoptotic process; cytosol; gene expression; mRNA metabolic process; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; proteasome core complex; proteasome core complex, alpha-subunit complex; protein polyubiquitination; regulation of cellular amino acid metabolic process; small molecule metabolic process; threonine-type endopeptidase activity; viral process",PF00227;PF10584;,7.00E-134,CHOYP_BRAFLDRAFT_264234.2.2,0,ruditapes_c919,,,,,PSA3_HUMAN,Homo sapiens (Human),"anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of endopeptidase activity [GO:0052548]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp133961_c1_seq1,870,37.2414,0.60188962,0,0,,2.00E-11,Q94521,Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1),GO:0004059; GO:0004060; GO:0005737; GO:0048066; GO:0042420; GO:0030187; GO:0046334; GO:0045187; GO:0042429; GO:0030431,"aralkylamine N-acetyltransferase activity; arylamine N-acetyltransferase activity; cytoplasm; developmental pigmentation; dopamine catabolic process; melatonin biosynthetic process; octopamine catabolic process; regulation of circadian sleep/wake cycle, sleep; serotonin catabolic process; sleep",PF00583;,,,,,,,,,DNAT_DROME,Drosophila melanogaster (Fruit fly),"catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]" comp133962_c1_seq1,865,36.3006,0.81335491,91,789,,6.00E-40,Q4KLM5,Activator of basal transcription 1,Activator of basal transcription 1,GO:0003677; GO:0003723; GO:0005730; GO:0000166; GO:0006355; GO:0006351,"DNA binding; RNA binding; nucleolus; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,7.00E-37,CHOYP_LOC591612.1.2,,,,,,,ABT1_RAT,Rattus norvegicus (Rat),"endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; small-subunit processome assembly [GO:0034462]; spinal cord motor neuron differentiation [GO:0021522]; transcription from RNA polymerase II promoter [GO:0006366]" comp133965_c0_seq1,3021,48.0967,0.54196769,0,0,,5.00E-11,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp133965_c1_seq2,1913,45.3215,0.41370378,0,0,,1.00E-19,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp133965_c1_seq3,1571,45.4488,0.45026871,0,2,,7.00E-20,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp133966_c2_seq1,1731,35.2975,0.37144279,154,1116,,,,,,,,,,,1.00E-21,ruditapes_c15855,,,,,,, comp133968_c0_seq1,840,41.1905,0.62744256,63,465,,1.00E-69,Q6AY55,Dephospho-CoA kinase domain-containing protein,Dephospho-CoA kinase domain-containing protein,GO:0005524; GO:0015937; GO:0004140,ATP binding; coenzyme A biosynthetic process; dephospho-CoA kinase activity,PF01121;,5.00E-19,CHOYP_LOC101482309.1.1,,,,,,,DCAKD_RAT,Rattus norvegicus (Rat),coenzyme A biosynthetic process [GO:0015937] comp133979_c1_seq1,1505,40.0664,0.43189007,8,33,,9.00E-153,A7RJI7,Vacuolar fusion protein CCZ1 homolog,Vacuolar fusion protein CCZ1 homolog,,,PF08217;,2.00E-97,CHOYP_BRAFLDRAFT_113848.1.1,7.00E-18,ruditapes_c27888,,,,,CCZ1_NEMVE,Nematostella vectensis (Starlet sea anemone),vesicle-mediated transport [GO:0016192] comp133979_c1_seq2,1481,41.0533,0.41782713,0,11,,1.00E-114,Q8C1Y8,Vacuolar fusion protein CCZ1 homolog,Vacuolar fusion protein CCZ1 homolog,GO:0005765,lysosomal membrane,PF08217;,,,,,,,,,CCZ1_MOUSE,Mus musculus (Mouse),vesicle-mediated transport [GO:0016192] comp133987_c1_seq4,2224,42.2662,0.33403704,0,0,,2.00E-86,Q5ZLL7,WD repeat-containing protein 91,WD repeat-containing protein 91,,,PF12894;,9.00E-40,CHOYP_WDR91.1.1,,,,,,,WDR91_CHICK,Gallus gallus (Chicken), comp133987_c1_seq5,1028,37.4514,0.30744814,0,0,,3.00E-40,Q05B30,WD repeat-containing protein 91,WD repeat-containing protein 91,,,PF00400;,,,,,,,,,WDR91_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp133988_c0_seq1,1156,41.955,0.89959636,32,314,,1.00E-29,Q09621,Beta-lactamase domain-containing protein 2,Beta-lactamase domain-containing protein 2,GO:0016021,integral to membrane,PF00144;,,,,,,,,,LACT2_CAEEL,Caenorhabditis elegans, comp133993_c0_seq1,1280,41.4062,0.42246337,16,185,,2.00E-142,Q3T058,Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta),Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta),GO:0051716; GO:0005851; GO:0005085; GO:0042552; GO:0045947; GO:0014003; GO:0001541; GO:0003743; GO:0006413,cellular response to stimulus; eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor activity; myelination; negative regulation of translational initiation; oligodendrocyte development; ovarian follicle development; translation initiation factor activity; translational initiation,PF01008;,1.00E-91,CHOYP_BRAFLDRAFT_240825.1.1,,,,,,,EI2BD_BOVIN,Bos taurus (Bovine),cellular response to stimulus [GO:0051716]; myelination [GO:0042552]; negative regulation of translational initiation [GO:0045947]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; translational initiation [GO:0006413] comp133999_c0_seq1,602,41.5282,0.95054449,0,13,,,,,,,,,2.00E-15,CHOYP_BRAFLDRAFT_61250.3.14,,,,,,,,, comp133999_c0_seq3,504,46.0317,0.99019998,0,3,,,,,,,,,1.00E-17,CHOYP_BRAFLDRAFT_61250.11.14,,,,,,,,, comp133999_c0_seq4,360,44.4444,1.01675014,2,7,,,,,,,,,5.00E-15,CHOYP_BRAFLDRAFT_58592.1.2,,,,,,,,, comp133999_c0_seq5,1776,42.5113,0.97860744,4,46,,1.00E-35,Q9VYY4,Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15),Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C4G15_DROME,Drosophila melanogaster (Fruit fly),sensory perception of pain [GO:0019233]; steroid biosynthetic process [GO:0006694] comp133999_c0_seq6,1720,43.2558,1.00921643,23,57,,1.00E-101,P14579,Cytochrome P450 4A5 (CYPIVA5) (Lauric acid omega-hydroxylase) (EC 1.14.15.3),Cytochrome P450 4A5 (CYPIVA5) (Lauric acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.13.205),GO:0018685; GO:0052869; GO:0005789; GO:0020037; GO:0016021; GO:0005506,alkane 1-monooxygenase activity; arachidonic acid omega-hydroxylase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,2.00E-15,CHOYP_BRAFLDRAFT_61250.7.14,4.00E-15,ruditapes2_c2019,,,,,CP4A5_RABIT,Oryctolagus cuniculus (Rabbit), comp134004_c0_seq3,1478,42.9635,0.50260893,24,106,,2.00E-96,P97868,E3 ubiquitin-protein ligase RBBP6 (EC 6.3.2.-) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis),E3 ubiquitin-protein ligase RBBP6 (EC 6.3.2.-) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis),GO:0005694; GO:0005737; GO:0048568; GO:0001701; GO:0005815; GO:0035264; GO:0003676; GO:0005730; GO:0042787; GO:0061053; GO:0004842; GO:0008270,chromosome; cytoplasm; embryonic organ development; in utero embryonic development; microtubule organizing center; multicellular organism growth; nucleic acid binding; nucleolus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; somite development; ubiquitin-protein ligase activity; zinc ion binding,PF08783;PF04564;PF13696;,,,,,,,,,RBBP6_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; embryonic organ development [GO:0048568]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of DNA replication [GO:0006275]; somite development [GO:0061053] comp134005_c0_seq7,1664,40.7452,1.30314936,2765,20973,,5.00E-09,Q9R171,Cerebellin-1 (Brain protein D3) (Precerebellin) [Cleaved into: Cerebellin (CER); [des-Ser1]-cerebellin (des-Ser1-cerebellin)],Cerebellin-1 (Brain protein D3) (Precerebellin) [Cleaved into: Cerebellin (CER); [des-Ser1]-cerebellin (des-Ser1-cerebellin)],GO:0030054; GO:0005576; GO:0051965; GO:0045211; GO:0042803; GO:0009306; GO:0045202,cell junction; extracellular region; positive regulation of synapse assembly; postsynaptic membrane; protein homodimerization activity; protein secretion; synapse,PF00386;,,,,,,,,,CBLN1_MOUSE,Mus musculus (Mouse),cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306] comp134006_c0_seq1,3013,43.08,0.44689844,104,246,,0,Q64566,Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1),Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1),GO:0005524; GO:0032468; GO:0032472; GO:0000139; GO:0031532; GO:0005509; GO:0070509; GO:0016339; GO:0005388; GO:0030026; GO:0008544; GO:0016021; GO:0030145; GO:0015410; GO:0005886; GO:0043123; GO:0030141; GO:0004871; GO:0005802; GO:0030133,ATP binding; Golgi calcium ion homeostasis; Golgi calcium ion transport; Golgi membrane; actin cytoskeleton reorganization; calcium ion binding; calcium ion import; calcium-dependent cell-cell adhesion; calcium-transporting ATPase activity; cellular manganese ion homeostasis; epidermis development; integral to membrane; manganese ion binding; manganese-transporting ATPase activity; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; secretory granule; signal transducer activity; trans-Golgi network; transport vesicle,PF00689;PF00690;PF00122;,0,CHOYP_SPCA.1.1,,,,,,,AT2C1_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cellular manganese ion homeostasis [GO:0030026]; epidermis development [GO:0008544]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; manganese ion transport [GO:0006828]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp134008_c0_seq1,469,39.0192,0.39354246,5,66,,,,,,,,,1.00E-37,CHOYP_ACA1_027810.1.1,,,,,,,,, comp134010_c0_seq1,1009,37.9584,0.30355221,0,0,,,,,,,,,2.00E-81,CHOYP_FBXO47.1.1,,,,,,,,, comp134010_c0_seq2,1653,38.1125,0.33487217,56,3,,6.00E-83,Q5MNV8,F-box only protein 47,F-box only protein 47,,,PF00646;,,,1.00E-15,ruditapes_c30150,,,,,FBX47_HUMAN,Homo sapiens (Human), comp134011_c0_seq1,2542,35.7592,0.81266475,416,45566,female>male,3.00E-30,O11780,Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP),Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF02469;,,,3.00E-38,ruditapes2_c2896,,,,,BGH3_PIG,Sus scrofa (Pig),cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; extracellular matrix organization [GO:0030198] comp134020_c4_seq1,3404,32.1974,0.39876534,1237,1211,,,,,,,,,,,9.00E-21,ruditapes_c20313,,,,,,, comp134032_c0_seq2,560,39.6429,0.50150505,5,3,,1.00E-09,Q6ZNG9,KRAB-A domain-containing protein 2,KRAB-A domain-containing protein 2,GO:0015074; GO:0005622; GO:0003676; GO:0006355,"DNA integration; intracellular; nucleic acid binding; regulation of transcription, DNA-dependent",PF01352;,,,,,,,,,KRBA2_HUMAN,Homo sapiens (Human),"DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]" comp134035_c3_seq1,524,41.4122,0.58035926,22,12,,5.00E-56,Q27421,Protein outspread,Protein outspread,GO:0005543,phospholipid binding,PF00169;,2.00E-53,CHOYP_GOGB1.1.2,,,,,,,OSP_DROME,Drosophila melanogaster (Fruit fly), comp134035_c8_seq1,1053,43.4948,0.58537666,23,140,,7.00E-26,Q99KW3,TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin),TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin),GO:0015629; GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0005634; GO:0005543; GO:1900026,actin cytoskeleton; cell division; cytoplasm; microtubule organizing center; midbody; mitosis; nucleus; phospholipid binding; positive regulation of substrate adhesion-dependent cell spreading,PF00169;,2.00E-57,CHOYP_GOGB1.2.2,,,,,,,TARA_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956] comp134037_c0_seq2,1489,33.7139,0.38681222,5,27,,2.00E-63,P60899,DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5),DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5),GO:0003677; GO:0005665; GO:0003899; GO:0006366; GO:0008270,"DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; transcription from RNA polymerase II promoter; zinc ion binding",PF02150;PF01096;,5.00E-79,CHOYP_LOC101071441.1.1,9.00E-93,ruditapes_c7257,2.00E-79,AM860755.p.cg.6,9,,RPB9_PIG,Sus scrofa (Pig),maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter [GO:0001193]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp134038_c0_seq1,3237,34.013,0.41298529,345,1455,,0,Q9BXS5,AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adapter-related protein complex 1 subunit mu-1) (Adaptor protein complex AP-1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin),AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin),GO:0000139; GO:0019886; GO:0030131; GO:0030665; GO:0030659; GO:0005829; GO:0035646; GO:0006886; GO:0005765; GO:0032438; GO:0019048; GO:0006892; GO:0050690; GO:0032588; GO:0016032,Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin adaptor complex; clathrin-coated vesicle membrane; cytoplasmic vesicle membrane; cytosol; endosome to melanosome transport; intracellular protein transport; lysosomal membrane; melanosome organization; modulation by virus of host morphology or physiology; post-Golgi vesicle-mediated transport; regulation of defense response to virus by virus; trans-Golgi network membrane; viral process,PF00928;PF01217;,0,CHOYP_AP1M1.1.1,2.00E-85,ruditapes_c27275,,,,,AP1M1_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; regulation of defense response to virus by virus [GO:0050690]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032] comp134041_c0_seq2,2190,40.411,0.42811902,0,7,,8.00E-59,Q96M60,Protein FAM227B,Protein FAM227B,,,PF14922;,5.00E-56,CHOYP_BRAFLDRAFT_118523.1.1,,,,,,,F227B_HUMAN,Homo sapiens (Human), comp134042_c0_seq4,1036,39.0927,0.94635546,0,12,,2.00E-12,O15375,Monocarboxylate transporter 6 (MCT 6) (Monocarboxylate transporter 5) (MCT 5) (Solute carrier family 16 member 5),Monocarboxylate transporter 6 (MCT 6) (Monocarboxylate transporter 5) (MCT 5) (Solute carrier family 16 member 5),GO:0005887; GO:0008028; GO:0015355; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT6_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp134044_c0_seq1,2997,41.8418,0.39603395,320,1208,,0,P38935,DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2),DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2),GO:0005524; GO:0043141; GO:0032575; GO:0006310; GO:0006281; GO:0006260; GO:0030424; GO:0008219; GO:0005737; GO:0030426; GO:0005634; GO:0051260; GO:0006355; GO:0030529; GO:0043022; GO:0003697; GO:0000049; GO:0006351; GO:0006412; GO:0008270,"ATP binding; ATP-dependent 5'-3' DNA helicase activity; ATP-dependent 5'-3' RNA helicase activity; DNA recombination; DNA repair; DNA replication; axon; cell death; cytoplasm; growth cone; nucleus; protein homooligomerization; regulation of transcription, DNA-dependent; ribonucleoprotein complex; ribosome binding; single-stranded DNA binding; tRNA binding; transcription, DNA-dependent; translation; zinc ion binding",PF01424;PF01428;,1.00E-127,CHOYP_LOC591177.1.1,,,,,,,SMBP2_HUMAN,Homo sapiens (Human),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; protein homooligomerization [GO:0051260]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]" comp134045_c4_seq2,847,38.0165,0.84153817,1,27,,,,,,,,,,,1.00E-17,ruditapes_c21958,,,,,,, comp134045_c4_seq4,876,37.8995,0.84093785,7,141,,1.00E-35,O75897,Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),GO:0050427; GO:0005829; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1C4_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923] comp134047_c0_seq1,1289,37.3933,0.31310156,0,0,,1.00E-51,Q8VEL0,Motile sperm domain-containing protein 1,Motile sperm domain-containing protein 1,GO:0016021; GO:0000122; GO:0005634; GO:0048471; GO:0045944; GO:0005198,integral to membrane; negative regulation of transcription from RNA polymerase II promoter; nucleus; perinuclear region of cytoplasm; positive regulation of transcription from RNA polymerase II promoter; structural molecule activity,PF00635;,,,,,,,,,MSPD1_MOUSE,Mus musculus (Mouse),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp134047_c0_seq3,403,43.4243,0.58061502,0,0,,,,,,,,,2.00E-59,CHOYP_UBP20.1.2,,,,,,,,, comp134048_c5_seq1,2546,38.7274,0.57895942,22,96,,0,Q28653,Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta),Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta),GO:0005634; GO:0000159; GO:0008601; GO:0007165,nucleus; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; signal transduction,PF01603;,,,,,,,,,2A5D_RABIT,Oryctolagus cuniculus (Rabbit),signal transduction [GO:0007165] comp134048_c5_seq6,1753,39.5322,0.46947053,1,6,,0,Q28653,Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta),Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta),GO:0005634; GO:0000159; GO:0008601; GO:0007165,nucleus; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; signal transduction,PF01603;,0,CHOYP_2A5D.3.3,1.00E-105,ruditapes_c9861,,,,,2A5D_RABIT,Oryctolagus cuniculus (Rabbit),signal transduction [GO:0007165] comp13404_c0_seq1,307,53.4202,0.7929813,6,0,,6.00E-28,P49013,Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),GO:0005509; GO:0005615,calcium ion binding; extracellular space,PF01382;PF00431;PF00008;,1.00E-15,CHOYP_LOC582329.1.2,,,,,,,FBP3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp134051_c0_seq7,1944,36.8313,0.9881665,17,406,,,,,,,,,,,2.00E-14,ruditapes2_c2246,,,,,,, comp134052_c0_seq1,1654,42.2612,1.00841549,256,3161,,6.00E-32,Q8MP06,Senecionine N-oxygenase (SNO) (EC 1.14.13.101),Senecionine N-oxygenase (SNO) (EC 1.14.13.101),GO:0004499; GO:0050661; GO:0009820; GO:0005576; GO:0050660; GO:0051289; GO:0033784,"N,N-dimethylaniline monooxygenase activity; NADP binding; alkaloid metabolic process; extracellular region; flavin adenine dinucleotide binding; protein homotetramerization; senecionine N-oxygenase activity",PF00743;,,,,,,,,,SNO1_TYRJA,Tyria jacobaeae (Cinnabar moth),alkaloid metabolic process [GO:0009820]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289] comp134055_c0_seq2,926,45.2484,0.49429742,16,80,,5.00E-138,Q9BVL4,Selenoprotein O (SelO),Selenoprotein O (SelO),,,PF02696;,3.00E-99,CHOYP_SELO.1.1,,,,,,,SELO_HUMAN,Homo sapiens (Human), comp134055_c2_seq1,1028,45.1362,0.44407585,30,200,,7.00E-63,Q9BVL4,Selenoprotein O (SelO),Selenoprotein O (SelO),,,PF02696;,,,,,,,,,SELO_HUMAN,Homo sapiens (Human), comp134056_c2_seq3,401,38.9027,0.46283183,14,34,,,,,,,,,,,3.00E-15,ruditapes_c27965,,,,,,, comp134057_c0_seq2,353,41.3598,0.53183525,3,0,,,,,,,,,3.00E-11,CHOYP_LOC100376789.1.1,,,,,,,,, comp134057_c0_seq3,1135,43.7885,0.57312156,3,0,,,,,,,,,1.00E-10,CHOYP_LOC100376789.1.1,,,,,,,,, comp134058_c0_seq1,1602,34.769,0.56524771,2,10,,6.00E-08,Q54BW4,Circularly permutated Ras protein 2 (DdiCPRas2),Circularly permutated Ras protein 2 (DdiCPRas2),GO:0005525; GO:0003924; GO:0004866; GO:0016020; GO:0010951; GO:0007165,GTP binding; GTPase activity; endopeptidase inhibitor activity; membrane; negative regulation of endopeptidase activity; signal transduction,PF00207;PF07703;PF00071;,,,,,,,,,CPAS2_DICDI,Dictyostelium discoideum (Slime mold),signal transduction [GO:0007165] comp134058_c0_seq3,1353,36.9549,0.59662211,28,17,,1.00E-43,P35295,Ras-related protein Rab-20,Ras-related protein Rab-20,GO:0005525; GO:0005794; GO:0045335; GO:0030670; GO:0090383; GO:0090385; GO:0015031; GO:0007264,GTP binding; Golgi apparatus; phagocytic vesicle; phagocytic vesicle membrane; phagosome acidification; phagosome-lysosome fusion; protein transport; small GTPase mediated signal transduction,PF00071;,3.00E-49,CHOYP_LOC583583.1.1,,,,,,,RAB20_MOUSE,Mus musculus (Mouse),phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; regulation of autophagosome assembly [GO:2000785]; small GTPase mediated signal transduction [GO:0007264] comp134059_c0_seq1,1764,45.3515,0.85638067,129,52,,3.00E-33,Q5VT06,Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),GO:0005813; GO:0005737; GO:0005634; GO:0005819,centrosome; cytoplasm; nucleus; spindle,PF01302;,,,,,,,,,CE350_HUMAN,Homo sapiens (Human),microtubule anchoring [GO:0034453] comp134060_c0_seq1,2071,42.5398,0.58925651,15,6,,2.00E-163,Q8VCK5,Kelch-like protein 20 (Kelch-like ECT2-interacting protein),Kelch-like protein 20 (Kelch-like ECT2-interacting protein),GO:0031463; GO:0005794; GO:0016605; GO:0009986; GO:0005737; GO:0019964; GO:0043066; GO:0048471; GO:0043161; GO:0004842,Cul3-RING ubiquitin ligase complex; Golgi apparatus; PML body; cell surface; cytoplasm; interferon-gamma binding; negative regulation of apoptotic process; perinuclear region of cytoplasm; proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF07707;PF00651;PF01344;,0,CHOYP_BRAFLDRAFT_203117.1.1,,,,,,,KLH20_MOUSE,Mus musculus (Mouse),Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to interferon-alpha [GO:0035455] comp134060_c0_seq2,2020,42.7723,0.57457792,10,1,,0,F1MBP6,Kelch-like protein 3,Kelch-like protein 3,GO:0031463; GO:0005856; GO:0005829; GO:0072156; GO:0050801; GO:0070936; GO:0042787; GO:0070294,Cul3-RING ubiquitin ligase complex; cytoskeleton; cytosol; distal tubule morphogenesis; ion homeostasis; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; renal sodium ion absorption,PF07707;PF00651;PF01344;,,,,,,,,,KLHL3_BOVIN,Bos taurus (Bovine),distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294] comp134060_c0_seq3,1091,39.78,0.44062218,2,0,,5.00E-117,Q70JS2,Ring canal kelch homolog (Kelch-like protein 1) [Cleaved into: Kelch short protein],Ring canal kelch homolog (Kelch-like protein 1) [Cleaved into: Kelch short protein],GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF07707;PF00651;PF01344;,8.00E-113,CHOYP_BRAFLDRAFT_203117.1.1,,,,,,,KELC_ANOST,Anopheles stephensi (Indo-Pakistan malaria mosquito), comp134063_c0_seq2,917,43.5115,0.46137664,30,63,,6.00E-06,P52654,Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (dTFIIA-L) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p30 subunit); Transcription initiation factor IIA beta chain (TFIIA p20 subunit)],Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (dTFIIA-L) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p30 subunit); Transcription initiation factor IIA beta chain (TFIIA p20 subunit)],GO:0001129; GO:0045944; GO:0005672,TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly; positive regulation of transcription from RNA polymerase II promoter; transcription factor TFIIA complex,PF03153;,1.00E-15,CHOYP_TF2AA.1.1,,,,,,,TF2AA_DROME,Drosophila melanogaster (Fruit fly),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp134066_c0_seq1,1342,41.1326,1.21750908,94,517,,2.00E-12,O15973,"Rhodopsin, GQ-coupled (GQ-rhodopsin)","Rhodopsin, GQ-coupled (GQ-rhodopsin)",GO:0004930; GO:0016021; GO:0009881; GO:0007602; GO:0018298; GO:0007601,G-protein coupled receptor activity; integral to membrane; photoreceptor activity; phototransduction; protein-chromophore linkage; visual perception,PF00001;,,,,,,,,,OPSD1_MIZYE,Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis),phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; visual perception [GO:0007601] comp134070_c0_seq1,1909,39.2352,0.46676455,0,0,,2.00E-34,Q5RB68,Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),GO:0005737; GO:0005856; GO:0003730; GO:0048027; GO:0051028; GO:0000166; GO:0005634; GO:0006417,cytoplasm; cytoskeleton; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00013;PF00076;,,,,,,,,,IF2B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp134070_c0_seq2,1553,43.1423,0.46613239,0,0,,8.00E-08,Q80WA4,RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Fragment),RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Fragment),GO:0003723; GO:0007399; GO:0005634,RNA binding; nervous system development; nucleus,PF00013;,,,,,,,,,NOVA1_RAT,Rattus norvegicus (Rat),"mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA processing [GO:0050684]; spinal cord development [GO:0021510]" comp134070_c0_seq3,2354,44.5624,0.55576461,0,0,,1.00E-68,O42254,Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zip-code binding polypeptide) (Zipcode-binding protein 1) (ZBP-1),Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zip-code binding polypeptide) (Zipcode-binding protein 1) (ZBP-1),GO:0070937; GO:0070934; GO:0010494; GO:0030175; GO:0030426; GO:0030027; GO:0003730; GO:0048027; GO:0051028; GO:0017148; GO:0000166; GO:0005634; GO:0048471; GO:0005886; GO:0010610; GO:0045182,CRD-mediated mRNA stability complex; CRD-mediated mRNA stabilization; cytoplasmic stress granule; filopodium; growth cone; lamellipodium; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; negative regulation of translation; nucleotide binding; nucleus; perinuclear region of cytoplasm; plasma membrane; regulation of mRNA stability involved in response to stress; translation regulator activity,PF00013;PF00076;,8.00E-35,CHOYP_LOC100114171.1.1,,,,,,,IF2B1_CHICK,Gallus gallus (Chicken),CRD-mediated mRNA stabilization [GO:0070934]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; neuronal stem cell population maintenance [GO:0097150]; pallium cell proliferation in forebrain [GO:0022013]; positive regulation of neuron projection development [GO:0010976]; regulation of mRNA stability involved in response to stress [GO:0010610] comp134070_c0_seq4,2710,41.6236,0.55818123,0,0,,4.00E-69,Q5RB68,Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),GO:0005737; GO:0005856; GO:0003730; GO:0048027; GO:0051028; GO:0000166; GO:0005634; GO:0006417,cytoplasm; cytoskeleton; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00013;PF00076;,,,,,,,,,IF2B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp134073_c0_seq1,1110,41.6216,0.88041581,7,7,,4.00E-93,P51871,Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),GO:0070330; GO:0005789; GO:0020037; GO:0006954; GO:0005506; GO:0006691,aromatase activity; endoplasmic reticulum membrane; heme binding; inflammatory response; iron ion binding; leukotriene metabolic process,PF00067;,6.00E-20,CHOYP_BRAFLDRAFT_61250.5.14,,,,,,,CP4F6_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691] comp134073_c0_seq3,429,40.3263,0.69355216,0,0,,,,,,,,,4.00E-11,CHOYP_BRAFLDRAFT_61250.13.14,,,,,,,,, comp134073_c0_seq4,791,42.225,0.86087094,0,7,,7.00E-71,P15129,Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450 L-2) (Cytochrome P450 isozyme 5),Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450 L-2) (Cytochrome P450 isozyme 5),GO:0070330; GO:0018879; GO:0008144; GO:0005789; GO:0042738; GO:0018917; GO:0018585; GO:0020037; GO:0043231; GO:0005506; GO:0004497,aromatase activity; biphenyl metabolic process; drug binding; endoplasmic reticulum membrane; exogenous drug catabolic process; fluorene metabolic process; fluorene oxygenase activity; heme binding; intracellular membrane-bounded organelle; iron ion binding; monooxygenase activity,PF00067;,5.00E-19,CHOYP_BRAFLDRAFT_61250.8.14,,,,,,,CP4B1_RAT,Rattus norvegicus (Rat),biphenyl metabolic process [GO:0018879]; cellular aromatic compound metabolic process [GO:0006725]; exogenous drug catabolic process [GO:0042738]; fluorene metabolic process [GO:0018917] comp134082_c0_seq1,299,46.8227,0.36742603,71,40,,6.00E-08,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,6.00E-19,CHOYP_BRAFLDRAFT_125670.1.1,,,,,,,CL063_HUMAN,, comp134082_c0_seq2,300,41.6667,0.39091343,23,0,,,,,,,,,7.00E-18,CHOYP_LOC575277.2.2,,,,,,,,, comp134083_c0_seq1,1229,40.5207,1.0145239,4,0,,3.00E-56,Q6ZNI0,"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 (EC 2.4.1.-)","Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 (EC 2.4.1.-)",GO:0000139; GO:0008375; GO:0016021; GO:0006486,Golgi membrane; acetylglucosaminyltransferase activity; integral to membrane; protein glycosylation,PF02485;,,,,,,,,,GCNT7_HUMAN,Homo sapiens (Human),protein glycosylation [GO:0006486] comp134083_c0_seq5,1847,37.5744,1.09121788,28,52,,3.00E-76,Q09324,"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)","Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)",GO:0031985; GO:0000139; GO:0003829; GO:0060352; GO:0009101; GO:0016021; GO:0060993; GO:0050901; GO:0006486; GO:0048729,"Golgi cisterna; Golgi membrane; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; cell adhesion molecule production; glycoprotein biosynthetic process; integral to membrane; kidney morphogenesis; leukocyte tethering or rolling; protein glycosylation; tissue morphogenesis",PF02485;,,,,,,,,,GCNT1_MOUSE,Mus musculus (Mouse),cell adhesion molecule production [GO:0060352]; glycoprotein biosynthetic process [GO:0009101]; kidney morphogenesis [GO:0060993]; leukocyte tethering or rolling [GO:0050901]; protein glycosylation [GO:0006486]; response to insulin [GO:0032868]; tissue morphogenesis [GO:0048729] comp134086_c0_seq4,495,29.4949,1.11775104,5,3,,2.00E-10,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp134089_c2_seq1,1338,39.3871,0.65571115,43,278,,1.00E-99,Q7SXP8,Mannose-1-phosphate guanyltransferase alpha-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-B) (GTP-mannose-1-phosphate guanylyltransferase apha-B),Mannose-1-phosphate guanyltransferase alpha-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-B) (GTP-mannose-1-phosphate guanylyltransferase alpha-b),GO:0009298; GO:0005525; GO:0004475,GDP-mannose biosynthetic process; GTP binding; mannose-1-phosphate guanylyltransferase activity,PF00132;PF00483;,3.00E-49,CHOYP_GMPAA.1.1,,,,,,,GMPAB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),GDP-mannose biosynthetic process [GO:0009298] comp134092_c0_seq1,273,52.0147,0.38669874,37,36,,,,,,,,,1.00E-21,CHOYP_LOC100892567.7.8,,,,,,,,, comp134095_c0_seq1,882,37.7551,0.22354459,5,0,,8.00E-29,Q0VFE3,Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1),Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1),GO:0006506; GO:0006505; GO:0000139; GO:0016788; GO:0016021; GO:0031227,"GPI anchor biosynthetic process; GPI anchor metabolic process; Golgi membrane; hydrolase activity, acting on ester bonds; integral to membrane; intrinsic to endoplasmic reticulum membrane",PF04080;,3.00E-15,CHOYP_LOC663374.1.1,,,,,,,PGAP3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505] comp134097_c1_seq1,1146,42.9319,0.41722915,70,258,,3.00E-33,Q5RAM8,ELL-associated factor 1,ELL-associated factor 1,GO:0015030; GO:0032783; GO:0016607; GO:0006355; GO:0006351,"Cajal body; ELL-EAF complex; nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09816;,4.00E-22,CHOYP_LOC100707027.1.1,,,,,,,EAF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134104_c0_seq1,1329,33.7848,0.37549428,0,0,,,,,,,,,8.00E-51,CHOYP_LSM8.1.2,,,,,,,,, comp134104_c0_seq2,1368,34.1374,0.35611316,26,83,,2.00E-44,Q5RCP3,"N-alpha-acetyltransferase 38, NatC auxiliary subunit (U6 snRNA-associated Sm-like protein LSm8)",U6 snRNA-associated Sm-like protein LSm8,GO:0003723; GO:0008380; GO:0006397; GO:0005681,RNA binding; RNA splicing; mRNA processing; spliceosomal complex,PF01423;,1.00E-47,CHOYP_LSM8.2.2,,,,,,,NAA38_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp134105_c0_seq1,2042,44.1234,1.05723268,2942,27074,,1.00E-162,P09487,"Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme)","Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme)",GO:0004035; GO:0031225; GO:0046872; GO:0005886; GO:0033280,alkaline phosphatase activity; anchored to membrane; metal ion binding; plasma membrane; response to vitamin D,PF00245;,1.00E-30,CHOYP_LOC101158849.1.1,1.00E-36,ruditapes_c16476,,,,,PPBT_BOVIN,Bos taurus (Bovine),biomineral tissue development [GO:0031214]; cellular response to organic cyclic compound [GO:0071407]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; osteoblast differentiation [GO:0001649]; response to antibiotic [GO:0046677]; response to vitamin D [GO:0033280] comp134114_c0_seq1,1330,40.1504,1.02710762,68,309,,7.00E-29,P05044,Sorcin (22 kDa protein) (CP-22) (V19),Sorcin (22 kDa protein) (CP-22) (V19),GO:0005509; GO:0016020; GO:0033017,calcium ion binding; membrane; sarcoplasmic reticulum membrane,PF13405;PF13833;,9.00E-12,CHOYP_LOC100554313.1.1,1.00E-65,ruditapes_c14217,,,,,SORCN_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus), comp134122_c0_seq1,1047,40.2101,0.52139351,46,325,,5.00E-75,Q24087,DNA repair endonuclease XPF (EC 3.1.-.-) (Protein meiotic 9),DNA repair endonuclease XPF (EC 3.1.-.-) (Protein meiotic 9),GO:0000724; GO:0016321; GO:0000710; GO:0007095; GO:0000110; GO:0006296; GO:0000712; GO:0003697; GO:0000014,"double-strand break repair via homologous recombination; female meiosis chromosome segregation; meiotic mismatch repair; mitotic G2 DNA damage checkpoint; nucleotide-excision repair factor 1 complex; nucleotide-excision repair, DNA incision, 5'-to lesion; resolution of meiotic recombination intermediates; single-stranded DNA binding; single-stranded DNA endodeoxyribonuclease activity",PF02732;,,,1.00E-18,ruditapes_c13215,,,,,XPF_DROME,Drosophila melanogaster (Fruit fly),"cellular response to DNA damage stimulus [GO:0006974]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis chromosome segregation [GO:0016321]; female meiotic division [GO:0007143]; meiotic chromosome segregation [GO:0045132]; mismatch repair [GO:0006298]; mitotic G2 DNA damage checkpoint [GO:0007095]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]" comp134122_c1_seq1,1433,43.4752,0.37353106,7,11,,,,,,,,,1.00E-99,CHOYP_XPF.1.1,,,,,,,,, comp134122_c1_seq2,1244,44.2122,0.38290301,0,0,,4.00E-119,Q9QZD4,DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4),DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4),GO:0001094; GO:0009650; GO:0003684; GO:0000724; GO:0000710; GO:0032205; GO:0000784; GO:0000110; GO:0006295; GO:0006296; GO:0000712; GO:0003697; GO:0000014; GO:0010834; GO:0005669,"TFIID-class transcription factor binding; UV protection; damaged DNA binding; double-strand break repair via homologous recombination; meiotic mismatch repair; negative regulation of telomere maintenance; nuclear chromosome, telomeric region; nucleotide-excision repair factor 1 complex; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; resolution of meiotic recombination intermediates; single-stranded DNA binding; single-stranded DNA endodeoxyribonuclease activity; telomere maintenance via telomere shortening; transcription factor TFIID complex",PF02732;,,,,,,,,,XPF_MOUSE,Mus musculus (Mouse),"cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; UV protection [GO:0009650]" comp134123_c0_seq1,469,47.7612,0.45323253,27,0,,7.00E-12,Q8N9B4,Ankyrin repeat domain-containing protein 42,Ankyrin repeat domain-containing protein 42,GO:0005634; GO:0051092; GO:1900017,nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production involved in inflammatory response,PF12796;,4.00E-42,CHOYP_ANKRD5.1.2,4.00E-47,ruditapes_c25021,,,,,ANR42_HUMAN,Homo sapiens (Human), comp134123_c0_seq2,1750,44.9714,0.40442548,135,19,,2.00E-104,Q9D2J7,Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5),Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5),GO:0005509,calcium ion binding,PF12796;,6.00E-136,CHOYP_ANKRD5.1.2,,,,,,,ANKR5_MOUSE,Mus musculus (Mouse), comp134123_c2_seq1,329,43.1611,0.46573011,15,0,,3.00E-06,Q2TB02,NF-kappa-B inhibitor delta (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS),NF-kappa-B inhibitor delta (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS),GO:0006954; GO:0043124; GO:0032088; GO:0033085; GO:0005634; GO:0070245,inflammatory response; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB transcription factor activity; negative regulation of T cell differentiation in thymus; nucleus; positive regulation of thymocyte apoptotic process,PF00023;PF12796;,,,,,,,,,IKBD_MOUSE,Mus musculus (Mouse),inflammatory response [GO:0006954]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation in thymus [GO:0033085]; positive regulation of thymocyte apoptotic process [GO:0070245]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp134126_c0_seq1,883,37.2593,0.54975195,720,3153,,1.00E-18,Q2NL27,"28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt)","28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF10484;,,,,,,,,,RT23_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp134127_c0_seq2,362,38.9503,0.66453596,0,7,,1.00E-09,Q9GNQ1,18 kDa learning-associated protein of slug,18 kDa learning-associated protein of slug,GO:0005737; GO:0005576; GO:0007616,cytoplasm; extracellular region; long-term memory,PF10169;,,,,,,,,,LPS18_LIMMA,Lehmannia marginata (Tree slug) (Limax marginatus),learning or memory [GO:0007611]; long-term memory [GO:0007616] comp134128_c0_seq1,1579,41.8619,0.49183349,4,7,,1.00E-19,P08F94,Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),GO:0031362; GO:0016324; GO:0016337; GO:0005813; GO:0042384; GO:0005737; GO:0042592; GO:0016021; GO:0001822; GO:0005932; GO:0072686; GO:0051271; GO:0072372; GO:0004872; GO:0010824,anchored to external side of plasma membrane; apical plasma membrane; cell-cell adhesion; centrosome; cilium assembly; cytoplasm; homeostatic process; integral to membrane; kidney development; microtubule basal body; mitotic spindle; negative regulation of cellular component movement; primary cilium; receptor activity; regulation of centrosome duplication,PF10162;PF01833;,,,,,,,,,PKHD1_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337] comp134128_c0_seq3,1636,42.176,0.4951397,21,0,,2.00E-47,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp134131_c0_seq1,944,37.7119,0.48461593,110,877,,4.00E-88,Q8K1A0,Methyltransferase-like protein 5 (EC 2.1.1.-),Methyltransferase-like protein 5 (EC 2.1.1.-),GO:0008168; GO:0003676,methyltransferase activity; nucleic acid binding,PF05175;,,,,,,,,,METL5_MOUSE,Mus musculus (Mouse), comp134133_c4_seq2,925,33.5135,0.46321285,25,234,,,,,,,,,,,7.00E-16,ruditapes_c31873,,,,,,, comp134136_c0_seq1,1477,40.149,0.42395265,3,44,,3.00E-119,Q8C2L6,Transmembrane protein 161B,Transmembrane protein 161B,GO:0016021,integral to membrane,PF10268;,,,,,,,,,T161B_MOUSE,Mus musculus (Mouse), comp134139_c0_seq3,3005,40.0666,0.38049032,0,0,,3.00E-19,Q92805,Golgin subfamily A member 1 (Golgin-97),Golgin subfamily A member 1 (Golgin-97),GO:0005794; GO:0032580; GO:0048471; GO:0000042; GO:0005802,Golgi apparatus; Golgi cisterna membrane; perinuclear region of cytoplasm; protein targeting to Golgi; trans-Golgi network,PF01465;,,,,,,,,,GOGA1_HUMAN,Homo sapiens (Human),protein targeting to Golgi [GO:0000042] comp134139_c0_seq4,1871,39.9786,0.40568666,0,0,,,,,,,,,4.00E-31,CHOYP_LOC100888300.2.2,,,,,,,,, comp134139_c0_seq7,2912,40.3159,0.37022953,0,0,,3.00E-19,Q92805,Golgin subfamily A member 1 (Golgin-97),Golgin subfamily A member 1 (Golgin-97),GO:0005794; GO:0032580; GO:0048471; GO:0000042; GO:0005802,Golgi apparatus; Golgi cisterna membrane; perinuclear region of cytoplasm; protein targeting to Golgi; trans-Golgi network,PF01465;,,,,,,,,,GOGA1_HUMAN,Homo sapiens (Human),protein targeting to Golgi [GO:0000042] comp134139_c0_seq8,2837,40.5358,0.37584083,0,0,,,,,,,,,6.00E-31,CHOYP_LOC100888300.2.2,,,,,,,,, comp134139_c0_seq9,1089,41.5978,0.33033,0,0,,1.00E-10,Q9CW79,Golgin subfamily A member 1 (Golgin-97),Golgin subfamily A member 1 (Golgin-97),GO:0005794; GO:0032580; GO:0048471; GO:0000042; GO:0005802,Golgi apparatus; Golgi cisterna membrane; perinuclear region of cytoplasm; protein targeting to Golgi; trans-Golgi network,PF01465;,,,,,,,,,GOGA1_MOUSE,Mus musculus (Mouse),protein targeting to Golgi [GO:0000042] comp134140_c0_seq7,806,38.4615,0.6765604,58,118,,2.00E-43,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp134142_c0_seq1,1833,43.2079,1.01790119,0,0,,7.00E-18,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp134142_c0_seq2,1856,43.1573,1.03050909,0,0,,5.00E-16,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,,,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp134142_c0_seq3,1732,42.9561,1.02690394,0,0,,1.00E-08,Q9EP71,Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) (p125),Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) (p125),GO:0005938; GO:0005856; GO:0005739; GO:0005634,cell cortex; cytoskeleton; mitochondrion; nucleus,PF00023;PF12796;,,,,,,,,,RAI14_MOUSE,Mus musculus (Mouse), comp134142_c0_seq4,1709,43.0076,1.01306353,0,0,,6.00E-12,A2A2Z9,Ankyrin repeat domain-containing protein 18B,Ankyrin repeat domain-containing protein 18B,,,PF12796;PF12001;,,,,,,,,,AN18B_HUMAN,Homo sapiens (Human), comp134146_c0_seq1,839,44.1001,0.48467985,0,0,,8.00E-96,Q9BY41,Histone deacetylase 8 (HD8) (EC 3.5.1.98),Histone deacetylase 8 (HD8) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0006333; GO:0005829; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0046872; GO:0000278; GO:0000122; GO:0000228; GO:0071922; GO:0007062; GO:0008134; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); chromatin assembly or disassembly; cytosol; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; metal ion binding; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; nuclear chromosome; regulation of cohesin localization to chromatin; sister chromatid cohesion; transcription factor binding; transcription, DNA-dependent",PF00850;,2.00E-25,CHOYP_LOC100373017.1.1,,,,,,,HDAC8_HUMAN,Homo sapiens (Human),"chromatin assembly or disassembly [GO:0006333]; chromatin modification [GO:0016568]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]; transcription, DNA-templated [GO:0006351]" comp134146_c0_seq2,591,39.4247,0.36125199,27,93,,1.00E-18,Q9LXN8,Histone deacetylase 17 (EC 3.5.1.98),Histone deacetylase 17 (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0070932; GO:0070933; GO:0005634; GO:0006355; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone H3 deacetylation; histone H4 deacetylation; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,HDA17_ARATH,Arabidopsis thaliana (Mouse-ear cress),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134146_c0_seq3,977,42.8864,0.46040911,21,14,,3.00E-95,Q9BY41,Histone deacetylase 8 (HD8) (EC 3.5.1.98),Histone deacetylase 8 (HD8) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0006333; GO:0005829; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0046872; GO:0000278; GO:0000122; GO:0000228; GO:0071922; GO:0007062; GO:0008134; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); chromatin assembly or disassembly; cytosol; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; metal ion binding; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; nuclear chromosome; regulation of cohesin localization to chromatin; sister chromatid cohesion; transcription factor binding; transcription, DNA-dependent",PF00850;,,,,,,,,,HDAC8_HUMAN,Homo sapiens (Human),"chromatin assembly or disassembly [GO:0006333]; chromatin modification [GO:0016568]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]; transcription, DNA-templated [GO:0006351]" comp134147_c1_seq11,379,41.4248,0.18536714,19,5,,1.00E-07,Q8BR93,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_MOUSE,Mus musculus (Mouse), comp134150_c0_seq5,784,38.5204,0.62674753,0,0,,3.00E-11,D3ZQX4,Anaphase-promoting complex subunit 15 (APC15),Anaphase-promoting complex subunit 15 (APC15),GO:0005680; GO:0051301; GO:0007067; GO:0090266,anaphase-promoting complex; cell division; mitosis; regulation of mitotic cell cycle spindle assembly checkpoint,PF15243;,7.00E-49,CHOYP_BRAFLDRAFT_126681.1.1,,,,,,,APC15_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] comp134156_c0_seq1,1241,41.9017,0.62025797,4,10,,1.00E-110,Q5U4Q6,Golgi phosphoprotein 3-like,Golgi phosphoprotein 3-like,GO:0031985; GO:0032580; GO:0007030; GO:0070273; GO:0050714; GO:0005802,Golgi cisterna; Golgi cisterna membrane; Golgi organization; phosphatidylinositol-4-phosphate binding; positive regulation of protein secretion; trans-Golgi network,PF05719;,4.00E-118,CHOYP_GOLP3.1.1,,,,,,,GLP3L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; positive regulation of protein secretion [GO:0050714] comp134156_c0_seq2,1412,40.864,0.72527106,11,43,,5.00E-131,Q9H4A6,Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS),Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS),GO:0031985; GO:0032580; GO:0007030; GO:0043001; GO:0048194; GO:0060352; GO:0008283; GO:0005829; GO:0005768; GO:0010467; GO:0009101; GO:0030032; GO:0050901; GO:0005758; GO:0005739; GO:0031965; GO:0070273; GO:0005886; GO:0032008; GO:0050714; GO:0045053; GO:0009306; GO:0010821; GO:0005802,Golgi cisterna; Golgi cisterna membrane; Golgi organization; Golgi to plasma membrane protein transport; Golgi vesicle budding; cell adhesion molecule production; cell proliferation; cytosol; endosome; gene expression; glycoprotein biosynthetic process; lamellipodium assembly; leukocyte tethering or rolling; mitochondrial intermembrane space; mitochondrion; nuclear membrane; phosphatidylinositol-4-phosphate binding; plasma membrane; positive regulation of TOR signaling cascade; positive regulation of protein secretion; protein retention in Golgi apparatus; protein secretion; regulation of mitochondrion organization; trans-Golgi network,PF05719;,7.00E-109,CHOYP_MCMBP.1.2,,,,,,,GOLP3_HUMAN,Homo sapiens (Human),asymmetric Golgi ribbon formation [GO:0090164]; cell adhesion molecule production [GO:0060352]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; gene expression [GO:0010467]; glycoprotein biosynthetic process [GO:0009101]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle budding [GO:0048194]; lamellipodium assembly [GO:0030032]; leukocyte tethering or rolling [GO:0050901]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]; positive regulation of TOR signaling [GO:0032008]; protein retention in Golgi apparatus [GO:0045053]; protein secretion [GO:0009306]; regulation of mitochondrion organization [GO:0010821] comp134161_c0_seq2,497,37.4245,0.98614261,0,8,,5.00E-07,Q3KQV3,Zinc finger protein 792,Zinc finger protein 792,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN792_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134164_c0_seq1,1057,36.6131,0.55450783,8875,224,,2.00E-07,Q5ZMD4,Tripartite motif-containing protein 59,Tripartite motif-containing protein 59,GO:0016021; GO:0005622; GO:0008270,integral to membrane; intracellular; zinc ion binding,PF00643;PF13445;,,,,,,,,,TRI59_CHICK,Gallus gallus (Chicken),cilium assembly [GO:0042384] comp134169_c2_seq11,252,36.9048,0.84094392,0,3,,,,,,,,,4.00E-14,CHOYP_contig_039795,,,,,,,,, comp134173_c1_seq1,1085,37.5115,0.31501115,0,0,,3.00E-88,Q5I0H4,Transmembrane and coiled-coil domains protein 1 (Meg-2-like protein),Calcium load-activated calcium channel (CLAC channel) (Meg-2-like protein) (Transmembrane and coiled-coil domain-containing protein 1),GO:0000139; GO:0005789; GO:0016021,Golgi membrane; endoplasmic reticulum membrane; integral to membrane,PF01956;,3.00E-99,CHOYP_DGRI_GH10893.1.1,,,,,,,TMCO1_RAT,Rattus norvegicus (Rat),calcium ion transmembrane transport [GO:0070588]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983] comp134173_c1_seq4,890,38.5393,0.24236685,0,0,,3.00E-89,Q5I0H4,Transmembrane and coiled-coil domains protein 1 (Meg-2-like protein),Calcium load-activated calcium channel (CLAC channel) (Meg-2-like protein) (Transmembrane and coiled-coil domain-containing protein 1),GO:0000139; GO:0005789; GO:0016021,Golgi membrane; endoplasmic reticulum membrane; integral to membrane,PF01956;,2.00E-99,CHOYP_DGRI_GH10893.1.1,,,,,,,TMCO1_RAT,Rattus norvegicus (Rat),calcium ion transmembrane transport [GO:0070588]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983] comp134174_c0_seq1,894,39.5973,0.68223331,0,0,,,,,,,,,1.00E-45,CHOYP_LOC755300.1.1,,,,,,,,, comp134174_c0_seq2,960,39.1667,0.70713837,6,0,,6.00E-77,Q58E03,DnaJ homolog subfamily C member 25,DnaJ homolog subfamily C member 25,GO:0016021,integral to membrane,PF00226;,,,,,,,,,DJC25_XENLA,Xenopus laevis (African clawed frog), comp134184_c0_seq1,1269,42.7108,0.39792954,41,143,,1.00E-08,Q3MHV6,SLAIN motif-containing protein 2,SLAIN motif-containing protein 2,GO:0005813; GO:0005737; GO:0031122; GO:0015630; GO:0007020; GO:0035371; GO:0031116,centrosome; cytoplasm; cytoplasmic microtubule organization; microtubule cytoskeleton; microtubule nucleation; microtubule plus end; positive regulation of microtubule polymerization,PF15301;,1.00E-17,CHOYP_SLAI2.2.2,1.00E-40,ruditapes_c28538,,,,,SLAI2_BOVIN,Bos taurus (Bovine),cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]; positive regulation of microtubule polymerization [GO:0031116] comp134185_c0_seq2,1452,40.2893,0.95486702,3,239,,,,,,,,,9.00E-32,CHOYP_ZPR_4288.1.1,5.00E-32,ruditapes_c19402,,,,,,, comp134187_c0_seq2,1875,36.9067,0.54510664,78,196,,2.00E-66,Q8VIP2,Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein),Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein),GO:0035538; GO:0071333; GO:0005829; GO:0055089; GO:0005654; GO:2000505; GO:0006110; GO:0006357; GO:0043565; GO:0003700; GO:0006351,"carbohydrate response element binding; cellular response to glucose stimulus; cytosol; fatty acid homeostasis; nucleoplasm; regulation of energy homeostasis; regulation of glycolysis; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00010;,1.00E-81,CHOYP_LOC101078430.1.1,,,,,,,MLXPL_RAT,Rattus norvegicus (Rat),"cellular response to glucose stimulus [GO:0071333]; energy reserve metabolic process [GO:0006112]; fatty acid homeostasis [GO:0055089]; regulation of energy homeostasis [GO:2000505]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of glycolytic process [GO:0006110]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to glucose [GO:0009749]; transcription, DNA-templated [GO:0006351]" comp134189_c2_seq1,1330,42.1053,0.34095004,237,1586,,1.00E-46,Q9CQQ4,Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1),Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1),GO:0097504; GO:0005737; GO:0005634; GO:0005681; GO:0000245; GO:0000387,Gemini of coiled bodies; cytoplasm; nucleus; spliceosomal complex; spliceosomal complex assembly; spliceosomal snRNP assembly,,,,,,,,,,GEMI2_MOUSE,Mus musculus (Mouse),spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387] comp134191_c0_seq1,967,37.1251,0.46691155,7,174,,4.00E-36,Q6TEC1,U8 snoRNA-decapping enzyme (EC 3.6.1.62) (IDP phosphatase) (IDPase) (EC 3.6.1.-) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (U8 snoRNA-binding protein X29) (m7GpppN-mRNA hydrolase),U8 snoRNA-decapping enzyme (EC 3.6.1.62) (IDP phosphatase) (IDPase) (EC 3.6.1.64) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (U8 snoRNA-binding protein X29) (m7GpppN-mRNA hydrolase),GO:0005525; GO:0046709; GO:1901641; GO:1901639; GO:1901640; GO:0006382; GO:0050897; GO:0005737; GO:0035863; GO:0035870; GO:0050072; GO:0003729; GO:0006402; GO:0000287; GO:0030145; GO:0008235; GO:2000233; GO:0005730; GO:0005654; GO:0090068; GO:0008284; GO:2000781; GO:0042803; GO:0030515; GO:0016077,GTP binding; IDP catabolic process; ITP binding; XDP catabolic process; XTP binding; adenosine to inosine editing; cobalt ion binding; cytoplasm; dITP catabolic process; dITP diphosphatase activity; m7G(5')pppN diphosphatase activity; mRNA binding; mRNA catabolic process; magnesium ion binding; manganese ion binding; metalloexopeptidase activity; negative regulation of rRNA processing; nucleolus; nucleoplasm; positive regulation of cell cycle process; positive regulation of cell proliferation; positive regulation of double-strand break repair; protein homodimerization activity; snoRNA binding; snoRNA catabolic process,PF00293;,2.00E-26,CHOYP_NUD16.1.2,,,,,,,NUD16_XENLA,Xenopus laevis (African clawed frog),adenosine to inosine editing [GO:0006382]; dITP catabolic process [GO:0035863]; IDP catabolic process [GO:0046709]; mRNA catabolic process [GO:0006402]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; positive regulation of cell proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; snoRNA catabolic process [GO:0016077]; XDP catabolic process [GO:1901639] comp134192_c0_seq1,826,41.8886,0.4748867,112,77,,3.00E-17,Q80YE7,Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),GO:0005524; GO:0015629; GO:0005516; GO:0004683; GO:0071346; GO:0005829; GO:0008625; GO:0007243; GO:0043066; GO:1902042; GO:0017148; GO:0046777; GO:0004672; GO:2000310,ATP binding; actin cytoskeleton; calmodulin binding; calmodulin-dependent protein kinase activity; cellular response to interferon-gamma; cytosol; extrinsic apoptotic signaling pathway via death domain receptors; intracellular protein kinase cascade; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of translation; protein autophosphorylation; protein kinase activity; regulation of N-methyl-D-aspartate selective glutamate receptor activity,PF12796;PF00531;PF00069;,,,,,,,,,DAPK1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310] comp134193_c0_seq1,1151,38.0539,0.72132297,4,0,,,,,,,,,3.00E-11,CHOYP_BRAFLDRAFT_106513.1.1,5.00E-38,ruditapes2_c791,,,,,,, comp134193_c0_seq2,1157,38.548,0.65265749,3,0,,1.00E-54,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,4.00E-47,CHOYP_LOC100369190.1.1,,,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp134195_c1_seq1,879,40.7281,0.47696539,0,10,,2.00E-07,Q02724,Ubiquitin-like-specific protease 1 (EC 3.4.22.68),Ubiquitin-like-specific protease 1 (EC 3.4.22.68),GO:0000086; GO:0016929; GO:0005643; GO:0005730; GO:0016926; GO:0006508,G2/M transition of mitotic cell cycle; SUMO-specific protease activity; nuclear pore; nucleolus; protein desumoylation; proteolysis,PF02902;,,,,,,,,,ULP1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),G2/M transition of mitotic cell cycle [GO:0000086]; protein desumoylation [GO:0016926] comp134199_c0_seq2,2132,40.9475,0.4268652,0,0,,6.00E-122,Q924C1,Exportin-5 (Exp5) (Ran-binding protein 21),Exportin-5 (Exp5) (Ran-binding protein 21),GO:0005737; GO:0031047; GO:0005634; GO:0006611; GO:0008565; GO:0000049,cytoplasm; gene silencing by RNA; nucleus; protein export from nucleus; protein transporter activity; tRNA binding,PF08389;,,,,,,,,,XPO5_MOUSE,Mus musculus (Mouse),positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825]; RNA export from nucleus [GO:0006405] comp134199_c0_seq4,2143,40.9706,0.43528245,0,0,,3.00E-129,Q9HAV4,Exportin-5 (Exp5) (Ran-binding protein 21),Exportin-5 (Exp5) (Ran-binding protein 21),GO:0003723; GO:0005829; GO:0010467; GO:0031047; GO:0005654; GO:0006611; GO:0008565; GO:0000049,RNA binding; cytosol; gene expression; gene silencing by RNA; nucleoplasm; protein export from nucleus; protein transporter activity; tRNA binding,PF08389;,,,,,,,,,XPO5_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825] comp134199_c0_seq6,1991,40.7333,0.41393989,0,0,,2.00E-07,Q0WP44,Protein HASTY 1 (Protein HASTY),Protein HASTY 1 (Protein HASTY),GO:0009965; GO:0009910; GO:0005634; GO:0009944; GO:0035281; GO:0048364,leaf morphogenesis; negative regulation of flower development; nucleus; polarity specification of adaxial/abaxial axis; pre-miRNA export from nucleus; root development,PF08389;,5.00E-30,CHOYP_XPO5.1.1,,,,,,,HASTY_ARATH,Arabidopsis thaliana (Mouse-ear cress),leaf morphogenesis [GO:0009965]; negative regulation of flower development [GO:0009910]; polarity specification of adaxial/abaxial axis [GO:0009944]; pre-miRNA export from nucleus [GO:0035281]; regulation of protein export from nucleus [GO:0046825]; root development [GO:0048364]; shoot system development [GO:0048367] comp134199_c0_seq7,2002,40.7592,0.42313506,0,0,,6.00E-114,Q9HAV4,Exportin-5 (Exp5) (Ran-binding protein 21),Exportin-5 (Exp5) (Ran-binding protein 21),GO:0003723; GO:0005829; GO:0010467; GO:0031047; GO:0005654; GO:0006611; GO:0008565; GO:0000049,RNA binding; cytosol; gene expression; gene silencing by RNA; nucleoplasm; protein export from nucleus; protein transporter activity; tRNA binding,PF08389;,,,,,,,,,XPO5_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825] comp134199_c1_seq2,1171,43.5525,0.37859401,10,0,,,,,,,,,5.00E-40,CHOYP_XPO5.1.1,,,,,,,,, comp134200_c0_seq3,1813,41.5885,0.47399723,34,29,,0,Q52I78,Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin),Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin),GO:0009435; GO:0005737; GO:0047280; GO:0004514,NAD biosynthetic process; cytoplasm; nicotinamide phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity,PF04095;,7.00E-161,CHOYP_NEMVEDRAFT_V1G135670.1.1,,,,,,,NAMPT_PIG,Sus scrofa (Pig),circadian regulation of gene expression [GO:0032922]; NAD biosynthetic process [GO:0009435]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp134202_c0_seq2,1041,42.3631,0.75382459,5,0,,5.00E-102,Q9H2F5,Enhancer of polycomb homolog 1,Enhancer of polycomb homolog 1,GO:0032777; GO:0043968; GO:0043967; GO:0045814; GO:0000122; GO:0031965; GO:0045944; GO:0040008; GO:0006351,"Piccolo NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; negative regulation of gene expression, epigenetic; negative regulation of transcription from RNA polymerase II promoter; nuclear membrane; positive regulation of transcription from RNA polymerase II promoter; regulation of growth; transcription, DNA-dependent",PF06752;PF10513;,,,3.00E-20,ruditapes_s38856,,,,,EPC1_HUMAN,Homo sapiens (Human),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]; vascular smooth muscle cell differentiation [GO:0035886]" comp134202_c0_seq3,1559,42.0783,0.67264097,0,11,,2.00E-141,Q8C0I4,Enhancer of polycomb homolog 2 (EPC-like),Enhancer of polycomb homolog 2 (EPC-like),GO:0006281; GO:0032777; GO:0016568; GO:0006355; GO:0006351,"DNA repair; Piccolo NuA4 histone acetyltransferase complex; chromatin modification; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF06752;PF10513;,1.00E-162,CHOYP_LOC100374204.1.1,,,,,,,EPC2_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone acetylation [GO:0016573]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp134202_c0_seq4,2205,42.6757,0.64775677,5,7,,2.00E-16,Q4I5V3,Enhancer of polycomb-like protein 1,Enhancer of polycomb-like protein 1,GO:0006281; GO:0032777; GO:0007049; GO:0006355; GO:0006351,"DNA repair; Piccolo NuA4 histone acetyltransferase complex; cell cycle; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10513;,,,,,,,,,EPL1_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),"cell cycle [GO:0007049]; DNA repair [GO:0006281]; positive regulation of macroautophagy [GO:0016239]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp134202_c0_seq5,2162,42.692,0.65052645,0,0,,2.00E-150,Q9H2F5,Enhancer of polycomb homolog 1,Enhancer of polycomb homolog 1,GO:0032777; GO:0043968; GO:0043967; GO:0045814; GO:0000122; GO:0031965; GO:0045944; GO:0040008; GO:0006351,"Piccolo NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; negative regulation of gene expression, epigenetic; negative regulation of transcription from RNA polymerase II promoter; nuclear membrane; positive regulation of transcription from RNA polymerase II promoter; regulation of growth; transcription, DNA-dependent",PF06752;PF10513;,2.00E-162,CHOYP_LOC100374204.1.1,7.00E-20,ruditapes_lrc32486,,,,,EPC1_HUMAN,Homo sapiens (Human),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]; vascular smooth muscle cell differentiation [GO:0035886]" comp134211_c1_seq1,1397,33.5004,0.43482897,57,127,,,,,,,,,2.00E-20,CHOYP_BRAFLDRAFT_69470.1.1,,,,,,,,, comp134212_c0_seq1,3029,42.7864,0.53799722,209,237,,0,A5PN09,Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20),Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20),GO:0005813; GO:0004197; GO:0006897; GO:0048471; GO:0071108; GO:0070536; GO:0008277; GO:0004221; GO:0006511; GO:0008270,centrosome; cysteine-type endopeptidase activity; endocytosis; perinuclear region of cytoplasm; protein K48-linked deubiquitination; protein K63-linked deubiquitination; regulation of G-protein coupled receptor protein signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF06337;PF00443;PF02148;,3.00E-161,CHOYP_UBP20.2.2,,,,,,,UBP20_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),central nervous system morphogenesis [GO:0021551]; endocytosis [GO:0006897]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511] comp134212_c1_seq1,319,45.1411,0.40134174,19,18,,4.00E-09,Q9P7S5,Probable ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),Probable ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),GO:0005829; GO:0016579; GO:0004221; GO:0006511; GO:0004843; GO:0008270,cytosol; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding,PF00443;PF02148;,,,,,,,,,UBP7_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp134213_c0_seq1,755,41.457,0.97358097,0,249,,1.00E-49,Q868T3,Cardioacceleratory peptide receptor,Cardioacceleratory peptide receptor (Crustacean cardioactive peptide receptor),GO:0018990; GO:0005887; GO:0008188; GO:0005000,"ecdysis, chitin-based cuticle; integral to plasma membrane; neuropeptide receptor activity; vasopressin receptor activity",PF00001;,,,,,,,,,CCAPR_DROME,Drosophila melanogaster (Fruit fly),"ecdysis, chitin-based cuticle [GO:0018990]; G-protein coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]" comp134213_c1_seq2,1191,36.7758,1.10575217,1,82,,3.00E-06,O95977,Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6),Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6),GO:0004930; GO:0007202; GO:0007189; GO:0007204; GO:0006955; GO:0005887; GO:0008289; GO:0038036; GO:0003376,G-protein coupled receptor activity; activation of phospholipase C activity; adenylate cyclase-activating G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; immune response; integral to plasma membrane; lipid binding; sphingosine-1-phosphate receptor activity; sphingosine-1-phosphate signaling pathway,PF00001;,,,,,,,,,S1PR4_HUMAN,Homo sapiens (Human),activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; positive regulation of cytosolic calcium ion concentration [GO:0007204] comp134214_c0_seq1,1035,46.3768,0.68766197,138,108,,1.00E-09,Q05040,Factor arrest protein 8,Factor arrest protein 8,GO:0005783; GO:0000321,endoplasmic reticulum; re-entry into mitotic cell cycle after pheromone arrest,PF08232;,,,,,,,,,FAR8_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),re-entry into mitotic cell cycle after pheromone arrest [GO:0000321] comp134214_c1_seq1,1046,43.5946,0.56876834,13,19,,1.00E-15,O94560,Uncharacterized WD repeat-containing protein C1773.01,Uncharacterized WD repeat-containing protein C1773.01,GO:0090443; GO:0061509; GO:0005737; GO:0031030; GO:0005635; GO:0071957,FAR/SIN/STRIPAK complex; asymmetric protein localization to old mitotic spindle pole body; cytoplasm; negative regulation of septation initiation signaling cascade; nuclear envelope; old mitotic spindle pole body,PF08232;PF00400;,1.00E-91,CHOYP_STRN3.1.5,,,,,,,YGD1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),asymmetric protein localization to old mitotic spindle pole body [GO:0061509]; negative regulation of septation initiation signaling [GO:0031030] comp134214_c1_seq2,830,35.1807,0.78337218,0,0,,5.00E-22,Q70M86,Striatin Pro11,Striatin Pro11,GO:0030154; GO:0016020; GO:0000909,cell differentiation; membrane; sporocarp development involved in sexual reproduction,PF08232;PF00400;,,,,,,,,,STRN_SORMK,Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell),cell differentiation [GO:0030154]; sporocarp development involved in sexual reproduction [GO:0000909] comp134214_c1_seq3,1030,44.2718,0.55920863,0,0,,4.00E-112,A5D7H2,Striatin-3,Striatin-3,GO:0005794; GO:0005737; GO:0000122; GO:0005654; GO:0005886; GO:0045944; GO:0000159; GO:0003700,Golgi apparatus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; plasma membrane; positive regulation of transcription from RNA polymerase II promoter; protein phosphatase type 2A complex; sequence-specific DNA binding transcription factor activity,PF08232;PF00400;,3.00E-86,CHOYP_STRN3.3.5,,,,,,,STRN3_BOVIN,Bos taurus (Bovine),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]" comp134214_c1_seq5,1354,42.0236,0.52422403,0,0,,2.00E-12,Q9WUC8,Pleiotropic regulator 1,Pleiotropic regulator 1,GO:0008380; GO:0071013; GO:0006397; GO:0016607,RNA splicing; catalytic step 2 spliceosome; mRNA processing; nuclear speck,PF00400;,,,,,,,,,PLRG1_RAT,Rattus norvegicus (Rat),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein localization to nucleus [GO:0034504]" comp134214_c1_seq6,811,35.7583,0.77774171,0,0,,2.00E-22,Q70M86,Striatin Pro11,Striatin Pro11,GO:0030154; GO:0016020; GO:0000909,cell differentiation; membrane; sporocarp development involved in sexual reproduction,PF08232;PF00400;,,,,,,,,,STRN_SORMK,Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell),cell differentiation [GO:0030154]; sporocarp development involved in sexual reproduction [GO:0000909] comp134214_c1_seq7,1335,42.4719,0.51984465,0,0,,1.00E-110,A5D7H2,Striatin-3,Striatin-3,GO:0005794; GO:0005737; GO:0000122; GO:0005654; GO:0005886; GO:0045944; GO:0000159; GO:0003700,Golgi apparatus; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; plasma membrane; positive regulation of transcription from RNA polymerase II promoter; protein phosphatase type 2A complex; sequence-specific DNA binding transcription factor activity,PF08232;PF00400;,,,,,,,,,STRN3_BOVIN,Bos taurus (Bovine),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]" comp134215_c0_seq2,850,39.0588,0.40738751,0,6,,7.00E-65,Q503Y4,Ovarian cancer-associated gene 2 protein homolog,Esterase OVCA2 (EC 3.1.2.-) (Ovarian cancer-associated gene 2 protein homolog),,,PF03959;,1.00E-78,CHOYP_BRAFLDRAFT_126058.1.1,1.00E-106,ruditapes2_c1747,,,,,OVCA2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp134216_c0_seq1,1005,34.3284,0.57512836,98,170,,,,,,,,,,,2.00E-11,ruditapes_c7836,,,,,,, comp134217_c0_seq1,1390,45.4676,0.84340559,5,13,,5.00E-81,O16099,Maltase 2 (EC 3.2.1.20),Maltase 2 (EC 3.2.1.20),GO:0005975; GO:0043169; GO:0032450,carbohydrate metabolic process; cation binding; maltose alpha-glucosidase activity,PF00128;,,,,,,,,,MAL2_DROVI,Drosophila virilis (Fruit fly), comp134217_c0_seq2,1355,45.9041,0.83211861,0,2,,5.00E-79,O16099,Maltase 2 (EC 3.2.1.20),Maltase 2 (EC 3.2.1.20),GO:0005975; GO:0043169; GO:0032450,carbohydrate metabolic process; cation binding; maltose alpha-glucosidase activity,PF00128;,3.00E-11,CHOYP_BRAFLDRAFT_220425.4.4,,,,,,,MAL2_DROVI,Drosophila virilis (Fruit fly), comp134221_c0_seq2,1737,37.8238,0.9540777,21,266,,1.00E-56,P15428,15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1),15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1),GO:0016404; GO:0070403; GO:0019371; GO:0005829; GO:0097070; GO:0007565; GO:2001300; GO:0019372; GO:0045786; GO:0005634; GO:0030728; GO:0007567; GO:0004957; GO:0042803; GO:0070493; GO:0007179,15-hydroxyprostaglandin dehydrogenase (NAD+) activity; NAD+ binding; cyclooxygenase pathway; cytosol; ductus arteriosus closure; female pregnancy; lipoxin metabolic process; lipoxygenase pathway; negative regulation of cell cycle; nucleus; ovulation; parturition; prostaglandin E receptor activity; protein homodimerization activity; thrombin receptor signaling pathway; transforming growth factor beta receptor signaling pathway,PF00106;,,,,,,,,,PGDH_HUMAN,Homo sapiens (Human),ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; lipoxin metabolic process [GO:2001300]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; thrombin receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp134222_c0_seq1,1248,45.9135,0.55493334,111,268,,0,P52209,"6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)","6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)",GO:0019521; GO:0050661; GO:0005829; GO:0019322; GO:0009051; GO:0004616,"D-gluconate metabolic process; NADP binding; cytosol; pentose biosynthetic process; pentose-phosphate shunt, oxidative branch; phosphogluconate dehydrogenase (decarboxylating) activity",PF00393;PF03446;,0,CHOYP_NEMVEDRAFT_V1G230495.1.1,,,,,,,6PGD_HUMAN,Homo sapiens (Human),"D-gluconate metabolic process [GO:0019521]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]" comp134224_c0_seq1,1442,40.43,0.47560998,31,145,,8.00E-99,Q28CF8,Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-),Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-),GO:0030659; GO:0016787; GO:0016021; GO:0046872,cytoplasmic vesicle membrane; hydrolase activity; integral to membrane; metal ion binding,PF01150;,1.00E-80,CHOYP_ENTPD4.1.1,,,,,,,ENTP7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp134224_c1_seq2,1150,38.087,0.48141911,4,33,,7.00E-56,Q5REF6,Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-),Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-),GO:0030659; GO:0016787; GO:0016021; GO:0046872,cytoplasmic vesicle membrane; hydrolase activity; integral to membrane; metal ion binding,PF01150;,,,,,,,,,ENTP7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp134227_c0_seq1,1194,33.5846,0.83462269,33,181,,2.00E-07,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp134228_c0_seq1,543,36.2799,0.33788934,8,72,,4.00E-11,P18722,Gastrula zinc finger protein XlCGF46.1 (Fragment),Gastrula zinc finger protein XlCGF46.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG46_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134231_c0_seq1,2308,40.5979,0.62738798,0,3,,3.00E-35,P17027,Zinc finger protein 23 (Zinc finger protein 359) (Zinc finger protein 612) (Zinc finger protein KOX16),Zinc finger protein 23 (Zinc finger protein 359) (Zinc finger protein 612) (Zinc finger protein KOX16),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZNF23_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134231_c0_seq2,3402,40.5938,0.60162099,96,35,,4.00E-39,Q9BSK1,Zinc finger protein 577,Zinc finger protein 577,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN577_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134235_c0_seq1,809,39.8022,0.508635,1,0,,3.00E-25,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp134237_c0_seq3,2353,43.4764,0.34658965,66,116,,0,Q9Y620,DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B),DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B),GO:0005524; GO:0003677; GO:0003678; GO:0015616; GO:0003724; GO:0000724; GO:0006312; GO:0005634; GO:0007131,ATP binding; DNA binding; DNA helicase activity; DNA translocase activity; RNA helicase activity; double-strand break repair via homologous recombination; mitotic recombination; nucleus; reciprocal meiotic recombination,PF00271;PF00176;,2.00E-86,CHOYP_RA54B.1.1,,,,,,,RA54B_HUMAN,Homo sapiens (Human),determination of adult lifespan [GO:0008340]; double-strand break repair via homologous recombination [GO:0000724]; mitotic recombination [GO:0006312]; reciprocal meiotic recombination [GO:0007131]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212] comp134243_c0_seq1,716,31.7039,0.56235404,17,25,,,,,,,,,1.00E-14,CHOYP_contig_024097,,,,,,,,, comp134243_c0_seq7,394,36.802,0.45143148,0,44,,,,,,,,,5.00E-15,CHOYP_contig_046704,,,,,,,,, comp134248_c0_seq1,989,36.1982,0.30959784,44,201,,4.00E-21,Q8T8L8,"Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-2-glucosyltransferase ALG10)","Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-2-glucosyltransferase ALG10)",GO:0005789; GO:0016021; GO:0006486; GO:0016758,"endoplasmic reticulum membrane; integral to membrane; protein glycosylation; transferase activity, transferring hexosyl groups",PF04922;,,,,,,,,,ALG10_DROME,Drosophila melanogaster (Fruit fly),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487] comp134248_c1_seq1,877,38.6545,0.33800002,22,61,,2.00E-53,Q5I7T1,"Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-B) (Asparagine-linked glycosylation protein 10 homolog B) (Potassium channel regulator 1)","Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-B) (Asparagine-linked glycosylation protein 10 homolog B) (Potassium channel regulator 1)",GO:0006488; GO:0016021; GO:0005886; GO:0043687; GO:0018279; GO:0016758,"dolichol-linked oligosaccharide biosynthetic process; integral to membrane; plasma membrane; post-translational protein modification; protein N-linked glycosylation via asparagine; transferase activity, transferring hexosyl groups",PF04922;,1.00E-27,CHOYP_ALDH1L.1.1,,,,,,,AG10B_HUMAN,Homo sapiens (Human),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486] comp134248_c1_seq2,282,40.0709,0.26698449,0,0,,1.00E-11,Q7SA35,"Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase alg-10) (Alpha-2-glucosyltransferase alg-10) (Asparagine-linked glycosylation protein 10) (Dolichyl-phosphoglucose-dependent glucosyltransferase alg-10)","Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase alg-10) (Alpha-2-glucosyltransferase alg-10) (Asparagine-linked glycosylation protein 10) (Dolichyl-phosphoglucose-dependent glucosyltransferase alg-10)",GO:0005789; GO:0016021; GO:0006486; GO:0016758,"endoplasmic reticulum membrane; integral to membrane; protein glycosylation; transferase activity, transferring hexosyl groups",PF04922;,,,,,,,,,ALG10_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486] comp134250_c0_seq1,1117,42.9722,0.54348209,84,388,,2.00E-125,Q99496,E3 ubiquitin-protein ligase RING2 (EC 6.3.2.-) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1),E3 ubiquitin-protein ligase RING2 (EC 6.3.2.-) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1),GO:0071339; GO:0035102; GO:0009948; GO:0003682; GO:0001702; GO:0035518; GO:0016874; GO:0000278; GO:0000122; GO:0016604; GO:0001739; GO:0006351; GO:0000151; GO:0008270,"MLL1 complex; PRC1 complex; anterior/posterior axis specification; chromatin binding; gastrulation with mouth forming second; histone H2A monoubiquitination; ligase activity; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; nuclear body; sex chromatin; transcription, DNA-dependent; ubiquitin ligase complex; zinc ion binding",PF16207;,9.00E-119,CHOYP_BRAFLDRAFT_122927.1.1,1.00E-14,ruditapes_c16131,,,,,RING2_HUMAN,Homo sapiens (Human),"anterior/posterior axis specification [GO:0009948]; gastrulation with mouth forming second [GO:0001702]; germ cell development [GO:0007281]; histone H2A-K119 monoubiquitination [GO:0036353]; histone H2A monoubiquitination [GO:0035518]; mitotic cell cycle [GO:0000278]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein sumoylation [GO:0016925]; response to retinoic acid [GO:0032526]; spinal cord development [GO:0021510]; transcription, DNA-templated [GO:0006351]" comp134251_c0_seq2,1238,43.6995,0.27465451,4,7,,,,,,,,,2.00E-58,CHOYP_LOC101079642.1.1,,,,,,,,, comp134255_c0_seq1,1848,39.9351,0.34256991,6,0,,3.00E-11,Q9CWY3,N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6),N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6),GO:0032088; GO:0005634; GO:0018026; GO:0016279; GO:0050727,negative regulation of NF-kappaB transcription factor activity; nucleus; peptidyl-lysine monomethylation; protein-lysine N-methyltransferase activity; regulation of inflammatory response,PF09273;PF00856;,,,,,,,,,SETD6_MOUSE,Mus musculus (Mouse),histone lysine methylation [GO:0034968]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] comp134255_c0_seq2,1873,39.8825,0.33925685,0,11,,2.00E-162,B0VX69,Histone-lysine N-methyltransferase setd3 (EC 2.1.1.43) (SET domain-containing protein 3),Histone-lysine N-methyltransferase setd3 (EC 2.1.1.43) (SET domain-containing protein 3),GO:0046975; GO:0042800; GO:0000790; GO:0018027; GO:0018026; GO:0018023; GO:0051149; GO:0045944; GO:0045893; GO:0003713; GO:0006351,"histone methyltransferase activity (H3-K36 specific); histone methyltransferase activity (H3-K4 specific); nuclear chromatin; peptidyl-lysine dimethylation; peptidyl-lysine monomethylation; peptidyl-lysine trimethylation; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent",PF09273;PF00856;,6.00E-86,CHOYP_SETD3.1.1,,,,,,,SETD3_CALJA,Callithrix jacchus (White-tufted-ear marmoset),"histone H3-K36 methylation [GO:0010452]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp134256_c0_seq2,796,43.0905,0.43866598,0,0,,,,,,,,,1.00E-27,CHOYP_HGSNAT.1.2,,,,,,,,, comp134256_c0_seq4,822,42.2141,0.44247377,0,0,,4.00E-55,Q3UDW8,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0016746,"heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; transferase activity, transferring acyl groups",PF07786;,,,,,,,,,HGNAT_MOUSE,Mus musculus (Mouse),lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp134259_c0_seq1,1880,40.6915,0.71726219,0,0,,8.00E-50,Q8BN59,La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6),La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6),GO:0005794; GO:0003723; GO:0006396; GO:0000166; GO:0005634; GO:0006417; GO:0030529,Golgi apparatus; RNA binding; RNA processing; nucleotide binding; nucleus; regulation of translation; ribonucleoprotein complex,PF05383;PF12901;,6.00E-86,CHOYP_BRAFLDRAFT_125729.1.1,,,,,,,LARP6_MOUSE,Mus musculus (Mouse),regulation of translation [GO:0006417]; RNA processing [GO:0006396] comp134259_c0_seq3,1798,40.2113,0.67446713,0,0,,,,,,,,,5.00E-86,CHOYP_BRAFLDRAFT_125729.1.1,,,,,,,,, comp134259_c0_seq4,1919,39.1871,0.66222614,0,0,,9.00E-50,Q8BN59,La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6),La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6),GO:0005794; GO:0003723; GO:0006396; GO:0000166; GO:0005634; GO:0006417; GO:0030529,Golgi apparatus; RNA binding; RNA processing; nucleotide binding; nucleus; regulation of translation; ribonucleoprotein complex,PF05383;PF12901;,,,,,,,,,LARP6_MOUSE,Mus musculus (Mouse),regulation of translation [GO:0006417]; RNA processing [GO:0006396] comp134261_c1_seq1,655,42.9008,0.41128623,3,0,,,,,,,,,2.00E-42,CHOYP_LOC100703289.1.1,,,,,,,,, comp134261_c1_seq2,972,42.7984,0.45693671,19,24,,2.00E-64,Q8CF97,Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135),Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135),GO:0090168; GO:0005795; GO:0005783; GO:0016320; GO:0007067; GO:0035871; GO:0071108; GO:0016567; GO:0006508; GO:0004843,Golgi reassembly; Golgi stack; endoplasmic reticulum; endoplasmic reticulum membrane fusion; mitosis; protein K11-linked deubiquitination; protein K48-linked deubiquitination; protein ubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,VCIP1_RAT,Rattus norvegicus (Rat),endoplasmic reticulum membrane fusion [GO:0016320]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; mitotic nuclear division [GO:0007067]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567] comp134261_c2_seq1,282,41.4894,0.66393797,4,3,,,,,,,,,2.00E-19,CHOYP_LOC752042.1.1,,,,,,,,, comp134261_c3_seq2,2057,47.6908,0.52807423,65,63,,2.00E-51,Q8CDG3,Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135),Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135),GO:0090168; GO:0005795; GO:0005783; GO:0016320; GO:0007067; GO:0035871; GO:0071108; GO:0016567; GO:0006508; GO:0004843,Golgi reassembly; Golgi stack; endoplasmic reticulum; endoplasmic reticulum membrane fusion; mitosis; protein K11-linked deubiquitination; protein K48-linked deubiquitination; protein ubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,VCIP1_MOUSE,Mus musculus (Mouse),protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567] comp134262_c0_seq1,814,39.312,0.61448505,0,0,,3.00E-23,P61908,Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase),Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase),GO:0006226; GO:0004170; GO:0046080; GO:0000287,dUMP biosynthetic process; dUTP diphosphatase activity; dUTP metabolic process; magnesium ion binding,PF00692;,,,,,,,,,DUT_GEOSL,Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA),dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081] comp134262_c0_seq2,1018,42.7308,0.76282317,0,24,,2.00E-55,Q89662,Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase),Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase),GO:0006226; GO:0004170; GO:0046080; GO:0046872,dUMP biosynthetic process; dUTP diphosphatase activity; dUTP metabolic process; metal ion binding,PF00692;,3.00E-49,CHOYP_LOC100183847.2.2,,,,,,,DUT_ADEG1,Fowl adenovirus A serotype 1 (strain CELO / Phelps) (FAdV-1) (Avian adenovirus gal1 (strain Phelps)),dUMP biosynthetic process [GO:0006226]; dUTP metabolic process [GO:0046080] comp134262_c0_seq3,979,41.9816,0.72811887,23,22,,7.00E-70,P33316,"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)","Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)",GO:0006260; GO:0006226; GO:0004170; GO:0046080; GO:0005739; GO:0005654; GO:0006206; GO:0046134,DNA replication; dUMP biosynthetic process; dUTP diphosphatase activity; dUTP metabolic process; mitochondrion; nucleoplasm; pyrimidine nucleobase metabolic process; pyrimidine nucleoside biosynthetic process,PF00692;,,,,,,,,,DUT_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside biosynthetic process [GO:0046134] comp134262_c0_seq4,853,40.211,0.64898189,0,0,,1.00E-14,Q16AZ3,Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase),Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase),GO:0006226; GO:0004170; GO:0046080; GO:0000287,dUMP biosynthetic process; dUTP diphosphatase activity; dUTP metabolic process; magnesium ion binding,PF00692;,2.00E-36,CHOYP_LOC100557203.1.1,,,,,,,DUT_ROSDO,Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans),dUMP biosynthetic process [GO:0006226]; dUTP metabolic process [GO:0046080] comp134266_c0_seq1,1706,39.9766,0.34144465,49,63,,5.00E-110,Q5ZIF1,Adipocyte plasma membrane-associated protein,Adipocyte plasma membrane-associated protein,GO:0004064; GO:0009058; GO:0009986; GO:0016021; GO:0016844,arylesterase activity; biosynthetic process; cell surface; integral to membrane; strictosidine synthase activity,PF03088;,2.00E-34,CHOYP_APMAP.1.1,,,,,,,APMAP_CHICK,Gallus gallus (Chicken),biosynthetic process [GO:0009058] comp134267_c0_seq1,6354,35.0331,0.65373988,0,0,,4.00E-126,Q92630,Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0042771; GO:0000287; GO:0030145; GO:0051534; GO:0005634; GO:0045725; GO:0004674; GO:0004712; GO:0004713; GO:0030529; GO:0007224; GO:0043130; GO:0000151,ATP binding; cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; magnesium ion binding; manganese ion binding; negative regulation of NFAT protein import into nucleus; nucleus; positive regulation of glycogen biosynthetic process; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; ribonucleoprotein complex; smoothened signaling pathway; ubiquitin binding; ubiquitin ligase complex,PF00069;,6.00E-174,CHOYP_EF1A.4.4,,,,,,,DYRK2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224] comp134267_c0_seq2,2844,38.2208,0.70373077,0,0,,4.00E-122,Q5ZIU3,Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0042771; GO:0000287; GO:0030145; GO:0051534; GO:0005634; GO:0045725; GO:0004674; GO:0004712; GO:0004713; GO:0030529; GO:0007224; GO:0000151,ATP binding; cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; magnesium ion binding; manganese ion binding; negative regulation of NFAT protein import into nucleus; nucleus; positive regulation of glycogen biosynthetic process; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; ribonucleoprotein complex; smoothened signaling pathway; ubiquitin ligase complex,PF00069;,,,,,,,,,DYRK2_CHICK,Gallus gallus (Chicken),intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; smoothened signaling pathway [GO:0007224] comp134267_c0_seq3,5837,35.4634,0.72885207,0,0,,9.00E-116,O08605,MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1),MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1),GO:0005524; GO:0097192; GO:0007243; GO:0018105; GO:0004674; GO:0006417; GO:0009651,ATP binding; extrinsic apoptotic signaling pathway in absence of ligand; intracellular protein kinase cascade; peptidyl-serine phosphorylation; protein serine/threonine kinase activity; regulation of translation; response to salt stress,PF00069;,1.00E-99,CHOYP_PCDH9.4.5,,,,,,,MKNK1_MOUSE,Mus musculus (Mouse),extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; response to salt stress [GO:0009651] comp134267_c0_seq4,3108,37.8057,0.73121088,0,0,,2.00E-22,Q8SR86,Cyclin-dependent kinase 1 (CDK1) (Cell division control protein 28 homolog) (EC 2.7.11.22) (Cell division protein kinase 1),Cyclin-dependent kinase 1 (CDK1) (Cell division control protein 28 homolog) (EC 2.7.11.22) (Cell division protein kinase 1),GO:0005524; GO:0051301; GO:0004693; GO:0007067; GO:0005634,ATP binding; cell division; cyclin-dependent protein serine/threonine kinase activity; mitosis; nucleus,PF00069;,,,,,,,,,CDK1_ENCCU,Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp134267_c0_seq5,3361,36.983,0.58357476,171,2,,0,Q92630,Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0042771; GO:0000287; GO:0030145; GO:0051534; GO:0005634; GO:0045725; GO:0004674; GO:0004712; GO:0004713; GO:0030529; GO:0007224; GO:0043130; GO:0000151,ATP binding; cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; magnesium ion binding; manganese ion binding; negative regulation of NFAT protein import into nucleus; nucleus; positive regulation of glycogen biosynthetic process; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; ribonucleoprotein complex; smoothened signaling pathway; ubiquitin binding; ubiquitin ligase complex,PF00069;,0,CHOYP_EF1A.4.4,,,3.00E-122,AM864416.p.cg.6,7,,DYRK2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224] comp134267_c0_seq6,6101,35.3713,0.74440574,0,0,,1.00E-115,O08605,MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1),MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1),GO:0005524; GO:0097192; GO:0007243; GO:0018105; GO:0004674; GO:0006417; GO:0009651,ATP binding; extrinsic apoptotic signaling pathway in absence of ligand; intracellular protein kinase cascade; peptidyl-serine phosphorylation; protein serine/threonine kinase activity; regulation of translation; response to salt stress,PF00069;,1.00E-99,CHOYP_PCDH9.4.5,,,,,,,MKNK1_MOUSE,Mus musculus (Mouse),extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; response to salt stress [GO:0009651] comp134269_c0_seq2,575,38.9565,0.23378592,41,98,,5.00E-14,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp134272_c0_seq2,2186,44.3733,0.51251417,0,15,,3.00E-55,P18850,Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha],Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha],GO:0000139; GO:0006987; GO:0005789; GO:0016021; GO:0005635; GO:0005654; GO:0006990; GO:0006457; GO:0043565; GO:0003700; GO:0003713; GO:0006351,"Golgi membrane; activation of signaling protein activity involved in unfolded protein response; endoplasmic reticulum membrane; integral to membrane; nuclear envelope; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; protein folding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription, DNA-dependent",PF00170;,5.00E-12,CHOYP_LOC100693055.1.1,,,,,,,ATF6A_HUMAN,Homo sapiens (Human),"ATF6-mediated unfolded protein response [GO:0036500]; endoplasmic reticulum unfolded protein response [GO:0030968]; eye development [GO:0001654]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein folding [GO:0006457]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to stress [GO:0006950]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp134274_c0_seq1,641,35.4134,0.66018196,254,418,,2.00E-43,Q9U2M7,"Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.-) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nudix hydrolase 4)","Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.-) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nudix hydrolase 4)",GO:0043135; GO:0006172; GO:0006167; GO:0005524; GO:0006754; GO:0006915; GO:0004081; GO:0015967,5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity; ADP biosynthetic process; AMP biosynthetic process; ATP binding; ATP biosynthetic process; apoptotic process; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity; diadenosine tetraphosphate catabolic process,PF00293;,1.00E-13,CHOYP_LOC658593.1.1,,,,,,,AP4A_CAEEL,Caenorhabditis elegans,ADP biosynthetic process [GO:0006172]; AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; diadenosine tetraphosphate catabolic process [GO:0015967]; ribose phosphate metabolic process [GO:0019693] comp134276_c0_seq1,1463,37.3889,0.57179825,3335,870,,2.00E-133,Q26630,"33 kDa inner dynein arm light chain, axonemal (p33)","33 kDa inner dynein arm light chain, axonemal (p33)",GO:0030286; GO:0003774,dynein complex; motor activity,PF10211;,0,CHOYP_IDLC.1.1,6.00E-171,ruditapes_c4090,0,AM855501.p.cg.6,5,,IDLC_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp134278_c0_seq1,2542,42.8009,0.47263353,0,0,,3.00E-135,Q90600,Retinoblastoma-associated protein (p104) (pRb) (Rb),Retinoblastoma-associated protein (p104) (pRb) (Rb),GO:0003677; GO:0007049; GO:0016568; GO:0019048; GO:0005634; GO:0051726; GO:0006357; GO:0006351,"DNA binding; cell cycle; chromatin modification; modulation by virus of host morphology or physiology; nucleus; regulation of cell cycle; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF11934;PF01858;PF01857;PF08934;,,,,,,,,,RB_CHICK,Gallus gallus (Chicken),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chromatin modification [GO:0016568]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp134278_c0_seq2,2898,42.029,0.46903699,35,41,,6.00E-140,Q90600,Retinoblastoma-associated protein (p104) (pRb) (Rb),Retinoblastoma-associated protein (p104) (pRb) (Rb),GO:0003677; GO:0007049; GO:0016568; GO:0019048; GO:0005634; GO:0051726; GO:0006357; GO:0006351,"DNA binding; cell cycle; chromatin modification; modulation by virus of host morphology or physiology; nucleus; regulation of cell cycle; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF11934;PF01858;PF01857;PF08934;,,,,,,,,,RB_CHICK,Gallus gallus (Chicken),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chromatin modification [GO:0016568]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp134278_c0_seq3,1486,42.3957,0.4052141,0,0,,,,,,,,,6.00E-34,CHOYP_RB.1.1,,,,,,,,, comp134280_c1_seq1,1837,44.3658,0.75336972,63,429,,1.00E-59,Q28619,Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1),Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1),GO:0016055; GO:0016324; GO:0032782; GO:0017081; GO:0005737; GO:0012505; GO:0030175; GO:0034635; GO:0031528; GO:2000146; GO:0014067; GO:0010642; GO:0051898; GO:0045859; GO:0097291; GO:0001726; GO:0097225,Wnt receptor signaling pathway; apical plasma membrane; bile acid secretion; chloride channel regulator activity; cytoplasm; endomembrane system; filopodium; glutathione transport; microvillus membrane; negative regulation of cell motility; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of platelet-derived growth factor receptor signaling pathway; negative regulation of protein kinase B signaling cascade; regulation of protein kinase activity; renal phosphate ion absorption; ruffle; sperm midpiece,PF09007;PF00595;,1.00E-24,CHOYP_BRAFLDRAFT_120990.18.18,,,,,,,NHRF1_RABIT,Oryctolagus cuniculus (Rabbit),bile acid secretion [GO:0032782]; glutathione transport [GO:0034635]; negative regulation of cell motility [GO:2000146]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; regulation of protein kinase activity [GO:0045859]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; Wnt signaling pathway [GO:0016055] comp134281_c3_seq2,327,44.0367,0.12855303,3,26,,2.00E-17,Q00725,Salivary glue protein Sgs-4,Salivary glue protein Sgs-4,GO:0005576,extracellular region,,,,,,,,,,SGS4_DROME,Drosophila melanogaster (Fruit fly), comp134289_c0_seq1,367,35.9673,0.85442938,17,22,,,,,,,,,3.00E-18,CHOYP_ZN598.1.1,,,,,,,,, comp134289_c1_seq1,1129,43.4012,0.48946311,0,3,,3.00E-33,Q80YR4,Zinc finger protein 598,Zinc finger protein 598,GO:0008270,zinc ion binding,,,,,,,,,,ZN598_MOUSE,Mus musculus (Mouse), comp134289_c1_seq2,1345,43.3457,0.57063482,0,0,,7.00E-28,Q76PD2,LIM domain and RING finger protein C1223.01,E3 ubiquitin-protein ligase hel2 (EC 6.3.2.-) (Histone E3 ligase 2),GO:0005829; GO:0005634; GO:0004842; GO:0008270,cytosol; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,8.00E-32,CHOYP_LOC100119750.1.1,,,,,,,YJ01_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein ubiquitination [GO:0016567] comp134289_c1_seq3,1390,42.9496,0.5628417,3,6,,3.00E-68,Q80YR4,Zinc finger protein 598,Zinc finger protein 598,GO:0008270,zinc ion binding,,,,,,,,,,ZN598_MOUSE,Mus musculus (Mouse), comp134291_c0_seq1,933,34.8339,0.40426583,15,145,,8.00E-44,Q5RDC7,RWD domain-containing protein 3,RWD domain-containing protein 3,GO:0005737; GO:0005634,cytoplasm; nucleus,PF05773;,,,,,,,,,RWDD3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235] comp134295_c1_seq1,748,35.5615,0.55497392,89,441,,,,,,,,,,,8.00E-14,ruditapes_c17805,,,,,,, comp134297_c0_seq1,486,43.4156,0.89194517,0,74,,9.00E-35,P30122,Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),GO:0047372; GO:0004091; GO:0005829; GO:0005615; GO:0016042; GO:0004771; GO:0004806,acylglycerol lipase activity; carboxylesterase activity; cytosol; extracellular space; lipid catabolic process; sterol esterase activity; triglyceride lipase activity,PF00135;,,,,,,,,,CEL_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp134298_c0_seq11,1500,36.4667,0.40162702,0,0,,4.00E-11,P96576,Uncharacterized methyltransferase YdaC (EC 2.1.1.-),Uncharacterized methyltransferase YdaC (EC 2.1.1.-),GO:0008168,methyltransferase activity,,,,,,,,,,YDAC_BACSU,Bacillus subtilis (strain 168), comp134298_c0_seq12,1364,34.8974,0.33742404,0,0,,3.00E-06,Q2YY85,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_STAAB,Staphylococcus aureus (strain bovine RF122 / ET3-1),menaquinone biosynthetic process [GO:0009234] comp134298_c0_seq2,835,39.1617,0.47036827,0,0,,7.00E-12,P96576,Uncharacterized methyltransferase YdaC (EC 2.1.1.-),Uncharacterized methyltransferase YdaC (EC 2.1.1.-),GO:0008168,methyltransferase activity,,,,,,,,,,YDAC_BACSU,Bacillus subtilis (strain 168), comp134298_c0_seq4,1454,36.2448,0.33538885,0,0,,4.00E-06,P67063,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_STAAW,Staphylococcus aureus (strain MW2),menaquinone biosynthetic process [GO:0009234] comp134298_c0_seq6,926,38.3369,0.35833053,0,0,,2.00E-06,A1RP78,"Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)","Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)",GO:0009234; GO:0008168; GO:0006744,menaquinone biosynthetic process; methyltransferase activity; ubiquinone biosynthetic process,PF01209;,,,,,,,,,UBIE_SHESW,Shewanella sp. (strain W3-18-1),aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744] comp134298_c0_seq7,1551,36.4281,0.3695888,0,0,,4.00E-06,A1RP78,"Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)","Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)",GO:0009234; GO:0008168; GO:0006744,menaquinone biosynthetic process; methyltransferase activity; ubiquinone biosynthetic process,PF01209;,,,,,,,,,UBIE_SHESW,Shewanella sp. (strain W3-18-1),aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744] comp134298_c0_seq9,1318,34.9014,0.29929675,0,0,,2.00E-06,Q6GGU0,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_STAAR,Staphylococcus aureus (strain MRSA252),menaquinone biosynthetic process [GO:0009234] comp134303_c0_seq1,954,39.6226,0.56145078,220,3786,,2.00E-91,Q6AY40,JmjC domain-containing protein 8 (Jumonji domain-containing protein 8),JmjC domain-containing protein 8 (Jumonji domain-containing protein 8),,,,2.00E-75,CHOYP_LOC100375791.1.1,,,,,,,JMJD8_RAT,Rattus norvegicus (Rat), comp134309_c0_seq2,720,42.6389,0.96108717,0,9,,,,,,,,,6.00E-11,CHOYP_RFESD.1.1,,,,,,,,, comp134309_c0_seq3,693,42.7128,0.89763675,1,5,,4.00E-31,Q8TAC1,Rieske domain-containing protein,Rieske domain-containing protein,GO:0051537; GO:0046872; GO:0016491,"2 iron, 2 sulfur cluster binding; metal ion binding; oxidoreductase activity",PF00355;,6.00E-11,CHOYP_RFESD.1.1,,,,,,,RFESD_HUMAN,Homo sapiens (Human), comp134312_c1_seq2,1682,31.4507,0.43414845,0,0,,,,,,,,,4.00E-11,CHOYP_contig_037330,,,,,,,,, comp134312_c1_seq4,989,31.9515,0.23828651,0,0,,,,,,,,,,,5.00E-12,ruditapes_c15855,,,,,,, comp134312_c1_seq9,1084,33.2103,0.33553962,17,52,,,,,,,,,3.00E-11,CHOYP_contig_037330,,,,,,,,, comp134317_c0_seq1,1598,41.5519,1.12446274,377,4351,,,,,,,,,,,1.00E-40,ruditapes_c25769,,,,,,, comp134318_c0_seq1,2859,35.8867,0.44902435,1,41,,3.00E-138,Q8BTV1,Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33),Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33),GO:0045454; GO:0050890; GO:0016021; GO:0015095; GO:0005739; GO:0008250; GO:0018279,cell redox homeostasis; cognition; integral to membrane; magnesium ion transmembrane transporter activity; mitochondrion; oligosaccharyltransferase complex; protein N-linked glycosylation via asparagine,PF04756;,,,,,,,,,TUSC3_MOUSE,Mus musculus (Mouse),cognition [GO:0050890]; magnesium ion transport [GO:0015693]; protein N-linked glycosylation via asparagine [GO:0018279] comp134318_c0_seq3,2457,36.4265,0.47087181,0,0,,,,,,,,,2.00E-151,CHOYP_TUSC3.1.1,,,,,,,,, comp134318_c0_seq4,2484,36.3527,0.46798037,0,13,,1.00E-139,Q8BTV1,Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33),Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33),GO:0045454; GO:0050890; GO:0016021; GO:0015095; GO:0005739; GO:0008250; GO:0018279,cell redox homeostasis; cognition; integral to membrane; magnesium ion transmembrane transporter activity; mitochondrion; oligosaccharyltransferase complex; protein N-linked glycosylation via asparagine,PF04756;,,,8.00E-71,ruditapes_c24061,,,,,TUSC3_MOUSE,Mus musculus (Mouse),cognition [GO:0050890]; magnesium ion transport [GO:0015693]; protein N-linked glycosylation via asparagine [GO:0018279] comp134322_c0_seq1,1224,42.3203,0.45721952,12,321,,3.00E-154,Q571E4,N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase),N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase),GO:0043890; GO:0005764; GO:0046872; GO:0008484,N-acetylgalactosamine-6-sulfatase activity; lysosome; metal ion binding; sulfuric ester hydrolase activity,PF00884;,8.00E-76,CHOYP_GALNS.1.1,,,,,,,GALNS_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp134323_c0_seq1,725,43.0345,0.82848847,40,827,,2.00E-31,P05090,Apolipoprotein D (Apo-D) (ApoD),Apolipoprotein D (Apo-D) (ApoD),GO:0007568; GO:0001525; GO:0007420; GO:0015485; GO:0022626; GO:0030425; GO:0005783; GO:0005615; GO:0006006; GO:0006629; GO:0005319; GO:2000405; GO:1900016; GO:0051895; GO:0060588; GO:0071638; GO:0010642; GO:0042308; GO:0048662; GO:2000098; GO:0043025; GO:0048471; GO:0014012; GO:0042493; GO:0000302; GO:0042246,aging; angiogenesis; brain development; cholesterol binding; cytosolic ribosome; dendrite; endoplasmic reticulum; extracellular space; glucose metabolic process; lipid metabolic process; lipid transporter activity; negative regulation of T cell migration; negative regulation of cytokine production involved in inflammatory response; negative regulation of focal adhesion assembly; negative regulation of lipoprotein lipid oxidation; negative regulation of monocyte chemotactic protein-1 production; negative regulation of platelet-derived growth factor receptor signaling pathway; negative regulation of protein import into nucleus; negative regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell-matrix adhesion; neuronal cell body; perinuclear region of cytoplasm; peripheral nervous system axon regeneration; response to drug; response to reactive oxygen species; tissue regeneration,PF08212;,,,2.00E-14,ruditapes2_c2044,,,,,APOD_HUMAN,Homo sapiens (Human),aging [GO:0007568]; angiogenesis [GO:0001525]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246] comp134329_c1_seq1,1440,41.3889,0.8120181,64,113,,7.00E-08,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp134333_c0_seq1,728,41.0714,0.33373072,323,1006,,5.00E-31,Q86KD0,BolA-like protein DDB_G0274169,BolA-like protein DDB_G0274169,,,PF01722;,2.00E-18,CHOYP_LOC100122269.1.1,2.00E-58,ruditapes_c8003,,,,,Y7416_DICDI,Dictyostelium discoideum (Slime mold), comp134335_c0_seq1,861,43.4379,0.51789616,1,5,,3.00E-82,Q96EB6,NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)],NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)],GO:0006260; GO:0000731; GO:0070403; GO:0046969; GO:0016605; GO:0001525; GO:0007569; GO:0001678; GO:0070301; GO:0071456; GO:0071479; GO:0009267; GO:0071356; GO:0035356; GO:0042632; GO:0000183; GO:0005677; GO:0005737; GO:0006343; GO:0055089; GO:0042771; GO:0006344; GO:0046872; GO:0006346; GO:0019048; GO:0007517; GO:0043518; GO:0043124; GO:0032088; GO:0032007; GO:0060766; GO:0043066; GO:2000480; GO:0030308; GO:2000655; GO:2000773; GO:0045599; GO:0051097; GO:1902166; GO:1902176; GO:2000757; GO:0031393; GO:0051898; GO:0000122; GO:0030512; GO:0005719; GO:0005720; GO:0005637; GO:0005730; GO:0001542; GO:0018394; GO:0034983; GO:0045739; GO:0045348; GO:0002821; GO:2000481; GO:0008284; GO:2000774; GO:0010875; GO:0031937; GO:0043280; GO:0046628; GO:0016239; GO:2000111; GO:0045944; GO:0043161; GO:0031648; GO:0016567; GO:0000720; GO:0033553; GO:0006364; GO:0070857; GO:0032071; GO:0010906; GO:0007346; GO:0035358; GO:0033158; GO:0034391; GO:0032868; GO:0000012; GO:0007283; GO:0003714; GO:0006351; GO:0006642; GO:0050872,"DNA replication; DNA synthesis involved in DNA repair; NAD+ binding; NAD-dependent histone deacetylase activity (H3-K9 specific); PML body; angiogenesis; cell aging; cellular glucose homeostasis; cellular response to hydrogen peroxide; cellular response to hypoxia; cellular response to ionizing radiation; cellular response to starvation; cellular response to tumor necrosis factor; cellular triglyceride homeostasis; cholesterol homeostasis; chromatin silencing at rDNA; chromatin silencing complex; cytoplasm; establishment of chromatin silencing; fatty acid homeostasis; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; maintenance of chromatin silencing; metal ion binding; methylation-dependent chromatin silencing; modulation by virus of host morphology or physiology; muscle organ development; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB transcription factor activity; negative regulation of TOR signaling cascade; negative regulation of androgen receptor signaling pathway; negative regulation of apoptotic process; negative regulation of cAMP-dependent protein kinase activity; negative regulation of cell growth; negative regulation of cellular response to testosterone stimulus; negative regulation of cellular senescence; negative regulation of fat cell differentiation; negative regulation of helicase activity; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of peptidyl-lysine acetylation; negative regulation of prostaglandin biosynthetic process; negative regulation of protein kinase B signaling cascade; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; nuclear euchromatin; nuclear heterochromatin; nuclear inner membrane; nucleolus; ovulation from ovarian follicle; peptidyl-lysine acetylation; peptidyl-lysine deacetylation; positive regulation of DNA repair; positive regulation of MHC class II biosynthetic process; positive regulation of adaptive immune response; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cell proliferation; positive regulation of cellular senescence; positive regulation of cholesterol efflux; positive regulation of chromatin silencing; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of insulin receptor signaling pathway; positive regulation of macroautophagy; positive regulation of macrophage apoptotic process; positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; protein destabilization; protein ubiquitination; pyrimidine dimer repair by nucleotide-excision repair; rDNA heterochromatin; rRNA processing; regulation of bile acid biosynthetic process; regulation of endodeoxyribonuclease activity; regulation of glucose metabolic process; regulation of mitotic cell cycle; regulation of peroxisome proliferator activated receptor signaling pathway; regulation of protein import into nucleus, translocation; regulation of smooth muscle cell apoptotic process; response to insulin stimulus; single strand break repair; spermatogenesis; transcription corepressor activity; transcription, DNA-dependent; triglyceride mobilization; white fat cell differentiation",PF02146;,,,,,,,,,SIR1_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein import into nucleus, translocation [GO:0033158]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; rRNA processing [GO:0006364]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transcription, DNA-templated [GO:0006351]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]" comp134335_c0_seq2,1300,46.2308,0.5623424,12,17,,4.00E-154,Q96EB6,NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)],NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)],GO:0006260; GO:0000731; GO:0070403; GO:0046969; GO:0016605; GO:0001525; GO:0007569; GO:0001678; GO:0070301; GO:0071456; GO:0071479; GO:0009267; GO:0071356; GO:0035356; GO:0042632; GO:0000183; GO:0005677; GO:0005737; GO:0006343; GO:0055089; GO:0042771; GO:0006344; GO:0046872; GO:0006346; GO:0019048; GO:0007517; GO:0043518; GO:0043124; GO:0032088; GO:0032007; GO:0060766; GO:0043066; GO:2000480; GO:0030308; GO:2000655; GO:2000773; GO:0045599; GO:0051097; GO:1902166; GO:1902176; GO:2000757; GO:0031393; GO:0051898; GO:0000122; GO:0030512; GO:0005719; GO:0005720; GO:0005637; GO:0005730; GO:0001542; GO:0018394; GO:0034983; GO:0045739; GO:0045348; GO:0002821; GO:2000481; GO:0008284; GO:2000774; GO:0010875; GO:0031937; GO:0043280; GO:0046628; GO:0016239; GO:2000111; GO:0045944; GO:0043161; GO:0031648; GO:0016567; GO:0000720; GO:0033553; GO:0006364; GO:0070857; GO:0032071; GO:0010906; GO:0007346; GO:0035358; GO:0033158; GO:0034391; GO:0032868; GO:0000012; GO:0007283; GO:0003714; GO:0006351; GO:0006642; GO:0050872,"DNA replication; DNA synthesis involved in DNA repair; NAD+ binding; NAD-dependent histone deacetylase activity (H3-K9 specific); PML body; angiogenesis; cell aging; cellular glucose homeostasis; cellular response to hydrogen peroxide; cellular response to hypoxia; cellular response to ionizing radiation; cellular response to starvation; cellular response to tumor necrosis factor; cellular triglyceride homeostasis; cholesterol homeostasis; chromatin silencing at rDNA; chromatin silencing complex; cytoplasm; establishment of chromatin silencing; fatty acid homeostasis; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; maintenance of chromatin silencing; metal ion binding; methylation-dependent chromatin silencing; modulation by virus of host morphology or physiology; muscle organ development; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB transcription factor activity; negative regulation of TOR signaling cascade; negative regulation of androgen receptor signaling pathway; negative regulation of apoptotic process; negative regulation of cAMP-dependent protein kinase activity; negative regulation of cell growth; negative regulation of cellular response to testosterone stimulus; negative regulation of cellular senescence; negative regulation of fat cell differentiation; negative regulation of helicase activity; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of peptidyl-lysine acetylation; negative regulation of prostaglandin biosynthetic process; negative regulation of protein kinase B signaling cascade; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; nuclear euchromatin; nuclear heterochromatin; nuclear inner membrane; nucleolus; ovulation from ovarian follicle; peptidyl-lysine acetylation; peptidyl-lysine deacetylation; positive regulation of DNA repair; positive regulation of MHC class II biosynthetic process; positive regulation of adaptive immune response; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cell proliferation; positive regulation of cellular senescence; positive regulation of cholesterol efflux; positive regulation of chromatin silencing; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of insulin receptor signaling pathway; positive regulation of macroautophagy; positive regulation of macrophage apoptotic process; positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; protein destabilization; protein ubiquitination; pyrimidine dimer repair by nucleotide-excision repair; rDNA heterochromatin; rRNA processing; regulation of bile acid biosynthetic process; regulation of endodeoxyribonuclease activity; regulation of glucose metabolic process; regulation of mitotic cell cycle; regulation of peroxisome proliferator activated receptor signaling pathway; regulation of protein import into nucleus, translocation; regulation of smooth muscle cell apoptotic process; response to insulin stimulus; single strand break repair; spermatogenesis; transcription corepressor activity; transcription, DNA-dependent; triglyceride mobilization; white fat cell differentiation",PF02146;,6.00E-84,CHOYP_SIRT1.1.1,,,,,,,SIR1_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein import into nucleus, translocation [GO:0033158]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; rRNA processing [GO:0006364]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transcription, DNA-templated [GO:0006351]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]" comp134341_c0_seq2,1720,38.1395,0.36793,0,0,,8.00E-25,Q6PAF4,Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-),Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-),GO:0006310; GO:0006281; GO:0030915; GO:0000781; GO:0046872; GO:0005634; GO:2001022; GO:0004842,"DNA recombination; DNA repair; Smc5-Smc6 complex; chromosome, telomeric region; metal ion binding; nucleus; positive regulation of response to DNA damage stimulus; ubiquitin-protein ligase activity",PF07574;PF08746;,,,,,,,,,NSE1_XENLA,Xenopus laevis (African clawed frog),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of response to DNA damage stimulus [GO:2001022] comp134341_c0_seq3,1698,38.3392,0.36882505,0,0,,4.00E-23,Q3T0X7,Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-),Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-),GO:0006310; GO:0006281; GO:0030915; GO:0000781; GO:0035556; GO:0005634; GO:2001022; GO:0004842; GO:0008270,"DNA recombination; DNA repair; Smc5-Smc6 complex; chromosome, telomeric region; intracellular signal transduction; nucleus; positive regulation of response to DNA damage stimulus; ubiquitin-protein ligase activity; zinc ion binding",PF07574;PF08746;,,,,,,,,,NSE1_BOVIN,Bos taurus (Bovine),double-strand break repair via homologous recombination [GO:0000724]; intracellular signal transduction [GO:0035556]; positive regulation of response to DNA damage stimulus [GO:2001022]; postreplication repair [GO:0006301]; protein ubiquitination [GO:0016567] comp134341_c0_seq8,1593,38.4809,0.37341356,0,0,,5.00E-25,Q6PAF4,Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-),Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-),GO:0006310; GO:0006281; GO:0030915; GO:0000781; GO:0046872; GO:0005634; GO:2001022; GO:0004842,"DNA recombination; DNA repair; Smc5-Smc6 complex; chromosome, telomeric region; metal ion binding; nucleus; positive regulation of response to DNA damage stimulus; ubiquitin-protein ligase activity",PF07574;PF08746;,,,,,,,,,NSE1_XENLA,Xenopus laevis (African clawed frog),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of response to DNA damage stimulus [GO:2001022] comp134342_c0_seq1,704,43.608,0.83978728,34,259,,4.00E-28,P97864,"Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11; Caspase-7, N-terminally processed]",Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11],GO:0004190; GO:0097153; GO:0005737; GO:0097194; GO:0007507; GO:0005634; GO:0043525; GO:0016485; GO:0006508; GO:0001836; GO:0009411,aspartic-type endopeptidase activity; cysteine-type endopeptidase activity involved in apoptotic process; cytoplasm; execution phase of apoptosis; heart development; nucleus; positive regulation of neuron apoptotic process; protein processing; proteolysis; release of cytochrome c from mitochondria; response to UV,,,,,,,,,,CASP7_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; heart development [GO:0007507]; neuron apoptotic process [GO:0051402]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411] comp134348_c0_seq2,823,49.2102,0.41185646,2,0,,6.00E-31,Q6AYJ2,Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B),Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B),GO:0051301; GO:0000777; GO:0005737; GO:0005815; GO:0007067,cell division; condensed chromosome kinetochore; cytoplasm; microtubule organizing center; mitosis,,8.00E-36,CHOYP_LOC100373080.6.6,,,,,,,BOD1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp134348_c1_seq2,3335,42.1889,0.47662789,1,1,,,,,,,,,2.00E-26,CHOYP_LOC100373080.6.6,,,,,,,,, comp134351_c0_seq1,1049,34.1277,0.65746279,115,767,,3.00E-26,P49962,Signal recognition particle 9 kDa protein (SRP9),Signal recognition particle 9 kDa protein (SRP9),GO:0008312; GO:0006614; GO:0045900; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; negative regulation of translational elongation; signal recognition particle, endoplasmic reticulum targeting",,3.00E-48,CHOYP_NDUFB9.2.2,,,,,,,SRP09_MOUSE,Mus musculus (Mouse),"negative regulation of translational elongation [GO:0045900]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]" comp134352_c0_seq1,2093,36.4071,0.27928434,53,49,,3.00E-16,Q95LB0,Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),GO:0007597; GO:0009986; GO:0042627; GO:0031012; GO:0008201; GO:0034364; GO:0060230; GO:0016525; GO:0030195; GO:0010596; GO:0001937; GO:0051918; GO:0033033; GO:0034392; GO:0005543; GO:0031639; GO:0051006; GO:0006641; GO:0034361,"blood coagulation, intrinsic pathway; cell surface; chylomicron; extracellular matrix; heparin binding; high-density lipoprotein particle; lipoprotein lipase activator activity; negative regulation of angiogenesis; negative regulation of blood coagulation; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; negative regulation of fibrinolysis; negative regulation of myeloid cell apoptotic process; negative regulation of smooth muscle cell apoptotic process; phospholipid binding; plasminogen activation; positive regulation of lipoprotein lipase activity; triglyceride metabolic process; very-low-density lipoprotein particle",PF00084;PF09014;,,,,,,,,,APOH_PANTR,Pan troglodytes (Chimpanzee),"blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]" comp134353_c0_seq1,1702,45.2409,0.61775134,188,100,,0,Q8NDN9,RCC1 and BTB domain-containing protein 1 (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein) (Regulator of chromosome condensation and BTB domain-containing protein 1),RCC1 and BTB domain-containing protein 1 (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein) (Regulator of chromosome condensation and BTB domain-containing protein 1),GO:0007049; GO:0016568; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"cell cycle; chromatin modification; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00415;,0,CHOYP_BRAFLDRAFT_119547.1.1,,,,,,,RCBT1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134358_c0_seq1,3054,40.9627,0.34370257,268,489,,0,O61585,Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),GO:0051301; GO:0008352; GO:0005874; GO:0051013; GO:0007067; GO:0000922,cell division; katanin complex; microtubule; microtubule severing; mitosis; spindle pole,PF13925;PF00400;,5.00E-96,CHOYP_BRAFLDRAFT_128944.2.2,,,,,,,KTNB1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cell division [GO:0051301]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067] comp134362_c1_seq1,711,46.4135,0.52399279,0,0,,,,,,,,,3.00E-14,CHOYP_LOC100892044.2.2,,,,,,,,, comp134362_c1_seq2,1053,48.2431,0.44134655,4,0,,,,,,,,,1.00E-15,CHOYP_BRAFLDRAFT_131977.1.4,,,,,,,,, comp134369_c1_seq2,1504,42.4867,0.35447228,0,12,,5.00E-82,Q75WF2,Plancitoxin-1 (EC 3.1.22.1) (Plancitoxin I) (Plan-I) [Cleaved into: Plancitoxin-1 subunit alpha; Plancitoxin-1 subunit beta],Plancitoxin-1 (EC 3.1.22.1) (Plancitoxin I) (Plan-I) [Cleaved into: Plancitoxin-1 subunit alpha; Plancitoxin-1 subunit beta],GO:0006259; GO:0006915; GO:0004531; GO:0005576; GO:0090305,DNA metabolic process; apoptotic process; deoxyribonuclease II activity; extracellular region; nucleic acid phosphodiester bond hydrolysis,PF03265;,,,,,,,,,DNA2_ACAPL,Acanthaster planci (Crown-of-thorns starfish),apoptotic process [GO:0006915] comp134369_c1_seq3,910,40.989,0.31529803,0,0,,3.00E-25,Q9QZK9,Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD),Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD),GO:0006259; GO:0004531; GO:0005764,DNA metabolic process; deoxyribonuclease II activity; lysosome,PF03265;,,,,,,,,,DNS2B_RAT,Rattus norvegicus (Rat),apoptotic DNA fragmentation [GO:0006309] comp134369_c1_seq5,904,42.8097,0.24597769,0,0,,7.00E-42,Q75WF2,Plancitoxin-1 (EC 3.1.22.1) (Plancitoxin I) (Plan-I) [Cleaved into: Plancitoxin-1 subunit alpha; Plancitoxin-1 subunit beta],Plancitoxin-1 (EC 3.1.22.1) (Plancitoxin I) (Plan-I) [Cleaved into: Plancitoxin-1 subunit alpha; Plancitoxin-1 subunit beta],GO:0006259; GO:0006915; GO:0004531; GO:0005576; GO:0090305,DNA metabolic process; apoptotic process; deoxyribonuclease II activity; extracellular region; nucleic acid phosphodiester bond hydrolysis,PF03265;,,,,,,,,,DNA2_ACAPL,Acanthaster planci (Crown-of-thorns starfish),apoptotic process [GO:0006915] comp134372_c0_seq1,294,40.1361,0.47874621,14,29,,1.00E-11,Q8N5Y2,Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1),Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1),GO:0003677; GO:0072487; GO:0043984; GO:0035064; GO:0007275; GO:0003700; GO:0006366,DNA binding; MSL complex; histone H4-K16 acetylation; methylated histone residue binding; multicellular organismal development; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,PF05712;PF11717;,1.00E-40,CHOYP_MO4L1.1.1,,,,,,,MS3L1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; chromatin silencing [GO:0006342]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4-K16 acetylation [GO:0043984]; transcription, DNA-templated [GO:0006351]" comp134372_c1_seq1,1126,39.9645,0.46753361,126,191,,1.00E-86,Q6AYU1,Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15),Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15),GO:0035267; GO:0016580; GO:0008283; GO:0003682; GO:0000724; GO:0043968; GO:0043967; GO:0016575; GO:0040008; GO:0006355; GO:0006351,"NuA4 histone acetyltransferase complex; Sin3 complex; cell proliferation; chromatin binding; double-strand break repair via homologous recombination; histone H2A acetylation; histone H4 acetylation; histone deacetylation; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05712;PF11717;,,,,,,,,,MO4L1_RAT,Rattus norvegicus (Rat),"cell proliferation [GO:0008283]; chromatin remodeling [GO:0006338]; chromatin silencing [GO:0006342]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp134374_c0_seq2,1070,41.028,0.53449828,10,15,,6.00E-44,Q7SXN5,Dynamin-1-like protein (EC 3.6.5.5),Dynamin-1-like protein (EC 3.6.5.5),GO:0005525; GO:0003924; GO:0005829; GO:0003374; GO:0016020; GO:0000266; GO:0005739; GO:0005777; GO:0042803,GTP binding; GTPase activity; cytosol; dynamin polymerization involved in mitochondrial fission; membrane; mitochondrial fission; mitochondrion; peroxisome; protein homodimerization activity,PF01031;PF00350;PF02212;,1.00E-35,CHOYP_LOC100646574.1.1,,,,,,,DNM1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),dynamin polymerization involved in mitochondrial fission [GO:0003374]; mitochondrial fission [GO:0000266]; peroxisome fission [GO:0016559] comp134374_c0_seq4,849,37.4558,0.5400905,0,0,,1.00E-15,Q9UQ16,"Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)","Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)",GO:0005525; GO:0003924; GO:0043197; GO:0006897; GO:0046847; GO:0005874; GO:0005739; GO:0048471; GO:0005543; GO:0014069; GO:0007416,GTP binding; GTPase activity; dendritic spine; endocytosis; filopodium assembly; microtubule; mitochondrion; perinuclear region of cytoplasm; phospholipid binding; postsynaptic density; synapse assembly,PF01031;PF00350;PF02212;PF00169;,8.00E-36,CHOYP_LOC100646574.1.1,,,,,,,DYN3_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; filopodium assembly [GO:0046847]; negative regulation of dendritic spine morphogenesis [GO:0061002]; positive regulation of filopodium assembly [GO:0051491]; synapse assembly [GO:0007416] comp134381_c0_seq3,304,39.1447,0.43103915,10,30,,,,,,,,,2.00E-11,CHOYP_contig_037248,,,,,,,,, comp134383_c0_seq2,1233,37.8751,0.33583475,259,2194,,8.00E-64,Q6TNS2,p21-activated protein kinase-interacting protein 1-like (PAK1-interacting protein 1-like),p21-activated protein kinase-interacting protein 1-like (PAK1-interacting protein 1-like),GO:0009968; GO:0005730,negative regulation of signal transduction; nucleolus,PF12894;PF00400;,,,,,,,,,PK1IP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of signal transduction [GO:0009968] comp134386_c1_seq1,2115,42.9787,0.55142653,0,0,,2.00E-145,Q8NB78,Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2),Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2),GO:0003677; GO:0043046; GO:0050660; GO:0034648; GO:0034649; GO:0007275; GO:0005634; GO:0016491; GO:0044030; GO:0006349; GO:0006355; GO:0006351; GO:0008270,"DNA binding; DNA methylation involved in gamete generation; flavin adenine dinucleotide binding; histone demethylase activity (H3-dimethyl-K4 specific); histone demethylase activity (H3-monomethyl-K4 specific); multicellular organismal development; nucleus; oxidoreductase activity; regulation of DNA methylation; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01593;PF04433;PF07496;,,,,,,,,,KDM1B_HUMAN,Homo sapiens (Human),"DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; multicellular organism development [GO:0007275]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134386_c1_seq3,1103,43.3364,0.48990934,0,3,,1.00E-09,Q9Y802,Lysine-specific histone demethylase 1 (EC 1.-.-.-),Lysine-specific histone demethylase 1 (EC 1.-.-.-),GO:0003677; GO:0033193; GO:0009300; GO:0034605; GO:0006338; GO:0032454; GO:0034649; GO:0000790; GO:0016491; GO:0045893; GO:0040020,"DNA binding; Lsd1/2 complex; antisense RNA transcription; cellular response to heat; chromatin remodeling; histone demethylase activity (H3-K9 specific); histone demethylase activity (H3-monomethyl-K4 specific); nuclear chromatin; oxidoreductase activity; positive regulation of transcription, DNA-dependent; regulation of meiosis",PF01593;PF04433;,,,,,,,,,LSD1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"antisense RNA transcription [GO:0009300]; chromatin remodeling [GO:0006338]; genetic imprinting at mating-type locus [GO:0071515]; histone H3-K9 demethylation [GO:0033169]; regulation of meiotic cell cycle [GO:0051445]; regulation of replication fork arrest at rDNA repeats [GO:1902681]; regulation of transcription, DNA-templated [GO:0006355]; replication fork arrest at mating type locus [GO:0011000]" comp134386_c1_seq5,1880,42.6064,0.53693781,0,3,,3.00E-81,Q21988,Amine oxidase family member 1,Amine oxidase family member 1,GO:0003677; GO:0034648; GO:0016491,DNA binding; histone demethylase activity (H3-dimethyl-K4 specific); oxidoreductase activity,PF01593;,,,,,,,,,AMX1_CAEEL,Caenorhabditis elegans,histone H3-K4 demethylation [GO:0034720] comp134386_c1_seq6,2549,42.8796,0.58013197,0,0,,0,Q8NB78,Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2),Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2),GO:0003677; GO:0043046; GO:0050660; GO:0034648; GO:0034649; GO:0007275; GO:0005634; GO:0016491; GO:0044030; GO:0006349; GO:0006355; GO:0006351; GO:0008270,"DNA binding; DNA methylation involved in gamete generation; flavin adenine dinucleotide binding; histone demethylase activity (H3-dimethyl-K4 specific); histone demethylase activity (H3-monomethyl-K4 specific); multicellular organismal development; nucleus; oxidoreductase activity; regulation of DNA methylation; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01593;PF04433;PF07496;,,,,,,,,,KDM1B_HUMAN,Homo sapiens (Human),"DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; multicellular organism development [GO:0007275]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134387_c0_seq1,902,38.1375,0.76567046,4562,39602,,6.00E-80,Q08013,Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma),Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma),GO:0005784; GO:0006613; GO:0030176,Sec61 translocon complex; cotranslational protein targeting to membrane; integral to endoplasmic reticulum membrane,PF07074;,5.00E-96,CHOYP_ISCW_ISCW008596.1.2,5.00E-163,ruditapes_c3399,1.00E-97,CU996024.p.cg.6,9,,SSRG_RAT,Rattus norvegicus (Rat),SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp134394_c2_seq2,1132,46.0247,0.79061439,73,111,,4.00E-25,Q96T23,Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),GO:0034080; GO:0006352; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0005654; GO:0016584; GO:0045893; GO:0050434; GO:0008270,"CENP-A containing nucleosome assembly at centromere; DNA-dependent transcription, initiation; RSF complex; histone binding; negative regulation of DNA binding; negative regulation of transcription, DNA-dependent; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; positive regulation of viral transcription; zinc ion binding",PF00628;PF15612;,4.00E-22,CHOYP_SI_DKEY-21N12.1.1.1,,,,,,,RSF1_HUMAN,Homo sapiens (Human),"CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]" comp134395_c0_seq4,256,44.5312,0.16224995,3,3,,6.00E-08,P71359,ATP-dependent DNA helicase RecQ (EC 3.6.4.12),ATP-dependent DNA helicase RecQ (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009432; GO:0005622,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA binding; DNA recombination; DNA repair; DNA replication; SOS response; intracellular,PF00270;PF00271;PF00570;PF16124;PF09382;,,,,,,,,,RECQ_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] comp134396_c0_seq1,1622,41.6769,0.64907949,227,70,,9.00E-49,D3ZUQ0,RILP-like protein 1 (GAPDH's competitor of SIAH1 protein enhances life) (GOSPEL) (Rab-interacting lysosomal-like protein 1),RILP-like protein 1 (GAPDH's competitor of SIAH1 protein enhances life) (GOSPEL) (Rab-interacting lysosomal-like protein 1),GO:0005813; GO:0005829; GO:0003382; GO:0006886; GO:0005634; GO:0005886; GO:0072372; GO:1901214,centrosome; cytosol; epithelial cell morphogenesis; intracellular protein transport; nucleus; plasma membrane; primary cilium; regulation of neuron death,PF09744;PF11461;,6.00E-53,CHOYP_RIPL1.1.1,,,,,,,RIPL1_RAT,Rattus norvegicus (Rat),epithelial cell morphogenesis [GO:0003382]; protein transport from ciliary membrane to plasma membrane [GO:1903445]; regulation of neuron death [GO:1901214] comp134397_c0_seq1,1380,39.2754,0.27253648,51,405,,2.00E-80,Q8WUA2,Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4),Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4),GO:0003723; GO:0000166; GO:0005634; GO:0003755; GO:0006457; GO:0000413,RNA binding; nucleotide binding; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;PF00076;,1.00E-161,CHOYP_NEMVEDRAFT_V1G96234.1.1,,,,,,,PPIL4_HUMAN,Homo sapiens (Human),protein folding [GO:0006457] comp134397_c0_seq3,1267,38.9897,0.29765277,0,0,,4.00E-78,Q9CXG3,Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4),Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4),GO:0003723; GO:0000166; GO:0005634; GO:0003755; GO:0006457; GO:0000413,RNA binding; nucleotide binding; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;PF00076;,4.00E-54,CHOYP_PPIL4.1.1,3.00E-22,ruditapes_c18348,,,,,PPIL4_MOUSE,Mus musculus (Mouse),protein folding [GO:0006457] comp134398_c2_seq1,878,47.3804,0.28895501,2,0,,2.00E-86,Q29IL2,Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) (Protein twisted),Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) (Protein twisted),GO:0004169; GO:0005783; GO:0005789; GO:0016021; GO:0030259; GO:0097502; GO:0007517; GO:0006493,dolichyl-phosphate-mannose-protein mannosyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; lipid glycosylation; mannosylation; muscle organ development; protein O-linked glycosylation,PF02815;PF02366;PF16192;,1.00E-53,CHOYP_LOC662234.1.1,,,,,,,POMT2_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),lipid glycosylation [GO:0030259]; muscle organ development [GO:0007517] comp134398_c2_seq2,1791,42.7136,0.28490463,41,22,,5.00E-90,Q9UKY4,Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2),Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2),GO:0004169; GO:0005789; GO:0016021; GO:0097502; GO:0046872; GO:0006493,dolichyl-phosphate-mannose-protein mannosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; mannosylation; metal ion binding; protein O-linked glycosylation,PF02815;PF02366;PF16192;,,,,,,,,,POMT2_HUMAN,Homo sapiens (Human),cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101] comp134398_c2_seq3,1607,44.5551,0.27868515,17,25,,5.00E-81,Q9W5D4,Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) (DmPOMT2) (dPOMT2) (Protein twisted),Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) (DmPOMT2) (dPOMT2) (Protein twisted),GO:0004169; GO:0005783; GO:0005789; GO:0016021; GO:0030259; GO:0016203; GO:0035269; GO:0045214; GO:0007525,dolichyl-phosphate-mannose-protein mannosyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; lipid glycosylation; muscle attachment; protein O-linked mannosylation; sarcomere organization; somatic muscle development,PF02815;PF02366;PF16192;,,,,,,,,,POMT2_DROME,Drosophila melanogaster (Fruit fly),cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; lipid glycosylation [GO:0030259]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; protein O-linked mannosylation [GO:0035269]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525] comp134400_c0_seq3,1492,34.1153,0.39963803,20,30,,2.00E-19,P25071,Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3),Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3),GO:0005509; GO:0009506; GO:0009646; GO:0009652; GO:0005774,calcium ion binding; plasmodesma; response to absence of light; thigmotropism; vacuolar membrane,PF13499;,6.00E-116,CHOYP_LOC100313573.1.1,,,,,,,CML12_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to absence of light [GO:0009646]; response to mechanical stimulus [GO:0009612]; thigmotropism [GO:0009652] comp134400_c0_seq4,1531,33.3769,0.40822614,0,0,,4.00E-86,O35648,Centrin-3,Centrin-3,GO:0031683; GO:0005509; GO:0051301; GO:0005814; GO:0045111; GO:0005932; GO:0008017; GO:0007067; GO:0032391,G-protein beta/gamma-subunit complex binding; calcium ion binding; cell division; centriole; intermediate filament cytoskeleton; microtubule basal body; microtubule binding; mitosis; photoreceptor connecting cilium,PF13499;,9.00E-32,CHOYP_CETN1.3.3,4.00E-72,ruditapes_c27296,,,,,CETN3_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp134403_c0_seq2,560,44.4643,0.61969009,6,1,,2.00E-06,Q7Z3T8,Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),GO:0005545; GO:0030509; GO:0031901; GO:0016197; GO:0046872; GO:0005547; GO:0006622; GO:0008565; GO:0030100; GO:0016050,"1-phosphatidylinositol binding; BMP signaling pathway; early endosome membrane; endosomal transport; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; protein targeting to lysosome; protein transporter activity; regulation of endocytosis; vesicle organization",PF11979;PF01363;,,,,,,,,,ZFY16_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050] comp134404_c0_seq1,1606,43.213,1.14778132,15,83,,1.00E-08,P02833,Homeotic protein antennapedia,Homeotic protein antennapedia,GO:0003705; GO:0009948; GO:0005737; GO:0007507; GO:0048542; GO:0007494; GO:0042694; GO:0014019; GO:0005634; GO:0045944; GO:0043565; GO:0007383; GO:0007384,"RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; anterior/posterior axis specification; cytoplasm; heart development; lymph gland development; midgut development; muscle cell fate specification; neuroblast development; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; specification of segmental identity, antennal segment; specification of segmental identity, thorax",PF00046;,,,,,,,,,ANTP_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior axis specification [GO:0009948]; heart development [GO:0007507]; lymph gland development [GO:0048542]; midgut development [GO:0007494]; muscle cell fate specification [GO:0042694]; neuroblast development [GO:0014019]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; specification of segmental identity, antennal segment [GO:0007383]; specification of segmental identity, thorax [GO:0007384]; ventral cord development [GO:0007419]" comp134404_c0_seq2,1184,44.3412,1.08352762,0,0,,2.00E-44,A7MB54,H2.0-like homeobox protein (Homeobox protein HLX1),H2.0-like homeobox protein (Homeobox protein HLX1),GO:0030154; GO:0048557; GO:0048484; GO:0001889; GO:0045629; GO:0005634; GO:0045627; GO:0008284; GO:0046622; GO:0003700; GO:0007519; GO:0000976; GO:0006351,"cell differentiation; embryonic digestive tract morphogenesis; enteric nervous system development; liver development; negative regulation of T-helper 2 cell differentiation; nucleus; positive regulation of T-helper 1 cell differentiation; positive regulation of cell proliferation; positive regulation of organ growth; sequence-specific DNA binding transcription factor activity; skeletal muscle tissue development; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00046;,,,5.00E-25,ruditapes_c11261,,,,,HLX_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp134406_c0_seq1,1280,43.9844,0.56631334,38,261,,7.00E-13,Q6NXM2,RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1),RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1),GO:0007049; GO:0016568; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"cell cycle; chromatin modification; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00415;,,,,,,,,,RCBT1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134406_c1_seq1,569,47.8032,0.55474624,0,0,,6.00E-11,O04316,Nitrile-specifier protein 4 (AtNSP4),Nitrile-specifier protein 4 (AtNSP4) (Jacalin-related lectin 29),GO:0019762; GO:0080028; GO:0009506,glucosinolate catabolic process; nitrile biosynthetic process; plasmodesma,PF01419;PF01344;,,,,,,,,,NSP4_ARATH,Arabidopsis thaliana (Mouse-ear cress),glucosinolate catabolic process [GO:0019762]; nitrile biosynthetic process [GO:0080028] comp134406_c1_seq2,1090,48.5321,0.70733981,21,21,,0,Q8N653,Leucine-zipper-like transcriptional regulator 1 (LZTR-1),Leucine-zipper-like transcriptional regulator 1 (LZTR-1),GO:0009653; GO:0003700,anatomical structure morphogenesis; sequence-specific DNA binding transcription factor activity,PF00651;PF01344;PF07646;,0,CHOYP_LOC100747020.1.1,,,,,,,LZTR1_HUMAN,Homo sapiens (Human),anatomical structure morphogenesis [GO:0009653] comp134409_c0_seq1,553,35.2622,0.67711333,0,4,,5.00E-29,Q2KKX7,Small integral membrane protein 7,Small integral membrane protein 7,GO:0016021,integral to membrane,,2.00E-29,CHOYP_SMIM7.1.2,2.00E-27,ruditapes_c18004,,,,,CS042_SINCH,Siniperca chuatsi (Mandarin fish), comp134409_c0_seq2,577,35.3553,0.68571635,5,33,,,,,,,,,2.00E-28,CHOYP_SMIM7.2.2,,,,,,,,, comp134410_c0_seq1,1199,42.9525,0.38546282,36,149,,,,,,,,,,,5.00E-12,ruditapes_c23562,,,,,,, comp134418_c0_seq1,1882,44.474,0.4529814,112,160,,2.00E-71,Q9DBS8,Centrosomal protein POC5 (Protein of centriole 5),Centrosomal protein POC5 (Protein of centriole 5),GO:0007049; GO:0005814,cell cycle; centriole,,1.00E-44,CHOYP_LOC592888.1.1,4.00E-22,ruditapes_c20041,,,,,POC5_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049] comp134419_c0_seq2,1091,36.9386,0.70343451,271,1234,,2.00E-77,Q9Y399,"28S ribosomal protein S2, mitochondrial (MRP-S2) (S2mt)","28S ribosomal protein S2, mitochondrial (MRP-S2) (S2mt)",GO:0005739; GO:0015935; GO:0003735; GO:0006412,mitochondrion; small ribosomal subunit; structural constituent of ribosome; translation,PF00318;,,,3.00E-33,ruditapes_c11753,,,,,RT02_HUMAN,Homo sapiens (Human),mitochondrial translation [GO:0032543]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; translation [GO:0006412]; xenophagy [GO:0098792] comp134421_c1_seq2,1148,41.115,0.93075027,6,13,,4.00E-42,P00533,Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1),Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1),GO:0005524; GO:0038095; GO:0000139; GO:0004709; GO:0070435; GO:0051015; GO:0043006; GO:0007202; GO:0007411; GO:0016323; GO:0008283; GO:0016337; GO:0071392; GO:0021795; GO:0003682; GO:0048546; GO:0003690; GO:0001892; GO:0030139; GO:0005789; GO:0005768; GO:0010008; GO:0005006; GO:0005615; GO:0008543; GO:0001942; GO:0045087; GO:0016021; GO:0045121; GO:0060571; GO:0043066; GO:0042059; GO:0042177; GO:0048011; GO:0031965; GO:0005634; GO:0001503; GO:0048471; GO:0048015; GO:0045739; GO:0045740; GO:0070374; GO:0043406; GO:0035413; GO:0030335; GO:0031659; GO:0050679; GO:0048146; GO:0045429; GO:0051897; GO:0045944; GO:0046777; GO:0046982; GO:0051205; GO:0004716; GO:0050999; GO:0050730; GO:0070141; GO:0007435,ATP binding; Fc-epsilon receptor signaling pathway; Golgi membrane; MAP kinase kinase kinase activity; Shc-EGFR complex; actin filament binding; activation of phospholipase A2 activity by calcium-mediated signaling; activation of phospholipase C activity; axon guidance; basolateral plasma membrane; cell proliferation; cell-cell adhesion; cellular response to estradiol stimulus; cerebral cortex cell migration; chromatin binding; digestive tract morphogenesis; double-stranded DNA binding; embryonic placenta development; endocytic vesicle; endoplasmic reticulum membrane; endosome; endosome membrane; epidermal growth factor-activated receptor activity; extracellular space; fibroblast growth factor receptor signaling pathway; hair follicle development; innate immune response; integral to membrane; membrane raft; morphogenesis of an epithelial fold; negative regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of protein catabolic process; neurotrophin TRK receptor signaling pathway; nuclear membrane; nucleus; ossification; perinuclear region of cytoplasm; phosphatidylinositol-mediated signaling; positive regulation of DNA repair; positive regulation of DNA replication; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAP kinase activity; positive regulation of catenin import into nucleus; positive regulation of cell migration; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of nitric oxide biosynthetic process; positive regulation of protein kinase B signaling cascade; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; protein heterodimerization activity; protein insertion into membrane; receptor signaling protein tyrosine kinase activity; regulation of nitric-oxide synthase activity; regulation of peptidyl-tyrosine phosphorylation; response to UV-A; salivary gland morphogenesis,PF00757;PF14843;PF07714;PF01030;,,,,,,,,,EGFR_HUMAN,Homo sapiens (Human),activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cerebral cortex cell migration [GO:0021795]; digestive tract morphogenesis [GO:0048546]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein catabolic process [GO:0042177]; ossification [GO:0001503]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to stress [GO:0006950]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337] comp134422_c0_seq1,1060,41.5094,0.46849219,1,48,,,,,,,,,1.00E-52,CHOYP_LOC100704562.1.1,2.00E-22,ruditapes_c31342,,,,,,, comp134422_c0_seq2,1048,41.8893,0.46563137,0,83,,6.00E-95,B7K079,Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase),Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase),GO:0006464; GO:0008113,cellular protein modification process; peptide-methionine (S)-S-oxide reductase activity,PF01625;,,,,,,,,,MSRA_CYAP8,Cyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1)),cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp134432_c0_seq1,1478,44.7903,0.75185815,769,9097,,1.00E-58,P25804,Cysteine proteinase 15A (EC 3.4.22.-) (Turgor-responsive protein 15A),Cysteine proteinase 15A (EC 3.4.22.-) (Turgor-responsive protein 15A),GO:0008234; GO:0006508; GO:0006950,cysteine-type peptidase activity; proteolysis; response to stress,PF08246;PF00112;,3.00E-76,CHOYP_BRAFLDRAFT_77225.1.2,6.00E-76,ruditapes_c7970,,,,,CYSP_PEA,Pisum sativum (Garden pea), comp134434_c1_seq2,2283,36.1805,0.68629821,18,170,,1.00E-24,Q9CQK1,Zinc finger HIT domain-containing protein 3 (Thyroid hormone receptor interactor 3) (Thyroid receptor-interacting protein 3) (TR-interacting protein 3) (TRIP-3),Zinc finger HIT domain-containing protein 3 (Thyroid hormone receptor interactor 3) (Thyroid receptor-interacting protein 3) (TR-interacting protein 3) (TRIP-3),GO:0046872,metal ion binding,PF04438;,,,,,,,,,ZNHI3_MOUSE,Mus musculus (Mouse), comp134436_c0_seq1,1765,36.1473,1.060661,104,4114,,2.00E-27,Q5XHM7,Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2),Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2),GO:0000139; GO:0016051; GO:0047756; GO:0016021,Golgi membrane; carbohydrate biosynthetic process; chondroitin 4-sulfotransferase activity; integral to membrane,PF03567;,,,,,,,,,CHSTC_XENLA,Xenopus laevis (African clawed frog),carbohydrate biosynthetic process [GO:0016051] comp134437_c0_seq1,3203,38.9635,0.79111119,31,44,,0,D3ZSZ3,Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase),Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase),GO:0005524; GO:0004707; GO:0016055; GO:0005737; GO:0000287; GO:0030178; GO:0005634; GO:0018107; GO:0046777; GO:0006355; GO:0033136; GO:0006351; GO:0007179,"ATP binding; MAP kinase activity; Wnt receptor signaling pathway; cytoplasm; magnesium ion binding; negative regulation of Wnt receptor signaling pathway; nucleus; peptidyl-threonine phosphorylation; protein autophosphorylation; regulation of transcription, DNA-dependent; serine phosphorylation of STAT3 protein; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway",PF00069;,0,CHOYP_LOC100313664.1.1,,,,,,,NLK_RAT,Rattus norvegicus (Rat),"negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]; serine phosphorylation of STAT3 protein [GO:0033136]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055]" comp134437_c0_seq3,2674,37.5841,0.77418202,0,4,,6.00E-122,A8XSC1,Serine/threonine kinase NLK (EC 2.7.11.24) (Loss of intestine protein 1) (Nemo-like kinase),Serine/threonine kinase NLK (EC 2.7.11.24) (Loss of intestine protein 1) (Nemo-like kinase),GO:0005524; GO:0004707; GO:0000165; GO:0016055; GO:0005938; GO:0046872; GO:0007275; GO:0005634,ATP binding; MAP kinase activity; MAPK cascade; Wnt receptor signaling pathway; cell cortex; metal ion binding; multicellular organismal development; nucleus,PF00069;,5.00E-152,CHOYP_LOC100313664.1.1,,,,,,,NLK_CAEBR,Caenorhabditis briggsae,multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp134439_c0_seq1,2084,38.1478,1.16610765,4,12,,5.00E-42,Q9VVY3,Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619),Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619),,,PF03370;,,,,,,,,,GBS76_DROME,Drosophila melanogaster (Fruit fly), comp134439_c0_seq2,1967,38.7392,1.16942251,7,12,,3.00E-42,Q9VVY3,Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619),Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619),,,PF03370;,5.00E-30,CHOYP_GBS76.1.1,,,,,,,GBS76_DROME,Drosophila melanogaster (Fruit fly), comp134442_c0_seq1,1037,43.1051,0.58207216,4,0,,2.00E-20,O13728,Alpha-actinin-like protein 1,Alpha-actinin-like protein 1,GO:0051764; GO:0051017; GO:0005826; GO:0005509; GO:0000915; GO:0030674,"actin crosslink formation; actin filament bundle assembly; actomyosin contractile ring; calcium ion binding; cytokinesis, actomyosin contractile ring assembly; protein binding, bridging",PF00307;PF08726;,,,,,,,,,AIN1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; mitotic actomyosin contractile ring assembly [GO:1903475] comp134442_c0_seq2,4569,44.8895,0.63790815,149,141,,0,F1MF74,Protein-methionine sulfoxide oxidase MICAL2 (EC 1.14.13.-) (Molecule interacting with CasL protein 2) (MICAL-2),Protein-methionine sulfoxide oxidase MICAL2 (EC 1.14.13.-) (Molecule interacting with CasL protein 2) (MICAL-2),GO:0071949; GO:0003779; GO:0030042; GO:0005737; GO:0005856; GO:0016709; GO:0019417; GO:0008270,"FAD binding; actin binding; actin filament depolymerization; cytoplasm; cytoskeleton; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; sulfur oxidation; zinc ion binding",PF00307;PF01494;PF00412;,,,4.00E-27,ruditapes_c8765,,,,,MICA2_BOVIN,Bos taurus (Bovine),actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; heart development [GO:0007507]; heart looping [GO:0001947]; oxidation-reduction process [GO:0055114]; positive regulation of transcription via serum response element binding [GO:0010735]; sulfur oxidation [GO:0019417] comp134442_c0_seq3,2849,45.3492,0.67185298,8,0,,0,Q7RTP6,Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),GO:0071949; GO:0003779; GO:0030042; GO:0005737; GO:0005856; GO:0006887; GO:0016709; GO:0008270,"FAD binding; actin binding; actin filament depolymerization; cytoplasm; cytoskeleton; exocytosis; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; zinc ion binding",PF00307;PF12130;PF01494;PF00412;,3.00E-129,CHOYP_MCA3A.2.2,,,,,,,MICA3_HUMAN,Homo sapiens (Human),actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114] comp134442_c1_seq1,292,43.1507,0.66709611,14,0,,2.00E-15,Q7RTP6,Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),GO:0071949; GO:0003779; GO:0030042; GO:0005737; GO:0005856; GO:0006887; GO:0016709; GO:0008270,"FAD binding; actin binding; actin filament depolymerization; cytoplasm; cytoskeleton; exocytosis; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; zinc ion binding",PF00307;PF12130;PF01494;PF00412;,,,,,,,,,MICA3_HUMAN,Homo sapiens (Human),actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114] comp134443_c0_seq1,628,37.4204,0.27375668,0,0,,,,,,,,,7.00E-35,CHOYP_XPO6.1.1,,,,,,,,, comp134443_c0_seq2,1463,40.6699,0.31435496,39,139,,1.00E-155,Q96QU8,Exportin-6 (Exp6) (Ran-binding protein 20),Exportin-6 (Exp6) (Ran-binding protein 20),GO:0005737; GO:0005730; GO:0005886; GO:0006611; GO:0008565,cytoplasm; nucleolus; plasma membrane; protein export from nucleus; protein transporter activity,PF03810;PF08389;,2.00E-84,CHOYP_XPO6.1.1,,,,,,,XPO6_HUMAN,Homo sapiens (Human),protein export from nucleus [GO:0006611] comp134447_c0_seq1,772,38.0829,1.00180682,11,2,,,,,,,,,3.00E-22,CHOYP_LOC100486607.1.1,,,,,,,,, comp134447_c0_seq2,1775,39.3803,0.93061976,67,76,,9.00E-42,Q5ZKJ5,Transmembrane protein 180,Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A),GO:0016021,integral to membrane,,7.00E-15,CHOYP_BRAFLDRAFT_65831.1.1,,,,,,,TM180_CHICK,Gallus gallus (Chicken), comp134451_c0_seq1,1071,49.0196,0.57738492,0,0,,3.00E-09,Q9MZD2,Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin) (C254) (Fragment),Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin) (C254) (Fragment),GO:0005938; GO:0005856,cell cortex; cytoskeleton,PF00630;,,,,,,,,,FLNB_RABIT,Oryctolagus cuniculus (Rabbit),actin cytoskeleton organization [GO:0030036]; cell differentiation [GO:0030154] comp134451_c0_seq2,1166,49.4854,0.61697111,0,0,,3.00E-29,Q14315,Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),GO:0030018; GO:0034329; GO:0043034; GO:0005856; GO:0005829; GO:0048747; GO:0042383; GO:0016528,Z disc; cell junction assembly; costamere; cytoskeleton; cytosol; muscle fiber development; sarcolemma; sarcoplasm,PF00307;PF00630;,,,,,,,,,FLNC_HUMAN,Homo sapiens (Human),cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747] comp134451_c0_seq3,1182,48.9848,0.63518719,0,0,,3.00E-27,P21333,Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin),Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin),GO:0034988; GO:0031523; GO:0048365; GO:0017160; GO:0051764; GO:0015629; GO:0031532; GO:0051015; GO:0007195; GO:0005938; GO:0034329; GO:0042384; GO:0051220; GO:0005829; GO:0045022; GO:0001837; GO:0045184; GO:0070062; GO:0001948; GO:0042177; GO:0043433; GO:0005634; GO:0005886; GO:0030168; GO:0002576; GO:0043123; GO:0042993; GO:0042803; GO:0034394; GO:0050821; GO:0043113; GO:0004871; GO:0090307; GO:0005802,Fc-gamma receptor I complex binding; Myb complex; Rac GTPase binding; Ral GTPase binding; actin crosslink formation; actin cytoskeleton; actin cytoskeleton reorganization; actin filament binding; adenylate cyclase-inhibiting dopamine receptor signaling pathway; cell cortex; cell junction assembly; cilium assembly; cytoplasmic sequestering of protein; cytosol; early endosome to late endosome transport; epithelial to mesenchymal transition; establishment of protein localization; extracellular vesicular exosome; glycoprotein binding; negative regulation of protein catabolic process; negative regulation of sequence-specific DNA binding transcription factor activity; nucleus; plasma membrane; platelet activation; platelet degranulation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor import into nucleus; protein homodimerization activity; protein localization to cell surface; protein stabilization; receptor clustering; signal transducer activity; spindle assembly involved in mitosis; trans-Golgi network,PF00307;PF00630;,,,,,,,,,FLNA_HUMAN,Homo sapiens (Human),"actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cilium assembly [GO:0042384]; cytoplasmic sequestering of protein [GO:0051220]; establishment of protein localization [GO:0045184]; mitotic spindle assembly [GO:0090307]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase I promoter [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription factor import into nucleus [GO:0042993]; protein localization to cell surface [GO:0034394]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]" comp134452_c0_seq1,1210,42.314,0.6840768,0,6,,2.00E-15,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp134452_c0_seq2,695,48.3453,0.39625745,0,0,,,,,,,,,1.00E-139,CHOYP_SMP_051990.4.7,,,,,,,,, comp134452_c0_seq5,1625,50.0308,0.35425708,0,0,,7.00E-34,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,0,CHOYP_SMP_051990.4.7,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp134452_c1_seq1,620,45,0.57654369,18,64,,,,,,,,,2.00E-66,CHOYP_SMP_149990.1.1.1,,,,,,,,, comp134454_c0_seq1,1631,41.9375,0.82408049,0,208,,1.00E-94,Q761V0,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0016021; GO:0005328,integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,SC6A5_MOUSE,Mus musculus (Mouse),"glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]" comp134454_c0_seq2,863,45.7706,0.66918043,0,0,,3.00E-38,Q96N87,Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3),Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3),GO:0006865; GO:0005887; GO:0005328; GO:0005886; GO:0055085,amino acid transport; integral to plasma membrane; neurotransmitter:sodium symporter activity; plasma membrane; transmembrane transport,PF00209;,,,,,,,,,S6A18_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865] comp134455_c0_seq2,586,43.0034,0.4438017,10,156,,3.00E-58,Q9CXS4,Centromere protein V (CENP-V) (Proline-rich protein 6),Centromere protein V (CENP-V) (Proline-rich protein 6),GO:0001667; GO:0016846; GO:0051301; GO:0031508; GO:0000777; GO:0005737; GO:0000776; GO:0007067; GO:0005634; GO:0032467; GO:0033044; GO:0051233,ameboidal cell migration; carbon-sulfur lyase activity; cell division; centromeric heterochromatin assembly; condensed chromosome kinetochore; cytoplasm; kinetochore; mitosis; nucleus; positive regulation of cytokinesis; regulation of chromosome organization; spindle midzone,PF04828;,6.00E-29,CHOYP_NR1H4.2.2,,,,,,,CENPV_MOUSE,Mus musculus (Mouse),ameboidal-type cell migration [GO:0001667]; cell division [GO:0051301]; centromere complex assembly [GO:0034508]; metabolic process [GO:0008152]; mitotic nuclear division [GO:0007067]; pericentric heterochromatin assembly [GO:0031508]; positive regulation of cytokinesis [GO:0032467]; regulation of chromosome organization [GO:0033044] comp134458_c0_seq2,1519,37.2614,0.99091123,75,23,,3.00E-22,Q69L99,Laccase-14 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase 14) (Diphenol oxidase 14) (Urishiol oxidase 14),Laccase-14 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase 14) (Diphenol oxidase 14) (Urishiol oxidase 14),GO:0048046; GO:0005507; GO:0052716; GO:0046274,apoplast; copper ion binding; hydroquinone:oxygen oxidoreductase activity; lignin catabolic process,PF00394;PF07731;PF07732;,,,6.00E-13,ruditapes_c16938,,,,,LAC14_ORYSJ,Oryza sativa subsp. japonica (Rice),lignin catabolic process [GO:0046274] comp134463_c0_seq1,2464,36.5666,0.49632546,0,0,,0,O55173,3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (Protein kinase B kinase) (PkB kinase),3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (Protein kinase B kinase) (PkB kinase),GO:0004676; GO:0005524; GO:0032148; GO:0032869; GO:0005829; GO:0097191; GO:0005925; GO:0048041; GO:0005158; GO:0035556; GO:0010667; GO:0006469; GO:0034122; GO:0030512; GO:0005634; GO:0018107; GO:0005886; GO:0090004; GO:0019901; GO:0043122; GO:0010594; GO:0043304; GO:0006355; GO:0006351; GO:0003323,"3-phosphoinositide-dependent protein kinase activity; ATP binding; activation of protein kinase B activity; cellular response to insulin stimulus; cytosol; extrinsic apoptotic signaling pathway; focal adhesion; focal adhesion assembly; insulin receptor binding; intracellular signal transduction; negative regulation of cardiac muscle cell apoptotic process; negative regulation of protein kinase activity; negative regulation of toll-like receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; peptidyl-threonine phosphorylation; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; protein kinase binding; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of endothelial cell migration; regulation of mast cell degranulation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; type B pancreatic cell development",PF00069;,,,,,,,,,PDPK1_RAT,Rattus norvegicus (Rat),"activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of endothelial cell migration [GO:0010594]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell development [GO:0003323]" comp134463_c0_seq4,2511,35.8821,0.50612516,0,0,,3.00E-24,O42844,Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17),Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17),GO:0005524; GO:0051519; GO:0005509; GO:0004683; GO:0030428; GO:0034599; GO:0005737; GO:0033314; GO:0031098,ATP binding; activation of bipolar cell growth; calcium ion binding; calmodulin-dependent protein kinase activity; cell septum; cellular response to oxidative stress; cytoplasm; mitotic DNA replication checkpoint; stress-activated protein kinase signaling cascade,PF00069;,0,CHOYP_LOC100533218.1.1,,,,,,,KCC2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular response to oxidative stress [GO:0034599]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; protein autophosphorylation [GO:0046777]; stress-activated protein kinase signaling cascade [GO:0031098] comp134464_c1_seq1,1492,39.3432,0.72803934,302,93,,4.00E-132,Q9WTK8,Meiotic recombination protein SPO11,Meiotic recombination protein SPO11 (EC 5.99.1.3),GO:0005524; GO:0003677; GO:0000781; GO:0016787; GO:0007141; GO:0005654; GO:0001541; GO:0034502; GO:0007131; GO:0007286; GO:0007129,"ATP binding; DNA binding; chromosome, telomeric region; hydrolase activity; male meiosis I; nucleoplasm; ovarian follicle development; protein localization to chromosome; reciprocal meiotic recombination; spermatid development; synapsis",PF03533;PF04406;,9.00E-13,CHOYP_SPO11.1.1,,,,,,,SPO11_MOUSE,Mus musculus (Mouse),"DNA catabolic process, endonucleolytic [GO:0000737]; male meiosis I [GO:0007141]; meiotic telomere clustering [GO:0045141]; oogenesis [GO:0048477]; ovarian follicle development [GO:0001541]; protein localization to chromosome [GO:0034502]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]" comp134466_c0_seq1,891,42.312,0.68595177,159,357,,5.00E-35,Q6PEE2,CBP80/20-dependent translation initiation factor,CBP80/20-dependent translation initiation factor,GO:0003723; GO:0000184; GO:0048471; GO:0006446,"RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; perinuclear region of cytoplasm; regulation of translational initiation",PF02854;,,,,,,,,,CTIF_MOUSE,Mus musculus (Mouse),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translational initiation [GO:0006446]" comp134468_c0_seq2,1665,40.6607,0.51157219,20,5,,6.00E-81,Q15853,Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2),Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2),GO:0000978; GO:0003705; GO:0003690; GO:0007595; GO:0019086; GO:0055088; GO:0005634; GO:0045944; GO:0000432; GO:0043565; GO:0003700; GO:0006351,"RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; double-stranded DNA binding; lactation; late viral mRNA transcription; lipid homeostasis; nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter by glucose; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00010;,5.00E-73,CHOYP_LOC100552087.1.1,,,,,,,USF2_HUMAN,Homo sapiens (Human),lactation [GO:0007595]; late viral transcription [GO:0019086]; lipid homeostasis [GO:0055088]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; regulation of transcription from RNA polymerase II promoter by glucose [GO:0000430]; transcription from RNA polymerase II promoter [GO:0006366] comp134471_c0_seq1,1153,48.3955,0.9657284,276,19,,3.00E-52,A2A3V2,Solute carrier family 25 member 43,Solute carrier family 25 member 43,GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,,,,,,,,,S2543_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transmembrane transport [GO:0055085] comp134472_c3_seq1,1266,42.2591,0.45584751,45,144,,7.00E-30,Q08CY1,Kelch-like protein 22,Kelch-like protein 22,GO:0031463; GO:0051301; GO:0005813; GO:0005737; GO:0000070; GO:0072686; GO:0007094; GO:0005827; GO:0006513,Cul3-RING ubiquitin ligase complex; cell division; centrosome; cytoplasm; mitotic sister chromatid segregation; mitotic spindle; mitotic spindle assembly checkpoint; polar microtubule; protein monoubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH22_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein monoubiquitination [GO:0006513] comp134475_c0_seq1,1125,42.9333,0.36751902,69,537,,9.00E-67,Q6KAQ7,ZZ-type zinc finger-containing protein 3,ZZ-type zinc finger-containing protein 3,GO:0005671; GO:0003677; GO:0003682; GO:0006355; GO:0006351; GO:0008270,"Ada2/Gcn5/Ada3 transcription activator complex; DNA binding; chromatin binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00249;PF00569;,,,,,,,,,ZZZ3_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134477_c0_seq1,1801,44.3087,0.71489496,28,32,,0,Q7SYN5,Retinoic acid receptor RXR-beta-A (Nuclear receptor subfamily 2 group B member 2-A) (Retinoid X receptor beta-A),Retinoic acid receptor RXR-beta-A (Nuclear receptor subfamily 2 group B member 2-A) (Retinoid X receptor beta-A),GO:0004886; GO:0045892; GO:0005634; GO:0043565; GO:0003707; GO:0008270,"9-cis retinoic acid receptor activity; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding",PF00104;PF11825;PF00105;,0,CHOYP_RXR.2.2,,,,,,,RXRBA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134477_c0_seq2,1762,44.4381,0.7385939,12,13,,0,Q8T5C6,Retinoic acid receptor RXR (RXR-like protein) (Retinoid X receptor) (BgRXR),Retinoic acid receptor RXR (RXR-like protein) (Retinoid X receptor) (BgRXR),GO:0005634; GO:0016918; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; retinal binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,0,CHOYP_RXR.1.2,,,,,,,RXR_BIOGL,Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail),"transcription, DNA-templated [GO:0006351]" comp134481_c0_seq1,1211,47.8117,0.85566649,2372,338,,8.00E-07,Q8MI69,WAP four-disulfide core domain protein 2 (Epididymal secretory protein E4),WAP four-disulfide core domain protein 2 (Epididymal secretory protein E4),GO:0019828; GO:0004869; GO:0005576; GO:0004867,aspartic-type endopeptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity; extracellular region; serine-type endopeptidase inhibitor activity,PF00095;,,,,,,,,,WFDC2_PIG,Sus scrofa (Pig), comp134482_c0_seq1,1677,42.7549,0.44397768,136,267,,2.00E-18,Q6GLQ4,Serine/threonine-protein phosphatase 1 regulatory subunit 10,Serine/threonine-protein phosphatase 1 regulatory subunit 10,GO:0003677; GO:0046872; GO:0005634; GO:0004864; GO:0006351,"DNA binding; metal ion binding; nucleus; protein phosphatase inhibitor activity; transcription, DNA-dependent",PF08711;,,,,,,,,,PP1RA_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp134483_c0_seq1,983,35.9105,0.83248817,41,681,,1.00E-98,Q95NR9,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,3.00E-112,CHOYP_LOC100372664.2.2,2.00E-130,ruditapes_c2436,,,,,CALM_METSE,Metridium senile (Brown sea anemone) (Frilled sea anemone), comp134483_c0_seq2,975,36.4103,0.91581019,24,613,,1.00E-97,O16305,Calmodulin (CaM),Calmodulin (CaM),GO:0043277; GO:0005509; GO:0016477; GO:0071944; GO:0005813; GO:0009790; GO:0051296; GO:0072686; GO:0031965; GO:0042981; GO:0051726; GO:0032880,apoptotic cell clearance; calcium ion binding; cell migration; cell periphery; centrosome; embryo development; establishment of meiotic spindle orientation; mitotic spindle; nuclear membrane; regulation of apoptotic process; regulation of cell cycle; regulation of protein localization,PF13499;,1.00E-97,CHOYP_CALM.42.50,2.00E-23,ruditapes_c28633,,,,,CALM_CAEEL,Caenorhabditis elegans,apoptotic cell clearance [GO:0043277]; cell migration [GO:0016477]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of meiotic spindle orientation [GO:0051296]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of protein localization [GO:0032880] comp134485_c0_seq1,1091,33.3639,0.33111004,595,2653,,3.00E-08,Q9CQA6,"Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (28S ribosomal protein S37, mitochondrial) (MRP-S37)","Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (28S ribosomal protein S37, mitochondrial) (MRP-S37)",GO:0005739; GO:0005730,mitochondrion; nucleolus,PF06747;,,,,,,,,,CHCH1_MOUSE,Mus musculus (Mouse), comp134488_c0_seq1,938,35.9275,0.47301435,876,1751,,4.00E-38,Q16595,"Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)]","Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)]",GO:0051537; GO:0007628; GO:0009060; GO:0006879; GO:0070301; GO:0005829; GO:0009792; GO:0008199; GO:0008198; GO:0004322; GO:0006783; GO:0006811; GO:0034986; GO:0018283; GO:0005759; GO:0007005; GO:0043066; GO:0040015; GO:0046621; GO:0090201; GO:0006119; GO:0045773; GO:0030307; GO:0008284; GO:0051349; GO:0048554; GO:0051353; GO:0051347; GO:0019230; GO:0016540; GO:0010722; GO:0042493; GO:0010039; GO:0014070; GO:0044281,"2 iron, 2 sulfur cluster binding; adult walking behavior; aerobic respiration; cellular iron ion homeostasis; cellular response to hydrogen peroxide; cytosol; embryo development ending in birth or egg hatching; ferric iron binding; ferrous iron binding; ferroxidase activity; heme biosynthetic process; ion transport; iron chaperone activity; iron incorporation into metallo-sulfur cluster; mitochondrial matrix; mitochondrion organization; negative regulation of apoptotic process; negative regulation of multicellular organism growth; negative regulation of organ growth; negative regulation of release of cytochrome c from mitochondria; oxidative phosphorylation; positive regulation of axon extension; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of lyase activity; positive regulation of metalloenzyme activity; positive regulation of oxidoreductase activity; positive regulation of transferase activity; proprioception; protein autoprocessing; regulation of ferrochelatase activity; response to drug; response to iron ion; response to organic cyclic compound; small molecule metabolic process",PF01491;,,,,,,,,,FRDA_HUMAN,Homo sapiens (Human),adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281] comp134489_c1_seq1,420,38.0952,0.85636536,9,92,,8.00E-09,Q4IPI4,Actin-related protein 4 (Actin-like protein ARP4) (Actin-like protein 4),Actin-related protein 4 (Actin-like protein ARP4) (Actin-like protein 4),GO:0006281; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA repair; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00022;,,,1.00E-15,ruditapes2_lrc4806,,,,,ARP4_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),"chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134489_c1_seq2,949,45.627,0.83709528,1,257,female>male,2.00E-134,Q964D9,"Actin, cytoplasmic","Actin, cytoplasmic",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,6.00E-57,CHOYP_ACT5.1.3,2.00E-66,ruditapes_lrc32388,,,,,ACTC_HELTI,Planorbella trivolvis (Marsh rams-horn) (Helisoma trivolvis), comp134497_c1_seq1,2557,42.7845,0.62388325,0,0,,3.00E-23,Q92547,DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1),DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1),GO:0003677; GO:0006281; GO:0016605; GO:0005694; GO:0000794; GO:0005737; GO:0001673; GO:0005815; GO:0008022; GO:0010212; GO:0000922,DNA binding; DNA repair; PML body; chromosome; condensed nuclear chromosome; cytoplasm; male germ cell nucleus; microtubule organizing center; protein C-terminus binding; response to ionizing radiation; spindle pole,PF00533;PF12738;,,,,,,,,,TOPB1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to ionizing radiation [GO:0010212] comp134497_c1_seq2,2640,42.9924,0.63219335,0,0,,0,Q9H8V3,Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene),Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene),GO:0005096; GO:0005089; GO:0032863; GO:0032147; GO:0097190; GO:0000902; GO:0071277; GO:0070301; GO:0071479; GO:0097149; GO:0032154; GO:0000910; GO:0005829; GO:0030496; GO:0048011; GO:0005634; GO:0005543; GO:0043089; GO:0043123; GO:0043065; GO:0032467; GO:0045666; GO:0042307; GO:0042803; GO:0051260; GO:0015031; GO:0051988; GO:0004871; GO:0007264; GO:0005923; GO:0070830,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; activation of Rac GTPase activity; activation of protein kinase activity; apoptotic signaling pathway; cell morphogenesis; cellular response to calcium ion; cellular response to hydrogen peroxide; cellular response to ionizing radiation; centralspindlin complex; cleavage furrow; cytokinesis; cytosol; midbody; neurotrophin TRK receptor signaling pathway; nucleus; phospholipid binding; positive regulation of Cdc42 GTPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of cytokinesis; positive regulation of neuron differentiation; positive regulation of protein import into nucleus; protein homodimerization activity; protein homooligomerization; protein transport; regulation of attachment of spindle microtubules to kinetochore; signal transducer activity; small GTPase mediated signal transduction; tight junction; tight junction assembly,PF00533;PF12738;PF00621;,9.00E-98,CHOYP_ECT2.1.1,,,,,,,ECT2_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of protein kinase activity [GO:0045859]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp134497_c1_seq5,2584,42.8019,0.61539373,0,0,,4.00E-23,Q92547,DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1),DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1),GO:0003677; GO:0006281; GO:0016605; GO:0005694; GO:0000794; GO:0005737; GO:0001673; GO:0005815; GO:0008022; GO:0010212; GO:0000922,DNA binding; DNA repair; PML body; chromosome; condensed nuclear chromosome; cytoplasm; male germ cell nucleus; microtubule organizing center; protein C-terminus binding; response to ionizing radiation; spindle pole,PF00533;PF12738;,,,,,,,,,TOPB1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to ionizing radiation [GO:0010212] comp134497_c1_seq6,2667,43.0071,0.62392436,0,0,,0,Q9H8V3,Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene),Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene),GO:0005096; GO:0005089; GO:0032863; GO:0032147; GO:0097190; GO:0000902; GO:0071277; GO:0070301; GO:0071479; GO:0097149; GO:0032154; GO:0000910; GO:0005829; GO:0030496; GO:0048011; GO:0005634; GO:0005543; GO:0043089; GO:0043123; GO:0043065; GO:0032467; GO:0045666; GO:0042307; GO:0042803; GO:0051260; GO:0015031; GO:0051988; GO:0004871; GO:0007264; GO:0005923; GO:0070830,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; activation of Rac GTPase activity; activation of protein kinase activity; apoptotic signaling pathway; cell morphogenesis; cellular response to calcium ion; cellular response to hydrogen peroxide; cellular response to ionizing radiation; centralspindlin complex; cleavage furrow; cytokinesis; cytosol; midbody; neurotrophin TRK receptor signaling pathway; nucleus; phospholipid binding; positive regulation of Cdc42 GTPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of cytokinesis; positive regulation of neuron differentiation; positive regulation of protein import into nucleus; protein homodimerization activity; protein homooligomerization; protein transport; regulation of attachment of spindle microtubules to kinetochore; signal transducer activity; small GTPase mediated signal transduction; tight junction; tight junction assembly,PF00533;PF12738;PF00621;,1.00E-96,CHOYP_ECT2.1.1,,,,,,,ECT2_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of protein kinase activity [GO:0045859]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp134499_c0_seq1,1393,36.2527,0.94287021,0,51,,7.00E-22,Q8RV79,Cytosolic sulfotransferase 11 (AtSOT11) (EC 2.8.2.-),Cytosolic sulfotransferase 11 (AtSOT11) (EC 2.8.2.-),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,,,,,,,,,SOT11_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp134499_c0_seq2,1324,36.858,0.89359529,0,7,,5.00E-40,Q9BR01,Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST),Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST),GO:0050427; GO:0005829; GO:0008202; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; steroid metabolic process; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST4A1_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; steroid metabolic process [GO:0008202] comp134505_c0_seq1,1004,39.6414,0.50043292,0,12,,5.00E-70,B4KKD5,"Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)","Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)",GO:0005525; GO:0003924; GO:0070125; GO:0005739; GO:0003746,GTP binding; GTPase activity; mitochondrial translational elongation; mitochondrion; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,,,,,,,,,EFGM_DROMO,Drosophila mojavensis (Fruit fly),mitochondrial translational elongation [GO:0070125] comp134505_c0_seq2,2300,41.7826,0.53300671,0,0,,2.00E-64,P29541,Elongation factor G (EF-G) (Fragment),Elongation factor G (EF-G) (Fragment),GO:0005525; GO:0005737; GO:0003746,GTP binding; cytoplasm; translation elongation factor activity,PF00679;PF14492;PF03764;,0,CHOYP_EFGM.1.1,,,,,,,EFG_STRRA,Streptomyces ramocissimus, comp134505_c0_seq3,2719,41.4491,0.54544506,19,15,,0,Q16S14,"Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)","Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)",GO:0005525; GO:0003924; GO:0070125; GO:0005739; GO:0003746,GTP binding; GTPase activity; mitochondrial translational elongation; mitochondrion; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,0,CHOYP_EFGM.1.1,,,,,,,EFGM_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),mitochondrial translational elongation [GO:0070125] comp134509_c0_seq1,1930,43.3161,0.55694976,0,0,,6.00E-07,Q03573,Uncharacterized protein C40H1.3,Uncharacterized protein C40H1.3,,,,2.00E-123,CHOYP_LOC100369449.1.1,,,,,,,YLF3_CAEEL,Caenorhabditis elegans, comp134509_c0_seq2,2358,43.7659,0.56950595,43,19,,1.00E-101,O60308,Centrosomal protein of 104 kDa (Cep104),Centrosomal protein of 104 kDa (Cep104),GO:0005814,centriole,,,,,,,,,,CE104_HUMAN,Homo sapiens (Human), comp134519_c0_seq6,759,37.4177,0.38060964,0,0,,2.00E-07,Q8TA86,Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1),Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1),GO:0008380; GO:0003676; GO:0005634; GO:0005785; GO:0008270,RNA splicing; nucleic acid binding; nucleus; signal recognition particle receptor complex; zinc ion binding,,,,,,,,,,RP9_HUMAN,Homo sapiens (Human),cognition [GO:0050890]; RNA splicing [GO:0008380] comp134524_c0_seq2,491,40.5295,0.56848975,46,258,,2.00E-22,Q1RMP0,DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1),DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1),GO:0003899; GO:0003676; GO:0005730; GO:0006351; GO:0008270,"DNA-directed RNA polymerase activity; nucleic acid binding; nucleolus; transcription, DNA-dependent; zinc ion binding",PF01096;,,,,,,,,,RPA12_BOVIN,Bos taurus (Bovine),termination of RNA polymerase I transcription [GO:0006363] comp134530_c1_seq1,693,34.3434,0.41171758,0,0,,4.00E-25,P52655,Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)],Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)],GO:0003677; GO:0006355; GO:0003713; GO:0006368; GO:0005672; GO:0006367; GO:0016032,"DNA binding; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription elongation from RNA polymerase II promoter; transcription factor TFIIA complex; transcription initiation from RNA polymerase II promoter; viral process",PF03153;,,,,,,,,,TF2AA_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp134530_c1_seq2,722,35.0416,0.44814136,1,25,,,,,,,,,7.00E-42,CHOYP_TF2AA.1.1,,,,,,,,, comp134534_c3_seq1,269,36.0595,0.34527331,15,0,,3.00E-07,P97386,DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),GO:0005524; GO:0003677; GO:0003910; GO:0006266; GO:0051103; GO:0006310; GO:0006260; GO:0007049; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0043504; GO:0045910; GO:0006289; GO:0005634; GO:0000795; GO:0008270,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation; DNA ligation involved in DNA repair; DNA recombination; DNA replication; cell cycle; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; mitochondrial DNA repair; negative regulation of DNA recombination; nucleotide-excision repair; nucleus; synaptonemal complex; zinc ion binding,PF04679;PF01068;PF04675;PF16759;PF00645;,,,,,,,,,DNLI3_MOUSE,Mus musculus (Mouse),"base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of DNA recombination [GO:0045910]; negative regulation of mitochondrial DNA replication [GO:0090298]" comp134541_c0_seq1,2123,41.9218,0.38789609,87,199,,5.00E-101,O43149,Zinc finger ZZ-type and EF-hand domain-containing protein 1,Zinc finger ZZ-type and EF-hand domain-containing protein 1,GO:0005509; GO:0008270,calcium ion binding; zinc ion binding,PF03256;PF00569;,1.00E-63,CHOYP_BRAFLDRAFT_88583.1.1,,,,,,,ZZEF1_HUMAN,Homo sapiens (Human), comp134543_c0_seq1,1010,39.703,0.41256927,127,625,,2.00E-21,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,,,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp134547_c1_seq1,1319,41.3192,0.58748989,0,0,,4.00E-46,Q8IMA8,"Protein pangolin, isoform J (dTCF)","Protein pangolin, isoform J (dTCF)",GO:0003705; GO:0008013; GO:0060070; GO:0009880; GO:0007507; GO:0007476; GO:0007500; GO:0005875; GO:0030178; GO:0045892; GO:0005634; GO:0045944; GO:0045610; GO:0072091; GO:0007435; GO:0007367; GO:0043565; GO:0035277; GO:0005667; GO:0044212,"RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; beta-catenin binding; canonical Wnt receptor signaling pathway; embryonic pattern specification; heart development; imaginal disc-derived wing morphogenesis; mesodermal cell fate determination; microtubule associated complex; negative regulation of Wnt receptor signaling pathway; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of hemocyte differentiation; regulation of stem cell proliferation; salivary gland morphogenesis; segment polarity determination; sequence-specific DNA binding; spiracle morphogenesis, open tracheal system; transcription factor complex; transcription regulatory region DNA binding",PF00505;,5.00E-41,CHOYP_PANG1.2.2,,,,,,,PANG2_DROME,Drosophila melanogaster (Fruit fly),"canonical Wnt signaling pathway [GO:0060070]; embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; mesodermal cell fate determination [GO:0007500]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of hemocyte differentiation [GO:0045610]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; salivary gland morphogenesis [GO:0007435]; segment polarity determination [GO:0007367]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]; Wnt signaling pathway [GO:0016055]" comp134547_c1_seq2,2350,42.7234,0.60756611,0,0,,8.00E-47,Q9YHE8,Transcription factor 7-like 1-A (HMG box transcription factor 3-A) (TCF-3) (TCF-3-A) (zTcf-3) (Protein headless),Transcription factor 7-like 1-A (HMG box transcription factor 3-A) (TCF-3) (TCF-3-A) (zTcf-3) (Protein headless),GO:0008013; GO:0060070; GO:0010456; GO:0003682; GO:0048596; GO:0030900; GO:0048699; GO:0060323; GO:0030901; GO:0030178; GO:0005634; GO:0008284; GO:0006357; GO:0021903; GO:0043565; GO:0003700; GO:0005667; GO:0044212; GO:0006351,"beta-catenin binding; canonical Wnt receptor signaling pathway; cell proliferation in dorsal spinal cord; chromatin binding; embryonic camera-type eye morphogenesis; forebrain development; generation of neurons; head morphogenesis; midbrain development; negative regulation of Wnt receptor signaling pathway; nucleus; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; rostrocaudal neural tube patterning; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent",PF08347;PF00505;,,,,,,,,,T7L1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"canonical Wnt signaling pathway [GO:0060070]; cell proliferation in dorsal spinal cord [GO:0010456]; embryonic camera-type eye morphogenesis [GO:0048596]; endothelial cell fate specification [GO:0060847]; forebrain development [GO:0030900]; generation of neurons [GO:0048699]; head morphogenesis [GO:0060323]; heart development [GO:0007507]; midbrain development [GO:0030901]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; rostrocaudal neural tube patterning [GO:0021903]; transcription, DNA-templated [GO:0006351]" comp134547_c1_seq3,1264,41.4557,0.5718143,0,0,,3.00E-09,P40645,Transcription factor SOX-6 (SOX-LZ),Transcription factor SOX-6 (SOX-LZ),GO:0035051; GO:0051216; GO:0000902; GO:0048821; GO:0016458; GO:0001701; GO:0042692; GO:0000122; GO:0005634; GO:0021778; GO:0032332; GO:0045944; GO:0009791; GO:0043565; GO:0003700; GO:0005667; GO:0044212; GO:0006351,"cardiocyte differentiation; cartilage development; cell morphogenesis; erythrocyte development; gene silencing; in utero embryonic development; muscle cell differentiation; negative regulation of transcription from RNA polymerase II promoter; nucleus; oligodendrocyte cell fate specification; positive regulation of chondrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00505;,4.00E-41,CHOYP_PANG1.2.2,,,,,,,SOX6_MOUSE,Mus musculus (Mouse),"astrocyte differentiation [GO:0048708]; cardiac muscle cell differentiation [GO:0055007]; cartilage development [GO:0051216]; cell fate commitment [GO:0045165]; cell morphogenesis [GO:0000902]; cellular response to transforming growth factor beta stimulus [GO:0071560]; erythrocyte development [GO:0048821]; erythrocyte differentiation [GO:0030218]; gene silencing [GO:0016458]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; muscle cell differentiation [GO:0042692]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oligodendrocyte cell fate specification [GO:0021778]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134547_c1_seq4,2405,42.6195,0.61514343,0,0,,4.00E-59,P91943,"Protein pangolin, isoforms A/H/I/S (dTCF)","Protein pangolin, isoforms A/H/I/S (dTCF)",GO:0003705; GO:0008013; GO:0060070; GO:0009880; GO:0007507; GO:0007476; GO:0007500; GO:0005875; GO:0030178; GO:0045892; GO:0005634; GO:0045944; GO:0045610; GO:0072091; GO:0007435; GO:0007367; GO:0043565; GO:0035277; GO:0005667; GO:0044212,"RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; beta-catenin binding; canonical Wnt receptor signaling pathway; embryonic pattern specification; heart development; imaginal disc-derived wing morphogenesis; mesodermal cell fate determination; microtubule associated complex; negative regulation of Wnt receptor signaling pathway; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of hemocyte differentiation; regulation of stem cell proliferation; salivary gland morphogenesis; segment polarity determination; sequence-specific DNA binding; spiracle morphogenesis, open tracheal system; transcription factor complex; transcription regulatory region DNA binding",PF08347;PF00505;,,,,,,,,,PANG1_DROME,Drosophila melanogaster (Fruit fly),"embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; mesodermal cell fate determination [GO:0007500]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of hemocyte differentiation [GO:0045610]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; salivary gland morphogenesis [GO:0007435]; segment polarity determination [GO:0007367]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]; Wnt signaling pathway [GO:0016055]" comp134552_c0_seq1,386,39.8964,0.41170489,18,18,,,,,,,,,,,2.00E-24,ruditapes_c6973,,,,,,, comp134552_c1_seq2,347,41.4986,0.33591013,3,10,,,,,,,,,2.00E-56,CHOYP_CPNE8.1.2,,,,,,,,, comp134552_c1_seq3,1360,50.2941,0.24577786,0,0,,4.00E-100,Q9DC53,Copine-8 (Copine VIII),Copine-8 (Copine VIII),,,PF00168;PF07002;,1.00E-68,CHOYP_CPNE8.2.2,,,,,,,CPNE8_MOUSE,Mus musculus (Mouse), comp134552_c1_seq5,1416,48.3051,0.30477066,0,0,,1.00E-21,Q9SS90,E3 ubiquitin-protein ligase RGLG1 (EC 6.3.2.-) (RING domain ligase 1),E3 ubiquitin-protein ligase RGLG1 (EC 6.3.2.-) (RING domain ligase 1),GO:0009850; GO:0009690; GO:0080148; GO:0005886; GO:0004842; GO:0008270,auxin metabolic process; cytokinin metabolic process; negative regulation of response to water deprivation; plasma membrane; ubiquitin-protein ligase activity; zinc ion binding,PF07002;,2.00E-70,CHOYP_LOC586076.1.1,,,,,,,RGLG1_ARATH,Arabidopsis thaliana (Mouse-ear cress),negative regulation of response to water deprivation [GO:0080148] comp134552_c1_seq7,1721,47.1238,0.356587,0,0,,1.00E-113,Q96FN4,Copine-2 (Copine II),Copine-2 (Copine II),,,PF00168;PF07002;,,,,,,,,,CPNE2_HUMAN,Homo sapiens (Human),cellular response to calcium ion [GO:0071277] comp134552_c1_seq8,1665,48.7087,0.30434794,0,0,,3.00E-146,Q9DC53,Copine-8 (Copine VIII),Copine-8 (Copine VIII),,,PF00168;PF07002;,2.00E-92,CHOYP_CPNE8.2.2,,,,,,,CPNE8_MOUSE,Mus musculus (Mouse), comp134555_c1_seq1,274,41.6058,0.84877674,9,17,,5.00E-17,Q29257,Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog) (Fragment),Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog) (Fragment),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN31_PIG,Sus scrofa (Pig),cell surface receptor signaling pathway [GO:0007166] comp134555_c2_seq1,1399,34.5247,0.27057432,0,0,,3.00E-25,Q7ZUB3,Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog),Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN31_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166] comp134555_c2_seq6,656,38.4146,0.29330425,0,0,,1.00E-26,Q7ZUB3,Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog),Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog),GO:0016021,integral to membrane,PF00335;,3.00E-14,CHOYP_TSN13.2.2,,,,,,,TSN31_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166] comp134555_c2_seq7,1490,34.8322,0.2933264,0,0,,2.00E-24,Q9D8C2,Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13),Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13),GO:0016021,integral to membrane,PF00335;,4.00E-23,CHOYP_LOC100867334.1.1,,,,,,,TSN13_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166]; regulation of calcium ion transmembrane transport [GO:1903169] comp134557_c0_seq2,951,32.1767,0.32534531,35,29,,1.00E-49,Q792Q4,Cysteine-rich PDZ-binding protein (Cysteine-rich interactor of PDZ three) (Cysteine-rich interactor of PDZ3),Cysteine-rich PDZ-binding protein (Cysteine-rich interactor of PDZ three) (Cysteine-rich interactor of PDZ3),GO:0030165; GO:0030054; GO:0005737; GO:0031122; GO:0043198; GO:0043197; GO:0045184; GO:0043025; GO:0014069,PDZ domain binding; cell junction; cytoplasm; cytoplasmic microtubule organization; dendritic shaft; dendritic spine; establishment of protein localization; neuronal cell body; postsynaptic density,PF10235;,6.00E-51,CHOYP_LOC100368616.1.1,,,,,,,CRIPT_RAT,Rattus norvegicus (Rat),cytoplasmic microtubule organization [GO:0031122]; establishment of protein localization [GO:0045184]; protein localization to microtubule [GO:0035372]; regulation of postsynaptic density protein 95 clustering [GO:1902897] comp134565_c0_seq1,1279,45.4261,0.46116183,134,138,,7.00E-71,Q9Z0R4,Intersectin-1 (EH and SH3 domains protein 1),Intersectin-1 (EH and SH3 domains protein 1),GO:0005089; GO:0005509; GO:0030054; GO:0005905; GO:0030139; GO:0006897; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0005543; GO:0005886; GO:0051897; GO:0035023; GO:0007264; GO:0045202,Rho guanyl-nucleotide exchange factor activity; calcium ion binding; cell junction; coated pit; endocytic vesicle; endocytosis; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; phospholipid binding; plasma membrane; positive regulation of protein kinase B signaling cascade; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; synapse,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,2.00E-33,CHOYP_ITSN1.2.4,,,,,,,ITSN1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134565_c1_seq1,641,49.454,0.38501613,4,7,,3.00E-62,Q15811,Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),GO:0005089; GO:0097190; GO:0005509; GO:0030054; GO:0005905; GO:0005829; GO:0030139; GO:0005085; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0048011; GO:0005543; GO:0005886; GO:0043065; GO:0051897; GO:0032947; GO:0035023; GO:0051056; GO:0007264; GO:0045202; GO:0048488,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; calcium ion binding; cell junction; coated pit; cytosol; endocytic vesicle; guanyl-nucleotide exchange factor activity; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; positive regulation of apoptotic process; positive regulation of protein kinase B signaling cascade; protein complex scaffold; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; synapse; synaptic vesicle endocytosis,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,1.00E-57,CHOYP_ITSN1.4.4,,,,,,,ITSN1_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488] comp134565_c1_seq2,791,45.1327,0.35468037,14,12,,2.00E-15,Q99M51,Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1),Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1),GO:0042110; GO:0007015; GO:0016477; GO:0005783; GO:0030032; GO:0060548; GO:0005634; GO:0042102; GO:0030838; GO:0045944; GO:0004860; GO:0006417; GO:0051707; GO:0012506,T cell activation; actin filament organization; cell migration; endoplasmic reticulum; lamellipodium assembly; negative regulation of cell death; nucleus; positive regulation of T cell proliferation; positive regulation of actin filament polymerization; positive regulation of transcription from RNA polymerase II promoter; protein kinase inhibitor activity; regulation of translation; response to other organism; vesicle membrane,PF00017;PF00018;PF14604;,6.00E-50,CHOYP_ITSN2.1.1,,,,,,,NCK1_MOUSE,Mus musculus (Mouse),"actin filament organization [GO:0007015]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; lamellipodium assembly [GO:0030032]; negative regulation of cell death [GO:0060548]; negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cap-dependent translational initiation [GO:1903676]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cell migration [GO:0030334]; response to other organism [GO:0051707]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell activation [GO:0042110]; vesicle-mediated transport [GO:0016192]" comp134566_c0_seq1,683,41.4348,0.24376389,24,276,,3.00E-76,A1A4M4,Putative deoxyribonuclease TATDN3 (EC 3.1.21.-),Putative deoxyribonuclease TATDN3 (EC 3.1.21.-),GO:0016888; GO:0046872; GO:0090305; GO:0005634,"endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus",PF01026;,2.00E-23,CHOYP_TATD3.1.2,4.00E-74,ruditapes_c17189,,,,,TATD3_BOVIN,Bos taurus (Bovine), comp134566_c0_seq2,740,41.3514,0.22543394,0,110,,1.00E-63,Q05AV0,Putative deoxyribonuclease tatdn3-A (EC 3.1.21.-),Putative deoxyribonuclease tatdn3-A (EC 3.1.21.-),GO:0016888; GO:0046872; GO:0090305; GO:0005634,"endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus",PF01026;,4.00E-33,CHOYP_TATD3.2.2,,,,,,,TAT3A_XENLA,Xenopus laevis (African clawed frog), comp134566_c1_seq1,594,35.3535,0.32407499,147,1289,,,,,,,,,,,2.00E-44,ruditapes_c8743,,,,,,, comp134570_c0_seq1,1300,39.2308,0.40136382,135,1425,,3.00E-100,A6H791,tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A),tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A),GO:0005634; GO:0016429; GO:0031515,nucleus; tRNA (adenine-N1-)-methyltransferase activity; tRNA (m1A) methyltransferase complex,PF08704;,2.00E-89,CHOYP_BRAFLDRAFT_114350.1.1,,,,,,,TRM61_BOVIN,Bos taurus (Bovine), comp134572_c0_seq12,1594,46.1731,0.59397348,0,0,,2.00E-19,O70468,"Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)","Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)",GO:0031672; GO:0060048; GO:0007155; GO:0005856; GO:0003007; GO:0046872; GO:0032982; GO:0031034; GO:0002027; GO:0045214; GO:0005200,A band; cardiac muscle contraction; cell adhesion; cytoskeleton; heart morphogenesis; metal ion binding; myosin filament; myosin filament assembly; regulation of heart rate; sarcomere organization; structural constituent of cytoskeleton,PF00041;PF07679;,,,,,,,,,MYPC3_MOUSE,Mus musculus (Mouse),cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle contraction [GO:0006936]; myosin filament assembly [GO:0031034]; regulation of heart contraction [GO:0008016]; regulation of heart rate [GO:0002027]; sarcomere organization [GO:0045214]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] comp134572_c0_seq3,1045,44.689,0.49375069,0,0,,3.00E-32,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,4.00E-53,CHOYP_PHUM_PHUM226120.3.7,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp134572_c0_seq4,1321,46.4799,0.56384547,0,0,,8.00E-10,Q90233,"Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) (CPRO axocard 1) (Fragment)","Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) (CPRO axocard 1) (Fragment)",GO:0007155; GO:0032982,cell adhesion; myosin filament,PF07679;,,,,,,,,,MYPC3_AMBME,Ambystoma mexicanum (Axolotl),cell adhesion [GO:0007155] comp134572_c0_seq5,744,45.0269,0.4101828,0,0,,2.00E-07,Q15746,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0060414; GO:0032060; GO:0071476; GO:0032154; GO:0005829; GO:0030027; GO:0046872; GO:0004687; GO:0005886; GO:0051928; GO:0030335; GO:0090303; GO:0001725; GO:0014820,ATP binding; aorta smooth muscle tissue morphogenesis; bleb assembly; cellular hypotonic response; cleavage furrow; cytosol; lamellipodium; metal ion binding; myosin light chain kinase activity; plasma membrane; positive regulation of calcium ion transport; positive regulation of cell migration; positive regulation of wound healing; stress fiber; tonic smooth muscle contraction,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_HUMAN,Homo sapiens (Human),aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792] comp134572_c0_seq6,1642,46.1023,0.61595051,0,0,,4.00E-38,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,4.00E-55,CHOYP_PHUM_PHUM226120.7.7,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp134572_c0_seq8,1268,44.6372,0.51634592,0,0,,8.00E-29,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,3.00E-55,CHOYP_PHUM_PHUM226120.7.7,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp134573_c1_seq1,1543,37.5891,0.67024184,0,0,,3.00E-49,Q9SZ53,Probable protein phosphatase 2C 60 (AtPP2C60) (EC 3.1.3.16),Probable protein phosphatase 2C 60 (AtPP2C60) (EC 3.1.3.16),GO:0046872; GO:0005886; GO:0006470; GO:0004722,metal ion binding; plasma membrane; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C60_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp134573_c1_seq2,1287,37.4514,0.67994008,0,0,,2.00E-08,Q93YS2,Probable protein phosphatase 2C 51 (AtPP2C51) (EC 3.1.3.16),Probable protein phosphatase 2C 51 (AtPP2C51) (EC 3.1.3.16),GO:0016021; GO:0008152; GO:0046872; GO:0004721,integral to membrane; metabolic process; metal ion binding; phosphoprotein phosphatase activity,PF00481;,,,,,,,,,P2C51_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp134573_c1_seq3,1780,38.0899,0.6063399,35,22,,3.00E-145,P49596,Probable protein phosphatase 2C T23F11.1 (PP2C) (EC 3.1.3.16),Probable protein phosphatase 2C T23F11.1 (PP2C) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,1.00E-137,CHOYP_NEMVEDRAFT_V1G167304.1.1,,,,,,,PP2C2_CAEEL,Caenorhabditis elegans,negative regulation of axon extension [GO:0030517]; positive regulation of synapse assembly [GO:0051965] comp134574_c2_seq1,343,41.3994,0.69622126,6,10,,5.00E-11,Q9UKK3,Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),GO:0003677; GO:0006281; GO:0003950; GO:0008219; GO:0005737; GO:0019899; GO:0006954; GO:0005634; GO:0006471; GO:0042493; GO:0030529; GO:0005876; GO:0006810,DNA binding; DNA repair; NAD+ ADP-ribosyltransferase activity; cell death; cytoplasm; enzyme binding; inflammatory response; nucleus; protein ADP-ribosylation; response to drug; ribonucleoprotein complex; spindle microtubule; transport,PF00533;PF00644;PF08487;PF00092;,,,,,,,,,PARP4_HUMAN,Homo sapiens (Human),cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810] comp134574_c4_seq1,1924,44.6985,0.27342114,22,37,,2.00E-153,Q9UKK3,Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),GO:0003677; GO:0006281; GO:0003950; GO:0008219; GO:0005737; GO:0019899; GO:0006954; GO:0005634; GO:0006471; GO:0042493; GO:0030529; GO:0005876; GO:0006810,DNA binding; DNA repair; NAD+ ADP-ribosyltransferase activity; cell death; cytoplasm; enzyme binding; inflammatory response; nucleus; protein ADP-ribosylation; response to drug; ribonucleoprotein complex; spindle microtubule; transport,PF00533;PF00644;PF08487;PF00092;,5.00E-112,CHOYP_LOC100373327.8.13,,,,,,,PARP4_HUMAN,Homo sapiens (Human),cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810] comp134574_c4_seq2,1546,43.6611,0.24505,0,0,,1.00E-27,C7G046,von Willebrand factor A domain-containing protein DDB_G0286969,von Willebrand factor A domain-containing protein DDB_G0286969,GO:0003723,RNA binding,PF02847;PF02854;PF08487;PF13768;,,,,,,,,,Y6969_DICDI,Dictyostelium discoideum (Slime mold), comp134574_c4_seq3,616,43.6688,0.2064241,0,0,,,,,,,,,2.00E-34,CHOYP_CAOG_03714.1.1,,,,,,,,, comp134576_c0_seq1,1463,41.9686,0.74211788,8,16,,5.00E-70,Q7SXF6,Cysteine-rich with EGF-like domain protein 2,Cysteine-rich with EGF-like domain protein 2,GO:0005509; GO:0005783; GO:0005576,calcium ion binding; endoplasmic reticulum; extracellular region,PF11938;PF07645;,,,,,,,,,CREL2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp134576_c0_seq2,1372,41.691,0.76814299,5,45,,8.00E-70,Q5EA46,Cysteine-rich with EGF-like domain protein 1,Cysteine-rich with EGF-like domain protein 1,GO:0005509; GO:0016021,calcium ion binding; integral to membrane,PF11938;PF07645;,,,,,,,,,CREL1_BOVIN,Bos taurus (Bovine), comp134579_c0_seq2,1494,43.909,0.41218656,25,20,,7.00E-132,Q9BZE2,tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3),tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3),GO:0003723; GO:0005634; GO:0009982; GO:0031119,RNA binding; nucleus; pseudouridine synthase activity; tRNA pseudouridine synthesis,PF01416;,5.00E-124,CHOYP_PUS3.1.1,,,,,,,PUS3_HUMAN,Homo sapiens (Human),tRNA pseudouridine synthesis [GO:0031119] comp134581_c0_seq2,1392,40.5172,0.51055332,4,7,,2.00E-66,Q5FVJ6,Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog),Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog),GO:0045444; GO:0030176; GO:0016042; GO:0034389; GO:0019915; GO:0050995,fat cell differentiation; integral to endoplasmic reticulum membrane; lipid catabolic process; lipid particle organization; lipid storage; negative regulation of lipid catabolic process,PF06775;,3.00E-18,CHOYP_LOC100699837.1.1,,,,,,,BSCL2_RAT,Rattus norvegicus (Rat),fat cell differentiation [GO:0045444]; lipid catabolic process [GO:0016042]; lipid particle organization [GO:0034389]; lipid storage [GO:0019915]; negative regulation of lipid catabolic process [GO:0050995] comp134581_c2_seq2,1714,43.9323,0.53699137,111,86,,3.00E-71,A7Z035,Clathrin interactor 1 (Epsin-4),Clathrin interactor 1 (Epsin-4),GO:0005798; GO:0030136; GO:0006897; GO:0008289; GO:0016020; GO:0048471; GO:0005802,Golgi-associated vesicle; clathrin-coated vesicle; endocytosis; lipid binding; membrane; perinuclear region of cytoplasm; trans-Golgi network,PF01417;,5.00E-74,CHOYP_EPN4.1.3,,,,,,,EPN4_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897] comp134586_c0_seq1,2457,43.8339,1.01562506,61,457,,3.00E-10,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp134586_c0_seq2,1780,40.3933,1.06931136,27,295,,5.00E-10,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp134588_c0_seq2,3799,35.1408,0.46337628,541,374,,1.00E-48,Q28XE2,Acidic leucine-rich nuclear phosphoprotein 32 family member A,Acidic leucine-rich nuclear phosphoprotein 32 family member A,GO:0005783; GO:0006913; GO:0005634; GO:0048471,endoplasmic reticulum; nucleocytoplasmic transport; nucleus; perinuclear region of cytoplasm,,8.00E-12,CHOYP_ISCW_ISCW021350.1.1,,,,,,,AN32A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),nucleocytoplasmic transport [GO:0006913] comp134588_c0_seq4,948,39.6624,0.65334723,0,0,,9.00E-53,Q28XE2,Acidic leucine-rich nuclear phosphoprotein 32 family member A,Acidic leucine-rich nuclear phosphoprotein 32 family member A,GO:0005783; GO:0006913; GO:0005634; GO:0048471,endoplasmic reticulum; nucleocytoplasmic transport; nucleus; perinuclear region of cytoplasm,,,,,,,,,,AN32A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),nucleocytoplasmic transport [GO:0006913] comp134590_c0_seq1,2187,36.7627,0.33286011,44,147,,,,,,,,,3.00E-84,CHOYP_BRAFLDRAFT_126791.1.1,,,,,,,,, comp134590_c0_seq3,1905,35.5381,0.32041558,1,0,,,,,,,,,6.00E-48,CHOYP_BRAFLDRAFT_126791.1.1,,,,,,,,, comp134593_c0_seq1,2174,37.7185,1.03896126,4379,3977,,6.00E-96,Q27433,Mechanosensory protein 2,Mechanosensory protein 2,GO:0016021; GO:0007638; GO:0032589,integral to membrane; mechanosensory behavior; neuron projection membrane,PF01145;,2.00E-110,CHOYP_MEC2.4.4,2.00E-135,ruditapes_c11694,,,,,MEC2_CAEEL,Caenorhabditis elegans,mechanosensory behavior [GO:0007638]; response to mechanical stimulus [GO:0009612] comp134596_c0_seq1,217,24.8848,0,3,14,,,,,,,,,,,4.00E-11,ruditapes_c30227,,,,,,, comp134598_c0_seq3,523,44.1683,1.00506735,0,47,,4.00E-14,P37059,Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),GO:0047006; GO:0005789; GO:0004303; GO:0001701; GO:0016021; GO:0001890; GO:0032526; GO:0006694; GO:0047035,"17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; endoplasmic reticulum membrane; estradiol 17-beta-dehydrogenase activity; in utero embryonic development; integral to membrane; placenta development; response to retinoic acid; steroid biosynthetic process; testosterone dehydrogenase (NAD+) activity",PF00106;,,,,,,,,,DHB2_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694] comp134598_c0_seq4,621,44.4444,1.05451929,8,30,,1.00E-39,P55006,Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase type III) (RODH III),Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase type III) (RODH III),GO:0005783; GO:0004745; GO:0042572,endoplasmic reticulum; retinol dehydrogenase activity; retinol metabolic process,PF00106;,,,,,,,,,RDH7_RAT,Rattus norvegicus (Rat),retinol metabolic process [GO:0042572] comp134605_c0_seq1,1455,40.6873,0.49881828,0,25,,2.00E-10,Q8BXX2,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_MOUSE,Mus musculus (Mouse),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp134605_c0_seq4,1398,41.1302,0.50784112,0,31,,2.00E-10,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp134605_c0_seq7,495,32.9293,0.52273625,1,3,,3.00E-12,Q8BXX2,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_MOUSE,Mus musculus (Mouse),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp134606_c0_seq1,1271,41.6994,0.46086985,54,142,,1.00E-47,Q8BG18,N-terminal EF-hand calcium-binding protein 1 (EF-hand calcium-binding protein 1),N-terminal EF-hand calcium-binding protein 1 (EF-hand calcium-binding protein 1),GO:0005509; GO:0005737; GO:0005634,calcium ion binding; cytoplasm; nucleus,PF03992;PF13833;,2.00E-39,CHOYP_BRAFLDRAFT_124536.1.2,,,,,,,NECA1_MOUSE,Mus musculus (Mouse), comp134606_c0_seq2,259,41.3127,0.73759965,0,0,,,,,,,,,1.00E-26,CHOYP_BRAFLDRAFT_124536.1.2,,,,,,,,, comp134609_c0_seq3,798,44.1103,0.49237882,2,0,,2.00E-46,P20488,Synaptophysin (Major synaptic vesicle protein p38),Synaptophysin (Major synaptic vesicle protein p38),GO:0030054; GO:0006897; GO:0016021; GO:0043005; GO:2000474; GO:0030672; GO:0005215,cell junction; endocytosis; integral to membrane; neuron projection; regulation of opioid receptor signaling pathway; synaptic vesicle membrane; transporter activity,PF01284;,,,,,,,,,SYPH_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; negative regulation of exocytosis [GO:0045920]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of opioid receptor signaling pathway [GO:2000474] comp134611_c0_seq2,583,35.8491,0.27127542,0,76,,,,,,,,,3.00E-26,CHOYP_LOC100378414.1.1,,,,,,,,, comp134611_c0_seq3,1156,37.9758,0.45885899,116,659,,3.00E-92,B4M375,"NFU1 iron-sulfur cluster scaffold homolog, mitochondrial","NFU1 iron-sulfur cluster scaffold homolog, mitochondrial",GO:0005506; GO:0016226; GO:0051536; GO:0005739,iron ion binding; iron-sulfur cluster assembly; iron-sulfur cluster binding; mitochondrion,PF08712;PF01106;,5.00E-65,CHOYP_LOC100378414.1.1,2.00E-50,ruditapes_c27351,,,,,NFU1_DROVI,Drosophila virilis (Fruit fly),iron-sulfur cluster assembly [GO:0016226] comp134612_c0_seq1,544,43.75,0.43018228,15,63,,6.00E-18,Q5R4C9,Nuclear receptor-binding factor 2 (NRBF-2),Nuclear receptor-binding factor 2 (NRBF-2),GO:0005737; GO:0005634; GO:0006355; GO:0006351,"cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08961;PF17169;,,,,,,,,,NRBF2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"autophagy [GO:0006914]; regulation of autophagy [GO:0010506]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]" comp134614_c0_seq1,1195,40.7531,1.15085502,2527,6,male>female,7.00E-34,Q6IMH0,"Testis, prostate and placenta-expressed protein","Testis, prostate and placenta-expressed protein",,,,5.00E-65,CHOYP_LOC100179516.2.2,,,,,,,TEPP_MOUSE,Mus musculus (Mouse), comp134615_c0_seq2,418,43.3014,1.02320488,0,0,,2.00E-26,Q9QY61,Iroquois-class homeodomain protein IRX-4 (Homeodomain protein IRXA3) (Iroquois homeobox protein 4),Iroquois-class homeodomain protein IRX-4 (Homeodomain protein IRXA3) (Iroquois homeobox protein 4),GO:0030154; GO:0007507; GO:0005634; GO:0006357; GO:0043565; GO:0003700; GO:0005667,cell differentiation; heart development; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex,PF05920;,6.00E-27,CHOYP_IRO.2.4,,,,,,,IRX4_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; establishment of organ orientation [GO:0048561]; heart development [GO:0007507]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp134619_c0_seq1,2207,43.4073,0.47179497,699,115,,4.00E-165,Q11179,Putative serine/threonine-protein kinase C05D10.2 (EC 2.7.11.24),Putative serine/threonine-protein kinase C05D10.2 (EC 2.7.11.24),GO:0005524; GO:0004707; GO:0000165,ATP binding; MAP kinase activity; MAPK cascade,PF00069;,0,CHOYP_BRAFLDRAFT_88155.1.1,,,,,,,YPC2_CAEEL,Caenorhabditis elegans, comp134624_c0_seq1,1401,37.1163,0.37531809,302,1306,,7.00E-29,Q99622,Protein C10,Protein C10,GO:0005737,cytoplasm,PF14974;,6.00E-21,CHOYP_LOC101357837.1.1,,,,,,,C10_HUMAN,Homo sapiens (Human), comp134625_c0_seq1,2217,38.4754,0.51511241,236,920,,3.00E-66,Q6FQU5,ATP-dependent RNA helicase DHH1 (EC 3.6.4.13),ATP-dependent RNA helicase DHH1 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0000932; GO:0006397; GO:0051028; GO:0006417,ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasmic mRNA processing body; mRNA processing; mRNA transport; regulation of translation,PF00270;PF00271;,1.00E-158,CHOYP_LOC101067857.1.1,,,,,,,DHH1_CANGA,Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata),cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of translational elongation [GO:0045900]; stress granule assembly [GO:0034063] comp134625_c0_seq2,2203,38.5384,0.5163609,190,412,,0,Q5WR10,Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (DEAD box protein UAP56),Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (DEAD box protein UAP56),GO:0005524; GO:0004004; GO:0010501; GO:0030621; GO:0005687; GO:0017070; GO:0005688; GO:0005737; GO:0046784; GO:0016607; GO:0005681; GO:0000245; GO:0000346,ATP binding; ATP-dependent RNA helicase activity; RNA secondary structure unwinding; U4 snRNA binding; U4 snRNP; U6 snRNA binding; U6 snRNP; cytoplasm; intronless viral mRNA export from host nucleus; nuclear speck; spliceosomal complex; spliceosomal complex assembly; transcription export complex,PF00270;PF00271;,0,CHOYP_DX39B.2.3,2.00E-115,ruditapes2_c1362,,,,,DX39B_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),"cellular response to DNA damage stimulus [GO:0006974]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]" comp134627_c0_seq1,353,43.0595,0.73559032,16,18,,1.00E-19,Q8C008,Double zinc ribbon and ankyrin repeat-containing protein 1,Double zinc ribbon and ankyrin repeat-containing protein 1,GO:0008270,zinc ion binding,PF12773;PF13287;,,,,,,,,,DZAN1_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779] comp134627_c1_seq2,1313,44.8591,0.40907228,72,198,,2.00E-69,Q4R5L5,Annexin A7 (Annexin VII) (Annexin-7),Annexin A7 (Annexin VII) (Annexin-7),GO:0005509; GO:0005544,calcium ion binding; calcium-dependent phospholipid binding,PF00191;,1.00E-73,CHOYP_ANXA6.1.2,,,,,,,ANXA7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp134628_c0_seq1,2704,40.8654,0.93066818,155,1016,,2.00E-108,Q66IY8,Interferon regulatory factor 2-binding protein-like A (Enhanced at puberty protein 1 homolog A),Interferon regulatory factor 2-binding protein-like A (Enhanced at puberty protein 1 homolog A),GO:0046872; GO:0005634,metal ion binding; nucleus,PF11261;,9.00E-41,CHOYP_I2BLB.1.1,,,,,,,I2BLA_XENLA,Xenopus laevis (African clawed frog), comp134631_c0_seq1,2130,37.7934,0.89462656,5,49,,4.00E-41,P23819,"Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)","Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)",GO:0004971; GO:0032281; GO:0030054; GO:0005783; GO:0005789; GO:0005234; GO:0015277; GO:0043005; GO:0045211; GO:0007268; GO:0008021,alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; cell junction; endoplasmic reticulum; endoplasmic reticulum membrane; extracellular-glutamate-gated ion channel activity; kainate selective glutamate receptor activity; neuron projection; postsynaptic membrane; synaptic transmission; synaptic vesicle,PF01094;PF00060;PF10613;,,,,,,,,,GRIA2_MOUSE,Mus musculus (Mouse),chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235] comp134631_c0_seq2,1937,36.7579,0.90238441,4,0,,4.00E-19,Q91755,"Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)","Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)",GO:0030054; GO:0005234; GO:0016021; GO:0004970; GO:0035235; GO:0045211,cell junction; extracellular-glutamate-gated ion channel activity; integral to membrane; ionotropic glutamate receptor activity; ionotropic glutamate receptor signaling pathway; postsynaptic membrane,PF00060;,,,,,,,,,GRIK2_XENLA,Xenopus laevis (African clawed frog), comp134631_c0_seq3,1929,37.1695,0.90140606,0,0,,4.00E-27,P19491,"Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)","Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)",GO:0030165; GO:0004971; GO:0032281; GO:0032279; GO:0030054; GO:0009986; GO:0032839; GO:0043198; GO:0043197; GO:0005789; GO:0045184; GO:0005234; GO:0030426; GO:0015277; GO:0043204; GO:0050806; GO:0014069; GO:0045211; GO:0042734; GO:0051262; GO:0031623; GO:0001919; GO:0051966; GO:0060992; GO:0010226; GO:0007268; GO:0030672; GO:0043195,"PDZ domain binding; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; asymmetric synapse; cell junction; cell surface; dendrite cytoplasm; dendritic shaft; dendritic spine; endoplasmic reticulum membrane; establishment of protein localization; extracellular-glutamate-gated ion channel activity; growth cone; kainate selective glutamate receptor activity; perikaryon; positive regulation of synaptic transmission; postsynaptic density; postsynaptic membrane; presynaptic membrane; protein tetramerization; receptor internalization; regulation of receptor recycling; regulation of synaptic transmission, glutamatergic; response to fungicide; response to lithium ion; synaptic transmission; synaptic vesicle membrane; terminal bouton",PF01094;PF00060;PF10613;,,,,,,,,,GRIA2_RAT,Rattus norvegicus (Rat),"chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]" comp134632_c1_seq1,993,40.9869,0.4342512,105,466,,1.00E-70,Q5VWZ2,Lysophospholipase-like protein 1 (EC 3.1.2.-),Lysophospholipase-like protein 1 (EC 3.1.2.-),GO:0005829; GO:0004622; GO:0042997; GO:0002084,cytosol; lysophospholipase activity; negative regulation of Golgi to plasma membrane protein transport; protein depalmitoylation,PF02230;,,,,,,,,,LYPL1_HUMAN,Homo sapiens (Human),protein depalmitoylation [GO:0002084] comp134643_c0_seq1,1305,39.2337,0.57990265,9310,28703,,7.00E-34,Q94516,"ATP synthase subunit b, mitochondrial (ATPase subunit b) (FO-ATP synthase subunit b)","ATP synthase subunit b, mitochondrial (ATPase subunit b) (FO-ATP synthase subunit b)",GO:0015986; GO:0005811; GO:0000276; GO:0006909; GO:0046933,"ATP synthesis coupled proton transport; lipid particle; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); phagocytosis; proton-transporting ATP synthase activity, rotational mechanism",PF05405;,,,1.00E-13,ruditapes_lrc34584,,,,,AT5F1_DROME,Drosophila melanogaster (Fruit fly),ATP synthesis coupled proton transport [GO:0015986]; phagocytosis [GO:0006909]; proton transport [GO:0015992] comp134645_c0_seq1,1024,46.0938,0.86895826,121,156,,2.00E-59,Q66H59,N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase),N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase),GO:0019262; GO:0008747; GO:0005975; GO:0005737,N-acetylneuraminate catabolic process; N-acetylneuraminate lyase activity; carbohydrate metabolic process; cytoplasm,PF00701;,,,,,,,,,NPL_RAT,Rattus norvegicus (Rat),carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262] comp134653_c1_seq1,784,45.2806,0.52779109,28,103,,6.00E-85,Q66JG1,DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2),DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2),GO:0003677; GO:0006281; GO:0005634; GO:0016567,DNA binding; DNA repair; nucleus; protein ubiquitination,PF00400;,2.00E-36,CHOYP_LOC100554400.1.1,,,,,,,DDB2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),DNA repair [GO:0006281]; protein ubiquitination [GO:0016567] comp134660_c0_seq1,1804,35.3659,1.35146093,1004,4706,,2.00E-37,Q9BLG0,Troponin C (TN-C),Troponin C (TN-C),GO:0005509,calcium ion binding,PF13499;,7.00E-28,CHOYP_TNNC.1.1,6.00E-14,ruditapes_c8079,,,,,TNNC_TODPA,Todarodes pacificus (Japanese flying squid) (Ommastrephes pacificus), comp134662_c0_seq1,1250,45.2,0.87954859,59,166,,4.00E-59,P15589,Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),GO:0005789; GO:0007565; GO:0016021; GO:0007611; GO:0046872; GO:0005635; GO:0008284; GO:0043627; GO:0009268; GO:0043434; GO:0043588; GO:0008202; GO:0004773,endoplasmic reticulum membrane; female pregnancy; integral to membrane; learning or memory; metal ion binding; nuclear envelope; positive regulation of cell proliferation; response to estrogen stimulus; response to pH; response to peptide hormone stimulus; skin development; steroid metabolic process; steryl-sulfatase activity,PF00884;,,,,,,,,,STS_RAT,Rattus norvegicus (Rat),female pregnancy [GO:0007565]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; response to estrogen [GO:0043627]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid metabolic process [GO:0008202] comp134669_c0_seq1,990,44.8485,0.43501299,75,106,,1.00E-85,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,1.00E-22,CHOYP_BRAFLDRAFT_74063.2.5,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp134670_c0_seq1,1175,38.8936,0.94021362,140,1391,,1.00E-36,Q96LD1,Zeta-sarcoglycan (Zeta-SG) (ZSG1),Zeta-sarcoglycan (Zeta-SG) (ZSG1),GO:0005737; GO:0005856; GO:0016021; GO:0061024; GO:0046716; GO:0055001; GO:0016012; GO:0042383,cytoplasm; cytoskeleton; integral to membrane; membrane organization; muscle cell cellular homeostasis; muscle cell development; sarcoglycan complex; sarcolemma,PF04790;,,,4.00E-32,ruditapes_c8475,,,,,SGCZ_HUMAN,Homo sapiens (Human),cardiac muscle tissue development [GO:0048738]; heart contraction [GO:0060047]; membrane organization [GO:0061024]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517] comp134672_c0_seq2,858,48.951,0.54559551,55,35,,2.00E-95,Q9EQW7,Kinesin-like protein KIF13A,Kinesin-like protein KIF13A,GO:0005524; GO:0000139; GO:0043001; GO:0035459; GO:0005813; GO:0000910; GO:0010008; GO:0008333; GO:0005871; GO:0032438; GO:0005874; GO:0003777; GO:0030496; GO:0072383; GO:0032588,ATP binding; Golgi membrane; Golgi to plasma membrane protein transport; cargo loading into vesicle; centrosome; cytokinesis; endosome membrane; endosome to lysosome transport; kinesin complex; melanosome organization; microtubule; microtubule motor activity; midbody; plus-end-directed vesicle transport along microtubule; trans-Golgi network membrane,PF12473;PF12423;PF00225;PF16183;,2.00E-44,CHOYP_LOC100881280.1.1,,,,,,,KI13A_MOUSE,Mus musculus (Mouse),cargo loading into vesicle [GO:0035459]; cytokinesis [GO:0000910]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; plus-end-directed vesicle transport along microtubule [GO:0072383] comp134672_c0_seq4,1122,41.0873,0.49045181,15,51,,1.00E-14,Q8CI96,CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),,,PF12796;PF01302;,,,,,,,,,CLIP4_MOUSE,Mus musculus (Mouse), comp134672_c0_seq5,941,47.1838,0.53429466,34,22,,2.00E-83,Q9NQT8,Kinesin-like protein KIF13B (Kinesin-like protein GAKIN),Kinesin-like protein KIF13B (Kinesin-like protein GAKIN),GO:0071889; GO:0005524; GO:0042110; GO:0030424; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0006605; GO:0050770; GO:0007165,14-3-3 protein binding; ATP binding; T cell activation; axon; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; protein targeting; regulation of axonogenesis; signal transduction,PF01302;PF12473;PF00498;PF12423;PF00225;PF16183;,,,,,,,,,KI13B_HUMAN,Homo sapiens (Human),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; protein targeting [GO:0006605]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]; T cell activation [GO:0042110] comp134677_c0_seq1,2560,38.1641,0.44051442,110,370,,3.00E-12,Q3V1H1,Cytoskeleton-associated protein 2,Cytoskeleton-associated protein 2,GO:0006915; GO:0005813; GO:0005881; GO:0000281; GO:0007026; GO:0045944; GO:0000922,apoptotic process; centrosome; cytoplasmic microtubule; mitotic cytokinesis; negative regulation of microtubule depolymerization; positive regulation of transcription from RNA polymerase II promoter; spindle pole,PF15297;,,,,,,,,,CKAP2_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; negative regulation of microtubule depolymerization [GO:0007026]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp134678_c2_seq1,1603,39.8004,1.20220954,62,342,,5.00E-15,Q8NCG5,Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2),Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2),GO:0001517; GO:0006044; GO:0005975; GO:0007155; GO:0007267; GO:0006928; GO:0006955; GO:0006954; GO:0016021; GO:0031228; GO:0050901; GO:0006477; GO:0005802,N-acetylglucosamine 6-O-sulfotransferase activity; N-acetylglucosamine metabolic process; carbohydrate metabolic process; cell adhesion; cell-cell signaling; cellular component movement; immune response; inflammatory response; integral to membrane; intrinsic to Golgi membrane; leukocyte tethering or rolling; protein sulfation; trans-Golgi network,PF00685;,,,,,,,,,CHST4_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; immune response [GO:0006955]; inflammatory response [GO:0006954]; movement of cell or subcellular component [GO:0006928]; N-acetylglucosamine metabolic process [GO:0006044]; O-glycan processing [GO:0016266]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] comp134681_c1_seq1,1915,48.4073,0.54206997,169,38,,5.00E-120,Q9QYP0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity,PF00431;PF12947;PF07645;PF00053;PF01437;,,,,,,,,,MEGF8_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp134681_c2_seq1,883,48.1314,0.56772152,56,15,,1.00E-18,Q6A051,Attractin-like protein 1,Attractin-like protein 1,GO:0007186; GO:0030246; GO:0016021; GO:0007275; GO:0005886; GO:0004872,G-protein coupled receptor signaling pathway; carbohydrate binding; integral to membrane; multicellular organismal development; plasma membrane; receptor activity,PF00431;PF07974;PF01344;PF00053;PF00059;PF01437;,,,,,,,,,ATRN1_MOUSE,Mus musculus (Mouse),G-protein coupled receptor signaling pathway [GO:0007186] comp134681_c3_seq1,501,43.7126,0.59059059,14,19,,9.00E-08,Q8W4K1,tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (EC 2.1.1.282); tRNA wybutosine-synthesizing protein 2 homolog (EC 2.5.1.-)],tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)],GO:0008168; GO:0031591,methyltransferase activity; wybutosine biosynthetic process,PF01344;PF02475;PF02676;,,,,,,,,,TYW23_ARATH,Arabidopsis thaliana (Mouse-ear cress),wybutosine biosynthetic process [GO:0031591] comp134683_c0_seq1,1459,39.9589,0.36630054,7,9,,,,,,,,,,,8.00E-49,ruditapes_c9946,,,,,,, comp134683_c0_seq3,1444,39.8892,0.39096843,13,38,,1.00E-06,Q5RKH6,Protein OS-9,Protein OS-9,GO:0030433; GO:0005788; GO:0001948; GO:0006621; GO:0006605; GO:0042787; GO:0034976,ER-associated protein catabolic process; endoplasmic reticulum lumen; glycoprotein binding; protein retention in ER lumen; protein targeting; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to endoplasmic reticulum stress,PF07915;,,,,,,,,,OS9_RAT,Rattus norvegicus (Rat),"ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein retention in ER lumen [GO:0006621]; protein targeting [GO:0006605]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; retrograde protein transport, ER to cytosol [GO:0030970]" comp134690_c0_seq1,463,47.3002,1.00634437,6,897,female>male,1.00E-22,Q01490,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B),GO:0005788; GO:0042277; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum lumen; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,2.00E-27,CHOYP_LOC100374495.1.1,,,,,,,PPIB_ORPSP,Orpinomyces sp. (strain PC-2),protein folding [GO:0006457] comp134690_c1_seq1,658,34.6505,1.06692097,4,1020,female>male,6.00E-16,P34887,Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase),Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase),GO:0005737; GO:0042277; GO:0003755; GO:0006457; GO:0000413,cytoplasm; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,4.00E-38,CHOYP_PPIB.3.4,4.00E-23,ruditapes2_c789,,,,,CYPH_ALLCE,Allium cepa (Onion),protein folding [GO:0006457] comp134691_c0_seq1,1017,41.6912,0.74948202,93,1188,,1.00E-51,P78417,Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),GO:0019852; GO:0071243; GO:0005829; GO:0045174; GO:1901687; GO:0004364; GO:0050610; GO:0060315; GO:0060316; GO:0014810; GO:0010881; GO:0042178,L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; cytosol; glutathione dehydrogenase (ascorbate) activity; glutathione derivative biosynthetic process; glutathione transferase activity; methylarsonate reductase activity; negative regulation of ryanodine-sensitive calcium-release channel activity; positive regulation of ryanodine-sensitive calcium-release channel activity; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; xenobiotic catabolic process,PF14497;PF13417;,6.00E-32,CHOYP_GSTO1.1.2,,,,,,,GSTO1_HUMAN,Homo sapiens (Human),cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178] comp134692_c0_seq1,2325,38.7527,0.46576366,2894,18667,,0,P00508,"Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Transaminase A)","Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Transaminase A)",GO:0006103; GO:0004069; GO:0080130; GO:0006531; GO:0006094; GO:0006536; GO:0016212; GO:0005759; GO:0030170,2-oxoglutarate metabolic process; L-aspartate:2-oxoglutarate aminotransferase activity; L-phenylalanine:2-oxoglutarate aminotransferase activity; aspartate metabolic process; gluconeogenesis; glutamate metabolic process; kynurenine-oxoglutarate transaminase activity; mitochondrial matrix; pyridoxal phosphate binding,PF00155;,2.00E-180,CHOYP_AATM.1.1,,,,,,,AATM_CHICK,Gallus gallus (Chicken),2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536] comp134693_c0_seq2,3000,43.9333,0.30473124,0,0,,0,Q28205,Tubulin-specific chaperone D (Beta-tubulin cofactor D) (Tubulin-folding cofactor D),Tubulin-specific chaperone D (Beta-tubulin cofactor D) (Tubulin-folding cofactor D),GO:0005096; GO:0005912; GO:0034333; GO:0048487; GO:0005829; GO:0016328; GO:0010812; GO:0031115; GO:0007023; GO:0005923; GO:0070830,GTPase activator activity; adherens junction; adherens junction assembly; beta-tubulin binding; cytosol; lateral plasma membrane; negative regulation of cell-substrate adhesion; negative regulation of microtubule polymerization; post-chaperonin tubulin folding pathway; tight junction; tight junction assembly,PF12612;,,,,,,,,,TBCD_BOVIN,Bos taurus (Bovine),adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] comp134693_c0_seq3,2971,43.8573,0.30169675,0,0,,5.00E-67,Q55G93,Tubulin-specific chaperone D (Tubulin-folding cofactor D),Tubulin-specific chaperone D (Tubulin-folding cofactor D),,,PF12612;,5.00E-165,CHOYP_TBCD.1.2,,,,,,,TBCD_DICDI,Dictyostelium discoideum (Slime mold),microtubule cytoskeleton organization [GO:0000226]; positive regulation of GTPase activity [GO:0043547]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] comp134693_c0_seq5,3698,43.6723,0.3649849,43,31,,0,Q9BTW9,Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D),Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D),GO:0051084; GO:0005096; GO:0005912; GO:0034333; GO:0048487; GO:0051087; GO:0005737; GO:0016328; GO:0005874; GO:0010812; GO:0031115; GO:0007023; GO:0005923; GO:0070830,'de novo' posttranslational protein folding; GTPase activator activity; adherens junction; adherens junction assembly; beta-tubulin binding; chaperone binding; cytoplasm; lateral plasma membrane; microtubule; negative regulation of cell-substrate adhesion; negative regulation of microtubule polymerization; post-chaperonin tubulin folding pathway; tight junction; tight junction assembly,PF12612;,0,CHOYP_TBCD.1.2,,,,,,,TBCD_HUMAN,Homo sapiens (Human),adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] comp134701_c1_seq1,1819,39.2523,0.78563436,2,0,,1.00E-24,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp134701_c1_seq2,2236,40.6977,0.85366849,7,3,,1.00E-14,Q6UXC1,Apical endosomal glycoprotein (MAM domain-containing protein 4),Apical endosomal glycoprotein (MAM domain-containing protein 4),GO:0016021; GO:0015031,integral to membrane; protein transport,PF00057;PF00629;,,,,,,,,,AEGP_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp134701_c1_seq3,2196,39.9818,0.85499263,1,8,,1.00E-25,P85171,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,,,,,,,,,MDGA1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp134705_c0_seq1,484,43.595,0.91608594,2,53,,9.00E-14,O69787,Choline-sulfatase (EC 3.1.6.6),Choline-sulfatase (EC 3.1.6.6),GO:0042425; GO:0047753; GO:0046872,choline biosynthetic process; choline-sulfatase activity; metal ion binding,PF12411;PF00884;,,,1.00E-16,ruditapes_c11827,,,,,BETC_RHIME,Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti),choline biosynthetic process [GO:0042425] comp134705_c2_seq1,494,42.1053,0.96108012,1,45,,6.00E-34,P22304,Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain],Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain],GO:0005975; GO:0030207; GO:0004423; GO:0043202; GO:0046872,carbohydrate metabolic process; chondroitin sulfate catabolic process; iduronate-2-sulfatase activity; lysosomal lumen; metal ion binding,PF00884;,,,,,,,,,IDS_HUMAN,Homo sapiens (Human),chondroitin sulfate catabolic process [GO:0030207]; glycosaminoglycan catabolic process [GO:0006027] comp134706_c0_seq1,1315,41.1407,0.43649656,520,2081,,,,,,,,,1.00E-150,CHOYP_BRAFLDRAFT_279923.1.1,6.00E-63,ruditapes_c12546,,,,,,, comp134706_c0_seq2,1356,41.0029,0.44346429,149,1418,,3.00E-163,P84169,26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5),26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5),GO:0022624,proteasome accessory complex,PF01399;,,,,,,,,,PSD13_CHICK,Gallus gallus (Chicken),proteasome assembly [GO:0043248]; ubiquitin-dependent protein catabolic process [GO:0006511] comp134708_c0_seq1,1186,33.4739,0.61034597,70,235,,2.00E-28,Q9CQT9,Uncharacterized protein C20orf24 homolog,Uncharacterized protein C20orf24 homolog,GO:0005739,mitochondrion,PF07019;,5.00E-34,CHOYP_LOC100698115.1.1,,,,,,,CT024_MOUSE,Mus musculus (Mouse), comp134710_c1_seq1,775,41.4194,0.9158879,56,473,,1.00E-40,P50226,Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2),Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2),GO:0050427; GO:0009309; GO:0004062; GO:0006584; GO:0005829; GO:0047894; GO:0018958; GO:0008202; GO:0051923; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine biosynthetic process; aryl sulfotransferase activity; catecholamine metabolic process; cytosol; flavonol 3-sulfotransferase activity; phenol-containing compound metabolic process; steroid metabolic process; sulfation; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1A2_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine biosynthetic process [GO:0009309]; catecholamine metabolic process [GO:0006584]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805] comp134711_c0_seq1,1750,46.1143,0.37220394,110,156,,1.00E-59,A2A870,Fas-binding factor 1 (FBF-1),Fas-binding factor 1 (FBF-1),GO:0043297; GO:0030054; GO:0005814; GO:0042384; GO:0090162; GO:0000922,apical junction assembly; cell junction; centriole; cilium assembly; establishment of epithelial cell polarity; spindle pole,,2.00E-54,CHOYP_BRAFLDRAFT_64593.1.1,,,,,,,FBF1_MOUSE,Mus musculus (Mouse),apical junction assembly [GO:0043297]; cilium assembly [GO:0042384]; establishment of epithelial cell polarity [GO:0090162] comp134716_c0_seq1,1715,44.9563,0.36989248,17,0,,2.00E-156,Q9NRP7,Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog),Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog),GO:0005524; GO:0007420; GO:0042384; GO:0005737; GO:0003351; GO:0000287; GO:0005634; GO:0007228; GO:0045880; GO:0009791; GO:0004674; GO:0008134,ATP binding; brain development; cilium assembly; cytoplasm; epithelial cilium movement; magnesium ion binding; nucleus; positive regulation of hh target transcription factor activity; positive regulation of smoothened signaling pathway; post-embryonic development; protein serine/threonine kinase activity; transcription factor binding,PF00069;,0,CHOYP_STK36.1.1,,,,,,,STK36_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090] comp134716_c0_seq11,690,48.5507,0.34644107,0,11,,3.00E-21,Q69ZM6,Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog),Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog),GO:0005524; GO:0007420; GO:0042384; GO:0005737; GO:0003351; GO:0046872; GO:0005634; GO:0007228; GO:0045880; GO:0009791; GO:0004674; GO:0008134,ATP binding; brain development; cilium assembly; cytoplasm; epithelial cilium movement; metal ion binding; nucleus; positive regulation of hh target transcription factor activity; positive regulation of smoothened signaling pathway; post-embryonic development; protein serine/threonine kinase activity; transcription factor binding,PF00069;,2.00E-119,CHOYP_LOC100372921.2.2,,,,,,,STK36_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090] comp134716_c0_seq4,1520,43.6842,0.44247694,13,0,,6.00E-118,Q2QAV0,Serine/threonine-protein kinase TIO (EC 2.7.11.1) (Fused homolog) (AtFUSED) (Protein TWO-IN-ONE) (AtTIO),Serine/threonine-protein kinase TIO (EC 2.7.11.1) (Fused homolog) (AtFUSED) (Protein TWO-IN-ONE) (AtTIO),GO:0005524; GO:0000911; GO:0005856; GO:0009558; GO:0009524; GO:0004674,ATP binding; cytokinesis by cell plate formation; cytoskeleton; embryo sac cellularization; phragmoplast; protein serine/threonine kinase activity,PF00069;,0,CHOYP_STK36.1.1,,,,,,,TIO_ARATH,Arabidopsis thaliana (Mouse-ear cress),cytokinesis by cell plate formation [GO:0000911]; embryo sac cellularization [GO:0009558] comp134717_c0_seq1,1647,36.8549,0.48938669,2147,41,,9.00E-28,P36425,Sperm surface protein Sp17 (Sperm autoantigenic protein 17),Sperm surface protein Sp17 (Sperm autoantigenic protein 17),GO:0007339; GO:0001539; GO:0005737; GO:0016020; GO:0031514; GO:0072372,binding of sperm to zona pellucida; ciliary or bacterial-type flagellar motility; cytoplasm; membrane; motile cilium; primary cilium,PF00612;PF02197;,5.00E-54,CHOYP_LOC100373522.4.5,4.00E-136,ruditapes_c14289,,,,,SP17_RABIT,Oryctolagus cuniculus (Rabbit),binding of sperm to zona pellucida [GO:0007339] comp134722_c0_seq1,1236,33.1715,0.58757538,40,106,,,,,,,,,2.00E-89,CHOYP_BRAFLDRAFT_234234.1.2,,,,,,,,, comp134722_c0_seq2,1247,33.1195,0.61660119,20,99,,7.00E-84,Q5F359,Trafficking protein particle complex subunit 5,Trafficking protein particle complex subunit 5,GO:0005794; GO:0030008; GO:0005783; GO:0016192,Golgi apparatus; TRAPP complex; endoplasmic reticulum; vesicle-mediated transport,PF04051;,2.00E-58,CHOYP_LOC100892925.2.2,3.00E-136,ruditapes_c7332,,,,,TPPC5_CHICK,Gallus gallus (Chicken),vesicle-mediated transport [GO:0016192] comp134724_c0_seq2,683,46.9985,0.67275304,21,106,,2.00E-120,Q15438,"Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)","Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)",GO:0005086; GO:0005737; GO:0090162; GO:0005543; GO:0005886; GO:0032012; GO:0030155; GO:0005923; GO:0016192,ARF guanyl-nucleotide exchange factor activity; cytoplasm; establishment of epithelial cell polarity; phospholipid binding; plasma membrane; regulation of ARF protein signal transduction; regulation of cell adhesion; tight junction; vesicle-mediated transport,PF00169;PF01369;,4.00E-165,CHOYP_CYH1.1.1,,,,,,,CYH1_HUMAN,Homo sapiens (Human),regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192] comp134732_c0_seq1,1427,43.2376,0.64150975,5,0,,4.00E-154,Q7T0Y4,Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164),Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164),GO:0070286; GO:0060285; GO:0035085; GO:0005856,axonemal dynein complex assembly; ciliary cell motility; cilium axoneme; cytoskeleton,PF14775;,0,CHOYP_LOC575509.2.2,,,,,,,CC164_XENLA,Xenopus laevis (African clawed frog),axonemal dynein complex assembly [GO:0070286]; bacterial-type flagellum-dependent cell motility [GO:0071973]; cilium-dependent cell motility [GO:0060285] comp134732_c0_seq2,2629,42.3735,0.51236086,1381,32,,0,Q7T0Y4,Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164),Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164),GO:0070286; GO:0060285; GO:0035085; GO:0005856,axonemal dynein complex assembly; ciliary cell motility; cilium axoneme; cytoskeleton,PF14775;,1.00E-178,CHOYP_LOC575509.1.2,,,,,,,CC164_XENLA,Xenopus laevis (African clawed frog),axonemal dynein complex assembly [GO:0070286]; bacterial-type flagellum-dependent cell motility [GO:0071973]; cilium-dependent cell motility [GO:0060285] comp134733_c0_seq1,1716,35.373,0.54723615,122,137,,1.00E-08,P74148,Universal stress protein Sll1388 (USP Sll1388),Universal stress protein Sll1388 (USP Sll1388),GO:0006950,response to stress,PF00582;,1.00E-48,CHOYP_NEMVEDRAFT_V1G236658.2.6,1.00E-16,ruditapes_c4126,,,,,Y1388_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),response to stress [GO:0006950] comp134734_c0_seq2,1079,44.1149,0.45896454,91,406,,2.00E-09,Q96FB5,Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1),Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1),GO:0016021; GO:0000179; GO:0031167,"integral to membrane; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation",PF13679;,,,,,,,,,RRNAD_HUMAN,Homo sapiens (Human), comp134734_c0_seq4,1017,41.4946,0.25380229,107,925,,8.00E-14,Q8N6Q8,Methyltransferase-like protein 25 (EC 2.1.1.-),Methyltransferase-like protein 25 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF13679;,,,,,,,,,MET25_HUMAN,Homo sapiens (Human), comp134742_c0_seq3,1723,45.0377,0.56506083,63,10,,2.00E-124,O70496,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,1.00E-137,CHOYP_CLCN7.2.3,,,,,,,CLCN7_MOUSE,Mus musculus (Mouse),response to pH [GO:0009268] comp134745_c0_seq1,1992,40.3614,1.09893589,0,0,,,,,,,,,8.00E-15,CHOYP_BRAFLDRAFT_225844.2.2,,,,,,,,, comp134745_c0_seq2,1541,43.4783,1.00307471,0,0,,5.00E-81,P54315,Inactive pancreatic lipase-related protein 1 (PL-RP1),Inactive pancreatic lipase-related protein 1 (PL-RP1),GO:0005509; GO:0005576; GO:0006629; GO:0004806,calcium ion binding; extracellular region; lipid metabolic process; triglyceride lipase activity,PF00151;PF01477;,6.00E-15,CHOYP_LIPR2.2.2,,,,,,,LIPR1_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629] comp134745_c0_seq3,1508,43.7003,0.98700182,0,0,,7.00E-76,Q64425,Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) (Fragment),Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) (Fragment),GO:0005576; GO:0016042; GO:0046872; GO:0004806,extracellular region; lipid catabolic process; metal ion binding; triglyceride lipase activity,PF00151;PF01477;,,,,,,,,,LIPP_MYOCO,Myocastor coypus (Coypu) (Nutria),lipid catabolic process [GO:0016042] comp134745_c0_seq4,1959,40.4798,1.08503681,11,8,,,,,,,,,8.00E-15,CHOYP_BRAFLDRAFT_225844.2.2,,,,,,,,, comp134749_c0_seq1,1449,37.8192,0.45340243,3613,14793,,6.00E-132,Q9PTW9,Proteasome subunit alpha type-7 (EC 3.4.25.1) (Proteasome subunit alpha 4),Proteasome subunit alpha type-7 (EC 3.4.25.1) (Proteasome subunit alpha 4),GO:0005737; GO:0005634; GO:0005839; GO:0019773; GO:0004298; GO:0006511,"cytoplasm; nucleus; proteasome core complex; proteasome core complex, alpha-subunit complex; threonine-type endopeptidase activity; ubiquitin-dependent protein catabolic process",PF00227;PF10584;,2.00E-146,CHOYP_BRAFLDRAFT_279789.3.3,0,ruditapes2_c1800,7.00E-151,BQ426386.p.cg.6,8,,PSA7_CARAU,Carassius auratus (Goldfish),ubiquitin-dependent protein catabolic process [GO:0006511] comp134751_c0_seq2,1602,45.5056,0.57451714,7,0,,5.00E-83,Q9VX91,E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin) (Ubiquitin-protein ligase E3-alpha),E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin) (Ubiquitin-protein ligase E3-alpha),GO:0030163; GO:0004842; GO:0008270,protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02617;PF10390;PF02207;,,,,,,,,,UBR1_DROME,Drosophila melanogaster (Fruit fly),transcription elongation from RNA polymerase II promoter [GO:0006368]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp134751_c0_seq4,1590,45.5346,0.57841143,1,5,,7.00E-143,Q8IWV8,E3 ubiquitin-protein ligase UBR2 (EC 6.3.2.-) (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II),E3 ubiquitin-protein ligase UBR2 (EC 6.3.2.-) (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II),GO:0071233; GO:0000785; GO:0006342; GO:0033522; GO:0070728; GO:0007141; GO:0032007; GO:0005634; GO:0005886; GO:0007283; GO:0000151; GO:0006511; GO:0004842; GO:0008270,cellular response to leucine; chromatin; chromatin silencing; histone H2A ubiquitination; leucine binding; male meiosis I; negative regulation of TOR signaling cascade; nucleus; plasma membrane; spermatogenesis; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02617;PF02207;,2.00E-65,CHOYP_UBR2.2.2,,,,,,,UBR2_HUMAN,Homo sapiens (Human),cellular response to leucine [GO:0071233]; chromatin silencing [GO:0006342]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; negative regulation of TOR signaling [GO:0032007]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp134752_c0_seq1,2272,32.5264,0.51712937,3371,10149,,7.00E-28,Q03958,Prefoldin subunit 6 (Protein Ke2),Prefoldin subunit 6 (Protein Ke2),GO:0051131; GO:0005634; GO:0016272; GO:0006457,chaperone-mediated protein complex assembly; nucleus; prefoldin complex; protein folding,PF01920;,3.00E-40,CHOYP_NEMVEDRAFT_V1G248362.1.1,,,,,,,PFD6_MOUSE,Mus musculus (Mouse),chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457] comp134753_c0_seq2,1231,38.9927,0.48138708,21,177,,3.00E-55,Q2KIS2,"39S ribosomal protein L44, mitochondrial (L44mt) (MRP-L44) (EC 3.1.26.-)","39S ribosomal protein L44, mitochondrial (L44mt) (MRP-L44) (EC 3.1.26.-)",GO:0003723; GO:0006396; GO:0005739; GO:0090305; GO:0004525; GO:0005840,RNA binding; RNA processing; mitochondrion; nucleic acid phosphodiester bond hydrolysis; ribonuclease III activity; ribosome,,7.00E-13,CHOYP_LOC582626.1.1,5.00E-19,ruditapes_c31848,,,,,RM44_BOVIN,Bos taurus (Bovine),"mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" comp134756_c0_seq2,1228,38.2736,0.22451194,0,10,,,,,,,,,,,1.00E-14,ruditapes_c29214,,,,,,, comp134757_c0_seq1,1837,45.1279,0.49019158,20,29,,0,P35520,Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase),Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase),GO:0019448; GO:0006565; GO:0030554; GO:0001974; GO:0060351; GO:0034641; GO:0071456; GO:0021587; GO:0004122; GO:0006535; GO:0019343; GO:0005829; GO:0001958; GO:0020037; GO:0043418; GO:0070814; GO:0060135; GO:0046872; GO:0072341; GO:0043066; GO:0005730; GO:0042803; GO:0030170; GO:0043506; GO:0050880; GO:0030823; GO:0051593; GO:0006801; GO:0019346,L-cysteine catabolic process; L-serine catabolic process; adenyl nucleotide binding; blood vessel remodeling; cartilage development involved in endochondral bone morphogenesis; cellular nitrogen compound metabolic process; cellular response to hypoxia; cerebellum morphogenesis; cystathionine beta-synthase activity; cysteine biosynthetic process from serine; cysteine biosynthetic process via cystathionine; cytosol; endochondral ossification; heme binding; homocysteine catabolic process; hydrogen sulfide biosynthetic process; maternal process involved in female pregnancy; metal ion binding; modified amino acid binding; negative regulation of apoptotic process; nucleolus; protein homodimerization activity; pyridoxal phosphate binding; regulation of JUN kinase activity; regulation of blood vessel size; regulation of cGMP metabolic process; response to folic acid; superoxide metabolic process; transsulfuration,PF00571;PF00291;,0,CHOYP_CBS.2.2,,,,,,,CBS_HUMAN,Homo sapiens (Human),cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process from serine [GO:0006535]; cysteine biosynthetic process via cystathionine [GO:0019343]; DNA protection [GO:0042262]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; hydrogen sulfide biosynthetic process [GO:0070814]; L-cysteine catabolic process [GO:0019448]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; transsulfuration [GO:0019346] comp134757_c0_seq2,1660,44.6988,0.44610247,1,0,,3.00E-113,P32582,Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) (Sulfur transfer protein 4),Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) (Sulfur transfer protein 4),GO:0030554; GO:0004122; GO:0006535; GO:0019343; GO:0005737; GO:0070814; GO:0019346; GO:0007089,adenyl nucleotide binding; cystathionine beta-synthase activity; cysteine biosynthetic process from serine; cysteine biosynthetic process via cystathionine; cytoplasm; hydrogen sulfide biosynthetic process; transsulfuration; traversing start control point of mitotic cell cycle,PF00571;PF00291;,,,,,,,,,CBS_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cysteine biosynthetic process from serine [GO:0006535]; cysteine biosynthetic process via cystathionine [GO:0019343]; hydrogen sulfide biosynthetic process [GO:0070814]; transsulfuration [GO:0019346]; traversing start control point of mitotic cell cycle [GO:0007089] comp134760_c0_seq1,222,50,0.4424693,11,0,,,,,,,,,2.00E-24,CHOYP_SMP_096370.2.2,,,,,,,,, comp134760_c0_seq3,1562,43.662,0.61288802,3,0,,5.00E-07,Q505D9,Tripartite motif-containing protein 67,Tripartite motif-containing protein 67,GO:0005737; GO:0005856; GO:0046580; GO:0010976; GO:2000060; GO:0008270,cytoplasm; cytoskeleton; negative regulation of Ras protein signal transduction; positive regulation of neuron projection development; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; zinc ion binding,PF00041;PF00622;PF00643;PF00097;,,,,,,,,,TRI67_MOUSE,Mus musculus (Mouse),negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060] comp134760_c0_seq4,3007,45.4273,0.56980372,129,105,,0,Q8BX90,Fibronectin type-III domain-containing protein 3A,Fibronectin type-III domain-containing protein 3A,GO:0000139; GO:0060009; GO:0001669; GO:0016337; GO:0005829; GO:0009566; GO:0016021; GO:0007286; GO:0012506,Golgi membrane; Sertoli cell development; acrosomal vesicle; cell-cell adhesion; cytosol; fertilization; integral to membrane; spermatid development; vesicle membrane,PF00041;,4.00E-166,CHOYP_PHUM_PHUM137710.1.1,,,,,,,FND3A_MOUSE,Mus musculus (Mouse),fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; single organismal cell-cell adhesion [GO:0016337]; spermatid development [GO:0007286] comp134766_c0_seq1,1722,43.3798,0.35080944,26,31,,0,Q8AVL0,CWF19-like protein 1,CWF19-like protein 1,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF04677;PF04676;,2.00E-48,CHOYP_C19L1.1.1,,,,,,,C19L1_XENLA,Xenopus laevis (African clawed frog), comp134766_c0_seq2,1287,43.8228,0.33024391,2,0,,4.00E-139,Q8AVL0,CWF19-like protein 1,CWF19-like protein 1,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF04677;PF04676;,,,,,,,,,C19L1_XENLA,Xenopus laevis (African clawed frog), comp134769_c2_seq1,717,38.4937,0.9475314,20,178,,9.00E-11,Q9QZ85,Interferon-inducible GTPase 1 (EC 3.6.5.-),Interferon-inducible GTPase 1 (EC 3.6.5.-),GO:0019003; GO:0005525; GO:0003924; GO:0032580; GO:0035458; GO:0019221; GO:0050829; GO:0042832; GO:0005789; GO:0042802; GO:0045087; GO:0031965; GO:0010506; GO:0020005,GDP binding; GTP binding; GTPase activity; Golgi cisterna membrane; cellular response to interferon-beta; cytokine-mediated signaling pathway; defense response to Gram-negative bacterium; defense response to protozoan; endoplasmic reticulum membrane; identical protein binding; innate immune response; nuclear membrane; regulation of autophagy; symbiont-containing vacuole membrane,PF05049;,,,,,,,,,IIGP1_MOUSE,Mus musculus (Mouse),cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506] comp134770_c1_seq1,1233,42.7413,0.92661433,26,187,,2.00E-13,Q868T3,Cardioacceleratory peptide receptor,Cardioacceleratory peptide receptor (Crustacean cardioactive peptide receptor),GO:0018990; GO:0005887; GO:0008188; GO:0005000,"ecdysis, chitin-based cuticle; integral to plasma membrane; neuropeptide receptor activity; vasopressin receptor activity",PF00001;,,,,,,,,,CCAPR_DROME,Drosophila melanogaster (Fruit fly),"ecdysis, chitin-based cuticle [GO:0018990]; G-protein coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]" comp134771_c0_seq1,1054,35.1992,0.56825714,277,1799,,1.00E-46,Q6DDY9,"28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)","28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)",GO:0003723; GO:0022627; GO:0005739; GO:0003735; GO:0006412,RNA binding; cytosolic small ribosomal subunit; mitochondrion; structural constituent of ribosome; translation,PF00177;,,,,,,,,,RT07_XENLA,Xenopus laevis (African clawed frog),mitochondrial translation [GO:0032543] comp134772_c0_seq1,1429,38.5584,0.60481129,447,1470,,1.00E-111,P18421,Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain),Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,,,,,,,,,PSB1_RAT,Rattus norvegicus (Rat),proteolysis involved in cellular protein catabolic process [GO:0051603] comp134772_c0_seq2,1413,38.4996,0.61371559,644,2225,,1.00E-111,P18421,Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain),Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,1.00E-68,CHOYP_PSB1.2.2,2.00E-145,ruditapes_c5996,,,,,PSB1_RAT,Rattus norvegicus (Rat),proteolysis involved in cellular protein catabolic process [GO:0051603] comp134776_c0_seq1,2094,37.6313,0.53840083,3523,9896,,0,P46507,26S protease regulatory subunit 6B (ATPase MS73),26S protease regulatory subunit 6B (ATPase MS73),GO:0005524; GO:0005737; GO:0017111; GO:0005634; GO:0000502; GO:0030163,ATP binding; cytoplasm; nucleoside-triphosphatase activity; nucleus; proteasome complex; protein catabolic process,PF00004;,0,CHOYP_PRS6B.1.1,0,ruditapes2_c3331,,,,,PRS6B_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),protein catabolic process [GO:0030163] comp134777_c1_seq1,1167,43.8732,0.97166961,3,63,,4.00E-94,P31429,Dipeptidase 1 (EC 3.4.13.19) (43 kDa renal band 3-related protein) (Microsomal dipeptidase),Dipeptidase 1 (EC 3.4.13.19) (43 kDa renal band 3-related protein) (Microsomal dipeptidase),GO:0034235; GO:0031225; GO:0016999; GO:0045177; GO:0016324; GO:0071277; GO:0035690; GO:0071732; GO:0043027; GO:0008239; GO:0005615; GO:0050667; GO:0070573; GO:0031528; GO:0072341; GO:0043066; GO:0030336; GO:0005886; GO:0006508; GO:0008270,GPI anchor binding; anchored to membrane; antibiotic metabolic process; apical part of cell; apical plasma membrane; cellular response to calcium ion; cellular response to drug; cellular response to nitric oxide; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; dipeptidyl-peptidase activity; extracellular space; homocysteine metabolic process; metallodipeptidase activity; microvillus membrane; modified amino acid binding; negative regulation of apoptotic process; negative regulation of cell migration; plasma membrane; proteolysis; zinc ion binding,PF01244;,6.00E-58,CHOYP_LOC100876551.1.1,,,,,,,DPEP1_RABIT,Oryctolagus cuniculus (Rabbit),antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to nitric oxide [GO:0071732]; homocysteine metabolic process [GO:0050667]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154] comp134777_c1_seq2,1010,42.4752,0.89362354,2,76,,,,,,,,,,,1.00E-32,ruditapes2_c1491,,,,,,, comp134778_c2_seq1,1458,43.1413,0.59176973,6,164,,1.00E-124,Q5R3I4,Tetratricopeptide repeat protein 38 (TPR repeat protein 38),Tetratricopeptide repeat protein 38 (TPR repeat protein 38),,,,,,,,,,,,TTC38_HUMAN,Homo sapiens (Human), comp134779_c0_seq1,2389,39.1796,0.58197617,293,2252,,1.00E-109,Q9BUK6,Protein misato homolog 1,Protein misato homolog 1,GO:0005741; GO:0048311,mitochondrial outer membrane; mitochondrion distribution,PF10644;PF14881;,,,,,,,,,MSTO1_HUMAN,Homo sapiens (Human),mitochondrion distribution [GO:0048311]; mitochondrion organization [GO:0007005] comp134780_c1_seq1,1527,40.2096,0.86329561,75,436,,2.00E-107,Q8QGV2,Wee1-like protein kinase 1-B (EC 2.7.10.2) (Zygotic wee1-like protein kinase 1B) (Xe-Wee1B) (XeWee1B),Wee1-like protein kinase 1-B (EC 2.7.10.2) (Zygotic wee1-like protein kinase 1B) (Xe-Wee1B) (XeWee1B),GO:0005524; GO:0051301; GO:0000287; GO:0007067; GO:0004715; GO:0005634; GO:0018108; GO:0004674,ATP binding; cell division; magnesium ion binding; mitosis; non-membrane spanning protein tyrosine kinase activity; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity,PF00069;,2.00E-85,CHOYP_LOC100646268.1.1,,,,,,,WEE1B_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of cell cycle [GO:0045786] comp134782_c0_seq1,1428,49.3697,0.36828135,2477,6106,,7.00E-89,Q8HXM1,Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64),Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64),GO:0003723; GO:0071920; GO:0005847; GO:0006397; GO:0000166,RNA binding; cleavage body; mRNA cleavage and polyadenylation specificity factor complex; mRNA processing; nucleotide binding,PF14327;PF14304;PF00076;,6.00E-141,CHOYP_LOC100701725.1.1,,,,,,,CSTF2_BOVIN,Bos taurus (Bovine),mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789] comp134796_c0_seq1,2063,43.238,0.65465435,17,8,,0,A7MBL8,Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2),Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2),GO:0005524; GO:0007155; GO:0007049; GO:0051301; GO:0030054; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0016020; GO:0030496; GO:0005634; GO:0004697; GO:0006355; GO:0007165; GO:0006351,"ATP binding; cell adhesion; cell cycle; cell division; cell junction; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; membrane; midbody; nucleus; protein kinase C activity; regulation of transcription, DNA-dependent; signal transduction; transcription, DNA-dependent",PF02185;PF00069;PF00433;,3.00E-33,CHOYP_AKT1.2.2,,,,,,,PKN2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134796_c0_seq2,2381,43.0911,0.62745483,35,38,,,,,,,,,0,CHOYP_LOC100377872.1.1,,,,,,,,, comp134799_c0_seq1,1868,36.5632,0.37285985,217,1318,,1.00E-112,A8E7G4,Protein FAM45A (Protein FAM45),Protein FAM45A (Protein FAM45),,,,,,,,,,,,FA45A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp134803_c0_seq3,1249,37.3098,0.80879278,2,4,,1.00E-05,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp134804_c0_seq1,1509,41.882,0.45566584,137,172,,2.00E-95,Q9CWT6,Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28),Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28),GO:0005524; GO:0008026; GO:0003723; GO:0042645; GO:0005739; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA binding; mitochondrial nucleoid; mitochondrion; nucleolus,PF00270;PF00271;,,,,,,,,,DDX28_MOUSE,Mus musculus (Mouse),mitochondrial large ribosomal subunit assembly [GO:1902775]; RNA secondary structure unwinding [GO:0010501] comp134806_c0_seq1,281,45.5516,0.48621305,1,56,,2.00E-22,Q5RFF7,Tetratricopeptide repeat protein 38 (TPR repeat protein 38),Tetratricopeptide repeat protein 38 (TPR repeat protein 38),,,,,,,,,,,,TTC38_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp134806_c1_seq1,771,42.2827,0.91187046,15,298,,5.00E-25,A3KPN8,Tetratricopeptide repeat protein 38 (TPR repeat protein 38),Tetratricopeptide repeat protein 38 (TPR repeat protein 38),,,,,,,,,,,,TTC38_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp134807_c0_seq1,2525,36.6733,0.55664862,571,2478,,2.00E-128,A9UMS3,Prohibitin-2,Prohibitin-2,GO:0005743; GO:0005634; GO:0006355; GO:0006351,"mitochondrial inner membrane; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01145;,,,,,,,,,PHB2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134807_c0_seq2,2481,36.5175,0.51140118,802,2420,,1.00E-128,A9UMS3,Prohibitin-2,Prohibitin-2,GO:0005743; GO:0005634; GO:0006355; GO:0006351,"mitochondrial inner membrane; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01145;,2.00E-100,CHOYP_ISCW_ISCW021457.1.1,6.00E-72,ruditapes_c9446,,,,,PHB2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134808_c0_seq1,799,44.4305,1.2209876,3,57,,1.00E-91,Q17031,Cdc42 homolog (25 kDa GTP-binding protein),Cdc42 homolog (25 kDa GTP-binding protein),GO:0005525; GO:0005912; GO:0005622; GO:0007275; GO:0005886; GO:0007264,GTP binding; adherens junction; intracellular; multicellular organismal development; plasma membrane; small GTPase mediated signal transduction,PF00071;,1.00E-33,CHOYP_CDC42.4.11,2.00E-21,ruditapes_c30722,,,,,CDC42_ANOGA,Anopheles gambiae (African malaria mosquito),multicellular organism development [GO:0007275]; small GTPase mediated signal transduction [GO:0007264] comp134808_c0_seq2,1008,43.5516,1.15687001,11,65,,2.00E-10,P35294,Ras-related protein Rab-19,Ras-related protein Rab-19,GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,9.00E-17,CHOYP_RAC1.3.3,,,,,,,RAB19_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp134811_c1_seq2,1696,37.1462,0.63281989,42,0,,5.00E-06,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,4.00E-11,CHOYP_contig_042555,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp134815_c0_seq1,1159,38.8266,0.34702166,5,0,,4.00E-25,Q5Z754,Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23),Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23),GO:0005524; GO:0008353; GO:0004693,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein serine/threonine kinase activity,PF00069;,,,,,,,,,CDKF1_ORYSJ,Oryza sativa subsp. japonica (Rice), comp134815_c0_seq2,1276,39.4984,0.34498178,21,1,,4.00E-149,P50613,Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit),Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit),GO:0006370; GO:0005524; GO:0008094; GO:0000082; GO:0000086; GO:0008353; GO:0050681; GO:0030521; GO:0007050; GO:0051301; GO:0008283; GO:0004693; GO:0005675; GO:0005739; GO:0000718; GO:0048471; GO:0045944; GO:0050434; GO:0000079; GO:0006363; GO:0003713; GO:0006362; GO:0006368; GO:0006361; GO:0006367; GO:0006283; GO:0016032,"7-methylguanosine mRNA capping; ATP binding; DNA-dependent ATPase activity; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; RNA polymerase II carboxy-terminal domain kinase activity; androgen receptor binding; androgen receptor signaling pathway; cell cycle arrest; cell division; cell proliferation; cyclin-dependent protein serine/threonine kinase activity; holo TFIIH complex; mitochondrion; nucleotide-excision repair, DNA damage removal; perinuclear region of cytoplasm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; regulation of cyclin-dependent protein serine/threonine kinase activity; termination of RNA polymerase I transcription; transcription coactivator activity; transcription elongation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; viral process",PF00069;,6.00E-84,CHOYP_LOC100748883.1.1,,,,,,,CDK7_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; androgen receptor signaling pathway [GO:0030521]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; cell proliferation [GO:0008283]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; termination of RNA polymerase I transcription [GO:0006363]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp134818_c0_seq1,1480,41.0811,0.99487558,18,437,,8.00E-67,P48594,Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2),Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2),GO:0005737; GO:0005576; GO:0005615; GO:0006955; GO:0030162; GO:0004867,cytoplasm; extracellular region; extracellular space; immune response; regulation of proteolysis; serine-type endopeptidase inhibitor activity,PF00079;,,,,,,,,,SPB4_HUMAN,Homo sapiens (Human),negative regulation of peptidase activity [GO:0010466]; protection from natural killer cell mediated cytotoxicity [GO:0042270]; regulation of proteolysis [GO:0030162] comp134819_c0_seq1,1962,42.5586,0.70194692,2599,132,,2.00E-87,Q6PBA8,Meiosis-specific nuclear structural protein 1,Meiosis-specific nuclear structural protein 1,GO:0007126; GO:0005634,meiosis; nucleus,,0,CHOYP_BRAFLDRAFT_245349.1.1,8.00E-82,ruditapes_c10790,,,,,MNS1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),meiotic cell cycle [GO:0051321] comp134820_c0_seq1,2476,40.3473,0.47013541,26,119,,0,Q96GQ7,Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27),Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27),GO:0005524; GO:0008026; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; nucleic acid binding; nucleus,PF00270;PF00271;,0,CHOYP_VP13D.2.3,,,,,,,DDX27_HUMAN,Homo sapiens (Human),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp134820_c0_seq2,2455,40.3666,0.47359868,0,9,,2.00E-61,Q2HEB0,Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0008380; GO:0005737; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; cytoplasm; mRNA processing; nucleic acid binding; nucleus,PF00270;PF00271;,0,CHOYP_VP13D.2.3,1.00E-62,ruditapes_c25450,,,,,PRP28_CHAGB,Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp134821_c1_seq1,959,35.245,0.41933651,109,615,,4.00E-12,B0S1F7,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ_FINM2,Finegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp134828_c2_seq6,531,44.0678,0.89392485,0,0,,4.00E-09,Q8JZW5,SH2 domain-containing protein 5,SH2 domain-containing protein 5,,,,,,,,,,,,SH2D5_MOUSE,Mus musculus (Mouse), comp134828_c2_seq8,725,43.5862,0.81756912,0,0,,2.00E-20,Q6ZV89,SH2 domain-containing protein 5,SH2 domain-containing protein 5,,,,5.00E-56,CHOYP_SMP_105540.1.1,,,,,,,SH2D5_HUMAN,Homo sapiens (Human), comp134830_c0_seq1,1731,38.6482,0.38943064,472,2589,,2.00E-96,Q2T9V5,tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6),tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6),GO:0005634; GO:0006446; GO:0008033; GO:0003743,nucleus; regulation of translational initiation; tRNA processing; translation initiation factor activity,PF04189;,3.00E-44,CHOYP_TRMT6.1.1,,,,,,,TRM6_BOVIN,Bos taurus (Bovine),tRNA methylation [GO:0030488] comp134836_c0_seq2,1941,44.6162,0.50064194,206,83,,7.00E-174,Q6DTM3,Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1),Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1),GO:0070121; GO:0036038; GO:0005912; GO:0005911; GO:0034613; GO:0005814; GO:0042384; GO:0035844; GO:0001947; GO:0030902; GO:0070986; GO:0005932; GO:0001738; GO:0043066; GO:0071599; GO:0035845; GO:0030862; GO:0002092; GO:0045944; GO:0039023; GO:0039008; GO:0050795; GO:0010842; GO:0065001; GO:0007169; GO:0016192,Kupffer's vesicle development; TCTN-B9D complex; adherens junction; cell-cell junction; cellular protein localization; centriole; cilium assembly; cloaca development; heart looping; hindbrain development; left/right axis specification; microtubule basal body; morphogenesis of a polarized epithelium; negative regulation of apoptotic process; otic vesicle development; photoreceptor cell outer segment organization; positive regulation of polarized epithelial cell differentiation; positive regulation of receptor internalization; positive regulation of transcription from RNA polymerase II promoter; pronephric duct morphogenesis; pronephric nephron tubule morphogenesis; regulation of behavior; retina layer formation; specification of axis polarity; transmembrane receptor protein tyrosine kinase signaling pathway; vesicle-mediated transport,PF00018;PF00400;,8.00E-78,CHOYP_LOC100710392.2.2,,,,,,,AHI1_RAT,Rattus norvegicus (Rat),cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192] comp134836_c0_seq3,376,36.1702,0.32640924,3,0,,2.00E-17,Q8N157,Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1),Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1),GO:0070121; GO:0036038; GO:0005912; GO:0005911; GO:0034613; GO:0005814; GO:0042384; GO:0035844; GO:0001947; GO:0030902; GO:0070986; GO:0005932; GO:0001738; GO:0043066; GO:0071599; GO:0035845; GO:0030862; GO:0002092; GO:0045944; GO:0039023; GO:0039008; GO:0033365; GO:0050795; GO:0010842; GO:0065001; GO:0007169; GO:0016192,Kupffer's vesicle development; TCTN-B9D complex; adherens junction; cell-cell junction; cellular protein localization; centriole; cilium assembly; cloaca development; heart looping; hindbrain development; left/right axis specification; microtubule basal body; morphogenesis of a polarized epithelium; negative regulation of apoptotic process; otic vesicle development; photoreceptor cell outer segment organization; positive regulation of polarized epithelial cell differentiation; positive regulation of receptor internalization; positive regulation of transcription from RNA polymerase II promoter; pronephric duct morphogenesis; pronephric nephron tubule morphogenesis; protein localization to organelle; regulation of behavior; retina layer formation; specification of axis polarity; transmembrane receptor protein tyrosine kinase signaling pathway; vesicle-mediated transport,PF00018;PF00400;,,,,,,,,,AHI1_HUMAN,Homo sapiens (Human),cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192] comp134841_c0_seq1,1054,31.9734,0.41550342,42,280,,2.00E-11,Q6WRH9,Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608),Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608),GO:0030154; GO:0005576; GO:0007275; GO:0001503; GO:0042246,cell differentiation; extracellular region; multicellular organismal development; ossification; tissue regeneration,PF07679;PF13855;,,,,,,,,,IGS10_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; tissue regeneration [GO:0042246] comp134842_c0_seq2,1365,39.707,0.92777096,173,1491,,5.00E-58,Q80XN0,"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase)","D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH)",GO:0003858; GO:0060612; GO:0007420; GO:0001889; GO:0005743; GO:0005759; GO:0005543; GO:0046686; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0060416; GO:0032868; GO:0007584; GO:0042594; GO:0009636,3-hydroxybutyrate dehydrogenase activity; adipose tissue development; brain development; liver development; mitochondrial inner membrane; mitochondrial matrix; phospholipid binding; response to cadmium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to growth hormone stimulus; response to insulin stimulus; response to nutrient; response to starvation; response to toxic substance,PF00106;,,,1.00E-27,ruditapes_c11402,,,,,BDH_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; brain development [GO:0007420]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636] comp134846_c0_seq1,1645,40.304,0.41054222,679,1943,,1.00E-171,P52899,"Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)","Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)",GO:0006096; GO:0005759; GO:0005739; GO:0004739,glycolysis; mitochondrial matrix; mitochondrion; pyruvate dehydrogenase (acetyl-transferring) activity,PF00676;,3.00E-121,CHOYP_PDHA1.1.1,,,,,,,ODPA_CAEEL,Caenorhabditis elegans,acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] comp134848_c0_seq1,2157,37.4131,0.46817093,167,538,,4.00E-25,O15091,Mitochondrial ribonuclease P protein 3 (Mitochondrial RNase P protein 3),Mitochondrial ribonuclease P protein 3 (Mitochondrial RNase P protein 3),GO:0005739; GO:0008033,mitochondrion; tRNA processing,PF16953;,,,,,,,,,MRRP3_HUMAN,Homo sapiens (Human),mitochondrial tRNA processing [GO:0090646] comp134852_c0_seq1,1083,39.3352,0.74543098,31,159,,5.00E-54,Q5WRN3,N(6)-adenine-specific DNA methyltransferase 2 homolog (EC 2.1.1.-),Protein-lysine N-methyltransferase M142.8 (EC 2.1.1.-),GO:0008168; GO:0003676,methyltransferase activity; nucleic acid binding,PF10237;,,,,,,,,,N6MT2_CAEEL,Caenorhabditis elegans, comp134852_c0_seq2,839,38.975,0.63105792,0,58,,5.00E-80,Q6GN98,N(6)-adenine-specific DNA methyltransferase 2 (EC 2.1.1.-),Protein-lysine N-methyltransferase n6amt2 (EC 2.1.1.-) (N(6)-adenine-specific DNA methyltransferase 2),GO:0008168; GO:0003676,methyltransferase activity; nucleic acid binding,PF10237;,,,,,,,,,N6MT2_XENLA,Xenopus laevis (African clawed frog), comp134853_c0_seq1,1113,38.6343,1.01534337,35,195,,7.00E-20,Q86GC8,Acetylcholinesterase (AChE) (EC 3.1.1.7),Acetylcholinesterase (AChE) (EC 3.1.1.7),GO:0003990; GO:0004091; GO:0030054; GO:0005576; GO:0042135; GO:0005886; GO:0045202,acetylcholinesterase activity; carboxylesterase activity; cell junction; extracellular region; neurotransmitter catabolic process; plasma membrane; synapse,PF00135;,,,,,,,,,ACES_CULPI,Culex pipiens (House mosquito),neurotransmitter catabolic process [GO:0042135] comp134854_c1_seq1,1844,45.1193,0.49219702,111,94,,2.00E-77,Q9D3A8,Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein),Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein),,,PF00640;,2.00E-60,CHOYP_CAPON.1.1,,,,,,,CAPON_MOUSE,Mus musculus (Mouse), comp134860_c0_seq1,1276,38.2445,1.13247904,0,642,,9.00E-07,Q9JHG0,Cerebellin-3,Cerebellin-3,GO:0005794; GO:0030054; GO:0005783; GO:0005615; GO:0045202,Golgi apparatus; cell junction; endoplasmic reticulum; extracellular space; synapse,PF00386;,,,,,,,,,CBLN3_MOUSE,Mus musculus (Mouse), comp134863_c0_seq1,933,45.9807,0.57471937,26,126,,1.00E-66,O94761,"ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)","ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)",GO:0005524; GO:0043140; GO:0006310; GO:0006281; GO:0006260; GO:0000733; GO:0000405; GO:0005737; GO:0007275; GO:0005634; GO:0008270,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA recombination; DNA repair; DNA replication; DNA strand renaturation; bubble DNA binding; cytoplasm; multicellular organismal development; nucleus; zinc ion binding,PF00270;PF11719;PF00271;,3.00E-41,CHOYP_LOC567383.1.1,,,,,,,RECQ4_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; multicellular organism development [GO:0007275] comp134863_c1_seq1,1611,35.8783,0.64063033,74,550,,8.00E-07,Q0WVW7,ATP-dependent DNA helicase Q-like 5 (EC 3.6.4.12) (RecQ-like protein 5) (AtRecQ5) (AtRecQl5),ATP-dependent DNA helicase Q-like 5 (EC 3.6.4.12) (RecQ-like protein 5) (AtRecQ5) (AtRecQl5),GO:0005524; GO:0008026; GO:0006310; GO:0042631; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; DNA recombination; cellular response to water deprivation; nucleic acid binding; nucleus,PF00270;PF00271;,,,,,,,,,RQL5_ARATH,Arabidopsis thaliana (Mouse-ear cress),base-excision repair [GO:0006284]; cellular response to water deprivation [GO:0042631]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302] comp134870_c0_seq1,912,50.4386,0.76518187,0,0,,1.00E-32,Q5R4F5,Muscleblind-like protein 2,Muscleblind-like protein 2,GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0046872; GO:0005634; GO:0043484; GO:0000381,"RNA binding; RNA splicing; cytoplasm; mRNA processing; metal ion binding; nucleus; regulation of RNA splicing; regulation of alternative mRNA splicing, via spliceosome",PF00642;,1.00E-46,CHOYP_DSEC_GM21767.1.1,,,,,,,MBNL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] comp134870_c0_seq10,1252,47.2045,0.6639256,0,0,,2.00E-41,O16011,Protein muscleblind (Protein mindmelt),Protein muscleblind (Protein mindmelt),GO:0003677; GO:0006915; GO:0009790; GO:0007476; GO:0046872; GO:0046716; GO:0007517; GO:0005634; GO:0048471; GO:0007422; GO:0000381; GO:0045924; GO:0042052; GO:0007525; GO:0007601,"DNA binding; apoptotic process; embryo development; imaginal disc-derived wing morphogenesis; metal ion binding; muscle cell cellular homeostasis; muscle organ development; nucleus; perinuclear region of cytoplasm; peripheral nervous system development; regulation of alternative mRNA splicing, via spliceosome; regulation of female receptivity; rhabdomere development; somatic muscle development; visual perception",,,,1.00E-76,ruditapes2_c1814,,,,,MBL_DROME,Drosophila melanogaster (Fruit fly),"apoptotic process [GO:0006915]; compound eye photoreceptor cell differentiation [GO:0001751]; embryo development [GO:0009790]; eye development [GO:0001654]; imaginal disc-derived wing morphogenesis [GO:0007476]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; peripheral nervous system development [GO:0007422]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of female receptivity [GO:0045924]; regulation of gene expression [GO:0010468]; response to stimulus [GO:0050896]; rhabdomere development [GO:0042052]; somatic muscle development [GO:0007525]; visual perception [GO:0007601]" comp134870_c0_seq2,1363,47.5422,0.69128709,0,0,,4.00E-14,Q0JD07,Zinc finger CCCH domain-containing protein 28 (OsC3H28),Zinc finger CCCH domain-containing protein 28 (OsC3H28),GO:0003677; GO:0046872,DNA binding; metal ion binding,,,,,,,,,,C3H28_ORYSJ,Oryza sativa subsp. japonica (Rice), comp134870_c0_seq3,1318,47.3445,0.68029004,0,0,,,,,,,,,8.00E-19,CHOYP_LOC725564.1.1,,,,,,,,, comp134870_c0_seq5,1297,47.4171,0.67625771,0,0,,,,,,,,,2.00E-46,CHOYP_DYAK_GE11656.2.2,,,,,,,,, comp134870_c0_seq6,831,50.1805,0.75299469,0,0,,5.00E-37,Q6Q2B2,Muscleblind-like protein 2a (Tmbnl2a),Muscleblind-like protein 2a (Tmbnl2a),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0046872; GO:0005634,RNA binding; RNA splicing; cytoplasm; mRNA processing; metal ion binding; nucleus,PF00642;,1.00E-46,CHOYP_DSEC_GM21767.1.1,,,,,,,MBN2A_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp134870_c0_seq7,876,50.3425,0.76355821,0,0,,3.00E-42,O16011,Protein muscleblind (Protein mindmelt),Protein muscleblind (Protein mindmelt),GO:0003677; GO:0006915; GO:0009790; GO:0007476; GO:0046872; GO:0046716; GO:0007517; GO:0005634; GO:0048471; GO:0007422; GO:0000381; GO:0045924; GO:0042052; GO:0007525; GO:0007601,"DNA binding; apoptotic process; embryo development; imaginal disc-derived wing morphogenesis; metal ion binding; muscle cell cellular homeostasis; muscle organ development; nucleus; perinuclear region of cytoplasm; peripheral nervous system development; regulation of alternative mRNA splicing, via spliceosome; regulation of female receptivity; rhabdomere development; somatic muscle development; visual perception",,,,,,,,,,MBL_DROME,Drosophila melanogaster (Fruit fly),"apoptotic process [GO:0006915]; compound eye photoreceptor cell differentiation [GO:0001751]; embryo development [GO:0009790]; eye development [GO:0001654]; imaginal disc-derived wing morphogenesis [GO:0007476]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; peripheral nervous system development [GO:0007422]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of female receptivity [GO:0045924]; regulation of gene expression [GO:0010468]; response to stimulus [GO:0050896]; rhabdomere development [GO:0042052]; somatic muscle development [GO:0007525]; visual perception [GO:0007601]" comp134870_c0_seq8,482,43.9834,0.64503483,7,0,,,,,,,,,2.00E-27,CHOYP_LOC725564.1.1,,,,,,,,, comp134870_c0_seq9,1333,47.5619,0.68061263,0,0,,7.00E-40,Q94250,Muscleblind-like protein (CeMBL),Muscleblind-like protein (CeMBL),GO:0003723; GO:0046872; GO:0005634,RNA binding; metal ion binding; nucleus,,2.00E-46,CHOYP_DYAK_GE11656.2.2,,,,,,,MBL_CAEEL,Caenorhabditis elegans, comp134871_c2_seq1,900,46.7778,0.34689992,14,44,,7.00E-64,Q91X58,AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein),AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein),GO:0005783; GO:0008270,endoplasmic reticulum; zinc ion binding,PF01428;,,,,,,,,,ZFN2B_MOUSE,Mus musculus (Mouse),"SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]" comp134871_c2_seq2,898,44.2094,0.41207079,3,4,,9.00E-28,Q0D5B9,Zinc finger AN1 and C2H2 domain-containing stress-associated protein 16 (OsSAP16),Zinc finger AN1 and C2H2 domain-containing stress-associated protein 16 (OsSAP16),GO:0006950; GO:0008270,response to stress; zinc ion binding,PF01428;,,,,,,,,,SAP16_ORYSJ,Oryza sativa subsp. japonica (Rice), comp134871_c2_seq3,631,45.4834,0.46064256,0,0,,1.00E-55,Q9JII7,AN1-type zinc finger protein 2A (Arsenite-inducible RNA-associated protein),AN1-type zinc finger protein 2A (Arsenite-inducible RNA-associated protein),GO:0005737; GO:0005634; GO:0008270,cytoplasm; nucleus; zinc ion binding,PF01428;,8.00E-47,CHOYP_LOC588827.1.1,,,,,,,ZFN2A_MOUSE,Mus musculus (Mouse),cellular response to arsenic-containing substance [GO:0071243]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436] comp134875_c0_seq5,786,39.5674,0.61871169,0,0,,6.00E-69,Q6GR34,Uncharacterized protein C16orf52 homolog A,Uncharacterized protein C16orf52 homolog A,,,,,,,,,,,,CP52A_XENLA,Xenopus laevis (African clawed frog), comp134875_c0_seq6,764,39.267,0.57823228,0,0,,3.00E-32,Q8NHV5,Uncharacterized protein C16orf52,Uncharacterized protein C16orf52,,,,,,,,,,,,CP052_HUMAN,Homo sapiens (Human), comp134876_c0_seq1,1371,45.3683,0.4686959,0,11,,2.00E-52,Q54271,Phosphonopyruvate decarboxylase (EC 4.1.1.82),Phosphonopyruvate decarboxylase (EC 4.1.1.82),GO:0017000; GO:0032923; GO:0033980; GO:0030976,antibiotic biosynthetic process; organic phosphonate biosynthetic process; phosphonopyruvate decarboxylase activity; thiamine pyrophosphate binding,PF02775;PF02776;,,,,,,,,,PPD_STRHY,Streptomyces hygroscopicus,antibiotic biosynthetic process [GO:0017000]; organic phosphonate biosynthetic process [GO:0032923] comp134876_c0_seq2,1490,45.0336,0.49050436,14,81,,,,,,,,,1.00E-106,CHOYP_NEMVEDRAFT_V1G168076.2.2,,,,,,,,, comp134879_c0_seq1,799,41.1765,0.54229203,15,111,,2.00E-09,Q91X34,Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),GO:0016410; GO:0006637; GO:0006699; GO:0002152; GO:0008206; GO:0004091; GO:0005829; GO:0006631; GO:0047963; GO:0006544; GO:0001889; GO:0052815; GO:0031100; GO:0016290; GO:0005777; GO:0019530; GO:0052817,N-acyltransferase activity; acyl-CoA metabolic process; bile acid biosynthetic process; bile acid conjugation; bile acid metabolic process; carboxylesterase activity; cytosol; fatty acid metabolic process; glycine N-choloyltransferase activity; glycine metabolic process; liver development; medium-chain acyl-CoA hydrolase activity; organ regeneration; palmitoyl-CoA hydrolase activity; peroxisome; taurine metabolic process; very long chain acyl-CoA hydrolase activity,PF08840;PF04775;,,,,,,,,,BAAT_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530] comp134879_c0_seq2,499,43.487,0.77319898,3,78,,1.00E-10,A2AKK5,Acyl-coenzyme A amino acid N-acyltransferase 1 (EC 2.3.1.-),Acyl-coenzyme A amino acid N-acyltransferase 1 (EC 2.3.1.-),GO:0016410; GO:0006637; GO:0006631; GO:0005777; GO:0016790,N-acyltransferase activity; acyl-CoA metabolic process; fatty acid metabolic process; peroxisome; thiolester hydrolase activity,PF08840;PF04775;,,,,,,,,,ACNT1_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631] comp134880_c0_seq1,3425,40,0.45339132,84,253,,2.00E-38,Q3ULM6,SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1),SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1),GO:0015030; GO:0030576; GO:0032183; GO:0070140; GO:0008283; GO:0016926; GO:0004221; GO:0006511,Cajal body; Cajal body organization; SUMO binding; SUMO-specific isopeptidase activity; cell proliferation; protein desumoylation; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF15509;PF15499;,,,,,,,,,USPL1_MOUSE,Mus musculus (Mouse),Cajal body organization [GO:0030576]; cell proliferation [GO:0008283]; protein desumoylation [GO:0016926] comp134881_c0_seq1,1376,43.8953,0.39991978,90,55,,2.00E-24,A2RTY3,Uncharacterized protein C17orf66,Protein HEATR9 (HEAT repeat-containing protein 9),,,,4.00E-124,CHOYP_LOC753178.1.2,,,,,,,CQ066_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244] comp134890_c0_seq2,1490,37.9866,1.14317548,5,75,,,,,,,,,3.00E-24,CHOYP_SMP_051990.2.7,,,,,,,,, comp134891_c0_seq1,877,40.821,0.41356625,131,254,,1.00E-32,Q8N782,Zinc finger protein 525,Zinc finger protein 525,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN525_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134895_c0_seq1,1762,37.0602,0.41579418,4355,104,,,,,,,,,7.00E-91,CHOYP_BRAFLDRAFT_125862.1.1,,,,,,,,, comp134897_c0_seq1,1807,39.4023,0.53161274,0,23,,3.00E-43,Q9GZS1,DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53),DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53),GO:0003677; GO:0003899; GO:0030054; GO:0005737; GO:0005730; GO:0009303,DNA binding; DNA-directed RNA polymerase activity; cell junction; cytoplasm; nucleolus; rRNA transcription,PF06870;,,,,,,,,,RPA49_HUMAN,Homo sapiens (Human),"positive regulation of gene expression, epigenetic [GO:0045815]; RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript [GO:0001189]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp134898_c0_seq1,2118,36.5439,0.51131097,9320,47434,,7.00E-43,P19178,Histone H2A,Histone H2A,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;PF16211;,3.00E-96,CHOYP_CPIPJ_CPIJ012408.1.1,1.00E-87,ruditapes_c1797,,,,,H2A_PLADU,Platynereis dumerilii (Dumeril's clam worm), comp134903_c0_seq1,1253,37.6696,0.52372425,260,2752,,8.00E-74,Q9JHB5,Translin-associated protein X (Translin-associated factor X),Translin-associated protein X (Translin-associated factor X),GO:0005794; GO:0030154; GO:0046872; GO:0007275; GO:0005634; GO:0048471; GO:0032403; GO:0043565; GO:0007283,Golgi apparatus; cell differentiation; metal ion binding; multicellular organismal development; nucleus; perinuclear region of cytoplasm; protein complex binding; sequence-specific DNA binding; spermatogenesis,PF01997;,,,,,,,,,TSNAX_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp134906_c0_seq2,1502,44.9401,0.60993022,5,2,,9.00E-31,P23508,Colorectal mutant cancer protein (Protein MCC),Colorectal mutant cancer protein (Protein MCC),GO:0016055; GO:0005737; GO:0090090; GO:0010633; GO:0050680; GO:0005634; GO:0005886; GO:0004872; GO:0007165,Wnt receptor signaling pathway; cytoplasm; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of epithelial cell migration; negative regulation of epithelial cell proliferation; nucleus; plasma membrane; receptor activity; signal transduction,PF10506;,5.00E-22,CHOYP_contig_039932,,,,,,,CRCM_HUMAN,Homo sapiens (Human),establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] comp134909_c1_seq3,1756,43.508,0.50570523,0,0,,3.00E-158,O15084,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK),GO:0005654,nucleoplasm,PF00023;PF12796;,,,,,,,,,ANR28_HUMAN,Homo sapiens (Human),COPII vesicle coating [GO:0048208] comp134909_c1_seq4,1649,45.2395,0.45129683,0,0,,2.00E-158,O15084,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK),GO:0005654,nucleoplasm,PF00023;PF12796;,3.00E-102,CHOYP_LOC100370913.1.1,,,,,,,ANR28_HUMAN,Homo sapiens (Human),COPII vesicle coating [GO:0048208] comp134910_c1_seq1,984,41.565,0.73207939,2527,13835,,4.00E-30,P32348,Tubulin gamma chain (Gamma-tubulin),Tubulin gamma chain (Gamma-tubulin),GO:0005525; GO:0003924; GO:0031122; GO:0000930; GO:0005874; GO:0007020; GO:0051258; GO:0005816,GTP binding; GTPase activity; cytoplasmic microtubule organization; gamma-tubulin complex; microtubule; microtubule nucleation; protein polymerization; spindle pole body,PF00091;PF03953;,0,CHOYP_TBB4B.2.7,0,ruditapes_c2743,,,,,TBG_USTVI,Microbotryum violaceum (Anther smut fungus) (Ustilago violacea),cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] comp134910_c1_seq2,988,41.8016,0.71993217,0,5484,female,3.00E-135,P20802,Tubulin beta chain (Beta-tubulin),Tubulin beta chain (Beta-tubulin),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC373275.7.7,0,ruditapes2_c4168,,,,,TBB_ACHKL,Achlya klebsiana,microtubule-based process [GO:0007017] comp134910_c1_seq4,650,42,1.19256748,1275,9898,,,,,,,,,5.00E-138,CHOYP_LOC100367715.1.1,9.00E-158,ruditapes_lrc35676,,,,,,, comp134910_c1_seq5,908,42.6211,0.77713159,491,3236,,1.00E-157,P18700,Tubulin beta chain (Beta-tubulin) (Fragment),Tubulin beta chain (Beta-tubulin) (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC373275.6.7,0,ruditapes2_lrc3255,,,,,TBB_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),microtubule-based process [GO:0007017] comp134910_c1_seq6,732,41.1202,1.10128354,31,18563,female>male,,,,,,,,,,1.00E-100,ruditapes_lrc27733,,,,,,, comp134910_c1_seq7,727,40.9904,1.11510775,1189,9649,,,,,,,,,1.00E-82,CHOYP_LOC100378826.1.1,6.00E-41,ruditapes_lrc16569,,,,,,, comp134911_c0_seq1,1055,39.8104,0.40156899,19,29,,2.00E-09,A7YW45,Protein arginine N-methyltransferase 5 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT5) (EC 2.1.1.125) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog),Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (Histone-arginine N-methyltransferase PRMT5) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog),GO:0005737; GO:0042118; GO:0034969; GO:0008469; GO:0005634; GO:0035243; GO:0006355; GO:0000387; GO:0006351,"cytoplasm; endothelial cell activation; histone arginine methylation; histone-arginine N-methyltransferase activity; nucleus; protein-arginine omega-N symmetric methyltransferase activity; regulation of transcription, DNA-dependent; spliceosomal snRNP assembly; transcription, DNA-dependent",PF05185;,,,,,,,,,ANM5_BOVIN,Bos taurus (Bovine),"circadian regulation of gene expression [GO:0032922]; DNA-templated transcription, termination [GO:0006353]; endothelial cell activation [GO:0042118]; Golgi ribbon formation [GO:0090161]; histone H4-R3 methylation [GO:0043985]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]" comp134911_c0_seq2,1286,40.3577,0.35869587,5,79,,9.00E-125,P55345,Protein arginine N-methyltransferase 2 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT2) (EC 2.1.1.125),Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2),GO:0005829; GO:0048588; GO:0030331; GO:0097194; GO:0008469; GO:2000134; GO:0032088; GO:0045892; GO:0005634; GO:0045893; GO:0060765; GO:0004871; GO:0003713,"cytosol; developmental cell growth; estrogen receptor binding; execution phase of apoptosis; histone-arginine N-methyltransferase activity; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription, DNA-dependent; regulation of androgen receptor signaling pathway; signal transducer activity; transcription coactivator activity",PF05185;PF14604;,,,,,,,,,ANM2_HUMAN,Homo sapiens (Human),"developmental cell growth [GO:0048588]; histone methylation [GO:0016571]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; protein methylation [GO:0006479]; regulation of androgen receptor signaling pathway [GO:0060765]; signal transduction [GO:0007165]" comp134912_c0_seq1,1089,38.7511,0.46543549,65,65,,6.00E-74,Q16943,Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33),Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33),GO:0030054; GO:0016021; GO:0043005; GO:0005198; GO:0045202,cell junction; integral to membrane; neuron projection; structural molecule activity; synapse,PF00635;,,,,,,,,,VP33_APLCA,Aplysia californica (California sea hare),protein localization to endoplasmic reticulum [GO:0070972] comp134912_c0_seq2,619,39.4184,0.29207964,2,0,,3.00E-66,Q16943,Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33),Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33),GO:0030054; GO:0016021; GO:0043005; GO:0005198; GO:0045202,cell junction; integral to membrane; neuron projection; structural molecule activity; synapse,PF00635;,1.00E-63,CHOYP_VP33.1.2,,,,,,,VP33_APLCA,Aplysia californica (California sea hare),protein localization to endoplasmic reticulum [GO:0070972] comp134922_c0_seq1,1468,41.0082,0.7459161,260,1401,,2.00E-48,A4FUZ6,Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-),Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-),GO:0016491; GO:0005777; GO:0032934,oxidoreductase activity; peroxisome; sterol binding,PF00106;PF02036;,,,,,,,,,HSDL2_BOVIN,Bos taurus (Bovine), comp134926_c0_seq1,1571,39.529,0.38288695,401,1600,,5.00E-168,Q8BGV0,"Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)","Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)",GO:0005524; GO:0004816; GO:0006421; GO:0005759; GO:0005739; GO:0003676,ATP binding; asparagine-tRNA ligase activity; asparaginyl-tRNA aminoacylation; mitochondrial matrix; mitochondrion; nucleic acid binding,PF00152;PF01336;,,,,,,,,,SYNM_MOUSE,Mus musculus (Mouse),asparaginyl-tRNA aminoacylation [GO:0006421] comp134930_c0_seq1,568,38.9085,0.43288384,0,8,,3.00E-32,Q9D342,Transmembrane protein 170A,Transmembrane protein 170A,GO:0016021,integral to membrane,PF10190;,1.00E-11,CHOYP_LOC100647038.3.4,,,,,,,T170A_MOUSE,Mus musculus (Mouse),endoplasmic reticulum tubular network organization [GO:0071786]; nuclear envelope organization [GO:0006998]; nuclear pore complex assembly [GO:0051292] comp134936_c0_seq1,1349,44.1067,0.90659766,3,735,female>male,,,,,,,,1.00E-28,CHOYP_LOC100118354.4.4,,,,,,,,, comp134938_c0_seq1,1225,37.3061,0.40382109,73,892,,3.00E-76,Q5E9K3,Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase),Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase),GO:0010181; GO:0042823; GO:0004733; GO:0008615,FMN binding; pyridoxal phosphate biosynthetic process; pyridoxamine-phosphate oxidase activity; pyridoxine biosynthetic process,PF10590;PF01243;,3.00E-43,CHOYP_LOC100701105.1.1,,,,,,,PNPO_BOVIN,Bos taurus (Bovine),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; xenophagy [GO:0098792] comp134938_c1_seq1,987,45.1874,0.88357814,70,181,,1.00E-119,C1C4R8,3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase),3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase),GO:0003858; GO:0005737; GO:0042168; GO:0055072; GO:0016628; GO:0019290,"3-hydroxybutyrate dehydrogenase activity; cytoplasm; heme metabolic process; iron ion homeostasis; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; siderophore biosynthetic process",,,,,,,,,,BDH2_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; siderophore biosynthetic process [GO:0019290] comp134938_c1_seq2,786,44.5293,0.93197519,43,139,,4.00E-103,C1C4R8,3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase),3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase),GO:0003858; GO:0005737; GO:0042168; GO:0055072; GO:0016628; GO:0019290,"3-hydroxybutyrate dehydrogenase activity; cytoplasm; heme metabolic process; iron ion homeostasis; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; siderophore biosynthetic process",,3.00E-54,CHOYP_BDH2.1.2,,,,,,,BDH2_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; siderophore biosynthetic process [GO:0019290] comp134941_c0_seq1,1276,39.3417,0.53187057,31,334,,6.00E-20,Q8R092,Uncharacterized protein C1orf43 homolog,Uncharacterized protein C1orf43 homolog,GO:0050662; GO:0016021; GO:0016616,"coenzyme binding; integral to membrane; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF07406;,,,,,,,,,CA043_MOUSE,Mus musculus (Mouse), comp134941_c0_seq2,661,40.5446,0.59041384,0,6,,2.00E-20,Q5RF08,Uncharacterized protein C1orf43 homolog,Uncharacterized protein C1orf43 homolog,GO:0016021,integral to membrane,PF07406;,,,,,,,,,CA043_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp134945_c0_seq1,2067,39.0421,0.30501107,382,1398,,1.00E-95,D3ZV31,Zinc finger CCHC domain-containing protein 4,Zinc finger CCHC domain-containing protein 4,GO:0008168; GO:0003676; GO:0008270,methyltransferase activity; nucleic acid binding; zinc ion binding,PF10237;PF06839;,,,,,,,,,ZCHC4_RAT,Rattus norvegicus (Rat), comp134948_c0_seq1,1051,37.6784,1.07470408,35,413,,2.00E-26,Q09927,L-azetidine-2-carboxylic acid acetyltransferase (EC 2.3.1.-),L-azetidine-2-carboxylic acid acetyltransferase (EC 2.3.1.-),GO:0006526; GO:0046941; GO:0034599; GO:0005829; GO:0005634; GO:0006562,arginine biosynthetic process; azetidine-2-carboxylic acid acetyltransferase activity; cellular response to oxidative stress; cytosol; nucleus; proline catabolic process,PF00583;,,,2.00E-24,ruditapes_c23386,,,,,AZET_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),arginine biosynthetic process [GO:0006526]; proline catabolic process [GO:0006562] comp134949_c0_seq1,726,39.5317,0.57244203,33,135,,2.00E-98,O43447,Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP),Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP),GO:0071001; GO:0046540; GO:0016018; GO:0005737; GO:0000398; GO:0016607; GO:0003755; GO:0045070; GO:0006461; GO:0006457; GO:0043021; GO:0005681,"U4/U6 snRNP; U4/U6 x U5 tri-snRNP complex; cyclosporin A binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; peptidyl-prolyl cis-trans isomerase activity; positive regulation of viral genome replication; protein complex assembly; protein folding; ribonucleoprotein complex binding; spliceosomal complex",PF00160;,8.00E-92,CHOYP_RS9.11.13,1.00E-11,ruditapes2_c789,,,,,PPIH_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]" comp134951_c0_seq1,1682,37.5743,0.4948446,15846,73819,,2.00E-91,P30151,Elongation factor 1-beta (EF-1-beta) (p30),Elongation factor 1-beta (EF-1-beta) (p30),GO:0005853; GO:0003746,eukaryotic translation elongation factor 1 complex; translation elongation factor activity,PF10587;PF00736;,1.00E-31,CHOYP_EF1B.4.7,6.00E-70,ruditapes2_c1190,,,,,EF1B_XENLA,Xenopus laevis (African clawed frog), comp134953_c0_seq1,460,40.4348,0.58658461,33,65,,,,,,,,,7.00E-14,CHOYP_LOC100367769.1.2,,,,,,,,, comp134954_c0_seq1,2596,40.3698,0.47353361,0,0,,0,P11881,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0005955; GO:0032469; GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0005637; GO:0005730; GO:0035091; GO:0031088; GO:0031094; GO:0009791; GO:0014069; GO:0051209; GO:0001666; GO:0016529; GO:0050882,"calcineurin complex; endoplasmic reticulum calcium ion homeostasis; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; nuclear inner membrane; nucleolus; phosphatidylinositol binding; platelet dense granule membrane; platelet dense tubular network; post-embryonic development; postsynaptic density; release of sequestered calcium ion into cytosol; response to hypoxia; sarcoplasmic reticulum; voluntary musculoskeletal movement",PF08709;PF00520;PF02815;PF08454;PF01365;,0,CHOYP_LOC100533406.1.2,,,,,,,ITPR1_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of calcium-mediated signaling [GO:0050849]; post-embryonic development [GO:0009791]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; voluntary musculoskeletal movement [GO:0050882] comp134954_c0_seq2,2200,43,0.47246978,0,0,,0,Q8WSR4,"Inositol 1,4,5-trisphosphate receptor (ApIP3R)","Inositol 1,4,5-trisphosphate receptor (ApIP3R)",GO:0005789; GO:0005220; GO:0048016; GO:0016021; GO:0007275; GO:0007338,"endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; inositol phosphate-mediated signaling; integral to membrane; multicellular organismal development; single fertilization",PF08709;PF00520;PF02815;PF08454;PF01365;,,,,,,,,,ITPR_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),multicellular organism development [GO:0007275]; single fertilization [GO:0007338] comp134954_c0_seq3,930,45.6989,0.39174869,0,0,,,,,,,,,4.00E-110,CHOYP_LOC100533406.2.2,,,,,,,,, comp134954_c0_seq4,2134,42.9241,0.46837379,0,0,,0,Q14571,"Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)",GO:0038095; GO:0038096; GO:0007202; GO:0005938; GO:0071320; GO:0071361; GO:0006112; GO:0007173; GO:0008543; GO:0045087; GO:0005220; GO:0016021; GO:0048011; GO:0035091; GO:0005886; GO:0030168; GO:0031095; GO:0050796; GO:0001666; GO:0033017; GO:0044281,"Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; activation of phospholipase C activity; cell cortex; cellular response to cAMP; cellular response to ethanol; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; neurotrophin TRK receptor signaling pathway; phosphatidylinositol binding; plasma membrane; platelet activation; platelet dense tubular network membrane; regulation of insulin secretion; response to hypoxia; sarcoplasmic reticulum membrane; small molecule metabolic process",PF08709;PF00520;PF02815;PF08454;PF01365;,0,CHOYP_LOC100533406.1.2,,,,,,,ITPR2_HUMAN,Homo sapiens (Human),cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; platelet activation [GO:0030168]; regulation of cardiac conduction [GO:1903779]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; transport [GO:0006810] comp134954_c0_seq5,2662,40.4959,0.47737183,0,0,,0,P11881,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0005955; GO:0032469; GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0005637; GO:0005730; GO:0035091; GO:0031088; GO:0031094; GO:0009791; GO:0014069; GO:0051209; GO:0001666; GO:0016529; GO:0050882,"calcineurin complex; endoplasmic reticulum calcium ion homeostasis; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; nuclear inner membrane; nucleolus; phosphatidylinositol binding; platelet dense granule membrane; platelet dense tubular network; post-embryonic development; postsynaptic density; release of sequestered calcium ion into cytosol; response to hypoxia; sarcoplasmic reticulum; voluntary musculoskeletal movement",PF08709;PF00520;PF02815;PF08454;PF01365;,0,CHOYP_LOC100533406.2.2,,,,,,,ITPR1_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of calcium-mediated signaling [GO:0050849]; post-embryonic development [GO:0009791]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; voluntary musculoskeletal movement [GO:0050882] comp134956_c0_seq2,1127,40.4614,0.37146263,16,124,,4.00E-20,Q7Z6J8,E3 ubiquitin-protein ligase E3D (EC 6.3.2.-) (UbcH10-binding protein with a HECT-like domain) (Ubiquitin-conjugating enzyme E2C-binding protein),E3 ubiquitin-protein ligase E3D (EC 6.3.2.-) (UbcH10-binding protein with a HECT-like domain) (Ubiquitin-conjugating enzyme E2C-binding protein),GO:0005737; GO:0016874; GO:0016567,cytoplasm; ligase activity; protein ubiquitination,PF09814;,,,,,,,,,UBE3D_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp134957_c0_seq1,2190,39.0411,0.43394741,164,1008,,4.00E-07,Q9UGU5,HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG),HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG),GO:0003677; GO:0016589; GO:0016055; GO:0008333; GO:0030178,DNA binding; NURF complex; Wnt receptor signaling pathway; endosome to lysosome transport; negative regulation of Wnt receptor signaling pathway,PF13775;PF00505;,,,,,,,,,HMGX4_HUMAN,Homo sapiens (Human),endosome to lysosome transport [GO:0008333]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp134957_c0_seq2,470,36.1702,0.39201176,98,324,,1.00E-20,Q9UGU5,HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG),HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG),GO:0003677; GO:0016589; GO:0016055; GO:0008333; GO:0030178,DNA binding; NURF complex; Wnt receptor signaling pathway; endosome to lysosome transport; negative regulation of Wnt receptor signaling pathway,PF13775;PF00505;,1.00E-17,CHOYP_HMGXB4.2.2,,,,,,,HMGX4_HUMAN,Homo sapiens (Human),endosome to lysosome transport [GO:0008333]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp134960_c0_seq1,1076,46.2825,0.68328729,4,0,,,,,,,,,2.00E-69,CHOYP_LOC100372992.1.2,5.00E-25,ruditapes_c4313,,,,,,, comp134960_c0_seq2,1540,45.8442,0.79353133,69,163,,7.00E-26,Q8BTI8,Serine/arginine repetitive matrix protein 2,Serine/arginine repetitive matrix protein 2,GO:0015030; GO:0008380; GO:0071013; GO:0006397; GO:0016607,Cajal body; RNA splicing; catalytic step 2 spliceosome; mRNA processing; nuclear speck,PF08312;,4.00E-68,CHOYP_LOC100372992.2.2,,,,,,,SRRM2_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp134962_c0_seq2,1938,37.1517,0.44962331,1247,149,,1.00E-69,Q96L03,Spermatogenesis-associated protein 17,Spermatogenesis-associated protein 17,GO:0005737,cytoplasm,PF00612;,3.00E-95,CHOYP_LOC576665.1.2,,,,,,,SPT17_HUMAN,Homo sapiens (Human), comp134967_c1_seq1,306,44.1176,0.61047934,8,88,,4.00E-06,Q56R14,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_XENLA,Xenopus laevis (African clawed frog),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp134971_c0_seq1,2675,42.243,0.69238716,18,0,,0,Q13698,"Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (Voltage-gated calcium channel subunit alpha Cav1.1)","Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (Voltage-gated calcium channel subunit alpha Cav1.1)",GO:0031674; GO:0030315; GO:0007411; GO:0007029; GO:0002074; GO:0008331; GO:0046872; GO:0006936; GO:0007520; GO:0007528; GO:0016529; GO:0043501; GO:0048741; GO:0001501; GO:0006941; GO:0005891,I band; T-tubule; axon guidance; endoplasmic reticulum organization; extraocular skeletal muscle development; high voltage-gated calcium channel activity; metal ion binding; muscle contraction; myoblast fusion; neuromuscular junction development; sarcoplasmic reticulum; skeletal muscle adaptation; skeletal muscle fiber development; skeletal system development; striated muscle contraction; voltage-gated calcium channel complex,PF08763;PF16905;PF00520;,,,,,,,,,CAC1S_HUMAN,Homo sapiens (Human),calcium ion transport [GO:0006816]; cardiac conduction [GO:0061337]; membrane depolarization during action potential [GO:0086010]; muscle contraction [GO:0006936] comp134971_c0_seq2,2453,42.8455,0.65298322,3,0,,8.00E-19,Q6Q760,Sodium leak channel non-selective protein (Four domain-type voltage-gated ion channel alpha-1 subunit) (Voltage gated channel-like protein 1),Sodium leak channel non-selective protein (Four domain-type voltage-gated ion channel alpha-1 subunit) (Voltage gated channel-like protein 1),GO:0016021; GO:0005272; GO:0035725; GO:0005244,integral to membrane; sodium channel activity; sodium ion transmembrane transport; voltage-gated ion channel activity,PF00520;,,,,,,,,,NALCN_RAT,Rattus norvegicus (Rat),calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010] comp134971_c0_seq3,1094,40.8592,0.85582137,2,0,,2.00E-08,Q91ZR5,Cation channel sperm-associated protein 1 (CatSper1),Cation channel sperm-associated protein 1 (CatSper1),GO:0036128; GO:0030154; GO:0001539; GO:0005929; GO:0007342; GO:0007275; GO:0051924; GO:0030317; GO:0007283; GO:0005245,CatSper complex; cell differentiation; ciliary or bacterial-type flagellar motility; cilium; fusion of sperm to egg plasma membrane; multicellular organismal development; regulation of calcium ion transport; sperm motility; spermatogenesis; voltage-gated calcium channel activity,PF00520;,2.00E-31,CHOYP_LOC100647135.2.2,,,,,,,CTSR1_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; fusion of sperm to egg plasma membrane [GO:0007342]; membrane depolarization during action potential [GO:0086010]; multicellular organism development [GO:0007275]; regulation of calcium ion transport [GO:0051924]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp134971_c0_seq4,2350,42.9787,0.66905941,2,0,,0,Q25452,Muscle calcium channel subunit alpha-1 (MDL-alpha-1),Muscle calcium channel subunit alpha-1 (MDL-alpha-1),GO:0046872; GO:0005245; GO:0005891,metal ion binding; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08763;PF16905;PF00520;,,,,,,,,,CAC1M_MUSDO,Musca domestica (House fly), comp134971_c0_seq5,1645,42.7964,0.64517417,134,63,,4.00E-157,Q02485,"Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (ROB1) (Voltage-gated calcium channel subunit alpha Cav1.1) (Fragment)","Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (ROB1) (Voltage-gated calcium channel subunit alpha Cav1.1) (Fragment)",GO:0008331; GO:0046872; GO:0001503; GO:0042383; GO:0005891,high voltage-gated calcium channel activity; metal ion binding; ossification; sarcolemma; voltage-gated calcium channel complex,PF08763;PF16885;PF16905;PF00520;,0,CHOYP_CAC1D.1.1,,,,,,,CAC1S_RAT,Rattus norvegicus (Rat),calcium ion transport [GO:0006816]; membrane depolarization during action potential [GO:0086010]; ossification [GO:0001503] comp134971_c0_seq6,1450,41.3793,0.68230698,4,0,,8.00E-179,Q25452,Muscle calcium channel subunit alpha-1 (MDL-alpha-1),Muscle calcium channel subunit alpha-1 (MDL-alpha-1),GO:0046872; GO:0005245; GO:0005891,metal ion binding; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08763;PF16905;PF00520;,0,CHOYP_CAC1D.1.1,,,,,,,CAC1M_MUSDO,Musca domestica (House fly), comp134974_c0_seq1,1390,42.6619,0.55386832,21,8,,3.00E-09,Q8NCF5,"NFATC2-interacting protein (45 kDa NF-AT-interacting protein) (45 kDa NFAT-interacting protein) (Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein)","NFATC2-interacting protein (45 kDa NF-AT-interacting protein) (45 kDa NFAT-interacting protein) (Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein)",GO:0001816; GO:0005737; GO:0005634; GO:0006355,"cytokine production; cytoplasm; nucleus; regulation of transcription, DNA-dependent",PF11976;,,,,,,,,,NF2IP_HUMAN,Homo sapiens (Human),cytokine production [GO:0001816]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein sumoylation [GO:0016925] comp134975_c2_seq1,1846,41.2784,0.48030526,0,0,,2.00E-18,P42232,Signal transducer and activator of transcription 5B,Signal transducer and activator of transcription 5B,GO:0006103; GO:0060397; GO:0048541; GO:0000979; GO:0033077; GO:0043029; GO:0000255; GO:0005509; GO:0006101; GO:0006600; GO:0046449; GO:0005829; GO:0046543; GO:0046544; GO:0006631; GO:0007565; GO:0006549; GO:0007595; GO:0019915; GO:0001553; GO:0001779; GO:0043066; GO:0045647; GO:0005634; GO:0006107; GO:0045579; GO:0042104; GO:0045588; GO:0050729; GO:0045086; GO:0045931; GO:0040018; GO:0032825; GO:0045954; GO:0032819; GO:0045944; GO:0042448; GO:0038161; GO:0030155; GO:0030856; GO:0019218; GO:0032355; GO:0070672; GO:0070669; GO:0070670; GO:0003700; GO:0004871; GO:0006105; GO:0019530; GO:0006351; GO:0006573,"2-oxoglutarate metabolic process; JAK-STAT cascade involved in growth hormone signaling pathway; Peyer's patch development; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation in thymus; T cell homeostasis; allantoin metabolic process; calcium ion binding; citrate metabolic process; creatine metabolic process; creatinine metabolic process; cytosol; development of secondary female sexual characteristics; development of secondary male sexual characteristics; fatty acid metabolic process; female pregnancy; isoleucine metabolic process; lactation; lipid storage; luteinization; natural killer cell differentiation; negative regulation of apoptotic process; negative regulation of erythrocyte differentiation; nucleus; oxaloacetate metabolic process; positive regulation of B cell differentiation; positive regulation of activated T cell proliferation; positive regulation of gamma-delta T cell differentiation; positive regulation of inflammatory response; positive regulation of interleukin-2 biosynthetic process; positive regulation of mitotic cell cycle; positive regulation of multicellular organism growth; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell proliferation; positive regulation of transcription from RNA polymerase II promoter; progesterone metabolic process; prolactin signaling pathway; regulation of cell adhesion; regulation of epithelial cell differentiation; regulation of steroid metabolic process; response to estradiol stimulus; response to interleukin-15; response to interleukin-2; response to interleukin-4; sequence-specific DNA binding transcription factor activity; signal transducer activity; succinate metabolic process; taurine metabolic process; transcription, DNA-dependent; valine metabolic process",PF00017;PF01017;PF02864;PF02865;,,,,,,,,,STA5B_MOUSE,Mus musculus (Mouse),2-oxoglutarate metabolic process [GO:0006103]; acute-phase response [GO:0006953]; allantoin metabolic process [GO:0000255]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; citrate metabolic process [GO:0006101]; creatine metabolic process [GO:0006600]; creatinine metabolic process [GO:0046449]; cytokine-mediated signaling pathway [GO:0019221]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; fatty acid metabolic process [GO:0006631]; female pregnancy [GO:0007565]; isoleucine metabolic process [GO:0006549]; JAK-STAT cascade [GO:0007259]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; liver development [GO:0001889]; luteinization [GO:0001553]; mast cell migration [GO:0097531]; natural killer cell differentiation [GO:0001779]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; oxaloacetate metabolic process [GO:0006107]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; progesterone metabolic process [GO:0042448]; prolactin signaling pathway [GO:0038161]; regulation of cell adhesion [GO:0030155]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to lipopolysaccharide [GO:0032496]; sex differentiation [GO:0007548]; succinate metabolic process [GO:0006105]; taurine metabolic process [GO:0019530]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; valine metabolic process [GO:0006573] comp134975_c2_seq4,2968,42.5539,0.40323242,0,0,,3.00E-20,Q9NAD6,Signal transducer and activator of transcription 1,Signal transducer and activator of transcription 1,GO:0005509; GO:0005737; GO:0040024; GO:0005634; GO:0043565; GO:0003700; GO:0004871; GO:0006351,"calcium ion binding; cytoplasm; dauer larval development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription, DNA-dependent",PF00017;PF01017;PF02864;,,,,,,,,,STAT1_CAEEL,Caenorhabditis elegans,"dauer larval development [GO:0040024]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp134975_c2_seq6,2307,44.1266,0.39226691,0,0,,8.00E-19,P42226,Signal transducer and activator of transcription 6 (IL-4 Stat),Signal transducer and activator of transcription 6 (IL-4 Stat),GO:0000979; GO:0002296; GO:0005509; GO:0005829; GO:0045087; GO:0035771; GO:0033598; GO:0060443; GO:0000122; GO:0002829; GO:0000790; GO:0005654; GO:0048295; GO:0045944; GO:0032481; GO:0042127; GO:0006357; GO:0003700; GO:0004871; GO:0006351,"RNA polymerase II core promoter sequence-specific DNA binding; T-helper 1 cell lineage commitment; calcium ion binding; cytosol; innate immune response; interleukin-4-mediated signaling pathway; mammary gland epithelial cell proliferation; mammary gland morphogenesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of type 2 immune response; nuclear chromatin; nucleoplasm; positive regulation of isotype switching to IgE isotypes; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type I interferon production; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription, DNA-dependent",PF00017;PF14596;PF01017;PF02864;PF02865;,,,,,,,,,STAT6_HUMAN,Homo sapiens (Human),"cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; interleukin-4-mediated signaling pathway [GO:0035771]; mammary gland epithelial cell proliferation [GO:0033598]; mammary gland morphogenesis [GO:0060443]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of type 2 immune response [GO:0002829]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of cell proliferation [GO:0042127]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction [GO:0007165]; T-helper 1 cell lineage commitment [GO:0002296]; transcription, DNA-templated [GO:0006351]" comp134975_c2_seq7,3086,42.6118,0.41049962,0,0,,2.00E-21,P52632,Signal transducer and activator of transcription 5B,Signal transducer and activator of transcription 5B,GO:0006103; GO:0007259; GO:0060397; GO:0048541; GO:0000979; GO:0033077; GO:0043029; GO:0006953; GO:0000255; GO:0005509; GO:0006101; GO:0006600; GO:0046449; GO:0005829; GO:0046543; GO:0046544; GO:0003690; GO:0006631; GO:0007565; GO:0006549; GO:0007595; GO:0019915; GO:0001889; GO:0001553; GO:0001779; GO:0043066; GO:0045647; GO:0005634; GO:0006107; GO:0045579; GO:0042104; GO:0051272; GO:0045588; GO:0050729; GO:0045086; GO:0045931; GO:0040018; GO:0032825; GO:0045954; GO:0032819; GO:0048661; GO:0045944; GO:0042448; GO:0038161; GO:0030155; GO:0030856; GO:0019218; GO:0032355; GO:0045471; GO:0001666; GO:0070672; GO:0070669; GO:0070670; GO:0032496; GO:0043434; GO:0043565; GO:0003700; GO:0004871; GO:0006105; GO:0019530; GO:0006366; GO:0006573,2-oxoglutarate metabolic process; JAK-STAT cascade; JAK-STAT cascade involved in growth hormone signaling pathway; Peyer's patch development; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation in thymus; T cell homeostasis; acute-phase response; allantoin metabolic process; calcium ion binding; citrate metabolic process; creatine metabolic process; creatinine metabolic process; cytosol; development of secondary female sexual characteristics; development of secondary male sexual characteristics; double-stranded DNA binding; fatty acid metabolic process; female pregnancy; isoleucine metabolic process; lactation; lipid storage; liver development; luteinization; natural killer cell differentiation; negative regulation of apoptotic process; negative regulation of erythrocyte differentiation; nucleus; oxaloacetate metabolic process; positive regulation of B cell differentiation; positive regulation of activated T cell proliferation; positive regulation of cellular component movement; positive regulation of gamma-delta T cell differentiation; positive regulation of inflammatory response; positive regulation of interleukin-2 biosynthetic process; positive regulation of mitotic cell cycle; positive regulation of multicellular organism growth; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell proliferation; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; progesterone metabolic process; prolactin signaling pathway; regulation of cell adhesion; regulation of epithelial cell differentiation; regulation of steroid metabolic process; response to estradiol stimulus; response to ethanol; response to hypoxia; response to interleukin-15; response to interleukin-2; response to interleukin-4; response to lipopolysaccharide; response to peptide hormone stimulus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; succinate metabolic process; taurine metabolic process; transcription from RNA polymerase II promoter; valine metabolic process,PF00017;PF01017;PF02864;PF02865;,,,,,,,,,STA5B_RAT,Rattus norvegicus (Rat),"acute-phase response [GO:0006953]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; JAK-STAT cascade [GO:0007259]; liver development [GO:0001889]; luteinization [GO:0001553]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prolactin signaling pathway [GO:0038161]; regulation of transcription, DNA-templated [GO:0006355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; transcription from RNA polymerase II promoter [GO:0006366]" comp134975_c2_seq8,3747,41.6333,0.41724783,0,0,,3.00E-21,P52632,Signal transducer and activator of transcription 5B,Signal transducer and activator of transcription 5B,GO:0006103; GO:0007259; GO:0060397; GO:0048541; GO:0000979; GO:0033077; GO:0043029; GO:0006953; GO:0000255; GO:0005509; GO:0006101; GO:0006600; GO:0046449; GO:0005829; GO:0046543; GO:0046544; GO:0003690; GO:0006631; GO:0007565; GO:0006549; GO:0007595; GO:0019915; GO:0001889; GO:0001553; GO:0001779; GO:0043066; GO:0045647; GO:0005634; GO:0006107; GO:0045579; GO:0042104; GO:0051272; GO:0045588; GO:0050729; GO:0045086; GO:0045931; GO:0040018; GO:0032825; GO:0045954; GO:0032819; GO:0048661; GO:0045944; GO:0042448; GO:0038161; GO:0030155; GO:0030856; GO:0019218; GO:0032355; GO:0045471; GO:0001666; GO:0070672; GO:0070669; GO:0070670; GO:0032496; GO:0043434; GO:0043565; GO:0003700; GO:0004871; GO:0006105; GO:0019530; GO:0006366; GO:0006573,2-oxoglutarate metabolic process; JAK-STAT cascade; JAK-STAT cascade involved in growth hormone signaling pathway; Peyer's patch development; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation in thymus; T cell homeostasis; acute-phase response; allantoin metabolic process; calcium ion binding; citrate metabolic process; creatine metabolic process; creatinine metabolic process; cytosol; development of secondary female sexual characteristics; development of secondary male sexual characteristics; double-stranded DNA binding; fatty acid metabolic process; female pregnancy; isoleucine metabolic process; lactation; lipid storage; liver development; luteinization; natural killer cell differentiation; negative regulation of apoptotic process; negative regulation of erythrocyte differentiation; nucleus; oxaloacetate metabolic process; positive regulation of B cell differentiation; positive regulation of activated T cell proliferation; positive regulation of cellular component movement; positive regulation of gamma-delta T cell differentiation; positive regulation of inflammatory response; positive regulation of interleukin-2 biosynthetic process; positive regulation of mitotic cell cycle; positive regulation of multicellular organism growth; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell proliferation; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; progesterone metabolic process; prolactin signaling pathway; regulation of cell adhesion; regulation of epithelial cell differentiation; regulation of steroid metabolic process; response to estradiol stimulus; response to ethanol; response to hypoxia; response to interleukin-15; response to interleukin-2; response to interleukin-4; response to lipopolysaccharide; response to peptide hormone stimulus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; succinate metabolic process; taurine metabolic process; transcription from RNA polymerase II promoter; valine metabolic process,PF00017;PF01017;PF02864;PF02865;,,,,,,,,,STA5B_RAT,Rattus norvegicus (Rat),"acute-phase response [GO:0006953]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; JAK-STAT cascade [GO:0007259]; liver development [GO:0001889]; luteinization [GO:0001553]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prolactin signaling pathway [GO:0038161]; regulation of transcription, DNA-templated [GO:0006355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; transcription from RNA polymerase II promoter [GO:0006366]" comp134976_c0_seq1,1535,42.4756,0.52338382,751,2578,,9.00E-28,Q91W67,Ubiquitin-like protein 7,Ubiquitin-like protein 7,,,PF00627;PF00240;,,,3.00E-17,ruditapes_c26437,,,,,UBL7_MOUSE,Mus musculus (Mouse), comp134980_c0_seq1,1624,34.8522,0.66956786,119,474,,1.00E-97,Q3U4G3,"Xyloside xylosyltransferase 1 (EC 2.4.2.n3) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase)","Xyloside xylosyltransferase 1 (EC 2.4.2.n3) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase)",GO:0005789; GO:0016021; GO:0016763,"endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring pentosyl groups",PF01501;,,,,,,,,,XXLT1_MOUSE,Mus musculus (Mouse), comp134981_c0_seq2,501,50.0998,0.61070803,22,3,,9.00E-44,B1AVY7,Kinesin-like protein KIF16B,Kinesin-like protein KIF16B,GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,,,,,,,,,KI16B_MOUSE,Mus musculus (Mouse),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp134981_c2_seq1,2239,46.8959,0.47090768,119,118,,3.00E-130,Q15058,Kinesin-like protein KIF14,Kinesin-like protein KIF14,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005634; GO:0005819,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; nucleus; spindle,PF00498;PF00225;PF16183;,1.00E-113,CHOYP_LOC100371468.2.2,,,,,,,KIF14_HUMAN,Homo sapiens (Human),activation of protein kinase activity [GO:0032147]; cell division [GO:0051301]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebellar granular layer structural organization [GO:0021685]; cerebellar Purkinje cell layer structural organization [GO:0021693]; cerebral cortex development [GO:0021987]; cytoskeleton-dependent intracellular transport [GO:0030705]; establishment of protein localization [GO:0045184]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; mitotic cell cycle process [GO:1903047]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of integrin activation [GO:0033624]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory bulb development [GO:0021772]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell maturation [GO:1903429]; regulation of cell migration [GO:0030334]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of myelination [GO:0031641]; regulation of neuron apoptotic process [GO:0043523]; regulation of Rap protein signal transduction [GO:0032487]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; substrate adhesion-dependent cell spreading [GO:0034446] comp134985_c1_seq1,2747,42.3007,0.37454005,2,0,,2.00E-130,Q9WVR8,Menin,Menin,GO:0003677; GO:0007420; GO:0016568; GO:0005634; GO:0032925; GO:0006355; GO:0006351,"DNA binding; brain development; chromatin modification; nucleus; regulation of activin receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05053;,,,,,,,,,MEN1_RAT,Rattus norvegicus (Rat),"brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose stimulus [GO:0071333]; cellular response to peptide hormone stimulus [GO:0071375]; decidualization [GO:0046697]; histone lysine methylation [GO:0034968]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to gamma radiation [GO:0010332]; response to transforming growth factor beta [GO:0071559]; response to UV [GO:0009411]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell differentiation [GO:0003309]" comp134985_c1_seq3,2766,42.4801,0.37674567,8,0,,,,,,,,,8.00E-105,CHOYP_LOC589807.1.1,,,,,,,,, comp134985_c1_seq4,439,37.3576,0.46645706,0,4,,9.00E-30,Q0P5I0,Menin,Menin,GO:0000165; GO:0000403; GO:0007050; GO:0000785; GO:0003682; GO:0006338; GO:0032154; GO:0005829; GO:0003690; GO:0048704; GO:0000400; GO:0030097; GO:0035097; GO:0018024; GO:0001776; GO:0060135; GO:0046329; GO:0008285; GO:0045736; GO:0046621; GO:0045668; GO:0043433; GO:0051974; GO:0000122; GO:0016363; GO:0002076; GO:0002051; GO:0060021; GO:0043065; GO:0051781; GO:0043280; GO:0031062; GO:0045669; GO:0032092; GO:0045944; GO:0030511; GO:0006974; GO:0009411; GO:0010332; GO:0043565; GO:0044212; GO:0006351,"MAPK cascade; Y-form DNA binding; cell cycle arrest; chromatin; chromatin binding; chromatin remodeling; cleavage furrow; cytosol; double-stranded DNA binding; embryonic skeletal system morphogenesis; four-way junction DNA binding; hemopoiesis; histone methyltransferase complex; histone-lysine N-methyltransferase activity; leukocyte homeostasis; maternal process involved in female pregnancy; negative regulation of JNK cascade; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of organ growth; negative regulation of osteoblast differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of telomerase activity; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; osteoblast development; osteoblast fate commitment; palate development; positive regulation of apoptotic process; positive regulation of cell division; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of histone methylation; positive regulation of osteoblast differentiation; positive regulation of protein binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; response to DNA damage stimulus; response to UV; response to gamma radiation; sequence-specific DNA binding; transcription regulatory region DNA binding; transcription, DNA-dependent",PF05053;,,,,,,,,,MEN1_BOVIN,Bos taurus (Bovine),"cellular response to DNA damage stimulus [GO:0006974]; histone lysine methylation [GO:0034968]; MAPK cascade [GO:0000165]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of protein binding [GO:0032092]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to gamma radiation [GO:0010332]; response to UV [GO:0009411]; transcription, DNA-templated [GO:0006351]" comp134986_c1_seq1,1526,39.8427,0.69127858,0,0,,9.00E-08,Q92569,Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),GO:0016303; GO:0005829; GO:0008286; GO:0005942; GO:0035014; GO:0043551; GO:0044281,1-phosphatidylinositol-3-kinase activity; cytosol; insulin receptor signaling pathway; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity; small molecule metabolic process,PF16454;PF00017;,,,,,,,,,P55G_HUMAN,Homo sapiens (Human),insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] comp134986_c1_seq10,2320,40.5603,0.52986522,0,0,,1.00E-63,Q08DN7,Proto-oncogene vav,Proto-oncogene vav,GO:0005089; GO:0035556; GO:0046872; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; intracellular signal transduction; metal ion binding; phospholipid binding; regulation of Rho protein signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;,,,,,,,,,VAV_BOVIN,Bos taurus (Bovine),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq11,1468,43.5286,0.50471212,0,0,,8.00E-48,P15498,Proto-oncogene vav,Proto-oncogene vav,GO:0038095; GO:0038096; GO:0030676; GO:0042110; GO:0031295; GO:0097190; GO:0005829; GO:0007173; GO:0008543; GO:0005085; GO:0045087; GO:0007229; GO:0046872; GO:0048011; GO:0048015; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0045785; GO:0043087; GO:0035023; GO:0051056; GO:0003700; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rac guanyl-nucleotide exchange factor activity; T cell activation; T cell costimulation; apoptotic signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; guanyl-nucleotide exchange factor activity; innate immune response; integrin-mediated signaling pathway; metal ion binding; neurotrophin TRK receptor signaling pathway; phosphatidylinositol-mediated signaling; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of cell adhesion; regulation of GTPase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; sequence-specific DNA binding transcription factor activity; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;,2.00E-14,CHOYP_VAV2.2.3,,,,,,,VAV_HUMAN,Homo sapiens (Human),Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq12,2388,41.4154,0.55310538,0,0,,7.00E-67,Q60992,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0005089; GO:0001525; GO:0016477; GO:0005829; GO:0005085; GO:0030032; GO:0046872; GO:0005543; GO:0005886; GO:0043552; GO:0035023; GO:0007264,Rho guanyl-nucleotide exchange factor activity; angiogenesis; cell migration; cytosol; guanyl-nucleotide exchange factor activity; lamellipodium assembly; metal ion binding; phospholipid binding; plasma membrane; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell migration [GO:0016477]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq13,2670,41.0487,0.52151292,0,0,,1.00E-68,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq14,2734,41.0022,0.51949334,0,0,,1.00E-08,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,,,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp134986_c1_seq15,2365,39.4926,0.50459933,0,0,,2.00E-13,Q6YKA8,Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk),Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk),GO:0005070; GO:0005886; GO:0004871,SH3/SH2 adaptor activity; plasma membrane; signal transducer activity,PF00017;PF00018;,,,,,,,,,DRK_DROSI,Drosophila simulans (Fruit fly), comp134986_c1_seq17,1973,43.7912,0.53160848,0,0,,6.00E-106,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,2.00E-55,CHOYP_VAV2.2.3,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq18,1676,38.3055,0.59660864,0,0,,9.00E-19,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq19,2202,40.7357,0.5657195,0,0,,1.00E-08,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,,,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp134986_c1_seq2,2307,40.6589,0.53066997,0,0,,8.00E-66,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq20,2433,40.3617,0.53095735,0,0,,5.00E-12,A6QLK6,GRB2-related adapter protein,GRB2-related adapter protein,,,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_BOVIN,Bos taurus (Bovine), comp134986_c1_seq22,2484,40.4187,0.52921638,0,0,,8.00E-08,Q8UUU2,Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),GO:0005943; GO:0043125; GO:0005158; GO:0008286; GO:0043560; GO:0005159; GO:0048009; GO:0035014; GO:0046854,"1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ErbB-3 class receptor binding; insulin receptor binding; insulin receptor signaling pathway; insulin receptor substrate binding; insulin-like growth factor receptor binding; insulin-like growth factor receptor signaling pathway; phosphatidylinositol 3-kinase regulator activity; phosphatidylinositol phosphorylation",PF16454;PF00620;PF00017;,,,,,,,,,P85AA_XENLA,Xenopus laevis (African clawed frog),cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] comp134986_c1_seq23,2893,41.9634,0.5647606,0,0,,7.00E-122,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,2.00E-55,CHOYP_VAV2.2.3,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq24,2151,40.6788,0.56857825,0,0,,1.00E-14,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq25,1770,39.322,0.62372247,0,0,,2.00E-08,P10686,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0005509; GO:0006816; GO:0071364; GO:0005737; GO:0032959; GO:0005158; GO:0035556; GO:0030027; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0010634; GO:0009306; GO:1901339; GO:0009629; GO:0042542; GO:0043278; GO:0001726; GO:0004871; GO:0007165,COP9 signalosome; calcium ion binding; calcium ion transport; cellular response to epidermal growth factor stimulus; cytoplasm; inositol trisphosphate biosynthetic process; insulin receptor binding; intracellular signal transduction; lamellipodium; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; positive regulation of epithelial cell migration; protein secretion; regulation of store-operated calcium channel activity; response to gravity; response to hydrogen peroxide; response to morphine; ruffle; signal transducer activity; signal transduction,PF00168;PF00388;PF00387;PF00017;PF00018;,,,,,,,,,PLCG1_RAT,Rattus norvegicus (Rat),activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; cellular response to epidermal growth factor stimulus [GO:0071364]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to gravity [GO:0009629]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165] comp134986_c1_seq26,2683,40.9616,0.52086868,0,0,,1.00E-68,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq27,2721,41.0878,0.52013869,0,0,,1.00E-46,P54100,Proto-oncogene vav (p95),Proto-oncogene vav (p95),GO:0005089; GO:0048468; GO:0005085; GO:0002768; GO:0035556; GO:0046872; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell development; guanyl-nucleotide exchange factor activity; immune response-regulating cell surface receptor signaling pathway; intracellular signal transduction; metal ion binding; phospholipid binding; regulation of Rho protein signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;PF07653;,,,,,,,,,VAV_RAT,Rattus norvegicus (Rat),cell development [GO:0048468]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq28,2083,39.7024,0.54229121,0,0,,3.00E-21,Q45FX5,Protein vav-1,Protein vav-1,GO:0005089; GO:0035556; GO:0046872; GO:0045746; GO:0005543; GO:0035023; GO:0040028,Rho guanyl-nucleotide exchange factor activity; intracellular signal transduction; metal ion binding; negative regulation of Notch signaling pathway; phospholipid binding; regulation of Rho protein signal transduction; regulation of vulval development,PF00130;PF00307;PF00169;PF00621;PF00017;PF07653;,1.00E-12,CHOYP_VAV2.2.3,,,,,,,VAV_CAEEL,Caenorhabditis elegans,intracellular signal transduction [GO:0035556]; negative regulation of Notch signaling pathway [GO:0045746]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vulval development [GO:0040028] comp134986_c1_seq29,1808,39.5465,0.62004419,0,0,,1.00E-07,Q92569,Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),GO:0016303; GO:0005829; GO:0008286; GO:0005942; GO:0035014; GO:0043551; GO:0044281,1-phosphatidylinositol-3-kinase activity; cytosol; insulin receptor signaling pathway; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity; small molecule metabolic process,PF16454;PF00017;,,,,,,,,,P55G_HUMAN,Homo sapiens (Human),insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] comp134986_c1_seq3,2497,40.3284,0.52843045,0,0,,1.00E-08,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,,,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp134986_c1_seq30,2439,41.4514,0.55092107,0,0,,8.00E-08,Q8UUU2,Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),GO:0005943; GO:0043125; GO:0005158; GO:0008286; GO:0043560; GO:0005159; GO:0048009; GO:0035014; GO:0046854,"1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ErbB-3 class receptor binding; insulin receptor binding; insulin receptor signaling pathway; insulin receptor substrate binding; insulin-like growth factor receptor binding; insulin-like growth factor receptor signaling pathway; phosphatidylinositol 3-kinase regulator activity; phosphatidylinositol phosphorylation",PF16454;PF00620;PF00017;,,,,,,,,,P85AA_XENLA,Xenopus laevis (African clawed frog),cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] comp134986_c1_seq31,2446,40.2698,0.53017017,0,0,,1.00E-07,Q5R685,Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),GO:0005942; GO:0035014; GO:0043551; GO:0007165,phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity; signal transduction,PF16454;PF00620;PF00017;,,,,,,,,,P85A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165] comp134986_c1_seq32,555,42.5225,0.75891051,0,0,,4.00E-09,Q66II3,Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2),Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2),GO:0005794; GO:0005768; GO:0005154; GO:0008286; GO:0043560; GO:0007126; GO:0007275; GO:0005634,Golgi apparatus; endosome; epidermal growth factor receptor binding; insulin receptor signaling pathway; insulin receptor substrate binding; meiosis; multicellular organismal development; nucleus,PF00017;PF00018;,,,,,,,,,GRB2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),insulin receptor signaling pathway [GO:0008286]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275] comp134986_c1_seq33,2164,40.573,0.56765754,0,0,,1.00E-08,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,1.00E-12,CHOYP_VAV2.2.3,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp134986_c1_seq34,1689,38.1883,0.59481465,0,0,,9.00E-19,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq35,3239,41.556,0.53619236,0,0,,8.00E-120,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,2.00E-55,CHOYP_VAV2.2.3,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq36,1282,42.6677,0.51581377,0,0,,4.00E-09,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,,,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp134986_c1_seq37,1053,43.5897,0.38173881,0,0,,1.00E-06,Q9Z0R4,Intersectin-1 (EH and SH3 domains protein 1),Intersectin-1 (EH and SH3 domains protein 1),GO:0005089; GO:0005509; GO:0030054; GO:0005905; GO:0030139; GO:0006897; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0005543; GO:0005886; GO:0051897; GO:0035023; GO:0007264; GO:0045202,Rho guanyl-nucleotide exchange factor activity; calcium ion binding; cell junction; coated pit; endocytic vesicle; endocytosis; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; phospholipid binding; plasma membrane; positive regulation of protein kinase B signaling cascade; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; synapse,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,,,,,,,,,ITSN1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq38,2352,39.5833,0.50545447,0,0,,2.00E-17,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq4,1407,38.2374,0.67363715,0,0,,5.00E-19,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq40,2024,43.7747,0.52955034,0,0,,1.00E-100,P15498,Proto-oncogene vav,Proto-oncogene vav,GO:0038095; GO:0038096; GO:0030676; GO:0042110; GO:0031295; GO:0097190; GO:0005829; GO:0007173; GO:0008543; GO:0005085; GO:0045087; GO:0007229; GO:0046872; GO:0048011; GO:0048015; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0045785; GO:0043087; GO:0035023; GO:0051056; GO:0003700; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rac guanyl-nucleotide exchange factor activity; T cell activation; T cell costimulation; apoptotic signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; guanyl-nucleotide exchange factor activity; innate immune response; integrin-mediated signaling pathway; metal ion binding; neurotrophin TRK receptor signaling pathway; phosphatidylinositol-mediated signaling; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of cell adhesion; regulation of GTPase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; sequence-specific DNA binding transcription factor activity; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;,2.00E-55,CHOYP_VAV2.2.3,,,,,,,VAV_HUMAN,Homo sapiens (Human),Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq41,1488,39.5833,0.69804541,0,0,,3.00E-12,P87379,Growth factor receptor-bound protein 2-A (Adapter protein GRB2-A) (SH2/SH3 adapter GRB2-A),Growth factor receptor-bound protein 2-A (Adapter protein GRB2-A) (SH2/SH3 adapter GRB2-A),GO:0005794; GO:0005768; GO:0005154; GO:0007143; GO:0008286; GO:0043560; GO:0007275; GO:0005634,Golgi apparatus; endosome; epidermal growth factor receptor binding; female meiosis; insulin receptor signaling pathway; insulin receptor substrate binding; multicellular organismal development; nucleus,PF00017;PF00018;,,,,,,,,,GRB2A_XENLA,Xenopus laevis (African clawed frog),female meiotic division [GO:0007143]; insulin receptor signaling pathway [GO:0008286]; multicellular organism development [GO:0007275] comp134986_c1_seq42,3175,41.6063,0.53810774,0,0,,5.00E-121,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq43,1475,39.7288,0.70012365,0,0,,2.00E-08,P10686,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0005509; GO:0006816; GO:0071364; GO:0005737; GO:0032959; GO:0005158; GO:0035556; GO:0030027; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0010634; GO:0009306; GO:1901339; GO:0009629; GO:0042542; GO:0043278; GO:0001726; GO:0004871; GO:0007165,COP9 signalosome; calcium ion binding; calcium ion transport; cellular response to epidermal growth factor stimulus; cytoplasm; inositol trisphosphate biosynthetic process; insulin receptor binding; intracellular signal transduction; lamellipodium; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; positive regulation of epithelial cell migration; protein secretion; regulation of store-operated calcium channel activity; response to gravity; response to hydrogen peroxide; response to morphine; ruffle; signal transducer activity; signal transduction,PF00168;PF00388;PF00387;PF00017;PF00018;,,,,,,,,,PLCG1_RAT,Rattus norvegicus (Rat),activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; cellular response to epidermal growth factor stimulus [GO:0071364]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to gravity [GO:0009629]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165] comp134986_c1_seq44,2812,41.3585,0.54789951,0,0,,2.00E-117,Q08DN7,Proto-oncogene vav,Proto-oncogene vav,GO:0005089; GO:0035556; GO:0046872; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; intracellular signal transduction; metal ion binding; phospholipid binding; regulation of Rho protein signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;,,,,,,,,,VAV_BOVIN,Bos taurus (Bovine),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq45,2906,41.8789,0.56415751,0,0,,7.00E-122,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,3.00E-48,CHOYP_VAV2.1.3,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq46,1394,38.3788,0.67612294,0,0,,5.00E-19,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq47,2944,41.9837,0.56282854,0,0,,8.00E-19,Q8TCU6,"Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)","Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)",GO:0005100; GO:0005089; GO:0030041; GO:0005829; GO:0043198; GO:0019899; GO:0030426; GO:0043231; GO:0035556; GO:0042119; GO:0048471; GO:0005543; GO:0005886; GO:0030833; GO:0050773; GO:0006801,Rho GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin filament polymerization; cytosol; dendritic shaft; enzyme binding; growth cone; intracellular membrane-bounded organelle; intracellular signal transduction; neutrophil activation; perinuclear region of cytoplasm; phospholipid binding; plasma membrane; regulation of actin filament polymerization; regulation of dendrite development; superoxide metabolic process,PF00610;PF00621;,2.00E-55,CHOYP_VAV2.2.3,,,,,,,PREX1_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin filament polymerization [GO:0030833]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]; superoxide metabolic process [GO:0006801]; T cell differentiation [GO:0030217] comp134986_c1_seq48,2070,39.8068,0.54331365,0,0,,1.00E-17,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq49,1539,39.7011,0.68924141,0,0,,2.00E-06,O00459,Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta),Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta),GO:0038095; GO:0038096; GO:0050852; GO:0007596; GO:0005829; GO:0007173; GO:0008543; GO:0045087; GO:0008286; GO:0050900; GO:0048011; GO:0005942; GO:0035014; GO:0036092; GO:0048015; GO:0043551; GO:0051056; GO:0007264; GO:0044281,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell receptor signaling pathway; blood coagulation; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; insulin receptor signaling pathway; leukocyte migration; neurotrophin TRK receptor signaling pathway; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; phosphatidylinositol-3-phosphate biosynthetic process; phosphatidylinositol-mediated signaling; regulation of phosphatidylinositol 3-kinase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; small molecule metabolic process,PF16454;PF00620;PF00017;,,,,,,,,,P85B_HUMAN,Homo sapiens (Human),cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein transport [GO:0015031]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to endoplasmic reticulum stress [GO:0034976]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq5,2215,40.6321,0.56480054,0,0,,1.00E-08,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,,,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp134986_c1_seq50,3188,41.5307,0.53756298,0,0,,5.00E-121,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,3.00E-48,CHOYP_VAV2.1.3,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq51,1821,39.4289,0.6184952,0,0,,1.00E-07,Q92569,Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),GO:0016303; GO:0005829; GO:0008286; GO:0005942; GO:0035014; GO:0043551; GO:0044281,1-phosphatidylinositol-3-kinase activity; cytosol; insulin receptor signaling pathway; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity; small molecule metabolic process,PF16454;PF00017;,,,,,,,,,P55G_HUMAN,Homo sapiens (Human),insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] comp134986_c1_seq52,3226,41.6305,0.53673815,0,0,,4.00E-99,P54100,Proto-oncogene vav (p95),Proto-oncogene vav (p95),GO:0005089; GO:0048468; GO:0005085; GO:0002768; GO:0035556; GO:0046872; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell development; guanyl-nucleotide exchange factor activity; immune response-regulating cell surface receptor signaling pathway; intracellular signal transduction; metal ion binding; phospholipid binding; regulation of Rho protein signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;PF07653;,,,,,,,,,VAV_RAT,Rattus norvegicus (Rat),cell development [GO:0048468]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq53,3094,41.0472,0.52096398,0,0,,7.00E-117,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq54,2825,41.2743,0.54724374,0,0,,4.00E-115,P54100,Proto-oncogene vav (p95),Proto-oncogene vav (p95),GO:0005089; GO:0048468; GO:0005085; GO:0002768; GO:0035556; GO:0046872; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell development; guanyl-nucleotide exchange factor activity; immune response-regulating cell surface receptor signaling pathway; intracellular signal transduction; metal ion binding; phospholipid binding; regulation of Rho protein signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;PF07653;,2.00E-55,CHOYP_VAV2.2.3,,,,,,,VAV_RAT,Rattus norvegicus (Rat),cell development [GO:0048468]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp134986_c1_seq55,816,42.2794,0.35801982,0,0,,5.00E-07,O42287,Intersectin-1,Intersectin-1,GO:0005509; GO:0030054; GO:0006897; GO:0012505; GO:0016020; GO:0043005; GO:0045202,calcium ion binding; cell junction; endocytosis; endomembrane system; membrane; neuron projection; synapse,PF12763;PF00018;PF07653;PF14604;,,,,,,,,,ITSN1_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897] comp134986_c1_seq56,1558,43.9024,0.45693665,0,0,,1.00E-19,Q8TCU6,"Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)","Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)",GO:0005100; GO:0005089; GO:0030041; GO:0005829; GO:0043198; GO:0019899; GO:0030426; GO:0043231; GO:0035556; GO:0042119; GO:0048471; GO:0005543; GO:0005886; GO:0030833; GO:0050773; GO:0006801,Rho GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin filament polymerization; cytosol; dendritic shaft; enzyme binding; growth cone; intracellular membrane-bounded organelle; intracellular signal transduction; neutrophil activation; perinuclear region of cytoplasm; phospholipid binding; plasma membrane; regulation of actin filament polymerization; regulation of dendrite development; superoxide metabolic process,PF00610;PF00621;,1.00E-55,CHOYP_VAV2.2.3,,,,,,,PREX1_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin filament polymerization [GO:0030833]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]; superoxide metabolic process [GO:0006801]; T cell differentiation [GO:0030217] comp134986_c1_seq57,2602,40.2767,0.49825525,0,0,,2.00E-17,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq58,2589,40.3631,0.49895164,0,0,,2.00E-17,Q13588,GRB2-related adapter protein,GRB2-related adapter protein,GO:0007265; GO:0005070; GO:0007267; GO:0005829,Ras protein signal transduction; SH3/SH2 adaptor activity; cell-cell signaling; cytosol,PF00017;PF00018;PF07653;,,,,,,,,,GRAP_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265] comp134986_c1_seq59,2957,41.9006,0.56222387,0,0,,1.00E-120,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,,,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq6,606,42.5743,0.73110708,0,0,,4.00E-09,Q8UUU2,Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),GO:0005943; GO:0043125; GO:0005158; GO:0008286; GO:0043560; GO:0005159; GO:0048009; GO:0035014; GO:0046854,"1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ErbB-3 class receptor binding; insulin receptor binding; insulin receptor signaling pathway; insulin receptor substrate binding; insulin-like growth factor receptor binding; insulin-like growth factor receptor signaling pathway; phosphatidylinositol 3-kinase regulator activity; phosphatidylinositol phosphorylation",PF16454;PF00620;PF00017;,,,,,,,,,P85AA_XENLA,Xenopus laevis (African clawed frog),cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] comp134986_c1_seq7,3107,40.972,0.5203793,0,0,,7.00E-117,P52735,Guanine nucleotide exchange factor VAV2 (VAV-2),Guanine nucleotide exchange factor VAV2 (VAV-2),GO:0038095; GO:0038096; GO:0005089; GO:0001525; GO:0097190; GO:0007411; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0030032; GO:0046872; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065; GO:0043552; GO:0035023; GO:0051056; GO:0007264,Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; Rho guanyl-nucleotide exchange factor activity; angiogenesis; apoptotic signaling pathway; axon guidance; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; lamellipodium assembly; metal ion binding; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;,3.00E-48,CHOYP_VAV2.1.3,,,,,,,VAV2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp134986_c1_seq8,2401,41.3161,0.55237448,0,0,,,,,,,,,3.00E-14,CHOYP_VAV2.2.3,,,,,,,,, comp134986_c1_seq9,1757,39.4422,0.62529449,0,0,,2.00E-08,P10686,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)",GO:0008180; GO:0005509; GO:0006816; GO:0071364; GO:0005737; GO:0032959; GO:0005158; GO:0035556; GO:0030027; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0010634; GO:0009306; GO:1901339; GO:0009629; GO:0042542; GO:0043278; GO:0001726; GO:0004871; GO:0007165,COP9 signalosome; calcium ion binding; calcium ion transport; cellular response to epidermal growth factor stimulus; cytoplasm; inositol trisphosphate biosynthetic process; insulin receptor binding; intracellular signal transduction; lamellipodium; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; positive regulation of epithelial cell migration; protein secretion; regulation of store-operated calcium channel activity; response to gravity; response to hydrogen peroxide; response to morphine; ruffle; signal transducer activity; signal transduction,PF00168;PF00388;PF00387;PF00017;PF00018;,,,,,,,,,PLCG1_RAT,Rattus norvegicus (Rat),activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; cellular response to epidermal growth factor stimulus [GO:0071364]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to gravity [GO:0009629]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165] comp134990_c0_seq1,1553,37.7334,0.48883317,125,65,,,,,,,,,3.00E-88,CHOYP_LOC100378309.1.1,,,,,,,,, comp134990_c0_seq3,672,36.4583,0.27764088,0,0,,,,,,,,,5.00E-12,CHOYP_LOC101164028.1.1,,,,,,,,, comp134993_c0_seq2,1591,41.6719,0.38102968,48,26,,2.00E-66,Q6DCF6,EF-hand calcium-binding domain-containing protein 7,EF-hand calcium-binding domain-containing protein 7,GO:0005509,calcium ion binding,PF13202;PF13499;,1.00E-42,CHOYP_EFCB7.1.1,,,,,,,EFCB7_XENLA,Xenopus laevis (African clawed frog), comp135003_c0_seq1,2378,41.7157,0.79691669,4,38,,2.00E-37,A8QL52,L-amino-acid oxidase (Bf-LAAO) (LAAO) (LAO) (EC 1.4.3.2),L-amino-acid oxidase (Bf-LAAO) (LAAO) (LAO) (EC 1.4.3.2),GO:0001716; GO:0006915; GO:0019835; GO:0042742; GO:0005576; GO:0044179,L-amino-acid oxidase activity; apoptotic process; cytolysis; defense response to bacterium; extracellular region; hemolysis in other organism,PF01593;,,,,,,,,,OXLA_BUNFA,Bungarus fasciatus (Banded krait) (Pseudoboa fasciata),apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179] comp135003_c0_seq3,2402,41.7569,0.78812109,0,0,,1.00E-38,O34363,Putative L-amino-acid oxidase YobN (EC 1.4.3.2),Putative L-amino-acid oxidase YobN (EC 1.4.3.2),GO:0001716,L-amino-acid oxidase activity,PF01593;,,,,,,,,,YOBN_BACSU,Bacillus subtilis (strain 168), comp135003_c0_seq4,2281,42.8759,0.77027926,0,0,,8.00E-40,B0VXW0,L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2),L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2),GO:0001716; GO:0006915; GO:0019835; GO:0042742; GO:0005576; GO:0044179,L-amino-acid oxidase activity; apoptotic process; cytolysis; defense response to bacterium; extracellular region; hemolysis in other organism,PF01593;,,,,,,,,,OXLA_SISCA,Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii),apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179] comp135005_c0_seq1,1611,39.4786,0.46305798,1288,1,male>female,1.00E-108,Q8C1W1,Vasohibin-1,Vasohibin-1,GO:0001525; GO:0045177; GO:0007050; GO:0005737; GO:0005783; GO:0005615; GO:0016525; GO:0043537; GO:0001937; GO:1901491; GO:0010628; GO:2000772; GO:0009611,angiogenesis; apical part of cell; cell cycle arrest; cytoplasm; endoplasmic reticulum; extracellular space; negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; negative regulation of endothelial cell proliferation; negative regulation of lymphangiogenesis; positive regulation of gene expression; regulation of cellular senescence; response to wounding,PF14822;,4.00E-74,CHOYP_VASH1.1.1,,,,,,,VASH1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell cycle arrest [GO:0007050]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of lymphangiogenesis [GO:1901491]; positive regulation of gene expression [GO:0010628]; regulation of cellular senescence [GO:2000772]; response to wounding [GO:0009611] comp135006_c0_seq1,2616,43.6544,0.4828112,247,540,,0,Q3ULF4,Paraplegin (EC 3.4.24.-),Paraplegin (EC 3.4.24.-),GO:0005524; GO:0008089; GO:0007155; GO:0016021; GO:0004222; GO:0031966; GO:0005739; GO:0007005; GO:0017111; GO:0006508; GO:0030155; GO:0008270,ATP binding; anterograde axon cargo transport; cell adhesion; integral to membrane; metalloendopeptidase activity; mitochondrial membrane; mitochondrion; mitochondrion organization; nucleoside-triphosphatase activity; proteolysis; regulation of cell adhesion; zinc ion binding,PF00004;PF06480;PF01434;,,,,,,,,,SPG7_MOUSE,Mus musculus (Mouse),anterograde axonal transport [GO:0008089]; cell adhesion [GO:0007155]; mitochondrion organization [GO:0007005]; nervous system development [GO:0007399]; proteolysis [GO:0006508]; regulation of cell adhesion [GO:0030155] comp135007_c1_seq1,2203,37.2674,0.47697608,0,0,,3.00E-14,O09032,ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),GO:0017091; GO:0000166,AU-rich element binding; nucleotide binding,PF00076;,4.00E-63,CHOYP_LOC659024.1.2,,,,,,,ELAV4_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; associative learning [GO:0008306]; cellular response to nerve growth factor stimulus [GO:1990090]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; positive regulation of dendrite development [GO:1900006]; regeneration [GO:0031099]; regulation of mRNA stability [GO:0043488]; response to cocaine [GO:0042220]; response to endoplasmic reticulum stress [GO:0034976] comp135007_c1_seq2,2265,37.8366,0.47431458,0,0,,2.00E-58,P52912,Nucleolysin TIA-1 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1),Nucleolysin TIA-1 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1),GO:0017091; GO:0006915; GO:0010494; GO:0042036; GO:0017148; GO:0000166; GO:0005634; GO:0048024,"AU-rich element binding; apoptotic process; cytoplasmic stress granule; negative regulation of cytokine biosynthetic process; negative regulation of translation; nucleotide binding; nucleus; regulation of mRNA splicing, via spliceosome",PF00076;,,,,,,,,,TIA1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp135007_c1_seq4,2716,39.0648,0.42727766,0,0,,2.00E-38,Q93W34,Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C),Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C),GO:0005829; GO:0006397; GO:0000166; GO:0005634; GO:0008143,cytosol; mRNA processing; nucleotide binding; nucleus; poly(A) RNA binding,PF00076;,,,,,,,,,RP45C_ARATH,Arabidopsis thaliana (Mouse-ear cress),mRNA processing [GO:0006397] comp135007_c1_seq5,2654,38.6209,0.42734951,0,0,,5.00E-111,P70318,Nucleolysin TIAR (TIA-1-related protein),Nucleolysin TIAR (TIA-1-related protein),GO:0017091; GO:0006915; GO:0010494; GO:0007281; GO:0000166; GO:0005634; GO:0008284; GO:0017145,AU-rich element binding; apoptotic process; cytoplasmic stress granule; germ cell development; nucleotide binding; nucleus; positive regulation of cell proliferation; stem cell division,PF00076;,5.00E-139,CHOYP_LOC659024.1.2,,,,,,,TIAR_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; germ cell development [GO:0007281]; positive regulation of cell proliferation [GO:0008284]; stem cell division [GO:0017145] comp135011_c0_seq1,1739,43.2432,0.37459378,0,0,,1.00E-89,Q8NFZ0,F-box only protein 18 (EC 3.6.4.12) (F-box DNA helicase 1),F-box DNA helicase 1 (hFBH1) (EC 3.6.4.12) (F-box only protein 18),GO:0005524; GO:0004003; GO:0003677; GO:0005634,ATP binding; ATP-dependent DNA helicase activity; DNA binding; nucleus,PF12937;PF00580;PF13361;,6.00E-85,CHOYP_FBXO18.2.2,,,,,,,FBX18_HUMAN,Homo sapiens (Human),"cell death [GO:0008219]; cellular response to DNA damage stimulus [GO:0006974]; DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of chromatin binding [GO:0035562]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of protein phosphorylation [GO:0001934]; protein ubiquitination [GO:0016567]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to intra-S DNA damage checkpoint signaling [GO:0072429]" comp135011_c0_seq2,2859,42.7772,0.40937478,0,0,,1.00E-159,Q8NFZ0,F-box only protein 18 (EC 3.6.4.12) (F-box DNA helicase 1),F-box DNA helicase 1 (hFBH1) (EC 3.6.4.12) (F-box only protein 18),GO:0005524; GO:0004003; GO:0003677; GO:0005634,ATP binding; ATP-dependent DNA helicase activity; DNA binding; nucleus,PF12937;PF00580;PF13361;,2.00E-87,CHOYP_FBXO18.2.2,,,,,,,FBX18_HUMAN,Homo sapiens (Human),"cell death [GO:0008219]; cellular response to DNA damage stimulus [GO:0006974]; DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of chromatin binding [GO:0035562]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of protein phosphorylation [GO:0001934]; protein ubiquitination [GO:0016567]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to intra-S DNA damage checkpoint signaling [GO:0072429]" comp135012_c0_seq1,685,45.5474,0.53637974,25,35,,3.00E-29,P40818,Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),GO:0007265; GO:0001669; GO:0008283; GO:0004197; GO:0005829; GO:0005769; GO:0010008; GO:0007032; GO:0019897; GO:0030496; GO:0000281; GO:0005634; GO:0071108; GO:0070536; GO:0004221; GO:0006511; GO:0004843,Ras protein signal transduction; acrosomal vesicle; cell proliferation; cysteine-type endopeptidase activity; cytosol; early endosome; endosome membrane; endosome organization; extrinsic to plasma membrane; midbody; mitotic cytokinesis; nucleus; protein K48-linked deubiquitination; protein K63-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00581;PF00443;PF08969;,5.00E-37,CHOYP_LOC100367006.2.2,,,,,,,UBP8_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; endosome organization [GO:0007032]; ERBB2 signaling pathway [GO:0038128]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent protein catabolic process [GO:0006511] comp135013_c0_seq1,1431,33.2635,0.55902787,2001,32761,,7.00E-39,Q07984,Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta),Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta),GO:0005784; GO:0016021,Sec61 translocon complex; integral to membrane,PF05404;,6.00E-27,CHOYP_PHUM_PHUM548270.1.1,,,,,,,SSRD_RAT,Rattus norvegicus (Rat), comp135016_c0_seq1,2117,37.0335,0.80383206,2,0,,4.00E-24,O08742,Platelet glycoprotein V (GPV) (Glycoprotein 5) (CD antigen CD42d),Platelet glycoprotein V (GPV) (Glycoprotein 5) (CD antigen CD42d),GO:0007596; GO:0007155; GO:0016021,blood coagulation; cell adhesion; integral to membrane,PF00560;PF13855;,,,,,,,,,GPV_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; blood coagulation [GO:0007596]; cell-matrix adhesion [GO:0007160]; negative regulation of platelet activation [GO:0010544] comp135016_c0_seq2,2136,36.6573,0.81360378,9,0,,1.00E-23,Q8R5M3,Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid) (rLib),Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid) (rLib),GO:0007154; GO:0016021; GO:0005622,cell communication; integral to membrane; intracellular,PF00560;PF13855;,,,,,,,,,LRC15_RAT,Rattus norvegicus (Rat),cell communication [GO:0007154]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469] comp135018_c0_seq1,649,41.2943,0.54375234,13,160,,2.00E-31,Q5VZY2,Phosphatidate phosphatase PPAPDC1A (EC 3.1.3.4) (Phosphatidic acid phosphatase type 2 domain-containing protein 1A),Phospholipid phosphatase 4 (EC 3.1.3.4) (Phosphatidic acid phosphatase type 2 domain-containing protein 1A),GO:0038096; GO:0045087; GO:0016021; GO:0008195; GO:0046839; GO:0005886,Fc-gamma receptor signaling pathway involved in phagocytosis; innate immune response; integral to membrane; phosphatidate phosphatase activity; phospholipid dephosphorylation; plasma membrane,PF01569;,,,,,,,,,PPC1A_HUMAN,Homo sapiens (Human),Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; signal transduction [GO:0007165] comp135018_c0_seq2,323,43.0341,0.47152219,0,7,,,,,,,,,3.00E-17,CHOYP_PPC1B.1.1,,,,,,,,, comp135018_c0_seq4,284,42.9577,0.62638139,0,10,,1.00E-11,Q9UUA6,Probable diacylglycerol pyrophosphate phosphatase 1 (DGPP phosphatase) (EC 3.1.3.81) (Phosphatidate phosphatase) (EC 3.1.3.4),Probable diacylglycerol pyrophosphate phosphatase 1 (DGPP phosphatase) (EC 3.1.3.81) (Phosphatidate phosphatase) (EC 3.1.3.4),GO:0000810; GO:0005783; GO:0005789; GO:0000329; GO:0016021; GO:0008195; GO:0006644; GO:0019932,diacylglycerol diphosphate phosphatase activity; endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole membrane; integral to membrane; phosphatidate phosphatase activity; phospholipid metabolic process; second-messenger-mediated signaling,PF01569;,,,,,,,,,DPP1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165] comp135019_c0_seq1,1247,34.9639,0.55714322,139,907,,2.00E-42,Q66KB9,Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2),Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2),GO:0031083; GO:0008089; GO:0048490; GO:0005813; GO:0031175; GO:0005634; GO:0045944,BLOC-1 complex; anterograde axon cargo transport; anterograde synaptic vesicle transport; centrosome; neuron projection development; nucleus; positive regulation of transcription from RNA polymerase II promoter,PF10046;,3.00E-31,CHOYP_BL1S2.1.1,1.00E-65,ruditapes_c12273,,,,,BL1S2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; neuron projection development [GO:0031175] comp135020_c0_seq1,1271,40.834,0.37880842,2,17,,4.00E-13,P22214,Protein transport protein SEC22 (Suppressor of loss of YPT1 protein 2),Protein transport protein SEC22 (Suppressor of loss of YPT1 protein 2),GO:0012507; GO:0006888; GO:0005794; GO:0000139; GO:0005484; GO:0031201; GO:0005783; GO:0005789; GO:0016021; GO:0015031; GO:0006890; GO:0048280; GO:0048279,"ER to Golgi transport vesicle membrane; ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi membrane; SNAP receptor activity; SNARE complex; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein transport; retrograde vesicle-mediated transport, Golgi to ER; vesicle fusion with Golgi apparatus; vesicle fusion with endoplasmic reticulum",PF13774;PF00957;,,,,,,,,,SEC22_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; vesicle fusion [GO:0006906]; vesicle fusion with endoplasmic reticulum [GO:0048279]; vesicle fusion with Golgi apparatus [GO:0048280]" comp135020_c0_seq2,1263,40.3009,0.37141997,0,11,,2.00E-64,Q8BH47,Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2),Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2),GO:0005789; GO:0016021; GO:0015031; GO:0016192,endoplasmic reticulum membrane; integral to membrane; protein transport; vesicle-mediated transport,PF13774;,,,,,,,,,SC22A_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; vesicle fusion with Golgi apparatus [GO:0048280] comp135021_c0_seq1,1313,41.3557,0.47298934,19,43,,2.00E-130,Q8NBK3,Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1),Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1),GO:0005788; GO:0006687; GO:0046872; GO:0016491; GO:0043687; GO:0044281,endoplasmic reticulum lumen; glycosphingolipid metabolic process; metal ion binding; oxidoreductase activity; post-translational protein modification; small molecule metabolic process,PF03781;,2.00E-108,CHOYP_LOC100568234.1.1,,,,,,,SUMF1_HUMAN,Homo sapiens (Human),glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687] comp135021_c0_seq2,978,43.2515,0.54424221,0,5,,1.00E-06,O69671,Iron(II)-dependent oxidoreductase EgtB (EC 1.8.-.-),Hercynine oxygenase (EC 1.14.99.50) (Gamma-glutamyl hercynylcysteine S-oxide synthase),GO:0052704; GO:0008198; GO:0016491,"ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine; ferrous iron binding; oxidoreductase activity",PF12867;PF03781;,,,,,,,,,EGTB_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),"ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine [GO:0052704]" comp135023_c1_seq1,2083,38.4542,0.56631164,16322,48569,,5.00E-167,Q8VEM8,"Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3)","Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3)",GO:0016021; GO:0005743; GO:0015293,integral to membrane; mitochondrial inner membrane; symporter activity,PF00153;,0,CHOYP_KIF2A.2.2,2.00E-166,ruditapes2_c3397,,,,,MPCP_MOUSE,Mus musculus (Mouse),translation [GO:0006412] comp135024_c0_seq1,1499,44.9633,0.59431694,30,13,,2.00E-85,Q7TMK9,"Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68)","Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68)",GO:0070937; GO:0070934; GO:0008380; GO:0071013; GO:0071346; GO:0071204; GO:0006397; GO:0017148; GO:0000166; GO:0008143,CRD-mediated mRNA stability complex; CRD-mediated mRNA stabilization; RNA splicing; catalytic step 2 spliceosome; cellular response to interferon-gamma; histone pre-mRNA 3'end processing complex; mRNA processing; negative regulation of translation; nucleotide binding; poly(A) RNA binding,PF00076;,,,,,,,,,HNRPQ_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380] comp135024_c0_seq2,1634,45.41,0.62214635,61,118,,2.00E-85,Q7TMK9,"Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68)","Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68)",GO:0070937; GO:0070934; GO:0008380; GO:0071013; GO:0071346; GO:0071204; GO:0006397; GO:0017148; GO:0000166; GO:0008143,CRD-mediated mRNA stability complex; CRD-mediated mRNA stabilization; RNA splicing; catalytic step 2 spliceosome; cellular response to interferon-gamma; histone pre-mRNA 3'end processing complex; mRNA processing; negative regulation of translation; nucleotide binding; poly(A) RNA binding,PF00076;,,,,,,,,,HNRPQ_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380] comp135026_c0_seq4,1147,41.4996,0.6844697,22,100,,1.00E-10,Q8TCT0,Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4),Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4),GO:0005524; GO:0003951; GO:0001729; GO:0006672; GO:0005737; GO:0004143; GO:0006687; GO:0016021; GO:0000287; GO:0005739; GO:0005634; GO:0005543; GO:0005886; GO:0007205; GO:0044281,ATP binding; NAD+ kinase activity; ceramide kinase activity; ceramide metabolic process; cytoplasm; diacylglycerol kinase activity; glycosphingolipid metabolic process; integral to membrane; magnesium ion binding; mitochondrion; nucleus; phospholipid binding; plasma membrane; protein kinase C-activating G-protein coupled receptor signaling pathway; small molecule metabolic process,PF00781;,,,,,,,,,CERK1_HUMAN,Homo sapiens (Human),ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687] comp135029_c0_seq2,1490,42.0134,0.55140557,7,3,,3.00E-72,Q96S15,WD repeat-containing protein 24,WD repeat-containing protein 24,,,PF00400;,9.00E-38,CHOYP_BRAFLDRAFT_60509.1.1,,,,,,,WDR24_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008] comp135029_c0_seq4,1558,43.5815,0.56069321,0,0,,1.00E-82,Q5ZMV9,WD repeat-containing protein 24,WD repeat-containing protein 24,,,PF00400;,,,,,,,,,WDR24_CHICK,Gallus gallus (Chicken),cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008] comp135036_c0_seq1,2064,41.5213,0.95774017,8622,49630,,1.00E-172,P53442,Fructose-bisphosphate aldolase (EC 4.1.2.13),Fructose-bisphosphate aldolase (EC 4.1.2.13),GO:0004332; GO:0006096,fructose-bisphosphate aldolase activity; glycolysis,PF00274;,7.00E-168,CHOYP_ALF.1.3,6.00E-52,ruditapes2_c703,,,,,ALF_SCHMA,Schistosoma mansoni (Blood fluke),glycolytic process [GO:0006096] comp135036_c1_seq1,786,34.4784,0.44848488,4749,33755,,7.00E-80,Q7ZTZ2,Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1),Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1),GO:0005730; GO:0042254,nucleolus; ribosome biogenesis,PF01246;,2.00E-99,CHOYP_RLP24.2.2,7.00E-129,ruditapes2_c200,,,,,RLP24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),assembly of large subunit precursor of preribosome [GO:1902626]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp135041_c0_seq1,2352,33.3333,1.21998736,199,729,,5.00E-55,A4II20,Early growth response protein 1 (EGR-1),Early growth response protein 1 (EGR-1),GO:0003677; GO:0071320; GO:0071371; GO:0005737; GO:0046872; GO:0043066; GO:0005634; GO:0048169; GO:0003700; GO:0035914; GO:0006351,"DNA binding; cellular response to cAMP; cellular response to gonadotropin stimulus; cytoplasm; metal ion binding; negative regulation of apoptotic process; nucleus; regulation of long-term neuronal synaptic plasticity; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription, DNA-dependent",PF11914;PF11928;,7.00E-67,CHOYP_EGR1.1.1,,,,,,,EGR1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135042_c0_seq4,1617,28.5714,0.5154703,1046,1271,,,,,,,,,,,2.00E-18,ruditapes_c5250,,,,,,, comp135046_c2_seq2,663,33.7858,0.48291019,22,66,,,,,,,,,,,2.00E-14,ruditapes2_c2720,,,,,,, comp135046_c2_seq9,338,32.5444,0.22782457,0,43,,,,,,,,,,,6.00E-11,ruditapes2_c1163,,,,,,, comp135050_c0_seq1,2192,42.2445,0.61069353,1,0,,2.00E-26,P15146,Microtubule-associated protein 2 (MAP-2),Microtubule-associated protein 2 (MAP-2),GO:0030425; GO:0005874; GO:0043025; GO:0043234; GO:0032355; GO:0032570; GO:0005791; GO:0005790,dendrite; microtubule; neuronal cell body; protein complex; response to estradiol stimulus; response to progesterone stimulus; rough endoplasmic reticulum; smooth endoplasmic reticulum,PF08377;PF00418;,,,,,,,,,MAP2_RAT,Rattus norvegicus (Rat),central nervous system neuron development [GO:0021954]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570] comp135050_c0_seq6,2152,41.5892,0.58898459,1,12,,5.00E-21,P57786,Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau),Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau),GO:0030424; GO:0005829; GO:0005874; GO:0005886,axon; cytosol; microtubule; plasma membrane,PF00418;,,,,,,,,,TAU_MACMU,Macaca mulatta (Rhesus macaque),microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175] comp135050_c0_seq7,217,40.553,0.72992622,2,0,,,,,,,,,2.00E-11,CHOYP_LOC100711676.1.1,,,,,,,,, comp135054_c0_seq1,1154,37.695,0.29343292,553,2106,,6.00E-58,Q28FE2,Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit soh1),Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit soh1),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF05669;,8.00E-63,CHOYP_MED31.1.1,,,,,,,MED31_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135056_c0_seq1,2181,41.6323,0.91986294,21,321,,7.00E-148,Q80Z96,Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1),Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1),GO:0016021; GO:0007275,integral to membrane; multicellular organismal development,PF06638;,2.00E-124,CHOYP_VANG.1.1,,,,,,,VANG1_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275] comp135057_c1_seq1,2032,41.437,0.95626153,4,150,,,,,,,,,3.00E-39,CHOYP_BRAFLDRAFT_86827.1.4,,,,,,,,, comp135057_c1_seq2,2021,41.5141,0.94594895,0,171,,,,,,,,,3.00E-39,CHOYP_BRAFLDRAFT_86827.1.4,,,,,,,,, comp135058_c1_seq2,354,43.5028,0.65963364,27,54,,3.00E-14,A2CG49,Kalirin (EC 2.7.11.1) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0005737; GO:0005856; GO:0046872; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; cytoskeleton; metal ion binding; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,2.00E-26,CHOYP_KALRN.2.2,,,,,,,KALRN_MOUSE,Mus musculus (Mouse),"behavioral fear response [GO:0001662]; behavioral response to cocaine [GO:0048148]; behavioral response to formalin induced pain [GO:0061368]; memory [GO:0007613]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of long-term synaptic potentiation [GO:1900273]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to mechanical stimulus [GO:0009612]; social behavior [GO:0035176]" comp135059_c1_seq1,702,36.6097,0.77055326,20,19,,3.00E-09,A4QN56,Sodium-dependent glucose transporter 1,Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B),GO:0016324; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,NAGT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp135060_c0_seq1,2346,39.5141,0.44482358,0,0,,2.00E-39,Q69VD9,Probable protein phosphatase 2C 57 (OsPP2C57) (EC 3.1.3.16),Probable protein phosphatase 2C 57 (OsPP2C57) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C57_ORYSJ,Oryza sativa subsp. japonica (Rice), comp135060_c0_seq2,2693,39.2128,0.52450388,0,0,,2.00E-163,P35815,Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta),Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta),GO:0006499; GO:0005829; GO:0000287; GO:0030145; GO:0016020; GO:0043124; GO:0042347; GO:0050687; GO:0032688; GO:0006470; GO:0004722,N-terminal protein myristoylation; cytosol; magnesium ion binding; manganese ion binding; membrane; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB import into nucleus; negative regulation of defense response to virus; negative regulation of interferon-beta production; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;PF07830;,4.00E-109,CHOYP_BRAFLDRAFT_275870.1.1,,,,,,,PPM1B_RAT,Rattus norvegicus (Rat),negative regulation of defense response to virus [GO:0050687]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; N-terminal protein myristoylation [GO:0006499]; protein dephosphorylation [GO:0006470] comp135060_c0_seq3,2312,39.4896,0.43984971,0,0,,6.00E-45,Q6ETK3,Probable protein phosphatase 2C 11 (OsPP2C11) (EC 3.1.3.16),Probable protein phosphatase 2C 11 (OsPP2C11) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C11_ORYSJ,Oryza sativa subsp. japonica (Rice), comp135060_c0_seq4,2659,39.1877,0.52095581,0,0,,2.00E-163,P35815,Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta),Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta),GO:0006499; GO:0005829; GO:0000287; GO:0030145; GO:0016020; GO:0043124; GO:0042347; GO:0050687; GO:0032688; GO:0006470; GO:0004722,N-terminal protein myristoylation; cytosol; magnesium ion binding; manganese ion binding; membrane; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB import into nucleus; negative regulation of defense response to virus; negative regulation of interferon-beta production; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;PF07830;,4.00E-109,CHOYP_BRAFLDRAFT_275870.1.1,,,,,,,PPM1B_RAT,Rattus norvegicus (Rat),negative regulation of defense response to virus [GO:0050687]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; N-terminal protein myristoylation [GO:0006499]; protein dephosphorylation [GO:0006470] comp135063_c1_seq2,1540,41.1688,0.75384647,0,0,,1.00E-42,Q9H3D4,Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51),Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51),GO:0006978; GO:0005794; GO:0007219; GO:0001077; GO:0007569; GO:0034644; GO:0003682; GO:0006338; GO:0060197; GO:0005829; GO:0003684; GO:0030425; GO:0003690; GO:0007499; GO:0030326; GO:0010481; GO:0002064; GO:0001736; GO:0048807; GO:0031069; GO:0042771; GO:0030216; GO:0043616; GO:0046872; GO:0031571; GO:0010259; GO:0043066; GO:0045617; GO:2000381; GO:0000122; GO:0051402; GO:0000790; GO:0005654; GO:0042475; GO:0002039; GO:0030859; GO:0045747; GO:2000271; GO:0002053; GO:0045669; GO:0045944; GO:0036342; GO:0060513; GO:0051289; GO:0009954; GO:0043523; GO:0010165; GO:0010332; GO:0043565; GO:0003700; GO:0001501; GO:0048745; GO:0060529; GO:0048485; GO:0005667; GO:0044212; GO:0060157,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; Golgi apparatus; Notch signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell aging; cellular response to UV; chromatin binding; chromatin remodeling; cloacal septation; cytosol; damaged DNA binding; dendrite; double-stranded DNA binding; ectoderm and mesoderm interaction; embryonic limb morphogenesis; epidermal cell division; epithelial cell development; establishment of planar polarity; female genitalia morphogenesis; hair follicle morphogenesis; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; keratinocyte differentiation; keratinocyte proliferation; metal ion binding; mitotic G1 DNA damage checkpoint; multicellular organismal aging; negative regulation of apoptotic process; negative regulation of keratinocyte differentiation; negative regulation of mesoderm development; negative regulation of transcription from RNA polymerase II promoter; neuron apoptotic process; nuclear chromatin; nucleoplasm; odontogenesis of dentin-containing tooth; p53 binding; polarized epithelial cell differentiation; positive regulation of Notch signaling pathway; positive regulation of fibroblast apoptotic process; positive regulation of mesenchymal cell proliferation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; prostatic bud formation; protein homotetramerization; proximal/distal pattern formation; regulation of neuron apoptotic process; response to X-ray; response to gamma radiation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal system development; smooth muscle tissue development; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; sympathetic nervous system development; transcription factor complex; transcription regulatory region DNA binding; urinary bladder development",PF00870;PF07710;PF07647;,8.00E-115,CHOYP_BRAFLDRAFT_67483.1.1,,,,,,,P63_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; ectoderm and mesoderm interaction [GO:0007499]; embryonic limb morphogenesis [GO:0030326]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G1 DNA damage checkpoint [GO:0031571]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of neuron apoptotic process [GO:0043523]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]; urinary bladder development [GO:0060157]" comp135063_c1_seq5,1155,46.9264,0.75235461,12,27,,1.00E-42,Q9JJP2,Tumor protein p73 (p53-like transcription factor) (p53-related protein),Tumor protein p73 (p53-like transcription factor) (p53-related protein),GO:0006978; GO:0007050; GO:0034644; GO:0033326; GO:0000785; GO:0003682; GO:0005829; GO:0003684; GO:0048546; GO:0003690; GO:0021766; GO:0006954; GO:0042771; GO:0046872; GO:0031571; GO:0043508; GO:0043524; GO:0000122; GO:0048666; GO:0005634; GO:0045793; GO:1902167; GO:0045944; GO:0009791; GO:0051262; GO:0001836; GO:0010165; GO:0010332; GO:0043565; GO:0003700; GO:0005667; GO:0044212; GO:0006351,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; cell cycle arrest; cellular response to UV; cerebrospinal fluid secretion; chromatin; chromatin binding; cytosol; damaged DNA binding; digestive tract morphogenesis; double-stranded DNA binding; hippocampus development; inflammatory response; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; metal ion binding; mitotic G1 DNA damage checkpoint; negative regulation of JUN kinase activity; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; neuron development; nucleus; positive regulation of cell size; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein tetramerization; release of cytochrome c from mitochondria; response to X-ray; response to gamma radiation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00870;PF07710;PF07647;,,,,,,,,,P73_MOUSE,Mus musculus (Mouse),"cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; cerebrospinal fluid secretion [GO:0033326]; digestive tract morphogenesis [GO:0048546]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; forebrain development [GO:0030900]; hippocampus development [GO:0021766]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cell size [GO:0045793]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902167]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein tetramerization [GO:0051262]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuron apoptotic process [GO:0043523]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]" comp135063_c1_seq6,1117,44.2256,0.73886883,0,0,,7.00E-44,Q9H3D4,Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51),Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51),GO:0006978; GO:0005794; GO:0007219; GO:0001077; GO:0007569; GO:0034644; GO:0003682; GO:0006338; GO:0060197; GO:0005829; GO:0003684; GO:0030425; GO:0003690; GO:0007499; GO:0030326; GO:0010481; GO:0002064; GO:0001736; GO:0048807; GO:0031069; GO:0042771; GO:0030216; GO:0043616; GO:0046872; GO:0031571; GO:0010259; GO:0043066; GO:0045617; GO:2000381; GO:0000122; GO:0051402; GO:0000790; GO:0005654; GO:0042475; GO:0002039; GO:0030859; GO:0045747; GO:2000271; GO:0002053; GO:0045669; GO:0045944; GO:0036342; GO:0060513; GO:0051289; GO:0009954; GO:0043523; GO:0010165; GO:0010332; GO:0043565; GO:0003700; GO:0001501; GO:0048745; GO:0060529; GO:0048485; GO:0005667; GO:0044212; GO:0060157,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; Golgi apparatus; Notch signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell aging; cellular response to UV; chromatin binding; chromatin remodeling; cloacal septation; cytosol; damaged DNA binding; dendrite; double-stranded DNA binding; ectoderm and mesoderm interaction; embryonic limb morphogenesis; epidermal cell division; epithelial cell development; establishment of planar polarity; female genitalia morphogenesis; hair follicle morphogenesis; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; keratinocyte differentiation; keratinocyte proliferation; metal ion binding; mitotic G1 DNA damage checkpoint; multicellular organismal aging; negative regulation of apoptotic process; negative regulation of keratinocyte differentiation; negative regulation of mesoderm development; negative regulation of transcription from RNA polymerase II promoter; neuron apoptotic process; nuclear chromatin; nucleoplasm; odontogenesis of dentin-containing tooth; p53 binding; polarized epithelial cell differentiation; positive regulation of Notch signaling pathway; positive regulation of fibroblast apoptotic process; positive regulation of mesenchymal cell proliferation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; prostatic bud formation; protein homotetramerization; proximal/distal pattern formation; regulation of neuron apoptotic process; response to X-ray; response to gamma radiation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal system development; smooth muscle tissue development; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; sympathetic nervous system development; transcription factor complex; transcription regulatory region DNA binding; urinary bladder development",PF00870;PF07710;PF07647;,6.00E-115,CHOYP_BRAFLDRAFT_67483.1.1,,,,,,,P63_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; ectoderm and mesoderm interaction [GO:0007499]; embryonic limb morphogenesis [GO:0030326]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G1 DNA damage checkpoint [GO:0031571]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of neuron apoptotic process [GO:0043523]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]; urinary bladder development [GO:0060157]" comp135065_c0_seq1,1278,41.3928,0.9521552,186,653,,9.00E-62,Q62633,"Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)","Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)",GO:0016324; GO:0008206; GO:0008508; GO:0016021; GO:0005634; GO:0000502,apical plasma membrane; bile acid metabolic process; bile acid:sodium symporter activity; integral to membrane; nucleus; proteasome complex,PF01758;,,,,,,,,,NTCP2_RAT,Rattus norvegicus (Rat),bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; sodium ion transport [GO:0006814] comp135065_c0_seq2,1128,32.8014,0.46973201,7,34,,5.00E-51,Q9UBF6,RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein),RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein),GO:0031466; GO:0019788; GO:0005507; GO:0005737; GO:0008631; GO:0043066; GO:0005634; GO:0045116; GO:0016567; GO:0051775; GO:0008270,Cul5-RING ubiquitin ligase complex; NEDD8 ligase activity; copper ion binding; cytoplasm; intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of apoptotic process; nucleus; protein neddylation; protein ubiquitination; response to redox state; zinc ion binding,PF12678;,,,,,,,,,RBX2_HUMAN,Homo sapiens (Human),protein neddylation [GO:0045116]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to redox state [GO:0051775]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp135065_c0_seq3,1106,33.1826,0.46861432,17,229,,5.00E-51,Q9UBF6,RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein),RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein),GO:0031466; GO:0019788; GO:0005507; GO:0005737; GO:0008631; GO:0043066; GO:0005634; GO:0045116; GO:0016567; GO:0051775; GO:0008270,Cul5-RING ubiquitin ligase complex; NEDD8 ligase activity; copper ion binding; cytoplasm; intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of apoptotic process; nucleus; protein neddylation; protein ubiquitination; response to redox state; zinc ion binding,PF12678;,4.00E-85,CHOYP_ISCW_ISCW016510.5.5,,,,,,,RBX2_HUMAN,Homo sapiens (Human),protein neddylation [GO:0045116]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to redox state [GO:0051775]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp135066_c2_seq1,1529,44.5389,0.69571527,116,195,,0,Q95ZJ1,Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),GO:0000139; GO:0016021; GO:0004653; GO:0018243,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation via threonine,PF00535;PF00652;,0,CHOYP_DMOJ_GI18492.1.1,,,,,,,GALT5_CAEEL,Caenorhabditis elegans,protein O-linked glycosylation via threonine [GO:0018243] comp135071_c0_seq3,2008,36.4044,0.44238344,15,60,,3.00E-33,Q9NWW6,Nicotinamide riboside kinase 1 (NRK 1) (NmR-K 1) (EC 2.7.1.22) (Nicotinic acid riboside kinase 1) (EC 2.7.1.173) (Ribosylnicotinamide kinase 1) (RNK 1) (Ribosylnicotinic acid kinase 1),Nicotinamide riboside kinase 1 (NRK 1) (NmR-K 1) (EC 2.7.1.22) (Nicotinic acid riboside kinase 1) (EC 2.7.1.173) (Ribosylnicotinamide kinase 1) (RNK 1) (Ribosylnicotinic acid kinase 1),GO:0005524; GO:0009435; GO:0006222; GO:0046872; GO:0050262; GO:0004849,ATP binding; NAD biosynthetic process; UMP biosynthetic process; metal ion binding; ribosylnicotinamide kinase activity; uridine kinase activity,,,,,,,,,,NRK1_HUMAN,Homo sapiens (Human),NAD biosynthetic process [GO:0009435] comp135072_c0_seq2,1705,42.0528,0.61346779,2,0,,0,Q7T2E3,Casein kinase I isoform delta-A (CKI-delta-A) (CKId-A) (EC 2.7.11.1) (Casein kinase I isoform delta-like),Casein kinase I isoform delta-A (CKI-delta-A) (CKId-A) (EC 2.7.11.1) (Casein kinase I isoform delta-like),GO:0005524; GO:0016055; GO:0005737; GO:0005634; GO:0004674,ATP binding; Wnt receptor signaling pathway; cytoplasm; nucleus; protein serine/threonine kinase activity,PF00069;,0,CHOYP_KC1D.3.3,,,,,,,KC1DA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055] comp135072_c0_seq4,1258,42.9253,0.68253702,6,5,,0,P49674,Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1),Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1),GO:0005524; GO:0006281; GO:0000086; GO:0034613; GO:0005829; GO:0030178; GO:0005634; GO:0090263; GO:0032436; GO:0004674; GO:0030529; GO:0007165,ATP binding; DNA repair; G2/M transition of mitotic cell cycle; cellular protein localization; cytosol; negative regulation of Wnt receptor signaling pathway; nucleus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein serine/threonine kinase activity; ribonucleoprotein complex; signal transduction,PF00069;,0,CHOYP_KC1D.3.3,4.00E-71,ruditapes_c16356,,,,,KC1E_HUMAN,Homo sapiens (Human),cellular protein localization [GO:0034613]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein binding [GO:0032091]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopaminergic neuron differentiation [GO:1904340]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cellular protein localization [GO:1903827]; regulation of circadian rhythm [GO:0042752]; rRNA processing [GO:0006364]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] comp135073_c0_seq1,1105,42.1719,0.49418245,60,537,,,,,,,,,1.00E-16,CHOYP_LOC100371142.1.1,,,,,,,,, comp135076_c0_seq2,2123,42.5341,0.89637865,256,34,,1.00E-24,Q80YR9,RNA-binding protein 12B-A (RNA-binding motif protein 12B-A),RNA-binding protein 12B-A (RNA-binding motif protein 12B-A),GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,,,,,,,,,R12BA_MOUSE,Mus musculus (Mouse), comp135078_c0_seq1,1990,39.799,0.46477981,5709,56,male>female,6.00E-113,Q6IND7,LRP2-binding protein,LRP2-binding protein,GO:0005737,cytoplasm,PF08238;,9.00E-84,CHOYP_LOC100371209.1.1,3.00E-56,ruditapes_c29727,,,,,LR2BP_XENLA,Xenopus laevis (African clawed frog), comp135082_c0_seq1,876,42.3516,0.48467195,26,90,,7.00E-78,Q5R8X9,Protein AMN1 homolog,Protein AMN1 homolog,,,PF13516;,2.00E-30,CHOYP_LOC752958.1.1,,,,,,,AMN1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp135090_c1_seq1,578,44.6367,0.71301242,6,49,,1.00E-33,Q7G191,Benzaldehyde dehydrogenase (NAD(+)) (EC 1.2.1.28) (Aldehyde oxidase 4) (AO-4) (AtAO-4) (AtAO2) (Indole-3-acetaldehyde oxidase) (IAA oxidase) (EC 1.2.3.7),Benzaldehyde dehydrogenase (NAD(+)) (EC 1.2.1.28) (Aldehyde oxidase 4) (AO-4) (AtAO-4) (AtAO2) (Indole-3-acetaldehyde oxidase) (IAA oxidase) (EC 1.2.3.7),GO:0051537; GO:0009688; GO:0018488; GO:0009851; GO:0018479; GO:0005829; GO:0009055; GO:0050660; GO:0019760; GO:0050302; GO:0005506; GO:0016614,"2 iron, 2 sulfur cluster binding; abscisic acid biosynthetic process; aryl-aldehyde oxidase activity; auxin biosynthetic process; benzaldehyde dehydrogenase (NAD+) activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; glucosinolate metabolic process; indole-3-acetaldehyde oxidase activity; iron ion binding; oxidoreductase activity, acting on CH-OH group of donors",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,ALDO4_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid biosynthetic process [GO:0009688]; auxin biosynthetic process [GO:0009851]; glucosinolate metabolic process [GO:0019760]; xanthine catabolic process [GO:0009115] comp135090_c2_seq1,649,41.2943,0.559478,0,0,,8.00E-71,Q9MYW6,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0009055; GO:0005576; GO:0050660; GO:0005506; GO:0043546; GO:0005777; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; extracellular region; flavin adenine dinucleotide binding; iron ion binding; molybdopterin cofactor binding; peroxisome; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_FELCA,Felis catus (Cat) (Felis silvestris catus),xanthine catabolic process [GO:0009115] comp135090_c2_seq2,945,43.5979,0.66145945,3,55,,2.00E-102,P80457,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0009055; GO:0005576; GO:0050660; GO:0005506; GO:0043546; GO:0005777; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; extracellular region; flavin adenine dinucleotide binding; iron ion binding; molybdopterin cofactor binding; peroxisome; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,4.00E-15,CHOYP_XDH.2.3,,,,,,,XDH_BOVIN,Bos taurus (Bovine),xanthine catabolic process [GO:0009115] comp135097_c0_seq1,668,42.3653,0.53573694,3,0,,,,,,,,,3.00E-34,CHOYP_LOC100378053.1.1,,,,,,,,, comp135097_c0_seq2,1790,37.933,0.623206,109,103,,1.00E-28,Q8NA66,Cyclic nucleotide-binding domain-containing protein 1,Cyclic nucleotide-binding domain-containing protein 1,,,,1.00E-43,CHOYP_LOC100378053.1.1,,,,,,,CNBD1_HUMAN,Homo sapiens (Human), comp135098_c0_seq1,2429,41.7867,0.48341052,13761,44242,,0,O18373,"Selenide, water dikinase (EC 2.7.9.3) (Protein patufet) (Selenium donor protein) (Selenophosphate synthase) (dSelD)","Selenide, water dikinase (EC 2.7.9.3) (Protein patufet) (Selenium donor protein) (Selenophosphate synthase) (dSelD)",GO:0005524; GO:0007049; GO:0008283; GO:0006541; GO:0007444; GO:0016301; GO:0007005; GO:2000378; GO:0022008; GO:0008284; GO:0016260,ATP binding; cell cycle; cell proliferation; glutamine metabolic process; imaginal disc development; kinase activity; mitochondrion organization; negative regulation of reactive oxygen species metabolic process; neurogenesis; positive regulation of cell proliferation; selenocysteine biosynthetic process,PF00586;PF02769;,0,CHOYP_HSP7D.3.3,4.00E-30,ruditapes2_c3605,,,,,SPS1_DROME,Drosophila melanogaster (Fruit fly),cell cycle [GO:0007049]; cell proliferation [GO:0008283]; glutamine metabolic process [GO:0006541]; imaginal disc development [GO:0007444]; mitochondrion organization [GO:0007005]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neurogenesis [GO:0022008]; positive regulation of cell proliferation [GO:0008284]; regulation of glucose metabolic process [GO:0010906]; selenocysteine biosynthetic process [GO:0016260] comp135100_c2_seq1,1015,45.8128,0.75239826,10,140,,1.00E-22,Q8NCT1,Arrestin domain-containing protein 4,Arrestin domain-containing protein 4,GO:0005768; GO:0005886; GO:0051443,endosome; plasma membrane; positive regulation of ubiquitin-protein ligase activity,PF02752;PF00339;,4.00E-15,CHOYP_TXNIP.1.1,2.00E-36,ruditapes_c13810,,,,,ARRD4_HUMAN,Homo sapiens (Human),positive regulation of ubiquitin-protein transferase activity [GO:0051443] comp135103_c0_seq10,699,40.3433,0.6213463,0,0,,,,,,,,,4.00E-19,CHOYP_RBM10.1.2,,,,,,,,, comp135103_c0_seq12,497,36.4185,0.67797304,0,0,,,,,,,,,9.00E-20,CHOYP_RBM10.2.2,,,,,,,,, comp135103_c0_seq16,470,44.0426,0.61848765,0,0,,,,,,,,,8.00E-20,CHOYP_RBM10.2.2,,,,,,,,, comp135103_c0_seq5,544,44.6691,0.63326285,0,0,,7.00E-30,Q99KG3,RNA-binding protein 10 (RNA-binding motif protein 10),RNA-binding protein 10 (RNA-binding motif protein 10),GO:0070935; GO:0003723; GO:0008285; GO:0000122; GO:0000166; GO:0005634; GO:0034393; GO:0008270,3'-UTR-mediated mRNA stabilization; RNA binding; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleotide binding; nucleus; positive regulation of smooth muscle cell apoptotic process; zinc ion binding,PF01585;PF00076;PF00641;,3.00E-19,CHOYP_RBM10.1.2,,,,,,,RBM10_MOUSE,Mus musculus (Mouse),"3'-UTR-mediated mRNA stabilization [GO:0070935]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of smooth muscle cell apoptotic process [GO:0034391]; RNA splicing [GO:0008380]" comp135106_c0_seq1,1644,42.8832,0.49352953,289,218,,6.00E-154,Q8BK67,Protein RCC2,Protein RCC2,GO:0051301; GO:0000775; GO:0005737; GO:0005874; GO:0007067; GO:0005730; GO:0005819,"cell division; chromosome, centromeric region; cytoplasm; microtubule; mitosis; nucleolus; spindle",PF00415;,3.00E-120,CHOYP_BRAFLDRAFT_67459.2.2,,,,,,,RCC2_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; cell division [GO:0051301]; chromosome passenger complex localization to kinetochore [GO:0072356]; establishment of protein localization [GO:0045184]; focal adhesion assembly [GO:0048041]; integrin-mediated signaling pathway [GO:0007229]; mitotic nuclear division [GO:0007067]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; regulation of cell migration [GO:0030334]; regulation of fibroblast migration [GO:0010762]; regulation of ruffle assembly [GO:1900027] comp135112_c0_seq1,2093,37.1715,1.17032303,4302,33402,,3.00E-77,Q2F637,14-3-3 protein zeta,14-3-3 protein zeta,GO:0005737,cytoplasm,PF00244;,5.00E-30,CHOYP_14332.2.2,3.00E-31,ruditapes_c8999,,,,,1433Z_BOMMO,Bombyx mori (Silk moth), comp135113_c0_seq1,2661,40.4735,0.48109667,1577,3540,,0,Q8R3N6,THO complex subunit 1 (Tho1) (Nuclear matrix protein p84),THO complex subunit 1 (Tho1) (Nuclear matrix protein p84),GO:0003677; GO:0003723; GO:0008380; GO:0000445; GO:0006915; GO:0005737; GO:0046784; GO:0006397; GO:0016363; GO:0016607; GO:0032784; GO:0007165; GO:0006351,"DNA binding; RNA binding; RNA splicing; THO complex part of transcription export complex; apoptotic process; cytoplasm; intronless viral mRNA export from host nucleus; mRNA processing; nuclear matrix; nuclear speck; regulation of DNA-dependent transcription, elongation; signal transduction; transcription, DNA-dependent",PF00531;PF11957;,3.00E-116,CHOYP_THOC1.1.1,,,,,,,THOC1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of isotype switching to IgA isotypes [GO:0048297]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; regulation of DNA-templated transcription, elongation [GO:0032784]; replication fork processing [GO:0031297]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; viral mRNA export from host cell nucleus [GO:0046784]" comp135114_c0_seq1,1683,42.1272,0.70166691,34,84556,female>male,1.00E-79,Q8N0N3,"Beta-1,3-glucan-binding protein (GBP)","Beta-1,3-glucan-binding protein (GBP)",GO:0001872; GO:0005975; GO:0005576; GO:0004553; GO:0045087,"(1->3)-beta-D-glucan binding; carbohydrate metabolic process; extracellular region; hydrolase activity, hydrolyzing O-glycosyl compounds; innate immune response",PF00722;,2.00E-16,CHOYP_LOC100889837.2.2,1.00E-73,ruditapes2_c1553,,,,,BGBP_PENMO,Penaeus monodon (Giant tiger prawn),carbohydrate metabolic process [GO:0005975]; innate immune response [GO:0045087] comp135117_c0_seq3,1194,39.2797,0.51936922,7,0,,9.00E-37,Q6ZTW0,Tubulin polyglutamylase complex subunit 1 (PGs1),Tubulin polyglutamylase complex subunit 1 (PGs1),GO:0030534; GO:0030424; GO:0005813; GO:0035085; GO:0030425; GO:0005874; GO:0005932; GO:0007275; GO:0018095; GO:0007288; GO:0007268; GO:0070740; GO:0051648,adult behavior; axon; centrosome; cilium axoneme; dendrite; microtubule; microtubule basal body; multicellular organismal development; protein polyglutamylation; sperm axoneme assembly; synaptic transmission; tubulin-glutamic acid ligase activity; vesicle localization,,4.00E-16,CHOYP_TYRO.1.1,,,,,,,TPGS1_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] comp135117_c0_seq4,1258,38.3148,0.517413,4,0,,3.00E-32,Q99MS8,Tubulin polyglutamylase complex subunit 1 (PGs1) (p32),Tubulin polyglutamylase complex subunit 1 (PGs1) (p32),GO:0030534; GO:0030424; GO:0005813; GO:0035085; GO:0030425; GO:0016021; GO:0005874; GO:0005932; GO:0008017; GO:0007275; GO:0018095; GO:0007288; GO:0007268; GO:0070740; GO:0051648,adult behavior; axon; centrosome; cilium axoneme; dendrite; integral to membrane; microtubule; microtubule basal body; microtubule binding; multicellular organismal development; protein polyglutamylation; sperm axoneme assembly; synaptic transmission; tubulin-glutamic acid ligase activity; vesicle localization,,1.00E-16,CHOYP_BRAFLDRAFT_121821.2.2,,,,,,,TPGS1_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] comp135117_c0_seq5,353,41.6431,0.745983,0,0,,7.00E-11,Q6ZTW0,Tubulin polyglutamylase complex subunit 1 (PGs1),Tubulin polyglutamylase complex subunit 1 (PGs1),GO:0030534; GO:0030424; GO:0005813; GO:0035085; GO:0030425; GO:0005874; GO:0005932; GO:0007275; GO:0018095; GO:0007288; GO:0007268; GO:0070740; GO:0051648,adult behavior; axon; centrosome; cilium axoneme; dendrite; microtubule; microtubule basal body; multicellular organismal development; protein polyglutamylation; sperm axoneme assembly; synaptic transmission; tubulin-glutamic acid ligase activity; vesicle localization,,,,,,,,,,TPGS1_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] comp135119_c0_seq1,1899,41.3375,0.9831992,55,706,,,,,,,,,1.00E-12,CHOYP_LOC100367844.1.1,,,,,,,,, comp135120_c0_seq11,303,37.2937,0.39200943,0,0,,1.00E-08,Q9MA55,Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4),Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4),GO:0005737; GO:0005829; GO:0000062; GO:0008289; GO:0006869; GO:0005634; GO:0009723; GO:0009753; GO:0009416; GO:0006810,cytoplasm; cytosol; fatty-acyl-CoA binding; lipid binding; lipid transport; nucleus; response to ethylene stimulus; response to jasmonic acid stimulus; response to light stimulus; transport,PF00887;,,,,,,,,,ACBP4_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to light stimulus [GO:0009416]; transport [GO:0006810] comp135120_c0_seq3,364,43.6813,0.3496195,0,0,,2.00E-26,Q80YG3,Kelch domain-containing protein 1,Kelch domain-containing protein 1,GO:0005737,cytoplasm,PF07646;,,,,,,,,,KLDC1_MOUSE,Mus musculus (Mouse), comp135121_c0_seq1,1505,45.0498,0.91783737,2260,21104,,2.00E-69,P28493,Pathogenesis-related protein 5 (PR-5),Pathogenesis-related protein 5 (PR-5),GO:0048046; GO:0005618; GO:0031540; GO:0010224; GO:0046686; GO:0009615; GO:0009627; GO:0005773,apoplast; cell wall; regulation of anthocyanin biosynthetic process; response to UV-B; response to cadmium ion; response to virus; systemic acquired resistance; vacuole,PF00314;,1.00E-54,CHOYP_ARALYDRAFT_472154.1.1,3.00E-17,ruditapes2_c3116,,,,,PR5_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of anthocyanin biosynthetic process [GO:0031540]; response to cadmium ion [GO:0046686]; response to UV-B [GO:0010224]; response to virus [GO:0009615]; systemic acquired resistance [GO:0009627] comp135122_c0_seq1,1603,38.1784,0.99508018,133,461,,3.00E-18,O61643,Inhibin beta chain (Activin beta chain) (dAct) (dActivin),Inhibin beta chain (Activin beta chain) (dAct) (dActivin),GO:0016049; GO:0048813; GO:0005576; GO:0005160,cell growth; dendrite morphogenesis; extracellular region; transforming growth factor beta receptor binding,PF00019;,,,,,,,,,INHB_DROME,Drosophila melanogaster (Fruit fly),cell development [GO:0048468]; cell growth [GO:0016049]; dendrite morphogenesis [GO:0048813]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395] comp135127_c2_seq1,469,41.5778,0.20008605,16,6,,9.00E-08,P03010,Putative AC9 transposase,Putative AC9 transposase,GO:0003677; GO:0006310; GO:0032196,DNA binding; DNA recombination; transposition,PF05699;PF14372;,,,,,,,,,TRAC9_MAIZE,Zea mays (Maize),DNA recombination [GO:0006310]; transposition [GO:0032196] comp135129_c0_seq1,2283,44.3714,0.67470177,6048,20243,,0,P14618,Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58),Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58),GO:0005524; GO:0005929; GO:0005829; GO:0070062; GO:0006096; GO:0000287; GO:0005739; GO:0005634; GO:0005886; GO:0030955; GO:0012501; GO:0004743; GO:0044281,ATP binding; cilium; cytosol; extracellular vesicular exosome; glycolysis; magnesium ion binding; mitochondrion; nucleus; plasma membrane; potassium ion binding; programmed cell death; pyruvate kinase activity; small molecule metabolic process,PF00224;PF02887;,0,CHOYP_KPYK.3.4,,,,,,,KPYM_HUMAN,Homo sapiens (Human),ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; liver development [GO:0001889]; organ regeneration [GO:0031100]; programmed cell death [GO:0012501]; pyruvate biosynthetic process [GO:0042866]; response to gravity [GO:0009629]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to muscle inactivity [GO:0014870]; response to nutrient [GO:0007584]; skeletal muscle tissue regeneration [GO:0043403] comp135132_c0_seq1,1533,39.2694,0.49593671,168,1022,,1.00E-76,Q9UBB5,Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2),Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2),GO:0043623; GO:0003682; GO:0005737; GO:0000792; GO:0000118; GO:0003729; GO:0042711; GO:0008327; GO:0000122; GO:0045892; GO:0005634; GO:0030177; GO:0042127; GO:0003696; GO:0035197; GO:0006351,"cellular protein complex assembly; chromatin binding; cytoplasm; heterochromatin; histone deacetylase complex; mRNA binding; maternal behavior; methyl-CpG binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of Wnt receptor signaling pathway; regulation of cell proliferation; satellite DNA binding; siRNA binding; transcription, DNA-dependent",PF01429;PF14048;PF16564;,1.00E-81,CHOYP_ISCW_ISCW010143.1.3,1.00E-66,ruditapes_c10269,,,,,MBD2_HUMAN,Homo sapiens (Human),"ATP-dependent chromatin remodeling [GO:0043044]; cellular protein complex assembly [GO:0043623]; chromatin silencing at rDNA [GO:0000183]; maternal behavior [GO:0042711]; methylation-dependent chromatin silencing [GO:0006346]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of cell proliferation [GO:0042127]; transcription, DNA-templated [GO:0006351]" comp135133_c0_seq1,2250,40.4889,0.47731138,68,551,,0,Q9Y3I0,tRNA-splicing ligase RtcB homolog (EC 6.5.1.3),tRNA-splicing ligase RtcB homolog (EC 6.5.1.3),GO:0005524; GO:0003972; GO:0007160; GO:0005737; GO:0001701; GO:0046872; GO:0001890; GO:0034446; GO:0006388; GO:0072669,"ATP binding; RNA ligase (ATP) activity; cell-matrix adhesion; cytoplasm; in utero embryonic development; metal ion binding; placenta development; substrate adhesion-dependent cell spreading; tRNA splicing, via endonucleolytic cleavage and ligation; tRNA-splicing ligase complex",PF01139;,0,CHOYP_RTCB.1.2,,,,,,,RTCB_HUMAN,Homo sapiens (Human),"in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp135134_c0_seq1,1421,42.1534,1.1816738,4,247,,2.00E-94,Q01460,Di-N-acetylchitobiase (EC 3.2.1.-),Di-N-acetylchitobiase (EC 3.2.1.-),GO:0006032; GO:0004568; GO:0005764; GO:0009313,chitin catabolic process; chitinase activity; lysosome; oligosaccharide catabolic process,PF00704;,,,,,,,,,DIAC_RAT,Rattus norvegicus (Rat),chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313] comp135134_c0_seq2,1042,43.2821,1.19685929,0,13,,8.00E-22,Q01458,Di-N-acetylchitobiase (EC 3.2.1.-) (Fragment),Di-N-acetylchitobiase (EC 3.2.1.-) (Fragment),GO:0005975; GO:0004553; GO:0005764,"carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; lysosome",,,,,,,,,,DIAC_BOVIN,Bos taurus (Bovine),carbohydrate metabolic process [GO:0005975] comp135136_c0_seq1,1440,40.2083,1.02580889,60,19,,7.00E-62,Q5XJQ7,Protein odd-skipped-related 1 (zOsr1),Protein odd-skipped-related 1 (zOsr1),GO:0035779; GO:0048389; GO:0048382; GO:0046872; GO:0000122; GO:0003676; GO:0005634; GO:0033339; GO:0035777; GO:0035775; GO:0035778; GO:0035776; GO:0006351,"angioblast cell differentiation; intermediate mesoderm development; mesendoderm development; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleic acid binding; nucleus; pectoral fin development; pronephric distal tubule development; pronephric glomerulus morphogenesis; pronephric nephron tubule epithelial cell differentiation; pronephric proximal tubule development; transcription, DNA-dependent",,9.00E-57,CHOYP_LOC100559685.1.1,,,,,,,OSR1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"angioblast cell differentiation [GO:0035779]; intermediate mesoderm development [GO:0048389]; kidney development [GO:0001822]; mesendoderm development [GO:0048382]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pectoral fin development [GO:0033339]; pronephric distal tubule development [GO:0035777]; pronephric glomerulus morphogenesis [GO:0035775]; pronephric nephron tubule epithelial cell differentiation [GO:0035778]; pronephric proximal tubule development [GO:0035776]; pronephros development [GO:0048793]; regulation of endodermal cell differentiation [GO:1903224]; regulation of nodal signaling pathway [GO:1900107]; transcription, DNA-templated [GO:0006351]" comp135143_c1_seq4,941,39.6387,0.409447,33,139,,1.00E-10,Q8TAM1,Bardet-Biedl syndrome 10 protein,Bardet-Biedl syndrome 10 protein,GO:0005524; GO:0044267; GO:0051131; GO:0005929; GO:0035058; GO:0045494; GO:0043254; GO:0050896; GO:0007601,ATP binding; cellular protein metabolic process; chaperone-mediated protein complex assembly; cilium; nonmotile primary cilium assembly; photoreceptor cell maintenance; regulation of protein complex assembly; response to stimulus; visual perception,PF00118;,,,,,,,,,BBS10_HUMAN,Homo sapiens (Human),chaperone-mediated protein complex assembly [GO:0051131]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; regulation of protein complex assembly [GO:0043254]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; visual perception [GO:0007601] comp135147_c1_seq1,760,45.3947,1.17762432,70,16,,3.00E-12,Q06441,Thrombospondin-4,Thrombospondin-4,GO:0005509; GO:0007155; GO:0031012; GO:0005615; GO:0051781; GO:0016529,calcium ion binding; cell adhesion; extracellular matrix; extracellular space; positive regulation of cell division; sarcoplasmic reticulum,PF11598;PF07645;PF02412;PF05735;,,,,,,,,,TSP4_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155]; positive regulation of cell division [GO:0051781]; response to unfolded protein [GO:0006986] comp135147_c1_seq2,961,51.3007,1.0490027,89,75,,6.00E-14,Q8N2S1,Latent-transforming growth factor beta-binding protein 4 (LTBP-4),Latent-transforming growth factor beta-binding protein 4 (LTBP-4),GO:0005509; GO:0030198; GO:0005615; GO:0005539; GO:0030252; GO:0005178; GO:0007275; GO:0006457; GO:0005578; GO:0045595; GO:0001558; GO:0030162; GO:0017015; GO:0050431; GO:0007179; GO:0005024,calcium ion binding; extracellular matrix organization; extracellular space; glycosaminoglycan binding; growth hormone secretion; integrin binding; multicellular organismal development; protein folding; proteinaceous extracellular matrix; regulation of cell differentiation; regulation of cell growth; regulation of proteolysis; regulation of transforming growth factor beta receptor signaling pathway; transforming growth factor beta binding; transforming growth factor beta receptor signaling pathway; transforming growth factor beta-activated receptor activity,PF07645;PF00683;,,,,,,,,,LTBP4_HUMAN,Homo sapiens (Human),growth hormone secretion [GO:0030252]; multicellular organism development [GO:0007275]; protein folding [GO:0006457]; regulation of cell differentiation [GO:0045595]; regulation of cell growth [GO:0001558]; regulation of proteolysis [GO:0030162]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] comp135147_c2_seq1,1973,42.7268,1.08411927,136,299,,4.00E-149,P35445,Cartilage oligomeric matrix protein (COMP),Cartilage oligomeric matrix protein (COMP),GO:0006915; GO:0005509; GO:0007155; GO:0008201; GO:0005578,apoptotic process; calcium ion binding; cell adhesion; heparin binding; proteinaceous extracellular matrix,PF11598;PF07645;PF02412;PF05735;,3.00E-103,CHOYP_PHUM_PHUM370970.1.2,,,,,,,COMP_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; cell adhesion [GO:0007155] comp135148_c0_seq2,1417,45.3776,0.88447113,17,14,,1.00E-08,O66990,Dihydroorotase (DHOase) (EC 3.5.2.3),Dihydroorotase (DHOase) (EC 3.5.2.3),GO:0044205; GO:0004151; GO:0008270,'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding,PF01979;,,,,,,,,,PYRC_AQUAE,Aquifex aeolicus (strain VF5),'de novo' UMP biosynthetic process [GO:0044205] comp135148_c0_seq3,1300,44.9231,0.85935413,0,11,,3.00E-12,Q9CGM7,Dihydroorotase (DHOase) (EC 3.5.2.3),Dihydroorotase (DHOase) (EC 3.5.2.3),GO:0044205; GO:0004151; GO:0008270,'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding,PF01979;,,,,,,,,,PYRC_LACLA,Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis),'de novo' UMP biosynthetic process [GO:0044205] comp135149_c0_seq1,937,41.0886,0.7246449,42,498,,3.00E-70,Q6AY62,Neuferricin (Cytochrome b5 domain-containing protein 2),Neuferricin (Cytochrome b5 domain-containing protein 2),GO:0005576; GO:0020037; GO:0007399,extracellular region; heme binding; nervous system development,PF00173;,,,,,,,,,NEUFC_RAT,Rattus norvegicus (Rat),positive regulation of neuron differentiation [GO:0045666] comp135151_c1_seq1,3157,42.477,0.35623241,0,0,,9.00E-51,Q8TDB6,E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),GO:0005737; GO:0006302; GO:0042393; GO:0010390; GO:0005634; GO:0004842; GO:0008270,cytoplasm; double-strand break repair; histone binding; histone monoubiquitination; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,DTX3L_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209] comp135151_c1_seq2,3093,41.9981,0.36354615,0,0,,8.00E-26,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135151_c1_seq3,2389,42.3608,0.31028343,0,0,,3.00E-51,Q8TDB6,E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),GO:0005737; GO:0006302; GO:0042393; GO:0010390; GO:0005634; GO:0004842; GO:0008270,cytoplasm; double-strand break repair; histone binding; histone monoubiquitination; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,DTX3L_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209] comp135154_c0_seq1,2058,38.484,0.54048582,4,8,,2.00E-17,Q567C3,UPF0739 protein C1orf74 homolog,UPF0739 protein C1orf74 homolog,,,PF14953;,,,,,,,,,CA074_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp135154_c0_seq3,2149,38.6226,0.51369475,31,160,,6.00E-27,Q5RB79,Ribonuclease P protein subunit p14 (EC 3.1.26.5),Ribonuclease P protein subunit p14 (EC 3.1.26.5),GO:0005634; GO:0004526; GO:0008033,nucleus; ribonuclease P activity; tRNA processing,PF01900;,,,,,,,,,RPP14_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),tRNA processing [GO:0008033] comp135157_c0_seq3,2221,40.6123,0.17567217,20,3,,8.00E-09,Q0VC16,Melanoma inhibitory activity protein 3 (Transport and Golgi organization protein 1),Melanoma inhibitory activity protein 3 (Transport and Golgi organization protein 1),GO:0005789; GO:0006887; GO:0016021; GO:0015031,endoplasmic reticulum membrane; exocytosis; integral to membrane; protein transport,PF07653;,,,,,,,,,MIA3_BOVIN,Bos taurus (Bovine),cargo loading into vesicle [GO:0035459]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; lipoprotein transport [GO:0042953]; protein transport [GO:0015031] comp135157_c0_seq5,1670,40.6587,0.20547375,0,0,,1.00E-09,Q5JRA6,Melanoma inhibitory activity protein 3 (C219-reactive peptide) (D320) (Transport and Golgi organization protein 1),Melanoma inhibitory activity protein 3 (C219-reactive peptide) (D320) (Transport and Golgi organization protein 1),GO:0005789; GO:0006887; GO:0016021; GO:0007162; GO:0030336; GO:0002687; GO:0015031; GO:0042060,endoplasmic reticulum membrane; exocytosis; integral to membrane; negative regulation of cell adhesion; negative regulation of cell migration; positive regulation of leukocyte migration; protein transport; wound healing,PF07653;,,,,,,,,,MIA3_HUMAN,Homo sapiens (Human),cargo loading into vesicle [GO:0035459]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; lipoprotein transport [GO:0042953]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; positive regulation of leukocyte migration [GO:0002687]; protein transport [GO:0015031]; wound healing [GO:0042060] comp135160_c0_seq1,1838,40.2067,0.59882792,76,316,,4.00E-115,P15019,Transaldolase (EC 2.2.1.2),Transaldolase (EC 2.2.1.2),GO:0005737; GO:0005634; GO:0006098; GO:0004801,cytoplasm; nucleus; pentose-phosphate shunt; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity,PF00923;,,,,,,,,,TAL1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098] comp135160_c0_seq2,1695,40.472,0.60896125,86,367,,3.00E-149,Q93092,Transaldolase (EC 2.2.1.2),Transaldolase (EC 2.2.1.2),GO:0005737; GO:0006098; GO:0004801,cytoplasm; pentose-phosphate shunt; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity,PF00923;,4.00E-100,CHOYP_TALDO.2.2,,,,,,,TALDO_MOUSE,Mus musculus (Mouse),"carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]" comp135161_c0_seq1,3110,42.8617,0.38522763,183,419,,0,P27398,Calpain-D (EC 3.4.22.-) (Calcium-activated neutral proteinase D) (CANP D) (Small optic lobes protein),Calpain-D (EC 3.4.22.-) (Calcium-activated neutral proteinase D) (CANP D) (Small optic lobes protein),GO:0004198; GO:0005737; GO:0007399; GO:0006508; GO:0050896; GO:0007601; GO:0008270,calcium-dependent cysteine-type endopeptidase activity; cytoplasm; nervous system development; proteolysis; response to stimulus; visual perception; zinc ion binding,PF00648;PF00641;,2.00E-131,CHOYP_LOC101159619.1.1,,,,,,,CAND_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; proteolysis [GO:0006508]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp135165_c0_seq1,1093,36.4135,0.77920293,0,27,,1.00E-29,Q9BSG1,Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661),Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZNF2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135165_c0_seq2,1049,36.4156,0.84489533,3,8,,1.00E-29,Q9BSG1,Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661),Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZNF2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135166_c0_seq1,2035,45.4545,0.95495417,108,729,,7.00E-112,Q5RBP9,Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1),Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1),GO:0016021,integral to membrane,PF01823;,,,,,,,,,MPEG1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp135168_c0_seq1,541,42.5139,0.69930415,9,145,,1.00E-07,Q895K2,DNA polymerase III PolC-type (PolIII) (EC 2.7.7.7),DNA polymerase III PolC-type (PolIII) (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0006260; GO:0003887; GO:0005737; GO:0090305,3'-5' exonuclease activity; DNA binding; DNA replication; DNA-directed DNA polymerase activity; cytoplasm; nucleic acid phosphodiester bond hydrolysis,PF11490;PF07733;PF14579;PF02811;PF00929;PF01336;,,,,,,,,,DPO3_CLOTE,Clostridium tetani (strain Massachusetts / E88),DNA-dependent DNA replication [GO:0006261] comp135170_c0_seq1,1648,35.4976,0.25179722,652,2442,,1.00E-72,O75832,26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK)),26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK)),GO:0006977; GO:0000082; GO:0015629; GO:0031145; GO:0002479; GO:0006915; GO:0007253; GO:0005829; GO:0010467; GO:0045111; GO:0016071; GO:0043518; GO:0043409; GO:0032088; GO:0043066; GO:0090201; GO:0000122; GO:0051436; GO:0005654; GO:0030307; GO:0045737; GO:0032436; GO:0051437; GO:0005838; GO:0070682; GO:0000209; GO:0006521; GO:0044281; GO:0016032,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; G1/S transition of mitotic cell cycle; actin cytoskeleton; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; apoptotic process; cytoplasmic sequestering of NF-kappaB; cytosol; gene expression; intermediate filament cytoskeleton; mRNA metabolic process; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of MAPK cascade; negative regulation of NF-kappaB transcription factor activity; negative regulation of apoptotic process; negative regulation of release of cytochrome c from mitochondria; negative regulation of transcription from RNA polymerase II promoter; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of cell growth; positive regulation of cyclin-dependent protein kinase activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; proteasome regulatory particle; proteasome regulatory particle assembly; protein polyubiquitination; regulation of cellular amino acid metabolic process; small molecule metabolic process; viral process",PF00023;PF12796;,2.00E-52,CHOYP_LOC100371457.1.1,,,,,,,PSD10_HUMAN,Homo sapiens (Human),"anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteasome regulatory particle assembly [GO:0070682]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp135174_c0_seq1,1190,39.8319,0.25665817,37,140,,2.00E-44,Q5XIT9,"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)","Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)",GO:0005524; GO:0015936; GO:0006552; GO:0004485; GO:0005759,ATP binding; coenzyme A metabolic process; leucine catabolic process; methylcrotonoyl-CoA carboxylase activity; mitochondrial matrix,PF01039;,,,,,,,,,MCCB_RAT,Rattus norvegicus (Rat),coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552] comp135175_c1_seq3,1552,41.1727,0.36805324,150,877,,2.00E-64,Q1NZ26,"Uncharacterized protein F13E9.13, mitochondrial","Uncharacterized protein F13E9.13, mitochondrial",GO:0003824; GO:0005739,catalytic activity; mitochondrion,PF03437;,,,,,,,,,YSMU_CAEEL,Caenorhabditis elegans,metabolic process [GO:0008152] comp135177_c0_seq1,244,44.6721,0.99662691,0,32,,7.00E-13,Q95332,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (Fragment),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (Fragment),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,,,,,,,,,BHMT1_PIG,Sus scrofa (Pig),amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086] comp135177_c1_seq1,1032,40.1163,0.8606702,3,208,,1.00E-16,Q5RF32,S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2),S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2),GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,8.00E-18,CHOYP_LOC100371248.2.2,,,,,,,BHMT2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),methionine biosynthetic process [GO:0009086] comp135181_c0_seq1,1252,42.9712,0.75527474,0,0,,1.00E-68,Q6CFI3,DNA damage-inducible protein 1,DNA damage-inducible protein 1,GO:0004190; GO:0005737; GO:0015031; GO:0006508,aspartic-type endopeptidase activity; cytoplasm; protein transport; proteolysis,PF09668;PF00627;,,,,,,,,,DDI1_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),protein transport [GO:0015031] comp135181_c0_seq2,1859,40.2905,0.76627322,4,15,,1.00E-129,Q5TDH0,Protein DDI1 homolog 2,Protein DDI1 homolog 2,GO:0004190; GO:0006508,aspartic-type endopeptidase activity; proteolysis,PF09668;PF00240;,,,,,,,,,DDI2_HUMAN,Homo sapiens (Human), comp135181_c0_seq4,1843,40.2604,0.77355278,13,0,,2.00E-112,Q8WTU0,Protein DDI1 homolog 1,Protein DDI1 homolog 1,GO:0004190; GO:0006508,aspartic-type endopeptidase activity; proteolysis,PF09668;PF00240;,,,,,,,,,DDI1_HUMAN,Homo sapiens (Human), comp135181_c0_seq5,1872,40.2244,0.74995016,3,3,,3.00E-106,A0JPP7,Protein DDI1 homolog 1,Protein DDI1 homolog 1,GO:0004190; GO:0006508,aspartic-type endopeptidase activity; proteolysis,PF09668;PF00240;,4.00E-69,CHOYP_LOC658280.1.1,,,,,,,DDI1_RAT,Rattus norvegicus (Rat), comp135183_c0_seq1,1278,39.6714,0.86502468,24,1019,,2.00E-20,Q8N6F8,Williams-Beuren syndrome chromosomal region 27 protein,Williams-Beuren syndrome chromosomal region 27 protein,,,,7.00E-13,CHOYP_BRAFLDRAFT_121459.1.1,,,,,,,WBS27_HUMAN,Homo sapiens (Human),methylation [GO:0032259] comp135184_c0_seq9,760,31.8421,0.36386675,0,0,,,,,,,,,,,8.00E-14,ruditapes_c14315,,,,,,, comp135185_c3_seq1,1652,41.3438,0.50389337,10,22,,3.00E-44,Q3V124,EP300-interacting inhibitor of differentiation 3 (EID-3) (EID-1-like inhibitor of differentiation 3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B),EP300-interacting inhibitor of differentiation 3 (EID-3) (EID-1-like inhibitor of differentiation 3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B),GO:0006310; GO:0006281; GO:0030915; GO:0000781; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"DNA recombination; DNA repair; Smc5-Smc6 complex; chromosome, telomeric region; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15412;PF08743;,,,,,,,,,EID3_MOUSE,Mus musculus (Mouse),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135185_c3_seq2,1628,41.4005,0.50920363,2,8,,4.00E-08,P43124,Non-structural maintenance of chromosome element 4 (Non-SMC element 4) (Protein QRI2),Non-structural maintenance of chromosome element 4 (Non-SMC element 4) (Protein QRI2),GO:0006310; GO:0006281; GO:0030915; GO:0005634,DNA recombination; DNA repair; Smc5-Smc6 complex; nucleus,PF15412;PF08743;,,,,,,,,,NSE4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; protein sumoylation [GO:0016925] comp135186_c0_seq1,1465,32.1502,0.47581976,1328,4782,,9.00E-57,P52435,DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit),DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit),GO:0006370; GO:0003677; GO:0005665; GO:0003899; GO:0000398; GO:0050434; GO:0006368; GO:0006367; GO:0006283; GO:0016032,"7-methylguanosine mRNA capping; DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; mRNA splicing, via spliceosome; positive regulation of viral transcription; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; viral process",,2.00E-66,CHOYP_ISCW_ISCW008174.1.2,9.00E-80,ruditapes_c18745,,,,,RPB11_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral transcription [GO:0050434]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp135188_c3_seq1,864,40.8565,0.75714943,343,2850,,1.00E-51,P11064,Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2),Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2),GO:0003993; GO:0005737; GO:0004726; GO:0035335,acid phosphatase activity; cytoplasm; non-membrane spanning protein tyrosine phosphatase activity; peptidyl-tyrosine dephosphorylation,PF01451;,,,,,,,,,PPAC_BOVIN,Bos taurus (Bovine), comp135194_c0_seq1,363,41.8733,0.39140082,0,5,,,,,,,,,1.00E-41,CHOYP_MYO1E.1.1,,,,,,,,, comp135194_c1_seq10,2288,44.493,0.62919442,0,0,,0,Q02440,"Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain p190) (Myosin-V)","Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain p190) (Myosin-V)",GO:0005524; GO:0000139; GO:0032869; GO:0031941; GO:0032593; GO:0060001; GO:0016459; GO:0072659; GO:0016192,ATP binding; Golgi membrane; cellular response to insulin stimulus; filamentous actin; insulin-responsive compartment; minus-end directed microfilament motor activity; myosin complex; protein localization to plasma membrane; vesicle-mediated transport,PF01843;PF00612;PF00063;,1.00E-177,CHOYP_MYO5A.3.4,,,,,,,MYO5A_CHICK,Gallus gallus (Chicken),cellular response to insulin stimulus [GO:0032869]; protein localization to plasma membrane [GO:0072659]; vesicle-mediated transport [GO:0016192] comp135194_c1_seq11,2312,44.4204,0.63353,0,0,,3.00E-08,P55196,Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),GO:0034332; GO:0045177; GO:0007155; GO:0034329; GO:0005913; GO:0005911; GO:0007267; GO:0005829; GO:0005634; GO:0005886; GO:0008022; GO:0007165,adherens junction organization; apical part of cell; cell adhesion; cell junction assembly; cell-cell adherens junction; cell-cell junction; cell-cell signaling; cytosol; nucleus; plasma membrane; protein C-terminus binding; signal transduction,PF01843;PF00498;PF00595;PF00788;,2.00E-176,CHOYP_MYO5A.1.4,,,,,,,AFAD_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp135194_c1_seq12,3885,45.1737,0.65066928,0,0,,2.00E-23,Q63358,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0043531; GO:0005524; GO:0043008; GO:0005100; GO:0007266; GO:0005884; GO:0051015; GO:0030898; GO:0005938; GO:0030027; GO:0003774; GO:0016459; GO:0048471; GO:0001726; GO:0008270,ADP binding; ATP binding; ATP-dependent protein binding; Rho GTPase activator activity; Rho protein signal transduction; actin filament; actin filament binding; actin-dependent ATPase activity; cell cortex; lamellipodium; motor activity; myosin complex; perinuclear region of cytoplasm; ruffle; zinc ion binding,PF00612;PF00063;PF00788;PF00620;,2.00E-177,CHOYP_MYO5A.3.4,,,,,,,MYO9B_RAT,Rattus norvegicus (Rat),actin filament-based movement [GO:0030048]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp135194_c1_seq13,4135,45.2479,0.62214203,0,0,,0,P70569,Unconventional myosin-Vb (Myosin heavy chain myr 6),Unconventional myosin-Vb (Myosin heavy chain myr 6),GO:0005524; GO:0017137; GO:0043197; GO:0003774; GO:0016459; GO:0043025; GO:0048471; GO:0015031; GO:0032880,ATP binding; Rab GTPase binding; dendritic spine; motor activity; myosin complex; neuronal cell body; perinuclear region of cytoplasm; protein transport; regulation of protein localization,PF01843;PF00612;PF00063;,1.00E-16,CHOYP_MYO1E.1.1,,,,,,,MYO5B_RAT,Rattus norvegicus (Rat),endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880] comp135194_c1_seq15,3422,43.8925,0.61721054,0,0,,0,Q9Y4I1,"Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)","Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)",GO:0005524; GO:0005794; GO:0030048; GO:0042641; GO:0042640; GO:0005509; GO:0044267; GO:0032869; GO:0051643; GO:0006887; GO:0030426; GO:0030073; GO:0032593; GO:0005882; GO:0031987; GO:0042759; GO:0042438; GO:0030318; GO:0042470; GO:0032402; GO:0000146; GO:0035371; GO:0042552; GO:0016459; GO:0043025; GO:0042476; GO:0001750; GO:0072659; GO:0031585; GO:0001726; GO:0032252; GO:0050808; GO:0007268; GO:0016192; GO:0007601,"ATP binding; Golgi apparatus; actin filament-based movement; actomyosin; anagen; calcium ion binding; cellular protein metabolic process; cellular response to insulin stimulus; endoplasmic reticulum localization; exocytosis; growth cone; insulin secretion; insulin-responsive compartment; intermediate filament; locomotion involved in locomotory behavior; long-chain fatty acid biosynthetic process; melanin biosynthetic process; melanocyte differentiation; melanosome; melanosome transport; microfilament motor activity; microtubule plus end; myelination; myosin complex; neuronal cell body; odontogenesis; photoreceptor outer segment; protein localization to plasma membrane; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ruffle; secretory granule localization; synapse organization; synaptic transmission; vesicle-mediated transport; visual perception",PF01843;PF00612;PF00063;,9.00E-17,CHOYP_MYO1E.1.1,,,,,,,MYO5A_HUMAN,Homo sapiens (Human),"actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; myelination [GO:0042552]; odontogenesis [GO:0042476]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; transport [GO:0006810]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]" comp135194_c1_seq16,3909,45.1266,0.65310201,0,0,,2.00E-23,Q63358,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0043531; GO:0005524; GO:0043008; GO:0005100; GO:0007266; GO:0005884; GO:0051015; GO:0030898; GO:0005938; GO:0030027; GO:0003774; GO:0016459; GO:0048471; GO:0001726; GO:0008270,ADP binding; ATP binding; ATP-dependent protein binding; Rho GTPase activator activity; Rho protein signal transduction; actin filament; actin filament binding; actin-dependent ATPase activity; cell cortex; lamellipodium; motor activity; myosin complex; perinuclear region of cytoplasm; ruffle; zinc ion binding,PF00612;PF00063;PF00788;PF00620;,3.00E-176,CHOYP_MYO5A.3.4,,,,,,,MYO9B_RAT,Rattus norvegicus (Rat),actin filament-based movement [GO:0030048]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp135194_c1_seq17,4111,45.2931,0.6197221,0,0,,0,P70569,Unconventional myosin-Vb (Myosin heavy chain myr 6),Unconventional myosin-Vb (Myosin heavy chain myr 6),GO:0005524; GO:0017137; GO:0043197; GO:0003774; GO:0016459; GO:0043025; GO:0048471; GO:0015031; GO:0032880,ATP binding; Rab GTPase binding; dendritic spine; motor activity; myosin complex; neuronal cell body; perinuclear region of cytoplasm; protein transport; regulation of protein localization,PF01843;PF00612;PF00063;,,,,,,,,,MYO5B_RAT,Rattus norvegicus (Rat),endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880] comp135194_c1_seq19,4773,44.6679,0.61077885,0,0,,0,P70569,Unconventional myosin-Vb (Myosin heavy chain myr 6),Unconventional myosin-Vb (Myosin heavy chain myr 6),GO:0005524; GO:0017137; GO:0043197; GO:0003774; GO:0016459; GO:0043025; GO:0048471; GO:0015031; GO:0032880,ATP binding; Rab GTPase binding; dendritic spine; motor activity; myosin complex; neuronal cell body; perinuclear region of cytoplasm; protein transport; regulation of protein localization,PF01843;PF00612;PF00063;,3.00E-177,CHOYP_MYO5A.3.4,,,,,,,MYO5B_RAT,Rattus norvegicus (Rat),endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880] comp135194_c1_seq2,3398,43.9376,0.614109,0,0,,0,Q9Y4I1,"Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)","Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)",GO:0005524; GO:0005794; GO:0030048; GO:0042641; GO:0042640; GO:0005509; GO:0044267; GO:0032869; GO:0051643; GO:0006887; GO:0030426; GO:0030073; GO:0032593; GO:0005882; GO:0031987; GO:0042759; GO:0042438; GO:0030318; GO:0042470; GO:0032402; GO:0000146; GO:0035371; GO:0042552; GO:0016459; GO:0043025; GO:0042476; GO:0001750; GO:0072659; GO:0031585; GO:0001726; GO:0032252; GO:0050808; GO:0007268; GO:0016192; GO:0007601,"ATP binding; Golgi apparatus; actin filament-based movement; actomyosin; anagen; calcium ion binding; cellular protein metabolic process; cellular response to insulin stimulus; endoplasmic reticulum localization; exocytosis; growth cone; insulin secretion; insulin-responsive compartment; intermediate filament; locomotion involved in locomotory behavior; long-chain fatty acid biosynthetic process; melanin biosynthetic process; melanocyte differentiation; melanosome; melanosome transport; microfilament motor activity; microtubule plus end; myelination; myosin complex; neuronal cell body; odontogenesis; photoreceptor outer segment; protein localization to plasma membrane; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ruffle; secretory granule localization; synapse organization; synaptic transmission; vesicle-mediated transport; visual perception",PF01843;PF00612;PF00063;,9.00E-17,CHOYP_MYO1E.1.1,,,,,,,MYO5A_HUMAN,Homo sapiens (Human),"actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; myelination [GO:0042552]; odontogenesis [GO:0042476]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; transport [GO:0006810]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]" comp135194_c1_seq20,2534,44.3962,0.68282839,0,0,,2.00E-23,Q9QY06,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0005524; GO:0005096; GO:0005100; GO:0007266; GO:0005938; GO:0030010; GO:0032433; GO:0035556; GO:0030027; GO:0072673; GO:0048246; GO:0046872; GO:0000146; GO:0002548; GO:0016459; GO:0048471; GO:0043547; GO:0001726,ATP binding; GTPase activator activity; Rho GTPase activator activity; Rho protein signal transduction; cell cortex; establishment of cell polarity; filopodium tip; intracellular signal transduction; lamellipodium; lamellipodium morphogenesis; macrophage chemotaxis; metal ion binding; microfilament motor activity; monocyte chemotaxis; myosin complex; perinuclear region of cytoplasm; positive regulation of GTPase activity; ruffle,PF00612;PF00063;PF00788;PF00620;,,,,,,,,,MYO9B_MOUSE,Mus musculus (Mouse),actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp135194_c1_seq21,2510,44.4622,0.67914634,0,0,,9.00E-24,Q63358,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0043531; GO:0005524; GO:0043008; GO:0005100; GO:0007266; GO:0005884; GO:0051015; GO:0030898; GO:0005938; GO:0030027; GO:0003774; GO:0016459; GO:0048471; GO:0001726; GO:0008270,ADP binding; ATP binding; ATP-dependent protein binding; Rho GTPase activator activity; Rho protein signal transduction; actin filament; actin filament binding; actin-dependent ATPase activity; cell cortex; lamellipodium; motor activity; myosin complex; perinuclear region of cytoplasm; ruffle; zinc ion binding,PF00612;PF00063;PF00788;PF00620;,,,,,,,,,MYO9B_RAT,Rattus norvegicus (Rat),actin filament-based movement [GO:0030048]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp135194_c1_seq22,1323,44.0665,0.54536927,0,0,,4.00E-129,Q9NQX4,Unconventional myosin-Vc,Unconventional myosin-Vc,GO:0005524; GO:0003774; GO:0016459,ATP binding; motor activity; myosin complex,PF01843;PF00612;PF00063;,1.00E-149,CHOYP_MYO5A.1.4,,,,,,,MYO5C_HUMAN,Homo sapiens (Human), comp135194_c1_seq26,1697,43.9599,0.61121371,0,0,,9.00E-175,Q9Y4I1,"Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)","Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)",GO:0005524; GO:0005794; GO:0030048; GO:0042641; GO:0042640; GO:0005509; GO:0044267; GO:0032869; GO:0051643; GO:0006887; GO:0030426; GO:0030073; GO:0032593; GO:0005882; GO:0031987; GO:0042759; GO:0042438; GO:0030318; GO:0042470; GO:0032402; GO:0000146; GO:0035371; GO:0042552; GO:0016459; GO:0043025; GO:0042476; GO:0001750; GO:0072659; GO:0031585; GO:0001726; GO:0032252; GO:0050808; GO:0007268; GO:0016192; GO:0007601,"ATP binding; Golgi apparatus; actin filament-based movement; actomyosin; anagen; calcium ion binding; cellular protein metabolic process; cellular response to insulin stimulus; endoplasmic reticulum localization; exocytosis; growth cone; insulin secretion; insulin-responsive compartment; intermediate filament; locomotion involved in locomotory behavior; long-chain fatty acid biosynthetic process; melanin biosynthetic process; melanocyte differentiation; melanosome; melanosome transport; microfilament motor activity; microtubule plus end; myelination; myosin complex; neuronal cell body; odontogenesis; photoreceptor outer segment; protein localization to plasma membrane; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ruffle; secretory granule localization; synapse organization; synaptic transmission; vesicle-mediated transport; visual perception",PF01843;PF00612;PF00063;,,,,,,,,,MYO5A_HUMAN,Homo sapiens (Human),"actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; myelination [GO:0042552]; odontogenesis [GO:0042476]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; transport [GO:0006810]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]" comp135194_c1_seq3,1602,43.633,0.57828305,0,0,,3.00E-08,P55196,Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),GO:0034332; GO:0045177; GO:0007155; GO:0034329; GO:0005913; GO:0005911; GO:0007267; GO:0005829; GO:0005634; GO:0005886; GO:0008022; GO:0007165,adherens junction organization; apical part of cell; cell adhesion; cell junction assembly; cell-cell adherens junction; cell-cell junction; cell-cell signaling; cytosol; nucleus; plasma membrane; protein C-terminus binding; signal transduction,PF01843;PF00498;PF00595;PF00788;,,,,,,,,,AFAD_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp135194_c1_seq4,4797,44.6321,0.61293338,0,0,,0,P70569,Unconventional myosin-Vb (Myosin heavy chain myr 6),Unconventional myosin-Vb (Myosin heavy chain myr 6),GO:0005524; GO:0017137; GO:0043197; GO:0003774; GO:0016459; GO:0043025; GO:0048471; GO:0015031; GO:0032880,ATP binding; Rab GTPase binding; dendritic spine; motor activity; myosin complex; neuronal cell body; perinuclear region of cytoplasm; protein transport; regulation of protein localization,PF01843;PF00612;PF00063;,3.00E-176,CHOYP_MYO5A.3.4,,,,,,,MYO5B_RAT,Rattus norvegicus (Rat),endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880] comp135194_c1_seq5,3247,46.0117,0.67031637,0,0,,0,P70569,Unconventional myosin-Vb (Myosin heavy chain myr 6),Unconventional myosin-Vb (Myosin heavy chain myr 6),GO:0005524; GO:0017137; GO:0043197; GO:0003774; GO:0016459; GO:0043025; GO:0048471; GO:0015031; GO:0032880,ATP binding; Rab GTPase binding; dendritic spine; motor activity; myosin complex; neuronal cell body; perinuclear region of cytoplasm; protein transport; regulation of protein localization,PF01843;PF00612;PF00063;,7.00E-113,CHOYP_MYO5A.4.4,,,,,,,MYO5B_RAT,Rattus norvegicus (Rat),endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880] comp135194_c1_seq7,3223,46.0751,0.66753647,0,0,,8.00E-49,Q876G9,Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2),Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2),GO:0005524; GO:0007049; GO:0003774; GO:0016459; GO:0015031,ATP binding; cell cycle; motor activity; myosin complex; protein transport,PF01843;PF00063;PF02736;,3.00E-117,CHOYP_MYO5A.3.4,1.00E-30,ruditapes_c30878,,,,,MYO2_SACBA,Saccharomyces uvarum (strain ATCC 76518 / CBS 7001 / CLIB 283 / NBRC 10550 / MCYC 623 / NCYC 2669 / NRRL Y-11845) (Yeast) (Saccharomyces bayanus var. uvarum),cell cycle [GO:0007049]; protein transport [GO:0015031] comp135194_c1_seq9,940,45.6383,0.59546633,0,0,,,,,,,,,9.00E-112,CHOYP_MYO5A.2.4,,,,,,,,, comp135196_c1_seq2,489,40.0818,0.64793659,69,47,,9.00E-11,P42519,Protein Star,Protein Star,GO:0005794; GO:0000139; GO:0048149; GO:0046845; GO:0046667; GO:0035225; GO:0005789; GO:0038004; GO:0007173; GO:0061331; GO:0007476; GO:0016021; GO:0007498; GO:0016318; GO:0048477; GO:0097038; GO:0007422; GO:0042461; GO:0005886; GO:0000042; GO:0048865; GO:0007421; GO:0007601,"Golgi apparatus; Golgi membrane; behavioral response to ethanol; branched duct epithelial cell fate determination, open tracheal system; compound eye retinal cell programmed cell death; determination of genital disc primordium; endoplasmic reticulum membrane; epidermal growth factor receptor ligand maturation; epidermal growth factor receptor signaling pathway; epithelial cell proliferation involved in Malpighian tubule morphogenesis; imaginal disc-derived wing morphogenesis; integral to membrane; mesoderm development; ommatidial rotation; oogenesis; perinuclear endoplasmic reticulum; peripheral nervous system development; photoreceptor cell development; plasma membrane; protein targeting to Golgi; stem cell fate commitment; stomatogastric nervous system development; visual perception",,,,5.00E-65,ruditapes_c18175,,,,,STAR_DROME,Drosophila melanogaster (Fruit fly),"behavioral response to ethanol [GO:0048149]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; compound eye photoreceptor development [GO:0042051]; compound eye retinal cell programmed cell death [GO:0046667]; determination of genital disc primordium [GO:0035225]; epidermal growth factor receptor ligand maturation [GO:0038004]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; imaginal disc-derived wing morphogenesis [GO:0007476]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; protein targeting to Golgi [GO:0000042]; R7 cell development [GO:0045467]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; stem cell fate commitment [GO:0048865]; stomatogastric nervous system development [GO:0007421]; visual perception [GO:0007601]" comp135205_c0_seq1,676,40.0888,0.65177399,25,90,,5.00E-125,Q6NZW8,ADP-ribosylation factor-like protein 8B-A,ADP-ribosylation factor-like protein 8B-A,GO:0005525; GO:0051301; GO:0007059; GO:0031902; GO:0005765; GO:0007067; GO:0007264; GO:0005819,GTP binding; cell division; chromosome segregation; late endosome membrane; lysosomal membrane; mitosis; small GTPase mediated signal transduction; spindle,PF00025;,2.00E-137,CHOYP_ARL8A.1.1,7.00E-160,ruditapes_c15631,,,,,AR8BA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; small GTPase mediated signal transduction [GO:0007264] comp135206_c0_seq1,2500,36.64,0.50123118,6668,272,,6.00E-146,Q2TA38,Tektin-4,Tektin-4,GO:0030030; GO:0035085; GO:0005874; GO:0000226,cell projection organization; cilium axoneme; microtubule; microtubule cytoskeleton organization,,0,CHOYP_LOC100374062.1.1,1.00E-93,ruditapes_lrc17467,,,,,TEKT4_BOVIN,Bos taurus (Bovine),cell projection organization [GO:0030030] comp135208_c0_seq1,1333,39.6099,0.40651869,5,12,,0,Q6DGS3,Calcium/calmodulin-dependent protein kinase type II delta 2 chain (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase type II delta-A chain) (CaM kinase II subunit delta-A) (CaM-kinase II delta-A chain) (CaMK-II subunit delta-A),Calcium/calmodulin-dependent protein kinase type II delta 2 chain (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase type II delta-A chain) (CaM kinase II subunit delta-A) (CaM-kinase II delta-A chain) (CaMK-II subunit delta-A),GO:0005524; GO:0004683,ATP binding; calmodulin-dependent protein kinase activity,PF08332;PF00069;,,,,,,,,,KC2D2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp135208_c0_seq2,2169,39.1886,0.46711882,0,0,,0,Q95266,Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17),Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17),GO:0005524; GO:0000082; GO:0030315; GO:0043194; GO:0006816; GO:0004683; GO:0060048; GO:0014704; GO:0031594; GO:0043025; GO:0005634; GO:0018105; GO:0010613; GO:0046777; GO:0006468; GO:0060341; GO:0002028; GO:0033017,ATP binding; G1/S transition of mitotic cell cycle; T-tubule; axon initial segment; calcium ion transport; calmodulin-dependent protein kinase activity; cardiac muscle contraction; intercalated disc; neuromuscular junction; neuronal cell body; nucleus; peptidyl-serine phosphorylation; positive regulation of cardiac muscle hypertrophy; protein autophosphorylation; protein phosphorylation; regulation of cellular localization; regulation of sodium ion transport; sarcoplasmic reticulum membrane,PF08332;PF00069;,,,,,,,,,KCC2D_PIG,Sus scrofa (Pig),calcium ion transport [GO:0006816]; cardiac muscle contraction [GO:0060048]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897] comp135208_c0_seq3,2241,39.0004,0.44390584,0,0,,0,Q00168,Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17),Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17),GO:0005524; GO:0030424; GO:0005954; GO:0005516; GO:0004683; GO:0030425; GO:0007616; GO:0008049; GO:0007528; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0007268,ATP binding; axon; calcium- and calmodulin-dependent protein kinase complex; calmodulin binding; calmodulin-dependent protein kinase activity; dendrite; long-term memory; male courtship behavior; neuromuscular junction development; postsynaptic membrane; presynaptic active zone; regulation of filopodium assembly; regulation of ovulation; synaptic transmission,PF08332;PF00069;,0,CHOYP_LOC100533283.1.1,,,,,,,KCC2A_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; neuromuscular junction development [GO:0007528]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; sensory perception of pain [GO:0019233] comp135208_c0_seq4,968,40.0826,0.41948097,0,12,,5.00E-71,Q7TNJ7,Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III),Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III),GO:0005524; GO:0000139; GO:0005954; GO:0019722; GO:0004683; GO:0005737; GO:0043005; GO:0005886,ATP binding; Golgi membrane; calcium- and calmodulin-dependent protein kinase complex; calcium-mediated signaling; calmodulin-dependent protein kinase activity; cytoplasm; neuron projection; plasma membrane,PF00069;,,,,,,,,,KCC1G_RAT,Rattus norvegicus (Rat),calcium-mediated signaling [GO:0019722]; protein phosphorylation [GO:0006468] comp135208_c0_seq5,2256,39.0514,0.45199482,0,0,,3.00E-68,Q8RWL2,Calcium-dependent protein kinase 29 (EC 2.7.11.1),Calcium-dependent protein kinase 29 (EC 2.7.11.1),GO:0005524; GO:0005509; GO:0016020; GO:0004674,ATP binding; calcium ion binding; membrane; protein serine/threonine kinase activity,PF13499;PF00069;,,,,,,,,,CDPKT_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] comp135208_c0_seq6,2154,39.1365,0.45889073,0,0,,0,Q95266,Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17),Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17),GO:0005524; GO:0000082; GO:0030315; GO:0043194; GO:0006816; GO:0004683; GO:0060048; GO:0014704; GO:0031594; GO:0043025; GO:0005634; GO:0018105; GO:0010613; GO:0046777; GO:0006468; GO:0060341; GO:0002028; GO:0033017,ATP binding; G1/S transition of mitotic cell cycle; T-tubule; axon initial segment; calcium ion transport; calmodulin-dependent protein kinase activity; cardiac muscle contraction; intercalated disc; neuromuscular junction; neuronal cell body; nucleus; peptidyl-serine phosphorylation; positive regulation of cardiac muscle hypertrophy; protein autophosphorylation; protein phosphorylation; regulation of cellular localization; regulation of sodium ion transport; sarcoplasmic reticulum membrane,PF08332;PF00069;,0,CHOYP_LOC100533283.1.1,,,,,,,KCC2D_PIG,Sus scrofa (Pig),calcium ion transport [GO:0006816]; cardiac muscle contraction [GO:0060048]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897] comp135208_c0_seq7,1348,39.6884,0.41985706,0,3,,4.00E-74,Q24210,Peripheral plasma membrane protein CASK (dCASK) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase) (CAKI) (Camguk),Peripheral plasma membrane protein CASK (dCASK) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase) (CAKI) (Camguk),GO:0005524; GO:0007628; GO:0007615; GO:0007298; GO:0005954; GO:0004683; GO:0007155; GO:0007163; GO:0046331; GO:0007616; GO:0008049; GO:0072375; GO:0031594; GO:0007274; GO:0005886; GO:0008360; GO:0046928; GO:2000331; GO:0016081; GO:0048488; GO:0016080; GO:0061174,ATP binding; adult walking behavior; anesthesia-resistant memory; border follicle cell migration; calcium- and calmodulin-dependent protein kinase complex; calmodulin-dependent protein kinase activity; cell adhesion; establishment or maintenance of cell polarity; lateral inhibition; long-term memory; male courtship behavior; medium-term memory; neuromuscular junction; neuromuscular synaptic transmission; plasma membrane; regulation of cell shape; regulation of neurotransmitter secretion; regulation of terminal button organization; synaptic vesicle docking involved in exocytosis; synaptic vesicle endocytosis; synaptic vesicle targeting; type I terminal bouton,PF00625;PF02828;PF00595;PF00069;PF07653;,,,,,,,,,CSKP_DROME,Drosophila melanogaster (Fruit fly),adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; anesthesia-resistant memory [GO:0007615]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; establishment or maintenance of cell polarity [GO:0007163]; lateral inhibition [GO:0046331]; locomotion [GO:0040011]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; medium-term memory [GO:0072375]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; regulation of cell shape [GO:0008360]; regulation of locomotion [GO:0040012]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; sensory perception of pain [GO:0019233]; synaptic vesicle docking [GO:0016081]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080] comp135209_c0_seq1,1540,38.3766,0.49806097,105,580,,3.00E-63,Q8C1Z8,tRNA methyltransferase 10 homolog A (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 2),tRNA methyltransferase 10 homolog A (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 2),GO:0008168,methyltransferase activity,PF01746;,4.00E-43,CHOYP_LOC100123238.1.1,,,,,,,TM10A_MOUSE,Mus musculus (Mouse),magnesium ion homeostasis [GO:0010960]; tRNA methylation [GO:0030488] comp135214_c1_seq2,328,35.6707,0.57787422,8,26,,2.00E-23,P10073,Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50),Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,6.00E-11,ruditapes_c21757,,,,,ZSC22_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp135214_c1_seq3,205,35.122,0.65398382,4,39,,4.00E-17,Q5TC79,Zinc finger and BTB domain-containing protein 37,Zinc finger and BTB domain-containing protein 37,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT37_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135217_c0_seq1,1428,42.507,0.37874389,268,1072,,2.00E-169,Q9Y6V7,Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49),Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF00271;,0,CHOYP_DDX49.1.1,6.00E-63,ruditapes_c23934,,,,,DDX49_HUMAN,Homo sapiens (Human),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp135218_c0_seq1,1862,40.0107,0.3632288,0,0,,5.00E-40,Q4QR88,TIMELESS-interacting protein,TIMELESS-interacting protein,GO:0000076; GO:0051301; GO:0005737; GO:0031573; GO:0007067; GO:0000790; GO:0008284; GO:0048478,DNA replication checkpoint; cell division; cytoplasm; intra-S DNA damage checkpoint; mitosis; nuclear chromatin; positive regulation of cell proliferation; replication fork protection,PF07962;,,,,,,,,,TIPIN_RAT,Rattus norvegicus (Rat),cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication checkpoint [GO:0000076]; intra-S DNA damage checkpoint [GO:0031573]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; replication fork protection [GO:0048478] comp135218_c0_seq4,1775,39.9437,0.36540214,0,0,,4.00E-40,Q4QR88,TIMELESS-interacting protein,TIMELESS-interacting protein,GO:0000076; GO:0051301; GO:0005737; GO:0031573; GO:0007067; GO:0000790; GO:0008284; GO:0048478,DNA replication checkpoint; cell division; cytoplasm; intra-S DNA damage checkpoint; mitosis; nuclear chromatin; positive regulation of cell proliferation; replication fork protection,PF07962;,5.00E-55,CHOYP_TIPIN.2.2,,,,,,,TIPIN_RAT,Rattus norvegicus (Rat),cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication checkpoint [GO:0000076]; intra-S DNA damage checkpoint [GO:0031573]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; replication fork protection [GO:0048478] comp135222_c0_seq1,1362,35.1689,0.87950867,78,214,,5.00E-13,Q5NDL0,EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),GO:0005788; GO:0016262; GO:0006493,endoplasmic reticulum lumen; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation,PF04577;,,,,,,,,,EOGT_RAT,Rattus norvegicus (Rat),protein O-linked glycosylation [GO:0006493] comp135223_c0_seq1,1536,46.0286,0.47561909,13,34,,3.00E-68,Q6NY19,KN motif and ankyrin repeat domain-containing protein 3 (Ankyrin repeat domain-containing protein 47),KN motif and ankyrin repeat domain-containing protein 3 (Ankyrin repeat domain-containing protein 47),,,PF12796;PF12075;,1.00E-74,CHOYP_LOC100218754.1.1,,,,,,,KANK3_HUMAN,Homo sapiens (Human), comp135223_c0_seq2,1703,45.5079,0.47397574,14,40,,1.00E-85,Q14678,KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein),KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein),GO:0008013; GO:0005737; GO:0035024; GO:0030837; GO:0030336; GO:0046627; GO:2000393; GO:0010977; GO:1900028; GO:1900025; GO:0005634; GO:0030177; GO:0035413; GO:0090303; GO:2000114; GO:0006355; GO:0032587; GO:0006351,"beta-catenin binding; cytoplasm; negative regulation of Rho protein signal transduction; negative regulation of actin filament polymerization; negative regulation of cell migration; negative regulation of insulin receptor signaling pathway; negative regulation of lamellipodium morphogenesis; negative regulation of neuron projection development; negative regulation of ruffle assembly; negative regulation of substrate adhesion-dependent cell spreading; nucleus; positive regulation of Wnt receptor signaling pathway; positive regulation of catenin import into nucleus; positive regulation of wound healing; regulation of establishment of cell polarity; regulation of transcription, DNA-dependent; ruffle membrane; transcription, DNA-dependent",PF12796;PF12075;,3.00E-51,CHOYP_LOC100538765.1.1,,,,,,,KANK1_HUMAN,Homo sapiens (Human),"negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135225_c1_seq1,458,43.2314,0.47932559,18,88,,1.00E-33,Q8N567,Zinc finger CCHC domain-containing protein 9,Zinc finger CCHC domain-containing protein 9,GO:0010923; GO:0003676; GO:0008270,negative regulation of phosphatase activity; nucleic acid binding; zinc ion binding,PF00098;,2.00E-22,CHOYP_ZCHC9.2.2,,,,,,,ZCHC9_HUMAN,Homo sapiens (Human),"negative regulation of phosphatase activity [GO:0010923]; transcription, DNA-templated [GO:0006351]" comp135226_c0_seq2,633,41.7062,0.18371532,4,15,,3.00E-06,Q6DFB8,Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),GO:0055087; GO:0005634; GO:0035327,Ski complex; nucleus; transcriptionally active chromatin,PF13181;,,,,,,,,,TTC37_XENLA,Xenopus laevis (African clawed frog), comp135226_c0_seq3,364,42.033,0.12816108,0,0,,7.00E-07,Q6DFB8,Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),GO:0055087; GO:0005634; GO:0035327,Ski complex; nucleus; transcriptionally active chromatin,PF13181;,,,,,,,,,TTC37_XENLA,Xenopus laevis (African clawed frog), comp135229_c0_seq1,2256,40.6472,0.42045463,877,5023,,0,Q2KID6,Pleiotropic regulator 1,Pleiotropic regulator 1,GO:0008380; GO:0071013; GO:0006397; GO:0016607,RNA splicing; catalytic step 2 spliceosome; mRNA processing; nuclear speck,PF00400;,3.00E-172,CHOYP_PLRG1.1.1,,,,,,,PLRG1_BOVIN,Bos taurus (Bovine),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein localization to nucleus [GO:0034504]" comp135230_c0_seq2,1209,32.9198,0.95591299,139,398,,1.00E-15,A5PK65,D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase),D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase),GO:0033981; GO:0005737; GO:0042438,D-dopachrome decarboxylase activity; cytoplasm; melanin biosynthetic process,PF01187;,,,,,,,,,DOPD_BOVIN,Bos taurus (Bovine),melanin biosynthetic process [GO:0042438] comp135231_c0_seq1,2636,38.7709,0.64636075,1378,30,,3.00E-132,O57429,Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2),Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2),GO:0046872; GO:0048471; GO:0016579; GO:0004221; GO:0006511; GO:0004843,metal ion binding; perinuclear region of cytoplasm; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,8.00E-61,CHOYP_LOC100114408.1.1,,,,,,,UBP2_CHICK,Gallus gallus (Chicken),protein deubiquitination [GO:0016579]; rhythmic process [GO:0048511]; ubiquitin-dependent protein catabolic process [GO:0006511] comp135232_c0_seq1,1112,36.6906,0.70596042,40,272,,2.00E-16,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135234_c0_seq1,1061,48.5391,0.62493266,3,408,female>male,5.00E-151,O94788,Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)),Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)),GO:0004028; GO:0042904; GO:0009952; GO:0001568; GO:0048738; GO:0071300; GO:0005737; GO:0005829; GO:0009855; GO:0031076; GO:0048566; GO:0035115; GO:0060324; GO:0003007; GO:0030902; GO:0001822; GO:0001889; GO:0030324; GO:0007494; GO:0016331; GO:0008285; GO:0014032; GO:0021915; GO:0030182; GO:0005634; GO:0031016; GO:0048471; GO:0021983; GO:0043065; GO:0008284; GO:0010628; GO:0009954; GO:0001936; GO:0034097; GO:0032355; GO:0033189; GO:0016918; GO:0001758; GO:0042574; GO:0042573; GO:0048384; GO:0042572; GO:0035799; GO:0006776,3-chloroallyl aldehyde dehydrogenase activity; 9-cis-retinoic acid biosynthetic process; anterior/posterior pattern specification; blood vessel development; cardiac muscle tissue development; cellular response to retinoic acid; cytoplasm; cytosol; determination of bilateral symmetry; embryonic camera-type eye development; embryonic digestive tract development; embryonic forelimb morphogenesis; face development; heart morphogenesis; hindbrain development; kidney development; liver development; lung development; midgut development; morphogenesis of embryonic epithelium; negative regulation of cell proliferation; neural crest cell development; neural tube development; neuron differentiation; nucleus; pancreas development; perinuclear region of cytoplasm; pituitary gland development; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of gene expression; proximal/distal pattern formation; regulation of endothelial cell proliferation; response to cytokine stimulus; response to estradiol stimulus; response to vitamin A; retinal binding; retinal dehydrogenase activity; retinal metabolic process; retinoic acid metabolic process; retinoic acid receptor signaling pathway; retinol metabolic process; ureter maturation; vitamin A metabolic process,PF00171;,2.00E-62,CHOYP_ALDH2.3.3,7.00E-86,ruditapes_c30992,,,,,AL1A2_HUMAN,Homo sapiens (Human),9-cis-retinoic acid biosynthetic process [GO:0042904]; anterior/posterior pattern specification [GO:0009952]; blood vessel development [GO:0001568]; cardiac muscle tissue development [GO:0048738]; cellular response to retinoic acid [GO:0071300]; determination of bilateral symmetry [GO:0009855]; embryonic camera-type eye development [GO:0031076]; embryonic digestive tract development [GO:0048566]; embryonic forelimb morphogenesis [GO:0035115]; face development [GO:0060324]; heart morphogenesis [GO:0003007]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; liver development [GO:0001889]; lung development [GO:0030324]; midgut development [GO:0007494]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of cell proliferation [GO:0008285]; neural crest cell development [GO:0014032]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; pituitary gland development [GO:0021983]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; proximal/distal pattern formation [GO:0009954]; regulation of endothelial cell proliferation [GO:0001936]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to vitamin A [GO:0033189]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; retinoic acid receptor signaling pathway [GO:0048384]; retinol metabolic process [GO:0042572]; ureter maturation [GO:0035799]; vitamin A metabolic process [GO:0006776] comp135234_c0_seq2,968,38.5331,0.68699116,5,549,female>male,2.00E-73,Q29491,"Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)","Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)",GO:0004029; GO:0005737; GO:0006068,aldehyde dehydrogenase (NAD) activity; cytoplasm; ethanol catabolic process,PF00171;,8.00E-43,CHOYP_NEMVEDRAFT_V1G181421.1.1,8.00E-72,ruditapes2_c212,,,,,ALDH2_MACPR,Macroscelides proboscideus (Short-eared elephant shrew),ethanol catabolic process [GO:0006068] comp135235_c1_seq7,1196,39.8829,0.42834168,37,437,,1.00E-101,Q99MZ7,Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38),Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38),GO:0030497; GO:0005739; GO:0005778; GO:0033306; GO:0019166,fatty acid elongation; mitochondrion; peroxisomal membrane; phytol metabolic process; trans-2-enoyl-CoA reductase (NADPH) activity,,7.00E-70,CHOYP_PECR.1.1,1.00E-115,ruditapes_c18624,,,,,PECR_MOUSE,Mus musculus (Mouse),fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306] comp135238_c0_seq1,984,42.2764,0.75133563,0,0,,,,,,,,,2.00E-18,CHOYP_LOC100883571.1.1,,,,,,,,, comp135238_c0_seq3,1723,46.8369,0.62688572,7,0,,7.00E-53,Q5BJU7,Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1),Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1),GO:0030036; GO:0005856; GO:0030027; GO:0072673; GO:0005741,actin cytoskeleton organization; cytoskeleton; lamellipodium; lamellipodium morphogenesis; mitochondrial outer membrane,PF02205;,7.00E-15,CHOYP_LOC662022.1.1,,,,,,,WASF1_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; lamellipodium morphogenesis [GO:0072673]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; Rac protein signal transduction [GO:0016601] comp135248_c0_seq3,703,45.2347,0.44641815,12,2,,8.00E-54,Q5F413,Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like),Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like),GO:0008060; GO:0043547; GO:0032312; GO:0008270,ARF GTPase activator activity; positive regulation of GTPase activity; regulation of ARF GTPase activity; zinc ion binding,PF01412;,7.00E-67,CHOYP_LOC100120440.1.1,2.00E-78,ruditapes_c26884,,,,,SMAP2_CHICK,Gallus gallus (Chicken), comp135250_c0_seq1,1361,42.3218,1.09916501,2947,3,male>female,,,,,,,,3.00E-25,CHOYP_BRAFLDRAFT_117083.1.3,,,,,,,,, comp135255_c0_seq1,1168,41.1815,0.44856488,61,976,,6.00E-84,Q71R50,Dehydrogenase/reductase SDR family member 11 (EC 1.-.-.-),Dehydrogenase/reductase SDR family member 11 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 24C member 1),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF00106;,2.00E-14,CHOYP_LOC101167642.1.1,,,,,,,DHR11_CHICK,Gallus gallus (Chicken), comp135256_c0_seq1,4383,37.0522,0.21418409,276,379,,3.00E-13,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp135258_c2_seq2,615,44.878,1.09032685,0,4,,6.00E-12,Q55GI5,"L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)","L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)",GO:0047545; GO:0005739,2-hydroxyglutarate dehydrogenase activity; mitochondrion,PF01266;,,,,,,,,,L2HDH_DICDI,Dictyostelium discoideum (Slime mold), comp135258_c2_seq4,958,41.1273,1.22343855,122,97,,2.00E-14,P75063,Uncharacterized protein MG039 homolog,Uncharacterized protein MG039 homolog,GO:0016491,oxidoreductase activity,PF01266;,,,,,,,,,Y051_MYCPN,Mycoplasma pneumoniae (strain ATCC 29342 / M129), comp135258_c2_seq5,744,41.6667,1.10188671,12,6,,6.00E-14,Q9N4Z0,"L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)","L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)",GO:0047545; GO:0005739,2-hydroxyglutarate dehydrogenase activity; mitochondrion,PF01266;,,,,,,,,,L2HDH_CAEEL,Caenorhabditis elegans, comp135258_c2_seq6,693,45.1659,1.10380273,6,0,,3.00E-13,P75063,Uncharacterized protein MG039 homolog,Uncharacterized protein MG039 homolog,GO:0016491,oxidoreductase activity,PF01266;,,,,,,,,,Y051_MYCPN,Mycoplasma pneumoniae (strain ATCC 29342 / M129), comp135260_c0_seq1,1193,41.8273,0.36644724,0,9,,3.00E-70,Q91WT4,DnaJ homolog subfamily C member 17,DnaJ homolog subfamily C member 17,GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00226;PF00076;,1.00E-48,CHOYP_DNAJC17.1.1,,,,,,,DJC17_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]" comp135260_c0_seq2,1216,41.6118,0.34397448,5,9,,9.00E-72,Q2KI83,DnaJ homolog subfamily C member 17,DnaJ homolog subfamily C member 17,GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00226;PF00076;,,,,,,,,,DJC17_BOVIN,Bos taurus (Bovine),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]" comp135261_c0_seq1,1656,34.2995,0.86302115,981,4363,,8.00E-13,Q7T3U0,Zygote arrest protein 1 (Oocyte-specific maternal effect factor),Zygote arrest protein 1 (Oocyte-specific maternal effect factor),GO:0005737; GO:0007275,cytoplasm; multicellular organismal development,PF13695;,,,,,,,,,ZAR1_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275] comp135262_c0_seq2,1361,38.8685,0.45551864,9,35,,5.00E-120,Q5R7L7,Ras-related protein Rab-5C,Ras-related protein Rab-5C,GO:0019003; GO:0005525; GO:0031901; GO:0005811; GO:0005886; GO:0015031; GO:0007264,GDP binding; GTP binding; early endosome membrane; lipid particle; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,5.00E-155,CHOYP_LOC578627.1.1,2.00E-44,ruditapes_c29823,,,,,RAB5C_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),plasma membrane to endosome transport [GO:0048227]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp135264_c0_seq1,1392,42.8879,0.69456205,62,147,,2.00E-165,Q7ZYD5,Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),GO:0005509; GO:0016021; GO:0005743; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF13499;PF00153;,4.00E-80,CHOYP_LOC588410.1.1,2.00E-38,ruditapes_c27564,,,,,SCMC2_XENLA,Xenopus laevis (African clawed frog),transmembrane transport [GO:0055085] comp135264_c1_seq1,2929,39.365,0.45864495,2123,11,male>female,2.00E-93,Q95J53,BTB/POZ domain-containing protein 16,BTB/POZ domain-containing protein 16,,,,2.00E-119,CHOYP_LOC100370504.1.2,,,,,,,BTBDG_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp135264_c2_seq1,424,40.566,0.74956325,0,11,,2.00E-25,O18757,Calcium-binding mitochondrial carrier protein SCaMC-1 (Peroxisomal Ca(2+)-dependent solute carrier) (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24),Calcium-binding mitochondrial carrier protein SCaMC-1 (Peroxisomal Ca(2+)-dependent solute carrier) (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24),GO:0005509; GO:0016021; GO:0005743; GO:0005777; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; peroxisome; transmembrane transport,PF13499;PF00153;,,,,,,,,,SCMC1_RABIT,Oryctolagus cuniculus (Rabbit),ATP transport [GO:0015867]; cellular response to calcium ion [GO:0071277]; cellular response to oxidative stress [GO:0034599]; mitochondrial transport [GO:0006839]; regulation of cell death [GO:0010941] comp135264_c2_seq2,451,41.02,0.74133448,6,2,,3.00E-10,Q6NYZ6,Calcium-binding mitochondrial carrier protein SCaMC-2-A (Small calcium-binding mitochondrial carrier protein 2-A) (Solute carrier family 25 member 25-A),Calcium-binding mitochondrial carrier protein SCaMC-2-A (Small calcium-binding mitochondrial carrier protein 2-A) (Solute carrier family 25 member 25-A),GO:0005509; GO:0016021; GO:0005743; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,,,,,,,,,SCM2A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),translation [GO:0006412]; transmembrane transport [GO:0055085] comp135265_c0_seq2,1022,34.1487,0.67874269,485,134,,1.00E-38,Q8IZ02,Leucine-rich repeat-containing protein 34,Leucine-rich repeat-containing protein 34,,,PF13516;,,,,,,,,,LRC34_HUMAN,Homo sapiens (Human), comp135265_c0_seq3,870,42.5287,0.48444196,291,66,,1.00E-65,Q9DAM1,Leucine-rich repeat-containing protein 34,Leucine-rich repeat-containing protein 34,,,PF13516;,2.00E-88,CHOYP_LOC100374522.1.1,,,,,,,LRC34_MOUSE,Mus musculus (Mouse), comp135266_c2_seq2,1921,43.1026,0.58861238,30,28,,6.00E-140,Q99523,Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3),Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3),GO:0005794; GO:0032580; GO:0006895; GO:0009986; GO:0030136; GO:0005905; GO:0030425; GO:0005769; GO:0006897; GO:0005789; GO:0010008; GO:0008333; GO:0032509; GO:0008625; GO:0046323; GO:0016021; GO:0005765; GO:0007275; GO:0014902; GO:0051005; GO:0010465; GO:0043025; GO:0007218; GO:0030379; GO:0048011; GO:0031965; GO:0001503; GO:0048471; GO:0005886; GO:0048227; GO:0010468; GO:0032868; GO:0030140; GO:0016050,"Golgi apparatus; Golgi cisterna membrane; Golgi to endosome transport; cell surface; clathrin-coated vesicle; coated pit; dendrite; early endosome; endocytosis; endoplasmic reticulum membrane; endosome membrane; endosome to lysosome transport; endosome transport via multivesicular body sorting pathway; extrinsic apoptotic signaling pathway via death domain receptors; glucose import; integral to membrane; lysosomal membrane; multicellular organismal development; myotube differentiation; negative regulation of lipoprotein lipase activity; nerve growth factor receptor activity; neuronal cell body; neuropeptide signaling pathway; neurotensin receptor activity, non-G-protein coupled; neurotrophin TRK receptor signaling pathway; nuclear membrane; ossification; perinuclear region of cytoplasm; plasma membrane; plasma membrane to endosome transport; regulation of gene expression; response to insulin stimulus; trans-Golgi network transport vesicle; vesicle organization",PF15902;PF15901;,2.00E-34,CHOYP_LOC100313736.1.1,,,,,,,SORT_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; endosome transport via multivesicular body sorting pathway [GO:0032509]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose import [GO:0046323]; Golgi to endosome transport [GO:0006895]; G-protein coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; myotube differentiation [GO:0014902]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of lipoprotein lipase activity [GO:0051005]; neuropeptide signaling pathway [GO:0007218]; neurotrophin TRK receptor signaling pathway [GO:0048011]; ossification [GO:0001503]; plasma membrane to endosome transport [GO:0048227]; positive regulation of epithelial cell apoptotic process [GO:1904037]; regulation of gene expression [GO:0010468]; response to insulin [GO:0032868]; vesicle organization [GO:0016050] comp135268_c0_seq2,889,43.1946,0.38637954,0,0,,2.00E-12,Q55G81,TFIIH basal transcription factor complex helicase repD subunit (EC 3.6.4.12) (DNA excision repair cross-complementing protein-2 homolog) (DNA repair protein D),TFIIH basal transcription factor complex helicase repD subunit (EC 3.6.4.12) (DNA excision repair cross-complementing protein-2 homolog) (DNA repair protein D),GO:0051539; GO:0005524; GO:0043141; GO:0003677; GO:0000442; GO:0000443; GO:0000287; GO:0006289; GO:0006355; GO:0006366,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent 5'-3' DNA helicase activity; DNA binding; SSL2-core TFIIH complex portion of NEF3 complex; SSL2-core TFIIH complex portion of holo TFIIH complex; magnesium ion binding; nucleotide-excision repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF06733;PF06777;PF13307;,,,,,,,,,ERCC2_DICDI,Dictyostelium discoideum (Slime mold),"cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp135268_c0_seq5,1517,43.9684,0.34276904,58,20,,2.00E-120,Q9BX63,Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1),Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0000077; GO:0005737; GO:0006302; GO:0046872; GO:0031965; GO:0006357,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA damage checkpoint; cytoplasm; double-strand break repair; metal ion binding; nuclear membrane; regulation of transcription from RNA polymerase II promoter",PF06733;PF13307;,4.00E-43,CHOYP_FANCJ.1.1,,,,,,,FANCJ_HUMAN,Homo sapiens (Human),cellular response to vitamin [GO:0071295]; DNA damage checkpoint [GO:0000077]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; negative regulation of cell proliferation [GO:0008285]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; strand displacement [GO:0000732] comp135269_c0_seq1,1468,42.3706,0.54697238,14,37,,7.00E-57,Q4R5X9,Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A),Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A),GO:0000077; GO:0006281; GO:0030896; GO:0008853; GO:0090305,DNA damage checkpoint; DNA repair; checkpoint clamp complex; exodeoxyribonuclease III activity; nucleic acid phosphodiester bond hydrolysis,PF04139;,,,,,,,,,RAD9A_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281] comp135269_c0_seq2,1471,42.4881,0.57303282,17,18,,1.00E-57,Q5E9X8,Cell cycle checkpoint control protein RAD9B (DNA repair exonuclease rad9 homolog B),Cell cycle checkpoint control protein RAD9B (DNA repair exonuclease rad9 homolog B),GO:0000077; GO:0006281; GO:0030896,DNA damage checkpoint; DNA repair; checkpoint clamp complex,PF04139;,1.00E-67,CHOYP_LOC100891745.1.1,,,,,,,RAD9B_BOVIN,Bos taurus (Bovine),cellular response to ionizing radiation [GO:0071479]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; intra-S DNA damage checkpoint [GO:0031573]; nucleic acid phosphodiester bond hydrolysis [GO:0090305] comp135270_c0_seq3,654,43.4251,0.88447319,3,13,,2.00E-07,Q8WMH2,Neuroligin-3 (Gliotactin homolog) (Fragment),Neuroligin-3 (Gliotactin homolog) (Fragment),GO:0007155; GO:0030054; GO:0009986; GO:0005887; GO:0042043; GO:0004872; GO:0045202; GO:0007416,cell adhesion; cell junction; cell surface; integral to plasma membrane; neurexin family protein binding; receptor activity; synapse; synapse assembly,PF00135;,,,,,,,,,NLGN3_MACMU,Macaca mulatta (Rhesus macaque),cell adhesion [GO:0007155] comp135270_c0_seq5,1312,41.5396,0.8184681,0,0,,8.00E-23,O62763,Acetylcholinesterase (AChE) (EC 3.1.1.7),Acetylcholinesterase (AChE) (EC 3.1.1.7),GO:0003990; GO:0031225; GO:0004091; GO:0030054; GO:0005576; GO:0042135; GO:0005886; GO:0045202,acetylcholinesterase activity; anchored to membrane; carboxylesterase activity; cell junction; extracellular region; neurotransmitter catabolic process; plasma membrane; synapse,PF08674;PF00135;,,,,,,,,,ACES_FELCA,Felis catus (Cat) (Felis silvestris catus),acetylcholine catabolic process [GO:0006581] comp135270_c0_seq6,1296,41.6667,0.82248219,0,0,,8.00E-23,O62763,Acetylcholinesterase (AChE) (EC 3.1.1.7),Acetylcholinesterase (AChE) (EC 3.1.1.7),GO:0003990; GO:0031225; GO:0004091; GO:0030054; GO:0005576; GO:0042135; GO:0005886; GO:0045202,acetylcholinesterase activity; anchored to membrane; carboxylesterase activity; cell junction; extracellular region; neurotransmitter catabolic process; plasma membrane; synapse,PF08674;PF00135;,,,,,,,,,ACES_FELCA,Felis catus (Cat) (Felis silvestris catus),acetylcholine catabolic process [GO:0006581] comp135270_c1_seq1,277,41.5162,0.68138143,0,29,,9.00E-25,P30122,Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment),GO:0047372; GO:0004091; GO:0005829; GO:0005615; GO:0016042; GO:0004771; GO:0004806,acylglycerol lipase activity; carboxylesterase activity; cytosol; extracellular space; lipid catabolic process; sterol esterase activity; triglyceride lipase activity,PF00135;,,,,,,,,,CEL_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp135271_c2_seq1,1367,41.624,0.53824391,138,169,,5.00E-27,Q803E1,Uncharacterized protein C17orf85 homolog,Nuclear cap-binding protein subunit 3,GO:0000166,nucleotide binding,PF10309;,9.00E-19,CHOYP_LOC100878601.1.1,,,,,,,CQ085_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),7-methylguanosine mRNA capping [GO:0006370]; mRNA transport [GO:0051028] comp135277_c0_seq1,2449,41.7313,0.45526348,660,5199,,2.00E-149,Q8R2N2,Cirhin (Testis-expressed gene 292 protein),U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (Testis-expressed gene 292 protein),GO:0030490; GO:0006355; GO:0034455; GO:0006351,"maturation of SSU-rRNA; regulation of transcription, DNA-dependent; t-UTP complex; transcription, DNA-dependent",PF00400;,7.00E-61,CHOYP_LOC100180054.1.1,,,,,,,CIR1A_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA [GO:0030490]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135280_c0_seq1,1073,41.2861,0.64404522,22,1005,,1.00E-54,Q9BDY7,Angiopoietin-2 (ANG-2),Angiopoietin-2 (ANG-2),GO:0001525; GO:0030154; GO:0005576; GO:0046872,angiogenesis; cell differentiation; extracellular region; metal ion binding,PF00147;,5.00E-14,CHOYP_FIBB.1.3,,,,,,,ANGP2_PIG,Sus scrofa (Pig),angiogenesis [GO:0001525]; cell differentiation [GO:0030154] comp135282_c1_seq1,703,40.6828,0.413207,12,75,,7.00E-33,Q7T320,RAB6-interacting golgin (N-terminal kinase-like-binding protein 1) (NTKL-BP1) (NTKL-binding protein 1) (SCY1-like 1-binding protein 1) (SCYL1-BP1) (SCYL1-binding protein 1),RAB6-interacting golgin (N-terminal kinase-like-binding protein 1) (NTKL-BP1) (NTKL-binding protein 1) (SCY1-like 1-binding protein 1) (SCYL1-BP1) (SCYL1-binding protein 1),GO:0005794,Golgi apparatus,,4.00E-13,CHOYP_GORAB.2.2,,,,,,,GORAB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp135284_c0_seq2,599,40.5676,0.77256924,61,91,,9.00E-19,Q9BQE4,Selenoprotein S (SelS) (VCP-interacting membrane protein),Selenoprotein S (SelS) (VCP-interacting membrane protein),GO:0006983; GO:0030433; GO:0016209; GO:0045454; GO:0032869; GO:0071222; GO:0034599; GO:0005881; GO:0030968; GO:0030176; GO:0034362; GO:0002865; GO:0046325; GO:0045719; GO:0032715; GO:1902236; GO:2000110; GO:0051771; GO:0032720; GO:0005886; GO:0004872; GO:0006111; GO:0080164; GO:0009749; GO:0051775; GO:0030970; GO:0008430; GO:0034361,"ER overload response; ER-associated protein catabolic process; antioxidant activity; cell redox homeostasis; cellular response to insulin stimulus; cellular response to lipopolysaccharide; cellular response to oxidative stress; cytoplasmic microtubule; endoplasmic reticulum unfolded protein response; integral to endoplasmic reticulum membrane; low-density lipoprotein particle; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of glucose import; negative regulation of glycogen biosynthetic process; negative regulation of interleukin-6 production; negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; negative regulation of macrophage apoptotic process; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of tumor necrosis factor production; plasma membrane; receptor activity; regulation of gluconeogenesis; regulation of nitric oxide metabolic process; response to glucose stimulus; response to redox state; retrograde protein transport, ER to cytosol; selenium binding; very-low-density lipoprotein particle",PF06936;,,,4.00E-16,ruditapes_c7386,,,,,SELS_HUMAN,Homo sapiens (Human),"cell redox homeostasis [GO:0045454]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; ER overload response [GO:0006983]; establishment of protein localization [GO:0045184]; negative regulation of acute inflammatory response to antigenic stimulus [GO:0002865]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of gluconeogenesis [GO:0006111]; regulation of nitric oxide metabolic process [GO:0080164]; response to glucose [GO:0009749]; response to redox state [GO:0051775]; retrograde protein transport, ER to cytosol [GO:0030970]" comp135285_c0_seq1,1632,40.5637,0.49952744,114,329,,2.00E-13,O55176,E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 6.3.2.-),E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 6.3.2.-),GO:0005737; GO:0030163; GO:0004842; GO:0008270,cytoplasm; protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,PJA1_MOUSE,Mus musculus (Mouse),protein catabolic process [GO:0030163] comp135287_c0_seq1,1272,39.6226,0.66070919,175,365,,7.00E-73,Q5SUC9,"Protein SCO1 homolog, mitochondrial","Protein SCO1 homolog, mitochondrial",GO:0006878; GO:0005507; GO:0006825; GO:0005743; GO:0005739; GO:0030016; GO:0008535,cellular copper ion homeostasis; copper ion binding; copper ion transport; mitochondrial inner membrane; mitochondrion; myofibril; respiratory chain complex IV assembly,PF02630;,3.00E-24,CHOYP_LOC657827.1.1,,,,,,,SCO1_MOUSE,Mus musculus (Mouse),cellular copper ion homeostasis [GO:0006878]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799] comp135301_c0_seq1,488,35.4508,0.58979074,36,45,,2.00E-13,Q80V63,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_MOUSE,Mus musculus (Mouse),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp135301_c1_seq1,428,35.7477,0.95628094,13,33,,2.00E-17,C9JN71,Zinc finger protein 878,Zinc finger protein 878,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN878_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135302_c0_seq1,2044,31.2622,0.48647053,67,475,,1.00E-13,Q5NVQ1,"HIG1 domain family member 1A, mitochondrial","HIG1 domain family member 1A, mitochondrial",GO:0016021; GO:0005743; GO:0043066; GO:0055114; GO:0043234; GO:0070469,integral to membrane; mitochondrial inner membrane; negative regulation of apoptotic process; oxidation-reduction process; protein complex; respiratory chain,PF04588;,,,,,,,,,HIG1A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidation-reduction process [GO:0055114]; positive regulation of protein serine/threonine kinase activity [GO:0071902] comp135305_c2_seq1,1170,40.7692,0.39603091,71,81,,3.00E-63,P60330,Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase),Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase),GO:0005813; GO:0008234; GO:0005737; GO:0045143; GO:0000212; GO:0000070; GO:0005634; GO:0008233; GO:0006508,centrosome; cysteine-type peptidase activity; cytoplasm; homologous chromosome segregation; meiotic spindle organization; mitotic sister chromatid segregation; nucleus; peptidase activity; proteolysis,PF03568;,,,,,,,,,ESPL1_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; homologous chromosome segregation [GO:0045143]; meiosis I [GO:0007127]; meiotic chromosome separation [GO:0051307]; meiotic spindle organization [GO:0000212]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of mitotic sister chromatid separation [GO:1901970] comp135307_c0_seq2,978,33.1288,0.54782423,62,214,,1.00E-58,Q86V88,Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48),Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48),GO:0046872; GO:0035335; GO:0004725,metal ion binding; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF12689;,9.00E-36,CHOYP_LOC100877618.1.1,,,,,,,MGDP1_HUMAN,Homo sapiens (Human), comp135312_c0_seq1,3317,35.9662,0.45257544,2457,10130,,0,Q6NVU2,Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16),Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16),GO:0051301; GO:0032154; GO:0000777; GO:0005977; GO:0046872; GO:0030496; GO:0005739; GO:0007067; GO:0007084; GO:0016607; GO:0005730; GO:0006470; GO:0004722,cell division; cleavage furrow; condensed chromosome kinetochore; glycogen metabolic process; metal ion binding; midbody; mitochondrion; mitosis; mitotic nuclear envelope reassembly; nuclear speck; nucleolus; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00149;PF16891;,0,CHOYP_PPP1CC.1.1,7.00E-29,ruditapes_c17178,,,,,PPIG_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),angiogenesis [GO:0001525]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope reassembly [GO:0007084]; protein dephosphorylation [GO:0006470] comp135314_c0_seq1,1539,46.3938,0.62850756,137,960,,7.00E-127,P38942,4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-),4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-),GO:0006084; GO:0016740,acetyl-CoA metabolic process; transferase activity,PF13336;PF02550;,4.00E-125,CHOYP_NEMVEDRAFT_V1G237598.1.1,,,,,,,CAT2_CLOK5,Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680),acetyl-CoA metabolic process [GO:0006084] comp135316_c0_seq2,899,42.2692,0.50539146,2,11,,3.00E-17,Q6QBQ4,Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3),Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3),GO:0006915; GO:0071222; GO:0016021; GO:0031966,apoptotic process; cellular response to lipopolysaccharide; integral to membrane; mitochondrial membrane,PF03803;,,,,,,,,,PLS3_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; glucose homeostasis [GO:0042593] comp135317_c0_seq1,2940,31.3265,0.4301128,2800,13479,,6.00E-67,P55061,Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6),Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6),GO:0006915; GO:0005783; GO:0005789; GO:0005887; GO:0043066; GO:0005634; GO:0006986,apoptotic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; negative regulation of apoptotic process; nucleus; response to unfolded protein,,,,2.00E-48,ruditapes_c16800,,,,,BI1_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; lung development [GO:0030324]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of immunoglobulin secretion [GO:0051025]; negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response [GO:1904721]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; response to L-glutamate [GO:1902065]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283] comp135320_c1_seq2,1090,39.9083,1.01811326,28,78,,8.00E-18,Q9Y5X4,Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor),Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor),GO:0004879; GO:0005654; GO:0007602; GO:0043565; GO:0003707; GO:0006367; GO:0007601; GO:0008270,ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleoplasm; phototransduction; sequence-specific DNA binding; steroid hormone receptor activity; transcription initiation from RNA polymerase II promoter; visual perception; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR2E3_HUMAN,Homo sapiens (Human),eye photoreceptor cell development [GO:0042462]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; phototransduction [GO:0007602]; positive regulation of rhodopsin gene expression [GO:0045872]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; visual perception [GO:0007601] comp135320_c1_seq4,500,35.6,0.89464644,0,0,,,,,,,,,8.00E-14,CHOYP_NEMVEDRAFT_V1G114090.1.1,6.00E-13,ruditapes_c30217,,,,,,, comp135321_c0_seq3,879,36.0637,0.66608325,42,2,,,,,,,,,2.00E-36,CHOYP_LOC100898095.18.19,,,,,,,,, comp135323_c0_seq1,3472,32.7189,0.41889197,4051,10107,,2.00E-39,Q5ZML3,"Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1)","Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1)",GO:0003723; GO:0008380; GO:0006397; GO:0000166; GO:0005634,RNA binding; RNA splicing; mRNA processing; nucleotide binding; nucleus,PF00076;,9.00E-55,CHOYP_ISCW_ISCW014398.1.3,,,,,,,SRSF1_CHICK,Gallus gallus (Chicken),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp135325_c7_seq5,216,37.037,0.13699789,11,18,,,,,,,,,,,3.00E-12,ruditapes_c21699,,,,,,, comp135327_c1_seq1,1181,36.8332,0.4001357,774,175,,2.00E-27,A2VDD2,Tctex1 domain-containing protein 1-B (Fragment),Tctex1 domain-containing protein 1-B (Fragment),,,PF03645;,,,,,,,,,TC1DB_XENLA,Xenopus laevis (African clawed frog), comp135329_c0_seq10,1013,37.5123,0.73933721,161,1336,,,,,,,,,,,3.00E-14,ruditapes_c9370,,,,,,, comp135330_c0_seq1,1462,32.0109,0.45662533,1589,13180,,3.00E-24,Q9P0S9,Transmembrane protein 14C,Transmembrane protein 14C,GO:0006783; GO:0016021; GO:0031966,heme biosynthetic process; integral to membrane; mitochondrial membrane,PF03647;,,,8.00E-49,ruditapes2_c3923,,,,,TM14C_HUMAN,Homo sapiens (Human),heme biosynthetic process [GO:0006783] comp135331_c0_seq1,2494,42.903,0.28499939,67,39,,3.00E-84,P82094,TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa),TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa),GO:0003677; GO:0005794; GO:0000139; GO:0001675; GO:0071407; GO:0042742; GO:0008584; GO:0010629; GO:0005634; GO:0001819; GO:0061136; GO:0006355; GO:0030317; GO:0007289; GO:0003712; GO:0006366,"DNA binding; Golgi apparatus; Golgi membrane; acrosome assembly; cellular response to organic cyclic compound; defense response to bacterium; male gonad development; negative regulation of gene expression; nucleus; positive regulation of cytokine production; regulation of proteasomal protein catabolic process; regulation of transcription, DNA-dependent; sperm motility; spermatid nucleus differentiation; transcription cofactor activity; transcription from RNA polymerase II promoter",PF12329;PF12325;,,,,,,,,,TMF1_HUMAN,Homo sapiens (Human),"acrosome assembly [GO:0001675]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; spermatid nucleus differentiation [GO:0007289]; sperm motility [GO:0030317]; transcription from RNA polymerase II promoter [GO:0006366]" comp135331_c0_seq3,1502,43.8083,0.24595477,11,5,,,,,,,,,6.00E-104,CHOYP_LOC580687.1.1,,,,,,,,, comp135340_c0_seq1,1163,39.8968,0.58872718,125,382,,3.00E-34,Q0V9J0,Transmembrane protein 69,Transmembrane protein 69,GO:0016021,integral to membrane,PF11911;,,,,,,,,,TMM69_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp135342_c0_seq1,2099,42.02,0.50003894,187,17,,0,Q8IZF0,Sodium leak channel non-selective protein (CanIon) (Voltage gated channel-like protein 1),Sodium leak channel non-selective protein (CanIon) (Voltage gated channel-like protein 1),GO:0016021; GO:0005886; GO:0005272; GO:0005244,integral to membrane; plasma membrane; sodium channel activity; voltage-gated ion channel activity,PF00520;,1.00E-171,CHOYP_LOC100883628.1.1,,,,,,,NALCN_HUMAN,Homo sapiens (Human),calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010] comp135350_c0_seq2,936,38.5684,1.31670085,19,70,,4.00E-24,Q95LU3,Fibrinogen C domain-containing protein 1,Fibrinogen C domain-containing protein 1,GO:0008061; GO:0016021; GO:0016020; GO:0046872,chitin binding; integral to membrane; membrane; metal ion binding,PF00147;,,,,,,,,,FBCD1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp135350_c0_seq3,226,44.6903,1.03269185,2,28,,5.00E-06,Q95LB0,Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI),GO:0007597; GO:0009986; GO:0042627; GO:0031012; GO:0008201; GO:0034364; GO:0060230; GO:0016525; GO:0030195; GO:0010596; GO:0001937; GO:0051918; GO:0033033; GO:0034392; GO:0005543; GO:0031639; GO:0051006; GO:0006641; GO:0034361,"blood coagulation, intrinsic pathway; cell surface; chylomicron; extracellular matrix; heparin binding; high-density lipoprotein particle; lipoprotein lipase activator activity; negative regulation of angiogenesis; negative regulation of blood coagulation; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; negative regulation of fibrinolysis; negative regulation of myeloid cell apoptotic process; negative regulation of smooth muscle cell apoptotic process; phospholipid binding; plasminogen activation; positive regulation of lipoprotein lipase activity; triglyceride metabolic process; very-low-density lipoprotein particle",PF00084;PF09014;,,,,,,,,,APOH_PANTR,Pan troglodytes (Chimpanzee),"blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]" comp135350_c0_seq7,360,44.1667,1.24183965,0,0,,9.00E-24,A2AV25,Fibrinogen C domain-containing protein 1,Fibrinogen C domain-containing protein 1,GO:0008061; GO:0016021; GO:0016020; GO:0046872,chitin binding; integral to membrane; membrane; metal ion binding,PF00147;,,,,,,,,,FBCD1_MOUSE,Mus musculus (Mouse), comp135351_c1_seq2,1482,36.9096,0.53831597,0,4,,8.00E-37,Q5RAS6,High affinity copper uptake protein 1 (Copper transporter 1) (Solute carrier family 31 member 1),High affinity copper uptake protein 1 (Copper transporter 1) (Solute carrier family 31 member 1),GO:0005375; GO:0016021; GO:0005886,copper ion transmembrane transporter activity; integral to membrane; plasma membrane,PF04145;,,,,,,,,,COPT1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp135351_c1_seq3,1606,36.7995,0.57586604,0,0,,1.00E-36,Q5RAS6,High affinity copper uptake protein 1 (Copper transporter 1) (Solute carrier family 31 member 1),High affinity copper uptake protein 1 (Copper transporter 1) (Solute carrier family 31 member 1),GO:0005375; GO:0016021; GO:0005886,copper ion transmembrane transporter activity; integral to membrane; plasma membrane,PF04145;,,,,,,,,,COPT1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp135354_c0_seq1,1070,43.6449,0.4448854,164,1107,,1.00E-82,Q9Y394,Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4),Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1),GO:0016491,oxidoreductase activity,PF00106;,1.00E-47,CHOYP_PHUM_PHUM490940.1.1,,,,,,,DHRS7_HUMAN,Homo sapiens (Human), comp135363_c0_seq1,1561,41.5119,0.37407589,1717,6398,,0,P07237,Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55),Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55),GO:0045454; GO:0009986; GO:0005788; GO:0005793; GO:0030198; GO:0005576; GO:0006662; GO:0042157; GO:0042470; GO:0018401; GO:0005886; GO:0004656; GO:0003756; GO:0015035,cell redox homeostasis; cell surface; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; extracellular matrix organization; extracellular region; glycerol ether metabolic process; lipoprotein metabolic process; melanosome; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; plasma membrane; procollagen-proline 4-dioxygenase activity; protein disulfide isomerase activity; protein disulfide oxidoreductase activity,PF00085;,5.00E-149,CHOYP_PDIA1.1.1,,,,,,,PDIA1_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; cellular response to hypoxia [GO:0071456]; lipoprotein biosynthetic process [GO:0042158]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; response to reactive oxygen species [GO:0000302] comp135365_c0_seq1,1445,37.9931,0.52378678,266,4456,,4.00E-147,Q64674,Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase),Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase),GO:0008295; GO:0004766,spermidine biosynthetic process; spermidine synthase activity,,2.00E-135,CHOYP_LOC100370747.1.1,,,,,,,SPEE_MOUSE,Mus musculus (Mouse),spermidine biosynthetic process [GO:0008295] comp135366_c0_seq1,370,35.1351,0.28531354,4,85,,2.00E-27,Q9SU94,Protein arginine N-methyltransferase 1.1 (AtPRMT11) (EC 2.1.1.-) (EC 2.1.1.125) (Arginine methyltransferase pam1) (Histone-arginine N-methyltransferase PRMT11),Protein arginine N-methyltransferase 1.1 (AtPRMT11) (EC 2.1.1.319) (Arginine methyltransferase pam1) (Histone-arginine N-methyltransferase PRMT11),GO:0005829; GO:0034969; GO:0008469; GO:0005634; GO:0016274; GO:0006355; GO:0006351,"cytosol; histone arginine methylation; histone-arginine N-methyltransferase activity; nucleus; protein-arginine N-methyltransferase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,5.00E-21,CHOYP_DDB_G0276237.1.1,,,,,,,ANM11_ARATH,Arabidopsis thaliana (Mouse-ear cress),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135366_c2_seq1,739,40.1894,0.47496878,30,165,,3.00E-18,Q9VQ62,Protein NPC2 homolog (Niemann Pick type C2 protein homolog),Protein NPC2 homolog (Niemann Pick type C2 protein homolog),GO:0045456; GO:0005615; GO:0030882; GO:0001530; GO:0070891; GO:0042834; GO:0061057; GO:0055092; GO:0015918; GO:0008039,ecdysteroid biosynthetic process; extracellular space; lipid antigen binding; lipopolysaccharide binding; lipoteichoic acid binding; peptidoglycan binding; peptidoglycan recognition protein signaling pathway; sterol homeostasis; sterol transport; synaptic target recognition,PF02221;,,,,,,,,,NPC2_DROME,Drosophila melanogaster (Fruit fly),ecdysteroid biosynthetic process [GO:0045456]; peptidoglycan recognition protein signaling pathway [GO:0061057]; sterol homeostasis [GO:0055092]; sterol transport [GO:0015918]; synaptic target recognition [GO:0008039] comp135366_c5_seq3,1322,38.6536,0.36876357,102,660,,3.00E-48,Q08A71,Probable protein arginine N-methyltransferase 6 (EC 2.1.1.-),Probable protein arginine N-methyltransferase 6 (EC 2.1.1.-),GO:0005737; GO:0008276,cytoplasm; protein methyltransferase activity,,,,,,,,,,ANM6_ARATH,Arabidopsis thaliana (Mouse-ear cress),"regulation of transcription, DNA-templated [GO:0006355]" comp135367_c0_seq5,3926,35.5833,0.40813063,0,0,,2.00E-10,A5DF78,Actin cytoskeleton-regulatory complex protein END3 (Endocytosis protein 3),Actin cytoskeleton-regulatory complex protein END3 (Endocytosis protein 3),GO:0030479; GO:0007015; GO:0005509; GO:0006897; GO:0010008; GO:0005886,actin cortical patch; actin filament organization; calcium ion binding; endocytosis; endosome membrane; plasma membrane,PF12763;PF12761;,,,,,,,,,END3_PICGU,Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii),actin filament organization [GO:0007015]; ascospore wall assembly [GO:0030476]; endocytosis [GO:0006897] comp135367_c0_seq6,3777,35.4249,0.42788189,0,0,,0,Q5RBP4,EH domain-containing protein 1,EH domain-containing protein 1,GO:0005524; GO:0005525; GO:0006184; GO:0003924; GO:0005509; GO:1990090; GO:0042632; GO:0031901; GO:0032456; GO:0030139; GO:0006897; GO:0006886; GO:0005811; GO:0034383; GO:0031175; GO:0048471; GO:0005886; GO:0031095; GO:0010886; GO:2001137; GO:1901741; GO:0051260; GO:0055038,ATP binding; GTP binding; GTP catabolic process; GTPase activity; calcium ion binding; cellular response to nerve growth factor stimulus; cholesterol homeostasis; early endosome membrane; endocytic recycling; endocytic vesicle; endocytosis; intracellular protein transport; lipid particle; low-density lipoprotein particle clearance; neuron projection development; perinuclear region of cytoplasm; plasma membrane; platelet dense tubular network membrane; positive regulation of cholesterol storage; positive regulation of endocytic recycling; positive regulation of myoblast fusion; protein homooligomerization; recycling endosome membrane,PF00350;PF12763;PF16880;,0,CHOYP_LOC100875390.1.1,,,,,,,EHD1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0042384]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; protein localization to cilium [GO:0061512] comp135368_c0_seq1,1035,35.2657,0.49813726,3,160,,3.00E-09,P41778,Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1),Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1),GO:0001077; GO:0030325; GO:0009952; GO:0001658; GO:0005737; GO:0035162; GO:0030326; GO:0048706; GO:0045665; GO:0043433; GO:0005634; GO:0009887; GO:0010971; GO:0008284; GO:0009954; GO:0030278; GO:0043565; GO:0007548; GO:0048536; GO:0006694; GO:0048538; GO:0005667,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; adrenal gland development; anterior/posterior pattern specification; branching involved in ureteric bud morphogenesis; cytoplasm; embryonic hemopoiesis; embryonic limb morphogenesis; embryonic skeletal system development; negative regulation of neuron differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; nucleus; organ morphogenesis; positive regulation of G2/M transition of mitotic cell cycle; positive regulation of cell proliferation; proximal/distal pattern formation; regulation of ossification; sequence-specific DNA binding; sex differentiation; spleen development; steroid biosynthetic process; thymus development; transcription factor complex,PF00046;PF03792;,3.00E-16,CHOYP_PBX4.1.2,,,,,,,PBX1_MOUSE,Mus musculus (Mouse),adrenal gland development [GO:0030325]; anterior/posterior pattern specification [GO:0009952]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic hemopoiesis [GO:0035162]; embryonic limb morphogenesis [GO:0030326]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; organ morphogenesis [GO:0009887]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of cell proliferation [GO:0042127]; regulation of ossification [GO:0030278]; sex differentiation [GO:0007548]; spleen development [GO:0048536]; steroid biosynthetic process [GO:0006694]; thymus development [GO:0048538]; urogenital system development [GO:0001655] comp135369_c0_seq1,569,44.1125,0.36190588,0,2,,5.00E-07,O60716,Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas)),Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas)),GO:0016055; GO:0034332; GO:0007155; GO:0034329; GO:0005913; GO:0016337; GO:0005911; GO:0005829; GO:0060690; GO:0030216; GO:0030027; GO:0030496; GO:0001738; GO:0090090; GO:0005634; GO:0005886; GO:0006355; GO:0007435; GO:0006351,"Wnt receptor signaling pathway; adherens junction organization; cell adhesion; cell junction assembly; cell-cell adherens junction; cell-cell adhesion; cell-cell junction; cytosol; epithelial cell differentiation involved in salivary gland development; keratinocyte differentiation; lamellipodium; midbody; morphogenesis of a polarized epithelium; negative regulation of canonical Wnt receptor signaling pathway; nucleus; plasma membrane; regulation of transcription, DNA-dependent; salivary gland morphogenesis; transcription, DNA-dependent",PF00514;,,,,,,,,,CTND1_HUMAN,Homo sapiens (Human),"adherens junction organization [GO:0034332]; brain development [GO:0007420]; cell adhesion [GO:0007155]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of transcription, DNA-templated [GO:0006355]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp135369_c0_seq2,1174,43.6968,0.49006771,39,123,,4.00E-10,Q68FH0,Plakophilin-4 (Armadillo-related protein),Plakophilin-4 (Armadillo-related protein),GO:0007155; GO:0044291; GO:0007043; GO:0030057; GO:0009898; GO:0030496; GO:0072686; GO:0048471; GO:0032321; GO:0032467; GO:0010628; GO:0051233; GO:0000922,cell adhesion; cell-cell contact zone; cell-cell junction assembly; desmosome; internal side of plasma membrane; midbody; mitotic spindle; perinuclear region of cytoplasm; positive regulation of Rho GTPase activity; positive regulation of cytokinesis; positive regulation of gene expression; spindle midzone; spindle pole,PF00514;,,,,,,,,,PKP4_MOUSE,Mus musculus (Mouse),cell-cell junction assembly [GO:0007043]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; single organismal cell-cell adhesion [GO:0016337] comp135372_c0_seq2,1606,39.8506,0.72370407,4,224,,1.00E-18,Q1EHB4,Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12),Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12),GO:0016324; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; integral to membrane; sodium ion transport; symporter activity,PF00474;,2.00E-27,CHOYP_BRAFLDRAFT_213839.1.2,,,,,,,SC5AC_HUMAN,Homo sapiens (Human),sodium ion transport [GO:0006814] comp135373_c0_seq1,401,41.3965,0.35196483,22,53,,2.00E-21,F4KCL7,"Outer envelope protein 64, mitochondrial (Mitochondrial outer membrane protein 64) (mtOM64) (Translocon at the outer membrane of chloroplasts 64-V) (AtTOC64-V)","Outer envelope protein 64, mitochondrial (Mitochondrial outer membrane protein 64) (mtOM64) (Translocon at the outer membrane of chloroplasts 64-V) (AtTOC64-V)",GO:0016884; GO:0016021; GO:0005741; GO:0005739; GO:0006626,"carbon-nitrogen ligase activity, with glutamine as amido-N-donor; integral to membrane; mitochondrial outer membrane; mitochondrion; protein targeting to mitochondrion",PF01425;,,,,,,,,,OE64M_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein targeting to mitochondrion [GO:0006626] comp135373_c1_seq1,1731,36.9728,0.37715169,74,408,,2.00E-141,P53042,Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PPT),Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PPT),GO:0005794; GO:0005737; GO:0016020; GO:0046872; GO:0043005; GO:0043025; GO:0005634; GO:0004721; GO:0043123; GO:0006470; GO:0051291; GO:0004871,Golgi apparatus; cytoplasm; membrane; metal ion binding; neuron projection; neuronal cell body; nucleus; phosphoprotein phosphatase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein dephosphorylation; protein heterooligomerization; signal transducer activity,PF00149;PF08321;PF00515;,9.00E-172,CHOYP_LOC100119577.1.1,,,,,,,PPP5_RAT,Rattus norvegicus (Rat),cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; histone dephosphorylation [GO:0016576]; negative regulation of cell death [GO:0060548]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; protein oligomerization [GO:0051259]; response to lead ion [GO:0010288]; response to morphine [GO:0043278] comp135377_c1_seq3,907,28.6659,0.69912428,28,216,,,,,,,,,,,2.00E-17,ruditapes_c17487,,,,,,, comp135377_c6_seq1,534,28.0899,1.28108756,33,43,,,,,,,,,,,6.00E-14,ruditapes_lrc17640,,,,,,, comp135379_c0_seq2,1107,39.4761,0.65952435,28,352,,6.00E-06,P18503,Short-chain collagen C4 (Fragment),Short-chain collagen C4 (Fragment),GO:0005581,collagen,PF01391;,,,,,,,,,CAS4_EPHMU,Ephydatia muelleri (Mueller's freshwater sponge), comp135380_c0_seq1,1293,40.0619,0.23176133,0,0,,0,Q922S4,"cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)","cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)",GO:0036004; GO:0005794; GO:0030424; GO:0030552; GO:0006198; GO:0019933; GO:0030553; GO:0046069; GO:0019934; GO:0004118; GO:0071321; GO:0035690; GO:0097011; GO:0071222; GO:0036006; GO:0071260; GO:0005829; GO:0030425; GO:0008144; GO:0005783; GO:0061028; GO:0016020; GO:0046872; GO:0005759; GO:0030818; GO:0033159; GO:0000122; GO:0043116; GO:0005634; GO:0048471; GO:0005886; GO:0010628; GO:0050729; GO:0043117; GO:0042734; GO:0042803; GO:0006626,"GAF domain binding; Golgi apparatus; axon; cAMP binding; cAMP catabolic process; cAMP-mediated signaling; cGMP binding; cGMP catabolic process; cGMP-mediated signaling; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; cellular response to cGMP; cellular response to drug; cellular response to granulocyte macrophage colony-stimulating factor stimulus; cellular response to lipopolysaccharide; cellular response to macrophage colony-stimulating factor stimulus; cellular response to mechanical stimulus; cytosol; dendrite; drug binding; endoplasmic reticulum; establishment of endothelial barrier; membrane; metal ion binding; mitochondrial matrix; negative regulation of cAMP biosynthetic process; negative regulation of protein import into nucleus, translocation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of vascular permeability; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of gene expression; positive regulation of inflammatory response; positive regulation of vascular permeability; presynaptic membrane; protein homodimerization activity; protein targeting to mitochondrion",PF01590;PF13185;PF00233;,9.00E-139,CHOYP_PDE2A.3.3,,,,,,,PDE2A_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; metabolic process [GO:0008152]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; protein targeting to mitochondrion [GO:0006626]; regulation of cGMP metabolic process [GO:0030823]; ventricular septum development [GO:0003281]" comp135380_c0_seq10,1454,40.9216,0.2304404,0,0,,0,Q922S4,"cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)","cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)",GO:0036004; GO:0005794; GO:0030424; GO:0030552; GO:0006198; GO:0019933; GO:0030553; GO:0046069; GO:0019934; GO:0004118; GO:0071321; GO:0035690; GO:0097011; GO:0071222; GO:0036006; GO:0071260; GO:0005829; GO:0030425; GO:0008144; GO:0005783; GO:0061028; GO:0016020; GO:0046872; GO:0005759; GO:0030818; GO:0033159; GO:0000122; GO:0043116; GO:0005634; GO:0048471; GO:0005886; GO:0010628; GO:0050729; GO:0043117; GO:0042734; GO:0042803; GO:0006626,"GAF domain binding; Golgi apparatus; axon; cAMP binding; cAMP catabolic process; cAMP-mediated signaling; cGMP binding; cGMP catabolic process; cGMP-mediated signaling; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; cellular response to cGMP; cellular response to drug; cellular response to granulocyte macrophage colony-stimulating factor stimulus; cellular response to lipopolysaccharide; cellular response to macrophage colony-stimulating factor stimulus; cellular response to mechanical stimulus; cytosol; dendrite; drug binding; endoplasmic reticulum; establishment of endothelial barrier; membrane; metal ion binding; mitochondrial matrix; negative regulation of cAMP biosynthetic process; negative regulation of protein import into nucleus, translocation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of vascular permeability; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of gene expression; positive regulation of inflammatory response; positive regulation of vascular permeability; presynaptic membrane; protein homodimerization activity; protein targeting to mitochondrion",PF01590;PF13185;PF00233;,,,,,,,,,PDE2A_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; metabolic process [GO:0008152]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; protein targeting to mitochondrion [GO:0006626]; regulation of cGMP metabolic process [GO:0030823]; ventricular septum development [GO:0003281]" comp135380_c0_seq11,1075,41.8605,0.27635554,0,0,,1.00E-43,O70628,"High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)","High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)",GO:0047555; GO:0005829; GO:0046872; GO:0007165,"3',5'-cyclic-GMP phosphodiesterase activity; cytosol; metal ion binding; signal transduction",PF00233;,2.00E-94,CHOYP_PDE2A.2.3,,,,,,,PDE9A_MOUSE,Mus musculus (Mouse),cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613] comp135380_c0_seq6,914,40.8096,0.28954065,0,0,,2.00E-17,Q86H13,"cAMP-specific 3',5'-cAMP phosphodiesterase 4 (EC 3.1.4.53) (Phosphodiesterase 4) (DdPDE4)","cAMP-specific 3',5'-cAMP phosphodiesterase 4 (EC 3.1.4.53) (Phosphodiesterase 4) (DdPDE4)",GO:0004115; GO:0030552; GO:0006198; GO:0005576; GO:0016021; GO:0046872; GO:0005886; GO:0031000; GO:0007165; GO:0030587,"3',5'-cyclic-AMP phosphodiesterase activity; cAMP binding; cAMP catabolic process; extracellular region; integral to membrane; metal ion binding; plasma membrane; response to caffeine; signal transduction; sorocarp development",PF00233;PF08499;,4.00E-91,CHOYP_PDE2A.3.3,,,,,,,PDE4_DICDI,Dictyostelium discoideum (Slime mold),cAMP catabolic process [GO:0006198]; response to caffeine [GO:0031000]; signal transduction [GO:0007165]; sorocarp development [GO:0030587] comp135381_c0_seq1,1258,39.2687,0.49735847,1826,143,,8.00E-142,Q80Y75,DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein),DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein),GO:0006457,protein folding,PF00226;PF01556;,8.00E-171,CHOYP_LOC100377412.1.1,0,ruditapes2_c577,2.00E-173,ES789943.p.cg.6,5,,DJB13_MOUSE,Mus musculus (Mouse),protein folding [GO:0006457] comp135385_c0_seq1,1506,37.3174,0.44119875,165,2710,,1.00E-159,Q5R5Z5,Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC),Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC),GO:0005794; GO:0031252; GO:0042995; GO:0005856; GO:0005768; GO:0005925; GO:0005886; GO:0030838; GO:1900026,Golgi apparatus; cell leading edge; cell projection; cytoskeleton; endosome; focal adhesion; plasma membrane; positive regulation of actin filament polymerization; positive regulation of substrate adhesion-dependent cell spreading,PF04045;,9.00E-114,CHOYP_TEN2.1.2,5.00E-102,ruditapes_c11970,,,,,ARPC2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026] comp135386_c1_seq1,2018,44.3013,0.42731752,143,102,,9.00E-44,Q13439,Golgin subfamily A member 4 (256 kDa golgin) (Golgin-245) (Protein 72.1) (Trans-Golgi p230),Golgin subfamily A member 4 (256 kDa golgin) (Golgin-245) (Protein 72.1) (Trans-Golgi p230),GO:0005794; GO:0000139; GO:0043001; GO:0000042; GO:0005802,Golgi apparatus; Golgi membrane; Golgi to plasma membrane protein transport; protein targeting to Golgi; trans-Golgi network,PF01465;,,,,,,,,,GOGA4_HUMAN,Homo sapiens (Human),Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; protein targeting to Golgi [GO:0000042]; vesicle-mediated transport [GO:0016192] comp135386_c1_seq3,587,46.678,0.46226549,0,0,,,,,,,,,3.00E-33,CHOYP_GOLGA4.1.3,,,,,,,,, comp135392_c0_seq1,1055,47.6777,0.49577509,87,236,,4.00E-164,Q3T0V9,Putative deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase),Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase),GO:0005737; GO:0046121; GO:0009264; GO:0046386; GO:0004139,cytoplasm; deoxyribonucleoside catabolic process; deoxyribonucleotide catabolic process; deoxyribose phosphate catabolic process; deoxyribose-phosphate aldolase activity,PF01791;,3.00E-137,CHOYP_BRAFLDRAFT_259692.1.1,,,,,,,DEOC_BOVIN,Bos taurus (Bovine),carbohydrate catabolic process [GO:0016052]; deoxyribonucleoside catabolic process [GO:0046121]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386] comp135393_c0_seq2,1048,33.5878,0.9263156,233,434,,,,,,,,,,,5.00E-12,ruditapes_c8961,,,,,,, comp135394_c0_seq1,340,43.5294,0.99799656,5,20,,7.00E-18,P63047,Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),GO:0005737; GO:0008202; GO:0008146; GO:0006790,cytoplasm; steroid metabolic process; sulfotransferase activity; sulfur compound metabolic process,PF00685;,,,,,,,,,ST4A1_RAT,Rattus norvegicus (Rat),steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790] comp135394_c2_seq1,781,37.1319,0.71774428,0,0,,2.00E-23,Q3T0Y3,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-),GO:0004062; GO:0005737; GO:0009812; GO:0008202; GO:0051923; GO:0042403; GO:0006805,aryl sulfotransferase activity; cytoplasm; flavonoid metabolic process; steroid metabolic process; sulfation; thyroid hormone metabolic process; xenobiotic metabolic process,PF00685;,1.00E-20,CHOYP_LOC100717261.1.1,,,,,,,ST1B1_BOVIN,Bos taurus (Bovine),epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp135394_c2_seq3,1086,35.7274,0.76361147,19,50,,9.00E-23,Q8JG30,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-),GO:0005737; GO:0008202; GO:0008146,cytoplasm; steroid metabolic process; sulfotransferase activity,PF00685;,2.00E-20,CHOYP_LOC100717261.1.1,3.00E-46,ruditapes_c20565,,,,,ST1B1_CHICK,Gallus gallus (Chicken),steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp135395_c0_seq1,2599,42.6318,0.56766314,17,0,,1.00E-30,Q11067,Probable protein disulfide-isomerase A6 (EC 5.3.4.1),Probable protein disulfide-isomerase A6 (EC 5.3.4.1),GO:0045454; GO:0005788; GO:0006662; GO:0003756; GO:0015035; GO:0006457,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding,PF00085;,,,,,,,,,PDIA6_CAEEL,Caenorhabditis elegans,apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; endoplasmic reticulum unfolded protein response [GO:0030968]; protein folding [GO:0006457] comp135395_c0_seq2,2471,43.0595,0.58519588,0,0,,0,Q8IXB1,DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr),DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr),GO:0001671; GO:0030433; GO:0045454; GO:0051087; GO:0034663; GO:0005788; GO:0006662; GO:0070059; GO:0051787; GO:0001933; GO:0016671; GO:0015035; GO:0034975,"ATPase activator activity; ER-associated protein catabolic process; cell redox homeostasis; chaperone binding; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; glycerol ether metabolic process; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; misfolded protein binding; negative regulation of protein phosphorylation; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; protein disulfide oxidoreductase activity; protein folding in endoplasmic reticulum",PF00226;PF00085;,,,,,,,,,DJC10_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATPase activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976] comp135395_c0_seq3,737,43.1479,0.68986105,6,0,,1.00E-79,Q5R5L3,DnaJ homolog subfamily C member 10 (EC 1.8.4.-),DnaJ homolog subfamily C member 10 (EC 1.8.4.-),GO:0030433; GO:0045454; GO:0005788; GO:0006662; GO:0016671; GO:0015035; GO:0034975,"ER-associated protein catabolic process; cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; protein disulfide oxidoreductase activity; protein folding in endoplasmic reticulum",PF00226;PF00085;,6.00E-68,CHOYP_NEMVEDRAFT_V1G163820.1.1,,,,,,,DJC10_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell redox homeostasis [GO:0045454]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein folding in endoplasmic reticulum [GO:0034975] comp135408_c0_seq1,1076,38.0112,0.67296381,98,76,,,,,,,,,1.00E-54,CHOYP_LOC100493179.3.15,,,,,,,,, comp135412_c0_seq1,1318,43.6267,0.4034826,124,512,,2.00E-155,Q7ZVK4,Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36),Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36),GO:0005768; GO:0032266; GO:0015031,endosome; phosphatidylinositol-3-phosphate binding; protein transport,PF04157;PF11605;,1.00E-79,CHOYP_VPS36.1.1,,,,,,,VPS36_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] comp135414_c0_seq15,523,47.4187,0.51389531,6,0,,4.00E-35,P49025,"Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)","Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)",GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0035556; GO:0046872; GO:0007091; GO:0000070; GO:0050774; GO:0045665; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; negative regulation of neuron differentiation; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,3.00E-45,CHOYP_CIT.1.2,,,,,,,CTRO_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283] comp135414_c0_seq5,1055,40,0.64185916,0,0,,1.00E-28,O14578,Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0048699; GO:0035556; GO:0046872; GO:0007091; GO:0007067; GO:0000070; GO:0050774; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; generation of neurons; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitosis; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,,,,,,,,,CTRO_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467] comp135414_c0_seq9,647,45.9042,0.59259401,0,0,,,,,,,,,4.00E-44,CHOYP_CIT.1.2,,,,,,,,, comp135418_c0_seq2,277,43.6823,0.07993204,253,0,,6.00E-06,P13730,Salivary glue protein Sgs-3,Salivary glue protein Sgs-3,,,,,,,,,,,,SGS3_DROER,Drosophila erecta (Fruit fly), comp135418_c0_seq4,215,44.6512,0.19789709,68,0,,1.00E-09,Q16994,Antho-RFamide neuropeptides type 2 [Cleaved into: Antho-RFamide],Antho-RFamide neuropeptides type 2 [Cleaved into: Antho-RFamide],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,,,,,,,,,FMR2_ANTEL,Anthopleura elegantissima (Sea anemone),neuropeptide signaling pathway [GO:0007218] comp135420_c0_seq1,931,46.2943,0.34768528,18,31,,8.00E-63,E1C2I2,Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L),Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L),GO:0005524; GO:0000086; GO:0051301; GO:0005813; GO:0032154; GO:0005737; GO:0007067; GO:0034048; GO:0005634; GO:0051721; GO:0004674; GO:0051726; GO:0006974,ATP binding; G2/M transition of mitotic cell cycle; cell division; centrosome; cleavage furrow; cytoplasm; mitosis; negative regulation of protein phosphatase type 2A activity; nucleus; protein phosphatase 2A binding; protein serine/threonine kinase activity; regulation of cell cycle; response to DNA damage stimulus,PF00069;,3.00E-29,CHOYP_GWL.1.1,,,,,,,GWL_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; negative regulation of protein phosphatase type 2A activity [GO:0034048]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell cycle [GO:0051726] comp135420_c0_seq2,741,46.5587,0.30591686,6,6,,5.00E-15,O43930,Putative serine/threonine-protein kinase PRKY (EC 2.7.11.1),Putative serine/threonine-protein kinase PRKY (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PRKY_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468] comp135423_c0_seq1,1189,34.3987,0.29239787,0,0,,1.00E-42,Q0V9J5,Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein),Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein),GO:0005634; GO:0003743,nucleus; translation initiation factor activity,PF01176;,4.00E-47,CHOYP_EIF1A.1.1,,,,,,,EIF1A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp135423_c0_seq2,1243,34.3524,0.28067344,4,20,,,,,,,,,5.00E-47,CHOYP_LOC100705082.1.1,,,,,,,,, comp135424_c0_seq1,1371,43.1072,0.4566093,0,0,,3.00E-19,Q8IVU3,Probable E3 ubiquitin-protein ligase HERC6 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 6),Probable E3 ubiquitin-protein ligase HERC6 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 6),GO:0005737; GO:0005829; GO:0005634; GO:0042787; GO:0004842,cytoplasm; cytosol; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC6_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp135424_c0_seq2,204,47.549,0.6132626,9,5,,,,,,,,,3.00E-27,CHOYP_HERC4.1.1,,,,,,,,, comp135424_c0_seq3,1372,42.6385,0.40280961,10,6,,9.00E-104,Q5GLZ8,Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),GO:0030154; GO:0005737; GO:0005829; GO:0005634; GO:0042787; GO:0007283; GO:0004842,cell differentiation; cytoplasm; cytosol; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC4_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp135424_c0_seq5,786,39.8219,0.38569041,0,0,,2.00E-48,Q5GLZ8,Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),GO:0030154; GO:0005737; GO:0005829; GO:0005634; GO:0042787; GO:0007283; GO:0004842,cell differentiation; cytoplasm; cytosol; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity,PF00632;PF00415;,9.00E-22,CHOYP_HERC4.1.1,,,,,,,HERC4_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp135432_c0_seq1,940,37.6596,0.52469884,227,1262,,1.00E-56,Q5RK00,"39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46)","39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46)",GO:0016787; GO:0005739; GO:0005840,hydrolase activity; mitochondrion; ribosome,PF11788;,,,3.00E-20,ruditapes_c10182,,,,,RM46_RAT,Rattus norvegicus (Rat), comp135434_c2_seq2,3448,42.2274,0.41649563,208,151,,0,Q6NU40,Chromosome transmission fidelity protein 18 homolog,Chromosome transmission fidelity protein 18 homolog,GO:0005524; GO:0003677; GO:0006260; GO:0007049; GO:0017111; GO:0005634,ATP binding; DNA binding; DNA replication; cell cycle; nucleoside-triphosphatase activity; nucleus,PF00004;PF08519;,9.00E-125,CHOYP_CTF18.1.1,,,,,,,CTF18_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; DNA replication [GO:0006260] comp135436_c0_seq1,1259,30.8975,0.4025776,804,2243,,,,,,,,,,,1.00E-13,ruditapes_c8844,,,,,,, comp135438_c0_seq1,1770,42.0339,0.42527829,0,0,,1.00E-60,A4Q9F3,Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),GO:0035085; GO:0005874; GO:0015630; GO:0018094; GO:0070737,"cilium axoneme; microtubule; microtubule cytoskeleton; protein polyglycylation; protein-glycine ligase activity, elongating",PF03133;,1.00E-63,CHOYP_LOC578816.1.1,,,,,,,TTL10_MOUSE,Mus musculus (Mouse),protein polyglycylation [GO:0018094] comp135438_c0_seq3,987,43.8703,0.46792436,0,0,,2.00E-07,P0CAZ0,Tubulin glycylase 3B (EC 6.3.2.-),Tubulin glycylase 3B (EC 6.3.2.-),GO:0035082; GO:0005929; GO:0042384; GO:0035085; GO:0005856; GO:0018094; GO:0070737,"axoneme assembly; cilium; cilium assembly; cilium axoneme; cytoskeleton; protein polyglycylation; protein-glycine ligase activity, elongating",PF03133;,5.00E-64,CHOYP_LOC578816.1.1,,,,,,,TTL3B_TETTS,Tetrahymena thermophila (strain SB210),axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; protein polyglycylation [GO:0018094] comp135438_c0_seq5,936,44.765,0.47421264,0,0,,6.00E-63,A4Q9F3,Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10),GO:0035085; GO:0005874; GO:0015630; GO:0018094; GO:0070737,"cilium axoneme; microtubule; microtubule cytoskeleton; protein polyglycylation; protein-glycine ligase activity, elongating",PF03133;,,,,,,,,,TTL10_MOUSE,Mus musculus (Mouse),protein polyglycylation [GO:0018094] comp135440_c0_seq1,969,30.8566,0.52248911,87,98,,,,,,,,,,,3.00E-14,ruditapes2_c2833,,,,,,, comp135440_c2_seq1,651,41.1674,0.36440953,0,0,,,,,,,,,6.00E-36,CHOYP_MET14.1.1,,,,,,,,, comp135440_c2_seq3,653,41.6539,0.35376293,0,0,,,,,,,,,2.00E-22,CHOYP_BRAFLDRAFT_121749.1.1,,,,,,,,, comp135440_c2_seq4,708,41.5254,0.36118259,5,38,,2.00E-25,Q554G3,COMM domain-containing protein 10,COMM domain-containing protein 10,,,PF07258;,3.00E-52,CHOYP_MET14.1.1,,,,,,,COMDA_DICDI,Dictyostelium discoideum (Slime mold), comp135440_c2_seq5,710,41.6901,0.32461371,0,0,,3.00E-54,Q9Y6G5,COMM domain-containing protein 10,COMM domain-containing protein 10,,,PF07258;,4.00E-32,CHOYP_BRAFLDRAFT_121749.1.1,,,,,,,COMDA_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135444_c0_seq2,1986,41.3897,0.41182089,0,0,,0,P97454,Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5),Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5),GO:0030509; GO:0001880; GO:0000979; GO:0001525; GO:0060348; GO:0060048; GO:0051216; GO:0071773; GO:0071407; GO:0005737; GO:0009880; GO:0030218; GO:0007281; GO:0046872; GO:0005634; GO:0002051; GO:0045669; GO:1901522; GO:0006468; GO:0003700; GO:0005667; GO:0006351; GO:0007179; GO:0001657,"BMP signaling pathway; Mullerian duct regression; RNA polymerase II core promoter sequence-specific DNA binding; angiogenesis; bone development; cardiac muscle contraction; cartilage development; cellular response to BMP stimulus; cellular response to organic cyclic compound; cytoplasm; embryonic pattern specification; erythrocyte differentiation; germ cell development; metal ion binding; nucleus; osteoblast fate commitment; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; protein phosphorylation; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; ureteric bud development",PF03165;PF03166;,,,,,,,,,SMAD5_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle contraction [GO:0060048]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; erythrocyte differentiation [GO:0030218]; germ cell development [GO:0007281]; Mullerian duct regression [GO:0001880]; osteoblast fate commitment [GO:0002051]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]" comp135444_c0_seq3,2149,40.9027,0.42299179,10,18,,0,P97454,Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5),Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5),GO:0030509; GO:0001880; GO:0000979; GO:0001525; GO:0060348; GO:0060048; GO:0051216; GO:0071773; GO:0071407; GO:0005737; GO:0009880; GO:0030218; GO:0007281; GO:0046872; GO:0005634; GO:0002051; GO:0045669; GO:1901522; GO:0006468; GO:0003700; GO:0005667; GO:0006351; GO:0007179; GO:0001657,"BMP signaling pathway; Mullerian duct regression; RNA polymerase II core promoter sequence-specific DNA binding; angiogenesis; bone development; cardiac muscle contraction; cartilage development; cellular response to BMP stimulus; cellular response to organic cyclic compound; cytoplasm; embryonic pattern specification; erythrocyte differentiation; germ cell development; metal ion binding; nucleus; osteoblast fate commitment; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; protein phosphorylation; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; ureteric bud development",PF03165;PF03166;,0,CHOYP_SMAD1.2.2,,,,,,,SMAD5_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle contraction [GO:0060048]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; erythrocyte differentiation [GO:0030218]; germ cell development [GO:0007281]; Mullerian duct regression [GO:0001880]; osteoblast fate commitment [GO:0002051]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]" comp135445_c2_seq1,1599,30.2689,0.21952399,171,369,,,,,,,,,,,7.00E-12,ruditapes_c6584,,,,,,, comp135446_c0_seq1,904,42.8097,0.68971233,0,0,,9.00E-108,P13623,Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,1.00E-167,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,NFIX_MESAU,Mesocricetus auratus (Golden hamster),"DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq10,2364,47.8003,0.52759668,0,0,,1.00E-102,Q02780,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIA_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074] comp135446_c0_seq11,3004,45.972,0.51746157,0,0,,1.00E-101,P13623,Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIX_MESAU,Mesocricetus auratus (Golden hamster),"DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq12,934,42.7195,0.67052633,0,0,,5.00E-103,P14057,Nuclear factor 1 (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I) (NF-I) (TGGCA-binding protein) (Fragment),Nuclear factor 1 (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I) (NF-I) (TGGCA-binding protein) (Fragment),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF03165;PF10524;,,,,,,,,,NFIL_PIG,Sus scrofa (Pig),"DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq13,3119,44.5656,0.50412653,0,0,,3.00E-101,Q12857,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045944; GO:0014070; GO:0003700; GO:0006351; GO:0019079,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to organic cyclic compound; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; viral genome replication",PF00859;PF03165;PF10524;,,,,,,,,,NFIA_HUMAN,Homo sapiens (Human),"DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; synapse maturation [GO:0060074]; viral genome replication [GO:0019079]" comp135446_c0_seq14,781,46.3508,0.67362055,0,0,,5.00E-102,P17924,Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein),Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein),GO:0060486; GO:0003677; GO:0006260; GO:0001077; GO:0060509; GO:0060510; GO:0021960; GO:0044300; GO:0002062; GO:0071679; GO:0010001; GO:0061141; GO:2000795; GO:2000791; GO:0005634; GO:0045944; GO:0021740; GO:0000981,Clara cell differentiation; DNA binding; DNA replication; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; Type I pneumocyte differentiation; Type II pneumocyte differentiation; anterior commissure morphogenesis; cerebellar mossy fiber; chondrocyte differentiation; commissural neuron axon guidance; glial cell differentiation; lung ciliated cell differentiation; negative regulation of epithelial cell proliferation involved in lung morphogenesis; negative regulation of mesenchymal cell proliferation involved in lung development; nucleus; positive regulation of transcription from RNA polymerase II promoter; principal sensory nucleus of trigeminal nerve development; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF00859;PF03165;PF10524;,7.00E-163,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,NFIB_CHICK,Gallus gallus (Chicken),"anterior commissure morphogenesis [GO:0021960]; chondrocyte differentiation [GO:0002062]; Clara cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glial cell differentiation [GO:0010001]; lung ciliated cell differentiation [GO:0061141]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; transcription, DNA-templated [GO:0006351]; Type II pneumocyte differentiation [GO:0060510]; Type I pneumocyte differentiation [GO:0060509]" comp135446_c0_seq15,1511,46.3269,0.53095547,0,0,,4.00E-108,P13623,Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,2.00E-180,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,NFIX_MESAU,Mesocricetus auratus (Golden hamster),"DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq16,2141,49.6497,0.51833042,0,0,,8.00E-106,P09414,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045893; GO:0014070; GO:0003700; GO:0006351,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription, DNA-dependent; response to organic cyclic compound; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIA_RAT,Rattus norvegicus (Rat),"DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to organic cyclic compound [GO:0014070]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq18,3049,44.6048,0.49488248,0,0,,4.00E-99,P08651,Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0000122; GO:0005634; GO:0042475; GO:0045944; GO:0003700; GO:0006366,DNA binding; DNA replication; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis of dentin-containing tooth; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,PF00859;PF03165;PF10524;,,,,,,,,,NFIC_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp135446_c0_seq20,1541,46.2038,0.5234466,0,0,,1.00E-102,P70255,Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0000122; GO:0005634; GO:0042475; GO:0045944; GO:0003700; GO:0006351,"DNA binding; DNA replication; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis of dentin-containing tooth; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIC_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp135446_c0_seq22,3197,44.9171,0.52762039,0,0,,,,,,,,,2.00E-177,CHOYP_NFIA.1.1,,,,,,,,, comp135446_c0_seq24,2442,48.1572,0.55277916,0,0,,2.00E-106,Q02780,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,1.00E-177,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,NFIA_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074] comp135446_c0_seq26,2294,47.9512,0.51714721,0,0,,8.00E-100,P21999,Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIC_PIG,Sus scrofa (Pig),"DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq27,3157,44.9161,0.51532307,0,0,,1.00E-98,P08651,Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0000122; GO:0005634; GO:0042475; GO:0045944; GO:0003700; GO:0006366,DNA binding; DNA replication; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis of dentin-containing tooth; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,PF00859;PF03165;PF10524;,,,,,,,,,NFIC_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp135446_c0_seq28,1581,46.1733,0.54627094,0,0,,,,,,,,,9.00E-178,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,,, comp135446_c0_seq29,2896,45.6837,0.49721734,0,0,,4.00E-104,P13623,Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIX_MESAU,Mesocricetus auratus (Golden hamster),"DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq3,3034,45.913,0.51360002,0,0,,3.00E-101,P09414,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045893; GO:0014070; GO:0003700; GO:0006351,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription, DNA-dependent; response to organic cyclic compound; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIA_RAT,Rattus norvegicus (Rat),"DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to organic cyclic compound [GO:0014070]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq32,2334,47.9006,0.53228866,0,0,,1.00E-105,Q02780,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIA_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074] comp135446_c0_seq33,3019,44.6505,0.49881084,0,0,,2.00E-105,P13623,Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,3.00E-180,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,NFIX_MESAU,Mesocricetus auratus (Golden hamster),"DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]" comp135446_c0_seq37,2372,48.3137,0.54336055,0,0,,2.00E-106,Q02780,Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0030054; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; DNA replication; cell junction; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,,,,,,,,,NFIA_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074] comp135446_c0_seq38,974,42.8131,0.70346394,0,0,,,,,,,,,2.00E-164,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,,, comp135446_c0_seq8,3127,44.9632,0.51920906,0,0,,3.00E-99,P08651,Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0000122; GO:0005634; GO:0042475; GO:0045944; GO:0003700; GO:0006366,DNA binding; DNA replication; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis of dentin-containing tooth; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,PF00859;PF03165;PF10524;,,,,,,,,,NFIC_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp135446_c0_seq9,2264,48.0565,0.52183292,0,0,,1.00E-107,P13623,Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein),GO:0003677; GO:0006260; GO:0005634; GO:0003700; GO:0006351,"DNA binding; DNA replication; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00859;PF03165;PF10524;,2.00E-180,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,NFIX_MESAU,Mesocricetus auratus (Golden hamster),"DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]" comp135447_c1_seq11,2454,40.1793,0.70713192,6,3,,4.00E-34,Q98925,Interferon regulatory factor 2 (IRF-2),Interferon regulatory factor 2 (IRF-2),GO:0005925; GO:0005634; GO:0000975; GO:0003700; GO:0006351,"focal adhesion; nucleus; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;,,,,,,,,,IRF2_CHICK,Gallus gallus (Chicken),cell proliferation [GO:0008283] comp135447_c1_seq12,2467,40.2513,0.70087479,0,0,,6.00E-14,P56477,Interferon regulatory factor 5 (IRF-5),Interferon regulatory factor 5 (IRF-5),GO:0005737; GO:0051607; GO:0045087; GO:0005634; GO:0000975; GO:0003700; GO:0006351,"cytoplasm; defense response to virus; innate immune response; nucleus; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;PF10401;,,,,,,,,,IRF5_MOUSE,Mus musculus (Mouse),"cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494]; transcription, DNA-templated [GO:0006351]" comp135447_c1_seq3,2423,40.0743,0.71992884,0,0,,4.00E-34,Q98925,Interferon regulatory factor 2 (IRF-2),Interferon regulatory factor 2 (IRF-2),GO:0005925; GO:0005634; GO:0000975; GO:0003700; GO:0006351,"focal adhesion; nucleus; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;,,,,,,,,,IRF2_CHICK,Gallus gallus (Chicken),cell proliferation [GO:0008283] comp135447_c1_seq4,2436,40.1888,0.71200813,0,0,,6.00E-14,P56477,Interferon regulatory factor 5 (IRF-5),Interferon regulatory factor 5 (IRF-5),GO:0005737; GO:0051607; GO:0045087; GO:0005634; GO:0000975; GO:0003700; GO:0006351,"cytoplasm; defense response to virus; innate immune response; nucleus; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;PF10401;,,,,,,,,,IRF5_MOUSE,Mus musculus (Mouse),"cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494]; transcription, DNA-templated [GO:0006351]" comp135449_c0_seq1,1031,40.7371,0.51399346,30,203,,5.00E-21,A6M0L7,UPF0249 protein Cbei_4037,Carbohydrate deacetylase (EC 3.5.1.-),GO:0005975; GO:0016810,"carbohydrate metabolic process; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",PF04794;,,,,,,,,,Y4037_CLOB8,Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum),polysaccharide catabolic process [GO:0000272] comp135449_c0_seq2,1049,40.6101,0.55602933,31,448,,7.00E-68,A2BIR6,UPF0249 protein ydjC homolog,Carbohydrate deacetylase (EC 3.5.1.-),GO:0005975; GO:0016810,"carbohydrate metabolic process; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",PF04794;,,,,,,,,,YDJC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate metabolic process [GO:0005975] comp135449_c0_seq3,1020,41.1765,0.5316329,6,29,,3.00E-68,Q14BV6,UPF0249 protein ydjC homolog,Carbohydrate deacetylase (EC 3.5.1.-),GO:0005975; GO:0016810,"carbohydrate metabolic process; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",PF04794;,,,,,,,,,YDJC_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975] comp135450_c0_seq1,1589,39.8364,0.61423687,319,1924,,1.00E-16,Q9D361,U11/U12 small nuclear ribonucleoprotein 48 kDa protein (U11/U12 snRNP 48 kDa protein),U11/U12 small nuclear ribonucleoprotein 48 kDa protein (U11/U12 snRNP 48 kDa protein),GO:0008380; GO:0005689; GO:0005737; GO:0006397; GO:0046872,RNA splicing; U12-type spliceosomal complex; cytoplasm; mRNA processing; metal ion binding,PF05253;,,,,,,,,,SNR48_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp135451_c0_seq1,2566,40.608,0.43456759,5,0,,1.00E-46,Q8NDI1,EH domain-binding protein 1,EH domain-binding protein 1,GO:0005737; GO:0016020,cytoplasm; membrane,PF00307;PF12130;PF10358;,,,,,,,,,EHBP1_HUMAN,Homo sapiens (Human), comp135451_c0_seq2,1706,39.3904,0.42800742,1,0,,9.00E-14,Q8CJ19,Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),GO:0071949; GO:0003779; GO:0030042; GO:0005737; GO:0005856; GO:0006887; GO:0016709; GO:0008270,"FAD binding; actin binding; actin filament depolymerization; cytoplasm; cytoskeleton; exocytosis; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; zinc ion binding",PF00307;PF12130;PF01494;PF00412;,,,,,,,,,MICA3_MOUSE,Mus musculus (Mouse),actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114] comp135451_c0_seq3,1575,42.9841,0.59190186,100,36,,1.00E-79,Q69ZW3,EH domain-binding protein 1,EH domain-binding protein 1,GO:0005737; GO:0016020,cytoplasm; membrane,PF00307;PF12130;PF10358;,3.00E-70,CHOYP_EHBP1.2.2,,,,,,,EHBP1_MOUSE,Mus musculus (Mouse), comp135451_c0_seq5,1292,37.9257,0.44087588,0,11,,,,,,,,,1.00E-53,CHOYP_EHBP1.2.2,,,,,,,,, comp135452_c0_seq1,2471,43.9093,0.38843236,0,0,,2.00E-133,P55265,Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP),Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP),GO:0003677; GO:0003723; GO:0006382; GO:0005737; GO:0051607; GO:0003726; GO:0010467; GO:0031047; GO:0016556; GO:0006397; GO:0046872; GO:0043066; GO:0044387; GO:0005730; GO:0005654; GO:0005634; GO:0045070; GO:0006611; GO:0006606; GO:0035455; GO:0009615; GO:0044530; GO:0060337,DNA binding; RNA binding; adenosine to inosine editing; cytoplasm; defense response to virus; double-stranded RNA adenosine deaminase activity; gene expression; gene silencing by RNA; mRNA modification; mRNA processing; metal ion binding; negative regulation of apoptotic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; nucleoplasm; nucleus; positive regulation of viral genome replication; protein export from nucleus; protein import into nucleus; response to interferon-alpha; response to virus; supraspliceosomal complex; type I interferon-mediated signaling pathway,PF02137;PF00035;PF02295;,,,,,,,,,DSRAD_HUMAN,Homo sapiens (Human),adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337] comp135452_c0_seq2,2801,43.2346,0.38323299,14,14,,,,,,,,,1.00E-83,CHOYP_LOC584058.1.1,,,,,,,,, comp135456_c1_seq1,1918,42.5965,0.2760887,78,78,,4.00E-75,E7FCN8,Protein inturned (Inturned planar cell polarity effector homolog),Protein inturned (Inturned planar cell polarity effector homolog),GO:0009986; GO:0042384; GO:0005737; GO:0060173; GO:0007399; GO:0008589,cell surface; cilium assembly; cytoplasm; limb development; nervous system development; regulation of smoothened signaling pathway,,,,,,,,,,INTU_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; limb development [GO:0060173]; nervous system development [GO:0007399]; regulation of smoothened signaling pathway [GO:0008589] comp135456_c3_seq2,923,38.6782,0.32057062,48,87,,7.00E-21,Q2I0E5,Protein inturned (Inturned planar cell polarity effector homolog) (Xint),Protein inturned (Inturned planar cell polarity effector homolog) (Xint),GO:0045177; GO:0009986; GO:0042384; GO:0005737; GO:0001736; GO:0032053; GO:0007275; GO:0005886; GO:0008104; GO:0008589,apical part of cell; cell surface; cilium assembly; cytoplasm; establishment of planar polarity; microtubule basal body organization; multicellular organismal development; plasma membrane; protein localization; regulation of smoothened signaling pathway,,,,,,,,,,INTU_XENLA,Xenopus laevis (African clawed frog),ciliary basal body organization [GO:0032053]; cilium assembly [GO:0042384]; establishment of planar polarity [GO:0001736]; multicellular organism development [GO:0007275]; protein localization [GO:0008104]; regulation of smoothened signaling pathway [GO:0008589] comp135458_c0_seq1,1188,38.2997,0.41520225,20,90,,3.00E-130,Q5F495,MOB-like protein phocein (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3),MOB-like protein phocein (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3),GO:0032580; GO:0046872; GO:0006810,Golgi cisterna membrane; metal ion binding; transport,PF03637;,3.00E-131,CHOYP_PHOCN.1.1,,,,,,,PHOCN_CHICK,Gallus gallus (Chicken),transport [GO:0006810] comp135458_c0_seq2,1104,37.7717,0.35676428,0,8,,5.00E-10,Q54CR8,MOB kinase activator-like 1 homolog B (Mps one binder kinase activator-like 1 homolog B),MOB kinase activator-like 1 homolog B (Mps one binder kinase activator-like 1 homolog B),GO:0046872,metal ion binding,PF03637;,,,,,,,,,MOB1B_DICDI,Dictyostelium discoideum (Slime mold), comp135459_c0_seq1,2704,33.8018,0.9589994,674,970,,2.00E-53,P22680,Cholesterol 7-alpha-monooxygenase (EC 1.14.13.17) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cytochrome P450 7A1),Cholesterol 7-alpha-monooxygenase (EC 1.14.14.23) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cytochrome P450 7A1),GO:0006699; GO:0044255; GO:0071397; GO:0071333; GO:0008123; GO:0006707; GO:0042632; GO:0005789; GO:0020037; GO:0005506; GO:0070857; GO:0006805,bile acid biosynthetic process; cellular lipid metabolic process; cellular response to cholesterol; cellular response to glucose stimulus; cholesterol 7-alpha-monooxygenase activity; cholesterol catabolic process; cholesterol homeostasis; endoplasmic reticulum membrane; heme binding; iron ion binding; regulation of bile acid biosynthetic process; xenobiotic metabolic process,PF00067;,2.00E-29,CHOYP_LOC100565509.1.1,,,,,,,CP7A1_HUMAN,Homo sapiens (Human),bile acid biosynthetic process [GO:0006699]; cellular response to cholesterol [GO:0071397]; cellular response to glucose stimulus [GO:0071333]; cholesterol catabolic process [GO:0006707]; cholesterol homeostasis [GO:0042632]; regulation of bile acid biosynthetic process [GO:0070857]; sterol metabolic process [GO:0016125] comp135462_c2_seq1,2389,40.226,0.72735981,20,8,,6.00E-48,O54990,Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133),Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133),GO:0016324; GO:0005903; GO:0060219; GO:0009986; GO:0005615; GO:0005887; GO:0031528; GO:0001750; GO:0071914; GO:0010842; GO:0032420,apical plasma membrane; brush border; camera-type eye photoreceptor cell differentiation; cell surface; extracellular space; integral to plasma membrane; microvillus membrane; photoreceptor outer segment; prominosome; retina layer formation; stereocilium,PF05478;,,,,,,,,,PROM1_MOUSE,Mus musculus (Mouse),camera-type eye photoreceptor cell differentiation [GO:0060219]; glomerular parietal epithelial cell differentiation [GO:0072139]; glomerular visceral epithelial cell differentiation [GO:0072112]; photoreceptor cell maintenance [GO:0045494]; positive regulation of nephron tubule epithelial cell differentiation [GO:2000768]; retina layer formation [GO:0010842]; retina morphogenesis in camera-type eye [GO:0060042] comp135464_c0_seq1,1612,38.3375,0.57638043,0,11,,,,,,,,,,,1.00E-16,ruditapes_c27301,,,,,,, comp135464_c0_seq2,2600,40.8077,0.51615116,158,438,,5.00E-86,Q66HG8,Protein Red (Cytokine IK) (IK factor),Protein Red (Cytokine IK) (IK factor),GO:0005634,nucleus,PF07807;PF07808;,0,CHOYP_RED.2.2,8.00E-46,ruditapes_c24366,,,,,RED_RAT,Rattus norvegicus (Rat), comp135469_c0_seq1,1448,39.9171,0.49525786,76,134,,5.00E-82,Q6DJ95,"Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)","Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)",GO:0005524; GO:0004817; GO:0006423; GO:0005829; GO:0046872; GO:0005759,ATP binding; cysteine-tRNA ligase activity; cysteinyl-tRNA aminoacylation; cytosol; metal ion binding; mitochondrial matrix,PF09190;PF01406;,,,,,,,,,SYCM_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cysteinyl-tRNA aminoacylation [GO:0006423] comp135471_c0_seq2,3168,47.9482,0.52418514,130,143,,2.00E-34,Q6DDH6,Histone deacetylase complex subunit SAP130-A (130 kDa Sin3-associated polypeptide A) (Sin3-associated polypeptide p130 A),Histone deacetylase complex subunit SAP130-A (130 kDa Sin3-associated polypeptide A) (Sin3-associated polypeptide p130 A),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16014;,1.00E-58,CHOYP_LOC100370716.1.1,7.00E-41,ruditapes_c36522,,,,,SP13A_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135472_c0_seq1,1024,38.9648,0.47126482,478,1412,,3.00E-43,Q9R0A8,HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5),HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5),GO:0070652; GO:0051301; GO:0051297; GO:0005737; GO:0005874; GO:0005815; GO:0007067; GO:0051225; GO:0000922,HAUS complex; cell division; centrosome organization; cytoplasm; microtubule; microtubule organizing center; mitosis; spindle assembly; spindle pole,,,,,,,,,,HAUS1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp135473_c1_seq1,348,40.5172,0.4921475,0,0,,,,,,,,,,,6.00E-11,ruditapes_c3458,,,,,,, comp135473_c1_seq2,948,41.0338,0.57976584,26,68,,1.00E-08,Q4QY64,ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein),ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein),GO:0005524; GO:0017111; GO:0005634; GO:0006974,ATP binding; nucleoside-triphosphatase activity; nucleus; response to DNA damage stimulus,PF00004;,,,4.00E-12,ruditapes_c1831,,,,,ATAD5_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; immunoglobulin production [GO:0002377]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990] comp135476_c0_seq4,1650,49.7576,0.93294058,0,0,,1.00E-24,Q3BAI2,Uncharacterized protein ORF91,Uncharacterized protein ORF91,GO:0009507,chloroplast,,0,CHOYP_contig_009415,,,,,,,YCX91_PHAAO,Phalaenopsis aphrodite subsp. formosana (Moth orchid), comp135476_c0_seq6,1804,48.5588,0.91590136,0,96,,,,,,,,,2.00E-59,CHOYP_ARALYDRAFT_497139.1.1,,,,,,,,, comp135477_c1_seq1,1381,36.5677,1.00088219,61,215,,9.00E-30,Q924Z4,Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3),Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3),GO:0046513; GO:0005789; GO:0016021; GO:0031965; GO:0043565; GO:0003700; GO:0050291,ceramide biosynthetic process; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sphingosine N-acyltransferase activity,PF00046;PF03798;,,,,,,,,,CERS2_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148] comp135481_c0_seq1,1596,42.4812,0.4899438,43,109,,1.00E-158,Q9Y253,DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein),DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein),GO:0006260; GO:0000731; GO:0003887; GO:0005737; GO:0003684; GO:0046872; GO:0005654; GO:0006301; GO:0006290; GO:0006282; GO:0010225,DNA replication; DNA synthesis involved in DNA repair; DNA-directed DNA polymerase activity; cytoplasm; damaged DNA binding; metal ion binding; nucleoplasm; postreplication repair; pyrimidine dimer repair; regulation of DNA repair; response to UV-C,PF00817;PF11799;,8.00E-71,CHOYP_POLH.1.1,,,,,,,POLH_HUMAN,Homo sapiens (Human),cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to UV-C [GO:0010225]; translesion synthesis [GO:0019985] comp135481_c0_seq2,1058,44.4234,0.53320327,0,0,,2.00E-29,Q9JRG1,DNA polymerase IV (Pol IV) (EC 2.7.7.7),DNA polymerase IV (Pol IV) (EC 2.7.7.7),GO:0006281; GO:0006261; GO:0003887; GO:0005737; GO:0003684; GO:0000287,DNA repair; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; cytoplasm; damaged DNA binding; magnesium ion binding,PF00817;PF11799;PF11798;,,,,,,,,,DPO4_NEIMA,Neisseria meningitidis serogroup A / serotype 4A (strain Z2491),DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281] comp135482_c0_seq2,1424,31.6713,0.36734105,89,112,,2.00E-17,P0C2B8,"39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55)","39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF09776;,,,,,,,,,RM55_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; translation [GO:0006412] comp135488_c0_seq1,794,43.199,0.57292472,8,44,,6.00E-17,O54786,DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD),DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD),GO:0006309; GO:0005737; GO:1900118; GO:0000790; GO:0005634; GO:0043065; GO:0070242,apoptotic DNA fragmentation; cytoplasm; negative regulation of execution phase of apoptosis; nuclear chromatin; nucleus; positive regulation of apoptotic process; thymocyte apoptotic process,PF02017;PF09033;,,,,,,,,,DFFA_MOUSE,Mus musculus (Mouse),negative regulation of apoptotic DNA fragmentation [GO:1902511]; negative regulation of execution phase of apoptosis [GO:1900118]; positive regulation of apoptotic process [GO:0043065]; thymocyte apoptotic process [GO:0070242] comp135490_c0_seq1,835,35.0898,1.0350491,7,75,,3.00E-12,Q67EQ1,C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin),C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin),GO:0030246; GO:0006955; GO:0016021; GO:0050715; GO:0004872,carbohydrate binding; immune response; integral to membrane; positive regulation of cytokine secretion; receptor activity,PF00059;,,,,,,,,,CLC4E_RAT,Rattus norvegicus (Rat),immune response [GO:0006955]; positive regulation of cytokine secretion [GO:0050715] comp135490_c0_seq2,846,34.6336,1.08281401,26,113,,8.00E-16,Q8BNX1,C-type lectin domain family 4 member G,C-type lectin domain family 4 member G,GO:0030246; GO:0016021,carbohydrate binding; integral to membrane,PF00059;,,,,,,,,,CLC4G_MOUSE,Mus musculus (Mouse),negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell proliferation [GO:0042130] comp135490_c0_seq3,453,41.7219,0.78655962,2,52,,7.00E-17,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp135491_c0_seq1,1397,43.3071,0.71809873,0,0,,1.00E-83,O95718,Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2),Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2),GO:0000980; GO:0004879; GO:0005654; GO:0045944; GO:0019827; GO:0005496; GO:0003707; GO:0003713; GO:0008134; GO:0006367; GO:0001834; GO:0001831; GO:0008270,RNA polymerase II distal enhancer sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance; steroid binding; steroid hormone receptor activity; transcription coactivator activity; transcription factor binding; transcription initiation from RNA polymerase II promoter; trophectodermal cell proliferation; trophectodermal cellular morphogenesis; zinc ion binding,PF00104;PF00105;,,,,,,,,,ERR2_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp135491_c0_seq10,1438,43.7413,0.71367443,0,0,,2.00E-83,O95718,Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2),Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2),GO:0000980; GO:0004879; GO:0005654; GO:0045944; GO:0019827; GO:0005496; GO:0003707; GO:0003713; GO:0008134; GO:0006367; GO:0001834; GO:0001831; GO:0008270,RNA polymerase II distal enhancer sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance; steroid binding; steroid hormone receptor activity; transcription coactivator activity; transcription factor binding; transcription initiation from RNA polymerase II promoter; trophectodermal cell proliferation; trophectodermal cellular morphogenesis; zinc ion binding,PF00104;PF00105;,,,,,,,,,ERR2_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp135491_c0_seq12,1401,42.541,0.74302892,0,0,,1.00E-21,P18515,Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2) (Fragment),Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2) (Fragment),GO:0005634; GO:0003708; GO:0043565; GO:0043401; GO:0003707; GO:0008270,nucleus; retinoic acid receptor activity; sequence-specific DNA binding; steroid hormone mediated signaling pathway; steroid hormone receptor activity; zinc ion binding,PF00105;,1.00E-55,CHOYP_ERR3.1.1,,,,,,,RARB_NOTVI,Notophthalmus viridescens (Eastern newt) (Triturus viridescens),"steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]" comp135491_c0_seq13,1419,42.4947,0.73508716,0,0,,1.00E-32,P57781,Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2),Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2),GO:0030284; GO:0030520; GO:0005634; GO:0043565; GO:0003700; GO:0005496; GO:0006351; GO:0008270,"estrogen receptor activity; intracellular estrogen receptor signaling pathway; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; transcription, DNA-dependent; zinc ion binding",PF12497;PF00104;PF00105;,,,,,,,,,ESR2_MICUN,Micropogonias undulatus (Atlantic croaker),"intracellular estrogen receptor signaling pathway [GO:0030520]; transcription, DNA-templated [GO:0006351]" comp135491_c0_seq3,1442,42.9958,0.73579581,0,0,,,,,,,,,1.00E-55,CHOYP_ERR3.1.1,,,,,,,,, comp135491_c0_seq5,597,45.2261,0.65986392,0,0,,3.00E-17,Q9IAC6,Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2) (Fragment),Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2) (Fragment),GO:0005737; GO:0005634; GO:0043565; GO:0003700; GO:0005496; GO:0003707; GO:0006351; GO:0008270,"cytoplasm; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,MCR_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),"negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; positive regulation of gene expression [GO:0010628]; response to 11-deoxycorticosterone [GO:1903496]; response to cortisol [GO:0051414]; transcription, DNA-templated [GO:0006351]" comp135491_c0_seq6,1456,43.6813,0.70684072,0,0,,3.00E-83,Q5RAM2,Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3),Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3),GO:0005634; GO:0003708; GO:0043565; GO:0005496; GO:0003707; GO:0008270,nucleus; retinoic acid receptor activity; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,ERR3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135491_c0_seq8,1415,43.2509,0.71078299,0,0,,2.00E-83,Q5RAM2,Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3),Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3),GO:0005634; GO:0003708; GO:0043565; GO:0005496; GO:0003707; GO:0008270,nucleus; retinoic acid receptor activity; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,4.00E-11,CHOYP_ER.1.2,,,,,,,ERR3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135491_c0_seq9,615,45.0407,0.64597486,0,0,,5.00E-38,Q91424,Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) (Fragment),Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) (Fragment),GO:0005634; GO:0043565; GO:0003700; GO:0005496; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,ESR1_CNEUN,Aspidoscelis uniparens (Desert grassland whiptail lizard) (Cnemidophorus uniparens),"transcription, DNA-templated [GO:0006351]" comp135492_c0_seq1,1318,42.1851,0.54659446,0,0,,4.00E-36,Q9Y2D8,Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein),Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein),GO:0007155; GO:0031252; GO:0005913; GO:0005634; GO:0043234; GO:0035020; GO:2000145,cell adhesion; cell leading edge; cell-cell adherens junction; nucleus; protein complex; regulation of Rac protein signal transduction; regulation of cell motility,PF11559;,,,,,,,,,ADIP_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; regulation of cell motility [GO:2000145]; regulation of Rac protein signal transduction [GO:0035020] comp135492_c0_seq2,2149,42.0661,0.50515197,123,74,,7.00E-45,Q8CGZ2,Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein),Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein),GO:0030036; GO:0007155; GO:0005913; GO:0030674; GO:0043234,"actin cytoskeleton organization; cell adhesion; cell-cell adherens junction; protein binding, bridging; protein complex",PF11559;,,,,,,,,,ADIP_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; regulation of cell motility [GO:2000145]; regulation of Rac protein signal transduction [GO:0035020] comp135495_c0_seq3,271,35.0554,0.48227607,24,39,,,,,,,,,,,2.00E-21,ruditapes_c18136,,,,,,, comp135502_c0_seq1,1788,43.7919,0.47193219,0,0,,1.00E-19,Q6PGB8,Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (DNA-dependent ATPase SNF2L) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1),Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (DNA-dependent ATPase SNF2L) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1),GO:0005524; GO:0043044; GO:0090537; GO:0003677; GO:0008094; GO:0016589; GO:0036310; GO:0007420; GO:0003682; GO:0006338; GO:0004386; GO:0030182; GO:0000790; GO:0070615; GO:0045893; GO:2000177; GO:0006351,"ATP binding; ATP-dependent chromatin remodeling; CERF complex; DNA binding; DNA-dependent ATPase activity; NURF complex; annealing helicase activity; brain development; chromatin binding; chromatin remodeling; helicase activity; neuron differentiation; nuclear chromatin; nucleosome-dependent ATPase activity; positive regulation of transcription, DNA-dependent; regulation of neural precursor cell proliferation; transcription, DNA-dependent",PF13892;PF09110;PF00271;PF09111;PF00176;,,,,,,,,,SMCA1_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; neuron differentiation [GO:0030182]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135502_c0_seq2,1375,45.8182,0.46368312,0,0,,7.00E-130,Q0P4U8,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1),GO:0005524; GO:0003677; GO:0008094; GO:0036310; GO:0016568; GO:0004386; GO:0005634; GO:0006357,ATP binding; DNA binding; DNA-dependent ATPase activity; annealing helicase activity; chromatin modification; helicase activity; nucleus; regulation of transcription from RNA polymerase II promoter,PF07443;PF00271;PF00176;,,,,,,,,,SMAL1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),angiogenesis [GO:0001525]; cartilage development [GO:0051216]; developmental growth [GO:0048589]; DNA metabolic process [GO:0006259]; embryonic body morphogenesis [GO:0010172]; hemopoiesis [GO:0030097]; mitotic cell cycle [GO:0000278]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp135502_c0_seq3,1234,43.2739,0.3684527,0,0,,2.00E-13,O13682,Helicase swr1 (EC 3.6.4.12),Helicase swr1 (EC 3.6.4.12),GO:0005524; GO:0004003; GO:0003677; GO:0000812; GO:0043486; GO:0006355; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; DNA binding; Swr1 complex; histone exchange; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00271;PF07529;PF00176;,,,,,,,,,SWR1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135502_c0_seq4,1093,44.2818,0.34149585,0,0,,2.00E-11,Q6BKC2,Helicase SWR1 (EC 3.6.4.12),Helicase SWR1 (EC 3.6.4.12),GO:0005524; GO:0003677; GO:0016568; GO:0004386; GO:0005634; GO:0006355; GO:0006351,"ATP binding; DNA binding; chromatin modification; helicase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00271;PF07529;PF00176;,,,,,,,,,SWR1_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),"histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135502_c0_seq5,1516,44.8549,0.47777876,0,0,,1.00E-80,Q9VMX6,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0008094; GO:0036310; GO:0016568; GO:0004386; GO:0005634; GO:0005705; GO:0006357,ATP binding; DNA binding; DNA-dependent ATPase activity; annealing helicase activity; chromatin modification; helicase activity; nucleus; polytene chromosome interband; regulation of transcription from RNA polymerase II promoter,PF07443;PF00271;PF00176;,,,,,,,,,SMAL1_DROME,Drosophila melanogaster (Fruit fly),DNA metabolic process [GO:0006259]; DNA rewinding [GO:0036292]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp135502_c0_seq6,1506,42.2975,0.37580314,0,0,,4.00E-12,Q4WAS9,Helicase swr1 (EC 3.6.4.12),Helicase swr1 (EC 3.6.4.12),GO:0005524; GO:0008026; GO:0003677; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent helicase activity; DNA binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00271;PF07529;PF00176;,3.00E-82,CHOYP_SMARCAL1.1.1,,,,,,,SWR1_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135502_c1_seq2,210,43.3333,0.82343331,4,4,,2.00E-24,B2ZFP3,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1),GO:0005524; GO:0003677; GO:0008094; GO:0001525; GO:0036310; GO:0051216; GO:0016568; GO:0048589; GO:0010172; GO:0004386; GO:0030097; GO:0000278; GO:0005634; GO:0006357,ATP binding; DNA binding; DNA-dependent ATPase activity; angiogenesis; annealing helicase activity; cartilage development; chromatin modification; developmental growth; embryonic body morphogenesis; helicase activity; hemopoiesis; mitotic cell cycle; nucleus; regulation of transcription from RNA polymerase II promoter,PF07443;PF00271;PF00176;,6.00E-36,CHOYP_SMARCAL1.1.1,,,,,,,SMAL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525]; cartilage development [GO:0051216]; developmental growth [GO:0048589]; DNA metabolic process [GO:0006259]; embryonic body morphogenesis [GO:0010172]; hemopoiesis [GO:0030097]; mitotic cell cycle [GO:0000278]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp135506_c1_seq3,541,41.22,0.92914603,30,29,,2.00E-08,O15164,Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),GO:0055074; GO:0071391; GO:0003682; GO:0005829; GO:0034056; GO:0070577; GO:0008285; GO:0045892; GO:0005719; GO:0005634; GO:0005726; GO:0045893; GO:0046777; GO:0030163; GO:0004672; GO:0005102; GO:0042981; GO:0031647; GO:0070562; GO:0043565; GO:0003713; GO:0006366; GO:0004842; GO:0008270,"calcium ion homeostasis; cellular response to estrogen stimulus; chromatin binding; cytosol; estrogen response element binding; histone acetyl-lysine binding; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nuclear euchromatin; nucleus; perichromatin fibrils; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein catabolic process; protein kinase activity; receptor binding; regulation of apoptotic process; regulation of protein stability; regulation of vitamin D receptor signaling pathway; sequence-specific DNA binding; transcription coactivator activity; transcription from RNA polymerase II promoter; ubiquitin-protein ligase activity; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TIF1A_HUMAN,Homo sapiens (Human),"calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]" comp135508_c3_seq1,2015,40.0496,0.44624347,22,4,,1.00E-34,A1L0Y2,Neuralized-like protein 4,Neuralized-like protein 4,GO:0005814,centriole,PF07177;,,,,,,,,,NEUL4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp135512_c0_seq1,1974,45.0355,0.69104987,0,0,,4.00E-109,Q6RY07,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,5.00E-68,CHOYP_ISCW_ISCW016212.2.2,,,,,,,CHIA_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp135512_c0_seq2,1392,44.6839,0.66525506,0,0,,,,,,,,,8.00E-13,CHOYP_DYAK_GE26461.1.1,5.00E-13,ruditapes_c2192,,,,,,, comp135512_c0_seq3,2055,45.3528,0.70298085,0,0,,2.00E-116,Q13231,Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),GO:0008061; GO:0006032; GO:0008843; GO:0005615; GO:0006955; GO:0005764; GO:0000272; GO:0009617,chitin binding; chitin catabolic process; endochitinase activity; extracellular space; immune response; lysosome; polysaccharide catabolic process; response to bacterium,PF01607;PF00704;,3.00E-64,CHOYP_BRAFLDRAFT_281651.4.8,,,,,,,CHIT1_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; response to bacterium [GO:0009617] comp135512_c0_seq4,2270,44.4053,0.67158631,0,0,,2.00E-129,Q13231,Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),GO:0008061; GO:0006032; GO:0008843; GO:0005615; GO:0006955; GO:0005764; GO:0000272; GO:0009617,chitin binding; chitin catabolic process; endochitinase activity; extracellular space; immune response; lysosome; polysaccharide catabolic process; response to bacterium,PF01607;PF00704;,2.00E-81,CHOYP_ISCW_ISCW016212.2.2,,,,,,,CHIT1_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; response to bacterium [GO:0009617] comp135512_c0_seq5,1473,45.146,0.68464512,0,0,,,,,,,,,9.00E-13,CHOYP_DYAK_GE26461.1.1,2.00E-12,ruditapes_c737,,,,,,, comp135512_c0_seq6,1788,45.1342,0.68338838,0,0,,1.00E-29,Q9W303,Chitinase-like protein Idgf4 (Imaginal disk growth factor protein 4),Chitinase-like protein Idgf4 (Imaginal disk growth factor protein 4),GO:0005975; GO:0006032; GO:0004568; GO:0005576; GO:0007444; GO:0008084,carbohydrate metabolic process; chitin catabolic process; chitinase activity; extracellular region; imaginal disc development; imaginal disc growth factor receptor binding,PF00704;,,,,,,,,,IDGF4_DROME,Drosophila melanogaster (Fruit fly),"carbohydrate metabolic process [GO:0005975]; chitin-based cuticle development [GO:0040003]; chitin catabolic process [GO:0006032]; ecdysis, chitin-based cuticle [GO:0018990]; imaginal disc development [GO:0007444]; wound healing [GO:0042060]" comp135512_c0_seq7,1869,45.4789,0.68694917,0,0,,,,,,,,,3.00E-20,CHOYP_BRAFLDRAFT_281651.6.8,5.00E-46,ruditapes_c31443,,,,,,, comp135512_c0_seq8,2189,44.0841,0.66827421,0,0,,1.00E-120,Q6RY07,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,9.00E-78,CHOYP_BRAFLDRAFT_281651.4.8,,,,,,,CHIA_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp135512_c0_seq9,430,48.8372,0.84171923,0,6,,,,,,,,,,,1.00E-20,ruditapes_c4222,,,,,,, comp135513_c5_seq2,1584,40.2778,0.35832954,328,2112,,2.00E-91,Q9ET67,Peroxisome assembly protein 12 (Peroxin-12),Peroxisome assembly protein 12 (Peroxin-12),GO:0005779; GO:0016558; GO:0008270,integral to peroxisomal membrane; protein import into peroxisome matrix; zinc ion binding,PF04757;,6.00E-15,CHOYP_PEX12.1.1,,,,,,,PEX12_CRILO,Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster),peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] comp135514_c0_seq1,1034,39.5551,1.17590507,31,513,,3.00E-27,Q00719,O-methyltransferase MdmC (EC 2.1.1.-),O-methyltransferase MdmC (EC 2.1.1.-),GO:0008171; GO:0017000; GO:0046872,O-methyltransferase activity; antibiotic biosynthetic process; metal ion binding,PF01596;,,,3.00E-21,ruditapes_c16088,,,,,MDMC_STRMY,Streptomyces mycarofaciens,antibiotic biosynthetic process [GO:0017000] comp135515_c1_seq1,1167,35.647,0.5170306,114,731,,,,,,,,,6.00E-14,CHOYP_contig_012619,,,,,,,,, comp135516_c0_seq1,2217,34.8218,0.69507532,14,1995,female>male,6.00E-06,Q8FTH8,Thiamine biosynthesis multifunctional protein ThiED [Includes: Thiamine-phosphate synthase (TMP-PPase) (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase); Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (EC 2.7.1.49) (EC 2.7.4.7) (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)],Thiamine biosynthesis multifunctional protein ThiED [Includes: Thiamine-phosphate synthase (TMP-PPase) (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase); Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (EC 2.7.1.49) (EC 2.7.4.7) (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)],GO:0005524; GO:0008902; GO:0046872; GO:0008972; GO:0009228; GO:0009229; GO:0004789,ATP binding; hydroxymethylpyrimidine kinase activity; metal ion binding; phosphomethylpyrimidine kinase activity; thiamine biosynthetic process; thiamine diphosphate biosynthetic process; thiamine-phosphate diphosphorylase activity,PF08543;PF03070;PF02581;,,,,,,,,,THIED_COREF,Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395),thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229] comp135520_c1_seq1,2125,42.0706,0.7722759,10,0,,2.00E-35,Q8CCG1,Zinc finger C2HC domain-containing protein 1C,Zinc finger C2HC domain-containing protein 1C,GO:0046872,metal ion binding,,,,,,,,,,ZC21C_MOUSE,Mus musculus (Mouse), comp135520_c1_seq2,800,43.25,0.37570415,0,0,,9.00E-42,P97481,Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha),Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha),GO:0003677; GO:0001077; GO:0001525; GO:0001974; GO:0048469; GO:0005737; GO:0001892; GO:0030218; GO:0035035; GO:0030324; GO:0007005; GO:0048625; GO:0042415; GO:0005634; GO:0002027; GO:0043619; GO:0001666; GO:0043565; GO:0004871; GO:0043129; GO:0005667; GO:0007601,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; angiogenesis; blood vessel remodeling; cell maturation; cytoplasm; embryonic placenta development; erythrocyte differentiation; histone acetyltransferase binding; lung development; mitochondrion organization; myoblast fate commitment; norepinephrine metabolic process; nucleus; regulation of heart rate; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; response to hypoxia; sequence-specific DNA binding; signal transducer activity; surfactant homeostasis; transcription factor complex; visual perception,PF11413;PF08778;PF00989;PF08447;,,,,,,,,,EPAS1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell differentiation [GO:0030154]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; hemopoiesis [GO:0030097]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart rate [GO:0002027]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; surfactant homeostasis [GO:0043129]; visual perception [GO:0007601] comp135520_c1_seq3,546,44.1392,0.41697992,0,0,,1.00E-35,P97481,Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha),Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha),GO:0003677; GO:0001077; GO:0001525; GO:0001974; GO:0048469; GO:0005737; GO:0001892; GO:0030218; GO:0035035; GO:0030324; GO:0007005; GO:0048625; GO:0042415; GO:0005634; GO:0002027; GO:0043619; GO:0001666; GO:0043565; GO:0004871; GO:0043129; GO:0005667; GO:0007601,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; angiogenesis; blood vessel remodeling; cell maturation; cytoplasm; embryonic placenta development; erythrocyte differentiation; histone acetyltransferase binding; lung development; mitochondrion organization; myoblast fate commitment; norepinephrine metabolic process; nucleus; regulation of heart rate; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; response to hypoxia; sequence-specific DNA binding; signal transducer activity; surfactant homeostasis; transcription factor complex; visual perception,PF11413;PF08778;PF00989;PF08447;,1.00E-55,CHOYP_LOC100891430.1.1,,,,,,,EPAS1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell differentiation [GO:0030154]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; hemopoiesis [GO:0030097]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart rate [GO:0002027]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; surfactant homeostasis [GO:0043129]; visual perception [GO:0007601] comp135520_c1_seq6,2140,42.1028,0.78701522,3,0,,2.00E-35,Q8CCG1,Zinc finger C2HC domain-containing protein 1C,Zinc finger C2HC domain-containing protein 1C,GO:0046872,metal ion binding,,,,,,,,,,ZC21C_MOUSE,Mus musculus (Mouse), comp135521_c0_seq1,2267,46.5373,0.41791506,0,0,,0,Q6NZC7,SEC23-interacting protein,SEC23-interacting protein,GO:0012507; GO:0005783; GO:0046872,ER to Golgi transport vesicle membrane; endoplasmic reticulum; metal ion binding,PF02862;PF00536;,2.00E-68,CHOYP_SEC23IP.1.1,,,,,,,S23IP_MOUSE,Mus musculus (Mouse),acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286] comp135521_c0_seq10,2227,46.3404,0.41084279,0,0,,0,Q6NZC7,SEC23-interacting protein,SEC23-interacting protein,GO:0012507; GO:0005783; GO:0046872,ER to Golgi transport vesicle membrane; endoplasmic reticulum; metal ion binding,PF02862;PF00536;,,,,,,,,,S23IP_MOUSE,Mus musculus (Mouse),acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286] comp135521_c0_seq11,1837,45.5634,0.48266821,0,0,,1.00E-08,P43125,Protein retinal degeneration B (Probable calcium transporter rdgB),Protein retinal degeneration B (Probable calcium transporter rdgB),GO:0005388; GO:0016059; GO:0005887; GO:0046872; GO:0008525; GO:0046488; GO:0008526; GO:0016056; GO:0007608; GO:0016029; GO:0007601,calcium-transporting ATPase activity; deactivation of rhodopsin mediated signaling; integral to plasma membrane; metal ion binding; phosphatidylcholine transporter activity; phosphatidylinositol metabolic process; phosphatidylinositol transporter activity; rhodopsin mediated signaling pathway; sensory perception of smell; subrhabdomeral cisterna; visual perception,PF02862;PF02121;,,,,,,,,,RDGB_DROME,Drosophila melanogaster (Fruit fly),"cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; phosphatidylinositol metabolic process [GO:0046488]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]" comp135521_c0_seq13,1852,45.5184,0.49091761,5,0,,6.00E-27,O46606,Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),GO:0005737; GO:0016787; GO:0016042; GO:0046872,cytoplasm; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;,,,,,,,,,DDHD1_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042] comp135521_c0_seq15,2276,46.7487,0.41219553,0,0,,,,,,,,,5.00E-81,CHOYP_SEC23IP.1.1,,,,,,,,, comp135521_c0_seq17,1828,45.4048,0.50003581,0,0,,0,Q6NZC7,SEC23-interacting protein,SEC23-interacting protein,GO:0012507; GO:0005783; GO:0046872,ER to Golgi transport vesicle membrane; endoplasmic reticulum; metal ion binding,PF02862;PF00536;,,,,,,,,,S23IP_MOUSE,Mus musculus (Mouse),acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286] comp135521_c0_seq2,1057,46.8307,0.61833114,0,0,,2.00E-27,O46606,Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),GO:0005737; GO:0016787; GO:0016042; GO:0046872,cytoplasm; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;,,,,,,,,,DDHD1_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042] comp135521_c0_seq25,1520,48.2895,0.44337745,0,0,,,,,,,,,6.00E-72,CHOYP_SEC23IP.1.1,,,,,,,,, comp135521_c0_seq3,2291,46.6608,0.41118045,0,0,,2.00E-09,Q7LKZ6,Probable phospholipase C1020.13c (EC 3.1.1.-),Probable phospholipase C1020.13c (EC 3.1.1.-),GO:0044242; GO:0005829; GO:0046872; GO:0005634; GO:0004620,cellular lipid catabolic process; cytosol; metal ion binding; nucleus; phospholipase activity,PF02862;,,,,,,,,,YJMD_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular lipid catabolic process [GO:0044242] comp135521_c0_seq4,2252,46.5364,0.41243802,0,0,,0,Q6NZC7,SEC23-interacting protein,SEC23-interacting protein,GO:0012507; GO:0005783; GO:0046872,ER to Golgi transport vesicle membrane; endoplasmic reticulum; metal ion binding,PF02862;PF00536;,,,,,,,,,S23IP_MOUSE,Mus musculus (Mouse),acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286] comp135521_c0_seq6,1813,45.3944,0.49345342,0,0,,2.00E-26,O46606,Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1),GO:0005737; GO:0016787; GO:0016042; GO:0046872,cytoplasm; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;,,,,,,,,,DDHD1_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042] comp135521_c0_seq7,2251,46.4682,0.40413859,0,0,,2.00E-09,Q7LKZ6,Probable phospholipase C1020.13c (EC 3.1.1.-),Probable phospholipase C1020.13c (EC 3.1.1.-),GO:0044242; GO:0005829; GO:0046872; GO:0005634; GO:0004620,cellular lipid catabolic process; cytosol; metal ion binding; nucleus; phospholipase activity,PF02862;,,,,,,,,,YJMD_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular lipid catabolic process [GO:0044242] comp135521_c0_seq8,1480,48.1757,0.44344832,0,0,,,,,,,,,6.00E-72,CHOYP_SEC23IP.1.1,,,,,,,,, comp135521_c0_seq9,2212,46.4286,0.41196346,0,0,,4.00E-177,O94830,"Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (KIAA0725p) (SAM, WWE and DDHD domain-containing protein 1)","Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (KIAA0725p) (SAM, WWE and DDHD domain-containing protein 1)",GO:0005794; GO:0008219; GO:0005813; GO:0005737; GO:0005829; GO:0005793; GO:0016787; GO:0016042; GO:0046872,Golgi apparatus; cell death; centrosome; cytoplasm; cytosol; endoplasmic reticulum-Golgi intermediate compartment; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;PF00536;PF02825;,,,,,,,,,DDHD2_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of mitochondrial fission [GO:0090141] comp135522_c1_seq3,569,46.2214,0.46148651,0,0,,,,,,,,,3.00E-19,CHOYP_BRAFLDRAFT_128562.2.4,,,,,,,,, comp135522_c1_seq7,294,43.5374,0.72894345,0,0,,3.00E-31,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,8.00E-30,CHOYP_BRAFLDRAFT_128562.2.4,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp135523_c0_seq2,1374,44.1048,0.89908504,4,88,,2.00E-28,P14198,AAC-rich mRNA clone AAC4 protein,AAC-rich mRNA clone AAC4 protein,GO:0016021,integral to membrane,,2.00E-53,CHOYP_CAOG_08159.1.2,1.00E-96,ruditapes_c9410,,,,,AAC4_DICDI,Dictyostelium discoideum (Slime mold), comp135524_c0_seq4,960,36.0417,0.44966626,7,35,,7.00E-23,Q9LDH0,"Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)","Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)",GO:0032580; GO:0005797; GO:0000139; GO:0050513; GO:0016021; GO:0031204; GO:0006487,"Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; glycoprotein 2-beta-D-xylosyltransferase activity; integral to membrane; posttranslational protein targeting to membrane, translocation; protein N-linked glycosylation",PF04577;,,,,,,,,,XYLT_ARATH,Arabidopsis thaliana (Mouse-ear cress),"posttranslational protein targeting to membrane, translocation [GO:0031204]; protein N-linked glycosylation [GO:0006487]" comp135524_c0_seq7,998,35.9719,0.43483441,0,6,,6.00E-23,Q9LDH0,"Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)","Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)",GO:0032580; GO:0005797; GO:0000139; GO:0050513; GO:0016021; GO:0031204; GO:0006487,"Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; glycoprotein 2-beta-D-xylosyltransferase activity; integral to membrane; posttranslational protein targeting to membrane, translocation; protein N-linked glycosylation",PF04577;,,,,,,,,,XYLT_ARATH,Arabidopsis thaliana (Mouse-ear cress),"posttranslational protein targeting to membrane, translocation [GO:0031204]; protein N-linked glycosylation [GO:0006487]" comp135525_c0_seq3,2299,38.495,0.45832599,14,99,,7.00E-20,Q3UHX0,Nucleolar protein 8,Nucleolar protein 8,GO:0006260; GO:0003723; GO:0005730; GO:0000166; GO:0030307; GO:0006364,DNA replication; RNA binding; nucleolus; nucleotide binding; positive regulation of cell growth; rRNA processing,PF00076;,,,,,,,,,NOL8_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; positive regulation of cell growth [GO:0030307]; rRNA processing [GO:0006364] comp135526_c1_seq1,1729,36.9578,0.84080568,45,172,,1.00E-27,P40239,CD9 antigen (CD antigen CD9),CD9 antigen (CD antigen CD9),GO:0007155; GO:0006928; GO:0009897; GO:0007342; GO:0016021; GO:0008285; GO:0030913,cell adhesion; cellular component movement; external side of plasma membrane; fusion of sperm to egg plasma membrane; integral to membrane; negative regulation of cell proliferation; paranodal junction assembly,PF00335;,3.00E-38,CHOYP_CD81.1.1,,,,,,,CD9_FELCA,Felis catus (Cat) (Felis silvestris catus),cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; fusion of sperm to egg plasma membrane [GO:0007342]; movement of cell or subcellular component [GO:0006928]; paranodal junction assembly [GO:0030913]; receptor internalization [GO:0031623] comp135526_c1_seq2,282,41.1348,0.75804525,0,0,,3.00E-11,P40239,CD9 antigen (CD antigen CD9),CD9 antigen (CD antigen CD9),GO:0007155; GO:0006928; GO:0009897; GO:0007342; GO:0016021; GO:0008285; GO:0030913,cell adhesion; cellular component movement; external side of plasma membrane; fusion of sperm to egg plasma membrane; integral to membrane; negative regulation of cell proliferation; paranodal junction assembly,PF00335;,,,,,,,,,CD9_FELCA,Felis catus (Cat) (Felis silvestris catus),cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; fusion of sperm to egg plasma membrane [GO:0007342]; movement of cell or subcellular component [GO:0006928]; paranodal junction assembly [GO:0030913]; receptor internalization [GO:0031623] comp135527_c0_seq1,2861,42.9221,0.43717847,0,11,,2.00E-109,Q8C0W1,Ankyrin repeat and MYND domain-containing protein 1,Ankyrin repeat and MYND domain-containing protein 1,GO:0046872,metal ion binding,PF12796;PF02493;PF01753;,,,,,,,,,ANMY1_MOUSE,Mus musculus (Mouse), comp135527_c0_seq3,2845,42.9877,0.43826022,9,0,,9.00E-98,Q9P2S6,Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13),Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13),GO:0046872,metal ion binding,PF12796;PF02493;PF01753;,,,,,,,,,ANKY1_HUMAN,Homo sapiens (Human), comp135527_c0_seq6,2588,43.0448,0.42918862,3,0,,8.00E-07,Q5EA33,Ankyrin repeat domain-containing protein 49,Ankyrin repeat domain-containing protein 49,GO:0045893,"positive regulation of transcription, DNA-dependent",,4.00E-108,CHOYP_LOC578371.1.1,,,,,,,ANR49_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]" comp135527_c1_seq1,775,41.8065,0.43546649,70,10,,2.00E-34,Q9P2S6,Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13),Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13),GO:0046872,metal ion binding,PF12796;PF02493;PF01753;,,,,,,,,,ANKY1_HUMAN,Homo sapiens (Human), comp135530_c0_seq1,2949,37.5042,0.35127415,3200,96,,7.00E-91,Q32NR4,Tetratricopeptide repeat protein 29 (TPR repeat protein 29),Tetratricopeptide repeat protein 29 (TPR repeat protein 29),,,,1.00E-90,CHOYP_BRAFLDRAFT_121105.1.1,,,,,,,TTC29_XENLA,Xenopus laevis (African clawed frog), comp135531_c0_seq1,945,42.328,0.52855932,0,5,,2.00E-08,P50214,Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase),Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase),GO:0051287; GO:0006097; GO:0004450; GO:0000287; GO:0006099,NAD binding; glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; magnesium ion binding; tricarboxylic acid cycle,PF00180;,,,,,,,,,IDH_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576),glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] comp135531_c0_seq2,1394,41.3917,0.42205221,3,20,,1.00E-38,Q58991,Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87) (Isohomocitrate dehydrogenase) (IHDH) (NAD-dependent threo-isohomocitrate dehydrogenase),Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87) (Isohomocitrate dehydrogenase) (IHDH) (NAD-dependent threo-isohomocitrate dehydrogenase),GO:0003862; GO:0051287; GO:0019298; GO:0047046; GO:0009098; GO:0000287,3-isopropylmalate dehydrogenase activity; NAD binding; coenzyme B biosynthetic process; homoisocitrate dehydrogenase activity; leucine biosynthetic process; magnesium ion binding,PF00180;,1.00E-111,CHOYP_LOC100371176.1.1,,,,,,,AKSF_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),coenzyme B biosynthetic process [GO:0019298]; leucine biosynthetic process [GO:0009098] comp135531_c0_seq3,1410,41.4894,0.41521514,14,6,,1.00E-27,Q9FMT1,"3-isopropylmalate dehydrogenase 3, chloroplastic (3-IPM-DH 3) (IMDH 3) (EC 1.1.1.85) (Beta-IPM dehydrogenase 3)","3-isopropylmalate dehydrogenase 3, chloroplastic (3-IPM-DH 3) (IMDH 3) (EC 1.1.1.85) (Beta-IPM dehydrogenase 3)",GO:0003862; GO:0051287; GO:0009570; GO:0019761; GO:0009098; GO:0000287; GO:0009651,3-isopropylmalate dehydrogenase activity; NAD binding; chloroplast stroma; glucosinolate biosynthetic process; leucine biosynthetic process; magnesium ion binding; response to salt stress,PF00180;,,,,,,,,,LEU33_ARATH,Arabidopsis thaliana (Mouse-ear cress),glucosinolate biosynthetic process [GO:0019761]; leucine biosynthetic process [GO:0009098]; response to salt stress [GO:0009651] comp135531_c0_seq4,1443,41.2335,0.44304567,14,0,,1.00E-137,P41565,"Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma)","Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma)",GO:0006103; GO:0005524; GO:0051287; GO:0006734; GO:0004449; GO:0006102; GO:0000287; GO:0005962; GO:0045926; GO:0006099,2-oxoglutarate metabolic process; ATP binding; NAD binding; NADH metabolic process; isocitrate dehydrogenase (NAD+) activity; isocitrate metabolic process; magnesium ion binding; mitochondrial isocitrate dehydrogenase complex (NAD+); negative regulation of growth; tricarboxylic acid cycle,PF00180;,1.00E-111,CHOYP_LOC100371176.1.1,,,,,,,IDHG1_RAT,Rattus norvegicus (Rat),2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; negative regulation of growth [GO:0045926]; tricarboxylic acid cycle [GO:0006099] comp135531_c0_seq5,1459,41.3982,0.45084113,0,0,,1.00E-133,P41564,"Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) (Fragment)","Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) (Fragment)",GO:0005524; GO:0051287; GO:0004449; GO:0006102; GO:0000287; GO:0005739; GO:0006099,ATP binding; NAD binding; isocitrate dehydrogenase (NAD+) activity; isocitrate metabolic process; magnesium ion binding; mitochondrion; tricarboxylic acid cycle,PF00180;,2.00E-34,CHOYP_BRAFLDRAFT_124233.1.1,,,,,,,IDH3G_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099] comp135536_c1_seq1,1526,35.7143,0.41721329,28,17,,,,,,,,,2.00E-47,CHOYP_CK070.1.1,,,,,,,,, comp135536_c1_seq5,1540,35.5844,0.41655984,28,3,,1.00E-90,Q5I0R4,Uncharacterized protein C11orf70 homolog,Uncharacterized protein C11orf70 homolog,,,PF14926;,2.00E-47,CHOYP_CK070.1.1,,,,,,,CK070_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp135540_c0_seq1,1054,41.9355,0.56255178,0,9,,,,,,,,,1.00E-33,CHOYP_LOC100367637.1.1,,,,,,,,, comp135540_c0_seq2,1135,41.9383,0.54157365,6,105,,3.00E-104,Q96C86,m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS),m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS),GO:0000340; GO:0036245; GO:0005829; GO:0000290; GO:0043928; GO:0050072; GO:0045292; GO:0005739; GO:0043069; GO:0005634,"RNA 7-methylguanosine cap binding; cellular response to menadione; cytosol; deadenylation-dependent decapping of nuclear-transcribed mRNA; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; m7G(5')pppN diphosphatase activity; mRNA cis splicing, via spliceosome; mitochondrion; negative regulation of programmed cell death; nucleus",PF05652;,2.00E-13,CHOYP_DCPS.1.1,,,,,,,DCPS_HUMAN,Homo sapiens (Human),"cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]" comp135541_c0_seq1,1107,46.1608,0.54541024,15,13,,1.00E-30,Q03319,Probable ATP-dependent RNA helicase prh1 (EC 3.6.4.13),Probable ATP-dependent RNA helicase prh1 (EC 3.6.4.13),GO:0005524; GO:0004004; GO:0003723; GO:0006397; GO:0005730; GO:0042254,ATP binding; ATP-dependent RNA helicase activity; RNA binding; mRNA processing; nucleolus; ribosome biogenesis,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,PRH1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mRNA processing [GO:0006397]; ribosome biogenesis [GO:0042254]; RNA processing [GO:0006396] comp135541_c0_seq2,1879,46.4609,0.53424283,49,51,,0,Q68FK8,ATP-dependent RNA helicase A-like protein (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),ATP-dependent RNA helicase A-like protein (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),GO:0005524; GO:0008026; GO:0070937; GO:0003677; GO:0003723; GO:0005634,ATP binding; ATP-dependent helicase activity; CRD-mediated mRNA stability complex; DNA binding; RNA binding; nucleus,PF00270;PF00035;PF04408;PF00271;PF07717;,0,CHOYP_BRAFLDRAFT_124637.1.1,,,,,,,DHX9_XENLA,Xenopus laevis (African clawed frog), comp135541_c0_seq3,1280,49.4531,0.5000904,0,0,,8.00E-34,Q5R746,YTH domain-containing protein 2,YTH domain-containing protein 2,GO:0004386,helicase activity,PF04408;PF07717;PF04146;,9.00E-139,CHOYP_BRAFLDRAFT_124637.1.1,,,,,,,YTDC2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp135541_c0_seq5,939,46.7519,0.52798063,0,0,,4.00E-96,Q28141,ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),GO:0005524; GO:0008026; GO:0070937; GO:0003677; GO:0003723; GO:0005730; GO:0030529,ATP binding; ATP-dependent helicase activity; CRD-mediated mRNA stability complex; DNA binding; RNA binding; nucleolus; ribonucleoprotein complex,PF00270;PF00035;PF04408;PF00271;PF07717;,,,,,,,,,DHX9_BOVIN,Bos taurus (Bovine),rhythmic process [GO:0048511]; RNA processing [GO:0006396] comp135541_c1_seq1,219,55.2511,0.18313367,3,0,,,,,,,,,8.00E-16,CHOYP_ISCW_ISCW009103.1.1,,,,,,,,, comp135546_c0_seq1,1069,44.7147,0.55970467,0,0,,6.00E-133,Q9P2G1,Ankyrin repeat and IBR domain-containing protein 1,Ankyrin repeat and IBR domain-containing protein 1,GO:0008270,zinc ion binding,PF00023;PF01485;,,,,,,,,,AKIB1_HUMAN,Homo sapiens (Human),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp135546_c0_seq3,658,45.5927,0.50786644,0,0,,,,,,,,,3.00E-72,CHOYP_LOC100368072.1.1,,,,,,,,, comp135546_c0_seq4,1009,44.4995,0.55193545,0,0,,1.00E-109,Q9P2G1,Ankyrin repeat and IBR domain-containing protein 1,Ankyrin repeat and IBR domain-containing protein 1,GO:0008270,zinc ion binding,PF00023;PF01485;,5.00E-115,CHOYP_LOC100368072.1.1,,,,,,,AKIB1_HUMAN,Homo sapiens (Human),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp135546_c0_seq7,718,45.8217,0.52281005,0,0,,2.00E-16,Q54CX4,Uncharacterized protein DDB_G0292642,Uncharacterized protein DDB_G0292642,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF01485;PF13639;,,,,,,,,,Y5521_DICDI,Dictyostelium discoideum (Slime mold),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp135549_c2_seq1,323,45.2012,0.49231241,1,67,,1.00E-13,Q26474,Lachesin,Lachesin,GO:0031225; GO:0007155; GO:0005886,anchored to membrane; cell adhesion; plasma membrane,PF07679;,,,,,,,,,LACH_SCHAM,Schistocerca americana (American grasshopper),cell adhesion [GO:0007155]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp135551_c0_seq1,2326,43.5942,0.54691825,112,231,,1.00E-75,P49816,Tuberin (Tuberous sclerosis 2 protein homolog),Tuberin (Tuberous sclerosis 2 protein homolog),GO:0005794; GO:0005097; GO:0033596; GO:0006953; GO:0005901; GO:0030030; GO:0030425; GO:0045184; GO:0030426; GO:0048009; GO:0043407; GO:0032007; GO:0030178; GO:0045792; GO:0050680; GO:0043025; GO:0005634; GO:0048471; GO:0019902; GO:0051291; GO:0051260; GO:0043491; GO:0051726; GO:0046626,Golgi apparatus; Rab GTPase activator activity; TSC1-TSC2 complex; acute-phase response; caveola; cell projection organization; dendrite; establishment of protein localization; growth cone; insulin-like growth factor receptor signaling pathway; negative regulation of MAP kinase activity; negative regulation of TOR signaling cascade; negative regulation of Wnt receptor signaling pathway; negative regulation of cell size; negative regulation of epithelial cell proliferation; neuronal cell body; nucleus; perinuclear region of cytoplasm; phosphatase binding; protein heterooligomerization; protein homooligomerization; protein kinase B signaling cascade; regulation of cell cycle; regulation of insulin receptor signaling pathway,PF11864;PF02145;PF03542;,1.00E-64,CHOYP_LOC101078033.1.1,,,,,,,TSC2_RAT,Rattus norvegicus (Rat),cell projection organization [GO:0030030]; establishment of protein localization [GO:0045184]; negative regulation of cell size [GO:0045792]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of cell cycle [GO:0051726]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp135552_c2_seq1,542,45.3875,0.7259383,8,17,,1.00E-64,C3YDS7,NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase),NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase),GO:0016853; GO:0046872; GO:0000166,isomerase activity; metal ion binding; nucleotide binding,PF03853;,4.00E-56,CHOYP_OTU5B.1.1,3.00E-30,ruditapes_c29902,,,,,NNRE_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus), comp135552_c2_seq2,1101,44.0509,0.90597136,11,20,,3.00E-108,C3YDS7,NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase),NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase),GO:0016853; GO:0046872; GO:0000166,isomerase activity; metal ion binding; nucleotide binding,PF03853;,2.00E-33,CHOYP_NNRE.2.2,,,,,,,NNRE_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus), comp135555_c0_seq1,1996,45.0401,1.15702218,2411,3,male>female,0,Q6JEL2,Kelch-like protein 10,Kelch-like protein 10,GO:0000902; GO:0005737; GO:0009566; GO:0048873; GO:0048808; GO:0008584; GO:0016567; GO:0007286,cell morphogenesis; cytoplasm; fertilization; homeostasis of number of cells within a tissue; male genitalia morphogenesis; male gonad development; protein ubiquitination; spermatid development,PF07707;PF00651;PF01344;,0,CHOYP_KLHL10.2.2,,,,,,,KLH10_HUMAN,Homo sapiens (Human),cell morphogenesis [GO:0000902]; fertilization [GO:0009566]; homeostasis of number of cells within a tissue [GO:0048873]; male genitalia morphogenesis [GO:0048808]; male gonad development [GO:0008584]; protein ubiquitination [GO:0016567]; spermatid development [GO:0007286] comp135557_c0_seq1,487,45.3799,0.73029906,12,44,,,,,,,,,4.00E-17,CHOYP_contig_015253,,,,,,,,, comp135557_c1_seq1,1610,43.7267,0.54661808,19,18,,3.00E-103,Q0JRZ9,FCH domain only protein 2,F-BAR domain only protein 2,GO:0048268; GO:0030136; GO:0072583; GO:0005905; GO:0010324; GO:0005546; GO:0001786; GO:0005886; GO:0072659,"clathrin coat assembly; clathrin-coated vesicle; clathrin-mediated endocytosis; coated pit; membrane invagination; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; plasma membrane; protein localization to plasma membrane",PF00611;PF10291;,2.00E-65,CHOYP_LOC100123907.1.1,,,,,,,FCHO2_HUMAN,Homo sapiens (Human),clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659] comp135557_c1_seq2,1331,46.0556,0.56749707,3,14,,,,,,,,,2.00E-59,CHOYP_LOC100123907.1.1,,,,,,,,, comp135560_c2_seq1,1549,45.6423,0.41819983,0,0,,2.00E-39,Q9UBG0,C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280),C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280),GO:0030246; GO:0006897; GO:0016021,carbohydrate binding; endocytosis; integral to membrane,PF00040;PF00059;,,,,,,,,,MRC2_HUMAN,Homo sapiens (Human),collagen catabolic process [GO:0030574]; endocytosis [GO:0006897]; osteoblast differentiation [GO:0001649] comp135560_c2_seq10,409,43.7653,0.36795092,4,0,,2.00E-15,A3FM55,C-type lectin 1 (CTL),C-type lectin 1 (CTL),GO:0030246; GO:0005576; GO:0046872,carbohydrate binding; extracellular region; metal ion binding,PF00059;,,,,,,,,,LEC1_LAPHA,Hydrophis hardwickii (Hardwick's spine-bellied seasnake) (Lapemis hardwickii), comp135560_c2_seq11,775,47.0968,0.42474072,0,0,,8.00E-28,Q4TU93,C-type mannose receptor 2 (Endocytic receptor 180) (Macrophage mannose receptor 2) (CD antigen CD280),C-type mannose receptor 2 (Endocytic receptor 180) (Macrophage mannose receptor 2) (CD antigen CD280),GO:0030246; GO:0006897; GO:0016021; GO:0005886,carbohydrate binding; endocytosis; integral to membrane; plasma membrane,PF00040;PF00059;,,,,,,,,,MRC2_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897] comp135560_c2_seq12,876,44.5205,0.42100546,3,0,,3.00E-07,Q3LUH2,C-type lectin domain family 6 member A (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2),C-type lectin domain family 6 member A (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2),GO:0030246; GO:0050832; GO:0045087; GO:0016021; GO:0043123; GO:0050715,carbohydrate binding; defense response to fungus; innate immune response; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cytokine secretion,PF00059;,,,,,,,,,CLC6A_BOVIN,Bos taurus (Bovine),adaptive immune response [GO:0002250]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp135560_c2_seq14,651,40.3994,0.46061571,0,0,,1.00E-15,Q6ZS10,"C-type lectin domain family 17, member A (Prolectin)","C-type lectin domain family 17, member A (Prolectin)",GO:0009986; GO:0042806; GO:0016021; GO:0005537; GO:0046872,cell surface; fucose binding; integral to membrane; mannose binding; metal ion binding,PF00059;,,,,,,,,,CL17A_HUMAN,Homo sapiens (Human), comp135560_c2_seq15,1008,42.4603,0.38609442,0,0,,8.00E-36,Q61830,Macrophage mannose receptor 1 (MMR) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (CD antigen CD206),GO:0009986; GO:0010008; GO:0016021; GO:0005537; GO:0005886; GO:0006898; GO:0004888,cell surface; endosome membrane; integral to membrane; mannose binding; plasma membrane; receptor-mediated endocytosis; transmembrane signaling receptor activity,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp135560_c2_seq16,410,42.9268,0.38263295,1,0,,2.00E-18,P20693,Low affinity immunoglobulin epsilon Fc receptor (Fc-epsilon-RII) (Lymphocyte IgE receptor) (CD antigen CD23),Low affinity immunoglobulin epsilon Fc receptor (Fc-epsilon-RII) (Lymphocyte IgE receptor) (CD antigen CD23),GO:0030246; GO:0009897; GO:0016021; GO:0046872; GO:0002925; GO:0051712; GO:0051000; GO:0051770,carbohydrate binding; external side of plasma membrane; integral to membrane; metal ion binding; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of killing of cells of other organism; positive regulation of nitric-oxide synthase activity; positive regulation of nitric-oxide synthase biosynthetic process,PF00059;,,,,,,,,,FCER2_MOUSE,Mus musculus (Mouse),positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770] comp135560_c2_seq2,425,48.9412,0.27778449,0,0,,4.00E-10,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp135560_c2_seq3,1020,45.2941,0.44982325,0,0,,2.00E-17,Q90953,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp135560_c2_seq6,1257,46.5394,0.44733689,0,0,,8.00E-33,P49259,Secretory phospholipase A2 receptor (PLA2-R) (PLA2R) (180 kDa secretory phospholipase A2 receptor) (M-type receptor) [Cleaved into: Soluble secretory phospholipase A2 receptor (Soluble PLA2-R) (Soluble PLA2R)],Secretory phospholipase A2 receptor (PLA2-R) (PLA2R) (180 kDa secretory phospholipase A2 receptor) (M-type receptor) [Cleaved into: Soluble secretory phospholipase A2 receptor (Soluble PLA2-R) (Soluble PLA2R)],GO:0030246; GO:0009986; GO:0001816; GO:0005576; GO:0016021; GO:1900139; GO:1900138; GO:0090403; GO:0043274; GO:0005886; GO:0043517; GO:0090238; GO:0072593; GO:0004872; GO:0006898; GO:0090399,"carbohydrate binding; cell surface; cytokine production; extracellular region; integral to membrane; negative regulation of arachidonic acid secretion; negative regulation of phospholipase A2 activity; oxidative stress-induced premature senescence; phospholipase binding; plasma membrane; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of arachidonic acid secretion; reactive oxygen species metabolic process; receptor activity; receptor-mediated endocytosis; replicative senescence",PF00040;PF00059;,,,,,,,,,PLA2R_BOVIN,Bos taurus (Bovine),"cytokine production [GO:0001816]; negative regulation of arachidonic acid secretion [GO:1900139]; negative regulation of phospholipase A2 activity [GO:1900138]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; replicative senescence [GO:0090399]" comp135560_c2_seq8,1614,46.4684,0.41046716,0,0,,4.00E-65,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp135561_c0_seq1,1272,33.6478,0.52954603,97,425,,8.00E-07,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp135565_c0_seq3,1209,41.5219,0.98027135,0,0,,3.00E-36,Q27312,ADP-ribosyl cyclase (ADRC) (EC 3.2.2.5) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase),ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase) (ADPRC) (ADRC) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase),GO:0003953; GO:0016023; GO:0007338,NAD+ nucleosidase activity; cytoplasmic membrane-bounded vesicle; single fertilization,PF02267;,,,,,,,,,NADA_APLKU,Aplysia kurodai (Kuroda's sea hare),single fertilization [GO:0007338] comp135567_c0_seq1,1712,34.8131,0.50298161,42,134,,4.00E-07,P36416,N-terminal acetyltransferase complex ARD1 subunit homolog (EC 2.3.1.-),N-terminal acetyltransferase complex ARD1 subunit homolog (EC 2.3.1.-),GO:0008080,N-acetyltransferase activity,PF00583;,9.00E-96,CHOYP_NAA30.1.1,,,,,,,ARD1_DICDI,Dictyostelium discoideum (Slime mold),internal protein amino acid acetylation [GO:0006475]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-serine acetylation [GO:0017198] comp135567_c0_seq2,1803,34.7199,0.47959115,110,304,,4.00E-79,Q0IHH1,N-alpha-acetyltransferase 30 (EC 2.3.1.-) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit),N-alpha-acetyltransferase 30 (EC 2.3.1.88) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit),GO:0008080,N-acetyltransferase activity,PF00583;,,,,,,,,,NAA30_XENLA,Xenopus laevis (African clawed frog), comp135570_c0_seq1,956,44.9791,0.52123104,100,77,,6.00E-42,Q92616,Translational activator GCN1 (HsGCN1) (GCN1-like protein 1),eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1),GO:0006417; GO:0005840; GO:0008135,"regulation of translation; ribosome; translation factor activity, nucleic acid binding",,,,,,,,,,GCN1L_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of translation [GO:0006417] comp135581_c0_seq1,1180,42.1186,0.5752001,292,1306,,,,,,,,,,,7.00E-36,ruditapes_c12763,,,,,,, comp135582_c0_seq1,276,40.5797,0.53613607,7,8,,1.00E-06,Q9BRR9,Rho GTPase-activating protein 9 (Rho-type GTPase-activating protein 9),Rho GTPase-activating protein 9 (Rho-type GTPase-activating protein 9),GO:0005096; GO:0005829; GO:0005543; GO:0051056; GO:0007264,GTPase activator activity; cytosol; phospholipid binding; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00169;PF00620;PF00018;,,,,,,,,,RHG09_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp135582_c4_seq1,269,38.29,0.20362272,3,9,,3.00E-22,Q9Z1N3,Unconventional myosin-IXa (Myr 7) (Unconventional myosin-9a),Unconventional myosin-IXa (Myr 7) (Unconventional myosin-9a),GO:0005524; GO:0005096; GO:0005737; GO:0016021; GO:0035556; GO:0046872; GO:0003774; GO:0016459; GO:0043547,ATP binding; GTPase activator activity; cytoplasm; integral to membrane; intracellular signal transduction; metal ion binding; motor activity; myosin complex; positive regulation of GTPase activity,PF00612;PF00063;PF00788;PF00620;,8.00E-17,CHOYP_LOC100870108.3.4,,,,,,,MYO9A_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556] comp135582_c5_seq1,296,38.1757,0.65750276,7,9,,2.00E-09,P16054,Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon),Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon),GO:0005524; GO:0035669; GO:0003785; GO:0004699; GO:0007155; GO:0007049; GO:0051301; GO:0071944; GO:0071361; GO:0071456; GO:0007635; GO:0005856; GO:0005829; GO:0005783; GO:0008047; GO:0035276; GO:0035556; GO:0031663; GO:0035641; GO:0002281; GO:0016020; GO:0046872; GO:0005739; GO:0005634; GO:0048471; GO:0005886; GO:0043123; GO:0043410; GO:0030838; GO:0043085; GO:0010811; GO:2001031; GO:0032467; GO:0010634; GO:0010763; GO:0032024; GO:0050996; GO:0070257; GO:0032230; GO:0090303; GO:0030546; GO:0061178; GO:0050730; GO:0051209; GO:0043278,"ATP binding; TRAM-dependent toll-like receptor 4 signaling pathway; actin monomer binding; calcium-independent protein kinase C activity; cell adhesion; cell cycle; cell division; cell periphery; cellular response to ethanol; cellular response to hypoxia; chemosensory behavior; cytoskeleton; cytosol; endoplasmic reticulum; enzyme activator activity; ethanol binding; intracellular signal transduction; lipopolysaccharide-mediated signaling pathway; locomotory exploration behavior; macrophage activation involved in immune response; membrane; metal ion binding; mitochondrion; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAPK cascade; positive regulation of actin filament polymerization; positive regulation of catalytic activity; positive regulation of cell-substrate adhesion; positive regulation of cellular glucuronidation; positive regulation of cytokinesis; positive regulation of epithelial cell migration; positive regulation of fibroblast migration; positive regulation of insulin secretion; positive regulation of lipid catabolic process; positive regulation of mucus secretion; positive regulation of synaptic transmission, GABAergic; positive regulation of wound healing; receptor activator activity; regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of peptidyl-tyrosine phosphorylation; release of sequestered calcium ion into cytosol; response to morphine",PF00130;PF00168;PF00069;PF00433;,,,,,,,,,KPCE_MOUSE,Mus musculus (Mouse),"cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to prostaglandin E stimulus [GO:0071380]; chemosensory behavior [GO:0007635]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; locomotory exploration behavior [GO:0035641]; macrophage activation involved in immune response [GO:0002281]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cellular glucuronidation [GO:2001031]; positive regulation of cytokinesis [GO:0032467]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion [GO:0032024]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; release of sequestered calcium ion into cytosol [GO:0051209]; response to morphine [GO:0043278]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669]" comp135589_c0_seq2,1282,36.0374,0.639827,168,832,,3.00E-13,A5PJW2,Transmembrane protein 223,Transmembrane protein 223,GO:0016021,integral to membrane,,,,,,,,,,TM223_BOVIN,Bos taurus (Bovine),nervous system development [GO:0007399] comp135590_c1_seq1,1482,42.7126,0.50472495,103,127,,,,,,,,,,,7.00E-18,ruditapes_c1573,,,,,,, comp135593_c0_seq1,1112,27.0683,0.24630453,405,1636,,,,,,,,,,,3.00E-14,ruditapes_lrc17640,,,,,,, comp135595_c3_seq1,2815,44.8668,0.64738617,24,14,,1.00E-121,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,6.00E-12,CHOYP_CADN.3.3,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp135595_c3_seq2,315,40.6349,1.24533275,0,0,,,,,,,,,1.00E-21,CHOYP_CADN.2.3,,,,,,,,, comp135595_c3_seq3,2483,43.6569,0.56868141,4,10,,8.00E-12,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp135595_c7_seq1,404,40.3465,0.73392174,13,0,,4.00E-09,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,,,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp135597_c0_seq1,619,43.4572,0.24619987,10,11,,5.00E-09,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp135597_c0_seq3,622,43.7299,0.14115018,5,0,,3.00E-08,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp135598_c0_seq3,1055,38.1043,0.42158882,0,21,,2.00E-74,Q5R605,Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a),Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a),GO:0000794; GO:0000910; GO:0005769; GO:0012505; GO:0010008; GO:0016458; GO:0005815; GO:0007076; GO:0045014; GO:0016363; GO:0015031; GO:0006351; GO:0016192,"condensed nuclear chromosome; cytokinesis; early endosome; endomembrane system; endosome membrane; gene silencing; microtubule organizing center; mitotic chromosome condensation; negative regulation of transcription by glucose; nuclear matrix; protein transport; transcription, DNA-dependent; vesicle-mediated transport",PF03357;,7.00E-82,CHOYP_BRAFLDRAFT_278938.1.1,,,,,,,CHM1A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell separation after cytokinesis [GO:0000920]; gene silencing [GO:0016458]; mitotic chromosome condensation [GO:0007076]; mitotic metaphase plate congression [GO:0007080]; negative regulation of transcription by glucose [GO:0045014]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; transcription, DNA-templated [GO:0006351]; vacuolar transport [GO:0007034]; vesicle-mediated transport [GO:0016192]" comp135607_c0_seq1,1346,37.0728,0.45594803,67,355,,3.00E-139,Q5E9U9,Nitrogen permease regulator 2-like protein (NPR2-like protein) (Tumor suppressor candidate 4),Nitrogen permease regulator 2-like protein (NPR2-like protein) (Tumor suppressor candidate 4),GO:0005096; GO:0005737; GO:0033673; GO:0043547; GO:0004672,GTPase activator activity; cytoplasm; negative regulation of kinase activity; positive regulation of GTPase activity; protein kinase activity,PF06218;,1.00E-22,CHOYP_LOC100377135.1.1,,,,,,,NPRL2_BOVIN,Bos taurus (Bovine),cellular response to amino acid starvation [GO:0034198]; negative regulation of kinase activity [GO:0033673]; negative regulation of TOR signaling [GO:0032007] comp135609_c0_seq3,802,42.2693,0.50436257,1,0,,,,,,,,,3.00E-28,CHOYP_LOC576762.1.1,,,,,,,,, comp135611_c1_seq1,667,40.03,0.61018635,194,709,,8.00E-37,Q95KE5,"39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Retina-specific 15.7 kDa protein)","39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Retina-specific 15.7 kDa protein)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF05047;,,,8.00E-64,ruditapes_c14976,,,,,RM43_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp135617_c0_seq1,2075,35.6145,0.61047788,182,731,,0,Q5R6K8,Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16),Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16),GO:0005737; GO:0046872; GO:0005815; GO:0005634; GO:0004722; GO:0010569,cytoplasm; metal ion binding; microtubule organizing center; nucleus; protein serine/threonine phosphatase activity; regulation of double-strand break repair via homologous recombination,PF00149;,0,CHOYP_PP4C.1.1,8.00E-32,ruditapes_c13481,,,,,PP4C_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),regulation of double-strand break repair via homologous recombination [GO:0010569] comp135621_c0_seq1,994,30.3823,0.26650623,104,647,,,,,,,,,,,1.00E-13,ruditapes_c9496,,,,,,, comp135624_c0_seq1,598,36.2876,0.50892241,0,2,,2.00E-17,Q966L8,Transcription factor che-1 (Abnormal chemotaxis protein 1),Transcription factor che-1 (Abnormal chemotaxis protein 1),GO:0006935; GO:0046872; GO:0030182; GO:0005634; GO:0045944; GO:0050920; GO:0043565; GO:0006351,"chemotaxis; metal ion binding; neuron differentiation; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of chemotaxis; sequence-specific DNA binding; transcription, DNA-dependent",PF00096;,,,,,,,,,CHE1_CAEEL,Caenorhabditis elegans,"chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; neuron differentiation [GO:0030182]; positive regulation of chemotaxis [GO:0050921]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of chemotaxis [GO:0050920]; response to alkaline pH [GO:0010446]; response to inorganic substance [GO:0010035]; response to lithium ion [GO:0010226]; response to magnesium ion [GO:0032026]; response to methionine [GO:1904640]; response to salt [GO:1902074]; transcription, DNA-templated [GO:0006351]" comp135624_c0_seq11,884,33.5973,0.6929995,0,100,,7.00E-19,Q00911,Early growth response protein 4 (EGR-4) (Early response protein NGFI-C) (Nerve growth factor-induced protein C) (NGFI-C),Early growth response protein 4 (EGR-4) (Early response protein NGFI-C) (Nerve growth factor-induced protein C) (NGFI-C),GO:0000977; GO:0071320; GO:0071371; GO:0071363; GO:0005737; GO:0046872; GO:0043066; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"RNA polymerase II regulatory region sequence-specific DNA binding; cellular response to cAMP; cellular response to gonadotropin stimulus; cellular response to growth factor stimulus; cytoplasm; metal ion binding; negative regulation of apoptotic process; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,,,,,,,,,EGR4_RAT,Rattus norvegicus (Rat),"cellular response to growth factor stimulus [GO:0071363]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp135624_c0_seq2,551,35.9347,0.73336981,2,39,,2.00E-11,P59923,Zinc finger protein 445 (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15),Zinc finger protein 445 (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF13912;,,,,,,,,,ZN445_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp135624_c0_seq4,212,38.6792,0.63394268,0,259,,2.00E-16,Q13105,Zinc finger and BTB domain-containing protein 17 (Myc-interacting zinc finger protein 1) (Miz-1) (Zinc finger protein 151) (Zinc finger protein 60),Zinc finger and BTB domain-containing protein 17 (Myc-interacting zinc finger protein 1) (Miz-1) (Zinc finger protein 151) (Zinc finger protein 60),GO:0003677; GO:0006987; GO:0044267; GO:0007398; GO:0001702; GO:0046872; GO:0045786; GO:0005654; GO:0045893; GO:0003700; GO:0006351,"DNA binding; activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; ectoderm development; gastrulation with mouth forming second; metal ion binding; negative regulation of cell cycle; nucleoplasm; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT17_HUMAN,Homo sapiens (Human),"ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell cycle [GO:0045786]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitophagy [GO:1903146]; transcription, DNA-templated [GO:0006351]" comp135624_c0_seq5,209,38.756,0.77397349,10,122,,2.00E-12,Q6XDT4,Ikaros family zinc finger protein (Ikaros-like transcription factor) (OIL),Ikaros family zinc finger protein (Ikaros-like transcription factor) (OIL),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,IKZF_OIKDI,Oikopleura dioica (Tunicate),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135624_c0_seq6,284,36.2676,0.42986958,0,8,,4.00E-20,A6NJL1,Zinc finger and SCAN domain-containing protein 5B,Zinc finger and SCAN domain-containing protein 5B,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF02023;PF00096;PF13912;,,,,,,,,,ZSA5B_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp135624_c0_seq8,237,35.443,0.94930465,0,0,,5.00E-13,Q15940,Putative zinc finger protein 726P1,Putative zinc finger protein 726P1,GO:0046872; GO:0003676,metal ion binding; nucleic acid binding,PF00096;,,,,,,,,,ZNF67_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]" comp135624_c3_seq1,767,33.3768,0.7032979,18,93,,4.00E-60,Q61116,Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93),Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,3.00E-13,ruditapes_c21757,,,,,ZN235_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135625_c1_seq1,322,43.4783,0.54619001,1,37,,3.00E-10,Q80U35,Rho guanine nucleotide exchange factor 17,Rho guanine nucleotide exchange factor 17,GO:0005089; GO:0030036; GO:0035023,Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; regulation of Rho protein signal transduction,PF00621;,,,,,,,,,ARHGH_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; regulation of Rho protein signal transduction [GO:0035023] comp135625_c2_seq1,2925,46.5641,0.49833079,0,0,,2.00E-180,O60271,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1),GO:0001669; GO:0007257; GO:0005829; GO:0016021; GO:0042692; GO:0090074; GO:0048471; GO:0030335; GO:0051149; GO:0045666; GO:0051260; GO:0042147; GO:0007283; GO:0051146,"acrosomal vesicle; activation of JUN kinase activity; cytosol; integral to membrane; muscle cell differentiation; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of muscle cell differentiation; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; spermatogenesis; striated muscle cell differentiation",PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP4_HUMAN,Homo sapiens (Human),"activation of JUN kinase activity [GO:0007257]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; spermatogenesis [GO:0007283]; striated muscle cell differentiation [GO:0051146]" comp135625_c2_seq10,2397,47.0171,0.48823575,0,0,,2.00E-100,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,8.00E-149,CHOYP_JIP4.4.4,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq11,2352,47.0663,0.48084994,0,0,,,,,,,,,4.00E-51,CHOYP_BRAFLDRAFT_117085.1.1,,,,,,,,, comp135625_c2_seq13,2525,47.2475,0.47342064,0,0,,1.00E-99,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq15,2570,47.1595,0.48077755,0,0,,,,,,,,,0,CHOYP_JIP4.1.4,,,,,,,,, comp135625_c2_seq16,2937,46.6122,0.49496539,0,0,,2.00E-178,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.4.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq17,2379,46.9945,0.48470163,0,0,,,,,,,,,4.00E-51,CHOYP_BRAFLDRAFT_117085.1.1,,,,,,,,, comp135625_c2_seq19,2385,46.9602,0.49168164,0,0,,,,,,,,,2.00E-98,CHOYP_JIP3.1.1,,,,,,,,, comp135625_c2_seq2,2701,46.3532,0.50989705,0,0,,2.00E-121,P34609,JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16),JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16),GO:0043194; GO:0043679; GO:0044297; GO:0005737; GO:0030421; GO:0019900; GO:0019894; GO:0040011; GO:0018991; GO:0048471; GO:0030159; GO:0046328; GO:0048489,axon initial segment; axon terminus; cell body; cytoplasm; defecation; kinase binding; kinesin binding; locomotion; oviposition; perinuclear region of cytoplasm; receptor signaling complex scaffold activity; regulation of JNK cascade; synaptic vesicle transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP_CAEEL,Caenorhabditis elegans,activation of JUN kinase activity [GO:0007257]; defecation [GO:0030421]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of JNK cascade [GO:0046328]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq21,2907,46.5428,0.49544205,0,0,,0,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,,,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq23,2898,46.6529,0.4948997,0,0,,2.00E-153,Q29EP6,JNK-interacting protein 3 (Protein sunday driver),JNK-interacting protein 3 (Protein sunday driver),GO:0000139; GO:0005078; GO:0008088; GO:0019894; GO:0019901; GO:0046328; GO:0030140; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; axon cargo transport; kinesin binding; protein kinase binding; regulation of JNK cascade; trans-Golgi network transport vesicle; vesicle-mediated transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP3_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq25,2880,46.5972,0.49279791,0,0,,0,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,,,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq26,2328,46.9502,0.48833931,0,0,,,,,,,,,4.00E-51,CHOYP_BRAFLDRAFT_117085.1.1,,,,,,,,, comp135625_c2_seq27,2683,46.366,0.50590608,0,0,,2.00E-148,Q29EP6,JNK-interacting protein 3 (Protein sunday driver),JNK-interacting protein 3 (Protein sunday driver),GO:0000139; GO:0005078; GO:0008088; GO:0019894; GO:0019901; GO:0046328; GO:0030140; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; axon cargo transport; kinesin binding; protein kinase binding; regulation of JNK cascade; trans-Golgi network transport vesicle; vesicle-mediated transport,PF16471;PF09744;,3.00E-79,CHOYP_JIP4.2.4,,,,,,,JIP3_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq28,2531,47.175,0.48083815,0,0,,6.00E-101,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq29,2868,46.5481,0.49571684,0,0,,0,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.3.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq3,2752,46.4026,0.50569943,0,0,,3.00E-134,Q29EP6,JNK-interacting protein 3 (Protein sunday driver),JNK-interacting protein 3 (Protein sunday driver),GO:0000139; GO:0005078; GO:0008088; GO:0019894; GO:0019901; GO:0046328; GO:0030140; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; axon cargo transport; kinesin binding; protein kinase binding; regulation of JNK cascade; trans-Golgi network transport vesicle; vesicle-mediated transport,PF16471;PF09744;,3.00E-79,CHOYP_JIP4.4.4,,,,,,,JIP3_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq31,2695,46.3822,0.50361022,0,0,,4.00E-180,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.2.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq32,2340,47.0085,0.48430559,0,0,,,,,,,,,4.00E-51,CHOYP_BRAFLDRAFT_117085.1.1,,,,,,,,, comp135625_c2_seq35,2594,47.2629,0.47413951,0,0,,,,,,,,,1.00E-90,CHOYP_JIP3.1.1,,,,,,,,, comp135625_c2_seq36,2734,46.3789,0.50319838,0,0,,2.00E-179,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq38,2725,46.4587,0.50296735,0,0,,,,,,,,,3.00E-79,CHOYP_JIP4.2.4,,,,,,,,, comp135625_c2_seq39,2340,47.0085,0.4848346,0,0,,5.00E-100,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq42,2740,46.3504,0.50939773,0,0,,2.00E-179,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-98,CHOYP_JIP3.1.1,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq43,2582,47.2115,0.47767257,0,0,,,,,,,,,0,CHOYP_JIP4.1.4,,,,,,,,, comp135625_c2_seq44,2722,46.3262,0.50636597,0,0,,2.00E-162,Q9GQF1,JNK-interacting protein 3 (Protein sunday driver),JNK-interacting protein 3 (Protein sunday driver),GO:0000139; GO:0005078; GO:0008088; GO:0019901; GO:0046328; GO:0030140; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; axon cargo transport; protein kinase binding; regulation of JNK cascade; trans-Golgi network transport vesicle; vesicle-mediated transport,PF16471;PF09744;,3.00E-79,CHOYP_JIP4.4.4,,,,,,,JIP3_DROME,Drosophila melanogaster (Fruit fly),activation of JUN kinase activity [GO:0007257]; axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; sensory perception of pain [GO:0019233]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq45,2886,46.5696,0.49864297,0,0,,0,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,,,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq47,2713,46.4431,0.50577977,0,0,,,,,,,,,3.00E-85,CHOYP_LOC100374908.1.1,,,,,,,,, comp135625_c2_seq48,2734,46.3789,0.50266249,0,0,,,,,,,,,3.00E-79,CHOYP_JIP4.4.4,,,,,,,,, comp135625_c2_seq50,2513,47.1548,0.47745723,0,0,,2.00E-142,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq51,2543,47.2277,0.47720752,0,0,,,,,,,,,1.00E-90,CHOYP_JIP3.1.1,,,,,,,,, comp135625_c2_seq53,2949,46.6599,0.49212099,0,0,,,,,,,,,3.00E-79,CHOYP_JIP4.2.4,,,,,,,,, comp135625_c2_seq56,2937,46.6122,0.49545336,0,0,,2.00E-180,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.4.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq57,2358,47.0314,0.48842515,0,0,,3.00E-102,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq59,2695,46.3822,0.50305814,0,0,,1.00E-178,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.2.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq6,2910,46.6667,0.49234408,0,0,,3.00E-179,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.4.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq60,2764,46.4544,0.50257545,0,0,,4.00E-134,Q29EP6,JNK-interacting protein 3 (Protein sunday driver),JNK-interacting protein 3 (Protein sunday driver),GO:0000139; GO:0005078; GO:0008088; GO:0019894; GO:0019901; GO:0046328; GO:0030140; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; axon cargo transport; kinesin binding; protein kinase binding; regulation of JNK cascade; trans-Golgi network transport vesicle; vesicle-mediated transport,PF16471;PF09744;,,,,,,,,,JIP3_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq61,2346,46.9736,0.49192559,0,0,,2.00E-86,P34609,JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16),JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16),GO:0043194; GO:0043679; GO:0044297; GO:0005737; GO:0030421; GO:0019900; GO:0019894; GO:0040011; GO:0018991; GO:0048471; GO:0030159; GO:0046328; GO:0048489,axon initial segment; axon terminus; cell body; cytoplasm; defecation; kinase binding; kinesin binding; locomotion; oviposition; perinuclear region of cytoplasm; receptor signaling complex scaffold activity; regulation of JNK cascade; synaptic vesicle transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP_CAEEL,Caenorhabditis elegans,activation of JUN kinase activity [GO:0007257]; defecation [GO:0030421]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of JNK cascade [GO:0046328]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq62,2919,46.5913,0.49256147,0,0,,0,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,3.00E-79,CHOYP_JIP4.4.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq63,2555,47.2798,0.47409867,0,0,,,,,,,,,4.00E-51,CHOYP_BRAFLDRAFT_117085.1.1,,,,,,,,, comp135625_c2_seq65,712,45.5056,0.68180214,0,0,,,,,,,,,1.00E-89,CHOYP_JIP3.1.1,,,,,,,,, comp135625_c2_seq66,2746,46.4312,0.49953424,0,0,,,,,,,,,3.00E-79,CHOYP_JIP4.2.4,,,,,,,,, comp135625_c2_seq68,2752,46.4026,0.50623475,0,0,,1.00E-178,O60271,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1),GO:0001669; GO:0007257; GO:0005829; GO:0016021; GO:0042692; GO:0090074; GO:0048471; GO:0030335; GO:0051149; GO:0045666; GO:0051260; GO:0042147; GO:0007283; GO:0051146,"acrosomal vesicle; activation of JUN kinase activity; cytosol; integral to membrane; muscle cell differentiation; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of muscle cell differentiation; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; spermatogenesis; striated muscle cell differentiation",PF16471;PF09744;,3.00E-85,CHOYP_LOC100374908.1.1,,,,,,,JIP4_HUMAN,Homo sapiens (Human),"activation of JUN kinase activity [GO:0007257]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; spermatogenesis [GO:0007283]; striated muscle cell differentiation [GO:0051146]" comp135625_c2_seq69,2543,47.2277,0.47768898,0,0,,8.00E-102,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq7,2564,47.2309,0.47346895,0,0,,6.00E-98,Q9UPT6,C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3),GO:0000139; GO:0005078; GO:0007257; GO:0030673; GO:0007411; GO:0030425; GO:0030900; GO:0001701; GO:0019894; GO:0048286; GO:0060425; GO:0009791; GO:0019901; GO:0008104; GO:0046328; GO:0010468; GO:0007585; GO:0005790; GO:0016192,Golgi membrane; MAP-kinase scaffold activity; activation of JUN kinase activity; axolemma; axon guidance; dendrite; forebrain development; in utero embryonic development; kinesin binding; lung alveolus development; lung morphogenesis; post-embryonic development; protein kinase binding; protein localization; regulation of JNK cascade; regulation of gene expression; respiratory gaseous exchange; smooth endoplasmic reticulum; vesicle-mediated transport,PF16471;PF09744;,,,,,,,,,JIP3_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192] comp135625_c2_seq70,2525,47.2079,0.4738243,0,0,,,,,,,,,4.00E-51,CHOYP_BRAFLDRAFT_117085.1.1,,,,,,,,, comp135625_c2_seq71,2713,46.4062,0.50613639,0,0,,6.00E-178,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,,,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135625_c2_seq72,724,45.7182,0.66348322,0,0,,,,,,,,,3.00E-78,CHOYP_LOC100374908.1.1,,,,,,,,, comp135625_c2_seq73,2397,47.0171,0.48772373,0,0,,,,,,,,,1.00E-90,CHOYP_JIP3.1.1,,,,,,,,, comp135625_c2_seq9,2880,46.5972,0.49229599,0,0,,7.00E-180,Q58A65,C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9),GO:0008432; GO:0007257; GO:0000187; GO:0005829; GO:0019894; GO:0048273; GO:0090074; GO:0048471; GO:0030335; GO:0045666; GO:0051260; GO:0042147; GO:0051146,"JUN kinase binding; activation of JUN kinase activity; activation of MAPK activity; cytosol; kinesin binding; mitogen-activated protein kinase p38 binding; negative regulation of protein homodimerization activity; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of neuron differentiation; protein homooligomerization; retrograde transport, endosome to Golgi; striated muscle cell differentiation",PF16471;PF09744;,0,CHOYP_JIP4.1.4,,,,,,,JIP4_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" comp135626_c0_seq1,1988,35.8149,0.39304893,0,0,,9.00E-34,Q4KM95,Leucine-rich repeat-containing protein 42,Leucine-rich repeat-containing protein 42,,,PF13516;,,,,,,,,,LRC42_RAT,Rattus norvegicus (Rat), comp135632_c0_seq1,923,36.5114,1.01538581,0,0,,3.00E-22,F7J220,Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),GO:0030659; GO:0045087; GO:0016021; GO:0006909; GO:0005044,cytoplasmic vesicle membrane; innate immune response; integral to membrane; phagocytosis; scavenger receptor activity,PF00530;PF00084;,,,,,,,,,SRCR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),innate immune response [GO:0045087]; phagocytosis [GO:0006909] comp135632_c0_seq2,1000,37,0.95061823,9,145,,3.00E-18,Q14DK5,HHIP-like protein 1,HHIP-like protein 1,GO:0005975; GO:0005576; GO:0016020; GO:0016901; GO:0048038; GO:0005044,"carbohydrate metabolic process; extracellular region; membrane; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; quinone binding; scavenger receptor activity",PF03024;PF07995;PF00530;,,,,,,,,,HIPL1_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975] comp135632_c0_seq5,941,37.1945,1.0658603,0,0,,1.00E-21,Q96JK4,HHIP-like protein 1,HHIP-like protein 1,GO:0005975; GO:0005576; GO:0016020; GO:0016901; GO:0048038; GO:0005044,"carbohydrate metabolic process; extracellular region; membrane; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; quinone binding; scavenger receptor activity",PF03024;PF07995;PF00530;,,,,,,,,,HIPL1_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975] comp135632_c0_seq7,982,36.2525,0.93833622,0,0,,4.00E-21,Q60754,Macrophage receptor MARCO (Macrophage receptor with collagenous structure),Macrophage receptor MARCO (Macrophage receptor with collagenous structure),GO:0043277; GO:0005581; GO:0045087; GO:0016021; GO:0005886; GO:0005044,apoptotic cell clearance; collagen; innate immune response; integral to membrane; plasma membrane; scavenger receptor activity,PF01391;PF00530;,,,,,,,,,MARCO_MOUSE,Mus musculus (Mouse),apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898] comp135634_c0_seq1,977,38.6899,0.4205853,72,380,,1.00E-54,A0JMH2,UPF0565 protein C2orf69 homolog,UPF0565 protein C2orf69 homolog,GO:0005576,extracellular region,PF10561;,,,,,,,,,CB069_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp135635_c0_seq1,2033,43.4333,0.49381695,24,41,,0,Q7ZUQ3,Serine/threonine-protein kinase 3 (EC 2.7.11.1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)],Serine/threonine-protein kinase 3 (EC 2.7.11.1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)],GO:0005524; GO:0006915; GO:0005737; GO:0035329; GO:0046872; GO:0005634; GO:0004674,ATP binding; apoptotic process; cytoplasm; hippo signaling cascade; metal ion binding; nucleus; protein serine/threonine kinase activity,PF11629;PF00069;,,,,,,,,,STK3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; hippo signaling [GO:0035329] comp135635_c0_seq2,1729,45.5176,0.51890993,11,6,,0,O54748,Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)],Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)],GO:0005524; GO:0006915; GO:0005737; GO:0035329; GO:0046872; GO:0005634; GO:0004674,ATP binding; apoptotic process; cytoplasm; hippo signaling cascade; metal ion binding; nucleus; protein serine/threonine kinase activity,PF11629;PF00069;,0,CHOYP_LOC100168569.1.2,,,,,,,STK3_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; hippo signaling [GO:0035329]; protein phosphorylation [GO:0006468] comp135636_c1_seq3,938,29.6375,1.1347743,46,278,,,,,,,,,,,4.00E-12,ruditapes_c6976,,,,,,, comp135638_c0_seq1,1766,43.5447,0.53969946,528,386,,0,P38024,Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)],Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)],GO:0006189; GO:0034023; GO:0005524; GO:0005829; GO:0004638; GO:0004639; GO:0006144,'de novo' IMP biosynthetic process; 5-(carboxyamino)imidazole ribonucleotide mutase activity; ATP binding; cytosol; phosphoribosylaminoimidazole carboxylase activity; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; purine nucleobase metabolic process,PF00731;PF01259;,2.00E-168,CHOYP_BRAFLDRAFT_117612.1.1,,,,,,,PUR6_CHICK,Gallus gallus (Chicken),'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084] comp135650_c0_seq2,776,45.1031,0.52279313,18,313,,1.00E-50,Q99J23,GH3 domain-containing protein,GH3 domain-containing protein,GO:0005783; GO:0005635,endoplasmic reticulum; nuclear envelope,PF03321;,2.00E-48,CHOYP_BRAFLDRAFT_63587.1.2,,,,,,,GHDC_MOUSE,Mus musculus (Mouse), comp135652_c1_seq1,1107,43.8121,0.73647672,0,0,,1.00E-25,Q15935,Zinc finger protein 77 (ZNFpT1),Zinc finger protein 77 (ZNFpT1),GO:0003677; GO:0005737; GO:0046872; GO:0005730; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF77_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135652_c1_seq2,1670,41.3174,0.71637789,36,117,,2.00E-27,Q6ZMW2,Zinc finger protein 782,Zinc finger protein 782,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,1.00E-50,CHOYP_ZNF99.2.3,,,,,,,ZN782_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135653_c0_seq1,1011,40.1583,0.62765201,157,551,,4.00E-62,O75618,Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1),Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1),GO:0003677; GO:0005737; GO:0046697; GO:0008625; GO:0042177; GO:0045892; GO:0005730; GO:0042981; GO:0007283; GO:0006351,"DNA binding; cytoplasm; decidualization; extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of protein catabolic process; negative regulation of transcription, DNA-dependent; nucleolus; regulation of apoptotic process; spermatogenesis; transcription, DNA-dependent",PF01335;,7.00E-25,CHOYP_DEDD.1.1,,,,,,,DEDD_HUMAN,Homo sapiens (Human),"decidualization [GO:0046697]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901837]; regulation of apoptotic process [GO:0042981]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp135655_c0_seq1,1576,37.5635,0.57725944,1898,11,male>female,,,,,,,,,,9.00E-74,ruditapes_c28391,,,,,,, comp135656_c7_seq3,798,40.1003,0.37140863,49,122,,3.00E-07,Q96D05,Uncharacterized protein C10orf35,Uncharacterized protein C10orf35,GO:0016021,integral to membrane,PF15378;,,,,,,,,,CJ035_HUMAN,Homo sapiens (Human), comp135661_c3_seq1,832,44.351,0.37079405,34,59,,1.00E-33,Q9DAZ9,Zinc finger FYVE domain-containing protein 19,Abscission/NoCut checkpoint regulator (ANCHR) (Zinc finger FYVE domain-containing protein 19),GO:0008270,zinc ion binding,PF01363;,5.00E-25,CHOYP_LOC591968.1.1,,,,,,,ZFY19_MOUSE,Mus musculus (Mouse),abscission [GO:0009838]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of cytokinesis [GO:0032466] comp135662_c0_seq1,1308,45.107,0.70217829,34,212,,2.00E-88,P55196,Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6),GO:0034332; GO:0045177; GO:0007155; GO:0034329; GO:0005913; GO:0005911; GO:0007267; GO:0005829; GO:0005634; GO:0005886; GO:0008022; GO:0007165,adherens junction organization; apical part of cell; cell adhesion; cell junction assembly; cell-cell adherens junction; cell-cell junction; cell-cell signaling; cytosol; nucleus; plasma membrane; protein C-terminus binding; signal transduction,PF01843;PF00498;PF00595;PF00788;,1.00E-118,CHOYP_BRAFLDRAFT_208117.3.3,4.00E-96,ruditapes2_c1590,,,,,AFAD_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp135663_c0_seq1,1888,36.9174,0.79381542,1231,416,,9.00E-40,B6CZ61,Leucine-rich repeat-containing protein 51 (Protein LRTOMT1),Leucine-rich repeat-containing protein 51 (Protein LRTOMT1),GO:0005737,cytoplasm,,,,,,,,,,LRC51_RAT,Rattus norvegicus (Rat), comp135666_c1_seq1,979,41.7773,0.4260874,45,293,,3.00E-72,Q6P0I8,Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog),Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog),GO:0003723; GO:0005737; GO:0000178; GO:0005730; GO:0006364,RNA binding; cytoplasm; exosome (RNase complex); nucleolus; rRNA processing,PF01138;,,,,,,,,,EXOS6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475]" comp135666_c1_seq2,930,43.1183,0.34874179,0,22,,9.00E-64,Q6P0I8,Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog),Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog),GO:0003723; GO:0005737; GO:0000178; GO:0005730; GO:0006364,RNA binding; cytoplasm; exosome (RNase complex); nucleolus; rRNA processing,PF01138;,7.00E-56,CHOYP_LOC100369488.1.1,,,,,,,EXOS6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475]" comp135669_c0_seq1,960,39.375,0.24366152,216,864,,6.00E-48,Q66JD1,ATP synthase mitochondrial F1 complex assembly factor 1,ATP synthase mitochondrial F1 complex assembly factor 1,GO:0005739; GO:0006461,mitochondrion; protein complex assembly,PF06644;,,,1.00E-31,ruditapes_c21779,,,,,ATPF1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615] comp135670_c0_seq1,1736,39.2281,0.51272763,282,1222,,9.00E-159,P06766,DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-),DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-),GO:0071897; GO:0006260; GO:0003887; GO:0006287; GO:0008219; GO:0005737; GO:0003684; GO:0016829; GO:0046872; GO:0043066; GO:0005634; GO:0006290; GO:0045471; GO:0005876,"DNA biosynthetic process; DNA replication; DNA-directed DNA polymerase activity; base-excision repair, gap-filling; cell death; cytoplasm; damaged DNA binding; lyase activity; metal ion binding; negative regulation of apoptotic process; nucleus; pyrimidine dimer repair; response to ethanol; spindle microtubule",PF14792;PF14791;PF10391;PF14716;,1.00E-126,CHOYP_DPOLB.1.1,,,,,,,DPOLB_RAT,Rattus norvegicus (Rat),"aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]" comp135677_c0_seq1,2605,40.5758,0.57828958,155,130,,4.00E-114,Q14186,Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1),Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1),GO:0003677; GO:0000082; GO:0008283; GO:0005654; GO:0045944; GO:0003700; GO:0003713; GO:0005667; GO:0006367; GO:0007179,DNA binding; G1/S transition of mitotic cell cycle; cell proliferation; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription factor complex; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway,PF08781;PF02319;,2.00E-150,CHOYP_LOC594176.1.1,,,,,,,TFDP1_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135679_c0_seq1,1914,42.4765,0.49972705,389,3152,,0,P58545,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,1.00E-171,CHOYP_BTBD3.1.3,,,,,,,BTBD3_MOUSE,Mus musculus (Mouse),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813] comp135681_c1_seq1,2051,39.3954,0.62767586,0,0,,8.00E-17,A1D4K4,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,,,,,,,,,PABP_NEOFI,Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp135681_c1_seq2,2033,39.2523,0.61255261,0,0,,2.00E-23,B3M3R5,Protein alan shepard,Protein alan shepard,GO:0003723; GO:0000166; GO:0009629,RNA binding; nucleotide binding; response to gravity,PF00076;,,,,,,,,,SHEP_DROAN,Drosophila ananassae (Fruit fly),response to gravity [GO:0009629] comp135681_c1_seq3,2340,39.1453,0.67374148,7,20,,1.00E-19,Q4VXU2,Polyadenylate-binding protein 1-like,Polyadenylate-binding protein 1-like,GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00658;PF00076;,,,,,,,,,PAP1L_HUMAN,Homo sapiens (Human),mRNA polyadenylation [GO:0006378]; oocyte maturation [GO:0001556] comp135681_c1_seq4,2017,39.5141,0.63454248,0,0,,6.00E-17,A2Q848,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0005622; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; intracellular; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,,,,,,,,,PABP_ASPNC,Aspergillus niger (strain CBS 513.88 / FGSC A1513),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp135681_c1_seq5,2322,39.0181,0.66103383,50,55,,3.00E-49,Q28GD4,ELAV-like protein 2 (Protein ElrB),ELAV-like protein 2 (Protein ElrB),GO:0003723; GO:0005938; GO:0007275; GO:0000166; GO:0030529,RNA binding; cell cortex; multicellular organismal development; nucleotide binding; ribonucleoprotein complex,PF00076;,,,,,,,,,ELAV2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),multicellular organism development [GO:0007275] comp135681_c1_seq6,1999,39.3697,0.61939104,0,0,,5.00E-69,O09032,ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),GO:0017091; GO:0000166,AU-rich element binding; nucleotide binding,PF00076;,,,,,,,,,ELAV4_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; associative learning [GO:0008306]; cellular response to nerve growth factor stimulus [GO:1990090]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; positive regulation of dendrite development [GO:1900006]; regeneration [GO:0031099]; regulation of mRNA stability [GO:0043488]; response to cocaine [GO:0042220]; response to endoplasmic reticulum stress [GO:0034976] comp135683_c0_seq1,958,39.3528,0.99601978,29,472,,2.00E-28,Q9NV35,"Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)","Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)",GO:0035539; GO:0008413; GO:0006184; GO:0005829; GO:0006203; GO:0046872; GO:0034656,"8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; GTP catabolic process; cytosol; dGTP catabolic process; metal ion binding; nucleobase-containing small molecule catabolic process",PF00293;,,,,,,,,,NUD15_HUMAN,Homo sapiens (Human),dGTP catabolic process [GO:0006203]; nucleobase-containing small molecule catabolic process [GO:0034656] comp135691_c0_seq1,605,39.6694,0.25250069,0,0,,2.00E-48,Q9ZT48,Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1),Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) (AtATE1) (Protein DELAYED-LEAF-SENESCENCE 1),GO:0004057; GO:0010150; GO:0016598; GO:0050994; GO:0010029; GO:0009737,arginyltransferase activity; leaf senescence; protein arginylation; regulation of lipid catabolic process; regulation of seed germination; response to abscisic acid stimulus,PF04377;PF04376;,,,,,,,,,ATE1_ARATH,Arabidopsis thaliana (Mouse-ear cress),leaf senescence [GO:0010150]; protein arginylation [GO:0016598]; regulation of lipid catabolic process [GO:0050994]; regulation of seed germination [GO:0010029]; response to abscisic acid [GO:0009737] comp135691_c0_seq2,2029,38.2454,0.29789427,1,0,,1.00E-134,O95260,Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1),Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1),GO:0004057; GO:0005737; GO:0005634; GO:0016598,arginyltransferase activity; cytoplasm; nucleus; protein arginylation,PF04377;PF04376;,,,,,,,,,ATE1_HUMAN,Homo sapiens (Human),protein arginylation [GO:0016598] comp135691_c0_seq3,1319,36.2396,0.28037399,1,0,,1.00E-34,Q55EI0,Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1),Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1),GO:0004057; GO:0016598,arginyltransferase activity; protein arginylation,PF04377;PF04376;,6.00E-40,CHOYP_ATE1.2.3,,,,,,,ATE1_DICDI,Dictyostelium discoideum (Slime mold),protein arginylation [GO:0016598] comp135691_c0_seq4,1261,41.3164,0.2976066,0,0,,5.00E-13,A7H303,Putative arginyl-tRNA--protein transferase (Arginyltransferase) (R-transferase) (EC 2.3.2.8),Putative arginyl-tRNA--protein transferase (Arginyltransferase) (R-transferase) (EC 2.3.2.8),GO:0004057; GO:0005737; GO:0016598,arginyltransferase activity; cytoplasm; protein arginylation,PF04377;PF04376;,,,,,,,,,ATE_CAMJD,Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97),protein arginylation [GO:0016598] comp135694_c0_seq1,650,39.5385,0.42119665,0,3,,1.00E-25,P0DKL9,ARL14 effector protein-like,ARL14 effector protein-like,,,PF14949;,3.00E-33,CHOYP_BRAFLDRAFT_124346.2.2,,,,,,,A14EL_HUMAN,Homo sapiens (Human), comp135694_c0_seq2,1077,39.9257,0.62382925,25,55,,4.00E-26,Q5FVK8,ARL14 effector protein (ARF7 effector protein),ARL14 effector protein (ARF7 effector protein),GO:0005737,cytoplasm,PF14949;,,,,,,,,,AL14E_RAT,Rattus norvegicus (Rat), comp135696_c0_seq1,2100,29.6667,0.3491629,4605,23147,,8.00E-29,O96952,Thioredoxin (Trx),Thioredoxin (Trx),GO:0045454; GO:0005737; GO:0006662; GO:0015035,cell redox homeostasis; cytoplasm; glycerol ether metabolic process; protein disulfide oxidoreductase activity,PF00085;,8.00E-28,CHOYP_CAOG_02925.1.1,1.00E-17,ruditapes2_c857,,,,,THIO_GEOCY,Geodia cydonium (Sponge),cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662] comp135697_c5_seq1,1752,46.8037,0.47954423,251,232,,0,P16332,"Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase)","Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase)",GO:0031419; GO:0050667; GO:0046872; GO:0004494; GO:0005759; GO:0005739; GO:0072341; GO:0009791,cobalamin binding; homocysteine metabolic process; metal ion binding; methylmalonyl-CoA mutase activity; mitochondrial matrix; mitochondrion; modified amino acid binding; post-embryonic development,PF02310;PF01642;,0,CHOYP_MUTA.1.1,,,,,,,MUTA_MOUSE,Mus musculus (Mouse),homocysteine metabolic process [GO:0050667]; post-embryonic development [GO:0009791] comp135698_c0_seq2,788,38.3249,0.20917319,79,365,,1.00E-20,Q7Z6J9,tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54),tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54),GO:0006397; GO:0005730; GO:0006388,"mRNA processing; nucleolus; tRNA splicing, via endonucleolytic cleavage and ligation",PF12928;,,,,,,,,,SEN54_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379]" comp135698_c0_seq3,980,39.2857,0.25370716,55,141,,1.00E-09,O74908,Probable tRNA-splicing endonuclease subunit sen54 (tRNA-intron endonuclease sen54),Probable tRNA-splicing endonuclease subunit sen54 (tRNA-intron endonuclease sen54),GO:0005741; GO:0000214; GO:0000379,mitochondrial outer membrane; tRNA-intron endonuclease complex; tRNA-type intron splice site recognition and cleavage,PF12928;,2.00E-30,CHOYP_LOC100702975.1.1,,,,,,,SEN54_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA-type intron splice site recognition and cleavage [GO:0000379]" comp135701_c1_seq1,1136,36.4437,0.50844984,4,0,,2.00E-11,Q08DV6,Ankyrin repeat and SOCS box protein 3 (ASB-3),Ankyrin repeat and SOCS box protein 3 (ASB-3),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB3_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556] comp135701_c1_seq3,1713,33.0998,0.48271817,46,25,,2.00E-15,Q8WXK3,Ankyrin repeat and SOCS box protein 13 (ASB-13),Ankyrin repeat and SOCS box protein 13 (ASB-13),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB13_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp135706_c0_seq1,1783,39.484,0.23111809,27,372,,3.00E-125,A5PKG6,Ubiquitin conjugation factor E4 A,Ubiquitin conjugation factor E4 A (EC 6.3.2.-),GO:0000151; GO:0006511; GO:0034450,ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-ubiquitin ligase activity,PF04564;PF10408;,3.00E-95,CHOYP_UBE4A.2.2,,,,,,,UBE4A_BOVIN,Bos taurus (Bovine),protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] comp135707_c0_seq2,1084,34.2251,0.44285752,36,14,,3.00E-24,E7EYQ9,Transmembrane protein 216,Transmembrane protein 216,GO:0042384; GO:0005737; GO:0016021; GO:0005932,cilium assembly; cytoplasm; integral to membrane; microtubule basal body,PF09799;,7.00E-44,CHOYP_LOC591901.3.3,,,,,,,TM216_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384] comp135707_c0_seq4,1231,32.6564,0.79444497,51,372,,1.00E-34,Q6NT55,Cytochrome P450 4F22 (EC 1.14.14.-),Cytochrome P450 4F22 (EC 1.14.14.-),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,9.00E-12,CHOYP_BRAFLDRAFT_61250.13.14,,,,,,,CP4FN_HUMAN,Homo sapiens (Human),icosanoid metabolic process [GO:0006690] comp135707_c1_seq1,439,43.0524,0.65192953,9,62,,1.00E-29,P08516,Cytochrome P450 4A10 (CYPIVA10) (Cytochrome P450-LA-omega 1) (Cytochrome P452) (Lauric acid omega-hydroxylase) (EC 1.14.15.3),"Cytochrome P450 4A10 (CYPIVA10) (Cytochrome P450-LA-omega 1) (Cytochrome P452) (Lauric acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.13.205) [Cleaved into: Cytochrome P450 4A10, N-terminally processed]",GO:0018685; GO:0019369; GO:0008391; GO:0052869; GO:0005789; GO:0020037; GO:0046456; GO:0043231; GO:0005506; GO:0001822; GO:0048252; GO:0043651; GO:0001890,alkane 1-monooxygenase activity; arachidonic acid metabolic process; arachidonic acid monooxygenase activity; arachidonic acid omega-hydroxylase activity; endoplasmic reticulum membrane; heme binding; icosanoid biosynthetic process; intracellular membrane-bounded organelle; iron ion binding; kidney development; lauric acid metabolic process; linoleic acid metabolic process; placenta development,PF00067;,,,,,,,,,CP4AA_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369]; icosanoid biosynthetic process [GO:0046456]; kidney development [GO:0001822]; lauric acid metabolic process [GO:0048252]; linoleic acid metabolic process [GO:0043651]; placenta development [GO:0001890] comp135712_c0_seq1,1054,38.8046,0.25413137,167,1746,,4.00E-40,Q5K2N1,Steroid 5-alpha-reductase DET2 (LeDET2) (EC 1.3.1.22),Steroid 5-alpha-reductase DET2 (LeDET2) (EC 1.3.1.22),GO:0003865; GO:0016132; GO:0047751; GO:0005737; GO:0016021; GO:0050213,3-oxo-5-alpha-steroid 4-dehydrogenase activity; brassinosteroid biosynthetic process; cholestenone 5-alpha-reductase activity; cytoplasm; integral to membrane; progesterone 5-alpha-reductase activity,PF02544;,7.00E-25,CHOYP_LOC100888209.1.1,,,,,,,DET2_SOLLC,Solanum lycopersicum (Tomato) (Lycopersicon esculentum),brassinosteroid biosynthetic process [GO:0016132]; oxidation-reduction process [GO:0055114] comp135714_c0_seq1,1721,36.5485,0.52287467,141,362,,2.00E-89,Q9H0P0,Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36),Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36),GO:0008665; GO:0008253; GO:0005829; GO:0005783; GO:0000287; GO:0005739; GO:0000166; GO:0009117; GO:0006206; GO:0046135,2'-phosphotransferase activity; 5'-nucleotidase activity; cytosol; endoplasmic reticulum; magnesium ion binding; mitochondrion; nucleotide binding; nucleotide metabolic process; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process,PF05822;,,,,,,,,,5NT3_HUMAN,Homo sapiens (Human),adenosine metabolic process [GO:0046085]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213] comp135714_c0_seq2,1450,35.8621,0.47266665,9,33,,,,,,,,,4.00E-36,CHOYP_5NT3.1.1,,,,,,,,, comp135718_c0_seq5,481,40.9563,0.74536405,3,16,,2.00E-16,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp135718_c0_seq6,351,38.4615,0.85024845,0,0,,4.00E-16,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp135728_c1_seq1,1277,35.1605,0.10228098,167,379,,6.00E-25,Q9D1C2,"Protein chibby homolog 1 (Cytosolic leucine-rich protein) (PIGEA-14) (PKD2 interactor, Golgi and endoplasmic reticulum-associated 1)","Protein chibby homolog 1 (Cytosolic leucine-rich protein) (PIGEA-14) (PKD2 interactor, Golgi and endoplasmic reticulum-associated 1)",GO:0005794; GO:0055007; GO:0042384; GO:0045444; GO:0005932; GO:0090090; GO:0045892; GO:0016607; GO:0008104; GO:0005802,"Golgi apparatus; cardiac muscle cell differentiation; cilium assembly; fat cell differentiation; microtubule basal body; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of transcription, DNA-dependent; nuclear speck; protein localization; trans-Golgi network",PF14645;,3.00E-43,CHOYP_BRAFLDRAFT_59498.2.2,,,,,,,CBY1_MOUSE,Mus musculus (Mouse),"cardiac muscle cell differentiation [GO:0055007]; cilium assembly [GO:0042384]; fat cell differentiation [GO:0045444]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; protein localization [GO:0008104]" comp135730_c0_seq1,1033,38.0445,0.40568149,149,506,,9.00E-95,Q95044,Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C),Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C),GO:0005524; GO:0051301; GO:0007067; GO:0004842,ATP binding; cell division; mitosis; ubiquitin-protein ligase activity,PF00179;,5.00E-77,CHOYP_UBE2C.1.1,,,,,,,UBE2C_SPISO,Spisula solidissima (Atlantic surf-clam),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp135733_c0_seq1,1090,47.3394,0.51762391,40,214,,9.00E-23,Q3SZU0,Gametocyte-specific factor 1 (Protein FAM112B),Gametocyte-specific factor 1 (Protein FAM112B),GO:0046872,metal ion binding,PF05253;,5.00E-27,CHOYP_BRAFLDRAFT_124130.2.3,,,,,,,GTSF1_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] comp135734_c1_seq2,1097,33.2726,0.42929359,30,76,,1.00E-09,A0JNB1,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135734_c1_seq7,1013,35.0444,0.29188284,0,0,,8.00E-12,Q86WZ6,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135734_c1_seq8,1043,34.6117,0.29145755,3,0,,3.00E-13,A0JNB1,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135735_c3_seq1,902,38.9135,0.17632149,31,143,,2.00E-32,Q5ZID2,Programmed cell death protein 2-like,Programmed cell death protein 2-like,GO:0005737,cytoplasm,PF04194;,,,,,,,,,PDD2L_CHICK,Gallus gallus (Chicken), comp135738_c0_seq1,1131,39.3457,0.25772021,15,47,,2.00E-132,Q99MB4,COBW domain-containing protein 1 (Cobalamin synthase W domain-containing protein 1),COBW domain-containing protein 1 (Cobalamin synthase W domain-containing protein 1),GO:0005524,ATP binding,PF02492;PF07683;,8.00E-101,CHOYP_CBWD1.1.1,,,,,,,CBWD1_RAT,Rattus norvegicus (Rat), comp135738_c0_seq2,1214,38.6326,0.25051563,10,150,,6.00E-137,Q99MB4,COBW domain-containing protein 1 (Cobalamin synthase W domain-containing protein 1),COBW domain-containing protein 1 (Cobalamin synthase W domain-containing protein 1),GO:0005524,ATP binding,PF02492;PF07683;,,,,,,,,,CBWD1_RAT,Rattus norvegicus (Rat), comp135740_c1_seq2,1604,37.3441,0.41328946,26,70,,1.00E-24,P62501,TSC22 domain family protein 1 (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein),TSC22 domain family protein 1 (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein),GO:0005737; GO:0005634; GO:0003700; GO:0006351,"cytoplasm; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01166;,4.00E-37,CHOYP_TSC22D1.1.1,,,,,,,T22D1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp135743_c1_seq1,1010,34.1584,0.455943,110,22,,3.00E-09,Q8NEA4,F-box only protein 36,F-box only protein 36,,,PF00646;,,,,,,,,,FBX36_HUMAN,Homo sapiens (Human),SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp135744_c0_seq1,2404,41.4725,0.80691662,40,77,,4.00E-10,Q24423,Zinc finger protein Noc (Zinc finger protein NocA),Zinc finger protein Noc (Zinc finger protein NocA),GO:0003677; GO:0007219; GO:0007420; GO:0008283; GO:0002121; GO:0035218; GO:0046872; GO:0010629; GO:0005634; GO:0008056; GO:0006357; GO:0007430; GO:0035220,"DNA binding; Notch signaling pathway; brain development; cell proliferation; inter-male aggressive behavior; leg disc development; metal ion binding; negative regulation of gene expression; nucleus; ocellus development; regulation of transcription from RNA polymerase II promoter; terminal branching, open tracheal system; wing disc development",,,,,,,,,,NOC_DROME,Drosophila melanogaster (Fruit fly),"brain development [GO:0007420]; cell proliferation [GO:0008283]; compound eye photoreceptor fate commitment [GO:0001752]; eye-antennal disc development [GO:0035214]; inter-male aggressive behavior [GO:0002121]; leg disc development [GO:0035218]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; ocellus development [GO:0008056]; open tracheal system development [GO:0007424]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; terminal branching, open tracheal system [GO:0007430]; wing disc development [GO:0035220]" comp135744_c0_seq2,2188,40.7678,0.79618112,24,25,,8.00E-06,Q9VJS8,Zinc finger protein Elbow,Zinc finger protein Elbow,GO:0007219; GO:0008283; GO:0035214; GO:0048737; GO:0046872; GO:0010629; GO:0003676; GO:0005634; GO:0007424; GO:0035220,Notch signaling pathway; cell proliferation; eye-antennal disc development; imaginal disc-derived appendage development; metal ion binding; negative regulation of gene expression; nucleic acid binding; nucleus; open tracheal system development; wing disc development,,1.00E-26,CHOYP_NOC.1.1,,,,,,,ELBOW_DROME,Drosophila melanogaster (Fruit fly),cell proliferation [GO:0008283]; compound eye photoreceptor fate commitment [GO:0001752]; eye-antennal disc development [GO:0035214]; imaginal disc-derived appendage development [GO:0048737]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; open tracheal system development [GO:0007424]; wing disc development [GO:0035220] comp135745_c0_seq1,2802,43.4333,0.50723857,5,15,,1.00E-68,Q9QYE0,Zinc finger protein PLAG1 (Pleiomorphic adenoma gene 1 protein),Zinc finger protein PLAG1 (Pleiomorphic adenoma gene 1 protein),GO:0003677; GO:0022612; GO:0046872; GO:0035264; GO:0010629; GO:0005634; GO:0035265; GO:0010628; GO:0060252; GO:0060736; GO:0000981,DNA binding; gland morphogenesis; metal ion binding; multicellular organism growth; negative regulation of gene expression; nucleus; organ growth; positive regulation of gene expression; positive regulation of glial cell proliferation; prostate gland growth; sequence-specific DNA binding RNA polymerase II transcription factor activity,,3.00E-73,CHOYP_LOC100695438.1.1,,,1.00E-63,AM862973.p.cg.6,9,,PLAG1_MOUSE,Mus musculus (Mouse),gland morphogenesis [GO:0022612]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; organ growth [GO:0035265]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736] comp135745_c0_seq2,1546,43.7257,0.40659184,0,0,,2.00E-12,A2AJ77,PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),GO:0003677; GO:0046872; GO:0008168; GO:0022008; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; neurogenesis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD12_MOUSE,Mus musculus (Mouse),"neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135745_c0_seq3,2791,43.4253,0.50945165,17,17,,2.00E-27,P17019,Zinc finger protein 708 (Zinc finger protein 15) (Zinc finger protein 15-like 1) (Zinc finger protein KOX8),Zinc finger protein 708 (Zinc finger protein 15) (Zinc finger protein 15-like 1) (Zinc finger protein KOX8),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,1.00E-71,CHOYP_LOC100695438.1.1,,,,,,,ZN708_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135745_c0_seq4,2045,43.2274,0.43996631,0,0,,3.00E-21,Q5RAX9,PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10),PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;PF12171;,,,,,,,,,PRD10_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135746_c0_seq1,3154,42.8662,0.56321691,3,0,,2.00E-58,O94986,Centrosomal protein of 152 kDa (Cep152),Centrosomal protein of 152 kDa (Cep152),GO:0000086; GO:0005813; GO:0051298; GO:0005829; GO:0005634,G2/M transition of mitotic cell cycle; centrosome; centrosome duplication; cytosol; nucleus,,,,,,,,,,CE152_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; de novo centriole assembly [GO:0098535]; G2/M transition of mitotic cell cycle [GO:0000086] comp135746_c0_seq2,3503,41.1362,0.56141855,21,16,,,,,,,,,7.00E-12,CHOYP_CEP152.1.1,,,,,,,,, comp135752_c0_seq1,890,37.0787,0.46104434,0,9,,3.00E-11,Q5U2R4,Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),GO:0008168; GO:0000964; GO:0042645; GO:0008033,methyltransferase activity; mitochondrial RNA 5'-end processing; mitochondrial nucleoid; tRNA processing,PF01746;,,,,,,,,,MRRP1_RAT,Rattus norvegicus (Rat),mitochondrial RNA 5'-end processing [GO:0000964]; tRNA processing [GO:0008033] comp135752_c0_seq2,900,36.8889,0.46058406,3,11,,1.00E-17,Q7JUX9,Mitochondrial ribonuclease P protein 1 homolog (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),Mitochondrial ribonuclease P protein 1 homolog (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),GO:0008168; GO:0005739; GO:0008033,methyltransferase activity; mitochondrion; tRNA processing,PF01746;,,,,,,,,,MRRP1_DROME,Drosophila melanogaster (Fruit fly),tRNA processing [GO:0008033] comp135753_c0_seq1,1646,41.13,1.19177256,0,18,,7.00E-40,Q8BG58,Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),GO:0031418; GO:0005509; GO:0005789; GO:0016021; GO:0005506; GO:0016706,"L-ascorbic acid binding; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13640;PF13499;,,,,,,,,,P4HTM_MOUSE,Mus musculus (Mouse),regulation of erythrocyte differentiation [GO:0045646] comp135753_c0_seq2,1667,40.7918,1.19659897,3,89,,7.00E-12,Q5ZLK5,"Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)","Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)",GO:0031418; GO:0005788; GO:0005506; GO:0016702; GO:0004656,"L-ascorbic acid binding; endoplasmic reticulum lumen; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; procollagen-proline 4-dioxygenase activity",PF13640;PF08336;,,,,,,,,,P4HA2_CHICK,Gallus gallus (Chicken), comp135754_c0_seq1,542,43.3579,1.01110131,2,76,,2.00E-06,Q96Q42,Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein),Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein),GO:0017137; GO:0017112; GO:0030676; GO:0016601; GO:0005087; GO:0030424; GO:0007409; GO:0001662; GO:0008219; GO:0005813; GO:0005829; GO:0030425; GO:0043197; GO:0005769; GO:0016197; GO:0007032; GO:0030426; GO:0001701; GO:0030027; GO:0007626; GO:0016020; GO:0007528; GO:0048812; GO:0043025; GO:0005543; GO:0032855; GO:0035022; GO:0014069; GO:0043234; GO:0008104; GO:0043539; GO:0001881; GO:0032313; GO:0051036; GO:0006979; GO:0001726; GO:0035249; GO:0031982; GO:0016050,"Rab GTPase binding; Rab guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; Ran guanyl-nucleotide exchange factor activity; axon; axonogenesis; behavioral fear response; cell death; centrosome; cytosol; dendrite; dendritic spine; early endosome; endosomal transport; endosome organization; growth cone; in utero embryonic development; lamellipodium; locomotory behavior; membrane; neuromuscular junction development; neuron projection morphogenesis; neuronal cell body; phospholipid binding; positive regulation of Rac GTPase activity; positive regulation of Rac protein signal transduction; postsynaptic density; protein complex; protein localization; protein serine/threonine kinase activator activity; receptor recycling; regulation of Rab GTPase activity; regulation of endosome size; response to oxidative stress; ruffle; synaptic transmission, glutamatergic; vesicle; vesicle organization",PF02493;PF00415;PF00621;PF02204;,,,,,,,,,ALS2_HUMAN,Homo sapiens (Human),"axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Rac protein signal transduction [GO:0035022]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050]" comp135754_c0_seq2,691,49.3488,1.14175275,1,19,,2.00E-19,Q6PAV2,Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4),GO:0030154; GO:0005737; GO:0005829; GO:0005634; GO:0042787; GO:0007283; GO:0004842,cell differentiation; cytoplasm; cytosol; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity,PF00632;PF00415;,,,,,,,,,HERC4_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp135754_c0_seq3,826,48.7893,1.04917438,0,19,,3.00E-30,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,,,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp135759_c0_seq1,666,38.4384,0.94330902,0,0,,,,,,,,,3.00E-52,CHOYP_BRAFLDRAFT_266781.2.2,,,,,,,,, comp135759_c0_seq2,1214,40.939,0.89271197,33,57,,4.00E-128,P22129,Ras-related protein Rab-11B (ORA3),Ras-related protein Rab-11B (ORA3),GO:0019003; GO:0005525; GO:0003924; GO:0030054; GO:0071468; GO:0045054; GO:0035773; GO:0032402; GO:0045335; GO:0030670; GO:0001881; GO:0055038; GO:0045055; GO:0044070; GO:2001135; GO:2000008; GO:1990126; GO:0007264; GO:0008021; GO:0030672; GO:0033572,"GDP binding; GTP binding; GTPase activity; cell junction; cellular response to acidity; constitutive secretory pathway; insulin secretion involved in cellular response to glucose stimulus; melanosome transport; phagocytic vesicle; phagocytic vesicle membrane; receptor recycling; recycling endosome membrane; regulated secretory pathway; regulation of anion transport; regulation of endocytic recycling; regulation of protein localization to cell surface; retrograde transport, endosome to plasma membrane; small GTPase mediated signal transduction; synaptic vesicle; synaptic vesicle membrane; transferrin transport",PF00071;,5.00E-141,CHOYP_BRAFLDRAFT_266781.2.2,,,,,,,RB11B_DISOM,Diplobatis ommata (Ocellated electric ray) (Discopyge ommata),"cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]" comp135759_c0_seq4,1296,38.2716,0.71263779,2,0,,2.00E-88,P22129,Ras-related protein Rab-11B (ORA3),Ras-related protein Rab-11B (ORA3),GO:0019003; GO:0005525; GO:0003924; GO:0030054; GO:0071468; GO:0045054; GO:0035773; GO:0032402; GO:0045335; GO:0030670; GO:0001881; GO:0055038; GO:0045055; GO:0044070; GO:2001135; GO:2000008; GO:1990126; GO:0007264; GO:0008021; GO:0030672; GO:0033572,"GDP binding; GTP binding; GTPase activity; cell junction; cellular response to acidity; constitutive secretory pathway; insulin secretion involved in cellular response to glucose stimulus; melanosome transport; phagocytic vesicle; phagocytic vesicle membrane; receptor recycling; recycling endosome membrane; regulated secretory pathway; regulation of anion transport; regulation of endocytic recycling; regulation of protein localization to cell surface; retrograde transport, endosome to plasma membrane; small GTPase mediated signal transduction; synaptic vesicle; synaptic vesicle membrane; transferrin transport",PF00071;,,,,,,,,,RB11B_DISOM,Diplobatis ommata (Ocellated electric ray) (Discopyge ommata),"cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]" comp135760_c0_seq1,1000,38.9,0.31929856,163,540,,7.00E-53,P56213,FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration),FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration),GO:0050660; GO:0005758; GO:0005739; GO:0015035; GO:0016972,flavin adenine dinucleotide binding; mitochondrial intermembrane space; mitochondrion; protein disulfide oxidoreductase activity; thiol oxidase activity,PF04777;,,,,,,,,,ALR_MOUSE,Mus musculus (Mouse), comp135761_c0_seq1,861,36.3531,0.28328677,21,167,,1.00E-14,Q54XT8,Ribosomal RNA processing protein 36 homolog,Ribosomal RNA processing protein 36 homolog,GO:0005730; GO:0006364,nucleolus; rRNA processing,PF06102;,,,,,,,,,RRP36_DICDI,Dictyostelium discoideum (Slime mold),"cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp135761_c0_seq2,879,35.2673,0.19919443,14,35,,7.00E-27,A7SL20,Ribosomal RNA processing protein 36 homolog,Ribosomal RNA processing protein 36 homolog,GO:0005730; GO:0006364,nucleolus; rRNA processing,PF06102;,8.00E-17,CHOYP_WDR92.1.1,,,,,,,RRP36_NEMVE,Nematostella vectensis (Starlet sea anemone),"cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp135770_c1_seq1,1188,42.3401,0.3971405,32,94,,1.00E-57,Q9R0H0,Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase),GO:0003995; GO:0003997; GO:0006635; GO:0033540; GO:0050660; GO:0005739; GO:0005778; GO:0007283,acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA oxidase; flavin adenine dinucleotide binding; mitochondrion; peroxisomal membrane; spermatogenesis,PF01756;PF02770;PF14749;,,,,,,,,,ACOX1_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; peroxisome fission [GO:0016559]; positive regulation of cholesterol homeostasis [GO:2000189]; prostaglandin metabolic process [GO:0006693]; spermatogenesis [GO:0007283]; very long-chain fatty acid metabolic process [GO:0000038] comp135770_c1_seq2,852,41.3146,0.4139175,0,0,,5.00E-08,P08790,Acyl-coenzyme A oxidase 5 (Acyl-CoA oxidase 5) (EC 1.3.3.6) (PXP-5),Acyl-coenzyme A oxidase 5 (Acyl-CoA oxidase 5) (EC 1.3.3.6) (PXP-5),GO:0003995; GO:0003997; GO:0033540; GO:0050660; GO:0005777,acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; fatty acid beta-oxidation using acyl-CoA oxidase; flavin adenine dinucleotide binding; peroxisome,PF01756;PF00441;PF02770;PF14749;,,,,,,,,,ACOX5_CANTR,Candida tropicalis (Yeast),fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540] comp135774_c0_seq1,1943,42.8204,0.82041935,5,0,,3.00E-16,O60304,Zinc finger protein 500 (Zinc finger protein with KRAB and SCAN domains 18),Zinc finger protein 500 (Zinc finger protein with KRAB and SCAN domains 18),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZN500_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp135774_c0_seq2,1248,40.5449,0.80924515,0,0,,7.00E-61,Q02446,Transcription factor Sp4 (SPR-1),Transcription factor Sp4 (SPR-1),GO:0003677; GO:0046872; GO:0005634; GO:0006357; GO:0003700; GO:0003713; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription, DNA-dependent",,3.00E-50,CHOYP_SP3.1.1,,,,,,,SP4_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135774_c0_seq4,1943,42.8204,0.80880666,2,0,,9.00E-60,Q02446,Transcription factor Sp4 (SPR-1),Transcription factor Sp4 (SPR-1),GO:0003677; GO:0046872; GO:0005634; GO:0006357; GO:0003700; GO:0003713; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription, DNA-dependent",,4.00E-50,CHOYP_SP3.1.1,,,,,,,SP4_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135775_c0_seq1,1685,38.8131,0.5222805,322,803,,4.00E-100,Q9U4L6,Mitochondrial import receptor subunit TOM40 homolog 1 (dtom40) (Male sterile protein 15) (Translocase of outer membrane 40 kDa subunit homolog 1),Mitochondrial import receptor subunit TOM40 homolog 1 (dtom40) (Male sterile protein 15) (Translocase of outer membrane 40 kDa subunit homolog 1),GO:0071456; GO:0006811; GO:0005741; GO:0046930; GO:0015288; GO:0006626,cellular response to hypoxia; ion transport; mitochondrial outer membrane; pore complex; porin activity; protein targeting to mitochondrion,PF01459;,,,1.00E-27,ruditapes2_c698,,,,,TO401_DROME,Drosophila melanogaster (Fruit fly),cellular response to hypoxia [GO:0071456]; ion transport [GO:0006811]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] comp135776_c0_seq1,431,44.3155,0.38070264,8,55,,4.00E-09,Q8BZJ8,Uncharacterized protein C8orf34 homolog,Uncharacterized protein C8orf34 homolog,,,,,,,,,,,,CH034_MOUSE,Mus musculus (Mouse), comp135777_c0_seq1,1762,40.2951,0.23930669,1,11,,1.00E-28,Q54XP3,tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),GO:0003723; GO:0046872; GO:0006400; GO:0008251,RNA binding; metal ion binding; tRNA modification; tRNA-specific adenosine deaminase activity,PF02137;,,,,,,,,,ADAT1_DICDI,Dictyostelium discoideum (Slime mold),tRNA modification [GO:0006400]; tRNA processing [GO:0008033] comp135777_c0_seq2,1645,40,0.24396037,0,20,,2.00E-61,Q28FE8,tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),GO:0003723; GO:0046872; GO:0008033; GO:0008251,RNA binding; metal ion binding; tRNA processing; tRNA-specific adenosine deaminase activity,PF02137;,2.00E-27,CHOYP_LOC100705296.1.1,,,,,,,ADAT1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),tRNA processing [GO:0008033] comp135777_c0_seq3,912,41.4474,0.23519506,0,0,,4.00E-61,Q5ZI16,tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),GO:0003723; GO:0046872; GO:0008033; GO:0008251,RNA binding; metal ion binding; tRNA processing; tRNA-specific adenosine deaminase activity,PF02137;,1.00E-27,CHOYP_LOC100705296.1.1,,,,,,,ADAT1_CHICK,Gallus gallus (Chicken),tRNA processing [GO:0008033] comp135777_c0_seq4,1162,40.5336,0.16991137,0,0,,4.00E-63,Q28FE8,tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase),GO:0003723; GO:0046872; GO:0008033; GO:0008251,RNA binding; metal ion binding; tRNA processing; tRNA-specific adenosine deaminase activity,PF02137;,,,,,,,,,ADAT1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),tRNA processing [GO:0008033] comp135779_c0_seq2,908,40.0881,0.61187848,26,56,,1.00E-42,O82796,"Phosphoserine phosphatase, chloroplastic (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase)","Phosphoserine phosphatase, chloroplastic (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase)",GO:0006564; GO:0005509; GO:0009507; GO:0009790; GO:0000287; GO:0004647; GO:0009555; GO:0048364,L-serine biosynthetic process; calcium ion binding; chloroplast; embryo development; magnesium ion binding; phosphoserine phosphatase activity; pollen development; root development,,,,,,,,,,SERB_ARATH,Arabidopsis thaliana (Mouse-ear cress),embryo development ending in seed dormancy [GO:0009793]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; pollen development [GO:0009555]; root development [GO:0048364] comp135779_c0_seq3,592,43.9189,0.57239546,0,0,,3.00E-62,Q2KHU0,Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (L-3-phosphoserine phosphatase) (O-phosphoserine phosphohydrolase),Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (L-3-phosphoserine phosphatase) (O-phosphoserine phosphohydrolase),GO:0006564; GO:0005509; GO:0005737; GO:0000287; GO:0004647,L-serine biosynthetic process; calcium ion binding; cytoplasm; magnesium ion binding; phosphoserine phosphatase activity,,,,,,,,,,SERB_BOVIN,Bos taurus (Bovine),L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563] comp135781_c0_seq1,2419,49.6073,0.52771077,120,33,,5.00E-25,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,7.00E-29,CHOYP_LOC100367237.1.2,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp135783_c1_seq2,1371,41.3567,0.83914418,14,2,,4.00E-66,P16924,"Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)","Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)",GO:0031418; GO:0005788; GO:0005506; GO:0016702; GO:0004656,"L-ascorbic acid binding; endoplasmic reticulum lumen; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; procollagen-proline 4-dioxygenase activity",PF13640;PF08336;,,,,,,,,,P4HA1_CHICK,Gallus gallus (Chicken), comp135787_c0_seq1,1256,38.7739,0.50292277,141,93,,7.00E-43,P41732,Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231),Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231),GO:0005887; GO:0019048,integral to plasma membrane; modulation by virus of host morphology or physiology,PF00335;,2.00E-38,CHOYP_BRAFLDRAFT_265104.1.1,,,,,,,TSN7_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; viral process [GO:0016032] comp135789_c0_seq1,1258,39.6661,0.46697336,84,53,,4.00E-28,Q55A09,Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1),GO:0005524; GO:0016021; GO:0004674,ATP binding; integral to membrane; protein serine/threonine kinase activity,PF07714;,,,,,,,,,Y9963_DICDI,Dictyostelium discoideum (Slime mold), comp135789_c0_seq2,1557,42.0681,0.27610212,32,27,,5.00E-54,P42689,Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment),Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment),GO:0005524; GO:0005737; GO:0004715; GO:0018108,ATP binding; cytoplasm; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF07714;,,,,,,,,,SRK3_SPOLA,Spongilla lacustris (Freshwater sponge), comp135789_c0_seq3,1256,39.4108,0.28907962,4,0,,4.00E-39,P54758,Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2),Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2),GO:0005524; GO:0005003; GO:0005887; GO:0018108,ATP binding; ephrin receptor activity; integral to plasma membrane; peptidyl-tyrosine phosphorylation,PF14575;PF01404;PF00041;PF07714;PF00536;,,,,,,,,,EPHA6_RAT,Rattus norvegicus (Rat), comp135789_c0_seq4,554,43.6823,0.37972209,1,4,,3.00E-08,Q09YN5,Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),GO:0005524; GO:0016021; GO:0007275; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;PF01403;PF01833;,,,,,,,,,MET_RABIT,Oryctolagus cuniculus (Rabbit),branching morphogenesis of an epithelial tube [GO:0048754]; endothelial cell morphogenesis [GO:0001886]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp135789_c1_seq2,955,43.1414,0.22536564,3,0,,1.00E-14,Q24592,Tyrosine-protein kinase hopscotch (EC 2.7.10.2),Tyrosine-protein kinase hopscotch (EC 2.7.10.2),GO:0005524; GO:0007262; GO:0003383; GO:0007298; GO:0006968; GO:0001751; GO:0005737; GO:0005856; GO:0051607; GO:0035010; GO:0012505; GO:0045317; GO:0007455; GO:0042078; GO:0035172; GO:0007442; GO:0006959; GO:0007480; GO:0007476; GO:0035171; GO:0045475; GO:0007616; GO:0060031; GO:0016020; GO:0016318; GO:0007424; GO:0030713; GO:0007365; GO:0007538; GO:0004713; GO:0046425; GO:0016476; GO:0045610; GO:0035206; GO:0006355; GO:0048103; GO:0019827; GO:0006351; GO:0007260,"ATP binding; STAT protein import into nucleus; apical constriction; border follicle cell migration; cellular defense response; compound eye photoreceptor cell differentiation; cytoplasm; cytoskeleton; defense response to virus; encapsulation of foreign target; endomembrane system; equator specification; eye-antennal disc morphogenesis; germ-line stem cell division; hemocyte proliferation; hindgut morphogenesis; humoral immune response; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing morphogenesis; lamellocyte differentiation; locomotor rhythm; long-term memory; mediolateral intercalation; membrane; ommatidial rotation; open tracheal system development; ovarian follicle cell stalk formation; periodic partitioning; primary sex determination; protein tyrosine kinase activity; regulation of JAK-STAT cascade; regulation of embryonic cell shape; regulation of hemocyte differentiation; regulation of hemocyte proliferation; regulation of transcription, DNA-dependent; somatic stem cell division; stem cell maintenance; transcription, DNA-dependent; tyrosine phosphorylation of STAT protein",PF07714;,,,,,,,,,JAK_DROME,Drosophila melanogaster (Fruit fly),"apical constriction [GO:0003383]; blastoderm segmentation [GO:0007350]; border follicle cell migration [GO:0007298]; cell proliferation [GO:0008283]; cellular defense response [GO:0006968]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; defense response [GO:0006952]; defense response to virus [GO:0051607]; encapsulation of foreign target [GO:0035010]; equator specification [GO:0045317]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc morphogenesis [GO:0007455]; germ-line stem cell division [GO:0042078]; hemocyte differentiation [GO:0042386]; hemocyte proliferation [GO:0035172]; hemopoiesis [GO:0030097]; hindgut morphogenesis [GO:0007442]; humoral immune response [GO:0006959]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; immune response [GO:0006955]; innate immune response [GO:0045087]; JAK-STAT cascade [GO:0007259]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; mediolateral intercalation [GO:0060031]; nervous system development [GO:0007399]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peptidyl-tyrosine autophosphorylation [GO:0038083]; periodic partitioning [GO:0007365]; primary sex determination [GO:0007538]; protein phosphorylation [GO:0006468]; regulation of embryonic cell shape [GO:0016476]; regulation of hemocyte differentiation [GO:0045610]; regulation of hemocyte proliferation [GO:0035206]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription, DNA-templated [GO:0006355]; sex determination [GO:0007530]; somatic stem cell division [GO:0048103]; STAT protein import into nucleus [GO:0007262]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tyrosine phosphorylation of STAT protein [GO:0007260]" comp135789_c1_seq5,2755,40.3267,0.38512891,0,0,,2.00E-22,Q63272,Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3),Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3),GO:0005524; GO:0030183; GO:0043029; GO:0019221; GO:0005737; GO:0005856; GO:0007204; GO:0012505; GO:0007167; GO:0045087; GO:0016020; GO:0045221; GO:0045626; GO:0002731; GO:0032693; GO:0032695; GO:0070244; GO:0004715; GO:0042104; GO:0051928; GO:0050778; GO:0046777; GO:0004713; GO:0008134; GO:0042506,ATP binding; B cell differentiation; T cell homeostasis; cytokine-mediated signaling pathway; cytoplasm; cytoskeleton; elevation of cytosolic calcium ion concentration; endomembrane system; enzyme linked receptor protein signaling pathway; innate immune response; membrane; negative regulation of FasL biosynthetic process; negative regulation of T-helper 1 cell differentiation; negative regulation of dendritic cell cytokine production; negative regulation of interleukin-10 production; negative regulation of interleukin-12 production; negative regulation of thymocyte apoptotic process; non-membrane spanning protein tyrosine kinase activity; positive regulation of activated T cell proliferation; positive regulation of calcium ion transport; positive regulation of immune response; protein autophosphorylation; protein tyrosine kinase activity; transcription factor binding; tyrosine phosphorylation of Stat5 protein,PF07714;,,,,,,,,,JAK3_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; cell migration [GO:0016477]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of dendritic cell cytokine production [GO:0002731]; negative regulation of FasL biosynthetic process [GO:0045221]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of T cell activation [GO:0050868]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; negative regulation of thymocyte apoptotic process [GO:0070244]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of immune response [GO:0050778]; positive regulation of T cell proliferation [GO:0042102]; protein autophosphorylation [GO:0046777]; regulation of T cell apoptotic process [GO:0070232]; T cell homeostasis [GO:0043029]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tyrosine phosphorylation of Stat5 protein [GO:0042506] comp135791_c0_seq2,1256,43.551,0.90933262,0,0,,2.00E-07,Q8N7X2,Uncharacterized protein C9orf173,Uncharacterized protein C9orf173,,,,2.00E-13,CHOYP_LOC100378134.1.1,,,,,,,CI173_HUMAN,Homo sapiens (Human), comp135791_c4_seq3,1169,33.3618,1.23128823,173,20,,1.00E-34,P52899,"Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)","Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)",GO:0006096; GO:0005759; GO:0005739; GO:0004739,glycolysis; mitochondrial matrix; mitochondrion; pyruvate dehydrogenase (acetyl-transferring) activity,PF00676;,,,,,,,,,ODPA_CAEEL,Caenorhabditis elegans,acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] comp135792_c0_seq1,1663,36.6206,0.47459429,167,508,,2.00E-68,P51947,Cyclin-H (MO15-associated protein) (p36),Cyclin-H (MO15-associated protein) (p36),GO:0070985; GO:0007049; GO:0016538; GO:0000079; GO:0006355; GO:0006351,"TFIIK complex; cell cycle; cyclin-dependent protein serine/threonine kinase regulator activity; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16899;PF00134;,1.00E-43,CHOYP_AGAP_AGAP008417.1.1,,,,,,,CCNH_XENLA,Xenopus laevis (African clawed frog),"cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135793_c0_seq1,1288,37.8106,0.49977119,153,1363,,8.00E-77,Q8C3I8,Protein FAM203A (Brain protein 16),Protein HGH1 homolog,,,PF04063;PF04064;,3.00E-11,CHOYP_RFC2.1.2,,,,,,,F203A_MOUSE,Mus musculus (Mouse), comp135795_c0_seq5,1548,34.5607,0.33053104,1,14,,2.00E-08,Q57951,Universal stress protein MJ0531 (USP MJ0531),Universal stress protein MJ0531 (USP MJ0531),GO:0006950,response to stress,PF00582;,,,,,,,,,Y531_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),response to stress [GO:0006950] comp135797_c0_seq1,1513,37.4091,1.00196085,4,997,female>male,5.00E-62,Q15125,"3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)","3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)",GO:0000247; GO:0047750; GO:0006695; GO:0015238; GO:0005789; GO:0030097; GO:0005887; GO:0001501; GO:0004769; GO:0004888,C-8 sterol isomerase activity; cholestenol delta-isomerase activity; cholesterol biosynthetic process; drug transmembrane transporter activity; endoplasmic reticulum membrane; hemopoiesis; integral to plasma membrane; skeletal system development; steroid delta-isomerase activity; transmembrane signaling receptor activity,PF05241;,,,,,,,,,EBP_HUMAN,Homo sapiens (Human),cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; cholesterol metabolic process [GO:0008203]; hemopoiesis [GO:0030097]; skeletal system development [GO:0001501] comp135800_c0_seq2,2443,46.5002,0.45882504,0,0,,1.00E-15,Q51567,Succinyl-CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha),Succinate--CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha),GO:0005524; GO:0003878; GO:0048037; GO:0006091; GO:0004775; GO:0006099,ATP binding; ATP citrate synthase activity; cofactor binding; generation of precursor metabolites and energy; succinate-CoA ligase (ADP-forming) activity; tricarboxylic acid cycle,PF02629;PF00549;,0,CHOYP_ACLY.1.1,,,,,,,SUCD_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),nucleoside triphosphate biosynthetic process [GO:0009142]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] comp135800_c0_seq3,2456,46.5798,0.45493268,3,0,,0,Q8X097,Probable ATP-citrate synthase subunit 1 (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase 1) (Citrate cleavage enzyme subunit 1),Probable ATP-citrate synthase subunit 1 (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase 1) (Citrate cleavage enzyme subunit 1),GO:0005524; GO:0003878; GO:0044262; GO:0048037; GO:0005737; GO:0006629; GO:0046872; GO:0004775,ATP binding; ATP citrate synthase activity; cellular carbohydrate metabolic process; cofactor binding; cytoplasm; lipid metabolic process; metal ion binding; succinate-CoA ligase (ADP-forming) activity,PF00285;PF02629;PF00549;,,,,,,,,,ACL1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),lipid metabolic process [GO:0006629] comp135800_c0_seq4,2660,46.9925,0.46768197,0,0,,0,Q91V92,ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme),ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme),GO:0005524; GO:0003878; GO:0006085; GO:0044262; GO:0048037; GO:0008610; GO:0046872; GO:0005739; GO:0004775,ATP binding; ATP citrate synthase activity; acetyl-CoA biosynthetic process; cellular carbohydrate metabolic process; cofactor binding; lipid biosynthetic process; metal ion binding; mitochondrion; succinate-CoA ligase (ADP-forming) activity,PF16114;PF00285;PF02629;PF00549;,,,,,,,,,ACLY_MOUSE,Mus musculus (Mouse),acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107] comp135800_c0_seq5,2647,46.8455,0.47285721,0,0,,0,Q91V92,ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme),ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme),GO:0005524; GO:0003878; GO:0006085; GO:0044262; GO:0048037; GO:0008610; GO:0046872; GO:0005739; GO:0004775,ATP binding; ATP citrate synthase activity; acetyl-CoA biosynthetic process; cellular carbohydrate metabolic process; cofactor binding; lipid biosynthetic process; metal ion binding; mitochondrion; succinate-CoA ligase (ADP-forming) activity,PF16114;PF00285;PF02629;PF00549;,0,CHOYP_ACLY.1.1,,,,,,,ACLY_MOUSE,Mus musculus (Mouse),acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107] comp135800_c0_seq7,1185,42.616,0.45651997,0,0,,3.00E-07,P63777,Putative citrate synthase 2 (EC 2.3.3.1),,GO:0044262; GO:0004108; GO:0005829; GO:0006099,cellular carbohydrate metabolic process; citrate (Si)-synthase activity; cytosol; tricarboxylic acid cycle,,,,,,,,,,CISY2_MYCTU,, comp135800_c0_seq8,1387,48.1615,0.49869335,0,0,,4.00E-53,O13907,Probable ATP-citrate synthase subunit 2 (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase 2) (Citrate cleavage enzyme subunit 2),Probable ATP-citrate synthase subunit 2 (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase 2) (Citrate cleavage enzyme subunit 2),GO:0005524; GO:0003878; GO:0006085; GO:0006101; GO:0005829; GO:0006633; GO:0005634; GO:0006099,ATP binding; ATP citrate synthase activity; acetyl-CoA biosynthetic process; citrate metabolic process; cytosol; fatty acid biosynthetic process; nucleus; tricarboxylic acid cycle,PF08442;PF16114;,,,,,,,,,ACL2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; fatty acid biosynthetic process [GO:0006633] comp135800_c0_seq9,1172,42.2355,0.46979542,0,0,,1.00E-07,P80148,Citrate synthase (EC 2.3.3.1),Citrate synthase (EC 2.3.3.16),GO:0044262; GO:0004108; GO:0005737; GO:0006099,cellular carbohydrate metabolic process; citrate (Si)-synthase activity; cytoplasm; tricarboxylic acid cycle,PF00285;,,,,,,,,,CISY_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2),tricarboxylic acid cycle [GO:0006099] comp135801_c1_seq1,1692,36.4657,0.64223415,5411,750,,1.00E-42,A2BFC9,Uncharacterized protein FLJ46082 homolog,Uncharacterized protein C9orf171 homolog,,,PF14825;,4.00E-37,CHOYP_BRAFLDRAFT_263840.1.1,,,,,,,YI011_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp135802_c1_seq1,1107,47.2448,0.48673384,0,0,,5.00E-06,P54792,Putative segment polarity protein dishevelled homolog DVL1P1 (DSH homolog 1-like) (Segment polarity protein dishevelled homolog DVL-1-like) (Dishevelled-1-like),Putative segment polarity protein dishevelled homolog DVL1P1 (DSH homolog 1-like) (Segment polarity protein dishevelled homolog DVL-1-like) (Dishevelled-1-like),GO:0016055; GO:0005737; GO:0007507; GO:0035556; GO:0004871; GO:0007165,Wnt receptor signaling pathway; cytoplasm; heart development; intracellular signal transduction; signal transducer activity; signal transduction,PF00610;PF02377;PF00778;PF12316;PF00595;,,,,,,,,,DVL1L_HUMAN,Homo sapiens (Human),canonical Wnt signaling pathway [GO:0060070]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; planar cell polarity pathway involved in neural tube closure [GO:0090179] comp135802_c1_seq2,2681,47.5569,0.56025632,92,147,,3.00E-122,O55164,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0007155; GO:0031410; GO:0030425; GO:0012505; GO:0035556; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; cell adhesion; cytoplasmic vesicle; dendrite; endomembrane system; intracellular signal transduction; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,1.00E-63,CHOYP_MPDZ.3.3,,,,,,,MPDZ_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; myelination [GO:0042552] comp135805_c0_seq1,1332,46.9219,0.43698674,0,35,,2.00E-19,Q80SY4,E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1),E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1),GO:0007219; GO:0001568; GO:0005813; GO:0031410; GO:0001947; GO:0001701; GO:0045665; GO:0001841; GO:0031965; GO:0005886; GO:0045807; GO:0001756; GO:0004842; GO:0008270,Notch signaling pathway; blood vessel development; centrosome; cytoplasmic vesicle; heart looping; in utero embryonic development; negative regulation of neuron differentiation; neural tube formation; nuclear membrane; plasma membrane; positive regulation of endocytosis; somitogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,0,CHOYP_TNKS1.2.5,,,,,,,MIB1_MOUSE,Mus musculus (Mouse),blood vessel development [GO:0001568]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756] comp135805_c0_seq2,958,48.8518,0.40448596,0,0,,8.00E-23,Q9EQG6,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0030165; GO:0016482; GO:0005829; GO:0016021; GO:0005770; GO:0038180; GO:0010976; GO:0043234; GO:0019901; GO:0019887,PDZ domain binding; cytoplasmic transport; cytosol; integral to membrane; late endosome; nerve growth factor signaling pathway; positive regulation of neuron projection development; protein complex; protein kinase binding; protein kinase regulator activity,PF12796;PF07693;,,,,,,,,,KDIS_RAT,Rattus norvegicus (Rat),activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976] comp135805_c0_seq3,1391,47.7354,0.52006588,29,0,,0,Q6PFX9,Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),GO:0005794; GO:0000139; GO:0003950; GO:0016055; GO:0051301; GO:0000775; GO:0051028; GO:0007067; GO:0043392; GO:0000784; GO:0005643; GO:0018105; GO:0018107; GO:0090263; GO:0032212; GO:0045944; GO:0070213; GO:0070198; GO:0070212; GO:0000209; GO:0015031; GO:0000922; GO:0008270,"Golgi apparatus; Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; cell division; chromosome, centromeric region; mRNA transport; mitosis; negative regulation of DNA binding; nuclear chromosome, telomeric region; nuclear pore; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of telomere maintenance via telomerase; positive regulation of transcription from RNA polymerase II promoter; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein poly-ADP-ribosylation; protein polyubiquitination; protein transport; spindle pole; zinc ion binding",PF00023;PF12796;PF13606;PF00644;PF07647;,0,CHOYP_TNKS1.1.5,,,,,,,TNKS1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]" comp135805_c0_seq4,1543,47.3752,0.53701122,168,207,,0,Q6PFX9,Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),GO:0005794; GO:0000139; GO:0003950; GO:0016055; GO:0051301; GO:0000775; GO:0051028; GO:0007067; GO:0043392; GO:0000784; GO:0005643; GO:0018105; GO:0018107; GO:0090263; GO:0032212; GO:0045944; GO:0070213; GO:0070198; GO:0070212; GO:0000209; GO:0015031; GO:0000922; GO:0008270,"Golgi apparatus; Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; cell division; chromosome, centromeric region; mRNA transport; mitosis; negative regulation of DNA binding; nuclear chromosome, telomeric region; nuclear pore; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of telomere maintenance via telomerase; positive regulation of transcription from RNA polymerase II promoter; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein poly-ADP-ribosylation; protein polyubiquitination; protein transport; spindle pole; zinc ion binding",PF00023;PF12796;PF13606;PF00644;PF07647;,0,CHOYP_TNKS1.2.5,,,,,,,TNKS1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]" comp135805_c1_seq2,1060,40,0.68062744,43,29,,2.00E-06,Q9NR21,Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11),Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11),GO:0003950,NAD+ ADP-ribosyltransferase activity,PF00644;PF02825;,,,,,,,,,PAR11_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] comp135806_c0_seq1,1210,45.0413,0.47648735,71,181,,1.00E-102,Q91YN0,Uncharacterized protein C12orf4 homolog,Protein C12orf4 homolog,,,PF10154;,2.00E-95,CHOYP_BRAFLDRAFT_283171.1.1,,,,,,,CL004_MOUSE,Mus musculus (Mouse),regulation of mast cell degranulation [GO:0043304] comp135811_c0_seq1,1518,49.4071,0.3723873,19,144,,4.00E-48,Q8IWX8,Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6),Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6),GO:0003723; GO:0006396; GO:0008285; GO:0007399; GO:0048471; GO:0051533; GO:0051209; GO:0033017,RNA binding; RNA processing; negative regulation of cell proliferation; nervous system development; perinuclear region of cytoplasm; positive regulation of NFAT protein import into nucleus; release of sequestered calcium ion into cytosol; sarcoplasmic reticulum membrane,PF04818;PF01585;PF01805;,,,,,,,,,CHERP_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; positive regulation of NFAT protein import into nucleus [GO:0051533]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] comp135811_c0_seq3,1136,36.7958,0.9913961,0,0,,9.00E-07,O13900,Pre-mRNA-splicing factor sap114 (Spliceosome-associated protein 145),Pre-mRNA-splicing factor sap114 (Spliceosome-associated protein 145),GO:0003723; GO:0005686; GO:0045292; GO:0005681,"RNA binding; U2 snRNP; mRNA cis splicing, via spliceosome; spliceosomal complex",PF12230;PF01805;,4.00E-28,CHOYP_CHERP.1.1,,,,,,,SA114_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA 3'-splice site recognition [GO:0000389]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp135811_c0_seq4,988,40.8907,1.06688351,10,149,,,,,,,,,,,5.00E-30,ruditapes2_c444,,,,,,, comp135812_c0_seq4,2387,44.0721,0.64260089,109,861,,0,Q5I598,Methylenetetrahydrofolate reductase (EC 1.5.1.20),Methylenetetrahydrofolate reductase (EC 1.5.1.20),GO:0006555; GO:0004489; GO:0035999,methionine metabolic process; methylenetetrahydrofolate reductase (NAD(P)H) activity; tetrahydrofolate interconversion,PF02219;,0,CHOYP_MTHR.1.1,,,,,,,MTHR_BOVIN,Bos taurus (Bovine),methionine metabolic process [GO:0006555]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999] comp135813_c0_seq1,544,42.8309,0.85017372,18,826,,4.00E-35,Q8BG58,Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),GO:0031418; GO:0005509; GO:0005789; GO:0016021; GO:0005506; GO:0016706,"L-ascorbic acid binding; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13640;PF13499;,,,,,,,,,P4HTM_MOUSE,Mus musculus (Mouse),regulation of erythrocyte differentiation [GO:0045646] comp135817_c0_seq1,2244,43.4938,0.55792421,0,0,,0,P28173,Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT),Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT),GO:0006189; GO:0051539; GO:0004044; GO:0005829; GO:0006541; GO:0046872; GO:0009116; GO:0009113; GO:0006144,"'de novo' IMP biosynthetic process; 4 iron, 4 sulfur cluster binding; amidophosphoribosyltransferase activity; cytosol; glutamine metabolic process; metal ion binding; nucleoside metabolic process; purine nucleobase biosynthetic process; purine nucleobase metabolic process",PF00156;,,,,,,,,,PUR1_CHICK,Gallus gallus (Chicken),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113] comp135817_c0_seq2,2130,43.5681,0.55333676,0,0,,4.00E-06,Q58815,Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase) [Cleaved into: Mja gf6p intein],Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase) [Cleaved into: Mja gf6p intein],GO:0030246; GO:0016051; GO:0005737; GO:0004519; GO:0006541; GO:0004360; GO:0016539; GO:0043565,carbohydrate binding; carbohydrate biosynthetic process; cytoplasm; endonuclease activity; glutamine metabolic process; glutamine-fructose-6-phosphate transaminase (isomerizing) activity; intein-mediated protein splicing; sequence-specific DNA binding,PF13537;PF01381;PF14528;PF01380;,,,,,,,,,GLMS_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),carbohydrate derivative biosynthetic process [GO:1901137]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; intein-mediated protein splicing [GO:0016539]; UDP-N-acetylglucosamine metabolic process [GO:0006047] comp135817_c0_seq5,2051,43.9785,0.52475042,0,0,,4.00E-121,Q55038,Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase),Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase),GO:0006189; GO:0051539; GO:0004044; GO:0006541; GO:0046872; GO:0009116; GO:0009113,"'de novo' IMP biosynthetic process; 4 iron, 4 sulfur cluster binding; amidophosphoribosyltransferase activity; glutamine metabolic process; metal ion binding; nucleoside metabolic process; purine nucleobase biosynthetic process",PF00156;,,,,,,,,,PUR1_SYNE7,Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113] comp135817_c0_seq6,1937,44.0888,0.51818196,0,0,,0,P28173,Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT),Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT),GO:0006189; GO:0051539; GO:0004044; GO:0005829; GO:0006541; GO:0046872; GO:0009116; GO:0009113; GO:0006144,"'de novo' IMP biosynthetic process; 4 iron, 4 sulfur cluster binding; amidophosphoribosyltransferase activity; cytosol; glutamine metabolic process; metal ion binding; nucleoside metabolic process; purine nucleobase biosynthetic process; purine nucleobase metabolic process",PF00156;,4.00E-132,CHOYP_PUR1.1.1,,,,,,,PUR1_CHICK,Gallus gallus (Chicken),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113] comp135821_c0_seq1,823,43.9854,0.60839961,1535,4491,,2.00E-22,Q9VLJ9,"39S ribosomal protein L51, mitochondrial (L51mt) (MRP-L51)","39S ribosomal protein L51, mitochondrial (L51mt) (MRP-L51)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF10244;,,,,,,,,,RM51_DROME,Drosophila melanogaster (Fruit fly),mitochondrial translation [GO:0032543]; translation [GO:0006412] comp135825_c0_seq1,3703,37.6452,0.68881539,0,0,,6.00E-73,Q96RU3,Formin-binding protein 1 (Formin-binding protein 17) (hFBP17),Formin-binding protein 1 (Formin-binding protein 17) (hFBP17),GO:0005938; GO:0005905; GO:0016023; GO:0005856; GO:0006897; GO:0008289; GO:0005764; GO:0005886,cell cortex; coated pit; cytoplasmic membrane-bounded vesicle; cytoskeleton; endocytosis; lipid binding; lysosome; plasma membrane,PF00611;PF14604;,3.00E-54,CHOYP_LOC100122293.1.2,,,,,,,FNBP1_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; vesicle-mediated transport [GO:0016192] comp135825_c0_seq10,3715,37.6851,0.69274512,0,0,,6.00E-73,Q96RU3,Formin-binding protein 1 (Formin-binding protein 17) (hFBP17),Formin-binding protein 1 (Formin-binding protein 17) (hFBP17),GO:0005938; GO:0005905; GO:0016023; GO:0005856; GO:0006897; GO:0008289; GO:0005764; GO:0005886,cell cortex; coated pit; cytoplasmic membrane-bounded vesicle; cytoskeleton; endocytosis; lipid binding; lysosome; plasma membrane,PF00611;PF14604;,4.00E-53,CHOYP_LOC100122293.2.2,,,,,,,FNBP1_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; vesicle-mediated transport [GO:0016192] comp135825_c0_seq11,3727,37.7515,0.69574781,0,0,,3.00E-70,Q6GNV5,Formin-binding protein 1 homolog,Formin-binding protein 1 homolog,GO:0005938; GO:0005905; GO:0016023; GO:0005856; GO:0006897; GO:0008289; GO:0005764; GO:0005886,cell cortex; coated pit; cytoplasmic membrane-bounded vesicle; cytoskeleton; endocytosis; lipid binding; lysosome; plasma membrane,PF00611;PF00018;,,,,,,,,,FNBP1_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897] comp135825_c0_seq13,1339,36.6692,0.73991073,0,0,,,,,,,,,3.00E-49,CHOYP_LOC100122293.2.2,,,,,,,,, comp135825_c0_seq15,1251,36.7706,0.71598818,0,0,,2.00E-77,Q96RU3,Formin-binding protein 1 (Formin-binding protein 17) (hFBP17),Formin-binding protein 1 (Formin-binding protein 17) (hFBP17),GO:0005938; GO:0005905; GO:0016023; GO:0005856; GO:0006897; GO:0008289; GO:0005764; GO:0005886,cell cortex; coated pit; cytoplasmic membrane-bounded vesicle; cytoskeleton; endocytosis; lipid binding; lysosome; plasma membrane,PF00611;PF14604;,7.00E-51,CHOYP_LOC100122293.1.2,,,,,,,FNBP1_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; vesicle-mediated transport [GO:0016192] comp135825_c0_seq18,2719,38.8378,0.7143275,0,6,,8.00E-40,Q6DCZ7,Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1),Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1),GO:0006914; GO:0005938; GO:0016023; GO:0005856; GO:0006897; GO:0008289; GO:0005886,autophagy; cell cortex; cytoplasmic membrane-bounded vesicle; cytoskeleton; endocytosis; lipid binding; plasma membrane,PF00611;PF00018;,,,,,,,,,FBP1L_XENLA,Xenopus laevis (African clawed frog),autophagy [GO:0006914]; endocytosis [GO:0006897] comp135825_c0_seq5,1351,36.7876,0.75054739,0,0,,4.00E-08,Q55CK2,Mental retardation GTPase activating protein homolog 2 (GTPase activating factor for raC protein CC) (Rho GTPase-activating protein gacCC),Mental retardation GTPase activating protein homolog 2 (GTPase activating factor for raC protein CC) (Rho GTPase-activating protein gacCC),GO:0005096; GO:0000331; GO:0033298; GO:0006887; GO:0051490; GO:0042331; GO:0043547; GO:0051270; GO:0007165; GO:0030587,GTPase activator activity; contractile vacuole; contractile vacuole organization; exocytosis; negative regulation of filopodium assembly; phototaxis; positive regulation of GTPase activity; regulation of cellular component movement; signal transduction; sorocarp development,PF00611;PF00620;,2.00E-52,CHOYP_LOC100122293.1.2,7.00E-43,ruditapes_c20217,,,,,MGP2_DICDI,Dictyostelium discoideum (Slime mold),contractile vacuole organization [GO:0033298]; exocytosis [GO:0006887]; negative regulation of filopodium assembly [GO:0051490]; phototaxis [GO:0042331]; regulation of cellular component movement [GO:0051270]; signal transduction [GO:0007165]; sorocarp development [GO:0030587] comp135825_c0_seq8,2697,38.7468,0.70316931,5,7,,,,,,,,,4.00E-20,CHOYP_LOC100122293.2.2,,,,,,,,, comp135828_c0_seq1,2087,38.3325,0.52698622,164,394,,2.00E-15,Q5ZLY0,Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein),Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein),GO:0003723; GO:0005737; GO:0005634; GO:0015031,RNA binding; cytoplasm; nucleus; protein transport,PF10258;,,,,,,,,,PHAX_CHICK,Gallus gallus (Chicken),protein transport [GO:0015031]; snRNA export from nucleus [GO:0006408] comp135829_c2_seq1,1128,42.3759,1.04762237,0,0,,2.00E-49,Q9Z2J0,Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3),Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3),GO:0008520; GO:0016324; GO:0009925; GO:0007420; GO:0005903; GO:0005737; GO:0033300; GO:0016021; GO:0043229; GO:0030324; GO:0009636; GO:0070890; GO:0070904,L-ascorbate:sodium symporter activity; apical plasma membrane; basal plasma membrane; brain development; brush border; cytoplasm; dehydroascorbic acid transporter activity; integral to membrane; intracellular organelle; lung development; response to toxic substance; sodium-dependent L-ascorbate transmembrane transporter activity; transepithelial L-ascorbic acid transport,PF00860;,,,,,,,,,S23A1_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; lung development [GO:0030324]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904] comp135829_c2_seq5,602,44.8505,1.06022271,0,0,,5.00E-11,Q3E956,Putative nucleobase-ascorbate transporter 9 (AtNAT9),Putative nucleobase-ascorbate transporter 9 (AtNAT9),GO:0016021; GO:0055085; GO:0005215,integral to membrane; transmembrane transport; transporter activity,PF00860;,4.00E-19,CHOYP_NEMVEDRAFT_V1G82490.1.1,,,,,,,NAT9_ARATH,Arabidopsis thaliana (Mouse-ear cress),transmembrane transport [GO:0055085] comp135829_c2_seq6,345,43.1884,0.99856539,9,2,,,,,,,,,1.00E-10,CHOYP_S23A2.3.3,,,,,,,,, comp135829_c3_seq1,563,48.8455,0.89694939,13,4,,,,,,,,,8.00E-15,CHOYP_S23A2.2.3,,,,,,,,, comp135832_c2_seq10,1310,44.3511,0.85462892,0,0,,1.00E-23,Q08CS6,DBH-like monooxygenase protein 2 homolog (EC 1.14.17.-),DBH-like monooxygenase protein 2 homolog (EC 1.14.17.-),GO:0006584; GO:0005507; GO:0004500; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp135832_c2_seq13,1628,43.7961,0.87208347,0,0,,8.00E-30,Q98ST7,DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_CHICK,Gallus gallus (Chicken), comp135832_c2_seq7,1409,45.4933,0.87855643,0,0,,3.00E-30,Q98ST7,DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_CHICK,Gallus gallus (Chicken), comp135835_c1_seq2,826,37.2881,0.35205024,98,96,,2.00E-16,P0C7P0,"CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2)","CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2)",GO:0051537; GO:0046872; GO:0005739,"2 iron, 2 sulfur cluster binding; metal ion binding; mitochondrion",PF09360;,6.00E-12,CHOYP_AGAP_AGAP004885.1.1,,,,,,,CISD3_HUMAN,Homo sapiens (Human), comp135837_c1_seq1,1371,40.4814,1.0083739,2,4056,female>male,8.00E-13,P42519,Protein Star,Protein Star,GO:0005794; GO:0000139; GO:0048149; GO:0046845; GO:0046667; GO:0035225; GO:0005789; GO:0038004; GO:0007173; GO:0061331; GO:0007476; GO:0016021; GO:0007498; GO:0016318; GO:0048477; GO:0097038; GO:0007422; GO:0042461; GO:0005886; GO:0000042; GO:0048865; GO:0007421; GO:0007601,"Golgi apparatus; Golgi membrane; behavioral response to ethanol; branched duct epithelial cell fate determination, open tracheal system; compound eye retinal cell programmed cell death; determination of genital disc primordium; endoplasmic reticulum membrane; epidermal growth factor receptor ligand maturation; epidermal growth factor receptor signaling pathway; epithelial cell proliferation involved in Malpighian tubule morphogenesis; imaginal disc-derived wing morphogenesis; integral to membrane; mesoderm development; ommatidial rotation; oogenesis; perinuclear endoplasmic reticulum; peripheral nervous system development; photoreceptor cell development; plasma membrane; protein targeting to Golgi; stem cell fate commitment; stomatogastric nervous system development; visual perception",,,,,,,,,,STAR_DROME,Drosophila melanogaster (Fruit fly),"behavioral response to ethanol [GO:0048149]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; compound eye photoreceptor development [GO:0042051]; compound eye retinal cell programmed cell death [GO:0046667]; determination of genital disc primordium [GO:0035225]; epidermal growth factor receptor ligand maturation [GO:0038004]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; imaginal disc-derived wing morphogenesis [GO:0007476]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; protein targeting to Golgi [GO:0000042]; R7 cell development [GO:0045467]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; stem cell fate commitment [GO:0048865]; stomatogastric nervous system development [GO:0007421]; visual perception [GO:0007601]" comp135837_c3_seq5,436,39.9083,0.53781221,205,16,,,,,,,,,,,4.00E-15,ruditapes_c23225,,,,,,, comp135837_c3_seq6,738,29.8103,0.42766282,4,54,,,,,,,,,,,1.00E-11,ruditapes_c23801,,,,,,, comp135839_c1_seq2,835,40.5988,1.13705959,22,103,,1.00E-36,Q5EB73,Transmembrane protein 246,Transmembrane protein 246,GO:0016021,integral to membrane,,,,,,,,,,TM246_RAT,Rattus norvegicus (Rat), comp135842_c0_seq1,1604,39.0898,0.80299194,1644,42,,7.00E-14,Q96M20,Cyclic nucleotide-binding domain-containing protein 2,Cyclic nucleotide-binding domain-containing protein 2,,,PF00027;,3.00E-57,CHOYP_LOC100377915.1.1,,,,,,,CT152_HUMAN,Homo sapiens (Human),spermatogenesis [GO:0007283] comp135845_c0_seq3,1387,42.5379,0.85290269,5,0,,8.00E-41,Q5T197,DC-STAMP domain-containing protein 1,DC-STAMP domain-containing protein 1,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF07782;,,,,,,,,,DCST1_HUMAN,Homo sapiens (Human), comp135845_c0_seq6,1080,41.2037,0.99784701,362,0,,1.00E-53,Q5T197,DC-STAMP domain-containing protein 1,DC-STAMP domain-containing protein 1,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF07782;,,,,,,,,,DCST1_HUMAN,Homo sapiens (Human), comp135847_c0_seq1,1667,43.1914,0.51521254,0,0,,5.00E-07,Q9Z2W1,Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1),Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1),GO:0005524; GO:0005794; GO:0051645; GO:0007163; GO:0046872; GO:0050772; GO:0006468; GO:0004674,ATP binding; Golgi apparatus; Golgi localization; establishment or maintenance of cell polarity; metal ion binding; positive regulation of axonogenesis; protein phosphorylation; protein serine/threonine kinase activity,PF00069;,,,,,,,,,STK25_MOUSE,Mus musculus (Mouse),establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542] comp135847_c0_seq6,1286,39.5023,0.40669314,2,22,,6.00E-08,Q9Z2W1,Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1),Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1),GO:0005524; GO:0005794; GO:0051645; GO:0007163; GO:0046872; GO:0050772; GO:0006468; GO:0004674,ATP binding; Golgi apparatus; Golgi localization; establishment or maintenance of cell polarity; metal ion binding; positive regulation of axonogenesis; protein phosphorylation; protein serine/threonine kinase activity,PF00069;,,,3.00E-59,ruditapes2_c426,,,,,STK25_MOUSE,Mus musculus (Mouse),establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542] comp135847_c2_seq1,1092,39.652,0.68652862,68,102,,4.00E-148,Q9P289,Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 4) (MST-4) (Mst3 and SOK1-related kinase) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK),Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK),GO:0005524; GO:0000139; GO:0006921; GO:0005829; GO:0000287; GO:0004672; GO:0004674; GO:0042981,ATP binding; Golgi membrane; cellular component disassembly involved in execution phase of apoptosis; cytosol; magnesium ion binding; protein kinase activity; protein serine/threonine kinase activity; regulation of apoptotic process,PF00069;,1.00E-167,CHOYP_LOC100121999.4.4,,,,,,,MST4_HUMAN,Homo sapiens (Human),cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; microvillus assembly [GO:0030033]; mitotic cell cycle [GO:0000278]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; response to hydrogen peroxide [GO:0042542] comp135849_c0_seq1,2178,35.3535,0.48022049,485,1963,,6.00E-121,Q9CR16,Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Rotamase D),Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Rotamase D),GO:0005528; GO:0030544; GO:0051879; GO:0006915; GO:0071492; GO:0061077; GO:0005737; GO:0030331; GO:0045111; GO:0034389; GO:0000122; GO:0005730; GO:0005654; GO:0042277; GO:0003755; GO:0043065; GO:0050714; GO:0045070; GO:0006461; GO:0015031; GO:0008134,FK506 binding; Hsp70 protein binding; Hsp90 protein binding; apoptotic process; cellular response to UV-A; chaperone-mediated protein folding; cytoplasm; estrogen receptor binding; intermediate filament cytoskeleton; lipid particle organization; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; peptide binding; peptidyl-prolyl cis-trans isomerase activity; positive regulation of apoptotic process; positive regulation of protein secretion; positive regulation of viral genome replication; protein complex assembly; protein transport; transcription factor binding,PF00160;PF13176;,4.00E-63,CHOYP_PPID.1.1,3.00E-31,ruditapes_c5351,,,,,PPID_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cellular response to UV-A [GO:0071492]; chaperone-mediated protein folding [GO:0061077]; lipid particle organization [GO:0034389]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981] comp135851_c1_seq2,1435,41.2544,1.07124874,3,0,,3.00E-08,O88854,Galanin receptor type 2 (GAL2-R) (GALR-2),Galanin receptor type 2 (GAL2-R) (GALR-2),GO:0007204; GO:0004966; GO:0016021; GO:0007194; GO:0031175; GO:0005886,elevation of cytosolic calcium ion concentration; galanin receptor activity; integral to membrane; negative regulation of adenylate cyclase activity; neuron projection development; plasma membrane,PF00001;,,,,,,,,,GALR2_MOUSE,Mus musculus (Mouse),adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; inositol phosphate metabolic process [GO:0043647]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp135852_c0_seq1,1415,39.4346,0.50813423,26,28,,2.00E-07,P70371,Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1),Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1),GO:0008301; GO:0000086; GO:0001309; GO:0051301; GO:0003682; GO:0008656; GO:0005737; GO:0003691; GO:0097194; GO:0007067; GO:0007094; GO:0032211; GO:0000783; GO:0005654; GO:0031116; GO:0045840; GO:0045931; GO:0051260; GO:0005819; GO:0010521,"DNA binding, bending; G2/M transition of mitotic cell cycle; age-dependent telomere shortening; cell division; chromatin binding; cysteine-type endopeptidase activator activity involved in apoptotic process; cytoplasm; double-stranded telomeric DNA binding; execution phase of apoptosis; mitosis; mitotic spindle assembly checkpoint; negative regulation of telomere maintenance via telomerase; nuclear telomere cap complex; nucleoplasm; positive regulation of microtubule polymerization; positive regulation of mitosis; positive regulation of mitotic cell cycle; protein homooligomerization; spindle; telomerase inhibitor activity",PF00249;PF08558;,,,,,,,,,TERF1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic telomere clustering [GO:0045141]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of DNA replication [GO:0008156]; negative regulation of establishment of protein localization to telomere [GO:1904850]; negative regulation of establishment of RNA localization to telomere [GO:1904911]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of apoptotic process [GO:0043065]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of telosome assembly [GO:1904792]; protein homooligomerization [GO:0051260]; protein localization to chromosome, telomeric region [GO:0070198]; response to drug [GO:0042493]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomeric loop formation [GO:0031627]" comp135852_c0_seq2,1403,39.4155,0.47561,31,33,,3.00E-11,P54274,Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1),Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1),GO:0008301; GO:0000086; GO:0001309; GO:0051301; GO:0003682; GO:0000781; GO:0008656; GO:0005737; GO:0003691; GO:0097194; GO:0008017; GO:0007067; GO:0007094; GO:0032214; GO:0032211; GO:0000783; GO:0005654; GO:0005634; GO:0031116; GO:0045840; GO:0045931; GO:0046982; GO:0051260; GO:0042493; GO:0005819; GO:0010521; GO:0007004; GO:0010834; GO:0042162,"DNA binding, bending; G2/M transition of mitotic cell cycle; age-dependent telomere shortening; cell division; chromatin binding; chromosome, telomeric region; cysteine-type endopeptidase activator activity involved in apoptotic process; cytoplasm; double-stranded telomeric DNA binding; execution phase of apoptosis; microtubule binding; mitosis; mitotic spindle assembly checkpoint; negative regulation of telomere maintenance via semi-conservative replication; negative regulation of telomere maintenance via telomerase; nuclear telomere cap complex; nucleoplasm; nucleus; positive regulation of microtubule polymerization; positive regulation of mitosis; positive regulation of mitotic cell cycle; protein heterodimerization activity; protein homooligomerization; response to drug; spindle; telomerase inhibitor activity; telomere maintenance via telomerase; telomere maintenance via telomere shortening; telomeric DNA binding",PF00249;PF08558;,,,,,,,,,TERF1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic telomere clustering [GO:0045141]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of DNA replication [GO:0008156]; negative regulation of establishment of macromolecular complex localization to telomere [GO:1904914]; negative regulation of establishment of protein localization to telomere [GO:1904850]; negative regulation of establishment of RNA localization to telomere [GO:1904911]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via semi-conservative replication [GO:0032214]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of apoptotic process [GO:0043065]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of telosome assembly [GO:1904792]; protein homooligomerization [GO:0051260]; response to drug [GO:0042493]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomeric loop formation [GO:0031627] comp135853_c1_seq2,1707,41.8864,0.27299044,151,71,,,,,,,,,1.00E-31,CHOYP_YLPM1.1.2,,,,,,,,, comp135856_c0_seq2,2286,43.0446,0.96598607,6648,127382,,2.00E-94,P09917,Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34),Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34),GO:0004051; GO:0019369; GO:0005829; GO:0005506; GO:0019370; GO:0002540; GO:2001300; GO:0019372; GO:0005641; GO:0016363; GO:0031965,arachidonate 5-lipoxygenase activity; arachidonic acid metabolic process; cytosol; iron ion binding; leukotriene biosynthetic process; leukotriene production involved in inflammatory response; lipoxin metabolic process; lipoxygenase pathway; nuclear envelope lumen; nuclear matrix; nuclear membrane,PF00305;PF01477;,2.00E-17,CHOYP_LOC584481.2.10,,,,,,,LOX5_HUMAN,Homo sapiens (Human),acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin metabolic process [GO:2001300]; lipoxygenase pathway [GO:0019372]; positive regulation of vasoconstriction [GO:0045907]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233] comp135862_c0_seq1,994,36.9215,0.52187514,64,683,,9.00E-37,Q9Y2B0,Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4),Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4),GO:0005783; GO:0005887; GO:0010629; GO:0045716; GO:0010988,endoplasmic reticulum; integral to plasma membrane; negative regulation of gene expression; positive regulation of low-density lipoprotein particle receptor biosynthetic process; regulation of low-density lipoprotein particle clearance,PF11938;,2.00E-13,CHOYP_BRAFLDRAFT_123969.1.1,,,,,,,CNPY2_HUMAN,Homo sapiens (Human),enzyme linked receptor protein signaling pathway [GO:0007167]; negative regulation of gene expression [GO:0010629]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; regulation of low-density lipoprotein particle clearance [GO:0010988]; tissue development [GO:0009888] comp135864_c0_seq2,237,44.7257,0.61071469,0,7,,2.00E-08,Q9ES30,Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),GO:0005581; GO:0005615; GO:0042593; GO:0042802; GO:0045721; GO:0070374; GO:0070165; GO:0050715; GO:0051897; GO:0051259,collagen; extracellular space; glucose homeostasis; identical protein binding; negative regulation of gluconeogenesis; positive regulation of ERK1 and ERK2 cascade; positive regulation of adiponectin secretion; positive regulation of cytokine secretion; positive regulation of protein kinase B signaling cascade; protein oligomerization,PF00386;PF01391;,,,,,,,,,C1QT3_MOUSE,Mus musculus (Mouse),cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206] comp135864_c0_seq5,349,45.2722,0.61847897,20,89,,2.00E-08,P83425,Heavy metal-binding protein HIP,Heavy metal-binding protein HIP,GO:0005576; GO:0046872,extracellular region; metal ion binding,PF00386;,,,,,,,,,HIP_MYTED,Mytilus edulis (Blue mussel), comp135865_c0_seq1,1232,38.7175,0.93277683,677,24,,1.00E-13,Q555N7,Putative ZDHHC-type palmitoyltransferase 4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4),Putative ZDHHC-type palmitoyltransferase 4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDHC4_DICDI,Dictyostelium discoideum (Slime mold), comp13586_c0_seq1,219,44.2922,0.93618973,3,0,,4.00E-06,P03940,Steroid 21-hydroxylase (EC 1.14.99.10) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21),Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21),GO:0005789; GO:0020037; GO:0005506; GO:0004509; GO:0005496; GO:0006694,endoplasmic reticulum membrane; heme binding; iron ion binding; steroid 21-monooxygenase activity; steroid binding; steroid biosynthetic process,PF00067;,,,,,,,,,CP21A_MOUSE,Mus musculus (Mouse),steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] comp135870_c0_seq1,645,39.3798,0.52804453,24,51,,3.00E-06,Q96RG2,PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1),PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0045719; GO:0005634; GO:0035091; GO:0045727; GO:0046777; GO:0004674; GO:2000505; GO:0070092; GO:0043576; GO:0004871,ATP binding; Golgi apparatus; negative regulation of glycogen biosynthetic process; nucleus; phosphatidylinositol binding; positive regulation of translation; protein autophosphorylation; protein serine/threonine kinase activity; regulation of energy homeostasis; regulation of glucagon secretion; regulation of respiratory gaseous exchange; signal transducer activity,PF13426;PF00069;,8.00E-22,CHOYP_AAEL_AAEL008379.1.1,,,,,,,PASK_HUMAN,Homo sapiens (Human),negative regulation of glycogen biosynthetic process [GO:0045719]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of energy homeostasis [GO:2000505]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] comp135870_c1_seq1,1360,35.7353,0.60126109,63,207,,8.00E-98,P47812,Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2),Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2),GO:0005524; GO:0004707; GO:0038066; GO:0045663; GO:1901741; GO:0010831; GO:0006357; GO:0006351,"ATP binding; MAP kinase activity; p38MAPK cascade; positive regulation of myoblast differentiation; positive regulation of myoblast fusion; positive regulation of myotube differentiation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00069;,4.00E-92,CHOYP_LOC100881316.1.1,6.00E-69,ruditapes_c22270,,,,,MK14_XENLA,Xenopus laevis (African clawed frog),"intracellular signal transduction [GO:0035556]; p38MAPK cascade [GO:0038066]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135870_c1_seq2,317,41.6404,0.59509364,8,0,,8.00E-42,Q4PNJ1,Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (Fragment),Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (Fragment),GO:0005524; GO:0004707; GO:0000165; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"ATP binding; MAP kinase activity; MAPK cascade; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;,2.00E-12,CHOYP_MK01.1.1,,,,,,,HOG1_FUSCU,Fusarium culmorum,"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135871_c1_seq1,1055,38.0095,0.34381918,33,235,,7.00E-13,Q96SZ5,2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase),2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase),GO:0047800; GO:0046872; GO:0005739,cysteamine dioxygenase activity; metal ion binding; mitochondrion,PF07847;,,,,,,,,,AEDO_HUMAN,Homo sapiens (Human),oxidation-reduction process [GO:0055114]; sulfur amino acid catabolic process [GO:0000098] comp135872_c0_seq17,457,46.3895,0.53375424,34,13,,,,,,,,,9.00E-13,CHOYP_LOC100376482.4.7,,,,,,,,, comp135872_c0_seq5,742,32.2102,0.52074667,3,0,,,,,,,,,,,1.00E-12,ruditapes_c19336,,,,,,, comp135879_c0_seq1,1596,43.0451,0.51926092,0,9,,2.00E-18,Q9NYF5,Protein FAM13B (GAP-like protein N61),Protein FAM13B (GAP-like protein N61),GO:0005096; GO:0005829; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00620;,,,,,,,,,FA13B_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; xenophagy [GO:0098792] comp135879_c0_seq2,788,42.132,0.53936512,37,22,,1.00E-23,O95630,STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase),STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase),GO:0007259; GO:0032154; GO:0005737; GO:0005769; GO:0046872; GO:0008237; GO:0000281; GO:0046580; GO:0043066; GO:0014067; GO:0005634; GO:0005886; GO:0008284; GO:0016579; GO:0006508; GO:0004843,JAK-STAT cascade; cleavage furrow; cytoplasm; early endosome; metal ion binding; metallopeptidase activity; mitotic cytokinesis; negative regulation of Ras protein signal transduction; negative regulation of apoptotic process; negative regulation of phosphatidylinositol 3-kinase cascade; nucleus; plasma membrane; positive regulation of cell proliferation; protein deubiquitination; proteolysis; ubiquitin-specific protease activity,PF01398;PF08969;,,,,,,,,,STABP_HUMAN,Homo sapiens (Human),JAK-STAT cascade [GO:0007259]; mitotic cytokinesis [GO:0000281]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of cell proliferation [GO:0008284]; protein deubiquitination [GO:0016579] comp135879_c0_seq3,924,40.5844,0.54252263,2,0,,6.00E-30,O94988,Protein FAM13A,Protein FAM13A,GO:0005096; GO:0005829; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00620;,,,,,,,,,FA13A_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp135879_c0_seq4,1930,41.658,0.53826632,95,295,,4.00E-12,Q8NE31,Protein FAM13C,Protein FAM13C,,,,2.00E-41,CHOYP_FA13A.2.2,,,,,,,FA13C_HUMAN,Homo sapiens (Human), comp135879_c0_seq5,1579,43.1286,0.52204177,1,0,,7.00E-31,O94988,Protein FAM13A,Protein FAM13A,GO:0005096; GO:0005829; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00620;,3.00E-19,CHOYP_FA13A.2.2,,,,,,,FA13A_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp135880_c0_seq2,2541,38.8823,0.74132107,0,0,,8.00E-151,Q2TLZ3,Macoilin (Transmembrane protein 57),Macoilin (Transmembrane protein 57),GO:0030424; GO:0007420; GO:0016021; GO:0031965; GO:0045202,axon; brain development; integral to membrane; nuclear membrane; synapse,PF09726;,,,,,,,,,MACOI_BOVIN,Bos taurus (Bovine),brain development [GO:0007420] comp135880_c0_seq3,1192,36.745,0.80267503,0,4,,,,,,,,,2.00E-172,CHOYP_BRAFLDRAFT_89952.1.1,,,,,,,,, comp135881_c1_seq1,1526,40.5636,0.83553291,27,514,,1.00E-17,Q949V6,Probable E3 ubiquitin-protein ligase ARI1 (EC 6.3.2.-) (ARIADNE-like protein ARI1) (Protein ariadne homolog 1),Probable E3 ubiquitin-protein ligase ARI1 (EC 6.3.2.-) (ARIADNE-like protein ARI1) (Protein ariadne homolog 1),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,PF01485;,,,,,,,,,ARI1_ARATH,Arabidopsis thaliana (Mouse-ear cress),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp135885_c1_seq1,1055,40.3791,0.53630149,37,213,,7.00E-29,Q9UTA8,Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-),Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-),GO:0044262; GO:0005829; GO:0005634; GO:0046547,cellular carbohydrate metabolic process; cytosol; nucleus; trans-aconitate 3-methyltransferase activity,PF08241;,,,8.00E-16,ruditapes_c26581,,,,,YL8A_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular carbohydrate metabolic process [GO:0044262]; methylation [GO:0032259] comp135888_c1_seq5,256,36.7188,0.3496652,0,0,,,,,,,,,,,1.00E-12,ruditapes_c27988,,,,,,, comp135888_c2_seq1,489,36.6053,0.87078303,71,415,,6.00E-32,Q8MQI6,Transcription elongation factor 1 homolog,Transcription elongation factor 1 homolog,GO:0046872; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05129;,1.00E-30,CHOYP_ISCW_ISCW008316.3.3,5.00E-58,ruditapes_c21059,,,,,ELOF1_DROME,Drosophila melanogaster (Fruit fly),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135889_c0_seq3,1344,40.1042,0.92732569,27,320,,2.00E-61,Q9MYP6,17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),GO:0005813; GO:0005829; GO:0004303; GO:0006706; GO:0047045,centrosome; cytosol; estradiol 17-beta-dehydrogenase activity; steroid catabolic process; testosterone 17-beta-dehydrogenase (NADP+) activity,,,,2.00E-18,ruditapes_c2610,,,,,DHB14_BOVIN,Bos taurus (Bovine),steroid catabolic process [GO:0006706] comp135890_c0_seq2,1449,41.4079,0.89094758,46,128,,8.00E-153,Q9Y600,Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase),Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase),GO:0034641; GO:0030170; GO:0004782; GO:0000098; GO:0042412,cellular nitrogen compound metabolic process; pyridoxal phosphate binding; sulfinoalanine decarboxylase activity; sulfur amino acid catabolic process; taurine biosynthetic process,PF00282;,4.00E-30,CHOYP_CSAD.1.1,,,,,,,CSAD_HUMAN,Homo sapiens (Human),carboxylic acid metabolic process [GO:0019752]; taurine biosynthetic process [GO:0042412] comp135891_c0_seq3,864,43.0556,0.33101808,0,0,,,,,,,,,2.00E-30,CHOYP_LOC101077787.1.3,,,,,,,,, comp135891_c0_seq4,1698,38.987,0.29946113,5,56,,1.00E-95,Q68FP5,Snurportin-1 (RNA U transporter 1),Snurportin-1 (RNA U transporter 1),GO:0000339; GO:0005737; GO:0005846; GO:0005643; GO:0006606; GO:0008565; GO:0061015,RNA cap binding; cytoplasm; nuclear cap binding complex; nuclear pore; protein import into nucleus; protein transporter activity; snRNA import into nucleus,PF11538;,,,,,,,,,SPN1_RAT,Rattus norvegicus (Rat),protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015] comp135891_c0_seq5,1677,38.879,0.30505599,7,31,,2.00E-90,Q68FP5,Snurportin-1 (RNA U transporter 1),Snurportin-1 (RNA U transporter 1),GO:0000339; GO:0005737; GO:0005846; GO:0005643; GO:0006606; GO:0008565; GO:0061015,RNA cap binding; cytoplasm; nuclear cap binding complex; nuclear pore; protein import into nucleus; protein transporter activity; snRNA import into nucleus,PF11538;,,,,,,,,,SPN1_RAT,Rattus norvegicus (Rat),protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015] comp135891_c0_seq6,1685,42.3145,0.34019382,6,78,,,,,,,,,2.00E-27,CHOYP_LOC101077787.3.3,,,,,,,,, comp135892_c0_seq1,1979,38.5043,0.60984077,1663,25989,,3.00E-28,P76536,Probable deferrochelatase/peroxidase YfeX (EC 1.11.1.-),Probable deferrochelatase/peroxidase YfeX (EC 1.11.1.-),GO:0005737; GO:0020037; GO:0046872; GO:0004601,cytoplasm; heme binding; metal ion binding; peroxidase activity,PF04261;,2.00E-130,CHOYP_LOC100371249.1.1,,,,,,,YFEX_ECOLI,Escherichia coli (strain K12), comp135893_c3_seq2,2854,38.8227,0.44051126,0,0,,7.00E-40,Q9UHD2,Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1),Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1),GO:0005524; GO:0007249; GO:0035666; GO:0005829; GO:0050830; GO:0051607; GO:0010008; GO:0006954; GO:0045087; GO:0019048; GO:0010629; GO:0032480; GO:0003676; GO:0043123; GO:0032727; GO:0045359; GO:0032728; GO:0033138; GO:0045944; GO:0004674; GO:0009615; GO:0034138; GO:0034142; GO:0032606,ATP binding; I-kappaB kinase/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; cytosol; defense response to Gram-positive bacterium; defense response to virus; endosome membrane; inflammatory response; innate immune response; modulation by virus of host morphology or physiology; negative regulation of gene expression; negative regulation of type I interferon production; nucleic acid binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interferon-alpha production; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-beta production; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; response to virus; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; type I interferon production,PF00069;,,,,,,,,,TBK1_HUMAN,Homo sapiens (Human),defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon production [GO:0032480]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of xenophagy [GO:1904417]; regulation of neuron death [GO:1901214]; response to virus [GO:0009615]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon production [GO:0032606]; viral process [GO:0016032] comp135893_c3_seq4,1232,44.3182,0.46889164,0,0,,1.00E-36,Q6DFJ6,Serine/threonine-protein kinase TBK1 (EC 2.7.11.1),Serine/threonine-protein kinase TBK1 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0045087; GO:0004674,ATP binding; cytoplasm; innate immune response; protein serine/threonine kinase activity,PF00069;,,,,,,,,,TBK1_XENLA,Xenopus laevis (African clawed frog),innate immune response [GO:0045087] comp135893_c3_seq7,1184,44.5101,0.502119,0,0,,2.00E-29,Q9WUN2,Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1),Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1),GO:0005524; GO:0002218; GO:0005829; GO:0050830; GO:0051607; GO:0045087; GO:0010629; GO:0003676; GO:0043123; GO:0032727; GO:0045359; GO:0032728; GO:0045944; GO:0004674,ATP binding; activation of innate immune response; cytosol; defense response to Gram-positive bacterium; defense response to virus; innate immune response; negative regulation of gene expression; nucleic acid binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interferon-alpha production; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-beta production; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity,PF00069;,,,3.00E-47,ruditapes2_c2731,,,,,TBK1_MOUSE,Mus musculus (Mouse),activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of xenophagy [GO:1904417] comp135894_c0_seq1,2476,40.0242,0.26564103,0,0,,0,Q3TNA1,Xylulose kinase (Xylulokinase) (EC 2.7.1.17),Xylulose kinase (Xylulokinase) (EC 2.7.1.17),GO:0005524; GO:0042732; GO:0004856; GO:0005997,ATP binding; D-xylose metabolic process; xylulokinase activity; xylulose metabolic process,PF02782;PF00370;,,,,,,,,,XYLB_MOUSE,Mus musculus (Mouse),D-xylose metabolic process [GO:0042732]; xylulose metabolic process [GO:0005997] comp135894_c0_seq3,2476,39.9838,0.25649792,0,0,,0,Q3TNA1,Xylulose kinase (Xylulokinase) (EC 2.7.1.17),Xylulose kinase (Xylulokinase) (EC 2.7.1.17),GO:0005524; GO:0042732; GO:0004856; GO:0005997,ATP binding; D-xylose metabolic process; xylulokinase activity; xylulose metabolic process,PF02782;PF00370;,5.00E-88,CHOYP_BRAFLDRAFT_124284.1.1,,,,,,,XYLB_MOUSE,Mus musculus (Mouse),D-xylose metabolic process [GO:0042732]; xylulose metabolic process [GO:0005997] comp135894_c0_seq5,2360,39.5763,0.26361116,0,0,,,,,,,,,3.00E-65,CHOYP_BRAFLDRAFT_124284.1.1,,,,,,,,, comp135894_c0_seq6,2360,39.5339,0.25379745,0,0,,,,,,,,,,,5.00E-22,ruditapes_c28334,,,,,,, comp135895_c0_seq2,1504,43.617,0.28564663,78,168,,3.00E-23,Q9DCV6,Death ligand signal enhancer,Death ligand signal enhancer,GO:0008625; GO:0005739; GO:0043281,extrinsic apoptotic signaling pathway via death domain receptors; mitochondrion; regulation of cysteine-type endopeptidase activity involved in apoptotic process,PF08238;,4.00E-11,CHOYP_OLAH.2.2,,,,,,,DELE_MOUSE,Mus musculus (Mouse),extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281] comp135897_c0_seq2,703,42.8165,0.3207588,0,0,,4.00E-37,A6UV49,DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6),DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6),GO:0003677; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF04998;,,,7.00E-103,ruditapes_c19472,1.00E-91,AM866953.p.cg.6,4,,RPOA2_META3,Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3),"transcription, DNA-templated [GO:0006351]" comp135897_c0_seq3,2208,44.8822,0.41059827,128,195,,0,Q5ZL98,DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A),DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A),GO:0003677; GO:0003899; GO:0005634; GO:0032549; GO:0006351; GO:0008270,"DNA binding; DNA-directed RNA polymerase activity; nucleus; ribonucleoside binding; transcription, DNA-dependent; zinc ion binding",PF04997;PF00623;PF04983;PF05000;PF04998;,0,CHOYP_RPC1.1.1,,,,,,,RPC1_CHICK,Gallus gallus (Chicken),transcription from RNA polymerase III promoter [GO:0006383] comp135908_c0_seq1,3321,48.4493,0.55874718,232,111,,2.00E-41,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,0,CHOYP_LOC100876515.1.2,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp135908_c0_seq3,262,44.6565,0.53894228,3,0,,,,,,,,,2.00E-12,CHOYP_LOC100876515.1.2,,,,,,,,, comp135909_c0_seq2,2269,38.7395,1.06992303,8,3,,9.00E-09,P33765,Adenosine receptor A3,,GO:0001609; GO:0007190; GO:0002553; GO:0006954; GO:0005887; GO:0050850; GO:0050729; GO:0002687; GO:0043306; GO:0070257; GO:0014068; GO:0008016; GO:0007165,G-protein coupled adenosine receptor activity; activation of adenylate cyclase activity; histamine secretion by mast cell; inflammatory response; integral to plasma membrane; positive regulation of calcium-mediated signaling; positive regulation of inflammatory response; positive regulation of leukocyte migration; positive regulation of mast cell degranulation; positive regulation of mucus secretion; positive regulation of phosphatidylinositol 3-kinase cascade; regulation of heart contraction; signal transduction,,7.00E-35,CHOYP_LOC762961.3.5,,,,,,,AA3R_HUMAN,, comp135910_c0_seq3,1260,38.5714,0.2993829,85,33,,6.00E-28,Q95JY5,Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15),Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15),,,PF00536;,,,,,,,,,SAM15_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp135911_c7_seq2,2329,40.4895,0.44509746,10,26,,1.00E-23,O15226,NF-kappa-B-repressing factor (NFkB-repressing factor) (Protein ITBA4) (Transcription factor NRF),NF-kappa-B-repressing factor (NFkB-repressing factor) (Protein ITBA4) (Transcription factor NRF),GO:0003677; GO:0045892; GO:0005730; GO:0005634; GO:0006351,"DNA binding; negative regulation of transcription, DNA-dependent; nucleolus; nucleus; transcription, DNA-dependent",PF01585;PF01424;,,,,,,,,,NKRF_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp135912_c0_seq1,1569,43.9771,0.72650968,5,7,,5.00E-179,Q16875,"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]","6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]",GO:0003873; GO:0005524; GO:0005829; GO:0006003; GO:0006000; GO:0004331; GO:0006096; GO:0044281,"6-phosphofructo-2-kinase activity; ATP binding; cytosol; fructose 2,6-bisphosphate metabolic process; fructose metabolic process; fructose-2,6-bisphosphate 2-phosphatase activity; glycolysis; small molecule metabolic process",PF01591;PF00300;,,,,,,,,,F263_HUMAN,Homo sapiens (Human),"brain development [GO:0007420]; canonical glycolysis [GO:0061621]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]" comp135912_c0_seq2,1472,43.0707,0.71986988,4,27,,0,Q91309,"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2,6-P2ase) (PFK/FBPase) (6PF-2-K/Fru-2,6-P2ase liver/muscle isozymes) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]","6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2,6-P2ase) (PFK/FBPase) (6PF-2-K/Fru-2,6-P2ase liver/muscle isozymes) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]",GO:0003873; GO:0005524; GO:0006003; GO:0006000; GO:0004331,"6-phosphofructo-2-kinase activity; ATP binding; fructose 2,6-bisphosphate metabolic process; fructose metabolic process; fructose-2,6-bisphosphate 2-phosphatase activity",PF01591;PF00300;,7.00E-179,CHOYP_BRAFLDRAFT_277775.1.1,,,,,,,F26_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),"fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]" comp135916_c0_seq4,417,33.0935,0.70237749,6,18,,,,,,,,,,,2.00E-17,ruditapes2_c1165,,,,,,, comp135916_c0_seq6,447,37.1365,0.39384812,0,0,,,,,,,,,,,1.00E-22,ruditapes_c5455,,,,,,, comp135917_c0_seq1,1246,43.3387,0.5686121,3,0,,7.00E-37,P59895,Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6),Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6),GO:0005524; GO:0031572; GO:0006915; GO:0051301; GO:0007059; GO:0005737; GO:0000287; GO:0005815; GO:0007067; GO:0016607; GO:0018105; GO:0043123; GO:0046777; GO:0019901; GO:0004674; GO:0030071; GO:0004871; GO:0000922,ATP binding; G2 DNA damage checkpoint; apoptotic process; cell division; chromosome segregation; cytoplasm; magnesium ion binding; microtubule organizing center; mitosis; nuclear speck; peptidyl-serine phosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein autophosphorylation; protein kinase binding; protein serine/threonine kinase activity; regulation of mitotic metaphase/anaphase transition; signal transducer activity; spindle pole,PF00069;,,,,,,,,,NEK6_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitotic metaphase/anaphase transition [GO:0030071] comp135917_c0_seq2,3219,42.6841,0.72168344,0,0,,3.00E-133,P46549,Serine/threonine-protein kinase SULU (EC 2.7.11.1) (Protein kinase 18),Serine/threonine-protein kinase SULU (EC 2.7.11.1) (Protein kinase 18),GO:0005524; GO:0005938; GO:0007631; GO:0004674; GO:0043051,ATP binding; cell cortex; feeding behavior; protein serine/threonine kinase activity; regulation of pharyngeal pumping,PF00069;,4.00E-148,CHOYP_ISCW_ISCW014880.1.1,,,,,,,SULU_CAEEL,Caenorhabditis elegans,feeding behavior [GO:0007631]; negative regulation of MAP kinase activity [GO:0043407]; regulation of meiosis I [GO:0060631]; regulation of pharyngeal pumping [GO:0043051] comp135917_c0_seq3,2142,43.1373,0.63683504,0,0,,8.00E-178,O88664,Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1),Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1),GO:0005524; GO:0006281; GO:0031572; GO:0005737; GO:0097194; GO:0046330; GO:0030295; GO:0019901; GO:0004674; GO:0051493,ATP binding; DNA repair; G2 DNA damage checkpoint; cytoplasm; execution phase of apoptosis; positive regulation of JNK cascade; protein kinase activator activity; protein kinase binding; protein serine/threonine kinase activity; regulation of cytoskeleton organization,PF00069;,4.00E-164,CHOYP_ISCW_ISCW014880.1.1,1.00E-23,ruditapes_c15794,,,,,TAOK1_RAT,Rattus norvegicus (Rat),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; regulation of cytoskeleton organization [GO:0051493] comp135917_c0_seq4,3162,42.4731,0.72903024,0,0,,4.00E-134,P46549,Serine/threonine-protein kinase SULU (EC 2.7.11.1) (Protein kinase 18),Serine/threonine-protein kinase SULU (EC 2.7.11.1) (Protein kinase 18),GO:0005524; GO:0005938; GO:0007631; GO:0004674; GO:0043051,ATP binding; cell cortex; feeding behavior; protein serine/threonine kinase activity; regulation of pharyngeal pumping,PF00069;,,,,,,,,,SULU_CAEEL,Caenorhabditis elegans,feeding behavior [GO:0007631]; negative regulation of MAP kinase activity [GO:0043407]; regulation of meiosis I [GO:0060631]; regulation of pharyngeal pumping [GO:0043051] comp135917_c0_seq5,2199,43.4288,0.63027816,0,0,,1.00E-176,O88664,Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1),Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1),GO:0005524; GO:0006281; GO:0031572; GO:0005737; GO:0097194; GO:0046330; GO:0030295; GO:0019901; GO:0004674; GO:0051493,ATP binding; DNA repair; G2 DNA damage checkpoint; cytoplasm; execution phase of apoptosis; positive regulation of JNK cascade; protein kinase activator activity; protein kinase binding; protein serine/threonine kinase activity; regulation of cytoskeleton organization,PF00069;,,,,,,,,,TAOK1_RAT,Rattus norvegicus (Rat),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; regulation of cytoskeleton organization [GO:0051493] comp135918_c0_seq1,1255,40.3984,0.53826897,4,11,,2.00E-102,B6CZ17,G protein-coupled receptor kinase 7A (EC 2.7.11.14) (EC 2.7.11.16),Rhodopsin kinase 1 (EC 2.7.11.14) (G protein-coupled receptor kinase 7A),GO:0005524; GO:0004703; GO:0016020; GO:0050254; GO:0007165; GO:0038032; GO:0007601,ATP binding; G-protein coupled receptor kinase activity; membrane; rhodopsin kinase activity; signal transduction; termination of G-protein coupled receptor signaling pathway; visual perception,PF00069;PF00615;,,,,,,,,,GRK7A_XENLA,Xenopus laevis (African clawed frog),signal transduction [GO:0007165]; visual perception [GO:0007601] comp135918_c0_seq2,1314,40.6393,0.54599502,8,4,,2.00E-166,Q8VEB1,G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5),G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5),GO:0005524; GO:0004703; GO:0016055; GO:0006915; GO:0005737; GO:0008289; GO:0043066; GO:0005634; GO:0005886; GO:0046777; GO:0004674; GO:0007217; GO:0038032,ATP binding; G-protein coupled receptor kinase activity; Wnt receptor signaling pathway; apoptotic process; cytoplasm; lipid binding; negative regulation of apoptotic process; nucleus; plasma membrane; protein autophosphorylation; protein serine/threonine kinase activity; tachykinin receptor signaling pathway; termination of G-protein coupled receptor signaling pathway,PF00069;PF00615;,3.00E-150,CHOYP_GRK5.1.1,,,,,,,GRK5_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; desensitization of G-protein coupled receptor protein signaling pathway [GO:0002029]; fat cell differentiation [GO:0045444]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; response to drug [GO:0042493]; tachykinin receptor signaling pathway [GO:0007217]; Wnt signaling pathway [GO:0016055] comp135920_c0_seq1,1492,44.0349,0.48694483,5,0,,9.00E-21,Q95KD7,Coiled-coil domain-containing protein KIAA1407 homolog,Coiled-coil domain-containing protein 191,,,,,,,,,,,,K1407_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp135923_c2_seq10,995,44.7236,0.50388589,0,0,,,,,,,,,4.00E-53,CHOYP_ISCW_ISCW015934.1.1,,,,,,,,, comp135923_c2_seq11,660,48.0303,0.42192708,0,0,,,,,,,,,4.00E-76,CHOYP_LOC662190.3.3,,,,,,,,, comp135923_c2_seq13,255,40.3922,0.77225924,4,0,,,,,,,,,1.00E-20,CHOYP_DPER_GL12010.1.1,,,,,,,,, comp135923_c2_seq14,477,47.7987,0.59218224,4,4,,2.00E-06,Q9FUY2,Transcriptional corepressor LEUNIG,Transcriptional corepressor LEUNIG (Protein ROTUNDA2),GO:0030154; GO:0009908; GO:0045892; GO:0005634; GO:0006351,"cell differentiation; flower development; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF08513;PF00400;,,,,,,,,,LEUNG_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to external biotic stimulus [GO:0071217]; flower development [GO:0009908]; galacturonan metabolic process [GO:0010393]; meristem maintenance [GO:0010073]; mucilage extrusion from seed coat [GO:0080001]; mucilage metabolic process involved in seed coat development [GO:0048359]; negative regulation of transcription, DNA-templated [GO:0045892]; polarity specification of adaxial/abaxial axis [GO:0009944]; positive regulation of unidimensional cell growth [GO:0051512]; regulation of embryonic development [GO:0045995]; regulation of flower development [GO:0009909]; regulation of leaf development [GO:2000024]; regulation of shoot apical meristem development [GO:1902183]; response to auxin [GO:0009733]; response to bacterium [GO:0009617]; response to cycloheximide [GO:0046898]; response to fungus [GO:0009620]; response to hypoxia [GO:0001666]; response to nematode [GO:0009624]; response to oxidative stress [GO:0006979]; response to salt [GO:1902074]; response to silver ion [GO:0010272]; response to water deprivation [GO:0009414]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]" comp135923_c2_seq3,757,52.1797,0.50838452,6,0,,,,,,,,,9.00E-136,CHOYP_LOC662190.3.3,,,,,,,,, comp135923_c2_seq6,586,48.2935,0.38250738,0,0,,,,,,,,,1.00E-37,CHOYP_contig_052706,,,,,,,,, comp135923_c2_seq9,435,47.8161,0.60606381,1,0,,3.00E-59,Q9R050,Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein),Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein),GO:0005634; GO:0006355; GO:0003697; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; single-stranded DNA binding; transcription, DNA-dependent",,,,,,,,,,SSBP3_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135926_c1_seq1,1372,38.8484,1.06958783,5,424,,2.00E-26,Q6ZUK4,Transmembrane protein 26,Transmembrane protein 26,GO:0016021,integral to membrane,PF09772;,,,,,,,,,TMM26_HUMAN,Homo sapiens (Human), comp135929_c0_seq1,719,34.2142,0.4888325,39,554,,5.00E-10,Q6JQN1,Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),GO:0003995; GO:0050660; GO:0016787; GO:0005739; GO:0016772,"acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; hydrolase activity; mitochondrion; transferase activity, transferring phosphorus-containing groups",PF00441;PF02770;PF02771;PF01636;PF13419;,,,,,,,,,ACD10_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp135933_c0_seq5,889,40.7199,0.68167978,4,27,,8.00E-06,Q9K2B6,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_CHLPN,Chlamydia pneumoniae (Chlamydophila pneumoniae),menaquinone biosynthetic process [GO:0009234] comp135935_c0_seq1,2016,42.2123,1.05817771,3609,14,male>female,6.00E-141,Q6JEL2,Kelch-like protein 10,Kelch-like protein 10,GO:0000902; GO:0005737; GO:0009566; GO:0048873; GO:0048808; GO:0008584; GO:0016567; GO:0007286,cell morphogenesis; cytoplasm; fertilization; homeostasis of number of cells within a tissue; male genitalia morphogenesis; male gonad development; protein ubiquitination; spermatid development,PF07707;PF00651;PF01344;,8.00E-15,CHOYP_KLH10.1.1,,,,,,,KLH10_HUMAN,Homo sapiens (Human),cell morphogenesis [GO:0000902]; fertilization [GO:0009566]; homeostasis of number of cells within a tissue [GO:0048873]; male genitalia morphogenesis [GO:0048808]; male gonad development [GO:0008584]; protein ubiquitination [GO:0016567]; spermatid development [GO:0007286] comp135936_c0_seq1,1072,40.3918,0.4850818,0,0,,1.00E-90,Q5Y5T5,Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8),Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8),GO:0030659; GO:0016021; GO:0007626; GO:0005739; GO:0048471; GO:0016746; GO:0008270,"cytoplasmic vesicle membrane; integral to membrane; locomotory behavior; mitochondrion; perinuclear region of cytoplasm; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDHC8_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; regulation of mitophagy [GO:1903146] comp135936_c0_seq12,2757,38.9554,0.4975076,0,0,,1.00E-40,P59268,Palmitoyltransferase ZDHHC9 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 9) (DHHC-9) (DHHC9),Palmitoyltransferase ZDHHC9 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 9) (DHHC-9) (DHHC9),GO:0000139; GO:0005789; GO:0016021; GO:0016746; GO:0008270,"Golgi membrane; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDHC9_MOUSE,Mus musculus (Mouse),peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345] comp135936_c0_seq13,1024,40.332,0.52994034,0,0,,3.00E-90,Q5Y5T5,Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8),Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8),GO:0030659; GO:0016021; GO:0007626; GO:0005739; GO:0048471; GO:0016746; GO:0008270,"cytoplasmic vesicle membrane; integral to membrane; locomotory behavior; mitochondrion; perinuclear region of cytoplasm; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,4.00E-97,CHOYP_LOC100478743.1.1,,,,,,,ZDHC8_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; regulation of mitophagy [GO:1903146] comp135936_c0_seq7,2527,38.8207,0.45221739,0,0,,3.00E-89,Q5Y5T5,Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8),Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8),GO:0030659; GO:0016021; GO:0007626; GO:0005739; GO:0048471; GO:0016746; GO:0008270,"cytoplasmic vesicle membrane; integral to membrane; locomotory behavior; mitochondrion; perinuclear region of cytoplasm; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,1.00E-76,CHOYP_PHUM_PHUM098200.1.1,,,,,,,ZDHC8_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; regulation of mitophagy [GO:1903146] comp135936_c0_seq9,2602,38.8932,0.46796976,0,0,,6.00E-42,Q8IZN3,Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,1.00E-96,CHOYP_LOC100478743.1.1,,,,,,,ZDH14_HUMAN,Homo sapiens (Human),protein palmitoylation [GO:0018345] comp135938_c0_seq1,1014,40.3353,0.30029615,115,270,,5.00E-28,O76387,Probable peptidyl-tRNA hydrolase 2 (PTH 2) (EC 3.1.1.29),Probable peptidyl-tRNA hydrolase 2 (PTH 2) (EC 3.1.1.29),GO:0004045,aminoacyl-tRNA hydrolase activity,PF01981;PF00627;,3.00E-22,CHOYP_LOC100898860.1.1,,,,,,,PTH2_CAEEL,Caenorhabditis elegans, comp135942_c0_seq1,438,48.4018,0.7814905,0,57,,1.00E-08,Q9ES38,Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR),Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR),GO:0005524; GO:0009925; GO:0006699; GO:0008206; GO:0047747; GO:0015245; GO:0030176; GO:0043231; GO:0046951; GO:0015911; GO:0043234; GO:0032403; GO:0006642; GO:0000038; GO:0031957,ATP binding; basal plasma membrane; bile acid biosynthetic process; bile acid metabolic process; cholate-CoA ligase activity; fatty acid transporter activity; integral to endoplasmic reticulum membrane; intracellular membrane-bounded organelle; ketone body biosynthetic process; plasma membrane long-chain fatty acid transport; protein complex; protein complex binding; triglyceride mobilization; very long-chain fatty acid metabolic process; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,S27A5_RAT,Rattus norvegicus (Rat),bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; ketone body biosynthetic process [GO:0046951]; plasma membrane long-chain fatty acid transport [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038] comp135942_c0_seq2,539,46.5677,0.82506014,19,46,,6.00E-09,B2HI05,Long-chain-fatty-acid--CoA ligase FadD19 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase),Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligase (FACL) (EC 6.2.1.3) (EC 6.2.1.42) (Acyl-CoA synthetase) (Steroid-CoA ligase) (Steroid-coenzyme A ligase),GO:0005524; GO:0006633; GO:0001676; GO:0004467,ATP binding; fatty acid biosynthetic process; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,FAC19_MYCMM,Mycobacterium marinum (strain ATCC BAA-535 / M),cholesterol metabolic process [GO:0008203]; fatty acid biosynthetic process [GO:0006633] comp135942_c2_seq1,542,45.3875,0.67388536,0,0,,3.00E-55,Q6ETN3,Probable 4-coumarate--CoA ligase 3 (4CL 3) (Os4CL3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3),Probable 4-coumarate--CoA ligase 3 (4CL 3) (Os4CL3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,3.00E-14,CHOYP_BRAFLDRAFT_279625.1.1,,,,,,,4CL3_ORYSJ,Oryza sativa subsp. japonica (Rice),phenylpropanoid metabolic process [GO:0009698] comp135942_c2_seq3,352,42.8977,0.89562158,2,18,,3.00E-06,Q99NB1,"Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)","Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)",GO:0016208; GO:0005524; GO:0003987; GO:0006085; GO:0019427; GO:0005759,AMP binding; ATP binding; acetate-CoA ligase activity; acetyl-CoA biosynthetic process; acetyl-CoA biosynthetic process from acetate; mitochondrial matrix,PF16177;PF00501;PF13193;,,,,,,,,,ACS2L_MOUSE,Mus musculus (Mouse),acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate biosynthetic process [GO:0019542] comp135942_c2_seq7,576,44.2708,0.6351353,0,6,,7.00E-59,Q6ETN3,Probable 4-coumarate--CoA ligase 3 (4CL 3) (Os4CL3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3),Probable 4-coumarate--CoA ligase 3 (4CL 3) (Os4CL3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL3_ORYSJ,Oryza sativa subsp. japonica (Rice),phenylpropanoid metabolic process [GO:0009698] comp135944_c0_seq1,1684,47.8029,0.53104008,30,0,,6.00E-08,Q6EMB2,Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),GO:0006464; GO:0005813; GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0005634; GO:0006351,"cellular protein modification process; centrosome; cilium; cytoplasm; ligase activity; microtubule basal body; nucleus; transcription, DNA-dependent",PF03133;,,,,,,,,,TTLL5_HUMAN,Homo sapiens (Human),"fertilization [GO:0009566]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]" comp135944_c0_seq2,1666,48.0792,0.57215891,26,0,,,,,,,,,1.00E-37,CHOYP_contig_044341,,,,,,,,, comp135945_c0_seq1,1456,31.5247,0.22218844,104,462,,4.00E-10,Q9Y253,DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein),DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein),GO:0006260; GO:0000731; GO:0003887; GO:0005737; GO:0003684; GO:0046872; GO:0005654; GO:0006301; GO:0006290; GO:0006282; GO:0010225,DNA replication; DNA synthesis involved in DNA repair; DNA-directed DNA polymerase activity; cytoplasm; damaged DNA binding; metal ion binding; nucleoplasm; postreplication repair; pyrimidine dimer repair; regulation of DNA repair; response to UV-C,PF00817;PF11799;,,,,,,,,,POLH_HUMAN,Homo sapiens (Human),cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to UV-C [GO:0010225]; translesion synthesis [GO:0019985] comp135949_c0_seq12,1418,45.7687,0.83438445,0,0,,2.00E-06,Q8S897,BEL1-like homeodomain protein 5 (BEL1-like protein 5),BEL1-like homeodomain protein 5 (BEL1-like protein 5),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF05920;PF07526;,0,CHOYP_LOC100168368.1.1,,,,,,,BLH5_ARATH,Arabidopsis thaliana (Mouse-ear cress),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp135949_c0_seq18,361,43.7673,1.10650785,0,0,,3.00E-37,Q7PMT1,Homeobox protein extradenticle,Homeobox protein extradenticle,GO:0003677; GO:0001654; GO:0005634; GO:0007422; GO:0000060; GO:0006357; GO:0043565; GO:0003700; GO:0005667; GO:0006351,"DNA binding; eye development; nucleus; peripheral nervous system development; protein import into nucleus, translocation; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF00046;PF03792;,,,2.00E-35,ruditapes_c9428,,,,,EXD_ANOGA,Anopheles gambiae (African malaria mosquito),"eye development [GO:0001654]; peripheral nervous system development [GO:0007422]; protein import into nucleus, translocation [GO:0000060]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135949_c0_seq2,963,47.4559,0.82182527,0,0,,1.00E-123,Q7PMT1,Homeobox protein extradenticle,Homeobox protein extradenticle,GO:0003677; GO:0001654; GO:0005634; GO:0007422; GO:0000060; GO:0006357; GO:0043565; GO:0003700; GO:0005667; GO:0006351,"DNA binding; eye development; nucleus; peripheral nervous system development; protein import into nucleus, translocation; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF00046;PF03792;,5.00E-96,CHOYP_LOC100168368.1.1,,,,,,,EXD_ANOGA,Anopheles gambiae (African malaria mosquito),"eye development [GO:0001654]; peripheral nervous system development [GO:0007422]; protein import into nucleus, translocation [GO:0000060]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135949_c0_seq5,1500,47.0667,0.69064448,0,0,,,,,,,,,,,9.00E-131,ruditapes_c29200,,,,,,, comp135949_c0_seq8,1319,45.9439,0.82092334,0,0,,3.00E-122,Q7PMT1,Homeobox protein extradenticle,Homeobox protein extradenticle,GO:0003677; GO:0001654; GO:0005634; GO:0007422; GO:0000060; GO:0006357; GO:0043565; GO:0003700; GO:0005667; GO:0006351,"DNA binding; eye development; nucleus; peripheral nervous system development; protein import into nucleus, translocation; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF00046;PF03792;,,,,,,,,,EXD_ANOGA,Anopheles gambiae (African malaria mosquito),"eye development [GO:0001654]; peripheral nervous system development [GO:0007422]; protein import into nucleus, translocation [GO:0000060]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp135949_c0_seq9,1062,47.081,0.8398969,0,0,,,,,,,,,0,CHOYP_LOC100168368.1.1,,,,,,,,, comp135951_c0_seq1,2058,40.622,0.48676696,3,9,,0,Q26626,Kinesin-associated protein 3 (SpKAP115),Kinesin-associated protein 3 (SpKAP115),GO:0016939; GO:0007017,kinesin II complex; microtubule-based process,,0,CHOYP_LOC100371756.1.1,,,,,,,KIFA3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),microtubule-based process [GO:0007017] comp135951_c0_seq6,1199,41.0342,0.52094675,0,0,,0,Q26626,Kinesin-associated protein 3 (SpKAP115),Kinesin-associated protein 3 (SpKAP115),GO:0016939; GO:0007017,kinesin II complex; microtubule-based process,,,,,,,,,,KIFA3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),microtubule-based process [GO:0007017] comp135954_c0_seq1,1592,38.8819,0.36703546,875,3076,,1.00E-87,Q2YDF6,"28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt) (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt)","28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt) (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt)",GO:0005763,mitochondrial small ribosomal subunit,PF10213;,,,8.00E-37,ruditapes_c26599,,,,,RT35_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp135960_c0_seq1,1325,37.7358,0.6577069,70,1087,,3.00E-14,Q8K2D0,Protein FAM199X,Protein FAM199X,,,PF15814;,,,,,,,,,F199X_MOUSE,Mus musculus (Mouse), comp135962_c0_seq1,1693,38.925,0.52128928,13,100,,8.00E-85,Q8K4Q6,Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1),Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1),GO:0019104; GO:0006281; GO:0003906; GO:0006284; GO:0005694; GO:0005737; GO:0003684; GO:0016829; GO:0005815; GO:0032074; GO:0006289; GO:0005634; GO:0006979; GO:0008270,DNA N-glycosylase activity; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; base-excision repair; chromosome; cytoplasm; damaged DNA binding; lyase activity; microtubule organizing center; negative regulation of nuclease activity; nucleotide-excision repair; nucleus; response to oxidative stress; zinc ion binding,PF01149;PF06831;PF09292;,4.00E-18,CHOYP_LOC100703866.2.2,,,,,,,NEIL1_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; nucleotide-excision repair [GO:0006289]; response to oxidative stress [GO:0006979] comp135964_c0_seq1,2522,40.9596,1.14673221,0,168,,4.00E-161,Q9W265,"Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24)","Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24)",GO:0047988; GO:0046872; GO:0005739; GO:0015993,hydroxyacid-oxoacid transhydrogenase activity; metal ion binding; mitochondrion; molecular hydrogen transport,PF00465;,,,4.00E-74,ruditapes_c15690,,,,,HOT_DROME,Drosophila melanogaster (Fruit fly),molecular hydrogen transport [GO:0015993] comp135964_c0_seq2,2530,41.3439,1.12179871,30,226,,0,Q17EN4,"Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24)","Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24)",GO:0047988; GO:0046872; GO:0005739; GO:0015993,hydroxyacid-oxoacid transhydrogenase activity; metal ion binding; mitochondrion; molecular hydrogen transport,PF00465;,4.00E-52,CHOYP_LOC100691144.1.1,,,,,,,HOT_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),molecular hydrogen transport [GO:0015993] comp135973_c2_seq3,523,33.2696,0.49109833,25,109,,,,,,,,,,,2.00E-14,ruditapes_c22762,,,,,,, comp135976_c0_seq1,1626,35.0554,0.88488433,85,839,,2.00E-36,P54116,Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin),Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin),GO:0005856; GO:0070062; GO:0005887; GO:0042470; GO:0045121; GO:0051260,cytoskeleton; extracellular vesicular exosome; integral to plasma membrane; melanosome; membrane raft; protein homooligomerization,PF01145;,3.00E-31,CHOYP_LOC582981.1.1,2.00E-37,ruditapes_c11694,,,,,STOM_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of viral process [GO:0048524]; protein homooligomerization [GO:0051260]; regulation of acid-sensing ion channel activity [GO:1901585]; regulation of ion transmembrane transport [GO:0034765]; xenophagy [GO:0098792] comp135981_c0_seq2,1266,34.8341,0.37453571,0,0,,3.00E-31,Q9VBX1,Nuclear export mediator factor NEMF homolog (Protein Caliban),Nuclear export mediator factor NEMF homolog (Protein Caliban),GO:0005634; GO:0006611,nucleus; protein export from nucleus,PF11923;PF05670;,,,,,,,,,NEMF_DROME,Drosophila melanogaster (Fruit fly),protein export from nucleus [GO:0006611] comp135981_c0_seq3,2242,33.0955,0.6289173,0,0,,,,,,,,,4.00E-25,CHOYP_NEMF.1.1,,,,,,,,, comp135981_c0_seq6,458,35.3712,0.35904426,0,0,,,,,,,,,8.00E-26,CHOYP_NEMF.1.1,,,,,,,,, comp135981_c0_seq7,1294,34.544,0.37289204,0,0,,6.00E-31,Q9VBX1,Nuclear export mediator factor NEMF homolog (Protein Caliban),Nuclear export mediator factor NEMF homolog (Protein Caliban),GO:0005634; GO:0006611,nucleus; protein export from nucleus,PF11923;PF05670;,,,2.00E-12,ruditapes_c9915,,,,,NEMF_DROME,Drosophila melanogaster (Fruit fly),protein export from nucleus [GO:0006611] comp135982_c1_seq1,1877,42.4081,0.36780966,267,2155,,6.00E-102,Q3SZL5,GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein),GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein),GO:0042765; GO:0016255,GPI-anchor transamidase complex; attachment of GPI anchor to protein,PF10510;,2.00E-21,CHOYP_PIGS.1.1,1.00E-42,ruditapes_c19694,,,,,PIGS_BOVIN,Bos taurus (Bovine),attachment of GPI anchor to protein [GO:0016255] comp135987_c0_seq1,1520,40.1316,0.34380666,55,476,,3.00E-74,Q68FY1,Nucleoporin NUP53 (35 kDa nucleoporin) (Nuclear pore complex protein Nup53) (Nucleoporin Nup35),Nucleoporin NUP53 (35 kDa nucleoporin) (Nuclear pore complex protein Nup53) (Nucleoporin Nup35),GO:0051028; GO:0005652; GO:0031965; GO:0005643; GO:0015031; GO:0055085,mRNA transport; nuclear lamina; nuclear membrane; nuclear pore; protein transport; transmembrane transport,PF05172;,1.00E-36,CHOYP_LOC101064384.1.1,,,,,,,NUP53_RAT,Rattus norvegicus (Rat),"mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]; regulation of transcription, DNA-templated [GO:0006355]; transmembrane transport [GO:0055085]" comp135987_c0_seq2,455,40.4396,0.43615706,0,38,,,,,,,,,7.00E-14,CHOYP_LOC101064384.1.1,,,,,,,,, comp135991_c0_seq1,1139,43.7226,0.33583764,2,0,,1.00E-40,Q9X248,3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),GO:0004316; GO:0051287; GO:0050661; GO:0030497,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NAD binding; NADP binding; fatty acid elongation,,,,,,,,,,FABG_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),fatty acid elongation [GO:0030497] comp135991_c0_seq2,1152,43.6632,0.33269237,5,10,,7.00E-36,P50164,Tropinone reductase 2 (EC 1.1.1.236) (Tropinone reductase II) (TR-II),Tropinone reductase 2 (EC 1.1.1.236) (Tropinone reductase II) (TR-II),GO:0009710; GO:0050358,tropane alkaloid biosynthetic process; tropinone reductase activity,,3.00E-93,CHOYP_LOC100704819.2.2,5.00E-44,ruditapes2_c116,,,,,TRN2_HYONI,Hyoscyamus niger (Black henbane),tropane alkaloid biosynthetic process [GO:0009710] comp135991_c0_seq3,947,42.9778,0.36744227,0,0,,7.00E-13,P06235,Nodulation protein G (Host-specificity of nodulation protein C),Nodulation protein G (Host-specificity of nodulation protein C),GO:0009877; GO:0016491,nodulation; oxidoreductase activity,,,,,,,,,,NODG_RHIML,Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti),nodulation [GO:0009877] comp135991_c0_seq4,934,43.2548,0.36815595,0,0,,8.00E-30,Q937L4,Cyclopentanol dehydrogenase (EC 1.1.1.163),Cyclopentanol dehydrogenase (EC 1.1.1.163),GO:0033022; GO:0055041,cyclopentanol catabolic process; cyclopentanol dehydrogenase activity,,,,,,,,,,CPNA_COMTE,Comamonas testosteroni (Pseudomonas testosteroni),cyclopentanol catabolic process [GO:0033022] comp135994_c0_seq2,2080,47.9808,0.62723057,102,164,,6.00E-37,Q9Z340,Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP),Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP),GO:0044295; GO:0005938; GO:0007049; GO:0051301; GO:0005856; GO:0012505; GO:0090162; GO:0045197; GO:0016020; GO:0043025; GO:0005547; GO:0032266; GO:0005546; GO:0043234; GO:0006612; GO:0060341; GO:0005923; GO:0070830,"axonal growth cone; cell cortex; cell cycle; cell division; cytoskeleton; endomembrane system; establishment of epithelial cell polarity; establishment or maintenance of epithelial cell apical/basal polarity; membrane; neuronal cell body; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; protein complex; protein targeting to membrane; regulation of cellular localization; tight junction; tight junction assembly",PF12053;PF00595;,1.00E-30,CHOYP_LOC100371218.3.3,,,,,,,PARD3_RAT,Rattus norvegicus (Rat),bicellular tight junction assembly [GO:0070830]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341] comp135994_c0_seq3,547,47.8976,0.84447888,12,54,,2.00E-37,Q8TEW0,Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha),Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha),GO:0003383; GO:0045177; GO:0008356; GO:0044295; GO:0007409; GO:0005938; GO:0007049; GO:0005913; GO:0051642; GO:0005829; GO:0012505; GO:0090162; GO:0000226; GO:0043025; GO:0005547; GO:0032266; GO:0005546; GO:0005886; GO:0006461; GO:0007205; GO:0006612; GO:0032970; GO:0060341; GO:0005819; GO:0005923; GO:0070830; GO:0007179; GO:0044319,"apical constriction; apical part of cell; asymmetric cell division; axonal growth cone; axonogenesis; cell cortex; cell cycle; cell-cell adherens junction; centrosome localization; cytosol; endomembrane system; establishment of epithelial cell polarity; microtubule cytoskeleton organization; neuronal cell body; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; protein complex assembly; protein kinase C-activating G-protein coupled receptor signaling pathway; protein targeting to membrane; regulation of actin filament-based process; regulation of cellular localization; spindle; tight junction; tight junction assembly; transforming growth factor beta receptor signaling pathway; wound healing, spreading of cells",PF12053;PF00595;,,,,,,,,,PARD3_HUMAN,Homo sapiens (Human),asymmetric cell division [GO:0008356]; axonogenesis [GO:0007409]; bicellular tight junction assembly [GO:0070830]; cell cycle [GO:0007049]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein complex assembly [GO:0006461]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp135995_c0_seq1,891,42.1998,0.59091638,15,24,,4.00E-28,Q13451,Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase),GO:0005528; GO:0061077; GO:0005737; GO:0016020; GO:0005634; GO:0003755,FK506 binding; chaperone-mediated protein folding; cytoplasm; membrane; nucleus; peptidyl-prolyl cis-trans isomerase activity,PF00254;PF00515;PF13181;,,,4.00E-25,ruditapes_c17924,,,,,FKBP5_HUMAN,Homo sapiens (Human),chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457] comp135995_c0_seq2,1701,41.7402,0.46016598,98,247,,2.00E-59,A6QQ71,Peptidyl-prolyl cis-trans isomerase FKBP6 (PPIase FKBP6) (EC 5.2.1.8) (FK506-binding protein 6) (FKBP-6) (Rotamase),Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36),GO:0005528; GO:0016020; GO:0003755; GO:0006457,FK506 binding; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,6.00E-22,CHOYP_LOC100634891.1.1,,,,,,,FKBP6_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; meiotic nuclear division [GO:0007126]; piRNA metabolic process [GO:0034587]; protein folding [GO:0006457]; spermatogenesis [GO:0007283] comp135997_c0_seq5,941,43.0393,1.06216416,2,0,,1.00E-07,Q63180,Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Epididymal apical protein I) (EAP I),Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Epididymal apical protein I) (EAP I),GO:0016021; GO:0004222; GO:0006508; GO:0007283; GO:0008270,integral to membrane; metalloendopeptidase activity; proteolysis; spermatogenesis; zinc ion binding,PF08516;PF00200;PF01562;PF01421;,,,,,,,,,ADAM7_RAT,Rattus norvegicus (Rat), comp135998_c1_seq1,1336,41.5419,0.90389566,38,306,,1.00E-07,P86789,Gigasin-6,Gigasin-6,GO:0016021,integral to membrane,PF00144;,,,,,,,,,GIGA6_CRAGI,Crassostrea gigas (Pacific oyster) (Crassostrea angulata), comp136003_c2_seq1,856,36.7991,0.55343957,15,105,,,,,,,,,6.00E-12,CHOYP_contig_054064,,,,,,,,, comp136003_c2_seq10,360,33.6111,0.79167278,0,0,,,,,,,,,8.00E-12,CHOYP_LOC594533.1.1,,,,,,,,, comp136003_c2_seq11,538,32.7138,0.62934831,0,0,,,,,,,,,2.00E-15,CHOYP_contig_024441,,,,,,,,, comp136003_c2_seq12,443,40.4063,0.56923367,0,0,,,,,,,,,1.00E-11,CHOYP_contig_002281,,,,,,,,, comp136003_c2_seq13,275,36.7273,1.08321684,14,228,,,,,,,,,4.00E-14,CHOYP_contig_014968,8.00E-21,ruditapes_c4549,,,,,,, comp136003_c2_seq15,536,39.7388,0.57178549,0,0,,,,,,,,,2.00E-16,CHOYP_contig_036261,,,,,,,,, comp136003_c2_seq18,473,41.0148,0.61558717,0,0,,,,,,,,,1.00E-16,CHOYP_contig_036261,,,,,,,,, comp136003_c2_seq2,1374,43.8137,0.35004723,35,42,,5.00E-22,Q54WZ5,Probable inactive serine/threonine-protein kinase slob2 (Slowpoke-binding protein 2),Probable inactive serine/threonine-protein kinase slob2 (Slowpoke-binding protein 2),GO:0016021; GO:0016772,"integral to membrane; transferase activity, transferring phosphorus-containing groups",PF02205;,,,,,,,,,SLOB2_DICDI,Dictyostelium discoideum (Slime mold),negative regulation of ATPase activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; regulation of membrane potential [GO:0042391] comp136003_c2_seq3,1136,41.5493,0.42870257,0,2,,5.00E-98,Q8BX57,"PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)","PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)",GO:0005524; GO:0007154; GO:0005813; GO:0005737; GO:0006954; GO:0032780; GO:0043271; GO:0005634; GO:0035091; GO:0005886; GO:0004672; GO:0050804,ATP binding; cell communication; centrosome; cytoplasm; inflammatory response; negative regulation of ATPase activity; negative regulation of ion transport; nucleus; phosphatidylinositol binding; plasma membrane; protein kinase activity; regulation of synaptic transmission,PF00069;PF00787;PF02205;,2.00E-44,CHOYP_PXK.1.1,,,,,,,PXK_MOUSE,Mus musculus (Mouse),inflammatory response [GO:0006954]; modulation of synaptic transmission [GO:0050804]; negative regulation of ATPase activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; regulation of membrane potential [GO:0042391] comp136003_c2_seq4,762,38.4514,0.60748512,0,49,,,,,,,,,5.00E-12,CHOYP_contig_054064,,,,,,,,, comp136003_c2_seq5,508,31.6929,0.554641,0,0,,,,,,,,,1.00E-11,CHOYP_LOC594533.1.1,,,,,,,,, comp136003_c2_seq6,390,34.8718,0.84632591,0,0,,,,,,,,,1.00E-15,CHOYP_contig_024441,,,,,,,,, comp136003_c2_seq9,245,35.102,1.06958304,3,4,,,,,,,,,5.00E-13,CHOYP_contig_014968,,,,,,,,, comp136004_c1_seq1,935,38.1818,0.36538754,25,99,,8.00E-46,Q9H7Z3,Protein NRDE2 homolog,Protein NRDE2 homolog,,,PF08424;,,,,,,,,,CN102_HUMAN,Homo sapiens (Human),chromatin silencing by small RNA [GO:0031048]; RNA interference [GO:0016246] comp136005_c0_seq1,1764,39.1723,0.42198214,158,858,,8.00E-67,Q8RXN4,"3-hydroxyisobutyryl-CoA hydrolase-like protein 2, mitochondrial (EC 3.1.2.-)","3-hydroxyisobutyryl-CoA hydrolase-like protein 2, mitochondrial (EC 3.1.2.-)",GO:0016787; GO:0005739,hydrolase activity; mitochondrion,PF16113;,,,,,,,,,HIBC5_ARATH,Arabidopsis thaliana (Mouse-ear cress),fatty acid beta-oxidation [GO:0006635] comp136005_c0_seq2,1751,39.4061,0.41960855,3,320,,6.00E-160,A2VDC2,"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)","3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)",GO:0003860; GO:0005739; GO:0006574,3-hydroxyisobutyryl-CoA hydrolase activity; mitochondrion; valine catabolic process,PF16113;,3.00E-139,CHOYP_LOC100690782.1.1,,,,,,,HIBCH_XENLA,Xenopus laevis (African clawed frog),valine catabolic process [GO:0006574] comp136007_c0_seq1,1392,45.9052,0.34176351,4,14,,3.00E-41,Q8VCB2,Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25),Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25),GO:0048147; GO:0000122; GO:0005654; GO:0071158; GO:0035563; GO:2001178; GO:0045944; GO:0006351,"negative regulation of fibroblast proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of cell cycle arrest; positive regulation of chromatin binding; positive regulation of mediator complex assembly; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF11232;PF11244;PF11235;PF11265;,9.00E-38,CHOYP_MED25.2.2,,,,,,,MED25_MOUSE,Mus musculus (Mouse),"negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp136007_c0_seq2,1543,46.9864,0.29409536,0,0,,1.00E-40,Q71SY5,Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78),Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78),GO:0048147; GO:0000122; GO:0005654; GO:0071158; GO:0035563; GO:2001178; GO:0045944; GO:0006367,negative regulation of fibroblast proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; positive regulation of cell cycle arrest; positive regulation of chromatin binding; positive regulation of mediator complex assembly; positive regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter,PF11232;PF11244;PF11235;PF11265;,,,,,,,,,MED25_HUMAN,Homo sapiens (Human),negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp136007_c0_seq4,942,49.1507,0.31797271,0,0,,3.00E-42,Q6GP15,Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25),Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11232;PF11244;PF11235;PF11265;,,,,,,,,,MED25_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136007_c0_seq5,903,49.3909,0.31008916,0,0,,4.00E-17,Q9VDR1,Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (dmPTOV2),Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (dmPTOV2),GO:0001104; GO:0016592; GO:0007399; GO:0002805; GO:0006367,RNA polymerase II transcription cofactor activity; mediator complex; nervous system development; regulation of antimicrobial peptide biosynthetic process; transcription initiation from RNA polymerase II promoter,PF11232;PF11265;,,,,,,,,,MED25_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; regulation of antimicrobial peptide biosynthetic process [GO:0002805]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp136007_c0_seq6,752,47.8723,0.39785618,0,0,,,,,,,,,5.00E-38,CHOYP_MED25.2.2,,,,,,,,, comp136008_c0_seq1,1559,45.7344,0.54862865,35,237,,0,Q00944,Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (p41/p43FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK),Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (p41/p43FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK),GO:0005524; GO:0001525; GO:0005925; GO:0005815; GO:0004715; GO:0005634; GO:0018108; GO:0048471; GO:0005886; GO:0007172; GO:0004871; GO:0007165,ATP binding; angiogenesis; focal adhesion; microtubule organizing center; non-membrane spanning protein tyrosine kinase activity; nucleus; peptidyl-tyrosine phosphorylation; perinuclear region of cytoplasm; plasma membrane; signal complex assembly; signal transducer activity; signal transduction,PF00373;PF03623;PF07714;,1.00E-163,CHOYP_LOC100876637.2.2,,,,,,,FAK1_CHICK,Gallus gallus (Chicken),"actin filament organization [GO:0007015]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; innate immune response [GO:0045087]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of cell proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]" comp136010_c0_seq1,4498,39.8622,0.44452521,222,1048,,0,Q6DEY8,TBC1 domain family member 31 (WD repeat-containing protein 67),TBC1 domain family member 31 (WD repeat-containing protein 67),GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF00400;,0,CHOYP_WDR67.1.1,,,,,,,WDR67_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp136011_c0_seq3,790,32.4051,0.78321804,0,5,,2.00E-07,Q5R863,GPALPP motifs-containing protein 1,GPALPP motifs-containing protein 1,,,PF12572;,,,,,,,,,K1704_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp136011_c0_seq5,262,35.4962,0.99906489,11,98,,1.00E-08,Q4V893,GPALPP motifs-containing protein 1,GPALPP motifs-containing protein 1,,,PF12572;,,,,,,,,,K1704_RAT,Rattus norvegicus (Rat), comp136018_c0_seq1,1596,41.4787,0.23912341,137,702,,1.00E-21,A6NED2,RCC1 domain-containing protein 1,RCC1 domain-containing protein 1,GO:0005737; GO:0005886,cytoplasm; plasma membrane,PF00415;,,,,,,,,,RCCD1_HUMAN,Homo sapiens (Human), comp136020_c0_seq2,1027,46.7381,0.9496131,0,5,,3.00E-35,Q90421,LIM/homeobox protein Lhx3 (LIM homeobox protein 3) (Homeobox protein LIM-3),LIM/homeobox protein Lhx3 (LIM homeobox protein 3) (Homeobox protein LIM-3),GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;PF00412;,,,,,,,,,LHX3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron specification [GO:0021521]" comp136020_c0_seq4,1181,45.3006,0.92901119,0,179,,2.00E-44,Q8IRC7,LIM/homeobox protein Awh (Protein arrowhead),LIM/homeobox protein Awh (Protein arrowhead),GO:0048749; GO:0007444; GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"compound eye development; imaginal disc development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;PF00412;,,,,,,,,,AWH_DROME,Drosophila melanogaster (Fruit fly),"compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136023_c1_seq2,1150,41.0435,0.23512934,25,209,,1.00E-09,B5XF11,Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5),Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5),GO:0000086; GO:0003682; GO:0051864; GO:0046872; GO:0005634; GO:0045893; GO:0006351,"G2/M transition of mitotic cell cycle; chromatin binding; histone demethylase activity (H3-K36 specific); metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,1.00E-14,ruditapes_c19455,,,,,KDM8_SALSA,Salmo salar (Atlantic salmon),"G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-K36 demethylation [GO:0070544]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp136024_c0_seq2,3330,39.3694,0.60800608,504,3425,,0,Q5R7G6,Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1),Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1),GO:0004177; GO:0005737; GO:0030145; GO:0008235; GO:0006508,aminopeptidase activity; cytoplasm; manganese ion binding; metalloexopeptidase activity; proteolysis,PF00883;,6.00E-89,CHOYP_LOC656899.1.1,,,,,,,PEPL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp136027_c0_seq1,966,42.1325,0.5847323,78,290,,4.00E-68,Q8CHP8,Phosphoglycolate phosphatase (PGP) (PGPase) (EC 3.1.3.18),Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP),GO:0005975; GO:0016311; GO:0008967,carbohydrate metabolic process; dephosphorylation; phosphoglycolate phosphatase activity,PF13344;,,,,,,,,,PGP_MOUSE,Mus musculus (Mouse),dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335] comp136029_c1_seq1,1421,37.5088,1.08586512,0,9,,1.00E-12,P81282,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp136029_c1_seq3,1397,37.6521,1.0565056,2,62,,2.00E-18,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp136030_c0_seq1,909,40.5941,0.52125478,114,934,,3.00E-48,Q5I047,Protein FAM173B,Protein FAM173B,GO:0016021,integral to membrane,,,,1.00E-44,ruditapes_c23701,,,,,F173B_XENLA,Xenopus laevis (African clawed frog), comp136036_c5_seq1,463,50.324,1.09644582,14,55,,,,,,,,,4.00E-11,CHOYP_LOC100888608.1.3,7.00E-25,ruditapes2_c4751,,,,,,, comp136040_c2_seq1,1343,41.4743,0.33012739,114,119,,2.00E-07,Q09345,Polyadenylation and cleavage factor homolog 11,Polyadenylation and cleavage factor homolog 11,,,PF04818;,,,,,,,,,PCF11_CAEEL,Caenorhabditis elegans,mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369] comp136042_c0_seq1,682,43.5484,0.37187013,9,28,,3.00E-34,P16374,Zinc finger protein 60 (Zfp-60) (Zinc finger protein Mfg-3),Zinc finger protein 60 (Zfp-60) (Zinc finger protein Mfg-3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP60_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp136042_c0_seq3,406,42.3645,0.50075492,0,0,,7.00E-19,Q6ZMY9,Zinc finger protein 517,Zinc finger protein 517,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN517_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136044_c0_seq1,1776,43.5248,0.51653239,3573,11279,,5.00E-30,Q8C854,Myelin expression factor 2 (MEF-2) (MyEF-2),Myelin expression factor 2 (MEF-2) (MyEF-2),GO:0003677; GO:0003723; GO:0000166; GO:0005634; GO:0006351,"DNA binding; RNA binding; nucleotide binding; nucleus; transcription, DNA-dependent",PF00076;,4.00E-30,CHOYP_MYEF2.1.1,8.00E-50,ruditapes_c28497,,,,,MYEF2_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp136046_c0_seq1,1738,37.1116,0.51005062,830,5885,,1.00E-91,Q8AVY8,Estradiol 17-beta-dehydrogenase 12-B (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 12-B) (17-beta-HSD 12-B),Very-long-chain 3-oxoacyl-CoA reductase-B (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12-B) (17-beta-HSD 12-B) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12-B) (EC 1.1.1.62),GO:0005789; GO:0004303; GO:0006703; GO:0016021,endoplasmic reticulum membrane; estradiol 17-beta-dehydrogenase activity; estrogen biosynthetic process; integral to membrane,PF00106;,4.00E-30,CHOYP_DHB12.1.1,,,,,,,DH12B_XENLA,Xenopus laevis (African clawed frog),estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633] comp136047_c0_seq1,1806,41.6944,0.57694781,77,228,,1.00E-109,Q9Y6I7,WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1),WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1),GO:0005622; GO:0035556; GO:0016567,intracellular; intracellular signal transduction; protein ubiquitination,PF07525;PF00400;,,,,,,,,,WSB1_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; protein polyubiquitination [GO:0000209] comp136048_c0_seq1,1797,40.1781,0.41805865,22,116,,0,Q7ZVX6,NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3),NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3),GO:0005524; GO:0016881; GO:0045116; GO:0008641,ATP binding; acid-amino acid ligase activity; protein neddylation; small protein activating enzyme activity,PF08825;PF00899;,,,,,,,,,UBA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein neddylation [GO:0045116] comp136048_c0_seq2,1694,40.732,0.41634213,0,46,,0,Q7ZVX6,NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3),NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3),GO:0005524; GO:0016881; GO:0045116; GO:0008641,ATP binding; acid-amino acid ligase activity; protein neddylation; small protein activating enzyme activity,PF08825;PF00899;,0,CHOYP_UBA3.1.1,,,,,,,UBA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein neddylation [GO:0045116] comp136052_c0_seq2,1367,42.8676,0.51569154,0,0,,2.00E-50,O15014,Zinc finger protein 609,Zinc finger protein 609,GO:0046872; GO:0005634,metal ion binding; nucleus,,,,,,,,,,ZN609_HUMAN,Homo sapiens (Human), comp136052_c0_seq3,1198,45.3255,0.52443995,0,0,,4.00E-51,O15014,Zinc finger protein 609,Zinc finger protein 609,GO:0046872; GO:0005634,metal ion binding; nucleus,,,,,,,,,,ZN609_HUMAN,Homo sapiens (Human), comp136052_c0_seq4,1042,46.3532,0.57602483,0,0,,,,,,,,,2.00E-45,CHOYP_ZN609.1.1,,,,,,,,, comp136052_c0_seq7,1073,44.1752,0.48145069,0,0,,,,,,,,,,,7.00E-29,ruditapes_c465,,,,,,, comp136054_c1_seq1,1267,39.6212,0.48367279,224,205,,6.00E-43,B0S733,Regulator of nonsense transcripts 3A (Up-frameshift suppressor 3 homolog A),Regulator of nonsense transcripts 3A (Up-frameshift suppressor 3 homolog A),GO:0003723; GO:0005737; GO:0051028; GO:0000184; GO:0000166; GO:0005634,"RNA binding; cytoplasm; mRNA transport; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleotide binding; nucleus",PF03467;,8.00E-44,CHOYP_BRAFLDRAFT_70868.1.1,,,,,,,REN3A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp136055_c0_seq1,1842,30.2389,0.57865009,0,0,,9.00E-24,P59240,Nephrocystin-4 (Nephroretinin),Nephrocystin-4 (Nephroretinin),GO:0005911; GO:0005813; GO:0005929; GO:0005737; GO:0005932; GO:0060041; GO:0005923,cell-cell junction; centrosome; cilium; cytoplasm; microtubule basal body; retina development in camera-type eye; tight junction,,,,,,,,,,NPHP4_MOUSE,Mus musculus (Mouse),negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317] comp136055_c0_seq2,1897,29.4676,0.59266215,0,0,,,,,,,,,3.00E-14,CHOYP_BRAFLDRAFT_119906.1.1,,,,,,,,, comp136055_c1_seq1,1342,48.0626,0.50369308,20,10,,1.00E-86,P59240,Nephrocystin-4 (Nephroretinin),Nephrocystin-4 (Nephroretinin),GO:0005911; GO:0005813; GO:0005929; GO:0005737; GO:0005932; GO:0060041; GO:0005923,cell-cell junction; centrosome; cilium; cytoplasm; microtubule basal body; retina development in camera-type eye; tight junction,,,,,,,,,,NPHP4_MOUSE,Mus musculus (Mouse),negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317] comp136055_c1_seq2,1309,48.9687,0.53564158,24,0,,,,,,,,,1.00E-34,CHOYP_BRAFLDRAFT_119906.1.1,,,,,,,,, comp136065_c0_seq2,1951,43.1061,0.40371368,47,114,,4.00E-144,Q7TT28,RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1),RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1),GO:0004527; GO:0003676; GO:0090305; GO:0005634,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF15870;,4.00E-88,CHOYP_REXO1.1.1,,,,,,,REXO1_MOUSE,Mus musculus (Mouse), comp136065_c0_seq3,976,43.9549,0.3674724,3,0,,7.00E-37,O94443,Uncharacterized exonuclease C637.09 (EC 3.1.-.-),Uncharacterized exonuclease C637.09 (EC 3.1.-.-),GO:0008408; GO:0034476; GO:0000467; GO:0003676; GO:0005634; GO:0034415,"3'-5' exonuclease activity; U5 snRNA 3'-end processing; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleic acid binding; nucleus; tRNA 3'-trailer cleavage, exonucleolytic",PF00929;,,,,,,,,,YFE9_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA processing [GO:0006396]; tRNA 3'-trailer cleavage, exonucleolytic [GO:0034415]; U5 snRNA 3'-end processing [GO:0034476]" comp136069_c1_seq2,1700,36.4118,0.88910524,5,6,,1.00E-10,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp136072_c1_seq1,1067,44.2362,0.88221745,11,59,,3.00E-56,P54315,Inactive pancreatic lipase-related protein 1 (PL-RP1),Inactive pancreatic lipase-related protein 1 (PL-RP1),GO:0005509; GO:0005576; GO:0006629; GO:0004806,calcium ion binding; extracellular region; lipid metabolic process; triglyceride lipase activity,PF00151;PF01477;,,,,,,,,,LIPR1_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629] comp136072_c1_seq2,879,46.4164,0.84582962,0,8,,3.00E-48,Q6PA23,Lipase member H-A (EC 3.1.1.-),Lipase member H-A (EC 3.1.1.-),GO:0005576; GO:0016787; GO:0016042; GO:0016020,extracellular region; hydrolase activity; lipid catabolic process; membrane,PF00151;,,,2.00E-47,ruditapes_c11060,,,,,LIPHA_XENLA,Xenopus laevis (African clawed frog),lipid catabolic process [GO:0016042] comp136076_c0_seq2,1677,35.2415,0.39062332,1,4,,3.00E-17,Q54HX8,Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog),Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog),,,PF10601;,9.00E-39,CHOYP_NEMVEDRAFT_V1G129909.2.9,,,,,,,LITAH_DICDI,Dictyostelium discoideum (Slime mold), comp136076_c0_seq3,1922,36.7846,0.3407653,19,16,,3.00E-17,Q54HX8,Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog),Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog),,,PF10601;,1.00E-38,CHOYP_BCL3.2.2,,,,,,,LITAH_DICDI,Dictyostelium discoideum (Slime mold), comp136076_c0_seq4,1587,32.3882,0.62512137,11,61,,8.00E-18,Q8QGW7,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome),Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome),GO:0005125; GO:0005737; GO:0006355; GO:0006351,"cytokine activity; cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10601;,4.00E-11,CHOYP_NEMVEDRAFT_V1G129909.7.9,9.00E-74,ruditapes2_c3252,,,,,LITAF_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136076_c0_seq6,1605,32.7726,0.6036898,127,16,,,,,,,,,4.00E-18,CHOYP_NEMVEDRAFT_V1G99547.3.4,8.00E-62,ruditapes_c3601,,,,,,, comp136080_c0_seq1,1430,35.6643,0.35451522,88,211,,7.00E-113,B5XF11,Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5),Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5),GO:0000086; GO:0003682; GO:0051864; GO:0046872; GO:0005634; GO:0045893; GO:0006351,"G2/M transition of mitotic cell cycle; chromatin binding; histone demethylase activity (H3-K36 specific); metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",,6.00E-34,CHOYP_KDM8.1.1,,,,,,,KDM8_SALSA,Salmo salar (Atlantic salmon),"G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-K36 demethylation [GO:0070544]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp136081_c2_seq1,1387,45.566,0.4314235,97,245,,0,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,0,CHOYP_LOC100123553.1.1,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136083_c0_seq1,1541,43.9325,0.73525859,90,119,,5.00E-178,Q8IVL1,Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2),Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2),GO:0005524; GO:0021563; GO:0004386; GO:0008201; GO:0005614; GO:0007626; GO:0005634; GO:0021554; GO:0003025; GO:0007608; GO:0007605; GO:0021564,ATP binding; glossopharyngeal nerve development; helicase activity; heparin binding; interstitial matrix; locomotory behavior; nucleus; optic nerve development; regulation of systemic arterial blood pressure by baroreceptor feedback; sensory perception of smell; sensory perception of sound; vagus nerve development,PF00307;,0,CHOYP_NAV2.1.3,,,,,,,NAV2_HUMAN,Homo sapiens (Human),glossopharyngeal nerve development [GO:0021563]; locomotory behavior [GO:0007626]; optic nerve development [GO:0021554]; regulation of systemic arterial blood pressure by baroreceptor feedback [GO:0003025]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; vagus nerve development [GO:0021564] comp136083_c1_seq2,885,48.1356,0.74224081,2,0,,2.00E-24,Q5TZ18,Neuron navigator 3,Neuron navigator 3,GO:0005524; GO:0005640; GO:0017111,ATP binding; nuclear outer membrane; nucleoside-triphosphatase activity,PF00004;PF00307;,,,,,,,,,NAV3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),liver morphogenesis [GO:0072576]; pancreas development [GO:0031016] comp136084_c0_seq1,2050,41.6098,0.45452542,93,422,,6.00E-80,A0JMW6,Transmembrane protein 214-A,Transmembrane protein 214-A,GO:0006915; GO:0005881; GO:0005789; GO:0016021,apoptotic process; cytoplasmic microtubule; endoplasmic reticulum membrane; integral to membrane,PF10151;,,,,,,,,,T214A_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915] comp136085_c0_seq4,1609,50.0311,0.43819296,0,0,,2.00E-43,P59240,Nephrocystin-4 (Nephroretinin),Nephrocystin-4 (Nephroretinin),GO:0005911; GO:0005813; GO:0005929; GO:0005737; GO:0005932; GO:0060041; GO:0005923,cell-cell junction; centrosome; cilium; cytoplasm; microtubule basal body; retina development in camera-type eye; tight junction,,,,,,,,,,NPHP4_MOUSE,Mus musculus (Mouse),negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317] comp136085_c0_seq6,1576,50.698,0.42579354,0,0,,3.00E-29,O75161,Nephrocystin-4 (Nephroretinin),Nephrocystin-4 (Nephroretinin),GO:0030036; GO:0016337; GO:0005911; GO:0005813; GO:0005929; GO:0005829; GO:0035329; GO:0016020; GO:0005932; GO:0060041; GO:0005198; GO:0005923; GO:0007632,actin cytoskeleton organization; cell-cell adhesion; cell-cell junction; centrosome; cilium; cytosol; hippo signaling cascade; membrane; microtubule basal body; retina development in camera-type eye; structural molecule activity; tight junction; visual behavior,,,,,,,,,,NPHP4_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; hippo signaling [GO:0035329]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; sperm motility [GO:0030317]; visual behavior [GO:0007632] comp136089_c0_seq1,2185,41.9222,0.57061675,252,2288,,3.00E-25,Q9Y6X9,MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1),MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1),GO:0005524; GO:0005829; GO:0005634; GO:0008270,ATP binding; cytosol; nucleus; zinc ion binding,PF07496;,1.00E-44,CHOYP_MORC2.1.1,,,,,,,MORC2_HUMAN,Homo sapiens (Human),fatty acid metabolic process [GO:0006631] comp136090_c0_seq1,1284,37.6168,1.11043966,20,481,,4.00E-39,P56389,Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase),Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase),GO:0004126; GO:0030308; GO:0045980; GO:0001882; GO:0042803; GO:0051289; GO:0008270,cytidine deaminase activity; negative regulation of cell growth; negative regulation of nucleotide metabolic process; nucleoside binding; protein homodimerization activity; protein homotetramerization; zinc ion binding,PF00383;,1.00E-17,CHOYP_LOC100693418.1.2,3.00E-15,ruditapes_c15318,,,,,CDD_MOUSE,Mus musculus (Mouse),cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289] comp136096_c0_seq1,2700,32.2222,0.67229984,1,86,,1.00E-20,Q95YJ5,Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3),Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0030154; GO:0045454; GO:0007275; GO:0004550; GO:0007283,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cell differentiation; cell redox homeostasis; multicellular organismal development; nucleoside diphosphate kinase activity; spermatogenesis,PF00334;PF00085;,5.00E-19,CHOYP_NDK6.1.1,,,,,,,TXND3_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis),cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] comp136096_c0_seq2,2747,32.4354,0.67988901,0,22,,2.00E-51,B3DL53,Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6),Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0046872; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; metal ion binding; nucleoside diphosphate kinase activity,PF00334;,,,,,,,,,NDK6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] comp136099_c1_seq1,1966,36.47,0.38807264,9,13,,4.00E-25,Q8JZL3,Thiamine-triphosphatase (ThTPase) (EC 3.6.1.28),Thiamine-triphosphatase (ThTPase) (EC 3.6.1.28),GO:0005737; GO:0016311; GO:0046872; GO:0005730; GO:0050333; GO:0006772,cytoplasm; dephosphorylation; metal ion binding; nucleolus; thiamin-triphosphatase activity; thiamine metabolic process,PF01928;,,,,,,,,,THTPA_MOUSE,Mus musculus (Mouse),dephosphorylation [GO:0016311]; thiamine diphosphate metabolic process [GO:0042357]; thiamine metabolic process [GO:0006772] comp136100_c2_seq2,573,41.0122,0.46344827,50,214,,5.00E-34,Q9BUL9,Ribonuclease P protein subunit p25 (RNase P protein subunit p25) (EC 3.1.26.5),Ribonuclease P protein subunit p25 (RNase P protein subunit p25) (EC 3.1.26.5),GO:0003723; GO:0005813; GO:0005739; GO:0005634; GO:0004526; GO:0008033,RNA binding; centrosome; mitochondrion; nucleus; ribonuclease P activity; tRNA processing,PF01918;,2.00E-40,CHOYP_RPP25L.1.1,,,,,,,RPP25_HUMAN,Homo sapiens (Human),rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682] comp136105_c0_seq1,1043,39.6932,0.42136791,11,35,,5.00E-67,Q5R4D2,Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-),Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF00175;,,,,,,,,,OXND1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp136105_c0_seq2,1058,39.603,0.41685228,57,149,,1.00E-71,Q7T0X7,Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-),Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF00175;,,,,,,,,,OXND1_XENLA,Xenopus laevis (African clawed frog), comp136108_c0_seq2,895,36.9832,0.62856377,108,128,,1.00E-26,Q2NKT1,Profilin-4,Profilin-4,GO:0030036; GO:0005737; GO:0005856; GO:0008289,actin cytoskeleton organization; cytoplasm; cytoskeleton; lipid binding,PF00235;,8.00E-74,CHOYP_LOC100372995.1.3,,,,,,,PROF4_BOVIN,Bos taurus (Bovine),sequestering of actin monomers [GO:0042989] comp136112_c0_seq1,1543,44.0052,0.44844236,278,1834,,1.00E-157,Q4R7T7,Tubulin delta chain (Delta-tubulin),Tubulin delta chain (Delta-tubulin),GO:0005525; GO:0003924; GO:0030154; GO:0005814; GO:0005874; GO:0007017; GO:0007275; GO:0005634; GO:0051258; GO:0007283; GO:0005200,GTP binding; GTPase activity; cell differentiation; centriole; microtubule; microtubule-based process; multicellular organismal development; nucleus; protein polymerization; spermatogenesis; structural constituent of cytoskeleton,PF00091;,3.00E-107,CHOYP_LOC100378272.1.1,,,,,,,TBD_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell differentiation [GO:0030154]; microtubule-based process [GO:0007017]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp136117_c0_seq1,781,38.1562,0.45799057,81,389,,6.00E-35,Q9QZV9,NTF2-related export protein 1,NTF2-related export protein 1,GO:0006405; GO:0008536; GO:0005737; GO:0051028; GO:0005643; GO:0006611,RNA export from nucleus; Ran GTPase binding; cytoplasm; mRNA transport; nuclear pore; protein export from nucleus,PF02136;,,,2.00E-46,ruditapes_c11006,,,,,NXT1_MOUSE,Mus musculus (Mouse),mRNA transport [GO:0051028]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] comp136119_c2_seq7,1110,36.036,0.58504524,16,37,,,,,,,,,,,2.00E-24,ruditapes_c1695,,,,,,, comp136120_c0_seq1,2401,46.5639,0.53370052,145,105,,1.00E-22,Q6ZMW2,Zinc finger protein 782,Zinc finger protein 782,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,1.00E-120,CHOYP_ISCW_ISCW000803.1.1,,,,,,,ZN782_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136120_c0_seq2,811,44.3896,0.45675069,2,0,,8.00E-07,O75362,Zinc finger protein 217,Zinc finger protein 217,GO:0000118; GO:0046872; GO:0045892; GO:0003700; GO:0044212; GO:0006351,"histone deacetylase complex; metal ion binding; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",,,,,,,,,,ZN217_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp136121_c1_seq1,951,46.7928,0.58136285,2,0,,,,,,,,,1.00E-45,CHOYP_VWA8.3.3,,,,,,,,, comp136121_c1_seq2,977,46.2641,0.53919367,10,0,,9.00E-124,Q8CC88,von Willebrand factor A domain-containing protein 8,von Willebrand factor A domain-containing protein 8,GO:0005524; GO:0006200; GO:0016887; GO:0005576; GO:0005739,ATP binding; ATP catabolic process; ATPase activity; extracellular region; mitochondrion,PF07728;,2.00E-45,CHOYP_VWA8.3.3,,,,,,,VWA8_MOUSE,Mus musculus (Mouse), comp136121_c2_seq1,2023,46.0702,0.53305747,10,17,,,,,,,,,3.00E-84,CHOYP_VWA8.1.3,,,,,,,,, comp136121_c2_seq2,2514,46.7383,0.53949002,52,36,,0,A3KMH1,von Willebrand factor A domain-containing protein 8,von Willebrand factor A domain-containing protein 8,GO:0005524; GO:0006200; GO:0016887; GO:0005576; GO:0005739,ATP binding; ATP catabolic process; ATPase activity; extracellular region; mitochondrion,PF07728;,1.00E-147,CHOYP_VWA8.2.3,,,,,,,VWA8_HUMAN,Homo sapiens (Human), comp136133_c0_seq1,1460,38.5616,0.49837046,2,0,,1.00E-21,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp136140_c0_seq2,2111,37.1388,0.38628771,6,40,,9.00E-44,O94941,RING finger protein 37 (U-box domain-containing protein 5) (Ubiquitin-conjugating enzyme 7-interacting protein 5),RING finger protein 37 (EC 6.3.2.-) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) (hUIP5) (Ubiquitin-conjugating enzyme 7-interacting protein 5),GO:0005634; GO:0000209; GO:0000151; GO:0034450; GO:0008270,nucleus; protein polyubiquitination; ubiquitin ligase complex; ubiquitin-ubiquitin ligase activity; zinc ion binding,PF04564;,,,,,,,,,RNF37_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209] comp136141_c3_seq1,1884,48.5669,0.69459352,23,0,,1.00E-58,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,4.00E-50,CHOYP_LOC100367237.2.2,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp136141_c3_seq2,663,48.2655,0.62252573,24,13,,3.00E-08,Q9U308,Juxtamembrane domain-associated catenin (p120 catenin homolog),Juxtamembrane domain-associated catenin (p120 catenin homolog),GO:0007155; GO:0005913; GO:0010172; GO:0032956; GO:0032880,cell adhesion; cell-cell adherens junction; embryonic body morphogenesis; regulation of actin cytoskeleton organization; regulation of protein localization,PF00514;PF00041;,,,,,,,,,JAC1_CAEEL,Caenorhabditis elegans,embryonic body morphogenesis [GO:0010172]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; single organismal cell-cell adhesion [GO:0016337] comp136141_c3_seq3,1840,49.5109,0.64155675,7,4,,6.00E-37,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,4.00E-50,CHOYP_LOC100367237.2.2,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp136147_c0_seq1,1589,38.3889,0.48923096,941,2980,,5.00E-58,Q5REJ1,"28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt)","28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt)",GO:0003723; GO:0005739; GO:0005840; GO:0003735; GO:0006412,RNA binding; mitochondrion; ribosome; structural constituent of ribosome; translation,PF00333;PF03719;,,,,,,,,,RT05_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),translation [GO:0006412] comp136149_c1_seq2,223,32.287,0.35248545,2,9,,,,,,,,,,,4.00E-11,ruditapes_c4109,,,,,,, comp136149_c1_seq4,374,33.1551,0.29644481,6,45,,,,,,,,,,,6.00E-18,ruditapes2_c3017,,,,,,, comp136149_c1_seq6,288,31.9444,0.27367754,20,51,,,,,,,,,,,2.00E-16,ruditapes_c17260,,,,,,, comp136151_c0_seq2,491,31.7719,0.81349544,3,8,,,,,,,,,,,4.00E-15,ruditapes_c7836,,,,,,, comp136159_c0_seq1,704,27.8409,0.59619571,0,5,,,,,,,,,,,3.00E-12,ruditapes2_c2139,,,,,,, comp136160_c0_seq2,2156,43.1354,0.58227849,238,11,,9.00E-107,B2RC85,Radial spoke head 10 homolog B2,Radial spoke head 10 homolog B2,,,PF02493;,4.00E-165,CHOYP_LOC592857.1.1,,,,,,,R10B2_HUMAN,Homo sapiens (Human), comp136160_c0_seq3,693,45.0216,0.60114098,138,3,,2.00E-19,Q56YP2,Phosphatidylinositol 4-phosphate 5-kinase 1 (AtPIP5K1) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 1) (Diphosphoinositide kinase 1) (PtdIns(4)P-5-kinase 1),Phosphatidylinositol 4-phosphate 5-kinase 1 (AtPIP5K1) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 1) (Diphosphoinositide kinase 1) (PtdIns(4)P-5-kinase 1),GO:0016308; GO:0005524; GO:0051015; GO:0003785; GO:0005886; GO:0006950,1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; actin filament binding; actin monomer binding; plasma membrane; response to stress,PF02493;PF01504;,,,,,,,,,PI5K1_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp136169_c0_seq1,1211,40.6276,0.2630781,0,0,,,,,,,,,5.00E-46,CHOYP_NEMVEDRAFT_V1G92762.1.1,,,,,,,,, comp136169_c0_seq3,1268,40.3785,0.31233579,0,8,,6.00E-56,Q9WY68,Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7),Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7),GO:0008660; GO:0008152,1-aminocyclopropane-1-carboxylate deaminase activity; metabolic process,PF00291;,,,,,,,,,1A1D_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099), comp13616_c0_seq1,208,47.5962,1.45379792,0,6,,3.00E-15,O55071,Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19),Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2BJ_MOUSE,Mus musculus (Mouse),epoxygenase P450 pathway [GO:0019373] comp136170_c0_seq2,782,32.8645,0.52659661,119,321,,,,,,,,,,,2.00E-21,ruditapes2_c3064,,,,,,, comp136173_c1_seq6,979,42.3902,0.83298004,0,10,,7.00E-09,Q65I24,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_BACLD,Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46),menaquinone biosynthetic process [GO:0009234] comp136177_c0_seq1,584,42.2945,0.54797431,22,110,,3.00E-50,P13127,F-actin-capping protein subunit alpha-1 (Beta-actinin subunit I) (CapZ 36/32),F-actin-capping protein subunit alpha-1 (Beta-actinin subunit I) (CapZ 36/32),GO:0008290; GO:0071203; GO:0030018; GO:0030036; GO:0051693; GO:0005829,F-actin capping protein complex; WASH complex; Z disc; actin cytoskeleton organization; actin filament capping; cytosol,PF01267;,1.00E-37,CHOYP_LOC552486.1.1,3.00E-94,ruditapes_c15451,,,,,CAZA1_CHICK,Gallus gallus (Chicken),barbed-end actin filament capping [GO:0051016] comp136177_c0_seq2,610,37.377,0.56947726,37,167,,4.00E-58,Q9W2N0,F-actin-capping protein subunit alpha,F-actin-capping protein subunit alpha,GO:0008290; GO:0071203; GO:0007015; GO:0016324; GO:0051016; GO:0000902; GO:0005869; GO:0007294; GO:0007018; GO:0051490; GO:0006909; GO:0010591; GO:0035220,F-actin capping protein complex; WASH complex; actin filament organization; apical plasma membrane; barbed-end actin filament capping; cell morphogenesis; dynactin complex; germarium-derived oocyte fate determination; microtubule-based movement; negative regulation of filopodium assembly; phagocytosis; regulation of lamellipodium assembly; wing disc development,PF01267;,,,,,,,,,CAPZA_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; germarium-derived oocyte fate determination [GO:0007294]; microtubule-based movement [GO:0007018]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of JNK cascade [GO:0046329]; phagocytosis [GO:0006909]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; sensory perception of pain [GO:0019233]; wing disc development [GO:0035220] comp136179_c0_seq1,374,40.9091,0.4485678,6,0,,,,,,,,,2.00E-27,CHOYP_ERCC2.1.1,,,,,,,,, comp136179_c1_seq5,1612,43.7965,0.28588933,115,293,,0,O08811,TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein),TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein),GO:0051539; GO:0043139; GO:0005524; GO:0004003; GO:0003677; GO:0071817; GO:0008353; GO:0009650; GO:0007568; GO:0006915; GO:0030282; GO:0000075; GO:0008283; GO:0032289; GO:0007059; GO:0019907; GO:0005737; GO:0040016; GO:0043249; GO:0030198; GO:0035315; GO:0048820; GO:0060218; GO:0005675; GO:0001701; GO:0046872; GO:0035264; GO:0033683; GO:0043388; GO:0045944; GO:0009791; GO:0006979; GO:0021510; GO:0006366; GO:0006283,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; DNA binding; MMXD complex; RNA polymerase II carboxy-terminal domain kinase activity; UV protection; aging; apoptotic process; bone mineralization; cell cycle checkpoint; cell proliferation; central nervous system myelin formation; chromosome segregation; cyclin-dependent protein kinase activating kinase holoenzyme complex; cytoplasm; embryonic cleavage; erythrocyte maturation; extracellular matrix organization; hair cell differentiation; hair follicle maturation; hematopoietic stem cell differentiation; holo TFIIH complex; in utero embryonic development; metal ion binding; multicellular organism growth; nucleotide-excision repair, DNA incision; positive regulation of DNA binding; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; response to oxidative stress; spinal cord development; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF06733;PF06777;PF13307;,0,CHOYP_ERCC2.1.1,,,,,,,ERCC2_MOUSE,Mus musculus (Mouse),"aging [GO:0007568]; apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; cell proliferation [GO:0008283]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair cycle process [GO:0022405]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; skin development [GO:0043588]; spinal cord development [GO:0021510]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; UV protection [GO:0009650]" comp136180_c0_seq1,473,41.0148,0.81156061,18,83,,4.00E-43,Q9BZF2,Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7),Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7),GO:0005776; GO:0071397; GO:0015485; GO:0005829; GO:0006869; GO:0097038; GO:0005543; GO:0005886; GO:1901800,autophagic vacuole; cellular response to cholesterol; cholesterol binding; cytosol; lipid transport; perinuclear endoplasmic reticulum; phospholipid binding; plasma membrane; positive regulation of proteasomal protein catabolic process,PF01237;,,,,,,,,,OSBL7_HUMAN,Homo sapiens (Human),cellular response to cholesterol [GO:0071397]; lipid transport [GO:0006869]; positive regulation of proteasomal protein catabolic process [GO:1901800] comp136180_c1_seq1,1642,36.2363,0.50206873,60,283,,9.00E-89,Q9H1P3,Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2),Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2),GO:0015485; GO:0006869,cholesterol binding; lipid transport,PF01237;,2.00E-73,CHOYP_OSBL1.1.1,,,,,,,OSBL2_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869] comp136182_c0_seq2,1312,43.5976,0.43532904,133,22,,4.00E-63,Q3ZBG9,Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2),Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2),GO:0016021; GO:0046872,integral to membrane; metal ion binding,PF03803;,3.00E-55,CHOYP_PLS2.1.1,,,,,,,PLS2_BOVIN,Bos taurus (Bovine), comp136184_c0_seq2,1685,34.4807,0.24094328,46,159,,4.00E-66,Q2T9V8,D-tyrosyl-tRNA(Tyr) deacylase 1 (EC 3.1.-.-) (DNA-unwinding element-binding protein B) (DUE-B),D-tyrosyl-tRNA(Tyr) deacylase 1 (EC 3.1.-.-) (DNA-unwinding element-binding protein B) (DUE-B),GO:0019478; GO:0003677; GO:0006260; GO:0005737; GO:0016788; GO:0046872; GO:0005730,"D-amino acid catabolic process; DNA binding; DNA replication; cytoplasm; hydrolase activity, acting on ester bonds; metal ion binding; nucleolus",PF02580;,2.00E-71,CHOYP_LOC100556247.3.3,,,,,,,DTD1_BOVIN,Bos taurus (Bovine),D-amino acid catabolic process [GO:0019478]; DNA replication [GO:0006260]; tRNA metabolic process [GO:0006399] comp136186_c1_seq3,2190,38.9954,0.31359797,264,1908,,1.00E-123,F6V515,S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase),S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase),GO:0019509; GO:0017061; GO:0005737; GO:0005634; GO:0004645; GO:0006166,L-methionine salvage from methylthioadenosine; S-methyl-5-thioadenosine phosphorylase activity; cytoplasm; nucleus; phosphorylase activity; purine ribonucleoside salvage,PF01048;,2.00E-80,CHOYP_MTAP.1.1,,,,,,,MTAP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166] comp136196_c0_seq1,1531,40.627,0.58781342,170,1765,,2.00E-22,Q3SZP0,Interferon regulatory factor 1 (IRF-1),Interferon regulatory factor 1 (IRF-1),GO:0000978; GO:0006915; GO:0007050; GO:0035458; GO:0071260; GO:0005737; GO:0051607; GO:0060333; GO:0045590; GO:0045892; GO:0000790; GO:0005634; GO:0032728; GO:0045893; GO:2000564; GO:0034124; GO:0003700; GO:0006351,"RNA polymerase II core promoter proximal region sequence-specific DNA binding; apoptotic process; cell cycle arrest; cellular response to interferon-beta; cellular response to mechanical stimulus; cytoplasm; defense response to virus; interferon-gamma-mediated signaling pathway; negative regulation of regulatory T cell differentiation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nucleus; positive regulation of interferon-beta production; positive regulation of transcription, DNA-dependent; regulation of CD8-positive, alpha-beta T cell proliferation; regulation of MyD88-dependent toll-like receptor signaling pathway; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;,,,,,,,,,IRF1_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of cell proliferation [GO:0008285]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; transcription, DNA-templated [GO:0006351]" comp136197_c3_seq2,801,35.206,0.50546297,28,65,,7.00E-19,Q2S8Y5,Iron-sulfur cluster insertion protein ErpA,Iron-sulfur cluster insertion protein ErpA,GO:0005506; GO:0016226; GO:0051536; GO:0005198,iron ion binding; iron-sulfur cluster assembly; iron-sulfur cluster binding; structural molecule activity,PF01521;,2.00E-30,CHOYP_ISCA1.1.2,,,,,,,ERPA_HAHCH,Hahella chejuensis (strain KCTC 2396),iron-sulfur cluster assembly [GO:0016226] comp136197_c3_seq3,1031,37.4394,0.69030165,17,137,,2.00E-53,Q80W96,"Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA)","Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA)",GO:0050886; GO:0016226; GO:0051536; GO:0046872; GO:0005739; GO:0005198,endocrine process; iron-sulfur cluster assembly; iron-sulfur cluster binding; metal ion binding; mitochondrion; structural molecule activity,PF01521;,5.00E-33,CHOYP_ISCA1.1.2,,,,,,,ISCA1_RAT,Rattus norvegicus (Rat),endocrine process [GO:0050886]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; sulfur compound metabolic process [GO:0006790] comp136198_c0_seq1,1196,37.0401,0.41799873,215,458,,4.00E-69,Q8R023,Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68),Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68),GO:0031519; GO:0035518; GO:0006355; GO:0006351; GO:0008270,"PcG protein complex; histone H2A monoubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF16207;,1.00E-28,CHOYP_PCGF1.1.1,,,,,,,PCGF1_MOUSE,Mus musculus (Mouse),"histone H2A monoubiquitination [GO:0035518]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136200_c2_seq2,774,41.9897,0.94570018,0,0,,1.00E-56,Q8INF0,Soluble guanylate cyclase 88E (EC 4.6.1.2),Soluble guanylate cyclase 88E (EC 4.6.1.2),GO:0005525; GO:0006184; GO:0070025; GO:0004383; GO:0008074; GO:0020037; GO:0035556; GO:0046872; GO:0070026; GO:0019826; GO:0001666; GO:0000302,"GTP binding; GTP catabolic process; carbon monoxide binding; guanylate cyclase activity; guanylate cyclase complex, soluble; heme binding; intracellular signal transduction; metal ion binding; nitric oxide binding; oxygen sensor activity; response to hypoxia; response to reactive oxygen species",PF00211;PF07700;PF07701;,1.00E-27,CHOYP_LOC100872200.1.1,,,,,,,GCY8E_DROME,Drosophila melanogaster (Fruit fly),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302]; signal transduction [GO:0007165] comp136200_c2_seq3,408,42.1569,0.78708377,0,0,,,,,,,,,,,5.00E-19,ruditapes_c24567,,,,,,, comp136200_c2_seq4,1893,43.8457,0.90939884,0,0,,3.00E-178,P18293,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0005525; GO:0042417; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0048662; GO:0017046; GO:0005886; GO:0030828; GO:0004672; GO:0007168; GO:0050880,ATP binding; GTP binding; dopamine metabolic process; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of smooth muscle cell proliferation; peptide hormone binding; plasma membrane; positive regulation of cGMP biosynthetic process; protein kinase activity; receptor guanylyl cyclase signaling pathway; regulation of blood vessel size,PF01094;PF00211;PF07714;,2.00E-28,CHOYP_LOC100748515.1.1,,,,,,,ANPRA_MOUSE,Mus musculus (Mouse),cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880] comp136200_c2_seq5,1774,43.3484,0.9175126,0,0,,5.00E-143,P18293,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0005525; GO:0042417; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0048662; GO:0017046; GO:0005886; GO:0030828; GO:0004672; GO:0007168; GO:0050880,ATP binding; GTP binding; dopamine metabolic process; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of smooth muscle cell proliferation; peptide hormone binding; plasma membrane; positive regulation of cGMP biosynthetic process; protein kinase activity; receptor guanylyl cyclase signaling pathway; regulation of blood vessel size,PF01094;PF00211;PF07714;,,,,,,,,,ANPRA_MOUSE,Mus musculus (Mouse),cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880] comp136200_c2_seq6,655,40.3053,0.9797817,0,0,,2.00E-33,Q8INF0,Soluble guanylate cyclase 88E (EC 4.6.1.2),Soluble guanylate cyclase 88E (EC 4.6.1.2),GO:0005525; GO:0006184; GO:0070025; GO:0004383; GO:0008074; GO:0020037; GO:0035556; GO:0046872; GO:0070026; GO:0019826; GO:0001666; GO:0000302,"GTP binding; GTP catabolic process; carbon monoxide binding; guanylate cyclase activity; guanylate cyclase complex, soluble; heme binding; intracellular signal transduction; metal ion binding; nitric oxide binding; oxygen sensor activity; response to hypoxia; response to reactive oxygen species",PF00211;PF07700;PF07701;,2.00E-28,CHOYP_ANPRB.1.2,,,,,,,GCY8E_DROME,Drosophila melanogaster (Fruit fly),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302]; signal transduction [GO:0007165] comp136201_c0_seq1,1128,36.5248,0.45334975,73,877,,2.00E-77,Q7ZUH1,UPF0568 protein C14orf166 homolog,UPF0568 protein C14orf166 homolog,GO:0000993; GO:0045944; GO:0072669; GO:0006351,"RNA polymerase II core binding; positive regulation of transcription from RNA polymerase II promoter; tRNA-splicing ligase complex; transcription, DNA-dependent",PF10036;,9.00E-43,CHOYP_CN166.1.1,,,,,,,CN166_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp136201_c0_seq2,608,34.5395,0.33251523,12,263,,,,,,,,,2.00E-16,CHOYP_CN166.1.1,,,,,,,,, comp136202_c2_seq1,1165,42.4034,0.74547596,18,158,,4.00E-41,Q95M17,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,,,,,,,,,CHIA_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp136202_c2_seq4,578,43.0796,0.71112042,0,0,,9.00E-33,Q9BZP6,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902),GO:0006915; GO:0030246; GO:0006037; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0007586; GO:0005615; GO:0006955; GO:0003796; GO:0000272; GO:0090197; GO:0002532; GO:0001101; GO:0009620,apoptotic process; carbohydrate binding; cell wall chitin metabolic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; digestion; extracellular space; immune response; lysozyme activity; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response; response to acid; response to fungus,PF01607;PF00704;,,,,,,,,,CHIA_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cell wall chitin metabolic process [GO:0006037]; chitin catabolic process [GO:0006032]; chitin metabolic process [GO:0006030]; digestion [GO:0007586]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]; response to fungus [GO:0009620] comp136204_c1_seq1,835,44.7904,0.91161747,8,92,,4.00E-58,Q8K4C0,Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),GO:0004499; GO:0050661; GO:0005789; GO:0050660; GO:0016021,"N,N-dimethylaniline monooxygenase activity; NADP binding; endoplasmic reticulum membrane; flavin adenine dinucleotide binding; integral to membrane",PF00743;,,,,,,,,,FMO5_RAT,Rattus norvegicus (Rat),drug metabolic process [GO:0017144] comp136204_c3_seq1,571,44.4834,0.90278055,7,55,,2.00E-39,Q99518,Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2),Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2),GO:0004499; GO:0050661; GO:0070995; GO:0017144; GO:0005789; GO:0050660; GO:0016021; GO:0006082; GO:0072592; GO:0009404; GO:0006805,"N,N-dimethylaniline monooxygenase activity; NADP binding; NADPH oxidation; drug metabolic process; endoplasmic reticulum membrane; flavin adenine dinucleotide binding; integral to membrane; organic acid metabolic process; oxygen metabolic process; toxin metabolic process; xenobiotic metabolic process",PF00743;,4.00E-25,CHOYP_FMO5.3.6,,,,,,,FMO2_HUMAN,Homo sapiens (Human),drug metabolic process [GO:0017144]; NADPH oxidation [GO:0070995]; NADP metabolic process [GO:0006739]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] comp136204_c3_seq3,344,48.5465,0.81633343,3,28,,1.00E-07,Q8MP06,Senecionine N-oxygenase (SNO) (EC 1.14.13.101),Senecionine N-oxygenase (SNO) (EC 1.14.13.101),GO:0004499; GO:0050661; GO:0009820; GO:0005576; GO:0050660; GO:0051289; GO:0033784,"N,N-dimethylaniline monooxygenase activity; NADP binding; alkaloid metabolic process; extracellular region; flavin adenine dinucleotide binding; protein homotetramerization; senecionine N-oxygenase activity",PF00743;,,,,,,,,,SNO1_TYRJA,Tyria jacobaeae (Cinnabar moth),alkaloid metabolic process [GO:0009820]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289] comp136208_c0_seq1,877,45.7241,0.87363298,1424,15306,,7.00E-43,P35003,Chymotrypsin-like serine proteinase (EC 3.4.21.-),Chymotrypsin-like serine proteinase (EC 3.4.21.-),GO:0005615; GO:0006508; GO:0004252,extracellular space; proteolysis; serine-type endopeptidase activity,PF00089;,,,2.00E-15,ruditapes2_c6406,,,,,CTRL_HALRU,Haliotis rufescens (California red abalone), comp136210_c0_seq2,3141,39.446,0.45212186,1889,3395,,1.00E-52,Q5R9L3,Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2),Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2),GO:0003723; GO:0005622; GO:0051028; GO:0000166,RNA binding; intracellular; mRNA transport; nucleotide binding,PF02136;PF00076;,3.00E-130,CHOYP_BRAFLDRAFT_203026.1.1,,,,,,,G3BP2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028] comp136215_c1_seq2,1014,42.7022,1.13043588,0,0,,8.00E-13,A1ZA47,PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),GO:0030018; GO:0015629; GO:0051371; GO:0005927; GO:0030239; GO:0001952; GO:0008270,Z disc; actin cytoskeleton; muscle alpha-actinin binding; muscle tendon junction; myofibril assembly; regulation of cell-matrix adhesion; zinc ion binding,PF15936;PF00412;PF00595;,3.00E-16,CHOYP_SMP_006860.2.4.4,,,,,,,ZASP_DROME,Drosophila melanogaster (Fruit fly),muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952] comp136218_c0_seq1,964,39.834,1.12887624,19,531,,3.00E-06,Q9FMP5,Calcium-dependent protein kinase 17 (EC 2.7.11.1),Calcium-dependent protein kinase 17 (EC 2.7.11.1),GO:0005524; GO:0005509; GO:0005737; GO:0005886; GO:0046777; GO:0004674; GO:0080092,ATP binding; calcium ion binding; cytoplasm; plasma membrane; protein autophosphorylation; protein serine/threonine kinase activity; regulation of pollen tube growth,PF13499;PF00069;,,,8.00E-28,ruditapes_c5724,,,,,CDPKH_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of pollen tube growth [GO:0080092] comp136219_c0_seq2,955,39.6859,0.86889439,0,0,,7.00E-84,Q99260,GTP-binding protein YPT6,GTP-binding protein YPT6,GO:0005525; GO:0003924; GO:0005794; GO:0006886; GO:0005886; GO:0042147; GO:0007264,"GTP binding; GTPase activity; Golgi apparatus; intracellular protein transport; plasma membrane; retrograde transport, endosome to Golgi; small GTPase mediated signal transduction",PF00071;,4.00E-141,CHOYP_LOC100178081.1.1,,,,,,,YPT6_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; small GTPase mediated signal transduction [GO:0007264]" comp136219_c0_seq5,1117,36.974,0.75518733,0,0,,3.00E-126,Q1KME6,Ras-related protein Rab-6A,Ras-related protein Rab-6A,GO:0005525; GO:0003924; GO:0000139; GO:0022402; GO:0005813; GO:0000042; GO:0010824; GO:0042493; GO:0007264,GTP binding; GTPase activity; Golgi membrane; cell cycle process; centrosome; protein targeting to Golgi; regulation of centrosome duplication; response to drug; small GTPase mediated signal transduction,PF00071;,5.00E-141,CHOYP_LOC100178081.1.1,,,,,,,RAB6A_CHICK,Gallus gallus (Chicken),"intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to Golgi [GO:0000042]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; small GTPase mediated signal transduction [GO:0007264]" comp136225_c0_seq1,1976,44.4838,0.39178332,2,0,,5.00E-22,Q60989,E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),GO:0016055; GO:0005737; GO:0005829; GO:1990001; GO:0043066; GO:0043524; GO:0051402; GO:0005634; GO:0048471; GO:0043234; GO:0004842; GO:0008270,Wnt receptor signaling pathway; cytoplasm; cytosol; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; neuron apoptotic process; nucleus; perinuclear region of cytoplasm; protein complex; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,5.00E-17,CHOYP_LOC726172.1.1,,,,,,,XIAP_MOUSE,Mus musculus (Mouse),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055] comp136225_c0_seq2,2348,43.1005,0.37889041,13,1,,5.00E-34,Q24306,Apoptosis 1 inhibitor (EC 6.3.2.-) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (dIAP1) (Protein thread),Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread),GO:0019788; GO:0016055; GO:0048800; GO:0007298; GO:0008407; GO:0004869; GO:0005737; GO:0008354; GO:0097340; GO:1990001; GO:0043066; GO:0046673; GO:0005634; GO:0090263; GO:0031398; GO:0042787; GO:0045035; GO:0007289; GO:0004842; GO:0008270,NEDD8 ligase activity; Wnt receptor signaling pathway; antennal morphogenesis; border follicle cell migration; chaeta morphogenesis; cysteine-type endopeptidase inhibitor activity; cytoplasm; germ cell migration; inhibition of cysteine-type endopeptidase activity; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of compound eye retinal cell programmed cell death; nucleus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sensory organ precursor cell division; spermatid nucleus differentiation; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,6.00E-11,CHOYP_TIAP2.13.13,,,,,,,IAP1_DROME,Drosophila melanogaster (Fruit fly),antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055] comp136225_c0_seq3,2309,44.0017,0.37906144,10,0,,4.00E-34,Q24306,Apoptosis 1 inhibitor (EC 6.3.2.-) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (dIAP1) (Protein thread),Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread),GO:0019788; GO:0016055; GO:0048800; GO:0007298; GO:0008407; GO:0004869; GO:0005737; GO:0008354; GO:0097340; GO:1990001; GO:0043066; GO:0046673; GO:0005634; GO:0090263; GO:0031398; GO:0042787; GO:0045035; GO:0007289; GO:0004842; GO:0008270,NEDD8 ligase activity; Wnt receptor signaling pathway; antennal morphogenesis; border follicle cell migration; chaeta morphogenesis; cysteine-type endopeptidase inhibitor activity; cytoplasm; germ cell migration; inhibition of cysteine-type endopeptidase activity; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of compound eye retinal cell programmed cell death; nucleus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sensory organ precursor cell division; spermatid nucleus differentiation; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,3.00E-20,CHOYP_BIRC7.2.5,,,,,,,IAP1_DROME,Drosophila melanogaster (Fruit fly),antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055] comp136226_c0_seq3,1581,35.9266,0.7850438,52,602,,3.00E-07,Q9BXX0,EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10),EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10),GO:0007155; GO:0005581; GO:0030023; GO:0005576,cell adhesion; collagen; extracellular matrix constituent conferring elasticity; extracellular region,PF00386;PF07546;,,,,,,,,,EMIL2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136227_c1_seq7,934,30.1927,0.14605588,171,1273,,1.00E-07,Q27409,Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1),Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1),GO:0005576,extracellular region,,,,,,,,,,FP1_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp136229_c0_seq3,2691,38.6473,0.39443229,99,161,,8.00E-45,Q9VCP0,Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA),Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA),GO:0003677; GO:0070449; GO:0016021; GO:0007275; GO:0032968; GO:0006368,DNA binding; elongin complex; integral to membrane; multicellular organismal development; positive regulation of transcription elongation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter,PF06881;PF08711;,2.00E-17,CHOYP_LOC100698273.1.1,,,,,,,ELOA1_DROME,Drosophila melanogaster (Fruit fly),imaginal disc-derived wing vein specification [GO:0007474]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp136232_c0_seq2,2889,41.9868,0.41087532,120,73,,1.00E-06,A2AWL7,MAX gene-associated protein,MAX gene-associated protein,GO:0003677; GO:0071339; GO:0003700; GO:0005667; GO:0006351,"DNA binding; MLL1 complex; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF16059;PF00010;PF00907;,,,,,,,,,MGAP_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp136235_c0_seq1,1440,36.9444,0.42855343,1936,25,,,,,,,,,2.00E-71,CHOYP_SMP_143090.1.1,,,,,,,,, comp136235_c1_seq1,515,39.6117,0.67621223,25,280,,2.00E-28,Q5FWY3,Sel1 repeat-containing protein 1B (Beta-lactamase hcp-like protein),Cytochrome c oxidase assembly factor 7B (Beta-lactamase hcp-like protein) (Sel1 repeat-containing protein 1B),,,PF08238;,,,,,,,,,SEL1B_XENLA,Xenopus laevis (African clawed frog), comp136235_c1_seq2,415,38.0723,0.41935727,69,289,,4.00E-13,Q9ZMS0,Putative beta-lactamase HcpD (EC 3.5.2.6) (Cysteine-rich protein D) (Penicillin-binding protein 4) (PBP 4),Putative beta-lactamase HcpD (EC 3.5.2.6) (Cysteine-rich protein D) (Penicillin-binding protein 4) (PBP 4),GO:0008800; GO:0005576; GO:0046677,beta-lactamase activity; extracellular region; response to antibiotic,PF08238;,,,,,,,,,HCPD_HELPJ,Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99),response to antibiotic [GO:0046677] comp136238_c0_seq3,1467,42.3995,0.45853527,40,566,,5.00E-98,Q8K4F6,Putative methyltransferase NSUN5 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein homolog),Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein homolog),GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF01189;,2.00E-21,CHOYP_NEMVEDRAFT_V1G240471.1.1,,,,,,,NSUN5_MOUSE,Mus musculus (Mouse),rRNA base methylation [GO:0070475] comp136241_c0_seq2,1378,38.9695,0.72033864,13,13,,2.00E-16,P48317,Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1),Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1),GO:0000086; GO:0007050; GO:0005634; GO:0006974,G2/M transition of mitotic cell cycle; cell cycle arrest; nucleus; response to DNA damage stimulus,PF01248;,,,3.00E-41,ruditapes_c15240,,,,,GA45A_RAT,Rattus norvegicus (Rat),cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; G2/M transition of mitotic cell cycle [GO:0000086] comp136243_c0_seq1,366,45.9016,0.31425952,6,0,,3.00E-39,Q6ZQA0,Neurobeachin-like protein 2,Neurobeachin-like protein 2,GO:0005783; GO:0030220,endoplasmic reticulum; platelet formation,PF02138;PF15787;PF14844;PF00400;,8.00E-19,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,NBEL2_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596]; megakaryocyte development [GO:0035855]; platelet alpha granule organization [GO:0070889]; platelet formation [GO:0030220]; wound healing [GO:0042060] comp136243_c0_seq2,3998,43.972,0.28675414,294,171,,0,Q9W4E2,Neurobeachin (A-kinase anchor protein 550) (AKAP 550) (Protein rugose) (dAKAP550),Neurobeachin (A-kinase anchor protein 550) (AKAP 550) (Protein rugose) (dAKAP550),GO:0042675; GO:0005737; GO:0042462; GO:0016021; GO:0016319; GO:0007528; GO:0043025; GO:0008355; GO:0051018,compound eye cone cell differentiation; cytoplasm; eye photoreceptor cell development; integral to membrane; mushroom body development; neuromuscular junction development; neuronal cell body; olfactory learning; protein kinase A binding,PF02138;PF06469;PF15787;PF14844;PF00400;,0,CHOYP_LOC100646535.1.1,,,,,,,NBEA_DROME,Drosophila melanogaster (Fruit fly),compound eye cone cell differentiation [GO:0042675]; eye photoreceptor cell development [GO:0042462]; mushroom body development [GO:0016319]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; protein localization [GO:0008104]; short-term memory [GO:0007614] comp136243_c1_seq1,956,43.9331,0.26100029,60,30,,7.00E-09,P0C6P0,Putative protein BCL8 (Neurobeachin pseudogene 1),Putative protein BCL8 (Neurobeachin pseudogene 1),,,PF15787;,2.00E-132,CHOYP_LOC724172.1.1,,,,,,,BCL8_HUMAN,Homo sapiens (Human), comp136243_c2_seq1,371,47.4394,0.58254371,2,0,,,,,,,,,1.00E-16,CHOYP_PHUM_PHUM055020.1.1,,,,,,,,, comp136246_c0_seq3,2414,40.8036,1.00665283,0,0,,1.00E-94,P56652,Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH3_BOVIN,Bos taurus (Bovine),hyaluronan metabolic process [GO:0030212] comp136246_c0_seq7,2457,40.5372,1.01205887,0,0,,1.00E-94,P56652,Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH3_BOVIN,Bos taurus (Bovine),hyaluronan metabolic process [GO:0030212] comp136247_c0_seq1,2121,40.264,0.63987059,143,531,,1.00E-125,Q6AXQ5,"2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)","2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)",GO:0016787,hydrolase activity,PF03372;,,,,,,,,,PDE12_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397] comp136249_c2_seq2,722,30.1939,0.60935642,36,225,,,,,,,,,,,2.00E-20,ruditapes_c376,,,,,,, comp136250_c1_seq3,1692,39.8345,0.64137487,18,33,,1.00E-72,Q5PPZ9,Rap1 GTPase-GDP dissociation stimulator 1-B (Rap1gds1-B protein) (RalB-binding protein B) (XsmgGDS-B) (smgGDS-B),Rap1 GTPase-GDP dissociation stimulator 1-B (Rap1gds1-B protein) (RalB-binding protein B) (XsmgGDS-B) (smgGDS-B),GO:0005096; GO:0017160; GO:0005737; GO:0005856; GO:0043547; GO:0007264,GTPase activator activity; Ral GTPase binding; cytoplasm; cytoskeleton; positive regulation of GTPase activity; small GTPase mediated signal transduction,PF00514;,1.00E-29,CHOYP_GDS1B.1.1,,,,,,,GDS1B_XENLA,Xenopus laevis (African clawed frog),positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] comp136253_c0_seq1,1100,41.8182,0.91917198,7,991,female>male,7.00E-24,O75897,Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),GO:0050427; GO:0005829; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1C4_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923] comp136255_c0_seq1,1607,40.3236,0.52367836,78,738,,3.00E-25,Q53T59,HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3),HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3),GO:0007154; GO:0035091,cell communication; phosphatidylinositol binding,PF00787;,,,,,,,,,H1BP3_HUMAN,Homo sapiens (Human),regulation of apoptotic process [GO:0042981] comp136257_c0_seq1,1562,39.2446,0.89122145,164,828,,5.00E-42,P36017,Vacuolar protein sorting-associated protein 21 (GTP-binding protein YPT51) (Vacuolar protein-targeting protein 12),Vacuolar protein sorting-associated protein 21 (GTP-binding protein YPT51) (Vacuolar protein-targeting protein 12),GO:0005525; GO:0003924; GO:0006895; GO:0006897; GO:0010008; GO:0005770; GO:0032511; GO:0031966; GO:0036258; GO:0036010; GO:0006623; GO:0007264; GO:0000011,GTP binding; GTPase activity; Golgi to endosome transport; endocytosis; endosome membrane; late endosome; late endosome to vacuole transport via multivesicular body sorting pathway; mitochondrial membrane; multivesicular body assembly; protein localization to endosome; protein targeting to vacuole; small GTPase mediated signal transduction; vacuole inheritance,PF00071;,,,,,,,,,VPS21_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),endocytosis [GO:0006897]; Golgi to endosome transport [GO:0006895]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; multivesicular body assembly [GO:0036258]; protein localization to endosome [GO:0036010]; protein targeting to vacuole [GO:0006623]; reticulophagy [GO:0061709]; small GTPase mediated signal transduction [GO:0007264]; vacuole inheritance [GO:0000011] comp136261_c0_seq1,1976,44.1296,0.34895709,68,257,,2.00E-28,Q8BL74,General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta),General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta),GO:0003677; GO:0000127; GO:0006383,DNA binding; transcription factor TFIIIC complex; transcription from RNA polymerase III promoter,PF00400;,,,,,,,,,TF3C2_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]" comp136266_c0_seq1,2216,40.0722,0.6098883,0,0,,0,P30051,Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13),Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13),GO:0003677; GO:0003143; GO:0035329; GO:0048368; GO:0030903; GO:0005634; GO:0048339; GO:0045944; GO:0042127; GO:0003700; GO:0005667; GO:0006351,"DNA binding; embryonic heart tube morphogenesis; hippo signaling cascade; lateral mesoderm development; notochord development; nucleus; paraxial mesoderm development; positive regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent",PF01285;,,,,,,,,,TEAD1_MOUSE,Mus musculus (Mouse),"cellular response to retinoic acid [GO:0071300]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; hippo signaling [GO:0035329]; lateral mesoderm development [GO:0048368]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell proliferation [GO:0042127]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; transition between fast and slow fiber [GO:0014883]" comp136266_c0_seq10,2222,40.279,0.61302935,0,0,,8.00E-161,P30052,Protein scalloped,Protein scalloped,GO:0000980; GO:0055013; GO:0007049; GO:0001745; GO:0035329; GO:0007480; GO:0007476; GO:0046872; GO:0035331; GO:0005634; GO:0045944; GO:0003700; GO:0007525; GO:0072089; GO:0006351,"RNA polymerase II distal enhancer sequence-specific DNA binding; cardiac muscle cell development; cell cycle; compound eye morphogenesis; hippo signaling cascade; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing morphogenesis; metal ion binding; negative regulation of hippo signaling cascade; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; somatic muscle development; stem cell proliferation; transcription, DNA-dependent",PF01285;,,,,,,,,,SCAL_DROME,Drosophila melanogaster (Fruit fly),"cardiac muscle cell development [GO:0055013]; cell cycle [GO:0007049]; compound eye morphogenesis [GO:0001745]; epithelium development [GO:0060429]; germarium-derived egg chamber formation [GO:0007293]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; negative regulation of hippo signaling [GO:0035331]; nervous system development [GO:0007399]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart morphogenesis [GO:2000826]; sensory organ development [GO:0007423]; somatic muscle development [GO:0007525]; stem cell proliferation [GO:0072089]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]" comp136266_c0_seq2,2242,40.4103,0.6041826,0,0,,,,,,,,,1.00E-146,CHOYP_TEAD1.1.1,,,,,,,,, comp136266_c0_seq3,544,43.75,0.73123614,0,0,,1.00E-09,P18412,Ty transcription activator TEC1,Ty transcription activator TEC1,GO:0003677; GO:0001077; GO:0001135; GO:0001300; GO:0001403; GO:0005634; GO:0036003; GO:0010527; GO:0007124,"DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription factor recruiting transcription factor activity; chronological cell aging; invasive growth in response to glucose limitation; nucleus; positive regulation of transcription from RNA polymerase II promoter in response to stress; positive regulation of transposition, RNA-mediated; pseudohyphal growth",PF01285;,4.00E-18,CHOYP_TEAD4.1.1,,,,,,,TEC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"chronological cell aging [GO:0001300]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transposition, RNA-mediated [GO:0010527]; pseudohyphal growth [GO:0007124]" comp136266_c0_seq4,2402,41.2157,0.63909586,0,0,,0,P28347,Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13),Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13),GO:0003677; GO:0035329; GO:0005654; GO:0003700; GO:0006367,DNA binding; hippo signaling cascade; nucleoplasm; sequence-specific DNA binding transcription factor activity; transcription initiation from RNA polymerase II promoter,PF01285;,,,,,,,,,TEAD1_HUMAN,Homo sapiens (Human),hippo signaling [GO:0035329]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp136266_c0_seq5,550,44.5455,0.73437535,0,0,,6.00E-10,P18412,Ty transcription activator TEC1,Ty transcription activator TEC1,GO:0003677; GO:0001077; GO:0001135; GO:0001300; GO:0001403; GO:0005634; GO:0036003; GO:0010527; GO:0007124,"DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription factor recruiting transcription factor activity; chronological cell aging; invasive growth in response to glucose limitation; nucleus; positive regulation of transcription from RNA polymerase II promoter in response to stress; positive regulation of transposition, RNA-mediated; pseudohyphal growth",PF01285;,,,,,,,,,TEC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"chronological cell aging [GO:0001300]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transposition, RNA-mediated [GO:0010527]; pseudohyphal growth [GO:0007124]" comp136266_c0_seq8,570,44.9123,0.69740673,0,0,,,,,,,,,4.00E-18,CHOYP_TEAD4.1.1,,,,,,,,, comp136266_c0_seq9,2408,41.4037,0.64135839,0,0,,0,Q62296,Transcriptional enhancer factor TEF-3 (ETF-related factor 2) (ETFR-2) (TEA domain family member 4) (TEAD-4) (TEF-1-related factor 1) (TEF-1-related factor FR-19) (RTEF-1),Transcriptional enhancer factor TEF-3 (ETF-related factor 2) (ETFR-2) (TEA domain family member 4) (TEAD-4) (TEF-1-related factor 1) (TEF-1-related factor FR-19) (RTEF-1),GO:0003677; GO:0001708; GO:0007566; GO:0035329; GO:0005634; GO:0045944; GO:0003700; GO:0005667; GO:0006351; GO:0001830,"DNA binding; cell fate specification; embryo implantation; hippo signaling cascade; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent; trophectodermal cell fate commitment",PF01285;,0,CHOYP_TEAD1.1.1,,,,,,,TEAD4_MOUSE,Mus musculus (Mouse),blastocyst formation [GO:0001825]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; embryo implantation [GO:0007566]; hippo signaling [GO:0035329]; in utero embryonic development [GO:0001701]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; trophectodermal cell fate commitment [GO:0001830]; xenophagy [GO:0098792] comp136267_c0_seq1,1144,36.8881,0.43736692,41,223,,2.00E-43,P08761,Peptide methionine sulfoxide reductase (EC 1.8.4.11) (Ecdysone-induced protein 28/29 kDa) (Methionine-S-sulfoxide reductase) (Peptide-methionine (S)-S-oxide reductase),Peptide methionine sulfoxide reductase (EC 1.8.4.11) (Ecdysone-induced protein 28/29 kDa) (Methionine-S-sulfoxide reductase) (Peptide-methionine (S)-S-oxide reductase),GO:0034599; GO:0008340; GO:0048812; GO:0008113; GO:0035071; GO:0000096,cellular response to oxidative stress; determination of adult lifespan; neuron projection morphogenesis; peptide-methionine (S)-S-oxide reductase activity; salivary gland cell autophagic cell death; sulfur amino acid metabolic process,PF01625;,6.00E-20,CHOYP_PHUM_PHUM280830.1.1,2.00E-68,ruditapes_c16897,,,,,MSRA_DROME,Drosophila melanogaster (Fruit fly),autophagic cell death [GO:0048102]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; neuron projection morphogenesis [GO:0048812]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]; salivary gland cell autophagic cell death [GO:0035071]; sulfur amino acid metabolic process [GO:0000096] comp136277_c1_seq1,743,35.5316,0.39157966,0,0,,5.00E-40,Q8BGN2,UPF0462 protein C4orf33 homolog,UPF0462 protein C4orf33 homolog,,,,,,,,,,,,CD033_MOUSE,Mus musculus (Mouse), comp136277_c1_seq6,1036,37.8378,0.46845813,0,0,,2.00E-55,Q8BGN2,UPF0462 protein C4orf33 homolog,UPF0462 protein C4orf33 homolog,,,,,,,,,,,,CD033_MOUSE,Mus musculus (Mouse), comp136278_c2_seq14,929,36.4909,0.36084698,0,0,,8.00E-31,Q6AXL8,Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein),Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein),GO:0008380; GO:0006397; GO:0005681; GO:0008270,RNA splicing; mRNA processing; spliceosomal complex; zinc ion binding,PF00642;PF06220;,,,,,,,,,ZMAT5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp136278_c2_seq6,948,36.2869,0.35676731,0,0,,9.00E-31,Q6AXL8,Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein),Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein),GO:0008380; GO:0006397; GO:0005681; GO:0008270,RNA splicing; mRNA processing; spliceosomal complex; zinc ion binding,PF00642;PF06220;,,,,,,,,,ZMAT5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp136282_c0_seq2,598,42.6421,0.77523944,5,23,,3.00E-08,P21331,Nucleic-acid-binding protein from mobile element jockey (ORF1),Nucleic-acid-binding protein from mobile element jockey (ORF1),GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,PF07530;,,,,,,,,,GAGJ_DROFU,Drosophila funebris (Fruit fly), comp136283_c0_seq1,1491,39.3025,0.86615761,253,5008,,2.00E-29,Q00719,O-methyltransferase MdmC (EC 2.1.1.-),O-methyltransferase MdmC (EC 2.1.1.-),GO:0008171; GO:0017000; GO:0046872,O-methyltransferase activity; antibiotic biosynthetic process; metal ion binding,PF01596;,,,4.00E-40,ruditapes_c16088,,,,,MDMC_STRMY,Streptomyces mycarofaciens,antibiotic biosynthetic process [GO:0017000] comp136286_c1_seq1,887,44.8703,0.53816891,45,256,,4.00E-39,P16257,Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR),Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR),GO:0030325; GO:0007568; GO:0005497; GO:0048266; GO:0008503; GO:0071476; GO:0071222; GO:0071294; GO:0006821; GO:0060242; GO:0008347; GO:0016021; GO:0005741; GO:0060253; GO:0045019; GO:0032720; GO:0014012; GO:0043065; GO:0051928; GO:0060252; GO:0051901; GO:0010940; GO:2000379; GO:0050810; GO:0042493; GO:0010042; GO:0032570; GO:0033574; GO:0010266; GO:0006694,adrenal gland development; aging; androgen binding; behavioral response to pain; benzodiazepine receptor activity; cellular hypotonic response; cellular response to lipopolysaccharide; cellular response to zinc ion; chloride transport; contact inhibition; glial cell migration; integral to membrane; mitochondrial outer membrane; negative regulation of glial cell proliferation; negative regulation of nitric oxide biosynthetic process; negative regulation of tumor necrosis factor production; peripheral nervous system axon regeneration; positive regulation of apoptotic process; positive regulation of calcium ion transport; positive regulation of glial cell proliferation; positive regulation of mitochondrial depolarization; positive regulation of necrotic cell death; positive regulation of reactive oxygen species metabolic process; regulation of steroid biosynthetic process; response to drug; response to manganese ion; response to progesterone stimulus; response to testosterone stimulus; response to vitamin B1; steroid biosynthetic process,PF03073;,,,,,,,,,TSPO_RAT,Rattus norvegicus (Rat),adrenal gland development [GO:0030325]; aging [GO:0007568]; behavioral response to pain [GO:0048266]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; contact inhibition [GO:0060242]; establishment of protein localization to mitochondrion [GO:0072655]; glial cell migration [GO:0008347]; ion transport [GO:0006811]; lipid transport [GO:0006869]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of mitophagy [GO:1903147]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of steroid biosynthetic process [GO:0050810]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to manganese ion [GO:0010042]; response to pain [GO:0048265]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; steroid biosynthetic process [GO:0006694] comp136286_c1_seq2,633,45.6556,0.4253413,11,35,,1.00E-16,P17057,Protein CrtK,Protein CrtK,GO:0016117; GO:0015995; GO:0016021; GO:0015979; GO:0005886,carotenoid biosynthetic process; chlorophyll biosynthetic process; integral to membrane; photosynthesis; plasma membrane,PF03073;,5.00E-37,CHOYP_MITF.2.3,,,,,,,CRTK_RHOCB,Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003),carotenoid biosynthetic process [GO:0016117]; chlorophyll biosynthetic process [GO:0015995]; photosynthesis [GO:0015979] comp136286_c1_seq3,943,41.5695,0.36894257,3,90,,2.00E-36,P16257,Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR),Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR),GO:0030325; GO:0007568; GO:0005497; GO:0048266; GO:0008503; GO:0071476; GO:0071222; GO:0071294; GO:0006821; GO:0060242; GO:0008347; GO:0016021; GO:0005741; GO:0060253; GO:0045019; GO:0032720; GO:0014012; GO:0043065; GO:0051928; GO:0060252; GO:0051901; GO:0010940; GO:2000379; GO:0050810; GO:0042493; GO:0010042; GO:0032570; GO:0033574; GO:0010266; GO:0006694,adrenal gland development; aging; androgen binding; behavioral response to pain; benzodiazepine receptor activity; cellular hypotonic response; cellular response to lipopolysaccharide; cellular response to zinc ion; chloride transport; contact inhibition; glial cell migration; integral to membrane; mitochondrial outer membrane; negative regulation of glial cell proliferation; negative regulation of nitric oxide biosynthetic process; negative regulation of tumor necrosis factor production; peripheral nervous system axon regeneration; positive regulation of apoptotic process; positive regulation of calcium ion transport; positive regulation of glial cell proliferation; positive regulation of mitochondrial depolarization; positive regulation of necrotic cell death; positive regulation of reactive oxygen species metabolic process; regulation of steroid biosynthetic process; response to drug; response to manganese ion; response to progesterone stimulus; response to testosterone stimulus; response to vitamin B1; steroid biosynthetic process,PF03073;,,,,,,,,,TSPO_RAT,Rattus norvegicus (Rat),adrenal gland development [GO:0030325]; aging [GO:0007568]; behavioral response to pain [GO:0048266]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; contact inhibition [GO:0060242]; establishment of protein localization to mitochondrion [GO:0072655]; glial cell migration [GO:0008347]; ion transport [GO:0006811]; lipid transport [GO:0006869]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of mitophagy [GO:1903147]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of steroid biosynthetic process [GO:0050810]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to manganese ion [GO:0010042]; response to pain [GO:0048265]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; steroid biosynthetic process [GO:0006694] comp136289_c0_seq1,817,41.1261,0.69914635,0,0,,2.00E-57,P51957,Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2),Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2),GO:0005524; GO:0051301; GO:0046872; GO:0007067; GO:0005634; GO:0004674,ATP binding; cell division; metal ion binding; mitosis; nucleus; protein serine/threonine kinase activity,PF00069;,,,,,,,,,NEK4_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]" comp136289_c0_seq2,702,41.0256,0.78353522,0,0,,5.00E-27,P11837,G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis),G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis),GO:0005524; GO:0000086; GO:0051301; GO:0007059; GO:0043987; GO:0007067; GO:0005634; GO:0045840; GO:0004674,ATP binding; G2/M transition of mitotic cell cycle; cell division; chromosome segregation; histone H3-S10 phosphorylation; mitosis; nucleus; positive regulation of mitosis; protein serine/threonine kinase activity,PF00069;,,,,,,,,,NIMA_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-S10 phosphorylation [GO:0043987]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic nuclear division [GO:0045840]; protein phosphorylation [GO:0006468] comp136289_c0_seq3,468,40.812,0.52637726,0,0,,1.00E-13,O48963,Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl protein 1) (Root phototropism protein 1),Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl protein 1) (Root phototropism protein 1),GO:0005524; GO:0010181; GO:0009882; GO:0009986; GO:0009904; GO:0009903; GO:0009898; GO:0010362; GO:0000155; GO:0009638; GO:0046777; GO:0004674; GO:0018298; GO:0010155; GO:0010119; GO:0023014; GO:0005773,ATP binding; FMN binding; blue light photoreceptor activity; cell surface; chloroplast accumulation movement; chloroplast avoidance movement; internal side of plasma membrane; negative regulation of anion channel activity by blue light; phosphorelay sensor kinase activity; phototropism; protein autophosphorylation; protein serine/threonine kinase activity; protein-chromophore linkage; regulation of proton transport; regulation of stomatal movement; signal transduction by phosphorylation; vacuole,PF13426;PF00069;,,,,,,,,,PHOT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),chloroplast accumulation movement [GO:0009904]; chloroplast avoidance movement [GO:0009903]; circadian rhythm [GO:0007623]; intracellular signal transduction [GO:0035556]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; regulation of proton transport [GO:0010155]; regulation of stomatal movement [GO:0010119]; response to blue light [GO:0009637] comp136289_c0_seq5,353,40.5099,0.6428623,0,0,,3.00E-10,P87347,Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Fragment),Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Fragment),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,MOS_APTAU,Apteryx australis (Southern brown kiwi), comp136290_c0_seq1,1990,40.5528,0.22235878,27,96,,1.00E-54,B0JZ65,Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein),Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein),GO:0006260; GO:0005721; GO:0003682; GO:0016568; GO:0006325; GO:0005737; GO:0071169; GO:0008327; GO:0035064; GO:0005815; GO:0005664; GO:0031933,DNA replication; centromeric heterochromatin; chromatin binding; chromatin modification; chromatin organization; cytoplasm; establishment of protein localization to chromatin; methyl-CpG binding; methylated histone residue binding; microtubule organizing center; nuclear origin of replication recognition complex; telomeric heterochromatin,,4.00E-18,CHOYP_LRWD1.1.1,,,,,,,LRWD1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; DNA replication [GO:0006260]; establishment of protein localization to chromatin [GO:0071169] comp136290_c0_seq3,1367,40.3804,0.27304677,0,0,,2.00E-43,Q6GM71,Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein),Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein),GO:0006260; GO:0005721; GO:0003682; GO:0016568; GO:0006325; GO:0005737; GO:0071169; GO:0008327; GO:0035064; GO:0005815; GO:0005664; GO:0031933,DNA replication; centromeric heterochromatin; chromatin binding; chromatin modification; chromatin organization; cytoplasm; establishment of protein localization to chromatin; methyl-CpG binding; methylated histone residue binding; microtubule organizing center; nuclear origin of replication recognition complex; telomeric heterochromatin,,,,,,,,,,LRWD1_XENLA,Xenopus laevis (African clawed frog),chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; DNA replication [GO:0006260]; establishment of protein localization to chromatin [GO:0071169] comp136292_c0_seq1,2911,37.7533,0.74105633,188,95,,3.00E-62,P25323,Myosin light chain kinase A (MLCK-A) (EC 2.7.11.18),Myosin light chain kinase A (MLCK-A) (EC 2.7.11.18),GO:0005524; GO:0030898; GO:0019933; GO:0019934; GO:0005737; GO:0000281; GO:0004687; GO:0046777; GO:0050920,ATP binding; actin-dependent ATPase activity; cAMP-mediated signaling; cGMP-mediated signaling; cytoplasm; mitotic cytokinesis; myosin light chain kinase activity; protein autophosphorylation; regulation of chemotaxis,PF00069;,,,,,,,,,MYLKA_DICDI,Dictyostelium discoideum (Slime mold),cAMP-mediated signaling [GO:0019933]; cGMP-mediated signaling [GO:0019934]; mitotic cytokinesis [GO:0000281]; protein autophosphorylation [GO:0046777]; regulation of chemotaxis [GO:0050920] comp136292_c0_seq2,1463,41.9686,0.71046535,2,0,,7.00E-117,Q924X7,Serine/threonine-protein kinase 33 (EC 2.7.11.1),Serine/threonine-protein kinase 33 (EC 2.7.11.1),GO:0005524; GO:0048471; GO:0046777; GO:0004674,ATP binding; perinuclear region of cytoplasm; protein autophosphorylation; protein serine/threonine kinase activity,PF00069;,6.00E-72,CHOYP_STK33.1.1,,,,,,,STK33_MOUSE,Mus musculus (Mouse),protein autophosphorylation [GO:0046777] comp136300_c1_seq1,1322,36.1573,1.11681728,0,0,,5.00E-11,B1WB06,Methyltransferase-like protein 24 (EC 2.1.1.-),Methyltransferase-like protein 24 (EC 2.1.1.-),GO:0005576; GO:0008168,extracellular region; methyltransferase activity,PF13383;,,,,,,,,,MET24_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp136301_c0_seq1,1938,38.5449,0.52202558,555,2789,,3.00E-176,Q3KQF0,Cytosolic Fe-S cluster assembly factor nubp1-A (Nucleotide-binding protein 1-A) (NBP 1-A),Cytosolic Fe-S cluster assembly factor nubp1-A (Nucleotide-binding protein 1-A) (NBP 1-A),GO:0051539; GO:0005524; GO:0005829; GO:0016226; GO:0051536; GO:0046872; GO:0017111,"4 iron, 4 sulfur cluster binding; ATP binding; cytosol; iron-sulfur cluster assembly; iron-sulfur cluster binding; metal ion binding; nucleoside-triphosphatase activity",PF10609;,7.00E-117,CHOYP_NUBP1.1.1,,,,,,,NUP1A_XENLA,Xenopus laevis (African clawed frog),iron-sulfur cluster assembly [GO:0016226] comp136306_c1_seq1,1314,39.726,0.59849988,0,3,,6.00E-14,P32332,Mitochondrial oxaloacetate transport protein (Mitochondrial carrier protein PMT),Mitochondrial oxaloacetate transport protein (Mitochondrial carrier protein PMT),GO:0016021; GO:0034658; GO:0005743; GO:0000227; GO:0008271; GO:0008272,integral to membrane; isopropylmalate transmembrane transporter activity; mitochondrial inner membrane; oxaloacetate secondary active transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transport,PF00153;,,,,,,,,,OAC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),isopropylmalate transport [GO:0034659]; oxaloacetate transport [GO:0015729]; sulfate transport [GO:0008272]; translation [GO:0006412] comp136306_c1_seq2,1329,39.5034,0.6192891,6,9,,1.00E-10,Q12289,Mitochondrial carnitine carrier,Mitochondrial carnitine carrier,GO:0005476; GO:0006631; GO:0016021; GO:0005743,carnitine:acyl carnitine antiporter activity; fatty acid metabolic process; integral to membrane; mitochondrial inner membrane,PF00153;,,,,,,,,,CRC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),fatty acid metabolic process [GO:0006631]; translation [GO:0006412] comp136306_c1_seq3,1733,40.2193,0.52850194,35,43,,4.00E-101,Q922G0,Solute carrier family 25 member 36,Solute carrier family 25 member 36,GO:0016021; GO:0005743; GO:0005739; GO:0032355; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; response to estradiol stimulus; transmembrane transport,PF00153;,4.00E-62,CHOYP_LOC100169180.1.1,,,,,,,S2536_MOUSE,Mus musculus (Mouse),mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; pyrimidine nucleotide transport [GO:0006864]; regulation of mitochondrial membrane potential [GO:0051881]; translation [GO:0006412] comp136309_c0_seq1,793,38.7137,0.31333909,14,202,,1.00E-90,Q6TEN1,Ras-related protein Rap-1b,Ras-related protein Rap-1b,GO:0005525; GO:0003924; GO:0005911; GO:0060026; GO:0005829; GO:0005886; GO:0007264,GTP binding; GTPase activity; cell-cell junction; convergent extension; cytosol; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAP1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cartilage morphogenesis [GO:0060536]; chondrocyte intercalation involved in growth plate cartilage morphogenesis [GO:0003428]; convergent extension [GO:0060026]; heart development [GO:0007507]; small GTPase mediated signal transduction [GO:0007264]; somite rostral/caudal axis specification [GO:0032525]; somitogenesis [GO:0001756] comp136309_c0_seq2,1380,37.3913,0.48463559,0,0,,1.00E-48,P22278,Ras-like protein 1,Ras-like protein 1,GO:0005525; GO:0003924; GO:0005886; GO:0007264,GTP binding; GTPase activity; plasma membrane; small GTPase mediated signal transduction,PF00071;,1.00E-87,CHOYP_RAP1B.1.1,,,,,,,RAS1_MUCCL,Mucor circinelloides f. lusitanicus (Mucor racemosus var. lusitanicus),small GTPase mediated signal transduction [GO:0007264] comp136309_c0_seq5,1142,38.6165,0.50759217,0,0,,3.00E-26,Q75J93,Circularly permutated Ras protein 1 (DdiCPRas1),Circularly permutated Ras protein 1 (DdiCPRas1),GO:0030127; GO:0006888; GO:0005525; GO:0003924; GO:0006886; GO:0007264; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; GTP binding; GTPase activity; intracellular protein transport; small GTPase mediated signal transduction; zinc ion binding,PF00071;,,,,,,,,,CPAS1_DICDI,Dictyostelium discoideum (Slime mold),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264] comp136309_c0_seq6,881,39.6141,0.56050644,6,0,,2.00E-88,Q6TEN1,Ras-related protein Rap-1b,Ras-related protein Rap-1b,GO:0005525; GO:0003924; GO:0005911; GO:0060026; GO:0005829; GO:0005886; GO:0007264,GTP binding; GTPase activity; cell-cell junction; convergent extension; cytosol; plasma membrane; small GTPase mediated signal transduction,PF00071;,6.00E-88,CHOYP_RAP1B.1.1,,,,,,,RAP1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cartilage morphogenesis [GO:0060536]; chondrocyte intercalation involved in growth plate cartilage morphogenesis [GO:0003428]; convergent extension [GO:0060026]; heart development [GO:0007507]; small GTPase mediated signal transduction [GO:0007264]; somite rostral/caudal axis specification [GO:0032525]; somitogenesis [GO:0001756] comp136312_c0_seq1,1167,37.018,0.53677685,269,867,,3.00E-91,Q4QQV8,Charged multivesicular body protein 5 (Chromatin-modifying protein 5),Charged multivesicular body protein 5 (Chromatin-modifying protein 5),GO:0005829; GO:0010008; GO:0015031,cytosol; endosome membrane; protein transport,PF03357;,2.00E-96,CHOYP_CHMP5.1.1,,,,,,,CHMP5_RAT,Rattus norvegicus (Rat),cell separation after cytokinesis [GO:0000920]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; mitotic metaphase plate congression [GO:0007080]; multivesicular body sorting pathway [GO:0071985]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of receptor recycling [GO:0001919]; viral budding [GO:0046755] comp136314_c0_seq5,2787,34.1945,0.99463558,32,1331,,7.00E-51,Q7Z449,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0008219; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0097267; GO:0006805,aromatase activity; cell death; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; omega-hydroxylase P450 pathway; xenobiotic metabolic process,PF00067;,,,3.00E-20,ruditapes_c23998,,,,,CP2U1_HUMAN,Homo sapiens (Human),omega-hydroxylase P450 pathway [GO:0097267] comp136316_c0_seq1,1631,39.7302,0.56302309,55,428,,3.00E-39,Q9GZT4,Serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase),Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17),GO:0005524; GO:0008721; GO:0070179; GO:0003941; GO:0006563; GO:0007568; GO:0045177; GO:0007420; GO:0005509; GO:0005737; GO:0016594; GO:0000287; GO:0043025; GO:0005886; GO:0042803; GO:0051289; GO:0030170; GO:0042866; GO:0042493; GO:0032496; GO:0043278; GO:0030378; GO:0018114,ATP binding; D-serine ammonia-lyase activity; D-serine biosynthetic process; L-serine ammonia-lyase activity; L-serine metabolic process; aging; apical part of cell; brain development; calcium ion binding; cytoplasm; glycine binding; magnesium ion binding; neuronal cell body; plasma membrane; protein homodimerization activity; protein homotetramerization; pyridoxal phosphate binding; pyruvate biosynthetic process; response to drug; response to lipopolysaccharide; response to morphine; serine racemase activity; threonine racemase activity,PF00291;,,,,,,,,,SRR_HUMAN,Homo sapiens (Human),aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; serine family amino acid metabolic process [GO:0009069] comp136317_c1_seq1,2042,37.5122,0.58386039,513,837,,4.00E-22,Q7ZYR8,Arginine/serine-rich coiled-coil protein 2,Arginine/serine-rich coiled-coil protein 2,,,PF15477;,5.00E-24,CHOYP_RSRC2.1.1,,,,,,,RSRC2_XENLA,Xenopus laevis (African clawed frog), comp136318_c0_seq3,1797,34.0011,0.7978141,8,25,,6.00E-53,Q5R651,14-3-3 protein zeta/delta,14-3-3 protein zeta/delta,GO:0042470,melanosome,PF00244;,2.00E-47,CHOYP_1433G.1.2,1.00E-35,ruditapes_c8999,,,,,1433Z_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp136318_c0_seq4,2198,34.4404,0.78138341,148,245,,2.00E-62,Q8AVQ3,14-3-3 protein beta/alpha-B,14-3-3 protein beta/alpha-B,GO:0005737,cytoplasm,PF00244;,4.00E-19,CHOYP_1433E.2.2,,,,,,,143BB_XENLA,Xenopus laevis (African clawed frog), comp136324_c0_seq1,951,40.9043,0.43129778,673,5128,,3.00E-17,P30284,G2/mitotic-specific cyclin-B,G2/mitotic-specific cyclin-B,GO:0000086; GO:0051301; GO:0016538; GO:0007067; GO:0005730; GO:0000079; GO:0005816,G2/M transition of mitotic cell cycle; cell division; cyclin-dependent protein serine/threonine kinase regulator activity; mitosis; nucleolus; regulation of cyclin-dependent protein serine/threonine kinase activity; spindle pole body,PF02984;PF00134;,,,,,,,,,CG21_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp136324_c1_seq1,2230,35.3812,0.46050451,4471,35511,,2.00E-105,P04962,G2/mitotic-specific cyclin-A,G2/mitotic-specific cyclin-A,GO:0051301; GO:0007067; GO:0005634; GO:0000079,cell division; mitosis; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;PF16500;,8.00E-41,CHOYP_CCNA.1.1,,,,,,,CCNA_SPISO,Spisula solidissima (Atlantic surf-clam),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp136328_c0_seq1,817,40.5141,0.98561561,6,315,,1.00E-08,P86729,Ependymin-related protein 2,Ependymin-related protein 2,GO:0005509; GO:0007160; GO:0005576,calcium ion binding; cell-matrix adhesion; extracellular region,PF00811;,,,,,,,,,EPDR2_HALAI,Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone),cell-matrix adhesion [GO:0007160] comp136332_c6_seq1,1627,39.4591,0.39537226,133,149,,7.00E-103,P13051,Uracil-DNA glycosylase (UDG) (EC 3.2.2.27),Uracil-DNA glycosylase (UDG) (EC 3.2.2.27),GO:0006284; GO:0005739; GO:0019048; GO:0005634; GO:0016446; GO:0016447; GO:0004844,base-excision repair; mitochondrion; modulation by virus of host morphology or physiology; nucleus; somatic hypermutation of immunoglobulin genes; somatic recombination of immunoglobulin gene segments; uracil DNA N-glycosylase activity,PF03167;,3.00E-70,CHOYP_LOC100708100.1.1,,,,,,,UNG_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of isotype switching [GO:0045830]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; viral process [GO:0016032]" comp136333_c0_seq2,1403,46.1155,0.53663598,0,0,,1.00E-75,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,,,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp136333_c1_seq1,2586,48.2212,0.4925135,65,17,,0,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,2.00E-175,CHOYP_LOC100166052.1.1,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp136333_c1_seq2,1846,48.6457,0.5778297,0,0,,,,,,,,,4.00E-132,CHOYP_LOC100166052.1.1,,,,,,,,, comp136333_c3_seq1,1640,47.622,0.55963504,86,99,,1.00E-37,A2AAE1,Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog),GO:0060612; GO:0045444; GO:0016021; GO:0006629; GO:0019915; GO:0005634; GO:0051647; GO:0001558; GO:0007283,adipose tissue development; fat cell differentiation; integral to membrane; lipid metabolic process; lipid storage; nucleus; nucleus localization; regulation of cell growth; spermatogenesis,PF10479;,,,,,,,,,K1109_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp136337_c0_seq1,595,36.4706,0.47085807,80,535,,6.00E-27,Q5BJI6,Ribonuclease P/MRP protein subunit POP5 (EC 3.1.26.5),Ribonuclease P/MRP protein subunit POP5 (EC 3.1.26.5),GO:0005730; GO:0004526; GO:0008033,nucleolus; ribonuclease P activity; tRNA processing,PF01900;,,,,,,,,,POP5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein lipoylation [GO:0009249]; tRNA processing [GO:0008033] comp136340_c0_seq1,1176,42.9422,0.2971474,51,218,,8.00E-86,Q9CYU6,Diphthamide biosynthesis protein 7 (DPH7) (WD repeat-containing protein 85),Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (DPH7) (WD repeat-containing protein 85),GO:0017183,peptidyl-diphthamide biosynthetic process from peptidyl-histidine,,1.00E-28,CHOYP_LOC101168963.1.2,,,,,,,WDR85_MOUSE,Mus musculus (Mouse),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp136344_c0_seq1,378,40.2116,0.32899536,4,3,,,,,,,,,,,1.00E-14,ruditapes_c12215,,,,,,, comp136344_c0_seq2,480,45.4167,0.49651828,28,26,,1.00E-69,P07902,Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase),Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase),GO:0005794; GO:0006258; GO:0008108; GO:0005829; GO:0019388; GO:0044281; GO:0008270,Golgi apparatus; UDP-glucose catabolic process; UDP-glucose:hexose-1-phosphate uridylyltransferase activity; cytosol; galactose catabolic process; small molecule metabolic process; zinc ion binding,PF02744;PF01087;,3.00E-57,CHOYP_LOC100693867.1.1,,,,,,,GALT_HUMAN,Homo sapiens (Human),galactose catabolic process [GO:0019388]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258] comp136344_c0_seq3,231,48.9177,0.36570673,14,19,,1.00E-24,P09580,Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase),Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase),GO:0008108; GO:0006012; GO:0008270,UDP-glucose:hexose-1-phosphate uridylyltransferase activity; galactose metabolic process; zinc ion binding,PF02744;PF01087;,,,,,,,,,GAL7_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),galactose catabolic process via UDP-galactose [GO:0033499] comp136344_c0_seq4,725,42.2069,0.37628025,3,0,,1.00E-49,Q03249,Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase),Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase),GO:0005794; GO:0006258; GO:0008108; GO:0006012; GO:0008270,Golgi apparatus; UDP-glucose catabolic process; UDP-glucose:hexose-1-phosphate uridylyltransferase activity; galactose metabolic process; zinc ion binding,PF02744;PF01087;,,,,,,,,,GALT_MOUSE,Mus musculus (Mouse),galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] comp136347_c1_seq1,919,33.9499,0.64436464,90,542,,2.00E-69,Q9CQP2,Trafficking protein particle complex subunit 2 (Sedlin),Trafficking protein particle complex subunit 2 (Sedlin),GO:0006888; GO:0005794; GO:0005783; GO:0005634; GO:0048471; GO:0006355; GO:0008134; GO:0006351,"ER to Golgi vesicle-mediated transport; Golgi apparatus; endoplasmic reticulum; nucleus; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF04628;,3.00E-92,CHOYP_BRAFLDRAFT_279668.1.1,1.00E-100,ruditapes_c22022,,,,,TPPC2_MOUSE,Mus musculus (Mouse),"ER to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]" comp136348_c0_seq1,2843,43.1235,0.44674127,28,32,,2.00E-166,Q5VZK9,Leucine-rich repeat-containing protein 16A (CARMIL homolog),"F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)",GO:0007015; GO:0007596; GO:0016477; GO:0005829; GO:0030027; GO:0030032; GO:0005634; GO:0031529; GO:0046415,actin filament organization; blood coagulation; cell migration; cytosol; lamellipodium; lamellipodium assembly; nucleus; ruffle organization; urate metabolic process,PF16000;PF13516;,1.00E-51,CHOYP_LR16A.1.3,,,,,,,LR16A_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415] comp136348_c0_seq2,1800,43.6667,0.38505606,0,0,,3.00E-122,Q3UFQ8,Leucine-rich repeat-containing protein 16B,"Capping protein, Arp2/3 and myosin-I linker protein 3 (Capping protein regulator and myosin 1 linker protein 3) (Leucine-rich repeat-containing protein 16B)",GO:0005737,cytoplasm,PF16000;PF13516;,,,,,,,,,LR16B_MOUSE,Mus musculus (Mouse), comp136348_c0_seq5,1771,43.5912,0.38131371,11,0,,6.00E-151,Q5VZK9,Leucine-rich repeat-containing protein 16A (CARMIL homolog),"F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)",GO:0007015; GO:0007596; GO:0016477; GO:0005829; GO:0030027; GO:0030032; GO:0005634; GO:0031529; GO:0046415,actin filament organization; blood coagulation; cell migration; cytosol; lamellipodium; lamellipodium assembly; nucleus; ruffle organization; urate metabolic process,PF16000;PF13516;,9.00E-52,CHOYP_LR16A.1.3,,,,,,,LR16A_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415] comp136349_c0_seq2,936,36.2179,0.78306378,78,185,,3.00E-42,P91454,Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 21),Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 21),GO:0016021; GO:0005743; GO:0005739; GO:0015031,integral to membrane; mitochondrial inner membrane; mitochondrion; protein transport,,3.00E-23,CHOYP_LOC100560768.1.1,4.00E-25,ruditapes_c7217,,,,,TIM14_CAEEL,Caenorhabditis elegans,protein transport [GO:0015031] comp136354_c0_seq2,1020,44.1176,0.59694418,281,1103,,4.00E-101,A5PLK2,Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (EC 3.1.3.-) (EC 3.6.1.1),Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (EC 3.1.3.-) (EC 3.6.1.1),GO:0005829; GO:0004427; GO:0000287; GO:0005634; GO:0008969; GO:0006470,cytosol; inorganic diphosphatase activity; magnesium ion binding; nucleus; phosphohistidine phosphatase activity; protein dephosphorylation,PF13344;,,,,,,,,,LHPP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phosphate-containing compound metabolic process [GO:0006796]; protein dephosphorylation [GO:0006470] comp136358_c0_seq1,3458,44.7079,0.52261286,48,135,,7.00E-45,Q8TEP8,Centrosomal protein of 192 kDa (Cep192),Centrosomal protein of 192 kDa (Cep192),GO:0000086; GO:0005814; GO:0005813; GO:0051298; GO:0005829; GO:0010923; GO:0019902; GO:0051225,G2/M transition of mitotic cell cycle; centriole; centrosome; centrosome duplication; cytosol; negative regulation of phosphatase activity; phosphatase binding; spindle assembly,,,,,,,,,,CE192_HUMAN,Homo sapiens (Human),centrosome duplication [GO:0051298]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of phosphatase activity [GO:0010923]; spindle assembly [GO:0051225] comp136363_c0_seq2,2855,36.3923,0.32432436,8,27,,,,,,,,,6.00E-25,CHOYP_TVAG_193760.1.4,,,,,,,,, comp136364_c0_seq1,2023,40.5339,0.53844121,153,386,,1.00E-24,Q8N7Q3,Zinc finger protein 676,Zinc finger protein 676,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;PF13465;,,,,,,,,,ZN676_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136369_c0_seq1,2648,45.8082,0.60494259,10,5,,2.00E-23,Q03427,Lamin-C (pG-IF),Lamin-C (pG-IF),GO:0006325; GO:0006342; GO:0005638; GO:0060415; GO:0031081; GO:0030833; GO:0070732; GO:0005198; GO:0035989,chromatin organization; chromatin silencing; lamin filament; muscle tissue morphogenesis; nuclear pore distribution; regulation of actin filament polymerization; spindle envelope; structural molecule activity; tendon development,PF00038;PF00932;,,,,,,,,,LAMC_DROME,Drosophila melanogaster (Fruit fly),chromatin organization [GO:0006325]; chromatin silencing [GO:0006342]; muscle tissue morphogenesis [GO:0060415]; nuclear pore distribution [GO:0031081]; regulation of actin filament polymerization [GO:0030833]; tendon development [GO:0035989] comp136369_c1_seq2,1680,45.7738,0.58000832,101,58,,5.00E-40,Q4R899,Intermediate filament tail domain-containing protein 1,Lamin tail domain-containing protein 1 (Intermediate filament tail domain-containing protein 1),GO:0005882; GO:0005198,intermediate filament; structural molecule activity,PF00932;,2.00E-77,CHOYP_LOC100378619.1.2,,,,,,,ILFT1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp136370_c0_seq4,260,39.2308,0.5113712,22,13,,2.00E-07,Q9NZV5,Selenoprotein N (SelN),Selenoprotein N (SelN),GO:0005509; GO:0005789; GO:0005576,calcium ion binding; endoplasmic reticulum membrane; extracellular region,,,,,,,,,,SELN_HUMAN,Homo sapiens (Human),calcium ion homeostasis [GO:0055074]; cellular response to caffeine [GO:0071313]; cellular response to oxidative stress [GO:0034599]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; multicellular organismal response to stress [GO:0033555]; positive regulation of response to oxidative stress [GO:1902884]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; respiratory system process [GO:0003016]; response to muscle activity involved in regulation of muscle adaptation [GO:0014873]; skeletal muscle fiber development [GO:0048741]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle tissue regeneration [GO:0043403] comp136371_c0_seq1,965,41.658,0.48053776,57,232,,2.00E-70,O95243,Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding endonuclease 1) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase),Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding endonuclease 1) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase),GO:0031572; GO:0000785; GO:0005737; GO:0045008; GO:0004520; GO:0008630; GO:0005654; GO:0008263; GO:0009314; GO:0003696,G2 DNA damage checkpoint; chromatin; cytoplasm; depyrimidination; endodeoxyribonuclease activity; intrinsic apoptotic signaling pathway in response to DNA damage; nucleoplasm; pyrimidine-specific mismatch base pair DNA N-glycosylase activity; response to radiation; satellite DNA binding,PF01429;,7.00E-50,CHOYP_BRAFLDRAFT_119982.1.1,,,,,,,MBD4_HUMAN,Homo sapiens (Human),depyrimidination [GO:0045008]; DNA repair [GO:0006281]; response to estradiol [GO:0032355]; response to radiation [GO:0009314] comp136371_c1_seq1,2033,37.7767,0.37804809,0,24,,7.00E-18,Q9Z2D6,Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2),Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2),GO:0003677; GO:0008344; GO:0001662; GO:0032048; GO:0050432; GO:0021549; GO:0003682; GO:0006342; GO:0005829; GO:0016358; GO:0010385; GO:0009790; GO:0008211; GO:0006541; GO:0000792; GO:0016573; GO:0016571; GO:0006020; GO:0007616; GO:0060291; GO:0003729; GO:0008327; GO:0006122; GO:0035067; GO:0031061; GO:0043524; GO:0001976; GO:0042551; GO:0005634; GO:0009405; GO:0046470; GO:0008284; GO:0051965; GO:0045893; GO:0009791; GO:0019230; GO:0008104; GO:0060079; GO:0006349; GO:0002087; GO:0006355; GO:0007585; GO:0001666; GO:0019233; GO:0003700; GO:0035197; GO:0035176; GO:0001964; GO:0007416; GO:0006351; GO:0021591; GO:0008542,"DNA binding; adult locomotory behavior; behavioral fear response; cardiolipin metabolic process; catecholamine secretion; cerebellum development; chromatin binding; chromatin silencing; cytosol; dendrite development; double-stranded methylated DNA binding; embryo development; glucocorticoid metabolic process; glutamine metabolic process; heterochromatin; histone acetylation; histone methylation; inositol metabolic process; long-term memory; long-term synaptic potentiation; mRNA binding; methyl-CpG binding; mitochondrial electron transport, ubiquinol to cytochrome c; negative regulation of histone acetylation; negative regulation of histone methylation; negative regulation of neuron apoptotic process; neurological system process involved in regulation of systemic arterial blood pressure; neuron maturation; nucleus; pathogenesis; phosphatidylcholine metabolic process; positive regulation of cell proliferation; positive regulation of synapse assembly; positive regulation of transcription, DNA-dependent; post-embryonic development; proprioception; protein localization; regulation of excitatory postsynaptic membrane potential; regulation of gene expression by genetic imprinting; regulation of respiratory gaseous exchange by neurological system process; regulation of transcription, DNA-dependent; respiratory gaseous exchange; response to hypoxia; sensory perception of pain; sequence-specific DNA binding transcription factor activity; siRNA binding; social behavior; startle response; synapse assembly; transcription, DNA-dependent; ventricular system development; visual learning",PF01429;,,,,,,,,,MECP2_MOUSE,Mus musculus (Mouse),"adult locomotory behavior [GO:0008344]; behavioral fear response [GO:0001662]; brain development [GO:0007420]; cardiolipin metabolic process [GO:0032048]; catecholamine secretion [GO:0050432]; cellular biogenic amine metabolic process [GO:0006576]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chromatin silencing [GO:0006342]; dendrite development [GO:0016358]; excitatory postsynaptic potential [GO:0060079]; glucocorticoid metabolic process [GO:0008211]; glutamine metabolic process [GO:0006541]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone methylation [GO:0016571]; inositol metabolic process [GO:0006020]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; multicellular organismal response to stress [GO:0033555]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone methylation [GO:0031061]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurological system process involved in regulation of systemic arterial blood pressure [GO:0001976]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; pathogenesis [GO:0009405]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse assembly [GO:0051965]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; proprioception [GO:0019230]; protein localization [GO:0008104]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of gene expression, epigenetic [GO:0040029]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; respiratory gaseous exchange [GO:0007585]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventricular system development [GO:0021591]; visual learning [GO:0008542]" comp136371_c1_seq3,2100,37.6667,0.39452762,2,19,,1.00E-17,P51608,Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2),Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2),GO:0008344; GO:0001662; GO:0032048; GO:0050432; GO:0021549; GO:0003682; GO:0006342; GO:0005829; GO:0016358; GO:0010385; GO:0009790; GO:0008211; GO:0006541; GO:0000792; GO:0016573; GO:0016571; GO:0006020; GO:0007616; GO:0060291; GO:0003729; GO:0008327; GO:0006122; GO:0035067; GO:0031061; GO:0043524; GO:0000122; GO:0001976; GO:0042551; GO:0005634; GO:0009405; GO:0046470; GO:0008284; GO:0051965; GO:0045893; GO:0009791; GO:0019230; GO:0008104; GO:0060079; GO:0006349; GO:0002087; GO:0007585; GO:0001666; GO:0019233; GO:0003700; GO:0035197; GO:0035176; GO:0001964; GO:0007416; GO:0003714; GO:0006351; GO:0021591; GO:0008542,"adult locomotory behavior; behavioral fear response; cardiolipin metabolic process; catecholamine secretion; cerebellum development; chromatin binding; chromatin silencing; cytosol; dendrite development; double-stranded methylated DNA binding; embryo development; glucocorticoid metabolic process; glutamine metabolic process; heterochromatin; histone acetylation; histone methylation; inositol metabolic process; long-term memory; long-term synaptic potentiation; mRNA binding; methyl-CpG binding; mitochondrial electron transport, ubiquinol to cytochrome c; negative regulation of histone acetylation; negative regulation of histone methylation; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; neurological system process involved in regulation of systemic arterial blood pressure; neuron maturation; nucleus; pathogenesis; phosphatidylcholine metabolic process; positive regulation of cell proliferation; positive regulation of synapse assembly; positive regulation of transcription, DNA-dependent; post-embryonic development; proprioception; protein localization; regulation of excitatory postsynaptic membrane potential; regulation of gene expression by genetic imprinting; regulation of respiratory gaseous exchange by neurological system process; respiratory gaseous exchange; response to hypoxia; sensory perception of pain; sequence-specific DNA binding transcription factor activity; siRNA binding; social behavior; startle response; synapse assembly; transcription corepressor activity; transcription, DNA-dependent; ventricular system development; visual learning",PF01429;,,,,,,,,,MECP2_HUMAN,Homo sapiens (Human),"adult locomotory behavior [GO:0008344]; behavioral fear response [GO:0001662]; cardiolipin metabolic process [GO:0032048]; catecholamine secretion [GO:0050432]; cerebellum development [GO:0021549]; chromatin silencing [GO:0006342]; dendrite development [GO:0016358]; excitatory postsynaptic potential [GO:0060079]; glucocorticoid metabolic process [GO:0008211]; glutamine metabolic process [GO:0006541]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone methylation [GO:0016571]; inositol metabolic process [GO:0006020]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone methylation [GO:0031061]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurological system process involved in regulation of systemic arterial blood pressure [GO:0001976]; neuron maturation [GO:0042551]; pathogenesis [GO:0009405]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse assembly [GO:0051965]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; proprioception [GO:0019230]; protein localization [GO:0008104]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; respiratory gaseous exchange [GO:0007585]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventricular system development [GO:0021591]; visual learning [GO:0008542]" comp136372_c0_seq1,935,42.4599,0.36494115,0,0,,,,,,,,,2.00E-56,CHOYP_LOC100376892.1.1,,,,,,,,, comp136372_c0_seq3,1144,41.521,0.35706451,0,7,,2.00E-155,Q6GV29,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1) (EC 2.4.1.-)","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1) (EC 2.4.1.-)",GO:0016757,"transferase activity, transferring glycosyl groups",PF00535;,,,,,,,,,B3GNL_RAT,Rattus norvegicus (Rat), comp136372_c0_seq5,323,39.0093,0.52826593,4,0,,3.00E-30,Q6GV29,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1) (EC 2.4.1.-)","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1) (EC 2.4.1.-)",GO:0016757,"transferase activity, transferring glycosyl groups",PF00535;,,,,,,,,,B3GNL_RAT,Rattus norvegicus (Rat), comp136380_c0_seq1,1349,36.1008,0.34229228,47,260,,2.00E-41,Q2KHY5,Fanconi anemia-associated protein of 24 kDa,Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa),GO:0003677; GO:0006281; GO:0043240,DNA binding; DNA repair; Fanconi anaemia nuclear complex,,,,,,,,,,FAP24_BOVIN,Bos taurus (Bovine),DNA repair [GO:0006281] comp136380_c0_seq2,935,33.9037,0.30132831,0,5,,1.00E-14,Q2KHY5,Fanconi anemia-associated protein of 24 kDa,Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa),GO:0003677; GO:0006281; GO:0043240,DNA binding; DNA repair; Fanconi anaemia nuclear complex,,,,,,,,,,FAP24_BOVIN,Bos taurus (Bovine),DNA repair [GO:0006281] comp136382_c1_seq1,1033,44.2401,0.8128315,104,0,,2.00E-06,Q4ZHR9,Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit),Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit),GO:0005525; GO:0005737; GO:0004383; GO:0020037; GO:0035556; GO:0046872,GTP binding; cytoplasm; guanylate cyclase activity; heme binding; intracellular signal transduction; metal ion binding,PF00211;PF07700;PF07701;,,,,,,,,,GCYB1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; signal transduction [GO:0007165] comp136385_c0_seq1,1221,36.1998,0.8677533,14,82,,4.00E-65,Q5SWK7,RING finger protein 145,RING finger protein 145,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF13705;PF13639;,2.00E-44,CHOYP_RN145.1.1,,,,,,,RN145_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp136385_c0_seq2,1253,36.3128,0.84204343,26,154,,1.00E-61,Q5BIY5,RING finger protein 145,RING finger protein 145,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF13705;PF13639;,,,,,,,,,RN145_XENLA,Xenopus laevis (African clawed frog), comp136386_c1_seq2,1112,44.0647,1.13138121,0,0,,3.00E-33,P69526,Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3],Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3],GO:0005887; GO:0006508; GO:0004252,integral to plasma membrane; proteolysis; serine-type endopeptidase activity,PF00057;PF00089;,,,,,,,,,TMPS9_RAT,Rattus norvegicus (Rat), comp136386_c1_seq7,1245,44.0161,1.07969461,0,43,,1.00E-37,Q2KJ63,Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],GO:0007596; GO:0005576; GO:0042730; GO:0006954; GO:0006508; GO:0004252,blood coagulation; extracellular region; fibrinolysis; inflammatory response; proteolysis; serine-type endopeptidase activity,PF00024;PF14295;PF00089;,,,,,,,,,KLKB1_BOVIN,Bos taurus (Bovine),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919] comp136390_c0_seq2,1224,46.0784,0.41761392,47,245,,5.00E-164,Q2HJH1,Aspartyl aminopeptidase (EC 3.4.11.21),Aspartyl aminopeptidase (EC 3.4.11.21),GO:0004177; GO:0005737; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; metallopeptidase activity; proteolysis; zinc ion binding,PF02127;,5.00E-110,CHOYP_BRAFLDRAFT_69005.1.1,,,,,,,DNPEP_BOVIN,Bos taurus (Bovine),peptide metabolic process [GO:0006518] comp136391_c0_seq1,1777,32.3016,0.53996616,7277,44048,,2.00E-43,O42993,Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (FK506-binding protein) (FKBP),Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (FK506-binding protein) (FKBP),GO:0000747; GO:0005829; GO:0005634; GO:0003755; GO:0006457; GO:0000413,conjugation with cellular fusion; cytosol; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00254;,3.00E-26,CHOYP_FKBP1AA.1.1,5.00E-53,ruditapes2_lrc3545,,,,,FKBP_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chaperone-mediated protein folding [GO:0061077]; conjugation with cellular fusion [GO:0000747] comp136394_c0_seq1,906,33.7748,0.23538091,24,85,,,,,,,,,2.00E-11,CHOYP_contig_037355,,,,,,,,, comp136394_c1_seq3,1512,35.119,0.49607993,7,44,,2.00E-15,Q9DC40,Telomere length regulation protein TEL2 homolog,Telomere length regulation protein TEL2 homolog,GO:0031931; GO:0031932; GO:0000781; GO:0005737; GO:0016020; GO:0005634; GO:0032403; GO:0032947; GO:0032006,"TORC1 complex; TORC2 complex; chromosome, telomeric region; cytoplasm; membrane; nucleus; protein complex binding; protein complex scaffold; regulation of TOR signaling cascade",PF10193;,,,,,,,,,TELO2_MOUSE,Mus musculus (Mouse),positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006] comp136394_c8_seq2,1532,40.47,0.4796873,19,37,,1.00E-45,Q921Y4,Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),GO:0016021; GO:0006810,integral to membrane; transport,PF05631;,2.00E-110,CHOYP_LOC100181613.1.1,,,,,,,MFSD5_MOUSE,Mus musculus (Mouse), comp136397_c0_seq1,2374,39.6377,0.45585421,154,743,,0,Q5BJP6,"Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)","Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)",GO:0005525; GO:0003924; GO:0032543; GO:0005739; GO:0032790,GTP binding; GTPase activity; mitochondrial translation; mitochondrion; ribosome disassembly,PF00679;PF14492;PF03764;PF03144;,,,,,,,,,RRF2M_RAT,Rattus norvegicus (Rat),mitochondrial translation [GO:0032543]; ribosome disassembly [GO:0032790] comp136397_c0_seq2,1556,38.3033,0.52200022,8,65,,3.00E-106,Q7Q3I6,"Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)","Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)",GO:0005525; GO:0003924; GO:0032543; GO:0005739; GO:0032790,GTP binding; GTPase activity; mitochondrial translation; mitochondrion; ribosome disassembly,PF00679;PF14492;,3.00E-50,CHOYP_GFM2.1.1,,,,,,,RRF2M_ANOGA,Anopheles gambiae (African malaria mosquito),mitochondrial translation [GO:0032543]; ribosome disassembly [GO:0032790] comp1363_c0_seq1,228,61.4035,1.3085966,0,0,,2.00E-15,Q7D628,Uncharacterized protein Rv3129/MT3215,,GO:0010181; GO:0016491,FMN binding; oxidoreductase activity,,,,,,,,,,Y3129_MYCTU,, comp136400_c0_seq4,1895,39.6306,0.39367654,11,15,,1.00E-109,A7MBP4,Intraflagellar transport protein 46 homolog,Intraflagellar transport protein 46 homolog,GO:0005929; GO:0005737; GO:0048264; GO:0042073; GO:0005932,cilium; cytoplasm; determination of ventral identity; intraflagellar transport; microtubule basal body,PF12317;,4.00E-151,CHOYP_LOC590756.5.6,,,,,,,IFT46_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of ventral identity [GO:0048264]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; retina development in camera-type eye [GO:0060041] comp136400_c0_seq5,2100,40.2381,0.4145527,12,47,,,,,,,,,3.00E-141,CHOYP_LOC590756.4.6,,,,,,,,, comp136404_c0_seq2,1052,34.6958,0.60073919,217,740,,,,,,,,,2.00E-37,CHOYP_UBL5.4.5,,,,,,,,, comp136404_c0_seq3,1070,35.2336,0.60304107,174,1081,,2.00E-35,Q9V998,Ubiquitin-like protein 5,Ubiquitin-like protein 5,GO:0005737; GO:0022008,cytoplasm; neurogenesis,PF14560;,2.00E-37,CHOYP_UBL5.5.5,7.00E-29,ruditapes_c661,,,,,UBL5_DROME,Drosophila melanogaster (Fruit fly),"cellular protein modification process [GO:0006464]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; positive regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034126]" comp136405_c0_seq1,748,44.5187,0.30091361,50,149,,5.00E-28,A6H694,Leucine-rich repeat-containing protein 63,Leucine-rich repeat-containing protein 63,,,PF13855;,,,,,,,,,LRC63_MOUSE,Mus musculus (Mouse), comp136405_c0_seq2,1441,41.7765,0.41458796,162,131,,3.00E-23,Q05C16,Leucine-rich repeat-containing protein 63,Leucine-rich repeat-containing protein 63,,,PF13855;,1.00E-55,CHOYP_LOC757199.1.1,,,,,,,LRC63_HUMAN,Homo sapiens (Human), comp136406_c2_seq1,1880,38.1383,0.46080366,19,44,,2.00E-93,Q9D6K9,Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4),Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4),GO:0046513; GO:0005783; GO:0005789; GO:0016021; GO:0031965; GO:0043565; GO:0003700; GO:0050291,ceramide biosynthetic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sphingosine N-acyltransferase activity,PF00046;PF03798;,,,,,,,,,CERS5_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148] comp136406_c2_seq5,1711,37.931,0.46519949,0,0,,5.00E-94,Q9D6K9,Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4),Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4),GO:0046513; GO:0005783; GO:0005789; GO:0016021; GO:0031965; GO:0043565; GO:0003700; GO:0050291,ceramide biosynthetic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sphingosine N-acyltransferase activity,PF00046;PF03798;,,,,,,,,,CERS5_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148] comp136407_c0_seq1,1014,50.6903,0.5536369,106,15,,,,,,,,,4.00E-28,CHOYP_BRAFLDRAFT_104092.9.11,2.00E-29,ruditapes_c19927,,,,,,, comp136407_c1_seq1,372,45.1613,0.75072423,16,5,,,,,,,,,2.00E-64,CHOYP_LOC588428.5.5,,,,,,,,, comp136407_c3_seq1,922,48.8069,0.64320633,44,8,,,,,,,,,1.00E-26,CHOYP_BRAFLDRAFT_104092.8.11,,,,,,,,, comp136409_c0_seq3,1401,36.6881,0.23765287,56,218,,2.00E-61,P63140,Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (CCAAT-binding transcription factor subunit A) (CBF-A) (Nuclear transcription factor Y subunit B) (NF-YB),Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (CCAAT-binding transcription factor subunit B) (CBF-B) (Nuclear transcription factor Y subunit B) (NF-YB),GO:0016602; GO:0006355; GO:0043565; GO:0006351,"CCAAT-binding factor complex; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF00808;,2.00E-71,CHOYP_NFYB.2.2,,,,,,,NFYB_RAT,Rattus norvegicus (Rat),"positive regulation of transcription, DNA-templated [GO:0045893]; transcription from RNA polymerase II promoter [GO:0006366]" comp136412_c0_seq5,741,39.4062,1.22200486,0,0,,5.00E-19,Q9GPR2,Rho-related protein racI,Rho-related protein racI,GO:0005525; GO:0005622; GO:0005886; GO:0007264,GTP binding; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RACI_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp136412_c0_seq7,656,42.378,1.25862361,6,23,,1.00E-36,Q05062,Cell division control protein 42 homolog (CDC42Ce),Cell division control protein 42 homolog (CDC42Ce),GO:0005525; GO:0003924; GO:0005938; GO:0051301; GO:0009986; GO:0005813; GO:0000132; GO:0016021; GO:0048471; GO:0005886; GO:0055037; GO:0032970; GO:0007264,GTP binding; GTPase activity; cell cortex; cell division; cell surface; centrosome; establishment of mitotic spindle orientation; integral to membrane; perinuclear region of cytoplasm; plasma membrane; recycling endosome; regulation of actin filament-based process; small GTPase mediated signal transduction,PF00071;,,,,,,,,,CDC42_CAEEL,Caenorhabditis elegans,cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin filament-based process [GO:0032970]; small GTPase mediated signal transduction [GO:0007264] comp136413_c1_seq1,384,39.5833,0.88506347,12,7,,,,,,,,,5.00E-15,CHOYP_LOC100893228.1.5,,,,,,,,, comp136413_c2_seq1,1295,34.2085,1.03349344,118,164,,,,,,,,,,,6.00E-18,ruditapes2_c1688,,,,,,, comp136417_c1_seq3,538,30.6691,0.24012557,38,120,,,,,,,,,4.00E-18,CHOYP_contig_040751,,,,,,,,, comp136417_c1_seq6,526,30.9886,0.32007404,0,0,,,,,,,,,6.00E-16,CHOYP_LOC575748.3.4,,,,,,,,, comp136417_c1_seq7,1089,33.9761,0.79769395,0,0,,,,,,,,,,,5.00E-12,ruditapes_c29520,,,,,,, comp136417_c1_seq8,1100,33.7273,0.80089103,0,0,,,,,,,,,1.00E-16,CHOYP_BRAFLDRAFT_88223.6.22,,,,,,,,, comp136418_c1_seq10,2592,40.4321,0.74337329,0,0,,0,Q8BTH8,Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1),Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1),GO:0005524; GO:0016055; GO:0005737; GO:0000287; GO:0042277; GO:0046777; GO:0004674,ATP binding; Wnt receptor signaling pathway; cytoplasm; magnesium ion binding; peptide binding; protein autophosphorylation; protein serine/threonine kinase activity,PF12605;PF00069;,,,,,,,,,KC1G1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055] comp136418_c1_seq4,1936,43.4917,0.71502418,0,0,,0,Q8BTH8,Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1),Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1),GO:0005524; GO:0016055; GO:0005737; GO:0000287; GO:0042277; GO:0046777; GO:0004674,ATP binding; Wnt receptor signaling pathway; cytoplasm; magnesium ion binding; peptide binding; protein autophosphorylation; protein serine/threonine kinase activity,PF12605;PF00069;,0,CHOYP_KC1G3.1.2,,,,,,,KC1G1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055] comp136418_c1_seq5,2484,39.4928,0.73942848,6,5,,0,Q8C4X2,Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1),Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1),GO:0005524; GO:0016055; GO:0005737; GO:0004674,ATP binding; Wnt receptor signaling pathway; cytoplasm; protein serine/threonine kinase activity,PF12605;PF00069;,,,0,ruditapes_c989,,,,,KC1G3_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055] comp136418_c1_seq7,1511,43.2826,0.68659683,0,0,,0,Q62761,Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1),Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1),GO:0005524; GO:0016055; GO:0005737; GO:0001948; GO:0000287; GO:0042277; GO:0051219; GO:0046777; GO:0004674,ATP binding; Wnt receptor signaling pathway; cytoplasm; glycoprotein binding; magnesium ion binding; peptide binding; phosphoprotein binding; protein autophosphorylation; protein serine/threonine kinase activity,PF12605;PF00069;,0,CHOYP_KC1G3.1.2,,,,,,,KC1G1_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055] comp136418_c1_seq8,1828,42.3961,0.71032001,0,0,,0,P78368,Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1),Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1),GO:0005524; GO:0016055; GO:0005829; GO:0000287; GO:0042277; GO:0046777; GO:0004674; GO:0007165; GO:0044281; GO:0030148,ATP binding; Wnt receptor signaling pathway; cytosol; magnesium ion binding; peptide binding; protein autophosphorylation; protein serine/threonine kinase activity; signal transduction; small molecule metabolic process; sphingolipid biosynthetic process,PF12605;PF00069;,0,CHOYP_KC1G3.2.2,3.00E-24,ruditapes_c16356,,,,,KC1G2_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]; Wnt signaling pathway [GO:0016055] comp136419_c0_seq1,1292,40.2477,0.40205248,12,35,,1.00E-34,Q6DEW4,Transcriptional adapter 1 (Transcriptional adapter 1-like protein),Transcriptional adapter 1 (Transcriptional adapter 1-like protein),GO:0070461; GO:0006355; GO:0006351,"SAGA-type complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12767;,,,,,,,,,TADA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136419_c0_seq2,1379,40.8267,0.36604794,40,57,,6.00E-64,Q5RDB9,Transcriptional adapter 1 (Transcriptional adapter 1-like protein),Transcriptional adapter 1 (Transcriptional adapter 1-like protein),GO:0070461; GO:0006355; GO:0006351,"SAGA-type complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12767;,3.00E-18,CHOYP_LOC100374829.1.1,,,,,,,TADA1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136420_c0_seq1,1531,43.501,0.32805764,69,405,,7.00E-84,Q9NUP7,tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76),tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76),GO:0046872; GO:0008168; GO:0008033,metal ion binding; methyltransferase activity; tRNA processing,PF05206;PF11722;PF05253;,,,,,,,,,TRM13_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp136422_c0_seq1,1260,37.7778,0.35624636,4,12,,2.00E-77,Q5R9L6,Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36),Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36),GO:0070531; GO:0070552; GO:0031572; GO:0006302; GO:0070537; GO:0046872; GO:0008237; GO:0031593; GO:0045739; GO:0006508; GO:0010212; GO:0004221; GO:0004843,BRCA1-A complex; BRISC complex; G2 DNA damage checkpoint; double-strand break repair; histone H2A K63-linked deubiquitination; metal ion binding; metallopeptidase activity; polyubiquitin binding; positive regulation of DNA repair; proteolysis; response to ionizing radiation; ubiquitin thiolesterase activity; ubiquitin-specific protease activity,PF01398;,3.00E-56,CHOYP_BRCC3.1.1,,,,,,,BRCC3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell division [GO:0051301]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] comp136422_c0_seq2,1272,37.9717,0.34924576,8,43,,1.00E-110,B5X8M4,Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36),Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36),GO:0070531; GO:0070552; GO:0031572; GO:0006302; GO:0070537; GO:0046872; GO:0008237; GO:0031593; GO:0045739; GO:0006508; GO:0010212; GO:0004221; GO:0004843,BRCA1-A complex; BRISC complex; G2 DNA damage checkpoint; double-strand break repair; histone H2A K63-linked deubiquitination; metal ion binding; metallopeptidase activity; polyubiquitin binding; positive regulation of DNA repair; proteolysis; response to ionizing radiation; ubiquitin thiolesterase activity; ubiquitin-specific protease activity,PF01398;,,,,,,,,,BRCC3_SALSA,Salmo salar (Atlantic salmon),cell division [GO:0051301]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] comp136430_c0_seq1,1893,39.9894,0.670413,453,1643,,1.00E-163,Q5NVI9,DnaJ homolog subfamily A member 1,DnaJ homolog subfamily A member 1,GO:0005524; GO:0016020; GO:0046872; GO:0006457; GO:0009408,ATP binding; membrane; metal ion binding; protein folding; response to heat,PF00226;PF01556;PF00684;,3.00E-133,CHOYP_LOC100374573.1.1,,,,,,,DNJA1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408] comp136433_c0_seq1,2856,37.0448,0.84745343,32,88,,7.00E-58,A2VDL4,Neutral amino acid transporter A (SATT) (Solute carrier family 1 member 4),Neutral amino acid transporter A (SATT) (Solute carrier family 1 member 4),GO:0015180; GO:0015184; GO:0034590; GO:0015193; GO:0015194; GO:0015195; GO:0005254; GO:0050890; GO:0016021; GO:0042470; GO:0017153,L-alanine transmembrane transporter activity; L-cystine transmembrane transporter activity; L-hydroxyproline transmembrane transporter activity; L-proline transmembrane transporter activity; L-serine transmembrane transporter activity; L-threonine transmembrane transporter activity; chloride channel activity; cognition; integral to membrane; melanosome; sodium:dicarboxylate symporter activity,PF00375;,,,,,,,,,SATT_BOVIN,Bos taurus (Bovine),cognition [GO:0050890]; mitophagy in response to mitochondrial depolarization [GO:0098779] comp136433_c0_seq4,569,35.5009,1.01213689,0,0,,,,,,,,,,,3.00E-11,ruditapes2_c2711,,,,,,, comp136434_c0_seq1,3677,34.811,0.55937247,15,0,,5.00E-104,Q8CDN6,Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein),Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein),GO:0045454; GO:0005737; GO:0006662; GO:0005634; GO:0000502; GO:0015035,cell redox homeostasis; cytoplasm; glycerol ether metabolic process; nucleus; proteasome complex; protein disulfide oxidoreductase activity,PF06201;PF00085;,8.00E-69,CHOYP_LOC100893535.1.1,,,,,,,TXNL1_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103] comp136434_c0_seq3,3694,34.8944,0.50925594,159,367,,8.00E-07,Q942L2,Protein disulfide isomerase-like 2-2 (OsPDIL2-2) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-2) (OsPDIL4-2),Protein disulfide isomerase-like 2-2 (OsPDIL2-2) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-2) (OsPDIL4-2),GO:0045454; GO:0005783; GO:0005576; GO:0006662; GO:0003756; GO:0015035; GO:0006457,cell redox homeostasis; endoplasmic reticulum; extracellular region; glycerol ether metabolic process; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding,PF07749;PF00085;,3.00E-73,CHOYP_LOC100893535.1.1,1.00E-158,ruditapes2_c505,,,,,PDI22_ORYSJ,Oryza sativa subsp. japonica (Rice),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp136434_c0_seq4,3691,34.9228,0.55408066,93,410,,5.00E-104,Q8CDN6,Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein),Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein),GO:0045454; GO:0005737; GO:0006662; GO:0005634; GO:0000502; GO:0015035,cell redox homeostasis; cytoplasm; glycerol ether metabolic process; nucleus; proteasome complex; protein disulfide oxidoreductase activity,PF06201;PF00085;,,,,,,,,,TXNL1_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103] comp136434_c0_seq6,3708,34.9784,0.51383465,24,17,,5.00E-104,Q8CDN6,Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein),Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein),GO:0045454; GO:0005737; GO:0006662; GO:0005634; GO:0000502; GO:0015035,cell redox homeostasis; cytoplasm; glycerol ether metabolic process; nucleus; proteasome complex; protein disulfide oxidoreductase activity,PF06201;PF00085;,8.00E-69,CHOYP_LOC100893535.1.1,6.00E-36,ruditapes_c4101,,,,,TXNL1_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103] comp136436_c0_seq1,1475,40.7458,0.46212702,152,123,,7.00E-68,Q5RBJ7,Transmembrane 6 superfamily member 1,Transmembrane 6 superfamily member 1,GO:0016021,integral to membrane,,,,,,,,,,TM6S1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp136437_c0_seq1,2718,39.5879,0.47801893,35,0,,1.00E-166,P93107,Flagellar WD repeat-containing protein Pf20,Flagellar WD repeat-containing protein Pf20,GO:0005929,cilium,PF00400;,,,,,,,,,PF20_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii), comp136437_c0_seq2,2730,39.5238,0.47729742,24,0,,0,Q8N0X2,Sperm-associated antigen 16 protein (Pf20 protein homolog),Sperm-associated antigen 16 protein (Pf20 protein homolog),GO:0042384; GO:0035085; GO:0005874; GO:0005634; GO:0007283,cilium assembly; cilium axoneme; microtubule; nucleus; spermatogenesis,PF00400;,0,CHOYP_SPAG16.1.1,,,,,,,SPG16_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; cell motility in response to calcium ion [GO:0097231]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; microtubule sliding [GO:0051012]; sperm axoneme assembly [GO:0007288] comp136441_c1_seq1,1547,29.0886,1.34584814,178,200,,,,,,,,,,,7.00E-12,ruditapes_c10242,,,,,,, comp136443_c0_seq1,1490,39.396,0.81674862,29,165,,2.00E-28,Q641X7,F-box only protein 25,F-box only protein 25,GO:0019005; GO:0005634; GO:0016567,SCF ubiquitin ligase complex; nucleus; protein ubiquitination,,,,,,,,,,FBX25_RAT,Rattus norvegicus (Rat),protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp136443_c0_seq2,829,39.4451,0.80745459,14,97,,8.00E-16,Q4R372,F-box only protein 25,F-box only protein 25,GO:0019005; GO:0005634; GO:0016567,SCF ubiquitin ligase complex; nucleus; protein ubiquitination,,,,,,,,,,FBX25_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein ubiquitination [GO:0016567] comp136445_c0_seq1,2944,43.5462,0.75332363,60436,136986,,0,P16641,Taurocyamine kinase (EC 2.7.3.4) (ATP:guanidino kinase Smc74) (ATP:guanidino phosphotransferase) (SmGK),Taurocyamine kinase (EC 2.7.3.4) (ATP:guanidino kinase Smc74) (ATP:guanidino phosphotransferase) (SmGK),GO:0005524; GO:0046872; GO:0016491; GO:0050324,ATP binding; metal ion binding; oxidoreductase activity; taurocyamine kinase activity,PF00217;PF02807;,2.00E-43,CHOYP_KARG.10.11,2.00E-156,ruditapes2_c185,,,,,KTRC_SCHMA,Schistosoma mansoni (Blood fluke), comp136448_c0_seq1,2091,39.5026,0.80952176,6,640,female>male,1.00E-45,P07882,Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase),Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase),GO:0005794; GO:0047372; GO:0004091; GO:0005829; GO:0005615; GO:0043208; GO:0016042; GO:0004622; GO:0045121; GO:0043234; GO:0032403; GO:0050253; GO:0005791; GO:0004771; GO:0004806; GO:0042588,Golgi apparatus; acylglycerol lipase activity; carboxylesterase activity; cytosol; extracellular space; glycosphingolipid binding; lipid catabolic process; lysophospholipase activity; membrane raft; protein complex; protein complex binding; retinyl-palmitate esterase activity; rough endoplasmic reticulum; sterol esterase activity; triglyceride lipase activity; zymogen granule,PF00135;,,,,,,,,,CEL_RAT,Rattus norvegicus (Rat),lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp136449_c0_seq2,1134,41.0053,0.82087817,7,70,,7.00E-16,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp136451_c0_seq1,1472,34.8505,0.5039032,384,2248,,1.00E-15,Q9DC71,"28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)","28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)",GO:0005763; GO:0005739; GO:0031965; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; mitochondrion; nuclear membrane; structural constituent of ribosome; translation,PF00312;,,,4.00E-21,ruditapes2_c1764,,,,,RT15_MOUSE,Mus musculus (Mouse),mitochondrial translation [GO:0032543] comp136453_c0_seq1,1327,40.0904,0.46496591,13,8,,6.00E-74,Q9CWZ7,Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma),Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma),GO:0006886; GO:0016020; GO:0005739; GO:0016192,intracellular protein transport; membrane; mitochondrion; vesicle-mediated transport,,,,,,,,,,SNAG_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; vesicle-mediated transport [GO:0016192] comp136453_c0_seq2,1350,39.8519,0.44415405,31,28,,1.00E-74,Q9CWZ7,Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma),Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma),GO:0006886; GO:0016020; GO:0005739; GO:0016192,intracellular protein transport; membrane; mitochondrion; vesicle-mediated transport,,,,,,,,,,SNAG_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; vesicle-mediated transport [GO:0016192] comp136453_c0_seq3,560,45.1786,0.3950211,0,0,,,,,,,,,3.00E-19,CHOYP_BRAFLDRAFT_285193.1.1,,,,,,,,, comp136462_c0_seq1,1339,40.0299,0.41127255,199,895,,2.00E-140,Q28ID3,Glutaredoxin-3 (Thioredoxin-like protein 2),Glutaredoxin-3 (Thioredoxin-like protein 2),GO:0005938; GO:0045454; GO:0009055; GO:0015035,cell cortex; cell redox homeostasis; electron carrier activity; protein disulfide oxidoreductase activity,PF00462;PF00085;,6.00E-90,CHOYP_GLRX3.1.1,,,,,,,GLRX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell redox homeostasis [GO:0045454] comp136463_c0_seq2,1463,42.7888,0.44847008,5,32,,1.00E-25,Q54P76,Exocyst complex component 4 (Exocyst complex component Sec8),Exocyst complex component 4 (Exocyst complex component Sec8),GO:0000145; GO:0015031; GO:0006904,exocyst; protein transport; vesicle docking involved in exocytosis,PF04048;,0,CHOYP_EXOC4.1.2,2.00E-50,ruditapes_c26947,,,,,EXOC4_DICDI,Dictyostelium discoideum (Slime mold),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp136463_c0_seq3,2090,40.6699,0.48621457,11,24,,5.00E-143,Q62824,Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8),Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8),GO:0055108; GO:0030165; GO:0043198; GO:0030010; GO:0000145; GO:0030426; GO:0044091; GO:0043209; GO:0043025; GO:0048709; GO:0050850; GO:0014069; GO:0032403; GO:0006612; GO:0051223; GO:0007268; GO:0006904; GO:0006903,Golgi to transport vesicle transport; PDZ domain binding; dendritic shaft; establishment of cell polarity; exocyst; growth cone; membrane biogenesis; myelin sheath; neuronal cell body; oligodendrocyte differentiation; positive regulation of calcium-mediated signaling; postsynaptic density; protein complex binding; protein targeting to membrane; regulation of protein transport; synaptic transmission; vesicle docking involved in exocytosis; vesicle targeting,PF04048;,0,CHOYP_EXOC4.1.2,,,,,,,EXOC4_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; establishment of cell polarity [GO:0030010]; Golgi to transport vesicle transport [GO:0055108]; membrane biogenesis [GO:0044091]; oligodendrocyte differentiation [GO:0048709]; positive regulation of calcium-mediated signaling [GO:0050850]; protein targeting to membrane [GO:0006612]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903] comp136464_c3_seq1,1215,44.3621,0.56939854,17,31,,2.00E-125,Q96P47,"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)","Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)",GO:0008060; GO:0005525; GO:0003924; GO:0071944; GO:0034614; GO:0005737; GO:0016020; GO:0005634; GO:0005543; GO:0043547; GO:0043161; GO:0000060; GO:0032312; GO:0007264; GO:0008270,"ARF GTPase activator activity; GTP binding; GTPase activity; cell periphery; cellular response to reactive oxygen species; cytoplasm; membrane; nucleus; phospholipid binding; positive regulation of GTPase activity; proteasomal ubiquitin-dependent protein catabolic process; protein import into nucleus, translocation; regulation of ARF GTPase activity; small GTPase mediated signal transduction; zinc ion binding",PF12796;PF01412;PF00071;,8.00E-158,CHOYP_CEG1A.4.6,,,,,,,AGAP3_HUMAN,Homo sapiens (Human),small GTPase mediated signal transduction [GO:0007264] comp136464_c3_seq2,411,46.7153,0.47685467,0,0,,,,,,,,,9.00E-38,CHOYP_LOC100369235.1.1,,,,,,,,, comp136464_c3_seq3,1608,45.398,0.58749005,62,84,,1.00E-143,Q9NGC3,Centaurin-gamma-1A,Centaurin-gamma-1A,GO:0008060; GO:0005525; GO:0005634; GO:0005543; GO:0032312; GO:0007264; GO:0008270,ARF GTPase activator activity; GTP binding; nucleus; phospholipid binding; regulation of ARF GTPase activity; small GTPase mediated signal transduction; zinc ion binding,PF01412;PF00071;,9.00E-108,CHOYP_CEG1A.5.6,,,,,,,CEG1A_DROME,Drosophila melanogaster (Fruit fly),medium-term memory [GO:0072375]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; small GTPase mediated signal transduction [GO:0007264] comp136464_c3_seq5,675,43.4074,0.50655787,0,0,,3.00E-06,B4KB60,Ras-like protein 1,Ras-like protein 1,GO:0005525; GO:0003924; GO:0016020; GO:0005886; GO:0007264,GTP binding; GTPase activity; membrane; plasma membrane; small GTPase mediated signal transduction,PF00071;,9.00E-85,CHOYP_CEG1A.2.6,4.00E-11,ruditapes_c19285,,,,,RAS1_DROMO,Drosophila mojavensis (Fruit fly),small GTPase mediated signal transduction [GO:0007264] comp136465_c0_seq1,5256,52.93,0.64661918,4395,12702,,8.00E-17,Q5UQ13,Collagen-like protein 2,Collagen-like protein 2,GO:0005581; GO:0019012,collagen; virion,PF01391;,2.00E-15,CHOYP_CO2A1.1.1,2.00E-19,ruditapes_lrc34023,,,,,COLL2_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp136466_c4_seq1,902,42.2395,0.6718388,32,300,,6.00E-54,Q8C8M1,Protein FAM60A (Tera protein),Protein FAM60A (Tera protein),GO:0016580; GO:0030336,Sin3 complex; negative regulation of cell migration,PF15396;,1.00E-46,CHOYP_LOC100371590.1.1,,,,,,,FA60A_MOUSE,Mus musculus (Mouse),negative regulation of cell migration [GO:0030336] comp136468_c0_seq1,2119,49.1741,0.54057309,7,6,,2.00E-134,Q3V096,Ankyrin repeat domain-containing protein 42,Ankyrin repeat domain-containing protein 42,GO:0005634; GO:0051092; GO:1900017,nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production involved in inflammatory response,PF12796;,1.00E-108,CHOYP_LOC576698.1.1,,,,,,,ANR42_MOUSE,Mus musculus (Mouse),positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091] comp136468_c0_seq2,1274,47.9592,0.64466174,0,0,,9.00E-10,Q9NXR5,Ankyrin repeat domain-containing protein 10,Ankyrin repeat domain-containing protein 10,,,PF12796;,,,,,,,,,ANR10_HUMAN,Homo sapiens (Human),regulation of canonical Wnt signaling pathway [GO:0060828] comp136468_c0_seq3,2092,49.1396,0.53995862,5,8,,1.00E-137,Q3V096,Ankyrin repeat domain-containing protein 42,Ankyrin repeat domain-containing protein 42,GO:0005634; GO:0051092; GO:1900017,nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production involved in inflammatory response,PF12796;,2.00E-123,CHOYP_LOC576698.1.1,,,,,,,ANR42_MOUSE,Mus musculus (Mouse),positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091] comp136470_c0_seq1,2155,39.1647,1.22310808,2,923,female>male,1.00E-48,Q03442,Crystallin J1A,Crystallin J1A,GO:0005212,structural constituent of eye lens,PF03747;,,,,,,,,,CRJ1A_TRICY,Tripedalia cystophora (Jellyfish), comp136472_c1_seq1,1339,35.997,0.39647753,62,789,,6.00E-69,Q99470,Stromal cell-derived factor 2 (SDF-2),Stromal cell-derived factor 2 (SDF-2),GO:0004169; GO:0005615; GO:0016020; GO:0006486,dolichyl-phosphate-mannose-protein mannosyltransferase activity; extracellular space; membrane; protein glycosylation,PF02815;,2.00E-89,CHOYP_LOC100562697.1.1,,,,,,,SDF2_HUMAN,Homo sapiens (Human),cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; multicellular organism development [GO:0007275]; protein glycosylation [GO:0006486]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101] comp136473_c0_seq2,968,38.6364,0.58514555,32,89,,,,,,,,,,,2.00E-11,ruditapes_c24988,,,,,,, comp136473_c1_seq1,1500,47.5333,0.57323832,124,141,,2.00E-172,Q0III3,"Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)","Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)",GO:0005868; GO:0005874; GO:0007018; GO:0003774; GO:0006810; GO:0031982,cytoplasmic dynein complex; microtubule; microtubule-based movement; motor activity; transport; vesicle,PF11540;PF00400;,2.00E-161,CHOYP_DC1I2.1.3,,,,,,,DC1I2_BOVIN,Bos taurus (Bovine),microtubule-based movement [GO:0007018]; transport [GO:0006810] comp136475_c0_seq1,1680,38.9286,0.45778883,628,3706,,2.00E-122,P58389,"Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B')","Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B')",GO:0005524; GO:0006200; GO:0005737; GO:0030472; GO:0032515; GO:0035308; GO:0005634; GO:0003755; GO:0032516; GO:0035307; GO:0006457; GO:0042803; GO:0051721; GO:0000159; GO:0008601; GO:0008160,ATP binding; ATP catabolic process; cytoplasm; mitotic spindle organization in nucleus; negative regulation of phosphoprotein phosphatase activity; negative regulation of protein dephosphorylation; nucleus; peptidyl-prolyl cis-trans isomerase activity; positive regulation of phosphoprotein phosphatase activity; positive regulation of protein dephosphorylation; protein folding; protein homodimerization activity; protein phosphatase 2A binding; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; protein tyrosine phosphatase activator activity,PF03095;,2.00E-72,CHOYP_PTPA.1.1,,,,,,,PTPA_MOUSE,Mus musculus (Mouse),mitotic spindle organization in nucleus [GO:0030472]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of phosphoprotein phosphatase activity [GO:0043666] comp136479_c0_seq1,1546,36.2872,0.35760533,7,6,,5.00E-18,Q5BK24,Uncharacterized protein C8orf76 homolog,Uncharacterized protein C8orf76 homolog,,,,,,,,,,,,CH076_RAT,Rattus norvegicus (Rat), comp136480_c0_seq1,1836,43.9542,1.00678019,382,3237,,6.00E-25,Q98SV0,Selenoprotein Pb (zSelPb),Selenoprotein Pb (zSelPb),GO:0005576; GO:0006979; GO:0008430,extracellular region; response to oxidative stress; selenium binding,PF04592;,,,,,,,,,SELPB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136484_c0_seq1,1034,35.6867,0.39845453,0,0,,8.00E-14,Q86XK3,Swi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog),Swi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog),GO:0032798; GO:0000724,Swi5-Sfr1 complex; double-strand break repair via homologous recombination,PF10376;,,,,,,,,,SFR1_HUMAN,Homo sapiens (Human),"cellular response to estrogen stimulus [GO:0071391]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp136485_c0_seq1,476,42.0168,0.24091015,30,18,,2.00E-07,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136486_c0_seq1,1524,37.5984,0.63224024,548,1520,,9.00E-99,Q3MHN0,Proteasome subunit beta type-6 (EC 3.4.25.1),Proteasome subunit beta type-6 (EC 3.4.25.1),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,,,,,,,,,PSB6_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp136486_c0_seq2,1369,38.9335,0.63667123,930,1509,,2.00E-99,Q3MHN0,Proteasome subunit beta type-6 (EC 3.4.25.1),Proteasome subunit beta type-6 (EC 3.4.25.1),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,2.00E-78,CHOYP_LOC100375089.1.1,9.00E-99,ruditapes2_c2305,2.00E-80,AM863722.p.cg.6,8,,PSB6_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp136489_c0_seq1,802,37.5312,0.52557351,0,4,,5.00E-15,Q3UY23,Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1),Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1),GO:0005524; GO:0000287; GO:0004826; GO:0006432; GO:0000049; GO:0008033,ATP binding; magnesium ion binding; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding; tRNA processing,PF10354;PF03147;,,,,,,,,,FDXA1_MOUSE,Mus musculus (Mouse),rRNA base methylation [GO:0070475]; tRNA processing [GO:0008033] comp136490_c0_seq1,3616,37.1405,0.41025591,1469,14500,,1.00E-51,Q6PC91,Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4),Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4),,,PF01849;,4.00E-104,CHOYP_BT3L4.1.1,1.00E-57,ruditapes_c124,,,,,BT3L4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136490_c0_seq2,3652,37.1851,0.43830711,1354,5949,,,,,,,,,9.00E-100,CHOYP_GNPTG.2.2,,,,,,,,, comp136490_c0_seq3,3668,37.132,0.43726013,280,7642,,1.00E-51,Q6PC91,Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4),Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4),,,PF01849;,4.00E-104,CHOYP_BT3L4.1.1,6.00E-138,ruditapes_lrc34458,,,,,BT3L4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136492_c0_seq2,4156,34.4321,0.35239372,0,0,,0,P08059,Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI),Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI),GO:0001525; GO:0005737; GO:0005615; GO:0006094; GO:0004347; GO:0006096,angiogenesis; cytoplasm; extracellular space; gluconeogenesis; glucose-6-phosphate isomerase activity; glycolysis,PF00342;,,,,,,,,,G6PI_PIG,Sus scrofa (Pig),angiogenesis [GO:0001525]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096] comp136492_c0_seq6,4229,34.4526,0.35355667,5,21,,0,P08059,Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI),Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI),GO:0001525; GO:0005737; GO:0005615; GO:0006094; GO:0004347; GO:0006096,angiogenesis; cytoplasm; extracellular space; gluconeogenesis; glucose-6-phosphate isomerase activity; glycolysis,PF00342;,0,CHOYP_LOC100366799.1.2,,,,,,,G6PI_PIG,Sus scrofa (Pig),angiogenesis [GO:0001525]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096] comp136493_c0_seq1,1346,34.9926,0.61755031,3873,900,,5.00E-49,Q60547,Synaptonemal complex protein 3 (SCP-3) (Meiotic chromosome core protein) (Synaptonemal complex protein COR1),Synaptonemal complex protein 3 (SCP-3) (Meiotic chromosome core protein) (Synaptonemal complex protein COR1),GO:0000775; GO:0005634,"chromosome, centromeric region; nucleus",PF04803;,2.00E-52,CHOYP_LOC100083524.1.1,,,,,,,SYCP3_MESAU,Mesocricetus auratus (Golden hamster),cell division [GO:0051301]; meiotic cell cycle [GO:0051321] comp136497_c0_seq1,1466,46.1801,0.34585176,96,35,,,,,,,,,2.00E-72,CHOYP_BRAFLDRAFT_69981.1.1,,,,,,,,, comp136497_c1_seq1,644,40.0621,0.39814911,26,13,,,,,,,,,5.00E-75,CHOYP_BRAFLDRAFT_69981.1.1,,,,,,,,, comp136501_c2_seq1,1058,40.8318,0.36630956,32,77,,2.00E-83,Q3MQ24,Autophagy protein 5,Autophagy protein 5,GO:0006915; GO:0005776; GO:0000045; GO:0001974; GO:0060047; GO:0045087; GO:0043066; GO:0031397; GO:0048840; GO:0043687; GO:0034045; GO:0002739; GO:0042493; GO:0009620; GO:0042311; GO:0055015,apoptotic process; autophagic vacuole; autophagic vacuole assembly; blood vessel remodeling; heart contraction; innate immune response; negative regulation of apoptotic process; negative regulation of protein ubiquitination; otolith development; post-translational protein modification; pre-autophagosomal structure membrane; regulation of cytokine secretion involved in immune response; response to drug; response to fungus; vasodilation; ventricular cardiac muscle cell development,PF04106;,1.00E-33,CHOYP_BRAFLDRAFT_115265.1.1,,,,,,,ATG5_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; C-terminal protein lipidation [GO:0006501]; innate immune response [GO:0045087]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; regulation of cilium assembly [GO:1902017] comp136503_c0_seq1,1191,37.1117,1.14791598,3,377,female>male,1.00E-41,O14792,Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1),Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1),GO:0005796; GO:0008467; GO:0005975; GO:0006024; GO:0016021; GO:0044281; GO:0008146,Golgi lumen; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; carbohydrate metabolic process; glycosaminoglycan biosynthetic process; integral to membrane; small molecule metabolic process; sulfotransferase activity,PF00685;,,,,,,,,,HS3S1_HUMAN,Homo sapiens (Human),glycosaminoglycan biosynthetic process [GO:0006024] comp136504_c0_seq1,912,39.9123,0.72631119,0,0,,7.00E-13,P13595,Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56),Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56),GO:0031225; GO:0030424; GO:0007166; GO:0009897; GO:0030426; GO:0008201; GO:0034109; GO:0016021; GO:0031175; GO:0043025; GO:0050850; GO:0001928,anchored to membrane; axon; cell surface receptor signaling pathway; external side of plasma membrane; growth cone; heparin binding; homotypic cell-cell adhesion; integral to membrane; neuron projection development; neuronal cell body; positive regulation of calcium-mediated signaling; regulation of exocyst assembly,PF00041;PF07679;,,,,,,,,,NCAM1_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; homotypic cell-cell adhesion [GO:0034109]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; regulation of exocyst assembly [GO:0001928]; regulation of synaptic plasticity [GO:0048167] comp136504_c0_seq2,939,40.4686,0.79278154,0,0,,2.00E-47,P16621,Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR),Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR),GO:0045467; GO:0030424; GO:0048675; GO:0007412; GO:0007155; GO:0001700; GO:0005925; GO:0008201; GO:0016021; GO:0005875; GO:0008045; GO:0048477; GO:0008594; GO:0005886; GO:0048841; GO:0008360; GO:0031290; GO:0051124; GO:0005001,R7 cell development; axon; axon extension; axon target recognition; cell adhesion; embryonic development via the syncytial blastoderm; focal adhesion; heparin binding; integral to membrane; microtubule associated complex; motor neuron axon guidance; oogenesis; photoreceptor cell morphogenesis; plasma membrane; regulation of axon extension involved in axon guidance; regulation of cell shape; retinal ganglion cell axon guidance; synaptic growth at neuromuscular junction; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF07679;PF00102;,,,,,,,,,LAR_DROME,Drosophila melanogaster (Fruit fly),axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; embryonic development via the syncytial blastoderm [GO:0001700]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; photoreceptor cell morphogenesis [GO:0008594]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell shape [GO:0008360]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124] comp136504_c0_seq3,1002,40.6188,0.83879462,0,0,,2.00E-43,Q64605,Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma),Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma),GO:0007155; GO:0016021; GO:0004725,cell adhesion; integral to membrane; protein tyrosine phosphatase activity,PF00041;PF07679;PF00102;,,,,,,,,,PTPRS_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp136504_c0_seq4,849,39.6938,0.66500803,0,0,,3.00E-14,P13590,Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1),Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;,,,,,,,,,NCAM1_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167] comp136507_c2_seq1,1775,40.507,0.56865305,121,30,,4.00E-34,Q8N0U4,Protein FAM185A,Protein FAM185A,GO:0005737,cytoplasm,PF13349;,,,,,,,,,F185A_HUMAN,Homo sapiens (Human), comp136508_c2_seq3,3012,44.5219,0.40920187,0,0,,0,Q9NR09,Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),GO:0005794; GO:0006915; GO:0051301; GO:0004869; GO:0005768; GO:0060711; GO:0016020; GO:0005815; GO:0030496; GO:0007067; GO:0043066; GO:2001237; GO:0008284; GO:0006468; GO:0042127; GO:0032465; GO:0000922; GO:0060712; GO:0005802; GO:0004842,Golgi apparatus; apoptotic process; cell division; cysteine-type endopeptidase inhibitor activity; endosome; labyrinthine layer development; membrane; microtubule organizing center; midbody; mitosis; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; positive regulation of cell proliferation; protein phosphorylation; regulation of cell proliferation; regulation of cytokinesis; spindle pole; spongiotrophoblast layer development; trans-Golgi network; ubiquitin-protein ligase activity,PF00653;PF12356;PF00179;,0,CHOYP_BIRC6.1.2,,,,,,,BIRC6_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] comp136508_c2_seq4,3077,44.1664,0.40698405,3,2,,0,Q9NR09,Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),GO:0005794; GO:0006915; GO:0051301; GO:0004869; GO:0005768; GO:0060711; GO:0016020; GO:0005815; GO:0030496; GO:0007067; GO:0043066; GO:2001237; GO:0008284; GO:0006468; GO:0042127; GO:0032465; GO:0000922; GO:0060712; GO:0005802; GO:0004842,Golgi apparatus; apoptotic process; cell division; cysteine-type endopeptidase inhibitor activity; endosome; labyrinthine layer development; membrane; microtubule organizing center; midbody; mitosis; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; positive regulation of cell proliferation; protein phosphorylation; regulation of cell proliferation; regulation of cytokinesis; spindle pole; spongiotrophoblast layer development; trans-Golgi network; ubiquitin-protein ligase activity,PF00653;PF12356;PF00179;,,,,,,,,,BIRC6_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] comp136509_c0_seq1,2037,40.3044,0.98787605,52,193,,1.00E-28,Q9FWW6,Flavin-containing monooxygenase FMO GS-OX-like 1 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 1),Flavin-containing monooxygenase FMO GS-OX-like 1 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 1),GO:0004499; GO:0050661; GO:0050660,"N,N-dimethylaniline monooxygenase activity; NADP binding; flavin adenine dinucleotide binding",PF00743;,,,,,,,,,GSXL1_ARATH,Arabidopsis thaliana (Mouse-ear cress),oxidation-reduction process [GO:0055114] comp136509_c0_seq2,2017,40.2578,0.98805351,0,41,,2.00E-30,Q9FF12,Flavin-containing monooxygenase FMO GS-OX-like 9 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 9),Flavin-containing monooxygenase FMO GS-OX-like 9 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 9),GO:0004499; GO:0050661; GO:0050660,"N,N-dimethylaniline monooxygenase activity; NADP binding; flavin adenine dinucleotide binding",PF00743;,,,,,,,,,GSXL9_ARATH,Arabidopsis thaliana (Mouse-ear cress),oxidation-reduction process [GO:0055114] comp136510_c0_seq1,1106,39.6022,0.5041425,0,0,,7.00E-07,Q9BXK1,Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2),Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2),GO:0003677; GO:0007212; GO:0046872; GO:0005634; GO:0006357; GO:0003700; GO:0006351,"DNA binding; dopamine receptor signaling pathway; metal ion binding; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,KLF16_HUMAN,Homo sapiens (Human),"dopamine receptor signaling pathway [GO:0007212]; transcription, DNA-templated [GO:0006351]" comp136510_c0_seq2,1335,39.4757,0.5524741,0,0,,5.00E-20,Q8BV42,Zinc finger protein 786,Zinc finger protein 786,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;,,,,,,,,,ZN786_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136510_c0_seq3,400,39.75,0.51099396,0,26,,3.00E-17,Q3U133,Zinc finger protein 746,Zinc finger protein 746,GO:0005737; GO:0046872; GO:0045892; GO:0070997; GO:0005634; GO:0010941; GO:0044212; GO:0006351,"cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; neuron death; nucleus; regulation of cell death; transcription regulatory region DNA binding; transcription, DNA-dependent",PF12417;PF01352;PF00096;PF13912;,,,,,,,,,ZN746_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp136510_c0_seq4,1840,38.2609,0.51052149,0,0,,3.00E-25,Q96C55,Zinc finger protein 524,Zinc finger protein 524,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZN524_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136510_c0_seq5,1222,39.5254,0.5409976,0,0,,4.00E-33,Q8K2R5,Zinc finger protein 668,Zinc finger protein 668,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN668_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp136510_c0_seq6,1727,38.2166,0.49816349,0,0,,4.00E-33,Q9NW07,Zinc finger protein 358,Zinc finger protein 358,GO:0003677; GO:0035115; GO:0046872; GO:0021915; GO:0005634; GO:0006355; GO:0019827; GO:0006351,"DNA binding; embryonic forelimb morphogenesis; metal ion binding; neural tube development; nucleus; regulation of transcription, DNA-dependent; stem cell maintenance; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN358_HUMAN,Homo sapiens (Human),"embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]" comp136510_c0_seq9,1611,38.175,0.46724656,0,0,,2.00E-13,Q8CIV7,Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO),Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO),GO:0003677; GO:0001525; GO:0009953; GO:0048557; GO:0060214; GO:0001947; GO:0060347; GO:0060716; GO:0046872; GO:0045746; GO:0008285; GO:0045617; GO:0010944; GO:0045892; GO:0001755; GO:0001842; GO:0005634; GO:0045893; GO:0051726; GO:0010837; GO:0000981; GO:0044212,"DNA binding; angiogenesis; dorsal/ventral pattern formation; embryonic digestive tract morphogenesis; endocardium formation; heart looping; heart trabecula formation; labyrinthine layer blood vessel development; metal ion binding; negative regulation of Notch signaling pathway; negative regulation of cell proliferation; negative regulation of keratinocyte differentiation; negative regulation of transcription by competitive promoter binding; negative regulation of transcription, DNA-dependent; neural crest cell migration; neural fold formation; nucleus; positive regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of keratinocyte proliferation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription regulatory region DNA binding",,,,,,,,,,OVOL2_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; dorsal/ventral pattern formation [GO:0009953]; embryonic digestive tract morphogenesis [GO:0048557]; endocardium formation [GO:0060214]; epidermal cell differentiation [GO:0009913]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of keratinocyte proliferation [GO:0010837]" comp136514_c0_seq3,257,35.7977,1.1020575,13,46,,,,,,,,,,,1.00E-11,ruditapes_c25723,,,,,,, comp136518_c0_seq1,1517,44.7594,0.91389971,0,0,,5.00E-37,Q8BGC3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_MOUSE,Mus musculus (Mouse),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp136518_c0_seq2,1606,44.0847,0.88857848,0,0,,1.00E-27,O95907,Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8),Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8),GO:0007596; GO:0005887; GO:0015129; GO:0050900; GO:0006090; GO:0015355; GO:0015293,blood coagulation; integral to plasma membrane; lactate transmembrane transporter activity; leukocyte migration; pyruvate metabolic process; secondary active monocarboxylate transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT3_HUMAN,Homo sapiens (Human),lactate transport [GO:0015727]; leukocyte migration [GO:0050900]; plasma membrane lactate transport [GO:0035879]; pyruvate metabolic process [GO:0006090] comp136518_c0_seq4,1394,45.2654,0.93152479,0,0,,2.00E-06,Q0K843,Probable sulfoacetate transporter SauU,Probable sulfoacetate transporter SauU,GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,SAUU_CUPNH,Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha),transmembrane transport [GO:0055085] comp136518_c0_seq9,1407,45.2736,0.93594777,0,0,,6.00E-39,Q8BGC3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_MOUSE,Mus musculus (Mouse),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp136525_c0_seq1,2797,37.0754,0.40113187,2031,6246,,0,Q9DE26,RuvB-like 1 (EC 3.6.4.12) (Pontin),RuvB-like 1 (EC 3.6.4.12) (Pontin),GO:0005524; GO:0043141; GO:0032508; GO:0006310; GO:0006281; GO:0071339; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 5'-3' DNA helicase activity; DNA duplex unwinding; DNA recombination; DNA repair; MLL1 complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF06068;,0,CHOYP_RUVB1.1.1,,,,,,,RUVB1_XENLA,Xenopus laevis (African clawed frog),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136526_c0_seq1,1834,38.277,0.48320252,131,714,,4.00E-65,Q5TC84,Opioid growth factor receptor-like protein 1,Opioid growth factor receptor-like protein 1,GO:0016020; GO:0004872,membrane; receptor activity,PF04664;,5.00E-36,CHOYP_OGFRL1.1.1,,,,,,,OGRL1_HUMAN,Homo sapiens (Human), comp136529_c0_seq1,1331,43.5011,0.50943844,0,10,,4.00E-66,Q08DP1,tRNA methyltransferase 10 homolog B (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 3),tRNA methyltransferase 10 homolog B (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 3),GO:0008168,methyltransferase activity,PF01746;,,,,,,,,,TM10B_BOVIN,Bos taurus (Bovine), comp136534_c0_seq1,1967,39.5018,0.96755187,126,994,,7.00E-83,Q9CX98,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_MOUSE,Mus musculus (Mouse), comp136537_c0_seq1,1818,47.0297,0.45792074,0,10,,,,,,,,,,,4.00E-35,ruditapes_c12100,,,,,,, comp136537_c0_seq2,3416,41.0129,0.45603034,85,171,,7.00E-27,Q15643,Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230),Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230),GO:0005794; GO:0005856; GO:0016020; GO:0005634; GO:0000042; GO:0003713; GO:0006366; GO:0003281,Golgi apparatus; cytoskeleton; membrane; nucleus; protein targeting to Golgi; transcription coactivator activity; transcription from RNA polymerase II promoter; ventricular septum development,,1.00E-40,CHOYP_LOC100540539.1.1,,,,,,,TRIPB_HUMAN,Homo sapiens (Human),protein targeting to Golgi [GO:0000042]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281] comp136538_c0_seq5,1036,32.4324,0.40834117,1,0,,,,,,,,,,,2.00E-11,ruditapes_c1831,,,,,,, comp136543_c0_seq2,1019,39.156,0.56925473,26,70,,9.00E-12,Q9DBF7,Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25),Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25),,,PF10197;PF12542;,5.00E-14,CHOYP_LOC577351.1.1,,,,,,,CWC25_MOUSE,Mus musculus (Mouse), comp136545_c0_seq1,2138,36.3424,0.40162019,214,2215,,7.00E-16,Q6VUC1,DPH3 homolog (CSL-type zinc finger-containing protein 2) (Diphtheria toxin and Pseudomonas exotoxin A sensitivity-required protein 1),DPH3 homolog (CSL-type zinc finger-containing protein 2) (Diphtheria toxin and Pseudomonas exotoxin A sensitivity-required protein 1),GO:0005737; GO:0046872; GO:0050709; GO:0005634; GO:0017183; GO:0051099,cytoplasm; metal ion binding; negative regulation of protein secretion; nucleus; peptidyl-diphthamide biosynthetic process from peptidyl-histidine; positive regulation of binding,PF05207;,3.00E-52,CHOYP_LOC100893196.2.2,,,,,,,DPH3_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),negative regulation of protein secretion [GO:0050709]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; positive regulation of binding [GO:0051099] comp136546_c0_seq1,2515,45.4076,0.65839263,0,0,,0,Q8VBV4,F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10),F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10),GO:0005794; GO:0007219; GO:0019005; GO:0031146; GO:0005783; GO:0030324; GO:0005634; GO:0048471; GO:0016567; GO:0003700; GO:0001570,Golgi apparatus; Notch signaling pathway; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; endoplasmic reticulum; lung development; nucleus; perinuclear region of cytoplasm; protein ubiquitination; sequence-specific DNA binding transcription factor activity; vasculogenesis,PF12937;PF00400;,0,CHOYP_FBXW7.1.1,,,,,,,FBXW7_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lung development [GO:0030324]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of mitophagy [GO:1903146]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] comp136546_c0_seq2,2998,45.5971,0.63840951,41,54,,0,Q969H0,F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4),F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4),GO:0005794; GO:0007219; GO:0019005; GO:0031146; GO:0034644; GO:0005783; GO:0055088; GO:0030324; GO:0019048; GO:0032876; GO:0045746; GO:2000639; GO:2000346; GO:0010868; GO:0005730; GO:0005654; GO:0070374; GO:0045741; GO:2000060; GO:0043234; GO:0050821; GO:0016567; GO:0010883; GO:0032880; GO:0006974; GO:0003700; GO:0007062; GO:0001944; GO:0001570,Golgi apparatus; Notch signaling pathway; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular response to UV; endoplasmic reticulum; lipid homeostasis; lung development; modulation by virus of host morphology or physiology; negative regulation of DNA endoreduplication; negative regulation of Notch signaling pathway; negative regulation of SREBP signaling pathway; negative regulation of hepatocyte proliferation; negative regulation of triglyceride biosynthetic process; nucleolus; nucleoplasm; positive regulation of ERK1 and ERK2 cascade; positive regulation of epidermal growth factor-activated receptor activity; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein complex; protein stabilization; protein ubiquitination; regulation of lipid storage; regulation of protein localization; response to DNA damage stimulus; sequence-specific DNA binding transcription factor activity; sister chromatid cohesion; vasculature development; vasculogenesis,PF12937;PF00400;,,,,,2.00E-93,AM868009.p.cg.6,3,,FBXW7_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of lipid storage [GO:0010883]; regulation of mitophagy [GO:1903146]; regulation of protein localization [GO:0032880]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculature development [GO:0001944]; viral process [GO:0016032] comp136548_c1_seq1,710,51.6901,0.53120062,0,0,,6.00E-12,Q803A8,WW domain-containing oxidoreductase (EC 1.1.1.-),WW domain-containing oxidoreductase (EC 1.1.1.-),GO:0016055; GO:0006915; GO:0005737; GO:0005634; GO:0016491,Wnt receptor signaling pathway; apoptotic process; cytoplasm; nucleus; oxidoreductase activity,PF00106;PF00397;,,,,,,,,,WWOX_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; cellular calcium ion homeostasis [GO:0006874]; Wnt signaling pathway [GO:0016055] comp136548_c1_seq2,2200,44.6818,0.47787502,16,0,,2.00E-29,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,0,CHOYP_SUDX.1.1,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp136548_c1_seq4,2034,45.7719,0.50116643,0,0,,0,Q8BZZ3,NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain-containing protein 1),NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain-containing protein 1),GO:0030217; GO:0005737; GO:0030324; GO:0045892; GO:0005634; GO:0005886; GO:0043161; GO:0042787; GO:0004842,"T cell differentiation; cytoplasm; lung development; negative regulation of transcription, DNA-dependent; nucleus; plasma membrane; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity",PF00168;PF00632;PF00397;,1.00E-11,CHOYP_SMUF2.1.1,,,,,,,WWP1_MOUSE,Mus musculus (Mouse),"lung development [GO:0030324]; negative regulation of transcription, DNA-templated [GO:0045892]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; T cell differentiation [GO:0030217]" comp136548_c1_seq5,500,41.2,0.61536527,18,0,,5.00E-19,Q9Y0H4,E3 ubiquitin-protein ligase Su(dx) (EC 6.3.2.-) (Protein suppressor of deltex),E3 ubiquitin-protein ligase Su(dx) (EC 6.3.2.-) (Protein suppressor of deltex),GO:0007219; GO:0005737; GO:0016348; GO:0008587; GO:0008586; GO:0019915; GO:0045746; GO:0005634; GO:0042787; GO:0035209; GO:0031623; GO:0032880; GO:0004842; GO:0048190,Notch signaling pathway; cytoplasm; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; lipid storage; negative regulation of Notch signaling pathway; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; pupal development; receptor internalization; regulation of protein localization; ubiquitin-protein ligase activity; wing disc dorsal/ventral pattern formation,PF00168;PF00632;PF00397;,,,,,,,,,SUDX_DROME,Drosophila melanogaster (Fruit fly),imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; lipid storage [GO:0019915]; negative regulation of Notch signaling pathway [GO:0045746]; Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; pupal development [GO:0035209]; receptor internalization [GO:0031623]; regulation of protein localization [GO:0032880]; wing disc dorsal/ventral pattern formation [GO:0048190] comp136550_c0_seq1,870,43.3333,0.54295663,2,277,female>male,9.00E-06,O07399,3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),GO:0004316; GO:0050661; GO:0030497,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NADP binding; fatty acid elongation,,,,,,,,,,FABG_MYCAV,Mycobacterium avium,fatty acid elongation [GO:0030497] comp136550_c0_seq2,891,44.5567,0.61189101,20,187,,6.00E-26,P21158,C-factor (C signal),C-factor (C signal),GO:0005576; GO:0055114; GO:0016491; GO:0030435,extracellular region; oxidation-reduction process; oxidoreductase activity; sporulation resulting in formation of a cellular spore,PF00106;,,,,,,,,,CSGA_MYXXA,Myxococcus xanthus,sporulation resulting in formation of a cellular spore [GO:0030435] comp136558_c0_seq1,1431,33.0538,0.30838822,512,1102,,,,,,,,,2.00E-15,CHOYP_contig_032397,,,,,,,,, comp136558_c0_seq3,1278,35.8372,0.47022088,346,1197,,3.00E-51,Q5D018,RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A),RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0051028; GO:0016607; GO:0000184; GO:0000166; GO:0000381; GO:0006417,"RNA binding; RNA splicing; cytoplasm; mRNA processing; mRNA transport; nuclear speck; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleotide binding; regulation of alternative mRNA splicing, via spliceosome; regulation of translation",PF00076;,3.00E-87,CHOYP_LOC100180193.1.2,9.00E-105,ruditapes2_c1237,,,,,RBM8A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]" comp136559_c0_seq2,649,38.3667,0.37918161,120,744,,,,,,,,,,,2.00E-15,ruditapes_c2387,,,,,,, comp136561_c0_seq1,2963,40.3982,0.57198959,1526,154,,5.00E-15,Q6NXP0,EF-hand calcium-binding domain-containing protein 12,EF-hand calcium-binding domain-containing protein 12,GO:0005509,calcium ion binding,,2.00E-31,CHOYP_LOC763537.1.1,,,,,,,EFC12_HUMAN,Homo sapiens (Human), comp136562_c1_seq3,709,45.6982,0.59520752,0,0,,7.00E-12,Q95V25,Calcium-activated potassium channel slo-1 (BK channel) (Maxi K channel) (MaxiK) (Slo homolog) (Slowpoke protein 1),Calcium-activated potassium channel slo-1 (BK channel) (Maxi K channel) (MaxiK) (Slo homolog) (Slowpoke protein 1),GO:0031430; GO:0048149; GO:0060072; GO:0040011; GO:0043050; GO:0046928; GO:0042493; GO:0045214; GO:0055120; GO:0045202; GO:0005249; GO:0008076,M band; behavioral response to ethanol; large conductance calcium-activated potassium channel activity; locomotion; pharyngeal pumping; regulation of neurotransmitter secretion; response to drug; sarcomere organization; striated muscle dense body; synapse; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF00520;,1.00E-51,CHOYP_PHUM_PHUM562900.1.1,,,,,,,SLO1_CAEEL,Caenorhabditis elegans,behavioral response to ethanol [GO:0048149]; locomotion [GO:0040011]; modulation of synaptic transmission [GO:0050804]; pharyngeal pumping [GO:0043050]; potassium ion transport [GO:0006813]; regulation of neurotransmitter secretion [GO:0046928]; response to drug [GO:0042493]; sarcomere organization [GO:0045214] comp136562_c1_seq4,1421,46.7277,0.62087628,0,0,,,,,,,,,6.00E-53,CHOYP_KCNT2.1.1,,,,,,,,, comp136562_c2_seq2,1248,43.5096,0.59393805,11,6,,3.00E-87,Q5JUK3,Potassium channel subfamily T member 1 (KCa4.1),Potassium channel subfamily T member 1 (KCa4.1),GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,,,,,,,,,KCNT1_HUMAN,Homo sapiens (Human), comp136564_c1_seq4,2941,40.2924,0.42129205,49,187,,2.00E-14,Q90X44,Nuclear respiratory factor 1 (Nrf-1) (Not really finished protein),Nuclear respiratory factor 1 (Nrf-1) (Not really finished protein),GO:0003677; GO:0070417; GO:0005634; GO:0006355; GO:0014823; GO:0060041; GO:0006351,"DNA binding; cellular response to cold; nucleus; regulation of transcription, DNA-dependent; response to activity; retina development in camera-type eye; transcription, DNA-dependent",PF10492;PF10491;,,,,,,,,,NRF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cellular response to cold [GO:0070417]; multicellular organism development [GO:0007275]; neural retina development [GO:0003407]; photoreceptor cell maintenance [GO:0045494]; regulation of transcription, DNA-templated [GO:0006355]; response to activity [GO:0014823]; retina development in camera-type eye [GO:0060041]; retina homeostasis [GO:0001895]; transcription, DNA-templated [GO:0006351]" comp136568_c0_seq2,1100,42,0.55746882,3,34,,4.00E-06,Q8C729,Protein FAM126B,Protein FAM126B,GO:0005622,intracellular,PF09790;,,,,,,,,,F126B_MOUSE,Mus musculus (Mouse), comp136571_c2_seq4,730,39.1781,0.40462009,69,706,,1.00E-52,Q3T168,Calcyclin-binding protein (CacyBP),Calcyclin-binding protein (CacyBP),GO:0030877; GO:0005641,beta-catenin destruction complex; nuclear envelope lumen,PF04969;PF05002;PF09032;,5.00E-18,CHOYP_SIP.1.1,,,,,,,CYBP_BOVIN,Bos taurus (Bovine), comp136575_c1_seq1,2445,42.454,0.51328603,212,211,,7.00E-166,P58295,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015187; GO:0016021; GO:0005328,glycine transmembrane transporter activity; integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,0,CHOYP_DGRI_GH22876.2.3,,,,,,,SC6A5_RAT,Rattus norvegicus (Rat),"glycine import [GO:0036233]; glycine transport [GO:0015816]; synaptic transmission, glycinergic [GO:0060012]" comp136580_c1_seq1,2230,44.0807,0.86816543,57,3,,1.00E-06,H2A0N4,Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)],Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)],GO:0008061; GO:0006030; GO:0005576,chitin binding; chitin metabolic process; extracellular region,PF01607;PF00092;,,,,,,,,,PIF_PINMG,Pinctada margaritifera (Black-lipped pearl oyster),chitin metabolic process [GO:0006030] comp136580_c3_seq5,2248,37.0552,0.26526549,12,12,,9.00E-19,Q498E6,N-lysine methyltransferase SETD8-B (EC 2.1.1.-) (Histone-lysine N-methyltransferase SETD8-B) (EC 2.1.1.43) (Mitotic phosphoprotein 36) (SET domain-containing protein 8-B),N-lysine methyltransferase KMT5A-B (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-B) (EC 2.1.1.43) (Lysine-specific methylase 5A-B) (Mitotic phosphoprotein 36) (SET domain-containing protein 8-B),GO:0051301; GO:0005694; GO:0018024; GO:0007067; GO:0005634; GO:0006355; GO:0006351,"cell division; chromosome; histone-lysine N-methyltransferase activity; mitosis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET8B_XENLA,Xenopus laevis (African clawed frog),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136583_c0_seq6,2105,34.5843,0.64752695,2545,12819,,2.00E-142,Q16956,78 kDa glucose-regulated protein (GRP-78) (BiP) (Protein 1603),78 kDa glucose-regulated protein (GRP-78) (BiP) (Protein 1603),GO:0005524; GO:0005788,ATP binding; endoplasmic reticulum lumen,PF00012;,0,CHOYP_GRP78.2.5,2.00E-20,ruditapes2_c147,,,,,GRP78_APLCA,Aplysia californica (California sea hare), comp136585_c1_seq4,2591,34.0023,0.45420255,15,288,,2.00E-95,Q6B4U9,Peroxiredoxin-1 (EC 1.11.1.15),Peroxiredoxin-1 (EC 1.11.1.15),GO:0042744; GO:0042470; GO:0005739; GO:0005634; GO:0008379,hydrogen peroxide catabolic process; melanosome; mitochondrion; nucleus; thioredoxin peroxidase activity,PF10417;PF00578;,,,,,,,,,PRDX1_MYOLU,Myotis lucifugus (Little brown bat),cell proliferation [GO:0008283]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NF-kappaB import into nucleus [GO:0042345]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; retina homeostasis [GO:0001895] comp136585_c1_seq9,2559,33.9977,0.46000345,4,59,,2.00E-95,Q6B4U9,Peroxiredoxin-1 (EC 1.11.1.15),Peroxiredoxin-1 (EC 1.11.1.15),GO:0042744; GO:0042470; GO:0005739; GO:0005634; GO:0008379,hydrogen peroxide catabolic process; melanosome; mitochondrion; nucleus; thioredoxin peroxidase activity,PF10417;PF00578;,2.00E-80,CHOYP_ISCW_ISCW010532.4.4,,,,,,,PRDX1_MYOLU,Myotis lucifugus (Little brown bat),cell proliferation [GO:0008283]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NF-kappaB import into nucleus [GO:0042345]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; retina homeostasis [GO:0001895] comp136587_c0_seq1,6396,34.7874,0.69574582,74334,2436801,,3.00E-123,Q9MGM4,Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),GO:0009055; GO:0016021; GO:0046872; GO:0005743; GO:0016491; GO:0070469; GO:0022904,electron carrier activity; integral to membrane; metal ion binding; mitochondrial inner membrane; oxidoreductase activity; respiratory chain; respiratory electron transport chain,PF00032;PF00033;,3.00E-45,CHOYP_LOC100499503.1.1,1.00E-73,ruditapes_c16723,,,,,CYB_DROMA,Drosophila mauritiana (Fruit fly),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp136587_c1_seq1,1660,38.6145,0.63017475,19546,1144908,,0,P67793,Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I),Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I),GO:0009060; GO:0004129; GO:0009055; GO:0020037; GO:0016021; GO:0005506; GO:0005743; GO:0006119; GO:0070469,aerobic respiration; cytochrome-c oxidase activity; electron carrier activity; heme binding; integral to membrane; iron ion binding; mitochondrial inner membrane; oxidative phosphorylation; respiratory chain,PF00115;,7.00E-78,CHOYP_COX1.10.15,1.00E-103,ruditapes_c60,,,,,COX1_CHOOC,Choristoneura occidentalis (Western spruce budworm),aerobic respiration [GO:0009060]; oxidative phosphorylation [GO:0006119] comp136589_c0_seq1,1202,40.3494,0.67542921,8,28521,female>male,1.00E-10,Q3ZCB2,Placenta-specific gene 8 protein,Placenta-specific gene 8 protein,GO:0050873; GO:0003682; GO:0042742; GO:0043066; GO:0040015; GO:0008284; GO:0045944; GO:0009409,brown fat cell differentiation; chromatin binding; defense response to bacterium; negative regulation of apoptotic process; negative regulation of multicellular organism growth; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to cold,PF04749;,,,,,,,,,PLAC8_BOVIN,Bos taurus (Bovine),brown fat cell differentiation [GO:0050873]; defense response to bacterium [GO:0042742]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cold [GO:0009409] comp136590_c0_seq1,1869,44.7298,0.70851652,31,19,,6.00E-83,B4F7A7,Centrosomal protein of 57 kDa (Cep57) (Translokin),Centrosomal protein of 57 kDa (Cep57) (Translokin),GO:0005794; GO:0008543; GO:0005874; GO:0034453; GO:0005815; GO:0005634; GO:0051260; GO:0000060; GO:0007286,"Golgi apparatus; fibroblast growth factor receptor signaling pathway; microtubule; microtubule anchoring; microtubule organizing center; nucleus; protein homooligomerization; protein import into nucleus, translocation; spermatid development",PF14073;PF06657;,,,,,,,,,CEP57_RAT,Rattus norvegicus (Rat),"fibroblast growth factor receptor signaling pathway [GO:0008543]; microtubule anchoring [GO:0034453]; mitotic sister chromatid segregation [GO:0000070]; protein homooligomerization [GO:0051260]; protein import into nucleus, translocation [GO:0000060]; spermatid development [GO:0007286]" comp136590_c0_seq2,1832,44.9236,0.69451569,9,18,,7.00E-43,Q5FWP9,Centrosomal protein cep57l1 (Centrosomal protein 57kDa-like protein 1) (Centrosomal protein of 57 kDa) (Cep57) (XCep57) (Cep57-related protein) (Cep57R),Centrosomal protein cep57l1 (Centrosomal protein 57kDa-like protein 1) (Centrosomal protein of 57 kDa) (Cep57) (XCep57) (Cep57-related protein) (Cep57R),GO:0008608; GO:0005813; GO:0000777; GO:0005737; GO:0043015; GO:0000776; GO:0005876,attachment of spindle microtubules to kinetochore; centrosome; condensed chromosome kinetochore; cytoplasm; gamma-tubulin binding; kinetochore; spindle microtubule,PF14073;PF06657;,6.00E-41,CHOYP_LOC100373990.1.1,,,,,,,CE57L_XENLA,Xenopus laevis (African clawed frog),attachment of spindle microtubules to kinetochore [GO:0008608]; microtubule anchoring [GO:0034453] comp136592_c0_seq1,1411,40.3969,0.98104268,167,2203,,3.00E-46,Q6PBD4,Transcription factor HES-4 (Hairy and enhancer of split 4) (Protein hairy-2),Transcription factor HES-4 (Hairy and enhancer of split 4) (Protein hairy-2),GO:0007219; GO:0008283; GO:0033504; GO:0002088; GO:0007517; GO:0043066; GO:0048642; GO:0000122; GO:0014029; GO:0005634; GO:0021501; GO:0046982; GO:0043565; GO:0006351,"Notch signaling pathway; cell proliferation; floor plate development; lens development in camera-type eye; muscle organ development; negative regulation of apoptotic process; negative regulation of skeletal muscle tissue development; negative regulation of transcription from RNA polymerase II promoter; neural crest formation; nucleus; prechordal plate formation; protein heterodimerization activity; sequence-specific DNA binding; transcription, DNA-dependent",PF07527;PF00010;,6.00E-21,CHOYP_HES1.2.3,2.00E-75,ruditapes_c9435,,,,,HES4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell proliferation [GO:0008283]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest formation [GO:0014029]; Notch signaling pathway [GO:0007219]; prechordal plate formation [GO:0021501]; transcription, DNA-templated [GO:0006351]" comp136595_c0_seq1,1300,38,0.53565578,85,164,,7.00E-39,Q5IFK1,Microcephalin,Microcephalin,GO:0005737; GO:0005815,cytoplasm; microtubule organizing center,PF16589;PF12258;PF12738;,1.00E-17,CHOYP_BRAFLDRAFT_123580.1.1,,,,,,,MCPH1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cerebral cortex development [GO:0021987] comp136597_c2_seq1,1558,38.7035,0.78324248,238,477,,2.00E-16,Q0X0E2,Protein HEXIM2,Protein HEXIM2,GO:0004861; GO:0005737; GO:0045736; GO:0000122; GO:0005634; GO:0017069; GO:0006351,"cyclin-dependent protein serine/threonine kinase inhibitor activity; cytoplasm; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of transcription from RNA polymerase II promoter; nucleus; snRNA binding; transcription, DNA-dependent",PF15313;,2.00E-20,CHOYP_HEXIM1.1.1,,,,,,,HEXI2_BOVIN,Bos taurus (Bovine),"negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp136600_c0_seq2,1738,41.8297,0.38288855,41,30,,,,,,,,,,,1.00E-22,ruditapes2_c2625,,,,,,, comp136605_c0_seq1,2782,40.151,0.41056155,0,0,,3.00E-91,Q5U508,Tubulin-specific chaperone E (Tubulin-folding cofactor E),Tubulin-specific chaperone E (Tubulin-folding cofactor E),GO:0005737; GO:0005856; GO:0007023,cytoplasm; cytoskeleton; post-chaperonin tubulin folding pathway,PF01302;PF14560;,,,,,,,,,TBCE_XENLA,Xenopus laevis (African clawed frog),post-chaperonin tubulin folding pathway [GO:0007023] comp136605_c0_seq2,3537,40.8538,0.42021904,2,18,,7.00E-95,Q5U508,Tubulin-specific chaperone E (Tubulin-folding cofactor E),Tubulin-specific chaperone E (Tubulin-folding cofactor E),GO:0005737; GO:0005856; GO:0007023,cytoplasm; cytoskeleton; post-chaperonin tubulin folding pathway,PF01302;PF14560;,,,,,,,,,TBCE_XENLA,Xenopus laevis (African clawed frog),post-chaperonin tubulin folding pathway [GO:0007023] comp136607_c0_seq1,494,48.583,0.68034133,3,98,,,,,,,,,,,1.00E-15,ruditapes_c28777,,,,,,, comp136608_c3_seq1,1255,35.2191,0.63214888,135,1080,,3.00E-80,Q96L58,"Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)","Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)",GO:0032580; GO:0005797; GO:0000139; GO:0008499; GO:0035250; GO:0005975; GO:0030206; GO:0030204; GO:0047220; GO:0006024; GO:0015012; GO:0016021; GO:0006486,"Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; UDP-galactosyltransferase activity; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; chondroitin sulfate metabolic process; galactosylxylosylprotein 3-beta-galactosyltransferase activity; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process; integral to membrane; protein glycosylation",PF01762;,1.00E-36,CHOYP_LOC585022.1.1,,,,,,,B3GT6_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486] comp136610_c0_seq1,1225,41.0612,0.75616827,125,681,,1.00E-39,Q6ZMW2,Zinc finger protein 782,Zinc finger protein 782,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN782_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136616_c4_seq1,2809,37.2019,0.54714659,0,0,,5.00E-10,Q9W1A4,Protein tamozhennic,Protein tamozhennic,GO:0005737; GO:0007275; GO:0015031; GO:0008270,cytoplasm; multicellular organismal development; protein transport; zinc ion binding,PF09409;,,,,,,,,,TAMO_DROME,Drosophila melanogaster (Fruit fly),multicellular organism development [GO:0007275]; negative regulation of protein import into nucleus [GO:0042308]; protein transport [GO:0015031] comp136616_c4_seq8,2789,37.7555,0.52549992,0,0,,5.00E-10,Q9W1A4,Protein tamozhennic,Protein tamozhennic,GO:0005737; GO:0007275; GO:0015031; GO:0008270,cytoplasm; multicellular organismal development; protein transport; zinc ion binding,PF09409;,,,,,,,,,TAMO_DROME,Drosophila melanogaster (Fruit fly),multicellular organism development [GO:0007275]; negative regulation of protein import into nucleus [GO:0042308]; protein transport [GO:0015031] comp136618_c1_seq1,3017,43.8184,0.55442659,101,479,,7.00E-37,Q8CGE9,Regulator of G-protein signaling 12 (RGS12),Regulator of G-protein signaling 12 (RGS12),GO:0005096; GO:0005737; GO:0005634; GO:0005886; GO:0005057; GO:0038032,GTPase activator activity; cytoplasm; nucleus; plasma membrane; receptor signaling protein activity; termination of G-protein coupled receptor signaling pathway,PF02188;PF00595;PF02196;PF00615;,1.00E-13,CHOYP_LOC100889318.1.1,2.00E-110,ruditapes_c16371,,,,,RGS12_MOUSE,Mus musculus (Mouse),termination of G-protein coupled receptor signaling pathway [GO:0038032] comp136618_c1_seq2,614,42.3453,0.48035455,0,6,,3.00E-35,O43566,Regulator of G-protein signaling 14 (RGS14),Regulator of G-protein signaling 14 (RGS14),GO:0005092; GO:0005096; GO:0016605; GO:0030054; GO:0005813; GO:0007059; GO:0005737; GO:0043197; GO:0045111; GO:0007616; GO:0060291; GO:0005874; GO:0008017; GO:0007067; GO:0070373; GO:0043407; GO:0031914; GO:0016604; GO:0006913; GO:0005886; GO:0048008; GO:0050769; GO:0014069; GO:0045211; GO:0030159; GO:0005057; GO:0043620; GO:0008277; GO:0006979; GO:0007051; GO:0000922; GO:0038032; GO:0008542; GO:0010070,GDP-dissociation inhibitor activity; GTPase activator activity; PML body; cell junction; centrosome; chromosome segregation; cytoplasm; dendritic spine; intermediate filament cytoskeleton; long-term memory; long-term synaptic potentiation; microtubule; microtubule binding; mitosis; negative regulation of ERK1 and ERK2 cascade; negative regulation of MAP kinase activity; negative regulation of synaptic plasticity; nuclear body; nucleocytoplasmic transport; plasma membrane; platelet-derived growth factor receptor signaling pathway; positive regulation of neurogenesis; postsynaptic density; postsynaptic membrane; receptor signaling complex scaffold activity; receptor signaling protein activity; regulation of DNA-dependent transcription in response to stress; regulation of G-protein coupled receptor protein signaling pathway; response to oxidative stress; spindle organization; spindle pole; termination of G-protein coupled receptor signaling pathway; visual learning; zygote asymmetric cell division,PF02196;PF00615;,3.00E-20,CHOYP_LOC100692579.1.1,,,,,,,RGS14_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome segregation [GO:0007059]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitotic nuclear division [GO:0007067]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of synaptic plasticity [GO:0031914]; nucleocytoplasmic transport [GO:0006913]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of neurogenesis [GO:0050769]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; response to oxidative stress [GO:0006979]; spindle organization [GO:0007051]; visual learning [GO:0008542]; zygote asymmetric cell division [GO:0010070] comp136619_c0_seq1,1309,36.7456,1.02240859,18,547,,,,,,,,,2.00E-21,CHOYP_MGC81574.1.1,,,,,,,,, comp136621_c0_seq1,1322,37.3676,0.36952293,159,558,,3.00E-83,P24329,Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),GO:0008097; GO:0016226; GO:0005743; GO:0005759; GO:0005886; GO:0035928; GO:0004792,5S rRNA binding; iron-sulfur cluster assembly; mitochondrial inner membrane; mitochondrial matrix; plasma membrane; rRNA import into mitochondrion; thiosulfate sulfurtransferase activity,PF00581;,,,,,,,,,THTR_RAT,Rattus norvegicus (Rat),"epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" comp136621_c0_seq2,1334,36.8066,0.3775329,167,1022,,1.00E-93,P97532,3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2),3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2),GO:0016784; GO:0030054; GO:0070814; GO:0005739; GO:0043005; GO:0045202; GO:0004792,3-mercaptopyruvate sulfurtransferase activity; cell junction; hydrogen sulfide biosynthetic process; mitochondrion; neuron projection; synapse; thiosulfate sulfurtransferase activity,PF00581;,,,,,,,,,THTM_RAT,Rattus norvegicus (Rat),hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346] comp136623_c0_seq1,232,47.8448,0.52955529,6,23,,3.00E-06,Q62203,Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62),Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62),GO:0008380; GO:0006397; GO:0003676; GO:0005634; GO:0005681; GO:0008270,RNA splicing; mRNA processing; nucleic acid binding; nucleus; spliceosomal complex; zinc ion binding,PF16835;,,,,,,,,,SF3A2_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]" comp136623_c1_seq1,1207,50.6214,0.68608461,3,27,,,,,,,,,4.00E-35,CHOYP_CARNS1.5.6,,,,,,,,, comp136623_c1_seq3,2114,49.9054,0.62331991,35,93,,,,,,,,,3.00E-14,CHOYP_RERE.1.1,,,,,,,,, comp136624_c0_seq1,2156,38.0334,0.67815439,3603,14869,,0,P54814,26S protease regulatory subunit 8 (Protein 18-56),26S protease regulatory subunit 8 (Protein 18-56),GO:0005524; GO:0005737; GO:0017111; GO:0005634; GO:0000502; GO:0030163,ATP binding; cytoplasm; nucleoside-triphosphatase activity; nucleus; proteasome complex; protein catabolic process,PF00004;,0,CHOYP_PRS8.1.1,4.00E-29,ruditapes2_c3331,0,AM859534.p.cg.6,8,,PRS8_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),protein catabolic process [GO:0030163] comp136627_c1_seq1,3242,44.1086,0.52747595,161,1058,,3.00E-75,Q5G266,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,1.00E-51,ruditapes_c15522,,,,,NETR_TRAPH,Trachypithecus phayrei (Phayre's leaf monkey),exocytosis [GO:0006887] comp136628_c0_seq1,855,45.848,0.53590787,0,4,,3.00E-12,Q8XVS8,D-galactonate dehydratase (GalD) (EC 4.2.1.6),D-galactonate dehydratase (GalD) (EC 4.2.1.6),GO:0034194; GO:0009063; GO:0008869; GO:0000287,D-galactonate catabolic process; cellular amino acid catabolic process; galactonate dehydratase activity; magnesium ion binding,PF13378;PF02746;,,,,,,,,,DGOD_RALSO,Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum),cellular amino acid catabolic process [GO:0009063]; D-galactonate catabolic process [GO:0034194] comp136628_c0_seq2,1239,43.8257,0.42666841,2,39,,,,,,,,,5.00E-66,CHOYP_LOC754396.1.1,,,,,,,,, comp136628_c0_seq3,1327,43.8583,0.49551671,2,8,,2.00E-173,Q6INX4,Mitochondrial enolase superfamily member 1 (EC 5.-.-.-),Mitochondrial enolase superfamily member 1 (L-fuconate dehydratase) (EC 4.2.1.68),GO:0016853; GO:0046872; GO:0005739,isomerase activity; metal ion binding; mitochondrion,PF13378;PF02746;,2.00E-115,CHOYP_LOC754396.1.1,,,,,,,ENOF1_XENLA,Xenopus laevis (African clawed frog),cellular carbohydrate catabolic process [GO:0044275] comp136628_c0_seq6,943,45.5992,0.59553244,0,0,,2.00E-112,Q6INX4,Mitochondrial enolase superfamily member 1 (EC 5.-.-.-),Mitochondrial enolase superfamily member 1 (L-fuconate dehydratase) (EC 4.2.1.68),GO:0016853; GO:0046872; GO:0005739,isomerase activity; metal ion binding; mitochondrion,PF13378;PF02746;,,,,,,,,,ENOF1_XENLA,Xenopus laevis (African clawed frog),cellular carbohydrate catabolic process [GO:0044275] comp136637_c0_seq1,1694,35.8914,0.90223268,23,13912,female>male,4.00E-25,Q16WU7,WSCD family member AAEL009094,WSCD family member AAEL009094,GO:0016021; GO:0008146,integral to membrane; sulfotransferase activity,,,,,,,,,,WSCD_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp136638_c0_seq1,1457,42.3473,0.65838113,36,237,,2.00E-34,Q32Q92,Acyl-coenzyme A thioesterase 6 (Acyl-CoA thioesterase 6) (EC 3.1.2.-),Acyl-coenzyme A thioesterase 6 (Acyl-CoA thioesterase 6) (EC 3.1.2.-),GO:0006637; GO:0004091; GO:0005829; GO:0005777; GO:0016790,acyl-CoA metabolic process; carboxylesterase activity; cytosol; peroxisome; thiolester hydrolase activity,PF08840;PF04775;,,,,,,,,,ACOT6_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637] comp136638_c0_seq2,1489,42.1088,0.70921577,68,223,,1.00E-35,Q86TX2,Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.2) (CTE-I) (CTE-Ib) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase),Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.2) (CTE-I) (CTE-Ib) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase),GO:0047617; GO:0006637; GO:0004091; GO:0005829; GO:0001676; GO:0005739; GO:0016290; GO:0000038,acyl-CoA hydrolase activity; acyl-CoA metabolic process; carboxylesterase activity; cytosol; long-chain fatty acid metabolic process; mitochondrion; palmitoyl-CoA hydrolase activity; very long-chain fatty acid metabolic process,PF08840;PF04775;,,,,,,,,,ACOT1_HUMAN,Homo sapiens (Human),acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; very long-chain fatty acid metabolic process [GO:0000038] comp136641_c7_seq1,1050,37.1429,0.17103815,236,497,,2.00E-56,Q5EA33,Ankyrin repeat domain-containing protein 49,Ankyrin repeat domain-containing protein 49,GO:0045893,"positive regulation of transcription, DNA-dependent",,3.00E-35,CHOYP_LOC578101.1.1,,,,,,,ANR49_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]" comp136645_c0_seq1,1639,31.7877,0.63350591,33,32,,,,,,,,,,,6.00E-26,ruditapes2_c1853,,,,,,, comp136646_c0_seq4,1347,36.8968,0.53748036,74,520,,5.00E-42,Q5TYV0,ER membrane protein complex subunit 7,ER membrane protein complex subunit 7,GO:0072546; GO:0030246,ER membrane protein complex; carbohydrate binding,PF09430;,6.00E-46,CHOYP_RL23A.6.6,,,,,,,EMC7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136647_c1_seq1,2169,35.4541,0.55892213,184,462,,4.00E-58,Q8VCE6,"5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)","5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)",GO:0008253; GO:0046079; GO:0046872; GO:0005739; GO:0000166,5'-nucleotidase activity; dUMP catabolic process; metal ion binding; mitochondrion; nucleotide binding,PF06941;,4.00E-13,CHOYP_NT5M.1.1,,,,,,,NT5M_MOUSE,Mus musculus (Mouse),dUMP catabolic process [GO:0046079] comp136648_c0_seq1,3733,30.8331,0.28332698,192,865,,1.00E-84,C3Z724,Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin carrier protein S) (Ubiquitin-protein ligase S),Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (Ubiquitin carrier protein S) (Ubiquitin-protein ligase S),GO:0005524; GO:0051488; GO:0005680; GO:0031145; GO:0051301; GO:0010458; GO:0010994; GO:0070979; GO:0004842,ATP binding; activation of anaphase-promoting complex activity; anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; exit from mitosis; free ubiquitin chain polymerization; protein K11-linked ubiquitination; ubiquitin-protein ligase activity,PF00179;,3.00E-119,CHOYP_LOC100373734.1.1,5.00E-12,ruditapes_c23537,,,,,UBE2S_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] comp136649_c0_seq1,3285,40.2435,0.42199821,295,363,,4.00E-32,E1BD59,E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (Tripartite motif-containing protein 56),E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (Tripartite motif-containing protein 56),GO:0005737; GO:0051607; GO:0032608; GO:0070534; GO:0034340; GO:0004842; GO:0008270,cytoplasm; defense response to virus; interferon-beta production; protein K63-linked ubiquitination; response to type I interferon; ubiquitin-protein ligase activity; zinc ion binding,PF00643;PF13445;,,,,,,,,,TRI56_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; interferon-beta production [GO:0032608]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340] comp136655_c0_seq3,2586,48.7239,0.71674993,11,6,,6.00E-09,Q5VT06,Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),GO:0005813; GO:0005737; GO:0005634; GO:0005819,centrosome; cytoplasm; nucleus; spindle,PF01302;,,,,,,,,,CE350_HUMAN,Homo sapiens (Human),microtubule anchoring [GO:0034453] comp136655_c0_seq4,2559,48.6518,0.7262885,8,3,,6.00E-09,Q5VT06,Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa),GO:0005813; GO:0005737; GO:0005634; GO:0005819,centrosome; cytoplasm; nucleus; spindle,PF01302;,,,,,,,,,CE350_HUMAN,Homo sapiens (Human),microtubule anchoring [GO:0034453] comp136658_c0_seq1,1032,37.5969,0.61863081,500,3526,,8.00E-07,Q0IHH1,N-alpha-acetyltransferase 30 (EC 2.3.1.-) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit),N-alpha-acetyltransferase 30 (EC 2.3.1.88) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit),GO:0008080,N-acetyltransferase activity,PF00583;,,,,,,,,,NAA30_XENLA,Xenopus laevis (African clawed frog), comp136658_c0_seq2,995,37.8894,0.63009035,367,1570,,1.00E-87,Q6DBY2,N-alpha-acetyltransferase 50 (EC 2.3.1.-) (N-acetyltransferase NAT13) (NatE catalytic subunit),N-alpha-acetyltransferase 50 (EC 2.3.1.-) (N-acetyltransferase NAT13) (NatE catalytic subunit),GO:0008080; GO:0005737; GO:0007275,N-acetyltransferase activity; cytoplasm; multicellular organismal development,PF00583;,6.00E-89,CHOYP_BRAFLDRAFT_117937.1.1,,,,,,,NAA50_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mitotic sister chromatid cohesion, centromeric [GO:0071962]; N-terminal protein amino acid acetylation [GO:0006474]; somitogenesis [GO:0001756]" comp136661_c0_seq1,1298,37.5193,0.78897334,88,815,,4.00E-27,Q9CQE1,Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A),Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A),GO:0005829; GO:0005739,cytosol; mitochondrion,PF07978;,1.00E-23,CHOYP_NIPSNAP3A-B.1.1,2.00E-24,ruditapes_c11183,,,,,NPS3B_MOUSE,Mus musculus (Mouse), comp136665_c0_seq4,1220,38.1148,0.39164177,83,660,,6.00E-32,P24528,Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase),Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase),GO:0003677; GO:0006307; GO:0005509; GO:0071479; GO:0071407; GO:0034599; GO:0060644; GO:0003908; GO:0060548; GO:0005634; GO:0045739; GO:0043281; GO:0042493; GO:0045471; GO:0051593; GO:0009636,DNA binding; DNA dealkylation involved in DNA repair; calcium ion binding; cellular response to ionizing radiation; cellular response to organic cyclic compound; cellular response to oxidative stress; mammary gland epithelial cell differentiation; methylated-DNA-[protein]-cysteine S-methyltransferase activity; negative regulation of cell death; nucleus; positive regulation of DNA repair; regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to drug; response to ethanol; response to folic acid; response to toxic substance,PF01035;PF02870;,1.00E-15,CHOYP_LOC100905520.1.1,,,,,,,MGMT_RAT,Rattus norvegicus (Rat),cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; DNA dealkylation involved in DNA repair [GO:0006307]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell death [GO:0060548]; positive regulation of DNA repair [GO:0045739]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636] comp136672_c0_seq2,2328,30.7131,0.71492339,2,18,,,,,,,,,,,3.00E-12,ruditapes_c11664,,,,,,, comp136675_c1_seq2,3025,44.2645,0.34341567,122,188,,0,A0JMY5,NF-X1-type zinc finger protein NFXL1,NF-X1-type zinc finger protein NFXL1,GO:0016021; GO:0005634; GO:0003700; GO:0008270,integral to membrane; nucleus; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF01422;,2.00E-137,CHOYP_NFXL1.1.1,,,,,,,NFXL1_XENLA,Xenopus laevis (African clawed frog), comp136678_c0_seq1,1392,44.181,0.79684363,15,0,,7.00E-51,Q6GNV7,Disrupted in renal carcinoma protein 2 homolog,Disrupted in renal carcinoma protein 2 homolog,GO:0016021; GO:0005765; GO:0055085,integral to membrane; lysosomal membrane; transmembrane transport,PF07690;,,,,,,,,,DIRC2_XENLA,Xenopus laevis (African clawed frog),transmembrane transport [GO:0055085] comp136681_c0_seq1,1687,40.1897,0.81558817,98,94,,6.00E-75,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,2.00E-28,CHOYP_SACS.3.17,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp136684_c0_seq1,896,41.0714,0.54528943,0,11,,,,,,,,,1.00E-109,CHOYP_LOC100371628.1.1,,,,,,,,, comp136684_c0_seq3,1264,38.212,0.51894229,44,141,,8.00E-56,Q9CPW7,Zinc finger matrin-type protein 2,Zinc finger matrin-type protein 2,GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,PF12171;,2.00E-109,CHOYP_LOC100371628.1.1,,,,,,,ZMAT2_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp136686_c0_seq2,514,44.7471,0.47773836,48,261,,8.00E-50,Q5ZJQ3,Protein lin-52 homolog,Protein lin-52 homolog,GO:0070176; GO:0007049; GO:0006351,"DRM complex; cell cycle; transcription, DNA-dependent",PF10044;,7.00E-34,CHOYP_LIN52.2.2,1.00E-66,ruditapes_c18854,,,,,LIN52_CHICK,Gallus gallus (Chicken),"cell cycle [GO:0007049]; transcription, DNA-templated [GO:0006351]" comp136693_c0_seq2,1826,38.8828,0.39405207,69,175,,1.00E-32,Q9UKX7,Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50),Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50),GO:0005975; GO:0019221; GO:0015758; GO:0046907; GO:0051028; GO:0007077; GO:0031965; GO:0005643; GO:0005654; GO:0015031; GO:0010827; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; intracellular transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear membrane; nuclear pore; nucleoplasm; protein transport; regulation of glucose transport; small molecule metabolic process; transmembrane transport; viral process,PF08911;PF00638;,4.00E-12,CHOYP_LOC100748625.1.1,,,,,,,NUP50_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp136694_c1_seq1,2294,42.7637,0.3637115,0,0,,3.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq13,4073,41.2718,0.37094326,0,0,,9.00E-09,Q8IWY4,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0007512; GO:0007596; GO:0005509; GO:0045446; GO:0009897; GO:0005615; GO:0019897; GO:0042802; GO:0006954; GO:0009791; GO:0046982; GO:0051260,adult heart development; blood coagulation; calcium ion binding; endothelial cell differentiation; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; identical protein binding; inflammatory response; post-embryonic development; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_HUMAN,Homo sapiens (Human),adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260] comp136694_c1_seq16,4280,41.4486,0.36629557,0,0,,9.00E-12,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp136694_c1_seq17,2667,41.8823,0.34633613,0,0,,4.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq18,2102,41.96,0.37978905,0,0,,4.00E-09,Q8IWY4,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0007512; GO:0007596; GO:0005509; GO:0045446; GO:0009897; GO:0005615; GO:0019897; GO:0042802; GO:0006954; GO:0009791; GO:0046982; GO:0051260,adult heart development; blood coagulation; calcium ion binding; endothelial cell differentiation; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; identical protein binding; inflammatory response; post-embryonic development; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_HUMAN,Homo sapiens (Human),adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260] comp136694_c1_seq20,2166,41.9668,0.38957028,0,0,,3.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq22,3243,42.4298,0.34625273,0,0,,4.00E-08,Q6NZL8,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0005509; GO:0009897; GO:0005615; GO:0019897; GO:0046982; GO:0051260,calcium ion binding; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp136694_c1_seq23,4265,41.7351,0.36260049,0,0,,9.00E-12,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp136694_c1_seq24,2460,41.626,0.35219156,0,0,,2.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq25,1554,42.6641,0.3419588,0,0,,5.00E-06,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp136694_c1_seq27,3896,41.4271,0.36070867,0,0,,8.00E-12,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp136694_c1_seq31,4137,41.286,0.37639181,0,0,,7.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq33,4344,41.4595,0.37150836,0,0,,5.00E-08,Q6NZL8,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0005509; GO:0009897; GO:0005615; GO:0019897; GO:0046982; GO:0051260,calcium ion binding; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp136694_c1_seq36,3036,42.2596,0.35085666,0,0,,5.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq38,2309,42.2261,0.37053616,0,0,,2.00E-08,Q6NZL8,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0005509; GO:0009897; GO:0005615; GO:0019897; GO:0046982; GO:0051260,calcium ion binding; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp136694_c1_seq39,2874,40.7794,0.39474804,0,0,,1.00E-11,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp136694_c1_seq40,3051,41.8551,0.35582923,0,0,,4.00E-08,Q6NZL8,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0005509; GO:0009897; GO:0005615; GO:0019897; GO:0046982; GO:0051260,calcium ion binding; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp136694_c1_seq41,2844,41.6315,0.36167906,0,0,,4.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq6,1718,42.0256,0.37047141,0,0,,1.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136694_c1_seq8,1925,42.3377,0.36055664,0,0,,3.00E-09,Q8IWY4,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0007512; GO:0007596; GO:0005509; GO:0045446; GO:0009897; GO:0005615; GO:0019897; GO:0042802; GO:0006954; GO:0009791; GO:0046982; GO:0051260,adult heart development; blood coagulation; calcium ion binding; endothelial cell differentiation; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; identical protein binding; inflammatory response; post-embryonic development; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_HUMAN,Homo sapiens (Human),adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260] comp136694_c1_seq9,3689,41.2307,0.3654748,0,0,,4.00E-12,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp136696_c0_seq1,1437,40.2923,0.59035504,49,332,,5.00E-45,Q9BUJ0,Alpha/beta hydrolase domain-containing protein 14A (Abhydrolase domain-containing protein 14A) (EC 3.-.-.-),Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A),GO:0005737; GO:0016787; GO:0016021,cytoplasm; hydrolase activity; integral to membrane,PF12697;,,,,,,,,,ABHEA_HUMAN,Homo sapiens (Human), comp136699_c0_seq1,1504,34.8404,0.6899589,7661,66739,,5.00E-15,Q9FVI2,Actin-depolymerizing factor 1 (ADF-1),Actin-depolymerizing factor 1 (ADF-1),GO:0015629; GO:0030042,actin cytoskeleton; actin filament depolymerization,PF00241;,,,,,,,,,ADF1_PETHY,Petunia hybrida (Petunia),actin filament depolymerization [GO:0030042] comp136704_c0_seq1,3158,39.3604,0.41022499,458,2021,,3.00E-143,Q5RDL2,ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24),ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF00271;,4.00E-135,CHOYP_DDX24.1.1,,,,,,,DDX24_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp136710_c0_seq1,2194,37.2835,0.44979518,9,0,,1.00E-57,P62343,Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCDPK1) (PfCPK),Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCDPK1) (PfCPK),GO:0005524; GO:0005509; GO:0016020; GO:0004674,ATP binding; calcium ion binding; membrane; protein serine/threonine kinase activity,PF13499;PF00069;,3.00E-160,CHOYP_LOC100650648.2.2,,,,,,,CDPK1_PLAFK,Plasmodium falciparum (isolate K1 / Thailand), comp136710_c0_seq3,2156,37.8479,0.44515122,1,8,,1.00E-155,Q91YS8,Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha),Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha),GO:0005524; GO:0005954; GO:0004683; GO:0007049; GO:0005737; GO:0006913; GO:0005634; GO:0060999; GO:0051149; GO:0010976; GO:0046827; GO:0071902; GO:0051835; GO:0051147; GO:0043393; GO:0007165,ATP binding; calcium- and calmodulin-dependent protein kinase complex; calmodulin-dependent protein kinase activity; cell cycle; cytoplasm; nucleocytoplasmic transport; nucleus; positive regulation of dendritic spine development; positive regulation of muscle cell differentiation; positive regulation of neuron projection development; positive regulation of protein export from nucleus; positive regulation of protein serine/threonine kinase activity; positive regulation of synapse structural plasticity; regulation of muscle cell differentiation; regulation of protein binding; signal transduction,PF00069;,3.00E-160,CHOYP_LOC100650648.2.2,,,,,,,KCC1A_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; negative regulation of protein binding [GO:0032091]; nucleocytoplasmic transport [GO:0006913]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of muscle cell differentiation [GO:0051147]; regulation of protein binding [GO:0043393]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165] comp136710_c0_seq4,881,41.8842,0.4912439,0,6,,4.00E-124,A8X6H4,Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI),Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI),GO:0005524; GO:0004683; GO:0046872; GO:0007275; GO:0005634,ATP binding; calmodulin-dependent protein kinase activity; metal ion binding; multicellular organismal development; nucleus,PF00069;,,,,,,,,,CMK1_CAEBR,Caenorhabditis briggsae,multicellular organism development [GO:0007275] comp136713_c0_seq4,4207,44.9489,0.53374048,56,30,,3.00E-132,E9Q1U1,Coiled-coil domain-containing protein 171,Coiled-coil domain-containing protein 171,,,,9.00E-145,CHOYP_CC171.1.1,,,,,,,CC171_MOUSE,Mus musculus (Mouse), comp136713_c0_seq5,716,43.0168,0.72091944,0,0,,2.00E-09,Q6TFL3,Coiled-coil domain-containing protein 171,Coiled-coil domain-containing protein 171,,,,,,,,,,,,CC171_HUMAN,Homo sapiens (Human), comp136716_c0_seq2,1605,43.2399,0.46696536,20,0,,1.00E-93,Q04073,DNA-binding protein P3A2,DNA-binding protein P3A2,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10492;PF10491;,5.00E-48,CHOYP_P3A2.3.3,,,,,,,P3A2_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136717_c0_seq1,2057,40.5445,1.1716855,143,567,,6.00E-31,P69478,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),GO:0000139; GO:0001537; GO:0050659; GO:0016051; GO:0002063; GO:0047756; GO:0030206; GO:0048589; GO:0042733; GO:0048703; GO:0016021; GO:0043066; GO:0030512; GO:0033037; GO:0036342; GO:0009791; GO:0042127; GO:0007585,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; carbohydrate biosynthetic process; chondrocyte development; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; developmental growth; embryonic digit morphogenesis; embryonic viscerocranium morphogenesis; integral to membrane; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; polysaccharide localization; post-anal tail morphogenesis; post-embryonic development; regulation of cell proliferation; respiratory gaseous exchange,PF03567;,,,,,,,,,CHSTB_RAT,Rattus norvegicus (Rat),carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585] comp136718_c0_seq3,277,42.5993,0.24069578,0,1,,1.00E-07,Q96AY4,Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0000922,cell division; cytoplasm; microtubule organizing center; midbody; mitosis; spindle pole,PF12770;PF13176;PF13181;,,,,,,,,,TTC28_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp136719_c0_seq1,1638,44.8107,0.62506753,0,0,,0,Q5E9P9,"Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)","Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)",GO:0006565; GO:0046655; GO:0004372; GO:0006544; GO:0005739; GO:0005634; GO:0051262; GO:0009113; GO:0030170; GO:0035999,L-serine catabolic process; folic acid metabolic process; glycine hydroxymethyltransferase activity; glycine metabolic process; mitochondrion; nucleus; protein tetramerization; purine nucleobase biosynthetic process; pyridoxal phosphate binding; tetrahydrofolate interconversion,PF00464;,,,,,,,,,GLYC_BOVIN,Bos taurus (Bovine),glycine metabolic process [GO:0006544]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] comp136719_c0_seq3,1211,38.2329,0.75862121,10,4,,,,,,,,,,,9.00E-22,ruditapes_c2371,,,,,,, comp136719_c0_seq4,2121,41.3956,0.65534981,4,0,,0,P34897,"Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)","Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)",GO:0008732; GO:0006564; GO:0016597; GO:0003682; GO:0019264; GO:0004372; GO:0015630; GO:0005743; GO:0005758; GO:0042645; GO:0006730; GO:0008284; GO:0051289; GO:0030170; GO:0035999,L-allo-threonine aldolase activity; L-serine biosynthetic process; amino acid binding; chromatin binding; glycine biosynthetic process from serine; glycine hydroxymethyltransferase activity; microtubule cytoskeleton; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial nucleoid; one-carbon metabolic process; positive regulation of cell proliferation; protein homotetramerization; pyridoxal phosphate binding; tetrahydrofolate interconversion,PF00464;,2.00E-167,CHOYP_SHMT2.1.1,,,,,,,GLYM_HUMAN,Homo sapiens (Human),folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] comp136723_c0_seq1,865,41.1561,0.60138969,41,138,,7.00E-35,Q8N8Q1,Cytochrome b561 domain-containing protein 1,Cytochrome b561 domain-containing protein 1,GO:0016021; GO:0046872; GO:0055114,integral to membrane; metal ion binding; oxidation-reduction process,PF03188;,,,,,,,,,C56D1_HUMAN,Homo sapiens (Human),oxidation-reduction process [GO:0055114] comp136726_c0_seq1,1772,41.0835,0.94596067,4,48,,1.00E-28,Q80T74,Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),,,PF07707;PF00651;PF01344;,,,,,,,,,KLH29_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp136726_c0_seq2,1760,41.1364,0.9359881,0,2,,9.00E-29,Q80T74,Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9),,,PF07707;PF00651;PF01344;,,,,,,,,,KLH29_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp136730_c0_seq1,2727,42.2809,0.38830981,142,665,,1.00E-75,Q99728,BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-),BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-),GO:0070531; GO:0031436; GO:0006281; GO:0003723; GO:0007050; GO:0005737; GO:0019900; GO:0043066; GO:0031441; GO:0046826; GO:0043065; GO:0045732; GO:0085020; GO:0042325; GO:0006974; GO:0001894; GO:0004842; GO:0008270,BRCA1-A complex; BRCA1-BARD1 complex; DNA repair; RNA binding; cell cycle arrest; cytoplasm; kinase binding; negative regulation of apoptotic process; negative regulation of mRNA 3'-end processing; negative regulation of protein export from nucleus; positive regulation of apoptotic process; positive regulation of protein catabolic process; protein K6-linked ubiquitination; regulation of phosphorylation; response to DNA damage stimulus; tissue homeostasis; ubiquitin-protein ligase activity; zinc ion binding,PF12796;,,,,,,,,,BARD1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA 3'-end processing [GO:0031441]; negative regulation of protein export from nucleus [GO:0046826]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of phosphorylation [GO:0042325]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; tissue homeostasis [GO:0001894] comp136733_c0_seq1,1177,40.6117,0.5208245,0,5,,2.00E-06,P68352,COP9 signalosome complex subunit 1 (CSN complex subunit 1) (Constitutive photomorphogenesis protein 11) (FUSCA protein 6) (FUSCA6) (Fragment),COP9 signalosome complex subunit 1 (CSN complex subunit 1) (Constitutive photomorphogenesis protein 11) (FUSCA protein 6) (FUSCA6) (Fragment),GO:0008180; GO:0005737; GO:0007275; GO:0009585,"COP9 signalosome; cytoplasm; multicellular organismal development; red, far-red light phototransduction",,,,,,,,,,CSN1_BRAOL,Brassica oleracea (Wild cabbage),"COP9 signalosome assembly [GO:0010387]; cullin deneddylation [GO:0010388]; multicellular organism development [GO:0007275]; red, far-red light phototransduction [GO:0009585]" comp136733_c0_seq2,1897,41.6447,0.46806729,91,144,,0,Q6NRT5,COP9 signalosome complex subunit 1 (Signalosome subunit 1),COP9 signalosome complex subunit 1 (Signalosome subunit 1),GO:0008180; GO:0005737,COP9 signalosome; cytoplasm,PF01399;PF10602;,0,CHOYP_BRAFLDRAFT_116394.1.1,,,,,,,CSN1_XENLA,Xenopus laevis (African clawed frog),COP9 signalosome assembly [GO:0010387]; cullin deneddylation [GO:0010388] comp136738_c2_seq3,1987,39.0035,0.52046789,0,0,,3.00E-83,Q64395,"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (Fragment)","Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (Fragment)",GO:0004114; GO:0004112; GO:0005737; GO:0046872; GO:0007165,"3',5'-cyclic-nucleotide phosphodiesterase activity; cyclic-nucleotide phosphodiesterase activity; cytoplasm; metal ion binding; signal transduction",PF00233;,1.00E-157,CHOYP_LOC100376069.3.5,,,,,,,PDE1B_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),signal transduction [GO:0007165] comp136738_c2_seq4,2023,39.1992,0.49213613,0,0,,1.00E-180,Q14123,"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)","Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)",GO:0007202; GO:0004117; GO:0005829; GO:0007173; GO:0008543; GO:0045087; GO:0046872; GO:0048011,activation of phospholipase C activity; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; metal ion binding; neurotrophin TRK receptor signaling pathway,PF00233;PF08499;,9.00E-179,CHOYP_LOC100376069.3.5,,,6.00E-87,AM868587.p.cg.6,5,male gonad,PDE1C_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp136738_c2_seq5,658,40.7295,0.52674972,0,0,,,,,,,,,1.00E-81,CHOYP_LOC100376069.2.5,,,,,,,,, comp136740_c0_seq1,1244,42.0418,0.35442473,313,1750,,2.00E-101,Q66I84,Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog),Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog),GO:0003677; GO:0006260; GO:0000785; GO:0034088; GO:0005634; GO:0006275,DNA binding; DNA replication; chromatin; maintenance of mitotic sister chromatid cohesion; nucleus; regulation of DNA replication,PF09724;,,,,,,,,,DCC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA replication [GO:0006260]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; regulation of DNA replication [GO:0006275] comp136744_c2_seq1,2631,43.9377,0.45204978,0,5,,0,P55162,Membrane-associated protein Hem (dHem-2),Membrane-associated protein Hem (dHem-2),GO:0031209; GO:0007409; GO:0030031; GO:0007417; GO:0008407; GO:0030866; GO:0016021; GO:0007520; GO:0007528; GO:0001764; GO:0006909; GO:0005886; GO:0008360,SCAR complex; axonogenesis; cell projection assembly; central nervous system development; chaeta morphogenesis; cortical actin cytoskeleton organization; integral to membrane; myoblast fusion; neuromuscular junction development; neuron migration; phagocytosis; plasma membrane; regulation of cell shape,PF09735;,0,CHOYP_NCKP1.1.4,,,,,,,HEM_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; cell adhesion mediated by integrin [GO:0033627]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; neuron migration [GO:0001764]; oocyte growth [GO:0001555]; phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360] comp136744_c2_seq2,1143,44.9694,0.43714878,0,7,,,,,,,,,1.00E-46,CHOYP_NCKP1.4.4,,,,,,,,, comp136744_c2_seq3,2652,44.0422,0.45398602,0,0,,0,P55162,Membrane-associated protein Hem (dHem-2),Membrane-associated protein Hem (dHem-2),GO:0031209; GO:0007409; GO:0030031; GO:0007417; GO:0008407; GO:0030866; GO:0016021; GO:0007520; GO:0007528; GO:0001764; GO:0006909; GO:0005886; GO:0008360,SCAR complex; axonogenesis; cell projection assembly; central nervous system development; chaeta morphogenesis; cortical actin cytoskeleton organization; integral to membrane; myoblast fusion; neuromuscular junction development; neuron migration; phagocytosis; plasma membrane; regulation of cell shape,PF09735;,0,CHOYP_NCKP1.2.4,,,,,,,HEM_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; cell adhesion mediated by integrin [GO:0033627]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; neuron migration [GO:0001764]; oocyte growth [GO:0001555]; phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360] comp136744_c2_seq5,1353,44.7154,0.46474626,7,13,,,,,,,,,2.00E-46,CHOYP_NCKP1.4.4,,,,,,,,, comp136744_c2_seq8,1444,42.7285,0.44207338,0,0,,,,,,,,,0,CHOYP_NCKP1.2.4,,,,,,,,, comp136746_c0_seq1,2060,43.4466,0.54415854,118,308,,0,Q8C3P7,N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) (EC 2.1.1.62) (Methyltransferase-like protein 3),N6-adenosine-methyltransferase subunit METTL3 (EC 2.1.1.62) (Methyltransferase-like protein 3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70),GO:0003723; GO:0016422; GO:0001734; GO:0016607; GO:0005634,RNA binding; mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity; mRNA (N6-adenosine)-methyltransferase activity; nuclear speck; nucleus,PF05063;,2.00E-155,CHOYP_PHUM_PHUM423190.1.1,,,,,,,MTA70_MOUSE,Mus musculus (Mouse),"adenosine to inosine editing [GO:0006382]; circadian rhythm [GO:0007623]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cap-independent translational initiation [GO:1903679]; primary miRNA methylation [GO:1990744]; primary miRNA processing [GO:0031053]; RNA methylation [GO:0001510]; stem cell population maintenance [GO:0019827]" comp136747_c3_seq1,1615,30.8978,0.42252525,5253,3433,,1.00E-53,P60522,Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16),Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16),GO:0005794; GO:0005776; GO:0000421; GO:0006914; GO:0031410; GO:1901799; GO:0015031,Golgi apparatus; autophagic vacuole; autophagic vacuole membrane; autophagy; cytoplasmic vesicle; negative regulation of proteasomal protein catabolic process; protein transport,PF02991;,3.00E-88,CHOYP_BRAFLDRAFT_276662.1.1,2.00E-102,ruditapes_c18039,,,,,GBRL2_RAT,Rattus norvegicus (Rat),autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; mitophagy [GO:0000422]; negative regulation of proteasomal protein catabolic process [GO:1901799]; protein transport [GO:0015031] comp136748_c0_seq1,2350,45.7872,0.41407516,107,207,,,,,,,,,,,5.00E-22,ruditapes_c14699,,,,,,, comp136748_c2_seq1,456,44.9561,0.95807589,10,6,,3.00E-60,B4HF64,Forkhead box protein O,Forkhead box protein O,GO:0007049; GO:0030154; GO:0005737; GO:0042593; GO:0010259; GO:0030308; GO:0008285; GO:0046627; GO:0005634; GO:0019216; GO:0043565; GO:0003700; GO:0006351,"cell cycle; cell differentiation; cytoplasm; glucose homeostasis; multicellular organismal aging; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of insulin receptor signaling pathway; nucleus; regulation of lipid metabolic process; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,3.00E-82,CHOYP_LOC100123890.1.1,,,,,,,FOXO_DROSE,Drosophila sechellia (Fruit fly),"cell cycle [GO:0007049]; cell differentiation [GO:0030154]; glucose homeostasis [GO:0042593]; multicellular organism aging [GO:0010259]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136751_c0_seq1,2129,39.5021,0.53908554,864,3364,,9.00E-170,Q13867,Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40),Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40),GO:0004177; GO:0002474; GO:0004180; GO:0004197; GO:0005829; GO:0005634; GO:0000209; GO:0006508; GO:0042493; GO:0009636,aminopeptidase activity; antigen processing and presentation of peptide antigen via MHC class I; carboxypeptidase activity; cysteine-type endopeptidase activity; cytosol; nucleus; protein polyubiquitination; proteolysis; response to drug; response to toxic substance,PF03051;,2.00E-34,CHOYP_BLMH.1.1,,,,,,,BLMH_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; response to drug [GO:0042493]; response to toxic substance [GO:0009636] comp136754_c0_seq2,1205,41.0788,0.45304314,0,0,,3.00E-41,Q9SU14,Nudix hydrolase 7 (AtNUDT7) (EC 3.6.1.-) (ADP-ribose pyrophosphatase) (EC 3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22) (Protein GROWTH FACTOR GENE 1),Nudix hydrolase 7 (AtNUDT7) (EC 3.6.1.-) (ADP-ribose pyrophosphatase) (EC 3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22) (Protein GROWTH FACTOR GENE 1),GO:0047631; GO:0000210; GO:0005737; GO:0046872; GO:0005634; GO:0005886,ADP-ribose diphosphatase activity; NAD+ diphosphatase activity; cytoplasm; metal ion binding; nucleus; plasma membrane,PF00293;,,,,,,,,,NUDT7_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp136754_c0_seq5,1423,39.6346,0.51952522,0,0,,2.00E-75,P53370,Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG),Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG),GO:0008083; GO:0016787; GO:0005739; GO:0005634,growth factor activity; hydrolase activity; mitochondrion; nucleus,PF00293;,,,,,,,,,NUDT6_HUMAN,Homo sapiens (Human), comp136754_c0_seq7,1054,40.8918,0.54705779,0,0,,5.00E-74,P53370,Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG),Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG),GO:0008083; GO:0016787; GO:0005739; GO:0005634,growth factor activity; hydrolase activity; mitochondrion; nucleus,PF00293;,,,,,,,,,NUDT6_HUMAN,Homo sapiens (Human), comp136755_c0_seq1,1838,33.1338,1.09110065,5,5941,female>male,2.00E-17,P04630,Calmodulin-like protein,Calmodulin-like protein,GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALL_CAEEL,Caenorhabditis elegans, comp136756_c0_seq1,1831,36.9197,0.27423226,46,117,,7.00E-74,Q3U2U7,"Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial)","Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial)",GO:0005507; GO:0008168; GO:0005739; GO:0005840; GO:0006412,copper ion binding; methyltransferase activity; mitochondrion; ribosome; translation,PF09243;,,,,,,,,,MET17_MOUSE,Mus musculus (Mouse),translation [GO:0006412] comp136760_c0_seq2,1412,47.3088,0.2689454,19,103,,2.00E-153,Q6DCD1,FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-),FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-),GO:0005975; GO:0016301; GO:0016773,"carbohydrate metabolic process; kinase activity; phosphotransferase activity, alcohol group as acceptor",PF02782;PF00370;,6.00E-21,CHOYP_FGGY.1.1,,,,,,,FGGY_XENLA,Xenopus laevis (African clawed frog),carbohydrate metabolic process [GO:0005975] comp136765_c1_seq1,1317,39.104,0.91561005,41,285,,9.00E-29,Q86WC6,Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1) (Toonin),Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1) (Toonin),GO:0010923; GO:0019902; GO:0004864,negative regulation of phosphatase activity; phosphatase binding; protein phosphatase inhibitor activity,,2.00E-51,CHOYP_PPR27.1.1,7.00E-62,ruditapes2_c2143,,,,,PPR27_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923] comp136774_c1_seq1,1508,36.6711,0.63939013,648,6272,,6.00E-73,Q7ZUC7,Prostaglandin E synthase 2 (EC 4.1.2.-) (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2),Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2),GO:0045454; GO:0009055; GO:0016021; GO:0001516; GO:0050220; GO:0015035,cell redox homeostasis; electron carrier activity; integral to membrane; prostaglandin biosynthetic process; prostaglandin-E synthase activity; protein disulfide oxidoreductase activity,PF00462;PF00043;,,,,,,,,,PGES2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516] comp136777_c0_seq1,1250,38.96,0.46461641,160,1402,,2.00E-81,O01391,Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Ubiquitin thioesterase),Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Ubiquitin thioesterase),GO:0008234; GO:0005737; GO:0004221; GO:0006511,cysteine-type peptidase activity; cytoplasm; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF01088;,5.00E-28,CHOYP_UCHL.1.1,7.00E-74,ruditapes_c19116,,,,,UCHL_APLCA,Aplysia californica (California sea hare),ubiquitin-dependent protein catabolic process [GO:0006511] comp136778_c0_seq1,1901,39.8211,0.5890536,1160,5554,,1.00E-115,P07858,Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain],Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain],GO:0097067; GO:0030574; GO:0004197; GO:0036021; GO:0022617; GO:0005615; GO:0045087; GO:0042470; GO:0005739; GO:0005730; GO:0048471; GO:0006508; GO:0042981; GO:0050790; GO:0002224,cellular response to thyroid hormone stimulus; collagen catabolic process; cysteine-type endopeptidase activity; endolysosome lumen; extracellular matrix disassembly; extracellular space; innate immune response; melanosome; mitochondrion; nucleolus; perinuclear region of cytoplasm; proteolysis; regulation of apoptotic process; regulation of catalytic activity; toll-like receptor signaling pathway,PF00112;PF08127;,3.00E-102,CHOYP_CATB.2.2,4.00E-117,ruditapes2_c848,,,,,CATB_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718] comp136782_c0_seq1,1245,32.0482,0.79781836,688,3883,,5.00E-59,P31478,V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F),V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F),GO:0015991; GO:0046961; GO:0033180,"ATP hydrolysis coupled proton transport; proton-transporting ATPase activity, rotational mechanism; proton-transporting V-type ATPase, V1 domain",PF01990;,2.00E-46,CHOYP_LOC100113561.1.1,1.00E-95,ruditapes2_c2310,,,,,VATF_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),ATP hydrolysis coupled proton transport [GO:0015991] comp136785_c0_seq1,1800,42.2222,0.42811711,3,6,,2.00E-115,Q8NFH3,Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42),Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42),GO:0005975; GO:0051301; GO:0007059; GO:0000777; GO:0019221; GO:0005829; GO:0015758; GO:0051028; GO:0007067; GO:0007077; GO:0031080; GO:0015031; GO:0010827; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; cell division; chromosome segregation; condensed chromosome kinetochore; cytokine-mediated signaling pathway; cytosol; glucose transport; mRNA transport; mitosis; mitotic nuclear envelope disassembly; nuclear pore outer ring; protein transport; regulation of glucose transport; small molecule metabolic process; transmembrane transport; viral process,PF00400;,,,,,,,,,NUP43_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; sister chromatid cohesion [GO:0007062]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp136785_c0_seq3,1538,43.6931,0.5236993,12,0,,8.00E-18,Q54Z22,Nuclear pore complex protein nup43 (Nucleoporin nup43),Nuclear pore complex protein nup43 (Nucleoporin nup43),GO:0051028; GO:0031965; GO:0005643; GO:0015031,mRNA transport; nuclear membrane; nuclear pore; protein transport,,,,,,,,,,NUP43_DICDI,Dictyostelium discoideum (Slime mold),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp136789_c0_seq1,991,41.0696,0.91490797,65,388,,3.00E-87,Q5M7T9,Threonine synthase-like 2 (TSH2) (EC 4.2.3.-),Threonine synthase-like 2 (TSH2) (EC 4.2.3.-),GO:0046360; GO:0016311; GO:0016829; GO:0030170; GO:0070905; GO:0009071,2-oxobutyrate biosynthetic process; dephosphorylation; lyase activity; pyridoxal phosphate binding; serine binding; serine family amino acid catabolic process,PF00291;PF14821;,,,,,,,,,THNS2_RAT,Rattus norvegicus (Rat),2-oxobutyrate biosynthetic process [GO:0046360]; dephosphorylation [GO:0016311]; serine family amino acid catabolic process [GO:0009071] comp136789_c0_seq3,659,45.3718,0.90123102,36,102,,1.00E-57,Q42598,Threonine synthase (TS) (EC 4.2.3.1),Threonine synthase (TS) (EC 4.2.3.1),GO:0005829; GO:0005634; GO:0030170; GO:0009088; GO:0004795,cytosol; nucleus; pyridoxal phosphate binding; threonine biosynthetic process; threonine synthase activity,PF00291;PF14821;,1.00E-45,CHOYP_THNS2.1.1,,,,,,,THRC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),threonine biosynthetic process [GO:0009088] comp136791_c0_seq2,1887,34.6052,0.54983763,100,200,,1.00E-57,Q9VMW8,Mannose-P-dolichol utilization defect 1 protein homolog,Mannose-P-dolichol utilization defect 1 protein homolog,GO:0016021; GO:0006810,integral to membrane; transport,PF04193;,1.00E-12,CHOYP_DGRI_GH13077.1.1,,,,,,,MPU1_DROME,Drosophila melanogaster (Fruit fly),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486]; transport [GO:0006810] comp136792_c0_seq1,1267,37.0955,0.70183251,269,1972,,2.00E-42,A8Y5U1,UPF0600 protein C5orf51 homolog,UPF0600 protein C5orf51 homolog,,,,,,1.00E-21,ruditapes_c14083,,,,,CE051_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136793_c0_seq1,1518,37.9447,0.69712591,4727,13286,,9.00E-106,Q9DCT2,"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit)","NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit)",GO:0008137; GO:0003954; GO:0005747; GO:0030308; GO:2001243; GO:0072593,NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity; mitochondrial respiratory chain complex I; negative regulation of cell growth; negative regulation of intrinsic apoptotic signaling pathway; reactive oxygen species metabolic process,PF00329;,8.00E-45,CHOYP_DSIM_GD13354.1.1,5.00E-121,ruditapes2_c229,,,,,NDUS3_MOUSE,Mus musculus (Mouse),negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; reactive oxygen species metabolic process [GO:0072593]; substantia nigra development [GO:0021762] comp136797_c0_seq2,1638,33.4554,0.45906707,5,88,,7.00E-14,Q9UTI2,Glutaredoxin-2,Glutaredoxin-2,GO:0045454; GO:0009055; GO:0004602; GO:0004364; GO:0005739; GO:0015035; GO:0019430,cell redox homeostasis; electron carrier activity; glutathione peroxidase activity; glutathione transferase activity; mitochondrion; protein disulfide oxidoreductase activity; removal of superoxide radicals,PF00462;,,,8.00E-18,ruditapes2_c1949,,,,,GLRX2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430] comp136798_c1_seq1,973,42.2405,0.58491534,106,174,,4.00E-35,P54277,PMS1 protein homolog 1 (DNA mismatch repair protein PMS1),PMS1 protein homolog 1 (DNA mismatch repair protein PMS1),GO:0005524; GO:0016887; GO:0032389; GO:0032407; GO:0006298; GO:0030983; GO:0007131; GO:0003697,ATP binding; ATPase activity; MutLalpha complex; MutSalpha complex binding; mismatch repair; mismatched DNA binding; reciprocal meiotic recombination; single-stranded DNA binding,PF01119;PF00505;,,,,,,,,,PMS1_HUMAN,Homo sapiens (Human),mismatch repair [GO:0006298] comp136807_c0_seq1,2274,40.8531,0.35228623,110,298,,0,P60670,Nuclear protein localization protein 4 homolog (Protein NPL4),Nuclear protein localization protein 4 homolog (Protein NPL4),GO:0030433; GO:0007030; GO:0005829; GO:0005783; GO:0061025; GO:0042175; GO:0005634; GO:0008270,ER-associated protein catabolic process; Golgi organization; cytosol; endoplasmic reticulum; membrane fusion; nuclear outer membrane-endoplasmic reticulum membrane network; nucleus; zinc ion binding,PF05021;PF11543;PF05020;,0,CHOYP_NPL4.1.1,,,,,,,NPL4_MOUSE,Mus musculus (Mouse),"ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; Golgi organization [GO:0007030]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp136807_c0_seq2,737,39.7558,0.4476492,0,9,,,,,,,,,3.00E-21,CHOYP_NPL4.1.1,,,,,,,,, comp136810_c3_seq1,1555,35.4341,0.44370232,374,1781,,2.00E-116,P61210,ADP-ribosylation factor 1 (lARF1),ADP-ribosylation factor 1 (lARF1),GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,2.00E-20,CHOYP_LOC100637317.2.4,3.00E-61,ruditapes_c4018,,,,,ARF1_LOCMI,Locusta migratoria (Migratory locust),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp136810_c3_seq2,1764,32.3696,0.56028918,414,2047,,6.00E-105,O00909,ADP-ribosylation factor 1,ADP-ribosylation factor 1,GO:0005525; GO:0005794; GO:0000281; GO:0048471; GO:0045335; GO:0015031; GO:0051489; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; mitotic cytokinesis; perinuclear region of cytoplasm; phagocytic vesicle; protein transport; regulation of filopodium assembly; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,5.00E-118,CHOYP_ARF2.3.3,8.00E-31,ruditapes2_c1053,,,,,ARF1_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of filopodium assembly [GO:0051489]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp136810_c3_seq3,866,37.4134,0.50666267,547,3628,,7.00E-107,P51644,ADP-ribosylation factor 4,ADP-ribosylation factor 4,GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,5.00E-83,CHOYP_ARF4.1.2,3.00E-14,ruditapes_c25281,,,,,ARF4_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp136810_c4_seq2,896,40.8482,1.12527022,0,0,,2.00E-10,D9HP19,Cell number regulator 3 (ZmCNR03),Cell number regulator 3 (ZmCNR03),GO:0016021,integral to membrane,PF04749;,,,1.00E-24,ruditapes_c7758,,,,,CNR3_MAIZE,Zea mays (Maize), comp136810_c4_seq3,1001,39.2607,1.11708693,0,0,,4.00E-15,P0CW97,Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),GO:0016021,integral to membrane,PF04749;,,,,,,,,,PCR3_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp136810_c4_seq5,950,38.4211,1.17457053,0,0,,3.00E-15,P0CW97,Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),GO:0016021,integral to membrane,PF04749;,,,,,,,,,PCR3_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp136811_c0_seq2,1792,35.9375,0.5472493,28,74,,2.00E-71,Q9UJK0,Ribosome biogenesis protein TSR3 homolog,Ribosome biogenesis protein TSR3 homolog,GO:0006364,rRNA processing,PF04034;PF04068;,2.00E-29,CHOYP_LOC100010388.1.1,,,,,,,TSR3_HUMAN,Homo sapiens (Human),maturation of SSU-rRNA [GO:0030490] comp136815_c2_seq1,1297,40.7093,0.5254532,61,95,,5.00E-14,Q6R7G8,Putative transmembrane protein ORF57,Putative transmembrane protein ORF57,GO:0033644; GO:0016021,host cell membrane; integral to membrane,PF05934;,,,,,,,,,Y057_OSHVF,Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus), comp136817_c0_seq2,1009,43.2111,0.53604652,0,2,,2.00E-72,Q503V9,Poly(U)-specific endoribonuclease-B (EC 3.1.-.-) (Protein endoU-B) (Uridylate-specific endoribonuclease-B),Poly(U)-specific endoribonuclease-B (EC 3.1.-.-) (Protein endoU-B) (Uridylate-specific endoribonuclease-B),GO:0003723; GO:0004521; GO:0046872,RNA binding; endoribonuclease activity; metal ion binding,PF09412;,2.00E-51,CHOYP_LOC100370026.1.1,,,,,,,ENDUB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136821_c1_seq1,1125,44.1778,0.49234047,0,0,,4.00E-60,Q1KKT4,Protein lunapark-A,Protein lunapark-A,GO:0016021,integral to membrane,PF10058;,,,,,,,,,LNPA_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),endoplasmic reticulum tubular network organization [GO:0071786] comp136821_c1_seq2,1143,44.4444,0.49652816,1,0,,4.00E-81,Q9C0E8,Protein lunapark,Protein lunapark,GO:0007596; GO:0042733; GO:0035115; GO:0016021; GO:0060173; GO:0032330,blood coagulation; embryonic digit morphogenesis; embryonic forelimb morphogenesis; integral to membrane; limb development; regulation of chondrocyte differentiation,PF10058;,,,,,,,,,LNP_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; regulation of chondrocyte differentiation [GO:0032330] comp136821_c1_seq3,1125,44.7111,0.49849832,1,0,,3.00E-82,Q7TQ95,Protein lunapark (Protein ulnaless),Protein lunapark (Protein ulnaless),GO:0007596; GO:0042733; GO:0035115; GO:0016021; GO:0032330,blood coagulation; embryonic digit morphogenesis; embryonic forelimb morphogenesis; integral to membrane; regulation of chondrocyte differentiation,PF10058;,,,,,,,,,LNP_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum tubular network organization [GO:0071786]; regulation of chondrocyte differentiation [GO:0032330] comp136821_c1_seq4,1107,44.4444,0.49438168,0,0,,2.00E-18,A8XK26,Protein lunapark-1,Protein lunapark-1,GO:0016021; GO:0032880; GO:0007416; GO:0007268,integral to membrane; regulation of protein localization; synapse assembly; synaptic transmission,PF10058;,6.00E-39,CHOYP_LNP.1.1,,,,,,,LNP1_CAEBR,Caenorhabditis briggsae,chemical synaptic transmission [GO:0007268]; endoplasmic reticulum tubular network organization [GO:0071786]; regulation of protein localization [GO:0032880]; synapse assembly [GO:0007416] comp136825_c0_seq1,2545,41.8075,0.51661762,272,1827,,0,Q61188,Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2),Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2),GO:0035098; GO:0070314; GO:0003723; GO:0070301; GO:0021695; GO:0003682; GO:0005694; GO:0001047; GO:0070734; GO:0042054; GO:0018024; GO:2000134; GO:0045605; GO:0045814; GO:0048387; GO:0051154; GO:0034244; GO:0000122; GO:0043406; GO:0032320; GO:0010718; GO:0045120; GO:0042127; GO:0014013; GO:0043565; GO:0006351,"ESC/E(Z) complex; G1 to G0 transition; RNA binding; cellular response to hydrogen peroxide; cerebellar cortex development; chromatin binding; chromosome; core promoter binding; histone H3-K27 methylation; histone methyltransferase activity; histone-lysine N-methyltransferase activity; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of epidermal cell differentiation; negative regulation of gene expression, epigenetic; negative regulation of retinoic acid receptor signaling pathway; negative regulation of striated muscle cell differentiation; negative regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; positive regulation of MAP kinase activity; positive regulation of Ras GTPase activity; positive regulation of epithelial to mesenchymal transition; pronucleus; regulation of cell proliferation; regulation of gliogenesis; sequence-specific DNA binding; transcription, DNA-dependent",PF11616;PF00856;,1.00E-153,CHOYP_EZH2.1.1,,,,,,,EZH2_MOUSE,Mus musculus (Mouse),"cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to trichostatin A [GO:0035984]; cerebellar cortex development [GO:0021695]; DNA methylation [GO:0006306]; G1 to G0 transition [GO:0070314]; hepatocyte homeostasis [GO:0036333]; hippocampus development [GO:0021766]; histone H3-K27 methylation [GO:0070734]; histone H3-K27 trimethylation [GO:0098532]; histone methylation [GO:0016571]; liver regeneration [GO:0097421]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of striated muscle cell differentiation [GO:0051154]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein localization to chromatin [GO:0071168]; regulation of cell proliferation [GO:0042127]; regulation of circadian rhythm [GO:0042752]; regulation of gene expression [GO:0010468]; regulation of gliogenesis [GO:0014013]; regulation of neurogenesis [GO:0050767]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estradiol [GO:0032355]; response to tetrachloromethane [GO:1904772]; rhythmic process [GO:0048511]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834]; transcription, DNA-templated [GO:0006351]" comp136826_c0_seq1,1367,43.1602,0.99945259,2,191,,5.00E-06,Q1LZB9,Follistatin-related protein 3 (Follistatin-like protein 3),Follistatin-related protein 3 (Follistatin-like protein 3),GO:0005615; GO:0002244; GO:0030514; GO:0032926; GO:0045671; GO:0005634; GO:0001503; GO:0022409; GO:0045944; GO:0006351,"extracellular space; hematopoietic progenitor cell differentiation; negative regulation of BMP signaling pathway; negative regulation of activin receptor signaling pathway; negative regulation of osteoclast differentiation; nucleus; ossification; positive regulation of cell-cell adhesion; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF09289;PF07648;,,,,,,,,,FSTL3_BOVIN,Bos taurus (Bovine),"hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of osteoclast differentiation [GO:0045671]; ossification [GO:0001503]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp136827_c0_seq2,656,41.0061,0.4745011,147,764,,9.00E-75,Q5EAD5,Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta),Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta),GO:0004662; GO:0008152; GO:0046872,CAAX-protein geranylgeranyltransferase activity; metabolic process; metal ion binding,PF00432;,2.00E-47,CHOYP_LOC100378658.1.1,,,,,,,PGTB1_BOVIN,Bos taurus (Bovine),protein geranylgeranylation [GO:0018344] comp136828_c0_seq1,1660,43.012,0.89532584,100,452,,9.00E-74,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,2.00E-21,CHOYP_BRAFLDRAFT_208436.30.32,7.00E-25,ruditapes_c25622,,,,,HS12B_HUMAN,Homo sapiens (Human), comp136828_c0_seq2,450,46.2222,1.0067014,3,24,,,,,,,,,5.00E-16,CHOYP_BRAFLDRAFT_208293.6.20,,,,,,,,, comp136828_c0_seq3,235,43.8298,0.81819663,4,10,,8.00E-14,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp136830_c0_seq1,1415,44.8057,0.42537873,1257,5938,,3.00E-121,Q68EI0,WD repeat-containing protein 18,WD repeat-containing protein 18,GO:0070121; GO:0007368,Kupffer's vesicle development; determination of left/right symmetry,PF00400;PF14077;,,,3.00E-79,ruditapes_c9261,,,,,WDR18_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),determination of left/right symmetry [GO:0007368]; Kupffer's vesicle development [GO:0070121] comp136832_c0_seq1,1900,42.3158,0.42793106,662,1146,,1.00E-167,Q1RLY6,Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase),Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase),GO:0009435; GO:0019674; GO:0016021; GO:0004502; GO:0005741; GO:0019805; GO:0006569,NAD biosynthetic process; NAD metabolic process; integral to membrane; kynurenine 3-monooxygenase activity; mitochondrial outer membrane; quinolinate biosynthetic process; tryptophan catabolic process,PF01494;,1.00E-88,CHOYP_KMO.1.2,,,,,,,KMO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; kynurenine metabolic process [GO:0070189]; NAD metabolic process [GO:0019674]; quinolinate biosynthetic process [GO:0019805]; response to yeast [GO:0001878]; secondary metabolite biosynthetic process [GO:0044550]; tryptophan catabolic process [GO:0006569] comp136833_c0_seq1,1670,37.6647,0.81628362,80,145,,3.00E-06,O05871,Serine/threonine-protein kinase PknD (EC 2.7.11.1),,GO:0005524; GO:0005618; GO:0016036; GO:0005829; GO:0005576; GO:0005887; GO:0030145; GO:0043086; GO:0045717; GO:0032091; GO:0009405; GO:0043085; GO:0004674,ATP binding; cell wall; cellular response to phosphate starvation; cytosol; extracellular region; integral to plasma membrane; manganese ion binding; negative regulation of catalytic activity; negative regulation of fatty acid biosynthetic process; negative regulation of protein binding; pathogenesis; positive regulation of catalytic activity; protein serine/threonine kinase activity,,,,,,,,,,PKND_MYCTU,, comp136834_c0_seq1,1216,43.0099,0.35935771,92,249,,5.00E-45,Q2KI79,Ankyrin repeat family A protein 2,Ankyrin repeat family A protein 2,GO:0005856; GO:0005829; GO:0030169; GO:0016020; GO:0005634,cytoskeleton; cytosol; low-density lipoprotein particle binding; membrane; nucleus,PF00023;PF12796;,,,,,,,,,ANRA2_BOVIN,Bos taurus (Bovine),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp136838_c0_seq1,1250,38.48,1.14631816,105,253,,2.00E-06,Q86JG6,Cln5-like protein 1,Cln5-like protein 1,GO:0016021; GO:0005764; GO:0022008,integral to membrane; lysosome; neurogenesis,PF09451;PF15014;,,,,,,,,,CLN5A_DICDI,Dictyostelium discoideum (Slime mold),neurogenesis [GO:0022008] comp136840_c0_seq3,2734,35.2231,0.56164589,85,0,,0,Q7ZVA6,Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3),Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0051028; GO:0016607; GO:0000184; GO:0000381; GO:0006417,"ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; cytoplasm; mRNA processing; mRNA transport; nuclear speck; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of alternative mRNA splicing, via spliceosome; regulation of translation",PF00270;PF00271;,0,CHOYP_IF4A3.1.1,,,,,,,IF4A3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]" comp136840_c0_seq5,2718,35.2833,0.55110825,265,341,,1.00E-63,Q9SQV1,DEAD-box ATP-dependent RNA helicase 40 (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase 40 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0000184; GO:0005634; GO:0006364; GO:0005773,"ATP binding; ATP-dependent helicase activity; RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; rRNA processing; vacuole",PF00270;PF00271;PF00397;,5.00E-120,CHOYP_EF1A.3.4,6.00E-136,ruditapes2_c2002,,,,,RH40_ARATH,Arabidopsis thaliana (Mouse-ear cress),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]" comp136840_c0_seq7,2727,34.9468,0.59712328,305,897,,0,Q7ZVA6,Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3),Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0051028; GO:0016607; GO:0000184; GO:0000381; GO:0006417,"ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; cytoplasm; mRNA processing; mRNA transport; nuclear speck; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of alternative mRNA splicing, via spliceosome; regulation of translation",PF00270;PF00271;,0,CHOYP_IF4A3.1.1,4.00E-31,ruditapes_c8263,,,,,IF4A3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]" comp136842_c3_seq1,712,50.9831,0.95321044,0,6,,5.00E-20,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp136842_c3_seq2,1260,44.3651,1.00429104,3,556,female>male,6.00E-06,Q5VX71,Sushi domain-containing protein 4,Sushi domain-containing protein 4,GO:0016021,integral to membrane,PF00084;,,,,,,,,,SUSD4_HUMAN,Homo sapiens (Human),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation of complement activation, alternative pathway [GO:0045957]; negative regulation of complement activation, classical pathway [GO:0045959]; regulation of complement activation [GO:0030449]" comp136842_c3_seq3,713,51.7532,0.944724,0,11,,3.00E-23,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp136843_c0_seq1,2154,38.208,0.56097891,158,1086,,1.00E-145,Q5ZIR1,Endophilin-B1 (SH3 domain-containing GRB2-like protein B1),Endophilin-B1 (SH3 domain-containing GRB2-like protein B1),GO:0051084; GO:0000139; GO:0006915; GO:0005504; GO:0042171; GO:0005741; GO:0006654; GO:1900740; GO:0043234,'de novo' posttranslational protein folding; Golgi membrane; apoptotic process; fatty acid binding; lysophosphatidic acid acyltransferase activity; mitochondrial outer membrane; phosphatidic acid biosynthetic process; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; protein complex,PF03114;PF14604;,7.00E-117,CHOYP_SHLB1.2.2,4.00E-131,ruditapes_c18754,,,,,SHLB1_CHICK,Gallus gallus (Chicken),'de novo' posttranslational protein folding [GO:0051084]; apoptotic process [GO:0006915]; autophagic cell death [GO:0048102]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; protein localization to vacuolar membrane [GO:1903778] comp136853_c0_seq1,1606,38.792,0.51410753,57,427,,1.00E-97,Q86WZ6,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136853_c0_seq2,1479,38.1339,0.48525224,38,205,,2.00E-49,Q86TJ5,Zinc finger protein 554,Zinc finger protein 554,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN554_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136854_c0_seq10,1032,42.2481,0.5055649,1,0,,3.00E-33,P30776,Cohesin subunit rad21 (Double-strand-break repair protein rad21) (SCC1 homolog),Cohesin subunit rad21 (Double-strand-break repair protein rad21) (SCC1 homolog),GO:0008608; GO:0051301; GO:0000775; GO:0000794; GO:0000724; GO:0030892; GO:0007064,"attachment of spindle microtubules to kinetochore; cell division; chromosome, centromeric region; condensed nuclear chromosome; double-strand break repair via homologous recombination; mitotic cohesin complex; mitotic sister chromatid cohesion",PF04824;PF04825;,7.00E-101,CHOYP_RAD21.2.2,,,,,,,RAD21_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell division [GO:0051301]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid cohesion [GO:0007064] comp136854_c0_seq3,1965,39.2875,0.48895295,3,11,,3.00E-31,O93310,Double-strand-break repair protein rad21 homolog (SCC1 homolog),Double-strand-break repair protein rad21 homolog (SCC1 homolog),GO:0006281; GO:0006915; GO:0051301; GO:0007059; GO:0000775; GO:0007067; GO:0000228; GO:0071168,"DNA repair; apoptotic process; cell division; chromosome segregation; chromosome, centromeric region; mitosis; nuclear chromosome; protein localization to chromatin",PF04824;PF04825;,8.00E-40,CHOYP_LOC100376067.2.3,,,,,,,RAD21_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168] comp136854_c0_seq5,2380,42.3109,0.46130283,43,38,,3.00E-107,O60216,Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog),Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog),GO:0006915; GO:0051301; GO:0007059; GO:0000775; GO:0008278; GO:0005829; GO:0006302; GO:0007067; GO:0000278; GO:0034991; GO:0005654; GO:0071168; GO:0007131; GO:0006357,"apoptotic process; cell division; chromosome segregation; chromosome, centromeric region; cohesin complex; cytosol; double-strand break repair; mitosis; mitotic cell cycle; nuclear meiotic cohesin complex; nucleoplasm; protein localization to chromatin; reciprocal meiotic recombination; regulation of transcription from RNA polymerase II promoter",PF04824;PF04825;,,,,,,,,,RAD21_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell division [GO:0051301]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]; protein sumoylation [GO:0016925]; reciprocal meiotic recombination [GO:0007131]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sister chromatid cohesion [GO:0007062] comp136854_c0_seq8,1096,42.062,0.52208305,1,0,,4.00E-75,O93310,Double-strand-break repair protein rad21 homolog (SCC1 homolog),Double-strand-break repair protein rad21 homolog (SCC1 homolog),GO:0006281; GO:0006915; GO:0051301; GO:0007059; GO:0000775; GO:0007067; GO:0000228; GO:0071168,"DNA repair; apoptotic process; cell division; chromosome segregation; chromosome, centromeric region; mitosis; nuclear chromosome; protein localization to chromatin",PF04824;PF04825;,7.00E-101,CHOYP_RAD21.2.2,,,,,,,RAD21_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168] comp136856_c3_seq3,412,35.9223,0.3872866,21,181,,,,,,,,,,,3.00E-16,ruditapes_c4549,,,,,,, comp136858_c0_seq2,665,47.8195,0.74536956,8,135,,4.00E-17,Q69ZS8,Kazrin,Kazrin,GO:0001533; GO:0005737; GO:0030057; GO:0031424; GO:0005634,cornified envelope; cytoplasm; desmosome; keratinization; nucleus,PF00536;PF07647;,,,,,,,,,KAZRN_MOUSE,Mus musculus (Mouse),keratinization [GO:0031424] comp136859_c0_seq3,826,39.7094,0.77916074,29,0,,1.00E-07,Q5ZKE7,UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK),UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK),GO:0005524; GO:0004127; GO:0005737; GO:0004550; GO:0009142; GO:0005634; GO:0006221,ATP binding; cytidylate kinase activity; cytoplasm; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; nucleus; pyrimidine nucleotide biosynthetic process,,,,1.00E-23,ruditapes_c21760,,,,,KCY_CHICK,Gallus gallus (Chicken),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine nucleotide biosynthetic process [GO:0006221] comp136863_c0_seq1,2833,36.9573,0.53429799,13,81,,3.00E-48,Q6IFY7,Reticulon-1-A (RTN1.1) (xRTN1) (XRTN1-C.1),Reticulon-1-A (RTN1.1) (xRTN1) (XRTN1-C.1),GO:0005789; GO:0016021; GO:0005634,endoplasmic reticulum membrane; integral to membrane; nucleus,PF02453;,,,,,,,,,RTN1A_XENLA,Xenopus laevis (African clawed frog), comp136863_c0_seq2,2270,36.3436,0.56841326,0,0,,1.00E-44,Q28D16,Reticulon-3,Reticulon-3,GO:0000139; GO:0005789; GO:0016021; GO:0016192,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; vesicle-mediated transport,PF02453;,,,,,,,,,RTN3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),vesicle-mediated transport [GO:0016192] comp136863_c0_seq4,2147,35.7243,0.56222632,1,37,,1.00E-48,Q6IFY7,Reticulon-1-A (RTN1.1) (xRTN1) (XRTN1-C.1),Reticulon-1-A (RTN1.1) (xRTN1) (XRTN1-C.1),GO:0005789; GO:0016021; GO:0005634,endoplasmic reticulum membrane; integral to membrane; nucleus,PF02453;,2.00E-55,CHOYP_LOC655520.2.2,,,,,,,RTN1A_XENLA,Xenopus laevis (African clawed frog), comp136863_c0_seq5,2712,36.5044,0.52690503,18,85,,,,,,,,,2.00E-55,CHOYP_LOC655520.2.2,,,,,,,,, comp136864_c0_seq2,2457,41.5547,0.49403606,0,11,,0,P59015,Vacuolar protein sorting-associated protein 18 homolog,Vacuolar protein sorting-associated protein 18 homolog,GO:0045176; GO:0015721; GO:0008333; GO:0043485; GO:0048069; GO:0006886; GO:0031902; GO:0005765; GO:0060036; GO:0007634; GO:0016192; GO:0008270,apical protein localization; bile acid and bile salt transport; endosome to lysosome transport; endosome to pigment granule transport; eye pigmentation; intracellular protein transport; late endosome membrane; lysosomal membrane; notochord cell vacuolation; optokinetic behavior; vesicle-mediated transport; zinc ion binding,PF00637;PF05131;,,,,,,,,,VPS18_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; pigment granule maturation [GO:0048757]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904] comp136864_c0_seq4,2155,42.9234,0.50785346,2,5,,0,P59015,Vacuolar protein sorting-associated protein 18 homolog,Vacuolar protein sorting-associated protein 18 homolog,GO:0045176; GO:0015721; GO:0008333; GO:0043485; GO:0048069; GO:0006886; GO:0031902; GO:0005765; GO:0060036; GO:0007634; GO:0016192; GO:0008270,apical protein localization; bile acid and bile salt transport; endosome to lysosome transport; endosome to pigment granule transport; eye pigmentation; intracellular protein transport; late endosome membrane; lysosomal membrane; notochord cell vacuolation; optokinetic behavior; vesicle-mediated transport; zinc ion binding,PF00637;PF05131;,0,CHOYP_VPS18.1.1,,,,,,,VPS18_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; pigment granule maturation [GO:0048757]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904] comp136865_c0_seq1,1205,37.0124,0.4613715,338,409,,3.00E-07,Q6PBI8,Transmembrane protein 177,Transmembrane protein 177,GO:0016021,integral to membrane,,,,,,,,,,TM177_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp136866_c0_seq4,1242,37.037,0.949381,0,0,,4.00E-08,P74148,Universal stress protein Sll1388 (USP Sll1388),Universal stress protein Sll1388 (USP Sll1388),GO:0006950,response to stress,PF00582;,,,,,,,,,Y1388_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),response to stress [GO:0006950] comp136866_c0_seq6,769,39.922,1.03737681,0,0,,1.00E-08,P74148,Universal stress protein Sll1388 (USP Sll1388),Universal stress protein Sll1388 (USP Sll1388),GO:0006950,response to stress,PF00582;,5.00E-19,CHOYP_LOC100185549.6.6,,,,,,,Y1388_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),response to stress [GO:0006950] comp136866_c0_seq8,862,41.1833,1.12063519,0,0,,,,,,,,,5.00E-19,CHOYP_LOC100185549.4.6,,,,,,,,, comp136869_c1_seq1,3159,41.817,0.41819326,3,18,,0,Q86VS8,Protein Hook homolog 3 (h-hook3) (hHK3),Protein Hook homolog 3 (h-hook3) (hHK3),GO:0070695; GO:0005794; GO:0051645; GO:0034451; GO:0005801; GO:0031122; GO:0045022; GO:0007032; GO:0008333; GO:0022027; GO:0007040; GO:0005874; GO:0034454; GO:0008017; GO:0050768; GO:0097150; GO:0000242; GO:0071539; GO:0015031,FHF complex; Golgi apparatus; Golgi localization; centriolar satellite; cis-Golgi network; cytoplasmic microtubule organization; early endosome to late endosome transport; endosome organization; endosome to lysosome transport; interkinetic nuclear migration; lysosome organization; microtubule; microtubule anchoring at centrosome; microtubule binding; negative regulation of neurogenesis; neuronal stem cell maintenance; pericentriolar material; protein localization to centrosome; protein transport,PF05622;,,,,,,,,,HOOK3_HUMAN,Homo sapiens (Human),cytoplasmic microtubule organization [GO:0031122]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; Golgi localization [GO:0051645]; interkinetic nuclear migration [GO:0022027]; lysosome organization [GO:0007040]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; protein localization to centrosome [GO:0071539]; protein transport [GO:0015031] comp136869_c1_seq2,2311,40.1125,0.35593194,11,54,,3.00E-88,Q17AF4,Protein hook,Protein hook,GO:0030705; GO:0006897; GO:0005768; GO:0005874; GO:0008017,cytoskeleton-dependent intracellular transport; endocytosis; endosome; microtubule; microtubule binding,PF05622;,,,,,,,,,HOOK_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),cytoskeleton-dependent intracellular transport [GO:0030705]; endocytosis [GO:0006897] comp136869_c1_seq4,3084,41.8936,0.41275927,0,26,,0,Q86VS8,Protein Hook homolog 3 (h-hook3) (hHK3),Protein Hook homolog 3 (h-hook3) (hHK3),GO:0070695; GO:0005794; GO:0051645; GO:0034451; GO:0005801; GO:0031122; GO:0045022; GO:0007032; GO:0008333; GO:0022027; GO:0007040; GO:0005874; GO:0034454; GO:0008017; GO:0050768; GO:0097150; GO:0000242; GO:0071539; GO:0015031,FHF complex; Golgi apparatus; Golgi localization; centriolar satellite; cis-Golgi network; cytoplasmic microtubule organization; early endosome to late endosome transport; endosome organization; endosome to lysosome transport; interkinetic nuclear migration; lysosome organization; microtubule; microtubule anchoring at centrosome; microtubule binding; negative regulation of neurogenesis; neuronal stem cell maintenance; pericentriolar material; protein localization to centrosome; protein transport,PF05622;,1.00E-147,CHOYP_HOOK3.1.1,,,,,,,HOOK3_HUMAN,Homo sapiens (Human),cytoplasmic microtubule organization [GO:0031122]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; Golgi localization [GO:0051645]; interkinetic nuclear migration [GO:0022027]; lysosome organization [GO:0007040]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; protein localization to centrosome [GO:0071539]; protein transport [GO:0015031] comp136869_c1_seq5,2427,41.1619,0.39448572,4,0,,0,B6MFW3,Protein Hook homolog,Protein Hook homolog,GO:0005737; GO:0005874; GO:0015031,cytoplasm; microtubule; protein transport,PF05622;,1.00E-147,CHOYP_HOOK3.1.1,,,,,,,HOOK_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),protein transport [GO:0015031] comp136870_c3_seq10,712,39.3258,1.05689229,0,0,,,,,,,,,3.00E-14,CHOYP_FAXC.1.1,,,,,,,,, comp136870_c3_seq12,1330,40.1504,0.81309626,0,0,,6.00E-56,Q3UMF9,Failed axon connections homolog,Failed axon connections homolog,GO:0016021,integral to membrane,PF17171;PF17172;,,,,,,,,,FAXC_MOUSE,Mus musculus (Mouse), comp136870_c3_seq2,1332,40.1652,0.92735095,0,0,,2.00E-34,Q95RI5,Failed axon connections,Failed axon connections,GO:0007409,axonogenesis,PF17171;PF17172;,,,,,,,,,FAXC_DROME,Drosophila melanogaster (Fruit fly),axonogenesis [GO:0007409]; neurogenesis [GO:0022008]; sensory perception of pain [GO:0019233] comp136870_c3_seq4,1319,40.0303,0.92352145,0,0,,7.00E-56,Q3UMF9,Failed axon connections homolog,Failed axon connections homolog,GO:0016021,integral to membrane,PF17171;PF17172;,6.00E-14,CHOYP_FAXC.1.1,,,,,,,FAXC_MOUSE,Mus musculus (Mouse), comp136870_c3_seq9,1343,40.2829,0.81860511,0,0,,8.00E-54,F7E235,Failed axon connections homolog,Failed axon connections homolog,GO:0016021,integral to membrane,PF17171;PF17172;,,,,,,,,,FAXC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp136871_c0_seq2,1556,37.6607,0.38703851,26,9,,6.00E-78,F7B645,Transmembrane protein 231,Transmembrane protein 231,GO:0036038; GO:0042384; GO:0060170; GO:0016021; GO:0007224,TCTN-B9D complex; cilium assembly; cilium membrane; integral to membrane; smoothened signaling pathway,PF10149;,8.00E-39,CHOYP_BRAFLDRAFT_276659.1.1,2.00E-24,ruditapes_c9182,,,,,TM231_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium assembly [GO:0042384]; smoothened signaling pathway [GO:0007224] comp136873_c1_seq1,963,40.7061,0.6792992,6067,13851,,2.00E-94,Q94360,"Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit)","Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit)",GO:0051539; GO:0008137; GO:0046872; GO:0005739; GO:0048038; GO:0070469,"4 iron, 4 sulfur cluster binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; mitochondrion; quinone binding; respiratory chain",PF01058;,4.00E-65,CHOYP_LOC100875987.2.2,5.00E-94,ruditapes2_c270,,,,,NDUS7_CAEEL,Caenorhabditis elegans, comp136876_c0_seq1,1917,45.2269,0.47001803,128,97,,3.00E-163,Q10569,Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),GO:0003730; GO:0006379; GO:0005847; GO:0006378,mRNA 3'-UTR binding; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation,PF03178;,4.00E-164,CHOYP_CPSF1.1.1,,,,,,,CPSF1_BOVIN,Bos taurus (Bovine),mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp136877_c0_seq1,222,40.0901,0.79644473,58,363,,6.00E-06,P40151,DNA-dependent ATPase MGS1 (Maintenance of genome stability protein 1),DNA-dependent ATPase MGS1 (Maintenance of genome stability protein 1),GO:0005524; GO:0003677; GO:0006281; GO:0033567; GO:0000733; GO:0006952; GO:0008047; GO:0046872; GO:0005634; GO:0006282; GO:0043142; GO:0043130,"ATP binding; DNA binding; DNA repair; DNA replication, Okazaki fragment processing; DNA strand renaturation; defense response; enzyme activator activity; metal ion binding; nucleus; regulation of DNA repair; single-stranded DNA-dependent ATPase activity; ubiquitin binding",PF00004;PF16193;PF12002;,,,,,,,,,WRIP1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA repair [GO:0006281]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA strand renaturation [GO:0000733]; regulation of DNA repair [GO:0006282]" comp136877_c1_seq1,1336,38.2485,0.62216949,95,1181,,3.00E-97,O14003,Replication factor C subunit 3 (Replication factor C3),Replication factor C subunit 3 (Replication factor C3),GO:0005524; GO:0031390; GO:0003677; GO:0000077; GO:0005663; GO:0006261; GO:0031391; GO:0031389; GO:0065007; GO:0005829; GO:0000790; GO:0043596; GO:0017111,ATP binding; Ctf18 RFC-like complex; DNA binding; DNA damage checkpoint; DNA replication factor C complex; DNA-dependent DNA replication; Elg1 RFC-like complex; Rad17 RFC-like complex; biological regulation; cytosol; nuclear chromatin; nuclear replication fork; nucleoside-triphosphatase activity,PF00004;PF08542;,,,,,,,,,RFC3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),DNA strand elongation involved in DNA replication [GO:0006271]; mitotic DNA replication leading strand elongation [GO:1903460]; UV-damage excision repair [GO:0070914] comp136877_c1_seq2,1352,38.3876,0.59083002,284,786,,4.00E-159,Q9D0F6,Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36),Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36),GO:0005524; GO:0003677; GO:0006260; GO:0005663; GO:0017111; GO:0005634,ATP binding; DNA binding; DNA replication; DNA replication factor C complex; nucleoside-triphosphatase activity; nucleus,PF00004;PF08542;,3.00E-120,CHOYP_LOC100373830.1.1,,,4.00E-123,AM858831.p.cg.6,8,,RFC5_MOUSE,Mus musculus (Mouse),DNA-dependent DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] comp136879_c2_seq1,1332,35.8108,0.89060462,58,316,,2.00E-15,Q05187,Hemocyte protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Hemocyte transglutaminase) (TGase),Hemocyte protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Hemocyte transglutaminase) (TGase),GO:0016020; GO:0046872; GO:0018149; GO:0003810,membrane; metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,TGMH_TACTR,Tachypleus tridentatus (Japanese horseshoe crab),peptide cross-linking [GO:0018149] comp136883_c1_seq1,1573,43.0388,0.68781464,0,0,,6.00E-111,Q96AE7,Tetratricopeptide repeat protein 17 (TPR repeat protein 17),Tetratricopeptide repeat protein 17 (TPR repeat protein 17),,,PF13181;,,,,,,,,,TTC17_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] comp136883_c1_seq3,2571,45.352,0.69701285,0,0,,7.00E-113,Q96AE7,Tetratricopeptide repeat protein 17 (TPR repeat protein 17),Tetratricopeptide repeat protein 17 (TPR repeat protein 17),,,PF13181;,1.00E-147,CHOYP_BRAFLDRAFT_231915.1.1,,,,,,,TTC17_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] comp136883_c1_seq4,424,43.8679,0.4928135,0,0,,,,,,,,,,,5.00E-20,ruditapes_c9328,,,,,,, comp136883_c1_seq5,1218,42.4466,0.70978565,6,37,,,,,,,,,2.00E-141,CHOYP_BRAFLDRAFT_231915.1.1,,,,,,,,, comp136884_c0_seq3,1111,39.4239,0.49141454,5,2,,3.00E-66,A3KMZ6,"Cytochrome c oxidase assembly protein COX11, mitochondrial","Cytochrome c oxidase assembly protein COX11, mitochondrial",GO:0005507; GO:0016021; GO:0005743,copper ion binding; integral to membrane; mitochondrial inner membrane,PF04442;,7.00E-25,CHOYP_COX11.1.1,8.00E-29,ruditapes_c21069,,,,,COX11_BOVIN,Bos taurus (Bovine), comp136888_c1_seq1,1877,39.4779,0.3593889,24,58,,5.00E-142,Q5RAU0,Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase),Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase),GO:0003995; GO:0003997; GO:0033540; GO:0050660; GO:0005777,acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; fatty acid beta-oxidation using acyl-CoA oxidase; flavin adenine dinucleotide binding; peroxisome,PF01756;PF00441;PF02770;,7.00E-104,CHOYP_ACOX3.1.1,,,,,,,ACOX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540] comp136888_c1_seq2,1521,37.5411,0.30079807,3,0,,,,,,,,,1.00E-48,CHOYP_ACOX3.1.1,,,,,,,,, comp136890_c0_seq1,2128,37.1241,0.33260435,93,379,,6.00E-77,Q3ZBR5,Tetratricopeptide repeat protein 1 (TPR repeat protein 1),Tetratricopeptide repeat protein 1 (TPR repeat protein 1),GO:0005778,peroxisomal membrane,PF00515;,7.00E-54,CHOYP_TTC1.2.2,,,,,,,TTC1_BOVIN,Bos taurus (Bovine), comp136892_c3_seq13,1404,36.8234,0.9461709,0,21,,,,,,,,,,,7.00E-24,ruditapes_c13395,,,,,,, comp136894_c0_seq1,909,63.6964,0.9598935,0,355,,2.00E-124,P12329,"Chlorophyll a-b binding protein 1, chloroplastic (LHCII type I CAB-1) (LHCP)","Chlorophyll a-b binding protein 1, chloroplastic (LHCII type I CAB-1) (LHCP)",GO:0016168; GO:0009535; GO:0016021; GO:0046872; GO:0009765; GO:0009522; GO:0009523; GO:0018298,"chlorophyll binding; chloroplast thylakoid membrane; integral to membrane; metal ion binding; photosynthesis, light harvesting; photosystem I; photosystem II; protein-chromophore linkage",PF00504;,,,,,,,,,CB21_MAIZE,Zea mays (Maize),"photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]" comp136894_c0_seq2,854,65.1054,0.95299108,0,199,,3.00E-126,P27517,"Chlorophyll a-b binding protein of LHCII type I, chloroplastic (CAB) (LHCP)","Chlorophyll a-b binding protein of LHCII type I, chloroplastic (CAB) (LHCP)",GO:0016168; GO:0009535; GO:0016021; GO:0046872; GO:0009765; GO:0009522; GO:0009523; GO:0018298,"chlorophyll binding; chloroplast thylakoid membrane; integral to membrane; metal ion binding; photosynthesis, light harvesting; photosystem I; photosystem II; protein-chromophore linkage",PF00504;,,,,,,,,,CB2_DUNTE,Dunaliella tertiolecta (Green alga),"photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]" comp136895_c1_seq1,561,37.9679,0.59618294,18,108,,3.00E-10,Q11073,Uncharacterized protein B0416.5,Uncharacterized protein B0416.5,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,YT45_CAEEL,Caenorhabditis elegans,transmembrane transport [GO:0055085] comp136896_c0_seq2,1367,50.695,0.60417011,6,25,,3.00E-96,P25054,Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5),Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5),GO:0033077; GO:0005912; GO:0009952; GO:0009798; GO:0044295; GO:0007409; GO:0030877; GO:0060070; GO:0007155; GO:0007050; GO:0016477; GO:0006921; GO:0005813; GO:0051276; GO:0005881; GO:0031122; GO:0005829; GO:0009953; GO:0001942; GO:0001822; GO:0000776; GO:0030027; GO:0016328; GO:0007091; GO:0035371; GO:0051010; GO:0000281; GO:0007094; GO:0046716; GO:0043409; GO:0043066; GO:0090090; GO:0008285; GO:0045736; GO:0060770; GO:0007026; GO:0042483; GO:0005634; GO:0043065; GO:0045785; GO:0051781; GO:0030335; GO:0030858; GO:0031116; GO:0045732; GO:0031274; GO:0006461; GO:0019887; GO:0009954; GO:0051988; GO:0051171; GO:0045667; GO:0045670; GO:0006974; GO:0060041; GO:0032587; GO:0035019; GO:0048538; GO:0005923; GO:0070830,T cell differentiation in thymus; adherens junction; anterior/posterior pattern specification; axis specification; axonal growth cone; axonogenesis; beta-catenin destruction complex; canonical Wnt receptor signaling pathway; cell adhesion; cell cycle arrest; cell migration; cellular component disassembly involved in execution phase of apoptosis; centrosome; chromosome organization; cytoplasmic microtubule; cytoplasmic microtubule organization; cytosol; dorsal/ventral pattern formation; hair follicle development; kidney development; kinetochore; lamellipodium; lateral plasma membrane; metaphase/anaphase transition of mitotic cell cycle; microtubule plus end; microtubule plus-end binding; mitotic cytokinesis; mitotic spindle assembly checkpoint; muscle cell cellular homeostasis; negative regulation of MAPK cascade; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of epithelial cell proliferation involved in prostate gland development; negative regulation of microtubule depolymerization; negative regulation of odontogenesis; nucleus; positive regulation of apoptotic process; positive regulation of cell adhesion; positive regulation of cell division; positive regulation of cell migration; positive regulation of epithelial cell differentiation; positive regulation of microtubule polymerization; positive regulation of protein catabolic process; positive regulation of pseudopodium assembly; protein complex assembly; protein kinase regulator activity; proximal/distal pattern formation; regulation of attachment of spindle microtubules to kinetochore; regulation of nitrogen compound metabolic process; regulation of osteoblast differentiation; regulation of osteoclast differentiation; response to DNA damage stimulus; retina development in camera-type eye; ruffle membrane; somatic stem cell maintenance; thymus development; tight junction; tight junction assembly,PF05972;PF05956;PF05923;PF16689;PF00514;PF05937;PF05924;,7.00E-109,CHOYP_APC.1.2,,,,,,,APC_HUMAN,Homo sapiens (Human),beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; canonical Wnt signaling pathway [GO:0060070]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment or maintenance of cell polarity [GO:0007163]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of glutamate metabolic process [GO:2000211]; regulation of microtubule-based process [GO:0032886]; response to alcohol [GO:0097305]; response to drug [GO:0042493]; Wnt signaling pathway [GO:0016055] comp136898_c0_seq3,1291,47.9473,0.4347975,14,0,,,,,,,,,6.00E-52,CHOYP_BRAFLDRAFT_125670.1.1,,,,,,,,, comp136898_c1_seq1,417,49.4005,0.55348848,76,0,,9.00E-10,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp136899_c0_seq1,723,37.7593,0.19716813,2,0,,,,,,,,,5.00E-31,CHOYP_BRAFLDRAFT_202836.1.1,,,,,,,,, comp136899_c0_seq2,1206,39.7181,0.50912194,61,70,,2.00E-45,Q9H0I2,Enkurin domain-containing protein 1,Enkurin domain-containing protein 1,GO:0005881,cytoplasmic microtubule,PF13864;,,,,,,,,,CP048_HUMAN,Homo sapiens (Human), comp136901_c0_seq1,802,43.6409,0.62961972,774,3020,,5.00E-78,Q7ZYA2,Transcription initiation factor TFIID subunit 8 (TBP-associated factor 8),Transcription initiation factor TFIID subunit 8 (TBP-associated factor 8),GO:0030154; GO:0005737; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"cell differentiation; cytoplasm; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07524;PF10406;,6.00E-50,CHOYP_BRAFLDRAFT_214741.1.1,,,,,,,TAF8_XENLA,Xenopus laevis (African clawed frog),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136907_c0_seq1,1632,40.625,0.4166729,285,802,,,,,,,,,1.00E-74,CHOYP_BRAFLDRAFT_125516.1.1,,,,,,,,, comp136908_c3_seq3,2143,38.4041,0.54648747,0,0,,1.00E-14,P55821,Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10),Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10),GO:0005794; GO:0030424; GO:0005768; GO:0030426; GO:0016020; GO:0048471; GO:0031110; GO:0031982,Golgi apparatus; axon; endosome; growth cone; membrane; perinuclear region of cytoplasm; regulation of microtubule polymerization or depolymerization; vesicle,PF00836;,,,,,,,,,STMN2_MOUSE,Mus musculus (Mouse),cellular response to nerve growth factor stimulus [GO:1990090]; microtubule depolymerization [GO:0007019]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of neuron projection development [GO:0010977]; neuron projection development [GO:0031175]; positive regulation of microtubule depolymerization [GO:0031117]; positive regulation of neuron projection development [GO:0010976]; regulation of cytoskeleton organization [GO:0051493] comp136908_c3_seq4,2250,39.0667,0.58205289,0,0,,8.00E-19,P13668,Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Pr22 protein) (Prosolin) (pp17),Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Pr22 protein) (Prosolin) (pp17),GO:0007420; GO:0030154; GO:0005737; GO:0035556; GO:0005874; GO:0007019; GO:0031110,brain development; cell differentiation; cytoplasm; intracellular signal transduction; microtubule; microtubule depolymerization; regulation of microtubule polymerization or depolymerization,PF00836;,,,,,,,,,STMN1_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; brain development [GO:0007420]; intracellular signal transduction [GO:0035556]; microtubule depolymerization [GO:0007019]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule polymerization [GO:0031115]; neuron projection development [GO:0031175]; positive regulation of cellular component movement [GO:0051272]; regulation of cytoskeleton organization [GO:0051493]; response to virus [GO:0009615] comp136912_c2_seq1,1513,33.9722,0.43968593,101,686,,5.00E-24,O43829,Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5),Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5),GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF00651;PF00096;,1.00E-16,CHOYP_ZN468.1.1,,,,,,,ZF161_HUMAN,Homo sapiens (Human),"cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart valve development [GO:0003170]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp136913_c0_seq1,267,42.3221,0.17092076,17,11,,,,,,,,,9.00E-23,CHOYP_C2D1.1.1,,,,,,,,, comp136913_c0_seq2,1709,48.4494,0.28937228,1,0,,6.00E-32,Q5T0F9,Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2),Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2),GO:0000978; GO:0001078; GO:0005634,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; nucleus,PF00168;,,,,,,,,,C2D1B_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp136913_c0_seq3,1703,48.5026,0.26986073,8,7,,3.00E-39,Q6P1N0,Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N),Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N),GO:0000978; GO:0001078; GO:0005737; GO:0005815; GO:0005634; GO:0043123; GO:0004871,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cytoplasm; microtubule organizing center; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity,PF00168;,,,,,,,,,C2D1A_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transcription, DNA-templated [GO:0006351]" comp136918_c0_seq2,816,43.1373,0.43938085,9,82,,2.00E-70,Q8BZB2,Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC),Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC),GO:0015937; GO:0004633,coenzyme A biosynthetic process; phosphopantothenoylcysteine decarboxylase activity,PF02441;,7.00E-36,CHOYP_PPCDC.1.1,,,,,,,COAC_MOUSE,Mus musculus (Mouse),coenzyme A biosynthetic process [GO:0015937] comp136921_c0_seq11,1202,39.8502,0.78064876,10,1970,female>male,2.00E-12,P51910,Apolipoprotein D (Apo-D) (ApoD),Apolipoprotein D (Apo-D) (ApoD),GO:0007568; GO:0007420; GO:0015485; GO:0022626; GO:0030425; GO:0005783; GO:0005615; GO:0006006; GO:0006629; GO:2000405; GO:1900016; GO:0051895; GO:0060588; GO:0071638; GO:0010642; GO:0042308; GO:0048662; GO:2000098; GO:0043025; GO:0048471; GO:0014012; GO:0042493; GO:0000302; GO:0042246; GO:0005215,aging; brain development; cholesterol binding; cytosolic ribosome; dendrite; endoplasmic reticulum; extracellular space; glucose metabolic process; lipid metabolic process; negative regulation of T cell migration; negative regulation of cytokine production involved in inflammatory response; negative regulation of focal adhesion assembly; negative regulation of lipoprotein lipid oxidation; negative regulation of monocyte chemotactic protein-1 production; negative regulation of platelet-derived growth factor receptor signaling pathway; negative regulation of protein import into nucleus; negative regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell-matrix adhesion; neuronal cell body; perinuclear region of cytoplasm; peripheral nervous system axon regeneration; response to drug; response to reactive oxygen species; tissue regeneration; transporter activity,PF08212;,3.00E-30,CHOYP_APOD.1.1,,,,,,,APOD_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246] comp136921_c0_seq13,1898,43.7302,0.55787325,5,29,,2.00E-11,P56273,E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Xdm2) (p53-binding protein Mdm2),E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Xdm2) (p53-binding protein Mdm2),GO:0005737; GO:0016874; GO:0043066; GO:0071157; GO:0000122; GO:0005730; GO:0005654; GO:0016567; GO:0008270,cytoplasm; ligase activity; negative regulation of apoptotic process; negative regulation of cell cycle arrest; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; protein ubiquitination; zinc ion binding,PF02201;PF00641;,,,,,,,,,MDM2_XENLA,Xenopus laevis (African clawed frog),negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567] comp136921_c0_seq23,1897,43.7006,0.56034498,0,0,,2.00E-11,P56273,E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Xdm2) (p53-binding protein Mdm2),E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Xdm2) (p53-binding protein Mdm2),GO:0005737; GO:0016874; GO:0043066; GO:0071157; GO:0000122; GO:0005730; GO:0005654; GO:0016567; GO:0008270,cytoplasm; ligase activity; negative regulation of apoptotic process; negative regulation of cell cycle arrest; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; protein ubiquitination; zinc ion binding,PF02201;PF00641;,,,,,,,,,MDM2_XENLA,Xenopus laevis (African clawed frog),negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567] comp136921_c0_seq26,264,34.4697,0.6438382,3,22,,3.00E-11,Q60524,E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Oncoprotein Mdm2) (p53-binding protein Mdm2) (Fragment),E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Oncoprotein Mdm2) (p53-binding protein Mdm2) (Fragment),GO:0005737; GO:0016874; GO:0043066; GO:0071157; GO:0000122; GO:0005730; GO:0005654; GO:0016567; GO:0008270,cytoplasm; ligase activity; negative regulation of apoptotic process; negative regulation of cell cycle arrest; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; protein ubiquitination; zinc ion binding,PF02201;PF00641;,,,,,,,,,MDM2_MESAU,Mesocricetus auratus (Golden hamster),"negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]" comp136921_c0_seq9,265,34.717,0.64815738,0,8,,4.00E-10,P56951,E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Edm2) (p53-binding protein Mdm2),E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Edm2) (p53-binding protein Mdm2),GO:0005737; GO:0016874; GO:0043066; GO:0071157; GO:0000122; GO:0005730; GO:0005654; GO:0016567; GO:0008270,cytoplasm; ligase activity; negative regulation of apoptotic process; negative regulation of cell cycle arrest; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; protein ubiquitination; zinc ion binding,PF02201;PF00641;,,,,,,,,,MDM2_HORSE,Equus caballus (Horse),"negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]" comp136922_c0_seq1,1322,43.7216,0.69311784,217,154,,3.00E-88,Q9JI85,Nucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into: Nesfatin-1],Nucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into: Nesfatin-1],GO:0003677; GO:0005797; GO:0005509; GO:0005783; GO:0005576; GO:0016020; GO:0005635,DNA binding; Golgi medial cisterna; calcium ion binding; endoplasmic reticulum; extracellular region; membrane; nuclear envelope,PF13499;,2.00E-84,CHOYP_NUCB2.1.2,8.00E-17,ruditapes_c13882,,,,,NUCB2_RAT,Rattus norvegicus (Rat),insulin metabolic process [GO:1901142]; negative regulation of appetite [GO:0032099]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucagon secretion [GO:0070093]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of testosterone secretion [GO:2000845]; response to glucose [GO:0009749]; response to human chorionic gonadotropin [GO:0044752]; response to melanocyte-stimulating hormone [GO:1990680]; response to starvation [GO:0042594] comp136927_c0_seq1,626,40.8946,0.54051862,28,235,,5.00E-41,Q8AVR4,Programmed cell death protein 10,Programmed cell death protein 10,GO:0000139; GO:0001525; GO:0006915; GO:0005886,Golgi membrane; angiogenesis; apoptotic process; plasma membrane,,2.00E-105,CHOYP_AGAP_AGAP008287.1.1,,,,,,,PDC10_XENLA,Xenopus laevis (African clawed frog),angiogenesis [GO:0001525]; apoptotic process [GO:0006915] comp136927_c2_seq2,822,41.1192,0.3746154,29,43,,5.00E-07,O01971,Emerin homolog 1 (Ce-emerin),Emerin homolog 1 (Ce-emerin),GO:0007059; GO:0005639; GO:0000281; GO:0010165,chromosome segregation; integral to nuclear inner membrane; mitotic cytokinesis; response to X-ray,PF03020;,,,,,,,,,EMR1_CAEEL,Caenorhabditis elegans,chromosome segregation [GO:0007059]; mitotic cytokinesis [GO:0000281]; response to X-ray [GO:0010165] comp136928_c0_seq1,1457,40.7001,0.96362687,135,839,,9.00E-10,Q5ZLN0,Leucine-rich repeat-containing protein 40,Leucine-rich repeat-containing protein 40,,,PF13855;,,,1.00E-21,ruditapes_c14192,,,,,LRC40_CHICK,Gallus gallus (Chicken), comp136932_c0_seq1,1473,43.2451,0.4506936,0,0,,1.00E-117,F1M386,Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),GO:0005096; GO:0030165; GO:0017034; GO:0032486; GO:0050699; GO:0071880; GO:0031697; GO:0001568; GO:0031547; GO:0030552; GO:0019933; GO:0005911; GO:0071320; GO:0071321; GO:0061028; GO:0021884; GO:0005770; GO:0008285; GO:0050774; GO:0048022; GO:0038180; GO:0001764; GO:0043005; GO:0031175; GO:0043025; GO:0007218; GO:0048471; GO:0005886; GO:0070374; GO:0032854; GO:2000481; GO:0043950; GO:2000670; GO:2001224; GO:0010976; GO:0032092; GO:2001214; GO:0043234; GO:1901888; GO:0048167; GO:0045202; GO:0021591,GTPase activator activity; PDZ domain binding; Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; WW domain binding; adenylate cyclase-activating adrenergic receptor signaling pathway; beta-1 adrenergic receptor binding; blood vessel development; brain-derived neurotrophic factor receptor signaling pathway; cAMP binding; cAMP-mediated signaling; cell-cell junction; cellular response to cAMP; cellular response to cGMP; establishment of endothelial barrier; forebrain neuron development; late endosome; negative regulation of cell proliferation; negative regulation of dendrite morphogenesis; negative regulation of melanin biosynthetic process; nerve growth factor signaling pathway; neuron migration; neuron projection; neuron projection development; neuronal cell body; neuropeptide signaling pathway; perinuclear region of cytoplasm; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of Rap GTPase activity; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cAMP-mediated signaling; positive regulation of dendritic cell apoptotic process; positive regulation of neuron migration; positive regulation of neuron projection development; positive regulation of protein binding; positive regulation of vasculogenesis; protein complex; regulation of cell junction assembly; regulation of synaptic plasticity; synapse; ventricular system development,PF00595;PF00788;PF00617;PF00618;,,,,,,,,,RPGF2_RAT,Rattus norvegicus (Rat),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591] comp136932_c0_seq2,1679,42.9422,0.50649369,0,24,,1.00E-08,Q9Z1C8,Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI),Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI),GO:0017034; GO:0032486; GO:0001525; GO:0030552; GO:0005952; GO:0008603; GO:0071320; GO:0005737; GO:0061028; GO:0016020; GO:0032854; GO:0045766; GO:0051496; GO:2000249,Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; angiogenesis; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; cellular response to cAMP; cytoplasm; establishment of endothelial barrier; membrane; positive regulation of Rap GTPase activity; positive regulation of angiogenesis; positive regulation of stress fiber assembly; regulation of actin cytoskeleton reorganization,PF00027;PF00610;PF00617;PF00618;,1.00E-56,CHOYP_BRAFLDRAFT_131151.4.4,,,,,,,RPGF3_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; artery development [GO:0060840]; brain development [GO:0007420]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to L-dopa [GO:1904474]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dorsal root ganglion development [GO:1990791]; establishment of endothelial barrier [GO:0061028]; liver regeneration [GO:0097421]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of collagen biosynthetic process [GO:0032966]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcium ion transmembrane transport [GO:1904427]; positive regulation of cell size [GO:0045793]; positive regulation of GTPase activity [GO:0043547]; positive regulation of GTP binding [GO:1904426]; positive regulation of hydrogen:potassium-exchanging ATPase activity [GO:1904453]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; Rap protein signal transduction [GO:0032486]; regulation of actin cytoskeleton reorganization [GO:2000249]; response to nicotine [GO:0035094]; spinal cord development [GO:0021510] comp136932_c0_seq3,1652,43.0993,0.5106218,2,11,,5.00E-153,F1M386,Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1),GO:0005096; GO:0030165; GO:0017034; GO:0032486; GO:0050699; GO:0071880; GO:0031697; GO:0001568; GO:0031547; GO:0030552; GO:0019933; GO:0005911; GO:0071320; GO:0071321; GO:0061028; GO:0021884; GO:0005770; GO:0008285; GO:0050774; GO:0048022; GO:0038180; GO:0001764; GO:0043005; GO:0031175; GO:0043025; GO:0007218; GO:0048471; GO:0005886; GO:0070374; GO:0032854; GO:2000481; GO:0043950; GO:2000670; GO:2001224; GO:0010976; GO:0032092; GO:2001214; GO:0043234; GO:1901888; GO:0048167; GO:0045202; GO:0021591,GTPase activator activity; PDZ domain binding; Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; WW domain binding; adenylate cyclase-activating adrenergic receptor signaling pathway; beta-1 adrenergic receptor binding; blood vessel development; brain-derived neurotrophic factor receptor signaling pathway; cAMP binding; cAMP-mediated signaling; cell-cell junction; cellular response to cAMP; cellular response to cGMP; establishment of endothelial barrier; forebrain neuron development; late endosome; negative regulation of cell proliferation; negative regulation of dendrite morphogenesis; negative regulation of melanin biosynthetic process; nerve growth factor signaling pathway; neuron migration; neuron projection; neuron projection development; neuronal cell body; neuropeptide signaling pathway; perinuclear region of cytoplasm; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of Rap GTPase activity; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cAMP-mediated signaling; positive regulation of dendritic cell apoptotic process; positive regulation of neuron migration; positive regulation of neuron projection development; positive regulation of protein binding; positive regulation of vasculogenesis; protein complex; regulation of cell junction assembly; regulation of synaptic plasticity; synapse; ventricular system development,PF00595;PF00788;PF00617;PF00618;,4.00E-24,CHOYP_BRAFLDRAFT_131151.2.4,,,,,,,RPGF2_RAT,Rattus norvegicus (Rat),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591] comp136932_c0_seq4,1133,47.3963,0.70240496,25,34,,4.00E-10,Q9EQZ6,Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII),Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII),GO:0005088; GO:0030552; GO:0005952; GO:0008603; GO:0019933; GO:0017156; GO:0005829; GO:0030073; GO:0016020; GO:0017157; GO:0051056; GO:0007264,Ras guanyl-nucleotide exchange factor activity; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; cAMP-mediated signaling; calcium ion-dependent exocytosis; cytosol; insulin secretion; membrane; regulation of exocytosis; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00027;PF00610;PF00617;PF00618;,8.00E-63,CHOYP_BRAFLDRAFT_131151.2.4,,,,,,,RPGF4_MOUSE,Mus musculus (Mouse),calcium ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; regulation of exocytosis [GO:0017157]; small GTPase mediated signal transduction [GO:0007264] comp136932_c0_seq5,760,46.7105,0.70113859,0,0,,,,,,,,,2.00E-80,CHOYP_BRAFLDRAFT_131151.4.4,,,,,,,,, comp136932_c0_seq7,1500,43.2,0.45798869,0,0,,1.00E-12,Q80VW5,Whirlin,Whirlin,GO:0005884; GO:0005929; GO:0005737; GO:0030426; GO:0060122; GO:0001895; GO:0050953; GO:0007605; GO:0002142; GO:0032420,actin filament; cilium; cytoplasm; growth cone; inner ear receptor stereocilium organization; retina homeostasis; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; stereocilium,PF00595;,,,,,,,,,WHRN_MOUSE,Mus musculus (Mouse),cerebellar Purkinje cell layer formation [GO:0021694]; establishment of protein localization [GO:0045184]; inner ear receptor stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] comp136939_c0_seq1,2095,41.9093,0.83765174,1080,8334,,2.00E-91,Q9BXW7,Cat eye syndrome critical region protein 5,Cat eye syndrome critical region protein 5,GO:0005739,mitochondrion,PF13344;,1.00E-76,CHOYP_LOC100183583.1.2,2.00E-78,ruditapes_c14079,,,,,CECR5_HUMAN,Homo sapiens (Human),glycerophospholipid biosynthetic process [GO:0046474] comp136945_c0_seq1,1436,38.9276,0.52839542,133,796,,4.00E-64,Q8BGC0,HIV Tat-specific factor 1 homolog,HIV Tat-specific factor 1 homolog,GO:0003723; GO:0000166; GO:0005634; GO:0006355; GO:0006351,"RNA binding; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00076;,7.00E-39,CHOYP_LOC100696985.1.1,,,,,,,HTSF1_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp136947_c0_seq1,1106,40.7776,0.49409657,46,256,,9.00E-66,Q1LXS2,Proteasome assembly chaperone 2 (Tumor necrosis factor superfamily member 5-induced protein 1 homolog),Proteasome assembly chaperone 2 (Tumor necrosis factor superfamily member 5-induced protein 1 homolog),GO:0005634; GO:0043248,nucleus; proteasome assembly,PF09754;,7.00E-25,CHOYP_PSMG2.1.1,,,,,,,PSMG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),proteasome assembly [GO:0043248] comp136953_c0_seq1,741,44.3995,0.25335808,7,52,,1.00E-48,Q9NZJ0,Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein),Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein),GO:0031464; GO:0031465; GO:0006260; GO:0031572; GO:0005813; GO:0005694; GO:0005737; GO:0031965; GO:0005634; GO:0006513; GO:0000209; GO:0051726; GO:0009411; GO:0019985; GO:0006511,Cul4A-RING ubiquitin ligase complex; Cul4B-RING ubiquitin ligase complex; DNA replication; G2 DNA damage checkpoint; centrosome; chromosome; cytoplasm; nuclear membrane; nucleus; protein monoubiquitination; protein polyubiquitination; regulation of cell cycle; response to UV; translesion synthesis; ubiquitin-dependent protein catabolic process,PF00400;,,,,,,,,,DTL_HUMAN,Homo sapiens (Human),"cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; G2 DNA damage checkpoint [GO:0031572]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; regulation of cell cycle [GO:0051726]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp136953_c1_seq1,550,44.3636,0.48206634,20,93,,2.00E-30,Q24371,Protein lethal(2)denticleless (Protein DTL83),Protein lethal(2)denticleless (Protein DTL83),GO:0007049; GO:0005737; GO:0022008; GO:0016567; GO:0051726; GO:0006950,cell cycle; cytoplasm; neurogenesis; protein ubiquitination; regulation of cell cycle; response to stress,PF00400;,,,,,,,,,L2DTL_DROME,Drosophila melanogaster (Fruit fly),cell cycle [GO:0007049]; neurogenesis [GO:0022008]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726] comp136962_c1_seq1,1052,33.6502,0.31084389,649,5231,,5.00E-48,Q28034,Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) (Vacuolar system-associated protein 60) (VASAP-60),Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) (Vacuolar system-associated protein 60) (VASAP-60),GO:0006491; GO:0003723; GO:0005509; GO:0005783; GO:0016787; GO:0001701; GO:0001889; GO:0010977; GO:0006807; GO:0072001,N-glycan processing; RNA binding; calcium ion binding; endoplasmic reticulum; hydrolase activity; in utero embryonic development; liver development; negative regulation of neuron projection development; nitrogen compound metabolic process; renal system development,PF13202;PF12999;PF13015;,5.00E-27,CHOYP_RS32.1.1,2.00E-61,ruditapes_c8518,,,,,GLU2B_BOVIN,Bos taurus (Bovine),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; negative regulation of neuron projection development [GO:0010977]; N-glycan processing [GO:0006491]; nitrogen compound metabolic process [GO:0006807]; renal system development [GO:0072001] comp136963_c0_seq1,1129,37.2011,0.56887916,575,6606,,2.00E-41,Q5JGM7,Intracellular protease 1 (EC 3.2.-.-) (Intracellular protease I),Intracellular protease 1 (EC 3.2.-.-) (Intracellular protease I),GO:0005737; GO:0016798; GO:0008233; GO:0006508,"cytoplasm; hydrolase activity, acting on glycosyl bonds; peptidase activity; proteolysis",PF01965;,,,1.00E-69,ruditapes2_c344,,,,,PFPI_PYRKO,Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)), comp136965_c0_seq1,1424,39.6067,0.3481869,59,337,,1.00E-109,Q6INM2,N-lysine methyltransferase setd6 (EC 2.1.1.-) (SET domain-containing protein 6),N-lysine methyltransferase setd6 (EC 2.1.1.-) (SET domain-containing protein 6),GO:0032088; GO:0005634; GO:0018026; GO:0016279; GO:0050727,negative regulation of NF-kappaB transcription factor activity; nucleus; peptidyl-lysine monomethylation; protein-lysine N-methyltransferase activity; regulation of inflammatory response,PF09273;PF00856;,,,,,,,,,SETD6_XENLA,Xenopus laevis (African clawed frog),negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727] comp136965_c0_seq2,1134,40.8289,0.28492279,0,5,,2.00E-91,E1BI64,N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6),N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6),GO:0032088; GO:0005634; GO:0018026; GO:0016279; GO:0050727,negative regulation of NF-kappaB transcription factor activity; nucleus; peptidyl-lysine monomethylation; protein-lysine N-methyltransferase activity; regulation of inflammatory response,PF09273;PF00856;,7.00E-32,CHOYP_SETD6.1.1,,,,,,,SETD6_BOVIN,Bos taurus (Bovine),histone lysine methylation [GO:0034968]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] comp136966_c1_seq1,837,41.6965,0.30454649,0,3,,,,,,,,,1.00E-59,CHOYP_UTP20.2.4,,,,,,,,, comp136966_c1_seq2,5975,40.7364,0.32105436,47,48,,1.00E-172,Q5XG71,Small subunit processome component 20 homolog (Down-regulated in metastasis protein),Small subunit processome component 20 homolog (Down-regulated in metastasis protein),GO:0005730; GO:0006364,nucleolus; rRNA processing,PF07539;,6.00E-16,CHOYP_UTP20.1.4,,,,,,,UTP20_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]" comp136966_c1_seq4,4973,40.8405,0.31084466,0,0,,6.00E-175,Q5XG71,Small subunit processome component 20 homolog (Down-regulated in metastasis protein),Small subunit processome component 20 homolog (Down-regulated in metastasis protein),GO:0005730; GO:0006364,nucleolus; rRNA processing,PF07539;,5.00E-60,CHOYP_UTP20.2.4,,,,,,,UTP20_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]" comp136966_c1_seq5,3847,41.8768,0.3278577,0,0,,1.00E-164,Q5XG71,Small subunit processome component 20 homolog (Down-regulated in metastasis protein),Small subunit processome component 20 homolog (Down-regulated in metastasis protein),GO:0005730; GO:0006364,nucleolus; rRNA processing,PF07539;,4.00E-60,CHOYP_UTP20.2.4,,,,,,,UTP20_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]" comp136970_c0_seq2,2621,40.4807,0.35901765,189,1557,,0,Q03701,CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor),CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor),GO:0003677; GO:0005634; GO:0006355; GO:0006366,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF03914;,9.00E-79,CHOYP_CEBPZ.1.1,,,,,,,CEBPZ_HUMAN,Homo sapiens (Human),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp136971_c0_seq3,853,31.5358,0.47213687,0,0,,5.00E-06,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp136975_c1_seq1,2333,41.3631,0.63253703,1,5,,6.00E-59,Q8VBV4,F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10),F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10),GO:0005794; GO:0007219; GO:0019005; GO:0031146; GO:0005783; GO:0030324; GO:0005634; GO:0048471; GO:0016567; GO:0003700; GO:0001570,Golgi apparatus; Notch signaling pathway; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; endoplasmic reticulum; lung development; nucleus; perinuclear region of cytoplasm; protein ubiquitination; sequence-specific DNA binding transcription factor activity; vasculogenesis,PF12937;PF00400;,0,CHOYP_BTRC.1.1,,,,,,,FBXW7_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lung development [GO:0030324]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of mitophagy [GO:1903146]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] comp136975_c1_seq2,2319,41.4403,0.62385397,12,5,,3.00E-52,P87053,F-box/WD repeat-containing protein pof1 (Skp1-binding protein 1),F-box/WD repeat-containing protein pof1 (Skp1-binding protein 1),GO:0019005; GO:0071276; GO:0005634; GO:0042787; GO:0007346,SCF ubiquitin ligase complex; cellular response to cadmium ion; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of mitotic cell cycle,PF12937;PF00400;,0,CHOYP_BTRC.1.1,,,,,,,POF1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular response to cadmium ion [GO:0071276]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp136975_c1_seq3,2305,41.6052,0.62272465,9,13,,0,Q9Y297,F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit),F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit),GO:0019005; GO:0016055; GO:0031145; GO:0060444; GO:0071407; GO:0005829; GO:0016874; GO:0033598; GO:0019048; GO:0043433; GO:0045879; GO:0045892; GO:0005634; GO:0042753; GO:0045862; GO:0045893; GO:0051437; GO:0006470; GO:0031648; GO:0000209; GO:0016567; GO:0043122; GO:0051726; GO:0061136; GO:0007165; GO:0016032,"SCF ubiquitin ligase complex; Wnt receptor signaling pathway; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; branching involved in mammary gland duct morphogenesis; cellular response to organic cyclic compound; cytosol; ligase activity; mammary gland epithelial cell proliferation; modulation by virus of host morphology or physiology; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of smoothened signaling pathway; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of circadian rhythm; positive regulation of proteolysis; positive regulation of transcription, DNA-dependent; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein dephosphorylation; protein destabilization; protein polyubiquitination; protein ubiquitination; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of cell cycle; regulation of proteasomal protein catabolic process; signal transduction; viral process",PF12125;PF12937;PF00400;,,,,,,,,,FBW1A_HUMAN,Homo sapiens (Human),"branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp136976_c0_seq1,1069,40.4116,0.44609188,38,336,,6.00E-70,O14618,Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone),Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone),GO:0005375; GO:0005829; GO:0015680; GO:0005743; GO:0005634; GO:0051353; GO:0019430; GO:0004784; GO:0016532; GO:0008270,copper ion transmembrane transporter activity; cytosol; intracellular copper ion transport; mitochondrial inner membrane; nucleus; positive regulation of oxidoreductase activity; removal of superoxide radicals; superoxide dismutase activity; superoxide dismutase copper chaperone activity; zinc ion binding,PF00403;PF00080;,,,,,,,,,CCS_HUMAN,Homo sapiens (Human),intracellular copper ion transport [GO:0015680]; positive regulation of oxidoreductase activity [GO:0051353]; removal of superoxide radicals [GO:0019430]; response to reactive oxygen species [GO:0000302]; superoxide metabolic process [GO:0006801] comp136978_c1_seq1,1412,42.9887,0.43419688,52,339,,6.00E-64,Q09621,Beta-lactamase domain-containing protein 2,Beta-lactamase domain-containing protein 2,GO:0016021,integral to membrane,PF00144;,8.00E-26,CHOYP_LOC575771.2.3,,,,,,,LACT2_CAEEL,Caenorhabditis elegans, comp136979_c0_seq1,2845,38.2074,0.43226605,1664,170,,0,Q96M32,Adenylate kinase 7 (AK 7) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 7),Adenylate kinase 7 (AK 7) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 7),GO:0005524; GO:0004017; GO:0007420; GO:0035083; GO:0004127; GO:0005829; GO:0003351; GO:0002437; GO:0004550; GO:0009142; GO:0007283,ATP binding; adenylate kinase activity; brain development; cilium axoneme assembly; cytidylate kinase activity; cytosol; epithelial cilium movement; inflammatory response to antigenic stimulus; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; spermatogenesis,PF05186;,0,CHOYP_LOC100369935.1.1,8.00E-40,ruditapes_c12428,,,,,KAD7_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp136981_c1_seq1,4159,44.0731,0.46592875,0,0,,7.00E-79,Q8IN94,Trithorax group protein osa (Protein eyelid),Trithorax group protein osa (Protein eyelid),GO:0003677; GO:0016055; GO:0035060; GO:0016568; GO:0007480; GO:0008587; GO:0008586; GO:0046530; GO:0045893; GO:0042058; GO:0007379; GO:0006351; GO:0048190,"DNA binding; Wnt receptor signaling pathway; brahma complex; chromatin modification; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; photoreceptor cell differentiation; positive regulation of transcription, DNA-dependent; regulation of epidermal growth factor receptor signaling pathway; segment specification; transcription, DNA-dependent; wing disc dorsal/ventral pattern formation",PF01388;PF12031;,,,,,,,,,OSA_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]" comp136981_c1_seq10,4081,44.0088,0.46618827,0,0,,5.00E-72,Q8NFD5,AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R),AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R),GO:0003677; GO:0016514; GO:0048096; GO:0007399; GO:0003713; GO:0006351,"DNA binding; SWI/SNF complex; chromatin-mediated maintenance of transcription; nervous system development; transcription coactivator activity; transcription, DNA-dependent",PF01388;PF12031;,4.00E-73,CHOYP_LOC100883763.1.1,,,,,,,ARI1B_HUMAN,Homo sapiens (Human),"chromatin-mediated maintenance of transcription [GO:0048096]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]" comp136981_c1_seq11,4066,43.9252,0.46980447,0,0,,5.00E-79,Q8IN94,Trithorax group protein osa (Protein eyelid),Trithorax group protein osa (Protein eyelid),GO:0003677; GO:0016055; GO:0035060; GO:0016568; GO:0007480; GO:0008587; GO:0008586; GO:0046530; GO:0045893; GO:0042058; GO:0007379; GO:0006351; GO:0048190,"DNA binding; Wnt receptor signaling pathway; brahma complex; chromatin modification; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; photoreceptor cell differentiation; positive regulation of transcription, DNA-dependent; regulation of epidermal growth factor receptor signaling pathway; segment specification; transcription, DNA-dependent; wing disc dorsal/ventral pattern formation",PF01388;PF12031;,3.00E-74,CHOYP_OSA.1.2,,,,,,,OSA_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]" comp136981_c1_seq3,4129,43.9574,0.4719633,0,0,,,,,,,,,4.00E-73,CHOYP_LOC100883763.1.1,,,,,,,,, comp136981_c1_seq4,3138,42.0969,0.56347599,0,0,,8.00E-80,Q8IN94,Trithorax group protein osa (Protein eyelid),Trithorax group protein osa (Protein eyelid),GO:0003677; GO:0016055; GO:0035060; GO:0016568; GO:0007480; GO:0008587; GO:0008586; GO:0046530; GO:0045893; GO:0042058; GO:0007379; GO:0006351; GO:0048190,"DNA binding; Wnt receptor signaling pathway; brahma complex; chromatin modification; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; photoreceptor cell differentiation; positive regulation of transcription, DNA-dependent; regulation of epidermal growth factor receptor signaling pathway; segment specification; transcription, DNA-dependent; wing disc dorsal/ventral pattern formation",PF01388;PF12031;,2.00E-74,CHOYP_OSA.1.2,,,,,,,OSA_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]" comp136981_c1_seq7,3201,42.1743,0.56413476,0,0,,1.00E-79,Q8IN94,Trithorax group protein osa (Protein eyelid),Trithorax group protein osa (Protein eyelid),GO:0003677; GO:0016055; GO:0035060; GO:0016568; GO:0007480; GO:0008587; GO:0008586; GO:0046530; GO:0045893; GO:0042058; GO:0007379; GO:0006351; GO:0048190,"DNA binding; Wnt receptor signaling pathway; brahma complex; chromatin modification; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; photoreceptor cell differentiation; positive regulation of transcription, DNA-dependent; regulation of epidermal growth factor receptor signaling pathway; segment specification; transcription, DNA-dependent; wing disc dorsal/ventral pattern formation",PF01388;PF12031;,2.00E-74,CHOYP_OSA.1.2,,,,,,,OSA_DROME,Drosophila melanogaster (Fruit fly),"adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]" comp136981_c1_seq9,4144,43.9913,0.46945526,0,0,,,,,,,,,3.00E-74,CHOYP_OSA.1.2,,,,,,,,, comp136983_c0_seq2,2095,38.6635,0.35224487,8,55,,2.00E-27,Q8Q0U0,Putative ankyrin repeat protein MM_0045,Putative ankyrin repeat protein MM_0045,,,PF12796;,8.00E-66,CHOYP_TVAG_470020.1.8,,,,,,,Y045_METMA,Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia), comp136983_c0_seq3,1869,37.5602,0.37093372,16,144,,6.00E-18,Q2QLC6,"Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)","Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)",GO:0043046; GO:0030154; GO:0031047; GO:0007140; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; cell differentiation; gene silencing by RNA; male meiosis; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF12796;PF07647;,,,,,,,,,ASZ1_CARPS,Carollia perspicillata (Seba's short-tailed bat),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp136985_c1_seq2,587,35.0937,0.39244965,29,50,,,,,,,,,,,8.00E-13,ruditapes_c11503,,,,,,, comp136985_c1_seq4,844,34.4787,0.3209881,161,513,,,,,,,,,,,5.00E-11,ruditapes2_lrc4297,,,,,,, comp136986_c0_seq3,559,49.9106,0.51910765,46,56,,5.00E-06,O14578,Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0048699; GO:0035556; GO:0046872; GO:0007091; GO:0007067; GO:0000070; GO:0050774; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; generation of neurons; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitosis; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,4.00E-43,CHOYP_CIT.1.2,,,,,,,CTRO_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467] comp136987_c0_seq1,1934,39.2968,0.45430303,1335,6008,,0,Q66KC4,Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-),Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-),GO:0016491; GO:0005777; GO:0032934,oxidoreductase activity; peroxisome; sterol binding,PF00106;PF02036;,6.00E-130,CHOYP_NEMVEDRAFT_V1G173950.1.1,4.00E-67,ruditapes_c16375,,,,,HSDL2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp136997_c1_seq1,674,44.6588,0.89689275,3,0,,1.00E-57,Q3SWX0,Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog),Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog),GO:0005769; GO:0016021; GO:0015095; GO:0005886,early endosome; integral to membrane; magnesium ion transmembrane transporter activity; plasma membrane,PF05653;,,,,,,,,,NIPA2_BOVIN,Bos taurus (Bovine),magnesium ion transport [GO:0015693] comp136997_c1_seq2,1460,40.6849,1.08149557,67,23,,9.00E-112,Q5R7Q3,Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog),Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog),GO:0005769; GO:0016021; GO:0015095; GO:0005886,early endosome; integral to membrane; magnesium ion transmembrane transporter activity; plasma membrane,PF05653;,4.00E-29,CHOYP_NIPA2.1.1,,,,,,,NIPA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),magnesium ion transport [GO:0015693] comp137002_c0_seq1,1399,40.243,0.40971112,97,661,,6.00E-126,Q9BRX9,WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1),WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1),GO:0071013; GO:0005737; GO:0000398,"catalytic step 2 spliceosome; cytoplasm; mRNA splicing, via spliceosome",PF00400;,3.00E-81,CHOYP_LOC100372814.1.1,,,,,,,WDR83_HUMAN,Homo sapiens (Human),"MAPK cascade [GO:0000165]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]" comp137003_c0_seq2,1064,31.9549,0.96669545,6,56,,2.00E-17,Q13490,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (IAP-2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2),GO:0035631; GO:0038061; GO:0035666; GO:0007166; GO:0006921; GO:0005829; GO:0045087; GO:0009898; GO:0070266; GO:0043066; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0000209; GO:0039535; GO:0051726; GO:0045595; GO:0042127; GO:2000116; GO:0050727; GO:0060544; GO:0070424; GO:0034121; GO:0006355; GO:0034138; GO:0034142; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; NIK/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; cell surface receptor signaling pathway; cellular component disassembly involved in execution phase of apoptosis; cytosol; innate immune response; internal side of plasma membrane; necroptosis; negative regulation of apoptotic process; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of RIG-I signaling pathway; regulation of cell cycle; regulation of cell differentiation; regulation of cell proliferation; regulation of cysteine-type endopeptidase activity; regulation of inflammatory response; regulation of necroptosis; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of toll-like receptor signaling pathway; regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,3.00E-16,CHOYP_PIAP.2.3,4.00E-13,ruditapes_c19443,,,,,BIRC2_HUMAN,Homo sapiens (Human),"cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp137004_c5_seq1,906,37.0861,0.54788114,159,1631,,2.00E-50,Q9NVV5,Androgen-induced gene 1 protein (AIG-1),Androgen-induced gene 1 protein (AIG-1),GO:0016021,integral to membrane,PF04750;,7.00E-37,CHOYP_AIG1.2.2,,,,,,,AIG1_HUMAN,Homo sapiens (Human), comp137006_c1_seq2,1408,35.5114,0.83950123,0,425,,2.00E-08,Q9JHE4,Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase),Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase),GO:0000139; GO:0006682; GO:0001733; GO:0016021; GO:0042552; GO:0007283,Golgi membrane; galactosylceramide biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane; myelination; spermatogenesis,PF06990;,,,,,,,,,G3ST1_MOUSE,Mus musculus (Mouse),galactosylceramide biosynthetic process [GO:0006682]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283] comp137010_c0_seq1,1938,42.0021,0.5552558,0,0,,4.00E-63,O43663,Protein regulator of cytokinesis 1,Protein regulator of cytokinesis 1,GO:0000910; GO:0005737; GO:0000022; GO:0005634; GO:0005886; GO:0005876; GO:0000922,cytokinesis; cytoplasm; mitotic spindle elongation; nucleus; plasma membrane; spindle microtubule; spindle pole,,,,,,,,,,PRC1_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; mitotic spindle elongation [GO:0000022]; positive regulation of cell proliferation [GO:0008284] comp137010_c0_seq4,1878,42.3323,0.59078967,0,0,,1.00E-53,Q99K43,Protein regulator of cytokinesis 1,Protein regulator of cytokinesis 1,GO:0000910; GO:0005737; GO:0005874; GO:0000226; GO:0005634; GO:0005819; GO:0000922,cytokinesis; cytoplasm; microtubule; microtubule cytoskeleton organization; nucleus; spindle; spindle pole,,,,,,,,,,PRC1_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; positive regulation of cell proliferation [GO:0008284] comp137010_c0_seq7,1926,42.108,0.55663535,0,0,,2.00E-62,O43663,Protein regulator of cytokinesis 1,Protein regulator of cytokinesis 1,GO:0000910; GO:0005737; GO:0000022; GO:0005634; GO:0005886; GO:0005876; GO:0000922,cytokinesis; cytoplasm; mitotic spindle elongation; nucleus; plasma membrane; spindle microtubule; spindle pole,,,,,,,,,,PRC1_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; mitotic spindle elongation [GO:0000022]; positive regulation of cell proliferation [GO:0008284] comp137010_c0_seq8,1845,42.2764,0.56516113,0,0,,6.00E-54,Q99K43,Protein regulator of cytokinesis 1,Protein regulator of cytokinesis 1,GO:0000910; GO:0005737; GO:0005874; GO:0000226; GO:0005634; GO:0005819; GO:0000922,cytokinesis; cytoplasm; microtubule; microtubule cytoskeleton organization; nucleus; spindle; spindle pole,,,,,,,,,,PRC1_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; positive regulation of cell proliferation [GO:0008284] comp137011_c2_seq1,620,42.9032,0.56326677,6,10,,,,,,,,,,,2.00E-20,ruditapes_c28601,,,,,,, comp137011_c2_seq2,439,45.1025,0.45119184,0,0,,6.00E-12,Q4R6P7,Sestrin-1,Sestrin-1 (EC 1.11.1.15),GO:0007050; GO:0005634,cell cycle arrest; nucleus,PF04636;,,,,,,,,,SESN1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cellular oxidant detoxification [GO:0098869]; cellular response to amino acid stimulus [GO:0071230]; negative regulation of TORC1 signaling [GO:1904262]; reactive oxygen species metabolic process [GO:0072593]; regulation of response to reactive oxygen species [GO:1901031] comp137011_c2_seq4,2215,40.8578,0.76465036,2,6,,5.00E-144,Q9CYP7,Sestrin-3,Sestrin-3,GO:0007050; GO:0005634,cell cycle arrest; nucleus,PF04636;,,,,,,,,,SESN3_MOUSE,Mus musculus (Mouse),cellular response to amino acid stimulus [GO:0071230]; glucose homeostasis [GO:0042593]; negative regulation of TORC1 signaling [GO:1904262]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of protein kinase B signaling [GO:0051896]; regulation of response to reactive oxygen species [GO:1901031]; response to insulin [GO:0032868]; TORC2 signaling [GO:0038203] comp137011_c2_seq5,2166,40.8587,0.78000161,0,0,,9.00E-146,P58005,Sestrin-3,Sestrin-3,GO:0007050; GO:0005634,cell cycle arrest; nucleus,PF04636;,8.00E-66,CHOYP_BRAFLDRAFT_219671.2.2,1.00E-30,ruditapes_c18353,,,,,SESN3_HUMAN,Homo sapiens (Human),cellular response to amino acid stimulus [GO:0071230]; negative regulation of TORC1 signaling [GO:1904262]; regulation of response to reactive oxygen species [GO:1901031] comp137014_c2_seq1,1690,40.355,0.59724361,52,230,,2.00E-130,Q6GN15,Cyclin-L1,Cyclin-L1,GO:0006396; GO:0005634; GO:0000079; GO:0006355; GO:0006351,"RNA processing; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00134;,7.00E-129,CHOYP_CCNL1.1.2,,,,,,,CCNL1_XENLA,Xenopus laevis (African clawed frog),"regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]" comp137014_c2_seq4,711,38.3966,0.61161938,13,12,,6.00E-62,Q5RD50,Cyclin-L1,Cyclin-L1,GO:0006396; GO:0016607; GO:0000079; GO:0006355; GO:0006351,"RNA processing; nuclear speck; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00134;,,,,,,,,,CCNL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]" comp137017_c0_seq2,897,41.0256,0.43173131,0,0,,6.00E-20,Q0V9E9,N-lysine methyltransferase SETD8 (EC 2.1.1.-) (Histone-lysine N-methyltransferase SETD8) (EC 2.1.1.43) (SET domain-containing protein 8),N-lysine methyltransferase KMT5A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A) (EC 2.1.1.43) (Lysine-specific methylase 5A) (SET domain-containing protein 8),GO:0051301; GO:0005694; GO:0018024; GO:0007067; GO:0005634; GO:0006355; GO:0006351,"cell division; chromosome; histone-lysine N-methyltransferase activity; mitosis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SETD8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137017_c0_seq6,913,40.7448,0.40358001,0,0,,4.00E-13,Q22795,Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),GO:0009792; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"embryo development ending in birth or egg hatching; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET1_CAEEL,Caenorhabditis elegans,"embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137017_c0_seq7,886,40.6321,0.44595331,0,0,,,,,,,,,6.00E-12,CHOYP_LOC101237965.2.4,,,,,,,,, comp137018_c0_seq2,982,40.6314,0.59440727,32,167,,3.00E-72,A2A825,REM2- and Rab-like small GTPase 1,REM2- and Rab-like small GTPase 1,GO:0005525; GO:0034613; GO:0005929; GO:0042384; GO:0005737; GO:0006887; GO:0005932; GO:0015031; GO:0017157; GO:0031338; GO:0007264,GTP binding; cellular protein localization; cilium; cilium assembly; cytoplasm; exocytosis; microtubule basal body; protein transport; regulation of exocytosis; regulation of vesicle fusion; small GTPase mediated signal transduction,PF00071;,3.00E-23,CHOYP_RSG1.1.1,,,,,,,RSG1_MOUSE,Mus musculus (Mouse),cellular protein localization [GO:0034613]; cilium assembly [GO:0042384]; exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of vesicle fusion [GO:0031338]; small GTPase mediated signal transduction [GO:0007264] comp137020_c0_seq1,2318,37.1872,0.82589051,300,61,,3.00E-62,Q10743,Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) (Fragment),Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) (Fragment),GO:0005798; GO:0007219; GO:0009986; GO:0001701; GO:0016021; GO:0016020; GO:0006509; GO:0046872; GO:0004222; GO:0007162; GO:0005634; GO:0042803; GO:0019901; GO:0006468; GO:0045670; GO:0005802,Golgi-associated vesicle; Notch signaling pathway; cell surface; in utero embryonic development; integral to membrane; membrane; membrane protein ectodomain proteolysis; metal ion binding; metalloendopeptidase activity; negative regulation of cell adhesion; nucleus; protein homodimerization activity; protein kinase binding; protein phosphorylation; regulation of osteoclast differentiation; trans-Golgi network,PF00200;,,,,,,,,,ADA10_RAT,Rattus norvegicus (Rat),in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cell adhesion [GO:0007162]; Notch signaling pathway [GO:0007219]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670] comp137021_c0_seq1,1943,43.2321,0.37049753,0,6,,7.00E-152,A4J0S6,Formate--tetrahydrofolate ligase (EC 6.3.4.3) (Formyltetrahydrofolate synthetase) (FHS) (FTHFS),Formate--tetrahydrofolate ligase (EC 6.3.4.3) (Formyltetrahydrofolate synthetase) (FHS) (FTHFS),GO:0005524; GO:0009396; GO:0004329; GO:0035999,ATP binding; folic acid-containing compound biosynthetic process; formate-tetrahydrofolate ligase activity; tetrahydrofolate interconversion,PF01268;,,,,,,,,,FTHS_DESRM,Desulfotomaculum reducens (strain MI-1),folic acid-containing compound biosynthetic process [GO:0009396]; tetrahydrofolate interconversion [GO:0035999] comp137021_c0_seq2,1572,45.5471,0.40733724,0,0,,2.00E-76,Q11M18,Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)],Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)],GO:0009396; GO:0000105; GO:0004477; GO:0009086; GO:0004488; GO:0006164; GO:0035999,folic acid-containing compound biosynthetic process; histidine biosynthetic process; methenyltetrahydrofolate cyclohydrolase activity; methionine biosynthetic process; methylenetetrahydrofolate dehydrogenase (NADP+) activity; purine nucleotide biosynthetic process; tetrahydrofolate interconversion,PF00763;PF02882;,,,,,,,,,FOLD_MESSB,Chelativorans sp. (strain BNC1),folic acid-containing compound biosynthetic process [GO:0009396]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999] comp137021_c0_seq4,3416,44.4672,0.3900973,30,15,,0,P27653,"C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]","C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]",GO:0005524; GO:0005829; GO:0009396; GO:0004329; GO:0000105; GO:0004477; GO:0009086; GO:0004488; GO:0004486; GO:0009117; GO:0006730; GO:0006164; GO:0035999; GO:0046653,ATP binding; cytosol; folic acid-containing compound biosynthetic process; formate-tetrahydrofolate ligase activity; histidine biosynthetic process; methenyltetrahydrofolate cyclohydrolase activity; methionine biosynthetic process; methylenetetrahydrofolate dehydrogenase (NADP+) activity; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity; nucleotide metabolic process; one-carbon metabolic process; purine nucleotide biosynthetic process; tetrahydrofolate interconversion; tetrahydrofolate metabolic process,PF01268;PF00763;PF02882;,0,CHOYP_C1TC.1.1,,,,,,,C1TC_RAT,Rattus norvegicus (Rat),folic acid-containing compound biosynthetic process [GO:0009396]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; nucleotide metabolic process [GO:0009117]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] comp137021_c0_seq6,1291,40.8211,0.53011374,0,5,,2.00E-87,P27653,"C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]","C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]",GO:0005524; GO:0005829; GO:0009396; GO:0004329; GO:0000105; GO:0004477; GO:0009086; GO:0004488; GO:0004486; GO:0009117; GO:0006730; GO:0006164; GO:0035999; GO:0046653,ATP binding; cytosol; folic acid-containing compound biosynthetic process; formate-tetrahydrofolate ligase activity; histidine biosynthetic process; methenyltetrahydrofolate cyclohydrolase activity; methionine biosynthetic process; methylenetetrahydrofolate dehydrogenase (NADP+) activity; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity; nucleotide metabolic process; one-carbon metabolic process; purine nucleotide biosynthetic process; tetrahydrofolate interconversion; tetrahydrofolate metabolic process,PF01268;PF00763;PF02882;,,,,,,,,,C1TC_RAT,Rattus norvegicus (Rat),folic acid-containing compound biosynthetic process [GO:0009396]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; nucleotide metabolic process [GO:0009117]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] comp137022_c1_seq3,1674,38.6499,0.36819533,7,109,,9.00E-30,D2HBV9,Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3),Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3),GO:0003865; GO:0047751; GO:0019348; GO:0006488; GO:0005783; GO:0005789; GO:0016021; GO:0016628; GO:0016095; GO:0006486,"3-oxo-5-alpha-steroid 4-dehydrogenase activity; cholestenone 5-alpha-reductase activity; dolichol metabolic process; dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; polyprenol catabolic process; protein glycosylation",PF02544;,,,,,,,,,PORED_AILME,Ailuropoda melanoleuca (Giant panda),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichol metabolic process [GO:0019348]; polyprenol catabolic process [GO:0016095]; protein glycosylation [GO:0006486] comp137023_c0_seq1,2345,40.9808,0.71886504,128,164,,0,Q5CD18,TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I),TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I),GO:0005524; GO:0006915; GO:0030154; GO:0016021; GO:0046872; GO:0005886; GO:0040008; GO:0005923; GO:0005024; GO:0007178,ATP binding; apoptotic process; cell differentiation; integral to membrane; metal ion binding; plasma membrane; regulation of growth; tight junction; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase signaling pathway,PF01064;PF00069;PF08515;,4.00E-108,CHOYP_BABO.1.1,,,,,,,TGFR1_PIG,Sus scrofa (Pig),"activin receptor signaling pathway [GO:0032924]; apoptotic process [GO:0006915]; cardiac epithelial to mesenchymal transition [GO:0060317]; endothelial cell activation [GO:0042118]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; mesenchymal cell differentiation [GO:0048762]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp137024_c0_seq1,998,44.1884,0.41417952,42,270,,1.00E-90,Q05AL1,Armadillo repeat-containing protein 8,Armadillo repeat-containing protein 8,,,,,,,,,,,,ARMC8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp137026_c0_seq1,1849,37.4256,0.96535848,87,13,,2.00E-75,Q9Y345,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015375; GO:0016021; GO:0005328; GO:0005886; GO:0007268,glycine:sodium symporter activity; integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane; synaptic transmission,PF00209;,5.00E-30,CHOYP_SC6A9.1.6,,,,,,,SC6A5_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp137033_c0_seq1,949,41.7281,0.36986129,50,248,,2.00E-38,Q92966,snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Proximal sequence element-binding transcription factor subunit beta) (PSE-binding factor subunit beta) (PTF subunit beta) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit),snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Proximal sequence element-binding transcription factor subunit beta) (PSE-binding factor subunit beta) (PTF subunit beta) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit),GO:0003677; GO:0005654; GO:0006355; GO:0009301; GO:0006366; GO:0006383,"DNA binding; nucleoplasm; regulation of transcription, DNA-dependent; snRNA transcription; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter",PF12251;,2.00E-24,CHOYP_SNPC3.1.1,,,,,,,SNPC3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription [GO:0009301]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]" comp137034_c0_seq1,1261,45.9952,0.48019626,0,0,,4.00E-50,Q6UB99,Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1),Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1),GO:0060348; GO:0060325; GO:0001701; GO:0035264; GO:0005634; GO:0042475; GO:0048705; GO:0001894,bone development; face morphogenesis; in utero embryonic development; multicellular organism growth; nucleus; odontogenesis of dentin-containing tooth; skeletal system morphogenesis; tissue homeostasis,PF12796;,6.00E-65,CHOYP_ANR11.1.1,,,,,,,ANR11_HUMAN,Homo sapiens (Human),bone development [GO:0060348]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; odontogenesis of dentin-containing tooth [GO:0042475]; skeletal system morphogenesis [GO:0048705]; tissue homeostasis [GO:0001894] comp137034_c0_seq2,3443,43.5957,0.58703717,183,293,,2.00E-25,Q99728,BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-),BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-),GO:0070531; GO:0031436; GO:0006281; GO:0003723; GO:0007050; GO:0005737; GO:0019900; GO:0043066; GO:0031441; GO:0046826; GO:0043065; GO:0045732; GO:0085020; GO:0042325; GO:0006974; GO:0001894; GO:0004842; GO:0008270,BRCA1-A complex; BRCA1-BARD1 complex; DNA repair; RNA binding; cell cycle arrest; cytoplasm; kinase binding; negative regulation of apoptotic process; negative regulation of mRNA 3'-end processing; negative regulation of protein export from nucleus; positive regulation of apoptotic process; positive regulation of protein catabolic process; protein K6-linked ubiquitination; regulation of phosphorylation; response to DNA damage stimulus; tissue homeostasis; ubiquitin-protein ligase activity; zinc ion binding,PF12796;,2.00E-64,CHOYP_ANR12.1.1,,,,,,,BARD1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA 3'-end processing [GO:0031441]; negative regulation of protein export from nucleus [GO:0046826]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of phosphorylation [GO:0042325]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; tissue homeostasis [GO:0001894] comp137034_c0_seq4,956,46.1297,0.5511545,0,0,,4.00E-28,Q6UB99,Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1),Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1),GO:0060348; GO:0060325; GO:0001701; GO:0035264; GO:0005634; GO:0042475; GO:0048705; GO:0001894,bone development; face morphogenesis; in utero embryonic development; multicellular organism growth; nucleus; odontogenesis of dentin-containing tooth; skeletal system morphogenesis; tissue homeostasis,PF12796;,,,,,,,,,ANR11_HUMAN,Homo sapiens (Human),bone development [GO:0060348]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; odontogenesis of dentin-containing tooth [GO:0042475]; skeletal system morphogenesis [GO:0048705]; tissue homeostasis [GO:0001894] comp137037_c0_seq2,427,41.452,0.57744515,7147,25452,,,,,,,,,4.00E-23,CHOYP_PROF2.1.1,2.00E-38,ruditapes_c1994,,,,,,, comp137038_c0_seq1,1949,41.4058,0.37768041,259,1546,,4.00E-141,P41214,Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin),Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin),GO:0005737; GO:0006886; GO:0004872; GO:0003743,cytoplasm; intracellular protein transport; receptor activity; translation initiation factor activity,PF01253;,2.00E-21,CHOYP_LOC101067905.1.1,6.00E-65,ruditapes_c26391,,,,,EIF2D_HUMAN,Homo sapiens (Human),formation of translation preinitiation complex [GO:0001731]; intracellular protein transport [GO:0006886]; IRES-dependent translational initiation [GO:0002192]; ribosome disassembly [GO:0032790] comp137039_c4_seq1,728,38.0495,0.68608307,21,75,,5.00E-19,Q3ZCX4,Zinc finger protein 568,Zinc finger protein 568,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN568_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137040_c0_seq1,1661,33.8952,0.33673559,18,19,,3.00E-24,Q8IVU9,Uncharacterized protein C10orf107,Uncharacterized protein C10orf107,,,PF14769;,1.00E-30,CHOYP_LOC100378886.1.2,4.00E-72,ruditapes_c12963,,,,,CJ107_HUMAN,Homo sapiens (Human), comp137040_c0_seq2,1036,29.4402,0.40448161,3,21,,,,,,,,,,,4.00E-44,ruditapes2_c1082,,,,,,, comp137040_c0_seq4,1669,33.2534,0.39128411,58,0,,,,,,,,,3.00E-38,CHOYP_LOC592209.1.1,,,,,,,,, comp137041_c0_seq2,1864,44.5279,0.39873869,2,83,,0,Q96NN9,Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein),Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein),GO:0051537; GO:0045454; GO:0005783; GO:0097194; GO:0050660; GO:0046872; GO:0005743; GO:0016491,"2 iron, 2 sulfur cluster binding; cell redox homeostasis; endoplasmic reticulum; execution phase of apoptosis; flavin adenine dinucleotide binding; metal ion binding; mitochondrial inner membrane; oxidoreductase activity",PF07992;PF14759;PF00355;,3.00E-159,CHOYP_LOC100150876.1.1,,,,,,,AIFM3_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; execution phase of apoptosis [GO:0097194] comp137041_c0_seq3,2005,43.2918,0.39165461,9,0,,0,Q96NN9,Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein),Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein),GO:0051537; GO:0045454; GO:0005783; GO:0097194; GO:0050660; GO:0046872; GO:0005743; GO:0016491,"2 iron, 2 sulfur cluster binding; cell redox homeostasis; endoplasmic reticulum; execution phase of apoptosis; flavin adenine dinucleotide binding; metal ion binding; mitochondrial inner membrane; oxidoreductase activity",PF07992;PF14759;PF00355;,,,,,,,,,AIFM3_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; execution phase of apoptosis [GO:0097194] comp137041_c0_seq4,2074,44.4552,0.39798237,7,58,,,,,,,,,1.00E-157,CHOYP_LOC100150876.1.1,,,,,,,,, comp137045_c2_seq1,969,36.7389,0.61299357,0,3,,,,,,,,,,,3.00E-20,ruditapes2_c1223,,,,,,, comp137046_c0_seq1,1685,35.549,0.50837595,2,0,,,,,,,,,1.00E-11,CHOYP_LOC100115002.1.1,,,,,,,,, comp137047_c0_seq2,1412,43.3428,0.38021912,74,740,,7.00E-18,P34447,"Uncharacterized protein F54F2.2, isoform a","Uncharacterized protein F54F2.2, isoform a",GO:0003677; GO:0016246; GO:0000785; GO:0003682; GO:0005634; GO:0008270,DNA binding; RNA interference; chromatin; chromatin binding; nucleus; zinc ion binding,,1.00E-23,CHOYP_PHUM_PHUM498110.1.1,,,,,,,YM2A_CAEEL,Caenorhabditis elegans,RNA interference [GO:0016246] comp137048_c0_seq1,1095,47.6712,0.65968903,0,0,,4.00E-21,Q15746,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0060414; GO:0032060; GO:0071476; GO:0032154; GO:0005829; GO:0030027; GO:0046872; GO:0004687; GO:0005886; GO:0051928; GO:0030335; GO:0090303; GO:0001725; GO:0014820,ATP binding; aorta smooth muscle tissue morphogenesis; bleb assembly; cellular hypotonic response; cleavage furrow; cytosol; lamellipodium; metal ion binding; myosin light chain kinase activity; plasma membrane; positive regulation of calcium ion transport; positive regulation of cell migration; positive regulation of wound healing; stress fiber; tonic smooth muscle contraction,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_HUMAN,Homo sapiens (Human),aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792] comp137048_c0_seq2,1109,48.2417,0.46623022,8,0,,1.00E-21,Q9U308,Juxtamembrane domain-associated catenin (p120 catenin homolog),Juxtamembrane domain-associated catenin (p120 catenin homolog),GO:0007155; GO:0005913; GO:0010172; GO:0032956; GO:0032880,cell adhesion; cell-cell adherens junction; embryonic body morphogenesis; regulation of actin cytoskeleton organization; regulation of protein localization,PF00514;PF00041;,,,,,,,,,JAC1_CAEEL,Caenorhabditis elegans,embryonic body morphogenesis [GO:0010172]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; single organismal cell-cell adhesion [GO:0016337] comp137048_c0_seq3,2174,48.0681,0.5738451,30,2,,5.00E-93,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,8.00E-104,CHOYP_TITIN.19.19,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp137048_c3_seq1,1231,50.2031,0.58102892,95,42,,1.00E-56,Q3KNY0,Immunoglobulin-like and fibronectin type III domain-containing protein 1,Immunoglobulin-like and fibronectin type III domain-containing protein 1,GO:0030018; GO:0005634,Z disc; nucleus,PF00041;PF07679;,,,,,,,,,IGFN1_MOUSE,Mus musculus (Mouse), comp137048_c4_seq1,1856,47.1444,0.63091971,0,8,,2.00E-87,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,8.00E-27,CHOYP_TTN.8.9,4.00E-22,ruditapes_c21461,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp137048_c4_seq2,1834,46.4558,0.64722727,5,0,,5.00E-27,Q8NDA2,Hemicentin-2,Hemicentin-2,GO:0005509; GO:0005578; GO:0050896,calcium ion binding; proteinaceous extracellular matrix; response to stimulus,PF12662;PF07645;PF07474;PF07679;,8.00E-27,CHOYP_TITIN.19.19,2.00E-12,ruditapes_c31218,,,,,HMCN2_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896] comp137048_c6_seq1,1019,48.8714,0.55935538,31,9,,2.00E-39,Q02173,"M-protein, striated muscle","M-protein, striated muscle",,,PF00041;PF07679;,2.00E-13,CHOYP_PEVK.3.3,,,,,,,MPSF_CHICK,Gallus gallus (Chicken), comp137050_c1_seq1,439,46.697,0.4615702,3,40,,4.00E-11,Q86SQ6,Probable G-protein coupled receptor 123,Adhesion G protein-coupled receptor A1 (G-protein coupled receptor 123),GO:0004930; GO:0005737; GO:0016021; GO:0005886,G-protein coupled receptor activity; cytoplasm; integral to membrane; plasma membrane,PF00002;,4.00E-23,CHOYP_GP125.1.1,,,,,,,GP123_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; signal transduction [GO:0007165] comp137051_c0_seq3,1361,39.4563,0.48024059,0,0,,9.00E-19,Q7DFU6,Putative uncharacterized protein YghX,Putative uncharacterized protein YghX,GO:0016787,hydrolase activity,PF01738;,,,,,,,,,YGHX_ECOLI,Escherichia coli (strain K12), comp137051_c0_seq4,952,44.5378,0.41625333,0,0,,1.00E-17,O67802,Putative carboxymethylenebutenolidase (EC 3.1.1.45) (Dienelactone hydrolase) (DLH),Putative carboxymethylenebutenolidase (EC 3.1.1.45) (Dienelactone hydrolase) (DLH),GO:0008806,carboxymethylenebutenolidase activity,PF01738;,4.00E-27,CHOYP_NEMVEDRAFT_V1G164392.2.3,5.00E-68,ruditapes_c11575,,,,,DLHH_AQUAE,Aquifex aeolicus (strain VF5), comp137052_c0_seq1,2498,42.3139,0.5380713,505,3894,,2.00E-153,Q9H8H2,Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain),Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain),GO:0005524; GO:0008026; GO:0003723; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus,PF00270;PF13959;PF00271;,1.00E-31,CHOYP_DDX31.1.1,,,,,,,DDX31_HUMAN,Homo sapiens (Human),ribosome biogenesis [GO:0042254]; RNA secondary structure unwinding [GO:0010501] comp137055_c0_seq1,1395,45.8781,0.36879202,76,235,,1.00E-43,Q68FR2,Bridging integrator 2,Bridging integrator 2,GO:0060326; GO:0005938; GO:0030054; GO:0042995; GO:0097320; GO:0001891; GO:0006911; GO:0005543; GO:0002102; GO:0071800,"cell chemotaxis; cell cortex; cell junction; cell projection; membrane tubulation; phagocytic cup; phagocytosis, engulfment; phospholipid binding; podosome; podosome assembly",PF03114;,5.00E-28,CHOYP_LOC100879890.1.1,,,,,,,BIN2_RAT,Rattus norvegicus (Rat),cell chemotaxis [GO:0060326]; membrane tubulation [GO:0097320]; podosome assembly [GO:0071800] comp137057_c0_seq1,1346,39.4502,0.67244367,112,1002,,4.00E-51,Q68EY7,Coiled-coil domain-containing protein 124-A,Coiled-coil domain-containing protein 124-A,GO:0007049; GO:0051301; GO:0005737; GO:0005815; GO:0030496,cell cycle; cell division; cytoplasm; microtubule organizing center; midbody,PF06244;,,,,,,,,,C124A_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301] comp137060_c0_seq1,1002,40.02,0.39922424,478,2431,,4.00E-19,Q9R0C0,Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC-1 subunit 6) (Pallid protein) (Pallidin) (Syntaxin 13-interacting protein),Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC-1 subunit 6) (Pallid protein) (Pallidin) (Syntaxin 13-interacting protein),GO:0031083; GO:0031201; GO:0051015; GO:0008089; GO:0048490; GO:0007596; GO:0012505; GO:0005768; GO:0035646; GO:0019898; GO:0030318; GO:0032402; GO:0031175; GO:0032816; GO:0050942; GO:0042803; GO:0033299; GO:0030133; GO:0006904; GO:0006906,BLOC-1 complex; SNARE complex; actin filament binding; anterograde axon cargo transport; anterograde synaptic vesicle transport; blood coagulation; endomembrane system; endosome; endosome to melanosome transport; extrinsic to membrane; melanocyte differentiation; melanosome transport; neuron projection development; positive regulation of natural killer cell activation; positive regulation of pigment cell differentiation; protein homodimerization activity; secretion of lysosomal enzymes; transport vesicle; vesicle docking involved in exocytosis; vesicle fusion,PF14712;,,,,,,,,,PLDN_MOUSE,Mus musculus (Mouse),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; blood coagulation [GO:0007596]; endosome to melanosome transport [GO:0035646]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; membrane fusion [GO:0061025]; neuron projection development [GO:0031175]; pigmentation [GO:0043473]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of pigment cell differentiation [GO:0050942]; secretion of lysosomal enzymes [GO:0033299]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906] comp137061_c0_seq1,1412,38.881,0.5635622,9,7,,6.00E-19,B1WB06,Methyltransferase-like protein 24 (EC 2.1.1.-),Methyltransferase-like protein 24 (EC 2.1.1.-),GO:0005576; GO:0008168,extracellular region; methyltransferase activity,PF13383;,,,,,,,,,MET24_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp137061_c0_seq3,1425,38.8772,0.5587777,14,21,,6.00E-19,B1WB06,Methyltransferase-like protein 24 (EC 2.1.1.-),Methyltransferase-like protein 24 (EC 2.1.1.-),GO:0005576; GO:0008168,extracellular region; methyltransferase activity,PF13383;,,,,,,,,,MET24_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp137063_c0_seq1,1619,40.8277,0.91969635,0,4,,3.00E-14,Q5SVZ6,Zinc finger MYM-type protein 1,Zinc finger MYM-type protein 1,GO:0003676; GO:0005634; GO:0008270,nucleic acid binding; nucleus; zinc ion binding,PF05699;PF14291;PF06467;,,,,,,,,,ZMYM1_HUMAN,Homo sapiens (Human), comp137063_c0_seq3,1583,40.6191,0.93531875,5,45,,1.00E-06,O43422,52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0),52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12),GO:0003677; GO:0046872; GO:0008285; GO:0005634; GO:0006950; GO:0007165,DNA binding; metal ion binding; negative regulation of cell proliferation; nucleus; response to stress; signal transduction,PF05699;PF14291;PF05485;,,,,,,,,,P52K_HUMAN,Homo sapiens (Human),negative regulation of cell proliferation [GO:0008285]; response to stress [GO:0006950]; signal transduction [GO:0007165] comp137066_c0_seq1,1760,39.2614,0.49542215,67,422,,3.00E-107,Q9DCL4,Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1),Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1),GO:0008168,methyltransferase activity,PF01795;,,,,,,,,,MET15_MOUSE,Mus musculus (Mouse),rRNA base methylation [GO:0070475] comp137071_c2_seq1,972,42.4897,1.08111226,7,741,female>male,2.00E-15,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp137071_c5_seq5,307,42.671,0.89405883,0,0,,,,,,,,,,,2.00E-17,ruditapes_c28149,,,,,,, comp137081_c0_seq1,1427,40.925,0.33743326,106,42,,2.00E-21,Q5RDN3,Proteasome inhibitor PI31 subunit,Proteasome inhibitor PI31 subunit,GO:0000502,proteasome complex,PF08577;PF11566;,2.00E-28,CHOYP_LOC577551.1.1,5.00E-20,ruditapes_c22524,,,,,PSMF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of proteasomal protein catabolic process [GO:1901799]; ubiquitin-dependent protein catabolic process [GO:0006511] comp137084_c0_seq1,390,42.5641,0.46375398,0,0,,1.00E-20,Q8VX13,Protein disulfide isomerase-like 1-3 (AtPDIL1-3) (EC 5.3.4.1) (Protein disulfide isomerase 1) (AtPDI1) (Protein disulfide isomerase-like 2-1) (AtPDIL2-1),Protein disulfide isomerase-like 1-3 (AtPDIL1-3) (EC 5.3.4.1) (Protein disulfide isomerase 1) (AtPDI1) (Protein disulfide isomerase-like 2-1) (AtPDIL2-1),GO:0045454; GO:0009507; GO:0005783; GO:0005788; GO:0003756; GO:0034976; GO:0005774,cell redox homeostasis; chloroplast; endoplasmic reticulum; endoplasmic reticulum lumen; protein disulfide isomerase activity; response to endoplasmic reticulum stress; vacuolar membrane,PF00085;,,,,,,,,,PDI13_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp137084_c0_seq2,1148,41.3763,0.51203247,6,48,,8.00E-77,Q2KIL5,Protein disulfide-isomerase A5 (EC 5.3.4.1),Protein disulfide-isomerase A5 (EC 5.3.4.1),GO:0045454; GO:0005788; GO:0006662; GO:0003756; GO:0015035; GO:0006457; GO:0006950,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding; response to stress,PF00085;,,,,,,,,,PDIA5_BOVIN,Bos taurus (Bovine),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp137084_c0_seq3,926,40.9287,0.51932834,8,7,,1.00E-42,P13667,Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72),Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72),GO:0045454; GO:0009986; GO:0005788; GO:0006662; GO:0042470; GO:0003756; GO:0015035; GO:0009306,cell redox homeostasis; cell surface; endoplasmic reticulum lumen; glycerol ether metabolic process; melanosome; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein secretion,PF00085;,,,,,,,,,PDIA4_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976] comp137084_c0_seq4,769,41.4824,0.60161299,7,55,,2.00E-13,P00275,Thioredoxin C-1,Thioredoxin C-1,GO:0045454; GO:0006662; GO:0015035,cell redox homeostasis; glycerol ether metabolic process; protein disulfide oxidoreductase activity,PF00085;,2.00E-61,CHOYP_BRAFLDRAFT_207882.1.1,,,,,,,THIO1_CORNE,Corynebacterium nephridii,cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662] comp137084_c0_seq5,1305,40.6897,0.58480462,1,24,,2.00E-74,Q5I0H9,Protein disulfide-isomerase A5 (EC 5.3.4.1),Protein disulfide-isomerase A5 (EC 5.3.4.1),GO:0045454; GO:0005788; GO:0006662; GO:0003756; GO:0015035; GO:0006457; GO:0006950,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding; response to stress,PF00085;,,,,,,,,,PDIA5_RAT,Rattus norvegicus (Rat),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp137084_c0_seq6,612,42.6471,0.4381191,4,18,,2.00E-20,Q8VX13,Protein disulfide isomerase-like 1-3 (AtPDIL1-3) (EC 5.3.4.1) (Protein disulfide isomerase 1) (AtPDI1) (Protein disulfide isomerase-like 2-1) (AtPDIL2-1),Protein disulfide isomerase-like 1-3 (AtPDIL1-3) (EC 5.3.4.1) (Protein disulfide isomerase 1) (AtPDI1) (Protein disulfide isomerase-like 2-1) (AtPDIL2-1),GO:0045454; GO:0009507; GO:0005783; GO:0005788; GO:0003756; GO:0034976; GO:0005774,cell redox homeostasis; chloroplast; endoplasmic reticulum; endoplasmic reticulum lumen; protein disulfide isomerase activity; response to endoplasmic reticulum stress; vacuolar membrane,PF00085;,5.00E-43,CHOYP_LOC100372340.2.3,,,,,,,PDI13_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp137084_c0_seq7,385,42.5974,0.34464518,23,140,,,,,,,,,2.00E-19,CHOYP_LOC100372340.3.3,,,,,,,,, comp137085_c0_seq1,3428,38.9732,0.59660044,75,45,,3.00E-33,O14646,Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),GO:0005524; GO:0004003; GO:0003677; GO:0006338; GO:0005737; GO:0035064; GO:0005634; GO:0006357; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; DNA binding; chromatin remodeling; cytoplasm; methylated histone residue binding; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00385;PF13907;PF00271;PF00176;,8.00E-37,CHOYP_CHD2.1.1,,,,,,,CHD1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; positive regulation by host of viral transcription [GO:0043923]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp137085_c0_seq3,1322,39.9395,0.66625937,3,0,,2.00E-27,A9X4T1,Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),GO:0005524; GO:0008026; GO:0003677; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent helicase activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00385;PF13907;PF00271;PF00176;,3.00E-37,CHOYP_CHD2.1.1,,,,,,,CHD1_BOMMO,Bombyx mori (Silk moth),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137086_c0_seq1,4127,40.1018,0.561032,4201,17015,,0,P70168,Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG),Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG),GO:0005737; GO:0005635; GO:0043234; GO:0008565; GO:0006610,cytoplasm; nuclear envelope; protein complex; protein transporter activity; ribosomal protein import into nucleus,PF03810;,0,CHOYP_LOC100533387.1.1,,,,,,,IMB1_MOUSE,Mus musculus (Mouse),"astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]" comp137090_c0_seq1,894,36.4653,0.67394663,191,1272,,5.00E-06,Q922M7,Ashwin,Ashwin,GO:0048598; GO:0072669,embryonic morphogenesis; tRNA-splicing ligase complex,PF15323;,,,5.00E-24,ruditapes_c8125,,,,,ASHWN_MOUSE,Mus musculus (Mouse),embryonic morphogenesis [GO:0048598] comp137092_c0_seq1,1774,38.6697,0.63958497,0,0,,9.00E-31,Q5R601,Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A),Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A),GO:0008219; GO:0005783; GO:0005789; GO:0016021; GO:0031175; GO:0070972; GO:0005198,cell death; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; neuron projection development; protein localization to endoplasmic reticulum; structural molecule activity,PF00635;,4.00E-12,CHOYP_VP33.1.2,,,,,,,VAPA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell death [GO:0008219]; neuron projection development [GO:0031175]; protein localization to endoplasmic reticulum [GO:0070972] comp137092_c0_seq2,362,39.2265,0.57791486,0,10,,1.00E-06,Q9LVU1,Vesicle-associated protein 2-1 (Plant VAP homolog 21) (AtPVA21) (VAMP-associated protein 2-1),"Vesicle-associated protein 2-1 (Plant VAP homolog 21) (AtPVA21) (VAMP-associated protein 2-1) [Cleaved into: Vesicle-associated protein 2-1, N-terminally processed]",GO:0005783; GO:0005789; GO:0016021; GO:0005886; GO:0005198,endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; plasma membrane; structural molecule activity,PF00635;,,,,,,,,,VAP21_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp137092_c0_seq3,1737,38.6874,0.63660181,0,0,,4.00E-08,Q6Q595,Vesicle-associated membrane protein-associated protein SCS22 (VAMP-associated protein SCS22) (VAP homolog 2),Vesicle-associated membrane protein-associated protein SCS22 (VAMP-associated protein SCS22) (VAP homolog 2),GO:0090158; GO:0016021; GO:0008654; GO:0060304; GO:0005198,endoplasmic reticulum membrane organization; integral to membrane; phospholipid biosynthetic process; regulation of phosphatidylinositol dephosphorylation; structural molecule activity,PF00635;,,,,,,,,,SCS22_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),endoplasmic reticulum membrane organization [GO:0090158]; phospholipid biosynthetic process [GO:0008654]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] comp137092_c0_seq4,827,42.0798,0.5746208,0,0,,4.00E-08,Q10484,Uncharacterized protein C17C9.12,Uncharacterized protein C17C9.12,GO:0005829; GO:0006020; GO:0030176; GO:0008654; GO:0005198,cytosol; inositol metabolic process; integral to endoplasmic reticulum membrane; phospholipid biosynthetic process; structural molecule activity,PF00635;,2.00E-11,CHOYP_VP33.2.2,,,,,,,YDFC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),maintenance of ER location [GO:0051685]; phospholipid biosynthetic process [GO:0008654] comp137092_c0_seq5,864,41.8981,0.58151338,0,0,,5.00E-09,O60119,Vesicle-associated membrane protein-associated protein C16G5.05c (VAMP-associated protein C16G5.05c) (VAP homolog 1),Vesicle-associated membrane protein-associated protein C16G5.05c (VAMP-associated protein C16G5.05c) (VAP homolog 1),GO:0006020; GO:0030176; GO:0008654; GO:0005198,inositol metabolic process; integral to endoplasmic reticulum membrane; phospholipid biosynthetic process; structural molecule activity,PF00635;,2.00E-12,CHOYP_VP33.1.2,,,,,,,YH75_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),maintenance of ER location [GO:0051685]; phospholipid biosynthetic process [GO:0008654] comp137094_c0_seq1,2299,35.4067,0.56001958,23569,37543,,2.00E-56,Q24537,High mobility group protein DSP1 (Protein dorsal switch 1),High mobility group protein DSP1 (Protein dorsal switch 1),GO:0008301; GO:0006268; GO:0006338; GO:0035218; GO:0017055; GO:0008348; GO:0005634; GO:0005700; GO:0043388; GO:0007379; GO:0003697,"DNA binding, bending; DNA unwinding involved in DNA replication; chromatin remodeling; leg disc development; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly; negative regulation of antimicrobial humoral response; nucleus; polytene chromosome; positive regulation of DNA binding; segment specification; single-stranded DNA binding",PF00505;PF09011;,8.00E-60,CHOYP_ISCW_ISCW017350.1.1,,,,,,,HMG2_DROME,Drosophila melanogaster (Fruit fly),"chromatin remodeling [GO:0006338]; developmental process [GO:0032502]; DNA unwinding involved in DNA replication [GO:0006268]; leg disc development [GO:0035218]; negative regulation of antimicrobial humoral response [GO:0008348]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of DNA binding [GO:0043388]; segment specification [GO:0007379]" comp137097_c0_seq4,2604,47.1198,0.3961481,0,0,,9.00E-177,P11654,Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),GO:0005789; GO:0051028; GO:0031965; GO:0005643; GO:0046983; GO:0015031; GO:0017056,endoplasmic reticulum membrane; mRNA transport; nuclear membrane; nuclear pore; protein dimerization activity; protein transport; structural constituent of nuclear pore,PF02368;,1.00E-25,CHOYP_NUP210.1.1,,,,,,,PO210_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp137097_c0_seq7,1287,45.4545,0.4289557,0,0,,6.00E-89,P11654,Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa),GO:0005789; GO:0051028; GO:0031965; GO:0005643; GO:0046983; GO:0015031; GO:0017056,endoplasmic reticulum membrane; mRNA transport; nuclear membrane; nuclear pore; protein dimerization activity; protein transport; structural constituent of nuclear pore,PF02368;,,,,,,,,,PO210_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp137099_c1_seq1,603,41.791,0.77041028,0,0,,,,,,,,,1.00E-18,CHOYP_BRAFLDRAFT_99018.1.1,,,,,,,,, comp137099_c1_seq4,595,43.0252,0.73399222,0,0,,4.00E-13,P55567,Uncharacterized protein y4mH,Uncharacterized protein y4mH,GO:0003824,catalytic activity,PF04909;,,,,,,,,,Y4MH_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234), comp137108_c0_seq2,1526,38.4666,0.63711493,68,332,,5.00E-58,Q9D6J3,Coiled-coil domain-containing protein 94,Coiled-coil domain-containing protein 94,,,PF04502;,6.00E-91,CHOYP_NEMVEDRAFT_V1G237797.1.1,,,,,,,CCD94_MOUSE,Mus musculus (Mouse), comp137109_c0_seq1,3234,36.9202,0.58075194,4775,2714,,0,P15170,Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (G1 to S phase transition protein 1 homolog),Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (G1 to S phase transition protein 1 homolog),GO:0000082; GO:0005525; GO:0003924; GO:0005622; GO:0000184; GO:0006479; GO:0003747,"G1/S transition of mitotic cell cycle; GTP binding; GTPase activity; intracellular; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; protein methylation; translation release factor activity",PF03144;PF03143;,0,CHOYP_ERF3A.1.1,,,,,,,ERF3A_HUMAN,Homo sapiens (Human),"cytoplasmic translational termination [GO:0002184]; G1/S transition of mitotic cell cycle [GO:0000082]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]" comp137114_c0_seq1,1407,41.72,0.52279341,0,0,,,,,,,,,6.00E-40,CHOYP_CEP89.2.2,,,,,,,,, comp137114_c0_seq3,2326,45.1849,0.48720642,3,9,,5.00E-79,Q9CZX2,Centrosomal protein of 89 kDa (Cep89) (Coiled-coil domain-containing protein 123),Centrosomal protein of 89 kDa (Cep89) (Coiled-coil domain-containing protein 123),GO:0005814; GO:0042384; GO:0005829; GO:0005758; GO:0005886; GO:0000922,centriole; cilium assembly; cytosol; mitochondrial intermembrane space; plasma membrane; spindle pole,,1.00E-39,CHOYP_CEP89.2.2,,,,,,,CEP89_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; nonmotile primary cilium assembly [GO:0035058] comp137115_c1_seq5,472,38.1356,0.64306308,1,43,,4.00E-59,Q05144,Ras-related C3 botulinum toxin substrate 2 (Protein EN-7) (p21-Rac2),Ras-related C3 botulinum toxin substrate 2 (Protein EN-7) (p21-Rac2),GO:0005525; GO:0003924; GO:0030036; GO:0030031; GO:0006935; GO:0005737; GO:0016020; GO:0005635; GO:0008284; GO:0060263; GO:0007264,GTP binding; GTPase activity; actin cytoskeleton organization; cell projection assembly; chemotaxis; cytoplasm; membrane; nuclear envelope; positive regulation of cell proliferation; regulation of respiratory burst; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAC2_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; bone resorption [GO:0045453]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; G-protein coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of cell-substrate adhesion [GO:0010810]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of neutrophil migration [GO:1902622]; regulation of respiratory burst [GO:0060263]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264] comp137115_c1_seq6,272,41.9118,0.8402699,16,0,,2.00E-36,Q6RUV5,Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),GO:0005525; GO:0003924; GO:0000139; GO:0016601; GO:0060071; GO:0007015; GO:0048532; GO:0002093; GO:0007411; GO:0045453; GO:0008283; GO:0045216; GO:0021799; GO:0090103; GO:0031410; GO:0048813; GO:0071542; GO:0021831; GO:0043652; GO:0003382; GO:0019897; GO:0006972; GO:0030027; GO:0030032; GO:0002551; GO:0042470; GO:0001891; GO:0045740; GO:0030838; GO:0043552; GO:0001934; GO:0030334; GO:0097178; GO:0032587; GO:0034446,"GTP binding; GTPase activity; Golgi membrane; Rac protein signal transduction; Wnt receptor signaling pathway, planar cell polarity pathway; actin filament organization; anatomical structure arrangement; auditory receptor cell morphogenesis; axon guidance; bone resorption; cell proliferation; cell-cell junction organization; cerebral cortex radially oriented cell migration; cochlea morphogenesis; cytoplasmic vesicle; dendrite morphogenesis; dopaminergic neuron differentiation; embryonic olfactory bulb interneuron precursor migration; engulfment of apoptotic cell; epithelial cell morphogenesis; extrinsic to plasma membrane; hyperosmotic response; lamellipodium; lamellipodium assembly; mast cell chemotaxis; melanosome; phagocytic cup; positive regulation of DNA replication; positive regulation of actin filament polymerization; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of protein phosphorylation; regulation of cell migration; ruffle assembly; ruffle membrane; substrate adhesion-dependent cell spreading",PF00071;,2.00E-12,CHOYP_RAC1.3.3,,,,,,,RAC1_RAT,Rattus norvegicus (Rat),"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp137125_c0_seq1,2553,44.6142,0.48699634,138,26,,3.00E-54,Q8CB62,Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8),Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8),GO:0005814; GO:0007099; GO:0051299; GO:0000910,centriole; centriole replication; centrosome separation; cytokinesis,,,,,,,,,,CNTRB_MOUSE,Mus musculus (Mouse),centriole replication [GO:0007099]; centrosome separation [GO:0051299]; mitotic cytokinetic process [GO:1902410] comp137125_c0_seq2,1526,45.0852,0.49627152,11,0,,,,,,,,,5.00E-79,CHOYP_CNTROB.1.1,,,,,,,,, comp137128_c0_seq1,1812,38.7417,0.44390954,14,20,,,,,,,,,4.00E-157,CHOYP_CNOT7.2.2,,,4.00E-109,AM861629.p.cg.6,3,female gonad,,, comp137128_c0_seq2,1787,38.6682,0.40681578,7,22,,1.00E-145,Q9UIV1,CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a),CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a),GO:0030014; GO:0003723; GO:0005975; GO:0000932; GO:0033962; GO:0005829; GO:0000290; GO:0043928; GO:0035195; GO:0046872; GO:0008285; GO:0000289; GO:0005634; GO:0004535; GO:0008284; GO:1900153; GO:0060213; GO:0045944; GO:0006417; GO:0003700; GO:0004871; GO:0006351,"CCR4-NOT complex; RNA binding; carbohydrate metabolic process; cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; cytosol; deadenylation-dependent decapping of nuclear-transcribed mRNA; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene silencing by miRNA; metal ion binding; negative regulation of cell proliferation; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; poly(A)-specific ribonuclease activity; positive regulation of cell proliferation; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; positive regulation of transcription from RNA polymerase II promoter; regulation of translation; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription, DNA-dependent",PF04857;,,,,,,,,,CNOT7_HUMAN,Homo sapiens (Human),"carbohydrate metabolic process [GO:0005975]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; gene silencing by RNA [GO:0031047]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp137131_c0_seq1,1354,45.1256,0.40392408,348,618,,0,P15651,"Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase)","Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase)",GO:0003995; GO:0046359; GO:0004085; GO:0033539; GO:0000062; GO:0050660; GO:0005759; GO:0031966; GO:0051289; GO:0051384; GO:0042594,acyl-CoA dehydrogenase activity; butyrate catabolic process; butyryl-CoA dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty-acyl-CoA binding; flavin adenine dinucleotide binding; mitochondrial matrix; mitochondrial membrane; protein homotetramerization; response to glucocorticoid stimulus; response to starvation,PF00441;PF02770;PF02771;,0,CHOYP_NEMVEDRAFT_V1G179716.1.1,,,,,,,ACADS_RAT,Rattus norvegicus (Rat),butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594] comp137135_c0_seq1,1758,33.6177,0.60578598,4911,14111,,3.00E-74,Q71U00,S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1),S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1),GO:0019005; GO:0016567; GO:0006511,SCF ubiquitin ligase complex; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF01466;PF03931;,1.00E-107,CHOYP_LOC100862999.1.1,3.00E-48,ruditapes2_c1926,,,,,SKP1_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp137139_c0_seq1,1716,45.979,0.50099223,173,1406,,0,Q9VW26,"Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase)","Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase)",GO:0055129; GO:0005759; GO:0022008; GO:0006591; GO:0004587; GO:0030170,L-proline biosynthetic process; mitochondrial matrix; neurogenesis; ornithine metabolic process; ornithine-oxo-acid transaminase activity; pyridoxal phosphate binding,PF00202;,2.00E-160,CHOYP_OAT.1.1,,,,,,,OAT_DROME,Drosophila melanogaster (Fruit fly),arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; L-proline biosynthetic process [GO:0055129]; neurogenesis [GO:0022008]; ornithine metabolic process [GO:0006591] comp137141_c0_seq2,1277,42.8348,0.37799491,398,548,,1.00E-104,Q5U4F6,WD repeat-containing protein 34,WD repeat-containing protein 34,GO:0005737,cytoplasm,PF00400;,8.00E-76,CHOYP_LOC100373578.1.1,,,,,,,WDR34_MOUSE,Mus musculus (Mouse), comp137142_c0_seq3,2571,39.6733,0.49228926,234,194,,0,Q7TPD1,F-box only protein 11,F-box only protein 11,GO:0005694; GO:0005634; GO:0007605; GO:0004842; GO:0008270,chromosome; nucleus; sensory perception of sound; ubiquitin-protein ligase activity; zinc ion binding,PF12937;PF05048;PF02207;,0,CHOYP_LOC100882331.1.1,,,,,,,FBX11_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464]; sensory perception of sound [GO:0007605] comp137143_c0_seq1,779,33.7612,0.792116,44,414,,,,,,,,,8.00E-42,CHOYP_DENND4A.1.1,,,,,,,,, comp137143_c0_seq2,789,32.9531,0.77665255,26,211,,2.00E-66,Q2KMM2,Trafficking protein particle complex subunit 1,Trafficking protein particle complex subunit 1,GO:0006888; GO:0005794; GO:0030008; GO:0005801; GO:0005783,ER to Golgi vesicle-mediated transport; Golgi apparatus; TRAPP complex; cis-Golgi network; endoplasmic reticulum,PF04099;,,,3.00E-76,ruditapes_c16163,,,,,TPPC1_RAT,Rattus norvegicus (Rat),ER to Golgi vesicle-mediated transport [GO:0006888] comp137147_c0_seq1,2185,40.2288,0.43981584,658,4642,,0,Q9NVU7,Protein SDA1 homolog (Nucleolar protein 130) (SDA1 domain-containing protein 1) (hSDA),Protein SDA1 homolog (Nucleolar protein 130) (SDA1 domain-containing protein 1) (hSDA),GO:0030036; GO:0005730; GO:0015031; GO:0042273; GO:0000055,actin cytoskeleton organization; nucleolus; protein transport; ribosomal large subunit biogenesis; ribosomal large subunit export from nucleus,PF08158;PF05285;,1.00E-176,CHOYP_SDA1.1.1,,,,,,,SDA1_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; protein transport [GO:0015031]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055] comp137149_c0_seq2,2332,38.2504,1.08426683,732,8,,4.00E-09,C9JTQ0,Ankyrin repeat domain-containing protein 63,Ankyrin repeat domain-containing protein 63,,,PF12796;,,,,,,,,,ANR63_HUMAN,Homo sapiens (Human), comp137152_c0_seq2,1103,40.6165,0.55494164,34,92,,7.00E-20,Q5TAX3,Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11),Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11),GO:0031123; GO:0050265; GO:0001816; GO:0005737; GO:0070102; GO:0010587; GO:0032088; GO:0003676; GO:0005730; GO:0032755; GO:0031054; GO:0031664; GO:0019827; GO:0008270,RNA 3'-end processing; RNA uridylyltransferase activity; cytokine production; cytoplasm; interleukin-6-mediated signaling pathway; miRNA catabolic process; negative regulation of NF-kappaB transcription factor activity; nucleic acid binding; nucleolus; positive regulation of interleukin-6 production; pre-miRNA processing; regulation of lipopolysaccharide-mediated signaling pathway; stem cell maintenance; zinc ion binding,PF01909;PF03828;PF00098;,,,,,,,,,TUT4_HUMAN,Homo sapiens (Human),miRNA catabolic process [GO:0010587]; miRNA metabolic process [GO:0010586]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]; stem cell population maintenance [GO:0019827] comp137166_c1_seq1,1000,47.7,0.61735745,17,6,,1.00E-80,Q8BQM9,Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09497;PF12145;PF12144;,4.00E-47,CHOYP_MD12L.1.1,,,,,,,MD12L_MOUSE,Mus musculus (Mouse), comp137166_c1_seq2,983,47.4059,0.61698542,11,30,,4.00E-55,Q9VW47,Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230),Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230),GO:0001104; GO:0022416; GO:0048749; GO:0036011; GO:0016592; GO:0030177; GO:0045498; GO:0006367,RNA polymerase II transcription cofactor activity; chaeta development; compound eye development; imaginal disc-derived leg segmentation; mediator complex; positive regulation of Wnt receptor signaling pathway; sex comb development; transcription initiation from RNA polymerase II promoter,PF09497;PF12145;,2.00E-38,CHOYP_MD12L.1.1,,,,,,,MED12_DROME,Drosophila melanogaster (Fruit fly),chaeta development [GO:0022416]; compound eye development [GO:0048749]; ecdysone-mediated induction of salivary gland cell autophagic cell death [GO:0035072]; imaginal disc-derived leg segmentation [GO:0036011]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sex comb development [GO:0045498]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp137167_c0_seq1,1733,41.431,0.60863481,0,0,,5.00E-131,P49354,Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),GO:0004662; GO:0043014; GO:0006921; GO:0005829; GO:0005875; GO:0008017; GO:0090045; GO:0090044; GO:0018343; GO:0004660; GO:0018344; GO:0004661; GO:0022400; GO:0016056; GO:0007179,CAAX-protein geranylgeranyltransferase activity; alpha-tubulin binding; cellular component disassembly involved in execution phase of apoptosis; cytosol; microtubule associated complex; microtubule binding; positive regulation of deacetylase activity; positive regulation of tubulin deacetylation; protein farnesylation; protein farnesyltransferase activity; protein geranylgeranylation; protein geranylgeranyltransferase activity; regulation of rhodopsin mediated signaling pathway; rhodopsin mediated signaling pathway; transforming growth factor beta receptor signaling pathway,PF01239;,,,,,,,,,FNTA_HUMAN,Homo sapiens (Human),cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; neurotransmitter receptor metabolic process [GO:0045213]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp137167_c0_seq3,2040,39.0686,0.5813344,0,0,,7.00E-49,O60052,Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),GO:0004662; GO:0005953; GO:0004663; GO:0034411; GO:0005634; GO:0004660; GO:0018344; GO:0006612,CAAX-protein geranylgeranyltransferase activity; CAAX-protein geranylgeranyltransferase complex; Rab geranylgeranyltransferase activity; cell wall (1->3)-beta-D-glucan biosynthetic process; nucleus; protein farnesyltransferase activity; protein geranylgeranylation; protein targeting to membrane,PF01239;,,,,,,,,,FNTA_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; protein targeting to plasma membrane [GO:0072661] comp137167_c0_seq5,1010,46.5347,0.76387735,0,0,,4.00E-135,P49354,Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),GO:0004662; GO:0043014; GO:0006921; GO:0005829; GO:0005875; GO:0008017; GO:0090045; GO:0090044; GO:0018343; GO:0004660; GO:0018344; GO:0004661; GO:0022400; GO:0016056; GO:0007179,CAAX-protein geranylgeranyltransferase activity; alpha-tubulin binding; cellular component disassembly involved in execution phase of apoptosis; cytosol; microtubule associated complex; microtubule binding; positive regulation of deacetylase activity; positive regulation of tubulin deacetylation; protein farnesylation; protein farnesyltransferase activity; protein geranylgeranylation; protein geranylgeranyltransferase activity; regulation of rhodopsin mediated signaling pathway; rhodopsin mediated signaling pathway; transforming growth factor beta receptor signaling pathway,PF01239;,4.00E-91,CHOYP_FNTA.1.1,,,,,,,FNTA_HUMAN,Homo sapiens (Human),cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; neurotransmitter receptor metabolic process [GO:0045213]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp137167_c0_seq9,2027,39.1712,0.58192267,0,0,,5.00E-69,O24304,Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha),GO:0004662; GO:0004660; GO:0018342,CAAX-protein geranylgeranyltransferase activity; protein farnesyltransferase activity; protein prenylation,PF01239;,8.00E-91,CHOYP_FNTA.1.1,,,,,,,FNTA_PEA,Pisum sativum (Garden pea),protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344] comp137169_c0_seq1,1822,41.8222,0.47094446,0,0,,1.00E-154,Q5XI42,Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5),Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5),GO:0004030; GO:0006081; GO:0005829; GO:0006068; GO:0005886,aldehyde dehydrogenase [NAD(P)+] activity; cellular aldehyde metabolic process; cytosol; ethanol catabolic process; plasma membrane,PF00171;,,,,,,,,,AL3B1_RAT,Rattus norvegicus (Rat),cellular aldehyde metabolic process [GO:0006081]; ethanol catabolic process [GO:0006068] comp137169_c0_seq2,1809,42.0674,0.48195656,5,11,,6.00E-155,Q5XI42,Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5),Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5),GO:0004030; GO:0006081; GO:0005829; GO:0006068; GO:0005886,aldehyde dehydrogenase [NAD(P)+] activity; cellular aldehyde metabolic process; cytosol; ethanol catabolic process; plasma membrane,PF00171;,8.00E-27,CHOYP_LOC100168209.1.1,,,,,,,AL3B1_RAT,Rattus norvegicus (Rat),cellular aldehyde metabolic process [GO:0006081]; ethanol catabolic process [GO:0006068] comp137169_c0_seq3,1559,42.5914,0.47089405,0,0,,4.00E-152,P51648,Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 10) (Aldehyde dehydrogenase family 3 member A2) (Microsomal aldehyde dehydrogenase),Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 10) (Aldehyde dehydrogenase family 3 member A2) (Microsomal aldehyde dehydrogenase),GO:0004029; GO:0004030; GO:0006081; GO:0007417; GO:0005789; GO:0008544; GO:0016021; GO:0043231; GO:0046577; GO:0050061; GO:0052814; GO:0005743; GO:0007422; GO:0005777; GO:0033306; GO:0006714,aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; cellular aldehyde metabolic process; central nervous system development; endoplasmic reticulum membrane; epidermis development; integral to membrane; intracellular membrane-bounded organelle; long-chain-alcohol oxidase activity; long-chain-aldehyde dehydrogenase activity; medium-chain-aldehyde dehydrogenase activity; mitochondrial inner membrane; peripheral nervous system development; peroxisome; phytol metabolic process; sesquiterpenoid metabolic process,PF00171;,,,,,,,,,AL3A2_HUMAN,Homo sapiens (Human),cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; formaldehyde metabolic process [GO:0046292]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; response to reactive oxygen species [GO:0000302]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148] comp137169_c0_seq6,1179,39.6947,0.37378677,0,0,,1.00E-79,P30907,"Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1) (Corneal 15.8 kDa protein) (Corneal protein 54) (bCP54) (Transparentin) (Fragment)","Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1) (Corneal 15.8 kDa protein) (Corneal protein 54) (bCP54) (Transparentin) (Fragment)",GO:0004030; GO:0006081; GO:0005737,aldehyde dehydrogenase [NAD(P)+] activity; cellular aldehyde metabolic process; cytoplasm,PF00171;,,,1.00E-13,ruditapes_c18905,,,,,AL3A1_BOVIN,Bos taurus (Bovine), comp137170_c0_seq2,1403,42.6942,0.44121161,134,1386,,2.00E-148,Q3SWZ4,Exosome complex component RRP45 (Exosome component 9),Exosome complex component RRP45 (Exosome component 9),GO:0003723; GO:0005737; GO:0000178; GO:0005730; GO:0006364,RNA binding; cytoplasm; exosome (RNase complex); nucleolus; rRNA processing,PF01138;PF03725;,2.00E-102,CHOYP_LOC100082337.1.1,,,,,,,EXOS9_BOVIN,Bos taurus (Bovine),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" comp137172_c0_seq1,505,42.5743,0.18175359,6,53,,4.00E-25,P11260,Putative transposase element L1Md-A101/L1Md-A102/L1Md-A2,LINE-1 retrotransposable element ORF1 protein (L1ORF1p) (LINE retrotransposable element 1) (LINE1 retrotransposable element 1) (Transposase element L1Md-A101/L1Md-A102/L1Md-A2),GO:0003723,RNA binding,PF02994;,,,,,,,,,TR22_MOUSE,Mus musculus (Mouse), comp137172_c0_seq2,485,41.4433,0.19459542,3,62,,3.00E-26,P11260,Putative transposase element L1Md-A101/L1Md-A102/L1Md-A2,LINE-1 retrotransposable element ORF1 protein (L1ORF1p) (LINE retrotransposable element 1) (LINE1 retrotransposable element 1) (Transposase element L1Md-A101/L1Md-A102/L1Md-A2),GO:0003723,RNA binding,PF02994;,,,,,,,,,TR22_MOUSE,Mus musculus (Mouse), comp137174_c0_seq4,3095,35.7997,0.48581857,32,18,,0,Q6PD03,Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha),Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha),GO:0031430; GO:0030018; GO:0000775; GO:0016020; GO:0090005; GO:0090219; GO:0005634; GO:0035307; GO:0000159; GO:0008601; GO:0007165,"M band; Z disc; chromosome, centromeric region; membrane; negative regulation of establishment of protein localization to plasma membrane; negative regulation of lipid kinase activity; nucleus; positive regulation of protein dephosphorylation; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; signal transduction",PF01603;,0,CHOYP_LOC100741406.1.1,1.00E-177,ruditapes2_c2225,,,,,2A5A_MOUSE,Mus musculus (Mouse),beta-catenin destruction complex disassembly [GO:1904886]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of lipid kinase activity [GO:0090219]; positive regulation of protein dephosphorylation [GO:0035307] comp137174_c0_seq5,1220,38.1967,0.47356205,4,0,,2.00E-46,Q28654,Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon) (Fragment),Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon) (Fragment),GO:0005737; GO:0043231; GO:0000159; GO:0008601; GO:0007165,cytoplasm; intracellular membrane-bounded organelle; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; signal transduction,PF01603;,0,CHOYP_LOC100741406.1.1,0,ruditapes_c28056,,,,,2A5E_RABIT,Oryctolagus cuniculus (Rabbit),signal transduction [GO:0007165] comp137176_c0_seq1,1266,44.2338,0.89085993,9,1541,female>male,6.00E-07,H3BS89,Transmembrane protein 178B,Transmembrane protein 178B,GO:0016021,integral to membrane,PF13903;,,,,,,,,,T178B_HUMAN,Homo sapiens (Human), comp137178_c0_seq4,620,39.0323,0.59580747,0,0,,9.00E-20,Q96NJ6,Zinc finger protein 3 homolog (Zfp-3) (Zinc finger protein 752),Zinc finger protein 3 homolog (Zfp-3) (Zinc finger protein 752),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZFP3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137178_c0_seq5,1623,40.9119,0.53164577,0,0,,2.00E-18,Q9NPC7,Myoneurin (Zinc finger and BTB domain-containing protein 31),Myoneurin (Zinc finger and BTB domain-containing protein 31),GO:0003677; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp137178_c0_seq6,1892,41.8605,0.65760052,0,0,,4.00E-10,Q96C55,Zinc finger protein 524,Zinc finger protein 524,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZN524_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137178_c0_seq7,889,41.6198,0.85165025,0,0,,1.00E-16,Q8IY51,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_HUMAN,Homo sapiens (Human), comp137182_c0_seq2,1093,44.7392,0.53188752,1,52,,4.00E-123,Q5ZLR1,Protein wntless homolog (Integral membrane protein GPR177),Protein wntless homolog (Integral membrane protein GPR177),GO:0000139; GO:0016055; GO:0030659; GO:0016021; GO:0007275,Golgi membrane; Wnt receptor signaling pathway; cytoplasmic vesicle membrane; integral to membrane; multicellular organismal development,,4.00E-91,CHOYP_WLS.1.1,,,,,,,WLS_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275]; positive regulation of Wnt protein secretion [GO:0061357]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055] comp137185_c0_seq4,1456,47.4588,0.45182481,53,0,,5.00E-22,Q8C5S7,Meiotic recombination protein REC8 homolog (Cohesin Rec8p),Meiotic recombination protein REC8 homolog (Cohesin Rec8p),GO:0007059; GO:0000778; GO:0000724; GO:0009566; GO:0000800; GO:0030999; GO:0001673; GO:0007141; GO:0034991; GO:0005654; GO:0001556; GO:0072520; GO:0007286,chromosome segregation; condensed nuclear chromosome kinetochore; double-strand break repair via homologous recombination; fertilization; lateral element; linear element assembly; male germ cell nucleus; male meiosis I; nuclear meiotic cohesin complex; nucleoplasm; oocyte maturation; seminiferous tubule development; spermatid development,PF04824;PF04825;,,,,,,,,,REC8_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; fertilization [GO:0009566]; male meiosis I [GO:0007141]; meiotic nuclear division [GO:0007126]; oocyte maturation [GO:0001556]; seminiferous tubule development [GO:0072520]; spermatid development [GO:0007286]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130] comp137187_c1_seq5,939,31.5229,0.68713528,2,4,,,,,,,,,9.00E-17,CHOYP_LOC101242709.1.1,8.00E-28,ruditapes_c25537,,,,,,, comp137189_c0_seq1,387,39.7933,0.61915307,53,85,,9.00E-07,P06101,Hsp90 co-chaperone Cdc37 (Cell division control protein 37) (Hsp90 chaperone protein kinase-targeting subunit),Hsp90 co-chaperone Cdc37 (Cell division control protein 37) (Hsp90 chaperone protein kinase-targeting subunit),GO:0000161; GO:0051301; GO:0005737; GO:0050821; GO:0051726; GO:0032872; GO:0007103; GO:0051082,MAPK cascade involved in osmosensory signaling pathway; cell division; cytoplasm; protein stabilization; regulation of cell cycle; regulation of stress-activated MAPK cascade; spindle pole body duplication associated with nuclear envelope; unfolded protein binding,PF08564;PF08565;PF03234;,,,,,,,,,CDC37_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cell division [GO:0051301]; MAPK cascade involved in osmosensory signaling pathway [GO:0000161]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of stress-activated MAPK cascade [GO:0032872]; spindle pole body duplication [GO:0030474] comp137189_c1_seq1,995,42.3116,0.5782299,214,367,,3.00E-89,Q9DGQ7,Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37),Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37),GO:0005737,cytoplasm,PF08564;PF08565;PF03234;,2.00E-49,CHOYP_BRAFLDRAFT_115687.1.1,,,,,,,CDC37_TETFL,Tetraodon fluviatilis (Green pufferfish) (Chelonodon fluviatilis), comp137192_c0_seq1,1131,40.672,0.63204963,137,383,,8.00E-129,P29054,Transcription initiation factor IIB (General transcription factor TFIIB),Transcription initiation factor IIB (General transcription factor TFIIB),GO:0006352; GO:0005634; GO:0006355; GO:0008270,"DNA-dependent transcription, initiation; nucleus; regulation of transcription, DNA-dependent; zinc ion binding",PF08271;PF00382;,2.00E-120,CHOYP_TF2B.1.1,1.00E-83,ruditapes_c7235,,,,,TF2B_XENLA,Xenopus laevis (African clawed frog),"DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]" comp137193_c0_seq1,1781,36.0472,0.45747815,359,1517,,4.00E-06,Q8WV60,"Pentatricopeptide repeat-containing protein 2, mitochondrial","Pentatricopeptide repeat-containing protein 2, mitochondrial",GO:0001822; GO:0001889; GO:0006397; GO:0005739; GO:0007005; GO:0048747; GO:0050684; GO:0055010,kidney development; liver development; mRNA processing; mitochondrion; mitochondrion organization; muscle fiber development; regulation of mRNA processing; ventricular cardiac muscle tissue morphogenesis,PF10037;,,,,,,,,,PTCD2_HUMAN,Homo sapiens (Human),kidney development [GO:0001822]; liver development [GO:0001889]; mitochondrion organization [GO:0007005]; mRNA processing [GO:0006397]; muscle fiber development [GO:0048747]; regulation of mRNA processing [GO:0050684]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] comp137195_c0_seq3,1336,39.8952,0.60564571,13,3,,4.00E-80,Q5RBN9,Transcriptional adapter 2-beta,Transcriptional adapter 2-beta,GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00249;,7.00E-20,CHOYP_NEMVEDRAFT_V1G222546.1.1,1.00E-70,ruditapes_c3401,,,,,TAD2B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137195_c0_seq5,1794,40.4682,0.59851911,3,0,,,,,,,,,4.00E-100,CHOYP_LOC100893166.1.2,1.00E-168,ruditapes2_c2264,,,,,,, comp137195_c0_seq6,1485,40.7407,0.56732868,0,0,,,,,,,,,1.00E-17,CHOYP_LOC100893166.2.2,,,,,,,,, comp137196_c0_seq1,2567,39.3455,0.44357505,117,613,,3.00E-55,P56182,Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein),Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein),GO:0005730; GO:0030688; GO:0006364,"nucleolus; preribosome, small subunit precursor; rRNA processing",PF05997;,,,,,,,,,RRP1_HUMAN,Homo sapiens (Human),rRNA processing [GO:0006364] comp137198_c0_seq1,2658,45.0715,0.30405951,0,0,,3.00E-46,Q5K6N0,Transmembrane protein 232 (Testis-specific protein 13),Transmembrane protein 232 (Testis-specific protein 13),GO:0016021,integral to membrane,PF15877;,1.00E-146,CHOYP_BRAFLDRAFT_104097.1.1,,,,,,,TM232_MOUSE,Mus musculus (Mouse), comp137198_c0_seq2,2679,44.9421,0.30338594,0,0,,1.00E-48,C9JQI7,Transmembrane protein 232,Transmembrane protein 232,GO:0016021,integral to membrane,PF15877;,1.00E-146,CHOYP_BRAFLDRAFT_104097.1.1,,,,,,,TM232_HUMAN,Homo sapiens (Human), comp137198_c0_seq3,3363,41.2727,0.33601711,0,0,,8.00E-46,Q5K6N0,Transmembrane protein 232 (Testis-specific protein 13),Transmembrane protein 232 (Testis-specific protein 13),GO:0016021,integral to membrane,PF15877;,,,,,,,,,TM232_MOUSE,Mus musculus (Mouse), comp137198_c0_seq4,3384,41.1939,0.33515891,0,0,,5.00E-48,C9JQI7,Transmembrane protein 232,Transmembrane protein 232,GO:0016021,integral to membrane,PF15877;,,,,,,,,,TM232_HUMAN,Homo sapiens (Human), comp137199_c0_seq3,1564,40.0256,0.4963478,1,51,,3.00E-34,A4IHY1,Proteasome assembly chaperone 1,Proteasome assembly chaperone 1,GO:0005783; GO:0043248,endoplasmic reticulum; proteasome assembly,PF16094;,,,,,,,,,PSMG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),proteasome assembly [GO:0043248]; proteasome core complex assembly [GO:0080129] comp137199_c0_seq7,1754,36.203,0.66164674,0,23,,4.00E-34,A4IHY1,Proteasome assembly chaperone 1,Proteasome assembly chaperone 1,GO:0005783; GO:0043248,endoplasmic reticulum; proteasome assembly,PF16094;,2.00E-14,CHOYP_BRAFLDRAFT_81733.1.1,,,,,,,PSMG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),proteasome assembly [GO:0043248]; proteasome core complex assembly [GO:0080129] comp137200_c0_seq1,1584,37.8788,0.55183706,141,848,,1.00E-68,Q96E29,"mTERF domain-containing protein 1, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3)","Transcription termination factor 3, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3) (mTERF domain-containing protein 1, mitochondrial)",GO:0005739; GO:0045892; GO:0044212; GO:0006351,"mitochondrion; negative regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF02536;,,,,,,,,,MTER1_HUMAN,Homo sapiens (Human),"macroautophagy [GO:0016236]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp137201_c0_seq1,1615,42.4768,1.00579808,25,313,,3.00E-127,Q5VYY2,Lipase member M (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 3),Lipase member M (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 3),GO:0005576; GO:0016788; GO:0016042,"extracellular region; hydrolase activity, acting on ester bonds; lipid catabolic process",PF00561;,,,1.00E-15,ruditapes_c26423,,,,,LIPM_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241] comp137210_c0_seq1,1332,37.7628,0.4251996,167,1113,,2.00E-13,Q6GR66,Mitochondrial import inner membrane translocase subunit Tim10 B (Mitochondrial import inner membrane translocase subunit Tim9 B),Mitochondrial import inner membrane translocase subunit Tim10 B (Mitochondrial import inner membrane translocase subunit Tim9 B),GO:0046872; GO:0005743; GO:0015031,metal ion binding; mitochondrial inner membrane; protein transport,PF02953;,,,,,,,,,TIM9B_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp137214_c0_seq1,1282,36.8175,0.55577772,92,624,,3.00E-51,Q24K03,THUMP domain-containing protein 1,THUMP domain-containing protein 1,GO:0003723,RNA binding,PF02926;,2.00E-26,CHOYP_THUM1.1.1,,,,,,,THUM1_BOVIN,Bos taurus (Bovine), comp137216_c1_seq1,1158,50,0.41487717,25,24,,4.00E-61,Q62920,PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein),PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein),GO:0030018; GO:0003779; GO:0042805; GO:0030054; GO:0005829; GO:0007507; GO:0016020; GO:0043005; GO:0014069; GO:0045211; GO:0047485; GO:0005080; GO:0030159; GO:0061001; GO:0051963; GO:0008270,Z disc; actin binding; actinin binding; cell junction; cytosol; heart development; membrane; neuron projection; postsynaptic density; postsynaptic membrane; protein N-terminus binding; protein kinase C binding; receptor signaling complex scaffold activity; regulation of dendritic spine morphogenesis; regulation of synapse assembly; zinc ion binding,PF15936;PF00412;PF00595;,,,,,,,,,PDLI5_RAT,Rattus norvegicus (Rat),cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963] comp137216_c1_seq2,1069,50.9822,0.25956896,32,53,,1.00E-71,A1ZA47,PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),GO:0030018; GO:0015629; GO:0051371; GO:0005927; GO:0030239; GO:0001952; GO:0008270,Z disc; actin cytoskeleton; muscle alpha-actinin binding; muscle tendon junction; myofibril assembly; regulation of cell-matrix adhesion; zinc ion binding,PF15936;PF00412;PF00595;,1.00E-97,CHOYP_contig_009176,,,,,,,ZASP_DROME,Drosophila melanogaster (Fruit fly),muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952] comp137216_c1_seq4,460,44.5652,0.57647444,4,0,,3.00E-16,Q3SYZ8,PDZ and LIM domain protein 3,PDZ and LIM domain protein 3,GO:0030018; GO:0015629; GO:0007015; GO:0007507; GO:0008307; GO:0008270,Z disc; actin cytoskeleton; actin filament organization; heart development; structural constituent of muscle; zinc ion binding,PF15936;PF00412;PF00595;,,,,,,,,,PDLI3_BOVIN,Bos taurus (Bovine),actin filament organization [GO:0007015]; heart development [GO:0007507] comp137221_c1_seq1,1366,32.284,0.5173243,166,630,,,,,,,,,2.00E-14,CHOYP_contig_034086,,,,,,,,, comp137230_c0_seq1,1880,39.0426,0.34316217,18,159,,2.00E-120,Q91VS8,"FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)","FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)",GO:0030676; GO:0016601; GO:0031532; GO:0007155; GO:0005856; GO:0005829; GO:0019898; GO:0016322; GO:0030316; GO:0005543; GO:0071800; GO:0035023; GO:0033623; GO:0071526,Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; actin cytoskeleton reorganization; cell adhesion; cytoskeleton; cytosol; extrinsic to membrane; neuron remodeling; osteoclast differentiation; phospholipid binding; podosome assembly; regulation of Rho protein signal transduction; regulation of integrin activation; semaphorin-plexin signaling pathway,PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;,7.00E-174,CHOYP_FARP2.1.1,,,,,,,FARP2_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526] comp137230_c0_seq4,541,44.5471,0.5620871,7,57,,5.00E-55,O94887,"FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)","FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)",GO:0030676; GO:0016601; GO:0031532; GO:0007411; GO:0007155; GO:0005856; GO:0005829; GO:0019898; GO:0016322; GO:0030316; GO:0005543; GO:0071800; GO:0035023; GO:0033623; GO:0071526,Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; actin cytoskeleton reorganization; axon guidance; cell adhesion; cytoskeleton; cytosol; extrinsic to membrane; neuron remodeling; osteoclast differentiation; phospholipid binding; podosome assembly; regulation of Rho protein signal transduction; regulation of integrin activation; semaphorin-plexin signaling pathway,PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;,,,,,,,,,FARP2_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526] comp137231_c0_seq1,776,40.9794,0.51990719,53,430,,1.00E-66,Q5RDK5,Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37),Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37),GO:0005737; GO:0006782; GO:0004853,cytoplasm; protoporphyrinogen IX biosynthetic process; uroporphyrinogen decarboxylase activity,PF01208;,6.00E-37,CHOYP_DCUP.1.1,,,,,,,DCUP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protoporphyrinogen IX biosynthetic process [GO:0006782] comp137231_c0_seq2,564,46.8085,0.39354663,21,150,,7.00E-69,O18601,Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37),Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37),GO:0005737; GO:0006782; GO:0004853,cytoplasm; protoporphyrinogen IX biosynthetic process; uroporphyrinogen decarboxylase activity,PF01208;,,,,,,,,,DCUP_DROVI,Drosophila virilis (Fruit fly),protoporphyrinogen IX biosynthetic process [GO:0006782] comp137239_c0_seq1,315,43.4921,1.09060633,6,35,,1.00E-13,P21369,Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase),Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase),GO:0008936; GO:0019363,nicotinamidase activity; pyridine nucleotide biosynthetic process,PF00857;,,,,,,,,,PNCA_ECOLI,Escherichia coli (strain K12),NAD metabolic process [GO:0019674]; nicotinamide metabolic process [GO:0006769]; pyridine nucleotide biosynthetic process [GO:0019363] comp137239_c3_seq1,480,47.7083,0.44067988,12,19,,5.00E-20,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp137240_c0_seq1,1947,39.3939,0.42963097,152,414,,1.00E-13,Q923A2,Protein Spindly (Coiled-coil domain-containing protein 99) (Spindle apparatus coiled-coil domain-containing protein 1),Protein Spindly (Coiled-coil domain-containing protein 99) (Spindle apparatus coiled-coil domain-containing protein 1),GO:0051301; GO:0000940; GO:0005737; GO:0000132; GO:0043515; GO:0005815; GO:0007080; GO:0005634; GO:0034501; GO:0000922,cell division; condensed chromosome outer kinetochore; cytoplasm; establishment of mitotic spindle orientation; kinetochore binding; microtubule organizing center; mitotic metaphase plate congression; nucleus; protein localization to kinetochore; spindle pole,,,,,,,,,,SPDLY_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic metaphase plate congression [GO:0007080]; protein localization to kinetochore [GO:0034501]; spindle checkpoint [GO:0031577] comp137242_c0_seq1,1009,39.5441,0.40849383,78,450,,3.00E-58,Q6W8P9,Aldo-keto reductase family 1 member C23-like protein (EC 1.1.1.-) (Putative prostaglandin F synthase),Aldo-keto reductase family 1 member C23-like protein (EC 1.1.1.-) (Putative prostaglandin F synthase),GO:0005737; GO:0016491; GO:0008202,cytoplasm; oxidoreductase activity; steroid metabolic process,PF00248;,,,,,,,,,AK1CO_HORSE,Equus caballus (Horse),steroid metabolic process [GO:0008202] comp137243_c0_seq6,1113,39.8023,0.27320684,0,0,,1.00E-10,Q9HCI6,Uncharacterized protein KIAA1586,E3 SUMO-protein ligase KIAA1586 (EC 6.3.2.-),GO:0003676,nucleic acid binding,,,,,,,,,,K1586_HUMAN,Homo sapiens (Human),protein sumoylation [GO:0016925] comp137243_c0_seq7,1077,38.8115,0.39518879,0,0,,4.00E-08,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137246_c1_seq1,1969,41.7471,0.79307589,0,0,,0,Q03342,Actin-3 (Fragment),Actin-3 (Fragment),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_LOC100890099.1.1,,,,,,,ACT3_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp137246_c1_seq10,1878,43.6635,0.81680594,0,0,,,,,,,,,0,CHOYP_ACT.10.27,0,ruditapes2_lrc3213,,,,,,, comp137246_c1_seq11,1914,40.8046,0.49027151,0,0,,2.00E-122,Q7ZTP2,Actin-related protein 2-A (Actin-like protein 2-A),Actin-related protein 2-A (Actin-like protein 2-A),GO:0005524; GO:0034314; GO:0005885; GO:0042995; GO:0005737,ATP binding; Arp2/3 complex-mediated actin nucleation; Arp2/3 protein complex; cell projection; cytoplasm,PF00022;,0,CHOYP_ACT1.4.7,,,,,,,ARP2A_XENLA,Xenopus laevis (African clawed frog),Arp2/3 complex-mediated actin nucleation [GO:0034314] comp137246_c1_seq12,1894,41.2355,0.6838105,1,0,,0,P02582,Actin-1,Actin-1,GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT3.2.3,0,ruditapes_lrc28735,,,,,ACT1_MAIZE,Zea mays (Maize), comp137246_c1_seq13,1985,39.5466,0.63180258,445,2429,,0,P18603,"Actin, clone 403","Actin, clone 403",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,2.00E-131,CHOYP_NEMVEDRAFT_V1G169611.1.1,,,,,,,ACT4_ARTSX,Artemia sp. (Brine shrimp), comp137246_c1_seq14,1898,43.2561,0.66541372,0,0,,0,Q92193,Actin (Fragment),Actin (Fragment),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_LOC100890099.1.1,,,,,,,ACT_CRAVI,Crassostrea virginica (Eastern oyster), comp137246_c1_seq15,1918,44.6298,0.74541009,0,0,,0,P12431,"Actin, muscle","Actin, muscle",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.10.27,1.00E-155,ruditapes_c19045,,,,,ACTM_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp137246_c1_seq16,1898,44.942,0.90557965,0,0,,0,Q26065,"Actin, adductor muscle","Actin, adductor muscle",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.3.27,2.00E-177,ruditapes_c4412,,,,,ACT_PLAMG,Placopecten magellanicus (Sea scallop), comp137246_c1_seq17,1458,46.6392,0.70876885,0,0,,0,Q03342,Actin-3 (Fragment),Actin-3 (Fragment),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_LOC100890099.1.1,4.00E-91,ruditapes2_c396,,,,,ACT3_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp137246_c1_seq18,1969,42.8136,0.76613968,0,0,,1.00E-85,P86700,"Actin, muscle (Alpha-actin) (Fragments)","Actin, muscle (Alpha-actin) (Fragments)",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_CYIIB.1.2,4.00E-54,ruditapes_c713,,,,,ACT_CHIOP,Chionoecetes opilio (Crab-beetle), comp137246_c1_seq19,1478,47.023,0.82697449,0,0,,0,Q26065,"Actin, adductor muscle","Actin, adductor muscle",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT2.1.3,1.00E-34,ruditapes_c5307,,,,,ACT_PLAMG,Placopecten magellanicus (Sea scallop), comp137246_c1_seq2,1894,43.0306,0.85784929,16,82,,0,P10983,,,,,,0,CHOYP_ACT.8.27,,,,,,,ACT1_CAEEL,, comp137246_c1_seq20,1878,44.6219,0.80605976,0,0,,0,P84856,"Actin, cytoplasmic 1 (Beta-actin)","Actin, cytoplasmic 1 (Beta-actin)",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.10.27,0,ruditapes_c127,,,,,ACTB_CERPY,Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus), comp137246_c1_seq21,1458,43.8957,0.55567952,0,0,,0,P30172,Actin-100 (Fragment),Actin-100 (Fragment),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.19.27,0,ruditapes_c2218,,,,,ACT12_SOLTU,Solanum tuberosum (Potato), comp137246_c1_seq22,1878,42.066,0.66237897,0,0,,0,Q55EU6,Putative actin-23,Putative actin-23,GO:0005524; GO:0015629; GO:0000902; GO:0017022; GO:0045335; GO:0005200,ATP binding; actin cytoskeleton; cell morphogenesis; myosin binding; phagocytic vesicle; structural constituent of cytoskeleton,PF00022;,0,CHOYP_ACTC.3.6,0,ruditapes2_lrc2178,,,,,ACT23_DICDI,Dictyostelium discoideum (Slime mold), comp137246_c1_seq23,1898,41.7808,0.48411164,0,0,,5.00E-121,Q7ZTP2,Actin-related protein 2-A (Actin-like protein 2-A),Actin-related protein 2-A (Actin-like protein 2-A),GO:0005524; GO:0034314; GO:0005885; GO:0042995; GO:0005737,ATP binding; Arp2/3 complex-mediated actin nucleation; Arp2/3 protein complex; cell projection; cytoplasm,PF00022;,0,CHOYP_ACT.19.27,0,ruditapes_lrc10071,,,,,ARP2A_XENLA,Xenopus laevis (African clawed frog),Arp2/3 complex-mediated actin nucleation [GO:0034314] comp137246_c1_seq24,1898,44.3098,0.64458844,0,0,,0,Q26065,"Actin, adductor muscle","Actin, adductor muscle",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.10.27,4.00E-48,ruditapes_s38992,7.00E-117,CF369133.p.cg.6,6,,ACT_PLAMG,Placopecten magellanicus (Sea scallop), comp137246_c1_seq25,1969,40.3758,0.61127451,0,0,,0,O93400,"Actin, cytoplasmic 1 (Beta-actin) (Cytoplasmic beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]","Actin, cytoplasmic 1 (Beta-actin) (Cytoplasmic beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,2.00E-131,CHOYP_NEMVEDRAFT_V1G169611.1.1,0,ruditapes2_c416,,,,,ACTB_XENLA,Xenopus laevis (African clawed frog), comp137246_c1_seq26,1458,45.4047,0.71921162,0,0,,0,P12716,"Actin, cytoplasmic","Actin, cytoplasmic",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_LOC101072885.1.1,0,ruditapes_lrc32388,3.00E-64,CU684679.p.cg.6,1,,ACTC_PISOC,Pisaster ochraceus (Ochre sea star) (Asterias ochracea), comp137246_c1_seq3,1914,42.372,0.68725688,0,0,,0,P12716,"Actin, cytoplasmic","Actin, cytoplasmic",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACTG.1.1,2.00E-20,ruditapes_lrc28223,,,,,ACTC_PISOC,Pisaster ochraceus (Ochre sea star) (Asterias ochracea), comp137246_c1_seq4,1989,43.1373,0.86872556,0,0,,0,Q26065,"Actin, adductor muscle","Actin, adductor muscle",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT1.1.7,1.00E-17,ruditapes_c29955,,,,,ACT_PLAMG,Placopecten magellanicus (Sea scallop), comp137246_c1_seq5,1985,41.1587,0.83315375,1015,5989,,0,Q7RPB4,Actin-2 (Actin II),Actin-2 (Actin II),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.24.27,,,,,,,ACT2_PLAYO,Plasmodium yoelii yoelii, comp137246_c1_seq6,1446,44.3292,0.80459506,2,3,,0,Q6NVA9,"Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]","Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT.10.27,0,ruditapes2_lrc3936,,,,,ACTB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp137246_c1_seq7,1474,44.2334,0.75016988,0,0,,0,P12716,"Actin, cytoplasmic","Actin, cytoplasmic",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_LOC101470738.2.2,2.00E-87,ruditapes_lrc34365,,,,,ACTC_PISOC,Pisaster ochraceus (Ochre sea star) (Asterias ochracea), comp137246_c1_seq8,1167,45.844,0.62044331,0,0,,1.00E-138,P30170,Actin-85C (Fragment),Actin-85C (Fragment),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_ACT2.1.3,4.00E-134,ruditapes_c2779,,,,,ACT10_SOLTU,Solanum tuberosum (Potato), comp137246_c1_seq9,1474,42.7408,0.57988938,72,351,,0,Q25010,"Actin, cytoplasmic A3a","Actin, cytoplasmic A3a",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,0,CHOYP_LOC752782.1.1,1.00E-153,ruditapes2_lrc4521,,,,,ACT3A_HELAM,Helicoverpa armigera (Cotton bollworm) (Heliothis armigera), comp137249_c0_seq1,2113,38.5234,0.78302019,145,9,,2.00E-99,A8WHP3,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,,,,,,,,,SC5A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),sodium ion transport [GO:0006814] comp137249_c0_seq2,1419,41.649,0.70051891,3,0,,2.00E-101,Q8VDT1,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (mSGLT4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (mSGLT4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,2.00E-77,CHOYP_SC5A9.3.5,,,,,,,SC5A9_MOUSE,Mus musculus (Mouse),sodium ion transport [GO:0006814] comp137250_c0_seq1,258,50.7752,0.85359098,3,93,,4.00E-06,P18699,Tubulin beta chain (Beta-tubulin) (Fragment),Tubulin beta chain (Beta-tubulin) (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF03953;,5.00E-38,CHOYP_TBA.1.6,5.00E-36,ruditapes_c2884,,,,,TBB_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),microtubule-based process [GO:0007017] comp137250_c0_seq2,1190,46.4706,1.07923014,80,893,,0,Q8WQ47,Tubulin alpha chain (allergen Lep d ?),Tubulin alpha chain (allergen Lep d ?),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_TBA3.1.1,1.00E-128,ruditapes2_c97,,,,,TBA_LEPDS,Lepidoglyphus destructor (Storage mite) (Glycyphagus destructor),microtubule-based process [GO:0007017] comp137250_c1_seq1,758,36.2797,0.96914406,5,32,,1.00E-09,Q08628,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization,,,,,,,,,,TBA_BLEJA,Blepharisma japonicum,microtubule-based process [GO:0007017] comp137250_c1_seq2,742,35.9838,0.96276231,6,95,,2.00E-11,P02553,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF03953;,8.00E-16,CHOYP_TUBA4A.1.1,6.00E-22,ruditapes_lrc38116,,,,,TBA_LYTPI,Lytechinus pictus (Painted sea urchin),microtubule-based process [GO:0007017] comp137251_c0_seq1,1324,43.5045,0.95428521,2,6,,8.00E-89,A1RYE4,Glyoxylate reductase (EC 1.1.1.26),Glyoxylate reductase (EC 1.1.1.26),GO:0051287; GO:0005737; GO:0047964,NAD binding; cytoplasm; glyoxylate reductase activity,PF00389;PF02826;,2.00E-14,CHOYP_LOC100375265.2.2,,,,,,,GYAR_THEPD,Thermofilum pendens (strain Hrk 5), comp137251_c0_seq2,869,47.5259,0.87866225,32,85,,7.00E-29,Q9P7Q1,2-hydroxyacid dehydrogenase homolog 2 (EC 1.1.1.-),2-hydroxyacid dehydrogenase homolog 2 (EC 1.1.1.-),GO:0051287; GO:0005829; GO:0005634; GO:0016616,"NAD binding; cytosol; nucleus; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF00389;PF02826;,,,,,,,,,DDH2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp137251_c0_seq3,1112,42.7158,0.86466195,8,41,,6.00E-108,Q91Z53,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0005737; GO:0007588; GO:0008465; GO:0030267; GO:0016618; GO:0051259,NAD binding; NADPH binding; cytoplasm; excretion; glycerate dehydrogenase activity; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; protein oligomerization,PF00389;PF02826;,,,,,,,,,GRHPR_MOUSE,Mus musculus (Mouse),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp137251_c0_seq4,1081,47.6411,0.94921127,1,0,,,,,,,,,2.00E-13,CHOYP_LOC100375265.2.2,3.00E-28,ruditapes_c25894,,,,,,, comp137252_c0_seq1,1921,47.0588,1.08521448,29,331,,1.00E-27,Q8BI06,Protein KIAA1199 homolog (Protein 12H19.01.T7),Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) (Protein 12H19.01.T7),GO:0005737,cytoplasm,PF10162;PF13330;,,,,,,,,,K1199_MOUSE,Mus musculus (Mouse),hyaluronan catabolic process [GO:0030214]; positive regulation of cell migration [GO:0030335]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; sensory perception of sound [GO:0007605] comp137253_c0_seq2,2574,42.3854,0.43641116,153,586,,0,Q3MHH4,Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS),Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS),GO:0005524; GO:0005737; GO:0004819; GO:0006425,ATP binding; cytoplasm; glutamine-tRNA ligase activity; glutaminyl-tRNA aminoacylation,PF00749;PF03950;PF04558;PF04557;,0,CHOYP_QARS.2.2,1.00E-80,ruditapes_lrc12879,,,,,SYQ_BOVIN,Bos taurus (Bovine),brain development [GO:0007420]; glutaminyl-tRNA aminoacylation [GO:0006425] comp137254_c0_seq1,1946,42.2919,0.53667875,272,265,,0,P40201,Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),GO:0005524; GO:0003677; GO:0006333; GO:0003682; GO:0006338; GO:0005737; GO:0004386; GO:0005634; GO:0006355; GO:0006351,"ATP binding; DNA binding; chromatin assembly or disassembly; chromatin binding; chromatin remodeling; cytoplasm; helicase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00385;PF13907;PF00271;PF00176;,0,CHOYP_CHD2.1.1,,,,,,,CHD1_MOUSE,Mus musculus (Mouse),"chromatin assembly or disassembly [GO:0006333]; chromatin remodeling [GO:0006338]; positive regulation by host of viral transcription [GO:0043923]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137256_c0_seq2,925,38.5946,0.47393056,22,41,,7.00E-08,Q9WUF3,CASP8-associated protein 2 (FLICE-associated huge protein),CASP8-associated protein 2 (FLICE-associated huge protein),GO:0003677; GO:0036337; GO:0016605; GO:0032184; GO:0007049; GO:0008656; GO:0008625; GO:0042802; GO:0005739; GO:0006355; GO:0003714; GO:0006351,"DNA binding; Fas signaling pathway; PML body; SUMO polymer binding; cell cycle; cysteine-type endopeptidase activator activity involved in apoptotic process; extrinsic apoptotic signaling pathway via death domain receptors; identical protein binding; mitochondrion; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",,,,,,,,,,C8AP2_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fas signaling pathway [GO:0036337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137268_c0_seq1,1169,37.8956,0.58064559,2228,8757,,3.00E-87,P0CB97,"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)","NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)",GO:0051539; GO:0008137; GO:0046872; GO:0005747; GO:0032981; GO:0006979,"4 iron, 4 sulfur cluster binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; mitochondrial respiratory chain complex I; mitochondrial respiratory chain complex I assembly; response to oxidative stress",PF12838;,1.00E-85,CHOYP_LOC100373694.1.1,1.00E-82,ruditapes2_c2109,,,,,NDUS8_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mitochondrial respiratory chain complex I assembly [GO:0032981]; response to oxidative stress [GO:0006979] comp137269_c0_seq1,1048,43.9885,0.47797104,66,96,,2.00E-18,Q6P2H3,Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21),Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21),GO:0005813; GO:0005737; GO:0005730; GO:0000922,centrosome; cytoplasm; nucleolus; spindle pole,,,,,,,,,,CEP85_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; regulation of mitotic centrosome separation [GO:0046602] comp137272_c0_seq1,2314,41.8755,1.16461622,0,0,,1.00E-38,P07152,Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transformation-associated protein 34A) (Transin-2),Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transformation-associated protein 34A) (Transin-2),GO:0005509; GO:0030574; GO:0004222; GO:0005578; GO:0006508; GO:0008270,calcium ion binding; collagen catabolic process; metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF00045;PF00413;PF01471;,,,,,,,,,MMP10_RAT,Rattus norvegicus (Rat),collagen catabolic process [GO:0030574] comp137272_c0_seq2,2286,41.8635,1.13935258,0,0,,5.00E-48,Q99542,Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18),Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18),GO:0001525; GO:0005509; GO:0030154; GO:0030574; GO:0022617; GO:0001554; GO:0004222; GO:0001541; GO:0001542; GO:0005578; GO:0006508; GO:0051591; GO:0009725; GO:0008270,angiogenesis; calcium ion binding; cell differentiation; collagen catabolic process; extracellular matrix disassembly; luteolysis; metalloendopeptidase activity; ovarian follicle development; ovulation from ovarian follicle; proteinaceous extracellular matrix; proteolysis; response to cAMP; response to hormone stimulus; zinc ion binding,PF00045;PF00413;PF01471;,,,3.00E-12,ruditapes_c6996,,,,,MMP19_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; proteolysis [GO:0006508]; response to cAMP [GO:0051591]; response to hormone [GO:0009725] comp137275_c0_seq2,1250,40.96,0.46290501,9,16,,3.00E-74,P83510,Traf2 and NCK-interacting protein kinase (EC 2.7.11.1),Traf2 and NCK-interacting protein kinase (EC 2.7.11.1),GO:0005524; GO:0016055; GO:0031532; GO:0007256; GO:0005856; GO:0005634; GO:0048471; GO:0046777; GO:0004674; GO:0055037; GO:0048814; GO:0005083,ATP binding; Wnt receptor signaling pathway; actin cytoskeleton reorganization; activation of JNKK activity; cytoskeleton; nucleus; perinuclear region of cytoplasm; protein autophosphorylation; protein serine/threonine kinase activity; recycling endosome; regulation of dendrite morphogenesis; small GTPase regulator activity,PF00780;PF00069;,0,CHOYP_LOC100864577.1.1,,,,,,,TNIK_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; activation of JNKK activity [GO:0007256]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; microvillus assembly [GO:0030033]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of dendrite morphogenesis [GO:0048814]; Wnt signaling pathway [GO:0016055]; xenophagy [GO:0098792] comp137275_c0_seq3,2071,43.8436,0.37220602,54,53,,2.00E-153,Q924I2,Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3),Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3),GO:0005524; GO:0007243; GO:0004674; GO:0009411; GO:0006950; GO:0005083,ATP binding; intracellular protein kinase cascade; protein serine/threonine kinase activity; response to UV; response to stress; small GTPase regulator activity,PF00780;PF00069;,,,,,,,,,M4K3_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; response to UV [GO:0009411] comp137275_c0_seq4,920,38.587,0.32198741,47,57,,,,,,,,,,,2.00E-16,ruditapes_c8601,,,,,,, comp137277_c0_seq3,3074,45.6083,0.70121866,107,412,,5.00E-71,Q8TDM6,Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),GO:0008013; GO:0005913; GO:0016337; GO:0005737; GO:0008092; GO:0035556; GO:0008285; GO:0005886; GO:0030159; GO:0042981,beta-catenin binding; cell-cell adherens junction; cell-cell adhesion; cytoplasm; cytoskeletal protein binding; intracellular signal transduction; negative regulation of cell proliferation; plasma membrane; receptor signaling complex scaffold activity; regulation of apoptotic process,PF00625;PF00595;PF04822;,5.00E-45,CHOYP_DLG5A.1.1,,,,,,,DLG5_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186] comp137277_c1_seq1,724,41.1602,0.9094094,13,30,,4.00E-32,Q8TDM6,Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),GO:0008013; GO:0005913; GO:0016337; GO:0005737; GO:0008092; GO:0035556; GO:0008285; GO:0005886; GO:0030159; GO:0042981,beta-catenin binding; cell-cell adherens junction; cell-cell adhesion; cytoplasm; cytoskeletal protein binding; intracellular signal transduction; negative regulation of cell proliferation; plasma membrane; receptor signaling complex scaffold activity; regulation of apoptotic process,PF00625;PF00595;PF04822;,,,,,,,,,DLG5_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186] comp137278_c0_seq1,483,47.412,1.20642362,6,92,,4.00E-17,Q9AJD6,Pyridoxine 4-oxidase (EC 1.1.3.12),Pyridoxine 4-oxidase (EC 1.1.3.12),GO:0006066; GO:0008812; GO:0050660; GO:0050237; GO:0042820,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding; pyridoxine 4-oxidase activity; vitamin B6 catabolic process,PF05199;PF00732;,,,,,,,,,PNO_MICLT,Microbacterium luteolum (Aureobacterium luteolum),vitamin B6 catabolic process [GO:0042820] comp137278_c1_seq1,1375,44.7273,1.14603896,62,397,,4.00E-97,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,2.00E-19,CHOYP_LOC100118063.4.4,2.00E-18,ruditapes_c10345,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp137280_c0_seq2,2166,34.0259,0.35984187,543,1558,,7.00E-18,Q23280,Uncharacterized protein ZC395.10,Co-chaperone protein daf-41 (Abnormal dauer formation protein daf-41) (p23/cytosolic prostaglandin E synthase 3 homolog),GO:0030016,myofibril,PF04969;,1.00E-18,CHOYP_LOC100377422.1.2,5.00E-98,ruditapes2_c521,,,,,YOCA_CAEEL,Caenorhabditis elegans, comp137281_c0_seq1,1068,35.0187,0.49369361,0,5,,1.00E-42,P79800,GTPase KRas (K-Ras 2) (Ki-Ras) (K-ras),GTPase KRas (K-Ras 2) (Ki-Ras) (K-ras),GO:0005525; GO:0003924; GO:0005886; GO:0007264,GTP binding; GTPase activity; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RASK_MELGA,Meleagris gallopavo (Common turkey),positive regulation of cell proliferation [GO:0008284]; small GTPase mediated signal transduction [GO:0007264] comp137281_c0_seq7,1406,36.6287,0.47347674,15,12,,2.00E-92,P79800,GTPase KRas (K-Ras 2) (Ki-Ras) (K-ras),GTPase KRas (K-Ras 2) (Ki-Ras) (K-ras),GO:0005525; GO:0003924; GO:0005886; GO:0007264,GTP binding; GTPase activity; plasma membrane; small GTPase mediated signal transduction,PF00071;,2.00E-134,CHOYP_RAS.1.1,,,,,,,RASK_MELGA,Meleagris gallopavo (Common turkey),positive regulation of cell proliferation [GO:0008284]; small GTPase mediated signal transduction [GO:0007264] comp137286_c1_seq1,1071,40.8964,0.45246425,0,9,,2.00E-86,P37895,Putative GTPase CC_2483 (EC 3.6.-.-),Putative GTPase CC_2483 (EC 3.6.-.-),GO:0005524; GO:0005525; GO:0017111,ATP binding; GTP binding; nucleoside-triphosphatase activity,,2.00E-100,CHOYP_MMAA.1.1,,,,,,,Y2483_CAUCR,Caulobacter crescentus (strain ATCC 19089 / CB15), comp137286_c1_seq2,1142,40.8056,0.49240518,8,39,,2.00E-139,Q8C7H1,"Methylmalonic aciduria type A homolog, mitochondrial (EC 3.6.-.-)","Methylmalonic aciduria type A homolog, mitochondrial (EC 3.6.-.-)",GO:0005525; GO:0009236; GO:0005739; GO:0017111,GTP binding; cobalamin biosynthetic process; mitochondrion; nucleoside-triphosphatase activity,,,,,,,,,,MMAA_MOUSE,Mus musculus (Mouse),cobalamin biosynthetic process [GO:0009236] comp137287_c0_seq1,1097,43.938,0.90656202,16,1602,female>male,5.00E-69,Q5XK91,Fibrinogen C domain-containing protein 1-B,Fibrinogen C domain-containing protein 1-B,GO:0008061; GO:0016021; GO:0046872,chitin binding; integral to membrane; metal ion binding,PF00147;,,,,,,,,,FBCDB_XENLA,Xenopus laevis (African clawed frog), comp137290_c0_seq1,519,45.6647,0.56391187,22,69,,4.00E-09,P18713,Gastrula zinc finger protein XlCGF17.1 (Fragment),Gastrula zinc finger protein XlCGF17.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG17_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137290_c0_seq2,476,44.7479,0.38221323,6,49,,2.00E-12,P08042,Zinc finger protein 1 (Zfp-1) (Protein mKR1),Zinc finger protein 1 (Zfp-1) (Protein mKR1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13465;,,,,,,,,,ZFP1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137290_c0_seq3,812,38.3005,0.53921488,0,5,,1.00E-07,O93567,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),GO:0003677; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_CHICK,Gallus gallus (Chicken),"transcription, DNA-templated [GO:0006351]" comp137290_c0_seq4,943,40.8271,0.51424583,4,96,,8.00E-08,O95365,Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A),Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A),GO:0003677; GO:0030154; GO:0035035; GO:0046872; GO:0007275; GO:0000122; GO:0045892; GO:0005634; GO:0006351,"DNA binding; cell differentiation; histone acetyltransferase binding; metal ion binding; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; transcription, DNA-templated [GO:0006351]" comp137290_c2_seq1,212,51.4151,1.01086995,0,23,,1.00E-13,Q3US17,Zinc finger protein 48 (Zinc finger protein 553),Zinc finger protein 48 (Zinc finger protein 553),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZNF48_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137292_c0_seq1,1917,35.4721,0.43978811,21,57,,6.00E-129,Q9QZ73,DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Testis-specific protein 3),DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Testis-specific protein 3),GO:0000151,ubiquitin ligase complex,PF03556;,2.00E-141,CHOYP_ISCW_ISCW023153.1.1,,,,,,,DCNL1_MOUSE,Mus musculus (Mouse),positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] comp137292_c0_seq2,1935,35.3488,0.47317209,18,84,,7.00E-129,Q9QZ73,DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Testis-specific protein 3),DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Testis-specific protein 3),GO:0000151,ubiquitin ligase complex,PF03556;,,,,,1.00E-107,AM861293.p.cg.6,7,,DCNL1_MOUSE,Mus musculus (Mouse),positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] comp137299_c0_seq1,354,46.0452,0.49260338,0,0,,2.00E-42,O60907,"F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked)","F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked)",GO:0007219; GO:0060070; GO:0044255; GO:0042393; GO:0000122; GO:0045944; GO:0043161; GO:0007605; GO:0044281; GO:0005876; GO:0003714; GO:0044212; GO:0006351; GO:0017053,"Notch signaling pathway; canonical Wnt receptor signaling pathway; cellular lipid metabolic process; histone binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; sensory perception of sound; small molecule metabolic process; spindle microtubule; transcription corepressor activity; transcription regulatory region DNA binding; transcription, DNA-dependent; transcriptional repressor complex",PF08513;PF00400;,,,,,,,,,TBL1X_HUMAN,Homo sapiens (Human),"canonical Wnt signaling pathway [GO:0060070]; cellular lipid metabolic process [GO:0044255]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]" comp137299_c0_seq2,2561,41.8586,0.64603627,3,0,,0,Q9QXE7,F-box-like/WD repeat-containing protein TBL1X (Transducin beta-like protein 1X),F-box-like/WD repeat-containing protein TBL1X (Transducin beta-like protein 1X),GO:0003682; GO:0045444; GO:0045892; GO:0005654; GO:0045944; GO:0043161; GO:0043627; GO:0003714; GO:0005667; GO:0044212; GO:0006351,"chromatin binding; fat cell differentiation; negative regulation of transcription, DNA-dependent; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; response to estrogen stimulus; transcription corepressor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent",PF08513;PF00400;,,,,,,,,,TBL1X_MOUSE,Mus musculus (Mouse),"canonical Wnt signaling pathway [GO:0060070]; fat cell differentiation [GO:0045444]; histone deacetylation [GO:0016575]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis [GO:0006508]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estrogen [GO:0043627]; response to steroid hormone [GO:0048545]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]" comp137299_c0_seq4,1530,40.5882,0.63700125,0,0,,7.00E-31,Q9D7H2,WD repeat-containing protein 5B,WD repeat-containing protein 5B,,,PF00400;,,,,,,,,,WDR5B_MOUSE,Mus musculus (Mouse), comp137299_c0_seq5,1869,42.1081,0.63130577,0,0,,0,Q95RJ9,F-box-like/WD repeat-containing protein ebi,F-box-like/WD repeat-containing protein ebi,GO:0005525; GO:0007219; GO:0007049; GO:0022416; GO:0003682; GO:0042676; GO:0007173; GO:0000122; GO:0042461; GO:0005700; GO:0045747; GO:0031065; GO:0045572; GO:0042058; GO:0030162; GO:0017053; GO:0007601; GO:0035220,GTP binding; Notch signaling pathway; cell cycle; chaeta development; chromatin binding; compound eye cone cell fate commitment; epidermal growth factor receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; photoreceptor cell development; polytene chromosome; positive regulation of Notch signaling pathway; positive regulation of histone deacetylation; positive regulation of imaginal disc growth; regulation of epidermal growth factor receptor signaling pathway; regulation of proteolysis; transcriptional repressor complex; visual perception; wing disc development,PF08513;PF00400;,0,CHOYP_AAEL_AAEL003539.1.1,,,,,,,EBI_DROME,Drosophila melanogaster (Fruit fly),"cell cycle [GO:0007049]; cellular response to light stimulus [GO:0071482]; chaeta development [GO:0022416]; compound eye cone cell fate commitment [GO:0042676]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron cellular homeostasis [GO:0070050]; Notch signaling pathway [GO:0007219]; photoreceptor cell development [GO:0042461]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of imaginal disc growth [GO:0045572]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteolysis [GO:0030162]; response to oxidative stress [GO:0006979]; visual perception [GO:0007601]; wing disc development [GO:0035220]" comp137299_c0_seq6,1045,42.8708,0.61280864,0,0,,,,,,,,,5.00E-90,CHOYP_AAEL_AAEL003539.1.1,,,,,,,,, comp137300_c0_seq1,2394,42.523,1.1238639,613,0,male,1.00E-18,Q95JR6,Cyclic nucleotide-binding domain-containing protein 2,Cyclic nucleotide-binding domain-containing protein 2,,,PF00027;,,,,,,,,,CT152_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp137300_c0_seq2,1373,39.9854,1.16874065,0,0,,2.00E-15,Q96M20,Cyclic nucleotide-binding domain-containing protein 2,Cyclic nucleotide-binding domain-containing protein 2,,,PF00027;,,,,,,,,,CT152_HUMAN,Homo sapiens (Human),spermatogenesis [GO:0007283] comp137303_c0_seq1,1958,38.9173,0.71081296,105,368,,,,,,,,,,,3.00E-43,ruditapes_c17388,,,,,,, comp137303_c0_seq2,1711,40.7364,0.69714974,79,181,,3.00E-48,P82925,"28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt)","28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt)",GO:0005763; GO:0003735,mitochondrial small ribosomal subunit; structural constituent of ribosome,PF15433;,,,,,,,,,RT31_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp137307_c0_seq1,1793,34.4116,0.53659804,4,31,,4.00E-07,A3E4D8,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALM_PROMN,Prorocentrum minimum (Dinoflagellate) (Exuviaella minima), comp137307_c0_seq2,1684,34.8575,0.57568174,0,12,,9.00E-125,P42325,Neurocalcin homolog (DrosNCa),Neurocalcin homolog (DrosNCa),GO:0005509,calcium ion binding,PF00036;PF13499;,6.00E-123,CHOYP_NECX.1.1,,,,,,,NCAH_DROME,Drosophila melanogaster (Fruit fly),negative regulation of phosphorylation [GO:0042326] comp137310_c0_seq1,1387,33.8861,0.30626671,122,346,,,,,,,,,4.00E-29,CHOYP_ISCW_ISCW020693.1.1,,,,,,,,, comp137310_c0_seq3,1332,33.4835,0.30105756,12,147,,2.00E-29,Q9CPT5,Nucleolar protein 16,Nucleolar protein 16,GO:0005730,nucleolus,PF09420;,4.00E-29,CHOYP_ISCW_ISCW020693.1.1,,,,,,,NOP16_MOUSE,Mus musculus (Mouse),ribosomal large subunit biogenesis [GO:0042273] comp137311_c1_seq1,3377,40.2724,0.42459354,68,221,,4.00E-112,Q08705,Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog),Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,CTCF_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137311_c1_seq2,2137,44.6888,0.45035424,4,10,,4.00E-59,Q9UJW8,Zinc finger protein 180 (HHZ168),Zinc finger protein 180 (HHZ168),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,6.00E-118,CHOYP_LOC100905908.1.1,,,,,,,ZN180_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137313_c1_seq1,2224,42.0863,0.8804058,194,192,,1.00E-98,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,1.00E-18,CHOYP_BRAFLDRAFT_208293.20.20,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp137314_c0_seq2,1851,40.6807,0.48906603,62,147,,1.00E-124,P50747,Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)],Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)],GO:0005524; GO:0009374; GO:0006768; GO:0004077; GO:0004078; GO:0004079; GO:0004080; GO:0008283; GO:0000785; GO:0005829; GO:0071110; GO:0005739; GO:0005652; GO:0016363; GO:0070781,ATP binding; biotin binding; biotin metabolic process; biotin-[acetyl-CoA-carboxylase] ligase activity; biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity; biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity; biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity; cell proliferation; chromatin; cytosol; histone biotinylation; mitochondrion; nuclear lamina; nuclear matrix; response to biotin,PF02237;PF03099;PF09825;,1.00E-55,CHOYP_CP2CN.1.1,,,,,,,BPL1_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; cell proliferation [GO:0008283]; histone biotinylation [GO:0071110]; histone modification [GO:0016570]; protein biotinylation [GO:0009305]; response to biotin [GO:0070781] comp137315_c1_seq1,787,46.3787,0.51112017,33,135,,2.00E-49,Q9DE13,Bromodomain adjacent to zinc finger domain protein 2B (Extracellular matrix protein F22),Bromodomain adjacent to zinc finger domain protein 2B (Extracellular matrix protein F22),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF01429;PF00628;PF15613;,,,,,,,,,BAZ2B_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137315_c2_seq2,1078,46.7532,0.83547742,3,7,,3.00E-47,Q9UIF8,Bromodomain adjacent to zinc finger domain protein 2B (hWALp4),Bromodomain adjacent to zinc finger domain protein 2B (hWALp4),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF01429;PF00628;PF15613;,5.00E-14,CHOYP_BRAFLDRAFT_122791.6.6,,,,,,,BAZ2B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137317_c3_seq1,886,42.4379,0.50656832,66,11,,1.00E-22,Q54KF6,Protein DDB_G0287365,Protein DDB_G0287365,,,PF10162;,8.00E-49,CHOYP_BRAFLDRAFT_119774.4.4,,,,,,,Y7365_DICDI,Dictyostelium discoideum (Slime mold), comp137317_c3_seq2,2097,40.9633,0.47993475,162,6,,2.00E-142,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,8.00E-15,CHOYP_BRAFLDRAFT_119774.2.4,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp137320_c0_seq1,4330,41.1085,0.45596473,34,283,,,,,,,,,1.00E-99,CHOYP_IF4G2.1.1,,,,,,,,, comp137320_c0_seq2,4287,41.4042,0.45957514,37,223,,1.00E-108,P79398,Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Novel APOBEC-1 target 1) (Translation repressor NAT1) (p97),Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Novel APOBEC-1 target 1) (Translation repressor NAT1) (p97),GO:0016281; GO:0006446; GO:0003743,eukaryotic translation initiation factor 4F complex; regulation of translational initiation; translation initiation factor activity,PF02847;PF02854;PF02020;,,,,,,,,,IF4G2_RABIT,Oryctolagus cuniculus (Rabbit),regulation of translational initiation [GO:0006446] comp137321_c0_seq1,2938,44.452,0.51598611,10,0,,3.00E-45,Q8IVV2,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,5.00E-64,CHOYP_LOC100175334.1.2,,,,,,,LOXH1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp137321_c0_seq2,2908,44.4635,0.52224934,15,0,,2.00E-23,Q8CGM2,Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1),Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1),GO:0030030; GO:0035085; GO:0005856; GO:0035556; GO:0042461; GO:0045494; GO:0032391; GO:0001750; GO:0007601,cell projection organization; cilium axoneme; cytoskeleton; intracellular signal transduction; photoreceptor cell development; photoreceptor cell maintenance; photoreceptor connecting cilium; photoreceptor outer segment; visual perception,PF03607;,2.00E-62,CHOYP_LOC100175334.1.2,,,,,,,RP1L1_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; intracellular signal transduction [GO:0035556]; photoreceptor cell development [GO:0042461]; photoreceptor cell maintenance [GO:0045494]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601] comp137324_c0_seq1,1885,39.2573,0.37705766,77,425,,0,P21265,Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase),Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase),GO:0044208; GO:0006189; GO:0070626; GO:0006167; GO:0004018; GO:0005829; GO:0006144,"'de novo' AMP biosynthetic process; 'de novo' IMP biosynthetic process; (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; AMP biosynthetic process; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; cytosol; purine nucleobase metabolic process",PF10397;PF00206;,0,CHOYP_PUR8.1.1,,,,,,,PUR8_CHICK,Gallus gallus (Chicken),'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; protein tetramerization [GO:0051262]; purine nucleotide metabolic process [GO:0006163] comp137325_c0_seq1,943,34.4645,0.60903294,2634,5454,,1.00E-07,Q9CQX8,"28S ribosomal protein S36, mitochondrial (MRP-S36) (S36mt)","28S ribosomal protein S36, mitochondrial (MRP-S36) (S36mt)",GO:0005763,mitochondrial small ribosomal subunit,PF10937;,,,,,,,,,RT36_MOUSE,Mus musculus (Mouse),2-oxoglutarate metabolic process [GO:0006103]; oxidation-reduction process [GO:0055114] comp137326_c0_seq2,931,36.7347,0.38952399,3,44,,5.00E-12,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,5.00E-26,CHOYP_LOC100207270.3.3,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp137326_c0_seq3,431,37.587,0.27033938,5,25,,,,,,,,,8.00E-26,CHOYP_LOC100207270.3.3,,,,,,,,, comp137328_c1_seq2,2003,38.692,1.21936964,4,491,female>male,2.00E-111,Q9VUL9,"Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)","Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)",GO:0033932; GO:0032580; GO:0005797; GO:0036071; GO:0018392; GO:0016021; GO:0007399; GO:0006486,"1,3-alpha-L-fucosidase activity; Golgi cisterna membrane; Golgi medial cisterna; N-glycan fucosylation; glycoprotein 3-alpha-L-fucosyltransferase activity; integral to membrane; nervous system development; protein glycosylation",PF17039;PF00852;,7.00E-73,CHOYP_DWIL_GK20401.1.1,,,,,,,FUCTA_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] comp137332_c0_seq1,1626,45.203,0.51919129,157,151,,3.00E-129,Q15262,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0005912; GO:0030424; GO:0016477; GO:0009986; GO:0005911; GO:0034644; GO:0034614; GO:0030425; GO:0048041; GO:0005887; GO:0031256; GO:0045786; GO:0030336; GO:0010839; GO:0045892; GO:0043025; GO:0001750; GO:0034394; GO:0007179; GO:0005001,"adherens junction; axon; cell migration; cell surface; cell-cell junction; cellular response to UV; cellular response to reactive oxygen species; dendrite; focal adhesion assembly; integral to plasma membrane; leading edge membrane; negative regulation of cell cycle; negative regulation of cell migration; negative regulation of keratinocyte proliferation; negative regulation of transcription, DNA-dependent; neuronal cell body; photoreceptor outer segment; protein localization to cell surface; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein tyrosine phosphatase activity",PF00041;PF07679;PF00629;PF00102;,1.00E-125,CHOYP_PTPRK.17.20,1.00E-92,ruditapes_c16833,,,,,PTPRK_HUMAN,Homo sapiens (Human),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp137332_c1_seq1,1789,45.5003,0.59455413,223,257,,2.00E-30,A0JM12,Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10),Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10),GO:0007155; GO:0016021; GO:0006909; GO:0005886; GO:0014719; GO:0014816; GO:0014841,cell adhesion; integral to membrane; phagocytosis; plasma membrane; satellite cell activation; satellite cell differentiation; satellite cell proliferation,PF12661;PF00053;,5.00E-17,CHOYP_PTPRK.17.20,,,,,,,MEG10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell proliferation [GO:0014841] comp137333_c1_seq2,1205,39.3361,0.58009771,0,0,,8.00E-86,Q9P0U3,Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1),Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1),GO:0016929; GO:0006919; GO:0097190; GO:0005737; GO:0004175; GO:0032435; GO:0005654; GO:0045944; GO:0016926; GO:0016925; GO:0006508; GO:0010724,SUMO-specific protease activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; cytoplasm; endopeptidase activity; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein desumoylation; protein sumoylation; proteolysis; regulation of definitive erythrocyte differentiation,PF02902;,,,,,,,,,SENP1_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724] comp137333_c1_seq6,1175,39.1489,0.59893092,0,0,,6.00E-86,Q9P0U3,Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1),Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1),GO:0016929; GO:0006919; GO:0097190; GO:0005737; GO:0004175; GO:0032435; GO:0005654; GO:0045944; GO:0016926; GO:0016925; GO:0006508; GO:0010724,SUMO-specific protease activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; cytoplasm; endopeptidase activity; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; protein desumoylation; protein sumoylation; proteolysis; regulation of definitive erythrocyte differentiation,PF02902;,,,,,,,,,SENP1_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724] comp137333_c1_seq8,1519,39.8947,0.68002893,0,0,,,,,,,,,4.00E-62,CHOYP_LOC592825.1.1,,,,,,,,, comp137338_c0_seq1,3533,43.589,0.52366796,4,17,,0,A2AWA9,Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA),Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA),GO:0005097; GO:0007049; GO:0005829; GO:0005815; GO:0032851,Rab GTPase activator activity; cell cycle; cytosol; microtubule organizing center; positive regulation of Rab GTPase activity,PF12473;PF00640;PF00566;,,,,,,,,,RBGP1_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp137338_c0_seq2,3518,43.718,0.52268091,0,0,,0,A2AWA9,Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA),Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA),GO:0005097; GO:0007049; GO:0005829; GO:0005815; GO:0032851,Rab GTPase activator activity; cell cycle; cytosol; microtubule organizing center; positive regulation of Rab GTPase activity,PF12473;PF00640;PF00566;,,,,,,,,,RBGP1_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp137338_c0_seq3,2267,45.4786,0.47232118,0,0,,8.00E-10,Q69ZT9,TBC1 domain family member 30,TBC1 domain family member 30,GO:0005097; GO:0005886; GO:0032851,Rab GTPase activator activity; plasma membrane; positive regulation of Rab GTPase activity,PF15733;PF00566;,,,,,,,,,TBC30_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; negative regulation of cilium assembly [GO:1902018]; regulation of cilium assembly [GO:1902017]; regulation of vesicle fusion [GO:0031338] comp137338_c0_seq4,2261,42.5033,0.4860933,0,0,,5.00E-83,Q9VYY9,Ecotropic viral integration site 5 ortholog,Ecotropic viral integration site 5 ortholog,GO:0005097; GO:0007298; GO:0005737; GO:0005768; GO:0030334; GO:0032880; GO:0031982,Rab GTPase activator activity; border follicle cell migration; cytoplasm; endosome; regulation of cell migration; regulation of protein localization; vesicle,PF00566;,0,CHOYP_RABGAP1.1.1,,,,,,,Y1727_DROME,Drosophila melanogaster (Fruit fly),activation of GTPase activity [GO:0090630]; border follicle cell migration [GO:0007298]; intracellular protein transport [GO:0006886]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338] comp137338_c0_seq6,2276,42.3989,0.4953533,0,0,,2.00E-78,O60447,Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein),Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein),GO:0005097; GO:0007049; GO:0051301; GO:0008283; GO:0005737; GO:0005815; GO:0007275; GO:0005634; GO:0032851; GO:0005819,Rab GTPase activator activity; cell cycle; cell division; cell proliferation; cytoplasm; microtubule organizing center; multicellular organismal development; nucleus; positive regulation of Rab GTPase activity; spindle,PF00566;,0,CHOYP_RABGAP1.1.1,,,,,,,EVI5_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; intracellular protein transport [GO:0006886]; multicellular organism development [GO:0007275]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]" comp137338_c0_seq7,1010,44.9505,0.33589386,0,0,,4.00E-123,Q9Y3P9,Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA),Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA),GO:0003677; GO:0005096; GO:0005097; GO:0007049; GO:0005813; GO:0005829; GO:0005875; GO:0032851; GO:0015631,DNA binding; GTPase activator activity; Rab GTPase activator activity; cell cycle; centrosome; cytosol; microtubule associated complex; positive regulation of Rab GTPase activity; tubulin binding,PF12473;PF00640;PF00566;,,,,,,,,,RBGP1_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp137341_c1_seq1,1212,35.396,0.48791095,212,979,,1.00E-13,Q9FPJ8,Polyadenylate-binding protein RBP45A (Poly(A)-binding protein RBP45A) (RNA-binding protein 45A) (AtRBP45A),Polyadenylate-binding protein RBP45A (Poly(A)-binding protein RBP45A) (RNA-binding protein 45A) (AtRBP45A),GO:0005829; GO:0006397; GO:0000166; GO:0005634; GO:0008143,cytosol; mRNA processing; nucleotide binding; nucleus; poly(A) RNA binding,PF00076;,8.00E-63,CHOYP_LOC101168891.1.1,,,,,,,RB45A_ARATH,Arabidopsis thaliana (Mouse-ear cress),mRNA processing [GO:0006397] comp137341_c1_seq2,1235,35.3036,0.50800414,44,209,,9.00E-60,A2VDB3,RNA-binding protein 42 (RNA-binding motif protein 42),RNA-binding protein 42 (RNA-binding motif protein 42),GO:0003723; GO:0005737; GO:0000166; GO:0005634,RNA binding; cytoplasm; nucleotide binding; nucleus,PF00076;,,,3.00E-53,ruditapes2_c3032,,,,,RBM42_XENLA,Xenopus laevis (African clawed frog), comp137342_c0_seq1,750,38.6667,0.68416884,113,336,,8.00E-62,Q9NXW9,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 4),Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 4),GO:0003779; GO:0031032; GO:0036090; GO:0070938; GO:0032451; GO:0046872; GO:0030496; GO:0005739; GO:0005634; GO:0016706; GO:0006482; GO:0006355; GO:0006351,"actin binding; actomyosin structure organization; cleavage furrow ingression; contractile ring; demethylase activity; metal ion binding; midbody; mitochondrion; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; protein demethylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,1.00E-33,CHOYP_LOC100367945.1.1,,,,,,,ALKB4_HUMAN,Homo sapiens (Human),"actomyosin structure organization [GO:0031032]; cleavage furrow ingression [GO:0036090]; protein demethylation [GO:0006482]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137345_c0_seq5,204,45.5882,0,11,0,,,,,,,,,,,3.00E-18,ruditapes2_c744,,,,,,, comp137346_c0_seq1,1515,49.505,0.39935656,48,53,,3.00E-10,Q7TN29,Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like),Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like),GO:0008060; GO:0005737; GO:0005634; GO:0043547; GO:0032312; GO:0008270,ARF GTPase activator activity; cytoplasm; nucleus; positive regulation of GTPase activity; regulation of ARF GTPase activity; zinc ion binding,PF01412;,,,,,,,,,SMAP2_MOUSE,Mus musculus (Mouse), comp137346_c0_seq2,1476,49.6612,0.38530644,31,39,,4.00E-71,Q4KLH5,Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein homolog) (Nucleoporin-like protein RIP),Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein homolog) (Nucleoporin-like protein RIP),GO:0008060; GO:0003677; GO:0030154; GO:0016023; GO:0007275; GO:0005634; GO:0032312; GO:0007283; GO:0006810; GO:0008270,ARF GTPase activator activity; DNA binding; cell differentiation; cytoplasmic membrane-bounded vesicle; multicellular organismal development; nucleus; regulation of ARF GTPase activity; spermatogenesis; transport; zinc ion binding,PF01412;,3.00E-75,CHOYP_LOC100371923.1.1,,,,,,,AGFG1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; transport [GO:0006810] comp137347_c0_seq11,3331,43.3503,0.74308804,0,0,,0,P23188,Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3),Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3),GO:0008283; GO:0009986; GO:0005769; GO:0005788; GO:0005615; GO:0016021; GO:0045121; GO:0046872; GO:0032804; GO:0032911; GO:0032902; GO:0042277; GO:0043043; GO:0016486; GO:0005886; GO:0016485; GO:0006508; GO:0009966; GO:0032940; GO:0004252; GO:0004867; GO:0006465; GO:0005802; GO:0012510,cell proliferation; cell surface; early endosome; endoplasmic reticulum lumen; extracellular space; integral to membrane; membrane raft; metal ion binding; negative regulation of low-density lipoprotein particle receptor catabolic process; negative regulation of transforming growth factor beta1 production; nerve growth factor production; peptide binding; peptide biosynthetic process; peptide hormone processing; plasma membrane; protein processing; proteolysis; regulation of signal transduction; secretion by cell; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity; signal peptide processing; trans-Golgi network; trans-Golgi network transport vesicle membrane,PF01483;PF00082;PF16470;,3.00E-168,CHOYP_FURI1.2.2,,,,,,,FURIN_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cell proliferation [GO:0008283]; collagen catabolic process [GO:0030574]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058] comp137347_c0_seq13,3383,43.3048,0.73308022,0,0,,0,P30430,"Furin-like protease 1, isoform 1-CRR (Furin-1) (EC 3.4.21.75) (Kex2-like endoprotease 1) (dKLIP-1)","Furin-like protease 1, isoform 1-CRR (Furin-1) (EC 3.4.21.75) (Kex2-like endoprotease 1) (dKLIP-1)",GO:0000139; GO:0016021; GO:0005886; GO:0006508; GO:0004252; GO:0008039,Golgi membrane; integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity; synaptic target recognition,PF01483;PF00082;PF16470;,,,,,,,,,FUR1C_DROME,Drosophila melanogaster (Fruit fly),glutamate receptor clustering [GO:0097688]; postsynaptic membrane organization [GO:0001941]; presynaptic membrane organization [GO:0097090]; proteolysis [GO:0006508]; synaptic target recognition [GO:0008039] comp137347_c0_seq14,2373,44.4164,0.66324169,0,0,,0,P23188,Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3),Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3),GO:0008283; GO:0009986; GO:0005769; GO:0005788; GO:0005615; GO:0016021; GO:0045121; GO:0046872; GO:0032804; GO:0032911; GO:0032902; GO:0042277; GO:0043043; GO:0016486; GO:0005886; GO:0016485; GO:0006508; GO:0009966; GO:0032940; GO:0004252; GO:0004867; GO:0006465; GO:0005802; GO:0012510,cell proliferation; cell surface; early endosome; endoplasmic reticulum lumen; extracellular space; integral to membrane; membrane raft; metal ion binding; negative regulation of low-density lipoprotein particle receptor catabolic process; negative regulation of transforming growth factor beta1 production; nerve growth factor production; peptide binding; peptide biosynthetic process; peptide hormone processing; plasma membrane; protein processing; proteolysis; regulation of signal transduction; secretion by cell; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity; signal peptide processing; trans-Golgi network; trans-Golgi network transport vesicle membrane,PF01483;PF00082;PF16470;,1.00E-164,CHOYP_FURI1.1.2,,,,,,,FURIN_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cell proliferation [GO:0008283]; collagen catabolic process [GO:0030574]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058] comp137347_c0_seq2,3028,44.1876,0.69272388,0,0,,0,P29122,Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4),Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4),GO:0005796; GO:0009986; GO:0007368; GO:0012505; GO:0005783; GO:0031012; GO:0005615; GO:0009100; GO:0008201; GO:0016020; GO:0048406; GO:0032455; GO:0032902; GO:0048011; GO:0006508; GO:0030510; GO:0032940; GO:0004252; GO:0007354,"Golgi lumen; cell surface; determination of left/right symmetry; endomembrane system; endoplasmic reticulum; extracellular matrix; extracellular space; glycoprotein metabolic process; heparin binding; membrane; nerve growth factor binding; nerve growth factor processing; nerve growth factor production; neurotrophin TRK receptor signaling pathway; proteolysis; regulation of BMP signaling pathway; secretion by cell; serine-type endopeptidase activity; zygotic determination of anterior/posterior axis, embryo",PF14843;PF01483;PF00082;PF08686;PF16470;,2.00E-163,CHOYP_FUR.1.1,,,,,,,PCSK6_HUMAN,Homo sapiens (Human),"determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; regulation of BMP signaling pathway [GO:0030510]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]" comp137347_c0_seq3,2976,44.254,0.70289416,0,0,,0,P23188,Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3),Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3),GO:0008283; GO:0009986; GO:0005769; GO:0005788; GO:0005615; GO:0016021; GO:0045121; GO:0046872; GO:0032804; GO:0032911; GO:0032902; GO:0042277; GO:0043043; GO:0016486; GO:0005886; GO:0016485; GO:0006508; GO:0009966; GO:0032940; GO:0004252; GO:0004867; GO:0006465; GO:0005802; GO:0012510,cell proliferation; cell surface; early endosome; endoplasmic reticulum lumen; extracellular space; integral to membrane; membrane raft; metal ion binding; negative regulation of low-density lipoprotein particle receptor catabolic process; negative regulation of transforming growth factor beta1 production; nerve growth factor production; peptide binding; peptide biosynthetic process; peptide hormone processing; plasma membrane; protein processing; proteolysis; regulation of signal transduction; secretion by cell; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity; signal peptide processing; trans-Golgi network; trans-Golgi network transport vesicle membrane,PF01483;PF00082;PF16470;,3.00E-168,CHOYP_FURI1.2.2,,,,,,,FURIN_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cell proliferation [GO:0008283]; collagen catabolic process [GO:0030574]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058] comp137347_c0_seq4,2018,45.9366,0.59836026,0,0,,4.00E-158,P30432,Furin-like protease 2 (Furin-2) (EC 3.4.21.75),Furin-like protease 2 (Furin-2) (EC 3.4.21.75),GO:0016021; GO:0005886; GO:0006508; GO:0004252,integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity,PF14843;PF01483;PF00082;PF16470;,,,,,,,,,FUR2_DROME,Drosophila melanogaster (Fruit fly),negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906] comp137347_c0_seq6,2113,45.3857,0.69338772,0,0,,0,P30430,"Furin-like protease 1, isoform 1-CRR (Furin-1) (EC 3.4.21.75) (Kex2-like endoprotease 1) (dKLIP-1)","Furin-like protease 1, isoform 1-CRR (Furin-1) (EC 3.4.21.75) (Kex2-like endoprotease 1) (dKLIP-1)",GO:0000139; GO:0016021; GO:0005886; GO:0006508; GO:0004252; GO:0008039,Golgi membrane; integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity; synaptic target recognition,PF01483;PF00082;PF16470;,1.00E-164,CHOYP_FURI1.1.2,,,,,,,FUR1C_DROME,Drosophila melanogaster (Fruit fly),glutamate receptor clustering [GO:0097688]; postsynaptic membrane organization [GO:0001941]; presynaptic membrane organization [GO:0097090]; proteolysis [GO:0006508]; synaptic target recognition [GO:0008039] comp137347_c0_seq7,1758,47.3265,0.6249689,0,0,,1.00E-104,Q16549,Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),GO:0030173; GO:0016486; GO:0006508; GO:0004252,integral to Golgi membrane; peptide hormone processing; proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,2.00E-168,CHOYP_FURI1.2.2,,,,,,,PCSK7_HUMAN,Homo sapiens (Human),peptide hormone processing [GO:0016486]; protein processing [GO:0016485] comp137348_c0_seq2,2512,46.0191,0.43709728,0,3,,,,,,,,,0,CHOYP_BRAFLDRAFT_126355.1.2,,,,,,,,, comp137348_c0_seq3,2674,46.3351,0.43939361,0,0,,,,,,,,,2.00E-75,CHOYP_BRAFLDRAFT_126355.2.2,,,,,,,,, comp137348_c0_seq4,2924,45.3146,0.42005175,5,0,,,,,,,,,0,CHOYP_BRAFLDRAFT_126355.1.2,,,,,,,,, comp137349_c0_seq1,2290,43.7118,0.53966154,902,2604,,1.00E-22,Q5U317,Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein),Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein),GO:0003723; GO:0005847; GO:0006397,RNA binding; mRNA cleavage and polyadenylation specificity factor complex; mRNA processing,PF05182;,7.00E-23,CHOYP_LOC100370896.4.4,,,,,,,FIP1_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397] comp137351_c0_seq1,2737,38.2901,0.46041709,58,202,,4.00E-32,Q9H074,Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1),Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1),GO:0003723; GO:0005829; GO:0048255; GO:0000289; GO:0008494; GO:0006413,RNA binding; cytosol; mRNA stabilization; nuclear-transcribed mRNA poly(A) tail shortening; translation activator activity; translational initiation,PF02854;PF07145;,,,,,,,,,PAIP1_HUMAN,Homo sapiens (Human),mRNA stabilization [GO:0048255]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; translational initiation [GO:0006413] comp137354_c0_seq3,1700,46.2941,0.51217518,5,0,,0,Q9QXG4,"Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)","Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)",GO:0005524; GO:0003987; GO:0006085; GO:0005737,ATP binding; acetate-CoA ligase activity; acetyl-CoA biosynthetic process; cytoplasm,PF16177;PF00501;PF13193;,2.00E-173,CHOYP_ACSA.1.1,,,,,,,ACSA_MOUSE,Mus musculus (Mouse),acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; lipid biosynthetic process [GO:0008610]; propionate biosynthetic process [GO:0019542] comp137358_c0_seq10,1249,51.5612,0.86308992,17,96,,,,,,,,,6.00E-14,CHOYP_RN45S.2.5,,,,,,,,, comp137358_c0_seq25,1460,52.3973,0.91735546,0,0,,,,,,,,,7.00E-14,CHOYP_RN45S.2.5,,,,,,,,, comp137366_c1_seq1,3215,42.8616,0.28562233,0,8,,4.00E-176,P19096,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0004313; GO:0004314; GO:0071353; GO:0047117; GO:0004319; GO:0006633; GO:0042587; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0005886; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; cellular response to interleukin-4; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; glycogen granule; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; plasma membrane; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,3.00E-35,CHOYP_FASN.3.4,,,,,,,FAS_MOUSE,Mus musculus (Mouse),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649] comp137366_c1_seq2,4596,41.7755,0.27661458,2,45,,1.00E-25,A1KQG0,Phthioceranic/hydroxyphthioceranic acid synthase (EC 2.3.1.-) (Polyketide synthase pks2),Phthioceranic/hydroxyphthioceranic acid synthase (EC 2.3.1.-) (Polyketide synthase pks2),GO:0006633; GO:0016491; GO:0016747; GO:0008270,"fatty acid biosynthetic process; oxidoreductase activity; transferase activity, transferring acyl groups other than amino-acyl groups; zinc ion binding",PF00698;PF08240;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;,,,,,,,,,PHAS_MYCBP,Mycobacterium bovis (strain BCG / Pasteur 1173P2),fatty acid biosynthetic process [GO:0006633] comp137366_c1_seq3,4417,42.0421,0.25739297,7,78,,0,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,4.00E-35,CHOYP_FASN.3.4,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp137366_c2_seq1,1099,45.0409,0.38147801,13,145,,2.00E-84,P36189,Fatty acid synthase (EC 2.3.1.85) (Fragment),Fatty acid synthase (EC 2.3.1.85) (Fragment),GO:0006633; GO:0004312; GO:0016787; GO:0016874; GO:0016491,fatty acid biosynthetic process; fatty acid synthase activity; hydrolase activity; ligase activity; oxidoreductase activity,PF00109;PF02801;,,,,,,,,,FAS_ANSAN,Anser anser anser (Western greylag goose),fatty acid biosynthetic process [GO:0006633] comp137366_c3_seq1,879,47.554,0.3653394,0,0,,,,,,,,,6.00E-31,CHOYP_FASN.1.4,,,,,,,,, comp137366_c3_seq2,1971,46.7783,0.36374825,10,228,,0,P19096,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0004313; GO:0004314; GO:0071353; GO:0047117; GO:0004319; GO:0006633; GO:0042587; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0005886; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; cellular response to interleukin-4; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; glycogen granule; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; plasma membrane; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,4.00E-44,CHOYP_LOC100374692.1.1,,,,,,,FAS_MOUSE,Mus musculus (Mouse),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649] comp137370_c1_seq1,2083,41.4786,0.39213048,8,133,,5.00E-48,Q8BJW7,Crossover junction endonuclease EME1 (EC 3.1.22.-),Crossover junction endonuclease EME1 (EC 3.1.22.-),GO:0003677; GO:0006310; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005730,DNA binding; DNA recombination; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleolus,PF02732;,,,2.00E-45,ruditapes_c17622,,,,,EME1_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; response to intra-S DNA damage checkpoint signaling [GO:0072429] comp137370_c1_seq2,2168,41.0517,0.4078261,18,93,,5.00E-48,Q8BJW7,Crossover junction endonuclease EME1 (EC 3.1.22.-),Crossover junction endonuclease EME1 (EC 3.1.22.-),GO:0003677; GO:0006310; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005730,DNA binding; DNA recombination; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleolus,PF02732;,2.00E-30,CHOYP_LOC100889179.2.2,,,,,,,EME1_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; response to intra-S DNA damage checkpoint signaling [GO:0072429] comp137370_c1_seq3,468,41.2393,0.61643217,0,9,,3.00E-06,Q7SXA9,Crossover junction endonuclease MUS81 (EC 3.1.22.-),Crossover junction endonuclease MUS81 (EC 3.1.22.-),GO:0003677; GO:0006310; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA recombination; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF02732;,,,,,,,,,MUS81_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA recombination [GO:0006310]; DNA repair [GO:0006281] comp137373_c3_seq1,652,45.092,0.31194838,2,0,,4.00E-85,O09174,Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase),Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase),GO:0008111; GO:0006699; GO:0006631; GO:0008300; GO:0005739; GO:0005777,alpha-methylacyl-CoA racemase activity; bile acid biosynthetic process; fatty acid metabolic process; isoprenoid catabolic process; mitochondrion; peroxisome,PF02515;,,,,,,,,,AMACR_MOUSE,Mus musculus (Mouse),bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; isoprenoid catabolic process [GO:0008300] comp137373_c3_seq5,1895,38.8391,0.41111696,160,431,,1.00E-144,P70473,Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-arylpropionyl-CoA epimerase) (2-methylacyl-CoA racemase),Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-arylpropionyl-CoA epimerase) (2-methylacyl-CoA racemase),GO:0008111; GO:0006699; GO:0006631; GO:0005739; GO:0005777,alpha-methylacyl-CoA racemase activity; bile acid biosynthetic process; fatty acid metabolic process; mitochondrion; peroxisome,PF02515;,9.00E-27,CHOYP_AMACR.1.1,,,,,,,AMACR_RAT,Rattus norvegicus (Rat),bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631] comp137374_c0_seq2,1152,38.8021,0.5651965,96,173,,4.00E-111,Q9D172,"ES1 protein homolog, mitochondrial","ES1 protein homolog, mitochondrial",GO:0005739,mitochondrion,,3.00E-80,CHOYP_LOC100692418.1.1,,,,,,,ES1_MOUSE,Mus musculus (Mouse), comp137375_c0_seq2,1209,37.5517,0.39968938,27,916,,4.00E-30,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,,,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp137378_c1_seq3,813,42.4354,0.90401968,0,15,,4.00E-60,Q9UA35,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),GO:0016021; GO:0005415,integral to membrane; nucleoside:sodium symporter activity,PF07670;PF07662;PF01773;,,,,,,,,,S28A3_EPTST,Eptatretus stoutii (Pacific hagfish), comp137378_c1_seq4,1023,43.695,0.9295579,21,175,,7.00E-59,Q9UA35,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),GO:0016021; GO:0005415,integral to membrane; nucleoside:sodium symporter activity,PF07670;PF07662;PF01773;,8.00E-56,CHOYP_LOC574602.1.1,,,,,,,S28A3_EPTST,Eptatretus stoutii (Pacific hagfish), comp137378_c1_seq5,826,42.0097,0.90788556,0,40,,6.00E-55,Q9MZT2,Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1),Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1),GO:0016021; GO:0001882; GO:0005415; GO:0005886,integral to membrane; nucleoside binding; nucleoside:sodium symporter activity; plasma membrane,PF07670;PF07662;PF01773;,,,,,,,,,S28A1_RABIT,Oryctolagus cuniculus (Rabbit), comp137378_c2_seq2,1642,42.6309,0.82110321,0,4,,3.00E-74,Q78EG7,Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1),Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1),GO:0007049; GO:0005769; GO:0005783; GO:0007275; GO:0005634; GO:0005886; GO:0004725; GO:0005819,cell cycle; early endosome; endoplasmic reticulum; multicellular organismal development; nucleus; plasma membrane; protein tyrosine phosphatase activity; spindle,PF00782;,1.00E-105,CHOYP_ISCW_ISCW015996.1.1,,,,,,,TP4A1_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335] comp137378_c2_seq3,1806,41.9158,0.83569502,11,3,,,,,,,,,2.00E-105,CHOYP_ISCW_ISCW015996.1.1,,,,,,,,, comp137388_c0_seq1,2933,34.3334,0.60817993,100,694,,,,,,,,,1.00E-14,CHOYP_contig_045248,,,,,,,,, comp137388_c0_seq5,2896,34.0124,0.60514537,31,123,,,,,,,,,1.00E-14,CHOYP_contig_045248,,,,,,,,, comp137389_c0_seq1,1515,41.7162,0.60158756,18,271,,1.00E-21,Q8IRR5,NAD-dependent protein deacetylase Sirt4 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 4),NAD-dependent protein deacylase Sirt4 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 4),GO:0070403; GO:0016787; GO:0046872; GO:0005759,NAD+ binding; hydrolase activity; metal ion binding; mitochondrial matrix,PF02146;,,,,,,,,,SIR4_DROME,Drosophila melanogaster (Fruit fly),histone deacetylation [GO:0016575]; protein ADP-ribosylation [GO:0006471] comp137389_c0_seq2,1453,41.5692,0.55003178,33,176,,3.00E-134,E2RDZ6,"NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)","NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)",GO:0070403; GO:0005758; GO:0005759; GO:0006476; GO:0036054; GO:0036055; GO:0008270,NAD+ binding; mitochondrial intermembrane space; mitochondrial matrix; protein deacetylation; protein-malonyllysine demalonylase activity; protein-succinyllysine desuccinylase activity; zinc ion binding,PF02146;,3.00E-43,CHOYP_LOC100533524.1.1,,,,,,,SIR5_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),negative regulation of reactive oxygen species metabolic process [GO:2000378]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566] comp137390_c0_seq1,1139,33.8016,0.4315383,109,337,,8.00E-11,G5EBU4,Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),GO:0007411; GO:0046872; GO:0000122; GO:0005634; GO:0045773; GO:0043565; GO:0003700; GO:0006351,"axon guidance; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of axon extension; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF13912;,,,,,,,,,ZAG1_CAEEL,Caenorhabditis elegans,"axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]" comp137392_c0_seq2,1648,51.2743,0.40128481,34,56,,2.00E-09,Q961D9,Protein BCL9 homolog (Protein legless),Protein BCL9 homolog (Protein legless),GO:0016055; GO:0008587; GO:0005634; GO:0030177; GO:0045944; GO:0007367; GO:0006351,"Wnt receptor signaling pathway; imaginal disc-derived wing margin morphogenesis; nucleus; positive regulation of Wnt receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; segment polarity determination; transcription, DNA-dependent",PF11502;,,,,,,,,,BCL9_DROME,Drosophila melanogaster (Fruit fly),"imaginal disc-derived wing margin morphogenesis [GO:0008587]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; segment polarity determination [GO:0007367]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp137396_c0_seq1,1173,40.8355,0.53384208,179,1497,,8.00E-64,Q499R4,"YrdC domain-containing protein, mitochondrial (Ischemia/reperfusion-inducible protein homolog)","YrdC domain-containing protein, mitochondrial (Ischemia/reperfusion-inducible protein homolog)",GO:0003725; GO:0016020; GO:0005739; GO:0051051,double-stranded RNA binding; membrane; mitochondrion; negative regulation of transport,PF01300;,2.00E-45,CHOYP_NEMVEDRAFT_V1G161176.1.1,,,,,,,YRDC_RAT,Rattus norvegicus (Rat),negative regulation of transport [GO:0051051]; regulation of translational fidelity [GO:0006450]; tRNA threonylcarbamoyladenosine modification [GO:0002949] comp137398_c0_seq1,1836,39.7603,0.7232888,257,2340,,6.00E-07,Q5U3U0,Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-),Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-),GO:0051213; GO:0046872,dioxygenase activity; metal ion binding,PF05721;,3.00E-51,CHOYP_LOC100640001.1.2,2.00E-38,ruditapes_c16185,,,,,PHYD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp137404_c1_seq3,467,35.9743,0.5398727,0,0,,7.00E-28,Q8IY51,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_HUMAN,Homo sapiens (Human), comp137405_c0_seq1,1145,37.3799,0.30029502,0,0,,,,,,,,,4.00E-35,CHOYP_DGKD.2.2,,,,,,,,, comp137405_c0_seq2,1107,37.3984,0.31029921,5,7,,3.00E-11,Q9UPX8,SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1),SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1),GO:0030160; GO:0016324; GO:0031526; GO:0030054; GO:0060170; GO:0005737; GO:0043197; GO:0030426; GO:0035556; GO:0035255; GO:0043025; GO:0001917; GO:0001750; GO:0014069; GO:0045211,GKAP/Homer scaffold activity; apical plasma membrane; brush border membrane; cell junction; cilium membrane; cytoplasm; dendritic spine; growth cone; intracellular signal transduction; ionotropic glutamate receptor binding; neuronal cell body; photoreceptor inner segment; photoreceptor outer segment; postsynaptic density; postsynaptic membrane,PF00595;PF00536;PF07653;,,,,,,,,,SHAN2_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; learning [GO:0007612]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625] comp137405_c0_seq4,3223,45.1753,0.52525258,158,91,,0,Q16760,Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta),Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta),GO:0005524; GO:0003951; GO:0016049; GO:0005737; GO:0016023; GO:0019992; GO:0004143; GO:0046339; GO:0006897; GO:0007173; GO:0046872; GO:0007275; GO:0005543; GO:0005886; GO:0030168; GO:0046982; GO:0042803; GO:0051260; GO:0007205; GO:0015031; GO:0010033; GO:0019932,ATP binding; NAD+ kinase activity; cell growth; cytoplasm; cytoplasmic membrane-bounded vesicle; diacylglycerol binding; diacylglycerol kinase activity; diacylglycerol metabolic process; endocytosis; epidermal growth factor receptor signaling pathway; metal ion binding; multicellular organismal development; phospholipid binding; plasma membrane; platelet activation; protein heterodimerization activity; protein homodimerization activity; protein homooligomerization; protein kinase C-activating G-protein coupled receptor signaling pathway; protein transport; response to organic substance; second-messenger-mediated signaling,PF00130;PF00609;PF00781;PF00169;PF07647;,0,CHOYP_DGKD.2.2,,,,,,,DGKD_HUMAN,Homo sapiens (Human),cell growth [GO:0016049]; diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165] comp137405_c0_seq6,703,43.67,0.72652366,0,0,,2.00E-88,Q64398,Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase eta) (DGK-eta),Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase eta) (DGK-eta),GO:0005524; GO:0003951; GO:0005737; GO:0004143; GO:0035556; GO:0046872; GO:0005543; GO:0005886; GO:0007205,ATP binding; NAD+ kinase activity; cytoplasm; diacylglycerol kinase activity; intracellular signal transduction; metal ion binding; phospholipid binding; plasma membrane; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF00609;PF00781;PF00169;,6.00E-68,CHOYP_DGKD.1.2,,,,,,,DGKH_MESAU,Mesocricetus auratus (Golden hamster),intracellular signal transduction [GO:0035556]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205] comp137406_c2_seq1,1203,42.6434,0.56766579,50,331,,1.00E-30,O93530,Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-) (Focus-forming activity 1) (FFA-1),Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-) (Focus-forming activity 1) (FFA-1),GO:0008408; GO:0005524; GO:0043140; GO:0003677; GO:0006259; GO:0006310; GO:0006281; GO:0006260; GO:0000287; GO:0030145; GO:0005634,3'-5' exonuclease activity; ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA binding; DNA metabolic process; DNA recombination; DNA repair; DNA replication; magnesium ion binding; manganese ion binding; nucleus,PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;,1.00E-22,CHOYP_LOC100179894.1.1,,,,,,,WRN_XENLA,Xenopus laevis (African clawed frog),DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp137408_c0_seq1,708,43.5028,0.45536379,0,14,,8.00E-06,O74529,Uncharacterized methyltransferase C70.08c (EC 2.1.1.-),Uncharacterized methyltransferase C70.08c (EC 2.1.1.-),GO:0005829; GO:0008168; GO:0005634,cytosol; methyltransferase activity; nucleus,PF08241;,,,,,,,,,YJ48_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),methylation [GO:0032259] comp137408_c0_seq2,318,46.8553,0.52257524,7,52,,3.00E-07,B3PI89,Biotin biosynthesis bifunctional protein BioHC [Includes: Carboxylesterase BioH (EC 3.1.1.1) (Biotin synthesis protein BioH); Malonyl-[acyl-carrier protein] O-methyltransferase (Malonyl-ACP O-methyltransferase) (EC 2.1.1.197) (Biotin synthesis protein BioC)],Biotin biosynthesis bifunctional protein BioHC [Includes: Carboxylesterase BioH (EC 3.1.1.1) (Biotin synthesis protein BioH); Malonyl-[acyl-carrier protein] O-methyltransferase (Malonyl-ACP O-methyltransferase) (EC 2.1.1.197) (Biotin synthesis protein BioC)],GO:0009102; GO:0010340; GO:0004091; GO:0004141,biotin biosynthetic process; carboxyl-O-methyltransferase activity; carboxylesterase activity; dethiobiotin synthase activity,PF12697;PF08241;,,,,,,,,,BIOHC_CELJU,Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa),biotin biosynthetic process [GO:0009102] comp137408_c0_seq5,1322,40.8472,0.50464823,0,9,,8.00E-122,Q9FR44,Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103),Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103) (Protein XIPOTL 1),GO:0042425; GO:0005829; GO:0006656; GO:0000234; GO:0009555; GO:0009860; GO:0010183; GO:0048528,choline biosynthetic process; cytosol; phosphatidylcholine biosynthetic process; phosphoethanolamine N-methyltransferase activity; pollen development; pollen tube growth; pollen tube guidance; post-embryonic root development,PF08241;,,,,,,,,,PEAM1_ARATH,Arabidopsis thaliana (Mouse-ear cress),choline biosynthetic process [GO:0042425]; phosphatidylcholine biosynthetic process [GO:0006656]; pollen development [GO:0009555]; pollen tube growth [GO:0009860]; pollen tube guidance [GO:0010183]; post-embryonic root development [GO:0048528]; unidimensional cell growth [GO:0009826] comp137408_c0_seq6,1302,40.4762,0.48051421,0,0,,7.00E-112,Q9FR44,Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103),Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103) (Protein XIPOTL 1),GO:0042425; GO:0005829; GO:0006656; GO:0000234; GO:0009555; GO:0009860; GO:0010183; GO:0048528,choline biosynthetic process; cytosol; phosphatidylcholine biosynthetic process; phosphoethanolamine N-methyltransferase activity; pollen development; pollen tube growth; pollen tube guidance; post-embryonic root development,PF08241;,2.00E-108,CHOYP_BRAFLDRAFT_118790.1.1,,,,,,,PEAM1_ARATH,Arabidopsis thaliana (Mouse-ear cress),choline biosynthetic process [GO:0042425]; phosphatidylcholine biosynthetic process [GO:0006656]; pollen development [GO:0009555]; pollen tube growth [GO:0009860]; pollen tube guidance [GO:0010183]; post-embryonic root development [GO:0048528]; unidimensional cell growth [GO:0009826] comp137408_c0_seq7,738,43.2249,0.49853266,0,0,,9.00E-06,O74529,Uncharacterized methyltransferase C70.08c (EC 2.1.1.-),Uncharacterized methyltransferase C70.08c (EC 2.1.1.-),GO:0005829; GO:0008168; GO:0005634,cytosol; methyltransferase activity; nucleus,PF08241;,,,,,,,,,YJ48_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),methylation [GO:0032259] comp137411_c0_seq1,1279,45.0352,0.64453572,63,236,,5.00E-10,Q96B36,Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate),Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate),GO:0038095; GO:0005829; GO:0007173; GO:0008543; GO:0045087; GO:0032007; GO:0045792; GO:0006469; GO:0048011; GO:0048015; GO:0043523,Fc-epsilon receptor signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; negative regulation of TOR signaling cascade; negative regulation of cell size; negative regulation of protein kinase activity; neurotrophin TRK receptor signaling pathway; phosphatidylinositol-mediated signaling; regulation of neuron apoptotic process,PF15798;,,,2.00E-18,ruditapes_c21031,,,,,AKTS1_HUMAN,Homo sapiens (Human),negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; neurotrophin TRK receptor signaling pathway [GO:0048011]; regulation of cellular response to heat [GO:1900034]; regulation of neuron apoptotic process [GO:0043523] comp137412_c0_seq2,1532,40.8616,0.32917192,101,424,,0,Q64323,N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A),N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A),GO:0006506; GO:0005789; GO:0000506; GO:0016021; GO:0016757,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to membrane; transferase activity, transferring glycosyl groups",PF00534;PF08288;,4.00E-131,CHOYP_PIGA.1.1,,,,,,,PIGA_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp137416_c0_seq1,2937,42.4583,0.51391389,78,604,,6.00E-179,Q9VXE5,Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1) (Protein mushroom bodies tiny) (p21-activated kinase-related protein),Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1) (Protein mushroom bodies tiny) (p21-activated kinase-related protein),GO:0005524; GO:0007030; GO:0000187; GO:0005913; GO:0001751; GO:0007010; GO:0046331; GO:0016319; GO:0045792; GO:0005886; GO:0045315; GO:0004702,ATP binding; Golgi organization; activation of MAPK activity; cell-cell adherens junction; compound eye photoreceptor cell differentiation; cytoskeleton organization; lateral inhibition; mushroom body development; negative regulation of cell size; plasma membrane; positive regulation of compound eye photoreceptor development; receptor signaling protein serine/threonine kinase activity,PF00786;PF00069;,0,CHOYP_PAK7.1.1,3.00E-33,ruditapes_c9388,,,,,PAKM_DROME,Drosophila melanogaster (Fruit fly),activation of MAPK activity [GO:0000187]; compound eye development [GO:0048749]; compound eye photoreceptor cell differentiation [GO:0001751]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; lateral inhibition [GO:0046331]; mushroom body development [GO:0016319]; negative regulation of cell size [GO:0045792]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of compound eye photoreceptor development [GO:0045315]; protein phosphorylation [GO:0006468]; regulation of cell-cell adhesion mediated by cadherin [GO:2000047] comp137422_c0_seq2,979,38.2022,0.56107464,37,104,,2.00E-10,Q9H840,Gem-associated protein 7 (Gemin-7) (SIP3),Gem-associated protein 7 (Gemin-7) (SIP3),GO:0097504; GO:0032797; GO:0005829; GO:0034660; GO:0016604; GO:0005681; GO:0000387,Gemini of coiled bodies; SMN complex; cytosol; ncRNA metabolic process; nuclear body; spliceosomal complex; spliceosomal snRNP assembly,PF11095;,,,,,,,,,GEMI7_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; spliceosomal snRNP assembly [GO:0000387]" comp137424_c0_seq1,1614,41.6357,0.54441282,95,362,,4.00E-99,Q9CYC6,m7GpppN-mRNA hydrolase (EC 3.6.1.62) (mRNA-decapping enzyme 2),m7GpppN-mRNA hydrolase (EC 3.6.1.62) (mRNA-decapping enzyme 2),GO:0016442; GO:0003723; GO:0000932; GO:0071044; GO:0050072; GO:0030145; GO:0000184; GO:0005634,"RISC complex; RNA binding; cytoplasmic mRNA processing body; histone mRNA catabolic process; m7G(5')pppN diphosphatase activity; manganese ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus",PF05026;PF00293;,4.00E-94,CHOYP_DCP2.1.1,,,,,,,DCP2_MOUSE,Mus musculus (Mouse),"deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; histone mRNA catabolic process [GO:0071044]; mRNA catabolic process [GO:0006402]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp137426_c0_seq1,4102,40.4193,0.48199709,51,15,,2.00E-46,Q6P132,Tax1-binding protein 1 homolog B,Tax1-binding protein 1 homolog B,GO:0006915,apoptotic process,PF07888;,,,,,,,,,TXB1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915] comp137426_c0_seq3,3642,39.2367,0.52274362,2,38,,1.00E-46,Q6P132,Tax1-binding protein 1 homolog B,Tax1-binding protein 1 homolog B,GO:0006915,apoptotic process,PF07888;,3.00E-54,CHOYP_IQCA1.1.3,,,,,,,TXB1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915] comp137428_c0_seq1,2054,41.7235,0.51800111,155,39,,8.00E-07,O15050,TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),GO:0005524; GO:0016787,ATP binding; hydrolase activity,PF00580;,,,,,,,,,TRNK1_HUMAN,Homo sapiens (Human), comp137428_c2_seq2,3204,42.6966,0.46908467,76,17,,1.00E-74,O15050,TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog),GO:0005524; GO:0016787,ATP binding; hydrolase activity,PF00580;,3.00E-67,CHOYP_TRNK1.6.6,,,,,,,TRNK1_HUMAN,Homo sapiens (Human), comp137428_c2_seq3,1016,47.6378,0.52571775,16,11,,,,,,,,,2.00E-64,CHOYP_TRNK1.6.6,,,,,,,,, comp137428_c2_seq4,2529,41.5579,0.36814732,21,9,,1.00E-38,Q5T1R4,Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Zinc finger protein ZAS3),Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Zinc finger protein ZAS3),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0045893; GO:0035914; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; skeletal muscle cell differentiation; transcription, DNA-dependent",,,,,,,,,,ZEP3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366]" comp137428_c2_seq5,1276,42.163,0.28426357,0,0,,4.00E-39,P15822,Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1),Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1),GO:0003677; GO:0005737; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",,,,,,,,,,ZEP1_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366] comp137430_c1_seq1,2347,45.4197,0.81061368,8,8,,3.00E-25,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp137433_c0_seq1,1193,33.3613,0.54719085,101,591,,1.00E-54,Q9CQZ7,DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III subunit C11) (RPC11),DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III subunit C11) (RPC11),GO:0003677; GO:0003899; GO:0051607; GO:0045087; GO:0005634; GO:0006351; GO:0008270,"DNA binding; DNA-directed RNA polymerase activity; defense response to virus; innate immune response; nucleus; transcription, DNA-dependent; zinc ion binding",PF02150;PF01096;,2.00E-52,CHOYP_POLR3K.1.1,,,,,,,RPC10_MOUSE,Mus musculus (Mouse),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; termination of RNA polymerase III transcription [GO:0006386] comp137436_c4_seq1,1565,36.1661,1.04974431,2,43,,,,,,,,,5.00E-16,CHOYP_SMP_043120.1.1,,,,,,,,, comp137436_c4_seq11,1069,40.0374,0.98440461,0,0,,,,,,,,,2.00E-12,CHOYP_LOC100181607.2.2,,,,,,,,, comp137436_c4_seq2,1661,37.3871,1.04375169,53,164,,9.00E-06,Q57951,Universal stress protein MJ0531 (USP MJ0531),Universal stress protein MJ0531 (USP MJ0531),GO:0006950,response to stress,PF00582;,6.00E-22,CHOYP_NEMVEDRAFT_V1G244537.1.3,2.00E-31,ruditapes_c3215,,,,,Y531_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),response to stress [GO:0006950] comp137436_c4_seq3,1085,40,0.9716059,0,25,,,,,,,,,,,1.00E-13,ruditapes_c17805,,,,,,, comp137436_c4_seq4,1621,35.7804,1.02707327,0,0,,,,,,,,,3.00E-12,CHOYP_LOC100181607.2.2,,,,,,,,, comp137436_c4_seq7,1717,36.9831,1.02567199,92,543,,,,,,,,,7.00E-21,CHOYP_NEMVEDRAFT_V1G236658.2.6,4.00E-35,ruditapes2_c369,,,,,,, comp137436_c4_seq9,1015,40.9852,1.00077491,0,0,,,,,,,,,3.00E-16,CHOYP_SMP_043120.1.1,3.00E-14,ruditapes_c15373,,,,,,, comp137437_c0_seq1,1879,38.2118,0.60173167,34,846,,6.00E-180,Q91447,Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment),Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment),GO:0005524; GO:0005737; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:0005816,ATP binding; cytoplasm; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; spindle pole body,PF00069;,0,CHOYP_LOC100742289.1.1,,,,,,,MP2K1_SERCA,Serinus canaria (Island canary) (Fringilla canaria), comp137439_c0_seq1,429,44.289,0.50345666,37,88,,,,,,,,,2.00E-21,CHOYP_CIT.1.2,,,,,,,,, comp137439_c0_seq2,754,44.0318,0.50870387,236,482,,,,,,,,,5.00E-19,CHOYP_CIT.2.2,,,,,,,,, comp137441_c1_seq3,2646,39.2668,0.43567133,102,707,,1.00E-155,P0CP26,Nucleolar protein 58,Nucleolar protein 58,GO:0005730; GO:0006364; GO:0030529,nucleolus; rRNA processing; ribonucleoprotein complex,PF01798;PF08156;,0,CHOYP_NOL5.1.1,,,,,,,NOP58_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),rRNA modification [GO:0000154] comp137441_c1_seq4,2199,40.2456,0.48762897,40,326,,0,Q9Y2X3,Nucleolar protein 58 (Nucleolar protein 5),Nucleolar protein 58 (Nucleolar protein 5),GO:0015030; GO:0031428; GO:0016049; GO:0005737; GO:0070761; GO:0006364; GO:0006608; GO:0030515,Cajal body; box C/D snoRNP complex; cell growth; cytoplasm; pre-snoRNP complex; rRNA processing; snRNP protein import into nucleus; snoRNA binding,PF01798;PF08156;,0,CHOYP_NOL5.1.1,8.00E-89,ruditapes_c17007,,,,,NOP58_HUMAN,Homo sapiens (Human),cell growth [GO:0016049]; protein sumoylation [GO:0016925]; rRNA modification [GO:0000154]; rRNA processing [GO:0006364]; snoRNA localization [GO:0048254]; snRNP protein import into nucleus [GO:0006608] comp137443_c2_seq1,3592,37.4165,0.94176829,2,0,,6.00E-38,Q8BLY1,SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1),SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1),GO:0005604; GO:0005509; GO:0030154; GO:0050840; GO:0030198; GO:0001654; GO:0060173; GO:0010811; GO:0007165,basement membrane; calcium ion binding; cell differentiation; extracellular matrix binding; extracellular matrix organization; eye development; limb development; positive regulation of cell-substrate adhesion; signal transduction,PF07648;PF10591;PF00086;,,,,,,,,,SMOC1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; limb development [GO:0060173]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165] comp137443_c2_seq2,3534,37.0685,0.93382985,0,0,,3.00E-37,Q9H4F8,SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1),SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1),GO:0005604; GO:0005509; GO:0030154; GO:0050840; GO:0030198; GO:0001654; GO:0060173; GO:0010811; GO:0045667; GO:0007165,basement membrane; calcium ion binding; cell differentiation; extracellular matrix binding; extracellular matrix organization; eye development; limb development; positive regulation of cell-substrate adhesion; regulation of osteoblast differentiation; signal transduction,PF07648;PF10591;PF00086;,,,,,,,,,SMOC1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165] comp137443_c2_seq3,3640,37.4451,0.92570779,6,0,,2.00E-29,Q9H3U7,SPARC-related modular calcium-binding protein 2 (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2),SPARC-related modular calcium-binding protein 2 (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2),GO:0005604; GO:0005509; GO:0030198; GO:0008201; GO:0005614; GO:0010811; GO:0007165,basement membrane; calcium ion binding; extracellular matrix organization; heparin binding; interstitial matrix; positive regulation of cell-substrate adhesion; signal transduction,PF07648;PF10591;PF00086;,,,,,,,,,SMOC2_HUMAN,Homo sapiens (Human),extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]; signal transduction [GO:0007165] comp137443_c2_seq4,2491,35.3673,0.8487384,0,0,,7.00E-38,Q9H4F8,SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1),SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1),GO:0005604; GO:0005509; GO:0030154; GO:0050840; GO:0030198; GO:0001654; GO:0060173; GO:0010811; GO:0045667; GO:0007165,basement membrane; calcium ion binding; cell differentiation; extracellular matrix binding; extracellular matrix organization; eye development; limb development; positive regulation of cell-substrate adhesion; regulation of osteoblast differentiation; signal transduction,PF07648;PF10591;PF00086;,,,,,,,,,SMOC1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165] comp137443_c2_seq6,2543,35.8238,0.84680464,0,0,,9.00E-41,Q8BLY1,SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1),SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1),GO:0005604; GO:0005509; GO:0030154; GO:0050840; GO:0030198; GO:0001654; GO:0060173; GO:0010811; GO:0007165,basement membrane; calcium ion binding; cell differentiation; extracellular matrix binding; extracellular matrix organization; eye development; limb development; positive regulation of cell-substrate adhesion; signal transduction,PF07648;PF10591;PF00086;,,,,,,,,,SMOC1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; limb development [GO:0060173]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165] comp137443_c2_seq8,597,43.8861,1.20919457,0,0,,1.00E-19,Q9H4F8,SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1),SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1),GO:0005604; GO:0005509; GO:0030154; GO:0050840; GO:0030198; GO:0001654; GO:0060173; GO:0010811; GO:0045667; GO:0007165,basement membrane; calcium ion binding; cell differentiation; extracellular matrix binding; extracellular matrix organization; eye development; limb development; positive regulation of cell-substrate adhesion; regulation of osteoblast differentiation; signal transduction,PF07648;PF10591;PF00086;,,,,,,,,,SMOC1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165] comp137445_c0_seq1,418,39.4737,0.43362164,5,42,,3.00E-13,Q9BXA9,Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3),Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3),GO:0003677; GO:0035136; GO:0035137; GO:0046872; GO:0045879; GO:0005634; GO:0021891; GO:0006355; GO:0006351,"DNA binding; forelimb morphogenesis; hindlimb morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; nucleus; olfactory bulb interneuron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,SALL3_HUMAN,Homo sapiens (Human),"forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; neurogenesis [GO:0022008]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]" comp137445_c4_seq1,687,39.0102,0.31041744,2,41,,8.00E-12,O00110,Putative transcription factor ovo-like protein 3,Putative transcription factor ovo-like protein 3,GO:0046872; GO:0003676; GO:0005634; GO:0003700; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,,,,,,,,,OVOL3_HUMAN,Homo sapiens (Human),transcription from RNA polymerase II promoter [GO:0006366] comp137445_c4_seq10,534,31.8352,0.37911131,0,0,,6.00E-11,Q8N1W2,Zinc finger protein 710,Zinc finger protein 710,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZN710_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp137445_c4_seq14,653,37.0597,0.46343646,1,44,,2.00E-11,Q8BIQ8,Zinc finger protein 770,Zinc finger protein 770,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF13912;,,,,,,,,,ZN770_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp137445_c4_seq2,821,41.6565,0.44873961,14,182,,9.00E-12,Q05516,Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF),Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF),GO:0003677; GO:0016605; GO:0009952; GO:0006915; GO:0051216; GO:0007417; GO:0035116; GO:0009880; GO:0035136; GO:0048133; GO:0001823; GO:0046872; GO:0030099; GO:0008285; GO:0045638; GO:0045892; GO:0016607; GO:0043065; GO:0061036; GO:0032332; GO:0045600; GO:0045778; GO:0045893; GO:0042803; GO:0016567; GO:0006351; GO:0017053,"DNA binding; PML body; anterior/posterior pattern specification; apoptotic process; cartilage development; central nervous system development; embryonic hindlimb morphogenesis; embryonic pattern specification; forelimb morphogenesis; male germ-line stem cell division; mesonephros development; metal ion binding; myeloid cell differentiation; negative regulation of cell proliferation; negative regulation of myeloid cell differentiation; negative regulation of transcription, DNA-dependent; nuclear speck; positive regulation of apoptotic process; positive regulation of cartilage development; positive regulation of chondrocyte differentiation; positive regulation of fat cell differentiation; positive regulation of ossification; positive regulation of transcription, DNA-dependent; protein homodimerization activity; protein ubiquitination; transcription, DNA-dependent; transcriptional repressor complex",PF00651;PF13912;,,,,,,,,,ZBT16_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; cartilage development [GO:0051216]; central nervous system development [GO:0007417]; embryonic digit morphogenesis [GO:0042733]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic pattern specification [GO:0009880]; forelimb morphogenesis [GO:0035136]; hemopoiesis [GO:0030097]; male germ-line stem cell asymmetric division [GO:0048133]; mesonephros development [GO:0001823]; myeloid cell differentiation [GO:0030099]; negative regulation of cell proliferation [GO:0008285]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of ossification [GO:0045778]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to nucleus [GO:0034504]; protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]" comp137445_c4_seq4,568,34.507,0.17820287,0,5,,2.00E-12,P18714,Gastrula zinc finger protein xFG20-1 (XlCGF20.1),Gastrula zinc finger protein xFG20-1 (XlCGF20.1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG20_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137445_c4_seq5,446,46.1883,0.38742491,8,120,,2.00E-10,Q86UZ6,Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340),Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340),GO:0046872; GO:2001199; GO:0030853; GO:0045650; GO:0045656; GO:0003676; GO:0005634; GO:2001200; GO:0006355; GO:0006351,"metal ion binding; negative regulation of dendritic cell differentiation; negative regulation of granulocyte differentiation; negative regulation of macrophage differentiation; negative regulation of monocyte differentiation; nucleic acid binding; nucleus; positive regulation of dendritic cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT46_HUMAN,Homo sapiens (Human),"negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137445_c4_seq6,965,37.7202,0.62420449,8,213,,2.00E-12,A6NFI3,Zinc finger protein 316,Zinc finger protein 316,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN316_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137445_c4_seq8,628,39.9682,0.53069968,4,113,,2.00E-12,P41696,Asparagine-rich zinc finger protein AZF1,Asparagine-rich zinc finger protein AZF1,GO:0000978; GO:0001077; GO:0071322; GO:0005829; GO:0046872; GO:0005634; GO:0060237,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to carbohydrate stimulus; cytosol; metal ion binding; nucleus; regulation of fungal-type cell wall organization,PF13912;,,,,,,,,,AZF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp137446_c3_seq1,1199,41.5346,1.10327996,14,45,,4.00E-30,Q08830,Fibrinogen-like protein 1 (HP-041) (Hepassocin) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1),Fibrinogen-like protein 1 (HP-041) (Hepassocin) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1),GO:0005577; GO:0035634,fibrinogen complex; response to stilbenoid,PF00147;,,,2.00E-12,ruditapes_lrc36550,,,,,FGL1_HUMAN,Homo sapiens (Human), comp137446_c3_seq2,1352,41.568,0.99388329,32,465,,2.00E-29,Q3SZZ7,Fibrinogen-like protein 1,Fibrinogen-like protein 1,GO:0005576,extracellular region,PF00147;,,,8.00E-17,ruditapes_lrc32148,,,,,FGL1_BOVIN,Bos taurus (Bovine), comp137451_c1_seq10,514,42.9961,0.12845077,0,0,,2.00E-06,Q9PVV4,Pericentriolar material 1 protein (PCM-1) (xPCM-1),Pericentriolar material 1 protein (PCM-1) (xPCM-1),GO:0034451; GO:0042384,centriolar satellite; cilium assembly,PF15717;,,,,,,,,,PCM1_XENLA,Xenopus laevis (African clawed frog),cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp137451_c1_seq5,527,43.074,0.12472486,0,0,,8.00E-07,Q9PVV4,Pericentriolar material 1 protein (PCM-1) (xPCM-1),Pericentriolar material 1 protein (PCM-1) (xPCM-1),GO:0034451; GO:0042384,centriolar satellite; cilium assembly,PF15717;,,,,,,,,,PCM1_XENLA,Xenopus laevis (African clawed frog),cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp137451_c1_seq6,485,44.1237,0.13026054,0,0,,2.00E-06,Q15154,Pericentriolar material 1 protein (PCM-1) (hPCM-1),Pericentriolar material 1 protein (PCM-1) (hPCM-1),GO:0000086; GO:0034451; GO:0051297; GO:0042384; GO:0005829; GO:0042802; GO:0022027; GO:0034453; GO:0034454; GO:0050768; GO:0097150; GO:0031965; GO:0000242; GO:0071539,G2/M transition of mitotic cell cycle; centriolar satellite; centrosome organization; cilium assembly; cytosol; identical protein binding; interkinetic nuclear migration; microtubule anchoring; microtubule anchoring at centrosome; negative regulation of neurogenesis; neuronal stem cell maintenance; nuclear membrane; pericentriolar material; protein localization to centrosome,PF15717;,,,,,,,,,PCM1_HUMAN,Homo sapiens (Human),centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; G2/M transition of mitotic cell cycle [GO:0000086]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp137453_c0_seq1,728,34.8901,0.77008783,0,0,,,,,,,,,,,8.00E-14,ruditapes_lrc10072,,,,,,, comp137453_c0_seq2,947,38.226,0.81144625,0,0,,,,,,,,,,,3.00E-21,ruditapes2_c2581,,,,,,, comp137453_c0_seq5,777,34.8777,0.76399472,0,0,,,,,,,,,,,4.00E-24,ruditapes2_c3020,,,,,,, comp137461_c1_seq1,2780,40.0719,0.38457234,638,2494,,1.00E-24,Q5R5X0,Pinin,Pinin,GO:0003677; GO:0008380; GO:0030057; GO:0006397; GO:0016607; GO:0006355; GO:0005681; GO:0006351,"DNA binding; RNA splicing; desmosome; mRNA processing; nuclear speck; regulation of transcription, DNA-dependent; spliceosomal complex; transcription, DNA-dependent",PF04696;PF04697;,2.00E-12,CHOYP_PININ.1.1,,,,,,,PININ_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp137467_c0_seq2,715,42.2378,0.47782271,8,6,,2.00E-12,O00461,"Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)","Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)",GO:0032580; GO:0005796; GO:0005801; GO:0030139; GO:0010008; GO:0016021; GO:0005634; GO:0006810,Golgi cisterna membrane; Golgi lumen; cis-Golgi network; endocytic vesicle; endosome membrane; integral to membrane; nucleus; transport,,,,,,,,,,GOLI4_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp137467_c0_seq3,778,42.4165,0.49104609,7,10,,3.00E-12,O00461,"Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)","Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)",GO:0032580; GO:0005796; GO:0005801; GO:0030139; GO:0010008; GO:0016021; GO:0005634; GO:0006810,Golgi cisterna membrane; Golgi lumen; cis-Golgi network; endocytic vesicle; endosome membrane; integral to membrane; nucleus; transport,,,,,,,,,,GOLI4_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp137469_c0_seq2,1658,39.0229,0.42086072,49,212,,4.00E-114,Q8VCL5,Solute carrier family 17 member 9,Solute carrier family 17 member 9,GO:0006887; GO:0016021; GO:0055085; GO:0005215,exocytosis; integral to membrane; transmembrane transport; transporter activity,PF07690;,,,,,,,,,S17A9_MOUSE,Mus musculus (Mouse),anion transport [GO:0006820]; exocytosis [GO:0006887]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; transmembrane transport [GO:0055085] comp137469_c0_seq4,1658,39.5054,0.4286413,10,30,,4.00E-110,Q8VCL5,Solute carrier family 17 member 9,Solute carrier family 17 member 9,GO:0006887; GO:0016021; GO:0055085; GO:0005215,exocytosis; integral to membrane; transmembrane transport; transporter activity,PF07690;,2.00E-96,CHOYP_LOC100371999.1.1,,,,,,,S17A9_MOUSE,Mus musculus (Mouse),anion transport [GO:0006820]; exocytosis [GO:0006887]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; transmembrane transport [GO:0055085] comp137471_c1_seq4,490,36.3265,0.32820992,37,205,,,,,,,,,,,3.00E-11,ruditapes_c6570,,,,,,, comp137477_c1_seq9,336,29.4643,0.99201888,0,0,,,,,,,,,,,1.00E-13,ruditapes_c22253,,,,,,, comp137484_c1_seq5,454,24.8899,0.71541228,142,188,,,,,,,,,,,6.00E-13,ruditapes_c21964,,,,,,, comp137484_c2_seq1,1485,42.0875,1.12668084,34,255,,1.00E-67,Q8BWB6,Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2),Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2),GO:0006893; GO:0015677; GO:0008823; GO:0005829; GO:0005769; GO:0006897; GO:0010008; GO:0097461; GO:0052851; GO:0030173; GO:0055072; GO:0046872; GO:0005886; GO:0045055; GO:0009725; GO:0030140; GO:0005215,Golgi to plasma membrane transport; copper ion import; cupric reductase activity; cytosol; early endosome; endocytosis; endosome membrane; ferric iron import into cell; ferric-chelate reductase (NADPH) activity; integral to Golgi membrane; iron ion homeostasis; metal ion binding; plasma membrane; regulated secretory pathway; response to hormone stimulus; trans-Golgi network transport vesicle; transporter activity,PF03807;PF01794;,,,8.00E-11,ruditapes_c10654,,,,,STEA2_MOUSE,Mus musculus (Mouse),copper ion import [GO:0015677]; endocytosis [GO:0006897]; ferric iron import into cell [GO:0097461]; Golgi to plasma membrane transport [GO:0006893]; iron ion homeostasis [GO:0055072]; oxidation-reduction process [GO:0055114]; regulated exocytosis [GO:0045055]; response to hormone [GO:0009725] comp137486_c0_seq1,1128,38.2092,0.46955207,5,105,,3.00E-13,Q20681,BTB and MATH domain-containing protein 38,BTB and MATH domain-containing protein 38,,,PF00651;PF00917;,,,,,,,,,BAT38_CAEEL,Caenorhabditis elegans, comp137488_c0_seq3,780,47.3077,0.50882576,54,19,,,,,,,,,7.00E-17,CHOYP_PKCB1.1.1,,,,,,,,, comp137488_c0_seq4,1487,41.6274,0.48411088,78,51,,1.00E-131,Q9ULU4,Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8),Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8),GO:0001106; GO:0005634; GO:0070491; GO:0008270,RNA polymerase II transcription corepressor activity; nucleus; repressing transcription factor binding; zinc ion binding,PF00439;PF12064;PF00855;,5.00E-117,CHOYP_PKCB1.1.1,,,,,,,PKCB1_HUMAN,Homo sapiens (Human),"modulation of excitatory postsynaptic potential [GO:0098815]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of filopodium assembly [GO:0051491]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of transcription, DNA-templated [GO:0006355]" comp137489_c0_seq3,1667,46.5507,0.41481397,0,0,,0,Q61493,DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0005694; GO:0046872; GO:0000166; GO:0005634; GO:0019985; GO:0016035,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; chromosome; metal ion binding; nucleotide binding; nucleus; translesion synthesis; zeta DNA polymerase complex",PF00136;PF03104;PF15735;PF14260;,,,,,,,,,DPOLZ_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276] comp137489_c0_seq4,1587,46.5658,0.43532654,0,0,,1.00E-27,P52342,DNA polymerase catalytic subunit (EC 2.7.7.7),DNA polymerase catalytic subunit (EC 2.7.7.7),GO:0003677; GO:0006260; GO:0003887; GO:0042025; GO:0000166,DNA binding; DNA replication; DNA-directed DNA polymerase activity; host cell nucleus; nucleotide binding,PF00136;PF03104;,1.00E-149,CHOYP_DPOLZ.1.1,,,,,,,DPOL_HHV7J,Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus),DNA replication [GO:0006260] comp137489_c0_seq8,924,46.7532,0.42295431,0,0,,1.00E-77,Q61493,DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0005694; GO:0046872; GO:0000166; GO:0005634; GO:0019985; GO:0016035,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; chromosome; metal ion binding; nucleotide binding; nucleus; translesion synthesis; zeta DNA polymerase complex",PF00136;PF03104;PF15735;PF14260;,,,,,,,,,DPOLZ_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276] comp137490_c0_seq2,1403,38.2038,0.41132833,166,279,,2.00E-64,Q9R088,"Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)","Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)",GO:0005524; GO:0009262; GO:0006264; GO:0005743; GO:0016773; GO:0004797,"ATP binding; deoxyribonucleotide metabolic process; mitochondrial DNA replication; mitochondrial inner membrane; phosphotransferase activity, alcohol group as acceptor; thymidine kinase activity",PF01712;,1.00E-49,CHOYP_NEMVEDRAFT_V1G200323.1.1,,,,,,,KITM_MOUSE,Mus musculus (Mouse),deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264] comp137491_c0_seq1,2702,47.8164,0.55107041,160,238,,0,Q5ZIJ9,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,0,CHOYP_PHUM_PHUM516040.1.1,2.00E-14,ruditapes_c23229,,,,,MIB2_CHICK,Gallus gallus (Chicken),Notch signaling pathway [GO:0007219] comp137492_c0_seq1,2244,39.9733,0.5149289,1129,4184,,4.00E-160,P33610,DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58),DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58),GO:0051539; GO:0003677; GO:0003896; GO:0046872; GO:1990077,"4 iron, 4 sulfur cluster binding; DNA binding; DNA primase activity; metal ion binding; primosome complex",PF04104;,4.00E-82,CHOYP_LOC100378741.1.1,,,,,,,PRI2_MOUSE,Mus musculus (Mouse), comp137495_c0_seq5,987,27.4569,0.37817187,1,17,,,,,,,,,,,2.00E-16,ruditapes_c24551,,,,,,, comp137496_c0_seq1,270,45.9259,0.58994007,19,5,,4.00E-25,Q86YW9,Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like),Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09497;PF12145;PF12144;,,,,,,,,,MD12L_HUMAN,Homo sapiens (Human), comp137496_c1_seq1,1440,50.4861,0.45363198,53,45,,3.00E-17,Q9VW47,Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230),Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230),GO:0001104; GO:0022416; GO:0048749; GO:0036011; GO:0016592; GO:0030177; GO:0045498; GO:0006367,RNA polymerase II transcription cofactor activity; chaeta development; compound eye development; imaginal disc-derived leg segmentation; mediator complex; positive regulation of Wnt receptor signaling pathway; sex comb development; transcription initiation from RNA polymerase II promoter,PF09497;PF12145;,5.00E-16,CHOYP_MD12L.1.1,,,,,,,MED12_DROME,Drosophila melanogaster (Fruit fly),chaeta development [GO:0022416]; compound eye development [GO:0048749]; ecdysone-mediated induction of salivary gland cell autophagic cell death [GO:0035072]; imaginal disc-derived leg segmentation [GO:0036011]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sex comb development [GO:0045498]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp137498_c0_seq1,1389,38.7329,0.62467556,763,2664,,,,,,,,,1.00E-130,CHOYP_BRAFLDRAFT_114843.2.2,2.00E-17,ruditapes_c2155,,,,,,, comp137498_c0_seq2,1406,38.478,0.6255074,405,953,,5.00E-112,Q7TP17,Splicing factor U2AF 26 kDa subunit (Liver regeneration-related protein LRRG157/LRRG158) (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4),Splicing factor U2AF 26 kDa subunit (Liver regeneration-related protein LRRG157/LRRG158) (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4),GO:0003723; GO:0008380; GO:0006397; GO:0046872; GO:0016607; GO:0000166; GO:0005681,RNA binding; RNA splicing; mRNA processing; metal ion binding; nuclear speck; nucleotide binding; spliceosomal complex,PF00076;PF00642;,9.00E-139,CHOYP_BRAFLDRAFT_202693.1.4,3.00E-124,ruditapes2_c839,,,,,U2AF4_RAT,Rattus norvegicus (Rat),"mRNA splicing, via spliceosome [GO:0000398]" comp137499_c0_seq1,2148,43.1099,1.05291547,17,0,,5.00E-13,P22612,cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11),cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11),GO:0005524; GO:0007202; GO:0034199; GO:0007596; GO:0004691; GO:0071377; GO:0005829; GO:0006112; GO:0007173; GO:0008543; GO:0006094; GO:0045087; GO:0007243; GO:0008584; GO:0048011; GO:0050796; GO:0044281; GO:0007283; GO:0055085; GO:0019433; GO:0006833,ATP binding; activation of phospholipase C activity; activation of protein kinase A activity; blood coagulation; cAMP-dependent protein kinase activity; cellular response to glucagon stimulus; cytosol; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; gluconeogenesis; innate immune response; intracellular protein kinase cascade; male gonad development; neurotrophin TRK receptor signaling pathway; regulation of insulin secretion; small molecule metabolic process; spermatogenesis; transmembrane transport; triglyceride catabolic process; water transport,PF00069;,,,,,,,,,KAPCG_HUMAN,Homo sapiens (Human),activation of protein kinase A activity [GO:0034199]; blood coagulation [GO:0007596]; cellular response to glucagon stimulus [GO:0071377]; lipoprotein metabolic process [GO:0042157]; male gonad development [GO:0008584]; renal water homeostasis [GO:0003091]; spermatogenesis [GO:0007283]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] comp137500_c3_seq1,1677,42.9934,1.0669007,145,639,,9.00E-91,Q92485,Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),GO:0005615; GO:0016798; GO:0006685; GO:0004767,"extracellular space; hydrolase activity, acting on glycosyl bonds; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity",PF00149;,4.00E-11,CHOYP_LOC564392.1.1,,,,,,,ASM3B_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] comp137502_c1_seq1,1930,44.1969,0.31878723,0,11,,2.00E-168,Q9JJ66,Cell division cycle protein 20 homolog (mmCdc20) (p55CDC),Cell division cycle protein 20 homolog (mmCdc20) (p55CDC),GO:0051488; GO:0005680; GO:0031145; GO:0030154; GO:0051301; GO:0005737; GO:0005815; GO:0007067; GO:0007399; GO:0090129; GO:0031915; GO:0016567; GO:0040020; GO:0000922,activation of anaphase-promoting complex activity; anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell differentiation; cell division; cytoplasm; microtubule organizing center; mitosis; nervous system development; positive regulation of synapse maturation; positive regulation of synaptic plasticity; protein ubiquitination; regulation of meiosis; spindle pole,PF12894;PF00400;,,,,,,,,,CDC20_MOUSE,Mus musculus (Mouse),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020] comp137502_c1_seq2,1986,44.1088,0.35229954,1,31,,1.00E-10,Q8R537,Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),GO:0008611; GO:0005777; GO:0005053; GO:0016558,ether lipid biosynthetic process; peroxisome; peroxisome matrix targeting signal-2 binding; protein import into peroxisome matrix,PF00400;,,,,,,,,,PEX7_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),ether lipid biosynthetic process [GO:0008611]; protein import into peroxisome matrix [GO:0016558] comp137502_c1_seq3,1762,44.4949,0.33314448,0,24,,6.00E-124,Q54MZ3,Anaphase-promoting complex subunit cdc20,Anaphase-promoting complex subunit cdc20,GO:0051301; GO:0007067; GO:0005634; GO:0045335; GO:0016567,cell division; mitosis; nucleus; phagocytic vesicle; protein ubiquitination,PF12894;PF00400;,,,,,,,,,CDC20_DICDI,Dictyostelium discoideum (Slime mold),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp137502_c1_seq4,1086,42.3573,0.29084193,0,11,,3.00E-69,Q54KM3,Anaphase-promoting complex subunit cdh1,Anaphase-promoting complex subunit cdh1,GO:0051301; GO:0007067; GO:0005634; GO:0016567,cell division; mitosis; nucleus; protein ubiquitination,PF12894;PF00400;,6.00E-64,CHOYP_LOC100378644.1.2,,,,,,,CDH1_DICDI,Dictyostelium discoideum (Slime mold),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp137502_c1_seq5,1287,43.0458,0.25439478,0,10,,2.00E-137,Q9JJ66,Cell division cycle protein 20 homolog (mmCdc20) (p55CDC),Cell division cycle protein 20 homolog (mmCdc20) (p55CDC),GO:0051488; GO:0005680; GO:0031145; GO:0030154; GO:0051301; GO:0005737; GO:0005815; GO:0007067; GO:0007399; GO:0090129; GO:0031915; GO:0016567; GO:0040020; GO:0000922,activation of anaphase-promoting complex activity; anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell differentiation; cell division; cytoplasm; microtubule organizing center; mitosis; nervous system development; positive regulation of synapse maturation; positive regulation of synaptic plasticity; protein ubiquitination; regulation of meiosis; spindle pole,PF12894;PF00400;,6.00E-71,CHOYP_LOC100378644.2.2,,,,,,,CDC20_MOUSE,Mus musculus (Mouse),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020] comp137506_c1_seq1,1709,40.1989,0.40469484,58,265,,8.00E-175,P53590,"Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) (Fragment)","Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) (Fragment)",GO:0005524; GO:0005525; GO:0005739; GO:0004776; GO:0006099,ATP binding; GTP binding; mitochondrion; succinate-CoA ligase (GDP-forming) activity; tricarboxylic acid cycle,PF08442;PF00549;,5.00E-93,CHOYP_SUCB2.1.1,,,,,,,SUCB2_PIG,Sus scrofa (Pig),tricarboxylic acid cycle [GO:0006099] comp137508_c1_seq1,1151,31.8853,0.44550248,65,346,,,,,,,,,,,2.00E-18,ruditapes_c26003,,,,,,, comp137513_c0_seq1,2009,34.7437,0.32376213,17,139,,5.00E-101,Q5ZHV5,JmjC domain-containing protein 4 (Jumonji domain-containing protein 4),JmjC domain-containing protein 4 (Jumonji domain-containing protein 4),,,,,,,,,,,,JMJD4_CHICK,Gallus gallus (Chicken), comp137513_c0_seq2,1403,38.2038,0.26898547,0,13,,2.00E-103,Q5ZHV5,JmjC domain-containing protein 4 (Jumonji domain-containing protein 4),JmjC domain-containing protein 4 (Jumonji domain-containing protein 4),,,,9.00E-82,CHOYP_LOC753089.1.1,,,,,,,JMJD4_CHICK,Gallus gallus (Chicken), comp137513_c0_seq3,358,41.0615,0.26942049,0,44,,1.00E-06,Q9VD28,Bifunctional arginine demethylase and lysyl-hydroxylase PSR (EC 1.14.11.-),Bifunctional arginine demethylase and lysyl-hydroxylase PSR (EC 1.14.11.-),GO:0035212; GO:0016568; GO:0046872; GO:0046329; GO:0043066; GO:0005634; GO:0070815; GO:0018395; GO:0006355; GO:0006351,"cell competition in a multicellular organism; chromatin modification; metal ion binding; negative regulation of JNK cascade; negative regulation of apoptotic process; nucleus; peptidyl-lysine 5-dioxygenase activity; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02373;,,,,,,,,,JMJD6_DROME,Drosophila melanogaster (Fruit fly),"cell competition in a multicellular organism [GO:0035212]; chromatin modification [GO:0016568]; negative regulation of apoptotic process [GO:0043066]; negative regulation of JNK cascade [GO:0046329]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137514_c1_seq2,1883,39.8832,0.40256422,0,0,,1.00E-177,Q8K1R3,"Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)","Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)",GO:0000175; GO:0035458; GO:0034599; GO:0035198; GO:0000965; GO:0000964; GO:0045025; GO:0005758; GO:0000958; GO:0097222; GO:0070584; GO:0071850; GO:0045926; GO:0071042; GO:0005886; GO:0034046; GO:0008266; GO:0004654; GO:0061014; GO:2000627; GO:0000962; GO:0070207; GO:0035928; GO:0043457; GO:2000772,3'-5'-exoribonuclease activity; cellular response to interferon-beta; cellular response to oxidative stress; miRNA binding; mitochondrial RNA 3'-end processing; mitochondrial RNA 5'-end processing; mitochondrial degradosome; mitochondrial intermembrane space; mitochondrial mRNA catabolic process; mitochondrial mRNA polyadenylation; mitochondrion morphogenesis; mitotic cell cycle arrest; negative regulation of growth; nuclear polyadenylation-dependent mRNA catabolic process; plasma membrane; poly(G) RNA binding; poly(U) RNA binding; polyribonucleotide nucleotidyltransferase activity; positive regulation of mRNA catabolic process; positive regulation of miRNA catabolic process; positive regulation of mitochondrial RNA catabolic process; protein homotrimerization; rRNA import into mitochondrion; regulation of cellular respiration; regulation of cellular senescence,PF00013;PF03726;PF01138;PF03725;PF00575;,,,,,,,,,PNPT1_MOUSE,Mus musculus (Mouse),cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mitotic cell cycle arrest [GO:0071850]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928] comp137514_c1_seq4,1804,39.6896,0.42457614,0,0,,1.00E-70,Q5GTR3,Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase),Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase),GO:0000175; GO:0003723; GO:0006396; GO:0005737; GO:0006402; GO:0000287; GO:0004654,3'-5'-exoribonuclease activity; RNA binding; RNA processing; cytoplasm; mRNA catabolic process; magnesium ion binding; polyribonucleotide nucleotidyltransferase activity,PF00013;PF03726;PF01138;PF03725;PF00575;,8.00E-46,CHOYP_PNPT1.1.1,,,,,,,PNP_WOLTR,Wolbachia sp. subsp. Brugia malayi (strain TRS),mRNA catabolic process [GO:0006402]; RNA processing [GO:0006396] comp137516_c0_seq1,706,43.6261,0.80656772,3430,19393,,2.00E-107,Q01105,Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I),Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I),GO:0003677; GO:0006260; GO:0005829; GO:0005783; GO:0010467; GO:0042393; GO:0016071; GO:0035067; GO:0043524; GO:0045892; GO:0006913; GO:0005654; GO:0006334; GO:0006337; GO:0048471; GO:0043234; GO:0004864; GO:0008601,"DNA binding; DNA replication; cytosol; endoplasmic reticulum; gene expression; histone binding; mRNA metabolic process; negative regulation of histone acetylation; negative regulation of neuron apoptotic process; negative regulation of transcription, DNA-dependent; nucleocytoplasmic transport; nucleoplasm; nucleosome assembly; nucleosome disassembly; perinuclear region of cytoplasm; protein complex; protein phosphatase inhibitor activity; protein phosphatase type 2A regulator activity",PF00956;,1.00E-152,CHOYP_GBLP.7.7,1.00E-157,ruditapes_c1784,,,,,SET_HUMAN,Homo sapiens (Human),"DNA replication [GO:0006260]; negative regulation of histone acetylation [GO:0035067]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleocytoplasmic transport [GO:0006913]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; regulation of mRNA stability [GO:0043488]; viral process [GO:0016032]" comp137516_c1_seq1,1029,36.8319,0.75891613,9036,46112,,,,,,,,,,,4.00E-32,ruditapes_lrc32438,,,,,,, comp137517_c0_seq1,1926,41.433,0.93967284,207,906,,,,,,,,,5.00E-17,CHOYP_IRF1.3.3,,,,,,,,, comp137517_c0_seq3,1110,45.9459,0.83938331,0,0,,2.00E-37,Q98925,Interferon regulatory factor 2 (IRF-2),Interferon regulatory factor 2 (IRF-2),GO:0005925; GO:0005634; GO:0000975; GO:0003700; GO:0006351,"focal adhesion; nucleus; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00605;,3.00E-17,CHOYP_IRF1.3.3,,,,,,,IRF2_CHICK,Gallus gallus (Chicken),cell proliferation [GO:0008283] comp137518_c0_seq1,2592,32.7546,0.59652685,13819,54619,,5.00E-121,P38542,GTP-binding nuclear protein Ran (GTPase Ran) (Ras-like protein TC4),GTP-binding nuclear protein Ran (GTPase Ran) (Ras-like protein TC4),GO:0005525; GO:0003924; GO:0006886; GO:0006913; GO:0005634; GO:0007264,GTP binding; GTPase activity; intracellular protein transport; nucleocytoplasmic transport; nucleus; small GTPase mediated signal transduction,PF00071;,2.00E-145,CHOYP_RAN.2.3,6.00E-161,ruditapes_c13383,,,,,RAN_BRUMA,Brugia malayi (Filarial nematode worm),intracellular protein transport [GO:0006886]; nucleocytoplasmic transport [GO:0006913]; small GTPase mediated signal transduction [GO:0007264] comp137519_c0_seq1,252,43.6508,0.16727536,4,8,,3.00E-07,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,1.00E-11,ruditapes_c18515,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp137521_c0_seq2,1953,41.9355,0.50910713,66,251,,0,P97275,"Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)","Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)",GO:0071949; GO:0008762; GO:0008609; GO:0008611; GO:0005778,FAD binding; UDP-N-acetylmuramate dehydrogenase activity; alkylglycerone-phosphate synthase activity; ether lipid biosynthetic process; peroxisomal membrane,PF02913;PF01565;,0,CHOYP_AGPS.1.1,,,,,,,ADAS_CAVPO,Cavia porcellus (Guinea pig),ether lipid biosynthetic process [GO:0008611] comp137522_c0_seq4,681,47.1366,0.39731327,48,95,,4.00E-40,Q6E2N3,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;,1.00E-12,CHOYP_TRIM33.1.1,,,,,,,TRI33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp137522_c1_seq1,335,37.3134,0.86154614,11,4,,1.00E-22,Q13263,Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (Tripartite motif-containing protein 28),Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (Tripartite motif-containing protein 28),GO:0003677; GO:0006281; GO:0035851; GO:0060028; GO:0060669; GO:0001837; GO:0000122; GO:0045892; GO:0005719; GO:0005720; GO:0005654; GO:0045739; GO:0042993; GO:0045893; GO:0046777; GO:0004672; GO:0051259; GO:0016925; GO:0043565; GO:0003700; GO:0003713; GO:0003714; GO:0006367; GO:0031625; GO:0004842; GO:0008270,"DNA binding; DNA repair; Krueppel-associated box domain binding; convergent extension involved in axis elongation; embryonic placenta morphogenesis; epithelial to mesenchymal transition; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nuclear euchromatin; nuclear heterochromatin; nucleoplasm; positive regulation of DNA repair; positive regulation of transcription factor import into nucleus; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein kinase activity; protein oligomerization; protein sumoylation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; transcription initiation from RNA polymerase II promoter; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; zinc ion binding",PF00628;PF00643;PF14634;,,,,,,,,,TIF1B_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; convergent extension involved in axis elongation [GO:0060028]; DNA methylation involved in embryo development [GO:0043045]; DNA repair [GO:0006281]; embryo implantation [GO:0007566]; embryonic placenta morphogenesis [GO:0060669]; epithelial to mesenchymal transition [GO:0001837]; innate immune response [GO:0045087]; negative regulation of DNA demethylation [GO:1901536]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral release from host cell [GO:1902187]; positive regulation of DNA repair [GO:0045739]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription factor import into nucleus [GO:0042993]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein sumoylation [GO:0016925]; Ras protein signal transduction [GO:0007265]; regulation of genetic imprinting [GO:2000653]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp137524_c0_seq2,1783,44.1391,0.49767759,157,45,,0,P59114,Phosphorylated CTD-interacting factor 1,Phosphorylated CTD-interacting factor 1,GO:0015629; GO:0005825; GO:0010923; GO:0005634,actin cytoskeleton; half bridge of spindle pole body; negative regulation of phosphatase activity; nucleus,PF12237;PF00397;,1.00E-131,CHOYP_PCIF1.1.1,,,,,,,PCIF1_MOUSE,Mus musculus (Mouse),negative regulation of phosphatase activity [GO:0010923] comp137528_c0_seq1,1475,41.0169,0.99471951,2374,0,,9.00E-78,Q9D411,Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1),Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1),GO:0005524; GO:0001669; GO:0030154; GO:0000287; GO:0031514; GO:0007275; GO:0032793; GO:0004674; GO:0007283,ATP binding; acrosomal vesicle; cell differentiation; magnesium ion binding; motile cilium; multicellular organismal development; positive regulation of CREB transcription factor activity; protein serine/threonine kinase activity; spermatogenesis,PF00069;,4.00E-29,CHOYP_LOC100377552.1.1,,,,,,,TSSK4_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] comp137532_c0_seq1,1196,34.6154,0.87588873,958,2873,,4.00E-89,P83877,Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD),Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD),GO:0008380; GO:0051301; GO:0006397; GO:0007067; GO:0005681,RNA splicing; cell division; mRNA processing; mitosis; spliceosomal complex,PF02966;,4.00E-104,CHOYP_TXN4A.1.2,2.00E-105,ruditapes_c19811,,,,,TXN4A_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spliceosomal complex assembly [GO:0000245] comp137533_c0_seq1,1466,45.2933,0.46653967,379,1115,,3.00E-41,Q68CZ6,HAUS augmin-like complex subunit 3,HAUS augmin-like complex subunit 3,GO:0070652; GO:0051301; GO:0005813; GO:0051297; GO:0005737; GO:0005874; GO:0007067; GO:0005819; GO:0051225,HAUS complex; cell division; centrosome; centrosome organization; cytoplasm; microtubule; mitosis; spindle; spindle assembly,PF14932;,,,,,,,,,HAUS3_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp137536_c0_seq1,1299,44.6497,0.60331322,0,0,,5.00E-32,Q5ZLC6,Ankyrin repeat domain-containing protein 10,Ankyrin repeat domain-containing protein 10,,,PF12796;,,,,,,,,,ANR10_CHICK,Gallus gallus (Chicken),regulation of canonical Wnt signaling pathway [GO:0060828] comp137536_c0_seq3,1434,45.1883,0.66987753,0,0,,3.00E-16,Q812A3,Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein),Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein),GO:0031674; GO:0015629; GO:0006631; GO:0005634,I band; actin cytoskeleton; fatty acid metabolic process; nucleus,PF00023;PF12796;,2.00E-15,CHOYP_ANKRD10.2.2,,,,,,,ANR23_MOUSE,Mus musculus (Mouse),fatty acid metabolic process [GO:0006631]; regulation of sarcomere organization [GO:0060297]; response to muscle stretch [GO:0035994] comp137536_c0_seq4,1561,41.2556,0.51280884,0,0,,4.00E-54,Q5ZLC6,Ankyrin repeat domain-containing protein 10,Ankyrin repeat domain-containing protein 10,,,PF12796;,2.00E-15,CHOYP_ANKRD10.2.2,,,,,,,ANR10_CHICK,Gallus gallus (Chicken),regulation of canonical Wnt signaling pathway [GO:0060828] comp137536_c0_seq6,1426,40.3927,0.41308459,0,0,,6.00E-25,Q28FJ2,Ankyrin repeat domain-containing protein 37,Ankyrin repeat domain-containing protein 37,,,PF12796;,,,,,,,,,ANR37_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp137536_c1_seq1,818,45.11,0.60185275,7,2,,1.00E-30,Q9QZN1,F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13),F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13),,,PF12937;PF13516;,,,,,,,,,FXL17_MOUSE,Mus musculus (Mouse), comp137539_c0_seq1,2202,41.9619,0.55640868,105,77,,2.00E-104,Q1LY77,Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.43) (SET domain-containing protein 1B-A),Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.43) (SET domain-containing protein 1B-A),GO:0003723; GO:0005694; GO:0034968; GO:0018024; GO:0016607; GO:0000166; GO:0006355; GO:0006351,"RNA binding; chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nuclear speck; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11764;PF00076;PF00856;,1.00E-75,CHOYP_LOC657811.1.1,,,,,,,SE1BA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137539_c1_seq1,2971,43.8909,0.46449052,117,100,,6.00E-39,Q1LY77,Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.43) (SET domain-containing protein 1B-A),Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.43) (SET domain-containing protein 1B-A),GO:0003723; GO:0005694; GO:0034968; GO:0018024; GO:0016607; GO:0000166; GO:0006355; GO:0006351,"RNA binding; chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nuclear speck; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11764;PF00076;PF00856;,3.00E-47,CHOYP_LOC657811.1.1,,,,,,,SE1BA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137540_c0_seq3,2693,43.446,0.49464677,10,10,,2.00E-14,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137540_c0_seq4,2672,44.0868,0.51630385,10,3,,2.00E-14,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137542_c0_seq1,2436,40.8867,0.92405947,99,1995,,1.00E-96,Q08890,Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase),Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase),GO:0004423; GO:0005764; GO:0046872; GO:0008484,iduronate-2-sulfatase activity; lysosome; metal ion binding; sulfuric ester hydrolase activity,PF00884;,,,5.00E-16,ruditapes_c7114,,,,,IDS_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp137543_c2_seq1,502,50.5976,0.79944312,84,37,,1.00E-25,Q5RBR8,Eukaryotic translation initiation factor 4H (eIF-4H),Eukaryotic translation initiation factor 4H (eIF-4H),GO:0000166; GO:0048471; GO:0003743,nucleotide binding; perinuclear region of cytoplasm; translation initiation factor activity,PF00076;,1.00E-42,CHOYP_EIF4H.1.3,,,,,,,IF4H_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp137545_c0_seq2,1571,38.9561,0.46157378,7,32,,7.00E-34,A1A5P9,Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (MAGE-E1 antigen),Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (MAGE-E1 antigen),GO:0030425; GO:0016010; GO:0005634; GO:0048471; GO:0045211,dendrite; dystrophin-associated glycoprotein complex; nucleus; perinuclear region of cytoplasm; postsynaptic membrane,PF01454;,,,,,,,,,MAGE1_RAT,Rattus norvegicus (Rat), comp137545_c0_seq5,1522,39.0933,0.50893044,1,81,,1.00E-54,Q96MG7,Melanoma-associated antigen G1 (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Necdin-like protein 2),Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2),GO:0006310; GO:0006281; GO:0030915; GO:0000781; GO:0005737; GO:0005634; GO:0031398; GO:0040008; GO:0006355,"DNA recombination; DNA repair; Smc5-Smc6 complex; chromosome, telomeric region; cytoplasm; nucleus; positive regulation of protein ubiquitination; regulation of growth; regulation of transcription, DNA-dependent",PF01454;,,,,,,,,,MAGG1_HUMAN,Homo sapiens (Human),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of protein ubiquitination [GO:0031398]; protein sumoylation [GO:0016925]; regulation of growth [GO:0040008] comp137549_c0_seq1,2870,39.2334,0.77692595,542,1155,,0,O15975,Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q),Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q),GO:0007186; GO:0005525; GO:0003924; GO:0046872; GO:0004871,G-protein coupled receptor signaling pathway; GTP binding; GTPase activity; metal ion binding; signal transducer activity,PF00503;,0,CHOYP_GNAQ.1.1,2.00E-23,ruditapes_lrc18028,,,,,GNAQ_MIZYE,Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis),G-protein coupled receptor signaling pathway [GO:0007186] comp137551_c1_seq1,2595,38.6127,0.57926811,76,557,,4.00E-20,O00472,RNA polymerase II elongation factor ELL2,RNA polymerase II elongation factor ELL2,GO:0006355; GO:0008023; GO:0006368,"regulation of transcription, DNA-dependent; transcription elongation factor complex; transcription elongation from RNA polymerase II promoter",PF10390;PF07303;,,,,,,,,,ELL2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp137551_c1_seq3,1582,34.7029,0.52845604,0,7,,1.00E-11,O08856,RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein),RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein),GO:0015030; GO:0001701; GO:0010923; GO:0016607; GO:0019902; GO:0006355; GO:0008023; GO:0006368,"Cajal body; in utero embryonic development; negative regulation of phosphatase activity; nuclear speck; phosphatase binding; regulation of transcription, DNA-dependent; transcription elongation factor complex; transcription elongation from RNA polymerase II promoter",PF10390;PF07303;,,,,,,,,,ELL_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; snRNA transcription from RNA polymerase III promoter [GO:0042796]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp137552_c0_seq1,1764,43.7075,0.56156556,0,0,,,,,,,,,3.00E-25,CHOYP_LOC100876515.1.2,,,,,,,,, comp137552_c0_seq3,2187,43.1184,0.54362261,40,16,,4.00E-77,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp137552_c0_seq4,1143,42.8696,0.59983267,2,0,,,,,,,,,,,2.00E-48,ruditapes_c10549,,,,,,, comp137552_c0_seq5,681,42.5844,0.48992012,56,25,,1.00E-18,Q96JQ2,Calmin (Calponin-like transmembrane domain protein),Calmin (Calponin-like transmembrane domain protein),GO:0005737; GO:0016021; GO:0008285; GO:0031175,cytoplasm; integral to membrane; negative regulation of cell proliferation; neuron projection development,PF00307;,2.00E-60,CHOYP_LOC100876515.1.2,,,,,,,CLMN_HUMAN,Homo sapiens (Human),negative regulation of cell proliferation [GO:0008285]; neuron projection development [GO:0031175] comp137553_c0_seq1,1808,35.5088,0.44481287,99,365,,,,,,,,,4.00E-18,CHOYP_BRAFLDRAFT_98499.1.1,,,,,,,,, comp137557_c0_seq1,2103,38.3262,0.3911145,130,305,,3.00E-136,O73787,Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p),Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p),GO:0005737; GO:0005874; GO:0007020; GO:0005815; GO:0000922,cytoplasm; microtubule; microtubule nucleation; microtubule organizing center; spindle pole,PF04130;,1.00E-113,CHOYP_BRAFLDRAFT_278559.1.1,,,,,,,GCP3_XENLA,Xenopus laevis (African clawed frog),microtubule nucleation [GO:0007020] comp137560_c0_seq1,774,41.3437,0.37164384,3,13,,2.00E-96,P40692,DNA mismatch repair protein Mlh1 (MutL protein homolog 1),DNA mismatch repair protein Mlh1 (MutL protein homolog 1),GO:0005524; GO:0016887; GO:0032389; GO:0032390; GO:0005712; GO:0006303; GO:0032137; GO:0008630; GO:0045190; GO:0001673; GO:0007060; GO:0043060; GO:0006298; GO:0045950; GO:0000289; GO:0048477; GO:0007131; GO:0000712; GO:0016446; GO:0007283; GO:0051257; GO:0007129; GO:0000795,ATP binding; ATPase activity; MutLalpha complex; MutLbeta complex; chiasma; double-strand break repair via nonhomologous end joining; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; male germ cell nucleus; male meiosis chromosome segregation; meiotic metaphase I plate congression; mismatch repair; negative regulation of mitotic recombination; nuclear-transcribed mRNA poly(A) tail shortening; oogenesis; reciprocal meiotic recombination; resolution of meiotic recombination intermediates; somatic hypermutation of immunoglobulin genes; spermatogenesis; spindle midzone assembly involved in meiosis; synapsis; synaptonemal complex,PF01119;PF16413;,8.00E-99,CHOYP_MLH1.1.1,,,,,,,MLH1_HUMAN,Homo sapiens (Human),double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp137560_c0_seq2,670,40.1493,0.52539267,8,33,,4.00E-11,Q13401,Putative postmeiotic segregation increased 2-like protein 3 (PMS2-related protein 3) (Postmeiotic segregation increased 2-like protein 9) (Postmeiotic segregation increased protein 5) (Putative postmeiotic segregation increased 2 pseudogene 3),Putative postmeiotic segregation increased 2-like protein 3 (PMS2-related protein 3) (Postmeiotic segregation increased 2-like protein 9) (Postmeiotic segregation increased protein 5) (Putative postmeiotic segregation increased 2 pseudogene 3),GO:0005524; GO:0005622; GO:0006298; GO:0030983; GO:0006355,"ATP binding; intracellular; mismatch repair; mismatched DNA binding; regulation of transcription, DNA-dependent",PF01352;,,,,,,,,,PM2P3_HUMAN,Homo sapiens (Human),"mismatch repair [GO:0006298]; regulation of transcription, DNA-templated [GO:0006355]" comp137568_c0_seq3,232,39.2241,0.45287528,4,11,,2.00E-07,P04025,Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)],Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0075713; GO:0090305; GO:0004523; GO:0046718; GO:0008270,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; viral entry into host cell; zinc ion binding,PF00552;PF02022;PF00075;PF00665;PF00078;PF06817;,,,,,,,,,POL_SRV1,Simian retrovirus SRV-1,DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp137570_c3_seq2,786,34.6056,0.55907194,3,0,,8.00E-08,Q640I9,Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B),Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B),GO:0003677; GO:0070544; GO:0051864; GO:0005730; GO:0019843; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); nucleolus; rRNA binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00646;PF02373;PF16866;PF02008;,,,,,,,,,KDM2B_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137570_c3_seq3,635,36.378,0.62034968,0,0,,5.00E-07,Q3T0G1,THAP domain-containing protein 1,THAP domain-containing protein 1,GO:0016605; GO:0007049; GO:0001935; GO:0005634; GO:0007346; GO:0006355; GO:0043565; GO:0006351; GO:0008270,"PML body; cell cycle; endothelial cell proliferation; nucleus; regulation of mitotic cell cycle; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; zinc ion binding",PF05485;,,,,,,,,,THAP1_BOVIN,Bos taurus (Bovine),"cell cycle [GO:0007049]; endothelial cell proliferation [GO:0001935]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137570_c3_seq4,1169,40.2908,0.32148769,3,0,,2.00E-07,Q8CE22,Cyclin-D-binding Myb-like transcription factor 1 (Cyclin-D-interacting Myb-like protein 1) (mDmp1),Cyclin-D-binding Myb-like transcription factor 1 (Cyclin-D-interacting Myb-like protein 1) (mDmp1),GO:0003677; GO:0007049; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell cycle; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00249;,,,,,,,,,DMTF1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137570_c3_seq6,714,36.5546,0.54618746,0,2,,8.00E-07,Q3T0G1,THAP domain-containing protein 1,THAP domain-containing protein 1,GO:0016605; GO:0007049; GO:0001935; GO:0005634; GO:0007346; GO:0006355; GO:0043565; GO:0006351; GO:0008270,"PML body; cell cycle; endothelial cell proliferation; nucleus; regulation of mitotic cell cycle; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; zinc ion binding",PF05485;,,,,,,,,,THAP1_BOVIN,Bos taurus (Bovine),"cell cycle [GO:0007049]; endothelial cell proliferation [GO:0001935]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137570_c3_seq7,2875,38.3304,0.41747581,2,15,,8.00E-08,Q9VHH9,JmjC domain-containing histone demethylation protein 1 (EC 1.14.11.27) (Lysine (K)-specific demethylase 2) ([Histone-H3]-lysine-36 demethylase 1),JmjC domain-containing histone demethylation protein 1 (EC 1.14.11.27) (Lysine (K)-specific demethylase 2) ([Histone-H3]-lysine-36 demethylase 1),GO:0003677; GO:0031519; GO:0033522; GO:0070544; GO:0051864; GO:0034647; GO:0006355; GO:0007379; GO:0006351; GO:0008270,"DNA binding; PcG protein complex; histone H2A ubiquitination; histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-trimethyl-K4 specific); regulation of transcription, DNA-dependent; segment specification; transcription, DNA-dependent; zinc ion binding",PF12937;PF13516;PF16866;PF02008;,,,,,,,,,JHD1_DROME,Drosophila melanogaster (Fruit fly),"histone H2A ubiquitination [GO:0033522]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation, trimethyl-H3-K4-specific [GO:0034721]; larval somatic muscle development [GO:0007526]; regulation of transcription, DNA-templated [GO:0006355]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]" comp137570_c3_seq8,2887,38.3789,0.4147435,0,3,,9.00E-07,Q8NHM5,Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B),Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B),GO:0003677; GO:0048596; GO:0021592; GO:0035518; GO:0070544; GO:0032452; GO:0051864; GO:0021993; GO:0021670; GO:0030901; GO:0021555; GO:2000178; GO:0043524; GO:0000122; GO:0005730; GO:0005634; GO:0019843; GO:0007283; GO:0021678; GO:0006351; GO:0008270,"DNA binding; embryonic camera-type eye morphogenesis; fourth ventricle development; histone H2A monoubiquitination; histone H3-K36 demethylation; histone demethylase activity; histone demethylase activity (H3-K36 specific); initiation of neural tube closure; lateral ventricle development; midbrain development; midbrain-hindbrain boundary morphogenesis; negative regulation of neural precursor cell proliferation; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; rRNA binding; spermatogenesis; third ventricle development; transcription, DNA-dependent; zinc ion binding",PF00646;PF16866;PF02008;,,,,,,,,,KDM2B_HUMAN,Homo sapiens (Human),"embryonic camera-type eye morphogenesis [GO:0048596]; forebrain development [GO:0030900]; fourth ventricle development [GO:0021592]; hindbrain development [GO:0030902]; histone H2A monoubiquitination [GO:0035518]; initiation of neural tube closure [GO:0021993]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of stem cell population maintenance [GO:1902459]; spermatogenesis [GO:0007283]; third ventricle development [GO:0021678]; transcription, DNA-templated [GO:0006351]" comp137570_c5_seq1,307,37.1336,0.76214851,0,19,,,,,,,,,,,5.00E-12,ruditapes_c29520,,,,,,, comp137572_c3_seq3,2772,32.9004,0.61820534,0,0,,4.00E-21,Q99L04,Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),GO:0005783; GO:0005743; GO:0016491,endoplasmic reticulum; mitochondrial inner membrane; oxidoreductase activity,PF00106;,,,,,,,,,DHRS1_MOUSE,Mus musculus (Mouse), comp137572_c3_seq5,2765,32.6582,0.61604791,0,0,,,,,,,,,,,4.00E-12,ruditapes_c12814,,,,,,, comp137572_c3_seq9,678,42.3304,1.15084996,44,579,,8.00E-82,Q99L04,Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),GO:0005783; GO:0005743; GO:0016491,endoplasmic reticulum; mitochondrial inner membrane; oxidoreductase activity,PF00106;,8.00E-41,CHOYP_BRAFLDRAFT_205095.2.2,,,,,,,DHRS1_MOUSE,Mus musculus (Mouse), comp137573_c0_seq1,1505,41.5282,0.44033268,110,175,,1.00E-40,O94913,Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11),Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11),GO:0031124; GO:0006379; GO:0005849; GO:0000398; GO:0006369,"mRNA 3'-end processing; mRNA cleavage; mRNA cleavage factor complex; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription",PF04818;,4.00E-11,CHOYP_PCF11.1.1,,,,,,,PCF11_HUMAN,Homo sapiens (Human),"mRNA 3'-end processing [GO:0031124]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; termination of RNA polymerase II transcription [GO:0006369]" comp137574_c1_seq3,1258,42.5278,0.49642242,0,0,,4.00E-70,Q64707,"U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1)","U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1)",GO:0003723; GO:0046872; GO:0000166; GO:0005634; GO:0030529,RNA binding; metal ion binding; nucleotide binding; nucleus; ribonucleoprotein complex,PF00076;PF00642;,,,,,,,,,U2AFL_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp137574_c1_seq4,1233,42.4169,0.50045094,0,0,,6.00E-41,Q9SY74,Zinc finger CCCH domain-containing protein 5 (AtC3H5),Zinc finger CCCH domain-containing protein 5 (AtC3H5),GO:0003677; GO:0003723; GO:0046872; GO:0000166; GO:0005634,DNA binding; RNA binding; metal ion binding; nucleotide binding; nucleus,PF00642;,,,,,,,,,C3H5_ARATH,Arabidopsis thaliana (Mouse-ear cress),"mRNA splicing, via spliceosome [GO:0000398]" comp137574_c1_seq7,1234,42.4635,0.48473078,0,0,,2.00E-70,Q64707,"U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1)","U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1)",GO:0003723; GO:0046872; GO:0000166; GO:0005634; GO:0030529,RNA binding; metal ion binding; nucleotide binding; nucleus; ribonucleoprotein complex,PF00076;PF00642;,3.00E-31,CHOYP_ZRSR2.1.1,,,,,,,U2AFL_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp137578_c0_seq1,2459,34.5262,0.59163069,8630,20978,,2.00E-31,Q8VE97,"Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)","Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0016607; GO:0000166,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nuclear speck; nucleotide binding",PF00076;,8.00E-29,CHOYP_RS3A.4.15,1.00E-17,ruditapes_c30948,,,,,SRSF4_MOUSE,Mus musculus (Mouse),"hematopoietic progenitor cell differentiation [GO:0002244]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" comp137585_c0_seq3,3620,39.5028,0.62834145,152,376,,,,,,,,,,,1.00E-25,ruditapes_c10033,,,,,,, comp137585_c1_seq1,567,41.6226,0.78458986,13,39,,,,,,,,,,,4.00E-23,ruditapes_c8951,,,,,,, comp137587_c0_seq1,1129,42.1612,0.56339076,256,1247,,5.00E-139,Q6P8M1,Putative deoxyribonuclease TATDN1 (EC 3.1.21.-),Putative deoxyribonuclease TATDN1 (EC 3.1.21.-),GO:0006309; GO:0005737; GO:0004536; GO:0016888; GO:0046872; GO:0005634,"apoptotic DNA fragmentation; cytoplasm; deoxyribonuclease activity; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleus",PF01026;,1.00E-72,CHOYP_LOC580466.1.2,2.00E-92,ruditapes2_c2064,,,,,TATD1_MOUSE,Mus musculus (Mouse),DNA catabolic process [GO:0006308] comp137588_c0_seq1,2277,38.6473,0.46442172,423,3328,,1.00E-179,Q6Q7J2,Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2),Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2),GO:0005096; GO:0005093; GO:0005737; GO:0016020; GO:0043547; GO:0015031,GTPase activator activity; Rab GDP-dissociation inhibitor activity; cytoplasm; membrane; positive regulation of GTPase activity; protein transport,PF00996;,3.00E-109,CHOYP_LOC100168945.1.1,,,,,,,GDIB_PIG,Sus scrofa (Pig),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp137589_c0_seq4,1564,39.2583,0.61674574,157,363,,1.00E-78,Q8TAD8,Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1),Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1),GO:0007249; GO:0005737; GO:0005634; GO:0035196; GO:0006355,"I-kappaB kinase/NF-kappaB cascade; cytoplasm; nucleus; production of miRNAs involved in gene silencing by miRNA; regulation of transcription, DNA-dependent",PF00498;,,,,,,,,,SNIP1_HUMAN,Homo sapiens (Human),"I-kappaB kinase/NF-kappaB signaling [GO:0007249]; positive regulation of protein targeting to mitochondrion [GO:1903955]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of transcription, DNA-templated [GO:0006355]" comp137590_c0_seq1,1793,39.9331,0.33900237,7,27,,1.00E-06,P29294,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_RABIT,Oryctolagus cuniculus (Rabbit), comp137590_c0_seq4,1508,45.2918,0.35317538,6,38,,9.00E-07,P29294,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_RABIT,Oryctolagus cuniculus (Rabbit), comp137592_c0_seq2,3878,42.3672,0.90958234,0,110,,3.00E-56,Q9YGL3,Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll),Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll),GO:0007275; GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,NR2E1_ORYLA,Oryzias latipes (Japanese rice fish) (Japanese killifish),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp137592_c0_seq3,3868,42.5284,0.91600529,0,0,,4.00E-63,Q9TTF0,Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor),Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,NR2E3_BOVIN,Bos taurus (Bovine),"transcription, DNA-templated [GO:0006351]" comp137592_c0_seq4,3894,42.3729,0.91103209,0,1391,female,4.00E-63,Q9TTF0,Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor),Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,2.00E-42,ruditapes_c21976,,,,,NR2E3_BOVIN,Bos taurus (Bovine),"transcription, DNA-templated [GO:0006351]" comp137603_c0_seq1,1511,42.2237,0.28555253,276,1442,,7.00E-92,P27864,Recombination repair protein 1 (DNA-(apurinic or apyrimidinic site) lyase) (EC 4.2.99.18),Recombination repair protein 1 (DNA-(apurinic or apyrimidinic site) lyase) (EC 4.2.99.18),GO:0008408; GO:0003677; GO:0006281; GO:0003906; GO:0004519; GO:0046872; GO:0005634; GO:0006974,3'-5' exonuclease activity; DNA binding; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; endonuclease activity; metal ion binding; nucleus; response to DNA damage stimulus,PF03372;,2.00E-33,CHOYP_LOC100373457.1.1,,,,,,,RRP1_DROME,Drosophila melanogaster (Fruit fly),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974] comp137603_c0_seq2,1532,42.2324,0.2668873,235,1390,,9.00E-114,A0MTA1,DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (zAP1),DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (zAP1),GO:0003677; GO:0080111; GO:0006281; GO:0003906; GO:0003723; GO:0004519; GO:0005783; GO:0060047; GO:0001947; GO:0046872; GO:0005739; GO:0043066; GO:0016607; GO:0090305; GO:0005730; GO:0010628,DNA binding; DNA demethylation; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; RNA binding; endonuclease activity; endoplasmic reticulum; heart contraction; heart looping; metal ion binding; mitochondrion; negative regulation of apoptotic process; nuclear speck; nucleic acid phosphodiester bond hydrolysis; nucleolus; positive regulation of gene expression,PF03372;,2.00E-33,CHOYP_LOC100373457.1.1,,,,,,,APEX1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; positive regulation of gene expression [GO:0010628] comp137605_c0_seq2,2508,44.4577,0.43037447,154,23,,0,Q99PW8,Kinesin-like protein KIF17 (MmKIF17),Kinesin-like protein KIF17 (MmKIF17),GO:0005524; GO:0036064; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007017; GO:0031503; GO:0015031; GO:0016192,ATP binding; cilium basal body; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; microtubule-based process; protein complex localization; protein transport; vesicle-mediated transport,PF00225;,0,CHOYP_LOC100377381.2.2,,,,,,,KIF17_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neurogenesis [GO:0022008]; protein complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] comp137605_c0_seq3,992,39.3145,0.57465336,41,0,,5.00E-14,P46873,Osmotic avoidance abnormal protein 3 (Kinesin-like protein osm-3),Osmotic avoidance abnormal protein 3 (Kinesin-like protein osm-3),GO:0005524; GO:0036064; GO:0005871; GO:0005874; GO:0007018; GO:0043005; GO:0043025; GO:0031513; GO:0048471; GO:0008574; GO:0046626,ATP binding; cilium basal body; kinesin complex; microtubule; microtubule-based movement; neuron projection; neuronal cell body; nonmotile primary cilium; perinuclear region of cytoplasm; plus-end-directed microtubule motor activity; regulation of insulin receptor signaling pathway,PF00225;,,,,,,,,,OSM3_CAEEL,Caenorhabditis elegans,cell projection organization [GO:0030030]; cilium assembly [GO:0042384]; dauer entry [GO:0043053]; intraciliary anterograde transport [GO:0035720]; neurogenesis [GO:0022008]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of dauer larval development [GO:0061066]; regulation of insulin receptor signaling pathway [GO:0046626] comp137605_c0_seq5,344,37.7907,0.36469653,8,0,,2.00E-14,Q99PW8,Kinesin-like protein KIF17 (MmKIF17),Kinesin-like protein KIF17 (MmKIF17),GO:0005524; GO:0036064; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007017; GO:0031503; GO:0015031; GO:0016192,ATP binding; cilium basal body; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; microtubule-based process; protein complex localization; protein transport; vesicle-mediated transport,PF00225;,2.00E-19,CHOYP_LOC100377381.1.2,,,,,,,KIF17_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neurogenesis [GO:0022008]; protein complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] comp137609_c0_seq1,920,35.9783,0.70898178,41,375,,3.00E-10,P82916,"28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)","28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)",GO:0005739; GO:0019843; GO:0005840; GO:0003735; GO:0006412,mitochondrion; rRNA binding; ribosome; structural constituent of ribosome; translation,PF00366;,,,,,,,,,RT17_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp137609_c0_seq2,934,35.8672,0.66866986,127,574,,3.00E-10,P82916,"28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)","28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)",GO:0005739; GO:0019843; GO:0005840; GO:0003735; GO:0006412,mitochondrion; rRNA binding; ribosome; structural constituent of ribosome; translation,PF00366;,,,,,,,,,RT17_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp137611_c0_seq1,489,42.5358,0.58943524,761,2869,,3.00E-14,Q9CPV3,"39S ribosomal protein L42, mitochondrial (L42mt) (MRP-L42) (28S ribosomal protein S32, mitochondrial) (MRP-S32) (S32mt) (39S ribosomal protein L31, mitochondrial) (L31mt) (MRP-L31)","39S ribosomal protein L42, mitochondrial (L42mt) (MRP-L42) (28S ribosomal protein S32, mitochondrial) (MRP-S32) (S32mt) (39S ribosomal protein L31, mitochondrial) (L31mt) (MRP-L31)",GO:0005763; GO:0005739; GO:0005886,mitochondrial small ribosomal subunit; mitochondrion; plasma membrane,PF10210;,,,,,,,,,RM42_MOUSE,Mus musculus (Mouse), comp137615_c0_seq1,1482,39.2713,0.45871821,0,19,,5.00E-118,Q28DS0,SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A),SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A),GO:0016874; GO:0005634; GO:0008022; GO:0016925; GO:0008641,ligase activity; nucleus; protein C-terminus binding; protein sumoylation; small protein activating enzyme activity,PF00899;,7.00E-52,CHOYP_SAE1.1.1,4.00E-27,ruditapes_c12932,,,,,SAE1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein sumoylation [GO:0016925]; regulation of mitotic cell cycle [GO:0007346] comp137618_c2_seq1,2033,43.6301,0.67311386,0,0,,2.00E-59,Q96MU7,YTH domain-containing protein 1 (Putative splicing factor YT521),YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF04146;,4.00E-75,CHOYP_YTDC1.2.2,,,,,,,YTDC1_HUMAN,Homo sapiens (Human),"mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp137618_c2_seq12,1988,40.3924,0.55665295,0,0,,,,,,,,,4.00E-75,CHOYP_YTDC1.1.2,,,,,,,,, comp137618_c2_seq14,2458,42.3922,0.69292675,0,0,,1.00E-25,B2RR83,Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13),Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;PF01424;PF04146;,5.00E-75,CHOYP_YTDC1.2.2,,,,,,,YTDC2_MOUSE,Mus musculus (Mouse),positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; RNA processing [GO:0006396] comp137618_c2_seq17,1835,39.782,0.51739146,0,0,,8.00E-59,Q96MU7,YTH domain-containing protein 1 (Putative splicing factor YT521),YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF04146;,4.00E-75,CHOYP_YTDC1.2.2,,,,,,,YTDC1_HUMAN,Homo sapiens (Human),"mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp137618_c2_seq24,1672,42.5239,0.60331286,0,0,,7.00E-60,Q96MU7,YTH domain-containing protein 1 (Putative splicing factor YT521),YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF04146;,4.00E-75,CHOYP_YTDC1.2.2,,,,,,,YTDC1_HUMAN,Homo sapiens (Human),"mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp137618_c2_seq5,2443,42.3659,0.69965272,0,0,,1.00E-58,Q96MU7,YTH domain-containing protein 1 (Putative splicing factor YT521),YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF04146;,,,,,,,,,YTDC1_HUMAN,Homo sapiens (Human),"mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp137618_c2_seq7,1717,43.3314,0.62063156,0,0,,,,,,,,,4.00E-75,CHOYP_YTDC1.1.2,,,,,,,,, comp137618_c2_seq8,2048,43.6523,0.66580891,0,0,,2.00E-59,Q96MU7,YTH domain-containing protein 1 (Putative splicing factor YT521),YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF04146;,4.00E-75,CHOYP_YTDC1.2.2,,,,,,,YTDC1_HUMAN,Homo sapiens (Human),"mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp137624_c8_seq1,683,46.1201,0.63961757,39,72,,4.00E-109,Q8HXQ5,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,1.00E-57,CHOYP_MRP1.4.10,,,,,,,MRP1_BOVIN,Bos taurus (Bovine), comp137627_c0_seq1,2489,41.583,0.47133033,3,3,,0,Q60649,Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3),Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3),GO:0005524; GO:0034605; GO:0005739; GO:0017111,ATP binding; cellular response to heat; mitochondrion; nucleoside-triphosphatase activity,PF07724;PF12796;PF10431;,2.00E-157,CHOYP_CLPB.2.3,,,,,,,CLPB_MOUSE,Mus musculus (Mouse),cellular response to heat [GO:0034605] comp137627_c0_seq2,2518,41.4218,0.46943377,7,52,,0,Q60649,Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3),Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3),GO:0005524; GO:0034605; GO:0005739; GO:0017111,ATP binding; cellular response to heat; mitochondrion; nucleoside-triphosphatase activity,PF07724;PF12796;PF10431;,2.00E-157,CHOYP_CLPB.2.3,,,,,,,CLPB_MOUSE,Mus musculus (Mouse),cellular response to heat [GO:0034605] comp137630_c0_seq2,1251,41.5667,0.3709632,0,0,,1.00E-24,Q69ZB8,Zinc finger CCHC domain-containing protein 2,Zinc finger CCHC domain-containing protein 2,GO:0007154; GO:0005737; GO:0003676; GO:0035091; GO:0008270,cell communication; cytoplasm; nucleic acid binding; phosphatidylinositol binding; zinc ion binding,PF00098;,,,,,,,,,ZCHC2_MOUSE,Mus musculus (Mouse), comp137630_c0_seq8,604,43.0464,0.25096365,0,0,,5.00E-06,Q5TCZ1,SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains),SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains),GO:0007154; GO:0030054; GO:0042995; GO:0005737; GO:0035091; GO:0002102; GO:0006801,cell communication; cell junction; cell projection; cytoplasm; phosphatidylinositol binding; podosome; superoxide metabolic process,PF00787;PF00018;,,,,,,,,,SPD2A_HUMAN,Homo sapiens (Human),osteoclast fusion [GO:0072675]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; superoxide metabolic process [GO:0006801] comp137633_c0_seq2,1382,35.9624,0.65695366,474,2085,,9.00E-13,P53563,Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X),Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X),GO:0005813; GO:0043027; GO:0000910; GO:0016021; GO:0005741; GO:0007093; GO:0043066; GO:0031965; GO:0001541; GO:0042542; GO:0001666; GO:0002931; GO:0010288; GO:0014070; GO:0043434,centrosome; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytokinesis; integral to membrane; mitochondrial outer membrane; mitotic cell cycle checkpoint; negative regulation of apoptotic process; nuclear membrane; ovarian follicle development; response to hydrogen peroxide; response to hypoxia; response to ischemia; response to lead ion; response to organic cyclic compound; response to peptide hormone stimulus,PF00452;PF02180;,6.00E-40,CHOYP_ISCW_ISCW012366.1.1,,,,,,,B2CL1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434] comp137634_c0_seq1,1547,42.5339,0.9062225,5,1338,female>male,5.00E-78,Q6UWX4,HHIP-like protein 2,HHIP-like protein 2,GO:0005975; GO:0005576; GO:0016901; GO:0048038,"carbohydrate metabolic process; extracellular region; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; quinone binding",PF03024;PF07995;,,,,,,,,,HIPL2_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975] comp137636_c0_seq1,1876,41.6844,0.7749491,1757,12237,,3.00E-130,Q7JQD3,Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1),Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1),GO:0003779; GO:0051693; GO:0030043; GO:0030041; GO:0051014; GO:0045010; GO:0005509; GO:0005737; GO:0005856; GO:0007275,actin binding; actin filament capping; actin filament fragmentation; actin filament polymerization; actin filament severing; actin nucleation; calcium ion binding; cytoplasm; cytoskeleton; multicellular organismal development,PF00626;,2.00E-85,CHOYP_GELS2.2.2,4.00E-54,ruditapes2_c841,,,,,GELS1_LUMTE,Lumbricus terrestris (Common earthworm),actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; multicellular organism development [GO:0007275] comp137640_c0_seq12,581,38.0379,0.58847495,0,0,,2.00E-09,Q8BPY9,Fidgetin-like protein 1 (EC 3.6.4.-),Fidgetin-like protein 1 (EC 3.6.4.-),GO:0005524; GO:0046034; GO:0071479; GO:0005737; GO:0016787; GO:0000287; GO:0043066; GO:2001243; GO:0000228; GO:0017111; GO:0001649; GO:0033687; GO:0051726; GO:0010569,ATP binding; ATP metabolic process; cellular response to ionizing radiation; cytoplasm; hydrolase activity; magnesium ion binding; negative regulation of apoptotic process; negative regulation of intrinsic apoptotic signaling pathway; nuclear chromosome; nucleoside-triphosphatase activity; osteoblast differentiation; osteoblast proliferation; regulation of cell cycle; regulation of double-strand break repair via homologous recombination,PF00004;PF09336;,,,,,,,,,FIGL1_MOUSE,Mus musculus (Mouse),ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; cytoplasmic microtubule organization [GO:0031122]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569] comp137640_c0_seq9,525,39.8095,0.44459215,0,0,,3.00E-10,Q8BPY9,Fidgetin-like protein 1 (EC 3.6.4.-),Fidgetin-like protein 1 (EC 3.6.4.-),GO:0005524; GO:0046034; GO:0071479; GO:0005737; GO:0016787; GO:0000287; GO:0043066; GO:2001243; GO:0000228; GO:0017111; GO:0001649; GO:0033687; GO:0051726; GO:0010569,ATP binding; ATP metabolic process; cellular response to ionizing radiation; cytoplasm; hydrolase activity; magnesium ion binding; negative regulation of apoptotic process; negative regulation of intrinsic apoptotic signaling pathway; nuclear chromosome; nucleoside-triphosphatase activity; osteoblast differentiation; osteoblast proliferation; regulation of cell cycle; regulation of double-strand break repair via homologous recombination,PF00004;PF09336;,,,,,,,,,FIGL1_MOUSE,Mus musculus (Mouse),ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; cytoplasmic microtubule organization [GO:0031122]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569] comp137652_c0_seq10,864,27.4306,0.43213018,4,31,,,,,,,,,,,1.00E-12,ruditapes_c4894,,,,,,, comp137652_c0_seq12,457,30.1969,0.38511851,3,4,,,,,,,,,,,2.00E-12,ruditapes_c17027,,,,,,, comp137652_c0_seq9,364,23.3516,0.61310653,37,84,,,,,,,,,,,1.00E-14,ruditapes_c27272,,,,,,, comp137655_c2_seq1,778,39.4602,0.47495941,38,122,,2.00E-87,A2VE52,"Oligoribonuclease, mitochondrial (EC 3.1.-.-) (RNA exonuclease 2 homolog) (Small fragment nuclease)","Oligoribonuclease, mitochondrial (EC 3.1.-.-) (RNA exonuclease 2 homolog) (Small fragment nuclease)",GO:0008408; GO:0005739; GO:0003676; GO:0090305; GO:0005730; GO:0005886,3'-5' exonuclease activity; mitochondrion; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleolus; plasma membrane,PF00929;,1.00E-64,CHOYP_LOC100187372.1.1,,,,,,,ORN_BOVIN,Bos taurus (Bovine),nucleic acid phosphodiester bond hydrolysis [GO:0090305] comp137656_c0_seq1,2212,38.7884,0.4052732,58,4,,3.00E-138,P0C6R2,Armadillo repeat-containing protein 2,Armadillo repeat-containing protein 2,,,,,,,,,,,,ARMC2_BOVIN,Bos taurus (Bovine), comp137656_c0_seq4,1535,40.8469,0.48238196,0,3,,,,,,,,,1.00E-62,CHOYP_LOC100376011.1.1,,,,,,,,, comp137656_c0_seq5,1338,40.8819,0.45704676,0,0,,1.00E-104,P0C6R2,Armadillo repeat-containing protein 2,Armadillo repeat-containing protein 2,,,,,,,,,,,,ARMC2_BOVIN,Bos taurus (Bovine), comp137658_c0_seq1,1249,43.1545,0.74621733,0,0,,2.00E-15,P44849,Uncharacterized sodium-dependent transporter HI_0736,Uncharacterized sodium-dependent transporter HI_0736,GO:0016021; GO:0005328; GO:0005886,integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,7.00E-45,CHOYP_LOC100533491.1.1,2.00E-12,ruditapes2_c2910,,,,,Y736_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),transport [GO:0006810] comp137658_c0_seq11,1920,42.9688,0.81597134,0,0,,2.00E-46,Q96N87,Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3),Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3),GO:0006865; GO:0005887; GO:0005328; GO:0005886; GO:0055085,amino acid transport; integral to plasma membrane; neurotransmitter:sodium symporter activity; plasma membrane; transmembrane transport,PF00209;,,,,,,,,,S6A18_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865] comp137658_c0_seq12,1895,42.8496,0.81953024,0,0,,5.00E-128,Q2PG55,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,5.00E-11,CHOYP_AT1.1.1,,,,,,,S6A13_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp137658_c0_seq2,1594,43.4128,0.77859915,0,0,,2.00E-163,P31646,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0042165; GO:0006836; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter binding; neurotransmitter transport; neurotransmitter:sodium symporter activity,PF00209;,1.00E-36,CHOYP_S6A11.1.1,,,,,,,S6A13_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836] comp137658_c0_seq3,2242,43.2649,0.81384693,0,0,,2.00E-177,P31641,Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6),Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6),GO:0006865; GO:0006520; GO:0016021; GO:0005887; GO:0005328; GO:0005886; GO:0030977; GO:0015734; GO:0005369,amino acid transport; cellular amino acid metabolic process; integral to membrane; integral to plasma membrane; neurotransmitter:sodium symporter activity; plasma membrane; taurine binding; taurine transport; taurine:sodium symporter activity,PF00209;,,,,,,,,,SC6A6_HUMAN,Homo sapiens (Human),amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; cellular amino acid metabolic process [GO:0006520]; taurine transport [GO:0015734]; transport [GO:0006810] comp137658_c0_seq4,2217,43.1664,0.81682846,0,0,,3.00E-175,O35316,Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6),Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6),GO:0005887; GO:0005328; GO:0030977; GO:0005368; GO:0015734; GO:0005369,integral to plasma membrane; neurotransmitter:sodium symporter activity; taurine binding; taurine transmembrane transporter activity; taurine transport; taurine:sodium symporter activity,PF00209;,,,,,,,,,SC6A6_MOUSE,Mus musculus (Mouse),taurine transport [GO:0015734] comp137658_c0_seq5,1818,43.4543,0.8550577,0,0,,1.00E-12,P45320,Uncharacterized sodium-dependent transporter HI_1690,Uncharacterized sodium-dependent transporter HI_1690,GO:0016021; GO:0005328; GO:0005886,integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,,,,,,,,,Y1690_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp137658_c0_seq6,1793,43.3352,0.8595044,0,0,,1.00E-18,P44849,Uncharacterized sodium-dependent transporter HI_0736,Uncharacterized sodium-dependent transporter HI_0736,GO:0016021; GO:0005328; GO:0005886,integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,2.00E-65,CHOYP_LOC100533491.1.1,,,,,,,Y736_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),transport [GO:0006810] comp137658_c0_seq7,1619,43.7925,0.79260204,0,0,,,,,,,,,1.00E-36,CHOYP_S6A11.1.1,,,,,,,,, comp137658_c0_seq8,2115,43.5934,0.8501609,0,0,,0,P31646,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0042165; GO:0006836; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter binding; neurotransmitter transport; neurotransmitter:sodium symporter activity,PF00209;,5.00E-11,CHOYP_AT1.1.1,,,,,,,S6A13_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836] comp137658_c0_seq9,2140,43.6916,0.84655651,0,0,,1.00E-100,B4L7U0,Sodium-dependent nutrient amino acid transporter 1,Sodium-dependent nutrient amino acid transporter 1,GO:0042943; GO:0005887; GO:0005328; GO:0015175; GO:0005283,D-amino acid transmembrane transporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity; neutral amino acid transmembrane transporter activity; sodium:amino acid symporter activity,PF00209;,3.00E-39,CHOYP_SC6A6.2.2,,,,,,,NAAT1_DROMO,Drosophila mojavensis (Fruit fly),D-amino acid transport [GO:0042940]; neutral amino acid transport [GO:0015804]; sodium ion transport [GO:0006814] comp137660_c0_seq1,1579,41.6086,0.43978492,492,283,,5.00E-71,Q91618,Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase),Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase),GO:0005524; GO:0000139; GO:0007049; GO:0005789; GO:0046872; GO:0010923; GO:0004674,ATP binding; Golgi membrane; cell cycle; endoplasmic reticulum membrane; metal ion binding; negative regulation of phosphatase activity; protein serine/threonine kinase activity,PF00069;,8.00E-90,CHOYP_LOC100376881.1.1,,,,,,,PMYT1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; negative regulation of phosphatase activity [GO:0010923] comp137661_c0_seq1,2502,37.0504,0.49545677,2087,9947,,5.00E-132,Q5ZMS3,Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma),Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma),GO:0005525; GO:0006184; GO:0003924; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; translation initiation factor activity,PF09173;PF03144;,0,CHOYP_IF2H.1.1,,,,,,,IF2G_CHICK,Gallus gallus (Chicken),formation of translation preinitiation complex [GO:0001731] comp137665_c0_seq1,1611,40.658,0.85813583,1,38,,2.00E-42,Q26304,Luciferin 4-monooxygenase (Luciferase) (EC 1.13.12.7),Luciferin 4-monooxygenase (Luciferase) (EC 1.13.12.7),GO:0005524; GO:0047077; GO:0008218; GO:0000287; GO:0005777,ATP binding; Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity; bioluminescence; magnesium ion binding; peroxisome,PF00501;PF13193;,,,,,,,,,LUCI_LUCMI,Luciola mingrelica (Southern Russian firefly),bioluminescence [GO:0008218] comp137665_c0_seq2,1523,39.4616,0.9116654,1,0,,2.00E-21,C8VTR6,Putative acyl-coenzyme A synthetase (EC 6.2.1.-),Putative acyl-coenzyme A synthetase (EC 6.2.1.-),GO:1901512; GO:1900617; GO:0006631; GO:0016874; GO:1900815; GO:0005777; GO:0005886; GO:0009847; GO:1900796,(-)-microperfuranone biosynthetic process; emericellamide A biosynthetic process; fatty acid metabolic process; ligase activity; monodictyphenone biosynthetic process; peroxisome; plasma membrane; spore germination; terrequinone A biosynthetic process,PF00501;PF13193;,,,,,,,,,Y0074_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),metabolic process [GO:0008152] comp137667_c0_seq1,2207,37.0639,0.58391295,5596,284,,5.00E-140,Q969V4,Tektin-1,Tektin-1,GO:0035085; GO:0005737; GO:0005874; GO:0000226,cilium axoneme; cytoplasm; microtubule; microtubule cytoskeleton organization,,0,CHOYP_LOC100377173.2.2,,,,,,,TEKT1_HUMAN,Homo sapiens (Human), comp137672_c0_seq1,3800,34.8684,0.47837144,10681,27629,,0,Q3SZ71,Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP),Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP),GO:0046872; GO:0004222; GO:0005759; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; proteolysis,PF00675;PF05193;,1.00E-78,CHOYP_ISCW_ISCW001592.1.2,1.00E-109,ruditapes2_c1656,,,,,MPPB_BOVIN,Bos taurus (Bovine),"aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; protein processing [GO:0016485]" comp137675_c0_seq1,671,39.4933,0.46344931,89,83,,3.00E-39,Q8N7B6,PACRG-like protein,PACRG-like protein,,,PF10274;,,,,,,,,,PACRL_HUMAN,Homo sapiens (Human), comp137675_c0_seq3,325,41.8462,0.35373599,12,0,,,,,,,,,2.00E-12,CHOYP_PACRL.1.1,,,,,,,,, comp137676_c0_seq1,3296,34.7391,0.51807044,4397,25489,,4.00E-156,Q5ZLT7,Basic leucine zipper and W2 domain-containing protein 1,Basic leucine zipper and W2 domain-containing protein 1,GO:0005737; GO:0006355; GO:0006351,"cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02020;,1.00E-123,CHOYP_BZW1.1.1,,,,,,,BZW1_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137677_c0_seq1,1050,43.9048,0.72658206,267,707,,3.00E-73,Q9MYP6,17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3),GO:0005813; GO:0005829; GO:0004303; GO:0006706; GO:0047045,centrosome; cytosol; estradiol 17-beta-dehydrogenase activity; steroid catabolic process; testosterone 17-beta-dehydrogenase (NADP+) activity,,,,2.00E-48,ruditapes_c7690,,,,,DHB14_BOVIN,Bos taurus (Bovine),steroid catabolic process [GO:0006706] comp137682_c0_seq1,499,37.6754,0.50980153,9,541,,,,,,,,,,,2.00E-12,ruditapes_c28149,,,,,,, comp137684_c0_seq8,664,41.5663,0.17592632,266,757,,1.00E-28,Q9U8B8,Dihydrofolate reductase (EC 1.5.1.3),Dihydrofolate reductase (EC 1.5.1.3),GO:0050661; GO:0004146; GO:0006545; GO:0009165; GO:0006730; GO:0046654,NADP binding; dihydrofolate reductase activity; glycine biosynthetic process; nucleotide biosynthetic process; one-carbon metabolic process; tetrahydrofolate biosynthetic process,PF00186;,,,,,,,,,DYR_HELVI,Heliothis virescens (Tobacco budworm moth),glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654] comp137684_c1_seq2,616,40.0974,0.5343073,0,0,,7.00E-60,P00374,Dihydrofolate reductase (EC 1.5.1.3),Dihydrofolate reductase (EC 1.5.1.3),GO:0050661; GO:0005829; GO:0004146; GO:0008144; GO:0046655; GO:0006545; GO:0003729; GO:0046209; GO:0005654; GO:0009165; GO:0006730; GO:0050999; GO:0000083; GO:0031427; GO:0046654; GO:0046653,NADP binding; cytosol; dihydrofolate reductase activity; drug binding; folic acid metabolic process; glycine biosynthetic process; mRNA binding; nitric oxide metabolic process; nucleoplasm; nucleotide biosynthetic process; one-carbon metabolic process; regulation of nitric-oxide synthase activity; regulation of transcription involved in G1/S transition of mitotic cell cycle; response to methotrexate; tetrahydrofolate biosynthetic process; tetrahydrofolate metabolic process,PF00186;,,,,,,,,,DYR_HUMAN,Homo sapiens (Human),axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; G1/S transition of mitotic cell cycle [GO:0000082]; glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653] comp137684_c1_seq3,801,38.8265,0.47339647,0,0,,1.00E-58,Q920D2,Dihydrofolate reductase (EC 1.5.1.3),Dihydrofolate reductase (EC 1.5.1.3),GO:0050661; GO:0046452; GO:0004146; GO:0051871; GO:0008144; GO:0006545; GO:0003729; GO:0009165; GO:0006730; GO:0031427; GO:0035094; GO:0046654,NADP binding; dihydrofolate metabolic process; dihydrofolate reductase activity; dihydrofolic acid binding; drug binding; glycine biosynthetic process; mRNA binding; nucleotide biosynthetic process; one-carbon metabolic process; response to methotrexate; response to nicotine; tetrahydrofolate biosynthetic process,PF00186;,1.00E-14,CHOYP_BRAFLDRAFT_268308.1.1,,,,,,,DYR_RAT,Rattus norvegicus (Rat),axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]; one-carbon metabolic process [GO:0006730]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653] comp137685_c0_seq1,2141,42.1298,1.20081461,745,3698,,4.00E-23,P55041,GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR),GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR),GO:0019003; GO:0005525; GO:0003924; GO:0009898; GO:0000287; GO:0005634; GO:0007264,GDP binding; GTP binding; GTPase activity; internal side of plasma membrane; magnesium ion binding; nucleus; small GTPase mediated signal transduction,PF00071;,,,,,,,,,GEM_MOUSE,Mus musculus (Mouse),chromosome organization [GO:0051276]; metaphase plate congression [GO:0051310]; mitotic nuclear division [GO:0007067]; small GTPase mediated signal transduction [GO:0007264] comp137686_c1_seq1,1613,42.6534,0.80717132,36,160,,3.00E-10,Q6NZL8,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0005509; GO:0009897; GO:0005615; GO:0019897; GO:0046982; GO:0051260,calcium ion binding; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp137686_c1_seq2,1150,43.2174,0.80810236,0,42,,4.00E-12,P01267,Thyroglobulin (Tg),Thyroglobulin (Tg),GO:0005615; GO:0042446; GO:0006590,extracellular space; hormone biosynthetic process; thyroid hormone generation,PF00135;PF07699;PF00086;,,,,,,,,,THYG_BOVIN,Bos taurus (Bovine),hormone biosynthetic process [GO:0042446] comp137689_c1_seq1,525,41.9048,0.17717959,2,0,,6.00E-40,Q9H6P5,Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta],Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta],GO:0045893; GO:0006508; GO:0004298,"positive regulation of transcription, DNA-dependent; proteolysis; threonine-type endopeptidase activity",PF01112;,,,,,,,,,TASP1_HUMAN,Homo sapiens (Human),"positive regulation of transcription, DNA-templated [GO:0045893]; proteolysis [GO:0006508]" comp137689_c1_seq3,486,42.5926,0.14757638,1,0,,5.00E-07,B4JVW6,Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GH22932 (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain],Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GH22932 (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain],GO:0003948; GO:0005764; GO:0008233; GO:0006517; GO:0006508,N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; lysosome; peptidase activity; protein deglycosylation; proteolysis,PF01112;,,,,,,,,,ASPG1_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi),protein deglycosylation [GO:0006517] comp137689_c1_seq7,660,42.4242,0.24321965,7,43,,2.00E-53,Q9H6P5,Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta],Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta],GO:0045893; GO:0006508; GO:0004298,"positive regulation of transcription, DNA-dependent; proteolysis; threonine-type endopeptidase activity",PF01112;,,,,,,,,,TASP1_HUMAN,Homo sapiens (Human),"positive regulation of transcription, DNA-templated [GO:0045893]; proteolysis [GO:0006508]" comp137692_c0_seq1,961,36.1082,0.54765313,95,592,,6.00E-39,Q804H7,Baculoviral IAP repeat-containing protein 5.2-B (Survivin in Xenopus) (SIX) (Survivin2-B) (XSurvivin2B),Baculoviral IAP repeat-containing protein 5.2-B (Survivin in Xenopus) (SIX) (Survivin2-B) (XSurvivin2B),GO:0051301; GO:0032133; GO:0007059; GO:0000777; GO:0005737; GO:0046872; GO:0030496; GO:0007067; GO:0043066; GO:0045892; GO:0005634; GO:0006468; GO:0005819; GO:0001944,"cell division; chromosome passenger complex; chromosome segregation; condensed chromosome kinetochore; cytoplasm; metal ion binding; midbody; mitosis; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent; nucleus; protein phosphorylation; spindle; vasculature development",PF00653;,,,4.00E-13,ruditapes_c8271,,,,,BI52B_XENLA,Xenopus laevis (African clawed frog),"cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; vasculature development [GO:0001944]" comp137695_c1_seq2,820,43.1707,0.43085868,3,0,,7.00E-40,Q9QZR0,E3 ubiquitin-protein ligase RNF25 (EC 6.3.2.-) (RING finger protein 25) (RING finger protein AO7),E3 ubiquitin-protein ligase RNF25 (EC 6.3.2.-) (RING finger protein 25) (RING finger protein AO7),GO:0051059; GO:0005829; GO:0005634; GO:0051092; GO:0004842; GO:0008270,NF-kappaB binding; cytosol; nucleus; positive regulation of NF-kappaB transcription factor activity; ubiquitin-protein ligase activity; zinc ion binding,PF05773;,,,,,,,,,RNF25_MOUSE,Mus musculus (Mouse),positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567] comp137695_c1_seq3,2498,38.1105,0.31302574,177,270,,,,,,,,,2.00E-18,CHOYP_LOC101172160.1.1,,,,,,,,, comp137696_c0_seq2,2687,42.166,0.66303651,7,0,,8.00E-40,Q6IPM2,IQ domain-containing protein E,IQ domain-containing protein E,GO:0005739,mitochondrion,PF00612;,1.00E-27,CHOYP_LOC100888457.2.2,,,,,,,IQCE_HUMAN,Homo sapiens (Human), comp137696_c0_seq3,2714,42.0413,0.65206556,9,6,,,,,,,,,6.00E-31,CHOYP_LOC100888457.1.2,,,,,,,,, comp137701_c1_seq1,419,43.9141,0.39867337,5,0,,1.00E-06,Q5BJ29,F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7),F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7),GO:0000086; GO:0019005; GO:0031146; GO:0051301; GO:0008283; GO:0005813; GO:0005737; GO:0007067; GO:0016567,G2/M transition of mitotic cell cycle; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cell proliferation; centrosome; cytoplasm; mitosis; protein ubiquitination,PF12937;PF13516;,,,,,,,,,FBXL7_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cell proliferation [GO:0008283]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp137701_c1_seq2,2069,37.1194,0.41091962,144,205,,5.00E-47,Q3SYW0,F-box only protein 15,F-box only protein 15,,,PF12937;,,,,,,,,,FBX15_BOVIN,Bos taurus (Bovine),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp137705_c0_seq1,1389,40.5328,0.25277336,3,133,,7.00E-82,Q566U4,Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF),Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF),GO:0034354; GO:0004061; GO:0005829; GO:0005634; GO:0019441,'de novo' NAD biosynthetic process from tryptophan; arylformamidase activity; cytosol; nucleus; tryptophan catabolic process to kynurenine,PF07859;,,,,,,,,,KFA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] comp137713_c1_seq1,1651,42.0351,0.97879585,909,21,,4.00E-12,A7E3C4,Ig-like V-type domain-containing protein FAM187A,Ig-like V-type domain-containing protein FAM187A,GO:0016021,integral to membrane,PF07686;,,,,,,,,,F187A_BOVIN,Bos taurus (Bovine), comp137714_c0_seq2,547,38.2084,1.01032786,0,4,,1.00E-23,A8WFT6,Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81),Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81),GO:0005737; GO:0047992,cytoplasm; hydroxylysine kinase activity,PF01636;,,,,,,,,,AGPD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp137714_c0_seq3,1406,41.8208,1.09244249,45,238,,6.00E-60,A2RU49,Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1),Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1),GO:0005737; GO:0047992,cytoplasm; hydroxylysine kinase activity,PF01636;,,,,,,,,,AGPD1_HUMAN,Homo sapiens (Human),lysine catabolic process [GO:0006554] comp137715_c0_seq1,642,45.1713,0.33666606,33,77,,5.00E-98,Q8N4J0,UPF0586 protein C9orf41,Carnosine N-methyltransferase (EC 2.1.1.22),,,PF07942;,4.00E-63,CHOYP_LOC100561810.1.1,1.00E-11,ruditapes_c26279,,,,,CI041_HUMAN,Homo sapiens (Human),carnosine metabolic process [GO:0035498] comp137720_c2_seq1,1171,34.6712,0.6792418,70,291,,5.00E-37,Q5F3A1,Translocation protein SEC62 (Translocation protein 1) (TP-1),Translocation protein SEC62 (Translocation protein 1) (TP-1),GO:0016235; GO:0005789; GO:0016021; GO:0045111; GO:0008565,aggresome; endoplasmic reticulum membrane; integral to membrane; intermediate filament cytoskeleton; protein transporter activity,PF03839;,2.00E-25,CHOYP_SEC62.2.3,,,,,,,SEC62_CHICK,Gallus gallus (Chicken),posttranslational protein targeting to membrane [GO:0006620] comp137723_c0_seq1,2620,38.8931,0.47108982,3561,68,,4.00E-106,Q0VFN8,Uncharacterized protein C9orf117 homolog,Uncharacterized protein C9orf117 homolog,,,,8.00E-124,CHOYP_LOC100370453.1.1,,,1.00E-91,AM856886.p.cg.6,5,,CI117_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp137725_c0_seq3,232,33.6207,0.61928061,38,141,,,,,,,,,,,7.00E-34,ruditapes2_c1163,,,,,,, comp137725_c0_seq4,305,31.1475,0.55636962,57,387,,,,,,,,,,,2.00E-29,ruditapes_c3510,,,,,,, comp137725_c0_seq5,338,37.8698,0.33309061,216,1003,,,,,,,,,,,5.00E-18,ruditapes_c7836,,,,,,, comp137725_c0_seq7,1971,31.3546,0.24784254,106,148,,,,,,,,,,,5.00E-28,ruditapes_c4549,,,,,,, comp137727_c2_seq1,1921,40.4997,0.46165869,141,1500,,1.00E-167,Q6ZWL3,Cytochrome P450 4V2 (EC 1.14.13.-),Cytochrome P450 4V2 (EC 1.14.13.-) (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.13.199),GO:0005789; GO:0010430; GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705; GO:0050896; GO:0007601,"endoplasmic reticulum membrane; fatty acid omega-oxidation; heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; response to stimulus; visual perception",PF00067;,2.00E-67,CHOYP_CP4V2.1.1,,,,,,,CP4V2_HUMAN,Homo sapiens (Human),fatty acid omega-oxidation [GO:0010430]; response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; sterol metabolic process [GO:0016125]; visual perception [GO:0007601] comp137732_c0_seq1,2022,36.6963,0.3430929,194,944,,3.00E-57,Q0V8M0,Protein KRI1 homolog,Protein KRI1 homolog,,,PF05178;PF12936;,1.00E-37,CHOYP_LOC100489126.1.1,,,,,,,KRI1_BOVIN,Bos taurus (Bovine), comp137733_c1_seq1,1254,48.5646,0.84019058,226,588,,8.00E-39,P49013,Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),GO:0005509; GO:0005615,calcium ion binding; extracellular space,PF01382;PF00431;PF00008;,,,1.00E-14,ruditapes_c9777,,,,,FBP3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp137733_c1_seq2,1334,47.7511,0.85634399,117,422,,6.00E-33,O35516,Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],GO:0007219; GO:0060413; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0061073; GO:0005829; GO:0030326; GO:0005576; GO:0072104; GO:0072015; GO:0001947; GO:0006959; GO:0001701; GO:0002437; GO:0005887; GO:0072602; GO:0070986; GO:0002011; GO:0008285; GO:0000122; GO:0005654; GO:0060674; GO:0030513; GO:0046579; GO:0043065; GO:0008284; GO:0045672; GO:0072014; GO:0006351; GO:0042060,"Notch signaling pathway; atrial septum morphogenesis; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; ciliary body morphogenesis; cytosol; embryonic limb morphogenesis; extracellular region; glomerular capillary formation; glomerular visceral epithelial cell development; heart looping; humoral immune response; in utero embryonic development; inflammatory response to antigenic stimulus; integral to plasma membrane; interleukin-4 secretion; left/right axis specification; morphogenesis of an epithelial sheet; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; placenta blood vessel development; positive regulation of BMP signaling pathway; positive regulation of Ras protein signal transduction; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of osteoclast differentiation; proximal tubule development; transcription, DNA-dependent; wound healing",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_MOUSE,Mus musculus (Mouse),"atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]" comp137734_c0_seq1,1169,38.6655,0.51019839,557,3380,,7.00E-55,Q5I0K7,UDP-N-acetylglucosamine transferase subunit ALG13 homolog (EC 2.4.1.141) (Glycosyltransferase 28 domain-containing protein 1),UDP-N-acetylglucosamine transferase subunit ALG13 homolog (EC 2.4.1.141) (Glycosyltransferase 28 domain-containing protein 1),GO:0004577; GO:0030246; GO:0005783; GO:0030259,N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity; carbohydrate binding; endoplasmic reticulum; lipid glycosylation,PF04101;,,,,,,,,,ALG13_RAT,Rattus norvegicus (Rat), comp137735_c0_seq1,1579,39.1387,0.38472548,9,0,,6.00E-09,C6E6X6,Protein RecA (Recombinase A),Protein RecA (Recombinase A),GO:0005524; GO:0006310; GO:0006281; GO:0008094; GO:0009432; GO:0005737; GO:0003684; GO:0003697,ATP binding; DNA recombination; DNA repair; DNA-dependent ATPase activity; SOS response; cytoplasm; damaged DNA binding; single-stranded DNA binding,PF00154;,,,,,,,,,RECA_GEOSM,Geobacter sp. (strain M21),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432] comp137735_c0_seq2,1736,36.6935,0.36848444,18,0,,6.00E-09,Q5HA31,Protein RecA (Recombinase A),Protein RecA (Recombinase A),GO:0005524; GO:0006310; GO:0006281; GO:0008094; GO:0009432; GO:0005737; GO:0003684; GO:0003697,ATP binding; DNA recombination; DNA repair; DNA-dependent ATPase activity; SOS response; cytoplasm; damaged DNA binding; single-stranded DNA binding,PF00154;,,,,,,,,,RECA_EHRRW,Ehrlichia ruminantium (strain Welgevonden),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432] comp137735_c0_seq4,1567,38.9917,0.33939408,117,45,,0,Q14565,Meiotic recombination protein DMC1/LIM15 homolog,Meiotic recombination protein DMC1/LIM15 homolog,GO:0005524; GO:0003677; GO:0008094; GO:0000781; GO:0000794; GO:0007292; GO:0007141; GO:0001556; GO:0001541; GO:0007131; GO:0007286; GO:0007283; GO:0007129,"ATP binding; DNA binding; DNA-dependent ATPase activity; chromosome, telomeric region; condensed nuclear chromosome; female gamete generation; male meiosis I; oocyte maturation; ovarian follicle development; reciprocal meiotic recombination; spermatid development; spermatogenesis; synapsis",PF08423;,0,CHOYP_DMC1.1.1,,,,,,,DMC1_HUMAN,Homo sapiens (Human),chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; female gamete generation [GO:0007292]; male meiosis I [GO:0007141]; meiotic nuclear division [GO:0007126]; mitotic recombination [GO:0006312]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; strand invasion [GO:0042148]; synapsis [GO:0007129] comp137737_c1_seq1,1870,42.3529,0.7167669,0,0,,2.00E-62,Q9Y4A0,Jerky protein homolog-like (Human homolog of mouse jerky gene protein) (HHMJG),Jerky protein homolog-like (Human homolog of mouse jerky gene protein) (HHMJG),GO:0003677; GO:0007417; GO:0005634,DNA binding; central nervous system development; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,JERKL_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417] comp137737_c1_seq6,1857,42.3802,0.72080714,0,0,,9.00E-69,Q499M4,Tigger transposable element derived 5,Tigger transposable element derived 5,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,1.00E-21,ruditapes_c30170,,,,,TIGD5_MOUSE,Mus musculus (Mouse), comp137738_c1_seq1,2262,43.3245,0.35537821,235,1757,,0,Q3UMC0,Spermatogenesis-associated protein 5 (Spermatogenesis-associated factor protein),Spermatogenesis-associated protein 5 (Spermatogenesis-associated factor protein),GO:0005524; GO:0030154; GO:0005739; GO:0007275; GO:0017111; GO:0007283,ATP binding; cell differentiation; mitochondrion; multicellular organismal development; nucleoside-triphosphatase activity; spermatogenesis,PF00004;,4.00E-120,CHOYP_LOC101072049.1.1,,,,,,,SPAT5_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] comp137739_c1_seq1,329,42.2492,0.27340766,4,46,,2.00E-16,Q8HY87,Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2),Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2),GO:0004519; GO:0046872; GO:0072684; GO:0005739; GO:0005634,"endonuclease activity; metal ion binding; mitochondrial tRNA 3'-trailer cleavage, endonucleolytic; mitochondrion; nucleus",PF12706;PF13691;,,,,,,,,,RNZ2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684]" comp137739_c4_seq1,252,40.4762,0.39454812,5,20,,2.00E-09,Q8TLK5,Ribonuclease Z (RNase Z) (EC 3.1.26.11) (tRNA 3 endonuclease) (tRNase Z),Ribonuclease Z (RNase Z) (EC 3.1.26.11) (tRNA 3 endonuclease) (tRNase Z),GO:0042781; GO:0042779; GO:0008270,3'-tRNA processing endoribonuclease activity; tRNA 3'-trailer cleavage; zinc ion binding,PF12706;,,,,,,,,,RNZ_METAC,Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A), comp137739_c7_seq1,1000,43,0.37495631,28,60,,2.00E-31,Q8HY87,Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2),Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2),GO:0004519; GO:0046872; GO:0072684; GO:0005739; GO:0005634,"endonuclease activity; metal ion binding; mitochondrial tRNA 3'-trailer cleavage, endonucleolytic; mitochondrion; nucleus",PF12706;PF13691;,,,,,,,,,RNZ2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684]" comp137741_c0_seq1,1568,44.3878,0.42759828,11,0,,1.00E-35,Q9XYF6,Myosin-D (MyoD) (TgM-D),Myosin-D (MyoD) (TgM-D),GO:0005524; GO:0005737; GO:0003774; GO:0016459; GO:0005886,ATP binding; cytoplasm; motor activity; myosin complex; plasma membrane,PF00063;,,,,,,,,,MYOD_TOXGO,Toxoplasma gondii, comp137741_c0_seq4,1529,44.6697,0.43301163,0,2,,4.00E-97,Q569U0,Unconventional myosin-XIX,Unconventional myosin-XIX,GO:0005524; GO:0005741; GO:0003774; GO:0016459,ATP binding; mitochondrial outer membrane; motor activity; myosin complex,PF00612;PF00063;,2.00E-15,CHOYP_MYO22.2.2,,,,,,,MYO19_XENLA,Xenopus laevis (African clawed frog), comp137746_c0_seq1,1269,38.2191,0.88277259,0,1353,,5.00E-77,P41932,14-3-3-like protein 1 (Partitioning defective protein 5),14-3-3-like protein 1 (Partitioning defective protein 5),GO:0045167; GO:0005938; GO:0001708; GO:0000132; GO:0030590; GO:0007126; GO:0005634; GO:0009949; GO:0035046; GO:0007346; GO:0010070,asymmetric protein localization involved in cell fate determination; cell cortex; cell fate specification; establishment of mitotic spindle orientation; first cell cycle pseudocleavage; meiosis; nucleus; polarity specification of anterior/posterior axis; pronuclear migration; regulation of mitotic cell cycle; zygote asymmetric cell division,PF00244;,6.00E-14,CHOYP_14332.2.2,4.00E-33,ruditapes_c8400,,,,,14331_CAEEL,Caenorhabditis elegans,asymmetric protein localization involved in cell fate determination [GO:0045167]; cell fate specification [GO:0001708]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of mitotic spindle orientation [GO:0000132]; first cell cycle pseudocleavage [GO:0030590]; meiotic nuclear division [GO:0007126]; polarity specification of anterior/posterior axis [GO:0009949]; pronuclear migration [GO:0035046]; protein export from nucleus [GO:0006611]; regulation of mitotic cell cycle [GO:0007346]; reproduction [GO:0000003]; zygote asymmetric cell division [GO:0010070] comp137752_c0_seq9,606,42.7393,0.65978441,0,91,,,,,,,,,3.00E-52,CHOYP_contig_009415,,,,,,,,, comp137753_c0_seq9,489,30.2658,1.50192199,0,33,,,,,,,,,,,2.00E-12,ruditapes_c15790,,,,,,, comp137754_c0_seq1,1587,45.8097,0.97354666,595,896,,4.00E-131,P42700,60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2),60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2),GO:0003723; GO:0030030; GO:0005737; GO:0046872; GO:0030529,RNA binding; cell projection organization; cytoplasm; metal ion binding; ribonucleoprotein complex,PF05731;,4.00E-17,CHOYP_LOC100634688.6.6,2.00E-69,ruditapes_c16160,,,,,RO60_XENLA,Xenopus laevis (African clawed frog),cell projection organization [GO:0030030] comp137755_c0_seq1,1459,43.1117,0.42863816,252,857,,5.00E-119,Q61425,"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)","Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)",GO:0003857; GO:0070403; GO:0006635; GO:0005743; GO:0005759; GO:0046676; GO:0014823; GO:0042493; GO:0032868,3-hydroxyacyl-CoA dehydrogenase activity; NAD+ binding; fatty acid beta-oxidation; mitochondrial inner membrane; mitochondrial matrix; negative regulation of insulin secretion; response to activity; response to drug; response to insulin stimulus,PF00725;PF02737;,,,3.00E-156,ruditapes2_c537,,,,,HCDH_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868] comp137755_c0_seq2,3934,35.4601,0.42346857,11048,13052,,2.00E-43,P76083,3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.-),3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.-),GO:0003857; GO:0008691; GO:0050662; GO:0006631; GO:0010124,3-hydroxyacyl-CoA dehydrogenase activity; 3-hydroxybutyryl-CoA dehydrogenase activity; coenzyme binding; fatty acid metabolic process; phenylacetate catabolic process,PF00725;PF02737;,,,,,,,,,PAAH_ECOLI,Escherichia coli (strain K12),fatty acid metabolic process [GO:0006631]; phenylacetate catabolic process [GO:0010124] comp137755_c0_seq3,1540,41.6234,0.45156205,55,197,,4.00E-60,Q9RVG1,Probable 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD),Probable 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD),GO:0003857; GO:0008691; GO:0070403; GO:0019605,3-hydroxyacyl-CoA dehydrogenase activity; 3-hydroxybutyryl-CoA dehydrogenase activity; NAD+ binding; butyrate metabolic process,PF00725;PF02737;,,,,,,,,,HBD_DEIRA,Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422),butyrate metabolic process [GO:0019605] comp137758_c0_seq1,2159,41.2228,0.47997829,7,102,,1.00E-122,Q4QQW8,Putative phospholipase B-like 2 (EC 3.1.1.-) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2),Putative phospholipase B-like 2 (EC 3.1.1.-) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2),GO:0016787; GO:0016042; GO:0043202,hydrolase activity; lipid catabolic process; lysosomal lumen,PF04916;,,,2.00E-14,ruditapes_c23063,,,,,PLBL2_RAT,Rattus norvegicus (Rat),lipid catabolic process [GO:0016042] comp137758_c0_seq3,1773,40.3271,0.47195633,4,25,,2.00E-70,Q9XWV2,Putative phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1),Putative phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1),GO:0005576; GO:0016787; GO:0016042,extracellular region; hydrolase activity; lipid catabolic process,PF04916;,7.00E-85,CHOYP_BRAFLDRAFT_287019.1.1,,,,,,,PLBL1_CAEEL,Caenorhabditis elegans,lipid catabolic process [GO:0016042] comp137762_c0_seq1,1605,44.0498,0.32132866,208,225,,9.00E-87,A6H8J1,Protein PRRC1-A (Proline-rich and coiled-coil-containing protein 1-A),Protein PRRC1-A (Proline-rich and coiled-coil-containing protein 1-A),GO:0005794,Golgi apparatus,PF01931;,2.00E-65,CHOYP_PRRC1.1.1,,,,,,,PRRCA_XENLA,Xenopus laevis (African clawed frog), comp137765_c2_seq1,1148,38.3275,1.12038241,81,352,,9.00E-07,Q87TH4,"Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)","Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)",GO:0009234; GO:0008168; GO:0006744,menaquinone biosynthetic process; methyltransferase activity; ubiquinone biosynthetic process,PF01209;,,,,,,,,,UBIE_VIBPA,Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633),aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744] comp137765_c2_seq2,1048,42.271,0.83515685,61,452,,3.00E-08,Q6GGU0,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_STAAR,Staphylococcus aureus (strain MRSA252),menaquinone biosynthetic process [GO:0009234] comp137768_c0_seq1,1112,40.9173,0.88635376,73,450,,2.00E-12,Q5IS52,Neuronal acetylcholine receptor subunit alpha-2,Neuronal acetylcholine receptor subunit alpha-2,GO:0015464; GO:0004889; GO:0005892; GO:0030054; GO:0045211,acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; cell junction; postsynaptic membrane,PF02931;PF02932;,,,,,,,,,ACHA2_PANTR,Pan troglodytes (Chimpanzee),"cation transmembrane transport [GO:0098655]; neuromuscular synaptic transmission [GO:0007274]; response to nicotine [GO:0035094]; synaptic transmission, cholinergic [GO:0007271]" comp137770_c0_seq1,1149,35.6832,0.43887928,360,622,,,,,,,,,1.00E-10,CHOYP_contig_007541,,,,,,,,, comp137773_c0_seq1,983,47.2024,0.65991126,0,0,,3.00E-91,Q61701,ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),GO:0017091; GO:0000166,AU-rich element binding; nucleotide binding,PF00076;,1.00E-98,CHOYP_LOC100168796.1.1,,,,,,,ELAV4_MOUSE,Mus musculus (Mouse),dendrite morphogenesis [GO:0048813]; learning [GO:0007612]; locomotory behavior [GO:0007626] comp137773_c0_seq2,2071,41.381,0.5080591,0,0,,1.00E-135,Q60899,ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Mel-N1),ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Mel-N1),GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,,,,,,,,,ELAV2_MOUSE,Mus musculus (Mouse), comp137773_c0_seq3,2251,40.3376,0.54667636,0,0,,,,,,,,,2.00E-131,CHOYP_LOC659897.1.1,,,,,,,,, comp137773_c0_seq5,953,45.7503,0.68621553,8,0,,7.00E-93,Q61701,ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD),GO:0017091; GO:0000166,AU-rich element binding; nucleotide binding,PF00076;,1.00E-128,CHOYP_LOC100168796.1.1,,,,,,,ELAV4_MOUSE,Mus musculus (Mouse),dendrite morphogenesis [GO:0048813]; learning [GO:0007612]; locomotory behavior [GO:0007626] comp137773_c0_seq6,903,40.9745,0.71318461,0,0,,1.00E-10,Q14103,Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1),Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1),GO:0003723; GO:0006401; GO:0005829; GO:0000398; GO:0005654; GO:0000166; GO:0045893; GO:0043488; GO:0030529; GO:0042162; GO:0006351,"RNA binding; RNA catabolic process; cytosol; mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding; positive regulation of transcription, DNA-dependent; regulation of mRNA stability; ribonucleoprotein complex; telomeric DNA binding; transcription, DNA-dependent",PF08143;PF00076;,,,,,,,,,HNRPD_HUMAN,Homo sapiens (Human),"3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; gene expression [GO:0010467]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to fluoxetine [GO:0014076]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]" comp137775_c0_seq1,2001,34.6827,0.45253176,16212,88714,,8.00E-78,P10111,"Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (p1B15) (p31) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]","Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (p1B15) (p31) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]",GO:0016018; GO:0005829; GO:0005576; GO:0032513; GO:0005634; GO:0003755; GO:0006457; GO:0045069,cyclosporin A binding; cytosol; extracellular region; negative regulation of protein phosphatase type 2B activity; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; regulation of viral genome replication,PF00160;,2.00E-61,CHOYP_PLIM_3654.1.1,4.00E-67,ruditapes2_c368,,,,,PPIA_RAT,Rattus norvegicus (Rat),negative regulation of protein phosphatase type 2B activity [GO:0032513]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of viral genome replication [GO:0045069] comp137775_c1_seq1,524,44.084,0.51185127,5,5,,1.00E-32,P41105,60S ribosomal protein L28,60S ribosomal protein L28,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01778;,3.00E-38,CHOYP_LOC552398.2.2,,,,,,,RL28_MOUSE,Mus musculus (Mouse),positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; translation [GO:0006412] comp137775_c2_seq13,2536,33.2413,0.59470239,6869,14416,,,,,,,,,,,2.00E-16,ruditapes2_lrc5296,,,,,,, comp137775_c2_seq7,804,28.607,0.42608762,110,188,,,,,,,,,,,2.00E-33,ruditapes_c7209,,,,,,, comp137775_c2_seq8,2800,32.3929,0.59058064,8,23,,,,,,,,,,,2.00E-16,ruditapes_lrc39082,,,,,,, comp137775_c3_seq1,501,46.1078,0.48942748,0,0,,1.00E-32,P41105,60S ribosomal protein L28,60S ribosomal protein L28,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01778;,5.00E-35,CHOYP_contig_049638,2.00E-45,ruditapes2_c1614,,,,,RL28_MOUSE,Mus musculus (Mouse),positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; translation [GO:0006412] comp137776_c0_seq3,1840,39.3478,0.34346224,0,0,,3.00E-12,Q6P0N0,Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243),Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243),GO:0034080; GO:0003677; GO:0051301; GO:0003682; GO:0000775; GO:0007067; GO:0005654,"CENP-A containing nucleosome assembly at centromere; DNA binding; cell division; chromatin binding; chromosome, centromeric region; mitosis; nucleoplasm",PF00249;PF09133;,,,,,,,,,M18BP_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; CENP-A containing nucleosome assembly [GO:0034080]; mitotic nuclear division [GO:0007067] comp137777_c2_seq1,1085,35.8525,0.54939074,9,5,,1.00E-27,Q7L3S4,Zinc finger protein 771 (Mesenchymal stem cell protein DSC43),Zinc finger protein 771 (Mesenchymal stem cell protein DSC43),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN771_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137777_c2_seq2,991,36.6297,0.57372517,0,0,,1.00E-25,Q4V8A8,Zinc finger protein 90 (Zfp-90),Zinc finger protein 90 (Zfp-90),GO:0003677; GO:0001078; GO:0046872; GO:0043392; GO:0005634; GO:0045893,"DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; metal ion binding; negative regulation of DNA binding; nucleus; positive regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP90_RAT,Rattus norvegicus (Rat),"negative regulation of DNA binding [GO:0043392]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp137777_c4_seq7,1389,41.0367,0.64027422,10,13,,1.00E-30,O89001,Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180),Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180),GO:0016021; GO:0004181; GO:0006508; GO:0004185; GO:0008270,integral to membrane; metallocarboxypeptidase activity; proteolysis; serine-type carboxypeptidase activity; zinc ion binding,PF00246;,,,,,,,,,CBPD_MOUSE,Mus musculus (Mouse),peptide metabolic process [GO:0006518]; protein processing [GO:0016485] comp137778_c0_seq1,1002,37.2255,0.49956103,185,297,,1.00E-20,B5FXA0,LYR motif-containing protein 5,LYR motif-containing protein 5,,,PF05347;,6.00E-13,CHOYP_LYM5A.1.1,,,,,,,LYRM5_TAEGU,Taeniopygia guttata (Zebra finch) (Poephila guttata), comp137779_c0_seq6,1042,38.1958,0.18492925,0,0,,1.00E-08,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137784_c0_seq1,242,41.7355,0.57222327,0,9,,5.00E-13,Q80V23,Zinc finger protein 32 (Zinc finger protein 637),Zinc finger protein 32 (Zinc finger protein 637),GO:0046872; GO:0003676; GO:0005634,metal ion binding; nucleic acid binding; nucleus,PF00096;,,,,,,,,,ZNF32_MOUSE,Mus musculus (Mouse), comp137784_c0_seq2,522,35.6322,0.72571959,0,0,,6.00E-14,Q9BXA9,Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3),Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3),GO:0003677; GO:0035136; GO:0035137; GO:0046872; GO:0045879; GO:0005634; GO:0021891; GO:0006355; GO:0006351,"DNA binding; forelimb morphogenesis; hindlimb morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; nucleus; olfactory bulb interneuron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,SALL3_HUMAN,Homo sapiens (Human),"forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; neurogenesis [GO:0022008]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]" comp137784_c0_seq3,567,36.1552,0.59482287,1,21,,3.00E-13,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp137784_c3_seq1,2637,43.2689,0.89251016,3392,13,male>female,,,,,,,,2.00E-17,CHOYP_LOC582352.1.1,7.00E-21,ruditapes_c16953,,,,,,, comp137787_c1_seq1,2026,42.0533,0.45252617,21,37,,3.00E-116,Q642H7,Synembryn-A (Protein Ric-8A),Synembryn-A (Protein Ric-8A),GO:0005737; GO:0005085; GO:0005886,cytoplasm; guanyl-nucleotide exchange factor activity; plasma membrane,PF10165;,9.00E-84,CHOYP_PHUM_PHUM060390.1.1,,,,,,,RIC8A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),G-protein coupled receptor signaling pathway [GO:0007186] comp137787_c1_seq2,1465,41.2287,0.44060799,8,8,,5.00E-36,Q61A92,Synembryn (Resistance to inhibitors of cholinesterase protein 8),Synembryn (Resistance to inhibitors of cholinesterase protein 8),GO:0005938; GO:0005085; GO:0007275,cell cortex; guanyl-nucleotide exchange factor activity; multicellular organismal development,PF10165;,,,,,,,,,RIC8_CAEBR,Caenorhabditis briggsae,G-protein coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275] comp137788_c0_seq1,1955,39.5908,0.42293673,0,0,,7.00E-09,O93327,Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y),Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y),GO:0003677; GO:0016568; GO:0000786; GO:0006334; GO:0005634,DNA binding; chromatin modification; nucleosome; nucleosome assembly; nucleus,PF00125;PF16211;PF01661;,,,,,,,,,H2AY_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; regulation of histone methylation [GO:0031060]; regulation of lipid metabolic process [GO:0019216]" comp137788_c0_seq11,709,45.6982,0.38297129,0,0,,2.00E-07,A4W960,O-acetyl-ADP-ribose deacetylase (EC 3.5.1.-) (Regulator of RNase III activity),O-acetyl-ADP-ribose deacetylase (EC 3.5.1.-) (Regulator of RNase III activity),GO:0019213; GO:0060701; GO:0001883; GO:0042278; GO:0008428,deacetylase activity; negative regulation of ribonuclease activity; purine nucleoside binding; purine nucleoside metabolic process; ribonuclease inhibitor activity,PF01661;,,,,,,,,,YMDB_ENT38,Enterobacter sp. (strain 638),negative regulation of ribonuclease activity [GO:0060701]; purine nucleoside metabolic process [GO:0042278] comp137788_c0_seq4,2198,40.7643,0.44654405,0,0,,3.00E-30,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137788_c0_seq5,2106,40.2659,0.43047198,0,0,,7.00E-27,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137788_c0_seq6,1897,39.2725,0.44170695,0,0,,6.00E-09,Q9WYX8,Uncharacterized protein TM_0508,Uncharacterized protein TM_0508,GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009378,ATP binding; DNA binding; DNA recombination; DNA repair; DNA replication; four-way junction helicase activity,PF16193;PF01661;PF12002;PF05496;,,,,,,,,,Y508_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp137789_c0_seq1,1673,42.1996,0.42187172,9,20,,2.00E-10,P52495,Ubiquitin-activating enzyme E1 1,Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45),GO:0005524; GO:0005737; GO:0016874; GO:0005634; GO:0016567; GO:0008641,ATP binding; cytoplasm; ligase activity; nucleus; protein ubiquitination; small protein activating enzyme activity,PF16191;PF16190;PF09358;PF00899;PF10585;,,,,,,,,,UBA1_CANAW,Candida albicans (strain WO-1) (Yeast),protein ubiquitination [GO:0016567] comp137789_c0_seq2,1607,41.8793,0.43293324,11,14,,0,Q7SXP2,NEDD8-activating enzyme E1 regulatory subunit (APP-BP1) (Amyloid protein-binding protein 1),NEDD8-activating enzyme E1 regulatory subunit (APP-BP1) (Amyloid protein-binding protein 1),GO:0003824; GO:0045116,catalytic activity; protein neddylation,PF00899;,1.00E-124,CHOYP_NEMVEDRAFT_V1G182319.1.1,,,,,,,ULA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein neddylation [GO:0045116] comp137792_c1_seq1,1512,44.1138,0.93624575,47,286,,2.00E-22,Q7TM99,Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9),Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9),GO:0016021; GO:0005886; GO:0015293; GO:0046415,integral to membrane; plasma membrane; symporter activity; urate metabolic process,PF07690;,,,,,,,,,MOT9_MOUSE,Mus musculus (Mouse),urate metabolic process [GO:0046415] comp137797_c0_seq1,1375,40.5091,0.5203153,945,1359,,9.00E-45,Q9D7A8,Armadillo repeat-containing protein 1,Armadillo repeat-containing protein 1,GO:0046872; GO:0030001; GO:0005739,metal ion binding; metal ion transport; mitochondrion,PF00514;,2.00E-20,CHOYP_BRAFLDRAFT_87849.1.1,,,,,,,ARMC1_MOUSE,Mus musculus (Mouse),metal ion transport [GO:0030001] comp137798_c1_seq1,4329,44.1441,0.48030271,13,0,,5.00E-89,P37297,Phosphatidylinositol 4-kinase STT4 (PI4-kinase) (PtdIns-4-kinase) (EC 2.7.1.67),Phosphatidylinositol 4-kinase STT4 (PI4-kinase) (PtdIns-4-kinase) (EC 2.7.1.67),GO:0004430; GO:0005524; GO:0048015; GO:0005886,1-phosphatidylinositol 4-kinase activity; ATP binding; phosphatidylinositol-mediated signaling; plasma membrane,PF00454;PF00613;,0,CHOYP_PI4KA.1.1,,,,,,,STT4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cortical actin cytoskeleton organization [GO:0030866]; macroautophagy [GO:0016236]; mitophagy [GO:0000422]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; regulation of fungal-type cell wall organization [GO:0060237] comp137798_c1_seq2,4383,44.0338,0.47687023,6,0,,0,P42356,Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67),Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67),GO:0004430; GO:0005524; GO:0005798; GO:0005829; GO:0006661; GO:0048015; GO:0005886; GO:0007165; GO:0044281; GO:0007268,1-phosphatidylinositol 4-kinase activity; ATP binding; Golgi-associated vesicle; cytosol; phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling; plasma membrane; signal transduction; small molecule metabolic process; synaptic transmission,PF00454;PF00613;,0,CHOYP_ISCW_ISCW015061.1.1,,,,,,,PI4KA_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165] comp137798_c1_seq3,2174,45.2162,0.46976252,3,0,,0,P42356,Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67),Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67),GO:0004430; GO:0005524; GO:0005798; GO:0005829; GO:0006661; GO:0048015; GO:0005886; GO:0007165; GO:0044281; GO:0007268,1-phosphatidylinositol 4-kinase activity; ATP binding; Golgi-associated vesicle; cytosol; phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling; plasma membrane; signal transduction; small molecule metabolic process; synaptic transmission,PF00454;PF00613;,1.00E-140,CHOYP_PI4KA.1.1,,,,,,,PI4KA_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165] comp137800_c0_seq1,1614,43.1227,0.40326959,0,0,,3.00E-07,P53038,Telomere length regulation protein TEL2,Telomere length regulation protein TEL2,GO:0000783; GO:0034502; GO:0007004; GO:0042162,nuclear telomere cap complex; protein localization to chromosome; telomere maintenance via telomerase; telomeric DNA binding,PF10193;,,,,,,,,,TEL2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein localization to chromosome [GO:0034502]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] comp137800_c0_seq2,1737,44.1566,0.41738727,0,0,,3.00E-104,Q9DC40,Telomere length regulation protein TEL2 homolog,Telomere length regulation protein TEL2 homolog,GO:0031931; GO:0031932; GO:0000781; GO:0005737; GO:0016020; GO:0005634; GO:0032403; GO:0032947; GO:0032006,"TORC1 complex; TORC2 complex; chromosome, telomeric region; cytoplasm; membrane; nucleus; protein complex binding; protein complex scaffold; regulation of TOR signaling cascade",PF10193;,5.00E-17,CHOYP_LOC588739.1.1,,,,,,,TELO2_MOUSE,Mus musculus (Mouse),positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006] comp137800_c0_seq6,1132,44.788,0.42713112,0,0,,4.00E-78,Q6GPP1,Telomere length regulation protein TEL2 homolog,Telomere length regulation protein TEL2 homolog,GO:0000781; GO:0005737; GO:0016020; GO:0005634,"chromosome, telomeric region; cytoplasm; membrane; nucleus",PF10193;,3.00E-17,CHOYP_LOC588739.1.1,,,,,,,TELO2_XENLA,Xenopus laevis (African clawed frog), comp137802_c0_seq2,992,45.5645,0.43345282,15,25,,2.00E-106,Q7TNE1,Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13),Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (SuccinylCoA:glutarate-CoA transferase),GO:0005739; GO:0047369,mitochondrion; succinate-hydroxymethylglutarate CoA-transferase activity,PF02515;,2.00E-57,CHOYP_LOC101160363.1.1,,,,,,,CG010_MOUSE,Mus musculus (Mouse), comp137806_c0_seq1,1209,37.3863,0.59603603,222,969,,3.00E-74,Q9NPD8,Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Cell proliferation-inducing gene 50 protein) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T),Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T),GO:0005524; GO:0006281; GO:0003682; GO:0005654; GO:0070979; GO:0044314; GO:0035519; GO:0070936; GO:0085020; GO:0070534; GO:0051865; GO:0006513; GO:0004842,ATP binding; DNA repair; chromatin binding; nucleoplasm; protein K11-linked ubiquitination; protein K27-linked ubiquitination; protein K29-linked ubiquitination; protein K48-linked ubiquitination; protein K6-linked ubiquitination; protein K63-linked ubiquitination; protein autoubiquitination; protein monoubiquitination; ubiquitin-protein ligase activity,PF00179;,9.00E-50,CHOYP_LOC586901.1.1,,,,,,,UBE2T_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513] comp137811_c0_seq1,1948,42.4538,0.48753452,20,35,,7.00E-161,Q2YDU8,Protein spinster homolog 1,Protein spinster homolog 1,GO:0016021; GO:0006869; GO:0005743; GO:0055085,integral to membrane; lipid transport; mitochondrial inner membrane; transmembrane transport,PF07690;,2.00E-91,CHOYP_SPNS1.1.1,,,,,,,SPNS1_RAT,Rattus norvegicus (Rat),locomotion [GO:0040011]; sphingosine-1-phosphate signaling pathway [GO:0003376]; transmembrane transport [GO:0055085] comp137811_c0_seq2,1836,42.756,0.46169835,0,21,,5.00E-161,Q2YDU8,Protein spinster homolog 1,Protein spinster homolog 1,GO:0016021; GO:0006869; GO:0005743; GO:0055085,integral to membrane; lipid transport; mitochondrial inner membrane; transmembrane transport,PF07690;,1.00E-88,CHOYP_LOC100565194.1.1,,,,,,,SPNS1_RAT,Rattus norvegicus (Rat),locomotion [GO:0040011]; sphingosine-1-phosphate signaling pathway [GO:0003376]; transmembrane transport [GO:0055085] comp137814_c0_seq1,1511,38.8484,0.62103956,9,120,,4.00E-104,Q29RI9,Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta),Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta),GO:0006556; GO:0008831; GO:0045226; GO:0048269; GO:0048270; GO:0005739; GO:0005634; GO:0006730,S-adenosylmethionine biosynthetic process; dTDP-4-dehydrorhamnose reductase activity; extracellular polysaccharide biosynthetic process; methionine adenosyltransferase complex; methionine adenosyltransferase regulator activity; mitochondrion; nucleus; one-carbon metabolic process,PF04321;,3.00E-19,CHOYP_LOC100371994.1.1,,,,,,,MAT2B_BOVIN,Bos taurus (Bovine),one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] comp137815_c0_seq1,1443,45.045,0.86599628,67,196,,9.00E-24,Q5ZIJ9,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,4.00E-14,ruditapes2_c1745,,,,,MIB2_CHICK,Gallus gallus (Chicken),Notch signaling pathway [GO:0007219] comp137819_c0_seq1,1244,35.0482,1.12935963,1892,959,,2.00E-15,Q91ZX1,CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing non-integrin) (DC-SIGN) (CD antigen CD209),CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing non-integrin) (DC-SIGN) (CD antigen CD209),GO:0009986; GO:0006897; GO:0016021; GO:0005537; GO:0046872,cell surface; endocytosis; integral to membrane; mannose binding; metal ion binding,PF00059;,,,,,,,,,C209A_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468]; regulation of T cell proliferation [GO:0042129] comp137824_c1_seq1,2137,45.8587,0.54509142,56,27,,4.00E-116,Q8C761,WD repeat-containing protein 60,WD repeat-containing protein 60,GO:0005929,cilium,PF00400;,,,,,,,,,WDR60_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030] comp137824_c1_seq2,2056,45.963,0.51735425,46,53,,3.00E-116,Q8C761,WD repeat-containing protein 60,WD repeat-containing protein 60,GO:0005929,cilium,PF00400;,5.00E-56,CHOYP_LOC100373809.1.2,,,,,,,WDR60_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030] comp137832_c0_seq2,1272,34.1981,0.56798998,255,1012,,2.00E-56,Q4S2L4,2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-),2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-),GO:0005737; GO:0070694; GO:0009159; GO:0050144; GO:0009117; GO:0005634; GO:0030307,cytoplasm; deoxyribonucleoside 5'-monophosphate N-glycosidase activity; deoxyribonucleoside monophosphate catabolic process; nucleoside deoxyribosyltransferase activity; nucleotide metabolic process; nucleus; positive regulation of cell growth,PF05014;,,,,,,,,,RCL_TETNG,Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis),deoxyribonucleoside monophosphate catabolic process [GO:0009159]; nucleoside metabolic process [GO:0009116]; nucleotide metabolic process [GO:0009117]; positive regulation of cell growth [GO:0030307] comp137833_c3_seq1,304,43.4211,0.49296308,4,19,,,,,,,,,2.00E-32,CHOYP_DOCK1.2.2,,,,,,,,, comp137833_c3_seq3,317,41.9558,0.46356146,2,0,,2.00E-40,Q92608,Dedicator of cytokinesis protein 2,Dedicator of cytokinesis protein 2,GO:0030675; GO:0030676; GO:0042608; GO:0030036; GO:0046633; GO:0006935; GO:0005856; GO:0005829; GO:0012505; GO:0001768; GO:0001771; GO:0044351; GO:0016020; GO:0001766; GO:0002277; GO:0045060; GO:0050766; GO:0045059; GO:0050690; GO:0007264; GO:0016032,Rac GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; actin cytoskeleton organization; alpha-beta T cell proliferation; chemotaxis; cytoskeleton; cytosol; endomembrane system; establishment of T cell polarity; immunological synapse formation; macropinocytosis; membrane; membrane raft polarization; myeloid dendritic cell activation involved in immune response; negative thymic T cell selection; positive regulation of phagocytosis; positive thymic T cell selection; regulation of defense response to virus by virus; small GTPase mediated signal transduction; viral process,PF06920;PF14429;PF16172;,,,,,,,,,DOCK2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; alpha-beta T cell proliferation [GO:0046633]; chemotaxis [GO:0006935]; establishment of T cell polarity [GO:0001768]; immunological synapse formation [GO:0001771]; macropinocytosis [GO:0044351]; membrane raft polarization [GO:0001766]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative thymic T cell selection [GO:0045060]; positive regulation of phagocytosis [GO:0050766]; positive thymic T cell selection [GO:0045059]; regulation of defense response to virus by virus [GO:0050690]; small GTPase mediated signal transduction [GO:0007264] comp137838_c0_seq2,1927,40.8926,0.84687826,8,30,,3.00E-57,Q08AW5,UPF0415 protein C7orf25 homolog,UPF0415 protein C7orf25 homolog,,,PF07000;,,,,,,,,,CG025_XENLA,Xenopus laevis (African clawed frog), comp137838_c0_seq7,1842,40.608,0.83117682,3,0,,5.00E-38,Q08AW5,UPF0415 protein C7orf25 homolog,UPF0415 protein C7orf25 homolog,,,PF07000;,7.00E-15,CHOYP_CG025.1.1,,,,,,,CG025_XENLA,Xenopus laevis (African clawed frog), comp137840_c0_seq1,2508,36.4035,0.54722724,13,0,,4.00E-175,Q8IY84,Serine/threonine-protein kinase NIM1 (EC 2.7.11.1),Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase),GO:0005524; GO:0000287; GO:0004674,ATP binding; magnesium ion binding; protein serine/threonine kinase activity,PF00069;,5.00E-152,CHOYP_BRAFLDRAFT_70429.1.1,,,,,,,NIM1_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp137841_c1_seq1,3226,45.6293,0.58758309,132,106,,0,P49641,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0004572; GO:0043687; GO:0018279; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; post-translational protein modification; protein N-linked glycosylation via asparagine; zinc ion binding",PF09261;PF01074;PF07748;,8.00E-106,CHOYP_MA2A2.1.1,,,,,,,MA2A2_HUMAN,Homo sapiens (Human),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp137842_c0_seq1,12831,44.5562,0.56413652,13226,30702,,0,Q80X90,Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin),Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin),GO:0030018; GO:0005938; GO:0005737; GO:0005925; GO:0007519; GO:0001725,Z disc; cell cortex; cytoplasm; focal adhesion; skeletal muscle tissue development; stress fiber,PF00307;PF00630;,0,CHOYP_contig_019041,,,4.00E-128,FP000131.p.cg.6,10,,FLNB_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; skeletal muscle tissue development [GO:0007519] comp137843_c0_seq1,1552,38.5954,0.50326314,53,578,,2.00E-19,O02350,Zinc carboxypeptidase A 1 (EC 3.4.17.-) (AgCP),Zinc carboxypeptidase A 1 (EC 3.4.17.-) (AgCP),GO:0007586; GO:0005615; GO:0004181; GO:0006508; GO:0008270,digestion; extracellular space; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;PF02244;,1.00E-29,CHOYP_LOC100367625.1.1,,,,,,,CBPA1_ANOGA,Anopheles gambiae (African malaria mosquito),digestion [GO:0007586] comp137848_c0_seq1,1273,39.0416,0.52216571,180,1123,,2.00E-08,Q9D8P7,General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6),General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6),GO:0003677; GO:0000127; GO:0006383,DNA binding; transcription factor TFIIIC complex; transcription from RNA polymerase III promoter,PF10419;,,,,,,,,,TF3C6_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]" comp137849_c5_seq1,2083,37.782,0.55317178,425,2822,,1.00E-31,Q6WAU1,(-)-isopiperitenone reductase (EC 1.3.1.82),(-)-isopiperitenone reductase (EC 1.3.1.82),GO:0052581; GO:0070402; GO:0005737; GO:0031525; GO:0042214,(-)-isopiperitenone reductase activity; NADPH binding; cytoplasm; menthol biosynthetic process; terpene metabolic process,PF00106;,3.00E-40,CHOYP_LOC100366455.3.3,,,,,,,IPIPR_MENPI,Mentha piperita (Peppermint) (Mentha aquatica ? Mentha spicata),menthol biosynthetic process [GO:0031525]; terpene metabolic process [GO:0042214] comp137849_c5_seq2,2043,38.0323,0.50137242,188,1518,,4.00E-97,P48758,Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.197) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189),Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.197) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189),GO:0047021; GO:0004090; GO:0005737; GO:0017144; GO:0050221; GO:0042373,15-hydroxyprostaglandin dehydrogenase (NADP+) activity; carbonyl reductase (NADPH) activity; cytoplasm; drug metabolic process; prostaglandin-E2 9-reductase activity; vitamin K metabolic process,PF00106;,,,,,,,,,CBR1_MOUSE,Mus musculus (Mouse),drug metabolic process [GO:0017144]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373] comp137851_c2_seq1,1487,35.5077,0.6302233,330,1271,,7.00E-99,Q3T0T7,GTP-binding protein SAR1b,GTP-binding protein SAR1b,GO:0005525; GO:0032580; GO:0005789; GO:0006886; GO:0046872; GO:0016192,GTP binding; Golgi cisterna membrane; endoplasmic reticulum membrane; intracellular protein transport; metal ion binding; vesicle-mediated transport,PF00025;,5.00E-123,CHOYP_LOC100371319.1.1,,,,,,,SAR1B_BOVIN,Bos taurus (Bovine),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp137857_c0_seq1,1755,38.1766,0.48010952,112,596,,2.00E-81,Q5ZMH6,Methyltransferase-like protein 9,Methyltransferase-like protein 9,,,PF05219;,3.00E-25,CHOYP_METL9.1.1,,,,,,,METL9_CHICK,Gallus gallus (Chicken), comp137858_c2_seq1,275,45.4545,0.28483349,2,88,,,,,,,,,6.00E-12,CHOYP_LOC662357.1.1,,,,,,,,, comp137859_c0_seq4,1226,37.3573,0.35454254,0,0,,8.00E-11,Q8R3W5,tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15),tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15),GO:0006397; GO:0005730; GO:0006388; GO:0000213,"mRNA processing; nucleolus; tRNA splicing, via endonucleolytic cleavage and ligation; tRNA-intron endonuclease activity",PF09631;,,,,,,,,,SEN15_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp137860_c2_seq1,1663,37.6428,0.49510729,1105,108,,1.00E-77,Q9H095,IQ domain-containing protein G,IQ domain-containing protein G,,,PF00612;,2.00E-161,CHOYP_NEMVEDRAFT_V1G167758.1.1,,,,,,,IQCG_HUMAN,Homo sapiens (Human),spermatid development [GO:0007286]; sperm axoneme assembly [GO:0007288] comp137862_c0_seq1,1920,39.0104,0.83829135,70,716,,5.00E-15,Q5E9A5,Growth arrest and DNA damage-inducible protein GADD45 beta,Growth arrest and DNA damage-inducible protein GADD45 beta,GO:0000186; GO:0006915; GO:0030154; GO:0007275; GO:0006469; GO:0005634; GO:0051726; GO:0006950,activation of MAPKK activity; apoptotic process; cell differentiation; multicellular organismal development; negative regulation of protein kinase activity; nucleus; regulation of cell cycle; response to stress,PF01248;,,,,,,,,,GA45B_BOVIN,Bos taurus (Bovine),activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950] comp137863_c0_seq1,1136,38.5563,0.44825582,28,83,,6.00E-66,Q6GNN8,Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c),Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c),GO:0005829; GO:0031902; GO:0015031,cytosol; late endosome membrane; protein transport,PF03357;,,,,,,,,,CHM4C_XENLA,Xenopus laevis (African clawed frog),abscission [GO:0009838]; negative regulation of cytokinesis [GO:0032466]; protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp137863_c0_seq2,1093,38.7923,0.43715807,45,68,,7.00E-80,Q5XGW6,Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b),Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b),GO:0005829; GO:0031902; GO:0015031,cytosol; late endosome membrane; protein transport,PF03357;,3.00E-81,CHOYP_LOC100367460.1.1,,,,,,,CHM4B_XENLA,Xenopus laevis (African clawed frog),exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; nuclear envelope reassembly [GO:0031468]; protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp137870_c0_seq1,867,36.5629,0.17337831,0,0,,,,,,,,,2.00E-30,CHOYP_ADAL.1.1,,,,,,,,, comp137870_c0_seq3,1295,39.2278,0.26435715,30,153,,6.00E-126,Q6DHV7,Adenosine deaminase-like protein (EC 3.5.4.-),Adenosine deaminase-like protein (EC 3.5.4.-),GO:0006154; GO:0004000; GO:0005829; GO:0017144; GO:0046103; GO:0046872; GO:0009117; GO:0006144; GO:0009168; GO:0043101,adenosine catabolic process; adenosine deaminase activity; cytosol; drug metabolic process; inosine biosynthetic process; metal ion binding; nucleotide metabolic process; purine nucleobase metabolic process; purine ribonucleoside monophosphate biosynthetic process; purine-containing compound salvage,PF00962;,,,3.00E-40,ruditapes_c24256,,,,,ADAL_HUMAN,Homo sapiens (Human),adenosine catabolic process [GO:0006154]; drug metabolic process [GO:0017144]; inosine biosynthetic process [GO:0046103]; nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101] comp137872_c1_seq1,785,36.6879,0.37921613,503,565,,,,,,,,,,,1.00E-12,ruditapes_c5671,,,,,,, comp137875_c2_seq1,2183,35.7306,0.66789449,1213,4702,,1.00E-120,Q6NU94,tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase),tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase),GO:0005634; GO:0008176; GO:0000049,nucleus; tRNA (guanine-N7-)-methyltransferase activity; tRNA binding,PF02390;,2.00E-42,CHOYP_BRAFLDRAFT_119955.1.1,,,,,,,TRMB_XENLA,Xenopus laevis (African clawed frog),tRNA modification [GO:0006400] comp137878_c0_seq1,1126,38.1883,0.7595006,0,0,,2.00E-70,Q86XE3,"Calcium uptake protein 3, mitochondrial (EF-hand domain-containing family member A2)","Calcium uptake protein 3, mitochondrial (EF-hand domain-containing family member A2)",GO:0005509; GO:0016021; GO:0005739,calcium ion binding; integral to membrane; mitochondrion,PF13833;,2.00E-71,CHOYP_AGAP_AGAP004179.1.1,,,,,,,EFHA2_HUMAN,Homo sapiens (Human), comp137878_c0_seq2,1646,39.0644,0.78653324,0,0,,1.00E-38,B1H2N3,"Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)","Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)",GO:0005509; GO:0070509; GO:0032592; GO:0051560; GO:0006851; GO:0005743,calcium ion binding; calcium ion import; integral to mitochondrial membrane; mitochondrial calcium ion homeostasis; mitochondrial calcium ion transport; mitochondrial inner membrane,PF13202;PF13833;,,,,,,,,,MICU1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] comp137878_c0_seq3,1641,39.1225,0.7848645,0,0,,1.00E-84,Q8IYU8,"Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)","Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)",GO:0034704; GO:0005509; GO:0051561; GO:0006851; GO:0005739,calcium channel complex; calcium ion binding; elevation of mitochondrial calcium ion concentration; mitochondrial calcium ion transport; mitochondrion,PF13833;,3.00E-12,CHOYP_contig_005243,,,,,,,EFHA1_HUMAN,Homo sapiens (Human),mitochondrial calcium ion transport [GO:0006851]; negative regulation of mitochondrial calcium ion concentration [GO:0051562]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] comp137878_c0_seq4,1131,38.1079,0.76187641,0,0,,1.00E-20,D2HZB0,"Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)","Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)",GO:0005509; GO:0070509; GO:0032592; GO:0051560; GO:0006851; GO:0005743,calcium ion binding; calcium ion import; integral to mitochondrial membrane; mitochondrial calcium ion homeostasis; mitochondrial calcium ion transport; mitochondrial inner membrane,PF13202;PF13833;,1.00E-72,CHOYP_CG4662.1.1,,,,,,,MICU1_AILME,Ailuropoda melanoleuca (Giant panda),calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] comp137878_c0_seq6,1755,39.4872,0.82823239,0,0,,,,,,,,,2.00E-72,CHOYP_CG4662.1.1,,,,,,,,, comp137878_c0_seq7,1750,39.5429,0.82613851,0,0,,,,,,,,,6.00E-104,CHOYP_AGAP_AGAP004179.1.1,,,,,,,,, comp137878_c0_seq8,515,40.1942,0.97340492,0,0,,,,,,,,,8.00E-14,CHOYP_contig_005243,,,,,,,,, comp137879_c0_seq1,262,64.1221,0.71838309,0,35,,1.00E-17,P16881,"Ribulose bisphosphate carboxylase small chains, chloroplastic (RuBisCO small subunits) (EC 4.1.1.39) [Cleaved into: Ribulose bisphosphate carboxylase small chain P1, chloroplastic; Ribulose bisphosphate carboxylase small chain P2, chloroplastic; Ribulose bisphosphate carboxylase small chain P3, chloroplastic; Ribulose bisphosphate carboxylase small chain P4, chloroplastic; Ribulose bisphosphate carboxylase small chain P5, chloroplastic; Ribulose bisphosphate carboxylase small chain P6, chloroplastic; Ribulose bisphosphate carboxylase small chain P7, chloroplastic; Ribulose bisphosphate carboxylase small chain P8, chloroplastic]","Ribulose bisphosphate carboxylase small chains, chloroplastic (RuBisCO small subunits) (EC 4.1.1.39) [Cleaved into: Ribulose bisphosphate carboxylase small chain P1, chloroplastic; Ribulose bisphosphate carboxylase small chain P2, chloroplastic; Ribulose bisphosphate carboxylase small chain P3, chloroplastic; Ribulose bisphosphate carboxylase small chain P4, chloroplastic; Ribulose bisphosphate carboxylase small chain P5, chloroplastic; Ribulose bisphosphate carboxylase small chain P6, chloroplastic; Ribulose bisphosphate carboxylase small chain P7, chloroplastic; Ribulose bisphosphate carboxylase small chain P8, chloroplastic]",GO:0009507; GO:0004497; GO:0009853; GO:0019253; GO:0016984,chloroplast; monooxygenase activity; photorespiration; reductive pentose-phosphate cycle; ribulose-bisphosphate carboxylase activity,PF00101;,,,,,,,,,RBS_EUGGR,Euglena gracilis,photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253] comp137880_c1_seq3,668,44.9102,0.7933789,0,2,,1.00E-38,Q9U308,Juxtamembrane domain-associated catenin (p120 catenin homolog),Juxtamembrane domain-associated catenin (p120 catenin homolog),GO:0007155; GO:0005913; GO:0010172; GO:0032956; GO:0032880,cell adhesion; cell-cell adherens junction; embryonic body morphogenesis; regulation of actin cytoskeleton organization; regulation of protein localization,PF00514;PF00041;,1.00E-12,CHOYP_CTND2.1.1,,,,,,,JAC1_CAEEL,Caenorhabditis elegans,embryonic body morphogenesis [GO:0010172]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; single organismal cell-cell adhesion [GO:0016337] comp137880_c1_seq6,870,46.092,0.66437921,15,20,,7.00E-71,P98203,Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog,Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog,GO:0016339; GO:0005737; GO:0005634; GO:0005886,calcium-dependent cell-cell adhesion; cytoplasm; nucleus; plasma membrane,PF00514;,,,,,,,,,ARVC_MOUSE,Mus musculus (Mouse),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; multicellular organism development [GO:0007275]; single organismal cell-cell adhesion [GO:0016337] comp137881_c0_seq1,704,42.1875,0.2889087,17,32,,3.00E-88,A6QLJ3,"Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)","Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)",GO:0005525; GO:0006184; GO:0003924; GO:0005743; GO:0006412,GTP binding; GTP catabolic process; GTPase activity; mitochondrial inner membrane; translation,PF00679;PF03144;PF06421;,,,,,,,,,GUF1_BOVIN,Bos taurus (Bovine),positive regulation of translation [GO:0045727]; translation [GO:0006412] comp137881_c1_seq1,369,44.4444,0.3854195,13,26,,3.00E-44,C4JWU3,"Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)","Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)",GO:0005525; GO:0006184; GO:0003924; GO:0005743; GO:0006412,GTP binding; GTP catabolic process; GTPase activity; mitochondrial inner membrane; translation,PF00679;PF06421;,2.00E-39,CHOYP_GUF1.1.2,,,,,,,GUF1_UNCRE,Uncinocarpus reesii (strain UAMH 1704),positive regulation of translation [GO:0045727]; translation [GO:0006412] comp137881_c2_seq1,403,37.469,0.79216174,4,31,,5.00E-44,Q8P173,Putative elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA homolog),Putative elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA homolog),GO:0005525; GO:0006184; GO:0003924; GO:0005886; GO:0045727; GO:0043022; GO:0003746; GO:0006414,GTP binding; GTP catabolic process; GTPase activity; plasma membrane; positive regulation of translation; ribosome binding; translation elongation factor activity; translational elongation,PF00679;PF06421;,,,3.00E-16,ruditapes_c29949,,,,,LEPA_STRP8,Streptococcus pyogenes serotype M18 (strain MGAS8232),translation [GO:0006412] comp137884_c0_seq2,679,44.3299,0.57437663,56,124,,8.00E-38,Q9QZN1,F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13),F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13),,,PF12937;PF13516;,,,,,,,,,FXL17_MOUSE,Mus musculus (Mouse), comp137886_c1_seq1,1401,39.6859,0.56262974,88,277,,8.00E-35,Q9NYT6,Zinc finger protein 226,Zinc finger protein 226,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN226_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137888_c2_seq4,683,40.9956,0.52734488,3,16,,7.00E-36,Q8BIA4,F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8),F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8),GO:0031467; GO:0005794; GO:0007030; GO:0019005; GO:0060716; GO:0048471; GO:0050775; GO:0060712; GO:0006511,Cul7-RING ubiquitin ligase complex; Golgi apparatus; Golgi organization; SCF ubiquitin ligase complex; labyrinthine layer blood vessel development; perinuclear region of cytoplasm; positive regulation of dendrite morphogenesis; spongiotrophoblast layer development; ubiquitin-dependent protein catabolic process,PF12937;,6.00E-11,CHOYP_LOC100371688.1.1,,,,,,,FBXW8_MOUSE,Mus musculus (Mouse),cell proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712]; ubiquitin-dependent protein catabolic process [GO:0006511] comp137888_c2_seq6,1314,40.411,0.48565369,3,47,,2.00E-08,A8PTE4,Mitochondrial division protein 1,Mitochondrial division protein 1,GO:0005741,mitochondrial outer membrane,PF00400;,,,,,,,,,MDV1_MALGO,Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus), comp137891_c0_seq2,923,34.7779,0.54310409,8,38,,,,,,,,,,,1.00E-12,ruditapes_c2458,,,,,,, comp137894_c0_seq2,2471,38.3246,0.35385062,7,17,,1.00E-20,O75373,Zinc finger protein 737 (Zinc finger protein 102),Zinc finger protein 737 (Zinc finger protein 102),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,2.00E-16,CHOYP_ZN341.1.1,,,,,,,ZN737_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137894_c0_seq4,2522,38.3029,0.33609215,1,3,,1.00E-35,Q9BYN7,Zinc finger protein 341,Zinc finger protein 341,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,2.00E-16,CHOYP_ZN341.1.1,,,,,,,ZN341_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137898_c0_seq1,4190,40.6921,0.48202856,413,2825,,,,,,,,,2.00E-65,CHOYP_CAPR1.1.1,,,,,,,,, comp137898_c0_seq2,4287,40.3312,0.48536596,1110,15188,,2.00E-46,Q60865,Caprin-1 (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105),Caprin-1 (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105),GO:0003723; GO:0000932; GO:0010494; GO:0005829; GO:0030425; GO:0017148; GO:0050775; GO:0061003,RNA binding; cytoplasmic mRNA processing body; cytoplasmic stress granule; cytosol; dendrite; negative regulation of translation; positive regulation of dendrite morphogenesis; positive regulation of dendritic spine morphogenesis,PF12287;,2.00E-65,CHOYP_CAPR1.1.1,,,,,,,CAPR1_MOUSE,Mus musculus (Mouse),negative regulation of translation [GO:0017148]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003] comp137901_c0_seq1,680,48.2353,0.93647067,500,2497,,1.00E-18,Q8VYA5,Serine/arginine-rich splicing factor RS2Z33 (RS-containing zinc finger protein 33) (At-RS2Z33) (At-RSZ33),Serine/arginine-rich splicing factor RS2Z33 (RS-containing zinc finger protein 33) (At-RS2Z33) (At-RSZ33) (AtRSZ33),GO:0016607; GO:0003676; GO:0000166; GO:0000245; GO:0008270,nuclear speck; nucleic acid binding; nucleotide binding; spliceosomal complex assembly; zinc ion binding,PF00076;PF00098;,8.00E-41,CHOYP_LOC100376908.1.4,,,,,,,RSZ33_ARATH,Arabidopsis thaliana (Mouse-ear cress),"mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]" comp137903_c0_seq1,1924,32.3285,0.70228398,11,51,,1.00E-40,P61244,Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X),Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X),GO:0071339; GO:0016605; GO:0071375; GO:0009267; GO:0005737; GO:0030425; GO:0010629; GO:0051402; GO:0006461; GO:0048678; GO:0032868; GO:0060041; GO:0043565; GO:0003700; GO:0003713; GO:0006366,MLL1 complex; PML body; cellular response to peptide hormone stimulus; cellular response to starvation; cytoplasm; dendrite; negative regulation of gene expression; neuron apoptotic process; protein complex assembly; response to axon injury; response to insulin stimulus; retina development in camera-type eye; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription from RNA polymerase II promoter,PF00010;,,,,,,,,,MAX_HUMAN,Homo sapiens (Human),cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; negative regulation of gene expression [GO:0010629]; neuron apoptotic process [GO:0051402]; protein complex assembly [GO:0006461]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription from RNA polymerase II promoter [GO:0006366] comp137903_c0_seq2,1486,33.3782,0.82979948,2,0,,5.00E-41,P61244,Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X),Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X),GO:0071339; GO:0016605; GO:0071375; GO:0009267; GO:0005737; GO:0030425; GO:0010629; GO:0051402; GO:0006461; GO:0048678; GO:0032868; GO:0060041; GO:0043565; GO:0003700; GO:0003713; GO:0006366,MLL1 complex; PML body; cellular response to peptide hormone stimulus; cellular response to starvation; cytoplasm; dendrite; negative regulation of gene expression; neuron apoptotic process; protein complex assembly; response to axon injury; response to insulin stimulus; retina development in camera-type eye; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription from RNA polymerase II promoter,PF00010;,2.00E-39,CHOYP_LOC664267.1.1,,,,,,,MAX_HUMAN,Homo sapiens (Human),cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; negative regulation of gene expression [GO:0010629]; neuron apoptotic process [GO:0051402]; protein complex assembly [GO:0006461]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription from RNA polymerase II promoter [GO:0006366] comp137908_c0_seq1,569,39.3673,0.54742066,5,0,,1.00E-27,E1C213,Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37),Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37),GO:0000082; GO:0051301; GO:0004197; GO:0007067; GO:0035871; GO:0071108; GO:0004221; GO:0006511; GO:0004843,G1/S transition of mitotic cell cycle; cell division; cysteine-type endopeptidase activity; mitosis; protein K11-linked deubiquitination; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;PF16674;PF02809;,7.00E-22,CHOYP_UBP37.1.1,,,,,,,UBP37_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511] comp137908_c0_seq4,963,36.7601,0.46208467,0,0,,2.00E-07,Q3KR59,Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10),Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10),GO:0030330; GO:0006281; GO:0006914; GO:0004197; GO:0005769; GO:0045111; GO:0044325; GO:0005634; GO:0002039; GO:0016579; GO:0010506; GO:0004221; GO:0006511; GO:0004843,"DNA damage response, signal transduction by p53 class mediator; DNA repair; autophagy; cysteine-type endopeptidase activity; early endosome; intermediate filament cytoskeleton; ion channel binding; nucleus; p53 binding; protein deubiquitination; regulation of autophagy; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity",PF07145;PF00443;,,,,,,,,,UBP10_RAT,Rattus norvegicus (Rat),"autophagy [GO:0006914]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp137912_c0_seq1,1817,39.4606,0.29983046,4,21,,5.00E-29,Q6IN84,"rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial large ribosomal RNA ribose methylase)","rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1145)-2'-O)-methyltransferase) (16S rRNA [Gm1145] 2'-O-methyltransferase)",GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0005739,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; mitochondrion,PF00588;PF08032;,,,,,,,,,MRM1_HUMAN,Homo sapiens (Human),enzyme-directed rRNA 2'-O-methylation [GO:0000453] comp137912_c0_seq3,1762,39.7843,0.30382094,19,13,,1.00E-20,B1MGY6,Uncharacterized tRNA/rRNA methyltransferase MAB_0572 (EC 2.1.1.-),Uncharacterized tRNA/rRNA methyltransferase MAB_0572 (EC 2.1.1.-),GO:0003723; GO:0001510; GO:0008173; GO:0006396,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing,PF00588;PF08032;,,,,,,,,,Y572_MYCA9,Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543),RNA processing [GO:0006396] comp137912_c0_seq4,1223,38.7572,0.33373952,0,0,,2.00E-16,Q76NT0,Mitochondrial rRNA methyltransferase (EC 2.1.1.-) (Mitochondrial large ribosomal RNA ribose methylase),"rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (rRNA (guanosine-2'-O)-methyltransferase)",GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0005739,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; mitochondrion,PF00588;PF08032;,,,,,,,,,MRM1_DICDI,Dictyostelium discoideum (Slime mold),enzyme-directed rRNA 2'-O-methylation [GO:0000453] comp137916_c0_seq1,2474,37.1059,0.48571929,64,584,,7.00E-94,Q149F1,RNA pseudouridylate synthase domain-containing protein 2,RNA pseudouridylate synthase domain-containing protein 2,GO:0003723; GO:0009982; GO:0001522,RNA binding; pseudouridine synthase activity; pseudouridine synthesis,PF00849;,2.00E-18,CHOYP_DVIR_GJ14588.1.1,,,,,,,RUSD2_MOUSE,Mus musculus (Mouse),tRNA pseudouridine synthesis [GO:0031119] comp137917_c1_seq1,1547,40.5301,0.47367475,38,306,,5.00E-54,Q54BM3,Mitochondrial substrate carrier family protein G (Solute carrier family 25 member 20 homolog A),Mitochondrial substrate carrier family protein G (Solute carrier family 25 member 20 homolog A),GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,,,,,,,,,MCFG_DICDI,Dictyostelium discoideum (Slime mold),translation [GO:0006412]; transport [GO:0006810] comp137917_c1_seq2,1532,40.5352,0.46227533,56,197,,8.00E-135,O43772,Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20),Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20),GO:0006853; GO:0044255; GO:0016021; GO:0005743; GO:0044281,carnitine shuttle; cellular lipid metabolic process; integral to membrane; mitochondrial inner membrane; small molecule metabolic process,PF00153;,4.00E-156,CHOYP_ISCW_ISCW022609.1.1,3.00E-42,ruditapes_c15870,,,,,MCAT_HUMAN,Homo sapiens (Human),carnitine shuttle [GO:0006853]; translation [GO:0006412] comp137919_c1_seq1,1660,37.2289,0.44757876,134,684,,2.00E-85,Q6DFS6,Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a),Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a),GO:0031902; GO:0015031,late endosome membrane; protein transport,PF03357;,4.00E-113,CHOYP_CHM2A.1.1,,,,,,,CHM2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),exit from mitosis [GO:0010458]; nuclear envelope reassembly [GO:0031468]; protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp137921_c0_seq1,2852,38.8499,0.65446081,0,6,,,,,,,,,1.00E-38,CHOYP_KAT6B.2.2,,,,,,,,, comp137921_c0_seq2,3083,39.0529,0.64322369,60,161,,0,Q810T5,"Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)","Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)",GO:0006260; GO:0043966; GO:0043983; GO:0043981; GO:0043982; GO:0004402; GO:0000123; GO:0003700; GO:0006351; GO:0008270,"DNA replication; histone H3 acetylation; histone H4-K12 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity; histone acetyltransferase complex; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01853;PF01530;,0,CHOYP_KAT7.1.1,,,,,,,KAT7_RAT,Rattus norvegicus (Rat),"DNA replication [GO:0006260]; histone H3 acetylation [GO:0043966]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; transcription, DNA-templated [GO:0006351]" comp137927_c0_seq1,1859,41.7429,0.4642473,153,891,,0,Q96BP3,Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) (Spliceosome-associated cyclophilin),Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) (Spliceosome-associated cyclophilin),GO:0071013; GO:0000398; GO:0003755; GO:0006457; GO:0000413,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization",PF00160;PF00400;,0,CHOYP_PPWD1.1.1,,,4.00E-76,AM869337.p.cg.6,8,male gonad,PPWD1_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]" comp137929_c0_seq1,1324,35.0453,0.62976518,3164,14015,,2.00E-57,P62323,Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3),Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3),GO:0008380; GO:0071208; GO:0006397; GO:0005634; GO:0030529,RNA splicing; histone pre-mRNA DCP binding; mRNA processing; nucleus; ribonucleoprotein complex,PF01423;,4.00E-93,CHOYP_LOC100115467.1.1,8.00E-99,ruditapes_c2307,9.00E-92,AM854229.p.cg.6,9,,SMD3_XENLA,Xenopus laevis (African clawed frog),spliceosomal snRNP assembly [GO:0000387] comp137930_c0_seq1,2203,33.9083,0.49714778,784,2871,,2.00E-74,Q5PQ71,"Isochorismatase domain-containing protein 2, mitochondrial",Isochorismatase domain-containing protein 2,GO:0003824; GO:0005739,catalytic activity; mitochondrion,PF00857;,2.00E-17,CHOYP_DDX23.1.1,1.00E-98,ruditapes2_c1617,,,,,ISOC2_XENLA,Xenopus laevis (African clawed frog),metabolic process [GO:0008152] comp137936_c1_seq3,1715,40.8163,1.08680037,802,317,,2.00E-08,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp137936_c1_seq5,820,43.1707,1.10491064,0,9,,3.00E-08,Q61398,Procollagen C-endopeptidase enhancer 1 (P14) (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I procollagen COOH-terminal proteinase enhancer),Procollagen C-endopeptidase enhancer 1 (P14) (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I procollagen COOH-terminal proteinase enhancer),GO:0005518; GO:0031012; GO:0005615; GO:0070062; GO:0008201; GO:0016504; GO:0006508,collagen binding; extracellular matrix; extracellular space; extracellular vesicular exosome; heparin binding; peptidase activator activity; proteolysis,PF00431;PF01759;,,,,,,,,,PCOC1_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp137938_c1_seq1,639,37.5587,0.62222375,72,492,,,,,,,,,2.00E-16,CHOYP_contig_048870,,,,,,,,, comp137940_c0_seq1,4834,37.7741,0.64361818,276,165,,2.00E-95,Q02225,Ski oncogene (Proto-oncogene c-Ski),Ski oncogene (Proto-oncogene c-Ski),GO:0000166; GO:0005634,nucleotide binding; nucleus,PF08782;PF02437;,1.00E-67,CHOYP_SKI.1.1,,,,,,,SKI_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp137941_c1_seq1,269,50.9294,0.75484914,3,21,,2.00E-23,Q17LW0,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,4.00E-14,CHOYP_MYO7A.3.3,,,,,,,MYO7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp137946_c0_seq1,633,41.7062,0.56783041,31,109,,2.00E-17,O23755,Elongation factor 2 (EF-2),Elongation factor 2 (EF-2),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,1.00E-63,CHOYP_EFTUD1.1.1,,,,,,,EF2_BETVU,Beta vulgaris (Sugar beet), comp137946_c0_seq2,1519,39.8947,0.56788359,81,499,,2.00E-114,Q8C0D5,Elongation factor Tu GTP-binding domain-containing protein 1,Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A),GO:0005525; GO:0003924; GO:0042256; GO:0043022; GO:0003746,GTP binding; GTPase activity; mature ribosome assembly; ribosome binding; translation elongation factor activity,PF00679;PF14492;,2.00E-66,CHOYP_EFTUD1.1.1,1.00E-40,ruditapes_c31249,,,,,ETUD1_MOUSE,Mus musculus (Mouse),mature ribosome assembly [GO:0042256] comp137958_c2_seq1,487,41.8891,0.7060215,8,54,,4.00E-14,Q60439,Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1),Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1),GO:0007050; GO:0004861; GO:0005768; GO:0006469; GO:0005634,cell cycle arrest; cyclin-dependent protein serine/threonine kinase inhibitor activity; endosome; negative regulation of protein kinase activity; nucleus,PF02234;,,,,,,,,,CDN1B_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),cell cycle arrest [GO:0007050]; regulation of cell proliferation [GO:0042127] comp137959_c0_seq2,1299,38.1062,0.38870455,5,42,,1.00E-21,Q9UIF7,A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH),Adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH),GO:0051539; GO:0032407; GO:0045007; GO:0016798; GO:0046872; GO:0006298; GO:0005739; GO:0005654,"4 iron, 4 sulfur cluster binding; MutSalpha complex binding; depurination; hydrolase activity, acting on glycosyl bonds; metal ion binding; mismatch repair; mitochondrion; nucleoplasm",PF00633;PF00730;PF14815;,,,,,,,,,MUTYH_HUMAN,Homo sapiens (Human),depurination [GO:0045007]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; response to oxidative stress [GO:0006979] comp137961_c2_seq1,1116,37.8136,0.42790218,14,61,,4.00E-76,Q29L80,PITH domain-containing protein GA19395,PITH domain-containing protein GA19395,,,PF06201;,1.00E-35,CHOYP_LOC100890512.1.1,,,,,,,PITH1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp137961_c2_seq3,2997,32.4658,0.50795916,9091,344,,9.00E-115,Q9DAK2,Parkin coregulated gene protein homolog (Hypertension-related protein 1-like protein) (PARK2 coregulated gene protein),Parkin coregulated gene protein homolog (Hypertension-related protein 1-like protein) (PARK2 coregulated gene protein),GO:0044297; GO:0005739; GO:0097225; GO:0007286,cell body; mitochondrion; sperm midpiece; spermatid development,PF10274;,4.00E-160,CHOYP_BRAFLDRAFT_99083.1.1,,,2.00E-159,AM855102.p.cg.6,5,,PACRG_MOUSE,Mus musculus (Mouse),cellular response to unfolded protein [GO:0034620]; negative regulation of cell death [GO:0060548]; spermatid development [GO:0007286] comp137961_c2_seq5,1282,37.2855,0.36142776,9,31,,2.00E-75,Q29L80,PITH domain-containing protein GA19395,PITH domain-containing protein GA19395,,,PF06201;,3.00E-18,CHOYP_LOC100176678.1.1,,,,,,,PITH1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp137965_c0_seq1,2389,38.8866,0.57056924,150,68,,0,Q9JIM0,Double-strand break repair protein MRE11A (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A),Double-strand break repair protein MRE11A (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A),GO:0030870; GO:0000794; GO:0006302; GO:0004519; GO:0004527; GO:0007507; GO:0030145; GO:0000790; GO:0090305; GO:0005654; GO:0048471; GO:0007131; GO:0000723,Mre11 complex; condensed nuclear chromosome; double-strand break repair; endonuclease activity; exonuclease activity; heart development; manganese ion binding; nuclear chromatin; nucleic acid phosphodiester bond hydrolysis; nucleoplasm; perinuclear region of cytoplasm; reciprocal meiotic recombination; telomere maintenance,PF00149;PF04152;,4.00E-178,CHOYP_MRE11.2.2,,,,,,,MRE11_RAT,Rattus norvegicus (Rat),double-strand break repair [GO:0006302]; heart development [GO:0007507]; intra-S DNA damage checkpoint [GO:0031573]; meiotic cell cycle [GO:0051321]; negative regulation of viral entry into host cell [GO:0046597] comp137967_c1_seq6,1139,38.7182,0.39934092,0,0,,1.00E-24,Q96MB7,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_HUMAN,Homo sapiens (Human), comp137967_c1_seq8,1120,38.8393,0.40332307,2,0,,2.00E-23,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp137968_c0_seq1,1914,31.6614,0.60754428,876,5969,,,,,,,,,,,6.00E-14,ruditapes_c23028,,,,,,, comp137970_c0_seq2,2059,43.2734,0.56637457,113,212,,0,Q9H9B1,Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D),Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D),GO:0006306; GO:0005694; GO:0009790; GO:0046976; GO:0046974; GO:0000122; GO:0045892; GO:0005634; GO:0018027; GO:0018026; GO:0008270,"DNA methylation; chromosome; embryo development; histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleus; peptidyl-lysine dimethylation; peptidyl-lysine monomethylation; zinc ion binding",PF12796;PF05033;PF00856;,5.00E-144,CHOYP_EHMT2.1.1,,,,,,,EHMT1_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; DNA methylation [GO:0006306]; embryo development [GO:0009790]; histone methylation [GO:0016571]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]" comp137971_c0_seq1,419,44.8687,0.29872147,10,10,,2.00E-10,Q5RFE9,Leucine-rich repeat-containing protein 40,Leucine-rich repeat-containing protein 40,,,PF12799;PF13855;,,,,,,,,,LRC40_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp137971_c0_seq3,1197,41.1863,0.62188582,3,0,,4.00E-17,P14885,Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (Fragment),Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (Fragment),GO:0051693; GO:0060271; GO:0005737; GO:0005856; GO:0046872,actin filament capping; cilium morphogenesis; cytoplasm; cytoskeleton; metal ion binding,PF00626;,,,,,,,,,GELS_XENLA,Xenopus laevis (African clawed frog),actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium morphogenesis [GO:0060271] comp137971_c0_seq4,2552,42.5157,0.59210254,102,123,,0,Q24020,Protein flightless-1 (Flightless-I),Protein flightless-1 (Flightless-I),GO:0003779; GO:0007527; GO:0007629; GO:0010004; GO:0030239,actin binding; adult somatic muscle development; flight behavior; gastrulation involving germ band extension; myofibril assembly,PF00626;PF00560;PF13855;,0,CHOYP_LOC656702.1.1,,,,,,,FLII_DROME,Drosophila melanogaster (Fruit fly),actin filament severing [GO:0051014]; adult somatic muscle development [GO:0007527]; flight behavior [GO:0007629]; gastrulation involving germ band extension [GO:0010004]; myofibril assembly [GO:0030239] comp137972_c4_seq1,679,33.2842,0.58745121,82,355,,,,,,,,,,,9.00E-13,ruditapes2_c1288,,,,,,, comp137973_c1_seq3,971,45.6231,0.46178682,9,91,,7.00E-122,Q9H269,Vacuolar protein sorting-associated protein 16 homolog (hVPS16),Vacuolar protein sorting-associated protein 16 homolog (hVPS16),GO:0030897; GO:0005884; GO:0030424; GO:0005769; GO:0006886; GO:0005770; GO:0031902; GO:0005765; GO:0043025; GO:0055037,HOPS complex; actin filament; axon; early endosome; intracellular protein transport; late endosome; late endosome membrane; lysosomal membrane; neuronal cell body; recycling endosome,PF04840;PF04841;,5.00E-90,CHOYP_BRAFLDRAFT_105238.1.1,,,,,,,VPS16_HUMAN,Homo sapiens (Human),"autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]" comp137974_c0_seq1,716,42.1788,0.44119284,0,2,,6.00E-26,Q8WXR4,Myosin-IIIb (EC 2.7.11.1),Myosin-IIIb (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0032433; GO:0000146; GO:0016459; GO:0018105; GO:0018107; GO:0001917; GO:0001750; GO:0051491; GO:0046777; GO:0004674; GO:0050896; GO:0032426; GO:0007601,ATP binding; cytoplasm; filopodium tip; microfilament motor activity; myosin complex; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; photoreceptor inner segment; photoreceptor outer segment; positive regulation of filopodium assembly; protein autophosphorylation; protein serine/threonine kinase activity; response to stimulus; stereocilium bundle tip; visual perception,PF00612;PF00063;PF00069;,,,,,,,,,MYO3B_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp137974_c0_seq2,759,41.7655,0.45382244,0,12,,3.00E-31,Q8NEV4,Myosin-IIIa (EC 2.7.11.1),Myosin-IIIa (EC 2.7.11.1),GO:0043531; GO:0005524; GO:0030898; GO:0005516; GO:0005737; GO:0031941; GO:0030175; GO:0032433; GO:0048839; GO:0016459; GO:0018105; GO:0018107; GO:0001917; GO:0060002; GO:0051491; GO:0046777; GO:0004672; GO:0004674; GO:0050896; GO:0007605; GO:0032426; GO:0007601,ADP binding; ATP binding; actin-dependent ATPase activity; calmodulin binding; cytoplasm; filamentous actin; filopodium; filopodium tip; inner ear development; myosin complex; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; photoreceptor inner segment; plus-end directed microfilament motor activity; positive regulation of filopodium assembly; protein autophosphorylation; protein kinase activity; protein serine/threonine kinase activity; response to stimulus; sensory perception of sound; stereocilium bundle tip; visual perception,PF00612;PF00063;PF00069;,,,,,,,,,MYO3A_HUMAN,Homo sapiens (Human),protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp137974_c1_seq1,2772,37.5902,0.57762245,76,1359,,3.00E-08,P45897,Dwarfin sma-4 (MAD protein homolog 3),Dwarfin sma-4 (MAD protein homolog 3),GO:0003677; GO:0005737; GO:0040024; GO:0046872; GO:0005634; GO:0045793; GO:0040018; GO:0046622; GO:0045732; GO:0003700; GO:0045138; GO:0005667; GO:0006351; GO:0007179,"DNA binding; cytoplasm; dauer larval development; metal ion binding; nucleus; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; positive regulation of protein catabolic process; sequence-specific DNA binding transcription factor activity; tail tip morphogenesis; transcription factor complex; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway",PF03165;PF03166;,,,,,,,,,SMA4_CAEEL,Caenorhabditis elegans,"dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; parturition [GO:0007567]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp137974_c2_seq1,867,44.06,0.51144849,7,105,,3.00E-53,Q8WXR4,Myosin-IIIb (EC 2.7.11.1),Myosin-IIIb (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0032433; GO:0000146; GO:0016459; GO:0018105; GO:0018107; GO:0001917; GO:0001750; GO:0051491; GO:0046777; GO:0004674; GO:0050896; GO:0032426; GO:0007601,ATP binding; cytoplasm; filopodium tip; microfilament motor activity; myosin complex; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; photoreceptor inner segment; photoreceptor outer segment; positive regulation of filopodium assembly; protein autophosphorylation; protein serine/threonine kinase activity; response to stimulus; stereocilium bundle tip; visual perception,PF00612;PF00063;PF00069;,,,,,,,,,MYO3B_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp137976_c0_seq1,2251,43.8916,0.50004327,0,0,,0,Q5T5C0,Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1),Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1),GO:0005892; GO:0030054; GO:0030659; GO:0006887; GO:0045921; GO:0015031; GO:0008021; GO:0017075,acetylcholine-gated channel complex; cell junction; cytoplasmic vesicle membrane; exocytosis; positive regulation of exocytosis; protein transport; synaptic vesicle; syntaxin-1 binding,PF08596;PF08366;PF00400;,0,CHOYP_STXB5.1.2,,,,,,,STXB5_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of blood coagulation [GO:0030193]; regulation of exocytosis [GO:0017157]; regulation of gene expression [GO:0010468]; regulation of protein secretion [GO:0050708] comp137976_c0_seq10,2292,43.8482,0.46484173,0,0,,0,Q9Y2K9,Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),GO:0005737; GO:0006887; GO:0042593; GO:0016021; GO:0046676; GO:0005886; GO:0015031; GO:0017157,cytoplasm; exocytosis; glucose homeostasis; integral to membrane; negative regulation of insulin secretion; plasma membrane; protein transport; regulation of exocytosis,PF08596;PF08366;PF00400;,,,,,,,,,STB5L_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708] comp137976_c0_seq14,2375,43.6211,0.46200798,0,0,,4.00E-66,Q8K4K5,Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1),Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1),GO:0000137; GO:0000139; GO:0006893; GO:0005097; GO:0030424; GO:0007409; GO:0005856; GO:0031901; GO:0006887; GO:0032588,Golgi cis cisterna; Golgi membrane; Golgi to plasma membrane transport; Rab GTPase activator activity; axon; axonogenesis; cytoskeleton; early endosome membrane; exocytosis; trans-Golgi network membrane,PF08596;PF08366;,,,,,,,,,L2GL1_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] comp137976_c0_seq17,2525,43.6832,0.51743491,0,0,,0,Q9Y2K9,Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),GO:0005737; GO:0006887; GO:0042593; GO:0016021; GO:0046676; GO:0005886; GO:0015031; GO:0017157,cytoplasm; exocytosis; glucose homeostasis; integral to membrane; negative regulation of insulin secretion; plasma membrane; protein transport; regulation of exocytosis,PF08596;PF08366;PF00400;,0,CHOYP_STXB5.1.2,,,,,,,STB5L_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708] comp137976_c0_seq19,2564,43.4477,0.51498526,0,0,,0,Q5T5C0,Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1),Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1),GO:0005892; GO:0030054; GO:0030659; GO:0006887; GO:0045921; GO:0015031; GO:0008021; GO:0017075,acetylcholine-gated channel complex; cell junction; cytoplasmic vesicle membrane; exocytosis; positive regulation of exocytosis; protein transport; synaptic vesicle; syntaxin-1 binding,PF08596;PF08366;PF00400;,,,,,,,,,STXB5_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of blood coagulation [GO:0030193]; regulation of exocytosis [GO:0017157]; regulation of gene expression [GO:0010468]; regulation of protein secretion [GO:0050708] comp137976_c0_seq20,2545,43.6149,0.52331462,0,0,,2.00E-67,Q8K4K5,Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1),Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1),GO:0000137; GO:0000139; GO:0006893; GO:0005097; GO:0030424; GO:0007409; GO:0005856; GO:0031901; GO:0006887; GO:0032588,Golgi cis cisterna; Golgi membrane; Golgi to plasma membrane transport; Rab GTPase activator activity; axon; axonogenesis; cytoskeleton; early endosome membrane; exocytosis; trans-Golgi network membrane,PF08596;PF08366;,0,CHOYP_STXB5.2.2,,,,,,,L2GL1_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] comp137976_c0_seq22,2331,43.5864,0.46247539,0,0,,1.00E-63,Q80Y17,Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl),Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl),GO:0000137; GO:0000139; GO:0006893; GO:0005097; GO:0030424; GO:0007409; GO:0007420; GO:0030864; GO:0030866; GO:0005856; GO:0031901; GO:0006887; GO:0035090; GO:0035748; GO:0006461; GO:0032588,Golgi cis cisterna; Golgi membrane; Golgi to plasma membrane transport; Rab GTPase activator activity; axon; axonogenesis; brain development; cortical actin cytoskeleton; cortical actin cytoskeleton organization; cytoskeleton; early endosome membrane; exocytosis; maintenance of apical/basal cell polarity; myelin sheath abaxonal region; protein complex assembly; trans-Golgi network membrane,PF08596;PF08366;,,,,,,,,,L2GL1_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; brain development [GO:0007420]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; maintenance of apical/basal cell polarity [GO:0035090]; neurogenesis [GO:0022008]; protein complex assembly [GO:0006461]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] comp137976_c0_seq24,2569,43.7135,0.51596566,0,0,,0,Q9Y2K9,Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),GO:0005737; GO:0006887; GO:0042593; GO:0016021; GO:0046676; GO:0005886; GO:0015031; GO:0017157,cytoplasm; exocytosis; glucose homeostasis; integral to membrane; negative regulation of insulin secretion; plasma membrane; protein transport; regulation of exocytosis,PF08596;PF08366;PF00400;,0,CHOYP_STXB5.1.2,,,,,,,STB5L_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708] comp137976_c0_seq3,2608,43.4816,0.51357473,0,0,,0,Q9Y2K9,Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2),GO:0005737; GO:0006887; GO:0042593; GO:0016021; GO:0046676; GO:0005886; GO:0015031; GO:0017157,cytoplasm; exocytosis; glucose homeostasis; integral to membrane; negative regulation of insulin secretion; plasma membrane; protein transport; regulation of exocytosis,PF08596;PF08366;PF00400;,0,CHOYP_STXB5.2.2,,,,,,,STB5L_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708] comp137976_c0_seq6,2018,44.1031,0.43939297,0,0,,2.00E-64,Q80Y17,Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl),Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl),GO:0000137; GO:0000139; GO:0006893; GO:0005097; GO:0030424; GO:0007409; GO:0007420; GO:0030864; GO:0030866; GO:0005856; GO:0031901; GO:0006887; GO:0035090; GO:0035748; GO:0006461; GO:0032588,Golgi cis cisterna; Golgi membrane; Golgi to plasma membrane transport; Rab GTPase activator activity; axon; axonogenesis; brain development; cortical actin cytoskeleton; cortical actin cytoskeleton organization; cytoskeleton; early endosome membrane; exocytosis; maintenance of apical/basal cell polarity; myelin sheath abaxonal region; protein complex assembly; trans-Golgi network membrane,PF08596;PF08366;,,,,,,,,,L2GL1_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; brain development [GO:0007420]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; maintenance of apical/basal cell polarity [GO:0035090]; neurogenesis [GO:0022008]; protein complex assembly [GO:0006461]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] comp137976_c0_seq7,2501,43.5826,0.52494729,0,0,,0,Q5T5C0,Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1),Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1),GO:0005892; GO:0030054; GO:0030659; GO:0006887; GO:0045921; GO:0015031; GO:0008021; GO:0017075,acetylcholine-gated channel complex; cell junction; cytoplasmic vesicle membrane; exocytosis; positive regulation of exocytosis; protein transport; synaptic vesicle; syntaxin-1 binding,PF08596;PF08366;PF00400;,0,CHOYP_STXB5.1.2,,,,,,,STXB5_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of blood coagulation [GO:0030193]; regulation of exocytosis [GO:0017157]; regulation of gene expression [GO:0010468]; regulation of protein secretion [GO:0050708] comp137976_c0_seq9,2336,43.8784,0.46431773,0,0,,3.00E-58,Q08470,Protein lethal(2) giant larvae (p127),Protein lethal(2) giant larvae (p127),GO:0007049; GO:0006887; GO:0005886; GO:0005578,cell cycle; exocytosis; plasma membrane; proteinaceous extracellular matrix,PF08366;,,,,,,,,,L2GL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),cell cycle [GO:0007049]; exocytosis [GO:0006887] comp137981_c0_seq1,1417,40.2258,0.55151588,93,298,,7.00E-137,Q5PQR5,U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4),U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4),GO:0005730; GO:0006364; GO:0030529,nucleolus; rRNA processing; ribonucleoprotein complex,PF04427;,5.00E-130,CHOYP_BRAFLDRAFT_279143.1.1,,,,,,,IMP4_RAT,Rattus norvegicus (Rat),rRNA processing [GO:0006364] comp137982_c1_seq1,1210,43.1405,1.03185612,15,116,,6.00E-16,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp137982_c1_seq2,1631,40.5886,1.00930477,104,537,,2.00E-17,P15364,Protein amalgam,Protein amalgam,GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF07679;,,,,,,,,,AMAL_DROME,Drosophila melanogaster (Fruit fly), comp137982_c1_seq3,1597,40.6387,1.02839345,8,46,,2.00E-21,Q24372,Lachesin,Lachesin,GO:0031225; GO:0061343; GO:0007156; GO:0035160; GO:0016331; GO:0005886; GO:0042803; GO:0035151; GO:0005918; GO:0019991,"anchored to membrane; cell adhesion involved in heart morphogenesis; homophilic cell adhesion; maintenance of epithelial integrity, open tracheal system; morphogenesis of embryonic epithelium; plasma membrane; protein homodimerization activity; regulation of tube size, open tracheal system; septate junction; septate junction assembly",PF07679;,,,,,,,,,LACH_DROME,Drosophila melanogaster (Fruit fly),"cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]" comp137985_c0_seq1,2568,42.134,0.35779327,5955,20221,,0,P15690,"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD)","NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD)",GO:0051537; GO:0051539; GO:0046034; GO:0042773; GO:0008137; GO:0008637; GO:0045333; GO:0009055; GO:0046872; GO:0005758; GO:0005747; GO:0072593; GO:0051881,"2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; ATP metabolic process; ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; apoptotic mitochondrial changes; cellular respiration; electron carrier activity; metal ion binding; mitochondrial intermembrane space; mitochondrial respiratory chain complex I; reactive oxygen species metabolic process; regulation of mitochondrial membrane potential",PF00384;PF10588;PF09326;,0,CHOYP_LOC582178.1.1,2.00E-154,ruditapes2_c1582,,,,,NDUS1_BOVIN,Bos taurus (Bovine),apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; ATP synthesis coupled electron transport [GO:0042773]; cellular respiration [GO:0045333]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881] comp137986_c0_seq2,2041,40.9603,0.39758577,0,0,,0,Q7T2A5,Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein),Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity; translational initiation,PF10255;,0,CHOYP_EIF3L.1.1,,,,,,,EIF3L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp137986_c0_seq3,2043,40.9692,0.39700213,0,0,,0,A7SDW5,Eukaryotic translation initiation factor 3 subunit L (eIF3l),Eukaryotic translation initiation factor 3 subunit L (eIF3l),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity,PF10255;,0,CHOYP_EIF3L.1.1,5.00E-110,ruditapes_c21050,,,,,EIF3L_NEMVE,Nematostella vectensis (Starlet sea anemone),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] comp137986_c0_seq4,2065,41.0169,0.40352473,0,0,,0,Q9VTU4,Eukaryotic translation initiation factor 3 subunit L (eIF3l),Eukaryotic translation initiation factor 3 subunit L (eIF3l),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0048812; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; neuron projection morphogenesis; regulation of translational initiation; translation initiation factor activity,PF10255;,,,,,,,,,EIF3L_DROME,Drosophila melanogaster (Fruit fly),formation of translation preinitiation complex [GO:0001731]; neuron projection morphogenesis [GO:0048812]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp137987_c1_seq1,966,36.5424,0.65337908,72,252,,3.00E-07,Q645M6,Protein FADD (FAS-associated death domain protein) (FAS-associating death domain-containing protein),FAS-associated death domain protein (FAS-associating death domain-containing protein) (Protein FADD),GO:0031265; GO:0097202; GO:0071260; GO:0051607; GO:0097191; GO:0045087; GO:0070265; GO:0043123; GO:0043065; GO:2001238; GO:0032757; GO:0045862; GO:0045944; GO:0032760; GO:0060340,CD95 death-inducing signaling complex; activation of cysteine-type endopeptidase activity; cellular response to mechanical stimulus; defense response to virus; extrinsic apoptotic signaling pathway; innate immune response; necrotic cell death; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-8 production; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of type I interferon-mediated signaling pathway,PF00531;PF01335;,,,,,,,,,FADD_BOVIN,Bos taurus (Bovine),"activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; TRAIL-activated apoptotic signaling pathway [GO:0036462]" comp137991_c0_seq1,1847,36.0585,0.57534263,687,540,,9.00E-113,Q2F637,14-3-3 protein zeta,14-3-3 protein zeta,GO:0005737,cytoplasm,PF00244;,1.00E-37,CHOYP_1433Z.1.1,8.00E-44,ruditapes_c9760,,,,,1433Z_BOMMO,Bombyx mori (Silk moth), comp137992_c0_seq1,1242,39.6135,0.45248644,374,1003,,4.00E-98,Q9W107,"Probable tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)","Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Mitochondrial tyrosyl-tRNA synthetase) (Tyrosyl-tRNA synthetase) (TyrRS)",GO:0005524; GO:0003723; GO:0005759; GO:0004831; GO:0006437,ATP binding; RNA binding; mitochondrial matrix; tyrosine-tRNA ligase activity; tyrosyl-tRNA aminoacylation,PF00579;,,,,,,,,,SYYM_DROME,Drosophila melanogaster (Fruit fly),mitochondrial tyrosyl-tRNA aminoacylation [GO:0070184]; tRNA aminoacylation [GO:0043039] comp137993_c1_seq1,997,42.7282,0.50611918,8,108,,,,,,,,,7.00E-25,CHOYP_LOC587346.1.1,,,,,,,,, comp137993_c1_seq2,1119,42.7167,0.54902005,11,152,,8.00E-34,A1A5V9,Elongator complex protein 5 (Dermal papilla-derived protein 6 homolog) (Retinoic acid-induced protein 12),Elongator complex protein 5 (Dermal papilla-derived protein 6 homolog) (Retinoic acid-induced protein 12),GO:0033588; GO:0005737; GO:0005634; GO:0030335; GO:0006355; GO:0006351,"Elongator holoenzyme complex; cytoplasm; nucleus; positive regulation of cell migration; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10483;,,,,,,,,,ELP5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"positive regulation of cell migration [GO:0030335]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp137997_c0_seq1,648,40.2778,0.4970555,106,48,,2.00E-55,P23437,Cyclin-dependent kinase 2 (EC 2.7.11.22) (CDC2 homolog Eg1 protein kinase) (Cell division protein kinase 2),Cyclin-dependent kinase 2 (EC 2.7.11.22) (CDC2 homolog Eg1 protein kinase) (Cell division protein kinase 2),GO:0005524; GO:0051301; GO:0004693; GO:0007067,ATP binding; cell division; cyclin-dependent protein serine/threonine kinase activity; mitosis,PF00069;,,,,,,,,,CDK2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp137997_c1_seq1,675,41.7778,0.68500936,57,47,,4.00E-105,Q63699,Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2),Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2),GO:0005524; GO:0015030; GO:0006281; GO:0051301; GO:0032869; GO:0004693; GO:0005829; GO:0005768; GO:0007126; GO:0046872; GO:0005815; GO:0007067; GO:0005634; GO:0031100; GO:0051591; GO:0046686; GO:0042493; GO:0051602; GO:0032355; GO:0045471; GO:0009636,ATP binding; Cajal body; DNA repair; cell division; cellular response to insulin stimulus; cyclin-dependent protein serine/threonine kinase activity; cytosol; endosome; meiosis; metal ion binding; microtubule organizing center; mitosis; nucleus; organ regeneration; response to cAMP; response to cadmium ion; response to drug; response to electrical stimulus; response to estradiol stimulus; response to ethanol; response to toxic substance,PF00069;,2.00E-99,CHOYP_CDK2.1.1,,,,,,,CDK2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cellular response to insulin stimulus [GO:0032869]; DNA repair [GO:0006281]; lens development in camera-type eye [GO:0002088]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; organ regeneration [GO:0031100]; response to cadmium ion [GO:0046686]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to toxic substance [GO:0009636] comp137998_c0_seq1,1048,47.1374,0.80030251,47,123,,2.00E-66,Q9V0D5,Malate dehydrogenase (EC 1.1.1.37),Malate dehydrogenase (EC 1.1.1.37),GO:0030060; GO:0005737; GO:0006099,L-malate dehydrogenase activity; cytoplasm; tricarboxylic acid cycle,PF02615;,7.00E-63,CHOYP_CRE_02254.1.1,,,,,,,MDH_PYRAB,Pyrococcus abyssi (strain GE5 / Orsay),tricarboxylic acid cycle [GO:0006099] comp137998_c0_seq2,840,46.6667,0.74351111,0,8,,,,,,,,,1.00E-26,CHOYP_LOC101069440.1.3,,,,,,,,, comp138001_c0_seq3,235,41.7021,0.62739284,12,3,,,,,,,,,5.00E-19,CHOYP_LOC101166008.1.1,,,,,,,,, comp138002_c0_seq1,1744,42.8326,0.77554469,7,712,female>male,9.00E-73,Q93YS4,ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23),ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0005886; GO:0009414; GO:0010148,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; plasma membrane; response to water deprivation; transpiration,PF01061;PF00005;,3.00E-20,CHOYP_NEMVEDRAFT_V1G103967.1.1,,,,,,,AB22G_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to water deprivation [GO:0009414]; transpiration [GO:0010148] comp138002_c1_seq1,538,40.7063,0.89998641,0,49,,9.00E-13,Q82WT5,Sulfate/thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) (Sulfate-transporting ATPase),Sulfate/thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) (Sulfate-transporting ATPase),GO:0005524; GO:0006200; GO:0005886; GO:0015419; GO:0008272,ATP binding; ATP catabolic process; plasma membrane; sulfate transmembrane-transporting ATPase activity; sulfate transport,PF00005;PF12857;,,,,,,,,,CYSA_NITEU,Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298), comp138002_c1_seq2,443,40.8578,0.76083619,0,6,,4.00E-08,Q2SPI3,Zinc import ATP-binding protein ZnuC 1 (EC 3.6.3.-),Zinc import ATP-binding protein ZnuC 1 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0005886; GO:0015633,ATP binding; ATP catabolic process; ATPase activity; plasma membrane; zinc transporting ATPase activity,PF00005;,,,,,,,,,ZNUC1_HAHCH,Hahella chejuensis (strain KCTC 2396), comp138003_c0_seq1,1268,39.511,0.52627078,91,94,,2.00E-09,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp138007_c0_seq1,1695,36.5782,0.48676073,209,437,,4.00E-59,P34022,Ran-specific GTPase-activating protein (HpaII tiny fragments locus 9a protein) (Ran-binding protein 1) (RANBP1),Ran-specific GTPase-activating protein (HpaII tiny fragments locus 9a protein) (Ran-binding protein 1) (RANBP1),GO:0005096; GO:0005813; GO:0005737; GO:0046907; GO:0043547; GO:0046604; GO:0007051,GTPase activator activity; centrosome; cytoplasm; intracellular transport; positive regulation of GTPase activity; positive regulation of mitotic centrosome separation; spindle organization,PF00638;,2.00E-53,CHOYP_BRAFLDRAFT_272416.1.1,,,,,,,RANG_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; cellular response to leptomycin B [GO:0072750]; G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of mitotic centrosome separation [GO:0046604]; positive regulation of neuron projection development [GO:0010976]; protein import into nucleus [GO:0006606]; response to calcium ion [GO:0051592]; RNA export from nucleus [GO:0006405]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138010_c1_seq2,777,47.7477,0.43389763,3,0,,3.00E-20,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138012_c0_seq1,2157,41.0292,0.69161676,7,9,,9.00E-166,O55028,"[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)","[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)",GO:0005524; GO:0047323; GO:0009083; GO:0005947; GO:0004674,ATP binding; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; branched-chain amino acid catabolic process; mitochondrial alpha-ketoglutarate dehydrogenase complex; protein serine/threonine kinase activity,PF10436;PF02518;,,,,,,,,,BCKD_MOUSE,Mus musculus (Mouse),branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310] comp138012_c0_seq2,1234,39.222,0.5365836,4,1,,,,,,,,,3.00E-17,CHOYP_BCKD.1.2,,,,,,,,, comp138012_c0_seq5,1118,40.7871,0.82153894,7,9,,,,,,,,,4.00E-34,CHOYP_BCKD.2.2,,,,,,,,, comp138012_c0_seq6,1148,39.9826,0.83184791,0,0,,2.00E-82,O55028,"[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)","[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)",GO:0005524; GO:0047323; GO:0009083; GO:0005947; GO:0004674,ATP binding; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; branched-chain amino acid catabolic process; mitochondrial alpha-ketoglutarate dehydrogenase complex; protein serine/threonine kinase activity,PF10436;PF02518;,,,,,,,,,BCKD_MOUSE,Mus musculus (Mouse),branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310] comp138018_c0_seq1,1672,38.1579,0.61752815,207,565,,5.00E-30,Q8R0W6,NEDD4 family-interacting protein 1 (NEDD4 WW domain-binding protein 5),NEDD4 family-interacting protein 1 (NEDD4 WW domain-binding protein 5),GO:0005938; GO:0006879; GO:0010008; GO:0005576; GO:0030173; GO:0042130; GO:0010629; GO:0050728; GO:0032713; GO:0048294; GO:0051224; GO:0032410; GO:0002829; GO:0048471; GO:0043123; GO:0045732; GO:0031398; GO:0048302; GO:0045619; GO:0002761; GO:0004871; GO:0043162,cell cortex; cellular iron ion homeostasis; endosome membrane; extracellular region; integral to Golgi membrane; negative regulation of T cell proliferation; negative regulation of gene expression; negative regulation of inflammatory response; negative regulation of interleukin-4 production; negative regulation of isotype switching to IgE isotypes; negative regulation of protein transport; negative regulation of transporter activity; negative regulation of type 2 immune response; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein catabolic process; positive regulation of protein ubiquitination; regulation of isotype switching to IgG isotypes; regulation of lymphocyte differentiation; regulation of myeloid leukocyte differentiation; signal transducer activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF10176;,2.00E-14,CHOYP_NDFIP2.1.1,,,,,,,NFIP1_MOUSE,Mus musculus (Mouse),cellular iron ion homeostasis [GO:0006879]; metal ion transport [GO:0030001]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-4 production [GO:0032713]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of protein transport [GO:0051224]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transporter activity [GO:0032410]; negative regulation of type 2 immune response [GO:0002829]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein ubiquitination [GO:0031398]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of lymphocyte differentiation [GO:0045619]; regulation of myeloid leukocyte differentiation [GO:0002761]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vacuolar transport [GO:0007034] comp138021_c0_seq1,1765,37.6771,0.67255471,8,371,,,,,,,,,,,2.00E-45,ruditapes_c10174,,,,,,, comp138021_c0_seq2,639,38.6541,0.67832705,0,63,,,,,,,,,,,3.00E-18,ruditapes_c12775,,,,,,, comp138021_c1_seq1,267,38.9513,0,3,26,,4.00E-11,A2AAJ9,Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),GO:0005524; GO:0031430; GO:0005089; GO:0030154; GO:0007275; GO:0018108; GO:0005543; GO:0004674; GO:0004713; GO:0035023,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; cell differentiation; multicellular organismal development; peptidyl-tyrosine phosphorylation; phospholipid binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of Rho protein signal transduction,PF00041;PF07679;PF00612;PF00069;PF00621;,,,,,,,,,OBSCN_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023] comp138021_c1_seq2,621,38.8084,0.26907063,26,10,,4.00E-09,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp138024_c0_seq2,1665,38.0781,0.37034206,2,11,,9.00E-35,A0KKE6,tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase),tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase),GO:0043828; GO:0070329,tRNA 2-selenouridine synthase activity; tRNA seleno-modification,,,,,,,,,,SELU_AERHH,Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240),tRNA seleno-modification [GO:0070329] comp138024_c0_seq7,1495,38.0602,0.37809302,0,6,,3.00E-35,Q6MK43,tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase),tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase),GO:0043828; GO:0070329,tRNA 2-selenouridine synthase activity; tRNA seleno-modification,PF00581;,,,2.00E-11,ruditapes_c13999,,,,,SELU_BDEBA,Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100),tRNA seleno-modification [GO:0070329] comp138025_c0_seq3,363,41.8733,0.26229707,10,0,,2.00E-10,O48652,(6-4)DNA photolyase (EC 4.1.99.13) (Protein UV repair defective 3),(6-4)DNA photolyase (EC 4.1.99.13) (Protein UV repair defective 3),GO:0003914; GO:0003677; GO:0006281; GO:0000166; GO:0009411,DNA (6-4) photolyase activity; DNA binding; DNA repair; nucleotide binding; response to UV,PF00875;PF03441;,,,,,,,,,UVR3_ARATH,Arabidopsis thaliana (Mouse-ear cress),DNA repair [GO:0006281]; response to UV [GO:0009411] comp138025_c0_seq5,388,42.5258,0.29923276,13,0,,2.00E-16,Q8QG60,Cryptochrome-2,Cryptochrome-2,GO:0003913; GO:0006281; GO:0071949; GO:0005737; GO:0005634; GO:0009881; GO:0018298; GO:0006355; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; FAD binding; cytoplasm; nucleus; photoreceptor activity; protein-chromophore linkage; regulation of transcription, DNA-dependent; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY2_CHICK,Gallus gallus (Chicken),"circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; transcription, DNA-templated [GO:0006351]" comp138028_c0_seq1,1880,43.3511,0.47345781,273,1742,,4.00E-141,Q921I2,Kelch domain-containing protein 4,Kelch domain-containing protein 4,,,PF07646;,2.00E-136,CHOYP_LOC100115776.1.1,,,,,,,KLDC4_MOUSE,Mus musculus (Mouse), comp138035_c0_seq1,1090,44.7706,0.55818998,10,29,,2.00E-123,Q8K370,Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),GO:0003995; GO:0050660; GO:0016787; GO:0005739; GO:0016772,"acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; hydrolase activity; mitochondrion; transferase activity, transferring phosphorus-containing groups",PF00441;PF02770;PF02771;PF01636;PF13419;,3.00E-112,CHOYP_LOC100375888.1.1,,,,,,,ACD10_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp138035_c1_seq2,324,45.3704,0.49808904,5,11,,,,,,,,,2.00E-19,CHOYP_LOC100375888.1.1,,,,,,,,, comp138036_c0_seq1,3208,45.3554,0.42517314,70,39,,0,Q9DE14,Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),GO:0005524; GO:0003677; GO:0006281; GO:0005634; GO:0018105; GO:0004674,ATP binding; DNA binding; DNA repair; nucleus; peptidyl-serine phosphorylation; protein serine/threonine kinase activity,PF02259;PF02260;PF00454;PF08064;,,,,,,,,,ATR_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105] comp138036_c0_seq2,1741,45.089,0.42968805,0,0,,2.00E-44,A2YH41,Serine/threonine-protein kinase ATR (EC 2.7.11.1),Serine/threonine-protein kinase ATR (EC 2.7.11.1),GO:0005524; GO:0006281; GO:0042138; GO:0045132; GO:0032504; GO:0005634; GO:0009506; GO:0004674; GO:0007131; GO:0032204; GO:0010044; GO:0010332; GO:0007062; GO:0007129; GO:0043247; GO:0007004,ATP binding; DNA repair; meiotic DNA double-strand break formation; meiotic chromosome segregation; multicellular organism reproduction; nucleus; plasmodesma; protein serine/threonine kinase activity; reciprocal meiotic recombination; regulation of telomere maintenance; response to aluminum ion; response to gamma radiation; sister chromatid cohesion; synapsis; telomere maintenance in response to DNA damage; telomere maintenance via telomerase,PF02259;PF02260;PF00454;PF08064;,8.00E-71,CHOYP_LOC763088.1.1,,,,,,,ATR_ORYSI,Oryza sativa subsp. indica (Rice),cell cycle [GO:0007049]; DNA repair [GO:0006281] comp138036_c0_seq4,1953,44.3932,0.45751396,16,0,,6.00E-157,Q9JKK8,Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),GO:0005524; GO:0003677; GO:0000077; GO:0006281; GO:0001741; GO:0005654; GO:0004674; GO:0043393,ATP binding; DNA binding; DNA damage checkpoint; DNA repair; XY body; nucleoplasm; protein serine/threonine kinase activity; regulation of protein binding,PF02259;PF02260;PF00454;PF08064;,,,,,,,,,ATR_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; establishment of RNA localization to telomere [GO:0097694]; negative regulation of DNA replication [GO:0008156]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of protein binding [GO:0043393]; replicative senescence [GO:0090399]" comp138037_c0_seq3,1577,35.9543,0.95010199,23,468,,5.00E-65,Q9GV41,Prostaglandin F synthase (EC 1.1.1.188) (Prostaglandin F2-alpha synthase),Prostaglandin F synthase (EC 1.1.1.188) (Prostaglandin F2-alpha synthase),GO:0005737; GO:0000166; GO:0036131; GO:0001516; GO:0047017,cytoplasm; nucleotide binding; prostaglandin D2 11-ketoreductase activity; prostaglandin biosynthetic process; prostaglandin-F synthase activity,PF00248;,,,,,,,,,PGFS_TRYBB,Trypanosoma brucei brucei,D-arabinose catabolic process [GO:0019571]; prostaglandin biosynthetic process [GO:0001516] comp138039_c0_seq9,452,40.9292,0.27236786,0,0,,,,,,,,,3.00E-12,CHOYP_BRAFLDRAFT_108792.4.5,,,,,,,,, comp138040_c1_seq1,1196,40.6355,0.47045487,63,420,,7.00E-35,Q5UCC4,ER membrane protein complex subunit 10 (Hematopoietic signal peptide-containing membrane domain-containing protein 1),ER membrane protein complex subunit 10 (Hematopoietic signal peptide-containing membrane domain-containing protein 1),GO:0072546; GO:0005576,ER membrane protein complex; extracellular region,,6.00E-14,CHOYP_EMC10.1.1,,,,,,,EMC10_HUMAN,Homo sapiens (Human), comp138041_c0_seq1,1499,41.0274,0.22339485,3,7,,2.00E-53,Q810L3,E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein),E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein),GO:0016605; GO:0051301; GO:0007067; GO:0000278; GO:0007093; GO:0000166; GO:0000209; GO:0006511; GO:0004842; GO:0008270,PML body; cell division; mitosis; mitotic cell cycle; mitotic cell cycle checkpoint; nucleotide binding; protein polyubiquitination; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF00498;,1.00E-11,CHOYP_CHFR.1.1,,,,,,,CHFR_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic cell cycle [GO:0000278]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; modification-dependent protein catabolic process [GO:0019941]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138041_c0_seq8,2548,39.9529,0.29769695,50,213,,5.00E-70,A5WW08,E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein),E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein),GO:0016605; GO:0051301; GO:0007067; GO:0007093; GO:0019941; GO:0000166; GO:0000209; GO:0004842; GO:0008270,PML body; cell division; mitosis; mitotic cell cycle checkpoint; modification-dependent protein catabolic process; nucleotide binding; protein polyubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00498;,5.00E-44,CHOYP_CHFR.1.1,,,,,,,CHFR_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; modification-dependent protein catabolic process [GO:0019941]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138045_c0_seq1,729,40.7407,0.43955618,9,74,,4.00E-28,Q9WTY1,Programmed cell death protein 7 (ES18),Programmed cell death protein 7 (ES18),GO:0005689; GO:0006915; GO:0070234; GO:2001235; GO:0051384,U12-type spliceosomal complex; apoptotic process; positive regulation of T cell apoptotic process; positive regulation of apoptotic signaling pathway; response to glucocorticoid stimulus,PF16021;,,,6.00E-22,ruditapes_c10176,,,,,PDCD7_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of T cell apoptotic process [GO:0070234]; response to glucocorticoid [GO:0051384] comp138046_c0_seq2,3358,37.7606,0.46336035,596,1485,,0,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,0,CHOYP_UBR4.1.1,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp138049_c0_seq1,2337,41.7202,0.56707981,3,7,,0,Q6PEI7,CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1),CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1),GO:0044210; GO:0005524; GO:0003883; GO:0006541,'de novo' CTP biosynthetic process; ATP binding; CTP synthase activity; glutamine metabolic process,PF06418;PF00117;,,,,,,,,,PYRG1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541] comp138049_c0_seq3,1266,43.6019,0.51658544,10,10,,0,Q5XHA8,CTP synthase 1-A (EC 6.3.4.2) (CTP synthetase 1-A) (UTP--ammonia ligase 1-A),CTP synthase 1-A (EC 6.3.4.2) (CTP synthetase 1-A) (UTP--ammonia ligase 1-A),GO:0044210; GO:0005524; GO:0003883; GO:0006541,'de novo' CTP biosynthetic process; ATP binding; CTP synthase activity; glutamine metabolic process,PF06418;PF00117;,1.00E-156,CHOYP_PYRG1.1.1,,,,,,,PYG1A_XENLA,Xenopus laevis (African clawed frog),'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541] comp138049_c0_seq5,1199,39.7832,0.62995591,0,8,,4.00E-07,Q93DW6,CTP synthase (EC 6.3.4.2) (CTP synthetase) (UTP--ammonia ligase) (Fragment),CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase) (Fragment),GO:0044210; GO:0005524; GO:0003883; GO:0006541,'de novo' CTP biosynthetic process; ATP binding; CTP synthase activity; glutamine metabolic process,PF00117;,,,,,,,,,PYRG_MYCCC,Mycoplasma capricolum subsp. capripneumoniae,'de novo' CTP biosynthetic process [GO:0044210]; glutamine metabolic process [GO:0006541] comp138051_c0_seq1,419,27.9236,0.61367971,36,43,,3.00E-17,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp138055_c0_seq1,1734,34.1984,0.46344056,174,661,,4.00E-65,Q58D06,WD repeat-containing protein 74,WD repeat-containing protein 74,GO:0016070; GO:0001825; GO:0005730,RNA metabolic process; blastocyst formation; nucleolus,PF00400;,2.00E-15,CHOYP_WDR74.1.1,,,,,,,WDR74_BOVIN,Bos taurus (Bovine),blastocyst formation [GO:0001825]; ribosomal large subunit biogenesis [GO:0042273]; RNA metabolic process [GO:0016070] comp138056_c0_seq1,2240,36.1607,0.38800164,3814,10524,,3.00E-137,P13086,"Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)","Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)",GO:0003878; GO:0019003; GO:0005525; GO:0048037; GO:0005743; GO:0005886; GO:0046982; GO:0006105; GO:0004775; GO:0004776; GO:0045244; GO:0006104; GO:0006099,ATP citrate synthase activity; GDP binding; GTP binding; cofactor binding; mitochondrial inner membrane; plasma membrane; protein heterodimerization activity; succinate metabolic process; succinate-CoA ligase (ADP-forming) activity; succinate-CoA ligase (GDP-forming) activity; succinate-CoA ligase complex (GDP-forming); succinyl-CoA metabolic process; tricarboxylic acid cycle,PF02629;PF00549;,0,CHOYP_BRAFLDRAFT_124275.1.1,,,,,,,SUCA_RAT,Rattus norvegicus (Rat),nucleoside triphosphate biosynthetic process [GO:0009142]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] comp138061_c0_seq1,1606,47.3225,0.41271284,6,15,,0,F1N2W9,DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9),DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9),GO:0005524; GO:0003677; GO:0097362; GO:0000724; GO:0007292; GO:0004386; GO:0005634,ATP binding; DNA binding; MCM8-MCM9 complex; double-strand break repair via homologous recombination; female gamete generation; helicase activity; nucleus,PF00493;,0,CHOYP_MCM9.1.1,,,,,,,MCM9_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; gamete generation [GO:0007276] comp138061_c0_seq2,938,44.5629,0.42092769,0,0,,4.00E-48,Q21902,DNA replication licensing factor mcm-5 (EC 3.6.4.12),DNA replication licensing factor mcm-5 (EC 3.6.4.12),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006270; GO:0042555; GO:0007049; GO:0005634,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication initiation; MCM complex; cell cycle; nucleus,PF00493;PF14551;,2.00E-11,CHOYP_MCM7.1.1,,,,,,,MCM5_CAEEL,Caenorhabditis elegans,cell cycle [GO:0007049]; DNA replication initiation [GO:0006270] comp138061_c0_seq4,965,46.4249,0.46788208,5,0,,,,,,,,,5.00E-115,CHOYP_MCM9.1.1,,,,,,,,, comp138063_c0_seq2,730,33.9726,0.28751283,20,290,,2.00E-57,A4FUY7,Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B),Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B),GO:0030366; GO:0005829; GO:0019008; GO:0005634; GO:0016740,Mo-molybdopterin synthase activity; cytosol; molybdopterin synthase complex; nucleus; transferase activity,PF02391;,3.00E-34,CHOYP_TRIADDRAFT_23075.1.1,,,,,,,MOC2B_BOVIN,Bos taurus (Bovine),molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp138063_c0_seq3,262,40.0763,0.29819029,23,311,,4.00E-11,B6SXF8,Molybdopterin synthase sulfur carrier subunit (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Protein viviparous15) (Sulfur carrier protein MOCS2A),Molybdopterin synthase sulfur carrier subunit (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Protein viviparous15) (Sulfur carrier protein MOCS2A),GO:0006777; GO:0009734; GO:0003824; GO:0005737; GO:0018315; GO:0000166; GO:0006790,Mo-molybdopterin cofactor biosynthetic process; auxin mediated signaling pathway; catalytic activity; cytoplasm; molybdenum incorporation into molybdenum-molybdopterin complex; nucleotide binding; sulfur compound metabolic process,PF02597;,,,,,,,,,MOC2A_MAIZE,Zea mays (Maize),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp138064_c0_seq1,1665,42.8228,0.38374305,88,480,,5.00E-122,A3KG59,Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),GO:0016787,hydrolase activity,PF07687;PF01546;,3.00E-63,CHOYP_P20D2.2.2,,,,,,,P20D2_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268] comp138065_c2_seq1,909,43.8944,0.87637594,25,1,,3.00E-133,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,6.00E-114,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp138065_c5_seq1,217,44.7005,0.75499439,10,11,,4.00E-39,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,,,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp138065_c6_seq1,1272,41.5881,0.6382876,141,359,,3.00E-148,A2RSX7,tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase),tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase),GO:0005506; GO:0016706; GO:0042803; GO:0000049; GO:0031591,"iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; protein homodimerization activity; tRNA binding; wybutosine biosynthetic process",,2.00E-89,CHOYP_BRAFLDRAFT_118314.1.1,,,,,,,TYW5_MOUSE,Mus musculus (Mouse),wybutosine biosynthetic process [GO:0031591] comp138068_c0_seq1,2729,44.192,0.48170854,13,51,,8.00E-29,Q12955,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0043001; GO:0030315; GO:0007411; GO:0043194; GO:0007409; GO:0016323; GO:0045296; GO:0009986; GO:0043034; GO:0014704; GO:0044325; GO:0016328; GO:0005764; GO:0072660; GO:0071709; GO:0000281; GO:0033268; GO:0033270; GO:0010628; GO:1900827; GO:0045838; GO:2000651; GO:0010765; GO:0045211; GO:0030674; GO:0072661; GO:0019228; GO:0043266; GO:0007165; GO:0030507; GO:0014731; GO:0005200; GO:0050808,"Golgi to plasma membrane protein transport; T-tubule; axon guidance; axon initial segment; axonogenesis; basolateral plasma membrane; cadherin binding; cell surface; costamere; intercalated disc; ion channel binding; lateral plasma membrane; lysosome; maintenance of protein location in plasma membrane; membrane assembly; mitotic cytokinesis; node of Ranvier; paranode region of axon; positive regulation of gene expression; positive regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential; positive regulation of membrane potential; positive regulation of sodium ion transmembrane transporter activity; positive regulation of sodium ion transport; postsynaptic membrane; protein binding, bridging; protein targeting to plasma membrane; regulation of action potential in neuron; regulation of potassium ion transport; signal transduction; spectrin binding; spectrin-associated cytoskeleton; structural constituent of cytoskeleton; synapse organization",PF00023;PF12796;PF13606;PF00531;PF00791;,,,,,,,,,ANK3_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] comp138068_c0_seq2,2967,43.849,0.50526322,9,41,,2.00E-74,A5PMU4,Ankyrin repeat and sterile alpha motif domain-containing protein 1B,Ankyrin repeat and sterile alpha motif domain-containing protein 1B,GO:0005737,cytoplasm,PF12796;PF00640;PF00536;PF07647;,,,,,,,,,ANS1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp138070_c1_seq1,1509,38.171,0.36623834,18,379,,1.00E-29,Q9R0A0,Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14),Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14),GO:0016021; GO:0034453; GO:0032091; GO:1901094; GO:0043433; GO:0005778; GO:0036250; GO:0043234; GO:0051260; GO:0016560; GO:0044721; GO:0016561,"integral to membrane; microtubule anchoring; negative regulation of protein binding; negative regulation of protein homotetramerization; negative regulation of sequence-specific DNA binding transcription factor activity; peroxisomal membrane; peroxisome transport along microtubule; protein complex; protein homooligomerization; protein import into peroxisome matrix, docking; protein import into peroxisome matrix, substrate release; protein import into peroxisome matrix, translocation",PF04695;,,,,,,,,,PEX14_MOUSE,Mus musculus (Mouse),"microtubule anchoring [GO:0034453]; negative regulation of protein binding [GO:0032091]; negative regulation of protein homotetramerization [GO:1901094]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; peroxisome transport along microtubule [GO:0036250]; protein complex assembly [GO:0006461]; protein homooligomerization [GO:0051260]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561]" comp138075_c0_seq2,1351,36.9356,0.84544543,1,20,,2.00E-15,P27582,3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Fragments),3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Fragments),GO:0004316; GO:0009507; GO:0006633,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; chloroplast; fatty acid biosynthetic process,,,,4.00E-27,ruditapes_c9589,,,,,FABG6_BRANA,Brassica napus (Rape),fatty acid biosynthetic process [GO:0006633] comp138075_c0_seq3,1542,38.1971,0.81844255,0,26,,1.00E-60,O86034,D-beta-hydroxybutyrate dehydrogenase (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (3-HBDH),D-beta-hydroxybutyrate dehydrogenase (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (3-HBDH),GO:0003858,3-hydroxybutyrate dehydrogenase activity,,3.00E-31,CHOYP_LOC100375141.1.1,,,,,,,BDHA_RHIME,Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti), comp138075_c0_seq4,1602,38.2022,0.79238785,0,22,,,,,,,,,3.00E-31,CHOYP_LOC100375141.1.1,,,,,,,,, comp138077_c0_seq1,1236,36.0841,0.47607793,6,64,,1.00E-24,Q9CQL5,"39S ribosomal protein L18, mitochondrial (L18mt) (MRP-L18)","39S ribosomal protein L18, mitochondrial (L18mt) (MRP-L18)",GO:0008097; GO:0005739; GO:0035928; GO:0005840,5S rRNA binding; mitochondrion; rRNA import into mitochondrion; ribosome,PF00861;,,,2.00E-11,ruditapes_c19025,,,,,RM18_MOUSE,Mus musculus (Mouse),rRNA import into mitochondrion [GO:0035928]; translation [GO:0006412] comp138077_c0_seq2,1396,34.384,0.51189152,47,177,,,,,,,,,,,4.00E-14,ruditapes_c24209,,,,,,, comp138078_c0_seq2,1634,38.0661,0.40570735,20,186,,2.00E-101,Q3TD49,Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-),Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-),GO:0030660; GO:0042500; GO:0010008; GO:0071458; GO:0071556; GO:0005765; GO:0006509; GO:0031293; GO:0005886; GO:0042803; GO:0050776,"Golgi-associated vesicle membrane; aspartic endopeptidase activity, intramembrane cleaving; endosome membrane; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; lysosomal membrane; membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; plasma membrane; protein homodimerization activity; regulation of immune response",PF02225;PF04258;,3.00E-26,CHOYP_SPP2B.1.1,,,,,,,SPP2B_MOUSE,Mus musculus (Mouse),membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; regulation of immune response [GO:0050776]; signal peptide processing [GO:0006465] comp138080_c0_seq1,942,42.8875,0.64944977,100,265,,1.00E-83,Q1JP75,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0005903; GO:0005881; GO:0006006; GO:0016020; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; brush border; cytoplasmic microtubule; glucose metabolic process; membrane; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,6.00E-36,ruditapes_c21814,,,,,DCXR_BOVIN,Bos taurus (Bovine),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp138081_c0_seq1,1287,43.9782,0.47362577,0,0,,3.00E-115,Q15149,Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),GO:0006921; GO:0043034; GO:0005829; GO:0030198; GO:0005925; GO:0030056; GO:0031581; GO:0045111; GO:0042383; GO:0016528; GO:0008307,cellular component disassembly involved in execution phase of apoptosis; costamere; cytosol; extracellular matrix organization; focal adhesion; hemidesmosome; hemidesmosome assembly; intermediate filament cytoskeleton; sarcolemma; sarcoplasm; structural constituent of muscle,PF00307;PF00681;PF03501;,2.00E-19,CHOYP_LOC101163060.1.1,,,,,,,PLEC_HUMAN,Homo sapiens (Human),hemidesmosome assembly [GO:0031581] comp138081_c0_seq11,2313,43.2771,0.50437558,0,0,,4.00E-139,Q15149,Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),GO:0006921; GO:0043034; GO:0005829; GO:0030198; GO:0005925; GO:0030056; GO:0031581; GO:0045111; GO:0042383; GO:0016528; GO:0008307,cellular component disassembly involved in execution phase of apoptosis; costamere; cytosol; extracellular matrix organization; focal adhesion; hemidesmosome; hemidesmosome assembly; intermediate filament cytoskeleton; sarcolemma; sarcoplasm; structural constituent of muscle,PF00307;PF00681;PF03501;,8.00E-149,CHOYP_LOC100118464.1.1,,,,,,,PLEC_HUMAN,Homo sapiens (Human),hemidesmosome assembly [GO:0031581] comp138081_c0_seq16,2809,44.571,0.51501477,0,0,,0,P30427,Plectin (PCN) (PLTN) (Plectin-1),Plectin (PCN) (PLTN) (Plectin-1),GO:0016324; GO:0009925; GO:0043034; GO:0008092; GO:0005856; GO:0030855; GO:0007565; GO:0030056; GO:0031581; GO:0048471; GO:0047485; GO:0007584; GO:0042383; GO:0016528; GO:0005200,apical plasma membrane; basal plasma membrane; costamere; cytoskeletal protein binding; cytoskeleton; epithelial cell differentiation; female pregnancy; hemidesmosome; hemidesmosome assembly; perinuclear region of cytoplasm; protein N-terminus binding; response to nutrient; sarcolemma; sarcoplasm; structural constituent of cytoskeleton,PF00307;PF00681;PF03501;,2.00E-17,CHOYP_LOC100876515.1.2,,,,,,,PLEC_RAT,Rattus norvegicus (Rat),epithelial cell differentiation [GO:0030855]; female pregnancy [GO:0007565]; hemidesmosome assembly [GO:0031581]; response to nutrient [GO:0007584] comp138081_c0_seq17,1743,43.7177,0.45263763,0,0,,2.00E-129,Q9QXS1,Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6),Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6),GO:0043292; GO:0005856; GO:0030056; GO:0031581; GO:0042383,contractile fiber; cytoskeleton; hemidesmosome; hemidesmosome assembly; sarcolemma,PF00307;PF00681;PF03501;,,,,,,,,,PLEC_MOUSE,Mus musculus (Mouse),hemidesmosome assembly [GO:0031581] comp138081_c0_seq18,1857,43.3495,0.53193438,0,0,,8.00E-126,Q15149,Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1),GO:0006921; GO:0043034; GO:0005829; GO:0030198; GO:0005925; GO:0030056; GO:0031581; GO:0045111; GO:0042383; GO:0016528; GO:0008307,cellular component disassembly involved in execution phase of apoptosis; costamere; cytosol; extracellular matrix organization; focal adhesion; hemidesmosome; hemidesmosome assembly; intermediate filament cytoskeleton; sarcolemma; sarcoplasm; structural constituent of muscle,PF00307;PF00681;PF03501;,2.00E-141,CHOYP_LOC100118464.1.1,,,,,,,PLEC_HUMAN,Homo sapiens (Human),hemidesmosome assembly [GO:0031581] comp138081_c0_seq2,2407,43.6228,0.33274188,0,0,,1.00E-08,P15924,Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen),Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen),GO:0034332; GO:0016323; GO:0086069; GO:0016337; GO:0006921; GO:0001533; GO:0030057; GO:0002934; GO:0014704; GO:0005882; GO:0045109; GO:0030216; GO:0005739; GO:0018149; GO:0005886; GO:0030674; GO:0071896; GO:0086091; GO:0086005; GO:0005200; GO:0003223,"adherens junction organization; basolateral plasma membrane; bundle of His cell to Purkinje myocyte communication; cell-cell adhesion; cellular component disassembly involved in execution phase of apoptosis; cornified envelope; desmosome; desmosome organization; intercalated disc; intermediate filament; intermediate filament organization; keratinocyte differentiation; mitochondrion; peptide cross-linking; plasma membrane; protein binding, bridging; protein localization to adherens junction; regulation of heart rate by cardiac conduction; regulation of ventricular cardiac muscle cell action potential; structural constituent of cytoskeleton; ventricular compact myocardium morphogenesis",PF00681;,,,2.00E-83,ruditapes_c7245,,,,,DESP_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; desmosome organization [GO:0002934]; epidermis development [GO:0008544]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to adherens junction [GO:0071896]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060] comp138081_c0_seq3,1163,43.6801,0.4413901,0,0,,1.00E-27,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp138081_c0_seq4,1619,43.4836,0.42735975,0,0,,1.00E-21,Q96JQ2,Calmin (Calponin-like transmembrane domain protein),Calmin (Calponin-like transmembrane domain protein),GO:0005737; GO:0016021; GO:0008285; GO:0031175,cytoplasm; integral to membrane; negative regulation of cell proliferation; neuron projection development,PF00307;,1.00E-17,CHOYP_LOC100876515.1.2,,,,,,,CLMN_HUMAN,Homo sapiens (Human),negative regulation of cell proliferation [GO:0008285]; neuron projection development [GO:0031175] comp138081_c0_seq5,2685,44.4693,0.50373956,0,0,,4.00E-26,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp138081_c0_seq6,3379,44.1255,0.53974215,0,0,,0,P30427,Plectin (PCN) (PLTN) (Plectin-1),Plectin (PCN) (PLTN) (Plectin-1),GO:0016324; GO:0009925; GO:0043034; GO:0008092; GO:0005856; GO:0030855; GO:0007565; GO:0030056; GO:0031581; GO:0048471; GO:0047485; GO:0007584; GO:0042383; GO:0016528; GO:0005200,apical plasma membrane; basal plasma membrane; costamere; cytoskeletal protein binding; cytoskeleton; epithelial cell differentiation; female pregnancy; hemidesmosome; hemidesmosome assembly; perinuclear region of cytoplasm; protein N-terminus binding; response to nutrient; sarcolemma; sarcoplasm; structural constituent of cytoskeleton,PF00307;PF00681;PF03501;,9.00E-150,CHOYP_LOC100118464.1.1,,,,,,,PLEC_RAT,Rattus norvegicus (Rat),epithelial cell differentiation [GO:0030855]; female pregnancy [GO:0007565]; hemidesmosome assembly [GO:0031581]; response to nutrient [GO:0007584] comp138081_c0_seq8,1572,44.7837,0.53916046,0,0,,1.00E-58,E9Q557,Desmoplakin (DP),Desmoplakin (DP),GO:0034332; GO:0016323; GO:0086069; GO:0016337; GO:0001533; GO:0030057; GO:0002934; GO:0014704; GO:0045109; GO:0030216; GO:0005739; GO:0018149; GO:0071896; GO:0086091; GO:0086005; GO:0043588; GO:0005198; GO:0003223,adherens junction organization; basolateral plasma membrane; bundle of His cell to Purkinje myocyte communication; cell-cell adhesion; cornified envelope; desmosome; desmosome organization; intercalated disc; intermediate filament organization; keratinocyte differentiation; mitochondrion; peptide cross-linking; protein localization to adherens junction; regulation of heart rate by cardiac conduction; regulation of ventricular cardiac muscle cell action potential; skin development; structural molecule activity; ventricular compact myocardium morphogenesis,PF00681;,,,1.00E-28,ruditapes_c30249,,,,,DESP_MOUSE,Mus musculus (Mouse),adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; desmosome organization [GO:0002934]; intermediate filament cytoskeleton organization [GO:0045104]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to adherens junction [GO:0071896]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; single organismal cell-cell adhesion [GO:0016337]; skin development [GO:0043588]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060] comp138083_c0_seq1,1544,42.228,0.35321028,30,71,,4.00E-149,Q6DDU8,Fidgetin-like protein 1 (EC 3.6.4.-),Fidgetin-like protein 1 (EC 3.6.4.-),GO:0005524; GO:0046034; GO:0016787; GO:0000287; GO:0000228; GO:0017111,ATP binding; ATP metabolic process; hydrolase activity; magnesium ion binding; nuclear chromosome; nucleoside-triphosphatase activity,PF00004;PF09336;,,,,,,,,,FIGL1_XENLA,Xenopus laevis (African clawed frog),ATP metabolic process [GO:0046034] comp138083_c0_seq2,914,44.3107,0.36530636,3,0,,2.00E-86,Q5ZK92,Spastin (EC 3.6.4.3),Spastin (EC 3.6.4.3),GO:0005524; GO:0043014; GO:0007409; GO:0048487; GO:0007049; GO:0051301; GO:0005813; GO:0016021; GO:0005874; GO:0008017; GO:0001578; GO:0051013; GO:0008568; GO:0005634; GO:0048471; GO:0031117; GO:0034214; GO:0051260,ATP binding; alpha-tubulin binding; axonogenesis; beta-tubulin binding; cell cycle; cell division; centrosome; integral to membrane; microtubule; microtubule binding; microtubule bundle formation; microtubule severing; microtubule-severing ATPase activity; nucleus; perinuclear region of cytoplasm; positive regulation of microtubule depolymerization; protein hexamerization; protein homooligomerization,PF00004;PF09336;,2.00E-133,CHOYP_LOC578480.1.1,,,,,,,SPAST_CHICK,Gallus gallus (Chicken),anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; cytoplasmic microtubule organization [GO:0031122]; ER to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear envelope reassembly [GO:0031468]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260] comp138083_c0_seq3,1113,44.4744,0.41109802,0,0,,5.00E-98,Q60QD1,Fidgetin-like protein 1 (EC 3.6.4.-),Fidgetin-like protein 1 (EC 3.6.4.-),GO:0005524; GO:0046034; GO:0051301; GO:0016787; GO:0000287; GO:0007067; GO:0017111; GO:0005634,ATP binding; ATP metabolic process; cell division; hydrolase activity; magnesium ion binding; mitosis; nucleoside-triphosphatase activity; nucleus,PF00004;PF09336;,2.00E-133,CHOYP_LOC578480.1.1,,,,,,,FIGL1_CAEBR,Caenorhabditis briggsae,ATP metabolic process [GO:0046034]; cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; mitotic nuclear division [GO:0007067]; regulation of double-strand break repair via homologous recombination [GO:0010569] comp138084_c1_seq1,270,17.7778,0,0,2,,,,,,,,,,,1.00E-12,ruditapes2_c564,,,,,,, comp138087_c0_seq1,274,27.7372,0.95487383,7,55,,,,,,,,,,,5.00E-11,ruditapes_c9835,,,,,,, comp138087_c0_seq2,1214,29.5717,0.83193334,7,46,,4.00E-17,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp138087_c0_seq4,1302,29.8003,1.00926876,2,80,,3.00E-17,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp138088_c1_seq1,1410,42.6241,0.4711817,264,1700,,2.00E-139,Q4V7F3,"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.-) (O-sialoglycoprotein endopeptidase-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1) (tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1)","Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1) (tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1)",GO:0005739; GO:0008033,mitochondrion; tRNA processing,PF00814;,,,,,,,,,OSGP2_RAT,Rattus norvegicus (Rat),tRNA threonylcarbamoyladenosine modification [GO:0002949] comp138089_c4_seq1,2093,44.8161,0.9533915,11,718,,2.00E-75,O77793,Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],GO:0005509; GO:0005544; GO:0016023; GO:0004622; GO:0004623; GO:0009395,calcium ion binding; calcium-dependent phospholipid binding; cytoplasmic membrane-bounded vesicle; lysophospholipase activity; phospholipase A2 activity; phospholipid catabolic process,PF00168;PF01735;,3.00E-58,CHOYP_PA24A.2.3,3.00E-37,ruditapes_c10591,,,,,PA24A_HORSE,Equus caballus (Horse),phospholipid catabolic process [GO:0009395] comp138094_c1_seq1,255,44.3137,0.64161388,10,18,,1.00E-10,Q86YR7,Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2),Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF13716;PF00621;,,,,,,,,,MF2L2_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp138094_c1_seq3,481,44.2827,0.5979115,3,0,,7.00E-29,O60229,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0015629; GO:0097190; GO:0005829; GO:0005085; GO:0046872; GO:0007399; GO:0048011; GO:0005543; GO:0043065; GO:0004674; GO:0035023; GO:0051056; GO:0007264; GO:0016192,ATP binding; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton; apoptotic signaling pathway; cytosol; guanyl-nucleotide exchange factor activity; metal ion binding; nervous system development; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; vesicle-mediated transport,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;,,,,,,,,,KALRN_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp138094_c1_seq4,465,43.6559,0.58976129,2,9,,3.00E-26,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,,,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp138094_c1_seq5,435,44.1379,0.57393897,0,0,,5.00E-40,O60229,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0015629; GO:0097190; GO:0005829; GO:0005085; GO:0046872; GO:0007399; GO:0048011; GO:0005543; GO:0043065; GO:0004674; GO:0035023; GO:0051056; GO:0007264; GO:0016192,ATP binding; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton; apoptotic signaling pathway; cytosol; guanyl-nucleotide exchange factor activity; metal ion binding; nervous system development; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; vesicle-mediated transport,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;,,,,,,,,,KALRN_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp138094_c1_seq6,419,43.4368,0.5622522,3,5,,2.00E-36,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,1.00E-35,CHOYP_KALRN.2.2,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp138095_c0_seq1,1054,39.3738,0.5473287,64,260,,2.00E-59,Q54CS8,Peroxisomal biogenesis factor 6 (Peroxin-6),Peroxisomal biogenesis factor 6 (Peroxin-6),GO:0005524; GO:0017111; GO:0005778; GO:0005777; GO:0007031,ATP binding; nucleoside-triphosphatase activity; peroxisomal membrane; peroxisome; peroxisome organization,PF00004;,,,,,,,,,PEX6_DICDI,Dictyostelium discoideum (Slime mold),peroxisome organization [GO:0007031] comp138095_c1_seq1,878,48.4055,0.35202288,33,91,,4.00E-67,Q99LC9,Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1),Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1),GO:0005524; GO:0042623; GO:0005829; GO:0005778; GO:0016561; GO:0050821,"ATP binding; ATPase activity, coupled; cytosol; peroxisomal membrane; protein import into peroxisome matrix, translocation; protein stabilization",PF00004;,2.00E-69,CHOYP_LOC101175128.1.1,,,,,,,PEX6_MOUSE,Mus musculus (Mouse),"peroxisome organization [GO:0007031]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]" comp138097_c0_seq2,2175,45.0115,1.06541703,10,0,,1.00E-91,O16098,Maltase 1 (EC 3.2.1.20),Maltase 1 (EC 3.2.1.20),GO:0005975; GO:0043169; GO:0032450,carbohydrate metabolic process; cation binding; maltose alpha-glucosidase activity,PF00128;,1.00E-18,CHOYP_BRAFLDRAFT_265208.6.7,,,,,,,MAL1_DROVI,Drosophila virilis (Fruit fly), comp138097_c0_seq3,2188,44.7898,1.06925842,10,23,,3.00E-94,Q64319,"Neutral and basic amino acid transport protein rBAT (B(0,+)-type amino acid transport protein) (NAA-TR) (D2) (Solute carrier family 3 member 1)","Neutral and basic amino acid transport protein rBAT (D2) (Solute carrier family 3 member 1) (b(0,+)-type amino acid transport protein) (NAA-TR)",GO:0006865; GO:0005975; GO:0003824; GO:0043169; GO:0005887; GO:0046982; GO:0005774,amino acid transport; carbohydrate metabolic process; catalytic activity; cation binding; integral to plasma membrane; protein heterodimerization activity; vacuolar membrane,PF00128;,,,,,,,,,SLC31_RAT,Rattus norvegicus (Rat),amino acid transport [GO:0006865]; carbohydrate metabolic process [GO:0005975] comp138097_c0_seq4,1551,43.7137,1.13727453,0,0,,6.00E-75,O16098,Maltase 1 (EC 3.2.1.20),Maltase 1 (EC 3.2.1.20),GO:0005975; GO:0043169; GO:0032450,carbohydrate metabolic process; cation binding; maltose alpha-glucosidase activity,PF00128;,,,5.00E-26,ruditapes2_c1147,,,,,MAL1_DROVI,Drosophila virilis (Fruit fly), comp138100_c1_seq1,2824,43.1657,0.4892967,128,385,,0,Q01780,Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2),Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2),GO:0008408; GO:0071034; GO:0003723; GO:0005737; GO:0009048; GO:0004532; GO:0000178; GO:0071044; GO:0000460; GO:0000176; GO:0071035; GO:0071048; GO:0000184; GO:0005730; GO:0000166; GO:0035327,"3'-5' exonuclease activity; CUT catabolic process; RNA binding; cytoplasm; dosage compensation by inactivation of X chromosome; exoribonuclease activity; exosome (RNase complex); histone mRNA catabolic process; maturation of 5.8S rRNA; nuclear exosome (RNase complex); nuclear polyadenylation-dependent rRNA catabolic process; nuclear retention of unspliced pre-mRNA at the site of transcription; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleolus; nucleotide binding; transcriptionally active chromatin",PF01612;PF00570;PF08066;,2.00E-87,CHOYP_EXOSC10.1.1,,,,,,,EXOSX_HUMAN,Homo sapiens (Human),"CUT catabolic process [GO:0071034]; dosage compensation by inactivation of X chromosome [GO:0009048]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]" comp138101_c0_seq1,2697,35.2985,0.54813099,58,635,,5.00E-43,Q04832,DNA-binding protein HEXBP (Hexamer-binding protein),DNA-binding protein HEXBP (Hexamer-binding protein),GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,PF00098;,,,,,,,,,HEXP_LEIMA,Leishmania major, comp138101_c0_seq2,2674,35.5273,0.54585515,1719,4647,,2.00E-29,P53849,Zinc finger protein GIS2,Zinc finger protein GIS2,GO:0000932; GO:0010494; GO:0003729; GO:0042788; GO:0045727; GO:0003697; GO:0045182; GO:0008270,cytoplasmic mRNA processing body; cytoplasmic stress granule; mRNA binding; polysomal ribosome; positive regulation of translation; single-stranded DNA binding; translation regulator activity; zinc ion binding,PF00098;,,,,,,,,,GIS2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),positive regulation of translation [GO:0045727] comp138103_c0_seq1,621,44.4444,0.55535858,59,51,,9.00E-34,P31396,Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0000977; GO:0004879; GO:0007552; GO:0016319; GO:0000122; GO:0005634; GO:0045944; GO:0040034; GO:0003707; GO:0004887; GO:0008270,"RNA polymerase II regulatory region sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metamorphosis; mushroom body development; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of development, heterochronic; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,2.00E-23,CHOYP_LOC663422.1.1,,,,,,,HR3_DROME,Drosophila melanogaster (Fruit fly),"metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]" comp138104_c0_seq1,1551,41.5216,0.35349589,98,340,,8.00E-25,Q5F457,WW domain-binding protein 4 (WBP-4),WW domain-binding protein 4 (WBP-4),GO:0008380; GO:0006397; GO:0016607; GO:0003676; GO:0005681; GO:0008270,RNA splicing; mRNA processing; nuclear speck; nucleic acid binding; spliceosomal complex; zinc ion binding,PF00397;PF06220;,7.00E-46,CHOYP_LOC100373917.1.1,,,,,,,WBP4_CHICK,Gallus gallus (Chicken),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp138104_c0_seq2,558,42.8315,0.37516899,3,14,,,,,,,,,2.00E-46,CHOYP_LOC100373917.1.1,,,,,,,,, comp138108_c1_seq1,1827,40.0109,0.41084819,0,0,,3.00E-158,Q8AWD2,Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)],Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)],GO:0005524; GO:0006777; GO:0042292; GO:0005829; GO:0018192; GO:0046872; GO:0016779; GO:0034227; GO:0002098; GO:0004792,ATP binding; Mo-molybdopterin cofactor biosynthetic process; URM1 activating enzyme activity; cytosol; enzyme active site formation via L-cysteine persulfide; metal ion binding; nucleotidyltransferase activity; tRNA thio-modification; tRNA wobble uridine modification; thiosulfate sulfurtransferase activity,PF00581;PF00899;,,,,,,,,,MOCS3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),enzyme active site formation via cysteine modification to L-cysteine persulfide [GO:0018192]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098] comp138108_c1_seq2,1718,39.6391,0.43086445,15,67,,4.00E-12,P92974,Ubiquitin-activating enzyme E1 2 (AtUBA2),Ubiquitin-activating enzyme E1 2 (AtUBA2) (EC 6.2.1.45),GO:0005524; GO:0005829; GO:0005634; GO:0008641; GO:0004842,ATP binding; cytosol; nucleus; small protein activating enzyme activity; ubiquitin-protein ligase activity,PF16191;PF16190;PF09358;PF00899;PF10585;,,,,,,,,,UBE12_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ubiquitination [GO:0016567] comp138108_c1_seq3,1787,40.4589,0.3969502,0,0,,3.00E-127,Q55FS0,Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Ubiquitin-like protein activator 4 homolog) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)],Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Ubiquitin-like protein activator 4 homolog) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)],GO:0005524; GO:0006777; GO:0005829; GO:0046872; GO:0055114; GO:0016491; GO:0008033; GO:0004792,ATP binding; Mo-molybdopterin cofactor biosynthetic process; cytosol; metal ion binding; oxidation-reduction process; oxidoreductase activity; tRNA processing; thiosulfate sulfurtransferase activity,PF00581;PF00899;,2.00E-97,CHOYP_MOCS3.1.1,,,,,,,MOCS3_DICDI,Dictyostelium discoideum (Slime mold),enzyme active site formation via cysteine modification to L-cysteine persulfide [GO:0018192]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; protein urmylation [GO:0032447]; tRNA wobble position uridine thiolation [GO:0002143] comp138108_c1_seq4,1678,40.0477,0.41704309,0,0,,2.00E-08,P31252,Ubiquitin-activating enzyme E1 3,Ubiquitin-activating enzyme E1 3 (EC 6.2.1.45),GO:0005524; GO:0016874; GO:0016567; GO:0008641,ATP binding; ligase activity; protein ubiquitination; small protein activating enzyme activity,PF16191;PF16190;PF09358;PF00899;PF10585;,,,,,,,,,UBE13_WHEAT,Triticum aestivum (Wheat),protein ubiquitination [GO:0016567] comp138110_c0_seq2,2877,43.8999,0.5944694,63,21,,1.00E-115,Q99758,ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),GO:0005524; GO:0042626; GO:0097208; GO:0097233; GO:0016021; GO:0005886; GO:0042493,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; alveolar lamellar body; alveolar lamellar body membrane; integral to membrane; plasma membrane; response to drug",PF00005;,1.00E-57,CHOYP_LOC100373083.2.2,,,,,,,ABCA3_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp138110_c0_seq4,656,45.7317,0.58660851,34,10,,3.00E-61,O95477,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0044255; GO:0071222; GO:0071300; GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0042157; GO:0007040; GO:0045121; GO:0010887; GO:0010745; GO:0002790; GO:0045335; GO:0006911; GO:0005543; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular lipid metabolic process; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lipoprotein metabolic process; lysosome organization; membrane raft; negative regulation of cholesterol storage; negative regulation of macrophage derived foam cell differentiation; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid binding; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,6.00E-17,CHOYP_ABCA1.3.3,,,,,,,ABCA1_HUMAN,Homo sapiens (Human),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp138110_c0_seq5,2297,44.2316,0.59728845,0,0,,7.00E-73,Q99758,ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),GO:0005524; GO:0042626; GO:0097208; GO:0097233; GO:0016021; GO:0005886; GO:0042493,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; alveolar lamellar body; alveolar lamellar body membrane; integral to membrane; plasma membrane; response to drug",PF00005;,9.00E-47,CHOYP_LOC100373083.1.2,,,,,,,ABCA3_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp138110_c1_seq1,1152,37.2396,0.30073053,53,21,,,,,,,,,2.00E-13,CHOYP_TRIADDRAFT_53677.1.1,,,,,,,,, comp138111_c0_seq1,291,42.268,0.24000283,4,11,,3.00E-26,Q8WY64,E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),GO:0006928; GO:0042632; GO:0005737; GO:0008092; GO:0005856; GO:0019898; GO:0005622; GO:0010989; GO:0007399; GO:0005886; GO:0045732; GO:0031648; GO:0042787; GO:0032803; GO:0004842; GO:0008270,cellular component movement; cholesterol homeostasis; cytoplasm; cytoskeletal protein binding; cytoskeleton; extrinsic to membrane; intracellular; negative regulation of low-density lipoprotein particle clearance; nervous system development; plasma membrane; positive regulation of protein catabolic process; protein destabilization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of low-density lipoprotein particle receptor catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF09380;PF00373;PF09379;,,,,,,,,,MYLIP_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; movement of cell or subcellular component [GO:0006928]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803] comp138111_c1_seq1,2610,35.7471,0.37024239,12,24,,5.00E-13,Q55ED1,Probable nucleosome assembly protein,Probable nucleosome assembly protein,GO:0005737; GO:0042393; GO:0006334; GO:0005634,cytoplasm; histone binding; nucleosome assembly; nucleus,PF00956;,,,,,,,,,NAP1_DICDI,Dictyostelium discoideum (Slime mold),nucleosome assembly [GO:0006334] comp138111_c1_seq2,2551,35.9859,0.36104941,7,0,,1.00E-73,P53997,Protein SET,Protein SET,GO:0006334; GO:0005634,nucleosome assembly; nucleus,PF00956;,5.00E-63,CHOYP_ISCW_ISCW021350.1.1,,,,,,,SET_DROME,Drosophila melanogaster (Fruit fly),nucleosome assembly [GO:0006334] comp138111_c2_seq1,1361,37.252,0.67696044,30,71,,1.00E-42,Q05AK5,E3 ubiquitin-protein ligase MYLIP-B (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein B) (MIR-B),E3 ubiquitin-protein ligase MYLIP-B (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein B) (MIR-B),GO:0005737; GO:0005856; GO:0005829; GO:0007369; GO:0016874; GO:0030178; GO:0016567; GO:0008270,cytoplasm; cytoskeleton; cytosol; gastrulation; ligase activity; negative regulation of Wnt receptor signaling pathway; protein ubiquitination; zinc ion binding,PF00373;PF09379;,,,,,,,,,MYLIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567] comp138111_c2_seq2,1058,33.9319,0.63633833,6,0,,1.00E-06,O62640,Putative inhibitor of apoptosis,Putative inhibitor of apoptosis,GO:0006915; GO:0005737; GO:0070266; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0016567; GO:0042981; GO:0004842; GO:0008270,apoptotic process; cytoplasm; necroptosis; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; protein ubiquitination; regulation of apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,PIAP_PIG,Sus scrofa (Pig),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121] comp138115_c1_seq4,281,37.0107,0.20865969,0,0,,,,,,,,,,,1.00E-12,ruditapes_c15855,,,,,,, comp138118_c0_seq1,1564,41.8798,0.36911785,10,180,,1.00E-36,O94431,Uncharacterized aminotransferase C660.12c (EC 2.6.-.-),Hercynylcysteine sulfoxide lyase (EC 4.4.1.-) (Ergothioneine biosynthesis protein 2) (PLP-binding cysteine desulfurase) (PLP-dependent C-S lyase),GO:0005829; GO:0005634; GO:0030170; GO:0008483,cytosol; nucleus; pyridoxal phosphate binding; transaminase activity,PF00266;,,,,,,,,,YHKC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ergothioneine biosynthetic process [GO:0052699]; selenoneine biosynthetic process [GO:1903257] comp138119_c0_seq2,680,45.5882,0.66535125,0,11,,1.00E-17,Q6DRI7,ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51),ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF00271;,,,,,,,,,DDX51_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp138119_c0_seq4,1848,44.4805,0.47746231,110,228,,0,Q9UJV9,Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog),Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog),GO:0005524; GO:0008026; GO:0003677; GO:0003723; GO:0006915; GO:0071013; GO:0035458; GO:0005829; GO:0051607; GO:0005783; GO:0045087; GO:0000398; GO:0007275; GO:0045944; GO:0032481; GO:0008270,"ATP binding; ATP-dependent helicase activity; DNA binding; RNA binding; apoptotic process; catalytic step 2 spliceosome; cellular response to interferon-beta; cytosol; defense response to virus; endoplasmic reticulum; innate immune response; mRNA splicing, via spliceosome; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type I interferon production; zinc ion binding",PF00270;PF00271;,0,CHOYP_DDX41.1.1,,,,,,,DDX41_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to interferon-beta [GO:0035458]; defense response to virus [GO:0051607]; mRNA splicing, via spliceosome [GO:0000398]; multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of type I interferon production [GO:0032479]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]" comp138121_c1_seq2,865,40.4624,0.80448666,229,669,,2.00E-46,Q7T0P7,Mitochondrial inner membrane protease ATP23 homolog (EC 3.4.24.-),Mitochondrial inner membrane protease ATP23 homolog (EC 3.4.24.-),GO:0046872; GO:0004222; GO:0006508,metal ion binding; metalloendopeptidase activity; proteolysis,PF09768;,,,1.00E-17,ruditapes_c25516,,,,,ATP23_XENLA,Xenopus laevis (African clawed frog), comp138125_c0_seq1,1424,36.6573,0.2155956,5,9,,1.00E-81,Q6DIZ0,"3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD)","3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD)",GO:0000334; GO:0009435; GO:0005737; GO:0005506,"3-hydroxyanthranilate 3,4-dioxygenase activity; NAD biosynthetic process; cytoplasm; iron ion binding",PF06052;,1.00E-74,CHOYP_LOC582154.1.1,,,,,,,3HAO_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569] comp138127_c0_seq1,1080,37.5926,0.57761204,0,123,,2.00E-13,A8GHY0,Co-chaperone protein HscB (Hsc20),Co-chaperone protein HscB (Hsc20),GO:0006457; GO:0051259,protein folding; protein oligomerization,PF00226;PF07743;,,,,,,,,,HSCB_SERP5,Serratia proteamaculans (strain 568),protein folding [GO:0006457]; protein oligomerization [GO:0051259] comp138127_c0_seq3,1065,37.4648,0.56348217,19,129,,2.00E-26,Q8K3A0,"Iron-sulfur cluster co-chaperone protein HscB, mitochondrial (Hsc20)","Iron-sulfur cluster co-chaperone protein HscB, mitochondrial (Hsc20)",GO:0016226; GO:0046872; GO:0005739; GO:0006457; GO:0051259,iron-sulfur cluster assembly; metal ion binding; mitochondrion; protein folding; protein oligomerization,PF07743;,,,,,,,,,HSC20_MOUSE,Mus musculus (Mouse),iron-sulfur cluster assembly [GO:0016226]; protein folding [GO:0006457]; protein oligomerization [GO:0051259] comp138128_c0_seq10,2181,44.2458,0.53425269,0,0,,5.00E-09,Q63638,Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),GO:0005524; GO:0042692; GO:0005634; GO:0004674,ATP binding; muscle cell differentiation; nucleus; protein serine/threonine kinase activity,PF07679;PF00069;,,,,,,,,,SPEG_RAT,Rattus norvegicus (Rat),muscle cell differentiation [GO:0042692] comp138128_c0_seq11,746,42.7614,0.3239126,0,0,,1.00E-15,P56276,Telokin,Telokin,,,PF07679;,6.00E-18,CHOYP_TITIN.18.19,,,,,,,MYLK_MELGA,Meleagris gallopavo (Common turkey), comp138128_c0_seq14,1411,44.224,0.43517589,0,0,,4.00E-12,Q5DTJ9,Myopalladin,Myopalladin,GO:0031674; GO:0030018; GO:0015630; GO:0005634; GO:0045214,I band; Z disc; microtubule cytoskeleton; nucleus; sarcomere organization,PF07679;,,,,,,,,,MYPN_MOUSE,Mus musculus (Mouse),sarcomere organization [GO:0045214] comp138128_c0_seq15,424,47.8774,0.16549936,23,7,,6.00E-11,Q0ZGT2,Nexilin (F-actin-binding protein) (Nelin),Nexilin (F-actin-binding protein) (Nelin),GO:0030018; GO:0051015; GO:0005924; GO:0005856; GO:0030334; GO:0051493; GO:0008307,Z disc; actin filament binding; cell-substrate adherens junction; cytoskeleton; regulation of cell migration; regulation of cytoskeleton organization; structural constituent of muscle,PF07679;,,,2.00E-11,ruditapes_c15534,,,,,NEXN_HUMAN,Homo sapiens (Human),cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] comp138128_c0_seq17,1042,41.9386,0.65581046,0,0,,6.00E-09,Q8NFZ8,Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2),Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2),GO:0007155; GO:0016021,cell adhesion; integral to membrane,PF08205;PF07686;,,,,,,,,,CADM4_HUMAN,Homo sapiens (Human),cell recognition [GO:0008037]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp138128_c0_seq18,2035,44.6683,0.55198069,0,0,,1.00E-15,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp138128_c0_seq19,2550,44.2353,0.52143746,0,0,,1.00E-10,A2AAJ9,Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),GO:0005524; GO:0031430; GO:0005089; GO:0030154; GO:0007275; GO:0018108; GO:0005543; GO:0004674; GO:0004713; GO:0035023,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; cell differentiation; multicellular organismal development; peptidyl-tyrosine phosphorylation; phospholipid binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of Rho protein signal transduction,PF00041;PF07679;PF00612;PF00069;PF00621;,2.00E-17,CHOYP_TITIN.19.19,,,,,,,OBSCN_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023] comp138128_c0_seq20,747,45.3815,0.59923479,0,0,,2.00E-15,P56276,Telokin,Telokin,,,PF07679;,6.00E-18,CHOYP_TITIN.18.19,,,,,,,MYLK_MELGA,Meleagris gallopavo (Common turkey), comp138128_c0_seq21,2579,42.4583,0.49066784,0,0,,1.00E-19,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp138128_c0_seq22,2433,42.7045,0.505159,0,0,,3.00E-08,Q9Z2J4,Nexilin,Nexilin,GO:0030018; GO:0051015; GO:0005924; GO:0005856; GO:0030334; GO:0051493; GO:0008307,Z disc; actin filament binding; cell-substrate adherens junction; cytoskeleton; regulation of cell migration; regulation of cytoskeleton organization; structural constituent of muscle,PF07679;,,,,,,,,,NEXN_RAT,Rattus norvegicus (Rat),cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] comp138128_c0_seq23,812,42.734,0.35293582,0,0,,1.00E-15,P56276,Telokin,Telokin,,,PF07679;,,,,,,,,,MYLK_MELGA,Meleagris gallopavo (Common turkey), comp138128_c0_seq25,1382,47.5398,0.48714362,0,0,,6.00E-13,O02827,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] (Fragment)","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] (Fragment)",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity,PF07679;PF00069;,1.00E-17,CHOYP_TITIN.19.19,,,,,,,MYLK_SHEEP,Ovis aries (Sheep), comp138128_c0_seq26,2457,42.5722,0.50337915,0,0,,1.00E-19,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp138128_c0_seq28,1440,39.375,0.53847713,0,0,,4.00E-11,Q15772,Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),GO:0005524; GO:0055013; GO:0001701; GO:0007517; GO:0008285; GO:0005634; GO:0004674; GO:0060541,ATP binding; cardiac muscle cell development; in utero embryonic development; muscle organ development; negative regulation of cell proliferation; nucleus; protein serine/threonine kinase activity; respiratory system development,PF07679;PF00069;,,,,,,,,,SPEG_HUMAN,Homo sapiens (Human),muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; negative regulation of cell proliferation [GO:0008285] comp138128_c0_seq3,1448,47.3066,0.49447198,0,0,,2.00E-14,P56276,Telokin,Telokin,,,PF07679;,,,,,,,,,MYLK_MELGA,Meleagris gallopavo (Common turkey), comp138128_c0_seq30,813,45.1415,0.60565568,0,0,,,,,,,,,6.00E-18,CHOYP_TITIN.19.19,,,,,,,,, comp138128_c0_seq31,1265,44.9012,0.4552435,0,0,,1.00E-11,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp138128_c0_seq32,1289,44.6082,0.45270854,0,0,,2.00E-11,Q86TC9,Myopalladin (145 kDa sarcomeric protein),Myopalladin (145 kDa sarcomeric protein),GO:0031674; GO:0030018; GO:0015630; GO:0005634; GO:0045214,I band; Z disc; microtubule cytoskeleton; nucleus; sarcomere organization,PF07679;,,,,,,,,,MYPN_HUMAN,Homo sapiens (Human),sarcomere organization [GO:0045214] comp138128_c0_seq33,2059,44.4876,0.55001706,0,0,,1.00E-15,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp138128_c0_seq34,2617,44.2109,0.52441409,0,0,,1.00E-19,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp138128_c0_seq35,808,43.6881,0.41963366,0,5,,3.00E-07,Q9UBF9,Myotilin (57 kDa cytoskeletal protein) (Myofibrillar titin-like Ig domains protein) (Titin immunoglobulin domain protein),Myotilin (57 kDa cytoskeletal protein) (Myofibrillar titin-like Ig domains protein) (Titin immunoglobulin domain protein),GO:0030018; GO:0015629; GO:0006936; GO:0042383; GO:0008307,Z disc; actin cytoskeleton; muscle contraction; sarcolemma; structural constituent of muscle,PF07679;,,,,,,,,,MYOTI_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936] comp138128_c0_seq5,659,47.7997,0.29290796,1,0,,2.00E-10,A1KZ92,Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1),Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1),GO:0005737; GO:0004519; GO:0005615; GO:0020037; GO:0042744; GO:0046872; GO:0090305; GO:0004601,cytoplasm; endonuclease activity; extracellular space; heme binding; hydrogen peroxide catabolic process; metal ion binding; nucleic acid phosphodiester bond hydrolysis; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDNL_HUMAN,Homo sapiens (Human),hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979] comp138128_c0_seq7,2218,46.2579,0.56514842,0,0,,5.00E-16,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp138128_c0_seq8,2152,46.3755,0.56210724,0,0,,5.00E-16,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,2.00E-17,CHOYP_TITIN.19.19,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp138128_c0_seq9,345,46.3768,0.27048382,0,0,,9.00E-08,O15394,Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2),Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2),GO:0030424; GO:0016021; GO:0007158; GO:0005886,axon; integral to membrane; neuron cell-cell adhesion; plasma membrane,PF00041;PF07679;,,,,,,,,,NCAM2_HUMAN,Homo sapiens (Human),neuron cell-cell adhesion [GO:0007158] comp138132_c2_seq2,1734,34.3137,0.55019498,2,0,,,,,,,,,4.00E-18,CHOYP_GPBP1.1.1,,,,,,,,, comp138138_c0_seq1,2168,39.9908,0.64935967,4,260,,0,O62698,Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2),Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2),GO:0019371; GO:0051213; GO:0005789; GO:0020037; GO:0046872; GO:0004601; GO:0004666; GO:0006979,cyclooxygenase pathway; dioxygenase activity; endoplasmic reticulum membrane; heme binding; metal ion binding; peroxidase activity; prostaglandin-endoperoxide synthase activity; response to oxidative stress,PF03098;PF00008;,8.00E-60,CHOYP_PGH2.2.2,,,,,,,PGH2_BOVIN,Bos taurus (Bovine),cellular response to interleukin-1 [GO:0071347]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; meiotic spindle organization [GO:0000212]; ovarian cumulus expansion [GO:0001550]; positive regulation of embryonic development [GO:0040019]; positive regulation of meiotic cell cycle process involved in oocyte maturation [GO:1904146]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of protein phosphorylation [GO:0001934]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979] comp138141_c1_seq1,1577,41.6614,0.45460309,2,6,,4.00E-17,Q9SAJ3,"ATP-dependent zinc metalloprotease FTSH 12, chloroplastic (AtFTSH12) (EC 3.4.24.-)","ATP-dependent zinc metalloprotease FTSH 12, chloroplastic (AtFTSH12) (EC 3.4.24.-)",GO:0005524; GO:0004176; GO:0009941; GO:0009535; GO:0016021; GO:0046872; GO:0004222; GO:0005739; GO:0006508,ATP binding; ATP-dependent peptidase activity; chloroplast envelope; chloroplast thylakoid membrane; integral to membrane; metal ion binding; metalloendopeptidase activity; mitochondrion; proteolysis,PF00004;PF01434;,3.00E-89,CHOYP_LOC100368955.1.1,,,,,,,FTSHC_ARATH,Arabidopsis thaliana (Mouse-ear cress),proteolysis [GO:0006508] comp138141_c1_seq2,1815,42.1488,0.42271315,2,10,,1.00E-69,Q09803,Suppressor protein of bem1/bed5 double mutants (EC 3.6.4.6),Suppressor protein of bem1/bed5 double mutants (EC 3.6.4.6),GO:0005524; GO:0016887; GO:0005829; GO:0010008; GO:0005634; GO:0045053; GO:0043328,ATP binding; ATPase activity; cytosol; endosome membrane; nucleus; protein retention in Golgi apparatus; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF00004;PF04212;PF09336;,,,,,,,,,VPS4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),late endosome to vacuole transport [GO:0045324]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; vacuole organization [GO:0007033] comp138141_c1_seq4,1828,42.1225,0.43262453,12,6,,4.00E-84,P52917,Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10),Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10),GO:0005524; GO:0016887; GO:0005768; GO:0010008; GO:0070676; GO:0032511; GO:0016020; GO:0042803; GO:0051260; GO:0045053; GO:0015031; GO:0016125,ATP binding; ATPase activity; endosome; endosome membrane; intralumenal vesicle formation; late endosome to vacuole transport via multivesicular body sorting pathway; membrane; protein homodimerization activity; protein homooligomerization; protein retention in Golgi apparatus; protein transport; sterol metabolic process,PF00004;PF04212;PF09336;,5.00E-99,CHOYP_LOC100368955.1.1,,,,,,,VPS4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; protein homooligomerization [GO:0051260]; protein retention in Golgi apparatus [GO:0045053]; protein transport [GO:0015031]; sterol metabolic process [GO:0016125]; vacuole organization [GO:0007033] comp138143_c1_seq1,777,40.4118,0.55983162,61,626,,2.00E-61,Q5ZI03,Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor),Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor),GO:0008380; GO:0000118; GO:0006397; GO:0045892; GO:0016607; GO:0006351,"RNA splicing; histone deacetylase complex; mRNA processing; negative regulation of transcription, DNA-dependent; nuclear speck; transcription, DNA-dependent",PF10197;,1.00E-134,CHOYP_CIR1.1.2,,,,,,,CIR1_CHICK,Gallus gallus (Chicken),"mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp138145_c0_seq1,1502,39.1478,0.19418613,109,149,,4.00E-06,Q86YC2,Partner and localizer of BRCA2,Partner and localizer of BRCA2,GO:0003677; GO:0000724; GO:0001833; GO:0007498; GO:0043066; GO:0005654; GO:0009887; GO:0036342; GO:0001756,DNA binding; double-strand break repair via homologous recombination; inner cell mass cell proliferation; mesoderm development; negative regulation of apoptotic process; nucleoplasm; organ morphogenesis; post-anal tail morphogenesis; somitogenesis,PF16756;,,,,,,,,,PALB2_HUMAN,Homo sapiens (Human),chromosome breakage [GO:0031052]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; inner cell mass cell proliferation [GO:0001833]; mesoderm development [GO:0007498]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; organ morphogenesis [GO:0009887]; post-anal tail morphogenesis [GO:0036342]; somitogenesis [GO:0001756]; strand displacement [GO:0000732] comp138148_c0_seq1,983,38.5554,0.5844228,233,1328,,1.00E-87,A7RWC9,Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.19) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase),Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.19) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase),GO:0005737; GO:0009204; GO:0046872; GO:0047429; GO:0000166; GO:0009117,cytoplasm; deoxyribonucleoside triphosphate catabolic process; metal ion binding; nucleoside-triphosphate diphosphatase activity; nucleotide binding; nucleotide metabolic process,PF01725;,3.00E-48,CHOYP_ITPA.1.1,,,,,,,ITPA_NEMVE,Nematostella vectensis (Starlet sea anemone),deoxyribonucleoside triphosphate catabolic process [GO:0009204]; nucleotide metabolic process [GO:0009117] comp138150_c0_seq1,2560,40.9375,0.57133092,38,82,,6.00E-74,A0JNI5,"CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16)","CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16)",GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF09750;,2.00E-106,CHOYP_CLASR.1.2,,,,,,,CLASR_BOVIN,Bos taurus (Bovine),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp138150_c0_seq3,1306,41.4242,0.41978799,6,9,,,,,,,,,9.00E-107,CHOYP_CLASR.1.2,,,,,,,,, comp138152_c0_seq1,3008,38.2314,0.78576144,67,954,,4.00E-44,Q13351,Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF),Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF),GO:0006338; GO:0000987; GO:0035162; GO:0030218; GO:0043249; GO:0001701; GO:0001889; GO:0046872; GO:0000790; GO:0045893; GO:0003700; GO:0006351,"chromatin remodeling; core promoter proximal region sequence-specific DNA binding; embryonic hemopoiesis; erythrocyte differentiation; erythrocyte maturation; in utero embryonic development; liver development; metal ion binding; nuclear chromatin; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF16832;PF16833;PF00096;,2.00E-63,CHOYP_LOC100313642.1.1,,,,,,,KLF1_HUMAN,Homo sapiens (Human),"cellular response to peptide [GO:1901653]; erythrocyte differentiation [GO:0030218]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138153_c1_seq1,2429,35.8584,0.40259747,8,56,,,,,,,,,4.00E-89,CHOYP_UBCD2.1.1,,,,,,,,, comp138153_c1_seq2,2443,35.8166,0.40096114,9,71,,5.00E-92,P52485,Ubiquitin-conjugating enzyme E2-24 kDa (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Ubiquitin-conjugating enzyme E2-24 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0019915; GO:0004842,ATP binding; lipid storage; ubiquitin-protein ligase activity,PF00179;,4.00E-89,CHOYP_UBCD2.1.1,7.00E-21,ruditapes2_c904,,,,,UBCD2_DROME,Drosophila melanogaster (Fruit fly),lipid storage [GO:0019915]; protein polyubiquitination [GO:0000209] comp138154_c0_seq1,1648,40.7767,0.37106572,320,2042,,,,,,,,,3.00E-13,CHOYP_CAAP1.1.1,,,,,,,,, comp138155_c0_seq1,999,35.9359,0.5900627,665,2107,,2.00E-20,Q9VYI3,"Probable 39S ribosomal protein L49, mitochondrial (L49mt) (MRP-L49)","Probable 39S ribosomal protein L49, mitochondrial (L49mt) (MRP-L49)",GO:0005762; GO:0003735; GO:0003743,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation initiation factor activity,PF05046;,,,,,,,,,RM49_DROME,Drosophila melanogaster (Fruit fly),mitochondrial translation [GO:0032543] comp138156_c0_seq1,837,43.7276,0.7772038,0,10,,1.00E-43,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp138156_c0_seq2,1038,43.1599,0.76740265,3,9,,7.00E-45,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp138156_c0_seq3,485,38.9691,0.54606974,0,0,,2.00E-09,Q8WZ73,E3 ubiquitin-protein ligase rififylin (EC 6.3.2.-) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like),E3 ubiquitin-protein ligase rififylin (EC 6.3.2.-) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like),GO:0006915; GO:0016023; GO:0006886; GO:0016020; GO:0043161; GO:0070936; GO:0032006; GO:0010762; GO:0004842; GO:0008270,apoptotic process; cytoplasmic membrane-bounded vesicle; intracellular protein transport; membrane; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; regulation of TOR signaling cascade; regulation of fibroblast migration; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RFFL_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of fibroblast migration [GO:0010762]; regulation of TOR signaling [GO:0032006]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138156_c0_seq4,686,39.9417,0.62387953,0,21,,1.00E-08,Q557E7,E3 ubiquitin-protein ligase cblA (EC 6.3.2.-) (Cbl-like protein A) (RING finger protein cblA),E3 ubiquitin-protein ligase cblA (EC 6.3.2.-) (Cbl-like protein A) (RING finger protein cblA),GO:0005509; GO:0005829; GO:0007243; GO:0016874; GO:0005634; GO:0016567; GO:0030587; GO:0008270,calcium ion binding; cytosol; intracellular protein kinase cascade; ligase activity; nucleus; protein ubiquitination; sorocarp development; zinc ion binding,PF02761;PF00017;,,,,,,,,,CBLA_DICDI,Dictyostelium discoideum (Slime mold),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]; sorocarp development [GO:0030587] comp138156_c0_seq5,338,47.3373,0.90273347,0,0,,2.00E-20,P41436,Apoptosis inhibitor IAP,Apoptosis inhibitor IAP,GO:0006915; GO:0008270,apoptotic process; zinc ion binding,PF00653;,,,,,,,,,IAP_GVCPM,Cydia pomonella granulosis virus (isolate Mexico/1963) (CpGV) (Cydia pomonella granulovirus), comp138157_c0_seq2,1142,44.2207,0.93233013,64,5,,4.00E-13,Q90WI6,C-type lectin BML-1 (CTL),C-type lectin BML-1 (CTL),GO:0030246; GO:0005576; GO:0046872,carbohydrate binding; extracellular region; metal ion binding,PF00059;,,,,,,,,,CLEC1_BUNMU,Bungarus multicinctus (Many-banded krait), comp138158_c3_seq1,1530,45.9477,0.54523698,0,0,,1.00E-13,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp138158_c3_seq2,1697,44.5492,0.53550422,2,0,,6.00E-19,Q92766,Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1),Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1),GO:0003677; GO:0007265; GO:0005737; GO:0046872; GO:0007275; GO:0045892; GO:0016604; GO:0016607; GO:0045893; GO:0003700; GO:0006366,"DNA binding; Ras protein signal transduction; cytoplasm; metal ion binding; multicellular organismal development; negative regulation of transcription, DNA-dependent; nuclear body; nuclear speck; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter",PF13912;,,,,,,,,,RREB1_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; Ras protein signal transduction [GO:0007265]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp138158_c3_seq3,802,44.7631,0.66724297,26,45,,2.00E-09,Q96N77,Zinc finger protein 641,Zinc finger protein 641,GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0000981,DNA binding; cytoplasm; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF01352;,,,,,,,,,ZN641_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp138158_c3_seq4,1807,43.2208,0.52285948,7,38,,4.00E-18,Q3UH06,Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),GO:0003677; GO:0046872; GO:0045892; GO:0016607; GO:0003700; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nuclear speck; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13912;,9.00E-90,CHOYP_RREB1.1.1,,,,,,,RREB1_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp138159_c0_seq1,1030,36.8932,0.45695334,0,0,,3.00E-13,P39862,Capsular polysaccharide biosynthesis glycosyltransferase CapM (EC 2.4.-.-),Capsular polysaccharide biosynthesis glycosyltransferase CapM (EC 2.4.-.-),GO:0045227; GO:0016757,"capsule polysaccharide biosynthetic process; transferase activity, transferring glycosyl groups",PF13477;PF00534;,6.00E-19,CHOYP_BRAFLDRAFT_70178.1.1,,,,,,,CAPM_STAAU,Staphylococcus aureus,capsule polysaccharide biosynthetic process [GO:0045227] comp138159_c0_seq4,1510,38.1457,0.58329237,0,10,,3.00E-163,Q9H553,"Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)","Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)",GO:0004378; GO:0000033; GO:0048306; GO:0006488; GO:0005789; GO:0033164; GO:0016021; GO:0005634; GO:0048471; GO:0043687; GO:0018279; GO:0043495; GO:0033577; GO:0051592,"GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity; alpha-1,3-mannosyltransferase activity; calcium-dependent protein binding; dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum membrane; glycolipid 6-alpha-mannosyltransferase activity; integral to membrane; nucleus; perinuclear region of cytoplasm; post-translational protein modification; protein N-linked glycosylation via asparagine; protein anchor; protein glycosylation in endoplasmic reticulum; response to calcium ion",PF13439;PF00534;,6.00E-72,CHOYP_BRAFLDRAFT_70178.1.1,,,,,,,ALG2_HUMAN,Homo sapiens (Human),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation in endoplasmic reticulum [GO:0033577]; response to calcium ion [GO:0051592] comp138162_c1_seq1,1787,39.3956,0.29319175,122,421,,1.00E-164,Q6GP52,Beclin-1,Beclin-1,GO:0000139; GO:0006914; GO:0000910; GO:0051607,Golgi membrane; autophagy; cytokinesis; defense response to virus,PF04111;PF15285;,0,CHOYP_BECN1.1.1,,,,,,,BECN1_XENLA,Xenopus laevis (African clawed frog),autophagy [GO:0006914]; cytokinesis [GO:0000910]; defense response to virus [GO:0051607]; endocytosis [GO:0006897]; positive regulation of autophagy [GO:0010508]; regulation of cytokinesis [GO:0032465] comp138163_c1_seq1,1699,36.0212,0.50854718,74,416,,7.00E-65,P48506,Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase),Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase),GO:0043531; GO:0005524; GO:0019852; GO:0045454; GO:0050662; GO:0006534; GO:0005829; GO:0016595; GO:0006536; GO:0004357; GO:0017109; GO:0006750; GO:1901687; GO:0000287; GO:0043066; GO:0043524; GO:0031397; GO:0045892; GO:0032436; GO:0050880; GO:0051900; GO:0046685; GO:0009408; GO:0009725; GO:0051409; GO:0006979; GO:0006805,"ADP binding; ATP binding; L-ascorbic acid metabolic process; cell redox homeostasis; coenzyme binding; cysteine metabolic process; cytosol; glutamate binding; glutamate metabolic process; glutamate-cysteine ligase activity; glutamate-cysteine ligase complex; glutathione biosynthetic process; glutathione derivative biosynthetic process; magnesium ion binding; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; negative regulation of protein ubiquitination; negative regulation of transcription, DNA-dependent; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of blood vessel size; regulation of mitochondrial depolarization; response to arsenic-containing substance; response to heat; response to hormone stimulus; response to nitrosative stress; response to oxidative stress; xenobiotic metabolic process",PF03074;,7.00E-15,CHOYP_GSH1.1.1,,,,,,,GSH1_HUMAN,Homo sapiens (Human),"apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to arsenic-containing substance [GO:0046685]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; sulfur amino acid metabolic process [GO:0000096]" comp138171_c1_seq5,422,35.782,0.22889739,1,0,,,,,,,,,,,1.00E-14,ruditapes_c1304,,,,,,, comp138185_c0_seq1,2141,28.7249,0.36362873,259,856,,2.00E-17,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp138187_c0_seq1,812,46.4286,0.56020757,0,0,,4.00E-93,Q80SY5,Pre-mRNA-splicing factor 38B,Pre-mRNA-splicing factor 38B,GO:0008380; GO:0006397; GO:0005681,RNA splicing; mRNA processing; spliceosomal complex,PF03371;,1.00E-95,CHOYP_LOC100875404.1.1,,,,,,,PR38B_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp138187_c0_seq10,618,50.8091,0.59947944,0,0,,3.00E-27,Q6AXY7,Pre-mRNA-splicing factor 38B,Pre-mRNA-splicing factor 38B,GO:0008380; GO:0006397; GO:0005681,RNA splicing; mRNA processing; spliceosomal complex,PF03371;,,,,,,,,,PR38B_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp138187_c0_seq4,939,35.8892,0.43058541,607,1733,,3.00E-23,Q6TLE4,Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32),Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32),GO:0072546; GO:0005794; GO:0000139; GO:0005769; GO:0031901; GO:0015095,ER membrane protein complex; Golgi apparatus; Golgi membrane; early endosome; early endosome membrane; magnesium ion transmembrane transporter activity,PF10270;,1.00E-28,CHOYP_LOC100891486.1.2,2.00E-23,ruditapes_c29325,,,,,MMGT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),magnesium ion transport [GO:0015693] comp138187_c0_seq6,885,47.1186,0.58076673,0,0,,,,,,,,,1.00E-78,CHOYP_LOC100745256.1.1,,,,,,,,, comp138190_c0_seq1,1489,44.728,0.36596698,7,83,,0,C3YWU0,Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),GO:0004560; GO:0005576; GO:0006004,alpha-L-fucosidase activity; extracellular region; fucose metabolic process,PF01120;PF16757;,9.00E-146,CHOYP_LOC100367436.1.1,,,,,,,FUCO_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),fucose metabolic process [GO:0006004] comp138190_c0_seq3,745,45.2349,0.40411774,10,19,,,,,,,,,4.00E-51,CHOYP_LOC592142.9.9,,,,,,,,, comp138191_c0_seq2,2178,43.067,0.28726135,76,121,,8.00E-39,Q9HAW4,Claspin (hClaspin),Claspin (hClaspin),GO:0003677; GO:0006281; GO:0006260; GO:0031572; GO:0032147; GO:0006921; GO:0033314; GO:0005654; GO:0018105,DNA binding; DNA repair; DNA replication; G2 DNA damage checkpoint; activation of protein kinase activity; cellular component disassembly involved in execution phase of apoptosis; mitotic DNA replication checkpoint; nucleoplasm; peptidyl-serine phosphorylation,,2.00E-54,CHOYP_CLSPN.1.1,,,,,,,CLSPN_HUMAN,Homo sapiens (Human),activation of protein kinase activity [GO:0032147]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G2 DNA damage checkpoint [GO:0031572]; mitotic DNA replication checkpoint [GO:0033314]; peptidyl-serine phosphorylation [GO:0018105] comp138191_c0_seq3,1170,41.453,0.30561668,2,8,,5.00E-37,Q9DF50,Claspin (xClaspin),Claspin (xClaspin),GO:0003677; GO:0006281; GO:0031572; GO:0005634,DNA binding; DNA repair; G2 DNA damage checkpoint; nucleus,,,,,,,,,,CLSPN_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; G2 DNA damage checkpoint [GO:0031572] comp138193_c0_seq1,1433,39.8465,0.52735322,529,2159,,1.00E-178,Q5I0A0,Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1),Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1),GO:0004177; GO:0009987; GO:0005737; GO:0046872; GO:0008235; GO:0006508,aminopeptidase activity; cellular process; cytoplasm; metal ion binding; metalloexopeptidase activity; proteolysis,PF00557;PF15801;,2.00E-153,CHOYP_BRAFLDRAFT_59647.1.1,,,,,,,AMPM1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein initiator methionine removal [GO:0070084] comp138194_c0_seq1,2013,39.8907,1.19980668,2185,15,male>female,3.00E-73,P17972,Potassium voltage-gated channel protein Shaw (Shaw2),Potassium voltage-gated channel protein Shaw (Shaw2),GO:0005251; GO:0051260; GO:0030431; GO:0008076,delayed rectifier potassium channel activity; protein homooligomerization; sleep; voltage-gated potassium channel complex,PF02214;PF00520;,,,,,,,,,KCNAW_DROME,Drosophila melanogaster (Fruit fly),potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; sleep [GO:0030431] comp138195_c0_seq1,2250,35.9111,0.72462329,2801,984,,1.00E-09,Q01804,OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1),OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1),GO:0071108; GO:0006508; GO:0004843,protein K48-linked deubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,OTUD4_HUMAN,Homo sapiens (Human),protein K48-linked deubiquitination [GO:0071108] comp138196_c0_seq1,1131,37.0469,0.90332948,1856,17367,,2.00E-59,Q5R8R5,Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi),Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi),GO:0035730; GO:0097057; GO:0035731; GO:0006749; GO:0004364; GO:0005739; GO:0070373; GO:0043508; GO:2001237; GO:0032691; GO:0071638; GO:0051771; GO:0032720; GO:0005634; GO:0006805,S-nitrosoglutathione binding; TRAF2-GSTP1 complex; dinitrosyl-iron complex binding; glutathione metabolic process; glutathione transferase activity; mitochondrion; negative regulation of ERK1 and ERK2 cascade; negative regulation of JUN kinase activity; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of interleukin-1 beta production; negative regulation of monocyte chemotactic protein-1 production; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of tumor necrosis factor production; nucleus; xenobiotic metabolic process,PF14497;PF02798;,,,3.00E-22,ruditapes2_c334,,,,,GSTP1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),metabolic process [GO:0008152] comp138198_c0_seq1,3087,43.5374,0.44007807,96,97,,0,A6QLA0,"Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding protein 1)","Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding protein 1)",GO:0003677; GO:0016874; GO:0045347; GO:0000122; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; ligase activity; negative regulation of MHC class II biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01424;PF01422;,3.00E-47,CHOYP_NFX1.1.2,,,,,,,NFX1_BOVIN,Bos taurus (Bovine),negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription from RNA polymerase II promoter [GO:0006366] comp138198_c0_seq2,1849,41.4278,0.45741772,3,0,,,,,,,,,4.00E-31,CHOYP_NFX1.1.2,,,,,,,,, comp138201_c0_seq1,2924,39.7401,0.69449399,14,0,,5.00E-108,P35822,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0030424; GO:0030425; GO:0016021; GO:0043025; GO:0001750; GO:0004725,axon; dendrite; integral to membrane; neuronal cell body; photoreceptor outer segment; protein tyrosine phosphatase activity,PF00041;PF07679;PF00629;PF00102;,6.00E-75,CHOYP_PTPRK.8.20,,,,,,,PTPRK_MOUSE,Mus musculus (Mouse),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp138201_c0_seq2,2912,39.6978,0.69022647,2,0,,9.00E-112,O14522,Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho),Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho),GO:0045294; GO:0009986; GO:0045295; GO:0007156; GO:0016021; GO:0005886; GO:0004725; GO:0016790; GO:0007169,alpha-catenin binding; cell surface; gamma-catenin binding; homophilic cell adhesion; integral to membrane; plasma membrane; protein tyrosine phosphatase activity; thiolester hydrolase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF00629;PF00102;,6.00E-75,CHOYP_PTPRK.8.20,,,,,,,PTPRT_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp138201_c1_seq1,872,40.8257,0.7718843,4,0,,3.00E-06,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp138201_c1_seq2,2524,44.2948,0.69500243,0,0,,2.00E-07,Q9P232,Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein),Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein),GO:0031225; GO:0007155; GO:0007399; GO:0005886,anchored to membrane; cell adhesion; nervous system development; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN3_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; nervous system development [GO:0007399] comp138201_c1_seq3,2503,44.0671,0.71631791,0,0,,1.00E-12,Q9UMZ3,Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48),Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48),GO:0042472; GO:0016021; GO:0035335; GO:0004725; GO:0045598,inner ear morphogenesis; integral to membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; regulation of fat cell differentiation,PF00041;PF00102;,,,,,,,,,PTPRQ_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of fat cell differentiation [GO:0045598] comp138201_c1_seq4,2958,43.3063,0.70075693,0,0,,2.00E-06,Q80V70,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF12662;PF07974;PF07645;PF00053;,,,,,,,,,MEGF6_MOUSE,Mus musculus (Mouse), comp138201_c1_seq5,1341,42.431,0.59419626,0,0,,5.00E-08,Q2KIT5,Cysteine-rich with EGF-like domain protein 2,Cysteine-rich with EGF-like domain protein 2,GO:0005794; GO:0005509; GO:0005783; GO:0005615,Golgi apparatus; calcium ion binding; endoplasmic reticulum; extracellular space,PF07645;,,,,,,,,,CREL2_BOVIN,Bos taurus (Bovine), comp138201_c1_seq6,953,44.1763,0.59140443,0,0,,5.00E-07,Q80V70,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF12662;PF07974;PF07645;PF00053;,,,,,,,,,MEGF6_MOUSE,Mus musculus (Mouse), comp138201_c1_seq9,2570,44.0856,0.71320515,0,0,,1.00E-12,Q9UMZ3,Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48),Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48),GO:0042472; GO:0016021; GO:0035335; GO:0004725; GO:0045598,inner ear morphogenesis; integral to membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; regulation of fat cell differentiation,PF00041;PF00102;,,,,,,,,,PTPRQ_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of fat cell differentiation [GO:0045598] comp138203_c1_seq4,2559,39.195,0.34053536,264,1209,,9.00E-85,A5PKL6,Glutathione S-transferase C-terminal domain-containing protein,Glutathione S-transferase C-terminal domain-containing protein,,,PF13847;,,,,,,,,,GSTCD_BOVIN,Bos taurus (Bovine), comp138204_c1_seq1,1722,38.2695,1.04892392,93,364,,5.00E-23,Q03412,Innexin unc-7 (Uncoordinated protein 7),Innexin unc-7 (Uncoordinated protein 7),GO:0005921; GO:0016264; GO:0055077; GO:0016021; GO:0034220; GO:0040011; GO:0032589; GO:0018991; GO:0043051; GO:0042221,gap junction; gap junction assembly; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; locomotion; neuron projection membrane; oviposition; regulation of pharyngeal pumping; response to chemical stimulus,PF00876;,,,,,,,,,UNC7_CAEEL,Caenorhabditis elegans,gap junction assembly [GO:0016264]; ion transmembrane transport [GO:0034220]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of pharyngeal pumping [GO:0043051]; response to anesthetic [GO:0072347] comp138206_c0_seq2,2198,39.8089,0.76448295,0,0,,1.00E-22,Q6AY22,Spermatogenesis-associated protein 1,Spermatogenesis-associated protein 1,,,PF15743;,8.00E-66,CHOYP_LOC100374267.5.5,,,,,,,SPAT1_RAT,Rattus norvegicus (Rat), comp138206_c0_seq7,2033,40.1377,0.80011397,20,9,,1.00E-22,Q6AY22,Spermatogenesis-associated protein 1,Spermatogenesis-associated protein 1,,,PF15743;,8.00E-66,CHOYP_LOC100374267.5.5,,,,,,,SPAT1_RAT,Rattus norvegicus (Rat), comp138206_c0_seq8,1196,46.6555,0.83106889,0,0,,,,,,,,,,,1.00E-19,ruditapes2_c1537,,,,,,, comp138207_c0_seq1,2366,43.153,0.35566016,1299,7970,,9.00E-121,O88874,Cyclin-K,Cyclin-K,GO:0008353; GO:0051301; GO:0004693; GO:0001701; GO:0007067; GO:0071157; GO:0000079; GO:0006355; GO:0006351,"RNA polymerase II carboxy-terminal domain kinase activity; cell division; cyclin-dependent protein serine/threonine kinase activity; in utero embryonic development; mitosis; negative regulation of cell cycle arrest; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02984;PF00134;,3.00E-115,CHOYP_LOC100123595.1.2,,,,,,,CCNK_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; in utero embryonic development [GO:0001701]; mitotic nuclear division [GO:0007067]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp138209_c0_seq1,1375,35.9273,0.56460114,672,5305,,8.00E-75,Q5M8Y1,Probable signal peptidase complex subunit 2 (EC 3.4.-.-) (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit),Probable signal peptidase complex subunit 2 (EC 3.4.-.-) (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit),GO:0016021; GO:0008233; GO:0006508; GO:0005787; GO:0006465,integral to membrane; peptidase activity; proteolysis; signal peptidase complex; signal peptide processing,PF06703;,2.00E-70,CHOYP_LOC101063838.1.1,,,,,,,SPCS2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465] comp138212_c4_seq1,1123,41.3179,0.87722823,4,505,female>male,1.00E-90,P23416,Glycine receptor subunit alpha-2,Glycine receptor subunit alpha-2,GO:0030054; GO:0034707; GO:0016934; GO:0016594; GO:0005887; GO:0007218; GO:0045211; GO:0007416; GO:0022824,cell junction; chloride channel complex; extracellular-glycine-gated chloride channel activity; glycine binding; integral to plasma membrane; neuropeptide signaling pathway; postsynaptic membrane; synapse assembly; transmitter-gated ion channel activity,PF02931;PF02932;,9.00E-43,CHOYP_LOC100533289.4.6,,,,,,,GLRA2_HUMAN,Homo sapiens (Human),"cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; neuropeptide signaling pathway [GO:0007218]; spinal cord development [GO:0021510]; synapse assembly [GO:0007416]; synaptic transmission, glycinergic [GO:0060012]" comp138215_c0_seq1,1390,43.0935,0.78459948,10,633,,4.00E-152,Q0P4F7,"Acyl-CoA synthetase family member 2, mitochondrial (EC 6.2.1.-)","Acyl-CoA synthetase family member 2, mitochondrial (EC 6.2.1.-)",GO:0005524; GO:0006631; GO:0016874; GO:0005739,ATP binding; fatty acid metabolic process; ligase activity; mitochondrion,PF00501;PF13193;,8.00E-83,CHOYP_LOC100374370.1.1,,,,,,,ACSF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid metabolic process [GO:0006631] comp138216_c2_seq1,1122,36.9875,0.60143018,83,373,,1.00E-46,Q8IYD8,Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0071821; GO:0043240; GO:0003682; GO:0004518; GO:0090305; GO:0031297; GO:0000712,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; FANCM-MHF complex; Fanconi anaemia nuclear complex; chromatin binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; replication fork processing; resolution of meiotic recombination intermediates,PF02732;PF16783;PF00271;PF04851;,,,,,,,,,FANCM_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp138221_c0_seq2,614,41.6938,0.56724002,8,14,,4.00E-49,P53809,Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2),Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2),GO:0005829; GO:0031210; GO:0008525,cytosol; phosphatidylcholine binding; phosphatidylcholine transporter activity,PF01852;,1.00E-43,CHOYP_BRAFLDRAFT_270293.1.3,,,,,,,PPCT_RAT,Rattus norvegicus (Rat),phospholipid transport [GO:0015914] comp138223_c0_seq1,1191,39.4626,0.39371725,12,8,,9.00E-18,Q9BQI6,Ankyrin repeat domain-containing protein 32 (BRCT domain-containing protein 1),SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1),GO:0005813; GO:0005634,centrosome; nucleus,PF12796;PF16770;,,,,,,,,,ANR32_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166] comp138223_c0_seq2,1337,38.5939,0.38950196,1,12,,5.00E-08,O95271,Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I),Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I),GO:0005794; GO:0000139; GO:0003950; GO:0016055; GO:0051301; GO:0000775; GO:0051028; GO:0007067; GO:0007052; GO:0043392; GO:0000784; GO:0031965; GO:0005643; GO:0018105; GO:0018107; GO:0000242; GO:0090263; GO:0032212; GO:0045944; GO:0070213; GO:0070198; GO:0070212; GO:0000209; GO:0015031; GO:0051225; GO:0000922; GO:0008270,"Golgi apparatus; Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; cell division; chromosome, centromeric region; mRNA transport; mitosis; mitotic spindle organization; negative regulation of DNA binding; nuclear chromosome, telomeric region; nuclear membrane; nuclear pore; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; pericentriolar material; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of telomere maintenance via telomerase; positive regulation of transcription from RNA polymerase II promoter; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein poly-ADP-ribosylation; protein polyubiquitination; protein transport; spindle assembly; spindle pole; zinc ion binding",PF00023;PF12796;PF13606;PF00644;PF07647;,,,,,,,,,TNKS1_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; regulation of telomere maintenance via telomerase [GO:0032210]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]" comp138223_c1_seq3,555,41.8018,0.24791995,1,10,,2.00E-06,Q9BQI6,Ankyrin repeat domain-containing protein 32 (BRCT domain-containing protein 1),SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1),GO:0005813; GO:0005634,centrosome; nucleus,PF12796;PF16770;,,,,,,,,,ANR32_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166] comp138224_c0_seq1,902,41.6851,0.51149944,0,0,,7.00E-15,O95639,Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog),Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog),GO:0003723; GO:0005847; GO:0006397; GO:0005739; GO:0046778; GO:0019058; GO:0008270,RNA binding; mRNA cleavage and polyadenylation specificity factor complex; mRNA processing; mitochondrion; modification by virus of host mRNA processing; viral life cycle; zinc ion binding,PF00642;PF00098;,1.00E-34,CHOYP_LOC101168697.2.2,,,,,,,CPSF4_HUMAN,Homo sapiens (Human),"modification by virus of host mRNA processing [GO:0046778]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp138224_c0_seq2,2585,39.6518,0.45355281,3,21,,4.00E-47,Q3ED78,Zinc finger CCCH domain-containing protein 7 (AtC3H7) (EC 3.1.-.-) (AtSmicl),Zinc finger CCCH domain-containing protein 7 (AtC3H7) (EC 3.1.-.-) (AtSmicl),GO:0003677; GO:0003723; GO:0046872; GO:0004518; GO:0090305,DNA binding; RNA binding; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis,,,,,,,,,,C3H7_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138224_c0_seq3,2525,39.7624,0.45185507,0,17,,3.00E-62,Q8IXZ2,Zinc finger CCCH domain-containing protein 3,Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor),GO:0006378; GO:0046872; GO:0005634; GO:0016973; GO:0010793,mRNA polyadenylation; metal ion binding; nucleus; poly(A)+ mRNA export from nucleus; regulation of mRNA export from nucleus,PF00642;,,,,,,,,,ZC3H3_HUMAN,Homo sapiens (Human),mRNA polyadenylation [GO:0006378]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of activin receptor signaling pathway [GO:0032927]; regulation of mRNA export from nucleus [GO:0010793] comp138224_c0_seq4,945,39.7884,0.5097133,12,6,,1.00E-26,O74823,Zinc finger CCCH domain-containing protein C337.12,Zinc finger CCCH domain-containing protein C337.12,GO:0046872; GO:0033621; GO:0005634; GO:0016973,"metal ion binding; nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts; nucleus; poly(A)+ mRNA export from nucleus",PF00642;,1.00E-34,CHOYP_LOC101168697.2.2,,,,,,,YBJC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts [GO:0033621]" comp138232_c1_seq3,1237,41.3905,0.30374797,9,176,,8.00E-122,P45478,Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1),Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1),GO:0005794; GO:0006309; GO:0030424; GO:0007420; GO:0051186; GO:0051181; GO:0005829; GO:0005576; GO:0016042; GO:0007042; GO:0005764; GO:0045121; GO:0031579; GO:0030308; GO:0043524; GO:0005634; GO:0008474; GO:0016290; GO:0006907; GO:0048549; GO:0048260; GO:0002084; GO:0015031; GO:0006898; GO:0008021,Golgi apparatus; apoptotic DNA fragmentation; axon; brain development; cofactor metabolic process; cofactor transport; cytosol; extracellular region; lipid catabolic process; lysosomal lumen acidification; lysosome; membrane raft; membrane raft organization; negative regulation of cell growth; negative regulation of neuron apoptotic process; nucleus; palmitoyl-(protein) hydrolase activity; palmitoyl-CoA hydrolase activity; pinocytosis; positive regulation of pinocytosis; positive regulation of receptor-mediated endocytosis; protein depalmitoylation; protein transport; receptor-mediated endocytosis; synaptic vesicle,PF02089;,1.00E-73,CHOYP_BRAFLDRAFT_128749.1.1,,,,,,,PPT1_BOVIN,Bos taurus (Bovine),brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; cofactor metabolic process [GO:0051186]; cofactor transport [GO:0051181]; lipid catabolic process [GO:0016042]; lysosomal lumen acidification [GO:0007042]; membrane raft organization [GO:0031579]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; pinocytosis [GO:0006907]; positive regulation of pinocytosis [GO:0048549]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein depalmitoylation [GO:0002084]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp138235_c0_seq2,3651,35.0589,0.54622941,335,58,,,,,,,,,0,CHOYP_BRAFLDRAFT_123537.1.2,,,,,,,,, comp138235_c0_seq3,3186,34.8085,0.58421558,977,161,,2.00E-154,Q9UIF3,Tektin-2 (Tektin-t) (Testicular tektin) (Testicular tektin B1-like protein) (TEKTB1) (Tektin-B1),Tektin-2 (Tektin-t) (Testicular tektin) (Testicular tektin B1-like protein) (TEKTB1) (Tektin-B1),GO:0030030; GO:0001539; GO:0035085; GO:0005874; GO:0000226; GO:0030317,cell projection organization; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule cytoskeleton organization; sperm motility,,0,CHOYP_BRAFLDRAFT_123537.2.2,0,ruditapes_c7637,,,,,TEKT2_HUMAN,Homo sapiens (Human),inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp138238_c0_seq1,4368,39.1255,0.79380605,19,275,,5.00E-12,Q25490,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF06448;PF09172;PF01347;PF00094;,,,,,,,,,APLP_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),Wnt signaling pathway [GO:0016055] comp138238_c0_seq2,4357,39.0406,0.7991776,0,76,,5.00E-23,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,,,7.00E-49,ruditapes2_lrc3549,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp138238_c0_seq3,4389,39.0066,0.78872807,2,222,,4.00E-12,Q25490,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF06448;PF09172;PF01347;PF00094;,,,,,,,,,APLP_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),Wnt signaling pathway [GO:0016055] comp138238_c0_seq4,4400,39.0455,0.79128804,3,49,,5.00E-23,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,,,3.00E-66,ruditapes2_lrc3330,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp138239_c0_seq1,1686,46.382,0.68451595,0,0,,4.00E-30,Q8BIE6,FERM domain-containing protein 4A,FERM domain-containing protein 4A,GO:0005737; GO:0005856; GO:0090162; GO:0005923,cytoplasm; cytoskeleton; establishment of epithelial cell polarity; tight junction,PF11819;PF09380;PF00373;PF09379;,,,,,,,,,FRM4A_MOUSE,Mus musculus (Mouse),establishment of epithelial cell polarity [GO:0090162] comp138239_c0_seq3,955,42.0942,0.49702966,0,5,,2.00E-120,Q8BIE6,FERM domain-containing protein 4A,FERM domain-containing protein 4A,GO:0005737; GO:0005856; GO:0090162; GO:0005923,cytoplasm; cytoskeleton; establishment of epithelial cell polarity; tight junction,PF11819;PF09380;PF00373;PF09379;,3.00E-93,CHOYP_FRM4B.1.1,,,,,,,FRM4A_MOUSE,Mus musculus (Mouse),establishment of epithelial cell polarity [GO:0090162] comp138239_c0_seq4,1372,44.4606,0.66429091,0,0,,7.00E-19,Q91VS8,"FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)","FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)",GO:0030676; GO:0016601; GO:0031532; GO:0007155; GO:0005856; GO:0005829; GO:0019898; GO:0016322; GO:0030316; GO:0005543; GO:0071800; GO:0035023; GO:0033623; GO:0071526,Rac guanyl-nucleotide exchange factor activity; Rac protein signal transduction; actin cytoskeleton reorganization; cell adhesion; cytoskeleton; cytosol; extrinsic to membrane; neuron remodeling; osteoclast differentiation; phospholipid binding; podosome assembly; regulation of Rho protein signal transduction; regulation of integrin activation; semaphorin-plexin signaling pathway,PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;,,,,,,,,,FARP2_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526] comp138239_c0_seq5,2614,46.1744,0.66774033,0,0,,2.00E-35,Q8HZQ5,Ezrin (Cytovillin) (Villin-2) (p81),Ezrin (Cytovillin) (Villin-2) (p81),GO:0005884; GO:0051015; GO:0051017; GO:0016324; GO:0016323; GO:0050839; GO:0005938; GO:0019898; GO:0031528; GO:0008360; GO:0032587,actin filament; actin filament binding; actin filament bundle assembly; apical plasma membrane; basolateral plasma membrane; cell adhesion molecule binding; cell cortex; extrinsic to membrane; microvillus membrane; regulation of cell shape; ruffle membrane,PF00769;PF09380;PF00373;PF09379;,3.00E-180,CHOYP_LOC100369109.1.2,,,,,,,EZRI_RABIT,Oryctolagus cuniculus (Rabbit),actin filament bundle assembly [GO:0051017]; regulation of cell shape [GO:0008360] comp138240_c1_seq1,3579,43.5317,0.4853708,6524,17497,,1.00E-172,P36956,Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1],Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1],GO:0012507; GO:0000139; GO:0007568; GO:0044255; GO:0009267; GO:0008203; GO:0003682; GO:0005829; GO:0005783; GO:0005789; GO:0008286; GO:0016021; GO:0008610; GO:0030324; GO:0046676; GO:0000122; GO:0005635; GO:0005654; GO:0005634; GO:0045542; GO:0031065; GO:0045944; GO:0010867; GO:0043234; GO:0019217; GO:0003062; GO:0006357; GO:0051591; GO:0042493; GO:0070542; GO:0032094; GO:0033762; GO:0009749; GO:0032570; GO:0032526; GO:0043565; GO:0003700; GO:0044281; GO:0032810; GO:0006351,"ER to Golgi transport vesicle membrane; Golgi membrane; aging; cellular lipid metabolic process; cellular response to starvation; cholesterol metabolic process; chromatin binding; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; insulin receptor signaling pathway; integral to membrane; lipid biosynthetic process; lung development; negative regulation of insulin secretion; negative regulation of transcription from RNA polymerase II promoter; nuclear envelope; nucleoplasm; nucleus; positive regulation of cholesterol biosynthetic process; positive regulation of histone deacetylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of triglyceride biosynthetic process; protein complex; regulation of fatty acid metabolic process; regulation of heart rate by chemical signal; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to drug; response to fatty acid; response to food; response to glucagon stimulus; response to glucose stimulus; response to progesterone stimulus; response to retinoic acid; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; small molecule metabolic process; sterol response element binding; transcription, DNA-dependent",PF00010;,4.00E-34,CHOYP_BRAFLDRAFT_117231.1.1,4.00E-57,ruditapes2_c1794,,,,,SRBP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; cholesterol metabolic process [GO:0008203]; circadian rhythm [GO:0007623]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; lipid biosynthetic process [GO:0008610]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of insulin secretion [GO:0046676]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of fatty acid metabolic process [GO:0019217]; regulation of heart rate by chemical signal [GO:0003062]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526] comp138241_c1_seq1,988,40.1822,0.37669532,36,137,,4.00E-09,Q91WC1,Protection of telomeres protein 1 (mPot1) (POT1-like telomere end-binding protein),Protection of telomeres protein 1 (mPot1) (POT1-like telomere end-binding protein),GO:0000783; GO:0005654; GO:0043047; GO:0007004,nuclear telomere cap complex; nucleoplasm; single-stranded telomeric DNA binding; telomere maintenance via telomerase,PF02765;PF16686;,,,,,,,,,POTE1_MOUSE,Mus musculus (Mouse),chromosome organization [GO:0051276]; DNA duplex unwinding [GO:0032508]; establishment of protein localization to telomere [GO:0070200]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA strand elongation [GO:0060383]; positive regulation of helicase activity [GO:0051096]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004] comp138241_c1_seq3,364,42.033,0.25034482,5,19,,2.00E-12,P62597,Protection of telomeres protein 1 (cPot1) (POT1-like telomere end-binding protein),Protection of telomeres protein 1 (cPot1) (POT1-like telomere end-binding protein),GO:0000781; GO:0000784; GO:0005654; GO:0043047; GO:0007004,"chromosome, telomeric region; nuclear chromosome, telomeric region; nucleoplasm; single-stranded telomeric DNA binding; telomere maintenance via telomerase",PF02765;PF16686;,,,,,,,,,POTE1_CHICK,Gallus gallus (Chicken),negative regulation of telomerase activity [GO:0051974]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] comp138243_c2_seq1,2642,34.8978,0.4252897,0,0,,1.00E-08,Q41005,Serine carboxypeptidase-like (EC 3.4.16.-) (Fragment),Serine carboxypeptidase-like (EC 3.4.16.-) (Fragment),GO:0006508; GO:0004185,proteolysis; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,CBPX_PEA,Pisum sativum (Garden pea), comp138243_c2_seq2,3368,36.728,0.45159438,0,0,,3.00E-130,Q920A6,Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1),Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1),GO:0005829; GO:0005576; GO:0006508; GO:0042573; GO:0004185,cytosol; extracellular region; proteolysis; retinoic acid metabolic process; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,RISC_RAT,Rattus norvegicus (Rat),negative regulation of blood pressure [GO:0045776]; positive regulation of vasodilation [GO:0045909]; proteolysis involved in cellular protein catabolic process [GO:0051603]; retinoic acid metabolic process [GO:0042573] comp138243_c2_seq4,2359,40.2713,0.45403102,0,0,,1.00E-133,Q920A6,Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1),Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1),GO:0005829; GO:0005576; GO:0006508; GO:0042573; GO:0004185,cytosol; extracellular region; proteolysis; retinoic acid metabolic process; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,RISC_RAT,Rattus norvegicus (Rat),negative regulation of blood pressure [GO:0045776]; positive regulation of vasodilation [GO:0045909]; proteolysis involved in cellular protein catabolic process [GO:0051603]; retinoic acid metabolic process [GO:0042573] comp138243_c2_seq5,2722,34.313,0.42677699,0,0,,1.00E-08,Q41005,Serine carboxypeptidase-like (EC 3.4.16.-) (Fragment),Serine carboxypeptidase-like (EC 3.4.16.-) (Fragment),GO:0006508; GO:0004185,proteolysis; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,CBPX_PEA,Pisum sativum (Garden pea), comp138243_c2_seq8,3395,36.7599,0.44756383,0,93,,3.00E-130,Q920A6,Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1),Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1),GO:0005829; GO:0005576; GO:0006508; GO:0042573; GO:0004185,cytosol; extracellular region; proteolysis; retinoic acid metabolic process; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,RISC_RAT,Rattus norvegicus (Rat),negative regulation of blood pressure [GO:0045776]; positive regulation of vasodilation [GO:0045909]; proteolysis involved in cellular protein catabolic process [GO:0051603]; retinoic acid metabolic process [GO:0042573] comp138244_c0_seq1,437,42.7918,0.46540976,2,33,,6.00E-49,Q9JHW4,"Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB)","Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB)",GO:0005525; GO:0003924; GO:0005739; GO:0005634; GO:0030529; GO:0043021; GO:0001514; GO:0035368; GO:0000049; GO:0003746,GTP binding; GTPase activity; mitochondrion; nucleus; ribonucleoprotein complex; ribonucleoprotein complex binding; selenocysteine incorporation; selenocysteine insertion sequence binding; tRNA binding; translation elongation factor activity,PF03144;,,,,,,,,,SELB_MOUSE,Mus musculus (Mouse),selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259] comp138244_c1_seq2,2773,37.4324,0.42299644,0,0,,6.00E-08,A1T056,Elongation factor Tu (EF-Tu),Elongation factor Tu (EF-Tu),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,,,,,,,,,EFTU_PSYIN,Psychromonas ingrahamii (strain 37), comp138244_c1_seq5,1488,42.1371,0.35077654,0,0,,5.00E-145,Q9JHW4,"Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB)","Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB)",GO:0005525; GO:0003924; GO:0005739; GO:0005634; GO:0030529; GO:0043021; GO:0001514; GO:0035368; GO:0000049; GO:0003746,GTP binding; GTPase activity; mitochondrion; nucleus; ribonucleoprotein complex; ribonucleoprotein complex binding; selenocysteine incorporation; selenocysteine insertion sequence binding; tRNA binding; translation elongation factor activity,PF03144;,1.00E-54,CHOYP_LOC100375943.1.1,,,,,,,SELB_MOUSE,Mus musculus (Mouse),selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259] comp138245_c0_seq1,1631,40.5273,0.52356617,0,0,,1.00E-24,Q7X8C5,Wall-associated receptor kinase-like 2 (EC 2.7.11.-),Wall-associated receptor kinase-like 2 (EC 2.7.11.-),GO:0005524; GO:0005509; GO:0016021; GO:0030247; GO:0046777; GO:0004674,ATP binding; calcium ion binding; integral to membrane; polysaccharide binding; protein autophosphorylation; protein serine/threonine kinase activity,PF13947;PF07714;PF08488;,,,,,,,,,WAKLB_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell surface receptor signaling pathway [GO:0007166]; protein autophosphorylation [GO:0046777] comp138245_c0_seq10,2305,39.0022,0.60595292,0,0,,3.00E-07,Q8W490,Serine/threonine-protein kinase PEPKR2 (EC 2.7.11.-) (Protein PHOSPHOENOLPYRUVATE CARBOXYLASE-RELATED KINASE 2),Serine/threonine-protein kinase PEPKR2 (EC 2.7.11.-) (Protein PHOSPHOENOLPYRUVATE CARBOXYLASE-RELATED KINASE 2),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PEPK2_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] comp138245_c0_seq2,1255,39.761,0.52520217,0,0,,5.00E-10,O64774,G-type lectin S-receptor-like serine/threonine-protein kinase At1g61460 (EC 2.7.11.1),G-type lectin S-receptor-like serine/threonine-protein kinase At1g61460 (EC 2.7.11.1),GO:0005524; GO:0005516; GO:0016021; GO:0005886; GO:0004674; GO:0048544,ATP binding; calmodulin binding; integral to membrane; plasma membrane; protein serine/threonine kinase activity; recognition of pollen,PF01453;PF11883;PF08276;PF07714;PF00954;,,,,,,,,,Y1146_ARATH,Arabidopsis thaliana (Mouse-ear cress),innate immune response [GO:0045087]; protein phosphorylation [GO:0006468]; recognition of pollen [GO:0048544] comp138245_c0_seq6,3159,39.6645,0.56979182,0,0,,2.00E-13,O80963,Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2),Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2),GO:0005524; GO:0016021; GO:0042803; GO:0004672; GO:0004674,ATP binding; integral to membrane; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity,PF07714;,,,,,,,,,ACCR2_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138245_c0_seq7,1571,40.6111,0.54121071,0,0,,7.00E-14,O80963,Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2),Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2),GO:0005524; GO:0016021; GO:0042803; GO:0004672; GO:0004674,ATP binding; integral to membrane; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity,PF07714;,,,,,,,,,ACCR2_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138245_c0_seq8,3219,39.6396,0.55992354,0,0,,8.00E-24,Q7X8C5,Wall-associated receptor kinase-like 2 (EC 2.7.11.-),Wall-associated receptor kinase-like 2 (EC 2.7.11.-),GO:0005524; GO:0005509; GO:0016021; GO:0030247; GO:0046777; GO:0004674,ATP binding; calcium ion binding; integral to membrane; polysaccharide binding; protein autophosphorylation; protein serine/threonine kinase activity,PF13947;PF07714;PF08488;,,,,,,,,,WAKLB_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell surface receptor signaling pathway [GO:0007166]; protein autophosphorylation [GO:0046777] comp138245_c0_seq9,717,39.6095,0.6077789,0,0,,1.00E-07,Q54C18,Probable serine/threonine-protein kinase DDB_G0293276 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0293276 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,Y9452_DICDI,Dictyostelium discoideum (Slime mold),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] comp138250_c0_seq1,1851,41.383,0.40802793,103,98,,3.00E-82,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,5.00E-93,CHOYP_PHUM_PHUM216240.1.1,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp138250_c0_seq2,1229,45.0773,0.51657601,1,7,,1.00E-84,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,,,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp138254_c1_seq1,1849,39.9676,0.38183706,170,872,,0,Q0VD48,Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6),Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6),GO:0005524; GO:0016887; GO:0007049; GO:0051301; GO:0005829; GO:0005769; GO:0007032; GO:0032510; GO:0032367; GO:0031902; GO:0005764; GO:0005634; GO:0006813; GO:0015031; GO:0033993; GO:0005774,ATP binding; ATPase activity; cell cycle; cell division; cytosol; early endosome; endosome organization; endosome to lysosome transport via multivesicular body sorting pathway; intracellular cholesterol transport; late endosome membrane; lysosome; nucleus; potassium ion transport; protein transport; response to lipid; vacuolar membrane,PF00004;PF04212;PF09336;,0,CHOYP_VPS4B.2.2,9.00E-56,ruditapes_c26156,,,,,VPS4B_BOVIN,Bos taurus (Bovine),cell separation after cytokinesis [GO:0000920]; cholesterol transport [GO:0030301]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; late endosomal microautophagy [GO:0061738]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of mitotic spindle assembly [GO:1901673]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076] comp138255_c0_seq1,2041,40.1274,0.31874077,0,0,,5.00E-13,A9MHZ1,Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),GO:0005524; GO:0005737; GO:0016260; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteine biosynthetic process; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,,,,,,,,,SYS_SALAR,Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980),selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp138255_c0_seq2,2041,40.1764,0.31802289,0,0,,8.00E-14,Q5FIN5,Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),GO:0005524; GO:0005737; GO:0016260; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteine biosynthetic process; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,,,,,,,,,SYS_LACAC,Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM),selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp138255_c0_seq3,2029,40.2661,0.31856214,0,0,,5.00E-26,Q9N0F3,"Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)","Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)",GO:0005524; GO:0005759; GO:0005739; GO:0097056; GO:0004828; GO:0006434,ATP binding; mitochondrial matrix; mitochondrion; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF00587;,,,,,,,,,SYSM_BOVIN,Bos taurus (Bovine),selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp138255_c0_seq4,2017,40.2578,0.32055238,0,0,,4.00E-12,B8H9Q1,Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),GO:0005524; GO:0005737; GO:0016260; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteine biosynthetic process; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,,,,,,,,,SYS_ARTCA,Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter chlorophenolicus),selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp138255_c0_seq5,2029,40.2169,0.31928287,0,0,,8.00E-14,Q5FIN5,Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),GO:0005524; GO:0005737; GO:0016260; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteine biosynthetic process; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,,,,,,,,,SYS_LACAC,Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM),selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp138255_c0_seq6,2005,40.3491,0.3210984,0,0,,5.00E-26,Q9N0F3,"Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)","Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)",GO:0005524; GO:0005759; GO:0005739; GO:0097056; GO:0004828; GO:0006434,ATP binding; mitochondrial matrix; mitochondrion; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF00587;,,,,,,,,,SYSM_BOVIN,Bos taurus (Bovine),selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp138257_c3_seq1,1300,36.6154,0.25318912,80,466,,1.00E-57,Q5VVH5,Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1-binding protein 1),Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1-binding protein 1),GO:0007249; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"I-kappaB kinase/NF-kappaB cascade; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04402;,4.00E-29,CHOYP_BRAFLDRAFT_122970.1.1,,,,,,,IKBP1_HUMAN,Homo sapiens (Human),"I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138258_c2_seq1,218,47.2477,0.96392873,6,12,,6.00E-21,O94768,Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2),Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2),GO:0005524; GO:0015629; GO:0006915; GO:0005793; GO:0007243; GO:0005634; GO:0005886; GO:2000271; GO:0046777; GO:0004674,ATP binding; actin cytoskeleton; apoptotic process; endoplasmic reticulum-Golgi intermediate compartment; intracellular protein kinase cascade; nucleus; plasma membrane; positive regulation of fibroblast apoptotic process; protein autophosphorylation; protein serine/threonine kinase activity,PF00069;,4.00E-20,CHOYP_STK17A.1.1,,,,,,,ST17B_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of fibroblast apoptotic process [GO:2000271]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp138259_c1_seq1,2141,42.6903,0.45766351,344,1569,,4.00E-29,Q5R1T0,Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150),Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150),GO:0033186; GO:0006281; GO:0006260; GO:0007049; GO:0031497; GO:0005634; GO:0006355; GO:0006351,"CAF-1 complex; DNA repair; DNA replication; cell cycle; chromatin assembly; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15539;PF15557;PF12253;,7.00E-35,CHOYP_LOC100120677.1.1,,,,,,,CAF1A_CHICK,Gallus gallus (Chicken),cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334] comp138262_c0_seq1,916,42.1397,0.37182755,82,139,,1.00E-30,Q6ZSB9,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp138262_c0_seq2,1418,44.0762,0.53973258,65,78,,2.00E-17,P98182,Zinc finger protein 200,Zinc finger protein 200,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN200_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp138264_c0_seq2,1119,31.1886,0.94851024,50,7,,3.00E-13,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138264_c0_seq4,2390,30.795,0.98858861,855,137,,9.00E-17,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp138269_c0_seq2,2680,34.8881,0.5669984,142,1093,,6.00E-09,Q07230,Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29),Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29),GO:0003677; GO:0030154; GO:0046872; GO:0007275; GO:0005634; GO:0003700; GO:0007283; GO:0006351,"DNA binding; cell differentiation; metal ion binding; multicellular organismal development; nucleus; sequence-specific DNA binding transcription factor activity; spermatogenesis; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSCA2_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp138269_c1_seq2,1270,32.0472,0.46380119,0,0,,9.00E-07,Q5RAU9,Zinc finger protein 131,Zinc finger protein 131,GO:0003677; GO:0046872; GO:0005634; GO:0000981; GO:0006366,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter,PF00651;,,,,,,,,,ZN131_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"transcription, DNA-templated [GO:0006351]" comp138270_c0_seq1,1856,44.3427,0.41674652,988,5557,,1.00E-117,Q15428,Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62),Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62),GO:0071013; GO:0000389; GO:0003676; GO:0005654; GO:0030532; GO:0008270,catalytic step 2 spliceosome; mRNA 3'-splice site recognition; nucleic acid binding; nucleoplasm; small nuclear ribonucleoprotein complex; zinc ion binding,PF16835;,1.00E-151,CHOYP_PHUM_PHUM544530.1.1,,,,,,,SF3A2_HUMAN,Homo sapiens (Human),"mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of neuron projection development [GO:0010976]; RNA splicing [GO:0008380]" comp138270_c0_seq2,668,44.1617,0.56334333,49,378,,,,,,,,,9.00E-34,CHOYP_SF3A2.1.1,,,,,,,,, comp138271_c0_seq1,1555,37.7492,0.49865896,59,947,,1.00E-91,O94766,"Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)","Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)",GO:0000139; GO:0005975; GO:0030204; GO:0050650; GO:0005801; GO:0050651; GO:0015018; GO:0015012; GO:0016021; GO:0030145; GO:0006486,Golgi membrane; carbohydrate metabolic process; chondroitin sulfate metabolic process; chondroitin sulfate proteoglycan biosynthetic process; cis-Golgi network; dermatan sulfate proteoglycan biosynthetic process; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to membrane; manganese ion binding; protein glycosylation,PF03360;,3.00E-32,CHOYP_BRAFLDRAFT_92974.1.1,,,,,,,B3GA3_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; chondroitin sulfate metabolic process [GO:0030204]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] comp138271_c0_seq2,771,36.8353,0.27342689,0,8,,6.00E-32,O94766,"Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)","Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)",GO:0000139; GO:0005975; GO:0030204; GO:0050650; GO:0005801; GO:0050651; GO:0015018; GO:0015012; GO:0016021; GO:0030145; GO:0006486,Golgi membrane; carbohydrate metabolic process; chondroitin sulfate metabolic process; chondroitin sulfate proteoglycan biosynthetic process; cis-Golgi network; dermatan sulfate proteoglycan biosynthetic process; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to membrane; manganese ion binding; protein glycosylation,PF03360;,,,,,,,,,B3GA3_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; chondroitin sulfate metabolic process [GO:0030204]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] comp138272_c2_seq1,2034,42.8712,1.02769152,29,466,,0,P17276,Protein henna (EC 1.14.16.1) (EC 1.14.16.4) (Phe-4-monooxygenase) (Phenylalanine-4-hydroxylase) (PAH) (Tryptophan 5-hydroxylase) (TRH) (Tryptophan 5-monooxygenase),Protein henna (EC 1.14.16.1) (EC 1.14.16.4) (Phe-4-monooxygenase) (Phenylalanine-4-hydroxylase) (PAH) (Tryptophan 5-hydroxylase) (TRH) (Tryptophan 5-monooxygenase),GO:0006559; GO:0005506; GO:0005811; GO:0007616; GO:0006909; GO:0004505; GO:0042427; GO:0004510,L-phenylalanine catabolic process; iron ion binding; lipid particle; long-term memory; phagocytosis; phenylalanine 4-monooxygenase activity; serotonin biosynthetic process; tryptophan 5-monooxygenase activity,PF00351;,4.00E-126,CHOYP_BRAFLDRAFT_115951.1.1,,,,,,,PH4H_DROME,Drosophila melanogaster (Fruit fly),eye pigment biosynthetic process [GO:0006726]; long-term memory [GO:0007616]; L-phenylalanine catabolic process [GO:0006559]; phagocytosis [GO:0006909]; serotonin biosynthetic process [GO:0042427] comp138273_c0_seq1,2445,36.1554,0.57876758,1844,90,,3.00E-155,Q2TA16,Coiled-coil domain-containing protein 65,Coiled-coil domain-containing protein 65,,,,0,CHOYP_LOC100369421.1.2,,,,,,,CCD65_BOVIN,Bos taurus (Bovine), comp138277_c1_seq2,1837,43.0049,0.74617251,0,0,,2.00E-126,A8WHP3,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,,,,,,,,,SC5A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),sodium ion transport [GO:0006814] comp138277_c1_seq3,1342,45.38,0.77188973,0,0,,7.00E-28,P96169,Sodium/glucose cotransporter (Na(+)/glucose symporter),Sodium/glucose cotransporter (Na(+)/glucose symporter),GO:0008643; GO:0016021; GO:0005886; GO:0006814; GO:0015293,carbohydrate transport; integral to membrane; plasma membrane; sodium ion transport; symporter activity,PF00474;,3.00E-49,CHOYP_SC5A9.3.5,,,,,,,SGLT_VIBPH,Vibrio parahaemolyticus,carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp138277_c1_seq4,1870,43.369,0.77844832,4,8,,1.00E-141,A8WHP3,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,4.00E-63,CHOYP_SC5A9.1.5,,,,,,,SC5A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),sodium ion transport [GO:0006814] comp138277_c1_seq6,999,43.9439,0.79318774,0,0,,7.00E-06,P45174,Sodium/proline symporter (Proline permease),Sodium/proline symporter (Proline permease),GO:0016021; GO:0005886; GO:0005298; GO:0031402,integral to membrane; plasma membrane; proline:sodium symporter activity; sodium ion binding,PF00474;,,,,,,,,,PUTP_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),proline transmembrane transport [GO:0035524] comp138277_c1_seq7,1375,45.9636,0.80386827,0,0,,2.00E-112,P26430,Sodium/nucleoside cotransporter (Na(+)/glucose cotransporter 2) (Solute carrier family 5 member 2),Sodium/nucleoside cotransporter (Na(+)/glucose cotransporter 2) (Solute carrier family 5 member 2),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00474;,3.00E-63,CHOYP_SC5A9.1.5,,,,,,,SC5A2_RABIT,Oryctolagus cuniculus (Rabbit),sodium ion transport [GO:0006814] comp138279_c0_seq1,885,43.8418,0.40229752,0,0,,4.00E-64,Q9D2V7,Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog),Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog),GO:0005794; GO:0000139; GO:0016023; GO:0005829; GO:0016021,Golgi apparatus; Golgi membrane; cytoplasmic membrane-bounded vesicle; cytosol; integral to membrane,PF08953;PF00400;,,,,,,,,,CORO7_MOUSE,Mus musculus (Mouse),actin filament polymerization [GO:0030041]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] comp138279_c0_seq3,2156,40.8627,0.37836256,40,253,,5.00E-145,P57737,Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog),Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog),GO:0005794; GO:0000139; GO:0016023; GO:0005829; GO:0016021,Golgi apparatus; Golgi membrane; cytoplasmic membrane-bounded vesicle; cytosol; integral to membrane,PF08953;PF00400;,2.00E-60,CHOYP_BRAFLDRAFT_117106.1.1,,,,,,,CORO7_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] comp138279_c0_seq4,1100,44.8182,0.39966373,2,0,,7.00E-11,Q00808,Vegetative incompatibility protein HET-E-1,Vegetative incompatibility protein HET-E-1,GO:0005525,GTP binding,PF06985;PF00400;,2.00E-31,CHOYP_BRAFLDRAFT_117106.1.1,,,,,,,HETE1_PODAS,Podospora anserina (Pleurage anserina), comp138279_c0_seq6,285,42.807,0.4631636,0,0,,2.00E-06,Q4I7X1,Polyadenylation factor subunit 2,Polyadenylation factor subunit 2,GO:0051301; GO:0007059; GO:0006397; GO:0007067; GO:0005634,cell division; chromosome segregation; mRNA processing; mitosis; nucleus,PF00400;,,,,,,,,,PFS2_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),chromosome segregation [GO:0007059]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp138282_c0_seq1,1360,41.3971,0.403379,30,407,,9.00E-123,B4NWI1,Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GE19290 (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain],Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GE19290 (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain],GO:0003948; GO:0005764; GO:0008233; GO:0006517; GO:0006508,N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; lysosome; peptidase activity; protein deglycosylation; proteolysis,PF01112;,7.00E-14,CHOYP_ASPG.2.2,,,,,,,ASPG1_DROYA,Drosophila yakuba (Fruit fly),protein deglycosylation [GO:0006517] comp138282_c0_seq2,752,38.8298,0.3291889,14,65,,,,,,,,,2.00E-17,CHOYP_LOC100697862.1.1,,,,,,,,, comp138283_c0_seq1,916,41.4847,0.71322307,0,0,,4.00E-26,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp138283_c0_seq2,2702,40.8586,0.62493403,19,0,,2.00E-19,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,2.00E-16,ruditapes_c19418,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp138283_c0_seq4,940,41.7021,0.66179648,0,0,,7.00E-08,P15629,Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF02160;PF00078;,,,,,,,,,POL_SOCMV,Soybean chlorotic mottle virus, comp138283_c0_seq6,255,37.2549,0.46002504,4,0,,1.00E-08,P19199,Polyprotein P3 [Includes: Putative movement protein (MP); Capsid protein (Coat protein) (CP); Protease (PR) (EC 3.4.23.-); Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4)],Polyprotein P3 [Includes: Putative movement protein (MP); Capsid protein (Coat protein) (CP); Protease (PR) (EC 3.4.23.-); Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4)],GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0090305; GO:0006508; GO:0004523; GO:0046740; GO:0046718; GO:0075732; GO:0008270,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; spread of virus in host, cell to cell; viral entry into host cell; viral penetration into host nucleus; zinc ion binding",PF00077;PF00078;,,,,,,,,,POL_COYMV,Commelina yellow mottle virus (CoYMV),"transport of virus in host, cell to cell [GO:0046740]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]" comp138284_c0_seq2,1629,40.577,0.69725686,162,360,,5.00E-144,Q8K1J6,"CCA tRNA nucleotidyltransferase 1, mitochondrial (EC 2.7.7.72) (mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase)","CCA tRNA nucleotidyltransferase 1, mitochondrial (EC 2.7.7.72) (mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase)",GO:0005524; GO:0052929; GO:0052928; GO:0052927; GO:0005813; GO:0005739; GO:0042780; GO:0001680; GO:0004810; GO:0000049; GO:0009022,ATP binding; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity; CTP:3'-cytidine-tRNA cytidylyltransferase activity; CTP:tRNA cytidylyltransferase activity; centrosome; mitochondrion; tRNA 3'-end processing; tRNA 3'-terminal CCA addition; tRNA adenylyltransferase activity; tRNA binding; tRNA nucleotidyltransferase activity,PF01743;PF12627;,2.00E-59,CHOYP_TRNT1.1.1,,,,,,,TRNT1_MOUSE,Mus musculus (Mouse),tRNA 3'-end processing [GO:0042780]; tRNA 3'-terminal CCA addition [GO:0001680]; tRNA processing [GO:0008033] comp138286_c2_seq1,1589,34.9276,0.58345588,155,463,,4.00E-18,Q4VBD9,GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GO:0001658; GO:0005737; GO:0046872; GO:0000122; GO:0005730; GO:0005634; GO:0043565; GO:0006351,"branching involved in ureteric bud morphogenesis; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,GZF1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp138288_c1_seq1,1017,39.6264,0.75556728,70,147,,2.00E-22,Q03017,NF-kappa-B inhibitor cactus,NF-kappa-B inhibitor cactus,GO:0008063; GO:0019732; GO:0005737; GO:0042994; GO:0046843; GO:0009950; GO:0030097; GO:0045087; GO:0007399; GO:0031594; GO:0006909; GO:0006967; GO:0006974; GO:0008134,Toll signaling pathway; antifungal humoral response; cytoplasm; cytoplasmic sequestering of transcription factor; dorsal appendage formation; dorsal/ventral axis specification; hemopoiesis; innate immune response; nervous system development; neuromuscular junction; phagocytosis; positive regulation of antifungal peptide biosynthetic process; response to DNA damage stimulus; transcription factor binding,PF00023;PF12796;,,,1.00E-25,ruditapes_c16255,,,,,CACT_DROME,Drosophila melanogaster (Fruit fly),antifungal humoral response [GO:0019732]; antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic sequestering of transcription factor [GO:0042994]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal appendage formation [GO:0046843]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of protein import into nucleus [GO:0042308]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of antifungal peptide biosynthetic process [GO:0006967]; response to fungus [GO:0009620]; Toll signaling pathway [GO:0008063] comp138288_c1_seq2,1254,36.1244,0.48994761,86,209,,9.00E-08,Q29RV0,Cyclin-dependent kinase 4 inhibitor D (p19-INK4d),Cyclin-dependent kinase 4 inhibitor D (p19-INK4d),GO:0000731; GO:0000082; GO:0048102; GO:0007050; GO:0004861; GO:0005737; GO:0030308; GO:0008285; GO:0043154; GO:1902230; GO:0005634; GO:0000079; GO:0009411; GO:0032526; GO:0033280; GO:0007605,DNA synthesis involved in DNA repair; G1/S transition of mitotic cell cycle; autophagic cell death; cell cycle arrest; cyclin-dependent protein serine/threonine kinase inhibitor activity; cytoplasm; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity; response to UV; response to retinoic acid; response to vitamin D; sensory perception of sound,PF12796;,,,,,,,,,CDN2D_BOVIN,Bos taurus (Bovine),autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605] comp138293_c0_seq1,2052,44.9318,0.45403908,1539,11309,,2.00E-33,Q8CGZ0,Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6),Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6),GO:0003723; GO:0006396; GO:0005783; GO:0008285; GO:0048471; GO:0051533; GO:0051209,RNA binding; RNA processing; endoplasmic reticulum; negative regulation of cell proliferation; perinuclear region of cytoplasm; positive regulation of NFAT protein import into nucleus; release of sequestered calcium ion into cytosol,PF04818;PF01585;PF01805;,1.00E-50,CHOYP_CHERP.1.1,3.00E-56,ruditapes_c13166,,,,,CHERP_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell proliferation [GO:0008285]; positive regulation of NFAT protein import into nucleus [GO:0051533]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] comp138294_c1_seq1,1139,42.7568,0.41467502,5,14,,1.00E-18,P97358,TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 68 kDa) (TAFI68) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B),TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 68 kDa) (TAFI68) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B),GO:0001164; GO:0001187; GO:0070860; GO:0000120; GO:0046872,RNA polymerase I CORE element sequence-specific DNA binding; RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity; RNA polymerase I core factor complex; RNA polymerase I transcription factor complex; metal ion binding,PF11781;,,,,,,,,,TAF1B_MOUSE,Mus musculus (Mouse),chromatin silencing at rDNA [GO:0000183]; RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript [GO:0001189]; transcription from RNA polymerase I promoter [GO:0006360]; transcription initiation from RNA polymerase I promoter [GO:0006361] comp138295_c3_seq1,202,43.0693,0.1072965,5,4,,,,,,,,,2.00E-11,CHOYP_LOC100892567.6.8,,,,,,,,, comp138295_c4_seq2,476,42.6471,0.37041515,15,9,,1.00E-08,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,9.00E-13,CHOYP_LOC100887947.1.2,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp138297_c0_seq1,1755,36.8661,0.43992229,3118,22632,,3.00E-134,Q7L2H7,Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1),Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity; translational initiation,PF01399;,6.00E-92,CHOYP_MABP1.1.2,,,,,,,EIF3M_HUMAN,Homo sapiens (Human),cytoplasmic translational initiation [GO:0002183]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp138299_c1_seq1,355,30.1408,0.25141442,46,28,,9.00E-07,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp138300_c1_seq2,3976,33.2998,0.37703832,21,17,,2.00E-36,Q9VXF1,Serine/threonine-protein phosphatase 2B catalytic subunit 3 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A3 subunit),Serine/threonine-protein phosphatase 2B catalytic subunit 3 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A3 subunit),GO:0033192; GO:0046872; GO:0051533; GO:0006470; GO:0030431,calmodulin-dependent protein phosphatase activity; metal ion binding; positive regulation of NFAT protein import into nucleus; protein dephosphorylation; sleep,PF00149;,3.00E-37,CHOYP_LOC100904034.1.1,,,,,,,PP2B3_DROME,Drosophila melanogaster (Fruit fly),positive regulation of NFAT protein import into nucleus [GO:0051533]; protein dephosphorylation [GO:0006470]; sleep [GO:0030431] comp138300_c1_seq4,4706,34.5729,0.38769106,123,56,,0,Q27889,Serine/threonine-protein phosphatase 2B catalytic subunit 2 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A2 subunit),Serine/threonine-protein phosphatase 2B catalytic subunit 2 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A2 subunit),GO:0005955; GO:0005516; GO:0033192; GO:0009790; GO:0007143; GO:0046872; GO:0006470; GO:0030431; GO:0035220,calcineurin complex; calmodulin binding; calmodulin-dependent protein phosphatase activity; embryo development; female meiosis; metal ion binding; protein dephosphorylation; sleep; wing disc development,PF00149;,0,CHOYP_CNA1.1.1,,,,,,,PP2B2_DROME,Drosophila melanogaster (Fruit fly),female meiotic division [GO:0007143]; meiotic nuclear division [GO:0007126]; protein dephosphorylation [GO:0006470]; regulation of embryonic development [GO:0045995]; sleep [GO:0030431]; wing disc development [GO:0035220] comp138300_c1_seq6,759,38.0764,0.43766272,2,11,,5.00E-21,Q9LEV0,Serine/threonine-protein phosphatase 7 inactive homolog,Serine/threonine-protein phosphatase 7 inactive homolog,GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF00149;,8.00E-168,CHOYP_CNA1.1.1,,,,,,,PPP7I_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138301_c0_seq1,661,43.7216,0.60851615,21,39,,6.00E-64,P53893,Ribosome assembly protein 1 (EC 3.6.5.-) (EF-2-like GTPase) (Elongation factor-like 1),Ribosome assembly protein 1 (EC 3.6.5.-) (EF-2-like GTPase) (Elongation factor-like 1),GO:0005525; GO:0003924; GO:0005737; GO:0042256,GTP binding; GTPase activity; cytoplasm; mature ribosome assembly,PF00679;PF14492;PF03144;,2.00E-98,CHOYP_EFTUD1.1.1,,,,,,,RIA1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),mature ribosome assembly [GO:0042256] comp138301_c0_seq2,1723,45.9083,0.49542188,119,356,,0,Q8C0D5,Elongation factor Tu GTP-binding domain-containing protein 1,Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A),GO:0005525; GO:0003924; GO:0042256; GO:0043022; GO:0003746,GTP binding; GTPase activity; mature ribosome assembly; ribosome binding; translation elongation factor activity,PF00679;PF14492;,,,2.00E-18,ruditapes_c31249,,,,,ETUD1_MOUSE,Mus musculus (Mouse),mature ribosome assembly [GO:0042256] comp138302_c0_seq1,1405,38.79,0.84244507,1807,7027,,2.00E-08,Q6NWC6,Cleavage and polyadenylation specificity factor subunit 6,Cleavage and polyadenylation specificity factor subunit 6,GO:0003729; GO:0005849; GO:0006378; GO:0000166,mRNA binding; mRNA cleavage factor complex; mRNA polyadenylation; nucleotide binding,PF00076;,,,,,,,,,CPSF6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA polyadenylation [GO:0006378] comp138302_c1_seq1,1514,52.576,0.36155202,1547,4726,,7.00E-35,Q6NVF9,Cleavage and polyadenylation specificity factor subunit 6,Cleavage and polyadenylation specificity factor subunit 6,GO:0003729; GO:0005849; GO:0006378; GO:0000166; GO:0042382; GO:0051262; GO:0030529,mRNA binding; mRNA cleavage factor complex; mRNA polyadenylation; nucleotide binding; paraspeckles; protein tetramerization; ribonucleoprotein complex,PF00076;,6.00E-40,CHOYP_LOC100116878.1.1,,,,,,,CPSF6_MOUSE,Mus musculus (Mouse),mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; protein tetramerization [GO:0051262] comp138304_c0_seq1,2013,35.8172,1.03835229,13368,905,,2.00E-54,P02594,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,3.00E-27,CHOYP_CALM.50.50,6.00E-90,ruditapes_c8072,,,,,CALM_ELEEL,Electrophorus electricus (Electric eel) (Gymnotus electricus), comp138305_c0_seq5,289,34.9481,0.22925176,14,112,,,,,,,,,,,7.00E-16,ruditapes2_c1163,,,,,,, comp138305_c1_seq1,693,29.7258,0.39623263,19,895,,,,,,,,,,,4.00E-11,ruditapes_c4549,,,,,,, comp138314_c1_seq1,1150,38.6087,0.80425059,585,6342,,1.00E-16,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp138318_c0_seq1,1425,39.4386,0.51363615,25,45,,3.00E-62,Q08641,tRNA(Thr) (cytosine(32)-N(3))-methyltransferase (EC 2.1.1.268) (Actin-binding protein of 140 kDa) (tRNA methyltransferase of 140 kDa),tRNA(Thr) (cytosine(32)-N(3))-methyltransferase (EC 2.1.1.268) (Actin-binding protein of 140 kDa) (tRNA methyltransferase of 140 kDa),GO:0030479; GO:0005884; GO:0051015; GO:0032432; GO:0051017; GO:0030674; GO:0052735,"actin cortical patch; actin filament; actin filament binding; actin filament bundle; actin filament bundle assembly; protein binding, bridging; tRNA (cytosine-3-)-methyltransferase activity",PF08242;,2.00E-71,CHOYP_LOC101075807.1.1,,,,,,,AB140_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin filament bundle assembly [GO:0051017]; tRNA methylation [GO:0030488] comp138318_c0_seq2,1438,39.4993,0.50817939,3,37,,1.00E-133,Q5M8E6,Methyltransferase-like protein 2 (EC 2.1.1.-),Methyltransferase-like protein 2 (EC 2.1.1.-),GO:0016427,tRNA (cytosine) methyltransferase activity,,,,1.00E-52,ruditapes_c20093,,,,,METL2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),tRNA methylation [GO:0030488] comp138319_c1_seq1,1715,43.2653,0.48921069,0,0,,,,,,,,,5.00E-93,CHOYP_FACR1.2.2,,,,,,,,, comp138319_c1_seq2,1689,43.3985,0.49457493,0,0,,1.00E-97,Q960W6,Putative fatty acyl-CoA reductase CG8306 (EC 1.2.1.n2),Putative fatty acyl-CoA reductase CG8306 (EC 1.2.1.n2),GO:0080019; GO:0016021; GO:0006629; GO:0050062; GO:0005777; GO:0010025,fatty-acyl-CoA reductase (alcohol-forming) activity; integral to membrane; lipid metabolic process; long-chain-fatty-acyl-CoA reductase activity; peroxisome; wax biosynthetic process,PF07993;PF03015;,1.00E-93,CHOYP_FACR1.2.2,,,,,,,FACR3_DROME,Drosophila melanogaster (Fruit fly),lipid metabolic process [GO:0006629]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025] comp138319_c1_seq3,1796,42.0935,0.50647198,0,0,,2.00E-168,Q922J9,Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2),Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2),GO:0008611; GO:0080019; GO:0046474; GO:0016021; GO:0035336; GO:0050062; GO:0005778; GO:0005777; GO:0010025,ether lipid biosynthetic process; fatty-acyl-CoA reductase (alcohol-forming) activity; glycerophospholipid biosynthetic process; integral to membrane; long-chain fatty-acyl-CoA metabolic process; long-chain-fatty-acyl-CoA reductase activity; peroxisomal membrane; peroxisome; wax biosynthetic process,PF07993;PF03015;,1.00E-11,CHOYP_RN45S.3.5,,,,,,,FACR1_MOUSE,Mus musculus (Mouse),ether lipid biosynthetic process [GO:0008611]; glycerophospholipid biosynthetic process [GO:0046474]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025] comp138319_c1_seq5,1822,41.9868,0.50099637,0,0,,1.00E-70,A1ZAI3,Putative fatty acyl-CoA reductase CG8303 (EC 1.2.1.n2),Putative fatty acyl-CoA reductase CG8303 (EC 1.2.1.n2),GO:0080019; GO:0016021; GO:0006629; GO:0050062; GO:0005777; GO:0010025,fatty-acyl-CoA reductase (alcohol-forming) activity; integral to membrane; lipid metabolic process; long-chain-fatty-acyl-CoA reductase activity; peroxisome; wax biosynthetic process,PF07993;PF03015;,,,,,,,,,FACR2_DROME,Drosophila melanogaster (Fruit fly),lipid metabolic process [GO:0006629]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025] comp138322_c0_seq1,2028,38.3629,0.60859871,199,495,,1.00E-161,P13221,"Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)","Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)",GO:0006103; GO:0004069; GO:0047801; GO:0080130; GO:0006532; GO:0006533; GO:0006531; GO:0043679; GO:0031406; GO:0032869; GO:0005829; GO:0055089; GO:0019551; GO:0019550; GO:0006536; GO:0006114; GO:0005764; GO:0006107; GO:0004609; GO:0030170; GO:0051384,2-oxoglutarate metabolic process; L-aspartate:2-oxoglutarate aminotransferase activity; L-cysteine:2-oxoglutarate aminotransferase activity; L-phenylalanine:2-oxoglutarate aminotransferase activity; aspartate biosynthetic process; aspartate catabolic process; aspartate metabolic process; axon terminus; carboxylic acid binding; cellular response to insulin stimulus; cytosol; fatty acid homeostasis; glutamate catabolic process to 2-oxoglutarate; glutamate catabolic process to aspartate; glutamate metabolic process; glycerol biosynthetic process; lysosome; oxaloacetate metabolic process; phosphatidylserine decarboxylase activity; pyridoxal phosphate binding; response to glucocorticoid stimulus,PF00155;,4.00E-56,CHOYP_BRAFLDRAFT_124686.1.1,4.00E-23,ruditapes_c22318,,,,,AATC_RAT,Rattus norvegicus (Rat),2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular response to insulin stimulus [GO:0032869]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid homeostasis [GO:0055089]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; response to glucocorticoid [GO:0051384] comp138324_c1_seq1,437,43.0206,0.96019887,22,15,,2.00E-60,P48741,Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B),Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B),GO:0005524; GO:0006986,ATP binding; response to unfolded protein,PF00012;,2.00E-53,CHOYP_BRAFLDRAFT_114843.1.2,,,,,,,HSP77_HUMAN,Homo sapiens (Human), comp138324_c1_seq2,1398,42.0601,1.15348675,14,12,,4.00E-151,A5A8V7,Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L),Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,7.00E-115,CHOYP_HSP70.1.1,,,,,,,HS71L_PIG,Sus scrofa (Pig), comp138324_c1_seq3,1063,43.0856,1.11850252,3,0,,4.00E-84,P16121,Heat shock 70 kDa protein (Fragment),Heat shock 70 kDa protein (Fragment),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,,,3.00E-14,ruditapes2_c147,,,,,HSP70_LUPPO,Lupinus polyphyllus (Large-leaved lupin), comp138325_c1_seq2,1298,42.681,0.39163457,126,256,,2.00E-78,Q5RJY2,G2/M phase-specific E3 ubiquitin-protein ligase (EC 6.3.2.-),G2/M phase-specific E3 ubiquitin-protein ligase (EC 6.3.2.-),GO:0006915; GO:0001824; GO:0005737; GO:2001243; GO:0005730; GO:0000209; GO:0004842; GO:0008270,apoptotic process; blastocyst development; cytoplasm; negative regulation of intrinsic apoptotic signaling pathway; nucleolus; protein polyubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00632;,1.00E-42,CHOYP_BRAFLDRAFT_247017.1.1,,,,,,,G2E3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; protein polyubiquitination [GO:0000209] comp138328_c0_seq1,4184,43.738,0.97230478,3453,62,,4.00E-36,A5PLK6,Regulator of G-protein signaling protein-like,Regulator of G-protein signaling protein-like,GO:0016021; GO:0038032,integral to membrane; termination of G-protein coupled receptor signaling pathway,PF00615;,,,,,,,,,RGSL_HUMAN,Homo sapiens (Human), comp138330_c0_seq2,1304,40.1074,0.86309575,285,312,,2.00E-88,Q66I75,Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog),Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog),GO:0019284; GO:0019509; GO:0006915; GO:0005737; GO:0046570; GO:0008270,L-methionine biosynthetic process from S-adenosylmethionine; L-methionine salvage from methylthioadenosine; apoptotic process; cytoplasm; methylthioribulose 1-phosphate dehydratase activity; zinc ion binding,PF00596;,,,6.00E-37,ruditapes2_c67,,,,,MTNB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp138331_c0_seq1,1378,42.3077,0.29216117,228,1570,,4.00E-152,Q8BJM5,Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6),Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6),GO:0005794; GO:0006895; GO:0016021; GO:0005739; GO:0005385,Golgi apparatus; Golgi to endosome transport; integral to membrane; mitochondrion; zinc ion transmembrane transporter activity,PF01545;,4.00E-99,CHOYP_ZNT6A.1.1,,,,,,,ZNT6_MOUSE,Mus musculus (Mouse),Golgi to endosome transport [GO:0006895]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829] comp138336_c0_seq2,798,30.4511,0.27073775,53,114,,2.00E-15,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,1.00E-40,CHOYP_LOC100892567.8.8,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138339_c1_seq1,2100,28.8571,0.13745655,7,71,,1.00E-13,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp138339_c1_seq2,2087,28.7015,0.13980586,5,51,,8.00E-24,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp138339_c1_seq3,1000,35,0.32702833,14,17,,1.00E-07,Q9C5D2,F-box/LRR-repeat protein 4 (AtFBL4),F-box/LRR-repeat protein 4 (AtFBL4),,,PF12937;PF13516;,,,,,,,,,FBL4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138340_c0_seq1,1566,36.8455,0.58170787,5,17,,8.00E-92,Q8BK64,Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1),Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1),GO:0001671; GO:0005737; GO:0005829; GO:0005783; GO:0006457; GO:0006950,ATPase activator activity; cytoplasm; cytosol; endoplasmic reticulum; protein folding; response to stress,PF09229;PF08327;,,,,,,,,,AHSA1_MOUSE,Mus musculus (Mouse),protein folding [GO:0006457]; response to stress [GO:0006950] comp138340_c0_seq2,1423,36.9642,0.52838616,4,0,,1.00E-20,Q55DB6,Activator of 90 kDa heat shock protein ATPase homolog,Activator of 90 kDa heat shock protein ATPase homolog,GO:0001671; GO:0005737; GO:0032781; GO:0006950,ATPase activator activity; cytoplasm; positive regulation of ATPase activity; response to stress,PF09229;PF08327;,4.00E-68,CHOYP_LOC100368486.1.1,,,,,,,AHSA_DICDI,Dictyostelium discoideum (Slime mold),response to stress [GO:0006950] comp138342_c0_seq1,1757,39.1007,0.70355949,8,79,,3.00E-42,Q9LEW8,"Protein-ribulosamine 3-kinase, chloroplastic (EC 2.7.1.172) (Fructosamine 3-kinase-related protein) (AtFN3K-RP)","Protein-ribulosamine 3-kinase, chloroplastic (EC 2.7.1.172) (Fructosamine 3-kinase-related protein) (AtFN3K-RP)",GO:0009507; GO:0016301; GO:0005739,chloroplast; kinase activity; mitochondrion,PF03881;,5.00E-29,CHOYP_FN3K.1.1,,,,,,,FN3KR_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138342_c0_seq2,2117,39.3009,0.76155697,111,274,,4.00E-83,Q9HA64,Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein),Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein),GO:0016301,kinase activity,PF03881;,,,,,,,,,KT3K_HUMAN,Homo sapiens (Human),post-translational protein modification [GO:0043687] comp138342_c0_seq3,930,37.957,0.66400907,14,70,,3.00E-14,P46382,Uncharacterized protein in tonB 3'region (Fragment),Uncharacterized protein in tonB 3'region (Fragment),GO:0016301,kinase activity,PF03881;,,,,,,,,,YNIA_KLEPN,Klebsiella pneumoniae, comp138345_c0_seq4,384,39.5833,0.53780703,61,247,,1.00E-06,Q9D8X0,Protein MANBAL,Protein MANBAL,GO:0016021,integral to membrane,PF06783;,,,1.00E-14,ruditapes_c10081,,,,,MANBL_MOUSE,Mus musculus (Mouse), comp138346_c0_seq1,1356,43.5103,0.25305375,79,1467,,8.00E-137,Q99L13,"3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)","3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)",GO:0008442; GO:0051287; GO:0005739; GO:0006098; GO:0004616; GO:0006574,3-hydroxyisobutyrate dehydrogenase activity; NAD binding; mitochondrion; pentose-phosphate shunt; phosphogluconate dehydrogenase (decarboxylating) activity; valine catabolic process,PF14833;PF03446;,1.00E-68,CHOYP_BRAFLDRAFT_270300.1.1,,,,,,,3HIDH_MOUSE,Mus musculus (Mouse),valine catabolic process [GO:0006574] comp138348_c0_seq1,1159,41.5876,0.52404821,487,1837,,9.00E-98,Q7ZWY2,PIH1 domain-containing protein 1,PIH1 domain-containing protein 1,,,PF08190;,1.00E-53,CHOYP_BRAFLDRAFT_287356.1.1,3.00E-59,ruditapes2_c2428,,,,,PIHD1_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138350_c0_seq2,2920,42.6712,0.54253769,7,2,,7.00E-63,Q5ZLD2,DEP domain-containing protein 1B,DEP domain-containing protein 1B,GO:0005096; GO:0005622; GO:0035556; GO:0043547,GTPase activator activity; intracellular; intracellular signal transduction; positive regulation of GTPase activity,PF00610;PF00620;,7.00E-43,CHOYP_EP15R.1.1,,,,,,,DEP1B_CHICK,Gallus gallus (Chicken),intracellular signal transduction [GO:0035556] comp138350_c0_seq3,1989,41.9306,0.54947092,0,5,,,,,,,,,,,9.00E-82,ruditapes_c15700,,,,,,, comp138350_c0_seq4,2764,43.1983,0.52846678,0,30,,1.00E-61,Q8BH88,DEP domain-containing protein 1B,DEP domain-containing protein 1B,GO:0005096; GO:0005622; GO:0035556; GO:0043547,GTPase activator activity; intracellular; intracellular signal transduction; positive regulation of GTPase activity,PF00610;PF00620;,1.00E-40,CHOYP_EP15R.1.1,,,,,,,DEP1B_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; positive regulation of Wnt signaling pathway [GO:0030177] comp138354_c0_seq1,1619,36.0099,0.34894588,4,11,,9.00E-50,Q9BZ01,Protein FRG1B,,,,,9.00E-26,CHOYP_LOC100123667.1.1,2.00E-43,ruditapes_c28093,,,,,FRG1B_HUMAN,, comp138354_c0_seq3,1917,36.6197,0.36518222,21,50,,7.00E-69,O73747,Protein FRG1,Protein FRG1,GO:0015030; GO:0016607; GO:0006364,Cajal body; nuclear speck; rRNA processing,PF06229;,,,,,,,,,FRG1_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),muscle organ development [GO:0007517]; rRNA processing [GO:0006364] comp138354_c0_seq4,1760,35.9091,0.37700334,12,14,,1.00E-68,O73747,Protein FRG1,Protein FRG1,GO:0015030; GO:0016607; GO:0006364,Cajal body; nuclear speck; rRNA processing,PF06229;,,,,,,,,,FRG1_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),muscle organ development [GO:0007517]; rRNA processing [GO:0006364] comp138358_c3_seq1,1672,42.2249,0.54148986,0,0,,1.00E-117,Q21734,Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1),Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1),GO:0005524; GO:0007243; GO:0000287; GO:0004674,ATP binding; intracellular protein kinase cascade; magnesium ion binding; protein serine/threonine kinase activity,PF00069;PF00433;,5.00E-35,CHOYP_KS6A1.1.1,,,,,,,KS6A1_CAEEL,Caenorhabditis elegans,intracellular signal transduction [GO:0035556] comp138358_c3_seq10,1567,41.2253,0.4900337,0,0,,0,Q8BSK8,Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA),Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA),GO:0005524; GO:0000082; GO:0031929; GO:0007568; GO:0006915; GO:0030054; GO:0016477; GO:0009986; GO:0071363; GO:0032870; GO:0007281; GO:0007616; GO:0005741; GO:0005739; GO:0043066; GO:2001237; GO:0046627; GO:0043005; GO:0005634; GO:0042277; GO:0048471; GO:0045931; GO:0048633; GO:0014911; GO:0048661; GO:0045948; GO:0043491; GO:0004672; GO:0046324; GO:0042493; GO:0014878; GO:0045471; GO:0033762; GO:0051384; GO:0009749; GO:0009408; GO:0032868; GO:0043201; GO:0032496; GO:0009612; GO:0007584; GO:0033574; GO:0009636; GO:0034612; GO:0009611; GO:0004711; GO:0014732; GO:0003009; GO:0045202,ATP binding; G1/S transition of mitotic cell cycle; TOR signaling cascade; aging; apoptotic process; cell junction; cell migration; cell surface; cellular response to growth factor stimulus; cellular response to hormone stimulus; germ cell development; long-term memory; mitochondrial outer membrane; mitochondrion; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of insulin receptor signaling pathway; neuron projection; nucleus; peptide binding; perinuclear region of cytoplasm; positive regulation of mitotic cell cycle; positive regulation of skeletal muscle tissue growth; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of translational initiation; protein kinase B signaling cascade; protein kinase activity; regulation of glucose import; response to drug; response to electrical stimulus involved in regulation of muscle adaptation; response to ethanol; response to glucagon stimulus; response to glucocorticoid stimulus; response to glucose stimulus; response to heat; response to insulin stimulus; response to leucine; response to lipopolysaccharide; response to mechanical stimulus; response to nutrient; response to testosterone stimulus; response to toxic substance; response to tumor necrosis factor; response to wounding; ribosomal protein S6 kinase activity; skeletal muscle atrophy; skeletal muscle contraction; synapse,PF00069;PF00433;,,,,,,,,,KS6B1_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-term memory [GO:0007616]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to drug [GO:0042493]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929] comp138358_c3_seq11,1040,41.0577,0.40200392,0,0,,1.00E-59,O43930,Putative serine/threonine-protein kinase PRKY (EC 2.7.11.1),Putative serine/threonine-protein kinase PRKY (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,8.00E-18,CHOYP_LOC100367908.2.2,,,,,,,PRKY_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468] comp138358_c3_seq2,1537,42.8107,0.51772428,2,0,,0,Q8BSK8,Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA),Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA),GO:0005524; GO:0000082; GO:0031929; GO:0007568; GO:0006915; GO:0030054; GO:0016477; GO:0009986; GO:0071363; GO:0032870; GO:0007281; GO:0007616; GO:0005741; GO:0005739; GO:0043066; GO:2001237; GO:0046627; GO:0043005; GO:0005634; GO:0042277; GO:0048471; GO:0045931; GO:0048633; GO:0014911; GO:0048661; GO:0045948; GO:0043491; GO:0004672; GO:0046324; GO:0042493; GO:0014878; GO:0045471; GO:0033762; GO:0051384; GO:0009749; GO:0009408; GO:0032868; GO:0043201; GO:0032496; GO:0009612; GO:0007584; GO:0033574; GO:0009636; GO:0034612; GO:0009611; GO:0004711; GO:0014732; GO:0003009; GO:0045202,ATP binding; G1/S transition of mitotic cell cycle; TOR signaling cascade; aging; apoptotic process; cell junction; cell migration; cell surface; cellular response to growth factor stimulus; cellular response to hormone stimulus; germ cell development; long-term memory; mitochondrial outer membrane; mitochondrion; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of insulin receptor signaling pathway; neuron projection; nucleus; peptide binding; perinuclear region of cytoplasm; positive regulation of mitotic cell cycle; positive regulation of skeletal muscle tissue growth; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of translational initiation; protein kinase B signaling cascade; protein kinase activity; regulation of glucose import; response to drug; response to electrical stimulus involved in regulation of muscle adaptation; response to ethanol; response to glucagon stimulus; response to glucocorticoid stimulus; response to glucose stimulus; response to heat; response to insulin stimulus; response to leucine; response to lipopolysaccharide; response to mechanical stimulus; response to nutrient; response to testosterone stimulus; response to toxic substance; response to tumor necrosis factor; response to wounding; ribosomal protein S6 kinase activity; skeletal muscle atrophy; skeletal muscle contraction; synapse,PF00069;PF00433;,0,CHOYP_KS6B1.1.1,,,,,,,KS6B1_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-term memory [GO:0007616]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to drug [GO:0042493]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929] comp138360_c0_seq1,3101,42.5669,0.97107448,9,32,,1.00E-41,Q7XBS0,Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3),Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3),GO:0016021; GO:0005886; GO:0015293; GO:0015204,integral to membrane; plasma membrane; symporter activity; urea transmembrane transporter activity,PF00474;,,,,,,,,,DUR3_ORYSJ,Oryza sativa subsp. japonica (Rice),urea transmembrane transport [GO:0071918] comp138360_c0_seq2,3116,42.5546,0.97433126,18,37,,1.00E-41,Q7XBS0,Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3),Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3),GO:0016021; GO:0005886; GO:0015293; GO:0015204,integral to membrane; plasma membrane; symporter activity; urea transmembrane transporter activity,PF00474;,,,,,,,,,DUR3_ORYSJ,Oryza sativa subsp. japonica (Rice),urea transmembrane transport [GO:0071918] comp138361_c0_seq1,2575,32.5437,0.6219326,24,61,,7.00E-14,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp138361_c0_seq3,2586,32.5986,0.6164557,35,8,,1.00E-15,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138361_c0_seq5,1873,33.4757,0.61950431,20,7,,7.00E-23,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138361_c0_seq9,1896,33.9662,0.6674683,14,1,,5.00E-11,Q03278,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO21_NASVI,Nasonia vitripennis (Parasitic wasp), comp138362_c0_seq1,1946,43.9363,0.45986917,8,2,,7.00E-61,Q6ZRS2,Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator),Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator),GO:0005524; GO:0003677; GO:0005794; GO:0004386; GO:0004402; GO:0019048; GO:0005634; GO:0043234; GO:0006357; GO:0003713; GO:0006351,"ATP binding; DNA binding; Golgi apparatus; helicase activity; histone acetyltransferase activity; modulation by virus of host morphology or physiology; nucleus; protein complex; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription, DNA-dependent",PF00271;PF07529;PF00176;,,,,,,,,,SRCAP_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp138362_c0_seq2,2428,44.5222,0.46234971,377,335,,2.00E-59,Q9NDJ2,Helicase domino (EC 3.6.4.-),Helicase domino (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0008094; GO:0035267; GO:0007049; GO:0070983; GO:0016458; GO:0004386; GO:0030097; GO:0016573; GO:0043486; GO:0002165; GO:0035207; GO:0048477; GO:0045747; GO:2000637; GO:0000381; GO:0006355; GO:0006351; GO:0035222,"ATP binding; DNA binding; DNA-dependent ATPase activity; NuA4 histone acetyltransferase complex; cell cycle; dendrite guidance; gene silencing; helicase activity; hemopoiesis; histone acetylation; histone exchange; instar larval or pupal development; negative regulation of hemocyte proliferation; oogenesis; positive regulation of Notch signaling pathway; positive regulation of gene silencing by miRNA; regulation of alternative mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; transcription, DNA-dependent; wing disc pattern formation",PF00271;PF07529;PF00176;,2.00E-80,CHOYP_LOC100115939.1.1,,,,,,,DOM_DROME,Drosophila melanogaster (Fruit fly),"cell cycle [GO:0007049]; cell proliferation [GO:0008283]; chromatin organization [GO:0006325]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; gene silencing [GO:0016458]; hemopoiesis [GO:0030097]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; instar larval or pupal development [GO:0002165]; male germ-line stem cell population maintenance [GO:0036098]; negative regulation of gene expression [GO:0010629]; negative regulation of hemocyte proliferation [GO:0035207]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; sensory perception of pain [GO:0019233]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]" comp138363_c0_seq2,2052,43.3236,0.5716985,0,0,,0,Q9ULM6,CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase),CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase),GO:0030014; GO:0003723; GO:0005829; GO:0043928; GO:0035195; GO:0046872; GO:0070966; GO:0000289; GO:0005634; GO:0004535; GO:0008284; GO:0010606; GO:2000327; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; RNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene silencing by miRNA; metal ion binding; nuclear-transcribed mRNA catabolic process, no-go decay; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; poly(A)-specific ribonuclease activity; positive regulation of cell proliferation; positive regulation of cytoplasmic mRNA processing body assembly; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF03372;PF13855;,2.00E-131,CHOYP_LOC100122037.1.1,,,,,,,CNOT6_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138363_c0_seq5,1835,43.5967,0.4934529,0,0,,5.00E-72,Q6CEJ6,Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0005634; GO:0004535; GO:0006355; GO:0006351,"RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus; poly(A)-specific ribonuclease activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03372;,7.00E-123,CHOYP_LOC100869625.1.1,,,,,,,CCR4_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138363_c0_seq6,969,45.7172,0.59363588,0,0,,3.00E-150,Q9ULM6,CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase),CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase),GO:0030014; GO:0003723; GO:0005829; GO:0043928; GO:0035195; GO:0046872; GO:0070966; GO:0000289; GO:0005634; GO:0004535; GO:0008284; GO:0010606; GO:2000327; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; RNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene silencing by miRNA; metal ion binding; nuclear-transcribed mRNA catabolic process, no-go decay; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; poly(A)-specific ribonuclease activity; positive regulation of cell proliferation; positive regulation of cytoplasmic mRNA processing body assembly; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF03372;PF13855;,,,,,,,,,CNOT6_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138364_c2_seq2,1524,42.126,1.08867899,269,430,,5.00E-09,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp138365_c0_seq1,3371,38.9795,0.33771446,249,902,,1.00E-13,Q6P9P0,Protein FAM178A,SMC5-SMC6 complex localization factor protein 2,,,PF14816;,,,,,,,,,F178A_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166] comp138367_c0_seq1,1511,38.1205,0.50138189,1687,8901,,0,O35593,26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (MAD1),26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (MAD1),GO:0000724; GO:0006303; GO:0061133; GO:0004175; GO:0046872; GO:0008237; GO:0008541; GO:0070536; GO:0006508; GO:0061136; GO:0004221,"double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end joining; endopeptidase activator activity; endopeptidase activity; metal ion binding; metallopeptidase activity; proteasome regulatory particle, lid subcomplex; protein K63-linked deubiquitination; proteolysis; regulation of proteasomal protein catabolic process; ubiquitin thiolesterase activity",PF01398;PF13012;,0,CHOYP_PSDE.1.1,3.00E-111,ruditapes_c7775,,,,,PSDE_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; protein K63-linked deubiquitination [GO:0070536]; regulation of proteasomal protein catabolic process [GO:0061136]; response to ethanol [GO:0045471] comp138368_c0_seq1,1819,41.8362,0.60633842,213,960,,0,Q9DC48,Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (PRP17 homolog),Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (PRP17 homolog),GO:0008380; GO:0071013; GO:0006397,RNA splicing; catalytic step 2 spliceosome; mRNA processing,PF00400;,0,CHOYP_LOC100883571.1.1,,,,,,,PRP17_MOUSE,Mus musculus (Mouse),generation of catalytic spliceosome for second transesterification step [GO:0000350] comp138370_c1_seq1,880,33.4091,0.5457975,9,165,,1.00E-19,Q9H299,SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1) (SH3BP-1),SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1) (SH3BP-1),GO:0045454; GO:0005737; GO:0009055; GO:0005634; GO:0015035,cell redox homeostasis; cytoplasm; electron carrier activity; nucleus; protein disulfide oxidoreductase activity,PF04908;,,,,,,,,,SH3L3_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; positive regulation of GTPase activity [GO:0043547]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament depolymerization [GO:0030834]; regulation of blood vessel endothelial cell migration [GO:0043535] comp138373_c1_seq3,234,44.8718,0.27389778,3,27,,2.00E-06,P81015,Granulin-3,Granulin-3,GO:0005615,extracellular space,PF00396;,,,,,,,,,GRN3_CYPCA,Cyprinus carpio (Common carp), comp138373_c1_seq6,228,46.4912,0.17186072,138,161,,7.00E-06,P81014,Granulin-2,Granulin-2,GO:0005615,extracellular space,PF00396;,1.00E-25,CHOYP_LOC100366380.4.4,,,,,,,GRN2_CYPCA,Cyprinus carpio (Common carp), comp138373_c1_seq7,921,41.4767,0.41460379,61,429,,9.00E-26,P28799,Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)],Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)],GO:0001835; GO:0008219; GO:0007566; GO:0005615; GO:0008083; GO:0043231; GO:0005739; GO:0050679; GO:0007165,blastocyst hatching; cell death; embryo implantation; extracellular space; growth factor activity; intracellular membrane-bounded organelle; mitochondrion; positive regulation of epithelial cell proliferation; signal transduction,PF00396;,,,,,,,,,GRN_HUMAN,Homo sapiens (Human),chondrocyte proliferation [GO:0035988]; male mating behavior [GO:0060179]; neural precursor cell proliferation [GO:0061351]; positive regulation of dendritic spine development [GO:0060999]; response to estradiol [GO:0032355]; signal transduction [GO:0007165]; synaptic vesicle endocytosis [GO:0048488] comp138375_c2_seq3,818,34.3521,0.45638366,6,24,,,,,,,,,,,3.00E-13,ruditapes_c16991,,,,,,, comp138383_c0_seq1,2242,38.4924,0.4002499,324,58,,2.00E-93,Q54PP1,Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase),Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase),GO:0050613; GO:0005789; GO:0006696; GO:0016021,delta14-sterol reductase activity; endoplasmic reticulum membrane; ergosterol biosynthetic process; integral to membrane,PF01222;,1.00E-70,CHOYP_LOC581447.1.1,,,,,,,ERG24_DICDI,Dictyostelium discoideum (Slime mold),sterol biosynthetic process [GO:0016126] comp138383_c0_seq2,2209,38.7958,0.41190216,151,71,,6.00E-152,P23913,Lamin-B receptor,Lamin-B receptor,GO:0003677; GO:0016021; GO:0005637; GO:0016628,"DNA binding; integral to membrane; nuclear inner membrane; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor",PF01222;PF09465;,1.00E-70,CHOYP_LOC581447.1.1,,,,,,,LBR_CHICK,Gallus gallus (Chicken),sterol biosynthetic process [GO:0016126] comp138384_c0_seq1,3024,37.9299,0.89609726,0,7,,9.00E-11,P02542,Desmin,Desmin,GO:0005737; GO:0005882; GO:0005198,cytoplasm; intermediate filament; structural molecule activity,PF00038;PF04732;,,,,,,,,,DESM_CHICK,Gallus gallus (Chicken),intermediate filament organization [GO:0045109] comp138384_c0_seq2,3042,38.1986,0.91674309,43,134,,2.00E-30,P16275,Non-neuronal cytoplasmic intermediate filament protein B (IFB),Non-neuronal cytoplasmic intermediate filament protein B (IFB),GO:0005737; GO:0005882; GO:0005198,cytoplasm; intermediate filament; structural molecule activity,PF00038;,,,,,,,,,IFEB_HELPO,Helix pomatia (Roman snail) (Edible snail), comp138384_c0_seq3,3162,39.4687,0.98090267,24,40,,7.00E-30,P16275,Non-neuronal cytoplasmic intermediate filament protein B (IFB),Non-neuronal cytoplasmic intermediate filament protein B (IFB),GO:0005737; GO:0005882; GO:0005198,cytoplasm; intermediate filament; structural molecule activity,PF00038;,,,,,,,,,IFEB_HELPO,Helix pomatia (Roman snail) (Edible snail), comp138384_c0_seq4,3144,39.1539,0.97616568,0,0,,2.00E-28,P90901,Intermediate filament protein ifa-1 (Cel IF A1) (Intermediate filament protein A1) (IF-A1),Intermediate filament protein ifa-1 (Cel IF A1) (Intermediate filament protein A1) (IF-A1),GO:0005737; GO:0005882; GO:0005198,cytoplasm; intermediate filament; structural molecule activity,PF00038;PF00932;,,,,,,,,,IFA1_CAEEL,Caenorhabditis elegans, comp138387_c0_seq1,1744,45.2982,0.79425498,42277,44959,,0,P11833,Tubulin beta chain (Beta-tubulin),Tubulin beta chain (Beta-tubulin),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC373275.3.7,0,ruditapes2_c4168,,,,,TBB_PARLI,Paracentrotus lividus (Common sea urchin),microtubule-based process [GO:0007017] comp138387_c0_seq2,1731,45.9272,0.81126203,6596,13900,,0,Q9NFZ7,Tubulin beta-1 chain (Beta-tubulin 1),Tubulin beta-1 chain (Beta-tubulin 1),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC100367715.1.1,0,ruditapes_c2743,,,,,TBB1_ECHMU,Echinococcus multilocularis (Fox tapeworm),microtubule-based process [GO:0007017] comp138387_c0_seq3,767,48.3703,0.76128409,5680,10154,,9.00E-159,P11833,Tubulin beta chain (Beta-tubulin),Tubulin beta chain (Beta-tubulin),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,2.00E-12,CHOYP_TBB4B.6.7,,,,,,,TBB_PARLI,Paracentrotus lividus (Common sea urchin),microtubule-based process [GO:0007017] comp138390_c0_seq1,1548,41.7959,0.38743643,119,550,,7.00E-167,Q3UMM4,Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10),Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10),GO:0005524; GO:0004693,ATP binding; cyclin-dependent protein serine/threonine kinase activity,PF00069;,1.00E-118,CHOYP_CDK10.1.1,,,,,,,CDK10_MOUSE,Mus musculus (Mouse),positive regulation of MAPK cascade [GO:0043410] comp138392_c1_seq2,430,26.0465,0.58106145,0,19,,,,,,,,,,,1.00E-14,ruditapes_c9745,,,,,,, comp138393_c0_seq1,2059,35.5512,0.48271079,134,232,,1.00E-36,Q0VCS9,Ankyrin repeat and MYND domain-containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,GO:0005929; GO:0046872,cilium; metal ion binding,PF12796;PF01753;,,,,,,,,,ANKY2_BOVIN,Bos taurus (Bovine), comp138397_c0_seq1,1121,34.3443,0.58476018,347,939,,3.00E-06,Q6R7K3,Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1),Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1),GO:0006260; GO:0009186; GO:0046872; GO:0004748,"DNA replication; deoxyribonucleoside diphosphate metabolic process; metal ion binding; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",PF02661;PF00268;,,,,,,,,,RIR2_OSHVF,Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus),deoxyribonucleoside diphosphate metabolic process [GO:0009186]; DNA replication [GO:0006260] comp138398_c0_seq1,437,39.1304,0.99123574,6,27,,6.00E-13,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp138403_c1_seq1,2087,42.3095,0.7183413,107,597,,3.00E-114,P31646,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0042165; GO:0006836; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter binding; neurotransmitter transport; neurotransmitter:sodium symporter activity,PF00209;,2.00E-15,CHOYP_LOC100368611.1.1,,,,,,,S6A13_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836] comp138405_c2_seq4,986,33.8742,0.21296052,107,329,,,,,,,,,,,4.00E-12,ruditapes_c8275,,,,,,, comp138406_c0_seq1,1529,37.6717,0.9599425,147,925,,2.00E-08,Q5UBV8,Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor),Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor),GO:0007250; GO:0006919; GO:0042107; GO:0005615; GO:0006955; GO:0016021; GO:0005886,activation of NF-kappaB-inducing kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; cytokine metabolic process; extracellular space; immune response; integral to membrane; plasma membrane,PF00229;,,,,,,,,,TNF15_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955] comp138407_c0_seq3,1251,38.4492,0.51950241,15,39,,7.00E-79,P82251,"B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)","b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)",GO:0015184; GO:0007596; GO:0006520; GO:0005887; GO:0050900; GO:0015175; GO:0042605; GO:0006461,L-cystine transmembrane transporter activity; blood coagulation; cellular amino acid metabolic process; integral to plasma membrane; leukocyte migration; neutral amino acid transmembrane transporter activity; peptide antigen binding; protein complex assembly,PF13520;,1.00E-60,CHOYP_LOC100378220.1.1,,,,,,,BAT1_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; leukocyte migration [GO:0050900]; neutral amino acid transport [GO:0015804]; protein complex assembly [GO:0006461] comp138407_c1_seq1,404,44.5545,0.86538992,0,0,,3.00E-09,P41216,Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1),Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1),GO:0005524; GO:0033211; GO:0005789; GO:0016021; GO:0008610; GO:0044539; GO:0004467; GO:0005741; GO:0005739; GO:0005778; GO:0005886; GO:0071902; GO:0042493; GO:0007584; GO:0034201; GO:0014070; GO:0006641; GO:0042178,ATP binding; adiponectin-mediated signaling pathway; endoplasmic reticulum membrane; integral to membrane; lipid biosynthetic process; long-chain fatty acid import; long-chain fatty acid-CoA ligase activity; mitochondrial outer membrane; mitochondrion; peroxisomal membrane; plasma membrane; positive regulation of protein serine/threonine kinase activity; response to drug; response to nutrient; response to oleic acid; response to organic cyclic compound; triglyceride metabolic process; xenobiotic catabolic process,PF00501;,,,,,,,,,ACSL1_MOUSE,Mus musculus (Mouse),adiponectin-activated signaling pathway [GO:0033211]; lipid biosynthetic process [GO:0008610]; long-chain fatty acid import [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; response to oleic acid [GO:0034201]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641]; xenobiotic catabolic process [GO:0042178] comp138407_c1_seq2,514,44.1634,0.89849666,0,7,,2.00E-16,Q9M0X9,4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6),4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6),GO:0005524; GO:0004321; GO:0009695; GO:0016874; GO:0031408; GO:0005777,ATP binding; fatty-acyl-CoA synthase activity; jasmonic acid biosynthetic process; ligase activity; oxylipin biosynthetic process; peroxisome,PF00501;PF13193;,,,,,,,,,4CLL7_ARATH,Arabidopsis thaliana (Mouse-ear cress),jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408] comp138411_c0_seq3,1315,46.1597,0.97290772,14,122,,3.00E-118,A0JMP0,Acid trehalase-like protein 1 (EC 3.2.1.-),Acid trehalase-like protein 1 (EC 3.2.1.-),GO:0005975; GO:0016798,"carbohydrate metabolic process; hydrolase activity, acting on glycosyl bonds",PF03632;,,,,,,,,,ATHL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate metabolic process [GO:0005975] comp138411_c0_seq5,969,47.0588,1.01090525,0,0,,2.00E-32,Q8RBL8,Kojibiose phosphorylase (EC 2.4.1.230),Kojibiose phosphorylase (EC 2.4.1.230),GO:0030246; GO:0005975; GO:0033831,carbohydrate binding; carbohydrate metabolic process; kojibiose phosphorylase activity,PF03633;PF03632;PF03636;,,,,,,,,,KOJP_THETN,Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis),carbohydrate metabolic process [GO:0005975] comp138413_c0_seq1,2915,44.3568,0.61055284,27,18,,8.00E-111,Q6GQQ9,OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne),OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne),GO:0003677; GO:0005737; GO:0015630; GO:0002385; GO:0043124; GO:0005634; GO:0035871; GO:0071108; GO:0070536; GO:0006508; GO:0004221; GO:0004843; GO:0008270,DNA binding; cytoplasm; microtubule cytoskeleton; mucosal immune response; negative regulation of I-kappaB kinase/NF-kappaB cascade; nucleus; protein K11-linked deubiquitination; protein K48-linked deubiquitination; protein K63-linked deubiquitination; proteolysis; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding,PF02338;PF01754;,,,,,,,,,OTU7B_HUMAN,Homo sapiens (Human),immune response [GO:0006955]; mucosal immune response [GO:0002385]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536] comp138413_c0_seq3,2481,44.8609,0.57393834,0,0,,2.00E-47,Q4R8W3,Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 3.4.19.12) (EC 6.3.2.-) [Cleaved into: A20p50; A20p37],Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 3.4.19.12) (EC 6.3.2.-) [Cleaved into: A20p50; A20p37],GO:0003677; GO:0006915; GO:0070301; GO:0006954; GO:0005764; GO:0043124; GO:0050728; GO:0045824; GO:0005634; GO:0035871; GO:0071108; GO:0070936; GO:0070536; GO:0006508; GO:0004221; GO:0004842; GO:0004843; GO:0008270,DNA binding; apoptotic process; cellular response to hydrogen peroxide; inflammatory response; lysosome; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of inflammatory response; negative regulation of innate immune response; nucleus; protein K11-linked deubiquitination; protein K48-linked deubiquitination; protein K48-linked ubiquitination; protein K63-linked deubiquitination; proteolysis; ubiquitin thiolesterase activity; ubiquitin-protein ligase activity; ubiquitin-specific protease activity; zinc ion binding,PF02338;PF01754;,1.00E-69,CHOYP_LOC581645.1.1,,,,,,,TNAP3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),apoptotic process [GO:0006915]; cellular response to hydrogen peroxide [GO:0070301]; inflammatory response [GO:0006954]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536] comp138414_c0_seq1,2543,38.6158,0.80112539,89490,286630,,1.00E-47,P41824,Y-box factor homolog (APY1),Y-box factor homolog (APY1),GO:0003677; GO:0003723; GO:0005634; GO:0006355; GO:0006351,"DNA binding; RNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00313;,3.00E-85,CHOYP_LOC100370246.2.2,2.00E-58,ruditapes_c24388,,,,,YBOXH_APLCA,Aplysia californica (California sea hare),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138415_c0_seq1,1838,43.1447,0.55284585,1,0,,0,Q7QG73,AP-2 complex subunit alpha (Alpha-adaptin),AP-2 complex subunit alpha (Alpha-adaptin),GO:0030131; GO:0005905; GO:0006886; GO:0005886; GO:0008565; GO:0048488,clathrin adaptor complex; coated pit; intracellular protein transport; plasma membrane; protein transporter activity; synaptic vesicle endocytosis,PF01602;PF02296;PF02883;,0,CHOYP_AP2A2.1.1,,,,,,,AP2A_ANOGA,Anopheles gambiae (African malaria mosquito),intracellular protein transport [GO:0006886]; protein transport [GO:0015031]; synaptic vesicle endocytosis [GO:0048488] comp138415_c0_seq2,1140,43.5088,0.501188,0,0,,6.00E-11,Q12028,AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin),AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin),GO:0030121; GO:0006896; GO:0030276; GO:0006886; GO:0008565,AP-1 adaptor complex; Golgi to vacuole transport; clathrin binding; intracellular protein transport; protein transporter activity,PF01602;PF02883;,1.00E-67,CHOYP_LOC100366818.1.1,,,,,,,AP1G1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp138416_c0_seq1,1405,40.3559,0.41985837,104,191,,7.00E-93,C3YFB4,Anamorsin homolog (Fe-S cluster assembly protein DRE2 homolog),Anamorsin homolog (Fe-S cluster assembly protein DRE2 homolog),GO:0051537; GO:0006915; GO:0009055; GO:0016226; GO:0046872; GO:0005758; GO:0043066,"2 iron, 2 sulfur cluster binding; apoptotic process; electron carrier activity; iron-sulfur cluster assembly; metal ion binding; mitochondrial intermembrane space; negative regulation of apoptotic process",PF05093;,2.00E-32,CHOYP_DRE2.2.2,,,,,,,DRE2_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),apoptotic process [GO:0006915]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of apoptotic process [GO:0043066] comp138417_c0_seq1,877,40.821,0.32883938,7,191,,3.00E-76,Q9D3B1,Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B),Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B),GO:0005789; GO:0006633; GO:0016021; GO:0016829,endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; lyase activity,PF04387;,,,,,,,,,HACD2_MOUSE,Mus musculus (Mouse),fatty acid elongation [GO:0030497]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] comp138417_c0_seq2,988,38.0567,0.27989274,46,181,,1.00E-43,Q8VZB2,Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase PASTICCINO 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase PASTICCINO 2) (AtPAS2) (HACD) (HCD) (Protein PEPINO) (PEP) (Protein tyrosine phosphatase-like protein),Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase PASTICCINO 2) (AtPAS2) (HACD) (HCD) (Protein PEPINO) (PEP) (Protein tyrosine phosphatase-like protein),GO:0005789; GO:0006633; GO:0016021; GO:0016829; GO:0007275; GO:0005634,endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; lyase activity; multicellular organismal development; nucleus,PF04387;,5.00E-39,CHOYP_HACD2.1.1,,,,,,,PAS2_ARATH,Arabidopsis thaliana (Mouse-ear cress),fatty acid biosynthetic process [GO:0006633]; multicellular organism development [GO:0007275] comp138419_c0_seq1,2737,36.6825,0.43895094,0,0,,7.00E-23,Q13490,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (IAP-2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2),GO:0035631; GO:0038061; GO:0035666; GO:0007166; GO:0006921; GO:0005829; GO:0045087; GO:0009898; GO:0070266; GO:0043066; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0000209; GO:0039535; GO:0051726; GO:0045595; GO:0042127; GO:2000116; GO:0050727; GO:0060544; GO:0070424; GO:0034121; GO:0006355; GO:0034138; GO:0034142; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; NIK/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; cell surface receptor signaling pathway; cellular component disassembly involved in execution phase of apoptosis; cytosol; innate immune response; internal side of plasma membrane; necroptosis; negative regulation of apoptotic process; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of RIG-I signaling pathway; regulation of cell cycle; regulation of cell differentiation; regulation of cell proliferation; regulation of cysteine-type endopeptidase activity; regulation of inflammatory response; regulation of necroptosis; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of toll-like receptor signaling pathway; regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_HUMAN,Homo sapiens (Human),"cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp138419_c0_seq2,2354,35.6415,0.41894784,0,0,,4.00E-07,D3ZDI6,E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),GO:0006928; GO:0042632; GO:0005737; GO:0005856; GO:0019898; GO:0010989; GO:0007399; GO:0005886; GO:0045732; GO:0031648; GO:0042787; GO:0032803; GO:0004842; GO:0008270,cellular component movement; cholesterol homeostasis; cytoplasm; cytoskeleton; extrinsic to membrane; negative regulation of low-density lipoprotein particle clearance; nervous system development; plasma membrane; positive regulation of protein catabolic process; protein destabilization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of low-density lipoprotein particle receptor catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF09380;PF00373;PF09379;,,,,,,,,,MYLIP_RAT,Rattus norvegicus (Rat),cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803] comp138419_c0_seq3,2726,36.6838,0.44090726,0,0,,7.00E-41,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,1.00E-30,ruditapes2_c1114,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp138419_c0_seq7,2365,35.6448,0.41668663,0,0,,2.00E-15,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp138421_c0_seq1,709,43.1594,0.29521888,2,17,,2.00E-37,Q3ZBT2,F-box only protein 9,F-box only protein 9,GO:0019005; GO:0031146; GO:0005737; GO:0016567; GO:0032006,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cytoplasm; protein ubiquitination; regulation of TOR signaling cascade,PF12937;,8.00E-22,CHOYP_FBX9.1.1,,,,,,,FBX9_BOVIN,Bos taurus (Bovine),fat cell differentiation [GO:0045444]; innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of TOR signaling [GO:0032006]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp138421_c0_seq6,642,40.1869,0.30978696,0,0,,,,,,,,,2.00E-11,CHOYP_contig_042295,,,,,,,,, comp138422_c0_seq1,4440,46.8018,1.0148538,13,0,,8.00E-52,A6NMZ7,Collagen alpha-6(VI) chain,Collagen alpha-6(VI) chain,GO:0007155; GO:0005581; GO:0030574; GO:0031012; GO:0022617; GO:0005576,cell adhesion; collagen; collagen catabolic process; extracellular matrix; extracellular matrix disassembly; extracellular region,PF01391;PF00092;,,,,,,,,,CO6A6_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574] comp138422_c0_seq2,4482,46.6533,1.01598624,4,0,,1.00E-19,Q5VV43,Dyslexia-associated protein KIAA0319,Dyslexia-associated protein KIAA0319,GO:0005769; GO:0031901; GO:0016021; GO:2000171; GO:0001764; GO:0005886,early endosome; early endosome membrane; integral to membrane; negative regulation of dendrite development; neuron migration; plasma membrane,PF02010;,,,,,,,,,K0319_HUMAN,Homo sapiens (Human),negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764] comp138424_c0_seq1,1396,42.1203,0.70073604,14,80,,2.00E-178,Q99JW2,Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase),Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase),GO:0004046; GO:0006520; GO:0005737; GO:0046872; GO:0008237; GO:0006508,aminoacylase activity; cellular amino acid metabolic process; cytoplasm; metal ion binding; metallopeptidase activity; proteolysis,PF07687;PF01546;,4.00E-99,CHOYP_BRAFLDRAFT_262219.2.2,,,,,,,ACY1_MOUSE,Mus musculus (Mouse),cellular amino acid metabolic process [GO:0006520]; peptide catabolic process [GO:0043171] comp138424_c0_seq2,977,41.1464,0.69777115,4,15,,1.00E-128,Q99JW2,Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase),Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase),GO:0004046; GO:0006520; GO:0005737; GO:0046872; GO:0008237; GO:0006508,aminoacylase activity; cellular amino acid metabolic process; cytoplasm; metal ion binding; metallopeptidase activity; proteolysis,PF07687;PF01546;,,,,,,,,,ACY1_MOUSE,Mus musculus (Mouse),cellular amino acid metabolic process [GO:0006520]; peptide catabolic process [GO:0043171] comp138427_c0_seq1,1457,40.2883,0.86664376,92,965,,,,,,,,,,,5.00E-20,ruditapes_c22382,,,,,,, comp138430_c0_seq1,480,37.2917,0.49524024,85,100,,1.00E-40,Q9QY93,dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21-C6) (XTP3-transactivated gene A protein homolog),dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21-C6) (XTP3-transactivated gene A protein homolog),GO:0005829; GO:0047840; GO:0000287; GO:0009143; GO:0047429; GO:0051289; GO:0032556,cytosol; dCTP diphosphatase activity; magnesium ion binding; nucleoside triphosphate catabolic process; nucleoside-triphosphate diphosphatase activity; protein homotetramerization; pyrimidine deoxyribonucleotide binding,PF12643;,3.00E-31,CHOYP_ZGC_73273.1.1,,,,,,,DCTP1_MOUSE,Mus musculus (Mouse),nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside triphosphate catabolic process [GO:0009143]; protein homotetramerization [GO:0051289] comp138431_c0_seq1,1007,34.1609,0.62088143,0,0,,4.00E-38,Q8T0B1,Nuclear envelope phosphatase-regulatory subunit 1 homolog (Transmembrane protein 188),Nuclear envelope phosphatase-regulatory subunit 1 homolog (Transmembrane protein 188),GO:0071595; GO:0005737; GO:0016021; GO:0006629; GO:0031965; GO:0035307; GO:0010867,Nem1-Spo7 phosphatase complex; cytoplasm; integral to membrane; lipid metabolic process; nuclear membrane; positive regulation of protein dephosphorylation; positive regulation of triglyceride biosynthetic process,PF09771;,,,,,,,,,NEPR1_DROME,Drosophila melanogaster (Fruit fly),lipid metabolic process [GO:0006629]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of triglyceride biosynthetic process [GO:0010867]; sensory perception of pain [GO:0019233] comp138431_c0_seq3,876,35.6164,0.65950955,20,94,,4.00E-55,Q5M8F7,Nuclear envelope phosphatase-regulatory subunit 1 (Transmembrane protein 188),Nuclear envelope phosphatase-regulatory subunit 1 (Transmembrane protein 188),GO:0071595; GO:0005737; GO:0016021; GO:0006629; GO:0031965; GO:0035307; GO:0010867,Nem1-Spo7 phosphatase complex; cytoplasm; integral to membrane; lipid metabolic process; nuclear membrane; positive regulation of protein dephosphorylation; positive regulation of triglyceride biosynthetic process,PF09771;,2.00E-49,CHOYP_NEPR1.1.1,,,,,,,NEPR1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),lipid metabolic process [GO:0006629]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of triglyceride biosynthetic process [GO:0010867] comp138431_c0_seq4,867,32.6413,0.70000093,0,0,,,,,,,,,1.00E-20,CHOYP_LOC100533291.7.7,,,,,,,,, comp138432_c2_seq1,1550,41.1613,0.51413353,0,0,,,,,,,,,3.00E-31,CHOYP_LOC100366482.1.1,,,,,,,,, comp138432_c2_seq2,1919,40.5941,0.45390083,15,0,,1.00E-155,Q8T773,Putative malate dehydrogenase 1B (EC 1.1.1.-),Putative malate dehydrogenase 1B (EC 1.1.1.-),GO:0005975; GO:0045454; GO:0009055; GO:0016615; GO:0006108; GO:0016616; GO:0015035; GO:0006099,"carbohydrate metabolic process; cell redox homeostasis; electron carrier activity; malate dehydrogenase activity; malate metabolic process; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; protein disulfide oxidoreductase activity; tricarboxylic acid cycle",PF02866;PF00056;,,,,,,,,,MDH1B_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),carbohydrate metabolic process [GO:0005975]; cell redox homeostasis [GO:0045454]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] comp138432_c2_seq3,1897,40.485,0.46102503,6,0,,,,,,,,,,,7.00E-45,ruditapes_c20846,,,,,,, comp138432_c2_seq4,1528,41.034,0.52394573,0,0,,2.00E-153,Q8T773,Putative malate dehydrogenase 1B (EC 1.1.1.-),Putative malate dehydrogenase 1B (EC 1.1.1.-),GO:0005975; GO:0045454; GO:0009055; GO:0016615; GO:0006108; GO:0016616; GO:0015035; GO:0006099,"carbohydrate metabolic process; cell redox homeostasis; electron carrier activity; malate dehydrogenase activity; malate metabolic process; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; protein disulfide oxidoreductase activity; tricarboxylic acid cycle",PF02866;PF00056;,,,,,,,,,MDH1B_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),carbohydrate metabolic process [GO:0005975]; cell redox homeostasis [GO:0045454]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] comp138434_c0_seq1,1795,39.6657,0.41300137,176,854,,1.00E-34,Q9VMQ7,Putative elongator complex protein 4 (ELP4),Putative elongator complex protein 4 (ELP4),GO:0033588; GO:0005737; GO:0008607; GO:0006357; GO:0008023; GO:0006351,"Elongator holoenzyme complex; cytoplasm; phosphorylase kinase regulator activity; regulation of transcription from RNA polymerase II promoter; transcription elongation factor complex; transcription, DNA-dependent",PF05625;,,,,,,,,,ELP4_DROME,Drosophila melanogaster (Fruit fly),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp138434_c0_seq2,1775,39.662,0.41795709,85,226,,6.00E-113,Q566Y1,Elongator complex protein 4 (ELP4),Elongator complex protein 4 (ELP4),GO:0033588; GO:0005737; GO:0008607; GO:0006357; GO:0008023; GO:0006351,"Elongator holoenzyme complex; cytoplasm; phosphorylase kinase regulator activity; regulation of transcription from RNA polymerase II promoter; transcription elongation factor complex; transcription, DNA-dependent",PF05625;,4.00E-106,CHOYP_BRAFLDRAFT_124325.1.1,,,,,,,ELP4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp138437_c0_seq1,1526,37.287,0.56875185,169,17,,,,,,,,,,,4.00E-122,ruditapes_c22159,,,,,,, comp138437_c0_seq2,2258,43.9327,0.36767585,575,125,,2.00E-55,Q95LS7,Coiled-coil domain-containing protein 96,Coiled-coil domain-containing protein 96,,,PF13870;,3.00E-141,CHOYP_BRAFLDRAFT_126923.1.1,,,,,,,CCD96_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp138441_c0_seq1,919,38.4113,0.83043296,0,0,,,,,,,,,7.00E-18,CHOYP_DNAH6.1.3,,,,,,,,, comp138441_c0_seq3,929,38.5361,0.84492579,0,0,,,,,,,,,7.00E-18,CHOYP_DNAH6.1.3,,,,,,,,, comp138441_c0_seq4,348,46.5517,0.43509787,4,5,,2.00E-06,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,,,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp138447_c0_seq1,1827,40.613,0.5084581,170,165,,0,Q3UKJ7,"WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]","WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]",GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,0,CHOYP_SMU1.1.1,,,,,,,SMU1_MOUSE,Mus musculus (Mouse), comp138447_c0_seq2,1741,39.7473,0.51368264,4,0,,2.00E-35,Q498M4,WD repeat-containing protein 5,WD repeat-containing protein 5,GO:0005671; GO:0071339; GO:0048188; GO:0043966; GO:0051568; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0042800; GO:0035064; GO:0006355; GO:0001501; GO:0006351,"Ada2/Gcn5/Ada3 transcription activator complex; MLL1 complex; Set1C/COMPASS complex; histone H3 acetylation; histone H3-K4 methylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; histone methyltransferase activity (H3-K4 specific); methylated histone residue binding; regulation of transcription, DNA-dependent; skeletal system development; transcription, DNA-dependent",PF00400;,,,,,,,,,WDR5_RAT,Rattus norvegicus (Rat),"histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]" comp138447_c1_seq1,471,47.983,0.48148365,57,145,,,,,,,,,5.00E-22,CHOYP_LOC100374582.1.1,,,,,,,,, comp138448_c0_seq4,2081,45.3628,0.65437417,12,11,,2.00E-140,Q6AZ28,E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),GO:0003677; GO:0016605; GO:0019789; GO:0030521; GO:0016607; GO:0005634; GO:0050775; GO:0045893; GO:0016925; GO:0060765; GO:0033574; GO:0007283; GO:0006351; GO:0008270,"DNA binding; PML body; SUMO ligase activity; androgen receptor signaling pathway; nuclear speck; nucleus; positive regulation of dendrite morphogenesis; positive regulation of transcription, DNA-dependent; protein sumoylation; regulation of androgen receptor signaling pathway; response to testosterone stimulus; spermatogenesis; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,2.00E-99,CHOYP_PIAS2.1.1,,,,,,,PIAS2_RAT,Rattus norvegicus (Rat),"androgen receptor signaling pathway [GO:0030521]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription, DNA-templated [GO:0045893]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; response to organic substance [GO:0010033]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp138448_c0_seq5,2430,45.0617,0.66016828,20,6,,2.00E-139,Q6AZ28,E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),GO:0003677; GO:0016605; GO:0019789; GO:0030521; GO:0016607; GO:0005634; GO:0050775; GO:0045893; GO:0016925; GO:0060765; GO:0033574; GO:0007283; GO:0006351; GO:0008270,"DNA binding; PML body; SUMO ligase activity; androgen receptor signaling pathway; nuclear speck; nucleus; positive regulation of dendrite morphogenesis; positive regulation of transcription, DNA-dependent; protein sumoylation; regulation of androgen receptor signaling pathway; response to testosterone stimulus; spermatogenesis; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS2_RAT,Rattus norvegicus (Rat),"androgen receptor signaling pathway [GO:0030521]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription, DNA-templated [GO:0045893]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; response to organic substance [GO:0010033]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp138448_c0_seq6,2327,45.1225,0.67040683,0,32,,1.00E-136,O88907,E3 SUMO-protein ligase PIAS1 (EC 6.3.2.-) (DEAD/H box-binding protein 1) (Protein inhibitor of activated STAT protein 1),E3 SUMO-protein ligase PIAS1 (EC 6.3.2.-) (DEAD/H box-binding protein 1) (Protein inhibitor of activated STAT protein 1),GO:0003677; GO:0007259; GO:0016605; GO:0019789; GO:0000122; GO:0016607; GO:0005634; GO:0032436; GO:0033235; GO:0016925; GO:0042127; GO:0003714; GO:0006351; GO:0008270,"DNA binding; JAK-STAT cascade; PML body; SUMO ligase activity; negative regulation of transcription from RNA polymerase II promoter; nuclear speck; nucleus; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein sumoylation; protein sumoylation; regulation of cell proliferation; transcription corepressor activity; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,2.00E-99,CHOYP_PIAS2.1.1,,,6.00E-103,AM858915.p.cg.6,3,,PIAS1_MOUSE,Mus musculus (Mouse),"fat cell differentiation [GO:0045444]; JAK-STAT cascade [GO:0007259]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of cell proliferation [GO:0042127]; transcription, DNA-templated [GO:0006351]" comp138449_c1_seq1,2537,44.7773,0.37896157,377,1616,,0,Q68F70,Integrator complex subunit 4 (Int4),Integrator complex subunit 4 (Int4),GO:0005634,nucleus,,9.00E-117,CHOYP_BRAFLDRAFT_283451.1.1,,,,,,,INT4_XENLA,Xenopus laevis (African clawed frog), comp138450_c0_seq1,2303,41.6848,0.44339482,76,447,,1.00E-174,Q9Z1N2,Origin recognition complex subunit 1,Origin recognition complex subunit 1,GO:0005524; GO:0003677; GO:0006260; GO:0005737; GO:0005664; GO:0005730; GO:0017111; GO:0005886,ATP binding; DNA binding; DNA replication; cytoplasm; nuclear origin of replication recognition complex; nucleolus; nucleoside-triphosphatase activity; plasma membrane,PF00004;PF01426;PF09079;,7.00E-162,CHOYP_ORC1.1.2,,,3.00E-119,AM860854.p.cg.6,3,,ORC1_MOUSE,Mus musculus (Mouse),DNA replication [GO:0006260]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of smooth muscle cell proliferation [GO:0048661] comp138453_c0_seq2,527,33.5863,0.34393037,0,0,,,,,,,,,,,1.00E-21,ruditapes_c12101,,,,,,, comp138453_c0_seq3,798,35.7143,0.44492325,2,17,,2.00E-63,A3KP37,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 (Probable methyltransferase C20orf7 homolog, mitochondrial) (EC 2.1.1.-)","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 (Probable methyltransferase C20orf7 homolog, mitochondrial) (EC 2.1.1.-)",GO:0008168; GO:0005743,methyltransferase activity; mitochondrial inner membrane,PF08241;,,,,,,,,,NDUF5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp138453_c0_seq4,671,38.5991,0.70051664,45,409,,2.00E-14,D9SJ16,Malonyl-[acyl-carrier protein] O-methyltransferase (Malonyl-ACP O-methyltransferase) (EC 2.1.1.197) (Biotin synthesis protein BioC),Malonyl-[acyl-carrier protein] O-methyltransferase (Malonyl-ACP O-methyltransferase) (EC 2.1.1.197) (Biotin synthesis protein BioC),GO:0009102; GO:0010340,biotin biosynthetic process; carboxyl-O-methyltransferase activity,PF08241;,7.00E-35,CHOYP_LOC754687.1.1,,,,,,,BIOC_GALCS,Gallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2)),biotin biosynthetic process [GO:0009102] comp138453_c0_seq5,761,35.2168,0.38977049,2,0,,7.00E-06,Q83E64,Malonyl-[acyl-carrier protein] O-methyltransferase 1 (Malonyl-ACP O-methyltransferase 1) (EC 2.1.1.197) (Biotin synthesis protein BioC 1),Malonyl-[acyl-carrier protein] O-methyltransferase 1 (Malonyl-ACP O-methyltransferase 1) (EC 2.1.1.197) (Biotin synthesis protein BioC 1),GO:0009102; GO:0010340,biotin biosynthetic process; carboxyl-O-methyltransferase activity,PF08241;,,,,,,,,,BIOC1_COXBU,Coxiella burnetii (strain RSA 493 / Nine Mile phase I),biotin biosynthetic process [GO:0009102]; methylation [GO:0032259] comp138454_c0_seq11,1156,40.8304,1.01151489,0,0,,,,,,,,,9.00E-18,CHOYP_LOC582782.3.4,,,,,,,,, comp138454_c0_seq2,1396,39.8997,0.92526408,5,0,,,,,,,,,2.00E-20,CHOYP_LOC582782.3.4,,,,,,,,, comp138454_c0_seq9,1171,39.9658,1.02239744,3,0,,,,,,,,,9.00E-18,CHOYP_LOC582782.3.4,,,,,,,,, comp138457_c0_seq1,2568,44.1199,0.53291057,182,313,,2.00E-43,Q5XI03,Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45),Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45),GO:0005813; GO:0005737; GO:0000922,centrosome; cytoplasm; spindle pole,,1.00E-70,CHOYP_LOC100372020.1.1,,,,,,,CEP95_RAT,Rattus norvegicus (Rat), comp138461_c0_seq2,1577,35.3202,0.49093899,7,39,,2.00E-37,P49963,Signal recognition particle 19 kDa protein (SRP19),Signal recognition particle 19 kDa protein (SRP19),GO:0008312; GO:0006614; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; signal recognition particle, endoplasmic reticulum targeting",PF01922;,,,,,,,,,SRP19_DROME,Drosophila melanogaster (Fruit fly),SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp138463_c0_seq1,1363,42.113,0.35109414,82,197,,3.00E-165,Q14746,Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein),Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein),GO:0000139; GO:0007030; GO:0005795; GO:0017119; GO:0006891; GO:0006886; GO:0009312; GO:0006486; GO:0008565,Golgi membrane; Golgi organization; Golgi stack; Golgi transport complex; intra-Golgi vesicle-mediated transport; intracellular protein transport; oligosaccharide biosynthetic process; protein glycosylation; protein transporter activity,PF06148;PF12022;,2.00E-122,CHOYP_COG2.1.2,,,,,,,COG2_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891] comp138463_c1_seq1,585,41.5385,0.51647609,26,113,,5.00E-31,Q921L5,Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein),Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein),GO:0000139; GO:0007030; GO:0005795; GO:0017119; GO:0006891; GO:0008565,Golgi membrane; Golgi organization; Golgi stack; Golgi transport complex; intra-Golgi vesicle-mediated transport; protein transporter activity,PF06148;PF12022;,,,,,,,,,COG2_MOUSE,Mus musculus (Mouse),Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891] comp138468_c0_seq1,1215,45.5967,1.01279815,69,248,,8.00E-19,Q9NH13,Exoskeleton protein RP43,Exoskeleton protein RP43,GO:0006033; GO:0030198,chitin localization; extracellular matrix organization,PF00431;,,,,,,,,,RP43_RIFPA,Riftia pachyptila (Vent tube worm),chitin localization [GO:0006033]; extracellular matrix organization [GO:0030198] comp138468_c1_seq2,1945,41.6452,0.95422379,130,950,,6.00E-28,P00734,Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain],Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain],GO:0005796; GO:0006953; GO:0007597; GO:0005509; GO:0007166; GO:0051480; GO:0005788; GO:0005615; GO:0042730; GO:0008083; GO:0050900; GO:0048712; GO:0051918; GO:0010544; GO:0045861; GO:0017187; GO:0005886; GO:0030168; GO:0030307; GO:0008284; GO:0032967; GO:0014068; GO:1900738; GO:0001934; GO:2000379; GO:0051281; GO:0043687; GO:0006508; GO:0008360; GO:0010468; GO:0004252; GO:0070053,"Golgi lumen; acute-phase response; blood coagulation, intrinsic pathway; calcium ion binding; cell surface receptor signaling pathway; cytosolic calcium ion homeostasis; endoplasmic reticulum lumen; extracellular space; fibrinolysis; growth factor activity; leukocyte migration; negative regulation of astrocyte differentiation; negative regulation of fibrinolysis; negative regulation of platelet activation; negative regulation of proteolysis; peptidyl-glutamic acid carboxylation; plasma membrane; platelet activation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of protein phosphorylation; positive regulation of reactive oxygen species metabolic process; positive regulation of release of sequestered calcium ion into cytosol; post-translational protein modification; proteolysis; regulation of cell shape; regulation of gene expression; serine-type endopeptidase activity; thrombospondin receptor activity",PF00594;PF00051;PF09396;PF00089;,,,1.00E-17,ruditapes2_c1595,,,,,THRB_HUMAN,Homo sapiens (Human),"acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cellular response to mechanical stimulus [GO:0071260]; ER to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; peptidyl-glutamic acid carboxylation [GO:0017187]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900738]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to inactivity [GO:0014854]; response to wounding [GO:0009611]; signal peptide processing [GO:0006465]" comp138470_c0_seq1,759,36.8906,0.46819733,25,338,,1.00E-09,P54622,"Single-stranded DNA-binding protein, mitochondrial (Dm mtSSB) (Mt-SSB) (MtSSB) (Protein low power)","Single-stranded DNA-binding protein, mitochondrial (Dm mtSSB) (Mt-SSB) (MtSSB) (Protein low power)",GO:0006264; GO:0000262; GO:0003697,mitochondrial DNA replication; mitochondrial chromosome; single-stranded DNA binding,PF00436;,,,,,,,,,SSBP_DROME,Drosophila melanogaster (Fruit fly),mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] comp138470_c1_seq3,3310,35.861,1.01596168,0,0,,,,,,,,,,,3.00E-39,ruditapes_c21032,,,,,,, comp138471_c0_seq1,2533,40.9396,0.86826084,41207,25,male>female,7.00E-08,Q6P132,Tax1-binding protein 1 homolog B,Tax1-binding protein 1 homolog B,GO:0006915,apoptotic process,PF07888;,,,,,,,,,TXB1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915] comp138475_c3_seq1,1574,40.4066,0.41607414,54,276,,3.00E-111,Q9NWY4,UPF0609 protein C4orf27,Histone PARylation factor 1,GO:0005634,nucleus,PF10228;,,,,,,,,,CD027_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; regulation of protein ADP-ribosylation [GO:0010835] comp138475_c3_seq2,1494,41.0308,0.42394714,29,86,,1.00E-96,A8MVJ9,Putative UPF0609 protein C4orf27-like,Putative UPF0609 protein C4orf27-like,,,PF10228;,5.00E-60,CHOYP_LOC584680.1.1,,,,,,,YI028_HUMAN,Homo sapiens (Human), comp138477_c0_seq2,1556,38.3676,0.28148528,1026,2086,,5.00E-46,Q9H6D7,HAUS augmin-like complex subunit 4,HAUS augmin-like complex subunit 4,GO:0070652; GO:0051301; GO:0005813; GO:0051297; GO:0005737; GO:0005874; GO:0007067; GO:0005819; GO:0051225,HAUS complex; cell division; centrosome; centrosome organization; cytoplasm; microtubule; mitosis; spindle; spindle assembly,PF14735;,1.00E-23,CHOYP_BRAFLDRAFT_275667.1.1,,,,,,,HAUS4_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp138479_c0_seq1,2677,41.1281,0.56451796,20,6,,0,Q8WXW3,Progesterone-induced-blocking factor 1,Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90),GO:0005813,centrosome,,0,CHOYP_LOC100377791.1.1,,,,,,,PIBF1_HUMAN,Homo sapiens (Human),activation of JAK1 kinase activity [GO:0010531]; immune system process [GO:0002376]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of tyrosine phosphorylation of Stat4 protein [GO:0042521]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of tyrosine phosphorylation of Stat6 protein [GO:0042526]; protein localization to centrosome [GO:0071539] comp138479_c0_seq2,2712,40.9661,0.56098968,5,76,,0,Q8WXW3,Progesterone-induced-blocking factor 1,Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90),GO:0005813,centrosome,,0,CHOYP_LOC100377791.1.1,,,,,,,PIBF1_HUMAN,Homo sapiens (Human),activation of JAK1 kinase activity [GO:0010531]; immune system process [GO:0002376]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of tyrosine phosphorylation of Stat4 protein [GO:0042521]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of tyrosine phosphorylation of Stat6 protein [GO:0042526]; protein localization to centrosome [GO:0071539] comp138482_c0_seq2,1334,38.2309,0.8808287,1,78,,1.00E-68,P36397,ADP-ribosylation factor 1 (AtARF1),ADP-ribosylation factor 1 (AtARF1),GO:0005525; GO:0005794; GO:0005768; GO:0016004; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; endosome; phospholipase activator activity; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,,,,,,,,,ARF1_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp138482_c0_seq3,750,46.2667,0.7624379,0,0,,,,,,,,,7.00E-36,CHOYP_ACT.15.27,,,,,,,,, comp138482_c0_seq4,859,45.2852,0.77040117,1,15,,5.00E-73,P34727,ADP-ribosylation factor,ADP-ribosylation factor,GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,8.00E-61,CHOYP_LOC100637317.2.4,,,,,,,ARF_AJECA,Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp138487_c0_seq1,1997,45.6685,0.94338893,70,557,,3.00E-24,Q80T79,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_MOUSE,Mus musculus (Mouse), comp138488_c0_seq1,1374,36.0262,0.48712827,224,465,,2.00E-26,A2BHB7,"Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)","Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)",GO:0005524; GO:0016874; GO:0005739; GO:0006450; GO:0006412,ATP binding; ligase activity; mitochondrion; regulation of translational fidelity; translation,PF02686;,,,,,,,,,GATC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]; regulation of translational fidelity [GO:0006450] comp138488_c0_seq2,1119,36.6399,0.53081935,63,316,,3.00E-37,C3XVM1,"Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)","Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)",GO:0005524; GO:0016874; GO:0005739; GO:0006450; GO:0006412,ATP binding; ligase activity; mitochondrion; regulation of translational fidelity; translation,PF02686;,,,7.00E-17,ruditapes_c13184,,,,,GATC_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]; regulation of translational fidelity [GO:0006450] comp138493_c1_seq1,2518,45.1549,0.6485422,17,13,,5.00E-131,Q9UHV7,Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250),Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250),GO:0001104; GO:0030521; GO:0030374; GO:0016592; GO:0045944; GO:0004872; GO:0046966; GO:0006367; GO:0042809,RNA polymerase II transcription cofactor activity; androgen receptor signaling pathway; ligand-dependent nuclear receptor transcription coactivator activity; mediator complex; positive regulation of transcription from RNA polymerase II promoter; receptor activity; thyroid hormone receptor binding; transcription initiation from RNA polymerase II promoter; vitamin D receptor binding,PF06333;PF11597;,2.00E-43,CHOYP_PHUM_PHUM174820.1.1,,,,,,,MED13_HUMAN,Homo sapiens (Human),"androgen receptor signaling pathway [GO:0030521]; cholesterol homeostasis [GO:0042632]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; negative regulation of thyroid hormone receptor activity [GO:1904168]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription initiation from RNA polymerase II promoter [GO:0006367]; triglyceride homeostasis [GO:0070328]" comp138493_c1_seq3,2358,46.4801,0.64693264,0,0,,1.00E-131,Q9UHV7,Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250),Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250),GO:0001104; GO:0030521; GO:0030374; GO:0016592; GO:0045944; GO:0004872; GO:0046966; GO:0006367; GO:0042809,RNA polymerase II transcription cofactor activity; androgen receptor signaling pathway; ligand-dependent nuclear receptor transcription coactivator activity; mediator complex; positive regulation of transcription from RNA polymerase II promoter; receptor activity; thyroid hormone receptor binding; transcription initiation from RNA polymerase II promoter; vitamin D receptor binding,PF06333;PF11597;,2.00E-43,CHOYP_PHUM_PHUM174820.1.1,,,,,,,MED13_HUMAN,Homo sapiens (Human),"androgen receptor signaling pathway [GO:0030521]; cholesterol homeostasis [GO:0042632]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; negative regulation of thyroid hormone receptor activity [GO:1904168]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription initiation from RNA polymerase II promoter [GO:0006367]; triglyceride homeostasis [GO:0070328]" comp138494_c0_seq1,3356,38.8856,0.51113677,284,92,,5.00E-15,Q2T9Z6,Coiled-coil domain-containing protein 175,Coiled-coil domain-containing protein 175,,,,3.00E-98,CHOYP_LOC577287.1.2,,,,,,,CN038_BOVIN,Bos taurus (Bovine), comp138500_c1_seq1,1758,37.0307,0.33926757,57,267,,,,,,,,,2.00E-143,CHOYP_LOC100372693.1.1,,,,,,,,, comp138500_c1_seq2,1744,36.9839,0.34206978,92,270,,2.00E-143,P13804,"Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF)","Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF)",GO:0009055; GO:0050660; GO:0005759; GO:0016491; GO:0022904; GO:0044281,electron carrier activity; flavin adenine dinucleotide binding; mitochondrial matrix; oxidoreductase activity; respiratory electron transport chain; small molecule metabolic process,PF01012;PF00766;,2.00E-143,CHOYP_LOC100372693.1.1,5.00E-103,ruditapes2_c1754,,,,,ETFA_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; respiratory electron transport chain [GO:0022904] comp138501_c0_seq2,2751,35.2963,0.46572424,28,31225,female>male,3.00E-21,P91753,Mitotic apparatus protein p62,Mitotic apparatus protein p62,GO:0051301; GO:0007067; GO:0003676; GO:0005634,cell division; mitosis; nucleic acid binding; nucleus,PF16276;,7.00E-11,CHOYP_CATA.3.3,7.00E-110,ruditapes_c11557,,,,,MP62_LYTPI,Lytechinus pictus (Painted sea urchin),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp138502_c0_seq1,2594,45.7209,0.4556249,0,12,,,,,,,,,7.00E-150,CHOYP_TFP11.1.1,3.00E-51,ruditapes_c15300,,,,,,, comp138502_c0_seq2,2614,45.6771,0.46052732,14,143,,0,Q06AK6,Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1),Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1),GO:0003677; GO:0008380; GO:0031214; GO:0005737; GO:0006397; GO:0006355; GO:0005681,"DNA binding; RNA splicing; biomineral tissue development; cytoplasm; mRNA processing; regulation of transcription, DNA-dependent; spliceosomal complex",PF01585;PF07842;PF12457;,1.00E-20,CHOYP_AAEL_AAEL008445.1.1,,,,,,,TFP11_PIG,Sus scrofa (Pig),"biomineral tissue development [GO:0031214]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal complex disassembly [GO:0000390]" comp138504_c0_seq3,1499,39.8266,0.55331437,6,96,,1.00E-66,F1R6N4,Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41),Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41),GO:0016831; GO:0005829; GO:0004492,carboxy-lyase activity; cytosol; methylmalonyl-CoA decarboxylase activity,PF00378;,,,,,,,,,ECHD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),metabolic process [GO:0008152] comp138504_c0_seq4,1189,40.7065,0.50764344,1,14,,7.00E-68,F1R6N4,Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41),Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41),GO:0016831; GO:0005829; GO:0004492,carboxy-lyase activity; cytosol; methylmalonyl-CoA decarboxylase activity,PF00378;,,,,,,,,,ECHD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),metabolic process [GO:0008152] comp138505_c0_seq2,1089,47.1074,0.54872514,36,74,,3.00E-26,O95789,Zinc finger MYM-type protein 6 (Transposon-derived Buster2 transposase-like protein) (Zinc finger protein 258),Zinc finger MYM-type protein 6 (Transposon-derived Buster2 transposase-like protein) (Zinc finger protein 258),GO:0003677; GO:0007010; GO:0007275; GO:0005634; GO:0022604; GO:0008270,DNA binding; cytoskeleton organization; multicellular organismal development; nucleus; regulation of cell morphogenesis; zinc ion binding,PF14291;PF06467;,,,,,,,,,ZMYM6_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; multicellular organism development [GO:0007275]; regulation of cell morphogenesis [GO:0022604] comp138505_c0_seq3,2039,42.0795,0.47669779,124,335,,2.00E-55,Q14202,Zinc finger MYM-type protein 3 (Zinc finger protein 261),Zinc finger MYM-type protein 3 (Zinc finger protein 261),GO:0003677; GO:0007010; GO:0007275; GO:0005634; GO:0022604; GO:0008270,DNA binding; cytoskeleton organization; multicellular organismal development; nucleus; regulation of cell morphogenesis; zinc ion binding,PF12012;PF06467;,1.00E-132,CHOYP_LOC100121687.1.1,,,,,,,ZMYM3_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; multicellular organism development [GO:0007275]; regulation of cell morphogenesis [GO:0022604] comp138505_c1_seq4,1153,42.4111,0.42663203,0,15,,,,,,,,,9.00E-18,CHOYP_LOC100121687.1.1,,,,,,,,, comp138506_c2_seq1,3077,38.414,0.47577444,336,313,,4.00E-60,Q76LT8,Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Synaptic ubiquitin-specific protease) (synUSP) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48),Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Synaptic ubiquitin-specific protease) (synUSP) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48),GO:0008234; GO:0005737; GO:0045121; GO:0005634; GO:0045211; GO:0004221; GO:0006511,cysteine-type peptidase activity; cytoplasm; membrane raft; nucleus; postsynaptic membrane; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,3.00E-22,CHOYP_UBP48.1.1,,,,,,,UBP48_RAT,Rattus norvegicus (Rat),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138508_c1_seq1,1307,37.4139,0.38092324,350,621,,,,,,,,,4.00E-67,CHOYP_RFA2.1.1,,,,,,,,, comp138508_c1_seq2,1013,40.5726,0.39466809,111,240,,3.00E-66,P15927,Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34),Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34),GO:0000730; GO:0005662; GO:0006271; GO:0000082; GO:0016605; GO:0005654; GO:0000718; GO:0006297; GO:0010569; GO:0003697; GO:0000722; GO:0032201; GO:0006283,"DNA recombinase assembly; DNA replication factor A complex; DNA strand elongation involved in DNA replication; G1/S transition of mitotic cell cycle; PML body; nucleoplasm; nucleotide-excision repair, DNA damage removal; nucleotide-excision repair, DNA gap filling; regulation of double-strand break repair via homologous recombination; single-stranded DNA binding; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair",PF08784;,3.00E-67,CHOYP_RFA2.1.1,3.00E-134,ruditapes2_c2584,,,,,RFA2_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; mitotic G1 DNA damage checkpoint [GO:0031571]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cellular response to heat [GO:1900034]; regulation of DNA damage checkpoint [GO:2000001]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp138510_c0_seq1,1212,36.0561,0.62536561,8,5,,2.00E-36,Q6DGB6,Coiled-coil domain-containing protein 103 (Protein schmalhans),Coiled-coil domain-containing protein 103 (Protein schmalhans),GO:0070286; GO:0030030; GO:0035085; GO:0003341; GO:0003146; GO:0001947,axonemal dynein complex assembly; cell projection organization; cilium axoneme; cilium movement; heart jogging; heart looping,PF15867;PF13877;,,,,,,,,,CC103_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; heart jogging [GO:0003146]; heart looping [GO:0001947] comp138510_c0_seq2,1200,36.1667,0.62846721,3,7,,6.00E-42,Q9D9P2,Coiled-coil domain-containing protein 103,Coiled-coil domain-containing protein 103,GO:0030030; GO:0005929; GO:0003341; GO:0005737; GO:0071907; GO:0001947; GO:0036159; GO:0036158,cell projection organization; cilium; cilium movement; cytoplasm; determination of digestive tract left/right asymmetry; heart looping; inner dynein arm assembly; outer dynein arm assembly,PF15867;PF13877;,3.00E-11,CHOYP_BRAFLDRAFT_118362.1.1,,,,,,,CC103_MOUSE,Mus musculus (Mouse),axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158] comp138511_c0_seq1,1125,45.0667,0.32589426,3,16,,4.00E-112,Q53FA7,Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein),Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein),GO:0006739; GO:0070402; GO:0003960; GO:0008631; GO:0048038; GO:0008270,NADP metabolic process; NADPH binding; NADPH:quinone reductase activity; intrinsic apoptotic signaling pathway in response to oxidative stress; quinone binding; zinc ion binding,PF08240;PF00107;,,,,,,,,,QORX_HUMAN,Homo sapiens (Human),NADP metabolic process [GO:0006739]; regulation of apoptotic process [GO:0042981] comp138511_c0_seq3,1154,44.974,0.2843604,2,27,,7.00E-117,Q53FA7,Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein),Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein),GO:0006739; GO:0070402; GO:0003960; GO:0008631; GO:0048038; GO:0008270,NADP metabolic process; NADPH binding; NADPH:quinone reductase activity; intrinsic apoptotic signaling pathway in response to oxidative stress; quinone binding; zinc ion binding,PF08240;PF00107;,3.00E-49,CHOYP_BRAFLDRAFT_57258.2.3,,,,,,,QORX_HUMAN,Homo sapiens (Human),NADP metabolic process [GO:0006739]; regulation of apoptotic process [GO:0042981] comp138514_c0_seq1,1135,38.4141,1.04637744,1201,125,,1.00E-21,Q5RH71,Tetraspanin-33 (Tspan-33),Tetraspanin-33 (Tspan-33),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747] comp138519_c0_seq2,2448,40.2778,0.78493603,6,17,,6.00E-77,Q9WU40,Inner nuclear membrane protein Man1 (LEM domain-containing protein 3),Inner nuclear membrane protein Man1 (LEM domain-containing protein 3),GO:0003677; GO:0016021; GO:0005639; GO:0005635; GO:0000166; GO:0051726; GO:0035914,DNA binding; integral to membrane; integral to nuclear inner membrane; nuclear envelope; nucleotide binding; regulation of cell cycle; skeletal muscle cell differentiation,PF03020;PF09402;,2.00E-49,CHOYP_LEMD3.1.1,,,,,,,MAN1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; blood vessel endothelial cell migration involved in intussusceptive angiogenesis [GO:0002044]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleus organization [GO:0006997]; regulation of cell cycle [GO:0051726]; regulation of extracellular matrix organization [GO:1903053]; skeletal muscle cell differentiation [GO:0035914] comp138521_c2_seq1,1421,39.3385,0.52816441,57,533,,7.00E-83,Q3B8G8,Mediator of RNA polymerase II transcription subunit 27-B (Cofactor required for Sp1 transcriptional activation subunit 8-B) (CRSP complex subunit 8-B) (Mediator complex subunit 27-B),Mediator of RNA polymerase II transcription subunit 27-B (Cofactor required for Sp1 transcriptional activation subunit 8-B) (CRSP complex subunit 8-B) (Mediator complex subunit 27-B),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11571;,,,,,,,,,MD27B_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138524_c0_seq1,3347,42.6651,0.54611814,7816,92,,9.00E-61,Q5XIN9,Coiled-coil domain-containing protein 81,Coiled-coil domain-containing protein 81,GO:0003677,DNA binding,PF14908;,5.00E-90,CHOYP_LOC100373351.2.3,,,,,,,CCD81_RAT,Rattus norvegicus (Rat), comp138533_c0_seq1,548,43.2482,0.82115658,18,42,,,,,,,,,3.00E-38,CHOYP_LOC100369049.1.1,2.00E-39,ruditapes2_c2326,,,,,,, comp138533_c0_seq3,1735,42.4784,0.60272454,102,176,,6.00E-96,Q9BQK8,Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like),Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like),GO:0005789; GO:0006631; GO:0005634; GO:0008195; GO:0006656; GO:0006646,endoplasmic reticulum membrane; fatty acid metabolic process; nucleus; phosphatidate phosphatase activity; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process,PF16876;PF04571;PF08235;,6.00E-60,CHOYP_DWIL_GK23042.1.1,,,,,,,LPIN3_HUMAN,Homo sapiens (Human),fatty acid catabolic process [GO:0009062]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; triglyceride biosynthetic process [GO:0019432] comp138535_c2_seq2,332,43.3735,0.12969933,3,0,,3.00E-21,Q0VBY3,Hydroxyacylglutathione hydrolase-like protein (EC 3.1.2.-),Hydroxyacylglutathione hydrolase-like protein (EC 3.1.2.-),GO:0006750; GO:0004416; GO:0008270,glutathione biosynthetic process; hydroxyacylglutathione hydrolase activity; zinc ion binding,PF00753;,,,,,,,,,HAGHL_BOVIN,Bos taurus (Bovine), comp138535_c5_seq1,740,41.0811,0.52413889,31,538,,2.00E-78,Q5ZI23,"Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II)","Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II)",GO:0019853; GO:0006750; GO:0004416; GO:0005759; GO:0008270,L-ascorbic acid biosynthetic process; glutathione biosynthetic process; hydroxyacylglutathione hydrolase activity; mitochondrial matrix; zinc ion binding,PF16123;PF00753;,3.00E-34,CHOYP_BRAFLDRAFT_104472.1.1,4.00E-55,ruditapes2_c285,,,,,GLO2_CHICK,Gallus gallus (Chicken),L-ascorbic acid biosynthetic process [GO:0019853]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] comp138538_c0_seq2,1742,37.8301,0.38744108,148,1073,,6.00E-111,Q08DB5,Syntaxin-5,Syntaxin-5,GO:0000139; GO:0033116; GO:0016021; GO:0006886; GO:0042147,"Golgi membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; intracellular protein transport; retrograde transport, endosome to Golgi",PF05739;PF11416;,3.00E-102,CHOYP_LOC100372966.1.1,,,,,,,STX5_BOVIN,Bos taurus (Bovine),early endosome to Golgi transport [GO:0034498]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; regulation of Golgi organization [GO:1903358]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] comp138539_c0_seq1,1833,38.3524,0.65647235,75,1346,,3.00E-120,P25975,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08246;PF00112;,6.00E-60,CHOYP_LOC575203.5.6,3.00E-37,ruditapes_lrc16077,,,,,CATL1_BOVIN,Bos taurus (Bovine),decidualization [GO:0046697]; hair follicle morphogenesis [GO:0031069]; negative regulation of keratinocyte proliferation [GO:0010839]; protein autoprocessing [GO:0016540]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of actin cytoskeleton reorganization [GO:2000249] comp138539_c0_seq3,1909,36.7732,0.38327449,117,3335,,4.00E-124,Q26636,Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],GO:0030154; GO:0008234; GO:0005764; GO:0007275; GO:0006508,cell differentiation; cysteine-type peptidase activity; lysosome; multicellular organismal development; proteolysis,PF08246;PF00112;,9.00E-65,CHOYP_LOC575203.5.6,2.00E-26,ruditapes2_lrc4931,,,,,CATL_SARPE,Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp138539_c0_seq4,2078,40.1829,0.99845531,111,245,,2.00E-108,P06797,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) (p39 cysteine proteinase) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) (p39 cysteine proteinase) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],GO:0060008; GO:0004177; GO:0048102; GO:0009267; GO:0004197; GO:0046697; GO:0009897; GO:0042393; GO:0005764; GO:0005902; GO:0010259; GO:0021675; GO:0043005; GO:0005730; GO:0042277; GO:0043204; GO:0016485; GO:0006508; GO:2000249; GO:0051384; GO:0009749; GO:0034698; GO:0007283,Sertoli cell differentiation; aminopeptidase activity; autophagic cell death; cellular response to starvation; cysteine-type endopeptidase activity; decidualization; external side of plasma membrane; histone binding; lysosome; microvillus; multicellular organismal aging; nerve development; neuron projection; nucleolus; peptide binding; perikaryon; protein processing; proteolysis; regulation of actin cytoskeleton reorganization; response to glucocorticoid stimulus; response to glucose stimulus; response to gonadotropin stimulus; spermatogenesis,PF08246;PF00112;,,,2.00E-148,ruditapes_c2904,,,,,CATL1_MOUSE,Mus musculus (Mouse),autophagic cell death [GO:0048102]; cell communication [GO:0007154]; cellular response to starvation [GO:0009267]; decidualization [GO:0046697]; hair follicle morphogenesis [GO:0031069]; male gonad development [GO:0008584]; multicellular organism aging [GO:0010259]; negative regulation of keratinocyte proliferation [GO:0010839]; nerve development [GO:0021675]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of actin cytoskeleton reorganization [GO:2000249]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to gonadotropin [GO:0034698]; response to organic cyclic compound [GO:0014070]; Sertoli cell differentiation [GO:0060008]; spermatogenesis [GO:0007283] comp138539_c0_seq5,2089,38.5831,0.76571056,117,250,,6.00E-70,Q9STL4,KDEL-tailed cysteine endopeptidase CEP2 (EC 3.4.22.-),KDEL-tailed cysteine endopeptidase CEP2 (EC 3.4.22.-),GO:0008234; GO:0005783; GO:0006508,cysteine-type peptidase activity; endoplasmic reticulum; proteolysis,PF08246;PF00112;,6.00E-42,CHOYP_LOC659226.3.3,7.00E-77,ruditapes_c4044,,,,,CEP2_ARATH,Arabidopsis thaliana (Mouse-ear cress),proteolysis involved in cellular protein catabolic process [GO:0051603] comp138539_c0_seq6,2015,40.0993,0.98359708,4,170,,8.00E-114,P25975,Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain],GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08246;PF00112;,1.00E-69,CHOYP_NEMVEDRAFT_V1G180651.1.2,8.00E-108,ruditapes_lrc13797,,,,,CATL1_BOVIN,Bos taurus (Bovine),decidualization [GO:0046697]; hair follicle morphogenesis [GO:0031069]; negative regulation of keratinocyte proliferation [GO:0010839]; protein autoprocessing [GO:0016540]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of actin cytoskeleton reorganization [GO:2000249] comp138539_c0_seq7,2154,38.5794,0.79357628,0,0,,4.00E-83,Q40143,Cysteine proteinase 3 (EC 3.4.22.-),Cysteine proteinase 3 (EC 3.4.22.-),GO:0008234; GO:0006508; GO:0005773,cysteine-type peptidase activity; proteolysis; vacuole,PF08246;PF00112;,1.00E-43,CHOYP_LOC659226.1.3,9.00E-76,ruditapes_lrc34795,,,,,CYSP3_SOLLC,Solanum lycopersicum (Tomato) (Lycopersicon esculentum),immune response [GO:0006955]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp138540_c2_seq1,2939,40.524,0.79554527,110,909,,0,Q9I9M5,Frizzled-1 (Fz-1) (Xfz1),Frizzled-1 (Fz-1) (Xfz1),GO:0004930; GO:0016055; GO:0042813; GO:0016021; GO:0007275; GO:0005886,G-protein coupled receptor activity; Wnt receptor signaling pathway; Wnt-activated receptor activity; integral to membrane; multicellular organismal development; plasma membrane,PF01534;PF01392;,3.00E-142,CHOYP_FZD7A.1.1,,,,,,,FZD1_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275] comp138541_c0_seq1,838,36.1575,0.29477424,108,540,,,,,,,,,3.00E-53,CHOYP_LTOR2.2.2,,,,,,,,, comp138541_c0_seq2,851,36.4277,0.28638695,78,327,,8.00E-65,B5FYY5,Ragulator complex protein LAMTOR2 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2),Ragulator complex protein LAMTOR2 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2),GO:0071986; GO:0000186; GO:0016049; GO:0034613; GO:0071230; GO:0005085; GO:0005765; GO:0032008,Ragulator complex; activation of MAPKK activity; cell growth; cellular protein localization; cellular response to amino acid stimulus; guanyl-nucleotide exchange factor activity; lysosomal membrane; positive regulation of TOR signaling cascade,PF03259;,3.00E-54,CHOYP_LTOR2.1.2,2.00E-84,ruditapes_c3891,,,,,LTOR2_TAEGU,Taeniopygia guttata (Zebra finch) (Poephila guttata),cell growth [GO:0016049]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008] comp138546_c0_seq1,2236,40.6977,0.36289057,13,21,,2.00E-52,Q07230,Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29),Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29),GO:0003677; GO:0030154; GO:0046872; GO:0007275; GO:0005634; GO:0003700; GO:0007283; GO:0006351,"DNA binding; cell differentiation; metal ion binding; multicellular organismal development; nucleus; sequence-specific DNA binding transcription factor activity; spermatogenesis; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSCA2_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp138546_c0_seq2,2248,40.6139,0.35152304,20,58,,1.00E-46,P17036,Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25),Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25),GO:0003677; GO:0030154; GO:0045321; GO:0007275; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; cell differentiation; leukocyte activation; multicellular organismal development; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZNF3_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; leukocyte activation [GO:0045321]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138546_c0_seq3,1729,40.3123,0.36148316,0,10,,6.00E-29,Q24732,Protein glass,Protein glass,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0050896; GO:0006351; GO:0007601,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; response to stimulus; transcription, DNA-dependent; visual perception",PF00096;,8.00E-14,CHOYP_ZBT24.1.2,,,,,,,GLAS_DROVI,Drosophila virilis (Fruit fly),"regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp138547_c0_seq2,2444,33.1015,0.4150217,17,107,,1.00E-88,Q2KJF9,General transcription factor IIE subunit 2 (Transcription initiation factor IIE subunit beta) (TFIIE-beta),General transcription factor IIE subunit 2 (Transcription initiation factor IIE subunit beta) (TFIIE-beta),GO:0003677; GO:0006355; GO:0005673; GO:0006367,"DNA binding; regulation of transcription, DNA-dependent; transcription factor TFIIE complex; transcription initiation from RNA polymerase II promoter",PF02186;,1.00E-38,CHOYP_T2EB.1.1,,,,,,,T2EB_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp13854_c0_seq1,221,46.1538,0.45642382,1,3,,,,,,,,,6.00E-17,CHOYP_LOC100375672.1.1,,,,,,,,, comp138551_c0_seq1,1810,39.9448,0.30767933,62,665,,1.00E-144,Q0R4F1,ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1),ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006310; GO:0006281; GO:0005739; GO:0005634; GO:0000723,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA recombination; DNA repair; mitochondrion; nucleus; telomere maintenance,PF02689;PF05970;,6.00E-73,CHOYP_PIF1.1.1,,,,,,,PIF1_XENLA,Xenopus laevis (African clawed frog),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] comp138553_c0_seq1,1461,41.6838,0.36337522,110,682,,2.00E-141,Q05B63,tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog),tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog),GO:0008168; GO:0000049; GO:0008033,methyltransferase activity; tRNA binding; tRNA processing,PF01170;,4.00E-30,CHOYP_TRM11.1.1,6.00E-57,ruditapes_c19895,,,,,TRM11_BOVIN,Bos taurus (Bovine), comp138555_c1_seq1,1393,35.1041,0.44560742,0,0,,,,,,,,,3.00E-81,CHOYP_KLC2.1.1,7.00E-18,ruditapes_c24994,,,,,,, comp138555_c1_seq11,2246,37.9786,0.60975257,0,0,,2.00E-156,P46822,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0048675; GO:0005737; GO:0051295; GO:0016938; GO:0040011; GO:0005874; GO:0003777; GO:0002119; GO:0005635; GO:0040038; GO:0048489,axon extension; cytoplasm; establishment of meiotic spindle localization; kinesin I complex; locomotion; microtubule; microtubule motor activity; nematode larval development; nuclear envelope; polar body extrusion after meiotic divisions; synaptic vesicle transport,PF13374;,,,,,,,,,KLC_CAEEL,Caenorhabditis elegans,axon extension [GO:0048675]; establishment of meiotic spindle localization [GO:0051295]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; polar body extrusion after meiotic divisions [GO:0040038]; synaptic vesicle transport [GO:0048489] comp138555_c1_seq13,2219,37.7197,0.61361293,0,17,,2.00E-156,P46822,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0048675; GO:0005737; GO:0051295; GO:0016938; GO:0040011; GO:0005874; GO:0003777; GO:0002119; GO:0005635; GO:0040038; GO:0048489,axon extension; cytoplasm; establishment of meiotic spindle localization; kinesin I complex; locomotion; microtubule; microtubule motor activity; nematode larval development; nuclear envelope; polar body extrusion after meiotic divisions; synaptic vesicle transport,PF13374;,1.00E-178,CHOYP_KLC2.1.1,,,,,,,KLC_CAEEL,Caenorhabditis elegans,axon extension [GO:0048675]; establishment of meiotic spindle localization [GO:0051295]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; polar body extrusion after meiotic divisions [GO:0040038]; synaptic vesicle transport [GO:0048489] comp138555_c1_seq14,1448,42.8867,0.85095178,1,10,,0,P46825,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0005737; GO:0005871; GO:0005874; GO:0003777,cytoplasm; kinesin complex; microtubule; microtubule motor activity,PF13374;,0,CHOYP_KLC.2.3,,,,,,,KLC_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp138555_c1_seq17,1353,42.8677,0.86391291,0,0,,3.00E-175,P37285,Kinesin light chain 1 (KLC 1),Kinesin light chain 1 (KLC 1),GO:0030424; GO:0005737; GO:0006886; GO:0005871; GO:0016020; GO:0005874; GO:0003777; GO:0043025; GO:0035418; GO:0015631; GO:0031982,axon; cytoplasm; intracellular protein transport; kinesin complex; membrane; microtubule; microtubule motor activity; neuronal cell body; protein localization to synapse; tubulin binding; vesicle,PF13374;,,,,,,,,,KLC1_RAT,Rattus norvegicus (Rat),intracellular protein transport [GO:0006886]; protein localization to synapse [GO:0035418] comp138555_c1_seq19,249,43.7751,1.52441483,0,0,,,,,,,,,,,2.00E-53,ruditapes_c16153,,,,,,, comp138555_c1_seq2,1475,42.9831,0.82846072,0,0,,0,P46825,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0005737; GO:0005871; GO:0005874; GO:0003777,cytoplasm; kinesin complex; microtubule; microtubule motor activity,PF13374;,,,,,,,,,KLC_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp138555_c1_seq5,1380,43.0435,0.83594712,0,0,,1.00E-177,Q05090,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0005737; GO:0005871; GO:0005874; GO:0003777,cytoplasm; kinesin complex; microtubule; microtubule motor activity,PF13374;,8.00E-178,CHOYP_KLC.2.3,,,,,,,KLC_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp138555_c1_seq6,894,39.5973,0.91348394,0,0,,,,,,,,,7.00E-132,CHOYP_KLC2.1.1,,,,,,,,, comp138558_c0_seq1,676,38.4615,0.56086282,46,185,,1.00E-51,Q5RA91,Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28),Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28),GO:0043923; GO:0006355; GO:0003713; GO:0005669; GO:0006367,"positive regulation by host of viral transcription; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor TFIID complex; transcription initiation from RNA polymerase II promoter",PF04719;,7.00E-42,CHOYP_AAEL_AAEL014850.1.1,,,,,,,TAF11_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp138562_c0_seq1,1749,38.3076,0.4399197,175,339,,8.00E-56,Q9D0C1,E3 ubiquitin-protein ligase RNF115 (EC 6.3.2.-) (RING finger protein 115) (Rabring 7) (Zinc finger protein 364),E3 ubiquitin-protein ligase RNF115 (EC 6.3.2.-) (RING finger protein 115) (Rabring 7) (Zinc finger protein 364),GO:0005829; GO:0051865; GO:0004842; GO:0008270,cytosol; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,2.00E-40,CHOYP_LOC100374633.1.2,,,,,,,RN115_MOUSE,Mus musculus (Mouse),negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp138563_c0_seq1,428,31.3084,0.6691213,7,0,,3.00E-10,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,5.00E-16,CHOYP_LOC100892567.8.8,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138563_c0_seq6,1208,40.2318,0.6357873,3,17,,1.00E-34,P29973,"cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)","cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)",GO:0030553; GO:0005887; GO:0005222; GO:0005223; GO:0042622; GO:0042391; GO:0022400; GO:0016056; GO:0007601; GO:0005249,cGMP binding; integral to plasma membrane; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; photoreceptor outer segment membrane; regulation of membrane potential; regulation of rhodopsin mediated signaling pathway; rhodopsin mediated signaling pathway; visual perception; voltage-gated potassium channel activity,PF16526;PF00027;PF00520;,,,,,,,,,CNGA1_HUMAN,Homo sapiens (Human),regulation of membrane potential [GO:0042391]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; rhodopsin mediated signaling pathway [GO:0016056]; transport [GO:0006810]; visual perception [GO:0007601] comp138563_c0_seq7,1226,40.6199,0.65392485,0,0,,,,,,,,,3.00E-43,CHOYP_ISCW_ISCW013674.1.1,,,,,,,,, comp138564_c1_seq1,2387,45.8316,0.59619444,56,44,,0,P81274,G-protein-signaling modulator 2 (Mosaic protein LGN),G-protein-signaling modulator 2 (Mosaic protein LGN),GO:0007186; GO:0005092; GO:0045177; GO:0005938; GO:0005737; GO:0000132; GO:0060487; GO:0005634; GO:0008277,G-protein coupled receptor signaling pathway; GDP-dissociation inhibitor activity; apical part of cell; cell cortex; cytoplasm; establishment of mitotic spindle orientation; lung epithelial cell differentiation; nucleus; regulation of G-protein coupled receptor protein signaling pathway,PF02188;PF13176;PF13181;,,,,,,,,,GPSM2_HUMAN,Homo sapiens (Human),establishment of mitotic spindle orientation [GO:0000132]; G-protein coupled receptor signaling pathway [GO:0007186]; lung epithelial cell differentiation [GO:0060487]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052] comp138564_c1_seq2,1887,46.9528,0.58593221,4,9,,8.00E-54,Q96AY4,Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0000922,cell division; cytoplasm; microtubule organizing center; midbody; mitosis; spindle pole,PF12770;PF13176;PF13181;,0,CHOYP_GPSM2.1.1,,,,,,,TTC28_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp138568_c0_seq11,2468,38.2091,0.34766756,0,0,,4.00E-116,Q6DCC6,Putative GTP-binding protein 6,Putative GTP-binding protein 6,GO:0005525,GTP binding,PF16360;PF13167;PF01926;,,,,,,,,,GTPB6_XENLA,Xenopus laevis (African clawed frog), comp138568_c0_seq12,1272,42.7673,0.29564226,0,6,,2.00E-40,Q9Z873,GTPase HflX (GTP-binding protein HflX),GTPase HflX (GTP-binding protein HflX),GO:0005525; GO:0006184; GO:0003924; GO:0005737,GTP binding; GTP catabolic process; GTPase activity; cytoplasm,PF16360;PF13167;PF01926;,,,,,,,,,HFLX_CHLPN,Chlamydia pneumoniae (Chlamydophila pneumoniae), comp138568_c0_seq5,2381,38.1352,0.32651389,0,0,,2.00E-116,Q6DCC6,Putative GTP-binding protein 6,Putative GTP-binding protein 6,GO:0005525,GTP binding,PF16360;PF13167;PF01926;,,,,,,,,,GTPB6_XENLA,Xenopus laevis (African clawed frog), comp138571_c0_seq1,1438,36.1613,0.91546256,115,610,,9.00E-43,Q5RD73,Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Vaccinia H1-related phosphatase) (VHR),Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Vaccinia H1-related phosphatase) (VHR),GO:0033549; GO:0005829; GO:0001772; GO:0070373; GO:0046329; GO:0050868; GO:0050860; GO:0005634; GO:0045931; GO:0004725; GO:0008138,MAP kinase phosphatase activity; cytosol; immunological synapse; negative regulation of ERK1 and ERK2 cascade; negative regulation of JNK cascade; negative regulation of T cell activation; negative regulation of T cell receptor signaling pathway; nucleus; positive regulation of mitotic cell cycle; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,2.00E-28,CHOYP_ISCW_ISCW009547.1.1,,,,,,,DUS3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),dephosphorylation [GO:0016311]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; positive regulation of mitotic cell cycle [GO:0045931] comp138574_c1_seq1,1417,40.7198,0.45015895,144,35,,8.00E-41,Q9LQK9,Putative isocitrate dehydrogenase [NAD] subunit-like 4 (IDH-IV) (Isocitric dehydrogenase-like protein 4) (NAD(+)-specific ICDH 4),Putative isocitrate dehydrogenase [NAD] subunit-like 4 (IDH-IV) (Isocitric dehydrogenase-like protein 4) (NAD(+)-specific ICDH 4),GO:0051287; GO:0000287; GO:0016616,"NAD binding; magnesium ion binding; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF00180;,1.00E-136,CHOYP_BRAFLDRAFT_124233.1.1,,,9.00E-116,AM864177.p.cg.6,8,male gonad,IDH4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138574_c1_seq10,1037,43.6837,0.56774549,2,76,,3.00E-55,Q96JI7,Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein),Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein),GO:0008219; GO:0031410; GO:0005829; GO:0016021; GO:0005765; GO:0005730; GO:0005886,cell death; cytoplasmic vesicle; cytosol; integral to membrane; lysosomal membrane; nucleolus; plasma membrane,PF14649;,1.00E-15,CHOYP_SPG11.1.1,,,,,,,SPTCS_HUMAN,Homo sapiens (Human),axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; synaptic vesicle transport [GO:0048489] comp138574_c1_seq2,1680,39.3452,0.42669803,21,42,,4.00E-150,Q68FX0,"Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta)","Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta)",GO:0006103; GO:0051287; GO:0006734; GO:0004449; GO:0006102; GO:0000287; GO:0005962; GO:0006099,2-oxoglutarate metabolic process; NAD binding; NADH metabolic process; isocitrate dehydrogenase (NAD+) activity; isocitrate metabolic process; magnesium ion binding; mitochondrial isocitrate dehydrogenase complex (NAD+); tricarboxylic acid cycle,PF00180;,,,,,,,,,IDH3B_RAT,Rattus norvegicus (Rat),2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; tricarboxylic acid cycle [GO:0006099] comp138574_c1_seq5,2278,36.2599,1.25606727,1402,14044,,2.00E-15,P28758,Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),GO:0001320; GO:0045454; GO:0006878; GO:0006882; GO:0005829; GO:0046872; GO:0005758; GO:0005634; GO:0019430; GO:0004784,age-dependent response to reactive oxygen species involved in chronological cell aging; cell redox homeostasis; cellular copper ion homeostasis; cellular zinc ion homeostasis; cytosol; metal ion binding; mitochondrial intermembrane space; nucleus; removal of superoxide radicals; superoxide dismutase activity,PF00080;,,,,,,,,,SODC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; removal of superoxide radicals [GO:0019430] comp138575_c0_seq14,915,47.3224,0.43506097,0,0,,,,,,,,,5.00E-45,CHOYP_BRAFLDRAFT_104092.10.11,,,,,,,,, comp138575_c0_seq17,948,49.0506,0.49803257,0,0,,,,,,,,,5.00E-45,CHOYP_BRAFLDRAFT_104092.10.11,,,,,,,,, comp138577_c0_seq1,2605,38.4645,0.60324083,270,1077,,1.00E-128,Q96RS6,NudC domain-containing protein 1 (Chronic myelogenous leukemia tumor antigen 66) (Tumor antigen CML66),NudC domain-containing protein 1 (Chronic myelogenous leukemia tumor antigen 66) (Tumor antigen CML66),GO:0005737; GO:0005634,cytoplasm; nucleus,PF04969;,,,,,,,,,NUDC1_HUMAN,Homo sapiens (Human),immune system process [GO:0002376] comp138578_c0_seq1,1103,42.7017,0.67717898,1067,81,,2.00E-147,Q5JVL4,EF-hand domain-containing protein 1 (Myoclonin-1),EF-hand domain-containing protein 1 (Myoclonin-1),GO:0005930; GO:0005509; GO:0005929; GO:0043025; GO:0008022,axoneme; calcium ion binding; cilium; neuronal cell body; protein C-terminus binding,PF06565;,0,CHOYP_BRAFLDRAFT_271463.1.1,,,3.00E-96,ES789239.p.cg.6,5,,EFHC1_HUMAN,Homo sapiens (Human),cerebral cortex cell migration [GO:0021795] comp138578_c1_seq1,1637,37.6298,0.74250502,4109,342,,,,,,,,,6.00E-15,CHOYP_LOC100377378.1.1,,,1.00E-105,CU993384.p.cg.6,5,,,, comp138582_c0_seq1,1437,43.8413,0.57072811,350,1613,,3.00E-57,Q5RDW1,Mitochondrial ribosome-associated GTPase 2 (GTP-binding protein 5),Mitochondrial ribosome-associated GTPase 2 (GTP-binding protein 5),GO:0005525; GO:0003924; GO:0000287; GO:0005743; GO:0005761; GO:0070129; GO:0044065; GO:0042254,GTP binding; GTPase activity; magnesium ion binding; mitochondrial inner membrane; mitochondrial ribosome; regulation of mitochondrial translation; regulation of respiratory system process; ribosome biogenesis,PF01018;PF01926;,8.00E-26,CHOYP_LOC100544834.1.1,,,,,,,GTPB5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),regulation of mitochondrial translation [GO:0070129]; regulation of respiratory system process [GO:0044065]; ribosome biogenesis [GO:0042254] comp138583_c0_seq1,569,26.362,0.41996814,2,0,,4.00E-12,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp138583_c0_seq2,839,28.2479,0.54902039,21,58,,1.00E-11,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp138585_c0_seq1,1927,41.7229,0.30040894,0,0,,1.00E-09,Q4L975,"Dehydrosqualene desaturase (EC 1.3.8.2) (4,4'-diapophytoene desaturase) (Diapophytoene desaturase)","Dehydrosqualene desaturase (EC 1.3.8.2) (4,4'-diapophytoene desaturase) (Diapophytoene desaturase)",GO:0016117; GO:0016491,carotenoid biosynthetic process; oxidoreductase activity,PF01593;,,,,,,,,,CRTN_STAHJ,Staphylococcus haemolyticus (strain JCSC1435),carotenoid biosynthetic process [GO:0016117] comp138585_c0_seq2,2012,41.6998,0.29931723,14,68,,,,,,,,,2.00E-98,CHOYP_PYRD2.1.1,,,,,,,,, comp138585_c0_seq3,2014,41.7577,0.30977062,0,0,,0,Q3MHH6,Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (EC 1.-.-.-),Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF01593;,,,,,,,,,PYRD2_BOVIN,Bos taurus (Bovine), comp138585_c0_seq4,1929,41.6796,0.31302252,0,32,,4.00E-20,Q52QW2,"Prolycopene isomerase 2, chloroplastic (CrtISO2) (EC 5.2.1.13) (Carotenoid isomerase 2) (OcrtISO24)","Prolycopene isomerase 2, chloroplastic (CrtISO2) (EC 5.2.1.13) (Carotenoid isomerase 2) (OcrtISO24)",GO:0016117; GO:0031969; GO:0016853,carotenoid biosynthetic process; chloroplast membrane; isomerase activity,PF01593;,,,,,,,,,CRTS2_ONCHC,Oncidium hybrid cultivar (Orchid),carotenoid biosynthetic process [GO:0016117] comp138587_c0_seq2,1073,39.795,1.10814111,208,0,,5.00E-24,P16354,Phospholipase A2 isozymes PA3A/PA3B/PA5 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase),Phospholipase A2 isozymes PA3A/PA3B/PA5 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase),GO:0005509; GO:0005576; GO:0016042; GO:0004623; GO:0006644,calcium ion binding; extracellular region; lipid catabolic process; phospholipase A2 activity; phospholipid metabolic process,PF05826;,,,,,,,,,PA23_HELSU,Heloderma suspectum (Gila monster),lipid catabolic process [GO:0016042] comp138587_c0_seq3,962,46.0499,1.144785,7,40,,2.00E-76,A8WHP3,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,,,,,,,,,SC5A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),sodium ion transport [GO:0006814] comp138587_c0_seq5,1351,43.8934,1.10867695,12,0,,4.00E-49,Q5FY69,Sodium/glucose cotransporter 5 (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10),Sodium/glucose cotransporter 5 (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10),GO:0016021; GO:0005886; GO:0006814; GO:0055085; GO:0005215,integral to membrane; plasma membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,2.00E-53,CHOYP_ISCW_ISCW012232.1.1,,,,,,,SC5AA_PIG,Sus scrofa (Pig),sodium ion transport [GO:0006814] comp138590_c1_seq1,3232,35.0248,0.56719304,3168,12229,,1.00E-93,Q9VXK6,Eukaryotic translation initiation factor 5 (eIF-5),Eukaryotic translation initiation factor 5 (eIF-5),GO:0005525; GO:0005829; GO:0022008; GO:0003743,GTP binding; cytosol; neurogenesis; translation initiation factor activity,PF01873;PF02020;,1.00E-147,CHOYP_LOC100371557.1.1,2.00E-74,ruditapes_c25625,,,,,IF5_DROME,Drosophila melanogaster (Fruit fly),neurogenesis [GO:0022008]; translational initiation [GO:0006413] comp138595_c0_seq1,2199,41.0186,1.05293304,200,14,,2.00E-43,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp138595_c0_seq2,630,43.0159,1.0385148,0,0,,,,,,,,,4.00E-13,CHOYP_LOC100378512.5.6,,,,,,,,, comp138596_c1_seq1,1661,39.4341,1.06991754,20,336,,1.00E-15,Q1RNF8,Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s),Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s),GO:0042731; GO:0032093; GO:0000122; GO:0005634; GO:0043621,PH domain binding; SAM domain binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein self-association,PF00536;,,,,,,,,,SAM11_MOUSE,Mus musculus (Mouse),negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp138600_c1_seq4,342,36.5497,0.18177156,3,7,,3.00E-08,Q8QG61,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0005737; GO:0000166; GO:0005634; GO:0009881; GO:0018298; GO:0006355; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; cytoplasm; nucleotide binding; nucleus; photoreceptor activity; protein-chromophore linkage; regulation of transcription, DNA-dependent; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY1_CHICK,Gallus gallus (Chicken),"protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp138601_c0_seq2,1135,41.2335,0.89741398,0,0,,7.00E-06,P02207,Globin,Globin,GO:0020037; GO:0005506; GO:0019825; GO:0005344,heme binding; iron ion binding; oxygen binding; oxygen transporter activity,PF00042;,,,,,,,,,GLB_LAMFL,Lampetra fluviatilis (European river lamprey) (Petromyzon fluviatilis), comp138601_c0_seq3,980,41.3265,0.98663204,0,0,,2.00E-18,P41261,Hemoglobin-2 (Hemoglobin II) (Hb II) (HbII),Hemoglobin-2 (Hemoglobin II) (Hb II) (HbII),GO:0005737; GO:0020037; GO:0005506; GO:0019825; GO:0005344,cytoplasm; heme binding; iron ion binding; oxygen binding; oxygen transporter activity,PF00042;,,,,,,,,,GLB2_PHAPT,Phacoides pectinatus (Thick lucine) (Lucina pectinata), comp138601_c0_seq4,1160,40.7759,0.89805787,0,32,,3.00E-17,P41262,Hemoglobin-3 (Hemoglobin III) (Hb III),Hemoglobin-3 (Hemoglobin III) (Hb III),GO:0005737; GO:0020037; GO:0005506; GO:0019825; GO:0005344,cytoplasm; heme binding; iron ion binding; oxygen binding; oxygen transporter activity,PF00042;,,,,,,,,,GLB3_PHAPT,Phacoides pectinatus (Thick lucine) (Lucina pectinata), comp138604_c0_seq3,2777,45.3367,0.36468294,8,0,,0,Q32N90,MBT domain-containing protein 1,MBT domain-containing protein 1,GO:0016568; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF02820;,0,CHOYP_SMBT.1.1,,,,,,,MBTD1_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138604_c0_seq4,2777,45.3367,0.3645909,0,0,,0,Q32N90,MBT domain-containing protein 1,MBT domain-containing protein 1,GO:0016568; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF02820;,,,,,,,,,MBTD1_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138607_c0_seq1,1535,33.2248,0.66402165,16,46,,3.00E-17,B6LI37,UPF0722 protein,UPF0722 protein,,,,,,,,,,,,U722_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),skeletal muscle fiber development [GO:0048741] comp138607_c0_seq3,1500,33.6,0.64044972,0,12,,3.00E-17,B6LI37,UPF0722 protein,UPF0722 protein,,,,,,,,,,,,U722_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),skeletal muscle fiber development [GO:0048741] comp138608_c0_seq2,519,42.7746,0.43218246,33,193,,2.00E-83,Q6DFI2,Transmembrane protein 147,Transmembrane protein 147,GO:0016021,integral to membrane,PF09767;,2.00E-105,CHOYP_LOC100370503.1.1,,,,,,,TM147_XENLA,Xenopus laevis (African clawed frog), comp138616_c0_seq1,2427,42.2744,0.56676881,910,5126,,0,P23687,Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme),Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme),GO:0005737; GO:0006508; GO:0004252; GO:0070008,cytoplasm; proteolysis; serine-type endopeptidase activity; serine-type exopeptidase activity,PF00326;PF02897;,0,CHOYP_BRAFLDRAFT_204923.1.2,,,,,,,PPCE_PIG,Sus scrofa (Pig),proteolysis [GO:0006508] comp138618_c0_seq1,2539,40.449,0.52145755,0,0,,0,P17625,"Glycogen [starch] synthase, liver (EC 2.4.1.11)","Glycogen [starch] synthase, liver (EC 2.4.1.11)",GO:0030864; GO:0005829; GO:0043265; GO:0005536; GO:0004373; GO:0005978; GO:0009749,cortical actin cytoskeleton; cytosol; ectoplasm; glucose binding; glycogen (starch) synthase activity; glycogen biosynthetic process; response to glucose stimulus,PF05693;,4.00E-96,CHOYP_LOC100368259.1.1,,,,,,,GYS2_RAT,Rattus norvegicus (Rat),glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; response to glucose [GO:0009749] comp138618_c0_seq13,1681,44.3189,0.47464634,0,0,,,,,,,,,8.00E-103,CHOYP_LOC100368259.1.1,,,,,,,,, comp138618_c0_seq14,1495,44.8829,0.45450829,0,0,,1.00E-163,Q8VCB3,"Glycogen [starch] synthase, liver (EC 2.4.1.11)","Glycogen [starch] synthase, liver (EC 2.4.1.11)",GO:0030864; GO:0005829; GO:0043265; GO:0004373; GO:0005978; GO:0009749,cortical actin cytoskeleton; cytosol; ectoplasm; glycogen (starch) synthase activity; glycogen biosynthetic process; response to glucose stimulus,PF05693;,,,,,,,,,GYS2_MOUSE,Mus musculus (Mouse),glycogen biosynthetic process [GO:0005978]; response to glucose [GO:0009749] comp138618_c0_seq2,2710,40.1845,0.48577994,0,0,,0,Q9VFC8,Putative glycogen [starch] synthase (EC 2.4.1.11),Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase),GO:0004373; GO:0005978,glycogen (starch) synthase activity; glycogen biosynthetic process,PF05693;,,,,,,,,,GYS_DROME,Drosophila melanogaster (Fruit fly),cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744] comp138618_c0_seq8,1390,43.8849,0.41933248,0,0,,,,,,,,,4.00E-92,CHOYP_LOC100368259.1.1,,,,,,,,, comp138618_c0_seq9,1666,44.2377,0.45623278,0,0,,0,Q9VFC8,Putative glycogen [starch] synthase (EC 2.4.1.11),Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase),GO:0004373; GO:0005978,glycogen (starch) synthase activity; glycogen biosynthetic process,PF05693;,,,,,,,,,GYS_DROME,Drosophila melanogaster (Fruit fly),cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744] comp138622_c0_seq1,1302,37.788,0.53996406,7,0,,1.00E-08,Q1HAQ0,Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2),Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2),GO:0047184; GO:0047192; GO:0005794; GO:0000139; GO:0005509; GO:0005783; GO:0005789; GO:0016021; GO:0005811; GO:2001246; GO:0008654; GO:0045732; GO:0060041; GO:0043129,1-acylglycerophosphocholine O-acyltransferase activity; 1-alkylglycerophosphocholine O-acetyltransferase activity; Golgi apparatus; Golgi membrane; calcium ion binding; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; lipid particle; negative regulation of phosphatidylcholine biosynthetic process; phospholipid biosynthetic process; positive regulation of protein catabolic process; retina development in camera-type eye; surfactant homeostasis,PF01553;PF13833;,6.00E-71,CHOYP_GPAT4.1.1,,,,,,,PCAT1_RAT,Rattus norvegicus (Rat),negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phospholipid biosynthetic process [GO:0008654]; positive regulation of protein catabolic process [GO:0045732]; retina development in camera-type eye [GO:0060041]; surfactant homeostasis [GO:0043129] comp138622_c0_seq2,1976,39.2206,0.63021138,28,32,,2.00E-154,Q8K2C8,Glycerol-3-phosphate acyltransferase 4 (GPAT4) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta),Glycerol-3-phosphate acyltransferase 4 (GPAT4) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta),GO:0016024; GO:0006637; GO:0046339; GO:0006631; GO:0002071; GO:0004366; GO:0030176; GO:0007595; GO:0006656; GO:0040014; GO:0019432,CDP-diacylglycerol biosynthetic process; acyl-CoA metabolic process; diacylglycerol metabolic process; fatty acid metabolic process; glandular epithelial cell maturation; glycerol-3-phosphate O-acyltransferase activity; integral to endoplasmic reticulum membrane; lactation; phosphatidylcholine biosynthetic process; regulation of multicellular organism growth; triglyceride biosynthetic process,PF01553;,,,,,,,,,GPAT4_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; diacylglycerol metabolic process [GO:0046339]; fatty acid metabolic process [GO:0006631]; glandular epithelial cell maturation [GO:0002071]; lactation [GO:0007595]; lipid biosynthetic process [GO:0008610]; mammary gland development [GO:0030879]; phosphatidylcholine biosynthetic process [GO:0006656]; regulation of multicellular organism growth [GO:0040014]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641] comp138625_c0_seq2,1075,41.7674,0.89720149,0,0,,3.00E-09,Q9GPR3,TM2 domain-containing protein DDB_G0277895,TM2 domain-containing protein DDB_G0277895,GO:0016021,integral to membrane,PF05154;,,,,,,,,,TM2D1_DICDI,Dictyostelium discoideum (Slime mold), comp138626_c1_seq2,1695,45.7817,0.49602527,164,428,,0,Q8AVG9,"Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.-) (Glutaminyl-tRNA synthase-like protein 1)","Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Glutaminyl-tRNA synthase-like protein 1)",GO:0005524; GO:0016884; GO:0005739; GO:0006412,"ATP binding; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; mitochondrion; translation",PF01425;,,,,,,,,,GATA_XENLA,Xenopus laevis (African clawed frog),glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543] comp138626_c1_seq3,745,44.9664,0.56203014,0,0,,1.00E-94,F1QAJ4,"Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.-) (Glutaminyl-tRNA synthase-like protein 1)","Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Glutaminyl-tRNA synthase-like protein 1)",GO:0005524; GO:0016884; GO:0005739; GO:0006412,"ATP binding; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; mitochondrion; translation",PF01425;,4.00E-64,CHOYP_LOC583954.1.1,,,,,,,GATA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543] comp138629_c1_seq1,1410,42.9787,0.38729708,95,475,,3.00E-125,Q5ZM96,Queuine tRNA-ribosyltransferase subunit QTRTD1 (EC 2.4.2.29) (Queuine tRNA-ribosyltransferase domain-containing protein 1),Queuine tRNA-ribosyltransferase subunit QTRTD1 (EC 2.4.2.29) (Queuine tRNA-ribosyltransferase domain-containing protein 1),GO:0046872; GO:0005739; GO:0008479; GO:0008616,metal ion binding; mitochondrion; queuine tRNA-ribosyltransferase activity; queuosine biosynthetic process,PF01702;,8.00E-13,CHOYP_QTRTD1.1.1,7.00E-37,ruditapes_c11116,,,,,QTRD1_CHICK,Gallus gallus (Chicken),queuosine biosynthetic process [GO:0008616]; tRNA modification [GO:0006400] comp138631_c0_seq1,1769,42.8491,0.46983397,66,114,,4.00E-50,Q49LS8,XK-related protein 6,XK-related protein 6,GO:0016021,integral to membrane,PF09815;,1.00E-12,CHOYP_PHUM_PHUM225050.1.1,,,,,,,XKR6_TETNG,Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis), comp138632_c0_seq1,1739,40.8281,0.9247452,126,200,,7.00E-11,Q568Y5,Tetraspanin-11 (Tspan-11),Tetraspanin-11 (Tspan-11),GO:0016021,integral to membrane,PF00335;,1.00E-17,CHOYP_DSEC_GM10209.1.1,,,,,,,TSN11_RAT,Rattus norvegicus (Rat),cell surface receptor signaling pathway [GO:0007166] comp138634_c1_seq1,531,46.3277,0.4312072,38,47,,1.00E-12,Q91ZU6,Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0016023; GO:0031122; GO:0005789; GO:0005925; GO:0030056; GO:0016021; GO:0014704; GO:0005882; GO:0045104; GO:0009898; GO:0046907; GO:0015630; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0097038; GO:0042803; GO:0031110; GO:0008090; GO:0042383; GO:0001725,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; endoplasmic reticulum membrane; focal adhesion; hemidesmosome; integral to membrane; intercalated disc; intermediate filament; intermediate filament cytoskeleton organization; internal side of plasma membrane; intracellular transport; microtubule cytoskeleton; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; retrograde axon cargo transport; sarcolemma; stress fiber,PF00307;PF13499;PF02187;PF00681;PF00435;,,,,,,,,,DYST_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090] comp138634_c2_seq2,1612,46.2779,0.52188,4,0,,2.00E-68,P11533,Dystrophin,Dystrophin,GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0045211; GO:0042383; GO:0008270,calcium ion binding; cell junction; cytoplasm; cytoskeleton; postsynaptic membrane; sarcolemma; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;,1.00E-24,CHOYP_DLP.1.1,,,,,,,DMD_CHICK,Gallus gallus (Chicken),muscle attachment [GO:0016203] comp138634_c4_seq1,705,46.8085,0.47120863,0,0,,2.00E-07,Q91ZU6,Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0016023; GO:0031122; GO:0005789; GO:0005925; GO:0030056; GO:0016021; GO:0014704; GO:0005882; GO:0045104; GO:0009898; GO:0046907; GO:0015630; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0097038; GO:0042803; GO:0031110; GO:0008090; GO:0042383; GO:0001725,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; endoplasmic reticulum membrane; focal adhesion; hemidesmosome; integral to membrane; intercalated disc; intermediate filament; intermediate filament cytoskeleton organization; internal side of plasma membrane; intracellular transport; microtubule cytoskeleton; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; retrograde axon cargo transport; sarcolemma; stress fiber,PF00307;PF13499;PF02187;PF00681;PF00435;,,,,,,,,,DYST_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090] comp138634_c4_seq4,693,47.0418,0.47418866,0,0,,1.00E-33,O97592,Dystrophin,Dystrophin,GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0045211; GO:0042383; GO:0008270,calcium ion binding; cell junction; cytoplasm; cytoskeleton; postsynaptic membrane; sarcolemma; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;,,,,,,,,,DMD_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),muscle attachment [GO:0016203] comp138640_c0_seq3,891,32.9966,0.37261593,72,249,,,,,,,,,,,6.00E-16,ruditapes2_lrc4297,,,,,,, comp138642_c0_seq4,2809,38.6614,0.28612744,35,109,,1.00E-14,P10072,Krueppel-related zinc finger protein 1 (Protein HKR1) (Zinc finger protein 875),Krueppel-related zinc finger protein 1 (Protein HKR1) (Zinc finger protein 875),GO:0003677; GO:0007275; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,HKR1_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138644_c0_seq1,369,43.0894,0.41020257,10,6,,1.00E-08,Q8WPD0,Alpha-N-acetylgalactosamine-specific lectin (Alpha-N-acetylgalactosamine-binding lectin) (GalNAc-specific lectin) (Lectin) (ApL) (Tn antigen-specific lectin),Alpha-N-acetylgalactosamine-specific lectin (Alpha-N-acetylgalactosamine-binding lectin) (GalNAc-specific lectin) (Lectin) (ApL) (Tn antigen-specific lectin),GO:0030246,carbohydrate binding,PF00059;,,,,,,,,,LECG_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera), comp138644_c1_seq2,1932,41.2008,0.40300612,47,46,,9.00E-25,Q61830,Macrophage mannose receptor 1 (MMR) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (CD antigen CD206),GO:0009986; GO:0010008; GO:0016021; GO:0005537; GO:0005886; GO:0006898; GO:0004888,cell surface; endosome membrane; integral to membrane; mannose binding; plasma membrane; receptor-mediated endocytosis; transmembrane signaling receptor activity,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp138644_c1_seq4,383,44.6475,0.42059432,11,14,,4.00E-13,Q61830,Macrophage mannose receptor 1 (MMR) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (CD antigen CD206),GO:0009986; GO:0010008; GO:0016021; GO:0005537; GO:0005886; GO:0006898; GO:0004888,cell surface; endosome membrane; integral to membrane; mannose binding; plasma membrane; receptor-mediated endocytosis; transmembrane signaling receptor activity,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp138648_c0_seq1,942,28.7686,0.10275701,15,204,,,,,,,,,,,5.00E-11,ruditapes_c3364,,,,,,, comp138648_c3_seq1,1122,46.2567,1.06777681,33,87,,2.00E-41,O88575,Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B),Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B),GO:0016324; GO:0005887; GO:0005328; GO:0005215,apical plasma membrane; integral to plasma membrane; neurotransmitter:sodium symporter activity; transporter activity,PF00209;,3.00E-74,CHOYP_S6A11.1.1,,,,,,,S620B_MOUSE,Mus musculus (Mouse),"glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp138648_c3_seq3,427,42.1546,1.16376859,1,23,,,,,,,,,,,3.00E-22,ruditapes2_c2910,,,,,,, comp138648_c4_seq1,1333,42.5356,0.79800643,118,497,,1.00E-128,Q9MZ34,Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6),Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6),GO:0005887; GO:0005328; GO:0005369,integral to plasma membrane; neurotransmitter:sodium symporter activity; taurine:sodium symporter activity,PF00209;,8.00E-114,CHOYP_LOC100533491.1.1,5.00E-26,ruditapes_c8804,,,,,SC6A6_BOVIN,Bos taurus (Bovine),amino acid transmembrane transport [GO:0003333]; taurine transport [GO:0015734] comp138653_c0_seq1,2934,32.9925,0.72720834,4602,25737,,4.00E-27,P55814,Ornithine decarboxylase antizyme 1 (ODC-Az),Ornithine decarboxylase antizyme 1 (ODC-Az),GO:0043086; GO:0008073,negative regulation of catalytic activity; ornithine decarboxylase inhibitor activity,PF02100;,2.00E-50,CHOYP_OAZ1.1.2,4.00E-138,ruditapes_c4622,,,,,OAZ1_XENLA,Xenopus laevis (African clawed frog),polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316] comp138653_c0_seq2,1596,40.2256,0.7750549,299,2223,,8.00E-24,Q9YI97,"Ornithine decarboxylase antizyme 2 (ODC antizyme, long form) (ODC-Az-L)","Ornithine decarboxylase antizyme 2 (ODC antizyme, long form) (ODC-Az-L)",GO:0043086; GO:0008073,negative regulation of catalytic activity; ornithine decarboxylase inhibitor activity,PF02100;,1.00E-54,CHOYP_LOC100376797.1.1,2.00E-81,ruditapes_c3716,,,,,OAZ2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316] comp138654_c1_seq3,995,43.8191,0.50816378,12,54,,1.00E-83,Q9NZJ6,"Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial (EC 2.1.1.114) (2-polyprenyl-6-hydroxyphenol methylase) (EC 2.1.1.222) (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase) (3-demethylubiquinone-10 3-methyltransferase) (EC 2.1.1.64) (Dihydroxyhexaprenylbenzoate methyltransferase)","Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114)",GO:0008425; GO:0008689; GO:0008171; GO:0006071; GO:0004395; GO:0005759; GO:0006744,"2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; 3-demethylubiquinone-9 3-O-methyltransferase activity; O-methyltransferase activity; glycerol metabolic process; hexaprenyldihydroxybenzoate methyltransferase activity; mitochondrial matrix; ubiquinone biosynthetic process",,8.00E-18,CHOYP_LOC101068003.1.1,,,,,,,COQ3_HUMAN,Homo sapiens (Human),glycerol metabolic process [GO:0006071]; ubiquinone biosynthetic process [GO:0006744] comp138654_c1_seq4,995,43.7186,0.51076975,0,0,,6.00E-55,B0UAV0,Ubiquinone biosynthesis O-methyltransferase (2-polyprenyl-6-hydroxyphenol methylase) (EC 2.1.1.222) (3-demethylubiquinone 3-O-methyltransferase) (EC 2.1.1.64),Ubiquinone biosynthesis O-methyltransferase (2-polyprenyl-6-hydroxyphenol methylase) (EC 2.1.1.222) (3-demethylubiquinone 3-O-methyltransferase) (EC 2.1.1.64),GO:0008425; GO:0008689; GO:0006744,"2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; 3-demethylubiquinone-9 3-O-methyltransferase activity; ubiquinone biosynthetic process",PF08241;,8.00E-18,CHOYP_LOC101068003.1.1,,,,,,,UBIG_METS4,Methylobacterium sp. (strain 4-46),ubiquinone biosynthetic process [GO:0006744] comp138655_c1_seq1,1796,34.8552,0.53411448,20,0,,3.00E-21,Q5T619,Zinc finger protein 648,Zinc finger protein 648,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,2.00E-73,CHOYP_LOC100678227.1.1,,,,,,,ZN648_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138655_c1_seq2,1886,36.7444,0.5208523,0,11,,2.00E-15,P08970,Protein suppressor of hairy wing,Protein suppressor of hairy wing,GO:0000785; GO:0043035; GO:0016568; GO:0046872; GO:0031936; GO:0045892; GO:0005634; GO:0005700; GO:0043565; GO:0006351,"chromatin; chromatin insulator sequence binding; chromatin modification; metal ion binding; negative regulation of chromatin silencing; negative regulation of transcription, DNA-dependent; nucleus; polytene chromosome; sequence-specific DNA binding; transcription, DNA-dependent",PF13912;,,,,,,,,,SUHW_DROME,Drosophila melanogaster (Fruit fly),"chromatin modification [GO:0016568]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp138655_c1_seq3,1880,37.234,0.4957707,0,0,,8.00E-17,Q9HCG1,Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18),Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18),GO:0003677; GO:0030097; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; hemopoiesis; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,2.00E-73,CHOYP_LOC100678227.1.1,,,,,,,ZN160_HUMAN,Homo sapiens (Human),"hemopoiesis [GO:0030097]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138656_c0_seq1,2421,38.0834,0.45881648,794,5148,,0,O75844,CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog),CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog),GO:0071586; GO:0005789; GO:0016021; GO:0046872; GO:0004222; GO:0008235; GO:0006998; GO:0005637; GO:0030327; GO:0006508,CAAX-box protein processing; endoplasmic reticulum membrane; integral to membrane; metal ion binding; metalloendopeptidase activity; metalloexopeptidase activity; nuclear envelope organization; nuclear inner membrane; prenylated protein catabolic process; proteolysis,PF01435;PF16491;,4.00E-89,CHOYP_FACE1.1.1,,,,,,,FACE1_HUMAN,Homo sapiens (Human),CAAX-box protein processing [GO:0071586]; nuclear envelope organization [GO:0006998]; prenylated protein catabolic process [GO:0030327]; proteolysis [GO:0006508] comp138657_c0_seq2,1350,39.1111,0.48485528,0,4,,4.00E-13,Q54NU5,BTG family protein,BTG family protein,GO:0045165,cell fate commitment,PF07742;,7.00E-26,CHOYP_EF1A2.2.3,,,,,,,BTG_DICDI,Dictyostelium discoideum (Slime mold),cell fate commitment [GO:0045165] comp138657_c0_seq6,1606,37.1108,0.54318088,19,61,,1.00E-35,P40744,Maternal B9.10 protein (p30 B9.10),Maternal B9.10 protein (p30 B9.10),,,PF07742;,,,,,,,,,B910_XENLA,Xenopus laevis (African clawed frog),negative regulation of cell proliferation [GO:0008285] comp138658_c0_seq5,697,30.1291,0.44576317,440,514,,,,,,,,,,,1.00E-11,ruditapes_c8275,,,,,,, comp138658_c0_seq6,2052,39.3275,0.34096285,71,133,,6.00E-15,Q3UK37,Uncharacterized protein C14orf80 homolog,Uncharacterized protein C14orf80 homolog,,,PF14970;PF14971;,3.00E-32,CHOYP_LOC100717056.1.1,,,,,,,CN080_MOUSE,Mus musculus (Mouse), comp138662_c0_seq14,2532,45.9321,0.51295163,0,0,,4.00E-97,Q24247,Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain],Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain],GO:0007015; GO:0016324; GO:0007475; GO:0007411; GO:0007414; GO:0007155; GO:0050839; GO:0007160; GO:0048567; GO:0007427; GO:0007157; GO:0008305; GO:0007229; GO:0016328; GO:0035160; GO:0007494; GO:0016203; GO:0004872; GO:0007432; GO:0007435; GO:0007608; GO:0007426,"actin filament organization; apical plasma membrane; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; axonal defasciculation; cell adhesion; cell adhesion molecule binding; cell-matrix adhesion; ectodermal digestive tract morphogenesis; epithelial cell migration, open tracheal system; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; midgut development; muscle attachment; receptor activity; salivary gland boundary specification; salivary gland morphogenesis; sensory perception of smell; tracheal outgrowth, open tracheal system",PF01839;PF08441;,,,,,,,,,ITA1_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ectodermal digestive tract morphogenesis [GO:0048567]; epithelial cell migration, open tracheal system [GO:0007427]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; open tracheal system development [GO:0007424]; salivary gland boundary specification [GO:0007432]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]" comp138662_c0_seq18,748,35.4278,0.55595623,0,0,,,,,,,,,,,2.00E-41,ruditapes2_c3684,,,,,,, comp138662_c0_seq2,2970,45.4882,0.55165194,0,0,,5.00E-120,Q24247,Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain],Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain],GO:0007015; GO:0016324; GO:0007475; GO:0007411; GO:0007414; GO:0007155; GO:0050839; GO:0007160; GO:0048567; GO:0007427; GO:0007157; GO:0008305; GO:0007229; GO:0016328; GO:0035160; GO:0007494; GO:0016203; GO:0004872; GO:0007432; GO:0007435; GO:0007608; GO:0007426,"actin filament organization; apical plasma membrane; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; axonal defasciculation; cell adhesion; cell adhesion molecule binding; cell-matrix adhesion; ectodermal digestive tract morphogenesis; epithelial cell migration, open tracheal system; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; midgut development; muscle attachment; receptor activity; salivary gland boundary specification; salivary gland morphogenesis; sensory perception of smell; tracheal outgrowth, open tracheal system",PF01839;PF08441;,,,,,,,,,ITA1_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ectodermal digestive tract morphogenesis [GO:0048567]; epithelial cell migration, open tracheal system [GO:0007427]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; open tracheal system development [GO:0007424]; salivary gland boundary specification [GO:0007432]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]" comp138662_c0_seq24,1014,45.6607,0.5788979,0,0,,5.00E-11,P80108,Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),GO:0006507; GO:0002042; GO:0071277; GO:0071397; GO:0035690; GO:0071467; GO:0071401; GO:0002062; GO:0002430; GO:0005615; GO:0004621; GO:0097241; GO:0008286; GO:0005765; GO:0008285; GO:0010897; GO:0001503; GO:0046470; GO:0010694; GO:0043065; GO:0045919; GO:0010595; GO:0010907; GO:0010983; GO:0035774; GO:0051044; GO:0010867; GO:0005578; GO:1900076; GO:0009749; GO:0017080; GO:0070633,GPI anchor release; cell migration involved in sprouting angiogenesis; cellular response to calcium ion; cellular response to cholesterol; cellular response to drug; cellular response to pH; cellular response to triglyceride; chondrocyte differentiation; complement receptor mediated signaling pathway; extracellular space; glycosylphosphatidylinositol phospholipase D activity; hematopoietic stem cell migration to bone marrow; insulin receptor signaling pathway; lysosomal membrane; negative regulation of cell proliferation; negative regulation of triglyceride catabolic process; ossification; phosphatidylcholine metabolic process; positive regulation of alkaline phosphatase activity; positive regulation of apoptotic process; positive regulation of cytolysis; positive regulation of endothelial cell migration; positive regulation of glucose metabolic process; positive regulation of high-density lipoprotein particle clearance; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of membrane protein ectodomain proteolysis; positive regulation of triglyceride biosynthetic process; proteinaceous extracellular matrix; regulation of cellular response to insulin stimulus; response to glucose stimulus; sodium channel regulator activity; transepithelial transport,PF01839;PF00882;,,,,,,,,,PHLD_HUMAN,Homo sapiens (Human),cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633] comp138662_c0_seq26,1319,46.5504,0.49865651,0,0,,1.00E-40,P53708,Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain],Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain],GO:0034678; GO:0045177; GO:0030030; GO:0016337; GO:0007160; GO:0045184; GO:0030198; GO:0042472; GO:0007229; GO:0007613; GO:0046872; GO:0001656; GO:0007399; GO:2000721; GO:0030511; GO:0048745,alpha8-beta1 integrin complex; apical part of cell; cell projection organization; cell-cell adhesion; cell-matrix adhesion; establishment of protein localization; extracellular matrix organization; inner ear morphogenesis; integrin-mediated signaling pathway; memory; metal ion binding; metanephros development; nervous system development; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; positive regulation of transforming growth factor beta receptor signaling pathway; smooth muscle tissue development,PF01839;PF00357;PF08441;,,,,,,,,,ITA8_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; metanephros development [GO:0001656]; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation [GO:2000721]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; single organismal cell-cell adhesion [GO:0016337]; smooth muscle tissue development [GO:0048745]; substrate adhesion-dependent cell spreading [GO:0034446] comp138662_c0_seq28,2227,45.4423,0.55166733,0,0,,2.00E-76,Q24247,Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain],Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain],GO:0007015; GO:0016324; GO:0007475; GO:0007411; GO:0007414; GO:0007155; GO:0050839; GO:0007160; GO:0048567; GO:0007427; GO:0007157; GO:0008305; GO:0007229; GO:0016328; GO:0035160; GO:0007494; GO:0016203; GO:0004872; GO:0007432; GO:0007435; GO:0007608; GO:0007426,"actin filament organization; apical plasma membrane; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; axonal defasciculation; cell adhesion; cell adhesion molecule binding; cell-matrix adhesion; ectodermal digestive tract morphogenesis; epithelial cell migration, open tracheal system; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; midgut development; muscle attachment; receptor activity; salivary gland boundary specification; salivary gland morphogenesis; sensory perception of smell; tracheal outgrowth, open tracheal system",PF01839;PF08441;,,,,,,,,,ITA1_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ectodermal digestive tract morphogenesis [GO:0048567]; epithelial cell migration, open tracheal system [GO:0007427]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; open tracheal system development [GO:0007424]; salivary gland boundary specification [GO:0007432]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]" comp138662_c0_seq4,1757,45.646,0.5678692,0,0,,2.00E-40,Q9W1M8,Integrin alpha-PS5 (Position-specific antigen subunit alpha-5),Integrin alpha-PS5 (Position-specific antigen subunit alpha-5),GO:0050839; GO:0007160; GO:0007157; GO:0008305; GO:0007229; GO:0001555; GO:0004872,cell adhesion molecule binding; cell-matrix adhesion; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; oocyte growth; receptor activity,PF08441;,,,,,,,,,ITA5_DROME,Drosophila melanogaster (Fruit fly),cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; integrin-mediated signaling pathway [GO:0007229]; oocyte growth [GO:0001555] comp138662_c0_seq8,1662,45.2467,0.51889534,0,0,,3.00E-25,P53711,Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain] (Fragment),Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain] (Fragment),GO:0007155; GO:0008305; GO:0007229; GO:0046872; GO:0005886; GO:0031092,cell adhesion; integrin complex; integrin-mediated signaling pathway; metal ion binding; plasma membrane; platelet alpha granule membrane,PF00357;PF08441;,,,,,,,,,ITA2B_PAPCY,Papio cynocephalus (Yellow baboon),cell adhesion [GO:0007155]; integrin-mediated signaling pathway [GO:0007229] comp138664_c0_seq1,1246,44.5425,0.90931878,208,1788,,2.00E-98,Q5EA79,Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase),Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase),GO:0004034; GO:0030246; GO:0005737; GO:0019318,aldose 1-epimerase activity; carbohydrate binding; cytoplasm; hexose metabolic process,PF01263;,,,,,,,,,GALM_BOVIN,Bos taurus (Bovine),galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006] comp138665_c0_seq2,2030,30.9852,0.67823332,1,29,,2.00E-09,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138665_c0_seq3,2162,30.8973,0.65924446,0,0,,2.00E-09,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,2.00E-15,CHOYP_LOC764672.1.1,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp138665_c0_seq4,2185,30.8467,0.67371123,0,0,,,,,,,,,9.00E-15,CHOYP_LOC764672.1.1,,,,,,,,, comp138666_c0_seq1,2346,34.399,0.58086162,2206,6955,,1.00E-46,C4A0P0,CDGSH iron-sulfur domain-containing protein 2 homolog B,CDGSH iron-sulfur domain-containing protein 2 homolog B,GO:0051537; GO:0005789; GO:0016021; GO:0046872,"2 iron, 2 sulfur cluster binding; endoplasmic reticulum membrane; integral to membrane; metal ion binding",PF10660;PF09360;,8.00E-35,CHOYP_CID2A.1.1,2.00E-66,ruditapes_c12791,,,,,CID2B_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus), comp138668_c0_seq1,1742,37.3134,0.43202806,414,3329,,2.00E-154,Q90511,Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta),Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta),GO:0005524; GO:0005525; GO:0051716; GO:0005851; GO:0005085; GO:0042552; GO:0014003; GO:0006446; GO:0003743; GO:0006413,ATP binding; GTP binding; cellular response to stimulus; eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor activity; myelination; oligodendrocyte development; regulation of translational initiation; translation initiation factor activity; translational initiation,PF01008;,2.00E-155,CHOYP_LOC100367093.1.1,,,,,,,EI2BB_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),cellular response to stimulus [GO:0051716]; central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp138669_c0_seq1,718,40.6685,0.78646655,2,26,,3.00E-51,P36639,"7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1)","7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1)",GO:0035539; GO:0008413; GO:0006200; GO:0047693; GO:0042262; GO:0006281; GO:0003924; GO:0005829; GO:0006203; GO:0046872; GO:0005759; GO:0034656; GO:0005634; GO:0006979; GO:0030515,"8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; ATP catabolic process; ATP diphosphatase activity; DNA protection; DNA repair; GTPase activity; cytosol; dGTP catabolic process; metal ion binding; mitochondrial matrix; nucleobase-containing small molecule catabolic process; nucleus; response to oxidative stress; snoRNA binding",PF00293;,8.00E-16,CHOYP_LOC587752.1.1,,,,,,,8ODP_HUMAN,Homo sapiens (Human),dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to oxidative stress [GO:0006979] comp138673_c0_seq1,1808,45.7965,1.17888599,131,736,,2.00E-46,Q2PC93,SCO-spondin,SCO-spondin,GO:0007155; GO:0005615,cell adhesion; extracellular space,PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;,,,,,,,,,SSPO_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp138673_c0_seq2,568,42.6056,1.05392383,10,64,,1.00E-25,O75581,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0034185; GO:0090245; GO:0060349; GO:0046849; GO:0060444; GO:0061310; GO:0044335; GO:0061324; GO:0044340; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0021987; GO:0060026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0030326; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:0005886; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0045598; GO:0030278; GO:0051593; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; apolipoprotein binding; axis elongation involved in somitogenesis; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; canonical Wnt receptor signaling pathway involved in regulation of cell proliferation; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; cerebral cortex development; convergent extension; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic limb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; plasma membrane; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; regulation of fat cell differentiation; regulation of ossification; response to folic acid; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,,,,,,,,,LRP6_HUMAN,Homo sapiens (Human),"axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; single organismal cell-cell adhesion [GO:0016337]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp138679_c0_seq1,1086,41.989,0.60681887,162,918,,2.00E-66,Q5R7P7,Transcription initiation factor TFIID subunit 9B,Transcription initiation factor TFIID subunit 9B,GO:0003677; GO:0006352; GO:0043066; GO:0000122; GO:0030307; GO:0050821; GO:0005669; GO:0033276,"DNA binding; DNA-dependent transcription, initiation; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell growth; protein stabilization; transcription factor TFIID complex; transcription factor TFTC complex",PF02291;,1.00E-47,CHOYP_LOC100538996.1.1,2.00E-79,ruditapes_c13945,,,,,TAF9B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]" comp138683_c0_seq1,1883,35.4753,0.45815896,644,5329,,5.00E-101,A4QND5,60S ribosome subunit biogenesis protein NIP7 homolog,60S ribosome subunit biogenesis protein NIP7 homolog,GO:0003723; GO:0005730; GO:0042255,RNA binding; nucleolus; ribosome assembly,PF03657;,3.00E-96,CHOYP_LOC100368820.1.1,,,,,,,NIP7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ribosomal large subunit biogenesis [GO:0042273]; ribosome assembly [GO:0042255] comp138685_c0_seq1,1757,33.9215,0.41779944,202,752,,,,,,,,,2.00E-14,CHOYP_DHSD.1.1,,,,,,,,, comp138685_c0_seq2,1778,33.802,0.41584866,44,173,,3.00E-21,Q6AZV0,"Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial (CybS-B) (Succinate dehydrogenase complex subunit D-B) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit B) (Succinate-ubiquinone reductase membrane anchor subunit B)","Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial (CybS-B) (Succinate dehydrogenase complex subunit D-B) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit B) (Succinate-ubiquinone reductase membrane anchor subunit B)",GO:0020037; GO:0016021; GO:0046872; GO:0005749; GO:0006099; GO:0048039,heme binding; integral to membrane; metal ion binding; mitochondrial respiratory chain complex II; tricarboxylic acid cycle; ubiquinone binding,,2.00E-16,CHOYP_CRE-DIG-1.1.1,2.00E-71,ruditapes_c7902,,,,,DHSDB_XENLA,Xenopus laevis (African clawed frog),tricarboxylic acid cycle [GO:0006099] comp138688_c0_seq5,1385,39.8556,0.56007572,451,914,,9.00E-50,Q5ZLX5,Zinc finger Ran-binding domain-containing protein 2,Zinc finger Ran-binding domain-containing protein 2,GO:0003723; GO:0005634; GO:0008270,RNA binding; nucleus; zinc ion binding,PF00641;,6.00E-78,CHOYP_ZRAB2.1.1,1.00E-91,ruditapes_c10261,,,,,ZRAB2_CHICK,Gallus gallus (Chicken), comp138691_c0_seq1,2654,42.6526,0.60159565,2,35,,,,,,,,,6.00E-81,CHOYP_E41L3.2.2,,,,,,,,, comp138691_c0_seq2,2636,42.7921,0.60179726,0,59,,9.00E-52,P26045,Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1),Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1),GO:0005737; GO:0005856; GO:0009898; GO:0051045; GO:0045930; GO:0004725,cytoplasm; cytoskeleton; internal side of plasma membrane; negative regulation of membrane protein ectodomain proteolysis; negative regulation of mitotic cell cycle; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,,,,,,,,,PTN3_HUMAN,Homo sapiens (Human),liver regeneration [GO:0097421]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649] comp138691_c0_seq3,2492,41.9743,0.56011339,0,225,female,2.00E-132,Q9WV92,"Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]","Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]",GO:0006915; GO:0005911; GO:0030866; GO:0030865; GO:0005737; GO:0007016; GO:0005856; GO:0019898; GO:0044224; GO:0043217; GO:0048812; GO:0030913; GO:0033270; GO:0005886; GO:0071205; GO:0002175; GO:0072659; GO:0008360; GO:0005200,apoptotic process; cell-cell junction; cortical actin cytoskeleton organization; cortical cytoskeleton organization; cytoplasm; cytoskeletal anchoring at plasma membrane; cytoskeleton; extrinsic to membrane; juxtaparanode region of axon; myelin maintenance; neuron projection morphogenesis; paranodal junction assembly; paranode region of axon; plasma membrane; protein localization to juxtaparanode region of axon; protein localization to paranode region of axon; protein localization to plasma membrane; regulation of cell shape; structural constituent of cytoskeleton,PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;,6.00E-81,CHOYP_E41L3.2.2,2.00E-52,ruditapes_c7017,,,,,E41L3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360] comp138695_c0_seq1,1491,42.1194,0.80209394,18,154,,8.00E-88,Q02083,N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta],N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta],GO:0005737; GO:0016810; GO:0006629; GO:0005764,"cytoplasm; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; lipid metabolic process; lysosome",PF02275;PF15508;,,,1.00E-34,ruditapes_c14621,,,,,NAAA_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629]; neurotransmitter secretion [GO:0007269] comp138695_c0_seq4,1170,42.2222,0.90359455,10,52,,3.00E-70,Q02083,N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta],N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta],GO:0005737; GO:0016810; GO:0006629; GO:0005764,"cytoplasm; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; lipid metabolic process; lysosome",PF02275;PF15508;,,,,,,,,,NAAA_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629]; neurotransmitter secretion [GO:0007269] comp138696_c0_seq1,1300,35.3077,1.05254907,32,493,,,,,,,,,,,4.00E-14,ruditapes_c19117,,,,,,, comp138697_c4_seq2,891,34.4557,0.56834665,1031,5979,,1.00E-28,P62255,"Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]","Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]",GO:0005524; GO:0070936; GO:0070534; GO:0006511; GO:0004842,ATP binding; protein K48-linked ubiquitination; protein K63-linked ubiquitination; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00179;,,,,,,,,,UB2G1_RAT,Rattus norvegicus (Rat),protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138697_c4_seq3,1093,34.1263,0.66349042,345,1460,,,,,,,,,2.00E-39,CHOYP_UBCD1.1.2,,,,,,,,, comp138697_c4_seq6,877,34.2075,0.54718732,407,1524,,9.00E-98,P25867,Ubiquitin-conjugating enzyme E2-17 kDa (EC 6.3.2.19) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0051276; GO:0001751; GO:0008054; GO:0048132; GO:0030718; GO:0007140; GO:0005875; GO:0007067; GO:0016322; GO:0045676; GO:0031647; GO:0007286; GO:0004842,ATP binding; chromosome organization; compound eye photoreceptor cell differentiation; cyclin catabolic process; female germ-line stem cell division; germ-line stem cell maintenance; male meiosis; microtubule associated complex; mitosis; neuron remodeling; regulation of R7 cell differentiation; regulation of protein stability; spermatid development; ubiquitin-protein ligase activity,PF00179;,2.00E-114,CHOYP_UBC2.1.3,9.00E-128,ruditapes2_c11,,,,,UBCD1_DROME,Drosophila melanogaster (Fruit fly),chromosome organization [GO:0051276]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; female germ-line stem cell asymmetric division [GO:0048132]; germ-line stem cell population maintenance [GO:0030718]; male meiosis [GO:0007140]; mitotic nuclear division [GO:0007067]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; neurogenesis [GO:0022008]; neuron remodeling [GO:0016322]; oogenesis [GO:0048477]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of protein stability [GO:0031647]; regulation of R7 cell differentiation [GO:0045676]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138697_c4_seq8,1493,33.1547,0.61029439,0,6,,2.00E-24,Q8IWF7,Putative ubiquitin-conjugating enzyme E2 D2-like protein (Ubiquitin carrier protein D2-like) (Ubiquitin-conjugating enzyme E2D N-terminal-like) (Ubiquitin-protein ligase D2-like),Putative ubiquitin-conjugating enzyme E2 D2-like protein (Ubiquitin carrier protein D2-like) (Ubiquitin-conjugating enzyme E2D N-terminal-like) (Ubiquitin-protein ligase D2-like),GO:0016881,acid-amino acid ligase activity,PF00179;,3.00E-107,CHOYP_UBC2.1.3,6.00E-13,ruditapes_c31561,,,,,U2D2L_HUMAN,Homo sapiens (Human), comp138703_c0_seq1,1003,38.6839,0.5801877,214,2067,,1.00E-85,Q6PFL8,Thymocyte nuclear protein 1,Thymocyte nuclear protein 1,GO:0005634,nucleus,PF01878;,,,,,,,,,THYN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp138705_c0_seq3,1432,35.8939,0.71240403,17,98,,4.00E-07,E1BD59,E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (Tripartite motif-containing protein 56),E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (Tripartite motif-containing protein 56),GO:0005737; GO:0051607; GO:0032608; GO:0070534; GO:0034340; GO:0004842; GO:0008270,cytoplasm; defense response to virus; interferon-beta production; protein K63-linked ubiquitination; response to type I interferon; ubiquitin-protein ligase activity; zinc ion binding,PF00643;PF13445;,,,,,,,,,TRI56_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; interferon-beta production [GO:0032608]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340] comp138706_c1_seq1,2504,42.4121,0.73900545,50,148,,1.00E-164,Q6GVH4,Gametogenetin-binding protein 2 (Protein ZNF403),Gametogenetin-binding protein 2 (Protein ZNF403),GO:0030154; GO:0005737; GO:0007275; GO:0007283,cell differentiation; cytoplasm; multicellular organismal development; spermatogenesis,,2.00E-163,CHOYP_GGNB2.1.1,,,,,,,GGNB2_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp138708_c0_seq1,2555,45.1663,0.84436142,421,5475,,6.00E-49,P22105,Tenascin-X (TN-X) (Hexabrachion-like protein),Tenascin-X (TN-X) (Hexabrachion-like protein),GO:0030036; GO:0007155; GO:0016337; GO:0007160; GO:0030199; GO:0032963; GO:0048251; GO:0043206; GO:0005615; GO:0006631; GO:0008201; GO:0005178; GO:0005622; GO:0005578; GO:0043506; GO:0006641,actin cytoskeleton organization; cell adhesion; cell-cell adhesion; cell-matrix adhesion; collagen fibril organization; collagen metabolic process; elastic fiber assembly; extracellular fibril organization; extracellular space; fatty acid metabolic process; heparin binding; integrin binding; intracellular; proteinaceous extracellular matrix; regulation of JUN kinase activity; triglyceride metabolic process,PF07974;PF00147;PF00041;PF12661;,,,,,,,,,TENX_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; fatty acid metabolic process [GO:0006631]; regulation of JUN kinase activity [GO:0043506]; single organismal cell-cell adhesion [GO:0016337]; triglyceride metabolic process [GO:0006641] comp138709_c1_seq2,1347,41.0542,0.28798819,17,0,,3.00E-07,D5CE05,O-acetyl-ADP-ribose deacetylase (EC 3.5.1.-) (Regulator of RNase III activity),O-acetyl-ADP-ribose deacetylase (EC 3.5.1.-) (Regulator of RNase III activity),GO:0019213; GO:0060701; GO:0001883; GO:0042278; GO:0008428,deacetylase activity; negative regulation of ribonuclease activity; purine nucleoside binding; purine nucleoside metabolic process; ribonuclease inhibitor activity,PF01661;,,,,,,,,,YMDB_ENTCC,Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56),negative regulation of ribonuclease activity [GO:0060701]; purine nucleoside metabolic process [GO:0042278] comp138709_c1_seq3,2549,42.8403,0.48199773,214,177,,1.00E-63,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,3.00E-15,CHOYP_PARP14.14.22,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138712_c1_seq2,1778,35.6018,0.80182771,242,115,,5.00E-24,P50540,Max-interacting protein 1 (Max interactor 1),Max-interacting protein 1 (Max interactor 1),GO:0003677; GO:0000122; GO:0005634; GO:0006351,"DNA binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF00010;,5.00E-74,CHOYP_PEX5.1.2,1.00E-155,ruditapes_c2216,,,,,MXI1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp138713_c0_seq1,2118,46.1284,0.52533817,18,0,,3.00E-26,Q09853,Protein MON2 homolog,Protein MON2 homolog,GO:0005794; GO:0000139; GO:0005829; GO:0006897; GO:0005768; GO:0005085; GO:0043234; GO:0006623,Golgi apparatus; Golgi membrane; cytosol; endocytosis; endosome; guanyl-nucleotide exchange factor activity; protein complex; protein targeting to vacuole,PF16213;PF16206;PF12783;,1.00E-177,CHOYP_MON2.1.1,,,,,,,MON2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; protein targeting to vacuole [GO:0006623] comp138713_c0_seq2,1965,49.771,0.46048907,0,0,,2.00E-21,Q9Y6D5,Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2),Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2),GO:0005086; GO:0050811; GO:0000139; GO:0006893; GO:0032279; GO:0005879; GO:0030054; GO:0016023; GO:0031410; GO:0005829; GO:0043197; GO:0010256; GO:0007032; GO:0006887; GO:0035556; GO:0005815; GO:0048471; GO:0032760; GO:0034237; GO:0015031; GO:0001881; GO:0055037; GO:0032012; GO:0032280; GO:0005802,ARF guanyl-nucleotide exchange factor activity; GABA receptor binding; Golgi membrane; Golgi to plasma membrane transport; asymmetric synapse; axonemal microtubule; cell junction; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; dendritic spine; endomembrane system organization; endosome organization; exocytosis; intracellular signal transduction; microtubule organizing center; perinuclear region of cytoplasm; positive regulation of tumor necrosis factor production; protein kinase A regulatory subunit binding; protein transport; receptor recycling; recycling endosome; regulation of ARF protein signal transduction; symmetric synapse; trans-Golgi network,PF16213;PF09324;PF01369;PF12783;,,,,,,,,,BIG2_HUMAN,Homo sapiens (Human),endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012] comp138713_c0_seq3,2570,48.1712,0.50337943,5,3,,0,Q6GP04,Protein MON2 homolog,Protein MON2 homolog,GO:0015031,protein transport,PF16213;PF09324;PF16206;PF12783;,0,CHOYP_MON2.1.1,,,,,,,MON2_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp138713_c0_seq5,1932,46.7391,0.56952903,13,0,,0,Q80TL7,Protein MON2 homolog (Protein SF21),Protein MON2 homolog (Protein SF21),GO:0005086; GO:0006895; GO:0030036; GO:0015031; GO:0005802,ARF guanyl-nucleotide exchange factor activity; Golgi to endosome transport; actin cytoskeleton organization; protein transport; trans-Golgi network,PF16213;PF09324;PF16206;PF12783;,,,,,,,,,MON2_MOUSE,Mus musculus (Mouse),Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] comp138713_c0_seq6,1547,43.8268,0.55461107,0,0,,8.00E-23,P48563,Protein MON2,Protein MON2,GO:0005794; GO:0000139; GO:0006895; GO:0005829; GO:0006897; GO:0005768; GO:0019898; GO:0005085; GO:0015031; GO:0005802,Golgi apparatus; Golgi membrane; Golgi to endosome transport; cytosol; endocytosis; endosome; extrinsic to membrane; guanyl-nucleotide exchange factor activity; protein transport; trans-Golgi network,PF16213;PF16206;PF12783;,,,,,,,,,MON2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),endocytosis [GO:0006897]; Golgi to endosome transport [GO:0006895]; protein targeting to vacuole [GO:0006623]; transport [GO:0006810] comp138713_c0_seq7,1327,48.5305,0.55075067,0,0,,1.00E-07,P11075,Protein transport protein SEC7,Protein transport protein SEC7,GO:0005086; GO:0006888; GO:0005798; GO:0000045; GO:0005829; GO:0006891; GO:0005770; GO:0015031; GO:0032012; GO:0005802,ARF guanyl-nucleotide exchange factor activity; ER to Golgi vesicle-mediated transport; Golgi-associated vesicle; autophagic vacuole assembly; cytosol; intra-Golgi vesicle-mediated transport; late endosome; protein transport; regulation of ARF protein signal transduction; trans-Golgi network,PF16213;PF09324;PF01369;PF12783;,,,,,,,,,SEC7_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),autophagosome assembly [GO:0000045]; ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] comp138713_c0_seq9,1124,48.7544,0.36002429,0,0,,,,,,,,,5.00E-135,CHOYP_MON2.1.1,,,,,,,,, comp138718_c0_seq1,1872,33.4936,0.44039064,105,521,,1.00E-11,Q9BVK6,Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25),Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25),GO:0048205; GO:0007030; GO:0005783; GO:0005789; GO:0005793; GO:0033116; GO:0016021; GO:0010638; GO:0015031; GO:0030140,COPI coating of Golgi vesicle; Golgi organization; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; positive regulation of organelle organization; protein transport; trans-Golgi network transport vesicle,PF01105;,,,,,,,,,TMED9_HUMAN,Homo sapiens (Human),"COPI coating of Golgi vesicle [GO:0048205]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; positive regulation of organelle organization [GO:0010638]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp138718_c1_seq2,1760,36.8182,0.40335955,0,0,,2.00E-16,Q5B5L5,Endoplasmic reticulum vesicle protein 25,Endoplasmic reticulum vesicle protein 25,GO:0030134; GO:0000139; GO:0005789; GO:0016021; GO:0015031; GO:0016192,ER to Golgi transport vesicle; Golgi membrane; endoplasmic reticulum membrane; integral to membrane; protein transport; vesicle-mediated transport,PF01105;,,,,,,,,,TMEDA_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp138718_c1_seq5,1777,36.5785,0.49040827,0,0,,1.00E-107,B4JG34,Transmembrane emp24 domain-containing protein eca,Transmembrane emp24 domain-containing protein eca,GO:0009953; GO:0005789; GO:0016021; GO:0006810,dorsal/ventral pattern formation; endoplasmic reticulum membrane; integral to membrane; transport,PF01105;,2.00E-148,CHOYP_BRAFLDRAFT_124027.1.2,,,,,,,TMEDE_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi),dorsal/ventral pattern formation [GO:0009953]; transport [GO:0006810] comp138720_c1_seq2,767,39.1134,0.65910948,3,9,,4.00E-28,A2BIG9,LSM domain-containing protein 1,"N-alpha-acetyltransferase 38, NatC auxiliary subunit (LSM domain-containing protein 1)",,,PF01423;,9.00E-22,CHOYP_LOC762575.1.1,3.00E-38,ruditapes_c9912,,,,,LSMD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of apoptotic process [GO:0043066] comp138723_c0_seq2,1391,40.4026,0.49856122,2,14,,1.00E-106,Q91ZW2,GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1),GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1),GO:0007219; GO:0001525; GO:0005783; GO:0006004; GO:0008417; GO:0007507; GO:0016020; GO:0007399; GO:0046922; GO:0006493; GO:0001756,Notch signaling pathway; angiogenesis; endoplasmic reticulum; fucose metabolic process; fucosyltransferase activity; heart development; membrane; nervous system development; peptide-O-fucosyltransferase activity; protein O-linked glycosylation; somitogenesis,PF10250;,5.00E-41,CHOYP_BRAFLDRAFT_87806.1.1,1.00E-26,ruditapes_c20145,,,,,OFUT1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; fucose metabolic process [GO:0006004]; heart development [GO:0007507]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; protein O-linked fucosylation [GO:0036066]; protein O-linked glycosylation [GO:0006493]; somitogenesis [GO:0001756] comp138725_c0_seq1,909,29.3729,0.77636313,195,624,,,,,,,,,,,4.00E-12,ruditapes_c9054,,,,,,, comp138727_c0_seq1,301,39.2027,0.08678257,7,79,,1.00E-36,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp138728_c0_seq1,1033,31.849,0.46006717,532,3804,,4.00E-08,Q8BGS2,BolA-like protein 2,BolA-like protein 2,,,PF01722;,2.00E-19,CHOYP_LOC100883874.1.1,3.00E-15,ruditapes2_c535,,,,,BOLA2_MOUSE,Mus musculus (Mouse), comp138730_c0_seq1,1436,39.1365,1.0609086,2353,55,,,,,,,,,2.00E-26,CHOYP_contig_047707,6.00E-76,ruditapes_c14440,,,,,,, comp138731_c0_seq1,1637,38.2407,0.47115402,84,864,,2.00E-116,Q13889,General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit),General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit),GO:0006370; GO:0000439; GO:0003684; GO:0005675; GO:0046872; GO:0000718; GO:0050434; GO:0006468; GO:0003700; GO:0006363; GO:0006362; GO:0006368; GO:0006361; GO:0006367; GO:0006283; GO:0008135; GO:0016032,"7-methylguanosine mRNA capping; core TFIIH complex; damaged DNA binding; holo TFIIH complex; metal ion binding; nucleotide-excision repair, DNA damage removal; positive regulation of viral transcription; protein phosphorylation; sequence-specific DNA binding transcription factor activity; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; translation factor activity, nucleic acid binding; viral process",PF03850;,5.00E-73,CHOYP_LOC100024026.1.1,,,3.00E-67,AM855680.p.cg.6,4,female gonad,TF2H3_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; termination of RNA polymerase I transcription [GO:0006363]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp138733_c0_seq1,1475,37.7627,0.51540336,1065,7845,,2.00E-51,Q68EV6,"39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28)","39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF00830;,,,,,,,,,RM28_XENLA,Xenopus laevis (African clawed frog), comp138736_c0_seq6,655,50.3817,1.02161979,0,0,,3.00E-09,Q7T3Q2,Cysteine-rich motor neuron 1 protein (CRIM-1),Cysteine-rich motor neuron 1 protein (CRIM-1),GO:0001568; GO:0005576; GO:0016021; GO:0043086; GO:0048570; GO:0001558; GO:0004867; GO:0001756,blood vessel development; extracellular region; integral to membrane; negative regulation of catalytic activity; notochord morphogenesis; regulation of cell growth; serine-type endopeptidase inhibitor activity; somitogenesis,PF02822;PF00219;PF00093;,,,,,,,,,CRIM1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),blood vessel development [GO:0001568]; notochord morphogenesis [GO:0048570]; regulation of cell growth [GO:0001558]; somitogenesis [GO:0001756] comp138739_c0_seq1,1458,40.9465,0.37514335,641,2211,,0,P17980,26S protease regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1),26S protease regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1),GO:0005524; GO:0016887; GO:0006977; GO:0000082; GO:0031145; GO:0002479; GO:0006915; GO:0001824; GO:0000932; GO:0005829; GO:0010467; GO:0016071; GO:0019048; GO:0043066; GO:0051436; GO:0005654; GO:0048471; GO:0051437; GO:0022624; GO:0000209; GO:0006521; GO:0003713; GO:0003714; GO:0016032,"ATP binding; ATPase activity; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; G1/S transition of mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; apoptotic process; blastocyst development; cytoplasmic mRNA processing body; cytosol; gene expression; mRNA metabolic process; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; perinuclear region of cytoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; proteasome accessory complex; protein polyubiquitination; regulation of cellular amino acid metabolic process; transcription coactivator activity; transcription corepressor activity; viral process",PF00004;,0,CHOYP_LOC100376932.1.1,3.00E-104,ruditapes_c8251,,,,,PRS6A_HUMAN,Homo sapiens (Human),"anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; blastocyst development [GO:0001824]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp138743_c1_seq1,796,36.6834,0.52466345,41,23,,2.00E-58,Q8K2X1,Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D),Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D),GO:0005524; GO:0006812; GO:0019829; GO:0005789; GO:0016021; GO:0000287; GO:0005739; GO:0004012; GO:0005886,ATP binding; cation transport; cation-transporting ATPase activity; endoplasmic reticulum membrane; integral to membrane; magnesium ion binding; mitochondrion; phospholipid-translocating ATPase activity; plasma membrane,PF00122;PF16212;PF16209;,,,,,,,,,AT10D_MOUSE,Mus musculus (Mouse),cation transport [GO:0006812] comp138743_c2_seq1,3658,42.2362,0.57787019,110,62,,,,,,,,,1.00E-97,CHOYP_AT10A.1.1,,,,,,,,, comp138743_c2_seq2,2283,41.7433,0.56850781,5,2,,1.00E-69,Q12674,Probable phospholipid-transporting ATPase DNF3 (EC 3.6.3.1),Probable phospholipid-transporting ATPase DNF3 (EC 3.6.3.1),GO:0005524; GO:0019829; GO:0016021; GO:0006886; GO:0000287; GO:0045332; GO:0004012; GO:0030140,ATP binding; cation-transporting ATPase activity; integral to membrane; intracellular protein transport; magnesium ion binding; phospholipid translocation; phospholipid-translocating ATPase activity; trans-Golgi network transport vesicle,PF00122;PF16212;PF16209;,,,,,,,,,ATC8_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),intracellular protein transport [GO:0006886]; phospholipid translocation [GO:0045332]; response to pheromone involved in conjugation with cellular fusion [GO:0000749] comp138743_c2_seq3,2587,42.4816,0.56204861,0,0,,2.00E-165,Q9P241,Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D),Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D),GO:0005524; GO:0006812; GO:0019829; GO:0005783; GO:0005789; GO:0016021; GO:0034220; GO:0000287; GO:0045332; GO:0004012; GO:0005886,ATP binding; cation transport; cation-transporting ATPase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; ion transmembrane transport; magnesium ion binding; phospholipid translocation; phospholipid-translocating ATPase activity; plasma membrane,PF00122;PF16212;PF16209;,,,,,,,,,AT10D_HUMAN,Homo sapiens (Human),cation transport [GO:0006812]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] comp138743_c2_seq4,2108,41.6983,0.51824154,7,2,,3.00E-130,O60312,Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPase class V type 10A) (Aminophospholipid translocase VA),Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPase class V type 10A) (Aminophospholipid translocase VA) (P4-ATPase flippase complex alpha subunit ATP10A),GO:0005524; GO:0019829; GO:0005783; GO:0005789; GO:0016021; GO:0034220; GO:0000287; GO:0045332; GO:0004012; GO:0005886; GO:0008360,ATP binding; cation-transporting ATPase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; ion transmembrane transport; magnesium ion binding; phospholipid translocation; phospholipid-translocating ATPase activity; plasma membrane; regulation of cell shape,PF00122;PF16212;PF16209;,1.00E-56,CHOYP_AT10A.1.1,,,,,,,AT10A_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332]; regulation of cell shape [GO:0008360] comp138745_c0_seq1,4864,29.8931,0.45326549,2738,7452,,3.00E-31,Q5FWN7,Uncharacterized protein C1orf108 homolog A,Uncharacterized protein C1orf108 homolog A,,,,8.00E-26,CHOYP_AKIRIN2.1.1,,,,,,,C108A_XENLA,Xenopus laevis (African clawed frog), comp138746_c1_seq10,971,30.0721,0.50161911,0,0,,1.00E-15,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp138746_c1_seq12,504,32.3413,0.68863907,0,0,,7.00E-09,P92555,Uncharacterized mitochondrial protein AtMg01250 (ORF102),Uncharacterized mitochondrial protein AtMg01250 (ORF102),GO:0003723; GO:0006278; GO:0003964; GO:0005739,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; mitochondrion,PF00078;,,,,,,,,,M1250_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138746_c1_seq2,1385,29.0975,0.51206923,0,0,,7.00E-15,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,3.00E-18,CHOYP_LOC100490320.2.2,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp138746_c1_seq3,388,29.6392,0.60142638,0,0,,,,,,,,,1.00E-17,CHOYP_LOC100555596.2.2,,,,,,,,, comp138746_c1_seq5,480,30.625,0.36097718,6,32,,,,,,,,,6.00E-28,CHOYP_DDB_G0292452.1.1,,,,,,,,, comp138747_c0_seq1,6428,35.9988,0.59462387,2196,3644,,4.00E-145,O43390,Heterogeneous nuclear ribonucleoprotein R (hnRNP R),Heterogeneous nuclear ribonucleoprotein R (hnRNP R),GO:0003723; GO:0071013; GO:0005737; GO:0000398; GO:0005654; GO:0000166,"RNA binding; catalytic step 2 spliceosome; cytoplasm; mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding",PF00076;,4.00E-138,CHOYP_HNRPR.2.2,1.00E-59,ruditapes2_c1636,,,,,HNRPR_HUMAN,Homo sapiens (Human),"circadian rhythm [GO:0007623]; gene expression [GO:0010467]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of catalytic activity [GO:0043086]; positive regulation of mRNA catabolic process [GO:0061014]" comp138747_c0_seq2,6058,36.7118,0.58252723,8,33,,3.00E-145,O43390,Heterogeneous nuclear ribonucleoprotein R (hnRNP R),Heterogeneous nuclear ribonucleoprotein R (hnRNP R),GO:0003723; GO:0071013; GO:0005737; GO:0000398; GO:0005654; GO:0000166,"RNA binding; catalytic step 2 spliceosome; cytoplasm; mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding",PF00076;,4.00E-138,CHOYP_HNRPR.2.2,,,,,,,HNRPR_HUMAN,Homo sapiens (Human),"circadian rhythm [GO:0007623]; gene expression [GO:0010467]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of catalytic activity [GO:0043086]; positive regulation of mRNA catabolic process [GO:0061014]" comp138748_c1_seq1,1294,42.1947,1.02096081,0,9,,1.00E-43,P22071,3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)],3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)],GO:0003854; GO:0033327; GO:0051287; GO:0030325; GO:0018879; GO:0071236; GO:0071320; GO:0071549; GO:0044344; GO:0071372; GO:0071333; GO:0070301; GO:0032869; GO:0071373; GO:0071288; GO:0071406; GO:0071560; GO:0018894; GO:0035410; GO:0016101; GO:0005789; GO:0006703; GO:0008585; GO:0050756; GO:0030851; GO:0021766; GO:0017143; GO:0016021; GO:0060135; GO:0030061; GO:0006082; GO:0030728; GO:0018958; GO:0046470; GO:0006701; GO:0033591; GO:0014823; GO:0043279; GO:0046685; GO:0046686; GO:0051592; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0070542; GO:0060992; GO:0009635; GO:0010288; GO:0010226; GO:0033197; GO:0005496; GO:0004769; GO:0061370; GO:0018970,3-beta-hydroxy-delta5-steroid dehydrogenase activity; Leydig cell differentiation; NAD binding; adrenal gland development; biphenyl metabolic process; cellular response to antibiotic; cellular response to cAMP; cellular response to dexamethasone stimulus; cellular response to fibroblast growth factor stimulus; cellular response to follicle-stimulating hormone stimulus; cellular response to glucose stimulus; cellular response to hydrogen peroxide; cellular response to insulin stimulus; cellular response to luteinizing hormone stimulus; cellular response to mercury ion; cellular response to methylmercury; cellular response to transforming growth factor beta stimulus; dibenzo-p-dioxin metabolic process; dihydrotestosterone 17-beta-dehydrogenase activity; diterpenoid metabolic process; endoplasmic reticulum membrane; estrogen biosynthetic process; female gonad development; fractalkine metabolic process; granulocyte differentiation; hippocampus development; insecticide metabolic process; integral to membrane; maternal process involved in female pregnancy; mitochondrial crista; organic acid metabolic process; ovulation; phenol-containing compound metabolic process; phosphatidylcholine metabolic process; progesterone biosynthetic process; response to L-ascorbic acid; response to activity; response to alkaloid; response to arsenic-containing substance; response to cadmium ion; response to calcium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to fatty acid; response to fungicide; response to herbicide; response to lead ion; response to lithium ion; response to vitamin E; steroid binding; steroid delta-isomerase activity; testosterone biosynthetic process; toluene metabolic process,PF01073;,,,,,,,,,3BHS1_RAT,Rattus norvegicus (Rat),adrenal gland development [GO:0030325]; biphenyl metabolic process [GO:0018879]; C21-steroid hormone metabolic process [GO:0008207]; cellular response to antibiotic [GO:0071236]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to insulin stimulus [GO:0032869]; cellular response to luteinizing hormone stimulus [GO:0071373]; cellular response to mercury ion [GO:0071288]; cellular response to methylmercury [GO:0071406]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dibenzo-p-dioxin metabolic process [GO:0018894]; diterpenoid metabolic process [GO:0016101]; female gonad development [GO:0008585]; granulocyte differentiation [GO:0030851]; hippocampus development [GO:0021766]; insecticide metabolic process [GO:0017143]; Leydig cell differentiation [GO:0033327]; male gonad development [GO:0008584]; maternal process involved in female pregnancy [GO:0060135]; organic acid metabolic process [GO:0006082]; ovulation [GO:0030728]; phenol-containing compound metabolic process [GO:0018958]; phosphatidylcholine metabolic process [GO:0046470]; progesterone biosynthetic process [GO:0006701]; response to activity [GO:0014823]; response to alkaloid [GO:0043279]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to fungicide [GO:0060992]; response to herbicide [GO:0009635]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to vitamin E [GO:0033197]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]; toluene metabolic process [GO:0018970] comp138750_c0_seq2,2306,48.3088,0.97029068,9,3,,2.00E-20,Q7XBS0,Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3),Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3),GO:0016021; GO:0005886; GO:0015293; GO:0015204,integral to membrane; plasma membrane; symporter activity; urea transmembrane transporter activity,PF00474;,,,,,,,,,DUR3_ORYSJ,Oryza sativa subsp. japonica (Rice),urea transmembrane transport [GO:0071918] comp138750_c0_seq3,2405,48.5239,0.98015663,20,0,,2.00E-20,O94469,Probable urea active transporter 1,Probable urea active transporter 1,GO:0016021; GO:0005634; GO:0005886; GO:0015204,integral to membrane; nucleus; plasma membrane; urea transmembrane transporter activity,PF00474;,,,,,,,,,DUR31_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),spermidine transport [GO:0015848]; urea transmembrane transport [GO:0071918] comp138754_c1_seq1,424,42.4528,0.16741165,6,70,,3.00E-29,A4QNS7,WD repeat-containing protein mio-B,WD repeat-containing protein mio-B,,,PF17034;,,,,,,,,,MIOB_XENLA,Xenopus laevis (African clawed frog), comp138755_c0_seq3,2045,40.4401,1.09244877,1864,23,,1.00E-26,Q32LM4,F-box only protein 39,F-box only protein 39,,,PF12937;,,,,,,,,,FBX39_BOVIN,Bos taurus (Bovine),SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp138756_c0_seq1,2477,36.5765,0.54548738,3766,18703,,3.00E-58,P38656,Lupus La protein homolog (La autoantigen homolog) (La ribonucleoprotein),Lupus La protein homolog (La autoantigen homolog) (La ribonucleoprotein),GO:0003723; GO:0000166; GO:0005634; GO:0030529; GO:0008033,RNA binding; nucleotide binding; nucleus; ribonucleoprotein complex; tRNA processing,PF05383;PF00076;PF08777;,8.00E-16,CHOYP_LA.1.1,,,,,,,LA_RAT,Rattus norvegicus (Rat),tRNA processing [GO:0008033] comp138757_c2_seq1,1816,40.3084,0.58557131,26,7,,7.00E-35,Q569C3,Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1),Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1),GO:0006281; GO:0035520; GO:0005634; GO:0006282; GO:0009411; GO:0004221; GO:0006511; GO:0004843,DNA repair; monoubiquitinated protein deubiquitination; nucleus; regulation of DNA repair; response to UV; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,,,,,,,,,UBP1_RAT,Rattus norvegicus (Rat),DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138757_c2_seq2,1585,41.0726,0.55606959,0,0,,3.00E-35,Q29RP1,Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1),Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1),GO:0006281; GO:0035520; GO:0005634; GO:0006282; GO:0009411; GO:0004221; GO:0006511; GO:0004843,DNA repair; monoubiquitinated protein deubiquitination; nucleus; regulation of DNA repair; response to UV; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,2.00E-33,CHOYP_LOC100366443.1.1,,,,,,,UBP1_BOVIN,Bos taurus (Bovine),DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511] comp138758_c0_seq2,3427,42.2819,0.59587459,0,0,,2.00E-107,Q8TF05,Serine/threonine-protein phosphatase 4 regulatory subunit 1,Serine/threonine-protein phosphatase 4 regulatory subunit 1,GO:0030289; GO:0030362; GO:0006468; GO:0007165,protein phosphatase 4 complex; protein phosphatase type 4 regulator activity; protein phosphorylation; signal transduction,PF02985;PF15017;,2.00E-125,CHOYP_PP4R1.1.1,,,,,,,PP4R1_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] comp138758_c0_seq3,2272,40.9771,0.58892016,4,4,,2.00E-110,Q8VI02,Serine/threonine-protein phosphatase 4 regulatory subunit 1,Serine/threonine-protein phosphatase 4 regulatory subunit 1,,,PF02985;,,,,,,,,,PP4R1_RAT,Rattus norvegicus (Rat),signal transduction [GO:0007165] comp138758_c0_seq4,3484,42.279,0.58539731,0,0,,5.00E-107,Q8TF05,Serine/threonine-protein phosphatase 4 regulatory subunit 1,Serine/threonine-protein phosphatase 4 regulatory subunit 1,GO:0030289; GO:0030362; GO:0006468; GO:0007165,protein phosphatase 4 complex; protein phosphatase type 4 regulator activity; protein phosphorylation; signal transduction,PF02985;PF15017;,3.00E-125,CHOYP_PP4R1.1.1,,,,,,,PP4R1_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] comp138759_c1_seq1,600,41.3333,0.28250146,26,327,,,,,,,,,2.00E-35,CHOYP_DBT.1.1,,,,,,,,, comp138759_c3_seq1,2648,36.4048,0.37698759,84,545,,2.00E-125,P53395,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)","Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)",GO:0048037; GO:0043754; GO:0046949; GO:0005759; GO:0005739,cofactor binding; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; fatty-acyl-CoA biosynthetic process; mitochondrial matrix; mitochondrion,PF00198;PF00364;PF02817;,,,,,,,,,ODB2_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp138759_c3_seq2,2460,36.2195,0.33669969,78,830,,6.00E-121,P11182,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)","Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)",GO:0009083; GO:0034641; GO:0048037; GO:0043754; GO:0046949; GO:0015630; GO:0005947; GO:0042645,branched-chain amino acid catabolic process; cellular nitrogen compound metabolic process; cofactor binding; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; fatty-acyl-CoA biosynthetic process; microtubule cytoskeleton; mitochondrial alpha-ketoglutarate dehydrogenase complex; mitochondrial nucleoid,PF00198;PF00364;PF02817;,,,,,,,,,ODB2_HUMAN,Homo sapiens (Human),branched-chain amino acid catabolic process [GO:0009083]; glyoxylate metabolic process [GO:0046487] comp138759_c3_seq3,1762,39.0465,0.34382218,4,39,,3.00E-130,P53395,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)","Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)",GO:0048037; GO:0043754; GO:0046949; GO:0005759; GO:0005739,cofactor binding; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; fatty-acyl-CoA biosynthetic process; mitochondrial matrix; mitochondrion,PF00198;PF00364;PF02817;,2.00E-59,CHOYP_DBT.1.1,,,,,,,ODB2_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp138760_c0_seq1,706,39.0935,0.66855926,0,11,,7.00E-07,P34284,Uncharacterized F-box/LRR-repeat protein C02F5.7,Uncharacterized F-box/LRR-repeat protein C02F5.7,,,PF12937;PF00560;PF13516;,9.00E-66,CHOYP_SMP_176410.1.1,,,,,,,YKK7_CAEEL,Caenorhabditis elegans,dauer entry [GO:0043053]; defecation rhythm [GO:0035882] comp138760_c0_seq3,786,38.0407,0.63467845,7,0,,1.00E-05,A1A5X2,F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7),F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7),GO:0005737; GO:0005815; GO:0016567,cytoplasm; microtubule organizing center; protein ubiquitination,PF12937;PF13516;,,,,,,,,,FBXL7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp138760_c3_seq16,1591,39.2206,0.55687265,0,0,,,,,,,,,,,4.00E-123,ruditapes_c24273,,,,,,, comp138760_c3_seq8,1818,38.8339,0.58402381,7,7,,,,,,,,,3.00E-153,CHOYP_SMP_176410.1.1,,,,,,,,, comp138760_c3_seq9,415,37.8313,0.81276929,3,0,,,,,,,,,5.00E-22,CHOYP_SMP_176410.1.1,,,,,,,,, comp138762_c0_seq1,2220,37.7928,0.38050376,750,4500,,0,P12694,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)","2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)",GO:0003863; GO:0003826; GO:0009083; GO:0016831; GO:0034641; GO:0046872; GO:0005947,3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; alpha-ketoacid dehydrogenase activity; branched-chain amino acid catabolic process; carboxy-lyase activity; cellular nitrogen compound metabolic process; metal ion binding; mitochondrial alpha-ketoglutarate dehydrogenase complex,PF00676;,7.00E-143,CHOYP_NEMVEDRAFT_V1G183894.1.1,,,,,,,ODBA_HUMAN,Homo sapiens (Human),branched-chain amino acid catabolic process [GO:0009083]; glyoxylate metabolic process [GO:0046487] comp138763_c1_seq1,1668,36.3909,0.47471847,121,616,,2.00E-13,Q5UPG5,Putative ankyrin repeat protein L93,Putative ankyrin repeat protein L93,,,PF12796;PF13606;,3.00E-57,CHOYP_contig_047167,,,,,,,YL093_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp138765_c0_seq3,2716,38.8439,0.36747896,253,1909,,2.00E-150,Q6DRI7,ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51),ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF00271;,7.00E-49,CHOYP_LOC100377194.2.2,,,,,,,DDX51_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp138769_c3_seq1,230,43.4783,0.73950978,57,276,,,,,,,,,5.00E-12,CHOYP_contig_051262,4.00E-11,ruditapes_c26741,,,,,,, comp138770_c1_seq1,1510,39.3377,0.92627867,12,64,,8.00E-18,P34998,Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1),Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1),GO:0007190; GO:0045177; GO:0048148; GO:0048149; GO:0048266; GO:0015056; GO:0051458; GO:0051424; GO:0043404; GO:0030425; GO:0042755; GO:0007204; GO:0030855; GO:0007565; GO:0021854; GO:0006955; GO:0005887; GO:0035641; GO:0060291; GO:0007613; GO:0005771; GO:0032099; GO:0032811; GO:1901215; GO:1901386; GO:0043025; GO:0007218; GO:0007567; GO:0007200; GO:0010579; GO:0043306; GO:2000852; GO:0001666; GO:0035902; GO:0005802; GO:0031982; GO:0008542,activation of adenylate cyclase activity; apical part of cell; behavioral response to cocaine; behavioral response to ethanol; behavioral response to pain; corticotrophin-releasing factor receptor activity; corticotropin secretion; corticotropin-releasing hormone binding; corticotropin-releasing hormone receptor activity; dendrite; eating behavior; elevation of cytosolic calcium ion concentration; epithelial cell differentiation; female pregnancy; hypothalamus development; immune response; integral to plasma membrane; locomotory exploration behavior; long-term synaptic potentiation; memory; multivesicular body; negative regulation of appetite; negative regulation of epinephrine secretion; negative regulation of neuron death; negative regulation of voltage-gated calcium channel activity; neuronal cell body; neuropeptide signaling pathway; parturition; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; positive regulation of mast cell degranulation; regulation of corticosterone secretion; response to hypoxia; response to immobilization stress; trans-Golgi network; vesicle; visual learning,PF00002;PF02793;,,,,,,,,,CRFR1_HUMAN,Homo sapiens (Human),activation of adenylate cyclase activity [GO:0007190]; cell surface receptor signaling pathway [GO:0007166]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; corticotropin secretion [GO:0051458]; female pregnancy [GO:0007565]; immune response [GO:0006955]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; parturition [GO:0007567]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579]; regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010578]; regulation of corticosterone secretion [GO:2000852] comp138770_c1_seq2,1554,38.9961,0.89886391,20,56,,3.00E-50,O97827,Latrophilin-3,Adhesion G protein-coupled receptor L3 (Latrophilin-3),GO:0004930; GO:0030246; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,,,,,,,,,LPHN3_BOVIN,Bos taurus (Bovine),cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] comp138771_c0_seq1,1066,32.364,0.97710709,111,263,,6.00E-29,O97125,Heat shock protein 68,Heat shock protein 68,GO:0005524; GO:0008340; GO:0005811; GO:0005875; GO:0022008; GO:0031427; GO:0042594,ATP binding; determination of adult lifespan; lipid particle; microtubule associated complex; neurogenesis; response to methotrexate; response to starvation,PF00012;,4.00E-15,CHOYP_HSP7C.1.2,,,,,,,HSP68_DROME,Drosophila melanogaster (Fruit fly),determination of adult lifespan [GO:0008340]; neurogenesis [GO:0022008]; protein folding [GO:0006457]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to starvation [GO:0042594] comp138772_c0_seq3,1491,34.6076,0.45402695,119,569,,2.00E-72,Q0VCL3,Ubiquitin-like-conjugating enzyme ATG3 (EC 6.3.2.-) (Autophagy-related protein 3) (APG3-like),Ubiquitin-like-conjugating enzyme ATG3 (EC 6.3.2.-) (Autophagy-related protein 3) (APG3-like),GO:0019777; GO:0019776; GO:0000045; GO:0000153; GO:0043653; GO:0015031; GO:0016567,Atg12 ligase activity; Atg8 ligase activity; autophagic vacuole assembly; cytoplasmic ubiquitin ligase complex; mitochondrial fragmentation involved in apoptotic process; protein transport; protein ubiquitination,PF03987;PF10381;PF03986;,9.00E-89,CHOYP_ATG3.1.1,,,,,,,ATG3_BOVIN,Bos taurus (Bovine),autophagosome assembly [GO:0000045]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; regulation of cilium assembly [GO:1902017] comp138772_c1_seq2,492,45.5285,0.41362701,12,35,,3.00E-24,Q2H427,Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3),Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3),GO:0006914; GO:0005737; GO:0015031,autophagy; cytoplasm; protein transport,PF03987;PF10381;PF03986;,8.00E-52,CHOYP_ATG3.1.1,,,,,,,ATG3_CHAGB,Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus),autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein targeting to membrane [GO:0006612] comp138773_c0_seq1,1574,41.6137,0.44670731,0,16,,5.00E-58,Q9LPS9,Pirin-like protein At1g50590,Pirin-like protein At1g50590,GO:0005634,nucleus,PF02678;PF05726;,,,,,,,,,PIRL1_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp138773_c0_seq2,1599,41.0882,0.45100083,0,46,,1.00E-62,Q9SEE4,Pirin-like protein,Pirin-like protein,GO:0005634,nucleus,PF02678;PF05726;,,,,,,,,,PIRL_SOLLC,Solanum lycopersicum (Tomato) (Lycopersicon esculentum), comp138774_c0_seq1,1527,38.4414,0.78509072,0,0,,1.00E-14,Q62210,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Inhibitor of apoptosis protein 2) (IAP-2) (mIAP-2) (mIAP2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2),GO:0035631; GO:0006915; GO:0005737; GO:0009898; GO:0070266; GO:0060546; GO:1902443; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0070936; GO:0070534; GO:0042981; GO:0051726; GO:2000377; GO:0006355; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; apoptotic process; cytoplasm; internal side of plasma membrane; necroptosis; negative regulation of necroptosis; negative regulation of ripoptosome assembly involved in necroptosis; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein K63-linked ubiquitination; regulation of apoptotic process; regulation of cell cycle; regulation of reactive oxygen species metabolic process; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_MOUSE,Mus musculus (Mouse),"inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp138774_c0_seq2,1653,38.4755,0.77391315,0,0,,2.00E-39,Q8NCJ5,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,,,,,,,,,SPRY3_HUMAN,Homo sapiens (Human), comp138774_c0_seq3,1615,39.1331,0.7813057,0,0,,8.00E-42,Q8NCJ5,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,,,,,,,,,SPRY3_HUMAN,Homo sapiens (Human), comp138774_c0_seq4,968,32.7479,0.84898537,0,5,,3.00E-15,Q62210,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Inhibitor of apoptosis protein 2) (IAP-2) (mIAP-2) (mIAP2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2),GO:0035631; GO:0006915; GO:0005737; GO:0009898; GO:0070266; GO:0060546; GO:1902443; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0070936; GO:0070534; GO:0042981; GO:0051726; GO:2000377; GO:0006355; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; apoptotic process; cytoplasm; internal side of plasma membrane; necroptosis; negative regulation of necroptosis; negative regulation of ripoptosome assembly involved in necroptosis; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein K63-linked ubiquitination; regulation of apoptotic process; regulation of cell cycle; regulation of reactive oxygen species metabolic process; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_MOUSE,Mus musculus (Mouse),"inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp138776_c3_seq1,2120,44.2925,0.48608003,4,0,,2.00E-23,A2AG06,Uncharacterized protein C17orf104 homolog,Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein),,,PF15189;,7.00E-35,CHOYP_PHUM_PHUM002690.1.1,,,,,,,CQ104_MOUSE,Mus musculus (Mouse),double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] comp138776_c3_seq2,303,37.6238,0.37717532,0,0,,8.00E-25,A2RUB1,Uncharacterized protein C17orf104,Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein),,,PF15189;,,,,,,,,,CQ104_HUMAN,Homo sapiens (Human),meiotic cell cycle [GO:0051321] comp138776_c3_seq3,2190,44.6575,0.51692609,9,0,,2.00E-23,A2AG06,Uncharacterized protein C17orf104 homolog,Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein),,,PF15189;,,,,,,,,,CQ104_MOUSE,Mus musculus (Mouse),double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] comp138776_c4_seq1,550,40.7273,0.53224035,16,0,,,,,,,,,1.00E-12,CHOYP_PHUM_PHUM002690.1.1,,,,,,,,, comp138777_c0_seq1,623,46.549,0.56457288,165,103,,8.00E-07,P77296,Uncharacterized protein YbeT,Uncharacterized protein YbeT,,,PF08238;,2.00E-35,CHOYP_BRAFLDRAFT_75378.1.1,,,,,,,YBET_ECOLI,Escherichia coli (strain K12), comp138778_c1_seq1,2920,45.274,0.72069914,0,0,,0,A8CVX7,Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),GO:0030030; GO:0036064; GO:0005737; GO:0016874; GO:0018095; GO:0015631,cell projection organization; cilium basal body; cytoplasm; ligase activity; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095] comp138778_c1_seq10,2808,44.5869,0.73725128,0,0,,1.00E-66,Q6EEF3,Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),GO:0006464; GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0005634; GO:0006351,"cellular protein modification process; cilium; cytoplasm; ligase activity; microtubule basal body; nucleus; transcription, DNA-dependent",PF03133;,0,CHOYP_LOC100371480.3.3,,,,,,,TTLL5_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),"cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]" comp138778_c1_seq11,3198,45.591,0.73299734,0,0,,0,A8CVX7,Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),GO:0030030; GO:0036064; GO:0005737; GO:0016874; GO:0018095; GO:0015631,cell projection organization; cilium basal body; cytoplasm; ligase activity; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095] comp138778_c1_seq12,2951,45.0017,0.70285722,0,0,,1.00E-66,Q6EEF3,Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),GO:0006464; GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0005634; GO:0006351,"cellular protein modification process; cilium; cytoplasm; ligase activity; microtubule basal body; nucleus; transcription, DNA-dependent",PF03133;,0,CHOYP_LOC100371480.3.3,,,,,,,TTLL5_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),"cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]" comp138778_c1_seq13,3976,42.1026,0.69745642,0,0,,0,A8CVX7,Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),GO:0030030; GO:0036064; GO:0005737; GO:0016874; GO:0018095; GO:0015631,cell projection organization; cilium basal body; cytoplasm; ligase activity; protein polyglutamylation; tubulin binding,PF03133;,0,CHOYP_LOC584220.1.4,,,,,,,TTLL6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095] comp138778_c1_seq5,2148,43.8547,0.70667232,4,0,,6.00E-17,Q1ECV4,Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 3),Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 3),GO:0035082; GO:0042384; GO:0035085; GO:0005874; GO:0015630; GO:0018094; GO:0070736,"axoneme assembly; cilium assembly; cilium axoneme; microtubule; microtubule cytoskeleton; protein polyglycylation; protein-glycine ligase activity, initiating",PF03133;,0,CHOYP_LOC100371480.3.3,,,,,,,TTLL3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; cilium movement [GO:0003341]; protein polyglycylation [GO:0018094] comp138778_c1_seq6,4366,43.06,0.7015693,0,0,,2.00E-65,Q6EEF3,Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5),GO:0006464; GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0005634; GO:0006351,"cellular protein modification process; cilium; cytoplasm; ligase activity; microtubule basal body; nucleus; transcription, DNA-dependent",PF03133;,0,CHOYP_LOC584220.1.4,,,,,,,TTLL5_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),"cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]" comp138778_c1_seq7,2561,43.811,0.70186984,0,0,,0,A8CVX7,Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6),GO:0030030; GO:0036064; GO:0005737; GO:0016874; GO:0018095; GO:0015631,cell projection organization; cilium basal body; cytoplasm; ligase activity; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095] comp138778_c1_seq9,2530,44.1107,0.72320235,0,0,,,,,,,,,0,CHOYP_LOC100371480.3.3,7.00E-27,ruditapes_c734,,,,,,, comp138780_c0_seq1,2574,44.3667,0.86098752,3808,0,,0,Q8CA95,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) (EC 3.1.4.35)","cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) (EC 3.1.4.35)",GO:0047555; GO:0030552; GO:0006198; GO:0030553; GO:0046069; GO:0004118; GO:0005737; GO:0046872; GO:0043949; GO:0010738; GO:0007165,"3',5'-cyclic-GMP phosphodiesterase activity; cAMP binding; cAMP catabolic process; cGMP binding; cGMP catabolic process; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; cytoplasm; metal ion binding; regulation of cAMP-mediated signaling; regulation of protein kinase A signaling cascade; signal transduction",PF01590;PF00233;,5.00E-76,CHOYP_LOC101162470.1.1,,,,,,,PDE10_MOUSE,Mus musculus (Mouse),cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165] comp138781_c0_seq1,3651,47.6582,0.54732731,0,0,,0,P21359,Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated],Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated],GO:0000165; GO:0005099; GO:0007265; GO:0030036; GO:0030325; GO:0048844; GO:0030424; GO:0048593; GO:0021987; GO:0030199; GO:0005737; GO:0030425; GO:0021897; GO:0048853; GO:0007507; GO:0031235; GO:0001889; GO:0001656; GO:0022011; GO:0043407; GO:0035021; GO:0046580; GO:0016525; GO:0048712; GO:0030336; GO:0001953; GO:0001937; GO:0048147; GO:0007406; GO:0046929; GO:0048715; GO:0045671; GO:0042992; GO:0021915; GO:0005634; GO:0001649; GO:0014065; GO:0043473; GO:0045762; GO:0001938; GO:0043525; GO:0045765; GO:0043535; GO:0045124; GO:0001952; GO:0048169; GO:0032228; GO:0001666; GO:0007519; GO:0048745; GO:0021510; GO:0048485; GO:0008542; GO:0042060,"MAPK cascade; Ras GTPase activator activity; Ras protein signal transduction; actin cytoskeleton organization; adrenal gland development; artery morphogenesis; axon; camera-type eye morphogenesis; cerebral cortex development; collagen fibril organization; cytoplasm; dendrite; forebrain astrocyte development; forebrain morphogenesis; heart development; intrinsic to internal side of plasma membrane; liver development; metanephros development; myelination in peripheral nervous system; negative regulation of MAP kinase activity; negative regulation of Rac protein signal transduction; negative regulation of Ras protein signal transduction; negative regulation of angiogenesis; negative regulation of astrocyte differentiation; negative regulation of cell migration; negative regulation of cell-matrix adhesion; negative regulation of endothelial cell proliferation; negative regulation of fibroblast proliferation; negative regulation of neuroblast proliferation; negative regulation of neurotransmitter secretion; negative regulation of oligodendrocyte differentiation; negative regulation of osteoclast differentiation; negative regulation of transcription factor import into nucleus; neural tube development; nucleus; osteoblast differentiation; phosphatidylinositol 3-kinase cascade; pigmentation; positive regulation of adenylate cyclase activity; positive regulation of endothelial cell proliferation; positive regulation of neuron apoptotic process; regulation of angiogenesis; regulation of blood vessel endothelial cell migration; regulation of bone resorption; regulation of cell-matrix adhesion; regulation of long-term neuronal synaptic plasticity; regulation of synaptic transmission, GABAergic; response to hypoxia; skeletal muscle tissue development; smooth muscle tissue development; spinal cord development; sympathetic nervous system development; visual learning; wound healing",PF13716;PF00616;,0,CHOYP_LOC100118811.1.1,,,,,,,NF1_HUMAN,Homo sapiens (Human),"actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; neural tube development [GO:0021915]; observational learning [GO:0098597]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]" comp138781_c0_seq11,4281,45.4333,0.54898835,0,0,,0,Q04690,Neurofibromin (Neurofibromatosis-related protein NF-1),Neurofibromin (Neurofibromatosis-related protein NF-1),GO:0000165; GO:0005099; GO:0007265; GO:0030036; GO:0030325; GO:0048844; GO:0030424; GO:0048593; GO:0021987; GO:0030199; GO:0005737; GO:0030425; GO:0008625; GO:0021897; GO:0048853; GO:0007507; GO:0031235; GO:0001889; GO:0001656; GO:0022011; GO:0043407; GO:0035021; GO:0016525; GO:0048712; GO:0030336; GO:0001953; GO:0001937; GO:0048147; GO:0007406; GO:0046929; GO:0048715; GO:0045671; GO:0042992; GO:0021915; GO:0001649; GO:0014065; GO:0043473; GO:0045762; GO:0001938; GO:2001241; GO:1902043; GO:0043525; GO:0043535; GO:0045124; GO:0048169; GO:0032228; GO:0001666; GO:0007519; GO:0048745; GO:0021510; GO:0048485; GO:0008542; GO:0042060,"MAPK cascade; Ras GTPase activator activity; Ras protein signal transduction; actin cytoskeleton organization; adrenal gland development; artery morphogenesis; axon; camera-type eye morphogenesis; cerebral cortex development; collagen fibril organization; cytoplasm; dendrite; extrinsic apoptotic signaling pathway via death domain receptors; forebrain astrocyte development; forebrain morphogenesis; heart development; intrinsic to internal side of plasma membrane; liver development; metanephros development; myelination in peripheral nervous system; negative regulation of MAP kinase activity; negative regulation of Rac protein signal transduction; negative regulation of angiogenesis; negative regulation of astrocyte differentiation; negative regulation of cell migration; negative regulation of cell-matrix adhesion; negative regulation of endothelial cell proliferation; negative regulation of fibroblast proliferation; negative regulation of neuroblast proliferation; negative regulation of neurotransmitter secretion; negative regulation of oligodendrocyte differentiation; negative regulation of osteoclast differentiation; negative regulation of transcription factor import into nucleus; neural tube development; osteoblast differentiation; phosphatidylinositol 3-kinase cascade; pigmentation; positive regulation of adenylate cyclase activity; positive regulation of endothelial cell proliferation; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of neuron apoptotic process; regulation of blood vessel endothelial cell migration; regulation of bone resorption; regulation of long-term neuronal synaptic plasticity; regulation of synaptic transmission, GABAergic; response to hypoxia; skeletal muscle tissue development; smooth muscle tissue development; spinal cord development; sympathetic nervous system development; visual learning; wound healing",PF13716;PF00616;,,,,,,,,,NF1_MOUSE,Mus musculus (Mouse),"actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; neural tube development [GO:0021915]; observational learning [GO:0098597]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]" comp138781_c0_seq5,3846,47.4259,0.5523378,0,0,,0,Q04690,Neurofibromin (Neurofibromatosis-related protein NF-1),Neurofibromin (Neurofibromatosis-related protein NF-1),GO:0000165; GO:0005099; GO:0007265; GO:0030036; GO:0030325; GO:0048844; GO:0030424; GO:0048593; GO:0021987; GO:0030199; GO:0005737; GO:0030425; GO:0008625; GO:0021897; GO:0048853; GO:0007507; GO:0031235; GO:0001889; GO:0001656; GO:0022011; GO:0043407; GO:0035021; GO:0016525; GO:0048712; GO:0030336; GO:0001953; GO:0001937; GO:0048147; GO:0007406; GO:0046929; GO:0048715; GO:0045671; GO:0042992; GO:0021915; GO:0001649; GO:0014065; GO:0043473; GO:0045762; GO:0001938; GO:2001241; GO:1902043; GO:0043525; GO:0043535; GO:0045124; GO:0048169; GO:0032228; GO:0001666; GO:0007519; GO:0048745; GO:0021510; GO:0048485; GO:0008542; GO:0042060,"MAPK cascade; Ras GTPase activator activity; Ras protein signal transduction; actin cytoskeleton organization; adrenal gland development; artery morphogenesis; axon; camera-type eye morphogenesis; cerebral cortex development; collagen fibril organization; cytoplasm; dendrite; extrinsic apoptotic signaling pathway via death domain receptors; forebrain astrocyte development; forebrain morphogenesis; heart development; intrinsic to internal side of plasma membrane; liver development; metanephros development; myelination in peripheral nervous system; negative regulation of MAP kinase activity; negative regulation of Rac protein signal transduction; negative regulation of angiogenesis; negative regulation of astrocyte differentiation; negative regulation of cell migration; negative regulation of cell-matrix adhesion; negative regulation of endothelial cell proliferation; negative regulation of fibroblast proliferation; negative regulation of neuroblast proliferation; negative regulation of neurotransmitter secretion; negative regulation of oligodendrocyte differentiation; negative regulation of osteoclast differentiation; negative regulation of transcription factor import into nucleus; neural tube development; osteoblast differentiation; phosphatidylinositol 3-kinase cascade; pigmentation; positive regulation of adenylate cyclase activity; positive regulation of endothelial cell proliferation; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of neuron apoptotic process; regulation of blood vessel endothelial cell migration; regulation of bone resorption; regulation of long-term neuronal synaptic plasticity; regulation of synaptic transmission, GABAergic; response to hypoxia; skeletal muscle tissue development; smooth muscle tissue development; spinal cord development; sympathetic nervous system development; visual learning; wound healing",PF13716;PF00616;,0,CHOYP_LOC100118811.1.1,,,,,,,NF1_MOUSE,Mus musculus (Mouse),"actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; neural tube development [GO:0021915]; observational learning [GO:0098597]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]" comp138781_c0_seq8,1936,47.4174,0.5516503,0,0,,,,,,,,,0,CHOYP_LOC100118811.1.1,,,,,,,,, comp138781_c0_seq9,4086,45.5458,0.54408176,0,0,,9.00E-103,P35608,Neurofibromin (Neurofibromatosis-related protein NF-1) (Fragment),Neurofibromin (Neurofibromatosis-related protein NF-1) (Fragment),GO:0005096; GO:0048147; GO:0043547,GTPase activator activity; negative regulation of fibroblast proliferation; positive regulation of GTPase activity,,,,,,,,,,NF1_CHICK,Gallus gallus (Chicken),negative regulation of fibroblast proliferation [GO:0048147] comp138781_c1_seq4,5334,44.132,0.49686884,165,18,,0,P97526,Neurofibromin (Neurofibromatosis-related protein NF-1),Neurofibromin (Neurofibromatosis-related protein NF-1),GO:0000165; GO:0005099; GO:0007265; GO:0030036; GO:0030325; GO:0048844; GO:0030424; GO:0048593; GO:0021987; GO:0030199; GO:0005737; GO:0030425; GO:0021897; GO:0048853; GO:0007507; GO:0031235; GO:0001889; GO:0001656; GO:0008017; GO:0022011; GO:0043407; GO:0046580; GO:0048147; GO:0007406; GO:0048715; GO:0042992; GO:0005634; GO:0001649; GO:0014065; GO:0043473; GO:0045762; GO:0043525; GO:0014069; GO:0043234; GO:0045765; GO:0045124; GO:0001952; GO:0045664; GO:0001666; GO:0048745; GO:0021510; GO:0048485; GO:0008542; GO:0042060,MAPK cascade; Ras GTPase activator activity; Ras protein signal transduction; actin cytoskeleton organization; adrenal gland development; artery morphogenesis; axon; camera-type eye morphogenesis; cerebral cortex development; collagen fibril organization; cytoplasm; dendrite; forebrain astrocyte development; forebrain morphogenesis; heart development; intrinsic to internal side of plasma membrane; liver development; metanephros development; microtubule binding; myelination in peripheral nervous system; negative regulation of MAP kinase activity; negative regulation of Ras protein signal transduction; negative regulation of fibroblast proliferation; negative regulation of neuroblast proliferation; negative regulation of oligodendrocyte differentiation; negative regulation of transcription factor import into nucleus; nucleus; osteoblast differentiation; phosphatidylinositol 3-kinase cascade; pigmentation; positive regulation of adenylate cyclase activity; positive regulation of neuron apoptotic process; postsynaptic density; protein complex; regulation of angiogenesis; regulation of bone resorption; regulation of cell-matrix adhesion; regulation of neuron differentiation; response to hypoxia; smooth muscle tissue development; spinal cord development; sympathetic nervous system development; visual learning; wound healing,PF13716;PF00616;,3.00E-25,CHOYP_NF1.1.1,,,,,,,NF1_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cerebral cortex development [GO:0021987]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of neuron differentiation [GO:0045664]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060] comp138782_c0_seq3,1584,33.8384,0.54049467,17,14,,1.00E-17,Q5PPN7,Coiled-coil domain-containing protein 51,Coiled-coil domain-containing protein 51,GO:0016021; GO:0005739; GO:0005634,integral to membrane; mitochondrion; nucleus,,,,,,,,,,CCD51_RAT,Rattus norvegicus (Rat), comp138785_c0_seq1,1754,36.431,0.44220821,62,290,,7.00E-85,Q921C5,Protein bicaudal D homolog 2 (Bic-D 2),Protein bicaudal D homolog 2 (Bic-D 2),GO:0005794; GO:0031410; GO:0005856; GO:0072393; GO:0072385,Golgi apparatus; cytoplasmic vesicle; cytoskeleton; microtubule anchoring at microtubule organizing center; minus-end-directed organelle transport along microtubule,PF09730;,7.00E-28,CHOYP_BICD2.1.1,,,,,,,BICD2_MOUSE,Mus musculus (Mouse),microtubule anchoring at microtubule organizing center [GO:0072393]; microtubule-based movement [GO:0007018]; minus-end-directed organelle transport along microtubule [GO:0072385] comp138785_c0_seq2,1657,39.1068,0.45302331,2,2,,,,,,,,,8.00E-71,CHOYP_BICD2.1.1,,,,,,,,, comp138785_c0_seq5,1298,41.9877,0.57119335,0,0,,6.00E-67,Q96G01,Protein bicaudal D homolog 1 (Bic-D 1),Protein bicaudal D homolog 1 (Bic-D 1),GO:0005794; GO:0006396; GO:0009653; GO:0031410; GO:0008093; GO:0005856; GO:0005829; GO:0034452; GO:0045502; GO:0072517; GO:0008298; GO:0016020; GO:0072393; GO:0072385; GO:0019048; GO:1900275; GO:1900737; GO:0048471; GO:0048260; GO:0033365; GO:0031871; GO:1900276; GO:0034063; GO:0005200; GO:0005802; GO:0016032,Golgi apparatus; RNA processing; anatomical structure morphogenesis; cytoplasmic vesicle; cytoskeletal adaptor activity; cytoskeleton; cytosol; dynactin binding; dynein binding; host cell viral assembly compartment; intracellular mRNA localization; membrane; microtubule anchoring at microtubule organizing center; minus-end-directed organelle transport along microtubule; modulation by virus of host morphology or physiology; negative regulation of phospholipase C activity; negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; perinuclear region of cytoplasm; positive regulation of receptor-mediated endocytosis; protein localization to organelle; proteinase activated receptor binding; regulation of proteinase activated receptor activity; stress granule assembly; structural constituent of cytoskeleton; trans-Golgi network; viral process,PF09730;,,,,,,,,,BICD1_HUMAN,Homo sapiens (Human),anatomical structure morphogenesis [GO:0009653]; intracellular mRNA localization [GO:0008298]; microtubule anchoring at microtubule organizing center [GO:0072393]; minus-end-directed organelle transport along microtubule [GO:0072385]; negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900737]; negative regulation of phospholipase C activity [GO:1900275]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein localization to organelle [GO:0033365]; regulation of proteinase activated receptor activity [GO:1900276]; RNA processing [GO:0006396]; stress granule assembly [GO:0034063]; viral process [GO:0016032] comp138786_c0_seq1,1259,42.8912,0.42460606,94,399,,2.00E-38,Q4PJX1,Protein odr-4 homolog (mODR-4),Protein odr-4 homolog (mODR-4),GO:0016021; GO:0016491; GO:0008270,integral to membrane; oxidoreductase activity; zinc ion binding,PF14778;,,,,,,,,,ODR4_MOUSE,Mus musculus (Mouse), comp138788_c0_seq2,1203,37.8221,0.34708862,8,28,,7.00E-36,O14095,Thioredoxin domain-containing protein plp1 (Phosducin-like protein 1),Thioredoxin domain-containing protein plp1 (Phosducin-like protein 1),GO:0045454; GO:0005829; GO:0009968; GO:0005634; GO:0006457; GO:0019236; GO:0072668,cell redox homeostasis; cytosol; negative regulation of signal transduction; nucleus; protein folding; response to pheromone; tubulin complex biogenesis,PF00085;,2.00E-46,CHOYP_LOC585158.2.2,,,,,,,YERC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell redox homeostasis [GO:0045454]; negative regulation of signal transduction [GO:0009968]; protein folding [GO:0006457]; queuosine biosynthetic process [GO:0008616]; response to pheromone [GO:0019236] comp138789_c0_seq1,1283,39.5947,0.47764925,614,860,,1.00E-68,P24392,Peroxisome biogenesis factor 2 (Peroxin-2) (Peroxisomal membrane protein 3) (Peroxisome assembly factor 1) (PAF-1),Peroxisome biogenesis factor 2 (Peroxin-2) (Peroxisomal membrane protein 3) (Peroxisome assembly factor 1) (PAF-1),GO:0016593; GO:0006635; GO:0005779; GO:0050680; GO:0048147; GO:0000122; GO:0005778; GO:0031648; GO:0016558; GO:0000038; GO:0008270,Cdc73/Paf1 complex; fatty acid beta-oxidation; integral to peroxisomal membrane; negative regulation of epithelial cell proliferation; negative regulation of fibroblast proliferation; negative regulation of transcription from RNA polymerase II promoter; peroxisomal membrane; protein destabilization; protein import into peroxisome matrix; very long-chain fatty acid metabolic process; zinc ion binding,PF04757;PF00097;,8.00E-19,CHOYP_PEX2.2.2,,,,,,,PEX2_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation [GO:0006635]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein destabilization [GO:0031648]; protein import into peroxisome matrix [GO:0016558]; very long-chain fatty acid metabolic process [GO:0000038] comp138790_c0_seq6,811,34.2787,0.17166138,1,24,,,,,,,,,,,2.00E-21,ruditapes_c5291,,,,,,, comp138792_c0_seq1,1118,43.4705,1.00607385,84,272,,,,,,,,,,,1.00E-13,ruditapes2_c522,,,,,,, comp138792_c0_seq2,1175,41.7021,0.96314566,4,198,,9.00E-09,B5QUS9,Ureidoglycolate lyase (EC 4.3.2.3) (Ureidoglycolatase),Ureidoglycolate lyase (EC 4.3.2.3) (Ureidoglycolatase),GO:0000256; GO:0006144; GO:0004848,allantoin catabolic process; purine nucleobase metabolic process; ureidoglycolate hydrolase activity,PF04115;,,,2.00E-50,ruditapes_c9216,,,,,ALLA_SALEP,Salmonella enteritidis PT4 (strain P125109),allantoin catabolic process [GO:0000256]; purine nucleobase catabolic process [GO:0006145] comp138795_c1_seq1,1745,42.808,1.12643583,21,953,,2.00E-18,O61366,Serine-enriched protein,Serine-enriched protein,,,PF07707;PF00651;,,,,,,,,,GPRS_DROME,Drosophila melanogaster (Fruit fly), comp138797_c1_seq2,1710,39.9415,1.21815962,0,0,,2.00E-28,P35382,5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) (Fragment),5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) (Fragment),GO:0030424; GO:0007610; GO:0005901; GO:0016023; GO:0043198; GO:0005887; GO:0050795; GO:0046883; GO:0004993; GO:0007210; GO:0006939,axon; behavior; caveola; cytoplasmic membrane-bounded vesicle; dendritic shaft; integral to plasma membrane; regulation of behavior; regulation of hormone secretion; serotonin receptor activity; serotonin receptor signaling pathway; smooth muscle contraction,PF00001;,,,,,,,,,5HT2A_CAVPO,Cavia porcellus (Guinea pig),behavior [GO:0007610]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; smooth muscle contraction [GO:0006939] comp138797_c1_seq5,2647,38.912,1.2300745,0,0,,7.00E-52,P35363,5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),GO:0071886; GO:0070371; GO:0007568; GO:0030424; GO:0005901; GO:0008219; GO:0016023; GO:0005829; GO:0043198; GO:0008144; GO:0005887; GO:0007613; GO:0043267; GO:0051967; GO:0014065; GO:0006661; GO:0004435; GO:0007208; GO:0043406; GO:0008284; GO:0045907; GO:0050795; GO:0014059; GO:0046883; GO:0051209; GO:0042493; GO:0006950; GO:0019233; GO:0051378; GO:0004993; GO:0030431; GO:0006939; GO:0001659,"1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; ERK1 and ERK2 cascade; aging; axon; caveola; cell death; cytoplasmic membrane-bounded vesicle; cytosol; dendritic shaft; drug binding; integral to plasma membrane; memory; negative regulation of potassium ion transport; negative regulation of synaptic transmission, glutamatergic; phosphatidylinositol 3-kinase cascade; phosphatidylinositol biosynthetic process; phosphatidylinositol phospholipase C activity; phospholipase C-activating serotonin receptor signaling pathway; positive regulation of MAP kinase activity; positive regulation of cell proliferation; positive regulation of vasoconstriction; regulation of behavior; regulation of dopamine secretion; regulation of hormone secretion; release of sequestered calcium ion into cytosol; response to drug; response to stress; sensory perception of pain; serotonin binding; serotonin receptor activity; sleep; smooth muscle contraction; temperature homeostasis",PF00001;,,,,,,,,,5HT2A_MOUSE,Mus musculus (Mouse),"activation of phospholipase C activity [GO:0007202]; aging [GO:0007568]; artery smooth muscle contraction [GO:0014824]; behavioral response to cocaine [GO:0048148]; cell death [GO:0008219]; cellular calcium ion homeostasis [GO:0006874]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; memory [GO:0007613]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cytoskeleton [GO:0044380]; regulation of behavior [GO:0050795]; regulation of dopamine secretion [GO:0014059]; regulation of hormone secretion [GO:0046883]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; serotonin receptor signaling pathway [GO:0007210]; sleep [GO:0030431]; temperature homeostasis [GO:0001659]; urinary bladder smooth muscle contraction [GO:0014832]" comp138797_c1_seq7,2647,38.912,1.22921567,0,0,,7.00E-52,P35363,5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),GO:0071886; GO:0070371; GO:0007568; GO:0030424; GO:0005901; GO:0008219; GO:0016023; GO:0005829; GO:0043198; GO:0008144; GO:0005887; GO:0007613; GO:0043267; GO:0051967; GO:0014065; GO:0006661; GO:0004435; GO:0007208; GO:0043406; GO:0008284; GO:0045907; GO:0050795; GO:0014059; GO:0046883; GO:0051209; GO:0042493; GO:0006950; GO:0019233; GO:0051378; GO:0004993; GO:0030431; GO:0006939; GO:0001659,"1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; ERK1 and ERK2 cascade; aging; axon; caveola; cell death; cytoplasmic membrane-bounded vesicle; cytosol; dendritic shaft; drug binding; integral to plasma membrane; memory; negative regulation of potassium ion transport; negative regulation of synaptic transmission, glutamatergic; phosphatidylinositol 3-kinase cascade; phosphatidylinositol biosynthetic process; phosphatidylinositol phospholipase C activity; phospholipase C-activating serotonin receptor signaling pathway; positive regulation of MAP kinase activity; positive regulation of cell proliferation; positive regulation of vasoconstriction; regulation of behavior; regulation of dopamine secretion; regulation of hormone secretion; release of sequestered calcium ion into cytosol; response to drug; response to stress; sensory perception of pain; serotonin binding; serotonin receptor activity; sleep; smooth muscle contraction; temperature homeostasis",PF00001;,4.00E-26,CHOYP_5-HT2.1.1,,,,,,,5HT2A_MOUSE,Mus musculus (Mouse),"activation of phospholipase C activity [GO:0007202]; aging [GO:0007568]; artery smooth muscle contraction [GO:0014824]; behavioral response to cocaine [GO:0048148]; cell death [GO:0008219]; cellular calcium ion homeostasis [GO:0006874]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; memory [GO:0007613]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cytoskeleton [GO:0044380]; regulation of behavior [GO:0050795]; regulation of dopamine secretion [GO:0014059]; regulation of hormone secretion [GO:0046883]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; serotonin receptor signaling pathway [GO:0007210]; sleep [GO:0030431]; temperature homeostasis [GO:0001659]; urinary bladder smooth muscle contraction [GO:0014832]" comp138798_c0_seq3,1360,36.6176,0.3578932,29,115,,5.00E-68,P13994,Coiled-coil domain-containing protein 130 (9 kDa protein),Coiled-coil domain-containing protein 130 (9 kDa protein),GO:0009615,response to virus,PF04502;,2.00E-46,CHOYP_BRAFLDRAFT_119424.1.1,,,,,,,CC130_HUMAN,Homo sapiens (Human),response to virus [GO:0009615] comp138798_c1_seq1,262,40.0763,0.48063566,0,18,,5.00E-37,Q54TR4,Coiled-coil domain-containing protein 130 homolog,Coiled-coil domain-containing protein 130 homolog,,,PF04502;,,,,,,,,,CC130_DICDI,Dictyostelium discoideum (Slime mold), comp138799_c0_seq1,1356,38.3481,0.89149731,222,7387,,7.00E-35,Q24799,Myophilin,Myophilin,,,PF00402;PF00307;,,,1.00E-20,ruditapes2_c3374,,,,,MYPH_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp138800_c0_seq2,1799,38.4102,0.37698557,25,6,,1.00E-114,Q0IHI3,Uncharacterized protein C2orf62 homolog,Ciliogenesis-associated TTC17-interacting protein,,,,8.00E-135,CHOYP_LOC100375913.1.1,,,,,,,CB062_XENLA,Xenopus laevis (African clawed frog),actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] comp138800_c0_seq4,1819,38.1528,0.3627667,82,0,,2.00E-114,Q0IHI3,Uncharacterized protein C2orf62 homolog,Ciliogenesis-associated TTC17-interacting protein,,,,,,6.00E-20,ruditapes_c11225,,,,,CB062_XENLA,Xenopus laevis (African clawed frog),actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] comp138801_c0_seq1,2297,37.0048,0.94650031,202,1676,,3.00E-06,Q9NUC0,SERTA domain-containing protein 4,SERTA domain-containing protein 4,,,PF06031;,,,,,,,,,SRTD4_HUMAN,Homo sapiens (Human), comp138803_c1_seq2,1118,30.9481,0.82389624,8,43,,,,,,,,,,,4.00E-13,ruditapes_c30227,,,,,,, comp138807_c3_seq2,1879,42.8952,0.41689007,0,0,,,,,,,,,1.00E-157,CHOYP_LOC100744356.1.1,,,,,,,,, comp138807_c3_seq4,2117,40.1512,0.31710814,0,0,,1.00E-130,Q9P2K3,REST corepressor 3,REST corepressor 3,GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01448;PF00249;,,,,,,,,,RCOR3_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp138807_c3_seq6,1728,42.5926,0.3319722,0,0,,3.00E-132,Q9P2K3,REST corepressor 3,REST corepressor 3,GO:0003677; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01448;PF00249;,3.00E-146,CHOYP_LOC100744356.1.1,,,,,,,RCOR3_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp138810_c0_seq3,1516,39.8417,0.93317995,0,0,,1.00E-06,Q1IY56,Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF),Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF),GO:0043420; GO:0004061; GO:0004328; GO:0019441,anthranilate metabolic process; arylformamidase activity; formamidase activity; tryptophan catabolic process to kynurenine,PF04199;,,,,,,,,,KYNB_DEIGD,Deinococcus geothermalis (strain DSM 11300),anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441] comp138810_c0_seq4,1005,43.0846,0.86787818,2,37,,,,,,,,,6.00E-19,CHOYP_BRAFLDRAFT_120654.1.1,,,,,,,,, comp138810_c0_seq6,676,42.0118,1.02369176,0,0,,,,,,,,,4.00E-19,CHOYP_BRAFLDRAFT_120654.1.1,,,,,,,,, comp138811_c0_seq1,2130,36.9014,0.33237807,5,2,,9.00E-37,Q6IP50,UBX domain-containing protein 1-A (SAPK substrate protein 1-A),UBX domain-containing protein 1-A (SAPK substrate protein 1-A),GO:0005737,cytoplasm,PF00627;PF00789;,,,,,,,,,UBX1A_XENLA,Xenopus laevis (African clawed frog), comp138811_c0_seq2,1923,37.0775,0.36583173,0,12,,2.00E-24,Q922Y1,UBX domain-containing protein 1 (Protein 2B28) (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein) (mY33K),UBX domain-containing protein 1 (Protein 2B28) (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein) (mY33K),GO:0071796; GO:0005737; GO:0030425; GO:0032435; GO:0031397; GO:0043025; GO:0005634,K6-linked polyubiquitin binding; cytoplasm; dendrite; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein ubiquitination; neuronal cell body; nucleus,PF00627;PF00789;,3.00E-32,CHOYP_LOC100882159.1.1,,,,,,,UBXN1_MOUSE,Mus musculus (Mouse),negative regulation of ERAD pathway [GO:1904293]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin-specific protease activity [GO:2000157] comp138811_c0_seq3,2118,36.9688,0.33310634,0,0,,2.00E-34,Q6GL77,UBX domain-containing protein 1 (SAPK substrate protein 1),UBX domain-containing protein 1 (SAPK substrate protein 1),GO:0005737,cytoplasm,PF00627;PF00789;,,,,,,,,,UBXN1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp138811_c0_seq4,2107,37.0669,0.33319291,0,0,,1.00E-31,Q6NXA9,UBX domain-containing protein 1 (SAPK substrate protein 1),UBX domain-containing protein 1 (SAPK substrate protein 1),GO:0071796; GO:0005737; GO:0032435; GO:0031397,K6-linked polyubiquitin binding; cytoplasm; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein ubiquitination,PF00627;PF00789;,1.00E-63,CHOYP_LOC579681.1.1,,,,,,,UBXN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein ubiquitination [GO:0031397] comp138811_c0_seq6,2145,36.7832,0.34595501,2,12,,1.00E-36,Q6IP50,UBX domain-containing protein 1-A (SAPK substrate protein 1-A),UBX domain-containing protein 1-A (SAPK substrate protein 1-A),GO:0005737,cytoplasm,PF00627;PF00789;,,,,,,,,,UBX1A_XENLA,Xenopus laevis (African clawed frog), comp138811_c0_seq8,1310,39.9237,0.44394902,0,2,,9.00E-38,Q6IP50,UBX domain-containing protein 1-A (SAPK substrate protein 1-A),UBX domain-containing protein 1-A (SAPK substrate protein 1-A),GO:0005737,cytoplasm,PF00627;PF00789;,7.00E-64,CHOYP_LOC579681.1.1,3.00E-41,ruditapes_c28685,,,,,UBX1A_XENLA,Xenopus laevis (African clawed frog), comp138812_c1_seq4,1178,45.1613,0.26684793,45,198,,7.00E-54,Q8IWY9,Codanin-1,Codanin-1,GO:0031497; GO:0005737; GO:0016021; GO:0008156; GO:0005634,chromatin assembly; cytoplasm; integral to membrane; negative regulation of DNA replication; nucleus,PF15296;,3.00E-18,CHOYP_LOC579713.1.1,,,,,,,CDAN1_HUMAN,Homo sapiens (Human),chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; negative regulation of DNA replication [GO:0008156]; protein localization [GO:0008104] comp138813_c0_seq1,2892,41.6321,0.43942455,266,303,,0,Q9Y5B9,FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16),FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16),GO:0006281; GO:0006260; GO:0005694; GO:0005654; GO:0006337; GO:0032786; GO:0050434; GO:0006368; GO:0016032,"DNA repair; DNA replication; chromosome; nucleoplasm; nucleosome disassembly; positive regulation of DNA-dependent transcription, elongation; positive regulation of viral transcription; transcription elongation from RNA polymerase II promoter; viral process",PF14826;PF00557;PF08512;PF08644;,,,,,,,,,SP16H_HUMAN,Homo sapiens (Human),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome disassembly [GO:0006337]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]" comp138813_c0_seq2,2032,42.4213,0.46542798,0,0,,,,,,,,,0,CHOYP_LOC100882621.2.2,,,,,,,,, comp138817_c0_seq1,1045,37.2249,0.50572166,112,630,,5.00E-63,Q9NX01,Thioredoxin-like protein 4B (Dim1-like protein),Thioredoxin-like protein 4B (Dim1-like protein),GO:0008380; GO:0006397; GO:0007067; GO:0005681,RNA splicing; mRNA processing; mitosis; spliceosomal complex,PF02966;,1.00E-40,CHOYP_TXN4B.1.1,,,,,,,TXN4B_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; spliceosomal complex assembly [GO:0000245] comp138818_c0_seq1,1213,39.0767,0.13165133,44,272,,9.00E-68,Q9Y5N5,HemK methyltransferase family member 2 (EC 2.1.1.-) (M.HsaHemK2P) (N(6)-adenine-specific DNA methyltransferase 1),HemK methyltransferase family member 2 (EC 2.1.1.-) (M.HsaHemK2P) (N(6)-adenine-specific DNA methyltransferase 1),GO:0003676; GO:0030307; GO:0043234; GO:0008276,nucleic acid binding; positive regulation of cell growth; protein complex; protein methyltransferase activity,PF05175;,,,,,,,,,HEMK2_HUMAN,Homo sapiens (Human),methylation [GO:0032259]; positive regulation of cell growth [GO:0030307]; translational termination [GO:0006415] comp138819_c0_seq1,2791,44.6435,0.49647842,484,1170,,1.00E-31,Q9HCD5,Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA),Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,2.00E-36,CHOYP_BRAFLDRAFT_118803.1.1,,,,,,,NCOA5_HUMAN,Homo sapiens (Human),"glucose homeostasis [GO:0042593]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138819_c0_seq2,2735,44.4241,0.4968021,264,469,,2.00E-31,Q9HCD5,Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA),Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,2.00E-18,CHOYP_contig_016862,,,,,,,NCOA5_HUMAN,Homo sapiens (Human),"glucose homeostasis [GO:0042593]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138821_c0_seq1,970,43.7113,0.56454811,78,347,,1.00E-50,Q6DED0,Translocating chain-associated membrane protein 1-like 1,Translocating chain-associated membrane protein 1-like 1,GO:0005789; GO:0016021; GO:0015031,endoplasmic reticulum membrane; integral to membrane; protein transport,PF08390;PF03798;,5.00E-58,CHOYP_BRAFLDRAFT_274974.1.1,,,,,,,TR1L1_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp138822_c1_seq1,1145,30.393,0.41908277,93,396,,,,,,,,,,,1.00E-14,ruditapes2_c1592,,,,,,, comp138823_c0_seq1,2301,29.4654,0.42518654,240,919,,,,,,,,,,,6.00E-15,ruditapes_c15089,,,,,,, comp138825_c1_seq1,3686,40.803,0.55695363,88,341,,0,O43747,AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 subunit gamma-1) (Adaptor protein complex AP-1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1),AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1),GO:0030119; GO:0000139; GO:0019886; GO:0030131; GO:0030665; GO:0005829; GO:0006897; GO:0006886; GO:0005765; GO:0048471; GO:0006892; GO:0008565; GO:0055037; GO:0050690; GO:0032588; GO:0005215; GO:0016032,AP-type membrane coat adaptor complex; Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin adaptor complex; clathrin-coated vesicle membrane; cytosol; endocytosis; intracellular protein transport; lysosomal membrane; perinuclear region of cytoplasm; post-Golgi vesicle-mediated transport; protein transporter activity; recycling endosome; regulation of defense response to virus by virus; trans-Golgi network membrane; transporter activity; viral process,PF01602;PF02883;,,,,,,,,,AP1G1_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690] comp138825_c1_seq2,2996,43.0908,0.58526978,0,0,,0,O43747,AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 subunit gamma-1) (Adaptor protein complex AP-1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1),AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1),GO:0030119; GO:0000139; GO:0019886; GO:0030131; GO:0030665; GO:0005829; GO:0006897; GO:0006886; GO:0005765; GO:0048471; GO:0006892; GO:0008565; GO:0055037; GO:0050690; GO:0032588; GO:0005215; GO:0016032,AP-type membrane coat adaptor complex; Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin adaptor complex; clathrin-coated vesicle membrane; cytosol; endocytosis; intracellular protein transport; lysosomal membrane; perinuclear region of cytoplasm; post-Golgi vesicle-mediated transport; protein transporter activity; recycling endosome; regulation of defense response to virus by virus; trans-Golgi network membrane; transporter activity; viral process,PF01602;PF02883;,0,CHOYP_AP1G1.1.1,,,,,,,AP1G1_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690] comp138827_c0_seq1,4461,31.7193,0.54052092,2077,7529,,,,,,,,,,,8.00E-17,ruditapes2_c2435,,,,,,, comp138830_c2_seq2,1570,44.9045,0.50647215,0,0,,6.00E-18,Q9NW75,G patch domain-containing protein 2,G patch domain-containing protein 2,GO:0010923; GO:0003676,negative regulation of phosphatase activity; nucleic acid binding,PF01585;,,,,,,,,,GPTC2_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923] comp138832_c1_seq1,1704,44.2488,0.86817569,79,503,,2.00E-27,P24463,Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1),Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,5.00E-36,CHOYP_CP4F2.1.1,,,,,,,CP3AC_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),hormone metabolic process [GO:0042445]; organic hydroxy compound metabolic process [GO:1901615]; progesterone metabolic process [GO:0042448]; steroid metabolic process [GO:0008202] comp138833_c2_seq1,1722,35.5981,0.56882873,738,1724,,1.00E-29,P82915,"28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt)","28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt)",GO:0005763; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; structural constituent of ribosome; translation,PF00886;,,,,,,,,,RT16_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp138839_c0_seq1,1953,42.7547,0.63976937,0,0,,5.00E-09,Q0U1G2,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,2.00E-59,CHOYP_LOC593522.1.2,,,,,,,PABP_PHANO,Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp138839_c0_seq2,3293,38.8096,0.64495558,112,436,,8.00E-12,A3LXL0,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,4.00E-59,CHOYP_LOC593522.2.2,,,,,,,PABP_PICST,Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis),mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060211]; regulation of translational initiation [GO:0006446] comp138839_c0_seq3,2026,44.5706,0.58899362,0,0,,5.00E-93,P23246,"Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)","Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)",GO:0003677; GO:0006310; GO:0006281; GO:0003723; GO:0000380; GO:0005737; GO:0000122; GO:0016363; GO:0000166; GO:0042382; GO:0006351,"DNA binding; DNA recombination; DNA repair; RNA binding; alternative mRNA splicing, via spliceosome; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; nucleotide binding; paraspeckles; transcription, DNA-dependent",PF08075;PF00076;,,,,,,,,,SFPQ_HUMAN,Homo sapiens (Human),"alternative mRNA splicing, via spliceosome [GO:0000380]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; mRNA processing [GO:0006397]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp138839_c0_seq5,1897,43.4897,0.62062825,0,0,,3.00E-12,A3LXL0,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,2.00E-59,CHOYP_LOC593522.1.2,,,,,,,PABP_PICST,Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis),mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060211]; regulation of translational initiation [GO:0006446] comp138839_c0_seq6,2082,43.8521,0.6058942,0,0,,8.00E-93,P23246,"Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)","Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)",GO:0003677; GO:0006310; GO:0006281; GO:0003723; GO:0000380; GO:0005737; GO:0000122; GO:0016363; GO:0000166; GO:0042382; GO:0006351,"DNA binding; DNA recombination; DNA repair; RNA binding; alternative mRNA splicing, via spliceosome; cytoplasm; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; nucleotide binding; paraspeckles; transcription, DNA-dependent",PF08075;PF00076;,3.00E-59,CHOYP_LOC593522.2.2,6.00E-84,ruditapes_c1531,,,,,SFPQ_HUMAN,Homo sapiens (Human),"alternative mRNA splicing, via spliceosome [GO:0000380]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; mRNA processing [GO:0006397]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp138840_c1_seq1,2304,37.8906,0.36521222,254,854,,2.00E-74,Q3ZBG9,Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2),Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2),GO:0016021; GO:0046872,integral to membrane; metal ion binding,PF03803;,1.00E-70,CHOYP_LOC100377321.1.1,2.00E-15,ruditapes_c15192,,,,,PLS2_BOVIN,Bos taurus (Bovine), comp138847_c0_seq1,1666,38.2353,0.82275412,0,0,,7.00E-08,Q3MHX3,RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a),RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a),GO:0002192; GO:0008380; GO:0030154; GO:0097167; GO:0010494; GO:0043153; GO:0003730; GO:0006397; GO:0035198; GO:0032055; GO:0035278; GO:0045947; GO:0016607; GO:0005730; GO:0000166; GO:0051149; GO:0097158; GO:0000381; GO:0046822; GO:0046685; GO:0051403; GO:0008270,"IRES-dependent translational initiation; RNA splicing; cell differentiation; circadian regulation of translation; cytoplasmic stress granule; entrainment of circadian clock by photoperiod; mRNA 3'-UTR binding; mRNA processing; miRNA binding; negative regulation of translation in response to stress; negative regulation of translation involved in gene silencing by miRNA; negative regulation of translational initiation; nuclear speck; nucleolus; nucleotide binding; positive regulation of muscle cell differentiation; pre-mRNA intronic pyrimidine-rich binding; regulation of alternative mRNA splicing, via spliceosome; regulation of nucleocytoplasmic transport; response to arsenic-containing substance; stress-activated MAPK cascade; zinc ion binding",PF00076;PF00098;,,,,,,,,,RBM4_BOVIN,Bos taurus (Bovine),"cap-independent translational initiation [GO:0002190]; cell differentiation [GO:0030154]; circadian regulation of translation [GO:0097167]; entrainment of circadian clock by photoperiod [GO:0043153]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]" comp138847_c0_seq3,1642,38.0633,0.80636804,0,0,,,,,,,,,6.00E-47,CHOYP_PHUM_PHUM241330.3.3,3.00E-87,ruditapes_c10863,,,,,,, comp138847_c0_seq5,1682,38.2878,0.82926859,0,0,,6.00E-39,Q8BL97,"Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7)","Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0000166; GO:0005634; GO:0008270,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nucleotide binding; nucleus; zinc ion binding",PF00076;,6.00E-47,CHOYP_PHUM_PHUM241330.3.3,3.00E-24,ruditapes2_c2224,,,,,SRSF7_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" comp138848_c0_seq1,2305,48.7636,0.49038922,44,7,,2.00E-65,Q8WXG6,MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor),MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor),GO:0017112; GO:0000187; GO:0007166; GO:0005737; GO:0005123; GO:0097194; GO:0016021; GO:0005886; GO:0030295; GO:0032483; GO:0051726; GO:1902041,Rab guanyl-nucleotide exchange factor activity; activation of MAPK activity; cell surface receptor signaling pathway; cytoplasm; death receptor binding; execution phase of apoptosis; integral to membrane; plasma membrane; protein kinase activator activity; regulation of Rab protein signal transduction; regulation of cell cycle; regulation of extrinsic apoptotic signaling pathway via death domain receptors,PF02141;PF03456;,,,,,,,,,MADD_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803] comp138848_c0_seq5,2167,48.3618,0.49161008,4,0,,9.00E-66,Q8WXG6,MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor),MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor),GO:0017112; GO:0000187; GO:0007166; GO:0005737; GO:0005123; GO:0097194; GO:0016021; GO:0005886; GO:0030295; GO:0032483; GO:0051726; GO:1902041,Rab guanyl-nucleotide exchange factor activity; activation of MAPK activity; cell surface receptor signaling pathway; cytoplasm; death receptor binding; execution phase of apoptosis; integral to membrane; plasma membrane; protein kinase activator activity; regulation of Rab protein signal transduction; regulation of cell cycle; regulation of extrinsic apoptotic signaling pathway via death domain receptors,PF02141;PF03456;,2.00E-123,CHOYP_MADD.2.3,,,,,,,MADD_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803] comp138848_c0_seq6,819,47.7411,0.7082297,0,0,,3.00E-43,O02626,"MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3)","MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3)",GO:0017112; GO:0006915; GO:0005623; GO:0005737; GO:0030421; GO:0007618; GO:0016020; GO:0018991; GO:0014057; GO:0007268,"Rab guanyl-nucleotide exchange factor activity; apoptotic process; cell; cytoplasm; defecation; mating; membrane; oviposition; positive regulation of acetylcholine secretion, neurotransmission; synaptic transmission",PF02141;PF03456;,7.00E-112,CHOYP_MADD.2.3,,,,,,,MADD_CAEEL,Caenorhabditis elegans,"apoptotic process [GO:0006915]; chemical synaptic transmission [GO:0007268]; defecation [GO:0030421]; mating [GO:0007618]; oviposition [GO:0018991]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]" comp138850_c0_seq1,1740,43.4483,0.70981824,5,57,,4.00E-29,P73133,Acetylornithine aminotransferase (ACOAT) (EC 2.6.1.11),Acetylornithine aminotransferase (ACOAT) (EC 2.6.1.11),GO:0003992; GO:0006526; GO:0005737; GO:0030170,N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity; arginine biosynthetic process; cytoplasm; pyridoxal phosphate binding,PF00202;,,,,,,,,,ARGD_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),arginine biosynthetic process [GO:0006526] comp138850_c0_seq2,1728,43.6343,0.69622709,6,84,,0,P80147,"4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)","4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)",GO:0047298; GO:0003867; GO:0032144; GO:0048148; GO:0005829; GO:0009450; GO:0005759; GO:0042135; GO:0042803; GO:0030170; GO:0032145,(S)-3-amino-2-methylpropionate transaminase activity; 4-aminobutyrate transaminase activity; 4-aminobutyrate transaminase complex; behavioral response to cocaine; cytosol; gamma-aminobutyric acid catabolic process; mitochondrial matrix; neurotransmitter catabolic process; protein homodimerization activity; pyridoxal phosphate binding; succinate-semialdehyde dehydrogenase binding,PF00202;,2.00E-47,CHOYP_GABT.1.2,,,,,,,GABT_PIG,Sus scrofa (Pig),behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135] comp138854_c1_seq1,3801,40.542,0.32039695,161,174,,7.00E-31,O74874,Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),GO:0030015; GO:0006354; GO:0003723; GO:0005829; GO:0046872; GO:0000289; GO:0090305; GO:0005634; GO:0004535; GO:0006355,"CCR4-NOT core complex; DNA-dependent transcription, elongation; RNA binding; cytosol; metal ion binding; nuclear-transcribed mRNA poly(A) tail shortening; nucleic acid phosphodiester bond hydrolysis; nucleus; poly(A)-specific ribonuclease activity; regulation of transcription, DNA-dependent",PF03372;PF13855;,,,,,,,,,CCR4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138854_c1_seq2,3771,40.5728,0.32236844,131,114,,1.00E-27,Q6L8Q7,"2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)","2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)",GO:0016787; GO:0005739,hydrolase activity; mitochondrion,PF03372;,2.00E-19,CHOYP_TCPG.1.1,2.00E-24,ruditapes_c20006,,,,,PDE12_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397] comp138855_c0_seq1,3101,40.0516,0.61960022,0,441,female,0,Q3TDQ1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (B6dom1 antigen) (Source of immunodominant MHC-associated peptides),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (B6dom1 antigen) (Source of immunodominant MHC-associated peptides),GO:0030433; GO:0043686; GO:0004579; GO:0006516; GO:0016021; GO:0008250; GO:0043687; GO:0018279; GO:0006986,ER-associated protein catabolic process; co-translational protein modification; dolichyl-diphosphooligosaccharide-protein glycotransferase activity; glycoprotein catabolic process; integral to membrane; oligosaccharyltransferase complex; post-translational protein modification; protein N-linked glycosylation via asparagine; response to unfolded protein,PF02516;,,,,,,,,,STT3B_MOUSE,Mus musculus (Mouse),co-translational protein modification [GO:0043686]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986] comp138855_c0_seq2,3083,40.1557,0.62007762,365,2465,,0,Q2KJI2,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18),GO:0043686; GO:0004579; GO:0016021; GO:0008250; GO:0018279,co-translational protein modification; dolichyl-diphosphooligosaccharide-protein glycotransferase activity; integral to membrane; oligosaccharyltransferase complex; protein N-linked glycosylation via asparagine,PF02516;,0,CHOYP_STT3A.1.1,,,,,,,STT3A_BOVIN,Bos taurus (Bovine),co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279] comp138857_c1_seq1,1291,37.1805,0.78573834,107,336,,,,,,,,,,,2.00E-17,ruditapes_c15922,,,,,,, comp138857_c1_seq2,841,46.849,0.93584706,107,153,,,,,,,,,,,1.00E-17,ruditapes2_c68,,,,,,, comp138857_c2_seq1,1264,43.6709,0.65011176,66,97,,6.00E-20,Q99315,Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)],Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,8.00E-44,CHOYP_LOC100369720.1.1,,,,,,,YG31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp138861_c1_seq1,1318,37.1017,0.73186645,394,2800,,4.00E-21,O69669,Histidine-specific methyltransferase EgtD (EC 2.1.1.44) (Histidine-alpha-N-methyltransferase),,GO:0052707; GO:0030745; GO:0052704; GO:0005886; GO:0008276,"N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine; dimethylhistidine N-methyltransferase activity; ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine; plasma membrane; protein methyltransferase activity",,,,,,,,,,EGTD_MYCTU,, comp138863_c2_seq1,3170,41.8297,0.60275099,0,0,,2.00E-74,Q8NI08,Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),GO:0016998; GO:0005622; GO:0030374; GO:0035257; GO:0005634; GO:0045944; GO:0006351,"cell wall macromolecule catabolic process; intracellular; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF01476;PF07534;,,,,,,,,,NCOA7_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp138863_c2_seq10,2585,41.3153,0.58757087,0,0,,2.00E-75,Q8NI08,Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),GO:0016998; GO:0005622; GO:0030374; GO:0035257; GO:0005634; GO:0045944; GO:0006351,"cell wall macromolecule catabolic process; intracellular; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF01476;PF07534;,1.00E-109,CHOYP_LOC655529.1.3,,,,,,,NCOA7_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp138863_c2_seq4,3203,41.6485,0.59552829,0,0,,,,,,,,,2.00E-108,CHOYP_LOC655529.2.3,,,,,,,,, comp138863_c2_seq5,3612,39.6733,0.58523764,0,0,,3.00E-74,Q8NI08,Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),GO:0016998; GO:0005622; GO:0030374; GO:0035257; GO:0005634; GO:0045944; GO:0006351,"cell wall macromolecule catabolic process; intracellular; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF01476;PF07534;,1.00E-109,CHOYP_LOC655529.1.3,,,,,,,NCOA7_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp138863_c2_seq7,4183,40.1387,0.59878015,0,0,,1.00E-73,Q8NI08,Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1),GO:0016998; GO:0005622; GO:0030374; GO:0035257; GO:0005634; GO:0045944; GO:0006351,"cell wall macromolecule catabolic process; intracellular; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF01476;PF07534;,2.00E-109,CHOYP_LOC655529.1.3,,,,,,,NCOA7_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp138863_c2_seq9,4230,40.1655,0.59243767,0,0,,,,,,,,,2.00E-108,CHOYP_LOC655529.2.3,,,,,,,,, comp138864_c0_seq4,358,36.0335,0.53796624,7,39,,5.00E-07,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp138864_c0_seq9,438,34.4749,0.31537521,9,11,,2.00E-07,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp138865_c1_seq1,358,44.6927,0.33740865,4,35,,1.00E-11,Q9UDV7,Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1),Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1),GO:0003677; GO:0045892; GO:0005634; GO:0006351; GO:0008270,"DNA binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent; zinc ion binding",PF12417;PF01352;PF00096;PF13912;,,,,,,,,,ZN282_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138865_c2_seq1,231,39.3939,0.78455577,0,21,,1.00E-14,O14771,Zinc finger protein 213 (Putative transcription factor CR53) (Zinc finger protein with KRAB and SCAN domains 21),Zinc finger protein 213 (Putative transcription factor CR53) (Zinc finger protein with KRAB and SCAN domains 21),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;,,,,,,,,,ZN213_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp138865_c3_seq2,1451,42.4535,0.58434943,2,79,,2.00E-11,Q6P9G9,Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19),Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZN449_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp138865_c3_seq4,1298,43.9137,0.54617662,13,56,,5.00E-08,Q9HBE1,"POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)","POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)",GO:0003677; GO:0030217; GO:0003682; GO:0008584; GO:0046872; GO:0045892; GO:0005634; GO:0045893; GO:0007283; GO:0006351,"DNA binding; T cell differentiation; chromatin binding; male gonad development; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,PATZ1_HUMAN,Homo sapiens (Human),"male gonad development [GO:0008584]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; T cell differentiation [GO:0030217]" comp138865_c3_seq6,1667,40.4319,0.58790378,33,296,,1.00E-10,Q66K89,Transcription factor E4F1 (EC 6.3.2.-) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F) (p120E4F) (p50E4F),Transcription factor E4F1 (EC 6.3.2.-) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F) (p120E4F) (p50E4F),GO:0006260; GO:0035497; GO:0051301; GO:0008283; GO:0005737; GO:0009790; GO:0016874; GO:0046872; GO:0007067; GO:0071850; GO:0019048; GO:0000122; GO:0005654; GO:0016567; GO:0010564; GO:0040008; GO:0009794; GO:0003700; GO:0005819; GO:0003713; GO:0003714; GO:0006351,"DNA replication; cAMP response element binding; cell division; cell proliferation; cytoplasm; embryo development; ligase activity; metal ion binding; mitosis; mitotic cell cycle arrest; modulation by virus of host morphology or physiology; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein ubiquitination; regulation of cell cycle process; regulation of growth; regulation of mitotic cell cycle, embryonic; sequence-specific DNA binding transcription factor activity; spindle; transcription coactivator activity; transcription corepressor activity; transcription, DNA-dependent",PF13912;,,,,,,,,,E4F1_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; cell proliferation [GO:0008283]; DNA replication [GO:0006260]; mitotic cell cycle arrest [GO:0071850]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle, embryonic [GO:0009794]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp138867_c1_seq1,2958,42.0892,0.70150277,43,32,,1.00E-118,O94985,Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)],Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)],GO:0000139; GO:0005509; GO:0030054; GO:0042995; GO:0005789; GO:0005576; GO:0007156; GO:0016021; GO:0005634; GO:0045211,Golgi membrane; calcium ion binding; cell junction; cell projection; endoplasmic reticulum membrane; extracellular region; homophilic cell adhesion; integral to membrane; nucleus; postsynaptic membrane,PF00028;,,,,,,,,,CSTN1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell growth [GO:0001558] comp138867_c1_seq2,2601,41.6763,0.68835989,2,0,,,,,,,,,9.00E-35,CHOYP_CLSTN1.1.1,3.00E-13,ruditapes_c25003,,,,,,, comp138871_c0_seq3,653,48.392,0.42120616,0,0,,,,,,,,,2.00E-93,CHOYP_LOC100371299.1.1,,,,,,,,, comp138871_c1_seq1,2588,45.9042,0.46345649,150,120,,6.00E-168,A0JP70,WD repeat-containing protein 90,WD repeat-containing protein 90,,,PF05018;PF00400;,3.00E-160,CHOYP_LOC100371299.1.1,,,,,,,WDR90_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp138872_c0_seq1,2208,38.7681,0.53226595,33,140,,0,Q9H7Z6,"Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)","Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)",GO:0071339; GO:0072487; GO:0043984; GO:0043981; GO:0043982; GO:0004402; GO:0000776; GO:0046872; GO:0035064; GO:0030099; GO:0045892; GO:0045893; GO:0008134; GO:0006351,"MLL1 complex; MSL complex; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity; kinetochore; metal ion binding; methylated histone residue binding; myeloid cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF01853;PF11717;,0,CHOYP_KAT8.1.1,,,,,,,KAT8_HUMAN,Homo sapiens (Human),"histone acetylation [GO:0016573]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of autophagy [GO:0010506]; transcription, DNA-templated [GO:0006351]" comp138872_c0_seq2,1770,37.8531,0.36412977,3,0,,3.00E-175,Q9H7Z6,"Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)","Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)",GO:0071339; GO:0072487; GO:0043984; GO:0043981; GO:0043982; GO:0004402; GO:0000776; GO:0046872; GO:0035064; GO:0030099; GO:0045892; GO:0045893; GO:0008134; GO:0006351,"MLL1 complex; MSL complex; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity; kinetochore; metal ion binding; methylated histone residue binding; myeloid cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF01853;PF11717;,2.00E-46,CHOYP_KAT6B.1.2,,,,,,,KAT8_HUMAN,Homo sapiens (Human),"histone acetylation [GO:0016573]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of autophagy [GO:0010506]; transcription, DNA-templated [GO:0006351]" comp138873_c1_seq1,1030,41.7476,0.60441693,3119,4797,,3.00E-124,Q54NE6,Probable phosphoglycerate mutase (EC 3.1.3.13) (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM) (dPGM),Probable phosphoglycerate mutase (EC 3.1.3.13) (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM) (dPGM),GO:0004083; GO:0004082; GO:0005829; GO:0006094; GO:0006096; GO:0045335; GO:0004619,bisphosphoglycerate 2-phosphatase activity; bisphosphoglycerate mutase activity; cytosol; gluconeogenesis; glycolysis; phagocytic vesicle; phosphoglycerate mutase activity,PF00300;,9.00E-112,CHOYP_GPMA.1.1,3.00E-141,ruditapes2_c616,,,,,PGAM_DICDI,Dictyostelium discoideum (Slime mold),gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of pentose-phosphate shunt [GO:0043456] comp138882_c0_seq1,1224,43.8725,0.30783212,42,29,,,,,,,,,2.00E-114,CHOYP_PSME4.1.1,,,,,,,,, comp138882_c1_seq1,2123,43.6175,0.40806352,4,0,,0,Q5SSW2,Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO),Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO),GO:0006281; GO:0005829; GO:0070577; GO:0007275; GO:0016607; GO:0005634; GO:0016504; GO:0010499; GO:0035093; GO:1990111,"DNA repair; cytosol; histone acetyl-lysine binding; multicellular organismal development; nuclear speck; nucleus; peptidase activator activity; proteasomal ubiquitin-independent protein catabolic process; spermatogenesis, exchange of chromosomal proteins; spermatoproteasome complex",PF16507;PF11919;,6.00E-99,CHOYP_PSME4.1.1,,,,,,,PSME4_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; multicellular organism development [GO:0007275]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]" comp138882_c1_seq3,2139,43.6653,0.40421081,0,0,,0,Q5SSW2,Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO),Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO),GO:0006281; GO:0005829; GO:0070577; GO:0007275; GO:0016607; GO:0005634; GO:0016504; GO:0010499; GO:0035093; GO:1990111,"DNA repair; cytosol; histone acetyl-lysine binding; multicellular organismal development; nuclear speck; nucleus; peptidase activator activity; proteasomal ubiquitin-independent protein catabolic process; spermatogenesis, exchange of chromosomal proteins; spermatoproteasome complex",PF16507;PF11919;,,,,,,,,,PSME4_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; multicellular organism development [GO:0007275]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]" comp138884_c0_seq1,1400,33.5714,0.20301048,0,0,,2.00E-10,Q9C0F0,Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3),Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13919;PF05066;PF13922;,,,,,,,,,ASXL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138884_c0_seq4,1399,33.8813,0.19948714,11,11,,5.00E-11,Q9C0F0,Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3),Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13919;PF05066;PF13922;,9.00E-19,CHOYP_LOC584010.1.1,,,,,,,ASXL3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138886_c0_seq1,1290,41.3178,0.62135877,419,2569,,3.00E-90,Q4V7D6,Putative GTP cyclohydrolase 1 type 2 Nif3l1 (EC 3.5.4.16) (GTP cyclohydrolase I) (NIF3-like protein 1),NIF3-like protein 1,GO:0003934; GO:0005737; GO:0045893,"GTP cyclohydrolase I activity; cytoplasm; positive regulation of transcription, DNA-dependent",PF01784;,,,,,,,,,NIF3L_RAT,Rattus norvegicus (Rat),"negative regulation of nucleic acid-templated transcription [GO:1903507]; neuron differentiation [GO:0030182]; positive regulation of transcription, DNA-templated [GO:0045893]" comp138890_c1_seq2,2488,40.4743,0.42302166,39,126,,,,,,,,,2.00E-150,CHOYP_MCRS1.1.1,,,,,,,,, comp138890_c1_seq3,2544,39.5833,0.44276277,9,56,,5.00E-173,Q96EZ8,Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2),Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2),GO:0006310; GO:0006281; GO:0031011; GO:0071339; GO:0005737; GO:0043984; GO:0043981; GO:0043982; GO:0000123; GO:0006355; GO:0006351,"DNA recombination; DNA repair; Ino80 complex; MLL1 complex; cytoplasm; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00498;PF13325;,2.00E-150,CHOYP_MCRS1.1.1,,,,,,,MCRS1_HUMAN,Homo sapiens (Human),"cellular protein modification process [GO:0006464]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of protein localization to nucleolus [GO:1904751]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138894_c2_seq1,853,44.197,0.71835578,6,155,,4.00E-30,Q9UKP4,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS7_HUMAN,Homo sapiens (Human),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; protein O-linked fucosylation [GO:0036066]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp138895_c0_seq3,910,27.6923,0.40258887,30,160,,,,,,,,,,,3.00E-13,ruditapes_c19639,,,,,,, comp138898_c0_seq1,1982,43.0878,0.69395379,2901,17000,,0,Q63639,Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)),Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)),GO:0004028; GO:0042904; GO:0009952; GO:0001568; GO:0048738; GO:0071300; GO:0005829; GO:0009855; GO:0031076; GO:0048566; GO:0035115; GO:0060324; GO:0003007; GO:0030902; GO:0001822; GO:0001889; GO:0030324; GO:0007494; GO:0016331; GO:0008285; GO:0014032; GO:0021915; GO:0030182; GO:0005634; GO:0031016; GO:0048471; GO:0021983; GO:0043065; GO:0008284; GO:0010628; GO:0009954; GO:0001936; GO:0034097; GO:0032355; GO:0033189; GO:0016918; GO:0001758; GO:0042574; GO:0002138; GO:0048384; GO:0042572; GO:0035799,3-chloroallyl aldehyde dehydrogenase activity; 9-cis-retinoic acid biosynthetic process; anterior/posterior pattern specification; blood vessel development; cardiac muscle tissue development; cellular response to retinoic acid; cytosol; determination of bilateral symmetry; embryonic camera-type eye development; embryonic digestive tract development; embryonic forelimb morphogenesis; face development; heart morphogenesis; hindbrain development; kidney development; liver development; lung development; midgut development; morphogenesis of embryonic epithelium; negative regulation of cell proliferation; neural crest cell development; neural tube development; neuron differentiation; nucleus; pancreas development; perinuclear region of cytoplasm; pituitary gland development; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of gene expression; proximal/distal pattern formation; regulation of endothelial cell proliferation; response to cytokine stimulus; response to estradiol stimulus; response to vitamin A; retinal binding; retinal dehydrogenase activity; retinal metabolic process; retinoic acid biosynthetic process; retinoic acid receptor signaling pathway; retinol metabolic process; ureter maturation,PF00171;,7.00E-136,CHOYP_NEMVEDRAFT_V1G181421.1.1,2.00E-77,ruditapes2_c1038,,,,,AL1A2_RAT,Rattus norvegicus (Rat),9-cis-retinoic acid biosynthetic process [GO:0042904]; anterior/posterior pattern specification [GO:0009952]; blood vessel development [GO:0001568]; cardiac muscle tissue development [GO:0048738]; cellular response to retinoic acid [GO:0071300]; determination of bilateral symmetry [GO:0009855]; embryonic camera-type eye development [GO:0031076]; embryonic digestive tract development [GO:0048566]; embryonic forelimb morphogenesis [GO:0035115]; face development [GO:0060324]; heart morphogenesis [GO:0003007]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; liver development [GO:0001889]; lung development [GO:0030324]; midgut development [GO:0007494]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of cell proliferation [GO:0008285]; neural crest cell development [GO:0014032]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; pituitary gland development [GO:0021983]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; proximal/distal pattern formation [GO:0009954]; regulation of endothelial cell proliferation [GO:0001936]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to vitamin A [GO:0033189]; retinal metabolic process [GO:0042574]; retinoic acid biosynthetic process [GO:0002138]; retinoic acid metabolic process [GO:0042573]; retinoic acid receptor signaling pathway [GO:0048384]; retinol metabolic process [GO:0042572]; ureter maturation [GO:0035799] comp138902_c0_seq1,2417,42.4079,0.44751887,333,2099,,0,Q7ZXX9,Ribosome biogenesis protein bop1-B (Block of proliferation 1 protein B),Ribosome biogenesis protein bop1-B (Block of proliferation 1 protein B),GO:0070545; GO:0000463; GO:0005654; GO:0051726,"PeBoW complex; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleoplasm; regulation of cell cycle",PF08145;PF00400;,2.00E-131,CHOYP_BOP1.1.1,,,,,,,BOP1B_XENLA,Xenopus laevis (African clawed frog),"maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; regulation of cell cycle [GO:0051726]" comp138905_c4_seq2,1111,38.6139,0.4354337,72,18,,1.00E-17,Q6P047,Uncharacterized protein C8orf74,Uncharacterized protein C8orf74,,,PF14769;,,,,,,,,,CH074_HUMAN,Homo sapiens (Human), comp138905_c4_seq3,1124,38.79,0.45023732,12,0,,2.00E-20,Q2NL11,Uncharacterized protein C8orf74 homolog,Uncharacterized protein C8orf74 homolog,,,PF14769;,,,,,,,,,CH074_BOVIN,Bos taurus (Bovine), comp138908_c1_seq1,608,44.2434,0.47610135,17,84,,1.00E-105,Q96MW5,Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8),Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8),GO:0000139; GO:0017119; GO:0015031,Golgi membrane; Golgi transport complex; protein transport,PF04124;,1.00E-62,CHOYP_COG8.1.1,,,,,,,COG8_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp138912_c0_seq2,435,40.4598,0.50776666,2,55,,,,,,,,,,,3.00E-29,ruditapes_c29520,,,,,,, comp138913_c4_seq4,1497,43.0862,1.00908471,940,1,male>female,9.00E-07,Q0VD59,E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII),E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII),GO:0002495; GO:0030659; GO:0031901; GO:0005768; GO:0016021; GO:0005765; GO:0005764; GO:0045347; GO:0000209; GO:0004842; GO:0008270,antigen processing and presentation of peptide antigen via MHC class II; cytoplasmic vesicle membrane; early endosome membrane; endosome; integral to membrane; lysosomal membrane; lysosome; negative regulation of MHC class II biosynthetic process; protein polyubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,MARH8_BOVIN,Bos taurus (Bovine),adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209] comp138915_c0_seq4,1838,43.6344,1.22675705,702,0,,2.00E-32,O42282,Photoreceptor outer segment membrane glycoprotein 2 (CRDS2),Photoreceptor outer segment membrane glycoprotein 2 (CRDS2),GO:0016021; GO:0007601,integral to membrane; visual perception,PF00335;,,,,,,,,,RDS2_CHICK,Gallus gallus (Chicken),visual perception [GO:0007601] comp138917_c0_seq1,1220,40.1639,0.53015182,0,0,,3.00E-11,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp138917_c0_seq11,274,48.5401,0.31307339,39,7,,2.00E-16,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,1.00E-32,CHOYP_LOC575277.2.2,,,,,,,CL063_HUMAN,, comp138917_c0_seq20,239,41.0042,0.30000525,15,0,,,,,,,,,2.00E-31,CHOYP_LOC575277.2.2,,,,,,,,, comp138917_c0_seq22,1043,39.2138,0.52727321,0,0,,2.00E-11,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp138920_c0_seq1,3109,44.6767,0.64146697,258,9,,4.00E-25,Q8ND61,Uncharacterized protein C3orf20,Uncharacterized protein C3orf20,GO:0005737; GO:0016021,cytoplasm; integral to membrane,PF14977;,,,,,,,,,CC020_HUMAN,Homo sapiens (Human), comp138920_c0_seq2,1498,45.5274,0.62185759,44,0,,4.00E-26,Q8ND61,Uncharacterized protein C3orf20,Uncharacterized protein C3orf20,GO:0005737; GO:0016021,cytoplasm; integral to membrane,PF14977;,8.00E-64,CHOYP_BRAFLDRAFT_118221.2.2,,,,,,,CC020_HUMAN,Homo sapiens (Human), comp138921_c0_seq1,1729,44.5922,0.46820676,56,800,,,,,,,,,4.00E-100,CHOYP_NEMVEDRAFT_V1G185623.1.1,,,,,,,,, comp138921_c0_seq2,3375,37.363,0.49810235,774,2488,,8.00E-82,Q54TR1,Counting factor associated protein D,Counting factor associated protein D,GO:0031410; GO:0005576; GO:0008285; GO:0031288,cytoplasmic vesicle; extracellular region; negative regulation of cell proliferation; sorocarp morphogenesis,PF08246;PF00112;,,,,,,,,,CFAD_DICDI,Dictyostelium discoideum (Slime mold),negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; sorocarp morphogenesis [GO:0031288]; sporulation resulting in formation of a cellular spore [GO:0030435] comp138921_c0_seq3,2632,37.9179,0.46908208,380,3820,,2.00E-64,P25782,Digestive cysteine proteinase 2 (EC 3.4.22.-),Digestive cysteine proteinase 2 (EC 3.4.22.-),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF08246;PF00112;,6.00E-100,CHOYP_NEMVEDRAFT_V1G185623.1.1,,,,,,,CYSP2_HOMAM,Homarus americanus (American lobster), comp138922_c0_seq1,1457,38.2979,0.4137933,134,318,,,,,,,,,,,6.00E-38,ruditapes_c15743,,,,,,, comp138923_c0_seq1,2441,38.9185,0.43302486,207,1573,,4.00E-11,A8MQ27,E3 ubiquitin-protein ligase NEURL1B (EC 6.3.2.-) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3),E3 ubiquitin-protein ligase NEURL1B (EC 6.3.2.-) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3),GO:0007219; GO:0005737; GO:0016874; GO:0016567; GO:0008270,Notch signaling pathway; cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,PF07177;,1.00E-44,CHOYP_LOC100533294.3.3,5.00E-35,ruditapes_c29234,,,,,NEU1B_HUMAN,Homo sapiens (Human),Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]; ubiquitin-dependent endocytosis [GO:0070086] comp138924_c0_seq1,1854,46.3862,0.53299123,14,5,,,,,,,,,5.00E-156,CHOYP_SMG7.1.1,,,,,,,,, comp138924_c0_seq2,2045,46.1125,0.50923173,89,22,,7.00E-119,Q92540,Protein SMG7 (EST1-like protein C) (SMG-7 homolog) (hSMG-7),Protein SMG7 (EST1-like protein C) (SMG-7 homolog) (hSMG-7),GO:0005829; GO:0010467; GO:0045111; GO:0006406; GO:0000184; GO:0005634; GO:0051721; GO:0035303,"cytosol; gene expression; intermediate filament cytoskeleton; mRNA export from nucleus; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; protein phosphatase 2A binding; regulation of dephosphorylation",PF10374;PF10373;,,,,,,,,,SMG7_HUMAN,Homo sapiens (Human),"mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]" comp138927_c0_seq1,2425,32.9485,0.3650637,9,94,,,,,,,,,2.00E-11,CHOYP_TVAG_168010.8.45,,,,,,,,, comp138927_c0_seq4,2411,33.0568,0.34953885,2,7,,,,,,,,,2.00E-11,CHOYP_TVAG_168010.8.45,4.00E-11,ruditapes_c17037,,,,,,, comp138931_c0_seq1,1820,44.2308,1.03679806,129,632,,4.00E-135,Q95NN1,"Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)","Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)",GO:0020037; GO:0046872; GO:0004833; GO:0019441,"heme binding; metal ion binding; tryptophan 2,3-dioxygenase activity; tryptophan catabolic process to kynurenine",PF03301;,1.00E-61,CHOYP_BRAFLDRAFT_210874.1.1,,,,,,,T23O_TRICA,Tribolium castaneum (Red flour beetle),tryptophan catabolic process to kynurenine [GO:0019441] comp138933_c0_seq10,1634,44.186,0.54007257,0,0,,3.00E-41,A6NFN3,RNA binding protein fox-1 homolog 3 (Fox-1 homolog C),RNA binding protein fox-1 homolog 3 (Fox-1 homolog C),GO:0003677; GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0043025; GO:0000166; GO:0005634; GO:0000381,"DNA binding; RNA binding; RNA splicing; cytoplasm; mRNA processing; neuronal cell body; nucleotide binding; nucleus; regulation of alternative mRNA splicing, via spliceosome",PF12414;PF00076;,,,,,,,,,RFOX3_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" comp138933_c0_seq11,1318,42.261,0.5799905,0,0,,1.00E-41,O43251,RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity),RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity),GO:0003723; GO:0016070; GO:0008380; GO:0005737; GO:0048813; GO:0030520; GO:0003729; GO:0006397; GO:0045892; GO:0050885; GO:0000166; GO:0005634; GO:0021942; GO:0000381; GO:0042127; GO:0010724; GO:0003714; GO:0008134,"RNA binding; RNA metabolic process; RNA splicing; cytoplasm; dendrite morphogenesis; intracellular estrogen receptor signaling pathway; mRNA binding; mRNA processing; negative regulation of transcription, DNA-dependent; neuromuscular process controlling balance; nucleotide binding; nucleus; radial glia guided migration of Purkinje cell; regulation of alternative mRNA splicing, via spliceosome; regulation of cell proliferation; regulation of definitive erythrocyte differentiation; transcription corepressor activity; transcription factor binding",PF12414;PF00076;,5.00E-47,CHOYP_RFOX2.1.2,,,,,,,RFOX2_HUMAN,Homo sapiens (Human),"dendrite morphogenesis [GO:0048813]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell proliferation [GO:0042127]; regulation of definitive erythrocyte differentiation [GO:0010724]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]" comp138933_c0_seq12,2004,42.1657,0.55180194,0,0,,6.00E-42,Q95KI0,RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0043484,RNA binding; RNA splicing; cytoplasm; mRNA processing; nucleotide binding; nucleus; regulation of RNA splicing,PF12414;PF00076;,1.00E-38,CHOYP_ISCW_ISCW013123.1.1,,,,,,,RFOX1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] comp138933_c0_seq2,1980,42.0707,0.54911486,0,0,,5.00E-42,Q95KI0,RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0043484,RNA binding; RNA splicing; cytoplasm; mRNA processing; nucleotide binding; nucleus; regulation of RNA splicing,PF12414;PF00076;,,,,,,,,,RFOX1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] comp138933_c0_seq3,1658,44.2702,0.54299187,0,0,,9.00E-42,Q9JJ43,RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0050885; GO:0005654; GO:0000166; GO:0043484,RNA binding; RNA splicing; cytoplasm; mRNA processing; neuromuscular process controlling balance; nucleoplasm; nucleotide binding; regulation of RNA splicing,PF12414;PF00076;,,,,,,,,,RFOX1_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA splicing [GO:0008380]" comp138933_c0_seq4,1340,42.2388,0.58815822,0,11,,1.00E-08,P62997,"Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)","Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)",GO:0003729; GO:0000398; GO:0000166; GO:0005634; GO:0048026; GO:0000381; GO:0000302,"mRNA binding; mRNA splicing, via spliceosome; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome; response to reactive oxygen species",PF00076;,2.00E-38,CHOYP_RBFOX3.1.1,,,,,,,TRA2B_RAT,Rattus norvegicus (Rat),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to reactive oxygen species [GO:0000302]" comp138933_c0_seq5,1621,43.6767,0.57052887,0,0,,9.00E-42,Q9JJ43,RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0050885; GO:0005654; GO:0000166; GO:0043484,RNA binding; RNA splicing; cytoplasm; mRNA processing; neuromuscular process controlling balance; nucleoplasm; nucleotide binding; regulation of RNA splicing,PF12414;PF00076;,,,,,,,,,RFOX1_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA splicing [GO:0008380]" comp138933_c0_seq7,1960,42.398,0.55781392,0,0,,3.00E-39,Q7ZT82,RNA binding protein fox-1 homolog 1-like (Ataxin 2-binding protein 1-like) (Fox-1 homolog-like protein 1),RNA binding protein fox-1 homolog 1-like (Ataxin 2-binding protein 1-like) (Fox-1 homolog-like protein 1),GO:0003723; GO:0008380; GO:0048739; GO:0006397; GO:0000166; GO:0005634; GO:0043484; GO:0048741,RNA binding; RNA splicing; cardiac muscle fiber development; mRNA processing; nucleotide binding; nucleus; regulation of RNA splicing; skeletal muscle fiber development,PF12414;PF00076;,,,,,,,,,RFX1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cardiac muscle fiber development [GO:0048739]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; skeletal muscle fiber development [GO:0048741]" comp138933_c0_seq8,1597,43.5817,0.56796432,0,0,,2.00E-42,Q5NVN8,RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0043484,RNA binding; RNA splicing; cytoplasm; mRNA processing; nucleotide binding; nucleus; regulation of RNA splicing,PF12414;PF00076;,6.00E-47,CHOYP_RFOX2.1.2,,,,,,,RFOX1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] comp138933_c0_seq9,1936,42.3037,0.55524649,0,0,,2.00E-41,A6QPR6,RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (RNA-binding motif protein 9) (RNA-binding protein 9),RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (RNA-binding motif protein 9) (RNA-binding protein 9),GO:0003723; GO:0008380; GO:0005737; GO:0030520; GO:0006397; GO:0045892; GO:0000166; GO:0005634; GO:0043484; GO:0003714; GO:0008134,"RNA binding; RNA splicing; cytoplasm; intracellular estrogen receptor signaling pathway; mRNA processing; negative regulation of transcription, DNA-dependent; nucleotide binding; nucleus; regulation of RNA splicing; transcription corepressor activity; transcription factor binding",PF12414;PF00076;,7.00E-47,CHOYP_RFOX2.1.2,,,,,,,RFOX2_BOVIN,Bos taurus (Bovine),"intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" comp138933_c1_seq1,1015,39.9015,0.84803932,0,4,,2.00E-13,Q61670,H2.0-like homeobox protein (Homeobox protein HLX1),H2.0-like homeobox protein (Homeobox protein HLX1),GO:0030154; GO:0048557; GO:0048484; GO:0001889; GO:0045629; GO:0005634; GO:0045627; GO:0008284; GO:0046622; GO:0003700; GO:0007519; GO:0000976; GO:0006351,"cell differentiation; embryonic digestive tract morphogenesis; enteric nervous system development; liver development; negative regulation of T-helper 2 cell differentiation; nucleus; positive regulation of T-helper 1 cell differentiation; positive regulation of cell proliferation; positive regulation of organ growth; sequence-specific DNA binding transcription factor activity; skeletal muscle tissue development; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00046;,,,,,,,,,HLX_MOUSE,Mus musculus (Mouse),"animal organ development [GO:0048513]; cell differentiation [GO:0030154]; embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp138933_c1_seq2,1742,40.2411,1.00907567,0,159,,8.00E-17,O55144,T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein),T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein),GO:0007417; GO:0045665; GO:0048665; GO:0001764; GO:0005634; GO:0002087; GO:0007585; GO:0043565; GO:0003700,central nervous system development; negative regulation of neuron differentiation; neuron fate specification; neuron migration; nucleus; regulation of respiratory gaseous exchange by neurological system process; respiratory gaseous exchange; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;,,,,,,,,,TLX3_MOUSE,Mus musculus (Mouse),"cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; negative regulation of neuron differentiation [GO:0045665]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuron migration [GO:0001764]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; regulation of transcription, DNA-templated [GO:0006355]; respiratory gaseous exchange [GO:0007585]" comp138935_c0_seq2,2525,46.2178,0.74215112,8,0,,2.00E-172,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,0,CHOYP_TRIADDRAFT_55768.2.2,9.00E-121,ruditapes2_c863,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp138935_c0_seq4,2546,46.4258,0.74381582,13,0,,1.00E-171,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,8.00E-16,CHOYP_CRE_13958.1.1,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp138936_c0_seq2,2377,38.4939,0.47006478,177,80,,2.00E-117,Q5R5C9,Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-),Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF03435;,1.00E-44,CHOYP_SCPDL.1.1,,,,,,,SCPDL_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp138937_c0_seq1,732,42.623,0.39586032,37,6,,1.00E-36,Q7XPJ0,Kinesin-like calmodulin-binding protein homolog,Kinesin-like calmodulin-binding protein homolog,GO:0005524; GO:0005871; GO:0003777; GO:0007018; GO:0016491,ATP binding; kinesin complex; microtubule motor activity; microtubule-based movement; oxidoreductase activity,PF00373;PF09379;PF00225;PF00784;,5.00E-44,CHOYP_LOC373208.1.1,,,,,,,KCBP_ORYSJ,Oryza sativa subsp. japonica (Rice),microtubule-based movement [GO:0007018] comp138937_c2_seq1,1408,45.4545,0.32131952,101,78,,,,,,,,,1.00E-11,CHOYP_BRAFLDRAFT_127731.1.1,,,,,,,,, comp138937_c3_seq1,1002,39.1218,0.18314874,0,5,,1.00E-68,Q9UBL3,Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein),Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein),GO:0071339; GO:0048188; GO:0030097; GO:0051568; GO:0046872; GO:0008284; GO:0045944; GO:0006355; GO:0006974; GO:0043627; GO:0006366; GO:0044212,"MLL1 complex; Set1C/COMPASS complex; hemopoiesis; histone H3-K4 methylation; metal ion binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to DNA damage stimulus; response to estrogen stimulus; transcription from RNA polymerase II promoter; transcription regulatory region DNA binding",PF00622;,,,6.00E-42,ruditapes_c22781,,,,,ASH2L_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; cellular response to DNA damage stimulus [GO:0006974]; hemopoiesis [GO:0030097]; histone H3-K4 methylation [GO:0051568]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase II promoter [GO:0006366]" comp138937_c3_seq3,2031,42.2944,0.2655371,50,167,,6.00E-180,Q91X20,Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein),Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein),GO:0071339; GO:0048188; GO:0051568; GO:0042800; GO:0046872; GO:0008284; GO:0045944; GO:0006974; GO:0043627; GO:0044212; GO:0006351,"MLL1 complex; Set1C/COMPASS complex; histone H3-K4 methylation; histone methyltransferase activity (H3-K4 specific); metal ion binding; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; response to estrogen stimulus; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00622;,2.00E-85,CHOYP_AAK1.1.1,,,,,,,ASH2L_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; chromatin-mediated maintenance of transcription [GO:0048096]; histone H3-K4 methylation [GO:0051568]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]" comp138939_c1_seq2,2411,43.7578,0.45342287,2,0,,3.00E-88,Q9BY12,S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291),S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291),GO:0005783; GO:0046872; GO:0005634,endoplasmic reticulum; metal ion binding; nucleus,PF16501;,,,,,,,,,SCAPE_HUMAN,Homo sapiens (Human), comp138939_c1_seq3,3077,44.4914,0.44184915,77,33,,3.00E-133,Q9BY12,S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291),S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291),GO:0005783; GO:0046872; GO:0005634,endoplasmic reticulum; metal ion binding; nucleus,PF16501;,0,CHOYP_SCAPER.1.1,,,,,,,SCAPE_HUMAN,Homo sapiens (Human), comp138939_c2_seq2,707,47.5248,0.40136135,0,0,,,,,,,,,1.00E-70,CHOYP_SCAPER.1.1,,,,,,,,, comp138941_c0_seq1,2697,45.5321,0.50149238,174,276,,2.00E-71,Q6ZPY2,Protein SMG5 (EST1-like protein B) (SMG-5 homolog),Protein SMG5 (EST1-like protein B) (SMG-5 homolog),GO:0005737; GO:0000184; GO:0005634; GO:0051721; GO:0035303,"cytoplasm; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; protein phosphatase 2A binding; regulation of dephosphorylation",PF10374;PF10373;PF13638;,2.00E-30,CHOYP_SMG5.1.1,,,,,,,SMG5_MOUSE,Mus musculus (Mouse),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]" comp138953_c0_seq2,1333,33.1583,0.60867796,66,543,,5.00E-23,Q2PFU1,Huntingtin-interacting protein K (Huntingtin yeast partner K),Huntingtin-interacting protein K (Huntingtin yeast partner K),GO:0005737; GO:0005634,cytoplasm; nucleus,,7.00E-20,CHOYP_BRAFLDRAFT_119906.1.1,2.00E-56,ruditapes_c7210,,,,,HYPK_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp138953_c1_seq1,2495,37.5551,0.54479603,151,30727,female>male,3.00E-142,Q8MPM1,Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2),Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2),GO:0051693; GO:0005737; GO:0005856,actin filament capping; cytoplasm; cytoskeleton,PF00626;,1.00E-76,CHOYP_LOC100642024.1.2,,,,,,,GELS2_LUMTE,Lumbricus terrestris (Common earthworm),actin filament capping [GO:0051693] comp138954_c0_seq2,2522,46.2331,0.45285175,2,7,,7.00E-19,Q5RC32,Nuclear protein MDM1,Nuclear protein MDM1,GO:0005634,nucleus,PF15501;,,,,,,,,,MDM1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of centriole replication [GO:0046600] comp138956_c0_seq3,2244,40.3298,0.52290556,0,0,,1.00E-57,Q8R5C8,Zinc finger MYND domain-containing protein 11,Zinc finger MYND domain-containing protein 11,GO:0003677; GO:0016568; GO:0005694; GO:0005737; GO:0043124; GO:0046329; GO:2001237; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; chromatin modification; chromosome; cytoplasm; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of JNK cascade; negative regulation of extrinsic apoptotic signaling pathway; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00855;,2.00E-61,CHOYP_ZMY11.1.1,,,,,,,ZMY11_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of JNK cascade [GO:0046329]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp138956_c0_seq4,1540,38.961,0.48566046,0,0,,,,,,,,,4.00E-11,CHOYP_PKCB1.1.1,,,,,,,,, comp138962_c0_seq2,1805,41.8283,0.82427562,114,253,,1.00E-05,H2A0N4,Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)],Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)],GO:0008061; GO:0006030; GO:0005576,chitin binding; chitin metabolic process; extracellular region,PF01607;PF00092;,,,,,,,,,PIF_PINMG,Pinctada margaritifera (Black-lipped pearl oyster),chitin metabolic process [GO:0006030] comp138963_c0_seq2,2065,32.2034,0.4858979,105,5,,,,,,,,,7.00E-54,CHOYP_LOC100373985.1.1,,,,,,,,, comp138964_c0_seq1,1976,42.8138,0.47897581,3650,26634,,0,P80317,T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta-1),T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta-1),GO:0005524; GO:0001669; GO:0007339; GO:0044297; GO:0005832; GO:0006457; GO:0002199,ATP binding; acrosomal vesicle; binding of sperm to zona pellucida; cell body; chaperonin-containing T-complex; protein folding; zona pellucida receptor complex,PF00118;,0,CHOYP_LOC594665.1.1,0,ruditapes2_c1338,,,,,TCPZ_MOUSE,Mus musculus (Mouse),binding of sperm to zona pellucida [GO:0007339]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; toxin transport [GO:1901998] comp138967_c0_seq1,2183,40.1741,0.81303695,72,497,,2.00E-38,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,,,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp138968_c0_seq1,1782,39.5062,0.61879761,25,223,,9.00E-10,Q6NX45,Zinc finger protein 774,Zinc finger protein 774,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN774_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138968_c0_seq2,1553,39.6008,0.5423455,43,275,,1.00E-10,Q91VN1,Zinc finger protein 24 (Hypomyelinated CNS protein) (Zinc finger protein 191) (Zfp-191) (Zinc finger protein ZF-12),Zinc finger protein 24 (Hypomyelinated CNS protein) (Zinc finger protein 191) (Zinc finger protein ZF-12),GO:0046872; GO:0042552; GO:0045892; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"metal ion binding; myelination; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZNF24_MOUSE,Mus musculus (Mouse),"myelination [GO:0042552]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp138968_c0_seq4,1448,40.6768,0.56805211,23,112,,9.00E-13,A7KBS4,Zinc finger and SCAN domain containing protein 4D,Zinc finger and SCAN domain containing protein 4D,GO:0003677; GO:0046872; GO:0000784; GO:0003700; GO:0010833; GO:0006351,"DNA binding; metal ion binding; nuclear chromosome, telomeric region; sequence-specific DNA binding transcription factor activity; telomere maintenance via telomere lengthening; transcription, DNA-dependent",PF02023;,,,,,,,,,ZSC4D_MOUSE,Mus musculus (Mouse),"telomere maintenance via telomere lengthening [GO:0010833]; transcription, DNA-templated [GO:0006351]" comp138968_c0_seq5,1645,40.9726,0.50738059,17,117,,7.00E-12,Q9BYN7,Zinc finger protein 341,Zinc finger protein 341,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN341_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138969_c1_seq1,2253,31.5135,0.49614802,63,222,,1.00E-13,Q06205,FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 4 (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005528; GO:0000183; GO:0000412; GO:0005527; GO:0000415; GO:0005730; GO:0006334; GO:0005634; GO:0003755; GO:0006457; GO:0034401,FK506 binding; chromatin silencing at rDNA; histone peptidyl-prolyl isomerization; macrolide binding; negative regulation of histone H3-K36 methylation; nucleolus; nucleosome assembly; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; regulation of transcription by chromatin organization,PF00254;,3.00E-33,CHOYP_LOC100563952.1.1,,,,,,,FKBP4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),chaperone-mediated protein folding [GO:0061077]; histone peptidyl-prolyl isomerization [GO:0000412]; negative regulation of histone H3-K36 methylation [GO:0000415]; nucleosome assembly [GO:0006334] comp138969_c1_seq3,2266,31.5093,0.51252745,32,615,,3.00E-18,Q66H94,Peptidyl-prolyl cis-trans isomerase FKBP9 (PPIase FKBP9) (EC 5.2.1.8) (FK506-binding protein 9) (FKBP-9) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP9 (PPIase FKBP9) (EC 5.2.1.8) (FK506-binding protein 9) (FKBP-9) (Rotamase),GO:0005528; GO:0005509; GO:0005783; GO:0005788; GO:0016020; GO:0003755; GO:0006457,FK506 binding; calcium ion binding; endoplasmic reticulum; endoplasmic reticulum lumen; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF13202;PF00254;,,,,,,,,,FKBP9_RAT,Rattus norvegicus (Rat),chaperone-mediated protein folding [GO:0061077] comp138969_c1_seq5,1863,32.0451,0.54463446,0,0,,4.00E-52,Q32PA9,Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (FK506-binding protein 2) (FKBP-2) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (FK506-binding protein 2) (FKBP-2) (Rotamase),GO:0005528; GO:0005789; GO:0016020; GO:0003755; GO:0006457,FK506 binding; endoplasmic reticulum membrane; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,,,,,,,,,FKBP2_BOVIN,Bos taurus (Bovine),chaperone-mediated protein folding [GO:0061077] comp138975_c1_seq1,1390,45.9712,0.71211174,158,271,,,,,,,,,1.00E-16,CHOYP_LOC100376003.1.1,,,,,,,,, comp138975_c2_seq1,1835,39.2916,0.67205627,290,565,,4.00E-19,Q5U4Q0,WW domain-containing adapter protein with coiled-coil,WW domain-containing adapter protein with coiled-coil,GO:0044783; GO:0000993; GO:0003682; GO:0071894; GO:0010390; GO:0005634; GO:0045893; GO:0006351,"G1 DNA damage checkpoint; RNA polymerase II core binding; chromatin binding; histone H2B conserved C-terminal lysine ubiquitination; histone monoubiquitination; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00397;,,,,,,,,,WAC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cellular response to DNA damage stimulus [GO:0006974]; G1 DNA damage checkpoint [GO:0044783]; histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone monoubiquitination [GO:0010390]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp138979_c0_seq1,874,38.3295,0.53227723,25,208,,9.00E-49,Q91W78,U6 snRNA phosphodiesterase (EC 3.1.4.-),U6 snRNA phosphodiesterase (EC 3.1.4.-),GO:0000175; GO:0008380; GO:0034477; GO:0006397; GO:0005634,3'-5'-exoribonuclease activity; RNA splicing; U6 snRNA 3'-end processing; mRNA processing; nucleus,PF09749;,2.00E-25,CHOYP_USB1.1.1,,,,,,,USB1_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; U6 snRNA 3'-end processing [GO:0034477] comp138980_c0_seq1,1290,44.8062,0.4609752,47,718,,9.00E-116,Q6NY77,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase)","4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase)",GO:0008700; GO:0009436; GO:0005739,4-hydroxy-2-oxoglutarate aldolase activity; glyoxylate catabolic process; mitochondrion,PF00701;,3.00E-36,CHOYP_LOC579934.1.1,,,,,,,HOGA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glyoxylate catabolic process [GO:0009436] comp138981_c0_seq1,678,45.7227,0.57297285,0,0,,,,,,,,,1.00E-133,CHOYP_LOC100645380.1.1,,,,,,,,, comp138981_c0_seq2,1388,44.2363,0.55792498,41,253,,0,Q9DBG7,Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha),Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha),GO:0005525; GO:0003924; GO:0006614; GO:0016020; GO:0005047; GO:0005785,GTP binding; GTPase activity; SRP-dependent cotranslational protein targeting to membrane; membrane; signal recognition particle binding; signal recognition particle receptor complex,PF04086;PF00448;PF02881;,0,CHOYP_LOC100645380.1.1,,,,,,,SRPR_MOUSE,Mus musculus (Mouse),SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp138981_c0_seq4,443,38.8262,0.50772128,0,4,,5.00E-19,P08240,Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha),Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha),GO:0005525; GO:0003924; GO:0006614; GO:0006987; GO:0016021; GO:0005047; GO:0005785; GO:0006412,GTP binding; GTPase activity; SRP-dependent cotranslational protein targeting to membrane; activation of signaling protein activity involved in unfolded protein response; integral to membrane; signal recognition particle binding; signal recognition particle receptor complex; translation,PF04086;PF00448;PF02881;,,,,,,,,,SRPR_HUMAN,Homo sapiens (Human),cotranslational protein targeting to membrane [GO:0006613]; IRE1-mediated unfolded protein response [GO:0036498]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp138982_c0_seq1,2415,41.1594,0.31524399,163,2092,,6.00E-63,B2GV47,Uncharacterized protein CXorf57 homolog,Uncharacterized protein CXorf57 homolog,,,,,,,,,,,,CX057_RAT,Rattus norvegicus (Rat), comp138984_c1_seq1,932,46.6738,0.61140306,3,0,,2.00E-08,Q6ZMW2,Zinc finger protein 782,Zinc finger protein 782,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN782_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq10,954,44.8637,0.45926559,10,43,,2.00E-11,P51502,Zinc finger protein 80,Zinc finger protein 80,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZNF80_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq12,1808,36.9469,0.50964709,5,5,,1.00E-11,Q9UJQ4,Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4),Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4),GO:0003677; GO:0005737; GO:0030326; GO:0000792; GO:0001833; GO:0046872; GO:0000122; GO:0001843; GO:0005634; GO:0045944; GO:0043234; GO:0019827; GO:0006351; GO:0003281,"DNA binding; cytoplasm; embryonic limb morphogenesis; heterochromatin; inner cell mass cell proliferation; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein complex; stem cell maintenance; transcription, DNA-dependent; ventricular septum development",PF00096;,,,,,,,,,SALL4_HUMAN,Homo sapiens (Human),"embryonic limb morphogenesis [GO:0030326]; inner cell mass cell proliferation [GO:0001833]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281]" comp138984_c1_seq14,1112,44.7842,0.52112673,0,0,,5.00E-09,P08154,Early growth response protein 1 (EGR-1) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor Zif268) (Zinc finger protein Krox-24),Early growth response protein 1 (EGR-1) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor Zif268) (Zinc finger protein Krox-24),GO:0030509; GO:0001077; GO:0000979; GO:0030217; GO:0071236; GO:0071320; GO:0035690; GO:0071372; GO:0071480; GO:0071363; GO:0071504; GO:0071455; GO:0071456; GO:0032869; GO:0071317; GO:0071260; GO:0071506; GO:0071383; GO:0007623; GO:0005737; GO:0003690; GO:0072110; GO:0070498; GO:0007611; GO:0060291; GO:0046872; GO:0043066; GO:0090090; GO:0000122; GO:0005634; GO:0048709; GO:0072303; GO:0043525; GO:0048169; GO:0033233; GO:0001975; GO:0034465; GO:0042220; GO:0051602; GO:0045471; GO:0009749; GO:0071873; GO:0031667; GO:0035914,BMP signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation; cellular response to antibiotic; cellular response to cAMP; cellular response to drug; cellular response to follicle-stimulating hormone stimulus; cellular response to gamma radiation; cellular response to growth factor stimulus; cellular response to heparin; cellular response to hyperoxia; cellular response to hypoxia; cellular response to insulin stimulus; cellular response to isoquinoline alkaloid; cellular response to mechanical stimulus; cellular response to mycophenolic acid; cellular response to steroid hormone stimulus; circadian rhythm; cytoplasm; double-stranded DNA binding; glomerular mesangial cell proliferation; interleukin-1-mediated signaling pathway; learning or memory; long-term synaptic potentiation; metal ion binding; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; oligodendrocyte differentiation; positive regulation of glomerular metanephric mesangial cell proliferation; positive regulation of neuron apoptotic process; regulation of long-term neuronal synaptic plasticity; regulation of protein sumoylation; response to amphetamine; response to carbon monoxide; response to cocaine; response to electrical stimulus; response to ethanol; response to glucose stimulus; response to norepinephrine stimulus; response to nutrient levels; skeletal muscle cell differentiation,PF11914;PF11928;,,,,,,,,,EGR1_RAT,Rattus norvegicus (Rat),"cellular response to antibiotic [GO:0071236]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heparin [GO:0071504]; cellular response to hyperoxia [GO:0071455]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to isoquinoline alkaloid [GO:0071317]; cellular response to mechanical stimulus [GO:0071260]; cellular response to mycophenolic acid [GO:0071506]; cellular response to steroid hormone stimulus [GO:0071383]; circadian rhythm [GO:0007623]; glomerular mesangial cell proliferation [GO:0072110]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell death [GO:0010942]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular metanephric mesangial cell proliferation [GO:0072303]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; response to amphetamine [GO:0001975]; response to carbon monoxide [GO:0034465]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to follicle-stimulating hormone [GO:0032354]; response to gonadotropin [GO:0034698]; response to norepinephrine [GO:0071873]; response to nutrient levels [GO:0031667]; wound healing [GO:0042060]" comp138984_c1_seq15,478,39.749,0.42763272,0,0,,2.00E-10,Q5R5U3,Zinc finger protein 271,Zinc finger protein 271,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN271_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq16,1237,36.055,0.40424516,0,0,,6.00E-10,Q14591,Zinc finger protein 271 (CT-ZFP48) (Epstein-Barr virus-induced zinc finger protein) (EBV-induced zinc finger protein) (ZNF-EB) (Zinc finger protein HZF7) (Zinc finger protein ZNFphex133) (Zinc finger protein dp) (ZNF-dp),,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN271_HUMAN,, comp138984_c1_seq2,1008,46.0317,0.52493549,0,0,,3.00E-12,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq3,1767,40.5772,0.46896567,0,0,,7.00E-08,Q9NQZ8,Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71),Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZNF71_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq4,582,38.488,0.42492837,0,0,,5.00E-11,Q14591,Zinc finger protein 271 (CT-ZFP48) (Epstein-Barr virus-induced zinc finger protein) (EBV-induced zinc finger protein) (ZNF-EB) (Zinc finger protein HZF7) (Zinc finger protein ZNFphex133) (Zinc finger protein dp) (ZNF-dp),,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN271_HUMAN,, comp138984_c1_seq5,2070,37.9227,0.57196415,1,7,,8.00E-11,B7ZRU9,MDS1 and EVI1 complex locus protein EVI1-A (Ecotropic virus integration site 1 protein homolog-A) (Evi-1) (xEvi-1),MDS1 and EVI1 complex locus protein EVI1-A (Ecotropic virus integration site 1 protein homolog-A) (Evi-1) (xEvi-1),GO:0003677; GO:0046872; GO:0000122; GO:0016607; GO:0039013; GO:0039022; GO:0072196; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nuclear speck; pronephric distal tubule morphogenesis; pronephric duct development; proximal/distal pattern formation involved in pronephric nephron development; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,EVI1A_XENLA,Xenopus laevis (African clawed frog),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; pronephros development [GO:0048793]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq6,1786,40.6495,0.48970473,1,6,,8.00E-12,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138984_c1_seq8,1163,36.6294,0.39161182,0,0,,2.00E-09,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp138988_c1_seq3,2831,45.1077,0.67440957,0,0,,9.00E-09,O94986,Centrosomal protein of 152 kDa (Cep152),Centrosomal protein of 152 kDa (Cep152),GO:0000086; GO:0005813; GO:0051298; GO:0005829; GO:0005634,G2/M transition of mitotic cell cycle; centrosome; centrosome duplication; cytosol; nucleus,,,,,,,,,,CE152_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; de novo centriole assembly [GO:0098535]; G2/M transition of mitotic cell cycle [GO:0000086] comp138999_c3_seq1,1475,41.0169,0.62983092,0,0,,5.00E-10,B1WBU4,Zinc finger and BTB domain-containing protein 8A,Zinc finger and BTB domain-containing protein 8A,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT8A_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139000_c1_seq2,854,33.3724,0.38617939,69,167,,,,,,,,,,,4.00E-12,ruditapes_c7836,,,,,,, comp139000_c1_seq3,1468,41.485,0.56260148,56,207,,1.00E-156,Q9XSJ0,Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5),Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5),GO:0006310; GO:0006281; GO:0031011; GO:0005829; GO:0004866; GO:0048853; GO:0021670; GO:0030901; GO:0005634; GO:0008242; GO:0070628; GO:0000502; GO:0016579; GO:0061136; GO:0006355; GO:0006351; GO:0004221; GO:0006511; GO:0004843,"DNA recombination; DNA repair; Ino80 complex; cytosol; endopeptidase inhibitor activity; forebrain morphogenesis; lateral ventricle development; midbrain development; nucleus; omega peptidase activity; proteasome binding; proteasome complex; protein deubiquitination; regulation of proteasomal protein catabolic process; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity",PF01088;,3.00E-133,CHOYP_UCHL5.2.2,,,,,,,UCHL5_BOVIN,Bos taurus (Bovine),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; forebrain morphogenesis [GO:0048853]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; protein deubiquitination [GO:0016579]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp139000_c1_seq5,1563,41.2028,0.53226785,24,95,,3.00E-156,Q9XSJ0,Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5),Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5),GO:0006310; GO:0006281; GO:0031011; GO:0005829; GO:0004866; GO:0048853; GO:0021670; GO:0030901; GO:0005634; GO:0008242; GO:0070628; GO:0000502; GO:0016579; GO:0061136; GO:0006355; GO:0006351; GO:0004221; GO:0006511; GO:0004843,"DNA recombination; DNA repair; Ino80 complex; cytosol; endopeptidase inhibitor activity; forebrain morphogenesis; lateral ventricle development; midbrain development; nucleus; omega peptidase activity; proteasome binding; proteasome complex; protein deubiquitination; regulation of proteasomal protein catabolic process; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity",PF01088;,,,,,,,,,UCHL5_BOVIN,Bos taurus (Bovine),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; forebrain morphogenesis [GO:0048853]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; protein deubiquitination [GO:0016579]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp139004_c0_seq2,1964,36.7108,0.65617009,315,238,,2.00E-53,P91929,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)",GO:0005524; GO:0005811; GO:0005759; GO:0005739; GO:0006139; GO:0055114; GO:0016773; GO:0070469,"ATP binding; lipid particle; mitochondrial matrix; mitochondrion; nucleobase-containing compound metabolic process; oxidation-reduction process; phosphotransferase activity, alcohol group as acceptor; respiratory chain",PF01712;,,,,,,,,,NDUAA_DROME,Drosophila melanogaster (Fruit fly),"mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; regulation of glucose metabolic process [GO:0010906]" comp139007_c0_seq1,2211,41.5197,0.48472876,359,1286,,2.00E-148,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,0,CHOYP_AAEL_AAEL009387.1.1,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp139008_c1_seq1,1568,39.9872,1.07257466,4,37,,7.00E-31,Q5UQG7,Putative serine/threonine-protein kinase/receptor R818 (EC 2.7.11.1),Putative serine/threonine-protein kinase/receptor R818 (EC 2.7.11.1),GO:0005524; GO:0009190; GO:0016021; GO:0035556; GO:0016849; GO:0004674,ATP binding; cyclic nucleotide biosynthetic process; integral to membrane; intracellular signal transduction; phosphorus-oxygen lyase activity; protein serine/threonine kinase activity,PF00211;PF12849;PF07714;,,,,,,,,,YR818_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),cyclic nucleotide biosynthetic process [GO:0009190]; intracellular signal transduction [GO:0035556] comp139008_c1_seq2,1752,39.0982,1.04769338,28,102,,2.00E-38,Q05609,Serine/threonine-protein kinase CTR1 (EC 2.7.11.1),Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1),GO:0005524; GO:0071281; GO:0005789; GO:0009873; GO:0009686; GO:0010105; GO:0046777; GO:0004674; GO:0004712; GO:2000069; GO:2000035; GO:0048510; GO:0009723; GO:0009750; GO:0009744; GO:0010182,ATP binding; cellular response to iron ion; endoplasmic reticulum membrane; ethylene mediated signaling pathway; gibberellin biosynthetic process; negative regulation of ethylene mediated signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; regulation of post-embryonic root development; regulation of stem cell division; regulation of timing of transition from vegetative to reproductive phase; response to ethylene stimulus; response to fructose stimulus; response to sucrose stimulus; sugar mediated signaling pathway,PF07714;,,,,,,,,,CTR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cellular response to iron ion [GO:0071281]; ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] comp139009_c0_seq1,2380,32.6471,0.49467873,4143,29254,,1.00E-69,P23438,Translocon-associated protein subunit beta (TRAP-beta) (Glycoprotein 25H) (gp25H) (Signal sequence receptor subunit beta) (SSR-beta),Translocon-associated protein subunit beta (TRAP-beta) (Glycoprotein 25H) (gp25H) (Signal sequence receptor subunit beta) (SSR-beta),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,,7.00E-61,CHOYP_SSRB.1.2,,,,,,,SSRB_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp139011_c0_seq6,608,27.1382,0.45624936,13,6,,,,,,,,,,,3.00E-11,ruditapes_c31302,,,,,,, comp139011_c0_seq7,232,44.3966,0.45155878,0,6,,9.00E-25,Q03168,Lysosomal aspartic protease (EC 3.4.23.-),Lysosomal aspartic protease (EC 3.4.23.-),GO:0004190; GO:0005764; GO:0006508,aspartic-type endopeptidase activity; lysosome; proteolysis,PF00026;,5.00E-19,CHOYP_LOC655494.1.3,3.00E-26,ruditapes_c5247,,,,,ASPP_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp139012_c2_seq2,278,42.446,0.72889187,0,105,,3.00E-16,Q8IXL7,Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-),Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-),GO:0005783; GO:0005739; GO:0033743; GO:0030091; GO:0008270,endoplasmic reticulum; mitochondrion; peptide-methionine (R)-S-oxide reductase activity; protein repair; zinc ion binding,PF01641;,,,,,,,,,MSRB3_HUMAN,Homo sapiens (Human),protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp139012_c2_seq3,957,40.8568,0.87756587,10,61,,4.00E-31,Q6UXX5,Inter-alpha-trypsin inhibitor heavy chain H6 (Inter-alpha-trypsin inhibitor heavy chain H5-like protein) (Inter-alpha inhibitor H5-like protein),Inter-alpha-trypsin inhibitor heavy chain H6 (Inter-alpha-trypsin inhibitor heavy chain H5-like protein) (Inter-alpha inhibitor H5-like protein),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH6_HUMAN,Homo sapiens (Human),hyaluronan metabolic process [GO:0030212] comp139013_c6_seq1,1398,37.3391,0.67871721,1231,4390,,9.00E-26,Q8MS27,"39S ribosomal protein L35, mitochondrial (L35mt) (MRP-L35)","39S ribosomal protein L35, mitochondrial (L35mt) (MRP-L35)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF01632;,,,2.00E-18,ruditapes2_c2710,,,,,RM35_DROME,Drosophila melanogaster (Fruit fly),epithelium development [GO:0060429]; germarium-derived egg chamber formation [GO:0007293]; mitochondrial translation [GO:0032543] comp139014_c0_seq1,2651,41.6447,0.40494875,194,1700,,3.00E-145,Q13823,Nucleolar GTP-binding protein 2 (Autoantigen NGP-1),Nucleolar GTP-binding protein 2 (Autoantigen NGP-1),GO:0005525; GO:0003924; GO:0005730; GO:0042254,GTP binding; GTPase activity; nucleolus; ribosome biogenesis,PF01926;PF08153;,0,CHOYP_NOG2.1.1,,,,,,,NOG2_HUMAN,Homo sapiens (Human),ribosome biogenesis [GO:0042254] comp139014_c0_seq2,1818,43.3993,0.42067543,40,229,,0,Q13823,Nucleolar GTP-binding protein 2 (Autoantigen NGP-1),Nucleolar GTP-binding protein 2 (Autoantigen NGP-1),GO:0005525; GO:0003924; GO:0005730; GO:0042254,GTP binding; GTPase activity; nucleolus; ribosome biogenesis,PF01926;PF08153;,0,CHOYP_NOG2.1.1,,,,,,,NOG2_HUMAN,Homo sapiens (Human),ribosome biogenesis [GO:0042254] comp139016_c0_seq2,642,45.3271,0.54816842,0,0,,4.00E-58,Q6P7W0,Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6),Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6),GO:0016929; GO:0003676; GO:0005634; GO:0016926; GO:0016925; GO:0006508; GO:0090234; GO:0090169; GO:0008270,SUMO-specific protease activity; nucleic acid binding; nucleus; protein desumoylation; protein sumoylation; proteolysis; regulation of kinetochore assembly; regulation of spindle assembly; zinc ion binding,PF02902;,,,,,,,,,SENP6_MOUSE,Mus musculus (Mouse),protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169] comp139016_c0_seq3,1932,44.8758,0.59746352,0,0,,,,,,,,,3.00E-26,CHOYP_SENP6.1.1,,,,,,,,, comp139016_c0_seq5,1910,44.9738,0.60221695,3,0,,4.00E-53,Q9GZR1,Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6),Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6),GO:0016929; GO:0005737; GO:0005634; GO:0016926; GO:0016925; GO:0006508; GO:0090234; GO:0090169,SUMO-specific protease activity; cytoplasm; nucleus; protein desumoylation; protein sumoylation; proteolysis; regulation of kinetochore assembly; regulation of spindle assembly,PF02902;,3.00E-26,CHOYP_SENP6.1.1,,,,,,,SENP6_HUMAN,Homo sapiens (Human),protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169] comp139016_c1_seq1,720,41.9444,0.85618321,7,51,,2.00E-26,O16025,Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],GO:0047677; GO:0019369; GO:0004096; GO:0005737; GO:0020037; GO:0047987; GO:0005506; GO:0016020; GO:0031408,arachidonate 8(R)-lipoxygenase activity; arachidonic acid metabolic process; catalase activity; cytoplasm; heme binding; hydroperoxide dehydratase activity; iron ion binding; membrane; oxylipin biosynthetic process,PF00305;PF01477;,,,,,,,,,AOSL_PLEHO,Plexaura homomalla (Black sea rod),arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408] comp139019_c0_seq10,1612,37.2829,0.55470158,0,0,,3.00E-38,P09988,Histone H3.1/H3.2,Histone H3.1/H3.2,GO:0003677; GO:0006281; GO:0031934; GO:0031618; GO:0000788; GO:0006334; GO:0006974; GO:0031933,DNA binding; DNA repair; mating-type region heterochromatin; nuclear centromeric heterochromatin; nuclear nucleosome; nucleosome assembly; response to DNA damage stimulus; telomeric heterochromatin,PF00125;,2.00E-14,CHOYP_H33.3.5,,,,,,,H31_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; nucleosome assembly [GO:0006334] comp139019_c0_seq7,1648,36.9539,0.5525783,0,0,,4.00E-38,P09988,Histone H3.1/H3.2,Histone H3.1/H3.2,GO:0003677; GO:0006281; GO:0031934; GO:0031618; GO:0000788; GO:0006334; GO:0006974; GO:0031933,DNA binding; DNA repair; mating-type region heterochromatin; nuclear centromeric heterochromatin; nuclear nucleosome; nucleosome assembly; response to DNA damage stimulus; telomeric heterochromatin,PF00125;,2.00E-14,CHOYP_H33.3.5,5.00E-14,ruditapes_lrc32855,,,,,H31_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; nucleosome assembly [GO:0006334] comp139019_c0_seq8,1590,38.4277,0.68253995,2,3,,5.00E-37,P90543,Histone H3,Histone H3,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;,,,,,,,,,H3_EUPCR,Euplotes crassus, comp139024_c1_seq1,1585,40.1893,0.42214134,0,0,,1.00E-103,Q9NWW7,Uncharacterized protein C2orf42,Uncharacterized protein C2orf42,,,PF14952;,4.00E-93,CHOYP_LOC100370611.1.1,,,,,,,CB042_HUMAN,Homo sapiens (Human), comp139025_c1_seq2,544,42.0956,0.47242082,4,0,,3.00E-33,O35550,Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha),Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha),GO:0005096; GO:0006915; GO:0005769; GO:0030139; GO:0006897; GO:0005768; GO:0043547; GO:0015031; GO:0055037,GTPase activator activity; apoptotic process; early endosome; endocytic vesicle; endocytosis; endosome; positive regulation of GTPase activity; protein transport; recycling endosome,PF09311;PF03528;,6.00E-16,CHOYP_LOC585032.2.2,,,,,,,RABE1_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp139025_c3_seq13,1877,41.1295,0.25854421,60,51,,3.00E-36,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139025_c3_seq5,1539,36.4522,1.05696682,0,0,,8.00E-26,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139025_c3_seq7,877,42.1893,0.33425379,0,0,,5.00E-11,Q9HCI6,Uncharacterized protein KIAA1586,E3 SUMO-protein ligase KIAA1586 (EC 6.3.2.-),GO:0003676,nucleic acid binding,,,,,,,,,,K1586_HUMAN,Homo sapiens (Human),protein sumoylation [GO:0016925] comp139025_c4_seq1,665,46.1654,0.50306699,32,38,,2.00E-07,O35551,Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha),Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha),GO:0005096; GO:0006915; GO:0005769; GO:0030139; GO:0006897; GO:0005768; GO:0043547; GO:0015031; GO:0055037,GTPase activator activity; apoptotic process; early endosome; endocytic vesicle; endocytosis; endosome; positive regulation of GTPase activity; protein transport; recycling endosome,PF09311;PF03528;,,,,,,,,,RABE1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp139026_c0_seq4,1580,38.9241,0.41832496,34,502,,4.00E-16,P26652,Metalloproteinase inhibitor 3 (21 kDa protein of extracellular matrix) (Tissue inhibitor of metalloproteinases 3) (TIMP-3),Metalloproteinase inhibitor 3 (21 kDa protein of extracellular matrix) (Tissue inhibitor of metalloproteinases 3) (TIMP-3),GO:0046872; GO:0008191; GO:0005578,metal ion binding; metalloendopeptidase inhibitor activity; proteinaceous extracellular matrix,PF00965;,,,,,,,,,TIMP3_CHICK,Gallus gallus (Chicken),negative regulation of catalytic activity [GO:0043086]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; response to organic substance [GO:0010033] comp139027_c1_seq1,3186,43.4401,0.41080093,65,100,,5.00E-163,Q9Y6J0,Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),GO:0016235; GO:0007166; GO:0016568; GO:0005737; GO:0005634; GO:0004864,aggresome; cell surface receptor signaling pathway; chromatin modification; cytoplasm; nucleus; protein phosphatase inhibitor activity,PF09047;,5.00E-26,CHOYP_CABIN1.1.1,,,,,,,CABIN_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823] comp139027_c1_seq2,1871,43.3993,0.35500753,7,3,,3.00E-37,Q9Y6J0,Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),GO:0016235; GO:0007166; GO:0016568; GO:0005737; GO:0005634; GO:0004864,aggresome; cell surface receptor signaling pathway; chromatin modification; cytoplasm; nucleus; protein phosphatase inhibitor activity,PF09047;,,,,,,,,,CABIN_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823] comp139028_c0_seq1,1884,38.482,0.54596637,45,86,,0,P31319,cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A),cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A),GO:0030552; GO:0005952; GO:0008603,cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity,PF00027;PF02197;,0,CHOYP_KAPR.2.3,,,,,,,KAPR_APLCA,Aplysia californica (California sea hare), comp139028_c0_seq2,2406,38.3624,0.45878997,22,110,,2.00E-66,Q8TF77,cAMP-dependent protein kinase regulatory subunit (PKA regulatory subunit),cAMP-dependent protein kinase regulatory subunit (PKA regulatory subunit),GO:0030552; GO:0005952; GO:0008603,cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity,PF00027;PF02197;,0,CHOYP_KAPR.1.3,,,,,,,KAPR_MUCCL,Mucor circinelloides f. lusitanicus (Mucor racemosus var. lusitanicus), comp139031_c0_seq1,1518,41.4361,0.48332123,46,591,,1.00E-103,Q9UJ70,N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase),N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase),GO:0005524; GO:0045127; GO:0006044; GO:0006051; GO:0019262; GO:0009384,ATP binding; N-acetylglucosamine kinase activity; N-acetylglucosamine metabolic process; N-acetylmannosamine metabolic process; N-acetylneuraminate catabolic process; N-acylmannosamine kinase activity,PF01869;,6.00E-28,CHOYP_LOC586039.1.1,,,,,,,NAGK_HUMAN,Homo sapiens (Human),N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp139032_c0_seq2,370,44.5946,0.43685924,0,0,,5.00E-15,Q3B7T8,Centrosomal protein of 44 kDa (Cep44),Centrosomal protein of 44 kDa (Cep44),GO:0005813; GO:0005737; GO:0030496; GO:0000922,centrosome; cytoplasm; midbody; spindle pole,PF15007;,5.00E-15,CHOYP_CEP44.2.2,,,,,,,CEP44_RAT,Rattus norvegicus (Rat), comp139034_c1_seq1,796,32.1608,0.4431067,76,328,,,,,,,,,5.00E-13,CHOYP_RN45S.5.5,,,,,,,,, comp139035_c0_seq1,2121,40.8298,1.0525796,445,3020,,7.00E-71,Q5R8L2,Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4),Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4),GO:0031519; GO:0016568; GO:0005737; GO:0030890; GO:0033092; GO:0051443; GO:0006355; GO:0006351; GO:0000151; GO:0008270,"PcG protein complex; chromatin modification; cytoplasm; positive regulation of B cell proliferation; positive regulation of immature T cell proliferation in thymus; positive regulation of ubiquitin-protein ligase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin ligase complex; zinc ion binding",PF16207;,2.00E-15,CHOYP_BMI1B.1.1,,,,,,,BMI1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"brain development [GO:0007420]; DNA methylation [GO:0006306]; embryonic skeletal system morphogenesis [GO:0048704]; histone acetylation [GO:0016573]; histone ubiquitination [GO:0016574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; rostrocaudal neural tube patterning [GO:0021903]; somatic stem cell division [GO:0048103]; transcription, DNA-templated [GO:0006351]" comp139038_c0_seq1,1920,42.5521,0.46273911,278,448,,0,Q9NXZ2,Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen),Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen),GO:0005524; GO:0004004; GO:0003723; GO:0005622,ATP binding; ATP-dependent RNA helicase activity; RNA binding; intracellular,PF00270;PF00271;PF00013;,2.00E-175,CHOYP_LOC101166328.1.1,,,,,,,DDX43_HUMAN,Homo sapiens (Human),RNA secondary structure unwinding [GO:0010501] comp139040_c3_seq1,1708,33.4309,0.46893179,87,1564,,4.00E-53,Q9GZQ3,COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG),COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG),GO:0005634,nucleus,PF07258;,9.00E-45,CHOYP_BRAFLDRAFT_132957.1.1,9.00E-62,ruditapes2_c2060,,,,,COMD5_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139042_c0_seq1,1911,40.921,0.46788373,80,202,,2.00E-06,Q3ECD0,"RNA pseudouridine synthase 2, chloroplastic (EC 5.4.99.-) (RNA pseudouridylate synthase 2) (RNA-uridine isomerase 2)","RNA pseudouridine synthase 2, chloroplastic (EC 5.4.99.-) (RNA pseudouridylate synthase 2) (RNA-uridine isomerase 2)",GO:0003723; GO:0009507; GO:0009982; GO:0001522,RNA binding; chloroplast; pseudouridine synthase activity; pseudouridine synthesis,PF00849;PF01479;,,,,,,,,,PUS2_ARATH,Arabidopsis thaliana (Mouse-ear cress),enzyme-directed rRNA pseudouridine synthesis [GO:0000455] comp139042_c0_seq2,1638,42.5519,0.47879195,5,12,,3.00E-107,Q149F1,RNA pseudouridylate synthase domain-containing protein 2,RNA pseudouridylate synthase domain-containing protein 2,GO:0003723; GO:0009982; GO:0001522,RNA binding; pseudouridine synthase activity; pseudouridine synthesis,PF00849;,,,,,,,,,RUSD2_MOUSE,Mus musculus (Mouse),tRNA pseudouridine synthesis [GO:0031119] comp139048_c1_seq1,878,41.5718,0.92387507,16,277,,1.00E-51,Q6GMG6,"Solute carrier family 52, riboflavin transporter, member 3-B (Riboflavin transporter 2-B) (RFT2-B)","Solute carrier family 52, riboflavin transporter, member 3-B (Riboflavin transporter 2-B) (RFT2-B)",GO:0016021; GO:0005886; GO:0006810,integral to membrane; plasma membrane; transport,PF06237;,,,,,,,,,S5A3B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139049_c0_seq1,1050,48.1905,0.29095584,2,0,,,,,,,,,1.00E-35,CHOYP_SC24B.2.2,,,,,,,,, comp139049_c2_seq1,3285,38.2648,0.51336391,86,165,,0,O95487,Protein transport protein Sec24B (SEC24-related protein B),Protein transport protein Sec24B (SEC24-related protein B),GO:0030127; GO:0048208; GO:0012507; GO:0000139; GO:0019886; GO:0002474; GO:0005829; GO:0005789; GO:0006886; GO:0048471; GO:0043687; GO:0018279; GO:0044281; GO:0005215; GO:0008270,COPII vesicle coat; COPII vesicle coating; ER to Golgi transport vesicle membrane; Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; cytosol; endoplasmic reticulum membrane; intracellular protein transport; perinuclear region of cytoplasm; post-translational protein modification; protein N-linked glycosylation via asparagine; small molecule metabolic process; transporter activity; zinc ion binding,PF00626;PF08033;PF04815;PF04811;PF04810;,,,,,,,,,SC24B_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; aorta morphogenesis [GO:0035909]; auditory receptor cell stereocilium organization [GO:0060088]; cochlear nucleus development [GO:0021747]; COPII vesicle coating [GO:0048208]; coronary artery morphogenesis [GO:0060982]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lung lobe morphogenesis [GO:0060463]; neural tube closure [GO:0001843]; outflow tract morphogenesis [GO:0003151]; pulmonary artery morphogenesis [GO:0061156]; regulation of cargo loading into COPII-coated vesicle [GO:1901301]; regulation of establishment of planar polarity involved in neural tube closure [GO:0090178]; vesicle-mediated transport [GO:0016192] comp139049_c2_seq3,1613,43.3974,0.5272315,3,0,,0,O95487,Protein transport protein Sec24B (SEC24-related protein B),Protein transport protein Sec24B (SEC24-related protein B),GO:0030127; GO:0048208; GO:0012507; GO:0000139; GO:0019886; GO:0002474; GO:0005829; GO:0005789; GO:0006886; GO:0048471; GO:0043687; GO:0018279; GO:0044281; GO:0005215; GO:0008270,COPII vesicle coat; COPII vesicle coating; ER to Golgi transport vesicle membrane; Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; cytosol; endoplasmic reticulum membrane; intracellular protein transport; perinuclear region of cytoplasm; post-translational protein modification; protein N-linked glycosylation via asparagine; small molecule metabolic process; transporter activity; zinc ion binding,PF00626;PF08033;PF04815;PF04811;PF04810;,0,CHOYP_SC24B.2.2,,,,,,,SC24B_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; aorta morphogenesis [GO:0035909]; auditory receptor cell stereocilium organization [GO:0060088]; cochlear nucleus development [GO:0021747]; COPII vesicle coating [GO:0048208]; coronary artery morphogenesis [GO:0060982]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lung lobe morphogenesis [GO:0060463]; neural tube closure [GO:0001843]; outflow tract morphogenesis [GO:0003151]; pulmonary artery morphogenesis [GO:0061156]; regulation of cargo loading into COPII-coated vesicle [GO:1901301]; regulation of establishment of planar polarity involved in neural tube closure [GO:0090178]; vesicle-mediated transport [GO:0016192] comp139051_c0_seq2,2433,38.1011,0.38817598,186,569,,2.00E-89,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,2.00E-61,CHOYP_BRAFLDRAFT_251779.1.2,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp139053_c0_seq1,3202,40.9744,0.97068082,2280,165,,2.00E-48,Q8C0R9,Leucine-rich repeat and death domain-containing protein 1,Leucine-rich repeat and death domain-containing protein 1,,,PF13855;,7.00E-31,CHOYP_BRAFLDRAFT_80919.1.1,1.00E-56,ruditapes_c8150,,,,,LRRD1_MOUSE,Mus musculus (Mouse), comp139054_c2_seq1,1190,35.6303,0.47700454,15,61,,1.00E-28,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139054_c2_seq2,1207,35.2941,0.45264419,11,49,,,,,,,,,9.00E-12,CHOYP_LOC100537368.2.2,,,,,,,,, comp139056_c2_seq2,1040,32.8846,0.61277757,2,17,,1.00E-08,Q13127,RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor),RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor),GO:0001078; GO:0060379; GO:0035690; GO:0071257; GO:0071385; GO:0003682; GO:0001046; GO:0005737; GO:0005829; GO:0070933; GO:0046872; GO:0043922; GO:0032348; GO:2000798; GO:0045955; GO:0008285; GO:2000065; GO:2000706; GO:0046676; GO:0050768; GO:0045665; GO:0015271; GO:0043065; GO:0043280; GO:0045893; GO:0017053,"RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cardiac muscle cell myoblast differentiation; cellular response to drug; cellular response to electrical stimulus; cellular response to glucocorticoid stimulus; chromatin binding; core promoter sequence-specific DNA binding; cytoplasm; cytosol; histone H4 deacetylation; metal ion binding; negative regulation by host of viral transcription; negative regulation of aldosterone biosynthetic process; negative regulation of amniotic stem cell differentiation; negative regulation of calcium ion-dependent exocytosis; negative regulation of cell proliferation; negative regulation of cortisol biosynthetic process; negative regulation of dense core granule biogenesis; negative regulation of insulin secretion; negative regulation of neurogenesis; negative regulation of neuron differentiation; outward rectifier potassium channel activity; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of transcription, DNA-dependent; transcriptional repressor complex",,,,,,,,,,REST_HUMAN,Homo sapiens (Human),"cardiac muscle cell myoblast differentiation [GO:0060379]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucocorticoid stimulus [GO:0071385]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of amniotic stem cell differentiation [GO:2000798]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of dense core granule biogenesis [GO:2000706]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of mesenchymal stem cell differentiation [GO:2000740]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]" comp139056_c2_seq4,1040,32.9808,0.64725448,0,3,,7.00E-07,Q96SQ5,Zinc finger protein 587,Zinc finger protein 587,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN587_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139057_c0_seq1,3213,43.1061,0.5897814,35,39,,,,,,,,,2.00E-36,CHOYP_BRAFLDRAFT_127500.1.1,,,,,,,,, comp139057_c0_seq2,3213,43.075,0.57721863,6,0,,8.00E-33,Q5ZL67,"Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)","Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)",GO:0005789; GO:0016021; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"endoplasmic reticulum membrane; integral to membrane; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF03131;,2.00E-36,CHOYP_BRAFLDRAFT_127500.1.1,,,,,,,NF2L1_CHICK,Gallus gallus (Chicken),"cellular response to oxidative stress [GO:0034599]; erythrocyte differentiation [GO:0030218]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]" comp139057_c0_seq3,752,40.1596,0.36405655,2,15,,1.00E-05,Q5NUA6,"Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2)","Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2)",GO:0005829; GO:0005634; GO:0043161; GO:0010499; GO:0016567; GO:0043565; GO:0003700; GO:0006351,"cytosol; nucleus; proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF03131;,,,,,,,,,NF2L2_BOVIN,Bos taurus (Bovine),"cellular response to fluid shear stress [GO:0071498]; cellular response to oxidative stress [GO:0034599]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp139057_c0_seq4,566,34.9823,0.92571718,42,41,,2.00E-09,Q5RA25,"Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)","Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)",GO:0005789; GO:0016021; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"endoplasmic reticulum membrane; integral to membrane; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF03131;,,,,,,,,,NF2L1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cellular response to oxidative stress [GO:0034599]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp139059_c1_seq3,1029,46.6472,0.47045227,0,0,,2.00E-16,A8XV95,Gelsolin-like protein 1,Gelsolin-like protein 1,GO:0051693; GO:0005737; GO:0005856,actin filament capping; cytoplasm; cytoskeleton,PF00626;,,,,,,,,,GELS1_CAEBR,Caenorhabditis briggsae,actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016] comp139059_c1_seq4,1014,47.2387,0.50160662,0,0,,5.00E-16,Q21253,Gelsolin-like protein 1,Gelsolin-like protein 1,GO:0015629; GO:0051015; GO:0051014; GO:0003785; GO:0051016; GO:0005546; GO:0055120,"actin cytoskeleton; actin filament binding; actin filament severing; actin monomer binding; barbed-end actin filament capping; phosphatidylinositol-4,5-bisphosphate binding; striated muscle dense body",PF00626;,,,,,,,,,GELS1_CAEEL,Caenorhabditis elegans,actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016] comp139059_c1_seq9,974,49.1786,0.57080318,0,0,,7.00E-100,Q29261,Villin-1,Villin-1,GO:0051015; GO:0032432; GO:0051693; GO:0030042; GO:0030041; GO:0051014; GO:0005509; GO:0071364; GO:0035729; GO:0043027; GO:0005737; GO:0060327; GO:0007173; GO:0032433; GO:0030027; GO:0035727; GO:0005902; GO:0005546; GO:0032233; GO:0010634; GO:0042803; GO:0051125; GO:0008360; GO:2000392; GO:0061041; GO:0009617; GO:0001726,"actin filament binding; actin filament bundle; actin filament capping; actin filament depolymerization; actin filament polymerization; actin filament severing; calcium ion binding; cellular response to epidermal growth factor stimulus; cellular response to hepatocyte growth factor stimulus; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; cytoplasmic actin-based contraction involved in cell motility; epidermal growth factor receptor signaling pathway; filopodium tip; lamellipodium; lysophosphatidic acid binding; microvillus; phosphatidylinositol-4,5-bisphosphate binding; positive regulation of actin filament bundle assembly; positive regulation of epithelial cell migration; protein homodimerization activity; regulation of actin nucleation; regulation of cell shape; regulation of lamellipodium morphogenesis; regulation of wound healing; response to bacterium; ruffle",PF00626;PF02209;,1.00E-91,CHOYP_LOC100369378.1.1,,,,,,,VILI_PIG,Sus scrofa (Pig),actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617] comp139062_c1_seq2,1606,43.5866,0.49508341,217,985,,0,P26443,"Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)","Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)",GO:0005524; GO:0005525; GO:0004352; GO:0004353; GO:0006541; GO:0007616; GO:0005743; GO:0005759; GO:0032024; GO:0010044; GO:0072350,ATP binding; GTP binding; glutamate dehydrogenase (NAD+) activity; glutamate dehydrogenase [NAD(P)+] activity; glutamine metabolic process; long-term memory; mitochondrial inner membrane; mitochondrial matrix; positive regulation of insulin secretion; response to aluminum ion; tricarboxylic acid metabolic process,PF00208;PF02812;,0,CHOYP_DHE4.1.1,,,,,,,DHE3_MOUSE,Mus musculus (Mouse),cerebellum development [GO:0021549]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; long-term memory [GO:0007616]; positive regulation of insulin secretion [GO:0032024]; response to aluminum ion [GO:0010044]; tricarboxylic acid metabolic process [GO:0072350] comp139065_c1_seq1,1659,41.6516,0.79469894,31,184,,3.00E-31,P55065,Phospholipid transfer protein (Lipid transfer protein II),Phospholipid transfer protein (Lipid transfer protein II),GO:0005576; GO:0008289; GO:0006869; GO:0030317; GO:0010189,extracellular region; lipid binding; lipid transport; sperm motility; vitamin E biosynthetic process,PF01273;PF02886;,,,,,,,,,PLTP_MOUSE,Mus musculus (Mouse),high-density lipoprotein particle remodeling [GO:0034375]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; positive regulation of cholesterol efflux [GO:0010875]; sperm motility [GO:0030317]; vitamin E biosynthetic process [GO:0010189] comp139065_c1_seq2,1319,44.2002,0.87128763,35,11,,3.00E-49,P18428,Lipopolysaccharide-binding protein (LBP),Lipopolysaccharide-binding protein (LBP),GO:0006953; GO:0009986; GO:0006968; GO:0071223; GO:0050829; GO:0050830; GO:0032490; GO:0005615; GO:0045087; GO:0002232; GO:0001530; GO:0015920; GO:0031663; GO:0070891; GO:0002281; GO:0044130; GO:0032720; GO:0008228; GO:0032722; GO:0032755; GO:0032757; GO:0043032; GO:0090023; GO:0060265; GO:0034145; GO:0042535; GO:0032760; GO:0005102; GO:0034142,acute-phase response; cell surface; cellular defense response; cellular response to lipoteichoic acid; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; detection of molecule of bacterial origin; extracellular space; innate immune response; leukocyte chemotaxis involved in inflammatory response; lipopolysaccharide binding; lipopolysaccharide transport; lipopolysaccharide-mediated signaling pathway; lipoteichoic acid binding; macrophage activation involved in immune response; negative regulation of growth of symbiont in host; negative regulation of tumor necrosis factor production; opsonization; positive regulation of chemokine production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of macrophage activation; positive regulation of neutrophil chemotaxis; positive regulation of respiratory burst involved in inflammatory response; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of tumor necrosis factor production; receptor binding; toll-like receptor 4 signaling pathway,PF01273;PF02886;,,,5.00E-13,ruditapes_c22422,,,,,LBP_HUMAN,Homo sapiens (Human),"acute-phase response [GO:0006953]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lipopolysaccharide transport [GO:0015920]; liver development [GO:0001889]; macrophage activation involved in immune response [GO:0002281]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of tumor necrosis factor production [GO:0032720]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of membrane permeability [GO:0090559]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142]" comp139066_c0_seq1,1502,45.1398,0.36454054,14,0,,1.00E-154,Q5RDS0,Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6),Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6),GO:0005789; GO:0016021; GO:0016042; GO:0004622; GO:0046470,endoplasmic reticulum membrane; integral to membrane; lipid catabolic process; lysophospholipase activity; phosphatidylcholine metabolic process,PF00027;PF01734;,9.00E-95,CHOYP_LOC100698638.1.1,,,,,,,PLPL6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470] comp139066_c0_seq2,2715,44.5672,0.41519362,361,22,,0,A2AJ88,Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-),Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (Neuropathy target esterase-related esterase) (NRE) (NTE-related esterase),GO:0005783; GO:0016787; GO:0016021; GO:0006629; GO:0005765; GO:0031966; GO:0031965,endoplasmic reticulum; hydrolase activity; integral to membrane; lipid metabolic process; lysosomal membrane; mitochondrial membrane; nuclear membrane,PF00027;PF01734;,1.00E-14,CHOYP_PNPLA7.1.1,,,,,,,PLPL7_MOUSE,Mus musculus (Mouse),developmental process [GO:0032502]; glycerophospholipid catabolic process [GO:0046475] comp139066_c0_seq4,1661,44.3107,0.35238541,26,11,,9.00E-154,Q5RDS0,Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6),Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6),GO:0005789; GO:0016021; GO:0016042; GO:0004622; GO:0046470,endoplasmic reticulum membrane; integral to membrane; lipid catabolic process; lysophospholipase activity; phosphatidylcholine metabolic process,PF00027;PF01734;,1.00E-94,CHOYP_LOC100698638.1.1,,,,,,,PLPL6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470] comp139067_c0_seq2,2761,40.8185,0.66450568,180,417,,6.00E-59,Q96T37,Putative RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15),Putative RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15),GO:0003723; GO:0019048; GO:0045638; GO:0000166; GO:0005634; GO:0001569; GO:0060674; GO:0007221; GO:0048536; GO:0060412,RNA binding; modulation by virus of host morphology or physiology; negative regulation of myeloid cell differentiation; nucleotide binding; nucleus; patterning of blood vessels; placenta blood vessel development; positive regulation of transcription of Notch receptor target; spleen development; ventricular septum morphogenesis,PF00076;PF07744;,5.00E-70,CHOYP_LOC663518.1.1,,,,,,,RBM15_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; negative regulation of myeloid cell differentiation [GO:0045638]; patterning of blood vessels [GO:0001569]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; spleen development [GO:0048536]; ventricular septum morphogenesis [GO:0060412]; viral process [GO:0016032]" comp139068_c0_seq1,1952,46.875,0.40677422,573,506,,0,P21872,Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)],Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)],GO:0006189; GO:0005524; GO:0005829; GO:0046872; GO:0032259; GO:0008168; GO:0004637; GO:0004641; GO:0004644; GO:0009113; GO:0006144,'de novo' IMP biosynthetic process; ATP binding; cytosol; metal ion binding; methylation; methyltransferase activity; phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity; phosphoribosylglycinamide formyltransferase activity; purine nucleobase biosynthetic process; purine nucleobase metabolic process,PF00586;PF02769;PF00551;PF01071;PF02843;PF02844;,7.00E-85,CHOYP_PUR2.1.1,,,,,,,PUR2_CHICK,Gallus gallus (Chicken),'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113] comp139070_c0_seq1,1054,39.0892,0.36099263,8,37,,1.00E-94,A7SKJ3,Diphthamide biosynthesis protein 2,Diphthamide biosynthesis protein 2,GO:0005737; GO:0017183,cytoplasm; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01866;,5.00E-33,CHOYP_BRAFLDRAFT_225211.1.1,5.00E-75,ruditapes_c10736,,,,,DPH2_NEMVE,Nematostella vectensis (Starlet sea anemone),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp139070_c0_seq2,1689,41.2078,0.44064106,59,202,,4.00E-148,A4QN59,Diphthamide biosynthesis protein 2 (DPH2 homolog),Diphthamide biosynthesis protein 2 (DPH2 homolog),GO:0005737; GO:0017183,cytoplasm; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01866;,,,,,,,,,DPH2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp139071_c1_seq5,2034,41.9371,0.6271188,4,64,,2.00E-59,Q3UCV8,Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby),Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby),GO:0060070; GO:0005737; GO:0045087; GO:0032088; GO:0050728; GO:0070431; GO:1990108; GO:0006508; GO:0002040; GO:0004843,canonical Wnt receptor signaling pathway; cytoplasm; innate immune response; negative regulation of NF-kappaB transcription factor activity; negative regulation of inflammatory response; nucleotide-binding oligomerization domain containing 2 signaling pathway; protein linear deubiquitination; proteolysis; sprouting angiogenesis; ubiquitin-specific protease activity,PF16218;,9.00E-21,CHOYP_LOC101065898.1.1,,,,,,,F105B_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; protein linear deubiquitination [GO:1990108]; sprouting angiogenesis [GO:0002040] comp139071_c1_seq6,2111,42.1127,0.69506061,0,0,,2.00E-59,Q3UCV8,Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby),Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby),GO:0060070; GO:0005737; GO:0045087; GO:0032088; GO:0050728; GO:0070431; GO:1990108; GO:0006508; GO:0002040; GO:0004843,canonical Wnt receptor signaling pathway; cytoplasm; innate immune response; negative regulation of NF-kappaB transcription factor activity; negative regulation of inflammatory response; nucleotide-binding oligomerization domain containing 2 signaling pathway; protein linear deubiquitination; proteolysis; sprouting angiogenesis; ubiquitin-specific protease activity,PF16218;,9.00E-21,CHOYP_LOC101065898.1.1,,,,,,,F105B_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; protein linear deubiquitination [GO:1990108]; sprouting angiogenesis [GO:0002040] comp139074_c0_seq2,1883,44.7159,0.47837508,67,397,,1.00E-106,P16554,Protein numb,Protein numb,GO:0005524; GO:0061382; GO:0005112; GO:0007219; GO:0055059; GO:0045180; GO:0035050; GO:0008347; GO:0042694; GO:0045746; GO:0007400; GO:0005634; GO:0061320; GO:0007422; GO:0045807; GO:0008104; GO:0009786; GO:0050767; GO:0007622; GO:0045035; GO:0016360; GO:0007419,ATP binding; Malpighian tubule tip cell differentiation; Notch binding; Notch signaling pathway; asymmetric neuroblast division; basal cortex; embryonic heart tube development; glial cell migration; muscle cell fate specification; negative regulation of Notch signaling pathway; neuroblast fate determination; nucleus; pericardial nephrocyte differentiation; peripheral nervous system development; positive regulation of endocytosis; protein localization; regulation of asymmetric cell division; regulation of neurogenesis; rhythmic behavior; sensory organ precursor cell division; sensory organ precursor cell fate determination; ventral cord development,PF06311;PF00640;,2.00E-116,CHOYP_NUMB.1.1,,,,,,,NUMB_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; centrosome localization [GO:0051642]; embryonic heart tube development [GO:0035050]; glial cell migration [GO:0008347]; heart development [GO:0007507]; Malpighian tubule tip cell differentiation [GO:0061382]; muscle cell fate specification [GO:0042694]; negative regulation of Notch signaling pathway [GO:0045746]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; Notch signaling pathway [GO:0007219]; pericardial nephrocyte differentiation [GO:0061320]; peripheral nervous system development [GO:0007422]; positive regulation of endocytosis [GO:0045807]; protein localization [GO:0008104]; regulation of asymmetric cell division [GO:0009786]; regulation of nervous system development [GO:0051960]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; rhythmic behavior [GO:0007622]; sensory organ precursor cell division [GO:0045035]; sensory organ precursor cell fate determination [GO:0016360]; ventral cord development [GO:0007419] comp139075_c0_seq3,1618,36.0321,0.40649226,0,46,,7.00E-36,Q8R331,Zinc finger HIT domain-containing protein 1,Zinc finger HIT domain-containing protein 1,GO:0003682; GO:0046872; GO:0070317; GO:0000122; GO:0005634; GO:0042129; GO:0031063,chromatin binding; metal ion binding; negative regulation of G0 to G1 transition; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of T cell proliferation; regulation of histone deacetylation,PF04438;,,,,,,,,,ZNHI1_MOUSE,Mus musculus (Mouse),histone exchange [GO:0043486]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of histone deacetylation [GO:0031063]; regulation of T cell proliferation [GO:0042129] comp139075_c0_seq5,1542,35.668,0.4144008,0,0,,6.00E-36,Q8R331,Zinc finger HIT domain-containing protein 1,Zinc finger HIT domain-containing protein 1,GO:0003682; GO:0046872; GO:0070317; GO:0000122; GO:0005634; GO:0042129; GO:0031063,chromatin binding; metal ion binding; negative regulation of G0 to G1 transition; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of T cell proliferation; regulation of histone deacetylation,PF04438;,2.00E-34,CHOYP_LOC100649205.1.1,2.00E-57,ruditapes_c8690,,,,,ZNHI1_MOUSE,Mus musculus (Mouse),histone exchange [GO:0043486]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of histone deacetylation [GO:0031063]; regulation of T cell proliferation [GO:0042129] comp139079_c1_seq2,1241,43.9162,0.50435898,35,57,,1.00E-73,Q9BXW9,Fanconi anemia group D2 protein (Protein FACD2),Fanconi anemia group D2 protein (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0005654; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; nucleoplasm; response to gamma radiation; synapsis,PF14631;,,,,,,,,,FACD2_HUMAN,Homo sapiens (Human),gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp139079_c1_seq3,840,43.9286,0.5484682,11,19,,3.00E-53,Q9BXW9,Fanconi anemia group D2 protein (Protein FACD2),Fanconi anemia group D2 protein (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0005654; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; nucleoplasm; response to gamma radiation; synapsis,PF14631;,1.00E-40,CHOYP_BRAFLDRAFT_216683.1.1,,,,,,,FACD2_HUMAN,Homo sapiens (Human),gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp139080_c0_seq2,4015,30.9838,0.53127897,206,591,,1.00E-44,Q5R5I4,Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin carrier protein L3) (Ubiquitin-protein ligase L3),Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (Ubiquitin carrier protein L3) (Ubiquitin-protein ligase L3),GO:0005524; GO:0008283; GO:0071385; GO:0005737; GO:0005634; GO:0070979; GO:0006355; GO:0003713; GO:0006351; GO:0004842,"ATP binding; cell proliferation; cellular response to glucocorticoid stimulus; cytoplasm; nucleus; protein K11-linked ubiquitination; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity",PF00179;,,,,,,,,,UB2L3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell cycle phase transition [GO:0044770]; cell proliferation [GO:0008283]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139086_c0_seq2,2650,43.5472,0.57497116,9,0,,7.00E-12,Q9Z0R6,Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B),Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B),GO:0005089; GO:0005509; GO:0005737; GO:0006897; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; calcium ion binding; cytoplasm; endocytosis; phospholipid binding; regulation of Rho protein signal transduction,PF00168;PF12763;PF16652;PF00621;PF00018;PF07653;PF14604;,,,,,,,,,ITSN2_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; positive regulation of dendrite extension [GO:1903861]; regulation of Rho protein signal transduction [GO:0035023] comp139086_c0_seq3,1712,45.0935,0.54196107,2,0,,4.00E-31,O54916,RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1),RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1),GO:0005509; GO:0005905; GO:0006898,calcium ion binding; coated pit; receptor-mediated endocytosis,PF12763;,4.00E-49,CHOYP_REPS1.2.2,,,,,,,REPS1_MOUSE,Mus musculus (Mouse), comp139086_c0_seq4,2562,43.2475,0.58616361,7,9,,5.00E-12,Q9Z0R6,Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B),Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B),GO:0005089; GO:0005509; GO:0005737; GO:0006897; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; calcium ion binding; cytoplasm; endocytosis; phospholipid binding; regulation of Rho protein signal transduction,PF00168;PF12763;PF16652;PF00621;PF00018;PF07653;PF14604;,,,,,,,,,ITSN2_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; positive regulation of dendrite extension [GO:1903861]; regulation of Rho protein signal transduction [GO:0035023] comp139086_c0_seq8,1624,45.0739,0.58439245,0,0,,4.00E-31,O54916,RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1),RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1),GO:0005509; GO:0005905; GO:0006898,calcium ion binding; coated pit; receptor-mediated endocytosis,PF12763;,2.00E-46,CHOYP_REPS1.2.2,,,,,,,REPS1_MOUSE,Mus musculus (Mouse), comp139087_c2_seq1,1543,31.7563,1.00422806,51,9,,3.00E-13,Q9IR51,Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3),Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3),GO:0005524; GO:0006200; GO:0042624; GO:0003677; GO:0006260; GO:0003723; GO:0003724; GO:0016888; GO:0042025; GO:0046872; GO:0090305; GO:0016779; GO:0018142,"ATP binding; ATP catabolic process; ATPase activity, uncoupled; DNA binding; DNA replication; RNA binding; RNA helicase activity; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotidyltransferase activity; protein-DNA covalent cross-linking",PF00910;PF02407;,,,,,,,,,MREP_MDV1,Milk vetch dwarf virus (isolate N) (MDV),DNA replication [GO:0006260]; protein-DNA covalent cross-linking [GO:0018142] comp139087_c2_seq3,1471,33.0387,1.28607464,2,2,,6.00E-09,P0CK60,Para-Rep C9 (Rep9) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3) (ATP-dependent helicase C9) (Replication-associated protein of non-essential DNA C9),Para-Rep C9 (Rep9) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3) (ATP-dependent helicase C9) (Replication-associated protein of non-essential DNA C9),GO:0005524; GO:0006200; GO:0042624; GO:0003677; GO:0006260; GO:0003723; GO:0003724; GO:0016888; GO:0042025; GO:0046872; GO:0090305; GO:0016779; GO:0018142,"ATP binding; ATP catabolic process; ATPase activity, uncoupled; DNA binding; DNA replication; RNA binding; RNA helicase activity; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotidyltransferase activity; protein-DNA covalent cross-linking",PF00910;PF02407;,,,,,,,,,REP9_FBNY1,Faba bean necrotic yellows virus (isolate Egyptian EV1-93) (FBNYV),DNA replication [GO:0006260]; protein-DNA covalent cross-linking [GO:0018142] comp139087_c2_seq4,1431,33.1936,1.23395149,0,0,,2.00E-13,Q9IR51,Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3),Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3),GO:0005524; GO:0006200; GO:0042624; GO:0003677; GO:0006260; GO:0003723; GO:0003724; GO:0016888; GO:0042025; GO:0046872; GO:0090305; GO:0016779; GO:0018142,"ATP binding; ATP catabolic process; ATPase activity, uncoupled; DNA binding; DNA replication; RNA binding; RNA helicase activity; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotidyltransferase activity; protein-DNA covalent cross-linking",PF00910;PF02407;,,,,,,,,,MREP_MDV1,Milk vetch dwarf virus (isolate N) (MDV),DNA replication [GO:0006260]; protein-DNA covalent cross-linking [GO:0018142] comp139088_c1_seq1,407,42.0147,0.58252779,28,768,,1.00E-23,Q3T0E8,Calmodulin-like protein 4,Calmodulin-like protein 4,GO:0005509,calcium ion binding,PF13499;PF13833;,,,,,,,,,CALL4_BOVIN,Bos taurus (Bovine), comp139089_c0_seq1,1577,37.5396,0.43802932,637,2609,,2.00E-73,Q0VCR1,Protein RTF2 homolog (Replication termination factor 2 domain-containing protein 1),Protein RTF2 homolog (Replication termination factor 2 domain-containing protein 1),,,PF04641;,8.00E-71,CHOYP_PHUM_PHUM177390.1.1,2.00E-69,ruditapes_c17516,,,,,CT043_BOVIN,Bos taurus (Bovine),mitotic DNA replication termination [GO:1902979] comp139091_c0_seq1,2339,35.186,0.36435508,168,572,,6.00E-128,A0AUR5,Protein FAM188A (Protein CARP),Protein FAM188A (Protein CARP),GO:0006915; GO:0005509; GO:0005634,apoptotic process; calcium ion binding; nucleus,PF13898;,,,,,,,,,F188A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915] comp139092_c0_seq1,2458,40.3987,0.91722906,11,40,,3.00E-25,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139092_c1_seq1,447,39.821,1.20000601,14,32,,5.00E-09,A5D7F8,E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (SH3 domain-containing RING finger protein 1),E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (SH3 domain-containing RING finger protein 1),GO:0005794; GO:0005829; GO:0030027; GO:0016874; GO:0043066; GO:0043154; GO:2001237; GO:0048471; GO:0016567; GO:0008270,Golgi apparatus; cytosol; lamellipodium; ligase activity; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; perinuclear region of cytoplasm; protein ubiquitination; zinc ion binding,PF07653;PF14604;PF00097;,,,,,,,,,SH3R1_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of JNK cascade [GO:0046328] comp139093_c0_seq1,2551,41.8267,1.10204157,49,787,,4.00E-33,P37801,Calponin homolog OV9M,Calponin homolog OV9M,,,PF00402;,2.00E-36,CHOYP_PHUM_PHUM289860.1.1,3.00E-95,ruditapes2_c1062,,,,,CLPH_ONCVO,Onchocerca volvulus, comp139093_c0_seq2,1673,38.1949,1.14981859,0,7,,7.00E-12,Q08093,"Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)","Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)",GO:0031032; GO:0071260; GO:0030097; GO:0030336; GO:0050765; GO:0010628; GO:0032970; GO:0042127; GO:0001725; GO:0042060,actomyosin structure organization; cellular response to mechanical stimulus; hemopoiesis; negative regulation of cell migration; negative regulation of phagocytosis; positive regulation of gene expression; regulation of actin filament-based process; regulation of cell proliferation; stress fiber; wound healing,PF00402;PF00307;,,,3.00E-35,ruditapes_c29611,,,,,CNN2_MOUSE,Mus musculus (Mouse),actomyosin structure organization [GO:0031032]; cellular response to mechanical stimulus [GO:0071260]; hemopoiesis [GO:0030097]; negative regulation of cell migration [GO:0030336]; negative regulation of phagocytosis [GO:0050765]; positive regulation of gene expression [GO:0010628]; regulation of actin filament-based process [GO:0032970]; regulation of cell proliferation [GO:0042127]; wound healing [GO:0042060] comp139095_c0_seq1,2528,41.4953,0.52629944,85,11,,2.00E-88,Q9NPB8,Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5),Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5),GO:0005829; GO:0006071; GO:0047389; GO:0008889; GO:0046474; GO:0044281; GO:2001070,cytosol; glycerol metabolic process; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; glycerophospholipid biosynthetic process; small molecule metabolic process; starch binding,PF00686;PF03009;,4.00E-32,CHOYP_GPC1A.1.1,,,,,,,GPCP1_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]; skeletal muscle tissue development [GO:0007519] comp139095_c0_seq2,1025,40.4878,0.36481332,0,0,,8.00E-26,Q02979,Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46),Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46),GO:0005737; GO:0006071; GO:0047389; GO:0008889; GO:0046475,cytoplasm; glycerol metabolic process; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; glycerophospholipid catabolic process,PF12796;PF03009;PF03105;,,,,,,,,,GDE1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475] comp139096_c6_seq1,779,40.3081,0.58209051,30,47,,3.00E-99,Q86TW2,Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-),GO:0005524; GO:0005576; GO:0005739; GO:0004674,ATP binding; extracellular region; mitochondrion; protein serine/threonine kinase activity,PF03109;,7.00E-55,CHOYP_LOC100369003.2.2,,,,,,,ADCK1_HUMAN,Homo sapiens (Human), comp139097_c0_seq1,2451,40.1469,1.10852227,2128,6,male>female,6.00E-10,Q8NA69,Uncharacterized protein C19orf45,Uncharacterized protein C19orf45,,,PF15373;,1.00E-13,CHOYP_BRAFLDRAFT_125998.1.1,,,,,,,CS045_HUMAN,Homo sapiens (Human), comp139098_c0_seq1,1731,41.2478,1.00224364,111,3442,,5.00E-51,P24329,Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),GO:0008097; GO:0016226; GO:0005743; GO:0005759; GO:0005886; GO:0035928; GO:0004792,5S rRNA binding; iron-sulfur cluster assembly; mitochondrial inner membrane; mitochondrial matrix; plasma membrane; rRNA import into mitochondrion; thiosulfate sulfurtransferase activity,PF00581;,2.00E-14,CHOYP_THTR.1.1,,,,,,,THTR_RAT,Rattus norvegicus (Rat),"epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" comp139100_c0_seq1,1967,43.3147,0.52367424,285,99,,0,P97363,Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2),Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2),GO:0046513; GO:0016021; GO:0005739; GO:0030170; GO:0004758; GO:0017059; GO:0046511; GO:0006686; GO:0046512,ceramide biosynthetic process; integral to membrane; mitochondrion; pyridoxal phosphate binding; serine C-palmitoyltransferase activity; serine C-palmitoyltransferase complex; sphinganine biosynthetic process; sphingomyelin biosynthetic process; sphingosine biosynthetic process,PF00155;,3.00E-121,CHOYP_SPTC2.4.4,2.00E-33,ruditapes_c22017,,,,,SPTC2_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] comp139102_c0_seq1,1350,43.5556,0.90680634,0,5472,,3.00E-111,Q6DG22,Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase),Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase),GO:0006154; GO:0004000; GO:0030054; GO:0060205; GO:0046103; GO:0009117; GO:0005886; GO:0009168; GO:0008270,adenosine catabolic process; adenosine deaminase activity; cell junction; cytoplasmic membrane-bounded vesicle lumen; inosine biosynthetic process; nucleotide metabolic process; plasma membrane; purine ribonucleoside monophosphate biosynthetic process; zinc ion binding,PF00962;,,,,,,,,,ADA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),adenosine catabolic process [GO:0006154]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110] comp139106_c5_seq1,1736,43.4908,0.50038661,94,658,,3.00E-132,Q10341,Probable serine-O-acetyltransferase cys2 (EC 2.3.1.-),Probable serine-O-acetyltransferase (EC 2.3.1.30),GO:0019344; GO:0004414; GO:0009086; GO:0005739,cysteine biosynthetic process; homoserine O-acetyltransferase activity; methionine biosynthetic process; mitochondrion,PF00561;,3.00E-171,CHOYP_LOC100374280.1.1,,,,,,,CYS2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cysteine biosynthetic process [GO:0019344]; methionine biosynthetic process [GO:0009086] comp139107_c2_seq2,962,34.5114,0.59412149,397,830,,,,,,,,,,,4.00E-13,ruditapes_c8275,,,,,,, comp139107_c2_seq4,460,30,0.77609794,1,103,,,,,,,,,,,9.00E-11,ruditapes_c21597,,,,,,, comp139109_c1_seq1,1804,42.3503,0.61918993,22,193,,3.00E-124,O15995,G1/S-specific cyclin-E,G1/S-specific cyclin-E,GO:0007049; GO:0051301; GO:0005634; GO:0000079,cell cycle; cell division; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,2.00E-52,CHOYP_LOC100371723.1.1,,,,,,,CCNE_HEMPU,Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus),cell cycle [GO:0007049]; cell division [GO:0051301] comp139109_c1_seq2,1364,42.2287,0.64462454,4,45,,4.00E-43,Q8MUK3,G1/S-specific cyclin-E,G1/S-specific cyclin-E,GO:0000082; GO:0051301; GO:0016538; GO:0005634; GO:0000079; GO:0007088,G1/S transition of mitotic cell cycle; cell division; cyclin-dependent protein serine/threonine kinase regulator activity; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of mitosis,PF00134;,,,,,,,,,CCNE_CAEBR,Caenorhabditis briggsae,cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; regulation of mitotic nuclear division [GO:0007088] comp139111_c0_seq1,951,42.3764,0.40276785,278,1010,,5.00E-31,Q9UTA8,Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-),Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-),GO:0044262; GO:0005829; GO:0005634; GO:0046547,cellular carbohydrate metabolic process; cytosol; nucleus; trans-aconitate 3-methyltransferase activity,PF08241;,7.00E-12,CHOYP_YL8A.1.1,2.00E-11,ruditapes_c26581,,,,,YL8A_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular carbohydrate metabolic process [GO:0044262]; methylation [GO:0032259] comp139113_c0_seq4,728,28.2967,0.89338404,9,21,,,,,,,,,3.00E-14,CHOYP_LOC100562878.1.2,,,,,,,,, comp139114_c0_seq2,1521,41.2886,0.55012829,5,33,,3.00E-33,P09543,"2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)","2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)",GO:0004113; GO:0003723; GO:0008344; GO:0007568; GO:0007409; GO:0030551; GO:0009214; GO:0005737; GO:0005615; GO:0030900; GO:0042470; GO:0005874; GO:0000226; GO:0005902; GO:0005743; GO:0005741; GO:0035748; GO:0035749; GO:0048471; GO:0005886; GO:0031143; GO:0046902; GO:0032496; GO:0009636; GO:0007268,"2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; RNA binding; adult locomotory behavior; aging; axonogenesis; cyclic nucleotide binding; cyclic nucleotide catabolic process; cytoplasm; extracellular space; forebrain development; melanosome; microtubule; microtubule cytoskeleton organization; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath abaxonal region; myelin sheath adaxonal region; perinuclear region of cytoplasm; plasma membrane; pseudopodium; regulation of mitochondrial membrane permeability; response to lipopolysaccharide; response to toxic substance; synaptic transmission",PF05881;,,,,,,,,,CN37_HUMAN,Homo sapiens (Human),adult locomotory behavior [GO:0008344]; aging [GO:0007568]; axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268]; cyclic nucleotide catabolic process [GO:0009214]; forebrain development [GO:0030900]; microtubule cytoskeleton organization [GO:0000226]; oligodendrocyte differentiation [GO:0048709]; regulation of mitochondrial membrane permeability [GO:0046902]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; substantia nigra development [GO:0021762] comp139115_c0_seq1,1232,31.8182,0.3297499,349,709,,,,,,,,,9.00E-12,CHOYP_ND5.6.6,9.00E-35,ruditapes_c1316,,,,,,, comp139115_c0_seq3,1960,31.5816,0.23039054,721,639,,,,,,,,,1.00E-11,CHOYP_ND5.6.6,,,,,,,,, comp139118_c2_seq2,922,36.1171,0.31392222,29,66,,4.00E-57,Q13371,Phosducin-like protein (PHLP),Phosducin-like protein (PHLP),GO:0061084; GO:0006457; GO:0007165; GO:0007601,negative regulation of protein refolding; protein folding; signal transduction; visual perception,PF02114;,2.00E-36,CHOYP_PHLP.1.1,2.00E-55,ruditapes_c14404,,,,,PHLP_HUMAN,Homo sapiens (Human),heterotrimeric G-protein complex assembly [GO:1902605]; negative regulation of protein refolding [GO:0061084]; protein folding [GO:0006457]; queuosine biosynthetic process [GO:0008616]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; signal transduction [GO:0007165]; visual perception [GO:0007601] comp139119_c0_seq2,448,43.5268,0.33133203,19,110,,5.00E-09,B6HK90,Structure-specific endonuclease subunit slx1 (EC 3.6.1.-),Structure-specific endonuclease subunit slx1 (EC 3.1.-.-),GO:0017108; GO:0006310; GO:0006281; GO:0033557; GO:0046872,5'-flap endonuclease activity; DNA recombination; DNA repair; Slx1-Slx4 complex; metal ion binding,PF11793;PF01541;,,,,,,,,,SLX1_PENCW,Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum),"DNA catabolic process, endonucleolytic [GO:0000737]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]" comp139119_c0_seq6,393,44.2748,0.68770585,0,17,,3.00E-35,A7STV9,Structure-specific endonuclease subunit SLX1 homolog (EC 3.6.1.-),Structure-specific endonuclease subunit SLX1 homolog (EC 3.1.-.-),GO:0017108; GO:0006310; GO:0006281; GO:0033557; GO:0046872,5'-flap endonuclease activity; DNA recombination; DNA repair; Slx1-Slx4 complex; metal ion binding,PF01541;,,,,,,,,,SLX1_NEMVE,Nematostella vectensis (Starlet sea anemone),DNA recombination [GO:0006310]; DNA repair [GO:0006281] comp139121_c0_seq1,1241,41.9823,0.82054107,205,1344,,9.00E-68,Q91X52,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0016324; GO:0005903; GO:0005881; GO:0006006; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; apical plasma membrane; brush border; cytoplasmic microtubule; glucose metabolic process; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,1.00E-39,ruditapes2_c2560,,,,,DCXR_MOUSE,Mus musculus (Mouse),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp139123_c0_seq1,2587,39.9304,0.49713406,24,27,,,,,,,,,5.00E-12,CHOYP_LOC100493440.1.2,,,,,,,,, comp139123_c0_seq2,3886,39.1148,0.54522908,168,378,,,,,,,,,6.00E-20,CHOYP_LOC100492160.3.3,,,,,,,,, comp139131_c0_seq1,544,44.8529,0.73728604,23,34,,1.00E-50,Q6GPD0,Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS),Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS),GO:0005096; GO:0005737; GO:0035091; GO:0005886; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; phosphatidylinositol binding; plasma membrane; positive regulation of GTPase activity; signal transduction,PF00620;PF07653;,3.00E-38,CHOYP_LOC100889543.1.1,,,,,,,RHG32_XENLA,Xenopus laevis (African clawed frog),signal transduction [GO:0007165] comp139131_c3_seq2,2254,45.9184,0.64279726,82,71,,2.00E-133,Q6GPD0,Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS),Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS),GO:0005096; GO:0005737; GO:0035091; GO:0005886; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; phosphatidylinositol binding; plasma membrane; positive regulation of GTPase activity; signal transduction,PF00620;PF07653;,5.00E-138,CHOYP_LOC656615.1.1,,,,,,,RHG32_XENLA,Xenopus laevis (African clawed frog),signal transduction [GO:0007165] comp139135_c0_seq1,1577,40.5834,0.4514088,2501,493,,4.00E-127,Q86XH1,IQ and AAA domain-containing protein 1,IQ and AAA domain-containing protein 1,GO:0005524,ATP binding,PF00004;,0,CHOYP_IQCA1.3.3,1.00E-122,ruditapes_c11017,,,,,IQCA1_HUMAN,Homo sapiens (Human), comp139141_c1_seq1,3684,40.3094,0.72510828,496,171,,3.00E-06,B4JTF5,Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product],Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product],GO:0009653; GO:0045168; GO:0005737; GO:0005615; GO:0016539; GO:0016015; GO:0005634; GO:0008233; GO:0005886; GO:0006508; GO:0007367,anatomical structure morphogenesis; cell-cell signaling involved in cell fate commitment; cytoplasm; extracellular space; intein-mediated protein splicing; morphogen activity; nucleus; peptidase activity; plasma membrane; proteolysis; segment polarity determination,PF01085;PF01079;,,,3.00E-71,ruditapes_c2009,,,,,HH_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi),anatomical structure morphogenesis [GO:0009653]; cell-cell signaling involved in cell fate commitment [GO:0045168]; intein-mediated protein splicing [GO:0016539]; segment polarity determination [GO:0007367] comp139142_c1_seq1,3531,41.6879,0.98415112,1430,19389,,7.00E-104,Q5RB37,Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,4.00E-15,CHOYP_ITIH3.3.3,,,,,,,ITIH3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),hyaluronan metabolic process [GO:0030212] comp139145_c0_seq2,1778,33.1271,0.62000484,34,251,,8.00E-95,O60573,Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (mRNA cap-binding protein type 3),Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (mRNA cap-binding protein type 3),GO:0000339; GO:0019221; GO:0005829; GO:0001701; GO:0005845; GO:0017148; GO:0008135; GO:0003743,"RNA cap binding; cytokine-mediated signaling pathway; cytosol; in utero embryonic development; mRNA cap binding complex; negative regulation of translation; translation factor activity, nucleic acid binding; translation initiation factor activity",PF01652;,3.00E-89,CHOYP_BRAFLDRAFT_265613.2.2,,,2.00E-90,AM866997.p.cg.6,9,,IF4E2_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701]; negative regulation of translation [GO:0017148] comp139148_c0_seq11,1506,35.7902,0.58435146,0,1,,3.00E-54,P97576,"GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)","GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)",GO:0000774; GO:0005759; GO:0006457,adenyl-nucleotide exchange factor activity; mitochondrial matrix; protein folding,PF01025;,8.00E-20,CHOYP_LOC100619435.1.2,,,,,,,GRPE1_RAT,Rattus norvegicus (Rat),protein folding [GO:0006457] comp139148_c0_seq4,1573,35.6008,0.60675395,53,241,,4.00E-54,P97576,"GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)","GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)",GO:0000774; GO:0005759; GO:0006457,adenyl-nucleotide exchange factor activity; mitochondrial matrix; protein folding,PF01025;,,,,,,,,,GRPE1_RAT,Rattus norvegicus (Rat),protein folding [GO:0006457] comp139148_c0_seq8,1517,35.6625,0.58458517,0,4,,4.00E-19,A7ZEB6,Protein GrpE (HSP-70 cofactor),Protein GrpE (HSP-70 cofactor),GO:0000774; GO:0005737; GO:0006457; GO:0006950,adenyl-nucleotide exchange factor activity; cytoplasm; protein folding; response to stress,PF01025;,,,,,,,,,GRPE_CAMC1,Campylobacter concisus (strain 13826),protein folding [GO:0006457] comp139149_c0_seq1,1327,37.3775,0.79954484,529,1491,,9.00E-54,Q9BR09,Neuralized-like protein 2,Neuralized-like protein 2,GO:0030891; GO:0035556; GO:0005927; GO:0016567; GO:0045214,VCB complex; intracellular signal transduction; muscle tendon junction; protein ubiquitination; sarcomere organization,PF07177;PF07525;,2.00E-39,CHOYP_CLPB.3.3,,,,,,,NEUL2_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp139150_c0_seq1,6635,41.4017,0.74585331,0,293,female,5.00E-94,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,2.00E-84,CHOYP_LOC100372741.2.3,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp139150_c0_seq2,7235,40.5943,0.78585442,5,299,,1.00E-76,Q8I7P9,Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305; GO:0005634; GO:0008233; GO:0006508; GO:0006313,"DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; peptidase activity; proteolysis; transposition, DNA-mediated",PF00665;PF00078;,2.00E-68,CHOYP_LOC578054.2.7,,,,,,,POL5_DROME,Drosophila melanogaster (Fruit fly),"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp139150_c0_seq3,6619,41.3809,0.74883958,1,424,female>male,5.00E-94,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,2.00E-84,CHOYP_LOC100372741.2.3,1.00E-79,ruditapes_c31830,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp139150_c0_seq4,7219,40.5735,0.78883859,3,400,,6.00E-94,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,1.00E-68,CHOYP_LOC578054.2.7,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp139151_c0_seq1,1260,35.7143,0.47566986,0,13,,,,,,,,,,,5.00E-82,ruditapes_c9557,,,,,,, comp139151_c0_seq2,1349,47.3684,0.3194323,14,0,,1.00E-79,Q95LN2,Tetratricopeptide repeat protein 18 (TPR repeat protein 18),Cilia- and flagella-associated protein 70,,,PF13181;,,,,,,,,,TTC18_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp139151_c0_seq3,2279,40.5002,0.46090931,1132,176,,,,,,,,,0,CHOYP_LOC100368394.1.2,,,,,,,,, comp139151_c0_seq4,1359,47.2406,0.29228756,0,1,,1.00E-79,Q95LN2,Tetratricopeptide repeat protein 18 (TPR repeat protein 18),Cilia- and flagella-associated protein 70,,,PF13181;,,,,,,,,,TTC18_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp139153_c0_seq1,1014,37.6726,0.62758275,21,269,,5.00E-58,Q24799,Myophilin,Myophilin,,,PF00402;PF00307;,2.00E-45,CHOYP_MYPH.1.2,,,,,,,MYPH_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp139153_c0_seq2,554,44.9458,0.62566517,4,12,,2.00E-14,Q55E26,Rac guanine nucleotide exchange factor B,Rac guanine nucleotide exchange factor B,GO:0005089; GO:0051764; GO:0051015; GO:0005938; GO:0006897; GO:0006887; GO:0035556; GO:0005770; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; actin crosslink formation; actin filament binding; cell cortex; endocytosis; exocytosis; intracellular signal transduction; late endosome; phospholipid binding; regulation of Rho protein signal transduction,PF00307;PF00621;,,,,,,,,,GXCB_DICDI,Dictyostelium discoideum (Slime mold),actin crosslink formation [GO:0051764]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023] comp139155_c0_seq1,2181,38.1018,0.4585426,92,111,,7.00E-78,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,2.00E-36,CHOYP_BRAFLDRAFT_118535.8.8,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp139158_c0_seq1,1987,35.531,0.93118538,5811,60556,,1.00E-22,Q9Y4K0,Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14),Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14),GO:0007568; GO:0005604; GO:0007155; GO:0003682; GO:0005694; GO:0030199; GO:0005507; GO:0009055; GO:0043542; GO:0001935; GO:0001837; GO:0005615; GO:0016570; GO:0016020; GO:0035064; GO:0045892; GO:0005634; GO:0070492; GO:0032332; GO:0018277; GO:0004720; GO:0046688; GO:0001666; GO:0005044; GO:0002040; GO:0003714; GO:0006351,"aging; basement membrane; cell adhesion; chromatin binding; chromosome; collagen fibril organization; copper ion binding; electron carrier activity; endothelial cell migration; endothelial cell proliferation; epithelial to mesenchymal transition; extracellular space; histone modification; membrane; methylated histone residue binding; negative regulation of transcription, DNA-dependent; nucleus; oligosaccharide binding; positive regulation of chondrocyte differentiation; protein deamination; protein-lysine 6-oxidase activity; response to copper ion; response to hypoxia; scavenger receptor activity; sprouting angiogenesis; transcription corepressor activity; transcription, DNA-dependent",PF01186;PF00530;,,,,,,,,,LOXL2_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; histone modification [GO:0016570]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidation-reduction process [GO:0055114]; positive regulation of chondrocyte differentiation [GO:0032332]; protein deamination [GO:0018277]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp139162_c0_seq9,413,25.1816,0.92000539,0,0,,,,,,,,,,,1.00E-13,ruditapes_c20166,,,,,,, comp139163_c0_seq1,1966,38.1485,0.56310625,2,0,,6.00E-06,Q5ZHN5,THAP domain-containing protein 5,THAP domain-containing protein 5,GO:0003677; GO:0046872; GO:0005634,DNA binding; metal ion binding; nucleus,PF05485;,,,,,,,,,THAP5_CHICK,Gallus gallus (Chicken), comp139163_c0_seq2,1984,38.1552,0.57204625,11,38,,6.00E-07,B5XCB8,THAP domain-containing protein 1,THAP domain-containing protein 1,GO:0007049; GO:0046872; GO:0005654; GO:0006355; GO:0043565; GO:0006351,"cell cycle; metal ion binding; nucleoplasm; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF05485;,,,,,,,,,THAP1_SALSA,Salmo salar (Atlantic salmon),"cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139165_c0_seq1,1808,37.7212,0.52332753,15,754,,0,P79733,Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase protein R2 class I) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit),Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase protein R2 class I) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit),GO:0006260; GO:0005737; GO:0009186; GO:0046872; GO:0004748,"DNA replication; cytoplasm; deoxyribonucleoside diphosphate metabolic process; metal ion binding; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",PF00268;,,,,,,,,,RIR2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),deoxyribonucleoside diphosphate metabolic process [GO:0009186]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260] comp139165_c0_seq2,1800,37.5,0.4988208,536,1853,,0,P07201,Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (p41),Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (p41),GO:0006260; GO:0009186; GO:0046872; GO:0004748,"DNA replication; deoxyribonucleoside diphosphate metabolic process; metal ion binding; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",PF00268;,0,CHOYP_RIR2.1.1,4.00E-86,ruditapes_c11036,5.00E-83,AM237649.p.cg.6,9,,RIR2_SPISO,Spisula solidissima (Atlantic surf-clam),deoxyribonucleoside diphosphate metabolic process [GO:0009186]; DNA replication [GO:0006260] comp139166_c0_seq1,1233,40.3082,0.48256566,28,72,,,,,,,,,7.00E-121,CHOYP_DHSB.1.1,,,,,,,,, comp139166_c0_seq2,1245,40.241,0.49913505,84,416,,1.00E-141,Q9YHT2,"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip)","Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip)",GO:0051537; GO:0051538; GO:0051539; GO:0009055; GO:0046872; GO:0005749; GO:0044281; GO:0008177; GO:0006099; GO:0048039,"2 iron, 2 sulfur cluster binding; 3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; electron carrier activity; metal ion binding; mitochondrial respiratory chain complex II; small molecule metabolic process; succinate dehydrogenase (ubiquinone) activity; tricarboxylic acid cycle; ubiquinone binding",PF13085;,7.00E-121,CHOYP_DHSB.1.1,,,,,,,DHSB_CHICK,Gallus gallus (Chicken),tricarboxylic acid cycle [GO:0006099] comp139167_c0_seq1,1367,40.0146,0.47873397,0,0,,3.00E-129,C5XKZ1,"Lipoyl synthase, chloroplastic (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoate synthase, plastidial) (LIP1p) (Lipoic acid synthase)","Lipoyl synthase, chloroplastic (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoate synthase, plastidial) (LIP1p) (Lipoic acid synthase)",GO:0051539; GO:0009507; GO:0016992; GO:0046872; GO:0009249,"4 iron, 4 sulfur cluster binding; chloroplast; lipoate synthase activity; metal ion binding; protein lipoylation",PF04055;,4.00E-130,CHOYP_LIAS.1.1,,,,,,,LISC_SORBI,Sorghum bicolor (Sorghum) (Sorghum vulgare),lipoate biosynthetic process [GO:0009107]; protein lipoylation [GO:0009249] comp139167_c0_seq7,954,43.3962,0.40575992,0,0,,,,,,,,,,,2.00E-28,ruditapes_c11466,,,,,,, comp139167_c0_seq9,1368,40.4971,0.47016735,0,0,,3.00E-168,Q5BIP7,"Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase)","Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase)",GO:0051539; GO:0016992; GO:0046872; GO:0005739,"4 iron, 4 sulfur cluster binding; lipoate synthase activity; metal ion binding; mitochondrion",PF16881;PF04055;,2.00E-134,CHOYP_LIAS.1.1,,,,,,,LIAS_BOVIN,Bos taurus (Bovine),inflammatory response [GO:0006954]; lipoate biosynthetic process [GO:0009107]; neural tube closure [GO:0001843]; protein lipoylation [GO:0009249]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979] comp139168_c0_seq1,2620,40.4198,0.4538889,80,417,,0,O62703,Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (p14),Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (p14),GO:0000974; GO:0008380; GO:0006915; GO:0006397; GO:0005681,Prp19 complex; RNA splicing; apoptotic process; mRNA processing; spliceosomal complex,PF08216;,0,CHOYP_CTBL1.1.1,,,,,,,CTBL1_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp139168_c0_seq3,1498,38.7183,0.33914446,0,7,,2.00E-54,O62703,Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (p14),Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (p14),GO:0000974; GO:0008380; GO:0006915; GO:0006397; GO:0005681,Prp19 complex; RNA splicing; apoptotic process; mRNA processing; spliceosomal complex,PF08216;,,,,,,,,,CTBL1_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp139170_c0_seq1,1032,47.5775,0.36900422,106,29,,7.00E-57,P54729,NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Protein BS4),NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Protein BS4),GO:0005634; GO:0032436; GO:0016567; GO:0034341; GO:0034612; GO:0006511,nucleus; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; response to interferon-gamma; response to tumor necrosis factor; ubiquitin-dependent protein catabolic process,PF00627;,1.00E-33,CHOYP_LOC583762.1.1,,,,,,,NUB1_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] comp139175_c0_seq1,1479,45.0304,0.32106167,2,5,,3.00E-41,Q8IY37,Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37),Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX37_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396]; rRNA processing [GO:0006364] comp139175_c0_seq2,2214,44.7606,0.39936411,24,41,,0,Q9H5Z1,Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35),Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35),GO:0005524; GO:0008026; GO:0071013; GO:0000398; GO:0003676,"ATP binding; ATP-dependent helicase activity; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleic acid binding",PF04408;PF00271;PF07717;,0,CHOYP_DHX35.1.1,,,,,,,DHX35_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]" comp139175_c0_seq3,1563,45.0416,0.32878675,0,0,,2.00E-39,Q8VHK9,Probable ATP-dependent RNA helicase DHX36 (EC 3.6.4.13) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE),ATP-dependent RNA helicase DHX36 (EC 3.6.4.13) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE),GO:0005524; GO:0008026; GO:0003725; GO:0005634; GO:0043330; GO:0009615,ATP binding; ATP-dependent helicase activity; double-stranded RNA binding; nucleus; response to exogenous dsRNA; response to virus,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX36_MOUSE,Mus musculus (Mouse),"ossification [GO:0001503]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]" comp139175_c0_seq4,1758,44.653,0.36627722,5,4,,4.00E-39,Q6PGC1,ATP-dependent RNA helicase Dhx29 (EC 3.6.4.13) (DEAH box protein 29),ATP-dependent RNA helicase Dhx29 (EC 3.6.4.13) (DEAH box protein 29),GO:0005524; GO:0008026; GO:0016282; GO:0005739; GO:0043024; GO:0003743,ATP binding; ATP-dependent helicase activity; eukaryotic 43S preinitiation complex; mitochondrion; ribosomal small subunit binding; translation initiation factor activity,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_DHX35.1.1,,,,,,,DHX29_MOUSE,Mus musculus (Mouse),RNA processing [GO:0006396] comp139176_c1_seq1,1624,38.2389,0.98036194,0,429,,7.00E-49,Q7LFX5,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0030206; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; chondroitin sulfate biosynthetic process; hexose biosynthetic process; integral to membrane,,,,,,,,,,CHSTF_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319] comp139176_c1_seq2,1645,37.9331,0.98331447,11,544,female>male,8.00E-49,Q7LFX5,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0030206; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; chondroitin sulfate biosynthetic process; hexose biosynthetic process; integral to membrane,,,,,,,,,,CHSTF_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319] comp139178_c2_seq1,1578,43.7896,0.4093857,8,3,,7.00E-14,Q54KD0,TPR repeat-containing protein DDB_G0287407,TPR repeat-containing protein DDB_G0287407,GO:0017111; GO:0000166,nucleoside-triphosphatase activity; nucleotide binding,PF13271;,,,,,,,,,Y7407_DICDI,Dictyostelium discoideum (Slime mold), comp139178_c2_seq2,2421,42.7922,0.43095593,0,0,,1.00E-08,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp139178_c2_seq3,2304,42.9688,0.43152864,2,0,,3.00E-07,Q7Z494,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0003283; GO:0060271; GO:0060027; GO:0071908; GO:0071910; GO:0035469; GO:0071909; GO:0060287; GO:0007163; GO:0030198; GO:0001947; GO:0060993; GO:0006629; GO:0030324; GO:0048496; GO:0090090; GO:0045494; GO:0072372; GO:0030814; GO:2000167; GO:0072189,Wnt receptor signaling pathway; atrial septum development; cilium morphogenesis; convergent extension involved in gastrulation; determination of intestine left/right asymmetry; determination of liver left/right asymmetry; determination of pancreatic left/right asymmetry; determination of stomach left/right asymmetry; epithelial cilium movement involved in determination of left/right asymmetry; establishment or maintenance of cell polarity; extracellular matrix organization; heart looping; kidney morphogenesis; lipid metabolic process; lung development; maintenance of organ identity; negative regulation of canonical Wnt receptor signaling pathway; photoreceptor cell maintenance; primary cilium; regulation of cAMP metabolic process; regulation of planar cell polarity pathway involved in neural tube closure; ureter development,PF13176;,,,,,,,,,NPHP3_HUMAN,Homo sapiens (Human),"atrial septum development [GO:0003283]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lung development [GO:0030324]; maintenance of organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055]" comp139178_c2_seq4,2420,42.7273,0.43318249,0,0,,,,,,,,,0,CHOYP_BRAFLDRAFT_121887.1.1,,,,,,,,, comp139178_c2_seq7,1580,43.8608,0.40663597,0,0,,6.00E-09,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp139178_c2_seq8,2303,42.9006,0.43429432,0,0,,2.00E-09,Q54KD0,TPR repeat-containing protein DDB_G0287407,TPR repeat-containing protein DDB_G0287407,GO:0017111; GO:0000166,nucleoside-triphosphatase activity; nucleotide binding,PF13271;,,,,,,,,,Y7407_DICDI,Dictyostelium discoideum (Slime mold), comp139178_c2_seq9,1696,43.4552,0.41024416,0,0,,1.00E-09,Q54KD0,TPR repeat-containing protein DDB_G0287407,TPR repeat-containing protein DDB_G0287407,GO:0017111; GO:0000166,nucleoside-triphosphatase activity; nucleotide binding,PF13271;,1.00E-119,CHOYP_BRAFLDRAFT_121887.1.1,,,,,,,Y7407_DICDI,Dictyostelium discoideum (Slime mold), comp139179_c0_seq1,1165,40.2575,0.4582822,70,200,,2.00E-58,Q9NP81,"Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)","Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)",GO:0005524; GO:0005759; GO:0097056; GO:0004828; GO:0006434,ATP binding; mitochondrial matrix; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF00587;,,,,,,,,,SYSM_HUMAN,Homo sapiens (Human),selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]; tRNA aminoacylation for protein translation [GO:0006418] comp139181_c0_seq1,1090,38.6239,0.59414618,101,395,,8.00E-65,Q0V9K2,Alpha/beta hydrolase domain-containing protein 11 (Abhydrolase domain-containing protein 11) (EC 3.-.-.-),Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11),GO:0016787,hydrolase activity,PF00561;,,,,,,,,,ABHDB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp139183_c0_seq2,1086,35.5433,0.37940695,77,424,,2.00E-40,Q8TC21,Zinc finger protein 596,Zinc finger protein 596,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN596_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139183_c0_seq4,1019,35.1325,0.44569331,43,69,,7.00E-10,P18712,Gastrula zinc finger protein XlCGF16.1 (Fragment),Gastrula zinc finger protein XlCGF16.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG16_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139187_c0_seq2,1145,39.3886,0.23045384,3,43,,6.00E-55,Q5M8L0,OTU domain-containing protein 6B (EC 3.4.19.12),OTU domain-containing protein 6B (EC 3.4.19.12),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF02338;,,,,,,,,,OTU6B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp139194_c0_seq1,1394,47.2023,0.57741763,0,0,,1.00E-69,P58270,Zinc finger protein DPF3 (Zinc finger protein cer-d4),Zinc finger protein DPF3 (Zinc finger protein cer-d4),GO:0016568; GO:0007399; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"chromatin modification; nervous system development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,8.00E-64,CHOYP_ISCW_ISCW007807.1.1,,,,,,,DPF3_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139194_c0_seq2,1379,47.0631,0.57455571,0,16,,9.00E-68,Q9W638,Zinc finger protein ubi-d4 A (Apoptosis response zinc finger protein A) (Protein requiem A) (xReq A),Zinc finger protein ubi-d4 A (Apoptosis response zinc finger protein A) (Protein requiem A) (xReq A),GO:0006915; GO:0005737; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"apoptotic process; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,,,,,,,,,REQUA_XENLA,Xenopus laevis (African clawed frog),"apoptotic process [GO:0006915]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139194_c0_seq3,1338,47.0105,0.59354123,0,0,,3.00E-91,Q92784,Zinc finger protein DPF3 (BRG1-associated factor 45C) (BAF45C) (Zinc finger protein cer-d4),Zinc finger protein DPF3 (BRG1-associated factor 45C) (BAF45C) (Zinc finger protein cer-d4),GO:0016568; GO:0071565; GO:0007399; GO:0006355; GO:0006351; GO:0008270,"chromatin modification; nBAF complex; nervous system development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,,,,,,,,,DPF3_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nervous system development [GO:0007399]; positive regulation of defense response to virus by host [GO:0002230]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; xenophagy [GO:0098792]" comp139194_c0_seq6,824,41.6262,0.50078628,3,2,,7.00E-46,P58267,"Zinc finger protein neuro-d4 (D4, zinc and double PHD fingers family 1)","Zinc finger protein neuro-d4 (D4, zinc and double PHD fingers family 1)",GO:0005737; GO:0007399; GO:0003676; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"cytoplasm; nervous system development; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,4.00E-64,CHOYP_ISCW_ISCW007807.1.1,1.00E-44,ruditapes_c8486,,,,,DPF1_CHICK,Gallus gallus (Chicken),"nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139195_c1_seq1,1493,40.9913,0.56060063,60,568,,6.00E-129,Q6PFP6,NADPH-dependent diflavin oxidoreductase 1 (EC 1.6.-.-) (NADPH-dependent FMN and FAD-containing oxidoreductase),NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase),GO:0010181; GO:0003958; GO:0008219; GO:0036245; GO:0005829; GO:0005506; GO:0016709; GO:0048471,"FMN binding; NADPH-hemoprotein reductase activity; cell death; cellular response to menadione; cytosol; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; perinuclear region of cytoplasm",PF00667;PF00258;PF00175;,1.00E-22,CHOYP_BRAFLDRAFT_122922.1.1,,,,,,,NDOR1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226] comp139196_c0_seq1,1809,41.2935,0.3682873,3346,11833,,0,Q9DE27,RuvB-like 2 (EC 3.6.4.12) (Reptin),RuvB-like 2 (EC 3.6.4.12) (Reptin),GO:0005524; GO:0043141; GO:0032508; GO:0006310; GO:0006281; GO:0071339; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 5'-3' DNA helicase activity; DNA duplex unwinding; DNA recombination; DNA repair; MLL1 complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF06068;,0,CHOYP_RUVB2.1.1,2.00E-76,ruditapes_c9886,,,,,RUVB2_XENLA,Xenopus laevis (African clawed frog),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139197_c1_seq2,1911,38.5139,0.53752382,585,1654,,7.00E-59,Q5XGG2,Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-),Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-),GO:0003723; GO:0009982; GO:0001522; GO:0008033,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; tRNA processing,PF01509;,,,,,,,,,TRUB2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033] comp139198_c0_seq1,1157,39.5851,0.84041316,54,216,,6.00E-34,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp139198_c0_seq2,816,41.6667,0.82008361,0,0,,2.00E-26,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp139200_c0_seq1,2070,40.9179,0.41953283,9,18,,,,,,,,,3.00E-58,CHOYP_MGC154513.1.1,,,,,,,,, comp139200_c0_seq4,1811,42.2419,0.43915423,0,0,,9.00E-98,Q2NL14,KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog),KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog),GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123,histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex,PF13891;,3.00E-58,CHOYP_MGC154513.1.1,,,,,,,KANL2_BOVIN,Bos taurus (Bovine),histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982] comp139203_c0_seq10,1977,43.1968,0.52348829,0,0,,8.00E-07,O23320,Calmodulin-like protein 8 (AtCaM-8),Calmodulin-like protein 8 (AtCaM-8),GO:0005509; GO:0019722; GO:0005513,calcium ion binding; calcium-mediated signaling; detection of calcium ion,PF13499;,,,,,,,,,CML8_ARATH,Arabidopsis thaliana (Mouse-ear cress),calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513] comp139203_c0_seq11,1964,42.7189,0.59417056,0,0,,0,Q9UJS0,Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13),Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13),GO:0006754; GO:0015183; GO:0005313; GO:0005509; GO:0006094; GO:0005887; GO:0043490; GO:0005743; GO:0051592,ATP biosynthetic process; L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; calcium ion binding; gluconeogenesis; integral to plasma membrane; malate-aspartate shuttle; mitochondrial inner membrane; response to calcium ion,PF00153;,0,CHOYP_LOC100901947.1.1,,,,,,,CMC2_HUMAN,Homo sapiens (Human),aspartate transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; response to calcium ion [GO:0051592]; translation [GO:0006412]; transport [GO:0006810] comp139203_c0_seq12,1047,40.0191,0.57511371,0,0,,3.00E-07,P02597,"Calmodulin, striated muscle","Calmodulin, striated muscle",GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALMS_CHICK,Gallus gallus (Chicken), comp139203_c0_seq4,2291,42.6888,0.52108245,0,0,,0,Q9UJS0,Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13),Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13),GO:0006754; GO:0015183; GO:0005313; GO:0005509; GO:0006094; GO:0005887; GO:0043490; GO:0005743; GO:0051592,ATP biosynthetic process; L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; calcium ion binding; gluconeogenesis; integral to plasma membrane; malate-aspartate shuttle; mitochondrial inner membrane; response to calcium ion,PF00153;,,,,,,,,,CMC2_HUMAN,Homo sapiens (Human),aspartate transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; response to calcium ion [GO:0051592]; translation [GO:0006412]; transport [GO:0006810] comp139203_c0_seq5,2806,40.9123,0.54227082,0,0,,0,Q9UJS0,Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13),Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13),GO:0006754; GO:0015183; GO:0005313; GO:0005509; GO:0006094; GO:0005887; GO:0043490; GO:0005743; GO:0051592,ATP biosynthetic process; L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; calcium ion binding; gluconeogenesis; integral to plasma membrane; malate-aspartate shuttle; mitochondrial inner membrane; response to calcium ion,PF00153;,,,,,,,,,CMC2_HUMAN,Homo sapiens (Human),aspartate transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; response to calcium ion [GO:0051592]; translation [GO:0006412]; transport [GO:0006810] comp139203_c0_seq6,1650,43.3333,0.60860415,0,0,,1.00E-77,Q12482,Mitochondrial aspartate-glutamate transporter AGC1 (Aspartate-glutamate carrier 1),Mitochondrial aspartate-glutamate transporter AGC1 (Aspartate-glutamate carrier 1),GO:0015183; GO:0005313; GO:0015297; GO:0044271; GO:0016021; GO:0005743; GO:0015292,L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; antiporter activity; cellular nitrogen compound biosynthetic process; integral to membrane; mitochondrial inner membrane; uniporter activity,PF00153;,,,,,,,,,AGC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),aspartate transport [GO:0015810]; cellular nitrogen compound biosynthetic process [GO:0044271]; L-glutamate transport [GO:0015813]; translation [GO:0006412] comp139203_c0_seq8,2479,40.7019,0.60885414,0,0,,3.00E-77,Q75AH6,Mitochondrial aspartate-glutamate transporter AGC1 (Aspartate-glutamate carrier 1),Mitochondrial aspartate-glutamate transporter AGC1 (Aspartate-glutamate carrier 1),GO:0006865; GO:0016021; GO:0005743; GO:0055085,amino acid transport; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,0,CHOYP_LOC100901947.1.1,,,,,,,AGC1_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),amino acid transport [GO:0006865]; translation [GO:0006412]; transmembrane transport [GO:0055085] comp139206_c0_seq1,1716,39.3939,0.61201778,2182,2360,,1.00E-102,Q8N806,Putative E3 ubiquitin-protein ligase UBR7 (EC 6.3.2.-) (N-recognin-7),Putative E3 ubiquitin-protein ligase UBR7 (EC 6.3.2.-) (N-recognin-7),GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,PF02207;,7.00E-59,CHOYP_UBR7.1.1,,,,,,,UBR7_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp139207_c0_seq1,1928,38.1743,0.45582644,909,3757,,4.00E-35,Q3ZAU7,Centromere protein L (CENP-L),Centromere protein L (CENP-L),GO:0000775; GO:0005634,"chromosome, centromeric region; nucleus",PF13092;,,,,,,,,,CENPL_RAT,Rattus norvegicus (Rat), comp139209_c0_seq1,2228,35.9964,0.92888883,0,0,,1.00E-37,A2T737,ETS homologous factor (ETS domain-containing transcription factor),ETS homologous factor (ETS domain-containing transcription factor),GO:0030855; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"epithelial cell differentiation; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,5.00E-37,CHOYP_PHUM_PHUM500930.1.1,,,,,,,EHF_PANTR,Pan troglodytes (Chimpanzee),cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp139209_c0_seq10,2160,35.7407,0.91383427,0,0,,7.00E-38,Q32LN0,ETS homologous factor (ETS domain-containing transcription factor),ETS homologous factor (ETS domain-containing transcription factor),GO:0030855; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"epithelial cell differentiation; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,,,3.00E-49,ruditapes2_c2760,,,,,EHF_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp139209_c0_seq3,2215,36.0722,0.90257431,0,0,,1.00E-37,A2T737,ETS homologous factor (ETS domain-containing transcription factor),ETS homologous factor (ETS domain-containing transcription factor),GO:0030855; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"epithelial cell differentiation; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,,,,,,,,,EHF_PANTR,Pan troglodytes (Chimpanzee),cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp139209_c0_seq4,2303,36.3005,0.93677863,0,0,,,,,,,,,,,1.00E-117,ruditapes_c11272,,,,,,, comp139209_c0_seq6,2358,36.5988,0.92533681,0,0,,,,,,,,,1.00E-76,CHOYP_PHUM_PHUM500930.1.1,,,,,,,,, comp139209_c0_seq7,2345,36.6738,0.90115578,0,0,,,,,,,,,1.00E-76,CHOYP_PHUM_PHUM500930.1.1,,,,,,,,, comp139209_c0_seq9,2173,35.665,0.94127619,0,0,,1.00E-32,Q8VDK3,ETS-related transcription factor Elf-5 (E74-like factor 5),ETS-related transcription factor Elf-5 (E74-like factor 5),GO:0005737; GO:0007398; GO:0060644; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"cytoplasm; ectoderm development; mammary gland epithelial cell differentiation; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,,,,,,,,,ELF5_MOUSE,Mus musculus (Mouse),ectodermal cell fate commitment [GO:0001712]; ectoderm development [GO:0007398]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell differentiation [GO:0045596]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; somatic stem cell population maintenance [GO:0035019] comp139212_c1_seq1,1875,46.0267,0.53724552,95,264,,0,Q64487,Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48),GO:0007157; GO:0016021; GO:0030182; GO:0035335; GO:0050775; GO:0097105; GO:0004725,heterophilic cell-cell adhesion; integral to membrane; neuron differentiation; peptidyl-tyrosine dephosphorylation; positive regulation of dendrite morphogenesis; presynaptic membrane assembly; protein tyrosine phosphatase activity,PF00041;PF07679;PF00102;,0,CHOYP_PTPRF.5.6,,,,,,,PTPRD_MOUSE,Mus musculus (Mouse),heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of JAK-STAT cascade [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; presynaptic membrane assembly [GO:0097105]; regulation of immune response [GO:0050776] comp139215_c1_seq1,2204,39.6552,0.41445596,5,77,,2.00E-29,F7AEX0,UV-stimulated scaffold protein A,UV-stimulated scaffold protein A,GO:0000993; GO:0005694; GO:0016567; GO:0009411; GO:0006283,RNA polymerase II core binding; chromosome; protein ubiquitination; response to UV; transcription-coupled nucleotide-excision repair,PF09740;,,,,,,,,,UVSSA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283] comp139215_c1_seq3,2192,39.6898,0.41609754,8,65,,,,,,,,,9.00E-15,CHOYP_UVSSA.1.1,,,,,,,,, comp139219_c0_seq1,1810,37.6243,0.96329817,5,858,female>male,1.00E-126,Q495T6,"Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]","Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]",GO:0005794; GO:0005783; GO:0005615; GO:0016021; GO:0004222; GO:0006508; GO:0008270,Golgi apparatus; endoplasmic reticulum; extracellular space; integral to membrane; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01431;PF05649;,1.00E-55,CHOYP_NEP.1.2,,,,,,,MMEL1_HUMAN,Homo sapiens (Human), comp139221_c0_seq1,1282,40.0936,0.57009151,261,647,,2.00E-23,P79943,Histone RNA hairpin-binding protein (Histone stem-loop-binding protein 1),Histone RNA hairpin-binding protein (Histone stem-loop-binding protein 1),GO:0005737; GO:0003729; GO:0006397; GO:0005634,cytoplasm; mRNA binding; mRNA processing; nucleus,PF15247;,,,,,,,,,SLBP1_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397] comp139221_c1_seq1,259,43.6293,0.81505917,2,14,,4.00E-13,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp139221_c3_seq1,526,48.4791,0.62518957,6,33,,4.00E-26,A8WWR3,E3 ubiquitin-protein ligase hrd-like protein 1,E3 ubiquitin-protein ligase hrd-like protein 1,GO:0016021; GO:1901214; GO:0008270,integral to membrane; regulation of neuron death; zinc ion binding,PF02845;PF13639;,,,,,,,,,HRDL1_CAEBR,Caenorhabditis briggsae,proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of neuron death [GO:1901214] comp139221_c4_seq2,750,42.5333,0.33131526,4,5,,2.00E-97,Q9UKV5,E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78),E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78),GO:0030433; GO:0006928; GO:0030968; GO:0030176; GO:0051259; GO:0000209; GO:0004872; GO:0004842; GO:0008270,ER-associated protein catabolic process; cellular component movement; endoplasmic reticulum unfolded protein response; integral to endoplasmic reticulum membrane; protein oligomerization; protein polyubiquitination; receptor activity; ubiquitin-protein ligase activity; zinc ion binding,PF02845;PF13639;,3.00E-97,CHOYP_BRAFLDRAFT_217171.1.1,,,,,,,AMFR_HUMAN,Homo sapiens (Human),aging [GO:0007568]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; learning or memory [GO:0007611]; movement of cell or subcellular component [GO:0006928]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein oligomerization [GO:0051259]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] comp139225_c1_seq1,1584,42.298,0.38657155,548,3254,,2.00E-101,Q5ZK10,NSFL1 cofactor p47 (p97 cofactor p47),NSFL1 cofactor p47 (p97 cofactor p47),GO:0007030; GO:0005795; GO:0008289; GO:0061025; GO:0005634,Golgi organization; Golgi stack; lipid binding; membrane fusion; nucleus,PF08059;PF00789;,6.00E-28,CHOYP_NSF1C.1.1,,,,,,,NSF1C_CHICK,Gallus gallus (Chicken),Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; nuclear envelope reassembly [GO:0031468]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp139226_c0_seq1,2216,41.6968,0.5379149,129,411,,8.00E-162,Q91YJ5,"Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))","Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))",GO:0005525; GO:0006184; GO:0003924; GO:0001732; GO:0005739; GO:0006446; GO:0043024; GO:0032790; GO:0008135; GO:0003743,"GTP binding; GTP catabolic process; GTPase activity; formation of translation initiation complex; mitochondrion; regulation of translational initiation; ribosomal small subunit binding; ribosome disassembly; translation factor activity, nucleic acid binding; translation initiation factor activity",PF11987;,3.00E-33,CHOYP_MTIF2.1.1,,,,,,,IF2M_MOUSE,Mus musculus (Mouse),mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790] comp139227_c0_seq4,2951,37.4449,0.49702882,0,0,,,,,,,,,7.00E-18,CHOYP_RB505.1.1,,,,,,,,, comp139227_c0_seq6,1742,38.6338,0.43457833,0,0,,,,,,,,,4.00E-18,CHOYP_RB505.1.1,,,,,,,,, comp139230_c0_seq1,2445,39.3047,0.47892923,9,4,,4.00E-95,Q5PQZ3,Zinc transporter 9 (ZnT-9) (Solute carrier family 30 member 9),Zinc transporter 9 (ZnT-9) (Solute carrier family 30 member 9),GO:0016021; GO:0000166; GO:0005634; GO:0006355; GO:0006351; GO:0005385,"integral to membrane; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion transmembrane transporter activity",PF01545;,,,,,,,,,ZNT9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; zinc II ion transport [GO:0006829]" comp139230_c0_seq2,2425,39.299,0.49387919,6,6,,4.00E-95,Q5PQZ3,Zinc transporter 9 (ZnT-9) (Solute carrier family 30 member 9),Zinc transporter 9 (ZnT-9) (Solute carrier family 30 member 9),GO:0016021; GO:0000166; GO:0005634; GO:0006355; GO:0006351; GO:0005385,"integral to membrane; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion transmembrane transporter activity",PF01545;,,,,,,,,,ZNT9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; zinc II ion transport [GO:0006829]" comp139232_c0_seq1,1729,41.4691,0.5177929,770,2097,,4.00E-43,Q98943,Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],GO:0006915; GO:0004197; GO:0005622; GO:0006508; GO:0042981,apoptotic process; cysteine-type endopeptidase activity; intracellular; proteolysis; regulation of apoptotic process,PF00619;,,,,,,,,,CASP2_CHICK,Gallus gallus (Chicken),regulation of apoptotic process [GO:0042981] comp139234_c2_seq13,690,45.7971,0.52763041,0,0,,,,,,,,,1.00E-96,CHOYP_BRAFLDRAFT_68841.1.1,,,,,,,,, comp139234_c2_seq5,1150,45.3913,0.54698053,0,0,,3.00E-06,Q28CB1,TBC1 domain family member 2B,TBC1 domain family member 2B,GO:0005097; GO:0005543; GO:0032851,Rab GTPase activator activity; phospholipid binding; positive regulation of Rab GTPase activity,PF00169;PF00566;,,,,,,,,,TBD2B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp139234_c2_seq9,2288,46.1976,0.45575829,101,37,,2.00E-60,Q28CB1,TBC1 domain family member 2B,TBC1 domain family member 2B,GO:0005097; GO:0005543; GO:0032851,Rab GTPase activator activity; phospholipid binding; positive regulation of Rab GTPase activity,PF00169;PF00566;,0,CHOYP_BRAFLDRAFT_68841.1.1,,,,,,,TBD2B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp139235_c0_seq1,1002,37.2255,0.51204255,123,409,,6.00E-34,Q6DFN1,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3,GO:0005743; GO:0005634,mitochondrial inner membrane; nucleus,PF04430;,,,,,,,,,NDUF3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp139240_c0_seq1,1802,41.8979,0.3849111,381,0,,2.00E-21,Q95LL2,X-ray radiation resistance-associated protein 1 (Fragment),X-ray radiation resistance-associated protein 1 (Fragment),GO:0005737; GO:0005634; GO:0010165,cytoplasm; nucleus; response to X-ray,,,,,,,,,,XRRA1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),response to X-ray [GO:0010165] comp139240_c0_seq2,2910,42.8179,0.42553152,1134,46,,5.00E-75,Q6P2D8,X-ray radiation resistance-associated protein 1,X-ray radiation resistance-associated protein 1,GO:0005737; GO:0005634; GO:0010165,cytoplasm; nucleus; response to X-ray,,2.00E-75,CHOYP_LOC584905.1.1,,,,,,,XRRA1_HUMAN,Homo sapiens (Human),response to X-ray [GO:0010165] comp139241_c0_seq1,1920,38.75,0.56548248,32,24,,4.00E-105,Q9UNN5,FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A),FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A),GO:0031265; GO:0034098; GO:0006915; GO:0008219; GO:0007253; GO:0005829; GO:0031072; GO:0005635; GO:0005634; GO:0048471; GO:0043065; GO:0031334; GO:0043161; GO:0019901; GO:0019887; GO:0030155; GO:0042176; GO:0043130; GO:0031625,CD95 death-inducing signaling complex; Cdc48p-Npl4p-Ufd1p AAA ATPase complex; apoptotic process; cell death; cytoplasmic sequestering of NF-kappaB; cytosol; heat shock protein binding; nuclear envelope; nucleus; perinuclear region of cytoplasm; positive regulation of apoptotic process; positive regulation of protein complex assembly; proteasomal ubiquitin-dependent protein catabolic process; protein kinase binding; protein kinase regulator activity; regulation of cell adhesion; regulation of protein catabolic process; ubiquitin binding; ubiquitin protein ligase binding,PF00789;,1.00E-93,CHOYP_FAF1.1.1,,,,,,,FAF1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176] comp139241_c0_seq2,1740,37.4713,0.60226605,6,26,,7.00E-09,O00124,UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6),UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6),GO:0030433; GO:0030176; GO:0007338,ER-associated protein catabolic process; integral to endoplasmic reticulum membrane; single fertilization,PF00789;,3.00E-58,CHOYP_FAF1.1.1,,,,,,,UBXN8_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; single fertilization [GO:0007338] comp139241_c0_seq3,1125,36.9778,0.65672878,0,3,,6.00E-22,Q9UNN5,FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A),FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A),GO:0031265; GO:0034098; GO:0006915; GO:0008219; GO:0007253; GO:0005829; GO:0031072; GO:0005635; GO:0005634; GO:0048471; GO:0043065; GO:0031334; GO:0043161; GO:0019901; GO:0019887; GO:0030155; GO:0042176; GO:0043130; GO:0031625,CD95 death-inducing signaling complex; Cdc48p-Npl4p-Ufd1p AAA ATPase complex; apoptotic process; cell death; cytoplasmic sequestering of NF-kappaB; cytosol; heat shock protein binding; nuclear envelope; nucleus; perinuclear region of cytoplasm; positive regulation of apoptotic process; positive regulation of protein complex assembly; proteasomal ubiquitin-dependent protein catabolic process; protein kinase binding; protein kinase regulator activity; regulation of cell adhesion; regulation of protein catabolic process; ubiquitin binding; ubiquitin protein ligase binding,PF00789;,,,,,,,,,FAF1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176] comp139242_c0_seq6,1061,39.3025,0.57257435,8,0,,,,,,,,,4.00E-15,CHOYP_contig_006180,,,,,,,,, comp139244_c0_seq1,1181,41.4056,0.56487496,21,508,,2.00E-47,Q40784,Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Putative D-hexose-6-phosphate mutarotase) (Putative apospory-associated protein C),Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Putative D-hexose-6-phosphate mutarotase) (Putative apospory-associated protein C),GO:0030246; GO:0005975; GO:0047938,carbohydrate binding; carbohydrate metabolic process; glucose-6-phosphate 1-epimerase activity,PF01263;,4.00E-41,CHOYP_BRAFLDRAFT_113534.1.1,,,,,,,AAPC_CENCI,Cenchrus ciliaris (Buffelgrass) (Pennisetum ciliare),carbohydrate metabolic process [GO:0005975] comp139247_c0_seq1,2068,38.2012,0.71335098,230,1626,,3.00E-34,D3ZVR7,Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20),Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20),GO:0005829; GO:0016616; GO:0001516,"cytosol; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; prostaglandin biosynthetic process",PF13911;,1.00E-32,CHOYP_BRAFLDRAFT_96268.1.1,,,,,,,PGFS_RAT,Rattus norvegicus (Rat),prostaglandin biosynthetic process [GO:0001516] comp139248_c1_seq2,1646,32.8068,0.59170131,0,34,,,,,,,,,,,1.00E-14,ruditapes_c27956,,,,,,, comp139253_c2_seq1,784,40.8163,0.55214814,25,59,,2.00E-20,O89110,Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10],Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10],GO:0030690; GO:0006919; GO:0001525; GO:0071260; GO:0005813; GO:0097153; GO:0031264; GO:0008625; GO:0007507; GO:0097284; GO:0030225; GO:0005739; GO:0043124; GO:0060546; GO:0001841; GO:0043123; GO:2001238; GO:0045651; GO:0045862; GO:0051603; GO:0070243; GO:0034612,Noc1p-Noc2p complex; activation of cysteine-type endopeptidase activity involved in apoptotic process; angiogenesis; cellular response to mechanical stimulus; centrosome; cysteine-type endopeptidase activity involved in apoptotic process; death-inducing signaling complex; extrinsic apoptotic signaling pathway via death domain receptors; heart development; hepatocyte apoptotic process; macrophage differentiation; mitochondrion; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of necroptosis; neural tube formation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of macrophage differentiation; positive regulation of proteolysis; proteolysis involved in cellular protein catabolic process; regulation of thymocyte apoptotic process; response to tumor necrosis factor,PF01335;,,,,,,,,,CASP8_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of thymocyte apoptotic process [GO:0070243]; response to tumor necrosis factor [GO:0034612]; TRAIL-activated apoptotic signaling pathway [GO:0036462] comp139253_c2_seq3,871,45.3502,0.451978,2,12,,1.00E-83,Q76I76,Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L),Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L),GO:0003677; GO:0003779; GO:0030036; GO:0005737; GO:0005856; GO:0035335; GO:0004725; GO:0008138; GO:0008064; GO:0050770; GO:0010591,DNA binding; actin binding; actin cytoskeleton organization; cytoplasm; cytoskeleton; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of actin polymerization or depolymerization; regulation of axonogenesis; regulation of lamellipodium assembly,PF08766;PF00782;,5.00E-38,CHOYP_LOC100651687.1.1,,,,,,,SSH2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; protein dephosphorylation [GO:0006470]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of lamellipodium assembly [GO:0010591] comp139253_c2_seq4,1101,42.9609,0.44402967,0,0,,6.00E-81,Q76I76,Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L),Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L),GO:0003677; GO:0003779; GO:0030036; GO:0005737; GO:0005856; GO:0035335; GO:0004725; GO:0008138; GO:0008064; GO:0050770; GO:0010591,DNA binding; actin binding; actin cytoskeleton organization; cytoplasm; cytoskeleton; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of actin polymerization or depolymerization; regulation of axonogenesis; regulation of lamellipodium assembly,PF08766;PF00782;,,,,,,,,,SSH2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; protein dephosphorylation [GO:0006470]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of lamellipodium assembly [GO:0010591] comp139253_c2_seq6,870,43.1034,0.52072608,16,302,,3.00E-22,Q556Y8,Probable rhodanese domain-containing dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48),Probable rhodanese domain-containing dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48),GO:0035335; GO:0004725; GO:0008138,peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;PF00581;,,,,,,,,,DUSPR_DICDI,Dictyostelium discoideum (Slime mold),response to cisplatin [GO:0072718]; sorocarp development [GO:0030587] comp139254_c0_seq1,1350,47.7778,0.5331392,146,223,,4.00E-22,Q03188,Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7),Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7),GO:0003677; GO:0051301; GO:0005721; GO:0007059; GO:0000777; GO:0000780; GO:0005829; GO:0000776; GO:0051382; GO:0007067; GO:0000278,"DNA binding; cell division; centromeric heterochromatin; chromosome segregation; condensed chromosome kinetochore; condensed nuclear chromosome, centromeric region; cytosol; kinetochore; kinetochore assembly; mitosis; mitotic cell cycle",PF11699;PF15620;PF15622;,,,,,,,,,CENPC_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; CENP-A containing nucleosome assembly [GO:0034080]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; sister chromatid cohesion [GO:0007062] comp139255_c0_seq1,3431,35.6164,0.67403442,1104,4902,,,,,,,,,2.00E-19,CHOYP_PSIP1.1.1,,,,,,,,, comp139255_c1_seq1,1157,41.2273,0.55880082,47,150,,3.00E-32,Q66T72,PC4 and SFRS1-interacting protein (LEDGF/p75) (Lens epithelium-derived growth factor) (Transcription coactivator p75),PC4 and SFRS1-interacting protein (LEDGF/p75) (Lens epithelium-derived growth factor) (Transcription coactivator p75),GO:0001105; GO:0033613; GO:0003682; GO:0000395; GO:0005720; GO:0009408; GO:0006979; GO:0097100; GO:0035327,RNA polymerase II transcription coactivator activity; activating transcription factor binding; chromatin binding; mRNA 5'-splice site recognition; nuclear heterochromatin; response to heat; response to oxidative stress; supercoiled DNA binding; transcriptionally active chromatin,PF11467;PF00855;,,,,,,,,,PSIP1_FELCA,Felis catus (Cat) (Felis silvestris catus),mRNA 5'-splice site recognition [GO:0000395]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979] comp139255_c1_seq2,1163,40.7567,0.54023989,5,29,,5.00E-30,Q9Y3E1,Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma-derived growth factor 2) (HDGF-2),Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma-derived growth factor 2) (HDGF-2),GO:0008283; GO:0005737; GO:0005634,cell proliferation; cytoplasm; nucleus,PF00855;,2.00E-19,CHOYP_PSIP1.1.1,,,,,,,HDGR3_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; microtubule polymerization [GO:0046785]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175] comp139256_c0_seq1,3013,35.8779,0.56074811,411,2602,,4.00E-101,Q505F5,Leucine-rich repeat-containing protein 47,Leucine-rich repeat-containing protein 47,GO:0003723; GO:0004826,RNA binding; phenylalanine-tRNA ligase activity,PF03483;PF12799;PF13855;,,,7.00E-47,ruditapes_c7551,,,,,LRC47_MOUSE,Mus musculus (Mouse), comp139256_c0_seq2,1032,43.7984,0.52759002,0,14,,5.00E-84,Q8N1G4,Leucine-rich repeat-containing protein 47,Leucine-rich repeat-containing protein 47,GO:0003723; GO:0004826,RNA binding; phenylalanine-tRNA ligase activity,PF03483;PF13855;,1.00E-53,CHOYP_LOC100370672.1.1,,,,,,,LRC47_HUMAN,Homo sapiens (Human), comp139257_c0_seq1,2676,46.4126,0.54498482,324,459,,1.00E-34,Q5VWG9,Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140),Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140),GO:0051457; GO:0043433; GO:0000122; GO:0005669; GO:0006351; GO:0008270,"maintenance of protein location in nucleus; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; transcription factor TFIID complex; transcription, DNA-dependent; zinc ion binding",PF07524;PF00628;,,,,,,,,,TAF3_HUMAN,Homo sapiens (Human),maintenance of protein location in nucleus [GO:0051457]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp139258_c0_seq10,491,46.4358,0.87775404,0,115,,2.00E-06,Q9LMN7,Wall-associated receptor kinase 5 (EC 2.7.11.-),Wall-associated receptor kinase 5 (EC 2.7.11.-),GO:0005524; GO:0005509; GO:0016021; GO:0030247; GO:0004674,ATP binding; calcium ion binding; integral to membrane; polysaccharide binding; protein serine/threonine kinase activity,PF07645;PF13947;PF07714;,,,,,,,,,WAK5_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell surface receptor signaling pathway [GO:0007166] comp139258_c0_seq11,384,40.8854,1.09963783,0,59,,7.00E-07,Q8BNA6,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,3.00E-12,CHOYP_LOC575027.5.6,,,,,,,FAT3_MOUSE,Mus musculus (Mouse),cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842] comp139258_c0_seq12,343,42.8571,1.08775628,0,173,,2.00E-07,Q62059,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0007507; GO:0005540; GO:0005578; GO:0001657,calcium ion binding; carbohydrate binding; cell adhesion; heart development; hyaluronic acid binding; proteinaceous extracellular matrix; ureteric bud development,PF00008;PF00059;PF00084;PF07686;PF00193;,8.00E-12,CHOYP_LOC100374755.2.3,,,,,,,CSPG2_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; glial cell migration [GO:0008347]; heart development [GO:0007507]; osteoblast differentiation [GO:0001649]; regulation of phosphoprotein phosphatase activity [GO:0043666]; skeletal system development [GO:0001501]; ureteric bud development [GO:0001657] comp139258_c0_seq18,301,47.8405,1.04181345,0,168,,1.00E-10,P46530,Neurogenic locus notch homolog protein 1,Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)],GO:0007219; GO:0005509; GO:0007368; GO:0031017; GO:0021986; GO:0055016; GO:0016021; GO:0001840; GO:0048936; GO:0048337; GO:0004872; GO:0042663; GO:0048259; GO:0006355; GO:0021523; GO:0001756; GO:0021531; GO:0006351,"Notch signaling pathway; calcium ion binding; determination of left/right symmetry; exocrine pancreas development; habenula development; hypochord development; integral to membrane; neural plate development; peripheral nervous system neuron axonogenesis; positive regulation of mesodermal cell fate specification; receptor activity; regulation of endodermal cell fate specification; regulation of receptor-mediated endocytosis; regulation of transcription, DNA-dependent; somatic motor neuron differentiation; somitogenesis; spinal cord radial glial cell differentiation; transcription, DNA-dependent",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal aorta development [GO:0035907]; exocrine pancreas development [GO:0031017]; generation of neurons [GO:0048699]; habenula development [GO:0021986]; hematopoietic progenitor cell differentiation [GO:0002244]; hypochord development [GO:0055016]; negative regulation of neurogenesis [GO:0050768]; neural plate development [GO:0001840]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; positive regulation of mesodermal cell fate specification [GO:0048337]; regulation of endodermal cell fate specification [GO:0042663]; regulation of receptor-mediated endocytosis [GO:0048259]; regulation of transcription, DNA-templated [GO:0006355]; somatic motor neuron differentiation [GO:0021523]; somitogenesis [GO:0001756]; spinal cord radial glial cell differentiation [GO:0021531]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron differentiation [GO:0021514]" comp139258_c0_seq2,308,45.7792,1.01729467,0,64,,2.00E-18,P98133,Fibrillin-1 (MP340),Fibrillin-1 (MP340) [Cleaved into: Asprosin],GO:0005509; GO:0005201; GO:0005578,calcium ion binding; extracellular matrix structural constituent; proteinaceous extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN1_BOVIN,Bos taurus (Bovine),activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287] comp139259_c0_seq1,857,42.7071,0.43159012,98,509,,1.00E-96,Q5ZIG2,Pre-mRNA-splicing factor SLU7,Pre-mRNA-splicing factor SLU7,GO:0008380; GO:0006397; GO:0003676; GO:0005681; GO:0008270,RNA splicing; mRNA processing; nucleic acid binding; spliceosomal complex; zinc ion binding,PF11708;,,,,,,,,,SLU7_CHICK,Gallus gallus (Chicken),"mRNA processing [GO:0006397]; RNA splicing, via transesterification reactions [GO:0000375]" comp139259_c1_seq1,1460,39.863,0.36259867,8,0,,7.00E-61,Q9SHY8,Pre-mRNA-splicing factor SLU7-A,Pre-mRNA-splicing factor SLU7-A,GO:0008380; GO:0006397; GO:0008284; GO:0003727; GO:0005681; GO:0008270,RNA splicing; mRNA processing; positive regulation of cell proliferation; single-stranded RNA binding; spliceosomal complex; zinc ion binding,PF11708;,3.00E-81,CHOYP_LOC100374345.1.2,,,,,,,SLU7A_ARATH,Arabidopsis thaliana (Mouse-ear cress),"mRNA processing [GO:0006397]; positive regulation of cell proliferation [GO:0008284]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" comp139259_c1_seq2,1461,39.1513,0.37694517,8,13,,5.00E-69,P0CR52,Pre-mRNA-splicing factor SLU7,Pre-mRNA-splicing factor SLU7,GO:0008380; GO:0006397; GO:0003676; GO:0005681; GO:0008270,RNA splicing; mRNA processing; nucleic acid binding; spliceosomal complex; zinc ion binding,PF11708;,,,,,,,,,SLU7_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),"mRNA processing [GO:0006397]; RNA splicing, via transesterification reactions [GO:0000375]" comp139259_c2_seq1,2298,40.9051,0.35456033,34,440,,9.00E-18,P17035,Zinc finger protein 28 (Zinc finger protein KOX24),Zinc finger protein 28 (Zinc finger protein KOX24),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZNF28_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139263_c0_seq1,1771,43.1395,0.37646587,88,31,,2.00E-102,Q80TA9,Ectopic P granules protein 5 homolog,Ectopic P granules protein 5 homolog,GO:0006914,autophagy,,7.00E-15,CHOYP_EPG5.1.1,,,,,,,EPG5_MOUSE,Mus musculus (Mouse),autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; endocytic recycling [GO:0032456] comp139263_c2_seq1,2065,43.2446,0.32174873,0,0,,1.00E-11,A5D8S0,Centrosomal protein kizuna (Polo-like kinase 1 substrate 1),Centrosomal protein kizuna (Polo-like kinase 1 substrate 1),GO:0005813; GO:0005737; GO:0007051,centrosome; cytoplasm; spindle organization,,,,,,,,,,KIZ_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),spindle organization [GO:0007051] comp139263_c2_seq4,1673,41.3628,0.36433966,0,0,,,,,,,,,,,4.00E-34,ruditapes_c8903,,,,,,, comp139263_c2_seq9,1912,42.7824,0.34407103,0,0,,2.00E-11,A5D8S0,Centrosomal protein kizuna (Polo-like kinase 1 substrate 1),Centrosomal protein kizuna (Polo-like kinase 1 substrate 1),GO:0005813; GO:0005737; GO:0007051,centrosome; cytoplasm; spindle organization,,,,,,,,,,KIZ_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),spindle organization [GO:0007051] comp139267_c0_seq1,2722,42.432,0.44162863,5000,11954,,2.00E-63,Q8R081,Heterogeneous nuclear ribonucleoprotein L (hnRNP L),Heterogeneous nuclear ribonucleoprotein L (hnRNP L),GO:0003723; GO:0005737; GO:0006397; GO:0005654; GO:0000166; GO:0045120; GO:0030529; GO:0044212,RNA binding; cytoplasm; mRNA processing; nucleoplasm; nucleotide binding; pronucleus; ribonucleoprotein complex; transcription regulatory region DNA binding,PF00076;,3.00E-22,CHOYP_HNRPL.1.1,,,,,,,HNRPL_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp139272_c0_seq1,1311,41.3425,0.49480418,30,760,,1.00E-139,O83041,Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),GO:0004177; GO:0005737; GO:0006508,aminopeptidase activity; cytoplasm; proteolysis,PF00561;,5.00E-117,CHOYP_CAOG_02976.2.2,,,,,,,PIP_PLEBO,Leptolyngbya boryana (Plectonema boryanum), comp139275_c0_seq5,1322,31.4675,0.71449745,1,0,,1.00E-44,Q66I67,Intraflagellar transport protein 20 homolog,Intraflagellar transport protein 20 homolog,GO:0005794; GO:0005930; GO:0042073; GO:0005932,Golgi apparatus; axoneme; intraflagellar transport; microtubule basal body,PF14931;,2.00E-95,CHOYP_LOC100371443.1.1,,,,,,,IFT20_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),centrosome localization [GO:0051642]; cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067] comp139276_c0_seq1,1366,34.1142,0.80599973,5905,79552,,,,,,,,,,,6.00E-50,ruditapes_c32323,,,,,,, comp139276_c1_seq1,1110,48.9189,0.74276925,2630,42622,,0,Q04467,"Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)","Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)",GO:0006103; GO:0051287; GO:0006097; GO:0004450; GO:0006102; GO:0000287; GO:0005743; GO:0006099,2-oxoglutarate metabolic process; NAD binding; glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; isocitrate metabolic process; magnesium ion binding; mitochondrial inner membrane; tricarboxylic acid cycle,PF00180;,0,CHOYP_BRAFLDRAFT_115608.1.1,1.00E-44,ruditapes_c8987,2.00E-180,AY551096.p.cg.6,4,,IDHP_BOVIN,Bos taurus (Bovine),2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099] comp139277_c0_seq1,3421,42.5022,0.67642861,835,78,,0,Q4GZT3,Polycystin-2 (Polycystic kidney disease 2 protein homolog),Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2),GO:0007259; GO:0035904; GO:0045180; GO:0009925; GO:0001658; GO:0005262; GO:0005509; GO:0048763; GO:0007050; GO:0005911; GO:0071498; GO:0071464; GO:0071470; GO:0042994; GO:0050982; GO:0003127; GO:0071910; GO:0001892; GO:0031941; GO:0001947; GO:0071458; GO:0071556; GO:0005887; GO:0030027; GO:0016020; GO:0072177; GO:0072284; GO:0072218; GO:0072214; GO:0072219; GO:0072235; GO:0072075; GO:0035502; GO:0072208; GO:0005932; GO:0072686; GO:0031512; GO:2000134; GO:0060315; GO:0021915; GO:0031513; GO:0060674; GO:0002133; GO:0071158; GO:0031659; GO:0031587; GO:0045429; GO:0045944; GO:0005267; GO:0030814; GO:0090279; GO:0042127; GO:0051209; GO:0061441; GO:0061333; GO:0021510; GO:0005245; GO:0005248,"JAK-STAT cascade; aorta development; basal cortex; basal plasma membrane; branching involved in ureteric bud morphogenesis; calcium channel activity; calcium ion binding; calcium-induced calcium release activity; cell cycle arrest; cell-cell junction; cellular response to fluid shear stress; cellular response to hydrostatic pressure; cellular response to osmotic stress; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; detection of nodal flow; determination of liver left/right asymmetry; embryonic placenta development; filamentous actin; heart looping; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; lamellipodium; membrane; mesonephric duct development; metanephric S-shaped body morphogenesis; metanephric ascending thin limb development; metanephric cortex development; metanephric cortical collecting duct development; metanephric distal tubule development; metanephric mesenchyme development; metanephric part of ureteric bud development; metanephric smooth muscle tissue development; microtubule basal body; mitotic spindle; motile primary cilium; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of ryanodine-sensitive calcium-release channel activity; neural tube development; nonmotile primary cilium; placenta blood vessel development; polycystin complex; positive regulation of cell cycle arrest; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of nitric oxide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; potassium channel activity; regulation of cAMP metabolic process; regulation of calcium ion import; regulation of cell proliferation; release of sequestered calcium ion into cytosol; renal artery morphogenesis; renal tubule morphogenesis; spinal cord development; voltage-gated calcium channel activity; voltage-gated sodium channel activity",PF08016;,0,CHOYP_PKD2.1.3,,,,,,,PKD2_BOVIN,Bos taurus (Bovine),"aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]" comp139279_c1_seq10,407,37.5921,0.4223628,92,244,,,,,,,,,,,5.00E-13,ruditapes_c21652,,,,,,, comp139281_c0_seq1,713,39.9719,0.77700984,0,15,,3.00E-39,Q9VYV5,"Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)","Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)",GO:0032580; GO:0036071; GO:0046921; GO:0008424; GO:0016021; GO:0033578,Golgi cisterna membrane; N-glycan fucosylation; alpha-(1->6)-fucosyltransferase activity; glycoprotein 6-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation in Golgi,,,,,,,,,,FUT8_DROME,Drosophila melanogaster (Fruit fly),GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] comp139281_c0_seq2,2855,34.4658,0.97133602,3,2280,female>male,5.00E-141,Q9WTS2,"Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)","Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)",GO:0032580; GO:0036071; GO:0046921; GO:0016477; GO:0008424; GO:0016021; GO:0007229; GO:0033578; GO:0043112; GO:0007585; GO:0007179,Golgi cisterna membrane; N-glycan fucosylation; alpha-(1->6)-fucosyltransferase activity; cell migration; glycoprotein 6-alpha-L-fucosyltransferase activity; integral to membrane; integrin-mediated signaling pathway; protein glycosylation in Golgi; receptor metabolic process; respiratory gaseous exchange; transforming growth factor beta receptor signaling pathway,PF14604;,,,,,,,,,FUT8_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; GDP-L-fucose metabolic process [GO:0046368]; integrin-mediated signaling pathway [GO:0007229]; N-glycan fucosylation [GO:0036071]; N-glycan processing [GO:0006491]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor metabolic process [GO:0043112]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; respiratory gaseous exchange [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp139282_c0_seq1,877,39.2246,0.59358492,0,0,,2.00E-09,Q9JKJ9,24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.13.99) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase),24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase),GO:0033782; GO:0006699; GO:0030573; GO:0006707; GO:0007586; GO:0005789; GO:0020037; GO:0043231; GO:0005506; GO:0008396; GO:0008387,24-hydroxycholesterol 7alpha-hydroxylase activity; bile acid biosynthetic process; bile acid catabolic process; cholesterol catabolic process; digestion; endoplasmic reticulum membrane; heme binding; intracellular membrane-bounded organelle; iron ion binding; oxysterol 7-alpha-hydroxylase activity; steroid 7-alpha-hydroxylase activity,PF00067;,,,,,,,,,CP39A_MOUSE,Mus musculus (Mouse),bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586] comp139282_c0_seq2,943,38.7063,0.56689951,4,0,,7.00E-56,P79152,Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment),Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP3AJ_CAPAE,Capra hircus aegagrus (Wild goat) (Capra aegagrus), comp139282_c0_seq4,1019,39.0579,0.54101891,2,32,,4.00E-58,Q64409,Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17),Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP3AH_CAVPO,Cavia porcellus (Guinea pig), comp139287_c2_seq1,981,38.0224,0.59815586,235,1659,,2.00E-43,P97615,"Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)","Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)",GO:0045454; GO:0031669; GO:0030425; GO:0006662; GO:0005739; GO:0043025; GO:0005730; GO:0015035; GO:0048678; GO:0042493; GO:0009749; GO:0009725; GO:0001666; GO:0007584; GO:0014070; GO:0006979,cell redox homeostasis; cellular response to nutrient levels; dendrite; glycerol ether metabolic process; mitochondrion; neuronal cell body; nucleolus; protein disulfide oxidoreductase activity; response to axon injury; response to drug; response to glucose stimulus; response to hormone stimulus; response to hypoxia; response to nutrient; response to organic cyclic compound; response to oxidative stress,PF00085;,,,,,,,,,THIOM_RAT,Rattus norvegicus (Rat),cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; protein folding [GO:0006457]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfate assimilation [GO:0000103] comp139288_c0_seq1,1286,38.647,0.4172072,45,136,,2.00E-106,Q8WVM0,"Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)","Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)",GO:0003677; GO:0042645; GO:0000179; GO:0031167; GO:0006355; GO:0006351,"DNA binding; mitochondrial nucleoid; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00398;,,,,,,,,,TFB1M_HUMAN,Homo sapiens (Human),"mitochondrion organization [GO:0007005]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139288_c0_seq2,1360,37.2794,0.42478175,9,61,,1.00E-112,Q28HM1,"Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)","Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)",GO:0003677; GO:0005739; GO:0000179; GO:0031167; GO:0006355; GO:0006351,"DNA binding; mitochondrion; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00398;,2.00E-13,CHOYP_TFB1M.1.1,,,,,,,TFB1M_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139289_c0_seq1,1477,45.5653,0.50011599,182,490,,0,Q91YR7,Pre-mRNA-processing factor 6 (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein),Pre-mRNA-processing factor 6 (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein),GO:0003723; GO:0006403; GO:0071001; GO:0046540; GO:0005682; GO:0050681; GO:0071013; GO:0000398; GO:0016607; GO:0005634; GO:0045944; GO:0043021; GO:0003713,"RNA binding; RNA localization; U4/U6 snRNP; U4/U6 x U5 tri-snRNP complex; U5 snRNP; androgen receptor binding; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nuclear speck; nucleus; positive regulation of transcription from RNA polymerase II promoter; ribonucleoprotein complex binding; transcription coactivator activity",PF06424;,,,,,,,,,PRP6_MOUSE,Mus musculus (Mouse),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; RNA localization [GO:0006403]; spliceosomal tri-snRNP complex assembly [GO:0000244] comp139289_c0_seq4,1212,46.6172,0.4233805,83,183,,6.00E-41,P19735,Pre-mRNA-splicing factor 6,Pre-mRNA-splicing factor 6,GO:0046540; GO:0000398; GO:0005681,"U4/U6 x U5 tri-snRNP complex; mRNA splicing, via spliceosome; spliceosomal complex",PF06424;,0,CHOYP_PRP6.1.2,,,,,,,PRP6_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp139291_c0_seq1,2626,42.2696,0.72324327,9,22,,8.00E-06,Q9HAZ1,Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4),Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4),GO:0005524; GO:0005634; GO:0046777; GO:0004674; GO:0004712; GO:0004713; GO:0043484,ATP binding; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; regulation of RNA splicing,PF00069;,0,CHOYP_LOC100870649.2.2,,,,,,,CLK4_HUMAN,Homo sapiens (Human),protein autophosphorylation [GO:0046777]; regulation of RNA splicing [GO:0043484] comp139291_c0_seq2,2411,42.5964,0.6645392,0,0,,0,Q08CW1,Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled-like kinase 2),Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled-like kinase 2),GO:0005524; GO:0005634; GO:0004674,ATP binding; nucleus; protein serine/threonine kinase activity,PF00069;,0,CHOYP_LOC100870649.2.2,3.00E-88,ruditapes_c8443,,,,,TLK2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp139293_c0_seq3,1589,36.5639,0.45756511,227,1763,,2.00E-23,Q9NWZ8,Gem-associated protein 8 (Gemin-8) (Protein FAM51A1),Gem-associated protein 8 (Gemin-8) (Protein FAM51A1),GO:0097504; GO:0032797; GO:0005737; GO:0005634; GO:0005681; GO:0000387,Gemini of coiled bodies; SMN complex; cytoplasm; nucleus; spliceosomal complex; spliceosomal snRNP assembly,,8.00E-20,CHOYP_GEMIN8.1.1,,,,,,,GEMI8_HUMAN,Homo sapiens (Human),spliceosomal snRNP assembly [GO:0000387] comp139307_c1_seq10,1614,29.6159,0.51067213,0,0,,,,,,,,,2.00E-47,CHOYP_POLR2L.2.2.3,,,,,,,,, comp139307_c1_seq13,1759,29.9034,0.48503149,1,75,,1.00E-36,P62876,"DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RPB10 homolog)","DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RPB10 homolog)",GO:0003677; GO:0005665; GO:0003899; GO:0006366; GO:0008270,"DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; transcription from RNA polymerase II promoter; zinc ion binding",PF01194;,,,,,,,,,RPAB5_MOUSE,Mus musculus (Mouse),transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360] comp139307_c1_seq7,1597,29.9311,0.47746785,0,0,,,,,,,,,2.00E-47,CHOYP_POLR2L.2.2.3,,,,,,,,, comp139307_c1_seq9,1732,29.9654,0.4914626,0,0,,1.00E-36,P62876,"DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RPB10 homolog)","DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RPB10 homolog)",GO:0003677; GO:0005665; GO:0003899; GO:0006366; GO:0008270,"DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; transcription from RNA polymerase II promoter; zinc ion binding",PF01194;,2.00E-47,CHOYP_POLR2L.2.2.3,1.00E-41,ruditapes_c16944,,,,,RPAB5_MOUSE,Mus musculus (Mouse),transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360] comp139308_c0_seq1,1606,39.7883,0.96153959,117,4,,3.00E-65,A0LMC1,Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase),Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase),GO:0000287; GO:0019700; GO:0050194,magnesium ion binding; organic phosphonate catabolic process; phosphonoacetaldehyde hydrolase activity,PF13419;,,,,,,,,,PHNX_SYNFM,Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB),organic phosphonate catabolic process [GO:0019700] comp139308_c0_seq2,1565,39.9361,0.93156961,94,21,,2.00E-65,A0LMC1,Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase),Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase),GO:0000287; GO:0019700; GO:0050194,magnesium ion binding; organic phosphonate catabolic process; phosphonoacetaldehyde hydrolase activity,PF13419;,2.00E-66,CHOYP_PMAR_PMAR019172.1.1,5.00E-115,ruditapes2_c3913,,,,,PHNX_SYNFM,Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB),organic phosphonate catabolic process [GO:0019700] comp139309_c0_seq3,1406,37.7667,0.4637046,1157,161,,4.00E-11,Q9NUD7,Uncharacterized protein C20orf96,Uncharacterized protein C20orf96,,,PF15397;,2.00E-78,CHOYP_LOC100370141.1.1,,,,,,,CT096_HUMAN,Homo sapiens (Human), comp139310_c0_seq1,1175,39.6596,0.98437571,170,831,,1.00E-44,Q5TC84,Opioid growth factor receptor-like protein 1,Opioid growth factor receptor-like protein 1,GO:0016020; GO:0004872,membrane; receptor activity,PF04664;,,,,,,,,,OGRL1_HUMAN,Homo sapiens (Human), comp139311_c0_seq1,1872,48.5043,0.37506299,154,395,,2.00E-170,Q6DFB8,Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),GO:0055087; GO:0005634; GO:0035327,Ski complex; nucleus; transcriptionally active chromatin,PF13181;,8.00E-40,CHOYP_LOC100378002.1.1,,,,,,,TTC37_XENLA,Xenopus laevis (African clawed frog), comp139312_c0_seq1,1431,37.1768,0.44831534,347,1198,,4.00E-28,P38126,Pachytene checkpoint protein 2,Pachytene checkpoint protein 2,GO:0005524; GO:0016887; GO:0005694; GO:0042138; GO:0051598; GO:0005730; GO:0007131,ATP binding; ATPase activity; chromosome; meiotic DNA double-strand break formation; meiotic recombination checkpoint; nucleolus; reciprocal meiotic recombination,PF00004;,,,,,,,,,PCH2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),meiotic DNA double-strand break formation [GO:0042138]; meiotic recombination checkpoint [GO:0051598]; reciprocal meiotic recombination [GO:0007131] comp139312_c0_seq2,855,42.1053,0.66180199,124,258,,2.00E-87,Q15645,Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13),Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13),GO:0005524; GO:0006302; GO:0007144; GO:0001673; GO:0007141; GO:0017111; GO:0005634; GO:0001556; GO:0048477; GO:0007131; GO:0007286; GO:0007283; GO:0007130; GO:0003712; GO:0006366,ATP binding; double-strand break repair; female meiosis I; male germ cell nucleus; male meiosis I; nucleoside-triphosphatase activity; nucleus; oocyte maturation; oogenesis; reciprocal meiotic recombination; spermatid development; spermatogenesis; synaptonemal complex assembly; transcription cofactor activity; transcription from RNA polymerase II promoter,PF00004;,1.00E-78,CHOYP_PCH2.1.1,,,,,,,PCH2_HUMAN,Homo sapiens (Human),double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; oocyte maturation [GO:0001556]; oogenesis [GO:0048477]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; transcription from RNA polymerase II promoter [GO:0006366] comp139315_c0_seq2,2804,37.0899,0.43815253,0,0,,0,Q05086,Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54),Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54),GO:0030521; GO:0007420; GO:0005737; GO:0005829; GO:0019048; GO:0005634; GO:0001541; GO:0014068; GO:0045944; GO:0060736; GO:0000502; GO:0070936; GO:0042787; GO:0035037; GO:0003713; GO:0004842,androgen receptor signaling pathway; brain development; cytoplasm; cytosol; modulation by virus of host morphology or physiology; nucleus; ovarian follicle development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of transcription from RNA polymerase II promoter; prostate gland growth; proteasome complex; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sperm entry; transcription coactivator activity; ubiquitin-protein ligase activity,PF16558;PF00632;,8.00E-137,CHOYP_EF2.4.5,,,,,,,UBE3A_HUMAN,Homo sapiens (Human),androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032] comp139315_c0_seq8,2761,37.0156,0.42611626,0,0,,0,Q05086,Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54),Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54),GO:0030521; GO:0007420; GO:0005737; GO:0005829; GO:0019048; GO:0005634; GO:0001541; GO:0014068; GO:0045944; GO:0060736; GO:0000502; GO:0070936; GO:0042787; GO:0035037; GO:0003713; GO:0004842,androgen receptor signaling pathway; brain development; cytoplasm; cytosol; modulation by virus of host morphology or physiology; nucleus; ovarian follicle development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of transcription from RNA polymerase II promoter; prostate gland growth; proteasome complex; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sperm entry; transcription coactivator activity; ubiquitin-protein ligase activity,PF16558;PF00632;,8.00E-137,CHOYP_EF2.4.5,,,,,,,UBE3A_HUMAN,Homo sapiens (Human),androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032] comp139316_c1_seq3,319,48.2759,0.2754848,49,0,,4.00E-06,Q27409,Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1),Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1),GO:0005576,extracellular region,,,,,,,,,,FP1_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp139319_c0_seq1,1061,36.1923,0.41887627,980,3416,,7.00E-10,Q9NX63,"Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial",MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3),GO:0001227; GO:0007007; GO:0008053; GO:0005743; GO:0005634; GO:0019902; GO:0032947,RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; inner mitochondrial membrane organization; mitochondrial fusion; mitochondrial inner membrane; nucleus; phosphatase binding; protein complex scaffold,PF05300;,,,1.00E-18,ruditapes_lrc38466,,,,,CHCH3_HUMAN,Homo sapiens (Human),"cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp139323_c0_seq1,1449,39.2685,0.75410522,244,2014,,3.00E-42,O46503,Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.-) (Sulfotransferase 1C1),Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.-) (Sulfotransferase 1C1),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,4.00E-11,CHOYP_ST1A1.1.1,7.00E-12,ruditapes_c20565,,,,,ST1C2_RABIT,Oryctolagus cuniculus (Rabbit),sulfation [GO:0051923] comp139327_c1_seq3,2386,45.9346,0.42310247,0,0,,0,Q96N67,Dedicator of cytokinesis protein 7,Dedicator of cytokinesis protein 7,GO:0048365; GO:0032863; GO:0030424; GO:0007409; GO:0045178; GO:0045200; GO:0030426; GO:0005085; GO:0000226; GO:0043473; GO:0033138; GO:0007264,Rac GTPase binding; activation of Rac GTPase activity; axon; axonogenesis; basal part of cell; establishment of neuroblast polarity; growth cone; guanyl-nucleotide exchange factor activity; microtubule cytoskeleton organization; pigmentation; positive regulation of peptidyl-serine phosphorylation; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;,4.00E-165,CHOYP_DOCK7.1.3,,,,,,,DOCK7_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] comp139331_c0_seq1,2350,41.5745,1.05429563,812,11082,,0,Q7ZXY0,Inositol-3-phosphate synthase 1-A (IPS 1-A) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase A) (MI-1-P synthase A) (MIP synthase A),Inositol-3-phosphate synthase 1-A (IPS 1-A) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase A) (MI-1-P synthase A) (MIP synthase A),GO:0005737; GO:0006021; GO:0004512; GO:0008654,cytoplasm; inositol biosynthetic process; inositol-3-phosphate synthase activity; phospholipid biosynthetic process,PF01658;PF07994;,0,CHOYP_INO1A.1.1,2.00E-34,ruditapes_c10932,,,,,INO1A_XENLA,Xenopus laevis (African clawed frog),inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654] comp139333_c0_seq1,1784,41.9283,0.54495118,925,7601,,4.00E-136,Q08DG6,Cytochrome c oxidase assembly protein COX15 homolog,Cytochrome c oxidase assembly protein COX15 homolog,GO:0006784; GO:0016021; GO:0005743; GO:0016627; GO:0008535,"heme a biosynthetic process; integral to membrane; mitochondrial inner membrane; oxidoreductase activity, acting on the CH-CH group of donors; respiratory chain complex IV assembly",PF02628;,4.00E-87,CHOYP_LOC101026589.1.1,,,,,,,COX15_BOVIN,Bos taurus (Bovine),heme a biosynthetic process [GO:0006784]; respiratory chain complex IV assembly [GO:0008535] comp139334_c0_seq1,2214,40.8311,0.75868407,0,0,,1.00E-101,Q98TX3,Programmed cell death protein 4 (Protein I11/6),Programmed cell death protein 4 (Protein I11/6),GO:0003723; GO:0007569; GO:0005829; GO:0043508; GO:0045892; GO:0005634,"RNA binding; cell aging; cytosol; negative regulation of JUN kinase activity; negative regulation of transcription, DNA-dependent; nucleus",PF02847;,,,,,,,,,PDCD4_CHICK,Gallus gallus (Chicken),"cell aging [GO:0007569]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of transcription, DNA-templated [GO:0045892]" comp139334_c0_seq2,1999,41.1706,0.77810624,0,0,,,,,,,,,7.00E-79,CHOYP_LOC100370909.1.1,,,,,,,,, comp139334_c0_seq4,2074,38.4282,0.6486657,0,0,,,,,,,,,4.00E-88,CHOYP_MKS3.1.1,,,,,,,,, comp139334_c0_seq6,2056,38.4728,0.63895513,0,0,,2.00E-95,Q5HYA8,Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67),Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67),GO:0030433; GO:0036038; GO:0005813; GO:0042384; GO:0060170; GO:0030659; GO:0005789; GO:0016021; GO:0005932; GO:0010826,ER-associated protein catabolic process; TCTN-B9D complex; centrosome; cilium assembly; cilium membrane; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; integral to membrane; microtubule basal body; negative regulation of centrosome duplication,PF09773;,,,,,,,,,MKS3_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of centrosome duplication [GO:0010826] comp139334_c0_seq7,1124,42.8826,0.73912021,0,0,,,,,,,,,7.00E-76,CHOYP_MKS3.1.1,,,,,,,,, comp139334_c0_seq8,2113,41.4103,0.77284377,0,0,,4.00E-102,Q98TX3,Programmed cell death protein 4 (Protein I11/6),Programmed cell death protein 4 (Protein I11/6),GO:0003723; GO:0007569; GO:0005829; GO:0043508; GO:0045892; GO:0005634,"RNA binding; cell aging; cytosol; negative regulation of JUN kinase activity; negative regulation of transcription, DNA-dependent; nucleus",PF02847;,7.00E-79,CHOYP_LOC100370909.1.1,,,,,,,PDCD4_CHICK,Gallus gallus (Chicken),"cell aging [GO:0007569]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of transcription, DNA-templated [GO:0045892]" comp139334_c1_seq2,1071,43.5107,0.43470445,30,43,,1.00E-56,Q5HYA8,Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67),Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67),GO:0030433; GO:0036038; GO:0005813; GO:0042384; GO:0060170; GO:0030659; GO:0005789; GO:0016021; GO:0005932; GO:0010826,ER-associated protein catabolic process; TCTN-B9D complex; centrosome; cilium assembly; cilium membrane; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; integral to membrane; microtubule basal body; negative regulation of centrosome duplication,PF09773;,,,,,,,,,MKS3_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of centrosome duplication [GO:0010826] comp139338_c0_seq2,2662,44.4778,0.53256508,179,890,,9.00E-74,Q2NL57,Ubiquitin carboxyl-terminal hydrolase 10-A (EC 3.4.19.12) (Deubiquitinating enzyme 10-A) (Ubiquitin thioesterase 10-A) (Ubiquitin-specific-processing protease 10-A),Ubiquitin carboxyl-terminal hydrolase 10-A (EC 3.4.19.12) (Deubiquitinating enzyme 10-A) (Ubiquitin thioesterase 10-A) (Ubiquitin-specific-processing protease 10-A),GO:0030330; GO:0006281; GO:0006914; GO:0004197; GO:0005769; GO:0044325; GO:0005634; GO:0002039; GO:0016579; GO:0010506; GO:0004221; GO:0006511; GO:0004843,"DNA damage response, signal transduction by p53 class mediator; DNA repair; autophagy; cysteine-type endopeptidase activity; early endosome; ion channel binding; nucleus; p53 binding; protein deubiquitination; regulation of autophagy; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity",PF00443;,5.00E-44,CHOYP_UBP10.1.1,,,,,,,UB10A_XENLA,Xenopus laevis (African clawed frog),"autophagy [GO:0006914]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp139340_c0_seq2,1484,46.2938,0.65635389,224,368,,0,Q9UJT0,Tubulin epsilon chain (Epsilon-tubulin),Tubulin epsilon chain (Epsilon-tubulin),GO:0005525; GO:0003924; GO:0007098; GO:0005874; GO:0000242; GO:0051258; GO:0005200,GTP binding; GTPase activity; centrosome cycle; microtubule; pericentriolar material; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC100374494.1.1,,,,,,,TBE_HUMAN,Homo sapiens (Human),centrosome cycle [GO:0007098] comp139341_c0_seq1,861,45.4123,0.32530099,14,51,,9.00E-32,Q641W3,Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1),Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1),GO:0000492; GO:0022626; GO:0046872; GO:0016363; GO:0005730; GO:0005726; GO:0045944; GO:0070761; GO:0048786; GO:0030515; GO:0008023,box C/D snoRNP assembly; cytosolic ribosome; metal ion binding; nuclear matrix; nucleolus; perichromatin fibrils; positive regulation of transcription from RNA polymerase II promoter; pre-snoRNP complex; presynaptic active zone; snoRNA binding; transcription elongation factor complex,PF10453;,,,,,,,,,NUFP1_RAT,Rattus norvegicus (Rat),box C/D snoRNP assembly [GO:0000492]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein oligomerization [GO:0051259] comp139341_c0_seq2,879,45.165,0.34366095,56,186,,6.00E-30,Q9UHK0,Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1),Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1),GO:0003677; GO:0003723; GO:0006396; GO:0000492; GO:0022626; GO:0046872; GO:0016363; GO:0005730; GO:0005726; GO:0045944; GO:0070761; GO:0048786; GO:0008023,DNA binding; RNA binding; RNA processing; box C/D snoRNP assembly; cytosolic ribosome; metal ion binding; nuclear matrix; nucleolus; perichromatin fibrils; positive regulation of transcription from RNA polymerase II promoter; pre-snoRNP complex; presynaptic active zone; transcription elongation factor complex,PF10453;,2.00E-25,CHOYP_NUFIP1.1.1,,,,,,,NUFP1_HUMAN,Homo sapiens (Human),box C/D snoRNP assembly [GO:0000492]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein oligomerization [GO:0051259]; RNA processing [GO:0006396] comp139346_c0_seq1,1073,39.6086,0.74643595,52,76,,4.00E-17,O96006,Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog),Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog),GO:0003677; GO:0046872; GO:0000228; GO:0004803,DNA binding; metal ion binding; nuclear chromosome; transposase activity,PF05699;PF02892;,,,,,,,,,ZBED1_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp139350_c0_seq2,795,43.1447,0.5145626,0,0,,4.00E-36,P56536,Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) (Fragment),Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) (Fragment),GO:0005524; GO:0005737; GO:0005871; GO:0051028; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; mRNA transport; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,2.00E-11,CHOYP_LOC100875479.2.2,,,,,,,KIF5C_RAT,Rattus norvegicus (Rat),axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mRNA transport [GO:0051028]; protein localization [GO:0008104] comp139350_c0_seq3,1030,43.2039,0.47928334,33,50,,2.00E-136,Q9I869,Kinesin-like protein KIF22-A (Chromokinesin kid-A) (Xkid-A),Kinesin-like protein KIF22-A (Chromokinesin kid-A) (Xkid-A),GO:0005524; GO:0003677; GO:0006281; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005634,ATP binding; DNA binding; DNA repair; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; nucleus,PF00225;,3.00E-11,CHOYP_LOC100875479.2.2,,,,,,,KF22A_XENLA,Xenopus laevis (African clawed frog),microtubule-based movement [GO:0007018] comp139353_c0_seq6,1009,36.0753,0.43443572,26,74,,7.00E-06,Q8N187,Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24),Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24),GO:0003677; GO:0035865; GO:0005730; GO:0005654; GO:0005634; GO:0061400; GO:0003700; GO:0006351,"DNA binding; cellular response to potassium ion; nucleolus; nucleoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF15299;,,,,,,,,,AL2S8_HUMAN,Homo sapiens (Human),cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400] comp139356_c1_seq1,3029,41.0366,0.58561427,11,0,,0,O88600,Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein),Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein),GO:0005524; GO:0005829; GO:0001822; GO:0005811; GO:0043392; GO:0043066; GO:0010629; GO:0001933; GO:0005634; GO:0045766; GO:0010628; GO:0032092; GO:0009408,ATP binding; cytosol; kidney development; lipid particle; negative regulation of DNA binding; negative regulation of apoptotic process; negative regulation of gene expression; negative regulation of protein phosphorylation; nucleus; positive regulation of angiogenesis; positive regulation of gene expression; positive regulation of protein binding; response to heat,PF00012;,2.00E-94,CHOYP_HS105.1.1,,,,,,,HSP74_RAT,Rattus norvegicus (Rat),kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of protein binding [GO:0032092]; response to heat [GO:0009408] comp139356_c1_seq3,2567,40.67,0.45360119,0,0,,0,O88600,Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein),Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein),GO:0005524; GO:0005829; GO:0001822; GO:0005811; GO:0043392; GO:0043066; GO:0010629; GO:0001933; GO:0005634; GO:0045766; GO:0010628; GO:0032092; GO:0009408,ATP binding; cytosol; kidney development; lipid particle; negative regulation of DNA binding; negative regulation of apoptotic process; negative regulation of gene expression; negative regulation of protein phosphorylation; nucleus; positive regulation of angiogenesis; positive regulation of gene expression; positive regulation of protein binding; response to heat,PF00012;,2.00E-94,CHOYP_HS105.1.1,,,,,,,HSP74_RAT,Rattus norvegicus (Rat),kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of protein binding [GO:0032092]; response to heat [GO:0009408] comp139356_c1_seq5,968,41.3223,0.77199332,3,6,,1.00E-39,P48741,Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B),Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B),GO:0005524; GO:0006986,ATP binding; response to unfolded protein,PF00012;,,,,,,,,,HSP77_HUMAN,Homo sapiens (Human), comp139357_c3_seq2,2260,37.3451,0.47987275,115,190,,2.00E-87,Q5RED7,"Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase)","Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase)",GO:0005524; GO:0003951; GO:0047620; GO:0046513; GO:0001729; GO:0004143; GO:0046486; GO:0031966; GO:0007205,ATP binding; NAD+ kinase activity; acylglycerol kinase activity; ceramide biosynthetic process; ceramide kinase activity; diacylglycerol kinase activity; glycerolipid metabolic process; mitochondrial membrane; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00781;,1.00E-44,CHOYP_AGK.1.1,,,,,,,AGK_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486] comp139359_c1_seq1,1470,43.8095,0.39985722,102,201,,5.00E-148,Q7ZVP1,Protein Jade-3 (PHD finger protein 16),Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16),GO:0008270,zinc ion binding,PF10513;,1.00E-144,CHOYP_BRAFLDRAFT_123304.1.1,,,,,,,JADE3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139360_c1_seq1,1096,44.8905,0.9638768,13,741,,1.00E-12,Q6B9X6,Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),GO:0005524; GO:0005516; GO:0031164; GO:0000331; GO:0005829; GO:0000281; GO:0031038; GO:0018209; GO:0018107; GO:0048471; GO:0004674; GO:0031156; GO:0031288,ATP binding; calmodulin binding; contractile vacuolar membrane; contractile vacuole; cytosol; mitotic cytokinesis; myosin II filament organization; peptidyl-serine modification; peptidyl-threonine phosphorylation; perinuclear region of cytoplasm; protein serine/threonine kinase activity; regulation of sorocarp development; sorocarp morphogenesis,PF02816;,,,,,,,,,VWKA_DICDI,Dictyostelium discoideum (Slime mold),contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288] comp139361_c1_seq1,1110,28.7387,0.52446935,737,974,,,,,,,,,,,1.00E-13,ruditapes_c5444,,,,,,, comp139363_c0_seq1,4180,41.1962,0.47440962,146,124,,0,Q9ES00,Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Ufd2a),Ubiquitin conjugation factor E4 B (EC 6.3.2.-) (Ubiquitin fusion degradation protein 2),GO:0005737; GO:0008626; GO:0006457; GO:0042787; GO:0009411; GO:0000151; GO:0034450; GO:0051082,cytoplasm; granzyme-mediated apoptotic signaling pathway; protein folding; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to UV; ubiquitin ligase complex; ubiquitin-ubiquitin ligase activity; unfolded protein binding,PF04564;PF10408;,,,,,,,,,UBE4B_MOUSE,Mus musculus (Mouse),cellular protein catabolic process [GO:0044257]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; neuron projection development [GO:0031175]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein folding [GO:0006457]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp139363_c0_seq2,2617,39.5491,0.51060709,0,0,,0,Q9ES00,Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Ufd2a),Ubiquitin conjugation factor E4 B (EC 6.3.2.-) (Ubiquitin fusion degradation protein 2),GO:0005737; GO:0008626; GO:0006457; GO:0042787; GO:0009411; GO:0000151; GO:0034450; GO:0051082,cytoplasm; granzyme-mediated apoptotic signaling pathway; protein folding; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to UV; ubiquitin ligase complex; ubiquitin-ubiquitin ligase activity; unfolded protein binding,PF04564;PF10408;,3.00E-154,CHOYP_UBE4B.1.1,,,,,,,UBE4B_MOUSE,Mus musculus (Mouse),cellular protein catabolic process [GO:0044257]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; neuron projection development [GO:0031175]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein folding [GO:0006457]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp139367_c0_seq1,446,49.7758,1.06674335,0,93,,4.00E-37,Q8K078,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0006811; GO:0005886; GO:0005215,integral to membrane; ion transport; plasma membrane; transporter activity,PF07648;PF03137;,,,,,,,,,SO4A1_MOUSE,Mus musculus (Mouse),organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp139369_c0_seq1,1219,37.4077,0.47067933,3,5,,1.00E-31,Q99J09,Methylosome protein 50 (MEP-50) (WD repeat-containing protein 77),Methylosome protein 50 (MEP-50) (WD repeat-containing protein 77),GO:0005794; GO:0005737; GO:0030374; GO:0060770; GO:0005634; GO:0008284; GO:0006357; GO:0060528,Golgi apparatus; cytoplasm; ligand-dependent nuclear receptor transcription coactivator activity; negative regulation of epithelial cell proliferation involved in prostate gland development; nucleus; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development,PF00400;,,,,,,,,,MEP50_MOUSE,Mus musculus (Mouse),negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528] comp139369_c0_seq2,1192,37.9195,0.44504469,10,32,,2.00E-08,Q7ZYQ6,DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1),DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1),GO:0080008; GO:0005730; GO:0016567; GO:0006364; GO:0030529,Cul4-RING ubiquitin ligase complex; nucleolus; protein ubiquitination; rRNA processing; ribonucleoprotein complex,PF04158;PF00400;,,,,,,,,,DCA13_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567]; rRNA processing [GO:0006364] comp139369_c2_seq1,269,36.803,0.55374022,3,4,,3.00E-18,Q9NYT6,Zinc finger protein 226,Zinc finger protein 226,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN226_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139370_c0_seq1,1803,45.0361,1.00568533,0,1142,,1.00E-167,Q9NQ79,Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC),Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC),GO:0005509; GO:0005578,calcium ion binding; proteinaceous extracellular matrix,PF07645;PF07593;,6.00E-41,CHOYP_LOC100716602.1.1,,,,,,,CRAC1_HUMAN,Homo sapiens (Human),axonal fasciculation [GO:0007413]; negative regulation of receptor binding [GO:1900121]; olfactory bulb development [GO:0021772] comp139371_c0_seq1,4861,40.7735,0.38638215,117,37,,8.00E-17,Q92628,Uncharacterized protein KIAA0232,Uncharacterized protein KIAA0232,GO:0005524,ATP binding,PF15376;,,,,,,,,,K0232_HUMAN,Homo sapiens (Human), comp139371_c0_seq2,1354,38.7001,0.30057692,0,0,,,,,,,,,3.00E-18,CHOYP_KIAA0232.1.1,,,,,,,,, comp139371_c0_seq4,3409,40.5984,0.37135471,2,0,,,,,,,,,8.00E-18,CHOYP_KIAA0232.1.1,,,,,,,,, comp139373_c0_seq1,3372,43.3571,0.47059915,395,73,,0,Q8BXR9,Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6),Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6),GO:0006869; GO:0005543,lipid transport; phospholipid binding,PF01237;,1.00E-141,CHOYP_OSBL6.1.1,,,,,,,OSBL6_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869] comp139373_c1_seq1,1095,38.4475,0.69303039,2,11,,9.00E-55,Q8IYX4,"Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)","Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)",GO:0017091; GO:0005737; GO:0007281; GO:0007275; GO:0060965; GO:0000166; GO:0005634,AU-rich element binding; cytoplasm; germ cell development; multicellular organismal development; negative regulation of gene silencing by miRNA; nucleotide binding; nucleus,PF00076;,,,,,,,,,DND1_HUMAN,Homo sapiens (Human),germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; negative regulation of gene silencing by miRNA [GO:0060965] comp139373_c1_seq2,2128,41.3534,0.4215256,319,10,,1.00E-12,A0JM51,CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5),CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus,PF00076;,,,,,,,,,CELF5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397] comp139373_c1_seq3,1422,43.2489,0.49027288,0,0,,1.00E-160,Q5R9H4,APOBEC1 complementation factor (APOBEC1-stimulating protein),APOBEC1 complementation factor (APOBEC1-stimulating protein),GO:0030895; GO:0005737; GO:0005783; GO:0006397; GO:0000166; GO:0050821; GO:0003727,apolipoprotein B mRNA editing enzyme complex; cytoplasm; endoplasmic reticulum; mRNA processing; nucleotide binding; protein stabilization; single-stranded RNA binding,PF00076;,2.00E-104,CHOYP_A1CF.1.2,,,,,,,A1CF_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; protein stabilization [GO:0050821] comp139376_c0_seq1,2971,44.968,0.38693143,0,6,,5.00E-70,Q9VR91,Probable E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),Probable E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0005814; GO:0005737; GO:0020037; GO:0046872; GO:0005634; GO:0042787; GO:0004842,centriole; cytoplasm; heme binding; metal ion binding; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF11515;PF00173;PF00632;PF06701;PF00415;,2.00E-76,CHOYP_HERC1.2.2,,,,,,,HERC2_DROME,Drosophila melanogaster (Fruit fly),protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp139376_c0_seq2,8041,43.1911,0.33806353,361,41,,0,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,,,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp139376_c0_seq3,3311,44.2465,0.37732385,2,0,,8.00E-62,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,5.00E-77,CHOYP_HERC1.2.2,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp139376_c0_seq4,6003,43.5949,0.34408689,0,0,,0,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,,,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp139377_c0_seq1,3759,44.2139,0.51858534,186,550,,2.00E-175,Q23356,Serine/threonine-protein kinase mig-15 (EC 2.7.11.1) (Abnormal cell migration protein 15),Serine/threonine-protein kinase mig-15 (EC 2.7.11.1) (Abnormal cell migration protein 15),GO:0005524; GO:0010171; GO:0033563; GO:0002119; GO:0004674; GO:0000003; GO:0004871; GO:0005083,ATP binding; body morphogenesis; dorsal/ventral axon guidance; nematode larval development; protein serine/threonine kinase activity; reproduction; signal transducer activity; small GTPase regulator activity,PF00780;PF00069;,0,CHOYP_LOC100650469.2.2,,,,,,,MIG15_CAEEL,Caenorhabditis elegans,"body morphogenesis [GO:0010171]; dorsal/ventral axon guidance [GO:0033563]; nematode larval development [GO:0002119]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of synaptic transmission, GABAergic [GO:0032228]; reproduction [GO:0000003]" comp139377_c0_seq2,2005,45.3367,0.51490714,3,0,,2.00E-176,Q9JM52,Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6),Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6),GO:0005524; GO:0030424; GO:0030054; GO:0005737; GO:0030425; GO:0048813; GO:0007243; GO:0045060; GO:0014069; GO:0045211; GO:0046777; GO:0004674; GO:2000311; GO:0006950; GO:0005083; GO:0007268,ATP binding; axon; cell junction; cytoplasm; dendrite; dendrite morphogenesis; intracellular protein kinase cascade; negative thymic T cell selection; postsynaptic density; postsynaptic membrane; protein autophosphorylation; protein serine/threonine kinase activity; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; response to stress; small GTPase regulator activity; synaptic transmission,PF00780;PF00069;,0,CHOYP_LOC100650469.2.2,,,,,,,MINK1_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; chemical synaptic transmission [GO:0007268]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; negative thymic T cell selection [GO:0045060]; positive regulation of JNK cascade [GO:0046330]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell migration [GO:0030334]; response to stress [GO:0006950] comp139377_c0_seq3,924,41.9913,0.65261121,2,0,,2.00E-26,Q86CS2,Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1),Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1),GO:0005524; GO:0048102; GO:0006995; GO:0005737; GO:0016236; GO:0070265; GO:0034045; GO:0046777; GO:0004674; GO:0015031; GO:0031288; GO:0030435,ATP binding; autophagic cell death; cellular response to nitrogen starvation; cytoplasm; macroautophagy; necrotic cell death; pre-autophagosomal structure membrane; protein autophosphorylation; protein serine/threonine kinase activity; protein transport; sorocarp morphogenesis; sporulation resulting in formation of a cellular spore,PF12063;PF00069;,,,,,,,,,ATG1_DICDI,Dictyostelium discoideum (Slime mold),autophagic cell death [GO:0048102]; cellular response to nitrogen starvation [GO:0006995]; defense response to bacterium [GO:0042742]; exit from host cell [GO:0035891]; macroautophagy [GO:0016236]; necrotic cell death [GO:0070265]; protein autophosphorylation [GO:0046777]; protein transport [GO:0015031]; response to bacterium [GO:0009617]; sorocarp development [GO:0030587]; sorocarp morphogenesis [GO:0031288]; sporulation resulting in formation of a cellular spore [GO:0030435] comp139378_c1_seq1,2643,40.2951,0.46028644,13,68,,1.00E-57,Q10190,Large subunit GTPase 1 (EC 3.6.1.-),Large subunit GTPase 1 (EC 3.6.1.-),GO:0005525; GO:0005829; GO:0016787; GO:0015031; GO:0000054,GTP binding; cytosol; hydrolase activity; protein transport; ribosomal subunit export from nucleus,PF01926;,,,,,,,,,LSG1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein transport [GO:0015031]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] comp139378_c1_seq2,2629,40.2054,0.46440797,0,10,,3.00E-92,Q6NY89,Large subunit GTPase 1 homolog (EC 3.6.1.-),Large subunit GTPase 1 homolog (EC 3.6.1.-),GO:0015030; GO:0005525; GO:0003924; GO:0005829; GO:0005783; GO:0051168; GO:0015031; GO:0042254,Cajal body; GTP binding; GTPase activity; cytosol; endoplasmic reticulum; nuclear export; protein transport; ribosome biogenesis,PF01926;,2.00E-35,CHOYP_LSG1.1.1,,,,,,,LSG1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nuclear export [GO:0051168]; protein transport [GO:0015031]; ribosome biogenesis [GO:0042254] comp139380_c0_seq1,2140,45.1869,0.36365268,128,62,,0,Q5M868,Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2),Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2),GO:0000139; GO:0008422; GO:0008206; GO:0021954; GO:0005789; GO:0004348; GO:0006680; GO:0016139; GO:0016021,Golgi membrane; beta-glucosidase activity; bile acid metabolic process; central nervous system neuron development; endoplasmic reticulum membrane; glucosylceramidase activity; glucosylceramide catabolic process; glycoside catabolic process; integral to membrane,PF04685;PF12215;,8.00E-129,CHOYP_GBA2.2.2,,,,,,,GBA2_RAT,Rattus norvegicus (Rat),bile acid metabolic process [GO:0008206]; central nervous system neuron development [GO:0021954]; glucosylceramide catabolic process [GO:0006680]; glycoside catabolic process [GO:0016139] comp139380_c0_seq2,872,43.578,0.49149935,3,0,,,,,,,,,2.00E-69,CHOYP_GBA2.1.2,,,,,,,,, comp139381_c0_seq1,2497,34.4814,0.36717301,19,48,,1.00E-57,Q14108,Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36),Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36),GO:0007155; GO:0005887; GO:0043202; GO:0005765; GO:0006622; GO:0004872,cell adhesion; integral to plasma membrane; lysosomal lumen; lysosomal membrane; protein targeting to lysosome; receptor activity,PF01130;,,,,,,,,,SCRB2_HUMAN,Homo sapiens (Human),protein targeting to lysosome [GO:0006622] comp139381_c0_seq3,2349,33.5888,0.30406154,3,0,,5.00E-30,D2A0H5,Sensory neuron membrane protein 1,Sensory neuron membrane protein 1,GO:0007155; GO:0016021; GO:0005886; GO:0050896; GO:0007608,cell adhesion; integral to membrane; plasma membrane; response to stimulus; sensory perception of smell,PF01130;,,,,,,,,,SNMP1_TRICA,Tribolium castaneum (Red flour beetle),response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] comp139381_c0_seq4,2169,33.4255,0.3662448,6,17,,2.00E-36,Q14108,Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36),Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36),GO:0007155; GO:0005887; GO:0043202; GO:0005765; GO:0006622; GO:0004872,cell adhesion; integral to plasma membrane; lysosomal lumen; lysosomal membrane; protein targeting to lysosome; receptor activity,PF01130;,,,,,,,,,SCRB2_HUMAN,Homo sapiens (Human),protein targeting to lysosome [GO:0006622] comp139387_c0_seq1,991,37.6387,0.50642694,10,121,,2.00E-11,Q9Y673,Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog),Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog),GO:0007368; GO:0006488; GO:0004581; GO:0005789; GO:0016021; GO:0004576; GO:0043687; GO:0018279,determination of left/right symmetry; dolichol-linked oligosaccharide biosynthetic process; dolichyl-phosphate beta-glucosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; oligosaccharyl transferase activity; post-translational protein modification; protein N-linked glycosylation via asparagine,PF00535;,2.00E-127,CHOYP_DPM1.1.1,,,,,,,ALG5_HUMAN,Homo sapiens (Human),determination of left/right symmetry [GO:0007368]; dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269] comp139387_c0_seq2,940,37.0213,0.56106264,3,58,,3.00E-145,O60762,Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) (Dolichol-phosphate mannose synthase) (DPM synthase) (Dolichyl-phosphate beta-D-mannosyltransferase) (Mannose-P-dolichol synthase) (MPD synthase),Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1),GO:0006501; GO:0019673; GO:0006506; GO:0043178; GO:0019348; GO:0006488; GO:0033185; GO:0004582; GO:0004169; GO:0005789; GO:0005537; GO:0018279; GO:0035269,C-terminal protein lipidation; GDP-mannose metabolic process; GPI anchor biosynthetic process; alcohol binding; dolichol metabolic process; dolichol-linked oligosaccharide biosynthetic process; dolichol-phosphate-mannose synthase complex; dolichyl-phosphate beta-D-mannosyltransferase activity; dolichyl-phosphate-mannose-protein mannosyltransferase activity; endoplasmic reticulum membrane; mannose binding; protein N-linked glycosylation via asparagine; protein O-linked mannosylation,PF00535;,,,,,,,,,DPM1_HUMAN,Homo sapiens (Human),dolichol metabolic process [GO:0019348]; GDP-mannose metabolic process [GO:0019673]; GPI anchor biosynthetic process [GO:0006506]; protein mannosylation [GO:0035268]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269] comp139388_c0_seq1,1102,39.2015,0.42885876,118,513,,3.00E-36,Q96HR3,Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25),Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25),GO:0001104; GO:0030521; GO:0030374; GO:0016592; GO:0045893; GO:0004872; GO:0019827; GO:0046966; GO:0006367; GO:0042809,"RNA polymerase II transcription cofactor activity; androgen receptor signaling pathway; ligand-dependent nuclear receptor transcription coactivator activity; mediator complex; positive regulation of transcription, DNA-dependent; receptor activity; stem cell maintenance; thyroid hormone receptor binding; transcription initiation from RNA polymerase II promoter; vitamin D receptor binding",PF11315;,8.00E-18,CHOYP_contig_032576,5.00E-18,ruditapes_c24683,,,,,MED30_HUMAN,Homo sapiens (Human),"androgen receptor signaling pathway [GO:0030521]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; positive regulation of transcription, DNA-templated [GO:0045893]; stem cell population maintenance [GO:0019827]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp139392_c0_seq1,2828,42.5389,0.41476813,205,50,,5.00E-77,Q8C428,Transmembrane channel-like protein 7,Transmembrane channel-like protein 7,GO:0016021; GO:0006811,integral to membrane; ion transport,PF07810;,3.00E-40,CHOYP_LOC100743792.1.1,,,,,,,TMC7_MOUSE,Mus musculus (Mouse),ion transport [GO:0006811] comp139393_c0_seq1,2776,36.8516,0.61120172,781,1655,,0,Q60972,Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48),Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48),GO:0033186; GO:0006260; GO:0008094; GO:0035098; GO:0016589; GO:0016581; GO:0007049; GO:0031497; GO:0006338; GO:0006355; GO:0006351,"CAF-1 complex; DNA replication; DNA-dependent ATPase activity; ESC/E(Z) complex; NURF complex; NuRD complex; cell cycle; chromatin assembly; chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12265;PF00400;,,,,,,,,,RBBP4_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA replication [GO:0006260]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; transcription, DNA-templated [GO:0006351]" comp139393_c0_seq2,2792,36.8553,0.59684505,189,981,,0,Q60972,Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48),Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48),GO:0033186; GO:0006260; GO:0008094; GO:0035098; GO:0016589; GO:0016581; GO:0007049; GO:0031497; GO:0006338; GO:0006355; GO:0006351,"CAF-1 complex; DNA replication; DNA-dependent ATPase activity; ESC/E(Z) complex; NURF complex; NuRD complex; cell cycle; chromatin assembly; chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12265;PF00400;,0,CHOYP_RBBP4.1.1,2.00E-90,ruditapes_c17191,0,FP089861.p.cg.6,9,,RBBP4_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA replication [GO:0006260]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; transcription, DNA-templated [GO:0006351]" comp139394_c2_seq1,1821,35.9692,0.33062108,377,432,,2.00E-28,Q8AVX1,G kinase-anchoring protein 1-B,G kinase-anchoring protein 1-B,GO:0005794; GO:0007165,Golgi apparatus; signal transduction,,6.00E-73,CHOYP_GKAP1.1.1,4.00E-47,ruditapes_c29598,,,,,GKP1B_XENLA,Xenopus laevis (African clawed frog),signal transduction [GO:0007165] comp139395_c0_seq3,1706,35.4631,0.58023046,0,0,,4.00E-38,Q8CHQ0,F-box only protein 4,F-box only protein 4,GO:0019005; GO:0031146; GO:0005737; GO:0031398; GO:0000209; GO:0000723; GO:0004842,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cytoplasm; positive regulation of protein ubiquitination; protein polyubiquitination; telomere maintenance; ubiquitin-protein ligase activity,PF12937;,,,,,,,,,FBX4_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cellular homeostasis [GO:0019725]; cellular response to ionizing radiation [GO:0071479]; common myeloid progenitor cell proliferation [GO:0035726]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of protein localization to nucleus [GO:1900181]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; posttranscriptional regulation of gene expression [GO:0010608]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511] comp139395_c0_seq4,1690,35.3846,0.58849106,0,0,,4.00E-38,Q8CHQ0,F-box only protein 4,F-box only protein 4,GO:0019005; GO:0031146; GO:0005737; GO:0031398; GO:0000209; GO:0000723; GO:0004842,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cytoplasm; positive regulation of protein ubiquitination; protein polyubiquitination; telomere maintenance; ubiquitin-protein ligase activity,PF12937;,2.00E-20,CHOYP_NEMVEDRAFT_V1G210610.2.2,,,,,,,FBX4_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cellular homeostasis [GO:0019725]; cellular response to ionizing radiation [GO:0071479]; common myeloid progenitor cell proliferation [GO:0035726]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of protein localization to nucleus [GO:1900181]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; posttranscriptional regulation of gene expression [GO:0010608]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511] comp139396_c1_seq1,1568,36.6071,0.51734771,0,0,,2.00E-40,P25325,3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2),3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2),GO:0016784; GO:0030054; GO:0009440; GO:0070814; GO:0005739; GO:0043005; GO:0009636; GO:0045202; GO:0004792,3-mercaptopyruvate sulfurtransferase activity; cell junction; cyanate catabolic process; hydrogen sulfide biosynthetic process; mitochondrion; neuron projection; response to toxic substance; synapse; thiosulfate sulfurtransferase activity,PF00581;,,,,,,,,,THTM_HUMAN,Homo sapiens (Human),cyanate catabolic process [GO:0009440]; hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; response to toxic substance [GO:0009636]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346] comp139396_c1_seq3,1601,36.4147,0.53134349,0,0,,9.00E-39,P46635,Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),GO:0008097; GO:0005759; GO:0035928; GO:0004792,5S rRNA binding; mitochondrial matrix; rRNA import into mitochondrion; thiosulfate sulfurtransferase activity,PF00581;,,,,,,,,,THTR_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029] comp139398_c0_seq1,1833,39.9891,0.5191212,0,9,,2.00E-19,Q5RF15,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF12796;PF07714;,,,,,,,,,TNI3K_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp139398_c0_seq2,1880,39.6277,0.52911026,16,31,,1.00E-16,Q08DV6,Ankyrin repeat and SOCS box protein 3 (ASB-3),Ankyrin repeat and SOCS box protein 3 (ASB-3),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB3_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556] comp139398_c0_seq3,1310,38.855,0.58798364,0,4,,4.00E-15,Q9H2K2,Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-like protein) (Tankyrase-related protein),Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-like protein) (Tankyrase-related protein),GO:0000139; GO:0003950; GO:0016055; GO:0046872; GO:0035264; GO:0000784; GO:0005635; GO:0000242; GO:0048471; GO:0090263; GO:0032212; GO:0070213; GO:0070198; GO:0000209; GO:0040014,"Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; metal ion binding; multicellular organism growth; nuclear chromosome, telomeric region; nuclear envelope; pericentriolar material; perinuclear region of cytoplasm; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of telomere maintenance via telomerase; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein polyubiquitination; regulation of multicellular organism growth",PF00023;PF12796;PF00644;PF07647;,,,,,,,,,TNKS2_HUMAN,Homo sapiens (Human),"multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]" comp139402_c3_seq1,1632,38.3578,0.38942243,13,30,,4.00E-14,Q54FL3,Putative mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20),Putative mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20),GO:0001104; GO:0016592; GO:0006366,RNA polymerase II transcription cofactor activity; mediator complex; transcription from RNA polymerase II promoter,PF08612;,,,,,,,,,MED20_DICDI,Dictyostelium discoideum (Slime mold),regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366] comp139402_c3_seq2,1647,38.2514,0.38794741,5,56,,4.00E-61,Q17LR9,Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20),Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF08612;,3.00E-31,CHOYP_DHX57.2.2,,,,,,,MED20_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"transcription, DNA-templated [GO:0006351]" comp139409_c0_seq2,574,44.7735,0.64486177,0,6,,2.00E-31,Q54YC4,Alpha-mannosidase D (EC 3.2.1.24),Alpha-mannosidase D (EC 3.2.1.24),GO:0004559; GO:0030246; GO:0005975; GO:0016021; GO:0008270,alpha-mannosidase activity; carbohydrate binding; carbohydrate metabolic process; integral to membrane; zinc ion binding,PF09261;PF01074;,,,,,,,,,MAND_DICDI,Dictyostelium discoideum (Slime mold),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp139409_c0_seq3,589,45.3311,0.53297353,0,22,,1.00E-86,Q60HE9,Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B),Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B),GO:0004559; GO:0030246; GO:0005764; GO:0006013; GO:0008270,alpha-mannosidase activity; carbohydrate binding; lysosome; mannose metabolic process; zinc ion binding,PF09261;PF01074;PF07748;,4.00E-76,CHOYP_LOC100176799.1.1,,,,,,,MA2B1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),mannose metabolic process [GO:0006013] comp139409_c1_seq1,1107,36.9467,0.45118366,0,15,,,,,,,,,,,3.00E-28,ruditapes_c10367,,,,,,, comp139409_c3_seq1,629,45.151,0.47202917,6,81,,9.00E-15,Q1ZXI8,Alpha-mannosidase E (EC 3.2.1.24),Alpha-mannosidase E (EC 3.2.1.24),GO:0004559; GO:0030246; GO:0005975; GO:0016021; GO:0008270,alpha-mannosidase activity; carbohydrate binding; carbohydrate metabolic process; integral to membrane; zinc ion binding,PF09261;PF01074;,,,,,,,,,MANE_DICDI,Dictyostelium discoideum (Slime mold),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp139410_c0_seq1,848,43.9858,0.2686558,1193,5557,,9.00E-138,Q9R1P4,Proteasome subunit alpha type-1 (EC 3.4.25.1) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain),Proteasome subunit alpha type-1 (EC 3.4.25.1) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain),GO:0005829; GO:0001530; GO:0002862; GO:0005634; GO:0005839; GO:0019773; GO:0004298; GO:0006511,"cytosol; lipopolysaccharide binding; negative regulation of inflammatory response to antigenic stimulus; nucleus; proteasome core complex; proteasome core complex, alpha-subunit complex; threonine-type endopeptidase activity; ubiquitin-dependent protein catabolic process",PF00227;PF10584;,1.00E-152,CHOYP_PSA1.1.1,,,,,,,PSA1_MOUSE,Mus musculus (Mouse),"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp139410_c1_seq1,867,33.4487,0.1654202,1935,6764,,,,,,,,,,,1.00E-11,ruditapes2_c556,,,,,,, comp139411_c0_seq1,1958,36.5169,0.60134608,37,870,,4.00E-11,A8KBY2,Transcription factor IIIB 50 kDa subunit (B-related factor 2) (BRF-2),Transcription factor IIIB 50 kDa subunit (B-related factor 2) (BRF-2),GO:0006352; GO:0005634; GO:0006355; GO:0008270,"DNA-dependent transcription, initiation; nucleus; regulation of transcription, DNA-dependent; zinc ion binding",PF08271;,,,,,,,,,BRF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]" comp139412_c0_seq3,2560,42.1875,0.56231847,4,0,,1.00E-08,Q8INR6,"Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (dDOT1L) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Protein grappa)","Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (dDOT1L) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Protein grappa)",GO:0006348; GO:0048096; GO:0031151; GO:0035097; GO:0046331; GO:2000637,chromatin silencing at telomere; chromatin-mediated maintenance of transcription; histone methyltransferase activity (H3-K79 specific); histone methyltransferase complex; lateral inhibition; positive regulation of gene silencing by miRNA,PF08123;,,,,,,,,,DOT1L_DROME,Drosophila melanogaster (Fruit fly),chromatin-mediated maintenance of transcription [GO:0048096]; chromatin silencing [GO:0006342]; chromatin silencing at telomere [GO:0006348]; histone H3-K79 methylation [GO:0034729]; histone methylation [GO:0016571]; lateral inhibition [GO:0046331]; positive regulation of gene silencing by miRNA [GO:2000637]; regulation of cell cycle [GO:0051726] comp139412_c1_seq2,1044,43.4866,0.67217043,100,137,,4.00E-140,Q8TEK3,"Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)","Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)",GO:0003677; GO:0018024; GO:0005634; GO:0046425; GO:2000677,DNA binding; histone-lysine N-methyltransferase activity; nucleus; regulation of JAK-STAT cascade; regulation of transcription regulatory region DNA binding,PF08123;,3.00E-144,CHOYP_PABP4.2.6,,,,,,,DOT1L_HUMAN,Homo sapiens (Human),chromatin silencing [GO:0006342]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200] comp139413_c0_seq2,2714,45.7259,0.43066331,221,668,,,,,,,,,4.00E-26,CHOYP_PHC2.1.1,,,,,,,,, comp139413_c0_seq3,1181,40.2202,0.46160434,0,6,,4.00E-26,Q8IXK0,Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2),Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2),GO:0003677; GO:0035102; GO:0007275; GO:0007283; GO:0008270,DNA binding; PRC1 complex; multicellular organismal development; spermatogenesis; zinc ion binding,PF00536;,1.00E-22,CHOYP_PHC2.1.1,,,,,,,PHC2_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; protein sumoylation [GO:0016925]; spermatogenesis [GO:0007283] comp139417_c0_seq2,1267,40.4893,0.95236111,0,30,,5.00E-42,Q6P4N1,Transmembrane protein 56,Transmembrane protein 56,GO:0016021,integral to membrane,PF03798;,,,,,,,,,TMM56_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp139418_c1_seq2,218,37.156,1.48706833,4,4,,,,,,,,,,,1.00E-11,ruditapes_c8979,,,,,,, comp139419_c0_seq1,2500,39.08,0.54857605,6,35,,1.00E-177,Q5TKA1,Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein),Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein),GO:0006260; GO:0000278; GO:0005654; GO:0006351; GO:0017053,"DNA replication; mitotic cell cycle; nucleoplasm; transcription, DNA-dependent; transcriptional repressor complex",PF06584;,2.00E-112,CHOYP_LIN9.1.1,,,,,,,LIN9_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; DNA biosynthetic process [GO:0071897]; regulation of cell cycle [GO:0051726]; transcription, DNA-templated [GO:0006351]" comp139419_c0_seq2,2530,39.1304,0.55037776,18,69,,1.00E-12,Q6A332,Protein ALWAYS EARLY 3 (AtALY3),Protein ALWAYS EARLY 3 (AtALY3),GO:0003677; GO:0007049; GO:0003682; GO:0006351; GO:0017053,"DNA binding; cell cycle; chromatin binding; transcription, DNA-dependent; transcriptional repressor complex",PF06584;PF00249;,,,,,,,,,ALY3_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell cycle [GO:0007049]; transcription, DNA-templated [GO:0006351]" comp139424_c0_seq1,1431,42.2082,0.33901532,82,588,,4.00E-29,Q9SA71,Putative glycerol-3-phosphate transporter 3 (G-3-P transporter 3) (Glycerol-3-phosphate permease 3) (AtG3Pp3) (G-3-P permease 3),Putative glycerol-3-phosphate transporter 3 (G-3-P transporter 3) (Glycerol-3-phosphate permease 3) (AtG3Pp3) (G-3-P permease 3),GO:0008643; GO:0016021; GO:0055062; GO:0055085; GO:0005215,carbohydrate transport; integral to membrane; phosphate ion homeostasis; transmembrane transport; transporter activity,PF07690;,,,,,,,,,GLPT3_ARATH,Arabidopsis thaliana (Mouse-ear cress),anion transport [GO:0006820]; carbohydrate transport [GO:0008643]; phosphate ion homeostasis [GO:0055062]; transmembrane transport [GO:0055085] comp139424_c0_seq2,1147,44.0279,0.41004025,6,26,,4.00E-13,Q17QZ3,Sugar phosphate exchanger 3 (Solute carrier family 37 member 3),Sugar phosphate exchanger 3 (Solute carrier family 37 member 3),GO:0008643; GO:0016021; GO:0055085; GO:0005215,carbohydrate transport; integral to membrane; transmembrane transport; transporter activity,PF07690;,7.00E-89,CHOYP_BRAFLDRAFT_81240.1.1,,,,,,,SPX3_BOVIN,Bos taurus (Bovine),anion transport [GO:0006820]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085] comp139429_c1_seq8,408,37.7451,0.13799003,18,12,,,,,,,,,,,2.00E-12,ruditapes_c29520,,,,,,, comp139432_c0_seq1,1001,42.2577,0.66339503,213,1712,,4.00E-109,Q91642,Alpha-aspartyl dipeptidase (EC 3.4.13.21) (Asp-specific dipeptidase) (Dipeptidase E),Alpha-aspartyl dipeptidase (EC 3.4.13.21) (Asp-specific dipeptidase) (Dipeptidase E),GO:0005737; GO:0016805; GO:0006508; GO:0008236,cytoplasm; dipeptidase activity; proteolysis; serine-type peptidase activity,PF03575;,1.00E-71,CHOYP_BRAFLDRAFT_279226.1.1,,,,,,,PEPE_XENLA,Xenopus laevis (African clawed frog), comp139433_c0_seq2,1557,32.3699,0.41898301,95,583,,4.00E-91,Q9JM76,Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC),Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC),GO:0034314; GO:0005885; GO:0005737; GO:0030027,Arp2/3 complex-mediated actin nucleation; Arp2/3 protein complex; cytoplasm; lamellipodium,PF04062;,5.00E-86,CHOYP_GPN3.1.2,2.00E-125,ruditapes_c2031,,,,,ARPC3_MOUSE,Mus musculus (Mouse),Arp2/3 complex-mediated actin nucleation [GO:0034314] comp139434_c0_seq1,1849,42.2931,0.47282964,535,2603,,7.00E-177,Q499X9,"Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)","Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)",GO:0005524; GO:0004825; GO:0006431; GO:0005759; GO:0005739,ATP binding; methionine-tRNA ligase activity; methionyl-tRNA aminoacylation; mitochondrial matrix; mitochondrion,PF09334;,5.00E-36,CHOYP_SYMM.1.1,,,,,,,SYMM_MOUSE,Mus musculus (Mouse),methionyl-tRNA aminoacylation [GO:0006431] comp139439_c0_seq5,2634,33.0676,0.37661992,32,289,,2.00E-07,Q5R504,Protein FAM162A (E2-induced gene 5 protein homolog),Protein FAM162A (E2-induced gene 5 protein homolog),GO:0006919; GO:0071456; GO:0016021; GO:0005739; GO:0051402; GO:0043065; GO:0090200; GO:0006927,activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to hypoxia; integral to membrane; mitochondrion; neuron apoptotic process; positive regulation of apoptotic process; positive regulation of release of cytochrome c from mitochondria; transformed cell apoptotic process,PF06388;,,,,,,,,,F162A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to hypoxia [GO:0071456]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of release of cytochrome c from mitochondria [GO:0090200] comp139440_c0_seq1,347,37.1758,0.34370656,10,44,,2.00E-22,Q6UWZ7,BRCA1-A complex subunit Abraxas (Coiled-coil domain-containing protein 98) (Protein FAM175A),BRCA1-A complex subunit Abraxas (Coiled-coil domain-containing protein 98) (Protein FAM175A),GO:0070531; GO:0031572; GO:0016568; GO:0006302; GO:0031593; GO:0045739; GO:0010212,BRCA1-A complex; G2 DNA damage checkpoint; chromatin modification; double-strand break repair; polyubiquitin binding; positive regulation of DNA repair; response to ionizing radiation,,,,,,,,,,F175A_HUMAN,Homo sapiens (Human),chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212] comp139440_c1_seq14,1860,35.0538,0.38770845,6,25,,1.00E-06,Q8BPZ8,BRCA1-A complex subunit Abraxas (Coiled-coil domain-containing protein 98) (Protein FAM175A),BRCA1-A complex subunit Abraxas (Coiled-coil domain-containing protein 98) (Protein FAM175A),GO:0070531; GO:0031572; GO:0016568; GO:0006302; GO:0031593; GO:0045739; GO:0010212,BRCA1-A complex; G2 DNA damage checkpoint; chromatin modification; double-strand break repair; polyubiquitin binding; positive regulation of DNA repair; response to ionizing radiation,,,,,,,,,,F175A_MOUSE,Mus musculus (Mouse),chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212] comp139443_c0_seq2,979,43.7181,0.34456273,57,118,,7.00E-82,Q3B7M6,Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1),Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1),GO:0045177; GO:0051301; GO:0005814; GO:0005932; GO:0007067; GO:0000242; GO:0000922,apical part of cell; cell division; centriole; microtubule basal body; mitosis; pericentriolar material; spindle pole,PF00400;,5.00E-33,CHOYP_NEDD1.1.1,,,,,,,NEDD1_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein localization to centrosome [GO:0071539] comp139447_c1_seq1,2060,35.6311,0.50751058,72,402,,2.00E-176,Q9NQL2,Ras-related GTP-binding protein D (Rag D) (RagD),Ras-related GTP-binding protein D (Rag D) (RagD),GO:0005525; GO:0034613; GO:0071230; GO:0005764; GO:0005634; GO:0032008,GTP binding; cellular protein localization; cellular response to amino acid stimulus; lysosome; nucleus; positive regulation of TOR signaling cascade,PF04670;,9.00E-122,CHOYP_AAEL_AAEL005197.1.1,,,,,,,RRAGD_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506] comp139448_c0_seq3,2811,40.3771,0.9870193,0,0,,1.00E-06,Q9NTZ6,RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN),RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN),GO:0003723; GO:0000166; GO:0005634,RNA binding; nucleotide binding; nucleus,PF00076;,,,,,,,,,RBM12_HUMAN,Homo sapiens (Human), comp139450_c0_seq1,2618,38.9992,0.42253577,0,20,,9.00E-12,Q1AWB4,Aspartate--tRNA ligase (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS),Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS),GO:0005524; GO:0004815; GO:0006422; GO:0005737; GO:0003676,ATP binding; aspartate-tRNA ligase activity; aspartyl-tRNA aminoacylation; cytoplasm; nucleic acid binding,PF02938;PF00152;PF01336;,,,,,,,,,SYD_RUBXD,Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129),tRNA aminoacylation for protein translation [GO:0006418] comp139450_c0_seq2,2640,38.8258,0.42241829,6,75,,7.00E-58,Q043G9,Asparagine--tRNA ligase (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS),Asparagine--tRNA ligase (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS),GO:0005524; GO:0004816; GO:0006421; GO:0005737; GO:0003676,ATP binding; asparagine-tRNA ligase activity; asparaginyl-tRNA aminoacylation; cytoplasm; nucleic acid binding,PF00152;PF01336;,,,,,,,,,SYN_LACGA,Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1131 / NCIMB 11718 / AM63),asparaginyl-tRNA aminoacylation [GO:0006421] comp139450_c0_seq3,2279,40.8513,0.42144186,0,7,,0,Q2KJG3,"Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)","Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)",GO:0005524; GO:0004816; GO:0006421; GO:0005737; GO:0003676,ATP binding; asparagine-tRNA ligase activity; asparaginyl-tRNA aminoacylation; cytoplasm; nucleic acid binding,PF00152;PF01336;,0,CHOYP_ISCW_ISCW021591.1.1,4.00E-80,ruditapes2_c3018,,,,,SYNC_BOVIN,Bos taurus (Bovine),asparaginyl-tRNA aminoacylation [GO:0006421] comp139451_c0_seq1,1973,34.4653,0.48627546,34,80,,4.00E-14,Q5R4V4,SAP domain-containing ribonucleoprotein (Nuclear protein Hcc-1),SAP domain-containing ribonucleoprotein (Nuclear protein Hcc-1),GO:0003677; GO:0003723; GO:0005634; GO:0006355; GO:0006417; GO:0006351,"DNA binding; RNA binding; nucleus; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF02037;,,,,,,,,,SARNP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA export from nucleus [GO:0006406]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]" comp139452_c0_seq2,2780,37.8417,0.45244858,9,0,,,,,,,,,2.00E-68,CHOYP_E74EA.2.2,,,,,,,,, comp139452_c0_seq3,2650,37.8868,0.42086887,6,8,,1.00E-53,P11536,Ecdysone-induced protein 74EF isoform B (ETS-related protein E74B),Ecdysone-induced protein 74EF isoform B (ETS-related protein E74B),GO:0001077; GO:0006914; GO:0005634; GO:0048477; GO:0040034; GO:0035071; GO:0043565,"RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; autophagy; nucleus; oogenesis; regulation of development, heterochronic; salivary gland cell autophagic cell death; sequence-specific DNA binding",PF00178;,2.00E-68,CHOYP_E74EA.2.2,,,,,,,E74EB_DROME,Drosophila melanogaster (Fruit fly),"autophagy [GO:0006914]; cell death [GO:0008219]; oogenesis [GO:0048477]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; regulation of transcription, DNA-templated [GO:0006355]; salivary gland cell autophagic cell death [GO:0035071]" comp139457_c1_seq1,950,43.0526,0.88700055,68,498,,2.00E-06,Q60855,Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP),Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP),GO:0005524; GO:0070231; GO:0060555; GO:0060554; GO:0044257; GO:0071356; GO:0031264; GO:0097191; GO:0005739; GO:0019048; GO:0043124; GO:2001237; GO:2001243; GO:0036289; GO:0043123; GO:0046330; GO:0051092; GO:0043065; GO:2001238; GO:0032757; GO:0045651; GO:0001934; GO:0045944; GO:0051347; GO:0032760; GO:0051291; GO:0051260; GO:0004674; GO:0043235; GO:0070926; GO:2000377; GO:0097342; GO:1901026,ATP binding; T cell apoptotic process; activation of necroptosis by extracellular signals; activation of necroptosis of activated-T cells; cellular protein catabolic process; cellular response to tumor necrosis factor; death-inducing signaling complex; extrinsic apoptotic signaling pathway; mitochondrion; modulation by virus of host morphology or physiology; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of intrinsic apoptotic signaling pathway; peptidyl-serine autophosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-8 production; positive regulation of macrophage differentiation; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transferase activity; positive regulation of tumor necrosis factor production; protein heterooligomerization; protein homooligomerization; protein serine/threonine kinase activity; receptor complex; regulation of ATP:ADP antiporter activity; regulation of reactive oxygen species metabolic process; ripoptosome; ripoptosome assembly involved in necroptosis,PF00531;PF07714;PF12721;,,,1.00E-13,ruditapes_c13863,,,,,RIPK1_MOUSE,Mus musculus (Mouse),amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to tumor necrosis factor [GO:0071356]; extrinsic apoptotic signaling pathway [GO:0097191]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; peptidyl-serine autophosphorylation [GO:0036289]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of necroptotic process [GO:0060545]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of ATP:ADP antiporter activity [GO:0070926]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to tumor necrosis factor [GO:0034612]; ripoptosome assembly [GO:0097343]; ripoptosome assembly involved in necroptotic process [GO:1901026]; T cell apoptotic process [GO:0070231]; viral process [GO:0016032] comp139458_c0_seq1,1159,45.9016,0.73002986,3,963,female>male,1.00E-104,P11415,Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin),Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin),GO:0070402; GO:0003960; GO:0005829; GO:0003730; GO:0051289; GO:0005212; GO:0042178; GO:0008270,NADPH binding; NADPH:quinone reductase activity; cytosol; mRNA 3'-UTR binding; protein homotetramerization; structural constituent of eye lens; xenobiotic catabolic process; zinc ion binding,PF08240;PF00107;,,,,,,,,,QOR_CAVPO,Cavia porcellus (Guinea pig),protein homotetramerization [GO:0051289]; xenobiotic catabolic process [GO:0042178] comp139458_c0_seq2,954,43.8155,0.62781812,1,407,female>male,4.00E-14,Q71SP7,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0042470; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; melanosome; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,,,,,,,,,FAS_BOVIN,Bos taurus (Bovine),fatty acid biosynthetic process [GO:0006633] comp139459_c1_seq1,1616,39.2946,0.50468184,32,114,,9.00E-106,P42345,Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1),Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1),GO:0005524; GO:0038095; GO:0000139; GO:0016605; GO:0001030; GO:0001031; GO:0001032; GO:0031295; GO:0001156; GO:0031929; GO:0031931; GO:0031932; GO:0016049; GO:0071456; GO:0031669; GO:0008144; GO:0012505; GO:0005789; GO:0007173; GO:0008543; GO:0007281; GO:0045087; GO:0008286; GO:0005765; GO:0070438; GO:0005741; GO:0051534; GO:0010507; GO:0045792; GO:0016242; GO:0048011; GO:0018105; GO:0018107; GO:0005942; GO:0048015; GO:0030838; GO:0001938; GO:0010592; GO:0046889; GO:0010831; GO:0050731; GO:0051897; GO:0001934; GO:0051496; GO:0045945; GO:0045727; GO:0046777; GO:0030163; GO:0004674; GO:0032314; GO:0032956; GO:0043610; GO:0031998; GO:0005979; GO:0045859; GO:0032095; GO:0043200; GO:0007584; GO:0043022; GO:0031529,ATP binding; Fc-epsilon receptor signaling pathway; Golgi membrane; PML body; RNA polymerase III type 1 promoter DNA binding; RNA polymerase III type 2 promoter DNA binding; RNA polymerase III type 3 promoter DNA binding; T cell costimulation; TFIIIC-class transcription factor binding; TOR signaling cascade; TORC1 complex; TORC2 complex; cell growth; cellular response to hypoxia; cellular response to nutrient levels; drug binding; endomembrane system; endoplasmic reticulum membrane; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; germ cell development; innate immune response; insulin receptor signaling pathway; lysosomal membrane; mTOR-FKBP12-rapamycin complex; mitochondrial outer membrane; negative regulation of NFAT protein import into nucleus; negative regulation of autophagy; negative regulation of cell size; negative regulation of macroautophagy; neurotrophin TRK receptor signaling pathway; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; phosphatidylinositol 3-kinase complex; phosphatidylinositol-mediated signaling; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; positive regulation of lamellipodium assembly; positive regulation of lipid biosynthetic process; positive regulation of myotube differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of protein phosphorylation; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase III promoter; positive regulation of translation; protein autophosphorylation; protein catabolic process; protein serine/threonine kinase activity; regulation of Rac GTPase activity; regulation of actin cytoskeleton organization; regulation of carbohydrate utilization; regulation of fatty acid beta-oxidation; regulation of glycogen biosynthetic process; regulation of protein kinase activity; regulation of response to food; response to amino acid stimulus; response to nutrient; ribosome binding; ruffle organization,PF11865;PF02259;PF02260;PF00454;PF08771;,9.00E-127,CHOYP_MTOR.2.2,,,,,,,MTOR_HUMAN,Homo sapiens (Human),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; growth [GO:0040007]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of cellular response to heat [GO:1900034]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to stress [GO:0006950]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] comp139459_c1_seq2,1098,35.8834,0.54913918,12,19,,,,,,,,,3.00E-23,CHOYP_MTOR.2.2,,,,,,,,, comp139460_c0_seq1,1249,42.7542,0.42775896,153,233,,2.00E-21,Q13426,DNA repair protein XRCC4 (X-ray repair cross-complementing protein 4),DNA repair protein XRCC4 (X-ray repair cross-complementing protein 4),GO:0032807; GO:0051103; GO:0005958; GO:0033077; GO:0071285; GO:0007417; GO:0005829; GO:0006303; GO:0075713; GO:0033152; GO:0001701; GO:0045190; GO:0043524; GO:0005654; GO:0048146; GO:0051351; GO:0050769; GO:0002328; GO:0010165; GO:0010332,DNA ligase IV complex; DNA ligation involved in DNA repair; DNA-dependent protein kinase-DNA ligase 4 complex; T cell differentiation in thymus; cellular response to lithium ion; central nervous system development; cytosol; double-strand break repair via nonhomologous end joining; establishment of integrated proviral latency; immunoglobulin V(D)J recombination; in utero embryonic development; isotype switching; negative regulation of neuron apoptotic process; nucleoplasm; positive regulation of fibroblast proliferation; positive regulation of ligase activity; positive regulation of neurogenesis; pro-B cell differentiation; response to X-ray; response to gamma radiation,PF06632;,1.00E-22,CHOYP_LOC100366536.3.3,,,,,,,XRCC4_HUMAN,Homo sapiens (Human),cellular response to lithium ion [GO:0071285]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; positive regulation of ligase activity [GO:0051351]; protein sumoylation [GO:0016925]; response to X-ray [GO:0010165] comp139462_c1_seq1,2029,41.5476,0.52914923,5,29,,0,Q5ZJF6,Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10),Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF13959;PF00271;,2.00E-168,CHOYP_DDX10.1.1,,,,,,,DDX10_CHICK,Gallus gallus (Chicken),RNA secondary structure unwinding [GO:0010501] comp139462_c1_seq2,1883,41.9543,0.48660495,14,2,,0,Q80Y44,Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10),Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF13959;PF00271;,,,,,,,,,DDX10_MOUSE,Mus musculus (Mouse),RNA secondary structure unwinding [GO:0010501] comp139464_c0_seq1,1996,34.1683,0.45715253,460,1650,,,,,,,,,4.00E-31,CHOYP_LOC100366932.1.1,,,,,,,,, comp139464_c0_seq2,1516,36.3456,0.45042803,221,1002,,7.00E-75,Q568K5,N-alpha-acetyltransferase 40 (EC 2.3.1.-) (N-acetyltransferase 11) (NatD catalytic subunit),N-alpha-acetyltransferase 40 (EC 2.3.1.-) (N-acetyltransferase 11) (NatD catalytic subunit),GO:0008080,N-acetyltransferase activity,PF00583;,3.00E-31,CHOYP_LOC100366932.1.1,,,,,,,NAA40_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139465_c0_seq4,611,26.1866,0.70103281,9,23,,2.00E-16,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,2.00E-21,ruditapes_c19911,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp139466_c0_seq1,2596,36.094,0.45109672,179,268,,6.00E-135,Q9HBI1,Beta-parvin (Affixin),Beta-parvin (Affixin),GO:0030018; GO:0031532; GO:0007155; GO:0034329; GO:0005856; GO:0005829; GO:0071963; GO:0005925; GO:0030027; GO:0030032; GO:0005886,Z disc; actin cytoskeleton reorganization; cell adhesion; cell junction assembly; cytoskeleton; cytosol; establishment or maintenance of cell polarity regulating cell shape; focal adhesion; lamellipodium; lamellipodium assembly; plasma membrane,PF00307;,0,CHOYP_PARVB.1.2,,,,,,,PARVB_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; cell projection assembly [GO:0030031]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; lamellipodium assembly [GO:0030032] comp139467_c0_seq1,1506,37.3174,0.56804382,3885,19960,,1.00E-156,Q9CR47,Ribosome biogenesis protein NSA2 homolog (L-name-related protein 42) (LNR42) (TGF-beta-inducible nuclear protein 1),Ribosome biogenesis protein NSA2 homolog (L-name-related protein 42) (LNR42) (TGF-beta-inducible nuclear protein 1),GO:0005730; GO:0006364; GO:0030529,nucleolus; rRNA processing; ribonucleoprotein complex,PF01201;,1.00E-130,CHOYP_BRAFLDRAFT_60200.3.3,4.00E-154,ruditapes2_c331,,,,,NSA2_MOUSE,Mus musculus (Mouse),maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] comp139468_c1_seq1,1329,40.6321,0.98865757,0,0,,2.00E-95,Q7SYI5,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B (EC 2.4.1.122) (Core 1 O-glycan T-synthase B) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B) (Core 1 beta1,3-galactosyltransferase 1-B) (C1GalT1-B) (Core 1 beta3-Gal-T1-B)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B (EC 2.4.1.122) (Core 1 O-glycan T-synthase B) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B) (Core 1 beta1,3-galactosyltransferase 1-B) (C1GalT1-B) (Core 1 beta3-Gal-T1-B)",GO:0016266; GO:0001525; GO:0016263; GO:0016021; GO:0001822; GO:0046872,O-glycan processing; angiogenesis; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; kidney development; metal ion binding,PF02434;,2.00E-95,CHOYP_GBLP.1.7,,,,,,,C1GTB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]" comp139468_c1_seq2,1220,41.3115,1.01982576,0,0,,6.00E-90,Q7K237,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)",GO:0016267; GO:0021551; GO:0009247; GO:0016263; GO:0016021; GO:0046872,"O-glycan processing, core 1; central nervous system morphogenesis; glycolipid biosynthetic process; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; metal ion binding",PF02434;,,,,,,,,,C1GLT_DROME,Drosophila melanogaster (Fruit fly),"central nervous system morphogenesis [GO:0021551]; glycolipid biosynthetic process [GO:0009247]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; O-glycan processing, core 1 [GO:0016267]; protein glycosylation [GO:0006486]; regulation of filopodium assembly [GO:0051489]" comp139468_c1_seq3,991,42.6842,1.04791979,14,40,,3.00E-92,Q08BL3,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A (EC 2.4.1.122) (Core 1 O-glycan T-synthase A) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-A) (Core 1 beta1,3-galactosyltransferase 1-A) (C1GalT1-A) (Core 1 beta3-Gal-T1-A)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A (EC 2.4.1.122) (Core 1 O-glycan T-synthase A) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-A) (Core 1 beta1,3-galactosyltransferase 1-A) (C1GalT1-A) (Core 1 beta3-Gal-T1-A)",GO:0016266; GO:0001525; GO:0016263; GO:0016021; GO:0001822; GO:0046872,O-glycan processing; angiogenesis; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; kidney development; metal ion binding,PF02434;,2.00E-11,CHOYP_AGAP_AGAP009979.1.1,,,,,,,C1GTA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]" comp139468_c1_seq5,1563,40.627,0.96485612,0,0,,1.00E-94,Q7SYI5,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B (EC 2.4.1.122) (Core 1 O-glycan T-synthase B) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B) (Core 1 beta1,3-galactosyltransferase 1-B) (C1GalT1-B) (Core 1 beta3-Gal-T1-B)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B (EC 2.4.1.122) (Core 1 O-glycan T-synthase B) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B) (Core 1 beta1,3-galactosyltransferase 1-B) (C1GalT1-B) (Core 1 beta3-Gal-T1-B)",GO:0016266; GO:0001525; GO:0016263; GO:0016021; GO:0001822; GO:0046872,O-glycan processing; angiogenesis; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; kidney development; metal ion binding,PF02434;,8.00E-14,CHOYP_C1GLT.1.2,,,,,,,C1GTB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]" comp139470_c1_seq1,337,43.0267,0.51564146,0,35,,,,,,,,,8.00E-12,CHOYP_BRAFLDRAFT_61250.11.14,,,,,,,,, comp139470_c2_seq1,1469,37.917,0.45870627,2,13,,8.00E-39,Q9W011,Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20),Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C4D20_DROME,Drosophila melanogaster (Fruit fly), comp139470_c2_seq2,1715,37.4344,0.43655592,14,69,,2.00E-80,Q6NT55,Cytochrome P450 4F22 (EC 1.14.14.-),Cytochrome P450 4F22 (EC 1.14.14.-),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP4FN_HUMAN,Homo sapiens (Human),icosanoid metabolic process [GO:0006690] comp139471_c1_seq2,1906,41.3431,0.51621941,0,3,,7.00E-08,Q29RZ4,Zinc finger protein 2,Zinc finger protein 2,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13465;,,,,,,,,,ZNF2_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139471_c1_seq8,657,40.7915,1.13911025,0,16,,1.00E-08,Q8BIQ3,Zinc finger protein 2 (Zinc finger protein 661) (Zfp-661),Zinc finger protein 2 (Zinc finger protein 661) (Zfp-661),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF2_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139471_c1_seq9,1805,41.4958,0.55373509,0,0,,7.00E-07,Q5RJR4,Zinc finger protein 467,Zinc finger protein 467,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN467_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139471_c2_seq1,316,42.4051,0.56544602,1,12,,3.00E-06,Q8NDX6,Zinc finger protein 740 (OriLyt TD-element-binding protein 7),Zinc finger protein 740 (OriLyt TD-element-binding protein 7),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN740_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139474_c0_seq1,1193,39.6479,0.55658387,17,43,,7.00E-20,Q9D8N6,Protein lin-37 homolog (Antolefinin) (Antolefinine),Protein lin-37 homolog (Antolefinin) (Antolefinine),GO:0007049; GO:0017053,cell cycle; transcriptional repressor complex,PF15306;,,,,,,,,,LIN37_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049] comp139474_c0_seq2,1209,39.8677,0.54300398,10,126,,7.00E-20,Q9D8N6,Protein lin-37 homolog (Antolefinin) (Antolefinine),Protein lin-37 homolog (Antolefinin) (Antolefinine),GO:0007049; GO:0017053,cell cycle; transcriptional repressor complex,PF15306;,,,,,,,,,LIN37_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049] comp139475_c0_seq1,477,34.1719,0.8635991,29,103,,,,,,,,,,,7.00E-12,ruditapes_c17805,,,,,,, comp139477_c0_seq3,3284,35.81,0.8361971,283,3048,,8.00E-53,O35900,U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (snRNP core Sm-like protein Sm-x5),U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (snRNP core Sm-like protein Sm-x5),GO:0003723; GO:0008380; GO:0006397; GO:0019901; GO:0005681,RNA binding; RNA splicing; mRNA processing; protein kinase binding; spliceosomal complex,PF01423;,6.00E-70,CHOYP_LSM2.1.2,5.00E-68,ruditapes_c12183,,,,,LSM2_MOUSE,Mus musculus (Mouse),"mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp139478_c0_seq1,2106,45.4416,0.42807811,66,100,,2.00E-81,Q15811,Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),GO:0005089; GO:0097190; GO:0005509; GO:0030054; GO:0005905; GO:0005829; GO:0030139; GO:0005085; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0048011; GO:0005543; GO:0005886; GO:0043065; GO:0051897; GO:0032947; GO:0035023; GO:0051056; GO:0007264; GO:0045202; GO:0048488,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; calcium ion binding; cell junction; coated pit; cytosol; endocytic vesicle; guanyl-nucleotide exchange factor activity; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; positive regulation of apoptotic process; positive regulation of protein kinase B signaling cascade; protein complex scaffold; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; synapse; synaptic vesicle endocytosis,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,2.00E-104,CHOYP_ITSN2.1.1,,,,,,,ITSN1_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488] comp139478_c0_seq2,1546,46.5718,0.45955663,9,7,,7.00E-76,Q9WVE9,Intersectin-1 (EH domain and SH3 domain regulator of endocytosis 1),Intersectin-1 (EH domain and SH3 domain regulator of endocytosis 1),GO:0005509; GO:0030054; GO:0005905; GO:0006897; GO:0006887; GO:0030027; GO:0043005; GO:0045202,calcium ion binding; cell junction; coated pit; endocytosis; exocytosis; lamellipodium; neuron projection; synapse,PF12763;PF00018;PF07653;PF14604;,,,,,,,,,ITSN1_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; exocytosis [GO:0006887] comp139478_c0_seq3,823,42.8919,0.50814746,2,0,,5.00E-33,Q9NZM3,Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein),Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein),GO:0005089; GO:0005070; GO:0005509; GO:0005737; GO:0006897; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; SH3/SH2 adaptor activity; calcium ion binding; cytoplasm; endocytosis; phospholipid binding; regulation of Rho protein signal transduction,PF00168;PF12763;PF16652;PF00621;PF00018;PF07653;PF14604;,,,,,,,,,ITSN2_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; positive regulation of dendrite extension [GO:1903861]; regulation of Rho protein signal transduction [GO:0035023] comp139480_c0_seq1,2055,44.0876,0.41354013,123,162,,0,Q92698,DNA repair and recombination protein RAD54-like (EC 3.6.4.-) (RAD54 homolog) (hHR54) (hRAD54),DNA repair and recombination protein RAD54-like (EC 3.6.4.-) (RAD54 homolog) (hHR54) (hRAD54),GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0036310; GO:0051276; GO:0000724; GO:0004386; GO:0007126; GO:0005634; GO:0042493; GO:0010212,ATP binding; DNA binding; DNA recombination; DNA repair; annealing helicase activity; chromosome organization; double-strand break repair via homologous recombination; helicase activity; meiosis; nucleus; response to drug; response to ionizing radiation,PF00271;PF00176;,0,CHOYP_BRAFLDRAFT_281964.1.1,,,,,,,RAD54_HUMAN,Homo sapiens (Human),chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; meiotic nuclear division [GO:0007126]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212] comp139487_c1_seq1,3039,41.7901,0.56379112,0,0,,,,,,,,,0,CHOYP_UHRF1.1.1,,,,,,,,, comp139487_c1_seq2,2740,41.8613,0.54463273,0,0,,0,F6UA42,E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1),E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1),GO:0007049; GO:0000791; GO:0044729; GO:0000792; GO:0016574; GO:0010216; GO:0035064; GO:0000122; GO:0000790; GO:0051865; GO:0042787; GO:0005657; GO:0006351; GO:0004842; GO:0008270,"cell cycle; euchromatin; hemi-methylated DNA-binding; heterochromatin; histone ubiquitination; maintenance of DNA methylation; methylated histone residue binding; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein autoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; replication fork; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00628;PF02182;PF12148;PF00240;,,,,,,,,,UHRF1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell cycle [GO:0007049]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of methylation-dependent chromatin silencing [GO:0090308]; transcription, DNA-templated [GO:0006351]" comp139487_c1_seq5,2729,41.9201,0.54521632,0,0,,0,F6UA42,E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1),E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1),GO:0007049; GO:0000791; GO:0044729; GO:0000792; GO:0016574; GO:0010216; GO:0035064; GO:0000122; GO:0000790; GO:0051865; GO:0042787; GO:0005657; GO:0006351; GO:0004842; GO:0008270,"cell cycle; euchromatin; hemi-methylated DNA-binding; heterochromatin; histone ubiquitination; maintenance of DNA methylation; methylated histone residue binding; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein autoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; replication fork; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00628;PF02182;PF12148;PF00240;,0,CHOYP_UHRF1.1.1,,,,,,,UHRF1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell cycle [GO:0007049]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of methylation-dependent chromatin silencing [GO:0090308]; transcription, DNA-templated [GO:0006351]" comp139488_c0_seq1,1542,43.904,1.03881238,34,374,,9.00E-14,Q05557,Alpha-crystallin B chain (Alpha(B)-crystallin),Alpha-crystallin B chain (Alpha(B)-crystallin),GO:0030018; GO:0060561; GO:0005829; GO:0002088; GO:0046872; GO:0005739; GO:0007517; GO:0043066; GO:0043154; GO:0010629; GO:0032387; GO:0005634; GO:0005886; GO:0042803; GO:0051260; GO:0042542; GO:0001666; GO:0005212; GO:0007021,Z disc; apoptotic process involved in morphogenesis; cytosol; lens development in camera-type eye; metal ion binding; mitochondrion; muscle organ development; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of gene expression; negative regulation of intracellular transport; nucleus; plasma membrane; protein homodimerization activity; protein homooligomerization; response to hydrogen peroxide; response to hypoxia; structural constituent of eye lens; tubulin complex assembly,PF00525;PF00011;,,,,,,,,,CRYAB_ANAPL,Anas platyrhynchos (Mallard) (Anas boschas),apoptotic process involved in morphogenesis [GO:0060561]; cellular response to gamma radiation [GO:0071480]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of gene expression [GO:0010629]; negative regulation of intracellular transport [GO:0032387]; protein homooligomerization [GO:0051260]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; tubulin complex assembly [GO:0007021] comp139488_c0_seq2,881,50.1703,1.01146919,1,7,,,,,,,,,,,3.00E-33,ruditapes_c12477,,,,,,, comp139491_c1_seq2,858,40.7925,0.52349746,36,128,,3.00E-27,Q6UX04,Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8) (Antigen NY-CO-10) (Serologically defined colon cancer antigen 10),Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8) (Antigen NY-CO-10) (Serologically defined colon cancer antigen 10),GO:0071013; GO:0000398; GO:0003755; GO:0006457; GO:0000413,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization",PF00160;,2.00E-12,CHOYP_LOC100701406.1.1,,,,,,,CWC27_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]" comp139492_c0_seq1,1540,34.1558,0.55748522,507,2797,,3.00E-66,P83871,PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b),PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b),GO:0003677; GO:0005689; GO:0005686; GO:0000398; GO:0016363; GO:0016607; GO:0045893; GO:0003700; GO:0006351,"DNA binding; U12-type spliceosomal complex; U2 snRNP; mRNA splicing, via spliceosome; nuclear matrix; nuclear speck; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF03660;,2.00E-91,CHOYP_PHF5A.1.1,,,,,,,PHF5A_RAT,Rattus norvegicus (Rat),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp139501_c0_seq1,2425,35.2165,0.85212519,0,0,,6.00E-25,P18052,Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28),Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28),GO:0008286; GO:0016021; GO:0035335; GO:0006468; GO:0004725,insulin receptor signaling pathway; integral to membrane; peptidyl-tyrosine dephosphorylation; protein phosphorylation; protein tyrosine phosphatase activity,PF00102;,,,,,,,,,PTPRA_MOUSE,Mus musculus (Mouse),insulin receptor signaling pathway [GO:0008286]; protein phosphorylation [GO:0006468] comp139501_c0_seq3,2413,35.5574,0.80085073,0,272,,2.00E-29,Q15262,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0005912; GO:0030424; GO:0016477; GO:0009986; GO:0005911; GO:0034644; GO:0034614; GO:0030425; GO:0048041; GO:0005887; GO:0031256; GO:0045786; GO:0030336; GO:0010839; GO:0045892; GO:0043025; GO:0001750; GO:0034394; GO:0007179; GO:0005001,"adherens junction; axon; cell migration; cell surface; cell-cell junction; cellular response to UV; cellular response to reactive oxygen species; dendrite; focal adhesion assembly; integral to plasma membrane; leading edge membrane; negative regulation of cell cycle; negative regulation of cell migration; negative regulation of keratinocyte proliferation; negative regulation of transcription, DNA-dependent; neuronal cell body; photoreceptor outer segment; protein localization to cell surface; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein tyrosine phosphatase activity",PF00041;PF07679;PF00629;PF00102;,,,,,,,,,PTPRK_HUMAN,Homo sapiens (Human),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp139501_c0_seq5,2397,35.2524,0.833227,0,5,,8.00E-23,P23469,Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48),GO:0005737; GO:0016021; GO:0045111; GO:0046627; GO:0005634; GO:0005886; GO:0033003; GO:0005001; GO:0007185,cytoplasm; integral to membrane; intermediate filament cytoskeleton; negative regulation of insulin receptor signaling pathway; nucleus; plasma membrane; regulation of mast cell activation; transmembrane receptor protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase signaling pathway,PF00102;,,,,,,,,,PTPRE_HUMAN,Homo sapiens (Human),negative regulation of insulin receptor signaling pathway [GO:0046627]; protein dephosphorylation [GO:0006470]; regulation of mast cell activation [GO:0033003]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] comp139501_c0_seq6,1496,40.107,0.83278667,0,82,,2.00E-29,Q15262,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0005912; GO:0030424; GO:0016477; GO:0009986; GO:0005911; GO:0034644; GO:0034614; GO:0030425; GO:0048041; GO:0005887; GO:0031256; GO:0045786; GO:0030336; GO:0010839; GO:0045892; GO:0043025; GO:0001750; GO:0034394; GO:0007179; GO:0005001,"adherens junction; axon; cell migration; cell surface; cell-cell junction; cellular response to UV; cellular response to reactive oxygen species; dendrite; focal adhesion assembly; integral to plasma membrane; leading edge membrane; negative regulation of cell cycle; negative regulation of cell migration; negative regulation of keratinocyte proliferation; negative regulation of transcription, DNA-dependent; neuronal cell body; photoreceptor outer segment; protein localization to cell surface; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein tyrosine phosphatase activity",PF00041;PF07679;PF00629;PF00102;,,,,,,,,,PTPRK_HUMAN,Homo sapiens (Human),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp139504_c0_seq1,1183,43.787,0.41441471,2,0,,,,,,,,,3.00E-42,CHOYP_LOC100377362.1.1,,,,,,,,, comp139504_c0_seq2,1826,40.69,0.44575485,22,227,,7.00E-151,Q9JLH7,CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53),CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53),GO:0007420; GO:0008283; GO:0032403; GO:0000079; GO:0045664,brain development; cell proliferation; protein complex binding; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of neuron differentiation,PF05600;,,,,,,,,,CK5P3_RAT,Rattus norvegicus (Rat),apoptotic nuclear changes [GO:0030262]; brain development [GO:0007420]; cell proliferation [GO:0008283]; endoplasmic reticulum unfolded protein response [GO:0030968]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic G2 DNA damage checkpoint [GO:0007095]; negative regulation of cellular protein catabolic process [GO:1903363]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuron differentiation [GO:0045664]; regulation of phosphatase activity [GO:0010921] comp139505_c0_seq1,1522,40.6045,0.39049122,12,27,,0,Q9UKU7,"Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)","Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)",GO:0003995; GO:0009083; GO:0034641; GO:0050660; GO:0006629; GO:0005759; GO:0006355; GO:0006351; GO:0006574,"acyl-CoA dehydrogenase activity; branched-chain amino acid catabolic process; cellular nitrogen compound metabolic process; flavin adenine dinucleotide binding; lipid metabolic process; mitochondrial matrix; regulation of transcription, DNA-dependent; transcription, DNA-dependent; valine catabolic process",PF00441;PF02770;PF02771;,,,4.00E-65,ruditapes_c18494,,,,,ACAD8_HUMAN,Homo sapiens (Human),"branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; valine catabolic process [GO:0006574]" comp139505_c0_seq2,1522,40.7359,0.40467667,0,33,,0,Q9D7B6,"Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)","Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)",GO:0003995; GO:0050660; GO:0005739; GO:0006574,acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrion; valine catabolic process,PF00441;PF02770;PF02771;,0,CHOYP_ACAD8.1.1,6.00E-57,ruditapes_c23811,,,,,ACAD8_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; valine catabolic process [GO:0006574] comp139507_c0_seq1,881,44.8354,0.97914104,156,1562,,9.00E-36,P00766,Chymotrypsinogen A (EC 3.4.21.1) [Cleaved into: Chymotrypsin A chain A; Chymotrypsin A chain B; Chymotrypsin A chain C],Chymotrypsinogen A (EC 3.4.21.1) [Cleaved into: Chymotrypsin A chain A; Chymotrypsin A chain B; Chymotrypsin A chain C],GO:0007586; GO:0005615; GO:0006508; GO:0004252,digestion; extracellular space; proteolysis; serine-type endopeptidase activity,PF00089;,,,2.00E-16,ruditapes2_lrc4360,,,,,CTRA_BOVIN,Bos taurus (Bovine),digestion [GO:0007586] comp139507_c1_seq3,3437,31.0154,0.44970732,0,0,,,,,,,,,,,2.00E-11,ruditapes_c10194,,,,,,, comp139508_c0_seq2,1097,39.3801,0.42492295,103,172,,8.00E-23,Q07402,Urease accessory protein UreF,Urease accessory protein UreF,GO:0005737; GO:0016151; GO:0006807,cytoplasm; nickel cation binding; nitrogen compound metabolic process,PF01730;,,,,,,,,,UREF_BACSB,Bacillus sp. (strain TB-90),nitrogen compound metabolic process [GO:0006807] comp139509_c0_seq2,1436,40.6685,0.45896988,106,655,,2.00E-162,Q62384,Zinc finger protein ZPR1 (Zinc finger protein 259),Zinc finger protein ZPR1 (Zinc finger protein 259),GO:0005737; GO:0005730; GO:0005634; GO:0008270,cytoplasm; nucleolus; nucleus; zinc ion binding,PF03367;,4.00E-55,CHOYP_ZNF259.1.1,8.00E-30,ruditapes_c17709,,,,,ZPR1_MOUSE,Mus musculus (Mouse),apoptotic process involved in development [GO:1902742]; axon development [GO:0061564]; Cajal body organization [GO:0030576]; cellular response to epidermal growth factor stimulus [GO:0071364]; DNA endoreduplication [GO:0042023]; inner cell mass cell proliferation [GO:0001833]; microtubule cytoskeleton organization [GO:0000226]; mRNA processing [GO:0006397]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; pre-mRNA catabolic process [GO:1990261]; regulation of myelination [GO:0031641]; RNA splicing [GO:0008380]; spinal cord development [GO:0021510]; trophectodermal cell proliferation [GO:0001834] comp139510_c1_seq3,1800,37,0.35847941,7,5,,2.00E-09,Q54CH1,Arrestin domain-containing protein A,Arrestin domain-containing protein A,GO:0016021; GO:0044354; GO:0046872; GO:0045335; GO:0007165,integral to membrane; macropinosome; metal ion binding; phagocytic vesicle; signal transduction,PF02752;PF00339;PF01363;,,,,,,,,,ADCA_DICDI,Dictyostelium discoideum (Slime mold),hyperosmotic response [GO:0006972]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165] comp139512_c0_seq12,1724,41.2993,0.65340931,0,0,,7.00E-68,Q801R4,CTD small phosphatase-like protein 2-A (CTDSP-like 2-A) (EC 3.1.3.-),CTD small phosphatase-like protein 2-A (CTDSP-like 2-A) (EC 3.1.3.-),GO:0016311; GO:0004721,dephosphorylation; phosphoprotein phosphatase activity,PF03031;,1.00E-81,CHOYP_CCNB.2.2,,,,,,,CTL2A_XENLA,Xenopus laevis (African clawed frog), comp139512_c0_seq7,1712,41.1799,0.6617628,0,0,,6.00E-68,Q801R4,CTD small phosphatase-like protein 2-A (CTDSP-like 2-A) (EC 3.1.3.-),CTD small phosphatase-like protein 2-A (CTDSP-like 2-A) (EC 3.1.3.-),GO:0016311; GO:0004721,dephosphorylation; phosphoprotein phosphatase activity,PF03031;,1.00E-81,CHOYP_CCNB.2.2,,,,,,,CTL2A_XENLA,Xenopus laevis (African clawed frog), comp139519_c0_seq1,2076,36.3198,0.61532941,1074,25570,,1.00E-32,Q9CPU4,Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III),Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III),GO:0005783; GO:0005789; GO:0004602; GO:0004364; GO:0016021; GO:0005635,endoplasmic reticulum; endoplasmic reticulum membrane; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; nuclear envelope,PF01124;,2.00E-15,CHOYP_NEMVEDRAFT_V1G240887.1.2,2.00E-53,ruditapes_c8766,,,,,MGST3_MOUSE,Mus musculus (Mouse),response to organonitrogen compound [GO:0010243] comp139520_c1_seq1,1131,39.0805,0.89959708,33,307,,2.00E-14,A1STS0,"Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) (Ap4A hydrolase) (Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase) (Diadenosine tetraphosphatase)","Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) (Ap4A hydrolase) (Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase) (Diadenosine tetraphosphatase)",GO:0008803,bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity,PF00149;,,,,,,,,,APAH_PSYIN,Psychromonas ingrahamii (strain 37), comp139521_c0_seq2,1520,44.2105,0.51377849,42,115,,4.00E-127,Q9JLI3,"Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]","Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]",GO:0005794; GO:0005783; GO:0005615; GO:0016021; GO:0004222; GO:0006508; GO:0008270,Golgi apparatus; endoplasmic reticulum; extracellular space; integral to membrane; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01431;PF05649;,2.00E-34,CHOYP_NEP.1.2,2.00E-56,ruditapes2_c2012,,,,,MMEL1_MOUSE,Mus musculus (Mouse), comp139522_c2_seq2,1044,37.1648,0.41653418,7,103,,,,,,,,,,,9.00E-47,ruditapes_c13536,,,,,,, comp139524_c2_seq1,696,45.2586,0.36571758,97,252,,8.00E-30,Q969T9,WW domain-binding protein 2 (WBP-2),WW domain-binding protein 2 (WBP-2),,,PF02893;PF10349;,1.00E-57,CHOYP_LOC589108.2.2,,,,,,,WBP2_HUMAN,Homo sapiens (Human),"cellular response to estrogen stimulus [GO:0071391]; establishment of protein localization [GO:0045184]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]" comp139530_c0_seq1,1120,35.4464,0.25609219,0,7,,8.00E-55,A6QP05,Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,DHR12_BOVIN,Bos taurus (Bovine), comp139530_c0_seq10,2046,38.7097,0.4481665,0,0,,1.00E-143,Q5JPH6,"Probable glutamate--tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)","Probable glutamate--tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)",GO:0005524; GO:0004818; GO:0050561; GO:0006424; GO:0005759; GO:0005739; GO:0070127; GO:0000049,ATP binding; glutamate-tRNA ligase activity; glutamate-tRNA(Gln) ligase activity; glutamyl-tRNA aminoacylation; mitochondrial matrix; mitochondrion; tRNA aminoacylation for mitochondrial protein translation; tRNA binding,PF00749;,,,,,,,,,SYEM_HUMAN,Homo sapiens (Human),glutamyl-tRNA aminoacylation [GO:0006424]; tRNA aminoacylation for mitochondrial protein translation [GO:0070127] comp139530_c0_seq3,3336,38.5791,0.39581945,0,0,,1.00E-13,Q39617,"Protochlorophyllide reductase, chloroplastic (PCR) (EC 1.3.1.33) (NADPH-protochlorophyllide oxidoreductase) (POR)","Protochlorophyllide reductase, chloroplastic (PCR) (EC 1.3.1.33) (NADPH-protochlorophyllide oxidoreductase) (POR)",GO:0015995; GO:0009507; GO:0015979; GO:0016630,chlorophyll biosynthetic process; chloroplast; photosynthesis; protochlorophyllide reductase activity,PF00106;,2.00E-76,CHOYP_BRAFLDRAFT_114204.1.1,,,,,,,POR_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),chlorophyll biosynthetic process [GO:0015995]; photosynthesis [GO:0015979] comp139530_c0_seq4,2308,39.8614,0.43847539,0,0,,2.00E-142,Q5JPH6,"Probable glutamate--tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)","Probable glutamate--tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)",GO:0005524; GO:0004818; GO:0050561; GO:0006424; GO:0005759; GO:0005739; GO:0070127; GO:0000049,ATP binding; glutamate-tRNA ligase activity; glutamate-tRNA(Gln) ligase activity; glutamyl-tRNA aminoacylation; mitochondrial matrix; mitochondrion; tRNA aminoacylation for mitochondrial protein translation; tRNA binding,PF00749;,2.00E-35,CHOYP_DMOJ_GI16866.1.1,,,,,,,SYEM_HUMAN,Homo sapiens (Human),glutamyl-tRNA aminoacylation [GO:0006424]; tRNA aminoacylation for mitochondrial protein translation [GO:0070127] comp139530_c0_seq5,1494,36.747,0.33810945,0,0,,1.00E-129,A6QP05,Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1),GO:0016491,oxidoreductase activity,PF00106;,8.00E-77,CHOYP_BRAFLDRAFT_114204.1.1,,,,,,,DHR12_BOVIN,Bos taurus (Bovine), comp139530_c0_seq9,1549,36.7334,0.38352113,0,0,,2.00E-12,Q9M2E2,(+)-neomenthol dehydrogenase (EC 1.1.1.208) (Menthone:neomenthol reductase) (Short-chain dehydrogenase/reductase 1) (AtSDR1),(+)-neomenthol dehydrogenase (EC 1.1.1.208) (Menthone:neomenthol reductase) (Short-chain dehydrogenase/reductase 1) (AtSDR1),GO:0047501; GO:0006952,(+)-neomenthol dehydrogenase activity; defense response,PF00106;,,,,,,,,,SDR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),defense response [GO:0006952] comp139531_c1_seq1,1817,42.6527,0.4904766,363,3912,,0,P81178,"Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1)","Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1)",GO:0004029; GO:0006068; GO:0005759,aldehyde dehydrogenase (NAD) activity; ethanol catabolic process; mitochondrial matrix,PF00171;,2.00E-149,CHOYP_ALDH2.3.3,7.00E-57,ruditapes_c266,,,,,ALDH2_MESAU,Mesocricetus auratus (Golden hamster),ethanol catabolic process [GO:0006068] comp139532_c2_seq1,3817,40.8436,0.74896317,30,729,,8.00E-96,Q6KEQ9,Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X),Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X),GO:0005509; GO:0007156; GO:0016021; GO:0010923; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; negative regulation of phosphatase activity; plasma membrane,PF00028;PF08266;PF08374;,,,,,,,,,PC11X_PIG,Sus scrofa (Pig),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of phosphatase activity [GO:0010923] comp139532_c2_seq2,2333,41.9631,0.76954489,0,7,,3.00E-30,Q9Y5I4,Protocadherin alpha-C2 (PCDH-alpha-C2),Protocadherin alpha-C2 (PCDH-alpha-C2),GO:0005509; GO:0007155; GO:0007156; GO:0005887; GO:0007399,calcium ion binding; cell adhesion; homophilic cell adhesion; integral to plasma membrane; nervous system development,PF00028;PF08266;PF16492;PF15974;,2.00E-11,CHOYP_PC11X.1.2,,,,,,,PCDC2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] comp139533_c0_seq1,998,43.5872,0.51230821,0,0,,3.00E-08,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139533_c0_seq3,1191,40.2183,0.39609668,0,0,,2.00E-07,Q8BZW4,Zinc finger protein 120 (Zinc finger protein 31) (mZF31),Zinc finger protein 120 (Zinc finger protein 31) (mZF31),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN120_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139533_c0_seq5,1683,43.1373,0.46227064,0,0,,2.00E-07,Q8CIV7,Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO),Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO),GO:0003677; GO:0001525; GO:0009953; GO:0048557; GO:0060214; GO:0001947; GO:0060347; GO:0060716; GO:0046872; GO:0045746; GO:0008285; GO:0045617; GO:0010944; GO:0045892; GO:0001755; GO:0001842; GO:0005634; GO:0045893; GO:0051726; GO:0010837; GO:0000981; GO:0044212,"DNA binding; angiogenesis; dorsal/ventral pattern formation; embryonic digestive tract morphogenesis; endocardium formation; heart looping; heart trabecula formation; labyrinthine layer blood vessel development; metal ion binding; negative regulation of Notch signaling pathway; negative regulation of cell proliferation; negative regulation of keratinocyte differentiation; negative regulation of transcription by competitive promoter binding; negative regulation of transcription, DNA-dependent; neural crest cell migration; neural fold formation; nucleus; positive regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of keratinocyte proliferation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription regulatory region DNA binding",,,,,,,,,,OVOL2_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; dorsal/ventral pattern formation [GO:0009953]; embryonic digestive tract morphogenesis [GO:0048557]; endocardium formation [GO:0060214]; epidermal cell differentiation [GO:0009913]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of keratinocyte proliferation [GO:0010837]" comp139533_c0_seq6,1429,38.8383,0.46491388,0,0,,4.00E-08,Q92010,Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 5) (ZF5),Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 5) (ZF5),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZF161_CHICK,Gallus gallus (Chicken),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp139533_c0_seq7,653,46.4012,0.54509691,0,8,,8.00E-06,B7ZRU9,MDS1 and EVI1 complex locus protein EVI1-A (Ecotropic virus integration site 1 protein homolog-A) (Evi-1) (xEvi-1),MDS1 and EVI1 complex locus protein EVI1-A (Ecotropic virus integration site 1 protein homolog-A) (Evi-1) (xEvi-1),GO:0003677; GO:0046872; GO:0000122; GO:0016607; GO:0039013; GO:0039022; GO:0072196; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nuclear speck; pronephric distal tubule morphogenesis; pronephric duct development; proximal/distal pattern formation involved in pronephric nephron development; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,EVI1A_XENLA,Xenopus laevis (African clawed frog),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; pronephros development [GO:0048793]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; transcription, DNA-templated [GO:0006351]" comp139534_c0_seq1,407,36.3636,0.29852019,11,11,,2.00E-09,Q4UKQ3,Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C),Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C),GO:0003723; GO:0009982; GO:0001522; GO:0006364,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; rRNA processing,PF00849;PF01479;,,,,,,,,,RLUC_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364] comp139534_c1_seq1,1747,38.5804,0.3087113,0,0,,1.00E-10,Q676U5,Autophagy-related protein 16-1 (APG16-like 1),Autophagy-related protein 16-1 (APG16-like 1),GO:0005776; GO:0000045; GO:0000421; GO:0034045; GO:0051260; GO:0015031,autophagic vacuole; autophagic vacuole assembly; autophagic vacuole membrane; pre-autophagosomal structure membrane; protein homooligomerization; protein transport,PF08614;PF00400;,,,,,,,,,A16L1_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031] comp139534_c1_seq2,2104,36.8346,0.32485883,16,20,,2.00E-07,Q8N0X2,Sperm-associated antigen 16 protein (Pf20 protein homolog),Sperm-associated antigen 16 protein (Pf20 protein homolog),GO:0042384; GO:0035085; GO:0005874; GO:0005634; GO:0007283,cilium assembly; cilium axoneme; microtubule; nucleus; spermatogenesis,PF00400;,,,,,,,,,SPG16_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; cell motility in response to calcium ion [GO:0097231]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; microtubule sliding [GO:0051012]; sperm axoneme assembly [GO:0007288] comp139534_c1_seq3,1574,39.5807,0.32604659,2,0,,6.00E-66,E9Q349,WD repeat-containing protein 25,WD repeat-containing protein 25,,,PF00400;,,,,,,,,,WDR25_MOUSE,Mus musculus (Mouse), comp139534_c2_seq1,525,39.8095,0.33998277,18,8,,3.00E-37,Q6DBR0,RNA pseudouridylate synthase domain-containing protein 4,RNA pseudouridylate synthase domain-containing protein 4,GO:0003723; GO:0009982; GO:0001522,RNA binding; pseudouridine synthase activity; pseudouridine synthesis,PF00849;,,,,,,,,,RUSD4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),tRNA pseudouridine synthesis [GO:0031119] comp139538_c0_seq1,1345,34.7212,0.78668973,251,5889,,2.00E-34,O96081,Calmodulin-B (CaM B),Calmodulin-B (CaM B),GO:0005509,calcium ion binding,PF13499;,8.00E-13,CHOYP_CALM.16.50,2.00E-93,ruditapes_c670,,,,,CALMB_HALRO,Halocynthia roretzi (Sea squirt) (Cynthia roretzi), comp139540_c0_seq1,1934,40.0207,0.43994782,0,0,,1.00E-78,Q810V0,U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10),U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10),GO:0005694; GO:0010923; GO:0005730; GO:0006364; GO:0030529,chromosome; negative regulation of phosphatase activity; nucleolus; rRNA processing; ribonucleoprotein complex,PF04006;,5.00E-74,CHOYP_LOC101169524.1.1,1.00E-29,ruditapes_c7823,,,,,MPP10_MOUSE,Mus musculus (Mouse),maturation of SSU-rRNA [GO:0030490]; negative regulation of phosphatase activity [GO:0010923] comp139540_c0_seq2,2009,39.771,0.47965648,0,0,,,,,,,,,5.00E-74,CHOYP_LOC101169524.1.1,,,,,,,,, comp139542_c0_seq1,2744,40.1239,0.39977498,0,0,,0,Q174R2,Histone-arginine methyltransferase CARMER (EC 2.1.1.-) (EC 2.1.1.125),Histone-arginine methyltransferase CARMER (EC 2.1.1.319),GO:0006338; GO:0005737; GO:0034969; GO:0042054; GO:0008469; GO:0005634; GO:0035242; GO:0035241; GO:0006355; GO:0006351,"chromatin remodeling; cytoplasm; histone arginine methylation; histone methyltransferase activity; histone-arginine N-methyltransferase activity; nucleus; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05185;,0,CHOYP_LOC100743901.1.1,,,,,,,CARM1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139542_c0_seq2,2619,39.5571,0.38255484,0,0,,0,B3M1E1,Histone-arginine methyltransferase CARMER (EC 2.1.1.-) (EC 2.1.1.125),Histone-arginine methyltransferase CARMER (EC 2.1.1.319),GO:0006338; GO:0005737; GO:0034969; GO:0042054; GO:0008469; GO:0005634; GO:0035242; GO:0035241; GO:0006355; GO:0006351,"chromatin remodeling; cytoplasm; histone arginine methylation; histone methyltransferase activity; histone-arginine N-methyltransferase activity; nucleus; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05185;,0,CHOYP_LOC100743901.1.1,,,,,,,CARM1_DROAN,Drosophila ananassae (Fruit fly),"chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139542_c0_seq4,1684,39.4893,0.4119209,0,0,,5.00E-32,Q174R2,Histone-arginine methyltransferase CARMER (EC 2.1.1.-) (EC 2.1.1.125),Histone-arginine methyltransferase CARMER (EC 2.1.1.319),GO:0006338; GO:0005737; GO:0034969; GO:0042054; GO:0008469; GO:0005634; GO:0035242; GO:0035241; GO:0006355; GO:0006351,"chromatin remodeling; cytoplasm; histone arginine methylation; histone methyltransferase activity; histone-arginine N-methyltransferase activity; nucleus; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05185;,,,,,,,,,CARM1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139544_c0_seq2,1564,44.757,0.67138595,0,0,,5.00E-141,P51116,Fragile X mental retardation syndrome-related protein 2,Fragile X mental retardation syndrome-related protein 2,GO:0003723; GO:0022625,RNA binding; cytosolic large ribosomal subunit,PF05641;PF12235;PF16096;PF00013;,,,,,,,,,FXR2_HUMAN,Homo sapiens (Human),negative regulation of translation [GO:0017148]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp139544_c0_seq3,1582,44.8167,0.66337431,0,0,,3.00E-140,P51116,Fragile X mental retardation syndrome-related protein 2,Fragile X mental retardation syndrome-related protein 2,GO:0003723; GO:0022625,RNA binding; cytosolic large ribosomal subunit,PF05641;PF12235;PF16096;PF00013;,,,,,,,,,FXR2_HUMAN,Homo sapiens (Human),negative regulation of translation [GO:0017148]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp139544_c0_seq5,1412,45.1841,0.63122658,0,0,,,,,,,,,3.00E-43,CHOYP_FMRP.2.2,,,,,,,,, comp139545_c0_seq1,1246,38.5233,0.41743187,69,190,,6.00E-41,Q3ZBK2,Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM),Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM),GO:0016209; GO:0005737; GO:0055114; GO:0045670,antioxidant activity; cytoplasm; oxidation-reduction process; regulation of osteoclast differentiation,PF13911;,,,,,,,,,F213A_BOVIN,Bos taurus (Bovine),oxidation-reduction process [GO:0055114]; regulation of osteoclast differentiation [GO:0045670] comp139545_c0_seq2,1258,38.5533,0.4550292,59,211,,5.00E-41,Q6AXX6,Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Sperm head protein 1),Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Sperm head protein 1),GO:0016209; GO:0005737; GO:0055114; GO:0045670,antioxidant activity; cytoplasm; oxidation-reduction process; regulation of osteoclast differentiation,PF13911;,6.00E-20,CHOYP_F213A.1.1,1.00E-33,ruditapes2_c2083,,,,,F213A_RAT,Rattus norvegicus (Rat),oxidation-reduction process [GO:0055114]; regulation of osteoclast differentiation [GO:0045670] comp139548_c1_seq1,305,47.8689,0.34511649,12,14,,2.00E-24,Q3UVL4,Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog),Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog),GO:0000938; GO:0006914; GO:0006869; GO:0015031; GO:0042147,"GARP complex; autophagy; lipid transport; protein transport; retrograde transport, endosome to Golgi",,,,,,,,,,VPS51_MOUSE,Mus musculus (Mouse),"autophagy [GO:0006914]; endocytic recycling [GO:0032456]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp139548_c3_seq8,810,44.6914,0.55067985,31,74,,4.00E-106,Q155U0,Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free),Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free),GO:0005794; GO:0007030; GO:0048193; GO:0044241; GO:0006869; GO:0015031; GO:0010517,Golgi apparatus; Golgi organization; Golgi vesicle transport; lipid digestion; lipid transport; protein transport; regulation of phospholipase activity,,7.00E-131,CHOYP_VPS51.1.1,9.00E-33,ruditapes_c15791,,,,,VPS51_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; lipid digestion [GO:0044241]; lipid transport [GO:0006869]; protein transport [GO:0015031]; regulation of phospholipase activity [GO:0010517] comp139549_c1_seq2,1995,31.0777,0.31175817,114,162,,,,,,,,,,,6.00E-14,ruditapes_c1219,,,,,,, comp139549_c1_seq4,1191,39.4626,0.5937902,2,77,,,,,,,,,4.00E-35,CHOYP_BRAFLDRAFT_284971.1.1,,,,,,,,, comp139549_c1_seq5,1202,39.4343,0.61082643,26,203,,2.00E-79,P13984,General transcription factor IIF subunit 2 (EC 3.6.4.12) (ATP-dependent helicase GTF2F2) (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30),General transcription factor IIF subunit 2 (EC 3.6.4.12) (ATP-dependent helicase GTF2F2) (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30),GO:0006370; GO:0005524; GO:0008026; GO:0003677; GO:0000398; GO:0015630; GO:0005654; GO:0050434; GO:0006355; GO:0006368; GO:0005674; GO:0006367; GO:0016032,"7-methylguanosine mRNA capping; ATP binding; ATP-dependent helicase activity; DNA binding; mRNA splicing, via spliceosome; microtubule cytoskeleton; nucleoplasm; positive regulation of viral transcription; regulation of transcription, DNA-dependent; transcription elongation from RNA polymerase II promoter; transcription factor TFIIF complex; transcription initiation from RNA polymerase II promoter; viral process",PF02270;,,,,,,,,,T2FB_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp139552_c0_seq2,230,25.6522,0.79840219,1,15,,,,,,,,,,,4.00E-17,ruditapes_c13109,,,,,,, comp139556_c0_seq2,2478,34.4229,0.37986522,0,7,,7.00E-24,Q9SKX5,Probable polyamine oxidase 2 (AtPAO2) (EC 1.5.3.-) (Amine oxidase 1),Probable polyamine oxidase 2 (AtPAO2) (EC 1.5.3.-) (Amine oxidase 1),GO:0005777; GO:0006598; GO:0046592,peroxisome; polyamine catabolic process; polyamine oxidase activity,PF01593;,,,,,,,,,PAO2_ARATH,Arabidopsis thaliana (Mouse-ear cress),polyamine catabolic process [GO:0006598] comp139556_c0_seq3,2449,34.7489,0.40484337,4,13,,1.00E-20,Q9LID0,Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2),Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2),GO:0003677; GO:0051568; GO:0016491; GO:0006355; GO:0006351,"DNA binding; histone H3-K4 methylation; oxidoreductase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01593;PF04433;,,,,,,,,,LDL2_ARATH,Arabidopsis thaliana (Mouse-ear cress),"histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139556_c0_seq4,2463,34.5108,0.40867269,0,0,,6.00E-14,Q8NB78,Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2),Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2),GO:0003677; GO:0043046; GO:0050660; GO:0034648; GO:0034649; GO:0007275; GO:0005634; GO:0016491; GO:0044030; GO:0006349; GO:0006355; GO:0006351; GO:0008270,"DNA binding; DNA methylation involved in gamete generation; flavin adenine dinucleotide binding; histone demethylase activity (H3-dimethyl-K4 specific); histone demethylase activity (H3-monomethyl-K4 specific); multicellular organismal development; nucleus; oxidoreductase activity; regulation of DNA methylation; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01593;PF04433;PF07496;,,,,,,,,,KDM1B_HUMAN,Homo sapiens (Human),"DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; multicellular organism development [GO:0007275]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139556_c0_seq5,2435,34.7433,0.40763059,0,0,,8.00E-24,Q9SKX5,Probable polyamine oxidase 2 (AtPAO2) (EC 1.5.3.-) (Amine oxidase 1),Probable polyamine oxidase 2 (AtPAO2) (EC 1.5.3.-) (Amine oxidase 1),GO:0005777; GO:0006598; GO:0046592,peroxisome; polyamine catabolic process; polyamine oxidase activity,PF01593;,,,,,,,,,PAO2_ARATH,Arabidopsis thaliana (Mouse-ear cress),polyamine catabolic process [GO:0006598] comp139557_c0_seq1,2042,39.618,0.49972494,0,674,,4.00E-07,O15303,Metabotropic glutamate receptor 6 (mGluR6),Metabotropic glutamate receptor 6 (mGluR6),GO:0007216; GO:0004930; GO:0000139; GO:0001640; GO:0030425; GO:0050908; GO:0005789; GO:0008066; GO:0005887; GO:0007626; GO:0035841; GO:0090280; GO:0060041; GO:0007268,G-protein coupled glutamate receptor signaling pathway; G-protein coupled receptor activity; Golgi membrane; adenylate cyclase inhibiting G-protein coupled glutamate receptor activity; dendrite; detection of light stimulus involved in visual perception; endoplasmic reticulum membrane; glutamate receptor activity; integral to plasma membrane; locomotory behavior; new growing cell tip; positive regulation of calcium ion import; retina development in camera-type eye; synaptic transmission,PF00003;PF01094;PF07562;,8.00E-34,CHOYP_BTKL.1.1,,,,,,,GRM6_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; detection of visible light [GO:0009584]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; locomotory behavior [GO:0007626]; positive regulation of calcium ion import [GO:0090280]; regulation of synaptic transmission, glutamatergic [GO:0051966]; retina development in camera-type eye [GO:0060041]" comp139559_c1_seq1,3543,45.8369,0.45150951,169,311,,7.00E-109,Q9VT28,Protein furry,Protein furry,GO:0048800; GO:0045177; GO:0005938; GO:0008407; GO:0070593; GO:0035317; GO:0048601; GO:0045860; GO:0045893; GO:0048814; GO:0042052; GO:0006351,"antennal morphogenesis; apical part of cell; cell cortex; chaeta morphogenesis; dendrite self-avoidance; imaginal disc-derived wing hair organization; oocyte morphogenesis; positive regulation of protein kinase activity; positive regulation of transcription, DNA-dependent; regulation of dendrite morphogenesis; rhabdomere development; transcription, DNA-dependent",PF14225;PF14228;PF14222;,3.00E-124,CHOYP_LOC657755.1.1,,,,,,,FRY_DROME,Drosophila melanogaster (Fruit fly),"actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]" comp139560_c0_seq1,1270,43.4646,0.60066988,31,99,,3.00E-160,Q567W6,Diphthamide biosynthesis protein 1 (DPH1 homolog),Diphthamide biosynthesis protein 1 (DPH1 homolog),GO:0005737; GO:0005634; GO:0017183,cytoplasm; nucleus; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01866;,,,,,,,,,DPH1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp139560_c0_seq2,1578,41.0646,0.58933722,73,475,,0,A7SLX5,Diphthamide biosynthesis protein 1,Diphthamide biosynthesis protein 1,GO:0005737; GO:0017183,cytoplasm; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01866;,1.00E-130,CHOYP_LOC100378925.1.1,7.00E-69,ruditapes_c20546,,,,,DPH1_NEMVE,Nematostella vectensis (Starlet sea anemone),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp139560_c0_seq3,601,43.4276,0.42434328,0,10,,6.00E-19,A4QN59,Diphthamide biosynthesis protein 2 (DPH2 homolog),Diphthamide biosynthesis protein 2 (DPH2 homolog),GO:0005737; GO:0017183,cytoplasm; peptidyl-diphthamide biosynthetic process from peptidyl-histidine,PF01866;,,,,,,,,,DPH2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] comp139561_c0_seq1,1558,39.2811,0.51881892,3,21,,9.00E-31,Q8N8Q8,Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18),Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18),GO:0031305; GO:0051204; GO:0008565; GO:0008535,integral to mitochondrial inner membrane; protein insertion into mitochondrial membrane; protein transporter activity; respiratory chain complex IV assembly,PF02096;,,,,,,,,,COX18_HUMAN,Homo sapiens (Human),protein insertion into mitochondrial membrane [GO:0051204]; respiratory chain complex IV assembly [GO:0008535] comp139561_c0_seq2,1670,38.7425,0.4978378,23,84,,2.00E-30,Q8N8Q8,Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18),Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18),GO:0031305; GO:0051204; GO:0008565; GO:0008535,integral to mitochondrial inner membrane; protein insertion into mitochondrial membrane; protein transporter activity; respiratory chain complex IV assembly,PF02096;,,,,,,,,,COX18_HUMAN,Homo sapiens (Human),protein insertion into mitochondrial membrane [GO:0051204]; respiratory chain complex IV assembly [GO:0008535] comp139562_c2_seq1,773,42.5614,0.28634898,0,0,,,,,,,,,2.00E-124,CHOYP_KRP95.1.1,,,,,,,,, comp139562_c2_seq2,2403,42.6966,0.32022196,0,0,,3.00E-50,Q8J1G7,Kinesin-like protein CIN8,Kinesin-like protein CIN8,GO:0005524; GO:0000235; GO:0051301; GO:0000778; GO:0005871; GO:0005828; GO:0007019; GO:0007018; GO:0008569; GO:0000070; GO:0008574; GO:0000073,ATP binding; astral microtubule; cell division; condensed nuclear chromosome kinetochore; kinesin complex; kinetochore microtubule; microtubule depolymerization; microtubule-based movement; minus-end-directed microtubule motor activity; mitotic sister chromatid segregation; plus-end-directed microtubule motor activity; spindle pole body separation,PF00225;,4.00E-58,CHOYP_LOC100377381.1.2,,,,,,,CIN8_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),cell division [GO:0051301]; chromosome segregation [GO:0007059]; metabolic process [GO:0008152]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019]; mitotic spindle assembly [GO:0090307]; mitotic spindle elongation [GO:0000022]; spindle pole body separation [GO:0000073] comp139562_c2_seq3,2799,42.2651,0.34673905,0,0,,0,O15066,"Kinesin-like protein KIF3B (HH0048) (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed]","Kinesin-like protein KIF3B (HH0048) (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed]",GO:0005524; GO:0008089; GO:0019886; GO:0007596; GO:0005813; GO:0005829; GO:0007368; GO:0016939; GO:0007100; GO:0005873; GO:0008574; GO:0072383; GO:0090307; GO:0005876,ATP binding; anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; centrosome; cytosol; determination of left/right symmetry; kinesin II complex; mitotic centrosome separation; plus-end kinesin complex; plus-end-directed microtubule motor activity; plus-end-directed vesicle transport along microtubule; spindle assembly involved in mitosis; spindle microtubule,PF00225;,0,CHOYP_KRP95.1.1,,,,,,,KIF3B_HUMAN,Homo sapiens (Human),"anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; determination of left/right symmetry [GO:0007368]; microtubule-based movement [GO:0007018]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp139562_c2_seq4,1169,41.574,0.35908567,0,0,,0,P46871,Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit),Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,3.00E-11,CHOYP_LOC100372958.1.1,,,,,,,KRP95_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018] comp139563_c0_seq2,1528,31.2827,0.48488393,125,902,,,,,,,,,,,1.00E-15,ruditapes_c1831,,,,,,, comp139563_c0_seq3,1753,31.2607,0.5399453,93,222,,,,,,,,,,,3.00E-11,ruditapes_c3458,,,,,,, comp139566_c0_seq1,284,21.831,0.30159104,40,0,,,,,,,,,,,1.00E-11,ruditapes_c17805,,,,,,, comp139567_c0_seq1,4382,39.6623,0.44777097,3,15,,0,P51892,DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006310; GO:0006260; GO:0007049; GO:0051301; GO:0046872; GO:0005634,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; DNA recombination; DNA replication; cell cycle; cell division; metal ion binding; nucleus,PF04679;PF01068;PF04675;,,,,,,,,,DNLI1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260] comp139567_c0_seq2,4370,39.6568,0.448973,2,10,,0,P18858,DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0009653; GO:0006284; GO:0051301; GO:0005694; GO:0000724; GO:0006303; GO:0006273; GO:0046872; GO:0005739; GO:0000278; GO:0005654; GO:0006297; GO:0042542; GO:0000722; GO:0032201; GO:0006283,"ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; anatomical structure morphogenesis; base-excision repair; cell division; chromosome; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end joining; lagging strand elongation; metal ion binding; mitochondrion; mitotic cell cycle; nucleoplasm; nucleotide-excision repair, DNA gap filling; response to hydrogen peroxide; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair",PF04679;PF01068;PF04675;,0,CHOYP_DNLI1.1.2,,,,,,,DNLI1_HUMAN,Homo sapiens (Human),"anatomical structure morphogenesis [GO:0009653]; base-excision repair [GO:0006284]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp139567_c0_seq3,4212,39.981,0.43410429,0,0,,7.00E-87,A4WH24,DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP]),DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP]),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006310; GO:0006260; GO:0007049; GO:0051301; GO:0046872,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; DNA recombination; DNA replication; cell cycle; cell division; metal ion binding,PF04679;PF01068;PF04675;,,,,,,,,,DNLI_PYRAR,Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321),cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260] comp139567_c0_seq4,3134,41.5763,0.39080221,0,0,,0,P51892,DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006310; GO:0006260; GO:0007049; GO:0051301; GO:0046872; GO:0005634,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; DNA recombination; DNA replication; cell cycle; cell division; metal ion binding; nucleus,PF04679;PF01068;PF04675;,0,CHOYP_DNLI1.1.2,,,,,,,DNLI1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260] comp139567_c0_seq6,3122,41.4798,0.37874382,39,26,,0,P51892,DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006310; GO:0006260; GO:0007049; GO:0051301; GO:0046872; GO:0005634,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; DNA recombination; DNA replication; cell cycle; cell division; metal ion binding; nucleus,PF04679;PF01068;PF04675;,8.00E-11,CHOYP_BRAFLDRAFT_69217.1.1,,,4.00E-155,AM868574.p.cg.6,7,,DNLI1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260] comp139568_c4_seq3,1258,39.9841,0.40443328,118,640,,5.00E-105,P54278,Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2),Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2),GO:0005524; GO:0016887; GO:0032389; GO:0004519; GO:0006298; GO:0090305; GO:0007131; GO:0042493; GO:0032138; GO:0016446; GO:0016447,ATP binding; ATPase activity; MutLalpha complex; endonuclease activity; mismatch repair; nucleic acid phosphodiester bond hydrolysis; reciprocal meiotic recombination; response to drug; single base insertion or deletion binding; somatic hypermutation of immunoglobulin genes; somatic recombination of immunoglobulin gene segments,PF01119;PF08676;,9.00E-107,CHOYP_PMS2.1.1,,,8.00E-107,AM857512.p.cg.6,7,,PMS2_HUMAN,Homo sapiens (Human),mismatch repair [GO:0006298]; response to drug [GO:0042493]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp139575_c0_seq2,1407,40.6539,0.46682654,44,166,,3.00E-80,Q8JFW4,Probable inactive tRNA-specific adenosine deaminase-like protein 3 (tRNA-specific adenosine-34 deaminase subunit adat3),Probable inactive tRNA-specific adenosine deaminase-like protein 3 (tRNA-specific adenosine-34 deaminase subunit adat3),GO:0016787; GO:0008033; GO:0008270,hydrolase activity; tRNA processing; zinc ion binding,PF00383;,,,,,,,,,ADAT3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),RNA modification [GO:0009451]; tRNA processing [GO:0008033] comp139577_c0_seq1,1488,45.3629,0.7248888,0,0,,0,Q9NWZ5,Uridine-cytidine kinase-like 1 (EC 2.7.1.48),Uridine-cytidine kinase-like 1 (EC 2.7.1.48),GO:0005524; GO:0044211; GO:0044206; GO:0005783; GO:0019048; GO:0005634; GO:0016773; GO:0004849,"ATP binding; CTP salvage; UMP salvage; endoplasmic reticulum; modulation by virus of host morphology or physiology; nucleus; phosphotransferase activity, alcohol group as acceptor; uridine kinase activity",PF00485;PF14681;,,,,,,,,,UCKL1_HUMAN,Homo sapiens (Human),CTP salvage [GO:0044211]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; viral process [GO:0016032] comp139577_c0_seq4,1001,40.3596,0.74194817,0,0,,2.00E-20,Q9RU32,Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase),Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase),GO:0005525; GO:0044206; GO:0000287; GO:0004845; GO:0006223,GTP binding; UMP salvage; magnesium ion binding; uracil phosphoribosyltransferase activity; uracil salvage,PF14681;,,,,,,,,,UPP_DEIRA,Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422),pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223] comp139577_c0_seq6,1354,44.9778,0.69292156,0,0,,3.00E-74,Q9QYG8,Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Uridine monophosphokinase 2),Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Uridine monophosphokinase 2),GO:0005524; GO:0044211; GO:0044206; GO:0071453; GO:0005829; GO:0007631; GO:0043231; GO:0016773; GO:0016579; GO:0048678; GO:0004849,"ATP binding; CTP salvage; UMP salvage; cellular response to oxygen levels; cytosol; feeding behavior; intracellular membrane-bounded organelle; phosphotransferase activity, alcohol group as acceptor; protein deubiquitination; response to axon injury; uridine kinase activity",PF00485;,0,CHOYP_AAEL_AAEL011273.1.1,,,,,,,UCK2_RAT,Rattus norvegicus (Rat),cellular response to oxygen levels [GO:0071453]; CMP salvage [GO:0006238]; CTP salvage [GO:0044211]; feeding behavior [GO:0007631]; protein deubiquitination [GO:0016579]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; response to axon injury [GO:0048678]; UMP salvage [GO:0044206] comp139577_c0_seq8,1763,43.1083,0.68810755,0,0,,5.00E-122,Q9LK34,"Uridine kinase-like protein 2, chloroplastic [Includes: Uridine kinase (UK) (EC 2.7.1.48); Putative uracil phosphoribosyltransferase (UPRTase) (EC 2.4.2.9) (UMP pyrophosphorylase)]","Uridine kinase-like protein 2, chloroplastic [Includes: Uridine kinase (UK) (EC 2.7.1.48); Putative uracil phosphoribosyltransferase (UPRTase) (EC 2.4.2.9) (UMP pyrophosphorylase)]",GO:0006207; GO:0005524; GO:0044211; GO:0005525; GO:0044206; GO:0009507; GO:0005829; GO:0016773; GO:2001006; GO:1901141; GO:2000904; GO:0016757; GO:0004849,"'de novo' pyrimidine nucleobase biosynthetic process; ATP binding; CTP salvage; GTP binding; UMP salvage; chloroplast; cytosol; phosphotransferase activity, alcohol group as acceptor; regulation of cellulose biosynthetic process; regulation of lignin biosynthetic process; regulation of starch metabolic process; transferase activity, transferring glycosyl groups; uridine kinase activity",PF00485;PF14681;,,,,,,,,,UKL2_ARATH,Arabidopsis thaliana (Mouse-ear cress),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CTP salvage [GO:0044211]; regulation of cellulose biosynthetic process [GO:2001006]; regulation of lignin biosynthetic process [GO:1901141]; regulation of starch metabolic process [GO:2000904]; UMP salvage [GO:0044206] comp139577_c0_seq9,1897,43.5424,0.71619283,0,0,,0,Q9NWZ5,Uridine-cytidine kinase-like 1 (EC 2.7.1.48),Uridine-cytidine kinase-like 1 (EC 2.7.1.48),GO:0005524; GO:0044211; GO:0044206; GO:0005783; GO:0019048; GO:0005634; GO:0016773; GO:0004849,"ATP binding; CTP salvage; UMP salvage; endoplasmic reticulum; modulation by virus of host morphology or physiology; nucleus; phosphotransferase activity, alcohol group as acceptor; uridine kinase activity",PF00485;PF14681;,0,CHOYP_AAEL_AAEL011273.1.1,,,,,,,UCKL1_HUMAN,Homo sapiens (Human),CTP salvage [GO:0044211]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; viral process [GO:0016032] comp139578_c0_seq1,2532,40.9953,1.06642714,4259,36,male>female,6.00E-95,Q8BWA5,Kelch-like protein 31 (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL),Kelch-like protein 31 (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL),GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07707;PF00651;PF01344;,,,,,,,,,KLH31_MOUSE,Mus musculus (Mouse),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp139579_c0_seq1,2011,42.7151,0.44481302,109,531,,5.00E-160,Q8N6R0,Methyltransferase-like protein 13 (EC 2.1.1.-),Methyltransferase-like protein 13 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF08241;,,,,,,,,,MET13_HUMAN,Homo sapiens (Human), comp139579_c0_seq2,269,41.2639,0.35133862,6,19,,,,,,,,,9.00E-29,CHOYP_BRAFLDRAFT_204501.1.1,,,,,,,,, comp139581_c0_seq1,884,39.1403,0.33606091,0,0,,9.00E-08,O75467,Zinc finger protein 324A (Zinc finger protein ZF5128),Zinc finger protein 324A (Zinc finger protein ZF5128),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,Z324A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139582_c0_seq1,1499,34.3562,0.37113801,1241,4797,,8.00E-29,Q7T2P6,Mitochondrial import inner membrane translocase subunit Tim23,Mitochondrial import inner membrane translocase subunit Tim23,GO:0015450; GO:0016021; GO:0005744; GO:0042719; GO:0007275; GO:0045039,P-P-bond-hydrolysis-driven protein transmembrane transporter activity; integral to membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial intermembrane space protein transporter complex; multicellular organismal development; protein import into mitochondrial inner membrane,PF02466;,,,,,,,,,TIM23_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),intracellular protein transport [GO:0006886]; multicellular organism development [GO:0007275]; protein import into mitochondrial inner membrane [GO:0045039]; protein import into mitochondrial matrix [GO:0030150] comp139583_c0_seq1,1038,41.5222,0.5818477,3,30,,5.00E-82,Q7T2D4,Endoplasmic reticulum-Golgi intermediate compartment protein 2,Endoplasmic reticulum-Golgi intermediate compartment protein 2,GO:0005794; GO:0005789; GO:0033116; GO:0016021; GO:0016192,Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; vesicle-mediated transport,PF07970;,1.00E-53,CHOYP_ERGI2.2.2,,,,,,,ERGI2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),vesicle-mediated transport [GO:0016192] comp139583_c0_seq3,863,39.9768,0.69714994,3,0,,,,,,,,,6.00E-12,CHOYP_ERGI2.1.2,,,,,,,,, comp139586_c1_seq2,1989,37.9085,0.43898424,22,221,,0,P55039,Developmentally-regulated GTP-binding protein 2 (DRG-2),Developmentally-regulated GTP-binding protein 2 (DRG-2),GO:0005525; GO:0005737; GO:0005739; GO:0007165,GTP binding; cytoplasm; mitochondrion; signal transduction,PF01926;PF16897;PF02824;,0,CHOYP_DRG2.1.1,,,,,,,DRG2_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp139586_c1_seq4,1012,39.9209,0.51280803,0,0,,0,P55039,Developmentally-regulated GTP-binding protein 2 (DRG-2),Developmentally-regulated GTP-binding protein 2 (DRG-2),GO:0005525; GO:0005737; GO:0005739; GO:0007165,GTP binding; cytoplasm; mitochondrion; signal transduction,PF01926;PF16897;PF02824;,0,CHOYP_DRG2.1.1,,,,,,,DRG2_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp139590_c0_seq1,1105,36.2896,0.43115582,125,607,,2.00E-24,Q8WW12,PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein),PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein),GO:0007049; GO:0005634; GO:0043161; GO:0016567,cell cycle; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination,PF15473;,7.00E-25,CHOYP_PCNP.1.1,,,,,,,PCNP_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] comp139592_c0_seq1,979,39.428,0.95742182,118,665,,1.00E-12,Q1T769,Protein MIS12 homolog,Protein MIS12 homolog,GO:0000444; GO:0051301; GO:0007059; GO:0051382; GO:0007067; GO:0005634,MIS12/MIND type complex; cell division; chromosome segregation; kinetochore assembly; mitosis; nucleus,PF05859;,,,,,,,,,MIS12_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to kinetochore [GO:0034501] comp139593_c0_seq1,1734,41.6955,0.76209924,195,3303,,0,P79896,Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284),Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284),GO:0051903; GO:0004022; GO:0005737; GO:0006069; GO:0008270,S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD) activity; cytoplasm; ethanol oxidation; zinc ion binding,PF08240;PF00107;,2.00E-136,CHOYP_ADHX.1.1,1.00E-41,ruditapes_c10583,,,,,ADHX_SPAAU,Sparus aurata (Gilthead sea bream),ethanol oxidation [GO:0006069] comp139594_c0_seq1,2601,39.3695,0.43795504,28,647,,4.00E-172,P69341,Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease),Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease),GO:0003723; GO:0005737; GO:0046872; GO:0000184; GO:0090305; GO:0000166; GO:0005634; GO:0004535,"RNA binding; cytoplasm; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleic acid phosphodiester bond hydrolysis; nucleotide binding; nucleus; poly(A)-specific ribonuclease activity",PF04857;PF01424;PF08675;,2.00E-29,CHOYP_PARN.1.1,,,,,,,PARN_BOVIN,Bos taurus (Bovine),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp139594_c0_seq2,2510,39.2829,0.45574703,40,230,,3.00E-172,P69341,Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease),Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease),GO:0003723; GO:0005737; GO:0046872; GO:0000184; GO:0090305; GO:0000166; GO:0005634; GO:0004535,"RNA binding; cytoplasm; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleic acid phosphodiester bond hydrolysis; nucleotide binding; nucleus; poly(A)-specific ribonuclease activity",PF04857;PF01424;PF08675;,,,,,,,,,PARN_BOVIN,Bos taurus (Bovine),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp139594_c0_seq3,865,41.2717,0.46432914,0,0,,1.00E-07,Q5RAR6,Target of EGR1 protein 1,Target of EGR1 protein 1,GO:0046872; GO:0016607; GO:0003676; GO:0005730,metal ion binding; nuclear speck; nucleic acid binding; nucleolus,PF04857;PF00642;,7.00E-30,CHOYP_PARN.1.1,,,,,,,TOE1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp139596_c0_seq1,2403,34.2905,0.54673987,52,517,,6.00E-21,P10073,Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50),Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSC22_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp139600_c0_seq1,2103,39.6576,0.46268529,8876,4725,,6.00E-93,Q9H3K2,Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5),Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5),GO:0006915; GO:0016021; GO:0005743,apoptotic process; integral to membrane; mitochondrial inner membrane,,2.00E-60,CHOYP_LOC100693508.1.1,6.00E-21,ruditapes_c28866,,,,,GHITM_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915] comp139602_c0_seq1,1664,39.9639,1.21251887,0,7,,9.00E-96,Q9UBQ7,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0034641; GO:0007588; GO:0008465; GO:0046487; GO:0030267; GO:0016618; GO:0005782; GO:0042803; GO:0051259,NAD binding; NADPH binding; cellular nitrogen compound metabolic process; excretion; glycerate dehydrogenase activity; glyoxylate metabolic process; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; peroxisomal matrix; protein homodimerization activity; protein oligomerization,PF00389;PF02826;,3.00E-12,CHOYP_GRHPR.1.1,6.00E-51,ruditapes_c25099,,,,,GRHPR_HUMAN,Homo sapiens (Human),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp139602_c0_seq2,1828,39.4967,1.17243625,10,129,,3.00E-92,Q91Z53,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0005737; GO:0007588; GO:0008465; GO:0030267; GO:0016618; GO:0051259,NAD binding; NADPH binding; cytoplasm; excretion; glycerate dehydrogenase activity; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; protein oligomerization,PF00389;PF02826;,,,,,,,,,GRHPR_MOUSE,Mus musculus (Mouse),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp139602_c0_seq3,1817,39.2955,1.17801046,29,167,,5.00E-26,P0C1E9,Uncharacterized protein in proB 3'region (EC 1.-.-.-),Uncharacterized protein in proB 3'region (EC 1.-.-.-),GO:0048037; GO:0016616,"cofactor binding; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF02826;,4.00E-12,CHOYP_GRHPR.1.1,,,,,,,YPRB2_CORML,Corynebacterium melassecola, comp139607_c3_seq1,586,46.7577,0.91798153,0,85,,6.00E-51,P08478,Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)],Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)],GO:0005507; GO:0016021; GO:0006518; GO:0004598; GO:0004504; GO:0030658,copper ion binding; integral to membrane; peptide metabolic process; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; transport vesicle membrane,PF03712;PF01082;PF01436;,2.00E-34,CHOYP_AMDA.1.1,,,,,,,AMDA_XENLA,Xenopus laevis (African clawed frog),peptide metabolic process [GO:0006518] comp139608_c1_seq1,1470,41.3605,0.30540029,195,1005,,7.00E-52,Q5BK46,Ribonuclease H1 (RNase H1) (EC 3.1.26.4),Ribonuclease H1 (RNase H1) (EC 3.1.26.4),GO:0005737; GO:0000287; GO:0003676; GO:0090305; GO:0004523,cytoplasm; magnesium ion binding; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity,PF01693;PF00075;,,,,,,,,,RNH1_RAT,Rattus norvegicus (Rat),"DNA replication, removal of RNA primer [GO:0043137]" comp139609_c0_seq1,2137,40.2433,0.55869332,3192,25983,,7.00E-37,Q99541,Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP),Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP),GO:0044255; GO:0005783; GO:0005576; GO:0005811; GO:0019915; GO:0015909; GO:0005634; GO:0005886; GO:0042493; GO:0014070; GO:0044281,cellular lipid metabolic process; endoplasmic reticulum; extracellular region; lipid particle; lipid storage; long-chain fatty acid transport; nucleus; plasma membrane; response to drug; response to organic cyclic compound; small molecule metabolic process,PF03036;,,,8.00E-32,ruditapes_c1773,,,,,PLIN2_HUMAN,Homo sapiens (Human),lipid storage [GO:0019915]; long-chain fatty acid transport [GO:0015909]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070] comp139614_c2_seq1,1537,34.2876,0.68757781,4953,27486,,1.00E-26,Q5RB31,Protein transport protein Sec61 subunit beta,Protein transport protein Sec61 subunit beta,GO:0030433; GO:0031205; GO:0016021; GO:0000060; GO:0030970,"ER-associated protein catabolic process; endoplasmic reticulum Sec complex; integral to membrane; protein import into nucleus, translocation; retrograde protein transport, ER to cytosol",PF03911;,3.00E-50,CHOYP_LOC663663.3.3,2.00E-88,ruditapes_c5901,,,,,SC61B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein import into nucleus, translocation [GO:0000060]; retrograde protein transport, ER to cytosol [GO:0030970]" comp139626_c0_seq1,3061,45.4427,0.44301074,1791,6705,,0,Q7KZF4,Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator),Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator),GO:0016442; GO:0005737; GO:0031047; GO:0042470; GO:0005739; GO:0019048; GO:0004518; GO:0003676; GO:0090305; GO:0005634; GO:0006355; GO:0003712; GO:0006351,"RISC complex; cytoplasm; gene silencing by RNA; melanosome; mitochondrion; modulation by virus of host morphology or physiology; nuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleus; regulation of transcription, DNA-dependent; transcription cofactor activity; transcription, DNA-dependent",PF00565;PF00567;,0,CHOYP_LOC594315.1.1,,,,,,,SND1_HUMAN,Homo sapiens (Human),"gene silencing by RNA [GO:0031047]; osteoblast differentiation [GO:0001649]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp139631_c0_seq1,2151,39.1911,0.52595214,234,885,,6.00E-161,Q9NVX2,Notchless protein homolog 1,Notchless protein homolog 1,GO:0007219; GO:0001826; GO:0005730,Notch signaling pathway; inner cell mass cell differentiation; nucleolus,PF08154;PF00400;,0,CHOYP_LOC585438.1.1,,,,,,,NLE1_HUMAN,Homo sapiens (Human),hematopoietic stem cell homeostasis [GO:0061484]; inner cell mass cell differentiation [GO:0001826]; kidney development [GO:0001822]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of mitotic cell cycle [GO:0045930]; Notch signaling pathway [GO:0007219]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; ribosomal large subunit biogenesis [GO:0042273]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756] comp139632_c0_seq1,2042,39.667,1.29919745,0,0,,8.00E-98,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp139632_c0_seq2,1304,39.4172,1.36680408,0,79,,5.00E-42,Q24451,"Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0005795; GO:0030246; GO:0035010; GO:0005783; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006517; GO:0006486; GO:0008270,"Golgi membrane; Golgi stack; carbohydrate binding; encapsulation of foreign target; endoplasmic reticulum; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein deglycosylation; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MAN2_DROME,Drosophila melanogaster (Fruit fly),encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein N-linked glycosylation [GO:0006487]; rhodopsin biosynthetic process [GO:0016063] comp139632_c0_seq8,1686,41.3405,1.28478051,0,0,,8.00E-33,Q8VHC8,Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B),Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B),GO:0004559; GO:0030246; GO:0005764; GO:0006013; GO:0008270,alpha-mannosidase activity; carbohydrate binding; lysosome; mannose metabolic process; zinc ion binding,PF09261;PF01074;PF07748;,,,,,,,,,MA2B1_CAVPO,Cavia porcellus (Guinea pig),mannose metabolic process [GO:0006013] comp139634_c1_seq2,4201,35.6582,0.4569085,0,0,,,,,,,,,5.00E-135,CHOYP_BRAFLDRAFT_84005.1.1,,,,,,,,, comp139634_c1_seq4,4386,35.4081,0.45141837,23,76,,5.00E-168,Q8VCM8,Nicalin (Nicastrin-like protein),Nicalin (Nicastrin-like protein),GO:0005789; GO:0016021; GO:0005634; GO:0008233; GO:0006508; GO:0009966,endoplasmic reticulum membrane; integral to membrane; nucleus; peptidase activity; proteolysis; regulation of signal transduction,PF04389;,,,,,,,,,NCLN_MOUSE,Mus musculus (Mouse),protein destabilization [GO:0031648]; regulation of protein complex assembly [GO:0043254]; regulation of signal transduction [GO:0009966] comp139634_c1_seq6,4306,35.1602,0.49605271,0,63,,3.00E-168,Q8VCM8,Nicalin (Nicastrin-like protein),Nicalin (Nicastrin-like protein),GO:0005789; GO:0016021; GO:0005634; GO:0008233; GO:0006508; GO:0009966,endoplasmic reticulum membrane; integral to membrane; nucleus; peptidase activity; proteolysis; regulation of signal transduction,PF04389;,5.00E-135,CHOYP_BRAFLDRAFT_84005.1.1,,,,,,,NCLN_MOUSE,Mus musculus (Mouse),protein destabilization [GO:0031648]; regulation of protein complex assembly [GO:0043254]; regulation of signal transduction [GO:0009966] comp139635_c0_seq1,4090,41.198,0.44583827,0,0,,,,,,,,,5.00E-116,CHOYP_LOC100642881.1.1,,,,,,,,, comp139635_c0_seq14,2837,43.8139,0.50025263,0,0,,0,Q8NCN5,"Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)","Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)",GO:0004047; GO:0006546; GO:0005759; GO:0016491; GO:0006090; GO:0010510,aminomethyltransferase activity; glycine catabolic process; mitochondrial matrix; oxidoreductase activity; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate,PF01266;PF16350;PF01571;PF08669;,,,,,,,,,PDPR_HUMAN,Homo sapiens (Human),regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510] comp139635_c0_seq15,3566,40.5216,0.45953578,0,0,,0,Q8NCN5,"Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)","Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)",GO:0004047; GO:0006546; GO:0005759; GO:0016491; GO:0006090; GO:0010510,aminomethyltransferase activity; glycine catabolic process; mitochondrial matrix; oxidoreductase activity; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate,PF01266;PF16350;PF01571;PF08669;,4.00E-116,CHOYP_LOC100642881.1.1,,,,,,,PDPR_HUMAN,Homo sapiens (Human),regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510] comp139635_c0_seq18,1375,41.0182,0.55844185,0,0,,6.00E-27,Q1INT8,Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein),Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein),GO:0004047; GO:0005737; GO:0006546; GO:0008483,aminomethyltransferase activity; cytoplasm; glycine catabolic process; transaminase activity,PF01571;PF08669;,,,,,,,,,GCST_KORVE,Koribacter versatilis (strain Ellin345),glycine decarboxylation via glycine cleavage system [GO:0019464] comp139635_c0_seq2,3817,41.2628,0.45217177,0,0,,0,Q8NCN5,"Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)","Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)",GO:0004047; GO:0006546; GO:0005759; GO:0016491; GO:0006090; GO:0010510,aminomethyltransferase activity; glycine catabolic process; mitochondrial matrix; oxidoreductase activity; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate,PF01266;PF16350;PF01571;PF08669;,,,,,,,,,PDPR_HUMAN,Homo sapiens (Human),regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510] comp139635_c0_seq4,2210,37.3303,0.48780018,0,0,,5.00E-26,Q1INT8,Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein),Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein),GO:0004047; GO:0005737; GO:0006546; GO:0008483,aminomethyltransferase activity; cytoplasm; glycine catabolic process; transaminase activity,PF01571;PF08669;,,,,,,,,,GCST_KORVE,Koribacter versatilis (strain Ellin345),glycine decarboxylation via glycine cleavage system [GO:0019464] comp139635_c0_seq5,3672,40.9586,0.47623733,0,0,,,,,,,,,4.00E-116,CHOYP_LOC100642881.1.1,,,,,,,,, comp139635_c0_seq6,2731,43.3541,0.48348658,0,0,,0,Q8NCN5,"Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)","Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)",GO:0004047; GO:0006546; GO:0005759; GO:0016491; GO:0006090; GO:0010510,aminomethyltransferase activity; glycine catabolic process; mitochondrial matrix; oxidoreductase activity; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate,PF01266;PF16350;PF01571;PF08669;,3.00E-116,CHOYP_LOC100642881.1.1,,,,,,,PDPR_HUMAN,Homo sapiens (Human),regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510] comp139635_c0_seq8,1881,35.9915,0.46913462,0,0,,6.00E-13,Q8CFA2,"Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)","Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)",GO:0004047; GO:0006546; GO:0005739; GO:0008483,aminomethyltransferase activity; glycine catabolic process; mitochondrion; transaminase activity,PF01571;PF08669;,,,,,,,,,GCST_MOUSE,Mus musculus (Mouse),glycine decarboxylation via glycine cleavage system [GO:0019464] comp139638_c3_seq3,2345,39.2324,0.81716823,0,12,,3.00E-10,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp139638_c3_seq4,2289,39.3185,0.79889973,0,0,,3.00E-10,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp139639_c0_seq2,1018,40.8644,0.42934016,0,0,,2.00E-33,Q9WUJ8,Origin recognition complex subunit 6,Origin recognition complex subunit 6,GO:0003677; GO:0006261; GO:0005664,DNA binding; DNA-dependent DNA replication; nuclear origin of replication recognition complex,PF05460;,,,,,,,,,ORC6_MOUSE,Mus musculus (Mouse),DNA-dependent DNA replication [GO:0006261] comp139639_c0_seq6,882,41.4966,0.41861621,0,0,,2.00E-43,Q2HJF3,Origin recognition complex subunit 6,Origin recognition complex subunit 6,GO:0003677; GO:0006260; GO:0005664,DNA binding; DNA replication; nuclear origin of replication recognition complex,PF05460;,,,,,,,,,ORC6_BOVIN,Bos taurus (Bovine),DNA replication [GO:0006260] comp139641_c0_seq1,4626,44.1634,0.6072167,968,5190,,8.00E-22,Q7RXA6,Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Rotamase),Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (EC 6.3.2.-) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Rotamase),GO:0005634; GO:0003755; GO:0006457; GO:0000413; GO:0000151; GO:0004842,nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; ubiquitin ligase complex; ubiquitin-protein ligase activity,PF00160;PF04564;,,,,,,,,,PPIL2_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),protein folding [GO:0006457] comp139641_c0_seq2,742,43.3962,0.55920086,0,0,,1.00E-66,P0C1I9,Peptidyl-prolyl cis-trans isomerase cyp11 (PPIase cyp11) (EC 5.2.1.8) (Cyclophilin cyp11) (Rotamase cyp11),Peptidyl-prolyl cis-trans isomerase cyp11 (PPIase cyp11) (EC 5.2.1.8) (Cyclophilin cyp11) (Rotamase cyp11),GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,2.00E-54,CHOYP_PPIG.1.1,3.00E-89,ruditapes2_c356,,,,,CYP11_RHIO9,Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar),protein folding [GO:0006457] comp139642_c0_seq1,3262,49.4175,0.60318698,332,94,,6.00E-45,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,6.00E-108,CHOYP_LOC575058.1.1,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp139642_c0_seq3,489,46.6258,0.4155441,0,0,,6.00E-08,Q9I7U4,Titin (D-Titin) (Kettin),Titin (D-Titin) (Kettin),GO:0030018; GO:0003779; GO:0051301; GO:0000794; GO:0040011; GO:0007498; GO:0005875; GO:0007076; GO:0016203; GO:0007520; GO:0035206; GO:0045214; GO:0007062; GO:0007519; GO:0007525; GO:0008307; GO:0007522,Z disc; actin binding; cell division; condensed nuclear chromosome; locomotion; mesoderm development; microtubule associated complex; mitotic chromosome condensation; muscle attachment; myoblast fusion; regulation of hemocyte proliferation; sarcomere organization; sister chromatid cohesion; skeletal muscle tissue development; somatic muscle development; structural constituent of muscle; visceral muscle development,PF06582;PF00041;PF07679;PF00018;,,,,,,,,,TITIN_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522] comp139642_c0_seq4,322,50.9317,0.53228978,5,11,,8.00E-06,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp139644_c0_seq1,2185,38.3524,0.41163741,129,400,,1.00E-64,Q96I25,Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17),Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17),GO:0003723; GO:0008380; GO:0006397; GO:0000166; GO:0005634; GO:0005681,RNA binding; RNA splicing; mRNA processing; nucleotide binding; nucleus; spliceosomal complex,PF01585;PF00076;,,,,,,,,,SPF45_HUMAN,Homo sapiens (Human),"alternative mRNA splicing, via spliceosome [GO:0000380]" comp139644_c0_seq2,2060,39.1748,0.40371939,85,320,,3.00E-44,P42698,"DNA-damage-repair/toleration protein DRT111, chloroplastic","DNA-damage-repair/toleration protein DRT111, chloroplastic (REQUIRED FOR SNC4-1D protein 2)",GO:0006281; GO:0003723; GO:0009507; GO:0000166; GO:0005634,DNA repair; RNA binding; chloroplast; nucleotide binding; nucleus,PF01585;,2.00E-79,CHOYP_SPF45.1.1,,,,,,,DR111_ARATH,Arabidopsis thaliana (Mouse-ear cress),DNA repair [GO:0006281]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] comp139647_c1_seq2,2027,35.2245,0.34354035,38,214,,3.00E-23,Q4V8A0,E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog),E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog),GO:0016605; GO:0019789; GO:0030915; GO:0051301; GO:0090398; GO:0000781; GO:0000724; GO:0007067; GO:0034184; GO:0045842; GO:0016925; GO:0000722; GO:0008270,"PML body; SUMO ligase activity; Smc5-Smc6 complex; cell division; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; mitosis; positive regulation of maintenance of mitotic sister chromatid cohesion; positive regulation of mitotic metaphase/anaphase transition; protein sumoylation; telomere maintenance via recombination; zinc ion binding",PF11789;,3.00E-14,CHOYP_BRAFLDRAFT_117049.1.1,,,,,,,NSE2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; telomere maintenance via recombination [GO:0000722] comp139647_c1_seq3,1602,32.397,0.28965529,111,431,,2.00E-14,Q96MF7,E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (hMMS21) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog),E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (hMMS21) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog),GO:0016605; GO:0019789; GO:0030915; GO:0051301; GO:0090398; GO:0000781; GO:0000724; GO:0007067; GO:0034184; GO:0045842; GO:0016925; GO:0000722; GO:0008270,"PML body; SUMO ligase activity; Smc5-Smc6 complex; cell division; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; mitosis; positive regulation of maintenance of mitotic sister chromatid cohesion; positive regulation of mitotic metaphase/anaphase transition; protein sumoylation; telomere maintenance via recombination; zinc ion binding",PF11789;,2.00E-14,CHOYP_BRAFLDRAFT_117049.1.1,,,,,,,NSE2_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein sumoylation [GO:0016925]; telomere maintenance via recombination [GO:0000722] comp139648_c0_seq2,736,42.1196,0.38809972,49,186,,2.00E-103,Q9ULR0,Pre-mRNA-splicing factor ISY1 homolog,Pre-mRNA-splicing factor ISY1 homolog,GO:0071013; GO:0000398,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome",PF06246;,1.00E-107,CHOYP_ISY1.1.1,,,,,,,ISY1_HUMAN,Homo sapiens (Human),"generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp139654_c0_seq1,3319,42.1211,1.16297946,6248,27,male>female,2.00E-35,Q25390,Alpha-scruin,Alpha-scruin,,,PF01344;,,,,,,,,,SCRA_LIMPO,Limulus polyphemus (Atlantic horseshoe crab), comp139655_c1_seq1,1308,33.3333,1.37905685,103,499,,7.00E-06,Q6NSZ9,Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498),Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;,,,,,,,,,ZN498_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp139656_c1_seq1,2380,44.3277,0.5223633,169,251,,2.00E-172,Q80X82,Symplekin,Symplekin,GO:0007155; GO:0005737; GO:0005856; GO:0006378; GO:0005654; GO:0005886; GO:0035307; GO:0005923,cell adhesion; cytoplasm; cytoskeleton; mRNA polyadenylation; nucleoplasm; plasma membrane; positive regulation of protein dephosphorylation; tight junction,PF11935;PF12295;,2.00E-119,CHOYP_SYMPK.1.1,,,,,,,SYMPK_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; mRNA polyadenylation [GO:0006378]; positive regulation of protein dephosphorylation [GO:0035307] comp139656_c1_seq3,1190,43.1092,0.4349364,74,76,,,,,,,,,2.00E-19,CHOYP_SYMPK.1.1,,,,,,,,, comp139657_c0_seq2,839,38.379,0.45412483,0,8,,2.00E-26,Q5U4I3,Cyclin-D1-binding protein 1 homolog,Cyclin-D1-binding protein 1 homolog,GO:0007049; GO:0005737; GO:0005634,cell cycle; cytoplasm; nucleus,,,,,,,,,,CCDB1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726] comp139657_c0_seq5,1356,38.4218,0.32069024,18,109,,6.00E-62,Q5U4I3,Cyclin-D1-binding protein 1 homolog,Cyclin-D1-binding protein 1 homolog,GO:0007049; GO:0005737; GO:0005634,cell cycle; cytoplasm; nucleus,,,,,,,,,,CCDB1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726] comp139659_c0_seq1,3656,38.512,0.35309383,5894,27633,,0,P23787,Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (p97) (Valosin-containing protein) (VCP),Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (p97) (Valosin-containing protein) (VCP),GO:0005524; GO:0016887; GO:0030433; GO:0000785; GO:0005737; GO:0005829; GO:0006302; GO:0008289; GO:0005634; GO:0018279; GO:0034214; GO:0016567; GO:0035861; GO:0019985; GO:0006810,ATP binding; ATPase activity; ER-associated protein catabolic process; chromatin; cytoplasm; cytosol; double-strand break repair; lipid binding; nucleus; protein N-linked glycosylation via asparagine; protein hexamerization; protein ubiquitination; site of double-strand break; translesion synthesis; transport,PF00004;PF02933;PF02359;PF09336;,0,CHOYP_TERA.1.1,7.00E-29,ruditapes2_c2523,,,,,TERA_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein hexamerization [GO:0034214]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; translesion synthesis [GO:0019985]; transport [GO:0006810] comp139660_c0_seq1,5022,43.0307,0.64210255,3078,43621,,0,P11024,"NAD(P) transhydrogenase, mitochondrial (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)","NAD(P) transhydrogenase, mitochondrial (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)",GO:0008750; GO:0050661; GO:0016021; GO:0005743; GO:0015992; GO:0072593,NAD(P)+ transhydrogenase (AB-specific) activity; NADP binding; integral to membrane; mitochondrial inner membrane; proton transport; reactive oxygen species metabolic process,PF01262;PF05222;PF02233;PF12769;,0,CHOYP_LOC100633041.1.1,7.00E-94,ruditapes_c901,,,,,NNTM_BOVIN,Bos taurus (Bovine),cell redox homeostasis [GO:0045454]; NADPH regeneration [GO:0006740]; proton transport [GO:0015992]; reactive oxygen species metabolic process [GO:0072593] comp139664_c0_seq1,365,39.4521,0.1413138,12,52,,4.00E-11,Q54VE0,AP-4 complex subunit epsilon (AP-4 adapter complex subunit epsilon) (Adapter-related protein complex 4 subunit epsilon) (Epsilon subunit of AP-4) (Epsilon-adaptin),AP-4 complex subunit epsilon (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon) (Epsilon subunit of AP-4) (Epsilon-adaptin),GO:0030659; GO:0006886; GO:0030117; GO:0016192,cytoplasmic vesicle membrane; intracellular protein transport; membrane coat; vesicle-mediated transport,PF01602;,,,,,,,,,AP4E_DICDI,Dictyostelium discoideum (Slime mold),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp139664_c2_seq1,2577,36.1273,0.36907835,57,136,,4.00E-12,Q80V94,AP-4 complex subunit epsilon-1 (AP-4 adapter complex subunit epsilon) (Adapter-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin),AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin),GO:0005794; GO:0006886; GO:0030117; GO:0005802; GO:0016192,Golgi apparatus; intracellular protein transport; membrane coat; trans-Golgi network; vesicle-mediated transport,PF01602;PF14807;,,,,,,,,,AP4E1_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp139666_c0_seq1,954,36.6876,0.56492224,992,1041,,3.00E-52,Q8WW35,Tctex1 domain-containing protein 2,Tctex1 domain-containing protein 2,,,PF03645;,9.00E-55,CHOYP_LOC100180883.1.1,1.00E-81,ruditapes_c9725,,,,,TC1D2_HUMAN,Homo sapiens (Human), comp139669_c0_seq1,1759,38.6015,0.61302702,6,83,,3.00E-11,Q7S3M5,Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),Palmitoyltransferase akr1 (EC 2.3.1.225) (Ankyrin repeat-containing protein akr1) (Palmitoyltransferase 1),GO:0000139; GO:0031901; GO:0016021; GO:0016746; GO:0008270,"Golgi membrane; early endosome membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,,,,,,,,,AKR1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), comp139669_c0_seq2,1462,39.6033,0.63973405,0,0,,3.00E-11,Q8Q0U0,Putative ankyrin repeat protein MM_0045,Putative ankyrin repeat protein MM_0045,,,PF12796;,,,,,,,,,Y045_METMA,Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia), comp139670_c0_seq2,411,37.4696,0.55600869,23,326,,3.00E-31,Q3B7M7,Unconventional prefoldin RPB5 interactor (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein),Unconventional prefoldin RPB5 interactor (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein),GO:0005665; GO:0001106; GO:0071363; GO:0071383; GO:0003682; GO:0005737; GO:0030425; GO:0005739; GO:2001243; GO:0010923; GO:0016272; GO:0006457; GO:0004864; GO:0001558; GO:0009615,"DNA-directed RNA polymerase II, core complex; RNA polymerase II transcription corepressor activity; cellular response to growth factor stimulus; cellular response to steroid hormone stimulus; chromatin binding; cytoplasm; dendrite; mitochondrion; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of phosphatase activity; prefoldin complex; protein folding; protein phosphatase inhibitor activity; regulation of cell growth; response to virus",PF02996;,8.00E-32,CHOYP_LOC100371571.1.1,,,,,,,RMP_BOVIN,Bos taurus (Bovine),"cellular response to growth factor stimulus [GO:0071363]; cellular response to steroid hormone stimulus [GO:0071383]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cell growth [GO:0001558]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]" comp139671_c0_seq1,1347,36.0802,0.3294407,538,325,,1.00E-97,Q8IXY8,Peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL6) (Rotamase PPIL6),Peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL6) (Rotamase PPIL6),GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,7.00E-102,CHOYP_BRAFLDRAFT_281480.1.1,9.00E-118,ruditapes_c13035,,,,,PPIL6_HUMAN,Homo sapiens (Human),protein folding [GO:0006457] comp139672_c0_seq1,1270,42.4409,0.6300921,282,2351,,,,,,,,,2.00E-20,CHOYP_LOC584416.1.1,,,,,,,,, comp139677_c0_seq1,1286,41.7574,0.31091393,147,699,,7.00E-52,O55230,DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3),DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3),GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0008094; GO:0005634,ATP binding; DNA binding; DNA recombination; DNA repair; DNA-dependent ATPase activity; nucleus,PF08423;,,,,,,,,,RA51D_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; meiotic DNA recombinase assembly [GO:0000707]; mitotic recombination [GO:0006312]; nucleotide-excision repair [GO:0006289]; reciprocal meiotic recombination [GO:0007131]; regulation of cell cycle [GO:0051726]; response to ionizing radiation [GO:0010212]; strand invasion [GO:0042148]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp139677_c4_seq1,7547,40.8374,0.44519868,13,9,,9.00E-136,O60293,Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2),Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2),GO:0006396; GO:0005622; GO:0046872,RNA processing; intracellular; metal ion binding,PF10650;,,,,,,,,,ZC3H1_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp139677_c4_seq3,7500,40.96,0.44217092,14,32,,8.00E-136,O60293,Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2),Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2),GO:0006396; GO:0005622; GO:0046872,RNA processing; intracellular; metal ion binding,PF10650;,,,,,,,,,ZC3H1_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp139678_c1_seq1,693,39.9711,0.50683465,8,55,,1.00E-62,Q9Y3A2,Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein),Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein),GO:0005737; GO:0097194; GO:0005615; GO:0007399; GO:0048011; GO:0005730; GO:0005634; GO:2001272; GO:0006364; GO:0032040,cytoplasm; execution phase of apoptosis; extracellular space; nervous system development; neurotrophin TRK receptor signaling pathway; nucleolus; nucleus; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; rRNA processing; small-subunit processome,PF03998;,5.00E-44,CHOYP_ISCW_ISCW020956.1.1,,,,,,,UTP11_HUMAN,Homo sapiens (Human),nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] comp139678_c1_seq2,1085,36.8664,0.32789883,42,245,,3.00E-38,Q9W3C0,Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11),Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11),GO:0022008; GO:0005730; GO:0006364; GO:0032040; GO:0006412,neurogenesis; nucleolus; rRNA processing; small-subunit processome; translation,PF03998;,,,,,,,,,UTP11_DROME,Drosophila melanogaster (Fruit fly),neurogenesis [GO:0022008]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] comp139679_c1_seq1,1302,42.2427,0.6414773,103,203,,3.00E-91,O15297,Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1),Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1),GO:0000086; GO:0046872; GO:0008285; GO:0005634; GO:0035970; GO:0004722; GO:0009617; GO:0009314,G2/M transition of mitotic cell cycle; metal ion binding; negative regulation of cell proliferation; nucleus; peptidyl-threonine dephosphorylation; protein serine/threonine phosphatase activity; response to bacterium; response to radiation,PF00481;,2.00E-115,CHOYP_LOC100644827.1.1,,,,,,,PPM1D_HUMAN,Homo sapiens (Human),cellular response to starvation [GO:0009267]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of cell proliferation [GO:0008285]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; response to bacterium [GO:0009617]; response to radiation [GO:0009314] comp139679_c1_seq2,768,41.6667,0.39949716,1,7,,2.00E-26,O15297,Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1),Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1),GO:0000086; GO:0046872; GO:0008285; GO:0005634; GO:0035970; GO:0004722; GO:0009617; GO:0009314,G2/M transition of mitotic cell cycle; metal ion binding; negative regulation of cell proliferation; nucleus; peptidyl-threonine dephosphorylation; protein serine/threonine phosphatase activity; response to bacterium; response to radiation,PF00481;,,,,,,,,,PPM1D_HUMAN,Homo sapiens (Human),cellular response to starvation [GO:0009267]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of cell proliferation [GO:0008285]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; response to bacterium [GO:0009617]; response to radiation [GO:0009314] comp139681_c1_seq1,1005,35.8209,0.50910982,62,48,,,,,,,,,,,3.00E-33,ruditapes_c10300,,,,,,, comp139681_c4_seq1,2113,41.505,0.50370656,0,0,,3.00E-39,O44757,Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59),Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59),GO:0003677; GO:0001715; GO:0009792; GO:0048566; GO:0034968; GO:0018024; GO:0040011; GO:0002119; GO:0005634; GO:0018991; GO:0045944; GO:0040014; GO:0045138; GO:0006351; GO:0008270,"DNA binding; ectodermal cell fate specification; embryo development ending in birth or egg hatching; embryonic digestive tract development; histone lysine methylation; histone-lysine N-methyltransferase activity; locomotion; nematode larval development; nucleus; oviposition; positive regulation of transcription from RNA polymerase II promoter; regulation of multicellular organism growth; tail tip morphogenesis; transcription, DNA-dependent; zinc ion binding",PF01426;PF00628;PF00856;,1.00E-70,CHOYP_ASH1L.1.2,,,,,,,LIN59_CAEEL,Caenorhabditis elegans,"ectodermal cell fate specification [GO:0001715]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; transcription, DNA-templated [GO:0006351]" comp139681_c4_seq4,3353,42.4396,0.50957772,0,0,,0,Q99MY8,Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (Absent small and homeotic disks protein 1 homolog),Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (Absent small and homeotic disks protein 1 homolog),GO:0003677; GO:0005694; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0005923; GO:0006351; GO:0008270,"DNA binding; chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; tight junction; transcription, DNA-dependent; zinc ion binding",PF01426;PF00439;PF00856;,,,,,,,,,ASH1L_MOUSE,Mus musculus (Mouse),"histone H3-K36 dimethylation [GO:0097676]; histone H3-K4 methylation [GO:0051568]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp139681_c4_seq5,2896,43.8191,0.50237253,0,0,,0,Q99MY8,Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (Absent small and homeotic disks protein 1 homolog),Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (Absent small and homeotic disks protein 1 homolog),GO:0003677; GO:0005694; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0005923; GO:0006351; GO:0008270,"DNA binding; chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; tight junction; transcription, DNA-dependent; zinc ion binding",PF01426;PF00439;PF00856;,,,,,,,,,ASH1L_MOUSE,Mus musculus (Mouse),"histone H3-K36 dimethylation [GO:0097676]; histone H3-K4 methylation [GO:0051568]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp139681_c4_seq6,1734,41.1765,0.51593761,0,0,,3.00E-18,Q90941,Protein polybromo-1,Protein polybromo-1,GO:0003677; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,8.00E-71,CHOYP_ASH1L.1.2,,,,,,,PB1_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139681_c4_seq7,1656,43.6594,0.49103206,0,0,,9.00E-08,Q9UTN6,Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21),Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21),GO:0005524; GO:0004003; GO:0003677; GO:0016586; GO:0006338; GO:0000991; GO:0000790,ATP binding; ATP-dependent DNA helicase activity; DNA binding; RSC complex; chromatin remodeling; core RNA polymerase II binding transcription factor activity; nuclear chromatin,PF00439;PF00271;PF07529;PF14619;PF00176;,,,,,,,,,SNF21_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338]; transcription from RNA polymerase II promoter [GO:0006366] comp139681_c4_seq8,1277,43.8528,0.50259587,0,0,,5.00E-40,O44757,Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59),Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59),GO:0003677; GO:0001715; GO:0009792; GO:0048566; GO:0034968; GO:0018024; GO:0040011; GO:0002119; GO:0005634; GO:0018991; GO:0045944; GO:0040014; GO:0045138; GO:0006351; GO:0008270,"DNA binding; ectodermal cell fate specification; embryo development ending in birth or egg hatching; embryonic digestive tract development; histone lysine methylation; histone-lysine N-methyltransferase activity; locomotion; nematode larval development; nucleus; oviposition; positive regulation of transcription from RNA polymerase II promoter; regulation of multicellular organism growth; tail tip morphogenesis; transcription, DNA-dependent; zinc ion binding",PF01426;PF00628;PF00856;,6.00E-71,CHOYP_ASH1L.1.2,,,,,,,LIN59_CAEEL,Caenorhabditis elegans,"ectodermal cell fate specification [GO:0001715]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; transcription, DNA-templated [GO:0006351]" comp139682_c0_seq1,1268,35.9621,0.58597439,961,2002,,2.00E-24,Q9W021,"39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23)","39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23)",GO:0005762; GO:0000166; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; nucleotide binding; structural constituent of ribosome; translation,PF00276;,,,,,,,,,RM23_DROME,Drosophila melanogaster (Fruit fly),mitochondrial translation [GO:0032543]; translation [GO:0006412] comp139682_c0_seq2,1894,40.4435,0.74367469,134,203,,0,Q5BKL0,4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase),4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase),GO:0003868; GO:0006559; GO:0046872; GO:0006572,4-hydroxyphenylpyruvate dioxygenase activity; L-phenylalanine catabolic process; metal ion binding; tyrosine catabolic process,PF00903;,,,,,,,,,HPPD_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp139682_c0_seq3,1327,43.5569,0.67170095,96,381,,0,Q5EA20,4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase),4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase),GO:0003868; GO:0006559; GO:0046872; GO:0006572,4-hydroxyphenylpyruvate dioxygenase activity; L-phenylalanine catabolic process; metal ion binding; tyrosine catabolic process,PF00903;,5.00E-155,CHOYP_LOC594130.1.1,,,,,,,HPPD_BOVIN,Bos taurus (Bovine),L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp139688_c1_seq2,1060,38.0189,0.53748781,123,303,,3.00E-29,Q642A0,p53 and DNA damage-regulated protein 1,p53 and DNA damage-regulated protein 1,GO:0016272; GO:0006457,prefoldin complex; protein folding,PF01920;,,,,,,,,,PDRG1_RAT,Rattus norvegicus (Rat),protein folding [GO:0006457] comp139689_c0_seq1,1835,41.1989,0.47334851,0,0,,,,,,,,,2.00E-34,CHOYP_LOC100376540.1.1,,,,,,,,, comp139689_c0_seq3,1274,40.2669,0.47822991,0,0,,1.00E-26,Q8C9M2,Coiled-coil domain-containing protein 15,Coiled-coil domain-containing protein 15,GO:0005813,centrosome,,,,,,,,,,CCD15_MOUSE,Mus musculus (Mouse), comp139689_c0_seq8,1262,40.0951,0.447008,0,0,,1.00E-26,Q8C9M2,Coiled-coil domain-containing protein 15,Coiled-coil domain-containing protein 15,GO:0005813,centrosome,,1.00E-34,CHOYP_LOC100376540.1.1,,,,,,,CCD15_MOUSE,Mus musculus (Mouse), comp139692_c1_seq1,3761,47.4608,0.56285789,0,0,,0,Q9W7R4,Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3),Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3),GO:0030424; GO:0007156; GO:0016021; GO:0016020; GO:0010976; GO:0046982; GO:0042803; GO:0007165,axon; homophilic cell adhesion; integral to membrane; membrane; positive regulation of neuron projection development; protein heterodimerization activity; protein homodimerization activity; signal transduction,PF12661;PF06484;PF15636;,9.00E-100,CHOYP_TEN2.1.2,,,,,,,TEN3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),dendrite guidance [GO:0070983]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of neuron projection development [GO:0010976]; retinal ganglion cell axon guidance [GO:0031290]; self proteolysis [GO:0097264]; signal transduction [GO:0007165] comp139692_c1_seq2,4117,47.6075,0.55783704,0,0,,3.00E-08,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,6.00E-109,CHOYP_TEN2.2.2,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp139692_c1_seq3,3935,47.7001,0.56386996,0,0,,0,Q9NT68,"Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]","Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]",GO:0005794; GO:0016605; GO:0007411; GO:0035584; GO:0050839; GO:0030054; GO:0016337; GO:0005911; GO:0043197; GO:0005783; GO:0030175; GO:0030426; GO:0007157; GO:0005887; GO:0000122; GO:0005886; GO:0051491; GO:0045211; GO:0046982; GO:0042803; GO:0005102; GO:0007165; GO:0006351,"Golgi apparatus; PML body; axon guidance; calcium-mediated signaling using intracellular calcium source; cell adhesion molecule binding; cell junction; cell-cell adhesion; cell-cell junction; dendritic spine; endoplasmic reticulum; filopodium; growth cone; heterophilic cell-cell adhesion; integral to plasma membrane; negative regulation of transcription from RNA polymerase II promoter; plasma membrane; positive regulation of filopodium assembly; postsynaptic membrane; protein heterodimerization activity; protein homodimerization activity; receptor binding; signal transduction; transcription, DNA-dependent",PF06484;PF15636;,,,,,,,,,TEN2_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]" comp139692_c1_seq4,4396,47.7025,0.55641915,0,0,,3.00E-07,P10041,Neurogenic locus protein delta,Neurogenic locus protein delta,GO:0005112; GO:0007219; GO:0007464; GO:0007460; GO:0007015; GO:0005912; GO:0048800; GO:0007475; GO:0008356; GO:0007298; GO:0005509; GO:0007155; GO:0001708; GO:0009986; GO:0008407; GO:0042676; GO:0046667; GO:0007451; GO:0007398; GO:0030139; GO:0005768; GO:0030718; GO:0008347; GO:0036011; GO:0007474; GO:0016021; GO:0046331; GO:0007498; GO:0035157; GO:0050768; GO:0035155; GO:0016318; GO:0007314; GO:0030720; GO:0007424; GO:0030713; GO:0007422; GO:0008284; GO:0045931; GO:0045468; GO:0016330; GO:0035003; GO:0007419; GO:0048190,"Notch binding; Notch signaling pathway; R3/R4 cell fate commitment; R8 cell fate commitment; actin filament organization; adherens junction; antennal morphogenesis; apposition of dorsal and ventral imaginal disc-derived wing surfaces; asymmetric cell division; border follicle cell migration; calcium ion binding; cell adhesion; cell fate specification; cell surface; chaeta morphogenesis; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; endocytic vesicle; endosome; germ-line stem cell maintenance; glial cell migration; imaginal disc-derived leg segmentation; imaginal disc-derived wing vein specification; integral to membrane; lateral inhibition; mesoderm development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; ommatidial rotation; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; open tracheal system development; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of cell proliferation; positive regulation of mitotic cell cycle; regulation of R8 cell spacing in compound eye; second mitotic wave involved in compound eye morphogenesis; subapical complex; ventral cord development; wing disc dorsal/ventral pattern formation",PF01414;PF00008;PF07657;,0,CHOYP_TEN2.2.2,,,,,,,DL_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; asymmetric cell division [GO:0008356]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; ectoderm development [GO:0007398]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; lateral inhibition [GO:0046331]; mesoderm development [GO:0007498]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; ommatidial rotation [GO:0016318]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; R3/R4 cell fate commitment [GO:0007464]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of R8 cell spacing in compound eye [GO:0045468]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory perception of pain [GO:0019233]; sleep [GO:0030431]; stem cell differentiation [GO:0048863]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]" comp139692_c1_seq5,3656,47.593,0.56605717,0,0,,4.00E-31,P10039,Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C),Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF07974;PF00147;PF00041;PF12661;,2.00E-12,CHOYP_TEN4.1.1,,,,,,,TENA_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; regulation of cell proliferation [GO:0042127] comp139692_c1_seq7,4222,47.4893,0.55513997,0,0,,3.00E-06,P18168,Protein serrate (Protein beaded),Protein serrate (Protein beaded),GO:0005112; GO:0007219; GO:0016324; GO:0030673; GO:0005509; GO:0009986; GO:0048749; GO:0035017; GO:0007451; GO:0035214; GO:0030718; GO:0036011; GO:0007476; GO:0016021; GO:0007436; GO:0046331; GO:0035170; GO:0045746; GO:0042689,"Notch binding; Notch signaling pathway; apical plasma membrane; axolemma; calcium ion binding; cell surface; compound eye development; cuticle pattern formation; dorsal/ventral lineage restriction, imaginal disc; eye-antennal disc development; germ-line stem cell maintenance; imaginal disc-derived leg segmentation; imaginal disc-derived wing morphogenesis; integral to membrane; larval salivary gland morphogenesis; lateral inhibition; lymph gland crystal cell differentiation; negative regulation of Notch signaling pathway; regulation of crystal cell differentiation",PF01414;PF00008;PF07645;PF12661;PF07657;,,,,,,,,,SERR_DROME,Drosophila melanogaster (Fruit fly),"compound eye development [GO:0048749]; crystal cell differentiation [GO:0042688]; cuticle pattern formation [GO:0035017]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; eye-antennal disc development [GO:0035214]; germ-line stem cell population maintenance [GO:0030718]; glial cell proliferation [GO:0014009]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived wing morphogenesis [GO:0007476]; larval lymph gland hemopoiesis [GO:0035167]; larval salivary gland morphogenesis [GO:0007436]; lateral inhibition [GO:0046331]; lymph gland crystal cell differentiation [GO:0035170]; negative regulation of Notch signaling pathway [GO:0045746]; Notch signaling pathway [GO:0007219]; regulation of crystal cell differentiation [GO:0042689]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]" comp139692_c1_seq8,4040,47.5495,0.55713489,0,0,,0,Q9NT68,"Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]","Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]",GO:0005794; GO:0016605; GO:0007411; GO:0035584; GO:0050839; GO:0030054; GO:0016337; GO:0005911; GO:0043197; GO:0005783; GO:0030175; GO:0030426; GO:0007157; GO:0005887; GO:0000122; GO:0005886; GO:0051491; GO:0045211; GO:0046982; GO:0042803; GO:0005102; GO:0007165; GO:0006351,"Golgi apparatus; PML body; axon guidance; calcium-mediated signaling using intracellular calcium source; cell adhesion molecule binding; cell junction; cell-cell adhesion; cell-cell junction; dendritic spine; endoplasmic reticulum; filopodium; growth cone; heterophilic cell-cell adhesion; integral to plasma membrane; negative regulation of transcription from RNA polymerase II promoter; plasma membrane; positive regulation of filopodium assembly; postsynaptic membrane; protein heterodimerization activity; protein homodimerization activity; receptor binding; signal transduction; transcription, DNA-dependent",PF06484;PF15636;,0,CHOYP_TEN2.2.2,,,,,,,TEN2_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]" comp139692_c1_seq9,4501,47.5672,0.55050426,0,0,,0,Q9NT68,"Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]","Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]",GO:0005794; GO:0016605; GO:0007411; GO:0035584; GO:0050839; GO:0030054; GO:0016337; GO:0005911; GO:0043197; GO:0005783; GO:0030175; GO:0030426; GO:0007157; GO:0005887; GO:0000122; GO:0005886; GO:0051491; GO:0045211; GO:0046982; GO:0042803; GO:0005102; GO:0007165; GO:0006351,"Golgi apparatus; PML body; axon guidance; calcium-mediated signaling using intracellular calcium source; cell adhesion molecule binding; cell junction; cell-cell adhesion; cell-cell junction; dendritic spine; endoplasmic reticulum; filopodium; growth cone; heterophilic cell-cell adhesion; integral to plasma membrane; negative regulation of transcription from RNA polymerase II promoter; plasma membrane; positive regulation of filopodium assembly; postsynaptic membrane; protein heterodimerization activity; protein homodimerization activity; receptor binding; signal transduction; transcription, DNA-dependent",PF06484;PF15636;,0,CHOYP_TEN2.1.2,,,,,,,TEN2_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]" comp139694_c0_seq1,2494,41.4194,0.60105319,159,1119,,8.00E-117,P10155,60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2),60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2),GO:0003723; GO:0060271; GO:0005737; GO:0046872; GO:0005634; GO:0030529; GO:0006383,RNA binding; cilium morphogenesis; cytoplasm; metal ion binding; nucleus; ribonucleoprotein complex; transcription from RNA polymerase III promoter,PF05731;,,,,,,,,,RO60_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]; transcription from RNA polymerase III promoter [GO:0006383] comp139694_c0_seq3,1505,39.0033,0.49808668,29,141,,7.00E-59,P10155,60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2),60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2),GO:0003723; GO:0060271; GO:0005737; GO:0046872; GO:0005634; GO:0030529; GO:0006383,RNA binding; cilium morphogenesis; cytoplasm; metal ion binding; nucleus; ribonucleoprotein complex; transcription from RNA polymerase III promoter,PF05731;,,,1.00E-53,ruditapes2_c134,,,,,RO60_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]; transcription from RNA polymerase III promoter [GO:0006383] comp139697_c0_seq1,419,48.4487,0.49190208,59,11,,8.00E-66,B4F6W9,E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),GO:0006281; GO:0009790; GO:2000780; GO:1901315; GO:0005654; GO:0042787; GO:0006974; GO:0004842,DNA repair; embryo development; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity,PF00632;PF02825;,6.00E-65,CHOYP_TRIPC.1.1,,,,,,,TRIPC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp139697_c0_seq2,756,49.2063,0.46176047,0,4,,4.00E-14,G5E870,E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),GO:0006281; GO:0005737; GO:0009790; GO:2000780; GO:1901315; GO:0005654; GO:0042787; GO:0006974; GO:0004842,DNA repair; cytoplasm; embryo development; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity,PF00632;PF02825;,,,,,,,,,TRIPC_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp139698_c1_seq1,2559,37.9836,0.3878587,114,190,,0,P53992,Protein transport protein Sec24C (SEC24-related protein C),Protein transport protein Sec24C (SEC24-related protein C),GO:0030127; GO:0048208; GO:0000139; GO:0019886; GO:0002474; GO:0005829; GO:0005789; GO:0006886; GO:0005634; GO:0048471; GO:0043687; GO:0018279; GO:0044281; GO:0008270,COPII vesicle coat; COPII vesicle coating; Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; cytosol; endoplasmic reticulum membrane; intracellular protein transport; nucleus; perinuclear region of cytoplasm; post-translational protein modification; protein N-linked glycosylation via asparagine; small molecule metabolic process; zinc ion binding,PF00626;PF08033;PF04815;PF04811;PF04810;,0,CHOYP_SEC24C.1.1,,,,,,,SC24C_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886] comp139701_c0_seq1,825,39.0303,1.02640722,2915,9,male>female,1.00E-15,Q9P1V8,Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15),Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15),,,PF07647;,,,,,,,,,SAM15_HUMAN,Homo sapiens (Human), comp139701_c1_seq4,896,28.3482,0.16721577,0,0,,,,,,,,,,,5.00E-11,ruditapes_c17805,,,,,,, comp139702_c1_seq2,522,40.2299,0.85582132,11,217,,6.00E-09,Q9BXX0,EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10),EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10),GO:0007155; GO:0005581; GO:0030023; GO:0005576,cell adhesion; collagen; extracellular matrix constituent conferring elasticity; extracellular region,PF00386;PF07546;,,,,,,,,,EMIL2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp139704_c1_seq4,1529,40.7456,0.36987613,442,1035,,2.00E-78,P82933,"28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt)","28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt)",GO:0042769; GO:0005763; GO:0043043; GO:0003735; GO:0006412,"DNA damage response, detection of DNA damage; mitochondrial small ribosomal subunit; peptide biosynthetic process; structural constituent of ribosome; translation",PF00380;,,,,,,,,,RT09_HUMAN,Homo sapiens (Human),"DNA damage response, detection of DNA damage [GO:0042769]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]" comp139706_c0_seq2,2669,39.2282,0.23472875,3,0,,8.00E-121,Q7Z5Q5,DNA polymerase nu (EC 2.7.7.7),DNA polymerase nu (EC 2.7.7.7),GO:0003677; GO:0006281; GO:0006260; GO:0003887; GO:0005634,DNA binding; DNA repair; DNA replication; DNA-directed DNA polymerase activity; nucleus,PF00476;,,,,,,,,,DPOLN_HUMAN,Homo sapiens (Human),DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; translesion synthesis [GO:0019985] comp139706_c0_seq3,2015,38.8586,0.2636501,38,29,,5.00E-59,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,2.00E-60,CHOYP_POLN.1.1,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp139707_c0_seq1,3465,39.8846,0.64956135,116,624,,1.00E-177,Q5RDQ2,MAGUK p55 subfamily member 5,MAGUK p55 subfamily member 5,GO:0012505; GO:0005886; GO:0005923,endomembrane system; plasma membrane; tight junction,PF00625;PF02828;PF09060;PF00595;PF07653;,6.00E-108,CHOYP_LOC100158931.1.1,9.00E-97,ruditapes_c610,,,,,MPP5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),bicellular tight junction assembly [GO:0070830]; establishment of epithelial cell polarity [GO:0090162] comp139707_c2_seq1,1297,46.4148,0.93205977,5,42,,4.00E-16,Q8BGW8,Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1),Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1),GO:0005737; GO:0005634; GO:0045944; GO:0007519; GO:0003713; GO:0006351,"cytoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; skeletal muscle tissue development; transcription coactivator activity; transcription, DNA-dependent",PF07545;,,,,,,,,,VGLL2_MOUSE,Mus musculus (Mouse),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp139707_c2_seq2,1391,46.5133,0.93188778,0,71,,8.00E-10,Q26366,Protein vestigial,Protein vestigial,GO:0003677; GO:0006260; GO:0007049; GO:0001745; GO:0016204; GO:0007451; GO:0007482; GO:0007480; GO:0008587; GO:0005634; GO:0045944; GO:0042127; GO:0007346; GO:0007525; GO:0006351; GO:0048190; GO:0007473,"DNA binding; DNA replication; cell cycle; compound eye morphogenesis; determination of muscle attachment site; dorsal/ventral lineage restriction, imaginal disc; haltere development; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; regulation of mitotic cell cycle; somatic muscle development; transcription, DNA-dependent; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF07545;,,,,,,,,,VG_DROME,Drosophila melanogaster (Fruit fly),"cell cycle [GO:0007049]; compound eye morphogenesis [GO:0001745]; determination of muscle attachment site [GO:0016204]; DNA replication [GO:0006260]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; haltere development [GO:0007482]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell proliferation [GO:0042127]; regulation of imaginal disc-derived wing size [GO:0044719]; regulation of mitotic cell cycle [GO:0007346]; somatic muscle development [GO:0007525]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc morphogenesis [GO:0007472]; wing disc proximal/distal pattern formation [GO:0007473]" comp139712_c0_seq1,1514,37.6486,0.37370054,216,3857,,3.00E-146,B0BNE5,S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D),S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D),GO:0005794; GO:0018738; GO:0004091; GO:0016023; GO:0046294; GO:0005634,Golgi apparatus; S-formylglutathione hydrolase activity; carboxylesterase activity; cytoplasmic membrane-bounded vesicle; formaldehyde catabolic process; nucleus,PF00756;,4.00E-106,CHOYP_BRAFLDRAFT_79044.2.2,,,,,,,ESTD_RAT,Rattus norvegicus (Rat),formaldehyde catabolic process [GO:0046294] comp139713_c1_seq1,1263,46.0808,0.33537173,6,15,,2.00E-124,Q96FC9,Probable ATP-dependent RNA helicase DDX11 (EC 3.6.4.13) (CHL1-related protein 1) (hCHLR1) (DEAD/H box protein 11) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2),Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (CHL1-related protein 1) (hCHLR1) (DEAD/H box protein 11) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0003678; GO:0008094; GO:0000086; GO:0003723; GO:0006987; GO:0044267; GO:0046872; GO:0030496; GO:0000084; GO:0000070; GO:0019048; GO:0000790; GO:0005730; GO:0005654; GO:0008284; GO:0007062; GO:0000922,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA helicase activity; DNA-dependent ATPase activity; G2/M transition of mitotic cell cycle; RNA binding; activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; metal ion binding; midbody; mitotic S phase; mitotic sister chromatid segregation; modulation by virus of host morphology or physiology; nuclear chromatin; nucleolus; nucleoplasm; positive regulation of cell proliferation; sister chromatid cohesion; spindle pole",PF06733;PF13307;,,,,,,,,,DDX11_HUMAN,Homo sapiens (Human),IRE1-mediated unfolded protein response [GO:0036498]; nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032] comp139713_c1_seq2,1605,42.4299,0.33849139,67,120,,3.00E-153,Q6AXC6,Probable ATP-dependent RNA helicase DDX11 (EC 3.6.4.13) (DEAD/H box protein 11),Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H box protein 11),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0008094; GO:0003723; GO:0004386; GO:0046872; GO:0030496; GO:0000790; GO:0005730; GO:0007062; GO:0000922,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA-dependent ATPase activity; RNA binding; helicase activity; metal ion binding; midbody; nuclear chromatin; nucleolus; sister chromatid cohesion; spindle pole",PF06733;PF13307;,5.00E-73,CHOYP_DDX11.1.1,,,,,,,DDX11_MOUSE,Mus musculus (Mouse),nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062] comp139713_c1_seq4,617,47.1637,0.30193552,0,0,,5.00E-34,A3LN13,ATP-dependent RNA helicase CHL1 (EC 3.6.4.13) (Chromosome loss protein 1),ATP-dependent DNA helicase CHL1 (EC 3.6.4.12) (Chromosome loss protein 1),GO:0005524; GO:0004003; GO:0003677; GO:0007049; GO:0005634,ATP binding; ATP-dependent DNA helicase activity; DNA binding; cell cycle; nucleus,PF06733;PF13307;,,,,,,,,,CHL1_PICST,Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis),DNA replication initiation [GO:0006270]; donor selection [GO:0007535]; establishment of sister chromatid cohesion [GO:0034085]; interstrand cross-link repair [GO:0036297]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of DNA recombination [GO:0045910] comp139713_c1_seq5,573,43.9791,0.3983357,14,56,,1.00E-70,Q6AXC6,Probable ATP-dependent RNA helicase DDX11 (EC 3.6.4.13) (DEAD/H box protein 11),Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H box protein 11),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0008094; GO:0003723; GO:0004386; GO:0046872; GO:0030496; GO:0000790; GO:0005730; GO:0007062; GO:0000922,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA-dependent ATPase activity; RNA binding; helicase activity; metal ion binding; midbody; nuclear chromatin; nucleolus; sister chromatid cohesion; spindle pole",PF06733;PF13307;,,,,,,,,,DDX11_MOUSE,Mus musculus (Mouse),nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062] comp139715_c0_seq1,1800,44.8333,0.48026086,532,1292,,2.00E-162,O08651,D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95),D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95),GO:0006564; GO:0051287; GO:0004617; GO:0009070,L-serine biosynthetic process; NAD binding; phosphoglycerate dehydrogenase activity; serine family amino acid biosynthetic process,PF00389;PF02826;,5.00E-99,CHOYP_LOC590971.1.1,,,,,,,SERA_RAT,Rattus norvegicus (Rat),G1 to G0 transition [GO:0070314]; gamma-aminobutyric acid metabolic process [GO:0009448]; glial cell development [GO:0021782]; glutamine metabolic process [GO:0006541]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; neural tube development [GO:0021915]; neuron projection development [GO:0031175]; regulation of gene expression [GO:0010468]; serine family amino acid biosynthetic process [GO:0009070]; spinal cord development [GO:0021510]; taurine metabolic process [GO:0019530]; threonine metabolic process [GO:0006566] comp139716_c0_seq1,980,48.4694,0.96063555,118,626,,3.00E-19,Q9EQD0,Frizzled-5 (Fz-5) (mFz5),Frizzled-5 (Fz-5) (mFz5),GO:0004930; GO:0005794; GO:0000139; GO:0030165; GO:0060061; GO:0033077; GO:0044332; GO:0042813; GO:0001525; GO:0008595; GO:0060561; GO:0007409; GO:0007420; GO:0060670; GO:0060070; GO:0048469; GO:0042995; GO:0009986; GO:0071219; GO:0060718; GO:0031076; GO:0008406; GO:0016021; GO:0060716; GO:0008285; GO:0048471; GO:0005886; GO:0043507; GO:0032729; GO:0045944; GO:0031077; GO:0060828; GO:1901382; GO:2000810; GO:0060715; GO:0005923,"G-protein coupled receptor activity; Golgi apparatus; Golgi membrane; PDZ domain binding; Spemann organizer formation; T cell differentiation in thymus; Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; angiogenesis; anterior/posterior axis specification, embryo; apoptotic process involved in morphogenesis; axonogenesis; brain development; branching involved in labyrinthine layer morphogenesis; canonical Wnt receptor signaling pathway; cell maturation; cell projection; cell surface; cellular response to molecule of bacterial origin; chorionic trophoblast cell differentiation; embryonic camera-type eye development; gonad development; integral to membrane; labyrinthine layer blood vessel development; negative regulation of cell proliferation; perinuclear region of cytoplasm; plasma membrane; positive regulation of JUN kinase activity; positive regulation of interferon-gamma production; positive regulation of transcription from RNA polymerase II promoter; post-embryonic camera-type eye development; regulation of canonical Wnt receptor signaling pathway; regulation of chorionic trophoblast cell proliferation; regulation of tight junction assembly; syncytiotrophoblast cell differentiation involved in labyrinthine layer development; tight junction",PF01534;PF01392;,,,,,,,,,FZD5_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; anterior/posterior axis specification, embryo [GO:0008595]; apoptotic process involved in morphogenesis [GO:0060561]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; canonical Wnt signaling pathway [GO:0060070]; cell maturation [GO:0048469]; cellular response to molecule of bacterial origin [GO:0071219]; chorionic trophoblast cell differentiation [GO:0060718]; embryonic axis specification [GO:0000578]; embryonic camera-type eye development [GO:0031076]; embryonic camera-type eye morphogenesis [GO:0048596]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic camera-type eye development [GO:0031077]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of chorionic trophoblast cell proliferation [GO:1901382]; regulation of mitophagy [GO:1903146]; Spemann organizer formation [GO:0060061]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell differentiation in thymus [GO:0033077]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp139716_c1_seq1,1126,31.0835,0.58910824,21,50,,,,,,,,,,,1.00E-14,ruditapes_c13570,,,,,,, comp139718_c0_seq1,1934,38.6763,0.95952508,5,7,,,,,,,,,1.00E-18,CHOYP_BRAFLDRAFT_120654.1.1,,,,,,,,, comp139719_c0_seq1,1017,33.9233,0.24290997,161,929,,6.00E-28,Q5RBX7,Signal recognition particle 14 kDa protein (SRP14),Signal recognition particle 14 kDa protein (SRP14),GO:0008312; GO:0006614; GO:0030942; GO:0042493; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; endoplasmic reticulum signal peptide binding; response to drug; signal recognition particle, endoplasmic reticulum targeting",PF02290;,3.00E-42,CHOYP_ISCW_ISCW012442.1.1,2.00E-67,ruditapes_c7002,,,,,SRP14_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp139720_c1_seq1,1378,37.7358,0.77891117,2,40,,9.00E-07,Q91Y77,Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1),Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1),GO:0016323; GO:0016021; GO:0055085,basolateral plasma membrane; integral to membrane; transmembrane transport,PF07690;,,,,,,,,,MOT10_RAT,Rattus norvegicus (Rat),ion transmembrane transport [GO:0034220] comp139720_c1_seq3,2645,38.6011,0.91540213,0,0,,9.00E-31,Q6ZSM3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_HUMAN,Homo sapiens (Human),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp139720_c1_seq4,2272,38.0722,0.89984182,0,0,,2.00E-23,Q6ZSM3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_HUMAN,Homo sapiens (Human),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp139722_c4_seq2,2337,39.2383,0.58333344,25,52,,8.00E-27,Q52M93,Zinc finger protein 585B (zinc finger protein 41-like protein),Zinc finger protein 585B (zinc finger protein 41-like protein),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,Z585B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139722_c4_seq3,2394,39.5155,0.59280054,41,106,,3.00E-28,Q5R633,Zinc finger and BTB domain-containing protein 48,Zinc finger and BTB domain-containing protein 48,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT48_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139723_c0_seq1,1217,41.9063,0.68035237,230,958,,1.00E-22,Q32PP1,UPF0544 protein C5orf45 homolog,UPF0544 protein C5orf45 homolog,,,PF15749;,,,,,,,,,CE045_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139725_c2_seq1,1874,41.6222,0.56517154,186,1702,,1.00E-111,Q3SZK1,Angio-associated migratory cell protein,Angio-associated migratory cell protein,GO:0001525; GO:0030154; GO:0009986; GO:0005737; GO:0005886; GO:0045766; GO:0010595; GO:0014909,angiogenesis; cell differentiation; cell surface; cytoplasm; plasma membrane; positive regulation of angiogenesis; positive regulation of endothelial cell migration; smooth muscle cell migration,PF00400;,2.00E-35,CHOYP_AAMP.1.1,4.00E-47,ruditapes_c19383,,,,,AAMP_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; ribosomal large subunit biogenesis [GO:0042273]; smooth muscle cell migration [GO:0014909] comp139728_c0_seq2,1643,39.0749,0.89892238,3,121,,1.00E-120,P07098,Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3),Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3),GO:0005576; GO:0008289; GO:0016042; GO:0016615; GO:0006108; GO:0005739; GO:0004806; GO:0006641,extracellular region; lipid binding; lipid catabolic process; malate dehydrogenase activity; malate metabolic process; mitochondrion; triglyceride lipase activity; triglyceride metabolic process,PF00561;,,,,,,,,,LIPG_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; malate metabolic process [GO:0006108]; triglyceride metabolic process [GO:0006641] comp139728_c0_seq3,1333,39.3848,0.87553284,0,35,,,,,,,,,8.00E-13,CHOYP_BRAFLDRAFT_131171.1.1,,,,,,,,, comp139729_c0_seq3,2142,36.1811,0.46458826,15,101,,2.00E-49,Q5ZI51,Poly(ADP-ribose) glycohydrolase ARH3 (EC 3.2.1.143) (ADP-ribosylhydrolase 3) ([Protein ADP-ribosylarginine] hydrolase-like protein 2),Poly(ADP-ribose) glycohydrolase ARH3 (EC 3.2.1.143) (ADP-ribosylhydrolase 3) ([Protein ADP-ribosylarginine] hydrolase-like protein 2),GO:0005737; GO:0046872; GO:0005634; GO:0004649,cytoplasm; metal ion binding; nucleus; poly(ADP-ribose) glycohydrolase activity,PF03747;,3.00E-21,CHOYP_BRAFLDRAFT_241420.1.1,,,,,,,ARHL2_CHICK,Gallus gallus (Chicken), comp139730_c1_seq1,2118,40.2266,0.57259966,117,335,,0,Q9NUQ8,ATP-binding cassette sub-family F member 3,ATP-binding cassette sub-family F member 3,GO:0005524; GO:0006200; GO:0016887; GO:0051607,ATP binding; ATP catabolic process; ATPase activity; defense response to virus,PF00005;PF12848;,4.00E-139,CHOYP_LOC100694648.1.1,,,,,,,ABCF3_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp139734_c0_seq2,1120,39.1071,0.60801951,0,0,,,,,,,,,5.00E-78,CHOYP_LOC100368576.1.1,,,,,,,,, comp139734_c0_seq4,1145,39.214,0.59133172,0,0,,1.00E-08,Q99JL1,Sperm flagellar protein 1,Sperm flagellar protein 1,GO:0035085; GO:0005856,cilium axoneme; cytoskeleton,PF06294;,,,,,,,,,SPEF1_MOUSE,Mus musculus (Mouse), comp139734_c0_seq5,1102,39.2015,0.61499911,0,0,,7.00E-49,Q6DMN8,Spermatogenesis-associated protein 4,Spermatogenesis-associated protein 4,GO:0005737,cytoplasm,PF06294;,,,,,,,,,SPAT4_PANTR,Pan troglodytes (Chimpanzee), comp139734_c0_seq9,1127,39.3079,0.59792096,0,0,,9.00E-47,Q6DMN8,Spermatogenesis-associated protein 4,Spermatogenesis-associated protein 4,GO:0005737,cytoplasm,PF06294;,,,1.00E-70,ruditapes2_c2604,,,,,SPAT4_PANTR,Pan troglodytes (Chimpanzee), comp139736_c2_seq1,404,49.0099,0.83497058,0,0,,4.00E-06,Q6UWY0,Arylsulfatase K (ASK) (EC 3.1.6.-) (Telethon sulfatase),Arylsulfatase K (ASK) (EC 3.1.6.-) (Telethon sulfatase),GO:0004065; GO:0005788; GO:0005576; GO:0006687; GO:0046872; GO:0043687; GO:0044281,arylsulfatase activity; endoplasmic reticulum lumen; extracellular region; glycosphingolipid metabolic process; metal ion binding; post-translational protein modification; small molecule metabolic process,PF00884;,,,,,,,,,ARSK_HUMAN,Homo sapiens (Human),glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687] comp139736_c2_seq2,456,48.4649,0.78962038,0,0,,9.00E-26,Q32KJ9,Arylsulfatase G (ASG) (EC 3.1.6.-),Arylsulfatase G (ASG) (EC 3.1.6.-),GO:0004065; GO:0005783; GO:0005615; GO:0005764; GO:0046872; GO:0006790,arylsulfatase activity; endoplasmic reticulum; extracellular space; lysosome; metal ion binding; sulfur compound metabolic process,PF00884;,,,,,,,,,ARSG_RAT,Rattus norvegicus (Rat),sulfur compound metabolic process [GO:0006790] comp139736_c2_seq3,777,47.7477,0.94994052,0,70,,5.00E-82,P50430,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0007417; GO:0005764; GO:0046872; GO:0005739; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; central nervous system development; lysosome; metal ion binding; mitochondrion; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,7.00E-17,CHOYP_LOC100377677.2.2,,,,,,,ARSB_RAT,Rattus norvegicus (Rat),autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] comp139737_c0_seq3,2632,43.579,0.44387746,146,262,,2.00E-27,Q1L981,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp139738_c0_seq1,1924,40.4886,0.615401,20,15,,,,,,,,,6.00E-124,CHOYP_BRAFLDRAFT_93126.2.3,,,,,,,,, comp139738_c0_seq2,2728,39.7361,0.60223209,102,31,,0,Q8BG51,Mitochondrial Rho GTPase 1 (MIRO-1) (EC 3.6.5.-) (Ras homolog gene family member T1),Mitochondrial Rho GTPase 1 (MIRO-1) (EC 3.6.5.-) (Ras homolog gene family member T1),GO:0005525; GO:0006184; GO:0003924; GO:0005509; GO:0019725; GO:0031307; GO:0097345; GO:0047497; GO:0007264,GTP binding; GTP catabolic process; GTPase activity; calcium ion binding; cellular homeostasis; integral to mitochondrial outer membrane; mitochondrial outer membrane permeabilization; mitochondrion transport along microtubule; small GTPase mediated signal transduction,PF08355;PF08356;PF00071;,,,,,,,,,MIRO1_MOUSE,Mus musculus (Mouse),cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion transport along microtubule [GO:0047497]; small GTPase mediated signal transduction [GO:0007264] comp139739_c0_seq1,1154,40.9012,0.97067763,0,0,,,,,,,,,1.00E-48,CHOYP_LOC100898095.7.19,,,,,,,,, comp139739_c0_seq2,851,40.658,1.03870915,0,0,,,,,,,,,1.00E-13,CHOYP_SCLT1.1.1,,,,,,,,, comp139739_c0_seq3,740,40.9459,1.05857336,0,0,,,,,,,,,8.00E-16,CHOYP_LOC100904451.4.11,,,,,,,,, comp139739_c0_seq4,1738,39.3556,0.94299394,12,19,,,,,,,,,3.00E-13,CHOYP_LOC100904451.11.11,,,,,,,,, comp139739_c0_seq7,1265,40.7115,0.96567566,0,0,,,,,,,,,1.00E-48,CHOYP_LOC100898095.7.19,,,,,,,,, comp139741_c0_seq1,1997,44.6169,0.37118774,2,0,,3.00E-35,Q02241,Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),GO:0005524; GO:0019886; GO:0007596; GO:0097149; GO:0005813; GO:0000910; GO:0005829; GO:0045171; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018; GO:0030496; GO:0000022; GO:0005654; GO:0032467; GO:0051256,ATP binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; centralspindlin complex; centrosome; cytokinesis; cytosol; intercellular bridge; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement; midbody; mitotic spindle elongation; nucleoplasm; positive regulation of cytokinesis; spindle midzone assembly involved in mitosis,PF00225;PF16540;,,,,,,,,,KIF23_HUMAN,Homo sapiens (Human),"actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp139741_c0_seq3,1997,44.5168,0.36280165,6,18,,0,Q9GYZ0,Kinesin-like protein KIF15 (Kinesin-related protein KRP180),Kinesin-like protein KIF15 (Kinesin-related protein KRP180),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005819,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; spindle,PF15908;PF00225;PF12711;,2.00E-67,CHOYP_KI15A.1.1,,,,,,,KIF15_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),microtubule-based movement [GO:0007018] comp139741_c1_seq1,2586,44.6249,0.57386702,692,134,,0,P43304,"Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mtGPD)","Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mtGPD)",GO:0005509; GO:0044255; GO:0006094; GO:0019563; GO:0004368; GO:0009331; GO:0006072; GO:0005743; GO:0044281; GO:0052591,calcium ion binding; cellular lipid metabolic process; gluconeogenesis; glycerol catabolic process; glycerol-3-phosphate dehydrogenase activity; glycerol-3-phosphate dehydrogenase complex; glycerol-3-phosphate metabolic process; mitochondrial inner membrane; small molecule metabolic process; sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity,PF01266;PF16901;PF13499;,0,CHOYP_LOC576660.1.1,,,,,,,GPDM_HUMAN,Homo sapiens (Human),camera-type eye development [GO:0043010]; cellular lipid metabolic process [GO:0044255]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; multicellular organism growth [GO:0035264] comp139743_c0_seq1,889,39.4826,0.3241726,32,104,,8.00E-48,Q99MI9,Protein arginine N-methyltransferase 7 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT7) (EC 2.1.1.125) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) (EC 2.1.1.126),Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7),GO:0043046; GO:0016277; GO:0030154; GO:0005829; GO:0044020; GO:0005634; GO:0035243; GO:0006349; GO:0006355; GO:0000387; GO:0006351,"DNA methylation involved in gamete generation; [myelin basic protein]-arginine N-methyltransferase activity; cell differentiation; cytosol; histone methyltransferase activity (H4-R3 specific); nucleus; protein-arginine omega-N symmetric methyltransferase activity; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; spliceosomal snRNP assembly; transcription, DNA-dependent",,,,,,,,,,ANM7_CRILO,Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster),"cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation [GO:0018216]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]; transcription, DNA-templated [GO:0006351]" comp139746_c0_seq1,2795,37.0662,0.4096196,155,697,,1.00E-32,Q6PR54,Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1),Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1),GO:0007049; GO:0000781; GO:0005737; GO:0001939; GO:0001940; GO:0006974; GO:0005819; GO:0019827; GO:0000723,"cell cycle; chromosome, telomeric region; cytoplasm; female pronucleus; male pronucleus; response to DNA damage stimulus; spindle; stem cell maintenance; telomere maintenance",PF12231;,,,,,,,,,RIF1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; stem cell population maintenance [GO:0019827] comp139748_c1_seq1,939,43.4505,0.36171277,0,0,,3.00E-36,Q7TP65,Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) (Liver regeneration-related protein LRRG057),Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) (Liver regeneration-related protein LRRG057),GO:0051301; GO:0030176; GO:0007067; GO:0007084; GO:0042326; GO:0035307; GO:0051721,cell division; integral to endoplasmic reticulum membrane; mitosis; mitotic nuclear envelope reassembly; negative regulation of phosphorylation; positive regulation of protein dephosphorylation; protein phosphatase 2A binding,PF01693;PF03020;,,,,,,,,,ANKL2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of phosphorylation [GO:0042326]; positive regulation of protein dephosphorylation [GO:0035307] comp139751_c1_seq1,1086,44.8435,0.57007323,0,0,,1.00E-86,P55200,Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],GO:0006306; GO:0071339; GO:0009952; GO:0003682; GO:0035162; GO:0043984; GO:0070577; GO:0042800; GO:0008285; GO:0045944; GO:0051569; GO:0006351; GO:0045322; GO:0008270,"DNA methylation; MLL1 complex; anterior/posterior pattern specification; chromatin binding; embryonic hemopoiesis; histone H4-K16 acetylation; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of histone H3-K4 methylation; transcription, DNA-dependent; unmethylated CpG binding; zinc ion binding",PF05965;PF05964;PF00628;PF00856;PF02008;,9.00E-87,CHOYP_MLL.1.1,,,,,,,MLL1_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; circadian regulation of gene expression [GO:0032922]; cognition [GO:0050890]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of gene expression [GO:0010468]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]" comp139751_c1_seq2,3634,41.1943,0.56952148,167,167,,1.00E-83,Q03164,Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)],GO:0003680; GO:0006306; GO:0071339; GO:0009952; GO:0006915; GO:0003682; GO:0035162; GO:0080182; GO:0043984; GO:0070577; GO:0042800; GO:0008285; GO:2001040; GO:0045944; GO:0032411; GO:0006461; GO:0042803; GO:0051569; GO:0003700; GO:0006366; GO:0044212; GO:0045322; GO:0008270,AT DNA binding; DNA methylation; MLL1 complex; anterior/posterior pattern specification; apoptotic process; chromatin binding; embryonic hemopoiesis; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); negative regulation of cell proliferation; positive regulation of cellular response to drug; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transporter activity; protein complex assembly; protein homodimerization activity; regulation of histone H3-K4 methylation; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; unmethylated CpG binding; zinc ion binding,PF05965;PF05964;PF00628;PF00856;PF02008;,,,,,,,,,MLL1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription from RNA polymerase II promoter [GO:0006366]; visual learning [GO:0008542]" comp139751_c3_seq2,1878,44.6219,0.63450682,29,14,,8.00E-17,O08550,Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7),Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7),GO:0003677; GO:0016458; GO:0080182; GO:0042800; GO:0035097; GO:0009994; GO:0001541; GO:0030728; GO:0051569; GO:0006355; GO:0006351; GO:0008270,"DNA binding; gene silencing; histone H3-K4 trimethylation; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; oocyte differentiation; ovarian follicle development; ovulation; regulation of histone H3-K4 methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;PF02008;,,,,,,,,,MLL4_MOUSE,Mus musculus (Mouse),"gene silencing [GO:0016458]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone lysine methylation [GO:0034968]; memory [GO:0007613]; oocyte differentiation [GO:0009994]; ovarian follicle development [GO:0001541]; ovulation [GO:0030728]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139752_c0_seq1,534,34.6442,0.3141895,24,122,,1.00E-10,Q9WUF2,Early growth response protein 4 (EGR-4),Early growth response protein 4 (EGR-4),GO:0003677; GO:0071320; GO:0071371; GO:0005737; GO:0046872; GO:0043066; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to cAMP; cellular response to gonadotropin stimulus; cytoplasm; metal ion binding; negative regulation of apoptotic process; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,,,,,,,,,EGR4_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139752_c0_seq2,882,33.9002,0.35576194,35,171,,9.00E-27,C9JN71,Zinc finger protein 878,Zinc finger protein 878,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN878_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139752_c0_seq3,514,34.6304,0.39010374,5,21,,3.00E-13,Q8CCE9,Transcription factor E4F1 (EC 6.3.2.-) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F) (Transcription factor phi AP3) (p120E4F),Transcription factor E4F1 (EC 6.3.2.-) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F) (Transcription factor phi AP3) (p120E4F),GO:0003677; GO:0006260; GO:0035497; GO:0051301; GO:0005737; GO:0009790; GO:0016874; GO:0046872; GO:0007067; GO:0000122; GO:0005654; GO:0005634; GO:0016567; GO:0010564; GO:0040008; GO:0009794; GO:0006355; GO:0005819; GO:0006351,"DNA binding; DNA replication; cAMP response element binding; cell division; cytoplasm; embryo development; ligase activity; metal ion binding; mitosis; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; nucleus; protein ubiquitination; regulation of cell cycle process; regulation of growth; regulation of mitotic cell cycle, embryonic; regulation of transcription, DNA-dependent; spindle; transcription, DNA-dependent",PF13912;,,,,,,,,,E4F1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; DNA replication [GO:0006260]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle, embryonic [GO:0009794]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139752_c0_seq4,556,33.0935,0.46510946,30,142,,5.00E-22,P13360,Protein glass,Protein glass,GO:0003677; GO:0003705; GO:0001752; GO:0043153; GO:0046872; GO:0005634; GO:0045944; GO:0010114; GO:0035271; GO:0007605; GO:0007601,DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; compound eye photoreceptor fate commitment; entrainment of circadian clock by photoperiod; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to red light; ring gland development; sensory perception of sound; visual perception,PF00096;,,,,,,,,,GLAS_DROME,Drosophila melanogaster (Fruit fly),"circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp139754_c0_seq1,1940,40.8763,0.53829747,175,640,,3.00E-120,Q5R8H5,General transcription factor IIE subunit 1 (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha),General transcription factor IIE subunit 1 (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha),GO:0046872; GO:0005634; GO:0006355; GO:0043565; GO:0006367,"metal ion binding; nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription initiation from RNA polymerase II promoter",PF08271;PF11521;PF02002;,1.00E-37,CHOYP_T2EA.1.1,,,,,,,T2EA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp139756_c0_seq2,1638,33.6996,0.38736884,126,424,,5.00E-16,Q5BJP5,Transmembrane protein 230,Transmembrane protein 230,GO:0016021,integral to membrane,PF05915;,7.00E-40,CHOYP_RL3.3.7,,,,,,,TM230_RAT,Rattus norvegicus (Rat), comp139757_c0_seq1,1247,41.1387,0.52215988,46,305,,2.00E-119,Q3TX08,"tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)","tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)",GO:0046872; GO:0004809; GO:0000049,metal ion binding; tRNA (guanine-N2-)-methyltransferase activity; tRNA binding,PF02005;PF00642;,8.00E-44,CHOYP_TRMT1.1.1,,,,,,,TRM1_MOUSE,Mus musculus (Mouse),tRNA N2-guanine methylation [GO:0002940] comp139759_c0_seq2,3093,39.8319,0.64092002,64,33,,5.00E-41,Q9HC56,Protocadherin-9,Protocadherin-9,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF08374;,,,,,,,,,PCDH9_HUMAN,Homo sapiens (Human),forebrain development [GO:0030900]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp139760_c1_seq7,1113,31.5364,0.47342307,1015,2936,,1.00E-19,P35244,Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3),Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3),GO:0000730; GO:0005662; GO:0006271; GO:0000082; GO:0005737; GO:0005654; GO:0000718; GO:0006297; GO:0003697; GO:0000722; GO:0032201; GO:0006283,"DNA recombinase assembly; DNA replication factor A complex; DNA strand elongation involved in DNA replication; G1/S transition of mitotic cell cycle; cytoplasm; nucleoplasm; nucleotide-excision repair, DNA damage removal; nucleotide-excision repair, DNA gap filling; single-stranded DNA binding; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair",PF08661;,5.00E-14,CHOYP_LOC100358262.2.3,,,,,,,RFA3_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp139762_c0_seq1,2938,41.627,0.45338451,327,179,,4.00E-94,O95786,Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),GO:0005524; GO:0008026; GO:0039529; GO:0015629; GO:0005829; GO:0009597; GO:0003690; GO:0003725; GO:0045087; GO:0019048; GO:0032480; GO:0002230; GO:0032727; GO:0032728; GO:0051091; GO:0042993; GO:0045944; GO:0030334; GO:0034344; GO:0043330; GO:0032587; GO:0003727; GO:0005923; GO:0008270,ATP binding; ATP-dependent helicase activity; RIG-I signaling pathway; actin cytoskeleton; cytosol; detection of virus; double-stranded DNA binding; double-stranded RNA binding; innate immune response; modulation by virus of host morphology or physiology; negative regulation of type I interferon production; positive regulation of defense response to virus by host; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of cell migration; regulation of type III interferon production; response to exogenous dsRNA; ruffle membrane; single-stranded RNA binding; tight junction; zinc ion binding,PF16739;PF00270;PF00271;PF11648;,4.00E-39,CHOYP_IFIH1.9.14,,,,,,,DDX58_HUMAN,Homo sapiens (Human),cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032] comp139766_c1_seq1,1851,42.4635,0.38380199,38,72,,3.00E-54,B6P4U0,,,,,,4.00E-31,CHOYP_LOC100373584.1.1,,,,,,,TRBP2_BRAFL,, comp139766_c1_seq2,1944,42.3354,0.37917376,101,406,,2.00E-49,B6P4U0,,,,,,,,3.00E-18,ruditapes_c16165,,,,,TRBP2_BRAFL,, comp139766_c1_seq3,2242,35.5932,0.38508894,192,331,,1.00E-151,P58021,Transmembrane 9 superfamily member 2,Transmembrane 9 superfamily member 2,GO:0010008; GO:0016021,endosome membrane; integral to membrane,PF02990;,0,CHOYP_PSMD1.1.1,,,,,,,TM9S2_MOUSE,Mus musculus (Mouse), comp139766_c1_seq4,1227,41.8908,0.50604429,38,75,,2.00E-22,P40071,Transmembrane 9 superfamily member 3,Transmembrane 9 superfamily member 3,GO:0000139; GO:0006878; GO:0016021; GO:0001403; GO:0007124; GO:0007034,Golgi membrane; cellular copper ion homeostasis; integral to membrane; invasive growth in response to glucose limitation; pseudohyphal growth; vacuolar transport,PF02990;,,,,,,,,,TMN3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular copper ion homeostasis [GO:0006878]; invasive growth in response to glucose limitation [GO:0001403]; ion transport [GO:0006811]; pseudohyphal growth [GO:0007124]; vacuolar transport [GO:0007034] comp139766_c1_seq5,649,41.4484,0.36296713,0,9,,,,,,,,,3.00E-15,CHOYP_TM9S4.1.1,,,,,,,,, comp139766_c4_seq2,3362,33.373,0.41770813,324,1553,,,,,,,,,,,3.00E-14,ruditapes_c23267,,,,,,, comp139767_c2_seq6,780,35,0.84661386,0,36,,3.00E-51,Q80Y14,"Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5)","Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5)",GO:0051537; GO:0045454; GO:0009055; GO:0030097; GO:0046872; GO:0005739; GO:0005634; GO:0015035,"2 iron, 2 sulfur cluster binding; cell redox homeostasis; electron carrier activity; hemopoiesis; metal ion binding; mitochondrion; nucleus; protein disulfide oxidoreductase activity",PF00462;,3.00E-46,CHOYP_BRAFLDRAFT_129234.1.1,4.00E-50,ruditapes2_c2962,,,,,GLRX5_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; hemopoiesis [GO:0030097] comp139770_c0_seq2,757,40.4227,0.48579448,61,8,,1.00E-24,Q8BMD2,Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog),Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog),GO:0030154; GO:0005814; GO:0042384; GO:0036064; GO:0046872; GO:0007275; GO:0005634; GO:0007283,cell differentiation; centriole; cilium assembly; cilium basal body; metal ion binding; multicellular organismal development; nucleus; spermatogenesis,PF13815;,3.00E-65,CHOYP_LOC100375191.1.2,,,,,,,DZIP1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cilium assembly [GO:0042384]; cytoplasmic sequestering of protein [GO:0051220]; establishment of protein localization [GO:0045184]; multicellular organism development [GO:0007275]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283] comp139771_c0_seq1,2219,37.0437,1.01977649,185,818,,2.00E-49,Q6NXR0,Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1),Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1),GO:0005525; GO:0016817; GO:0016020,"GTP binding; hydrolase activity, acting on acid anhydrides; membrane",PF05049;,,,,,,,,,IIGP5_HUMAN,Homo sapiens (Human), comp139776_c0_seq1,2731,38.301,0.45065988,56,195,,2.00E-179,Q6AY53,Deoxyhypusine synthase (DHS) (EC 2.5.1.46),Deoxyhypusine synthase (DHS) (EC 2.5.1.46),GO:0050983; GO:0034038; GO:0008612; GO:0051289,deoxyhypusine biosynthetic process from spermidine; deoxyhypusine synthase activity; peptidyl-lysine modification to hypusine; protein homotetramerization,PF01916;,,,,,2.00E-94,AM858464.p.cg.6,3,,DHYS_RAT,Rattus norvegicus (Rat),deoxyhypusine biosynthetic process from spermidine [GO:0050983]; glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; protein homotetramerization [GO:0051289] comp139776_c0_seq2,2433,38.2244,0.41712644,0,0,,5.00E-178,Q6AY53,Deoxyhypusine synthase (DHS) (EC 2.5.1.46),Deoxyhypusine synthase (DHS) (EC 2.5.1.46),GO:0050983; GO:0034038; GO:0008612; GO:0051289,deoxyhypusine biosynthetic process from spermidine; deoxyhypusine synthase activity; peptidyl-lysine modification to hypusine; protein homotetramerization,PF01916;,6.00E-150,CHOYP_DHPS.1.1,,,,,,,DHYS_RAT,Rattus norvegicus (Rat),deoxyhypusine biosynthetic process from spermidine [GO:0050983]; glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; protein homotetramerization [GO:0051289] comp139779_c0_seq1,1600,43,0.96351807,82,1047,,8.00E-58,P34080,Aquaporin-2 (AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct),Aquaporin-2 (AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct),GO:0005794; GO:0003779; GO:0030042; GO:0007568; GO:0016324; GO:0006915; GO:0016323; GO:0006884; GO:0071280; GO:0071288; GO:0042631; GO:0030136; GO:0030659; GO:0005769; GO:0070382; GO:0007565; GO:0015168; GO:0006972; GO:0016021; GO:0005764; GO:0072205; GO:0051928; GO:0043234; GO:0055037; GO:0003097; GO:0051592; GO:0033762; GO:0032496; GO:0010226; GO:0009651; GO:0042594; GO:0005791; GO:0005802; GO:0015250; GO:0030104,Golgi apparatus; actin binding; actin filament depolymerization; aging; apical plasma membrane; apoptotic process; basolateral plasma membrane; cell volume homeostasis; cellular response to copper ion; cellular response to mercury ion; cellular response to water deprivation; clathrin-coated vesicle; cytoplasmic vesicle membrane; early endosome; exocytic vesicle; female pregnancy; glycerol transmembrane transporter activity; hyperosmotic response; integral to membrane; lysosome; metanephric collecting duct development; positive regulation of calcium ion transport; protein complex; recycling endosome; renal water transport; response to calcium ion; response to glucagon stimulus; response to lipopolysaccharide; response to lithium ion; response to salt stress; response to starvation; rough endoplasmic reticulum; trans-Golgi network; water channel activity; water homeostasis,PF00230;,,,,,,,,,AQP2_RAT,Rattus norvegicus (Rat),actin filament depolymerization [GO:0030042]; aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to water deprivation [GO:0042631]; cellular water homeostasis [GO:0009992]; cell volume homeostasis [GO:0006884]; female pregnancy [GO:0007565]; hyperosmotic response [GO:0006972]; ion transmembrane transport [GO:0034220]; positive regulation of calcium ion transport [GO:0051928]; response to calcium ion [GO:0051592]; response to glucagon [GO:0033762]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to salt stress [GO:0009651]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]; water homeostasis [GO:0030104]; water transport [GO:0006833] comp139786_c0_seq1,1836,40.2505,0.27755542,301,1417,,8.00E-59,Q7PYU6,Zinc finger CCCH-type with G patch domain-containing protein,Zinc finger CCCH-type with G patch domain-containing protein,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01585;,,,,,,,,,ZGPAT_ANOGA,Anopheles gambiae (African malaria mosquito),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139786_c0_seq2,746,37.6676,0.31875457,23,242,,2.00E-23,Q7PYU6,Zinc finger CCCH-type with G patch domain-containing protein,Zinc finger CCCH-type with G patch domain-containing protein,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01585;,,,,,,,,,ZGPAT_ANOGA,Anopheles gambiae (African malaria mosquito),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139790_c0_seq1,1106,36.0759,0.36858446,156,409,,4.00E-19,Q28GD9,Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B),Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B),GO:0006401; GO:0005634; GO:0032299,RNA catabolic process; nucleus; ribonuclease H2 complex,PF09468;,,,,,,,,,RNH2B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),RNA catabolic process [GO:0006401] comp139791_c0_seq1,3105,42.2222,0.35091918,13,107,,0,Q7ZX96,Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (An4a) (Nucleoporin Nup93),Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (An4a) (Nucleoporin Nup93),GO:0051028; GO:0031965; GO:0034399; GO:0005643; GO:0051292; GO:0015031; GO:0017056,mRNA transport; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore complex assembly; protein transport; structural constituent of nuclear pore,PF04097;,0,CHOYP_BRAFLDRAFT_275527.1.1,,,,,,,NUP93_XENLA,Xenopus laevis (African clawed frog),mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031] comp139791_c0_seq2,3102,42.1663,0.35960563,64,481,,3.00E-50,P34077,Nucleoporin NIC96 (96 kDa nucleoporin-interacting component) (Nuclear pore protein NIC96),Nucleoporin NIC96 (96 kDa nucleoporin-interacting component) (Nuclear pore protein NIC96),GO:0051028; GO:0031965; GO:0044612; GO:0044615; GO:0006999; GO:0006606; GO:0000055; GO:0017056,mRNA transport; nuclear membrane; nuclear pore linkers; nuclear pore nuclear basket; nuclear pore organization; protein import into nucleus; ribosomal large subunit export from nucleus; structural constituent of nuclear pore,PF04097;,0,CHOYP_BRAFLDRAFT_275527.1.1,,,,,,,NIC96_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055] comp139791_c0_seq3,3132,42.1137,0.36409237,167,689,,0,Q7ZX96,Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (An4a) (Nucleoporin Nup93),Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (An4a) (Nucleoporin Nup93),GO:0051028; GO:0031965; GO:0034399; GO:0005643; GO:0051292; GO:0015031; GO:0017056,mRNA transport; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore complex assembly; protein transport; structural constituent of nuclear pore,PF04097;,,,,,,,,,NUP93_XENLA,Xenopus laevis (African clawed frog),mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031] comp139794_c0_seq1,1411,41.3182,0.65262269,124,619,,3.00E-47,P92204,Negative elongation factor E,Negative elongation factor E,GO:0032021; GO:0005694; GO:0003729; GO:0034244; GO:0007070; GO:0022008; GO:0000166; GO:0045944; GO:0006368; GO:0017053,NELF complex; chromosome; mRNA binding; negative regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter during mitosis; neurogenesis; nucleotide binding; positive regulation of transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; transcriptional repressor complex,PF00076;,1.00E-36,CHOYP_PHUM_PHUM616130.1.1,4.00E-71,ruditapes_c26479,,,,,NELFE_DROME,Drosophila melanogaster (Fruit fly),"negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp139798_c0_seq2,1940,41.4948,0.53255692,0,0,,0,Q6PFM0,Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr),Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr),GO:0008380; GO:0030154; GO:0033746; GO:0033749; GO:0006397; GO:0046872; GO:0005730; GO:0005654; GO:0070815; GO:0018395; GO:0006909; GO:0048024; GO:0006355; GO:0003727; GO:0002040; GO:0006351,"RNA splicing; cell differentiation; histone demethylase activity (H3-R2 specific); histone demethylase activity (H4-R3 specific); mRNA processing; metal ion binding; nucleolus; nucleoplasm; peptidyl-lysine 5-dioxygenase activity; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; phagocytosis; regulation of mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; single-stranded RNA binding; sprouting angiogenesis; transcription, DNA-dependent",PF02373;,6.00E-118,CHOYP_LOC100370709.1.1,,,,,,,JMJD6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp139798_c0_seq3,1907,41.6361,0.50093184,9,1,,0,Q6PFM0,Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr),Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr),GO:0008380; GO:0030154; GO:0033746; GO:0033749; GO:0006397; GO:0046872; GO:0005730; GO:0005654; GO:0070815; GO:0018395; GO:0006909; GO:0048024; GO:0006355; GO:0003727; GO:0002040; GO:0006351,"RNA splicing; cell differentiation; histone demethylase activity (H3-R2 specific); histone demethylase activity (H4-R3 specific); mRNA processing; metal ion binding; nucleolus; nucleoplasm; peptidyl-lysine 5-dioxygenase activity; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; phagocytosis; regulation of mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; single-stranded RNA binding; sprouting angiogenesis; transcription, DNA-dependent",PF02373;,,,,,,,,,JMJD6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp139798_c0_seq4,1951,41.5172,0.54107342,9,0,,6.00E-48,Q9M9E8,F-box protein At1g78280,F-box protein At1g78280,GO:0005829; GO:0016772,"cytosol; transferase activity, transferring phosphorus-containing groups",PF01636;PF00646;,,,,,,,,,FB92_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp139798_c0_seq7,1918,41.5537,0.50012091,0,0,,2.00E-19,Q8BFT6,JmjC domain-containing protein 4 (Jumonji domain-containing protein 4),JmjC domain-containing protein 4 (Jumonji domain-containing protein 4),,,,2.00E-123,CHOYP_LOC100370709.1.1,,,,,,,JMJD4_MOUSE,Mus musculus (Mouse), comp139798_c0_seq9,1940,41.4948,0.52019385,0,0,,1.00E-99,Q5R6G2,Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR),Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR),GO:0008380; GO:0030154; GO:0033746; GO:0033749; GO:0006397; GO:0046872; GO:0005730; GO:0005654; GO:0070815; GO:0018395; GO:0048024; GO:0006355; GO:0003727; GO:0002040; GO:0006351,"RNA splicing; cell differentiation; histone demethylase activity (H3-R2 specific); histone demethylase activity (H4-R3 specific); mRNA processing; metal ion binding; nucleolus; nucleoplasm; peptidyl-lysine 5-dioxygenase activity; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; regulation of mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; single-stranded RNA binding; sprouting angiogenesis; transcription, DNA-dependent",PF02373;,3.00E-103,CHOYP_LOC100370709.1.1,,,,,,,JMJD6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp139804_c0_seq3,884,36.1991,0.87662064,10,30,,,,,,,,,,,6.00E-16,ruditapes_c19132,,,,,,, comp139804_c1_seq1,499,39.2786,0.88542022,25,32,,6.00E-12,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp139805_c0_seq1,1587,40.3277,0.68799444,11,870,,5.00E-93,Q29496,Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24),Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,,,,,,,,,CP3AO_SHEEP,Ovis aries (Sheep), comp139807_c0_seq1,2201,35.393,0.47994779,3554,10181,,6.00E-18,Q9CQX4,PCNA-associated factor (HCV NS5A-transactivated protein 9 homolog) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF),PCNA-associated factor (HCV NS5A-transactivated protein 9 homolog) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF),GO:0006260; GO:0051297; GO:0003682; GO:0005634; GO:0048471; GO:0051726; GO:0009411; GO:0019985,DNA replication; centrosome organization; chromatin binding; nucleus; perinuclear region of cytoplasm; regulation of cell cycle; response to UV; translesion synthesis,PF15715;,,,,,,,,,PAF_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; centrosome organization [GO:0051297]; DNA replication [GO:0006260]; regulation of cell cycle [GO:0051726]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp139808_c0_seq1,3136,42.8571,0.7076362,8,18,,0,Q96PQ7,Kelch-like protein 5,Kelch-like protein 5,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF07707;PF00651;PF01344;,0,CHOYP_KLHL5.1.1,,,,,,,KLHL5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp139808_c0_seq2,1397,39.8712,0.71265035,0,0,,3.00E-07,Q5VTJ3,Kelch domain-containing protein 7A,Kelch domain-containing protein 7A,GO:0016021,integral to membrane,PF01344;,,,,,,,,,KLD7A_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp139808_c0_seq3,3474,43.3506,0.66766416,25,3,,0,Q96PQ7,Kelch-like protein 5,Kelch-like protein 5,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF07707;PF00651;PF01344;,0,CHOYP_KLHL5.1.1,,,,,,,KLHL5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp139808_c0_seq4,2455,41.9552,0.66450227,18,0,,4.00E-48,Q920Q8,Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog) (Kelch family protein Nd1-L) (ND1-L2) (Nd1-S),Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog) (Kelch family protein Nd1-L) (ND1-L2) (Nd1-S),GO:0005737; GO:0005856; GO:2001243; GO:0005634,cytoplasm; cytoskeleton; negative regulation of intrinsic apoptotic signaling pathway; nucleus,PF07707;PF00651;PF01344;,1.00E-14,CHOYP_KLH20.2.2,,,,,,,NS1BP_MOUSE,Mus musculus (Mouse),negative regulation of intrinsic apoptotic signaling pathway [GO:2001243] comp139810_c0_seq1,1216,43.8322,0.62739188,1469,10502,,2.00E-37,P77735,Uncharacterized oxidoreductase YajO (EC 1.-.-.-),Uncharacterized oxidoreductase YajO (EC 1.-.-.-),GO:0016491; GO:0006772,oxidoreductase activity; thiamine metabolic process,PF00248;,7.00E-51,CHOYP_LOC100366708.1.1,6.00E-75,ruditapes_c28967,,,,,YAJO_ECOLI,Escherichia coli (strain K12),thiamine metabolic process [GO:0006772] comp139811_c1_seq1,368,53.8043,0.72428221,257,2567,,2.00E-19,Q8N2A0,Putative uncharacterized protein encoded by LINC00269,Putative uncharacterized protein encoded by LINC00269,,,,2.00E-19,CHOYP_RN7SL2.1.1,,,,,,,CX062_HUMAN,Homo sapiens (Human), comp139813_c0_seq3,2283,41.7433,0.45549232,0,0,,7.00E-118,Q0VDN7,RUN domain-containing protein 1,RUN domain-containing protein 1,,,PF02759;,2.00E-163,CHOYP_BRAFLDRAFT_279949.1.1,,,,,,,RUND1_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp139814_c0_seq1,2080,34.7596,0.56013148,7,18,,,,,,,,,8.00E-47,CHOYP_NR1AA.1.1,,,,,,,,, comp139814_c0_seq2,2096,34.5897,0.5613128,3,24,,9.00E-39,Q52KD8,Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog),Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog),GO:0070776; GO:0035267; GO:0043968; GO:0044154; GO:0043983; GO:0043981; GO:0043982; GO:0005730; GO:0006355; GO:0006351,"MOZ/MORF histone acetyltransferase complex; NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H3-K14 acetylation; histone H4-K12 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09340;,9.00E-46,CHOYP_AGAP_AGAP006810.1.2,,,,,,,EAF6_XENLA,Xenopus laevis (African clawed frog),"histone H2A acetylation [GO:0043968]; histone H3-K14 acetylation [GO:0044154]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139816_c0_seq1,1966,39.3693,0.41049801,54,310,,6.00E-25,P0CR48,Protein CSN12 homolog,Protein CSN12 homolog,,,PF01399;,5.00E-144,CHOYP_PCID2.1.1,,,,,,,CSN12_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans), comp139816_c0_seq2,1938,38.9061,0.39907323,35,141,,1.00E-66,Q9VTL1,PCI domain-containing protein 2 homolog (dmPCID2) (CSN12-like protein),PCI domain-containing protein 2 homolog (dmPCID2) (CSN12-like protein),GO:0005737; GO:0006406; GO:0005634; GO:0005844; GO:0006417,cytoplasm; mRNA export from nucleus; nucleus; polysome; regulation of translation,PF01399;,,,,,,,,,PCID2_DROME,Drosophila melanogaster (Fruit fly),mRNA export from nucleus [GO:0006406]; regulation of translation [GO:0006417] comp139816_c0_seq3,1818,39.549,0.38241672,27,142,,4.00E-115,Q8BFV2,PCI domain-containing protein 2 (CSN12-like protein),PCI domain-containing protein 2 (CSN12-like protein),GO:0043066; GO:0045579; GO:0090267; GO:0045893; GO:0043488; GO:0048536,"negative regulation of apoptotic process; positive regulation of B cell differentiation; positive regulation of mitotic cell cycle spindle assembly checkpoint; positive regulation of transcription, DNA-dependent; regulation of mRNA stability; spleen development",PF01399;,,,,,,,,,PCID2_MOUSE,Mus musculus (Mouse),"negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mRNA stability [GO:0043488]; spleen development [GO:0048536]" comp139818_c0_seq1,1218,38.0952,0.32835039,153,892,,3.00E-109,Q0P5A2,"2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5)","2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5)",GO:0008168; GO:0005739; GO:0006744,methyltransferase activity; mitochondrion; ubiquinone biosynthetic process,PF01209;,2.00E-50,CHOYP_COQ5.1.1,,,,,,,COQ5_BOVIN,Bos taurus (Bovine),methylation [GO:0032259]; ubiquinone biosynthetic process [GO:0006744] comp139820_c1_seq11,3864,45.8592,0.32359888,16,9,,0,Q6PDG5,SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2),SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2),GO:0003677; GO:0016514; GO:0003682; GO:0006338; GO:0071565; GO:0045892; GO:0007399; GO:0071564; GO:0006337; GO:0045893; GO:0006351; GO:0017053,"DNA binding; SWI/SNF complex; chromatin binding; chromatin remodeling; nBAF complex; negative regulation of transcription, DNA-dependent; nervous system development; npBAF complex; nucleosome disassembly; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; transcriptional repressor complex",PF00249;PF04433;PF16495;PF16496;PF16498;,0,CHOYP_SMRC2.2.2,,,,,,,SMRC2_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome disassembly [GO:0006337]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment [GO:0021882]; transcription, DNA-templated [GO:0006351]" comp139820_c1_seq4,3897,45.8045,0.32687633,25,23,,0,Q6PDG5,SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2),SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2),GO:0003677; GO:0016514; GO:0003682; GO:0006338; GO:0071565; GO:0045892; GO:0007399; GO:0071564; GO:0006337; GO:0045893; GO:0006351; GO:0017053,"DNA binding; SWI/SNF complex; chromatin binding; chromatin remodeling; nBAF complex; negative regulation of transcription, DNA-dependent; nervous system development; npBAF complex; nucleosome disassembly; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; transcriptional repressor complex",PF00249;PF04433;PF16495;PF16496;PF16498;,0,CHOYP_SMRC2.2.2,1.00E-109,ruditapes_c15628,,,,,SMRC2_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome disassembly [GO:0006337]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment [GO:0021882]; transcription, DNA-templated [GO:0006351]" comp139823_c0_seq1,2564,33.8144,0.5241958,753,10154,,1.00E-33,Q11004,40 kDa peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin-40) (CYP-40) (Rotamase),40 kDa peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin-40) (CYP-40) (Rotamase),GO:0005829; GO:0005634; GO:0042277; GO:0003755; GO:0043234; GO:0006457; GO:0000413; GO:0007088; GO:0006950,cytosol; nucleus; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein complex; protein folding; protein peptidyl-prolyl isomerization; regulation of mitosis; response to stress,PF00160;,,,,,,,,,PPID_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein folding [GO:0006457] comp139823_c0_seq2,2444,33.7971,0.47751371,1119,9622,,6.00E-76,P24368,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP),GO:0005788; GO:0042470; GO:0051169; GO:0042277; GO:0003755; GO:0006457; GO:0000413; GO:0005790,endoplasmic reticulum lumen; melanosome; nuclear transport; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; smooth endoplasmic reticulum,PF00160;,2.00E-68,CHOYP_DVIR_GJ21252.1.1,7.00E-84,ruditapes_lrc15083,,,,,PPIB_RAT,Rattus norvegicus (Rat),bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; nuclear transport [GO:0051169]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] comp139827_c0_seq1,1320,42.7273,0.54192819,41,73,,0,P97789,5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog),5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog),GO:0004534; GO:0003677; GO:0003723; GO:0006396; GO:0007569; GO:0000932; GO:0071044; GO:0007126; GO:0000723,5'-3' exoribonuclease activity; DNA binding; RNA binding; RNA processing; cell aging; cytoplasmic mRNA processing body; histone mRNA catabolic process; meiosis; telomere maintenance,PF03159;,0,CHOYP_LOC100369596.1.1,,,,,,,XRN1_MOUSE,Mus musculus (Mouse),cell aging [GO:0007569]; histone mRNA catabolic process [GO:0071044]; meiotic nuclear division [GO:0007126]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; telomere maintenance [GO:0000723] comp139827_c0_seq3,860,43.1395,0.43640488,0,0,,,,,,,,,2.00E-100,CHOYP_LOC100369596.1.1,,,,,,,,, comp139827_c0_seq5,609,44.4992,0.43624279,41,9,,1.00E-64,P97789,5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog),5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog),GO:0004534; GO:0003677; GO:0003723; GO:0006396; GO:0007569; GO:0000932; GO:0071044; GO:0007126; GO:0000723,5'-3' exoribonuclease activity; DNA binding; RNA binding; RNA processing; cell aging; cytoplasmic mRNA processing body; histone mRNA catabolic process; meiosis; telomere maintenance,PF03159;,,,,,,,,,XRN1_MOUSE,Mus musculus (Mouse),cell aging [GO:0007569]; histone mRNA catabolic process [GO:0071044]; meiotic nuclear division [GO:0007126]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; telomere maintenance [GO:0000723] comp139829_c0_seq2,1465,32.2184,0.39767814,316,578,,2.00E-09,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp139832_c0_seq1,1563,36.4683,0.98113058,72,449,,5.00E-24,Q8BLI0,ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1),GO:0008237; GO:0005578; GO:0008270,metallopeptidase activity; proteinaceous extracellular matrix; zinc ion binding,PF07679;PF08686;PF00090;,,,,,,,,,ATL1_MOUSE,Mus musculus (Mouse), comp139838_c2_seq1,1006,39.7614,0.73906393,0,18,,1.00E-98,Q7SXV9,Calumenin-B,Calumenin-B,GO:0005509; GO:0005576; GO:0042470; GO:0033018,calcium ion binding; extracellular region; melanosome; sarcoplasmic reticulum lumen,PF13202;,2.00E-25,CHOYP_CALUB.1.2,,,,,,,CALUB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139838_c2_seq3,1555,40.4502,0.67681629,8,23,,7.00E-120,Q7SXV9,Calumenin-B,Calumenin-B,GO:0005509; GO:0005576; GO:0042470; GO:0033018,calcium ion binding; extracellular region; melanosome; sarcoplasmic reticulum lumen,PF13202;,8.00E-77,CHOYP_CALUB.2.2,,,,,,,CALUB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139838_c2_seq4,1579,40.6586,0.66137144,2,6,,1.00E-07,Q4R585,45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4),45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4),GO:0005796; GO:0005509,Golgi lumen; calcium ion binding,PF13202;PF13499;,,,,,,,,,CAB45_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp139846_c0_seq1,2103,38.6115,0.55167548,173,317,,3.00E-48,Q28GD4,ELAV-like protein 2 (Protein ElrB),ELAV-like protein 2 (Protein ElrB),GO:0003723; GO:0005938; GO:0007275; GO:0000166; GO:0030529,RNA binding; cell cortex; multicellular organismal development; nucleotide binding; ribonucleoprotein complex,PF00076;,,,,,,,,,ELAV2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),multicellular organism development [GO:0007275] comp139846_c0_seq2,475,40.2105,0.60184175,0,0,,8.00E-12,Q9UT83,Meiotically up-regulated gene 28 protein,Meiotically up-regulated gene 28 protein,GO:0003723; GO:0005619; GO:0031321; GO:0005737; GO:0007126; GO:0000166; GO:0005628,RNA binding; ascospore wall; ascospore-type prospore assembly; cytoplasm; meiosis; nucleotide binding; prospore membrane,PF00076;,,,,,,,,,MUG28_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),meiotic cell cycle [GO:0051321]; sporulation resulting in formation of a cellular spore [GO:0030435] comp139850_c0_seq1,254,42.5197,0.82112185,7,5,,,,,,,,,,,2.00E-16,ruditapes2_c960,,,,,,, comp139850_c0_seq4,1569,45.7616,0.38047232,67,86,,6.00E-161,O88813,Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5),Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5),GO:0005524; GO:0032869; GO:0005789; GO:0015908; GO:0016021; GO:0004467; GO:0005741; GO:0005739; GO:0008654; GO:0032000; GO:0010747; GO:0010867; GO:0070723; GO:0009749; GO:0007584; GO:0009744,ATP binding; cellular response to insulin stimulus; endoplasmic reticulum membrane; fatty acid transport; integral to membrane; long-chain fatty acid-CoA ligase activity; mitochondrial outer membrane; mitochondrion; phospholipid biosynthetic process; positive regulation of fatty acid beta-oxidation; positive regulation of plasma membrane long-chain fatty acid transport; positive regulation of triglyceride biosynthetic process; response to cholesterol; response to glucose stimulus; response to nutrient; response to sucrose stimulus,PF00501;,8.00E-39,CHOYP_BRAFLDRAFT_120586.1.1,,,,,,,ACSL5_RAT,Rattus norvegicus (Rat),cellular response to insulin stimulus [GO:0032869]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; phospholipid biosynthetic process [GO:0008654]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of plasma membrane long-chain fatty acid transport [GO:0010747]; positive regulation of triglyceride biosynthetic process [GO:0010867]; response to cholesterol [GO:0070723]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to sucrose [GO:0009744] comp139850_c0_seq6,1128,44.0603,0.29366651,0,0,,7.00E-08,P86832,4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33),4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33),GO:0018861; GO:0005524,4-chlorobenzoate-CoA ligase activity; ATP binding,PF00501;PF13193;,,,,,,,,,CBCL2_ARTSP,Arthrobacter sp.,metabolic process [GO:0008152] comp139852_c1_seq1,1998,38.6386,0.52601017,146,428,,2.00E-115,Q9Y5B6,PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1),PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1),GO:0003677; GO:0005829; GO:0007517; GO:0005634; GO:0031062; GO:2000288; GO:0045944; GO:0014842; GO:0006355; GO:0003700; GO:0006351,"DNA binding; cytosol; muscle organ development; nucleus; positive regulation of histone methylation; positive regulation of myoblast proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of satellite cell proliferation; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF07842;,8.00E-34,CHOYP_PAXB1.1.2,9.00E-50,ruditapes_c26142,,,,,GCFC1_HUMAN,Homo sapiens (Human),"muscle organ development [GO:0007517]; positive regulation of histone methylation [GO:0031062]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription, DNA-templated [GO:0006351]" comp139854_c1_seq1,3343,32.0969,0.67524516,4,324,,,,,,,,,8.00E-11,CHOYP_SELM.2.3,,,,,,,,, comp139854_c1_seq2,3357,32.0226,0.67522298,1,66,,3.00E-11,Q6GP98,Selenoprotein M (SelM),Selenoprotein M (SelM),GO:0005783,endoplasmic reticulum,PF08806;,2.00E-12,CHOYP_LOC590298.3.3,,,,,,,SELM_XENLA,Xenopus laevis (African clawed frog), comp139854_c1_seq3,3355,32.1311,0.6831376,0,10,,1.00E-19,G4WAW9,Selenoprotein M,Selenoprotein M,GO:0005783,endoplasmic reticulum,PF08806;,8.00E-11,CHOYP_SELM.2.3,,,,,,,SELM_ERISI,Eriocheir sinensis (Chinese mitten crab), comp139854_c1_seq4,3369,32.1164,0.68067995,0,0,,1.00E-19,G4WAW9,Selenoprotein M,Selenoprotein M,GO:0005783,endoplasmic reticulum,PF08806;,2.00E-12,CHOYP_LOC590298.3.3,,,,,,,SELM_ERISI,Eriocheir sinensis (Chinese mitten crab), comp139855_c0_seq1,3576,42.4776,0.9283886,37,49465,female>male,3.00E-20,Q20930,ADAM family mig-17 (EC 3.4.24.-) (A disintegrin and metalloproteinase mig-17) (Abnormal cell migration protein 17),ADAM family mig-17 (EC 3.4.24.-) (A disintegrin and metalloproteinase mig-17) (Abnormal cell migration protein 17),GO:0005604; GO:0005615; GO:0035262; GO:0046872; GO:0004222; GO:0006508; GO:0030334,basement membrane; extracellular space; gonad morphogenesis; metal ion binding; metalloendopeptidase activity; proteolysis; regulation of cell migration,PF01421;,,,,,,,,,MIG17_CAEEL,Caenorhabditis elegans,gonad morphogenesis [GO:0035262]; regulation of cell migration [GO:0030334] comp139861_c0_seq1,1265,41.0277,0.41619871,0,0,,5.00E-08,Q7T6Y2,Putative serine/threonine-protein kinase/receptor R831 (EC 2.7.11.1),Putative serine/threonine-protein kinase/receptor R831 (EC 2.7.11.1),GO:0005524; GO:0009190; GO:0016021; GO:0035556; GO:0016849; GO:0004674,ATP binding; cyclic nucleotide biosynthetic process; integral to membrane; intracellular signal transduction; phosphorus-oxygen lyase activity; protein serine/threonine kinase activity,PF00211;PF12849;PF07714;,,,,,,,,,YR831_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),cyclic nucleotide biosynthetic process [GO:0009190]; intracellular signal transduction [GO:0035556] comp139861_c0_seq2,1175,41.3617,0.44113316,0,0,,1.00E-12,Q9Z2A6,Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7),Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7),GO:0005524; GO:0004707; GO:0008156; GO:0000122; GO:0005634; GO:0045732; GO:0001934; GO:0031398; GO:0046777; GO:0032355,ATP binding; MAP kinase activity; negative regulation of DNA replication; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of protein catabolic process; positive regulation of protein phosphorylation; positive regulation of protein ubiquitination; protein autophosphorylation; response to estradiol stimulus,PF00069;,,,,,,,,,MK15_RAT,Rattus norvegicus (Rat),negative regulation of DNA replication [GO:0008156]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to estradiol [GO:0032355] comp139861_c0_seq3,2724,43.8326,0.40529548,0,0,,5.00E-64,Q55G97,TBC domain-containing protein kinase-like protein (RabGAP/TBC domain-containing protein),TBC domain-containing protein kinase-like protein (RabGAP/TBC domain-containing protein),GO:0005524; GO:0005097; GO:0032851; GO:0004672,ATP binding; Rab GTPase activator activity; positive regulation of Rab GTPase activity; protein kinase activity,PF00069;PF00566;PF00581;,0,CHOYP_BRAFLDRAFT_113518.1.1,,,,,,,TBCK_DICDI,Dictyostelium discoideum (Slime mold), comp139861_c0_seq5,2814,43.6034,0.39645153,0,0,,0,Q5F361,TBC domain-containing protein kinase-like protein,TBC domain-containing protein kinase-like protein,GO:0005097; GO:0032851; GO:0016772,"Rab GTPase activator activity; positive regulation of Rab GTPase activity; transferase activity, transferring phosphorus-containing groups",PF00069;PF00566;PF00581;,,,,,,,,,TBCK_CHICK,Gallus gallus (Chicken),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp139861_c0_seq6,2723,43.7385,0.39190048,0,0,,5.00E-20,Q8T2I8,Serine/threonine-protein kinase sepA (EC 2.7.11.1) (Septase A),Serine/threonine-protein kinase sepA (EC 2.7.11.1) (Septase A),GO:0005524; GO:0007049; GO:0051301; GO:0005737; GO:0005815; GO:0004674,ATP binding; cell cycle; cell division; cytoplasm; microtubule organizing center; protein serine/threonine kinase activity,PF00069;,,,,,,,,,SEPA_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cleavage furrow formation [GO:0036089]; mitotic cytokinesis [GO:0000281]; sorocarp development [GO:0030587] comp139861_c0_seq7,2633,43.9803,0.40085348,0,0,,0,Q5F361,TBC domain-containing protein kinase-like protein,TBC domain-containing protein kinase-like protein,GO:0005097; GO:0032851; GO:0016772,"Rab GTPase activator activity; positive regulation of Rab GTPase activity; transferase activity, transferring phosphorus-containing groups",PF00069;PF00566;PF00581;,0,CHOYP_BRAFLDRAFT_113518.1.1,,,,,,,TBCK_CHICK,Gallus gallus (Chicken),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp139862_c0_seq1,1105,35.5656,0.63272363,228,1145,,3.00E-19,Q5R4R9,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa homolog) (Protein HRPAP20),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa homolog) (Protein HRPAP20),GO:0032981; GO:0005739,mitochondrial respiratory chain complex I assembly; mitochondrion,PF06784;,,,,,,,,,NDUF4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mitochondrial respiratory chain complex I assembly [GO:0032981] comp139864_c0_seq1,207,42.5121,0.54423039,0,3,,9.00E-18,Q90744,Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B),Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B),GO:0008456; GO:0005975; GO:0005764,alpha-N-acetylgalactosaminidase activity; carbohydrate metabolic process; lysosome,PF16499;,,,,,,,,,NAGAB_CHICK,Gallus gallus (Chicken),carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139] comp139864_c2_seq1,1670,37.7844,0.65086124,331,2338,,2.00E-72,Q5C9L6,(S)-coclaurine N-methyltransferase (TfCNMT) (EC 2.1.1.140),(S)-coclaurine N-methyltransferase (TfCNMT) (EC 2.1.1.140),GO:0030794; GO:0005737; GO:0008610,(S)-coclaurine-N-methyltransferase activity; cytoplasm; lipid biosynthetic process,PF02353;,4.00E-100,CHOYP_NEMVEDRAFT_V1G237881.1.1,,,,,,,CNMT_THLFG,Thalictrum flavum subsp. glaucum (Yellow meadow rue), comp139864_c2_seq2,1154,38.7348,0.46598921,23,247,,3.00E-44,P51569,Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),GO:0005794; GO:0004557; GO:0005576; GO:0016139; GO:0046477; GO:0005764; GO:0045019; GO:0051001; GO:0009311; GO:0042803; GO:0052692; GO:0005102,Golgi apparatus; alpha-galactosidase activity; extracellular region; glycoside catabolic process; glycosylceramide catabolic process; lysosome; negative regulation of nitric oxide biosynthetic process; negative regulation of nitric-oxide synthase activity; oligosaccharide metabolic process; protein homodimerization activity; raffinose alpha-galactosidase activity; receptor binding,PF16499;,5.00E-21,CHOYP_LOC663249.1.1,,,,,,,AGAL_MOUSE,Mus musculus (Mouse),glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] comp139864_c2_seq5,1122,44.2068,0.25804248,22,227,,3.00E-136,Q9UJ83,2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2),2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2),GO:0016830; GO:0001561; GO:0000287; GO:0005782; GO:0051259; GO:0030976,carbon-carbon lyase activity; fatty acid alpha-oxidation; magnesium ion binding; peroxisomal matrix; protein oligomerization; thiamine pyrophosphate binding,PF02775;PF00205;PF02776;,2.00E-50,CHOYP_HACL1.1.1,,,,,,,HACL1_HUMAN,Homo sapiens (Human),fatty acid alpha-oxidation [GO:0001561]; protein oligomerization [GO:0051259] comp139867_c0_seq5,448,40.4018,1.06905295,31,38,,3.00E-06,Q2TBI2,THAP domain-containing protein 4,THAP domain-containing protein 4,GO:0003677; GO:0046872,DNA binding; metal ion binding,PF08768;PF05485;,,,,,,,,,THAP4_BOVIN,Bos taurus (Bovine), comp139869_c0_seq1,1063,43.7441,0.59056481,38,143,,9.00E-167,Q9WVA3,Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5),Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5),GO:0008608; GO:0051301; GO:0000777; GO:0007126; GO:0000070; GO:0005634; GO:0051983; GO:0071173,attachment of spindle microtubules to kinetochore; cell division; condensed chromosome kinetochore; meiosis; mitotic sister chromatid segregation; nucleus; regulation of chromosome segregation; spindle assembly checkpoint,PF00400;,1.00E-166,CHOYP_BRAFLDRAFT_125481.1.1,,,,,,,BUB3_MOUSE,Mus musculus (Mouse),attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of chromosome segregation [GO:0051983]; spindle assembly checkpoint [GO:0071173] comp139870_c0_seq1,3090,31.7152,0.59540885,10317,29379,,,,,,,,,5.00E-32,CHOYP_LOC100368639.1.1,,,,,,,,, comp139872_c0_seq1,1397,29.2054,0.70682593,118,527,,,,,,,,,,,3.00E-28,ruditapes_c4087,,,,,,, comp139877_c0_seq1,3160,42.1203,0.54486409,2472,14281,,0,P07742,Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit),Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit),GO:0005524; GO:0006260; GO:0009263; GO:0051290; GO:0017076; GO:0004748; GO:0005971,"ATP binding; DNA replication; deoxyribonucleotide biosynthetic process; protein heterotetramerization; purine nucleotide binding; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ribonucleoside-diphosphate reductase complex",PF03477;PF02867;PF00317;,0,CHOYP_RIR1.2.2,,,,,,,RIR1_MOUSE,Mus musculus (Mouse),cell proliferation in forebrain [GO:0021846]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; male gonad development [GO:0008584]; mitotic cell cycle [GO:0000278]; protein heterotetramerization [GO:0051290]; protein oligomerization [GO:0051259]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ionizing radiation [GO:0010212]; retina development in camera-type eye [GO:0060041] comp139878_c0_seq1,2139,37.1669,0.81992355,2790,11345,,4.00E-29,Q4R979,RNA-binding protein 4 (RNA-binding motif protein 4),RNA-binding protein 4 (RNA-binding motif protein 4),GO:0002192; GO:0008380; GO:0030154; GO:0097167; GO:0010494; GO:0043153; GO:0003730; GO:0006397; GO:0035198; GO:0032055; GO:0035278; GO:0045947; GO:0016607; GO:0005730; GO:0000166; GO:0051149; GO:0097158; GO:0000381; GO:0046822; GO:0046685; GO:0051403; GO:0008270,"IRES-dependent translational initiation; RNA splicing; cell differentiation; circadian regulation of translation; cytoplasmic stress granule; entrainment of circadian clock by photoperiod; mRNA 3'-UTR binding; mRNA processing; miRNA binding; negative regulation of translation in response to stress; negative regulation of translation involved in gene silencing by miRNA; negative regulation of translational initiation; nuclear speck; nucleolus; nucleotide binding; positive regulation of muscle cell differentiation; pre-mRNA intronic pyrimidine-rich binding; regulation of alternative mRNA splicing, via spliceosome; regulation of nucleocytoplasmic transport; response to arsenic-containing substance; stress-activated MAPK cascade; zinc ion binding",PF00076;PF00098;,4.00E-51,CHOYP_1433G.2.2,3.00E-30,ruditapes2_c382,,,,,RBM4_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"cap-independent translational initiation [GO:0002190]; cell differentiation [GO:0030154]; circadian regulation of translation [GO:0097167]; entrainment of circadian clock by photoperiod [GO:0043153]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]" comp139878_c1_seq4,2382,41.4777,0.40763942,10,31,,1.00E-17,P12270,Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein),Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein),GO:0005524; GO:0000189; GO:0006404; GO:0005975; GO:0051301; GO:0035457; GO:0003682; GO:0019221; GO:0005868; GO:0070840; GO:0019898; GO:0015758; GO:0031072; GO:0000776; GO:0003729; GO:0031990; GO:0051019; GO:0007067; GO:0007077; GO:0072686; GO:0007094; GO:0046832; GO:0000122; GO:0045947; GO:0042405; GO:0031965; GO:0034399; GO:0044615; GO:0006999; GO:0005487; GO:0005654; GO:0031453; GO:0090267; GO:0046827; GO:0042307; GO:0042803; GO:0010827; GO:0010965; GO:1901673; GO:0070849; GO:0004828; GO:0006434; GO:0044281; GO:0055085; GO:0015631; GO:0016032,ATP binding; MAPK import into nucleus; RNA import into nucleus; carbohydrate metabolic process; cell division; cellular response to interferon-alpha; chromatin binding; cytokine-mediated signaling pathway; cytoplasmic dynein complex; dynein complex binding; extrinsic to membrane; glucose transport; heat shock protein binding; kinetochore; mRNA binding; mRNA export from nucleus in response to heat stress; mitogen-activated protein kinase binding; mitosis; mitotic nuclear envelope disassembly; mitotic spindle; mitotic spindle assembly checkpoint; negative regulation of RNA export from nucleus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of translational initiation; nuclear inclusion body; nuclear membrane; nuclear periphery; nuclear pore nuclear basket; nuclear pore organization; nucleocytoplasmic transporter activity; nucleoplasm; positive regulation of heterochromatin assembly; positive regulation of mitotic cell cycle spindle assembly checkpoint; positive regulation of protein export from nucleus; positive regulation of protein import into nucleus; protein homodimerization activity; regulation of glucose transport; regulation of mitotic sister chromatid separation; regulation of spindle assembly involved in mitosis; response to epidermal growth factor stimulus; serine-tRNA ligase activity; seryl-tRNA aminoacylation; small molecule metabolic process; transmembrane transport; tubulin binding; viral process,PF07926;,,,,,,,,,TPR_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp139879_c0_seq2,1016,47.0472,0.39324419,5,0,,0,Q7SZE5,Protein transport protein Sec23A (SEC23-related protein A),Protein transport protein Sec23A (SEC23-related protein A),GO:0030127; GO:0006888; GO:0000139; GO:0051216; GO:0048702; GO:0006886; GO:0035138; GO:0030868; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; Golgi membrane; cartilage development; embryonic neurocranium morphogenesis; intracellular protein transport; pectoral fin morphogenesis; smooth endoplasmic reticulum membrane; zinc ion binding,PF00626;PF08033;PF04815;PF04811;PF04810;,,,,,,,,,SC23A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cartilage development [GO:0051216]; embryonic neurocranium morphogenesis [GO:0048702]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; pectoral fin morphogenesis [GO:0035138] comp139879_c0_seq3,1151,38.1407,0.33475886,2,83,,,,,,,,,1.00E-136,CHOYP_SC23A.1.1,,,,,,,,, comp139879_c0_seq4,1559,45.4137,0.33617752,52,75,,0,Q9D662,Protein transport protein Sec23B (SEC23-related protein B),Protein transport protein Sec23B (SEC23-related protein B),GO:0030127; GO:0006888; GO:0000139; GO:0005789; GO:0033116; GO:0006886; GO:0048471; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; intracellular protein transport; perinuclear region of cytoplasm; zinc ion binding,PF00626;PF08033;PF04815;PF04811;PF04810;,0,CHOYP_SEC23B.1.1,,,,,,,SC23B_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886] comp139881_c0_seq1,1460,32.6027,0.5993261,35,10,,,,,,,,,2.00E-20,CHOYP_BRAFLDRAFT_120586.1.1,,,,,,,,, comp139881_c0_seq4,1639,43.3191,0.3926703,0,0,,6.00E-160,Q9JID6,Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase),Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase),GO:0005524; GO:0005789; GO:0001676; GO:0004467; GO:0005741; GO:0005778,ATP binding; endoplasmic reticulum membrane; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity; mitochondrial outer membrane; peroxisomal membrane,PF00501;,,,,,,,,,ACSL1_CAVPO,Cavia porcellus (Guinea pig), comp139881_c0_seq5,1639,43.2581,0.39461668,15,13,,2.00E-169,Q9JID6,Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase),Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase),GO:0005524; GO:0005789; GO:0001676; GO:0004467; GO:0005741; GO:0005778,ATP binding; endoplasmic reticulum membrane; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity; mitochondrial outer membrane; peroxisomal membrane,PF00501;,7.00E-59,CHOYP_ACSL1.1.1,,,,,,,ACSL1_CAVPO,Cavia porcellus (Guinea pig), comp139885_c0_seq2,557,41.2926,0.39702871,0,0,,3.00E-34,Q58EN8,Vacuolar protein sorting-associated protein 33B,Vacuolar protein sorting-associated protein 33B,GO:0035622; GO:0031902; GO:0005765; GO:0015031; GO:0006904,intrahepatic bile duct development; late endosome membrane; lysosomal membrane; protein transport; vesicle docking involved in exocytosis,PF00995;,4.00E-18,CHOYP_LOC100371979.1.1,,,,,,,VP33B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),intrahepatic bile duct development [GO:0035622]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp139885_c1_seq1,2684,33.6811,0.51240465,625,1736,,2.00E-71,Q6DGP2,Pre-mRNA-splicing factor syf2,Pre-mRNA-splicing factor syf2,GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF08231;,2.00E-99,CHOYP_BRAFLDRAFT_238139.1.1,,,,,,,SYF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA splicing, via spliceosome [GO:0000398]" comp139885_c1_seq2,1697,31.703,0.30750167,110,403,,4.00E-38,Q6DGP2,Pre-mRNA-splicing factor syf2,Pre-mRNA-splicing factor syf2,GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF08231;,,,,,,,,,SYF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA splicing, via spliceosome [GO:0000398]" comp139887_c1_seq1,2509,34.0773,0.95581595,4420,1422,,4.00E-36,Q9EQX4,Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2),Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2),GO:0051015; GO:0005509; GO:0005737; GO:0005856; GO:0032587,actin filament binding; calcium ion binding; cytoplasm; cytoskeleton; ruffle membrane,,1.00E-12,CHOYP_BRAFLDRAFT_81509.1.1,6.00E-47,ruditapes_c80,,,,,AIF1L_MOUSE,Mus musculus (Mouse), comp139888_c2_seq1,2632,42.9331,0.41846663,0,0,,0,Q14697,Neutral alpha-glucosidase AB (EC 3.2.1.84) (Alpha-glucosidase 2) (Glucosidase II subunit alpha),Neutral alpha-glucosidase AB (EC 3.2.1.84) (Alpha-glucosidase 2) (Glucosidase II subunit alpha),GO:0005794; GO:0030246; GO:0005788; GO:0033919; GO:0017177; GO:0042470; GO:0043687; GO:0018279; GO:0006457,"Golgi apparatus; carbohydrate binding; endoplasmic reticulum lumen; glucan 1,3-alpha-glucosidase activity; glucosidase II complex; melanosome; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding",PF13802;PF01055;,,,,,,,,,GANAB_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; protein folding [GO:0006457] comp139888_c2_seq2,2140,43.4579,0.41238658,0,0,,0,Q9BE70,Neutral alpha-glucosidase C (EC 3.2.1.-) (Fragment),Neutral alpha-glucosidase C (EC 3.2.1.-) (Fragment),GO:0030246; GO:0005975; GO:0004553,"carbohydrate binding; carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds",PF13802;PF01055;,0,CHOYP_LOC100492576.1.1,,,,,,,GANC_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),carbohydrate metabolic process [GO:0005975] comp139890_c0_seq4,1174,33.9012,0.3285045,2,6,,4.00E-17,A4IFC4,SH3 domain-binding glutamic acid-rich-like protein 2,SH3 domain-binding glutamic acid-rich-like protein 2,GO:0005634,nucleus,PF04908;,,,,,,,,,SH3L2_BOVIN,Bos taurus (Bovine), comp139893_c0_seq1,923,35.3196,0.50061978,19,248,,2.00E-59,Q6DJ25,Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10),Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09748;,5.00E-70,CHOYP_LOC100647975.2.2,,,,,,,MED10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"heart development [GO:0007507]; transcription, DNA-templated [GO:0006351]" comp139893_c0_seq2,778,35.09,0.43201047,17,102,,2.00E-08,Q1E0Q7,Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10),Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09748;,,,,,,,,,MED10_COCIM,Coccidioides immitis (strain RS) (Valley fever fungus),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp139895_c0_seq1,1885,47.6393,0.53325213,3,8,,6.00E-27,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp139895_c0_seq2,1727,43.1963,0.57136304,0,0,,,,,,,,,5.00E-17,CHOYP_SYNE1.1.1,,,,,,,,, comp139895_c0_seq5,932,47.103,0.4662674,0,7,,,,,,,,,2.00E-17,CHOYP_SYNE1.1.1,,,,,,,,, comp139895_c0_seq6,3614,45.5174,0.57844632,69,62,,4.00E-104,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp139896_c0_seq1,1616,41.3366,0.42083167,0,0,,0,Q5ZKI4,Coiled-coil domain-containing protein 93,Coiled-coil domain-containing protein 93,,,PF09762;,0,CHOYP_BRAFLDRAFT_92063.2.2,4.00E-91,ruditapes2_c2410,,,,,CCD93_CHICK,Gallus gallus (Chicken),Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] comp139896_c0_seq4,2036,42.1415,0.4431226,32,99,,0,Q5ZKI4,Coiled-coil domain-containing protein 93,Coiled-coil domain-containing protein 93,,,PF09762;,0,CHOYP_BRAFLDRAFT_92063.2.2,,,,,,,CCD93_CHICK,Gallus gallus (Chicken),Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] comp139897_c1_seq2,736,37.9076,0.53136363,51,35,,2.00E-08,Q2KI51,Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34),Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34),GO:0006915; GO:0005783; GO:0006417; GO:0006950,apoptotic process; endoplasmic reticulum; regulation of translation; response to stress,PF10488;,,,,,,,,,PR15A_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; regulation of translation [GO:0006417] comp139897_c1_seq3,470,35.5319,0.67750594,12,0,,2.00E-09,Q6IN02,Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog) (Progression elevated gene 3 protein) (PEG-3),Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog) (Progression elevated gene 3 protein) (PEG-3),GO:0006915; GO:0005783; GO:0030968; GO:0006417,apoptotic process; endoplasmic reticulum; endoplasmic reticulum unfolded protein response; regulation of translation,PF10488;,,,,,,,,,PR15A_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion starvation [GO:0072732]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cordycepin [GO:1904310]; cellular response to desipramine [GO:1904308]; cellular response to drug [GO:0035690]; cellular response to gold(3+) [GO:1904312]; cellular response to methamphetamine hydrochloride [GO:1904314]; cellular response to methyl methanesulfonate [GO:0072703]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to UV [GO:0034644]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of cell death [GO:0060548]; negative regulation of cell proliferation [GO:0008285]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein processing [GO:0010955]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein phosphorylation [GO:0001934]; regulation of angiogenesis [GO:0045765]; regulation of translation [GO:0006417]; response to cocaine [GO:0042220]; response to endoplasmic reticulum stress [GO:0034976]; response to environmental enrichment [GO:0090648]; response to immobilization stress [GO:0035902]; response to organic cyclic compound [GO:0014070] comp139899_c0_seq1,695,40.4317,0.62902842,21,72,,3.00E-36,O08623,Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62),Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62),GO:0042169; GO:0016235; GO:0006915; GO:0005776; GO:0030154; GO:0000932; GO:0031410; GO:0005783; GO:0005770; GO:0005764; GO:0016236; GO:0005634; GO:0001934; GO:0000407; GO:0051291; GO:0042803; GO:0005080; GO:0043122; GO:0043130; GO:0008270,SH2 domain binding; aggresome; apoptotic process; autophagic vacuole; cell differentiation; cytoplasmic mRNA processing body; cytoplasmic vesicle; endoplasmic reticulum; late endosome; lysosome; macroautophagy; nucleus; positive regulation of protein phosphorylation; pre-autophagosomal structure; protein heterooligomerization; protein homodimerization activity; protein kinase C binding; regulation of I-kappaB kinase/NF-kappaB cascade; ubiquitin binding; zinc ion binding,PF00564;PF00569;,,,,,,,,,SQSTM_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell differentiation [GO:0030154]; immune system process [GO:0002376]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein phosphorylation [GO:0001934]; protein heterooligomerization [GO:0051291]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of protein complex stability [GO:0061635]; ubiquitin-dependent protein catabolic process [GO:0006511] comp139899_c0_seq3,3090,41.6505,0.85251756,21,70,,1.00E-06,Q9P792,ZZ-type zinc finger-containing protein P35G2.11c,ZZ-type zinc finger-containing protein P35G2.11c,GO:0005794; GO:0008270,Golgi apparatus; zinc ion binding,PF16158;PF00569;,,,4.00E-18,ruditapes_c12404,,,,,YN8B_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp139899_c0_seq4,784,40.051,0.79534071,4,44,,4.00E-33,Q5RBA5,Sequestosome-1 (Ubiquitin-binding protein p62),Sequestosome-1 (Ubiquitin-binding protein p62),GO:0042169; GO:0006915; GO:0005776; GO:0030154; GO:0000932; GO:0031410; GO:0005783; GO:0005770; GO:0005764; GO:0016236; GO:0005634; GO:0005080; GO:0043122; GO:0043130; GO:0008270,SH2 domain binding; apoptotic process; autophagic vacuole; cell differentiation; cytoplasmic mRNA processing body; cytoplasmic vesicle; endoplasmic reticulum; late endosome; lysosome; macroautophagy; nucleus; protein kinase C binding; regulation of I-kappaB kinase/NF-kappaB cascade; ubiquitin binding; zinc ion binding,PF00564;PF00569;,,,,,,,,,SQSTM_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell differentiation [GO:0030154]; immune system process [GO:0002376]; macroautophagy [GO:0016236]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] comp139900_c0_seq1,596,45.8054,0.09737957,2,96,,2.00E-61,Q924M7,Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI),Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI),GO:0009298; GO:0005737; GO:0006013; GO:0004476; GO:0008270,GDP-mannose biosynthetic process; cytoplasm; mannose metabolic process; mannose-6-phosphate isomerase activity; zinc ion binding,PF01238;,,,,,,,,,MPI_MOUSE,Mus musculus (Mouse),GDP-mannose biosynthetic process [GO:0009298]; glycolytic process from mannose through fructose-6-phosphate [GO:0061619]; mannose to fructose-6-phosphate metabolic process [GO:0061611] comp139900_c1_seq1,1138,41.1248,0.50254658,11,315,,2.00E-25,Q83KZ1,Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI),Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI),GO:0009298; GO:0005975; GO:0005737; GO:0004476; GO:0008270,GDP-mannose biosynthetic process; carbohydrate metabolic process; cytoplasm; mannose-6-phosphate isomerase activity; zinc ion binding,PF01238;,2.00E-14,CHOYP_MPI.1.1,,,,,,,MANA_SHIFL,Shigella flexneri,carbohydrate metabolic process [GO:0005975]; GDP-mannose biosynthetic process [GO:0009298] comp139903_c1_seq1,740,46.0811,0.23085752,3,0,,,,,,,,,1.00E-70,CHOYP_BRAFLDRAFT_220356.1.6,,,,,,,,, comp139903_c1_seq2,1279,40.2658,0.39638325,92,181,,4.00E-159,Q9UBV2,Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L),Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L),GO:0007219; GO:0005789; GO:0016021; GO:0034976,Notch signaling pathway; endoplasmic reticulum membrane; integral to membrane; response to endoplasmic reticulum stress,PF00040;PF08238;,8.00E-152,CHOYP_BRAFLDRAFT_220356.3.6,,,,,,,SE1L1_HUMAN,Homo sapiens (Human),"endoplasmic reticulum mannose trimming [GO:1904380]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; Notch signaling pathway [GO:0007219]; protein secretion [GO:0009306]; protein stabilization [GO:0050821]; retrograde protein transport, ER to cytosol [GO:0030970]; triglyceride metabolic process [GO:0006641]" comp139904_c0_seq1,1372,41.2536,0.4662259,240,1625,,4.00E-83,Q5R6W5,Protein YIPF5 (YIP1 family member 5),Protein YIPF5 (YIP1 family member 5),GO:0030134; GO:0032580; GO:0070971; GO:0005789; GO:0016021; GO:0015031; GO:0060628; GO:0016192,ER to Golgi transport vesicle; Golgi cisterna membrane; endoplasmic reticulum exit site; endoplasmic reticulum membrane; integral to membrane; protein transport; regulation of ER to Golgi vesicle-mediated transport; vesicle-mediated transport,PF04893;,1.00E-73,CHOYP_LOC100186067.1.1,7.00E-18,ruditapes_c20429,,,,,YIPF5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; vesicle-mediated transport [GO:0016192] comp139906_c0_seq1,2425,39.3402,0.74091431,19,81,,8.00E-148,Q9UPI3,Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT),Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT),GO:0020037; GO:0015232; GO:0016021; GO:0005886; GO:0055085,heme binding; heme transporter activity; integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,FLVC2_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp139906_c0_seq2,2072,40.7819,0.82083239,3,190,,6.00E-27,Q6GNV7,Disrupted in renal carcinoma protein 2 homolog,Disrupted in renal carcinoma protein 2 homolog,GO:0016021; GO:0005765; GO:0055085,integral to membrane; lysosomal membrane; transmembrane transport,PF07690;,5.00E-113,CHOYP_BRAFLDRAFT_231234.1.1,,,,,,,DIRC2_XENLA,Xenopus laevis (African clawed frog),transmembrane transport [GO:0055085] comp139906_c0_seq3,2412,39.5108,0.74961181,25,32,,7.00E-148,Q9UPI3,Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT),Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT),GO:0020037; GO:0015232; GO:0016021; GO:0005886; GO:0055085,heme binding; heme transporter activity; integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,FLVC2_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp139906_c0_seq4,316,46.8354,0.52716714,19,18,,,,,,,,,8.00E-37,CHOYP_FLVC2.1.1,,,,,,,,, comp139907_c0_seq2,629,31.6375,0.57446954,10,45,,,,,,,,,,,3.00E-12,ruditapes_c27965,,,,,,, comp139909_c0_seq2,257,30.3502,1.02045052,8,6,,,,,,,,,,,1.00E-17,ruditapes_c376,,,,,,, comp139911_c5_seq1,931,45.9721,0.61138879,0,4,,1.00E-22,Q9H0F5,RING finger protein 38,E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38),GO:0008270,zinc ion binding,PF13639;,,,,,,,,,RNF38_HUMAN,Homo sapiens (Human),"male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]" comp139911_c5_seq2,1683,42.7213,0.58667802,0,0,,1.00E-21,Q9H0F5,RING finger protein 38,E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38),GO:0008270,zinc ion binding,PF13639;,,,,,,,,,RNF38_HUMAN,Homo sapiens (Human),"male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]" comp139911_c5_seq4,339,38.9381,0.70654044,0,0,,8.00E-12,Q8GUU2,E3 ubiquitin protein ligase RIE1 (EC 6.3.2.-) (Protein RING-FINGER FOR EMBRYOGENESIS 1),E3 ubiquitin protein ligase RIE1 (EC 6.3.2.-) (Protein RING-FINGER FOR EMBRYOGENESIS 1),GO:0009790; GO:0016021; GO:0016874; GO:0016567; GO:0008270,embryo development; integral to membrane; ligase activity; protein ubiquitination; zinc ion binding,PF13639;,,,,,,,,,RIE1_ARATH,Arabidopsis thaliana (Mouse-ear cress),embryo development ending in seed dormancy [GO:0009793]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp139918_c0_seq1,1587,40.9578,0.90981177,105,337,,3.00E-11,Q8CI17,Protein mab-21-like 3,Protein mab-21-like 3,,,PF03281;,,,,,,,,,MB213_MOUSE,Mus musculus (Mouse), comp139918_c0_seq2,2814,35.2168,0.53272727,0,0,,3.00E-168,P45985,Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK),Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK),GO:0005524; GO:0038095; GO:0007254; GO:0002755; GO:0035666; GO:0006915; GO:0071260; GO:0005829; GO:0045087; GO:0005634; GO:0018108; GO:0004672; GO:0004674; GO:0004713; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124,ATP binding; Fc-epsilon receptor signaling pathway; JNK cascade; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; apoptotic process; cellular response to mechanical stimulus; cytosol; innate immune response; nucleus; peptidyl-tyrosine phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway,PF00069;,1.00E-179,CHOYP_MP2K4.1.1,,,,,,,MP2K4_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; negative regulation of motor neuron apoptotic process [GO:2000672]; proteolysis in other organism [GO:0035897]; response to wounding [GO:0009611]; signal transduction [GO:0007165] comp139918_c0_seq3,2918,34.8869,0.52217238,8,49,,7.00E-168,P45985,Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK),Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK),GO:0005524; GO:0038095; GO:0007254; GO:0002755; GO:0035666; GO:0006915; GO:0071260; GO:0005829; GO:0045087; GO:0005634; GO:0018108; GO:0004672; GO:0004674; GO:0004713; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124,ATP binding; Fc-epsilon receptor signaling pathway; JNK cascade; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; apoptotic process; cellular response to mechanical stimulus; cytosol; innate immune response; nucleus; peptidyl-tyrosine phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway,PF00069;,4.00E-33,CHOYP_MP2K7.1.2,0,ruditapes_c12960,,,,,MP2K4_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; negative regulation of motor neuron apoptotic process [GO:2000672]; proteolysis in other organism [GO:0035897]; response to wounding [GO:0009611]; signal transduction [GO:0007165] comp139921_c1_seq1,2763,42.0195,0.6973418,86,970,,1.00E-25,O35625,Axin-1 (Axis inhibition protein 1) (Protein Fused),Axin-1 (Axis inhibition protein 1) (Protein Fused),GO:0005096; GO:0070411; GO:0016055; GO:0021881; GO:0090244; GO:0007257; GO:0006915; GO:0070016; GO:0048320; GO:0008013; GO:0030877; GO:0060823; GO:0005938; GO:0008219; GO:0043623; GO:0071407; GO:0016023; GO:0005881; GO:0031122; GO:0031410; GO:0007368; GO:0009950; GO:0048048; GO:0021797; GO:0071514; GO:0001701; GO:0016328; GO:0055001; GO:0030178; GO:0090090; GO:0045599; GO:0051248; GO:0034244; GO:0006913; GO:0005634; GO:0030910; GO:0001743; GO:0002039; GO:0048471; GO:0005886; GO:0046330; GO:0043507; GO:0033138; GO:0010800; GO:0032436; GO:2000060; GO:0045893; GO:0030511; GO:0051443; GO:0036342; GO:0014069; GO:0008022; GO:0030163; GO:0032947; GO:0051260; GO:0019901; GO:0000209; GO:0035412; GO:0007605; GO:0004871; GO:0038032,"GTPase activator activity; I-SMAD binding; Wnt receptor signaling pathway; Wnt receptor signaling pathway involved in forebrain neuron fate commitment; Wnt receptor signaling pathway involved in somitogenesis; activation of JUN kinase activity; apoptotic process; armadillo repeat domain binding; axial mesoderm formation; beta-catenin binding; beta-catenin destruction complex; canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; cell cortex; cell death; cellular protein complex assembly; cellular response to organic cyclic compound; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule; cytoplasmic microtubule organization; cytoplasmic vesicle; determination of left/right symmetry; dorsal/ventral axis specification; embryonic eye morphogenesis; forebrain anterior/posterior pattern specification; genetic imprinting; in utero embryonic development; lateral plasma membrane; muscle cell development; negative regulation of Wnt receptor signaling pathway; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of fat cell differentiation; negative regulation of protein metabolic process; negative regulation of transcription elongation from RNA polymerase II promoter; nucleocytoplasmic transport; nucleus; olfactory placode formation; optic placode formation; p53 binding; perinuclear region of cytoplasm; plasma membrane; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of transcription, DNA-dependent; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of ubiquitin-protein ligase activity; post-anal tail morphogenesis; postsynaptic density; protein C-terminus binding; protein catabolic process; protein complex scaffold; protein homooligomerization; protein kinase binding; protein polyubiquitination; regulation of catenin import into nucleus; sensory perception of sound; signal transducer activity; termination of G-protein coupled receptor signaling pathway",PF16646;PF08833;PF00778;PF00615;,7.00E-17,CHOYP_LOC100016298.1.1,,,,,,,AXIN1_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; axial mesoderm development [GO:0048318]; axial mesoderm formation [GO:0048320]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060823]; cell death [GO:0008219]; cellular protein complex assembly [GO:0043623]; cellular response to organic cyclic compound [GO:0071407]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; embryonic eye morphogenesis [GO:0048048]; forebrain anterior/posterior pattern specification [GO:0021797]; genetic imprinting [GO:0071514]; in utero embryonic development [GO:0001701]; muscle cell development [GO:0055001]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of Wnt signaling pathway [GO:0030178]; nucleocytoplasmic transport [GO:0006913]; olfactory placode formation [GO:0030910]; optic placode formation [GO:0001743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-anal tail morphogenesis [GO:0036342]; protein catabolic process [GO:0030163]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; regulation of catenin import into nucleus [GO:0035412]; regulation of protein phosphorylation [GO:0001932]; sensory perception of sound [GO:0007605]; Wnt-activated signaling pathway involved in forebrain neuron fate commitment [GO:0021881]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp139921_c1_seq2,3270,31.6514,0.3848002,250,2218,,,,,,,,,,,5.00E-11,ruditapes_c15771,,,,,,, comp139921_c2_seq1,479,36.5344,0.62745372,10,65,,5.00E-27,P57094,Axin-1 (Axis inhibition protein 1),Axin-1 (Axis inhibition protein 1),GO:0005096; GO:0021881; GO:0090244; GO:0007257; GO:0070016; GO:0048320; GO:0008013; GO:0030877; GO:0060823; GO:0005938; GO:0008219; GO:0071407; GO:0016023; GO:0005881; GO:0031122; GO:0007368; GO:0009950; GO:0048048; GO:0060272; GO:0031101; GO:0021797; GO:0055001; GO:0090090; GO:0045599; GO:0030910; GO:0001743; GO:0005886; GO:0046330; GO:0014069; GO:0042803; GO:0019901; GO:0035412; GO:0004871; GO:0038032,GTPase activator activity; Wnt receptor signaling pathway involved in forebrain neuron fate commitment; Wnt receptor signaling pathway involved in somitogenesis; activation of JUN kinase activity; armadillo repeat domain binding; axial mesoderm formation; beta-catenin binding; beta-catenin destruction complex; canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; cell cortex; cell death; cellular response to organic cyclic compound; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule; cytoplasmic microtubule organization; determination of left/right symmetry; dorsal/ventral axis specification; embryonic eye morphogenesis; embryonic skeletal joint morphogenesis; fin regeneration; forebrain anterior/posterior pattern specification; muscle cell development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of fat cell differentiation; olfactory placode formation; optic placode formation; plasma membrane; positive regulation of JNK cascade; postsynaptic density; protein homodimerization activity; protein kinase binding; regulation of catenin import into nucleus; signal transducer activity; termination of G-protein coupled receptor signaling pathway,PF16646;PF08833;PF00778;PF00615;,,,,,,,,,AXIN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of JUN kinase activity [GO:0007257]; axial mesoderm formation [GO:0048320]; canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060823]; cell death [GO:0008219]; cellular response to organic cyclic compound [GO:0071407]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; embryonic eye morphogenesis [GO:0048048]; embryonic skeletal joint morphogenesis [GO:0060272]; eye development [GO:0001654]; fin regeneration [GO:0031101]; forebrain anterior/posterior pattern specification [GO:0021797]; forebrain development [GO:0030900]; muscle cell development [GO:0055001]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of Wnt signaling pathway [GO:0030178]; neural plate anterior/posterior regionalization [GO:0021999]; olfactory placode formation [GO:0030910]; optic placode formation [GO:0001743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; regulation of catenin import into nucleus [GO:0035412]; Wnt-activated signaling pathway involved in forebrain neuron fate commitment [GO:0021881]; Wnt signaling pathway involved in somitogenesis [GO:0090244] comp139924_c0_seq6,2357,37.3356,0.49330811,174,802,,3.00E-87,Q6NSJ0,Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-),Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-),GO:0005975; GO:0004553; GO:0016021; GO:0031965; GO:0043568; GO:0051897; GO:0048741,"carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; integral to membrane; nuclear membrane; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of protein kinase B signaling cascade; skeletal muscle fiber development",PF01055;,,,,,,,,,K1161_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; skeletal muscle fiber development [GO:0048741] comp139925_c0_seq1,2585,37.6402,0.66922012,1965,256,,8.00E-49,Q96DY2,IQ domain-containing protein D,IQ domain-containing protein D,,,PF00612;,9.00E-117,CHOYP_LOC100376807.1.1,,,,,,,IQCD_HUMAN,Homo sapiens (Human), comp139926_c1_seq1,1957,41.5943,0.5934306,0,0,,3.00E-86,Q60803,TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN),TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN),GO:0035631; GO:0008063; GO:0006915; GO:0005768; GO:0045087; GO:0009898; GO:0032088; GO:0042981; GO:0050688; GO:0032648; GO:0030162; GO:0002224; GO:0033209; GO:0004842; GO:0008270,CD40 receptor complex; Toll signaling pathway; apoptotic process; endosome; innate immune response; internal side of plasma membrane; negative regulation of NF-kappaB transcription factor activity; regulation of apoptotic process; regulation of defense response to virus; regulation of interferon-beta production; regulation of proteolysis; toll-like receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,TRAF3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp139926_c1_seq10,1419,43.1994,0.62865812,0,0,,9.00E-23,Q6IWL4,TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),GO:0050852; GO:0007250; GO:0046849; GO:0048468; GO:0005737; GO:0045087; GO:0070498; GO:0009887; GO:0001503; GO:0043123; GO:0043507; GO:0031666; GO:0045672; GO:0045893; GO:0070534; GO:0051865; GO:0042981; GO:0009617; GO:0009615; GO:0004871; GO:0004842; GO:0008270,"T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; bone remodeling; cell development; cytoplasm; innate immune response; interleukin-1-mediated signaling pathway; organ morphogenesis; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of osteoclast differentiation; positive regulation of transcription, DNA-dependent; protein K63-linked ubiquitination; protein autoubiquitination; regulation of apoptotic process; response to bacterium; response to virus; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding",PF02176;,,,,,,,,,TRAF6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"innate immune response [GO:0045087]; positive regulation of transcription, DNA-templated [GO:0045893]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; response to bacterium [GO:0009617]; response to virus [GO:0009615]; signal transduction [GO:0007165]" comp139926_c1_seq11,882,45.805,0.7393134,0,0,,3.00E-90,Q60803,TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN),TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN),GO:0035631; GO:0008063; GO:0006915; GO:0005768; GO:0045087; GO:0009898; GO:0032088; GO:0042981; GO:0050688; GO:0032648; GO:0030162; GO:0002224; GO:0033209; GO:0004842; GO:0008270,CD40 receptor complex; Toll signaling pathway; apoptotic process; endosome; innate immune response; internal side of plasma membrane; negative regulation of NF-kappaB transcription factor activity; regulation of apoptotic process; regulation of defense response to virus; regulation of interferon-beta production; regulation of proteolysis; toll-like receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,3.00E-53,CHOYP_TRAF3.1.4,,,,,,,TRAF3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp139926_c1_seq12,401,36.9077,0.23408531,5,0,,4.00E-06,P93471,E3 ubiquitin-protein ligase COP1 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1),E3 ubiquitin-protein ligase COP1 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1),GO:0005737; GO:0016874; GO:0005634; GO:0016567; GO:0009585; GO:0008270,"cytoplasm; ligase activity; nucleus; protein ubiquitination; red, far-red light phototransduction; zinc ion binding",PF00400;,,,,,,,,,COP1_PEA,Pisum sativum (Garden pea),"red, far-red light phototransduction [GO:0009585]" comp139926_c1_seq3,2168,42.0203,0.6209955,0,2,,3.00E-133,Q13114,TNF receptor-associated factor 3 (EC 6.3.2.-) (CAP-1) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1),TNF receptor-associated factor 3 (EC 6.3.2.-) (CAP-1) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1),GO:0035631; GO:0035666; GO:0008063; GO:0006915; GO:0005829; GO:0005768; GO:0045087; GO:0009898; GO:0005739; GO:0032088; GO:0032480; GO:0042981; GO:0050688; GO:0032648; GO:0030162; GO:0004871; GO:0034138; GO:0034142; GO:0033209; GO:0004842; GO:0008270,CD40 receptor complex; TRIF-dependent toll-like receptor signaling pathway; Toll signaling pathway; apoptotic process; cytosol; endosome; innate immune response; internal side of plasma membrane; mitochondrion; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production; regulation of apoptotic process; regulation of defense response to virus; regulation of interferon-beta production; regulation of proteolysis; signal transducer activity; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,2.00E-35,CHOYP_TRAF3.4.4,,,,,,,TRAF3_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon production [GO:0032480]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp139926_c1_seq4,1556,43.1234,0.70717292,0,4,,3.00E-66,O00463,TNF receptor-associated factor 5 (RING finger protein 84),TNF receptor-associated factor 5 (RING finger protein 84),GO:0035631; GO:0006915; GO:0005813; GO:0005829; GO:0009898; GO:0043123; GO:0051092; GO:0008284; GO:0042981; GO:0004871; GO:0007165; GO:0004842; GO:0008270,CD40 receptor complex; apoptotic process; centrosome; cytosol; internal side of plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of cell proliferation; regulation of apoptotic process; signal transducer activity; signal transduction; ubiquitin-protein ligase activity; zinc ion binding,PF00097;PF02176;,,,,,,,,,TRAF5_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165] comp139926_c1_seq5,1705,43.1672,0.6403185,0,0,,1.00E-13,Q54NN4,TNF receptor-associated factor family protein DDB_G0285149,TNF receptor-associated factor family protein DDB_G0285149,GO:0005737; GO:0004842; GO:0008270,cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF00917;PF02176;,7.00E-53,CHOYP_TRAF3.1.4,,,,,,,Y8514_DICDI,Dictyostelium discoideum (Slime mold), comp139926_c1_seq6,1494,42.905,0.60412998,0,0,,2.00E-10,Q54C11,TNF receptor-associated factor family protein DDB_G0293202,TNF receptor-associated factor family protein DDB_G0293202,GO:0005737; GO:0004842; GO:0008270,cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,Y3202_DICDI,Dictyostelium discoideum (Slime mold), comp139926_c1_seq7,1345,42.8996,0.6955491,0,0,,1.00E-59,Q13077,TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6),TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6),GO:0006915; GO:0005737; GO:0051092; GO:0006461; GO:2001236; GO:0007165; GO:0008270,apoptotic process; cytoplasm; positive regulation of NF-kappaB transcription factor activity; protein complex assembly; regulation of extrinsic apoptotic signaling pathway; signal transduction; zinc ion binding,PF16673;,,,,,,,,,TRAF1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein complex assembly [GO:0006461]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; signal transduction [GO:0007165] comp139926_c1_seq9,1018,46.2672,0.80019435,0,0,,,,,,,,,1.00E-34,CHOYP_TRAF3.4.4,,,,,,,,, comp139927_c0_seq1,1087,38.6385,0.3458991,779,4332,,1.00E-32,Q2TBS2,"39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21)","39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF00829;,,,,,,,,,RM21_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp139930_c0_seq2,1976,37.0951,0.69068143,134,1320,,3.00E-34,Q03017,NF-kappa-B inhibitor cactus,NF-kappa-B inhibitor cactus,GO:0008063; GO:0019732; GO:0005737; GO:0042994; GO:0046843; GO:0009950; GO:0030097; GO:0045087; GO:0007399; GO:0031594; GO:0006909; GO:0006967; GO:0006974; GO:0008134,Toll signaling pathway; antifungal humoral response; cytoplasm; cytoplasmic sequestering of transcription factor; dorsal appendage formation; dorsal/ventral axis specification; hemopoiesis; innate immune response; nervous system development; neuromuscular junction; phagocytosis; positive regulation of antifungal peptide biosynthetic process; response to DNA damage stimulus; transcription factor binding,PF00023;PF12796;,,,2.00E-51,ruditapes_c29477,,,,,CACT_DROME,Drosophila melanogaster (Fruit fly),antifungal humoral response [GO:0019732]; antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic sequestering of transcription factor [GO:0042994]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal appendage formation [GO:0046843]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of protein import into nucleus [GO:0042308]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of antifungal peptide biosynthetic process [GO:0006967]; response to fungus [GO:0009620]; Toll signaling pathway [GO:0008063] comp139932_c0_seq1,1562,40.525,0.55229705,0,0,,2.00E-107,P25490,Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1),Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1),GO:0031011; GO:0003723; GO:0001078; GO:0030154; GO:0034644; GO:0000724; GO:0000400; GO:0016363; GO:0005886; GO:0010225; GO:0007283; GO:0003713; GO:0003714; GO:0044212; GO:0008270,Ino80 complex; RNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cell differentiation; cellular response to UV; double-strand break repair via homologous recombination; four-way junction DNA binding; nuclear matrix; plasma membrane; response to UV-C; spermatogenesis; transcription coactivator activity; transcription corepressor activity; transcription regulatory region DNA binding; zinc ion binding,PF00096;,,,,,,,,,TYY1_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to UV-C [GO:0010225]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp139932_c0_seq3,1579,40.4053,0.54930887,0,0,,2.00E-98,Q2FAY8,Transcription factor YY2 (Yin and yang 2) (YY-2),Transcription factor YY2 (Yin and yang 2) (YY-2),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,TYY2_RATRT,Rattus rattus (Black rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139932_c0_seq4,1666,40.3962,0.53702033,0,0,,3.00E-24,A6QQW0,Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN143_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp139932_c0_seq5,1649,40.5094,0.53982843,0,0,,7.00E-57,P22227,Zinc finger protein 42 (Zfp-42) (Reduced expression protein 1) (REX-1) (mREX-1),Zinc finger protein 42 (Zfp-42) (Reduced expression protein 1) (REX-1) (mREX-1),GO:0005737; GO:0001701; GO:0046872; GO:0005634; GO:0043234; GO:2000653; GO:0006355; GO:0043565; GO:0007286; GO:0006351,"cytoplasm; in utero embryonic development; metal ion binding; nucleus; protein complex; regulation of genetic imprinting; regulation of transcription, DNA-dependent; sequence-specific DNA binding; spermatid development; transcription, DNA-dependent",,1.00E-93,CHOYP_LOC100378209.1.2,,,,,,,ZFP42_MOUSE,Mus musculus (Mouse),"in utero embryonic development [GO:0001701]; regulation of genetic imprinting [GO:2000653]; regulation of transcription, DNA-templated [GO:0006355]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]" comp139937_c1_seq1,1806,39.4241,0.57467718,2499,686,,2.00E-164,Q9Y5B8,Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7),Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0007420; GO:0005813; GO:0060830; GO:0007368; GO:0003351; GO:0042073; GO:0060972; GO:0046872; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; brain development; centrosome; ciliary receptor clustering involved in smoothened signaling pathway; determination of left/right symmetry; epithelial cilium movement; intraflagellar transport; left/right pattern formation; metal ion binding; nucleoside diphosphate kinase activity,PF00334;,3.00E-82,CHOYP_NDK7.1.1,1.00E-16,ruditapes_c11640,,,,,NDK7_HUMAN,Homo sapiens (Human),CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] comp139938_c3_seq1,4484,42.6182,0.34891711,438,2182,,0,A2ABV5,Mediator of RNA polymerase II transcription subunit 14 (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170),Mediator of RNA polymerase II transcription subunit 14 (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170),GO:0001104; GO:0030521; GO:0016592; GO:0045944; GO:0004872; GO:0019827; GO:0003713; GO:0006367,RNA polymerase II transcription cofactor activity; androgen receptor signaling pathway; mediator complex; positive regulation of transcription from RNA polymerase II promoter; receptor activity; stem cell maintenance; transcription coactivator activity; transcription initiation from RNA polymerase II promoter,PF08638;,2.00E-40,CHOYP_PHUM_PHUM128490.1.1,,,,,,,MED14_MOUSE,Mus musculus (Mouse),"androgen receptor signaling pathway [GO:0030521]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; stem cell population maintenance [GO:0019827]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp139941_c0_seq1,2759,39.3621,0.68941456,91,62,,0,Q9PTR5,Lissencephaly-1 homolog,Lissencephaly-1 homolog,GO:0000235; GO:0048854; GO:0005938; GO:0051301; GO:0006928; GO:0021987; GO:0021540; GO:0000132; GO:0000776; GO:0005875; GO:0005815; GO:0031023; GO:0007067; GO:0005634; GO:0006810,astral microtubule; brain morphogenesis; cell cortex; cell division; cellular component movement; cerebral cortex development; corpus callosum morphogenesis; establishment of mitotic spindle orientation; kinetochore; microtubule associated complex; microtubule organizing center; microtubule organizing center organization; mitosis; nucleus; transport,PF08513;PF00400;,0,CHOYP_LIS1.1.1,,,,,,,LIS1_CHICK,Gallus gallus (Chicken),acrosome assembly [GO:0001675]; actin cytoskeleton organization [GO:0030036]; adult locomotory behavior [GO:0008344]; ameboidal-type cell migration [GO:0001667]; auditory receptor cell development [GO:0060117]; brain morphogenesis [GO:0048854]; cell division [GO:0051301]; chemical synaptic transmission [GO:0007268]; cochlea development [GO:0090102]; corpus callosum morphogenesis [GO:0021540]; cortical microtubule organization [GO:0043622]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity of embryonic epithelium [GO:0042249]; germ cell development [GO:0007281]; hippocampus development [GO:0021766]; layer formation in cerebral cortex [GO:0021819]; learning or memory [GO:0007611]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; negative regulation of JNK cascade [GO:0046329]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuromuscular process controlling balance [GO:0050885]; neuron migration [GO:0001764]; nuclear envelope disassembly [GO:0051081]; nuclear migration [GO:0007097]; osteoclast development [GO:0036035]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of embryonic development [GO:0040019]; protein secretion [GO:0009306]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; transmission of nerve impulse [GO:0019226]; vesicle transport along microtubule [GO:0047496] comp139941_c0_seq2,2105,37.9097,0.73737165,3,0,,8.00E-23,Q42384,Protein pleiotropic regulatory locus 1 (Protein PRL1) (MOS4-associated complex protein 2) (MAC protein 2),Protein pleiotropic regulatory locus 1 (Protein PRL1) (MOS4-associated complex protein 2) (MAC protein 2),GO:0080008; GO:0048825; GO:0009870; GO:0010204; GO:0042742; GO:0050832; GO:0009755; GO:0045087; GO:0045892; GO:0005634; GO:0016567; GO:0006508; GO:0009749; GO:0048364; GO:0010182,"Cul4-RING ubiquitin ligase complex; cotyledon development; defense response signaling pathway, resistance gene-dependent; defense response signaling pathway, resistance gene-independent; defense response to bacterium; defense response to fungus; hormone-mediated signaling pathway; innate immune response; negative regulation of transcription, DNA-dependent; nucleus; protein ubiquitination; proteolysis; response to glucose stimulus; root development; sugar mediated signaling pathway",PF00400;,,,,,,,,,PRL1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cotyledon development [GO:0048825]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; fruit development [GO:0010154]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; leaf development [GO:0048366]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription, DNA-templated [GO:0045892]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; response to glucose [GO:0009749]; root development [GO:0048364]; sugar mediated signaling pathway [GO:0010182]" comp139941_c1_seq1,859,35.6228,0.3334343,27,87,,2.00E-47,Q9Z0F4,Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP),Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP),GO:0016324; GO:0006915; GO:0005509; GO:0007113; GO:0005783; GO:0030175; GO:0008285; GO:0005654; GO:0070886; GO:0090004; GO:0043495; GO:0006974; GO:0042383,apical plasma membrane; apoptotic process; calcium ion binding; endomitotic cell cycle; endoplasmic reticulum; filopodium; negative regulation of cell proliferation; nucleoplasm; positive regulation of calcineurin-NFAT signaling cascade; positive regulation of establishment of protein localization to plasma membrane; protein anchor; response to DNA damage stimulus; sarcolemma,PF13499;,4.00E-96,CHOYP_LOC756594.1.1,,,,,,,CIB1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; endomitotic cell cycle [GO:0007113]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163] comp139943_c0_seq1,1742,38.9208,0.4477308,0,4,,7.00E-124,Q5R754,Cyclin-dependent kinase-like 2 (EC 2.7.11.22),Cyclin-dependent kinase-like 2 (EC 2.7.11.22),GO:0005524; GO:0004693; GO:0005737; GO:0005634,ATP binding; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; nucleus,PF00069;,3.00E-133,CHOYP_NEMVEDRAFT_V1G122840.2.2,,,,,,,CDKL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp139943_c0_seq3,1950,40.1538,0.44645321,27,0,,3.00E-160,Q5R754,Cyclin-dependent kinase-like 2 (EC 2.7.11.22),Cyclin-dependent kinase-like 2 (EC 2.7.11.22),GO:0005524; GO:0004693; GO:0005737; GO:0005634,ATP binding; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; nucleus,PF00069;,0,CHOYP_NEMVEDRAFT_V1G122840.2.2,,,,,,,CDKL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp139944_c1_seq4,1550,39.5484,0.48187331,0,0,,1.00E-102,Q17QN2,Target of EGR1 protein 1,Target of EGR1 protein 1,GO:0046872; GO:0016607; GO:0003676; GO:0005730,metal ion binding; nuclear speck; nucleic acid binding; nucleolus,PF04857;PF00642;,,,,,,,,,TOE1_BOVIN,Bos taurus (Bovine), comp139944_c1_seq6,1290,39.6899,0.4564505,0,0,,6.00E-40,Q9D2E2,Target of EGR1 protein 1,Target of EGR1 protein 1,GO:0046872; GO:0016607; GO:0003676; GO:0005730,metal ion binding; nuclear speck; nucleic acid binding; nucleolus,PF04857;PF00642;,,,,,,,,,TOE1_MOUSE,Mus musculus (Mouse),"RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]" comp139946_c0_seq1,1792,40.067,0.50882907,28,356,,4.00E-57,Q5JHP2,Replication factor C small subunit (RFC small subunit) (Clamp loader small subunit) [Cleaved into: Pko RFC intein],Replication factor C small subunit (RFC small subunit) (Clamp loader small subunit) [Cleaved into: Pko RFC intein],GO:0005524; GO:0006310; GO:0006281; GO:0006260; GO:0004519; GO:0009378; GO:0016539; GO:0043565,ATP binding; DNA recombination; DNA repair; DNA replication; endonuclease activity; four-way junction helicase activity; intein-mediated protein splicing; sequence-specific DNA binding,PF01381;PF14528;PF08542;PF05496;,6.00E-174,CHOYP_RFC2.2.2,,,,,,,RFCS_PYRKO,Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539] comp139946_c0_seq2,2535,37.002,0.42172956,195,1138,,9.00E-47,P0C7N7,Replication factor C subunit 2 (Replication factor C2),Replication factor C subunit 2 (Replication factor C2),GO:0005524; GO:0003677; GO:0006260; GO:0017111; GO:0005634,ATP binding; DNA binding; DNA replication; nucleoside-triphosphatase activity; nucleus,PF00004;PF08542;,,,,,,,,,RFC2_PHANO,Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum),DNA-dependent DNA replication [GO:0006261] comp139946_c0_seq6,2786,37.0782,0.46359394,391,1079,,0,P53033,Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40),Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40),GO:0005524; GO:0003677; GO:0006260; GO:0000724; GO:0005654; GO:0017111,ATP binding; DNA binding; DNA replication; double-strand break repair via homologous recombination; nucleoplasm; nucleoside-triphosphatase activity,PF00004;PF08542;,,,4.00E-31,ruditapes_c27201,5.00E-113,AM861838.p.cg.6,8,,RFC2_CHICK,Gallus gallus (Chicken),DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724] comp139949_c0_seq1,784,46.0459,0.33894701,75,47,,1.00E-51,Q9BVR0,Putative HERC2-like protein 3,Putative HERC2-like protein 3,GO:0046872; GO:0004842,metal ion binding; ubiquitin-protein ligase activity,PF06701;,,,,,,,,,HRC23_HUMAN,Homo sapiens (Human), comp139949_c1_seq1,4136,49.9516,0.39701441,53,4,,0,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,0,CHOYP_HERC2.1.1,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp139949_c1_seq2,1721,50.7844,0.39069265,14,7,,,,,,,,,8.00E-33,CHOYP_RL17.3.7,,,,,,,,, comp139949_c1_seq3,2492,48.8764,0.4042796,2,0,,0,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,0,CHOYP_HERC2.1.1,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp139949_c1_seq4,863,49.5944,0.38065079,0,0,,3.00E-15,Q9V4N3,Cytochrome b5 (CYTB5),Cytochrome b5 (CYTB5),GO:0005789; GO:0020037; GO:0016021; GO:0005811; GO:0046872; GO:0055114; GO:0045610; GO:0035206,endoplasmic reticulum membrane; heme binding; integral to membrane; lipid particle; metal ion binding; oxidation-reduction process; regulation of hemocyte differentiation; regulation of hemocyte proliferation,PF00173;,,,,,,,,,CYB5_DROME,Drosophila melanogaster (Fruit fly),oxidation-reduction process [GO:0055114]; regulation of hemocyte differentiation [GO:0045610]; regulation of hemocyte proliferation [GO:0035206] comp139951_c0_seq1,1783,35.2776,0.40491089,129,442,,6.00E-83,Q7F9U3,"Electron transfer flavoprotein subunit beta, mitochondrial (Beta-ETF)","Electron transfer flavoprotein subunit beta, mitochondrial (Beta-ETF)",GO:0009055; GO:0005759; GO:0055114,electron carrier activity; mitochondrial matrix; oxidation-reduction process,PF01012;,,,,,,,,,ETFB_ORYSJ,Oryza sativa subsp. japonica (Rice),oxidation-reduction process [GO:0055114] comp139951_c0_seq2,1796,35.245,0.40375436,259,1292,,3.00E-100,P38117,Electron transfer flavoprotein subunit beta (Beta-ETF),Electron transfer flavoprotein subunit beta (Beta-ETF),GO:0009055; GO:0005759; GO:0022904; GO:0044281,electron carrier activity; mitochondrial matrix; respiratory electron transport chain; small molecule metabolic process,PF01012;,8.00E-135,CHOYP_ISCW_ISCW012010.1.1,,,,,,,ETFB_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904] comp139953_c0_seq1,2210,42.3982,0.37323103,159,847,,0,Q4G056,Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-),Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-),GO:0017005; GO:0005737; GO:0006302; GO:0003690; GO:0004527; GO:0090305; GO:0005634; GO:0003697,3'-tyrosyl-DNA phosphodiesterase activity; cytoplasm; double-strand break repair; double-stranded DNA binding; exonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; single-stranded DNA binding,PF06087;,1.00E-70,CHOYP_TYDP1.1.1,,,,,,,TYDP1_RAT,Rattus norvegicus (Rat),DNA repair [GO:0006281] comp139954_c0_seq1,1940,43.2474,0.46738919,14,98,,1.00E-164,Q54ZW0,Putative phagocytic receptor 1b (SrfA-induced gene C protein),Putative phagocytic receptor 1b (SrfA-induced gene C protein),GO:0008283; GO:0031589; GO:0005887; GO:0006909; GO:0072657; GO:0033299; GO:0030587; GO:0004888,cell proliferation; cell-substrate adhesion; integral to plasma membrane; phagocytosis; protein localization to membrane; secretion of lysosomal enzymes; sorocarp development; transmembrane signaling receptor activity,PF02990;,,,,,,,,,PHG1B_DICDI,Dictyostelium discoideum (Slime mold),cell proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; phagocytosis [GO:0006909]; protein localization to membrane [GO:0072657]; secretion of lysosomal enzymes [GO:0033299]; sorocarp development [GO:0030587] comp139954_c0_seq2,1862,43.7164,0.46538691,12,34,,0,Q9DBU0,Transmembrane 9 superfamily member 1,Transmembrane 9 superfamily member 1,GO:0000421; GO:0006914; GO:0031410; GO:0016021; GO:0005765,autophagic vacuole membrane; autophagy; cytoplasmic vesicle; integral to membrane; lysosomal membrane,PF02990;,0,CHOYP_LOC100555295.1.1,,,,,,,TM9S1_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914] comp139955_c0_seq1,2544,44.8113,0.32913947,767,2611,,6.00E-42,Q923D5,WW domain-binding protein 11 (WBP-11) (Splicing factor that interacts with PQBP-1 and PP1),WW domain-binding protein 11 (WBP-11) (Splicing factor that interacts with PQBP-1 and PP1),GO:0008380; GO:0005737; GO:0006397; GO:0016607; GO:0008599; GO:0006364,RNA splicing; cytoplasm; mRNA processing; nuclear speck; protein phosphatase type 1 regulator activity; rRNA processing,PF09429;,2.00E-81,CHOYP_WBP11.1.1,,,,,,,WBP11_MOUSE,Mus musculus (Mouse),"mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364]" comp139958_c1_seq1,3730,38.7399,0.46808535,28,159,,2.00E-08,Q6ZQ29,Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2),Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2),GO:0005524; GO:0031572; GO:0030036; GO:0000186; GO:0030659; GO:0005856; GO:0030425; GO:0048041; GO:0016021; GO:0005730; GO:0046330; GO:0032874; GO:0004674; GO:0008360; GO:0051403,ATP binding; G2 DNA damage checkpoint; actin cytoskeleton organization; activation of MAPKK activity; cytoplasmic vesicle membrane; cytoskeleton; dendrite; focal adhesion assembly; integral to membrane; nucleolus; positive regulation of JNK cascade; positive regulation of stress-activated MAPK cascade; protein serine/threonine kinase activity; regulation of cell shape; stress-activated MAPK cascade,PF00069;,,,,,,,,,TAOK2_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; activation of MAPKK activity [GO:0000186]; cellular response to DNA damage stimulus [GO:0006974]; focal adhesion assembly [GO:0048041]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; regulation of cell shape [GO:0008360]; stress-activated MAPK cascade [GO:0051403] comp139958_c1_seq2,3758,38.6376,0.46719763,74,353,,3.00E-11,O15075,Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1),Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1),GO:0005524; GO:0048675; GO:0007417; GO:0021952; GO:0048813; GO:0016197; GO:0030900; GO:0005887; GO:0035556; GO:0001764; GO:0004672; GO:0004674; GO:0005057; GO:0009615,ATP binding; axon extension; central nervous system development; central nervous system projection neuron axonogenesis; dendrite morphogenesis; endosomal transport; forebrain development; integral to plasma membrane; intracellular signal transduction; neuron migration; protein kinase activity; protein serine/threonine kinase activity; receptor signaling protein activity; response to virus,PF03607;PF00069;,,,,,,,,,DCLK1_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; central nervous system development [GO:0007417]; central nervous system projection neuron axonogenesis [GO:0021952]; dendrite morphogenesis [GO:0048813]; endosomal transport [GO:0016197]; forebrain development [GO:0030900]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615] comp139961_c1_seq1,1719,41.0704,0.68752878,75,309,,1.00E-135,Q3SZP8,Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein),Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein),GO:0005671; GO:0003677; GO:0000125; GO:0003682; GO:0005694; GO:0043966; GO:0004402; GO:0007067; GO:0072686; GO:0031063; GO:0001932; GO:0031647; GO:0006355; GO:0090043; GO:0006351; GO:0008270,"Ada2/Gcn5/Ada3 transcription activator complex; DNA binding; PCAF complex; chromatin binding; chromosome; histone H3 acetylation; histone acetyltransferase activity; mitosis; mitotic spindle; regulation of histone deacetylation; regulation of protein phosphorylation; regulation of protein stability; regulation of transcription, DNA-dependent; regulation of tubulin deacetylation; transcription, DNA-dependent; zinc ion binding",PF00249;PF04433;,,,,,,,,,TAD2A_BOVIN,Bos taurus (Bovine),"chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; mitotic nuclear division [GO:0007067]; positive regulation of histone acetylation [GO:0035066]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; transcription, DNA-templated [GO:0006351]" comp139962_c0_seq12,2282,36.7222,0.43134423,0,0,,6.00E-11,A2AM29,Protein AF-9 (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog),Protein AF-9 (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog),GO:0009952; GO:0090090; GO:0005634; GO:2000096; GO:0006355; GO:0007379; GO:0006351,"anterior/posterior pattern specification; negative regulation of canonical Wnt receptor signaling pathway; nucleus; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; regulation of transcription, DNA-dependent; segment specification; transcription, DNA-dependent",PF03366;,,,,,,,,,AF9_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; transcription, DNA-templated [GO:0006351]" comp139962_c0_seq8,2252,36.5897,0.44050061,0,5,,6.00E-11,A2AM29,Protein AF-9 (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog),Protein AF-9 (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog),GO:0009952; GO:0090090; GO:0005634; GO:2000096; GO:0006355; GO:0007379; GO:0006351,"anterior/posterior pattern specification; negative regulation of canonical Wnt receptor signaling pathway; nucleus; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; regulation of transcription, DNA-dependent; segment specification; transcription, DNA-dependent",PF03366;,,,,,,,,,AF9_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; transcription, DNA-templated [GO:0006351]" comp139963_c0_seq2,1673,36.2224,0.60616922,115,640,,7.00E-77,Q6NWX7,N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A),N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A),GO:0018016; GO:0035572; GO:0035573; GO:0007059; GO:0005634; GO:0008276; GO:0007051,N-terminal peptidyl-proline dimethylation; N-terminal peptidyl-serine dimethylation; N-terminal peptidyl-serine trimethylation; chromosome segregation; nucleus; protein methyltransferase activity; spindle organization,PF05891;,4.00E-36,CHOYP_NTM1A.1.1,,,,,,,NTM1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chromosome segregation [GO:0007059]; N-terminal peptidyl-alanine methylation [GO:0018011]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-proline methylation [GO:0035568]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine methylation [GO:0035570]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051] comp139974_c0_seq1,1483,39.0425,0.55254775,3386,10485,,3.00E-95,Q58ED9,N-alpha-acetyltransferase 20 (EC 2.3.1.88) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit),N-alpha-acetyltransferase 20 (EC 2.3.1.88) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit),GO:0005737; GO:0005634; GO:0004596,cytoplasm; nucleus; peptide alpha-N-acetyltransferase activity,PF00583;,8.00E-77,CHOYP_BRAFLDRAFT_284784.1.1,,,,,,,NAA20_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),N-terminal peptidyl-methionine acetylation [GO:0017196] comp139977_c0_seq1,2010,33.7313,0.31511603,4,14,,3.00E-10,Q5U504,Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5),Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5),GO:0007275; GO:0030017,multicellular organismal development; sarcomere,PF07707;PF00651;PF01344;,,,,,,,,,KBTB5_XENLA,Xenopus laevis (African clawed frog),negative regulation of protein ubiquitination [GO:0031397]; skeletal muscle fiber development [GO:0048741] comp139977_c0_seq2,3336,35.9712,0.40986393,111,504,,7.00E-62,O95198,Kelch-like protein 2 (Actin-binding protein Mayven),Kelch-like protein 2 (Actin-binding protein Mayven),GO:0031463; GO:0003779; GO:0015629; GO:0005737; GO:0005829; GO:0030027; GO:0016567; GO:0001726,Cul3-RING ubiquitin ligase complex; actin binding; actin cytoskeleton; cytoplasm; cytosol; lamellipodium; protein ubiquitination; ruffle,PF07707;PF00651;PF01344;,4.00E-40,CHOYP_KLH20.1.2,,,,,,,KLHL2_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp139977_c2_seq2,1149,40.47,0.34190601,0,4,,7.00E-62,Q5M7T4,Protein YIPF4 (YIP1 family member 4),Protein YIPF4 (YIP1 family member 4),GO:0005794; GO:0016021,Golgi apparatus; integral to membrane,PF04893;,9.00E-100,CHOYP_EXO1.2.2,,,,,,,YIPF4_RAT,Rattus norvegicus (Rat), comp139978_c2_seq1,1212,30.7756,0.56050405,394,612,,1.00E-22,O00142,"Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)","Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)",GO:0005524; GO:0004137; GO:0046092; GO:0009262; GO:0006264; GO:0005743; GO:0005759; GO:0016773; GO:0006206; GO:0043097; GO:0004797; GO:0046104,"ATP binding; deoxycytidine kinase activity; deoxycytidine metabolic process; deoxyribonucleotide metabolic process; mitochondrial DNA replication; mitochondrial inner membrane; mitochondrial matrix; phosphotransferase activity, alcohol group as acceptor; pyrimidine nucleobase metabolic process; pyrimidine nucleoside salvage; thymidine kinase activity; thymidine metabolic process",PF01712;,,,,,,,,,KITM_HUMAN,Homo sapiens (Human),deoxycytidine metabolic process [GO:0046092]; DNA biosynthetic process [GO:0071897]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside salvage [GO:0043097]; thymidine metabolic process [GO:0046104] comp139978_c2_seq2,689,40.2032,0.50507269,134,316,,1.00E-25,Q9XZT6,Deoxynucleoside kinase (EC 2.7.1.145) (Deoxyribonucleoside kinase) (Dm-dNK) (Multispecific deoxynucleoside kinase),Deoxynucleoside kinase (EC 2.7.1.145) (Deoxyribonucleoside kinase) (Dm-dNK) (Multispecific deoxynucleoside kinase),GO:0005524; GO:0006260; GO:0005737; GO:0019136; GO:0006165; GO:0016773,"ATP binding; DNA replication; cytoplasm; deoxynucleoside kinase activity; nucleoside diphosphate phosphorylation; phosphotransferase activity, alcohol group as acceptor",PF01712;,,,,,,,,,DNK_DROME,Drosophila melanogaster (Fruit fly),DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230] comp139980_c1_seq3,2479,36.7084,0.31364771,5,0,,9.00E-06,O14727,Apoptotic protease-activating factor 1 (APAF-1),Apoptotic protease-activating factor 1 (APAF-1),GO:0043531; GO:0005524; GO:0005794; GO:0008635; GO:0043293; GO:0006309; GO:0008656; GO:0006952; GO:0030900; GO:0097193; GO:0007399; GO:0001843; GO:0051402; GO:0000166; GO:0005634,ADP binding; ATP binding; Golgi apparatus; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; apoptosome; apoptotic DNA fragmentation; cysteine-type endopeptidase activator activity involved in apoptotic process; defense response; forebrain development; intrinsic apoptotic signaling pathway; nervous system development; neural tube closure; neuron apoptotic process; nucleotide binding; nucleus,PF00619;PF00931;PF00400;,0,CHOYP_WDR92.1.1,2.00E-34,ruditapes2_c1810,,,,,APAF_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; glial cell apoptotic process [GO:0034349]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584] comp139980_c1_seq4,2441,37.1979,0.31009983,23,9,,0,Q8BGF3,WD repeat-containing protein 92 (WD repeat-containing protein Monad),WD repeat-containing protein 92 (WD repeat-containing protein Monad),GO:0006915,apoptotic process,PF00400;,,,,,,,,,WDR92_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915] comp139981_c1_seq1,2043,43.955,0.45829379,0,0,,2.00E-130,Q80UG8,Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0018095; GO:0015631,cilium; cytoplasm; ligase activity; microtubule basal body; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL4_MOUSE,Mus musculus (Mouse),peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095] comp139981_c1_seq10,1953,43.83,0.45022065,0,0,,,,,,,,,2.00E-155,CHOYP_LOC576625.1.1,,,,,,,,, comp139981_c1_seq11,2007,43.8964,0.44756851,0,0,,3.00E-126,Q14679,Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0018095; GO:0015631,cilium; cytoplasm; ligase activity; microtubule basal body; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL4_HUMAN,Homo sapiens (Human),peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095] comp139981_c1_seq14,1919,43.2517,0.43520726,0,0,,2.00E-128,Q80UG8,Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0018095; GO:0015631,cilium; cytoplasm; ligase activity; microtubule basal body; protein polyglutamylation; tubulin binding,PF03133;,,,,,,,,,TTLL4_MOUSE,Mus musculus (Mouse),peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095] comp139981_c1_seq3,2081,43.8731,0.45160088,0,0,,,,,,,,,7.00E-155,CHOYP_LOC576625.1.1,,,,,,,,, comp139981_c1_seq9,1989,43.8914,0.46125492,0,0,,9.00E-131,Q80UG8,Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4),GO:0005929; GO:0005737; GO:0016874; GO:0005932; GO:0018095; GO:0015631,cilium; cytoplasm; ligase activity; microtubule basal body; protein polyglutamylation; tubulin binding,PF03133;,2.00E-155,CHOYP_LOC576625.1.1,,,,,,,TTLL4_MOUSE,Mus musculus (Mouse),peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095] comp139982_c0_seq1,2974,39.8117,0.46861402,73,555,,0,Q8BJW6,"Eukaryotic translation initiation factor 2A (eIF-2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]","Eukaryotic translation initiation factor 2A (eIF-2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]",GO:0032933; GO:0005850; GO:0009967; GO:0006468; GO:0006417; GO:0042255; GO:0043022; GO:0000049; GO:0003743,SREBP signaling pathway; eukaryotic translation initiation factor 2 complex; positive regulation of signal transduction; protein phosphorylation; regulation of translation; ribosome assembly; ribosome binding; tRNA binding; translation initiation factor activity,PF08662;,,,,,,,,,EIF2A_MOUSE,Mus musculus (Mouse),positive regulation of signal transduction [GO:0009967]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; ribosome assembly [GO:0042255]; SREBP signaling pathway [GO:0032933]; translation [GO:0006412] comp139982_c0_seq2,2985,39.8995,0.46476686,70,1099,,0,Q7ZY11,Eukaryotic translation initiation factor 2A (eIF-2A),Eukaryotic translation initiation factor 2A (eIF-2A),GO:0006417; GO:0003743,regulation of translation; translation initiation factor activity,PF08662;,6.00E-88,CHOYP_EIF2A.1.1,,,,,,,EIF2A_XENLA,Xenopus laevis (African clawed frog),regulation of translation [GO:0006417] comp139983_c0_seq1,2243,37.539,0.50698985,164,681,,,,,,,,,1.00E-12,CHOYP_RNP1B.1.1,,,,,,,,, comp139983_c0_seq2,2216,37.9061,0.51613482,263,795,,5.00E-29,Q6PG31,RNA-binding protein with serine-rich domain 1,RNA-binding protein with serine-rich domain 1,GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0016607; GO:0000166,RNA binding; RNA splicing; cytoplasm; mRNA processing; nuclear speck; nucleotide binding,PF00076;,1.00E-12,CHOYP_RNP1B.1.1,,,,,,,RNPS1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp139988_c0_seq1,1216,38.4868,0.37828227,268,2304,,2.00E-38,Q178L7,"Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (Succinate dehydrogenase subunit 5, mitochondrial)","Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2)",GO:0006121; GO:0005739; GO:0018293,"mitochondrial electron transport, succinate to ubiquinone; mitochondrion; protein-FAD linkage",PF03937;,1.00E-23,CHOYP_SDHF2.1.1,,,,,,,SDHF2_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; protein-FAD linkage [GO:0018293]" comp139989_c0_seq1,1180,42.1186,0.34577123,103,708,,1.00E-117,Q8AVP1,Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1),Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1),GO:0003723; GO:0005730; GO:0019843; GO:0006364,RNA binding; nucleolus; rRNA binding; rRNA processing,PF04427;,1.00E-105,CHOYP_LOC100374993.1.1,1.00E-89,ruditapes_c13386,,,,,RPF1_XENLA,Xenopus laevis (African clawed frog),rRNA processing [GO:0006364] comp139992_c0_seq1,2149,38.5761,0.59328859,794,704,,1.00E-76,P20695,Interferon-related developmental regulator 1 (IRPR) (Nerve growth factor-inducible protein PC4),Interferon-related developmental regulator 1 (IRPR) (Nerve growth factor-inducible protein PC4),GO:0005737; GO:0014009; GO:0042692; GO:0007405; GO:0005634; GO:0005886,cytoplasm; glial cell proliferation; muscle cell differentiation; neuroblast proliferation; nucleus; plasma membrane,PF05004;PF04836;,4.00E-57,CHOYP_BRAFLDRAFT_113696.1.1,,,,,,,IFRD1_RAT,Rattus norvegicus (Rat),glial cell proliferation [GO:0014009]; muscle cell differentiation [GO:0042692]; neuroblast proliferation [GO:0007405]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp139994_c0_seq1,1589,48.584,0.42418289,0,0,,0,Q64514,Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II),Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II),GO:0004177; GO:0005737; GO:0005634; GO:0006508; GO:0004252,aminopeptidase activity; cytoplasm; nucleus; proteolysis; serine-type endopeptidase activity,PF00082;PF12580;,,,,,,,,,TPP2_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp139994_c0_seq2,4086,43.49,0.49347733,0,0,,0,Q64560,Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II),Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II),GO:0004177; GO:0005737; GO:0005634; GO:0042277; GO:0006508; GO:0004252; GO:0008240,aminopeptidase activity; cytoplasm; nucleus; peptide binding; proteolysis; serine-type endopeptidase activity; tripeptidyl-peptidase activity,PF00082;PF12580;,,,,,,,,,TPP2_RAT,Rattus norvegicus (Rat),proteolysis [GO:0006508] comp139994_c0_seq3,4023,43.4999,0.48487002,0,0,,1.00E-33,P72186,Pyrolysin (EC 3.4.21.-),Pyrolysin (EC 3.4.21.-),GO:0031975; GO:0006508; GO:0004252,envelope; proteolysis; serine-type endopeptidase activity,PF00082;PF04151;,2.00E-145,CHOYP_TPP2.1.1,,,,,,,PLS_PYRFU,Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1), comp139994_c0_seq5,4035,43.4449,0.48456497,0,0,,0,Q64560,Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II),Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II),GO:0004177; GO:0005737; GO:0005634; GO:0042277; GO:0006508; GO:0004252; GO:0008240,aminopeptidase activity; cytoplasm; nucleus; peptide binding; proteolysis; serine-type endopeptidase activity; tripeptidyl-peptidase activity,PF00082;PF12580;,2.00E-145,CHOYP_TPP2.1.1,,,,,,,TPP2_RAT,Rattus norvegicus (Rat),proteolysis [GO:0006508] comp139995_c0_seq1,2789,39.7992,0.44980906,5809,40510,,0,Q4G061,Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (eIF-3-eta),Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (eIF-3-eta),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0000166; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; nucleotide binding; regulation of translational initiation; translation initiation factor activity; translational initiation,PF08662;PF00076;,0,CHOYP_EIF3B.1.1,,,,,,,EIF3B_RAT,Rattus norvegicus (Rat),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp139996_c0_seq1,1606,42.0299,0.54115644,15,60,,8.00E-98,Q90X38,G patch domain and KOW motifs-containing protein (Protein T54-like),G patch domain and KOW motifs-containing protein (Protein T54-like),GO:0003676; GO:0005634,nucleic acid binding; nucleus,PF12656;PF00467;,1.00E-35,CHOYP_LOC575416.1.1,,,,,,,GPKOW_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139996_c0_seq2,666,40.5405,0.67673903,0,8,,4.00E-11,Q9C801,Protein MOS2,Protein MOS2,GO:0003723; GO:0009870; GO:0042742; GO:0005634,"RNA binding; defense response signaling pathway, resistance gene-dependent; defense response to bacterium; nucleus",PF12656;,,,,,,,,,MOS2_ARATH,Arabidopsis thaliana (Mouse-ear cress),"defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response to bacterium [GO:0042742]" comp139996_c0_seq3,1879,41.884,0.54897084,0,0,,8.00E-97,Q90X38,G patch domain and KOW motifs-containing protein (Protein T54-like),G patch domain and KOW motifs-containing protein (Protein T54-like),GO:0003676; GO:0005634,nucleic acid binding; nucleus,PF12656;PF00467;,,,,,,,,,GPKOW_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp139997_c2_seq1,2427,34.8578,0.50948241,153,1409,,2.00E-172,P49137,MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1),MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1),GO:0070935; GO:0005524; GO:0031572; GO:0002755; GO:0007265; GO:0035666; GO:0000187; GO:0019369; GO:0035924; GO:0005829; GO:0010467; GO:0006954; GO:0045087; GO:0048839; GO:0006691; GO:0016071; GO:0044351; GO:0048011; GO:0005654; GO:0018105; GO:0004674; GO:0032675; GO:0032680; GO:0034097; GO:0032496; GO:0004871; GO:0051403; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124; GO:0048010,3'-UTR-mediated mRNA stabilization; ATP binding; G2 DNA damage checkpoint; MyD88-dependent toll-like receptor signaling pathway; Ras protein signal transduction; TRIF-dependent toll-like receptor signaling pathway; activation of MAPK activity; arachidonic acid metabolic process; cellular response to vascular endothelial growth factor stimulus; cytosol; gene expression; inflammatory response; innate immune response; inner ear development; leukotriene metabolic process; mRNA metabolic process; macropinocytosis; neurotrophin TRK receptor signaling pathway; nucleoplasm; peptidyl-serine phosphorylation; protein serine/threonine kinase activity; regulation of interleukin-6 production; regulation of tumor necrosis factor production; response to cytokine stimulus; response to lipopolysaccharide; signal transducer activity; stress-activated MAPK cascade; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway; vascular endothelial growth factor receptor signaling pathway,PF00069;,7.00E-175,CHOYP_LOC100368658.1.1,,,,,,,MAPK2_HUMAN,Homo sapiens (Human),3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of MAPK activity [GO:0000187]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; G2 DNA damage checkpoint [GO:0031572]; inflammatory response [GO:0006954]; inner ear development [GO:0048839]; leukotriene metabolic process [GO:0006691]; macropinocytosis [GO:0044351]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of cellular response to heat [GO:1900034]; regulation of interleukin-6 production [GO:0032675]; regulation of mRNA stability [GO:0043488]; regulation of tumor necrosis factor production [GO:0032680]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; response to stress [GO:0006950]; toll-like receptor signaling pathway [GO:0002224]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp139998_c0_seq1,1920,43.6979,0.48708594,288,918,,0,A6QPU5,"Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)","Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)",GO:0005524; GO:0004815; GO:0005759; GO:0003676; GO:0006418,ATP binding; aspartate-tRNA ligase activity; mitochondrial matrix; nucleic acid binding; tRNA aminoacylation for protein translation,PF02938;PF00152;PF01336;,3.00E-45,CHOYP_DARS2.1.1,,,,,,,SYDM_BOVIN,Bos taurus (Bovine),mitochondrial asparaginyl-tRNA aminoacylation [GO:0070145] comp139999_c0_seq1,1782,44.3322,0.77358613,5,0,,0,Q8K4C0,Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),GO:0004499; GO:0050661; GO:0005789; GO:0050660; GO:0016021,"N,N-dimethylaniline monooxygenase activity; NADP binding; endoplasmic reticulum membrane; flavin adenine dinucleotide binding; integral to membrane",PF00743;,1.00E-56,CHOYP_FMO5.5.6,,,,,,,FMO5_RAT,Rattus norvegicus (Rat),drug metabolic process [GO:0017144] comp139999_c0_seq2,1838,44.0696,0.75896267,2,17,,0,Q8K4C0,Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),GO:0004499; GO:0050661; GO:0005789; GO:0050660; GO:0016021,"N,N-dimethylaniline monooxygenase activity; NADP binding; endoplasmic reticulum membrane; flavin adenine dinucleotide binding; integral to membrane",PF00743;,2.00E-84,CHOYP_FMO5.4.6,,,,,,,FMO5_RAT,Rattus norvegicus (Rat),drug metabolic process [GO:0017144] comp140000_c0_seq1,920,46.6304,0.64114242,0,0,,3.00E-12,Q99963,Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),GO:0007417; GO:0031901; GO:0006897; GO:0008289; GO:0007165,central nervous system development; early endosome membrane; endocytosis; lipid binding; signal transduction,PF03114;PF07653;,,,,,,,,,SH3G3_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165] comp140000_c0_seq10,5691,41.7326,0.52495965,0,0,,1.00E-10,Q62420,Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4),Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4),GO:0005737; GO:0008289; GO:0016020; GO:0002090; GO:0048488,cytoplasm; lipid binding; membrane; regulation of receptor internalization; synaptic vesicle endocytosis,PF03114;PF00018;,3.00E-83,CHOYP_LOC100867381.6.8,,,,,,,SH3G2_MOUSE,Mus musculus (Mouse),regulation of receptor internalization [GO:0002090]; synaptic vesicle endocytosis [GO:0048488] comp140000_c0_seq12,4631,43.5327,0.48867747,0,0,,1.00E-40,Q9BX66,Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),GO:0005070; GO:0003779; GO:0005813; GO:0005829; GO:0005925; GO:0048041; GO:0015758; GO:0005158; GO:0008286; GO:0045121; GO:0006936; GO:0016363; GO:0005634; GO:0005886; GO:0090004; GO:0046326; GO:0045725; GO:0046889; GO:0001725; GO:0043149; GO:0005915,SH3/SH2 adaptor activity; actin binding; centrosome; cytosol; focal adhesion; focal adhesion assembly; glucose transport; insulin receptor binding; insulin receptor signaling pathway; membrane raft; muscle contraction; nuclear matrix; nucleus; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; stress fiber; stress fiber assembly; zonula adherens,PF00018;PF07653;PF14604;PF02208;,1.00E-98,CHOYP_LOC100867381.4.8,,,,,,,SRBS1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149] comp140000_c0_seq13,5274,41.3349,0.52064881,0,0,,2.00E-40,Q9BX66,Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),GO:0005070; GO:0003779; GO:0005813; GO:0005829; GO:0005925; GO:0048041; GO:0015758; GO:0005158; GO:0008286; GO:0045121; GO:0006936; GO:0016363; GO:0005634; GO:0005886; GO:0090004; GO:0046326; GO:0045725; GO:0046889; GO:0001725; GO:0043149; GO:0005915,SH3/SH2 adaptor activity; actin binding; centrosome; cytosol; focal adhesion; focal adhesion assembly; glucose transport; insulin receptor binding; insulin receptor signaling pathway; membrane raft; muscle contraction; nuclear matrix; nucleus; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; stress fiber; stress fiber assembly; zonula adherens,PF00018;PF07653;PF14604;PF02208;,2.00E-83,CHOYP_LOC100867381.6.8,,,,,,,SRBS1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149] comp140000_c0_seq14,1685,47.5964,0.51392225,0,0,,,,,,,,,5.00E-23,CHOYP_PDLI2.2.3,,,,,,,,, comp140000_c0_seq15,1159,45.2114,0.64854097,0,0,,2.00E-11,Q99963,Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),GO:0007417; GO:0031901; GO:0006897; GO:0008289; GO:0007165,central nervous system development; early endosome membrane; endocytosis; lipid binding; signal transduction,PF03114;PF07653;,,,,,,,,,SH3G3_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165] comp140000_c0_seq16,1183,45.4776,0.62595868,0,0,,8.00E-12,Q99962,Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2),Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2),GO:0000139; GO:0019886; GO:0007411; GO:0007417; GO:0030669; GO:0005829; GO:0007173; GO:0008289; GO:0042059; GO:0048011; GO:0005886; GO:0006892; GO:0002090; GO:0048488,Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; central nervous system development; clathrin-coated endocytic vesicle membrane; cytosol; epidermal growth factor receptor signaling pathway; lipid binding; negative regulation of epidermal growth factor receptor signaling pathway; neurotrophin TRK receptor signaling pathway; plasma membrane; post-Golgi vesicle-mediated transport; regulation of receptor internalization; synaptic vesicle endocytosis,PF03114;PF07653;,,,,,,,,,SH3G2_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; central nervous system development [GO:0007417]; microtubule-based movement [GO:0007018]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; regulation of receptor internalization [GO:0002090]; signal transduction [GO:0007165]; synaptic vesicle endocytosis [GO:0048488] comp140000_c0_seq18,5298,41.4119,0.51617721,0,0,,2.00E-14,Q3SX40,PDZ and LIM domain protein 7,PDZ and LIM domain protein 7,GO:0030154; GO:0005737; GO:0005856; GO:0007275; GO:0001503; GO:0008270,cell differentiation; cytoplasm; cytoskeleton; multicellular organismal development; ossification; zinc ion binding,PF00412;PF00595;,5.00E-86,CHOYP_LOC100867381.4.8,,,,,,,PDLI7_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503] comp140000_c0_seq2,5640,41.7199,0.52998144,1,6,,2.00E-34,O35413,Sorbin and SH3 domain-containing protein 2 (Arg/Abl-interacting protein 2) (ArgBP2) (Neural ArgBP2) (nArgBP2) (Sorbin),Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Neural ArgBP2) (nArgBP2) (Sorbin),GO:0030425; GO:0046872; GO:0043025; GO:0048471; GO:0014069,dendrite; metal ion binding; neuronal cell body; perinuclear region of cytoplasm; postsynaptic density,PF00018;PF14604;PF02208;,2.00E-22,CHOYP_PDLI2.2.3,,,,,,,SRBS2_RAT,Rattus norvegicus (Rat),actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell migration [GO:0016477] comp140000_c0_seq4,5667,41.6623,0.52904721,0,0,,8.00E-39,Q62417,Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),GO:0005913; GO:0005924; GO:0005829; GO:0005925; GO:0048041; GO:0015758; GO:0005158; GO:0008286; GO:0045121; GO:0016363; GO:0005886; GO:0090004; GO:0046326; GO:0045725; GO:0046889; GO:0019901; GO:0001725; GO:0043149,cell-cell adherens junction; cell-substrate adherens junction; cytosol; focal adhesion; focal adhesion assembly; glucose transport; insulin receptor binding; insulin receptor signaling pathway; membrane raft; nuclear matrix; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; protein kinase binding; stress fiber; stress fiber assembly,PF00018;PF07653;PF14604;PF02208;,3.00E-89,CHOYP_LOC100867381.4.8,,,,,,,SRBS1_MOUSE,Mus musculus (Mouse),cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149] comp140000_c0_seq6,5616,41.6132,0.53507392,0,0,,7.00E-39,Q62417,Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),GO:0005913; GO:0005924; GO:0005829; GO:0005925; GO:0048041; GO:0015758; GO:0005158; GO:0008286; GO:0045121; GO:0016363; GO:0005886; GO:0090004; GO:0046326; GO:0045725; GO:0046889; GO:0019901; GO:0001725; GO:0043149,cell-cell adherens junction; cell-substrate adherens junction; cytosol; focal adhesion; focal adhesion assembly; glucose transport; insulin receptor binding; insulin receptor signaling pathway; membrane raft; nuclear matrix; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; protein kinase binding; stress fiber; stress fiber assembly,PF00018;PF07653;PF14604;PF02208;,3.00E-83,CHOYP_LOC100867381.6.8,,,,,,,SRBS1_MOUSE,Mus musculus (Mouse),cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149] comp140000_c0_seq7,1525,45.7049,0.64085996,0,0,,9.00E-12,Q99963,Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),GO:0007417; GO:0031901; GO:0006897; GO:0008289; GO:0007165,central nervous system development; early endosome membrane; endocytosis; lipid binding; signal transduction,PF03114;PF07653;,,,,,,,,,SH3G3_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165] comp140000_c0_seq8,4655,43.609,0.48429094,0,0,,1.00E-39,Q9BX66,Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP),GO:0005070; GO:0003779; GO:0005813; GO:0005829; GO:0005925; GO:0048041; GO:0015758; GO:0005158; GO:0008286; GO:0045121; GO:0006936; GO:0016363; GO:0005634; GO:0005886; GO:0090004; GO:0046326; GO:0045725; GO:0046889; GO:0001725; GO:0043149; GO:0005915,SH3/SH2 adaptor activity; actin binding; centrosome; cytosol; focal adhesion; focal adhesion assembly; glucose transport; insulin receptor binding; insulin receptor signaling pathway; membrane raft; muscle contraction; nuclear matrix; nucleus; plasma membrane; positive regulation of establishment of protein localization to plasma membrane; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; stress fiber; stress fiber assembly; zonula adherens,PF00018;PF07653;PF14604;PF02208;,4.00E-86,CHOYP_LOC100867381.4.8,,,,,,,SRBS1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149] comp140000_c0_seq9,1501,45.503,0.65684034,0,0,,9.00E-12,Q99963,Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3),GO:0007417; GO:0031901; GO:0006897; GO:0008289; GO:0007165,central nervous system development; early endosome membrane; endocytosis; lipid binding; signal transduction,PF03114;PF07653;,,,,,,,,,SH3G3_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165] comp140003_c1_seq1,3348,35.3345,0.71946007,2818,756,,2.00E-06,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp140004_c0_seq1,1497,36.8737,0.39769049,1,10,,4.00E-68,Q9EQ15,Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF),Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF),GO:0005737; GO:0035176,cytoplasm; social behavior,PF00400;,,,,,,,,,GNB1L_MOUSE,Mus musculus (Mouse),social behavior [GO:0035176] comp140004_c0_seq2,1509,36.6468,0.35906801,0,2,,4.00E-10,Q00808,Vegetative incompatibility protein HET-E-1,Vegetative incompatibility protein HET-E-1,GO:0005525,GTP binding,PF06985;PF00400;,,,,,,,,,HETE1_PODAS,Podospora anserina (Pleurage anserina), comp140004_c0_seq3,649,41.1402,0.40473321,0,0,,3.00E-09,Q6CFV3,ASTRA-associated protein 1,ASTRA-associated protein 1,GO:0016568; GO:0005634,chromatin modification; nucleus,PF00400;,,,,,,,,,ASA1_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),chromatin remodeling [GO:0006338] comp140004_c0_seq5,661,40.6959,0.44236653,0,4,,2.00E-07,C9STX5,ASTRA-associated protein 1,ASTRA-associated protein 1,GO:0016568; GO:0005634,chromatin modification; nucleus,PF00400;,,,,,,,,,ASA1_VERA1,Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) (Verticillium wilt of alfalfa) (Verticillium albo-atrum),chromatin remodeling [GO:0006338] comp140004_c0_seq6,485,35.6701,0.26087067,16,28,,3.00E-28,Q9EQ15,Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF),Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF),GO:0005737; GO:0035176,cytoplasm; social behavior,PF00400;,,,,,,,,,GNB1L_MOUSE,Mus musculus (Mouse),social behavior [GO:0035176] comp140005_c2_seq1,1774,42.1646,0.48493099,0,0,,,,,,,,,7.00E-47,CHOYP_BCAT1.1.1,,,,,,,,, comp140005_c2_seq3,1710,41.9298,0.48231165,0,0,,4.00E-146,A7SLW1,Branched-chain-amino-acid aminotransferase (EC 2.6.1.42),Branched-chain-amino-acid aminotransferase (EC 2.6.1.42),GO:0052656; GO:0052654; GO:0052655; GO:0009082,L-isoleucine transaminase activity; L-leucine transaminase activity; L-valine transaminase activity; branched-chain amino acid biosynthetic process,PF01063;,,,,,,,,,BCAT_NEMVE,Nematostella vectensis (Starlet sea anemone),aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099] comp140005_c2_seq4,1748,41.762,0.47541185,0,0,,7.00E-134,O15382,"Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18)","Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18)",GO:0052656; GO:0052654; GO:0052655; GO:0009082; GO:0009083; GO:0004084; GO:0034641; GO:0006550; GO:0006551; GO:0005759; GO:0010817; GO:0006573,L-isoleucine transaminase activity; L-leucine transaminase activity; L-valine transaminase activity; branched-chain amino acid biosynthetic process; branched-chain amino acid catabolic process; branched-chain-amino-acid transaminase activity; cellular nitrogen compound metabolic process; isoleucine catabolic process; leucine metabolic process; mitochondrial matrix; regulation of hormone levels; valine metabolic process,PF01063;,,,,,,,,,BCAT2_HUMAN,Homo sapiens (Human),aspartate biosynthetic process [GO:0006532]; branched-chain amino acid biosynthetic process [GO:0009082]; branched-chain amino acid catabolic process [GO:0009083]; leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099] comp140005_c2_seq7,1736,42.3387,0.49168694,0,0,,,,,,,,,6.00E-47,CHOYP_BCAT1.1.1,,,,,,,,, comp140005_c4_seq3,1657,41.6415,0.41372976,78,27,,5.00E-45,Q4R4Q3,Protein NDRG1 (N-myc downstream-regulated gene 1 protein),Protein NDRG1 (N-myc downstream-regulated gene 1 protein),GO:0005829; GO:0005874; GO:0005815; GO:0005634; GO:0005886,cytosol; microtubule; microtubule organizing center; nucleus; plasma membrane,PF03096;,,,,,,,,,NDRG1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),mast cell activation [GO:0045576]; peripheral nervous system myelin maintenance [GO:0032287]; regulation of cell proliferation [GO:0042127] comp140005_c4_seq4,1411,43.9405,0.37453202,2,16,,5.00E-77,O02485,Uncharacterized protein ZK1073.1,Uncharacterized protein ZK1073.1,,,PF03096;,9.00E-101,CHOYP_SMP_194720.1.1,,,1.00E-90,AM858990.p.cg.6,6,,YDJ1_CAEEL,Caenorhabditis elegans,signal transduction [GO:0007165] comp140007_c0_seq1,2017,38.6217,0.52263141,1125,2636,,1.00E-78,Q3ZBX6,"39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3)","39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF00297;,,,,,,,,,RM03_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp140009_c1_seq2,3603,41.7985,0.57021266,70,31,,3.00E-102,O76373,Cytosolic carboxypeptidase 1 (EC 3.4.17.-),Cytosolic carboxypeptidase 1 (EC 3.4.17.-),GO:0005737; GO:0004181; GO:0006508; GO:0008270,cytoplasm; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,0,CHOYP_CBPC1.1.1,,,,,,,CBPC1_CAEEL,Caenorhabditis elegans, comp140009_c1_seq4,2917,43.675,0.55650617,25,0,,0,A9JRL3,Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (ATP/GTP-binding protein 1),Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (ATP/GTP-binding protein 1),GO:0035609; GO:0021702; GO:0005829; GO:0001754; GO:0004181; GO:0005739; GO:0007005; GO:0050905; GO:0021772; GO:0035610; GO:0006508; GO:0015631; GO:0008270,C-terminal protein deglutamylation; cerebellar Purkinje cell differentiation; cytosol; eye photoreceptor cell differentiation; metallocarboxypeptidase activity; mitochondrion; mitochondrion organization; neuromuscular process; olfactory bulb development; protein side chain deglutamylation; proteolysis; tubulin binding; zinc ion binding,PF00246;,0,CHOYP_CBPC1.1.1,,,,,,,CBPC1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cerebellar Purkinje cell differentiation [GO:0021702]; chordate embryonic development [GO:0043009]; C-terminal protein deglutamylation [GO:0035609]; eye photoreceptor cell differentiation [GO:0001754]; mitochondrion organization [GO:0007005]; neuromuscular process [GO:0050905]; olfactory bulb development [GO:0021772]; protein side chain deglutamylation [GO:0035610] comp140015_c0_seq1,829,41.0133,0.41412798,33,161,,1.00E-26,A1L2T6,Zinc finger CCHC domain-containing protein 7,Zinc finger CCHC domain-containing protein 7 (TRAMP-like complex RNA-binding factor ZCCHC7),GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,PF00098;,,,,,,,,,ZCHC7_XENLA,Xenopus laevis (African clawed frog), comp140017_c0_seq2,1790,39.6089,0.64462424,73,84,,5.00E-93,Q6QHF9,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase),Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase),GO:0052899; GO:0052904; GO:0052903; GO:0005782; GO:0006598; GO:0046592; GO:1901307; GO:0009446; GO:0009447; GO:0044281; GO:0046203; GO:0052902; GO:0046208; GO:0052901; GO:0006805,"N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; peroxisomal matrix; polyamine catabolic process; polyamine oxidase activity; positive regulation of spermidine biosynthetic process; putrescine biosynthetic process; putrescine catabolic process; small molecule metabolic process; spermidine catabolic process; spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity; spermine catabolic process; spermine:oxygen oxidoreductase (spermidine-forming) activity; xenobiotic metabolic process",PF01593;,6.00E-35,CHOYP_SMOX.1.2,,,,,,,PAOX_HUMAN,Homo sapiens (Human),polyamine biosynthetic process [GO:0006596]; polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208] comp140017_c0_seq4,1272,38.522,0.77212121,0,6,,2.00E-57,Q6QHF9,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase),Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase),GO:0052899; GO:0052904; GO:0052903; GO:0005782; GO:0006598; GO:0046592; GO:1901307; GO:0009446; GO:0009447; GO:0044281; GO:0046203; GO:0052902; GO:0046208; GO:0052901; GO:0006805,"N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; peroxisomal matrix; polyamine catabolic process; polyamine oxidase activity; positive regulation of spermidine biosynthetic process; putrescine biosynthetic process; putrescine catabolic process; small molecule metabolic process; spermidine catabolic process; spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity; spermine catabolic process; spermine:oxygen oxidoreductase (spermidine-forming) activity; xenobiotic metabolic process",PF01593;,1.00E-17,CHOYP_SMOX.1.2,,,,,,,PAOX_HUMAN,Homo sapiens (Human),polyamine biosynthetic process [GO:0006596]; polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208] comp140020_c0_seq1,1658,44.5115,0.48894801,11,94,,2.00E-42,Q2PFV2,Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],GO:0006915; GO:0004197; GO:0005737; GO:0006508,apoptotic process; cysteine-type endopeptidase activity; cytoplasm; proteolysis,,,,,,,,,,CASP3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),apoptotic process [GO:0006915] comp140020_c0_seq3,1676,44.5704,0.4821669,29,120,,9.00E-41,Q2PFV2,Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],GO:0006915; GO:0004197; GO:0005737; GO:0006508,apoptotic process; cysteine-type endopeptidase activity; cytoplasm; proteolysis,,,,,,,,,,CASP3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),apoptotic process [GO:0006915] comp140021_c1_seq1,1029,38.1924,0.67005007,10,42,,9.00E-43,Q8LGU7,Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase NUZ) (tRNA 3 endonuclease) (tRNase Z),Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase NUZ) (tRNA 3 endonuclease) (tRNase Z),GO:0042781; GO:0046872; GO:0005634; GO:0042780,3'-tRNA processing endoribonuclease activity; metal ion binding; nucleus; tRNA 3'-end processing,PF12706;,,,,,,,,,RNZN_ARATH,Arabidopsis thaliana (Mouse-ear cress),tRNA 3'-end processing [GO:0042780]; tRNA processing [GO:0008033] comp140022_c0_seq4,2687,39.2259,0.55411864,0,0,,0,Q6GN29,Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2),Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2),GO:0005525; GO:0006184; GO:0003924; GO:0007030; GO:0005783; GO:0005789; GO:0007029; GO:0042802; GO:0016021; GO:0051260,GTP binding; GTP catabolic process; GTPase activity; Golgi organization; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum organization; identical protein binding; integral to membrane; protein homooligomerization,PF02263;PF02841;,,,,,,,,,ATLA2_XENLA,Xenopus laevis (African clawed frog),endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260] comp140022_c0_seq5,2633,39.4227,0.56023322,0,0,,0,Q6PA06,Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2),Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2),GO:0005525; GO:0006184; GO:0003924; GO:0007030; GO:0005783; GO:0005789; GO:0007029; GO:0042802; GO:0016021; GO:0051260,GTP binding; GTP catabolic process; GTPase activity; Golgi organization; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum organization; identical protein binding; integral to membrane; protein homooligomerization,PF02263;,5.00E-177,CHOYP_LOC100374960.1.1,,,,,,,ATLA2_MOUSE,Mus musculus (Mouse),endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260] comp140022_c0_seq6,1287,42.6573,0.43233109,0,4,,0,Q6PA06,Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2),Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2),GO:0005525; GO:0006184; GO:0003924; GO:0007030; GO:0005783; GO:0005789; GO:0007029; GO:0042802; GO:0016021; GO:0051260,GTP binding; GTP catabolic process; GTPase activity; Golgi organization; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum organization; identical protein binding; integral to membrane; protein homooligomerization,PF02263;,6.00E-160,CHOYP_LOC100374960.1.1,,,,,,,ATLA2_MOUSE,Mus musculus (Mouse),endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260] comp140026_c1_seq1,4577,39.7859,0.45775536,3769,7067,,0,Q96J94,Piwi-like protein 1,Piwi-like protein 1,GO:0043186; GO:0033391; GO:0031047; GO:0003729; GO:0005845; GO:0007126; GO:0007275; GO:0034584; GO:0034587; GO:0005844; GO:0006417; GO:0003727; GO:0007286,P granule; chromatoid body; gene silencing by RNA; mRNA binding; mRNA cap binding complex; meiosis; multicellular organismal development; piRNA binding; piRNA metabolic process; polysome; regulation of translation; single-stranded RNA binding; spermatid development,PF08699;PF05831;PF02170;PF02171;,0,CHOYP_BRAFLDRAFT_126411.1.1,,,,,,,PIWL1_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; spermatid development [GO:0007286] comp140026_c1_seq3,1164,46.134,0.4565945,0,5,,3.00E-87,A6N7Y9,Piwi-like protein 1,Piwi-like protein 1,GO:0003677; GO:0043186; GO:0033391; GO:0031047; GO:0003729; GO:0005845; GO:0007126; GO:0007275; GO:0034584; GO:0034587; GO:0005844; GO:0006417; GO:0003727; GO:0007286,DNA binding; P granule; chromatoid body; gene silencing by RNA; mRNA binding; mRNA cap binding complex; meiosis; multicellular organismal development; piRNA binding; piRNA metabolic process; polysome; regulation of translation; single-stranded RNA binding; spermatid development,PF08699;PF05831;PF02170;PF02171;,7.00E-57,CHOYP_BRAFLDRAFT_126411.1.1,,,,,,,PIWL1_CHICK,Gallus gallus (Chicken),gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; spermatid development [GO:0007286] comp140028_c0_seq1,1450,37.5172,0.35350025,82,378,,4.00E-16,Q5R4I3,UBX domain-containing protein 4 (UBX domain-containing protein 2),UBX domain-containing protein 4 (UBX domain-containing protein 2),GO:0005789; GO:0005635; GO:0006986,endoplasmic reticulum membrane; nuclear envelope; response to unfolded protein,PF00789;,4.00E-23,CHOYP_UBXN4.1.1,,,,,,,UBXN4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; response to unfolded protein [GO:0006986] comp140028_c2_seq4,2326,38.3061,0.40031181,11,85,,2.00E-114,A2AQ19,RNA polymerase-associated protein RTF1 homolog,RNA polymerase-associated protein RTF1 homolog,GO:0016593; GO:0006352; GO:0016055; GO:0001711; GO:0080182; GO:0000122; GO:0005730; GO:0051571; GO:0032968; GO:0045944; GO:0003697; GO:0019827,"Cdc73/Paf1 complex; DNA-dependent transcription, initiation; Wnt receptor signaling pathway; endodermal cell fate commitment; histone H3-K4 trimethylation; negative regulation of transcription from RNA polymerase II promoter; nucleolus; positive regulation of histone H3-K4 methylation; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; single-stranded DNA binding; stem cell maintenance",PF03126;,6.00E-55,CHOYP_RTF1.1.1,,,,,,,RTF1_MOUSE,Mus musculus (Mouse),blastocyst growth [GO:0001832]; endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; stem cell population maintenance [GO:0019827]; transcription elongation from RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055] comp140028_c3_seq1,871,40.8726,0.44819138,63,270,,1.00E-12,A2AQ19,RNA polymerase-associated protein RTF1 homolog,RNA polymerase-associated protein RTF1 homolog,GO:0016593; GO:0006352; GO:0016055; GO:0001711; GO:0080182; GO:0000122; GO:0005730; GO:0051571; GO:0032968; GO:0045944; GO:0003697; GO:0019827,"Cdc73/Paf1 complex; DNA-dependent transcription, initiation; Wnt receptor signaling pathway; endodermal cell fate commitment; histone H3-K4 trimethylation; negative regulation of transcription from RNA polymerase II promoter; nucleolus; positive regulation of histone H3-K4 methylation; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; single-stranded DNA binding; stem cell maintenance",PF03126;,2.00E-18,CHOYP_RTF1.1.1,8.00E-59,ruditapes_c24165,,,,,RTF1_MOUSE,Mus musculus (Mouse),blastocyst growth [GO:0001832]; endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; stem cell population maintenance [GO:0019827]; transcription elongation from RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055] comp140032_c0_seq1,4102,46.6114,0.60823115,19,12,,0,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,0,CHOYP_KALRN.1.2,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq10,2354,45.7944,0.660802,0,0,,3.00E-63,O15068,Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein),Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein),GO:0005545; GO:0005089; GO:0007266; GO:0097190; GO:0005829; GO:0030027; GO:0048011; GO:0005886; GO:0043065; GO:0045944; GO:0035023; GO:0051056; GO:0007264,1-phosphatidylinositol binding; Rho guanyl-nucleotide exchange factor activity; Rho protein signal transduction; apoptotic signaling pathway; cytosol; lamellipodium; neurotrophin TRK receptor signaling pathway; plasma membrane; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF13716;PF00169;PF00621;PF07653;PF00435;,,,,,,,,,MCF2L_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp140032_c0_seq14,605,41.9835,0.92021764,0,0,,2.00E-71,Q6P720,Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT),Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT),GO:0005089; GO:0030016; GO:0005886; GO:0035023; GO:0030017,Rho guanyl-nucleotide exchange factor activity; myofibril; plasma membrane; regulation of Rho protein signal transduction; sarcomere,PF00621;,,,,,,,,,ARHGP_RAT,Rattus norvegicus (Rat),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq17,1960,40.1531,0.84179787,21,31,,6.00E-84,Q86VW2,Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF),Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF),GO:0005089; GO:0005829; GO:0030016; GO:0005543; GO:0005886; GO:0035023; GO:0030017,Rho guanyl-nucleotide exchange factor activity; cytosol; myofibril; phospholipid binding; plasma membrane; regulation of Rho protein signal transduction; sarcomere,PF00621;,,,,,,,,,ARHGP_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq18,1194,45.6449,0.6783904,0,0,,3.00E-57,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,,,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq19,883,42.5821,0.70754457,0,0,,4.00E-39,Q86VW2,Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF),Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF),GO:0005089; GO:0005829; GO:0030016; GO:0005543; GO:0005886; GO:0035023; GO:0030017,Rho guanyl-nucleotide exchange factor activity; cytosol; myofibril; phospholipid binding; plasma membrane; regulation of Rho protein signal transduction; sarcomere,PF00621;,,,,,,,,,ARHGP_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq2,4018,46.4659,0.62103035,0,10,,3.00E-59,Q63406,Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) (OST oncogene),Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) (OST oncogene),GO:0005089; GO:0005737; GO:0035556; GO:0005543; GO:0005886; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cytoplasm; intracellular signal transduction; phospholipid binding; plasma membrane; regulation of Rho protein signal transduction,PF13716;PF00169;PF00621;PF00435;,0,CHOYP_KALRN.1.2,,,,,,,MCF2L_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025] comp140032_c0_seq4,1215,38.1893,0.82909147,8,0,,,,,,,,,,,6.00E-24,ruditapes_c14938,,,,,,, comp140032_c0_seq5,1514,46.8956,0.67579545,8,0,,6.00E-51,Q96PX9,Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B),Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,,,,,,,,,PKH4B_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq6,2438,46.0623,0.6604998,0,0,,8.00E-58,P10911,Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein],Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein],GO:0005089; GO:0097190; GO:0005856; GO:0005829; GO:0016358; GO:0016020; GO:0048011; GO:0005543; GO:0043065; GO:0035023; GO:0051056; GO:0007264,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; cytoskeleton; cytosol; dendrite development; membrane; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF13716;PF00169;PF00621;,,,,,,,,,MCF2_HUMAN,Homo sapiens (Human),dendrite development [GO:0016358]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp140032_c0_seq7,3831,46.2542,0.63290137,0,4,,0,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,3.00E-48,CHOYP_PHUM_PHUM149600.1.1,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp140032_c0_seq8,3915,46.4112,0.62367998,0,0,,3.00E-12,P07751,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)",GO:0051693; GO:0005509; GO:0005938; GO:0005856,actin filament capping; calcium ion binding; cell cortex; cytoskeleton,PF13499;PF08726;PF00018;PF00435;,,,,,,,,,SPTN1_CHICK,Gallus gallus (Chicken),actin filament capping [GO:0051693] comp140032_c0_seq9,2186,47.1638,0.61668089,0,0,,0,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,0,CHOYP_KALRN.1.2,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp140034_c1_seq1,1412,34.7025,0.38543391,7,7,,6.00E-60,Q5F3A2,Charged multivesicular body protein 2b (Chromatin-modifying protein 2b) (CHMP2b),Charged multivesicular body protein 2b (Chromatin-modifying protein 2b) (CHMP2b),GO:0005829; GO:0031902; GO:0015031,cytosol; late endosome membrane; protein transport,PF03357;,,,,,,,,,CHM2B_CHICK,Gallus gallus (Chicken),protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp140034_c1_seq3,1482,34.0081,0.33337095,9,0,,9.00E-60,Q5F3A2,Charged multivesicular body protein 2b (Chromatin-modifying protein 2b) (CHMP2b),Charged multivesicular body protein 2b (Chromatin-modifying protein 2b) (CHMP2b),GO:0005829; GO:0031902; GO:0015031,cytosol; late endosome membrane; protein transport,PF03357;,1.00E-93,CHOYP_LOC100375204.2.2,,,,,,,CHM2B_CHICK,Gallus gallus (Chicken),protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp140036_c0_seq1,1117,37.8693,0.38576586,39,34,,4.00E-30,Q9EPL8,Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7),Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7),GO:0005794; GO:0042393; GO:0005634; GO:0006606,Golgi apparatus; histone binding; nucleus; protein import into nucleus,PF08506;PF03810;,,,,,,,,,IPO7_MOUSE,Mus musculus (Mouse),innate immune response [GO:0045087]; protein import into nucleus [GO:0006606]; signal transduction [GO:0007165] comp140036_c0_seq2,1199,37.6981,0.38514801,27,52,,2.00E-07,Q7TMY7,Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8),Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8),GO:0042626; GO:0005737; GO:0005887; GO:0006886; GO:0005634,"ATPase activity, coupled to transmembrane movement of substances; cytoplasm; integral to plasma membrane; intracellular protein transport; nucleus",PF08506;PF03810;,,,,,,,,,IPO8_MOUSE,Mus musculus (Mouse),protein import into nucleus [GO:0006606]; signal transduction [GO:0007165]; transport [GO:0006810] comp140039_c0_seq14,904,43.4735,0.59373925,457,13795,,7.00E-56,P30568,Glutathione S-transferase A (GST-A) (EC 2.5.1.18) (GST class-theta),Glutathione S-transferase A (GST-A) (EC 2.5.1.18) (GST class-theta),GO:0005737; GO:0004364,cytoplasm; glutathione transferase activity,PF14497;PF13417;,4.00E-15,CHOYP_FAF2.1.1,4.00E-38,ruditapes_lrc32134,,,,,GSTA_PLEPL,Pleuronectes platessa (European plaice), comp140042_c0_seq1,1024,35.7422,0.3701144,191,696,,,,,,,,,,,6.00E-11,ruditapes_lrc19277,,,,,,, comp140043_c0_seq1,1450,37.5172,0.45285319,5619,7971,,1.00E-55,P24329,Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),GO:0008097; GO:0016226; GO:0005743; GO:0005759; GO:0005886; GO:0035928; GO:0004792,5S rRNA binding; iron-sulfur cluster assembly; mitochondrial inner membrane; mitochondrial matrix; plasma membrane; rRNA import into mitochondrion; thiosulfate sulfurtransferase activity,PF00581;,,,2.00E-31,ruditapes_c9218,,,,,THTR_RAT,Rattus norvegicus (Rat),"epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" comp140044_c0_seq3,2085,37.6019,0.39577188,4,0,,1.00E-17,Q1RMR0,DNA-directed RNA polymerase III subunit RPC7-like (RNA polymerase III subunit C7-like) (DNA-directed RNA polymerase III subunit G-like),DNA-directed RNA polymerase III subunit RPC7-like (RNA polymerase III subunit C7-like) (DNA-directed RNA polymerase III subunit G-like),,,PF11705;,3.00E-26,CHOYP_POLR3GL.1.1,,,,,,,RPC7L_BOVIN,Bos taurus (Bovine),regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription initiation from RNA polymerase III promoter [GO:0006384] comp140047_c0_seq2,602,36.0465,0.21036165,32,106,,2.00E-07,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140049_c1_seq1,1741,36.5882,0.50618241,198,192,,3.00E-30,Q803M0,Protein phosphatase 1 regulatory subunit 3B,Protein phosphatase 1 regulatory subunit 3B,GO:0005977,glycogen metabolic process,PF03370;,8.00E-14,CHOYP_LOC100373497.1.1,,,,,,,PPR3B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glycogen metabolic process [GO:0005977]; regulation of glycogen catabolic process [GO:0005981] comp140052_c0_seq1,2283,39.597,0.52601209,12,3,,1.00E-28,Q5R8L2,Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4),Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4),GO:0031519; GO:0016568; GO:0005737; GO:0030890; GO:0033092; GO:0051443; GO:0006355; GO:0006351; GO:0000151; GO:0008270,"PcG protein complex; chromatin modification; cytoplasm; positive regulation of B cell proliferation; positive regulation of immature T cell proliferation in thymus; positive regulation of ubiquitin-protein ligase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin ligase complex; zinc ion binding",PF16207;,,,,,,,,,BMI1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"brain development [GO:0007420]; DNA methylation [GO:0006306]; embryonic skeletal system morphogenesis [GO:0048704]; histone acetylation [GO:0016573]; histone ubiquitination [GO:0016574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; rostrocaudal neural tube patterning [GO:0021903]; somatic stem cell division [GO:0048103]; transcription, DNA-templated [GO:0006351]" comp140052_c0_seq2,1692,38.4161,0.54538411,0,0,,5.00E-06,Q9LS86,Probable E3 ubiquitin protein ligase DRIPH (EC 6.3.2.-) (DREB2A-interacting protein homolog),Probable E3 ubiquitin protein ligase DRIPH (EC 6.3.2.-) (DREB2A-interacting protein homolog),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,,,,,,,,,,DRIPH_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ubiquitination [GO:0016567] comp140052_c0_seq3,2290,39.6943,0.52203497,2,49,,8.00E-36,Q9BYE7,Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134),Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134),GO:0003677; GO:0035102; GO:0045892; GO:0003700; GO:0006351; GO:0008270,"DNA binding; PRC1 complex; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,PCGF6_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp140054_c0_seq2,2443,42.7753,0.60019656,19,20,,7.00E-41,A9JTP3,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIRC7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966] comp140054_c0_seq4,2461,42.7875,0.58663076,29,9,,5.00E-39,O62640,Putative inhibitor of apoptosis,Putative inhibitor of apoptosis,GO:0006915; GO:0005737; GO:0070266; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0016567; GO:0042981; GO:0004842; GO:0008270,apoptotic process; cytoplasm; necroptosis; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; protein ubiquitination; regulation of apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,1.00E-14,CHOYP_LOC100647366.1.2,,,,,,,PIAP_PIG,Sus scrofa (Pig),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121] comp140057_c0_seq4,1185,37.8059,0.35637045,10,7,,8.00E-11,Q8IY33,MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2),MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2),GO:0031532; GO:0051015; GO:0032432; GO:0030041; GO:0005829; GO:0032456; GO:0006897; GO:0031005; GO:0043005; GO:0031175; GO:0005886; GO:0055037; GO:0034446; GO:0005923; GO:0070830; GO:0008270,actin cytoskeleton reorganization; actin filament binding; actin filament bundle; actin filament polymerization; cytosol; endocytic recycling; endocytosis; filamin binding; neuron projection; neuron projection development; plasma membrane; recycling endosome; substrate adhesion-dependent cell spreading; tight junction; tight junction assembly; zinc ion binding,PF00307;PF12130;PF00412;,,,,,,,,,MILK2_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; bicellular tight junction assembly [GO:0070830]; endocytic recycling [GO:0032456]; neuron projection development [GO:0031175]; positive regulation of protein targeting to mitochondrion [GO:1903955]; substrate adhesion-dependent cell spreading [GO:0034446] comp140057_c2_seq1,2852,44.0743,0.38886208,0,17,,3.00E-37,Q4IJ84,DNA repair protein RAD5 (EC 3.6.4.-),DNA repair protein RAD5 (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0006281; GO:0005737; GO:0004386; GO:0005634; GO:0008270,ATP binding; DNA binding; DNA repair; cytoplasm; helicase activity; nucleus; zinc ion binding,PF00271;PF08797;PF00176;PF00097;,,,,,,,,,RAD5_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),double-strand break repair [GO:0006302]; error-prone translesion synthesis [GO:0042276]; free ubiquitin chain polymerization [GO:0010994]; protein polyubiquitination [GO:0000209] comp140057_c2_seq2,2973,44.1305,0.40113873,0,0,,1.00E-46,O60177,Uncharacterized ATP-dependent helicase C23E6.02 (EC 3.6.4.-),Uncharacterized ATP-dependent helicase C23E6.02 (EC 3.6.4.-),GO:0005524; GO:0004003; GO:0003677; GO:0006338; GO:0000724; GO:0045005; GO:0000790; GO:0004842; GO:0008270,ATP binding; ATP-dependent DNA helicase activity; DNA binding; chromatin remodeling; double-strand break repair via homologous recombination; maintenance of fidelity involved in DNA-dependent DNA replication; nuclear chromatin; ubiquitin-protein ligase activity; zinc ion binding,PF00271;PF00176;PF00097;,1.00E-45,CHOYP_TTF2.1.1,,,,,,,YG42_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic DNA replication maintenance of fidelity [GO:1990505]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]" comp140057_c2_seq3,1803,42.7066,0.39757588,0,0,,7.00E-149,Q9UNY4,Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2),Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2),GO:0005524; GO:0008026; GO:0003677; GO:0008094; GO:0008380; GO:0005737; GO:0006397; GO:0006355; GO:0005681; GO:0006369; GO:0008023; GO:0008270,"ATP binding; ATP-dependent helicase activity; DNA binding; DNA-dependent ATPase activity; RNA splicing; cytoplasm; mRNA processing; regulation of transcription, DNA-dependent; spliceosomal complex; termination of RNA polymerase II transcription; transcription elongation factor complex; zinc ion binding",PF00271;PF00176;PF06839;,,,,,,,,,TTF2_HUMAN,Homo sapiens (Human),"DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]" comp140057_c2_seq4,876,41.21,0.43946189,0,0,,6.00E-34,P0CQ67,DNA repair protein RAD5 (EC 3.6.4.-),DNA repair protein RAD5 (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0006281; GO:0005737; GO:0004386; GO:0005634; GO:0008270,ATP binding; DNA binding; DNA repair; cytoplasm; helicase activity; nucleus; zinc ion binding,PF00271;PF08797;PF00176;PF00097;,,,,,,,,,RAD5_CRYNB,Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans),DNA repair [GO:0006281] comp140057_c2_seq6,1924,42.8274,0.40673608,0,0,,2.00E-148,Q9UNY4,Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2),Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2),GO:0005524; GO:0008026; GO:0003677; GO:0008094; GO:0008380; GO:0005737; GO:0006397; GO:0006355; GO:0005681; GO:0006369; GO:0008023; GO:0008270,"ATP binding; ATP-dependent helicase activity; DNA binding; DNA-dependent ATPase activity; RNA splicing; cytoplasm; mRNA processing; regulation of transcription, DNA-dependent; spliceosomal complex; termination of RNA polymerase II transcription; transcription elongation factor complex; zinc ion binding",PF00271;PF00176;PF06839;,1.00E-31,CHOYP_TTF2.1.1,,,,,,,TTF2_HUMAN,Homo sapiens (Human),"DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]" comp140057_c2_seq7,997,41.6249,0.45292168,0,0,,1.00E-33,P0CQ67,DNA repair protein RAD5 (EC 3.6.4.-),DNA repair protein RAD5 (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0006281; GO:0005737; GO:0004386; GO:0005634; GO:0008270,ATP binding; DNA binding; DNA repair; cytoplasm; helicase activity; nucleus; zinc ion binding,PF00271;PF08797;PF00176;PF00097;,,,,,,,,,RAD5_CRYNB,Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans),DNA repair [GO:0006281] comp140057_c2_seq8,1949,43.0477,0.41929646,0,0,,3.00E-30,Q4IJ84,DNA repair protein RAD5 (EC 3.6.4.-),DNA repair protein RAD5 (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0006281; GO:0005737; GO:0004386; GO:0005634; GO:0008270,ATP binding; DNA binding; DNA repair; cytoplasm; helicase activity; nucleus; zinc ion binding,PF00271;PF08797;PF00176;PF00097;,,,,,,,,,RAD5_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),double-strand break repair [GO:0006302]; error-prone translesion synthesis [GO:0042276]; free ubiquitin chain polymerization [GO:0010994]; protein polyubiquitination [GO:0000209] comp140059_c0_seq1,3849,42.6604,0.41833378,249,0,male,3.00E-19,A6NNT2,Putative uncharacterized protein C16orf96,Uncharacterized protein C16orf96,,,PF16043;,3.00E-93,CHOYP_BRAFLDRAFT_119031.2.2,,,,,,,CP096_HUMAN,Homo sapiens (Human), comp140059_c0_seq2,3816,42.6101,0.41706734,389,0,male,7.00E-63,Q9H0J4,Glutamine-rich protein 2,Glutamine-rich protein 2,,,PF16043;,3.00E-112,CHOYP_BRAFLDRAFT_119031.2.2,,,,,,,QRIC2_HUMAN,Homo sapiens (Human), comp140060_c0_seq4,1196,41.4716,0.42901159,37,436,,5.00E-83,Q8VCX6,Kaptin,Kaptin,GO:0030426; GO:0048471; GO:0032420,growth cone; perinuclear region of cytoplasm; stereocilium,,,,,,,,,,KPTN_MOUSE,Mus musculus (Mouse),actin filament organization [GO:0007015] comp140064_c0_seq3,1677,38.9982,0.6058736,0,137,,8.00E-45,Q9CY66,H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1),H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1),GO:0015030; GO:0031429; GO:0001651; GO:0001522; GO:0006364; GO:0030515,Cajal body; box H/ACA snoRNP complex; dense fibrillar component; pseudouridine synthesis; rRNA processing; snoRNA binding,PF04410;,3.00E-69,CHOYP_GAR1.2.2,,,,,,,GAR1_MOUSE,Mus musculus (Mouse),pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364] comp140065_c2_seq4,1192,36.6611,0.50337588,59,341,,2.00E-38,Q08DU1,rRNA-processing protein UTP23 homolog,rRNA-processing protein UTP23 homolog,GO:0005730; GO:0006364; GO:0032040,nucleolus; rRNA processing; small-subunit processome,PF04900;,,,9.00E-79,ruditapes2_c2393,,,,,UTP23_BOVIN,Bos taurus (Bovine),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp140067_c0_seq1,1730,42.1965,0.3379109,151,374,,2.00E-122,Q9GM44,HEAT repeat-containing protein 1 (Protein BAP28) (Fragment),HEAT repeat-containing protein 1 (Protein BAP28) (Fragment),GO:0005730; GO:0006364; GO:0030529,nucleolus; rRNA processing; ribonucleoprotein complex,PF08146;,2.00E-47,CHOYP_HEAT1.1.1,,,,,,,HEAT1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),rRNA processing [GO:0006364] comp140067_c2_seq1,621,45.4106,0.37551036,23,34,,2.00E-22,Q4P937,U3 small nucleolar RNA-associated protein 10,U3 small nucleolar RNA-associated protein 10,GO:0016021; GO:0005730; GO:0006364; GO:0030529,integral to membrane; nucleolus; rRNA processing; ribonucleoprotein complex,PF08146;PF12397;,5.00E-18,CHOYP_HEAT1.1.1,,,,,,,UTP10_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]" comp140070_c0_seq1,447,41.1633,0.48461781,5,11,,7.00E-07,Q54PB2,Multiple RNA-binding domain-containing protein 1 (RNA-binding motif protein 19 homolog) (RNA-binding protein 19 homolog),Multiple RNA-binding domain-containing protein 1 (RNA-binding motif protein 19 homolog) (RNA-binding protein 19 homolog),GO:0005730; GO:0000166; GO:0006364; GO:0030515,nucleolus; nucleotide binding; rRNA processing; snoRNA binding,PF00076;,,,,,,,,,MRD1_DICDI,Dictyostelium discoideum (Slime mold),rRNA processing [GO:0006364] comp140070_c0_seq2,1254,36.6826,0.43028599,127,564,,2.00E-87,Q9UNP9,Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E),Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E),GO:0003723; GO:0071013; GO:0016018; GO:0000398; GO:0000166; GO:0003755; GO:0045070; GO:0006457; GO:0006355,"RNA binding; catalytic step 2 spliceosome; cyclosporin A binding; mRNA splicing, via spliceosome; nucleotide binding; peptidyl-prolyl cis-trans isomerase activity; positive regulation of viral genome replication; protein folding; regulation of transcription, DNA-dependent",PF00160;PF00076;,7.00E-108,CHOYP_PPIE.1.1,4.00E-52,ruditapes2_c3221,,,,,PPIE_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp140070_c0_seq3,447,41.1633,0.48328181,0,0,,5.00E-13,Q8T6B9,Poly(U)-binding-splicing factor half pint (Protein half pint) (68 kDa poly(U)-binding-splicing factor) (PUF60 homolog),Poly(U)-binding-splicing factor half pint (Protein half pint) (68 kDa poly(U)-binding-splicing factor) (PUF60 homolog),GO:0000380; GO:0071013; GO:0007282; GO:0003729; GO:0006376; GO:0022008; GO:0000166; GO:0048477; GO:0008266; GO:0071011; GO:0043234; GO:0000381; GO:0001558,"alternative mRNA splicing, via spliceosome; catalytic step 2 spliceosome; cystoblast division; mRNA binding; mRNA splice site selection; neurogenesis; nucleotide binding; oogenesis; poly(U) RNA binding; precatalytic spliceosome; protein complex; regulation of alternative mRNA splicing, via spliceosome; regulation of cell growth",PF00076;,,,,,,,,,PUF68_DROME,Drosophila melanogaster (Fruit fly),"alternative mRNA splicing, via spliceosome [GO:0000380]; cystoblast division [GO:0007282]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]" comp140072_c0_seq1,3207,45.5254,0.48886711,6,2,,2.00E-06,Q6NS45,Coiled-coil domain-containing protein 66,Coiled-coil domain-containing protein 66,GO:0060060; GO:0046548,post-embryonic retina morphogenesis in camera-type eye; retinal rod cell development,,,,,,,,,,CCD66_MOUSE,Mus musculus (Mouse),detection of light stimulus involved in visual perception [GO:0050908]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retinal rod cell development [GO:0046548] comp140072_c0_seq15,1616,45.0495,0.37037617,0,0,,,,,,,,,2.00E-21,CHOYP_BRAFLDRAFT_121183.1.8,,,,,,,,, comp140072_c0_seq2,2353,44.7514,0.49378671,9,0,,,,,,,,,7.00E-23,CHOYP_BRAFLDRAFT_121183.8.8,,,,,,,,, comp140072_c0_seq6,947,42.5554,0.25901668,0,0,,,,,,,,,3.00E-23,CHOYP_BRAFLDRAFT_121183.8.8,,,,,,,,, comp140072_c0_seq9,3305,45.1437,0.519253,0,4,,2.00E-06,Q6NS45,Coiled-coil domain-containing protein 66,Coiled-coil domain-containing protein 66,GO:0060060; GO:0046548,post-embryonic retina morphogenesis in camera-type eye; retinal rod cell development,,,,,,,,,,CCD66_MOUSE,Mus musculus (Mouse),detection of light stimulus involved in visual perception [GO:0050908]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retinal rod cell development [GO:0046548] comp140076_c0_seq5,544,38.9706,0.68943939,16,166,,1.00E-34,Q8JIS3,D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),GO:0042732; GO:0050038; GO:0005737; GO:0047880,D-xylose metabolic process; L-xylulose reductase (NADP+) activity; cytoplasm; erythrulose reductase activity,,,,,,,,,,DER_CHICK,Gallus gallus (Chicken),D-xylose metabolic process [GO:0042732] comp140077_c0_seq1,2251,40.1599,0.57764511,5587,18143,,0,P25708,"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit)","NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit)",GO:0051539; GO:0010181; GO:0051287; GO:0008137; GO:0046872; GO:0005747,"4 iron, 4 sulfur cluster binding; FMN binding; NAD binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; mitochondrial respiratory chain complex I",PF01512;PF10589;PF10531;,0,CHOYP_BRAFLDRAFT_273832.1.1,2.00E-47,ruditapes_c10155,,,,,NDUV1_BOVIN,Bos taurus (Bovine),aerobic respiration [GO:0009060] comp140078_c0_seq2,1682,40.4281,0.6262951,16,112,,3.00E-54,Q66H59,N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase),N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase),GO:0019262; GO:0008747; GO:0005975; GO:0005737,N-acetylneuraminate catabolic process; N-acetylneuraminate lyase activity; carbohydrate metabolic process; cytoplasm,PF00701;,,,,,,,,,NPL_RAT,Rattus norvegicus (Rat),carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262] comp140079_c0_seq1,1384,40.7514,0.83994676,33,302,,6.00E-51,P55918,Microfibril-associated glycoprotein 4 (36 kDa microfibril-associated glycoprotein) (36 kDa MAP),Microfibril-associated glycoprotein 4 (36 kDa microfibril-associated glycoprotein) (36 kDa MAP),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF00147;,,,,,,,,,MFAP4_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; cellular response to UV-B [GO:0071493]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; regulation of collagen metabolic process [GO:0010712]; UV protection [GO:0009650] comp140079_c0_seq2,1100,41.8182,0.94287627,5,19,,2.00E-50,Q00546,Tenascin-R (TN-R) (Restrictin),Tenascin-R (TN-R) (Restrictin),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF00147;PF00041;,,,,,,,,,TENR_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; regulation of neurogenesis [GO:0050767] comp140084_c0_seq1,1782,31.9304,0.39819859,275,1854,,,,,,,,,,,3.00E-17,ruditapes_c7047,,,,,,, comp140085_c0_seq1,2822,42.8774,0.20056782,3,0,,,,,,,,,5.00E-19,CHOYP_LOC100369350.5.6,,,,,,,,, comp140085_c0_seq3,269,47.2119,0.64949351,0,0,,,,,,,,,4.00E-20,CHOYP_LOC100369350.5.6,,,,,,,,, comp140086_c1_seq2,316,35.1266,0.10434601,27,50,,,,,,,,,,,4.00E-19,ruditapes2_c3017,,,,,,, comp140086_c1_seq6,542,31.7343,0.22100197,0,0,,,,,,,,,,,1.00E-15,ruditapes_c3510,,,,,,, comp140089_c0_seq1,2304,44.6615,0.61872225,1,14,,1.00E-29,P0CB05,Centrosomal protein of 63 kDa (Cep63),Centrosomal protein of 63 kDa (Cep63),GO:0000077; GO:0051301; GO:0005813; GO:0005737; GO:0007067; GO:0042770; GO:0051225; GO:0000922,DNA damage checkpoint; cell division; centrosome; cytoplasm; mitosis; signal transduction in response to DNA damage; spindle assembly; spindle pole,PF17045;,,,,,,,,,CEP63_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; DNA damage checkpoint [GO:0000077]; mitotic nuclear division [GO:0007067]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225] comp140089_c0_seq3,2169,44.6289,0.62368467,0,0,,,,,,,,,5.00E-30,CHOYP_CEP63.1.2,,,,,,,,, comp140089_c0_seq4,2558,44.0188,0.63315199,0,0,,1.00E-17,Q5U3Z6,Coiled-coil domain-containing protein 67,Deuterosome protein 1 (Coiled-coil domain-containing protein 67),,,PF17045;,,,,,,,,,CCD67_RAT,Rattus norvegicus (Rat),cell projection organization [GO:0030030]; centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; multi-ciliated epithelial cell differentiation [GO:1903251] comp140089_c0_seq5,2210,44.6606,0.59610763,0,0,,,,,,,,,6.00E-30,CHOYP_CEP63.2.2,,,,,,,,, comp140089_c0_seq6,2074,44.6962,0.5975466,6,0,,1.00E-38,P0CB05,Centrosomal protein of 63 kDa (Cep63),Centrosomal protein of 63 kDa (Cep63),GO:0000077; GO:0051301; GO:0005813; GO:0005737; GO:0007067; GO:0042770; GO:0051225; GO:0000922,DNA damage checkpoint; cell division; centrosome; cytoplasm; mitosis; signal transduction in response to DNA damage; spindle assembly; spindle pole,PF17045;,1.00E-30,CHOYP_CEP63.1.2,,,,,,,CEP63_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; DNA damage checkpoint [GO:0000077]; mitotic nuclear division [GO:0007067]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225] comp140093_c0_seq3,1422,39.0999,0.19134583,227,22,,7.00E-157,Q27567,"Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)","Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)",GO:0051287; GO:0005975; GO:0046168; GO:0004367; GO:0009331; GO:0006650,NAD binding; carbohydrate metabolic process; glycerol-3-phosphate catabolic process; glycerol-3-phosphate dehydrogenase [NAD+] activity; glycerol-3-phosphate dehydrogenase complex; glycerophospholipid metabolic process,PF07479;PF01210;,4.00E-169,CHOYP_GPDA.2.2,,,2.00E-74,AM858776.p.cg.6,8,male gonad,GPDA_DROEZ,Drosophila ezoana (Fruit fly),carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophospholipid metabolic process [GO:0006650] comp140093_c0_seq4,402,36.5672,0.54990594,8,0,,4.00E-06,Q12264,Putative uncharacterized protein YDL023C,Putative uncharacterized protein YDL023C,,,,2.00E-15,CHOYP_GPDA.1.2,,,,,,,YD023_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp140094_c0_seq1,2607,40.1227,0.51562456,2428,32,,2.00E-177,P20794,Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell-associated kinase),Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell-associated kinase),GO:0005524; GO:0030154; GO:0005813; GO:0004693; GO:0005737; GO:0030496; GO:0072686; GO:0007275; GO:0005634; GO:0045494; GO:0001917; GO:0001750; GO:0046777; GO:0004672; GO:0006355; GO:0007283; GO:0003713; GO:0006351,"ATP binding; cell differentiation; centrosome; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; midbody; mitotic spindle; multicellular organismal development; nucleus; photoreceptor cell maintenance; photoreceptor inner segment; photoreceptor outer segment; protein autophosphorylation; protein kinase activity; regulation of transcription, DNA-dependent; spermatogenesis; transcription coactivator activity; transcription, DNA-dependent",PF00069;,0,CHOYP_LOC100367705.1.1,,,,,,,MAK_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; photoreceptor cell maintenance [GO:0045494]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp140097_c0_seq8,600,40.5,0.16347115,0,0,,1.00E-09,Q9SB51,Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (AtUBP16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (AtUBP16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),GO:0008283; GO:0008234; GO:0009908; GO:0016021; GO:0048366; GO:0046872; GO:0016579; GO:1901000; GO:0009651; GO:0048364; GO:0004221; GO:0006511,cell proliferation; cysteine-type peptidase activity; flower development; integral to membrane; leaf development; metal ion binding; protein deubiquitination; regulation of response to salt stress; response to salt stress; root development; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;PF01753;,,,,,,,,,UBP16_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell proliferation [GO:0008283]; flower development [GO:0009908]; leaf development [GO:0048366]; protein deubiquitination [GO:0016579]; regulation of response to salt stress [GO:1901000]; response to salt stress [GO:0009651]; root development [GO:0048364]; shoot system development [GO:0048367]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140100_c0_seq1,449,48.3296,0.39246662,59,11,,6.00E-07,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp140101_c0_seq2,1285,42.2568,0.52668974,27,31,,1.00E-58,P35821,Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2),Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2),GO:0031532; GO:0005829; GO:0005769; GO:0005789; GO:0030968; GO:0008286; GO:0005886; GO:0035791; GO:0004725; GO:0030100; GO:1902202; GO:0009966; GO:0008270,actin cytoskeleton reorganization; cytosol; early endosome; endoplasmic reticulum membrane; endoplasmic reticulum unfolded protein response; insulin receptor signaling pathway; plasma membrane; platelet-derived growth factor receptor-beta signaling pathway; protein tyrosine phosphatase activity; regulation of endocytosis; regulation of hepatocyte growth factor receptor signaling pathway; regulation of signal transduction; zinc ion binding,PF00102;,,,,,,,,,PTN1_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; endoplasmic reticulum unfolded protein response [GO:0030968]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; response to endoplasmic reticulum stress [GO:0034976] comp140101_c1_seq1,1712,39.5444,0.32544896,91,436,,1.00E-76,Q9H501,ESF1 homolog (ABT1-associated protein),ESF1 homolog (ABT1-associated protein),GO:0005730; GO:0005654; GO:0006355; GO:0006351,"nucleolus; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08159;,,,,,,,,,ESF1_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140101_c1_seq4,316,32.9114,0.71639136,7,15,,,,,,,,,2.00E-20,CHOYP_ESF1.1.1,,,,,,,,, comp140102_c0_seq1,2522,28.866,0.34882333,387,2859,,,,,,,,,,,6.00E-22,ruditapes_c16120,,,,,,, comp140103_c0_seq1,1735,41.9597,0.72405428,122,667,,6.00E-08,A2ARV4,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008283; GO:0005905; GO:0030139; GO:0005783; GO:0005768; GO:0030900; GO:0016021; GO:0004872; GO:0006898; GO:0006766,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cell proliferation; coated pit; endocytic vesicle; endoplasmic reticulum; endosome; forebrain development; integral to membrane; receptor activity; receptor-mediated endocytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,,,1.00E-66,ruditapes_c8698,,,,,LRP2_MOUSE,Mus musculus (Mouse),aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; forebrain development [GO:0030900]; heart development [GO:0007507]; receptor-mediated endocytosis [GO:0006898]; ventricular septum development [GO:0003281]; vitamin metabolic process [GO:0006766] comp140104_c0_seq1,1820,40.3846,0.54358225,1275,203,,1.00E-122,Q4R642,T-complex-associated testis-expressed protein 1 (Tcte-1),T-complex-associated testis-expressed protein 1 (Tcte-1),,,PF13516;,0,CHOYP_LOC100378816.1.1,,,4.00E-108,AM858229.p.cg.6,5,,TCTE1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp140108_c0_seq1,944,40.678,0.37433197,94,435,,1.00E-82,Q9JI19,Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein),Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein),GO:0012505; GO:0016020; GO:0005634,endomembrane system; membrane; nucleus,PF05427;,1.00E-53,CHOYP_FIBP.1.1,,,,,,,FIBP_MOUSE,Mus musculus (Mouse),platelet aggregation [GO:0070527] comp140109_c3_seq2,681,40.5286,1.14604039,0,0,,6.00E-07,Q8JFG3,Tumor necrosis factor (TNF-alpha),Tumor necrosis factor (TNF-alpha),GO:0005615; GO:0006955; GO:0016021,extracellular space; immune response; integral to membrane,PF00229;,,,,,,,,,TNFA_SPAAU,Sparus aurata (Gilthead sea bream),immune response [GO:0006955] comp140109_c3_seq5,700,38.4286,1.08538156,0,0,,8.00E-07,Q8JFG3,Tumor necrosis factor (TNF-alpha),Tumor necrosis factor (TNF-alpha),GO:0005615; GO:0006955; GO:0016021,extracellular space; immune response; integral to membrane,PF00229;,,,,,,,,,TNFA_SPAAU,Sparus aurata (Gilthead sea bream),immune response [GO:0006955] comp140113_c2_seq2,2578,43.4833,0.49835756,121,761,,3.00E-50,Q62315,Protein Jumonji (Jumonji/ARID domain-containing protein 2),Protein Jumonji (Jumonji/ARID domain-containing protein 2),GO:0003677; GO:0035098; GO:0003682; GO:0016568; GO:0035097; GO:0001889; GO:0008285; GO:0031061; GO:0000122; GO:0051574; GO:0048536; GO:0048863; GO:0048538; GO:0006351,"DNA binding; ESC/E(Z) complex; chromatin binding; chromatin modification; histone methyltransferase complex; liver development; negative regulation of cell proliferation; negative regulation of histone methylation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone H3-K9 methylation; spleen development; stem cell differentiation; thymus development; transcription, DNA-dependent",PF01388;PF02373;PF02375;PF02928;,,,,,,,,,JARD2_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; liver development [GO:0001889]; negative regulation of cell proliferation [GO:0008285]; negative regulation of histone methylation [GO:0031061]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K9 methylation [GO:0051574]; regulation of cell proliferation [GO:0042127]; spleen development [GO:0048536]; stem cell differentiation [GO:0048863]; thymus development [GO:0048538]; transcription, DNA-templated [GO:0006351]" comp140115_c0_seq1,2290,38.6463,0.53382346,0,0,,1.00E-116,Q21086,Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1),Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1),GO:0005525; GO:0003924; GO:0007281; GO:0002119; GO:0005730; GO:0005654; GO:0042127; GO:0040014; GO:0042254,GTP binding; GTPase activity; germ cell development; nematode larval development; nucleolus; nucleoplasm; regulation of cell proliferation; regulation of multicellular organism growth; ribosome biogenesis,PF08701;PF01926;,,,,,,,,,GNL3_CAEEL,Caenorhabditis elegans,germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014]; ribosome biogenesis [GO:0042254] comp140115_c0_seq2,2082,39.001,0.49909529,4,0,,3.00E-58,Q6P4W5,Guanine nucleotide-binding protein-like 3 (Nucleostemin-like protein),Guanine nucleotide-binding protein-like 3 (Nucleostemin-like protein),GO:0005525; GO:0005730; GO:0042127,GTP binding; nucleolus; regulation of cell proliferation,PF08701;PF01926;,2.00E-93,CHOYP_LOC100313691.1.1,,,,,,,GNL3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),regulation of cell proliferation [GO:0042127]; ribosome biogenesis [GO:0042254] comp140115_c0_seq3,2066,38.9642,0.49074086,0,0,,6.00E-99,Q8MT06,Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin 1) (Nucleostemin homolog),Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin 1) (Nucleostemin homolog),GO:0016887; GO:0006254; GO:0043273; GO:0005525; GO:0003924; GO:0046052; GO:0048588; GO:0001652; GO:0007494; GO:0090070; GO:0042127; GO:0046626; GO:0040014; GO:0042273; GO:0007431,ATPase activity; CTP catabolic process; CTPase activity; GTP binding; GTPase activity; UTP catabolic process; developmental cell growth; granular component; midgut development; positive regulation of ribosome biogenesis; regulation of cell proliferation; regulation of insulin receptor signaling pathway; regulation of multicellular organism growth; ribosomal large subunit biogenesis; salivary gland development,PF08701;PF01926;,2.00E-93,CHOYP_LOC100313691.1.1,,,,,,,GNL3_DROME,Drosophila melanogaster (Fruit fly),cellular response to starvation [GO:0009267]; mitotic spindle assembly [GO:0090307]; positive regulation of multicellular organism growth [GO:0040018]; regulation of cell proliferation [GO:0042127]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of multicellular organism growth [GO:0040014]; ribosomal large subunit biogenesis [GO:0042273] comp140115_c0_seq4,2274,38.6104,0.52641643,0,0,,1.00E-116,Q21086,Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1),Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1),GO:0005525; GO:0003924; GO:0007281; GO:0002119; GO:0005730; GO:0005654; GO:0042127; GO:0040014; GO:0042254,GTP binding; GTPase activity; germ cell development; nematode larval development; nucleolus; nucleoplasm; regulation of cell proliferation; regulation of multicellular organism growth; ribosome biogenesis,PF08701;PF01926;,,,,,,,,,GNL3_CAEEL,Caenorhabditis elegans,germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014]; ribosome biogenesis [GO:0042254] comp140116_c0_seq2,787,37.4841,0.76131886,1,105,,,,,,,,,7.00E-68,CHOYP_LSM5.1.3,,,,,,,,, comp140116_c0_seq3,861,37.863,0.68258011,723,1136,,1.00E-47,Q5R628,U6 snRNA-associated Sm-like protein LSm5,U6 snRNA-associated Sm-like protein LSm5,GO:0003723; GO:0008380; GO:0006397; GO:0005681,RNA binding; RNA splicing; mRNA processing; spliceosomal complex,PF01423;,3.00E-67,CHOYP_LSM5.2.3,6.00E-67,ruditapes_c11990,,,,,LSM5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp140117_c1_seq1,2390,41.9247,0.99316246,71,292,,8.00E-32,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp140118_c1_seq1,1269,40.2679,0.524727,168,531,,1.00E-65,Q9HC36,RNA methyltransferase-like protein 1 (EC 2.1.1.-),"rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1)",GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0005739,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; mitochondrion,PF00588;,,,,,,,,,RMTL1_HUMAN,Homo sapiens (Human),RNA methylation [GO:0001510]; rRNA processing [GO:0006364] comp140121_c0_seq1,1730,47.9769,0.51259423,19,27,,7.00E-76,Q9Y2L9,Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81),Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81),,,PF00307;PF13855;,8.00E-71,CHOYP_LRCH3.2.4,,,,,,,LRCH1_HUMAN,Homo sapiens (Human), comp140121_c0_seq4,762,42.3885,0.62162584,0,0,,2.00E-23,A4D1F6,Leucine-rich repeat and death domain-containing protein 1,Leucine-rich repeat and death domain-containing protein 1,GO:0007165,signal transduction,PF00560;PF13855;,,,,,,,,,LRRD1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp140121_c0_seq5,2051,48.2691,0.54478853,5,6,,8.00E-75,Q9Y2L9,Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81),Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81),,,PF00307;PF13855;,6.00E-67,CHOYP_LRCH3.3.4,,,,,,,LRCH1_HUMAN,Homo sapiens (Human), comp140122_c0_seq1,1312,38.7957,0.5312153,95,320,,3.00E-74,Q9BUE0,Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b),Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09637;,2.00E-21,CHOYP_MED18.1.1,,,,,,,MED18_HUMAN,Homo sapiens (Human),termination of RNA polymerase II transcription [GO:0006369] comp140123_c2_seq3,2587,35.4078,0.25091747,0,0,,4.00E-101,O14562,Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog),Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog),,,PF00240;,3.00E-122,CHOYP_HS90A.1.3,,,,,,,UBFD1_HUMAN,Homo sapiens (Human), comp140123_c2_seq9,2470,35.0607,0.26823713,0,0,,2.00E-101,O14562,Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog),Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog),,,PF00240;,3.00E-122,CHOYP_HS90A.1.3,,,,,,,UBFD1_HUMAN,Homo sapiens (Human), comp140125_c0_seq1,1792,39.8438,0.64626606,1,24,,9.00E-80,Q5ZLM2,Lariat debranching enzyme (EC 3.1.-.-),Lariat debranching enzyme (EC 3.1.-.-),GO:0008419; GO:0000375; GO:0000398; GO:0005634,"RNA lariat debranching enzyme activity; RNA splicing, via transesterification reactions; mRNA splicing, via spliceosome; nucleus",PF05011;PF00149;,,,,,,,,,DBR1_CHICK,Gallus gallus (Chicken),"mRNA splicing, via spliceosome [GO:0000398]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA splicing, via transesterification reactions [GO:0000375]" comp140125_c0_seq2,1843,39.6093,0.66150719,3,34,,1.00E-79,Q5ZLM2,Lariat debranching enzyme (EC 3.1.-.-),Lariat debranching enzyme (EC 3.1.-.-),GO:0008419; GO:0000375; GO:0000398; GO:0005634,"RNA lariat debranching enzyme activity; RNA splicing, via transesterification reactions; mRNA splicing, via spliceosome; nucleus",PF05011;PF00149;,2.00E-28,CHOYP_LOC577338.1.1,,,,,,,DBR1_CHICK,Gallus gallus (Chicken),"mRNA splicing, via spliceosome [GO:0000398]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA splicing, via transesterification reactions [GO:0000375]" comp140126_c0_seq1,3013,34.2184,0.52097663,25,76,,0,P12370,cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11),cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11),GO:0005524; GO:0007615; GO:0007448; GO:0048149; GO:0004691; GO:0005952; GO:0019933; GO:0048749; GO:0007480; GO:0007476; GO:0045475; GO:0045879; GO:0008355; GO:0007314; GO:0008103; GO:0005886; GO:0007228; GO:0008359; GO:0045187; GO:0007317; GO:0050804; GO:0040040,"ATP binding; anesthesia-resistant memory; anterior/posterior pattern specification, imaginal disc; behavioral response to ethanol; cAMP-dependent protein kinase activity; cAMP-dependent protein kinase complex; cAMP-mediated signaling; compound eye development; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing morphogenesis; locomotor rhythm; negative regulation of smoothened signaling pathway; olfactory learning; oocyte anterior/posterior axis specification; oocyte microtubule cytoskeleton polarization; plasma membrane; positive regulation of hh target transcription factor activity; regulation of bicoid mRNA localization; regulation of circadian sleep/wake cycle, sleep; regulation of pole plasm oskar mRNA localization; regulation of synaptic transmission; thermosensory behavior",PF00069;,0,CHOYP_CAPLA.2.2,,,,,,,KAPC_DROME,Drosophila melanogaster (Fruit fly),"anesthesia-resistant memory [GO:0007615]; anterior/posterior pattern specification, imaginal disc [GO:0007448]; behavioral response to ethanol [GO:0048149]; cAMP-mediated signaling [GO:0019933]; compound eye development [GO:0048749]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; memory [GO:0007613]; modulation of synaptic transmission [GO:0050804]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory learning [GO:0008355]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte microtubule cytoskeleton polarization [GO:0008103]; oogenesis [GO:0048477]; positive regulation of hh target transcription factor activity [GO:0007228]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of bicoid mRNA localization [GO:0008359]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of pole plasm oskar mRNA localization [GO:0007317]; rhythmic behavior [GO:0007622]; thermosensory behavior [GO:0040040]" comp140126_c0_seq2,3018,34.0292,0.52483664,58,57,,1.00E-102,P21901,Spermatozoon-associated protein kinase (SAK) (EC 2.7.11.1) (C-APL-B),Spermatozoon-associated protein kinase (SAK) (EC 2.7.11.1) (C-APL-B),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,0,CHOYP_CAPLA.1.2,,,1.00E-139,AM869290.p.cg.6,6,,KAPL_APLCA,Aplysia californica (California sea hare), comp140128_c0_seq4,1715,39.3003,0.48355071,29,59,,7.00E-13,A9JRX0,Male-specific lethal 1-like 1 (MSL1-like 1) (Male-specific lethal-1 homolog 1) (MSL-1),Male-specific lethal 1-like 1 (MSL1-like 1) (Male-specific lethal-1 homolog 1) (MSL-1),GO:0072487; GO:0043984,MSL complex; histone H4-K16 acetylation,PF16801;PF15275;,,,,,,,,,MSL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),histone H4-K16 acetylation [GO:0043984] comp140128_c0_seq8,1102,43.1942,0.5265107,71,70,,4.00E-15,A9JRX0,Male-specific lethal 1-like 1 (MSL1-like 1) (Male-specific lethal-1 homolog 1) (MSL-1),Male-specific lethal 1-like 1 (MSL1-like 1) (Male-specific lethal-1 homolog 1) (MSL-1),GO:0072487; GO:0043984,MSL complex; histone H4-K16 acetylation,PF16801;PF15275;,,,,,,,,,MSL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),histone H4-K16 acetylation [GO:0043984] comp140132_c0_seq1,897,46.4883,0.76452005,6,133,,3.00E-11,Q5T848,Probable G-protein coupled receptor 158,Probable G-protein coupled receptor 158,GO:0004930; GO:0016021; GO:0005886; GO:0072659; GO:0008277,G-protein coupled receptor activity; integral to membrane; plasma membrane; protein localization to plasma membrane; regulation of G-protein coupled receptor protein signaling pathway,PF00003;,,,,,,,,,GP158_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; protein localization to plasma membrane [GO:0072659]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp140132_c1_seq1,1627,42.2864,0.66358721,6,253,,,,,,,,,3.00E-32,CHOYP_SMP_149390.1.1,,,,,,,,, comp140132_c1_seq2,1221,40.3767,0.62365456,0,50,,4.00E-14,E1BBQ2,Probable G-protein coupled receptor 158,Probable G-protein coupled receptor 158,GO:0004930; GO:0016021; GO:0005886; GO:0072659; GO:0008277,G-protein coupled receptor activity; integral to membrane; plasma membrane; protein localization to plasma membrane; regulation of G-protein coupled receptor protein signaling pathway,PF00003;,,,,,,,,,GP158_BOVIN,Bos taurus (Bovine),G-protein coupled receptor signaling pathway [GO:0007186]; protein localization to plasma membrane [GO:0072659]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp140135_c1_seq2,1277,38.6061,0.43985572,3,340,female>male,,,,,,,,3.00E-36,CHOYP_LOC100371977.1.1,,,,,,,,, comp140135_c2_seq1,782,47.5703,0.5266414,10,137,,1.00E-25,Q5U312,Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14),Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14),GO:0005938; GO:0005856; GO:0005634,cell cortex; cytoskeleton; nucleus,PF12796;,,,,,,,,,RAI14_RAT,Rattus norvegicus (Rat), comp140136_c0_seq1,1716,43.8228,0.44082172,346,678,,5.00E-154,Q7T010,"Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112 homolog) (PET112-like)","Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112 homolog) (PET112-like)",GO:0005524; GO:0016884; GO:0005739; GO:0006412,"ATP binding; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; mitochondrion; translation",PF02934;PF02637;,1.00E-18,CHOYP_GATB.1.1,,,,,,,GATB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543] comp140141_c0_seq1,1533,38.03,0.5258892,565,4936,,8.00E-81,B5X0W9,Isochorismatase domain-containing protein 1,Isochorismatase domain-containing protein 1,GO:0003824,catalytic activity,PF00857;,2.00E-27,CHOYP_BRAFLDRAFT_264316.1.1,2.00E-50,ruditapes_c14986,,,,,ISOC1_SALSA,Salmo salar (Atlantic salmon),metabolic process [GO:0008152] comp140142_c0_seq1,1885,41.8037,1.00838751,0,0,,2.00E-13,Q86AF0,PA-phosphatase related-family protein DDB_G0271516,PA-phosphatase related-family protein DDB_G0271516,GO:0003824; GO:0016021; GO:0008152,catalytic activity; integral to membrane; metabolic process,PF01569;,,,,,,,,,Y7151_DICDI,Dictyostelium discoideum (Slime mold),phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; signal transduction [GO:0007165] comp140142_c0_seq4,1897,41.7501,1.0045853,0,0,,4.00E-47,Q99JY8,Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b),Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b),GO:0001568; GO:0060070; GO:0044329; GO:0044328; GO:0044330; GO:0016337; GO:0005789; GO:0001702; GO:0034109; GO:0016021; GO:0005178; GO:0042577; GO:0001933; GO:0008195; GO:0006644; GO:0050731; GO:0051091; GO:0050821; GO:0030111,blood vessel development; canonical Wnt receptor signaling pathway; canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion; canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration; canonical Wnt receptor signaling pathway involved in positive regulation of wound healing; cell-cell adhesion; endoplasmic reticulum membrane; gastrulation with mouth forming second; homotypic cell-cell adhesion; integral to membrane; integrin binding; lipid phosphatase activity; negative regulation of protein phosphorylation; phosphatidate phosphatase activity; phospholipid metabolic process; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of sequence-specific DNA binding transcription factor activity; protein stabilization; regulation of Wnt receptor signaling pathway,PF01569;,,,,,,,,,LPP3_MOUSE,Mus musculus (Mouse),Bergmann glial cell differentiation [GO:0060020]; blood vessel development [GO:0001568]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion [GO:0044329]; canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration [GO:0044328]; canonical Wnt signaling pathway involved in positive regulation of wound healing [GO:0044330]; cell adhesion [GO:0007155]; gastrulation with mouth forming second [GO:0001702]; homotypic cell-cell adhesion [GO:0034109]; negative regulation of protein phosphorylation [GO:0001933]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein stabilization [GO:0050821]; regulation of sphingolipid mediated signaling pathway [GO:1902068]; regulation of Wnt signaling pathway [GO:0030111]; single organismal cell-cell adhesion [GO:0016337] comp140143_c0_seq1,3231,44.0111,0.32599051,8,13,,1.00E-86,Q5T1M5,FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP and FKBP-like) (WAFL),FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP and FKBP-like) (WAFL),GO:0005884; GO:0030424; GO:0005769; GO:0006897; GO:0030426; GO:0010923; GO:0006457,actin filament; axon; early endosome; endocytosis; growth cone; negative regulation of phosphatase activity; protein folding,PF00254;,,,,,,,,,FKB15_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; negative regulation of phosphatase activity [GO:0010923]; protein folding [GO:0006457] comp140143_c0_seq2,2583,44.8316,0.33873962,0,0,,1.00E-20,Q54SR7,FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005528; GO:0016020; GO:0003755; GO:0006457,FK506 binding; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,4.00E-33,CHOYP_LOC100374077.1.1,,,,,,,FKBP2_DICDI,Dictyostelium discoideum (Slime mold),chaperone-mediated protein folding [GO:0061077] comp140143_c0_seq3,2613,44.8909,0.32514176,0,0,,6.00E-20,O74191,FK506-binding protein 39 kDa (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 39 kDa (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005528; GO:0000412; GO:0005730; GO:0003755; GO:0006457,FK506 binding; histone peptidyl-prolyl isomerization; nucleolus; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,,,,,,,,,FKBP4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chaperone-mediated protein folding [GO:0061077]; histone peptidyl-prolyl isomerization [GO:0000412]; nucleosome assembly [GO:0006334] comp140143_c0_seq4,3261,44.1276,0.33379121,17,16,,2.00E-11,P65764,FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (PPIase) (EC 5.2.1.8) (Rotamase),FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (PPIase) (EC 5.2.1.8) (Rotamase),GO:0003755; GO:0042597; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; periplasmic space; protein folding; protein peptidyl-prolyl isomerization,PF00254;PF01346;,5.00E-33,CHOYP_LOC100374077.1.1,,,,,,,FKBA_ECOL6,Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC),protein folding [GO:0006457] comp140144_c0_seq3,1613,46.4352,0.81771117,4,1971,female>male,5.00E-50,P13952,G2/mitotic-specific cyclin-B,G2/mitotic-specific cyclin-B,GO:0051301; GO:0007067; GO:0005634; GO:0000079,cell division; mitosis; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,,,,,,,,,CCNB_SPISO,Spisula solidissima (Atlantic surf-clam),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp140149_c0_seq3,1263,32.4624,0.30285624,3,12,,,,,,,,,,,1.00E-19,ruditapes_c11206,,,,,,, comp140150_c1_seq1,3847,45.36,0.55183633,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq11,4001,45.0887,0.56121579,0,0,,5.00E-11,D2H3M0,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_AILME,Ailuropoda melanoleuca (Giant panda),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp140150_c1_seq15,3889,45.6673,0.55846783,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq19,3561,46.1387,0.56084327,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq20,3767,45.8455,0.54742691,0,0,,8.00E-12,D2H3M0,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_AILME,Ailuropoda melanoleuca (Giant panda),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp140150_c1_seq21,3734,46.0096,0.54824574,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq22,3808,45.3256,0.55823035,0,0,,3.00E-12,D2H3M0,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_AILME,Ailuropoda melanoleuca (Giant panda),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp140150_c1_seq3,3593,45.9226,0.56627266,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq30,3712,45.6088,0.55012025,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq31,3599,46.2073,0.55337555,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq4,3921,45.5496,0.55681673,0,0,,5.00E-11,D2H3M0,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_AILME,Ailuropoda melanoleuca (Giant panda),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp140150_c1_seq6,3631,46.0755,0.55169097,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq7,3695,45.9811,0.55458644,0,0,,3.00E-12,D2H3M0,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_AILME,Ailuropoda melanoleuca (Giant panda),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp140150_c1_seq8,3728,45.8155,0.54861538,7,0,,2.00E-15,A6QLE1,Tudor domain-containing protein 7,Tudor domain-containing protein 7,GO:0043186; GO:0033391; GO:0007281; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,P granule; chromatoid body; germ cell development; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TDRD7_BOVIN,Bos taurus (Bovine),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140150_c1_seq9,3754,45.8444,0.56380623,0,0,,3.00E-21,A6NAF9,Tudor domain-containing protein 7A,Tudor domain-containing protein 7A,GO:0005737; GO:0070306; GO:0002089; GO:0003729; GO:0010608; GO:0035770; GO:0007283,cytoplasm; lens fiber cell differentiation; lens morphogenesis in camera-type eye; mRNA binding; posttranscriptional regulation of gene expression; ribonucleoprotein granule; spermatogenesis,PF12872;PF00567;,,,,,,,,,TRD7A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] comp140151_c0_seq2,2812,35.2063,0.74625748,3388,5,male>female,4.00E-29,Q5PQR6,Testicular haploid expressed gene protein-like,Testicular haploid expressed gene protein-like,,,PF14912;,,,,,,,,,THEGL_RAT,Rattus norvegicus (Rat), comp140152_c0_seq1,1609,42.2623,0.76632858,8,115,,8.00E-51,Q86UP9,Lipoma HMGIC fusion partner-like 3 protein,Lipoma HMGIC fusion partner-like 3 protein,GO:0016021,integral to membrane,PF10242;,,,,,,,,,LHPL3_HUMAN,Homo sapiens (Human), comp140152_c0_seq2,1648,42.1117,0.78084815,1,455,female>male,9.00E-51,Q86UP9,Lipoma HMGIC fusion partner-like 3 protein,Lipoma HMGIC fusion partner-like 3 protein,GO:0016021,integral to membrane,PF10242;,,,1.00E-66,ruditapes2_c2563,,,,,LHPL3_HUMAN,Homo sapiens (Human), comp140153_c0_seq1,2608,44.3252,0.57382706,39,143,,,,,,,,,7.00E-80,CHOYP_LS14A.2.3,,,,,,,,, comp140153_c0_seq2,2509,43.5632,0.57653683,156,128,,8.00E-35,Q5R4R4,Protein LSM14 homolog A (Protein FAM61A) (RNA-associated protein 55A),Protein LSM14 homolog A (Protein FAM61A) (RNA-associated protein 55A),GO:0039529; GO:0000932; GO:0033962; GO:0010494; GO:0003690; GO:0003725; GO:0007275; GO:0060340; GO:0006417; GO:0003727,RIG-I signaling pathway; cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; cytoplasmic stress granule; double-stranded DNA binding; double-stranded RNA binding; multicellular organismal development; positive regulation of type I interferon-mediated signaling pathway; regulation of translation; single-stranded RNA binding,PF09532;PF12701;,7.00E-80,CHOYP_LS14A.3.3,,,3.00E-80,AM855747.p.cg.6,4,,LS14A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cytoplasmic mRNA processing body assembly [GO:0033962]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417] comp140154_c1_seq2,451,47.6718,0.9959506,4,10,,,,,,,,,3.00E-38,CHOYP_LOC101242064.1.1,,,,,,,,, comp140154_c2_seq1,1911,43.5374,0.78684517,28,41,,0,Q04336,Uncharacterized protein YMR196W,Uncharacterized protein YMR196W,GO:0003824; GO:0008152,catalytic activity; metabolic process,,1.00E-106,CHOYP_LOC100636110.2.2,,,,,,,YM54_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487] comp140154_c2_seq2,1697,43.3117,0.83349229,11,28,,5.00E-10,O14255,Probable mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I),Probable mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I),GO:0005789; GO:0009272; GO:0016021; GO:0004573; GO:0009311; GO:0006487,endoplasmic reticulum membrane; fungal-type cell wall biogenesis; integral to membrane; mannosyl-oligosaccharide glucosidase activity; oligosaccharide metabolic process; protein N-linked glycosylation,PF03200;PF16923;,,,,,,,,,GCS1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),fungal-type cell wall biogenesis [GO:0009272]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487] comp140157_c0_seq1,2277,38.9548,0.3951835,0,0,,4.00E-66,O80874,"Internal alternative NAD(P)H-ubiquinone oxidoreductase A2, mitochondrial (EC 1.6.5.9) (Internal alternative NADH dehydrogenase NDA2) (NADH:ubiquinone reductase (non-electrogenic) NDA2)","Internal alternative NAD(P)H-ubiquinone oxidoreductase A2, mitochondrial (EC 1.6.5.9) (Internal alternative NADH dehydrogenase NDA2) (NADH:ubiquinone reductase (non-electrogenic) NDA2)",GO:0003959; GO:0050660; GO:0031304; GO:0005759; GO:0005777,NADPH dehydrogenase activity; flavin adenine dinucleotide binding; intrinsic to mitochondrial inner membrane; mitochondrial matrix; peroxisome,PF07992;,4.00E-32,CHOYP_LOC100634472.2.3,,,,,,,NDA2_ARATH,Arabidopsis thaliana (Mouse-ear cress),oxidation-reduction process [GO:0055114] comp140157_c0_seq12,2900,38.0345,0.46870245,0,0,,2.00E-08,O05267,NADH dehydrogenase-like protein YumB (EC 1.6.-.-),NADH dehydrogenase-like protein YumB (EC 1.6.-.-),GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF07992;,,,,,,,,,YUMB_BACSU,Bacillus subtilis (strain 168), comp140157_c0_seq13,2933,37.9475,0.46562082,0,0,,9.00E-40,Q55CD9,Probable NADH dehydrogenase (EC 1.6.-.-),Probable NADH dehydrogenase (EC 1.6.-.-),GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF07992;,,,,,,,,,NDH_DICDI,Dictyostelium discoideum (Slime mold), comp140157_c0_seq14,2959,38.1886,0.46484753,0,0,,4.00E-06,Q10499,Apoptosis-inducing factor 1 (EC 1.-.-.-),Apoptosis-inducing factor 1 (EC 1.-.-.-),GO:0051537; GO:0006915; GO:0045454; GO:0071452; GO:0005829; GO:0050660; GO:0046872; GO:0005741; GO:0005634; GO:0016668,"2 iron, 2 sulfur cluster binding; apoptotic process; cell redox homeostasis; cellular response to singlet oxygen; cytosol; flavin adenine dinucleotide binding; metal ion binding; mitochondrial outer membrane; nucleus; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor",PF07992;PF00355;,,,,,,,,,AIF1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to singlet oxygen [GO:0071452] comp140157_c0_seq16,2310,38.8745,0.39127173,0,0,,4.00E-45,O43090,"Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial (EC 1.6.5.9)","Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial (EC 1.6.5.9)",GO:0003954; GO:0006116; GO:0050660; GO:0006091; GO:0005743,NADH dehydrogenase activity; NADH oxidation; flavin adenine dinucleotide binding; generation of precursor metabolites and energy; mitochondrial inner membrane,PF07992;,,,,,,,,,NDH2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mitochondrial ATP synthesis coupled electron transport [GO:0042775]; NADH oxidation [GO:0006116] comp140157_c0_seq17,2934,38.2754,0.46665824,0,0,,4.00E-77,Q55CD9,Probable NADH dehydrogenase (EC 1.6.-.-),Probable NADH dehydrogenase (EC 1.6.-.-),GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF07992;,1.00E-45,CHOYP_LOC100634472.2.3,,,,,,,NDH_DICDI,Dictyostelium discoideum (Slime mold), comp140157_c0_seq20,1980,38.4848,0.38278882,0,0,,8.00E-54,Q55CD9,Probable NADH dehydrogenase (EC 1.6.-.-),Probable NADH dehydrogenase (EC 1.6.-.-),GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF07992;,6.00E-29,CHOYP_LOC100634472.2.3,,,,,,,NDH_DICDI,Dictyostelium discoideum (Slime mold), comp140157_c0_seq3,2901,38.3661,0.46967662,0,0,,2.00E-72,Q55CD9,Probable NADH dehydrogenase (EC 1.6.-.-),Probable NADH dehydrogenase (EC 1.6.-.-),GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF07992;,,,,,,,,,NDH_DICDI,Dictyostelium discoideum (Slime mold), comp140157_c0_seq7,2013,38.4004,0.37827695,0,0,,,,,,,,,,,3.00E-24,ruditapes_c22226,,,,,,, comp140157_c0_seq8,2992,38.1016,0.46188277,0,0,,4.00E-77,Q55CD9,Probable NADH dehydrogenase (EC 1.6.-.-),Probable NADH dehydrogenase (EC 1.6.-.-),GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF07992;,1.00E-45,CHOYP_LOC100634472.2.3,,,,,,,NDH_DICDI,Dictyostelium discoideum (Slime mold), comp140157_c1_seq1,243,42.7984,0.31242527,5,12,,3.00E-31,Q4V7V8,tRNA-specific adenosine deaminase 2 (EC 3.5.4.-) (Deaminase domain-containing protein 1) (tRNA-specific adenosine-34 deaminase subunit ADAT2),tRNA-specific adenosine deaminase 2 (EC 3.5.4.-) (Deaminase domain-containing protein 1) (tRNA-specific adenosine-34 deaminase subunit ADAT2),GO:0016787; GO:0008033; GO:0008270,hydrolase activity; tRNA processing; zinc ion binding,PF00383;,,,,,,,,,ADAT2_XENLA,Xenopus laevis (African clawed frog),tRNA wobble adenosine to inosine editing [GO:0002100] comp140159_c0_seq1,1432,42.6676,0.64838866,0,0,,4.00E-10,Q62036,5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1),Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1),GO:0030154; GO:0007275; GO:0007283,cell differentiation; multicellular organismal development; spermatogenesis,,,,,,,,,,AZI1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cilium morphogenesis [GO:0060271]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; multicellular organism development [GO:0007275]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of cell proliferation [GO:0008284]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; regulation of centrosome duplication [GO:0010824]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288] comp140159_c0_seq4,2696,44.0282,0.58556441,53,0,,6.00E-53,Q62036,5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1),Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1),GO:0030154; GO:0007275; GO:0007283,cell differentiation; multicellular organismal development; spermatogenesis,,1.00E-140,CHOYP_LOC100374850.2.2,,,,,,,AZI1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cilium morphogenesis [GO:0060271]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; multicellular organism development [GO:0007275]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of cell proliferation [GO:0008284]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; regulation of centrosome duplication [GO:0010824]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288] comp140161_c0_seq1,1841,43.0744,0.31766338,39,13,,4.00E-61,Q63505,General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),GO:0003677; GO:0034735; GO:0006351,"DNA binding; transcription factor TFIIIC2 complex; transcription, DNA-dependent",PF04182;,,,,,,,,,TF3C1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp140161_c0_seq2,3792,43.1698,0.44134513,177,127,,6.00E-46,Q63505,General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),GO:0003677; GO:0034735; GO:0006351,"DNA binding; transcription factor TFIIIC2 complex; transcription, DNA-dependent",PF04182;,,,,,,,,,TF3C1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp140164_c0_seq1,2890,39.5848,0.4101563,336,2555,,1.00E-14,B2GAI0,60 kDa chaperonin (GroEL protein) (Protein Cpn60),60 kDa chaperonin (GroEL protein) (Protein Cpn60),GO:0005524; GO:0005737; GO:0042026,ATP binding; cytoplasm; protein refolding,PF00118;,,,,,,,,,CH60_LACF3,Lactobacillus fermentum (strain NBRC 3956 / LMG 18251),protein refolding [GO:0042026] comp140164_c0_seq2,2871,39.4984,0.38724968,147,1351,,0,Q5ZJK8,T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta),T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta),GO:0005524; GO:0007339; GO:0005832; GO:0005874; GO:0005739; GO:0006457; GO:0002199,ATP binding; binding of sperm to zona pellucida; chaperonin-containing T-complex; microtubule; mitochondrion; protein folding; zona pellucida receptor complex,PF00118;,0,CHOYP_TCPH.1.1,3.00E-89,ruditapes_c15412,,,,,TCPH_CHICK,Gallus gallus (Chicken),binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; toxin transport [GO:1901998] comp140166_c0_seq1,675,38.2222,0.48985615,8,1,,3.00E-07,O75123,Zinc finger protein 623,Zinc finger protein 623,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN623_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140166_c0_seq10,568,39.7887,0.31391964,19,44,,2.00E-09,Q505G8,Zinc finger protein 827,Zinc finger protein 827,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN827_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140166_c0_seq11,276,36.5942,0.32665523,16,0,,1.00E-12,Q6P560,Zinc finger protein 182 (Zinc finger protein 21),Zinc finger protein 182 (Zinc finger protein 21),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN182_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140166_c0_seq4,1392,38.9368,0.41874723,9,57,,8.00E-10,Q9NSJ1,Putative zinc finger protein 355P (Zinc finger protein ZnFP01),Putative zinc finger protein 355P (Zinc finger protein ZnFP01),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,Z355P_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140166_c0_seq7,402,40.796,0.30128775,1,11,,4.00E-13,B7ZRM8,MDS1 and EVI1 complex locus protein EVI1-B (Ecotropic virus integration site 1 protein homolog-B),MDS1 and EVI1 complex locus protein EVI1-B (Ecotropic virus integration site 1 protein homolog-B),GO:0003677; GO:0046872; GO:0016607; GO:0039013; GO:0039022; GO:0072196; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nuclear speck; pronephric distal tubule morphogenesis; pronephric duct development; proximal/distal pattern formation involved in pronephric nephron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,EVI1B_XENLA,Xenopus laevis (African clawed frog),"pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140166_c0_seq8,817,36.7197,0.47517833,28,23,,3.00E-09,Q2M3W8,Zinc finger protein 181 (HHZ181),Zinc finger protein 181 (HHZ181),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN181_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140166_c0_seq9,451,41.6851,0.51299764,0,4,,3.00E-09,P59923,Zinc finger protein 445 (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15),Zinc finger protein 445 (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF13912;,,,,,,,,,ZN445_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp140168_c0_seq2,1329,33.4838,0.64714983,68,534,,5.00E-21,Q17754,Mitochondrial import inner membrane translocase subunit Tim9,Mitochondrial import inner membrane translocase subunit Tim9,GO:0046872; GO:0005743; GO:0045039; GO:0040014; GO:0000003,metal ion binding; mitochondrial inner membrane; protein import into mitochondrial inner membrane; regulation of multicellular organism growth; reproduction,PF02953;,3.00E-12,CHOYP_LOC101071791.1.1,,,,,,,TIM9_CAEEL,Caenorhabditis elegans,chaperone-mediated protein transport [GO:0072321]; protein import into mitochondrial inner membrane [GO:0045039]; regulation of multicellular organism growth [GO:0040014]; reproduction [GO:0000003] comp140169_c0_seq2,916,35.6987,0.63823446,11,64,,4.00E-11,Q9WVA1,Mitochondrial import inner membrane translocase subunit Tim8 A (Deafness dystonia protein 1 homolog),Mitochondrial import inner membrane translocase subunit Tim8 A (Deafness dystonia protein 1 homolog),GO:0005743; GO:0006626; GO:0008270,mitochondrial inner membrane; protein targeting to mitochondrion; zinc ion binding,PF02953;,,,8.00E-15,ruditapes2_c1895,,,,,TIM8A_RAT,Rattus norvegicus (Rat),protein targeting to mitochondrion [GO:0006626] comp140170_c0_seq1,2289,40.1485,0.40837679,25,504,,0,Q96KP4,Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A),Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Carnosine dipeptidase II) (Epididymis secretory protein Li 13) (Glutamate carboxypeptidase-like protein 1) (Peptidase A),GO:0004180; GO:0005829; GO:0016805; GO:0006750; GO:1901687; GO:0046872; GO:0008237; GO:0006508; GO:0000096; GO:0034701; GO:0006805,carboxypeptidase activity; cytosol; dipeptidase activity; glutathione biosynthetic process; glutathione derivative biosynthetic process; metal ion binding; metallopeptidase activity; proteolysis; sulfur amino acid metabolic process; tripeptidase activity; xenobiotic metabolic process,PF07687;PF01546;,,,,,,,,,CNDP2_HUMAN,Homo sapiens (Human),glutathione biosynthetic process [GO:0006750]; peptide catabolic process [GO:0043171]; sulfur amino acid metabolic process [GO:0000096] comp140170_c0_seq2,2272,40.1849,0.41007683,42,407,,0,Q96KP4,Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A),Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Carnosine dipeptidase II) (Epididymis secretory protein Li 13) (Glutamate carboxypeptidase-like protein 1) (Peptidase A),GO:0004180; GO:0005829; GO:0016805; GO:0006750; GO:1901687; GO:0046872; GO:0008237; GO:0006508; GO:0000096; GO:0034701; GO:0006805,carboxypeptidase activity; cytosol; dipeptidase activity; glutathione biosynthetic process; glutathione derivative biosynthetic process; metal ion binding; metallopeptidase activity; proteolysis; sulfur amino acid metabolic process; tripeptidase activity; xenobiotic metabolic process,PF07687;PF01546;,0,CHOYP_CNDP2.3.4,,,,,,,CNDP2_HUMAN,Homo sapiens (Human),glutathione biosynthetic process [GO:0006750]; peptide catabolic process [GO:0043171]; sulfur amino acid metabolic process [GO:0000096] comp140171_c0_seq1,2928,43.5792,0.53633014,0,31,,1.00E-21,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp140171_c0_seq4,3421,42.3268,0.53233087,29,25,,0,P25635,Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1),Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1),GO:0034388; GO:0007109; GO:0005737; GO:0000480; GO:0000447; GO:0000472; GO:0030010; GO:0032040; GO:0030515,"Pwp2p-containing subcomplex of 90S preribosome; cytokinesis, completion of separation; cytoplasm; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); establishment of cell polarity; small-subunit processome; snoRNA binding",PF04003;PF00400;,0,CHOYP_PWP2.1.1,,,,,,,PWP2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"cell separation after cytokinesis [GO:0000920]; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; establishment of cell polarity [GO:0030010]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]; rRNA methylation [GO:0031167]" comp140171_c0_seq5,3489,42.0751,0.51555109,0,0,,0,Q5RFQ3,Periodic tryptophan protein 2 homolog,Periodic tryptophan protein 2 homolog,GO:0005730,nucleolus,PF04003;PF00400;,0,CHOYP_PWP2.1.1,1.00E-12,ruditapes_c17542,,,,,PWP2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140175_c0_seq1,1894,42.661,0.51469859,112,522,,0,Q3ULD5,"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)","Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)",GO:0005524; GO:0015936; GO:0006552; GO:0004485; GO:0005759; GO:0005739,ATP binding; coenzyme A metabolic process; leucine catabolic process; methylcrotonoyl-CoA carboxylase activity; mitochondrial matrix; mitochondrion,PF01039;,0,CHOYP_BRAFLDRAFT_266349.1.1,,,,,,,MCCB_MOUSE,Mus musculus (Mouse),coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552] comp140177_c0_seq1,2099,44.9738,0.35883885,0,0,,,,,,,,,3.00E-84,CHOYP_LOC100651327.1.1,,,,,,,,, comp140177_c0_seq2,3401,46.6627,0.4290956,0,0,,0,Q7TPH6,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0042177; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; negative regulation of protein catabolic process; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,0,CHOYP_MYCB2.1.2,,,,,,,MYCB2_MOUSE,Mus musculus (Mouse),"branchiomotor neuron axon guidance [GO:0021785]; cell morphogenesis involved in neuron differentiation [GO:0048667]; central nervous system projection neuron axonogenesis [GO:0021952]; motor neuron axon guidance [GO:0008045]; negative regulation of protein catabolic process [GO:0042177]; protein ubiquitination [GO:0016567]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140177_c0_seq3,2042,45.1518,0.34634954,0,0,,,,,,,,,3.00E-84,CHOYP_LOC100651327.1.1,,,,,,,,, comp140177_c0_seq5,4443,46.8602,0.39953659,0,0,,0,O75592,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,0,CHOYP_MYCB2.1.2,,,,,,,MYCB2_HUMAN,Homo sapiens (Human),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140177_c0_seq6,1698,45.4064,0.3325797,0,0,,2.00E-147,Q7TPH6,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0042177; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; negative regulation of protein catabolic process; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,,,,,,,,,MYCB2_MOUSE,Mus musculus (Mouse),"branchiomotor neuron axon guidance [GO:0021785]; cell morphogenesis involved in neuron differentiation [GO:0048667]; central nervous system projection neuron axonogenesis [GO:0021952]; motor neuron axon guidance [GO:0008045]; negative regulation of protein catabolic process [GO:0042177]; protein ubiquitination [GO:0016567]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140177_c0_seq9,2740,46.2044,0.32238993,0,0,,0,O75592,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,,,,,,,,,MYCB2_HUMAN,Homo sapiens (Human),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140178_c0_seq1,1966,43.3367,0.42305285,0,0,,3.00E-16,Q6DRL4,"Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)","Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)",GO:0006281; GO:0006260; GO:0003682; GO:0001731; GO:0033314; GO:0007095; GO:0005634; GO:0030174; GO:0010212,DNA repair; DNA replication; chromatin binding; formation of translation preinitiation complex; mitotic DNA replication checkpoint; mitotic G2 DNA damage checkpoint; nucleus; regulation of DNA-dependent DNA replication initiation; response to ionizing radiation,PF15292;,,,,,,,,,TICRR_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle checkpoint [GO:0000075]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; formation of translation preinitiation complex [GO:0001731]; mitotic cell cycle checkpoint [GO:0007093]; mitotic DNA replication checkpoint [GO:0033314]; mitotic G2 DNA damage checkpoint [GO:0007095]; regulation of DNA-dependent DNA replication initiation [GO:0030174]; response to ionizing radiation [GO:0010212] comp140178_c0_seq2,3490,41.3467,0.37601751,95,165,,5.00E-18,Q7Z2Z1,"Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)","Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)",GO:0006281; GO:0006260; GO:0003682; GO:0001731; GO:0033314; GO:0005634; GO:0030174; GO:0010212,DNA repair; DNA replication; chromatin binding; formation of translation preinitiation complex; mitotic DNA replication checkpoint; nucleus; regulation of DNA-dependent DNA replication initiation; response to ionizing radiation,PF15292;,,,,,,,,,TICRR_HUMAN,Homo sapiens (Human),cell cycle checkpoint [GO:0000075]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; formation of translation preinitiation complex [GO:0001731]; mitotic DNA replication checkpoint [GO:0033314]; regulation of DNA-dependent DNA replication initiation [GO:0030174]; response to ionizing radiation [GO:0010212] comp140180_c0_seq1,997,41.1234,0.60340093,80,234,,2.00E-12,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140180_c0_seq2,2424,38.1601,0.6415345,0,3,,5.00E-31,Q9UII5,Zinc finger protein 107 (Zinc finger protein 588) (Zinc finger protein ZFD25),Zinc finger protein 107 (Zinc finger protein 588) (Zinc finger protein ZFD25),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN107_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140180_c0_seq3,2968,37.3989,0.56599672,22,114,,4.00E-29,A6NN14,Zinc finger protein 729,Zinc finger protein 729,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN729_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140182_c3_seq1,3294,44.2623,0.36717406,3,0,,8.00E-46,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp140182_c3_seq2,1232,44.9675,0.38483171,2,0,,1.00E-07,Q6NXD8,DENN domain-containing protein 5B (Rab6IP1-like protein),DENN domain-containing protein 5B (Rab6IP1-like protein),GO:0017112; GO:0016021,Rab guanyl-nucleotide exchange factor activity; integral to membrane,PF03455;PF02141;PF01477;PF02759;PF03456;,,,,,,,,,DEN5B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),detection of mechanical stimulus [GO:0050982] comp140182_c3_seq3,2015,44.665,0.34807577,170,25,,1.00E-50,Q8IVV2,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,3.00E-14,CHOYP_BRAFLDRAFT_67580.2.2,,,,,,,LOXH1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp140182_c3_seq7,689,47.3149,0.36758068,52,0,,3.00E-22,Q8IVV2,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp140184_c0_seq1,4273,32.1554,0.39029479,0,0,,1.00E-42,Q8N9W6,Protein boule-like,Protein boule-like,GO:0003723; GO:0030154; GO:0005737; GO:0007126; GO:0007275; GO:0000166; GO:0045948; GO:0007283; GO:0008494,RNA binding; cell differentiation; cytoplasm; meiosis; multicellular organismal development; nucleotide binding; positive regulation of translational initiation; spermatogenesis; translation activator activity,PF00076;,,,,,,,,,BOLL_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283] comp140184_c0_seq5,1176,39.7959,0.38698039,0,0,,6.00E-09,Q5RBU8,Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1),Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0005654; GO:0000166; GO:0030529; GO:0005681,RNA binding; RNA splicing; cytoplasm; mRNA processing; nucleoplasm; nucleotide binding; ribonucleoprotein complex; spliceosomal complex,PF00076;,,,,,,,,,ROA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"miRNA transport [GO:1990428]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; primary miRNA processing [GO:0031053]" comp140184_c0_seq6,4324,32.2155,0.38415064,0,0,,1.00E-41,Q8N9W6,Protein boule-like,Protein boule-like,GO:0003723; GO:0030154; GO:0005737; GO:0007126; GO:0007275; GO:0000166; GO:0045948; GO:0007283; GO:0008494,RNA binding; cell differentiation; cytoplasm; meiosis; multicellular organismal development; nucleotide binding; positive regulation of translational initiation; spermatogenesis; translation activator activity,PF00076;,,,,,,,,,BOLL_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283] comp140184_c0_seq7,4336,32.2648,0.38206759,0,0,,8.00E-22,Q95192,Deleted in azoospermia-like (DAZ-like autosomal) (Deleted in azoospermia-like 1),Deleted in azoospermia-like (DAZ-like autosomal) (Deleted in azoospermia-like 1),GO:0003723; GO:0030154; GO:0005737; GO:0007275; GO:0000166; GO:0005634; GO:0006417; GO:0007283,RNA binding; cell differentiation; cytoplasm; multicellular organismal development; nucleotide binding; nucleus; regulation of translation; spermatogenesis,PF00076;,,,,,,,,,DAZL_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; spermatogenesis [GO:0007283] comp140184_c0_seq8,1164,39.6907,0.39324924,0,0,,2.00E-44,Q8N9W6,Protein boule-like,Protein boule-like,GO:0003723; GO:0030154; GO:0005737; GO:0007126; GO:0007275; GO:0000166; GO:0045948; GO:0007283; GO:0008494,RNA binding; cell differentiation; cytoplasm; meiosis; multicellular organismal development; nucleotide binding; positive regulation of translational initiation; spermatogenesis; translation activator activity,PF00076;,,,,,,,,,BOLL_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283] comp140184_c0_seq9,4285,32.2054,0.38815598,0,0,,5.00E-22,Q9BGN8,Deleted in azoospermia-like (DAZ-like autosomal) (Deleted in azoospermia-like 1),Deleted in azoospermia-like (DAZ-like autosomal) (Deleted in azoospermia-like 1),GO:0003723; GO:0030154; GO:0005737; GO:0007275; GO:0000166; GO:0005634; GO:0006417; GO:0007283,RNA binding; cell differentiation; cytoplasm; multicellular organismal development; nucleotide binding; nucleus; regulation of translation; spermatogenesis,PF00076;,,,,,,,,,DAZL_CALJA,Callithrix jacchus (White-tufted-ear marmoset),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; spermatogenesis [GO:0007283] comp140185_c0_seq1,1797,39.4546,0.31994519,0,0,,3.00E-52,P42696,RNA-binding protein 34 (RNA-binding motif protein 34),RNA-binding protein 34 (RNA-binding motif protein 34),GO:0003723; GO:0005730; GO:0000166,RNA binding; nucleolus; nucleotide binding,PF00076;,,,,,,,,,RBM34_HUMAN,Homo sapiens (Human), comp140187_c0_seq1,964,37.8631,0.65699148,89,337,,1.00E-61,Q6QD59,Vesicle transport protein SEC20,Vesicle transport protein SEC20,GO:0000139; GO:0031201; GO:0006915; GO:0006914; GO:0005783; GO:0005789; GO:0016320; GO:0007029; GO:0016021; GO:0005739; GO:0005635; GO:0015031; GO:0016192,Golgi membrane; SNARE complex; apoptotic process; autophagy; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum membrane fusion; endoplasmic reticulum organization; integral to membrane; mitochondrion; nuclear envelope; protein transport; vesicle-mediated transport,PF03908;,,,,,,,,,SEC20_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; autophagy [GO:0006914]; endoplasmic reticulum membrane fusion [GO:0016320]; endoplasmic reticulum organization [GO:0007029]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp140188_c0_seq2,2221,42.9086,0.55929745,0,21,,,,,,,,,3.00E-115,CHOYP_RLA0.5.7,,,,,,,,, comp140188_c0_seq3,1502,44.0746,0.61859799,0,0,,,,,,,,,,,1.00E-20,ruditapes_c14169,,,,,,, comp140190_c0_seq1,3078,36.2248,1.01754135,366,2436,,8.00E-09,Q66IT9,Immediate early response gene 5-like protein,Immediate early response gene 5-like protein,,,PF05760;,9.00E-23,CHOYP_LOC584505.1.1,2.00E-47,ruditapes_c24741,,,,,IER5L_XENLA,Xenopus laevis (African clawed frog), comp140192_c0_seq1,1408,35.5114,0.50273303,1143,6291,,2.00E-82,P12815,Programmed cell death protein 6 (ALG-257) (PMP41) (Probable calcium-binding protein ALG-2),Programmed cell death protein 6 (ALG-257) (PMP41) (Probable calcium-binding protein ALG-2),GO:0006919; GO:0001525; GO:0060090; GO:0005509; GO:0033554; GO:0005737; GO:0031410; GO:0005789; GO:0005768; GO:0006886; GO:0032007; GO:0051898; GO:0030948; GO:0031965; GO:0045766; GO:0010595; GO:0001938; GO:0051592; GO:0036324,"activation of cysteine-type endopeptidase activity involved in apoptotic process; angiogenesis; binding, bridging; calcium ion binding; cellular response to stress; cytoplasm; cytoplasmic vesicle; endoplasmic reticulum membrane; endosome; intracellular protein transport; negative regulation of TOR signaling cascade; negative regulation of protein kinase B signaling cascade; negative regulation of vascular endothelial growth factor receptor signaling pathway; nuclear membrane; positive regulation of angiogenesis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; response to calcium ion; vascular endothelial growth factor receptor-2 signaling pathway",PF13202;PF13499;,4.00E-87,CHOYP_BRAFLDRAFT_280861.2.2,2.00E-18,ruditapes_c1980,,,,,PDCD6_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] comp140194_c1_seq1,798,36.5915,0.45192379,18,35,,,,,,,,,,,1.00E-11,ruditapes2_c3038,,,,,,, comp140194_c1_seq5,398,39.9497,0.44404096,0,0,,,,,,,,,,,6.00E-12,ruditapes_c22652,,,,,,, comp140195_c0_seq1,822,33.6983,0.4352201,60,109,,5.00E-08,P17571,Nitrate reductase [NADH] (NR) (EC 1.7.1.1) (Fragment),Nitrate reductase [NADH] (NR) (EC 1.7.1.1) (Fragment),GO:0009055; GO:0020037; GO:0030151; GO:0042128; GO:0009703,electron carrier activity; heme binding; molybdenum ion binding; nitrate assimilation; nitrate reductase (NADH) activity,PF00173;PF00970;PF03404;PF00175;PF00174;,,,,,,,,,NIA1_MAIZE,Zea mays (Maize),nitrate assimilation [GO:0042128] comp140195_c0_seq2,1483,45.0438,0.64735795,139,161,,3.00E-134,Q9VWP4,"Probable sulfite oxidase, mitochondrial (EC 1.8.3.1)","Probable sulfite oxidase, mitochondrial (EC 1.8.3.1)",GO:0009055; GO:0020037; GO:0005758; GO:0030151; GO:0030163; GO:0008482; GO:0006790,electron carrier activity; heme binding; mitochondrial intermembrane space; molybdenum ion binding; protein catabolic process; sulfite oxidase activity; sulfur compound metabolic process,PF00173;PF03404;PF00174;,9.00E-76,CHOYP_SUOX.1.1,,,,,,,SUOX_DROME,Drosophila melanogaster (Fruit fly),nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790] comp140196_c0_seq1,2000,35.45,0.93634451,17,249,,3.00E-12,O35516,Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],GO:0007219; GO:0060413; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0061073; GO:0005829; GO:0030326; GO:0005576; GO:0072104; GO:0072015; GO:0001947; GO:0006959; GO:0001701; GO:0002437; GO:0005887; GO:0072602; GO:0070986; GO:0002011; GO:0008285; GO:0000122; GO:0005654; GO:0060674; GO:0030513; GO:0046579; GO:0043065; GO:0008284; GO:0045672; GO:0072014; GO:0006351; GO:0042060,"Notch signaling pathway; atrial septum morphogenesis; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; ciliary body morphogenesis; cytosol; embryonic limb morphogenesis; extracellular region; glomerular capillary formation; glomerular visceral epithelial cell development; heart looping; humoral immune response; in utero embryonic development; inflammatory response to antigenic stimulus; integral to plasma membrane; interleukin-4 secretion; left/right axis specification; morphogenesis of an epithelial sheet; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; placenta blood vessel development; positive regulation of BMP signaling pathway; positive regulation of Ras protein signal transduction; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of osteoclast differentiation; proximal tubule development; transcription, DNA-dependent; wound healing",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_MOUSE,Mus musculus (Mouse),"atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]" comp140196_c0_seq2,1985,35.5164,0.94004953,10,104,,3.00E-10,P31695,Neurogenic locus notch homolog protein 4 (Notch 4) [Cleaved into: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain],Neurogenic locus notch homolog protein 4 (Notch 4) [Cleaved into: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain],GO:0007219; GO:0005509; GO:0030154; GO:0009986; GO:0009790; GO:0016021; GO:0045602; GO:0005634; GO:0001569; GO:0005886; GO:0006355; GO:0006351,"Notch signaling pathway; calcium ion binding; cell differentiation; cell surface; embryo development; integral to membrane; negative regulation of endothelial cell differentiation; nucleus; patterning of blood vessels; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12796;PF00008;PF07645;PF12661;PF07684;PF00066;,,,,,,,,,NOTC4_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; embryo development [GO:0009790]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of Notch signaling pathway [GO:0045746]; Notch signaling pathway [GO:0007219]; patterning of blood vessels [GO:0001569]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aorta morphogenesis [GO:1903849]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein localization [GO:0032880]; regulation of protein processing [GO:0070613]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; venous blood vessel morphogenesis [GO:0048845]" comp140198_c0_seq1,2014,39.9702,0.90468077,309,0,male,7.00E-26,Q497Q6,Protein FAM228B,Protein FAM228B,,,,4.00E-57,CHOYP_LOC100372845.3.3,,,,,,,F228B_MOUSE,Mus musculus (Mouse), comp140198_c0_seq2,2115,40.3783,0.91832122,359,5,,,,,,,,,2.00E-36,CHOYP_LOC100372845.1.3,,,,,,,,, comp140204_c0_seq1,566,49.1166,0.98143501,0,30,,1.00E-58,Q91766,Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1),Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,HNF4A_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp140204_c0_seq3,414,48.3092,1.00820509,2,0,,2.00E-61,P41235,Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4),Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4),GO:0001102; GO:0001077; GO:0003705; GO:0060395; GO:0007596; GO:0005737; GO:0031018; GO:0005504; GO:0042593; GO:0030522; GO:0004879; GO:0006629; GO:0030308; GO:0008285; GO:0005654; GO:0006591; GO:0055091; GO:2000189; GO:0042803; GO:0005102; GO:0010470; GO:0060398; GO:0050796; GO:0019216; GO:0009749; GO:0043565; GO:0007548; GO:0023019; GO:0003707; GO:0006367; GO:0044212; GO:0070328; GO:0006805; GO:0008270,RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; SMAD protein signal transduction; blood coagulation; cytoplasm; endocrine pancreas development; fatty acid binding; glucose homeostasis; intracellular receptor signaling pathway; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; lipid metabolic process; negative regulation of cell growth; negative regulation of cell proliferation; nucleoplasm; ornithine metabolic process; phospholipid homeostasis; positive regulation of cholesterol homeostasis; protein homodimerization activity; receptor binding; regulation of gastrulation; regulation of growth hormone receptor signaling pathway; regulation of insulin secretion; regulation of lipid metabolic process; response to glucose stimulus; sequence-specific DNA binding; sex differentiation; signal transduction involved in regulation of gene expression; steroid hormone receptor activity; transcription initiation from RNA polymerase II promoter; transcription regulatory region DNA binding; triglyceride homeostasis; xenobiotic metabolic process; zinc ion binding,PF00104;PF00105;,,,,,,,,,HNF4A_HUMAN,Homo sapiens (Human),"acyl-CoA metabolic process [GO:0006637]; blood coagulation [GO:0007596]; cell-cell junction organization [GO:0045216]; cell differentiation [GO:0030154]; establishment of tissue polarity [GO:0007164]; glucose homeostasis [GO:0042593]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; negative regulation of activation of JAK2 kinase activity [GO:1902569]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; ornithine metabolic process [GO:0006591]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol homeostasis [GO:2000189]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gastrulation [GO:0010470]; regulation of growth hormone receptor signaling pathway [GO:0060398]; regulation of insulin secretion [GO:0050796]; regulation of lipid metabolic process [GO:0019216]; regulation of microvillus assembly [GO:0032534]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucose [GO:0009749]; sex differentiation [GO:0007548]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein signal transduction [GO:0060395]; transcription initiation from RNA polymerase II promoter [GO:0006367]; triglyceride homeostasis [GO:0070328]; xenobiotic metabolic process [GO:0006805]" comp140204_c2_seq6,1948,39.0144,0.86384687,2,10,,3.00E-107,Q91766,Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1),Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,4.00E-94,CHOYP_LOC100023660.1.1,,,,,,,HNF4A_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp140205_c0_seq1,1339,39.4324,0.92419156,43,232,,2.00E-60,P52014,Peptidyl-prolyl cis-trans isomerase 6 (PPIase 6) (EC 5.2.1.8) (Cyclophilin-6) (Rotamase 6),Peptidyl-prolyl cis-trans isomerase 6 (PPIase 6) (EC 5.2.1.8) (Cyclophilin-6) (Rotamase 6),GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,1.00E-22,CHOYP_PPIB.4.4,2.00E-49,ruditapes_c4268,,,,,CYP6_CAEEL,Caenorhabditis elegans,protein folding [GO:0006457] comp140205_c0_seq2,1360,39.4853,0.92621088,13,157,,8.00E-59,Q27774,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin),GO:0005788; GO:0042277; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum lumen; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,3.00E-24,CHOYP_NEMVEDRAFT_V1G191841.1.1,,,,,,,PPIB_SCHJA,Schistosoma japonicum (Blood fluke),protein folding [GO:0006457] comp140206_c0_seq1,1373,37.7276,0.34853862,53,129,,2.00E-20,C3M9C2,"Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)","Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)",GO:0052908; GO:0003723; GO:0005737; GO:0000179; GO:0031167,"16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity; RNA binding; cytoplasm; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation",PF00398;,,,,,,,,,RSMA_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234), comp140206_c0_seq2,1352,37.7959,0.35293866,29,108,,1.00E-152,Q9D0D4,"Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase)","Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase)",GO:0052909; GO:0003723; GO:0005730; GO:0000179; GO:0031167,"18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity; RNA binding; nucleolus; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation",PF00398;,1.00E-169,CHOYP_BRAFLDRAFT_225323.1.1,,,,,,,DIM1_MOUSE,Mus musculus (Mouse), comp140210_c0_seq1,2558,45.9734,1.02235555,6173,0,,7.00E-46,F1MBP6,Kelch-like protein 3,Kelch-like protein 3,GO:0031463; GO:0005856; GO:0005829; GO:0072156; GO:0050801; GO:0070936; GO:0042787; GO:0070294,Cul3-RING ubiquitin ligase complex; cytoskeleton; cytosol; distal tubule morphogenesis; ion homeostasis; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; renal sodium ion absorption,PF07707;PF00651;PF01344;,,,,,,,,,KLHL3_BOVIN,Bos taurus (Bovine),distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294] comp140212_c0_seq1,1728,45.1389,0.36400012,192,1042,,7.00E-101,Q6GPP7,Transmembrane protein 209,Transmembrane protein 209,GO:0016021,integral to membrane,PF09786;,2.00E-60,CHOYP_LOC100377657.1.1,,,,,,,TM209_XENLA,Xenopus laevis (African clawed frog), comp140213_c2_seq2,1842,45.2769,0.81999784,0,4,,6.00E-11,Q8NCX0,Coiled-coil domain-containing protein 150,Coiled-coil domain-containing protein 150,,,,,,,,,,,,CC150_HUMAN,Homo sapiens (Human), comp140213_c2_seq5,1286,43.6236,0.81755199,5,0,,6.00E-11,Q8NCX0,Coiled-coil domain-containing protein 150,Coiled-coil domain-containing protein 150,,,,,,,,,,,,CC150_HUMAN,Homo sapiens (Human), comp140216_c0_seq1,904,37.8319,0.51816131,78,566,,2.00E-15,Q5ZJ97,Uncharacterized protein KIAA1143 homolog,Uncharacterized protein KIAA1143 homolog,,,PF15377;,,,,,,,,,K1143_CHICK,Gallus gallus (Chicken), comp140219_c1_seq1,2997,39.0724,0.51977692,282,1119,,2.00E-34,Q9P1Y6,PHD and RING finger domain-containing protein 1,PHD and RING finger domain-containing protein 1,GO:0070063; GO:0006397; GO:0006366; GO:0008270,RNA polymerase binding; mRNA processing; transcription from RNA polymerase II promoter; zinc ion binding,PF00628;PF13639;,8.00E-36,CHOYP_LOC100476601.1.1,,,,,,,PHRF1_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; transcription from RNA polymerase II promoter [GO:0006366] comp14021_c0_seq1,233,42.9185,0.65626209,3,0,,2.00E-22,P79098,Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp140220_c0_seq1,1391,41.4809,0.47322819,54,650,,9.00E-145,Q8BGA5,KRR1 small subunit processome component homolog (HIV-1 Rev-binding protein 2 homolog) (KRR-R motif-containing protein 1),KRR1 small subunit processome component homolog (HIV-1 Rev-binding protein 2 homolog) (KRR-R motif-containing protein 1),GO:0003723; GO:0005730; GO:0006364; GO:0030529,RNA binding; nucleolus; rRNA processing; ribonucleoprotein complex,,1.00E-155,CHOYP_KRR1.1.1,,,,,,,KRR1_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp140222_c0_seq1,2096,33.6355,0.38947488,231,494,,,,,,,,,9.00E-21,CHOYP_ISCW_ISCW018425.1.1,,,,,,,,, comp140222_c0_seq2,2117,33.3018,0.41047847,530,669,,2.00E-49,P52555,Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 31) (ERp31),Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 31) (ERp31),GO:0005788; GO:0006886; GO:0042470; GO:0006457; GO:0009306; GO:0006950; GO:0005790; GO:0030133,endoplasmic reticulum lumen; intracellular protein transport; melanosome; protein folding; protein secretion; response to stress; smooth endoplasmic reticulum; transport vesicle,PF07749;PF07912;,,,,,,,,,ERP29_RAT,Rattus norvegicus (Rat),activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976] comp140224_c0_seq1,1961,33.1464,0.46921647,116,278,,3.00E-40,Q9CZY3,Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1),Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1),GO:0035370; GO:0016881; GO:0042275; GO:0005634; GO:0070534; GO:0000151,UBC13-UEV1A complex; acid-amino acid ligase activity; error-free postreplication DNA repair; nucleus; protein K63-linked ubiquitination; ubiquitin ligase complex,PF00179;,,,,,,,,,UB2V1_MOUSE,Mus musculus (Mouse),error-free postreplication DNA repair [GO:0042275]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534] comp140226_c0_seq1,2026,30.9477,0.37315915,3351,7367,,3.00E-70,Q9H1K1,"Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (NifU-like N-terminal domain-containing protein) (NifU-like protein)","Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (NifU-like N-terminal domain-containing protein) (NifU-like protein)",GO:0005829; GO:0005506; GO:0016226; GO:0051536; GO:0005759; GO:0009399; GO:0005634; GO:0032947; GO:0044281,cytosol; iron ion binding; iron-sulfur cluster assembly; iron-sulfur cluster binding; mitochondrial matrix; nitrogen fixation; nucleus; protein complex scaffold; small molecule metabolic process,PF01592;,6.00E-86,CHOYP_ISCU.1.1,2.00E-82,ruditapes_c19772,,,,,ISCU_HUMAN,Homo sapiens (Human),[2Fe-2S] cluster assembly [GO:0044571]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; nitrogen fixation [GO:0009399]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; small molecule metabolic process [GO:0044281] comp140228_c0_seq1,2482,39.444,0.39440712,140,775,,9.00E-18,Q1LUQ4,Major facilitator superfamily domain-containing protein 6-A (Macrophage MHC class I receptor 2 homolog A),Major facilitator superfamily domain-containing protein 6-A (Macrophage MHC class I receptor 2 homolog A),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF12832;,,,,,,,,,MFD6A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140230_c0_seq4,2048,39.0625,0.38581767,53,275,,8.00E-31,P34152,Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK),Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK),GO:0005524; GO:0001525; GO:0016324; GO:0021955; GO:0005829; GO:0043542; GO:0048013; GO:0040023; GO:0030198; GO:0005925; GO:0007229; GO:0030027; GO:0000226; GO:0005815; GO:0043066; GO:0050771; GO:0046621; GO:0051964; GO:0001764; GO:0004715; GO:0005634; GO:0048471; GO:0030335; GO:0008284; GO:0014068; GO:0051897; GO:0045860; GO:2000060; GO:0046777; GO:0033628; GO:0008360; GO:0045667; GO:0007172; GO:0004871; GO:0001570,ATP binding; angiogenesis; apical plasma membrane; central nervous system neuron axonogenesis; cytosol; endothelial cell migration; ephrin receptor signaling pathway; establishment of nucleus localization; extracellular matrix organization; focal adhesion; integrin-mediated signaling pathway; lamellipodium; microtubule cytoskeleton organization; microtubule organizing center; negative regulation of apoptotic process; negative regulation of axonogenesis; negative regulation of organ growth; negative regulation of synapse assembly; neuron migration; non-membrane spanning protein tyrosine kinase activity; nucleus; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of protein kinase activity; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein autophosphorylation; regulation of cell adhesion mediated by integrin; regulation of cell shape; regulation of osteoblast differentiation; signal complex assembly; signal transducer activity; vasculogenesis,PF00373;PF03623;PF07714;,7.00E-16,CHOYP_LOC100876637.1.2,,,,,,,FAK1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; axon guidance [GO:0007411]; blood vessel development [GO:0001568]; cell adhesion [GO:0007155]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of nucleus localization [GO:0040023]; extracellular matrix organization [GO:0030198]; growth hormone receptor signaling pathway [GO:0060396]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570] comp140235_c0_seq1,1202,43.2612,0.45801384,13,6,,2.00E-67,Q90941,Protein polybromo-1,Protein polybromo-1,GO:0003677; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,,,,,,,,,PB1_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140235_c0_seq2,1095,44.3836,0.49280617,2,0,,1.00E-15,P25439,ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma),ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma),GO:0005524; GO:0043044; GO:0016887; GO:0003677; GO:0007409; GO:0035060; GO:0070983; GO:0004386; GO:0035172; GO:0043974; GO:0007480; GO:0008587; GO:0008586; GO:0007474; GO:0007517; GO:2000134; GO:0048477; GO:0006909; GO:0045742; GO:0045893; GO:0006351,"ATP binding; ATP-dependent chromatin remodeling; ATPase activity; DNA binding; axonogenesis; brahma complex; dendrite guidance; helicase activity; hemocyte proliferation; histone H3-K27 acetylation; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; muscle organ development; negative regulation of G1/S transition of mitotic cell cycle; oogenesis; phagocytosis; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;,,,,,,,,,BRM_DROME,Drosophila melanogaster (Fruit fly),"ATP-dependent chromatin remodeling [GO:0043044]; axonogenesis [GO:0007409]; chromatin-mediated maintenance of transcription [GO:0048096]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; hemocyte proliferation [GO:0035172]; hippo signaling [GO:0035329]; histone H3-K27 acetylation [GO:0043974]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; muscle organ development [GO:0007517]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuroblast proliferation [GO:0007406]; neurogenesis [GO:0022008]; neuron development [GO:0048666]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of innate immune response [GO:0045088]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp140235_c0_seq3,1247,43.7049,0.48289236,17,0,,3.00E-10,Q3TKT4,Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),GO:0005524; GO:0016887; GO:0010424; GO:0008094; GO:0000977; GO:0001105; GO:0016514; GO:0071778; GO:0035887; GO:0001832; GO:0001835; GO:0000902; GO:0003682; GO:0006338; GO:0060318; GO:0035116; GO:0048562; GO:0048730; GO:0030198; GO:0030900; GO:0007403; GO:0060347; GO:0004386; GO:0000792; GO:0030902; GO:0043966; GO:0030216; GO:0001889; GO:0006346; GO:0071565; GO:0060766; GO:0030308; GO:0000122; GO:0003407; GO:0071564; GO:0005719; GO:0006334; GO:0006337; GO:0005726; GO:0043923; GO:0043388; GO:0051091; GO:0045944; GO:0019827; GO:0003714; GO:0001570,ATP binding; ATPase activity; DNA methylation on cytosine within a CG sequence; DNA-dependent ATPase activity; RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II transcription coactivator activity; SWI/SNF complex; WINAC complex; aortic smooth muscle cell differentiation; blastocyst growth; blastocyst hatching; cell morphogenesis; chromatin binding; chromatin remodeling; definitive erythrocyte differentiation; embryonic hindlimb morphogenesis; embryonic organ morphogenesis; epidermis morphogenesis; extracellular matrix organization; forebrain development; glial cell fate determination; heart trabecula formation; helicase activity; heterochromatin; hindbrain development; histone H3 acetylation; keratinocyte differentiation; liver development; methylation-dependent chromatin silencing; nBAF complex; negative regulation of androgen receptor signaling pathway; negative regulation of cell growth; negative regulation of transcription from RNA polymerase II promoter; neural retina development; npBAF complex; nuclear euchromatin; nucleosome assembly; nucleosome disassembly; perichromatin fibrils; positive regulation by host of viral transcription; positive regulation of DNA binding; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance; transcription corepressor activity; vasculogenesis,PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;,2.00E-25,CHOYP_PB1.2.6,,,,,,,SMCA4_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; aortic smooth muscle cell differentiation [GO:0035887]; ATP-dependent chromatin remodeling [GO:0043044]; blastocyst growth [GO:0001832]; blastocyst hatching [GO:0001835]; blood vessel development [GO:0001568]; cell morphogenesis [GO:0000902]; chromatin remodeling [GO:0006338]; coronary vasculature development [GO:0060976]; definitive erythrocyte differentiation [GO:0060318]; DNA methylation on cytosine within a CG sequence [GO:0010424]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic organ morphogenesis [GO:0048562]; epidermis morphogenesis [GO:0048730]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; glial cell fate determination [GO:0007403]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; hindbrain development [GO:0030902]; histone H3 acetylation [GO:0043966]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; lens fiber cell development [GO:0070307]; liver development [GO:0001889]; methylation-dependent chromatin silencing [GO:0006346]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; outflow tract morphogenesis [GO:0003151]; pharyngeal arch artery morphogenesis [GO:0061626]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of cell migration [GO:0030334]; stem cell population maintenance [GO:0019827]; vasculogenesis [GO:0001570]; ventricular septum development [GO:0003281]" comp140235_c1_seq1,621,42.029,0.65766148,112,44,,8.00E-39,Q8BSQ9,Protein polybromo-1 (BRG1-associated factor 180) (BAF180),Protein polybromo-1 (BRG1-associated factor 180) (BAF180),GO:0003677; GO:0001974; GO:0060948; GO:0003682; GO:0016568; GO:0003349; GO:0003007; GO:0000776; GO:0008285; GO:0005634; GO:0001890; GO:0045893; GO:0006351; GO:0060979,"DNA binding; blood vessel remodeling; cardiac vascular smooth muscle cell development; chromatin binding; chromatin modification; epicardium-derived cardiac endothelial cell differentiation; heart morphogenesis; kinetochore; negative regulation of cell proliferation; nucleus; placenta development; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; vasculogenesis involved in coronary vascular morphogenesis",PF01426;PF00439;PF00505;,,,,,,,,,PB1_MOUSE,Mus musculus (Mouse),"blood vessel remodeling [GO:0001974]; cardiac vascular smooth muscle cell development [GO:0060948]; chromatin modification [GO:0016568]; epicardium-derived cardiac endothelial cell differentiation [GO:0003349]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; negative regulation of cell proliferation [GO:0008285]; placenta development [GO:0001890]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]" comp140237_c1_seq1,2174,44.8482,0.52624106,43,0,,1.00E-180,Q86VH2,Kinesin-like protein KIF27,Kinesin-like protein KIF27,GO:0005524; GO:0005929; GO:0042384; GO:0005737; GO:0003351; GO:0005871; GO:0005874; GO:0003777; GO:0021591,ATP binding; cilium; cilium assembly; cytoplasm; epithelial cilium movement; kinesin complex; microtubule; microtubule motor activity; ventricular system development,PF00225;,4.00E-171,CHOYP_LOC100373898.1.1,,,,,,,KIF27_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; microtubule-based movement [GO:0007018]; ventricular system development [GO:0021591] comp140237_c1_seq3,1656,45.1691,0.45287894,0,0,,1.00E-42,Q6S003,Kinesin-related protein 8 (Kinesin family member 8) (Kinesin-4),Kinesin-related protein 8 (Kinesin family member 8) (Kinesin-4),GO:0005524; GO:0051301; GO:0005737; GO:0031122; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007067; GO:0006810,ATP binding; cell division; cytoplasm; cytoplasmic microtubule organization; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; mitosis; transport,PF00225;PF00400;,,,,,,,,,KIF8_DICDI,Dictyostelium discoideum (Slime mold),cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; transport [GO:0006810] comp140237_c1_seq4,576,44.6181,0.45444218,3,0,,,,,,,,,4.00E-25,CHOYP_LOC100373898.1.1,,,,,,,,, comp140239_c0_seq2,1591,41.6091,0.51904037,51,149,,0,Q9DBL1,"Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)","Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)",GO:0003995; GO:0006631; GO:0050660; GO:0005759; GO:0005739,acyl-CoA dehydrogenase activity; fatty acid metabolic process; flavin adenine dinucleotide binding; mitochondrial matrix; mitochondrion,PF00441;PF02770;PF02771;,0,CHOYP_LOC100692418.1.1,,,,,,,ACDSB_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp140240_c0_seq4,1646,37.8493,1.24312357,34,0,,7.00E-13,A6NFU0,Ig-like V-type domain-containing protein FAM187A,Ig-like V-type domain-containing protein FAM187A,GO:0016021,integral to membrane,PF07686;,,,,,,,,,F187A_HUMAN,Homo sapiens (Human), comp140240_c0_seq6,1645,37.6292,1.2023761,2,0,,4.00E-13,A6NFU0,Ig-like V-type domain-containing protein FAM187A,Ig-like V-type domain-containing protein FAM187A,GO:0016021,integral to membrane,PF07686;,,,,,,,,,F187A_HUMAN,Homo sapiens (Human), comp140241_c0_seq1,1085,41.3825,0.49051532,128,1246,,2.00E-25,Q7T0Q5,Nucleolar protein 10,Nucleolar protein 10,GO:0005730,nucleolus,PF08159;,3.00E-35,CHOYP_NOL10.1.1,,,,,,,NOL10_XENLA,Xenopus laevis (African clawed frog), comp140244_c0_seq1,2480,39.7581,1.00360366,0,0,,0,Q06248,Heat shock 70 kDa protein IV (HSP70 IV),Heat shock 70 kDa protein IV (HSP70 IV),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,2.00E-143,CHOYP_BRAFLDRAFT_114843.1.2,,,,,,,HSP74_PARLI,Paracentrotus lividus (Common sea urchin), comp140244_c0_seq2,2468,39.8298,1.00499269,0,0,,0,Q91233,Heat shock 70 kDa protein (HSP70),Heat shock 70 kDa protein (HSP70),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,0,CHOYP_HSP7D.3.3,9.00E-32,ruditapes2_c147,,,,,HSP70_ONCTS,Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha), comp140244_c0_seq3,2429,40.634,1.02189257,0,0,,0,P41827,Heat shock protein 70 B2,Heat shock protein 70 B2,GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,0,CHOYP_HSP7D.2.3,,,,,,,HSP74_ANOAL,Anopheles albimanus (New world malaria mosquito), comp140244_c0_seq4,2441,40.5571,1.02056855,0,0,,0,Q91233,Heat shock 70 kDa protein (HSP70),Heat shock 70 kDa protein (HSP70),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,0,CHOYP_HSC70.1.1,,,,,,,HSP70_ONCTS,Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha), comp140246_c2_seq2,1883,41.795,0.48686587,98,320,,1.00E-46,Q9QXW0,F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6),F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6),,,PF12937;,,,,,,,,,FBXL6_MOUSE,Mus musculus (Mouse), comp140247_c3_seq1,1076,39.2193,0.29070813,0,4,,,,,,,,,1.00E-16,CHOYP_SMN2.1.2,,,,,,,,, comp140247_c3_seq2,1310,40.458,0.35842372,19,129,,1.00E-13,O18870,Survival motor neuron protein,Survival motor neuron protein,GO:0097504; GO:0003723; GO:0008380; GO:0007409; GO:0005737; GO:0006397; GO:0007019; GO:0005681,Gemini of coiled bodies; RNA binding; RNA splicing; axonogenesis; cytoplasm; mRNA processing; microtubule depolymerization; spliceosomal complex,PF06003;,,,,,,,,,SMN_BOVIN,Bos taurus (Bovine),"axonogenesis [GO:0007409]; DNA-templated transcription, termination [GO:0006353]; microtubule depolymerization [GO:0007019]; positive regulation of RNA splicing [GO:0033120]; regulation of neuron projection development [GO:0010975]; spliceosomal snRNP assembly [GO:0000387]" comp140248_c0_seq1,2871,41.1355,0.89825209,7138,252,,7.00E-104,Q9I9B9,Choline transporter-like protein 1 (Solute carrier family 44 member 1),Choline transporter-like protein 1 (Solute carrier family 44 member 1),GO:0016021; GO:0006810,integral to membrane; transport,PF04515;,3.00E-73,CHOYP_BRAFLDRAFT_127837.1.1,,,,,,,CTL1_TORMA,Torpedo marmorata (Marbled electric ray),transport [GO:0006810] comp140249_c0_seq1,1310,36.7939,0.36130654,515,1596,,1.00E-28,Q5XIM4,"ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (Mitochondrial ATP synthase regulatory component factor B)","ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (Mitochondrial ATP synthase regulatory component factor B)",GO:0006754; GO:0046872; GO:0005743; GO:0015992; GO:0045263,"ATP biosynthetic process; metal ion binding; mitochondrial inner membrane; proton transport; proton-transporting ATP synthase complex, coupling factor F(o)",,,,,,,,,,ATP5S_RAT,Rattus norvegicus (Rat),ATP biosynthetic process [GO:0006754]; proton transport [GO:0015992] comp140250_c0_seq1,933,40.5145,0.31848184,47,125,,1.00E-29,B1WAX6,"Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator)","Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator)",GO:0004331,"fructose-2,6-bisphosphate 2-phosphatase activity",PF00300;,,,,,,,,,TIGAR_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"apoptotic process [GO:0006915]; autophagy [GO:0006914]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 2,6-bisphosphate metabolic process [GO:0006003]" comp140251_c0_seq1,1244,35.9325,0.63655555,0,4,,2.00E-19,Q2S8Y5,Iron-sulfur cluster insertion protein ErpA,Iron-sulfur cluster insertion protein ErpA,GO:0005506; GO:0016226; GO:0051536; GO:0005198,iron ion binding; iron-sulfur cluster assembly; iron-sulfur cluster binding; structural molecule activity,PF01521;,8.00E-25,CHOYP_LOC724467.1.1,,,,,,,ERPA_HAHCH,Hahella chejuensis (strain KCTC 2396),iron-sulfur cluster assembly [GO:0016226] comp140251_c0_seq3,1362,36.7107,0.57586277,38,60,,5.00E-41,Q86U28,"Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1)","Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1)",GO:0016226; GO:0051536; GO:0046872; GO:0005739; GO:0005198,iron-sulfur cluster assembly; iron-sulfur cluster binding; metal ion binding; mitochondrion; structural molecule activity,PF01521;,9.00E-25,CHOYP_LOC724467.1.1,,,,,,,ISCA2_HUMAN,Homo sapiens (Human),iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; sulfur compound metabolic process [GO:0006790] comp140252_c0_seq3,2462,41.6328,0.41394965,0,0,,3.00E-25,Q03169,Tumor necrosis factor alpha-induced protein 2 (TNF alpha-induced protein 2) (Primary response gene B94 protein),Tumor necrosis factor alpha-induced protein 2 (TNF alpha-induced protein 2) (Primary response gene B94 protein),GO:0001525; GO:0030154; GO:0000145; GO:0006887; GO:0005615,angiogenesis; cell differentiation; exocyst; exocytosis; extracellular space,PF06046;,,,,,,,,,TNAP2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; exocyst localization [GO:0051601]; exocytosis [GO:0006887] comp140252_c0_seq4,2554,42.13,0.39882933,0,0,,0,Q62825,Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6),Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6),GO:0000145; GO:0006887; GO:0015031,exocyst; exocytosis; protein transport,PF06046;,4.00E-140,CHOYP_BRAFLDRAFT_119363.1.1,,,,,,,EXOC3_RAT,Rattus norvegicus (Rat),exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031] comp140252_c0_seq5,2566,42.1278,0.40605102,0,0,,0,Q62825,Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6),Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6),GO:0000145; GO:0006887; GO:0015031,exocyst; exocytosis; protein transport,PF06046;,4.00E-140,CHOYP_BRAFLDRAFT_119363.1.1,,,,,,,EXOC3_RAT,Rattus norvegicus (Rat),exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031] comp140252_c0_seq6,1272,44.9686,0.37454511,0,0,,2.00E-10,Q54BP6,Exocyst complex component 3 (Exocyst complex component Sec6),Exocyst complex component 3 (Exocyst complex component Sec6),GO:0000145; GO:0006887; GO:0015031,exocyst; exocytosis; protein transport,PF06046;,,,,,,,,,EXOC3_DICDI,Dictyostelium discoideum (Slime mold),exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031] comp140253_c0_seq1,2931,33.9133,0.40582972,354,2590,,,,,,,,,1.00E-65,CHOYP_RNF10.1.1,,,,,,,,, comp140253_c0_seq2,2956,34.0325,0.39953112,609,3008,,2.00E-56,Q5R4X4,Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha),Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF03896;,,,,,2.00E-64,AM854424.p.cg.6,3,,SSRA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140254_c0_seq1,3968,42.3135,0.52407323,12,29,,5.00E-66,Q9CSP9,Tetratricopeptide repeat protein 14 (TPR repeat protein 14),Tetratricopeptide repeat protein 14 (TPR repeat protein 14),GO:0003723,RNA binding,PF13414;,2.00E-45,CHOYP_TTC14.1.1,,,,,,,TTC14_MOUSE,Mus musculus (Mouse), comp140254_c0_seq6,1735,44.2651,0.56834586,0,0,,8.00E-69,Q9CSP9,Tetratricopeptide repeat protein 14 (TPR repeat protein 14),Tetratricopeptide repeat protein 14 (TPR repeat protein 14),GO:0003723,RNA binding,PF13414;,8.00E-46,CHOYP_TTC14.1.1,,,,,,,TTC14_MOUSE,Mus musculus (Mouse), comp140257_c1_seq2,2793,39.8138,0.56684368,0,0,,2.00E-10,Q8WZK0,U1 snRNP-associated protein usp107,U1 snRNP-associated protein usp107,GO:0003723; GO:0005685; GO:0005829; GO:0000395; GO:0000166; GO:0005681,RNA binding; U1 snRNP; cytosol; mRNA 5'-splice site recognition; nucleotide binding; spliceosomal complex,PF01480;PF00076;,1.00E-64,CHOYP_RBM25.1.2,,,,,,,YHRA_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp140257_c1_seq4,2808,39.8148,0.5728562,0,0,,7.00E-77,B2RY56,RNA-binding protein 25 (RNA-binding motif protein 25),RNA-binding protein 25 (RNA-binding motif protein 25),GO:0008380; GO:0005737; GO:0097194; GO:0003729; GO:0006397; GO:0016607; GO:0000166; GO:0000381,"RNA splicing; cytoplasm; execution phase of apoptosis; mRNA binding; mRNA processing; nuclear speck; nucleotide binding; regulation of alternative mRNA splicing, via spliceosome",PF01480;PF00076;,,,,,,,,,RBM25_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]" comp140257_c1_seq5,2625,42.0571,0.57394407,0,0,,2.00E-10,Q8WZK0,U1 snRNP-associated protein usp107,U1 snRNP-associated protein usp107,GO:0003723; GO:0005685; GO:0005829; GO:0000395; GO:0000166; GO:0005681,RNA binding; U1 snRNP; cytosol; mRNA 5'-splice site recognition; nucleotide binding; spliceosomal complex,PF01480;PF00076;,1.00E-64,CHOYP_RBM25.1.2,,,,,,,YHRA_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp140257_c1_seq6,2640,42.0455,0.57966741,0,0,,2.00E-77,P49756,RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7),RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7),GO:0008380; GO:0005737; GO:0097194; GO:0003729; GO:0006397; GO:0016607; GO:0000166; GO:0000381,"RNA splicing; cytoplasm; execution phase of apoptosis; mRNA binding; mRNA processing; nuclear speck; nucleotide binding; regulation of alternative mRNA splicing, via spliceosome",PF01480;PF00076;,,,,,,,,,RBM25_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]" comp140260_c1_seq2,656,37.9573,0.84883918,36,61,,2.00E-07,Q5UPX0,Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13),Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13),GO:0005524; GO:0043140; GO:0006310; GO:0006281; GO:0006260; GO:0003676,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA recombination; DNA repair; DNA replication; nucleic acid binding,PF00270;PF00271;PF16124;PF09382;,,,,,,,,,YR290_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp140262_c0_seq1,1127,37.7107,0.48270308,107,299,,1.00E-57,Q16667,Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase),Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase),GO:0000082; GO:0007050; GO:0008285; GO:0048471; GO:0004722; GO:0004725; GO:0008138; GO:0000079,G1/S transition of mitotic cell cycle; cell cycle arrest; negative regulation of cell proliferation; perinuclear region of cytoplasm; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of cyclin-dependent protein serine/threonine kinase activity,PF05706;,,,,,,,,,CDKN3_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] comp140262_c1_seq4,1362,36.7841,0.3802017,29,201,,3.00E-38,Q0VCW4,L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19),L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19),GO:0003941; GO:0006565; GO:0004794; GO:0005737; GO:0006094; GO:0042803; GO:0030170; GO:0042866,L-serine ammonia-lyase activity; L-serine catabolic process; L-threonine ammonia-lyase activity; cytoplasm; gluconeogenesis; protein homodimerization activity; pyridoxal phosphate binding; pyruvate biosynthetic process,PF00291;,,,,,,,,,SDHL_BOVIN,Bos taurus (Bovine),gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; pyruvate biosynthetic process [GO:0042866] comp140264_c2_seq1,1451,40.7994,0.76737169,0,0,,0,Q9UNH5,Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A),Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A),GO:0007049; GO:0051301; GO:0008283; GO:0005813; GO:0005737; GO:0005634; GO:0035335; GO:0004721; GO:0004725; GO:0008138; GO:0005819,cell cycle; cell division; cell proliferation; centrosome; cytoplasm; nucleus; peptidyl-tyrosine dephosphorylation; phosphoprotein phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; spindle,PF00782;PF14671;,0,CHOYP_CDC14A.1.1,,,,,,,CC14A_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cell proliferation [GO:0008283]; cilium assembly [GO:0042384]; mitotic cell cycle arrest [GO:0071850]; mitotic spindle midzone assembly [GO:0051256]; regulation of exit from mitosis [GO:0007096] comp140264_c2_seq3,1461,41.0678,0.76761732,0,0,,0,Q9UNH5,Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A),Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A),GO:0007049; GO:0051301; GO:0008283; GO:0005813; GO:0005737; GO:0005634; GO:0035335; GO:0004721; GO:0004725; GO:0008138; GO:0005819,cell cycle; cell division; cell proliferation; centrosome; cytoplasm; nucleus; peptidyl-tyrosine dephosphorylation; phosphoprotein phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; spindle,PF00782;PF14671;,0,CHOYP_CDC14A.1.1,,,,,,,CC14A_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cell proliferation [GO:0008283]; cilium assembly [GO:0042384]; mitotic cell cycle arrest [GO:0071850]; mitotic spindle midzone assembly [GO:0051256]; regulation of exit from mitosis [GO:0007096] comp140264_c2_seq4,727,44.9794,0.60607093,0,0,,3.00E-11,Q6NT99,Dual specificity protein phosphatase 23 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular mass dual specificity phosphatase 3) (LDP-3),Dual specificity protein phosphatase 23 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular mass dual specificity phosphatase 3) (LDP-3),GO:0005829; GO:0005634; GO:0035335; GO:0004725; GO:0008138,cytosol; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,,,4.00E-37,ruditapes_c26438,,,,,DUS23_MOUSE,Mus musculus (Mouse),dephosphorylation [GO:0016311] comp140265_c0_seq1,1792,40.067,0.97821627,531,2046,,9.00E-48,P78417,Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),GO:0019852; GO:0071243; GO:0005829; GO:0045174; GO:1901687; GO:0004364; GO:0050610; GO:0060315; GO:0060316; GO:0014810; GO:0010881; GO:0042178,L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; cytosol; glutathione dehydrogenase (ascorbate) activity; glutathione derivative biosynthetic process; glutathione transferase activity; methylarsonate reductase activity; negative regulation of ryanodine-sensitive calcium-release channel activity; positive regulation of ryanodine-sensitive calcium-release channel activity; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; xenobiotic catabolic process,PF14497;PF13417;,2.00E-14,CHOYP_BRAFLDRAFT_100190.1.1,8.00E-88,ruditapes_c10057,,,,,GSTO1_HUMAN,Homo sapiens (Human),cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178] comp140266_c2_seq1,1438,38.943,0.38722965,195,683,,3.00E-166,Q92643,GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K),GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K),GO:0006501; GO:0003923; GO:0042765; GO:0016255; GO:0004197; GO:0003756; GO:0006508,C-terminal protein lipidation; GPI-anchor transamidase activity; GPI-anchor transamidase complex; attachment of GPI anchor to protein; cysteine-type endopeptidase activity; protein disulfide isomerase activity; proteolysis,PF01650;,5.00E-174,CHOYP_PHUM_PHUM387860.1.1,,,,,,,GPI8_HUMAN,Homo sapiens (Human),attachment of GPI anchor to protein [GO:0016255]; protein localization to cell surface [GO:0034394] comp140269_c0_seq1,2077,42.6577,0.48798446,337,1541,,0,Q9JLJ2,4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3),4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3),GO:0047105; GO:0019145; GO:0045329; GO:0009437; GO:0006081; GO:0005829; GO:0005739; GO:0042136; GO:0016620,"4-trimethylammoniobutyraldehyde dehydrogenase activity; aminobutyraldehyde dehydrogenase activity; carnitine biosynthetic process; carnitine metabolic process; cellular aldehyde metabolic process; cytosol; mitochondrion; neurotransmitter biosynthetic process; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",PF00171;,1.00E-132,CHOYP_BRAFLDRAFT_127028.1.1,7.00E-58,ruditapes_c10986,,,,,AL9A1_MOUSE,Mus musculus (Mouse),carnitine biosynthetic process [GO:0045329]; carnitine metabolic process [GO:0009437]; cellular aldehyde metabolic process [GO:0006081]; neurotransmitter biosynthetic process [GO:0042136]; oxidation-reduction process [GO:0055114] comp140272_c0_seq1,2814,41.8266,0.47295855,2,16,,7.00E-130,Q5VYS8,Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6),Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6),GO:0031123; GO:0050265; GO:0003676; GO:0008270,RNA 3'-end processing; RNA uridylyltransferase activity; nucleic acid binding; zinc ion binding,PF01909;PF03828;PF00098;,1.00E-58,CHOYP_TUT4.2.2,,,,,,,TUT7_HUMAN,Homo sapiens (Human),RNA 3'-end processing [GO:0031123] comp140272_c0_seq3,2701,42.1325,0.45957929,27,0,,2.00E-130,Q5VYS8,Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6),Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6),GO:0031123; GO:0050265; GO:0003676; GO:0008270,RNA 3'-end processing; RNA uridylyltransferase activity; nucleic acid binding; zinc ion binding,PF01909;PF03828;PF00098;,2.00E-61,CHOYP_TUT4.2.2,,,,,,,TUT7_HUMAN,Homo sapiens (Human),RNA 3'-end processing [GO:0031123] comp140274_c0_seq1,1637,42.0281,0.34888192,203,1313,,6.00E-78,Q5XIJ1,Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein (ES cell-specific 5hmC-binding protein) (Putative peptidase SRAPD1) (EC 3.4.-.-) (SRAP domain-containing protein 1),Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein (ES cell-specific 5hmC-binding protein) (Putative peptidase SRAPD1) (EC 3.4.-.-) (SRAP domain-containing protein 1),,,PF02586;,3.00E-31,CHOYP_BRAFLDRAFT_278614.1.2,,,,,,,CC037_RAT,Rattus norvegicus (Rat), comp140276_c0_seq1,1685,42.908,0.4923386,0,0,,0,Q5FVA9,mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41),mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,0,CHOYP_RAEL1.1.1,,,,,,,RAE1L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] comp140276_c0_seq10,1192,45.5537,0.43776872,161,695,,5.00E-112,Q38942,Rae1-like protein At1g80670,Protein RAE1 (RNA export factor 1),GO:0080008; GO:0005829; GO:0005635,Cul4-RING ubiquitin ligase complex; cytosol; nuclear envelope,PF00400;,,,,,,,,,RAE1L_ARATH,Arabidopsis thaliana (Mouse-ear cress),mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] comp140276_c0_seq13,2269,38.387,0.49072551,56,165,,0,Q5FVA9,mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41),mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,,,8.00E-58,ruditapes_c5575,,,,,RAE1L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] comp140276_c0_seq2,2641,39.0761,0.52619205,0,0,,2.00E-39,O42860,Mitotic checkpoint protein bub3,Mitotic checkpoint protein bub3,GO:0051301; GO:0034613; GO:0000778; GO:0007067; GO:0033597; GO:0007094,cell division; cellular protein localization; condensed nuclear chromosome kinetochore; mitosis; mitotic checkpoint complex; mitotic spindle assembly checkpoint,PF00400;,,,,,,,,,BUB3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell division [GO:0051301]; cellular protein localization [GO:0034613]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; signal transduction involved in mitotic spindle assembly checkpoint [GO:0072480] comp140276_c0_seq3,1710,41.8713,0.49565874,0,65,,6.00E-07,Q0U1B1,Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog),Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog),GO:0051301; GO:0006928; GO:0005737; GO:0000132; GO:0005874; GO:0005875; GO:0007067; GO:0000922; GO:0006810,cell division; cellular component movement; cytoplasm; establishment of mitotic spindle orientation; microtubule; microtubule associated complex; mitosis; spindle pole; transport,PF00400;,0,CHOYP_RAEL1.1.1,,,,,,,LIS1_PHANO,Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; reproduction [GO:0000003]; vesicle transport along microtubule [GO:0047496] comp140276_c0_seq4,2660,39.0977,0.51185199,0,0,,5.00E-09,Q498M4,WD repeat-containing protein 5,WD repeat-containing protein 5,GO:0005671; GO:0071339; GO:0048188; GO:0043966; GO:0051568; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0042800; GO:0035064; GO:0006355; GO:0001501; GO:0006351,"Ada2/Gcn5/Ada3 transcription activator complex; MLL1 complex; Set1C/COMPASS complex; histone H3 acetylation; histone H3-K4 methylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; histone methyltransferase activity (H3-K4 specific); methylated histone residue binding; regulation of transcription, DNA-dependent; skeletal system development; transcription, DNA-dependent",PF00400;,,,,,,,,,WDR5_RAT,Rattus norvegicus (Rat),"histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]" comp140276_c0_seq5,2647,38.4586,0.54200064,0,0,,0,Q5FVA9,mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41),mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,,,,,,,,,RAE1L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] comp140276_c0_seq6,1704,43.0164,0.4838615,0,0,,2.00E-10,Q4V7Y7,Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),GO:0051301; GO:0008352; GO:0005874; GO:0051013; GO:0007067; GO:0000922,cell division; katanin complex; microtubule; microtubule severing; mitosis; spindle pole,PF13925;PF00400;,0,CHOYP_RAEL1.1.1,,,,,,,KTNB1_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067] comp140276_c0_seq7,1691,41.8687,0.51564285,0,0,,2.00E-60,Q9WVA3,Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5),Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5),GO:0008608; GO:0051301; GO:0000777; GO:0007126; GO:0000070; GO:0005634; GO:0051983; GO:0071173,attachment of spindle microtubules to kinetochore; cell division; condensed chromosome kinetochore; meiosis; mitotic sister chromatid segregation; nucleus; regulation of chromosome segregation; spindle assembly checkpoint,PF00400;,,,,,,,,,BUB3_MOUSE,Mus musculus (Mouse),attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of chromosome segregation [GO:0051983]; spindle assembly checkpoint [GO:0071173] comp140276_c0_seq9,2666,38.5596,0.5453245,142,499,,1.00E-06,Q0U1B1,Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog),Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog),GO:0051301; GO:0006928; GO:0005737; GO:0000132; GO:0005874; GO:0005875; GO:0007067; GO:0000922; GO:0006810,cell division; cellular component movement; cytoplasm; establishment of mitotic spindle orientation; microtubule; microtubule associated complex; mitosis; spindle pole; transport,PF00400;,,,,,,,,,LIS1_PHANO,Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; reproduction [GO:0000003]; vesicle transport along microtubule [GO:0047496] comp140277_c0_seq1,2044,40.4599,0.39469538,138,524,,2.00E-139,Q6GPJ5,Leucine-rich repeat-containing protein 40,Leucine-rich repeat-containing protein 40,,,PF13855;,1.00E-31,CHOYP_LRC40.1.2,4.00E-17,ruditapes_c24387,,,,,LRC40_XENLA,Xenopus laevis (African clawed frog), comp140278_c0_seq1,3083,38.4042,0.5455416,875,6331,,7.00E-33,Q9NRD1,F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2),F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2),GO:0000077; GO:0006281; GO:0030433; GO:0019005; GO:0031146; GO:0030246; GO:0005737; GO:0001948; GO:0006516; GO:0006986; GO:0004842,DNA damage checkpoint; DNA repair; ER-associated protein catabolic process; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; carbohydrate binding; cytoplasm; glycoprotein binding; glycoprotein catabolic process; response to unfolded protein; ubiquitin-protein ligase activity,PF12937;PF04300;,,,,,,,,,FBX6_HUMAN,Homo sapiens (Human),DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; response to unfolded protein [GO:0006986]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp140278_c1_seq1,551,35.2087,0.4693893,46,60,,3.00E-23,Q95XU6,Zinc finger CCCH domain-containing protein 14 (Suppressor of tau pathology protein 2),Zinc finger CCCH domain-containing protein 14 (Suppressor of tau pathology protein 2),GO:0046872; GO:0005634; GO:0048471,metal ion binding; nucleus; perinuclear region of cytoplasm,PF01480;,6.00E-29,CHOYP_LOC101155562.1.1,,,,,,,ZC3HE_CAEEL,Caenorhabditis elegans,mRNA processing [GO:0006397]; negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488] comp140278_c2_seq4,1704,41.9601,0.32035334,0,0,,6.00E-42,Q5F3Z9,Zinc finger CCCH domain-containing protein 14,Zinc finger CCCH domain-containing protein 14,GO:0003723; GO:0046872; GO:0016607; GO:0005634,RNA binding; metal ion binding; nuclear speck; nucleus,,,,,,,,,,ZC3HE_CHICK,Gallus gallus (Chicken),negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488] comp140278_c2_seq9,1115,45.8296,0.32572455,0,0,,2.00E-43,Q5F3Z9,Zinc finger CCCH domain-containing protein 14,Zinc finger CCCH domain-containing protein 14,GO:0003723; GO:0046872; GO:0016607; GO:0005634,RNA binding; metal ion binding; nuclear speck; nucleus,,2.00E-25,CHOYP_LOC101155562.1.1,,,,,,,ZC3HE_CHICK,Gallus gallus (Chicken),negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488] comp140279_c0_seq1,546,43.0403,0.54051565,12,5,,3.00E-11,Q5B3I8,mRNA 3'-end-processing protein rna14,mRNA 3'-end-processing protein rna14,GO:0005737; GO:0006397; GO:0005634,cytoplasm; mRNA processing; nucleus,PF05843;,9.00E-39,CHOYP_BRAFLDRAFT_117858.3.3,,,,,,,RNA14_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; response to DNA damage checkpoint signaling [GO:0072423]; RNA 3'-end processing [GO:0031123] comp140279_c0_seq2,1494,43.1058,0.40145023,89,209,,6.00E-124,Q86UA1,Pre-mRNA-processing factor 39 (PRP39 homolog),Pre-mRNA-processing factor 39 (PRP39 homolog),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,,,,,,,,,,PRP39_HUMAN,Homo sapiens (Human),mRNA 5'-splice site recognition [GO:0000395] comp140279_c0_seq3,561,42.6025,0.53807801,5,0,,1.00E-08,P39682,Pre-mRNA-processing factor 39,Pre-mRNA-processing factor 39,GO:0005685; GO:0071004; GO:0000243; GO:0000395,U1 snRNP; U2-type prespliceosome; commitment complex; mRNA 5'-splice site recognition,,,,,,,,,,PRP39_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),mRNA 5'-splice site recognition [GO:0000395] comp140281_c1_seq1,1597,40.2004,0.68798461,10,6,,,,,,,,,6.00E-47,CHOYP_LOC752904.1.1,,,,,,,,, comp140281_c1_seq2,1471,42.3521,0.70331164,36,68,,3.00E-53,Q5W5X9,Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8),Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8),,,,,,,,,,,,TTC23_HUMAN,Homo sapiens (Human), comp140285_c0_seq1,1605,36.1994,0.68207768,1640,12036,,4.00E-36,O35796,"Complement component 1 Q subcomponent-binding protein, mitochondrial (GC1q-R protein) (Glycoprotein gC1qBP) (C1qBP)","Complement component 1 Q subcomponent-binding protein, mitochondrial (GC1q-R protein) (Glycoprotein gC1qBP) (C1qBP)",GO:0008380; GO:0031690; GO:0006915; GO:0009986; GO:0006958; GO:0001849; GO:0005737; GO:0005829; GO:0005615; GO:0005540; GO:0006955; GO:0045087; GO:0030984; GO:0003729; GO:0006397; GO:0042256; GO:0005759; GO:0097177; GO:0039534; GO:0039536; GO:0050687; GO:0032689; GO:0032695; GO:0048025; GO:0000122; GO:0005730; GO:0005634; GO:0014065; GO:0005886; GO:0043065; GO:2000510; GO:0070131; GO:0090023; GO:0051897; GO:1900026; GO:1901165; GO:0005080; GO:0030449; GO:0003714; GO:0006351,"RNA splicing; adrenergic receptor binding; apoptotic process; cell surface; complement activation, classical pathway; complement component C1q binding; cytoplasm; cytosol; extracellular space; hyaluronic acid binding; immune response; innate immune response; kininogen binding; mRNA binding; mRNA processing; mature ribosome assembly; mitochondrial matrix; mitochondrial ribosome binding; negative regulation of MDA-5 signaling pathway; negative regulation of RIG-I signaling pathway; negative regulation of defense response to virus; negative regulation of interferon-gamma production; negative regulation of interleukin-12 production; negative regulation of mRNA splicing, via spliceosome; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; phosphatidylinositol 3-kinase cascade; plasma membrane; positive regulation of apoptotic process; positive regulation of dendritic cell chemotaxis; positive regulation of mitochondrial translation; positive regulation of neutrophil chemotaxis; positive regulation of protein kinase B signaling cascade; positive regulation of substrate adhesion-dependent cell spreading; positive regulation of trophoblast cell migration; protein kinase C binding; regulation of complement activation; transcription corepressor activity; transcription, DNA-dependent",PF02330;,,,,,,,,,C1QBP_RAT,Rattus norvegicus (Rat),"apoptotic process [GO:0006915]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; mature ribosome assembly [GO:0042256]; mRNA processing [GO:0006397]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of mitochondrial translation [GO:0070131]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of trophoblast cell migration [GO:1901165]; regulation of complement activation [GO:0030449]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp140288_c0_seq3,2132,35.6473,0.41162605,38,65,,2.00E-71,Q8BP78,Protein FRA10AC1 homolog,Protein FRA10AC1 homolog,GO:0005634,nucleus,PF09725;,2.00E-60,CHOYP_LOC100369464.1.1,,,,,,,F10C1_MOUSE,Mus musculus (Mouse), comp140291_c0_seq2,969,36.5325,0.49730891,0,0,,2.00E-12,P0CAT7,Alpha-ketoglutarate-dependent dioxygenase AlkB homolog (EC 1.14.11.33) (DNA oxidative demethylase AlkB),Alpha-ketoglutarate-dependent dioxygenase AlkB homolog (EC 1.14.11.33) (DNA oxidative demethylase AlkB),GO:0006281; GO:0046872; GO:0016706,"DNA repair; metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13532;,,,,,,,,,ALKB_CAUCR,Caulobacter crescentus (strain ATCC 19089 / CB15),DNA repair [GO:0006281] comp140291_c0_seq3,1431,37.9455,0.48726069,0,7,,6.00E-68,Q13686,Alkylated DNA repair protein alkB homolog 1 (EC 1.14.11.33) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA lyase ABH1) (EC 4.2.99.18) (DNA oxidative demethylase ALKBH1),DNA demethylase ALKBH1 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 1) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA 6mA demethylase) (DNA N6-methyl adenine demethylase) (EC 1.14.11.-) (DNA lyase ABH1) (EC 4.2.99.18) (DNA oxidative demethylase ALKBH1) (EC 1.14.11.33),GO:0006307; GO:0080111; GO:0003906; GO:0042245; GO:0042056; GO:0048589; GO:0008198; GO:0001701; GO:0070579; GO:0005739; GO:0043524; GO:0001764; GO:0031175; GO:0005719; GO:0070989; GO:0001890,DNA dealkylation involved in DNA repair; DNA demethylation; DNA-(apurinic or apyrimidinic site) lyase activity; RNA repair; chemoattractant activity; developmental growth; ferrous iron binding; in utero embryonic development; methylcytosine dioxygenase activity; mitochondrion; negative regulation of neuron apoptotic process; neuron migration; neuron projection development; nuclear euchromatin; oxidative demethylation; placenta development,PF13532;,,,,,,,,,ALKB1_HUMAN,Homo sapiens (Human),developmental growth [GO:0048589]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; in utero embryonic development [GO:0001701]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; oxidative demethylation [GO:0070989]; placenta development [GO:0001890]; regulation of gene expression [GO:0010468]; RNA repair [GO:0042245] comp140293_c0_seq1,3219,40.4784,0.66763746,0,0,,2.00E-37,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140293_c0_seq6,1395,40.4301,0.98306201,0,0,,2.00E-08,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140294_c0_seq3,1128,41.844,0.42661302,0,0,,9.00E-81,Q9P275,Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36),Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36),GO:0008234; GO:0005730; GO:0004221; GO:0006511,cysteine-type peptidase activity; nucleolus; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,2.00E-20,CHOYP_USP36.2.2,,,,,,,UBP36_HUMAN,Homo sapiens (Human),positive regulation of protein targeting to mitochondrion [GO:1903955]; protein deubiquitination [GO:0016579]; regulation of mitophagy [GO:1903146]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140294_c0_seq4,865,41.0405,0.22066535,0,0,,1.00E-22,Q9Y6I4,Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3),Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3),GO:0006281; GO:0016578; GO:0000278; GO:0000790; GO:0031647; GO:0004221; GO:0006511; GO:0004843; GO:0008270,DNA repair; histone deubiquitination; mitotic cell cycle; nuclear chromatin; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding,PF00443;PF02148;,,,,,,,,,UBP3_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140294_c0_seq7,1529,42.3152,0.33632173,0,0,,2.00E-101,D3ZU96,Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42),Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42),GO:0030154; GO:0016579; GO:0007283; GO:0004221; GO:0006511; GO:0004843,cell differentiation; protein deubiquitination; spermatogenesis; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,2.00E-20,CHOYP_USP36.2.2,,,,,,,UBP42_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; protein deubiquitination [GO:0016579]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140295_c1_seq2,5491,32.4167,0.34377866,2321,4651,,,,,,,,,,,2.00E-19,ruditapes_c2972,,,,,,, comp140297_c0_seq1,2435,32.4435,0.50453071,300,328,,6.00E-93,P63100,Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1),Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1),GO:0005509; GO:0005829; GO:0004721; GO:0006470,calcium ion binding; cytosol; phosphoprotein phosphatase activity; protein dephosphorylation,PF13499;,1.00E-114,CHOYP_EF1G.1.3,1.00E-99,ruditapes_c19432,,,,,CANB1_RAT,Rattus norvegicus (Rat),protein dephosphorylation [GO:0006470] comp140300_c1_seq1,1437,37.8566,1.04963554,0,11,,,,,,,,,,,5.00E-13,ruditapes_c11289,,,,,,, comp140300_c1_seq2,2892,43.2573,0.95452185,21,1143,,2.00E-173,Q9Y345,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015375; GO:0016021; GO:0005328; GO:0005886; GO:0007268,glycine:sodium symporter activity; integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane; synaptic transmission,PF00209;,4.00E-96,CHOYP_AT1.1.1,,,,,,,SC6A5_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp140301_c0_seq1,1288,37.4224,0.47154457,0,0,,1.00E-06,Q9QC07,HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K(C1a) Pol protein) (HERV-K110 Pol protein) (HERV-K18 Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (RNase H) (EC 3.1.26.4)],Endogenous retrovirus group K member 18 Pol protein (HERV-K(C1a) Pol protein) (HERV-K110 Pol protein) (HERV-K18 Pol protein) (HERV-K_1q23.3 provirus ancestral Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (RNase H) (EC 3.1.26.4)],GO:0003677; GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0090305; GO:0004523; GO:0008270,DNA binding; DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; zinc ion binding,PF02022;PF00075;PF00665;PF00078;PF06817;,,,,,,,,,POK7_HUMAN,Homo sapiens (Human),DNA integration [GO:0015074] comp140301_c0_seq2,1770,38.2486,0.48446919,49,62,,6.00E-31,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp140301_c0_seq3,313,37.0607,0.18757659,20,6,,8.00E-15,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp140302_c0_seq1,1407,40.9382,0.84218793,173,481,,1.00E-53,Q95JD5,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-),GO:0004062; GO:0005737; GO:0009812; GO:0008202; GO:0051923; GO:0042403; GO:0006805,aryl sulfotransferase activity; cytoplasm; flavonoid metabolic process; steroid metabolic process; sulfation; thyroid hormone metabolic process; xenobiotic metabolic process,PF00685;,2.00E-15,CHOYP_LOC100717261.1.1,2.00E-12,ruditapes_c11831,,,,,ST1B1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp140305_c0_seq1,1349,42.7724,0.86246431,28,173,,6.00E-43,Q9WY68,Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7),Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7),GO:0008660; GO:0008152,1-aminocyclopropane-1-carboxylate deaminase activity; metabolic process,PF00291;,,,1.00E-20,ruditapes_c8621,,,,,1A1D_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099), comp140305_c0_seq2,1202,43.178,0.84490495,9,52,,1.00E-38,O57809,Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7),Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7),GO:0008660; GO:0008152,1-aminocyclopropane-1-carboxylate deaminase activity; metabolic process,PF00291;,,,,,,,,,1A1D_PYRHO,Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3), comp140308_c1_seq2,2968,44.2385,0.63620637,23,14,,0,P35251,Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit),Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit),GO:0005524; GO:0003689; GO:0005663; GO:0006271; GO:0008047; GO:0000278; GO:0005654; GO:0006297; GO:0006355; GO:0000722; GO:0032201; GO:0007004; GO:0006351; GO:0006283,"ATP binding; DNA clamp loader activity; DNA replication factor C complex; DNA strand elongation involved in DNA replication; enzyme activator activity; mitotic cell cycle; nucleoplasm; nucleotide-excision repair, DNA gap filling; regulation of transcription, DNA-dependent; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; telomere maintenance via telomerase; transcription, DNA-dependent; transcription-coupled nucleotide-excision repair",PF00004;PF00533;PF08519;,,,,,,,,,RFC1_HUMAN,Homo sapiens (Human),"DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; regulation of transcription, DNA-templated [GO:0006355]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp140308_c1_seq3,2915,44.4254,0.64310962,6,0,,0,P35601,Replication factor C subunit 1 (A1-P145) (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (Differentiation-specific element-binding protein) (ISRE-binding protein) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit),Replication factor C subunit 1 (A1-P145) (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (Differentiation-specific element-binding protein) (ISRE-binding protein) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit),GO:0005524; GO:0003689; GO:0006260; GO:0005663; GO:0005634; GO:0006355; GO:0006351,"ATP binding; DNA clamp loader activity; DNA replication; DNA replication factor C complex; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00004;PF00533;PF08519;,1.00E-179,CHOYP_RFC1.1.3,,,,,,,RFC1_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140311_c0_seq2,1007,40.4171,0.61206706,99,446,,3.00E-79,Q9D273,"Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B homolog)","Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B homolog)",GO:0005524; GO:0008817; GO:0009236; GO:0005739,"ATP binding; cob(I)yrinic acid a,c-diamide adenosyltransferase activity; cobalamin biosynthetic process; mitochondrion",PF01923;,2.00E-19,CHOYP_MMAB.1.1,,,,,,,MMAB_MOUSE,Mus musculus (Mouse),cobalamin biosynthetic process [GO:0009236]; cobalamin metabolic process [GO:0009235] comp140314_c6_seq1,2164,40.1109,0.49248528,694,3782,,0,Q9BZE4,Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB),Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB),GO:0005525; GO:0003924; GO:0005794; GO:0008156; GO:0030336; GO:0008285; GO:0022408; GO:0033342; GO:0031397; GO:0031965; GO:0005730; GO:0048471; GO:0050821; GO:0000079; GO:0042254,GTP binding; GTPase activity; Golgi apparatus; negative regulation of DNA replication; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of cell-cell adhesion; negative regulation of collagen binding; negative regulation of protein ubiquitination; nuclear membrane; nucleolus; perinuclear region of cytoplasm; protein stabilization; regulation of cyclin-dependent protein serine/threonine kinase activity; ribosome biogenesis,PF06858;PF08155;,0,CHOYP_LOC100370136.1.1,,,,,,,NOG1_HUMAN,Homo sapiens (Human),negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of collagen binding [GO:0033342]; negative regulation of DNA replication [GO:0008156]; negative regulation of protein ubiquitination [GO:0031397]; osteoblast differentiation [GO:0001649]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; ribosome biogenesis [GO:0042254] comp140314_c8_seq1,824,45.6311,0.8472413,49776,196072,,2.00E-78,P84100,60S ribosomal protein L19,60S ribosomal protein L19,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01280;,3.00E-110,CHOYP_LOC100114310.2.2,3.00E-178,ruditapes2_c361,,,,,RL19_RAT,Rattus norvegicus (Rat),liver regeneration [GO:0097421]; translation [GO:0006412] comp140315_c0_seq1,1350,41.7037,0.58319201,449,2164,,4.00E-118,Q67ER4,RING finger protein 113A (Zinc finger protein 183),RING finger protein 113A (Zinc finger protein 183),GO:0008270,zinc ion binding,PF00642;,7.00E-96,CHOYP_LOC100136190.1.1,,,,,,,R113A_BOVIN,Bos taurus (Bovine),"mRNA cis splicing, via spliceosome [GO:0045292]; snoRNA splicing [GO:0034247]" comp140317_c0_seq1,1055,40.5687,0.44159828,84,475,,1.00E-96,Q6NU91,Nucleolar complex protein 4 homolog B (NOC4 protein homolog B) (NOC4-like protein B) (Nucleolar complex-associated protein 4-like protein B),Nucleolar complex protein 4 homolog B (NOC4 protein homolog B) (NOC4-like protein B) (Nucleolar complex-associated protein 4-like protein B),GO:0016021; GO:0031965; GO:0005730; GO:0042254,integral to membrane; nuclear membrane; nucleolus; ribosome biogenesis,PF03914;,,,,,,,,,NOC4B_XENLA,Xenopus laevis (African clawed frog),ribosome biogenesis [GO:0042254] comp140317_c0_seq2,964,40.9751,0.39896684,53,420,,,,,,,,,3.00E-29,CHOYP_NOC41.1.1,,,,,,,,, comp140317_c1_seq1,562,42.7046,0.31286568,290,931,,2.00E-20,P41843,Uncharacterized protein T20B12.3,Uncharacterized protein T20B12.3,GO:0042254,ribosome biogenesis,PF03914;,,,,,,,,,YO93_CAEEL,Caenorhabditis elegans,"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp140319_c0_seq1,2074,39.3925,0.46083444,151,612,,2.00E-86,O95159,Zinc finger protein-like 1 (Zinc finger protein MCG4),Zinc finger protein-like 1 (Zinc finger protein MCG4),GO:0003677; GO:0005794; GO:0016021; GO:0005634; GO:0006355; GO:0016192; GO:0008270,"DNA binding; Golgi apparatus; integral to membrane; nucleus; regulation of transcription, DNA-dependent; vesicle-mediated transport; zinc ion binding",,7.00E-54,CHOYP_BRAFLDRAFT_114510.1.1,,,,,,,ZFPL1_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; vesicle-mediated transport [GO:0016192]" comp14031_c0_seq1,201,30.8458,0.63060874,7,2,,6.00E-17,Q9H4Q4,PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),GO:0003677; GO:0046872; GO:0008168; GO:0022008; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; neurogenesis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD12_HUMAN,Homo sapiens (Human),"neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140322_c0_seq1,1617,35.8071,0.33264815,65,784,,8.00E-38,Q6NW29,RWD domain-containing protein 4 (Protein FAM28A),RWD domain-containing protein 4 (Protein FAM28A),,,PF05773;,3.00E-32,CHOYP_DPSE_GA10259.1.1,,,,,,,RWDD4_HUMAN,Homo sapiens (Human), comp140325_c0_seq1,1701,37.2134,0.27185794,538,921,,,,,,,,,,,6.00E-13,ruditapes_c29520,,,,,,, comp140327_c0_seq1,927,38.4035,1.08713399,142,942,,1.00E-10,Q8CG65,SCO-spondin,SCO-spondin,GO:0007155; GO:0005737; GO:0005615,cell adhesion; cytoplasm; extracellular space,PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;,,,,,,,,,SSPO_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp140328_c0_seq1,2588,39.915,0.45074197,342,2770,,5.00E-57,Q9BVJ6,U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16),U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16),GO:0005730; GO:0006364; GO:0032040,nucleolus; rRNA processing; small-subunit processome,PF04615;,1.00E-27,CHOYP_UT14A.1.1,,,,,,,UT14A_HUMAN,Homo sapiens (Human),maturation of SSU-rRNA [GO:0030490]; rRNA processing [GO:0006364] comp140330_c1_seq1,1476,37.9404,0.9501574,51,59,,4.00E-22,Q8R0M8,Monocarboxylate transporter 5 (MCT 5),Monocarboxylate transporter 5 (MCT 5),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT5_MOUSE,Mus musculus (Mouse),plasma membrane lactate transport [GO:0035879] comp140330_c1_seq2,1447,39.8065,1.06408046,6,50,,5.00E-35,O15374,Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,,,8.00E-11,ruditapes_c26172,,,,,MOT5_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp140330_c1_seq3,1959,38.5401,0.75179017,114,265,,8.00E-24,O15374,Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT5_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp140331_c0_seq1,216,42.5926,0.62268193,3,0,,1.00E-06,Q62234,Myomesin-1 (Myomesin family member 1) (Skelemin),Myomesin-1 (Myomesin family member 1) (Skelemin),GO:0031430; GO:0005856; GO:0006936; GO:0032982; GO:0042803; GO:0005200,M band; cytoskeleton; muscle contraction; myosin filament; protein homodimerization activity; structural constituent of cytoskeleton,PF00041;PF07679;,,,,,,,,,MYOM1_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp140331_c1_seq1,776,44.4588,0.6024078,38,5,,6.00E-21,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,,,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp140331_c1_seq10,724,46.2707,0.72370905,0,0,,8.00E-15,Q6PDN3,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687; GO:0014820,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity; tonic smooth muscle contraction,PF00041;PF07679;PF00069;,,,,,,,,,MYLK_MOUSE,Mus musculus (Mouse),aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to potassium ion [GO:0035865]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792] comp140331_c1_seq11,744,45.2957,0.68324638,0,0,,2.00E-13,P97527,Contactin-5 (Neural recognition molecule NB-2),Contactin-5 (Neural recognition molecule NB-2),GO:0031225; GO:0007155; GO:0005737; GO:0005886; GO:0007605,anchored to membrane; cell adhesion; cytoplasm; plasma membrane; sensory perception of sound,PF00041;PF07679;,,,,,,,,,CNTN5_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605] comp140331_c1_seq12,703,45.6615,0.68328425,0,0,,3.00E-17,P11799,"Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin)","Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0005829; GO:0016020; GO:0046872; GO:0004687,ATP binding; cytosol; membrane; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,4.00E-19,CHOYP_PHUM_PHUM226120.7.7,,,,,,,MYLK_CHICK,Gallus gallus (Chicken),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp140331_c1_seq13,683,46.7057,0.72680203,0,0,,2.00E-31,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp140331_c1_seq3,887,43.9684,0.4252879,176,144,,2.00E-13,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp140331_c1_seq5,653,46.4012,0.68601559,97,61,,4.00E-20,Q18066,Disorganized muscle protein 1 (2D-page protein spot 8),Disorganized muscle protein 1 (2D-page protein spot 8),GO:0005737,cytoplasm,PF07679;,,,3.00E-44,ruditapes_c11868,,,,,DIM_CAEEL,Caenorhabditis elegans, comp140331_c1_seq8,412,44.6602,0.5370008,3,0,,2.00E-07,Q0ZGT2,Nexilin (F-actin-binding protein) (Nelin),Nexilin (F-actin-binding protein) (Nelin),GO:0030018; GO:0051015; GO:0005924; GO:0005856; GO:0030334; GO:0051493; GO:0008307,Z disc; actin filament binding; cell-substrate adherens junction; cytoskeleton; regulation of cell migration; regulation of cytoskeleton organization; structural constituent of muscle,PF07679;,,,,,,,,,NEXN_HUMAN,Homo sapiens (Human),cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] comp140331_c1_seq9,347,46.6859,0.69333909,0,0,,6.00E-07,Q6PGX3,Leucine-rich repeat and fibronectin type III domain-containing protein 1,Leucine-rich repeat and fibronectin type III domain-containing protein 1,GO:0030054; GO:0016021; GO:0045202,cell junction; integral to membrane; synapse,PF13855;,,,,,,,,,LRFN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axonogenesis [GO:0007409] comp140333_c0_seq2,1693,34.6722,0.34217355,0,24,,6.00E-38,Q5XJ97,Nuclear nucleic acid-binding protein C1D,Nuclear nucleic acid-binding protein C1D,GO:0003677; GO:0003723; GO:0005737; GO:0005730; GO:0006364,DNA binding; RNA binding; cytoplasm; nucleolus; rRNA processing,PF04000;,6.00E-35,CHOYP_C1D.1.1,1.00E-65,ruditapes2_c928,,,,,C1D_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),rRNA processing [GO:0006364] comp140334_c0_seq2,1426,46.4937,0.45451672,0,0,,2.00E-50,A2AN08,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),GO:0005737; GO:0005856; GO:0016021; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp140334_c0_seq3,2353,46.3663,0.4509155,17,12,,,,,,,,,1.00E-25,CHOYP_UBR4.1.1,,,,,,,,, comp140334_c1_seq1,4533,47.1652,0.37300806,0,0,,0,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,0,CHOYP_UBR4.1.1,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp140334_c1_seq10,3771,46.725,0.39374459,0,0,,0,Q29L39,Protein purity of essence,Protein purity of essence,GO:0005516; GO:0007399; GO:0016567; GO:0050896; GO:0007291; GO:0004842; GO:0007601; GO:0008270,calmodulin binding; nervous system development; protein ubiquitination; response to stimulus; sperm individualization; ubiquitin-protein ligase activity; visual perception; zinc ion binding,PF13764;PF02207;,,,,,,,,,POE_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),nervous system development [GO:0007399]; response to stimulus [GO:0050896]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]; visual perception [GO:0007601] comp140334_c1_seq13,5961,47.9953,0.39915459,0,0,,0,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,0,CHOYP_UBR4.1.1,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp140334_c1_seq15,245,40,0.30943912,0,0,,6.00E-18,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp140334_c1_seq2,4600,47,0.37407146,0,0,,,,,,,,,0,CHOYP_UBR4.1.1,,,,,,,,, comp140334_c1_seq3,5917,48.0142,0.4018141,0,0,,0,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp140334_c1_seq5,5155,47.8177,0.4208941,0,0,,0,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,0,CHOYP_UBR4.1.1,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp140334_c1_seq7,2135,46.6979,0.38684448,0,0,,4.00E-107,B9G2A8,Auxin transport protein BIG,Auxin transport protein BIG,GO:0009734; GO:0009926; GO:0016021; GO:0007275; GO:0016567; GO:0004842; GO:0009826; GO:0008270,auxin mediated signaling pathway; auxin polar transport; integral to membrane; multicellular organismal development; protein ubiquitination; ubiquitin-protein ligase activity; unidimensional cell growth; zinc ion binding,PF13764;PF00569;,,,,,,,,,BIG_ORYSJ,Oryza sativa subsp. japonica (Rice),auxin-activated signaling pathway [GO:0009734]; auxin polar transport [GO:0009926]; multicellular organism development [GO:0007275]; unidimensional cell growth [GO:0009826] comp140334_c1_seq9,5199,47.7977,0.41767232,0,0,,0,Q5T4S7,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0019048; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032] comp140335_c2_seq1,269,27.1375,1.86638524,0,8,,,,,,,,,,,1.00E-19,ruditapes_lrc23864,,,,,,, comp140336_c1_seq1,1365,35.1648,0.55470642,134,489,,4.00E-106,A5PKG7,BTB/POZ domain-containing protein KCTD5,BTB/POZ domain-containing protein KCTD5,GO:0005829; GO:0051260,cytosol; protein homooligomerization,PF02214;,7.00E-115,CHOYP_LOC100068494.1.1,,,5.00E-113,AM867657.p.cg.6,3,female gonad,KCTD5_BOVIN,Bos taurus (Bovine),protein homooligomerization [GO:0051260] comp140337_c2_seq1,860,44.5349,0.69128,151,331,,2.00E-161,Q5ZMP6,AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein),AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein),GO:0030131; GO:0005905; GO:0006886; GO:0008289; GO:0005739; GO:0005886; GO:0016192,clathrin adaptor complex; coated pit; intracellular protein transport; lipid binding; mitochondrion; plasma membrane; vesicle-mediated transport,PF00928;PF01217;,8.00E-156,CHOYP_AP2M1.1.1,,,,,,,AP2M1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; negative regulation of protein localization to plasma membrane [GO:1903077] comp140337_c2_seq2,1127,36.646,0.62290565,222,662,,2.00E-32,Q99186,AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein),AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein),GO:0030122; GO:0006886; GO:0016192,AP-2 adaptor complex; intracellular protein transport; vesicle-mediated transport,PF00928;,,,,,,,,,AP2M_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] comp140338_c1_seq1,1879,36.083,0.39360748,315,517,,4.00E-174,O95363,"Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS)","Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS)",GO:0005524; GO:0000287; GO:0005759; GO:0004826; GO:0006432; GO:0000049; GO:0008033,ATP binding; magnesium ion binding; mitochondrial matrix; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding; tRNA processing,PF03147;PF01409;,2.00E-59,CHOYP_SYFM.1.1,,,,,,,SYFM_HUMAN,Homo sapiens (Human),phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033] comp140339_c0_seq1,1347,44.0238,0.46332932,154,544,,2.00E-117,Q6NYL3,"Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]","Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]",GO:0003857; GO:0050662; GO:0004165; GO:0004300; GO:0006635; GO:0005777,3-hydroxyacyl-CoA dehydrogenase activity; coenzyme binding; dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; fatty acid beta-oxidation; peroxisome,PF00725;PF02737;PF00378;,3.00E-44,CHOYP_EHHADH.1.1,,,,,,,ECHP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid beta-oxidation [GO:0006635] comp140340_c0_seq2,1448,33.011,0.6849268,33,118,,5.00E-28,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,2.00E-26,CHOYP_LOC100892567.5.8,1.00E-20,ruditapes_c9179,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp140343_c0_seq1,1405,41.7082,0.73823035,6,5,,0,Q9U2Q9,Glycogen synthase kinase-3 (EC 2.7.11.26),Glycogen synthase kinase-3 (EC 2.7.11.26),GO:0005524; GO:0060069; GO:0005737; GO:0043652; GO:0007281; GO:0007275; GO:0030178; GO:0004674; GO:0006950; GO:0050321,"ATP binding; Wnt receptor signaling pathway, regulating spindle positioning; cytoplasm; engulfment of apoptotic cell; germ cell development; multicellular organismal development; negative regulation of Wnt receptor signaling pathway; protein serine/threonine kinase activity; response to stress; tau-protein kinase activity",PF00069;,,,,,,,,,GSK3_CAEEL,Caenorhabditis elegans,"engulfment of apoptotic cell [GO:0043652]; germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; Wnt signaling pathway, regulating spindle positioning [GO:0060069]" comp140343_c0_seq2,2693,38.0988,0.66966753,278,376,,0,P49841,Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1),Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1),GO:0005524; GO:0006983; GO:0038095; GO:0007411; GO:0030877; GO:0060070; GO:0044337; GO:0016477; GO:0036016; GO:0005813; GO:0007623; GO:0005829; GO:0043198; GO:0043197; GO:0007173; GO:0001837; GO:0030010; GO:0097192; GO:0045444; GO:0008543; GO:0005977; GO:0030426; GO:0021766; GO:0044027; GO:0045087; GO:0045121; GO:0007520; GO:0043407; GO:0051534; GO:0043066; GO:0090090; GO:0050774; GO:2000466; GO:0045719; GO:0032091; GO:0031333; GO:0045892; GO:2000077; GO:0043025; GO:0048011; GO:0005634; GO:0009887; GO:0002039; GO:0018105; GO:0048471; GO:0048015; GO:0005886; GO:0032855; GO:0001954; GO:1901030; GO:0033138; GO:0010800; GO:0032092; GO:0045732; GO:0031334; GO:0046827; GO:2000738; GO:0045944; GO:0006611; GO:0035372; GO:0004674; GO:0000320; GO:0006349; GO:0032886; GO:0048168; GO:0042493; GO:0010226; GO:0030529; GO:0071109; GO:0050321,"ATP binding; ER overload response; Fc-epsilon receptor signaling pathway; axon guidance; beta-catenin destruction complex; canonical Wnt receptor signaling pathway; canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; cell migration; cellular response to interleukin-3; centrosome; circadian rhythm; cytosol; dendritic shaft; dendritic spine; epidermal growth factor receptor signaling pathway; epithelial to mesenchymal transition; establishment of cell polarity; extrinsic apoptotic signaling pathway in absence of ligand; fat cell differentiation; fibroblast growth factor receptor signaling pathway; glycogen metabolic process; growth cone; hippocampus development; hypermethylation of CpG island; innate immune response; membrane raft; myoblast fusion; negative regulation of MAP kinase activity; negative regulation of NFAT protein import into nucleus; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of dendrite morphogenesis; negative regulation of glycogen (starch) synthase activity; negative regulation of glycogen biosynthetic process; negative regulation of protein binding; negative regulation of protein complex assembly; negative regulation of transcription, DNA-dependent; negative regulation of type B pancreatic cell development; neuronal cell body; neurotrophin TRK receptor signaling pathway; nucleus; organ morphogenesis; p53 binding; peptidyl-serine phosphorylation; perinuclear region of cytoplasm; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of Rac GTPase activity; positive regulation of cell-matrix adhesion; positive regulation of mitochondrial outer membrane permeabilization; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein binding; positive regulation of protein catabolic process; positive regulation of protein complex assembly; positive regulation of protein export from nucleus; positive regulation of stem cell differentiation; positive regulation of transcription from RNA polymerase II promoter; protein export from nucleus; protein localization to microtubule; protein serine/threonine kinase activity; re-entry into mitotic cell cycle; regulation of gene expression by genetic imprinting; regulation of microtubule-based process; regulation of neuronal synaptic plasticity; response to drug; response to lithium ion; ribonucleoprotein complex; superior temporal gyrus development; tau-protein kinase activity",PF00069;,0,CHOYP_GSK3B.1.1,,,,,,,GSK3B_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; axonogenesis [GO:0007409]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of apoptotic process [GO:0044337]; cell migration [GO:0016477]; cellular response to dopamine [GO:1903351]; cellular response to erythropoietin [GO:0036018]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-3 [GO:0036016]; cellular response to iron(II) ion [GO:0071282]; cellular response to lithium ion [GO:0071285]; cellular response to mechanical stimulus [GO:0071260]; chemical synaptic transmission, postsynaptic [GO:0099565]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fat cell differentiation [GO:0045444]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; hypermethylation of CpG island [GO:0044027]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron maturation [GO:0014043]; negative regulation of neuron migration [GO:2001223]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of type B pancreatic cell development [GO:2000077]; organ morphogenesis [GO:0009887]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of axon extension [GO:0045773]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein localization to microtubule [GO:0035372]; protein phosphorylation [GO:0006468]; re-entry into mitotic cell cycle [GO:0000320]; regulation of cellular response to heat [GO:1900034]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of microtubule-based process [GO:0032886]; regulation of neuronal synaptic plasticity [GO:0048168]; response to activity [GO:0014823]; response to angiotensin [GO:1990776]; response to drug [GO:0042493]; response to epinephrine [GO:0071871]; response to estradiol [GO:0032355]; response to insulin [GO:0032868]; response to insulin-like growth factor stimulus [GO:1990418]; response to L-glutamate [GO:1902065]; response to ultrasound [GO:1990478]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]" comp140344_c0_seq1,1630,43.1902,1.04206335,6,150,,3.00E-49,Q8BLQ7,Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4),Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4),GO:0015171; GO:0016021,amino acid transmembrane transporter activity; integral to membrane,PF13520;PF13906;,,,,,,,,,CTR4_MOUSE,Mus musculus (Mouse), comp140345_c4_seq1,1570,44.3312,0.49519116,75,274,,5.00E-74,Q5ZMS6,Tudor domain-containing protein 3,Tudor domain-containing protein 3,GO:0003723; GO:0003682; GO:0016568; GO:0005737; GO:0006397; GO:0035064; GO:0005634; GO:0003713,RNA binding; chromatin binding; chromatin modification; cytoplasm; mRNA processing; methylated histone residue binding; nucleus; transcription coactivator activity,PF08585;PF06003;PF00627;,3.00E-44,CHOYP_TDRD3.1.2,,,,,,,TDRD3_CHICK,Gallus gallus (Chicken),chromatin modification [GO:0016568]; mRNA processing [GO:0006397] comp140346_c0_seq1,1691,39.385,0.38245945,192,1664,,4.00E-23,Q0II26,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1),Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1),GO:0060510; GO:0006915; GO:0005829; GO:0008285; GO:0005634; GO:0031398; GO:0006412,Type II pneumocyte differentiation; apoptotic process; cytosol; negative regulation of cell proliferation; nucleus; positive regulation of protein ubiquitination; translation,PF16780;PF00043;,,,,,,,,,AIMP2_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; negative regulation of cell proliferation [GO:0008285]; positive regulation of protein ubiquitination [GO:0031398]; translation [GO:0006412]; Type II pneumocyte differentiation [GO:0060510] comp140346_c0_seq3,1957,38.0685,0.48672294,171,203,,5.00E-34,A2VE58,Synaptogyrin-3,Synaptogyrin-3,GO:0030054; GO:0016021; GO:0031594; GO:0032411; GO:0008021,cell junction; integral to membrane; neuromuscular junction; positive regulation of transporter activity; synaptic vesicle,PF01284;,3.00E-39,CHOYP_LOC100373178.1.1,,,,,,,SNG3_BOVIN,Bos taurus (Bovine),positive regulation of transporter activity [GO:0032411]; substantia nigra development [GO:0021762] comp140348_c0_seq1,1215,38.5185,0.58011048,26,69,,,,,,,,,3.00E-23,CHOYP_TM129.1.1,,,,,,,,, comp140348_c0_seq3,1256,38.2962,0.59026438,10,167,,8.00E-136,Q0IJ33,Transmembrane protein 129,E3 ubiquitin-protein ligase TM129 (EC 6.3.2.-),GO:0016021,integral to membrane,PF10272;,,,,,,,,,TM129_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination [GO:0016567]; response to unfolded protein [GO:0006986] comp140350_c0_seq2,482,37.3444,1.21418321,40,22,,,,,,,,,2.00E-14,CHOYP_LOC100494344.3.3,,,,,,,,, comp140351_c0_seq1,1723,37.0284,1.10729126,2003,15961,,,,,,,,,1.00E-12,CHOYP_LOC587133.1.1,2.00E-33,ruditapes_c19672,,,,,,, comp140352_c2_seq7,1447,39.6683,0.30095499,11,55,,6.00E-149,O42870,Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS),Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS),GO:0005524; GO:0002181; GO:0005829; GO:0004826; GO:0009328; GO:0006432; GO:0000049,ATP binding; cytoplasmic translation; cytosol; phenylalanine-tRNA ligase activity; phenylalanine-tRNA ligase complex; phenylalanyl-tRNA aminoacylation; tRNA binding,PF01409;,,,,,,,,,SYFA_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translation [GO:0002181]; phenylalanyl-tRNA aminoacylation [GO:0006432] comp140352_c2_seq9,1435,39.5819,0.28691323,3,98,,0,Q6AZG6,Phenylalanine--tRNA ligase alpha subunit A (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit A) (PheRS),Phenylalanine--tRNA ligase alpha subunit A (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit A) (PheRS),GO:0005524; GO:0005737; GO:0004826; GO:0006432; GO:0000049,ATP binding; cytoplasm; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding,PF01409;,1.00E-155,CHOYP_SYFA.1.1,,,2.00E-140,FP000294.p.cg.6,9,,SYFAA_XENLA,Xenopus laevis (African clawed frog),phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] comp140354_c0_seq1,2208,37.1377,0.63122189,759,4351,,4.00E-65,Q9CQ60,6-phosphogluconolactonase (6PGL) (EC 3.1.1.31),6-phosphogluconolactonase (6PGL) (EC 3.1.1.31),GO:0017057; GO:0005737; GO:0006098,6-phosphogluconolactonase activity; cytoplasm; pentose-phosphate shunt,PF01182;,2.00E-29,CHOYP_LOC100371875.1.1,,,,,,,6PGL_MOUSE,Mus musculus (Mouse),"carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]" comp140354_c1_seq11,785,45.0955,0.50100725,0,0,,1.00E-98,Q15024,Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8),Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8),GO:0000175; GO:0003723; GO:0005829; GO:0043928; GO:0000178; GO:0005730; GO:0006364,3'-5'-exoribonuclease activity; RNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; exosome (RNase complex); nucleolus; rRNA processing,PF01138;PF03725;,,,,,,,,,EXOS7_HUMAN,Homo sapiens (Human),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; regulation of mRNA stability [GO:0043488]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" comp140354_c1_seq15,774,42.7649,0.51670806,0,0,,8.00E-34,Q54VM4,Putative exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42),Putative exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42),GO:0003723; GO:0005737; GO:0000178; GO:0005730; GO:0006364,RNA binding; cytoplasm; exosome (RNase complex); nucleolus; rRNA processing,PF01138;PF03725;,,,,,,,,,EXOS7_DICDI,Dictyostelium discoideum (Slime mold),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" comp140354_c1_seq2,773,43.2083,0.49756181,0,0,,8.00E-34,Q54VM4,Putative exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42),Putative exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42),GO:0003723; GO:0005737; GO:0000178; GO:0005730; GO:0006364,RNA binding; cytoplasm; exosome (RNase complex); nucleolus; rRNA processing,PF01138;PF03725;,2.00E-67,CHOYP_EXOS7.1.1,,,,,,,EXOS7_DICDI,Dictyostelium discoideum (Slime mold),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" comp140354_c1_seq4,984,44.6138,0.48674803,0,0,,9.00E-120,Q15024,Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8),Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8),GO:0000175; GO:0003723; GO:0005829; GO:0043928; GO:0000178; GO:0005730; GO:0006364,3'-5'-exoribonuclease activity; RNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; exosome (RNase complex); nucleolus; rRNA processing,PF01138;PF03725;,,,,,,,,,EXOS7_HUMAN,Homo sapiens (Human),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; regulation of mRNA stability [GO:0043488]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" comp140354_c1_seq5,983,44.9644,0.47249918,0,0,,1.00E-45,Q5JIR7,Exosome complex component Rrp42,Exosome complex component Rrp42,GO:0000175; GO:0006401; GO:0005737; GO:0000178; GO:0090305,3'-5'-exoribonuclease activity; RNA catabolic process; cytoplasm; exosome (RNase complex); nucleic acid phosphodiester bond hydrolysis,PF01138;PF03725;,2.00E-102,CHOYP_EXOS7.1.1,,,,,,,ECX2_PYRKO,Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)),RNA catabolic process [GO:0006401] comp140356_c0_seq1,1641,42.3522,0.34332515,260,1237,,2.00E-79,P43351,DNA repair protein RAD52 homolog,DNA repair protein RAD52 homolog,GO:0003677; GO:0000730; GO:0006312; GO:0005654; GO:0007131,DNA binding; DNA recombinase assembly; mitotic recombination; nucleoplasm; reciprocal meiotic recombination,PF04098;,2.00E-110,CHOYP_RAD52.1.1,,,,,,,RAD52_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; protein sumoylation [GO:0016925]; regulation of nucleotide-excision repair [GO:2000819] comp140357_c0_seq1,2895,36.3731,0.71836203,11,285,,2.00E-16,Q9NS37,CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei),CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei),GO:0003677; GO:0045814; GO:0045892; GO:0005634; GO:0051090; GO:0009615; GO:0043565; GO:0003700; GO:0006351,"DNA binding; negative regulation of gene expression, epigenetic; negative regulation of transcription, DNA-dependent; nucleus; regulation of sequence-specific DNA binding transcription factor activity; response to virus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00170;,,,,,,,,,ZHANG_HUMAN,Homo sapiens (Human),"negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]" comp140357_c0_seq3,2687,36.8813,0.75554506,69,266,,2.00E-16,Q9NS37,CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei),CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei),GO:0003677; GO:0045814; GO:0045892; GO:0005634; GO:0051090; GO:0009615; GO:0043565; GO:0003700; GO:0006351,"DNA binding; negative regulation of gene expression, epigenetic; negative regulation of transcription, DNA-dependent; nucleus; regulation of sequence-specific DNA binding transcription factor activity; response to virus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00170;,,,,,,,,,ZHANG_HUMAN,Homo sapiens (Human),"negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]" comp140358_c0_seq1,2375,34.5684,0.60966713,0,0,,1.00E-28,Q9H8Y5,Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744),Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744),GO:0046872,metal ion binding,,2.00E-30,CHOYP_ANKZF1.1.1,,,,,,,ANKZ1_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mitochondria-associated ubiquitin-dependent protein catabolic process [GO:0072671]; nucleus-associated proteasomal ubiquitin-dependent protein catabolic process [GO:0071630] comp140358_c0_seq3,2441,34.4121,0.59792967,0,0,,,,,,,,,2.00E-30,CHOYP_ANKZF1.1.1,,,,,,,,, comp140360_c2_seq3,1054,42.7894,0.53686337,5,10,,5.00E-68,Q4V838,Protein LTV1 homolog,Protein LTV1 homolog,,,PF04180;,,,,,,,,,LTV1_XENLA,Xenopus laevis (African clawed frog), comp140360_c2_seq4,1084,43.6347,0.58832928,9,72,,2.00E-63,Q5R8B2,Protein LTV1 homolog,Protein LTV1 homolog,,,PF04180;,6.00E-45,CHOYP_LTV1.1.1,2.00E-41,ruditapes_c28835,,,,,LTV1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140361_c0_seq1,3760,41.3564,0.4742592,13,3,,1.00E-158,Q91V83,TELO2-interacting protein 1 homolog,TELO2-interacting protein 1 homolog,GO:0031931; GO:0031932; GO:0005737; GO:0032006,TORC1 complex; TORC2 complex; cytoplasm; regulation of TOR signaling cascade,,,,,,,,,,TTI1_MOUSE,Mus musculus (Mouse),regulation of TOR signaling [GO:0032006] comp140361_c0_seq2,3647,41.7329,0.4738155,0,0,,1.00E-06,O94600,TEL2-interacting protein 1,TEL2-interacting protein 1,GO:0070209; GO:0005737,ASTRA complex; cytoplasm,,,,,,,,,,TTI1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338] comp140361_c0_seq3,1696,39.1509,0.55912817,0,0,,1.00E-69,O43156,TELO2-interacting protein 1 homolog (Protein SMG10),TELO2-interacting protein 1 homolog (Protein SMG10),GO:0031931; GO:0031932; GO:0005737; GO:0032006,TORC1 complex; TORC2 complex; cytoplasm; regulation of TOR signaling cascade,,,,,,,,,,TTI1_HUMAN,Homo sapiens (Human),regulation of TOR signaling [GO:0032006] comp140363_c0_seq1,1207,43.2477,0.4822216,220,1247,,1.00E-137,Q9UET6,Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1),Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1),GO:0001510; GO:0005737; GO:0008168; GO:0008033,RNA methylation; cytoplasm; methyltransferase activity; tRNA processing,PF01728;,4.00E-142,CHOYP_LOC100370046.1.1,1.00E-83,ruditapes_c14886,,,,,RRMJ1_HUMAN,Homo sapiens (Human),cytoplasmic translation [GO:0002181]; tRNA methylation [GO:0030488]; tRNA nucleoside ribose methylation [GO:0002128] comp140365_c4_seq2,845,40.8284,0.80984729,0,28,,7.00E-43,Q96SL1,Disrupted in renal carcinoma protein 2 (Disrupted in renal cancer protein 2),Disrupted in renal carcinoma protein 2 (Disrupted in renal cancer protein 2),GO:0016021; GO:0005765; GO:0006810,integral to membrane; lysosomal membrane; transport,,,,,,,,,,DIRC2_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp140366_c1_seq3,1403,36.9922,0.36241629,68,306,,3.00E-67,Q5XGY9,Meiotic nuclear division protein 1 homolog,Meiotic nuclear division protein 1 homolog,GO:0006310; GO:0007126; GO:0005634,DNA recombination; meiosis; nucleus,PF03962;,4.00E-67,CHOYP_LOC100376369.1.1,,,,,,,MND1_XENLA,Xenopus laevis (African clawed frog),DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321] comp140367_c0_seq1,1876,41.6844,0.4573317,34,99,,2.00E-33,P72835,Uncharacterized protein slr1300,Uncharacterized protein slr1300,GO:0050660; GO:0016709; GO:0006744,"flavin adenine dinucleotide binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; ubiquinone biosynthetic process",PF01494;,7.00E-60,CHOYP_LOC100889564.1.1,,,,,,,Y1300_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),secondary metabolite biosynthetic process [GO:0044550]; ubiquinone biosynthetic process [GO:0006744] comp140367_c0_seq2,1862,41.5682,0.45051703,29,60,,8.00E-150,Q6DF46,Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6),"Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6)",GO:0005794; GO:0042995; GO:0050660; GO:0016709; GO:0006744,"Golgi apparatus; cell projection; flavin adenine dinucleotide binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; ubiquinone biosynthetic process",PF01494;,2.00E-61,CHOYP_LOC100889564.1.1,,,,,,,COQ6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),secondary metabolite biosynthetic process [GO:0044550]; ubiquinone biosynthetic process [GO:0006744] comp140369_c4_seq1,815,44.7853,0.6620493,13,15,,3.00E-09,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp140369_c4_seq2,642,43.4579,0.64456208,0,0,,1.00E-09,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,2.00E-11,CHOYP_LOC100892567.6.8,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp140374_c0_seq1,1998,47.047,0.463666,0,0,,3.00E-34,B0W2W6,Protein maelstrom homolog,Protein maelstrom homolog,GO:0003677; GO:0030154; GO:0005737; GO:0031047; GO:0007126; GO:0007275; GO:0005634,DNA binding; cell differentiation; cytoplasm; gene silencing by RNA; meiosis; multicellular organismal development; nucleus,PF09011;PF13017;,,,,,,,,,MAEL_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275] comp140374_c0_seq3,1705,47.0968,0.41392325,0,0,,,,,,,,,6.00E-41,CHOYP_BRAFLDRAFT_121310.1.1,,,,,,,,, comp140374_c0_seq4,1955,47.1611,0.47181139,0,0,,4.00E-46,Q4R786,Protein maelstrom homolog,Protein maelstrom homolog,GO:0003677; GO:0043046; GO:0030154; GO:0031047; GO:0007126; GO:0007275; GO:0005634; GO:0071547; GO:0034587; GO:0007283,DNA binding; DNA methylation involved in gamete generation; cell differentiation; gene silencing by RNA; meiosis; multicellular organismal development; nucleus; piP-body; piRNA metabolic process; spermatogenesis,PF09011;PF13017;,,,,,,,,,MAEL_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp140374_c0_seq6,1662,47.2323,0.42238374,0,0,,,,,,,,,6.00E-41,CHOYP_BRAFLDRAFT_121310.1.1,,,,,,,,, comp140374_c0_seq7,1529,45.2583,0.45025748,0,0,,1.00E-34,B0W2W6,Protein maelstrom homolog,Protein maelstrom homolog,GO:0003677; GO:0030154; GO:0005737; GO:0031047; GO:0007126; GO:0007275; GO:0005634,DNA binding; cell differentiation; cytoplasm; gene silencing by RNA; meiosis; multicellular organismal development; nucleus,PF09011;PF13017;,,,,,,,,,MAEL_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275] comp140374_c0_seq8,1486,45.3567,0.46168675,0,0,,7.00E-47,Q4R786,Protein maelstrom homolog,Protein maelstrom homolog,GO:0003677; GO:0043046; GO:0030154; GO:0031047; GO:0007126; GO:0007275; GO:0005634; GO:0071547; GO:0034587; GO:0007283,DNA binding; DNA methylation involved in gamete generation; cell differentiation; gene silencing by RNA; meiosis; multicellular organismal development; nucleus; piP-body; piRNA metabolic process; spermatogenesis,PF09011;PF13017;,,,,,,,,,MAEL_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp140376_c0_seq3,568,39.9648,0.4436315,44,417,,2.00E-41,Q9DCG9,tRNA methyltransferase 112 homolog (TRM112-like protein),Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog),GO:0043234; GO:0008276,protein complex; protein methyltransferase activity,PF03966;,,,,,,,,,TR112_MOUSE,Mus musculus (Mouse),peptidyl-glutamine methylation [GO:0018364]; rRNA (guanine-N7)-methylation [GO:0070476]; tRNA methylation [GO:0030488] comp140377_c0_seq1,1556,40.8098,0.56121614,3,110,,5.00E-36,Q8TF72,Protein Shroom3 (Shroom-related protein) (hShrmL),Protein Shroom3 (Shroom-related protein) (hShrmL),GO:0030036; GO:0005912; GO:0043296; GO:0016324; GO:0045176; GO:0000902; GO:0043482; GO:0002066; GO:0005737; GO:0005856; GO:0005874; GO:0001843; GO:0007389; GO:0008360,actin cytoskeleton organization; adherens junction; apical junction complex; apical plasma membrane; apical protein localization; cell morphogenesis; cellular pigment accumulation; columnar/cuboidal epithelial cell development; cytoplasm; cytoskeleton; microtubule; neural tube closure; pattern specification process; regulation of cell shape,PF08688;PF08687;PF00595;,,,,,,,,,SHRM3_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; cell morphogenesis [GO:0000902]; cellular pigment accumulation [GO:0043482]; epithelial cell development [GO:0002064]; neural tube closure [GO:0001843]; pattern specification process [GO:0007389]; regulation of cell shape [GO:0008360] comp140377_c0_seq2,3385,34.8892,0.51603984,147,1735,,2.00E-12,Q8TF72,Protein Shroom3 (Shroom-related protein) (hShrmL),Protein Shroom3 (Shroom-related protein) (hShrmL),GO:0030036; GO:0005912; GO:0043296; GO:0016324; GO:0045176; GO:0000902; GO:0043482; GO:0002066; GO:0005737; GO:0005856; GO:0005874; GO:0001843; GO:0007389; GO:0008360,actin cytoskeleton organization; adherens junction; apical junction complex; apical plasma membrane; apical protein localization; cell morphogenesis; cellular pigment accumulation; columnar/cuboidal epithelial cell development; cytoplasm; cytoskeleton; microtubule; neural tube closure; pattern specification process; regulation of cell shape,PF08688;PF08687;PF00595;,,,,,,,,,SHRM3_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; cell morphogenesis [GO:0000902]; cellular pigment accumulation [GO:0043482]; epithelial cell development [GO:0002064]; neural tube closure [GO:0001843]; pattern specification process [GO:0007389]; regulation of cell shape [GO:0008360] comp140384_c2_seq1,2670,35.5056,0.45188153,4658,11223,,8.00E-67,Q9H3L0,"Methylmalonic aciduria and homocystinuria type D protein, mitochondrial","Methylmalonic aciduria and homocystinuria type D protein, mitochondrial",GO:0009235; GO:0005829; GO:0005739,cobalamin metabolic process; cytosol; mitochondrion,PF10229;,,,5.00E-67,ruditapes_c8812,,,,,MMAD_HUMAN,Homo sapiens (Human),cobalamin metabolic process [GO:0009235] comp140387_c1_seq1,2090,40.2871,0.60088983,40,34,,,,,,,,,3.00E-58,CHOYP_LOC100366927.1.1,,,,,,,,, comp140387_c1_seq2,1812,42.2185,0.56636602,7,8,,5.00E-35,P44121,DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP]),DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP]),GO:0005524; GO:0003910; GO:0051103; GO:0006310; GO:0006260; GO:0046872,ATP binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; DNA recombination; DNA replication; metal ion binding,PF01068;PF14743;,1.00E-55,CHOYP_LOC100366927.1.1,,,,,,,DNLI_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260] comp140389_c0_seq1,1922,33.8189,0.64966234,1737,13372,,4.00E-35,P91303,Probable V-type proton ATPase subunit G (V-ATPase subunit G) (Vacuolar proton pump subunit G),Probable V-type proton ATPase subunit G (V-ATPase subunit G) (Vacuolar proton pump subunit G),GO:0006754; GO:0015078; GO:0016820; GO:0043068; GO:0012501; GO:0016471,"ATP biosynthetic process; hydrogen ion transmembrane transporter activity; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; positive regulation of programmed cell death; programmed cell death; vacuolar proton-transporting V-type ATPase complex",,6.00E-29,CHOYP_VATG.1.2,,,,,,,VATG_CAEEL,Caenorhabditis elegans,ATP biosynthetic process [GO:0006754]; positive regulation of programmed cell death [GO:0043068]; programmed cell death [GO:0012501]; proton transport [GO:0015992] comp140391_c0_seq1,1696,41.7453,0.67126528,8,69,,2.00E-123,Q02589,[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),GO:0003875; GO:0006464; GO:0000287; GO:0051725,ADP-ribosylarginine hydrolase activity; cellular protein modification process; magnesium ion binding; protein de-ADP-ribosylation,PF03747;,,,,,,,,,ADPRH_RAT,Rattus norvegicus (Rat),cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725] comp140391_c0_seq2,1349,40.5486,0.68428445,0,0,,5.00E-90,Q02589,[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),GO:0003875; GO:0006464; GO:0000287; GO:0051725,ADP-ribosylarginine hydrolase activity; cellular protein modification process; magnesium ion binding; protein de-ADP-ribosylation,PF03747;,6.00E-40,CHOYP_BRAFLDRAFT_212086.9.11,,,,,,,ADPRH_RAT,Rattus norvegicus (Rat),cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725] comp140394_c1_seq1,1305,46.8966,0.5025496,132,317,,0,P35505,Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase),Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase),GO:0006559; GO:0006527; GO:0004334; GO:0046872; GO:0006572,L-phenylalanine catabolic process; arginine catabolic process; fumarylacetoacetase activity; metal ion binding; tyrosine catabolic process,PF01557;PF09298;,5.00E-167,CHOYP_FAAA.1.1,,,,,,,FAAA_MOUSE,Mus musculus (Mouse),arginine catabolic process [GO:0006527]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp140395_c0_seq1,2325,39.2258,0.62642664,838,4476,,8.00E-60,Q5ZJH7,Protein CNPPD1,Protein CNPPD1,GO:0016021; GO:0000079,integral to membrane; regulation of cyclin-dependent protein serine/threonine kinase activity,PF08613;,2.00E-42,CHOYP_LOC100372380.1.1,,,,,,,CNPD1_CHICK,Gallus gallus (Chicken),regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] comp140397_c3_seq5,912,47.0395,0.41771292,31,20,,4.00E-58,Q8BQM9,Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09497;PF12145;PF12144;,1.00E-20,CHOYP_MD12L.1.1,,,,,,,MD12L_MOUSE,Mus musculus (Mouse), comp140398_c0_seq1,3259,42.0374,0.54493559,630,3664,,0,Q9H0A0,N-acetyltransferase 10 (EC 2.3.1.-),RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10),GO:0005524; GO:0008080; GO:0005730; GO:0005634,ATP binding; N-acetyltransferase activity; nucleolus; nucleus,PF08351;PF13718;PF05127;PF13725;,0,CHOYP_LOC100375877.1.1,,,,,,,NAT10_HUMAN,Homo sapiens (Human),negative regulation of telomere maintenance via telomerase [GO:0032211]; rRNA modification [GO:0000154]; tRNA processing [GO:0008033] comp140399_c0_seq1,3119,38.4739,0.54518404,895,8318,,0,Q04451,Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase) (GlyRS),Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase) (GlyRS),GO:0005524; GO:0005737; GO:0015966; GO:0004820; GO:0006426; GO:0046983,ATP binding; cytoplasm; diadenosine tetraphosphate biosynthetic process; glycine-tRNA ligase activity; glycyl-tRNA aminoacylation; protein dimerization activity,PF03129;PF00587;PF00458;,0,CHOYP_LOC100123216.1.1,,,,,,,SYG_BOMMO,Bombyx mori (Silk moth),diadenosine tetraphosphate biosynthetic process [GO:0015966]; glycyl-tRNA aminoacylation [GO:0006426] comp140402_c0_seq1,643,30.4821,0.88733654,51,5,,,,,,,,,5.00E-18,CHOYP_contig_010379,,,,,,,,, comp140402_c0_seq2,2139,34.6891,0.70129715,885,20,,6.00E-132,A7S8T5,Coiled-coil domain-containing protein 42 homolog,Coiled-coil domain-containing protein 42 homolog,,,PF13863;,,,,,,,,,CCD42_NEMVE,Nematostella vectensis (Starlet sea anemone), comp140402_c0_seq3,1356,37.7581,0.65023608,4,63,,1.00E-135,A7S8T5,Coiled-coil domain-containing protein 42 homolog,Coiled-coil domain-containing protein 42 homolog,,,PF13863;,7.00E-153,CHOYP_CCD42.1.1,,,,,,,CCD42_NEMVE,Nematostella vectensis (Starlet sea anemone), comp140405_c1_seq1,1347,42.539,0.37288156,29,193,,7.00E-72,Q4R3J0,RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1),RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1),GO:0005524; GO:0006396; GO:0003963; GO:0005654,ATP binding; RNA processing; RNA-3'-phosphate cyclase activity; nucleoplasm,PF01137;PF05189;,8.00E-19,CHOYP_RTCA.1.1,,,,,,,RTCA_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),RNA processing [GO:0006396] comp140406_c2_seq6,1468,34.0599,0.75972561,1028,5805,,6.00E-45,Q7ZUG0,Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE),Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE),GO:0003723; GO:0000398; GO:0005681,"RNA binding; mRNA splicing, via spliceosome; spliceosomal complex",PF01423;,1.00E-48,CHOYP_RUXE.3.4,9.00E-80,ruditapes2_c56,,,,,RUXE_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),spliceosomal snRNP assembly [GO:0000387] comp140407_c0_seq1,1633,36.6197,0.44281859,69,321,,3.00E-77,O18638,Out at first protein,Out at first protein,GO:0007275,multicellular organismal development,PF14941;,3.00E-26,CHOYP_LOC100367385.1.1,,,,,,,OAF_DROVI,Drosophila virilis (Fruit fly),multicellular organism development [GO:0007275] comp140407_c0_seq3,1359,39.5143,0.60520127,1,95,,1.00E-73,Q5RBJ7,Transmembrane 6 superfamily member 1,Transmembrane 6 superfamily member 1,GO:0016021,integral to membrane,,1.00E-11,CHOYP_LOC100376054.1.1,,,,,,,TM6S1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140409_c4_seq3,4207,42.144,0.55036445,3,8,,0,Q9EPE9,Probable cation-transporting ATPase 13A1 (CATP) (EC 3.6.3.-),Manganese-transporting ATPase 13A1 (CATP) (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00122;,0,CHOYP_ATP13A.1.1,,,,,,,AT131_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp140409_c4_seq4,4168,42.1785,0.56996789,3,9,,0,Q9LT02,Probable cation-transporting ATPase (EC 3.6.3.-),Probable manganese-transporting ATPase PDR2 (EC 3.6.3.-) (Protein MALE GAMETOGENESIS IMPAIRED ANTHERS) (Protein PHOSPHATE DEFICIENCY RESPONSE 2),GO:0005524; GO:0019829; GO:0006875; GO:0016036; GO:0005783; GO:0016021; GO:0010073; GO:0046872; GO:0005886; GO:0009846; GO:0010152; GO:0048867,ATP binding; cation-transporting ATPase activity; cellular metal ion homeostasis; cellular response to phosphate starvation; endoplasmic reticulum; integral to membrane; meristem maintenance; metal ion binding; plasma membrane; pollen germination; pollen maturation; stem cell fate determination,PF00122;,0,CHOYP_ATP13A.1.1,,,,,,,ATY1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular metal ion homeostasis [GO:0006875]; cellular response to phosphate starvation [GO:0016036]; meristem maintenance [GO:0010073]; pollen germination [GO:0009846]; pollen maturation [GO:0010152]; stem cell fate determination [GO:0048867] comp140409_c4_seq5,3422,41.6423,0.53581241,0,0,,0,Q9EPE9,Probable cation-transporting ATPase 13A1 (CATP) (EC 3.6.3.-),Manganese-transporting ATPase 13A1 (CATP) (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00122;,,,,,,,,,AT131_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp140409_c4_seq6,3383,41.6199,0.55542862,0,0,,3.00E-157,O14072,Cation-transporting ATPase 4 (EC 3.6.3.-),Manganese-transporting ATPase 4 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0070588; GO:0019829; GO:0006874; GO:0030176; GO:0046872,ATP binding; ATP catabolic process; calcium ion transmembrane transport; cation-transporting ATPase activity; cellular calcium ion homeostasis; integral to endoplasmic reticulum membrane; metal ion binding,PF00122;,,,,,,,,,ATC4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874] comp140409_c4_seq7,2564,39.1576,0.55388943,0,0,,1.00E-08,P37278,Probable calcium-transporting ATPase (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0005886,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; plasma membrane,PF00689;PF00690;PF00122;,,,,,,,,,ATCL_SYNE7,Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2), comp140409_c4_seq9,2603,39.1471,0.51708115,0,0,,2.00E-159,Q9EPE9,Probable cation-transporting ATPase 13A1 (CATP) (EC 3.6.3.-),Manganese-transporting ATPase 13A1 (CATP) (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00122;,8.00E-130,CHOYP_ATP13A.1.1,,,,,,,AT131_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp140410_c0_seq2,438,45.6621,0.58569681,0,0,,,,,,,,,2.00E-15,CHOYP_LOC100376265.3.4,,,,,,,,, comp140410_c0_seq3,960,46.0417,0.53269432,24,145,,9.00E-111,B5X3C1,Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),GO:0005975; GO:0004336; GO:0006683; GO:0005764,carbohydrate metabolic process; galactosylceramidase activity; galactosylceramide catabolic process; lysosome,PF02057;,,,,,,,,,GALC_SALSA,Salmo salar (Atlantic salmon),carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683] comp140415_c0_seq1,2274,32.4099,0.62021085,4153,12339,,3.00E-89,Q9EQX9,Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Bendless-like ubiquitin-conjugating enzyme) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N),Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N),GO:0005524; GO:0006281; GO:0035370; GO:0070534; GO:0000151; GO:0006511; GO:0004842,ATP binding; DNA repair; UBC13-UEV1A complex; protein K63-linked ubiquitination; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00179;,3.00E-91,CHOYP_UBE2N.1.1,,,,,,,UBE2N_RAT,Rattus norvegicus (Rat),DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; histone ubiquitination [GO:0016574]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140417_c0_seq1,1546,41.7206,0.40265504,38,21,,2.00E-16,Q3UQ28,Peroxidasin homolog (EC 1.11.1.7),Peroxidasin homolog (EC 1.11.1.7),GO:0005783; GO:0031012; GO:0030198; GO:0005201; GO:0005615; GO:0020037; GO:0042744; GO:0046872; GO:0004601; GO:0005578,endoplasmic reticulum; extracellular matrix; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity; proteinaceous extracellular matrix,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_MOUSE,Mus musculus (Mouse),extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979] comp140417_c0_seq2,3093,39.2499,0.49869421,99,251,,1.00E-35,P34082,Fasciclin-2 (Fasciclin II) (FAS II),Fasciclin-2 (Fasciclin II) (FAS II),GO:0001746; GO:0031225; GO:0007413; GO:0048149; GO:0048667; GO:0005737; GO:0007156; GO:0048803; GO:0016021; GO:0097482; GO:0016319; GO:0042059; GO:0031594; GO:0007528; GO:0008355; GO:0045211; GO:0048786; GO:0042734; GO:0036062; GO:0008360; GO:0008582; GO:0035158; GO:0035159; GO:0007614; GO:0072553; GO:0061174,"Bolwig's organ morphogenesis; anchored to membrane; axonal fasciculation; behavioral response to ethanol; cell morphogenesis involved in neuron differentiation; cytoplasm; homophilic cell adhesion; imaginal disc-derived male genitalia morphogenesis; integral to membrane; muscle cell postsynaptic density; mushroom body development; negative regulation of epidermal growth factor receptor signaling pathway; neuromuscular junction; neuromuscular junction development; olfactory learning; postsynaptic membrane; presynaptic active zone; presynaptic membrane; presynaptic periactive zone; regulation of cell shape; regulation of synaptic growth at neuromuscular junction; regulation of tube diameter, open tracheal system; regulation of tube length, open tracheal system; short-term memory; terminal button organization; type I terminal bouton",PF00041;PF07679;,,,,,,,,,FAS2_DROME,Drosophila melanogaster (Fruit fly),"axonal fasciculation [GO:0007413]; behavioral response to ethanol [GO:0048149]; Bolwig's organ morphogenesis [GO:0001746]; cell morphogenesis involved in neuron differentiation [GO:0048667]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; learning [GO:0007612]; learning or memory [GO:0007611]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron remodeling [GO:1904800]; neuromuscular junction development [GO:0007528]; neuron recognition [GO:0008038]; olfactory learning [GO:0008355]; photoreceptor cell axon guidance [GO:0072499]; regulation of cell shape [GO:0008360]; regulation of synapse structure or activity [GO:0050803]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of tube architecture, open tracheal system [GO:0035152]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; short-term memory [GO:0007614]; synapse organization [GO:0050808]; terminal button organization [GO:0072553]" comp140418_c0_seq1,1467,39.6046,0.52559996,694,4665,,6.00E-162,A6QQ21,COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6),COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6),GO:0008180; GO:0005737,COP9 signalosome; cytoplasm,PF01398;PF13012;,9.00E-165,CHOYP_LOC592528.1.2,3.00E-117,ruditapes_c11976,,,,,CSN6_BOVIN,Bos taurus (Bovine),cullin deneddylation [GO:0010388] comp140421_c0_seq1,1730,35.5491,0.5456059,39,330,,3.00E-76,Q9Y2Q3,Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13),Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13),GO:0006749; GO:0004602; GO:0004364; GO:0005743; GO:0005759; GO:0005777; GO:0015035,glutathione metabolic process; glutathione peroxidase activity; glutathione transferase activity; mitochondrial inner membrane; mitochondrial matrix; peroxisome; protein disulfide oxidoreductase activity,PF01323;,2.00E-48,CHOYP_BRAFLDRAFT_281070.1.1,,,,,,,GSTK1_HUMAN,Homo sapiens (Human),epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749] comp140421_c0_seq2,1722,35.3078,0.49560261,19,224,,1.00E-28,Q09652,Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST class-kappa),Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST class-kappa),GO:0004364; GO:0005777; GO:0015035,glutathione transferase activity; peroxisome; protein disulfide oxidoreductase activity,PF01323;,,,,,,,,,GSTK1_CAEEL,Caenorhabditis elegans,innate immune response [GO:0045087] comp140424_c0_seq2,475,40,0.31772307,34,360,,6.00E-38,Q9D1M4,Eukaryotic translation elongation factor 1 epsilon-1 (Elongation factor p18) (Multisynthase complex auxiliary component p18),Eukaryotic translation elongation factor 1 epsilon-1 (Elongation factor p18) (Multisynthase complex auxiliary component p18),GO:0006281; GO:0017101; GO:0005737; GO:0009790; GO:0008285; GO:0005634; GO:0043517; GO:0043065; GO:2001235; GO:0006412,"DNA repair; aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; embryo development; negative regulation of cell proliferation; nucleus; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of apoptotic process; positive regulation of apoptotic signaling pathway; translation",PF00043;,,,8.00E-62,ruditapes_c7149,,,,,MCA3_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; embryo development [GO:0009790]; glutathione metabolic process [GO:0006749]; negative regulation of cell proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cellular senescence [GO:2000774]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]" comp140426_c1_seq1,791,43.2364,0.3560541,0,0,,,,,,,,,8.00E-29,CHOYP_VTA1.1.1,,,,,,,,, comp140426_c1_seq2,1755,38.8034,0.40904163,65,590,,7.00E-34,Q9NP79,Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1),Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1),GO:0005829; GO:0016197; GO:0010008; GO:0015031; GO:0016032,cytosol; endosomal transport; endosome membrane; protein transport; viral process,,,,,,,,,,VTA1_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; endosomal transport [GO:0016197]; ESCRT III complex disassembly [GO:1904903]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; protein transport [GO:0015031]; viral budding [GO:0046755]; viral life cycle [GO:0019058] comp140427_c2_seq2,1641,42.535,0.61061551,53,32,,4.00E-62,Q8NWQ4,L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),GO:0004794; GO:0070689; GO:0000166; GO:0030170,L-threonine ammonia-lyase activity; L-threonine catabolic process to propionate; nucleotide binding; pyridoxal phosphate binding,PF00291;,8.00E-128,CHOYP_LOC100375322.1.1,,,,,,,TDCB_STAAW,Staphylococcus aureus (strain MW2),L-threonine catabolic process to propionate [GO:0070689] comp140427_c2_seq3,1619,42.6807,0.60913729,32,80,,9.00E-61,Q7A5L8,L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),GO:0004794; GO:0070689; GO:0000166; GO:0030170,L-threonine ammonia-lyase activity; L-threonine catabolic process to propionate; nucleotide binding; pyridoxal phosphate binding,PF00291;,,,,,,,,,TDCB_STAAN,Staphylococcus aureus (strain N315),L-threonine catabolic process to propionate [GO:0070689] comp140430_c0_seq2,1853,44.5764,0.42573022,94,401,,0,Q8BFX3,BTB/POZ domain-containing protein KCTD3,BTB/POZ domain-containing protein KCTD3,GO:0051260,protein homooligomerization,PF02214;,1.00E-169,CHOYP_KCTD3.1.1,,,,,,,KCTD3_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp140435_c0_seq1,1605,43.8629,0.39560563,133,384,,0,Q922K7,Putative ribosomal RNA methyltransferase NOP2 (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120),Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120),GO:0003723; GO:0008757; GO:0005730; GO:0006364,RNA binding; S-adenosylmethionine-dependent methyltransferase activity; nucleolus; rRNA processing,PF01189;PF17125;PF08062;,0,CHOYP_LOC100207336.1.1,,,,,,,NOP2_MOUSE,Mus musculus (Mouse),maturation of LSU-rRNA [GO:0000470]; rRNA base methylation [GO:0070475] comp140436_c0_seq1,1670,35.8084,0.43897357,1574,6592,,5.00E-11,Q5NVS6,Apolipoprotein O-like (Protein FAM121A),MICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A),GO:0005576,extracellular region,PF09769;,,,,,,,,,APOOL_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cristae formation [GO:0042407] comp140437_c0_seq2,2909,32.4854,0.68008997,3306,6733,,4.00E-33,Q6B860,"28S ribosomal protein S14, mitochondrial (MRP-S14) (S14mt)","28S ribosomal protein S14, mitochondrial (MRP-S14) (S14mt)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF00253;,,,,,,,,,RT14_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp140438_c1_seq6,2726,36.8672,0.34587949,3299,20693,,0,P13952,G2/mitotic-specific cyclin-B,G2/mitotic-specific cyclin-B,GO:0051301; GO:0007067; GO:0005634; GO:0000079,cell division; mitosis; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,1.00E-121,CHOYP_CCNB.2.2,,,,,,,CCNB_SPISO,Spisula solidissima (Atlantic surf-clam),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp140440_c0_seq1,2207,36.3389,0.81601069,15,57,,3.00E-08,P69201,Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)],Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)],GO:0005634; GO:0005840; GO:0003735; GO:0006412,nucleus; ribosome; structural constituent of ribosome; translation,PF01020;PF00240;,,,,,,,,,RL40_LEIMA,Leishmania major,translation [GO:0006412] comp140440_c0_seq2,2143,36.3509,0.76754193,20,21,,,,,,,,,,,1.00E-55,ruditapes_c10382,,,,,,, comp140440_c0_seq3,2115,36.4066,0.79028158,0,0,,,,,,,,,,,2.00E-14,ruditapes_c27950,,,,,,, comp140440_c0_seq4,2179,36.2552,0.83050854,0,0,,3.00E-08,P69201,Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)],Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)],GO:0005634; GO:0005840; GO:0003735; GO:0006412,nucleus; ribosome; structural constituent of ribosome; translation,PF01020;PF00240;,,,,,,,,,RL40_LEIMA,Leishmania major,translation [GO:0006412] comp140441_c0_seq1,3085,36.5964,0.53968209,7111,48403,,0,Q9JLR1,Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2),Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2),GO:0005789; GO:0016021; GO:0015031; GO:0043022,endoplasmic reticulum membrane; integral to membrane; protein transport; ribosome binding,PF10559;PF00344;,0,CHOYP_COPA.1.1,8.00E-53,ruditapes_c15526,,,,,S61A2_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp140442_c3_seq2,374,37.9679,0.52742993,49,91,,,,,,,,,,,5.00E-13,ruditapes_c15855,,,,,,, comp140443_c1_seq2,963,38.6293,0.53500861,40,474,,,,,,,,,2.00E-19,CHOYP_BRAFLDRAFT_118054.1.1,,,,,,,,, comp140447_c0_seq3,1200,38.4167,0.57055756,114,188,,9.00E-32,Q7JUX9,Mitochondrial ribonuclease P protein 1 homolog (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),Mitochondrial ribonuclease P protein 1 homolog (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C),GO:0008168; GO:0005739; GO:0008033,methyltransferase activity; mitochondrion; tRNA processing,PF01746;,,,,,,,,,MRRP1_DROME,Drosophila melanogaster (Fruit fly),tRNA processing [GO:0008033] comp140451_c1_seq1,1104,42.9348,0.34146502,29,63,,1.00E-119,Q9HBK9,Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase),Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase),GO:0030791; GO:0018872; GO:0005829; GO:0030792; GO:0005739; GO:0009404,arsenite methyltransferase activity; arsonoacetate metabolic process; cytosol; methylarsonite methyltransferase activity; mitochondrion; toxin metabolic process,PF13847;,,,,,,,,,AS3MT_HUMAN,Homo sapiens (Human),arsonoacetate metabolic process [GO:0018872]; methylation [GO:0032259]; toxin metabolic process [GO:0009404] comp140451_c1_seq2,1082,43.2532,0.34438862,41,185,,4.00E-119,Q9HBK9,Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase),Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase),GO:0030791; GO:0018872; GO:0005829; GO:0030792; GO:0005739; GO:0009404,arsenite methyltransferase activity; arsonoacetate metabolic process; cytosol; methylarsonite methyltransferase activity; mitochondrion; toxin metabolic process,PF13847;,7.00E-101,CHOYP_BRAFLDRAFT_124020.1.1,,,,,,,AS3MT_HUMAN,Homo sapiens (Human),arsonoacetate metabolic process [GO:0018872]; methylation [GO:0032259]; toxin metabolic process [GO:0009404] comp140452_c1_seq1,436,40.1376,0.3433753,0,0,,2.00E-06,Q5RCJ3,Cullin-7 (CUL-7),Cullin-7 (CUL-7),GO:0005794; GO:0007030; GO:0031461; GO:0048471; GO:0050775; GO:0016567; GO:0006511,Golgi apparatus; Golgi organization; cullin-RING ubiquitin ligase complex; perinuclear region of cytoplasm; positive regulation of dendrite morphogenesis; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF03256;PF11515;PF00888;PF10557;,,,,,,,,,CUL7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),epithelial to mesenchymal transition [GO:0001837]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; placenta development [GO:0001890]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; regulation of mitotic nuclear division [GO:0007088]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140452_c1_seq3,1858,41.7653,0.44885325,0,0,,0,Q9WTX6,Cullin-1 (CUL-1),Cullin-1 (CUL-1),GO:0019005; GO:0031146; GO:0006915; GO:0008283; GO:0019048; GO:0009887; GO:0006513; GO:0004842,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; apoptotic process; cell proliferation; modulation by virus of host morphology or physiology; organ morphogenesis; protein monoubiquitination; ubiquitin-protein ligase activity,PF00888;PF10557;,0,CHOYP_CUL1.1.1,,,,,,,CUL1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; organ morphogenesis [GO:0009887]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032] comp140452_c1_seq4,1610,42.3602,0.46206213,0,0,,4.00E-14,Q9XIE8,Cullin-like protein 3 (Cullin-5) (AtCUL5),Cullin-like protein 3 (Cullin-5) (AtCUL5),GO:0031461; GO:0006511,cullin-RING ubiquitin ligase complex; ubiquitin-dependent protein catabolic process,PF00888;,,,,,,,,,CLL3_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp140452_c1_seq6,1408,39.9858,0.4271317,1,0,,1.00E-19,P53202,Cullin-3 (Cullin-B),Cullin-3 (Cullin-B),GO:0031463; GO:0042787; GO:0004842,Cul3-RING ubiquitin ligase complex; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00888;PF10557;,,,,,,,,,CUL3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140452_c1_seq9,594,44.1077,0.59221479,0,0,,,,,,,,,5.00E-106,CHOYP_CUL1.1.1,,,,,,,,, comp140453_c0_seq1,3374,38.2632,0.71251829,673,1301,,1.00E-11,P01266,Thyroglobulin (Tg),Thyroglobulin (Tg),GO:0005615; GO:0042446; GO:0015705; GO:0031641; GO:0007165; GO:0030878; GO:0006590,extracellular space; hormone biosynthetic process; iodide transport; regulation of myelination; signal transduction; thyroid gland development; thyroid hormone generation,PF00135;PF07699;PF00086;,4.00E-28,CHOYP_NID2.2.2,4.00E-31,ruditapes_c19972,,,,,THYG_HUMAN,Homo sapiens (Human),hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; transcytosis [GO:0045056] comp140455_c0_seq2,1755,39.7151,0.73842348,137,3738,,,,,,,,,,,1.00E-65,ruditapes_c15494,,,,,,, comp140456_c1_seq1,1191,28.7154,0.90687203,16,55,,2.00E-13,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp140456_c1_seq2,1142,28.5464,0.86877276,0,10,,4.00E-12,P16425,Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,Y2R2_DROME,Drosophila melanogaster (Fruit fly), comp140457_c0_seq2,2123,41.4979,0.50363417,133,438,,1.00E-94,Q6IRE4,Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101),Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101),GO:0000813; GO:0007049; GO:0051301; GO:0008333; GO:0031902; GO:0030374; GO:0005634; GO:0006513; GO:0015031; GO:0040008; GO:0043162; GO:0046755,ESCRT I complex; cell cycle; cell division; endosome to lysosome transport; late endosome membrane; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein monoubiquitination; protein transport; regulation of growth; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; viral budding,PF05743;PF09454;,7.00E-54,CHOYP_TS101.4.4,,,,,,,TS101_RAT,Rattus norvegicus (Rat),"cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosome to lysosome transport [GO:0008333]; keratinocyte differentiation [GO:0030216]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]" comp140460_c0_seq1,1924,42.8274,1.0147665,58,210,,7.00E-70,P19971,Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase),Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase),GO:0006260; GO:0001525; GO:0030154; GO:0006935; GO:0005829; GO:0000002; GO:0004645; GO:0005161; GO:0006206; GO:0046135; GO:0043097; GO:0006220; GO:0016154; GO:0009032,DNA replication; angiogenesis; cell differentiation; chemotaxis; cytosol; mitochondrial genome maintenance; phosphorylase activity; platelet-derived growth factor receptor binding; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; pyrimidine nucleotide metabolic process; pyrimidine-nucleoside phosphorylase activity; thymidine phosphorylase activity,PF02885;PF00591;PF07831;,,,,,,,,,TYPH_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220] comp140460_c0_seq2,1943,41.9969,1.01034585,70,230,,5.00E-56,C3MBH0,Thymidine phosphorylase (EC 2.4.2.4) (TdRPase),Thymidine phosphorylase (EC 2.4.2.4) (TdRPase),GO:0004645; GO:0006206; GO:0006213; GO:0016154; GO:0009032,phosphorylase activity; pyrimidine nucleobase metabolic process; pyrimidine nucleoside metabolic process; pyrimidine-nucleoside phosphorylase activity; thymidine phosphorylase activity,PF02885;PF00591;PF07831;,,,,,,,,,TYPH_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234),pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104] comp140460_c0_seq4,1611,44.879,1.06853245,4,84,,5.00E-135,P19971,Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase),Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase),GO:0006260; GO:0001525; GO:0030154; GO:0006935; GO:0005829; GO:0000002; GO:0004645; GO:0005161; GO:0006206; GO:0046135; GO:0043097; GO:0006220; GO:0016154; GO:0009032,DNA replication; angiogenesis; cell differentiation; chemotaxis; cytosol; mitochondrial genome maintenance; phosphorylase activity; platelet-derived growth factor receptor binding; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; pyrimidine nucleotide metabolic process; pyrimidine-nucleoside phosphorylase activity; thymidine phosphorylase activity,PF02885;PF00591;PF07831;,1.00E-49,CHOYP_BRAFLDRAFT_244533.2.2,,,,,,,TYPH_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220] comp140460_c0_seq6,1630,44.1104,1.06939877,0,0,,2.00E-104,Q5HM85,Pyrimidine-nucleoside phosphorylase (PYNP) (EC 2.4.2.2),Pyrimidine-nucleoside phosphorylase (PYNP) (Py-NPase) (EC 2.4.2.2),GO:0004645; GO:0006206; GO:0006213; GO:0016154,phosphorylase activity; pyrimidine nucleobase metabolic process; pyrimidine nucleoside metabolic process; pyrimidine-nucleoside phosphorylase activity,PF02885;PF00591;PF07831;,5.00E-16,CHOYP_LOC100215487.2.2,,,,,,,PDP_STAEQ,Staphylococcus epidermidis (strain ATCC 35984 / RP62A),pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213] comp140462_c1_seq2,1026,25.2437,0.85838888,43,101,,4.00E-15,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp140465_c0_seq1,4114,40.8119,0.20041026,49772,1566,,3.00E-14,Q8K561,Otoancorin,Otoancorin,GO:0031225; GO:0016324; GO:0007160; GO:0005578; GO:0007605; GO:0019226,anchored to membrane; apical plasma membrane; cell-matrix adhesion; proteinaceous extracellular matrix; sensory perception of sound; transmission of nerve impulse,,,,,,,,,,OTOAN_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226] comp140465_c1_seq12,1952,38.6783,0.99200026,0,0,,4.00E-29,P83088,"Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)","Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)",GO:0032580; GO:0036065; GO:0008417; GO:0016021; GO:0006486,Golgi cisterna membrane; fucosylation; fucosyltransferase activity; integral to membrane; protein glycosylation,PF17039;PF00852;,,,,,,,,,FUCTC_DROME,Drosophila melanogaster (Fruit fly),protein glycosylation [GO:0006486] comp140465_c1_seq14,1603,40.4242,1.14047471,4,653,female>male,1.00E-29,P83088,"Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)","Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)",GO:0032580; GO:0036065; GO:0008417; GO:0016021; GO:0006486,Golgi cisterna membrane; fucosylation; fucosyltransferase activity; integral to membrane; protein glycosylation,PF17039;PF00852;,,,,,,,,,FUCTC_DROME,Drosophila melanogaster (Fruit fly),protein glycosylation [GO:0006486] comp140469_c0_seq10,945,43.3862,0.67557028,0,0,,9.00E-47,Q18685,Protein unc-112 (Mitogen-inducible mig-2 protein-like) (Uncoordinated protein 112),Protein unc-112 (Mitogen-inducible mig-2 protein-like) (Uncoordinated protein 112),GO:0031430; GO:0050839; GO:0007160; GO:0030055; GO:0040011; GO:0007517; GO:0005543; GO:0005886; GO:0055120; GO:0005198,M band; cell adhesion molecule binding; cell-matrix adhesion; cell-substrate junction; locomotion; muscle organ development; phospholipid binding; plasma membrane; striated muscle dense body; structural molecule activity,PF00373;PF00169;,2.00E-38,CHOYP_LOC100366451.1.1,,,,,,,UN112_CAEEL,Caenorhabditis elegans,cell-matrix adhesion [GO:0007160]; establishment of protein localization to organelle [GO:0072594]; hermaphrodite genitalia morphogenesis [GO:0048815]; locomotion [GO:0040011]; muscle organ development [GO:0007517]; positive regulation of distal tip cell migration [GO:1903356]; positive regulation of myosin II filament organization [GO:1904901]; positive regulation of ovulation [GO:0060279]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of engulfment of apoptotic cell [GO:1901074] comp140469_c0_seq11,628,45.5414,0.61567229,0,0,,4.00E-10,Q54K81,Talin-B,Talin-B,GO:0015629; GO:0048102; GO:0005938; GO:0048870; GO:0031589; GO:0007010; GO:0030587; GO:0005198,actin cytoskeleton; autophagic cell death; cell cortex; cell motility; cell-substrate adhesion; cytoskeleton organization; sorocarp development; structural molecule activity,PF16511;PF00373;PF09379;PF01608;PF08913;PF02209;,,,,,,,,,TALB_DICDI,Dictyostelium discoideum (Slime mold),autophagic cell death [GO:0048102]; cell motility [GO:0048870]; cell-substrate adhesion [GO:0031589]; cytoskeleton organization [GO:0007010]; locomotion [GO:0040011]; sorocarp development [GO:0030587] comp140469_c0_seq2,2636,40.2883,0.54728932,0,0,,4.00E-168,Q96AC1,Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1),Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1),GO:0031674; GO:0016055; GO:0030036; GO:0005938; GO:0009986; GO:0005829; GO:0031234; GO:0031941; GO:0005925; GO:0048041; GO:0033622; GO:0007229; GO:0031258; GO:0005634; GO:0005547; GO:0072657; GO:0008360; GO:0001725; GO:0034446; GO:0007179,"I band; Wnt receptor signaling pathway; actin cytoskeleton organization; cell cortex; cell surface; cytosol; extrinsic to internal side of plasma membrane; filamentous actin; focal adhesion; focal adhesion assembly; integrin activation; integrin-mediated signaling pathway; lamellipodium membrane; nucleus; phosphatidylinositol-3,4,5-trisphosphate binding; protein localization to membrane; regulation of cell shape; stress fiber; substrate adhesion-dependent cell spreading; transforming growth factor beta receptor signaling pathway",PF00373;PF00169;,,,,,,,,,FERM2_HUMAN,Homo sapiens (Human),cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; protein localization to membrane [GO:0072657]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] comp140469_c0_seq3,1007,46.1768,0.504505,0,0,,1.00E-08,Q54K81,Talin-B,Talin-B,GO:0015629; GO:0048102; GO:0005938; GO:0048870; GO:0031589; GO:0007010; GO:0030587; GO:0005198,actin cytoskeleton; autophagic cell death; cell cortex; cell motility; cell-substrate adhesion; cytoskeleton organization; sorocarp development; structural molecule activity,PF16511;PF00373;PF09379;PF01608;PF08913;PF02209;,,,,,,,,,TALB_DICDI,Dictyostelium discoideum (Slime mold),autophagic cell death [GO:0048102]; cell motility [GO:0048870]; cell-substrate adhesion [GO:0031589]; cytoskeleton organization [GO:0007010]; locomotion [GO:0040011]; sorocarp development [GO:0030587] comp140469_c0_seq4,2319,40.4916,0.52385175,0,0,,1.00E-148,Q32LP0,Fermitin family homolog 3 (Kindlin-3) (Unc-112-related protein 2),Fermitin family homolog 3 (Kindlin-3) (Unc-112-related protein 2),GO:0030054; GO:0042995; GO:0033622; GO:0005178; GO:0007159; GO:0005543; GO:0070527; GO:0002102; GO:0033632,cell junction; cell projection; integrin activation; integrin binding; leukocyte cell-cell adhesion; phospholipid binding; platelet aggregation; podosome; regulation of cell-cell adhesion mediated by integrin,PF00373;PF00169;,,,,,,,,,URP2_BOVIN,Bos taurus (Bovine),integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; substrate adhesion-dependent cell spreading [GO:0034446] comp140469_c0_seq5,1847,43.2052,0.62810872,0,0,,,,,,,,,4.00E-62,CHOYP_LOC100366451.1.1,,,,,,,,, comp140469_c0_seq6,1831,37.8482,0.46937465,0,0,,3.00E-09,Q71LX4,Talin-2,Talin-2,GO:0015629; GO:0007155; GO:0005737; GO:0007016; GO:0005916; GO:0005925; GO:0005886; GO:0001726; GO:0005200; GO:0045202,actin cytoskeleton; cell adhesion; cytoplasm; cytoskeletal anchoring at plasma membrane; fascia adherens; focal adhesion; plasma membrane; ruffle; structural constituent of cytoskeleton; synapse,PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;,,,,,,,,,TLN2_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016] comp140469_c0_seq7,3159,40.2343,0.59313768,0,0,,0,Q9VZI3,Unc-112-related protein (Fermitin-1),Unc-112-related protein (Fermitin-1),GO:0048738; GO:0050839; GO:0007160; GO:0005737; GO:0050829; GO:0005543,cardiac muscle tissue development; cell adhesion molecule binding; cell-matrix adhesion; cytoplasm; defense response to Gram-negative bacterium; phospholipid binding,PF00373;PF00169;,,,,,,,,,UN112_DROME,Drosophila melanogaster (Fruit fly),cardiac muscle tissue development [GO:0048738]; cell-matrix adhesion [GO:0007160]; defense response to Gram-negative bacterium [GO:0050829] comp140469_c0_seq8,1468,42.1662,0.72176955,0,0,,3.00E-93,Q9VZI3,Unc-112-related protein (Fermitin-1),Unc-112-related protein (Fermitin-1),GO:0048738; GO:0050839; GO:0007160; GO:0005737; GO:0050829; GO:0005543,cardiac muscle tissue development; cell adhesion molecule binding; cell-matrix adhesion; cytoplasm; defense response to Gram-negative bacterium; phospholipid binding,PF00373;PF00169;,3.00E-62,CHOYP_LOC100366451.1.1,2.00E-95,ruditapes_c1597,,,,,UN112_DROME,Drosophila melanogaster (Fruit fly),cardiac muscle tissue development [GO:0048738]; cell-matrix adhesion [GO:0007160]; defense response to Gram-negative bacterium [GO:0050829] comp140469_c0_seq9,519,42.1965,0.34817672,0,0,,2.00E-53,Q8CIB5,Fermitin family homolog 2 (Kindlin-2) (Pleckstrin homology domain-containing family C member 1),Fermitin family homolog 2 (Kindlin-2) (Pleckstrin homology domain-containing family C member 1),GO:0031674; GO:0016055; GO:0005938; GO:0009986; GO:0005737; GO:0005856; GO:0031234; GO:0005925; GO:0048041; GO:0033622; GO:0007229; GO:0031258; GO:0005634; GO:0005547; GO:0072657; GO:0008360; GO:0034446; GO:0007179,"I band; Wnt receptor signaling pathway; cell cortex; cell surface; cytoplasm; cytoskeleton; extrinsic to internal side of plasma membrane; focal adhesion; focal adhesion assembly; integrin activation; integrin-mediated signaling pathway; lamellipodium membrane; nucleus; phosphatidylinositol-3,4,5-trisphosphate binding; protein localization to membrane; regulation of cell shape; substrate adhesion-dependent cell spreading; transforming growth factor beta receptor signaling pathway",PF00373;PF00169;,,,,,,,,,FERM2_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; protein localization to membrane [GO:0072657]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] comp140471_c0_seq2,1702,35.7227,0.73969534,111,336,,2.00E-60,Q9H300,"Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]","Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]",GO:0016021; GO:0005743; GO:0005739; GO:2001243; GO:0090201; GO:0005634; GO:0006508; GO:0004252,integral to membrane; mitochondrial inner membrane; mitochondrion; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of release of cytochrome c from mitochondria; nucleus; proteolysis; serine-type endopeptidase activity,PF01694;,,,,,,,,,PARL_HUMAN,Homo sapiens (Human),membrane protein proteolysis [GO:0033619]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of mitophagy [GO:1903146]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of proteolysis [GO:0030162]; regulation of reactive oxygen species metabolic process [GO:2000377] comp140473_c0_seq1,1257,41.6866,0.45033141,330,2568,,3.00E-152,Q6GR45,Eukaryotic translation initiation factor 6 (eIF-6),Eukaryotic translation initiation factor 6 (eIF-6),GO:0005737; GO:0042256; GO:0005730; GO:0043022; GO:0003743,cytoplasm; mature ribosome assembly; nucleolus; ribosome binding; translation initiation factor activity,PF01912;,1.00E-131,CHOYP_IF6.1.1,,,,,,,IF6_XENLA,Xenopus laevis (African clawed frog),mature ribosome assembly [GO:0042256]; ribosomal large subunit biogenesis [GO:0042273] comp140474_c0_seq1,809,39.9258,0.40372732,0,0,,7.00E-62,Q8N6W0,CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5),CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus,PF00076;,,,,,,,,,CELF5_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397] comp140474_c0_seq11,816,40.1961,0.45647627,0,0,,8.00E-62,Q8N6W0,CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5),CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus,PF00076;,,,,,,,,,CELF5_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397] comp140474_c0_seq12,706,40.085,0.35385456,0,0,,1.00E-90,A4IIM2,CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (RNA-binding protein BRUNOL-3),CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (RNA-binding protein BRUNOL-3),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus,PF00076;,5.00E-120,CHOYP_CELF2.3.4,,,,,,,CELF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397] comp140474_c0_seq13,1245,41.5261,0.85812728,63,76,,2.00E-29,Q0V9L3,CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0048026,"RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome",PF00076;,2.00E-19,CHOYP_CELF4.1.1,,,,,,,CELF4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]" comp140474_c0_seq14,722,40.5817,0.37108134,0,0,,3.00E-08,Q00916,U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1),U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1),GO:0030619; GO:0005685; GO:0071004; GO:0000243; GO:0003729; GO:0000398; GO:0000166,"U1 snRNA binding; U1 snRNP; U2-type prespliceosome; commitment complex; mRNA binding; mRNA splicing, via spliceosome; nucleotide binding",PF00076;PF12220;,,,,,,,,,RU17_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"mRNA splicing, via spliceosome [GO:0000398]" comp140474_c0_seq3,713,40.3927,0.41321518,0,0,,2.00E-90,A4IIM2,CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (RNA-binding protein BRUNOL-3),CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (RNA-binding protein BRUNOL-3),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus,PF00076;,2.00E-117,CHOYP_CELF2.4.4,,,,,,,CELF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397] comp140474_c0_seq4,729,40.8779,0.42753606,0,0,,2.00E-08,B0BN49,"RNA-binding motif protein, X-linked 2","RNA-binding motif protein, X-linked 2",GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,3.00E-103,CHOYP_CELF2.1.4,,,,,,,RBMX2_RAT,Rattus norvegicus (Rat),"mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]" comp140474_c0_seq6,1286,42.0684,0.89963048,1,0,,3.00E-30,Q0V9L3,CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0048026,"RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome",PF00076;,9.00E-88,CHOYP_CELF2.4.4,,,,,,,CELF4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]" comp140474_c0_seq9,825,40.3636,0.41714223,0,0,,4.00E-06,Q9V535,RNA-binding protein 8A (Protein tsunagi),RNA-binding protein 8A (Protein tsunagi),GO:0071013; GO:0005737; GO:0007173; GO:0046595; GO:0035145; GO:0007294; GO:0003729; GO:0006406; GO:0000398; GO:0000226; GO:0000166; GO:0007312; GO:0045451; GO:0007317,"catalytic step 2 spliceosome; cytoplasm; epidermal growth factor receptor signaling pathway; establishment of pole plasm mRNA localization; exon-exon junction complex; germarium-derived oocyte fate determination; mRNA binding; mRNA export from nucleus; mRNA splicing, via spliceosome; microtubule cytoskeleton organization; nucleotide binding; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; pole plasm oskar mRNA localization; regulation of pole plasm oskar mRNA localization",PF00076;,,,,,,,,,RBM8A_DROME,Drosophila melanogaster (Fruit fly),"epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of pole plasm mRNA localization [GO:0046595]; germarium-derived oocyte fate determination [GO:0007294]; microtubule cytoskeleton organization [GO:0000226]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transposition, DNA-mediated [GO:0000335]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification [GO:0007312]; pole plasm oskar mRNA localization [GO:0045451]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA splicing [GO:0008380]" comp140476_c0_seq2,2789,46.54,0.59304858,0,3,,3.00E-105,Q08379,Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95),Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95),GO:0032580; GO:0051645; GO:0000139; GO:0005801; GO:0000278; GO:0050772,Golgi cisterna membrane; Golgi localization; Golgi membrane; cis-Golgi network; mitotic cell cycle; positive regulation of axonogenesis,PF15070;,2.00E-67,CHOYP_LOC100492442.1.1,,,,,,,GOGA2_HUMAN,Homo sapiens (Human),asymmetric cell division [GO:0008356]; centrosome organization [GO:0051297]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi ribbon formation [GO:0090161]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; negative regulation of autophagy [GO:0010507]; negative regulation of protein binding [GO:0032091]; positive regulation of protein glycosylation [GO:0060050]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; spindle assembly [GO:0051225]; spindle assembly involved in meiosis [GO:0090306] comp140476_c0_seq3,2867,46.39,0.58700331,0,6,,3.00E-117,Q62839,Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130),Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130),GO:0000137; GO:0032580; GO:0000139; GO:0005801; GO:0043025; GO:0043234; GO:0032403,Golgi cis cisterna; Golgi cisterna membrane; Golgi membrane; cis-Golgi network; neuronal cell body; protein complex; protein complex binding,PF15070;,,,,,,,,,GOGA2_RAT,Rattus norvegicus (Rat),asymmetric cell division [GO:0008356]; centrosome organization [GO:0051297]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi ribbon formation [GO:0090161]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; spindle assembly [GO:0051225]; spindle assembly involved in meiosis [GO:0090306] comp140477_c1_seq1,1414,45.1909,0.38634636,26,712,,0,Q28811,Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) (DNA photolyase) (Photoreactivating enzyme),Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) (DNA photolyase) (Photoreactivating enzyme),GO:0003677; GO:0006281; GO:0003904; GO:0018298,DNA binding; DNA repair; deoxyribodipyrimidine photo-lyase activity; protein-chromophore linkage,PF00875;,3.00E-132,CHOYP_PHR.1.1,,,,,,,PHR_POTTR,Potorous tridactylus (Potoroo),DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298] comp140477_c4_seq1,653,41.1945,0.47715905,5,184,,,,,,,,,2.00E-41,CHOYP_PHR.1.1,,,,,,,,, comp140478_c0_seq1,1255,36.9721,0.91689187,0,0,,8.00E-24,Q99J87,Probable ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor Lgp2) (RLR),Probable ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor Lgp2) (RLR),GO:0005524; GO:0003677; GO:0005737; GO:0051607; GO:0003725; GO:0004386; GO:0045087; GO:0039534; GO:0039536; GO:0045824; GO:0032480; GO:1900245; GO:1900246; GO:0032481; GO:0009615; GO:0003727; GO:0008270,ATP binding; DNA binding; cytoplasm; defense response to virus; double-stranded RNA binding; helicase activity; innate immune response; negative regulation of MDA-5 signaling pathway; negative regulation of RIG-I signaling pathway; negative regulation of innate immune response; negative regulation of type I interferon production; positive regulation of MDA-5 signaling pathway; positive regulation of RIG-I signaling pathway; positive regulation of type I interferon production; response to virus; single-stranded RNA binding; zinc ion binding,PF00271;PF04851;PF11648;,,,,,,,,,DHX58_MOUSE,Mus musculus (Mouse),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of innate immune response [GO:0045088]; response to virus [GO:0009615] comp140478_c0_seq4,2297,37.1354,0.9650274,0,0,,2.00E-10,Q09884,Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)],Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)],GO:0005524; GO:0016442; GO:0007049; GO:0034613; GO:0031048; GO:0007059; GO:0033562; GO:0005829; GO:0003690; GO:0003725; GO:0035389; GO:1990188; GO:0004386; GO:0031618; GO:0005719; GO:0034399; GO:0005643; GO:0030422; GO:0090052; GO:0051570; GO:0004525; GO:0004540; GO:0008270,ATP binding; RISC complex; cell cycle; cellular protein localization; chromatin silencing by small RNA; chromosome segregation; co-transcriptional gene silencing by RNA interference machinery; cytosol; double-stranded DNA binding; double-stranded RNA binding; establishment of chromatin silencing at silent mating-type cassette; euchromatin binding; helicase activity; nuclear centromeric heterochromatin; nuclear euchromatin; nuclear periphery; nuclear pore; production of siRNA involved in RNA interference; regulation of chromatin silencing at centromere; regulation of histone H3-K9 methylation; ribonuclease III activity; ribonuclease activity; zinc ion binding,PF03368;PF00271;PF04851;PF00636;,,,,,,,,,DCR1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell cycle [GO:0007049]; cellular protein localization [GO:0034613]; chromatin silencing at centromere outer repeat region [GO:1990141]; chromatin silencing by small RNA [GO:0031048]; chromosome segregation [GO:0007059]; co-transcriptional gene silencing by RNA interference machinery [GO:0033562]; establishment of chromatin silencing at silent mating-type cassette [GO:0035389]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of gene expression [GO:0010629]; positive regulation of termination of RNA polymerase II transcription [GO:1904595]; production of siRNA involved in RNA interference [GO:0030422]; regulation of chromatin silencing at centromere [GO:0090052]; regulation of histone H3-K9 methylation [GO:0051570]; RNA processing [GO:0006396] comp140478_c0_seq5,2724,36.1968,0.93773094,0,0,,4.00E-62,Q9GLV6,Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RHIV-1) (RIG-I-like receptor 1) (RLR-1) (RNA helicase induced by virus) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RHIV-1) (RIG-I-like receptor 1) (RLR-1) (RNA helicase induced by virus) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I),GO:0005524; GO:0008026; GO:0039529; GO:0015629; GO:0005737; GO:0003725; GO:0045087; GO:0002230; GO:0032727; GO:0032728; GO:0030334; GO:0032587; GO:0003727; GO:0005923; GO:0008270,ATP binding; ATP-dependent helicase activity; RIG-I signaling pathway; actin cytoskeleton; cytoplasm; double-stranded RNA binding; innate immune response; positive regulation of defense response to virus by host; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; regulation of cell migration; ruffle membrane; single-stranded RNA binding; tight junction; zinc ion binding,PF16739;PF00270;PF00271;PF11648;,,,,,,,,,DDX58_PIG,Sus scrofa (Pig),innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; regulation of cell migration [GO:0030334]; RIG-I signaling pathway [GO:0039529] comp140479_c0_seq1,1584,42.803,0.4656786,369,802,,0,Q8MKI8,DNA repair protein RAD51 homolog 1 (cRad51),DNA repair protein RAD51 homolog 1 (cRad51),GO:0005524; GO:0006268; GO:0016605; GO:0072757; GO:0071479; GO:0000794; GO:0003684; GO:0000724; GO:0003690; GO:0000800; GO:0007126; GO:0005759; GO:0048471; GO:0051106; GO:0051260; GO:0010569; GO:0003697; GO:0043142,ATP binding; DNA unwinding involved in DNA replication; PML body; cellular response to camptothecin; cellular response to ionizing radiation; condensed nuclear chromosome; damaged DNA binding; double-strand break repair via homologous recombination; double-stranded DNA binding; lateral element; meiosis; mitochondrial matrix; perinuclear region of cytoplasm; positive regulation of DNA ligation; protein homooligomerization; regulation of double-strand break repair via homologous recombination; single-stranded DNA binding; single-stranded DNA-dependent ATPase activity,PF08423;,0,CHOYP_RAD51.1.1,,,9.00E-110,AM864373.p.cg.6,8,,RAD51_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; homologous recombination-dependent replication fork processing [GO:1990426]; meiotic nuclear division [GO:0007126]; mitotic recombination [GO:0006312]; positive regulation of DNA ligation [GO:0051106]; protein homooligomerization [GO:0051260]; reciprocal meiotic recombination [GO:0007131]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein phosphorylation [GO:0001932]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to ionizing radiation [GO:0010212]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomere lengthening [GO:0010833] comp140484_c0_seq1,2529,39.3436,0.38897256,1,27,,,,,,,,,3.00E-60,CHOYP_LOC100692988.1.1,,,,,,,,, comp140484_c0_seq2,2502,39.3685,0.39281237,3,11,,4.00E-157,Q15022,Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog),Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog),GO:0035098; GO:0003682; GO:0042054; GO:0016574; GO:0046872; GO:0035064; GO:0045596; GO:0000122; GO:0008284; GO:0043565; GO:0001739; GO:0006351,"ESC/E(Z) complex; chromatin binding; histone methyltransferase activity; histone ubiquitination; metal ion binding; methylated histone residue binding; negative regulation of cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell proliferation; sequence-specific DNA binding; sex chromatin; transcription, DNA-dependent",PF09733;,,,,,,,,,SUZ12_HUMAN,Homo sapiens (Human),"histone ubiquitination [GO:0016574]; negative regulation of cell differentiation [GO:0045596]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]" comp140484_c0_seq3,1433,38.5904,0.46910598,0,0,,9.00E-06,Q8L6Y4,Polycomb group protein EMBRYONIC FLOWER 2,Polycomb group protein EMBRYONIC FLOWER 2,GO:0003677; GO:0030154; GO:0009908; GO:0046872; GO:0009910; GO:0005634; GO:0006349; GO:0003700; GO:0006351,"DNA binding; cell differentiation; flower development; metal ion binding; negative regulation of flower development; nucleus; regulation of gene expression by genetic imprinting; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF09733;,1.00E-60,CHOYP_LOC100692988.1.1,,,,,,,EMF2_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell differentiation [GO:0030154]; flower development [GO:0009908]; negative regulation of flower development [GO:0009910]; regulation of gene expression by genetic imprinting [GO:0006349]; transcription, DNA-templated [GO:0006351]" comp140491_c1_seq1,2589,44.0324,0.653968,5,0,,9.00E-26,Q29000,Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) (Fragments),Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) (Fragments),GO:0005524; GO:0051389; GO:0016021; GO:0043066; GO:0018108; GO:0046328; GO:0004714,ATP binding; inactivation of MAPKK activity; integral to membrane; negative regulation of apoptotic process; peptidyl-tyrosine phosphorylation; regulation of JNK cascade; transmembrane receptor protein tyrosine kinase activity,PF00041;,,,,,,,,,IGF1R_PIG,Sus scrofa (Pig),inactivation of MAPKK activity [GO:0051389]; negative regulation of apoptotic process [GO:0043066]; regulation of JNK cascade [GO:0046328] comp140491_c1_seq10,961,43.8085,0.68559548,0,0,,4.00E-22,P22455,Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334),Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334),GO:0005524; GO:0038095; GO:0061144; GO:0016477; GO:0005783; GO:0005768; GO:0007173; GO:0005576; GO:0017134; GO:0005007; GO:0042593; GO:0008201; GO:0045087; GO:0008286; GO:0005887; GO:0048011; GO:0005634; GO:0001759; GO:0055062; GO:0048015; GO:2000573; GO:0070374; GO:0008284; GO:0048554; GO:0045862; GO:0046777; GO:0070857; GO:2000188; GO:0010715,ATP binding; Fc-epsilon receptor signaling pathway; alveolar secondary septum development; cell migration; endoplasmic reticulum; endosome; epidermal growth factor receptor signaling pathway; extracellular region; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; glucose homeostasis; heparin binding; innate immune response; insulin receptor signaling pathway; integral to plasma membrane; neurotrophin TRK receptor signaling pathway; nucleus; organ induction; phosphate ion homeostasis; phosphatidylinositol-mediated signaling; positive regulation of DNA biosynthetic process; positive regulation of ERK1 and ERK2 cascade; positive regulation of cell proliferation; positive regulation of metalloenzyme activity; positive regulation of proteolysis; protein autophosphorylation; regulation of bile acid biosynthetic process; regulation of cholesterol homeostasis; regulation of extracellular matrix disassembly,PF07679;PF07714;,,,2.00E-53,ruditapes_c8584,,,,,FGFR4_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glucose homeostasis [GO:0042593]; MAPK cascade [GO:0000165]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphate ion homeostasis [GO:0055062]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of proteolysis [GO:0045862]; protein autophosphorylation [GO:0046777]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of cholesterol homeostasis [GO:2000188]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of lipid metabolic process [GO:0019216]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp140491_c1_seq2,1424,43.75,0.66026443,71,79,,1.00E-119,Q25410,Putative molluscan insulin-related peptide(s) receptor (EC 2.7.10.1) [Cleaved into: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain],Putative molluscan insulin-related peptide(s) receptor (EC 2.7.10.1) [Cleaved into: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain],GO:0005524; GO:0016021; GO:0046872; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; metal ion binding; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF00757;PF07714;PF01030;,2.00E-104,CHOYP_MIPR.1.2,,,1.00E-101,AJ535669.p.cg.6,2,,MIPR_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp140491_c1_seq5,1736,43.03,0.58551981,0,0,,2.00E-103,O02466,Insulin-like peptide receptor (ILP receptor) (EC 2.7.10.1) [Cleaved into: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain],Insulin-like peptide receptor (ILP receptor) (EC 2.7.10.1) [Cleaved into: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain],GO:0005524; GO:0016021; GO:0046872; GO:0018108; GO:0046777; GO:0004714; GO:0007169,ATP binding; integral to membrane; metal ion binding; peptidyl-tyrosine phosphorylation; protein autophosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF00757;PF07714;PF01030;,,,,,,,,,ILPR_BRALA,Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum),protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp140491_c1_seq6,2701,43.9097,0.68463692,0,0,,5.00E-121,Q25410,Putative molluscan insulin-related peptide(s) receptor (EC 2.7.10.1) [Cleaved into: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain],Putative molluscan insulin-related peptide(s) receptor (EC 2.7.10.1) [Cleaved into: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain],GO:0005524; GO:0016021; GO:0046872; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; metal ion binding; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF00757;PF07714;PF01030;,,,,,,,,,MIPR_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp140491_c1_seq7,1624,43.165,0.56878328,0,0,,7.00E-55,Q968Y9,Insulin-like receptor (IR) (EC 2.7.10.1) (Abnormal dauer formation protein 2) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta],Insulin-like receptor (IR) (EC 2.7.10.1) (Abnormal dauer formation protein 2) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta],GO:0005524; GO:0042169; GO:0005975; GO:0043054; GO:0008340; GO:0045087; GO:0005009; GO:0016021; GO:0046872; GO:0042992; GO:0017046; GO:0040018; GO:0046777; GO:2000785; GO:0040034; GO:1901031; GO:0000003,"ATP binding; SH2 domain binding; carbohydrate metabolic process; dauer exit; determination of adult lifespan; innate immune response; insulin-activated receptor activity; integral to membrane; metal ion binding; negative regulation of transcription factor import into nucleus; peptide hormone binding; positive regulation of multicellular organism growth; protein autophosphorylation; regulation of autophagic vacuole assembly; regulation of development, heterochronic; regulation of response to reactive oxygen species; reproduction",PF00757;PF07714;PF01030;,,,,,,,,,INSR_CAEEL,Caenorhabditis elegans,"carbohydrate metabolic process [GO:0005975]; dauer entry [GO:0043053]; dauer exit [GO:0043054]; dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; innate immune response [GO:0045087]; insulin receptor signaling pathway [GO:0008286]; larval feeding behavior [GO:0030536]; negative regulation of transcription factor import into nucleus [GO:0042992]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; protein autophosphorylation [GO:0046777]; regulation of autophagosome assembly [GO:2000785]; regulation of dauer larval development [GO:0061065]; regulation of development, heterochronic [GO:0040034]; regulation of eating behavior [GO:1903998]; regulation of response to reactive oxygen species [GO:1901031]; reproduction [GO:0000003]" comp140491_c1_seq9,1253,43.735,0.75566495,3,0,,7.00E-46,Q05688,Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment),Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment),GO:0005524; GO:0006955; GO:0051389; GO:0043559; GO:0043560; GO:0005520; GO:0005010; GO:0016021; GO:0043231; GO:0043066; GO:0043548; GO:0048015; GO:0045740; GO:0030335; GO:0046777; GO:0051262; GO:0046328,ATP binding; immune response; inactivation of MAPKK activity; insulin binding; insulin receptor substrate binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; integral to membrane; intracellular membrane-bounded organelle; negative regulation of apoptotic process; phosphatidylinositol 3-kinase binding; phosphatidylinositol-mediated signaling; positive regulation of DNA replication; positive regulation of cell migration; protein autophosphorylation; protein tetramerization; regulation of JNK cascade,PF00041;PF07714;,,,,,,,,,IGF1R_BOVIN,Bos taurus (Bovine),inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328] comp140492_c0_seq1,2307,41.9159,0.85699252,236,565,,3.00E-71,Q8CN04,1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase),1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase),GO:0003842; GO:0006537; GO:0016620; GO:0006561; GO:0010133,"1-pyrroline-5-carboxylate dehydrogenase activity; glutamate biosynthetic process; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; proline biosynthetic process; proline catabolic process to glutamate",PF00171;,,,,,,,,,ROCA_STAES,Staphylococcus epidermidis (strain ATCC 12228),glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133] comp140492_c0_seq2,2331,41.8704,0.86979905,495,1594,,0,P20000,"Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI)","Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI)",GO:0004029; GO:0006068; GO:0005759,aldehyde dehydrogenase (NAD) activity; ethanol catabolic process; mitochondrial matrix,PF00171;,7.00E-105,CHOYP_ALDH2.3.3,2.00E-33,ruditapes2_c1038,,,,,ALDH2_BOVIN,Bos taurus (Bovine),ethanol catabolic process [GO:0006068] comp140493_c0_seq3,1219,40.1969,0.38310593,48,211,,4.00E-23,Q9WYX8,Uncharacterized protein TM_0508,Uncharacterized protein TM_0508,GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009378,ATP binding; DNA binding; DNA recombination; DNA repair; DNA replication; four-way junction helicase activity,PF16193;PF01661;PF12002;PF05496;,,,,,,,,,Y508_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp140497_c0_seq1,1879,37.4667,0.50162127,116,603,,5.00E-116,B8A5G9,tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog),tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog),GO:0005759; GO:0005634; GO:0052906,mitochondrial matrix; nucleus; tRNA (guanine(37)-N(1))-methyltransferase activity,PF02475;,,,,,,,,,TRM5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140498_c0_seq1,2312,40.5709,0.4495066,45,210,,0,P55096,ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70),ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70),GO:0005524; GO:0042626; GO:0006635; GO:0016021; GO:0005743; GO:0005782; GO:0005778; GO:0007031; GO:0042760,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; fatty acid beta-oxidation; integral to membrane; mitochondrial inner membrane; peroxisomal matrix; peroxisomal membrane; peroxisome organization; very long-chain fatty acid catabolic process",PF06472;PF00005;,0,CHOYP_ABCD3.1.1,,,,,,,ABCD3_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation [GO:0006635]; fatty acid biosynthetic process [GO:0006633]; peroxisomal long-chain fatty acid import [GO:0015910]; peroxisome organization [GO:0007031]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; very long-chain fatty acid catabolic process [GO:0042760] comp140498_c0_seq3,2302,40.5734,0.46276756,28,117,,0,P55096,ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70),ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70),GO:0005524; GO:0042626; GO:0006635; GO:0016021; GO:0005743; GO:0005782; GO:0005778; GO:0007031; GO:0042760,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; fatty acid beta-oxidation; integral to membrane; mitochondrial inner membrane; peroxisomal matrix; peroxisomal membrane; peroxisome organization; very long-chain fatty acid catabolic process",PF06472;PF00005;,,,,,,,,,ABCD3_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation [GO:0006635]; fatty acid biosynthetic process [GO:0006633]; peroxisomal long-chain fatty acid import [GO:0015910]; peroxisome organization [GO:0007031]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; very long-chain fatty acid catabolic process [GO:0042760] comp140500_c0_seq2,1672,43.6005,0.31893894,80,279,,2.00E-147,Q9H1I8,Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100),Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100),GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02845;,2.00E-40,CHOYP_ASCC2.1.1,,,,,,,ASCC2_HUMAN,Homo sapiens (Human),"DNA dealkylation involved in DNA repair [GO:0006307]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140500_c0_seq3,1067,38.3318,0.67909084,0,0,,1.00E-11,Q91WR3,Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100),Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100),GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02845;,,,4.00E-19,ruditapes_c19769,,,,,ASCC2_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140502_c0_seq1,2016,39.3353,1.00241978,2,2317,female>male,8.00E-48,O54750,Cytochrome P450 2J6 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ6),Cytochrome P450 2J6 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ6),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2J6_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; epoxygenase P450 pathway [GO:0019373]; linoleic acid metabolic process [GO:0043651] comp140504_c0_seq2,1406,36.6287,0.77752029,92,197,,9.00E-98,Q9BXY0,Protein MAK16 homolog (NNP78) (Protein RBM13),Protein MAK16 homolog (NNP78) (Protein RBM13),GO:0005730,nucleolus,PF04874;PF01778;,3.00E-95,CHOYP_LOC100377801.1.1,,,,,,,MAK16_HUMAN,Homo sapiens (Human),maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] comp140505_c0_seq6,1286,41.2131,0.55474171,5,17,,3.00E-08,P46012,Uncharacterized protein C01G6.5,Uncharacterized protein C01G6.5,,,PF00498;,,,,,,,,,YKI5_CAEEL,Caenorhabditis elegans, comp140505_c0_seq7,640,37.3438,0.6820133,0,0,,9.00E-06,Q3UXZ9,Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2),Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2),GO:0003677; GO:0003682; GO:0016568; GO:0019907; GO:0005737; GO:0007275; GO:0005730; GO:0016706; GO:0045893; GO:0006351; GO:0008270,"DNA binding; chromatin binding; chromatin modification; cyclin-dependent protein kinase activating kinase holoenzyme complex; cytoplasm; multicellular organismal development; nucleolus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;,,,,,,,,,KDM5A_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; histone H3-K4 demethylation [GO:0034720]; male gonad development [GO:0008584]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp140507_c0_seq1,3524,40.2951,0.45860683,2036,5953,,1.00E-143,O75400,Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6),Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6),GO:0008380; GO:0007049; GO:0051301; GO:0016477; GO:0007010; GO:0006397; GO:0016363; GO:0016607; GO:0008360; GO:0032465,RNA splicing; cell cycle; cell division; cell migration; cytoskeleton organization; mRNA processing; nuclear matrix; nuclear speck; regulation of cell shape; regulation of cytokinesis,PF01846;PF00397;,1.00E-172,CHOYP_BRAFLDRAFT_57552.1.1,1.00E-63,ruditapes_c28437,,,,,PR40A_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; mRNA splicing, via spliceosome [GO:0000398]; regulation of cell shape [GO:0008360]; regulation of cytokinesis [GO:0032465]" comp140508_c0_seq2,1448,37.3619,0.4602393,2,0,,2.00E-130,Q6DRC3,Uncharacterized protein C21orf59 homolog,UPF0769 protein C21orf59 homolog,,,PF11069;,7.00E-128,CHOYP_CYTB.1.6,,,,,,,CU059_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium morphogenesis [GO:0060271] comp140510_c0_seq2,1960,33.5714,0.41873711,18,166,,1.00E-30,Q54UU1,Trafficking protein particle complex subunit 4,Trafficking protein particle complex subunit 4,GO:0006888; GO:0005794; GO:0005801; GO:0005783,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network; endoplasmic reticulum,PF04099;,2.00E-79,CHOYP_BRAFLDRAFT_114158.1.1,,,,,,,TPPC4_DICDI,Dictyostelium discoideum (Slime mold),ER to Golgi vesicle-mediated transport [GO:0006888] comp140510_c0_seq3,2279,35.8052,0.51144951,0,0,,4.00E-104,Q9ES56,Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog),Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog),GO:0006888; GO:0005795; GO:0030008; GO:0030054; GO:0005801; GO:0030425; GO:0016358; GO:0005783; GO:0045212; GO:0005886; GO:0045211; GO:0008021; GO:0016192,ER to Golgi vesicle-mediated transport; Golgi stack; TRAPP complex; cell junction; cis-Golgi network; dendrite; dendrite development; endoplasmic reticulum; neurotransmitter receptor biosynthetic process; plasma membrane; postsynaptic membrane; synaptic vesicle; vesicle-mediated transport,PF04099;,,,1.00E-42,ruditapes_c22773,,,,,TPPC4_MOUSE,Mus musculus (Mouse),dendrite development [GO:0016358]; ER to Golgi vesicle-mediated transport [GO:0006888]; neurotransmitter receptor biosynthetic process [GO:0045212]; vesicle-mediated transport [GO:0016192] comp140513_c0_seq2,1235,44.6964,0.73019005,48,94,,2.00E-91,Q9NQV6,PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin),PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;PF12171;,1.00E-54,CHOYP_BRAFLDRAFT_125682.1.1,,,,,,,PRD10_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140513_c0_seq5,674,44.9555,0.51573147,32,9,,1.00E-07,Q9NQV5,PR domain-containing protein 11 (EC 2.1.1.-),PR domain-containing protein 11 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF00856;,,,,,,,,,PRD11_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140515_c2_seq1,3003,44.5221,0.42653149,2408,84,,1.00E-73,Q5W041,Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1),Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1),,,PF00514;,0,CHOYP_LOC100370900.1.1,,,,,,,ARMC3_HUMAN,Homo sapiens (Human), comp140516_c1_seq1,1441,39.4171,0.48445281,0,0,,1.00E-87,Q71B07,Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3),Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF10034;,1.00E-79,CHOYP_DPY19L3.1.1,,,,,,,D19L3_MOUSE,Mus musculus (Mouse),protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] comp140516_c1_seq7,1489,39.221,0.49161033,0,0,,3.00E-69,Q5RCJ4,Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3),Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF10034;,1.00E-79,CHOYP_DPY19L3.1.1,,,,,,,D19L3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140519_c0_seq3,326,40.7975,0.59726589,8,140,,6.00E-12,Q5RAS8,Transmembrane protein 199,Transmembrane protein 199,GO:0016021,integral to membrane,PF11712;,,,,,,,,,TM199_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140521_c1_seq5,883,39.1846,0.44687147,0,1,,2.00E-15,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140521_c1_seq9,478,41.841,0.62370065,0,0,,2.00E-23,Q17QR8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_BOVIN,Bos taurus (Bovine), comp140525_c0_seq1,2507,41.7232,0.522911,564,1006,,9.00E-121,Q9H0H5,Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4),Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4),GO:0005096; GO:0001669; GO:0043014; GO:0019886; GO:0048487; GO:0007596; GO:0097149; GO:0032154; GO:0000915; GO:0007108; GO:0005829; GO:0009790; GO:0043015; GO:0046872; GO:0005874; GO:0008017; GO:0007018; GO:0030496; GO:0007405; GO:0005634; GO:0032467; GO:0051988; GO:0051056; GO:0007264; GO:0007283; GO:0051233; GO:0051256; GO:0008272,"GTPase activator activity; acrosomal vesicle; alpha-tubulin binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; beta-tubulin binding; blood coagulation; centralspindlin complex; cleavage furrow; cytokinesis, actomyosin contractile ring assembly; cytokinesis, initiation of separation; cytosol; embryo development; gamma-tubulin binding; metal ion binding; microtubule; microtubule binding; microtubule-based movement; midbody; neuroblast proliferation; nucleus; positive regulation of cytokinesis; regulation of attachment of spindle microtubules to kinetochore; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; spermatogenesis; spindle midzone; spindle midzone assembly involved in mitosis; sulfate transport",PF00130;PF00620;,7.00E-112,CHOYP_CPIPJ_CPIJ007723.2.4,,,,,,,RGAP1_HUMAN,Homo sapiens (Human),"actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; embryo development [GO:0009790]; intracellular signal transduction [GO:0035556]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; neuroblast proliferation [GO:0007405]; positive regulation of cytokinesis [GO:0032467]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of small GTPase mediated signal transduction [GO:0051056]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; spermatogenesis [GO:0007283]; sulfate transport [GO:0008272]" comp140529_c0_seq1,1602,38.9513,0.42253612,1217,6766,,4.00E-118,Q8BH95,"Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH)","Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH)",GO:0004300; GO:0006635; GO:0005759; GO:0005739,enoyl-CoA hydratase activity; fatty acid beta-oxidation; mitochondrial matrix; mitochondrion,PF00378;,3.00E-114,CHOYP_ECHM.1.1,7.00E-69,ruditapes_c13636,,,,,ECHM_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation [GO:0006635] comp140533_c1_seq1,386,37.8238,0.50988485,23,171,,6.00E-10,Q8TBK6,Zinc finger CCHC domain-containing protein 10,Zinc finger CCHC domain-containing protein 10,GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,,,,,,,,,,ZCH10_HUMAN,Homo sapiens (Human), comp140534_c0_seq1,919,43.9608,0.41563185,0,0,,8.00E-16,P23678,Kinesin-like protein unc-104 (Uncoordinated protein 104),Kinesin-like protein unc-104 (Uncoordinated protein 104),GO:0005524; GO:0008089; GO:0030424; GO:0007049; GO:0051301; GO:0005737; GO:0030421; GO:0030425; GO:0007631; GO:0005871; GO:0005874; GO:0008017; GO:0018996; GO:0002119; GO:0007270; GO:0005546; GO:0070273; GO:0008574; GO:0040010; GO:0040018; GO:0010940; GO:0045887; GO:0043113; GO:0045055; GO:0030516; GO:0006942; GO:0000003; GO:0045202; GO:0007271,"ATP binding; anterograde axon cargo transport; axon; cell cycle; cell division; cytoplasm; defecation; dendrite; feeding behavior; kinesin complex; microtubule; microtubule binding; molting cycle, collagen and cuticulin-based cuticle; nematode larval development; neuron-neuron synaptic transmission; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; plus-end-directed microtubule motor activity; positive regulation of growth rate; positive regulation of multicellular organism growth; positive regulation of necrotic cell death; positive regulation of synaptic growth at neuromuscular junction; receptor clustering; regulated secretory pathway; regulation of axon extension; regulation of striated muscle contraction; reproduction; synapse; synaptic transmission, cholinergic",PF12473;PF12423;PF00225;PF16183;PF00169;,,,,,,,,,UN104_CAEEL,Caenorhabditis elegans,"anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; cell cycle [GO:0007049]; cell division [GO:0051301]; defecation [GO:0030421]; feeding behavior [GO:0007631]; microtubule-based movement [GO:0007018]; molting cycle, collagen and cuticulin-based cuticle [GO:0018996]; negative regulation of dense core granule transport [GO:1904810]; nematode larval development [GO:0002119]; neuron-neuron synaptic transmission [GO:0007270]; neuron remodeling [GO:0016322]; positive regulation of growth rate [GO:0040010]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of pharyngeal pumping [GO:1903746]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; receptor clustering [GO:0043113]; regulated exocytosis [GO:0045055]; regulation of axon extension [GO:0030516]; regulation of protein localization to synapse [GO:1902473]; regulation of striated muscle contraction [GO:0006942]; reproduction [GO:0000003]; synaptic transmission, cholinergic [GO:0007271]; vesicle-mediated transport [GO:0016192]" comp140534_c0_seq3,1317,44.3432,0.41124256,130,16,,4.00E-56,F8WLE0,Kinesin-like protein KLP6 (Kinesin-like protein 6),Kinesin-like protein KIF28P (Kinesin-like protein 6),GO:0005524; GO:0005871; GO:0003777; GO:0031966; GO:0007005; GO:0072384,ATP binding; kinesin complex; microtubule motor activity; mitochondrial membrane; mitochondrion organization; organelle transport along microtubule,PF00498;PF12423;PF00225;,4.00E-99,CHOYP_NEMVEDRAFT_V1G100691.1.2,,,,,,,KLP6_RAT,Rattus norvegicus (Rat),mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] comp140535_c2_seq2,2222,48.1998,0.34990738,72,2,,,,,,,,,4.00E-120,CHOYP_BRAFLDRAFT_120093.2.2,,,,,,,,, comp140538_c0_seq2,2799,46.2308,0.73170741,232,113,,0,Q2VJ60,E3 ubiquitin-protein ligase RNF19A (EC 6.3.2.-) (Double ring-finger protein) (Dorfin) (RING finger protein 19A),E3 ubiquitin-protein ligase RNF19A (EC 6.3.2.-) (Double ring-finger protein) (Dorfin) (RING finger protein 19A),GO:0005737; GO:0016021; GO:0016874; GO:0005815; GO:0016567; GO:0008270,cytoplasm; integral to membrane; ligase activity; microtubule organizing center; protein ubiquitination; zinc ion binding,PF01485;,2.00E-157,CHOYP_MYS.2.7,,,,,,,RN19A_PIG,Sus scrofa (Pig),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp140539_c2_seq1,901,37.2919,0.25589591,42,159,,7.00E-08,A5PKK9,Fanconi anemia-associated protein of 20 kDa,Fanconi anemia core complex-associated protein 20 (FANCA-associated protein of 20 kDa) (Fanconi anemia-associated protein of 20 kDa),GO:0043240; GO:0070530; GO:0005694; GO:0036297; GO:0046872; GO:0019985,Fanconi anaemia nuclear complex; K63-linked polyubiquitin binding; chromosome; interstrand cross-link repair; metal ion binding; translesion synthesis,PF15751;PF15750;,,,,,,,,,FAP20_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; interstrand cross-link repair [GO:0036297]; translesion synthesis [GO:0019985] comp140539_c4_seq1,295,36.9492,0.50789877,21,7,,2.00E-09,Q14191,"Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)","Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)",GO:0043138; GO:0008408; GO:0005524; GO:0043140; GO:0004003; GO:0006310; GO:0000731; GO:0051880; GO:0000403; GO:0006284; GO:0000405; GO:0007569; GO:0071480; GO:0009267; GO:0005813; GO:0006302; GO:0009378; GO:0000287; GO:0030145; GO:0010259; GO:0005730; GO:0032066; GO:0005654; GO:0051345; GO:0032403; GO:0042803; GO:0042981; GO:0040009; GO:0031297; GO:0001302; GO:0010225; GO:0006979; GO:0000723,3'-5' DNA helicase activity; 3'-5' exonuclease activity; ATP binding; ATP-dependent 3'-5' DNA helicase activity; ATP-dependent DNA helicase activity; DNA recombination; DNA synthesis involved in DNA repair; G-quadruplex DNA binding; Y-form DNA binding; base-excision repair; bubble DNA binding; cell aging; cellular response to gamma radiation; cellular response to starvation; centrosome; double-strand break repair; four-way junction helicase activity; magnesium ion binding; manganese ion binding; multicellular organismal aging; nucleolus; nucleolus to nucleoplasm transport; nucleoplasm; positive regulation of hydrolase activity; protein complex binding; protein homodimerization activity; regulation of apoptotic process; regulation of growth rate; replication fork processing; replicative cell aging; response to UV-C; response to oxidative stress; telomere maintenance,PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;,,,,,,,,,WRN_HUMAN,Homo sapiens (Human),aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; protein sumoylation [GO:0016925]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp140540_c0_seq1,3080,38.6688,0.50005131,21,16,,0,O35344,Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3),Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3),GO:0005737; GO:0005634; GO:0006606; GO:0008565,cytoplasm; nucleus; protein import into nucleus; protein transporter activity,PF00514;PF16186;PF01749;,0,CHOYP_LOC100533341.1.1,,,,,,,IMA3_MOUSE,Mus musculus (Mouse),NLS-bearing protein import into nucleus [GO:0006607] comp140540_c0_seq2,3014,38.6861,0.49179239,4,0,,2.00E-40,Q9FYP9,Importin subunit alpha-2,Importin subunit alpha-2,GO:0005634; GO:0048471; GO:0006606; GO:0008565,nucleus; perinuclear region of cytoplasm; protein import into nucleus; protein transporter activity,PF00514;,0,CHOYP_LOC100533341.1.1,,,,,,,IMA2_ORYSJ,Oryza sativa subsp. japonica (Rice),NLS-bearing protein import into nucleus [GO:0006607] comp140541_c0_seq1,2782,36.3767,0.23324955,0,0,,2.00E-25,P55937,Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2),Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2),GO:0032580; GO:0000139; GO:0017119; GO:0030154; GO:0005793; GO:0007275; GO:0005634; GO:0007283,Golgi cisterna membrane; Golgi membrane; Golgi transport complex; cell differentiation; endoplasmic reticulum-Golgi intermediate compartment; multicellular organismal development; nucleus; spermatogenesis,,,,,,,,,,GOGA3_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140541_c0_seq10,2825,35.8938,0.22402971,0,0,,6.00E-25,P55937,Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2),Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2),GO:0032580; GO:0000139; GO:0017119; GO:0030154; GO:0005793; GO:0007275; GO:0005634; GO:0007283,Golgi cisterna membrane; Golgi membrane; Golgi transport complex; cell differentiation; endoplasmic reticulum-Golgi intermediate compartment; multicellular organismal development; nucleus; spermatogenesis,,,,,,,,,,GOGA3_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140541_c0_seq2,825,32.4848,0.24684753,34,58,,1.00E-24,P55937,Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2),Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2),GO:0032580; GO:0000139; GO:0017119; GO:0030154; GO:0005793; GO:0007275; GO:0005634; GO:0007283,Golgi cisterna membrane; Golgi membrane; Golgi transport complex; cell differentiation; endoplasmic reticulum-Golgi intermediate compartment; multicellular organismal development; nucleus; spermatogenesis,,,,,,,,,,GOGA3_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140542_c0_seq1,5808,42.562,0.81447479,13,0,,2.00E-146,Q8R151,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,,,,,,,,,ZNFX1_MOUSE,Mus musculus (Mouse), comp140542_c0_seq2,4864,43.051,0.82352373,5,7,,5.00E-148,Q8R151,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,1.00E-86,CHOYP_BRAFLDRAFT_234820.1.1,,,,,,,ZNFX1_MOUSE,Mus musculus (Mouse), comp140542_c0_seq4,5714,42.8421,0.81749571,5,2,,,,,,,,,1.00E-86,CHOYP_BRAFLDRAFT_234820.1.1,1.00E-16,ruditapes_c12203,,,,,,, comp140542_c0_seq5,3011,42.7433,0.82664938,10,0,,9.00E-154,Q8R151,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,8.00E-87,CHOYP_BRAFLDRAFT_234820.1.1,2.00E-21,ruditapes_c16015,,,,,ZNFX1_MOUSE,Mus musculus (Mouse), comp140546_c1_seq1,2493,40.0321,0.33444547,183,157,,2.00E-78,Q6ZPJ3,Ubiquitin-conjugating enzyme E2 O (EC 6.3.2.19) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O),(E3-independent) E2 ubiquitin-conjugating enzyme UBE2O (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O),GO:0005524; GO:0004842,ATP binding; ubiquitin-protein ligase activity,PF00179;,4.00E-70,CHOYP_AAEL_AAEL006073.1.1,,,,,,,UBE2O_MOUSE,Mus musculus (Mouse),"positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147]" comp140549_c0_seq1,2446,38.6345,0.98502463,340,2159,,5.00E-167,Q70KH2,Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase),Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase),GO:0005975; GO:0004348; GO:0005765; GO:0006665,carbohydrate metabolic process; glucosylceramidase activity; lysosomal membrane; sphingolipid metabolic process,PF02055;PF17189;,8.00E-35,CHOYP_GLCM.1.3,1.00E-23,ruditapes_c17829,,,,,GLCM_PIG,Sus scrofa (Pig),carbohydrate metabolic process [GO:0005975]; sphingolipid metabolic process [GO:0006665] comp140549_c0_seq2,1316,39.0578,1.10554093,0,12,,3.00E-93,Q70KH2,Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase),Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase),GO:0005975; GO:0004348; GO:0005765; GO:0006665,carbohydrate metabolic process; glucosylceramidase activity; lysosomal membrane; sphingolipid metabolic process,PF02055;PF17189;,,,,,,,,,GLCM_PIG,Sus scrofa (Pig),carbohydrate metabolic process [GO:0005975]; sphingolipid metabolic process [GO:0006665] comp140550_c4_seq2,1045,41.7225,0.62899785,279,54,,5.00E-54,Q4V869,Acyl-CoA-binding domain-containing protein 6,Acyl-CoA-binding domain-containing protein 6,GO:0005737; GO:0000062; GO:0008289,cytoplasm; fatty-acyl-CoA binding; lipid binding,PF00887;PF12796;,,,,,,,,,ACBD6_XENLA,Xenopus laevis (African clawed frog), comp140551_c1_seq9,2311,37.646,0.55779252,0,0,,2.00E-12,O42204,Integral membrane protein 2B (Transmembrane protein E3-16),Integral membrane protein 2B (Transmembrane protein E3-16),GO:0000139; GO:0010008; GO:0016021; GO:0005886,Golgi membrane; endosome membrane; integral to membrane; plasma membrane,PF04089;,,,,,,,,,ITM2B_CHICK,Gallus gallus (Chicken),negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; nervous system development [GO:0007399] comp140553_c0_seq1,3798,37.9937,0.49805309,105,8,,8.00E-180,Q8NB25,Protein FAM184A,Protein FAM184A,,,,,,,,,,,,F184A_HUMAN,Homo sapiens (Human), comp140553_c0_seq2,3759,38.2016,0.51203111,107,0,,7.00E-180,Q8NB25,Protein FAM184A,Protein FAM184A,,,,5.00E-40,CHOYP_LOC590343.1.1,,,,,,,F184A_HUMAN,Homo sapiens (Human), comp140553_c0_seq3,2689,38.9736,0.43158038,7,0,,2.00E-19,Q0KK56,Protein FAM184B,Protein FAM184B,,,,3.00E-40,CHOYP_LOC590343.1.1,,,,,,,F184B_MOUSE,Mus musculus (Mouse), comp140554_c1_seq1,1835,43.5422,0.32561861,173,340,,0,Q96SZ6,CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42),CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42),GO:0051539; GO:0007420; GO:0005737; GO:0046872; GO:0045736; GO:0019901; GO:0045664; GO:0006400; GO:0016740,"4 iron, 4 sulfur cluster binding; brain development; cytoplasm; metal ion binding; negative regulation of cyclin-dependent protein serine/threonine kinase activity; protein kinase binding; regulation of neuron differentiation; tRNA modification; transferase activity",PF04055;PF01938;PF00919;,5.00E-87,CHOYP_CK5P1.1.1,,,,,,,CK5P1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; regulation of neuron differentiation [GO:0045664]; tRNA modification [GO:0006400] comp140554_c1_seq2,928,45.5819,0.38073815,9,48,,2.00E-65,B2V276,(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB (EC 2.-.-.-) (tRNA-i(6)A37 methylthiotransferase),tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC 2.8.4.3) ((Dimethylallyl)adenosine tRNA methylthiotransferase MiaB) (tRNA-i(6)A37 methylthiotransferase),GO:0051539; GO:0005737; GO:0005506; GO:0006400; GO:0016740,"4 iron, 4 sulfur cluster binding; cytoplasm; iron ion binding; tRNA modification; transferase activity",PF04055;PF01938;PF00919;,,,,,,,,,MIAB_CLOBA,Clostridium botulinum (strain Alaska E43 / Type E3),tRNA modification [GO:0006400] comp140557_c0_seq12,641,44.7738,0.78056799,8,0,,6.00E-09,P10272,Pol polyprotein [Cleaved into: Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN)],Pol polyprotein [Cleaved into: Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0015074; GO:0006310; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0090305; GO:0006508; GO:0004523; GO:0046718,DNA integration; DNA recombination; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; viral entry into host cell,PF00075;PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL_BAEVM,Baboon endogenous virus (strain M7),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp140557_c0_seq2,2972,42.5303,0.54664094,12,0,,2.00E-07,P10272,Pol polyprotein [Cleaved into: Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN)],Pol polyprotein [Cleaved into: Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0015074; GO:0006310; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0090305; GO:0006508; GO:0004523; GO:0046718,DNA integration; DNA recombination; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; viral entry into host cell,PF00075;PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL_BAEVM,Baboon endogenous virus (strain M7),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp140559_c0_seq10,3252,43.1119,0.46595339,0,0,,0,P51432,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)",GO:0005509; GO:0035556; GO:0016042; GO:0005634; GO:0004435; GO:0043234; GO:0003073; GO:0004871,calcium ion binding; intracellular signal transduction; lipid catabolic process; nucleus; phosphatidylinositol phospholipase C activity; protein complex; regulation of systemic arterial blood pressure; signal transducer activity,PF00168;PF09279;PF00388;PF00387;PF08703;,0,CHOYP_LOC100901017.1.2,,,,,,,PLCB3_MOUSE,Mus musculus (Mouse),chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; post-Golgi vesicle-mediated transport [GO:0006892]; regulation of systemic arterial blood pressure [GO:0003073] comp140559_c0_seq11,3500,43.4,0.50054927,0,0,,1.00E-47,Q8N3E9,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)",GO:0001525; GO:0005509; GO:0032154; GO:0005829; GO:0043647; GO:0035556; GO:0060716; GO:0016042; GO:0004435; GO:0005543; GO:0005886; GO:0042127; GO:0004871,angiogenesis; calcium ion binding; cleavage furrow; cytosol; inositol phosphate metabolic process; intracellular signal transduction; labyrinthine layer blood vessel development; lipid catabolic process; phosphatidylinositol phospholipase C activity; phospholipid binding; plasma membrane; regulation of cell proliferation; signal transducer activity,PF00168;PF00388;PF00387;,,,,,,,,,PLCD3_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipid catabolic process [GO:0016042]; regulation of cell proliferation [GO:0042127] comp140559_c0_seq12,1765,41.8697,0.37554091,0,0,,1.00E-179,P25455,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)",GO:0005509; GO:0007629; GO:0035556; GO:0016042; GO:0004435; GO:0004871,calcium ion binding; flight behavior; intracellular signal transduction; lipid catabolic process; phosphatidylinositol phospholipase C activity; signal transducer activity,PF09279;PF00388;PF00387;,0,CHOYP_LOC100901017.1.2,,,,,,,PIP1_DROME,Drosophila melanogaster (Fruit fly),diacylglycerol biosynthetic process [GO:0006651]; flight behavior [GO:0007629]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; neuron cellular homeostasis [GO:0070050]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of neuromuscular synaptic transmission [GO:1900073] comp140559_c0_seq14,2975,43.395,0.50101016,0,0,,0,Q9QW07,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)",GO:0005509; GO:0005737; GO:0035556; GO:0016042; GO:0043267; GO:0004435; GO:0007602; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid catabolic process; negative regulation of potassium ion transport; phosphatidylinositol phospholipase C activity; phototransduction; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,0,CHOYP_LOC100888919.1.1,,,,,,,PLCB4_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602] comp140559_c0_seq16,2105,42.6128,0.39946101,0,0,,2.00E-56,P21671,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (PLC-85) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-2) (PLC-delta-2) (Phospholipase C-delta-4) (PLC-delta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (PLC-85) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-2) (PLC-delta-2) (Phospholipase C-delta-4) (PLC-delta-4)",GO:0005509; GO:0005783; GO:0035556; GO:0016042; GO:0016020; GO:0005634; GO:0004435; GO:0005543; GO:0004871,calcium ion binding; endoplasmic reticulum; intracellular signal transduction; lipid catabolic process; membrane; nucleus; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF09279;PF00169;PF00388;PF00387;,0,CHOYP_LOC100901017.2.2,,,,,,,PLCD4_BOVIN,Bos taurus (Bovine),acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488] comp140559_c0_seq17,3494,43.2742,0.50420483,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,0,CHOYP_LOC100901017.1.2,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq2,2117,42.5602,0.39816372,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,,,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq20,1783,42.0639,0.36841405,0,0,,3.00E-49,P16885,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)",GO:0030183; GO:0050853; GO:0038095; GO:0038096; GO:0050852; GO:0016055; GO:0032237; GO:0019722; GO:0005829; GO:0002316; GO:0045087; GO:0043647; GO:0032959; GO:0043069; GO:0006661; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0030168; GO:0010468; GO:0051209; GO:0032496; GO:0004871,B cell differentiation; B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell receptor signaling pathway; Wnt receptor signaling pathway; activation of store-operated calcium channel activity; calcium-mediated signaling; cytosol; follicular B cell differentiation; innate immune response; inositol phosphate metabolic process; inositol trisphosphate biosynthetic process; negative regulation of programmed cell death; phosphatidylinositol biosynthetic process; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; platelet activation; regulation of gene expression; release of sequestered calcium ion into cytosol; response to lipopolysaccharide; signal transducer activity,PF00168;PF00388;PF00387;PF00017;PF00018;,0,CHOYP_LOC100901017.2.2,,,,,,,PLCG2_HUMAN,Homo sapiens (Human),activation of store-operated calcium channel activity [GO:0032237]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; follicular B cell differentiation [GO:0002316]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate biosynthetic process [GO:0032959]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid catabolic process [GO:0009395]; platelet activation [GO:0030168]; positive regulation of receptor internalization [GO:0002092]; positive regulation of type I interferon production [GO:0032481]; regulation of gene expression [GO:0010468]; release of sequestered calcium ion into cytosol [GO:0051209]; response to lipopolysaccharide [GO:0032496]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; Wnt signaling pathway [GO:0016055] comp140559_c0_seq22,3270,43.211,0.46137266,0,0,,1.00E-53,Q4R6L3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)",GO:0005509; GO:0005783; GO:0035556; GO:0016042; GO:0016020; GO:0005634; GO:0004435; GO:0005543; GO:0004871,calcium ion binding; endoplasmic reticulum; intracellular signal transduction; lipid catabolic process; membrane; nucleus; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF13202;PF09279;PF00169;PF00388;PF00387;,,,,,,,,,PLCD4_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488] comp140559_c0_seq23,2099,42.4011,0.4044685,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,0,CHOYP_LOC100901017.1.2,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq24,3240,43.1481,0.4669097,0,0,,0,Q9QW07,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)",GO:0005509; GO:0005737; GO:0035556; GO:0016042; GO:0043267; GO:0004435; GO:0007602; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid catabolic process; negative regulation of potassium ion transport; phosphatidylinositol phospholipase C activity; phototransduction; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,0,CHOYP_LOC100888919.1.1,,,,,,,PLCB4_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602] comp140559_c0_seq25,3443,43.131,0.48391975,0,0,,0,Q99JE6,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)",GO:0007186; GO:0005509; GO:0005829; GO:0035556; GO:0004435; GO:0009395; GO:0006892; GO:0042383; GO:0004871,G-protein coupled receptor signaling pathway; calcium ion binding; cytosol; intracellular signal transduction; phosphatidylinositol phospholipase C activity; phospholipid catabolic process; post-Golgi vesicle-mediated transport; sarcolemma; signal transducer activity,PF00168;PF09279;PF00388;PF00387;PF08703;,,,,,,,,,PLCB3_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; post-Golgi vesicle-mediated transport [GO:0006892] comp140559_c0_seq26,1753,41.9281,0.37706461,0,0,,1.00E-169,Q01970,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)",GO:0005509; GO:0005829; GO:0043647; GO:0035556; GO:0016042; GO:0016020; GO:0004435; GO:0004629; GO:0043234; GO:0003073; GO:0004871; GO:0007268,calcium ion binding; cytosol; inositol phosphate metabolic process; intracellular signal transduction; lipid catabolic process; membrane; phosphatidylinositol phospholipase C activity; phospholipase C activity; protein complex; regulation of systemic arterial blood pressure; signal transducer activity; synaptic transmission,PF00168;PF09279;PF00388;PF00387;PF08703;,0,CHOYP_LOC100901017.1.2,,,,,,,PLCB3_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; post-Golgi vesicle-mediated transport [GO:0006892]; regulation of systemic arterial blood pressure [GO:0003073]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]" comp140559_c0_seq28,2987,43.3545,0.49992118,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,0,CHOYP_LOC100888919.1.1,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq3,3512,43.3656,0.49961501,0,0,,3.00E-81,Q2VRL0,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1)",GO:0005509; GO:0035556; GO:0016042; GO:0007275; GO:0005634; GO:0048471; GO:0004435; GO:0004871; GO:0007338,calcium ion binding; intracellular signal transduction; lipid catabolic process; multicellular organismal development; nucleus; perinuclear region of cytoplasm; phosphatidylinositol phospholipase C activity; signal transducer activity; single fertilization,PF00168;PF09279;PF00388;PF00387;,,,,,,,,,PLCZ1_CHICK,Gallus gallus (Chicken),calcium ion transport [GO:0006816]; egg activation [GO:0007343]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; multicellular organism development [GO:0007275] comp140559_c0_seq30,3482,43.3084,0.50515763,0,0,,4.00E-172,P25455,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)",GO:0005509; GO:0007629; GO:0035556; GO:0016042; GO:0004435; GO:0004871,calcium ion binding; flight behavior; intracellular signal transduction; lipid catabolic process; phosphatidylinositol phospholipase C activity; signal transducer activity,PF09279;PF00388;PF00387;,0,CHOYP_LOC100901017.1.2,,,,,,,PIP1_DROME,Drosophila melanogaster (Fruit fly),diacylglycerol biosynthetic process [GO:0006651]; flight behavior [GO:0007629]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; neuron cellular homeostasis [GO:0070050]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of neuromuscular synaptic transmission [GO:1900073] comp140559_c0_seq31,2993,43.5015,0.49564853,0,0,,,,,,,,,0,CHOYP_LOC100901017.2.2,,,,,,,,, comp140559_c0_seq32,3309,43.3968,0.48408803,0,0,,9.00E-48,P16885,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)",GO:0030183; GO:0050853; GO:0038095; GO:0038096; GO:0050852; GO:0016055; GO:0032237; GO:0019722; GO:0005829; GO:0002316; GO:0045087; GO:0043647; GO:0032959; GO:0043069; GO:0006661; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0030168; GO:0010468; GO:0051209; GO:0032496; GO:0004871,B cell differentiation; B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell receptor signaling pathway; Wnt receptor signaling pathway; activation of store-operated calcium channel activity; calcium-mediated signaling; cytosol; follicular B cell differentiation; innate immune response; inositol phosphate metabolic process; inositol trisphosphate biosynthetic process; negative regulation of programmed cell death; phosphatidylinositol biosynthetic process; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; platelet activation; regulation of gene expression; release of sequestered calcium ion into cytosol; response to lipopolysaccharide; signal transducer activity,PF00168;PF00388;PF00387;PF00017;PF00018;,,,,,,,,,PLCG2_HUMAN,Homo sapiens (Human),activation of store-operated calcium channel activity [GO:0032237]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; follicular B cell differentiation [GO:0002316]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate biosynthetic process [GO:0032959]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid catabolic process [GO:0009395]; platelet activation [GO:0030168]; positive regulation of receptor internalization [GO:0002092]; positive regulation of type I interferon production [GO:0032481]; regulation of gene expression [GO:0010468]; release of sequestered calcium ion into cytosol [GO:0051209]; response to lipopolysaccharide [GO:0032496]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; Wnt signaling pathway [GO:0016055] comp140559_c0_seq33,3432,43.1527,0.48499914,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,5.00E-71,CHOYP_PLCB4.1.2,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq4,3303,43.2637,0.48783373,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,0,CHOYP_LOC100901017.1.2,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq5,2087,42.4533,0.40581024,0,0,,4.00E-177,Q15147,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)",GO:0005509; GO:0005829; GO:0030425; GO:0043647; GO:0035556; GO:0016042; GO:0005634; GO:0004435; GO:0004629; GO:0014069; GO:0004871; GO:0005790,calcium ion binding; cytosol; dendrite; inositol phosphate metabolic process; intracellular signal transduction; lipid catabolic process; nucleus; phosphatidylinositol phospholipase C activity; phospholipase C activity; postsynaptic density; signal transducer activity; smooth endoplasmic reticulum,PF00168;PF06631;PF09279;PF00388;PF00387;,0,CHOYP_LOC100901017.1.2,,,,,,,PLCB4_HUMAN,Homo sapiens (Human),inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267] comp140559_c0_seq6,3291,43.2999,0.48880833,0,0,,0,Q9QW07,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)",GO:0005509; GO:0005737; GO:0035556; GO:0016042; GO:0043267; GO:0004435; GO:0007602; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid catabolic process; negative regulation of potassium ion transport; phosphatidylinositol phospholipase C activity; phototransduction; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,0,CHOYP_LOC100888919.1.1,,,,,,,PLCB4_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602] comp140559_c0_seq7,1771,42.1231,0.36987625,0,0,,5.00E-177,P25455,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)",GO:0005509; GO:0007629; GO:0035556; GO:0016042; GO:0004435; GO:0004871,calcium ion binding; flight behavior; intracellular signal transduction; lipid catabolic process; phosphatidylinositol phospholipase C activity; signal transducer activity,PF09279;PF00388;PF00387;,0,CHOYP_LOC100901017.2.2,,,,,,,PIP1_DROME,Drosophila melanogaster (Fruit fly),diacylglycerol biosynthetic process [GO:0006651]; flight behavior [GO:0007629]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; neuron cellular homeostasis [GO:0070050]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of neuromuscular synaptic transmission [GO:1900073] comp140559_c0_seq8,3259,43.2341,0.46245075,0,0,,0,Q9Z1B3,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)",GO:0007213; GO:0000086; GO:0005096; GO:0060466; GO:0005509; GO:0005516; GO:0007155; GO:0021987; GO:0005737; GO:0019899; GO:0030218; GO:0045444; GO:0007215; GO:0008286; GO:0048009; GO:0070498; GO:0035722; GO:0035723; GO:0035556; GO:0016042; GO:0006397; GO:0030225; GO:0007613; GO:2000438; GO:0045892; GO:0000790; GO:0031965; GO:0016607; GO:0001556; GO:0046488; GO:0004435; GO:0005546; GO:0005886; GO:2000560; GO:1900087; GO:0046330; GO:2000344; GO:0048639; GO:0040019; GO:0032735; GO:0045663; GO:0032417; GO:0045893; GO:0042803; GO:0008277; GO:0080154; GO:0004871,"G-protein coupled acetylcholine receptor signaling pathway; G2/M transition of mitotic cell cycle; GTPase activator activity; activation of meiosis involved in egg activation; calcium ion binding; calmodulin binding; cell adhesion; cerebral cortex development; cytoplasm; enzyme binding; erythrocyte differentiation; fat cell differentiation; glutamate receptor signaling pathway; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; interleukin-1-mediated signaling pathway; interleukin-12-mediated signaling pathway; interleukin-15-mediated signaling pathway; intracellular signal transduction; lipid catabolic process; mRNA processing; macrophage differentiation; memory; negative regulation of monocyte extravasation; negative regulation of transcription, DNA-dependent; nuclear chromatin; nuclear membrane; nuclear speck; oocyte maturation; phosphatidylinositol metabolic process; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of CD24 biosynthetic process; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of acrosome reaction; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of interleukin-12 production; positive regulation of myoblast differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein homodimerization activity; regulation of G-protein coupled receptor protein signaling pathway; regulation of fertilization; signal transducer activity",PF06631;PF09279;PF00388;PF00387;PF08703;,,,,,,,,,PLCB1_MOUSE,Mus musculus (Mouse),"activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]" comp140559_c0_seq9,3321,43.3604,0.48313352,0,0,,0,Q99JE6,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)",GO:0007186; GO:0005509; GO:0005829; GO:0035556; GO:0004435; GO:0009395; GO:0006892; GO:0042383; GO:0004871,G-protein coupled receptor signaling pathway; calcium ion binding; cytosol; intracellular signal transduction; phosphatidylinositol phospholipase C activity; phospholipid catabolic process; post-Golgi vesicle-mediated transport; sarcolemma; signal transducer activity,PF00168;PF09279;PF00388;PF00387;PF08703;,,,,,,,,,PLCB3_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; post-Golgi vesicle-mediated transport [GO:0006892] comp140561_c0_seq3,1562,42.8937,0.8362466,38,479,,2.00E-87,Q8K2I4,Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase),Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase),GO:0004567; GO:0006516; GO:0005764; GO:0046355; GO:0005537,beta-mannosidase activity; glycoprotein catabolic process; lysosome; mannan catabolic process; mannose binding,PF02836;PF02837;,2.00E-41,CHOYP_MANBA.2.2,,,,,,,MANBA_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516] comp140561_c1_seq1,545,44.4037,0.92282001,8,86,,5.00E-46,Q5B7W2,Beta-mannosidase B (EC 3.2.1.25) (Mannanase B) (Mannase B),Beta-mannosidase B (EC 3.2.1.25) (Mannanase B) (Mannase B),GO:0004567; GO:0005576; GO:0046355,beta-mannosidase activity; extracellular region; mannan catabolic process,PF00703;,9.00E-20,CHOYP_BRAFLDRAFT_65994.1.1,,,,,,,MANBB_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),mannan catabolic process [GO:0046355] comp140563_c0_seq1,2902,39.5245,0.46448577,0,0,,5.00E-60,Q5ZJ54,T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta),T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta),GO:0005524; GO:0005737; GO:0006457,ATP binding; cytoplasm; protein folding,PF00118;,,,,,,,,,TCPZ_CHICK,Gallus gallus (Chicken),protein folding [GO:0006457]; toxin transport [GO:1901998] comp140563_c0_seq10,2619,40.9317,0.44406786,0,15,,,,,,,,,0,CHOYP_LOC100115577.1.1,,,,,,,,, comp140563_c0_seq11,2343,42.0401,0.46069576,0,0,,0,P28480,T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),GO:0005524; GO:0005794; GO:0001669; GO:0007339; GO:0005832; GO:0000792; GO:0005874; GO:0005720; GO:0000242; GO:0006457; GO:0007286; GO:0002199,ATP binding; Golgi apparatus; acrosomal vesicle; binding of sperm to zona pellucida; chaperonin-containing T-complex; heterochromatin; microtubule; nuclear heterochromatin; pericentriolar material; protein folding; spermatid development; zona pellucida receptor complex,PF00118;,,,,,,,,,TCPA_RAT,Rattus norvegicus (Rat),binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] comp140563_c0_seq12,2900,39.4138,0.45901619,0,0,,0,P28480,T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),GO:0005524; GO:0005794; GO:0001669; GO:0007339; GO:0005832; GO:0000792; GO:0005874; GO:0005720; GO:0000242; GO:0006457; GO:0007286; GO:0002199,ATP binding; Golgi apparatus; acrosomal vesicle; binding of sperm to zona pellucida; chaperonin-containing T-complex; heterochromatin; microtubule; nuclear heterochromatin; pericentriolar material; protein folding; spermatid development; zona pellucida receptor complex,PF00118;,0,CHOYP_LOC100115577.1.1,,,,,,,TCPA_RAT,Rattus norvegicus (Rat),binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] comp140563_c0_seq2,2394,41.8129,0.45624972,0,0,,0,P28480,T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),GO:0005524; GO:0005794; GO:0001669; GO:0007339; GO:0005832; GO:0000792; GO:0005874; GO:0005720; GO:0000242; GO:0006457; GO:0007286; GO:0002199,ATP binding; Golgi apparatus; acrosomal vesicle; binding of sperm to zona pellucida; chaperonin-containing T-complex; heterochromatin; microtubule; nuclear heterochromatin; pericentriolar material; protein folding; spermatid development; zona pellucida receptor complex,PF00118;,,,,,,,,,TCPA_RAT,Rattus norvegicus (Rat),binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] comp140563_c0_seq3,2884,39.4938,0.46837638,0,0,,2.00E-06,Q8PW06,60 kDa chaperonin (GroEL protein) (Protein Cpn60),60 kDa chaperonin (GroEL protein) (Protein Cpn60),GO:0005524; GO:0005737; GO:0042026,ATP binding; cytoplasm; protein refolding,PF00118;,2.00E-17,CHOYP_TCPD.1.1,,,,,,,CH60_METMA,Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia),protein refolding [GO:0042026] comp140563_c0_seq4,2376,41.7508,0.45150562,0,0,,2.00E-06,A9WFA3,60 kDa chaperonin 2 (GroEL protein 2) (Protein Cpn60 2),60 kDa chaperonin 2 (GroEL protein 2) (Protein Cpn60 2),GO:0005524; GO:0005737; GO:0042026,ATP binding; cytoplasm; protein refolding,PF00118;,0,CHOYP_LOC100115577.1.1,,,,,,,CH602_CHLAA,Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl),protein refolding [GO:0042026] comp140563_c0_seq6,2918,39.5134,0.46268089,0,0,,0,P28480,T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha),GO:0005524; GO:0005794; GO:0001669; GO:0007339; GO:0005832; GO:0000792; GO:0005874; GO:0005720; GO:0000242; GO:0006457; GO:0007286; GO:0002199,ATP binding; Golgi apparatus; acrosomal vesicle; binding of sperm to zona pellucida; chaperonin-containing T-complex; heterochromatin; microtubule; nuclear heterochromatin; pericentriolar material; protein folding; spermatid development; zona pellucida receptor complex,PF00118;,,,,,,,,,TCPA_RAT,Rattus norvegicus (Rat),binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] comp140563_c0_seq8,2601,41.0611,0.45384105,0,0,,4.00E-73,Q9LKI7,T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma),T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma),GO:0005524; GO:0005737; GO:0006457,ATP binding; cytoplasm; protein folding,PF00118;,2.00E-17,CHOYP_TCPD.1.1,,,,,,,TCPG_THAWE,Thalassiosira weissflogii (Marine diatom),protein folding [GO:0006457] comp140563_c0_seq9,2361,41.9737,0.44857861,0,0,,4.00E-63,Q76NU3,T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta),T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta),GO:0005524; GO:0005832; GO:0045335; GO:0006457; GO:0051082,ATP binding; chaperonin-containing T-complex; phagocytic vesicle; protein folding; unfolded protein binding,PF00118;,0,CHOYP_LOC100115577.1.1,,,,,,,TCPZ_DICDI,Dictyostelium discoideum (Slime mold),protein folding [GO:0006457] comp140568_c0_seq3,1688,38.9218,0.44031075,97,243,,2.00E-39,Q8BTG3,T-complex protein 11-like protein 1,T-complex protein 11-like protein 1,GO:0005874,microtubule,PF05794;,7.00E-21,CHOYP_LOC100372245.1.1,,,,,,,T11L1_MOUSE,Mus musculus (Mouse), comp140569_c0_seq1,3258,32.8422,0.53815728,3682,38959,,2.00E-61,Q03105,V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (15 kDa mediatophore protein) (Vacuolar proton pump 16 kDa proteolipid subunit),V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (15 kDa mediatophore protein) (Vacuolar proton pump 16 kDa proteolipid subunit),GO:0015991; GO:0015078; GO:0016021; GO:0033179; GO:0005774,"ATP hydrolysis coupled proton transport; hydrogen ion transmembrane transporter activity; integral to membrane; proton-transporting V-type ATPase, V0 domain; vacuolar membrane",PF00137;,8.00E-100,CHOYP_NEMVEDRAFT_V1G162114.1.2,2.00E-148,ruditapes2_c865,,,,,VATL_TORMA,Torpedo marmorata (Marbled electric ray),ATP hydrolysis coupled proton transport [GO:0015991] comp140570_c0_seq2,1758,34.2435,0.44989728,134,1370,,2.00E-33,P51572,B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28),B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28),GO:0000139; GO:0002474; GO:0035584; GO:0006921; GO:0005829; GO:0007204; GO:0051561; GO:0033116; GO:0006955; GO:0071556; GO:0005887; GO:0006886; GO:0005811; GO:0043280; GO:2001244; GO:0005102; GO:0032471; GO:0007283; GO:0016192,Golgi membrane; antigen processing and presentation of peptide antigen via MHC class I; calcium-mediated signaling using intracellular calcium source; cellular component disassembly involved in execution phase of apoptosis; cytosol; elevation of cytosolic calcium ion concentration; elevation of mitochondrial calcium ion concentration; endoplasmic reticulum-Golgi intermediate compartment membrane; immune response; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; intracellular protein transport; lipid particle; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of intrinsic apoptotic signaling pathway; receptor binding; reduction of endoplasmic reticulum calcium ion concentration; spermatogenesis; vesicle-mediated transport,PF05529;,1.00E-24,CHOYP_BAP31.1.1,,,,,,,BAP31_HUMAN,Homo sapiens (Human),"antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; protein localization to endoplasmic reticulum exit site [GO:0070973]; spermatogenesis [GO:0007283]" comp140574_c2_seq2,1928,32.2614,0.48754713,23,153,,6.00E-51,Q9VY28,"Probable 28S ribosomal protein S25, mitochondrial (MRP-S25) (S25mt)","Probable 28S ribosomal protein S25, mitochondrial (MRP-S25) (S25mt)",GO:0005763; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; structural constituent of ribosome; translation,PF05047;,,,,,,,,,RT25_DROME,Drosophila melanogaster (Fruit fly),translation [GO:0006412] comp140575_c1_seq1,1860,38.2796,0.56283095,259,863,,1.00E-54,Q9JME5,AP-3 complex subunit beta-2 (Adapter-related protein complex 3 subunit beta-2) (Adaptor protein complex AP-3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain),AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain),GO:0030123; GO:0005794; GO:0008089; GO:0048490; GO:0030665; GO:0006897; GO:0006886; GO:0005634; GO:0005802,AP-3 adaptor complex; Golgi apparatus; anterograde axon cargo transport; anterograde synaptic vesicle transport; clathrin-coated vesicle membrane; endocytosis; intracellular protein transport; nucleus; trans-Golgi network,PF01602;PF14796;,2.00E-41,CHOYP_BRAFLDRAFT_58684.1.1,,,,,,,AP3B2_MOUSE,Mus musculus (Mouse),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp140576_c2_seq1,3327,32.4917,0.49069729,36,139,,,,,,,,,5.00E-71,CHOYP_LOC100865976.1.1,,,,,,,,, comp140576_c2_seq2,3341,32.4454,0.48999595,46,150,,1.00E-77,Q6DER1,Malignant T-cell-amplified sequence 1 (MCT-1),Malignant T-cell-amplified sequence 1 (MCT-1),GO:0003723; GO:0007049; GO:0005737; GO:0040008; GO:0006355; GO:0006351,"RNA binding; cell cycle; cytoplasm; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01472;,5.00E-71,CHOYP_LOC100865976.1.1,,,,,,,MCTS1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell cycle [GO:0007049]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140577_c0_seq1,2188,41.2249,0.40089202,24,130,,7.00E-154,Q95K79,Alkylated DNA repair protein alkB homolog 8 (EC 1.14.11.-) (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.-) (EC 2.1.1.229),Alkylated DNA repair protein alkB homolog 8 (EC 1.14.11.-) (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.-) (EC 2.1.1.229),GO:0003723; GO:0005829; GO:0046872; GO:0000166; GO:0005634; GO:0016706; GO:0006974; GO:0016300,"RNA binding; cytosol; metal ion binding; nucleotide binding; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; response to DNA damage stimulus; tRNA (uracil) methyltransferase activity",PF13532;PF09004;PF08241;PF00076;,,,,,,,,,ALKB8_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cellular response to DNA damage stimulus [GO:0006974]; oxidation-reduction process [GO:0055114]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] comp140577_c0_seq2,2080,41.0577,0.36716519,21,163,,2.00E-41,Q08DH3,Putative methyltransferase KIAA1456 homolog (EC 2.1.1.-),Probable tRNA methyltransferase 9-like protein (TRM9L) (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF08241;,1.00E-82,CHOYP_ALKB8.1.2,,,,,,,K1456_BOVIN,Bos taurus (Bovine),tRNA processing [GO:0008033] comp140583_c0_seq4,1870,35.4011,0.34207264,8,18,,2.00E-30,P70280,Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1),Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1),GO:0006888; GO:0005794; GO:0043001; GO:0031201; GO:0045177; GO:0017156; GO:0030054; GO:0005789; GO:0008333; GO:0043308; GO:0016021; GO:0031902; GO:0005765; GO:0043005; GO:0043312; GO:0048471; GO:0045335; GO:0030670; GO:0006911; GO:1900483; GO:0045202; GO:0030658; GO:0034197; GO:0006906; GO:0048280,"ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi to plasma membrane protein transport; SNARE complex; apical part of cell; calcium ion-dependent exocytosis; cell junction; endoplasmic reticulum membrane; endosome to lysosome transport; eosinophil degranulation; integral to membrane; late endosome membrane; lysosomal membrane; neuron projection; neutrophil degranulation; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; phagocytosis, engulfment; regulation of protein targeting to vacuolar membrane; synapse; transport vesicle membrane; triglyceride transport; vesicle fusion; vesicle fusion with Golgi apparatus",PF13774;PF00957;,,,,,,,,,VAMP7_MOUSE,Mus musculus (Mouse),"calcium ion regulated exocytosis [GO:0017156]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; Golgi to plasma membrane protein transport [GO:0043001]; natural killer cell degranulation [GO:0043320]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of histamine secretion by mast cell [GO:1903595]; regulation of protein targeting to vacuolar membrane [GO:1900483]; SNARE complex assembly [GO:0035493]; triglyceride transport [GO:0034197]; vesicle fusion [GO:0006906]; vesicle fusion with Golgi apparatus [GO:0048280]; vesicle-mediated transport [GO:0016192]; vesicle transport along microtubule [GO:0047496]" comp140583_c0_seq6,1883,35.3691,0.32330211,0,0,,7.00E-08,O60073,Synaptobrevin homolog ykt6 (EC 2.3.1.-),Synaptobrevin homolog ykt6 (EC 2.3.1.-),GO:0005484; GO:0005829; GO:0016021; GO:0006886; GO:0005634; GO:0005886; GO:0016740; GO:0016192,SNAP receptor activity; cytosol; integral to membrane; intracellular protein transport; nucleus; plasma membrane; transferase activity; vesicle-mediated transport,PF13774;PF00957;,,,,,,,,,YKT6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] comp140583_c0_seq8,1723,35.2873,0.29894236,0,0,,1.00E-12,Q92356,Synaptobrevin homolog 1,Synaptobrevin homolog 1,GO:0005794; GO:0005484; GO:0051285; GO:0032153; GO:0030659; GO:0006897; GO:0005783; GO:0016021; GO:0006886; GO:0000281,Golgi apparatus; SNAP receptor activity; cell cortex of cell tip; cell division site; cytoplasmic vesicle membrane; endocytosis; endoplasmic reticulum; integral to membrane; intracellular protein transport; mitotic cytokinesis,PF00957;,,,,,,,,,SYB1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),endocytosis [GO:0006897]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] comp140584_c1_seq12,1822,41.1087,0.47021253,0,0,,1.00E-10,Q9CY57,Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),GO:0003723; GO:0005730; GO:0005654; GO:0006355; GO:0006351,"RNA binding; nucleolus; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13865;,,,,,,,,,FOP_MOUSE,Mus musculus (Mouse),"mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140584_c1_seq13,1455,40.1375,0.44989392,0,0,,,,,,,,,,,6.00E-19,ruditapes_c27781,,,,,,, comp140584_c1_seq5,1744,40.6537,0.40210695,0,0,,4.00E-11,Q9CY57,Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),GO:0003723; GO:0005730; GO:0005654; GO:0006355; GO:0006351,"RNA binding; nucleolus; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13865;,,,,,,,,,FOP_MOUSE,Mus musculus (Mouse),"mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140584_c1_seq6,1807,41.0625,0.46261303,17,47,,4.00E-11,Q9CY57,Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),GO:0003723; GO:0005730; GO:0005654; GO:0006355; GO:0006351,"RNA binding; nucleolus; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13865;,,,,,,,,,FOP_MOUSE,Mus musculus (Mouse),"mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140584_c1_seq9,1689,41.3854,0.38630874,0,0,,6.00E-10,Q9Y3Y2,Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG),GO:0003723; GO:0005654; GO:0005634; GO:0006355; GO:0006351,"RNA binding; nucleoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13865;,,,,,,,,,CHTOP_HUMAN,Homo sapiens (Human),"mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; RNA export from nucleus [GO:0006405]; termination of RNA polymerase II transcription [GO:0006369]" comp140585_c0_seq10,1591,41.9233,0.49050331,0,0,,7.00E-14,P56276,Telokin,Telokin,,,PF07679;,,,,,,,,,MYLK_MELGA,Meleagris gallopavo (Common turkey), comp140585_c0_seq11,575,48.6957,0.64682958,0,5,,3.00E-08,P97798,Neogenin,Neogenin,GO:0045296; GO:0007155; GO:0016021; GO:0007520; GO:0005886; GO:0004872; GO:0006355,"cadherin binding; cell adhesion; integral to membrane; myoblast fusion; plasma membrane; receptor activity; regulation of transcription, DNA-dependent",PF00041;PF07679;PF13895;PF06583;,2.00E-28,CHOYP_TTN.8.9,,,,,,,NEO1_MOUSE,Mus musculus (Mouse),"axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; myoblast fusion [GO:0007520]; negative regulation of protein secretion [GO:0050709]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of transcription, DNA-templated [GO:0006355]" comp140585_c0_seq13,1708,42.3888,0.55103658,0,0,,8.00E-07,Q62234,Myomesin-1 (Myomesin family member 1) (Skelemin),Myomesin-1 (Myomesin family member 1) (Skelemin),GO:0031430; GO:0005856; GO:0006936; GO:0032982; GO:0042803; GO:0005200,M band; cytoskeleton; muscle contraction; myosin filament; protein homodimerization activity; structural constituent of cytoskeleton,PF00041;PF07679;,,,,,,,,,MYOM1_MOUSE,Mus musculus (Mouse),mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp140585_c0_seq14,1737,43.293,0.55447655,0,0,,1.00E-41,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,2.00E-29,CHOYP_TITIN.19.19,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp140585_c0_seq2,1749,43.968,0.59308382,0,0,,4.00E-23,Q63638,Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1),GO:0005524; GO:0042692; GO:0005634; GO:0004674,ATP binding; muscle cell differentiation; nucleus; protein serine/threonine kinase activity,PF07679;PF00069;,,,,,,,,,SPEG_RAT,Rattus norvegicus (Rat),muscle cell differentiation [GO:0042692] comp140585_c0_seq3,2774,46.8998,0.65810077,13,0,,5.00E-84,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,8.00E-105,CHOYP_TITIN.19.19,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp140585_c0_seq4,3419,46.5048,0.60265853,0,0,,9.00E-83,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,,,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp140585_c0_seq5,1603,42.67,0.52515874,0,0,,5.00E-12,Q9Z2J4,Nexilin,Nexilin,GO:0030018; GO:0051015; GO:0005924; GO:0005856; GO:0030334; GO:0051493; GO:0008307,Z disc; actin filament binding; cell-substrate adherens junction; cytoskeleton; regulation of cell migration; regulation of cytoskeleton organization; structural constituent of muscle,PF07679;,,,,,,,,,NEXN_RAT,Rattus norvegicus (Rat),cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] comp140585_c0_seq6,3407,46.1697,0.58604203,0,0,,2.00E-75,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp140585_c0_seq7,1209,47.4773,0.7092879,65,23,,2.00E-17,Q8N9C0,Immunoglobulin superfamily member 22 (IgSF22),Immunoglobulin superfamily member 22 (IgSF22),,,PF00041;PF07679;,,,7.00E-30,ruditapes_c21461,,,,,IGS22_HUMAN,Homo sapiens (Human), comp140585_c0_seq8,1104,43.2065,0.72016194,0,0,,2.00E-19,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,1.00E-29,CHOYP_TITIN.19.19,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp140585_c0_seq9,1696,41.6863,0.49231233,0,0,,4.00E-12,Q7TPW1,Nexilin (F-actin-binding protein),Nexilin (F-actin-binding protein),GO:0030018; GO:0005912; GO:0005856; GO:0030334; GO:0051493; GO:0008307,Z disc; adherens junction; cytoskeleton; regulation of cell migration; regulation of cytoskeleton organization; structural constituent of muscle,PF07679;,,,1.00E-60,ruditapes_c15534,,,,,NEXN_MOUSE,Mus musculus (Mouse),cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] comp140587_c0_seq1,5682,34.7941,0.55467507,391,388,,5.00E-98,O61492,Flotillin-2,Flotillin-2,GO:0007155; GO:0016600; GO:0035011; GO:0005198,cell adhesion; flotillin complex; melanotic encapsulation of foreign target; structural molecule activity,PF01145;PF15975;,0,CHOYP_FLOT1.2.2,,,,,,,FLOT2_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; melanotic encapsulation of foreign target [GO:0035011] comp140587_c0_seq2,5682,34.7941,0.55374937,362,427,,0,O61491,Flotillin-1,Flotillin-1,GO:0016600; GO:0007275; GO:0005198,flotillin complex; multicellular organismal development; structural molecule activity,PF01145;PF15975;,0,CHOYP_FLOT1.2.2,,,,,,,FLOT1_DROME,Drosophila melanogaster (Fruit fly),multicellular organism development [GO:0007275] comp140588_c1_seq4,1445,31.9031,0.3843702,136,502,,,,,,,,,,,2.00E-12,ruditapes_c2278,,,,,,, comp140592_c0_seq1,1545,44.5955,0.32567128,259,86,,9.00E-16,Q7TPV2,E3 ubiquitin-protein ligase DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog),E3 ubiquitin-protein ligase DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog),GO:0003723; GO:0005737; GO:0016874; GO:0019902; GO:0016567; GO:0008270,RNA binding; cytoplasm; ligase activity; phosphatase binding; protein ubiquitination; zinc ion binding,PF13639;,,,,,,,,,DZIP3_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp140596_c0_seq1,2181,42.5034,0.41848486,89,124,,9.00E-122,Q5SRX1,TOM1-like protein 2 (Target of Myb-like protein 2),TOM1-like protein 2 (Target of Myb-like protein 2),GO:0005622; GO:0006886,intracellular; intracellular protein transport,PF03127;PF00790;,,,,,,,,,TM1L2_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; negative regulation of mitotic nuclear division [GO:0045839]; signal transduction [GO:0007165] comp140596_c0_seq2,1503,46.1743,0.43945789,8,39,,4.00E-115,O88746,Target of Myb protein 1,Target of Myb protein 1,GO:0005829; GO:0005769; GO:0006886; GO:0016020,cytosol; early endosome; intracellular protein transport; membrane,PF03127;PF00790;,3.00E-119,CHOYP_LOC101164482.1.1,,,,,,,TOM1_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886] comp140597_c0_seq1,1573,39.288,0.36612019,6,7,,4.00E-81,Q9Y140,Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),GO:0016021; GO:0016491; GO:0005778,integral to membrane; oxidoreductase activity; peroxisomal membrane,PF00106;,8.00E-33,CHOYP_LOC100114305.1.1,,,,,,,DHRS7_DROME,Drosophila melanogaster (Fruit fly), comp140597_c0_seq13,1556,39.8458,0.40814311,0,0,,3.00E-81,Q9Y140,Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),GO:0016021; GO:0016491; GO:0005778,integral to membrane; oxidoreductase activity; peroxisomal membrane,PF00106;,,,,,,,,,DHRS7_DROME,Drosophila melanogaster (Fruit fly), comp140597_c0_seq15,1607,39.079,0.39433123,0,0,,5.00E-81,Q9Y140,Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),GO:0016021; GO:0016491; GO:0005778,integral to membrane; oxidoreductase activity; peroxisomal membrane,PF00106;,8.00E-33,CHOYP_LOC100114305.1.1,,,,,,,DHRS7_DROME,Drosophila melanogaster (Fruit fly), comp140597_c0_seq20,1506,38.7782,0.25026404,14,13,,2.00E-38,Q5E9Z7,DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D),DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D),GO:0003677; GO:0005666; GO:0003899; GO:0051607; GO:0045087; GO:0045089; GO:0032728; GO:0006383,DNA binding; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; defense response to virus; innate immune response; positive regulation of innate immune response; positive regulation of interferon-beta production; transcription from RNA polymerase III promoter,PF05132;,,,,,,,,,RPC4_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription from RNA polymerase III promoter [GO:0006383] comp140597_c0_seq22,1493,38.3121,0.25915979,0,4,,2.00E-07,O74857,DNA-directed RNA polymerase III subunit rpc4 (RNA polymerase III subunit C4) (RNA polymerase III subunit C53),DNA-directed RNA polymerase III subunit rpc4 (RNA polymerase III subunit C4) (RNA polymerase III subunit C53),GO:0003677; GO:0005666; GO:0003899; GO:0005829; GO:0005634; GO:0006383,DNA binding; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; cytosol; nucleus; transcription from RNA polymerase III promoter,PF05132;,,,,,,,,,RPC4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),transcription from RNA polymerase III promoter [GO:0006383] comp140597_c0_seq23,1585,39.4322,0.39281749,0,0,,4.00E-81,Q9Y140,Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-),GO:0016021; GO:0016491; GO:0005778,integral to membrane; oxidoreductase activity; peroxisomal membrane,PF00106;,8.00E-33,CHOYP_LOC100114305.1.1,,,,,,,DHRS7_DROME,Drosophila melanogaster (Fruit fly), comp140597_c0_seq8,1603,39.8004,0.39734459,21,0,,2.00E-13,P76633,Uncharacterized oxidoreductase YgcW (EC 1.-.-.-),Uncharacterized oxidoreductase YgcW (EC 1.-.-.-),GO:0016491; GO:0006974,oxidoreductase activity; response to DNA damage stimulus,,8.00E-33,CHOYP_LOC100114305.1.1,,,,,,,YGCW_ECOLI,Escherichia coli (strain K12),cellular response to DNA damage stimulus [GO:0006974] comp140600_c1_seq1,1607,35.0342,0.44089324,84,253,,,,,,,,,2.00E-28,CHOYP_LOC100367201.2.2,,,,,,,,, comp140600_c1_seq2,1662,35.4994,0.49367122,57,488,,3.00E-26,P56812,Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19),Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19),GO:0003677; GO:0006915; GO:0005737; GO:0005634; GO:0043065,DNA binding; apoptotic process; cytoplasm; nucleus; positive regulation of apoptotic process,PF01984;,,,,,,,,,PDCD5_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chaperone-mediated protein folding [GO:1903645]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into mitochondrial outer membrane [GO:1903638]; positive regulation of release of cytochrome c from mitochondria [GO:0090200] comp140601_c0_seq1,1648,41.0801,0.55165088,45,170,,2.00E-88,Q3TUL7,DDB1- and CUL4-associated factor 17,DDB1- and CUL4-associated factor 17,GO:0080008; GO:0016021; GO:0005730; GO:0016567,Cul4-RING ubiquitin ligase complex; integral to membrane; nucleolus; protein ubiquitination,PF15802;,,,,,,,,,DCA17_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp140603_c0_seq4,2141,38.6735,0.35013084,3,0,,,,,,,,,6.00E-17,CHOYP_contig_043789,,,,,,,,, comp140603_c1_seq1,1728,35.0694,0.52860779,782,159,,5.00E-14,Q5JS54,Proteasome assembly chaperone 4 (PAC-4) (hPAC4),Proteasome assembly chaperone 4 (PAC-4) (hPAC4),,,PF16093;,,,,,,,,,PSMG4_HUMAN,Homo sapiens (Human),proteasome assembly [GO:0043248] comp140605_c0_seq1,2611,34.8142,0.47777345,295,171,,2.00E-20,Q9D7K5,ATP synthase subunit s-like protein,ATP synthase subunit s-like protein,GO:0005739,mitochondrion,,,,,,,,,,AT5SL_MOUSE,Mus musculus (Mouse), comp140605_c0_seq2,2580,34.7674,0.45857199,220,213,,2.00E-20,Q9D7K5,ATP synthase subunit s-like protein,ATP synthase subunit s-like protein,GO:0005739,mitochondrion,,,,,,,,,,AT5SL_MOUSE,Mus musculus (Mouse), comp140606_c1_seq10,1042,41.2668,1.17330557,0,0,,2.00E-07,Q60041,"Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)","Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)",GO:0031176; GO:0045493,"endo-1,4-beta-xylanase activity; xylan catabolic process",PF00331;,,,,,,,,,XYNB_THENE,Thermotoga neapolitana,xylan catabolic process [GO:0045493] comp140606_c1_seq17,948,42.2996,1.0867326,0,0,,2.00E-07,Q60041,"Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)","Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)",GO:0031176; GO:0045493,"endo-1,4-beta-xylanase activity; xylan catabolic process",PF00331;,,,3.00E-20,ruditapes_c30351,,,,,XYNB_THENE,Thermotoga neapolitana,xylan catabolic process [GO:0045493] comp140607_c0_seq3,1369,46.8955,1.07711778,20,447,,5.00E-08,Q8VY26,"Carotenoid cleavage dioxygenase 8, chloroplastic (AtCCD8) (EC 1.13.11.69) (EC 1.13.11.70) (AtNCED8) (Protein MORE AXILLARY BRANCHING 4) (Protein MORE AXILLARY GROWTH 4)","Carotenoid cleavage dioxygenase 8, chloroplastic (AtCCD8) (EC 1.13.11.69) (EC 1.13.11.70) (AtNCED8) (Protein MORE AXILLARY BRANCHING 4) (Protein MORE AXILLARY GROWTH 4)",GO:0009926; GO:0016121; GO:0009570; GO:0009965; GO:0046872; GO:0016702; GO:0009733; GO:0010223; GO:1901601; GO:0016124,"auxin polar transport; carotene catabolic process; chloroplast stroma; leaf morphogenesis; metal ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; response to auxin stimulus; secondary shoot formation; strigolactone biosynthetic process; xanthophyll catabolic process",PF03055;,,,,,,,,,CCD8_ARATH,Arabidopsis thaliana (Mouse-ear cress),auxin polar transport [GO:0009926]; carotene catabolic process [GO:0016121]; leaf morphogenesis [GO:0009965]; response to auxin [GO:0009733]; secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]; xanthophyll catabolic process [GO:0016124] comp140610_c2_seq5,2755,41.1615,1.04703304,246,1062,,6.00E-129,Q99JR5,Tubulointerstitial nephritis antigen-like (Adrenocortical zonation factor 1) (AZ-1) (Androgen-regulated gene 1 protein) (Tubulointerstitial nephritis antigen-related protein) (TARP),Tubulointerstitial nephritis antigen-like (Adrenocortical zonation factor 1) (AZ-1) (Androgen-regulated gene 1 protein) (Tubulointerstitial nephritis antigen-related protein) (TARP),GO:0008234; GO:0005737; GO:0031012; GO:0005576; GO:0006955; GO:0030247; GO:0006508; GO:0005044,cysteine-type peptidase activity; cytoplasm; extracellular matrix; extracellular region; immune response; polysaccharide binding; proteolysis; scavenger receptor activity,PF00112;,,,,,,,,,TINAL_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; immune response [GO:0006955] comp140611_c0_seq1,4139,39.164,0.51676687,3,0,,0,P57103,Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),GO:0007596; GO:0060402; GO:0005432; GO:0007154; GO:0071320; GO:0043197; GO:0016021; GO:0006811; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0042383; GO:0021537; GO:0055085,blood coagulation; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; cellular response to cAMP; dendritic spine; integral to membrane; ion transport; microtubule; mitochondrion; neuronal cell body; plasma membrane; sarcolemma; telencephalon development; transmembrane transport,PF03160;PF01699;PF16494;,5.00E-167,CHOYP_LOC100368666.1.1,,,,,,,NAC3_HUMAN,Homo sapiens (Human),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537] comp140611_c0_seq2,1940,42.3711,0.48602955,0,0,,2.00E-32,O22252,Magnesium/proton exchanger (Mg(2+)/H(+) exchanger) (AtMHX) (Zinc/proton exchanger) (Zn(2+)/H(+) exchanger),Magnesium/proton exchanger (Mg(2+)/H(+) exchanger) (AtMHX) (Zinc/proton exchanger) (Zn(2+)/H(+) exchanger),GO:0016021; GO:0006826; GO:0015693; GO:0055085; GO:0005774; GO:0006829,integral to membrane; iron ion transport; magnesium ion transport; transmembrane transport; vacuolar membrane; zinc ion transport,PF01699;,,,,,,,,,MHX_ARATH,Arabidopsis thaliana (Mouse-ear cress),ion transport [GO:0006811]; transmembrane transport [GO:0055085] comp140611_c0_seq3,1967,42.0946,0.48630678,0,0,,5.00E-11,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp140611_c0_seq4,2461,38.074,0.61854702,0,0,,7.00E-31,Q2R041,Magnesium/proton exchanger 1 (Mg(2+)/H(+) exchanger 1) (Zinc/proton exchanger 1) (Zn(2+)/H(+) exchanger 1),Magnesium/proton exchanger 1 (Mg(2+)/H(+) exchanger 1) (Zinc/proton exchanger 1) (Zn(2+)/H(+) exchanger 1),GO:0016021; GO:0006811; GO:0055085; GO:0005774,integral to membrane; ion transport; transmembrane transport; vacuolar membrane,PF01699;,3.00E-167,CHOYP_LOC100368666.1.1,,,,,,,MHX1_ORYSJ,Oryza sativa subsp. japonica (Rice),ion transport [GO:0006811]; transmembrane transport [GO:0055085] comp140611_c0_seq6,4165,39.0636,0.516497,9,9,,0,P57103,Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),GO:0007596; GO:0060402; GO:0005432; GO:0007154; GO:0071320; GO:0043197; GO:0016021; GO:0006811; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0042383; GO:0021537; GO:0055085,blood coagulation; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; cellular response to cAMP; dendritic spine; integral to membrane; ion transport; microtubule; mitochondrion; neuronal cell body; plasma membrane; sarcolemma; telencephalon development; transmembrane transport,PF03160;PF01699;PF16494;,,,,,,,,,NAC3_HUMAN,Homo sapiens (Human),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537] comp140613_c0_seq3,1949,38.2247,0.52619694,91,212,,,,,,,,,3.00E-152,CHOYP_IFT57.1.1,,,,,,,,, comp140613_c0_seq4,1990,37.8392,0.49706843,8,45,,8.00E-162,Q5EA95,Intraflagellar transport protein 57 homolog,Intraflagellar transport protein 57 homolog,GO:0003677; GO:0005794; GO:0006919; GO:0044292; GO:0005932; GO:0032391; GO:0006355; GO:0006351,"DNA binding; Golgi apparatus; activation of cysteine-type endopeptidase activity involved in apoptotic process; dendrite terminus; microtubule basal body; photoreceptor connecting cilium; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10498;,,,,,,,,,IFT57_BOVIN,Bos taurus (Bovine),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cilium assembly [GO:0042384]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; left/right pattern formation [GO:0060972]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube closure [GO:0001843]; regulation of apoptotic process [GO:0042981]; regulation of transcription, DNA-templated [GO:0006355]; smoothened signaling pathway [GO:0007224]; transcription, DNA-templated [GO:0006351]" comp140617_c0_seq1,2241,35.743,0.34963515,68,310,,,,,,,,,0,CHOYP_CSN3.1.1,,,,,,,,, comp140617_c0_seq2,2217,35.7691,0.32467771,48,158,,0,Q6P2U9,COP9 signalosome complex subunit 3 (Signalosome subunit 3),COP9 signalosome complex subunit 3 (Signalosome subunit 3),GO:0008180; GO:0005737,COP9 signalosome; cytoplasm,PF01399;,,,,,0,AM858396.p.cg.6,8,,CSN3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cullin deneddylation [GO:0010388]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140619_c0_seq4,653,42.4196,0.44452682,72,439,,4.00E-09,Q99871,HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769),HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769),GO:0070652; GO:0051301; GO:0005813; GO:0051297; GO:0005737; GO:0005874; GO:0007067; GO:0005730; GO:0005886; GO:0005819; GO:0051225; GO:0031996,HAUS complex; cell division; centrosome; centrosome organization; cytoplasm; microtubule; mitosis; nucleolus; plasma membrane; spindle; spindle assembly; thioesterase binding,,3.00E-40,CHOYP_BRAFLDRAFT_131050.1.1,,,,,,,HAUS7_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp140622_c0_seq1,2696,38.9837,0.23946906,4,0,,2.00E-08,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140622_c0_seq3,1415,38.8693,0.30573264,0,0,,3.00E-09,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp140623_c0_seq10,841,44.7087,0.47299242,25,102,,6.00E-58,Q49WS9,Uncharacterized oxidoreductase SSP1627 (EC 1.-.-.-),Uncharacterized oxidoreductase SSP1627 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF00106;,1.00E-38,CHOYP_BRAFLDRAFT_128033.2.2,,,,,,,Y1627_STAS1,Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229), comp140623_c0_seq11,2732,37.9209,0.49910373,0,0,,1.00E-55,P25145,Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA),Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,Y432_LISMO,Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e), comp140623_c0_seq2,1695,39.115,0.52619879,4,1,,2.00E-53,Q6GDV6,Uncharacterized oxidoreductase SAR2567 (EC 1.-.-.-),Uncharacterized oxidoreductase SAR2567 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,Y2567_STAAR,Staphylococcus aureus (strain MRSA252), comp140623_c0_seq3,2024,38.4881,0.72104941,0,0,,6.00E-19,Q9WVK3,"Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (PX-2,4-DCR1) (Peroxisomal 2,4-dienoyl-CoA reductase) (RLF98)","Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (PX-2,4-DCR1) (Peroxisomal 2,4-dienoyl-CoA reductase) (RLF98)",GO:0006633; GO:0005739; GO:0005778; GO:0033306; GO:0019166,fatty acid biosynthetic process; mitochondrion; peroxisomal membrane; phytol metabolic process; trans-2-enoyl-CoA reductase (NADPH) activity,,,,,,,,,,PECR_RAT,Rattus norvegicus (Rat),fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306] comp140623_c0_seq5,1684,39.2518,0.52596324,0,0,,6.00E-49,Q5HLD8,Uncharacterized oxidoreductase SERP2049 (EC 1.-.-.-),Uncharacterized oxidoreductase SERP2049 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF00106;,2.00E-20,CHOYP_BRAFLDRAFT_128033.2.2,,,,,,,Y2049_STAEQ,Staphylococcus epidermidis (strain ATCC 35984 / RP62A), comp140623_c0_seq7,2035,38.3784,0.72125659,0,0,,3.00E-56,P25145,Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA),Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,Y432_LISMO,Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e), comp140623_c0_seq9,2721,38.0007,0.49901982,0,0,,6.00E-23,Q73SC8,Uncharacterized NAD-dependent oxidoreductase MAP_4146 (EC 1.-.-.-),Uncharacterized NAD-dependent oxidoreductase MAP_4146 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,,,,,,,,,,Y4146_MYCPA,Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10), comp140624_c1_seq1,2566,35.9314,0.40147399,107,466,,1.00E-38,Q9ERU9,E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2),E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2),GO:0046907; GO:0016874; GO:0051028; GO:0005739; GO:0033132; GO:0042405; GO:0031965; GO:0044615; GO:0003755; GO:0006457; GO:0000413; GO:0016925; GO:0015031; GO:0090526; GO:0008270,intracellular transport; ligase activity; mRNA transport; mitochondrion; negative regulation of glucokinase activity; nuclear inclusion body; nuclear membrane; nuclear pore nuclear basket; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; protein sumoylation; protein transport; regulation of gluconeogenesis involved in cellular glucose homeostasis; zinc ion binding,PF12185;PF00160;PF00638;PF00641;,,,,,,,,,RBP2_MOUSE,Mus musculus (Mouse),mRNA transport [GO:0051028]; negative regulation of glucokinase activity [GO:0033132]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; response to amphetamine [GO:0001975] comp140624_c1_seq2,2476,35.5008,0.4256502,97,339,,2.00E-32,O14715,RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3),RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3),GO:0008536; GO:0005643; GO:0000042,Ran GTPase binding; nuclear pore; protein targeting to Golgi,PF01465;PF16704;PF00638;,2.00E-61,CHOYP_PHUM_PHUM477850.1.1,,,,,,,RGPD8_HUMAN,Homo sapiens (Human),protein targeting to Golgi [GO:0000042] comp140626_c1_seq1,1981,37.1025,0.90225396,13,0,,3.00E-10,Q7T3S5,"Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A (EC 2.4.1.206) (Lactotriaosylceramide synthase A) (Lc(3)Cer synthase A) (Lc3 synthase A) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A) (BGnT-5A) (Beta-1,3-Gn-T5A) (Beta-1,3-N-acetylglucosaminyltransferase 5A) (Beta3Gn-T5A)","Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A (EC 2.4.1.206) (Lactotriaosylceramide synthase A) (Lc(3)Cer synthase A) (Lc3 synthase A) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A) (BGnT-5A) (Beta-1,3-Gn-T5A) (Beta-1,3-N-acetylglucosaminyltransferase 5A) (Beta3Gn-T5A)",GO:0000139; GO:0008378; GO:0016021; GO:0047256; GO:0006486,"Golgi membrane; galactosyltransferase activity; integral to membrane; lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity; protein glycosylation",PF01762;,,,,,,,,,B3G5A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein glycosylation [GO:0006486] comp140626_c1_seq2,1593,36.221,0.75590983,0,0,,2.00E-17,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp140626_c1_seq4,1808,36.2279,0.84974285,2,0,,2.00E-17,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp140628_c0_seq1,1297,35.9291,0.43917319,66,252,,1.00E-48,Q9BSD7,Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase),Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase),GO:0005524; GO:0017111; GO:0016740,ATP binding; nucleoside-triphosphatase activity; transferase activity,PF03266;,,,3.00E-91,ruditapes_c9080,,,,,NTPCR_HUMAN,Homo sapiens (Human), comp140630_c0_seq1,2036,41.8468,0.9008294,85,540,,2.00E-27,Q7JLI1,Zinc metalloproteinase nas-31 (EC 3.4.24.21) (Nematode astacin 31),Zinc metalloproteinase nas-31 (EC 3.4.24.21) (Nematode astacin 31),GO:0005576; GO:0004222; GO:0006508; GO:0008270,extracellular region; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01400;,,,,,,,,,NAS31_CAEEL,Caenorhabditis elegans,"molting cycle, collagen and cuticulin-based cuticle [GO:0018996]" comp140632_c0_seq1,2426,38.4584,0.5845485,234,1440,,0,Q3ZC89,Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M),Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M),GO:0004177; GO:0009987; GO:0005737; GO:0046872; GO:0008235; GO:0006508,aminopeptidase activity; cellular process; cytoplasm; metal ion binding; metalloexopeptidase activity; proteolysis,PF00557;,0,CHOYP_MVP.1.1,,,,,,,AMPM2_BOVIN,Bos taurus (Bovine),protein initiator methionine removal [GO:0070084] comp140632_c0_seq2,3648,40.7895,0.60132937,1008,7627,,0,Q9ESX5,H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1),H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1),GO:0015030; GO:0003723; GO:0005730; GO:0009982; GO:0004730; GO:0000154; GO:0030519; GO:0003720; GO:0005697,Cajal body; RNA binding; nucleolus; pseudouridine synthase activity; pseudouridylate synthase activity; rRNA modification; snoRNP binding; telomerase activity; telomerase holoenzyme complex,PF08068;PF01472;PF16198;PF01509;,0,CHOYP_DKC1.1.1,6.00E-87,ruditapes_c19566,,,,,DKC1_MOUSE,Mus musculus (Mouse),box H/ACA snoRNA 3'-end processing [GO:0000495]; box H/ACA snoRNA metabolic process [GO:0033979]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; rRNA modification [GO:0000154]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120]; telomerase RNA stabilization [GO:0090669]; telomere maintenance via telomerase [GO:0007004] comp140633_c0_seq1,1702,36.4277,0.5332375,346,1013,,2.00E-21,Q2KIK3,Small integral membrane protein 14,Small integral membrane protein 14,GO:0016021,integral to membrane,PF11027;,3.00E-26,CHOYP_SMIM14.2.3,1.00E-72,ruditapes2_lrc5214,,,,,CD034_BOVIN,Bos taurus (Bovine), comp140634_c0_seq2,1162,36.9191,0.43980546,11,22,,,,,,,,,1.00E-47,CHOYP_BRAFLDRAFT_63995.1.2,,,,,,,,, comp140634_c0_seq3,1388,37.6081,0.47707036,56,160,,2.00E-75,Q9NZ63,Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59),Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59),GO:0005737; GO:0005634,cytoplasm; nucleus,PF07052;,,,,,,,,,CI078_HUMAN,Homo sapiens (Human), comp140640_c0_seq1,1564,41.4322,1.04852499,0,18,,5.00E-30,Q16527,Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (LIM domain only protein 5) (LMO-5) (Smooth muscle cell LIM protein) (SmLIM),Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (LIM domain only protein 5) (LMO-5) (Smooth muscle cell LIM protein) (SmLIM),GO:0030154; GO:0007275; GO:0005634; GO:0008270,cell differentiation; multicellular organismal development; nucleus; zinc ion binding,PF00412;,3.00E-31,CHOYP_SMP_087250.2.2,,,,,,,CSRP2_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; myoblast differentiation [GO:0045445] comp140640_c0_seq2,1627,40.3811,1.06313302,21,126,,5.00E-26,Q4U0T9,Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3),Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3),GO:0030018; GO:0060048; GO:0003300; GO:0055003; GO:0006874; GO:0005856; GO:0035995; GO:0007517; GO:0005634; GO:0033365; GO:0002026; GO:0008307; GO:0008270,Z disc; cardiac muscle contraction; cardiac muscle hypertrophy; cardiac myofibril assembly; cellular calcium ion homeostasis; cytoskeleton; detection of muscle stretch; muscle organ development; nucleus; protein localization to organelle; regulation of the force of heart contraction; structural constituent of muscle; zinc ion binding,PF00412;,,,7.00E-12,ruditapes_c14836,,,,,CSRP3_BOVIN,Bos taurus (Bovine),cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; muscle organ development [GO:0007517]; negative regulation of actin filament severing [GO:1903919]; negative regulation of myoblast differentiation [GO:0045662]; positive regulation of actin filament severing [GO:1903920]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization to organelle [GO:0033365]; regulation of the force of heart contraction [GO:0002026] comp140641_c1_seq1,2142,37.8151,0.55007499,56,255,,0,O95922,Probable tubulin polyglutamylase TTLL1 (EC 6.-.-.-) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1),Probable tubulin polyglutamylase TTLL1 (EC 6.-.-.-) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1),GO:0035083; GO:0005737; GO:0003351; GO:0005874; GO:0018095; GO:0070740,cilium axoneme assembly; cytoplasm; epithelial cilium movement; microtubule; protein polyglutamylation; tubulin-glutamic acid ligase activity,PF03133;,0,CHOYP_BRAFLDRAFT_281016.1.1,,,,,,,TTLL1_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; epithelial cilium movement [GO:0003351]; protein polyglutamylation [GO:0018095] comp140641_c1_seq6,2209,38.6148,0.47580415,22,12,,0,O95922,Probable tubulin polyglutamylase TTLL1 (EC 6.-.-.-) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1),Probable tubulin polyglutamylase TTLL1 (EC 6.-.-.-) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1),GO:0035083; GO:0005737; GO:0003351; GO:0005874; GO:0018095; GO:0070740,cilium axoneme assembly; cytoplasm; epithelial cilium movement; microtubule; protein polyglutamylation; tubulin-glutamic acid ligase activity,PF03133;,0,CHOYP_BRAFLDRAFT_281016.1.1,,,,,,,TTLL1_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; epithelial cilium movement [GO:0003351]; protein polyglutamylation [GO:0018095] comp140641_c2_seq1,1099,36.1237,1.06511132,67,298,,5.00E-50,Q5E9D6,Haloacid dehalogenase-like hydrolase domain-containing protein 3,Haloacid dehalogenase-like hydrolase domain-containing protein 3,GO:0016787; GO:0005739,hydrolase activity; mitochondrion,PF13419;,,,,,,,,,HDHD3_BOVIN,Bos taurus (Bovine),metabolic process [GO:0008152] comp140643_c0_seq1,1297,38.6276,0.46791664,135,880,,2.00E-12,Q5XK94,Translocase of inner mitochondrial membrane domain-containing protein 1,"Complex I assembly factor TIMMDC1, mitochondrial (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1)",GO:0016021,integral to membrane,PF02466;,,,,,,,,,TIDC1_XENLA,Xenopus laevis (African clawed frog), comp140645_c0_seq1,936,42.9487,0.53375829,4,4,,7.00E-100,O15488,Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186),Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186),GO:0005829; GO:0006006; GO:0005978; GO:0005980; GO:0008466; GO:0044281,cytosol; glucose metabolic process; glycogen biosynthetic process; glycogen catabolic process; glycogenin glucosyltransferase activity; small molecule metabolic process,PF01501;,,,,,,,,,GLYG2_HUMAN,Homo sapiens (Human),glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980] comp140645_c0_seq4,1701,41.0935,0.51554664,7,67,,4.00E-118,P46976,Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186),Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186),GO:0005829; GO:0005536; GO:0006006; GO:0005978; GO:0005980; GO:0008466; GO:0046872; GO:0044281,cytosol; glucose binding; glucose metabolic process; glycogen biosynthetic process; glycogen catabolic process; glycogenin glucosyltransferase activity; metal ion binding; small molecule metabolic process,PF01501;,5.00E-131,CHOYP_LOC656402.1.1,,,,,,,GLYG_HUMAN,Homo sapiens (Human),glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980] comp140645_c0_seq5,1680,40.7738,0.45856153,10,52,,7.00E-121,Q9R062,Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186),Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186),GO:0005978; GO:0008466; GO:0046872,glycogen biosynthetic process; glycogenin glucosyltransferase activity; metal ion binding,PF01501;,,,,,,,,,GLYG_MOUSE,Mus musculus (Mouse),glycogen biosynthetic process [GO:0005978] comp140645_c0_seq6,915,42.623,0.4578921,0,8,,1.00E-29,P47011,Glycogenin-2 (EC 2.4.1.186) (Glycogen synthesis initiator protein 2) (Glycogenin glucosyltransferase 2),Glycogenin-2 (EC 2.4.1.186) (Glycogen synthesis initiator protein 2) (Glycogenin glucosyltransferase 2),GO:0005737; GO:0005978; GO:0008466,cytoplasm; glycogen biosynthetic process; glycogenin glucosyltransferase activity,PF01501;,,,2.00E-78,ruditapes_c10686,,,,,GLG2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),glycogen biosynthetic process [GO:0005978] comp140647_c0_seq1,3056,34.5877,0.68996891,63,32628,female>male,8.00E-42,Q6DHB5,Lipoma HMGIC fusion partner-like 3 protein,Lipoma HMGIC fusion partner-like 3 protein,GO:0016021,integral to membrane,PF10242;,1.00E-53,CHOYP_BRAFLDRAFT_57176.5.5,,,,,,,LHPL3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140648_c0_seq2,2021,37.7041,0.50078913,2900,619,,5.00E-146,O95995,Growth arrest-specific protein 8 (GAS-8) (Growth arrest-specific protein 11) (GAS-11),Growth arrest-specific protein 8 (GAS-8) (Growth arrest-specific protein 11) (GAS-11),GO:0005794; GO:0034613; GO:0005874; GO:0005932; GO:0031514; GO:0008285; GO:0030317,Golgi apparatus; cellular protein localization; microtubule; microtubule basal body; motile cilium; negative regulation of cell proliferation; sperm motility,PF13851;,0,CHOYP_BRAFLDRAFT_263599.1.1,2.00E-152,ruditapes_c28116,,,,,GAS8_HUMAN,Homo sapiens (Human),cellular protein localization [GO:0034613]; negative regulation of cell proliferation [GO:0008285]; sperm motility [GO:0030317] comp140650_c0_seq1,1622,40.6289,0.42498847,269,1793,,8.00E-153,Q9BUI4,DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62),DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62),GO:0003677; GO:0005666; GO:0003899; GO:0005829; GO:0051607; GO:0045087; GO:0045089; GO:0032728; GO:0006359; GO:0006386; GO:0006385,DNA binding; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; cytosol; defense response to virus; innate immune response; positive regulation of innate immune response; positive regulation of interferon-beta production; regulation of transcription from RNA polymerase III promoter; termination of RNA polymerase III transcription; transcription elongation from RNA polymerase III promoter,PF08221;PF05645;,2.00E-41,CHOYP_RPC3.2.3,,,,,,,RPC3_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383] comp140657_c0_seq1,1730,37.052,0.47325577,126,561,,1.00E-22,Q9TW45,Serine/threonine-protein kinase par-1 (EC 2.7.11.1),Serine/threonine-protein kinase par-1 (EC 2.7.11.1),GO:0005524; GO:0055059; GO:0045167; GO:0005938; GO:0009880; GO:0030010; GO:0016020; GO:0046872; GO:0018105; GO:0009949; GO:0004674; GO:0040025,ATP binding; asymmetric neuroblast division; asymmetric protein localization involved in cell fate determination; cell cortex; embryonic pattern specification; establishment of cell polarity; membrane; metal ion binding; peptidyl-serine phosphorylation; polarity specification of anterior/posterior axis; protein serine/threonine kinase activity; vulval development,PF02149;PF00069;,0,CHOYP_contig_056008,,,,,,,PAR1_CAEEL,Caenorhabditis elegans,asymmetric neuroblast division [GO:0055059]; asymmetric protein localization involved in cell fate determination [GO:0045167]; embryonic pattern specification [GO:0009880]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity [GO:0007163]; peptidyl-serine phosphorylation [GO:0018105]; polarity specification of anterior/posterior axis [GO:0009949]; protein phosphorylation [GO:0006468]; vulval development [GO:0040025] comp140657_c0_seq2,1535,38.1107,0.48548438,6,83,,7.00E-65,Q14004,Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller),Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller),GO:0005524; GO:0008353; GO:0000380; GO:0002945; GO:0004693; GO:0030097; GO:0019048; GO:0019908; GO:0016607; GO:0070816; GO:0008284; GO:0007088,"ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; alternative mRNA splicing, via spliceosome; cyclin K-CDK13 complex; cyclin-dependent protein serine/threonine kinase activity; hemopoiesis; modulation by virus of host morphology or physiology; nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; phosphorylation of RNA polymerase II C-terminal domain; positive regulation of cell proliferation; regulation of mitosis",PF00069;,8.00E-20,CHOYP_CDK5.1.1,,,,,,,CDK13_HUMAN,Homo sapiens (Human),"alternative mRNA splicing, via spliceosome [GO:0000380]; hemopoiesis [GO:0030097]; multicellular organism development [GO:0007275]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cell proliferation [GO:0008284]; regulation of mitotic nuclear division [GO:0007088]; viral process [GO:0016032]" comp140657_c0_seq3,1762,37.2304,0.52521546,75,387,,3.00E-173,P51958,Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase),Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase),GO:0005524; GO:0008353; GO:0051301; GO:0004693; GO:0005737; GO:0005815; GO:0007067; GO:0005634,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cell division; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; microtubule organizing center; mitosis; nucleus,PF00069;,0,CHOYP_contig_056008,,,,,,,CDK1_CARAU,Carassius auratus (Goldfish),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp140659_c0_seq2,1843,38.3071,1.02374412,6,9,,1.00E-10,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp140659_c0_seq7,699,46.6381,0.95454741,0,0,,4.00E-09,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp140660_c0_seq4,667,42.7286,0.62565457,7,13,,3.00E-23,Q0P4M4,Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),GO:0005829; GO:0004181; GO:0006508; GO:0008270,cytosol; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,8.00E-47,CHOYP_LOC580601.1.5,,,,,,,CBPC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein side chain deglutamylation [GO:0035610] comp140665_c0_seq1,1658,39.2642,0.68896674,80,261,,1.00E-99,Q5ZJ87,Probable methyltransferase BTM2 homolog (EC 2.1.1.-),Probable methyltransferase BTM2 homolog (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF11968;,,,,,,,,,CG060_CHICK,Gallus gallus (Chicken), comp140666_c0_seq3,825,39.2727,0.63239384,5,84,,2.00E-21,Q91WL8,WW domain-containing oxidoreductase (EC 1.1.1.-),WW domain-containing oxidoreductase (EC 1.1.1.-),GO:0005794; GO:0016055; GO:0071560; GO:0005829; GO:0097191; GO:0072332; GO:0005902; GO:0005739; GO:0030178; GO:0005634; GO:0001649; GO:0016491; GO:0005886; GO:2001241; GO:0045944; GO:0048705,Golgi apparatus; Wnt receptor signaling pathway; cellular response to transforming growth factor beta stimulus; cytosol; extrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway by p53 class mediator; microvillus; mitochondrion; negative regulation of Wnt receptor signaling pathway; nucleus; osteoblast differentiation; oxidoreductase activity; plasma membrane; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of transcription from RNA polymerase II promoter; skeletal system morphogenesis,PF00106;PF00397;,5.00E-13,CHOYP_LOC763133.3.3,,,,,,,WWOX_MOUSE,Mus musculus (Mouse),cellular response to transforming growth factor beta stimulus [GO:0071560]; extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055] comp140666_c0_seq4,825,40,0.63722955,0,12,,1.00E-23,Q9ERI6,Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2),Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2),GO:0005783; GO:0005739; GO:0016491,endoplasmic reticulum; mitochondrion; oxidoreductase activity,PF00106;,,,,,,,,,RDH14_MOUSE,Mus musculus (Mouse),osteoblast differentiation [GO:0001649]; retinol metabolic process [GO:0042572] comp140668_c0_seq1,2080,42.5,0.50222726,5,25,,0,Q863I2,Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein),Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein),GO:0005524; GO:0005737; GO:0007243; GO:0000287; GO:0004674,ATP binding; cytoplasm; intracellular protein kinase cascade; magnesium ion binding; protein serine/threonine kinase activity,PF12202;PF00069;,,,,,,,,,OXSR1_PIG,Sus scrofa (Pig),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp140668_c0_seq2,2026,42.4482,0.49399604,31,6,,0,Q863I2,Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein),Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein),GO:0005524; GO:0005737; GO:0007243; GO:0000287; GO:0004674,ATP binding; cytoplasm; intracellular protein kinase cascade; magnesium ion binding; protein serine/threonine kinase activity,PF12202;PF00069;,0,CHOYP_PAXB1.1.2,,,,,,,OXSR1_PIG,Sus scrofa (Pig),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp140668_c0_seq3,233,42.4893,0.20190191,5,1,,,,,,,,,2.00E-23,CHOYP_ISCW_ISCW022925.2.2,,,,,,,,, comp140670_c1_seq1,2921,41.6638,0.52033342,97,306,,5.00E-108,Q5ZJ85,U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3),U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3),GO:0046540; GO:0000398; GO:0016607; GO:0005681,"U4/U6 x U5 tri-snRNP complex; mRNA splicing, via spliceosome; nuclear speck; spliceosomal complex",PF06544;PF08572;PF01480;,2.00E-126,CHOYP_PRPF3.1.1,,,,,,,PRPF3_CHICK,Gallus gallus (Chicken),"mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp140670_c1_seq2,1573,38.9701,0.7312673,4,57,,6.00E-99,Q922U1,U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3),U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3),GO:0015030; GO:0046540; GO:0005737; GO:0000398; GO:0016607; GO:0005681,"Cajal body; U4/U6 x U5 tri-snRNP complex; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; spliceosomal complex",PF06544;PF08572;PF01480;,,,,,,,,,PRPF3_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp140672_c0_seq1,2233,39.4536,0.55704823,5815,25018,,9.00E-15,Q4J781,NAD-dependent alcohol dehydrogenase (EC 1.1.1.1),NAD-dependent alcohol dehydrogenase (EC 1.1.1.1),GO:0004022; GO:0008270,alcohol dehydrogenase (NAD) activity; zinc ion binding,PF08240;PF00107;,8.00E-66,CHOYP_LOC408643.1.1,2.00E-27,ruditapes2_c52,,,,,ADH_SULAC,Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770), comp140673_c0_seq2,996,36.8474,0.38733528,15,55,,4.00E-19,Q5I0X7,Tetratricopeptide repeat protein 32 (TPR repeat protein 32),Tetratricopeptide repeat protein 32 (TPR repeat protein 32),,,PF00515;,,,,,,,,,TTC32_HUMAN,Homo sapiens (Human), comp140675_c1_seq3,923,41.8202,0.55924575,81,236,,2.00E-60,Q5ZKJ4,FGFR1 oncogene partner 2 homolog,FGFR1 oncogene partner 2 homolog,GO:0005737; GO:0042060,cytoplasm; wound healing,PF05769;,2.00E-49,CHOYP_LOC100010019.1.1,,,,,,,FGOP2_CHICK,Gallus gallus (Chicken),wound healing [GO:0042060] comp140677_c0_seq1,1197,41.7711,0.25008448,2,17,,3.00E-37,Q2UDB2,RNA polymerase II holoenzyme cyclin-like subunit,RNA polymerase II holoenzyme cyclin-like subunit,GO:0016591; GO:0016538; GO:0016592; GO:0000079; GO:0006355; GO:0006351,"DNA-directed RNA polymerase II, holoenzyme; cyclin-dependent protein serine/threonine kinase regulator activity; mediator complex; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00134;,,,,,,,,,SSN8_ASPOR,Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140677_c0_seq2,1210,41.6529,0.24903916,16,75,,2.00E-140,Q7QB13,Cyclin-C,Cyclin-C,GO:0016591; GO:0000079; GO:0006355; GO:0006351,"DNA-directed RNA polymerase II, holoenzyme; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16899;PF00134;,2.00E-126,CHOYP_CCNC.1.1,3.00E-34,ruditapes_c11913,,,,,CCNC_ANOGA,Anopheles gambiae (African malaria mosquito),"positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140680_c1_seq1,2006,43.4696,0.49966727,80,224,,0,Q6PAX2,ATPase family AAA domain-containing protein 3-B,ATPase family AAA domain-containing protein 3-B,GO:0005524; GO:0016021; GO:0005743; GO:0042645; GO:0017111,ATP binding; integral to membrane; mitochondrial inner membrane; mitochondrial nucleoid; nucleoside-triphosphatase activity,PF00004;PF12037;,0,CHOYP_LOC101065695.1.1,,,,,,,ATD3B_XENLA,Xenopus laevis (African clawed frog), comp140681_c0_seq3,854,43.4426,0.83220383,33,320,,8.00E-31,Q24372,Lachesin,Lachesin,GO:0031225; GO:0061343; GO:0007156; GO:0035160; GO:0016331; GO:0005886; GO:0042803; GO:0035151; GO:0005918; GO:0019991,"anchored to membrane; cell adhesion involved in heart morphogenesis; homophilic cell adhesion; maintenance of epithelial integrity, open tracheal system; morphogenesis of embryonic epithelium; plasma membrane; protein homodimerization activity; regulation of tube size, open tracheal system; septate junction; septate junction assembly",PF07679;,,,,,,,,,LACH_DROME,Drosophila melanogaster (Fruit fly),"cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]" comp140683_c0_seq1,2978,39.0195,0.50791781,4858,27620,,0,Q4R6V2,T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon),T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon),GO:0005524; GO:0005737; GO:0005815; GO:0006457,ATP binding; cytoplasm; microtubule organizing center; protein folding,PF00118;,0,CHOYP_BRAFLDRAFT_124069.1.1,9.00E-27,ruditapes_c7262,,,,,TCPE_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein folding [GO:0006457] comp140684_c0_seq1,3436,45.4016,0.44903663,34,26,,2.00E-180,P48053,Uncharacterized protein C05D11.1,Uncharacterized protein C05D11.1,GO:0003824; GO:0008152; GO:0046872,catalytic activity; metabolic process; metal ion binding,PF00675;PF05193;,,,,,,,,,YPD1_CAEEL,Caenorhabditis elegans,protein processing [GO:0016485] comp140684_c0_seq2,3449,45.3465,0.44841836,53,116,,2.00E-180,P48053,Uncharacterized protein C05D11.1,Uncharacterized protein C05D11.1,GO:0003824; GO:0008152; GO:0046872,catalytic activity; metabolic process; metal ion binding,PF00675;PF05193;,,,,,,,,,YPD1_CAEEL,Caenorhabditis elegans,protein processing [GO:0016485] comp140685_c0_seq2,1338,34.4544,0.50577954,3,63,,4.00E-41,A7MCB7,Translation machinery-associated protein 16,Translation machinery-associated protein 16,,,PF11176;,,,5.00E-26,ruditapes_c7617,,,,,TMA16_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140689_c0_seq2,2730,41.4286,0.62350025,1299,9371,,0,Q561P5,DNA replication licensing factor mcm5 (EC 3.6.4.12),DNA replication licensing factor mcm5 (EC 3.6.4.12),GO:0005524; GO:0006200; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0000785; GO:0005634; GO:0030174,ATP binding; ATP catabolic process; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; chromatin; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF14551;,0,CHOYP_MCM5.1.1,2.00E-105,ruditapes_c24251,7.00E-119,CU990820.p.cg.6,9,,MCM5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chordate embryonic development [GO:0043009]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle [GO:0000278]; negative regulation of apoptotic process [GO:0043066]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp140689_c0_seq3,1676,44.2721,0.62695747,29,202,,0,P55862,DNA replication licensing factor mcm5-A (xMCM5-A) (EC 3.6.4.12) (CDC46 homolog A) (xCDC46-A) (CDC46p) (p92),DNA replication licensing factor mcm5-A (xMCM5-A) (EC 3.6.4.12) (CDC46 homolog A) (xCDC46-A) (CDC46p) (p92),GO:0005524; GO:0006200; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0000785; GO:0005634; GO:0030174,ATP binding; ATP catabolic process; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; chromatin; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF14551;,2.00E-21,CHOYP_MCM7.1.1,,,,,,,MCM5A_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp14068_c0_seq1,230,40,0.54818312,0,6,,1.00E-13,Q91ZG2,Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-),Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-),GO:0016787,hydrolase activity,PF00149;,,,,,,,,,MPPD1_MOUSE,Mus musculus (Mouse), comp140690_c4_seq1,1697,36.1226,0.38031157,94,726,,1.00E-127,Q7SXW4,ER membrane protein complex subunit 3 (Protein pob) (Transmembrane protein 111),ER membrane protein complex subunit 3 (Protein pob) (Transmembrane protein 111),GO:0072546; GO:0045494; GO:0060041; GO:0030140,ER membrane protein complex; photoreceptor cell maintenance; retina development in camera-type eye; trans-Golgi network transport vesicle,PF01956;,2.00E-117,CHOYP_BRAFLDRAFT_126946.1.1,2.00E-151,ruditapes_c21234,,,,,EMC3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),photoreceptor cell maintenance [GO:0045494]; protein folding in endoplasmic reticulum [GO:0034975]; retina development in camera-type eye [GO:0060041] comp140692_c1_seq1,2714,36.0722,0.5100595,0,0,,3.00E-74,Q6BT27,ATP-dependent RNA helicase FAL1 (EC 3.6.4.13),ATP-dependent RNA helicase FAL1 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF00271;,1.00E-96,CHOYP_DD19A.1.1,,,,,,,FAL1_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp140692_c1_seq2,2792,36.1032,0.50569331,0,0,,0,Q3ZBV2,ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A),ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0051028; GO:0031965; GO:0005643; GO:0015031,ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; mRNA transport; nuclear membrane; nuclear pore; protein transport,PF00270;PF00271;,,,,,,,,,DD19A_BOVIN,Bos taurus (Bovine),mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501] comp140692_c1_seq3,727,42.0908,0.37731683,0,0,,6.00E-10,A7TNT1,ATP-dependent RNA helicase DBP7 (EC 3.6.4.13),ATP-dependent RNA helicase DBP7 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF13959;PF00271;,,,,,,,,,DBP7_VANPO,Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus),"maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit assembly [GO:0000027]" comp140692_c1_seq4,1586,39.9748,0.53794974,0,0,,9.00E-167,Q9UHL0,ATP-dependent RNA helicase DDX25 (EC 3.6.4.13) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase),ATP-dependent RNA helicase DDX25 (EC 3.6.4.13) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase),GO:0005524; GO:0004004; GO:0003723; GO:0033391; GO:0006406; GO:0007275; GO:0005634; GO:0006417; GO:0007286,ATP binding; ATP-dependent RNA helicase activity; RNA binding; chromatoid body; mRNA export from nucleus; multicellular organismal development; nucleus; regulation of translation; spermatid development,PF00270;PF00271;,,,,,,,,,DDX25_HUMAN,Homo sapiens (Human),mRNA export from nucleus [GO:0006406]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]; spermatid development [GO:0007286] comp140692_c1_seq5,3047,37.5123,0.48372527,0,0,,7.00E-120,Q75C39,ATP-dependent RNA helicase DBP5 (EC 3.6.4.13),ATP-dependent RNA helicase DBP5 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0051028; GO:0031965; GO:0005643; GO:0015031,ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; mRNA transport; nuclear membrane; nuclear pore; protein transport,PF00270;PF00271;,,,,,,,,,DBP5_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501]; translational termination [GO:0006415] comp140692_c1_seq6,1841,41.7708,0.49587921,0,0,,0,Q3ZBV2,ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A),ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0051028; GO:0031965; GO:0005643; GO:0015031,ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; mRNA transport; nuclear membrane; nuclear pore; protein transport,PF00270;PF00271;,8.00E-122,CHOYP_DD19A.1.1,,,,,,,DD19A_BOVIN,Bos taurus (Bovine),mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501] comp140692_c1_seq7,982,44.9084,0.36550337,0,0,,9.00E-13,Q754J2,ATP-dependent RNA helicase DBP7 (EC 3.6.4.13),ATP-dependent RNA helicase DBP7 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF13959;PF00271;,,,,,,,,,DBP7_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),"maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit assembly [GO:0000027]; RNA secondary structure unwinding [GO:0010501]" comp140692_c1_seq8,2969,37.5211,0.48678156,0,0,,2.00E-130,Q09747,ATP-dependent RNA helicase dbp5 (EC 3.6.4.13),ATP-dependent RNA helicase dbp5 (EC 3.6.4.13),GO:0005524; GO:0004004; GO:0003723; GO:0002184; GO:0005829; GO:0006406; GO:0005635; GO:0031965; GO:0005643; GO:0015031,ATP binding; ATP-dependent RNA helicase activity; RNA binding; cytoplasmic translational termination; cytosol; mRNA export from nucleus; nuclear envelope; nuclear membrane; nuclear pore; protein transport,PF00270;PF00271;,,,,,,,,,DBP5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translational termination [GO:0002184]; mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501] comp140693_c1_seq1,1176,34.6088,0.43159959,154,1452,,7.00E-42,Q9D2P4,Ubiquitin-related modifier 1,Ubiquitin-related modifier 1,GO:0005737; GO:0034227; GO:0002098,cytoplasm; tRNA thio-modification; tRNA wobble uridine modification,PF09138;,,,,,,,,,URM1_MOUSE,Mus musculus (Mouse),protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] comp140695_c0_seq1,2928,40.403,0.31914778,441,1266,,4.00E-20,Q5ZM33,Heterochromatin protein 1-binding protein 3,Heterochromatin protein 1-binding protein 3,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00538;,,,,,,,,,HP1B3_CHICK,Gallus gallus (Chicken),"heterochromatin organization [GO:0070828]; nucleosome assembly [GO:0006334]; regulation of transcription, DNA-templated [GO:0006355]" comp140697_c0_seq1,2855,42.2417,0.49288947,0,0,,7.00E-92,Q8AV28,Pericentriolar material 1 protein (PCM-1),Pericentriolar material 1 protein (PCM-1),GO:0034451; GO:0042384,centriolar satellite; cilium assembly,PF15717;,2.00E-55,CHOYP_LOC581113.2.2,,,,,,,PCM1_CHICK,Gallus gallus (Chicken),centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp140697_c0_seq2,749,48.0641,0.62656753,0,0,,,,,,,,,,,3.00E-38,ruditapes_c20886,,,,,,, comp140697_c0_seq3,2867,42.1695,0.49256789,0,0,,1.00E-90,Q8AV28,Pericentriolar material 1 protein (PCM-1),Pericentriolar material 1 protein (PCM-1),GO:0034451; GO:0042384,centriolar satellite; cilium assembly,PF15717;,6.00E-50,CHOYP_LOC581113.2.2,,,,,,,PCM1_CHICK,Gallus gallus (Chicken),centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp140698_c0_seq2,3359,45.0432,0.43943929,6,0,,2.00E-85,O88974,Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1),Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1),GO:0003677; GO:0060348; GO:0005694; GO:0018024; GO:0001833; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; bone development; chromosome; histone-lysine N-methyltransferase activity; inner cell mass cell proliferation; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01429;PF05033;PF00856;,6.00E-89,CHOYP_LOC100372058.2.2,,,,,,,SETB1_MOUSE,Mus musculus (Mouse),"bone development [GO:0060348]; histone H3-K9 trimethylation [GO:0036124]; inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]" comp140698_c0_seq3,2597,45.129,0.4585853,0,0,,4.00E-85,O88974,Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1),Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1),GO:0003677; GO:0060348; GO:0005694; GO:0018024; GO:0001833; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; bone development; chromosome; histone-lysine N-methyltransferase activity; inner cell mass cell proliferation; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01429;PF05033;PF00856;,4.00E-89,CHOYP_LOC100372058.2.2,,,,,,,SETB1_MOUSE,Mus musculus (Mouse),"bone development [GO:0060348]; histone H3-K9 trimethylation [GO:0036124]; inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]" comp140698_c0_seq4,2714,44.9521,0.44762753,0,0,,,,,,,,,2.00E-87,CHOYP_LOC100863269.1.1,,,,,,,,, comp140701_c4_seq1,356,35.1124,1.10016276,47,43,,6.00E-13,P52899,"Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)","Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)",GO:0006096; GO:0005759; GO:0005739; GO:0004739,glycolysis; mitochondrial matrix; mitochondrion; pyruvate dehydrogenase (acetyl-transferring) activity,PF00676;,,,,,,,,,ODPA_CAEEL,Caenorhabditis elegans,acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] comp140702_c1_seq1,3279,36.383,0.28873898,6104,774,,3.00E-11,P08220,Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1),Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1),GO:0004890; GO:0030054; GO:0005254; GO:0034707; GO:0005230; GO:0045211,GABA-A receptor activity; cell junction; chloride channel activity; chloride channel complex; extracellular ligand-gated ion channel activity; postsynaptic membrane,PF02931;PF02932;,2.00E-82,CHOYP_BRAFLDRAFT_64442.2.2,,,,,,,GBRB1_BOVIN,Bos taurus (Bovine),cellular response to histamine [GO:0071420]; ion transport [GO:0006811] comp140705_c1_seq1,1330,45.4887,0.38376937,356,278,,3.00E-129,Q8VDM6,Heterogeneous nuclear ribonucleoprotein U-like protein 1,Heterogeneous nuclear ribonucleoprotein U-like protein 1,GO:0003723; GO:0005634; GO:0006355; GO:0030529; GO:0006351,"RNA binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF02037;PF00622;,1.00E-79,CHOYP_LOC100553519.1.1,,,,,,,HNRL1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; response to virus [GO:0009615]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]" comp140706_c0_seq1,2459,42.1309,0.49066141,5186,31542,,0,Q6P502,T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma),T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma),GO:0005524; GO:0005737; GO:0006457,ATP binding; cytoplasm; protein folding,PF00118;,0,CHOYP_LOC100372926.1.3,3.00E-88,ruditapes_c8145,,,,,TCPG_RAT,Rattus norvegicus (Rat),binding of sperm to zona pellucida [GO:0007339]; pore complex assembly [GO:0046931]; protein folding [GO:0006457]; toxin transport [GO:1901998] comp140707_c2_seq1,996,48.1928,0.44777639,25,33,,5.00E-24,Q5UQ96,Putative ATP-dependent RNA helicase L540 (EC 3.6.4.13),Putative ATP-dependent RNA helicase L540 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003676; GO:0019012,ATP binding; ATP-dependent helicase activity; nucleic acid binding; virion,PF00270;PF04408;PF00271;,7.00E-31,CHOYP_PRP16.1.1,,,,,,,YL540_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp140707_c3_seq1,1793,42.7775,0.34171439,54,227,,0,Q767K6,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (DEAH-box protein 16),Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (DEAH-box protein 16),GO:0005524; GO:0008026; GO:0008380; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; mRNA processing; nucleic acid binding; nucleus,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_LOC100375367.1.1,,,3.00E-122,AM862862.p.cg.6,7,,DHX16_PIG,Sus scrofa (Pig),"mRNA splicing, via spliceosome [GO:0000398]" comp140710_c1_seq1,1772,38.0926,0.50275603,23,118,,2.00E-63,Q9DB94,WD repeat-containing protein 53,WD repeat-containing protein 53,,,PF00400;,4.00E-30,CHOYP_NEMVEDRAFT_V1G244670.1.1,,,,,,,WDR53_MOUSE,Mus musculus (Mouse), comp140710_c1_seq2,1354,37.8139,0.55968639,0,4,,2.00E-06,Q9UUG8,Transcriptional repressor tup12,Transcriptional repressor tup12,GO:0043156; GO:0006342; GO:0005829; GO:0042393; GO:0045014; GO:0000122; GO:0000790; GO:0043234; GO:0003714; GO:0006351,"chromatin remodeling in response to cation stress; chromatin silencing; cytosol; histone binding; negative regulation of transcription by glucose; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein complex; transcription corepressor activity; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP12_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling in response to cation stress [GO:0043156]; chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp140714_c0_seq2,1502,40.0133,0.63759487,188,663,,1.00E-128,Q2KID0,Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4),Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4),GO:0003723; GO:0005737; GO:0000178; GO:0005730; GO:0030307; GO:0006364,RNA binding; cytoplasm; exosome (RNase complex); nucleolus; positive regulation of cell growth; rRNA processing,PF14382;PF15985;,1.00E-87,CHOYP_EXOSC2.1.1,,,,,,,EXOS2_BOVIN,Bos taurus (Bovine),"CUT catabolic process [GO:0071034]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; U4 snRNA 3'-end processing [GO:0034475]" comp140715_c0_seq1,2814,32.1251,0.64369093,0,0,,6.00E-114,P01122,Ras-like GTP-binding protein RHO,Ras-like GTP-binding protein RHO,GO:0005525; GO:0005622; GO:0005886; GO:0007264,GTP binding; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,3.00E-110,CHOYP_RHO.1.1,,,,,,,RHO_APLCA,Aplysia californica (California sea hare),small GTPase mediated signal transduction [GO:0007264] comp140715_c0_seq2,2827,32.4018,0.6569488,7,84,,2.00E-107,P22122,Ras-like GTP-binding protein O-RHO,Ras-like GTP-binding protein O-RHO,GO:0005525; GO:0005622; GO:0005886; GO:0007264,GTP binding; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RHO_DISOM,Diplobatis ommata (Ocellated electric ray) (Discopyge ommata),small GTPase mediated signal transduction [GO:0007264] comp140715_c0_seq3,2258,35.0753,0.64104958,500,659,,8.00E-120,P01122,Ras-like GTP-binding protein RHO,Ras-like GTP-binding protein RHO,GO:0005525; GO:0005622; GO:0005886; GO:0007264,GTP binding; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,4.00E-121,CHOYP_RHO.1.1,1.00E-150,ruditapes_c9632,,,,,RHO_APLCA,Aplysia californica (California sea hare),small GTPase mediated signal transduction [GO:0007264] comp140715_c0_seq4,2778,32.0374,0.66943615,0,0,,1.00E-46,Q9Z1Y0,Rho-related GTP-binding protein RhoV (Rho family GTPase Chp),Rho-related GTP-binding protein RhoV (Rho family GTPase Chp),GO:0005525; GO:0010008; GO:0046872; GO:0005886; GO:0007165; GO:0007264,GTP binding; endosome membrane; metal ion binding; plasma membrane; signal transduction; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RHOV_RAT,Rattus norvegicus (Rat),signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] comp140715_c0_seq5,1820,32.3626,0.73823173,2,92,,8.00E-14,Q9LS94,Ras-related protein RABG3f (AtRABG3f) (Ras-related protein Rab71) (AtRab71) (Ras-related protein Rab7B) (AtRab7B),Ras-related protein RABG3f (AtRABG3f) (Ras-related protein Rab71) (AtRab71) (Ras-related protein Rab7B) (AtRab7B),GO:0005525; GO:0005794; GO:0005634; GO:0005886; GO:0015031; GO:0007264,GTP binding; Golgi apparatus; nucleus; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,2.00E-46,CHOYP_AAEL_AAEL013139.2.2,,,,,,,RAG3F_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp140715_c0_seq6,2815,31.9005,0.6550262,0,0,,2.00E-113,Q5RCK9,Rho-related GTP-binding protein RhoC,Rho-related GTP-binding protein RhoC,GO:0005525; GO:0043297; GO:0032154; GO:0000910; GO:0005622; GO:0005886; GO:0007264,GTP binding; apical junction assembly; cleavage furrow; cytokinesis; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RHOC_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"apical junction assembly [GO:0043297]; cytokinesis [GO:0000910]; skeletal muscle satellite cell migration [GO:1902766]; small GTPase mediated signal transduction [GO:0007264]; wound healing, spreading of cells [GO:0044319]" comp140715_c0_seq7,2791,31.9957,0.6685484,0,0,,1.00E-17,Q504M8,Ras-related protein Rab-26,Ras-related protein Rab-26,GO:0019002; GO:0005525; GO:0000139; GO:0043001; GO:0035272; GO:0031226; GO:0045055; GO:0017157; GO:0030667; GO:0007264; GO:0030658,GMP binding; GTP binding; Golgi membrane; Golgi to plasma membrane protein transport; exocrine system development; intrinsic to plasma membrane; regulated secretory pathway; regulation of exocytosis; secretory granule membrane; small GTPase mediated signal transduction; transport vesicle membrane,PF00071;,2.00E-101,CHOYP_LOC101071942.1.1,,,,,,,RAB26_MOUSE,Mus musculus (Mouse),exocrine system development [GO:0035272]; Golgi to plasma membrane protein transport [GO:0043001]; regulated exocytosis [GO:0045055]; regulation of exocytosis [GO:0017157]; small GTPase mediated signal transduction [GO:0007264] comp140715_c0_seq8,2802,31.9415,0.65585269,0,0,,6.00E-114,P01122,Ras-like GTP-binding protein RHO,Ras-like GTP-binding protein RHO,GO:0005525; GO:0005622; GO:0005886; GO:0007264,GTP binding; intracellular; plasma membrane; small GTPase mediated signal transduction,PF00071;,3.00E-110,CHOYP_RHO.1.1,1.00E-31,ruditapes_c20613,,,,,RHO_APLCA,Aplysia californica (California sea hare),small GTPase mediated signal transduction [GO:0007264] comp140716_c1_seq1,2668,37.2189,0.58918331,396,989,,9.00E-23,F6SNN2,DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP),DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP),GO:0003677; GO:0051301; GO:0000724; GO:0004519; GO:0007126; GO:0007067; GO:0090305; GO:0005634,DNA binding; cell division; double-strand break repair via homologous recombination; endonuclease activity; meiosis; mitosis; nucleic acid phosphodiester bond hydrolysis; nucleus,PF10482;PF08573;,,,,,,,,,COM1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; DNA damage checkpoint [GO:0000077]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067] comp140718_c0_seq1,2083,35.6697,0.53100579,264,1236,,8.00E-11,P39598,Uncharacterized protein YwbO,Uncharacterized protein YwbO,GO:0015035,protein disulfide oxidoreductase activity,PF01323;,1.00E-13,CHOYP_LOC100375622.1.1,5.00E-66,ruditapes2_c1833,,,,,YWBO_BACSU,Bacillus subtilis (strain 168), comp140719_c0_seq5,965,39.4819,0.48033201,34,3,,,,,,,,,8.00E-68,CHOYP_BRAFLDRAFT_89535.1.1,9.00E-78,ruditapes_c9789,,,,,,, comp140719_c0_seq6,999,38.9389,0.55673439,49,8,,2.00E-89,Q8C4B4,Protein unc-119 homolog B,Protein unc-119 homolog B,GO:0035869; GO:0060271; GO:0008289; GO:0042953,ciliary transition zone; cilium morphogenesis; lipid binding; lipoprotein transport,PF05351;,,,,,,,,,U119B_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; lipoprotein transport [GO:0042953] comp140720_c1_seq1,1164,36.1684,0.27153665,23,456,,3.00E-51,P47957,Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7),Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7),GO:0044209; GO:0003999; GO:0006168; GO:0005737; GO:0006166,AMP salvage; adenine phosphoribosyltransferase activity; adenine salvage; cytoplasm; purine ribonucleoside salvage,PF00156;,4.00E-16,CHOYP_LOC583890.1.1,,,,,,,APT_MUSSI,Mus spicilegus (Steppe mouse),adenine salvage [GO:0006168]; AMP salvage [GO:0044209] comp140720_c1_seq2,949,35.3003,0.10635928,13,110,,2.00E-07,D2RXU5,HGPRTase-like protein 1 (EC 2.4.2.-),HGPRTase-like protein 1 (EC 2.4.2.-),GO:0006166; GO:0016740,purine ribonucleoside salvage; transferase activity,PF00156;,,,,,,,,,HPRL1_HALTV,Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (Halococcus turkmenicus),purine ribonucleoside salvage [GO:0006166] comp140721_c0_seq1,2600,40.8077,0.39104387,62,23,,0,Q8NFJ9,Bardet-Biedl syndrome 1 protein (BBS2-like protein 2),Bardet-Biedl syndrome 1 protein (BBS2-like protein 2),GO:0034464; GO:0043001; GO:0060170; GO:0005737; GO:0005815; GO:0035058; GO:0045494; GO:0050896; GO:0007601,BBSome; Golgi to plasma membrane protein transport; cilium membrane; cytoplasm; microtubule organizing center; nonmotile primary cilium assembly; photoreceptor cell maintenance; response to stimulus; visual perception,PF14779;,0,CHOYP_LOC100369017.1.1,,,,,,,BBS1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; Golgi to plasma membrane protein transport [GO:0043001]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; protein localization to cilium [GO:0061512]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; visual perception [GO:0007601] comp140721_c0_seq3,2324,41.3081,0.37585369,4,9,,0,Q8NFJ9,Bardet-Biedl syndrome 1 protein (BBS2-like protein 2),Bardet-Biedl syndrome 1 protein (BBS2-like protein 2),GO:0034464; GO:0043001; GO:0060170; GO:0005737; GO:0005815; GO:0035058; GO:0045494; GO:0050896; GO:0007601,BBSome; Golgi to plasma membrane protein transport; cilium membrane; cytoplasm; microtubule organizing center; nonmotile primary cilium assembly; photoreceptor cell maintenance; response to stimulus; visual perception,PF14779;,0,CHOYP_LOC100369017.1.1,,,,,,,BBS1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; Golgi to plasma membrane protein transport [GO:0043001]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; protein localization to cilium [GO:0061512]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; visual perception [GO:0007601] comp140725_c0_seq1,3657,41.154,0.62204938,3983,13,male>female,5.00E-163,A4Q9E5,Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 3),Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 3),GO:0035082; GO:0042384; GO:0035085; GO:0005874; GO:0015630; GO:0018094; GO:0070736,"axoneme assembly; cilium assembly; cilium axoneme; microtubule; microtubule cytoskeleton; protein polyglycylation; protein-glycine ligase activity, initiating",PF03133;,6.00E-159,CHOYP_LOC578867.3.5,,,,,,,TTLL3_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; protein polyglycylation [GO:0018094] comp140726_c0_seq1,2635,36.7742,0.43491179,111,710,,,,,,,,,1.00E-82,CHOYP_DCTN2.1.1,,,,,,,,, comp140726_c0_seq2,2546,36.685,0.45123999,6,44,,2.00E-111,Q6IRB3,Dynactin subunit 2-B,Dynactin subunit 2-B,GO:0005737; GO:0005869; GO:0030286; GO:0016020; GO:0005874; GO:0005815; GO:0007017; GO:0007067; GO:0003774; GO:0031982,cytoplasm; dynactin complex; dynein complex; membrane; microtubule; microtubule organizing center; microtubule-based process; mitosis; motor activity; vesicle,,1.00E-82,CHOYP_DCTN2.1.1,,,,,,,DCT2B_XENLA,Xenopus laevis (African clawed frog),microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067] comp140728_c0_seq1,2999,41.0137,0.93931953,235,682,,2.00E-166,Q9R087,Glypican-6 [Cleaved into: Secreted glypican-6],Glypican-6 [Cleaved into: Secreted glypican-6],GO:0005796; GO:0031225; GO:0016477; GO:0005615; GO:0005887; GO:0005578,Golgi lumen; anchored to membrane; cell migration; extracellular space; integral to plasma membrane; proteinaceous extracellular matrix,PF01153;,5.00E-76,CHOYP_GPC6.1.1,,,,,,,GPC6_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024] comp140730_c0_seq2,3569,38.9745,0.46585476,122,2818,,5.00E-145,Q5RBM1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2),GO:0016021; GO:0008250; GO:0006487; GO:0016757,"integral to membrane; oligosaccharyltransferase complex; protein N-linked glycosylation; transferase activity, transferring glycosyl groups",PF05817;,,,,,,,,,RPN2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein N-linked glycosylation [GO:0006487] comp140730_c0_seq3,3580,38.9665,0.46455168,376,4232,,,,,,,,,1.00E-110,CHOYP_LOC100376827.1.1,,,,,,,,, comp140730_c0_seq4,3283,39.0192,0.40032381,78,864,,6.00E-146,Q5RBM1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2),GO:0016021; GO:0008250; GO:0006487; GO:0016757,"integral to membrane; oligosaccharyltransferase complex; protein N-linked glycosylation; transferase activity, transferring glycosyl groups",PF05817;,3.00E-112,CHOYP_LOC100376827.1.1,7.00E-73,ruditapes_c29330,,,,,RPN2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein N-linked glycosylation [GO:0006487] comp140731_c1_seq1,1531,47.6813,1.03240017,816,1182,,3.00E-174,Q0II68,2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase),2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase),GO:0001760; GO:0005829; GO:0046872; GO:0046874,aminocarboxymuconate-semialdehyde decarboxylase activity; cytosol; metal ion binding; quinolinate metabolic process,PF04909;,3.00E-158,CHOYP_LOC100377682.1.1,,,,,,,ACMSD_BOVIN,Bos taurus (Bovine),quinolinate metabolic process [GO:0046874]; regulation of quinolinate biosynthetic process [GO:1904984]; tryptophan metabolic process [GO:0006568] comp140732_c0_seq1,3300,39.8182,0.43572118,25,18,,3.00E-127,P07686,Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A],Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A],GO:0001669; GO:0043615; GO:0004563; GO:0005975; GO:0008219; GO:0006874; GO:0044267; GO:0030207; GO:0006689; GO:0006687; GO:0030214; GO:0042340; GO:0019915; GO:0007626; GO:0043202; GO:0007040; GO:0008049; GO:0016020; GO:0042552; GO:0050885; GO:0009313; GO:0048477; GO:0007341; GO:0008654; GO:0045944; GO:0046982; GO:0042803; GO:0008360; GO:0007605; GO:0001501,acrosomal vesicle; astrocyte cell migration; beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; cell death; cellular calcium ion homeostasis; cellular protein metabolic process; chondroitin sulfate catabolic process; ganglioside catabolic process; glycosphingolipid metabolic process; hyaluronan catabolic process; keratan sulfate catabolic process; lipid storage; locomotory behavior; lysosomal lumen; lysosome organization; male courtship behavior; membrane; myelination; neuromuscular process controlling balance; oligosaccharide catabolic process; oogenesis; penetration of zona pellucida; phospholipid biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; protein homodimerization activity; regulation of cell shape; sensory perception of sound; skeletal system development,PF00728;PF14845;,4.00E-161,CHOYP_CPIPJ_CPIJ016910.1.1,,,,,,,HEXB_HUMAN,Homo sapiens (Human),astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501] comp140732_c0_seq2,1623,39.1251,0.38094864,0,0,,2.00E-12,P13670,"N,N'-diacetylchitobiase (Chitobiase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)","N,N'-diacetylchitobiase (Chitobiase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)",GO:0004563; GO:0009279; GO:0006032; GO:0030247; GO:0000272,beta-N-acetylhexosaminidase activity; cell outer membrane; chitin catabolic process; polysaccharide binding; polysaccharide catabolic process,PF03173;PF00728;PF02838;,,,,,,,,,CHB_VIBHA,Vibrio harveyi (Beneckea harveyi),chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] comp140732_c0_seq3,2978,40.1276,0.42435902,7,2,,3.00E-128,P07686,Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A],Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A],GO:0001669; GO:0043615; GO:0004563; GO:0005975; GO:0008219; GO:0006874; GO:0044267; GO:0030207; GO:0006689; GO:0006687; GO:0030214; GO:0042340; GO:0019915; GO:0007626; GO:0043202; GO:0007040; GO:0008049; GO:0016020; GO:0042552; GO:0050885; GO:0009313; GO:0048477; GO:0007341; GO:0008654; GO:0045944; GO:0046982; GO:0042803; GO:0008360; GO:0007605; GO:0001501,acrosomal vesicle; astrocyte cell migration; beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; cell death; cellular calcium ion homeostasis; cellular protein metabolic process; chondroitin sulfate catabolic process; ganglioside catabolic process; glycosphingolipid metabolic process; hyaluronan catabolic process; keratan sulfate catabolic process; lipid storage; locomotory behavior; lysosomal lumen; lysosome organization; male courtship behavior; membrane; myelination; neuromuscular process controlling balance; oligosaccharide catabolic process; oogenesis; penetration of zona pellucida; phospholipid biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; protein homodimerization activity; regulation of cell shape; sensory perception of sound; skeletal system development,PF00728;PF14845;,3.00E-161,CHOYP_CPIPJ_CPIJ016910.1.1,,,,,,,HEXB_HUMAN,Homo sapiens (Human),astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501] comp140734_c0_seq1,766,29.5039,0.92446923,0,0,,,,,,,,,,,5.00E-16,ruditapes_c14826,,,,,,, comp140735_c0_seq1,1943,36.4385,1.01014488,0,23,,7.00E-30,Q9R141,Solute carrier family 22 member 4 (Organic cation/carnitine transporter 1),Solute carrier family 22 member 4 (Organic cation/carnitine transporter 1),GO:0005524; GO:0016021; GO:0015651; GO:0006814; GO:0015293,ATP binding; integral to membrane; quaternary ammonium group transmembrane transporter activity; sodium ion transport; symporter activity,PF00083;,,,,,,,,,S22A4_RAT,Rattus norvegicus (Rat),quaternary ammonium group transport [GO:0015697]; sodium ion transport [GO:0006814] comp140735_c0_seq2,1643,35.3013,1.10046778,0,89,,2.00E-08,Q504N2,Solute carrier family 22 member 15,Solute carrier family 22 member 15,GO:0016021; GO:0006811; GO:0022857,integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,S22AF_MOUSE,Mus musculus (Mouse),ion transport [GO:0006811] comp140735_c0_seq4,1440,35.2778,1.02936613,0,18,,2.00E-07,O76082,Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2),Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2),GO:0005524; GO:0042895; GO:0016324; GO:0016323; GO:0031526; GO:0015226; GO:0015238; GO:0016021; GO:0060731; GO:0052106; GO:0006814; GO:0070715; GO:0015293,ATP binding; antibiotic transporter activity; apical plasma membrane; basolateral plasma membrane; brush border membrane; carnitine transmembrane transporter activity; drug transmembrane transporter activity; integral to membrane; positive regulation of intestinal epithelial structure maintenance; quorum sensing involved in interaction with host; sodium ion transport; sodium-dependent organic cation transport; symporter activity,PF00083;,,,,,,,,,S22A5_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; drug transport [GO:0015893]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; quorum sensing involved in interaction with host [GO:0052106]; sodium-dependent organic cation transport [GO:0070715]; sodium ion transport [GO:0006814] comp140735_c0_seq5,438,39.4977,0.93879131,0,6,,3.00E-14,Q6A4L0,Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3),Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3),GO:0016021; GO:0022857,integral to membrane; transmembrane transporter activity,PF00083;,,,,,,,,,S22AD_MOUSE,Mus musculus (Mouse),nicotinate transport [GO:2001142]; urate transport [GO:0015747] comp140735_c2_seq2,339,47.1976,0.74949479,0,52,,1.00E-06,Q1RPP5,Solute carrier family 22 member 7 (Organic anion transporter 2),Solute carrier family 22 member 7 (Organic anion transporter 2),GO:0016323; GO:0016021; GO:0008514; GO:0015711; GO:0035634,basolateral plasma membrane; integral to membrane; organic anion transmembrane transporter activity; organic anion transport; response to stilbenoid,PF00083;,,,,,,,,,S22A7_PIG,Sus scrofa (Pig), comp140740_c0_seq3,792,49.3687,0.74705724,23,24,,4.00E-24,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp140741_c0_seq1,213,29.108,0.44584316,0,3,,,,,,,,,,,1.00E-11,ruditapes_c15855,,,,,,, comp140742_c0_seq1,1160,42.3276,0.48863673,70,303,,2.00E-39,Q5ZIN2,tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2),tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2),GO:0006397; GO:0003676; GO:0090305; GO:0006388; GO:0000213; GO:0000214,"mRNA processing; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; tRNA splicing, via endonucleolytic cleavage and ligation; tRNA-intron endonuclease activity; tRNA-intron endonuclease complex",PF01974;PF02778;,,,,,,,,,SEN2_CHICK,Gallus gallus (Chicken),mRNA processing [GO:0006397]; tRNA-type intron splice site recognition and cleavage [GO:0000379] comp140743_c1_seq2,1243,37.6508,0.467362,56,704,,5.00E-42,Q6P8C4,H/ACA ribonucleoprotein complex subunit 2-like protein (Nucleolar protein family A member 2-like protein) (snoRNP protein NHP2-like protein),H/ACA ribonucleoprotein complex subunit 2-like protein (Nucleolar protein family A member 2-like protein) (snoRNP protein NHP2-like protein),GO:0005730; GO:0031118; GO:0005732; GO:0030515,nucleolus; rRNA pseudouridine synthesis; small nucleolar ribonucleoprotein complex; snoRNA binding,PF01248;,,,1.00E-33,ruditapes2_c1073,,,,,NHP2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cleavage involved in rRNA processing [GO:0000469]; maturation of LSU-rRNA [GO:0000470]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120]; translation [GO:0006412] comp140746_c3_seq1,283,51.9435,0.210373,17,73,,3.00E-11,Q08BD8,Mitochondrial fission regulator 2,Mitochondrial fission regulator 2,GO:0005739,mitochondrion,PF05308;,,,,,,,,,FA54A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),aerobic respiration [GO:0009060]; mitochondrial fission [GO:0000266] comp140746_c3_seq2,766,41.5144,0.36779283,111,266,,5.00E-09,Q6P444,Mitochondrial fission regulator 2 (DUF729 domain-containing protein 1),Mitochondrial fission regulator 2 (DUF729 domain-containing protein 1),GO:0009060; GO:0000266; GO:0005739,aerobic respiration; mitochondrial fission; mitochondrion,PF05308;,4.00E-14,CHOYP_NEMVEDRAFT_V1G237042.2.2,,,,,,,FA54A_HUMAN,Homo sapiens (Human),aerobic respiration [GO:0009060]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005] comp140747_c2_seq1,1164,37.0275,0.38347625,61,658,,3.00E-42,Q5M823,NudC domain-containing protein 2,NudC domain-containing protein 2,GO:0000777; GO:0005737; GO:0005815; GO:0000922,condensed chromosome kinetochore; cytoplasm; microtubule organizing center; spindle pole,PF04969;,,,,,,,,,NUDC2_RAT,Rattus norvegicus (Rat), comp140748_c0_seq4,960,36.9792,0.2763615,27,182,,6.00E-20,Q9D1L9,Ragulator complex protein LAMTOR5 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5),Ragulator complex protein LAMTOR5 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5),GO:0071986; GO:0071230; GO:0005829; GO:0005085; GO:0005764; GO:0043066; GO:0043154; GO:0032008; GO:0061462; GO:0008361; GO:0019079,Ragulator complex; cellular response to amino acid stimulus; cytosol; guanyl-nucleotide exchange factor activity; lysosome; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of TOR signaling cascade; protein localization to lysosome; regulation of cell size; viral genome replication,PF16672;,,,1.00E-62,ruditapes2_c606,,,,,HBXIP_MOUSE,Mus musculus (Mouse),cellular response to amino acid stimulus [GO:0071230]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; protein localization to lysosome [GO:0061462]; regulation of cell size [GO:0008361]; viral genome replication [GO:0019079] comp140751_c0_seq1,2242,43.8894,0.60672089,108,513,,7.00E-172,O14730,Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog),Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog),GO:0005524; GO:0007059; GO:0004674,ATP binding; chromosome segregation; protein serine/threonine kinase activity,,4.00E-95,CHOYP_RIOK3.1.1,,,,,,,RIOK3_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; rRNA processing [GO:0006364] comp140753_c0_seq1,740,43.7838,0.56895067,76,35,,3.00E-12,Q8N4L8,Coiled-coil domain-containing protein 24,Coiled-coil domain-containing protein 24,,,PF15669;,2.00E-36,CHOYP_LOC100366431.1.1,,,,,,,CCD24_HUMAN,Homo sapiens (Human), comp140754_c2_seq1,3419,40.1287,0.5355123,122,287,,9.00E-14,Q8TF01,"Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)","Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)",GO:0016607,nuclear speck,PF15996;,,,,,,,,,PNISR_HUMAN,Homo sapiens (Human), comp140754_c2_seq2,475,43.5789,0.50000222,3,18,,,,,,,,,3.00E-19,CHOYP_BRAFLDRAFT_81797.1.1,,,,,,,,, comp140755_c0_seq2,2676,46.3004,0.49069368,18,13,,0,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,4.00E-14,CHOYP_FYNA.1.1,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp140755_c0_seq3,4070,45.8477,0.52596356,150,164,,0,P00522,Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson),GO:0005524; GO:0045179; GO:0030424; GO:0016199; GO:0005911; GO:0007417; GO:0007303; GO:0005829; GO:0007391; GO:0003382; GO:0019897; GO:0008045; GO:0005927; GO:0045886; GO:0001764; GO:0004715; GO:0003402; GO:0008064; GO:0008360; GO:0032880; GO:0031647; GO:0007370,"ATP binding; apical cortex; axon; axon midline choice point recognition; cell-cell junction; central nervous system development; cytoplasmic transport, nurse cell to oocyte; cytosol; dorsal closure; epithelial cell morphogenesis; extrinsic to plasma membrane; motor neuron axon guidance; muscle tendon junction; negative regulation of synaptic growth at neuromuscular junction; neuron migration; non-membrane spanning protein tyrosine kinase activity; planar cell polarity pathway involved in axis elongation; regulation of actin polymerization or depolymerization; regulation of cell shape; regulation of protein localization; regulation of protein stability; ventral furrow formation",PF08919;PF07714;PF00017;PF00018;,0,CHOYP_ABL1.1.1,,,,,,,ABL_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]" comp140761_c0_seq4,753,32.4037,0.20374284,14,27,,,,,,,,,,,4.00E-68,ruditapes_c22334,,,,,,, comp140762_c1_seq2,1426,43.338,0.34418012,45,203,,5.00E-111,Q8WVB3,Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase),Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase),GO:0004563; GO:0005975; GO:0005737; GO:0005634,beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; cytoplasm; nucleus,PF00728;,1.00E-36,CHOYP_HEXDC.1.1,,,,,,,HEXDC_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975] comp140765_c0_seq2,2139,47.6858,0.49525775,114,108,,2.00E-105,Q8CG73,Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein),Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein),GO:0043010; GO:0005911; GO:0005813; GO:0021549; GO:0042384; GO:0035085; GO:0022038; GO:0007368; GO:0035115; GO:0035116; GO:0007163; GO:0060322; GO:0001701; GO:0001822; GO:0021670; GO:0001889; GO:0005932; GO:0045744; GO:0021532; GO:0043584; GO:0021772; GO:0060039; GO:0008589; GO:0005923,camera-type eye development; cell-cell junction; centrosome; cerebellum development; cilium assembly; cilium axoneme; corpus callosum development; determination of left/right symmetry; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; establishment or maintenance of cell polarity; head development; in utero embryonic development; kidney development; lateral ventricle development; liver development; microtubule basal body; negative regulation of G-protein coupled receptor protein signaling pathway; neural tube patterning; nose development; olfactory bulb development; pericardium development; regulation of smoothened signaling pathway; tight junction,PF00168;PF11618;,,,,,,,,,FTM_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; camera-type eye development [GO:0043010]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; head development [GO:0060322]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; limb morphogenesis [GO:0035108]; liver development [GO:0001889]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]; telencephalon development [GO:0021537] comp140765_c1_seq1,793,44.7667,0.39987977,70,27,,,,,,,,,2.00E-107,CHOYP_LOC585739.1.1,,,,,,,,, comp140766_c1_seq1,1886,39.0244,0.57681485,3828,81,,3.00E-118,Q41629,"ADP,ATP carrier protein 1, mitochondrial (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1)","ADP,ATP carrier protein 1, mitochondrial (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1)",GO:0016021; GO:0005743; GO:0055085; GO:0005215,integral to membrane; mitochondrial inner membrane; transmembrane transport; transporter activity,PF00153;,5.00E-87,CHOYP_LOC100633390.3.5,1.00E-23,ruditapes_lrc39310,,,,,ADT1_WHEAT,Triticum aestivum (Wheat),transmembrane transport [GO:0055085] comp140766_c1_seq2,1869,38.9513,0.58437517,3744,35,male>female,3.00E-127,P02723,"ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT)","ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT)",GO:0016021; GO:0005743; GO:0055085; GO:0005215,integral to membrane; mitochondrial inner membrane; transmembrane transport; transporter activity,PF00153;,1.00E-100,CHOYP_LOC100633390.3.5,5.00E-91,ruditapes_c408,,,,,ADT_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),translation [GO:0006412]; transmembrane transport [GO:0055085] comp140766_c1_seq4,702,47.2934,0.56587872,1140,18,,5.00E-100,P02723,"ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT)","ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT)",GO:0016021; GO:0005743; GO:0055085; GO:0005215,integral to membrane; mitochondrial inner membrane; transmembrane transport; transporter activity,PF00153;,,,,,,,,,ADT_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),translation [GO:0006412]; transmembrane transport [GO:0055085] comp140767_c0_seq1,1774,43.2356,0.55120437,484,2918,,4.00E-104,P07871,"3-ketoacyl-CoA thiolase B, peroxisomal (EC 2.3.1.16) (Acetyl-CoA acyltransferase B) (Beta-ketothiolase B) (Peroxisomal 3-oxoacyl-CoA thiolase B)","3-ketoacyl-CoA thiolase B, peroxisomal (EC 2.3.1.16) (Acetyl-CoA acyltransferase B) (Beta-ketothiolase B) (Peroxisomal 3-oxoacyl-CoA thiolase B)",GO:0003988; GO:0006631; GO:0005777,acetyl-CoA C-acyltransferase activity; fatty acid metabolic process; peroxisome,PF02803;PF00108;,6.00E-92,CHOYP_THIKA.1.1,3.00E-30,ruditapes_c24329,,,,,THIKB_RAT,Rattus norvegicus (Rat),fatty acid metabolic process [GO:0006631] comp140768_c0_seq1,2381,39.4372,0.45472487,48,154,,1.00E-83,Q96DF8,Protein DGCR14 (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2),Protein DGCR14 (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2),GO:0071013; GO:0000398; GO:0007399,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nervous system development",PF09751;,,,,,,,,,DGC14_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; nervous system development [GO:0007399]" comp140768_c0_seq2,2282,39.8335,0.45405296,0,29,,7.00E-63,O44424,Protein DGCR14 homolog (Protein Es2) (dEs2),Protein DGCR14 homolog (Protein Es2) (dEs2),GO:0071013; GO:0000398; GO:0007399,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nervous system development",PF09751;,4.00E-45,CHOYP_BRAFLDRAFT_164902.1.1,,,,,,,DGC14_DROME,Drosophila melanogaster (Fruit fly),"mRNA splicing, via spliceosome [GO:0000398]; nervous system development [GO:0007399]" comp140770_c0_seq1,2713,41.0984,0.76053273,66,88,,4.00E-53,Q9UBI9,Headcase protein homolog (hHDC),Headcase protein homolog (hHDC),GO:0030323,respiratory tube development,PF16002;PF15353;,2.00E-80,CHOYP_LOC100644701.2.2,,,,,,,HDC_HUMAN,Homo sapiens (Human),negative regulation of mitotic cell cycle [GO:0045930]; respiratory tube development [GO:0030323] comp140770_c0_seq2,2365,41.9873,0.82697028,41,11,,2.00E-56,Q9N2M8,Headcase protein [Cleaved into: Headcase short protein],Headcase protein [Cleaved into: Headcase short protein],GO:0016246; GO:0048675; GO:0035147; GO:0005737; GO:0007476; GO:0035155; GO:0007430,"RNA interference; axon extension; branch fusion, open tracheal system; cytoplasm; imaginal disc-derived wing morphogenesis; negative regulation of terminal cell fate specification, open tracheal system; terminal branching, open tracheal system",PF16002;PF15353;,2.00E-81,CHOYP_LOC100644701.1.2,,,,,,,HDC_DROME,Drosophila melanogaster (Fruit fly),"axon extension [GO:0048675]; branch fusion, open tracheal system [GO:0035147]; cell differentiation [GO:0030154]; imaginal disc-derived wing morphogenesis [GO:0007476]; instar larval or pupal development [GO:0002165]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; neurogenesis [GO:0022008]; open tracheal system development [GO:0007424]; regulation of neuron remodeling [GO:1904799]; RNA interference [GO:0016246]; salivary gland cell autophagic cell death [GO:0035071]; terminal branching, open tracheal system [GO:0007430]" comp140774_c0_seq1,7149,35.6693,0.4714279,0,0,,2.00E-89,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,2.00E-61,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140774_c0_seq11,2698,46.7754,0.43207379,0,0,,2.00E-12,Q5RB68,Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),GO:0005737; GO:0005856; GO:0003730; GO:0048027; GO:0051028; GO:0000166; GO:0005634; GO:0006417,cytoplasm; cytoskeleton; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00013;PF00076;,,,,,,,,,IF2B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp140774_c0_seq12,2689,46.5972,0.43714796,0,0,,6.00E-94,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,6.00E-62,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140774_c0_seq13,2665,46.7542,0.43115759,0,0,,2.00E-12,Q5RB68,Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),GO:0005737; GO:0005856; GO:0003730; GO:0048027; GO:0051028; GO:0000166; GO:0005634; GO:0006417,cytoplasm; cytoskeleton; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00013;PF00076;,6.00E-62,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,IF2B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp140774_c0_seq14,2686,46.7982,0.43369805,0,0,,7.00E-94,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,9.00E-22,CHOYP_BRAFLDRAFT_124476.4.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140774_c0_seq16,2701,46.5753,0.43549433,0,0,,2.00E-12,Q5RB68,Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),GO:0005737; GO:0005856; GO:0003730; GO:0048027; GO:0051028; GO:0000166; GO:0005634; GO:0006417,cytoplasm; cytoskeleton; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00013;PF00076;,,,,,,,,,IF2B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp140774_c0_seq17,2653,46.7772,0.43280471,0,0,,4.00E-94,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,6.00E-62,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140774_c0_seq18,7171,35.6993,0.47357639,0,0,,3.00E-08,P57723,Poly(rC)-binding protein 4 (Alpha-CP4),Poly(rC)-binding protein 4 (Alpha-CP4),GO:0003677; GO:0003723; GO:0005737; GO:0030529,DNA binding; RNA binding; cytoplasm; ribonucleoprotein complex,PF00013;,,,,,,,,,PCBP4_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; regulation of mRNA stability [GO:0043488]" comp140774_c0_seq2,7138,35.6542,0.48169465,135,81,,1.00E-90,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,2.00E-61,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140774_c0_seq3,2734,46.5984,0.436351,0,0,,2.00E-12,Q5RB68,Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2),GO:0005737; GO:0005856; GO:0003730; GO:0048027; GO:0051028; GO:0000166; GO:0005634; GO:0006417,cytoplasm; cytoskeleton; mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00013;PF00076;,,,,,,,,,IF2B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp140774_c0_seq4,7174,35.6287,0.47535416,0,0,,,,,,,,,2.00E-61,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,,, comp140774_c0_seq6,7207,35.6875,0.47588029,0,0,,2.00E-90,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,2.00E-61,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140774_c0_seq8,2722,46.6201,0.43798165,0,0,,1.00E-93,Q96I24,Far upstream element-binding protein 3 (FUSE-binding protein 3),Far upstream element-binding protein 3 (FUSE-binding protein 3),GO:0003677; GO:0003723; GO:0005737; GO:0005634; GO:0045893; GO:0006351,"DNA binding; RNA binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;,6.00E-62,CHOYP_BRAFLDRAFT_124476.1.4,,,,,,,FUBP3_HUMAN,Homo sapiens (Human),"positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp140778_c0_seq2,1407,35.3945,0.4362334,0,29,,1.00E-55,Q05B60,Uridine diphosphate glucose pyrophosphatase (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14),Uridine diphosphate glucose pyrophosphatase (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14),GO:0047631; GO:0008768; GO:0005737; GO:0046872,ADP-ribose diphosphatase activity; UDP-sugar diphosphatase activity; cytoplasm; metal ion binding,,,,,,,,,,NUD14_BOVIN,Bos taurus (Bovine), comp140779_c1_seq1,3482,44.687,0.52236298,5,4,,3.00E-113,Q5SUV2,MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),GO:0030154; GO:0005737; GO:0016020; GO:0007275; GO:0007283; GO:0007268,cell differentiation; cytoplasm; membrane; multicellular organismal development; spermatogenesis; synaptic transmission,PF14646;,2.00E-107,CHOYP_LOC579832.1.2,,,,,,,MYBPP_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140779_c1_seq2,3437,44.6901,0.5236298,15,12,,4.00E-106,Q8TBZ2,MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),GO:0030154; GO:0005737; GO:0016020; GO:0007275; GO:0007283; GO:0007268,cell differentiation; cytoplasm; membrane; multicellular organismal development; spermatogenesis; synaptic transmission,PF14646;,1.00E-47,CHOYP_LOC752157.1.1,,,,,,,MYBPP_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140779_c1_seq4,3434,44.7001,0.54201188,0,0,,3.00E-113,Q5SUV2,MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),GO:0030154; GO:0005737; GO:0016020; GO:0007275; GO:0007283; GO:0007268,cell differentiation; cytoplasm; membrane; multicellular organismal development; spermatogenesis; synaptic transmission,PF14646;,2.00E-107,CHOYP_LOC579832.1.2,,,,,,,MYBPP_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140780_c0_seq1,3250,37.3846,0.62422854,5986,250,,9.00E-56,Q0VFZ6,Coiled-coil domain-containing protein 173,Coiled-coil domain-containing protein 173,,,,1.00E-128,CHOYP_LOC100372239.1.1,,,,,,,CC173_HUMAN,Homo sapiens (Human), comp140781_c1_seq1,817,40.5141,0.7481536,63,398,,4.00E-82,Q86X83,COMM domain-containing protein 2,COMM domain-containing protein 2,,,PF07258;,4.00E-71,CHOYP_CEP63.2.2,,,,,,,COMD2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140782_c1_seq2,3149,36.0432,0.50205327,254,945,,3.00E-21,Q49AM3,Tetratricopeptide repeat protein 31 (TPR repeat protein 31),Tetratricopeptide repeat protein 31 (TPR repeat protein 31),,,,1.00E-141,CHOYP_LOC100368918.1.2,1.00E-113,ruditapes2_c3776,,,,,TTC31_HUMAN,Homo sapiens (Human), comp140782_c2_seq1,455,41.3187,0.82655888,7,39,,,,,,,,,2.00E-22,CHOYP_PLE7327_0069.1.1,,,,,,,,, comp140785_c2_seq1,1605,39.9377,0.40786122,92,694,,3.00E-159,Q8TCT9,Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase),Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase),GO:0042500; GO:0009986; GO:0071458; GO:0071556; GO:0033619; GO:0005886; GO:0042803; GO:0005791,"aspartic endopeptidase activity, intramembrane cleaving; cell surface; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; membrane protein proteolysis; plasma membrane; protein homodimerization activity; rough endoplasmic reticulum",PF04258;,2.00E-155,CHOYP_BRAFLDRAFT_87838.1.1,,,,,,,HM13_HUMAN,Homo sapiens (Human),"membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; protein homotetramerization [GO:0051289]; signal peptide processing [GO:0006465]" comp140786_c0_seq1,2371,39.8566,0.47862045,409,851,,1.00E-25,Q9UKM9,RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog),RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog),GO:0003723; GO:0071013; GO:0000398; GO:0000166,"RNA binding; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleotide binding",PF00076;,7.00E-23,CHOYP_BRAFLDRAFT_126700.1.2,,,,,,,RALY_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]" comp140787_c0_seq1,1953,39.5289,0.60378229,27,338,,8.00E-179,Q9BRS2,Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1),Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,,1.00E-126,CHOYP_BRAFLDRAFT_124526.1.1,,,,,,,RIOK1_HUMAN,Homo sapiens (Human),rRNA processing [GO:0006364] comp140787_c0_seq2,1965,39.6438,0.59708458,24,254,,1.00E-117,O42650,Serine/threonine-protein kinase rio1 (EC 2.7.11.1),Serine/threonine-protein kinase rio1 (EC 2.7.11.1),GO:0005524; GO:0005829; GO:0000070; GO:0005634; GO:0004674; GO:0007346,ATP binding; cytosol; mitotic sister chromatid segregation; nucleus; protein serine/threonine kinase activity; regulation of mitotic cell cycle,,,,,,,,,,RIO1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp140788_c0_seq2,2038,36.6045,0.35417761,5,3,,1.00E-117,Q58DK5,Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase),Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase),GO:0071353; GO:0006783; GO:0032791; GO:0004655; GO:0051260; GO:0006782; GO:0008270,cellular response to interleukin-4; heme biosynthetic process; lead ion binding; porphobilinogen synthase activity; protein homooligomerization; protoporphyrinogen IX biosynthetic process; zinc ion binding,PF00490;,3.00E-109,CHOYP_HEM2.1.1,,,,,,,HEM2_BOVIN,Bos taurus (Bovine),cellular response to interleukin-4 [GO:0071353]; heme biosynthetic process [GO:0006783]; protein homooligomerization [GO:0051260]; protoporphyrinogen IX biosynthetic process [GO:0006782] comp140788_c1_seq1,313,43.131,0.49216803,32,46,,1.00E-35,Q5R971,Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase),Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase),GO:0006783; GO:0032791; GO:0004655; GO:0006782; GO:0008270,heme biosynthetic process; lead ion binding; porphobilinogen synthase activity; protoporphyrinogen IX biosynthetic process; zinc ion binding,PF00490;,4.00E-22,CHOYP_HEM2.1.1,,,,,,,HEM2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] comp140793_c0_seq3,1275,45.8039,0.93179332,0,339,,3.00E-80,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp140795_c0_seq16,444,41.2162,0.58510935,0,0,,3.00E-29,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,2.00E-59,CHOYP_TRRAP.2.2,,,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140795_c0_seq2,881,43.1328,0.59168234,0,0,,,,,,,,,2.00E-69,CHOYP_LOC100123553.1.1,,,,,,,,, comp140795_c0_seq3,912,42.3246,0.5000006,7,4,,1.00E-13,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140795_c0_seq5,546,42.674,0.56658965,0,0,,,,,,,,,1.00E-69,CHOYP_LOC100123553.1.1,,,,,,,,, comp140798_c0_seq2,1409,42.8673,0.87558261,67,530,,5.00E-96,P33274,Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (Cytochrome P450-A3),Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (Cytochrome P450-A3),GO:0050544; GO:0019369; GO:0008391; GO:0070330; GO:0005789; GO:0020037; GO:0043231; GO:0005506; GO:0009636,arachidonic acid binding; arachidonic acid metabolic process; arachidonic acid monooxygenase activity; aromatase activity; endoplasmic reticulum membrane; heme binding; intracellular membrane-bounded organelle; iron ion binding; response to toxic substance,PF00067;,3.00E-25,CHOYP_BRAFLDRAFT_61250.5.14,,,,,,,CP4F1_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369]; icosanoid metabolic process [GO:0006690]; response to toxic substance [GO:0009636] comp140799_c0_seq1,4962,37.0415,0.57529733,33982,62166,,9.00E-103,Q2KI24,Methenyltetrahydrofolate synthase domain-containing protein,Methenyltetrahydrofolate synthase domain-containing protein,GO:0030272; GO:0005524; GO:0003723; GO:0009396,5-formyltetrahydrofolate cyclo-ligase activity; ATP binding; RNA binding; folic acid-containing compound biosynthetic process,PF01812;PF00076;,2.00E-45,CHOYP_BRAFLDRAFT_266781.1.2,1.00E-33,ruditapes_c6962,,,,,MTHSD_BOVIN,Bos taurus (Bovine), comp140800_c2_seq1,1756,37.9271,0.33811695,5,16,,8.00E-164,A3QK15,Acetoacetyl-CoA synthetase (EC 6.2.1.16),Acetoacetyl-CoA synthetase (EC 6.2.1.16),GO:0005524; GO:0030729; GO:0005829; GO:0006631,ATP binding; acetoacetate-CoA ligase activity; cytosol; fatty acid metabolic process,PF16177;PF00501;,,,,,,,,,AACS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid metabolic process [GO:0006631] comp140800_c2_seq2,1724,38.3411,0.33804603,6,15,,1.00E-26,Q3IFM6,Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme),Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme),GO:0016208; GO:0005524; GO:0003987; GO:0019427; GO:0046872,AMP binding; ATP binding; acetate-CoA ligase activity; acetyl-CoA biosynthetic process from acetate; metal ion binding,PF16177;PF00501;PF13193;,3.00E-152,CHOYP_AACS.1.1,,,,,,,ACSA_PSEHT,Pseudoalteromonas haloplanktis (strain TAC 125),acetyl-CoA biosynthetic process from acetate [GO:0019427] comp140800_c2_seq4,1003,40.678,0.39189129,31,127,,2.00E-28,Q9RRL7,Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme),Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme),GO:0016208; GO:0005524; GO:0003987; GO:0019427; GO:0046872,AMP binding; ATP binding; acetate-CoA ligase activity; acetyl-CoA biosynthetic process from acetate; metal ion binding,PF16177;PF00501;PF13193;,,,,,,,,,ACSA_DEIRA,Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422),acetyl-CoA biosynthetic process from acetate [GO:0019427] comp140801_c1_seq1,1396,38.3954,1.02102712,47,978,,,,,,,,,,,6.00E-12,ruditapes2_c1294,,,,,,, comp140802_c1_seq1,3139,38.3243,0.67868947,114,493,,1.00E-60,Q10651,Beta-amyloid-like protein,Beta-amyloid-like protein,GO:0010171; GO:0030154; GO:0031410; GO:0042395; GO:0008201; GO:0016021; GO:0002119; GO:0007399; GO:0043005; GO:0043025; GO:0046914,"body morphogenesis; cell differentiation; cytoplasmic vesicle; ecdysis, collagen and cuticulin-based cuticle; heparin binding; integral to membrane; nematode larval development; nervous system development; neuron projection; neuronal cell body; transition metal ion binding",PF10515;PF12924;PF12925;PF02177;,,,,,,,,,A4_CAEEL,Caenorhabditis elegans,"body morphogenesis [GO:0010171]; cell differentiation [GO:0030154]; ecdysis, collagen and cuticulin-based cuticle [GO:0042395]; nematode larval development [GO:0002119]; nervous system development [GO:0007399]" comp140802_c1_seq2,2871,39.3939,0.66678806,40,92,,2.00E-35,O73683,Amyloid beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) [Cleaved into: Beta-amyloid protein (A-beta) (Beta-APP)],Amyloid beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Beta-amyloid precursor protein) [Cleaved into: Beta-amyloid protein (A-beta) (Beta-APP)],GO:0008201; GO:0016021; GO:0004867; GO:0046914,heparin binding; integral to membrane; serine-type endopeptidase inhibitor activity; transition metal ion binding,PF10515;PF12924;PF12925;PF02177;PF03494;PF00014;,3.00E-34,CHOYP_A4.2.3,2.00E-34,ruditapes2_c2610,,,,,A4_TETFL,Tetraodon fluviatilis (Green pufferfish) (Chelonodon fluviatilis), comp140804_c0_seq1,2306,37.0338,0.24222485,526,1087,,6.00E-17,P77851,3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD),3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD),GO:0003857; GO:0008691; GO:0070403; GO:0019605,3-hydroxyacyl-CoA dehydrogenase activity; 3-hydroxybutyryl-CoA dehydrogenase activity; NAD+ binding; butyrate metabolic process,PF00725;PF02737;,4.00E-38,CHOYP_LOC100892111.1.1,,,,,,,HBD_THETC,Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum),butyrate metabolic process [GO:0019605] comp140809_c0_seq1,2433,39.0053,0.54227479,0,0,,0,P63155,Crooked neck-like protein 1 (Crooked neck homolog) (Crooked neck protein),Crooked neck-like protein 1 (Crooked neck homolog) (Crooked neck protein),GO:0003723; GO:0071013; GO:0005681; GO:0000245,RNA binding; catalytic step 2 spliceosome; spliceosomal complex; spliceosomal complex assembly,PF02184;,,,,,,,,,CRNL1_RAT,Rattus norvegicus (Rat),cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to leukemia inhibitory factor [GO:1990830]; cerebral cortex development [GO:0021987]; spliceosomal complex assembly [GO:0000245] comp140809_c0_seq2,2495,40.7615,0.56736032,0,0,,0,P17886,Protein crooked neck,Protein crooked neck,GO:0007443; GO:0008366; GO:0071013; GO:0005813; GO:0051298; GO:0008347; GO:0000398; GO:0072686; GO:0016607; GO:0007438; GO:0071011; GO:0000381,"Malpighian tubule morphogenesis; axon ensheathment; catalytic step 2 spliceosome; centrosome; centrosome duplication; glial cell migration; mRNA splicing, via spliceosome; mitotic spindle; nuclear speck; oenocyte development; precatalytic spliceosome; regulation of alternative mRNA splicing, via spliceosome",PF02184;,0,CHOYP_CRNL1.1.1,,,,,,,CRN_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; central nervous system development [GO:0007417]; centrosome duplication [GO:0051298]; glial cell migration [GO:0008347]; Malpighian tubule morphogenesis [GO:0007443]; mRNA splicing, via spliceosome [GO:0000398]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron fate commitment [GO:0048663]; oenocyte development [GO:0007438]; peripheral nervous system development [GO:0007422]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245]" comp140809_c0_seq5,2031,39.7341,0.58934248,0,0,,3.00E-08,Q99PK0,Pre-mRNA-splicing factor SYF1 (Adapter protein ATH-55) (XPA-binding protein 2),Pre-mRNA-splicing factor SYF1 (Adapter protein ATH-55) (XPA-binding protein 2),GO:0008380; GO:0001824; GO:0071013; GO:0006397; GO:0006351; GO:0006283,"RNA splicing; blastocyst development; catalytic step 2 spliceosome; mRNA processing; transcription, DNA-dependent; transcription-coupled nucleotide-excision repair",PF13181;,,,,,,,,,SYF1_RAT,Rattus norvegicus (Rat),"blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp140809_c0_seq7,2483,40.7974,0.56881163,0,0,,0,Q9BZJ0,Crooked neck-like protein 1 (Crooked neck homolog) (hCrn),Crooked neck-like protein 1 (Crooked neck homolog) (hCrn),GO:0003723; GO:0071013; GO:0005737; GO:0016607; GO:0000245,RNA binding; catalytic step 2 spliceosome; cytoplasm; nuclear speck; spliceosomal complex assembly,PF02184;,,,,,,,,,CRNL1_HUMAN,Homo sapiens (Human),"mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of defense response to virus by host [GO:0002230]; spliceosomal complex assembly [GO:0000245]; xenophagy [GO:0098792]" comp140809_c0_seq8,2019,39.8217,0.59012577,0,0,,3.00E-08,Q99PK0,Pre-mRNA-splicing factor SYF1 (Adapter protein ATH-55) (XPA-binding protein 2),Pre-mRNA-splicing factor SYF1 (Adapter protein ATH-55) (XPA-binding protein 2),GO:0008380; GO:0001824; GO:0071013; GO:0006397; GO:0006351; GO:0006283,"RNA splicing; blastocyst development; catalytic step 2 spliceosome; mRNA processing; transcription, DNA-dependent; transcription-coupled nucleotide-excision repair",PF13181;,,,,,,,,,SYF1_RAT,Rattus norvegicus (Rat),"blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp140809_c0_seq9,2897,40.0759,0.54004367,18,28,,0,Q9BZJ0,Crooked neck-like protein 1 (Crooked neck homolog) (hCrn),Crooked neck-like protein 1 (Crooked neck homolog) (hCrn),GO:0003723; GO:0071013; GO:0005737; GO:0016607; GO:0000245,RNA binding; catalytic step 2 spliceosome; cytoplasm; nuclear speck; spliceosomal complex assembly,PF02184;,0,CHOYP_CRNL1.1.1,,,,,,,CRNL1_HUMAN,Homo sapiens (Human),"mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of defense response to virus by host [GO:0002230]; spliceosomal complex assembly [GO:0000245]; xenophagy [GO:0098792]" comp140810_c1_seq1,1127,37.2671,0.46381615,458,2311,,2.00E-43,P52758,Ribonuclease UK114 (EC 3.1.-.-) (14.5 kDa translational inhibitor protein) (p14.5) (Heat-responsive protein 12) (UK114 antigen homolog),Ribonuclease UK114 (EC 3.1.-.-) (14.5 kDa translational inhibitor protein) (p14.5) (Heat-responsive protein 12) (UK114 antigen homolog),GO:0005737; GO:0019239; GO:0004519; GO:0005739; GO:0090305; GO:0005634; GO:0006449,cytoplasm; deaminase activity; endonuclease activity; mitochondrion; nucleic acid phosphodiester bond hydrolysis; nucleus; regulation of translational termination,PF01042;,6.00E-26,CHOYP_BRAFLDRAFT_118789.2.3,6.00E-81,ruditapes2_c2275,,,,,UK114_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; regulation of translational termination [GO:0006449]; response to lipid [GO:0033993]; response to salt [GO:1902074] comp140811_c0_seq2,1415,37.2438,0.9039264,0,840,female,8.00E-07,Q51330,Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein),Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein),GO:0015297; GO:0016021; GO:0006811; GO:0005886,antiporter activity; integral to membrane; ion transport; plasma membrane,PF07690;,,,,,,,,,OXLT_OXAFO,Oxalobacter formigenes,ion transport [GO:0006811] comp140812_c1_seq1,1128,38.6525,0.66519422,120,463,,8.00E-39,O60344,Endothelin-converting enzyme 2 (ECE-2) [Includes: Methyltransferase-like region (EC 2.1.1.-); Endothelin-converting enzyme 2 region (EC 3.4.24.71)],Endothelin-converting enzyme 2 (ECE-2) [Includes: Methyltransferase-like region (EC 2.1.1.-); Endothelin-converting enzyme 2 region (EC 3.4.24.71)],GO:0000139; GO:0007420; GO:0010002; GO:0007267; GO:0030659; GO:0016021; GO:0046872; GO:0004222; GO:0008168; GO:0016486; GO:0006508,Golgi membrane; brain development; cardioblast differentiation; cell-cell signaling; cytoplasmic vesicle membrane; integral to membrane; metal ion binding; metalloendopeptidase activity; methyltransferase activity; peptide hormone processing; proteolysis,PF01431;PF05649;,,,,,,,,,ECE2_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; cardioblast differentiation [GO:0010002]; cell-cell signaling [GO:0007267]; heart development [GO:0007507]; peptide hormone processing [GO:0016486] comp140813_c0_seq1,598,43.6455,0.43749362,13,7,,1.00E-21,Q7TSH2,Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,3.00E-89,CHOYP_LOC100643035.1.1,,,,,,,KPBB_MOUSE,Mus musculus (Mouse),glycogen metabolic process [GO:0005977] comp140813_c0_seq2,1901,43.293,0.59742692,14,54,,1.00E-128,Q9W391,Probable phosphorylase b kinase regulatory subunit alpha (Phosphorylase kinase subunit alpha),Probable phosphorylase b kinase regulatory subunit alpha (Phosphorylase kinase subunit alpha),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,2.00E-86,CHOYP_LOC100643035.1.1,,,,,,,KPBA_DROME,Drosophila melanogaster (Fruit fly),glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp140813_c0_seq4,1302,42.3963,0.62768329,22,8,,8.00E-22,Q93100,Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005829; GO:0006006; GO:0005980; GO:0004553; GO:0005886; GO:0044281,"cytosol; glucose metabolic process; glycogen catabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane; small molecule metabolic process",PF00723;,,,,,,,,,KPBB_HUMAN,Homo sapiens (Human),generation of precursor metabolites and energy [GO:0006091]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977] comp140814_c0_seq1,2501,40.3039,0.44514828,150,286,,0,P83888,Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1),Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1),GO:0005525; GO:0003924; GO:0045177; GO:0031252; GO:0005814; GO:0005813; GO:0005929; GO:0000794; GO:0005881; GO:0031122; GO:0000930; GO:0000212; GO:0007020; GO:0000242; GO:0005827; GO:0051258,GTP binding; GTPase activity; apical part of cell; cell leading edge; centriole; centrosome; cilium; condensed nuclear chromosome; cytoplasmic microtubule; cytoplasmic microtubule organization; gamma-tubulin complex; meiotic spindle organization; microtubule nucleation; pericentriolar material; polar microtubule; protein polymerization,PF00091;PF03953;,0,CHOYP_TBG1.1.1,,,,,,,TBG1_RAT,Rattus norvegicus (Rat),cytoplasmic microtubule organization [GO:0031122]; meiotic spindle organization [GO:0000212]; microtubule nucleation [GO:0007020] comp140814_c0_seq2,1289,43.4445,0.46100269,2,0,,0,Q32KM1,Tubulin gamma-2 chain (Gamma-2-tubulin),Tubulin gamma-2 chain (Gamma-2-tubulin),GO:0005525; GO:0003924; GO:0005881; GO:0031122; GO:0000930; GO:0007020; GO:0000242; GO:0051258; GO:0005876,GTP binding; GTPase activity; cytoplasmic microtubule; cytoplasmic microtubule organization; gamma-tubulin complex; microtubule nucleation; pericentriolar material; protein polymerization; spindle microtubule,PF00091;PF03953;,,,,,,,,,TBG2_BOVIN,Bos taurus (Bovine),cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] comp140817_c1_seq1,4338,44.9285,0.70001108,0,0,,3.00E-83,Q6RHR9,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)",GO:0005524; GO:0005737; GO:0005634; GO:0005886; GO:0005923,ATP binding; cytoplasm; nucleus; plasma membrane; tight junction,PF00625;PF00595;PF00397;,2.00E-51,CHOYP_MAGI1.1.1,,,,,,,MAGI1_MOUSE,Mus musculus (Mouse),neuron death [GO:0070997] comp140817_c1_seq10,5471,44.6902,0.69967363,0,0,,9.00E-149,Q9WVQ1,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)",GO:0030165; GO:0060395; GO:0031697; GO:0016482; GO:0030425; GO:0072015; GO:0005770; GO:0071850; GO:0032926; GO:0030336; GO:0008285; GO:0051898; GO:0038180; GO:0005634; GO:0048471; GO:0019902; GO:0005886; GO:0010976; GO:0032516; GO:0002092; GO:0014069; GO:0043234; GO:0051291; GO:0043113; GO:0030159; GO:0004871; GO:0036057; GO:0005923,PDZ domain binding; SMAD protein signal transduction; beta-1 adrenergic receptor binding; cytoplasmic transport; dendrite; glomerular visceral epithelial cell development; late endosome; mitotic cell cycle arrest; negative regulation of activin receptor signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase B signaling cascade; nerve growth factor signaling pathway; nucleus; perinuclear region of cytoplasm; phosphatase binding; plasma membrane; positive regulation of neuron projection development; positive regulation of phosphoprotein phosphatase activity; positive regulation of receptor internalization; postsynaptic density; protein complex; protein heterooligomerization; receptor clustering; receptor signaling complex scaffold activity; signal transducer activity; slit diaphragm; tight junction,PF00625;PF00595;PF00397;,,,,,,,,,MAGI2_MOUSE,Mus musculus (Mouse),cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] comp140817_c1_seq11,1698,41.9906,0.64739246,1,4,,8.00E-12,Q9H6Y5,PDZ domain-containing protein MAGIX,PDZ domain-containing protein MAGIX,,,PF00595;,,,,,,,,,MAGIX_HUMAN,Homo sapiens (Human), comp140817_c1_seq12,3831,44.0094,0.72304661,0,0,,6.00E-56,Q9JK71,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)",GO:0005524; GO:0005634; GO:0005886; GO:0005923,ATP binding; nucleus; plasma membrane; tight junction,PF00625;PF00595;PF00397;,2.00E-51,CHOYP_MAGI1.1.1,,,,,,,MAGI3_RAT,Rattus norvegicus (Rat),regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165] comp140817_c1_seq13,2526,44.8535,0.70535244,0,0,,2.00E-40,Q86UL8,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)",GO:0046332; GO:0060395; GO:0016482; GO:0030425; GO:0072015; GO:0005770; GO:0071850; GO:0032926; GO:0030336; GO:0008285; GO:0051898; GO:0038180; GO:0005634; GO:0048471; GO:0003402; GO:0005886; GO:0010976; GO:0032516; GO:0002092; GO:0014069; GO:0043234; GO:0051291; GO:0043113; GO:0030159; GO:0004871; GO:0036057; GO:0005923; GO:0070699,SMAD binding; SMAD protein signal transduction; cytoplasmic transport; dendrite; glomerular visceral epithelial cell development; late endosome; mitotic cell cycle arrest; negative regulation of activin receptor signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase B signaling cascade; nerve growth factor signaling pathway; nucleus; perinuclear region of cytoplasm; planar cell polarity pathway involved in axis elongation; plasma membrane; positive regulation of neuron projection development; positive regulation of phosphoprotein phosphatase activity; positive regulation of receptor internalization; postsynaptic density; protein complex; protein heterooligomerization; receptor clustering; receptor signaling complex scaffold activity; signal transducer activity; slit diaphragm; tight junction; type II activin receptor binding,PF00625;PF00595;PF00397;,,,,,,,,,MAGI2_HUMAN,Homo sapiens (Human),cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; SMAD protein signal transduction [GO:0060395] comp140817_c1_seq16,1186,43.8449,0.85202914,0,0,,9.00E-10,Q4R989,PDZ domain-containing protein 9,PDZ domain-containing protein 9,,,,,,,,,,,,PDZD9_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp140817_c1_seq17,4349,44.9069,0.6990198,0,0,,3.00E-25,P31016,Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90),Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90),GO:0033130; GO:0097113; GO:0032281; GO:0030054; GO:0032839; GO:0060997; GO:0007204; GO:0005783; GO:0045184; GO:0060076; GO:0031234; GO:0044224; GO:0035641; GO:0002091; GO:0050885; GO:0044306; GO:0045161; GO:0097481; GO:2000463; GO:0050806; GO:0045211; GO:0006461; GO:0097120; GO:2000310; GO:2000821; GO:0048169; GO:0097110; GO:0035176; GO:0008021; GO:0016188; GO:0071625,acetylcholine receptor binding; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; cell junction; dendrite cytoplasm; dendritic spine morphogenesis; elevation of cytosolic calcium ion concentration; endoplasmic reticulum; establishment of protein localization; excitatory synapse; extrinsic to internal side of plasma membrane; juxtaparanode region of axon; locomotory exploration behavior; negative regulation of receptor internalization; neuromuscular process controlling balance; neuron projection terminus; neuronal ion channel clustering; neuronal postsynaptic density; positive regulation of excitatory postsynaptic membrane potential; positive regulation of synaptic transmission; postsynaptic membrane; protein complex assembly; receptor localization to synapse; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of grooming behavior; regulation of long-term neuronal synaptic plasticity; scaffold protein binding; social behavior; synaptic vesicle; synaptic vesicle maturation; vocalization behavior,PF00625;PF10608;PF00595;PF10600;PF00018;,2.00E-51,CHOYP_MAGI1.1.1,,,,,,,DLG4_RAT,Rattus norvegicus (Rat),AMPA glutamate receptor clustering [GO:0097113]; dendritic spine morphogenesis [GO:0060997]; establishment of protein localization [GO:0045184]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission [GO:0050806]; protein complex assembly [GO:0006461]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625] comp140817_c1_seq18,5482,44.7282,0.70811022,0,6,,1.00E-144,Q9WVQ1,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)",GO:0030165; GO:0060395; GO:0031697; GO:0016482; GO:0030425; GO:0072015; GO:0005770; GO:0071850; GO:0032926; GO:0030336; GO:0008285; GO:0051898; GO:0038180; GO:0005634; GO:0048471; GO:0019902; GO:0005886; GO:0010976; GO:0032516; GO:0002092; GO:0014069; GO:0043234; GO:0051291; GO:0043113; GO:0030159; GO:0004871; GO:0036057; GO:0005923,PDZ domain binding; SMAD protein signal transduction; beta-1 adrenergic receptor binding; cytoplasmic transport; dendrite; glomerular visceral epithelial cell development; late endosome; mitotic cell cycle arrest; negative regulation of activin receptor signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase B signaling cascade; nerve growth factor signaling pathway; nucleus; perinuclear region of cytoplasm; phosphatase binding; plasma membrane; positive regulation of neuron projection development; positive regulation of phosphoprotein phosphatase activity; positive regulation of receptor internalization; postsynaptic density; protein complex; protein heterooligomerization; receptor clustering; receptor signaling complex scaffold activity; signal transducer activity; slit diaphragm; tight junction,PF00625;PF00595;PF00397;,,,,,,,,,MAGI2_MOUSE,Mus musculus (Mouse),cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] comp140817_c1_seq2,2356,45.3735,0.7463901,0,0,,2.00E-09,Q9HAP6,Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2),Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2),GO:0016323; GO:0006887; GO:0043005; GO:0007269; GO:0014069; GO:0045211; GO:0015031; GO:0005923,basolateral plasma membrane; exocytosis; neuron projection; neurotransmitter secretion; postsynaptic density; postsynaptic membrane; protein transport; tight junction,PF02828;PF00595;,,,,,,,,,LIN7B_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031] comp140817_c1_seq20,586,46.9283,0.53153452,4,0,,6.00E-39,Q5TCQ9,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)",GO:0005524; GO:0006915; GO:0004385; GO:0035556; GO:0016020; GO:0019048; GO:0005634; GO:0005886; GO:0043507; GO:0005923,ATP binding; apoptotic process; guanylate kinase activity; intracellular signal transduction; membrane; modulation by virus of host morphology or physiology; nucleus; plasma membrane; positive regulation of JUN kinase activity; tight junction,PF00625;PF00595;PF00397;,,,,,,,,,MAGI3_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; regulation of JNK cascade [GO:0046328]; viral process [GO:0016032] comp140817_c1_seq21,3842,43.9875,0.72182167,0,0,,6.00E-56,Q9JK71,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)",GO:0005524; GO:0005634; GO:0005886; GO:0005923,ATP binding; nucleus; plasma membrane; tight junction,PF00625;PF00595;PF00397;,2.00E-51,CHOYP_MAGI1.1.1,,,,,,,MAGI3_RAT,Rattus norvegicus (Rat),regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165] comp140817_c1_seq3,2689,46.0766,0.74700699,0,0,,4.00E-10,Q6R005,Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95),Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95),GO:0030054; GO:0014069; GO:0045211; GO:0050808; GO:0007268,cell junction; postsynaptic density; postsynaptic membrane; synapse organization; synaptic transmission,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,,,,,,,,,DLG4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808] comp140817_c1_seq4,2881,45.5745,0.72028131,0,0,,3.00E-09,Q4R989,PDZ domain-containing protein 9,PDZ domain-containing protein 9,,,,,,,,,,,,PDZD9_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp140817_c1_seq5,4163,45.5201,0.698489,0,0,,1.00E-151,Q9WVQ1,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)",GO:0030165; GO:0060395; GO:0031697; GO:0016482; GO:0030425; GO:0072015; GO:0005770; GO:0071850; GO:0032926; GO:0030336; GO:0008285; GO:0051898; GO:0038180; GO:0005634; GO:0048471; GO:0019902; GO:0005886; GO:0010976; GO:0032516; GO:0002092; GO:0014069; GO:0043234; GO:0051291; GO:0043113; GO:0030159; GO:0004871; GO:0036057; GO:0005923,PDZ domain binding; SMAD protein signal transduction; beta-1 adrenergic receptor binding; cytoplasmic transport; dendrite; glomerular visceral epithelial cell development; late endosome; mitotic cell cycle arrest; negative regulation of activin receptor signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase B signaling cascade; nerve growth factor signaling pathway; nucleus; perinuclear region of cytoplasm; phosphatase binding; plasma membrane; positive regulation of neuron projection development; positive regulation of phosphoprotein phosphatase activity; positive regulation of receptor internalization; postsynaptic density; protein complex; protein heterooligomerization; receptor clustering; receptor signaling complex scaffold activity; signal transducer activity; slit diaphragm; tight junction,PF00625;PF00595;PF00397;,3.00E-24,CHOYP_MAGI1.1.1,,,,,,,MAGI2_MOUSE,Mus musculus (Mouse),cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] comp140817_c1_seq7,3030,46.1056,0.68753977,0,0,,3.00E-08,Q8NI35,InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions),InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions),GO:0016324; GO:0035556; GO:0048471; GO:0005886; GO:0005923; GO:0070830,apical plasma membrane; intracellular signal transduction; perinuclear region of cytoplasm; plasma membrane; tight junction; tight junction assembly,PF09045;PF00595;,,,,,,,,,INADL_HUMAN,Homo sapiens (Human),bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556] comp140817_c1_seq8,2700,46.037,0.74539453,0,0,,3.00E-09,Q4R989,PDZ domain-containing protein 9,PDZ domain-containing protein 9,,,,,,,,,,,,PDZD9_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp140822_c0_seq1,2544,38.2862,0.48098696,31,152,,3.00E-104,Q6ING2,Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.-) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase),Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.-) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase),GO:0003723; GO:0009982; GO:0001522; GO:0008033,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; tRNA processing,,,,,,,,,,PUS10_XENLA,Xenopus laevis (African clawed frog),pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033] comp140822_c0_seq2,2556,38.2629,0.50102025,21,297,,1.00E-117,Q9D3U0,Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.-) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase),Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.-) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase),GO:0003723; GO:0009982; GO:0001522; GO:0008033,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; tRNA processing,,1.00E-32,CHOYP_PUS10.1.1,,,,,,,PUS10_MOUSE,Mus musculus (Mouse),tRNA pseudouridine synthesis [GO:0031119] comp140823_c1_seq1,1220,39.0984,0.58116247,1557,8277,,3.00E-138,P84173,Prohibitin,Prohibitin,GO:0006260; GO:0071354; GO:0016575; GO:0005887; GO:0005743; GO:0060766; GO:0030308; GO:0008285; GO:2000323; GO:0010944; GO:0005654; GO:0045893; GO:0050847; GO:0044212,"DNA replication; cellular response to interleukin-6; histone deacetylation; integral to plasma membrane; mitochondrial inner membrane; negative regulation of androgen receptor signaling pathway; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of glucocorticoid receptor signaling pathway; negative regulation of transcription by competitive promoter binding; nucleoplasm; positive regulation of transcription, DNA-dependent; progesterone receptor signaling pathway; transcription regulatory region DNA binding",PF01145;,1.00E-98,CHOYP_EF2.1.5,3.00E-78,ruditapes2_c2401,,,,,PHB_CHICK,Gallus gallus (Chicken),"cellular response to interleukin-6 [GO:0071354]; DNA biosynthetic process [GO:0071897]; histone deacetylation [GO:0016575]; mitochondrion organization [GO:0007005]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of complement activation [GO:0045917]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of transcription, DNA-templated [GO:0045893]; progesterone receptor signaling pathway [GO:0050847]; protein stabilization [GO:0050821]" comp140824_c0_seq1,5442,40.1139,0.47577767,0,0,,2.00E-88,Q9JKB5,AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF08169;,5.00E-60,CHOYP_ARI4B.1.1,,,,,,,ARI4B_RAT,Rattus norvegicus (Rat),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp140824_c0_seq2,5366,40.1789,0.46664805,0,0,,1.00E-88,Q9JKB5,AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF08169;,,,,,,,,,ARI4B_RAT,Rattus norvegicus (Rat),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp140824_c0_seq3,1592,42.4623,0.55860082,0,11,,4.00E-95,Q4LE39,AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),GO:0003677; GO:0005737; GO:0036124; GO:0034773; GO:0005634; GO:0006349; GO:0006355; GO:0006351,"DNA binding; cytoplasm; histone H3-K9 trimethylation; histone H4-K20 trimethylation; nucleus; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF08169;PF11717;,2.00E-60,CHOYP_ARI4B.1.1,,,,,,,ARI4B_HUMAN,Homo sapiens (Human),"establishment of Sertoli cell barrier [GO:0097368]; histone H3-K9 trimethylation [GO:0036124]; histone H4-K20 trimethylation [GO:0034773]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp140824_c0_seq4,5463,40.1245,0.47834552,0,0,,6.00E-11,Q5ZJ69,AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B),AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B),GO:0060612; GO:0005634; GO:0051091; GO:0044212; GO:0006351,"adipose tissue development; nucleus; positive regulation of sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",PF01388;,,,,,,,,,ARI5B_CHICK,Gallus gallus (Chicken),"adipose tissue development [GO:0060612]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp140824_c0_seq5,5387,40.1893,0.46928432,0,0,,2.00E-88,Q9JKB5,AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF08169;,5.00E-60,CHOYP_ARI4B.1.1,,,,,,,ARI4B_RAT,Rattus norvegicus (Rat),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp140829_c0_seq1,2065,39.2252,0.43488015,5,29,,,,,,,,,1.00E-13,CHOYP_LOC100367974.3.3,,,,,,,,, comp140829_c0_seq3,611,46.8085,0.38923783,0,0,,6.00E-07,P54787,Vacuolar protein sorting-associated protein 9 (Vacuolar protein-targeting protein 9),Vacuolar protein sorting-associated protein 9 (Vacuolar protein-targeting protein 9),GO:0006895; GO:0005829; GO:0005085; GO:0032511; GO:0036010; GO:0006623; GO:0043130; GO:0000011,Golgi to endosome transport; cytosol; guanyl-nucleotide exchange factor activity; late endosome to vacuole transport via multivesicular body sorting pathway; protein localization to endosome; protein targeting to vacuole; ubiquitin binding; vacuole inheritance,PF02845;PF02204;,3.00E-14,CHOYP_LOC100367974.3.3,,,,,,,VPS9_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),Golgi to endosome transport [GO:0006895]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein localization to endosome [GO:0036010]; protein targeting to vacuole [GO:0006623]; vacuole inheritance [GO:0000011] comp140829_c0_seq5,2099,39.2568,0.4264215,6,32,,1.00E-44,Q8C190,VPS9 domain-containing protein 1 (5-day ovary-specific transcript 1 protein),VPS9 domain-containing protein 1 (5-day ovary-specific transcript 1 protein),GO:0005737; GO:0005634,cytoplasm; nucleus,PF02204;,,,,,,,,,CP007_MOUSE,Mus musculus (Mouse), comp140830_c1_seq2,1688,44.9052,0.50971699,50,0,,2.00E-06,O73705,Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CHCACHA1A) (Voltage-gated calcium channel subunit alpha Cav2.1) (Fragment),Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CHCACHA1A) (Voltage-gated calcium channel subunit alpha Cav2.1) (Fragment),GO:0005245; GO:0005891,voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF00520;,,,,,,,,,CAC1A_CHICK,Gallus gallus (Chicken), comp140830_c1_seq3,1900,42,0.55353993,0,0,,2.00E-171,Q9W0Y8,Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2),Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2),GO:0042048; GO:0005886; GO:0007608; GO:0005248; GO:0001518,olfactory behavior; plasma membrane; sensory perception of smell; voltage-gated sodium channel activity; voltage-gated sodium channel complex,PF16905;PF00520;,5.00E-156,CHOYP_SCN1.2.2,,,,,,,SCN60_DROME,Drosophila melanogaster (Fruit fly),membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] comp140830_c1_seq8,1386,45.1659,0.49715833,0,0,,5.00E-10,Q91ZR5,Cation channel sperm-associated protein 1 (CatSper1),Cation channel sperm-associated protein 1 (CatSper1),GO:0036128; GO:0030154; GO:0001539; GO:0005929; GO:0007342; GO:0007275; GO:0051924; GO:0030317; GO:0007283; GO:0005245,CatSper complex; cell differentiation; ciliary or bacterial-type flagellar motility; cilium; fusion of sperm to egg plasma membrane; multicellular organismal development; regulation of calcium ion transport; sperm motility; spermatogenesis; voltage-gated calcium channel activity,PF00520;,,,,,,,,,CTSR1_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; fusion of sperm to egg plasma membrane [GO:0007342]; membrane depolarization during action potential [GO:0086010]; multicellular organism development [GO:0007275]; regulation of calcium ion transport [GO:0051924]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp140830_c1_seq9,1598,40.7384,0.591167,0,0,,4.00E-168,Q9W0Y8,Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2),Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2),GO:0042048; GO:0005886; GO:0007608; GO:0005248; GO:0001518,olfactory behavior; plasma membrane; sensory perception of smell; voltage-gated sodium channel activity; voltage-gated sodium channel complex,PF16905;PF00520;,5.00E-156,CHOYP_SCN1.2.2,,,,,,,SCN60_DROME,Drosophila melanogaster (Fruit fly),membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] comp140831_c1_seq3,1635,39.3272,0.41751095,17,96,,3.00E-71,Q6NZP1,DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],GO:0005524; GO:0003677; GO:0006281; GO:0036292; GO:0070530; GO:0036310; GO:0004520; GO:0004386; GO:0045910; GO:0043596; GO:0031297; GO:0048478; GO:0009411; GO:0008270,ATP binding; DNA binding; DNA repair; DNA rewinding; K63-linked polyubiquitin binding; annealing helicase activity; endodeoxyribonuclease activity; helicase activity; negative regulation of DNA recombination; nuclear replication fork; replication fork processing; replication fork protection; response to UV; zinc ion binding,PF00271;PF01844;PF00176;,6.00E-28,CHOYP_ZRANB3.1.1,,,,,,,ZRAB3_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411] comp140831_c1_seq4,509,37.1316,0.35631251,3,0,,,,,,,,,2.00E-27,CHOYP_ZRANB3.1.1,,,,,,,,, comp140831_c2_seq1,5181,35.8618,0.61891583,0,0,,1.00E-162,Q17RY0,Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4),Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4),GO:0003723; GO:0000166; GO:0045202,RNA binding; nucleotide binding; synapse,PF16366;PF16367;,,,,,,,,,CPEB4_HUMAN,Homo sapiens (Human),cellular response to amino acid stimulus [GO:0071230]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of neuron apoptotic process [GO:0043524]; response to ischemia [GO:0002931] comp140831_c2_seq2,5233,35.7921,0.60949583,1,0,,8.00E-166,Q812E0,Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2),Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2),GO:0005737; GO:0033125; GO:0045900; GO:0000166; GO:0008187; GO:0005844,cytoplasm; negative regulation of GTP catabolic process; negative regulation of translational elongation; nucleotide binding; poly-pyrimidine tract binding; polysome,PF16366;PF16367;,0,CHOYP_LOC100378487.1.1,,,,,,,CPEB2_MOUSE,Mus musculus (Mouse),cellular response to arsenic-containing substance [GO:0071243]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of GTPase activity [GO:0034260]; negative regulation of translational elongation [GO:0045900] comp140831_c2_seq3,3419,39.8362,0.62091509,0,0,,5.00E-80,Q6E3C9,Cytoplasmic polyadenylation element-binding protein 1,Cytoplasmic polyadenylation element-binding protein 1,GO:0003723; GO:0030154; GO:0007275; GO:0000166; GO:0007283,RNA binding; cell differentiation; multicellular organismal development; nucleotide binding; spermatogenesis,PF16366;PF16367;,,,,,,,,,CPB1_CAERE,Caenorhabditis remanei (Caenorhabditis vulgaris),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp140831_c2_seq4,5157,35.796,0.61764035,0,0,,6.00E-166,Q812E0,Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2),Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2),GO:0005737; GO:0033125; GO:0045900; GO:0000166; GO:0008187; GO:0005844,cytoplasm; negative regulation of GTP catabolic process; negative regulation of translational elongation; nucleotide binding; poly-pyrimidine tract binding; polysome,PF16366;PF16367;,0,CHOYP_LOC100378487.1.1,,,,,,,CPEB2_MOUSE,Mus musculus (Mouse),cellular response to arsenic-containing substance [GO:0071243]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of GTPase activity [GO:0034260]; negative regulation of translational elongation [GO:0045900] comp140831_c2_seq6,5258,35.8501,0.61095168,5,12,,2.00E-162,Q17RY0,Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4),Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4),GO:0003723; GO:0000166; GO:0045202,RNA binding; nucleotide binding; synapse,PF16366;PF16367;,,,,,,,,,CPEB4_HUMAN,Homo sapiens (Human),cellular response to amino acid stimulus [GO:0071230]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of neuron apoptotic process [GO:0043524]; response to ischemia [GO:0002931] comp140831_c2_seq7,3443,39.9071,0.62196052,0,0,,2.00E-169,Q812E0,Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2),Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2),GO:0005737; GO:0033125; GO:0045900; GO:0000166; GO:0008187; GO:0005844,cytoplasm; negative regulation of GTP catabolic process; negative regulation of translational elongation; nucleotide binding; poly-pyrimidine tract binding; polysome,PF16366;PF16367;,0,CHOYP_LOC100378487.1.1,1.00E-75,ruditapes_c21908,,,,,CPEB2_MOUSE,Mus musculus (Mouse),cellular response to arsenic-containing substance [GO:0071243]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of GTPase activity [GO:0034260]; negative regulation of translational elongation [GO:0045900] comp140832_c2_seq2,1115,36.2332,1.00119698,519,113,,6.00E-06,Q20681,BTB and MATH domain-containing protein 38,BTB and MATH domain-containing protein 38,,,PF00651;PF00917;,,,,,,,,,BAT38_CAEEL,Caenorhabditis elegans, comp140833_c0_seq3,2713,32.7682,0.44254215,56,276,,1.00E-88,P62744,AP-2 complex subunit sigma (Adapter-related protein complex 2 subunit sigma) (Adaptor protein complex AP-2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin),AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin),GO:0030121; GO:0030122; GO:0006886; GO:0008565; GO:0016192,AP-1 adaptor complex; AP-2 adaptor complex; intracellular protein transport; protein transporter activity; vesicle-mediated transport,PF01217;,8.00E-105,CHOYP_AP2S1.1.1,,,,,,,AP2S1_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] comp140834_c0_seq1,2613,45.8477,0.47413223,216,91,,0,Q9Y4D8,Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),GO:0005737; GO:0016021; GO:0005634; GO:0042787; GO:0004842,cytoplasm; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,4.00E-165,CHOYP_RGD1309762.1.1,,,,,,,HECD4_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp140834_c0_seq2,1526,45.9371,0.34988558,22,0,,3.00E-20,F8W2M1,E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1),E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1),GO:0032580; GO:0000139; GO:0007030; GO:0017137; GO:0007049; GO:0005783; GO:0061025; GO:0070936; GO:0042787; GO:0030334; GO:0004842,Golgi cisterna membrane; Golgi membrane; Golgi organization; Rab GTPase binding; cell cycle; endoplasmic reticulum; membrane fusion; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of cell migration; ubiquitin-protein ligase activity,PF12796;PF00632;,,,,,,,,,HACE1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell migration [GO:0030334] comp140834_c0_seq3,1926,45.9502,0.58080731,234,53,,1.00E-39,Q9Y4D8,Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),GO:0005737; GO:0016021; GO:0005634; GO:0042787; GO:0004842,cytoplasm; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,,,,,,,,,HECD4_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp140835_c1_seq1,1660,36.0843,0.44339617,2437,7489,,1.00E-19,Q8K194,U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (U4/U6.U5 tri-snRNP-associated protein 3),U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (U4/U6.U5 tri-snRNP-associated protein 3),GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF08648;,8.00E-27,CHOYP_PHUM_PHUM335250.2.2,,,,,,,SNR27_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp140836_c0_seq1,1701,41.2111,0.51854371,9,47,,3.00E-54,Q8BGA9,Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein),Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein),GO:0016021; GO:0005743; GO:0097031; GO:0097177; GO:0042803; GO:0051205; GO:0051262,integral to membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex I biogenesis; mitochondrial ribosome binding; protein homodimerization activity; protein insertion into membrane; protein tetramerization,PF02096;,,,,,,,,,OXA1L_MOUSE,Mus musculus (Mouse),aerobic respiration [GO:0009060]; mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex I biogenesis [GO:0097031]; negative regulation of ATPase activity [GO:0032780]; negative regulation of oxidoreductase activity [GO:0051354]; protein insertion into membrane [GO:0051205]; protein tetramerization [GO:0051262] comp140836_c0_seq2,1601,41.2242,0.49344777,0,10,,2.00E-50,Q3SYV3,Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein),Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein),GO:0016021; GO:0005743; GO:0031966; GO:0097031; GO:0097177; GO:0042803; GO:0051205; GO:0051262,integral to membrane; mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex I biogenesis; mitochondrial ribosome binding; protein homodimerization activity; protein insertion into membrane; protein tetramerization,PF02096;,,,,,,,,,OXA1L_BOVIN,Bos taurus (Bovine),mitochondrial respiratory chain complex I biogenesis [GO:0097031]; protein insertion into membrane [GO:0051205]; protein tetramerization [GO:0051262] comp140839_c0_seq1,286,37.7622,0.60063518,2,29,,,,,,,,,8.00E-11,CHOYP_BRAFLDRAFT_117821.1.1,,,,,,,,, comp140839_c1_seq3,313,42.492,0.79403109,3,87,,8.00E-25,P58200,Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1),Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1),GO:0005794; GO:0031201; GO:0016021; GO:0006886; GO:0031902; GO:0005765; GO:0016192,Golgi apparatus; SNARE complex; integral to membrane; intracellular protein transport; late endosome membrane; lysosomal membrane; vesicle-mediated transport,PF05008;,2.00E-18,CHOYP_BRAFLDRAFT_117821.1.1,,,,,,,VTI1B_RAT,Rattus norvegicus (Rat),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion with Golgi apparatus [GO:0048280]" comp140841_c1_seq1,3215,42.1773,0.38636393,6,68,,1.00E-151,Q5ZLV4,tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOL1/NOP2/Sun domain family member 2),tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOL1/NOP2/Sun domain family member 2),GO:0005737; GO:0005730; GO:0016428; GO:0000049,cytoplasm; nucleolus; tRNA (cytosine-5-)-methyltransferase activity; tRNA binding,PF01189;,5.00E-51,CHOYP_NSUN2.1.1,,,,,,,NSUN2_CHICK,Gallus gallus (Chicken),tRNA methylation [GO:0030488] comp140841_c1_seq2,3233,42.3136,0.39572171,65,351,,3.00E-132,Q9W4M9,tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog),tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog),GO:0005737; GO:0005730; GO:0007614; GO:0016428; GO:0000049,cytoplasm; nucleolus; short-term memory; tRNA (cytosine-5-)-methyltransferase activity; tRNA binding,PF01189;,5.00E-51,CHOYP_NSUN2.1.1,,,,,,,NSUN2_DROME,Drosophila melanogaster (Fruit fly),RNA methylation [GO:0001510]; short-term memory [GO:0007614]; tRNA methylation [GO:0030488] comp140843_c0_seq1,1291,35.0116,0.48564731,529,339,,1.00E-09,Q5RD08,Oxidative stress-responsive serine-rich protein 1 (Oxidative stress-responsive protein 1) (Peroxide-inducible transcript 1 protein),Oxidative stress-responsive serine-rich protein 1 (Oxidative stress-responsive protein 1) (Peroxide-inducible transcript 1 protein),,,PF05604;,5.00E-15,CHOYP_RL8.8.10,,,,,,,CT111_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140844_c1_seq2,703,45.9459,0.75961618,9,44,,,,,,,,,,,2.00E-26,ruditapes_c17324,,,,,,, comp140844_c2_seq2,1435,40.1394,0.91812579,12,380,,,,,,,,,8.00E-13,CHOYP_BRAFLDRAFT_129063.1.1,,,,,,,,, comp140847_c0_seq1,1643,36.8229,0.67028124,72,424,,4.00E-11,Q9XTR8,Lipase ZK262.3 (EC 3.1.1.-),Lipase ZK262.3 (EC 3.1.1.-),GO:0005576; GO:0016042; GO:0004806,extracellular region; lipid catabolic process; triglyceride lipase activity,PF01764;,,,,,,,,,LIP1_CAEEL,Caenorhabditis elegans,lipid catabolic process [GO:0016042] comp140848_c1_seq6,1946,38.4892,0.80715543,0,0,,3.00E-13,Q91Y77,Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1),Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1),GO:0016323; GO:0016021; GO:0055085,basolateral plasma membrane; integral to membrane; transmembrane transport,PF07690;,,,,,,,,,MOT10_RAT,Rattus norvegicus (Rat),ion transmembrane transport [GO:0034220] comp140848_c1_seq7,1956,38.5481,0.81410098,0,0,,6.00E-43,Q8R0M8,Monocarboxylate transporter 5 (MCT 5),Monocarboxylate transporter 5 (MCT 5),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT5_MOUSE,Mus musculus (Mouse),plasma membrane lactate transport [GO:0035879] comp140850_c1_seq2,2226,36.7925,0.43970261,8,19,,,,,,,,,6.00E-131,CHOYP_GPN3.1.2,,,,,,,,, comp140850_c1_seq3,2193,37.0725,0.44002683,15,64,,4.00E-122,Q6ZM63,GPN-loop GTPase 3 (ATP-binding domain 1 family member C),GPN-loop GTPase 3 (ATP-binding domain 1 family member C),GO:0005525,GTP binding,PF03029;,6.00E-131,CHOYP_GPN3.1.2,,,,,,,GPN3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140850_c1_seq6,266,35.7143,0.35823404,0,3,,1.00E-20,Q9UHW5,GPN-loop GTPase 3 (ATP-binding domain 1 family member C),GPN-loop GTPase 3 (ATP-binding domain 1 family member C),GO:0005525; GO:0043234,GTP binding; protein complex,PF03029;,,,,,,,,,GPN3_HUMAN,Homo sapiens (Human), comp140851_c0_seq1,650,43.3846,0.66700978,107,760,,6.00E-70,Q8WNV7,Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD),Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD),GO:0000253; GO:0004090; GO:0005739; GO:0005777; GO:0001758; GO:0042574,3-keto sterol reductase activity; carbonyl reductase (NADPH) activity; mitochondrion; peroxisome; retinal dehydrogenase activity; retinal metabolic process,,3.00E-40,CHOYP_LOC764565.1.1,3.00E-31,ruditapes_c14612,,,,,DHRS4_PIG,Sus scrofa (Pig),oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574] comp140851_c1_seq1,1102,34.2105,0.57183227,250,2028,,6.00E-17,P72332,Nodulation protein G,Nodulation protein G,GO:0004316; GO:0051287; GO:0006633; GO:0009877,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NAD binding; fatty acid biosynthetic process; nodulation,,,,,,,,,,NODG_RHIS3,Rhizobium sp. (strain N33),fatty acid biosynthetic process [GO:0006633]; nodulation [GO:0009877] comp140853_c0_seq1,580,46.2069,0.77812731,4,91,,3.00E-08,P13045,Protein GAL3,Protein GAL3,GO:0005524; GO:0005737; GO:0004335; GO:0006012; GO:0045185; GO:0005634; GO:0000435,ATP binding; cytoplasm; galactokinase activity; galactose metabolic process; maintenance of protein location; nucleus; positive regulation of transcription from RNA polymerase II promoter by galactose,PF10509;PF08544;PF00288;,3.00E-39,CHOYP_BRAFLDRAFT_90953.1.1,,,,,,,GAL3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),galactose metabolic process [GO:0006012]; maintenance of protein location [GO:0045185]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435] comp140853_c1_seq1,2349,37.6756,0.95871823,31,472,,5.00E-74,P51570,Galactokinase (EC 2.7.1.6) (Galactose kinase),Galactokinase (EC 2.7.1.6) (Galactose kinase),GO:0005524; GO:0005829; GO:0019402; GO:0004335; GO:0005534; GO:0019388; GO:0044281,ATP binding; cytosol; galactitol metabolic process; galactokinase activity; galactose binding; galactose catabolic process; small molecule metabolic process,PF10509;PF08544;PF00288;,,,,,,,,,GALK1_HUMAN,Homo sapiens (Human),galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] comp140856_c1_seq1,933,43.8371,0.76219366,246,310,,1.00E-94,Q02241,Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),GO:0005524; GO:0019886; GO:0007596; GO:0097149; GO:0005813; GO:0000910; GO:0005829; GO:0045171; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018; GO:0030496; GO:0000022; GO:0005654; GO:0032467; GO:0051256,ATP binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; centralspindlin complex; centrosome; cytokinesis; cytosol; intercellular bridge; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement; midbody; mitotic spindle elongation; nucleoplasm; positive regulation of cytokinesis; spindle midzone assembly involved in mitosis,PF00225;PF16540;,2.00E-87,CHOYP_LOC373240.1.1,,,,,,,KIF23_HUMAN,Homo sapiens (Human),"actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp140856_c1_seq2,268,42.9104,0.66916355,12,2,,2.00E-08,Q02241,Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),GO:0005524; GO:0019886; GO:0007596; GO:0097149; GO:0005813; GO:0000910; GO:0005829; GO:0045171; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018; GO:0030496; GO:0000022; GO:0005654; GO:0032467; GO:0051256,ATP binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; centralspindlin complex; centrosome; cytokinesis; cytosol; intercellular bridge; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement; midbody; mitotic spindle elongation; nucleoplasm; positive regulation of cytokinesis; spindle midzone assembly involved in mitosis,PF00225;PF16540;,,,,,,,,,KIF23_HUMAN,Homo sapiens (Human),"actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp140857_c0_seq1,1786,33.9306,0.31241269,118,733,,9.00E-23,P95957,Uncharacterized aminotransferase SSO0104 (EC 2.6.1.-) (AspB-1),Uncharacterized aminotransferase SSO0104 (EC 2.6.1.-) (AspB-1),GO:0009058; GO:0005737; GO:0030170; GO:0008483,biosynthetic process; cytoplasm; pyridoxal phosphate binding; transaminase activity,PF00155;,,,,,,,,,Y104_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2),biosynthetic process [GO:0009058] comp140857_c0_seq2,489,46.6258,0.56595293,21,177,,2.00E-14,Q8N5Z0,"Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)","Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)",GO:0047536; GO:0006103; GO:0033512; GO:0009058; GO:0006536; GO:0016212; GO:0006554; GO:0005759; GO:0030170; GO:0006569; GO:0019441,2-aminoadipate transaminase activity; 2-oxoglutarate metabolic process; L-lysine catabolic process to acetyl-CoA via saccharopine; biosynthetic process; glutamate metabolic process; kynurenine-oxoglutarate transaminase activity; lysine catabolic process; mitochondrial matrix; pyridoxal phosphate binding; tryptophan catabolic process; tryptophan catabolic process to kynurenine,PF00155;,,,,,,,,,AADAT_HUMAN,Homo sapiens (Human),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]; tryptophan catabolic process to kynurenine [GO:0019441] comp140858_c0_seq1,3160,37.1203,0.60912707,93,58,,7.00E-37,Q12116,Membrane protein TMS1,Membrane protein TMS1,GO:0016021; GO:0016020,integral to membrane; membrane,PF03348;,3.00E-143,CHOYP_LOC100120039.1.1,,,,,,,TMS1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp140858_c0_seq2,3101,37.375,0.61194411,0,0,,4.00E-132,Q5R533,Serine incorporator 3,Serine incorporator 3,GO:0000139; GO:0016021; GO:0005886,Golgi membrane; integral to membrane; plasma membrane,PF03348;,3.00E-143,CHOYP_LOC100120039.1.1,3.00E-45,ruditapes_c771,,,,,SERC3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; phosphatidylserine metabolic process [GO:0006658]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; sphingolipid metabolic process [GO:0006665] comp140858_c0_seq3,3174,37.1771,0.61351601,0,0,,2.00E-119,A7S4N4,Probable serine incorporator,Probable serine incorporator,GO:0005789; GO:0016021; GO:0008654,endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process,PF03348;,,,,,,,,,SERIC_NEMVE,Nematostella vectensis (Starlet sea anemone),phospholipid biosynthetic process [GO:0008654] comp140858_c0_seq4,3129,37.52,0.61990313,0,0,,1.00E-130,Q5R533,Serine incorporator 3,Serine incorporator 3,GO:0000139; GO:0016021; GO:0005886,Golgi membrane; integral to membrane; plasma membrane,PF03348;,,,,,,,,,SERC3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; phosphatidylserine metabolic process [GO:0006658]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; sphingolipid metabolic process [GO:0006665] comp140858_c0_seq5,3192,37.2494,0.61678755,0,0,,7.00E-67,Q4R6L9,Serine incorporator 5,Serine incorporator 5,GO:0005789; GO:0016021; GO:0008654,endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process,PF03348;,,,,,,,,,SERC5_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; myelination [GO:0042552]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; sphingolipid metabolic process [GO:0006665] comp140858_c0_seq6,3111,37.4478,0.61666417,0,0,,8.00E-129,Q7TNK0,Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2),Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2),GO:0015194; GO:0005789; GO:0016021; GO:0006658; GO:0008654; GO:0005886; GO:0051347; GO:0006665,L-serine transmembrane transporter activity; endoplasmic reticulum membrane; integral to membrane; phosphatidylserine metabolic process; phospholipid biosynthetic process; plasma membrane; positive regulation of transferase activity; sphingolipid metabolic process,PF03348;,8.00E-144,CHOYP_LOC100120039.1.1,,,,,,,SERC1_RAT,Rattus norvegicus (Rat),L-serine transport [GO:0015825]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222]; sphingolipid metabolic process [GO:0006665] comp140859_c0_seq1,1660,38.0723,0.64982418,271,796,,4.00E-41,A6QPN6,Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (IFI30 protein),Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (IFI30 protein),GO:0042590; GO:0005576; GO:0005764; GO:0016667,"antigen processing and presentation of exogenous peptide antigen via MHC class I; extracellular region; lysosome; oxidoreductase activity, acting on a sulfur group of donors",PF03227;,5.00E-16,CHOYP_BRAFLDRAFT_126371.1.3,,,,,,,GILT_BOVIN,Bos taurus (Bovine),antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] comp140862_c0_seq1,1932,47.6708,0.63692426,0,0,,1.00E-09,P19682,"28 kDa ribonucleoprotein, chloroplastic (28RNP)","28 kDa ribonucleoprotein, chloroplastic (28RNP)",GO:0003723; GO:0009507; GO:0006397; GO:0000166; GO:0030529,RNA binding; chloroplast; mRNA processing; nucleotide binding; ribonucleoprotein complex,PF00076;,,,,,,,,,ROC3_NICSY,Nicotiana sylvestris (Wood tobacco) (South American tobacco),mRNA processing [GO:0006397] comp140862_c0_seq2,1624,46.1207,0.6084,0,0,,4.00E-09,Q04836,"31 kDa ribonucleoprotein, chloroplastic (RNA-binding protein 1/2/3) (AtRBP33) (RNA-binding protein RNP-T) (RNA-binding protein cp31)","31 kDa ribonucleoprotein, chloroplastic (RNA-binding protein 1/2/3) (AtRBP33) (RNA-binding protein CP31A) (RNA-binding protein RNP-T) (RNA-binding protein cp31)",GO:0006396; GO:0043489; GO:0016553; GO:0009941; GO:0009570; GO:0009535; GO:0009631; GO:0045087; GO:0006397; GO:0000166; GO:0008266; GO:0030529,RNA processing; RNA stabilization; base conversion or substitution editing; chloroplast envelope; chloroplast stroma; chloroplast thylakoid membrane; cold acclimation; innate immune response; mRNA processing; nucleotide binding; poly(U) RNA binding; ribonucleoprotein complex,PF00076;,,,,,,,,,ROC3_ARATH,Arabidopsis thaliana (Mouse-ear cress),base conversion or substitution editing [GO:0016553]; cold acclimation [GO:0009631]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; RNA modification [GO:0009451]; RNA processing [GO:0006396]; RNA stabilization [GO:0043489] comp140862_c0_seq4,1717,46.7676,0.56498166,0,0,,6.00E-22,Q7ZWA3,"RNA-binding motif protein, X chromosome (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G)","RNA-binding motif protein, X chromosome (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G)",GO:0008380; GO:0071013; GO:0071347; GO:0003682; GO:0001047; GO:0070062; GO:0003729; GO:0006397; GO:0006509; GO:0007275; GO:0048025; GO:0005719; GO:0000166; GO:0048026; GO:0045944; GO:0051260; GO:0000381; GO:0044530; GO:0006366,"RNA splicing; catalytic step 2 spliceosome; cellular response to interleukin-1; chromatin binding; core promoter binding; extracellular vesicular exosome; mRNA binding; mRNA processing; membrane protein ectodomain proteolysis; multicellular organismal development; negative regulation of mRNA splicing, via spliceosome; nuclear euchromatin; nucleotide binding; positive regulation of mRNA splicing, via spliceosome; positive regulation of transcription from RNA polymerase II promoter; protein homooligomerization; regulation of alternative mRNA splicing, via spliceosome; supraspliceosomal complex; transcription from RNA polymerase II promoter",PF08081;PF00076;,,,,,,,,,RBMX_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]" comp140862_c0_seq5,1567,47.1602,0.59923591,0,0,,8.00E-10,P19682,"28 kDa ribonucleoprotein, chloroplastic (28RNP)","28 kDa ribonucleoprotein, chloroplastic (28RNP)",GO:0003723; GO:0009507; GO:0006397; GO:0000166; GO:0030529,RNA binding; chloroplast; mRNA processing; nucleotide binding; ribonucleoprotein complex,PF00076;,,,,,,,,,ROC3_NICSY,Nicotiana sylvestris (Wood tobacco) (South American tobacco),mRNA processing [GO:0006397] comp140862_c0_seq6,1839,47.1452,0.67859139,0,0,,5.00E-22,Q7ZWA3,"RNA-binding motif protein, X chromosome (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G)","RNA-binding motif protein, X chromosome (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G)",GO:0008380; GO:0071013; GO:0071347; GO:0003682; GO:0001047; GO:0070062; GO:0003729; GO:0006397; GO:0006509; GO:0007275; GO:0048025; GO:0005719; GO:0000166; GO:0048026; GO:0045944; GO:0051260; GO:0000381; GO:0044530; GO:0006366,"RNA splicing; catalytic step 2 spliceosome; cellular response to interleukin-1; chromatin binding; core promoter binding; extracellular vesicular exosome; mRNA binding; mRNA processing; membrane protein ectodomain proteolysis; multicellular organismal development; negative regulation of mRNA splicing, via spliceosome; nuclear euchromatin; nucleotide binding; positive regulation of mRNA splicing, via spliceosome; positive regulation of transcription from RNA polymerase II promoter; protein homooligomerization; regulation of alternative mRNA splicing, via spliceosome; supraspliceosomal complex; transcription from RNA polymerase II promoter",PF08081;PF00076;,,,,,,,,,RBMX_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]" comp140863_c0_seq1,1084,48.6162,0.39129026,81,46,,6.00E-26,Q402B2,WD repeat-containing protein 93 (Protein MA0035),WD repeat-containing protein 93 (Protein MA0035),GO:0022900; GO:0016651,"electron transport chain; oxidoreductase activity, acting on NAD(P)H",,,,,,,,,,WDR93_MOUSE,Mus musculus (Mouse),electron transport chain [GO:0022900] comp140864_c0_seq1,269,44.9814,0.30822344,0,4,,,,,,,,,4.00E-14,CHOYP_LOC755638.1.1,,,,,,,,, comp140864_c0_seq3,2217,40.4601,0.47864107,12,156,,9.00E-134,Q2TAQ1,Putative elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein),Putative elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein),GO:0005737; GO:0008607; GO:0006357; GO:0008023; GO:0006351,"cytoplasm; phosphorylase kinase regulator activity; regulation of transcription from RNA polymerase II promoter; transcription elongation factor complex; transcription, DNA-dependent",PF04762;,,,,,,,,,ELP1_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]" comp140864_c0_seq4,1702,39.953,0.50791246,12,81,,5.00E-59,Q7TT37,Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein),Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein),GO:0003677; GO:0016591; GO:0033588; GO:0005737; GO:0005730; GO:0008607; GO:0030335; GO:0006357; GO:0008023; GO:0006368,"DNA binding; DNA-directed RNA polymerase II, holoenzyme; Elongator holoenzyme complex; cytoplasm; nucleolus; phosphorylase kinase regulator activity; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; transcription elongation factor complex; transcription elongation from RNA polymerase II promoter",PF04762;,,,,,,,,,ELP1_MOUSE,Mus musculus (Mouse),"positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]" comp140864_c1_seq2,418,47.6077,0.5107709,14,43,,3.00E-22,O59704,Elongator complex protein 1 (Protein iki3),Elongator complex protein 1 (Protein iki3),GO:0033588; GO:0005829; GO:0015031; GO:0006355; GO:0002098; GO:0006351,"Elongator holoenzyme complex; cytosol; protein transport; regulation of transcription, DNA-dependent; tRNA wobble uridine modification; transcription, DNA-dependent",PF04762;,6.00E-46,CHOYP_ELP1.2.2,,,,,,,ELP1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]" comp140866_c0_seq1,2184,48.7179,0.52460995,0,0,,2.00E-138,Q6P5D4,Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),GO:0005814; GO:0007099; GO:0010457,centriole; centriole replication; centriole-centriole cohesion,,,,,,,,,,CP135_MOUSE,Mus musculus (Mouse),centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp140866_c0_seq2,2754,47.5672,0.59841962,0,0,,1.00E-156,Q66GS9,Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),GO:0000086; GO:0005814; GO:0007099; GO:0010457; GO:0005829,G2/M transition of mitotic cell cycle; centriole; centriole replication; centriole-centriole cohesion; cytosol,,0,CHOYP_LOC576511.1.1,,,,,,,CP135_HUMAN,Homo sapiens (Human),centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp140866_c0_seq5,2775,47.4595,0.60352066,0,0,,2.00E-155,Q6P5D4,Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),GO:0005814; GO:0007099; GO:0010457,centriole; centriole replication; centriole-centriole cohesion,,,,,,,,,,CP135_MOUSE,Mus musculus (Mouse),centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp140866_c0_seq6,2802,47.3947,0.59952125,0,0,,5.00E-138,Q5RG45,Centrosomal protein of 135 kDa (Cep135),Centrosomal protein of 135 kDa (Cep135),GO:0005814; GO:0007099; GO:0010457,centriole; centriole replication; centriole-centriole cohesion,,0,CHOYP_LOC576511.1.1,,,,,,,CP135_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099] comp140866_c0_seq8,2479,46.0266,0.62104034,0,0,,2.00E-150,Q66GS9,Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4),GO:0000086; GO:0005814; GO:0007099; GO:0010457; GO:0005829,G2/M transition of mitotic cell cycle; centriole; centriole replication; centriole-centriole cohesion; cytosol,,0,CHOYP_LOC576511.1.1,,,,,,,CP135_HUMAN,Homo sapiens (Human),centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp140867_c0_seq2,2157,36.764,1.18752025,68,318,,,,,,,,,,,8.00E-51,ruditapes_c19959,,,,,,, comp140868_c0_seq1,2244,38.8146,0.52222009,488,2111,,1.00E-137,Q2YDD0,Heat shock 70 kDa protein 14,Heat shock 70 kDa protein 14,GO:0005524; GO:0005829; GO:0005840,ATP binding; cytosol; ribosome,PF00012;,2.00E-28,CHOYP_HSP7E.1.1,,,,,,,HSP7E_BOVIN,Bos taurus (Bovine), comp140868_c0_seq2,814,39.8034,0.62801097,12,89,,2.00E-32,Q4R6J2,Heat shock 70 kDa protein 14,Heat shock 70 kDa protein 14,GO:0005524; GO:0005829,ATP binding; cytosol,PF00012;,,,,,,,,,HSP7E_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp140870_c0_seq3,2164,39.3253,0.7302866,0,0,,6.00E-22,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,4.00E-25,CHOYP_LOC100892023.1.1,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp140870_c0_seq9,2058,39.553,0.74667748,0,0,,6.00E-22,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,4.00E-25,CHOYP_LOC100892023.1.1,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp140871_c1_seq6,241,26.971,0.23359476,1,7,,,,,,,,,6.00E-18,CHOYP_NEMVEDRAFT_V1G197092.1.2,,,,,,,,, comp140871_c1_seq7,247,23.8866,0.29176949,5,0,,,,,,,,,,,9.00E-14,ruditapes_c26162,,,,,,, comp140872_c1_seq1,2224,42.536,0.3599936,167,291,,2.00E-45,Q9Y6J0,Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),GO:0016235; GO:0007166; GO:0016568; GO:0005737; GO:0005634; GO:0004864,aggresome; cell surface receptor signaling pathway; chromatin modification; cytoplasm; nucleus; protein phosphatase inhibitor activity,PF09047;,,,,,,,,,CABIN_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823] comp140873_c0_seq1,1466,41.8145,0.68010425,11,54,,4.00E-146,Q6PCB7,Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1),Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1),GO:0033211; GO:0032049; GO:0012505; GO:0005783; GO:0006631; GO:0015245; GO:0016021; GO:0015909; GO:0001579; GO:0071072; GO:0000166; GO:0006654; GO:0006656; GO:0006646; GO:0006661; GO:0006659; GO:0005886; GO:0031652; GO:0071902; GO:0009409; GO:0032868; GO:0055085; GO:0031957,adiponectin-mediated signaling pathway; cardiolipin biosynthetic process; endomembrane system; endoplasmic reticulum; fatty acid metabolic process; fatty acid transporter activity; integral to membrane; long-chain fatty acid transport; medium-chain fatty acid transport; negative regulation of phospholipid biosynthetic process; nucleotide binding; phosphatidic acid biosynthetic process; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylinositol biosynthetic process; phosphatidylserine biosynthetic process; plasma membrane; positive regulation of heat generation; positive regulation of protein serine/threonine kinase activity; response to cold; response to insulin stimulus; transmembrane transport; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,S27A1_HUMAN,Homo sapiens (Human),adiponectin-activated signaling pathway [GO:0033211]; cardiolipin biosynthetic process [GO:0032049]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of phospholipid biosynthetic process [GO:0071072]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphatidylglycerol biosynthetic process [GO:0006655]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylserine biosynthetic process [GO:0006659]; positive regulation of heat generation [GO:0031652]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to cold [GO:0009409]; response to insulin [GO:0032868] comp140873_c0_seq2,1839,39.5324,0.61010798,97,370,,8.00E-23,B2HHZ8,Long-chain-fatty-acid--CoA ligase FadD17 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase),Long-chain-fatty-acid--CoA ligase FadD17 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase),GO:0005524; GO:0006633; GO:0001676; GO:0004467,ATP binding; fatty acid biosynthetic process; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,4.00E-88,CHOYP_S27A4.2.2,,,,,,,FAC17_MYCMM,Mycobacterium marinum (strain ATCC BAA-535 / M),fatty acid biosynthetic process [GO:0006633] comp140873_c1_seq1,382,49.4764,0.3884408,28,74,,2.00E-08,A5JTM6,4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33),4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33),GO:0018861; GO:0005524,4-chlorobenzoate-CoA ligase activity; ATP binding,PF00501;PF13193;,,,,,,,,,CBACL_PSEUC,Pseudomonas sp. (strain CBS-3),metabolic process [GO:0008152] comp140873_c1_seq2,665,43.609,0.95799986,33,103,,2.00E-08,Q4WF61,Nonribosomal peptide synthetase 3 (EC 6.3.2.-) (Siderophore peptide synthase E),Nonribosomal peptide synthetase 3 (EC 6.3.2.-) (Siderophore peptide synthase E),GO:0010106; GO:0016853; GO:0016874; GO:0019184; GO:0009405; GO:0019748,cellular response to iron ion starvation; isomerase activity; ligase activity; nonribosomal peptide biosynthetic process; pathogenesis; secondary metabolic process,PF00501;PF13193;PF00668;PF00550;,,,,,,,,,NRPS3_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),cellular response to iron ion starvation [GO:0010106]; nonribosomal peptide biosynthetic process [GO:0019184]; pathogenesis [GO:0009405]; secondary metabolic process [GO:0019748] comp140877_c0_seq2,372,31.7204,0.21455433,17,46,,6.00E-08,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp140880_c1_seq3,301,35.2159,0.21502551,5,6,,,,,,,,,9.00E-11,CHOYP_contig_055724,,,,,,,,, comp140880_c1_seq9,2931,40.2593,0.37960594,149,501,,1.00E-07,Q9SMY8,F-box/LRR-repeat protein 15,F-box/LRR-repeat protein 15,,,PF12937;,,,,,,,,,FBL15_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp140885_c0_seq2,569,23.7258,0.37882261,7,29,,,,,,,,,,,3.00E-12,ruditapes_c16393,,,,,,, comp140887_c0_seq2,1574,35.0064,0.39568694,34,33,,6.00E-69,Q14181,DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit),DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit),GO:0003677; GO:0006270; GO:0006271; GO:0003887; GO:0000082; GO:0005658; GO:0005737; GO:0005654; GO:0000060; GO:0000722; GO:0032201,"DNA binding; DNA replication initiation; DNA strand elongation involved in DNA replication; DNA-directed DNA polymerase activity; G1/S transition of mitotic cell cycle; alpha DNA polymerase:primase complex; cytoplasm; nucleoplasm; protein import into nucleus, translocation; telomere maintenance via recombination; telomere maintenance via semi-conservative replication",PF04042;PF08418;,,,,,,,,,DPOA2_HUMAN,Homo sapiens (Human),"DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; G1/S transition of mitotic cell cycle [GO:0000082]; protein import into nucleus, translocation [GO:0000060]; telomere maintenance via recombination [GO:0000722]" comp140887_c0_seq3,1647,35.2155,0.45147475,31,125,,1.00E-68,Q14181,DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit),DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit),GO:0003677; GO:0006270; GO:0006271; GO:0003887; GO:0000082; GO:0005658; GO:0005737; GO:0005654; GO:0000060; GO:0000722; GO:0032201,"DNA binding; DNA replication initiation; DNA strand elongation involved in DNA replication; DNA-directed DNA polymerase activity; G1/S transition of mitotic cell cycle; alpha DNA polymerase:primase complex; cytoplasm; nucleoplasm; protein import into nucleus, translocation; telomere maintenance via recombination; telomere maintenance via semi-conservative replication",PF04042;PF08418;,,,,,,,,,DPOA2_HUMAN,Homo sapiens (Human),"DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; G1/S transition of mitotic cell cycle [GO:0000082]; protein import into nucleus, translocation [GO:0000060]; telomere maintenance via recombination [GO:0000722]" comp140887_c0_seq5,1128,44.1489,0.45819097,64,212,,7.00E-60,Q58D13,DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit),DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit),GO:0003677; GO:0006260; GO:0003887; GO:0005634,DNA binding; DNA replication; DNA-directed DNA polymerase activity; nucleus,PF04042;PF08418;,1.00E-29,CHOYP_LOC100372955.1.1,,,,,,,DPOA2_BOVIN,Bos taurus (Bovine),DNA replication initiation [GO:0006270] comp140890_c0_seq1,1433,41.8004,0.72385282,328,813,,2.00E-32,Q6GLJ1,BTB/POZ domain-containing protein 17,BTB/POZ domain-containing protein 17,GO:0005576,extracellular region,PF07707;PF00651;,,,,,,,,,BTBDH_XENLA,Xenopus laevis (African clawed frog), comp140895_c0_seq1,2664,35.6982,0.41282359,9,21,,2.00E-32,Q91VR8,Protein BRICK1 (BRK1),Protein BRICK1 (BRK1),GO:0030036; GO:0048870; GO:0005737; GO:0005856; GO:0001701; GO:0008284,actin cytoskeleton organization; cell motility; cytoplasm; cytoskeleton; in utero embryonic development; positive regulation of cell proliferation,,,,,,,,,,BRK1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell motility [GO:0048870]; in utero embryonic development [GO:0001701]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; protein homotrimerization [GO:0070207]; Rac protein signal transduction [GO:0016601] comp140895_c0_seq4,2993,34.9482,0.42689338,0,0,,2.00E-32,Q91VR8,Protein BRICK1 (BRK1),Protein BRICK1 (BRK1),GO:0030036; GO:0048870; GO:0005737; GO:0005856; GO:0001701; GO:0008284,actin cytoskeleton organization; cell motility; cytoplasm; cytoskeleton; in utero embryonic development; positive regulation of cell proliferation,,,,,,,,,,BRK1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell motility [GO:0048870]; in utero embryonic development [GO:0001701]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; protein homotrimerization [GO:0070207]; Rac protein signal transduction [GO:0016601] comp140896_c1_seq1,3537,42.4371,0.42864222,3,27,,4.00E-136,P20742,Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6),Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6),GO:0004866; GO:0005615; GO:0070062; GO:0007565; GO:0004867,endopeptidase inhibitor activity; extracellular space; extracellular vesicular exosome; female pregnancy; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,PZP_HUMAN,Homo sapiens (Human),female pregnancy [GO:0007565] comp140896_c1_seq2,2912,42.5824,0.46373856,20,11,,4.00E-89,Q8IZJ3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,GO:0005615; GO:0010951; GO:0005886; GO:0004867,extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;,,,,,,,,,CPMD8_HUMAN,Homo sapiens (Human), comp140898_c1_seq7,978,40.593,0.8945187,1,152,,2.00E-06,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp140899_c0_seq5,1329,39.6539,0.5939214,10,13,,2.00E-72,Q9QY40,Plexin-B3 (Plexin-6),Plexin-B3 (Plexin-6),GO:0016021; GO:0005622; GO:0007399; GO:0005886; GO:0004872; GO:0007165,integral to membrane; intracellular; nervous system development; plasma membrane; receptor activity; signal transduction,PF08337;PF01437;PF01403;PF01833;,6.00E-141,CHOYP_ISCW_ISCW007151.2.2,,,,,,,PLXB3_MOUSE,Mus musculus (Mouse),cell chemotaxis [GO:0060326]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of GTPase activity [GO:0034260]; negative regulation of lamellipodium assembly [GO:0010593]; positive chemotaxis [GO:0050918]; positive regulation of axonogenesis [GO:0050772]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp140899_c0_seq7,1341,39.5973,0.60923879,0,0,,1.00E-119,B0S5N4,Plexin A3,Plexin A3,GO:0048675; GO:0048755; GO:0060272; GO:0016021; GO:0005622; GO:0008045; GO:0005886; GO:0004872; GO:0048696; GO:0007165,axon extension; branching morphogenesis of a nerve; embryonic skeletal joint morphogenesis; integral to membrane; intracellular; motor neuron axon guidance; plasma membrane; receptor activity; regulation of collateral sprouting in absence of injury; signal transduction,PF08337;PF01437;PF01403;PF01833;,3.00E-37,CHOYP_LOC100168635.1.1,,,,,,,PLXA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp140899_c0_seq8,217,38.7097,0.24943321,3,0,,8.00E-12,O75051,Plexin-A2 (Semaphorin receptor OCT),Plexin-A2 (Semaphorin receptor OCT),GO:0007411; GO:0051642; GO:0021935; GO:0005887; GO:0005622; GO:0060174; GO:0021915; GO:0060037; GO:0030334; GO:0017154; GO:0002116; GO:0001756,axon guidance; centrosome localization; cerebellar granule cell precursor tangential migration; integral to plasma membrane; intracellular; limb bud formation; neural tube development; pharyngeal system development; regulation of cell migration; semaphorin receptor activity; semaphorin receptor complex; somitogenesis,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA2_HUMAN,Homo sapiens (Human),branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] comp140899_c0_seq9,548,33.3942,0.52460758,0,0,,1.00E-09,B0S5N4,Plexin A3,Plexin A3,GO:0048675; GO:0048755; GO:0060272; GO:0016021; GO:0005622; GO:0008045; GO:0005886; GO:0004872; GO:0048696; GO:0007165,axon extension; branching morphogenesis of a nerve; embryonic skeletal joint morphogenesis; integral to membrane; intracellular; motor neuron axon guidance; plasma membrane; receptor activity; regulation of collateral sprouting in absence of injury; signal transduction,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp140902_c1_seq1,2352,40.8588,0.76714527,18,132,,9.00E-88,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,1.00E-38,CHOYP_HSPA12A.16.27,8.00E-20,ruditapes_c7452,,,,,HS12A_HUMAN,Homo sapiens (Human), comp140902_c1_seq2,2509,39.4181,0.64422928,56,274,,3.00E-87,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,1.00E-38,CHOYP_HSPA12A.16.27,3.00E-88,ruditapes_c7506,,,,,HS12A_HUMAN,Homo sapiens (Human), comp140902_c1_seq3,271,44.2804,0.47566955,5,7,,,,,,,,,1.00E-13,CHOYP_BRAFLDRAFT_208436.17.32,,,,,,,,, comp140903_c2_seq1,2836,39.3159,0.51688448,31,207,,7.00E-36,B7KSZ5,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,0,CHOYP_DNJA2.2.2,,,,,,,DNAJ_METC4,Methylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp140903_c2_seq2,3023,39.3979,0.51501319,22,134,,8.00E-147,O60884,DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14),DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14),GO:0005524; GO:0016020; GO:0046872; GO:0008284; GO:0006457; GO:0009408,ATP binding; membrane; metal ion binding; positive regulation of cell proliferation; protein folding; response to heat,PF00226;PF01556;PF00684;,,,,,,,,,DNJA2_HUMAN,Homo sapiens (Human),carbon tetrachloride metabolic process [GO:0018885]; positive regulation of cell proliferation [GO:0008284]; protein refolding [GO:0042026]; response to heat [GO:0009408] comp140903_c2_seq3,3786,35.7369,0.53260635,57,723,,4.00E-106,Q5NVI9,DnaJ homolog subfamily A member 1,DnaJ homolog subfamily A member 1,GO:0005524; GO:0016020; GO:0046872; GO:0006457; GO:0009408,ATP binding; membrane; metal ion binding; protein folding; response to heat,PF00226;PF01556;PF00684;,1.00E-15,CHOYP_LOC100374573.1.1,,,,,,,DNJA1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408] comp140903_c2_seq6,2914,39.2931,0.49285505,8,46,,3.00E-147,O60884,DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14),DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14),GO:0005524; GO:0016020; GO:0046872; GO:0008284; GO:0006457; GO:0009408,ATP binding; membrane; metal ion binding; positive regulation of cell proliferation; protein folding; response to heat,PF00226;PF01556;PF00684;,,,,,,,,,DNJA2_HUMAN,Homo sapiens (Human),carbon tetrachloride metabolic process [GO:0018885]; positive regulation of cell proliferation [GO:0008284]; protein refolding [GO:0042026]; response to heat [GO:0009408] comp140903_c2_seq7,2738,39.2988,0.51664538,117,668,,2.00E-108,Q5NVI9,DnaJ homolog subfamily A member 1,DnaJ homolog subfamily A member 1,GO:0005524; GO:0016020; GO:0046872; GO:0006457; GO:0009408,ATP binding; membrane; metal ion binding; protein folding; response to heat,PF00226;PF01556;PF00684;,0,CHOYP_DNJA2.2.2,,,,,,,DNJA1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408] comp140903_c3_seq1,1763,33.2955,0.30723867,440,882,,3.00E-07,Q8ILR9,Protein PF14_0175,Protein PF14_0175,GO:0003677; GO:0016021,DNA binding; integral to membrane,,,,,,,,,,YPF17_PLAF7,Plasmodium falciparum (isolate 3D7), comp140904_c0_seq1,557,43.6266,0.71819768,25,1,,3.00E-10,Q9V4C8,Host cell factor (dHcf) [Cleaved into: HCF N-terminal chain; HCF C-terminal chain],Host cell factor (dHcf) [Cleaved into: HCF N-terminal chain; HCF C-terminal chain],GO:0044666; GO:0048188; GO:0007049; GO:0003682; GO:0006338; GO:0043966; GO:0051568; GO:0043967; GO:0000123; GO:0045927; GO:0045893; GO:0003713,"MLL3/4 complex; Set1C/COMPASS complex; cell cycle; chromatin binding; chromatin remodeling; histone H3 acetylation; histone H3-K4 methylation; histone H4 acetylation; histone acetyltransferase complex; positive regulation of growth; positive regulation of transcription, DNA-dependent; transcription coactivator activity",PF01344;,,,,,,,,,HCF_DROME,Drosophila melanogaster (Fruit fly),"cell cycle [GO:0007049]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4 acetylation [GO:0043967]; positive regulation of growth [GO:0045927]; positive regulation of transcription, DNA-templated [GO:0045893]" comp140904_c2_seq3,957,48.1714,0.66715676,55,10,,1.00E-28,Q9QYP0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity,PF00431;PF12947;PF07645;PF00053;PF01437;,,,,,,,,,MEGF8_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp140906_c0_seq1,1700,40.5882,0.57311341,45,143,,,,,,,,,2.00E-14,CHOYP_contig_030821,,,,,,,,, comp140906_c0_seq2,3230,40.0929,0.57455537,1,34,,1.00E-96,Q0P4V4,"Protein kintoun (Dynein assembly factor 2, axonemal)","Protein kintoun (Dynein assembly factor 2, axonemal)",GO:0005737,cytoplasm,PF08190;,9.00E-36,CHOYP_BRAFLDRAFT_126826.1.1,,,,,,,KTU_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp140906_c0_seq3,2807,41.254,0.57051544,0,0,,1.00E-97,Q0P4V4,"Protein kintoun (Dynein assembly factor 2, axonemal)","Protein kintoun (Dynein assembly factor 2, axonemal)",GO:0005737,cytoplasm,PF08190;,8.00E-36,CHOYP_BRAFLDRAFT_126826.1.1,,,,,,,KTU_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp140906_c0_seq4,1277,43.148,0.54662138,0,0,,,,,,,,,2.00E-14,CHOYP_contig_030821,,,,,,,,, comp140907_c0_seq2,1485,40.6734,0.7415173,26,123,,7.00E-35,O00602,Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin),Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin),GO:0003823; GO:0005509; GO:0030246; GO:0005581; GO:0001867; GO:0005576; GO:0008228,"antigen binding; calcium ion binding; carbohydrate binding; collagen; complement activation, lectin pathway; extracellular region; opsonization",PF01391;PF00147;,,,,,,,,,FCN1_HUMAN,Homo sapiens (Human),"cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]" comp140909_c2_seq1,4530,41.4128,0.3450825,0,0,,2.00E-40,Q9W596,Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)],Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)],GO:0008088; GO:0007409; GO:0048749; GO:0005737; GO:0048813; GO:0016787; GO:0005874; GO:0005875; GO:0008017; GO:0000226; GO:0043524; GO:0060052; GO:0007528; GO:0008355; GO:0008582,axon cargo transport; axonogenesis; compound eye development; cytoplasm; dendrite morphogenesis; hydrolase activity; microtubule; microtubule associated complex; microtubule binding; microtubule cytoskeleton organization; negative regulation of neuron apoptotic process; neurofilament cytoskeleton organization; neuromuscular junction development; olfactory learning; regulation of synaptic growth at neuromuscular junction,PF06740;,,,,,,,,,FUTSC_DROME,Drosophila melanogaster (Fruit fly),axo-dendritic transport [GO:0008088]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; dendrite morphogenesis [GO:0048813]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; regulation of synaptic growth at neuromuscular junction [GO:0008582] comp140909_c2_seq2,3047,41.2537,0.39433794,16,21,,4.00E-41,Q9W596,Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)],Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)],GO:0008088; GO:0007409; GO:0048749; GO:0005737; GO:0048813; GO:0016787; GO:0005874; GO:0005875; GO:0008017; GO:0000226; GO:0043524; GO:0060052; GO:0007528; GO:0008355; GO:0008582,axon cargo transport; axonogenesis; compound eye development; cytoplasm; dendrite morphogenesis; hydrolase activity; microtubule; microtubule associated complex; microtubule binding; microtubule cytoskeleton organization; negative regulation of neuron apoptotic process; neurofilament cytoskeleton organization; neuromuscular junction development; olfactory learning; regulation of synaptic growth at neuromuscular junction,PF06740;,,,,,,,,,FUTSC_DROME,Drosophila melanogaster (Fruit fly),axo-dendritic transport [GO:0008088]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; dendrite morphogenesis [GO:0048813]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; regulation of synaptic growth at neuromuscular junction [GO:0008582] comp140909_c2_seq5,4458,41.3638,0.34102731,0,0,,2.00E-12,P14401,Electromotor neuron-associated protein 2 (Fragment),Electromotor neuron-associated protein 2 (Fragment),GO:0012505; GO:0016787; GO:0016020; GO:0005874; GO:0000226,endomembrane system; hydrolase activity; membrane; microtubule; microtubule cytoskeleton organization,,,,,,,,,,ENP2_TORCA,Tetronarce californica (Pacific electric ray) (Torpedo californica),microtubule cytoskeleton organization [GO:0000226] comp140909_c3_seq1,1199,43.7031,0.57790855,3,8,,2.00E-90,Q9W596,Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)],Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)],GO:0008088; GO:0007409; GO:0048749; GO:0005737; GO:0048813; GO:0016787; GO:0005874; GO:0005875; GO:0008017; GO:0000226; GO:0043524; GO:0060052; GO:0007528; GO:0008355; GO:0008582,axon cargo transport; axonogenesis; compound eye development; cytoplasm; dendrite morphogenesis; hydrolase activity; microtubule; microtubule associated complex; microtubule binding; microtubule cytoskeleton organization; negative regulation of neuron apoptotic process; neurofilament cytoskeleton organization; neuromuscular junction development; olfactory learning; regulation of synaptic growth at neuromuscular junction,PF06740;,,,,,,,,,FUTSC_DROME,Drosophila melanogaster (Fruit fly),axo-dendritic transport [GO:0008088]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; dendrite morphogenesis [GO:0048813]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; regulation of synaptic growth at neuromuscular junction [GO:0008582] comp140909_c3_seq2,1229,43.9382,0.57445093,4,26,,,,,,,,,9.00E-18,CHOYP_SRC.1.2,,,,,,,,, comp140910_c0_seq1,1290,40.155,0.64260865,16,25,,9.00E-58,Q8HXD5,E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220),E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220),GO:0005737; GO:0051865; GO:0004842; GO:0008270,cytoplasm; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF15926;,,,,,,,,,RN220_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567] comp140910_c0_seq4,1638,41.3309,0.62116187,0,0,,,,,,,,,2.00E-46,CHOYP_RNF220.1.1,,,,,,,,, comp140910_c0_seq6,1661,41.481,0.61019489,7,6,,,,,,,,,2.00E-46,CHOYP_RNF220.1.1,,,,,,,,, comp140912_c0_seq1,640,46.5625,0.29457793,21,126,,1.00E-73,Q8JFW1,Asparagine synthetase domain-containing protein 1,Asparagine synthetase domain-containing protein 1,GO:0006529; GO:0004066; GO:0006541,asparagine biosynthetic process; asparagine synthase (glutamine-hydrolyzing) activity; glutamine metabolic process,PF00733;PF13537;,1.00E-56,CHOYP_ASND1.1.1,,,,,,,ASND1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541] comp140913_c0_seq1,752,36.1702,0.36640419,32,95,,2.00E-24,Q28CH8,Protein YIPF6 (YIP1 family member 6),Protein YIPF6 (YIP1 family member 6),GO:0016021,integral to membrane,PF04893;,,,,,,,,,YIPF6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp140913_c2_seq1,764,43.4555,0.72498757,0,0,,3.00E-14,Q9P2F6,Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),GO:0005096; GO:0005829; GO:0005543; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; phospholipid binding; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00620;,,,,,,,,,RHG20_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp140913_c2_seq3,1126,43.1616,0.59457161,0,0,,,,,,,,,2.00E-56,CHOYP_PHUM_PHUM087190.1.1,,,,,,,,, comp140913_c2_seq4,1898,43.7302,0.63060682,0,0,,1.00E-18,Q9P2F6,Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),GO:0005096; GO:0005829; GO:0005543; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; phospholipid binding; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00620;,,,,,,,,,RHG20_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp140916_c1_seq1,3363,45.1977,0.46011666,142,471,,0,Q99570,Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein),Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein),GO:0005524; GO:0005829; GO:0045087; GO:0008286; GO:0005770; GO:0006661; GO:0004672; GO:0004674; GO:0044281; GO:0034162,ATP binding; cytosol; innate immune response; insulin receptor signaling pathway; late endosome; phosphatidylinositol biosynthetic process; protein kinase activity; protein serine/threonine kinase activity; small molecule metabolic process; toll-like receptor 9 signaling pathway,PF00069;PF00400;,,,,,,,,,PI3R4_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; pexophagy [GO:0030242]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; toll-like receptor 9 signaling pathway [GO:0034162] comp140916_c1_seq2,1500,44.6,0.41586398,6,6,,8.00E-169,Q99570,Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein),Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein),GO:0005524; GO:0005829; GO:0045087; GO:0008286; GO:0005770; GO:0006661; GO:0004672; GO:0004674; GO:0044281; GO:0034162,ATP binding; cytosol; innate immune response; insulin receptor signaling pathway; late endosome; phosphatidylinositol biosynthetic process; protein kinase activity; protein serine/threonine kinase activity; small molecule metabolic process; toll-like receptor 9 signaling pathway,PF00069;PF00400;,5.00E-162,CHOYP_PI3R4.1.1,,,,,,,PI3R4_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; pexophagy [GO:0030242]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; toll-like receptor 9 signaling pathway [GO:0034162] comp140918_c0_seq1,3244,38.1628,0.5705225,3797,16266,,0,Q5ZL72,"60 kDa heat shock protein, mitochondrial (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60)","60 kDa heat shock protein, mitochondrial (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60)",GO:0005524; GO:0002368; GO:0042100; GO:0002755; GO:0006919; GO:0009986; GO:0005905; GO:0030135; GO:0019907; GO:0005829; GO:0005769; GO:0005615; GO:0048291; GO:0046696; GO:0005759; GO:0043066; GO:0050870; GO:0002842; GO:0043065; GO:0032733; GO:0032735; GO:0032755; GO:0043032; GO:0042026; GO:0006986,ATP binding; B cell cytokine production; B cell proliferation; MyD88-dependent toll-like receptor signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; cell surface; coated pit; coated vesicle; cyclin-dependent protein kinase activating kinase holoenzyme complex; cytosol; early endosome; extracellular space; isotype switching to IgG isotypes; lipopolysaccharide receptor complex; mitochondrial matrix; negative regulation of apoptotic process; positive regulation of T cell activation; positive regulation of T cell mediated immune response to tumor cell; positive regulation of apoptotic process; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; positive regulation of interleukin-6 production; positive regulation of macrophage activation; protein refolding; response to unfolded protein,PF00118;,0,CHOYP_CH60.1.1,,,,,,,CH60_CHICK,Gallus gallus (Chicken),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell cytokine production [GO:0002368]; B cell proliferation [GO:0042100]; isotype switching to IgG isotypes [GO:0048291]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of apoptotic process [GO:0043066]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage activation [GO:0043032]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; response to cold [GO:0009409]; response to unfolded protein [GO:0006986]; T cell activation [GO:0042110] comp140922_c0_seq1,2172,44.4291,0.56013828,0,0,,0,Q07327,Protein ROP,Protein ROP,GO:0000149; GO:0005829; GO:0019898; GO:0015031; GO:0007317; GO:0009416; GO:0016082; GO:0043195; GO:0006904,SNARE binding; cytosol; extrinsic to membrane; protein transport; regulation of pole plasm oskar mRNA localization; response to light stimulus; synaptic vesicle priming; terminal bouton; vesicle docking involved in exocytosis,PF00995;,0,CHOYP_STXB1.1.1,,,,,,,ROP_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; mitotic cytokinesis [GO:0000281]; neurotransmitter secretion [GO:0007269]; ovarian follicle cell development [GO:0030707]; protein transport [GO:0015031]; regulation of pole plasm oskar mRNA localization [GO:0007317]; response to light stimulus [GO:0009416]; secretion by cell [GO:0032940]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] comp140922_c0_seq11,2184,44.4139,0.56666636,0,0,,0,Q07327,Protein ROP,Protein ROP,GO:0000149; GO:0005829; GO:0019898; GO:0015031; GO:0007317; GO:0009416; GO:0016082; GO:0043195; GO:0006904,SNARE binding; cytosol; extrinsic to membrane; protein transport; regulation of pole plasm oskar mRNA localization; response to light stimulus; synaptic vesicle priming; terminal bouton; vesicle docking involved in exocytosis,PF00995;,0,CHOYP_STXB1.1.1,,,,,,,ROP_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; mitotic cytokinesis [GO:0000281]; neurotransmitter secretion [GO:0007269]; ovarian follicle cell development [GO:0030707]; protein transport [GO:0015031]; regulation of pole plasm oskar mRNA localization [GO:0007317]; response to light stimulus [GO:0009416]; secretion by cell [GO:0032940]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] comp140922_c0_seq13,2229,44.5491,0.56087896,0,0,,0,P61765,Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1),Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1),GO:0005829; GO:0005886; GO:0045921; GO:0047485; GO:0043234; GO:0019904; GO:0050821; GO:0015031; GO:0010807; GO:0017075; GO:0006904,cytosol; plasma membrane; positive regulation of exocytosis; protein N-terminus binding; protein complex; protein domain specific binding; protein stabilization; protein transport; regulation of synaptic vesicle priming; syntaxin-1 binding; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,STXB1_RAT,Rattus norvegicus (Rat),"axon target recognition [GO:0007412]; long term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904]" comp140922_c0_seq18,2289,44.8231,0.59173138,0,0,,0,Q15833,Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B),Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B),GO:0016324; GO:0042582; GO:0044194; GO:0005829; GO:0070062; GO:0001909; GO:0043312; GO:0005886; GO:0015031; GO:0043304; GO:0042581; GO:0070820; GO:0006904,apical plasma membrane; azurophil granule; cytolytic granule; cytosol; extracellular vesicular exosome; leukocyte mediated cytotoxicity; neutrophil degranulation; plasma membrane; protein transport; regulation of mast cell degranulation; specific granule; tertiary granule; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,STXB2_HUMAN,Homo sapiens (Human),leukocyte mediated cytotoxicity [GO:0001909]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]; regulation of mast cell degranulation [GO:0043304]; vesicle docking involved in exocytosis [GO:0006904] comp140922_c0_seq19,2286,44.5757,0.59031872,0,0,,6.00E-72,Q9SZ77,Protein transport Sec1b (AtSec1b),Protein transport Sec1b (AtSec1b),GO:0005886; GO:0015031; GO:0006904,plasma membrane; protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SEC1B_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp140922_c0_seq2,956,45.7113,0.64185181,0,0,,9.00E-06,P20795,Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5),Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5),GO:0005524; GO:0033263; GO:0006896; GO:0030897; GO:0005829; GO:0006897; GO:0000329; GO:0034727; GO:0006623; GO:0035542; GO:0032889; GO:0042144; GO:0048278; GO:0006904; GO:0051469,"ATP binding; CORVET complex; Golgi to vacuole transport; HOPS complex; cytosol; endocytosis; fungal-type vacuole membrane; piecemeal microautophagy of nucleus; protein targeting to vacuole; regulation of SNARE complex assembly; regulation of vacuole fusion, non-autophagic; vacuole fusion, non-autophagic; vesicle docking; vesicle docking involved in exocytosis; vesicle fusion with vacuole",PF00995;,,,,,,,,,VPS33_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"endocytosis [GO:0006897]; Golgi to vacuole transport [GO:0006896]; piecemeal microautophagy of nucleus [GO:0034727]; protein targeting to vacuole [GO:0006623]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]; vacuole fusion, non-autophagic [GO:0042144]; vacuole organization [GO:0007033]; vesicle docking [GO:0048278]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion with vacuole [GO:0051469]" comp140922_c0_seq27,2196,44.6266,0.55822984,0,0,,0,P61765,Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1),Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1),GO:0005829; GO:0005886; GO:0045921; GO:0047485; GO:0043234; GO:0019904; GO:0050821; GO:0015031; GO:0010807; GO:0017075; GO:0006904,cytosol; plasma membrane; positive regulation of exocytosis; protein N-terminus binding; protein complex; protein domain specific binding; protein stabilization; protein transport; regulation of synaptic vesicle priming; syntaxin-1 binding; vesicle docking involved in exocytosis,PF00995;,0,CHOYP_STXB1.1.1,,,,,,,STXB1_RAT,Rattus norvegicus (Rat),"axon target recognition [GO:0007412]; long term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904]" comp140922_c0_seq28,2217,44.5647,0.55447512,0,0,,7.00E-74,Q9C5P7,Protein transport Sec1a (AtSec1a),Protein transport Sec1a (AtSec1a),GO:0015031; GO:0006904,protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SEC1A_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp140922_c0_seq29,2310,44.7619,0.58795282,0,0,,6.00E-73,Q9C5P7,Protein transport Sec1a (AtSec1a),Protein transport Sec1a (AtSec1a),GO:0015031; GO:0006904,protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SEC1A_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp140922_c0_seq3,2205,44.3537,0.56279052,0,0,,2.00E-72,Q9SZ77,Protein transport Sec1b (AtSec1b),Protein transport Sec1b (AtSec1b),GO:0005886; GO:0015031; GO:0006904,plasma membrane; protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SEC1B_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp140922_c0_seq30,2193,44.3684,0.55628815,0,0,,0,Q07327,Protein ROP,Protein ROP,GO:0000149; GO:0005829; GO:0019898; GO:0015031; GO:0007317; GO:0009416; GO:0016082; GO:0043195; GO:0006904,SNARE binding; cytosol; extrinsic to membrane; protein transport; regulation of pole plasm oskar mRNA localization; response to light stimulus; synaptic vesicle priming; terminal bouton; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,ROP_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; mitotic cytokinesis [GO:0000281]; neurotransmitter secretion [GO:0007269]; ovarian follicle cell development [GO:0030707]; protein transport [GO:0015031]; regulation of pole plasm oskar mRNA localization [GO:0007317]; response to light stimulus [GO:0009416]; secretion by cell [GO:0032940]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] comp140922_c0_seq31,904,44.9115,0.59439612,0,0,,1.00E-05,P20795,Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5),Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5),GO:0005524; GO:0033263; GO:0006896; GO:0030897; GO:0005829; GO:0006897; GO:0000329; GO:0034727; GO:0006623; GO:0035542; GO:0032889; GO:0042144; GO:0048278; GO:0006904; GO:0051469,"ATP binding; CORVET complex; Golgi to vacuole transport; HOPS complex; cytosol; endocytosis; fungal-type vacuole membrane; piecemeal microautophagy of nucleus; protein targeting to vacuole; regulation of SNARE complex assembly; regulation of vacuole fusion, non-autophagic; vacuole fusion, non-autophagic; vesicle docking; vesicle docking involved in exocytosis; vesicle fusion with vacuole",PF00995;,,,,,,,,,VPS33_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"endocytosis [GO:0006897]; Golgi to vacuole transport [GO:0006896]; piecemeal microautophagy of nucleus [GO:0034727]; protein targeting to vacuole [GO:0006623]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]; vacuole fusion, non-autophagic [GO:0042144]; vacuole organization [GO:0007033]; vesicle docking [GO:0048278]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion with vacuole [GO:0051469]" comp140922_c0_seq5,1334,43.1784,0.69250295,0,0,,,,,,,,,3.00E-177,CHOYP_STXB1.1.1,,,,,,,,, comp140922_c0_seq7,2208,44.6105,0.56465895,0,0,,0,Q62753,Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Munc18-2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B),Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Munc18-2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B),GO:0016324; GO:0005737; GO:0030027; GO:0043234; GO:0015031; GO:0043304; GO:0010447; GO:0016079; GO:0006904,apical plasma membrane; cytoplasm; lamellipodium; protein complex; protein transport; regulation of mast cell degranulation; response to acidity; synaptic vesicle exocytosis; vesicle docking involved in exocytosis,PF00995;,0,CHOYP_STXB1.1.1,,,,,,,STXB2_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; regulation of mast cell degranulation [GO:0043304]; response to acidic pH [GO:0010447]; synaptic vesicle exocytosis [GO:0016079]; vesicle docking involved in exocytosis [GO:0006904] comp140922_c0_seq8,2265,44.6358,0.59419212,0,0,,1.00E-16,O18637,Protein sly1 homolog,Protein sly1 homolog,GO:0005737; GO:0016020; GO:0006904,cytoplasm; membrane; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SLY1_DROVI,Drosophila virilis (Fruit fly),vesicle docking involved in exocytosis [GO:0006904] comp140923_c0_seq1,2777,34.4977,0.82594715,1,26,,1.00E-08,Q08731,Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP),Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP),GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,LIT2_MOUSE,Mus musculus (Mouse),myelination [GO:0042552]; suckling behavior [GO:0001967] comp140923_c0_seq3,2850,34.2105,0.83078824,2,28,,3.00E-06,Q90WJ8,Lactose-binding lectin l-2 (Ajl-2),Lactose-binding lectin l-2 (Ajl-2),GO:0030246; GO:0050829; GO:0005576; GO:0043152,carbohydrate binding; defense response to Gram-negative bacterium; extracellular region; induction of bacterial agglutination,PF00059;,,,,,,,,,AJL2_ANGJA,Anguilla japonica (Japanese eel),defense response to Gram-negative bacterium [GO:0050829]; induction of bacterial agglutination [GO:0043152] comp140923_c0_seq4,2615,34.761,0.81285636,5,55,,9.00E-09,Q08731,Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP),Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP),GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,LIT2_MOUSE,Mus musculus (Mouse),myelination [GO:0042552]; suckling behavior [GO:0001967] comp140924_c2_seq10,1877,36.4411,0.47055889,0,0,,5.00E-07,Q7PSY2,UPF0729 protein AGAP000931,UPF0729 protein AGAP000931,,,PF14975;,5.00E-11,CHOYP_LOC100373008.1.1,,,,,,,U729_ANOGA,Anopheles gambiae (African malaria mosquito), comp140924_c2_seq2,1890,36.3492,0.46978562,0,0,,,,,,,,,,,5.00E-21,ruditapes_c14363,,,,,,, comp140924_c2_seq3,2127,37.3296,0.43671448,133,248,,,,,,,,,5.00E-11,CHOYP_LOC100373008.1.1,,,,,,,,, comp140927_c1_seq2,2419,39.6858,0.34091865,69,121,,2.00E-104,Q5R806,Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase),Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase),GO:0036132; GO:0047522; GO:0005737; GO:0006693,13-prostaglandin reductase activity; 15-oxoprostaglandin 13-oxidase activity; cytoplasm; prostaglandin metabolic process,PF00107;,,,,,,,,,PTGR2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),prostaglandin metabolic process [GO:0006693] comp140927_c1_seq3,675,42.0741,0.24044768,0,0,,3.00E-19,Q8BGC4,Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-),Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-),GO:0005739; GO:0016491; GO:0005777; GO:0008270,mitochondrion; oxidoreductase activity; peroxisome; zinc ion binding,PF08240;PF00107;,4.00E-26,CHOYP_BRAFLDRAFT_276226.2.2,,,,,,,ZADH2_MOUSE,Mus musculus (Mouse), comp140927_c1_seq4,2660,38.3083,0.38112884,20,329,,6.00E-52,O34812,Putative NADP-dependent oxidoreductase YfmJ (EC 1.-.-.-),Putative NADP-dependent oxidoreductase YfmJ (EC 1.-.-.-),GO:0019439; GO:0016491; GO:0009636; GO:0008270,aromatic compound catabolic process; oxidoreductase activity; response to toxic substance; zinc ion binding,PF00107;,,,,,,,,,YFMJ_BACSU,Bacillus subtilis (strain 168),aromatic compound catabolic process [GO:0019439]; response to toxic substance [GO:0009636] comp140928_c0_seq2,1805,37.3407,1.10991991,43,239,,4.00E-12,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp140929_c0_seq2,2477,42.9148,0.38659723,7,38,,0,Q9UGJ1,Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76),Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76),GO:0000086; GO:0005813; GO:0005829; GO:0008274; GO:0005874; GO:0007020; GO:0006461; GO:0000922; GO:0005200,G2/M transition of mitotic cell cycle; centrosome; cytosol; gamma-tubulin ring complex; microtubule; microtubule nucleation; protein complex assembly; spindle pole; structural constituent of cytoskeleton,PF04130;,,,,,,,,,GCP4_HUMAN,Homo sapiens (Human),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; protein complex assembly [GO:0006461] comp140929_c0_seq3,2543,43.0594,0.40818843,7,28,,2.00E-72,Q9SC88,Gamma-tubulin complex component 4 homolog,Gamma-tubulin complex component 4 homolog,GO:0005737; GO:0005874; GO:0000226; GO:0005815; GO:0000922,cytoplasm; microtubule; microtubule cytoskeleton organization; microtubule organizing center; spindle pole,PF04130;,,,,,,,,,GCP4_MEDTR,Medicago truncatula (Barrel medic) (Medicago tribuloides),cortical microtubule organization [GO:0043622]; growth [GO:0040007]; microtubule nucleation [GO:0007020]; response to nematode [GO:0009624] comp140929_c0_seq5,2393,43.7108,0.38591266,16,174,,4.00E-23,O73787,Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p),Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p),GO:0005737; GO:0005874; GO:0007020; GO:0005815; GO:0000922,cytoplasm; microtubule; microtubule nucleation; microtubule organizing center; spindle pole,PF04130;,4.00E-70,CHOYP_GCP4.1.1,3.00E-18,ruditapes_c8377,,,,,GCP3_XENLA,Xenopus laevis (African clawed frog),microtubule nucleation [GO:0007020] comp140930_c0_seq1,1844,46.7462,0.74558731,5369,61886,,0,Q68FR8,Tubulin alpha-3 chain (Alpha-tubulin 3),Tubulin alpha-3 chain (Alpha-tubulin 3),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC584364.1.2,0,ruditapes2_lrc3145,,,,,TBA3_RAT,Rattus norvegicus (Rat),microtubule-based process [GO:0007017] comp140930_c0_seq2,1811,46.8802,0.78464227,6257,64077,,0,P53371,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC584364.1.2,0,ruditapes2_c97,,,,,TBA_AJECA,Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum),microtubule-based process [GO:0007017] comp140930_c0_seq3,1440,49.5833,0.81470644,1994,35116,,0,Q68FR8,Tubulin alpha-3 chain (Alpha-tubulin 3),Tubulin alpha-3 chain (Alpha-tubulin 3),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,0,CHOYP_LOC100366892.2.3,0,ruditapes_c12803,,,,,TBA3_RAT,Rattus norvegicus (Rat),microtubule-based process [GO:0007017] comp140930_c0_seq4,700,53.7143,0.74278297,7129,45653,,2.00E-78,P86234,Tubulin alpha-3 chain (Fragments),Tubulin alpha-3 chain (Fragments),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization,PF00091;PF03953;,2.00E-169,CHOYP_BRAFLDRAFT_58035.1.2,,,,,,,TBA3_MESAU,Mesocricetus auratus (Golden hamster),microtubule-based process [GO:0007017] comp140930_c0_seq5,1120,48.4821,0.85247216,1414,4408,,7.00E-158,P24635,Tubulin alpha chain (Fragment),Tubulin alpha chain (Fragment),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF03953;,0,CHOYP_TBA.3.6,7.00E-93,ruditapes_lrc38746,,,,,TBA_OCTVU,Octopus vulgaris (Common octopus),microtubule-based process [GO:0007017] comp140932_c0_seq1,1472,44.4293,0.58380083,0,0,,3.00E-121,Q5ZKA3,Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog),Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog),GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0005681,RNA binding; RNA splicing; mRNA processing; nuclear speck; spliceosomal complex,PF02847;,,,,,,,,,CWC22_CHICK,Gallus gallus (Chicken),"mRNA splicing, via spliceosome [GO:0000398]" comp140932_c0_seq13,910,42.967,0.48254733,0,0,,4.00E-109,Q9HCG8,Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb),Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb),GO:0003723; GO:0071013; GO:0005737; GO:0000398; GO:0016607; GO:0048024,"RNA binding; catalytic step 2 spliceosome; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; regulation of mRNA splicing, via spliceosome",PF02847;,,,,,,,,,CWC22_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA splicing, via spliceosome [GO:0048024]" comp140932_c0_seq4,1472,44.4293,0.55347689,0,0,,7.00E-119,Q08C72,Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog),Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog),GO:0003723; GO:0008380; GO:0006397; GO:0005681,RNA binding; RNA splicing; mRNA processing; spliceosomal complex,PF02847;PF02854;,,,,,,,,,CWC22_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA splicing, via spliceosome [GO:0000398]" comp140932_c0_seq5,1905,44.4619,0.56157305,0,0,,0,Q5ZKA3,Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog),Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog),GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0005681,RNA binding; RNA splicing; mRNA processing; nuclear speck; spliceosomal complex,PF02847;,0,CHOYP_CWC22.1.1,,,,,,,CWC22_CHICK,Gallus gallus (Chicken),"mRNA splicing, via spliceosome [GO:0000398]" comp140932_c0_seq6,604,42.8808,0.47209013,0,0,,5.00E-23,P53333,Pre-mRNA-splicing factor CWC22 (Complexed with CEF1 protein 22),Pre-mRNA-splicing factor CWC22 (Complexed with CEF1 protein 22),GO:0003723; GO:0005684; GO:0005737; GO:0000398,"RNA binding; U2-type spliceosomal complex; cytoplasm; mRNA splicing, via spliceosome",PF02847;,,,,,,,,,CWC22_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"mRNA splicing, via spliceosome [GO:0000398]" comp140932_c0_seq9,1343,44.6761,0.60986296,0,9,,,,,,,,,1.00E-149,CHOYP_CWC22.1.1,,,,,,,,, comp140935_c0_seq1,2274,38.8303,0.31116518,5,31,,2.00E-116,Q29551,"Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)","Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)",GO:0008260; GO:0046950; GO:0046952; GO:0042182; GO:0005739; GO:0042803,3-oxoacid CoA-transferase activity; cellular ketone body metabolic process; ketone body catabolic process; ketone catabolic process; mitochondrion; protein homodimerization activity,PF01144;,2.00E-174,CHOYP_SCOT1.1.1,,,,,,,SCOT1_PIG,Sus scrofa (Pig),cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952] comp140935_c0_seq2,2298,38.9469,0.34165033,3,39,,2.00E-116,Q29551,"Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)","Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)",GO:0008260; GO:0046950; GO:0046952; GO:0042182; GO:0005739; GO:0042803,3-oxoacid CoA-transferase activity; cellular ketone body metabolic process; ketone body catabolic process; ketone catabolic process; mitochondrion; protein homodimerization activity,PF01144;,6.00E-163,CHOYP_SCOT1.1.1,,,,,,,SCOT1_PIG,Sus scrofa (Pig),cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952] comp140936_c0_seq2,1096,43.1569,0.80475437,13,23,,5.00E-14,Q5RJY4,Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 32C member 1),GO:0016021; GO:0016491; GO:0005778,integral to membrane; oxidoreductase activity; peroxisomal membrane,PF00106;,,,,,,,,,DRS7B_RAT,Rattus norvegicus (Rat), comp140936_c0_seq3,1184,44.3412,0.86535084,21,116,,4.00E-56,P29147,"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase)","D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH)",GO:0003858; GO:0060612; GO:0007420; GO:0001889; GO:0005743; GO:0005759; GO:0005543; GO:0046686; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0060416; GO:0032868; GO:0007584; GO:0042594; GO:0009636,3-hydroxybutyrate dehydrogenase activity; adipose tissue development; brain development; liver development; mitochondrial inner membrane; mitochondrial matrix; phospholipid binding; response to cadmium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to growth hormone stimulus; response to insulin stimulus; response to nutrient; response to starvation; response to toxic substance,PF00106;,,,,,,,,,BDH_RAT,Rattus norvegicus (Rat),adipose tissue development [GO:0060612]; brain development [GO:0007420]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636] comp140937_c0_seq11,1256,35.4299,0.55866702,332,1526,,7.00E-124,Q8AVH4,RNA-binding protein PNO1,RNA-binding protein PNO1,GO:0003723; GO:0005730,RNA binding; nucleolus,PF00013;,3.00E-107,CHOYP_PNO1.3.3,2.00E-139,ruditapes_c8855,,,,,PNO1_XENLA,Xenopus laevis (African clawed frog), comp140938_c0_seq1,525,46.8571,0.83531038,302,587,,4.00E-60,Q5RDT5,Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p18),Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p18),GO:0061574; GO:0005737; GO:0048025; GO:0016607; GO:0005886; GO:0043065; GO:0000381; GO:0006355; GO:0006351,"ASAP complex; cytoplasm; negative regulation of mRNA splicing, via spliceosome; nuclear speck; plasma membrane; positive regulation of apoptotic process; regulation of alternative mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF06487;,3.00E-38,CHOYP_LOC100313731.1.1,4.00E-85,ruditapes_c341,,,,,SAP18_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp140938_c2_seq1,1622,38.9026,0.77672928,31,2860,,5.00E-35,Q24799,Myophilin,Myophilin,,,PF00402;PF00307;,,,,,,,,,MYPH_ECHGR,Echinococcus granulosus (Hydatid tapeworm), comp140939_c0_seq1,4329,38.8542,0.594948,1147,3799,,2.00E-50,Q5ZIQ3,Heterogeneous nuclear ribonucleoprotein K (hnRNP K),Heterogeneous nuclear ribonucleoprotein K (hnRNP K),GO:0003677; GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0005654; GO:0006355; GO:0005681; GO:0006351,"DNA binding; RNA binding; RNA splicing; cytoplasm; mRNA processing; nucleoplasm; regulation of transcription, DNA-dependent; spliceosomal complex; transcription, DNA-dependent",PF00013;PF08067;,8.00E-44,CHOYP_Y023.1.1,,,,,,,HNRPK_CHICK,Gallus gallus (Chicken),"mRNA processing [GO:0006397]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp140939_c0_seq2,4359,38.9539,0.59441039,1909,4263,,1.00E-46,Q3T0D0,Heterogeneous nuclear ribonucleoprotein K (hnRNP K),Heterogeneous nuclear ribonucleoprotein K (hnRNP K),GO:0003677; GO:0003723; GO:0008380; GO:0030054; GO:0042995; GO:0005737; GO:0006397; GO:0005654; GO:0002102; GO:0006355; GO:0005681; GO:0006351,"DNA binding; RNA binding; RNA splicing; cell junction; cell projection; cytoplasm; mRNA processing; nucleoplasm; podosome; regulation of transcription, DNA-dependent; spliceosomal complex; transcription, DNA-dependent",PF00013;PF08067;,2.00E-25,CHOYP_BRAFLDRAFT_115392.1.1,,,,,,,HNRPK_BOVIN,Bos taurus (Bovine),"mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA splicing [GO:0008380]" comp140941_c2_seq11,1413,41.3305,0.50395036,0,7,,4.00E-08,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp140941_c2_seq17,1566,41.507,0.52341028,0,0,,3.00E-08,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp140941_c2_seq23,1410,41.2766,0.50489052,0,0,,4.00E-08,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp140941_c2_seq26,1670,40.8982,0.51894429,0,0,,1.00E-06,Q8TB03,Uncharacterized protein CXorf38,Uncharacterized protein CXorf38,,,PF15112;,,,,,,,,,CX038_HUMAN,Homo sapiens (Human), comp140941_c2_seq27,2642,39.894,0.51317012,0,0,,2.00E-07,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp140941_c2_seq3,1428,41.3866,0.54888636,0,0,,5.00E-08,Q8C5K5,Uncharacterized protein CXorf38 homolog,Uncharacterized protein CXorf38 homolog,,,PF15112;,,,,,,,,,CX038_MOUSE,Mus musculus (Mouse), comp140941_c2_seq6,1608,41.107,0.50337714,0,0,,9.00E-07,Q8TB03,Uncharacterized protein CXorf38,Uncharacterized protein CXorf38,,,PF15112;,,,,,,,,,CX038_HUMAN,Homo sapiens (Human), comp140942_c0_seq1,2665,42.5141,0.44682042,1086,2571,,0,Q5R6Y0,HBS1-like protein,HBS1-like protein,GO:0005525; GO:0006184; GO:0003924; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; translation elongation factor activity,PF03144;PF03143;PF08938;,7.00E-163,CHOYP_HBS1L.1.2,,,,,,,HBS1L_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp140945_c0_seq2,1098,36.7942,1.10647637,27,75,,9.00E-15,Q8L5A7,Cytosolic sulfotransferase 15 (AtSOT15) (EC 2.8.2.-) (Sulfotransferase 2a) (AtST2a),Cytosolic sulfotransferase 15 (AtSOT15) (EC 2.8.2.-) (Sulfotransferase 2a) (AtST2a),GO:0005737; GO:0080131; GO:0009694; GO:0009753,cytoplasm; hydroxyjasmonate sulfotransferase activity; jasmonic acid metabolic process; response to jasmonic acid stimulus,PF00685;,,,,,,,,,SOT15_ARATH,Arabidopsis thaliana (Mouse-ear cress),jasmonic acid metabolic process [GO:0009694]; response to jasmonic acid [GO:0009753] comp140945_c0_seq3,1062,36.4407,1.05247618,11,0,,8.00E-33,O46640,Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1),Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1),GO:0047685; GO:0005737,amine sulfotransferase activity; cytoplasm,PF00685;,,,,,,,,,ST3A1_RABIT,Oryctolagus cuniculus (Rabbit), comp140945_c0_seq5,425,42.5882,0.89407902,7,18,,2.00E-06,Q9BR01,Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST),Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST),GO:0050427; GO:0005829; GO:0008202; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; steroid metabolic process; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST4A1_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; steroid metabolic process [GO:0008202] comp140948_c0_seq1,3655,41.7237,0.60630187,4799,30011,,0,Q6PFQ2,Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8),Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity; translational initiation,PF05470;PF01399;,0,CHOYP_EIF3C.1.1,,,,,,,EIF3C_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp140952_c0_seq1,1830,39.2896,0.41587575,8,1,,5.00E-121,Q5ZKL6,Membrane-bound O-acyltransferase domain-containing protein 2 (O-acyltransferase domain-containing protein 2) (EC 2.3.-.-),Membrane-bound O-acyltransferase domain-containing protein 2 (O-acyltransferase domain-containing protein 2) (EC 2.3.-.-),GO:0016021; GO:0008654; GO:0016746,"integral to membrane; phospholipid biosynthetic process; transferase activity, transferring acyl groups",PF03062;,,,,,,,,,MBOA2_CHICK,Gallus gallus (Chicken),phospholipid biosynthetic process [GO:0008654] comp140952_c0_seq2,1347,42.6132,0.42988935,3,0,,,,,,,,,5.00E-28,CHOYP_MBOA2.1.1,,,,,,,,, comp140952_c0_seq4,689,41.9448,0.4741347,3,0,,5.00E-08,B1Q005,Ghrelin O-acyltransferase (EC 2.3.1.-) (Membrane-bound O-acyltransferase domain-containing protein 4),Ghrelin O-acyltransferase (EC 2.3.1.-) (Membrane-bound O-acyltransferase domain-containing protein 4),GO:0030176; GO:0018191; GO:0016412,integral to endoplasmic reticulum membrane; peptidyl-serine octanoylation; serine O-acyltransferase activity,PF03062;,,,,,,,,,MBOA4_RAT,Rattus norvegicus (Rat),peptidyl-serine octanoylation [GO:0018191] comp140952_c0_seq6,1675,38.8657,0.43451391,0,0,,3.00E-58,Q08548,Lysophospholipid acyltransferase (LPLAT) (EC 2.3.1.23) (EC 2.3.1.51) (1-acyl-sn-glycerol-3-phosphate acyltransferase) (AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lysophosphatidylethanolamine acyltransferase) (LPEAT),Lysophospholipid acyltransferase (LPLAT) (EC 2.3.1.23) (EC 2.3.1.51) (1-acyl-sn-glycerol-3-phosphate acyltransferase) (AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lysophosphatidylethanolamine acyltransferase) (LPEAT),GO:0003841; GO:0047184; GO:0005783; GO:0005789; GO:0046474; GO:0016021,1-acylglycerol-3-phosphate O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; glycerophospholipid biosynthetic process; integral to membrane,PF03062;,5.00E-29,CHOYP_MBOA2.1.1,,,,,,,ALE1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),glycerophospholipid biosynthetic process [GO:0046474] comp140953_c0_seq1,2014,37.289,0.94574053,202,1585,,1.00E-38,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,,,,,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp140956_c1_seq1,2520,35.3571,0.5989638,52,0,,2.00E-105,Q86UC2,Radial spoke head protein 3 homolog (Radial spoke head-like protein 2),Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2),,,PF06098;,,,,,,,,,RSPH3_HUMAN,Homo sapiens (Human), comp140956_c1_seq2,1833,38.2433,0.62875913,0,0,,,,,,,,,0,CHOYP_LOC100378839.1.1,,,,,,,,, comp140956_c1_seq6,1832,38.9738,0.66387964,137,2,,4.00E-108,Q86UC2,Radial spoke head protein 3 homolog (Radial spoke head-like protein 2),Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2),,,PF06098;,0,CHOYP_LOC100378839.1.1,1.00E-61,ruditapes_c25101,2.00E-97,AM860858.p.cg.6,5,,RSPH3_HUMAN,Homo sapiens (Human), comp140959_c2_seq1,434,40.553,0.45526144,13,17,,,,,,,,,7.00E-33,CHOYP_LOC100123810.2.2,,,,,,,,, comp140959_c3_seq1,1351,43.0792,0.319452,35,221,,3.00E-94,Q12767,Uncharacterized protein KIAA0195 (Transmembrane protein 94),Transmembrane protein 94,GO:0016021,integral to membrane,PF00689;,3.00E-25,CHOYP_LOC100123810.2.2,,,,,,,K0195_HUMAN,Homo sapiens (Human), comp140959_c4_seq1,526,41.4449,0.4145994,10,51,,,,,,,,,3.00E-25,CHOYP_LOC100123810.1.2,,,,,,,,, comp140961_c1_seq1,2037,44.8699,0.49406073,167,421,,2.00E-133,Q8IZ83,Aldehyde dehydrogenase family 16 member A1,Aldehyde dehydrogenase family 16 member A1,GO:0016620,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",PF00171;,0,CHOYP_BRAFLDRAFT_287353.1.1,,,,,,,A16A1_HUMAN,Homo sapiens (Human), comp140962_c1_seq1,2577,41.3659,0.56913554,0,0,,0,Q13330,Metastasis-associated protein MTA1,Metastasis-associated protein MTA1,GO:0016581; GO:0003682; GO:0005737; GO:0005783; GO:0005634; GO:0033363; GO:0043565; GO:0003700; GO:0007165; GO:0008270,NuRD complex; chromatin binding; cytoplasm; endoplasmic reticulum; nucleus; secretory granule organization; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transduction; zinc ion binding,PF01426;PF01448;PF00320;PF00249;,0,CHOYP_MTA1.1.1,,,,,,,MTA1_HUMAN,Homo sapiens (Human),"circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp140962_c1_seq3,2824,40.9703,0.5897847,0,0,,7.00E-40,Q80TZ9,Arginine-glutamic acid dipeptide repeats protein (Atrophin-2),Arginine-glutamic acid dipeptide repeats protein (Atrophin-2),GO:0016605; GO:0003682; GO:0006338; GO:0000118; GO:0005739; GO:0007275; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"PML body; chromatin binding; chromatin remodeling; histone deacetylase complex; mitochondrion; multicellular organismal development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF03154;PF01426;PF01448;PF00320;,,,,,,,,,RERE_MOUSE,Mus musculus (Mouse),branching morphogenesis of a nerve [GO:0048755]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell layer maturation [GO:0021691]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; dendrite morphogenesis [GO:0048813]; radial glia guided migration of Purkinje cell [GO:0021942] comp140962_c1_seq4,2613,41.4083,0.56898347,0,0,,5.00E-10,Q7T105,Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (Xmi-er1),Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (Xmi-er1),GO:0003677; GO:0003682; GO:0031937; GO:0006351; GO:0017053,"DNA binding; chromatin binding; positive regulation of chromatin silencing; transcription, DNA-dependent; transcriptional repressor complex",PF01448;PF00249;,,,,,,,,,MIER1_XENLA,Xenopus laevis (African clawed frog),"positive regulation of chromatin silencing [GO:0031937]; transcription, DNA-templated [GO:0006351]" comp140962_c1_seq5,3041,40.8418,0.59213243,0,0,,1.00E-31,Q09228,Egg-laying defective protein 27,Egg-laying defective protein 27,GO:0016581; GO:0016055; GO:0010171; GO:0007155; GO:0001708; GO:0003682; GO:0009792; GO:0008544; GO:0007163; GO:0031581; GO:0007498; GO:0002119; GO:0018991; GO:0009786; GO:0030334; GO:0006357; GO:0043565; GO:0003700; GO:0045138; GO:0006351; GO:0060290; GO:0008270,"NuRD complex; Wnt receptor signaling pathway; body morphogenesis; cell adhesion; cell fate specification; chromatin binding; embryo development ending in birth or egg hatching; epidermis development; establishment or maintenance of cell polarity; hemidesmosome assembly; mesoderm development; nematode larval development; oviposition; regulation of asymmetric cell division; regulation of cell migration; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tail tip morphogenesis; transcription, DNA-dependent; transdifferentiation; zinc ion binding",PF01426;PF01448;,0,CHOYP_MTA1.1.1,,,,,,,EGL27_CAEEL,Caenorhabditis elegans,"body morphogenesis [GO:0010171]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; embryo development ending in birth or egg hatching [GO:0009792]; epidermis development [GO:0008544]; establishment or maintenance of cell polarity [GO:0007163]; hemidesmosome assembly [GO:0031581]; mesoderm development [GO:0007498]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; regulation of asymmetric cell division [GO:0009786]; regulation of cell migration [GO:0030334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; transdifferentiation [GO:0060290]; Wnt signaling pathway [GO:0016055]" comp140962_c1_seq7,3005,40.7987,0.59260646,0,0,,0,Q8K4B0,Metastasis-associated protein MTA1,Metastasis-associated protein MTA1,GO:0016581; GO:0003682; GO:0005737; GO:0043565; GO:0003700; GO:0008270,NuRD complex; chromatin binding; cytoplasm; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF01426;PF01448;PF00320;PF00249;,,,,,,,,,MTA1_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]" comp140962_c1_seq8,2788,40.9254,0.59024626,0,0,,0,Q8K4B0,Metastasis-associated protein MTA1,Metastasis-associated protein MTA1,GO:0016581; GO:0003682; GO:0005737; GO:0043565; GO:0003700; GO:0008270,NuRD complex; chromatin binding; cytoplasm; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF01426;PF01448;PF00320;PF00249;,0,CHOYP_MTA1.1.1,,,,,,,MTA1_MOUSE,Mus musculus (Mouse),"circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]" comp140963_c1_seq2,1639,46.4918,0.28471244,2,12,,,,,,,,,2.00E-72,CHOYP_CREBBP.1.1,,,,,,,,, comp140963_c1_seq3,1825,47.1233,0.3288852,62,40,,,,,,,,,9.00E-58,CHOYP_LOC100366719.1.1,,,,,,,,, comp140963_c2_seq1,5274,44.3876,0.51254376,7,21,,0,Q6JHU9,CREB-binding protein (EC 2.3.1.48),CREB-binding protein (EC 2.3.1.48),GO:0043426; GO:0008283; GO:0005737; GO:0004402; GO:0000123; GO:0005634; GO:0042975; GO:0045944; GO:0003713; GO:0005667; GO:0006351; GO:0008270,"MRF binding; cell proliferation; cytoplasm; histone acetyltransferase activity; histone acetyltransferase complex; nucleus; peroxisome proliferator activated receptor binding; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent; zinc ion binding",PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;,,,,,,,,,CBP_RAT,Rattus norvegicus (Rat),"cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular response to UV [GO:0034644]; histone acetylation [GO:0016573]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp140963_c2_seq2,4207,43.9981,0.54048377,0,0,,1.00E-159,Q92793,CREB-binding protein (EC 2.3.1.48),CREB-binding protein (EC 2.3.1.48),GO:0043426; GO:0018076; GO:0007219; GO:0001102; GO:0001078; GO:0001105; GO:0001191; GO:0044255; GO:0003682; GO:0000940; GO:0000987; GO:0005737; GO:0042733; GO:0030718; GO:0004402; GO:0000123; GO:0042592; GO:0045087; GO:0019048; GO:0016604; GO:0000790; GO:0032481; GO:0006461; GO:0008589; GO:0061418; GO:0004871; GO:0044281; GO:0005667; GO:0006367; GO:0008270,MRF binding; N-terminal peptidyl-lysine acetylation; Notch signaling pathway; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II transcription coactivator activity; RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; cellular lipid metabolic process; chromatin binding; condensed chromosome outer kinetochore; core promoter proximal region sequence-specific DNA binding; cytoplasm; embryonic digit morphogenesis; germ-line stem cell maintenance; histone acetyltransferase activity; histone acetyltransferase complex; homeostatic process; innate immune response; modulation by virus of host morphology or physiology; nuclear body; nuclear chromatin; positive regulation of type I interferon production; protein complex assembly; regulation of smoothened signaling pathway; regulation of transcription from RNA polymerase II promoter in response to hypoxia; signal transducer activity; small molecule metabolic process; transcription factor complex; transcription initiation from RNA polymerase II promoter; zinc ion binding,PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;,0,CHOYP_LOC664565.1.1,1.00E-96,ruditapes_c20089,5.00E-114,AM857825.p.cg.6,3,,CBP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular lipid metabolic process [GO:0044255]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein complex assembly [GO:0006461]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp140963_c2_seq3,1787,43.3128,0.46560027,2,27,,2.00E-172,Q6JHU9,CREB-binding protein (EC 2.3.1.48),CREB-binding protein (EC 2.3.1.48),GO:0043426; GO:0008283; GO:0005737; GO:0004402; GO:0000123; GO:0005634; GO:0042975; GO:0045944; GO:0003713; GO:0005667; GO:0006351; GO:0008270,"MRF binding; cell proliferation; cytoplasm; histone acetyltransferase activity; histone acetyltransferase complex; nucleus; peroxisome proliferator activated receptor binding; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent; zinc ion binding",PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;,3.00E-127,CHOYP_CBP.2.4,,,,,,,CBP_RAT,Rattus norvegicus (Rat),"cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular response to UV [GO:0034644]; histone acetylation [GO:0016573]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp140963_c2_seq4,729,39.6433,0.57736144,0,0,,,,,,,,,6.00E-24,CHOYP_EP300.1.1,,,,,,,,, comp140964_c0_seq1,1647,42.1979,0.43373592,7,59,,2.00E-55,Q0P5B1,Peroxisomal membrane protein PEX13 (Peroxin-13),Peroxisomal membrane protein PEX13 (Peroxin-13),GO:0021795; GO:0001561; GO:0005779; GO:0007626; GO:0060152; GO:0001764; GO:0016560; GO:0001967,"cerebral cortex cell migration; fatty acid alpha-oxidation; integral to peroxisomal membrane; locomotory behavior; microtubule-based peroxisome localization; neuron migration; protein import into peroxisome matrix, docking; suckling behavior",PF04088;PF14604;,,,,,,,,,PEX13_BOVIN,Bos taurus (Bovine),"cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; mitophagy in response to mitochondrial depolarization [GO:0098779]; neuron migration [GO:0001764]; positive regulation of defense response to virus by host [GO:0002230]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967]; xenophagy [GO:0098792]" comp140964_c0_seq2,1629,42.2345,0.44040248,3,54,,1.00E-55,Q92968,Peroxisomal membrane protein PEX13 (Peroxin-13),Peroxisomal membrane protein PEX13 (Peroxin-13),GO:0021795; GO:0001561; GO:0005779; GO:0007626; GO:0060152; GO:0001764; GO:0016560; GO:0001967,"cerebral cortex cell migration; fatty acid alpha-oxidation; integral to peroxisomal membrane; locomotory behavior; microtubule-based peroxisome localization; neuron migration; protein import into peroxisome matrix, docking; suckling behavior",PF04088;PF14604;,8.00E-39,CHOYP_LOC594428.1.1,,,,,,,PEX13_HUMAN,Homo sapiens (Human),"cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; mitophagy in response to mitochondrial depolarization [GO:0098779]; neuron migration [GO:0001764]; positive regulation of defense response to virus by host [GO:0002230]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967]; xenophagy [GO:0098792]" comp140968_c2_seq2,836,34.2105,0.4132727,38,483,,,,,,,,,6.00E-12,CHOYP_contig_028975,,,,,,,,, comp140969_c1_seq1,2426,37.6752,0.90960039,4,943,female>male,2.00E-20,Q08BN9,NXPE family member 3 (Protein FAM55C),NXPE family member 3 (Protein FAM55C),GO:0005576,extracellular region,PF06312;,,,,,,,,,NXPE3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140974_c4_seq1,1082,33.549,0.72525327,67,52,,5.00E-13,Q03278,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO21_NASVI,Nasonia vitripennis (Parasitic wasp), comp140976_c0_seq1,1244,44.373,1.22579666,0,0,,1.00E-35,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp140976_c0_seq5,1632,43.1985,1.27510392,0,0,,4.00E-36,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp140977_c1_seq1,288,42.7083,0.23269202,2,3,,8.00E-16,Q5XGG3,PIH1 domain-containing protein 2,PIH1 domain-containing protein 2,,,PF08190;,,,,,,,,,PIHD2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp140977_c1_seq3,925,37.8378,0.39463723,67,90,,6.00E-33,Q5PRB3,PIH1 domain-containing protein 2,PIH1 domain-containing protein 2,,,PF08190;,,,,,,,,,PIHD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp140977_c2_seq1,1269,38.6131,0.5082036,9,57,,3.00E-06,Q6CR04,UDP-galactose transporter homolog 1,UDP-galactose transporter homolog 1,GO:0008643; GO:0005789; GO:0016021; GO:0055085,carbohydrate transport; endoplasmic reticulum membrane; integral to membrane; transmembrane transport,PF08449;,,,,,,,,,HUT1_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),UDP-glucose transport [GO:0015786] comp140977_c2_seq2,1268,38.8013,0.50348017,17,107,,1.00E-122,Q95KB4,UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4),UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4),GO:0000139; GO:0008643; GO:0016021; GO:0055085,Golgi membrane; carbohydrate transport; integral to membrane; transmembrane transport,PF08449;,,,,,,,,,S35B4_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085] comp140978_c0_seq1,1959,43.4405,0.65587261,0,8,,2.00E-19,A0JMU8,Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (XlMLN51),Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (XlMLN51),GO:0003723; GO:0008380; GO:0006397; GO:0051028; GO:0016607; GO:0000184; GO:0048471; GO:0006417,"RNA binding; RNA splicing; mRNA processing; mRNA transport; nuclear speck; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; perinuclear region of cytoplasm; regulation of translation",PF09405;,,,,,,,,,CASC3_XENLA,Xenopus laevis (African clawed frog),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]" comp140978_c0_seq2,1971,43.379,0.65413551,30,7,,2.00E-18,O15234,Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz),Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz),GO:0003723; GO:0008380; GO:0005829; GO:0035145; GO:0010467; GO:0042802; GO:0008298; GO:0006397; GO:0051028; GO:0016607; GO:0000184; GO:0048471; GO:0006417; GO:0006950; GO:0030529,"RNA binding; RNA splicing; cytosol; exon-exon junction complex; gene expression; identical protein binding; intracellular mRNA localization; mRNA processing; mRNA transport; nuclear speck; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; perinuclear region of cytoplasm; regulation of translation; response to stress; ribonucleoprotein complex",PF09405;,1.00E-25,CHOYP_BTZ.1.1,,,,,,,CASC3_HUMAN,Homo sapiens (Human),"intracellular mRNA localization [GO:0008298]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; termination of RNA polymerase II transcription [GO:0006369]" comp140979_c0_seq1,1832,32.9694,0.47136642,379,2077,,1.00E-42,Q9BGI1,"Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Peroxiredoxin V) (Prx-V) (Thioredoxin reductase)","Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Peroxiredoxin V) (Prx-V) (Thioredoxin reductase)",GO:0070995; GO:0001016; GO:0043027; GO:0031410; GO:0005829; GO:0042744; GO:0005739; GO:0043066; GO:0051354; GO:0016480; GO:0005634; GO:0048471; GO:0004601; GO:0005782; GO:0072541; GO:0032967; GO:2001057; GO:0060785,NADPH oxidation; RNA polymerase III regulatory region DNA binding; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasmic vesicle; cytosol; hydrogen peroxide catabolic process; mitochondrion; negative regulation of apoptotic process; negative regulation of oxidoreductase activity; negative regulation of transcription from RNA polymerase III promoter; nucleus; perinuclear region of cytoplasm; peroxidase activity; peroxisomal matrix; peroxynitrite reductase activity; positive regulation of collagen biosynthetic process; reactive nitrogen species metabolic process; regulation of apoptosis involved in tissue homeostasis,PF08534;,,,,,,,,,PRDX5_BOVIN,Bos taurus (Bovine),cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; NADPH oxidation [GO:0070995]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785] comp140987_c2_seq1,281,30.2491,0.47157788,4,7,,,,,,,,,,,1.00E-12,ruditapes_c26002,,,,,,, comp140988_c0_seq1,231,35.4978,0.56414431,4,0,,1.00E-08,Q5B778,Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase),GO:0007186; GO:0003723; GO:0048315; GO:0005737; GO:0000290; GO:0046872; GO:0075308; GO:0090305; GO:0005634; GO:0004535; GO:0006355; GO:0009847; GO:0006351; GO:0005993,"G-protein coupled receptor signaling pathway; RNA binding; conidium formation; cytoplasm; deadenylation-dependent decapping of nuclear-transcribed mRNA; metal ion binding; negative regulation of conidium formation; nucleic acid phosphodiester bond hydrolysis; nucleus; poly(A)-specific ribonuclease activity; regulation of transcription, DNA-dependent; spore germination; transcription, DNA-dependent; trehalose catabolic process",PF03372;PF12799;,4.00E-26,CHOYP_LOC100378486.1.1,,,,,,,CCR4_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp140988_c1_seq7,1780,38.4831,0.65285944,0,0,,3.00E-51,Q3KQF4,Leucine-rich repeat-containing protein 69,Leucine-rich repeat-containing protein 69,,,PF13855;,4.00E-75,CHOYP_LOC100378486.1.1,,,,,,,LRC69_XENLA,Xenopus laevis (African clawed frog), comp140988_c1_seq9,1719,38.1617,0.6235188,0,0,,2.00E-51,Q3KQF4,Leucine-rich repeat-containing protein 69,Leucine-rich repeat-containing protein 69,,,PF13855;,4.00E-75,CHOYP_LOC100378486.1.1,,,,,,,LRC69_XENLA,Xenopus laevis (African clawed frog), comp140989_c0_seq1,1780,33.9326,0.5740119,0,0,,,,,,,,,,,7.00E-89,ruditapes_c15432,,,,,,, comp140989_c0_seq3,1793,33.8539,0.57309998,0,0,,4.00E-78,Q8HXP7,"Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)","Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)",GO:0030145; GO:0005759; GO:0004784; GO:0006801,manganese ion binding; mitochondrial matrix; superoxide dismutase activity; superoxide metabolic process,PF02777;PF00081;,,,,,,,,,SODM_PANTR,Pan troglodytes (Chimpanzee), comp140989_c0_seq4,1793,33.8539,0.57220492,0,0,,4.00E-78,Q8HXP7,"Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)","Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)",GO:0030145; GO:0005759; GO:0004784; GO:0006801,manganese ion binding; mitochondrial matrix; superoxide dismutase activity; superoxide metabolic process,PF02777;PF00081;,9.00E-20,CHOYP_SODM.2.2,,,,,,,SODM_PANTR,Pan troglodytes (Chimpanzee), comp140994_c1_seq12,477,41.0901,0.35565633,113,213,,1.00E-22,B0K019,BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1),BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1),GO:0006915; GO:0005829; GO:0005739; GO:0043066; GO:0005634; GO:0048471; GO:0042493; GO:0010226; GO:0035094,apoptotic process; cytosol; mitochondrion; negative regulation of apoptotic process; nucleus; perinuclear region of cytoplasm; response to drug; response to lithium ion; response to nicotine,PF02179;PF00240;,,,2.00E-12,ruditapes_c26266,,,,,BAG1_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; response to drug [GO:0042493]; response to lithium ion [GO:0010226]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070] comp140995_c0_seq1,3379,43.504,0.46193799,22,123,,0,P54358,DNA polymerase delta catalytic subunit (EC 2.7.7.7),DNA polymerase delta catalytic subunit (EC 2.7.7.7),GO:0008296; GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0043625; GO:0046872; GO:0005875; GO:0022008; GO:0000166; GO:0006974,"3'-5'-exodeoxyribonuclease activity; 4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; delta DNA polymerase complex; metal ion binding; microtubule associated complex; neurogenesis; nucleotide binding; response to DNA damage stimulus",PF00136;PF03104;PF14260;,,,,,,,,,DPOD1_DROME,Drosophila melanogaster (Fruit fly),"base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication proofreading [GO:0045004]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; neurogenesis [GO:0022008]; nucleotide-excision repair, DNA gap filling [GO:0006297]; sensory perception of pain [GO:0019233]" comp140995_c0_seq2,3363,43.6218,0.4742339,14,141,,0,P28339,DNA polymerase delta catalytic subunit (EC 2.7.7.7),DNA polymerase delta catalytic subunit (EC 2.7.7.7),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0004527; GO:0046872; GO:0090305; GO:0000166; GO:0005634,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; exonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotide binding; nucleus",PF00136;PF03104;PF14260;,0,CHOYP_POLD1.1.1,,,,,,,DPOD1_BOVIN,Bos taurus (Bovine),"base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]" comp141000_c0_seq1,1853,39.7733,0.39924271,299,3227,,3.00E-33,Q6IQU7,Integrator complex subunit 12 (Int12),Integrator complex subunit 12 (Int12),GO:0005634; GO:0008270,nucleus; zinc ion binding,PF00628;,9.00E-33,CHOYP_CD109.1.2,1.00E-53,ruditapes_c537,,,,,INT12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141003_c1_seq1,3199,47.2648,0.55120538,6,7,,8.00E-80,Q9XV66,Protein unc-80 (Uncoordinated protein 80),Protein unc-80 (Uncoordinated protein 80),GO:0030424; GO:0005261; GO:0034703; GO:0055080; GO:0040017; GO:0042493,axon; cation channel activity; cation channel complex; cation homeostasis; positive regulation of locomotion; response to drug,PF15778;,7.00E-107,CHOYP_PHUM_PHUM244880.2.2,,,,,,,UNC80_CAEEL,Caenorhabditis elegans,cation homeostasis [GO:0055080]; positive regulation of locomotion [GO:0040017]; response to drug [GO:0042493] comp141003_c1_seq2,3218,47.3586,0.54564612,8,0,,6.00E-114,Q9VB11,Protein unc-80 homolog,Protein unc-80 homolog,GO:0005261; GO:0034703; GO:0055080,cation channel activity; cation channel complex; cation homeostasis,PF15778;,,,,,,,,,UNC80_DROME,Drosophila melanogaster (Fruit fly),cation homeostasis [GO:0055080]; locomotor rhythm [GO:0045475] comp141003_c1_seq3,1037,44.2623,0.47462321,0,0,,4.00E-60,Q9VB11,Protein unc-80 homolog,Protein unc-80 homolog,GO:0005261; GO:0034703; GO:0055080,cation channel activity; cation channel complex; cation homeostasis,PF15778;,,,,,,,,,UNC80_DROME,Drosophila melanogaster (Fruit fly),cation homeostasis [GO:0055080]; locomotor rhythm [GO:0045475] comp141003_c1_seq4,1056,44.8864,0.47210304,11,0,,2.00E-64,Q8BLN6,Protein unc-80 homolog (mUNC-80),Protein unc-80 homolog (mUNC-80),GO:0016021,integral to membrane,PF15778;,,,,,,,,,UNC80_MOUSE,Mus musculus (Mouse), comp141004_c1_seq1,955,44.6073,1.16471863,23,314,,3.00E-06,Q8K480,Membrane frizzled-related protein (Membrane-type frizzled-related protein),Membrane frizzled-related protein (Membrane-type frizzled-related protein),GO:0016021,integral to membrane,PF00431;PF01392;PF00057;,,,,,,,,,MFRP_MOUSE,Mus musculus (Mouse),eye photoreceptor cell development [GO:0042462]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601] comp141005_c0_seq1,1013,36.5252,0.47604283,0,90,,3.00E-16,Q15776,Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192),Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192),GO:0003677; GO:0005737; GO:0046872; GO:0005730; GO:0003700; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleolus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZN192_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp141005_c0_seq2,2128,35.4793,0.31738681,34,617,,1.00E-14,Q8TF20,Zinc finger protein 721,Zinc finger protein 721,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN721_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141006_c0_seq1,642,38.3178,0.38559529,3,0,,4.00E-31,Q08BY0,"NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Protein midA homolog, mitochondrial)","NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Protein midA homolog, mitochondrial)",GO:0032981; GO:0005739,mitochondrial respiratory chain complex I assembly; mitochondrion,PF02636;,,,,,,,,,MIDA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ATP metabolic process [GO:0046034]; chordate embryonic development [GO:0043009]; mitochondrial respiratory chain complex I assembly [GO:0032981] comp141006_c0_seq2,1583,42.3879,0.36134698,9,31,,5.00E-145,Q7L592,"NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Protein midA homolog, mitochondrial)","NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Protein midA homolog, mitochondrial)",GO:0008168; GO:0032981; GO:0005739,methyltransferase activity; mitochondrial respiratory chain complex I assembly; mitochondrion,PF02636;,,,,,,,,,MIDA_HUMAN,Homo sapiens (Human),ATP metabolic process [GO:0046034]; mitochondrial respiratory chain complex I assembly [GO:0032981] comp141006_c0_seq3,1128,42.9078,0.3351438,13,25,,,,,,,,,2.00E-25,CHOYP_LOC101171379.1.1,,,,,,,,, comp141008_c0_seq2,1169,43.2849,0.38626638,22,22,,2.00E-40,Q5R4Y2,Ran-binding protein 3 (RanBP3),Ran-binding protein 3 (RanBP3),GO:0005737; GO:0046907; GO:0005634; GO:0015031,cytoplasm; intracellular transport; nucleus; protein transport,PF00638;,,,,,,,,,RANB3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp141008_c0_seq4,1085,42.8571,0.38532246,3,6,,9.00E-41,Q4R4T9,Ran-binding protein 3 (RanBP3),Ran-binding protein 3 (RanBP3),GO:0005737; GO:0046907; GO:0005634; GO:0015031,cytoplasm; intracellular transport; nucleus; protein transport,PF00638;,9.00E-30,CHOYP_LOC591690.1.1,,,,,,,RANB3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp141009_c1_seq2,536,45.8955,1.18670473,24,0,,1.00E-19,P51865,Teratocarcinoma-derived growth factor (Cripto growth factor) (Epidermal growth factor-like Cripto protein),Teratocarcinoma-derived growth factor (Cripto growth factor) (Epidermal growth factor-like Cripto protein),GO:0030509; GO:0005794; GO:0000187; GO:0031225; GO:0008595; GO:0060070; GO:0055007; GO:0009986; GO:0015026; GO:0005615; GO:0019897; GO:0007369; GO:0008083; GO:0001701; GO:0001763; GO:0030512; GO:0038092; GO:0005634; GO:0048471; GO:0030335; GO:0001954; GO:0048146; GO:0045944; GO:0001570,"BMP signaling pathway; Golgi apparatus; activation of MAPK activity; anchored to membrane; anterior/posterior axis specification, embryo; canonical Wnt receptor signaling pathway; cardiac muscle cell differentiation; cell surface; coreceptor activity; extracellular space; extrinsic to plasma membrane; gastrulation; growth factor activity; in utero embryonic development; morphogenesis of a branching structure; negative regulation of transforming growth factor beta receptor signaling pathway; nodal signaling pathway; nucleus; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of cell-matrix adhesion; positive regulation of fibroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis",PF09443;,,,,,,,,,TDGF1_MOUSE,Mus musculus (Mouse),"activation of MAPK activity [GO:0000187]; anterior/posterior axis specification [GO:0009948]; anterior/posterior axis specification, embryo [GO:0008595]; BMP signaling pathway [GO:0030509]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle cell differentiation [GO:0055007]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to tumor necrosis factor [GO:0071356]; gastrulation [GO:0007369]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; morphogenesis of a branching structure [GO:0001763]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nodal signaling pathway [GO:0038092]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of signal transduction [GO:0009966]; vasculogenesis [GO:0001570]" comp141010_c0_seq2,2189,34.3079,0.59044739,27,187,,8.00E-30,Q9Y2V2,Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24),Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24),GO:0003677; GO:0043186; GO:0000932; GO:0005829; GO:0035556; GO:0003730; GO:0019902; GO:0043488; GO:0006355,"DNA binding; P granule; cytoplasmic mRNA processing body; cytosol; intracellular signal transduction; mRNA 3'-UTR binding; phosphatase binding; regulation of mRNA stability; regulation of transcription, DNA-dependent",PF00313;,,,1.00E-17,ruditapes_c13566,,,,,CHSP1_HUMAN,Homo sapiens (Human),"intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" comp141013_c0_seq1,2179,40.0642,0.57453101,16,35,,3.00E-75,Q58EN8,Vacuolar protein sorting-associated protein 33B,Vacuolar protein sorting-associated protein 33B,GO:0035622; GO:0031902; GO:0005765; GO:0015031; GO:0006904,intrahepatic bile duct development; late endosome membrane; lysosomal membrane; protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,VP33B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),intrahepatic bile duct development [GO:0035622]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp141013_c0_seq2,2155,40.0464,0.56970611,11,33,,0,Q96AX1,Vacuolar protein sorting-associated protein 33A (hVPS33A),Vacuolar protein sorting-associated protein 33A (hVPS33A),GO:0005769; GO:0005770; GO:0031902; GO:0005765; GO:0032418; GO:0032400; GO:0048471; GO:0030220; GO:0015031; GO:0048070; GO:0006904; GO:0016192,early endosome; late endosome; late endosome membrane; lysosomal membrane; lysosome localization; melanosome localization; perinuclear region of cytoplasm; platelet formation; protein transport; regulation of developmental pigmentation; vesicle docking involved in exocytosis; vesicle-mediated transport,PF00995;,,,,,,,,,VP33A_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; lysosome localization [GO:0032418]; melanosome localization [GO:0032400]; platelet formation [GO:0030220]; protein transport [GO:0015031]; regulation of developmental pigmentation [GO:0048070]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] comp141013_c0_seq3,812,43.1034,0.55931289,2,0,,,,,,,,,2.00E-106,CHOYP_VP33A.1.1,,,,,,,,, comp141015_c2_seq1,1767,41.3696,0.45502179,0,0,,,,,,,,,9.00E-128,CHOYP_LOC100371254.1.1,,,,,,,,, comp141015_c2_seq3,1758,41.5245,0.49230355,0,10,,2.00E-89,Q6PAM1,Alpha-taxilin,Alpha-taxilin,GO:0042113; GO:0005737; GO:0006887,B cell activation; cytoplasm; exocytosis,PF09728;,8.00E-128,CHOYP_LOC100371254.1.1,,,,,,,TXLNA_MOUSE,Mus musculus (Mouse),B cell activation [GO:0042113]; exocytosis [GO:0006887]; mitophagy in response to mitochondrial depolarization [GO:0098779] comp141015_c2_seq6,1812,41.2804,0.44605101,0,0,,3.00E-89,Q6PAM1,Alpha-taxilin,Alpha-taxilin,GO:0042113; GO:0005737; GO:0006887,B cell activation; cytoplasm; exocytosis,PF09728;,,,,,,,,,TXLNA_MOUSE,Mus musculus (Mouse),B cell activation [GO:0042113]; exocytosis [GO:0006887]; mitophagy in response to mitochondrial depolarization [GO:0098779] comp141016_c0_seq1,3620,41.8232,0.71410775,6,11,,4.00E-34,Q62165,Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)],Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)],GO:0006607; GO:0005604; GO:0071711; GO:0060445; GO:0005509; GO:0009279; GO:0071679; GO:0070938; GO:0005737; GO:0007016; GO:0005856; GO:0016011; GO:0060441; GO:0005615; GO:0030175; GO:0005925; GO:0016021; GO:0030027; GO:0006509; GO:0045121; GO:0034453; GO:0019048; GO:0002011; GO:0022011; GO:0043409; GO:0030336; GO:0051898; GO:0021682; GO:0033268; GO:0005654; GO:0045211; GO:0042383; GO:0008307,NLS-bearing protein import into nucleus; basement membrane; basement membrane organization; branching involved in salivary gland morphogenesis; calcium ion binding; cell outer membrane; commissural neuron axon guidance; contractile ring; cytoplasm; cytoskeletal anchoring at plasma membrane; cytoskeleton; dystroglycan complex; epithelial tube branching involved in lung morphogenesis; extracellular space; filopodium; focal adhesion; integral to membrane; lamellipodium; membrane protein ectodomain proteolysis; membrane raft; microtubule anchoring; modulation by virus of host morphology or physiology; morphogenesis of an epithelial sheet; myelination in peripheral nervous system; negative regulation of MAPK cascade; negative regulation of cell migration; negative regulation of protein kinase B signaling cascade; nerve maturation; node of Ranvier; nucleoplasm; postsynaptic membrane; sarcolemma; structural constituent of muscle,PF05454;,,,,,,,,,DAG1_MOUSE,Mus musculus (Mouse),basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; response to peptide hormone [GO:0043434]; Schwann cell development [GO:0014044] comp141016_c0_seq2,3590,41.7827,0.71507035,10,26,,,,,,,,,2.00E-25,CHOYP_LOC100368987.1.1,,,,,,,,, comp141017_c0_seq1,2675,40.7103,0.85173358,826,1586,,1.00E-89,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,6.00E-18,CHOYP_HSPA12A.18.27,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp141018_c0_seq1,1484,39.2857,0.57685543,4,30,,4.00E-51,Q566M1,Protein FAM76B,Protein FAM76B,,,PF16046;,,,,,,,,,FA76B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein desumoylation [GO:0016926] comp141019_c0_seq2,2234,40.197,0.58253109,18,66,,1.00E-55,Q8R2T8,General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon),General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon),GO:0003677; GO:0005634; GO:0035914; GO:0006351,"DNA binding; nucleus; skeletal muscle cell differentiation; transcription, DNA-dependent",PF09734;,,,,,,,,,TF3C5_MOUSE,Mus musculus (Mouse),"skeletal muscle cell differentiation [GO:0035914]; transcription, DNA-templated [GO:0006351]" comp141021_c1_seq1,2031,40.5219,0.31736657,277,1857,,4.00E-108,C3KYR4,Phosphoglycerate kinase (EC 2.7.2.3),Phosphoglycerate kinase (EC 2.7.2.3),GO:0005524; GO:0005737; GO:0006096; GO:0004618,ATP binding; cytoplasm; glycolysis; phosphoglycerate kinase activity,PF00162;,,,,,,,,,PGK_CLOB6,Clostridium botulinum (strain 657 / Type Ba4),glycolytic process [GO:0006096] comp141021_c1_seq2,2015,40.5459,0.332324,505,841,,7.00E-112,Q67SW6,Phosphoglycerate kinase (EC 2.7.2.3),Phosphoglycerate kinase (EC 2.7.2.3),GO:0005524; GO:0005737; GO:0006096; GO:0004618,ATP binding; cytoplasm; glycolysis; phosphoglycerate kinase activity,PF00162;,,,,,,,,,PGK_SYMTH,Symbiobacterium thermophilum (strain T / IAM 14863),glycolytic process [GO:0006096] comp141021_c1_seq3,1729,42.8571,0.31888236,9,294,,0,P91427,Probable phosphoglycerate kinase (EC 2.7.2.3),Probable phosphoglycerate kinase (EC 2.7.2.3),GO:0005524; GO:0005737; GO:0006096; GO:0004618,ATP binding; cytoplasm; glycolysis; phosphoglycerate kinase activity,PF00162;,2.00E-179,CHOYP_PGK1.1.1,,,,,,,PGK_CAEEL,Caenorhabditis elegans,glycolytic process [GO:0006096]; phosphorylation [GO:0016310] comp141022_c0_seq1,3037,36.648,0.45948279,166,512,,1.00E-21,Q2JVA4,Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],GO:0006048; GO:0003977; GO:0000902; GO:0005737; GO:0019134; GO:0009245; GO:0009103; GO:0000287; GO:0009252; GO:0008360,UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine diphosphorylase activity; cell morphogenesis; cytoplasm; glucosamine-1-phosphate N-acetyltransferase activity; lipid A biosynthetic process; lipopolysaccharide biosynthetic process; magnesium ion binding; peptidoglycan biosynthetic process; regulation of cell shape,PF03479;PF00132;PF12804;,,,,,,,,,GLMU_SYNJA,Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime),cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp141022_c0_seq2,1574,37.8018,0.46092543,0,4,,3.00E-22,Q2JII9,Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],GO:0006048; GO:0003977; GO:0000902; GO:0005737; GO:0019134; GO:0009245; GO:0009103; GO:0000287; GO:0009252; GO:0008360,UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine diphosphorylase activity; cell morphogenesis; cytoplasm; glucosamine-1-phosphate N-acetyltransferase activity; lipid A biosynthetic process; lipopolysaccharide biosynthetic process; magnesium ion binding; peptidoglycan biosynthetic process; regulation of cell shape,PF03479;PF00132;PF12804;,,,,,,,,,GLMU_SYNJB,Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime),cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp141022_c0_seq3,1425,37.4737,0.41400555,8,77,,1.00E-14,Q2JVA4,Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],GO:0006048; GO:0003977; GO:0000902; GO:0005737; GO:0019134; GO:0009245; GO:0009103; GO:0000287; GO:0009252; GO:0008360,UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine diphosphorylase activity; cell morphogenesis; cytoplasm; glucosamine-1-phosphate N-acetyltransferase activity; lipid A biosynthetic process; lipopolysaccharide biosynthetic process; magnesium ion binding; peptidoglycan biosynthetic process; regulation of cell shape,PF03479;PF00132;PF12804;,,,,,,,,,GLMU_SYNJA,Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime),cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp141023_c0_seq2,2281,37.4397,0.50587463,192,705,,4.00E-76,Q923G2,"DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (RPB17) (RPB8 homolog)","DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (RPB17) (RPB8 homolog)",GO:0003677; GO:0005736; GO:0005665; GO:0005666; GO:0003899; GO:0006366,"DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; transcription from RNA polymerase II promoter",PF03870;,8.00E-79,CHOYP_RPAB3.2.4,,,,,,,RPAB3_MOUSE,Mus musculus (Mouse),piRNA metabolic process [GO:0034587]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360] comp141025_c0_seq1,3216,40.7338,0.56832642,85,1384,,0,Q801S2,"Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II B) (Fp)","Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II B) (Fp)",GO:0050660; GO:0005743; GO:0022904; GO:0008177; GO:0006105; GO:0006099,flavin adenine dinucleotide binding; mitochondrial inner membrane; respiratory electron transport chain; succinate dehydrogenase (ubiquinone) activity; succinate metabolic process; tricarboxylic acid cycle,PF00890;PF02910;,,,,,,,,,DHSAB_XENLA,Xenopus laevis (African clawed frog),respiratory electron transport chain [GO:0022904]; succinate metabolic process [GO:0006105]; tricarboxylic acid cycle [GO:0006099] comp141025_c0_seq2,3181,40.9305,0.56896619,252,762,,3.00E-61,Q9K107,L-aspartate oxidase (LASPO) (EC 1.4.3.16) (Quinolinate synthase B),L-aspartate oxidase (LASPO) (EC 1.4.3.16) (Quinolinate synthase B),GO:0008734; GO:0044318; GO:0009435; GO:0005737,L-aspartate oxidase activity; L-aspartate:fumarate oxidoreductase activity; NAD biosynthetic process; cytoplasm,PF00890;,,,,,,,,,NADB_NEIMB,Neisseria meningitidis serogroup B (strain MC58),NAD biosynthetic process [GO:0009435] comp141025_c0_seq3,3130,41.0543,0.57539076,26,299,,0,Q801S2,"Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II B) (Fp)","Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II B) (Fp)",GO:0050660; GO:0005743; GO:0022904; GO:0008177; GO:0006105; GO:0006099,flavin adenine dinucleotide binding; mitochondrial inner membrane; respiratory electron transport chain; succinate dehydrogenase (ubiquinone) activity; succinate metabolic process; tricarboxylic acid cycle,PF00890;PF02910;,0,CHOYP_DHSAB.1.1,,,,,,,DHSAB_XENLA,Xenopus laevis (African clawed frog),respiratory electron transport chain [GO:0022904]; succinate metabolic process [GO:0006105]; tricarboxylic acid cycle [GO:0006099] comp141027_c0_seq1,1765,38.5269,0.84726865,34,1076,,2.00E-108,P42620,Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.-.-),Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.-.-),GO:0016491,oxidoreductase activity,PF13409;,,,,,,,,,YQJG_ECOLI,Escherichia coli (strain K12), comp141028_c1_seq1,461,46.8547,0.57422145,28,203,,9.00E-14,P41696,Asparagine-rich zinc finger protein AZF1,Asparagine-rich zinc finger protein AZF1,GO:0000978; GO:0001077; GO:0071322; GO:0005829; GO:0046872; GO:0005634; GO:0060237,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to carbohydrate stimulus; cytosol; metal ion binding; nucleus; regulation of fungal-type cell wall organization,PF13912;,,,,,,,,,AZF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp141029_c0_seq1,3445,39.6807,0.43280777,0,0,,1.00E-174,Q28I90,DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A),DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A),,,PF00400;,,,,,,,,,DCAF8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141029_c0_seq3,3348,39.5759,0.44856266,0,0,,6.00E-175,Q28I90,DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A),DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A),,,PF00400;,6.00E-133,CHOYP_BRAFLDRAFT_65670.1.1,,,,,,,DCAF8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141032_c0_seq3,333,39.039,0.23721805,22,215,,2.00E-22,Q0P3X8,Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4),Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4),GO:0071986; GO:0071230; GO:0005764; GO:0032008; GO:0061462; GO:0008361,Ragulator complex; cellular response to amino acid stimulus; lysosome; positive regulation of TOR signaling cascade; protein localization to lysosome; regulation of cell size,,3.00E-24,CHOYP_LOC100377128.1.1,,,,,,,CG059_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; protein localization to lysosome [GO:0061462]; regulation of cell size [GO:0008361] comp141033_c0_seq1,3164,43.0152,0.5231198,3,22,,3.00E-157,Q9D4H9,PHD finger protein 14,PHD finger protein 14,GO:0008270,zinc ion binding,PF00628;,,,,,,,,,PHF14_MOUSE,Mus musculus (Mouse),lung alveolus development [GO:0048286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp141033_c0_seq2,3190,42.7586,0.53216599,13,27,,,,,,,,,5.00E-140,CHOYP_PHF14.1.1,,,,,,,,, comp141033_c0_seq3,2798,45.1036,0.51044507,35,40,,1.00E-158,Q9D4H9,PHD finger protein 14,PHD finger protein 14,GO:0008270,zinc ion binding,PF00628;,,,,,,,,,PHF14_MOUSE,Mus musculus (Mouse),lung alveolus development [GO:0048286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp141033_c0_seq4,1413,46.7091,0.51396567,0,0,,1.00E-33,Q7YZH1,PHD finger protein rhinoceros,PHD finger protein rhinoceros,GO:0042051; GO:0042059; GO:0005634; GO:0008270,compound eye photoreceptor development; negative regulation of epidermal growth factor receptor signaling pathway; nucleus; zinc ion binding,PF10513;,1.00E-123,CHOYP_PHF14.1.1,,,,,,,RNO_DROME,Drosophila melanogaster (Fruit fly),compound eye photoreceptor development [GO:0042051]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp141034_c1_seq1,1270,44.1732,0.90566286,0,15,,,,,,,,,1.00E-17,CHOYP_ACDOPBH.8.9,,,,,,,,, comp141034_c1_seq4,2066,42.2072,1.03300005,58,177,,3.00E-31,Q9XTQ6,Tyramine beta-hydroxylase (EC 1.14.17.-),Tyramine beta-hydroxylase (EC 1.14.17.-),GO:0006584; GO:0030054; GO:0005507; GO:0004500; GO:0042136; GO:0045202; GO:0008021,catecholamine metabolic process; cell junction; copper ion binding; dopamine beta-monooxygenase activity; neurotransmitter biosynthetic process; synapse; synaptic vesicle,PF03712;PF01082;PF03351;,7.00E-16,CHOYP_ACDOPBH.4.9,,,,,,,TBH1_CAEEL,Caenorhabditis elegans,octopamine biosynthetic process [GO:0006589] comp141038_c0_seq1,2422,43.3939,0.57154661,16,0,,4.00E-174,Q4PZA2,Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),GO:0005794; GO:0033093; GO:0010815; GO:0010816; GO:0009986; GO:0043583; GO:0005769; GO:0042733; GO:0034959; GO:0009897; GO:0007507; GO:0016021; GO:0046872; GO:0004222; GO:0016486; GO:0048471; GO:0060037; GO:0001921; GO:0006508; GO:0010814,Golgi apparatus; Weibel-Palade body; bradykinin catabolic process; calcitonin catabolic process; cell surface; ear development; early endosome; embryonic digit morphogenesis; endothelin maturation; external side of plasma membrane; heart development; integral to membrane; metal ion binding; metalloendopeptidase activity; peptide hormone processing; perinuclear region of cytoplasm; pharyngeal system development; positive regulation of receptor recycling; proteolysis; substance P catabolic process,PF01431;PF05649;,2.00E-24,CHOYP_CLSTN1.1.1,7.00E-27,ruditapes_c9292,,,,,ECE1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; endothelin maturation [GO:0034959]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of vasodilation [GO:0042312]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; substance P catabolic process [GO:0010814] comp141038_c0_seq3,2463,42.3061,0.48201772,4,10,,4.00E-174,Q4PZA2,Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),GO:0005794; GO:0033093; GO:0010815; GO:0010816; GO:0009986; GO:0043583; GO:0005769; GO:0042733; GO:0034959; GO:0009897; GO:0007507; GO:0016021; GO:0046872; GO:0004222; GO:0016486; GO:0048471; GO:0060037; GO:0001921; GO:0006508; GO:0010814,Golgi apparatus; Weibel-Palade body; bradykinin catabolic process; calcitonin catabolic process; cell surface; ear development; early endosome; embryonic digit morphogenesis; endothelin maturation; external side of plasma membrane; heart development; integral to membrane; metal ion binding; metalloendopeptidase activity; peptide hormone processing; perinuclear region of cytoplasm; pharyngeal system development; positive regulation of receptor recycling; proteolysis; substance P catabolic process,PF01431;PF05649;,1.00E-25,CHOYP_NEMVEDRAFT_V1G229362.1.1,,,,,,,ECE1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; endothelin maturation [GO:0034959]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of vasodilation [GO:0042312]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; substance P catabolic process [GO:0010814] comp141038_c0_seq5,1990,42.9146,0.62341222,8,0,,8.00E-43,P23276,Kell blood group glycoprotein (EC 3.4.24.-) (CD antigen CD238),Kell blood group glycoprotein (EC 3.4.24.-) (CD antigen CD238),GO:0016021; GO:0046872; GO:0004222; GO:0005886; GO:0006508; GO:0042310,integral to membrane; metal ion binding; metalloendopeptidase activity; plasma membrane; proteolysis; vasoconstriction,PF01431;PF05649;,,,,,,,,,KELL_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; cellular magnesium ion homeostasis [GO:0010961]; myelination [GO:0042552]; negative regulation of potassium ion transmembrane transport [GO:1901380]; regulation of axon diameter [GO:0031133]; regulation of cell size [GO:0008361]; skeletal muscle fiber development [GO:0048741]; vasoconstriction [GO:0042310] comp141041_c0_seq3,1160,34.569,0.46563428,161,1286,,1.00E-40,Q5DC69,"10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10)","10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10)",GO:0005524; GO:0005759; GO:0006457,ATP binding; mitochondrial matrix; protein folding,PF00166;,,,4.00E-14,ruditapes_c8750,,,,,CH10_SCHJA,Schistosoma japonicum (Blood fluke),protein folding [GO:0006457] comp141044_c0_seq1,2658,36.6441,0.46029688,81,178,,0,Q498M4,WD repeat-containing protein 5,WD repeat-containing protein 5,GO:0005671; GO:0071339; GO:0048188; GO:0043966; GO:0051568; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0042800; GO:0035064; GO:0006355; GO:0001501; GO:0006351,"Ada2/Gcn5/Ada3 transcription activator complex; MLL1 complex; Set1C/COMPASS complex; histone H3 acetylation; histone H3-K4 methylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; histone methyltransferase activity (H3-K4 specific); methylated histone residue binding; regulation of transcription, DNA-dependent; skeletal system development; transcription, DNA-dependent",PF00400;,0,CHOYP_WDR5.2.3,,,,,,,WDR5_RAT,Rattus norvegicus (Rat),"histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]" comp141044_c0_seq2,1989,34.8919,0.40026829,3,26,,8.00E-14,Q8BU03,Periodic tryptophan protein 2 homolog,Periodic tryptophan protein 2 homolog,GO:0005737; GO:0005730,cytoplasm; nucleolus,PF04003;PF00400;,2.00E-167,CHOYP_WDR5.2.3,,,1.00E-63,CU685382.p.cg.6,9,,PWP2_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]" comp141047_c3_seq5,332,31.3253,0.12388505,0,23,,,,,,,,,,,7.00E-17,ruditapes_c13058,,,,,,, comp141049_c0_seq1,1185,40.1688,0.5460119,236,273,,,,,,,,,7.00E-19,CHOYP_LAMP1.1.3,1.00E-19,ruditapes2_c1642,,,,,,, comp141050_c1_seq5,342,38.3041,0.17376035,0,0,,,,,,,,,,,6.00E-11,ruditapes_c8773,,,,,,, comp141056_c1_seq4,2001,43.7781,0.63697121,0,0,,3.00E-146,Q9JJ09,Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (rNaPi IIb),Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (rNaPi IIb),GO:0007568; GO:0016324; GO:0031526; GO:0030643; GO:0016021; GO:0031528; GO:0042301; GO:0032355; GO:0009750; GO:0031402; GO:0015321; GO:0005436,aging; apical plasma membrane; brush border membrane; cellular phosphate ion homeostasis; integral to membrane; microvillus membrane; phosphate ion binding; response to estradiol stimulus; response to fructose stimulus; sodium ion binding; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity,PF02690;,2.00E-40,CHOYP_NPT2B.1.2,,,,,,,NPT2B_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular phosphate ion homeostasis [GO:0030643]; phosphate ion transport [GO:0006817]; response to estradiol [GO:0032355]; response to fructose [GO:0009750] comp141056_c1_seq5,496,48.5887,0.5847892,0,3,,,,,,,,,2.00E-16,CHOYP_SLC34A2.1.2,,,,,,,,, comp141056_c1_seq6,939,39.7231,0.7579344,0,0,,8.00E-54,Q9DBP0,Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2),Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2),GO:0007568; GO:0016324; GO:0005903; GO:0031526; GO:0030643; GO:0001701; GO:0016021; GO:0042301; GO:0032355; GO:0009750; GO:0031402; GO:0015321; GO:0005436,aging; apical plasma membrane; brush border; brush border membrane; cellular phosphate ion homeostasis; in utero embryonic development; integral to membrane; phosphate ion binding; response to estradiol stimulus; response to fructose stimulus; sodium ion binding; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity,PF02690;,,,,,,,,,NPT2B_MOUSE,Mus musculus (Mouse),cellular phosphate ion homeostasis [GO:0030643]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estrogen [GO:0043627] comp141057_c0_seq1,3362,36.7638,0.49861932,2870,17101,,0,P54612,Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha),Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha),GO:0003823; GO:0007059; GO:0000775; GO:0005829; GO:0070262; GO:0000159; GO:0004722; GO:0042981,"antigen binding; chromosome segregation; chromosome, centromeric region; cytosol; peptidyl-serine dephosphorylation; protein phosphatase type 2A complex; protein serine/threonine phosphatase activity; regulation of apoptotic process",PF02985;,0,CHOYP_2AAA.1.1,6.00E-150,ruditapes_c28901,,,,,2AAA_PIG,Sus scrofa (Pig),"chromosome segregation [GO:0007059]; female meiotic division [GO:0007143]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic sister chromatid separation [GO:0051306]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein complex assembly [GO:0006461]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]" comp141058_c0_seq1,1769,37.9876,0.43002929,282,1449,,5.00E-35,Q9NX58,Cell growth-regulating nucleolar protein,Cell growth-regulating nucleolar protein,GO:0046872; GO:0005730,metal ion binding; nucleolus,PF08790;,2.00E-21,CHOYP_MGC78792.1.1,,,,,,,LYAR_HUMAN,Homo sapiens (Human), comp141058_c1_seq1,1568,42.3469,0.44145801,21,153,,2.00E-06,A2AKY4,Zinc finger protein 804A,Zinc finger protein 804A,GO:0046872,metal ion binding,PF12171;,,,,,,,,,Z804A_MOUSE,Mus musculus (Mouse), comp141058_c1_seq2,1412,37.5354,0.19268191,21,28,,9.00E-06,A2AKY4,Zinc finger protein 804A,Zinc finger protein 804A,GO:0046872,metal ion binding,PF12171;,,,,,,,,,Z804A_MOUSE,Mus musculus (Mouse), comp141059_c0_seq2,2003,35.4468,0.4664918,262,567,,8.00E-59,Q071E0,N-lysine methyltransferase SETD8-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase SETD8-A) (EC 2.1.1.43) (SET domain-containing protein 8-A),N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A),GO:0051301; GO:0005694; GO:0009953; GO:0018024; GO:0007067; GO:0005634; GO:0010628; GO:0006355; GO:0006351,"cell division; chromosome; dorsal/ventral pattern formation; histone-lysine N-methyltransferase activity; mitosis; nucleus; positive regulation of gene expression; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,1.00E-32,CHOYP_SETD8.1.3,,,,,,,SET8A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141060_c0_seq2,2814,46.091,0.31475025,0,2,,2.00E-10,P51954,Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1),Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1),GO:0005524; GO:0051301; GO:0030030; GO:0005813; GO:0005737; GO:0046872; GO:0007067; GO:0005634; GO:0018108; GO:0004672; GO:0004674; GO:0004713; GO:0006974; GO:0010212,ATP binding; cell division; cell projection organization; centrosome; cytoplasm; metal ion binding; mitosis; nucleus; peptidyl-tyrosine phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; response to DNA damage stimulus; response to ionizing radiation,PF00069;,6.00E-37,CHOYP_NEK1.2.5,,,,,,,NEK1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0042384]; kidney development [GO:0001822]; mitotic nuclear division [GO:0007067]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283] comp141060_c0_seq6,666,46.3964,0.36344285,69,41,,4.00E-62,P51954,Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1),Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1),GO:0005524; GO:0051301; GO:0030030; GO:0005813; GO:0005737; GO:0046872; GO:0007067; GO:0005634; GO:0018108; GO:0004672; GO:0004674; GO:0004713; GO:0006974; GO:0010212,ATP binding; cell division; cell projection organization; centrosome; cytoplasm; metal ion binding; mitosis; nucleus; peptidyl-tyrosine phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; response to DNA damage stimulus; response to ionizing radiation,PF00069;,2.00E-61,CHOYP_NEK1.5.5,5.00E-28,ruditapes_c23900,,,,,NEK1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0042384]; kidney development [GO:0001822]; mitotic nuclear division [GO:0007067]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283] comp141061_c3_seq1,1772,31.9413,0.57593721,1522,3432,,,,,,,,,,,2.00E-12,ruditapes_c9560,,,,,,, comp141062_c0_seq1,1715,34.4023,0.20069243,112,863,,4.00E-22,Q9CRC3,UPF0235 protein C15orf40 homolog,UPF0235 protein C15orf40 homolog,,,PF02594;,,,,,,,,,CO040_MOUSE,Mus musculus (Mouse), comp141063_c0_seq3,1953,32.8213,0.59059725,19,99,,3.00E-15,Q17Q97,Uncharacterized protein C19orf60 homolog,Uncharacterized protein C19orf60 homolog,,,,1.00E-17,CHOYP_NEMVEDRAFT_V1G244077.1.1,,,,,,,CS060_BOVIN,Bos taurus (Bovine), comp141064_c0_seq10,1103,46.0562,0.36061065,0,0,,9.00E-66,O14578,Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0048699; GO:0035556; GO:0046872; GO:0007091; GO:0007067; GO:0000070; GO:0050774; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; generation of neurons; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitosis; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,1.00E-66,CHOYP_CIT.2.2,,,8.00E-69,AM865392.p.cg.6,7,,CTRO_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467] comp141064_c0_seq14,966,45.5487,0.40258999,0,0,,2.00E-19,O14578,Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0048699; GO:0035556; GO:0046872; GO:0007091; GO:0007067; GO:0000070; GO:0050774; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; generation of neurons; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitosis; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,,,,,,,,,CTRO_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467] comp141064_c0_seq3,1133,46.0724,0.35045353,0,0,,,,,,,,,5.00E-71,CHOYP_CIT.1.2,,,,,,,,, comp141064_c0_seq8,996,45.5823,0.38914949,0,0,,,,,,,,,4.00E-28,CHOYP_CIT.1.2,,,,,,,,, comp141065_c0_seq1,1980,34.1414,0.62855648,145,893,,,,,,,,,5.00E-11,CHOYP_BRAFLDRAFT_66942.1.2,,,,,,,,, comp141065_c1_seq1,1533,45.7273,0.81562407,0,350,female,6.00E-68,Q02154,Glutamine synthetase 2 (EC 6.3.1.2) (Glutamate--ammonia ligase II) (Glutamine synthetase II) (GSII),Glutamine synthetase 2 (EC 6.3.1.2) (Glutamate--ammonia ligase II) (Glutamine synthetase II) (GSII),GO:0005524; GO:0005737; GO:0004356; GO:0006542; GO:0009399,ATP binding; cytoplasm; glutamate-ammonia ligase activity; glutamine biosynthetic process; nitrogen fixation,PF00120;PF03951;,0,CHOYP_LOC100376272.3.4,,,,,,,GLNA2_RHILP,Rhizobium leguminosarum bv. phaseoli,glutamine biosynthetic process [GO:0006542]; nitrogen fixation [GO:0009399] comp141065_c1_seq2,1546,45.7956,0.84300483,0,0,,8.00E-166,Q04831,Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),GO:0005524; GO:0005737; GO:0004356; GO:0006542,ATP binding; cytoplasm; glutamate-ammonia ligase activity; glutamine biosynthetic process,PF00120;PF03951;,4.00E-175,CHOYP_GLNA2.1.4,,,,,,,GLNA_PANAR,Panulirus argus (Caribbean spiny lobster) (Palinurus argus),glutamine biosynthetic process [GO:0006542] comp141065_c1_seq3,2720,38.9338,1.03151501,0,0,,2.00E-165,Q8HZM5,Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase),Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase),GO:0005524; GO:0004351; GO:0004356; GO:0006542; GO:0005739,ATP binding; glutamate decarboxylase activity; glutamate-ammonia ligase activity; glutamine biosynthetic process; mitochondrion,PF00120;PF03951;,2.00E-163,CHOYP_GLNA2.2.4,,,,,,,GLNA_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),glutamine biosynthetic process [GO:0006542] comp141065_c1_seq4,1546,45.1488,0.89094611,0,0,,1.00E-10,Q9ZLW5,Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),GO:0005524; GO:0005737; GO:0004356; GO:0006542; GO:0009399,ATP binding; cytoplasm; glutamate-ammonia ligase activity; glutamine biosynthetic process; nitrogen fixation,PF00120;PF03951;,1.00E-150,CHOYP_GLNA.2.5,,,,,,,GLNA_HELPJ,Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99),glutamine biosynthetic process [GO:0006542]; nitrogen fixation [GO:0009399] comp141065_c1_seq5,1262,49.1284,0.86972635,0,11,,7.00E-151,Q874T6,Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase),Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase),GO:0005524; GO:0005737; GO:0004356; GO:0006542,ATP binding; cytoplasm; glutamate-ammonia ligase activity; glutamine biosynthetic process,PF00120;PF03951;,,,4.00E-103,ruditapes_c8130,,,,,GLNA_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),ammonia assimilation cycle [GO:0019676]; cellular response to nitrogen starvation [GO:0006995]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740] comp141065_c1_seq6,1284,47.352,0.86301452,0,0,,,,,,,,,0,CHOYP_LOC100376272.3.4,,,,,,,,, comp141065_c1_seq7,1568,43.9413,0.88630651,0,344,,0,Q04831,Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),GO:0005524; GO:0005737; GO:0004356; GO:0006542,ATP binding; cytoplasm; glutamate-ammonia ligase activity; glutamine biosynthetic process,PF00120;PF03951;,0,CHOYP_GLNA.3.5,,,,,,,GLNA_PANAR,Panulirus argus (Caribbean spiny lobster) (Palinurus argus),glutamine biosynthetic process [GO:0006542] comp141065_c1_seq8,2379,39.9327,1.05563854,0,0,,0,P20478,Glutamine synthetase 2 cytoplasmic (EC 6.3.1.2) (Glutamate--ammonia ligase 2),Glutamine synthetase 2 cytoplasmic (EC 6.3.1.2) (Glutamate--ammonia ligase 2),GO:0005524; GO:0005737; GO:0006538; GO:0004356; GO:0006542; GO:0045213; GO:0007416,ATP binding; cytoplasm; glutamate catabolic process; glutamate-ammonia ligase activity; glutamine biosynthetic process; neurotransmitter receptor metabolic process; synapse assembly,PF00120;PF03951;,3.00E-33,CHOYP_LOC100376272.2.4,,,,,,,GLNA2_DROME,Drosophila melanogaster (Fruit fly),glutamate catabolic process [GO:0006538]; glutamine biosynthetic process [GO:0006542]; neurotransmitter receptor metabolic process [GO:0045213]; synapse assembly [GO:0007416] comp141065_c1_seq9,2720,38.6029,1.07762391,0,0,,0,Q8HZM5,Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase),Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase),GO:0005524; GO:0004351; GO:0004356; GO:0006542; GO:0005739,ATP binding; glutamate decarboxylase activity; glutamate-ammonia ligase activity; glutamine biosynthetic process; mitochondrion,PF00120;PF03951;,0,CHOYP_LOC100376272.4.4,4.00E-11,ruditapes_c31409,,,,,GLNA_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),glutamine biosynthetic process [GO:0006542] comp141065_c2_seq3,1171,37.6601,0.89292545,6,59,,,,,,,,,1.00E-16,CHOYP_contig_032683,,,,,,,,, comp141066_c1_seq1,1326,38.1599,0.36147051,42,198,,1.00E-65,Q8K2C9,Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (Protein tyrosine phosphatase-like protein PTPLAD1) (Protein-tyrosine phosphatase-like A domain-containing protein 1),Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1),GO:0007249; GO:0007254; GO:0007266; GO:0005789; GO:0006633; GO:0016021; GO:0016829,I-kappaB kinase/NF-kappaB cascade; JNK cascade; Rho protein signal transduction; endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; lyase activity,PF04387;,2.00E-20,CHOYP_LOC100376136.1.1,,,,,,,HACD3_MOUSE,Mus musculus (Mouse),fatty acid elongation [GO:0030497]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; JNK cascade [GO:0007254]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of viral genome replication [GO:0045070]; Rho protein signal transduction [GO:0007266]; very long-chain fatty acid biosynthetic process [GO:0042761] comp141068_c0_seq1,2341,41.6062,0.94817831,1,1692,female>male,3.00E-78,Q12834,Cell division cycle protein 20 homolog (p55CDC),Cell division cycle protein 20 homolog (p55CDC),GO:0051488; GO:0031145; GO:0051301; GO:0005813; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0048471; GO:0008284; GO:0090129; GO:0031915; GO:0051437; GO:0016567; GO:0050773; GO:0040020; GO:0005819; GO:0000922,activation of anaphase-promoting complex activity; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; centrosome; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; perinuclear region of cytoplasm; positive regulation of cell proliferation; positive regulation of synapse maturation; positive regulation of synaptic plasticity; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein ubiquitination; regulation of dendrite development; regulation of meiosis; spindle; spindle pole,PF12894;PF00400;,1.00E-19,CHOYP_CDC20.1.1,,,,,,,CDC20_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]; sister chromatid cohesion [GO:0007062] comp141072_c0_seq1,3814,37.9654,0.6077173,0,0,,7.00E-117,Q26473,Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I),Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I),GO:0030154; GO:0016021; GO:0007399; GO:0004872,cell differentiation; integral to membrane; nervous system development; receptor activity,PF01403;,,,,,,,,,SEM1A_SCHAM,Schistocerca americana (American grasshopper),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp141072_c0_seq2,3519,38.2779,0.6305231,0,0,,3.00E-103,Q26972,Semaphorin-1A (Semaphorin-I),Semaphorin-1A (Semaphorin-I),GO:0030154; GO:0016021; GO:0007399; GO:0004872,cell differentiation; integral to membrane; nervous system development; receptor activity,PF01437;PF01403;,,,,,,,,,SEM1A_TRICF,Tribolium confusum (Confused flour beetle),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp141072_c0_seq4,2840,40,0.62788447,12,5,,2.00E-82,Q76KF0,Semaphorin-6D,Semaphorin-6D,GO:0005794; GO:0030154; GO:0016021; GO:0014912; GO:0005886; GO:0014911; GO:0004872; GO:0021591,Golgi apparatus; cell differentiation; integral to membrane; negative regulation of smooth muscle cell migration; plasma membrane; positive regulation of smooth muscle cell migration; receptor activity; ventricular system development,PF01437;PF01403;,,,,,,,,,SEM6D_MOUSE,Mus musculus (Mouse),negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell migration [GO:0001755]; positive regulation of smooth muscle cell migration [GO:0014911]; semaphorin-plexin signaling pathway [GO:0071526]; ventricular system development [GO:0021591] comp141072_c0_seq5,2545,40.7073,0.66491327,0,0,,3.00E-120,Q26473,Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I),Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I),GO:0030154; GO:0016021; GO:0007399; GO:0004872,cell differentiation; integral to membrane; nervous system development; receptor activity,PF01403;,,,,,,,,,SEM1A_SCHAM,Schistocerca americana (American grasshopper),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp141072_c0_seq7,2060,40.6796,0.58135894,0,0,,4.00E-63,Q26473,Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I),Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I),GO:0030154; GO:0016021; GO:0007399; GO:0004872,cell differentiation; integral to membrane; nervous system development; receptor activity,PF01403;,,,,,,,,,SEM1A_SCHAM,Schistocerca americana (American grasshopper),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp141074_c1_seq2,1953,45.5709,0.2774668,81,583,,8.00E-77,P37198,Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62),Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62),GO:0042169; GO:0005975; GO:0007569; GO:0008219; GO:0003682; GO:0019221; GO:0005737; GO:0015758; GO:0009755; GO:0051028; GO:0007077; GO:0043407; GO:0046580; GO:0043066; GO:0008285; GO:0042059; GO:0031965; GO:0005643; GO:0031074; GO:0006913; GO:0043123; GO:0045742; GO:0045893; GO:0015031; GO:0030159; GO:0046578; GO:0010827; GO:0030529; GO:0044281; GO:0000922; GO:0017056; GO:0046966; GO:0006351; GO:0055085; GO:0043130; GO:0016032,"SH2 domain binding; carbohydrate metabolic process; cell aging; cell death; chromatin binding; cytokine-mediated signaling pathway; cytoplasm; glucose transport; hormone-mediated signaling pathway; mRNA transport; mitotic nuclear envelope disassembly; negative regulation of MAP kinase activity; negative regulation of Ras protein signal transduction; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of epidermal growth factor receptor signaling pathway; nuclear membrane; nuclear pore; nucleocytoplasmic shuttling complex; nucleocytoplasmic transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; protein transport; receptor signaling complex scaffold activity; regulation of Ras protein signal transduction; regulation of glucose transport; ribonucleoprotein complex; small molecule metabolic process; spindle pole; structural constituent of nuclear pore; thyroid hormone receptor binding; transcription, DNA-dependent; transmembrane transport; ubiquitin binding; viral process",PF05064;,2.00E-60,CHOYP_NUP62L.1.1,5.00E-85,ruditapes_c16633,,,,,NUP62_HUMAN,Homo sapiens (Human),"cell aging [GO:0007569]; cell death [GO:0008219]; cell surface receptor signaling pathway [GO:0007166]; gene silencing by RNA [GO:0031047]; hormone-mediated signaling pathway [GO:0009755]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of programmed cell death [GO:0043069]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterotrimerization [GO:0070208]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of protein import into nucleus [GO:0042306]; regulation of Ras protein signal transduction [GO:0046578]; regulation of signal transduction [GO:0009966]; ribonucleoprotein complex export from nucleus [GO:0071426]; RNA export from nucleus [GO:0006405]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]" comp141075_c0_seq1,924,39.3939,0.64385876,0,0,,2.00E-10,Q9Y2K7,Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),GO:0070544; GO:0051864; GO:0000790; GO:0005654; GO:0006355; GO:0006351; GO:0045322; GO:0008270,"histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); nuclear chromatin; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent; unmethylated CpG binding; zinc ion binding",PF00646;PF02373;PF16866;PF02008;,,,,,,,,,KDM2A_HUMAN,Homo sapiens (Human),"double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141075_c0_seq2,2637,43.7619,0.57272958,0,0,,2.00E-155,Q8CDU4,F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13),F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13),,,PF12937;PF13516;,,,,,,,,,FXL13_MOUSE,Mus musculus (Mouse), comp141075_c0_seq3,885,39.435,0.64076347,0,0,,4.00E-11,Q9Y2K7,Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),GO:0070544; GO:0051864; GO:0000790; GO:0005654; GO:0006355; GO:0006351; GO:0045322; GO:0008270,"histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); nuclear chromatin; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent; unmethylated CpG binding; zinc ion binding",PF00646;PF02373;PF16866;PF02008;,,,,,,,,,KDM2A_HUMAN,Homo sapiens (Human),"double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141075_c0_seq4,2598,43.8414,0.57081308,0,0,,2.00E-157,Q8CDU4,F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13),F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13),,,PF12937;PF13516;,7.00E-156,CHOYP_LOC100372542.1.3,7.00E-40,ruditapes_c30289,,,,,FXL13_MOUSE,Mus musculus (Mouse), comp141075_c0_seq5,2654,43.6699,0.57114183,15,0,,3.00E-38,Q9C5D2,F-box/LRR-repeat protein 4 (AtFBL4),F-box/LRR-repeat protein 4 (AtFBL4),,,PF12937;PF13516;,,,,,,,,,FBL4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp141075_c0_seq6,733,45.7026,0.45086079,0,0,,2.00E-16,Q6NW95,F-box/LRR-repeat protein 15,F-box/LRR-repeat protein 15,GO:0000086; GO:0019005; GO:0031146; GO:0030282; GO:0005737; GO:0009953; GO:0030513; GO:0016567,G2/M transition of mitotic cell cycle; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; bone mineralization; cytoplasm; dorsal/ventral pattern formation; positive regulation of BMP signaling pathway; protein ubiquitination,PF00646;,5.00E-76,CHOYP_LOC100372542.2.3,,,,,,,FXL15_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp141075_c0_seq7,2623,43.8048,0.56617383,0,0,,3.00E-33,Q9QZH7,F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),GO:0005737,cytoplasm,PF12937;PF13516;,9.00E-155,CHOYP_LOC100372542.1.3,,,,,,,FXL20_RAT,Rattus norvegicus (Rat), comp141078_c0_seq3,1279,35.8874,0.46334429,6,12,,,,,,,,,,,4.00E-20,ruditapes_c1762,,,,,,, comp141080_c1_seq3,2642,44.8524,0.50523305,221,378,,7.00E-13,Q8K310,Matrin-3,Matrin-3,GO:0003723; GO:0016363; GO:0000166; GO:0008270,RNA binding; nuclear matrix; nucleotide binding; zinc ion binding,,,,,,,,,,MATR3_MOUSE,Mus musculus (Mouse),heart valve development [GO:0003170]; posttranscriptional regulation of gene expression [GO:0010608]; ventricular septum development [GO:0003281] comp141081_c0_seq2,1490,40.0671,0.45181839,111,413,,5.00E-124,O60563,Cyclin-T1 (CycT1) (Cyclin-T),Cyclin-T1 (CycT1) (Cyclin-T),GO:0003677; GO:0007049; GO:0051301; GO:0003682; GO:0019048; GO:0045944; GO:0050434; GO:0008024; GO:0006468; GO:0000079; GO:0017069; GO:0006368; GO:0006367; GO:0044212; GO:0007179; GO:0016032,DNA binding; cell cycle; cell division; chromatin binding; modulation by virus of host morphology or physiology; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; positive transcription elongation factor complex b; protein phosphorylation; regulation of cyclin-dependent protein serine/threonine kinase activity; snRNA binding; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription regulatory region DNA binding; transforming growth factor beta receptor signaling pathway; viral process,PF00134;,9.00E-89,CHOYP_AAEL_AAEL004839.1.1,,,,,,,CCNT1_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; viral process [GO:0016032] comp141085_c0_seq2,1607,44.4306,0.48584714,243,6,,1.00E-86,Q80TT2,BAI1-associated protein 3 (BAP3),BAI1-associated protein 3 (BAP3),,,PF00168;PF10540;,1.00E-93,CHOYP_ISCW_ISCW005596.1.1,,,,,,,BAIP3_MOUSE,Mus musculus (Mouse),G-protein coupled receptor signaling pathway [GO:0007186] comp141085_c0_seq3,2213,45.549,0.57013038,155,8,,3.00E-99,O94812,BAI1-associated protein 3 (BAP3),BAI1-associated protein 3 (BAP3),GO:0007186; GO:0007269; GO:0008022,G-protein coupled receptor signaling pathway; neurotransmitter secretion; protein C-terminus binding,PF00168;PF10540;,,,,,,,,,BAIP3_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; neurotransmitter secretion [GO:0007269] comp141086_c0_seq1,1229,39.1375,0.51986509,167,525,,6.00E-125,Q5M7W7,"Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)","Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)",GO:0005524; GO:0005759; GO:0004827; GO:0006433,ATP binding; mitochondrial matrix; proline-tRNA ligase activity; prolyl-tRNA aminoacylation,PF03129;PF00587;,3.00E-12,CHOYP_SYPM.1.1,,,,,,,SYPM_RAT,Rattus norvegicus (Rat),prolyl-tRNA aminoacylation [GO:0006433] comp141086_c0_seq2,327,37.3089,0.36679124,7,49,,,,,,,,,9.00E-11,CHOYP_SYPM.1.1,,,,,,,,, comp141089_c0_seq1,1702,38.3079,0.91923327,30,326,,,,,,,,,7.00E-78,CHOYP_NIT2B.1.1,,,,,,,,, comp141089_c0_seq2,1686,38.3749,0.94127979,67,423,,1.00E-148,Q28IE5,Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2),Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2),GO:0005737; GO:0006807; GO:0050152,cytoplasm; nitrogen compound metabolic process; omega-amidase activity,PF00795;,7.00E-78,CHOYP_NIT2B.1.1,2.00E-39,ruditapes_c28266,,,,,NIT2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),nitrogen compound metabolic process [GO:0006807] comp141092_c0_seq1,2564,40.3276,0.58777244,295,432,,9.00E-66,Q5FWF5,N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1),N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1),GO:0000785; GO:0046872; GO:0000278; GO:0005654; GO:0034421; GO:0006275; GO:0007062; GO:0016746,"chromatin; metal ion binding; mitotic cell cycle; nucleoplasm; post-translational protein acetylation; regulation of DNA replication; sister chromatid cohesion; transferase activity, transferring acyl groups",PF13880;PF13878;,1.00E-32,CHOYP_ESCO1.1.1,,,,,,,ESCO1_HUMAN,Homo sapiens (Human),post-translational protein acetylation [GO:0034421]; regulation of DNA replication [GO:0006275]; sister chromatid cohesion [GO:0007062] comp141093_c0_seq1,958,41.6493,0.36528735,27,62,,2.00E-66,Q54DD3,"Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)","Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)",GO:0004047; GO:0006546; GO:0005739; GO:0008483,aminomethyltransferase activity; glycine catabolic process; mitochondrion; transaminase activity,PF01571;PF08669;,,,,,,,,,GCST_DICDI,Dictyostelium discoideum (Slime mold),glycine catabolic process [GO:0006546] comp141093_c0_seq2,965,41.658,0.38639076,11,46,,4.00E-89,Q8CFA2,"Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)","Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)",GO:0004047; GO:0006546; GO:0005739; GO:0008483,aminomethyltransferase activity; glycine catabolic process; mitochondrion; transaminase activity,PF01571;PF08669;,5.00E-52,CHOYP_GCST.1.1,,,,,,,GCST_MOUSE,Mus musculus (Mouse),glycine decarboxylation via glycine cleavage system [GO:0019464] comp141093_c0_seq3,532,43.2331,0.40412608,46,163,,2.00E-31,Q24TH3,Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein),Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein),GO:0004047; GO:0005737; GO:0006546; GO:0008483,aminomethyltransferase activity; cytoplasm; glycine catabolic process; transaminase activity,PF01571;PF08669;,,,,,,,,,GCST_DESHY,Desulfitobacterium hafniense (strain Y51),glycine decarboxylation via glycine cleavage system [GO:0019464] comp141096_c4_seq1,2770,37.87,0.82791776,66,4999,,1.00E-128,Q8MPM1,Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2),Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2),GO:0051693; GO:0005737; GO:0005856,actin filament capping; cytoplasm; cytoskeleton,PF00626;,2.00E-63,CHOYP_LOC100642024.1.2,7.00E-47,ruditapes2_c802,,,,,GELS2_LUMTE,Lumbricus terrestris (Common earthworm),actin filament capping [GO:0051693] comp141098_c0_seq3,1666,42.557,0.65773689,0,0,,4.00E-65,Q84G06,Phosphonopyruvate hydrolase (PPH) (EC 3.11.1.3),Phosphonopyruvate hydrolase (PPH) (EC 3.11.1.3),GO:0046872; GO:0033978,metal ion binding; phosphonopyruvate hydrolase activity,,0,CHOYP_PEPM.1.1,,,,,,,PPHA_VARSP,Variovorax sp. (strain Pal2), comp141098_c0_seq4,1606,42.8394,0.67237946,9,122,,0,P56839,Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9),Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9),GO:0046872; GO:0032923; GO:0050188,metal ion binding; organic phosphonate biosynthetic process; phosphoenolpyruvate mutase activity,,0,CHOYP_PEPM.1.1,,,6.00E-99,AM862974.p.cg.6,4,,PEPM_MYTED,Mytilus edulis (Blue mussel),organic phosphonate biosynthetic process [GO:0032923] comp141099_c0_seq1,449,44.098,0.61288937,0,5,,2.00E-06,C0ZW79,Phosphoglucosamine mutase (EC 5.4.2.10),Phosphoglucosamine mutase (EC 5.4.2.10),GO:0005975; GO:0000287; GO:0008966,carbohydrate metabolic process; magnesium ion binding; phosphoglucosamine mutase activity,PF02878;PF02879;PF02880;PF00408;,,,,,,,,,GLMM_RHOE4,Rhodococcus erythropolis (strain PR4 / NBRC 100887),carbohydrate metabolic process [GO:0005975] comp141099_c0_seq2,1743,44.6931,0.40766727,27,357,,0,O95394,Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3),Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3),GO:0006048; GO:0005829; GO:0006488; GO:0009790; GO:0006041; GO:0019255; GO:0030097; GO:0000287; GO:0004610; GO:0004614; GO:0043687; GO:0018279; GO:0007283,UDP-N-acetylglucosamine biosynthetic process; cytosol; dolichol-linked oligosaccharide biosynthetic process; embryo development; glucosamine metabolic process; glucose 1-phosphate metabolic process; hemopoiesis; magnesium ion binding; phosphoacetylglucosamine mutase activity; phosphoglucomutase activity; post-translational protein modification; protein N-linked glycosylation via asparagine; spermatogenesis,PF02878;PF00408;,9.00E-58,CHOYP_BRAFLDRAFT_285738.1.1,,,,,,,AGM1_HUMAN,Homo sapiens (Human),glucosamine metabolic process [GO:0006041]; glucose 1-phosphate metabolic process [GO:0019255]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp141101_c2_seq1,2290,38.4279,0.51633997,94,507,,4.00E-180,P13667,Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72),Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72),GO:0045454; GO:0009986; GO:0005788; GO:0006662; GO:0042470; GO:0003756; GO:0015035; GO:0009306,cell redox homeostasis; cell surface; endoplasmic reticulum lumen; glycerol ether metabolic process; melanosome; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein secretion,PF00085;,1.00E-56,CHOYP_PDIA4.1.1,,,,,,,PDIA4_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976] comp141101_c2_seq2,989,38.5238,0.38732434,8,126,,,,,,,,,,,3.00E-84,ruditapes_c29008,,,,,,, comp141103_c2_seq2,3562,35.7945,0.58841179,4428,8590,,5.00E-16,Q8C2Q3,RNA-binding protein 14 (RNA-binding motif protein 14),RNA-binding protein 14 (RNA-binding motif protein 14),GO:0003723; GO:0016575; GO:0030374; GO:0005730; GO:0000166; GO:0045944; GO:0005667; GO:0006351,"RNA binding; histone deacetylation; ligand-dependent nuclear receptor transcription coactivator activity; nucleolus; nucleotide binding; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent",PF00076;,,,,,,,,,RBM14_MOUSE,Mus musculus (Mouse),"centriole assembly [GO:0098534]; histone deacetylation [GO:0016575]; negative regulation of centriole replication [GO:0046600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]" comp141104_c1_seq2,1310,34.6565,0.48757075,0,0,,4.00E-38,Q4VSI4,Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),GO:0016605; GO:0004197; GO:0005737; GO:0010216; GO:0007275; GO:0005634; GO:0043065; GO:0016579; GO:0042803; GO:0031647; GO:0051090; GO:0006283; GO:0004221; GO:0006511; GO:0004843,PML body; cysteine-type endopeptidase activity; cytoplasm; maintenance of DNA methylation; multicellular organismal development; nucleus; positive regulation of apoptotic process; protein deubiquitination; protein homodimerization activity; regulation of protein stability; regulation of sequence-specific DNA binding transcription factor activity; transcription-coupled nucleotide-excision repair; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00917;PF00443;PF14533;PF12436;,,,,,,,,,UBP7_RAT,Rattus norvegicus (Rat),maintenance of DNA methylation [GO:0010216]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141104_c1_seq3,3397,39.7409,0.40626498,0,0,,2.00E-41,Q24574,Ubiquitin carboxyl-terminal hydrolase 64E (EC 3.4.19.12) (Ubiquitin thioesterase 64E) (Ubiquitin-specific-processing protease 64E) (Deubiquitinating enzyme 64E),Ubiquitin carboxyl-terminal hydrolase 64E (EC 3.4.19.12) (Ubiquitin thioesterase 64E) (Ubiquitin-specific-processing protease 64E) (Deubiquitinating enzyme 64E),GO:0042675; GO:0008234; GO:0005737; GO:0005634; GO:0016579; GO:0050821; GO:0031935; GO:0004221; GO:0006511,compound eye cone cell differentiation; cysteine-type peptidase activity; cytoplasm; nucleus; protein deubiquitination; protein stabilization; regulation of chromatin silencing; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,0,CHOYP_LOC100749463.1.1,,,,,,,UBPE_DROME,Drosophila melanogaster (Fruit fly),base-excision repair [GO:0006284]; compound eye cone cell differentiation [GO:0042675]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of chromatin silencing [GO:0031935]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141104_c1_seq4,4531,38.1814,0.40959027,0,0,,2.00E-16,Q7RTZ2,Putative ubiquitin carboxyl-terminal hydrolase 17-like protein 1 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 1) (Ubiquitin thioesterase 17-like protein 1) (Ubiquitin-specific-processing protease 17-like protein 1),Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 1) (Ubiquitin thioesterase 17-like protein 1) (Ubiquitin-specific-processing protease 17-like protein 1),GO:0006915; GO:0008234; GO:0005783; GO:0005634; GO:0004221; GO:0006511,apoptotic process; cysteine-type peptidase activity; endoplasmic reticulum; nucleus; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,U17L1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141104_c1_seq5,4516,38.1532,0.41182548,0,0,,0,Q4VSI4,Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),GO:0016605; GO:0004197; GO:0005737; GO:0010216; GO:0007275; GO:0005634; GO:0043065; GO:0016579; GO:0042803; GO:0031647; GO:0051090; GO:0006283; GO:0004221; GO:0006511; GO:0004843,PML body; cysteine-type endopeptidase activity; cytoplasm; maintenance of DNA methylation; multicellular organismal development; nucleus; positive regulation of apoptotic process; protein deubiquitination; protein homodimerization activity; regulation of protein stability; regulation of sequence-specific DNA binding transcription factor activity; transcription-coupled nucleotide-excision repair; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00917;PF00443;PF14533;PF12436;,0,CHOYP_LOC100749463.1.1,,,,,,,UBP7_RAT,Rattus norvegicus (Rat),maintenance of DNA methylation [GO:0010216]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141104_c1_seq9,3382,39.7102,0.40903049,0,0,,0,Q4VSI4,Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7),GO:0016605; GO:0004197; GO:0005737; GO:0010216; GO:0007275; GO:0005634; GO:0043065; GO:0016579; GO:0042803; GO:0031647; GO:0051090; GO:0006283; GO:0004221; GO:0006511; GO:0004843,PML body; cysteine-type endopeptidase activity; cytoplasm; maintenance of DNA methylation; multicellular organismal development; nucleus; positive regulation of apoptotic process; protein deubiquitination; protein homodimerization activity; regulation of protein stability; regulation of sequence-specific DNA binding transcription factor activity; transcription-coupled nucleotide-excision repair; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00917;PF00443;PF14533;PF12436;,0,CHOYP_LOC100749463.1.1,,,,,,,UBP7_RAT,Rattus norvegicus (Rat),maintenance of DNA methylation [GO:0010216]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141109_c0_seq1,3138,39.675,0.61563956,24,45,,4.00E-138,Q91WG5,5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2),5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2),GO:0043531; GO:0004679; GO:0031588; GO:0005524; GO:0004862; GO:0008603; GO:0005829; GO:0006633; GO:0005977; GO:0007243; GO:0008607; GO:0010800; GO:0030295; GO:0019217; GO:0006110,ADP binding; AMP-activated protein kinase activity; AMP-activated protein kinase complex; ATP binding; cAMP-dependent protein kinase inhibitor activity; cAMP-dependent protein kinase regulator activity; cytosol; fatty acid biosynthetic process; glycogen metabolic process; intracellular protein kinase cascade; phosphorylase kinase regulator activity; positive regulation of peptidyl-threonine phosphorylation; protein kinase activator activity; regulation of fatty acid metabolic process; regulation of glycolysis,PF00571;,5.00E-108,CHOYP_LOC100373594.1.1,,,,,,,AAKG2_MOUSE,Mus musculus (Mouse),fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; mitochondrion organization [GO:0007005]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; regulation of fatty acid metabolic process [GO:0019217]; regulation of glycolytic process [GO:0006110] comp141109_c0_seq3,1095,36.4384,0.60784562,0,0,,,,,,,,,,,4.00E-39,ruditapes_c27297,,,,,,, comp141109_c0_seq5,1862,44.1998,0.67134758,0,0,,9.00E-143,Q91WG5,5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2),5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2),GO:0043531; GO:0004679; GO:0031588; GO:0005524; GO:0004862; GO:0008603; GO:0005829; GO:0006633; GO:0005977; GO:0007243; GO:0008607; GO:0010800; GO:0030295; GO:0019217; GO:0006110,ADP binding; AMP-activated protein kinase activity; AMP-activated protein kinase complex; ATP binding; cAMP-dependent protein kinase inhibitor activity; cAMP-dependent protein kinase regulator activity; cytosol; fatty acid biosynthetic process; glycogen metabolic process; intracellular protein kinase cascade; phosphorylase kinase regulator activity; positive regulation of peptidyl-threonine phosphorylation; protein kinase activator activity; regulation of fatty acid metabolic process; regulation of glycolysis,PF00571;,,,,,,,,,AAKG2_MOUSE,Mus musculus (Mouse),fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; mitochondrion organization [GO:0007005]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; regulation of fatty acid metabolic process [GO:0019217]; regulation of glycolytic process [GO:0006110] comp141109_c0_seq6,1285,43.1128,0.53770302,0,15,,2.00E-51,P12904,5'-AMP-activated protein kinase subunit gamma (AMPK gamma) (AMPK subunit gamma) (Regulatory protein CAT3) (Sucrose non-fermenting protein 4),5'-AMP-activated protein kinase subunit gamma (AMPK gamma) (AMPK subunit gamma) (Regulatory protein CAT3) (Sucrose non-fermenting protein 4),GO:0031588; GO:0005524; GO:0005975; GO:0003824; GO:0005737; GO:0005641; GO:0007031; GO:0005886; GO:0045722; GO:0006468; GO:0043539; GO:0006357; GO:0001302; GO:0006351,"AMP-activated protein kinase complex; ATP binding; carbohydrate metabolic process; catalytic activity; cytoplasm; nuclear envelope lumen; peroxisome organization; plasma membrane; positive regulation of gluconeogenesis; protein phosphorylation; protein serine/threonine kinase activator activity; regulation of transcription from RNA polymerase II promoter; replicative cell aging; transcription, DNA-dependent",PF00571;,5.00E-110,CHOYP_LOC100373594.1.1,,,,,,,AAKG_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"carbohydrate metabolic process [GO:0005975]; peroxisome organization [GO:0007031]; positive regulation of gluconeogenesis [GO:0045722]; protein phosphorylation [GO:0006468]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; replicative cell aging [GO:0001302]; transcription, DNA-templated [GO:0006351]" comp141109_c0_seq7,449,42.9844,0.59524105,0,0,,4.00E-06,Q59011,Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205),Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205),GO:0006177; GO:0003938; GO:0030554; GO:0046872,GMP biosynthetic process; IMP dehydrogenase activity; adenyl nucleotide binding; metal ion binding,PF00571;PF00478;,,,,,,,,,IMDH_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),GMP biosynthetic process [GO:0006177] comp141109_c0_seq8,2481,38.5732,0.50958422,0,0,,2.00E-138,Q9UGJ0,5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p),5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p),GO:0043531; GO:0031588; GO:0005524; GO:0006754; GO:0004862; GO:0008603; GO:0006853; GO:0007050; GO:0044255; GO:0005829; GO:0006633; GO:0005977; GO:0008286; GO:0007243; GO:0005654; GO:0008607; GO:0010800; GO:0030295; GO:0019901; GO:0042304; GO:0046320; GO:0046324; GO:0006110; GO:0016126,ADP binding; AMP-activated protein kinase complex; ATP binding; ATP biosynthetic process; cAMP-dependent protein kinase inhibitor activity; cAMP-dependent protein kinase regulator activity; carnitine shuttle; cell cycle arrest; cellular lipid metabolic process; cytosol; fatty acid biosynthetic process; glycogen metabolic process; insulin receptor signaling pathway; intracellular protein kinase cascade; nucleoplasm; phosphorylase kinase regulator activity; positive regulation of peptidyl-threonine phosphorylation; protein kinase activator activity; protein kinase binding; regulation of fatty acid biosynthetic process; regulation of fatty acid oxidation; regulation of glucose import; regulation of glycolysis; sterol biosynthetic process,PF00571;,,,,,,,,,AAKG2_HUMAN,Homo sapiens (Human),ATP biosynthetic process [GO:0006754]; carnitine shuttle [GO:0006853]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; macroautophagy [GO:0016236]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid metabolic process [GO:0019217]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose import [GO:0046324]; regulation of glycolytic process [GO:0006110]; regulation of signal transduction by p53 class mediator [GO:1901796]; sterol biosynthetic process [GO:0016126] comp141110_c1_seq1,2837,42.6859,0.57408883,255,262,,2.00E-56,Q9M086,DDB1- and CUL4-associated factor homolog 1 (Protein DDB1-CUL4 ASSOCIATED FACTOR 1) (Protein DCAF1),DDB1- and CUL4-associated factor homolog 1 (Protein DDB1-CUL4 ASSOCIATED FACTOR 1) (Protein DCAF1),GO:0080008; GO:0009793; GO:0009908; GO:0048366; GO:0005634; GO:0016567,Cul4-RING ubiquitin ligase complex; embryo development ending in seed dormancy; flower development; leaf development; nucleus; protein ubiquitination,PF08513;,7.00E-11,CHOYP_LOC662115.2.2,,,,,,,DCAF1_ARATH,Arabidopsis thaliana (Mouse-ear cress),embryo development ending in seed dormancy [GO:0009793]; flower development [GO:0009908]; fruit development [GO:0010154]; leaf development [GO:0048366]; phyllome development [GO:0048827]; protein ubiquitination [GO:0016567]; shoot system development [GO:0048367] comp141110_c2_seq1,1814,45.9206,0.5152607,225,49,,2.00E-176,Q9Y4B6,Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Vpr-interacting protein),Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein),GO:0005737; GO:0019048; GO:0005634; GO:0016567,cytoplasm; modulation by virus of host morphology or physiology; nucleus; protein ubiquitination,,3.00E-172,CHOYP_VPRBP.1.1,,,,,,,VPRBP_HUMAN,Homo sapiens (Human),"B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; histone H2A-T120 phosphorylation [GO:1990245]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]; V(D)J recombination [GO:0033151]; viral process [GO:0016032]" comp141111_c1_seq1,1396,36.8195,0.3655944,0,23,,3.00E-41,Q5XKA2,"Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)","Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)",GO:0016021; GO:0005744; GO:0030150,integral to membrane; mitochondrial inner membrane presequence translocase complex; protein import into mitochondrial matrix,PF08294;,,,,,,,,,TIM21_XENLA,Xenopus laevis (African clawed frog),protein import into mitochondrial matrix [GO:0030150] comp141111_c1_seq3,1343,37.1556,0.33054617,35,271,,2.00E-41,Q5XKA2,"Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)","Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)",GO:0016021; GO:0005744; GO:0030150,integral to membrane; mitochondrial inner membrane presequence translocase complex; protein import into mitochondrial matrix,PF08294;,,,,,,,,,TIM21_XENLA,Xenopus laevis (African clawed frog),protein import into mitochondrial matrix [GO:0030150] comp141111_c1_seq4,1284,37.1495,0.36745804,33,41,,2.00E-38,Q3SZV6,"Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)","Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)",GO:0016021; GO:0005744; GO:0032981; GO:0033617; GO:0030150,integral to membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial respiratory chain complex I assembly; mitochondrial respiratory chain complex IV assembly; protein import into mitochondrial matrix,PF08294;,,,4.00E-20,ruditapes_c25874,,,,,TIM21_BOVIN,Bos taurus (Bovine),mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; protein import into mitochondrial matrix [GO:0030150] comp141113_c3_seq1,1674,29.2115,0.58852584,33,18,,2.00E-51,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,3.00E-63,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp141113_c3_seq2,1370,29.2701,0.51182207,43,93,,2.00E-52,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,1.00E-35,CHOYP_LOC100562878.1.2,5.00E-20,ruditapes_c17285,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp141113_c3_seq3,499,27.6553,0.75091484,0,0,,,,,,,,,2.00E-21,CHOYP_contig_026738,,,,,,,,, comp141113_c4_seq1,697,27.1162,0.23741545,18,27,,,,,,,,,1.00E-12,CHOYP_BRAFLDRAFT_199990.1.3,,,,,,,,, comp141115_c0_seq1,1396,39.6848,0.53924611,265,1532,,2.00E-89,P47816,Programmed cell death protein 2 (Zinc finger protein Rp-8),Programmed cell death protein 2 (Zinc finger protein Rp-8),GO:0003677; GO:0006915; GO:0005737; GO:0046872; GO:0005634; GO:0012501,DNA binding; apoptotic process; cytoplasm; metal ion binding; nucleus; programmed cell death,PF04194;PF01753;,,,,,,,,,PDCD2_RAT,Rattus norvegicus (Rat),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; programmed cell death [GO:0012501]; regulation of hematopoietic progenitor cell differentiation [GO:1901532] comp141116_c0_seq1,2156,42.8108,0.93482213,136,1396,,4.00E-25,Q08882,Probable nuclear hormone receptor HR3 (mHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (mHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0005634; GO:0043565; GO:0003707; GO:0004887; GO:0008270,nucleus; sequence-specific DNA binding; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,2.00E-15,CHOYP_LOC100378940.1.1,,,,,,,HR3_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),"transcription, DNA-templated [GO:0006351]" comp141117_c0_seq1,1851,39.9244,0.74883866,339,340,,1.00E-60,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp141119_c0_seq1,2074,41.8997,0.37620656,259,874,,0,O93257,X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP/AP lyase Ku70) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (DNA repair protein XRCC6) (Ku autoantigen protein p70 homolog) (Ku70),X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP/AP lyase Ku70) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (DNA repair protein XRCC6) (Ku autoantigen protein p70 homolog) (Ku70),GO:0051575; GO:0005524; GO:0004003; GO:0006310; GO:0043564; GO:0005694; GO:0003684; GO:0006303; GO:0045892; GO:0070419; GO:0005654; GO:0000723; GO:0042162; GO:0006351,"5'-deoxyribose-5-phosphate lyase activity; ATP binding; ATP-dependent DNA helicase activity; DNA recombination; Ku70:Ku80 complex; chromosome; damaged DNA binding; double-strand break repair via nonhomologous end joining; negative regulation of transcription, DNA-dependent; nonhomologous end joining complex; nucleoplasm; telomere maintenance; telomeric DNA binding; transcription, DNA-dependent",PF02735;PF03730;PF03731;PF02037;,6.00E-175,CHOYP_BRAFLDRAFT_281658.1.1,,,,,,,XRCC6_CHICK,Gallus gallus (Chicken),"cellular response to gamma radiation [GO:0071480]; cellular response to X-ray [GO:0071481]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of transcription, DNA-templated [GO:0045892]; telomere maintenance [GO:0000723]; transcription, DNA-templated [GO:0006351]" comp141121_c0_seq1,651,41.7819,0.72967549,63,99,,1.00E-15,P25992,Yemanuclein-alpha,Yemanuclein-alpha,GO:0003677; GO:0000777; GO:0007143; GO:0035042; GO:0042585; GO:0000776; GO:0001940; GO:0005654,"DNA binding; condensed chromosome kinetochore; female meiosis; fertilization, exchange of chromosomal proteins; germinal vesicle; kinetochore; male pronucleus; nucleoplasm",PF08729;PF14075;,3.00E-14,CHOYP_LOC100370569.1.1,,,,,,,YEMA_DROME,Drosophila melanogaster (Fruit fly),"female meiotic division [GO:0007143]; fertilization, exchange of chromosomal proteins [GO:0035042]; oogenesis [GO:0048477]" comp141121_c2_seq1,3612,42.8848,0.37946116,34,110,,1.00E-24,E1B7L7,Ubinuclein-2,Ubinuclein-2,GO:0005634,nucleus,PF08729;PF14075;,,,,,,,,,UBN2_BOVIN,Bos taurus (Bovine), comp141121_c2_seq2,3348,43.0108,0.36177752,30,91,,4.00E-23,Q6ZU65,Ubinuclein-2,Ubinuclein-2,GO:0005634,nucleus,PF08729;PF14075;,,,,,,,,,UBN2_HUMAN,Homo sapiens (Human), comp141121_c2_seq3,3072,43.3594,0.38817051,0,0,,1.00E-24,E1B7L7,Ubinuclein-2,Ubinuclein-2,GO:0005634,nucleus,PF08729;PF14075;,,,,,,,,,UBN2_BOVIN,Bos taurus (Bovine), comp141122_c0_seq1,704,30.6818,0.5496849,86,248,,,,,,,,,,,2.00E-15,ruditapes_c17805,,,,,,, comp141123_c0_seq2,2646,43.2729,0.38776076,0,0,,4.00E-121,Q9H8E8,Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP),Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP),GO:0005671; GO:0030274; GO:0022402; GO:0005737; GO:0009790; GO:0043966; GO:0004402,Ada2/Gcn5/Ada3 transcription activator complex; LIM domain binding; cell cycle process; cytoplasm; embryo development; histone H3 acetylation; histone acetyltransferase activity,PF13673;,4.00E-102,CHOYP_BRAFLDRAFT_127142.1.1,,,,,,,CSR2B_HUMAN,Homo sapiens (Human),G2/M transition of mitotic cell cycle [GO:0000086]; histone H3 acetylation [GO:0043966] comp141123_c0_seq3,1605,42.6168,0.37073277,0,0,,8.00E-12,Q5R7T9,Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2),Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2),GO:0003677; GO:0035098; GO:0016568; GO:0005737; GO:0035064; GO:0061086; GO:0000122; GO:0061087; GO:0045944; GO:0007379; GO:0019827; GO:0008270,DNA binding; ESC/E(Z) complex; chromatin modification; cytoplasm; methylated histone residue binding; negative regulation of histone H3-K27 methylation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone H3-K27 methylation; positive regulation of transcription from RNA polymerase II promoter; segment specification; stem cell maintenance; zinc ion binding,PF14061;PF00628;,,,,,,,,,MTF2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),chromatin modification [GO:0016568]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] comp141125_c0_seq1,1779,40.1911,0.33480684,210,2520,,1.00E-112,Q8K203,Endonuclease 8-like 3 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase FPG2) (DNA glycosylase/AP lyase Neil3) (Endonuclease VIII-like 3) (Nei-like protein 3),Endonuclease 8-like 3 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase FPG2) (DNA glycosylase/AP lyase Neil3) (Endonuclease VIII-like 3) (Nei-like protein 3),GO:0019104; GO:0003906; GO:0006284; GO:0000405; GO:0003684; GO:0003690; GO:0006289; GO:0005634; GO:0003697; GO:0008270,DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; base-excision repair; bubble DNA binding; damaged DNA binding; double-stranded DNA binding; nucleotide-excision repair; nucleus; single-stranded DNA binding; zinc ion binding,PF06831;PF06839;PF00641;,2.00E-33,CHOYP_NEIL3.3.3,,,,,,,NEIL3_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289] comp141126_c2_seq1,1898,40.411,0.56960177,7,1010,female>male,2.00E-21,Q9H251,Cadherin-23 (Otocadherin),Cadherin-23 (Otocadherin),GO:0005509; GO:0006816; GO:0016339; GO:0051480; GO:0050957; GO:0007156; GO:0016021; GO:0016020; GO:0045494; GO:0005886; GO:0050896; GO:0050953; GO:0007605; GO:0032420; GO:0007601,calcium ion binding; calcium ion transport; calcium-dependent cell-cell adhesion; cytosolic calcium ion homeostasis; equilibrioception; homophilic cell adhesion; integral to membrane; membrane; photoreceptor cell maintenance; plasma membrane; response to stimulus; sensory perception of light stimulus; sensory perception of sound; stereocilium; visual perception,PF00028;,,,,,,,,,CAD23_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp141128_c0_seq3,1396,42.765,0.88726625,22,681,,3.00E-90,P48637,Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase),Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase),GO:0005524; GO:0007568; GO:0005829; GO:0043295; GO:1901687; GO:0004363; GO:0016594; GO:0000287; GO:0007399; GO:0042803; GO:0043200; GO:0046686; GO:0031667; GO:0006979; GO:0034612; GO:0006805,ATP binding; aging; cytosol; glutathione binding; glutathione derivative biosynthetic process; glutathione synthase activity; glycine binding; magnesium ion binding; nervous system development; protein homodimerization activity; response to amino acid stimulus; response to cadmium ion; response to nutrient levels; response to oxidative stress; response to tumor necrosis factor; xenobiotic metabolic process,PF03917;PF03199;,,,,,,,,,GSHB_HUMAN,Homo sapiens (Human),aging [GO:0007568]; cellular amino acid metabolic process [GO:0006520]; glutathione biosynthetic process [GO:0006750]; nervous system development [GO:0007399]; response to amino acid [GO:0043200]; response to cadmium ion [GO:0046686]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to xenobiotic stimulus [GO:0009410] comp141129_c0_seq1,3517,35.9966,0.47532813,33,170,,1.00E-20,Q5R902,Histone deacetylase 5 (HD5) (EC 3.5.1.98),Histone deacetylase 5 (HD5) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0000118; GO:0046872; GO:0005634; GO:0010830; GO:0006355; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase complex; metal ion binding; nucleus; regulation of myotube differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12203;PF00850;,0,CHOYP_BRAFLDRAFT_217516.1.1,,,,,,,HDAC5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of gene expression, epigenetic [GO:0040029]; regulation of myotube differentiation [GO:0010830]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141129_c0_seq2,3485,36.0689,0.4510046,72,269,,0,Q94517,Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98),Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98),GO:0035098; GO:0031523; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016581; GO:0016580; GO:0007350; GO:0006342; GO:0005737; GO:0070983; GO:0008340; GO:0070932; GO:0070933; GO:0004407; GO:0007517; GO:0050771; GO:2001229; GO:0000122; GO:0048477; GO:0005705; GO:0022904; GO:0003714; GO:0008134; GO:0006351; GO:0006099,"ESC/E(Z) complex; Myb complex; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); NuRD complex; Sin3 complex; blastoderm segmentation; chromatin silencing; cytoplasm; dendrite guidance; determination of adult lifespan; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; muscle organ development; negative regulation of axonogenesis; negative regulation of response to gamma radiation; negative regulation of transcription from RNA polymerase II promoter; oogenesis; polytene chromosome interband; respiratory electron transport chain; transcription corepressor activity; transcription factor binding; transcription, DNA-dependent; tricarboxylic acid cycle",PF00850;,,,2.00E-92,ruditapes_c24776,,,,,HDAC1_DROME,Drosophila melanogaster (Fruit fly),"blastoderm segmentation [GO:0007350]; chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; gene silencing [GO:0016458]; histone deacetylation [GO:0016575]; muscle organ development [GO:0007517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of response to gamma radiation [GO:2001229]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of histone acetylation [GO:0035065]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]; tricarboxylic acid cycle [GO:0006099]" comp141129_c0_seq3,3537,36.0758,0.44447787,0,0,,2.00E-20,Q9UBN7,Histone deacetylase 6 (HD6) (EC 3.5.1.98),Histone deacetylase 6 (HD6) (EC 3.5.1.98),GO:0070846; GO:0051879; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016235; GO:0070842; GO:0043014; GO:0005901; GO:0031252; GO:0070301; GO:0071218; GO:0035967; GO:0005881; GO:0005829; GO:0070840; GO:0019899; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0032418; GO:0016236; GO:0005874; GO:0005875; GO:0008017; GO:0006515; GO:0010727; GO:0007026; GO:0051354; GO:0043242; GO:0045861; GO:0045892; GO:0034983; GO:0048471; GO:0031593; GO:0070845; GO:0090035; GO:0010634; GO:1901300; GO:0010870; GO:0009967; GO:0043241; GO:0000209; GO:0060765; GO:0070201; GO:0060632; GO:0010469; GO:0070848; GO:0051788; GO:0009636; GO:0048156; GO:0006351; GO:0042903; GO:0043162; GO:0008270,"Hsp90 deacetylation; Hsp90 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); aggresome; aggresome assembly; alpha-tubulin binding; caveola; cell leading edge; cellular response to hydrogen peroxide; cellular response to misfolded protein; cellular response to topologically incorrect protein; cytoplasmic microtubule; cytosol; dynein complex binding; enzyme binding; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; lysosome localization; macroautophagy; microtubule; microtubule associated complex; microtubule binding; misfolded or incompletely synthesized protein catabolic process; negative regulation of hydrogen peroxide metabolic process; negative regulation of microtubule depolymerization; negative regulation of oxidoreductase activity; negative regulation of protein complex disassembly; negative regulation of proteolysis; negative regulation of transcription, DNA-dependent; peptidyl-lysine deacetylation; perinuclear region of cytoplasm; polyubiquitin binding; polyubiquitinated misfolded protein transport; positive regulation of chaperone-mediated protein complex assembly; positive regulation of epithelial cell migration; positive regulation of hydrogen peroxide-mediated programmed cell death; positive regulation of receptor biosynthetic process; positive regulation of signal transduction; protein complex disassembly; protein polyubiquitination; regulation of androgen receptor signaling pathway; regulation of establishment of protein localization; regulation of microtubule-based movement; regulation of receptor activity; response to growth factor stimulus; response to misfolded protein; response to toxic substance; tau protein binding; transcription, DNA-dependent; tubulin deacetylase activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; zinc ion binding",PF00850;PF02148;,,,,,,,,,HDAC6_HUMAN,Homo sapiens (Human),"aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; organelle organization [GO:0006996]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of microtubule-based movement [GO:0060632]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]" comp141129_c0_seq4,3561,35.8888,0.46373832,0,0,,2.00E-20,Q5R902,Histone deacetylase 5 (HD5) (EC 3.5.1.98),Histone deacetylase 5 (HD5) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0000118; GO:0046872; GO:0005634; GO:0010830; GO:0006355; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase complex; metal ion binding; nucleus; regulation of myotube differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12203;PF00850;,0,CHOYP_BRAFLDRAFT_217516.1.1,,,,,,,HDAC5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of gene expression, epigenetic [GO:0040029]; regulation of myotube differentiation [GO:0010830]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141129_c0_seq6,3529,35.9309,0.45790752,0,0,,0,Q94517,Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98),Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98),GO:0035098; GO:0031523; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016581; GO:0016580; GO:0007350; GO:0006342; GO:0005737; GO:0070983; GO:0008340; GO:0070932; GO:0070933; GO:0004407; GO:0007517; GO:0050771; GO:2001229; GO:0000122; GO:0048477; GO:0005705; GO:0022904; GO:0003714; GO:0008134; GO:0006351; GO:0006099,"ESC/E(Z) complex; Myb complex; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); NuRD complex; Sin3 complex; blastoderm segmentation; chromatin silencing; cytoplasm; dendrite guidance; determination of adult lifespan; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; muscle organ development; negative regulation of axonogenesis; negative regulation of response to gamma radiation; negative regulation of transcription from RNA polymerase II promoter; oogenesis; polytene chromosome interband; respiratory electron transport chain; transcription corepressor activity; transcription factor binding; transcription, DNA-dependent; tricarboxylic acid cycle",PF00850;,,,,,,,,,HDAC1_DROME,Drosophila melanogaster (Fruit fly),"blastoderm segmentation [GO:0007350]; chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; gene silencing [GO:0016458]; histone deacetylation [GO:0016575]; muscle organ development [GO:0007517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of response to gamma radiation [GO:2001229]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of histone acetylation [GO:0035065]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]; tricarboxylic acid cycle [GO:0006099]" comp141129_c0_seq7,3569,36.0045,0.45983468,0,0,,1.00E-20,Q5R902,Histone deacetylase 5 (HD5) (EC 3.5.1.98),Histone deacetylase 5 (HD5) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0000118; GO:0046872; GO:0005634; GO:0010830; GO:0006355; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase complex; metal ion binding; nucleus; regulation of myotube differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12203;PF00850;,0,CHOYP_BRAFLDRAFT_217516.1.1,,,,,,,HDAC5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of gene expression, epigenetic [GO:0040029]; regulation of myotube differentiation [GO:0010830]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141129_c0_seq8,3581,36.0514,0.44831042,0,0,,0,Q94517,Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98),Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98),GO:0035098; GO:0031523; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016581; GO:0016580; GO:0007350; GO:0006342; GO:0005737; GO:0070983; GO:0008340; GO:0070932; GO:0070933; GO:0004407; GO:0007517; GO:0050771; GO:2001229; GO:0000122; GO:0048477; GO:0005705; GO:0022904; GO:0003714; GO:0008134; GO:0006351; GO:0006099,"ESC/E(Z) complex; Myb complex; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); NuRD complex; Sin3 complex; blastoderm segmentation; chromatin silencing; cytoplasm; dendrite guidance; determination of adult lifespan; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; muscle organ development; negative regulation of axonogenesis; negative regulation of response to gamma radiation; negative regulation of transcription from RNA polymerase II promoter; oogenesis; polytene chromosome interband; respiratory electron transport chain; transcription corepressor activity; transcription factor binding; transcription, DNA-dependent; tricarboxylic acid cycle",PF00850;,0,CHOYP_BRAFLDRAFT_217516.1.1,4.00E-13,ruditapes_c7769,,,,,HDAC1_DROME,Drosophila melanogaster (Fruit fly),"blastoderm segmentation [GO:0007350]; chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; gene silencing [GO:0016458]; histone deacetylation [GO:0016575]; muscle organ development [GO:0007517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of response to gamma radiation [GO:2001229]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of histone acetylation [GO:0035065]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]; tricarboxylic acid cycle [GO:0006099]" comp141131_c0_seq3,1960,44.1327,0.57788973,0,0,,5.00E-22,Q589G5,Protogenin,Protogenin,GO:0016021; GO:0007275,integral to membrane; multicellular organismal development,PF00041;PF07679;,,,,,,,,,PRTG_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275] comp141131_c0_seq7,2488,44.0514,0.5570968,1,110,,7.00E-141,P20241,Neuroglian,Neuroglian,GO:0008366; GO:0048675; GO:0005509; GO:0061343; GO:0048036; GO:0048813; GO:0007173; GO:0060857; GO:0008050; GO:0030175; GO:0007560; GO:0016021; GO:0016328; GO:0008049; GO:0035011; GO:0016319; GO:0021682; GO:0007158; GO:0005919; GO:0045924; GO:0035151; GO:0019991; GO:0050808; GO:0005923,"axon ensheathment; axon extension; calcium ion binding; cell adhesion involved in heart morphogenesis; central complex development; dendrite morphogenesis; epidermal growth factor receptor signaling pathway; establishment of glial blood-brain barrier; female courtship behavior; filopodium; imaginal disc morphogenesis; integral to membrane; lateral plasma membrane; male courtship behavior; melanotic encapsulation of foreign target; mushroom body development; nerve maturation; neuron cell-cell adhesion; pleated septate junction; regulation of female receptivity; regulation of tube size, open tracheal system; septate junction assembly; synapse organization; tight junction",PF13882;PF00041;PF07679;PF00047;,,,3.00E-69,ruditapes_c16500,,,,,NRG_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" comp141131_c2_seq1,1341,37.3602,0.45381668,233,1429,,3.00E-12,Q5R795,Mitochondrial fission factor,Mitochondrial fission factor,GO:0016021; GO:0000266; GO:0008053; GO:0005741; GO:0005777; GO:0090141; GO:0090314; GO:0042803,integral to membrane; mitochondrial fission; mitochondrial fusion; mitochondrial outer membrane; peroxisome; positive regulation of mitochondrial fission; positive regulation of protein targeting to membrane; protein homodimerization activity,PF05644;,,,,,,,,,MFF_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mitochondrial fission [GO:0000266]; mitochondrial fusion [GO:0008053]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314] comp141132_c1_seq2,2309,36.7692,0.43909483,1,54,,,,,,,,,8.00E-41,CHOYP_BRAFLDRAFT_64464.2.2,,,,,,,,, comp141132_c1_seq3,1905,37.8478,0.41401364,0,34,,4.00E-66,Q5RAS2,Nucleoporin GLE1 (GLE1-like protein),Nucleoporin GLE1 (GLE1-like protein),GO:0005737; GO:0005643; GO:0016973; GO:0015031,cytoplasm; nuclear pore; poly(A)+ mRNA export from nucleus; protein transport,PF07817;,,,,,,,,,GLE1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] comp141132_c2_seq10,474,43.4599,0.78512746,0,0,,,,,,,,,6.00E-28,CHOYP_NFAT5.1.1,,,,,,,,, comp141132_c2_seq7,1004,46.2151,0.68784646,42,10,,7.00E-98,Q9WV30,Nuclear factor of activated T-cells 5 (NF-AT5) (Rel domain-containing transcription factor NFAT5) (T-cell transcription factor NFAT5),Nuclear factor of activated T-cells 5 (NF-AT5) (Rel domain-containing transcription factor NFAT5) (T-cell transcription factor NFAT5),GO:0003677; GO:0001816; GO:0005737; GO:0005634; GO:0045944; GO:0070884; GO:0003700; GO:0006351,"DNA binding; cytokine production; cytoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of calcineurin-NFAT signaling cascade; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF16179;PF00554;,6.00E-51,CHOYP_NFAT5.1.1,,,,,,,NFAT5_MOUSE,Mus musculus (Mouse),"cytokine production [GO:0001816]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; transcription, DNA-templated [GO:0006351]" comp141135_c0_seq1,2463,43.1587,0.42099875,160,607,,2.00E-138,Q08D69,Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16),Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11635;,,,,,,,,,MED16_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp141137_c1_seq10,4183,48.8884,0.54371948,0,0,,,,,,,,,9.00E-31,CHOYP_LOC100559941.2.2,,,,,,,,, comp141137_c1_seq4,4210,50,0.53979605,0,0,,,,,,,,,9.00E-31,CHOYP_LOC100559941.2.2,,,,,,,,, comp141137_c1_seq8,4253,48.9302,0.5372456,0,0,,,,,,,,,9.00E-31,CHOYP_LOC100559941.2.2,,,,,,,,, comp141137_c5_seq1,613,47.1452,0.67927069,311,251,,6.00E-22,Q5TM26,Protein PRRC2A (HLA-B-associated transcript 2) (Proline-rich and coiled-coil-containing protein 2A),Protein PRRC2A (HLA-B-associated transcript 2) (Proline-rich and coiled-coil-containing protein 2A),GO:0005737; GO:0005634,cytoplasm; nucleus,PF07001;,1.00E-62,CHOYP_LOC100559941.2.2,,,,,,,PRC2A_MACMU,Macaca mulatta (Rhesus macaque),cell differentiation [GO:0030154] comp141138_c1_seq1,1621,37.0759,0.43791499,446,2240,,5.00E-26,Q5XIY4,"Protein ACN9 homolog, mitochondrial","Succinate dehydrogenase assembly factor 3, mitochondrial (SDH assembly factor 3) (SDHAF3)",GO:0005739,mitochondrion,,1.00E-11,CHOYP_CG14898.1.1,1.00E-34,ruditapes_c1772,,,,,ACN9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141144_c0_seq1,3007,45.0283,0.58196151,4,10,,,,,,,,,5.00E-19,CHOYP_ISCW_ISCW022658.2.2,,,,,,,,, comp141144_c0_seq2,4283,44.805,0.47678948,53,174,,4.00E-63,Q15468,SCL-interrupting locus protein (TAL-1-interrupting locus protein),SCL-interrupting locus protein (TAL-1-interrupting locus protein),GO:0008283; GO:0005813; GO:0005829; GO:0000578; GO:0033504; GO:0030900; GO:0001947; GO:0001701; GO:0035264; GO:0043066; GO:0001843; GO:0030903; GO:0007224,cell proliferation; centrosome; cytosol; embryonic axis specification; floor plate development; forebrain development; heart looping; in utero embryonic development; multicellular organism growth; negative regulation of apoptotic process; neural tube closure; notochord development; smoothened signaling pathway,PF15253;,2.00E-65,CHOYP_LOC100368156.1.1,,,,,,,STIL_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224] comp141144_c0_seq3,3113,44.6193,0.57928956,0,0,,,,,,,,,6.00E-19,CHOYP_ISCW_ISCW022658.2.2,,,,,,,,, comp141148_c0_seq1,2743,40.6854,0.66768764,979,11,male>female,6.00E-45,Q4V7A9,Uncharacterized protein KIAA0895-like,Uncharacterized protein KIAA0895-like,,,PF08014;,1.00E-78,CHOYP_LOC753836.1.1,,,,,,,K895L_RAT,Rattus norvegicus (Rat), comp141150_c0_seq3,1815,35.7576,0.38039392,34,24,,1.00E-72,O14735,CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase),CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase),GO:0046341; GO:0003881; GO:0000139; GO:0043178; GO:0030246; GO:0019992; GO:0005789; GO:0016021; GO:0030145; GO:0006661; GO:0005886; GO:0044281,CDP-diacylglycerol metabolic process; CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; Golgi membrane; alcohol binding; carbohydrate binding; diacylglycerol binding; endoplasmic reticulum membrane; integral to membrane; manganese ion binding; phosphatidylinositol biosynthetic process; plasma membrane; small molecule metabolic process,PF01066;,7.00E-66,CHOYP_CDIPT.1.1,,,,,,,CDIPT_HUMAN,Homo sapiens (Human),CDP-diacylglycerol metabolic process [GO:0046341]; phosphatidylinositol biosynthetic process [GO:0006661] comp141150_c0_seq4,1979,35.7251,0.41322192,9,63,,4.00E-72,O14735,CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase),CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase),GO:0046341; GO:0003881; GO:0000139; GO:0043178; GO:0030246; GO:0019992; GO:0005789; GO:0016021; GO:0030145; GO:0006661; GO:0005886; GO:0044281,CDP-diacylglycerol metabolic process; CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; Golgi membrane; alcohol binding; carbohydrate binding; diacylglycerol binding; endoplasmic reticulum membrane; integral to membrane; manganese ion binding; phosphatidylinositol biosynthetic process; plasma membrane; small molecule metabolic process,PF01066;,7.00E-66,CHOYP_CDIPT.1.1,,,,,,,CDIPT_HUMAN,Homo sapiens (Human),CDP-diacylglycerol metabolic process [GO:0046341]; phosphatidylinositol biosynthetic process [GO:0006661] comp141151_c0_seq3,2153,39.3869,0.44332831,234,1798,,1.00E-148,Q3TAE8,"Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6 homolog) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)","Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6 homolog) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)",GO:0005789; GO:0016021; GO:0006486; GO:0016758,"endoplasmic reticulum membrane; integral to membrane; protein glycosylation; transferase activity, transferring hexosyl groups",PF03155;,1.00E-82,CHOYP_ALG6.1.1,,,,,,,ALG6_MOUSE,Mus musculus (Mouse),oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] comp141155_c0_seq1,1839,36.6504,0.47185759,11,11,,4.00E-84,A5D9C6,Repressor of RNA polymerase III transcription MAF1 homolog,Repressor of RNA polymerase III transcription MAF1 homolog,GO:0001030; GO:0001031; GO:0001032; GO:0005737; GO:0016480; GO:0005634; GO:0006351,"RNA polymerase III type 1 promoter DNA binding; RNA polymerase III type 2 promoter DNA binding; RNA polymerase III type 3 promoter DNA binding; cytoplasm; negative regulation of transcription from RNA polymerase III promoter; nucleus; transcription, DNA-dependent",PF09174;,1.00E-69,CHOYP_MAF1.1.1,,,,,,,MAF1_BOVIN,Bos taurus (Bovine),"negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; transcription, DNA-templated [GO:0006351]; transcription factor TFIIIB complex assembly [GO:0070217]" comp141155_c0_seq2,1877,36.8673,0.48845945,3,6,,4.00E-84,Q6PGU2,Repressor of RNA polymerase III transcription MAF1 homolog,Repressor of RNA polymerase III transcription MAF1 homolog,GO:0005737; GO:0016480; GO:0005634; GO:0006351,"cytoplasm; negative regulation of transcription from RNA polymerase III promoter; nucleus; transcription, DNA-dependent",PF09174;,1.00E-69,CHOYP_MAF1.1.1,,,,,,,MAF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; transcription, DNA-templated [GO:0006351]; transcription factor TFIIIB complex assembly [GO:0070217]" comp141159_c0_seq1,2328,38.9175,0.41978048,2665,3891,,4.00E-23,Q4PIN7,FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 4 (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005528; GO:0000412; GO:0005730; GO:0003755; GO:0006457,FK506 binding; histone peptidyl-prolyl isomerization; nucleolus; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,3.00E-20,CHOYP_LOC100880757.2.2,,,,,,,FKBP4_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),chaperone-mediated protein folding [GO:0061077]; histone peptidyl-prolyl isomerization [GO:0000412] comp141159_c0_seq2,796,39.196,0.61059896,19,10,,5.00E-14,Q4R4J7,Nucleolin,Nucleolin,GO:0003723; GO:0005737; GO:0005730; GO:0000166; GO:0030529; GO:0042162,RNA binding; cytoplasm; nucleolus; nucleotide binding; ribonucleoprotein complex; telomeric DNA binding,PF00076;,,,,,,,,,NUCL_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp141159_c0_seq4,1413,38.2166,0.37412114,53,27,,1.00E-24,Q26486,46 kDa FK506-binding nuclear protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),46 kDa FK506-binding nuclear protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0003677; GO:0005528; GO:0000412; GO:0005730; GO:0003755; GO:0006457,DNA binding; FK506 binding; histone peptidyl-prolyl isomerization; nucleolus; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,2.00E-20,CHOYP_LOC100880757.2.2,,,,,,,FKBP4_SPOFR,Spodoptera frugiperda (Fall armyworm),histone peptidyl-prolyl isomerization [GO:0000412]; protein folding [GO:0006457] comp141162_c0_seq1,448,45.9821,0.34015321,36056,82148,,6.00E-54,P04646,60S ribosomal protein L35a,60S ribosomal protein L35a,GO:0005840; GO:0003735; GO:0000049; GO:0006412,ribosome; structural constituent of ribosome; tRNA binding; translation,PF01247;,1.00E-60,CHOYP_BRAFLDRAFT_67316.1.1,2.00E-82,ruditapes2_lrc5113,,,,,RL35A_RAT,Rattus norvegicus (Rat),cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273] comp141162_c3_seq1,2759,40.8481,0.50805829,4070,24853,,0,Q6B855,Transketolase (TK) (EC 2.2.1.1),Transketolase (TK) (EC 2.2.1.1),GO:0046872; GO:0040008; GO:0004802,metal ion binding; regulation of growth; transketolase activity,PF02779;PF02780;PF00456;,5.00E-152,CHOYP_BRAFLDRAFT_82353.1.1,,,,,,,TKT_BOVIN,Bos taurus (Bovine),metabolic process [GO:0008152]; regulation of growth [GO:0040008] comp141163_c0_seq1,1926,42.0561,0.30581895,45,331,,2.00E-114,P83436,Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7),Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7),GO:0000139; GO:0017119; GO:0006886; GO:0006486; GO:0034067; GO:0050821; GO:0006890,"Golgi membrane; Golgi transport complex; intracellular protein transport; protein glycosylation; protein localization to Golgi apparatus; protein stabilization; retrograde vesicle-mediated transport, Golgi to ER",PF10191;,5.00E-112,CHOYP_LOC581128.1.1,,,,,,,COG7_HUMAN,Homo sapiens (Human),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp141164_c1_seq1,2699,39.3479,0.56732561,15,23,,2.00E-45,P0A9W5,Uncharacterized ABC transporter ATP-binding protein YjjK,Energy-dependent translational throttle protein EttA (Translational regulatory factor EttA),GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;PF12848;,,,,,,,,,YJJK_SHIFL,Shigella flexneri,regulation of translation [GO:0006417]; translation [GO:0006412] comp141164_c1_seq2,2627,40.0837,0.55299363,23,72,,3.00E-99,P63389,Uncharacterized ABC transporter ATP-binding protein YheS,Uncharacterized ABC transporter ATP-binding protein YheS,GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;PF12848;,,,,,,,,,YHES_ECOLI,Escherichia coli (strain K12),transport [GO:0006810] comp141164_c1_seq3,2227,41.7602,0.59867357,0,10,,0,Q9UG63,ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2),ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2),GO:0005524; GO:0006200; GO:0043190; GO:0016887; GO:0005740; GO:0005215,ATP binding; ATP catabolic process; ATP-binding cassette (ABC) transporter complex; ATPase activity; mitochondrial envelope; transporter activity,PF00005;PF12848;,0,CHOYP_ABCF2.1.2,,,,,,,ABCF2_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp141165_c0_seq2,654,38.5321,0.6188601,0,0,,2.00E-07,P61584,"Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) (Fragment)","Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) (Fragment)",GO:0005524; GO:0000139; GO:0006915; GO:0032059; GO:0005814; GO:0005856; GO:0035556; GO:0030027; GO:0046872; GO:0005543; GO:0005886; GO:0004674; GO:0001726,ATP binding; Golgi membrane; apoptotic process; bleb; centriole; cytoskeleton; intracellular signal transduction; lamellipodium; metal ion binding; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; ruffle,PF08912;,,,,,,,,,ROCK1_PANTR,Pan troglodytes (Chimpanzee),apoptotic process [GO:0006915]; myoblast migration [GO:0051451]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of establishment of cell polarity [GO:2000114]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266] comp141165_c0_seq3,845,41.0651,0.73516146,8,29,,2.00E-31,O14578,Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21),GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0048699; GO:0035556; GO:0046872; GO:0007091; GO:0007067; GO:0000070; GO:0050774; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; generation of neurons; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitosis; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,,,,,,,,,CTRO_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467] comp141165_c0_seq4,709,39.3512,0.66389742,8,10,,,,,,,,,2.00E-11,CHOYP_CIT.2.2,,,,,,,,, comp141165_c0_seq9,790,40.7595,0.70186448,0,0,,7.00E-21,O54874,Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0004674; GO:0051056; GO:0005083,ATP binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; protein serine/threonine kinase activity; regulation of small GTPase mediated signal transduction; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;,,,,,,,,,MRCKA_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056] comp141166_c0_seq2,1679,47.0518,0.3354785,11,0,,1.00E-165,A2AN08,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),GO:0005737; GO:0005856; GO:0016021; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp141166_c0_seq5,940,47.5532,0.45716651,44,12,,9.00E-97,Q9VLT5,Protein purity of essence (Interaction calmodulin and colossal molecular mass protein) (Protein Calossin) (Protein pushover),Protein purity of essence (Interaction calmodulin and colossal molecular mass protein) (Protein Calossin) (Protein pushover),GO:0005516; GO:0042066; GO:0016567; GO:0050896; GO:0007291; GO:0004842; GO:0007601; GO:0008270,calmodulin binding; perineurial glial growth; protein ubiquitination; response to stimulus; sperm individualization; ubiquitin-protein ligase activity; visual perception; zinc ion binding,PF13764;PF02207;,3.00E-168,CHOYP_UBR4.1.1,,,,,,,POE_DROME,Drosophila melanogaster (Fruit fly),glial cell growth [GO:0042065]; perineurial glial growth [GO:0042066]; response to stimulus [GO:0050896]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]; visual perception [GO:0007601] comp141166_c0_seq8,1679,47.0518,0.33513525,2,0,,3.00E-159,Q2TL32,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_RAT,Rattus norvegicus (Rat),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp141166_c2_seq3,522,49.4253,0.47373362,36,4,,,,,,,,,4.00E-68,CHOYP_UBR4.1.1,,,,,,,,, comp141169_c0_seq2,1390,34.3165,0.98474441,9,54,,6.00E-07,P04630,Calmodulin-like protein,Calmodulin-like protein,GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALL_CAEEL,Caenorhabditis elegans, comp141171_c0_seq1,1830,40.2186,0.71892778,176,332,,3.00E-64,O01479,Tropomodulin (Tmod-like protein) (cTmd1) (Uncoordinated protein 94),Tropomodulin (Tmod-like protein) (cTmd1) (Uncoordinated protein 94),GO:0051015; GO:0007015; GO:0051694; GO:0045214; GO:0005865,actin filament binding; actin filament organization; pointed-end actin filament capping; sarcomere organization; striated muscle thin filament,PF03250;,6.00E-92,CHOYP_LOC100372150.1.1,,,,,,,TMOD_CAEEL,Caenorhabditis elegans,embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament depolymerization [GO:0030835]; nematode larval development [GO:0002119]; pointed-end actin filament capping [GO:0051694]; sarcomere organization [GO:0045214] comp141174_c0_seq2,2089,45.3327,0.44793323,0,0,,6.00E-158,Q8ND04,Protein SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog),Protein SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog),GO:0005829; GO:0010467; GO:0000184; GO:0045859,"cytosol; gene expression; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of protein kinase activity",PF10220;,,,,,,,,,SMG8_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859]" comp141174_c0_seq3,2868,44.212,0.4139848,23,20,,0,Q0VA04,Protein smg8 (Protein smg-8 homolog),Protein smg8 (Protein smg-8 homolog),GO:0000184; GO:0045859,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of protein kinase activity",PF10220;,,,,,,,,,SMG8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859]" comp141174_c0_seq4,1411,44.3657,0.30269513,11,0,,2.00E-64,B0W730,Protein SMG8 (Protein smg-8 homolog),Protein SMG8 (Protein smg-8 homolog),GO:0000184,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",PF10220;,2.00E-64,CHOYP_SMG8.1.1,,,,,,,SMG8_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp141174_c0_seq6,1577,43.6271,0.49342942,3,0,,,,,,,,,8.00E-96,CHOYP_SMG8.1.1,,,,,,,,, comp141176_c0_seq2,1682,39.8335,0.45150921,17,61,,,,,,,,,3.00E-63,CHOYP_LOC100889523.1.1,,,,,,,,, comp141177_c0_seq1,3697,40.1677,0.54044578,0,0,,7.00E-107,Q14BN4,Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein),Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein),GO:0005887; GO:0005815; GO:0006936; GO:0042383; GO:0005790,integral to plasma membrane; microtubule organizing center; muscle contraction; sarcolemma; smooth endoplasmic reticulum,PF00498;,5.00E-116,CHOYP_SLMAP.5.8,,,,,,,SLMAP_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936] comp141177_c0_seq2,1855,38.3827,0.67784573,0,7,,,,,,,,,7.00E-28,CHOYP_BRAFLDRAFT_106105.1.1,,,,,,,,, comp141177_c0_seq3,3878,40.9232,0.57020424,0,0,,1.00E-18,Q8C0G2,TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3),TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3),GO:0016021,integral to membrane,,1.00E-135,CHOYP_SLMAP.8.8,,,,,,,T3JAM_MOUSE,Mus musculus (Mouse), comp141177_c0_seq4,3941,40.8272,0.56352791,0,0,,9.00E-145,Q14BN4,Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein),Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein),GO:0005887; GO:0005815; GO:0006936; GO:0042383; GO:0005790,integral to plasma membrane; microtubule organizing center; muscle contraction; sarcolemma; smooth endoplasmic reticulum,PF00498;,,,,,,,,,SLMAP_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936] comp141177_c0_seq5,2351,39.1748,0.66880261,0,0,,,,,,,,,9.00E-28,CHOYP_BRAFLDRAFT_106105.1.1,,,,,,,,, comp141177_c0_seq7,3760,40.0798,0.53349413,0,0,,9.00E-107,Q14BN4,Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein),Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein),GO:0005887; GO:0005815; GO:0006936; GO:0042383; GO:0005790,integral to plasma membrane; microtubule organizing center; muscle contraction; sarcolemma; smooth endoplasmic reticulum,PF00498;,5.00E-116,CHOYP_SLMAP.5.8,,,,,,,SLMAP_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936] comp141182_c0_seq1,2487,39.6864,0.59737882,308,438,,8.00E-88,A0JPP8,Coiled-coil domain-containing protein 61,Coiled-coil domain-containing protein 61,,,,7.00E-80,CHOYP_LOC100373421.1.1,,,,,,,CCD61_RAT,Rattus norvegicus (Rat), comp141184_c0_seq1,1841,44.3237,0.64900545,19,6,,7.00E-06,Q96JS3,PiggyBac transposable element-derived protein 1 (Cerebral protein 4),PiggyBac transposable element-derived protein 1 (Cerebral protein 4),GO:0016020; GO:0005634; GO:0005044; GO:0003700,membrane; nucleus; scavenger receptor activity; sequence-specific DNA binding transcription factor activity,PF13843;PF02023;,,,3.00E-36,ruditapes_c8206,,,,,PGBD1_HUMAN,Homo sapiens (Human), comp141184_c0_seq2,1855,44.3127,0.64465689,37,10,,8.00E-35,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp141185_c0_seq1,3714,39.4992,0.50627461,5299,600,,0,Q8IYE0,Coiled-coil domain-containing protein 146,Coiled-coil domain-containing protein 146,,,,0,CHOYP_CCDC146.1.1,,,,,,,CC146_HUMAN,Homo sapiens (Human), comp141188_c0_seq1,4013,36.8801,0.51477004,56,502,,3.00E-130,O95628,CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp),CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp),GO:0003723; GO:0005829; GO:0000289; GO:0000166; GO:0005634; GO:0051865; GO:0004842; GO:0008270,RNA binding; cytosol; nuclear-transcribed mRNA poly(A) tail shortening; nucleotide binding; nucleus; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00076;,,,,,,,,,CNOT4_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; protein autoubiquitination [GO:0051865]" comp141188_c0_seq3,3374,38.3225,0.5362147,27,146,,1.00E-134,O95628,CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp),CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp),GO:0003723; GO:0005829; GO:0000289; GO:0000166; GO:0005634; GO:0051865; GO:0004842; GO:0008270,RNA binding; cytosol; nuclear-transcribed mRNA poly(A) tail shortening; nucleotide binding; nucleus; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00076;,1.00E-179,CHOYP_LOC100367166.1.1,,,,,,,CNOT4_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; protein autoubiquitination [GO:0051865]" comp141188_c1_seq1,291,37.8007,0.59169898,2,73,,1.00E-20,Q3KQ71,Sodium channel modifier 1,Sodium channel modifier 1,GO:0008380; GO:0006397; GO:0046872; GO:0016607,RNA splicing; mRNA processing; metal ion binding; nuclear speck,PF15805;PF15803;,,,,,,,,,SCNM1_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp141190_c0_seq1,3182,35.9208,0.44532435,234,127,,1.00E-31,Q8NB50,Zinc finger protein 62 homolog (Zfp-62),Zinc finger protein 62 homolog (Zfp-62),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZFP62_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq1,1293,45.1663,0.45722793,0,0,,3.00E-40,Q6ZN57,Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751),Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,2.00E-45,CHOYP_BRAFLDRAFT_98113.1.1,,,,,,,ZFP2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq10,3100,36.9355,0.44659726,0,0,,9.00E-36,Q9UK13,Zinc finger protein 221,Zinc finger protein 221,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN221_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq11,3235,39.4127,0.43016665,0,0,,7.00E-114,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq12,1158,39.2055,0.54007496,0,0,,5.00E-31,Q8N988,Zinc finger protein 557,Zinc finger protein 557,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13465;,,,,,,,,,ZN557_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq2,535,37.757,0.58003154,0,0,,8.00E-08,Q0VCJ6,Zinc finger and BTB domain-containing protein 8A,Zinc finger and BTB domain-containing protein 8A,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT8A_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq3,3177,36.9846,0.44339808,0,0,,9.00E-36,Q9UK13,Zinc finger protein 221,Zinc finger protein 221,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN221_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq4,3312,39.4022,0.4280704,0,0,,4.00E-44,Q80W31,Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74),Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN569_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq5,1304,45.1687,0.4831994,0,0,,9.00E-140,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,2.00E-45,CHOYP_BRAFLDRAFT_98113.1.1,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq6,546,37.9121,0.61391901,0,0,,7.00E-12,O57415,Ras-responsive element-binding protein 1 (RREB-1),Ras-responsive element-binding protein 1 (RREB-1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,RREB1_CHICK,Gallus gallus (Chicken),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]" comp141190_c2_seq7,1169,39.2643,0.5557882,0,0,,6.00E-33,Q3KQV3,Zinc finger protein 792,Zinc finger protein 792,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN792_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141190_c2_seq9,499,39.0782,0.79821521,3,27,,4.00E-13,Q8BID6,Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4),Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4),GO:0046872; GO:2001199; GO:0030853; GO:0045650; GO:0045656; GO:0003676; GO:0005634; GO:2001200; GO:0006355; GO:0006351,"metal ion binding; negative regulation of dendritic cell differentiation; negative regulation of granulocyte differentiation; negative regulation of macrophage differentiation; negative regulation of monocyte differentiation; nucleic acid binding; nucleus; positive regulation of dendritic cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT46_MOUSE,Mus musculus (Mouse),"negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141192_c1_seq4,634,40.694,0.34813683,1,38,,2.00E-20,P01041,Cystatin-B (Cystatin-beta) (Liver thiol proteinase inhibitor) (Stefin-B),Cystatin-B (Cystatin-beta) (Liver thiol proteinase inhibitor) (Stefin-B),GO:0008344; GO:0004869; GO:0005737; GO:0005730; GO:0042981,adult locomotory behavior; cysteine-type endopeptidase inhibitor activity; cytoplasm; nucleolus; regulation of apoptotic process,PF00031;,,,,,,,,,CYTB_RAT,Rattus norvegicus (Rat),adult locomotory behavior [GO:0008344] comp141193_c0_seq2,764,36.2565,0.08052645,28,32,,,,,,,,,,,1.00E-11,ruditapes_c25617,,,,,,, comp141195_c1_seq2,1277,30.6969,0.36781812,292,1479,,,,,,,,,,,3.00E-22,ruditapes_c29520,,,,,,, comp141196_c0_seq1,371,40.1617,0.63844857,5,8,,3.00E-10,A4IHY6,Low-density lipoprotein receptor class A domain-containing protein 3,Low-density lipoprotein receptor class A domain-containing protein 3,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00057;,,,,,,,,,LRAD3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141196_c0_seq3,742,39.8922,0.51926666,26,70,,3.00E-08,Q95209,Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA),Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA),GO:0005794; GO:0008203; GO:0006897; GO:0005768; GO:0005615; GO:0016021; GO:0006869; GO:0034362; GO:0016020; GO:0006605; GO:0014910,Golgi apparatus; cholesterol metabolic process; endocytosis; endosome; extracellular space; integral to membrane; lipid transport; low-density lipoprotein particle; membrane; protein targeting; regulation of smooth muscle cell migration,PF00041;PF00057;PF00058;PF15902;PF15901;,,,,,,,,,SORL_RABIT,Oryctolagus cuniculus (Rabbit),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; protein targeting [GO:0006605]; regulation of smooth muscle cell migration [GO:0014910] comp141197_c0_seq1,2373,42.0986,0.34636715,100,7,,,,,,,,,5.00E-120,CHOYP_BRAFLDRAFT_125356.2.3,,,,,,,,, comp141197_c0_seq2,2433,42.3346,0.33391262,40,0,,2.00E-63,Q3V0L5,Leucine-rich repeat-containing protein 43,Leucine-rich repeat-containing protein 43,,,,2.00E-117,CHOYP_BRAFLDRAFT_125356.2.3,,,,,,,LRC43_MOUSE,Mus musculus (Mouse), comp141197_c0_seq5,729,38.2716,0.35456084,8,7,,,,,,,,,7.00E-17,CHOYP_contig_052469,,,,,,,,, comp141197_c0_seq7,1933,43.4558,0.3755255,4,0,,2.00E-64,Q3V0L5,Leucine-rich repeat-containing protein 43,Leucine-rich repeat-containing protein 43,,,,,,,,,,,,LRC43_MOUSE,Mus musculus (Mouse), comp141199_c0_seq1,854,39.4614,0.54940815,1461,10,male>female,,,,,,,,2.00E-24,CHOYP_contig_055406,,,,,,,,, comp141203_c0_seq10,583,39.4511,0.44645036,23,15,,,,,,,,,1.00E-44,CHOYP_BRAFLDRAFT_104092.10.11,,,,,,,,, comp141203_c0_seq4,499,45.0902,0.59354464,23,10,,2.00E-75,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,1.00E-81,CHOYP_LOC100123553.1.1,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141203_c0_seq8,208,47.1154,0.35053221,1,0,,1.00E-32,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,,,,,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141203_c0_seq9,282,45.0355,0.43294782,12,18,,1.00E-32,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,,,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141210_c1_seq2,1197,39.6825,0.40824334,30,225,,4.00E-45,Q8BJM3,R3H and coiled-coil domain-containing protein 1-like (Growth inhibition and differentiation-related protein 88 homolog),Coiled-coil domain-containing protein R3HCC1L (Growth inhibition and differentiation-related protein 88 homolog) (R3H and coiled-coil domain-containing protein 1-like),GO:0000166,nucleotide binding,,8.00E-25,CHOYP_LOC100378849.1.1,,,,,,,R3HCL_MOUSE,Mus musculus (Mouse), comp141211_c1_seq1,1800,41.4444,0.35490804,143,656,,2.00E-130,Q5ZMW3,Apoptosis inhibitor 5 (API-5),Apoptosis inhibitor 5 (API-5),GO:0006915; GO:0005737; GO:0017134; GO:0043066; GO:0005681,apoptotic process; cytoplasm; fibroblast growth factor binding; negative regulation of apoptotic process; spliceosomal complex,PF05918;,6.00E-60,CHOYP_API5.1.1,,,,,,,API5_CHICK,Gallus gallus (Chicken),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of fibroblast apoptotic process [GO:2000270] comp141212_c0_seq1,2057,39.7667,0.93206544,1,281,female>male,2.00E-07,Q9FPW6,BTB/POZ domain-containing protein POB1 (POZ/BTB CONTAINING-PROTEIN 1) (AtPOB1),BTB/POZ domain-containing protein POB1 (POZ/BTB CONTAINING-PROTEIN 1) (AtPOB1),GO:0005634; GO:0016567; GO:0010114,nucleus; protein ubiquitination; response to red light,PF07707;PF00651;,,,,,,,,,POB1_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ubiquitination [GO:0016567]; response to red light [GO:0010114] comp141212_c0_seq4,2210,39.4118,0.97602935,0,234,female,8.00E-45,Q0V9W6,BTB/POZ domain-containing protein 6,BTB/POZ domain-containing protein 6,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141213_c0_seq2,2272,37.2799,0.55281625,217,888,,5.00E-44,Q99P31,Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-interacting protein 1),Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-interacting protein 1),GO:0032436; GO:0031398,positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination,PF08609;,5.00E-31,CHOYP_BRAFLDRAFT_125073.1.1,,,,,,,HPBP1_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398] comp141214_c0_seq1,2020,36.2376,0.53320532,213,4023,,6.00E-110,O77460,Inorganic pyrophosphatase (EC 3.6.1.1) (Nucleosome-remodeling factor 38 kDa subunit) (Pyrophosphate phospho-hydrolase) (PPase),Inorganic pyrophosphatase (EC 3.6.1.1) (Nucleosome-remodeling factor 38 kDa subunit) (Pyrophosphate phospho-hydrolase) (PPase),GO:0016589; GO:0005737; GO:0035076; GO:0004427; GO:0000287; GO:0042766; GO:0006796; GO:0045747; GO:0035206; GO:0006355; GO:0006351,"NURF complex; cytoplasm; ecdysone receptor-mediated signaling pathway; inorganic diphosphatase activity; magnesium ion binding; nucleosome mobilization; phosphate-containing compound metabolic process; positive regulation of Notch signaling pathway; regulation of hemocyte proliferation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00719;,1.00E-100,CHOYP_LOC100367353.1.1,,,,,,,IPYR_DROME,Drosophila melanogaster (Fruit fly),"chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; nucleosome mobilization [GO:0042766]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of hemocyte proliferation [GO:0035206]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141215_c0_seq1,1284,37.0717,0.58197499,8,37,,7.00E-09,Q63ZK1,Mitochondrial intermembrane space import and assembly protein 40-B (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B),Mitochondrial intermembrane space import and assembly protein 40-B (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B),GO:0051084; GO:0005758; GO:0015035; GO:0045041; GO:0022417,'de novo' posttranslational protein folding; mitochondrial intermembrane space; protein disulfide oxidoreductase activity; protein import into mitochondrial intermembrane space; protein maturation by protein folding,PF06747;,,,,,,,,,MI40B_XENLA,Xenopus laevis (African clawed frog),'de novo' posttranslational protein folding [GO:0051084]; protein import into mitochondrial intermembrane space [GO:0045041]; protein maturation by protein folding [GO:0022417] comp141215_c0_seq2,1227,37.5713,0.52084091,0,0,,,,,,,,,,,7.00E-17,ruditapes_c749,,,,,,, comp141218_c0_seq1,910,34.3956,0.71283341,7,71,,4.00E-15,Q5ZHQ2,Galectin-related protein (Lectin galactoside-binding-like protein),Galectin-related protein (Lectin galactoside-binding-like protein),GO:0030246; GO:0005622,carbohydrate binding; intracellular,PF00337;,,,2.00E-17,ruditapes_c29835,,,,,LEGL_CHICK,Gallus gallus (Chicken), comp141218_c0_seq2,1198,37.3122,0.55306685,2,181,,8.00E-26,P47967,Galectin-5 (Gal-5) (RL-18),Galectin-5 (Gal-5) (RL-18),GO:0030246,carbohydrate binding,PF00337;,,,,,,,,,LEG5_RAT,Rattus norvegicus (Rat), comp141218_c0_seq3,1672,41.0287,0.63996113,49,626,,8.00E-59,P38552,Galectin-4 (Gal-4) (L-36 lactose-binding protein) (L36LBP) (Lactose-binding lectin 4),Galectin-4 (Gal-4) (L-36 lactose-binding protein) (L36LBP) (Lactose-binding lectin 4),GO:0030246,carbohydrate binding,PF00337;,,,9.00E-68,ruditapes2_c73,,,,,LEG4_RAT,Rattus norvegicus (Rat), comp141218_c0_seq4,1258,38.2353,0.69813588,5,138,,7.00E-24,O08573,Galectin-9 (Gal-9),Galectin-9 (Gal-9),GO:0030246; GO:0005737; GO:0005576; GO:0016936; GO:0007157,carbohydrate binding; cytoplasm; extracellular region; galactoside binding; heterophilic cell-cell adhesion,PF00337;,,,2.00E-30,ruditapes2_c438,,,,,LEG9_MOUSE,Mus musculus (Mouse),"cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune system process [GO:0002376]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]" comp141219_c0_seq1,2180,47.6147,0.6263129,303,257,,0,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,0,CHOYP_PHUM_PHUM226120.2.7,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp141220_c0_seq1,1581,29.0955,0.30089787,710,4677,,,,,,,,,,,1.00E-20,ruditapes_c11963,,,,,,, comp141221_c0_seq1,1863,46.2695,0.97084941,30,1030,,1.00E-48,Q19673,Putative tyrosinase-like protein tyr-3,Putative tyrosinase-like protein tyr-3,GO:0046872; GO:0004497,metal ion binding; monooxygenase activity,PF01549;PF00264;,,,,,,,,,TYR3_CAEEL,Caenorhabditis elegans, comp141221_c0_seq2,510,46.8627,0.93511058,0,27,,4.00E-22,Q19673,Putative tyrosinase-like protein tyr-3,Putative tyrosinase-like protein tyr-3,GO:0046872; GO:0004497,metal ion binding; monooxygenase activity,PF01549;PF00264;,,,,,,,,,TYR3_CAEEL,Caenorhabditis elegans, comp141222_c0_seq1,2188,40.7221,0.38519991,463,4289,,0,Q6TGS6,"Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)","Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)",GO:0005524; GO:0005737; GO:0000049; GO:0004831; GO:0006437,ATP binding; cytoplasm; tRNA binding; tyrosine-tRNA ligase activity; tyrosyl-tRNA aminoacylation,PF00579;PF01588;,0,CHOYP_SYYC.2.2,5.00E-161,ruditapes_c15255,,,,,SYYC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; tyrosyl-tRNA aminoacylation [GO:0006437]; valyl-tRNA aminoacylation [GO:0006438] comp141224_c0_seq1,772,37.8238,0.62306301,106,287,,1.00E-15,Q8K2Y7,"39S ribosomal protein L47, mitochondrial (L47mt) (MRP-L47)","39S ribosomal protein L47, mitochondrial (L47mt) (MRP-L47)",GO:0005761; GO:0005739; GO:0003735; GO:0006412,mitochondrial ribosome; mitochondrion; structural constituent of ribosome; translation,PF06984;,,,,,,,,,RM47_MOUSE,Mus musculus (Mouse),mitochondrial translation [GO:0032543] comp141225_c0_seq1,3146,38.9065,0.47189626,513,4590,,0,Q9WUA2,Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS),Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS),GO:0005524; GO:0003723; GO:0005737; GO:0000287; GO:0004826; GO:0006432,ATP binding; RNA binding; cytoplasm; magnesium ion binding; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation,PF03483;PF03484;,2.00E-151,CHOYP_NEMVEDRAFT_V1G188942.1.1,,,,,,,SYFB_MOUSE,Mus musculus (Mouse),phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] comp141226_c0_seq5,528,35.4167,1.04740651,19,34,,,,,,,,,6.00E-22,CHOYP_contig_055724,,,,,,,,, comp141227_c6_seq1,785,37.5796,0.43573941,80,173,,1.00E-10,Q9JJR5,A-kinase-interacting protein 1 (Breast cancer-associated gene 3 protein) (PKA-interacting protein) (Proline-rich protein BCA3),A-kinase-interacting protein 1 (Breast cancer-associated gene 3 protein) (PKA-interacting protein) (Proline-rich protein BCA3),GO:0005634; GO:0034446,nucleus; substrate adhesion-dependent cell spreading,,,,,,,,,,AKIP1_MOUSE,Mus musculus (Mouse),regulation of NIK/NF-kappaB signaling [GO:1901222]; substrate adhesion-dependent cell spreading [GO:0034446] comp141228_c4_seq1,3683,38.7456,0.32338356,102,51,,5.00E-08,Q6ZRK6,Coiled-coil domain-containing protein 73 (Sarcoma antigen NY-SAR-79),Coiled-coil domain-containing protein 73 (Sarcoma antigen NY-SAR-79),,,PF15818;,,,,,,,,,CCD73_HUMAN,Homo sapiens (Human), comp141229_c0_seq1,1737,39.0328,0.36028204,5,1,,4.00E-08,Q9VMJ7,Lysine-specific demethylase lid (EC 1.14.11.-) (Histone demethylase lid) (Jumonji/ARID domain-containing protein lid) (Protein little imaginal disks) (Retinoblastoma-binding protein 2 homolog),Lysine-specific demethylase lid (EC 1.14.11.-) (Histone demethylase lid) (Jumonji/ARID domain-containing protein lid) (Protein little imaginal disks) (Retinoblastoma-binding protein 2 homolog),GO:0003677; GO:0070822; GO:0043992; GO:0034647; GO:0045475; GO:0007275; GO:0016706; GO:0045893; GO:0006351; GO:0008270,"DNA binding; Sin3-type complex; histone acetyltransferase activity (H3-K9 specific); histone demethylase activity (H3-trimethyl-K4 specific); locomotor rhythm; multicellular organismal development; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;,2.00E-35,CHOYP_KDM5A.1.1,,,,,,,KDM5_DROME,Drosophila melanogaster (Fruit fly),"chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; histone demethylation [GO:0016577]; histone H3-K4 demethylation [GO:0034720]; histone H3-K4 demethylation, trimethyl-H3-K4-specific [GO:0034721]; histone H3-K9 acetylation [GO:0043970]; larval somatic muscle development [GO:0007526]; locomotor rhythm [GO:0045475]; male germ-line stem cell population maintenance [GO:0036098]; negative regulation of stem cell differentiation [GO:2000737]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of JAK-STAT cascade [GO:0046425]; transcription, DNA-templated [GO:0006351]" comp141229_c1_seq1,4424,44.6203,0.46746833,0,0,,0,P29375,Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2),Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2),GO:0003677; GO:0003682; GO:0016568; GO:0005737; GO:0007275; GO:0005730; GO:0005634; GO:0016706; GO:0045893; GO:0003700; GO:0006366; GO:0008270,"DNA binding; chromatin binding; chromatin modification; cytoplasm; multicellular organismal development; nucleolus; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; zinc ion binding",PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;,,,,,,,,,KDM5A_HUMAN,Homo sapiens (Human),"circadian regulation of gene expression [GO:0032922]; histone H3-K4 demethylation [GO:0034720]; male gonad development [GO:0008584]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366]" comp141229_c1_seq2,4234,44.6623,0.46883969,0,0,,0,P41229,Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169),Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169),GO:0003677; GO:0032453; GO:0005634; GO:0016706; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone demethylase activity (H3-K4 specific); nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;,0,CHOYP_KDM5A.1.1,,,,,,,KDM5C_HUMAN,Homo sapiens (Human),"histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp141229_c1_seq3,4445,44.5669,0.4663886,0,0,,0,P41230,Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169),Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169),GO:0003677; GO:0032453; GO:0005634; GO:0016706; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone demethylase activity (H3-K4 specific); nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;,,,,,,,,,KDM5C_MOUSE,Mus musculus (Mouse),"histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp141229_c1_seq4,2383,44.0201,0.47199621,0,0,,2.00E-99,Q9US53,Jumonji/ARID domain-containing protein 2,Jumonji/ARID domain-containing protein 2,GO:0003677; GO:0006338; GO:0051864; GO:0034648; GO:0034647; GO:0000122; GO:0000790; GO:0008270,DNA binding; chromatin remodeling; histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-dimethyl-K4 specific); histone demethylase activity (H3-trimethyl-K4 specific); negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; zinc ion binding,PF02373;PF02375;PF02928;,0,CHOYP_KDM5A.1.1,,,,,,,JMJ2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp141229_c1_seq5,2404,43.9268,0.4698915,0,0,,1.00E-34,Q6BDA0,Probable lysine-specific demethylase ELF6 (EC 1.14.11.-) (Early flowering 6) (Jumonji domain-containing protein 11) (Probable lysine-specific histone demethylase ELF6),Probable lysine-specific demethylase ELF6 (EC 1.14.11.-) (Early flowering 6) (Jumonji domain-containing protein 11) (Probable lysine-specific histone demethylase ELF6),GO:0051213; GO:0033169; GO:0046872; GO:0048579; GO:0048577; GO:0003676; GO:0005634; GO:0009741; GO:0003700; GO:0006351; GO:0009826,"dioxygenase activity; histone H3-K9 demethylation; metal ion binding; negative regulation of long-day photoperiodism, flowering; negative regulation of short-day photoperiodism, flowering; nucleic acid binding; nucleus; response to brassinosteroid stimulus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; unidimensional cell growth",PF02373;PF02375;,,,,,,,,,ELF6_ARATH,Arabidopsis thaliana (Mouse-ear cress),"histone H3-K9 demethylation [GO:0033169]; negative regulation of long-day photoperiodism, flowering [GO:0048579]; negative regulation of short-day photoperiodism, flowering [GO:0048577]; regulation of transcription, DNA-templated [GO:0006355]; response to brassinosteroid [GO:0009741]; transcription, DNA-templated [GO:0006351]; unidimensional cell growth [GO:0009826]" comp141229_c1_seq6,4255,44.6063,0.46771069,0,0,,0,P29375,Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2),Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2),GO:0003677; GO:0003682; GO:0016568; GO:0005737; GO:0007275; GO:0005730; GO:0005634; GO:0016706; GO:0045893; GO:0003700; GO:0006366; GO:0008270,"DNA binding; chromatin binding; chromatin modification; cytoplasm; multicellular organismal development; nucleolus; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; zinc ion binding",PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;,,,,,,,,,KDM5A_HUMAN,Homo sapiens (Human),"circadian regulation of gene expression [GO:0032922]; histone H3-K4 demethylation [GO:0034720]; male gonad development [GO:0008584]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366]" comp141230_c0_seq2,3665,45.7026,0.42450333,0,0,,0,P35573,"Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]","Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]",GO:0004134; GO:0004135; GO:0005829; GO:0006006; GO:0005978; GO:0005980; GO:0016234; GO:0043033; GO:0005634; GO:0030247; GO:0051384; GO:0007584; GO:0016529; GO:0044281,"4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity; cytosol; glucose metabolic process; glycogen biosynthetic process; glycogen catabolic process; inclusion body; isoamylase complex; nucleus; polysaccharide binding; response to glucocorticoid stimulus; response to nutrient; sarcoplasmic reticulum; small molecule metabolic process",PF06202;PF14701;PF14702;PF14699;,2.00E-132,CHOYP_GDE.1.1,,,,,,,GDE_HUMAN,Homo sapiens (Human),glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584] comp141230_c0_seq5,1280,42.9688,0.41211269,0,0,,5.00E-110,A8BQB4,"Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]","Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]",GO:0004134; GO:0004135; GO:0005737; GO:0005978; GO:0005980,"4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity; cytoplasm; glycogen biosynthetic process; glycogen catabolic process",PF06202;PF14701;PF14702;PF14699;,,,,,,,,,GDE_HORSE,Equus caballus (Horse),glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980] comp141231_c0_seq1,2042,40.4016,0.45155925,11,0,,3.00E-10,Q8H4D4,tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (EC 2.1.1.282); tRNA wybutosine-synthesizing protein 2 homolog (EC 2.5.1.-)],tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)],GO:0008168; GO:0008033,methyltransferase activity; tRNA processing,PF01344;PF02475;PF02676;,,,,,,,,,TYW23_ORYSJ,Oryza sativa subsp. japonica (Rice),tRNA processing [GO:0008033] comp141231_c0_seq10,629,46.7409,0.40846674,0,0,,5.00E-11,Q9MA55,Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4),Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4),GO:0005737; GO:0005829; GO:0000062; GO:0008289; GO:0006869; GO:0005634; GO:0009723; GO:0009753; GO:0009416; GO:0006810,cytoplasm; cytosol; fatty-acyl-CoA binding; lipid binding; lipid transport; nucleus; response to ethylene stimulus; response to jasmonic acid stimulus; response to light stimulus; transport,PF00887;,,,,,,,,,ACBP4_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to light stimulus [GO:0009416]; transport [GO:0006810] comp141231_c0_seq13,2074,42.8158,0.60416223,0,0,,7.00E-45,Q8BYR1,Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein) (tRNA wybutosine-synthesizing protein 4 homolog) (tRNA yW-synthesizing protein 4 homolog),tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (p21WAF1/CIP1 promoter-interacting protein) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase),GO:0003880; GO:0008033,protein C-terminal carboxyl O-methyltransferase activity; tRNA processing,PF04072;,2.00E-34,CHOYP_LOC587803.1.1,,,,,,,LCMT2_MOUSE,Mus musculus (Mouse),C-terminal protein methylation [GO:0006481]; tRNA methylation [GO:0030488]; wybutosine biosynthetic process [GO:0031591] comp141231_c0_seq14,760,45.9211,0.72791867,0,0,,1.00E-09,Q6XHA6,Probable inactive serine/threonine-protein kinase roco10 (Ras of complex proteins and C-terminal of roc 10),Probable inactive serine/threonine-protein kinase roco10 (Ras of complex proteins and C-terminal of roc 10),GO:0005524; GO:0005096; GO:0005622; GO:0043547; GO:0004672; GO:0007165; GO:0038032,ATP binding; GTPase activator activity; intracellular; positive regulation of GTPase activity; protein kinase activity; signal transduction; termination of G-protein coupled receptor signaling pathway,PF13855;PF07714;PF00615;PF00620;,,,,,,,,,ROC10_DICDI,Dictyostelium discoideum (Slime mold),signal transduction [GO:0007165] comp141231_c0_seq15,1276,41.0658,0.67404701,0,0,,3.00E-07,Q8RWD9,Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5),Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5),GO:0005829; GO:0000062; GO:0008289; GO:0006869; GO:0009416,cytosol; fatty-acyl-CoA binding; lipid binding; lipid transport; response to light stimulus,PF00887;,,,,,,,,,ACBP5_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869]; response to hypoxia [GO:0001666]; response to light stimulus [GO:0009416] comp141231_c0_seq16,1332,38.2883,0.41430349,0,0,,3.00E-11,A8JAM0,Coiled-coil domain-containing protein lobo homolog (Flagellar-associated protein 50) (Fragment),Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein lobo homolog) (Flagellar-associated protein 50) (Fragment),GO:0030154; GO:0001539; GO:0031514; GO:0007283,cell differentiation; ciliary or bacterial-type flagellar motility; motile cilium; spermatogenesis,PF13516;PF13855;,,,,,,,,,CC135_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii), comp141231_c0_seq2,2190,40.7763,0.46709314,0,0,,9.00E-45,Q8BYR1,Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein) (tRNA wybutosine-synthesizing protein 4 homolog) (tRNA yW-synthesizing protein 4 homolog),tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (p21WAF1/CIP1 promoter-interacting protein) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase),GO:0003880; GO:0008033,protein C-terminal carboxyl O-methyltransferase activity; tRNA processing,PF04072;,,,,,,,,,LCMT2_MOUSE,Mus musculus (Mouse),C-terminal protein methylation [GO:0006481]; tRNA methylation [GO:0030488]; wybutosine biosynthetic process [GO:0031591] comp141231_c0_seq5,1216,41.6118,0.68688119,0,0,,6.00E-14,P80197,Actin-fragmin kinase (AFK) (EC 2.7.11.1),Actin-fragmin kinase (AFK) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0004674,ATP binding; cytoplasm; protein serine/threonine kinase activity,PF09192;,,,,,,,,,AFK_PHYPO,Physarum polycephalum (Slime mold), comp141231_c0_seq6,1926,42.5234,0.61536578,0,0,,,,,,,,,1.00E-12,CHOYP_LOC587803.1.1,,,,,,,,, comp141231_c0_seq7,950,40,0.42722419,0,0,,3.00E-14,P80197,Actin-fragmin kinase (AFK) (EC 2.7.11.1),Actin-fragmin kinase (AFK) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0004674,ATP binding; cytoplasm; protein serine/threonine kinase activity,PF09192;,,,,,,,,,AFK_PHYPO,Physarum polycephalum (Slime mold), comp141231_c0_seq8,494,45.3441,0.43462822,0,0,,2.00E-06,Q55A09,Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1),GO:0005524; GO:0016021; GO:0004674,ATP binding; integral to membrane; protein serine/threonine kinase activity,PF07714;,,,,,,,,,Y9963_DICDI,Dictyostelium discoideum (Slime mold), comp141231_c0_seq9,1392,38.0029,0.44476396,0,0,,2.00E-10,Q8H4D4,tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (EC 2.1.1.282); tRNA wybutosine-synthesizing protein 2 homolog (EC 2.5.1.-)],tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)],GO:0008168; GO:0008033,methyltransferase activity; tRNA processing,PF01344;PF02475;PF02676;,,,,,,,,,TYW23_ORYSJ,Oryza sativa subsp. japonica (Rice),tRNA processing [GO:0008033] comp141234_c1_seq3,1565,38.0831,0.56969431,66,61,,3.00E-46,P82649,"28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt)","28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF10245;,,,,,,,,,RT22_BOVIN,Bos taurus (Bovine),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp141234_c1_seq4,949,38.2508,0.44978271,101,282,,2.00E-13,Q6PFL6,Coiled-coil domain-containing protein 43,Coiled-coil domain-containing protein 43,,,,,,,,,,,,CCD43_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141235_c0_seq2,1996,33.3667,0.88630972,0,0,,2.00E-39,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,2.00E-39,ruditapes_c9179,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141235_c0_seq6,1982,33.3502,0.87511055,0,0,,2.00E-29,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,4.00E-44,CHOYP_LOC100892567.8.8,2.00E-19,ruditapes_c30953,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141235_c0_seq8,2054,33.3496,0.88079502,0,0,,2.00E-39,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,4.00E-44,CHOYP_LOC100892567.8.8,2.00E-39,ruditapes_c9179,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141236_c0_seq1,2835,44.1623,0.50692004,0,0,,1.00E-15,Q01484,Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin),Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin),GO:0051117; GO:0031430; GO:0030315; GO:0033292; GO:0030018; GO:0016324; GO:0003283; GO:0007411; GO:0016323; GO:0060048; GO:0006874; GO:0043034; GO:0005856; GO:0005829; GO:0005887; GO:0014704; GO:0044325; GO:0086046; GO:0048471; GO:1901021; GO:0051928; GO:2001259; GO:0010628; GO:1901018; GO:0043268; GO:0045211; GO:0015459; GO:0030674; GO:0036309; GO:0036371; GO:0034394; GO:0070972; GO:0050821; GO:0072661; GO:0086014; GO:0010881; GO:0086091; GO:0086005; GO:0060307; GO:0070296,"ATPase binding; M band; T-tubule; T-tubule organization; Z disc; apical plasma membrane; atrial septum development; axon guidance; basolateral plasma membrane; cardiac muscle contraction; cellular calcium ion homeostasis; costamere; cytoskeleton; cytosol; integral to plasma membrane; intercalated disc; ion channel binding; membrane depolarization involved in regulation of SA node cell action potential; perinuclear region of cytoplasm; positive regulation of calcium ion transmembrane transporter activity; positive regulation of calcium ion transport; positive regulation of cation channel activity; positive regulation of gene expression; positive regulation of potassium ion transmembrane transporter activity; positive regulation of potassium ion transport; postsynaptic membrane; potassium channel regulator activity; protein binding, bridging; protein localization to M-band; protein localization to T-tubule; protein localization to cell surface; protein localization to endoplasmic reticulum; protein stabilization; protein targeting to plasma membrane; regulation of atrial cardiac muscle cell action potential; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of heart rate by cardiac conduction; regulation of ventricular cardiac muscle cell action potential; regulation of ventricular cardiac muscle cell membrane repolarization; sarcoplasmic reticulum calcium ion transport",PF00023;PF12796;PF00531;PF00791;,,,,,,,,,ANK2_HUMAN,Homo sapiens (Human),atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; cellular protein localization [GO:0034613]; ER to Golgi vesicle-mediated transport [GO:0006888]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein targeting to plasma membrane [GO:0072661]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] comp141236_c0_seq3,656,46.3415,0.45833985,54,49,,2.00E-63,Q04861,Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit],Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit],GO:0002755; GO:0051059; GO:0035419; GO:0007250; GO:0005829; GO:0045087; GO:0001818; GO:0050728; GO:0045083; GO:0045892; GO:0005634; GO:0045944; GO:0043565; GO:0003700; GO:0035681; GO:0034134; GO:0035682; GO:0034138; GO:0034142; GO:0034146; GO:0034154; GO:0006351,"MyD88-dependent toll-like receptor signaling pathway; NF-kappaB binding; activation of MAPK activity involved in innate immune response; activation of NF-kappaB-inducing kinase activity; cytosol; innate immune response; negative regulation of cytokine production; negative regulation of inflammatory response; negative regulation of interleukin-12 biosynthetic process; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; toll-like receptor 15 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 21 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 7 signaling pathway; transcription, DNA-dependent",PF00023;PF12796;PF00531;PF16179;PF00554;,1.00E-64,CHOYP_NFKB.1.1,,,,,,,NFKB1_CHICK,Gallus gallus (Chicken),cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994] comp141236_c0_seq4,3027,43.8057,0.51732038,17,15,,3.00E-20,Q63746,NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (RL/IF-1),NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (RL/IF-1),GO:0033256; GO:0051059; GO:0007253; GO:0005829; GO:0031663; GO:0032088; GO:0045746; GO:0010888; GO:0010745; GO:0045638; GO:0008139; GO:0070427; GO:0070431; GO:0005634; GO:0005886; GO:0032270; GO:0010875; GO:0045944; GO:0000060; GO:0042127; GO:0043330; GO:0032495; GO:0034142,"I-kappaB/NF-kappaB complex; NF-kappaB binding; cytoplasmic sequestering of NF-kappaB; cytosol; lipopolysaccharide-mediated signaling pathway; negative regulation of NF-kappaB transcription factor activity; negative regulation of Notch signaling pathway; negative regulation of lipid storage; negative regulation of macrophage derived foam cell differentiation; negative regulation of myeloid cell differentiation; nuclear localization sequence binding; nucleotide-binding oligomerization domain containing 1 signaling pathway; nucleotide-binding oligomerization domain containing 2 signaling pathway; nucleus; plasma membrane; positive regulation of cellular protein metabolic process; positive regulation of cholesterol efflux; positive regulation of transcription from RNA polymerase II promoter; protein import into nucleus, translocation; regulation of cell proliferation; response to exogenous dsRNA; response to muramyl dipeptide; toll-like receptor 4 signaling pathway",PF00023;PF12796;,,,,,,,,,IKBA_RAT,Rattus norvegicus (Rat),"cellular response to cytokine stimulus [GO:0071345]; cellular response to organic cyclic compound [GO:0071407]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; liver regeneration [GO:0097421]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of Notch signaling pathway [GO:0045746]; nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070427]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus, translocation [GO:0000060]; regulation of cell proliferation [GO:0042127]; response to exogenous dsRNA [GO:0043330]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; toll-like receptor 4 signaling pathway [GO:0034142]" comp141236_c0_seq5,2664,44.8574,0.49283272,0,0,,9.00E-45,Q63369,Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] (Fragment),Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] (Fragment),GO:0005829; GO:0003690; GO:0043066; GO:0001818; GO:0050728; GO:0045083; GO:0045892; GO:0005634; GO:0045944; GO:0043234; GO:0009617; GO:0046688; GO:0006979; GO:0003700; GO:0007165; GO:0000976; GO:0006351,"cytosol; double-stranded DNA binding; negative regulation of apoptotic process; negative regulation of cytokine production; negative regulation of inflammatory response; negative regulation of interleukin-12 biosynthetic process; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein complex; response to bacterium; response to copper ion; response to oxidative stress; sequence-specific DNA binding transcription factor activity; signal transduction; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF12796;PF00531;,,,,,,,,,NFKB1_RAT,Rattus norvegicus (Rat),"cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; response to bacterium [GO:0009617]; response to copper ion [GO:0046688]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; transcription, DNA-templated [GO:0006351]" comp141236_c1_seq2,453,43.7086,0.90079804,2,5,,2.00E-34,P19838,Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit],Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit],GO:0038095; GO:0033256; GO:0002755; GO:0050852; GO:0035666; GO:0006915; GO:0071347; GO:0071260; GO:0005829; GO:0003690; GO:0006954; GO:0045087; GO:0031293; GO:0005739; GO:0043066; GO:0010956; GO:0032269; GO:0032375; GO:0001818; GO:0050728; GO:0045083; GO:0000122; GO:0010957; GO:0048011; GO:0005654; GO:0051092; GO:0090263; GO:1900127; GO:0010884; GO:0010744; GO:0045944; GO:0045893; GO:0032481; GO:0009617; GO:0046688; GO:0006979; GO:0003700; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124; GO:0008134; GO:0006366; GO:0000976,"Fc-epsilon receptor signaling pathway; I-kappaB/NF-kappaB complex; MyD88-dependent toll-like receptor signaling pathway; T cell receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; apoptotic process; cellular response to interleukin-1; cellular response to mechanical stimulus; cytosol; double-stranded DNA binding; inflammatory response; innate immune response; membrane protein intracellular domain proteolysis; mitochondrion; negative regulation of apoptotic process; negative regulation of calcidiol 1-monooxygenase activity; negative regulation of cellular protein metabolic process; negative regulation of cholesterol transport; negative regulation of cytokine production; negative regulation of inflammatory response; negative regulation of interleukin-12 biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of vitamin D biosynthetic process; neurotrophin TRK receptor signaling pathway; nucleoplasm; positive regulation of NF-kappaB transcription factor activity; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of hyaluronan biosynthetic process; positive regulation of lipid storage; positive regulation of macrophage derived foam cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of type I interferon production; response to bacterium; response to copper ion; response to oxidative stress; sequence-specific DNA binding transcription factor activity; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway; transcription factor binding; transcription from RNA polymerase II promoter; transcription regulatory region sequence-specific DNA binding",PF12796;PF00531;PF16179;PF00554;,5.00E-29,CHOYP_NFKB.1.1,,,,,,,NFKB1_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to copper ion [GO:0046688]; response to muscle stretch [GO:0035994]; response to oxidative stress [GO:0006979]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription from RNA polymerase II promoter [GO:0006366]" comp141238_c1_seq2,2154,27.8552,0.65218136,32,8,,,,,,,,,,,5.00E-15,ruditapes_c18101,,,,,,, comp141239_c1_seq2,2286,37.4016,0.3068941,51,331,,1.00E-63,Q9WUQ2,Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12),Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12),GO:0003677; GO:0005783; GO:0016021; GO:0005634; GO:0015031; GO:0003700; GO:0006351; GO:0016192,"DNA binding; endoplasmic reticulum; integral to membrane; nucleus; protein transport; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; vesicle-mediated transport",PF00400;,2.00E-42,CHOYP_ZGC_92203.1.1,,,,,,,PREB_MOUSE,Mus musculus (Mouse),"COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein exit from endoplasmic reticulum [GO:0032527]; transcription, DNA-templated [GO:0006351]" comp141240_c0_seq1,1516,36.7414,0.47402567,0,0,,,,,,,,,2.00E-22,CHOYP_ISCW_ISCW017809.1.2,,,,,,,,, comp141240_c0_seq2,4472,41.7039,0.51710985,0,0,,5.00E-137,Q96PY5,Formin-like protein 2 (Formin homology 2 domain-containing protein 2),Formin-like protein 2 (Formin homology 2 domain-containing protein 2),GO:0030866; GO:0005737; GO:0022604,cortical actin cytoskeleton organization; cytoplasm; regulation of cell morphogenesis,PF06367;PF06371;PF02181;,0,CHOYP_ISCW_ISCW017809.2.2,,,,,,,FMNL2_HUMAN,Homo sapiens (Human),cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] comp141240_c0_seq4,2468,44.0438,0.51180557,0,0,,4.00E-16,Q8S0F0,Formin-like protein 1 (OsFH1),Formin-like protein 1 (OsFH1),GO:0005884; GO:0045010; GO:0016021,actin filament; actin nucleation; integral to membrane,PF02181;,,,,,,,,,FH1_ORYSJ,Oryza sativa subsp. japonica (Rice), comp141240_c0_seq5,4445,41.5973,0.51757861,3,0,,7.00E-142,Q96PY5,Formin-like protein 2 (Formin homology 2 domain-containing protein 2),Formin-like protein 2 (Formin homology 2 domain-containing protein 2),GO:0030866; GO:0005737; GO:0022604,cortical actin cytoskeleton organization; cytoplasm; regulation of cell morphogenesis,PF06367;PF06371;PF02181;,0,CHOYP_ISCW_ISCW017809.2.2,,,5.00E-71,FP010851.p.cg.6,1,,FMNL2_HUMAN,Homo sapiens (Human),cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] comp141240_c0_seq6,2495,44.1683,0.50377202,0,0,,,,,,,,,,,1.00E-17,ruditapes_c23479,,,,,,, comp141240_c0_seq7,4402,41.5947,0.52828733,4,0,,6.00E-135,Q9VUC6,Formin-like protein CG32138,Formin-like protein CG32138,GO:0003779; GO:0030036; GO:0048812,actin binding; actin cytoskeleton organization; neuron projection morphogenesis,PF06367;PF06371;PF02181;,0,CHOYP_ISCW_ISCW017809.2.2,,,,,,,Y2138_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; mushroom body development [GO:0016319]; neuron projection morphogenesis [GO:0048812]; ommatidial rotation [GO:0016318] comp141240_c0_seq8,4435,41.6685,0.5227483,0,0,,4.00E-137,Q96PY5,Formin-like protein 2 (Formin homology 2 domain-containing protein 2),Formin-like protein 2 (Formin homology 2 domain-containing protein 2),GO:0030866; GO:0005737; GO:0022604,cortical actin cytoskeleton organization; cytoplasm; regulation of cell morphogenesis,PF06367;PF06371;PF02181;,,,,,,,,,FMNL2_HUMAN,Homo sapiens (Human),cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] comp141240_c0_seq9,1553,36.9607,0.45571866,0,0,,,,,,,,,2.00E-22,CHOYP_ISCW_ISCW017809.1.2,,,,,,,,, comp141244_c0_seq2,905,39.558,0.42847737,16,153,,9.00E-36,Q5PPZ5,Bridging integrator 3 homolog,Bridging integrator 3 homolog,GO:0000917; GO:0005737; GO:0005856,barrier septum assembly; cytoplasm; cytoskeleton,PF03114;,,,,,,,,,BIN3_XENLA,Xenopus laevis (African clawed frog),barrier septum assembly [GO:0000917] comp141244_c0_seq3,1389,36.7891,0.45239004,31,130,,3.00E-13,P25343,Reduced viability upon starvation protein 161,Reduced viability upon starvation protein 161,GO:0030479; GO:0051666; GO:0031532; GO:0000747; GO:0008092; GO:0006897; GO:0060988; GO:0005937; GO:0045121; GO:0006970; GO:0042594,actin cortical patch; actin cortical patch localization; actin cytoskeleton reorganization; conjugation with cellular fusion; cytoskeletal protein binding; endocytosis; lipid tube assembly; mating projection; membrane raft; response to osmotic stress; response to starvation,PF03114;,,,,,,,,,RV161_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin cortical patch localization [GO:0051666]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; conjugation with cellular fusion [GO:0000747]; endocytosis [GO:0006897]; lipid tube assembly [GO:0060988]; membrane tubulation [GO:0097320]; response to osmotic stress [GO:0006970]; response to starvation [GO:0042594] comp141245_c1_seq1,886,36.0045,0.41889073,19,98,,8.00E-81,B6NXD5,BRCA1-A complex subunit BRE (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein),BRCA1-A complex subunit BRE (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein),GO:0070531; GO:0070552; GO:0031572; GO:0006915; GO:0016568; GO:0005737; GO:0006302; GO:0031593; GO:0045739; GO:0010212,BRCA1-A complex; BRISC complex; G2 DNA damage checkpoint; apoptotic process; chromatin modification; cytoplasm; double-strand break repair; polyubiquitin binding; positive regulation of DNA repair; response to ionizing radiation,PF06113;,1.00E-20,CHOYP_BRE.1.1,,,,,,,BRE_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),apoptotic process [GO:0006915]; cell division [GO:0051301]; chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212] comp141249_c0_seq1,2251,41.8036,0.39820826,489,4195,,1.00E-138,Q8BTS4,Nuclear pore complex protein Nup54 (54 kDa nucleoporin) (Nucleoporin Nup54),Nuclear pore complex protein Nup54 (54 kDa nucleoporin) (Nucleoporin Nup54),GO:0051028; GO:0031965; GO:0005643; GO:0005487; GO:0006605,mRNA transport; nuclear membrane; nuclear pore; nucleocytoplasmic transporter activity; protein targeting,PF13874;,8.00E-85,CHOYP_NUP54.1.1,,,,,,,NUP54_MOUSE,Mus musculus (Mouse),mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]; protein heterotetramerization [GO:0051290]; protein heterotrimerization [GO:0070208]; protein homooligomerization [GO:0051260]; protein targeting to nuclear inner membrane [GO:0036228]; regulation of protein import into nucleus [GO:0042306] comp141255_c0_seq1,984,45.4268,0.65571358,0,0,,5.00E-91,Q2XWK0,Synaptic vesicle 2-related protein (SV2-related protein),Synaptic vesicle 2-related protein (SV2-related protein),GO:0030054; GO:0016021; GO:0030672; GO:0022857,cell junction; integral to membrane; synaptic vesicle membrane; transmembrane transporter activity,PF07690;PF00083;,,,,,,,,,SVOP_XENLA,Xenopus laevis (African clawed frog), comp141255_c0_seq3,1035,45.4106,0.6197863,0,0,,3.00E-76,Q6PDF3,Putative transporter SVOPL (SVOP-like protein),Putative transporter SVOPL (SVOP-like protein),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,SVOPL_MOUSE,Mus musculus (Mouse), comp141255_c0_seq5,983,45.2696,0.65834145,0,0,,3.00E-79,Q2XWK0,Synaptic vesicle 2-related protein (SV2-related protein),Synaptic vesicle 2-related protein (SV2-related protein),GO:0030054; GO:0016021; GO:0030672; GO:0022857,cell junction; integral to membrane; synaptic vesicle membrane; transmembrane transporter activity,PF07690;PF00083;,8.00E-43,CHOYP_SVOP.2.2,,,,,,,SVOP_XENLA,Xenopus laevis (African clawed frog), comp141255_c0_seq6,1034,45.2611,0.62381341,0,0,,6.00E-09,E8ZB61,Gallate transporter (Gallate permease),Gallate transporter (Gallate permease),GO:0008643; GO:0016021; GO:0055085; GO:0005215,carbohydrate transport; integral to membrane; transmembrane transport; transporter activity,PF07690;,,,,,,,,,GALT_PSEPU,Pseudomonas putida (Arthrobacter siderocapsulatus),carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085] comp141260_c1_seq1,629,41.8124,0.83941818,18,53,,1.00E-14,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141261_c0_seq1,1470,43.6735,0.97234654,1,825,female>male,2.00E-12,Q9NZR2,Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),GO:0005509; GO:0016021; GO:0005041; GO:0015031; GO:0006898,calcium ion binding; integral to membrane; low-density lipoprotein receptor activity; protein transport; receptor-mediated endocytosis,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1B_HUMAN,Homo sapiens (Human),protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp141263_c3_seq1,2410,38.2158,0.50030192,102,255,,1.00E-41,P54726,UV excision repair protein RAD23 homolog A (HR23A) (mHR23A),UV excision repair protein RAD23 homolog A (HR23A) (mHR23A),GO:0003684; GO:0006289; GO:0005634; GO:0043161; GO:0000502; GO:0006974,damaged DNA binding; nucleotide-excision repair; nucleus; proteasomal ubiquitin-dependent protein catabolic process; proteasome complex; response to DNA damage stimulus,PF00627;PF00240;PF09280;,2.00E-36,CHOYP_RD23B.1.1,,,,,,,RD23A_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] comp141263_c3_seq2,2928,36.3388,0.50714319,48,808,,3.00E-41,P54726,UV excision repair protein RAD23 homolog A (HR23A) (mHR23A),UV excision repair protein RAD23 homolog A (HR23A) (mHR23A),GO:0003684; GO:0006289; GO:0005634; GO:0043161; GO:0000502; GO:0006974,damaged DNA binding; nucleotide-excision repair; nucleus; proteasomal ubiquitin-dependent protein catabolic process; proteasome complex; response to DNA damage stimulus,PF00627;PF00240;PF09280;,,,,,,,,,RD23A_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] comp141264_c0_seq2,1276,38.0094,0.43445745,94,269,,3.00E-40,Q9CXC3,Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-),Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-),GO:0043504; GO:0005739; GO:0008297,mitochondrial DNA repair; mitochondrion; single-stranded DNA exodeoxyribonuclease activity,,,,,,,,,,CT072_MOUSE,Mus musculus (Mouse),mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] comp141265_c0_seq1,3045,41.9704,0.86857433,0,0,,,,,,,,,6.00E-19,CHOYP_MYPT1.2.2,,,,,,,,, comp141265_c0_seq10,4023,42.5553,0.78168544,0,0,,1.00E-87,O60237,Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2),Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2),GO:0000086; GO:0015629; GO:0005737; GO:0008047; GO:0005654; GO:0005886; GO:0006937; GO:0007165,G2/M transition of mitotic cell cycle; actin cytoskeleton; cytoplasm; enzyme activator activity; nucleoplasm; plasma membrane; regulation of muscle contraction; signal transduction,PF12796;PF15898;,9.00E-113,CHOYP_LOC100114433.4.4,,,,,,,MYPT2_HUMAN,Homo sapiens (Human),G2/M transition of mitotic cell cycle [GO:0000086]; regulation of muscle contraction [GO:0006937]; signal transduction [GO:0007165] comp141265_c0_seq11,1213,43.446,0.63626878,0,0,,1.00E-97,Q9DBR7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),GO:0071889; GO:0072357; GO:0005813; GO:0051297; GO:0043292; GO:0004857; GO:0000776; GO:0007067; GO:0019208; GO:0045944; GO:0006470; GO:0030155; GO:0035507; GO:0046822,14-3-3 protein binding; PTW/PP1 phosphatase complex; centrosome; centrosome organization; contractile fiber; enzyme inhibitor activity; kinetochore; mitosis; phosphatase regulator activity; positive regulation of transcription from RNA polymerase II promoter; protein dephosphorylation; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity; regulation of nucleocytoplasmic transport,PF12796;PF15898;,1.00E-117,CHOYP_LOC100114433.3.4,,,,,,,MYPT1_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] comp141265_c0_seq13,3978,42.6094,0.78822415,0,0,,1.00E-87,O60237,Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2),Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2),GO:0000086; GO:0015629; GO:0005737; GO:0008047; GO:0005654; GO:0005886; GO:0006937; GO:0007165,G2/M transition of mitotic cell cycle; actin cytoskeleton; cytoplasm; enzyme activator activity; nucleoplasm; plasma membrane; regulation of muscle contraction; signal transduction,PF12796;PF15898;,7.00E-19,CHOYP_MYPT1.2.2,,,,,,,MYPT2_HUMAN,Homo sapiens (Human),G2/M transition of mitotic cell cycle [GO:0000086]; regulation of muscle contraction [GO:0006937]; signal transduction [GO:0007165] comp141265_c0_seq15,3900,42.8974,0.79235854,0,0,,4.00E-90,Q9DBR7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),GO:0071889; GO:0072357; GO:0005813; GO:0051297; GO:0043292; GO:0004857; GO:0000776; GO:0007067; GO:0019208; GO:0045944; GO:0006470; GO:0030155; GO:0035507; GO:0046822,14-3-3 protein binding; PTW/PP1 phosphatase complex; centrosome; centrosome organization; contractile fiber; enzyme inhibitor activity; kinetochore; mitosis; phosphatase regulator activity; positive regulation of transcription from RNA polymerase II promoter; protein dephosphorylation; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity; regulation of nucleocytoplasmic transport,PF12796;PF15898;,4.00E-117,CHOYP_LOC100114433.3.4,,,,,,,MYPT1_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] comp141265_c0_seq16,2785,41.8671,0.85429897,0,0,,,,,,,,,5.00E-19,CHOYP_MYPT1.2.2,,,,,,,,, comp141265_c0_seq19,3987,42.7138,0.79294221,0,0,,4.00E-90,Q9DBR7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),GO:0071889; GO:0072357; GO:0005813; GO:0051297; GO:0043292; GO:0004857; GO:0000776; GO:0007067; GO:0019208; GO:0045944; GO:0006470; GO:0030155; GO:0035507; GO:0046822,14-3-3 protein binding; PTW/PP1 phosphatase complex; centrosome; centrosome organization; contractile fiber; enzyme inhibitor activity; kinetochore; mitosis; phosphatase regulator activity; positive regulation of transcription from RNA polymerase II promoter; protein dephosphorylation; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity; regulation of nucleocytoplasmic transport,PF12796;PF15898;,4.00E-117,CHOYP_LOC100114433.3.4,,,,,,,MYPT1_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] comp141265_c0_seq2,4110,42.3844,0.78235363,0,0,,5.00E-90,Q9DBR7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),GO:0071889; GO:0072357; GO:0005813; GO:0051297; GO:0043292; GO:0004857; GO:0000776; GO:0007067; GO:0019208; GO:0045944; GO:0006470; GO:0030155; GO:0035507; GO:0046822,14-3-3 protein binding; PTW/PP1 phosphatase complex; centrosome; centrosome organization; contractile fiber; enzyme inhibitor activity; kinetochore; mitosis; phosphatase regulator activity; positive regulation of transcription from RNA polymerase II promoter; protein dephosphorylation; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity; regulation of nucleocytoplasmic transport,PF12796;PF15898;,9.00E-113,CHOYP_LOC100114433.4.4,,,,,,,MYPT1_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] comp141265_c0_seq20,3132,41.7625,0.86775509,0,0,,,,,,,,,1.00E-14,CHOYP_MYPT1.2.2,,,,,,,,, comp141265_c0_seq21,4065,42.4354,0.78881839,0,0,,5.00E-90,Q9DBR7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1),GO:0071889; GO:0072357; GO:0005813; GO:0051297; GO:0043292; GO:0004857; GO:0000776; GO:0007067; GO:0019208; GO:0045944; GO:0006470; GO:0030155; GO:0035507; GO:0046822,14-3-3 protein binding; PTW/PP1 phosphatase complex; centrosome; centrosome organization; contractile fiber; enzyme inhibitor activity; kinetochore; mitosis; phosphatase regulator activity; positive regulation of transcription from RNA polymerase II promoter; protein dephosphorylation; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity; regulation of nucleocytoplasmic transport,PF12796;PF15898;,4.00E-117,CHOYP_LOC100114433.3.4,,,,,,,MYPT1_MOUSE,Mus musculus (Mouse),cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] comp141265_c0_seq23,1155,37.8355,0.99044756,0,0,,7.00E-14,Q6DRG7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit),GO:0071889; GO:0072357; GO:0051017; GO:0005737; GO:0001889; GO:0019208; GO:0030155; GO:0035507,14-3-3 protein binding; PTW/PP1 phosphatase complex; actin filament bundle assembly; cytoplasm; liver development; phosphatase regulator activity; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity,PF12796;PF15898;,2.00E-19,CHOYP_MYPT1.2.2,8.00E-54,ruditapes2_c2168,,,,,MYPT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament bundle assembly [GO:0051017]; actin filament bundle distribution [GO:0070650]; convergent extension involved in axis elongation [GO:0060028]; liver development [GO:0001889]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of myosin-light-chain-phosphatase activity [GO:0035507] comp141265_c0_seq4,3168,41.572,0.85218593,0,0,,1.00E-13,Q6DRG7,Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit),Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit),GO:0071889; GO:0072357; GO:0051017; GO:0005737; GO:0001889; GO:0019208; GO:0030155; GO:0035507,14-3-3 protein binding; PTW/PP1 phosphatase complex; actin filament bundle assembly; cytoplasm; liver development; phosphatase regulator activity; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity,PF12796;PF15898;,6.00E-19,CHOYP_MYPT1.2.2,,,,,,,MYPT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament bundle assembly [GO:0051017]; actin filament bundle distribution [GO:0070650]; convergent extension involved in axis elongation [GO:0060028]; liver development [GO:0001889]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of myosin-light-chain-phosphatase activity [GO:0035507] comp141265_c0_seq5,2827,41.705,0.8643631,0,0,,,,,,,,,,,3.00E-26,ruditapes_c21556,,,,,,, comp141265_c0_seq8,1242,37.6006,0.97888761,0,0,,,,,,,,,5.00E-15,CHOYP_MYPT1.2.2,5.00E-25,ruditapes_c19393,,,,,,, comp141265_c0_seq9,1404,43.3761,0.65912374,0,0,,2.00E-19,Q12955,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0043001; GO:0030315; GO:0007411; GO:0043194; GO:0007409; GO:0016323; GO:0045296; GO:0009986; GO:0043034; GO:0014704; GO:0044325; GO:0016328; GO:0005764; GO:0072660; GO:0071709; GO:0000281; GO:0033268; GO:0033270; GO:0010628; GO:1900827; GO:0045838; GO:2000651; GO:0010765; GO:0045211; GO:0030674; GO:0072661; GO:0019228; GO:0043266; GO:0007165; GO:0030507; GO:0014731; GO:0005200; GO:0050808,"Golgi to plasma membrane protein transport; T-tubule; axon guidance; axon initial segment; axonogenesis; basolateral plasma membrane; cadherin binding; cell surface; costamere; intercalated disc; ion channel binding; lateral plasma membrane; lysosome; maintenance of protein location in plasma membrane; membrane assembly; mitotic cytokinesis; node of Ranvier; paranode region of axon; positive regulation of gene expression; positive regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential; positive regulation of membrane potential; positive regulation of sodium ion transmembrane transporter activity; positive regulation of sodium ion transport; postsynaptic membrane; protein binding, bridging; protein targeting to plasma membrane; regulation of action potential in neuron; regulation of potassium ion transport; signal transduction; spectrin binding; spectrin-associated cytoskeleton; structural constituent of cytoskeleton; synapse organization",PF00023;PF12796;PF13606;PF00531;PF00791;,1.00E-117,CHOYP_LOC100114433.3.4,,,,,,,ANK3_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] comp141266_c0_seq1,1521,41.2229,0.47457718,418,3185,,2.00E-164,Q91WM3,U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K),U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K),GO:0003723; GO:0005730; GO:0006364; GO:0030529,RNA binding; nucleolus; rRNA processing; ribonucleoprotein complex,PF00400;,1.00E-81,CHOYP_LOC100376387.1.1,2.00E-57,ruditapes_c11750,,,,,U3IP2_MOUSE,Mus musculus (Mouse),rRNA processing [GO:0006364] comp141267_c2_seq2,1892,37.1564,0.49688314,0,0,,2.00E-90,Q9CX34,Suppressor of G2 allele of SKP1 homolog,Protein SGT1 homolog (Suppressor of G2 allele of SKP1 homolog),GO:0005737; GO:0005634,cytoplasm; nucleus,PF04969;PF05002;,,,,,,,,,SUGT1_MOUSE,Mus musculus (Mouse),positive regulation by host of symbiont catalytic activity [GO:0043947]; regulation of protein stability [GO:0031647] comp141267_c2_seq4,1894,37.3284,0.46129516,32,38,,2.00E-57,Q9SUR9,Protein SGT1 homolog A (AtSGT1a) (Suppressor of G2 allele of SKP1 homolog A),Protein SGT1 homolog A (AtSGT1a) (Suppressor of G2 allele of SKP1 homolog A),GO:0019005; GO:0071365; GO:0006952; GO:0045087; GO:0005634; GO:2000072; GO:0006511,"SCF ubiquitin ligase complex; cellular response to auxin stimulus; defense response; innate immune response; nucleus; regulation of defense response to fungus, incompatible interaction; ubiquitin-dependent protein catabolic process",PF04969;PF05002;PF13181;,8.00E-34,CHOYP_LOC100210536.1.1,,,,,,,SGT1A_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; innate immune response [GO:0045087]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp141267_c2_seq7,2032,36.9094,0.46849739,0,0,,6.00E-90,Q9CX34,Suppressor of G2 allele of SKP1 homolog,Protein SGT1 homolog (Suppressor of G2 allele of SKP1 homolog),GO:0005737; GO:0005634,cytoplasm; nucleus,PF04969;PF05002;,,,,,,,,,SUGT1_MOUSE,Mus musculus (Mouse),positive regulation by host of symbiont catalytic activity [GO:0043947]; regulation of protein stability [GO:0031647] comp141267_c2_seq8,2030,36.6995,0.47371655,0,0,,3.00E-71,Q0JL44,Protein SGT1 homolog (OsSGT1) (Suppressor of G2 allele of SKP1 homolog),Protein SGT1 homolog (OsSGT1) (Suppressor of G2 allele of SKP1 homolog),GO:0005737; GO:0042742; GO:0050832; GO:0005634,cytoplasm; defense response to bacterium; defense response to fungus; nucleus,PF04969;PF05002;PF00515;,8.00E-34,CHOYP_LOC100210536.1.1,,,,,,,SGT1_ORYSJ,Oryza sativa subsp. japonica (Rice),defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832] comp141269_c1_seq4,746,36.4611,0.64791139,131,678,,9.00E-19,Q6DGQ1,NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1),NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1),GO:0005525; GO:0003924; GO:0005737; GO:0016020; GO:0007264,GTP binding; GTPase activity; cytoplasm; membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,KBRS1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),small GTPase mediated signal transduction [GO:0007264] comp141270_c1_seq10,2737,43.1129,0.4566759,0,0,,2.00E-138,Q8NBS3,Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11),Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11),GO:0016323; GO:0015106; GO:0046715; GO:0030003; GO:0042044; GO:0015252; GO:0005452; GO:0016021; GO:0046983; GO:0005272; GO:0015293,basolateral plasma membrane; bicarbonate transmembrane transporter activity; borate transmembrane transporter activity; cellular cation homeostasis; fluid transport; hydrogen ion channel activity; inorganic anion exchanger activity; integral to membrane; protein dimerization activity; sodium channel activity; symporter activity,PF00955;,,,,,,,,,S4A11_HUMAN,Homo sapiens (Human),bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; fluid transport [GO:0042044]; proton transport [GO:0015992]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814] comp141270_c1_seq5,2531,43.1845,0.45781106,0,0,,2.00E-40,Q5DTL9,Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10),Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10),GO:0015301; GO:0016323; GO:0005452; GO:0005887; GO:0006486; GO:0006885; GO:0006814; GO:0015293,anion:anion antiporter activity; basolateral plasma membrane; inorganic anion exchanger activity; integral to plasma membrane; protein glycosylation; regulation of pH; sodium ion transport; symporter activity,PF07565;PF00955;,9.00E-47,CHOYP_LOC579418.1.2,,,,,,,S4A10_MOUSE,Mus musculus (Mouse),bicarbonate transport [GO:0015701]; brain morphogenesis [GO:0048854]; hydrogen ion transmembrane transport [GO:1902600]; locomotory exploration behavior [GO:0035641]; multicellular organism growth [GO:0035264]; post-embryonic development [GO:0009791]; protein glycosylation [GO:0006486]; pyramidal neuron development [GO:0021860]; regulation of cellular pH [GO:0030641]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; response to light stimulus [GO:0009416]; sodium ion transport [GO:0006814] comp141270_c1_seq7,2661,42.8035,0.50087299,0,0,,1.00E-46,P02730,Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233),Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233),GO:0030018; GO:0016323; GO:0015701; GO:0006873; GO:0015108; GO:0030863; GO:0005452; GO:0005887; GO:0043495; GO:0044281,Z disc; basolateral plasma membrane; bicarbonate transport; cellular ion homeostasis; chloride transmembrane transporter activity; cortical cytoskeleton; inorganic anion exchanger activity; integral to plasma membrane; protein anchor; small molecule metabolic process,PF07565;PF00955;,0,CHOYP_LOC579418.2.2,,,,,,,B3AT_HUMAN,Homo sapiens (Human),anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; cellular ion homeostasis [GO:0006873]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; regulation of intracellular pH [GO:0051453] comp141270_c1_seq8,2455,42.8513,0.50741603,0,0,,6.00E-143,Q8NBS3,Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11),Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11),GO:0016323; GO:0015106; GO:0046715; GO:0030003; GO:0042044; GO:0015252; GO:0005452; GO:0016021; GO:0046983; GO:0005272; GO:0015293,basolateral plasma membrane; bicarbonate transmembrane transporter activity; borate transmembrane transporter activity; cellular cation homeostasis; fluid transport; hydrogen ion channel activity; inorganic anion exchanger activity; integral to membrane; protein dimerization activity; sodium channel activity; symporter activity,PF00955;,0,CHOYP_LOC579418.2.2,,,,,,,S4A11_HUMAN,Homo sapiens (Human),bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; fluid transport [GO:0042044]; proton transport [GO:0015992]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814] comp141271_c0_seq1,3877,43.4872,0.56141879,29,45,,8.00E-118,O88923,Latrophilin-2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2),Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2),GO:0004930; GO:0007420; GO:0030246; GO:0016021; GO:0043005; GO:0007218; GO:0005886,G-protein coupled receptor activity; brain development; carbohydrate binding; integral to membrane; neuron projection; neuropeptide signaling pathway; plasma membrane,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,1.00E-28,CHOYP_LOC657847.1.1,,,,,,,LPHN2_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166] comp141271_c0_seq2,3806,43.3001,0.53785984,9,58,,4.00E-128,O88917,Latrophilin-1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1),Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1),GO:0004930; GO:0030424; GO:0007420; GO:0035584; GO:0030246; GO:0050839; GO:0030054; GO:0030426; GO:0007157; GO:0016021; GO:0016524; GO:0007218; GO:0090129; GO:0014069; GO:0042734; GO:0016079; GO:0015643,G-protein coupled receptor activity; axon; brain development; calcium-mediated signaling using intracellular calcium source; carbohydrate binding; cell adhesion molecule binding; cell junction; growth cone; heterophilic cell-cell adhesion; integral to membrane; latrotoxin receptor activity; neuropeptide signaling pathway; positive regulation of synapse maturation; postsynaptic density; presynaptic membrane; synaptic vesicle exocytosis; toxic substance binding,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,,,,,,,,,LPHN1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse maturation [GO:0090129]; synaptic vesicle exocytosis [GO:0016079] comp141271_c0_seq3,634,42.9022,0.99218997,12,10,,4.00E-20,B3N8M1,Latrophilin Cirl,Latrophilin Cirl,GO:0004930; GO:0030246; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF16489;PF02140;PF01825;,,,,,,,,,LPHN_DROER,Drosophila erecta (Fruit fly),cell surface receptor signaling pathway [GO:0007166] comp141272_c1_seq1,1529,42.2498,0.45852333,48,344,,7.00E-137,Q63707,"Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)","Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)",GO:0044205; GO:0006207; GO:0010181; GO:0004158; GO:0008144; GO:0007565; GO:0016021; GO:0007595; GO:0005743; GO:0043025; GO:0043065; GO:0090140; GO:0031000; GO:0042493; GO:0042594; GO:0048039,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; FMN binding; dihydroorotate oxidase activity; drug binding; female pregnancy; integral to membrane; lactation; mitochondrial inner membrane; neuronal cell body; positive regulation of apoptotic process; regulation of mitochondrial fission; response to caffeine; response to drug; response to starvation; ubiquinone binding,PF01180;,2.00E-53,CHOYP_PYRD.1.1,1.00E-34,ruditapes_c2540,,,,,PYRD_RAT,Rattus norvegicus (Rat),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to L-arginine [GO:1903576]; response to organic cyclic compound [GO:0014070]; response to starvation [GO:0042594] comp141279_c0_seq1,1395,37.9928,0.87647196,0,0,,1.00E-66,Q8BLJ3,PI-PLC X domain-containing protein 3,PI-PLC X domain-containing protein 3,GO:0016042; GO:0008081; GO:0004871,lipid catabolic process; phosphoric diester hydrolase activity; signal transducer activity,,,,,,,,,,PLCX3_MOUSE,Mus musculus (Mouse),lipid catabolic process [GO:0016042] comp141279_c0_seq2,1538,38.6216,0.90989544,9,46,,7.00E-75,Q8BLJ3,PI-PLC X domain-containing protein 3,PI-PLC X domain-containing protein 3,GO:0016042; GO:0008081; GO:0004871,lipid catabolic process; phosphoric diester hydrolase activity; signal transducer activity,,,,,,,,,,PLCX3_MOUSE,Mus musculus (Mouse),lipid catabolic process [GO:0016042] comp141280_c0_seq1,2094,36.9628,0.55990231,26,40,,2.00E-64,P0CO06,Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48),Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48),GO:0006281; GO:0006348; GO:0005737; GO:0004402; GO:0000123,DNA repair; chromatin silencing at telomere; cytoplasm; histone acetyltransferase activity; histone acetyltransferase complex,PF00583;PF10394;,,,,,,,,,HAT1_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),chromatin silencing at telomere [GO:0006348]; DNA repair [GO:0006281] comp141280_c0_seq2,2049,36.7984,0.51954281,6,39,,1.00E-135,O14929,Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1),Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1),GO:0006323; GO:0006348; GO:0005737; GO:0004402; GO:0016363; GO:0005654; GO:0005634; GO:0007584,DNA packaging; chromatin silencing at telomere; cytoplasm; histone acetyltransferase activity; nuclear matrix; nucleoplasm; nucleus; response to nutrient,PF10394;,2.00E-110,CHOYP_LOC100901947.1.1,,,,,,,HAT1_HUMAN,Homo sapiens (Human),chromatin silencing at telomere [GO:0006348]; DNA packaging [GO:0006323]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone H4 acetylation [GO:0043967]; internal protein amino acid acetylation [GO:0006475]; response to nutrient [GO:0007584] comp141281_c0_seq1,2780,40.8633,0.62941383,3897,26,male>female,1.00E-174,Q8N7U6,EF-hand domain-containing family member B,EF-hand domain-containing family member B,GO:0005509,calcium ion binding,PF13499;,2.00E-151,CHOYP_LOC578680.1.1,,,,,,,EFHB_HUMAN,Homo sapiens (Human), comp141282_c0_seq10,5264,45.8397,0.50801201,115,94,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,7.00E-14,CHOYP_DNAH6.3.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp141282_c0_seq11,1220,45.6557,0.56228821,0,0,,2.00E-86,Q0VDD8,"Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14)","Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14)",GO:0005524; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF03028;PF12777;,1.00E-173,CHOYP_LOC100370750.2.2,,,,,,,DYH14_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp141282_c0_seq12,1849,47.7015,0.62887269,0,0,,8.00E-107,Q9P2D7,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018; GO:0009612,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement; response to mechanical stimulus,PF07728;PF12780;PF08393;PF03028;PF12777;,,,,,,,,,DYH1_HUMAN,Homo sapiens (Human),cilium movement involved in cell motility [GO:0060294]; cilium or flagellum-dependent cell motility [GO:0001539]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; response to mechanical stimulus [GO:0009612]; sperm motility [GO:0030317] comp141282_c0_seq15,3484,46.9862,0.58390933,0,0,,6.00E-77,Q9SMH3,"Dynein-1-alpha heavy chain, flagellar inner arm I1 complex (1-alpha DHC) (Dynein-1, subspecies f)","Dynein-1-alpha heavy chain, flagellar inner arm I1 complex (1-alpha DHC) (Dynein-1, subspecies f)",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,7.00E-12,CHOYP_LOC100378331.1.1,,,,,,,DYH1A_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159] comp141282_c0_seq16,3342,47.2172,0.58607905,2,0,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,,,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp141282_c0_seq18,677,43.4269,0.72164533,3,0,,,,,,,,,1.00E-12,CHOYP_LOC100378331.1.1,,,,,,,,, comp141282_c0_seq5,2446,47.1382,0.61460096,0,0,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_LOC100370750.2.2,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp141282_c0_seq6,3685,47.0556,0.56483726,0,0,,3.00E-140,Q923J6,"Dynein heavy chain 12, axonemal (Bm259)","Dynein heavy chain 12, axonemal (Bm259)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;,0,CHOYP_LOC100370750.2.2,,,,,,,DYH12_RAT,Rattus norvegicus (Rat),microtubule-based movement [GO:0007018] comp141283_c4_seq1,655,37.8626,0.77297902,5,16,,9.00E-06,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141283_c4_seq4,501,35.5289,0.70147637,21,17,,8.00E-08,P03934,Transposable element Tc1 transposase,Transposable element Tc1 transposase,GO:0003677; GO:0015074; GO:0004519; GO:0090305; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TC1A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141286_c0_seq1,1171,41.076,0.46798645,163,3904,,,,,,,,,2.00E-19,CHOYP_LOC101069816.1.1,,,,,,,,, comp141287_c1_seq5,591,35.533,0.26887169,10,20,,2.00E-15,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141288_c4_seq2,1479,41.5145,0.58374579,0,11,,0,P36872,Protein phosphatase PP2A 55 kDa regulatory subunit (PR55) (Protein phosphatase PP2A regulatory subunit B) (Protein twins),Protein phosphatase PP2A 55 kDa regulatory subunit (PR55) (Protein phosphatase PP2A regulatory subunit B) (Protein twins),GO:0016055; GO:0051297; GO:0005737; GO:0001700; GO:0007447; GO:0045201; GO:0005875; GO:0000278; GO:0007406; GO:0005634; GO:0006470; GO:0000159; GO:0008601; GO:0004722; GO:0030071; GO:0007423,Wnt receptor signaling pathway; centrosome organization; cytoplasm; embryonic development via the syncytial blastoderm; imaginal disc pattern formation; maintenance of neuroblast polarity; microtubule associated complex; mitotic cell cycle; negative regulation of neuroblast proliferation; nucleus; protein dephosphorylation; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity; regulation of mitotic metaphase/anaphase transition; sensory organ development,,,,,,,,,,2ABA_DROME,Drosophila melanogaster (Fruit fly),centriole replication [GO:0007099]; centrosome organization [GO:0051297]; embryonic development via the syncytial blastoderm [GO:0001700]; imaginal disc pattern formation [GO:0007447]; maintenance of neuroblast polarity [GO:0045201]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle [GO:0000278]; negative regulation of neuroblast proliferation [GO:0007406]; protein dephosphorylation [GO:0006470]; protein stabilization [GO:0050821]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; sensory organ development [GO:0007423]; Wnt signaling pathway [GO:0016055] comp141288_c4_seq3,1460,39.863,0.58967264,10,16,,0,P36876,Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform BRA) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha),Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform BRA) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha),GO:0000159; GO:0008601; GO:0043278; GO:0007165,protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; response to morphine; signal transduction,,0,CHOYP_LOC100567969.1.1,2.00E-145,ruditapes_c12497,,,,,2ABA_RAT,Rattus norvegicus (Rat),response to morphine [GO:0043278] comp141289_c0_seq3,1387,34.1745,0.37630153,0,0,,7.00E-38,P62311,U6 snRNA-associated Sm-like protein LSm3,U6 snRNA-associated Sm-like protein LSm3,GO:0003723; GO:0008380; GO:0071013; GO:0006397,RNA binding; RNA splicing; catalytic step 2 spliceosome; mRNA processing,PF01423;,8.00E-64,CHOYP_LSM3.1.1,,,,,,,LSM3_MOUSE,Mus musculus (Mouse),"cytoplasmic mRNA processing body assembly [GO:0033962]; mRNA splicing, via spliceosome [GO:0000398]" comp141289_c0_seq6,1467,34.6285,0.41357957,24,48,,9.00E-38,P62311,U6 snRNA-associated Sm-like protein LSm3,U6 snRNA-associated Sm-like protein LSm3,GO:0003723; GO:0008380; GO:0071013; GO:0006397,RNA binding; RNA splicing; catalytic step 2 spliceosome; mRNA processing,PF01423;,3.00E-56,CHOYP_LOC100370083.1.1,,,3.00E-62,CU998781.p.cg.6,9,,LSM3_MOUSE,Mus musculus (Mouse),"cytoplasmic mRNA processing body assembly [GO:0033962]; mRNA splicing, via spliceosome [GO:0000398]" comp141290_c0_seq1,3105,45.4106,0.53593091,0,5,,,,,,,,,2.00E-51,CHOYP_RNC.1.1,,,,,,,,, comp141290_c0_seq3,4634,44.1303,0.50399709,214,1124,,0,Q5HZJ0,Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III),Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III),GO:0003723; GO:0004521; GO:0046872; GO:0010586; GO:0005730; GO:0031054; GO:0016075; GO:0004525; GO:0042254,RNA binding; endoribonuclease activity; metal ion binding; miRNA metabolic process; nucleolus; pre-miRNA processing; rRNA catabolic process; ribonuclease III activity; ribosome biogenesis,PF00035;PF14622;PF00636;,5.00E-85,CHOYP_RNC.1.1,,,,,,,RNC_MOUSE,Mus musculus (Mouse),defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; miRNA metabolic process [GO:0010586]; positive regulation of gene expression [GO:0010628]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of regulatory T cell differentiation [GO:0045589]; ribosome biogenesis [GO:0042254]; rRNA catabolic process [GO:0016075] comp141292_c0_seq1,3244,41.2762,0.3783629,211,944,,8.00E-84,Q1HFZ0,tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2),tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2),GO:0051301; GO:0005737; GO:0007067; GO:0005730; GO:0005819; GO:0016428; GO:0000049,cell division; cytoplasm; mitosis; nucleolus; spindle; tRNA (cytosine-5-)-methyltransferase activity; tRNA binding,PF01189;,,,,,,,,,NSUN2_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; meiotic cell cycle checkpoint [GO:0033313]; mitotic nuclear division [GO:0007067]; spermatid development [GO:0007286]; tRNA methylation [GO:0030488] comp141292_c0_seq2,3238,41.1983,0.38047352,42,92,,3.00E-60,Q9W4M9,tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog),tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog),GO:0005737; GO:0005730; GO:0007614; GO:0016428; GO:0000049,cytoplasm; nucleolus; short-term memory; tRNA (cytosine-5-)-methyltransferase activity; tRNA binding,PF01189;,,,,,,,,,NSUN2_DROME,Drosophila melanogaster (Fruit fly),RNA methylation [GO:0001510]; short-term memory [GO:0007614]; tRNA methylation [GO:0030488] comp141293_c0_seq1,2197,40.0546,0.49399612,8,120,,8.00E-127,Q05B18,Protein SHQ1 homolog,Protein SHQ1 homolog,GO:0005829; GO:0005654; GO:0022618,cytosol; nucleoplasm; ribonucleoprotein complex assembly,PF04925;,,,,,,,,,SHQ1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ribonucleoprotein complex assembly [GO:0022618] comp141293_c0_seq2,2178,40.4959,0.48785673,28,111,,3.00E-127,Q05B18,Protein SHQ1 homolog,Protein SHQ1 homolog,GO:0005829; GO:0005654; GO:0022618,cytosol; nucleoplasm; ribonucleoprotein complex assembly,PF04925;,1.00E-13,CHOYP_SHQ1.1.1,,,,,,,SHQ1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ribonucleoprotein complex assembly [GO:0022618] comp141294_c0_seq1,1683,37.4926,0.35957308,6,174,,3.00E-134,A7RF00,Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein),Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein),GO:0019509; GO:0046523; GO:0005737; GO:0005634,L-methionine salvage from methylthioadenosine; S-methyl-5-thioribose-1-phosphate isomerase activity; cytoplasm; nucleus,PF01008;,,,,,,,,,MTNA_NEMVE,Nematostella vectensis (Starlet sea anemone),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp141294_c0_seq3,1357,36.2564,0.34439635,2,9,,3.00E-57,A6RHT9,Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein),Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein),GO:0019509; GO:0046523; GO:0005737; GO:0005634,L-methionine salvage from methylthioadenosine; S-methyl-5-thioribose-1-phosphate isomerase activity; cytoplasm; nucleus,PF01008;,7.00E-45,CHOYP_MTNA.1.1,2.00E-63,ruditapes_c7603,,,,,MTNA_BOTFB,Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp141295_c0_seq1,2077,38.3727,0.34646667,4,8,,,,,,,,,5.00E-30,CHOYP_BRAFLDRAFT_284846.1.2,,,,,,,,, comp141295_c0_seq2,1169,43.7981,0.48704939,0,0,,3.00E-122,Q5R660,Translocation protein SEC63 homolog,Translocation protein SEC63 homolog,GO:0005789; GO:0016021; GO:0001889; GO:0010259; GO:0006807; GO:0031204; GO:0008565; GO:0072001,"endoplasmic reticulum membrane; integral to membrane; liver development; multicellular organismal aging; nitrogen compound metabolic process; posttranslational protein targeting to membrane, translocation; protein transporter activity; renal system development",PF00226;PF02889;,2.00E-108,CHOYP_BRAFLDRAFT_284846.2.2,,,,,,,SEC63_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp141295_c0_seq3,2077,38.3245,0.3361155,0,7,,1.00E-10,O75643,U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD),U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD),GO:0005524; GO:0004004; GO:0005682; GO:0071013; GO:0000354; GO:0003676; GO:0005654,ATP binding; ATP-dependent RNA helicase activity; U5 snRNP; catalytic step 2 spliceosome; cis assembly of pre-catalytic spliceosome; nucleic acid binding; nucleoplasm,PF00270;PF00271;PF02889;,5.00E-30,CHOYP_BRAFLDRAFT_284846.1.2,,,,,,,U520_HUMAN,Homo sapiens (Human),"cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]" comp141295_c0_seq4,1169,43.7126,0.46818762,9,0,,7.00E-128,Q5R660,Translocation protein SEC63 homolog,Translocation protein SEC63 homolog,GO:0005789; GO:0016021; GO:0001889; GO:0010259; GO:0006807; GO:0031204; GO:0008565; GO:0072001,"endoplasmic reticulum membrane; integral to membrane; liver development; multicellular organismal aging; nitrogen compound metabolic process; posttranslational protein targeting to membrane, translocation; protein transporter activity; renal system development",PF00226;PF02889;,6.00E-115,CHOYP_BRAFLDRAFT_284846.2.2,,,,,,,SEC63_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp141296_c1_seq3,2669,35.1817,0.71466819,0,14,,,,,,,,,2.00E-23,CHOYP_PHUM_PHUM237480.1.1,,,,,,,,, comp141297_c0_seq1,2378,34.9033,0.4195546,179,12,,4.00E-121,Q9H0C1,Zinc finger MYND domain-containing protein 12,Zinc finger MYND domain-containing protein 12,GO:0005622; GO:0046872,intracellular; metal ion binding,PF01753;,0,CHOYP_BRAFLDRAFT_277528.1.1,,,,,,,ZMY12_HUMAN,Homo sapiens (Human), comp141297_c0_seq2,2352,35.119,0.40486171,76,18,,4.00E-121,Q9H0C1,Zinc finger MYND domain-containing protein 12,Zinc finger MYND domain-containing protein 12,GO:0005622; GO:0046872,intracellular; metal ion binding,PF01753;,0,CHOYP_BRAFLDRAFT_277528.1.1,,,,,,,ZMY12_HUMAN,Homo sapiens (Human), comp141299_c0_seq2,1799,43.0239,0.44226058,52,275,,2.00E-122,Q7T3C7,"Reticulon-4-interacting protein 1 homolog, mitochondrial","Reticulon-4-interacting protein 1 homolog, mitochondrial",GO:0005739; GO:0016491; GO:0008270,mitochondrion; oxidoreductase activity; zinc ion binding,PF08240;,,,,,,,,,RT4I1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),eye photoreceptor cell development [GO:0042462]; retina layer formation [GO:0010842] comp141303_c0_seq1,2146,38.1174,0.5276134,0,0,,3.00E-74,Q96LW4,Coiled-coil domain-containing protein 111 (DNA-directed primase/polymerase protein),DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111),GO:0003896,DNA primase activity,,,,,,,,,,CC111_HUMAN,Homo sapiens (Human),mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp141303_c0_seq2,2134,38.0037,0.52070007,0,0,,2.00E-78,Q08DZ8,Coiled-coil domain-containing protein 111 (DNA-directed primase/polymerase protein),DNA-directed primase/polymerase protein (EC 2.7.7.-) (Coiled-coil domain-containing protein 111),GO:0003896,DNA primase activity,,,,,,,,,,CC111_BOVIN,Bos taurus (Bovine),mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp141303_c0_seq3,2102,38.4872,0.54181094,0,11,,2.00E-74,Q96LW4,Coiled-coil domain-containing protein 111 (DNA-directed primase/polymerase protein),DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111),GO:0003896,DNA primase activity,,,,,,,,,,CC111_HUMAN,Homo sapiens (Human),mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp141303_c0_seq4,2114,38.4106,0.52776217,0,0,,3.00E-78,Q08DZ8,Coiled-coil domain-containing protein 111 (DNA-directed primase/polymerase protein),DNA-directed primase/polymerase protein (EC 2.7.7.-) (Coiled-coil domain-containing protein 111),GO:0003896,DNA primase activity,,,,,,,,,,CC111_BOVIN,Bos taurus (Bovine),mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp141307_c0_seq1,804,46.393,0.55796309,0,0,,2.00E-55,Q6GMK0,"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)","Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)",GO:0000139; GO:0008454; GO:0016021; GO:0046872; GO:0006486,"Golgi membrane; alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; integral to membrane; metal ion binding; protein glycosylation",PF04666;,4.00E-39,CHOYP_MGT4B.1.1,,,,,,,MGT4B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),N-glycan processing [GO:0006491] comp141307_c0_seq3,2278,41.0009,0.49244422,81,195,,5.00E-171,Q6GMK0,"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)","Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)",GO:0000139; GO:0008454; GO:0016021; GO:0046872; GO:0006486,"Golgi membrane; alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; integral to membrane; metal ion binding; protein glycosylation",PF04666;,6.00E-93,CHOYP_MGT4B.1.1,,,,,,,MGT4B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),N-glycan processing [GO:0006491] comp141311_c1_seq1,2340,39.8291,0.44280674,17,58,,7.00E-175,P20585,DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1),DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1),GO:0005524; GO:0008094; GO:0032302; GO:0000403; GO:0019237; GO:0003684; GO:0000406; GO:0000404; GO:0043570; GO:0000710; GO:0045910; GO:0000228; GO:0051096; GO:0007131; GO:0016447,ATP binding; DNA-dependent ATPase activity; MutSbeta complex; Y-form DNA binding; centromeric DNA binding; damaged DNA binding; double-strand/single-strand DNA junction binding; loop DNA binding; maintenance of DNA repeat elements; meiotic mismatch repair; negative regulation of DNA recombination; nuclear chromosome; positive regulation of helicase activity; reciprocal meiotic recombination; somatic recombination of immunoglobulin gene segments,PF01624;PF05188;PF05192;PF00488;,3.00E-40,CHOYP_MSH3.1.2,,,,,,,MSH3_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; reciprocal meiotic recombination [GO:0007131] comp141311_c1_seq2,2890,40.7612,0.43351208,35,76,,0,P20585,DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1),DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1),GO:0005524; GO:0008094; GO:0032302; GO:0000403; GO:0019237; GO:0003684; GO:0000406; GO:0000404; GO:0043570; GO:0000710; GO:0045910; GO:0000228; GO:0051096; GO:0007131; GO:0016447,ATP binding; DNA-dependent ATPase activity; MutSbeta complex; Y-form DNA binding; centromeric DNA binding; damaged DNA binding; double-strand/single-strand DNA junction binding; loop DNA binding; maintenance of DNA repeat elements; meiotic mismatch repair; negative regulation of DNA recombination; nuclear chromosome; positive regulation of helicase activity; reciprocal meiotic recombination; somatic recombination of immunoglobulin gene segments,PF01624;PF05188;PF05192;PF00488;,,,,,,,,,MSH3_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; reciprocal meiotic recombination [GO:0007131] comp141311_c1_seq3,2108,40.3226,0.46770797,8,38,,1.00E-68,A5UZK7,DNA mismatch repair protein MutS,DNA mismatch repair protein MutS,GO:0005524; GO:0003684; GO:0006298; GO:0030983,ATP binding; damaged DNA binding; mismatch repair; mismatched DNA binding,PF01624;PF05188;PF05192;PF05190;PF00488;,3.00E-40,CHOYP_MSH3.1.2,,,,,,,MUTS_ROSS1,Roseiflexus sp. (strain RS-1),mismatch repair [GO:0006298] comp141312_c0_seq1,1909,44.264,0.6834759,215,2087,,0,Q922B2,"Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)","Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)",GO:0005524; GO:0004815; GO:0006422; GO:0005737; GO:0003676,ATP binding; aspartate-tRNA ligase activity; aspartyl-tRNA aminoacylation; cytoplasm; nucleic acid binding,PF00152;PF01336;,0,CHOYP_LOC100186203.1.1,,,,,,,SYDC_MOUSE,Mus musculus (Mouse),aspartyl-tRNA aminoacylation [GO:0006422] comp141315_c0_seq13,2196,39.2532,0.25135662,0,0,,5.00E-11,Q5RDX3,CST complex subunit CTC1 (Conserved telomere maintenance component 1),CST complex subunit CTC1 (Conserved telomere maintenance component 1),GO:0000781; GO:0005634; GO:0045740; GO:0003697,"chromosome, telomeric region; nucleus; positive regulation of DNA replication; single-stranded DNA binding",PF15489;,,,,,,,,,CTC1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),positive regulation of DNA replication [GO:0045740] comp141315_c0_seq3,2299,38.93,0.23243597,1,26,,2.00E-24,Q2NKJ3,CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B),CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B),GO:0070188; GO:0048539; GO:0071425; GO:0035264; GO:0045740; GO:0048146; GO:0010389; GO:0090399; GO:0006974; GO:0003697; GO:0048536; GO:0000723; GO:0010833; GO:0048538,Stn1-Ten1 complex; bone marrow development; hematopoietic stem cell proliferation; multicellular organism growth; positive regulation of DNA replication; positive regulation of fibroblast proliferation; regulation of G2/M transition of mitotic cell cycle; replicative senescence; response to DNA damage stimulus; single-stranded DNA binding; spleen development; telomere maintenance; telomere maintenance via telomere lengthening; thymus development,PF15489;,,,,,,,,,CTC1_HUMAN,Homo sapiens (Human),bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538] comp141315_c0_seq4,3553,40.304,0.21722861,0,0,,4.00E-13,Q5SUQ9,CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1),CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1),GO:0070188; GO:0048539; GO:0071425; GO:0035264; GO:0045740; GO:0048146; GO:0010389; GO:0090399; GO:0006974; GO:0003697; GO:0048536; GO:0010833; GO:0048538,Stn1-Ten1 complex; bone marrow development; hematopoietic stem cell proliferation; multicellular organism growth; positive regulation of DNA replication; positive regulation of fibroblast proliferation; regulation of G2/M transition of mitotic cell cycle; replicative senescence; response to DNA damage stimulus; single-stranded DNA binding; spleen development; telomere maintenance via telomere lengthening; thymus development,PF15489;,,,,,,,,,CTC1_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538] comp141315_c0_seq6,2237,39.1149,0.22491991,0,0,,2.00E-13,Q5SUQ9,CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1),CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1),GO:0070188; GO:0048539; GO:0071425; GO:0035264; GO:0045740; GO:0048146; GO:0010389; GO:0090399; GO:0006974; GO:0003697; GO:0048536; GO:0010833; GO:0048538,Stn1-Ten1 complex; bone marrow development; hematopoietic stem cell proliferation; multicellular organism growth; positive regulation of DNA replication; positive regulation of fibroblast proliferation; regulation of G2/M transition of mitotic cell cycle; replicative senescence; response to DNA damage stimulus; single-stranded DNA binding; spleen development; telomere maintenance via telomere lengthening; thymus development,PF15489;,,,,,,,,,CTC1_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538] comp141315_c0_seq7,3615,40.1107,0.21563186,13,7,,1.00E-23,Q2NKJ3,CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B),CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B),GO:0070188; GO:0048539; GO:0071425; GO:0035264; GO:0045740; GO:0048146; GO:0010389; GO:0090399; GO:0006974; GO:0003697; GO:0048536; GO:0000723; GO:0010833; GO:0048538,Stn1-Ten1 complex; bone marrow development; hematopoietic stem cell proliferation; multicellular organism growth; positive regulation of DNA replication; positive regulation of fibroblast proliferation; regulation of G2/M transition of mitotic cell cycle; replicative senescence; response to DNA damage stimulus; single-stranded DNA binding; spleen development; telomere maintenance; telomere maintenance via telomere lengthening; thymus development,PF15489;,,,,,,,,,CTC1_HUMAN,Homo sapiens (Human),bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538] comp141316_c1_seq2,2480,45.4032,0.51762014,0,0,,3.00E-10,Q9CZK6,Ankyrin repeat and SAM domain-containing protein 3,Ankyrin repeat and SAM domain-containing protein 3,,,PF12796;PF00536;,,,,,,,,,ANKS3_MOUSE,Mus musculus (Mouse), comp141316_c1_seq3,753,43.6919,0.7013183,15,15,,,,,,,,,6.00E-75,CHOYP_BICC1.1.1,,,,,,,,, comp141316_c1_seq4,2958,44.8952,0.53725889,12,24,,2.00E-128,Q9H694,Protein bicaudal C homolog 1 (Bic-C),Protein bicaudal C homolog 1 (Bic-C),GO:0003723; GO:0007275; GO:0090090,RNA binding; multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway,PF00013;PF00536;,3.00E-149,CHOYP_BICC1.1.1,,,,,,,BICC1_HUMAN,Homo sapiens (Human),determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; negative regulation of canonical Wnt signaling pathway [GO:0090090] comp141316_c1_seq6,2629,45.3024,0.52025644,0,0,,3.00E-09,Q8VDJ3,Vigilin (High density lipoprotein-binding protein) (HDL-binding protein),Vigilin (High density lipoprotein-binding protein) (HDL-binding protein),GO:0003723; GO:0008203; GO:0005737; GO:0034364; GO:0006869; GO:0005634,RNA binding; cholesterol metabolic process; cytoplasm; high-density lipoprotein particle; lipid transport; nucleus,PF00013;,,,,,,,,,VIGLN_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869] comp141318_c0_seq1,1073,38.6766,0.51223395,9,59,,1.00E-10,C0H419,Biotin/lipoyl attachment protein (BLAP),Biotin/lipoyl attachment protein (BLAP),,,PF00364;,,,,,,,,,BLAP_BACSU,Bacillus subtilis (strain 168), comp141318_c0_seq3,2792,40.9026,0.48132244,200,261,,0,Q612F5,"Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)","Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)",GO:0005524; GO:0004075; GO:0046872; GO:0005759; GO:0004658,ATP binding; biotin carboxylase activity; metal ion binding; mitochondrial matrix; propionyl-CoA carboxylase activity,PF02785;PF00289;PF00364;PF02786;,0,CHOYP_PCCA.2.2,,,,,,,PCCA_CAEBR,Caenorhabditis briggsae, comp141318_c2_seq1,247,45.749,0.31795393,4,0,,3.00E-27,Q5R7V3,Acyl-CoA-binding domain-containing protein 5,Acyl-CoA-binding domain-containing protein 5,GO:0000062; GO:0016021; GO:0008289; GO:0005778; GO:0006810,fatty-acyl-CoA binding; integral to membrane; lipid binding; peroxisomal membrane; transport,PF00887;,1.00E-26,CHOYP_ACBD5.2.2,,,,,,,ACBD5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),pexophagy [GO:0030242]; transport [GO:0006810] comp141319_c0_seq1,1359,42.3841,0.24726387,65,300,,4.00E-77,Q4R3I0,Metaxin-1 (Mitochondrial outer membrane import complex protein 1),Metaxin-1 (Mitochondrial outer membrane import complex protein 1),GO:0016021; GO:0005741; GO:0006626,integral to membrane; mitochondrial outer membrane; protein targeting to mitochondrion,PF17171;PF10568;,,,,,,,,,MTX1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein targeting to mitochondrion [GO:0006626] comp141319_c0_seq2,1377,42.0479,0.29759578,63,221,,2.00E-25,O88441,Metaxin-2 (Mitochondrial outer membrane import complex protein 2),Metaxin-2 (Mitochondrial outer membrane import complex protein 2),GO:0005741; GO:0005739; GO:0006626,mitochondrial outer membrane; mitochondrion; protein targeting to mitochondrion,PF17171;PF10568;,,,,,,,,,MTX2_MOUSE,Mus musculus (Mouse),protein targeting to mitochondrion [GO:0006626] comp141322_c0_seq1,959,45.3597,0.46694633,140,79,,2.00E-45,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,1.00E-15,CHOYP_TITIN.19.19,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp141322_c0_seq2,571,46.5849,0.45294257,16,7,,5.00E-09,Q7ZW34,Contactin-5,Contactin-5,GO:0031225; GO:0007155; GO:0005886,anchored to membrane; cell adhesion; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605] comp141325_c0_seq1,396,44.9495,0.40510462,7,0,,,,,,,,,4.00E-36,CHOYP_GCP2.1.1,,,,,,,,, comp141325_c0_seq6,898,41.0913,0.37309586,27,25,,1.00E-115,Q921G8,Gamma-tubulin complex component 2 (GCP-2),Gamma-tubulin complex component 2 (GCP-2),GO:0005737; GO:0005874; GO:0000226; GO:0005815; GO:0000922,cytoplasm; microtubule; microtubule cytoskeleton organization; microtubule organizing center; spindle pole,PF04130;,2.00E-139,CHOYP_GCP2.1.1,,,,,,,GCP2_MOUSE,Mus musculus (Mouse),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; mitotic spindle assembly [GO:0090307] comp141326_c0_seq1,1158,36.1831,0.82904211,63,438,,1.00E-80,Q3SZE9,Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC),Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC),GO:0003924; GO:0000902; GO:0005829; GO:0032391; GO:0007023,GTPase activity; cell morphogenesis; cytosol; photoreceptor connecting cilium; post-chaperonin tubulin folding pathway,PF07986;PF16752;,1.00E-27,CHOYP_BRAFLDRAFT_84941.1.1,,,,,,,TBCC_BOVIN,Bos taurus (Bovine),cell morphogenesis [GO:0000902]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] comp141327_c0_seq1,1939,35.9464,0.48947886,503,3857,,1.00E-126,Q3T0F5,Ras-related protein Rab-7a,Ras-related protein Rab-7a,GO:0005525; GO:0045022; GO:0005770; GO:0005764; GO:0042470; GO:0045335; GO:0030670; GO:0090383; GO:0090385; GO:0015031; GO:0007264,GTP binding; early endosome to late endosome transport; late endosome; lysosome; melanosome; phagocytic vesicle; phagocytic vesicle membrane; phagosome acidification; phagosome-lysosome fusion; protein transport; small GTPase mediated signal transduction,PF00071;,1.00E-152,CHOYP_RAB7A.2.2,9.00E-31,ruditapes_c16665,,,,,RAB7A_BOVIN,Bos taurus (Bovine),early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; lipophagy [GO:0061724]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp141329_c1_seq1,2277,36.144,0.35145984,173,1079,,,,,,,,,2.00E-11,CHOYP_CDCA3.1.1,,,,,,,,, comp141330_c1_seq1,1624,42.6108,1.03203094,35,0,,2.00E-33,Q9V576,Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen),Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen),GO:0045177; GO:0050829; GO:0009880; GO:0035234; GO:0035233; GO:0016021; GO:0045824; GO:0007424; GO:0008195; GO:0007280; GO:0042803; GO:0005918; GO:0019991,apical part of cell; defense response to Gram-negative bacterium; embryonic pattern specification; germ cell programmed cell death; germ cell repulsion; integral to membrane; negative regulation of innate immune response; open tracheal system development; phosphatidate phosphatase activity; pole cell migration; protein homodimerization activity; septate junction; septate junction assembly,PF01569;,,,,,,,,,WUN_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; dephosphorylation [GO:0016311]; ectopic germ cell programmed cell death [GO:0035234]; embryonic pattern specification [GO:0009880]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165] comp141330_c1_seq2,1858,41.9268,1.07853407,95,32,,7.00E-36,O14495,Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP),Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP),GO:0005794; GO:0005912; GO:0001568; GO:0044329; GO:0044328; GO:0044330; GO:0001702; GO:0008354; GO:0034109; GO:0016021; GO:0042577; GO:0001933; GO:0008195; GO:0006644; GO:0004721; GO:0005886; GO:0050731; GO:0051091; GO:0050821; GO:0030111; GO:0044281; GO:0030148,Golgi apparatus; adherens junction; blood vessel development; canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion; canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration; canonical Wnt receptor signaling pathway involved in positive regulation of wound healing; gastrulation with mouth forming second; germ cell migration; homotypic cell-cell adhesion; integral to membrane; lipid phosphatase activity; negative regulation of protein phosphorylation; phosphatidate phosphatase activity; phospholipid metabolic process; phosphoprotein phosphatase activity; plasma membrane; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of sequence-specific DNA binding transcription factor activity; protein stabilization; regulation of Wnt receptor signaling pathway; small molecule metabolic process; sphingolipid biosynthetic process,PF01569;,1.00E-11,CHOYP_LPP3.1.2,,,,,,,LPP3_HUMAN,Homo sapiens (Human),Bergmann glial cell differentiation [GO:0060020]; blood vessel development [GO:0001568]; canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion [GO:0044329]; canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration [GO:0044328]; canonical Wnt signaling pathway involved in positive regulation of wound healing [GO:0044330]; gastrulation with mouth forming second [GO:0001702]; germ cell migration [GO:0008354]; homotypic cell-cell adhesion [GO:0034109]; lipid metabolic process [GO:0006629]; negative regulation of protein phosphorylation [GO:0001933]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein stabilization [GO:0050821]; regulation of sphingolipid mediated signaling pathway [GO:1902068]; regulation of Wnt signaling pathway [GO:0030111]; sphingolipid biosynthetic process [GO:0030148] comp141333_c0_seq2,1423,40.1968,0.38952112,1,0,,,,,,,,,5.00E-130,CHOYP_CUL4B.1.1,,,,,,,,, comp141333_c0_seq3,1957,37.9152,0.51036304,0,0,,2.00E-33,P53202,Cullin-3 (Cullin-B),Cullin-3 (Cullin-B),GO:0031463; GO:0042787; GO:0004842,Cul3-RING ubiquitin ligase complex; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00888;PF10557;,,,,,,,,,CUL3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141333_c0_seq5,3211,39.0221,0.46696717,0,0,,0,Q13619,Cullin-4A (CUL-4A),Cullin-4A (CUL-4A),GO:0031464; GO:0006281; GO:0000082; GO:0007050; GO:0097193; GO:0019048; GO:0008285; GO:0016567; GO:0007346; GO:0051246; GO:0006511,Cul4A-RING ubiquitin ligase complex; DNA repair; G1/S transition of mitotic cell cycle; cell cycle arrest; intrinsic apoptotic signaling pathway; modulation by virus of host morphology or physiology; negative regulation of cell proliferation; protein ubiquitination; regulation of mitotic cell cycle; regulation of protein metabolic process; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,0,CHOYP_CUL4B.1.1,,,,,,,CUL4A_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; G1/S transition of mitotic cell cycle [GO:0000082]; global genome nucleotide-excision repair [GO:0070911]; hemopoiesis [GO:0030097]; intrinsic apoptotic signaling pathway [GO:0097193]; in utero embryonic development [GO:0001701]; negative regulation of cell proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of DNA damage checkpoint [GO:2000001]; regulation of nucleotide-excision repair [GO:2000819]; regulation of protein metabolic process [GO:0051246]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]" comp141333_c0_seq6,3197,39.0053,0.47992485,0,0,,0,Q13619,Cullin-4A (CUL-4A),Cullin-4A (CUL-4A),GO:0031464; GO:0006281; GO:0000082; GO:0007050; GO:0097193; GO:0019048; GO:0008285; GO:0016567; GO:0007346; GO:0051246; GO:0006511,Cul4A-RING ubiquitin ligase complex; DNA repair; G1/S transition of mitotic cell cycle; cell cycle arrest; intrinsic apoptotic signaling pathway; modulation by virus of host morphology or physiology; negative regulation of cell proliferation; protein ubiquitination; regulation of mitotic cell cycle; regulation of protein metabolic process; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,,,,,,,,,CUL4A_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; G1/S transition of mitotic cell cycle [GO:0000082]; global genome nucleotide-excision repair [GO:0070911]; hemopoiesis [GO:0030097]; intrinsic apoptotic signaling pathway [GO:0097193]; in utero embryonic development [GO:0001701]; negative regulation of cell proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of DNA damage checkpoint [GO:2000001]; regulation of nucleotide-excision repair [GO:2000819]; regulation of protein metabolic process [GO:0051246]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]" comp141333_c0_seq7,1943,37.8796,0.53449436,0,0,,2.00E-33,P53202,Cullin-3 (Cullin-B),Cullin-3 (Cullin-B),GO:0031463; GO:0042787; GO:0004842,Cul3-RING ubiquitin ligase complex; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00888;PF10557;,,,,,,,,,CUL3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141334_c0_seq1,1686,41.9929,0.79588226,75,1738,,4.00E-93,O01404,Peptidylglycine alpha-hydroxylating monooxygenase (dPHM) (EC 1.14.17.3),Peptidylglycine alpha-hydroxylating monooxygenase (dPHM) (EC 1.14.17.3),GO:0005507; GO:0005615; GO:0016020; GO:0007613; GO:0032504; GO:0006518; GO:0004504,copper ion binding; extracellular space; membrane; memory; multicellular organism reproduction; peptide metabolic process; peptidylglycine monooxygenase activity,PF03712;PF01082;,4.00E-43,CHOYP_LOC100876663.1.1,9.00E-62,ruditapes_c7909,,,,,PHM_DROME,Drosophila melanogaster (Fruit fly),memory [GO:0007613]; multicellular organism reproduction [GO:0032504]; peptide amidation [GO:0001519]; regulation of imaginal disc-derived wing size [GO:0044719]; response to fungus [GO:0009620] comp141337_c0_seq2,1211,44.5912,1.15349044,251,10,,5.00E-06,P98074,Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain],Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain],GO:0016021; GO:0006508; GO:0005044; GO:0004252,integral to membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00431;PF00057;PF00629;PF01390;PF00530;PF00089;,,,,,,,,,ENTK_PIG,Sus scrofa (Pig), comp141340_c0_seq4,2081,47.333,0.50938432,51,119,,0,P51400,Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase),Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase),GO:0006396; GO:0006382; GO:0003726; GO:0003725; GO:0016556; GO:0006397; GO:0046872; GO:0030336; GO:0008285; GO:0044387; GO:0005730; GO:0005654; GO:0045070; GO:0051726,RNA processing; adenosine to inosine editing; double-stranded RNA adenosine deaminase activity; double-stranded RNA binding; mRNA modification; mRNA processing; metal ion binding; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; nucleoplasm; positive regulation of viral genome replication; regulation of cell cycle,PF02137;PF00035;,8.00E-53,CHOYP_RED1.2.2,,,,,,,RED1_RAT,Rattus norvegicus (Rat),adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396] comp141340_c0_seq6,1233,44.85,0.39019789,0,13,,3.00E-24,Q5ZIL4,Spermatid perinuclear RNA-binding protein,Spermatid perinuclear RNA-binding protein,GO:0003677; GO:0003723; GO:0030154; GO:0005737; GO:0007275; GO:0005634; GO:0007283,DNA binding; RNA binding; cell differentiation; cytoplasm; multicellular organismal development; nucleus; spermatogenesis,PF00035;PF07528;,,,,,,,,,STRBP_CHICK,Gallus gallus (Chicken),mechanosensory behavior [GO:0007638]; multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp141342_c0_seq1,2510,41.5538,0.31764711,206,1722,,9.00E-156,Q9BVQ7,Spermatogenesis-associated protein 5-like protein 1,Spermatogenesis-associated protein 5-like protein 1,GO:0005524; GO:0006919; GO:0070842; GO:0005737; GO:0017111; GO:0043234; GO:0006511,ATP binding; activation of cysteine-type endopeptidase activity involved in apoptotic process; aggresome assembly; cytoplasm; nucleoside-triphosphatase activity; protein complex; ubiquitin-dependent protein catabolic process,PF00004;,5.00E-44,CHOYP_BRAFLDRAFT_90046.1.1,,,,,,,SPA5L_HUMAN,Homo sapiens (Human), comp141346_c0_seq3,1386,42.5685,0.72574775,63,501,,2.00E-13,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp141348_c0_seq1,1174,43.7819,0.4993932,153,19,,,,,,,,,3.00E-99,CHOYP_LOC100372232.2.6,,,,,,,,, comp141348_c1_seq7,1149,44.9956,0.60923971,117,28,,8.00E-140,Q8CDK2,Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),GO:0005829; GO:0004181; GO:0006508; GO:0008270,cytosol; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,0,CHOYP_LOC100372232.1.6,,,,,,,CBPC2_MOUSE,Mus musculus (Mouse),protein side chain deglutamylation [GO:0035610] comp141353_c0_seq1,751,39.281,0.44959609,0,0,,5.00E-16,Q9UUK2,Histone acetyltransferase gcn5 (EC 2.3.1.48),Histone acetyltransferase gcn5 (EC 2.3.1.48),GO:0010484; GO:0000124; GO:0006338; GO:0000122; GO:0000790; GO:0007131; GO:0006351,"H3 histone acetyltransferase activity; SAGA complex; chromatin remodeling; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; reciprocal meiotic recombination; transcription, DNA-dependent",PF00583;PF00439;,,,,,,,,,GCN5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; negative regulation of leucine import [GO:0060358]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; reciprocal meiotic recombination [GO:0007131]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp141353_c0_seq2,4793,40.9556,0.4691571,440,651,,1.00E-46,Q9NRL2,Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1),Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1),GO:0016590; GO:0008623; GO:0006261; GO:0006338; GO:0000228; GO:0006355; GO:0006351; GO:0008270,"ACF complex; CHRAC; DNA-dependent DNA replication; chromatin remodeling; nuclear chromosome; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF00628;PF10537;PF15612;PF15613;,2.00E-33,CHOYP_LOC100120677.1.1,,,,,,,BAZ1A_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; DNA-dependent DNA replication [GO:0006261]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141357_c0_seq2,2108,42.0778,0.51483921,114,501,,0,Q28GH3,SUMO-activating enzyme subunit 2 (EC 6.3.2.-) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2),SUMO-activating enzyme subunit 2 (EC 6.3.2.-) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2),GO:0005524; GO:0019948; GO:0005737; GO:0016874; GO:0046872; GO:0005634; GO:0016925,ATP binding; SUMO activating enzyme activity; cytoplasm; ligase activity; metal ion binding; nucleus; protein sumoylation,PF00899;PF14732;PF16195;,0,CHOYP_SAE2.1.1,,,,,,,SAE2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein sumoylation [GO:0016925] comp141358_c0_seq3,1987,34.7257,0.4781146,0,0,,2.00E-86,Q9QZB9,Dynactin subunit 5 (Dynactin subunit p25),Dynactin subunit 5 (Dynactin subunit p25),GO:0005813; GO:0000777; GO:0005737,centrosome; condensed chromosome kinetochore; cytoplasm,PF00132;,2.00E-110,CHOYP_LOC752555.1.1,,,,,,,DCTN5_MOUSE,Mus musculus (Mouse),aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281] comp141359_c0_seq1,2058,45.4325,0.5078132,2296,2713,,0,P31335,Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)],Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)],GO:0006189; GO:0003937; GO:0005829; GO:0004643; GO:0006144,'de novo' IMP biosynthetic process; IMP cyclohydrolase activity; cytosol; phosphoribosylaminoimidazolecarboxamide formyltransferase activity; purine nucleobase metabolic process,PF01808;PF02142;,0,CHOYP_ATIC.1.1,,,,,,,PUR9_CHICK,Gallus gallus (Chicken),'de novo' IMP biosynthetic process [GO:0006189] comp141360_c1_seq1,3990,36.5915,0.4408388,57,731,,1.00E-33,Q5TJE1,Death domain-associated protein 6 (Daxx),Death domain-associated protein 6 (Daxx),GO:0016605; GO:0030521; GO:0006915; GO:0005829; GO:0000792; GO:0000281; GO:0045892; GO:0005730; GO:0042803; GO:0031396; GO:0008134; GO:0006351,"PML body; androgen receptor signaling pathway; apoptotic process; cytosol; heterochromatin; mitotic cytokinesis; negative regulation of transcription, DNA-dependent; nucleolus; protein homodimerization activity; regulation of protein ubiquitination; transcription factor binding; transcription, DNA-dependent",PF03344;,,,,,,,,,DAXX_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),"apoptotic process [GO:0006915]; chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of protein ubiquitination [GO:0031396]; transcription, DNA-templated [GO:0006351]" comp141360_c1_seq3,1611,38.7958,0.52543498,0,0,,4.00E-21,O35613,Death domain-associated protein 6 (Daxx),Death domain-associated protein 6 (Daxx),GO:0016605; GO:0050681; GO:0030521; GO:0097190; GO:0005829; GO:0000792; GO:0000281; GO:0045892; GO:0005730; GO:2001235; GO:0042803; GO:0031396; GO:0003713; GO:0003714; GO:0008134; GO:0006351,"PML body; androgen receptor binding; androgen receptor signaling pathway; apoptotic signaling pathway; cytosol; heterochromatin; mitotic cytokinesis; negative regulation of transcription, DNA-dependent; nucleolus; positive regulation of apoptotic signaling pathway; protein homodimerization activity; regulation of protein ubiquitination; transcription coactivator activity; transcription corepressor activity; transcription factor binding; transcription, DNA-dependent",PF03344;,,,,,,,,,DAXX_MOUSE,Mus musculus (Mouse),"androgen receptor signaling pathway [GO:0030521]; apoptotic signaling pathway [GO:0097190]; chromatin remodeling [GO:0006338]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron death [GO:1901216]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141361_c1_seq1,1544,44.7539,0.40863269,57,17,,4.00E-74,A6H8T2,Protein CASC1 (Cancer susceptibility candidate gene 1 protein homolog),Protein CASC1 (Cancer susceptibility candidate gene 1 protein homolog),,,PF12366;PF15927;,3.00E-152,CHOYP_LOC100377243.1.1,,,,,,,CASC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141361_c5_seq1,1067,43.7676,0.48325834,232,16,,3.00E-34,Q8T880,Axonemal 84 kDa protein (Ci-AXP83.9) (p83.9),Axonemal 84 kDa protein (Ci-AXP83.9) (p83.9),,,PF12366;PF15927;,5.00E-14,CHOYP_LOC100377243.1.1,9.00E-34,ruditapes_c20572,,,,,AXP83_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis), comp141363_c0_seq1,1796,43.2628,0.56016227,12,0,,1.00E-25,Q08050,Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells),Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells),GO:0003677; GO:0008301; GO:0006978; GO:0006281; GO:0000086; GO:0003705; GO:0007049; GO:0005737; GO:0003690; GO:0009790; GO:0001889; GO:0090344; GO:0032873; GO:0000122; GO:0005634; GO:0007389; GO:0008284; GO:2000781; GO:0045944; GO:0046578; GO:0071156; GO:0001558; GO:0042127; GO:2000377; GO:0051090; GO:0043565; GO:0003700; GO:0009888; GO:0008134; GO:0005667; GO:0006366; GO:0044212; GO:0001570,"DNA binding; DNA binding, bending; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; DNA repair; G2/M transition of mitotic cell cycle; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; cell cycle; cytoplasm; double-stranded DNA binding; embryo development; liver development; negative regulation of cell aging; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; nucleus; pattern specification process; positive regulation of cell proliferation; positive regulation of double-strand break repair; positive regulation of transcription from RNA polymerase II promoter; regulation of Ras protein signal transduction; regulation of cell cycle arrest; regulation of cell growth; regulation of cell proliferation; regulation of reactive oxygen species metabolic process; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tissue development; transcription factor binding; transcription factor complex; transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; vasculogenesis",PF00250;,4.00E-24,CHOYP_FOXM.1.1,,,,,,,FOXM1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of cell aging [GO:0090344]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell cycle arrest [GO:0071156]; regulation of cell growth [GO:0001558]; regulation of cell proliferation [GO:0042127]; regulation of Ras protein signal transduction [GO:0046578]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to cAMP [GO:0051591]; response to gonadotropin [GO:0034698]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase II promoter [GO:0006366]" comp141363_c0_seq2,2579,42.1481,0.53281971,95,33,,2.00E-25,P97691,Forkhead box protein M1 (INS-1 winged helix) (Winged-helix factor from INS-1 cells),Forkhead box protein M1 (INS-1 winged helix) (Winged-helix factor from INS-1 cells),GO:0008301; GO:0006281; GO:0000086; GO:0003705; GO:0003690; GO:0009790; GO:0001889; GO:0032873; GO:0000122; GO:0005634; GO:0007389; GO:0008284; GO:0045944; GO:0046578; GO:0071156; GO:0051090; GO:0051591; GO:0034698; GO:0043565; GO:0009888; GO:0008134; GO:0005667; GO:0001570,"DNA binding, bending; DNA repair; G2/M transition of mitotic cell cycle; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; double-stranded DNA binding; embryo development; liver development; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; nucleus; pattern specification process; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of Ras protein signal transduction; regulation of cell cycle arrest; regulation of sequence-specific DNA binding transcription factor activity; response to cAMP; response to gonadotropin stimulus; sequence-specific DNA binding; tissue development; transcription factor binding; transcription factor complex; vasculogenesis",PF00250;,,,,,,,,,FOXM1_RAT,Rattus norvegicus (Rat),"DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cAMP [GO:0051591]; response to gonadotropin [GO:0034698]; transcription, DNA-templated [GO:0006351]" comp141365_c1_seq2,1448,48.6878,0.98903075,7,47,,1.00E-67,O00624,Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2),Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2),GO:0005887; GO:0006796; GO:0005436,integral to plasma membrane; phosphate-containing compound metabolic process; sodium:phosphate symporter activity,PF07690;,,,,,,,,,NPT3_HUMAN,Homo sapiens (Human),phosphate-containing compound metabolic process [GO:0006796]; sodium ion transport [GO:0006814] comp141365_c1_seq3,1742,46.9575,1.00606094,4,57,,1.00E-109,A4FV52,Vesicular glutamate transporter 1 (VGluT1) (Solute carrier family 17 member 7),Vesicular glutamate transporter 1 (VGluT1) (Solute carrier family 17 member 7),GO:0051938; GO:0030054; GO:0060076; GO:0016021; GO:0007616; GO:0043005; GO:0006836; GO:0048786; GO:0060079; GO:0042137; GO:0015319; GO:0035249; GO:0030672,"L-glutamate import; cell junction; excitatory synapse; integral to membrane; long-term memory; neuron projection; neurotransmitter transport; presynaptic active zone; regulation of excitatory postsynaptic membrane potential; sequestering of neurotransmitter; sodium:inorganic phosphate symporter activity; synaptic transmission, glutamatergic; synaptic vesicle membrane",PF07690;,,,,,,,,,VGLU1_BOVIN,Bos taurus (Bovine),"excitatory postsynaptic potential [GO:0060079]; L-glutamate import [GO:0051938]; long-term memory [GO:0007616]; neurotransmitter transport [GO:0006836]; sequestering of neurotransmitter [GO:0042137]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle lumen acidification [GO:0097401]" comp141365_c1_seq4,1741,47.1568,1.00988558,5,58,,9.00E-127,Q9NRA2,Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),GO:0006865; GO:0030054; GO:0005887; GO:0005765; GO:0015136; GO:0015739; GO:0005351; GO:0030672,amino acid transport; cell junction; integral to plasma membrane; lysosomal membrane; sialic acid transmembrane transporter activity; sialic acid transport; sugar:hydrogen symporter activity; synaptic vesicle membrane,PF07690;,,,,,,,,,S17A5_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739] comp141367_c0_seq1,1661,38.3504,0.47640622,140,716,,4.00E-47,Q5FVR1,Probable palmitoyltransferase ZDHHC4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4) (DHHC-4),Probable palmitoyltransferase ZDHHC4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4) (DHHC-4),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDHC4_RAT,Rattus norvegicus (Rat), comp141370_c0_seq2,1749,39.4511,0.33872214,65,213,,6.00E-23,Q5T6L9,ER membrane-associated RNA degradation protein,Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein),GO:0016021,integral to membrane,PF13910;,,,,,,,,,CF070_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp141373_c0_seq1,2201,35.2113,0.47643012,0,69,,2.00E-12,Q55GU0,Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF07714;,,,,,,,,,Y9955_DICDI,Dictyostelium discoideum (Slime mold), comp141373_c0_seq2,2276,35.6766,0.55973462,30,0,,3.00E-12,Q55GU0,Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF07714;,,,,,,,,,Y9955_DICDI,Dictyostelium discoideum (Slime mold), comp141375_c0_seq1,1604,38.6534,0.55746198,256,1542,,6.00E-91,Q5FW12,TIP41-like protein,TIP41-like protein,GO:0005737,cytoplasm,PF04176;,4.00E-94,CHOYP_LOC100376749.1.1,,,,,,,TIPRL_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chordate embryonic development [GO:0043009]; negative regulation of apoptotic process [GO:0043066] comp141376_c1_seq1,1108,42.5993,1.04289726,0,7,,1.00E-17,Q3SYV5,Tetraspanin-33 (Tspan-33),Tetraspanin-33 (Tspan-33),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747] comp141378_c1_seq6,1618,41.9654,0.62248097,0,0,,3.00E-46,Q6PGZ3,TRAF3-interacting protein 1,TRAF3-interacting protein 1,GO:0042384; GO:0005737; GO:0005856; GO:0048793,cilium assembly; cytoplasm; cytoskeleton; pronephros development,,,,,,,,,,MIPT3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; regulation of microtubule cytoskeleton organization [GO:0070507] comp141378_c1_seq8,1688,40.0474,0.40659996,0,0,,3.00E-45,Q6PGZ3,TRAF3-interacting protein 1,TRAF3-interacting protein 1,GO:0042384; GO:0005737; GO:0005856; GO:0048793,cilium assembly; cytoplasm; cytoskeleton; pronephros development,,2.00E-52,CHOYP_MIPT3.1.1,,,,,,,MIPT3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; regulation of microtubule cytoskeleton organization [GO:0070507] comp141379_c0_seq2,1581,41.6825,0.35507355,0,0,,,,,,,,,0,CHOYP_BUP1.1.1,,,,,,,,, comp141379_c0_seq4,1619,41.013,0.37284592,6,77,,0,Q9UBR1,Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase),Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase),GO:0019483; GO:0003837; GO:0005829; GO:0046872; GO:0006206; GO:0046135,beta-alanine biosynthetic process; beta-ureidopropionase activity; cytosol; metal ion binding; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process,PF00795;,,,,,,,,,BUP1_HUMAN,Homo sapiens (Human),beta-alanine biosynthetic process [GO:0019483]; pyrimidine nucleoside catabolic process [GO:0046135] comp141380_c1_seq1,580,38.9655,0.77503369,38,56,,2.00E-29,Q91WR8,Glutathione peroxidase 6 (GPx-6) (GSHPx-6) (EC 1.11.1.9),Glutathione peroxidase 6 (GPx-6) (GSHPx-6) (EC 1.11.1.9),GO:0005576; GO:0004602; GO:0006979,extracellular region; glutathione peroxidase activity; response to oxidative stress,PF00255;,,,,,,,,,GPX6_MOUSE,Mus musculus (Mouse),response to oxidative stress [GO:0006979] comp141380_c2_seq1,1683,41.4141,0.84642669,0,0,,4.00E-61,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq10,4432,37.2518,0.91251817,0,0,,3.00E-78,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq11,3976,36.9215,0.9186469,8,0,,2.00E-36,Q5T197,DC-STAMP domain-containing protein 1,DC-STAMP domain-containing protein 1,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF07782;,,,,,,,,,DCST1_HUMAN,Homo sapiens (Human), comp141380_c2_seq17,4597,37.0894,0.89439954,0,0,,4.00E-78,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq25,4198,36.8032,0.91019403,0,0,,5.00E-70,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq26,2239,40.9111,0.89762445,0,0,,1.00E-72,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq35,1461,42.5051,0.8503712,0,0,,3.00E-08,Q9H295,Dendritic cell-specific transmembrane protein (DC-STAMP) (hDC-STAMP) (Dendrocyte-expressed seven transmembrane protein) (IL-four-induced protein) (FIND) (Transmembrane 7 superfamily member 4),Dendritic cell-specific transmembrane protein (DC-STAMP) (hDC-STAMP) (Dendrocyte-expressed seven transmembrane protein) (IL-four-induced protein) (FIND) (Transmembrane 7 superfamily member 4),GO:0009986; GO:0071353; GO:0036006; GO:0071356; GO:0033116; GO:0010008; GO:0030176; GO:0005887; GO:0061025; GO:0043011; GO:0030308; GO:0072675; GO:0045780; GO:0034241; GO:0045657,cell surface; cellular response to interleukin-4; cellular response to macrophage colony-stimulating factor stimulus; cellular response to tumor necrosis factor; endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; integral to endoplasmic reticulum membrane; integral to plasma membrane; membrane fusion; myeloid dendritic cell differentiation; negative regulation of cell growth; osteoclast fusion; positive regulation of bone resorption; positive regulation of macrophage fusion; positive regulation of monocyte differentiation,PF07782;,,,,,,,,,DCSTP_HUMAN,Homo sapiens (Human),cellular response to interleukin-4 [GO:0071353]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to tumor necrosis factor [GO:0071356]; membrane fusion [GO:0061025]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell growth [GO:0030308]; osteoclast differentiation [GO:0030316]; osteoclast fusion [GO:0072675]; positive regulation of bone resorption [GO:0045780]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of monocyte differentiation [GO:0045657] comp141380_c2_seq45,2404,40.3494,0.87039749,0,0,,1.00E-72,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq47,2082,41.1623,0.82885834,0,0,,8.00E-69,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141380_c2_seq5,1783,41.1666,0.90285445,0,0,,3.00E-31,Q5T197,DC-STAMP domain-containing protein 1,DC-STAMP domain-containing protein 1,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,PF07782;,,,,,,,,,DCST1_HUMAN,Homo sapiens (Human), comp141380_c2_seq6,2005,40.399,0.89417433,0,0,,1.00E-64,Q5T1A1,DC-STAMP domain-containing protein 2,DC-STAMP domain-containing protein 2,GO:0016021,integral to membrane,PF07782;,,,,,,,,,DCST2_HUMAN,Homo sapiens (Human), comp141381_c0_seq1,2273,39.9472,0.57403346,0,0,,9.00E-10,O15090,Zinc finger protein 536,Zinc finger protein 536,GO:0046872; GO:0045665; GO:0048387; GO:0005634; GO:0006355; GO:0044323; GO:0006351,"metal ion binding; negative regulation of neuron differentiation; negative regulation of retinoic acid receptor signaling pathway; nucleus; regulation of transcription, DNA-dependent; retinoic acid-responsive element binding; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN536_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq10,1971,40.4871,0.58227386,0,0,,4.00E-12,Q3UH06,Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),GO:0003677; GO:0046872; GO:0045892; GO:0016607; GO:0003700; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nuclear speck; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13912;,,,,,,,,,RREB1_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq11,1525,44.1311,0.61994198,0,0,,3.00E-11,Q8BID6,Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4),Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4),GO:0046872; GO:2001199; GO:0030853; GO:0045650; GO:0045656; GO:0003676; GO:0005634; GO:2001200; GO:0006355; GO:0006351,"metal ion binding; negative regulation of dendritic cell differentiation; negative regulation of granulocyte differentiation; negative regulation of macrophage differentiation; negative regulation of monocyte differentiation; nucleic acid binding; nucleus; positive regulation of dendritic cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT46_MOUSE,Mus musculus (Mouse),"negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq12,2237,40.7242,0.55035451,0,0,,7.00E-09,O75362,Zinc finger protein 217,Zinc finger protein 217,GO:0000118; GO:0046872; GO:0045892; GO:0003700; GO:0044212; GO:0006351,"histone deacetylase complex; metal ion binding; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",,,,,,,,,,ZN217_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq13,1525,41.6393,0.54507594,0,0,,5.00E-11,Q6DDV0,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq14,1815,43.1405,0.59268947,0,0,,4.00E-13,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq15,1551,42.8111,0.54945557,0,0,,3.00E-09,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq17,2211,39.7558,0.5269286,0,0,,2.00E-10,P31507,Protein krueppel (Fragment),Protein krueppel (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0035282,DNA binding; metal ion binding; nucleus; segmentation,PF00096;,,,,,,,,,KRUP_APIME,Apis mellifera (Honeybee),segmentation [GO:0035282] comp141381_c0_seq18,1643,44.6744,0.58661931,0,0,,3.00E-13,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq19,1935,43.2041,0.65419283,0,0,,6.00E-09,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq2,2012,39.9105,0.62488375,8,42,,2.00E-06,Q8BKX7,Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1),Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN410_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq20,2002,42.5574,0.61821003,0,0,,3.00E-10,Q9Y2Q1,Zinc finger protein 257 (Bone marrow zinc finger 4) (BMZF-4),Zinc finger protein 257 (Bone marrow zinc finger 4) (BMZF-4),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZN257_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq21,1845,44.4444,0.64792757,0,0,,2.00E-11,P18714,Gastrula zinc finger protein xFG20-1 (XlCGF20.1),Gastrula zinc finger protein xFG20-1 (XlCGF20.1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG20_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq22,1555,45.1447,0.58108747,0,0,,1.00E-10,O88282,B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein),B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein),GO:0003677; GO:0046872; GO:0000122; GO:0005634,DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus,PF00651;,,,,,,,,,BCL6B_MOUSE,Mus musculus (Mouse),myeloid cell differentiation [GO:0030099]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neurogenesis [GO:0050767] comp141381_c0_seq23,1587,41.8399,0.59112268,0,0,,3.00E-09,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq25,1596,44.4862,0.62164291,0,0,,3.00E-11,Q8BID6,Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4),Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4),GO:0046872; GO:2001199; GO:0030853; GO:0045650; GO:0045656; GO:0003676; GO:0005634; GO:2001200; GO:0006355; GO:0006351,"metal ion binding; negative regulation of dendritic cell differentiation; negative regulation of granulocyte differentiation; negative regulation of macrophage differentiation; negative regulation of monocyte differentiation; nucleic acid binding; nucleus; positive regulation of dendritic cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT46_MOUSE,Mus musculus (Mouse),"negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq26,1499,43.2288,0.58584845,0,0,,3.00E-13,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq27,1285,43.1128,0.6201633,0,0,,1.00E-12,Q3UH06,Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),GO:0003677; GO:0046872; GO:0045892; GO:0016607; GO:0003700; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nuclear speck; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13912;,,,,,,,,,RREB1_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq29,1364,43.2551,0.58089146,0,0,,1.00E-13,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq3,1788,42.2819,0.6514431,0,0,,2.00E-11,Q5TC79,Zinc finger and BTB domain-containing protein 37,Zinc finger and BTB domain-containing protein 37,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT37_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq31,1326,42.2323,0.66065448,0,0,,1.00E-12,Q6DDV0,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq32,1886,43.7964,0.67509476,0,0,,3.00E-10,Q9Y2Q1,Zinc finger protein 257 (Bone marrow zinc finger 4) (BMZF-4),Zinc finger protein 257 (Bone marrow zinc finger 4) (BMZF-4),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZN257_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq33,1460,45.8904,0.66403796,0,0,,1.00E-11,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,4.00E-15,ruditapes_c17969,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp141381_c0_seq34,1674,43.7276,0.71326675,0,0,,3.00E-10,Q6GQH4,Early growth response protein 1-A (EGR-1-A) (Xegr-1),Early growth response protein 1-A (EGR-1-A) (Xegr-1),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF11914;PF11928;,,,,,,,,,EGR1A_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq35,1633,44.4581,0.68210996,0,0,,2.00E-12,Q3UH06,Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB),GO:0003677; GO:0046872; GO:0045892; GO:0016607; GO:0003700; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nuclear speck; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13912;,,,,,,,,,RREB1_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq36,1317,42.8246,0.61360212,0,0,,2.00E-11,Q86UZ6,Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340),Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340),GO:0046872; GO:2001199; GO:0030853; GO:0045650; GO:0045656; GO:0003676; GO:0005634; GO:2001200; GO:0006355; GO:0006351,"metal ion binding; negative regulation of dendritic cell differentiation; negative regulation of granulocyte differentiation; negative regulation of macrophage differentiation; negative regulation of monocyte differentiation; nucleic acid binding; nucleus; positive regulation of dendritic cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT46_HUMAN,Homo sapiens (Human),"negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq37,1540,42.4675,0.61990054,0,0,,4.00E-13,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq38,1873,43.086,0.62171179,0,0,,1.00E-10,P31507,Protein krueppel (Fragment),Protein krueppel (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0035282,DNA binding; metal ion binding; nucleus; segmentation,PF00096;,,,,,,,,,KRUP_APIME,Apis mellifera (Honeybee),segmentation [GO:0035282] comp141381_c0_seq39,1987,41.9225,0.56160796,0,0,,2.00E-07,Q4KLI1,Zinc finger protein with KRAB and SCAN domains 1,Zinc finger protein with KRAB and SCAN domains 1,GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZKSC1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp141381_c0_seq4,2226,40.4313,0.58310249,0,0,,1.00E-12,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq6,2013,42.8217,0.56408199,38,243,,6.00E-09,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq7,1893,41.1516,0.54931134,0,0,,5.00E-12,P18714,Gastrula zinc finger protein xFG20-1 (XlCGF20.1),Gastrula zinc finger protein xFG20-1 (XlCGF20.1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG20_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq8,2049,42.0205,0.59754519,0,0,,6.00E-09,O75362,Zinc finger protein 217,Zinc finger protein 217,GO:0000118; GO:0046872; GO:0045892; GO:0003700; GO:0044212; GO:0006351,"histone deacetylase complex; metal ion binding; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",,,,,,,,,,ZN217_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp141381_c0_seq9,1531,46.0483,0.65441619,0,0,,8.00E-12,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,4.00E-15,ruditapes_c17969,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp141385_c0_seq1,1986,38.4189,0.862354,3,6,,2.00E-89,P24463,Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1),Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,,,,,,,,,CP3AC_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),hormone metabolic process [GO:0042445]; organic hydroxy compound metabolic process [GO:1901615]; progesterone metabolic process [GO:0042448]; steroid metabolic process [GO:0008202] comp141385_c0_seq2,1978,38.7765,0.79664472,4,45,,6.00E-98,Q64459,Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (Cytochrome P-450IIIAM1) (Cytochrome P-450UT),Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (Cytochrome P-450IIIAM1) (Cytochrome P-450UT),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,,,,,,,,,CP3AB_MOUSE,Mus musculus (Mouse), comp141385_c0_seq3,1991,38.8247,0.80257877,0,0,,2.00E-79,Q9HB55,Cytochrome P450 3A43 (EC 1.14.14.1),Cytochrome P450 3A43 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0044281; GO:0006805,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; small molecule metabolic process; xenobiotic metabolic process,PF00067;,,,,,,,,,CP343_HUMAN,Homo sapiens (Human), comp141385_c0_seq4,1999,38.5193,0.85171988,26,26,,2.00E-92,Q29496,Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24),Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,,,,,,,,,CP3AO_SHEEP,Ovis aries (Sheep), comp141385_c0_seq7,836,41.866,0.65647153,0,15,,8.00E-59,Q64459,Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (Cytochrome P-450IIIAM1) (Cytochrome P-450UT),Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (Cytochrome P-450IIIAM1) (Cytochrome P-450UT),GO:0070330; GO:0005789; GO:0020037; GO:0005506; GO:0004497,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity,PF00067;,,,,,,,,,CP3AB_MOUSE,Mus musculus (Mouse), comp141388_c0_seq1,1021,43.2909,0.88610972,15,104,,2.00E-63,Q920P0,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0005903; GO:0005881; GO:0006006; GO:0016020; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; brush border; cytoplasmic microtubule; glucose metabolic process; membrane; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,,,,,,,DCXR_RAT,Rattus norvegicus (Rat),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp141388_c0_seq2,1197,42.1888,0.98716514,0,0,,1.00E-12,Q81GI3,Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (ENR) (EC 1.3.1.9) (NADH-dependent enoyl-ACP reductase),Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (ENR) (EC 1.3.1.9) (NADH-dependent enoyl-ACP reductase),GO:0004318; GO:0030497; GO:0000166; GO:0051289,enoyl-[acyl-carrier-protein] reductase (NADH) activity; fatty acid elongation; nucleotide binding; protein homotetramerization,,,,,,,,,,FABI_BACCR,Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711),fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289] comp141388_c0_seq3,1352,42.0118,0.91182797,0,0,,6.00E-62,Q1JP75,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0005903; GO:0005881; GO:0006006; GO:0016020; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; brush border; cytoplasmic microtubule; glucose metabolic process; membrane; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,,,,,,,DCXR_BOVIN,Bos taurus (Bovine),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp141388_c0_seq4,866,43.7644,0.97955164,44,24,,1.00E-16,Q9GME3,Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) (Fragment),Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) (Fragment),GO:0003857; GO:0008209; GO:0004303; GO:0006703; GO:0006633; GO:0005740; GO:0005759; GO:0005886; GO:0047035,3-hydroxyacyl-CoA dehydrogenase activity; androgen metabolic process; estradiol 17-beta-dehydrogenase activity; estrogen biosynthetic process; fatty acid biosynthetic process; mitochondrial envelope; mitochondrial matrix; plasma membrane; testosterone dehydrogenase (NAD+) activity,,,,,,,,,,DHB8_CALJA,Callithrix jacchus (White-tufted-ear marmoset),estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633] comp141388_c0_seq6,903,42.5249,0.89154425,0,0,,6.00E-40,Q920P0,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0005903; GO:0005881; GO:0006006; GO:0016020; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; brush border; cytoplasmic microtubule; glucose metabolic process; membrane; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,,,,,,,DCXR_RAT,Rattus norvegicus (Rat),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp141389_c0_seq1,2490,46.9478,0.54256104,223,21,,8.00E-11,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp141390_c0_seq2,1635,39.5107,0.57126916,0,0,,2.00E-104,Q3SWT4,Protein IWS1 homolog (IWS1-like protein),Protein IWS1 homolog (IWS1-like protein),GO:0003677; GO:0008380; GO:0006397; GO:0051028; GO:0005634; GO:2001253; GO:0090239; GO:0010793; GO:0050684; GO:0006355; GO:0006351,"DNA binding; RNA splicing; mRNA processing; mRNA transport; nucleus; regulation of histone H3-K36 trimethylation; regulation of histone H4 acetylation; regulation of mRNA export from nucleus; regulation of mRNA processing; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08711;,1.00E-80,CHOYP_IWS1.1.1,,,,,,,IWS1_RAT,Rattus norvegicus (Rat),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp141390_c0_seq6,1622,39.4575,0.57710499,0,0,,1.00E-104,Q3SWT4,Protein IWS1 homolog (IWS1-like protein),Protein IWS1 homolog (IWS1-like protein),GO:0003677; GO:0008380; GO:0006397; GO:0051028; GO:0005634; GO:2001253; GO:0090239; GO:0010793; GO:0050684; GO:0006355; GO:0006351,"DNA binding; RNA splicing; mRNA processing; mRNA transport; nucleus; regulation of histone H3-K36 trimethylation; regulation of histone H4 acetylation; regulation of mRNA export from nucleus; regulation of mRNA processing; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08711;,1.00E-80,CHOYP_IWS1.1.1,,,,,,,IWS1_RAT,Rattus norvegicus (Rat),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp141391_c0_seq2,2096,40.124,0.73656497,126,1107,,2.00E-52,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,6.00E-23,CHOYP_LOC101165968.2.7,1.00E-55,ruditapes_c10412,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp141393_c0_seq1,2164,35.7671,0.509429,1336,6828,,7.00E-61,P61799,Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT),Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT),GO:0003677; GO:0006281; GO:0016787; GO:0046872; GO:0005730; GO:0005654,DNA binding; DNA repair; hydrolase activity; metal ion binding; nucleolus; nucleoplasm,PF16278;,4.00E-50,CHOYP_LOC592796.1.2,8.00E-26,ruditapes_c20838,,,,,APTX_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA repair [GO:0006281] comp141399_c0_seq2,1989,35.4449,1.13901323,34,53,,3.00E-77,Q9GUM2,"Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)","Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)",GO:0033207; GO:0075015; GO:0016021; GO:0046872; GO:0045747; GO:0006486; GO:0009636,"beta-1,4-N-acetylgalactosaminyltransferase activity; formation of infection structure on or near host; integral to membrane; metal ion binding; positive regulation of Notch signaling pathway; protein glycosylation; response to toxic substance",PF02709;PF13733;,,,,,,,,,BRE4_CAEEL,Caenorhabditis elegans,formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636] comp141400_c0_seq1,2612,44.219,0.43653717,0,0,,6.00E-35,B7ZC77,Catenin alpha-2 (Alpha N-catenin),Catenin alpha-2 (Alpha N-catenin),GO:0015629; GO:0005912; GO:0030424; GO:0007409; GO:0048854; GO:0016337; GO:0005737; GO:0048813; GO:0005886; GO:0051823; GO:0005198,actin cytoskeleton; adherens junction; axon; axonogenesis; brain morphogenesis; cell-cell adhesion; cytoplasm; dendrite morphogenesis; plasma membrane; regulation of synapse structural plasticity; structural molecule activity,PF01044;,6.00E-138,CHOYP_LOC100371831.1.1,,,,,,,CTNA2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337] comp141400_c0_seq12,1390,47.0504,0.49061072,0,0,,2.00E-123,O88327,Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1),Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1),GO:0007266; GO:0015629; GO:0007155; GO:0005829; GO:0005886; GO:0005198,Rho protein signal transduction; actin cytoskeleton; cell adhesion; cytosol; plasma membrane; structural molecule activity,PF01044;,,,,,,,,,CTNL1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; Rho protein signal transduction [GO:0007266] comp141400_c0_seq3,2616,44.6101,0.46002295,4,12,,0,O88327,Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1),Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1),GO:0007266; GO:0015629; GO:0007155; GO:0005829; GO:0005886; GO:0005198,Rho protein signal transduction; actin cytoskeleton; cell adhesion; cytosol; plasma membrane; structural molecule activity,PF01044;,2.00E-144,CHOYP_LOC100371831.1.1,,,,,,,CTNL1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; Rho protein signal transduction [GO:0007266] comp141400_c0_seq6,2637,44.7478,0.46063724,0,0,,8.00E-54,Q5R416,Catenin alpha-2 (Alpha N-catenin),Catenin alpha-2 (Alpha N-catenin),GO:0015629; GO:0005912; GO:0030424; GO:0007409; GO:0016323; GO:0048854; GO:0005913; GO:0016337; GO:0005737; GO:0048813; GO:0030027; GO:0060134; GO:0021942; GO:0051823; GO:0005198,actin cytoskeleton; adherens junction; axon; axonogenesis; basolateral plasma membrane; brain morphogenesis; cell-cell adherens junction; cell-cell adhesion; cytoplasm; dendrite morphogenesis; lamellipodium; prepulse inhibition; radial glia guided migration of Purkinje cell; regulation of synapse structural plasticity; structural molecule activity,PF01044;,,,,,,,,,CTNA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337] comp141400_c0_seq9,1468,46.3896,0.56549458,0,0,,2.00E-42,Q5R416,Catenin alpha-2 (Alpha N-catenin),Catenin alpha-2 (Alpha N-catenin),GO:0015629; GO:0005912; GO:0030424; GO:0007409; GO:0016323; GO:0048854; GO:0005913; GO:0016337; GO:0005737; GO:0048813; GO:0030027; GO:0060134; GO:0021942; GO:0051823; GO:0005198,actin cytoskeleton; adherens junction; axon; axonogenesis; basolateral plasma membrane; brain morphogenesis; cell-cell adherens junction; cell-cell adhesion; cytoplasm; dendrite morphogenesis; lamellipodium; prepulse inhibition; radial glia guided migration of Purkinje cell; regulation of synapse structural plasticity; structural molecule activity,PF01044;,5.00E-60,CHOYP_LOC100371831.1.1,,,,,,,CTNA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337] comp141403_c3_seq11,860,42.7907,0.45730683,0,0,,2.00E-14,Q5U4S8,Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),GO:0005794; GO:0000139; GO:0008120; GO:0046479; GO:0016021; GO:0007275,Golgi apparatus; Golgi membrane; ceramide glucosyltransferase activity; glycosphingolipid catabolic process; integral to membrane; multicellular organismal development,PF13506;,,,,,,,,,CEGTB_XENLA,Xenopus laevis (African clawed frog),glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275] comp141403_c3_seq20,879,42.6621,0.42328097,0,0,,3.00E-14,Q5U4S8,Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),GO:0005794; GO:0000139; GO:0008120; GO:0046479; GO:0016021; GO:0007275,Golgi apparatus; Golgi membrane; ceramide glucosyltransferase activity; glycosphingolipid catabolic process; integral to membrane; multicellular organismal development,PF13506;,,,,,,,,,CEGTB_XENLA,Xenopus laevis (African clawed frog),glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275] comp141403_c3_seq5,919,39.9347,0.42227712,0,0,,3.00E-14,Q5U4S8,Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),GO:0005794; GO:0000139; GO:0008120; GO:0046479; GO:0016021; GO:0007275,Golgi apparatus; Golgi membrane; ceramide glucosyltransferase activity; glycosphingolipid catabolic process; integral to membrane; multicellular organismal development,PF13506;,,,,,,,,,CEGTB_XENLA,Xenopus laevis (African clawed frog),glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275] comp141407_c0_seq1,1919,37.2069,0.31892435,45,67,,2.00E-41,Q8VE65,Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20),Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20),GO:0003677; GO:0000125; GO:0030914; GO:0043966; GO:0004402; GO:0051091; GO:0003700; GO:0003713; GO:0005669; GO:0033276; GO:0006367,DNA binding; PCAF complex; STAGA complex; histone H3 acetylation; histone acetyltransferase activity; positive regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription factor TFIID complex; transcription factor TFTC complex; transcription initiation from RNA polymerase II promoter,PF03847;,2.00E-54,CHOYP_TAF12.1.1,,,,,,,TAF12_MOUSE,Mus musculus (Mouse),"DNA-templated transcription, initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp141407_c0_seq2,1500,34.9333,0.24440837,2,0,,2.00E-42,Q91858,Transcription initiation factor TFIID subunit 12 (TFIID subunit p22) (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15),Transcription initiation factor TFIID subunit 12 (TFIID subunit p22) (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15),GO:0006352; GO:0006355; GO:0005669,"DNA-dependent transcription, initiation; regulation of transcription, DNA-dependent; transcription factor TFIID complex",PF03847;,,,,,,,,,TAF12_XENLA,Xenopus laevis (African clawed frog),"DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]" comp141409_c0_seq1,1627,40.6884,0.39236203,777,1728,,5.00E-143,Q1JQD2,Glutamate-rich WD repeat-containing protein 1,Glutamate-rich WD repeat-containing protein 1,GO:0005737; GO:0005730,cytoplasm; nucleolus,PF12265;PF00400;,8.00E-115,CHOYP_LOC100367612.1.1,,,,,,,GRWD1_BOVIN,Bos taurus (Bovine), comp141410_c0_seq1,2782,39.0726,0.47678281,10777,66141,,7.00E-81,Q64319,"Neutral and basic amino acid transport protein rBAT (B(0,+)-type amino acid transport protein) (NAA-TR) (D2) (Solute carrier family 3 member 1)","Neutral and basic amino acid transport protein rBAT (D2) (Solute carrier family 3 member 1) (b(0,+)-type amino acid transport protein) (NAA-TR)",GO:0006865; GO:0005975; GO:0003824; GO:0043169; GO:0005887; GO:0046982; GO:0005774,amino acid transport; carbohydrate metabolic process; catalytic activity; cation binding; integral to plasma membrane; protein heterodimerization activity; vacuolar membrane,PF00128;,7.00E-11,CHOYP_BRAFLDRAFT_265208.7.7,,,,,,,SLC31_RAT,Rattus norvegicus (Rat),amino acid transport [GO:0006865]; carbohydrate metabolic process [GO:0005975] comp141411_c0_seq1,2334,40.0171,0.77157151,32,69,,,,,,,,,7.00E-67,CHOYP_BM1_45740.1.1,,,,,,,,, comp141411_c0_seq2,2340,39.7009,0.781861,10,95,,5.00E-10,Q8NBQ7,Aquaporin-11 (AQP-11),Aquaporin-11 (AQP-11),GO:0009986; GO:0005829; GO:0030425; GO:0005783; GO:0048388; GO:0016021; GO:0005886; GO:0051260; GO:0072014; GO:0055085; GO:0005215; GO:0006833,cell surface; cytosol; dendrite; endoplasmic reticulum; endosomal lumen acidification; integral to membrane; plasma membrane; protein homooligomerization; proximal tubule development; transmembrane transport; transporter activity; water transport,PF00230;,,,,,,,,,AQP11_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260]; water transport [GO:0006833] comp141413_c2_seq6,1230,35.7724,0.66128143,0,0,,4.00E-09,Q96EL3,"39S ribosomal protein L53, mitochondrial (L53mt) (MRP-L53)","39S ribosomal protein L53, mitochondrial (L53mt) (MRP-L53)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF10780;,,,,,,,,,RM53_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126] comp141415_c0_seq1,3103,42.8617,0.61227941,3,10,,5.00E-166,Q95YJ5,Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3),Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0030154; GO:0045454; GO:0007275; GO:0004550; GO:0007283,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cell differentiation; cell redox homeostasis; multicellular organismal development; nucleoside diphosphate kinase activity; spermatogenesis,PF00334;PF00085;,,,,,,,,,TXND3_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis),cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] comp141415_c0_seq2,3151,42.7801,0.61976268,55,0,,4.00E-55,Q86XW9,Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2),Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0045454; GO:0005737; GO:0005856; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cell redox homeostasis; cytoplasm; cytoskeleton; nucleoside diphosphate kinase activity,PF00334;PF00085;,,,,,,,,,TXND6_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] comp141415_c0_seq3,3176,42.7582,0.62959104,32,0,,2.00E-166,Q95YJ5,Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3),Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0030154; GO:0045454; GO:0007275; GO:0004550; GO:0007283,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cell differentiation; cell redox homeostasis; multicellular organismal development; nucleoside diphosphate kinase activity; spermatogenesis,PF00334;PF00085;,0,CHOYP_TXND3.2.4,,,,,,,TXND3_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis),cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] comp141415_c0_seq4,3188,42.7854,0.62656642,6,0,,2.00E-153,P90666,Thioredoxin domain-containing protein 3 homolog (Intermediate chain 1) (NME/NM23 family member 8),Thioredoxin domain-containing protein 3 homolog (Intermediate chain 1) (NME/NM23 family member 8),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0030154; GO:0045454; GO:0007275; GO:0004550; GO:0007283,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cell differentiation; cell redox homeostasis; multicellular organismal development; nucleoside diphosphate kinase activity; spermatogenesis,PF00334;PF00085;,,,,,,,,,TXND3_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] comp141415_c0_seq5,1875,46.1333,0.59577095,57,7,,3.00E-26,B3EGU1,Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase),Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0005737; GO:0046872; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cytoplasm; metal ion binding; nucleoside diphosphate kinase activity,PF00334;,0,CHOYP_TXND3.2.4,,,,,,,NDK_CHLL2,Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330),CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] comp141416_c1_seq1,744,45.5645,0.42685333,57,86,,1.00E-12,Q9H611,ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (PIF1/RRM3 DNA helicase-like protein),ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (PIF1/RRM3 DNA helicase-like protein),GO:0005524; GO:0043141; GO:0033682; GO:0006310; GO:0006281; GO:0000287; GO:0005739; GO:0051974; GO:0000784; GO:0032204; GO:0017116; GO:0000723; GO:0042162,"ATP binding; ATP-dependent 5'-3' DNA helicase activity; ATP-dependent 5'-3' DNA/RNA helicase activity; DNA recombination; DNA repair; magnesium ion binding; mitochondrion; negative regulation of telomerase activity; nuclear chromosome, telomeric region; regulation of telomere maintenance; single-stranded DNA-dependent ATP-dependent DNA helicase activity; telomere maintenance; telomeric DNA binding",PF02689;PF05970;,,,,,,,,,PIF1_HUMAN,Homo sapiens (Human),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance [GO:0032204]; telomere maintenance [GO:0000723] comp141417_c0_seq2,1948,38.6037,0.29656125,51,189,,5.00E-98,Q5BKN5,Cell division cycle protein 123 homolog,Cell division cycle protein 123 homolog,GO:0007049; GO:0051301; GO:0005737,cell cycle; cell division; cytoplasm,PF07065;,9.00E-71,CHOYP_CD123.1.1,,,,,,,CD123_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle arrest [GO:0007050]; cell division [GO:0051301]; formation of cytoplasmic translation initiation complex [GO:0001732]; regulation of mitotic cell cycle [GO:0007346]; regulation of translation [GO:0006417] comp141418_c0_seq1,2045,40.1467,0.44118609,433,3569,,1.00E-151,P49005,DNA polymerase delta subunit 2 (EC 2.7.7.7) (DNA polymerase delta subunit p50),DNA polymerase delta subunit 2 (EC 2.7.7.7) (DNA polymerase delta subunit p50),GO:0003677; GO:0006271; GO:0003887; GO:0006284; GO:0000278; GO:0005654; GO:0006297; GO:0000722; GO:0032201; GO:0006283,"DNA binding; DNA strand elongation involved in DNA replication; DNA-directed DNA polymerase activity; base-excision repair; mitotic cell cycle; nucleoplasm; nucleotide-excision repair, DNA gap filling; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair",PF04042;,2.00E-97,CHOYP_BRAFLDRAFT_68004.1.1,,,,,,,DPOD2_HUMAN,Homo sapiens (Human),"DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp141420_c2_seq2,1135,43.5242,0.4283282,129,253,,3.00E-33,Q5R8V9,Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (Zinc finger C3HC-type protein 1),Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (Zinc finger C3HC-type protein 1),GO:0051301; GO:0007067; GO:0005634; GO:0016567; GO:0008270,cell division; mitosis; nucleus; protein ubiquitination; zinc ion binding,PF08600;PF07967;,,,,,,,,,NIPA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp141426_c0_seq1,2775,37.982,0.47141294,4941,56032,,0,Q5RFB6,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1),GO:0004579; GO:0005789; GO:0016021; GO:0042470; GO:0006486,dolichyl-diphosphooligosaccharide-protein glycotransferase activity; endoplasmic reticulum membrane; integral to membrane; melanosome; protein glycosylation,PF04597;,1.00E-166,CHOYP_BRAFLDRAFT_283789.1.1,2.00E-15,ruditapes2_c923,,,,,RPN1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein glycosylation [GO:0006486] comp141427_c0_seq3,1382,37.8437,0.34615743,0,0,,2.00E-113,Q0D2E8,Protein RFT1 homolog,Protein RFT1 homolog,GO:0008643; GO:0016021; GO:0005319,carbohydrate transport; integral to membrane; lipid transporter activity,PF04506;,9.00E-25,CHOYP_BRAFLDRAFT_93651.1.1,,,,,,,RFT1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),carbohydrate transport [GO:0008643]; glycolipid translocation [GO:0034203] comp141429_c0_seq1,2061,36.196,0.40018698,94,592,,5.00E-34,Q8MT80,GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV),GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV),GO:0006506; GO:0000026; GO:0005783; GO:0005789; GO:0016021,"GPI anchor biosynthetic process; alpha-1,2-mannosyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane",PF03901;,,,,,,,,,PIGZ_DROME,Drosophila melanogaster (Fruit fly),GPI anchor biosynthetic process [GO:0006506] comp141429_c0_seq2,851,36.1927,0.46710591,0,5,,2.00E-15,Q8MT80,GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV),GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV),GO:0006506; GO:0000026; GO:0005783; GO:0005789; GO:0016021,"GPI anchor biosynthetic process; alpha-1,2-mannosyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane",PF03901;,,,,,,,,,PIGZ_DROME,Drosophila melanogaster (Fruit fly),GPI anchor biosynthetic process [GO:0006506] comp141432_c0_seq1,1673,45.8458,0.47970215,155,204,,0,Q13367,AP-3 complex subunit beta-2 (Adapter-related protein complex 3 subunit beta-2) (Adaptor protein complex AP-3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP),AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP),GO:0030123; GO:0030137; GO:0008089; GO:0048490; GO:0030665; GO:0006897; GO:0006886; GO:0005634; GO:0006892; GO:0005215,AP-3 adaptor complex; COPI-coated vesicle; anterograde axon cargo transport; anterograde synaptic vesicle transport; clathrin-coated vesicle membrane; endocytosis; intracellular protein transport; nucleus; post-Golgi vesicle-mediated transport; transporter activity,PF01602;PF14796;,0,CHOYP_BRAFLDRAFT_58684.1.1,,,,,,,AP3B2_HUMAN,Homo sapiens (Human),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; post-Golgi vesicle-mediated transport [GO:0006892] comp141435_c0_seq1,1543,42.709,0.38401363,1586,5682,,0,P09623,"Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase)","Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase)",GO:0045454; GO:0004148; GO:0050660; GO:0005759,cell redox homeostasis; dihydrolipoyl dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrial matrix,PF07992;PF02852;,0,CHOYP_DLDH.1.1,,,,,,,DLDH_PIG,Sus scrofa (Pig),cell redox homeostasis [GO:0045454] comp141436_c3_seq1,2327,41.1259,0.4859047,159,694,,0,Q642T7,Digestive organ expansion factor homolog,Digestive organ expansion factor homolog,GO:0007275; GO:0005634,multicellular organismal development; nucleus,PF06862;,5.00E-94,CHOYP_DIEXF.1.1,,,,,,,DIEXF_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism development [GO:0007275]" comp141436_c3_seq3,902,43.0155,0.55207404,0,11,,4.00E-113,Q642T7,Digestive organ expansion factor homolog,Digestive organ expansion factor homolog,GO:0007275; GO:0005634,multicellular organismal development; nucleus,PF06862;,,,,,,,,,DIEXF_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism development [GO:0007275]" comp141437_c1_seq2,4043,42.5674,0.43236706,2,23,,0,Q54WN0,AP-3 complex subunit delta (Adapter-related protein complex 3 subunit delta) (Delta-adaptin),AP-3 complex subunit delta (Adaptor-related protein complex 3 subunit delta) (Delta-adaptin),GO:0030123; GO:0005794; GO:0030131; GO:0006897; GO:0010008; GO:0006886; GO:0008565,AP-3 adaptor complex; Golgi apparatus; clathrin adaptor complex; endocytosis; endosome membrane; intracellular protein transport; protein transporter activity,PF01602;PF02883;,0,CHOYP_BRAFLDRAFT_276908.1.1,1.00E-57,ruditapes_c15194,,,,,AP3D_DICDI,Dictyostelium discoideum (Slime mold),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp141437_c1_seq3,4064,42.5197,0.43102363,12,12,,0,O54774,AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin) (mBLVR1),AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin) (mBLVR1),GO:0000139; GO:0008089; GO:0048490; GO:0048007; GO:0010008; GO:0006886; GO:0030117; GO:0051138; GO:0033365; GO:0008565; GO:0061088; GO:0048499; GO:0043195; GO:0005802; GO:0006829,"Golgi membrane; anterograde axon cargo transport; anterograde synaptic vesicle transport; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; endosome membrane; intracellular protein transport; membrane coat; positive regulation of NK T cell differentiation; protein localization to organelle; protein transporter activity; regulation of sequestering of zinc ion; synaptic vesicle membrane organization; terminal bouton; trans-Golgi network; zinc ion transport",PF01602;PF06375;,0,CHOYP_BRAFLDRAFT_276908.1.1,,,,,,,AP3D1_MOUSE,Mus musculus (Mouse),"anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; antigen processing and presentation [GO:0019882]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; positive regulation of NK T cell differentiation [GO:0051138]; protein localization to membrane [GO:0072657]; protein localization to organelle [GO:0033365]; regulation of sequestering of zinc ion [GO:0061088]; synaptic vesicle membrane organization [GO:0048499]; vesicle-mediated transport [GO:0016192]; zinc II ion transport [GO:0006829]" comp141439_c0_seq1,2050,44.1951,0.40741946,80,550,,2.00E-148,Q9CZT4,DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit 5) (RNA polymerase III subunit C5) (Sex-lethal interactor homolog),DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit 5) (RNA polymerase III subunit C5) (Sex-lethal interactor homolog),GO:0003899; GO:0051607; GO:0045087; GO:0005634; GO:0006351,"DNA-directed RNA polymerase activity; defense response to virus; innate immune response; nucleus; transcription, DNA-dependent",PF04801;,4.00E-75,CHOYP_BRAFLDRAFT_118680.1.1,,,,,,,RPC5_MOUSE,Mus musculus (Mouse),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; transcription from RNA polymerase III promoter [GO:0006383] comp141439_c0_seq2,1996,44.0381,0.40997968,35,288,,5.00E-06,O74883,DNA-directed RNA polymerase III subunit rpc5 (RNA polymerase III subunit C5) (RNA polymerase III subunit C37),DNA-directed RNA polymerase III subunit rpc5 (RNA polymerase III subunit C5) (RNA polymerase III subunit C37),GO:0005666; GO:0003899; GO:0005829; GO:0006383,DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; cytosol; transcription from RNA polymerase III promoter,PF04801;,2.00E-73,CHOYP_BRAFLDRAFT_118680.1.1,,,,,,,RPC5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),transcription from RNA polymerase III promoter [GO:0006383] comp141440_c1_seq1,988,38.2591,0.50797598,114,327,,2.00E-62,Q5TYS5,Secernin-2,Secernin-2,GO:0016805; GO:0006508,dipeptidase activity; proteolysis,PF03577;,,,,,,,,,SCRN2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),exocytosis [GO:0006887] comp141440_c1_seq2,592,45.6081,0.70193538,72,89,,5.00E-57,Q0V984,Secernin-2,Secernin-2,GO:0016805; GO:0006508,dipeptidase activity; proteolysis,PF03577;,3.00E-20,CHOYP_LOC100373892.2.2,,,,,,,SCRN2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),exocytosis [GO:0006887] comp141441_c0_seq1,3167,39.9432,0.627088,679,296,,2.00E-30,Q8K1N4,Spermatogenesis-associated serine-rich protein 2 (Serine-rich spermatocytes and round spermatid 59 kDa protein) (p59scr),Spermatogenesis-associated serine-rich protein 2 (Serine-rich spermatocytes and round spermatid 59 kDa protein) (p59scr),GO:0005737,cytoplasm,PF07139;,8.00E-30,CHOYP_FGL1.1.6,,,,,,,SPAS2_MOUSE,Mus musculus (Mouse), comp141442_c0_seq1,3104,42.3003,0.55654752,17,40,,5.00E-85,Q8AYG3,Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap),Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap),GO:0005524; GO:0051301; GO:0009790; GO:0046872; GO:0007093; GO:0018108; GO:0004674; GO:0004712; GO:0004713; GO:0042246,ATP binding; cell division; embryo development; metal ion binding; mitotic cell cycle checkpoint; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; tissue regeneration,PF00069;,,,,,,,,,TTK_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),anatomical structure homeostasis [GO:0060249]; cell division [GO:0051301]; chromosome separation [GO:0051304]; embryo development [GO:0009790]; female meiosis chromosome segregation [GO:0016321]; fin regeneration [GO:0031101]; male meiosis chromosome segregation [GO:0007060]; mitotic cell cycle checkpoint [GO:0007093]; tissue regeneration [GO:0042246] comp141442_c0_seq2,3073,42.2714,0.55528518,5,0,,1.00E-79,O94235,Serine/threonine-protein kinase mph1 (EC 2.7.12.2),Serine/threonine-protein kinase mph1 (EC 2.7.12.2),GO:0005524; GO:0051301; GO:0034613; GO:0000778; GO:0005829; GO:0007127; GO:0007067; GO:0007094; GO:0044732; GO:0004674; GO:0007165,ATP binding; cell division; cellular protein localization; condensed nuclear chromosome kinetochore; cytosol; meiosis I; mitosis; mitotic spindle assembly checkpoint; mitotic spindle pole body; protein serine/threonine kinase activity; signal transduction,PF00069;,,,,,,,,,MPH1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),Bub1-Bub3 complex localization to kinetochore [GO:1990299]; cell division [GO:0051301]; cellular protein localization [GO:0034613]; chromosome separation [GO:0051304]; meiosis I [GO:0007127]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; peptidyl-threonine phosphorylation [GO:0018107]; signal transduction involved in mitotic spindle assembly checkpoint [GO:0072480] comp141443_c0_seq1,2233,35.3336,0.4880551,55,5,,,,,,,,,9.00E-21,CHOYP_LOC100891071.1.1,,,,,,,,, comp141444_c0_seq1,5257,35.4575,0.64867119,1807,5790,,2.00E-105,P08928,Lamin Dm0,Lamin Dm0,GO:0008344; GO:0007569; GO:0007417; GO:0005813; GO:0051297; GO:0040003; GO:0006342; GO:0001745; GO:0048546; GO:0035262; GO:0005638; GO:0046331; GO:0005811; GO:0005875; GO:0007084; GO:0072686; GO:0005635; GO:0071763; GO:0007097; GO:0031081; GO:0090435; GO:0005198; GO:0007430,"adult locomotory behavior; cell aging; central nervous system development; centrosome; centrosome organization; chitin-based cuticle development; chromatin silencing; compound eye morphogenesis; digestive tract morphogenesis; gonad morphogenesis; lamin filament; lateral inhibition; lipid particle; microtubule associated complex; mitotic nuclear envelope reassembly; mitotic spindle; nuclear envelope; nuclear membrane organization; nuclear migration; nuclear pore distribution; protein localization to nuclear envelope; structural molecule activity; terminal branching, open tracheal system",PF00038;PF00932;,6.00E-15,CHOYP_LMNB2.1.1,,,,,,,LAM0_DROME,Drosophila melanogaster (Fruit fly),"adult locomotory behavior [GO:0008344]; cell aging [GO:0007569]; central nervous system development [GO:0007417]; centrosome organization [GO:0051297]; chitin-based cuticle development [GO:0040003]; chromatin silencing [GO:0006342]; compound eye morphogenesis [GO:0001745]; digestive tract morphogenesis [GO:0048546]; gonad morphogenesis [GO:0035262]; heterochromatin maintenance involved in chromatin silencing [GO:0070870]; lateral inhibition [GO:0046331]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell proliferation [GO:0008285]; negative regulation of immune response [GO:0050777]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; nuclear migration [GO:0007097]; nuclear pore distribution [GO:0031081]; nucleus organization [GO:0006997]; protein localization to nuclear envelope [GO:0090435]; spermatogenesis [GO:0007283]; terminal branching, open tracheal system [GO:0007430]" comp141449_c2_seq1,881,34.9603,0.5166035,185,839,,7.00E-45,B3S3D5,DDRGK domain-containing protein 1,DDRGK domain-containing protein 1,,,PF09756;,5.00E-32,CHOYP_LOC594038.1.1,,,,,,,DDRGK_TRIAD,Trichoplax adhaerens (Trichoplax reptans), comp141450_c1_seq1,2041,44.537,0.57371234,0,9,,0,Q5R889,Putative adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2),Putative adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2),GO:0004013; GO:0006730,adenosylhomocysteinase activity; one-carbon metabolic process,PF05221;PF00670;,0,CHOYP_SAHH3.1.2,,,,,,,SAHH3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),one-carbon metabolic process [GO:0006730] comp141450_c1_seq2,2006,44.317,0.54911094,19,24,,1.00E-174,A1WXM7,Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase),Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase),GO:0004013; GO:0005737; GO:0006730,adenosylhomocysteinase activity; cytoplasm; one-carbon metabolic process,PF05221;PF00670;,0,CHOYP_LOC100121788.1.1,,,,,,,SAHH_HALHL,Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1)),one-carbon metabolic process [GO:0006730] comp141450_c1_seq5,1184,48.3953,0.63408457,0,0,,,,,,,,,0,CHOYP_SAHH3.1.2,3.00E-15,ruditapes2_lrc3157,,,,,,, comp141451_c1_seq1,948,42.616,0.60683786,0,0,,9.00E-06,A0JP86,Laminin subunit gamma-1,Laminin subunit gamma-1,GO:0005604; GO:0007155,basement membrane; cell adhesion,PF00052;PF00053;PF00055;,,,,,,,,,LAMC1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell adhesion [GO:0007155] comp141452_c0_seq1,603,42.2886,0.71950041,0,6,,,,,,,,,3.00E-27,CHOYP_WASP.1.1,,,,,,,,, comp141452_c0_seq2,1892,45.8774,0.41276496,145,912,,2.00E-42,P42768,Wiskott-Aldrich syndrome protein (WASp),Wiskott-Aldrich syndrome protein (WASp),GO:0038096; GO:0042110; GO:0050852; GO:0015629; GO:0030041; GO:0030048; GO:0008154; GO:0007596; GO:0005829; GO:0016197; GO:0008544; GO:0045087; GO:2000601; GO:0006461; GO:0005083; GO:0012506,Fc-gamma receptor signaling pathway involved in phagocytosis; T cell activation; T cell receptor signaling pathway; actin cytoskeleton; actin filament polymerization; actin filament-based movement; actin polymerization or depolymerization; blood coagulation; cytosol; endosomal transport; epidermis development; innate immune response; positive regulation of Arp2/3 complex-mediated actin nucleation; protein complex assembly; small GTPase regulator activity; vesicle membrane,PF00786;PF00568;PF02205;,,,,,,,,,WASP_HUMAN,Homo sapiens (Human),actin filament-based movement [GO:0030048]; actin filament polymerization [GO:0030041]; actin polymerization or depolymerization [GO:0008154]; blood coagulation [GO:0007596]; defense response [GO:0006952]; endosomal transport [GO:0016197]; epidermis development [GO:0008544]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; negative regulation of cell motility [GO:2000146]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein complex assembly [GO:0006461]; regulation of T cell antigen processing and presentation [GO:0002625]; T cell activation [GO:0042110]; T cell receptor signaling pathway [GO:0050852] comp141453_c0_seq1,1704,36.2676,1.06805791,171,1861,,9.00E-15,Q90WJ8,Lactose-binding lectin l-2 (Ajl-2),Lactose-binding lectin l-2 (Ajl-2),GO:0030246; GO:0050829; GO:0005576; GO:0043152,carbohydrate binding; defense response to Gram-negative bacterium; extracellular region; induction of bacterial agglutination,PF00059;,,,,,,,,,AJL2_ANGJA,Anguilla japonica (Japanese eel),defense response to Gram-negative bacterium [GO:0050829]; induction of bacterial agglutination [GO:0043152] comp141454_c1_seq1,2219,36.6832,0.45782923,4,121,,,,,,,,,8.00E-22,CHOYP_LOC100569021.1.2,,,,,,,,, comp141454_c1_seq2,2311,36.3912,0.46022258,24,52,,,,,,,,,8.00E-22,CHOYP_LOC100569021.1.2,,,,,,,,, comp141456_c1_seq2,2196,40.5282,0.84525255,153,180,,2.00E-46,Q6DDL7,Protein unc-93 homolog A (Unc-93A),Protein unc-93 homolog A (Unc-93A),GO:0016021,integral to membrane,PF05978;,,,,,,,,,UN93A_XENLA,Xenopus laevis (African clawed frog), comp141457_c0_seq2,1407,36.1763,0.41499152,106,1229,,3.00E-32,Q17QU3,Arpin,Arpin,,,PF10574;,6.00E-15,CHOYP_LOC100373090.1.1,6.00E-19,ruditapes_c14731,,,,,CO038_BOVIN,Bos taurus (Bovine),directional locomotion [GO:0033058]; negative regulation of actin nucleation [GO:0051126]; negative regulation of cell migration [GO:0030336]; negative regulation of lamellipodium morphogenesis [GO:2000393] comp141457_c1_seq2,1201,36.5529,0.42784787,160,1246,,3.00E-50,B2RYG8,Elongator complex protein 6 (Protein TMEM103),Elongator complex protein 6 (Protein TMEM103),GO:0033588; GO:0030335; GO:0006355; GO:0006351,"Elongator holoenzyme complex; positive regulation of cell migration; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09807;,,,,,,,,,ELP6_RAT,Rattus norvegicus (Rat),"positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp141458_c1_seq1,1184,39.6959,0.41400074,111,658,,9.00E-85,Q2KI56,COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b),COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b),GO:0008180; GO:0010388; GO:0005737,COP9 signalosome; cullin deneddylation; cytoplasm,PF01399;,5.00E-110,CHOYP_LOC100378691.2.2,,,,,,,CSN7B_BOVIN,Bos taurus (Bovine),cullin deneddylation [GO:0010388] comp141459_c0_seq1,1598,37.985,0.49934217,443,910,,1.00E-106,Q9UGC7,"Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a)","Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a)",GO:0005739; GO:0016149,"mitochondrion; translation release factor activity, codon specific",PF03462;PF00472;,2.00E-20,CHOYP_RF1M.1.1,2.00E-37,ruditapes_c9050,,,,,RF1ML_HUMAN,Homo sapiens (Human),mitochondrial translational termination [GO:0070126] comp141461_c0_seq1,2493,38.7485,0.54635433,128,1142,,2.00E-124,Q2TBP2,Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein),Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,HINFP_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141461_c0_seq2,1674,42.5926,0.54181479,13,36,,7.00E-24,Q9R1D1,Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog),Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog),GO:0003677; GO:0043035; GO:0016568; GO:0007059; GO:0000775; GO:0000793; GO:0010216; GO:0046872; GO:0045892; GO:0005730; GO:0005654; GO:0016584; GO:0045893; GO:0006349; GO:0035065; GO:0031060; GO:0040030; GO:0043565; GO:0003700; GO:0044212; GO:0006351,"DNA binding; chromatin insulator sequence binding; chromatin modification; chromosome segregation; chromosome, centromeric region; condensed chromosome; maintenance of DNA methylation; metal ion binding; negative regulation of transcription, DNA-dependent; nucleolus; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; regulation of gene expression by genetic imprinting; regulation of histone acetylation; regulation of histone methylation; regulation of molecular function, epigenetic; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription, DNA-dependent",,,,,,,,,,CTCF_RAT,Rattus norvegicus (Rat),"chromatin modification [GO:0016568]; chromosome segregation [GO:0007059]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; transcription, DNA-templated [GO:0006351]" comp141462_c0_seq2,3751,37.0035,0.59097786,179,0,,7.00E-32,Q8NE28,Probable inactive protein kinase-like protein SgK071 (Sugen kinase 071),Serine/threonine kinase-like domain-containing protein STKLD1 (Serine/threonine kinase-like domain-containing protein 1) (Sugen kinase 071),GO:0005524; GO:0004672,ATP binding; protein kinase activity,PF00069;,2.00E-32,CHOYP_BRAFLDRAFT_76176.1.1,,,,,,,SGK71_HUMAN,Homo sapiens (Human), comp141462_c0_seq4,3671,36.9926,0.58015593,86,8,,4.00E-22,P51954,Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1),Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1),GO:0005524; GO:0051301; GO:0030030; GO:0005813; GO:0005737; GO:0046872; GO:0007067; GO:0005634; GO:0018108; GO:0004672; GO:0004674; GO:0004713; GO:0006974; GO:0010212,ATP binding; cell division; cell projection organization; centrosome; cytoplasm; metal ion binding; mitosis; nucleus; peptidyl-tyrosine phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; response to DNA damage stimulus; response to ionizing radiation,PF00069;,,,,,,,,,NEK1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0042384]; kidney development [GO:0001822]; mitotic nuclear division [GO:0007067]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283] comp141465_c1_seq1,5782,40.7471,0.54040506,26513,43511,,0,Q6RWA9,Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 3.6.3.9) (Sodium pump subunit alpha) (TNaK1-alpha),Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 3.6.3.9) (Sodium pump subunit alpha) (TNaK1-alpha),GO:0005524; GO:0006754; GO:0016021; GO:0046872; GO:0005391,ATP binding; ATP biosynthetic process; integral to membrane; metal ion binding; sodium:potassium-exchanging ATPase activity,PF00689;PF00690;PF00122;,0,CHOYP_AT1A.1.1,0,ruditapes_c7828,,,,,AT1A_TAESO,Taenia solium (Pork tapeworm), comp141468_c0_seq1,985,41.2183,0.45462093,6,150,,4.00E-38,P81134,Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (V-ATPase M8.9 subunit),Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (V-ATPase M8.9 subunit),GO:0016021; GO:0004872,integral to membrane; receptor activity,PF07850;,,,,,,,,,RENR_BOVIN,Bos taurus (Bovine), comp141468_c0_seq2,948,31.0127,0.88637842,7,21,,,,,,,,,2.00E-13,CHOYP_BRAFLDRAFT_280496.1.1,,,,,,,,, comp141469_c0_seq1,1822,39.0779,0.32091998,42,244,,1.00E-108,A0LMC0,2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT),2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT),GO:0047304; GO:0019700; GO:0030170,2-aminoethylphosphonate-pyruvate transaminase activity; organic phosphonate catabolic process; pyridoxal phosphate binding,PF00266;,,,,,,,,,PHNW_SYNFM,Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB),organic phosphonate catabolic process [GO:0019700] comp141469_c0_seq2,1929,39.295,0.39547794,4,126,,,,,,,,,3.00E-38,CHOYP_BRAFLDRAFT_77063.1.1,,,,,,,,, comp141470_c0_seq3,2170,42.1659,0.4940064,0,0,,3.00E-26,Q5SUV2,MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1),GO:0030154; GO:0005737; GO:0016020; GO:0007275; GO:0007283; GO:0007268,cell differentiation; cytoplasm; membrane; multicellular organismal development; spermatogenesis; synaptic transmission,PF14646;,,,,,,,,,MYBPP_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp141470_c0_seq5,2832,41.3136,0.49510227,0,0,,7.00E-30,Q69CM7,MYCBP-associated protein (Organ of Corti membrane-associated protein of 106 kDa),MYCBP-associated protein (Organ of Corti membrane-associated protein of 106 kDa),GO:0030154; GO:0005737; GO:0019897; GO:0007275; GO:0007605; GO:0007283; GO:0007268,cell differentiation; cytoplasm; extrinsic to plasma membrane; multicellular organismal development; sensory perception of sound; spermatogenesis; synaptic transmission,PF14646;,,,,,,,,,MYBPP_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283] comp141472_c1_seq2,359,33.1476,0,19,19,,,,,,,,,2.00E-13,CHOYP_contig_019843,,,,,,,,, comp141473_c0_seq2,1682,34.0071,0.31184002,212,862,,4.00E-110,P36404,ADP-ribosylation factor-like protein 2,ADP-ribosylation factor-like protein 2,GO:0019003; GO:0005525; GO:0003924; GO:0005095; GO:0007049; GO:0005813; GO:0051297; GO:0016328; GO:0051457; GO:0005758; GO:0034260; GO:0005634; GO:0010811; GO:0031116; GO:0007264; GO:0070830; GO:0007021,GDP binding; GTP binding; GTPase activity; GTPase inhibitor activity; cell cycle; centrosome; centrosome organization; lateral plasma membrane; maintenance of protein location in nucleus; mitochondrial intermembrane space; negative regulation of GTPase activity; nucleus; positive regulation of cell-substrate adhesion; positive regulation of microtubule polymerization; small GTPase mediated signal transduction; tight junction assembly; tubulin complex assembly,PF00025;,1.00E-113,CHOYP_LOC100370080.1.1,,,,,,,ARL2_HUMAN,Homo sapiens (Human),bicellular tight junction assembly [GO:0070830]; cell cycle [GO:0007049]; centrosome organization [GO:0051297]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of GTPase activity [GO:0034260]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of microtubule polymerization [GO:0031116]; regulation of insulin secretion [GO:0050796]; regulation of microtubule polymerization [GO:0031113]; small GTPase mediated signal transduction [GO:0007264]; tubulin complex assembly [GO:0007021] comp141473_c1_seq1,1710,41.345,0.45184875,67,243,,0,P46196,Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2),Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2),GO:0005524; GO:0050853; GO:0038127; GO:0070371; GO:0004707; GO:0008353; GO:0050852; GO:0006915; GO:0007049; GO:0005737; GO:0019858; GO:0060716; GO:0031663; GO:0033598; GO:0005815; GO:0045596; GO:0005634; GO:0009887; GO:0018105; GO:0010800; GO:0004674; GO:0031143; GO:0006974; GO:0070849; GO:0043330; GO:0005819,ATP binding; B cell receptor signaling pathway; ERBB signaling pathway; ERK1 and ERK2 cascade; MAP kinase activity; RNA polymerase II carboxy-terminal domain kinase activity; T cell receptor signaling pathway; apoptotic process; cell cycle; cytoplasm; cytosine metabolic process; labyrinthine layer blood vessel development; lipopolysaccharide-mediated signaling pathway; mammary gland epithelial cell proliferation; microtubule organizing center; negative regulation of cell differentiation; nucleus; organ morphogenesis; peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; protein serine/threonine kinase activity; pseudopodium; response to DNA damage stimulus; response to epidermal growth factor stimulus; response to exogenous dsRNA; spindle,PF00069;,0,CHOYP_MK01.1.1,,,,,,,MK01_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; cell cycle [GO:0007049]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of protein stability [GO:0031647]; response to epidermal growth factor [GO:0070849] comp141474_c1_seq1,1736,32.7765,0.55942048,70,694,,8.00E-42,Q5R7L8,Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1),Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1),GO:0031083; GO:0009060; GO:0008089; GO:0048490; GO:0005758; GO:0005759; GO:0031175; GO:0018394,BLOC-1 complex; aerobic respiration; anterograde axon cargo transport; anterograde synaptic vesicle transport; mitochondrial intermembrane space; mitochondrial matrix; neuron projection development; peptidyl-lysine acetylation,PF06320;,2.00E-54,CHOYP_LOC100370656.3.3,,,,,,,BL1S1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),aerobic respiration [GO:0009060]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; neuron projection development [GO:0031175]; peptidyl-lysine acetylation [GO:0018394] comp141474_c1_seq2,1013,34.3534,0.54044023,29,104,,,,,,,,,1.00E-52,CHOYP_LOC100370656.3.3,,,,,,,,, comp141475_c2_seq5,306,35.6209,0.11011595,7,35,,,,,,,,,,,7.00E-16,ruditapes_c1304,,,,,,, comp141477_c2_seq1,1088,46.2316,1.05724879,226,5,,2.00E-58,P55088,Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4),Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4),GO:0030315; GO:0016323; GO:0015670; GO:0005911; GO:0071392; GO:0071346; GO:0005737; GO:0009897; GO:0007565; GO:0042538; GO:0005887; GO:0015288; GO:0043234; GO:0051260; GO:0070295; GO:0051384; GO:0009314; GO:0007605; GO:0015250,T-tubule; basolateral plasma membrane; carbon dioxide transport; cell-cell junction; cellular response to estradiol stimulus; cellular response to interferon-gamma; cytoplasm; external side of plasma membrane; female pregnancy; hyperosmotic salinity response; integral to plasma membrane; porin activity; protein complex; protein homooligomerization; renal water absorption; response to glucocorticoid stimulus; response to radiation; sensory perception of sound; water channel activity,PF00230;,8.00E-18,CHOYP_AQP4.1.3,,,,,,,AQP4_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; cellular water homeostasis [GO:0009992]; ion transmembrane transport [GO:0034220]; renal water absorption [GO:0070295]; sensory perception of sound [GO:0007605]; water homeostasis [GO:0030104]; water transport [GO:0006833] comp141477_c4_seq1,1989,38.5118,0.56364995,302,208,,0,Q6P2Y2,Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69),Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69),GO:0005929,cilium,PF00400;,0,CHOYP_BRAFLDRAFT_287844.1.1,,,,,,,WDR69_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141478_c0_seq1,2075,38.4578,0.92594173,371,1343,,7.00E-29,Q99NH0,Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein),Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein),GO:0003723; GO:0001955; GO:0005737; GO:0007492; GO:0051151; GO:0005634,RNA binding; blood vessel maturation; cytoplasm; endoderm development; negative regulation of smooth muscle cell differentiation; nucleus,PF12796;PF00013;,,,,,,,,,ANR17_MOUSE,Mus musculus (Mouse),blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] comp141480_c2_seq1,408,43.3824,0.21640342,9,11,,1.00E-16,P53071,Uncharacterized protein YGL235W,Uncharacterized protein YGL235W,,,,3.00E-50,CHOYP_MTO1.1.1,8.00E-17,ruditapes_c9459,,,,,YGY5_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp141480_c3_seq3,2162,40.9343,0.55310086,32,193,,8.00E-116,Q923Z3,"Protein MTO1 homolog, mitochondrial","Protein MTO1 homolog, mitochondrial",GO:0050660; GO:0070899; GO:0005739; GO:0055114,flavin adenine dinucleotide binding; mitochondrial tRNA wobble uridine modification; mitochondrion; oxidation-reduction process,PF01134;PF13932;,,,,,,,,,MTO1_MOUSE,Mus musculus (Mouse),mitochondrial tRNA wobble uridine modification [GO:0070899]; tRNA wobble uridine modification [GO:0002098] comp141481_c0_seq1,1947,42.0134,0.69665487,247,547,,4.00E-102,Q9NQ29,Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89),Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89),GO:0005685; GO:0003729; GO:0006376; GO:0045843,U1 snRNP; mRNA binding; mRNA splice site selection; negative regulation of striated muscle tissue development,PF03194;,5.00E-106,CHOYP_LOC100648220.1.1,,,,,,,LUC7L_HUMAN,Homo sapiens (Human),mRNA splice site selection [GO:0006376]; negative regulation of striated muscle tissue development [GO:0045843] comp141481_c0_seq2,1593,39.2969,0.55546353,50,31,,1.00E-27,Q9NQ29,Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89),Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89),GO:0005685; GO:0003729; GO:0006376; GO:0045843,U1 snRNP; mRNA binding; mRNA splice site selection; negative regulation of striated muscle tissue development,PF03194;,,,,,,,,,LUC7L_HUMAN,Homo sapiens (Human),mRNA splice site selection [GO:0006376]; negative regulation of striated muscle tissue development [GO:0045843] comp141488_c0_seq1,2328,40.1632,0.43452311,228,184,,3.00E-08,O18412,Transmembrane GTPase fzo (EC 3.6.5.-) (Protein fuzzy onions),Transmembrane GTPase fzo (EC 3.6.5.-) (Protein fuzzy onions),GO:0005525; GO:0003924; GO:0007287; GO:0016021; GO:0005740; GO:0008053; GO:0005741; GO:0007275; GO:0030382,GTP binding; GTPase activity; Nebenkern assembly; integral to membrane; mitochondrial envelope; mitochondrial fusion; mitochondrial outer membrane; multicellular organismal development; sperm mitochondrion organization,PF00350;PF04799;,,,,,,,,,FZO_DROME,Drosophila melanogaster (Fruit fly),mitochondrial fusion [GO:0008053]; mitochondrion organization [GO:0007005]; multicellular organism development [GO:0007275]; Nebenkern assembly [GO:0007287]; spermatogenesis [GO:0007283]; sperm mitochondrion organization [GO:0030382] comp141492_c0_seq1,1731,32.9289,0.56290019,40,223,,,,,,,,,4.00E-30,CHOYP_VPS25.1.1,,,,,,,,, comp141492_c0_seq2,1714,32.8471,0.57179881,36,193,,4.00E-71,Q6NWF4,Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25),Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25),GO:0005737; GO:0015031,cytoplasm; protein transport,PF05871;,3.00E-32,CHOYP_VPS25.1.1,,,,,,,VPS25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] comp141495_c0_seq1,2952,38.3469,0.41967886,2,0,,5.00E-35,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp141495_c0_seq2,3160,38.8291,0.46740246,29,12,,6.00E-35,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp141496_c1_seq3,822,48.4185,0.54342827,0,0,,8.00E-26,P21271,Unconventional myosin-Vb,Unconventional myosin-Vb,GO:0005524; GO:0003774; GO:0016459; GO:0015031,ATP binding; motor activity; myosin complex; protein transport,PF01843;PF00612;PF00063;,2.00E-156,CHOYP_MYO6.1.1,,,,,,,MYO5B_MOUSE,Mus musculus (Mouse),endosome localization [GO:0032439]; metabolic process [GO:0008152]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp141496_c1_seq4,1763,48.6103,0.57955248,8,453,,3.00E-135,Q9I8D1,Unconventional myosin-VI (Unconventional myosin-6),Unconventional myosin-VI (Unconventional myosin-6),GO:0043531; GO:0005524; GO:0030330; GO:0016591; GO:0005794; GO:0051015; GO:0030048; GO:0005516; GO:0005938; GO:0030136; GO:0030665; GO:0005905; GO:0006897; GO:0031941; GO:0030175; GO:0006886; GO:0005902; GO:0016459; GO:0031965; GO:0048471; GO:0060002; GO:0045944; GO:0051046; GO:0001726; GO:0032587; GO:0007605,"ADP binding; ATP binding; DNA damage response, signal transduction by p53 class mediator; DNA-directed RNA polymerase II, holoenzyme; Golgi apparatus; actin filament binding; actin filament-based movement; calmodulin binding; cell cortex; clathrin-coated vesicle; clathrin-coated vesicle membrane; coated pit; endocytosis; filamentous actin; filopodium; intracellular protein transport; microvillus; myosin complex; nuclear membrane; perinuclear region of cytoplasm; plus-end directed microfilament motor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of secretion; ruffle; ruffle membrane; sensory perception of sound",PF16521;PF00063;,0,CHOYP_MYO6.1.1,,,,,,,MYO6_CHICK,Gallus gallus (Chicken),"actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]" comp141497_c1_seq1,2098,41.8494,0.65697444,6,14,,2.00E-111,Q86W92,Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2),Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2),GO:0007155; GO:0005886,cell adhesion; plasma membrane,PF00536;PF07647;,9.00E-116,CHOYP_PPFIBP1.1.1,,,,,,,LIPB1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp141497_c1_seq2,2770,42.7798,0.69079284,19,44,,2.00E-40,A9C3W3,Kazrin-A,Kazrin-A,,,PF00536;PF07647;,,,,,,,,,KAZRA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141497_c1_seq3,2777,42.852,0.67082395,0,27,,6.00E-51,Q94071,Liprin-beta (LAR-interacting protein beta),Liprin-beta (LAR-interacting protein beta),GO:0016043; GO:0040017; GO:0008022; GO:0042803; GO:0043051; GO:0000003,cellular component organization; positive regulation of locomotion; protein C-terminus binding; protein homodimerization activity; regulation of pharyngeal pumping; reproduction,PF00536;PF07647;,,,,,,,,,LIPB_CAEEL,Caenorhabditis elegans,neuromuscular junction development [GO:0007528]; positive regulation of locomotion [GO:0040017]; regulation of pharyngeal pumping [GO:0043051]; reproduction [GO:0000003] comp141497_c1_seq4,811,47.5956,0.78835071,0,0,,4.00E-15,O35711,Liprin-beta-2 (Coiled-coil-like protein 1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2),Liprin-beta-2 (Coiled-coil-like protein 1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2),GO:0003677; GO:0008907,DNA binding; integrase activity,PF00536;PF07647;,,,,,,,,,LIPB2_MOUSE,Mus musculus (Mouse), comp141497_c1_seq5,804,47.3881,0.82488773,0,0,,,,,,,,,2.00E-37,CHOYP_PPFIBP1.1.1,,,,,,,,, comp141498_c0_seq10,1282,52.2621,0.76239141,0,0,,1.00E-11,A1ZA47,PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein),GO:0030018; GO:0015629; GO:0051371; GO:0005927; GO:0030239; GO:0001952; GO:0008270,Z disc; actin cytoskeleton; muscle alpha-actinin binding; muscle tendon junction; myofibril assembly; regulation of cell-matrix adhesion; zinc ion binding,PF15936;PF00412;PF00595;,,,,,,,,,ZASP_DROME,Drosophila melanogaster (Fruit fly),muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952] comp141498_c0_seq2,1378,52.3222,0.77104956,0,0,,2.00E-10,O70400,PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36),PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36),GO:0005737; GO:0005856; GO:0006355; GO:0001666; GO:0003713; GO:0005667; GO:0008270,"cytoplasm; cytoskeleton; regulation of transcription, DNA-dependent; response to hypoxia; transcription coactivator activity; transcription factor complex; zinc ion binding",PF15936;PF00412;PF00595;,,,,,,,,,PDLI1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]" comp141498_c0_seq3,1742,49.8278,0.82655078,0,0,,3.00E-11,O75112,LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein),LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein),GO:0030018; GO:0005856; GO:0048471; GO:0031143; GO:0045214; GO:0008270,Z disc; cytoskeleton; perinuclear region of cytoplasm; pseudopodium; sarcomere organization; zinc ion binding,PF15936;PF00412;PF00595;,,,,,,,,,LDB3_HUMAN,Homo sapiens (Human),sarcomere organization [GO:0045214] comp141498_c0_seq8,2529,44.3258,0.83003676,0,29,,4.00E-10,O70400,PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36),PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36),GO:0005737; GO:0005856; GO:0006355; GO:0001666; GO:0003713; GO:0005667; GO:0008270,"cytoplasm; cytoskeleton; regulation of transcription, DNA-dependent; response to hypoxia; transcription coactivator activity; transcription factor complex; zinc ion binding",PF15936;PF00412;PF00595;,,,,,,,,,PDLI1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]" comp141498_c0_seq9,1643,49.6044,0.86498091,0,0,,,,,,,,,,,1.00E-21,ruditapes2_c145,,,,,,, comp141499_c4_seq1,2594,39.2059,0.88322672,72,995,,9.00E-14,P76482,Uncharacterized protein YfbL,Uncharacterized protein YfbL,GO:0016021; GO:0008233; GO:0006508,integral to membrane; peptidase activity; proteolysis,PF04389;,,,,,,,,,YFBL_ECOLI,Escherichia coli (strain K12), comp141499_c4_seq6,1161,44.6167,0.81419921,0,0,,5.00E-09,P25152,Aminopeptidase YwaD (Arginyl aminopeptidase) (EC 3.4.11.6) (BSAP) (Leucyl aminopeptidase) (EC 3.4.11.10),Aminopeptidase YwaD (Arginyl aminopeptidase) (EC 3.4.11.6) (BSAP) (Leucyl aminopeptidase) (EC 3.4.11.10),GO:0004177; GO:0005576; GO:0046872; GO:0008237; GO:0006508,aminopeptidase activity; extracellular region; metal ion binding; metallopeptidase activity; proteolysis,PF02225;PF04389;,,,,,,,,,BSAP_BACSU,Bacillus subtilis (strain 168), comp141500_c0_seq1,375,40.5333,0.46216308,4,112,,7.00E-06,Q8N9V6,Ankyrin repeat domain-containing protein 53,Ankyrin repeat domain-containing protein 53,,,PF12796;,,,,,,,,,ANR53_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic cytokinesis [GO:1902412]; regulation of mitotic spindle organization [GO:0060236] comp141500_c1_seq1,1415,41.3428,0.46357856,143,638,,1.00E-08,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,2.00E-15,CHOYP_CRE_19274.1.1,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp141501_c0_seq4,1967,37.0615,0.53547796,5,20,,1.00E-40,Q9DCW2,Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2),Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2),GO:0071222; GO:0005737; GO:0016021; GO:0046872; GO:0005634,cellular response to lipopolysaccharide; cytoplasm; integral to membrane; metal ion binding; nucleus,PF03803;,,,,,,,,,PLS2_MOUSE,Mus musculus (Mouse),cellular response to lipopolysaccharide [GO:0071222] comp141504_c0_seq1,1943,40.4014,0.47444045,12,38,,0,Q8JZN5,"Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)","Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)",GO:0003995; GO:0030425; GO:0050660; GO:0005739; GO:0005634,acyl-CoA dehydrogenase activity; dendrite; flavin adenine dinucleotide binding; mitochondrion; nucleus,PF00441;PF02770;PF02771;,,,,,,,,,ACAD9_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; mitochondrial respiratory chain complex I assembly [GO:0032981] comp141504_c0_seq2,2491,40.8671,0.51603282,54,67,,0,Q8JZN5,"Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)","Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)",GO:0003995; GO:0030425; GO:0050660; GO:0005739; GO:0005634,acyl-CoA dehydrogenase activity; dendrite; flavin adenine dinucleotide binding; mitochondrion; nucleus,PF00441;PF02770;PF02771;,2.00E-174,CHOYP_LOC753939.1.1,,,,,,,ACAD9_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; mitochondrial respiratory chain complex I assembly [GO:0032981] comp141506_c0_seq1,738,38.8889,0.54178985,39,48,,1.00E-28,Q96Q15,Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (61E3.4) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein),Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (61E3.4) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein),GO:0005524; GO:0006281; GO:0005829; GO:0010467; GO:0006406; GO:0046872; GO:0000184; GO:0005634; GO:0018105; GO:0046854; GO:0046777; GO:0004674; GO:0006950,"ATP binding; DNA repair; cytosol; gene expression; mRNA export from nucleus; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; phosphatidylinositol phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity; response to stress",PF02260;PF00454;PF15785;,,,,,,,,,SMG1_HUMAN,Homo sapiens (Human),"DNA repair [GO:0006281]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; response to stress [GO:0006950]; telomere maintenance [GO:0000723]" comp141508_c0_seq1,2432,40.6661,0.31252025,482,2581,,6.00E-62,Q6DCP5,Protein saal1,Protein saal1,GO:0006953; GO:0005576,acute-phase response; extracellular region,,4.00E-57,CHOYP_LOC100718468.1.1,,,,,,,SAAL1_XENLA,Xenopus laevis (African clawed frog), comp141509_c1_seq1,3267,42.9446,0.53980184,25,11,,1.00E-139,Q9VN14,Contactin,Contactin,GO:0031225; GO:0008366; GO:0030246; GO:0061343; GO:0060857; GO:0045197; GO:0021682; GO:0005886; GO:0005918; GO:0019991,anchored to membrane; axon ensheathment; carbohydrate binding; cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; establishment or maintenance of epithelial cell apical/basal polarity; nerve maturation; plasma membrane; septate junction; septate junction assembly,PF00041;PF00047;PF00059;,,,,,,,,,CONT_DROME,Drosophila melanogaster (Fruit fly),axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] comp141509_c1_seq3,2834,43.6838,0.54185787,8,3,,4.00E-135,Q62682,Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1),Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1),GO:0046658; GO:0016337; GO:0007399,anchored to plasma membrane; cell-cell adhesion; nervous system development,PF00041;PF07679;,,,,,,,,,CNTN3_RAT,Rattus norvegicus (Rat),nervous system development [GO:0007399]; single organismal cell-cell adhesion [GO:0016337] comp141510_c1_seq1,1092,40.1099,0.86905831,149,681,,1.00E-07,Q8R066,Complement C1q tumor necrosis factor-related protein 4,Complement C1q tumor necrosis factor-related protein 4,GO:0005615,extracellular space,PF00386;,,,,,,,,,C1QT4_MOUSE,Mus musculus (Mouse), comp141511_c0_seq1,2677,33.0594,0.30153649,40450,3609,,8.00E-54,O96860,"Dynein light chain 2, cytoplasmic (8 kDa dynein light chain)","Dynein light chain 2, cytoplasmic (8 kDa dynein light chain)",GO:0042623; GO:0005737; GO:0030286; GO:0005874; GO:0007018; GO:0003774,"ATPase activity, coupled; cytoplasm; dynein complex; microtubule; microtubule-based movement; motor activity",PF01221;,4.00E-71,CHOYP_DYL2.2.3,1.00E-81,ruditapes2_c439,,,,,DYL2_DROME,Drosophila melanogaster (Fruit fly),microtubule-based movement [GO:0007018] comp141512_c1_seq1,2116,43.1002,0.24259264,99,683,,0,Q6NV04,Acetolactate synthase-like protein (EC 2.2.1.-) (IlvB-like protein),Acetolactate synthase-like protein (EC 2.2.1.-) (IlvB-like protein),GO:0016021; GO:0000287; GO:0008152; GO:0030976; GO:0016740,integral to membrane; magnesium ion binding; metabolic process; thiamine pyrophosphate binding; transferase activity,PF02775;PF00205;PF02776;,0,CHOYP_ILVBL.1.1,,,,,,,ILVBL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic cranial skeleton morphogenesis [GO:0048701] comp141512_c2_seq1,2135,37.4239,0.4743054,6,14,,2.00E-08,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141512_c2_seq3,1403,39.0592,0.58676691,41,44,,7.00E-12,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141512_c3_seq3,599,35.2254,1.56334668,0,0,,,,,,,,,,,2.00E-20,ruditapes2_c1084,,,,,,, comp141514_c2_seq1,3081,38.9809,1.10412165,0,0,,1.00E-106,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,3.00E-180,CHOYP_DERE_GG18317.1.1,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp141514_c2_seq2,3054,38.9653,1.0973671,0,0,,1.00E-88,P19367,Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I),Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I),GO:0005524; GO:0008219; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0015758; GO:0006096; GO:0019158; GO:0045121; GO:0005741; GO:0005739; GO:0005634; GO:0044281; GO:0055085,ATP binding; cell death; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glucose transport; glycolysis; mannokinase activity; membrane raft; mitochondrial outer membrane; mitochondrion; nucleus; small molecule metabolic process; transmembrane transport,PF00349;PF03727;,,,,,,,,,HXK1_HUMAN,Homo sapiens (Human),canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; glucose transport [GO:0015758]; glycolytic process [GO:0006096]; maintenance of protein location in mitochondrion [GO:0072656] comp141514_c2_seq3,3069,39.0029,1.0979045,18,24,,4.00E-89,Q91W97,Putative hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1),Putative hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158; GO:0005739; GO:0005634,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity; mitochondrion; nucleus,PF00349;PF03727;,,,,,,,,,HKDC1_MOUSE,Mus musculus (Mouse),cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318] comp141514_c2_seq5,3042,39.0204,1.08939415,25,9,,8.00E-107,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,3.00E-180,CHOYP_DERE_GG18317.1.1,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp141516_c0_seq2,1354,27.9173,0.34235442,119,239,,1.00E-17,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,2.00E-13,CHOYP_contig_026738,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp141518_c0_seq1,1075,44.5581,0.17240535,0,0,,2.00E-33,P78568,Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase),Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase),GO:0003842; GO:0005737; GO:0016620; GO:0006561; GO:0010133,"1-pyrroline-5-carboxylate dehydrogenase activity; cytoplasm; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; proline biosynthetic process; proline catabolic process to glutamate",PF00171;,,,,,,,,,PUT2_AGABI,Agaricus bisporus (White button mushroom),glutamate biosynthetic process [GO:0006537]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133] comp141518_c0_seq2,1688,39.5142,0.20243217,0,0,,0,Q3SY69,Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2),Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2),GO:0009258; GO:0009058; GO:0016155; GO:0016742; GO:0032259; GO:0008168; GO:0005739; GO:0006730; GO:0016620,"10-formyltetrahydrofolate catabolic process; biosynthetic process; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; methylation; methyltransferase activity; mitochondrion; one-carbon metabolic process; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",PF00171;PF02911;PF00551;PF00550;,,,,,,,,,AL1L2_HUMAN,Homo sapiens (Human),10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730] comp141518_c0_seq3,1066,47.1857,0.46368945,0,0,,2.00E-37,Q67PR4,Methionyl-tRNA formyltransferase (EC 2.1.2.9),Methionyl-tRNA formyltransferase (EC 2.1.2.9),GO:0004479; GO:0006413,methionyl-tRNA formyltransferase activity; translational initiation,PF02911;PF00551;,,,,,,,,,FMT_SYMTH,Symbiobacterium thermophilum (strain T / IAM 14863), comp141518_c0_seq4,2769,44.8537,0.31658662,0,0,,7.00E-40,A8FRE9,N-succinylglutamate 5-semialdehyde dehydrogenase (EC 1.2.1.71) (Succinylglutamic semialdehyde dehydrogenase) (SGSD),N-succinylglutamate 5-semialdehyde dehydrogenase (EC 1.2.1.71) (Succinylglutamic semialdehyde dehydrogenase) (SGSD),GO:0019544; GO:0019545; GO:0043824,arginine catabolic process to glutamate; arginine catabolic process to succinate; succinylglutamate-semialdehyde dehydrogenase activity,PF00171;,0,CHOYP_LOC100377034.1.1,,,,,,,ASTD_SHESH,Shewanella sediminis (strain HAW-EB3),arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545] comp141518_c0_seq5,3382,42.2827,0.31927914,0,0,,0,Q6GNL7,Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1),Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1),GO:0009258; GO:0009058; GO:0005737; GO:0016155; GO:0016742; GO:0032259; GO:0008168; GO:0006730; GO:0016620,"10-formyltetrahydrofolate catabolic process; biosynthetic process; cytoplasm; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; methylation; methyltransferase activity; one-carbon metabolic process; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",PF00171;PF02911;PF00551;,0,CHOYP_LOC100377034.1.1,,,,,,,AL1L1_XENLA,Xenopus laevis (African clawed frog),10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; one-carbon metabolic process [GO:0006730] comp141518_c2_seq1,685,39.4161,0.30114199,0,0,,4.00E-21,B1HTI6,Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS),Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS),GO:0005524; GO:0005737; GO:0004820; GO:0006426; GO:0046983,ATP binding; cytoplasm; glycine-tRNA ligase activity; glycyl-tRNA aminoacylation; protein dimerization activity,PF03129;PF00587;,,,,,,,,,SYG_LYSSC,Lysinibacillus sphaericus (strain C3-41),glycyl-tRNA aminoacylation [GO:0006426] comp141518_c2_seq2,1516,38.9842,0.39966799,43,294,,9.00E-39,Q9W6G7,"DNA polymerase subunit gamma-2, mitochondrial (EC 2.7.7.7) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta)","DNA polymerase subunit gamma-2, mitochondrial (EC 2.7.7.7) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta)",GO:0003677; GO:0006281; GO:0006260; GO:0003887; GO:0005739,DNA binding; DNA repair; DNA replication; DNA-directed DNA polymerase activity; mitochondrion,PF03129;,,,,,,,,,DPOG2_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; DNA replication [GO:0006260] comp141519_c2_seq1,1916,40.2401,0.41280192,69,151,,3.00E-26,Q61493,DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0005694; GO:0046872; GO:0000166; GO:0005634; GO:0019985; GO:0016035,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; chromosome; metal ion binding; nucleotide binding; nucleus; translesion synthesis; zeta DNA polymerase complex",PF00136;PF03104;PF15735;PF14260;,2.00E-27,CHOYP_DPOLZ.1.1,,,,,,,DPOLZ_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276] comp141519_c3_seq1,364,46.7033,0.45777937,9,5,,6.00E-07,P14284,DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3),DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0070987; GO:0042276; GO:0046872; GO:0005739; GO:0000166; GO:0005634; GO:0016035,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; error-free translesion synthesis; error-prone translesion synthesis; metal ion binding; mitochondrion; nucleotide binding; nucleus; zeta DNA polymerase complex",PF00136;PF03104;PF14260;,,,,,,,,,DPOZ_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276] comp141520_c0_seq1,1829,41.17,0.31861652,129,296,,3.00E-157,Q3MI03,2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 (EC 1.14.11.-),Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1),GO:0031418; GO:0005737; GO:0005506; GO:0005634; GO:0016706,"L-ascorbic acid binding; cytoplasm; iron ion binding; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF10637;,6.00E-22,CHOYP_OGFD1.1.1,,,,,,,OGFD1_BOVIN,Bos taurus (Bovine),cell proliferation [GO:0008283]; protein hydroxylation [GO:0018126]; regulation of translational termination [GO:0006449]; stress granule assembly [GO:0034063] comp141521_c0_seq1,936,32.4786,0.91504011,62,235,,5.00E-27,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,1.00E-43,ruditapes_c12969,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141522_c0_seq2,1847,37.2496,0.42631591,149,278,,0,Q5R613,"Sorting nexin-6 [Cleaved into: Sorting nexin-6, N-terminally processed]","Sorting nexin-6 [Cleaved into: Sorting nexin-6, N-terminally processed]",GO:0007154; GO:0030659; GO:0031901; GO:0006886; GO:0005634; GO:0035091; GO:0042147,"cell communication; cytoplasmic vesicle membrane; early endosome membrane; intracellular protein transport; nucleus; phosphatidylinositol binding; retrograde transport, endosome to Golgi",PF00787;PF09325;,0,CHOYP_BRAFLDRAFT_77132.1.2,,,,,,,SNX6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]" comp141523_c0_seq1,1334,37.8561,0.3443275,46,97,,2.00E-38,Q5RET3,Alpha- and gamma-adaptin-binding protein p34,Alpha- and gamma-adaptin-binding protein p34,GO:0005829; GO:0015031,cytosol; protein transport,PF10199;,3.00E-11,CHOYP_LOC100653683.1.1,,,,,,,AAGAB_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp141523_c0_seq2,1413,36.8719,0.3153436,0,24,,1.00E-35,Q8R2R3,Alpha- and gamma-adaptin-binding protein p34,Alpha- and gamma-adaptin-binding protein p34,GO:0005829; GO:0015031,cytosol; protein transport,PF10199;,,,,,,,,,AAGAB_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp141526_c0_seq1,591,37.3942,0.63498532,82,271,,,,,,,,,7.00E-22,CHOYP_ZCRB1.1.1,,,,,,,,, comp141526_c3_seq1,424,39.1509,0.43698833,33,204,,1.00E-48,Q56JZ7,Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein),Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein),GO:0003723; GO:0008380; GO:0005689; GO:0006397; GO:0005654; GO:0000166; GO:0008270,RNA binding; RNA splicing; U12-type spliceosomal complex; mRNA processing; nucleoplasm; nucleotide binding; zinc ion binding,PF00076;PF00098;,2.00E-21,CHOYP_ZCRB1.1.1,,,,,,,ZCRB1_BOVIN,Bos taurus (Bovine),"mRNA splicing, via spliceosome [GO:0000398]" comp141527_c4_seq1,3419,40.6552,0.37537202,223,1211,,1.00E-90,Q04206,Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3),Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3),GO:0038095; GO:0002755; GO:0003705; GO:0050852; GO:0035666; GO:0006117; GO:0007568; GO:0006968; GO:0071347; GO:0071222; GO:0071356; GO:0003682; GO:0019221; GO:0005829; GO:0051607; GO:0001942; GO:0042802; GO:0006954; GO:0045087; GO:0001889; GO:0031293; GO:0019048; GO:0043066; GO:2001237; GO:0046627; GO:0042177; GO:0045892; GO:0048011; GO:0005654; GO:0070431; GO:0009887; GO:0042301; GO:0043123; GO:0051092; GO:0014040; GO:0008284; GO:0032332; GO:0045084; GO:0045944; GO:0032481; GO:0050727; GO:0010224; GO:0043200; GO:0051591; GO:0033590; GO:0042493; GO:0042542; GO:0032868; GO:0009612; GO:0043278; GO:0032495; GO:0032570; GO:0043565; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124; GO:0005667; GO:0044212,"Fc-epsilon receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; T cell receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; acetaldehyde metabolic process; aging; cellular defense response; cellular response to interleukin-1; cellular response to lipopolysaccharide; cellular response to tumor necrosis factor; chromatin binding; cytokine-mediated signaling pathway; cytosol; defense response to virus; hair follicle development; identical protein binding; inflammatory response; innate immune response; liver development; membrane protein intracellular domain proteolysis; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of insulin receptor signaling pathway; negative regulation of protein catabolic process; negative regulation of transcription, DNA-dependent; neurotrophin TRK receptor signaling pathway; nucleoplasm; nucleotide-binding oligomerization domain containing 2 signaling pathway; organ morphogenesis; phosphate ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of Schwann cell differentiation; positive regulation of cell proliferation; positive regulation of chondrocyte differentiation; positive regulation of interleukin-12 biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type I interferon production; regulation of inflammatory response; response to UV-B; response to amino acid stimulus; response to cAMP; response to cobalamin; response to drug; response to hydrogen peroxide; response to insulin stimulus; response to mechanical stimulus; response to morphine; response to muramyl dipeptide; response to progesterone stimulus; sequence-specific DNA binding; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway; transcription factor complex; transcription regulatory region DNA binding",PF16179;PF00554;,,,,,,,,,TF65_HUMAN,Homo sapiens (Human),"acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; cellular defense response [GO:0006968]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; Fc-epsilon receptor signaling pathway [GO:0038095]; hair follicle development [GO:0001942]; inflammatory response [GO:0006954]; liver development [GO:0001889]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; organ morphogenesis [GO:0009887]; positive regulation of cell proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of inflammatory response [GO:0050727]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to drug [GO:0042493]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]" comp141527_c4_seq2,1455,43.5739,0.4804562,0,11,,3.00E-105,P15330,Embryonic polarity protein dorsal,Embryonic polarity protein dorsal,GO:0001077; GO:0000977; GO:0008063; GO:0009952; GO:0005737; GO:0009950; GO:0001715; GO:0010004; GO:0008354; GO:0007507; GO:0035006; GO:0007501; GO:0000122; GO:0031594; GO:0005634; GO:0048935; GO:0042387; GO:0006964; GO:0000381; GO:0035206; GO:0007419,"RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II regulatory region sequence-specific DNA binding; Toll signaling pathway; anterior/posterior pattern specification; cytoplasm; dorsal/ventral axis specification; ectodermal cell fate specification; gastrulation involving germ band extension; germ cell migration; heart development; melanization defense response; mesodermal cell fate specification; negative regulation of transcription from RNA polymerase II promoter; neuromuscular junction; nucleus; peripheral nervous system neuron development; plasmatocyte differentiation; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; regulation of alternative mRNA splicing, via spliceosome; regulation of hemocyte proliferation; ventral cord development",PF16179;PF00554;,2.00E-109,CHOYP_DWIL_GK10525.1.1,,,,,,,DORS_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior pattern specification [GO:0009952]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectodermal cell fate specification [GO:0001715]; ectoderm development [GO:0007398]; gastrulation [GO:0007369]; gastrulation involving germ band extension [GO:0010004]; germ cell migration [GO:0008354]; heart development [GO:0007507]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; maternal determination of anterior/posterior axis, embryo [GO:0008358]; melanization defense response [GO:0035006]; mesodermal cell fate specification [GO:0007501]; mesoderm development [GO:0007498]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; peripheral nervous system neuron development [GO:0048935]; plasmatocyte differentiation [GO:0042387]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; Toll signaling pathway [GO:0008063]; ventral cord development [GO:0007419]" comp141531_c0_seq2,3283,42.0956,0.3323943,20,259,,2.00E-85,Q9BRR8,G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein),G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein),GO:0071013; GO:0000398; GO:0003676,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleic acid binding",PF07713;PF01585;,2.00E-32,CHOYP_GPTC1.1.1,,,,,,,GPTC1_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]" comp141533_c1_seq3,2619,35.8916,0.56215227,26,28,,4.00E-55,Q7SXL7,Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (WT1-associated protein) (Wilms tumor 1-associating protein),Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (WT1-associated protein) (Wilms tumor 1-associating protein),GO:0008380; GO:0007049; GO:0006397; GO:0005730,RNA splicing; cell cycle; mRNA processing; nucleolus,PF17098;,6.00E-81,CHOYP_LOC100121674.1.1,,,,,,,FL2D_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell cycle [GO:0007049]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]" comp141534_c3_seq2,4315,33.0939,0.42556383,18,0,,8.00E-09,Q9QX82,Sialomucin core protein 24 (MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v),Sialomucin core protein 24 (MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v),GO:0005768; GO:0010008; GO:0007157; GO:0016021; GO:0005765; GO:0005764; GO:0007517; GO:0005886,endosome; endosome membrane; heterophilic cell-cell adhesion; integral to membrane; lysosomal membrane; lysosome; muscle organ development; plasma membrane,PF05283;,,,,,,,,,MUC24_RAT,Rattus norvegicus (Rat),heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; muscle organ development [GO:0007517] comp141536_c0_seq1,1540,37.8571,0.44381529,6,11,,2.00E-29,Q09699,SWI/SNF chromatin-remodeling complex subunit snf5 (SWI/SNF complex subunit snf5),SWI/SNF chromatin-remodeling complex subunit snf5 (SWI/SNF complex subunit snf5),GO:0005794; GO:0016514; GO:0006338; GO:0000991; GO:0010972; GO:0000122; GO:0000790; GO:0010811; GO:0045944; GO:1900389; GO:1900400,Golgi apparatus; SWI/SNF complex; chromatin remodeling; core RNA polymerase II binding transcription factor activity; negative regulation of G2/M transition of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; positive regulation of cell-substrate adhesion; positive regulation of transcription from RNA polymerase II promoter; regulation of glucose import by regulation of transcription from RNA polymerase II promoter; regulation of iron ion import by regulation of transcription from RNA polymerase II promoter,PF04855;,,,,,,,,,SNF5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; nucleosome disassembly [GO:0006337]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of iron ion import by regulation of transcription from RNA polymerase II promoter [GO:1900400]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp141536_c0_seq2,2028,39.497,0.53919076,23,154,,2.00E-18,Q6CSR7,Chromatin structure-remodeling complex subunit SFH1 (RSC complex subunit SFH1) (SNF5 homolog 1),Chromatin structure-remodeling complex subunit SFH1 (RSC complex subunit SFH1) (SNF5 homolog 1),GO:0007049; GO:0006338; GO:0000228; GO:0006355; GO:0006351,"cell cycle; chromatin remodeling; nuclear chromosome; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04855;,,,,,,,,,SFH1_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),"ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling at centromere [GO:0031055]; chromosome segregation [GO:0007059]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleosome disassembly [GO:0006337]; regulation of nuclear cell cycle DNA replication [GO:0033262]; regulation of transcription, DNA-templated [GO:0006355]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp141536_c0_seq3,1994,39.4684,0.52203962,0,56,,0,Q6GQ82,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,GO:0006338; GO:0007399; GO:0000228; GO:0006355; GO:0006351,"chromatin remodeling; nervous system development; nuclear chromosome; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04855;,5.00E-125,CHOYP_EF-1A.9.9,2.00E-25,ruditapes_c12190,,,,,SNF5_XENLA,Xenopus laevis (African clawed frog),"chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141541_c0_seq1,2702,40.5625,0.47166449,846,2599,,0,Q8BKT7,THO complex subunit 5 homolog (Fms-interacting protein),THO complex subunit 5 homolog (Fms-interacting protein) (FMIP),GO:0003723; GO:0008380; GO:0000445; GO:0005737; GO:0045111; GO:0046784; GO:0006397; GO:0030224; GO:0045650; GO:0060215,RNA binding; RNA splicing; THO complex part of transcription export complex; cytoplasm; intermediate filament cytoskeleton; intronless viral mRNA export from host nucleus; mRNA processing; monocyte differentiation; negative regulation of macrophage differentiation; primitive hemopoiesis,PF09766;,6.00E-69,CHOYP_THOC5.1.1,2.00E-41,ruditapes2_c3010,,,,,THOC5_MOUSE,Mus musculus (Mouse),"blastocyst development [GO:0001824]; cell morphogenesis [GO:0000902]; monocyte differentiation [GO:0030224]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of macrophage differentiation [GO:0045650]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; primitive hemopoiesis [GO:0060215]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; regulation of stem cell division [GO:2000035]; RNA splicing [GO:0008380]; stem cell division [GO:0017145]; viral mRNA export from host cell nucleus [GO:0046784]" comp141542_c0_seq1,1976,39.3219,0.59631749,262,2104,,7.00E-160,Q9CQS5,Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2),Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF09202;,1.00E-125,CHOYP_RIOK2.1.1,,,,,,,RIOK2_MOUSE,Mus musculus (Mouse), comp141543_c0_seq3,4349,36.882,0.42290759,328,424,,,,,,,,,9.00E-12,CHOYP_contig_031485,2.00E-18,ruditapes_c20225,,,,,,, comp141543_c2_seq1,787,44.5997,0.87298935,74,15,,,,,,,,,,,7.00E-59,ruditapes_c15188,,,,,,, comp141546_c0_seq3,1019,41.8057,0.90319526,13,92,,7.00E-06,P18503,Short-chain collagen C4 (Fragment),Short-chain collagen C4 (Fragment),GO:0005581,collagen,PF01391;,,,,,,,,,CAS4_EPHMU,Ephydatia muelleri (Mueller's freshwater sponge), comp141546_c0_seq7,1025,39.4146,0.81926466,8,81,,,,,,,,,2.00E-13,CHOYP_BRAFLDRAFT_76550.1.21,,,,,,,,, comp141550_c0_seq1,2404,39.0599,0.45157088,27184,72721,,0,P17244,Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-),Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-),GO:0051287; GO:0050661; GO:0005829; GO:0004365; GO:0006096; GO:0008017; GO:0015630; GO:0000226; GO:0051402; GO:0005634; GO:0035605; GO:0035606; GO:0050821; GO:0006417,NAD binding; NADP binding; cytosol; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; glycolysis; microtubule binding; microtubule cytoskeleton; microtubule cytoskeleton organization; neuron apoptotic process; nucleus; peptidyl-cysteine S-nitrosylase activity; peptidyl-cysteine S-trans-nitrosylation; protein stabilization; regulation of translation,PF02800;PF00044;,4.00E-152,CHOYP_TRIADDRAFT_63204.1.2,2.00E-96,ruditapes_c8255,,,,,G3P_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417] comp141551_c0_seq2,3320,46.9578,0.51408673,146,111,,0,Q9VDY1,Putative DNA helicase Ino80 (dINO80) (EC 3.6.4.12),Putative DNA helicase Ino80 (dINO80) (EC 3.6.4.12),GO:0005524; GO:0016887; GO:0003678; GO:0006310; GO:0006281; GO:0031011; GO:0006338; GO:0005700; GO:0010468; GO:0006355; GO:0000975; GO:0006351,"ATP binding; ATPase activity; DNA helicase activity; DNA recombination; DNA repair; Ino80 complex; chromatin remodeling; polytene chromosome; regulation of gene expression; regulation of transcription, DNA-dependent; regulatory region DNA binding; transcription, DNA-dependent",PF13892;PF00271;PF00176;,1.00E-15,CHOYP_SMARCA5.1.1,,,,,,,INO80_DROME,Drosophila melanogaster (Fruit fly),"chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of development, heterochronic [GO:0040034]; regulation of gene expression [GO:0010468]; transcription, DNA-templated [GO:0006351]" comp141551_c0_seq3,1329,46.6516,0.54328389,0,0,,0,Q6ZPV2,DNA helicase INO80 (EC 3.6.4.12) (INO80 complex subunit A) (Putative DNA helicase INO80 complex homolog 1),DNA helicase INO80 (EC 3.6.4.12) (INO80 complex subunit A) (Putative DNA helicase INO80 complex homolog 1),GO:0005524; GO:0016887; GO:0003677; GO:0003678; GO:0031011; GO:0070914; GO:0051301; GO:0034644; GO:0071479; GO:0006338; GO:0000724; GO:0005874; GO:0000070; GO:0005634; GO:0030307; GO:0010571; GO:0045944; GO:2000045; GO:0051225,ATP binding; ATPase activity; DNA binding; DNA helicase activity; Ino80 complex; UV-damage excision repair; cell division; cellular response to UV; cellular response to ionizing radiation; chromatin remodeling; double-strand break repair via homologous recombination; microtubule; mitotic sister chromatid segregation; nucleus; positive regulation of cell growth; positive regulation of nuclear cell cycle DNA replication; positive regulation of transcription from RNA polymerase II promoter; regulation of G1/S transition of mitotic cell cycle; spindle assembly,PF13892;PF00271;PF00176;,0,CHOYP_INO80.1.2,,,,,,,INO80_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of cell growth [GO:0030307]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; spindle assembly [GO:0051225]; transcription, DNA-templated [GO:0006351]; UV-damage excision repair [GO:0070914]" comp141551_c0_seq4,761,48.0946,0.4173571,0,0,,,,,,,,,2.00E-92,CHOYP_INO80.2.2,,,,,,,,, comp141552_c0_seq1,1459,38.5195,0.53632301,165,334,,4.00E-07,Q5XLR4,Borealin (Cell division cycle-associated protein 8) (Dasra-B) (DasraB) (DrDasraB),Borealin (Cell division cycle-associated protein 8) (Dasra-B) (DasraB) (DrDasraB),GO:0051301; GO:0032133; GO:0000775; GO:0005737; GO:0007507; GO:0007067; GO:0005634; GO:0005819,"cell division; chromosome passenger complex; chromosome, centromeric region; cytoplasm; heart development; mitosis; nucleus; spindle",PF10512;PF10444;,,,,,,,,,BORE1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; heart development [GO:0007507]; mitotic sister chromatid segregation [GO:0000070] comp141553_c2_seq3,1224,34.8856,0.56548442,0,94,,,,,,,,,5.00E-21,CHOYP_BRAFLDRAFT_127523.1.1,5.00E-57,ruditapes_c11068,,,,,,, comp141553_c2_seq4,1204,35.1329,0.48658504,24,109,,1.00E-26,Q5RF96,Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit),Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit),GO:0030176; GO:0008233; GO:0006508; GO:0043022; GO:0005787; GO:0006465,integral to endoplasmic reticulum membrane; peptidase activity; proteolysis; ribosome binding; signal peptidase complex; signal peptide processing,PF06645;,,,,,,,,,SPCS1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),signal peptide processing [GO:0006465] comp141553_c2_seq6,1207,34.797,0.5218858,0,0,,1.00E-16,Q61CQ8,Probable signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit),Probable signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit),GO:0016021; GO:0008233; GO:0006508; GO:0005787; GO:0006465,integral to membrane; peptidase activity; proteolysis; signal peptidase complex; signal peptide processing,PF06645;,,,,,,,,,SPCS1_CAEBR,Caenorhabditis briggsae,protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465] comp141553_c2_seq9,1187,35.0463,0.46863939,12,0,,1.00E-26,Q5RF96,Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit),Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit),GO:0030176; GO:0008233; GO:0006508; GO:0043022; GO:0005787; GO:0006465,integral to endoplasmic reticulum membrane; peptidase activity; proteolysis; ribosome binding; signal peptidase complex; signal peptide processing,PF06645;,,,,,,,,,SPCS1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),signal peptide processing [GO:0006465] comp141555_c2_seq1,1271,47.915,0.87362691,132,1057,,7.00E-63,O43315,Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1),Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1),GO:0005275; GO:0016323; GO:0015722; GO:0046943; GO:0071320; GO:0007588; GO:0015254; GO:0006955; GO:0005887; GO:0043231; GO:0008152; GO:0015288; GO:0005345; GO:0005350; GO:0046689; GO:0006970; GO:0015250; GO:0030104,amine transmembrane transporter activity; basolateral plasma membrane; canalicular bile acid transport; carboxylic acid transmembrane transporter activity; cellular response to cAMP; excretion; glycerol channel activity; immune response; integral to plasma membrane; intracellular membrane-bounded organelle; metabolic process; porin activity; purine nucleobase transmembrane transporter activity; pyrimidine nucleobase transmembrane transporter activity; response to mercury ion; response to osmotic stress; water channel activity; water homeostasis,PF00230;,4.00E-35,CHOYP_LOC100373328.1.1,,,,,,,AQP9_HUMAN,Homo sapiens (Human),amine transport [GO:0015837]; canalicular bile acid transport [GO:0015722]; carboxylic acid transport [GO:0046942]; cellular response to cAMP [GO:0071320]; cellular water homeostasis [GO:0009992]; excretion [GO:0007588]; glycerol transport [GO:0015793]; immune response [GO:0006955]; metabolic process [GO:0008152]; polyol transport [GO:0015791]; purine nucleobase transport [GO:0006863]; pyrimidine nucleobase transport [GO:0015855]; response to mercury ion [GO:0046689]; response to organic substance [GO:0010033]; response to osmotic stress [GO:0006970]; transport [GO:0006810]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104]; water transport [GO:0006833] comp141558_c0_seq1,2484,42.7536,1.13390651,23,74,,2.00E-10,A6QR55,Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),GO:0005737; GO:0046872; GO:0031397; GO:0005634; GO:0016579; GO:0034394; GO:0031647; GO:0004221; GO:0006511; GO:0004843,cytoplasm; metal ion binding; negative regulation of protein ubiquitination; nucleus; protein deubiquitination; protein localization to cell surface; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;,,,7.00E-97,ruditapes_c23765,,,,,UBP4_BOVIN,Bos taurus (Bovine),negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141558_c0_seq2,1508,41.3793,1.10317288,0,21,,2.00E-23,Q9SE95,FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000),FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000),GO:0051260; GO:0016567,protein homooligomerization; protein ubiquitination,PF02214;PF00805;,,,5.00E-58,ruditapes_c1373,,,,,FIP2_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] comp141558_c0_seq3,2501,42.8629,1.13727291,53,327,,2.00E-10,A6QR55,Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),GO:0005737; GO:0046872; GO:0031397; GO:0005634; GO:0016579; GO:0034394; GO:0031647; GO:0004221; GO:0006511; GO:0004843,cytoplasm; metal ion binding; negative regulation of protein ubiquitination; nucleus; protein deubiquitination; protein localization to cell surface; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;,4.00E-45,CHOYP_LOC100377510.1.4,,,,,,,UBP4_BOVIN,Bos taurus (Bovine),negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141558_c0_seq4,1525,41.4426,1.10278977,0,0,,2.00E-23,Q9SE95,FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000),FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000),GO:0051260; GO:0016567,protein homooligomerization; protein ubiquitination,PF02214;PF00805;,,,1.00E-77,ruditapes_c353,,,,,FIP2_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] comp141559_c2_seq1,2380,39.3277,0.6316691,208,560,,7.00E-27,Q9UJU3,Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228),Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZF112_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141559_c2_seq2,1112,36.8705,0.77217766,3,0,,3.00E-07,O96785,Protein hunchback (Fragment),Protein hunchback (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0040034; GO:0035282; GO:0000981; GO:0006366,"DNA binding; metal ion binding; nucleus; regulation of development, heterochronic; segmentation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter",,,,,,,,,,HUNB_CLOAL,Clogmia albipunctata (Mothmidge),"regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]" comp141560_c1_seq1,3478,46.4635,0.48354147,156,0,,3.00E-161,Q96N23,Uncharacterized protein C12orf55,Cilia- and flagella-associated protein 54,,,PF14858;,0,CHOYP_BRAFLDRAFT_125670.1.1,,,,,,,CL055_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; spermatogenesis [GO:0007283] comp141560_c1_seq2,2184,46.978,0.48674922,25,0,,3.00E-62,Q96N23,Uncharacterized protein C12orf55,Cilia- and flagella-associated protein 54,,,PF14858;,3.00E-52,CHOYP_LOC575277.1.2,,,,,,,CL055_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; spermatogenesis [GO:0007283] comp141560_c1_seq7,563,46.5364,0.32959431,18,43,,,,,,,,,2.00E-41,CHOYP_BRAFLDRAFT_125670.1.1,,,,,,,,, comp141561_c0_seq1,4522,45.0907,0.38739671,2481,8059,,0,Q13435,Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (SF3b150) (Spliceosome-associated protein 145) (SAP 145),Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (SF3b150) (Spliceosome-associated protein 145) (SAP 145),GO:0005689; GO:0071013; GO:0000398; GO:0019048; GO:0003676; GO:0005654,"U12-type spliceosomal complex; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; modulation by virus of host morphology or physiology; nucleic acid binding; nucleoplasm",PF04037;PF04046;PF02037;,0,CHOYP_LOC101063699.1.1,5.00E-70,ruditapes_c9898,,,,,SF3B2_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; viral process [GO:0016032]" comp141564_c0_seq1,2032,38.8287,0.6556797,26,167,,3.00E-148,Q55DV9,Cystathionine gamma-lyase (EC 4.4.1.1) (Gamma-cystathionase),Cystathionine gamma-lyase (EC 4.4.1.1) (Gamma-cystathionase),GO:0080146; GO:0044540; GO:0004123; GO:0019344; GO:0006534; GO:0005737; GO:0030170,L-cysteine desulfhydrase activity; L-cystine L-cysteine-lyase (deaminating); cystathionine gamma-lyase activity; cysteine biosynthetic process; cysteine metabolic process; cytoplasm; pyridoxal phosphate binding,PF01053;,,,,,,,,,CGL_DICDI,Dictyostelium discoideum (Slime mold),'de novo' L-methionine biosynthetic process [GO:0071266]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; transsulfuration [GO:0019346] comp141564_c0_seq2,2019,38.9302,0.68264105,31,282,,7.00E-168,Q58DW2,Cystathionine gamma-lyase (EC 4.4.1.1) (Cysteine-protein sulfhydrase) (Gamma-cystathionase),Cystathionine gamma-lyase (EC 4.4.1.1) (Cysteine-protein sulfhydrase) (Gamma-cystathionase),GO:0080146; GO:0044540; GO:0004123; GO:0019344; GO:0005737; GO:0070814; GO:0043066; GO:0043123; GO:0051092; GO:0044524; GO:0018272; GO:0030170,L-cysteine desulfhydrase activity; L-cystine L-cysteine-lyase (deaminating); cystathionine gamma-lyase activity; cysteine biosynthetic process; cytoplasm; hydrogen sulfide biosynthetic process; negative regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; protein sulfhydration; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; pyridoxal phosphate binding,PF01053;,1.00E-158,CHOYP_CGL.1.2,,,,,,,CGL_BOVIN,Bos taurus (Bovine),'de novo' L-methionine biosynthetic process [GO:0071266]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; hydrogen sulfide biosynthetic process [GO:0070814]; negative regulation of apoptotic process [GO:0043066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; protein sulfhydration [GO:0044524]; transsulfuration [GO:0019346] comp141564_c0_seq4,2816,30.5043,0.44302547,125,814,,6.00E-23,O75506,Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13),Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13),GO:0005856; GO:0006936; GO:0000122; GO:0005634; GO:0003714,cytoskeleton; muscle contraction; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription corepressor activity,PF06825;,1.00E-40,CHOYP_LOC100123755.4.5,1.00E-55,ruditapes_c8225,,,,,HSBP1_HUMAN,Homo sapiens (Human),endodermal cell differentiation [GO:0035987]; muscle contraction [GO:0006936]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cellular response to heat [GO:1900034] comp141567_c0_seq2,3054,35.036,0.36375547,42,89,,4.00E-11,Q6MG82,Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),GO:0030054; GO:0016021; GO:0005886; GO:0009607; GO:0045202,cell junction; integral to membrane; plasma membrane; response to biotic stimulus; synapse,PF04505;,,,,,,,,,PRRT1_RAT,Rattus norvegicus (Rat),response to biotic stimulus [GO:0009607] comp141567_c0_seq5,3017,34.7033,0.36408506,13,3,,4.00E-11,Q6MG82,Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1),GO:0030054; GO:0016021; GO:0005886; GO:0009607; GO:0045202,cell junction; integral to membrane; plasma membrane; response to biotic stimulus; synapse,PF04505;,,,,,,,,,PRRT1_RAT,Rattus norvegicus (Rat),response to biotic stimulus [GO:0009607] comp141569_c0_seq1,890,43.3708,0.55136208,595,1640,,5.00E-10,Q9PII5,Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20),Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20),GO:0008836; GO:0009089; GO:0030170,diaminopimelate decarboxylase activity; lysine biosynthetic process via diaminopimelate; pyridoxal phosphate binding,PF02784;PF00278;,,,,,,,,,DCDA_CAMJE,Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168),lysine biosynthetic process via diaminopimelate [GO:0009089] comp141569_c1_seq1,2821,33.4988,0.48037061,3402,9456,,2.00E-79,P00860,Ornithine decarboxylase (ODC) (EC 4.1.1.17),Ornithine decarboxylase (ODC) (EC 4.1.1.17),GO:0005829; GO:0001822; GO:0004586; GO:0008284; GO:0033387; GO:0009615,cytosol; kidney development; ornithine decarboxylase activity; positive regulation of cell proliferation; putrescine biosynthetic process from ornithine; response to virus,PF02784;PF00278;,9.00E-73,CHOYP_LOC100374422.1.2,1.00E-12,ruditapes2_c1687,,,,,DCOR_MOUSE,Mus musculus (Mouse),kidney development [GO:0001822]; positive regulation of cell proliferation [GO:0008284]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615] comp141571_c0_seq1,3148,32.7192,0.4744944,546,1959,,2.00E-33,Q5I0B5,Eukaryotic translation initiation factor 3 subunit J (eIF3j) (Eukaryotic translation initiation factor 3 subunit 1) (eIF-3-alpha) (eIF3 p35),Eukaryotic translation initiation factor 3 subunit J (eIF3j) (Eukaryotic translation initiation factor 3 subunit 1) (eIF-3-alpha) (eIF3 p35),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity,PF08597;,,,2.00E-41,ruditapes_c1366,,,,,EIF3J_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cytoplasmic translation [GO:0002181]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] comp141572_c0_seq2,986,42.4949,0.93095738,0,0,,3.00E-10,Q5XH36,Cysteine-rich with EGF-like domain protein 2-A,Cysteine-rich with EGF-like domain protein 2-A,GO:0005509; GO:0005783; GO:0005576,calcium ion binding; endoplasmic reticulum; extracellular region,PF11938;PF07645;,,,,,,,,,CRE2A_XENLA,Xenopus laevis (African clawed frog), comp141572_c0_seq3,1630,44.1104,0.65363061,0,0,,5.00E-58,P37889,Fibulin-2 (FIBL-2),Fibulin-2 (FIBL-2),GO:0005509; GO:0050840; GO:0010811; GO:0005578,calcium ion binding; extracellular matrix binding; positive regulation of cell-substrate adhesion; proteinaceous extracellular matrix,PF01821;PF12662;PF07645;,4.00E-37,CHOYP_FBLN2.1.1,,,,,,,FBLN2_MOUSE,Mus musculus (Mouse),positive regulation of cell-substrate adhesion [GO:0010811] comp141572_c0_seq4,1531,44.8073,0.67737685,0,0,,2.00E-70,O77469,Fibulin-1,Fibulin-1,GO:0005604; GO:0005509; GO:0030198; GO:0005201; GO:0007275; GO:0040017; GO:0005578,basement membrane; calcium ion binding; extracellular matrix organization; extracellular matrix structural constituent; multicellular organismal development; positive regulation of locomotion; proteinaceous extracellular matrix,PF12662;PF07645;,,,,,,,,,FBLN1_CAEEL,Caenorhabditis elegans,extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; positive regulation of locomotion [GO:0040017] comp141572_c0_seq5,961,45.5775,0.92767699,0,0,,2.00E-25,O08746,Matrilin-2,Matrilin-2,GO:0007411; GO:0005604; GO:0005509; GO:0031104; GO:0008347; GO:0001764; GO:0048678,axon guidance; basement membrane; calcium ion binding; dendrite regeneration; glial cell migration; neuron migration; response to axon injury,PF07645;PF10393;PF00092;,,,,,,,,,MATN2_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; response to axon injury [GO:0048678] comp141572_c0_seq6,1641,43.9976,0.64038088,0,23,,1.00E-65,Q8MJJ9,Fibulin-1 (FIBL-1) (Fragment),Fibulin-1 (FIBL-1) (Fragment),GO:0005509; GO:0005578,calcium ion binding; proteinaceous extracellular matrix,PF12662;PF07645;,,,,,,,,,FBLN1_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),extracellular matrix organization [GO:0030198] comp141572_c0_seq7,1542,44.6822,0.6632112,0,0,,1.00E-75,O77469,Fibulin-1,Fibulin-1,GO:0005604; GO:0005509; GO:0030198; GO:0005201; GO:0007275; GO:0040017; GO:0005578,basement membrane; calcium ion binding; extracellular matrix organization; extracellular matrix structural constituent; multicellular organismal development; positive regulation of locomotion; proteinaceous extracellular matrix,PF12662;PF07645;,,,,,,,,,FBLN1_CAEEL,Caenorhabditis elegans,extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; positive regulation of locomotion [GO:0040017] comp141572_c0_seq8,387,41.6021,1.2010507,0,0,,6.00E-07,Q9LMN7,Wall-associated receptor kinase 5 (EC 2.7.11.-),Wall-associated receptor kinase 5 (EC 2.7.11.-),GO:0005524; GO:0005509; GO:0016021; GO:0030247; GO:0004674,ATP binding; calcium ion binding; integral to membrane; polysaccharide binding; protein serine/threonine kinase activity,PF07645;PF13947;PF07714;,,,,,,,,,WAK5_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell surface receptor signaling pathway [GO:0007166] comp141573_c0_seq2,2686,40.0223,0.25501965,231,1191,,2.00E-08,P57678,Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97),Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97),GO:0097504; GO:0005829; GO:0005730; GO:0005654; GO:0006364; GO:0030532; GO:0005681; GO:0000387,Gemini of coiled bodies; cytosol; nucleolus; nucleoplasm; rRNA processing; small nuclear ribonucleoprotein complex; spliceosomal complex; spliceosomal snRNP assembly,,,,,,,,,,GEMI4_HUMAN,Homo sapiens (Human),nuclear import [GO:0051170]; rRNA processing [GO:0006364]; spliceosomal snRNP assembly [GO:0000387] comp141574_c0_seq1,1529,37.6063,0.31613121,87,884,,2.00E-06,Q5SU73,Coilin (p80),Coilin (p80-coilin),GO:0015030; GO:0015036; GO:0001674,Cajal body; disulfide oxidoreductase activity; female germ cell nucleus,PF15862;,,,,,,,,,COIL_MOUSE,Mus musculus (Mouse), comp141575_c2_seq1,2293,36.8077,0.79953694,17,119,,7.00E-114,Q5ZJU3,Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase),Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase),GO:0005524; GO:0070981; GO:0004066; GO:0006541,ATP binding; L-asparagine biosynthetic process; asparagine synthase (glutamine-hydrolyzing) activity; glutamine metabolic process,PF00733;PF13537;,2.00E-55,CHOYP_LOC100369657.2.2,,,,,,,ASNS_CHICK,Gallus gallus (Chicken),asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981] comp141575_c2_seq2,3121,40.1794,0.88239482,11,209,,0,Q5ZJU3,Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase),Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase),GO:0005524; GO:0070981; GO:0004066; GO:0006541,ATP binding; L-asparagine biosynthetic process; asparagine synthase (glutamine-hydrolyzing) activity; glutamine metabolic process,PF00733;PF13537;,4.00E-65,CHOYP_LOC100369657.2.2,,,,,,,ASNS_CHICK,Gallus gallus (Chicken),asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981] comp141577_c0_seq1,3553,37.8835,0.41861016,1925,5866,,0,Q9Y4W6,AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein),AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein),GO:0005524; GO:0007409; GO:0008219; GO:0042407; GO:0016021; GO:0004222; GO:0008053; GO:0005743; GO:0034982; GO:0005739; GO:0048747; GO:0042552; GO:0021675; GO:0007528; GO:0017111; GO:0006508; GO:0040014; GO:0060013; GO:0051082; GO:0008270,ATP binding; axonogenesis; cell death; cristae formation; integral to membrane; metalloendopeptidase activity; mitochondrial fusion; mitochondrial inner membrane; mitochondrial protein processing; mitochondrion; muscle fiber development; myelination; nerve development; neuromuscular junction development; nucleoside-triphosphatase activity; proteolysis; regulation of multicellular organism growth; righting reflex; unfolded protein binding; zinc ion binding,PF00004;PF06480;PF01434;,1.00E-155,CHOYP_AFG32.1.1,,,,,,,AFG32_HUMAN,Homo sapiens (Human),axonogenesis [GO:0007409]; cristae formation [GO:0042407]; mitochondrial fusion [GO:0008053]; mitochondrial protein processing [GO:0034982]; muscle fiber development [GO:0048747]; myelination [GO:0042552]; nerve development [GO:0021675]; neuromuscular junction development [GO:0007528]; protein complex assembly [GO:0006461]; protein import into mitochondrial intermembrane space [GO:0045041]; regulation of multicellular organism growth [GO:0040014]; righting reflex [GO:0060013] comp141578_c0_seq1,1444,44.3906,0.33355094,31,3,,1.00E-25,Q07139,Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene),Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene),GO:0005096; GO:0005089; GO:0032863; GO:0032147; GO:0000902; GO:0071277; GO:0070301; GO:0071479; GO:0097149; GO:0032154; GO:0000910; GO:0005737; GO:0035556; GO:0030496; GO:0005634; GO:0043089; GO:0043123; GO:0043065; GO:0032467; GO:0045666; GO:0042307; GO:0042803; GO:0051260; GO:0015031; GO:0051988; GO:0004871; GO:0005923; GO:0070830,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; activation of Rac GTPase activity; activation of protein kinase activity; cell morphogenesis; cellular response to calcium ion; cellular response to hydrogen peroxide; cellular response to ionizing radiation; centralspindlin complex; cleavage furrow; cytokinesis; cytoplasm; intracellular signal transduction; midbody; nucleus; positive regulation of Cdc42 GTPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of cytokinesis; positive regulation of neuron differentiation; positive regulation of protein import into nucleus; protein homodimerization activity; protein homooligomerization; protein transport; regulation of attachment of spindle microtubules to kinetochore; signal transducer activity; tight junction; tight junction assembly,PF00533;PF12738;PF00621;,,,,,,,,,ECT2_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of protein kinase activity [GO:0045859]; regulation of Rho protein signal transduction [GO:0035023] comp141578_c0_seq2,1845,44.7154,0.33311288,7,0,,4.00E-103,Q800K6,DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP),DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP),GO:0003677; GO:0006281; GO:0000076; GO:0006270; GO:0071165; GO:0000785; GO:0003682; GO:0005737; GO:0005815; GO:0005634; GO:0035563; GO:0033138; GO:0045860; GO:0071168; GO:0030174; GO:0006974; GO:0000922,DNA binding; DNA repair; DNA replication checkpoint; DNA replication initiation; GINS complex assembly; chromatin; chromatin binding; cytoplasm; microtubule organizing center; nucleus; positive regulation of chromatin binding; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase activity; protein localization to chromatin; regulation of DNA-dependent DNA replication initiation; response to DNA damage stimulus; spindle pole,PF00533;PF12738;,,,,,,,,,TOB1A_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp141578_c0_seq7,771,44.0986,0.21768744,5,0,,,,,,,,,1.00E-19,CHOYP_TOPB1.1.1,,,,,,,,, comp141582_c0_seq2,2708,35.6721,0.49321168,3,20,,7.00E-19,O08848,60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2),60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2),GO:0003723; GO:0060271; GO:0005737; GO:0046872; GO:0030529,RNA binding; cilium morphogenesis; cytoplasm; metal ion binding; ribonucleoprotein complex,PF05731;,,,,,,,,,RO60_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224] comp141584_c1_seq1,1922,43.1322,0.3477397,219,1538,,0,Q5R698,Protein arginine N-methyltransferase 5 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT5) (EC 2.1.1.125) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog),Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (Histone-arginine N-methyltransferase PRMT5) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog),GO:0005737; GO:0042118; GO:0034969; GO:0008469; GO:0005634; GO:0035243; GO:0006355; GO:0000387; GO:0006351,"cytoplasm; endothelial cell activation; histone arginine methylation; histone-arginine N-methyltransferase activity; nucleus; protein-arginine omega-N symmetric methyltransferase activity; regulation of transcription, DNA-dependent; spliceosomal snRNP assembly; transcription, DNA-dependent",PF05185;,0,CHOYP_ANM5.1.1,,,,,,,ANM5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"circadian regulation of gene expression [GO:0032922]; DNA-templated transcription, termination [GO:0006353]; endothelial cell activation [GO:0042118]; Golgi ribbon formation [GO:0090161]; histone H4-R3 methylation [GO:0043985]; peptidyl-arginine methylation [GO:0018216]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]" comp141584_c1_seq2,1180,42.7966,0.38995311,1,27,,1.00E-11,B0W3L6,Histone-arginine methyltransferase CARMER (EC 2.1.1.-) (EC 2.1.1.125),Histone-arginine methyltransferase CARMER (EC 2.1.1.319),GO:0006338; GO:0005737; GO:0034969; GO:0042054; GO:0008469; GO:0005634; GO:0035242; GO:0035241; GO:0006355; GO:0006351,"chromatin remodeling; cytoplasm; histone arginine methylation; histone methyltransferase activity; histone-arginine N-methyltransferase activity; nucleus; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05185;,,,,,,,,,CARM1_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),"chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141592_c0_seq2,685,29.0511,0.27801478,24,111,,8.00E-19,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,3.00E-21,CHOYP_LOC100537145.2.3,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp141594_c0_seq1,1026,32.4561,0.44455709,368,284,,9.00E-17,Q6DC17,Mitotic-spindle organizing protein 2 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2),Mitotic-spindle organizing protein 2 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2),GO:0005813; GO:0008274; GO:0005819,centrosome; gamma-tubulin ring complex; spindle,PF12926;,,,,,,,,,MZT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141595_c0_seq1,2447,38.1692,0.60181188,0,0,,7.00E-17,Q8CGF7,Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),GO:0001106; GO:0005634; GO:0070064; GO:0003700; GO:0006351,"RNA polymerase II transcription corepressor activity; nucleus; proline-rich region binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01846;PF00397;,,,,,,,,,TCRG1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp141595_c0_seq2,4170,40.6235,0.56783426,4,138,,1.00E-123,Q9WV92,"Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]","Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]",GO:0006915; GO:0005911; GO:0030866; GO:0030865; GO:0005737; GO:0007016; GO:0005856; GO:0019898; GO:0044224; GO:0043217; GO:0048812; GO:0030913; GO:0033270; GO:0005886; GO:0071205; GO:0002175; GO:0072659; GO:0008360; GO:0005200,apoptotic process; cell-cell junction; cortical actin cytoskeleton organization; cortical cytoskeleton organization; cytoplasm; cytoskeletal anchoring at plasma membrane; cytoskeleton; extrinsic to membrane; juxtaparanode region of axon; myelin maintenance; neuron projection morphogenesis; paranodal junction assembly; paranode region of axon; plasma membrane; protein localization to juxtaparanode region of axon; protein localization to paranode region of axon; protein localization to plasma membrane; regulation of cell shape; structural constituent of cytoskeleton,PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;,2.00E-71,CHOYP_LOC100373842.4.4,,,,,,,E41L3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360] comp141595_c0_seq3,4227,40.6908,0.56396355,0,0,,2.00E-117,O43491,Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G),Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G),GO:0030054; GO:0030866; GO:0019898; GO:0005634; GO:0005886; GO:0008091; GO:0005198,cell junction; cortical actin cytoskeleton organization; extrinsic to membrane; nucleus; plasma membrane; spectrin; structural molecule activity,PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;,2.00E-38,CHOYP_E41L3.2.2,7.00E-87,ruditapes_c8957,,,,,E41L2_HUMAN,Homo sapiens (Human),cortical actin cytoskeleton organization [GO:0030866] comp141595_c0_seq4,3966,40.2168,0.54139468,0,0,,2.00E-69,P29074,Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),GO:0005737; GO:0005856; GO:0009898; GO:0004726,cytoplasm; cytoskeleton; internal side of plasma membrane; non-membrane spanning protein tyrosine phosphatase activity,PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;,2.00E-71,CHOYP_LOC100373842.4.4,,,,,,,PTN4_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470] comp141595_c0_seq6,4023,40.343,0.54255075,0,0,,9.00E-118,O43491,Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G),Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G),GO:0030054; GO:0030866; GO:0019898; GO:0005634; GO:0005886; GO:0008091; GO:0005198,cell junction; cortical actin cytoskeleton organization; extrinsic to membrane; nucleus; plasma membrane; spectrin; structural molecule activity,PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;,2.00E-38,CHOYP_E41L3.2.2,,,,,,,E41L2_HUMAN,Homo sapiens (Human),cortical actin cytoskeleton organization [GO:0030866] comp141595_c0_seq7,4371,40.7687,0.56640759,0,0,,2.00E-123,Q9WV92,"Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]","Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]",GO:0006915; GO:0005911; GO:0030866; GO:0030865; GO:0005737; GO:0007016; GO:0005856; GO:0019898; GO:0044224; GO:0043217; GO:0048812; GO:0030913; GO:0033270; GO:0005886; GO:0071205; GO:0002175; GO:0072659; GO:0008360; GO:0005200,apoptotic process; cell-cell junction; cortical actin cytoskeleton organization; cortical cytoskeleton organization; cytoplasm; cytoskeletal anchoring at plasma membrane; cytoskeleton; extrinsic to membrane; juxtaparanode region of axon; myelin maintenance; neuron projection morphogenesis; paranodal junction assembly; paranode region of axon; plasma membrane; protein localization to juxtaparanode region of axon; protein localization to paranode region of axon; protein localization to plasma membrane; regulation of cell shape; structural constituent of cytoskeleton,PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;,2.00E-71,CHOYP_E41L3.1.2,,,,,,,E41L3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360] comp141595_c0_seq8,2651,38.891,0.63322831,0,0,,3.00E-17,Q8CGF7,Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),GO:0001106; GO:0005634; GO:0070064; GO:0003700; GO:0006351,"RNA polymerase II transcription corepressor activity; nucleus; proline-rich region binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01846;PF00397;,,,,,,,,,TCRG1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp141595_c0_seq9,4167,40.4368,0.54625388,15,58,,8.00E-124,Q9WV92,"Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]","Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]",GO:0006915; GO:0005911; GO:0030866; GO:0030865; GO:0005737; GO:0007016; GO:0005856; GO:0019898; GO:0044224; GO:0043217; GO:0048812; GO:0030913; GO:0033270; GO:0005886; GO:0071205; GO:0002175; GO:0072659; GO:0008360; GO:0005200,apoptotic process; cell-cell junction; cortical actin cytoskeleton organization; cortical cytoskeleton organization; cytoplasm; cytoskeletal anchoring at plasma membrane; cytoskeleton; extrinsic to membrane; juxtaparanode region of axon; myelin maintenance; neuron projection morphogenesis; paranodal junction assembly; paranode region of axon; plasma membrane; protein localization to juxtaparanode region of axon; protein localization to paranode region of axon; protein localization to plasma membrane; regulation of cell shape; structural constituent of cytoskeleton,PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;,2.00E-71,CHOYP_LOC100373842.4.4,,,,,,,E41L3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360] comp141596_c0_seq6,2590,37.4131,0.45352517,1671,7993,,4.00E-124,P67874,Casein kinase II subunit beta (CK II beta) (Phosvitin),Casein kinase II subunit beta (CK II beta) (Phosvitin),GO:0007249; GO:0016055; GO:0046872; GO:0030177; GO:0005956; GO:0019887; GO:0045859,I-kappaB kinase/NF-kappaB cascade; Wnt receptor signaling pathway; metal ion binding; positive regulation of Wnt receptor signaling pathway; protein kinase CK2 complex; protein kinase regulator activity; regulation of protein kinase activity,PF01214;,6.00E-157,CHOYP_CSK2B.1.1,,,1.00E-155,AM858460.p.cg.6,9,,CSK2B_RAT,Rattus norvegicus (Rat),adiponectin-activated signaling pathway [GO:0033211]; endothelial tube morphogenesis [GO:0061154]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055] comp141598_c0_seq1,1376,47.0203,0.63322509,0,0,,4.00E-117,P47942,Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (Turned on after division 64 kDa protein) (TOAD-64),Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (Turned on after division 64 kDa protein) (TOAD-64),GO:0030424; GO:0007010; GO:0005829; GO:0030425; GO:0006897; GO:0030426; GO:0016812; GO:0005739; GO:0043025; GO:0021772; GO:0014049; GO:0043234; GO:0006208; GO:0030516; GO:0001975; GO:0042220; GO:0042493; GO:0021510; GO:0048489,"axon; cytoskeleton organization; cytosol; dendrite; endocytosis; growth cone; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; mitochondrion; neuronal cell body; olfactory bulb development; positive regulation of glutamate secretion; protein complex; pyrimidine nucleobase catabolic process; regulation of axon extension; response to amphetamine; response to cocaine; response to drug; spinal cord development; synaptic vesicle transport",PF01979;,,,,,,,,,DPYL2_RAT,Rattus norvegicus (Rat),axon guidance [GO:0007411]; brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; olfactory bulb development [GO:0021772]; positive regulation of glutamate secretion [GO:0014049]; regulation of axon extension [GO:0030516]; regulation of neuron differentiation [GO:0045664]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; spinal cord development [GO:0021510]; synaptic vesicle transport [GO:0048489] comp141598_c0_seq13,1376,46.9477,0.63550824,0,0,,4.00E-86,Q9BPU6,Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6),Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6),GO:0007411; GO:0005829; GO:0030425; GO:0016812; GO:0043025; GO:0043234; GO:0006208; GO:0007165,"axon guidance; cytosol; dendrite; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; neuronal cell body; protein complex; pyrimidine nucleobase catabolic process; signal transduction",PF01979;,,,,,,,,,DPYL5_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; nervous system development [GO:0007399]; signal transduction [GO:0007165] comp141598_c0_seq14,440,45.2273,0.52739998,0,0,,,,,,,,,6.00E-72,CHOYP_LOC100372131.2.2,,,,,,,,, comp141598_c0_seq15,1056,46.4015,0.65684209,0,0,,6.00E-130,Q14117,Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase),Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase),GO:0016597; GO:0019482; GO:0005829; GO:0004157; GO:0051289; GO:0046135; GO:0002059; GO:0006210; GO:0002058; GO:0006212; GO:0008270,amino acid binding; beta-alanine metabolic process; cytosol; dihydropyrimidinase activity; protein homotetramerization; pyrimidine nucleoside catabolic process; thymine binding; thymine catabolic process; uracil binding; uracil catabolic process; zinc ion binding,PF01979;,1.00E-142,CHOYP_LOC100372131.1.2,,,,,,,DPYS_HUMAN,Homo sapiens (Human),beta-alanine metabolic process [GO:0019482]; protein homotetramerization [GO:0051289]; pyrimidine nucleobase catabolic process [GO:0006208]; pyrimidine nucleoside catabolic process [GO:0046135]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212] comp141598_c0_seq2,1092,46.1538,0.65953211,0,0,,1.00E-10,Q8TSA6,Dihydroorotase (DHOase) (EC 3.5.2.3),Dihydroorotase (DHOase) (EC 3.5.2.3),GO:0044205; GO:0004151; GO:0008270,'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding,PF01979;,,,,,,,,,PYRC_METAC,Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A),'de novo' UMP biosynthetic process [GO:0044205] comp141598_c0_seq4,1092,46.2454,0.65620809,0,0,,1.00E-71,Q9I676,D-hydantoinase/dihydropyrimidinase (DHPase) (EC 3.5.2.2),D-hydantoinase/dihydropyrimidinase (DHPase) (EC 3.5.2.2),GO:0005737; GO:0004157; GO:0046872; GO:0009117; GO:0006208,cytoplasm; dihydropyrimidinase activity; metal ion binding; nucleotide metabolic process; pyrimidine nucleobase catabolic process,PF01979;,,,,,,,,,HYDA_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), comp141598_c0_seq5,762,42.2572,0.85376541,47,164,,8.00E-14,B3E3I1,Dihydroorotase (DHOase) (EC 3.5.2.3),Dihydroorotase (DHOase) (EC 3.5.2.3),GO:0044205; GO:0004151; GO:0008270,'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding,PF01979;,,,,,,,,,PYRC_GEOLS,Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ),'de novo' UMP biosynthetic process [GO:0044205] comp141598_c0_seq6,1340,47.1642,0.63301129,0,0,,7.00E-128,Q14117,Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase),Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase),GO:0016597; GO:0019482; GO:0005829; GO:0004157; GO:0051289; GO:0046135; GO:0002059; GO:0006210; GO:0002058; GO:0006212; GO:0008270,amino acid binding; beta-alanine metabolic process; cytosol; dihydropyrimidinase activity; protein homotetramerization; pyrimidine nucleoside catabolic process; thymine binding; thymine catabolic process; uracil binding; uracil catabolic process; zinc ion binding,PF01979;,,,,,,,,,DPYS_HUMAN,Homo sapiens (Human),beta-alanine metabolic process [GO:0019482]; protein homotetramerization [GO:0051289]; pyrimidine nucleobase catabolic process [GO:0006208]; pyrimidine nucleoside catabolic process [GO:0046135]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212] comp141598_c0_seq7,966,49.1718,0.62053542,0,0,,2.00E-110,Q14194,Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Unc-33-like phosphoprotein 3) (ULIP-3),Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Unc-33-like phosphoprotein 3) (ULIP-3),GO:0007411; GO:0005829; GO:0030425; GO:0016812; GO:0043231; GO:0005815; GO:0043025; GO:0006139; GO:0006208; GO:0005819,"axon guidance; cytosol; dendrite; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; intracellular membrane-bounded organelle; microtubule organizing center; neuronal cell body; nucleobase-containing compound metabolic process; pyrimidine nucleobase catabolic process; spindle",PF01979;,1.00E-142,CHOYP_LOC100372131.1.2,,,,,,,DPYL1_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of actin filament binding [GO:1904530]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; nucleobase-containing compound metabolic process [GO:0006139] comp141598_c0_seq8,1340,47.0896,0.63536599,0,0,,2.00E-10,Q8TSA6,Dihydroorotase (DHOase) (EC 3.5.2.3),Dihydroorotase (DHOase) (EC 3.5.2.3),GO:0044205; GO:0004151; GO:0008270,'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding,PF01979;,,,,,,,,,PYRC_METAC,Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A),'de novo' UMP biosynthetic process [GO:0044205] comp141598_c0_seq9,463,46.4363,0.63250022,0,0,,,,,,,,,3.00E-70,CHOYP_LOC100372131.2.2,,,,,,,,, comp141599_c0_seq3,1364,41.7889,0.4418303,45,123,,2.00E-58,Q9UBY0,Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2),Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2),GO:0016021; GO:0005886; GO:0008104; GO:0006885; GO:0015385,integral to membrane; plasma membrane; protein localization; regulation of pH; sodium:hydrogen antiporter activity,PF00999;PF16644;,3.00E-11,CHOYP_AAEL_AAEL001503.1.1,,,,,,,SL9A2_HUMAN,Homo sapiens (Human),ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; protein localization [GO:0008104]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] comp141599_c0_seq4,1445,44.083,0.92442358,54,102,,7.00E-27,P48762,Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1),Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1),GO:0048306; GO:0071468; GO:0005783; GO:0005789; GO:0016021; GO:0005886; GO:0051259; GO:0051453; GO:0001101; GO:0071436; GO:0015385,calcium-dependent protein binding; cellular response to acidity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; plasma membrane; protein oligomerization; regulation of intracellular pH; response to acid; sodium ion export; sodium:hydrogen antiporter activity,PF00999;PF16644;,2.00E-33,CHOYP_LOC100898717.1.3,,,,,,,SL9A1_PIG,Sus scrofa (Pig),cellular response to acidic pH [GO:0071468]; protein oligomerization [GO:0051259]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; response to acidic pH [GO:0010447]; sodium ion export [GO:0071436] comp141603_c0_seq1,4507,44.3089,0.32709135,404,219,,0,Q8QGX4,DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),GO:0005524; GO:0003677; GO:0004677; GO:0000724; GO:0006303; GO:0070419; GO:0005730; GO:0005654,ATP binding; DNA binding; DNA-dependent protein kinase activity; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end joining; nonhomologous end joining complex; nucleolus; nucleoplasm,PF02259;PF02260;PF08163;PF00454;,2.00E-121,CHOYP_BRAFLDRAFT_85202.2.2,,,,,,,PRKDC_CHICK,Gallus gallus (Chicken),DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431] comp141604_c1_seq2,1644,39.6594,0.52938468,0,0,,2.00E-153,B1H120,Septin-8,Septin-8,GO:0005525; GO:0007049; GO:0031105,GTP binding; cell cycle; septin complex,PF00735;,0,CHOYP_SEP11.1.2,,,,,,,SEPT8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141604_c1_seq3,2100,36.619,0.47372208,46,69,,2.00E-63,Q08DM7,Neuronal-specific septin-3,Neuronal-specific septin-3,GO:0005525; GO:0007049; GO:0051301; GO:0030054; GO:0031105; GO:0045202,GTP binding; cell cycle; cell division; cell junction; septin complex; synapse,PF00735;,0,CHOYP_SEP11.2.2,,,,,,,SEPT3_BOVIN,Bos taurus (Bovine),cell cycle [GO:0007049]; cell division [GO:0051301] comp141606_c0_seq11,2480,44.5565,0.64155041,0,0,,6.00E-26,A6NI56,Coiled-coil domain-containing protein 154,Coiled-coil domain-containing protein 154,GO:0005769,early endosome,PF15450;,,,,,,,,,CC154_HUMAN,Homo sapiens (Human), comp141606_c0_seq12,1572,43.7023,0.67422741,0,0,,,,,,,,,5.00E-41,CHOYP_LOC580909.1.2,,,,,,,,, comp141606_c0_seq15,1239,43.5028,0.73098538,0,0,,4.00E-19,A6NI56,Coiled-coil domain-containing protein 154,Coiled-coil domain-containing protein 154,GO:0005769,early endosome,PF15450;,,,,,,,,,CC154_HUMAN,Homo sapiens (Human), comp141606_c0_seq4,1799,44.6359,0.57357008,0,0,,,,,,,,,6.00E-41,CHOYP_LOC580909.1.2,,,,,,,,, comp141606_c0_seq5,2226,43.8904,0.70892653,0,0,,2.00E-24,A6NI56,Coiled-coil domain-containing protein 154,Coiled-coil domain-containing protein 154,GO:0005769,early endosome,PF15450;,4.00E-38,CHOYP_LOC100370844.1.2,,,,,,,CC154_HUMAN,Homo sapiens (Human), comp141606_c0_seq8,1545,43.6893,0.65722816,0,0,,,,,,,,,5.00E-41,CHOYP_LOC580909.1.2,,,,,,,,, comp141608_c0_seq1,1872,40.3312,0.97489511,42,57,,1.00E-69,Q9R0Y5,Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase),Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase),GO:0005524; GO:0046034; GO:0004017; GO:0007050; GO:0005737; GO:0004550; GO:0009142; GO:0001520; GO:0005886; GO:0036126,ATP binding; ATP metabolic process; adenylate kinase activity; cell cycle arrest; cytoplasm; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; outer dense fiber; plasma membrane; sperm flagellum,,,,,,,,,,KAD1_MOUSE,Mus musculus (Mouse),ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cell cycle arrest [GO:0007050]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp141608_c0_seq2,1886,40.0848,0.95054231,18,48,,2.00E-44,P15700,Uridylate kinase (UK) (EC 2.7.4.14) (ATP:UMP phosphotransferase) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Suppressor of cdc8 protein) (Uridine monophosphate kinase) (UMP kinase) (UMPK),Uridylate kinase (UK) (EC 2.7.4.14) (ATP:UMP phosphotransferase) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Suppressor of cdc8 protein) (Uridine monophosphate kinase) (UMP kinase) (UMPK),GO:0006207; GO:0005524; GO:0004017; GO:0004127; GO:0005737; GO:0005634; GO:0006221; GO:0009041,'de novo' pyrimidine nucleobase biosynthetic process; ATP binding; adenylate kinase activity; cytidylate kinase activity; cytoplasm; nucleus; pyrimidine nucleotide biosynthetic process; uridylate kinase activity,,4.00E-56,CHOYP_VOLCADRAFT_121426.1.1,1.00E-72,ruditapes_c13762,,,,,UMPK_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleotide biosynthetic process [GO:0006221] comp141608_c0_seq3,818,46.577,0.98000146,72,185,,6.00E-74,P39069,Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase),Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase),GO:0006172; GO:0046033; GO:0005524; GO:0046034; GO:0046083; GO:0004017; GO:0021549; GO:0046103; GO:0007517; GO:0030182; GO:0043005; GO:0004550; GO:0009142; GO:0021772; GO:0048471; GO:0010828; GO:0014042; GO:0014823; GO:0042493; GO:0032355; GO:0033574; GO:0030017,ADP biosynthetic process; AMP metabolic process; ATP binding; ATP metabolic process; adenine metabolic process; adenylate kinase activity; cerebellum development; inosine biosynthetic process; muscle organ development; neuron differentiation; neuron projection; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; olfactory bulb development; perinuclear region of cytoplasm; positive regulation of glucose transport; positive regulation of neuron maturation; response to activity; response to drug; response to estradiol stimulus; response to testosterone stimulus; sarcomere,,1.00E-52,CHOYP_VOLCADRAFT_121426.1.1,,,,,,,KAD1_RAT,Rattus norvegicus (Rat),adenine metabolic process [GO:0046083]; ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cerebellum development [GO:0021549]; inosine biosynthetic process [GO:0046103]; muscle organ development [GO:0007517]; neuron differentiation [GO:0030182]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; olfactory bulb development [GO:0021772]; positive regulation of glucose transport [GO:0010828]; positive regulation of neuron maturation [GO:0014042]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to testosterone [GO:0033574] comp141610_c0_seq1,1191,37.1117,0.41489761,11,97,,,,,,,,,1.00E-22,CHOYP_NEMVEDRAFT_V1G238047.1.1,4.00E-20,ruditapes_lrc36380,,,,,,, comp141610_c0_seq2,1126,37.6554,0.40129107,10,68,,,,,,,,,3.00E-23,CHOYP_LOC660225.1.1,3.00E-15,ruditapes_lrc33282,,,,,,, comp141615_c0_seq2,1556,39.7815,0.65225614,193,1074,,9.00E-30,Q17NH9,Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11),Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF10280;,2.00E-14,CHOYP_LOC100369524.1.1,1.00E-84,ruditapes_c11690,,,,,MED11_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"transcription, DNA-templated [GO:0006351]" comp141617_c0_seq1,552,44.7464,0.55255977,19,41,,2.00E-45,Q9W0E8,Protein zer-1 homolog (Zyg-11 homolog B-like protein),Protein zer-1 homolog (Zyg-11 homolog B-like protein),GO:0031462; GO:0051438; GO:0004842,Cul2-RING ubiquitin ligase complex; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,,,,,,,,,,ZER1_DROME,Drosophila melanogaster (Fruit fly),regulation of ubiquitin-protein transferase activity [GO:0051438] comp141617_c2_seq3,2331,36.1218,0.45897017,0,7,,1.00E-65,Q2WF59,Zyg eleven-related protein 1 (zyg-11-related protein),Zyg eleven-related protein 1 (zyg-11-related protein),GO:0031462; GO:0051438; GO:0004842,Cul2-RING ubiquitin ligase complex; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,,,,,,,,,,ZER1_CAEEL,Caenorhabditis elegans,regulation of ubiquitin-protein transferase activity [GO:0051438] comp141617_c2_seq4,1892,37.0507,0.49442258,0,0,,7.00E-20,P21541,Early embryogenesis protein zyg-11,Early embryogenesis protein zyg-11,GO:0008595; GO:0008054; GO:0009792; GO:0007138; GO:0051759,"anterior/posterior axis specification, embryo; cyclin catabolic process; embryo development ending in birth or egg hatching; meiotic anaphase II; sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation",,,,,,,,,,ZYG11_CAEEL,Caenorhabditis elegans,"anterior/posterior axis specification, embryo [GO:0008595]; embryo development ending in birth or egg hatching [GO:0009792]; meiotic nuclear division [GO:0007126]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; positive regulation of metaphase/anaphase transition of meiotic cell cycle [GO:1902104]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of ubiquitin-protein transferase activity [GO:0051438]; sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation [GO:0051759]" comp141617_c2_seq5,2112,36.3163,0.47031993,4,31,,4.00E-66,Q2WF59,Zyg eleven-related protein 1 (zyg-11-related protein),Zyg eleven-related protein 1 (zyg-11-related protein),GO:0031462; GO:0051438; GO:0004842,Cul2-RING ubiquitin ligase complex; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,,,,,,,,,,ZER1_CAEEL,Caenorhabditis elegans,regulation of ubiquitin-protein transferase activity [GO:0051438] comp141617_c2_seq8,1672,37.4402,0.51100667,3,15,,9.00E-73,Q9W0E8,Protein zer-1 homolog (Zyg-11 homolog B-like protein),Protein zer-1 homolog (Zyg-11 homolog B-like protein),GO:0031462; GO:0051438; GO:0004842,Cul2-RING ubiquitin ligase complex; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,,,,9.00E-11,ruditapes_c15361,,,,,ZER1_DROME,Drosophila melanogaster (Fruit fly),regulation of ubiquitin-protein transferase activity [GO:0051438] comp141621_c0_seq2,1670,43.2335,0.53089989,86,159,,1.00E-84,Q02790,"Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]","Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]",GO:0005524; GO:0005528; GO:0005525; GO:0030521; GO:0044295; GO:0061077; GO:0006825; GO:0005829; GO:0007566; GO:0046661; GO:0016020; GO:0005874; GO:0005739; GO:0031115; GO:0031111; GO:0010977; GO:0043025; GO:0005634; GO:0003755; GO:0048471; GO:0030850; GO:0030674; GO:0031503; GO:0006463,"ATP binding; FK506 binding; GTP binding; androgen receptor signaling pathway; axonal growth cone; chaperone-mediated protein folding; copper ion transport; cytosol; embryo implantation; male sex differentiation; membrane; microtubule; mitochondrion; negative regulation of microtubule polymerization; negative regulation of microtubule polymerization or depolymerization; negative regulation of neuron projection development; neuronal cell body; nucleus; peptidyl-prolyl cis-trans isomerase activity; perinuclear region of cytoplasm; prostate gland development; protein binding, bridging; protein complex localization; steroid hormone receptor complex assembly",PF00254;PF00515;PF07719;,,,,,,,,,FKBP4_HUMAN,Homo sapiens (Human),androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein complex localization [GO:0031503]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463] comp141622_c1_seq2,1996,42.7355,0.32290141,166,475,,1.00E-53,Q0IJ01,Protein zwilch homolog,Protein zwilch homolog,GO:0051301; GO:0000777; GO:0007067; GO:0007093,cell division; condensed chromosome kinetochore; mitosis; mitotic cell cycle checkpoint,PF09817;,,,,,,,,,ZWILC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067] comp141622_c2_seq1,1663,40.7096,0.85696859,174,844,,7.00E-68,P25961,Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor),Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor),GO:0007189; GO:0007568; GO:0016324; GO:0016323; GO:0030282; GO:0045453; GO:0031526; GO:0048469; GO:0002062; GO:0005737; GO:0007204; GO:0005887; GO:0008285; GO:0005634; GO:0002076; GO:0004991; GO:0017046; GO:0007200; GO:0008284; GO:0060732; GO:0043235,adenylate cyclase-activating G-protein coupled receptor signaling pathway; aging; apical plasma membrane; basolateral plasma membrane; bone mineralization; bone resorption; brush border membrane; cell maturation; chondrocyte differentiation; cytoplasm; elevation of cytosolic calcium ion concentration; integral to plasma membrane; negative regulation of cell proliferation; nucleus; osteoblast development; parathyroid hormone receptor activity; peptide hormone binding; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of cell proliferation; positive regulation of inositol phosphate biosynthetic process; receptor complex,PF00002;PF02793;,2.00E-14,CHOYP_PTH1R.4.4,,,,,,,PTH1R_RAT,Rattus norvegicus (Rat),"adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; aging [GO:0007568]; bone mineralization [GO:0030282]; bone resorption [GO:0045453]; cell maturation [GO:0048469]; cell surface receptor signaling pathway [GO:0007166]; chondrocyte differentiation [GO:0002062]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of cell proliferation [GO:0008285]; osteoblast development [GO:0002076]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of inositol phosphate biosynthetic process [GO:0060732]" comp141624_c1_seq1,3578,41.308,0.33659737,164,877,,2.00E-138,Q96KP1,Exocyst complex component 2 (Exocyst complex component Sec5),Exocyst complex component 2 (Exocyst complex component Sec5),GO:0044267; GO:0006887; GO:0005886; GO:0015031,cellular protein metabolic process; exocytosis; plasma membrane; protein transport,PF01833;,3.00E-137,CHOYP_EXOC2.3.3,,,,,,,EXOC2_HUMAN,Homo sapiens (Human),exocyst assembly [GO:0001927]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]; regulation of entry of bacterium into host cell [GO:2000535] comp141624_c1_seq2,2751,43.8023,0.37442806,5,21,,1.00E-22,Q54VX5,Exocyst complex component 2 (Exocyst complex component Sec5),Exocyst complex component 2 (Exocyst complex component Sec5),GO:0006887; GO:0015031; GO:0007165,exocytosis; protein transport; signal transduction,,2.00E-137,CHOYP_EXOC2.3.3,,,,,,,EXOC2_DICDI,Dictyostelium discoideum (Slime mold),exocyst assembly [GO:0001927]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]; signal transduction [GO:0007165] comp141625_c0_seq1,1894,42.1859,0.35789842,120,11,,5.00E-27,Q504Y3,Zinc finger CW-type PWWP domain protein 2,Zinc finger CW-type PWWP domain protein 2,GO:0008270,zinc ion binding,PF00855;PF07496;,,,,,,,,,ZCPW2_HUMAN,Homo sapiens (Human), comp141625_c0_seq2,816,44.7304,0.370287,4,0,,4.00E-15,Q9H0M4,Zinc finger CW-type PWWP domain protein 1,Zinc finger CW-type PWWP domain protein 1,GO:0008270,zinc ion binding,PF00855;PF07496;,,,,,,,,,ZCPW1_HUMAN,Homo sapiens (Human), comp141625_c0_seq5,332,46.988,0.21897289,0,0,,1.00E-14,Q08EN7,Zinc finger CW-type PWWP domain protein 2 homolog,Zinc finger CW-type PWWP domain protein 2 homolog,GO:0008270,zinc ion binding,PF07496;,,,,,,,,,ZCPW2_MOUSE,Mus musculus (Mouse), comp141625_c0_seq7,538,45.3532,0.1822923,2,0,,6.00E-29,Q504Y3,Zinc finger CW-type PWWP domain protein 2,Zinc finger CW-type PWWP domain protein 2,GO:0008270,zinc ion binding,PF00855;PF07496;,,,,,,,,,ZCPW2_HUMAN,Homo sapiens (Human), comp141626_c0_seq1,1117,41.0027,0.55637905,431,938,,2.00E-21,Q91WE2,Protein FAM192A (NEFA-interacting nuclear protein NIP30),Protein FAM192A (NEFA-interacting nuclear protein NIP30),GO:0005634,nucleus,PF10187;,,,,,,,,,F192A_MOUSE,Mus musculus (Mouse), comp141627_c1_seq11,649,29.4299,0.71272099,52,109,,,,,,,,,,,2.00E-13,ruditapes_lrc23864,,,,,,, comp141629_c0_seq2,2310,30.0866,0.48083334,0,0,,,,,,,,,,,5.00E-16,ruditapes_c22334,,,,,,, comp141631_c0_seq13,433,42.9561,0.3013905,0,0,,1.00E-10,A0JMF7,HAUS augmin-like complex subunit 6,HAUS augmin-like complex subunit 6,GO:0070652; GO:0051301; GO:0051297; GO:0005737; GO:0005874; GO:0005815; GO:0007067; GO:0005819; GO:0051225,HAUS complex; cell division; centrosome organization; cytoplasm; microtubule; microtubule organizing center; mitosis; spindle; spindle assembly,PF14661;,,,,,,,,,HAUS6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp141631_c0_seq3,1534,44.0026,0.44669331,16,35,,,,,,,,,3.00E-12,CHOYP_TRIADDRAFT_54602.1.1,,,,,,,,, comp141631_c0_seq5,580,42.7586,0.30278248,6,18,,9.00E-21,Q7Z4H7,HAUS augmin-like complex subunit 6,HAUS augmin-like complex subunit 6,GO:0070652; GO:0051301; GO:0005813; GO:0051297; GO:0005737; GO:0005874; GO:0007067; GO:0005634; GO:0005819; GO:0051225,HAUS complex; cell division; centrosome; centrosome organization; cytoplasm; microtubule; mitosis; nucleus; spindle; spindle assembly,PF14661;,,,,,,,,,HAUS6_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp141631_c0_seq6,1896,44.0928,0.41740844,64,55,,,,,,,,,4.00E-12,CHOYP_TRIADDRAFT_54602.1.1,,,,,,,,, comp141632_c0_seq2,2151,34.821,0.27619651,23,189,,4.00E-63,Q3ZCJ2,Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1),Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1),GO:0008106,alcohol dehydrogenase (NADP+) activity,PF00248;,,,,,,,,,AK1A1_BOVIN,Bos taurus (Bovine),aldehyde catabolic process [GO:0046185]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853] comp141634_c0_seq2,2127,36.6714,0.60832754,0,0,,5.00E-51,B5X186,Calumenin-A,Calumenin-A,GO:0005509; GO:0005576; GO:0042470; GO:0033018,calcium ion binding; extracellular region; melanosome; sarcoplasmic reticulum lumen,PF13202;PF13833;,,,8.00E-32,ruditapes_c8482,,,,,CALUA_SALSA,Salmo salar (Atlantic salmon), comp141635_c0_seq1,316,44.3038,0.58995628,11,46,,,,,,,,,5.00E-14,CHOYP_LOC100369720.1.1,,,,,,,,, comp141637_c1_seq1,1463,36.9788,1.01598982,87,0,,9.00E-07,P81900,cAMP-dependent protein kinase type II regulatory subunit,cAMP-dependent protein kinase type II regulatory subunit,GO:0007411; GO:0048148; GO:0048149; GO:0030552; GO:0005952; GO:0008603; GO:0005737; GO:0045475,axon guidance; behavioral response to cocaine; behavioral response to ethanol; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; cytoplasm; locomotor rhythm,PF00027;,,,,,,,,,KAPR2_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; rhythmic behavior [GO:0007622] comp141637_c1_seq2,1450,36.8276,0.99507141,65,0,,5.00E-07,P12368,cAMP-dependent protein kinase type II-alpha regulatory subunit,cAMP-dependent protein kinase type II-alpha regulatory subunit,GO:0030315; GO:0030552; GO:0005952; GO:0008603; GO:0048471; GO:0019904; GO:0051291; GO:0042803; GO:0034236; GO:0097338,T-tubule; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; perinuclear region of cytoplasm; protein domain specific binding; protein heterooligomerization; protein homodimerization activity; protein kinase A catalytic subunit binding; response to clozapine,PF00027;PF02197;,,,,,,,,,KAP2_RAT,Rattus norvegicus (Rat),protein heterooligomerization [GO:0051291]; regulation of protein kinase activity [GO:0045859]; response to clozapine [GO:0097338] comp141640_c1_seq3,1082,37.8004,0.53135165,51,1172,,1.00E-22,O75954,Tetraspanin-9 (Tspan-9) (Tetraspan NET-5),Tetraspanin-9 (Tspan-9) (Tetraspan NET-5),GO:0005887,integral to plasma membrane,PF00335;,,,,,,,,,TSN9_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166] comp141641_c0_seq2,3145,43.0207,0.51116151,943,0,male,0,Q5T655,Coiled-coil domain-containing protein 147,Cilia- and flagella-associated protein 58 (Coiled-coil domain-containing protein 147),,,,0,CHOYP_LOC100366451.1.1,,,6.00E-78,CU685202.p.cg.6,5,,CC147_HUMAN,Homo sapiens (Human), comp141642_c0_seq1,1493,42.3979,0.86520528,242,218,,1.00E-25,P78348,"Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)","Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)",GO:0008306; GO:0070588; GO:0005887; GO:0015280; GO:0007613; GO:0046929; GO:0042391; GO:0001101; GO:0009268; GO:0007165; GO:0045202,associative learning; calcium ion transmembrane transport; integral to plasma membrane; ligand-gated sodium channel activity; memory; negative regulation of neurotransmitter secretion; regulation of membrane potential; response to acid; response to pH; signal transduction; synapse,PF00858;,,,,,,,,,ASIC1_HUMAN,Homo sapiens (Human),associative learning [GO:0008306]; calcium ion transmembrane transport [GO:0070588]; cellular response to pH [GO:0071467]; ion transmembrane transport [GO:0034220]; memory [GO:0007613]; negative regulation of neurotransmitter secretion [GO:0046929]; protein homotrimerization [GO:0070207]; regulation of membrane potential [GO:0042391]; response to acidic pH [GO:0010447]; response to pH [GO:0009268]; sensory perception of sour taste [GO:0050915]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transport [GO:0006810] comp141643_c0_seq3,303,43.8944,0.34467496,5,5,,4.00E-33,Q6GNY8,Transmembrane protein 39A-B,Transmembrane protein 39A-B,GO:0016021,integral to membrane,PF10271;,,,,,,,,,T39AB_XENLA,Xenopus laevis (African clawed frog), comp141643_c6_seq1,868,40.2074,0.4334891,31,55,,5.00E-36,Q6GL42,Transmembrane protein 39A,Transmembrane protein 39A,GO:0016021,integral to membrane,PF10271;,1.00E-45,CHOYP_TM39A.1.1,,,,,,,TM39A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141645_c0_seq1,1148,35.2787,0.11223452,5,6,,,,,,,,,1.00E-78,CHOYP_LOC594590.2.2,,,,,,,,, comp141645_c0_seq2,1171,34.842,0.1129204,11,66,,3.00E-69,B5XGE7,Trafficking protein particle complex subunit 2-like protein,Trafficking protein particle complex subunit 2-like protein,GO:0006888; GO:0005794; GO:0005783; GO:0048471,ER to Golgi vesicle-mediated transport; Golgi apparatus; endoplasmic reticulum; perinuclear region of cytoplasm,PF04628;,1.00E-78,CHOYP_LOC594590.2.2,,,,,,,TPC2L_SALSA,Salmo salar (Atlantic salmon),ER to Golgi vesicle-mediated transport [GO:0006888] comp141646_c0_seq1,1595,37.2414,0.4533423,4,58,,4.00E-17,Q99186,AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein),AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein),GO:0030122; GO:0006886; GO:0016192,AP-2 adaptor complex; intracellular protein transport; vesicle-mediated transport,PF00928;,,,,,,,,,AP2M_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] comp141646_c0_seq2,1924,38.3056,0.4396403,32,116,,0,Q5R478,AP-3 complex subunit mu-1 (AP-3 adapter complex mu3A subunit) (Adapter-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin),AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin),GO:0005794; GO:0008089; GO:0048490; GO:0030131; GO:0006886,Golgi apparatus; anterograde axon cargo transport; anterograde synaptic vesicle transport; clathrin adaptor complex; intracellular protein transport,PF00928;PF01217;,0,CHOYP_AP3M2.1.1,,,,,,,AP3M1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886] comp141646_c1_seq1,206,33.9806,0.17121992,2,29,,,,,,,,,2.00E-24,CHOYP_AP3M1.1.1,,,,,,,,, comp141647_c0_seq1,8342,46.4397,0.57550878,319,558,,0,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,0,CHOYP_SPTCA.2.2,3.00E-25,ruditapes2_c1588,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp141647_c0_seq2,4259,49.0726,0.56529872,3,10,,3.00E-140,Q62261,"Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)","Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)",GO:0043001; GO:0031430; GO:0007184; GO:0051693; GO:0030673; GO:0007182; GO:0032437; GO:0071709; GO:0000281; GO:0005730; GO:0005634; GO:0005543; GO:0072661; GO:0008091; GO:0005200,Golgi to plasma membrane protein transport; M band; SMAD protein import into nucleus; actin filament capping; axolemma; common-partner SMAD protein phosphorylation; cuticular plate; membrane assembly; mitotic cytokinesis; nucleolus; nucleus; phospholipid binding; protein targeting to plasma membrane; spectrin; structural constituent of cytoskeleton,PF00307;PF00435;,0,CHOYP_SPTCA.1.2,,,,,,,SPTB2_MOUSE,Mus musculus (Mouse),actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184] comp141647_c0_seq3,4343,49.1826,0.57796755,13,22,,2.00E-109,Q9QWN8,"Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)","Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)",GO:0051693; GO:0005829; GO:0016363; GO:0005543; GO:0017158; GO:0008091; GO:0005200; GO:0016081,actin filament capping; cytosol; nuclear matrix; phospholipid binding; regulation of calcium ion-dependent exocytosis; spectrin; structural constituent of cytoskeleton; synaptic vesicle docking involved in exocytosis,PF00307;PF00435;,,,,,,,,,SPTN2_RAT,Rattus norvegicus (Rat),actin filament capping [GO:0051693]; cellular response to ethanol [GO:0071361]; regulation of calcium ion-dependent exocytosis [GO:0017158]; synaptic vesicle docking [GO:0016081]; synaptic vesicle exocytosis [GO:0016079] comp141647_c0_seq4,8356,46.4816,0.57366521,233,797,,0,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,,,,,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp141648_c0_seq1,4430,46.8849,0.38100955,11,0,,9.00E-07,Q8TCU4,Alstrom syndrome protein 1,Alstrom syndrome protein 1,GO:0000086; GO:0005813; GO:0005929; GO:0005829; GO:0016197; GO:0005932; GO:0051492; GO:0000922,G2/M transition of mitotic cell cycle; centrosome; cilium; cytosol; endosomal transport; microtubule basal body; regulation of stress fiber assembly; spindle pole,PF15309;,,,,,,,,,ALMS1_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of stress fiber assembly [GO:0051492] comp141648_c0_seq2,4397,46.7137,0.38238767,2,11,,8.00E-07,Q8K4E0,Alstrom syndrome protein 1 homolog,Alstrom syndrome protein 1 homolog,GO:0005814; GO:0005929; GO:0016197; GO:0005932; GO:0051492; GO:0000922,centriole; cilium; endosomal transport; microtubule basal body; regulation of stress fiber assembly; spindle pole,PF15309;,,,,,,,,,ALMS1_MOUSE,Mus musculus (Mouse),calcium-mediated signaling [GO:0019722]; cellular glucose homeostasis [GO:0001678]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0042384]; endosomal transport [GO:0016197]; epithelial cell proliferation [GO:0050673]; establishment of planar polarity [GO:0001736]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; inner ear receptor stereocilium organization [GO:0060122]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; ovulation [GO:0030728]; regulation of fat cell differentiation [GO:0045598]; regulation of stress fiber assembly [GO:0051492]; retinal rod cell development [GO:0046548]; sensory perception of sound [GO:0007605]; spermatid development [GO:0007286] comp14164_c0_seq1,215,44.6512,0.28235905,3,3,,2.00E-13,Q8R1Q8,"Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)","Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)",GO:0005524; GO:0051301; GO:0005813; GO:0000777; GO:0005868; GO:0000776; GO:0005874; GO:0003777; GO:0007018; GO:0007067; GO:0005886; GO:0090267; GO:0000922; GO:0006810,ATP binding; cell division; centrosome; condensed chromosome kinetochore; cytoplasmic dynein complex; kinetochore; microtubule; microtubule motor activity; microtubule-based movement; mitosis; plasma membrane; positive regulation of mitotic cell cycle spindle assembly checkpoint; spindle pole; transport,PF05783;,,,,,,,,,DC1L1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; transport [GO:0006810] comp141652_c2_seq1,3216,39.3035,0.24326984,0,0,,6.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq10,1478,39.3775,0.36950383,0,0,,8.00E-11,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp141652_c2_seq11,3768,39.7293,0.24996058,0,0,,7.00E-70,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq12,3256,39.4656,0.26218462,0,0,,4.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq14,4606,39.2749,0.27234908,0,0,,6.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq19,3780,39.6825,0.24981609,0,0,,7.00E-70,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq2,4495,39.2881,0.27315233,0,0,,2.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq22,4538,39.7091,0.28759543,0,0,,2.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq26,4518,39.3537,0.27658987,0,0,,4.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq27,2697,39.0434,0.30260867,0,0,,6.00E-71,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq29,2735,39.5978,0.30909966,0,0,,6.00E-71,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq31,4691,39.5864,0.27999486,0,0,,4.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq33,4618,39.2378,0.27222766,0,0,,3.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq36,1528,40.2487,0.37586053,0,0,,9.00E-11,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp141652_c2_seq39,3335,39.5202,0.2782061,0,0,,3.00E-70,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq40,4568,39.6454,0.28106892,0,0,,4.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq42,4500,39.3778,0.2831501,0,0,,2.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq44,4550,39.6703,0.2874793,0,0,,1.00E-26,Q6ZNL0,"GPS, PLAT and transmembrane domain-containing protein FLJ00285",,GO:0016021; GO:0007218,integral to membrane; neuropeptide signaling pathway,,,,,,,,,,YP009_HUMAN,, comp141652_c2_seq47,4002,39.955,0.25167001,0,0,,1.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq49,4585,39.6947,0.29057006,0,0,,6.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq5,4545,39.582,0.277762,0,0,,3.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq51,3952,39.6255,0.24593598,0,0,,1.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq54,4573,39.7332,0.2906853,0,0,,3.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq57,3244,39.5191,0.26234945,0,0,,3.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq59,2747,39.534,0.308844,0,0,,7.00E-71,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq63,3830,40.0261,0.25569286,0,0,,8.00E-70,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq64,4014,39.9103,0.25154082,0,0,,1.00E-15,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq65,4483,39.3263,0.27327638,0,0,,6.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq68,2685,39.1061,0.30290005,0,0,,5.00E-71,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq69,2006,39.0329,0.22310213,0,0,,5.00E-25,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq71,3374,39.2709,0.24780534,0,0,,4.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq75,3964,39.5812,0.24579522,0,0,,1.00E-15,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq76,3273,39.169,0.27214499,0,0,,2.00E-70,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq77,4533,39.6206,0.27787598,0,0,,2.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq79,1769,37.0831,0.32956302,1298,140,,2.00E-39,Q4GZT3,Polycystin-2 (Polycystic kidney disease 2 protein homolog),Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2),GO:0007259; GO:0035904; GO:0045180; GO:0009925; GO:0001658; GO:0005262; GO:0005509; GO:0048763; GO:0007050; GO:0005911; GO:0071498; GO:0071464; GO:0071470; GO:0042994; GO:0050982; GO:0003127; GO:0071910; GO:0001892; GO:0031941; GO:0001947; GO:0071458; GO:0071556; GO:0005887; GO:0030027; GO:0016020; GO:0072177; GO:0072284; GO:0072218; GO:0072214; GO:0072219; GO:0072235; GO:0072075; GO:0035502; GO:0072208; GO:0005932; GO:0072686; GO:0031512; GO:2000134; GO:0060315; GO:0021915; GO:0031513; GO:0060674; GO:0002133; GO:0071158; GO:0031659; GO:0031587; GO:0045429; GO:0045944; GO:0005267; GO:0030814; GO:0090279; GO:0042127; GO:0051209; GO:0061441; GO:0061333; GO:0021510; GO:0005245; GO:0005248,"JAK-STAT cascade; aorta development; basal cortex; basal plasma membrane; branching involved in ureteric bud morphogenesis; calcium channel activity; calcium ion binding; calcium-induced calcium release activity; cell cycle arrest; cell-cell junction; cellular response to fluid shear stress; cellular response to hydrostatic pressure; cellular response to osmotic stress; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; detection of nodal flow; determination of liver left/right asymmetry; embryonic placenta development; filamentous actin; heart looping; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; lamellipodium; membrane; mesonephric duct development; metanephric S-shaped body morphogenesis; metanephric ascending thin limb development; metanephric cortex development; metanephric cortical collecting duct development; metanephric distal tubule development; metanephric mesenchyme development; metanephric part of ureteric bud development; metanephric smooth muscle tissue development; microtubule basal body; mitotic spindle; motile primary cilium; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of ryanodine-sensitive calcium-release channel activity; neural tube development; nonmotile primary cilium; placenta blood vessel development; polycystin complex; positive regulation of cell cycle arrest; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of nitric oxide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; potassium channel activity; regulation of cAMP metabolic process; regulation of calcium ion import; regulation of cell proliferation; release of sequestered calcium ion into cytosol; renal artery morphogenesis; renal tubule morphogenesis; spinal cord development; voltage-gated calcium channel activity; voltage-gated sodium channel activity",PF08016;,,,,,,,,,PKD2_BOVIN,Bos taurus (Bovine),"aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]" comp141652_c2_seq82,2685,39.7393,0.19856376,0,0,,6.00E-16,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq83,3323,39.5727,0.27838162,0,0,,3.00E-70,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq89,4488,39.4162,0.28327677,0,0,,2.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141652_c2_seq90,4530,39.3157,0.27646664,0,0,,3.00E-69,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141653_c1_seq1,2927,41.5784,0.47150811,422,2720,,0,Q9UNX4,WD repeat-containing protein 3,WD repeat-containing protein 3,GO:0031965; GO:0005730,nuclear membrane; nucleolus,PF12894;PF04003;PF00400;,1.00E-166,CHOYP_BRAFLDRAFT_114488.1.1,4.00E-75,ruditapes_c24014,,,,,WDR3_HUMAN,Homo sapiens (Human),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]" comp141654_c0_seq1,2893,43.8991,0.37863479,22,209,,0,Q05BC3,Echinoderm microtubule-associated protein-like 1 (EMAP-1),Echinoderm microtubule-associated protein-like 1 (EMAP-1),GO:0005737; GO:0005874,cytoplasm; microtubule,PF03451;PF00400;,7.00E-87,CHOYP_EMAL1.1.1,,,,,,,EMAL1_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; hematopoietic progenitor cell differentiation [GO:0002244]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neuroblast proliferation [GO:0007405] comp141654_c0_seq2,2757,44.4686,0.3727098,0,17,,0,Q05BC3,Echinoderm microtubule-associated protein-like 1 (EMAP-1),Echinoderm microtubule-associated protein-like 1 (EMAP-1),GO:0005737; GO:0005874,cytoplasm; microtubule,PF03451;PF00400;,7.00E-87,CHOYP_EMAL1.1.1,,,,,,,EMAL1_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; hematopoietic progenitor cell differentiation [GO:0002244]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neuroblast proliferation [GO:0007405] comp141655_c1_seq1,1591,42.049,0.69762119,33,126,,0,Q66I21,Aldehyde dehydrogenase family 8 member A1 (EC 1.2.1.-),Aldehyde dehydrogenase family 8 member A1 (EC 1.2.1.-),GO:0005737; GO:0001889; GO:0016620,"cytoplasm; liver development; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",PF00171;,1.00E-86,CHOYP_AL8A1.1.1,,,,,,,AL8A1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),liver development [GO:0001889] comp141655_c1_seq2,709,39.2102,0.84794697,22,221,,7.00E-43,Q29491,"Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)","Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)",GO:0004029; GO:0005737; GO:0006068,aldehyde dehydrogenase (NAD) activity; cytoplasm; ethanol catabolic process,PF00171;,,,,,,,,,ALDH2_MACPR,Macroscelides proboscideus (Short-eared elephant shrew),ethanol catabolic process [GO:0006068] comp141655_c1_seq3,928,44.5043,0.61669109,3,0,,2.00E-15,P86808,Limonin dehydrogenase (EC 1.2.1.-) (Fragments),Limonin dehydrogenase (EC 1.2.1.-) (Fragments),GO:0016491; GO:0042597,oxidoreductase activity; periplasmic space,PF00171;,3.00E-54,CHOYP_CTL2.1.2,,,,,,,LMDH_PSEPU,Pseudomonas putida (Arthrobacter siderocapsulatus), comp141659_c2_seq1,1332,39.6396,0.30687787,261,1134,,3.00E-12,Q9NVX0,HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27),HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27),GO:0000086; GO:0005794; GO:0070652; GO:0051301; GO:0005813; GO:0051297; GO:0005829; GO:0005874; GO:0007067; GO:0005634; GO:0005819; GO:0051225,G2/M transition of mitotic cell cycle; Golgi apparatus; HAUS complex; cell division; centrosome; centrosome organization; cytosol; microtubule; mitosis; nucleus; spindle; spindle assembly,PF15003;,,,,,,,,,HAUS2_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp141660_c1_seq1,342,47.3684,0,7,6,,,,,,,,,5.00E-21,CHOYP_contig_051198,,,,,,,,, comp141662_c0_seq1,1775,37.6338,0.39990285,110,208,,3.00E-18,P52709,"Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)","Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)",GO:0005524; GO:0005737; GO:0008340; GO:0004829; GO:0006435,ATP binding; cytoplasm; determination of adult lifespan; threonine-tRNA ligase activity; threonyl-tRNA aminoacylation,PF03129;PF02824;PF00587;PF07973;,,,,,,,,,SYTC_CAEEL,Caenorhabditis elegans,determination of adult lifespan [GO:0008340]; threonyl-tRNA aminoacylation [GO:0006435] comp141662_c0_seq2,1787,37.437,0.4013145,20,209,,4.00E-81,Q9VUJ0,"39S ribosomal protein L39, mitochondrial (MRP-L39) (MRP-L5)","39S ribosomal protein L39, mitochondrial (MRP-L39) (MRP-L5)",GO:0031047; GO:0005762; GO:0000166; GO:0006417; GO:0003735; GO:0006412,gene silencing by RNA; mitochondrial large ribosomal subunit; nucleotide binding; regulation of translation; structural constituent of ribosome; translation,,,,,,,,,,RM39_DROME,Drosophila melanogaster (Fruit fly),gene silencing by RNA [GO:0031047]; mitochondrial genome maintenance [GO:0000002]; regulation of translation [GO:0006417]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418] comp141664_c0_seq1,3929,33.0618,0.48078587,395,2390,,2.00E-87,Q28735,Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1),Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1),GO:0030137; GO:0035964; GO:0007030; GO:0034205; GO:0005789; GO:0033116; GO:0070765; GO:0016021; GO:0006886; GO:0042470; GO:0045055; GO:0006890; GO:0030667; GO:0030140; GO:0030658,"COPI-coated vesicle; COPI-coated vesicle budding; Golgi organization; beta-amyloid formation; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; gamma-secretase complex; integral to membrane; intracellular protein transport; melanosome; regulated secretory pathway; retrograde vesicle-mediated transport, Golgi to ER; secretory granule membrane; trans-Golgi network transport vesicle; transport vesicle membrane",PF01105;,8.00E-120,CHOYP_TMEDA.2.2,,,,,,,TMEDA_RABIT,Oryctolagus cuniculus (Rabbit),"COPI-coated vesicle budding [GO:0035964]; protein transport [GO:0015031]; regulation of beta-amyloid formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp141664_c0_seq2,3967,33.0981,0.48401598,589,2488,,2.00E-87,Q28735,Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1),Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1),GO:0030137; GO:0035964; GO:0007030; GO:0034205; GO:0005789; GO:0033116; GO:0070765; GO:0016021; GO:0006886; GO:0042470; GO:0045055; GO:0006890; GO:0030667; GO:0030140; GO:0030658,"COPI-coated vesicle; COPI-coated vesicle budding; Golgi organization; beta-amyloid formation; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; gamma-secretase complex; integral to membrane; intracellular protein transport; melanosome; regulated secretory pathway; retrograde vesicle-mediated transport, Golgi to ER; secretory granule membrane; trans-Golgi network transport vesicle; transport vesicle membrane",PF01105;,,,3.00E-161,ruditapes_c7905,,,,,TMEDA_RABIT,Oryctolagus cuniculus (Rabbit),"COPI-coated vesicle budding [GO:0035964]; protein transport [GO:0015031]; regulation of beta-amyloid formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp141666_c0_seq1,1742,35.4191,0.46399836,16,299,,4.00E-48,Q55FU2,Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP),Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP),GO:0030126; GO:0006891; GO:0015031; GO:0006890; GO:0005198,"COPI vesicle coat; intra-Golgi vesicle-mediated transport; protein transport; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",,,,,,,,,,COPE_DICDI,Dictyostelium discoideum (Slime mold),"ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp141666_c0_seq3,1660,35.5422,0.42589759,8,73,,2.00E-147,Q5ZIK9,Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP),Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP),GO:0030663; GO:0015031; GO:0006890; GO:0005198,"COPI-coated vesicle membrane; protein transport; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",,3.00E-114,CHOYP_COPE.1.1,9.00E-100,ruditapes2_c2660,,,,,COPE_CHICK,Gallus gallus (Chicken),"ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp141667_c0_seq1,1134,35.8025,0.88213218,291,1706,,,,,,,,,4.00E-15,CHOYP_LOC100080726.1.1,,,,,,,,, comp141667_c0_seq2,1630,41.7791,1.19114758,187,975,,6.00E-40,Q5D1E7,Ribonuclease ZC3H12A (EC 3.1.-.-) (MCP-induced protein 1) (Zinc finger CCCH domain-containing protein 12A),Bifunctional endoribonuclease and deubiquitinase ZC3H12A [Includes: Endoribonuclease ZC3H12A (EC 3.1.-.-); Deubiquitinase ZC3H12A (EC 3.4.19.12) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A)],GO:0001525; GO:0006915; GO:0030154; GO:0071222; GO:0005737; GO:0004519; GO:0046872; GO:0032088; GO:0010629; GO:0032715; GO:0045019; GO:0032720; GO:0090305; GO:0005634; GO:0005886; GO:0010508; GO:0045600; GO:0010628; GO:0010884; GO:2000379,angiogenesis; apoptotic process; cell differentiation; cellular response to lipopolysaccharide; cytoplasm; endonuclease activity; metal ion binding; negative regulation of NF-kappaB transcription factor activity; negative regulation of gene expression; negative regulation of interleukin-6 production; negative regulation of nitric oxide biosynthetic process; negative regulation of tumor necrosis factor production; nucleic acid phosphodiester bond hydrolysis; nucleus; plasma membrane; positive regulation of autophagy; positive regulation of fat cell differentiation; positive regulation of gene expression; positive regulation of lipid storage; positive regulation of reactive oxygen species metabolic process,PF11977;,,,,,,,,,ZC12A_MOUSE,Mus musculus (Mouse),"3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; immune system process [GO:0002376]; inflammatory response [GO:0006954]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deubiquitination [GO:0016579]; protein oligomerization [GO:0051259]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" comp141668_c0_seq1,1971,35.2106,0.37971345,65,244,,5.00E-08,Q01369,Guanine nucleotide-binding protein subunit beta-like protein (Cross-pathway control WD-repeat protein cpc-2),Guanine nucleotide-binding protein subunit beta-like protein (Cross-pathway control WD-repeat protein cpc-2),,,PF00400;,,,,,,,,,GBLP_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),cellular protein localization [GO:0034613]; conjugation with cellular fusion [GO:0000747]; intracellular signal transduction [GO:0035556]; positive regulation of conjugation with cellular fusion [GO:0031139]; positive regulation of protein autophosphorylation [GO:0031954]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of fungal-type cell wall biogenesis [GO:0032995] comp141668_c0_seq2,2413,35.4331,0.43757354,94,482,,5.00E-157,Q5ZMV7,WD repeat-containing protein 82,WD repeat-containing protein 82,GO:0072357; GO:0048188; GO:0000785; GO:0003682; GO:0042800,PTW/PP1 phosphatase complex; Set1C/COMPASS complex; chromatin; chromatin binding; histone methyltransferase activity (H3-K4 specific),PF00400;,2.00E-168,CHOYP_LOC654994.1.1,,,,,,,WDR82_CHICK,Gallus gallus (Chicken), comp141670_c0_seq1,2844,37.7637,1.08086254,987,5999,,3.00E-93,Q8SPK0,Cytochrome P450 4A25 (CYPIVA25) (Fatty acid omega-hydroxylase) (EC 1.14.15.3),Cytochrome P450 4A25 (CYPIVA25) (Fatty acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.13.205),GO:0018685; GO:0052869; GO:0005789; GO:0020037; GO:0016021; GO:0005506,alkane 1-monooxygenase activity; arachidonic acid omega-hydroxylase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,2.00E-16,ruditapes2_c2019,,,,,CP4AP_PIG,Sus scrofa (Pig), comp141673_c0_seq2,486,43.2099,0.44860175,2,0,,3.00E-17,P07602,Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)],Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)],GO:0005794; GO:0071310; GO:0008047; GO:0060742; GO:0005615; GO:0006687; GO:0016021; GO:0008289; GO:0006869; GO:0043202; GO:0005765; GO:0005739; GO:0030168; GO:0002576; GO:0060736; GO:0043408; GO:0019216; GO:0044281,Golgi apparatus; cellular response to organic substance; enzyme activator activity; epithelial cell differentiation involved in prostate gland development; extracellular space; glycosphingolipid metabolic process; integral to membrane; lipid binding; lipid transport; lysosomal lumen; lysosomal membrane; mitochondrion; platelet activation; platelet degranulation; prostate gland growth; regulation of MAPK cascade; regulation of lipid metabolic process; small molecule metabolic process,PF02199;PF05184;PF03489;,,,,,,,,,SAP_HUMAN,Homo sapiens (Human),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; platelet degranulation [GO:0002576]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216] comp141673_c0_seq3,489,42.1268,0.41820943,6,5,,2.00E-06,P15781,Pulmonary surfactant-associated protein B (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)),Pulmonary surfactant-associated protein B (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)),GO:0005615; GO:0005764; GO:0007585; GO:0006665,extracellular space; lysosome; respiratory gaseous exchange; sphingolipid metabolic process,PF02199;PF05184;PF03489;,,,,,,,,,PSPB_BOVIN,Bos taurus (Bovine),organ morphogenesis [GO:0009887]; respiratory gaseous exchange [GO:0007585]; sphingolipid metabolic process [GO:0006665] comp141673_c0_seq5,1028,45.5253,0.47362652,132,187,,7.00E-30,P07602,Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)],Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)],GO:0005794; GO:0071310; GO:0008047; GO:0060742; GO:0005615; GO:0006687; GO:0016021; GO:0008289; GO:0006869; GO:0043202; GO:0005765; GO:0005739; GO:0030168; GO:0002576; GO:0060736; GO:0043408; GO:0019216; GO:0044281,Golgi apparatus; cellular response to organic substance; enzyme activator activity; epithelial cell differentiation involved in prostate gland development; extracellular space; glycosphingolipid metabolic process; integral to membrane; lipid binding; lipid transport; lysosomal lumen; lysosomal membrane; mitochondrion; platelet activation; platelet degranulation; prostate gland growth; regulation of MAPK cascade; regulation of lipid metabolic process; small molecule metabolic process,PF02199;PF05184;PF03489;,,,,,,,,,SAP_HUMAN,Homo sapiens (Human),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; platelet degranulation [GO:0002576]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216] comp141673_c0_seq8,480,44.7917,0.50000217,2,28,,2.00E-09,P20097,Saposin-C (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2),Saposin-C (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2),GO:0005764; GO:0006665,lysosome; sphingolipid metabolic process,PF05184;PF03489;,,,,,,,,,SAP_CAVPO,Cavia porcellus (Guinea pig),sphingolipid metabolic process [GO:0006665] comp141674_c0_seq1,6128,44.2396,0.52569982,81,189,,0,P13541,Myosin-3 (Myosin heavy chain 3),Myosin-3 (Myosin heavy chain 3),GO:0005524; GO:0043292; GO:0003774; GO:0030016; GO:0016459; GO:0032982,ATP binding; contractile fiber; motor activity; myofibril; myosin complex; myosin filament,PF00063;PF02736;PF01576;,0,CHOYP_LOC100649130.1.1,2.00E-177,ruditapes2_c3140,,,,,MYH3_MOUSE,Mus musculus (Mouse),ATP metabolic process [GO:0046034]; skeletal muscle contraction [GO:0003009] comp141674_c0_seq2,6151,44.2205,0.52388046,225,33,,0,Q61879,"Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)","Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)",GO:0005524; GO:0007512; GO:0030424; GO:0007411; GO:0055003; GO:0005938; GO:0008283; GO:0021680; GO:0005829; GO:0043197; GO:0006887; GO:0021592; GO:0030426; GO:0001701; GO:0021670; GO:0000281; GO:0003774; GO:0016460; GO:0050885; GO:0001764; GO:0043025; GO:0007097; GO:0001778; GO:0008360; GO:0060041; GO:0001725; GO:0006930; GO:0021678; GO:0055015,"ATP binding; adult heart development; axon; axon guidance; cardiac myofibril assembly; cell cortex; cell proliferation; cerebellar Purkinje cell layer development; cytosol; dendritic spine; exocytosis; fourth ventricle development; growth cone; in utero embryonic development; lateral ventricle development; mitotic cytokinesis; motor activity; myosin II complex; neuromuscular process controlling balance; neuron migration; neuronal cell body; nuclear migration; plasma membrane repair; regulation of cell shape; retina development in camera-type eye; stress fiber; substrate-dependent cell migration, cell extension; third ventricle development; ventricular cardiac muscle cell development",PF00612;PF00063;PF02736;PF01576;,5.00E-143,CHOYP_ZIP.1.1,2.00E-83,ruditapes2_c5101,,,,,MYH10_MOUSE,Mus musculus (Mouse),"actin cytoskeleton organization [GO:0030036]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; adult heart development [GO:0007512]; aorta development [GO:0035904]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cardiac myofibril assembly [GO:0055003]; cardiac septum development [GO:0003279]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cerebellar Purkinje cell layer development [GO:0021680]; coronary vasculature development [GO:0060976]; exocytosis [GO:0006887]; fourth ventricle development [GO:0021592]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; lateral ventricle development [GO:0021670]; mitotic cytokinesis [GO:0000281]; myofibril assembly [GO:0030239]; neuromuscular process controlling balance [GO:0050885]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; nuclear migration [GO:0007097]; plasma membrane repair [GO:0001778]; regulation of cell shape [GO:0008360]; retina development in camera-type eye [GO:0060041]; substrate-dependent cell migration, cell extension [GO:0006930]; third ventricle development [GO:0021678]; ventricular cardiac muscle cell development [GO:0055015]" comp141676_c1_seq1,521,37.428,0.33692035,0,0,,7.00E-09,Q02499,Pyruvate kinase (PK) (EC 2.7.1.40),Pyruvate kinase (PK) (EC 2.7.1.40),GO:0005524; GO:0006096; GO:0000287; GO:0030955; GO:0004743,ATP binding; glycolysis; magnesium ion binding; potassium ion binding; pyruvate kinase activity,PF00391;PF00224;PF02887;,,,,,,,,,KPYK_GEOSE,Geobacillus stearothermophilus (Bacillus stearothermophilus), comp141676_c1_seq10,2416,41.0596,0.5079992,0,0,,3.00E-31,O34309,"Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)","Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)",GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,,,,,,,,,PPS_BACSU,Bacillus subtilis (strain 168), comp141676_c1_seq12,1284,41.3551,0.49877834,0,0,,1.00E-25,Q57962,"Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase) [Cleaved into: Mja pep intein (Mja pepA intein)]","Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase) [Cleaved into: Mja pep intein (Mja pepA intein)]",GO:0005524; GO:0004519; GO:0006094; GO:0016539; GO:0046872; GO:0008986,"ATP binding; endonuclease activity; gluconeogenesis; intein-mediated protein splicing; metal ion binding; pyruvate, water dikinase activity",PF00391;PF02896;PF01326;,,,,,,,,,PPSA_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),gluconeogenesis [GO:0006094]; intein-mediated protein splicing [GO:0016539] comp141676_c1_seq2,1017,42.7729,0.50184376,0,0,,,,,,,,,3.00E-30,CHOYP_LOC100890479.1.3,,,,,,,,, comp141676_c1_seq3,2400,41.0417,0.511812,6,0,,9.00E-31,O34309,"Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)","Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)",GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,,,,,,,,,PPS_BACSU,Bacillus subtilis (strain 168), comp141676_c1_seq4,1267,41.4365,0.50364866,0,0,,1.00E-28,O34796,Uncharacterized phosphotransferase YvkC,Uncharacterized phosphotransferase YvkC,GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,,,,,,,,,YVKC_BACSU,Bacillus subtilis (strain 168), comp141676_c1_seq5,2160,42.4537,0.51065308,0,0,,1.00E-24,Q57962,"Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase) [Cleaved into: Mja pep intein (Mja pepA intein)]","Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase) [Cleaved into: Mja pep intein (Mja pepA intein)]",GO:0005524; GO:0004519; GO:0006094; GO:0016539; GO:0046872; GO:0008986,"ATP binding; endonuclease activity; gluconeogenesis; intein-mediated protein splicing; metal ion binding; pyruvate, water dikinase activity",PF00391;PF02896;PF01326;,,,,,,,,,PPSA_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),gluconeogenesis [GO:0006094]; intein-mediated protein splicing [GO:0016539] comp141676_c1_seq6,1256,40.1274,0.50196505,0,0,,1.00E-32,O34309,"Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)","Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)",GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,7.00E-32,CHOYP_LOC100890479.1.3,,,,,,,PPS_BACSU,Bacillus subtilis (strain 168), comp141676_c1_seq7,2177,42.3978,0.50790987,0,0,,1.00E-27,O34796,Uncharacterized phosphotransferase YvkC,Uncharacterized phosphotransferase YvkC,GO:0005524; GO:0016301,ATP binding; kinase activity,PF00391;PF01326;,,,,,,,,,YVKC_BACSU,Bacillus subtilis (strain 168), comp141676_c1_seq9,563,36.9449,0.31709245,0,0,,5.00E-14,Q0VZ70,Chondramide synthase cmdD [Includes: ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent tyrosine adenylase (TrpA) (Tyrosine activase)],Chondramide synthase cmdD [Includes: ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent tyrosine adenylase (TrpA) (Tyrosine activase)],GO:0043042; GO:0016788; GO:0016874; GO:0016310; GO:0009403; GO:0016772,"amino acid adenylylation by nonribosomal peptide synthase; hydrolase activity, acting on ester bonds; ligase activity; phosphorylation; toxin biosynthetic process; transferase activity, transferring phosphorus-containing groups",PF00501;PF13193;PF00668;PF08241;PF00391;PF00550;PF00975;,,,,,,,,,CHSAD_CHOCO,Chondromyces crocatus,amino acid adenylylation by nonribosomal peptide synthase [GO:0043042]; phosphorylation [GO:0016310]; toxin biosynthetic process [GO:0009403] comp141679_c1_seq4,670,44.0299,0.58600057,40,0,,1.00E-53,Q8R0N9,Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 1) (DHHC-1),Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 1) (DHHC-1),GO:0016021; GO:0016409; GO:0018345; GO:0008270,integral to membrane; palmitoyltransferase activity; protein palmitoylation; zinc ion binding,PF01529;,5.00E-31,CHOYP_LOC100375920.1.1,,,,,,,ZDHC1_MOUSE,Mus musculus (Mouse),protein palmitoylation [GO:0018345] comp141680_c0_seq1,3584,38.3371,0.61144481,0,0,,3.00E-87,Q6C4D4,ATP-dependent RNA helicase DBP2 (EC 3.6.4.13),ATP-dependent RNA helicase DBP2 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0000184; GO:0005634; GO:0006364,"ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; rRNA processing",PF00270;PF00271;,,,,,,,,,DBP2_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]" comp141680_c0_seq2,3160,39.6835,0.57515004,0,0,,0,Q9BUQ8,Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD),Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD),GO:0005524; GO:0004004; GO:0005682; GO:0071013; GO:0000354; GO:0005739; GO:0003676; GO:0005654; GO:0005886,ATP binding; ATP-dependent RNA helicase activity; U5 snRNP; catalytic step 2 spliceosome; cis assembly of pre-catalytic spliceosome; mitochondrion; nucleic acid binding; nucleoplasm; plasma membrane,PF00270;PF00271;,0,CHOYP_DDX23.1.1,,,,,,,DDX23_HUMAN,Homo sapiens (Human),"cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" comp141680_c0_seq3,1067,29.9906,0.79417705,10,9,,5.00E-29,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp141680_c0_seq4,3043,39.4676,0.62115857,0,0,,6.00E-166,Q6C024,Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0008380; GO:0005737; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; cytoplasm; mRNA processing; nucleic acid binding; nucleus,PF00270;PF00271;,,,,,,,,,PRP28_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),"mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing, via transesterification reactions [GO:0000375]" comp141680_c0_seq5,3157,39.7213,0.59062826,0,0,,2.00E-165,Q6C024,Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0008380; GO:0005737; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; cytoplasm; mRNA processing; nucleic acid binding; nucleus,PF00270;PF00271;,,,,,,,,,PRP28_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),"mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing, via transesterification reactions [GO:0000375]" comp141680_c0_seq6,3046,39.4944,0.61968859,0,0,,0,Q4I7F9,Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0008380; GO:0005737; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; cytoplasm; mRNA processing; nucleic acid binding; nucleus,PF00270;PF00271;,0,CHOYP_DDX23.1.1,,,,,,,PRP28_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp141680_c0_seq7,643,30.9487,0.65420719,0,0,,2.00E-23,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp141680_c0_seq8,719,47.1488,0.86373957,135,332,,,,,,,,,,,2.00E-15,ruditapes2_lrc4145,,,,,,, comp141680_c0_seq9,3588,38.4615,0.62195261,56,247,,0,Q9BUQ8,Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD),Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD),GO:0005524; GO:0004004; GO:0005682; GO:0071013; GO:0000354; GO:0005739; GO:0003676; GO:0005654; GO:0005886,ATP binding; ATP-dependent RNA helicase activity; U5 snRNP; catalytic step 2 spliceosome; cis assembly of pre-catalytic spliceosome; mitochondrion; nucleic acid binding; nucleoplasm; plasma membrane,PF00270;PF00271;,,,,,,,,,DDX23_HUMAN,Homo sapiens (Human),"cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" comp141681_c0_seq1,3106,39.6008,0.46214992,15,28,,1.00E-59,O14233,mRNA 3'-end-processing protein rna14,mRNA 3'-end-processing protein rna14,GO:0006379; GO:0005847; GO:0006378; GO:0005739,mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation; mitochondrion,PF05843;,0,CHOYP_CSTF3.1.1,,,,,,,RNA14_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440] comp141681_c0_seq4,3119,39.5319,0.46166268,0,0,,0,Q5RDW9,Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77),Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77),GO:0006397; GO:0005634,mRNA processing; nucleus,PF05843;,0,CHOYP_CSTF3.1.1,,,,,,,CSTF3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397] comp141682_c0_seq1,2565,38.7914,0.36886901,11,46,,6.00E-136,Q15650,Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4),Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4),GO:0005737; GO:0016922; GO:0005815; GO:0005634; GO:0045893; GO:0003713; GO:0006366; GO:0008270,"cytoplasm; ligand-dependent nuclear receptor binding; microtubule organizing center; nucleus; positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter; zinc ion binding",PF04266;PF06221;,,,,,,,,,TRIP4_HUMAN,Homo sapiens (Human),"intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]" comp141682_c0_seq2,2493,38.8688,0.36734629,15,41,,3.00E-136,Q15650,Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4),Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4),GO:0005737; GO:0016922; GO:0005815; GO:0005634; GO:0045893; GO:0003713; GO:0006366; GO:0008270,"cytoplasm; ligand-dependent nuclear receptor binding; microtubule organizing center; nucleus; positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter; zinc ion binding",PF04266;PF06221;,4.00E-64,CHOYP_LOC100367001.1.1,,,,,,,TRIP4_HUMAN,Homo sapiens (Human),"intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]" comp141683_c0_seq1,4165,43.7695,0.61988607,0,0,,9.00E-62,Q13733,Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-4),Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-4),GO:0005524; GO:0006754; GO:0015991; GO:0009566; GO:0046872; GO:0030641; GO:0042391; GO:0005391; GO:0005890; GO:0030317; GO:0007283,ATP binding; ATP biosynthetic process; ATP hydrolysis coupled proton transport; fertilization; metal ion binding; regulation of cellular pH; regulation of membrane potential; sodium:potassium-exchanging ATPase activity; sodium:potassium-exchanging ATPase complex; sperm motility; spermatogenesis,PF00689;PF00690;PF00122;,6.00E-77,CHOYP_AT2B4.1.1,,,,,,,AT1A4_HUMAN,Homo sapiens (Human),ATP hydrolysis coupled proton transport [GO:0015991]; cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; fertilization [GO:0009566]; ion transmembrane transport [GO:0034220]; potassium ion import [GO:0010107]; potassium ion transport [GO:0006813]; regulation of cardiac conduction [GO:1903779]; regulation of cellular pH [GO:0030641]; regulation of membrane potential [GO:0042391]; sodium ion export from cell [GO:0036376]; sodium ion transport [GO:0006814]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp141683_c0_seq10,4183,43.5573,0.63130053,5,0,,0,Q01814,Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),GO:0005524; GO:0030165; GO:0016324; GO:0060088; GO:0007596; GO:0046068; GO:0005509; GO:0030899; GO:0005388; GO:0005516; GO:0021702; GO:0021707; GO:0005929; GO:0090102; GO:0005737; GO:0051480; GO:0050910; GO:0005783; GO:0016021; GO:0007595; GO:0040011; GO:0007626; GO:0046872; GO:0050885; GO:0030182; GO:0043025; GO:0006996; GO:0045299; GO:0005886; GO:0051928; GO:0008361; GO:0048167; GO:0007605; GO:0042428; GO:0050808,ATP binding; PDZ domain binding; apical plasma membrane; auditory receptor cell stereocilium organization; blood coagulation; cGMP metabolic process; calcium ion binding; calcium-dependent ATPase activity; calcium-transporting ATPase activity; calmodulin binding; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; cilium; cochlea development; cytoplasm; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; endoplasmic reticulum; integral to membrane; lactation; locomotion; locomotory behavior; metal ion binding; neuromuscular process controlling balance; neuron differentiation; neuronal cell body; organelle organization; otolith mineralization; plasma membrane; positive regulation of calcium ion transport; regulation of cell size; regulation of synaptic plasticity; sensory perception of sound; serotonin metabolic process; synapse organization,PF12424;PF00689;PF00690;PF00122;PF08282;,0,CHOYP_ATP2B3.1.1,,,,,,,AT2B2_HUMAN,Homo sapiens (Human),auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810] comp141683_c0_seq11,5769,40.7523,0.60564183,0,0,,7.00E-28,Q7XPY2,Plasma membrane ATPase (EC 3.6.3.6) (Proton pump),Plasma membrane ATPase (EC 3.6.3.6) (Proton pump),GO:0005524; GO:0006754; GO:0008553; GO:0016021; GO:0046872; GO:0005886,"ATP binding; ATP biosynthetic process; hydrogen-exporting ATPase activity, phosphorylative mechanism; integral to membrane; metal ion binding; plasma membrane",PF00690;PF00122;,,,,,,,,,PMA1_ORYSJ,Oryza sativa subsp. japonica (Rice),ATP biosynthetic process [GO:0006754]; hydrogen ion transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453] comp141683_c0_seq12,5435,41.196,0.6026782,15,2,,0,Q01814,Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),GO:0005524; GO:0030165; GO:0016324; GO:0060088; GO:0007596; GO:0046068; GO:0005509; GO:0030899; GO:0005388; GO:0005516; GO:0021702; GO:0021707; GO:0005929; GO:0090102; GO:0005737; GO:0051480; GO:0050910; GO:0005783; GO:0016021; GO:0007595; GO:0040011; GO:0007626; GO:0046872; GO:0050885; GO:0030182; GO:0043025; GO:0006996; GO:0045299; GO:0005886; GO:0051928; GO:0008361; GO:0048167; GO:0007605; GO:0042428; GO:0050808,ATP binding; PDZ domain binding; apical plasma membrane; auditory receptor cell stereocilium organization; blood coagulation; cGMP metabolic process; calcium ion binding; calcium-dependent ATPase activity; calcium-transporting ATPase activity; calmodulin binding; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; cilium; cochlea development; cytoplasm; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; endoplasmic reticulum; integral to membrane; lactation; locomotion; locomotory behavior; metal ion binding; neuromuscular process controlling balance; neuron differentiation; neuronal cell body; organelle organization; otolith mineralization; plasma membrane; positive regulation of calcium ion transport; regulation of cell size; regulation of synaptic plasticity; sensory perception of sound; serotonin metabolic process; synapse organization,PF12424;PF00689;PF00690;PF00122;PF08282;,0,CHOYP_ATP2B3.1.1,,,,,,,AT2B2_HUMAN,Homo sapiens (Human),auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810] comp141683_c0_seq13,5785,40.6396,0.59942366,0,0,,5.00E-14,Q9X5X3,Copper-transporting P-type ATPase (EC 3.6.3.4),Copper-transporting P-type ATPase (EC 3.6.3.4),GO:0005524; GO:0005507; GO:0060003; GO:0004008; GO:0016021; GO:0005886,ATP binding; copper ion binding; copper ion export; copper-exporting ATPase activity; integral to membrane; plasma membrane,PF00122;PF00403;,,,,,,,,,ATCU_SINMW,Sinorhizobium medicae (strain WSM419) (Ensifer medicae), comp141683_c0_seq14,5745,40.6963,0.60967675,0,0,,0,Q01814,Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),GO:0005524; GO:0030165; GO:0016324; GO:0060088; GO:0007596; GO:0046068; GO:0005509; GO:0030899; GO:0005388; GO:0005516; GO:0021702; GO:0021707; GO:0005929; GO:0090102; GO:0005737; GO:0051480; GO:0050910; GO:0005783; GO:0016021; GO:0007595; GO:0040011; GO:0007626; GO:0046872; GO:0050885; GO:0030182; GO:0043025; GO:0006996; GO:0045299; GO:0005886; GO:0051928; GO:0008361; GO:0048167; GO:0007605; GO:0042428; GO:0050808,ATP binding; PDZ domain binding; apical plasma membrane; auditory receptor cell stereocilium organization; blood coagulation; cGMP metabolic process; calcium ion binding; calcium-dependent ATPase activity; calcium-transporting ATPase activity; calmodulin binding; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; cilium; cochlea development; cytoplasm; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; endoplasmic reticulum; integral to membrane; lactation; locomotion; locomotory behavior; metal ion binding; neuromuscular process controlling balance; neuron differentiation; neuronal cell body; organelle organization; otolith mineralization; plasma membrane; positive regulation of calcium ion transport; regulation of cell size; regulation of synaptic plasticity; sensory perception of sound; serotonin metabolic process; synapse organization,PF12424;PF00689;PF00690;PF00122;PF08282;,0,CHOYP_ATP2B3.1.1,,,,,,,AT2B2_HUMAN,Homo sapiens (Human),auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810] comp141683_c0_seq2,4141,43.8058,0.62260853,10,15,,0,Q01814,Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),GO:0005524; GO:0030165; GO:0016324; GO:0060088; GO:0007596; GO:0046068; GO:0005509; GO:0030899; GO:0005388; GO:0005516; GO:0021702; GO:0021707; GO:0005929; GO:0090102; GO:0005737; GO:0051480; GO:0050910; GO:0005783; GO:0016021; GO:0007595; GO:0040011; GO:0007626; GO:0046872; GO:0050885; GO:0030182; GO:0043025; GO:0006996; GO:0045299; GO:0005886; GO:0051928; GO:0008361; GO:0048167; GO:0007605; GO:0042428; GO:0050808,ATP binding; PDZ domain binding; apical plasma membrane; auditory receptor cell stereocilium organization; blood coagulation; cGMP metabolic process; calcium ion binding; calcium-dependent ATPase activity; calcium-transporting ATPase activity; calmodulin binding; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; cilium; cochlea development; cytoplasm; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; endoplasmic reticulum; integral to membrane; lactation; locomotion; locomotory behavior; metal ion binding; neuromuscular process controlling balance; neuron differentiation; neuronal cell body; organelle organization; otolith mineralization; plasma membrane; positive regulation of calcium ion transport; regulation of cell size; regulation of synaptic plasticity; sensory perception of sound; serotonin metabolic process; synapse organization,PF12424;PF00689;PF00690;PF00122;PF08282;,6.00E-77,CHOYP_AT2B4.1.1,,,,,,,AT2B2_HUMAN,Homo sapiens (Human),auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810] comp141683_c0_seq3,4595,42.2851,0.62596333,0,0,,8.00E-160,Q65X71,"Probable calcium-transporting ATPase 6, plasma membrane-type (EC 3.6.3.8) (Ca(2+)-ATPase isoform 6)","Probable calcium-transporting ATPase 6, plasma membrane-type (EC 3.6.3.8) (Ca(2+)-ATPase isoform 6)",GO:0005524; GO:0005388; GO:0016021; GO:0046872,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding,PF12515;PF00689;PF00690;PF00122;,,,,,,,,,ACA6_ORYSJ,Oryza sativa subsp. japonica (Rice), comp141683_c0_seq4,5744,40.5815,0.60088438,0,0,,0,Q01814,Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),GO:0005524; GO:0030165; GO:0016324; GO:0060088; GO:0007596; GO:0046068; GO:0005509; GO:0030899; GO:0005388; GO:0005516; GO:0021702; GO:0021707; GO:0005929; GO:0090102; GO:0005737; GO:0051480; GO:0050910; GO:0005783; GO:0016021; GO:0007595; GO:0040011; GO:0007626; GO:0046872; GO:0050885; GO:0030182; GO:0043025; GO:0006996; GO:0045299; GO:0005886; GO:0051928; GO:0008361; GO:0048167; GO:0007605; GO:0042428; GO:0050808,ATP binding; PDZ domain binding; apical plasma membrane; auditory receptor cell stereocilium organization; blood coagulation; cGMP metabolic process; calcium ion binding; calcium-dependent ATPase activity; calcium-transporting ATPase activity; calmodulin binding; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; cilium; cochlea development; cytoplasm; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; endoplasmic reticulum; integral to membrane; lactation; locomotion; locomotory behavior; metal ion binding; neuromuscular process controlling balance; neuron differentiation; neuronal cell body; organelle organization; otolith mineralization; plasma membrane; positive regulation of calcium ion transport; regulation of cell size; regulation of synaptic plasticity; sensory perception of sound; serotonin metabolic process; synapse organization,PF12424;PF00689;PF00690;PF00122;PF08282;,0,CHOYP_ATP2B3.1.1,,,,,,,AT2B2_HUMAN,Homo sapiens (Human),auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810] comp141683_c0_seq5,5769,40.683,0.60377026,0,0,,5.00E-112,P38929,Calcium-transporting ATPase 2 (EC 3.6.3.8) (Vacuolar Ca(2+)-ATPase),Calcium-transporting ATPase 2 (EC 3.6.3.8) (Vacuolar Ca(2+)-ATPase),GO:0005524; GO:0005388; GO:0006874; GO:0000329; GO:0016021; GO:0046872,ATP binding; calcium-transporting ATPase activity; cellular calcium ion homeostasis; fungal-type vacuole membrane; integral to membrane; metal ion binding,PF00689;PF00690;PF00122;,,,,,,,,,ATC2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; transmembrane transport [GO:0055085] comp141683_c0_seq6,5786,40.7535,0.60812487,0,0,,0,Q01814,Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2),GO:0005524; GO:0030165; GO:0016324; GO:0060088; GO:0007596; GO:0046068; GO:0005509; GO:0030899; GO:0005388; GO:0005516; GO:0021702; GO:0021707; GO:0005929; GO:0090102; GO:0005737; GO:0051480; GO:0050910; GO:0005783; GO:0016021; GO:0007595; GO:0040011; GO:0007626; GO:0046872; GO:0050885; GO:0030182; GO:0043025; GO:0006996; GO:0045299; GO:0005886; GO:0051928; GO:0008361; GO:0048167; GO:0007605; GO:0042428; GO:0050808,ATP binding; PDZ domain binding; apical plasma membrane; auditory receptor cell stereocilium organization; blood coagulation; cGMP metabolic process; calcium ion binding; calcium-dependent ATPase activity; calcium-transporting ATPase activity; calmodulin binding; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; cilium; cochlea development; cytoplasm; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; endoplasmic reticulum; integral to membrane; lactation; locomotion; locomotory behavior; metal ion binding; neuromuscular process controlling balance; neuron differentiation; neuronal cell body; organelle organization; otolith mineralization; plasma membrane; positive regulation of calcium ion transport; regulation of cell size; regulation of synaptic plasticity; sensory perception of sound; serotonin metabolic process; synapse organization,PF12424;PF00689;PF00690;PF00122;PF08282;,,,,,,,,,AT2B2_HUMAN,Homo sapiens (Human),auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810] comp141683_c0_seq7,4117,43.7454,0.62254094,0,0,,0,P23634,Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 3.6.3.8) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4),Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 3.6.3.8) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4),GO:0005524; GO:0007596; GO:0005388; GO:0005887; GO:0046872; GO:1902083; GO:0043234; GO:1902305; GO:0097110,ATP binding; blood coagulation; calcium-transporting ATPase activity; integral to plasma membrane; metal ion binding; negative regulation of peptidyl-cysteine S-nitrosylation; protein complex; regulation of sodium ion transmembrane transport; scaffold protein binding,PF12424;PF00689;PF00690;PF00122;,0,CHOYP_ATP2B3.1.1,,,,,,,AT2B4_HUMAN,Homo sapiens (Human),calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to epinephrine stimulus [GO:0071872]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; negative regulation of adrenergic receptor signaling pathway involved in heart process [GO:1901205]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp141683_c0_seq8,4141,43.6851,0.62057125,0,0,,3.00E-14,Q9X5X3,Copper-transporting P-type ATPase (EC 3.6.3.4),Copper-transporting P-type ATPase (EC 3.6.3.4),GO:0005524; GO:0005507; GO:0060003; GO:0004008; GO:0016021; GO:0005886,ATP binding; copper ion binding; copper ion export; copper-exporting ATPase activity; integral to membrane; plasma membrane,PF00122;PF00403;,0,CHOYP_ATP2B3.1.1,,,,,,,ATCU_SINMW,Sinorhizobium medicae (strain WSM419) (Ensifer medicae), comp141689_c0_seq1,2779,46.0237,0.46979017,52,18,,0,Q8BFY9,Transportin-1 (Importin beta-2) (Karyopherin beta-2),Transportin-1 (Importin beta-2) (Karyopherin beta-2),GO:0005737; GO:0006886; GO:0005634,cytoplasm; intracellular protein transport; nucleus,PF03810;,0,CHOYP_TNPO1.1.1,,,,,,,TNPO1_MOUSE,Mus musculus (Mouse),"NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]" comp141689_c0_seq2,2169,46.0581,0.4705307,15,9,,9.00E-15,P52296,Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97),Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97),GO:0005737; GO:0006886; GO:0005635; GO:0006913; GO:0008565,cytoplasm; intracellular protein transport; nuclear envelope; nucleocytoplasmic transport; protein transporter activity,PF03810;,,,,,,,,,IMB1_RAT,Rattus norvegicus (Rat),"NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]" comp141690_c1_seq1,1477,38.1855,0.42800684,106,273,,7.00E-54,Q174D3,Mediator of RNA polymerase II transcription subunit 19 (Mediator complex subunit 19),Mediator of RNA polymerase II transcription subunit 19 (Mediator complex subunit 19),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF10278;,4.00E-55,CHOYP_RS9.12.13,,,,,,,MED19_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"transcription, DNA-templated [GO:0006351]" comp141691_c0_seq1,932,43.2403,0.42538043,87,89,,5.00E-74,Q23424,Transmembrane GTPase fzo-1 (EC 3.6.5.-),Transmembrane GTPase fzo-1 (EC 3.6.5.-),GO:0005525; GO:0003924; GO:0016021; GO:0008053; GO:0005741,GTP binding; GTPase activity; integral to membrane; mitochondrial fusion; mitochondrial outer membrane,PF00350;PF04799;,3.00E-80,CHOYP_PHUM_PHUM579670.1.1,,,,,,,FZO1_CAEEL,Caenorhabditis elegans,mitochondrial fusion [GO:0008053] comp141691_c1_seq1,2310,38.7446,0.48910062,5,11,,1.00E-131,Q8R500,Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2),Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2),GO:0005525; GO:0003924; GO:0005829; GO:0016021; GO:0031306; GO:0008053; GO:0007006; GO:0048662; GO:0006626,GTP binding; GTPase activity; cytosol; integral to membrane; intrinsic to mitochondrial outer membrane; mitochondrial fusion; mitochondrial membrane organization; negative regulation of smooth muscle cell proliferation; protein targeting to mitochondrion,PF00350;PF04799;,2.00E-16,CHOYP_MFN2.1.1,,,,,,,MFN2_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; autophagy [GO:0006914]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; negative regulation of cell proliferation [GO:0008285]; negative regulation of smooth muscle cell proliferation [GO:0048662]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986] comp141691_c1_seq2,1694,42.0307,0.51054235,0,0,,,,,,,,,2.00E-16,CHOYP_MFN2.1.1,,,,,,,,, comp141691_c1_seq3,1715,41.9242,0.50690316,0,0,,,,,,,,,2.00E-16,CHOYP_PHUM_PHUM579670.1.1,,,,,,,,, comp141691_c1_seq5,2331,38.7387,0.48496741,0,0,,1.00E-129,Q8R500,Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2),Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2),GO:0005525; GO:0003924; GO:0005829; GO:0016021; GO:0031306; GO:0008053; GO:0007006; GO:0048662; GO:0006626,GTP binding; GTPase activity; cytosol; integral to membrane; intrinsic to mitochondrial outer membrane; mitochondrial fusion; mitochondrial membrane organization; negative regulation of smooth muscle cell proliferation; protein targeting to mitochondrion,PF00350;PF04799;,,,,,,,,,MFN2_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; autophagy [GO:0006914]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; negative regulation of cell proliferation [GO:0008285]; negative regulation of smooth muscle cell proliferation [GO:0048662]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986] comp141692_c1_seq1,971,42.9454,0.49670219,0,0,,3.00E-79,Q12933,TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3),TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3),GO:0005174; GO:0035631; GO:0007250; GO:0006919; GO:0097190; GO:0043623; GO:0005829; GO:0045087; GO:0009898; GO:0043507; GO:0051092; GO:0050870; GO:0002726; GO:2001238; GO:0032743; GO:0090073; GO:0070534; GO:0051865; GO:0030163; GO:0070207; GO:2001239; GO:0051023; GO:0004871; GO:0046625; GO:0033209; GO:0004842; GO:0008270,CD40 receptor binding; CD40 receptor complex; activation of NF-kappaB-inducing kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; cellular protein complex assembly; cytosol; innate immune response; internal side of plasma membrane; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; positive regulation of T cell cytokine production; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-2 production; positive regulation of protein homodimerization activity; protein K63-linked ubiquitination; protein autoubiquitination; protein catabolic process; protein homotrimerization; regulation of extrinsic apoptotic signaling pathway in absence of ligand; regulation of immunoglobulin secretion; signal transducer activity; sphingolipid binding; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF16673;PF00097;PF02176;,,,,,,,,,TRAF2_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein complex assembly [GO:0006461]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of necrotic cell death [GO:0010939]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp141692_c1_seq2,1289,43.2118,0.40178596,4,29,,4.00E-90,P39429,TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2),TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2),GO:0035631; GO:0007250; GO:0006915; GO:0043623; GO:0005737; GO:0009898; GO:0043066; GO:0043507; GO:0051092; GO:0002726; GO:2001238; GO:0032743; GO:0090073; GO:0070534; GO:0051865; GO:0030163; GO:0070207; GO:0051023; GO:0046625; GO:0033209; GO:0004842; GO:0008270,CD40 receptor complex; activation of NF-kappaB-inducing kinase activity; apoptotic process; cellular protein complex assembly; cytoplasm; internal side of plasma membrane; negative regulation of apoptotic process; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell cytokine production; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-2 production; positive regulation of protein homodimerization activity; protein K63-linked ubiquitination; protein autoubiquitination; protein catabolic process; protein homotrimerization; regulation of immunoglobulin secretion; sphingolipid binding; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF16673;PF00097;PF02176;,3.00E-17,CHOYP_LOC101161601.1.1,,,,,,,TRAF2_MOUSE,Mus musculus (Mouse),activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp141692_c1_seq3,505,42.5743,0.39786981,43,134,,1.00E-16,Q6DJN2,TNF receptor-associated factor 6-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),TNF receptor-associated factor 6-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),GO:0050852; GO:0007250; GO:0046849; GO:0048468; GO:0005737; GO:0070498; GO:0009887; GO:0001503; GO:0043123; GO:0043507; GO:0031666; GO:0045672; GO:0070534; GO:0051865; GO:0042981; GO:0004871; GO:0004842; GO:0008270,T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; bone remodeling; cell development; cytoplasm; interleukin-1-mediated signaling pathway; organ morphogenesis; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of osteoclast differentiation; protein K63-linked ubiquitination; protein autoubiquitination; regulation of apoptotic process; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,TRF6B_XENLA,Xenopus laevis (African clawed frog),activation of NF-kappaB-inducing kinase activity [GO:0007250]; immune response [GO:0006955]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981] comp141692_c1_seq4,962,42.9314,0.47808562,0,0,,3.00E-79,Q12933,TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3),TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3),GO:0005174; GO:0035631; GO:0007250; GO:0006919; GO:0097190; GO:0043623; GO:0005829; GO:0045087; GO:0009898; GO:0043507; GO:0051092; GO:0050870; GO:0002726; GO:2001238; GO:0032743; GO:0090073; GO:0070534; GO:0051865; GO:0030163; GO:0070207; GO:2001239; GO:0051023; GO:0004871; GO:0046625; GO:0033209; GO:0004842; GO:0008270,CD40 receptor binding; CD40 receptor complex; activation of NF-kappaB-inducing kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; cellular protein complex assembly; cytosol; innate immune response; internal side of plasma membrane; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; positive regulation of T cell cytokine production; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-2 production; positive regulation of protein homodimerization activity; protein K63-linked ubiquitination; protein autoubiquitination; protein catabolic process; protein homotrimerization; regulation of extrinsic apoptotic signaling pathway in absence of ligand; regulation of immunoglobulin secretion; signal transducer activity; sphingolipid binding; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF16673;PF00097;PF02176;,,,,,,,,,TRAF2_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein complex assembly [GO:0006461]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of necrotic cell death [GO:0010939]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp141692_c1_seq5,585,43.5897,0.46920561,0,0,,3.00E-27,Q9BUZ4,TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83),TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83),GO:0003677; GO:0006915; GO:0005737; GO:0005856; GO:0005634; GO:0048471; GO:0005886; GO:0046330; GO:0090073; GO:0045860; GO:0042981; GO:0007585; GO:0030323; GO:0007165; GO:0005923; GO:0004842; GO:0008270,DNA binding; apoptotic process; cytoplasm; cytoskeleton; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of JNK cascade; positive regulation of protein homodimerization activity; positive regulation of protein kinase activity; regulation of apoptotic process; respiratory gaseous exchange; respiratory tube development; signal transduction; tight junction; ubiquitin-protein ligase activity; zinc ion binding,PF00097;PF02176;,,,,,,,,,TRAF4_HUMAN,Homo sapiens (Human),activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; respiratory gaseous exchange [GO:0007585]; respiratory tube development [GO:0030323]; signal transduction [GO:0007165] comp141692_c1_seq6,594,43.6027,0.49796889,0,0,,,,,,,,,2.00E-22,CHOYP_BRAFLDRAFT_237984.1.1,,,,,,,,, comp141692_c1_seq7,380,47.1053,0.5245343,16,19,,9.00E-06,P11467,RING finger protein DG17 (Probable TNF receptor-associated factor DDB_G0290961),RING finger protein DG17 (Probable TNF receptor-associated factor DDB_G0290961),GO:0005737; GO:0007275; GO:0008270,cytoplasm; multicellular organismal development; zinc ion binding,PF00917;PF02176;,,,,,,,,,DG17_DICDI,Dictyostelium discoideum (Slime mold),multicellular organism development [GO:0007275] comp141692_c1_seq8,1298,43.2203,0.41591982,0,0,,4.00E-90,P39429,TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2),TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2),GO:0035631; GO:0007250; GO:0006915; GO:0043623; GO:0005737; GO:0009898; GO:0043066; GO:0043507; GO:0051092; GO:0002726; GO:2001238; GO:0032743; GO:0090073; GO:0070534; GO:0051865; GO:0030163; GO:0070207; GO:0051023; GO:0046625; GO:0033209; GO:0004842; GO:0008270,CD40 receptor complex; activation of NF-kappaB-inducing kinase activity; apoptotic process; cellular protein complex assembly; cytoplasm; internal side of plasma membrane; negative regulation of apoptotic process; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell cytokine production; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of interleukin-2 production; positive regulation of protein homodimerization activity; protein K63-linked ubiquitination; protein autoubiquitination; protein catabolic process; protein homotrimerization; regulation of immunoglobulin secretion; sphingolipid binding; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF16673;PF00097;PF02176;,,,,,,,,,TRAF2_MOUSE,Mus musculus (Mouse),activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp141693_c0_seq1,2164,38.2163,0.49542345,196,174,,6.00E-09,Q43468,Heat shock protein STI (GmSTI) (Stress-inducible protein),Hsp70-Hsp90 organizing protein 1 (GmHop-1) (Heat shock protein STI) (GmSTI) (Stress-inducible protein),GO:0009408; GO:0006986,response to heat; response to unfolded protein,PF00515;PF13414;PF13181;,,,,,,,,,STIP_SOYBN,Glycine max (Soybean) (Glycine hispida),cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; chaperone-mediated protein complex assembly [GO:0051131]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; response to wounding [GO:0009611] comp141694_c0_seq1,3574,37.0733,0.2695241,122,280,,2.00E-22,Q9H7N4,"Splicing factor, arginine/serine-rich 19 (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)","Splicing factor, arginine/serine-rich 19 (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)",GO:0003723; GO:0008380; GO:0006397; GO:0005634; GO:0006366,RNA binding; RNA splicing; mRNA processing; nucleus; transcription from RNA polymerase II promoter,,4.00E-34,CHOYP_LOC100476601.1.1,,,,,,,SFR19_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp141694_c0_seq7,2222,33.6184,0.27795272,3,0,,2.00E-12,Q9H7N4,"Splicing factor, arginine/serine-rich 19 (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)","Splicing factor, arginine/serine-rich 19 (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)",GO:0003723; GO:0008380; GO:0006397; GO:0005634; GO:0006366,RNA binding; RNA splicing; mRNA processing; nucleus; transcription from RNA polymerase II promoter,,,,,,,,,,SFR19_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp141695_c0_seq1,3122,45.4837,0.55446244,17,4,,3.00E-173,Q5H8C4,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),GO:0031045; GO:0007626; GO:0007399; GO:0015031; GO:0035176,dense core granule; locomotory behavior; nervous system development; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp141695_c0_seq10,2231,45.4056,0.5908029,0,0,,1.00E-140,Q5H8C4,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),GO:0031045; GO:0007626; GO:0007399; GO:0015031; GO:0035176,dense core granule; locomotory behavior; nervous system development; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp141695_c0_seq2,3167,45.4373,0.55998048,0,0,,6.00E-171,Q5H8C4,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein),GO:0031045; GO:0007626; GO:0007399; GO:0015031; GO:0035176,dense core granule; locomotory behavior; nervous system development; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,0,CHOYP_BRAFLDRAFT_226506.1.3,,,,,,,VP13A_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp141695_c0_seq6,2249,45.976,0.57409816,0,0,,2.00E-34,Q54LB8,Putative vacuolar protein sorting-associated protein 13A,Putative vacuolar protein sorting-associated protein 13A,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,1.00E-89,CHOYP_BRAFLDRAFT_226506.1.3,,,,,,,VP13A_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp141695_c0_seq8,2125,46.1176,0.58538186,0,0,,1.00E-93,Q96RL7,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),GO:0006895; GO:0008219; GO:0031045; GO:0005622; GO:0007626; GO:0007399; GO:0008104; GO:0015031; GO:0035176,Golgi to endosome transport; cell death; dense core granule; intracellular; locomotory behavior; nervous system development; protein localization; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,2.00E-74,CHOYP_BRAFLDRAFT_226506.3.3,,,,,,,VP13A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp141695_c0_seq9,2080,46.3462,0.58313193,0,0,,7.00E-25,Q54LB8,Putative vacuolar protein sorting-associated protein 13A,Putative vacuolar protein sorting-associated protein 13A,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp141697_c0_seq1,2071,38.7735,0.33456721,0,0,,7.00E-44,Q9BTF0,THUMP domain-containing protein 2,THUMP domain-containing protein 2,GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF02926;PF01170;,,,,,,,,,THUM2_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp141697_c0_seq11,735,42.7211,0.2090913,0,0,,5.00E-12,O29011,tRNA (guanine(10)-N2)-dimethyltransferase (EC 2.1.1.213) (tRNA:G10 dimethyltransferase),tRNA (guanine(10)-N2)-dimethyltransferase (EC 2.1.1.213) (tRNA:G10 dimethyltransferase),GO:0005737; GO:0008168; GO:0000049; GO:0008033,cytoplasm; methyltransferase activity; tRNA binding; tRNA processing,PF02926;PF01170;,,,,,,,,,TMG10_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126), comp141697_c0_seq2,1506,38.7118,0.28428611,0,0,,2.00E-44,Q9BTF0,THUMP domain-containing protein 2,THUMP domain-containing protein 2,GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF02926;PF01170;,,,,,,,,,THUM2_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp141697_c0_seq6,1549,38.4764,0.29737734,0,14,,1.00E-43,Q9CZB3,THUMP domain-containing protein 2,THUMP domain-containing protein 2,GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF02926;PF01170;,,,,,,,,,THUM2_MOUSE,Mus musculus (Mouse),tRNA methylation [GO:0030488] comp141697_c0_seq8,897,41.9175,0.35579498,0,2,,8.00E-45,Q9BTF0,THUMP domain-containing protein 2,THUMP domain-containing protein 2,GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF02926;PF01170;,,,,,,,,,THUM2_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp141697_c0_seq9,677,42.2452,0.19909014,0,0,,3.00E-10,C5D3E5,Demethylmenaquinone methyltransferase (EC 2.1.1.163) (Menaquinone biosynthesis C-methyltransferase UbiE),Demethylmenaquinone methyltransferase (EC 2.1.1.163),GO:0009234; GO:0008168,menaquinone biosynthetic process; methyltransferase activity,PF01209;,,,,,,,,,UBIE_GEOSW,Geobacillus sp. (strain WCH70),menaquinone biosynthetic process [GO:0009234] comp141698_c0_seq1,2790,30.6093,0.44520908,99,205,,4.00E-85,P61291,Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma),Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma),GO:0097371; GO:0006915; GO:0007049; GO:0005737; GO:0061133; GO:2001237; GO:0005634; GO:0002039; GO:0008537; GO:0061136,MDM2/MDM4 family protein binding; apoptotic process; cell cycle; cytoplasm; endopeptidase activator activity; negative regulation of extrinsic apoptotic signaling pathway; nucleus; p53 binding; proteasome activator complex; regulation of proteasomal protein catabolic process,PF02251;PF02252;,,,,,,,,,PSME3_PIG,Sus scrofa (Pig),apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of endopeptidase activity [GO:0010950]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of proteasomal protein catabolic process [GO:0061136] comp141698_c0_seq2,2769,30.5164,0.45097297,16,69,,3.00E-84,Q5F3J5,Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma),Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma),GO:0008537,proteasome activator complex,PF02251;PF02252;,5.00E-57,CHOYP_LOC410403.1.1,,,,,,,PSME3_CHICK,Gallus gallus (Chicken),negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of endopeptidase activity [GO:0010950]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of proteasomal protein catabolic process [GO:0061136] comp141699_c1_seq1,2706,38.3222,0.52405488,503,1417,,0,Q5RDE7,"Cysteine desulfurase, mitochondrial (EC 2.8.1.7)","Cysteine desulfurase, mitochondrial (EC 2.8.1.7)",GO:0006777; GO:0031071; GO:0006534; GO:0005739; GO:0005634; GO:0030170,Mo-molybdopterin cofactor biosynthetic process; cysteine desulfurase activity; cysteine metabolic process; mitochondrion; nucleus; pyridoxal phosphate binding,PF00266;,0,CHOYP_NFS1.1.1,,,,,,,NFS1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),[2Fe-2S] cluster assembly [GO:0044571]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp141701_c0_seq1,1116,44.4444,0.66559683,0,0,,3.00E-24,Q15652,Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8),Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8),GO:0007596; GO:0016568; GO:0051213; GO:0046872; GO:0005654; GO:0006355; GO:0046966; GO:0006351,"blood coagulation; chromatin modification; dioxygenase activity; metal ion binding; nucleoplasm; regulation of transcription, DNA-dependent; thyroid hormone receptor binding; transcription, DNA-dependent",PF02373;,8.00E-50,CHOYP_LOC100378099.1.1,,,,,,,JHD2C_HUMAN,Homo sapiens (Human),"blood coagulation [GO:0007596]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141701_c0_seq3,2285,41.0066,0.6027311,0,0,,3.00E-16,Q6PCM1,Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A),Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A),GO:0030521; GO:0001047; GO:0005737; GO:0051213; GO:0046293; GO:0033169; GO:0036123; GO:0009755; GO:0005506; GO:0051573; GO:0005634; GO:0045944; GO:0003700; GO:0007290; GO:0000976; GO:0006351,"androgen receptor signaling pathway; core promoter binding; cytoplasm; dioxygenase activity; formaldehyde biosynthetic process; histone H3-K9 demethylation; histone H3-K9 dimethylation; hormone-mediated signaling pathway; iron ion binding; negative regulation of histone H3-K9 methylation; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; spermatid nucleus elongation; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF02373;,,,,,,,,,KDM3A_MOUSE,Mus musculus (Mouse),"androgen receptor signaling pathway [GO:0030521]; formaldehyde biosynthetic process [GO:0046293]; histone H3-K9 demethylation [GO:0033169]; histone H3-K9 dimethylation [GO:0036123]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584]; negative regulation of histone H3-K9 methylation [GO:0051573]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell population maintenance [GO:2000036]; response to hypoxia [GO:0001666]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp141702_c0_seq1,2288,45.0175,0.56102952,10,440,,9.00E-13,Q6NZQ8,E3 ubiquitin-protein ligase MARCH1 (EC 6.3.2.-) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I),E3 ubiquitin-protein ligase MARCH1 (EC 6.3.2.-) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I),GO:0005794; GO:0042287; GO:0002495; GO:0030659; GO:0031901; GO:0005789; GO:0006955; GO:0016021; GO:0031902; GO:0005765; GO:0005886; GO:0000209; GO:0032588; GO:0004842; GO:0008270,Golgi apparatus; MHC protein binding; antigen processing and presentation of peptide antigen via MHC class II; cytoplasmic vesicle membrane; early endosome membrane; endoplasmic reticulum membrane; immune response; integral to membrane; late endosome membrane; lysosomal membrane; plasma membrane; protein polyubiquitination; trans-Golgi network membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,MARH1_MOUSE,Mus musculus (Mouse),antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; immune response [GO:0006955]; protein polyubiquitination [GO:0000209] comp141702_c0_seq2,1963,47.3765,0.56346959,0,6,,8.00E-21,Q32L65,E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II),GO:0031410; GO:0006897; GO:0005783; GO:0005789; GO:0010008; GO:0016021; GO:0005765; GO:0004842; GO:0008270,cytoplasmic vesicle; endocytosis; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; integral to membrane; lysosomal membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,MARH2_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; protein ubiquitination [GO:0016567] comp141703_c0_seq1,2135,31.1944,0.67864939,16,77,,2.00E-82,P35604,Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP),Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP),GO:0030126; GO:0006891; GO:0006886; GO:0006890,"COPI vesicle coat; intra-Golgi vesicle-mediated transport; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER",PF01217;,1.00E-89,CHOYP_LOC100115298.1.1,,,,,,,COPZ1_BOVIN,Bos taurus (Bovine),"intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; toxin transport [GO:1901998]" comp141703_c0_seq2,1454,33.2187,0.57881929,9,334,,1.00E-84,P35604,Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP),Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP),GO:0030126; GO:0006891; GO:0006886; GO:0006890,"COPI vesicle coat; intra-Golgi vesicle-mediated transport; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER",PF01217;,7.00E-90,CHOYP_LOC100115298.1.1,5.00E-127,ruditapes2_c2075,,,,,COPZ1_BOVIN,Bos taurus (Bovine),"intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; toxin transport [GO:1901998]" comp141703_c0_seq4,1474,33.175,0.59769056,0,0,,1.00E-30,P53600,Coatomer subunit zeta (Zeta-coat protein) (Zeta-COP),Coatomer subunit zeta (Zeta-coat protein) (Zeta-COP),GO:0030126; GO:0015031; GO:0006890,"COPI vesicle coat; protein transport; retrograde vesicle-mediated transport, Golgi to ER",PF01217;,,,,,,,,,COPZ_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp141707_c0_seq1,2362,32.8959,0.56830217,671,87,,1.00E-80,Q9H0I3,Coiled-coil domain-containing protein 113,Coiled-coil domain-containing protein 113,GO:0005737; GO:0005634; GO:0043234,cytoplasm; nucleus; protein complex,PF13870;,7.00E-143,CHOYP_LOC100374446.1.1,,,,,,,CC113_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384] comp141707_c0_seq3,1029,31.001,0.43740486,17,0,,,,,,,,,,,4.00E-13,ruditapes_c10528,,,,,,, comp141708_c0_seq1,3664,34.6343,0.3952193,36,45,,1.00E-07,Q29RK0,Zinc finger protein 574,Zinc finger protein 574,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN574_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141708_c0_seq2,1468,36.2398,0.4280305,6,43,,4.00E-13,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp141708_c0_seq3,3691,34.5435,0.39449866,20,83,,9.00E-06,Q61967,Zinc finger protein 90 (Zfp-90) (Zinc finger protein NK10),Zinc finger protein 90 (Zfp-90) (Zinc finger protein NK10),GO:0003677; GO:0001078; GO:0046872; GO:0043392; GO:0005634; GO:0045893,"DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; metal ion binding; negative regulation of DNA binding; nucleus; positive regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP90_MOUSE,Mus musculus (Mouse),"negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp141708_c0_seq5,809,39.4314,0.36742324,0,0,,2.00E-07,P57071,PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298),PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD15_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141709_c0_seq1,684,45.614,0.41137699,12,98,,6.00E-102,Q9BV94,ER degradation-enhancing alpha-mannosidase-like protein 2,ER degradation-enhancing alpha-mannosidase-like protein 2,GO:0005509; GO:0005788; GO:0005789; GO:0005576; GO:0043687; GO:0018279; GO:0006457; GO:0006986,calcium ion binding; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular region; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding; response to unfolded protein,PF01532;,4.00E-83,CHOYP_AAEL_AAEL005639.1.1,,,,,,,EDEM2_HUMAN,Homo sapiens (Human),"endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on B branch [GO:0036509]" comp141709_c1_seq1,411,42.3358,0.39115924,13,38,,6.00E-21,Q9C512,"Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1 (AtMANIb) (EC 3.2.1.113) (Alpha-mannosidase IB)","Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1 (AtMANIb) (EC 3.2.1.113) (Alpha-mannosidase IB)",GO:0005794; GO:0000139; GO:0006491; GO:0004559; GO:0005509; GO:0005768; GO:0016021; GO:0004571; GO:0048364; GO:0005802,"Golgi apparatus; Golgi membrane; N-glycan processing; alpha-mannosidase activity; calcium ion binding; endosome; integral to membrane; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; root development; trans-Golgi network",PF01532;,,,,,,,,,MNS1_ARATH,Arabidopsis thaliana (Mouse-ear cress),N-glycan processing [GO:0006491] comp141710_c0_seq1,2991,42.2935,0.44257475,3,17,,0,Q6IQ26,DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1),DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1),GO:0005794; GO:0017112; GO:0016020,Golgi apparatus; Rab guanyl-nucleotide exchange factor activity; membrane,PF03455;PF02141;PF01477;PF02759;PF03456;,,,,,,,,,DEN5A_HUMAN,Homo sapiens (Human),"detection of mechanical stimulus [GO:0050982]; retrograde transport, endosome to Golgi [GO:0042147]" comp141710_c0_seq2,4698,41.3793,0.50084044,7,3,,0,A2RSQ0,DENN domain-containing protein 5B (Rab6IP1-like protein),DENN domain-containing protein 5B (Rab6IP1-like protein),GO:0017112; GO:0016021; GO:0016020,Rab guanyl-nucleotide exchange factor activity; integral to membrane; membrane,PF03455;PF02141;PF01477;PF02759;PF03456;,2.00E-110,CHOYP_DEN5A.1.1,,,,,,,DEN5B_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141710_c0_seq3,2976,42.3723,0.44332132,2,0,,2.00E-26,Q3U1Y4,DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4),DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4),GO:0005794; GO:0017112,Golgi apparatus; Rab guanyl-nucleotide exchange factor activity,PF03455;PF02141;PF03456;,,,,,,,,,DEN4B_MOUSE,Mus musculus (Mouse),regulation of Rab protein signal transduction [GO:0032483] comp141710_c0_seq4,4635,41.3592,0.49278077,2,0,,0,A2RSQ0,DENN domain-containing protein 5B (Rab6IP1-like protein),DENN domain-containing protein 5B (Rab6IP1-like protein),GO:0017112; GO:0016021; GO:0016020,Rab guanyl-nucleotide exchange factor activity; integral to membrane; membrane,PF03455;PF02141;PF01477;PF02759;PF03456;,2.00E-110,CHOYP_DEN5A.1.1,,,,,,,DEN5B_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp141710_c0_seq5,1701,41.9753,0.46749451,0,6,,3.00E-22,Q3U1Y4,DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4),DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4),GO:0005794; GO:0017112,Golgi apparatus; Rab guanyl-nucleotide exchange factor activity,PF03455;PF02141;PF03456;,2.00E-34,CHOYP_DEN5B.1.1,,,,,,,DEN4B_MOUSE,Mus musculus (Mouse),regulation of Rab protein signal transduction [GO:0032483] comp141710_c0_seq6,4656,41.3875,0.50012694,13,0,,4.00E-22,Q6ZPE2,Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1),Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1),GO:0005085; GO:0005634; GO:0016791; GO:0005543; GO:0001691; GO:0001558; GO:0007283,guanyl-nucleotide exchange factor activity; nucleus; phosphatase activity; phospholipid binding; pseudophosphatase activity; regulation of cell growth; spermatogenesis,PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;,2.00E-110,CHOYP_DEN5A.1.1,,,,,,,MTMR5_MOUSE,Mus musculus (Mouse),regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283] comp141712_c0_seq1,1509,39.9602,1.05090521,35,165,,3.00E-19,Q92843,Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W),Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W),GO:0060011; GO:0006915; GO:0005829; GO:0031966; GO:0043066; GO:0007283,Sertoli cell proliferation; apoptotic process; cytosol; mitochondrial membrane; negative regulation of apoptotic process; spermatogenesis,PF00452;PF02180;,,,,,,,,,B2CL2_HUMAN,Homo sapiens (Human),extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; Sertoli cell proliferation [GO:0060011]; spermatogenesis [GO:0007283] comp141712_c0_seq2,1760,38.9205,1.00786768,81,132,,,,,,,,,,,4.00E-35,ruditapes2_c1129,,,,,,, comp141712_c0_seq3,1778,38.9764,0.99559838,116,234,,2.00E-13,Q00709,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,GO:0001782; GO:0002326; GO:0042100; GO:0050853; GO:0043375; GO:0000082; GO:0033077; GO:0043029; GO:0007015; GO:0031103; GO:0007409; GO:0001662; GO:0001658; GO:0007569; GO:0016049; GO:0016337; GO:0071310; GO:0015267; GO:0016248; GO:0021747; GO:0005829; GO:0051607; GO:0048589; GO:0048546; GO:0043583; GO:0032469; GO:0005789; GO:0008625; GO:0048041; GO:0022612; GO:0032835; GO:0031069; GO:0048873; GO:0070059; GO:0002320; GO:0008584; GO:0006582; GO:0030318; GO:0014031; GO:0001656; GO:0005741; GO:0043209; GO:2000811; GO:0043066; GO:0010523; GO:0030308; GO:0030336; GO:0032848; GO:2001243; GO:0045930; GO:0033033; GO:0043524; GO:0030279; GO:0033689; GO:0046671; GO:0051402; GO:0031965; GO:0048599; GO:0035265; GO:0001503; GO:0001541; GO:0018105; GO:0018107; GO:0048753; GO:0046930; GO:0030890; GO:0043085; GO:0030307; GO:0045636; GO:0040018; GO:0014042; GO:0033138; GO:0048743; GO:0014911; GO:0009791; GO:0006470; GO:0000209; GO:0072593; GO:0001952; GO:0010559; GO:0046902; GO:0051881; GO:0006808; GO:0043497; GO:0043496; GO:0032880; GO:0031647; GO:0022898; GO:0045069; GO:0001836; GO:0003014; GO:0006974; GO:0010224; GO:0001101; GO:0034097; GO:0042493; GO:0009605; GO:0010332; GO:0051384; GO:0042542; GO:0010039; GO:0035094; GO:0009636; GO:0043565; GO:0048536; GO:0048538,"B cell homeostasis; B cell lineage commitment; B cell proliferation; B cell receptor signaling pathway; CD8-positive, alpha-beta T cell lineage commitment; G1/S transition of mitotic cell cycle; T cell differentiation in thymus; T cell homeostasis; actin filament organization; axon regeneration; axonogenesis; behavioral fear response; branching involved in ureteric bud morphogenesis; cell aging; cell growth; cell-cell adhesion; cellular response to organic substance; channel activity; channel inhibitor activity; cochlear nucleus development; cytosol; defense response to virus; developmental growth; digestive tract morphogenesis; ear development; endoplasmic reticulum calcium ion homeostasis; endoplasmic reticulum membrane; extrinsic apoptotic signaling pathway via death domain receptors; focal adhesion assembly; gland morphogenesis; glomerulus development; hair follicle morphogenesis; homeostasis of number of cells within a tissue; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; lymphoid progenitor cell differentiation; male gonad development; melanin metabolic process; melanocyte differentiation; mesenchymal cell development; metanephros development; mitochondrial outer membrane; myelin sheath; negative regulation of anoikis; negative regulation of apoptotic process; negative regulation of calcium ion transport into cytosol; negative regulation of cell growth; negative regulation of cell migration; negative regulation of cellular pH reduction; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of mitotic cell cycle; negative regulation of myeloid cell apoptotic process; negative regulation of neuron apoptotic process; negative regulation of ossification; negative regulation of osteoblast proliferation; negative regulation of retinal cell programmed cell death; neuron apoptotic process; nuclear membrane; oocyte development; organ growth; ossification; ovarian follicle development; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; pigment granule organization; pore complex; positive regulation of B cell proliferation; positive regulation of catalytic activity; positive regulation of cell growth; positive regulation of melanocyte differentiation; positive regulation of multicellular organism growth; positive regulation of neuron maturation; positive regulation of peptidyl-serine phosphorylation; positive regulation of skeletal muscle fiber development; positive regulation of smooth muscle cell migration; post-embryonic development; protein dephosphorylation; protein polyubiquitination; reactive oxygen species metabolic process; regulation of cell-matrix adhesion; regulation of glycoprotein biosynthetic process; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; regulation of nitrogen utilization; regulation of protein heterodimerization activity; regulation of protein homodimerization activity; regulation of protein localization; regulation of protein stability; regulation of transmembrane transporter activity; regulation of viral genome replication; release of cytochrome c from mitochondria; renal system process; response to DNA damage stimulus; response to UV-B; response to acid; response to cytokine stimulus; response to drug; response to external stimulus; response to gamma radiation; response to glucocorticoid stimulus; response to hydrogen peroxide; response to iron ion; response to nicotine; response to toxic substance; sequence-specific DNA binding; spleen development; thymus development",PF00452;PF02180;,,,3.00E-37,ruditapes_c3202,,,,,BCL2_CHICK,Gallus gallus (Chicken),"actin filament organization [GO:0007015]; axonogenesis [GO:0007409]; axon regeneration [GO:0031103]; B cell homeostasis [GO:0001782]; B cell lineage commitment [GO:0002326]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; behavioral fear response [GO:0001662]; branching involved in ureteric bud morphogenesis [GO:0001658]; CD8-positive, alpha-beta T cell lineage commitment [GO:0043375]; cell aging [GO:0007569]; cell growth [GO:0016049]; cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to organic substance [GO:0071310]; cochlear nucleus development [GO:0021747]; defense response to virus [GO:0051607]; digestive tract morphogenesis [GO:0048546]; ear development [GO:0043583]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; focal adhesion assembly [GO:0048041]; gland morphogenesis [GO:0022612]; glomerulus development [GO:0032835]; homeostasis of number of cells within a tissue [GO:0048873]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; lymphoid progenitor cell differentiation [GO:0002320]; male gonad development [GO:0008584]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; mesenchymal cell development [GO:0014031]; metanephros development [GO:0001656]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of calcium ion transport into cytosol [GO:0010523]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular pH reduction [GO:0032848]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of retinal cell programmed cell death [GO:0046671]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; organ growth [GO:0035265]; ossification [GO:0001503]; ovarian follicle development [GO:0001541]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pigment granule organization [GO:0048753]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuron maturation [GO:0014042]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of smooth muscle cell migration [GO:0014911]; post-embryonic development [GO:0009791]; protein dephosphorylation [GO:0006470]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glycoprotein biosynthetic process [GO:0010559]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of nitrogen utilization [GO:0006808]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; regulation of transmembrane transporter activity [GO:0022898]; regulation of viral genome replication [GO:0045069]; release of cytochrome c from mitochondria [GO:0001836]; renal system process [GO:0003014]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to iron ion [GO:0010039]; response to ischemia [GO:0002931]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; response to UV-B [GO:0010224]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]" comp141714_c0_seq1,2650,42.0755,0.38269034,468,1667,,2.00E-20,P34422,Dipeptidyl peptidase family member 6 (EC 3.4.14.-),Dipeptidyl peptidase family member 6 (EC 3.4.14.-),GO:0004177; GO:0016021; GO:0005886; GO:0006508; GO:0008236,aminopeptidase activity; integral to membrane; plasma membrane; proteolysis; serine-type peptidase activity,PF00326;,1.00E-70,CHOYP_BRAFLDRAFT_121562.1.1,,,,,,,DPF6_CAEEL,Caenorhabditis elegans, comp141715_c0_seq2,1945,29.7686,0.357108,5,0,,5.00E-11,Q9D5E4,Leucine-rich repeat-containing protein 48,Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48),GO:0005737,cytoplasm,,,,,,,,,,LRC48_MOUSE,Mus musculus (Mouse), comp141715_c0_seq3,1922,30.0208,0.35621675,3,0,,3.00E-81,Q8T888,"Dynein light chain 1, axonemal (Leucine-rich repeat dynein light chain)","Dynein light chain 1, axonemal (Leucine-rich repeat dynein light chain)",,,,2.00E-65,CHOYP_DNAL1.1.1,,,3.00E-67,AM854208.p.cg.6,5,,DNAL1_CIOIN,Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis), comp141717_c0_seq2,3457,33.6419,0.44811379,32,40,,6.00E-68,Q8CGC6,RNA-binding protein 28 (RNA-binding motif protein 28),RNA-binding protein 28 (RNA-binding motif protein 28),GO:0005794; GO:0003723; GO:0008380; GO:0006397; GO:0005730; GO:0000166; GO:0005681,Golgi apparatus; RNA binding; RNA splicing; mRNA processing; nucleolus; nucleotide binding; spliceosomal complex,PF00076;,,,,,,,,,RBM28_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp141717_c0_seq4,3012,31.9389,0.44723371,3,0,,2.00E-14,Q8CGC6,RNA-binding protein 28 (RNA-binding motif protein 28),RNA-binding protein 28 (RNA-binding motif protein 28),GO:0005794; GO:0003723; GO:0008380; GO:0006397; GO:0005730; GO:0000166; GO:0005681,Golgi apparatus; RNA binding; RNA splicing; mRNA processing; nucleolus; nucleotide binding; spliceosomal complex,PF00076;,,,,,,,,,RBM28_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp141719_c1_seq3,1232,39.1234,0.42460899,674,2773,,4.00E-52,Q06AA4,U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A),U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A),GO:0003723; GO:0000398; GO:0000166; GO:0017069; GO:0005681,"RNA binding; mRNA splicing, via spliceosome; nucleotide binding; snRNA binding; spliceosomal complex",PF00076;,1.00E-123,CHOYP_TTF2.1.1,,,,,,,SNRPA_PIG,Sus scrofa (Pig),"mRNA splicing, via spliceosome [GO:0000398]" comp141720_c0_seq1,1767,41.4827,0.54441896,12,229,,7.00E-178,Q17335,Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284),Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284),GO:0051903; GO:0004024; GO:0006066; GO:0005737; GO:0006069; GO:0008270,"S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; alcohol metabolic process; cytoplasm; ethanol oxidation; zinc ion binding",PF08240;PF00107;,6.00E-174,CHOYP_ADHX.1.1,,,,,,,ADHX_CAEEL,Caenorhabditis elegans,alcohol metabolic process [GO:0006066]; ethanol oxidation [GO:0006069] comp141720_c0_seq2,1158,37.4784,0.71216696,28,354,,2.00E-58,P30350,Alcohol dehydrogenase 1 (EC 1.1.1.1) (Fragment),Alcohol dehydrogenase 1 (EC 1.1.1.1) (Fragment),GO:0004022; GO:0005737; GO:0008270,alcohol dehydrogenase (NAD) activity; cytoplasm; zinc ion binding,PF00107;,,,2.00E-30,ruditapes2_c5635,,,,,ADH1_ANAPL,Anas platyrhynchos (Mallard) (Anas boschas), comp141720_c0_seq4,1916,39.8747,0.55788861,6,61,,0,P79896,Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284),Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284),GO:0051903; GO:0004022; GO:0005737; GO:0006069; GO:0008270,S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD) activity; cytoplasm; ethanol oxidation; zinc ion binding,PF08240;PF00107;,,,5.00E-72,ruditapes_c4275,7.00E-172,BQ427315.p.cg.6,4,,ADHX_SPAAU,Sparus aurata (Gilthead sea bream),ethanol oxidation [GO:0006069] comp141722_c0_seq1,2083,37.9261,0.43751363,2085,16179,,3.00E-92,Q5E9D0,Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta),Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta),GO:0046872; GO:0003743,metal ion binding; translation initiation factor activity,PF01873;,9.00E-97,CHOYP_AAEL_AAEL011527.1.1,2.00E-32,ruditapes_c7787,,,,,IF2B_BOVIN,Bos taurus (Bovine), comp141723_c1_seq3,2779,42.6412,0.41510765,95,229,,4.00E-64,Q9QX47,Protein SON (Negative regulatory element-binding protein) (NRE-binding protein),Protein SON (Negative regulatory element-binding protein) (NRE-binding protein),GO:0003677; GO:0003723; GO:0008380; GO:0000910; GO:0006397; GO:0000226; GO:0043066; GO:0016607; GO:0043484; GO:0051726; GO:0006355; GO:0006351,"DNA binding; RNA binding; RNA splicing; cytokinesis; mRNA processing; microtubule cytoskeleton organization; negative regulation of apoptotic process; nuclear speck; regulation of RNA splicing; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01585;,6.00E-50,CHOYP_SON.2.3,2.00E-53,ruditapes_c8592,,,,,SON_MOUSE,Mus musculus (Mouse),"microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp141725_c0_seq1,4793,31.6086,0.6074164,1582,592,,0,P67963,Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1),Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1),GO:0005524; GO:0016055; GO:0051301; GO:0000777; GO:0005737; GO:0005815; GO:0007067; GO:0016607; GO:0004674,ATP binding; Wnt receptor signaling pathway; cell division; condensed chromosome kinetochore; cytoplasm; microtubule organizing center; mitosis; nuclear speck; protein serine/threonine kinase activity,PF00069;,0,CHOYP_KC1A.2.2,6.00E-114,ruditapes_c16356,2.00E-69,CU682645.p.cg.6,7,,KC1A_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] comp141726_c0_seq2,1552,38.7887,0.44677809,1,55,,1.00E-17,Q86UT8,Coiled-coil domain-containing protein 84,Coiled-coil domain-containing protein 84,,,PF14968;,,,,,,,,,CCD84_HUMAN,Homo sapiens (Human), comp141727_c0_seq1,6641,43.5477,0.48415973,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,0,CHOYP_AKD1.3.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq10,5952,45.7325,0.48728604,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,0,CHOYP_AKD1.3.3,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq11,2305,46.8113,0.47948555,0,0,,1.00E-15,C4Z2V1,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737; GO:0008270,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm; zinc ion binding,PF05191;,1.00E-165,CHOYP_AKD1.1.3,,,,,,,KAD_EUBE2,Eubacterium eligens (strain ATCC 27750 / VPI C15-48),AMP salvage [GO:0044209] comp141727_c0_seq12,4438,45.8991,0.52674884,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,0,CHOYP_AKD1.3.3,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq13,5976,45.666,0.48693983,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,3.00E-165,CHOYP_AKD1.1.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq14,6138,45.6663,0.4903782,0,0,,5.00E-15,C4Z2V1,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737; GO:0008270,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm; zinc ion binding,PF05191;,0,CHOYP_AKD1.3.3,,,,,,,KAD_EUBE2,Eubacterium eligens (strain ATCC 27750 / VPI C15-48),AMP salvage [GO:0044209] comp141727_c0_seq15,6653,43.5894,0.48231932,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq16,5940,45.6902,0.48922577,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq17,5988,45.6413,0.48627326,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,0,CHOYP_AKD1.3.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq18,6114,45.7311,0.49081064,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,0,CHOYP_AKD1.3.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq19,4565,45.4326,0.53000432,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq2,4450,45.9101,0.52516285,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq20,2238,44.504,0.4461829,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq21,2467,46.818,0.48721453,0,0,,2.00E-15,C4Z2V1,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737; GO:0008270,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm; zinc ion binding,PF05191;,,,,,,,,,KAD_EUBE2,Eubacterium eligens (strain ATCC 27750 / VPI C15-48),AMP salvage [GO:0044209] comp141727_c0_seq23,6815,43.6831,0.48494063,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,0,CHOYP_AKD1.3.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq24,2459,46.889,0.48708057,0,0,,5.00E-13,C5BD16,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm,PF05191;,1.00E-165,CHOYP_AKD1.1.3,,,,,,,KAD_EDWI9,Edwardsiella ictaluri (strain 93-146),AMP salvage [GO:0044209] comp141727_c0_seq25,2479,46.7931,0.48482635,0,0,,2.00E-15,C4Z2V1,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737; GO:0008270,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm; zinc ion binding,PF05191;,,,,,,,,,KAD_EUBE2,Eubacterium eligens (strain ATCC 27750 / VPI C15-48),AMP salvage [GO:0044209] comp141727_c0_seq26,3285,45.3272,0.45643898,0,0,,1.00E-12,Q0C7Y1,Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate kinase cytosolic and mitochondrial) (Adenylate monophosphate kinase),Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate kinase cytosolic and mitochondrial) (Adenylate monophosphate kinase),GO:0006172; GO:0005524; GO:0006270; GO:0004017; GO:0005829; GO:0005758,ADP biosynthetic process; ATP binding; DNA replication initiation; adenylate kinase activity; cytosol; mitochondrial intermembrane space,PF05191;,0,CHOYP_AKD1.3.3,,,,,,,KAD1_ASPTN,Aspergillus terreus (strain NIH 2624 / FGSC A1156),ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; DNA replication initiation [GO:0006270] comp141727_c0_seq27,6779,43.7085,0.48694034,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq28,2285,46.7834,0.48479564,0,0,,4.00E-13,C5BD16,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm,PF05191;,1.00E-165,CHOYP_AKD1.1.3,,,,,,,KAD_EDWI9,Edwardsiella ictaluri (strain 93-146),AMP salvage [GO:0044209] comp141727_c0_seq3,6605,43.5882,0.48583533,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,0,CHOYP_AKD1.3.3,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq30,2447,46.8329,0.49096096,2,0,,2.00E-15,C4Z2V1,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737; GO:0008270,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm; zinc ion binding,PF05191;,,,,,,,,,KAD_EUBE2,Eubacterium eligens (strain ATCC 27750 / VPI C15-48),AMP salvage [GO:0044209] comp141727_c0_seq32,6150,45.6911,0.48899086,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,0,CHOYP_AKD1.3.3,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq33,2297,46.8437,0.48041424,0,0,,8.00E-17,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,1.00E-165,CHOYP_AKD1.1.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq35,3249,45.4294,0.45931702,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,0,CHOYP_AKD1.3.3,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq37,1619,45.9543,0.39017641,7,0,,4.00E-17,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,8.00E-166,CHOYP_AKD1.1.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq39,2202,44.6412,0.45054519,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq40,5230,42.8489,0.523066,0,0,,,,,,,,,0,CHOYP_AKD1.3.3,,,,,,,,, comp141727_c0_seq5,6617,43.6452,0.48385518,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,3.00E-165,CHOYP_AKD1.1.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq6,2317,46.8278,0.47652938,0,0,,4.00E-13,C5BD16,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm,PF05191;,1.00E-165,CHOYP_AKD1.1.3,,,,,,,KAD_EDWI9,Edwardsiella ictaluri (strain 93-146),AMP salvage [GO:0044209] comp141727_c0_seq7,6102,45.7227,0.49209368,0,0,,0,Q5TCS8,Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2),GO:0006757; GO:0006756; GO:0005524; GO:0061508; GO:0061566; GO:0061568; GO:0061571; GO:0061569; GO:0005737; GO:0006174; GO:0061565; GO:0061570; GO:0061567; GO:0006186; GO:0004550; GO:0050145; GO:0017111; GO:0005634,ADP phosphorylation; AMP phosphorylation; ATP binding; CDP phosphorylation; CMP phosphorylation; GDP phosphorylation; TDP phosphorylation; UDP phosphorylation; cytoplasm; dADP phosphorylation; dAMP phosphorylation; dCDP phosphorylation; dCMP phosphorylation; dGDP phosphorylation; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside-triphosphatase activity; nucleus,,,,,,,,,,AKD1_HUMAN,Homo sapiens (Human),AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] comp141727_c0_seq8,6803,43.6278,0.48712084,0,0,,3.00E-16,Q9FIJ7,"Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)","Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)",GO:0005524; GO:0004017; GO:0009570,ATP binding; adenylate kinase activity; chloroplast stroma,,0,CHOYP_AKD1.3.3,,,,,,,KADC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of energy homeostasis [GO:2000505] comp141727_c0_seq9,6767,43.6826,0.4885539,0,0,,6.00E-15,C4Z2V1,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737; GO:0008270,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm; zinc ion binding,PF05191;,0,CHOYP_AKD1.3.3,,,,,,,KAD_EUBE2,Eubacterium eligens (strain ATCC 27750 / VPI C15-48),AMP salvage [GO:0044209] comp141728_c0_seq1,3672,34.8584,0.50692538,1349,4658,,5.00E-180,Q64620,"Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) (Protein phosphatase V) (PP-V) [Cleaved into: Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed]","Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) (Protein phosphatase V) (PP-V) [Cleaved into: Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed]",GO:0007049; GO:0005737; GO:0046872; GO:0006470; GO:0004722,cell cycle; cytoplasm; metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00149;,0,CHOYP_PPP6.1.1,6.00E-11,ruditapes_c13481,,,,,PPP6_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; protein dephosphorylation [GO:0006470] comp141729_c1_seq1,1563,37.3001,0.4426939,1419,3906,,2.00E-92,P23965,"Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase)","Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase)",GO:0004165; GO:0006635; GO:0042802; GO:0005759; GO:0005739,dodecenoyl-CoA delta-isomerase activity; fatty acid beta-oxidation; identical protein binding; mitochondrial matrix; mitochondrion,PF00378;,2.00E-46,CHOYP_LOC100706747.1.1,,,,,,,ECI1_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation [GO:0006635] comp141731_c0_seq1,4863,44.746,0.42031212,325,403,,7.00E-104,Q1LUT1,Enhancer of mRNA-decapping protein 4,Enhancer of mRNA-decapping protein 4,GO:0000932; GO:0005634,cytoplasmic mRNA processing body; nucleus,PF16529;,1.00E-144,CHOYP_LOC100374995.1.3,,,,,,,EDC4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141731_c0_seq3,834,45.3237,0.58716894,7,5,,,,,,,,,2.00E-25,CHOYP_LOC100374995.1.3,,,,,,,,, comp141735_c0_seq3,2929,34.1072,0.52365214,34,395,,,,,,,,,1.00E-27,CHOYP_NEMVEDRAFT_V1G234225.1.1,,,,,,,,, comp141735_c0_seq6,2890,34.0484,0.51958377,80,627,,2.00E-87,Q5ZJF4,Peroxiredoxin-6 (EC 1.11.1.15),Peroxiredoxin-6 (EC 1.11.1.15),GO:0016023; GO:0016787; GO:0016042; GO:0005764; GO:0004601; GO:0051920,cytoplasmic membrane-bounded vesicle; hydrolase activity; lipid catabolic process; lysosome; peroxidase activity; peroxiredoxin activity,PF10417;PF00578;,1.00E-27,CHOYP_NEMVEDRAFT_V1G234225.1.1,1.00E-74,ruditapes2_c161,,,,,PRDX6_CHICK,Gallus gallus (Chicken),lipid catabolic process [GO:0016042] comp141737_c0_seq1,1300,42.3077,0.93610896,101,678,,3.00E-18,Q8BJK1,BTB/POZ domain-containing protein KCTD7,BTB/POZ domain-containing protein KCTD7,GO:0005829; GO:0005886; GO:0051260,cytosol; plasma membrane; protein homooligomerization,PF02214;,,,2.00E-11,ruditapes_c13795,,,,,KCTD7_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp141738_c0_seq1,1251,34.8521,0.53011572,310,1871,,8.00E-62,Q6P268,Phosducin-like protein 3 (Viral IAP-associated factor 1 homolog),Phosducin-like protein 3 (Viral IAP-associated factor 1 homolog),GO:0006915; GO:0005737,apoptotic process; cytoplasm,PF02114;,1.00E-36,CHOYP_PDCL3.1.1,,,,,,,PDCL3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; queuosine biosynthetic process [GO:0008616] comp141739_c0_seq2,1778,35.7143,0.59200753,130,868,,6.00E-94,P59999,Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC),Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC),GO:0034314; GO:0005885; GO:0030041; GO:0042995; GO:0005737,Arp2/3 complex-mediated actin nucleation; Arp2/3 protein complex; actin filament polymerization; cell projection; cytoplasm,PF05856;,4.00E-87,CHOYP_ARPC4.2.2,1.00E-67,ruditapes_c16447,,,,,ARPC4_MOUSE,Mus musculus (Mouse),actin filament polymerization [GO:0030041]; Arp2/3 complex-mediated actin nucleation [GO:0034314] comp141740_c0_seq1,3078,46.6212,1.05567645,26589,1947,,2.00E-25,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp141741_c1_seq2,1531,29.1313,0.77845562,0,0,,3.00E-15,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp141741_c1_seq3,1845,28.7263,0.71896162,0,2,,4.00E-15,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp141742_c0_seq1,3503,40.0799,0.3737792,96,1248,,4.00E-119,Q9NKW1,Peroxisomal multifunctional enzyme A (MFE-A) (MFE-1) [Includes: 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)],Peroxisomal multifunctional enzyme A (MFE-A) (MFE-1) [Includes: 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)],GO:0003857; GO:0006635; GO:0005777; GO:0032934,3-hydroxyacyl-CoA dehydrogenase activity; fatty acid beta-oxidation; peroxisome; sterol binding,PF00106;PF02036;,,,,,,,,,MFEA_DICDI,Dictyostelium discoideum (Slime mold),cAMP-mediated signaling [GO:0019933]; fatty acid beta-oxidation [GO:0006635]; sorocarp development [GO:0030587] comp141742_c0_seq2,2917,41.6524,0.34575941,3,32,,0,P97852,"Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]","Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]",GO:0033989; GO:0060009; GO:0008203; GO:0006635; GO:0016853; GO:0005739; GO:0005777; GO:0032934; GO:0030283; GO:0000038,"3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; Sertoli cell development; cholesterol metabolic process; fatty acid beta-oxidation; isomerase activity; mitochondrion; peroxisome; sterol binding; testosterone dehydrogenase [NAD(P)] activity; very long-chain fatty acid metabolic process",PF00106;PF01575;PF02036;,2.00E-175,CHOYP_DHB4.1.2,,,,,,,DHB4_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular response to organic cyclic compound [GO:0071407]; cholesterol metabolic process [GO:0008203]; fatty acid beta-oxidation [GO:0006635]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; response to steroid hormone [GO:0048545] comp141744_c0_seq1,3780,43.9683,0.28211908,3,0,,,,,,,,,1.00E-28,CHOYP_LOC100176721.4.6,,,,,,,,, comp141744_c0_seq2,3830,43.7598,0.28132181,8,0,,,,,,,,,4.00E-54,CHOYP_LOC100176721.5.6,,,,,,,,, comp141744_c0_seq3,1468,47.752,0.42745903,105,4,,1.00E-15,Q9W7R3,Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4),Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4),GO:0003824; GO:0032289; GO:0005737; GO:0007156; GO:0005887; GO:0016020; GO:0008152; GO:0048666; GO:0043005; GO:0005634; GO:2000543; GO:0031643; GO:0010976; GO:0048714; GO:0046982; GO:0042803; GO:0007165,catalytic activity; central nervous system myelin formation; cytoplasm; homophilic cell adhesion; integral to plasma membrane; membrane; metabolic process; neuron development; neuron projection; nucleus; positive regulation of gastrulation; positive regulation of myelination; positive regulation of neuron projection development; positive regulation of oligodendrocyte differentiation; protein heterodimerization activity; protein homodimerization activity; signal transduction,PF05593;PF06484;PF15636;,1.00E-36,CHOYP_LOC100176721.6.6,,,,,,,TEN4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axon guidance [GO:0007411]; central nervous system myelin formation [GO:0032289]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oligodendrocyte differentiation [GO:0048714]; self proteolysis [GO:0097264]; signal transduction [GO:0007165] comp141744_c0_seq5,3404,43.3314,0.27617494,0,0,,,,,,,,,3.00E-54,CHOYP_LOC100176721.5.6,,,,,,,,, comp141744_c1_seq1,2106,47.7208,0.3689451,0,0,,5.00E-20,Q80T91,Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11),Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11),GO:0016323; GO:0034109; GO:0016021; GO:0010842,basolateral plasma membrane; homotypic cell-cell adhesion; integral to membrane; retina layer formation,PF12661;PF00053;,,,,,,,,,MEG11_MOUSE,Mus musculus (Mouse),homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842] comp141744_c1_seq2,3819,47.0542,0.40257037,21,0,,3.00E-27,Q80YX1,Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C),Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C),GO:0005604; GO:0007155; GO:0005615; GO:0005614; GO:0060739; GO:0007528; GO:0014012; GO:0008284; GO:0010628; GO:0060740; GO:0045545,basement membrane; cell adhesion; extracellular space; interstitial matrix; mesenchymal-epithelial cell signaling involved in prostate gland development; neuromuscular junction development; peripheral nervous system axon regeneration; positive regulation of cell proliferation; positive regulation of gene expression; prostate gland epithelium morphogenesis; syndecan binding,PF07974;PF00147;PF00041;PF12661;,,,,,,,,,TENA_MOUSE,Mus musculus (Mouse),bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; wound healing [GO:0042060] comp141744_c1_seq3,3486,47.3609,0.39771236,5,0,,1.00E-22,P10039,Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C),Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF07974;PF00147;PF00041;PF12661;,,,,,,,,,TENA_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; regulation of cell proliferation [GO:0042127] comp141744_c1_seq4,2439,47.3965,0.38371682,6,0,,1.00E-27,Q80YX1,Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C),Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C),GO:0005604; GO:0007155; GO:0005615; GO:0005614; GO:0060739; GO:0007528; GO:0014012; GO:0008284; GO:0010628; GO:0060740; GO:0045545,basement membrane; cell adhesion; extracellular space; interstitial matrix; mesenchymal-epithelial cell signaling involved in prostate gland development; neuromuscular junction development; peripheral nervous system axon regeneration; positive regulation of cell proliferation; positive regulation of gene expression; prostate gland epithelium morphogenesis; syndecan binding,PF07974;PF00147;PF00041;PF12661;,,,,,,,,,TENA_MOUSE,Mus musculus (Mouse),bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; wound healing [GO:0042060] comp141744_c1_seq6,2207,46.1713,0.46496644,0,0,,5.00E-14,Q9W7R3,Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4),Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4),GO:0003824; GO:0032289; GO:0005737; GO:0007156; GO:0005887; GO:0016020; GO:0008152; GO:0048666; GO:0043005; GO:0005634; GO:2000543; GO:0031643; GO:0010976; GO:0048714; GO:0046982; GO:0042803; GO:0007165,catalytic activity; central nervous system myelin formation; cytoplasm; homophilic cell adhesion; integral to plasma membrane; membrane; metabolic process; neuron development; neuron projection; nucleus; positive regulation of gastrulation; positive regulation of myelination; positive regulation of neuron projection development; positive regulation of oligodendrocyte differentiation; protein heterodimerization activity; protein homodimerization activity; signal transduction,PF05593;PF06484;PF15636;,,,,,,,,,TEN4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axon guidance [GO:0007411]; central nervous system myelin formation [GO:0032289]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oligodendrocyte differentiation [GO:0048714]; self proteolysis [GO:0097264]; signal transduction [GO:0007165] comp141744_c1_seq7,827,45.3446,0.49783623,0,0,,1.00E-09,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp141747_c0_seq1,890,39.4382,0.29155796,13,96,,3.00E-06,Q8BJW7,Crossover junction endonuclease EME1 (EC 3.1.22.-),Crossover junction endonuclease EME1 (EC 3.1.22.-),GO:0003677; GO:0006310; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005730,DNA binding; DNA recombination; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleolus,PF02732;,,,,,,,,,EME1_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; response to intra-S DNA damage checkpoint signaling [GO:0072429] comp141747_c0_seq2,3025,41.8843,0.31913262,92,631,,1.00E-99,Q640B4,Crossover junction endonuclease MUS81 (EC 3.1.22.-),Crossover junction endonuclease MUS81 (EC 3.1.22.-),GO:0003677; GO:0006310; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA recombination; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF02732;,6.00E-50,CHOYP_LOC100180920.1.1,,,,,,,MUS81_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),DNA recombination [GO:0006310]; DNA repair [GO:0006281] comp141748_c1_seq1,2922,45.9959,0.39811956,263,363,,0,Q62388,Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),GO:0016303; GO:0005524; GO:0003677; GO:0000077; GO:0006975; GO:0006281; GO:0004677; GO:0031572; GO:0007420; GO:0007050; GO:0071480; GO:0000781; GO:0016023; GO:0007507; GO:0071044; GO:0016572; GO:0008630; GO:0042159; GO:0007094; GO:0030889; GO:0051402; GO:0005654; GO:0048599; GO:0018105; GO:0043517; GO:0043525; GO:0002331; GO:0047485; GO:0004674; GO:0090399; GO:0010212; GO:0001756; GO:0005819; GO:0000723,"1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA damage checkpoint; DNA damage induced protein phosphorylation; DNA repair; DNA-dependent protein kinase activity; G2 DNA damage checkpoint; brain development; cell cycle arrest; cellular response to gamma radiation; chromosome, telomeric region; cytoplasmic membrane-bounded vesicle; heart development; histone mRNA catabolic process; histone phosphorylation; intrinsic apoptotic signaling pathway in response to DNA damage; lipoprotein catabolic process; mitotic spindle assembly checkpoint; negative regulation of B cell proliferation; neuron apoptotic process; nucleoplasm; oocyte development; peptidyl-serine phosphorylation; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of neuron apoptotic process; pre-B cell allelic exclusion; protein N-terminus binding; protein serine/threonine kinase activity; replicative senescence; response to ionizing radiation; somitogenesis; spindle; telomere maintenance",PF02259;PF02260;PF00454;PF11640;,3.00E-110,CHOYP_LOC100369761.1.1,,,,,,,ATM_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to nitrosative stress [GO:0071500]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; establishment of RNA localization to telomere [GO:0097694]; female gamete generation [GO:0007292]; heart development [GO:0007507]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lipoprotein catabolic process [GO:0042159]; meiotic telomere clustering [GO:0045141]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of telomere capping [GO:1904354]; negative regulation of TORC1 signaling [GO:1904262]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; replicative senescence [GO:0090399]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; signal transduction involved in mitotic G2 DNA damage checkpoint [GO:0072434]; somitogenesis [GO:0001756]; telomere maintenance via telomerase [GO:0007004]; V(D)J recombination [GO:0033151]" comp141750_c0_seq2,1478,31.7997,0.59540001,29,86,,2.00E-11,Q502E5,Small integral membrane protein 8,Small integral membrane protein 8,GO:0016021,integral to membrane,PF14937;,,,5.00E-20,ruditapes2_c1118,,,,,CF162_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141752_c1_seq1,2353,45.6439,0.42727957,229,890,,0,Q90WU3,ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1),ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1),GO:0005524; GO:0008026; GO:0003677; GO:0032508; GO:0033677; GO:0003682; GO:0005737; GO:0006302; GO:0004527; GO:0006397; GO:0004518; GO:0005634; GO:0008143; GO:0006355; GO:0072669; GO:0003712; GO:0006351,"ATP binding; ATP-dependent helicase activity; DNA binding; DNA duplex unwinding; DNA/RNA helicase activity; chromatin binding; cytoplasm; double-strand break repair; exonuclease activity; mRNA processing; nuclease activity; nucleus; poly(A) RNA binding; regulation of transcription, DNA-dependent; tRNA-splicing ligase complex; transcription cofactor activity; transcription, DNA-dependent",PF00270;PF00271;PF00622;,0,CHOYP_DDX1.1.1,,,,,,,DDX1_CHICK,Gallus gallus (Chicken),"DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp141756_c0_seq1,1737,43.8112,0.5613224,117,490,,0,P08503,"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)","Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)",GO:0003995; GO:0033539; GO:0000062; GO:0050660; GO:0042802; GO:0016853; GO:0051793; GO:0005759; GO:0031966; GO:0051289; GO:0046688; GO:0042493; GO:0051384; GO:0007584,acyl-CoA dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty-acyl-CoA binding; flavin adenine dinucleotide binding; identical protein binding; isomerase activity; medium-chain fatty acid catabolic process; mitochondrial matrix; mitochondrial membrane; protein homotetramerization; response to copper ion; response to drug; response to glucocorticoid stimulus; response to nutrient,PF00441;PF02770;PF02771;,0,CHOYP_BRAFLDRAFT_98992.1.1,,,,,,,ACADM_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; medium-chain fatty acid catabolic process [GO:0051793]; protein homotetramerization [GO:0051289]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to nutrient [GO:0007584] comp141756_c0_seq3,1120,48.4821,0.59614356,37,190,,0,P08503,"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)","Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)",GO:0003995; GO:0033539; GO:0000062; GO:0050660; GO:0042802; GO:0016853; GO:0051793; GO:0005759; GO:0031966; GO:0051289; GO:0046688; GO:0042493; GO:0051384; GO:0007584,acyl-CoA dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty-acyl-CoA binding; flavin adenine dinucleotide binding; identical protein binding; isomerase activity; medium-chain fatty acid catabolic process; mitochondrial matrix; mitochondrial membrane; protein homotetramerization; response to copper ion; response to drug; response to glucocorticoid stimulus; response to nutrient,PF00441;PF02770;PF02771;,,,,,,,,,ACADM_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; medium-chain fatty acid catabolic process [GO:0051793]; protein homotetramerization [GO:0051289]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to nutrient [GO:0007584] comp141757_c0_seq1,2555,43.5616,0.60792821,0,0,,2.00E-21,Q9UHB6,LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),GO:0051015; GO:0051017; GO:0003785; GO:0005737; GO:0005925; GO:0030835; GO:0005886; GO:0031529; GO:0001725; GO:0008270,actin filament binding; actin filament bundle assembly; actin monomer binding; cytoplasm; focal adhesion; negative regulation of actin filament depolymerization; plasma membrane; ruffle organization; stress fiber; zinc ion binding,PF00412;,8.00E-48,CHOYP_UNC89.15.19,,,,,,,LIMA1_HUMAN,Homo sapiens (Human),actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529] comp141757_c0_seq10,3809,39.853,0.63157788,0,0,,1.00E-24,Q8BGB5,LIM domain-containing protein 2,LIM domain-containing protein 2,GO:0008270,zinc ion binding,PF00412;,,,,,,,,,LIMD2_MOUSE,Mus musculus (Mouse), comp141757_c0_seq13,400,33,0.5373928,3,32,,2.00E-07,Q86BA1,Protein-methionine sulfoxide oxidase Mical (EC 1.14.13.-) (Molecule interacting with CasL protein homolog),Protein-methionine sulfoxide oxidase Mical (EC 1.14.13.-) (Molecule interacting with CasL protein homolog),GO:0071949; GO:0070995; GO:0043914; GO:0003779; GO:0030042; GO:0030047; GO:0007411; GO:0005829; GO:0048813; GO:0016322; GO:0016709; GO:0005886; GO:0045214; GO:0019417; GO:0043195; GO:0008270,"FAD binding; NADPH oxidation; NADPH:sulfur oxidoreductase activity; actin binding; actin filament depolymerization; actin modification; axon guidance; cytosol; dendrite morphogenesis; neuron remodeling; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; plasma membrane; sarcomere organization; sulfur oxidation; terminal bouton; zinc ion binding",PF00307;PF12130;PF00412;,,,,,,,,,MICAL_DROME,Drosophila melanogaster (Fruit fly),actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin modification [GO:0030047]; axon guidance [GO:0007411]; dendrite morphogenesis [GO:0048813]; larval somatic muscle development [GO:0007526]; NADPH oxidation [GO:0070995]; neuron remodeling [GO:0016322]; oxidation-reduction process [GO:0055114]; regulation of neuron remodeling [GO:1904799]; sarcomere organization [GO:0045214]; sulfur oxidation [GO:0019417]; synapse assembly involved in innervation [GO:0060386] comp141757_c0_seq15,3779,39.693,0.64265255,0,0,,3.00E-21,Q9UHB6,LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),GO:0051015; GO:0051017; GO:0003785; GO:0005737; GO:0005925; GO:0030835; GO:0005886; GO:0031529; GO:0001725; GO:0008270,actin filament binding; actin filament bundle assembly; actin monomer binding; cytoplasm; focal adhesion; negative regulation of actin filament depolymerization; plasma membrane; ruffle organization; stress fiber; zinc ion binding,PF00412;,,,,,,,,,LIMA1_HUMAN,Homo sapiens (Human),actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529] comp141757_c0_seq17,2309,43.6553,0.56325259,2,0,,5.00E-25,Q8BGB5,LIM domain-containing protein 2,LIM domain-containing protein 2,GO:0008270,zinc ion binding,PF00412;,7.00E-48,CHOYP_UNC89.15.19,,,,,,,LIMD2_MOUSE,Mus musculus (Mouse), comp141757_c0_seq2,2585,43.7137,0.61172869,0,0,,6.00E-25,Q8BGB5,LIM domain-containing protein 2,LIM domain-containing protein 2,GO:0008270,zinc ion binding,PF00412;,8.00E-48,CHOYP_UNC89.15.19,,,,,,,LIMD2_MOUSE,Mus musculus (Mouse), comp141757_c0_seq3,2139,43.7588,0.5562984,0,0,,,,,,,,,3.00E-33,CHOYP_LOC100746973.1.2,,,,,,,,, comp141757_c0_seq6,3692,39.8158,0.62637933,0,0,,3.00E-21,Q9UHB6,LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),GO:0051015; GO:0051017; GO:0003785; GO:0005737; GO:0005925; GO:0030835; GO:0005886; GO:0031529; GO:0001725; GO:0008270,actin filament binding; actin filament bundle assembly; actin monomer binding; cytoplasm; focal adhesion; negative regulation of actin filament depolymerization; plasma membrane; ruffle organization; stress fiber; zinc ion binding,PF00412;,,,,,,,,,LIMA1_HUMAN,Homo sapiens (Human),actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529] comp141757_c0_seq7,3722,39.9785,0.61535951,0,0,,1.00E-24,Q8BGB5,LIM domain-containing protein 2,LIM domain-containing protein 2,GO:0008270,zinc ion binding,PF00412;,,,,,,,,,LIMD2_MOUSE,Mus musculus (Mouse), comp141757_c0_seq9,2282,43.4706,0.5762767,0,0,,1.00E-21,Q9UHB6,LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm),GO:0051015; GO:0051017; GO:0003785; GO:0005737; GO:0005925; GO:0030835; GO:0005886; GO:0031529; GO:0001725; GO:0008270,actin filament binding; actin filament bundle assembly; actin monomer binding; cytoplasm; focal adhesion; negative regulation of actin filament depolymerization; plasma membrane; ruffle organization; stress fiber; zinc ion binding,PF00412;,7.00E-48,CHOYP_UNC89.15.19,,,,,,,LIMA1_HUMAN,Homo sapiens (Human),actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529] comp141760_c1_seq1,3539,38.1746,0.57622845,5333,389,,3.00E-28,Q96M91,Coiled-coil domain-containing protein 11,Cilia- and flagella-associated protein 53 (Coiled-coil domain-containing protein 11),,,,1.00E-147,CHOYP_LOC100368885.1.1,,,,,,,CCD11_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341] comp141761_c0_seq1,2310,42.3377,0.33140169,1047,95,,1.00E-121,Q9ES07,"Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2)","Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2)",GO:0016021; GO:0015198; GO:0015031; GO:0015293,integral to membrane; oligopeptide transporter activity; protein transport; symporter activity,PF00854;,7.00E-61,CHOYP_LOC587947.1.1,,,,,,,S15A2_MOUSE,Mus musculus (Mouse),oligopeptide transport [GO:0006857]; protein transport [GO:0015031] comp141762_c0_seq1,1745,32.3209,0.48749302,11,77,,2.00E-98,A7SM54,Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1),Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1),,,PF08694;,3.00E-115,CHOYP_UFC1.1.2,,,,,,,UFC1_NEMVE,Nematostella vectensis (Starlet sea anemone), comp141765_c1_seq1,1798,32.9255,0.32974395,449,2930,,3.00E-20,Q5ZMM5,Zinc finger protein 706,Zinc finger protein 706,GO:0046872,metal ion binding,PF04419;,4.00E-24,CHOYP_ZN706.1.2,8.00E-50,ruditapes_c2200,,,,,ZN706_CHICK,Gallus gallus (Chicken),"negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of translation [GO:0006417]" comp141767_c0_seq2,1277,35.7087,0.51882958,0,0,,8.00E-48,P07347,N-terminal acetyltransferase A complex catalytic subunit ARD1 (NatA complex subunit ARD1) (EC 2.3.1.88) (Arrest-defective protein 1),N-terminal acetyltransferase A complex catalytic subunit ARD1 (NatA complex subunit ARD1) (EC 2.3.1.88) (Arrest-defective protein 1),GO:0006474; GO:0031415; GO:0016573; GO:0004596,N-terminal protein amino acid acetylation; NatA complex; histone acetylation; peptide alpha-N-acetyltransferase activity,PF00583;,,,,,,,,,ARD1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),histone acetylation [GO:0016573]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-serine acetylation [GO:0017198]; N-terminal protein amino acid acetylation [GO:0006474]; N-terminal protein amino acid propionylation [GO:0061606] comp141767_c0_seq5,1248,35.9776,0.49832461,0,0,,1.00E-94,Q9QY36,N-alpha-acetyltransferase 10 (EC 2.3.1.-) (EC 2.3.1.88) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (NatA catalytic subunit),N-alpha-acetyltransferase 10 (EC 2.3.1.-) (EC 2.3.1.88) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (NatA catalytic subunit Naa10),GO:0008080; GO:0006474; GO:0005737; GO:0005634; GO:0004596; GO:0043022,N-acetyltransferase activity; N-terminal protein amino acid acetylation; cytoplasm; nucleus; peptide alpha-N-acetyltransferase activity; ribosome binding,PF00583;,5.00E-104,CHOYP_LOC101165304.1.1,,,,,,,NAA10_MOUSE,Mus musculus (Mouse),internal protein amino acid acetylation [GO:0006475]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-serine acetylation [GO:0017198]; N-terminal protein amino acid acetylation [GO:0006474] comp141768_c0_seq1,2325,42.4516,0.70736291,979,3081,,2.00E-60,Q8K385,Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),GO:0000293; GO:0016021; GO:0046872,ferric-chelate reductase activity; integral to membrane; metal ion binding,PF03351;PF02014;,,,,,,,,,FRRS1_MOUSE,Mus musculus (Mouse), comp141769_c0_seq2,1858,35.8988,1.08878048,1,2105,female>male,1.00E-22,P61315,"Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)","Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)",GO:0032580; GO:0009058; GO:0001733; GO:0016021,Golgi cisterna membrane; biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane,PF06990;,,,,,,,,,G3ST3_MOUSE,Mus musculus (Mouse),glycolipid biosynthetic process [GO:0009247] comp141770_c1_seq1,2759,42.7329,0.5409301,760,3508,,6.00E-70,Q9HGQ2,Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4a (EC 2.1.1.-) (tRNA (cytosine-5-)-methyltransferase trm4a),Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4a (EC 2.1.1.-) (tRNA (cytosine-5-)-methyltransferase trm4a),GO:0005829; GO:0005634; GO:0016428; GO:0000049; GO:0030488,cytosol; nucleus; tRNA (cytosine-5-)-methyltransferase activity; tRNA binding; tRNA methylation,PF01189;,,,,,,,,,NCL1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),tRNA methylation [GO:0030488] comp141770_c1_seq2,2840,42.9225,0.56662577,1692,6584,,1.00E-82,Q28E61,tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOL1/NOP2/Sun domain family member 2),tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOL1/NOP2/Sun domain family member 2),GO:0005737; GO:0005730; GO:0016428; GO:0000049,cytoplasm; nucleolus; tRNA (cytosine-5-)-methyltransferase activity; tRNA binding,PF01189;,,,,,,,,,NSUN2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),tRNA methylation [GO:0030488] comp141772_c0_seq1,1658,36.9723,0.62387207,10,0,,,,,,,,,4.00E-36,CHOYP_TWF1.1.1,,,,,,,,, comp141772_c0_seq3,2252,35.4352,0.65694721,75,428,,5.00E-121,Q68F50,Twinfilin-1,Twinfilin-1,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF00241;,,,,,,,,,TWF1_XENLA,Xenopus laevis (African clawed frog),negative regulation of actin filament polymerization [GO:0030837] comp141772_c0_seq4,1606,37.1731,0.60104067,0,0,,,,,,,,,4.00E-36,CHOYP_TWF1.1.1,,,,,,,,, comp141772_c0_seq5,3983,33.7183,0.55156401,70,170,,3.00E-116,Q68F50,Twinfilin-1,Twinfilin-1,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF00241;,,,,,,,,,TWF1_XENLA,Xenopus laevis (African clawed frog),negative regulation of actin filament polymerization [GO:0030837] comp141773_c0_seq2,958,41.2317,0.45909624,90,390,,8.00E-34,Q8NE22,SET domain-containing protein 9 (EC 2.1.1.-),SET domain-containing protein 9 (EC 2.1.1.-),GO:0008168,methyltransferase activity,,,,,,,,,,SETD9_HUMAN,Homo sapiens (Human),regulation of signal transduction by p53 class mediator [GO:1901796] comp141774_c1_seq1,1768,40.8937,0.53430881,765,940,,0,Q8N3I7,Bardet-Biedl syndrome 5 protein,Bardet-Biedl syndrome 5 protein,GO:0034464; GO:0060170; GO:0005737; GO:0001947; GO:0032402; GO:0005932; GO:0044458; GO:0032266; GO:0050896; GO:0007601,BBSome; cilium membrane; cytoplasm; heart looping; melanosome transport; microtubule basal body; motile cilium assembly; phosphatidylinositol-3-phosphate binding; response to stimulus; visual perception,PF07289;,7.00E-173,CHOYP_BBS5.1.1,,,3.00E-154,AM857935.p.cg.6,5,male gonad,BBS5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; heart looping [GO:0001947]; intracellular transport [GO:0046907]; melanosome transport [GO:0032402]; motile cilium assembly [GO:0044458]; protein transport [GO:0015031]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp141776_c3_seq1,1873,34.0096,0.63215353,612,780,,3.00E-25,Q13542,Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2),Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2),GO:0019933; GO:0008286; GO:0045947; GO:0006412,cAMP-mediated signaling; insulin receptor signaling pathway; negative regulation of translational initiation; translation,PF05456;,,,3.00E-49,ruditapes_c16733,,,,,4EBP2_HUMAN,Homo sapiens (Human),cAMP-mediated signaling [GO:0019933]; insulin receptor signaling pathway [GO:0008286]; memory [GO:0007613]; modulation of synaptic transmission [GO:0050804]; negative regulation of translational initiation [GO:0045947]; regulation of synaptic plasticity [GO:0048167]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; translation [GO:0006412] comp141777_c0_seq1,2027,44.8939,0.52966321,14,9,,1.00E-33,Q9P6L5,Endocytosis protein end4 (SLA2 protein homolog),Endocytosis protein end4 (SLA2 protein homolog),GO:0070314; GO:0030479; GO:0051519; GO:0051285; GO:0032153; GO:0034613; GO:0006995; GO:0030866; GO:0006897; GO:0030950; GO:0071852; GO:0031580; GO:0005546; GO:0030674,"G1 to G0 transition; actin cortical patch; activation of bipolar cell growth; cell cortex of cell tip; cell division site; cellular protein localization; cellular response to nitrogen starvation; cortical actin cytoskeleton organization; endocytosis; establishment or maintenance of actin cytoskeleton polarity; fungal-type cell wall organization or biogenesis; membrane raft distribution; phosphatidylinositol-4,5-bisphosphate binding; protein binding, bridging",PF07651;PF01608;,,,,,,,,,SLA2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),actin cytoskeleton organization [GO:0030036]; activation of bipolar cell growth [GO:0051519]; cellular protein localization [GO:0034613]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950] comp141777_c0_seq3,2082,44.8607,0.52660125,26,11,,2.00E-15,Q9Y490,Talin-1,Talin-1,GO:0015629; GO:0006987; GO:0007411; GO:0007155; GO:0009986; GO:0005911; GO:0007043; GO:0007044; GO:0044267; GO:0005813; GO:0030866; GO:0007016; GO:0005829; GO:0070062; GO:0005925; GO:0043231; GO:0006936; GO:0005886; GO:0030168; GO:0002576; GO:0001726; GO:0032587; GO:0005200,actin cytoskeleton; activation of signaling protein activity involved in unfolded protein response; axon guidance; cell adhesion; cell surface; cell-cell junction; cell-cell junction assembly; cell-substrate junction assembly; cellular protein metabolic process; centrosome; cortical actin cytoskeleton organization; cytoskeletal anchoring at plasma membrane; cytosol; extracellular vesicular exosome; focal adhesion; intracellular membrane-bounded organelle; muscle contraction; plasma membrane; platelet activation; platelet degranulation; ruffle; ruffle membrane; structural constituent of cytoskeleton,PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;,,,,,,,,,TLN1_HUMAN,Homo sapiens (Human),cell-cell junction assembly [GO:0007043]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; IRE1-mediated unfolded protein response [GO:0036498]; movement of cell or subcellular component [GO:0006928]; muscle contraction [GO:0006936]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; viral process [GO:0016032] comp141777_c2_seq1,1617,43.9703,0.6322936,115,55,,3.00E-141,O00291,Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I),Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I),GO:0005794; GO:0006919; GO:0097190; GO:0030154; GO:0030276; GO:0048268; GO:0030136; GO:0030665; GO:0005856; GO:0006897; GO:0012505; GO:0016020; GO:0005634; GO:0035091; GO:0048260; GO:0006355; GO:0005200; GO:0006351,"Golgi apparatus; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; cell differentiation; clathrin binding; clathrin coat assembly; clathrin-coated vesicle; clathrin-coated vesicle membrane; cytoskeleton; endocytosis; endomembrane system; membrane; nucleus; phosphatidylinositol binding; positive regulation of receptor-mediated endocytosis; regulation of transcription, DNA-dependent; structural constituent of cytoskeleton; transcription, DNA-dependent",PF07651;PF16515;PF01608;,4.00E-113,CHOYP_HIP1.1.1,,,,,,,HIP1_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of apoptotic process [GO:0042981]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141781_c0_seq1,1653,42.2263,0.54174322,108,246,,1.00E-24,Q2HJ46,E3 ubiquitin-protein ligase RNF8 (EC 6.3.2.-) (RING finger protein 8),E3 ubiquitin-protein ligase RNF8 (EC 6.3.2.-) (RING finger protein 8),GO:0051301; GO:0003682; GO:0000781; GO:0006303; GO:0070535; GO:0033523; GO:0042393; GO:0043486; GO:0045190; GO:0030496; GO:0007067; GO:0045900; GO:0005634; GO:0045739; GO:0070936; GO:0051865; GO:0042803; GO:0010212; GO:0035861; GO:0007286; GO:0000151; GO:0006511; GO:0004842; GO:0008270,"cell division; chromatin binding; chromosome, telomeric region; double-strand break repair via nonhomologous end joining; histone H2A K63-linked ubiquitination; histone H2B ubiquitination; histone binding; histone exchange; isotype switching; midbody; mitosis; negative regulation of translational elongation; nucleus; positive regulation of DNA repair; protein K48-linked ubiquitination; protein autoubiquitination; protein homodimerization activity; response to ionizing radiation; site of double-strand break; spermatid development; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding",PF00498;PF00097;,1.00E-17,CHOYP_LOC100372947.1.1,,,,,,,RNF8_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; isotype switching [GO:0045190]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141785_c4_seq1,2830,40.212,0.4942882,28,9,,0,Q9VFC8,Putative glycogen [starch] synthase (EC 2.4.1.11),Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase),GO:0004373; GO:0005978,glycogen (starch) synthase activity; glycogen biosynthetic process,PF05693;,,,,,,,,,GYS_DROME,Drosophila melanogaster (Fruit fly),cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744] comp141785_c4_seq2,2901,40.3309,0.49605528,17,16,,,,,,,,,0,CHOYP_LOC100368259.1.1,,,,,,,,, comp141785_c4_seq3,2025,43.4074,0.50714991,4,0,,,,,,,,,0,CHOYP_LOC100368259.1.1,,,,,,,,, comp141786_c0_seq1,3700,43.6486,0.42803115,802,2564,,7.00E-134,Q6NRC9,Leucine-rich repeat and coiled-coil domain-containing protein 1,Leucine-rich repeat and coiled-coil domain-containing protein 1,GO:0051301; GO:0005814; GO:0007067,cell division; centriole; mitosis,PF12799;,5.00E-109,CHOYP_LOC100553117.1.1,,,,,,,LRCC1_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp141786_c0_seq2,1877,43.7933,0.40100369,0,11,,2.00E-07,P22194,Protein phosphatase 1 regulatory subunit SDS22,Protein phosphatase 1 regulatory subunit SDS22,GO:0051301; GO:0005829; GO:0051457; GO:0007067; GO:0005634; GO:1901970; GO:0071862; GO:0000164; GO:0030071; GO:0009966,cell division; cytosol; maintenance of protein location in nucleus; mitosis; nucleus; positive regulation of mitotic sister chromatid separation; protein phosphatase type 1 activator activity; protein phosphatase type 1 complex; regulation of mitotic metaphase/anaphase transition; regulation of signal transduction,PF12799;,,,,,,,,,SDS22_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of mitotic sister chromatid separation [GO:1901970]; regulation of phosphoprotein phosphatase activity [GO:0043666]; signal transduction [GO:0007165] comp141787_c1_seq2,3002,35.3098,0.47532237,88,581,,9.00E-121,Q13510,Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta],Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta],GO:0008219; GO:0017040; GO:0006672; GO:0006687; GO:0030324; GO:0043202; GO:0010033; GO:0044281,cell death; ceramidase activity; ceramide metabolic process; glycosphingolipid metabolic process; lung development; lysosomal lumen; response to organic substance; small molecule metabolic process,PF02275;PF15508;,,,,,,,,,ASAH1_HUMAN,Homo sapiens (Human),ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687] comp141787_c1_seq3,2556,37.0501,0.48346936,17,160,,3.00E-122,Q13510,Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta],Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta],GO:0008219; GO:0017040; GO:0006672; GO:0006687; GO:0030324; GO:0043202; GO:0010033; GO:0044281,cell death; ceramidase activity; ceramide metabolic process; glycosphingolipid metabolic process; lung development; lysosomal lumen; response to organic substance; small molecule metabolic process,PF02275;PF15508;,5.00E-76,CHOYP_LOC101065149.1.1,,,,,,,ASAH1_HUMAN,Homo sapiens (Human),ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687] comp141788_c0_seq2,2393,42.7497,0.5259106,137,164,,0,Q3URE1,"Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)","Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)",GO:0005524; GO:0006633; GO:0090410; GO:0090409; GO:0005739,ATP binding; fatty acid biosynthetic process; malonate catabolic process; malonyl-CoA synthetase activity; mitochondrion,PF00501;PF13193;,1.00E-14,CHOYP_ACSF3.1.1,,,,,,,ACSF3_MOUSE,Mus musculus (Mouse),fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; malonate catabolic process [GO:0090410] comp141788_c0_seq9,1610,43.5404,0.4553119,2,8,,4.00E-148,Q3URE1,"Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)","Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)",GO:0005524; GO:0006633; GO:0090410; GO:0090409; GO:0005739,ATP binding; fatty acid biosynthetic process; malonate catabolic process; malonyl-CoA synthetase activity; mitochondrion,PF00501;PF13193;,6.00E-15,CHOYP_ACSF3.1.1,,,,,,,ACSF3_MOUSE,Mus musculus (Mouse),fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; malonate catabolic process [GO:0090410] comp141789_c2_seq1,2661,36.3773,0.47773165,11,28,,9.00E-80,Q9SB48,NADPH--cytochrome P450 reductase 1 (EC 1.6.2.4),NADPH--cytochrome P450 reductase 1 (CPR 1) (P450R 1) (EC 1.6.2.4),GO:0010181; GO:0003958; GO:0005829; GO:0005783; GO:0005789; GO:0005506; GO:0009698; GO:0009737; GO:0006979,FMN binding; NADPH-hemoprotein reductase activity; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; iron ion binding; phenylpropanoid metabolic process; response to abscisic acid stimulus; response to oxidative stress,PF00667;PF00258;PF00175;,,,,,,,,,NCPR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),phenylpropanoid metabolic process [GO:0009698]; response to abscisic acid [GO:0009737]; response to oxidative stress [GO:0006979] comp141789_c2_seq4,918,45.3159,0.4679799,0,0,,7.00E-149,P16435,NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4),NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4),GO:0010181; GO:0050661; GO:0003958; GO:0009437; GO:0090346; GO:0071372; GO:0071375; GO:0004128; GO:0070988; GO:0009055; GO:0005783; GO:0005789; GO:0019395; GO:0050660; GO:0009812; GO:0016787; GO:0018393; GO:0005506; GO:0047726; GO:0005739; GO:0043066; GO:0043154; GO:0060192; GO:0043602; GO:0046210; GO:0045542; GO:0032332; GO:0032770; GO:0045880; GO:0090031; GO:0003420; GO:0042493; GO:0007584,"FMN binding; NADP binding; NADPH-hemoprotein reductase activity; carnitine metabolic process; cellular organofluorine metabolic process; cellular response to follicle-stimulating hormone stimulus; cellular response to peptide hormone stimulus; cytochrome-b5 reductase activity, acting on NAD(P)H; demethylation; electron carrier activity; endoplasmic reticulum; endoplasmic reticulum membrane; fatty acid oxidation; flavin adenine dinucleotide binding; flavonoid metabolic process; hydrolase activity; internal peptidyl-lysine acetylation; iron ion binding; iron-cytochrome-c reductase activity; mitochondrion; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of lipase activity; nitrate catabolic process; nitric oxide catabolic process; positive regulation of cholesterol biosynthetic process; positive regulation of chondrocyte differentiation; positive regulation of monooxygenase activity; positive regulation of smoothened signaling pathway; positive regulation of steroid hormone biosynthetic process; regulation of growth plate cartilage chondrocyte proliferation; response to drug; response to nutrient",PF00667;PF00258;PF00175;,,,,,,,,,NCPR_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805] comp141789_c2_seq5,2574,35.9751,0.45676282,1,20,,2.00E-50,Q6LM58,Sulfite reductase [NADPH] flavoprotein alpha-component (SiR-FP) (EC 1.8.1.2),Sulfite reductase [NADPH] flavoprotein alpha-component (SiR-FP) (EC 1.8.1.2),GO:0010181; GO:0019344; GO:0050660; GO:0070814; GO:0005506; GO:0000103; GO:0004783,FMN binding; cysteine biosynthetic process; flavin adenine dinucleotide binding; hydrogen sulfide biosynthetic process; iron ion binding; sulfate assimilation; sulfite reductase (NADPH) activity,PF00667;PF00258;PF00175;,,,,,,,,,CYSJ_PHOPR,Photobacterium profundum (strain SS9),cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103] comp141789_c2_seq6,919,44.8313,0.45432153,14,6,,5.00E-156,P16435,NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4),NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4),GO:0010181; GO:0050661; GO:0003958; GO:0009437; GO:0090346; GO:0071372; GO:0071375; GO:0004128; GO:0070988; GO:0009055; GO:0005783; GO:0005789; GO:0019395; GO:0050660; GO:0009812; GO:0016787; GO:0018393; GO:0005506; GO:0047726; GO:0005739; GO:0043066; GO:0043154; GO:0060192; GO:0043602; GO:0046210; GO:0045542; GO:0032332; GO:0032770; GO:0045880; GO:0090031; GO:0003420; GO:0042493; GO:0007584,"FMN binding; NADP binding; NADPH-hemoprotein reductase activity; carnitine metabolic process; cellular organofluorine metabolic process; cellular response to follicle-stimulating hormone stimulus; cellular response to peptide hormone stimulus; cytochrome-b5 reductase activity, acting on NAD(P)H; demethylation; electron carrier activity; endoplasmic reticulum; endoplasmic reticulum membrane; fatty acid oxidation; flavin adenine dinucleotide binding; flavonoid metabolic process; hydrolase activity; internal peptidyl-lysine acetylation; iron ion binding; iron-cytochrome-c reductase activity; mitochondrion; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of lipase activity; nitrate catabolic process; nitric oxide catabolic process; positive regulation of cholesterol biosynthetic process; positive regulation of chondrocyte differentiation; positive regulation of monooxygenase activity; positive regulation of smoothened signaling pathway; positive regulation of steroid hormone biosynthetic process; regulation of growth plate cartilage chondrocyte proliferation; response to drug; response to nutrient",PF00667;PF00258;PF00175;,6.00E-177,CHOYP_LOC594665.1.1,,,,,,,NCPR_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805] comp141791_c0_seq1,1394,39.0961,0.96528054,74,220,,1.00E-10,Q54ND5,"Multiple inositol polyphosphate phosphatase 1 (Ddmipp1) (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)","Multiple inositol polyphosphate phosphatase 1 (Ddmipp1) (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)",GO:0003993; GO:0034417; GO:0005829; GO:0006007; GO:0052826; GO:0016021,acid phosphatase activity; bisphosphoglycerate 3-phosphatase activity; cytosol; glucose catabolic process; inositol hexakisphosphate 2-phosphatase activity; integral to membrane,PF00328;,,,,,,,,,MINP1_DICDI,Dictyostelium discoideum (Slime mold),glucose catabolic process [GO:0006007] comp141791_c0_seq2,1412,38.9518,1.01736051,32,193,,2.00E-33,O35217,"Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)","Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)",GO:0003993; GO:0034417; GO:0005788; GO:0052826; GO:0030351; GO:0030352; GO:0048015,"acid phosphatase activity; bisphosphoglycerate 3-phosphatase activity; endoplasmic reticulum lumen; inositol hexakisphosphate 2-phosphatase activity; inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity; phosphatidylinositol-mediated signaling",PF00328;,,,,,,,,,MINP1_RAT,Rattus norvegicus (Rat),phosphatidylinositol-mediated signaling [GO:0048015] comp141792_c1_seq1,840,35.2381,0.20078336,185,961,,7.00E-15,A1L2P2,Small integral membrane protein 12-A,Small integral membrane protein 12-A,GO:0016021,integral to membrane,PF15990;,,,,,,,,,C212A_XENLA,Xenopus laevis (African clawed frog), comp141796_c0_seq1,3142,37.492,0.45184946,0,142,,6.00E-34,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141796_c0_seq2,3127,37.8318,0.43683342,2,193,,2.00E-33,Q9NPC7,Myoneurin (Zinc finger and BTB domain-containing protein 31),Myoneurin (Zinc finger and BTB domain-containing protein 31),GO:0003677; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp141801_c0_seq1,1513,43.2915,0.4664988,72,186,,4.00E-176,Q2TBV5,General transcription factor IIH subunit 2 (General transcription factor IIH polypeptide 2),General transcription factor IIH subunit 2 (General transcription factor IIH polypeptide 2),GO:0000439; GO:0005675; GO:0006289; GO:0006468; GO:0006355; GO:0006366; GO:0008270,"core TFIIH complex; holo TFIIH complex; nucleotide-excision repair; protein phosphorylation; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; zinc ion binding",PF07975;PF04056;,2.00E-96,CHOYP_BRAFLDRAFT_282199.1.1,,,,,,,TF2H2_BOVIN,Bos taurus (Bovine),"nucleotide-excision repair [GO:0006289]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp141803_c0_seq1,2731,37.6053,0.4280136,2868,22649,,0,P80315,T-complex protein 1 subunit delta (TCP-1-delta) (A45) (CCT-delta),T-complex protein 1 subunit delta (TCP-1-delta) (A45) (CCT-delta),GO:0005524; GO:0007339; GO:0044297; GO:0005813; GO:0005832; GO:0042470; GO:0005874; GO:0006457; GO:0002199,ATP binding; binding of sperm to zona pellucida; cell body; centrosome; chaperonin-containing T-complex; melanosome; microtubule; protein folding; zona pellucida receptor complex,PF00118;,0,CHOYP_TCPD.1.1,4.00E-31,ruditapes_c28442,1.00E-91,DV736591.p.cg.6,9,,TCPD_MOUSE,Mus musculus (Mouse),binding of sperm to zona pellucida [GO:0007339]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998] comp141805_c0_seq1,3078,37.4594,0.37812782,13,11,,,,,,,,,5.00E-39,CHOYP_LOC100891466.9.10,,,,,,,,, comp141805_c0_seq5,1613,36.3918,0.42636904,0,0,,,,,,,,,2.00E-16,CHOYP_LOC100891466.1.10,,,,,,,,, comp141806_c2_seq1,805,37.6398,0.35487903,86,792,,4.00E-55,Q6PBF7,ER membrane protein complex subunit 4 (Transmembrane protein 85),ER membrane protein complex subunit 4 (Transmembrane protein 85),GO:0072546,ER membrane protein complex,PF06417;,1.00E-52,CHOYP_BRAFLDRAFT_126700.2.2,3.00E-108,ruditapes_c7419,,,,,EMC4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141807_c0_seq1,2797,45.1555,0.6994365,7,2,,1.00E-174,O70161,Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma),Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma),GO:0016308; GO:0005524; GO:0007409; GO:0006935; GO:0005737; GO:0007016; GO:0012505; GO:0006887; GO:0005925; GO:0001891; GO:0006909; GO:0070527; GO:0032587; GO:1990147; GO:0001931,1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; axonogenesis; chemotaxis; cytoplasm; cytoskeletal anchoring at plasma membrane; endomembrane system; exocytosis; focal adhesion; phagocytic cup; phagocytosis; platelet aggregation; ruffle membrane; talin binding; uropod,PF01504;,,,,,,,,,PI51C_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; chemotaxis [GO:0006935]; cytoskeletal anchoring at plasma membrane [GO:0007016]; exocytosis [GO:0006887]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol metabolic process [GO:0046488]; platelet aggregation [GO:0070527] comp141807_c0_seq2,1609,43.5053,0.67915659,0,0,,7.00E-179,O60331,Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma),Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma),GO:0016308; GO:0005524; GO:0030036; GO:0034333; GO:0007411; GO:0016337; GO:0072583; GO:0005829; GO:0012505; GO:0005925; GO:0030593; GO:0005634; GO:0001891; GO:0006909; GO:0006661; GO:0046854; GO:0032587; GO:0044281; GO:0048488; GO:0016079; GO:0001931,1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; actin cytoskeleton organization; adherens junction assembly; axon guidance; cell-cell adhesion; clathrin-mediated endocytosis; cytosol; endomembrane system; focal adhesion; neutrophil chemotaxis; nucleus; phagocytic cup; phagocytosis; phosphatidylinositol biosynthetic process; phosphatidylinositol phosphorylation; ruffle membrane; small molecule metabolic process; synaptic vesicle endocytosis; synaptic vesicle exocytosis; uropod,PF01504;,4.00E-132,CHOYP_LOC663424.1.2,,,,,,,PI51C_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; adherens junction assembly [GO:0034333]; clathrin-mediated endocytosis [GO:0072583]; neutrophil chemotaxis [GO:0030593]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079] comp141807_c0_seq4,2812,45.128,0.70354206,0,0,,7.00E-176,Q99755,Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha),Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha),GO:0016308; GO:0005524; GO:0031532; GO:0032863; GO:0060326; GO:0005829; GO:0010761; GO:0048041; GO:0030216; GO:0019900; GO:0030027; GO:0016607; GO:0006909; GO:0006661; GO:0072661; GO:0097178; GO:0032587; GO:0007165; GO:0044281,1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; actin cytoskeleton reorganization; activation of Rac GTPase activity; cell chemotaxis; cytosol; fibroblast migration; focal adhesion assembly; keratinocyte differentiation; kinase binding; lamellipodium; nuclear speck; phagocytosis; phosphatidylinositol biosynthetic process; protein targeting to plasma membrane; ruffle assembly; ruffle membrane; signal transduction; small molecule metabolic process,PF01504;,,,,,,,,,PI51A_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; activation of GTPase activity [GO:0090630]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; fibroblast migration [GO:0010761]; focal adhesion assembly [GO:0048041]; glycerophospholipid metabolic process [GO:0006650]; keratinocyte differentiation [GO:0030216]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid biosynthetic process [GO:0008654]; protein targeting to plasma membrane [GO:0072661]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; ruffle assembly [GO:0097178]; signal transduction [GO:0007165] comp141807_c0_seq5,1594,43.4755,0.67298469,0,0,,1.00E-177,Q5I6B8,Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma),Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma),GO:0016308; GO:0005524; GO:0007155; GO:0006935; GO:0005737; GO:0012505; GO:0006887; GO:0005925; GO:0001891; GO:0006909; GO:0046854; GO:0032587; GO:0001931,1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; cell adhesion; chemotaxis; cytoplasm; endomembrane system; exocytosis; focal adhesion; phagocytic cup; phagocytosis; phosphatidylinositol phosphorylation; ruffle membrane; uropod,PF01504;,3.00E-132,CHOYP_LOC663424.1.2,,,,,,,PI51C_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; phagocytosis [GO:0006909] comp141808_c2_seq1,3833,40.2818,0.516642,0,0,,0,Q29466,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_VPP1.1.2,,,,,,,VPP1_BOVIN,Bos taurus (Bovine),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq2,3845,40.2861,0.51494737,0,0,,0,A1A5G6,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,,,,,,,,,VPP1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq3,3819,40.2985,0.51816111,5,30,,0,Q29466,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_VPP1.1.2,,,,,,,VPP1_BOVIN,Bos taurus (Bovine),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq4,3872,40.3151,0.51697189,0,0,,4.00E-174,P32563,"V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)","V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)",GO:0015991; GO:0016049; GO:0000329; GO:0016021; GO:0006797; GO:0006461; GO:0046961; GO:0007035; GO:0000220,"ATP hydrolysis coupled proton transport; cell growth; fungal-type vacuole membrane; integral to membrane; polyphosphate metabolic process; protein complex assembly; proton-transporting ATPase activity, rotational mechanism; vacuolar acidification; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_VPP1.2.2,,,,,,,VPH1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; cell growth [GO:0016049]; polyphosphate metabolic process [GO:0006797]; protein complex assembly [GO:0006461]; proton transport [GO:0015992]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq5,3793,40.3375,0.52060324,0,34,,0,Q9Z1G4,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0005737; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasm; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,1.00E-27,CHOYP_LOC727630.1.1,,,,,,,VPP1_MOUSE,Mus musculus (Mouse),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; regulation of macroautophagy [GO:0016241]; toxin transport [GO:1901998]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq6,2324,43.1583,0.49286066,0,12,,0,Q29466,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_VPP1.1.2,,,,,,,VPP1_BOVIN,Bos taurus (Bovine),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq7,3708,40.6688,0.51758215,0,0,,0,A1A5G6,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,,,,,,,,,VPP1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq8,3696,40.6656,0.51931547,0,0,,0,P25286,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_VPP1.2.2,2.00E-41,ruditapes_c28582,,,,,VPP1_RAT,Rattus norvegicus (Rat),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141808_c2_seq9,3735,40.6961,0.51961151,0,0,,0,Q29466,V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1),GO:0015991; GO:0030659; GO:0015078; GO:0016021; GO:0042470; GO:0000220,"ATP hydrolysis coupled proton transport; cytoplasmic vesicle membrane; hydrogen ion transmembrane transporter activity; integral to membrane; melanosome; vacuolar proton-transporting V-type ATPase, V0 domain",PF01496;,0,CHOYP_VPP1.1.2,,,,,,,VPP1_BOVIN,Bos taurus (Bovine),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] comp141810_c2_seq2,2526,40.9739,0.45571568,0,0,,1.00E-101,Q175F8,Putative oxidoreductase GLYR1 homolog (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60 homolog),Putative oxidoreductase GLYR1 homolog (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60 homolog),GO:0008442; GO:0050662; GO:0006098; GO:0004616; GO:0006573,3-hydroxyisobutyrate dehydrogenase activity; coenzyme binding; pentose-phosphate shunt; phosphogluconate dehydrogenase (decarboxylating) activity; valine metabolic process,PF14833;PF03446;PF00855;,,,,,,,,,GLYR1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp141810_c2_seq3,2598,41.0701,0.46801388,0,0,,8.00E-84,Q29NG1,Putative oxidoreductase GLYR1 homolog (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60 homolog),Putative oxidoreductase GLYR1 homolog (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60 homolog),GO:0050662; GO:0006098; GO:0004616,coenzyme binding; pentose-phosphate shunt; phosphogluconate dehydrogenase (decarboxylating) activity,PF14833;PF03446;PF00855;,4.00E-127,CHOYP_LOC100877728.1.1,,,,,,,GLYR1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp141810_c2_seq7,802,42.6434,0.43944385,0,0,,,,,,,,,6.00E-18,CHOYP_LOC100877728.1.1,,,,,,,,, comp141811_c5_seq1,3331,35.1246,0.92707094,326,2594,,9.00E-09,Q80Y86,Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7),Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7),GO:0005524; GO:0004707; GO:0008156; GO:0000122; GO:0005634; GO:0045732; GO:0001934; GO:0031398; GO:0046777; GO:0032355,ATP binding; MAP kinase activity; negative regulation of DNA replication; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of protein catabolic process; positive regulation of protein phosphorylation; positive regulation of protein ubiquitination; protein autophosphorylation; response to estradiol stimulus,PF00069;,,,,,,,,,MK15_MOUSE,Mus musculus (Mouse),negative regulation of DNA replication [GO:0008156]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; response to estradiol [GO:0032355] comp141811_c5_seq2,3015,35.1907,0.97824362,259,736,,2.00E-112,Q92519,Tribbles homolog 2 (TRB-2),Tribbles homolog 2 (TRB-2),GO:0005737; GO:0005856; GO:0045599; GO:0045081; GO:0006469; GO:0005634; GO:0032436; GO:0004860; GO:0043405; GO:0008134; GO:0016772; GO:0031625; GO:0055106,"cytoplasm; cytoskeleton; negative regulation of fat cell differentiation; negative regulation of interleukin-10 biosynthetic process; negative regulation of protein kinase activity; nucleus; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein kinase inhibitor activity; regulation of MAP kinase activity; transcription factor binding; transferase activity, transferring phosphorus-containing groups; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity",PF00069;,4.00E-65,CHOYP_TRIB2.1.1,6.00E-16,ruditapes_c26290,,,,,TRIB2_HUMAN,Homo sapiens (Human),negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-10 biosynthetic process [GO:0045081]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of MAP kinase activity [GO:0043405] comp141812_c3_seq8,2009,37.0333,0.33093113,311,1546,,1.00E-120,Q91YU8,Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog),Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog),GO:0005730; GO:0001560,nucleolus; regulation of cell growth by extracellular stimulus,PF04427;,1.00E-76,CHOYP_PPAN-B.1.1,,,,,,,SSF1_MOUSE,Mus musculus (Mouse),regulation of cell growth by extracellular stimulus [GO:0001560]; ribosomal large subunit assembly [GO:0000027] comp141814_c0_seq2,2284,33.0998,0.54470381,327,2136,,7.00E-68,Q5RCG9,Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1),Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1),GO:0005634; GO:0016272; GO:0006457,nucleus; prefoldin complex; protein folding,PF02996;,5.00E-88,CHOYP_PFD3.1.1,,,,,,,PFD3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein folding [GO:0006457] comp141817_c0_seq2,2621,38.802,1.03172058,135,543,,2.00E-12,D2GXS7,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_AILME,Ailuropoda melanoleuca (Giant panda),regulation of neuron apoptotic process [GO:0043523] comp141819_c0_seq1,1424,36.868,0.3813221,285,789,,4.00E-90,Q9JJ80,Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog),Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog),GO:0005730,nucleolus,PF04427;,2.00E-72,CHOYP_RPF2.2.2,,,,,,,RPF2_MOUSE,Mus musculus (Mouse),"maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit assembly [GO:0000027]" comp141820_c0_seq2,2999,39.7132,0.51821107,6,21,,6.00E-18,Q13772,Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1),Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1),GO:0050681; GO:0030521; GO:0008584; GO:0005634; GO:0045893; GO:0009725; GO:0003713; GO:0006351,"androgen receptor binding; androgen receptor signaling pathway; male gonad development; nucleus; positive regulation of transcription, DNA-dependent; response to hormone stimulus; transcription coactivator activity; transcription, DNA-dependent",PF12489;,,,,,,,,,NCOA4_HUMAN,Homo sapiens (Human),"androgen receptor signaling pathway [GO:0030521]; male gonad development [GO:0008584]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp141826_c1_seq1,638,42.3197,0.88750218,1,134,,3.00E-19,Q6RY07,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,,,,,,,,,CHIA_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp141826_c1_seq2,2575,36.5437,0.90906143,0,29,,3.00E-16,Q9D7Q1,Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1),GO:0008061; GO:0006032; GO:0008843; GO:0005615; GO:0005764; GO:0000272,chitin binding; chitin catabolic process; endochitinase activity; extracellular space; lysosome; polysaccharide catabolic process,PF01607;PF00704;,,,,,,,,,CHIT1_MOUSE,Mus musculus (Mouse),chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] comp141826_c1_seq4,2574,36.6356,0.90443654,0,0,,8.00E-13,Q28542,Oviduct-specific glycoprotein (Estrogen-dependent oviduct protein) (Estrus-associated oviductal glycoprotein) (OEGP) (Oviductal glycoprotein) (Oviductin),Oviduct-specific glycoprotein (Estrogen-dependent oviduct protein) (Estrus-associated oviductal glycoprotein) (OEGP) (Oviductal glycoprotein) (Oviductin),GO:0005975; GO:0006032; GO:0004568; GO:0007338; GO:0030133,carbohydrate metabolic process; chitin catabolic process; chitinase activity; single fertilization; transport vesicle,PF00704;,,,,,,,,,OVGP1_SHEEP,Ovis aries (Sheep),carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; single fertilization [GO:0007338] comp141827_c0_seq1,2131,37.2126,0.62383784,496,177,,6.00E-155,Q26619,cAMP-dependent protein kinase type II regulatory subunit,cAMP-dependent protein kinase type II regulatory subunit,GO:0030552; GO:0005952; GO:0008603,cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity,PF00027;PF02197;,7.00E-117,CHOYP_BRAFLDRAFT_208819.1.1,,,,,,,KAPR_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp141828_c0_seq1,232,50,0.58342242,3,5,,7.00E-29,Q8R4C0,Calpain-5 (EC 3.4.22.-),Calpain-5 (EC 3.4.22.-),GO:0004198; GO:0009986; GO:0060014; GO:0005622; GO:0001553; GO:0001541; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; cell surface; granulosa cell differentiation; intracellular; luteinization; ovarian follicle development; proteolysis,PF01067;PF00648;,6.00E-24,CHOYP_CAN5.1.1,,,,,,,CAN5_RAT,Rattus norvegicus (Rat),granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508] comp141828_c1_seq1,3085,42.2042,0.51833405,13,7,,1.00E-78,Q9P243,Zinc finger protein ZFAT (Zinc finger gene in AITD susceptibility region) (Zinc finger protein 406),Zinc finger protein ZFAT (Zinc finger gene in AITD susceptibility region) (Zinc finger protein 406),GO:0003677; GO:0001077; GO:0005829; GO:0002244; GO:0046872; GO:0005634; GO:0060712,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cytosol; hematopoietic progenitor cell differentiation; metal ion binding; nucleus; spongiotrophoblast layer development,,3.00E-80,CHOYP_ZFAT.1.1,,,,,,,ZFAT_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244]; multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spongiotrophoblast layer development [GO:0060712] comp141828_c1_seq2,4202,42.8367,0.49521942,119,126,,8.00E-27,P18722,Gastrula zinc finger protein XlCGF46.1 (Fragment),Gastrula zinc finger protein XlCGF46.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG46_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141830_c0_seq3,1110,35.4955,0.46436819,60,526,,9.00E-43,Q9GLW9,"Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Peroxiredoxin V) (Prx-V) (Thioredoxin reductase)","Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Peroxiredoxin V) (Prx-V) (Thioredoxin reductase)",GO:0005739; GO:0004601; GO:0051920; GO:0005777,mitochondrion; peroxidase activity; peroxiredoxin activity; peroxisome,PF08534;,1.00E-35,CHOYP_LOC101075536.1.1,,,,,,,PRDX5_PAPHA,Papio hamadryas (Hamadryas baboon), comp141831_c0_seq1,1735,37.5216,0.39942492,160,0,,1.00E-153,Q9UW86,Serine/threonine-protein phosphatase PP1 (EC 3.1.3.16),Serine/threonine-protein phosphatase PP1 (EC 3.1.3.16) (Phosphoprotein phosphatase 1),GO:0000077; GO:0000076; GO:0030437; GO:0007114; GO:0005935; GO:0006873; GO:0007059; GO:0000778; GO:0005977; GO:0016576; GO:0005847; GO:0001400; GO:0007126; GO:0046872; GO:0007094; GO:0005730; GO:0034501; GO:0000164; GO:0004722; GO:0006364; GO:0006109; GO:0000903; GO:0031297; GO:0009408; GO:0005816; GO:0030847; GO:0030846,"DNA damage checkpoint; DNA replication checkpoint; ascospore formation; cell budding; cellular bud neck; cellular ion homeostasis; chromosome segregation; condensed nuclear chromosome kinetochore; glycogen metabolic process; histone dephosphorylation; mRNA cleavage and polyadenylation specificity factor complex; mating projection base; meiosis; metal ion binding; mitotic spindle assembly checkpoint; nucleolus; protein localization to kinetochore; protein phosphatase type 1 complex; protein serine/threonine phosphatase activity; rRNA processing; regulation of carbohydrate metabolic process; regulation of cell shape during vegetative growth phase; replication fork processing; response to heat; spindle pole body; termination of RNA polymerase II transcription, exosome-dependent; termination of RNA polymerase II transcription, poly(A)-coupled",PF00149;PF16891;,,,,,,,,,PP1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of chromosome condensation [GO:1902340] comp141831_c0_seq2,1167,40.3599,0.42441892,31,0,,9.00E-153,O82733,Serine/threonine-protein phosphatase PP1 isozyme 7 (EC 3.1.3.16),Serine/threonine-protein phosphatase PP1 isozyme 7 (EC 3.1.3.16),GO:0046872; GO:0004721,metal ion binding; phosphoprotein phosphatase activity,PF00149;PF16891;,3.00E-118,CHOYP_LOC100378725.1.1,,,,,,,PP17_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp141832_c1_seq1,1641,35.1615,0.47918306,58,91,,7.00E-33,Q9D0U9,Protein ARV1,Protein ARV1,GO:0008206; GO:0030301; GO:0016021; GO:0090181; GO:0006665,bile acid metabolic process; cholesterol transport; integral to membrane; regulation of cholesterol metabolic process; sphingolipid metabolic process,PF04161;,,,,,,,,,ARV1_MOUSE,Mus musculus (Mouse),bile acid metabolic process [GO:0008206]; cholesterol transport [GO:0030301]; intracellular sterol transport [GO:0032366]; regulation of cholesterol metabolic process [GO:0090181]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665] comp141832_c1_seq2,1438,35.605,0.44337653,27,135,,2.00E-12,Q9HDX5,Protein arv1,Protein arv1,GO:0000139; GO:0006696; GO:0030176; GO:0032366; GO:0006665,Golgi membrane; ergosterol biosynthetic process; integral to endoplasmic reticulum membrane; intracellular sterol transport; sphingolipid metabolic process,PF04161;,,,,,,,,,ARV1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ergosterol biosynthetic process [GO:0006696]; intracellular sterol transport [GO:0032366]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665]; sterol metabolic process [GO:0016125] comp141832_c1_seq4,2063,33.3495,0.50849975,5,45,,3.00E-32,Q9D0U9,Protein ARV1,Protein ARV1,GO:0008206; GO:0030301; GO:0016021; GO:0090181; GO:0006665,bile acid metabolic process; cholesterol transport; integral to membrane; regulation of cholesterol metabolic process; sphingolipid metabolic process,PF04161;,,,,,,,,,ARV1_MOUSE,Mus musculus (Mouse),bile acid metabolic process [GO:0008206]; cholesterol transport [GO:0030301]; intracellular sterol transport [GO:0032366]; regulation of cholesterol metabolic process [GO:0090181]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665] comp141832_c1_seq8,924,38.8528,0.55957147,2,13,,3.00E-16,Q54GD9,Protein arv1 homolog,Protein arv1 homolog,GO:0000139; GO:0005789; GO:0016021; GO:0006869; GO:0006665,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; lipid transport; sphingolipid metabolic process,PF04161;,,,,,,,,,ARV1_DICDI,Dictyostelium discoideum (Slime mold),intracellular sterol transport [GO:0032366]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665]; sterol metabolic process [GO:0016125] comp141833_c0_seq4,1396,36.8195,0.46092595,27,262,,6.00E-09,Q04202,Transposable element Tcb2 transposase,Transposable element Tcb2 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,2.00E-27,CHOYP_TC1A.2.2,,,,,,,TCB2_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141833_c0_seq8,1231,36.7994,0.42463837,46,106,,2.00E-11,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,3.00E-17,CHOYP_LOC100202983.1.2,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141835_c2_seq1,1915,42.0888,0.62086474,26,39,,2.00E-21,Q91VJ5,Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1),Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1),GO:0010494; GO:0071598; GO:0005634; GO:0006355; GO:0034063; GO:0006351,"cytoplasmic stress granule; neuronal ribonucleoprotein granule; nucleus; regulation of transcription, DNA-dependent; stress granule assembly; transcription, DNA-dependent",PF00397;,4.00E-12,CHOYP_TSP_00320.1.1,,,,,,,PQBP1_MOUSE,Mus musculus (Mouse),"alternative mRNA splicing, via spliceosome [GO:0000380]; cilium morphogenesis [GO:0060271]; neuron projection development [GO:0031175]; regulation of dendrite morphogenesis [GO:0048814]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]" comp141835_c2_seq9,2405,42.2869,0.51277589,0,0,,4.00E-21,Q91VJ5,Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1),Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1),GO:0010494; GO:0071598; GO:0005634; GO:0006355; GO:0034063; GO:0006351,"cytoplasmic stress granule; neuronal ribonucleoprotein granule; nucleus; regulation of transcription, DNA-dependent; stress granule assembly; transcription, DNA-dependent",PF00397;,5.00E-12,CHOYP_TSP_00320.1.1,,,,,,,PQBP1_MOUSE,Mus musculus (Mouse),"alternative mRNA splicing, via spliceosome [GO:0000380]; cilium morphogenesis [GO:0060271]; neuron projection development [GO:0031175]; regulation of dendrite morphogenesis [GO:0048814]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]" comp141836_c0_seq1,4104,40.8382,0.43510834,280,44,,7.00E-17,Q6PFQ7,Ras GTPase-activating protein 4 (Calcium-promoted Ras inactivator) (Ras p21 protein activator 4) (RasGAP-activating-like protein 2),Ras GTPase-activating protein 4 (Calcium-promoted Ras inactivator) (Ras p21 protein activator 4) (RasGAP-activating-like protein 2),GO:0005099; GO:0005737; GO:0005829; GO:0035556; GO:0031235; GO:0046872; GO:0046580; GO:0005543,Ras GTPase activator activity; cytoplasm; cytosol; intracellular signal transduction; intrinsic to internal side of plasma membrane; metal ion binding; negative regulation of Ras protein signal transduction; phospholipid binding,PF00779;PF00168;PF00169;PF00616;,2.00E-25,CHOYP_PHUM_PHUM335410.1.1,,,,,,,RASL2_MOUSE,Mus musculus (Mouse),cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; negative regulation of Ras protein signal transduction [GO:0046580] comp141836_c0_seq2,3013,41.7524,0.47520095,47,8,,1.00E-16,Q8L706,Synaptotagmin-5 (NTMC2T2.1) (Synaptotagmin E),Synaptotagmin-5 (NTMC2T2.1) (Synaptotagmin E),GO:0012505; GO:0005783; GO:0016021; GO:0008289; GO:0046872; GO:0005886; GO:0009506,endomembrane system; endoplasmic reticulum; integral to membrane; lipid binding; metal ion binding; plasma membrane; plasmodesma,PF00168;PF17047;,2.00E-25,CHOYP_PHUM_PHUM335410.1.1,,,,,,,SYT5_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp141839_c0_seq1,3123,43.5159,0.47470613,35,257,,1.00E-09,Q3UKJ7,"WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]","WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]",GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,6.00E-107,CHOYP_BRAFLDRAFT_276592.1.1,,,,,,,SMU1_MOUSE,Mus musculus (Mouse), comp141839_c0_seq2,3106,43.4965,0.47774385,6,99,,0,Q8NI36,WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP),WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP),GO:0005730; GO:0006364; GO:0030516; GO:0050896; GO:0001895; GO:0032040; GO:0007601,nucleolus; rRNA processing; regulation of axon extension; response to stimulus; retina homeostasis; small-subunit processome; visual perception,PF12894;PF04192;PF00400;,6.00E-107,CHOYP_BRAFLDRAFT_276592.1.1,,,,,,,WDR36_HUMAN,Homo sapiens (Human),regulation of axon extension [GO:0030516]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; rRNA processing [GO:0006364]; visual perception [GO:0007601] comp141841_c0_seq1,2429,38.7814,0.48564688,117,1127,,5.00E-179,O57478,"Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)","Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)",GO:0051537; GO:0004325; GO:0006783; GO:0046872; GO:0005743,"2 iron, 2 sulfur cluster binding; ferrochelatase activity; heme biosynthetic process; metal ion binding; mitochondrial inner membrane",PF00762;,,,,,,,,,HEMH_XENLA,Xenopus laevis (African clawed frog),heme biosynthetic process [GO:0006783] comp141841_c0_seq2,2284,39.5797,0.49639587,26,172,,1.00E-179,O57478,"Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)","Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)",GO:0051537; GO:0004325; GO:0006783; GO:0046872; GO:0005743,"2 iron, 2 sulfur cluster binding; ferrochelatase activity; heme biosynthetic process; metal ion binding; mitochondrial inner membrane",PF00762;,2.00E-87,CHOYP_LOC100692139.1.1,,,,,,,HEMH_XENLA,Xenopus laevis (African clawed frog),heme biosynthetic process [GO:0006783] comp141844_c0_seq1,2999,37.2457,0.9823373,22,87,,3.00E-14,Q1RNF8,Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s),Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s),GO:0042731; GO:0032093; GO:0000122; GO:0005634; GO:0043621,PH domain binding; SAM domain binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein self-association,PF00536;,,,,,,,,,SAM11_MOUSE,Mus musculus (Mouse),negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp141844_c0_seq2,2981,37.2694,0.98716737,9,98,,3.00E-14,Q1RNF8,Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s),Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s),GO:0042731; GO:0032093; GO:0000122; GO:0005634; GO:0043621,PH domain binding; SAM domain binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein self-association,PF00536;,,,,,,,,,SAM11_MOUSE,Mus musculus (Mouse),negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp141844_c0_seq3,479,41.9624,1.1895373,1,4,,3.00E-12,O88450,Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin),Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin),GO:0003677; GO:0048706; GO:0005576; GO:0046872; GO:0001843; GO:0005634; GO:0045944; GO:0033599; GO:0006351,"DNA binding; embryonic skeletal system development; extracellular region; metal ion binding; neural tube closure; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of mammary gland epithelial cell proliferation; transcription, DNA-dependent",PF01342;PF01753;,,,,,,,,,DEAF1_RAT,Rattus norvegicus (Rat),"embryonic skeletal system development [GO:0048706]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of multicellular organismal development [GO:2000026]; transcription, DNA-templated [GO:0006351]" comp141846_c1_seq1,2565,36.9981,0.33692842,174,607,,6.00E-55,Q7ZWE3,La-related protein 7 (La ribonucleoprotein domain family member 7),La-related protein 7 (La ribonucleoprotein domain family member 7),GO:0003723; GO:0006396; GO:0000166; GO:0005634; GO:0030529,RNA binding; RNA processing; nucleotide binding; nucleus; ribonucleoprotein complex,PF05383;PF00076;PF08777;,,,,,,,,,LARP7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),RNA processing [GO:0006396] comp141846_c1_seq2,2271,37.4725,0.32392364,29,157,,4.00E-55,Q28G87,La-related protein 7 (La ribonucleoprotein domain family member 7),La-related protein 7 (La ribonucleoprotein domain family member 7),GO:0003723; GO:0006396; GO:0000166; GO:0005634; GO:0030529,RNA binding; RNA processing; nucleotide binding; nucleus; ribonucleoprotein complex,PF05383;PF00076;PF08777;,,,2.00E-15,ruditapes_c10931,,,,,LARP7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),RNA processing [GO:0006396] comp141847_c0_seq1,1579,41.7353,0.6993861,30,304,,,,,,,,,4.00E-68,CHOYP_LOC100367548.1.1,,,,,,,,, comp141847_c0_seq2,1462,41.4501,0.7026517,36,273,,1.00E-99,Q9DC33,High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1) (Inhibitor of BRAF35) (iBRAF),High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1) (Inhibitor of BRAF35) (iBRAF),GO:0003677; GO:0016568; GO:0045665; GO:0000122; GO:0005634; GO:0006351,"DNA binding; chromatin modification; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF00505;,2.00E-65,CHOYP_LOC100367548.1.1,,,,,,,HM20A_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp141850_c0_seq2,1258,45.0715,0.7936613,2,383,,3.00E-64,Q09621,Beta-lactamase domain-containing protein 2,Beta-lactamase domain-containing protein 2,GO:0016021,integral to membrane,PF00144;,,,1.00E-14,ruditapes_c9191,,,,,LACT2_CAEEL,Caenorhabditis elegans, comp141852_c0_seq1,1900,43.5789,0.79936014,434,4118,,5.00E-08,Q923L3,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_MOUSE,Mus musculus (Mouse),glucose homeostasis [GO:0042593]; startle response [GO:0001964] comp141853_c0_seq1,2277,41.7216,0.3231765,561,6340,,2.00E-152,Q5ZLS8,Integrator complex subunit 10 (Int10),Integrator complex subunit 10 (Int10),GO:0005737; GO:0032039; GO:0016180,cytoplasm; integrator complex; snRNA processing,,3.00E-40,CHOYP_BRAFLDRAFT_203057.1.1,,,,,,,INT10_CHICK,Gallus gallus (Chicken),snRNA processing [GO:0016180] comp141855_c0_seq1,1578,36.8821,0.49321836,606,5462,,3.00E-74,O35586,Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1),Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1),GO:0006695; GO:0050992; GO:0016787; GO:0004452; GO:0008299; GO:0046872; GO:0005777,cholesterol biosynthetic process; dimethylallyl diphosphate biosynthetic process; hydrolase activity; isopentenyl-diphosphate delta-isomerase activity; isoprenoid biosynthetic process; metal ion binding; peroxisome,PF00293;,2.00E-64,CHOYP_APC11.1.1,,,,,,,IDI1_MESAU,Mesocricetus auratus (Golden hamster),cholesterol biosynthetic process [GO:0006695]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isoprenoid biosynthetic process [GO:0008299] comp141856_c2_seq1,1973,47.998,0.43834473,234,0,male,5.00E-92,Q86WZ0,HEAT repeat-containing protein 4,HEAT repeat-containing protein 4,,,PF02985;,,,,,,,,,HEAT4_HUMAN,Homo sapiens (Human), comp141856_c2_seq2,1805,49.0859,0.45054976,95,0,,,,,,,,,1.00E-156,CHOYP_LOC100369763.1.1,,,,,,,,, comp141856_c3_seq1,1789,43.4321,0.44070495,672,0,,2.00E-08,Q86WZ0,HEAT repeat-containing protein 4,HEAT repeat-containing protein 4,,,PF02985;,,,,,,,,,HEAT4_HUMAN,Homo sapiens (Human), comp141857_c1_seq1,2431,41.9169,0.32879088,5,15,,3.00E-35,Q2T9U5,Putative RNA exonuclease NEF-sp (EC 3.1.-.-),Putative RNA exonuclease NEF-sp (EC 3.1.-.-),GO:0003723; GO:0004527; GO:0090305; GO:0000166,RNA binding; exonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleotide binding,PF00929;PF00076;,2.00E-37,CHOYP_LOC660590.1.1,,,,,,,REXON_BOVIN,Bos taurus (Bovine), comp141857_c1_seq2,2702,41.1547,0.36878253,17,64,,,,,,,,,2.00E-37,CHOYP_LOC660590.1.1,,,,,,,,, comp141858_c0_seq1,1691,47.1319,0.39293008,182,208,,1.00E-77,Q8NDG6,Putative ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9),Putative ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9),GO:0005524; GO:0008026; GO:0043046; GO:0030154; GO:0009566; GO:0031047; GO:0007140; GO:0007275; GO:0003676; GO:0005634; GO:0071547; GO:0034587; GO:0007283,ATP binding; ATP-dependent helicase activity; DNA methylation involved in gamete generation; cell differentiation; fertilization; gene silencing by RNA; male meiosis; multicellular organismal development; nucleic acid binding; nucleus; piP-body; piRNA metabolic process; spermatogenesis,PF00270;PF04408;PF00271;PF00567;,,,,,,,,,TDRD9_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283] comp141858_c1_seq2,1972,41.8357,0.37715661,191,328,,4.00E-57,Q5EAR5,tRNA 2'-phosphotransferase 1 (EC 2.7.1.160),tRNA 2'-phosphotransferase 1 (EC 2.7.1.160),GO:0000215; GO:0006388,"tRNA 2'-phosphotransferase activity; tRNA splicing, via endonucleolytic cleavage and ligation",PF01885;,,,5.00E-53,ruditapes_c12968,,,,,TRPT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp141858_c3_seq1,1573,45.5181,0.3949225,96,85,,2.00E-164,Q3MHU3,Putative ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9),Putative ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9),GO:0005524; GO:0008026; GO:0043046; GO:0030154; GO:0009566; GO:0031047; GO:0007140; GO:0007275; GO:0003676; GO:0005634; GO:0071547; GO:0034587; GO:0007283,ATP binding; ATP-dependent helicase activity; DNA methylation involved in gamete generation; cell differentiation; fertilization; gene silencing by RNA; male meiosis; multicellular organismal development; nucleic acid binding; nucleus; piP-body; piRNA metabolic process; spermatogenesis,PF00270;PF04408;PF00271;PF00567;,5.00E-143,CHOYP_LOC100891933.1.1,,,,,,,TDRD9_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283] comp141859_c0_seq1,4206,34.9501,0.59951438,25,4,,,,,,,,,0,CHOYP_LOC100367739.1.1,,,,,,,,, comp141859_c0_seq2,4174,34.9066,0.59796392,154,3,,9.00E-106,Q9UL16,"Coiled-coil domain-containing protein 19, mitochondrial (Nasopharyngeal epithelium-specific protein 1)",Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1),GO:0005739; GO:0005634,mitochondrion; nucleus,,0,CHOYP_THOC2.1.2,5.00E-63,ruditapes2_c345,,,,,CCD19_HUMAN,Homo sapiens (Human), comp141859_c0_seq3,4193,34.9392,0.6172174,117,11,,,,,,,,,0,CHOYP_LOC100367739.1.1,,,,,,,,, comp141859_c0_seq4,4227,34.8947,0.61360136,146,12,,1.00E-105,Q9UL16,"Coiled-coil domain-containing protein 19, mitochondrial (Nasopharyngeal epithelium-specific protein 1)",Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1),GO:0005739; GO:0005634,mitochondrion; nucleus,,,,,,,,,,CCD19_HUMAN,Homo sapiens (Human), comp141860_c2_seq1,306,37.2549,0.56712428,16,54,,,,,,,,,,,2.00E-17,ruditapes_c17260,,,,,,, comp141861_c1_seq1,1449,42.7881,0.50172508,299,697,,0,P60892,Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I) (PRS-I),Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I) (PRS-I),GO:0006015; GO:0043531; GO:0016208; GO:0006167; GO:0005524; GO:0019003; GO:0030246; GO:0016301; GO:0000287; GO:0031100; GO:0042803; GO:0004749; GO:0002189,5-phosphoribose 1-diphosphate biosynthetic process; ADP binding; AMP binding; AMP biosynthetic process; ATP binding; GDP binding; carbohydrate binding; kinase activity; magnesium ion binding; organ regeneration; protein homodimerization activity; ribose phosphate diphosphokinase activity; ribose phosphate diphosphokinase complex,PF14572;PF13793;,0,CHOYP_PRPS1.1.1,,,5.00E-152,AM857246.p.cg.6,9,,PRPS1_RAT,Rattus norvegicus (Rat),5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; AMP biosynthetic process [GO:0006167]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleotide biosynthetic process [GO:0009165]; organ regeneration [GO:0031100]; ribose phosphate metabolic process [GO:0019693]; urate biosynthetic process [GO:0034418] comp141863_c0_seq1,1715,37.8426,1.15736716,7,322,,1.00E-22,Q7T3S3,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST-1) (C4ST1) (zC4ST-1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST-1) (C4ST1) (zC4ST-1),GO:0000139; GO:0016051; GO:0047756; GO:0030206; GO:0016021; GO:0008045; GO:0007517,Golgi membrane; carbohydrate biosynthetic process; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; integral to membrane; motor neuron axon guidance; muscle organ development,PF03567;,,,,,,,,,CHSTB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517] comp141863_c0_seq2,1778,37.7953,1.1976406,1,440,female>male,4.00E-15,Q6AXM1,Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST),Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST),GO:0000139; GO:0016051; GO:0016021; GO:0008146,Golgi membrane; carbohydrate biosynthetic process; integral to membrane; sulfotransferase activity,PF03567;,,,,,,,,,CHSTA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate biosynthetic process [GO:0016051] comp141864_c0_seq12,1293,32.4826,0.41087775,0,0,,2.00E-06,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141864_c0_seq16,1250,32.88,0.35548211,0,0,,2.00E-06,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141864_c0_seq2,1304,32.6687,0.40270699,0,0,,3.00E-06,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141865_c0_seq1,1199,40.4504,0.37680579,193,812,,5.00E-75,Q5ZIM6,Protein AATF (Apoptosis-antagonizing transcription factor),Protein AATF (Apoptosis-antagonizing transcription factor),GO:0007155; GO:0005813; GO:0005737; GO:0040016; GO:0005925; GO:0042985; GO:0043066; GO:0032929; GO:0005730; GO:0045944; GO:0007346; GO:0006974; GO:0042254,cell adhesion; centrosome; cytoplasm; embryonic cleavage; focal adhesion; negative regulation of amyloid precursor protein biosynthetic process; negative regulation of apoptotic process; negative regulation of superoxide anion generation; nucleolus; positive regulation of transcription from RNA polymerase II promoter; regulation of mitotic cell cycle; response to DNA damage stimulus; ribosome biogenesis,PF13339;PF08164;,2.00E-20,CHOYP_AATF.1.1,,,,,,,AATF_CHICK,Gallus gallus (Chicken),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp141866_c0_seq1,2999,36.012,0.24021392,3350,1006,,0,Q16960,"Dynein intermediate chain 3, ciliary","Dynein intermediate chain 3, ciliary",GO:0035085; GO:0030286; GO:0005874; GO:0003774,cilium axoneme; dynein complex; microtubule; motor activity,,0,CHOYP_LOC100378071.1.1,,,,,,,DYI3_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina), comp141867_c1_seq1,3597,41.3122,0.49816277,0,0,,4.00E-177,Q8R3Q2,Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2),Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2),GO:0005737; GO:0019903; GO:0043666,cytoplasm; protein phosphatase binding; regulation of phosphoprotein phosphatase activity,PF04499;,,,,,,,,,PP6R2_MOUSE,Mus musculus (Mouse),regulation of phosphoprotein phosphatase activity [GO:0043666] comp141867_c1_seq2,2062,39.4277,0.55132968,14,0,,2.00E-14,P40856,SIT4-associating protein SAP185,SIT4-associating protein SAP185,GO:0000082; GO:0005737; GO:0002098,G1/S transition of mitotic cell cycle; cytoplasm; tRNA wobble uridine modification,PF04499;,2.00E-155,CHOYP_PP6R3.1.1,,,,,,,SA185_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),G1/S transition of mitotic cell cycle [GO:0000082]; tRNA wobble uridine modification [GO:0002098] comp141867_c1_seq3,3192,40.9461,0.48795086,0,0,,0,Q5F471,Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3),Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3),,,PF04499;,,,,,,,,,PP6R3_CHICK,Gallus gallus (Chicken),regulation of phosphoprotein phosphatase activity [GO:0043666] comp141867_c1_seq4,3174,40.9263,0.49131763,0,0,,0,Q6NRI0,Serine/threonine-protein phosphatase 6 regulatory subunit 3-A (SAPS domain family member 3-A),Serine/threonine-protein phosphatase 6 regulatory subunit 3-A (SAPS domain family member 3-A),,,PF04499;,0,CHOYP_PP6R3.1.1,,,,,,,P6R3A_XENLA,Xenopus laevis (African clawed frog), comp141867_c1_seq5,3615,41.3278,0.49517828,0,0,,0,O75170,Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2),Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2),GO:0005737; GO:0043231,cytoplasm; intracellular membrane-bounded organelle,PF04499;,,,,,,,,,PP6R2_HUMAN,Homo sapiens (Human), comp141867_c1_seq7,3537,41.3345,0.48598448,0,0,,0,Q6NRI0,Serine/threonine-protein phosphatase 6 regulatory subunit 3-A (SAPS domain family member 3-A),Serine/threonine-protein phosphatase 6 regulatory subunit 3-A (SAPS domain family member 3-A),,,PF04499;,0,CHOYP_PP6R3.1.1,,,,,,,P6R3A_XENLA,Xenopus laevis (African clawed frog), comp141867_c1_seq8,3555,41.3502,0.48302994,0,0,,0,Q5F471,Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3),Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3),,,PF04499;,,,,,,,,,PP6R3_CHICK,Gallus gallus (Chicken),regulation of phosphoprotein phosphatase activity [GO:0043666] comp141872_c0_seq1,1737,42.1992,0.61064534,234,44,,6.00E-45,Q7L0X2,Protein FAM194A,Glutamate-rich protein 6 (Protein FAM194A),,,PF14977;,7.00E-59,CHOYP_LOC100378540.3.3,,,,,,,F194A_HUMAN,Homo sapiens (Human), comp141872_c0_seq2,2588,43.7017,0.61048276,437,6,,,,,,,,,1.00E-19,CHOYP_LOC764814.1.1,,,,,,,,, comp141872_c0_seq3,2546,43.48,0.60149576,138,15,,3.00E-43,Q7L0X2,Protein FAM194A,Glutamate-rich protein 6 (Protein FAM194A),,,PF14977;,8.00E-54,CHOYP_BRAFLDRAFT_117750.1.1,,,,,,,F194A_HUMAN,Homo sapiens (Human), comp141872_c0_seq4,2783,44.0891,0.62461213,0,0,,,,,,,,,1.00E-57,CHOYP_LOC100378540.3.3,,,,,,,,, comp141872_c0_seq5,2741,44.0715,0.61991737,36,0,,,,,,,,,4.00E-20,CHOYP_LOC764814.1.1,6.00E-35,ruditapes_c23773,,,,,,, comp141873_c1_seq2,3458,38.0567,0.46337845,8,2,,8.00E-08,Q52JK6,Probable NOT transcription complex subunit VIP2 (Protein VIRE2 INTERACTING PROTEIN2) (NbVIP2) (Fragment),Probable NOT transcription complex subunit VIP2 (Protein VIRE2 INTERACTING PROTEIN2) (NbVIP2) (Fragment),GO:0015074; GO:0005634; GO:0006355; GO:0006351,"DNA integration; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04153;,2.00E-108,CHOYP_CNOT3.1.1,4.00E-26,ruditapes_c19232,,,,,VIP2_NICBE,Nicotiana benthamiana,"DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141873_c1_seq3,4234,38.8049,0.47100496,0,0,,5.00E-58,O13870,General negative regulator of transcription subunit 3,General negative regulator of transcription subunit 3,GO:0030015; GO:0005829; GO:0000289; GO:0005634; GO:0006357; GO:0006351,"CCR4-NOT core complex; cytosol; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF04153;PF04065;,,,,,,,,,NOT3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp141873_c1_seq4,4351,39.0255,0.47712943,0,0,,4.00E-101,Q8K0V4,CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3),CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3),GO:0030014; GO:0000932; GO:0031047; GO:0033147; GO:0005634; GO:2000036; GO:0006355; GO:0006417; GO:0006351; GO:0001829,"CCR4-NOT complex; cytoplasmic mRNA processing body; gene silencing by RNA; negative regulation of intracellular estrogen receptor signaling pathway; nucleus; regulation of stem cell maintenance; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent; trophectodermal cell differentiation",PF04153;PF04065;,,,2.00E-105,ruditapes_c18259,,,,,CNOT3_MOUSE,Mus musculus (Mouse),"gene silencing by RNA [GO:0031047]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]" comp141873_c1_seq5,2402,40.383,0.50142455,0,0,,5.00E-61,O75175,CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2),CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2),GO:0030014; GO:0000932; GO:0005829; GO:0031047; GO:0000289; GO:0005634; GO:2000036; GO:0006355; GO:0006417; GO:0006351; GO:0001829,"CCR4-NOT complex; cytoplasmic mRNA processing body; cytosol; gene silencing by RNA; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; regulation of stem cell maintenance; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent; trophectodermal cell differentiation",PF04153;PF04065;,1.00E-108,CHOYP_CNOT3.1.1,,,,,,,CNOT3_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]" comp141874_c0_seq1,1229,43.6127,0.69054616,60,468,,4.00E-110,Q91WI7,Integrin-alpha FG-GAP repeat-containing protein 2,Integrin-alpha FG-GAP repeat-containing protein 2,,,PF15907;,1.00E-40,CHOYP_ITFG2.1.1,,,,,,,ITFG2_MOUSE,Mus musculus (Mouse),germinal center B cell differentiation [GO:0002314] comp141876_c0_seq1,2612,41.0413,0.50202263,21,79,,1.00E-130,Q5F3N6,Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1),Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1),GO:0035517; GO:0003682; GO:0005737; GO:0035522; GO:0071108; GO:0051726; GO:0001558; GO:0004221; GO:0006511; GO:0004843,PR-DUB complex; chromatin binding; cytoplasm; monoubiquitinated histone H2A deubiquitination; protein K48-linked deubiquitination; regulation of cell cycle; regulation of cell growth; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF01088;,1.00E-147,CHOYP_BAP1.1.1,,,,,,,BAP1_CHICK,Gallus gallus (Chicken),monoubiquitinated histone H2A deubiquitination [GO:0035522]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141876_c0_seq2,2476,41.4378,0.45402168,7,51,,7.00E-135,C4A0D9,Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1),Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1),GO:0035517; GO:0003682; GO:0005737; GO:0035522; GO:0071108; GO:0051726; GO:0001558; GO:0004221; GO:0006511; GO:0004843,PR-DUB complex; chromatin binding; cytoplasm; monoubiquitinated histone H2A deubiquitination; protein K48-linked deubiquitination; regulation of cell cycle; regulation of cell growth; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF01088;,8.00E-149,CHOYP_BAP1.1.1,,,,,,,BAP1_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),monoubiquitinated histone H2A deubiquitination [GO:0035522]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; ubiquitin-dependent protein catabolic process [GO:0006511] comp141877_c0_seq3,2638,29.5299,0.34794652,5,18,,1.00E-06,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp141878_c0_seq1,3569,43.3455,0.58410288,49,17,,6.00E-79,Q8NB50,Zinc finger protein 62 homolog (Zfp-62),Zinc finger protein 62 homolog (Zfp-62),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZFP62_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141878_c0_seq2,1910,46.8063,0.66552449,9,9,,2.00E-62,P51522,Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1),Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZNF83_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141878_c0_seq3,1267,47.5138,0.6572025,12,8,,7.00E-47,P10073,Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50),Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSC22_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp141878_c0_seq4,3096,43.0233,0.61953252,27,27,,3.00E-74,Q5R8X1,Zinc finger protein 665,Zinc finger protein 665,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN665_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141879_c0_seq1,5735,42.3191,0.75636014,0,0,,1.00E-141,Q5R8V1,Protein CASP,Protein CASP,GO:0030173; GO:0006891,integral to Golgi membrane; intra-Golgi vesicle-mediated transport,PF08172;,3.00E-171,CHOYP_CUX1.1.2,,,,,,,CASP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intra-Golgi vesicle-mediated transport [GO:0006891] comp141879_c0_seq11,3423,48.0573,0.73393417,0,0,,2.00E-06,Q22812,Homeobox protein ceh-39,Homeobox protein ceh-39,GO:0000794; GO:0043073; GO:0000122; GO:0007538; GO:0043565; GO:0003700,condensed nuclear chromosome; germ cell nucleus; negative regulation of transcription from RNA polymerase II promoter; primary sex determination; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF02376;PF00046;,3.00E-41,CHOYP_MUC1.1.5,,,,,,,HM39_CAEEL,Caenorhabditis elegans,cell differentiation [GO:0030154]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; primary sex determination [GO:0007538]; system development [GO:0048731] comp141879_c0_seq4,3239,38.4378,0.73368044,0,0,,6.00E-56,P10180,Homeobox protein cut,Homeobox protein cut,GO:0061332; GO:0048098; GO:0007417; GO:0070983; GO:0008585; GO:0060288; GO:0008587; GO:0000278; GO:0045746; GO:0000122; GO:0005634; GO:0030713; GO:0007422; GO:0007605; GO:0003700; GO:0035277; GO:0000976; GO:0006351,"Malpighian tubule bud morphogenesis; antennal joint development; central nervous system development; dendrite guidance; female gonad development; formation of a compartment boundary; imaginal disc-derived wing margin morphogenesis; mitotic cell cycle; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; ovarian follicle cell stalk formation; peripheral nervous system development; sensory perception of sound; sequence-specific DNA binding transcription factor activity; spiracle morphogenesis, open tracheal system; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF02376;PF00046;,,,,,,,,,CUT_DROME,Drosophila melanogaster (Fruit fly),"antennal development [GO:0007469]; antennal joint development [GO:0048098]; cell fate commitment [GO:0045165]; central nervous system development [GO:0007417]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; female gonad development [GO:0008585]; formation of a compartment boundary [GO:0060288]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cell cycle [GO:0000278]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ boundary specification [GO:0008052]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of sound [GO:0007605]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription, DNA-templated [GO:0006351]" comp141879_c0_seq5,927,49.9461,0.7000395,0,0,,2.00E-60,P10180,Homeobox protein cut,Homeobox protein cut,GO:0061332; GO:0048098; GO:0007417; GO:0070983; GO:0008585; GO:0060288; GO:0008587; GO:0000278; GO:0045746; GO:0000122; GO:0005634; GO:0030713; GO:0007422; GO:0007605; GO:0003700; GO:0035277; GO:0000976; GO:0006351,"Malpighian tubule bud morphogenesis; antennal joint development; central nervous system development; dendrite guidance; female gonad development; formation of a compartment boundary; imaginal disc-derived wing margin morphogenesis; mitotic cell cycle; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; ovarian follicle cell stalk formation; peripheral nervous system development; sensory perception of sound; sequence-specific DNA binding transcription factor activity; spiracle morphogenesis, open tracheal system; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF02376;PF00046;,,,,,,,,,CUT_DROME,Drosophila melanogaster (Fruit fly),"antennal development [GO:0007469]; antennal joint development [GO:0048098]; cell fate commitment [GO:0045165]; central nervous system development [GO:0007417]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; female gonad development [GO:0008585]; formation of a compartment boundary [GO:0060288]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cell cycle [GO:0000278]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ boundary specification [GO:0008052]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of sound [GO:0007605]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription, DNA-templated [GO:0006351]" comp141879_c0_seq6,831,49.4585,0.67779302,0,0,,3.00E-27,P53565,Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP2) (Homeobox protein cux-1) (Fragment),Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP2) (Homeobox protein cux-1),GO:0000139; GO:0007275; GO:0005634; GO:0000301; GO:0043565; GO:0003700; GO:0006351,"Golgi membrane; multicellular organismal development; nucleus; retrograde transport, vesicle recycling within Golgi; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02376;PF00046;,8.00E-42,CHOYP_MUC1.1.5,,,,,,,CUX1_RAT,Rattus norvegicus (Rat),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; transcription, DNA-templated [GO:0006351]" comp141879_c0_seq7,2445,46.135,0.6313332,234,2443,,0,Q13948,Protein CASP,Protein CASP,GO:0030173; GO:0006891,integral to Golgi membrane; intra-Golgi vesicle-mediated transport,PF08172;,0,CHOYP_LOC100313569.1.1,,,,,,,CASP_HUMAN,Homo sapiens (Human),intra-Golgi vesicle-mediated transport [GO:0006891] comp141879_c0_seq9,3327,47.881,0.72918959,0,0,,2.00E-128,P39880,Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1),Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1),GO:0000139; GO:0042491; GO:0003682; GO:0005829; GO:0001822; GO:0030324; GO:0007275; GO:0000122; GO:0005634; GO:0000301; GO:0043565; GO:0003700; GO:0006351,"Golgi membrane; auditory receptor cell differentiation; chromatin binding; cytosol; kidney development; lung development; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; nucleus; retrograde transport, vesicle recycling within Golgi; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02376;PF00046;,,,1.00E-25,ruditapes_c17947,,,,,CUX1_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite morphogenesis [GO:0050775]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; transcription, DNA-templated [GO:0006351]" comp141880_c0_seq2,2559,33.9586,0.97871813,1,436,female>male,1.00E-30,P27473,Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein),Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein),GO:0005737,cytoplasm,PF07534;,,,,,,,,,IFI44_PANTR,Pan troglodytes (Chimpanzee), comp141880_c0_seq6,2545,34.224,0.98234669,32,270,,8.00E-30,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,,,,,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp141884_c0_seq3,490,48.7755,0.83161955,0,6,,6.00E-07,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141884_c0_seq5,503,49.1054,0.89869593,6,17,,7.00E-07,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp141885_c0_seq3,3356,45.7986,0.48511565,495,1165,,0,P59470,DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B),DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B),GO:0003677; GO:0005666; GO:0003899; GO:0051607; GO:0045087; GO:0046872; GO:0045089; GO:0032728; GO:0032549; GO:0006351,"DNA binding; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase activity; defense response to virus; innate immune response; metal ion binding; positive regulation of innate immune response; positive regulation of interferon-beta production; ribonucleoside binding; transcription, DNA-dependent",PF04563;PF04561;PF04565;PF04566;PF04567;PF00562;PF04560;,0,CHOYP_RPC2.1.1,1.00E-120,ruditapes_c31431,,,,,RPC2_MOUSE,Mus musculus (Mouse),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription from RNA polymerase III promoter [GO:0006383] comp141889_c0_seq1,1508,41.5119,0.52958322,44,359,,1.00E-36,Q15054,DNA polymerase delta subunit 3 (DNA polymerase delta subunit p66),DNA polymerase delta subunit 3 (DNA polymerase delta subunit p66),GO:0006271; GO:0000731; GO:0003887; GO:0006284; GO:0043625; GO:0006298; GO:0005739; GO:0000278; GO:0005654; GO:0006297; GO:0000722; GO:0032201; GO:0006283,"DNA strand elongation involved in DNA replication; DNA synthesis involved in DNA repair; DNA-directed DNA polymerase activity; base-excision repair; delta DNA polymerase complex; mismatch repair; mitochondrion; mitotic cell cycle; nucleoplasm; nucleotide-excision repair, DNA gap filling; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair",PF09507;,,,,,,,,,DPOD3_HUMAN,Homo sapiens (Human),"DNA damage response, detection of DNA damage [GO:0042769]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in DNA repair [GO:0000731]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]" comp141890_c0_seq2,2868,39.8884,0.43207837,12,20,,,,,,,,,,,3.00E-26,ruditapes_c25638,,,,,,, comp141890_c1_seq2,1046,35.9465,0.32823217,43,30,,,,,,,,,,,2.00E-11,ruditapes_c31302,,,,,,, comp141891_c1_seq1,1434,41.0042,0.63994116,139,345,,8.00E-102,Q32L93,GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2),GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2),GO:0003920; GO:0046872; GO:0009117,GMP reductase activity; metal ion binding; nucleotide metabolic process,PF00478;,2.00E-172,CHOYP_GMPR2.1.1,,,,,,,GMPR2_BOVIN,Bos taurus (Bovine),GMP metabolic process [GO:0046037]; purine nucleobase metabolic process [GO:0006144] comp141891_c1_seq2,1026,41.3255,0.58068584,12,136,,3.00E-85,Q9P2T1,GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2),GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2),GO:0003920; GO:0005829; GO:0046872; GO:0009117; GO:0006144; GO:0043101,GMP reductase activity; cytosol; metal ion binding; nucleotide metabolic process; purine nucleobase metabolic process; purine-containing compound salvage,PF00478;,,,,,,,,,GMPR2_HUMAN,Homo sapiens (Human),GMP metabolic process [GO:0046037]; purine-containing compound salvage [GO:0043101]; purine nucleobase metabolic process [GO:0006144] comp141894_c0_seq2,2828,39.0382,0.54560334,4,58,,1.00E-167,P51006,Poly(A) polymerase type 3 (PAP) (EC 2.7.7.19) (Polynucleotide adenylyltransferase) (Fragment),Poly(A) polymerase type 3 (PAP) (EC 2.7.7.19) (Polynucleotide adenylyltransferase) (Fragment),GO:0005524; GO:0003723; GO:0043631; GO:0006397; GO:0046872; GO:0005634; GO:0004652,ATP binding; RNA binding; RNA polyadenylation; mRNA processing; metal ion binding; nucleus; polynucleotide adenylyltransferase activity,PF01909;PF04928;,4.00E-166,CHOYP_LOC101061332.1.1,,,,,,,PAPO3_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; RNA polyadenylation [GO:0043631] comp141894_c0_seq4,2353,39.4815,0.52223711,15,40,,0,Q9BWT3,Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme),Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme),GO:0005524; GO:0003723; GO:0006378; GO:0046872; GO:0005634; GO:0004652,ATP binding; RNA binding; mRNA polyadenylation; metal ion binding; nucleus; polynucleotide adenylyltransferase activity,PF01909;PF04928;PF04926;,,,,,,,,,PAPOG_HUMAN,Homo sapiens (Human),mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] comp141895_c0_seq1,1500,37,0.87191442,3,0,,8.00E-35,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp141895_c0_seq10,1177,35.9388,0.75409291,0,0,,3.00E-31,A9JTP3,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIRC7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966] comp141895_c0_seq14,534,34.8315,0.75096766,0,0,,3.00E-08,Q6TEM9,E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A),E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A),GO:0005737; GO:0005856; GO:0005829; GO:0007369; GO:0016874; GO:0030178; GO:0016567; GO:0008270,cytoplasm; cytoskeleton; cytosol; gastrulation; ligase activity; negative regulation of Wnt receptor signaling pathway; protein ubiquitination; zinc ion binding,PF00373;PF09379;,,,7.00E-19,ruditapes_c16242,,,,,MYLIA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567] comp141895_c0_seq15,1137,39.4019,0.81141709,0,0,,2.00E-33,Q60989,E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),GO:0016055; GO:0005737; GO:0005829; GO:1990001; GO:0043066; GO:0043524; GO:0051402; GO:0005634; GO:0048471; GO:0043234; GO:0004842; GO:0008270,Wnt receptor signaling pathway; cytoplasm; cytosol; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; neuron apoptotic process; nucleus; perinuclear region of cytoplasm; protein complex; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,XIAP_MOUSE,Mus musculus (Mouse),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055] comp141895_c0_seq16,984,39.2276,0.7961268,0,0,,2.00E-06,D3ZDI6,E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),GO:0006928; GO:0042632; GO:0005737; GO:0005856; GO:0019898; GO:0010989; GO:0007399; GO:0005886; GO:0045732; GO:0031648; GO:0042787; GO:0032803; GO:0004842; GO:0008270,cellular component movement; cholesterol homeostasis; cytoplasm; cytoskeleton; extrinsic to membrane; negative regulation of low-density lipoprotein particle clearance; nervous system development; plasma membrane; positive regulation of protein catabolic process; protein destabilization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of low-density lipoprotein particle receptor catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF09380;PF00373;PF09379;,,,,,,,,,MYLIP_RAT,Rattus norvegicus (Rat),cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803] comp141895_c0_seq19,1530,36.4706,0.85102871,5,15,,6.00E-41,A9JTP3,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIRC7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966] comp141895_c0_seq2,1230,40.3252,0.87020837,0,0,,1.00E-45,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp141895_c0_seq21,1564,36.8286,0.85193285,0,0,,6.00E-33,Q60989,E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),GO:0016055; GO:0005737; GO:0005829; GO:1990001; GO:0043066; GO:0043524; GO:0051402; GO:0005634; GO:0048471; GO:0043234; GO:0004842; GO:0008270,Wnt receptor signaling pathway; cytoplasm; cytosol; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; neuron apoptotic process; nucleus; perinuclear region of cytoplasm; protein complex; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,XIAP_MOUSE,Mus musculus (Mouse),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055] comp141895_c0_seq22,427,35.8314,0.83033965,0,0,,3.00E-08,Q7M3S9,RING finger protein B (Protein rngB),RING finger protein B (Protein rngB),GO:0005737; GO:0008270,cytoplasm; zinc ion binding,PF01344;,,,2.00E-31,ruditapes2_c1114,,,,,RNGB_DICDI,Dictyostelium discoideum (Slime mold), comp141895_c0_seq23,770,40.9091,0.74812126,0,0,,1.00E-15,Q13075,Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),GO:0005524; GO:0016323; GO:0004869; GO:0005737; GO:0006954; GO:0045087; GO:0046872; GO:0043154; GO:0043524; GO:0007399; GO:0017111,ATP binding; basolateral plasma membrane; cysteine-type endopeptidase inhibitor activity; cytoplasm; inflammatory response; innate immune response; metal ion binding; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of neuron apoptotic process; nervous system development; nucleoside-triphosphatase activity,PF00653;,,,,,,,,,BIRC1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678] comp141895_c0_seq26,829,32.2075,0.98408002,0,0,,,,,,,,,,,8.00E-27,ruditapes2_c803,,,,,,, comp141895_c0_seq28,472,34.5339,0.90095643,2,0,,3.00E-08,Q5E9J6,E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (RING finger protein 34),E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (RING finger protein 34),GO:0006915; GO:0012505; GO:0016874; GO:0016020; GO:0016607; GO:0016567; GO:0008270,apoptotic process; endomembrane system; ligase activity; membrane; nuclear speck; protein ubiquitination; zinc ion binding,,,,,,,,,,RNF34_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of oxygen metabolic process [GO:2000374]" comp141895_c0_seq3,1201,39.7169,0.88277925,0,0,,2.00E-06,D3ZDI6,E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR),GO:0006928; GO:0042632; GO:0005737; GO:0005856; GO:0019898; GO:0010989; GO:0007399; GO:0005886; GO:0045732; GO:0031648; GO:0042787; GO:0032803; GO:0004842; GO:0008270,cellular component movement; cholesterol homeostasis; cytoplasm; cytoskeleton; extrinsic to membrane; negative regulation of low-density lipoprotein particle clearance; nervous system development; plasma membrane; positive regulation of protein catabolic process; protein destabilization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of low-density lipoprotein particle receptor catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF09380;PF00373;PF09379;,,,,,,,,,MYLIP_RAT,Rattus norvegicus (Rat),cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803] comp141895_c0_seq31,1140,37.9825,0.79174317,0,0,,1.00E-07,Q6TEM9,E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A),E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A),GO:0005737; GO:0005856; GO:0005829; GO:0007369; GO:0016874; GO:0030178; GO:0016567; GO:0008270,cytoplasm; cytoskeleton; cytosol; gastrulation; ligase activity; negative regulation of Wnt receptor signaling pathway; protein ubiquitination; zinc ion binding,PF00373;PF09379;,,,,,,,,,MYLIA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567] comp141895_c0_seq33,1458,36.6255,0.81380187,0,0,,1.00E-28,Q95M71,Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2),Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2),GO:0006915; GO:0005737; GO:0008270,apoptotic process; cytoplasm; zinc ion binding,PF00653;,,,,,,,,,BIRC8_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),apoptotic process [GO:0006915] comp141895_c0_seq34,1233,39.0105,0.83875408,0,0,,4.00E-42,A9JTP3,Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIRC7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966] comp141895_c0_seq35,641,35.1014,0.775614,0,0,,3.00E-16,Q13489,Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (IAP-1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1),Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1),GO:0038061; GO:0035666; GO:0006915; GO:0007166; GO:0005829; GO:0045087; GO:0070266; GO:0043066; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0043123; GO:0039535; GO:2000116; GO:0050727; GO:0060544; GO:0070424; GO:0034121; GO:0034138; GO:0034142; GO:0004842; GO:0008270,NIK/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; apoptotic process; cell surface receptor signaling pathway; cytosol; innate immune response; necroptosis; negative regulation of apoptotic process; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of RIG-I signaling pathway; regulation of cysteine-type endopeptidase activity; regulation of inflammatory response; regulation of necroptosis; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,BIRC3_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; protein heterooligomerization [GO:0051291]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; spermatogenesis [GO:0007283]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp141895_c0_seq4,936,32.6923,0.97127913,0,0,,7.00E-07,Q5E9J6,E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (RING finger protein 34),E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (RING finger protein 34),GO:0006915; GO:0012505; GO:0016874; GO:0016020; GO:0016607; GO:0016567; GO:0008270,apoptotic process; endomembrane system; ligase activity; membrane; nuclear speck; protein ubiquitination; zinc ion binding,,,,,,,,,,RNF34_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of oxygen metabolic process [GO:2000374]" comp141895_c0_seq6,1268,38.0915,0.82495307,0,0,,1.00E-07,Q6TEM9,E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A),E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A),GO:0005737; GO:0005856; GO:0005829; GO:0007369; GO:0016874; GO:0030178; GO:0016567; GO:0008270,cytoplasm; cytoskeleton; cytosol; gastrulation; ligase activity; negative regulation of Wnt receptor signaling pathway; protein ubiquitination; zinc ion binding,PF00373;PF09379;,,,,,,,,,MYLIA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567] comp141895_c0_seq7,1529,37.5409,0.8814124,0,0,,8.00E-38,Q60989,E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP),GO:0016055; GO:0005737; GO:0005829; GO:1990001; GO:0043066; GO:0043524; GO:0051402; GO:0005634; GO:0048471; GO:0043234; GO:0004842; GO:0008270,Wnt receptor signaling pathway; cytoplasm; cytosol; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptotic process; neuron apoptotic process; nucleus; perinuclear region of cytoplasm; protein complex; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,XIAP_MOUSE,Mus musculus (Mouse),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055] comp141895_c0_seq9,1394,36.8006,0.83653712,0,0,,,,,,,,,,,2.00E-25,ruditapes_c580,,,,,,, comp141899_c0_seq2,1968,27.5407,0.62329867,69,121,,4.00E-33,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,3.00E-27,CHOYP_LOC100537145.2.3,8.00E-19,ruditapes_c27344,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp141899_c0_seq4,631,31.2203,0.58627234,13,17,,6.00E-07,P16425,Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,5.00E-30,CHOYP_LIN1.3.3,,,,,,,Y2R2_DROME,Drosophila melanogaster (Fruit fly), comp141899_c0_seq6,671,31.2966,0.6222236,16,3,,,,,,,,,,,4.00E-11,ruditapes_c28149,,,,,,, comp141899_c0_seq7,1148,27.0906,0.57594029,0,6,,,,,,,,,8.00E-50,CHOYP_LOC100562878.2.2,,,,,,,,, comp141901_c0_seq2,1051,42.7212,1.05839365,57,90,,3.00E-10,P77619,UPF0214 protein YfeW,UPF0214 protein YfeW,GO:0031226; GO:0008658; GO:0009002,intrinsic to plasma membrane; penicillin binding; serine-type D-Ala-D-Ala carboxypeptidase activity,PF00144;,,,,,,,,,YFEW_ECOLI,Escherichia coli (strain K12), comp141905_c0_seq1,3852,46.5732,0.28263255,0,0,,0,Q9Z2Q1,Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) (Vesicle-associated protein 1),Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) (Vesicle-associated protein 1),GO:0030134; GO:0012507; GO:0005789; GO:0005768; GO:0015031; GO:0016192,ER to Golgi transport vesicle; ER to Golgi transport vesicle membrane; endoplasmic reticulum membrane; endosome; protein transport; vesicle-mediated transport,PF12931;,0,CHOYP_SC31A.1.2,,,,,,,SC31A_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp141905_c0_seq2,3867,46.496,0.28245984,0,0,,0,Q3UPL0,Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A),Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A),GO:0030134; GO:0012507; GO:0005789; GO:0048471; GO:0015031; GO:0051592; GO:0030120; GO:0016192,ER to Golgi transport vesicle; ER to Golgi transport vesicle membrane; endoplasmic reticulum membrane; perinuclear region of cytoplasm; protein transport; response to calcium ion; vesicle coat; vesicle-mediated transport,PF12931;,0,CHOYP_SC31A.2.2,,,,,,,SC31A_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; response to calcium ion [GO:0051592]; vesicle-mediated transport [GO:0016192] comp141905_c0_seq3,3822,46.8603,0.28612416,0,0,,0,Q5R4F4,Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A),Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A),GO:0030134; GO:0012507; GO:0005789; GO:0015031; GO:0016192,ER to Golgi transport vesicle; ER to Golgi transport vesicle membrane; endoplasmic reticulum membrane; protein transport; vesicle-mediated transport,PF12931;,0,CHOYP_SC31A.1.2,,,,,,,SC31A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp141905_c0_seq4,3837,46.7813,0.28595698,0,0,,0,Q5R4F4,Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A),Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A),GO:0030134; GO:0012507; GO:0005789; GO:0015031; GO:0016192,ER to Golgi transport vesicle; ER to Golgi transport vesicle membrane; endoplasmic reticulum membrane; protein transport; vesicle-mediated transport,PF12931;,0,CHOYP_SC31A.2.2,,,,,,,SC31A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp141908_c0_seq1,1173,40.4092,0.33442554,54,109,,3.00E-15,Q8UVC1,Inversin,Inversin,GO:0016055; GO:0005737; GO:0005856; GO:0007275,Wnt receptor signaling pathway; cytoplasm; cytoskeleton; multicellular organismal development,PF00023;PF12796;,,,,,,,,,INVS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),body morphogenesis [GO:0010171]; cloaca development [GO:0035844]; convergent extension involved in gastrulation [GO:0060027]; establishment of planar polarity [GO:0001736]; heart looping [GO:0001947]; kidney development [GO:0001822]; opsin transport [GO:0036372]; pronephros formation [GO:0072116]; pronephros morphogenesis [GO:0072114]; Wnt signaling pathway [GO:0016055] comp141908_c0_seq2,1137,40.3694,0.36751548,0,17,,1.00E-15,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,,,1.00E-14,ruditapes_c9192,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp141908_c0_seq3,1166,40.4803,0.37718192,35,91,,8.00E-47,Q0P5B9,Ankyrin repeat domain-containing protein 39,Ankyrin repeat domain-containing protein 39,,,PF12796;,,,,,,,,,ANR39_BOVIN,Bos taurus (Bovine), comp141908_c0_seq4,1144,40.472,0.3418806,4,5,,6.00E-47,Q0P5B9,Ankyrin repeat domain-containing protein 39,Ankyrin repeat domain-containing protein 39,,,PF12796;,,,,,,,,,ANR39_BOVIN,Bos taurus (Bovine), comp141909_c1_seq10,1436,39.5543,1.00430615,0,0,,1.00E-06,P42297,Universal stress protein YxiE (USP YxiE),Universal stress protein YxiE (USP YxiE),GO:0006950,response to stress,PF00582;,3.00E-12,CHOYP_NEMVEDRAFT_V1G236658.2.6,,,,,,,YXIE_BACSU,Bacillus subtilis (strain 168),response to stress [GO:0006950] comp141909_c1_seq4,586,46.0751,1.14336134,0,0,,,,,,,,,1.00E-11,CHOYP_NEMVEDRAFT_V1G236658.1.6,,,,,,,,, comp141909_c1_seq5,1448,39.7099,1.0236047,0,0,,1.00E-06,P42297,Universal stress protein YxiE (USP YxiE),Universal stress protein YxiE (USP YxiE),GO:0006950,response to stress,PF00582;,,,,,,,,,YXIE_BACSU,Bacillus subtilis (strain 168),response to stress [GO:0006950] comp141909_c1_seq6,2068,37.1857,0.93822695,0,0,,1.00E-09,Q2FXL6,Putative universal stress protein SAOUHSC_01819,Putative universal stress protein SAOUHSC_01819,GO:0005737; GO:0006950,cytoplasm; response to stress,PF00582;,,,,,,,,,Y1819_STAA8,Staphylococcus aureus (strain NCTC 8325),response to stress [GO:0006950] comp141909_c1_seq7,1505,39.8007,1.01209722,0,0,,6.00E-10,Q2FXL6,Putative universal stress protein SAOUHSC_01819,Putative universal stress protein SAOUHSC_01819,GO:0005737; GO:0006950,cytoplasm; response to stress,PF00582;,,,,,,,,,Y1819_STAA8,Staphylococcus aureus (strain NCTC 8325),response to stress [GO:0006950] comp141909_c1_seq8,1999,36.9185,0.92635503,0,0,,,,,,,,,4.00E-12,CHOYP_NEMVEDRAFT_V1G236658.2.6,,,,,,,,, comp141909_c1_seq9,2011,36.9965,0.94603611,0,2,,,,,,,,,4.00E-12,CHOYP_NEMVEDRAFT_V1G236658.2.6,2.00E-20,ruditapes_c3215,,,,,,, comp141911_c0_seq2,692,36.9942,0.38751246,37,410,,5.00E-29,Q9CWB7,Glutaredoxin-like protein C5orf63 homolog,Glutaredoxin-like protein C5orf63 homolog,GO:0005739; GO:0055114,mitochondrion; oxidation-reduction process,PF05768;,,,,,,,,,YD286_MOUSE,Mus musculus (Mouse),oxidation-reduction process [GO:0055114] comp141914_c0_seq1,903,43.8538,0.32941217,43,55,,1.00E-59,Q1LWH4,Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15),Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15),GO:0008409; GO:0017108; GO:0000724; GO:0046872; GO:0033683; GO:0005634; GO:0004528; GO:0043130,"5'-3' exonuclease activity; 5'-flap endonuclease activity; double-strand break repair via homologous recombination; metal ion binding; nucleotide-excision repair, DNA incision; nucleus; phosphodiesterase I activity; ubiquitin binding",PF08774;,,,,,,,,,FAN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]" comp141915_c0_seq1,3484,39.9828,0.58210674,303,1040,,0,Q6P2K6,Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1),Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1),GO:0005737; GO:0005815; GO:0005634; GO:0045722; GO:0006470; GO:0030289,cytoplasm; microtubule organizing center; nucleus; positive regulation of gluconeogenesis; protein dephosphorylation; protein phosphatase 4 complex,PF04802;,0,CHOYP_P4R3A.1.1,,,,,,,P4R3A_MOUSE,Mus musculus (Mouse),positive regulation of gluconeogenesis [GO:0045722]; protein dephosphorylation [GO:0006470] comp141916_c1_seq3,2604,48.6559,0.54464289,150,64,,0,Q8K4P0,pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146),pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146),GO:0005581; GO:0006397; GO:0005634,collagen; mRNA processing; nucleus,PF00400;,,,,,,,,,WDR33_MOUSE,Mus musculus (Mouse),mRNA cleavage [GO:0006379]; mRNA processing [GO:0006397] comp141916_c1_seq4,1810,48.2873,0.62746215,8,0,,0,Q9C0J8,pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146),pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146),GO:0005581; GO:0006397; GO:0005634; GO:0006301; GO:0007283,collagen; mRNA processing; nucleus; postreplication repair; spermatogenesis,PF00400;,0,CHOYP_LOC100693575.1.1,,,,,,,WDR33_HUMAN,Homo sapiens (Human),mRNA cleavage [GO:0006379]; mRNA processing [GO:0006397]; postreplication repair [GO:0006301]; spermatogenesis [GO:0007283] comp141917_c0_seq3,2087,44.6574,0.58653049,430,388,,4.00E-13,Q9WUU8,TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN) (ABIN-1) (Nef-associated factor 1) (Naf1) (Virion-associated nuclear shuttling protein) (VAN) (mVAN),TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN) (ABIN-1) (Nef-associated factor 1) (Naf1) (Virion-associated nuclear shuttling protein) (VAN) (mVAN),GO:0002755; GO:0005737; GO:0006954; GO:0007159; GO:0051019; GO:0070373; GO:0043124; GO:0005634; GO:0031593; GO:0050729; GO:0045944,MyD88-dependent toll-like receptor signaling pathway; cytoplasm; inflammatory response; leukocyte cell-cell adhesion; mitogen-activated protein kinase binding; negative regulation of ERK1 and ERK2 cascade; negative regulation of I-kappaB kinase/NF-kappaB cascade; nucleus; polyubiquitin binding; positive regulation of inflammatory response; positive regulation of transcription from RNA polymerase II promoter,,,,,,,,,,TNIP1_MOUSE,Mus musculus (Mouse),glycoprotein biosynthetic process [GO:0009101]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade [GO:0085032]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; positive regulation of inflammatory response [GO:0050729]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteolysis [GO:0006508] comp141918_c0_seq2,3150,41.8413,0.41751111,71,403,,,,,,,,,1.00E-121,CHOYP_LOC100485159.1.1,,,,,,,,, comp141919_c0_seq1,1843,34.726,0.34362842,55,165,,9.00E-22,Q9ESN5,Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis),Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis),GO:0000777; GO:0005634; GO:0045944,condensed chromosome kinetochore; nucleus; positive regulation of transcription from RNA polymerase II promoter,PF11802;,,,,,,,,,CENPK_MOUSE,Mus musculus (Mouse),positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp141920_c0_seq1,1081,34.2276,0.48791528,0,0,,2.00E-10,P26453,Basigin (Glycoprotein CE9) (OX-47 antigen) (CD antigen CD147),Basigin (Glycoprotein CE9) (OX-47 antigen) (CD antigen CD147),GO:0002080; GO:0046697; GO:0007566; GO:0016021; GO:0005537; GO:0042470; GO:0045121; GO:0005739; GO:0042475; GO:0051591; GO:0046689; GO:0043434; GO:0042383,acrosomal membrane; decidualization; embryo implantation; integral to membrane; mannose binding; melanosome; membrane raft; mitochondrion; odontogenesis of dentin-containing tooth; response to cAMP; response to mercury ion; response to peptide hormone stimulus; sarcolemma,,,,,,,,,,BASI_RAT,Rattus norvegicus (Rat),decidualization [GO:0046697]; embryo implantation [GO:0007566]; odontogenesis of dentin-containing tooth [GO:0042475]; protein targeting to plasma membrane [GO:0072661]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434] comp141920_c0_seq10,1048,33.874,0.47846528,0,0,,,,,,,,,3.00E-17,CHOYP_NPTN.1.1,,,,,,,,, comp141920_c0_seq11,1079,34.291,0.45454584,0,0,,3.00E-10,P17790,Basigin (5A11 antigen) (Blood-brain barrier HT7 antigen) (Neurothelin),Basigin (5A11 antigen) (Blood-brain barrier HT7 antigen) (Neurothelin),GO:0002080; GO:0016021; GO:0006090,acrosomal membrane; integral to membrane; pyruvate metabolic process,,,,,,,,,,BASI_CHICK,Gallus gallus (Chicken), comp141920_c0_seq3,1002,45.2096,0.5104131,185,474,,3.00E-15,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp141920_c0_seq5,1063,34.2427,0.46226456,0,0,,3.00E-10,P17790,Basigin (5A11 antigen) (Blood-brain barrier HT7 antigen) (Neurothelin),Basigin (5A11 antigen) (Blood-brain barrier HT7 antigen) (Neurothelin),GO:0002080; GO:0016021; GO:0006090,acrosomal membrane; integral to membrane; pyruvate metabolic process,,,,,,,,,,BASI_CHICK,Gallus gallus (Chicken), comp141920_c0_seq6,1082,34.1035,0.48975019,6,3,,2.00E-10,P26453,Basigin (Glycoprotein CE9) (OX-47 antigen) (CD antigen CD147),Basigin (Glycoprotein CE9) (OX-47 antigen) (CD antigen CD147),GO:0002080; GO:0046697; GO:0007566; GO:0016021; GO:0005537; GO:0042470; GO:0045121; GO:0005739; GO:0042475; GO:0051591; GO:0046689; GO:0043434; GO:0042383,acrosomal membrane; decidualization; embryo implantation; integral to membrane; mannose binding; melanosome; membrane raft; mitochondrion; odontogenesis of dentin-containing tooth; response to cAMP; response to mercury ion; response to peptide hormone stimulus; sarcolemma,,,,,,,,,,BASI_RAT,Rattus norvegicus (Rat),decidualization [GO:0046697]; embryo implantation [GO:0007566]; odontogenesis of dentin-containing tooth [GO:0042475]; protein targeting to plasma membrane [GO:0072661]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434] comp141920_c0_seq9,1064,34.0226,0.46710568,0,0,,,,,,,,,3.00E-17,CHOYP_NPTN.1.1,,,,,,,,, comp141923_c3_seq1,2012,32.6541,0.43533748,0,0,,,,,,,,,4.00E-12,CHOYP_LOC100640513.1.1,,,,,,,,, comp141923_c3_seq2,2695,31.6883,0.43384224,0,0,,,,,,,,,1.00E-13,CHOYP_contig_054220,,,,,,,,, comp141923_c3_seq4,2676,31.577,0.42483399,0,0,,,,,,,,,2.00E-11,CHOYP_contig_054030,,,,,,,,, comp141923_c3_seq5,2053,32.6352,0.44529567,20,213,,,,,,,,,4.00E-12,CHOYP_LOC100640513.1.1,,,,,,,,, comp141923_c3_seq6,2698,31.4678,0.42403776,0,0,,,,,,,,,1.00E-13,CHOYP_contig_054220,1.00E-11,ruditapes_c12888,,,,,,, comp141923_c3_seq7,2031,32.7917,0.44622983,0,0,,,,,,,,,5.00E-11,CHOYP_contig_054030,,,,,,,,, comp141923_c3_seq8,2034,32.4975,0.43439332,1,6,,,,,,,,,4.00E-12,CHOYP_LOC100640513.1.1,,,,,,,,, comp141924_c2_seq1,1956,35.8896,0.79793823,16,101,,2.00E-41,P09496,Clathrin light chain A (Lca),Clathrin light chain A (Lca),GO:0019886; GO:0007411; GO:0030118; GO:0030132; GO:0030130; GO:0030669; GO:0005829; GO:0006897; GO:0007173; GO:0006886; GO:0042059; GO:0048011; GO:0042277; GO:0005886; GO:0006892; GO:0005198; GO:0032588,antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin-coated endocytic vesicle membrane; cytosol; endocytosis; epidermal growth factor receptor signaling pathway; intracellular protein transport; negative regulation of epidermal growth factor receptor signaling pathway; neurotrophin TRK receptor signaling pathway; peptide binding; plasma membrane; post-Golgi vesicle-mediated transport; structural molecule activity; trans-Golgi network membrane,PF01086;,,,,,,,,,CLCA_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; clathrin-mediated endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; microtubule-based movement [GO:0007018]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp141924_c2_seq2,1899,35.545,0.75007199,135,471,,,,,,,,,1.00E-25,CHOYP_CLCA.1.1,,,,,,,,, comp141924_c2_seq4,2842,34.9754,0.61625142,37,127,,2.00E-28,Q9VWA1,Clathrin light chain (dClc),Clathrin light chain (dClc),GO:0030132; GO:0030130; GO:0030125; GO:0005905; GO:0006886; GO:0007269; GO:0005198; GO:0008021; GO:0016183,clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin vesicle coat; coated pit; intracellular protein transport; neurotransmitter secretion; structural molecule activity; synaptic vesicle; synaptic vesicle coating,PF01086;,2.00E-25,CHOYP_CLCA.1.1,1.00E-99,ruditapes2_c781,,,,,CLC_DROME,Drosophila melanogaster (Fruit fly),clathrin-mediated endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; neurotransmitter secretion [GO:0007269]; sensory perception of pain [GO:0019233]; synaptic vesicle coating [GO:0016183] comp141924_c2_seq5,1550,36.8387,0.75310041,1,12,,9.00E-44,P09496,Clathrin light chain A (Lca),Clathrin light chain A (Lca),GO:0019886; GO:0007411; GO:0030118; GO:0030132; GO:0030130; GO:0030669; GO:0005829; GO:0006897; GO:0007173; GO:0006886; GO:0042059; GO:0048011; GO:0042277; GO:0005886; GO:0006892; GO:0005198; GO:0032588,antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin-coated endocytic vesicle membrane; cytosol; endocytosis; epidermal growth factor receptor signaling pathway; intracellular protein transport; negative regulation of epidermal growth factor receptor signaling pathway; neurotrophin TRK receptor signaling pathway; peptide binding; plasma membrane; post-Golgi vesicle-mediated transport; structural molecule activity; trans-Golgi network membrane,PF01086;,,,,,,,,,CLCA_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; clathrin-mediated endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; microtubule-based movement [GO:0007018]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp141928_c0_seq1,3813,43.1419,0.66568513,8,28,,0,Q63470,Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.2) (Dual specificity YAK1-related kinase) (Protein kinase minibrain homolog) (MNBH) (RP86),Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.2) (Dual specificity YAK1-related kinase) (Protein kinase minibrain homolog) (MNBH) (RP86),GO:0005524; GO:0007623; GO:0043518; GO:0007399; GO:0004715; GO:0016607; GO:0018105; GO:0018107; GO:0090312; GO:0046777; GO:0043621; GO:0004674; GO:0004713; GO:0030100,"ATP binding; circadian rhythm; negative regulation of DNA damage response, signal transduction by p53 class mediator; nervous system development; non-membrane spanning protein tyrosine kinase activity; nuclear speck; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of protein deacetylation; protein autophosphorylation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of endocytosis",PF00069;,0,CHOYP_MNB.1.1,,,,,,,DYR1A_RAT,Rattus norvegicus (Rat),"circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein deacetylation [GO:0090312]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp141928_c0_seq2,4032,42.9563,0.67331514,12,0,,,,,,,,,0,CHOYP_MNB.1.1,,,,,,,,, comp141928_c0_seq3,3731,43.3128,0.66324832,0,7,,0,Q61214,Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (MP86) (Protein kinase minibrain homolog) (MNBH),Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (MP86) (Protein kinase minibrain homolog) (MNBH),GO:0005524; GO:0007623; GO:0043518; GO:0004715; GO:0016607; GO:0018105; GO:0018107; GO:0090312; GO:0046777; GO:0004674; GO:0004712; GO:0030529,"ATP binding; circadian rhythm; negative regulation of DNA damage response, signal transduction by p53 class mediator; non-membrane spanning protein tyrosine kinase activity; nuclear speck; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of protein deacetylation; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; ribonucleoprotein complex",PF00069;,,,,,,,,,DYR1A_MOUSE,Mus musculus (Mouse),"circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein deacetylation [GO:0090312]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp141928_c0_seq4,2889,42.783,0.59857414,1,0,,3.00E-13,P85051,Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.2) (Dual specificity YAK1-related kinase) (Protein kinase minibrain homolog) (MNBH) (RP86) (Fragments),Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.2) (Dual specificity YAK1-related kinase) (Protein kinase minibrain homolog) (MNBH) (RP86) (Fragments),GO:0005524; GO:0007623; GO:0016607; GO:0018108; GO:0046777; GO:0004674; GO:0004713,ATP binding; circadian rhythm; nuclear speck; peptidyl-tyrosine phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,,,,,,,,,,DYR1A_RABIT,Oryctolagus cuniculus (Rabbit),circadian rhythm [GO:0007623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp141930_c0_seq1,2158,41.2882,0.47337327,204,179,,1.00E-24,G3MWR8,Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3),GO:0071949; GO:0003779; GO:0030042; GO:0005737; GO:0005856; GO:0006887; GO:0016709; GO:0008270,"FAD binding; actin binding; actin filament depolymerization; cytoplasm; cytoskeleton; exocytosis; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; zinc ion binding",PF00307;PF12130;PF01494;PF00412;,3.00E-45,CHOYP_MCA3A.2.2,2.00E-52,ruditapes_c15043,,,,,MICA3_BOVIN,Bos taurus (Bovine),actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114] comp141930_c0_seq3,755,40.2649,0.64196761,27,71,,,,,,,,,2.00E-16,CHOYP_contig_023089,,,,,,,,, comp141934_c3_seq2,1555,30.1608,0.45472165,198,500,,,,,,,,,,,7.00E-12,ruditapes_c8275,,,,,,, comp141934_c5_seq1,2295,43.4423,0.28118652,7,25,,0,Q5EBD9,Elongator complex protein 2 (ELP2),Elongator complex protein 2 (ELP2),GO:0005737; GO:0061133; GO:0005634; GO:0043248; GO:0000502; GO:0006355; GO:0006368,"cytoplasm; endopeptidase activator activity; nucleus; proteasome assembly; proteasome complex; regulation of transcription, DNA-dependent; transcription elongation from RNA polymerase II promoter",PF00400;,1.00E-76,CHOYP_ELP2.1.1,,,,,,,ELP2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),proteasome assembly [GO:0043248]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp141934_c5_seq2,2895,43.4542,0.26731214,35,276,,0,Q05AM5,Elongator complex protein 2 (ELP2),Elongator complex protein 2 (ELP2),GO:0005737; GO:0061133; GO:0005634; GO:0043248; GO:0000502; GO:0006355; GO:0006368,"cytoplasm; endopeptidase activator activity; nucleus; proteasome assembly; proteasome complex; regulation of transcription, DNA-dependent; transcription elongation from RNA polymerase II promoter",PF00400;,,,,,,,,,ELP2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),proteasome assembly [GO:0043248]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp141935_c0_seq1,1569,35.7553,0.55755797,559,1191,,4.00E-96,Q8NBN7,Retinol dehydrogenase 13 (EC 1.1.1.-),Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3),GO:0005739; GO:0016491,mitochondrion; oxidoreductase activity,PF00106;,,,,,,,,,RDH13_HUMAN,Homo sapiens (Human),eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842] comp141938_c1_seq1,1461,41.8207,0.89618057,180,473,,9.00E-128,O83041,Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),GO:0004177; GO:0005737; GO:0006508,aminopeptidase activity; cytoplasm; proteolysis,PF00561;,6.00E-21,CHOYP_CAOG_02976.2.2,,,,,,,PIP_PLEBO,Leptolyngbya boryana (Plectonema boryanum), comp141939_c0_seq2,2078,37.2955,0.22309864,61,5,,3.00E-163,A7MBF6,Uncharacterized protein C1orf228 homolog,Uncharacterized protein C1orf228 homolog,,,,0,CHOYP_LOC100375249.1.1,,,0,AM857837.p.cg.6,5,,CA228_BOVIN,Bos taurus (Bovine), comp141941_c0_seq1,1339,32.4869,0.45333471,20,136,,1.00E-38,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,1.00E-60,CHOYP_LOC100892567.2.8,4.00E-20,ruditapes_c9179,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141946_c2_seq1,3409,38.2517,0.7466398,0,0,,2.00E-19,O34962,Probable NAD-dependent malic enzyme 4 (NAD-ME 4) (EC 1.1.1.38),Probable NAD-dependent malic enzyme 4 (NAD-ME 4) (EC 1.1.1.38),GO:0051287; GO:0016619; GO:0006108; GO:0046872,NAD binding; malate dehydrogenase (oxaloacetate-decarboxylating) activity; malate metabolic process; metal ion binding,PF00390;PF03949;,1.00E-166,CHOYP_LOC100743251.1.1,,,,,,,MAO4_BACSU,Bacillus subtilis (strain 168),malate metabolic process [GO:0006108] comp141946_c2_seq2,3868,39.0383,0.80119129,13,71,,0,Q8BMF3,"NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)","NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)",GO:0051287; GO:0004473; GO:0016619; GO:0006108; GO:0046872; GO:0005759; GO:0005739; GO:0006090,NAD binding; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity; malate dehydrogenase (oxaloacetate-decarboxylating) activity; malate metabolic process; metal ion binding; mitochondrial matrix; mitochondrion; pyruvate metabolic process,PF00390;PF03949;,0,CHOYP_LOC100743251.1.1,,,,,,,MAON_MOUSE,Mus musculus (Mouse),malate metabolic process [GO:0006108]; oxidation-reduction process [GO:0055114]; pyruvate metabolic process [GO:0006090] comp141946_c2_seq3,3395,38.2032,0.74365206,0,0,,6.00E-26,P16468,NAD-dependent malic enzyme (NAD-ME) (EC 1.1.1.38),NAD-dependent malic enzyme (NAD-ME) (EC 1.1.1.38),GO:0051287; GO:0016619; GO:0006108; GO:0046872,NAD binding; malate dehydrogenase (oxaloacetate-decarboxylating) activity; malate metabolic process; metal ion binding,PF00390;PF03949;,,,4.00E-107,ruditapes_c1419,,,,,MAOX_GEOSE,Geobacillus stearothermophilus (Bacillus stearothermophilus),malate metabolic process [GO:0006108] comp141946_c2_seq4,3882,39.0778,0.81016801,0,0,,0,Q8BMF3,"NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)","NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)",GO:0051287; GO:0004473; GO:0016619; GO:0006108; GO:0046872; GO:0005759; GO:0005739; GO:0006090,NAD binding; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity; malate dehydrogenase (oxaloacetate-decarboxylating) activity; malate metabolic process; metal ion binding; mitochondrial matrix; mitochondrion; pyruvate metabolic process,PF00390;PF03949;,2.00E-77,CHOYP_ME3.1.1,,,,,,,MAON_MOUSE,Mus musculus (Mouse),malate metabolic process [GO:0006108]; oxidation-reduction process [GO:0055114]; pyruvate metabolic process [GO:0006090] comp141946_c5_seq1,1054,43.5484,0.98152667,43,1643,,6.00E-31,P09478,Acetylcholine receptor subunit alpha-like 1,Acetylcholine receptor subunit alpha-like 1 (Nicotinic acetylcholine receptor alpha 1),GO:0004889; GO:0005892; GO:0030054; GO:0045211; GO:0017085; GO:0007271,"acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; cell junction; postsynaptic membrane; response to insecticide; synaptic transmission, cholinergic",PF02931;PF02932;,,,,,,,,,ACH1_DROME,Drosophila melanogaster (Fruit fly),"cation transport [GO:0006812]; neuromuscular synaptic transmission [GO:0007274]; response to insecticide [GO:0017085]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" comp141950_c0_seq1,2407,33.1118,0.57708667,1689,5621,,9.00E-10,Q9JKS4,LIM domain-binding protein 3 (Protein cypher) (Protein oracle) (Z-band alternatively spliced PDZ-motif protein),LIM domain-binding protein 3 (Protein cypher) (Protein oracle) (Z-band alternatively spliced PDZ-motif protein),GO:0030018; GO:0005856; GO:0051371; GO:0048471; GO:0005080; GO:0031143; GO:0045214; GO:0008270,Z disc; cytoskeleton; muscle alpha-actinin binding; perinuclear region of cytoplasm; protein kinase C binding; pseudopodium; sarcomere organization; zinc ion binding,PF15936;PF00412;PF00595;,,,,,,,,,LDB3_MOUSE,Mus musculus (Mouse),sarcomere organization [GO:0045214] comp141951_c2_seq2,849,49.47,0.55510281,100,179,,3.00E-52,Q25092,Laminin subunit B (Fragment),Laminin subunit B (Fragment),GO:0005578,proteinaceous extracellular matrix,PF00053;,2.00E-42,CHOYP_LOC100371750.2.2,,,,,,,LAMB_HIRME,Hirudo medicinalis (Medicinal leech), comp141951_c3_seq2,1865,48.4182,0.55674918,12,0,,1.00E-12,O00468,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0007213; GO:0005796; GO:0007411; GO:0005605; GO:0005509; GO:0005975; GO:0030054; GO:0035374; GO:0030204; GO:0045162; GO:0002162; GO:0030198; GO:0006024; GO:0006027; GO:0043395; GO:0016021; GO:0043236; GO:0043202; GO:0007603; GO:0005886; GO:0032321; GO:0051491; GO:0045887; GO:0045944; GO:0043113; GO:0001523; GO:0033691; GO:0005200; GO:0045202; GO:0050808,"G-protein coupled acetylcholine receptor signaling pathway; Golgi lumen; axon guidance; basal lamina; calcium ion binding; carbohydrate metabolic process; cell junction; chondroitin sulfate binding; chondroitin sulfate metabolic process; clustering of voltage-gated sodium channels; dystroglycan binding; extracellular matrix organization; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; heparan sulfate proteoglycan binding; integral to membrane; laminin binding; lysosomal lumen; phototransduction, visible light; plasma membrane; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; retinoid metabolic process; sialic acid binding; structural constituent of cytoskeleton; synapse; synapse organization",PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;,1.00E-12,CHOYP_LOC100371750.1.2,,,,,,,AGRIN_HUMAN,Homo sapiens (Human),clustering of voltage-gated sodium channels [GO:0045162]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]; retinoid metabolic process [GO:0001523]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp141951_c3_seq3,831,47.1721,0.45749065,0,15,,3.00E-27,Q16363,Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha),Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha),GO:0005605; GO:0001568; GO:0050873; GO:0007155; GO:0030198; GO:0005201; GO:0070062; GO:0005606; GO:0030155; GO:0030334; GO:0045995,basal lamina; blood vessel development; brown fat cell differentiation; cell adhesion; extracellular matrix organization; extracellular matrix structural constituent; extracellular vesicular exosome; laminin-1 complex; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development,PF00053;PF00054;PF02210;PF06008;PF06009;,,,,,,,,,LAMA4_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995] comp141951_c3_seq4,3144,45.6425,0.55665255,68,229,,0,P02469,Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta),Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta),GO:0007155; GO:0016477; GO:0007566; GO:0005201; GO:0043208; GO:0005178; GO:0005606; GO:0043259; GO:0005607; GO:0043257; GO:0007611; GO:0007162; GO:0031175; GO:0042476; GO:0048471; GO:0030335,cell adhesion; cell migration; embryo implantation; extracellular matrix structural constituent; glycosphingolipid binding; integrin binding; laminin-1 complex; laminin-10 complex; laminin-2 complex; laminin-8 complex; learning or memory; negative regulation of cell adhesion; neuron projection development; odontogenesis; perinuclear region of cytoplasm; positive regulation of cell migration,PF00053;PF00055;,5.00E-140,CHOYP_LOC100371750.2.2,,,,,,,LAMB1_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; cell migration [GO:0016477]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; learning or memory [GO:0007611]; negative regulation of cell adhesion [GO:0007162]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; neuron projection development [GO:0031175]; odontogenesis [GO:0042476]; positive regulation of cell migration [GO:0030335]; substrate adhesion-dependent cell spreading [GO:0034446] comp141952_c0_seq1,958,43.6326,0.35917642,48,49,,1.00E-49,Q800K6,DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP),DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP),GO:0003677; GO:0006281; GO:0000076; GO:0006270; GO:0071165; GO:0000785; GO:0003682; GO:0005737; GO:0005815; GO:0005634; GO:0035563; GO:0033138; GO:0045860; GO:0071168; GO:0030174; GO:0006974; GO:0000922,DNA binding; DNA repair; DNA replication checkpoint; DNA replication initiation; GINS complex assembly; chromatin; chromatin binding; cytoplasm; microtubule organizing center; nucleus; positive regulation of chromatin binding; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase activity; protein localization to chromatin; regulation of DNA-dependent DNA replication initiation; response to DNA damage stimulus; spindle pole,PF00533;PF12738;,,,,,,,,,TOB1A_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp141952_c0_seq2,2725,42.1651,0.38232824,248,182,,1.00E-43,Q92547,DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1),DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1),GO:0003677; GO:0006281; GO:0016605; GO:0005694; GO:0000794; GO:0005737; GO:0001673; GO:0005815; GO:0008022; GO:0010212; GO:0000922,DNA binding; DNA repair; PML body; chromosome; condensed nuclear chromosome; cytoplasm; male germ cell nucleus; microtubule organizing center; protein C-terminus binding; response to ionizing radiation; spindle pole,PF00533;PF12738;,1.00E-27,CHOYP_TOPB1.1.1,,,,,,,TOPB1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to ionizing radiation [GO:0010212] comp141954_c1_seq1,2765,43.0018,0.36185248,11,0,,2.00E-139,Q5SNQ7,Protein SERAC1 (Serine active site-containing protein 1),Protein SERAC1 (Serine active site-containing protein 1),GO:0006505; GO:0005783; GO:0016788; GO:0016021; GO:0006886; GO:0005739; GO:0008654,"GPI anchor metabolic process; endoplasmic reticulum; hydrolase activity, acting on ester bonds; integral to membrane; intracellular protein transport; mitochondrion; phospholipid biosynthetic process",,,,,,,,,,SRAC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phospholipid biosynthetic process [GO:0008654] comp141954_c1_seq3,2810,41.3167,0.40321795,64,29,,6.00E-147,Q5SNQ7,Protein SERAC1 (Serine active site-containing protein 1),Protein SERAC1 (Serine active site-containing protein 1),GO:0006505; GO:0005783; GO:0016788; GO:0016021; GO:0006886; GO:0005739; GO:0008654,"GPI anchor metabolic process; endoplasmic reticulum; hydrolase activity, acting on ester bonds; integral to membrane; intracellular protein transport; mitochondrion; phospholipid biosynthetic process",,,,,,,,,,SRAC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phospholipid biosynthetic process [GO:0008654] comp141955_c0_seq1,2437,38.0796,0.51052611,0,0,,3.00E-08,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141955_c0_seq2,1827,41.2151,0.73505863,43,66,,4.00E-71,Q6P1J6,"Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]","Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]",GO:0016324; GO:0046474; GO:0016021; GO:0016042; GO:0004622; GO:0036151; GO:0004623; GO:0007603; GO:0005886; GO:0001523,"apical plasma membrane; glycerophospholipid biosynthetic process; integral to membrane; lipid catabolic process; lysophospholipase activity; phosphatidylcholine acyl-chain remodeling; phospholipase A2 activity; phototransduction, visible light; plasma membrane; retinoid metabolic process",PF00657;,,,,,,,,,PLB1_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; positive regulation of acrosome reaction [GO:2000344]; retinoid metabolic process [GO:0001523] comp141955_c0_seq3,1999,40.02,0.70007018,0,0,,6.00E-73,Q06HQ7,"Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]","Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]",GO:0016324; GO:0016021; GO:0016042; GO:0004622; GO:0004623,apical plasma membrane; integral to membrane; lipid catabolic process; lysophospholipase activity; phospholipase A2 activity,PF00657;,,,,,,,,,PLB1_MONDO,Monodelphis domestica (Gray short-tailed opossum),lipid catabolic process [GO:0016042] comp141955_c0_seq4,1908,40.7757,0.71920626,0,0,,1.00E-78,Q06HQ7,"Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]","Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]",GO:0016324; GO:0016021; GO:0016042; GO:0004622; GO:0004623,apical plasma membrane; integral to membrane; lipid catabolic process; lysophospholipase activity; phospholipase A2 activity,PF00657;,,,1.00E-60,ruditapes2_c205,,,,,PLB1_MONDO,Monodelphis domestica (Gray short-tailed opossum),lipid catabolic process [GO:0016042] comp141955_c0_seq5,2609,37.4473,0.48186105,0,0,,3.00E-06,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141955_c0_seq6,2518,37.9269,0.49775184,0,0,,3.00E-08,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp141956_c0_seq1,2723,47.5578,0.72302423,758,176,,2.00E-169,Q5ZKK5,Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2),Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2),GO:0030154; GO:0005929; GO:0005737; GO:0005874; GO:0005815; GO:0007275; GO:0007283,cell differentiation; cilium; cytoplasm; microtubule; microtubule organizing center; multicellular organismal development; spermatogenesis,,2.00E-101,CHOYP_LOC100366442.4.4,,,,,,,ODFP2_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp141956_c0_seq2,1255,49.6414,0.70099663,47,0,,8.00E-15,Q2MJU7,Outer dense fiber protein 2 (84 kDa outer dense fiber protein) (Cenexin) (Outer dense fiber of sperm tails protein 2) (Fragment),Outer dense fiber protein 2 (84 kDa outer dense fiber protein) (Cenexin) (Outer dense fiber of sperm tails protein 2) (Fragment),GO:0030154; GO:0005814; GO:0005929; GO:0005874; GO:0007275; GO:0007283; GO:0000922,cell differentiation; centriole; cilium; microtubule; multicellular organismal development; spermatogenesis; spindle pole,,1.00E-36,CHOYP_LOC100366442.4.4,8.00E-23,ruditapes_c17341,,,,,ODFP2_MESAU,Mesocricetus auratus (Golden hamster),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp141957_c0_seq2,2594,44.9884,1.02245878,90,389,,0,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp141958_c0_seq1,2813,41.9836,0.70925661,136,279,,2.00E-28,Q05519,"Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)","Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)",GO:0003723; GO:0031124; GO:0006406; GO:0000398; GO:0005654; GO:0000166; GO:0006369,"RNA binding; mRNA 3'-end processing; mRNA export from nucleus; mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding; termination of RNA polymerase II transcription",PF00076;,2.00E-67,CHOYP_LOC100370236.1.3,2.00E-34,ruditapes_c7784,,,,,SRS11_HUMAN,Homo sapiens (Human),"mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]" comp141958_c0_seq2,2852,41.9004,0.69486478,140,471,,3.00E-52,O01159,"Probable splicing factor, arginine/serine-rich 7 (p54)","Probable splicing factor, arginine/serine-rich 7 (p54)",GO:0003723; GO:0000398; GO:0000166; GO:0005634,"RNA binding; mRNA splicing, via spliceosome; nucleotide binding; nucleus",PF00076;,1.00E-65,CHOYP_LOC100370236.2.3,,,,,,,RSP7_CAEEL,Caenorhabditis elegans,"mRNA splicing, via spliceosome [GO:0000398]" comp141960_c1_seq3,1293,49.3426,0.6454513,13,72,,5.00E-69,Q6NS15,Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (xARC105) (Mediator complex subunit 15),Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (xARC105) (Mediator complex subunit 15),GO:0001104; GO:0005737; GO:0016592,RNA polymerase II transcription cofactor activity; cytoplasm; mediator complex,PF09606;,6.00E-14,CHOYP_MED15.3.3,,,,,,,MED15_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp141962_c1_seq1,2543,39.363,0.87402438,29,136,,6.00E-54,P37967,Para-nitrobenzyl esterase (EC 3.1.1.-) (Intracellular esterase B) (PNB carboxy-esterase) (PNBCE),Para-nitrobenzyl esterase (EC 3.1.1.-) (Intracellular esterase B) (PNB carboxy-esterase) (PNBCE),GO:0004091; GO:0004104,carboxylesterase activity; cholinesterase activity,PF00135;,,,,,,,,,PNBA_BACSU,Bacillus subtilis (strain 168), comp141962_c1_seq2,2530,39.4071,0.86627139,0,47,,7.00E-56,P23654,Neurotactin,Neurotactin,GO:0007411; GO:0007413; GO:0016323; GO:0004091; GO:0007155; GO:0007417; GO:0016021,axon guidance; axonal fasciculation; basolateral plasma membrane; carboxylesterase activity; cell adhesion; central nervous system development; integral to membrane,PF00135;,,,,,,,,,NRT_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416] comp141963_c6_seq12,549,29.326,0.5239776,45,142,,,,,,,,,,,3.00E-11,ruditapes_c5847,,,,,,, comp141964_c0_seq1,2173,36.3553,0.36287074,50,35,,6.00E-114,Q32KV4,Cytoplasmic dynein 2 light intermediate chain 1,Cytoplasmic dynein 2 light intermediate chain 1,GO:0045177; GO:0042384; GO:0035085; GO:0007368; GO:0030286; GO:0030990; GO:0005874; GO:0031512; GO:0003774,apical part of cell; cilium assembly; cilium axoneme; determination of left/right symmetry; dynein complex; intraflagellar transport particle; microtubule; motile primary cilium; motor activity,PF05783;,,,,,,,,,DC2L1_BOVIN,Bos taurus (Bovine),cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368] comp141964_c0_seq2,2160,36.4815,0.37633522,49,94,,7.00E-115,Q32KV4,Cytoplasmic dynein 2 light intermediate chain 1,Cytoplasmic dynein 2 light intermediate chain 1,GO:0045177; GO:0042384; GO:0035085; GO:0007368; GO:0030286; GO:0030990; GO:0005874; GO:0031512; GO:0003774,apical part of cell; cilium assembly; cilium axoneme; determination of left/right symmetry; dynein complex; intraflagellar transport particle; microtubule; motile primary cilium; motor activity,PF05783;,2.00E-80,CHOYP_LOC100372607.1.1,,,,,,,DC2L1_BOVIN,Bos taurus (Bovine),cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368] comp141968_c2_seq1,2045,39.5599,0.43781038,190,2457,,3.00E-49,Q9CZV5,STAGA complex 65 subunit gamma (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like),STAGA complex 65 subunit gamma (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like),GO:0030914; GO:0043966; GO:0004402; GO:0051457; GO:0006355; GO:0003713; GO:0006351,"STAGA complex; histone H3 acetylation; histone acetyltransferase activity; maintenance of protein location in nucleus; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent",PF07524;,2.00E-29,CHOYP_ST65G.1.1,,,,,,,ST65G_MOUSE,Mus musculus (Mouse),"histone H3 acetylation [GO:0043966]; maintenance of protein location in nucleus [GO:0051457]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141968_c2_seq2,1805,38.2825,0.40127172,106,1180,,4.00E-127,P05689,Cathepsin Z (EC 3.4.18.1),Cathepsin Z (EC 3.4.18.1),GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF00112;,8.00E-84,CHOYP_MGC82409.1.1,,,,,,,CATZ_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp141973_c0_seq1,2000,34.1,0.39760014,216,1210,,3.00E-07,Q5ZII6,Protein kish-A (Transmembrane protein 167) (Transmembrane protein 167A),Protein kish-A (Transmembrane protein 167) (Transmembrane protein 167A),GO:0000139; GO:0016021,Golgi membrane; integral to membrane,PF06842;,3.00E-14,CHOYP_contig_041133,,,,,,,KISHA_CHICK,Gallus gallus (Chicken), comp141974_c1_seq2,2100,42.1905,1.03880035,179,5,,7.00E-49,Q5R5L7,Arrestin domain-containing protein 3,Arrestin domain-containing protein 3,GO:0005737,cytoplasm,PF02752;PF00339;,,,,,,,,,ARRD3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp141974_c1_seq4,1873,41.3241,1.00103524,38,0,,7.00E-22,Q5R5L7,Arrestin domain-containing protein 3,Arrestin domain-containing protein 3,GO:0005737,cytoplasm,PF02752;PF00339;,,,,,,,,,ARRD3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp141975_c2_seq1,1681,40.1547,0.71916446,25,16,,,,,,,,,4.00E-74,CHOYP_BRAFLDRAFT_120154.1.2,,,,,,,,, comp141975_c2_seq2,905,43.8674,0.80696455,28,26,,,,,,,,,9.00E-48,CHOYP_BRAFLDRAFT_120154.2.2,,,,,,,,, comp141975_c2_seq3,1196,37.0401,0.4764931,8,19,,2.00E-17,Q6P5L7,Arginine and glutamate-rich protein 1-A,Arginine and glutamate-rich protein 1-A,,,PF15346;,,,,,,,,,ARGLA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp141980_c0_seq2,1208,43.2947,0.37574393,110,296,,1.00E-47,O60140,Uncharacterized protein C18H10.09,Uncharacterized protein C18H10.09,GO:0005737; GO:0008270,cytoplasm; zinc ion binding,PF05495;,2.00E-32,CHOYP_LOC100368927.1.1,,,,,,,YNS9_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp141980_c1_seq3,1432,40.0838,0.52849002,8,12,,3.00E-11,Q941Q3,Zinc finger CCCH domain-containing protein 37 (AtC3H37) (ENHANCER OF AG-4 protein 1),Zinc finger CCCH domain-containing protein 37 (AtC3H37) (ENHANCER OF AG-4 protein 1),GO:0003677; GO:0003723; GO:0001709; GO:0009908; GO:0006397; GO:0046872; GO:0016607; GO:0005634,DNA binding; RNA binding; cell fate determination; flower development; mRNA processing; metal ion binding; nuclear speck; nucleus,PF00642;,,,,,,,,,C3H37_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell fate determination [GO:0001709]; flower development [GO:0009908]; mRNA processing [GO:0006397] comp141981_c0_seq1,1472,38.1793,0.40352498,35,387,,5.00E-95,Q3T186,Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (Fragment),Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (Fragment),GO:0009052; GO:0004751,"pentose-phosphate shunt, non-oxidative branch; ribose-5-phosphate isomerase activity",PF06026;,,,,,,,,,RPIA_BOVIN,Bos taurus (Bovine),"pentose-phosphate shunt, non-oxidative branch [GO:0009052]" comp141981_c0_seq2,1488,38.2392,0.41582694,145,363,,5.00E-95,Q3T186,Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (Fragment),Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (Fragment),GO:0009052; GO:0004751,"pentose-phosphate shunt, non-oxidative branch; ribose-5-phosphate isomerase activity",PF06026;,,,9.00E-17,ruditapes_c9490,,,,,RPIA_BOVIN,Bos taurus (Bovine),"pentose-phosphate shunt, non-oxidative branch [GO:0009052]" comp141981_c0_seq3,758,43.5356,0.69699651,4,181,,,,,,,,,2.00E-11,CHOYP_LOC100165829.1.1,,,,,,,,, comp141983_c0_seq2,3444,42.3055,0.3898255,253,327,,0,Q6ZQ89,E3 ubiquitin-protein ligase MARCH6 (EC 6.3.2.-) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI),E3 ubiquitin-protein ligase MARCH6 (EC 6.3.2.-) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI),GO:0030176; GO:0070936; GO:0004842; GO:0008270,integral to endoplasmic reticulum membrane; protein K48-linked ubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,0,CHOYP_MARH6.1.1,,,,,,,MARH6_MOUSE,Mus musculus (Mouse),proteasomal protein catabolic process [GO:0010498]; protein K48-linked ubiquitination [GO:0070936] comp141983_c0_seq3,688,44.6221,0.5061371,0,0,,4.00E-27,O60103,ERAD-associated E3 ubiquitin-protein ligase doa10 (EC 6.3.2.-),ERAD-associated E3 ubiquitin-protein ligase doa10 (EC 6.3.2.-),GO:0030433; GO:0030176; GO:0004842; GO:0008270,ER-associated protein catabolic process; integral to endoplasmic reticulum membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12906;,,,,,,,,,DOA10_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567] comp141985_c0_seq1,2282,42.901,0.45734709,0,0,,,,,,,,,1.00E-20,CHOYP_FUTSC.3.4,,,,,,,,, comp141985_c0_seq4,4088,42.6614,0.45173529,58,17,,,,,,,,,2.00E-27,CHOYP_SRRM2.1.1,,,,,,,,, comp141987_c0_seq1,1259,42.9706,0.56243758,154,1275,,4.00E-100,Q9D8Z1,Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50),Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50),GO:0003723; GO:0003824; GO:0005737; GO:0006355; GO:0005667; GO:0006351,"RNA binding; catalytic activity; cytoplasm; regulation of transcription, DNA-dependent; transcription factor complex; transcription, DNA-dependent",PF10469;PF00013;,4.00E-16,CHOYP_ASCC1.1.1,3.00E-110,ruditapes_c11270,,,,,ASCC1_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp141988_c0_seq1,2902,40.1103,0.36897745,35,65,,0,Q07598,Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (Fragment),Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (Fragment),GO:0006869; GO:0005739; GO:0005777; GO:0033814; GO:0032934,lipid transport; mitochondrion; peroxisome; propanoyl-CoA C-acyltransferase activity; sterol binding,PF02036;PF02803;PF00108;,0,CHOYP_KS6A1.1.1,,,,,,,NLTP_CHICK,Gallus gallus (Chicken),cholesterol transport [GO:0030301]; phospholipid transport [GO:0015914]; steroid biosynthetic process [GO:0006694] comp141988_c0_seq2,2930,39.9659,0.36808621,16,432,,3.00E-64,O26884,Uncharacterized protein MTH_793,Uncharacterized protein MTH_793,GO:0016747,"transferase activity, transferring acyl groups other than amino-acyl groups",PF02803;PF00108;,,,,,,,,,Y793_METTH,Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum),metabolic process [GO:0008152] comp141991_c0_seq1,2661,37.392,0.39786773,131,192,,3.00E-40,Q96AN5,Transmembrane protein 143,Transmembrane protein 143,GO:0016021; GO:0005739,integral to membrane; mitochondrion,PF12576;,,,,,,,,,TM143_HUMAN,Homo sapiens (Human), comp141991_c0_seq2,1673,35.0867,0.46059448,27,68,,3.00E-07,Q96AN5,Transmembrane protein 143,Transmembrane protein 143,GO:0016021; GO:0005739,integral to membrane; mitochondrion,PF12576;,,,,,,,,,TM143_HUMAN,Homo sapiens (Human), comp141992_c1_seq1,1299,42.9561,0.74590903,187,732,,2.00E-10,E3RPB1,Tethering factor for nuclear proteasome sts1,Tethering factor for nuclear proteasome sts1,GO:0005737; GO:0005634; GO:0071630; GO:0031144; GO:0015031,cytoplasm; nucleus; nucleus-associated proteasomal ubiquitin-dependent protein catabolic process; proteasome localization; protein transport,PF08559;,3.00E-18,CHOYP_ISCW_ISCW022189.1.1,,,,,,,STS1_PYRTT,Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres),nucleus-associated proteasomal ubiquitin-dependent protein catabolic process [GO:0071630]; proteasome localization [GO:0031144]; protein transport [GO:0015031] comp141993_c0_seq1,4603,41.4295,0.42039484,1960,6773,,0,Q15393,Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130),Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130),GO:0005689; GO:0071013; GO:0000398; GO:0003676; GO:0005654; GO:0006461; GO:0030532,"U12-type spliceosomal complex; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleic acid binding; nucleoplasm; protein complex assembly; small nuclear ribonucleoprotein complex",PF03178;,0,CHOYP_SF3B3.1.1,,,,,,,SF3B3_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of protein catabolic process [GO:0042177]; protein complex assembly [GO:0006461]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" comp141994_c0_seq1,2800,41.8214,0.4984219,259,1249,,0,Q704S8,Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT),Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT),GO:0004092; GO:0005783; GO:0006631; GO:0005743; GO:0005739; GO:0005777; GO:0006810,carnitine O-acetyltransferase activity; endoplasmic reticulum; fatty acid metabolic process; mitochondrial inner membrane; mitochondrion; peroxisome; transport,PF00755;,6.00E-31,CHOYP_BRAFLDRAFT_83552.1.1,,,,,,,CACP_RAT,Rattus norvegicus (Rat),fatty acid metabolic process [GO:0006631]; transport [GO:0006810] comp141995_c0_seq8,882,30.3855,0.9879733,4,13,,,,,,,,,,,4.00E-12,ruditapes_c22035,,,,,,, comp141995_c2_seq1,894,37.2483,0.47350978,199,1686,,1.00E-62,Q6IPR3,tRNA wybutosine-synthesizing protein 3 homolog (EC 2.1.1.282) (tRNA-yW-synthesizing protein 3),tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase),GO:0008168; GO:0008033,methyltransferase activity; tRNA processing,PF02676;,,,,,,,,,TYW3_HUMAN,Homo sapiens (Human),tRNA processing [GO:0008033] comp141997_c0_seq1,3262,42.3666,0.45556774,198,1874,,2.00E-141,Q28C44,CWF19-like protein 2,CWF19-like protein 2,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF04677;PF04676;,2.00E-95,CHOYP_LOC100366505.1.1,3.00E-14,ruditapes_c22311,,,,,C19L2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp141998_c0_seq1,797,41.4053,0.55699731,1170,8173,,,,,,,,,5.00E-19,CHOYP_RN45S.4.5,,,,,,,,, comp141999_c0_seq2,2433,41.1426,0.46813327,14,14,,1.00E-138,Q86Y56,HEAT repeat-containing protein 2,"Dynein assembly factor 5, axonemal (HEAT repeat-containing protein 2)",GO:0005737,cytoplasm,PF02985;,,,,,,,,,HEAT2_HUMAN,Homo sapiens (Human),cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158] comp141999_c0_seq3,1657,41.4001,0.47921944,1,0,,,,,,,,,7.00E-78,CHOYP_BRAFLDRAFT_64948.1.1,,,,,,,,, comp142001_c0_seq4,1415,40.9187,0.45748497,16,161,,1.00E-77,Q3UDR8,"Protein YIPF3 (Killer lineage protein 1) (YIP1 family member 3) [Cleaved into: Protein YIPF3, N-terminally processed]","Protein YIPF3 (Killer lineage protein 1) (YIP1 family member 3) [Cleaved into: Protein YIPF3, N-terminally processed]",GO:0005794; GO:0030154; GO:0016021; GO:0005886; GO:0030133,Golgi apparatus; cell differentiation; integral to membrane; plasma membrane; transport vesicle,,7.00E-71,CHOYP_BRAFLDRAFT_215782.1.1,,,,,,,YIPF3_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154] comp142002_c0_seq1,3116,40.0193,0.57543325,0,0,,6.00E-107,Q02395,Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (mPCl2) (Zinc-regulated factor 1) (ZiRF1),Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (mPCl2) (Zinc-regulated factor 1) (ZiRF1),GO:0003677; GO:0016568; GO:0005737; GO:0035064; GO:0061086; GO:0000122; GO:0005634; GO:0061087; GO:0045944; GO:0007379; GO:0019827; GO:0008270,DNA binding; chromatin modification; cytoplasm; methylated histone residue binding; negative regulation of histone H3-K27 methylation; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of histone H3-K27 methylation; positive regulation of transcription from RNA polymerase II promoter; segment specification; stem cell maintenance; zinc ion binding,PF14061;PF00628;,5.00E-51,CHOYP_LOC590080.1.1,,,,,,,MTF2_MOUSE,Mus musculus (Mouse),chromatin modification [GO:0016568]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] comp142002_c0_seq4,2910,40.1031,0.56283508,6,0,,6.00E-107,Q5R7T9,Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2),Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2),GO:0003677; GO:0035098; GO:0016568; GO:0005737; GO:0035064; GO:0061086; GO:0000122; GO:0061087; GO:0045944; GO:0007379; GO:0019827; GO:0008270,DNA binding; ESC/E(Z) complex; chromatin modification; cytoplasm; methylated histone residue binding; negative regulation of histone H3-K27 methylation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone H3-K27 methylation; positive regulation of transcription from RNA polymerase II promoter; segment specification; stem cell maintenance; zinc ion binding,PF14061;PF00628;,5.00E-51,CHOYP_LOC590080.1.1,,,,,,,MTF2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),chromatin modification [GO:0016568]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] comp142004_c1_seq1,1783,39.9327,0.54960836,11,355,,0,Q6AYS4,Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2),Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2),GO:0004560; GO:0005975; GO:0005576; GO:0042806; GO:0006004; GO:0005764,alpha-L-fucosidase activity; carbohydrate metabolic process; extracellular region; fucose binding; fucose metabolic process; lysosome,PF01120;PF16757;,3.00E-101,CHOYP_LOC100367436.1.1,,,,,,,FUCO2_RAT,Rattus norvegicus (Rat),carbohydrate metabolic process [GO:0005975]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]; regulation of entry of bacterium into host cell [GO:2000535]; response to bacterium [GO:0009617] comp142004_c1_seq2,2657,38.615,0.45505913,3,86,,0,C3YWU0,Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),GO:0004560; GO:0005576; GO:0006004,alpha-L-fucosidase activity; extracellular region; fucose metabolic process,PF01120;PF16757;,3.00E-72,CHOYP_FUCO2.1.1,,,,,,,FUCO_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),fucose metabolic process [GO:0006004] comp142004_c1_seq3,1775,38.1408,0.43647102,0,20,,3.00E-179,Q2KIM0,Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1),Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1),GO:0004560; GO:0042806; GO:0006004; GO:0005764,alpha-L-fucosidase activity; fucose binding; fucose metabolic process; lysosome,PF01120;PF16757;,6.00E-130,CHOYP_LOC592142.7.9,,,,,,,FUCO_BOVIN,Bos taurus (Bovine),fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] comp142004_c1_seq4,2649,37.3726,0.36916552,42,383,,0,C3YWU0,Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),GO:0004560; GO:0005576; GO:0006004,alpha-L-fucosidase activity; extracellular region; fucose metabolic process,PF01120;PF16757;,9.00E-149,CHOYP_FUCO.2.2,,,,,,,FUCO_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),fucose metabolic process [GO:0006004] comp142005_c0_seq4,902,43.7916,0.30986734,7,66,,1.00E-06,Q4R3B7,Schlafen-like protein 1,Schlafen-like protein 1,GO:0005524,ATP binding,PF04326;,,,,,,,,,SLNL1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp142012_c0_seq5,274,36.1314,0.92515951,2,15,,1.00E-10,Q16981,Neuronal calcium sensor 1 (NCS-1) (Aplycalcin),Neuronal calcium sensor 1 (NCS-1) (Aplycalcin),GO:0005509,calcium ion binding,PF00036;PF13499;,,,,,,,,,APLC_APLCA,Aplysia californica (California sea hare), comp142014_c1_seq2,2216,35.8755,0.49112635,0,0,,,,,,,,,6.00E-49,CHOYP_LOC583012.1.1,,,,,,,,, comp142014_c1_seq3,4994,36.4437,0.52594795,458,26,,6.00E-89,Q14AW5,Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7),Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7),GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF01189;,,,,,,,,,NSUN7_MOUSE,Mus musculus (Mouse),sperm mitochondrion organization [GO:0030382]; sperm motility [GO:0030317] comp142015_c0_seq2,2732,39.6779,0.3106934,79,423,,9.00E-158,Q8IZ69,tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein),tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein),GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0000166,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; nucleotide binding,PF05958;,,,,,,,,,TRM2A_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp142015_c0_seq3,1175,37.2766,0.41789328,0,6,,8.00E-38,Q8IZ69,tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein),tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein),GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0000166,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; nucleotide binding,PF05958;,,,,,,,,,TRM2A_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp142016_c3_seq1,3771,41.4214,0.52200217,806,1706,,0,P23378,"Glycine dehydrogenase [decarboxylating], mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase)","Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))",GO:0009055; GO:0006546; GO:0004375; GO:0016829; GO:0005739; GO:0030170,electron carrier activity; glycine catabolic process; glycine dehydrogenase (decarboxylating) activity; lyase activity; mitochondrion; pyridoxal phosphate binding,PF01212;PF02347;,0,CHOYP_GCSP.1.1,,,,,,,GCSP_HUMAN,Homo sapiens (Human),glycine catabolic process [GO:0006546]; glycine decarboxylation via glycine cleavage system [GO:0019464]; glyoxylate metabolic process [GO:0046487] comp142021_c0_seq1,4170,43.5971,0.51631397,0,0,,1.00E-38,Q15424,Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein),Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein),GO:0003723; GO:0003682; GO:0006325; GO:0001047; GO:0003690; GO:0040007; GO:0042445; GO:0030520; GO:0000166; GO:0005634; GO:0045944; GO:0006351,"RNA binding; chromatin binding; chromatin organization; core promoter binding; double-stranded DNA binding; growth; hormone metabolic process; intracellular estrogen receptor signaling pathway; nucleotide binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00076;PF02037;,,,,,,,,,SAFB1_HUMAN,Homo sapiens (Human),"chromatin organization [GO:0006325]; growth [GO:0040007]; hormone metabolic process [GO:0042445]; intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mRNA processing [GO:0050684]; transcription, DNA-templated [GO:0006351]" comp142021_c0_seq2,3482,43.7967,0.56788665,0,0,,7.00E-37,O88453,Scaffold attachment factor B1 (SAF-B) (SAF-B1),Scaffold attachment factor B1 (SAF-B) (SAF-B1),GO:0003723; GO:0000166; GO:0005634; GO:0050684; GO:0006357; GO:0043565; GO:0006351,"RNA binding; nucleotide binding; nucleus; regulation of mRNA processing; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription, DNA-dependent",PF00076;PF02037;,4.00E-40,CHOYP_SAFB2.2.3,,,,,,,SAFB1_RAT,Rattus norvegicus (Rat),"regulation of mRNA processing [GO:0050684]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142021_c0_seq3,3494,43.7321,0.56766507,0,0,,7.00E-37,O88453,Scaffold attachment factor B1 (SAF-B) (SAF-B1),Scaffold attachment factor B1 (SAF-B) (SAF-B1),GO:0003723; GO:0000166; GO:0005634; GO:0050684; GO:0006357; GO:0043565; GO:0006351,"RNA binding; nucleotide binding; nucleus; regulation of mRNA processing; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription, DNA-dependent",PF00076;PF02037;,,,,,,,,,SAFB1_RAT,Rattus norvegicus (Rat),"regulation of mRNA processing [GO:0050684]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142021_c0_seq4,4158,43.6508,0.51648494,0,0,,1.00E-38,Q15424,Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein),Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein),GO:0003723; GO:0003682; GO:0006325; GO:0001047; GO:0003690; GO:0040007; GO:0042445; GO:0030520; GO:0000166; GO:0005634; GO:0045944; GO:0006351,"RNA binding; chromatin binding; chromatin organization; core promoter binding; double-stranded DNA binding; growth; hormone metabolic process; intracellular estrogen receptor signaling pathway; nucleotide binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00076;PF02037;,5.00E-40,CHOYP_SAFB2.2.3,,,,,,,SAFB1_HUMAN,Homo sapiens (Human),"chromatin organization [GO:0006325]; growth [GO:0040007]; hormone metabolic process [GO:0042445]; intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mRNA processing [GO:0050684]; transcription, DNA-templated [GO:0006351]" comp142022_c0_seq1,5749,42.3552,0.36874502,1559,5401,,0,Q9Z0W3,Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Gene trap locus 1-13 protein) (GTL-13) (Nucleoporin Nup160),Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Gene trap locus 1-13 protein) (GTL-13) (Nucleoporin Nup160),GO:0000776; GO:0006406; GO:0031080; GO:0005487; GO:0015031,kinetochore; mRNA export from nucleus; nuclear pore outer ring; nucleocytoplasmic transporter activity; protein transport,,5.00E-61,CHOYP_NU160.1.1,,,,,,,NU160_MOUSE,Mus musculus (Mouse),mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031] comp142025_c1_seq2,1433,34.9616,0.85370918,217,441,,5.00E-27,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp142029_c0_seq1,5339,43.791,0.77070337,62,16,,1.00E-76,Q9P2F6,Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),GO:0005096; GO:0005829; GO:0005543; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; phospholipid binding; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00620;,1.00E-49,CHOYP_NEMVEDRAFT_V1G209966.1.1,,,,,,,RHG20_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp142029_c0_seq3,4115,44.034,0.81310946,0,0,,2.00E-77,Q9P2F6,Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20),GO:0005096; GO:0005829; GO:0005543; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; phospholipid binding; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00620;,5.00E-46,CHOYP_LOC582570.1.1,,,,,,,RHG20_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp142031_c0_seq3,2139,42.964,0.42569324,56,203,,4.00E-123,Q9H8Y8,Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59),Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59),GO:0000139; GO:0000278; GO:0006996,Golgi membrane; mitotic cell cycle; organelle organization,PF04495;,8.00E-123,CHOYP_BRAFLDRAFT_118294.1.2,,,,,,,GORS2_HUMAN,Homo sapiens (Human),organelle organization [GO:0006996] comp142032_c0_seq1,2003,39.5906,0.38299834,218,333,,0,Q8N5T2,TBC1 domain family member 19,TBC1 domain family member 19,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,0,CHOYP_TBC19.1.1,,,,,,,TBC19_HUMAN,Homo sapiens (Human), comp142036_c0_seq1,1657,38.9861,0.45728937,13,72,,4.00E-31,Q6IQ49,Protein SDE2 homolog,Protein SDE2 homolog,,,PF13019;,6.00E-47,CHOYP_BRAFLDRAFT_120767.1.1,,,,,,,SDE2_HUMAN,Homo sapiens (Human), comp142036_c0_seq2,1902,37.5394,0.42750333,66,110,,7.00E-13,Q12874,Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61),Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61),GO:0071013; GO:0000389; GO:0016607; GO:0003676; GO:0005654; GO:0008270,catalytic step 2 spliceosome; mRNA 3'-splice site recognition; nuclear speck; nucleic acid binding; nucleoplasm; zinc ion binding,PF11931;PF16837;PF12108;,,,,,,,,,SF3A3_HUMAN,Homo sapiens (Human),"mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" comp142036_c0_seq3,336,36.9048,0.30089552,23,64,,,,,,,,,2.00E-13,CHOYP_LOC100721364.1.1,,,,,,,,, comp142036_c1_seq1,1515,42.1782,0.52591955,41,78,,9.00E-159,Q14692,Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog),Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog),GO:0005524; GO:0005730; GO:0042255,ATP binding; nucleolus; ribosome assembly,PF08142;PF04950;,1.00E-168,CHOYP_BMS1.1.1,,,,,,,BMS1_HUMAN,Homo sapiens (Human),"endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]" comp142036_c1_seq2,774,43.4109,0.50136656,0,0,,6.00E-06,Q5XGY1,Pre-rRNA-processing protein TSR1 homolog,Pre-rRNA-processing protein TSR1 homolog,GO:0005730; GO:0042255,nucleolus; ribosome assembly,PF08142;PF04950;,,,,,,,,,TSR1_XENLA,Xenopus laevis (African clawed frog),ribosome assembly [GO:0042255] comp142037_c1_seq5,2165,43.6952,0.49561225,3,0,,,,,,,,,0,CHOYP_LOC100533349.3.5,,,,,,,,, comp142040_c0_seq2,3851,41.7554,0.49258315,1,0,,,,,,,,,2.00E-33,CHOYP_RS8.12.14,,,,,,,,, comp142040_c0_seq4,2022,40.5045,0.34411041,0,0,,,,,,,,,,,1.00E-34,ruditapes_c17587,,,,,,, comp142040_c0_seq5,3869,41.7162,0.49702422,0,0,,6.00E-20,Q8N3X1,Formin-binding protein 4 (Formin-binding protein 30),Formin-binding protein 4 (Formin-binding protein 30),GO:0005634,nucleus,PF00397;,2.00E-33,CHOYP_RS8.12.14,,,,,,,FNBP4_HUMAN,Homo sapiens (Human), comp142041_c0_seq1,1614,41.3259,1.02617907,2,65,,8.00E-24,Q8NFM4,Adenylate cyclase type 4 (EC 4.6.1.1) (ATP pyrophosphate-lyase 4) (Adenylate cyclase type IV) (Adenylyl cyclase 4),Adenylate cyclase type 4 (EC 4.6.1.1) (ATP pyrophosphate-lyase 4) (Adenylate cyclase type IV) (Adenylyl cyclase 4),GO:0005524; GO:0007202; GO:0034199; GO:0004016; GO:0007189; GO:0007193; GO:0071377; GO:0005737; GO:0030425; GO:0006112; GO:0007173; GO:0008543; GO:0045087; GO:0016021; GO:0035556; GO:0046872; GO:0048011; GO:0005886; GO:0007268; GO:0055085; GO:0006833,ATP binding; activation of phospholipase C activity; activation of protein kinase A activity; adenylate cyclase activity; adenylate cyclase-activating G-protein coupled receptor signaling pathway; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; cellular response to glucagon stimulus; cytoplasm; dendrite; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; integral to membrane; intracellular signal transduction; metal ion binding; neurotrophin TRK receptor signaling pathway; plasma membrane; synaptic transmission; transmembrane transport; water transport,PF16214;PF06327;PF00211;,3.00E-25,CHOYP_LOC100748515.1.1,,,,,,,ADCY4_HUMAN,Homo sapiens (Human),activation of adenylate cyclase activity [GO:0007190]; activation of protein kinase A activity [GO:0034199]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to glucagon stimulus [GO:0071377]; renal water homeostasis [GO:0003091] comp142041_c0_seq2,1632,41.299,1.00359875,2,37,,4.00E-122,P18910,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0005525; GO:0007166; GO:0042417; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0048662; GO:0017046; GO:0005886; GO:0030828; GO:0004672; GO:0019901; GO:0007168; GO:0050880,ATP binding; GTP binding; cell surface receptor signaling pathway; dopamine metabolic process; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of smooth muscle cell proliferation; peptide hormone binding; plasma membrane; positive regulation of cGMP biosynthetic process; protein kinase activity; protein kinase binding; receptor guanylyl cyclase signaling pathway; regulation of blood vessel size,PF01094;PF00211;PF07714;,3.00E-51,CHOYP_ANPRB.1.2,,,,,,,ANPRA_RAT,Rattus norvegicus (Rat),cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880] comp142041_c0_seq3,395,47.8481,0.84312508,0,0,,1.00E-12,Q54H45,Probable serine/threonine-protein kinase drkB (EC 2.7.11.1) (Receptor-like kinase 2) (Receptor-like kinase B) (Vesicle-associated receptor tyrosine kinase-like protein 2),Probable serine/threonine-protein kinase drkB (EC 2.7.11.1) (Receptor-like kinase 2) (Receptor-like kinase B) (Vesicle-associated receptor tyrosine kinase-like protein 2),GO:0005524; GO:0016021; GO:0004674,ATP binding; integral to membrane; protein serine/threonine kinase activity,PF07714;,,,,,,,,,DRKB_DICDI,Dictyostelium discoideum (Slime mold), comp142041_c0_seq5,354,47.7401,0.74643152,1,0,,3.00E-33,P11528,Resact receptor (EC 4.6.1.2) (Guanylate cyclase),Resact receptor (EC 4.6.1.2) (Guanylate cyclase),GO:0005524; GO:0005525; GO:0004383; GO:0016021; GO:0004672,ATP binding; GTP binding; guanylate cyclase activity; integral to membrane; protein kinase activity,PF01094;PF07701;PF07714;,,,,,,,,,GCY_ARBPU,Arbacia punctulata (Punctuate sea urchin), comp142042_c0_seq1,3213,38.5621,0.54434838,55,321,,8.00E-27,Q9DBB9,Carboxypeptidase N subunit 2 (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N large subunit) (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N regulatory subunit),Carboxypeptidase N subunit 2 (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N large subunit) (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N regulatory subunit),GO:0005576,extracellular region,PF13855;,,,,,,,,,CPN2_MOUSE,Mus musculus (Mouse), comp142042_c0_seq2,3194,38.7289,0.54288446,69,0,,1.00E-37,Q8R5M3,Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid) (rLib),Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid) (rLib),GO:0007154; GO:0016021; GO:0005622,cell communication; integral to membrane; intracellular,PF00560;PF13855;,,,,,,,,,LRC15_RAT,Rattus norvegicus (Rat),cell communication [GO:0007154]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469] comp142044_c2_seq10,1581,36.1796,0.43398691,0,0,,,,,,,,,2.00E-15,CHOYP_LOC100892236.4.7,,,,,,,,, comp142044_c2_seq12,1610,36.3354,0.40354764,0,0,,,,,,,,,4.00E-18,CHOYP_LOC100007585.5.7,,,,,,,,, comp142044_c2_seq14,788,41.3706,0.51801729,0,0,,,,,,,,,9.00E-16,CHOYP_LOC100892236.4.7,,,,,,,,, comp142044_c2_seq15,2177,35.3238,0.37965954,0,0,,,,,,,,,2.00E-11,CHOYP_LOC100890720.1.1,,,,,,,,, comp142044_c2_seq16,2164,35.1664,0.39993472,0,0,,,,,,,,,5.00E-18,CHOYP_LOC100007585.5.7,,,,,,,,, comp142044_c2_seq20,1635,36.6361,0.40664347,0,0,,,,,,,,,2.00E-15,CHOYP_LOC100892236.4.7,,,,,,,,, comp142044_c2_seq21,2240,35.2232,0.41461618,0,0,,,,,,,,,5.00E-18,CHOYP_LOC100007585.5.7,,,,,,,,, comp142044_c2_seq8,525,41.9048,0.45282533,0,6,,,,,,,,,1.00E-18,CHOYP_LOC100007585.5.7,,,,,,,,, comp142045_c1_seq1,2912,37.9464,0.74710969,0,0,,5.00E-167,Q9BYP7,Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3),Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3),GO:0005524; GO:0005912; GO:0005737; GO:0007243; GO:0043066; GO:0051928; GO:0090004; GO:0010800; GO:2000688; GO:2000682; GO:2000651; GO:0010765; GO:0046777; GO:0004674; GO:2000021; GO:0005923,ATP binding; adherens junction; cytoplasm; intracellular protein kinase cascade; negative regulation of apoptotic process; positive regulation of calcium ion transport; positive regulation of establishment of protein localization to plasma membrane; positive regulation of peptidyl-threonine phosphorylation; positive regulation of rubidium ion transmembrane transporter activity; positive regulation of rubidium ion transport; positive regulation of sodium ion transmembrane transporter activity; positive regulation of sodium ion transport; protein autophosphorylation; protein serine/threonine kinase activity; regulation of ion homeostasis; tight junction,PF12202;PF00069;,0,CHOYP_WNK2.2.2,,,,,,,WNK3_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of pancreatic juice secretion [GO:0090188]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of rubidium ion transmembrane transporter activity [GO:2000688]; positive regulation of rubidium ion transport [GO:2000682]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of ion homeostasis [GO:2000021] comp142045_c1_seq8,3001,38.6871,0.70672015,0,0,,4.00E-170,Q9BYP7,Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3),Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3),GO:0005524; GO:0005912; GO:0005737; GO:0007243; GO:0043066; GO:0051928; GO:0090004; GO:0010800; GO:2000688; GO:2000682; GO:2000651; GO:0010765; GO:0046777; GO:0004674; GO:2000021; GO:0005923,ATP binding; adherens junction; cytoplasm; intracellular protein kinase cascade; negative regulation of apoptotic process; positive regulation of calcium ion transport; positive regulation of establishment of protein localization to plasma membrane; positive regulation of peptidyl-threonine phosphorylation; positive regulation of rubidium ion transmembrane transporter activity; positive regulation of rubidium ion transport; positive regulation of sodium ion transmembrane transporter activity; positive regulation of sodium ion transport; protein autophosphorylation; protein serine/threonine kinase activity; regulation of ion homeostasis; tight junction,PF12202;PF00069;,,,,,,,,,WNK3_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of pancreatic juice secretion [GO:0090188]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of rubidium ion transmembrane transporter activity [GO:2000688]; positive regulation of rubidium ion transport [GO:2000682]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of ion homeostasis [GO:2000021] comp142045_c1_seq9,1042,40.7869,0.70750303,0,0,,5.00E-30,Q8TDX7,Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7),Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7),GO:0005524; GO:0000910; GO:0005737; GO:0046872; GO:0005874; GO:0005815; GO:0005634; GO:0004674; GO:0007346; GO:0051225; GO:0000922,ATP binding; cytokinesis; cytoplasm; metal ion binding; microtubule; microtubule organizing center; nucleus; protein serine/threonine kinase activity; regulation of mitotic cell cycle; spindle assembly; spindle pole,PF00069;,8.00E-176,CHOYP_WNK2.2.2,,,,,,,NEK7_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] comp142046_c0_seq2,3421,36.6559,0.92392265,0,67,,,,,,,,,,,9.00E-40,ruditapes_c8877,,,,,,, comp142047_c0_seq1,2339,39.2048,0.41914784,589,2291,,0,Q99MN1,Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS),Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS),GO:0005524; GO:0004824; GO:0006430; GO:0046872; GO:0005739; GO:0003676,ATP binding; lysine-tRNA ligase activity; lysyl-tRNA aminoacylation; metal ion binding; mitochondrion; nucleic acid binding,PF00152;PF01336;,0,CHOYP_LOC100114247.1.1,,,,,,,SYK_MOUSE,Mus musculus (Mouse),lysyl-tRNA aminoacylation [GO:0006430] comp142049_c0_seq1,1928,36.7739,0.44588726,206,2470,,6.00E-30,Q9R1Q9,V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein C7-1) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1),V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein C7-1) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1),GO:0005524; GO:0015991; GO:0016021; GO:0046933; GO:0046961; GO:0033180; GO:0005774,"ATP binding; ATP hydrolysis coupled proton transport; integral to membrane; proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATPase activity, rotational mechanism; proton-transporting V-type ATPase, V1 domain; vacuolar membrane",PF05827;,9.00E-14,CHOYP_ATP6AP1.1.1,6.00E-39,ruditapes_c10659,,,,,VAS1_MOUSE,Mus musculus (Mouse),ATP hydrolysis coupled proton transport [GO:0015991]; establishment of organelle localization [GO:0051656]; pH reduction [GO:0045851]; positive regulation of bone resorption [GO:0045780]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoclast development [GO:2001206] comp142051_c0_seq1,2047,41.9638,0.87810047,0,0,,0,Q7YQC6,Heat shock 70 kDa protein 1,Heat shock 70 kDa protein 1,GO:0005524; GO:0005737; GO:0006950; GO:0030529,ATP binding; cytoplasm; response to stress; ribonucleoprotein complex,PF00012;,0,CHOYP_HSP74.1.1,,,,,,,HSP71_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp142051_c0_seq2,2406,39.3599,0.89860063,0,0,,0,Q91233,Heat shock 70 kDa protein (HSP70),Heat shock 70 kDa protein (HSP70),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,0,CHOYP_HSC70.1.1,,,,,,,HSP70_ONCTS,Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha), comp142051_c0_seq3,3053,37.3076,0.9284305,93,75,,0,P41827,Heat shock protein 70 B2,Heat shock protein 70 B2,GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,,,,,,,,,HSP74_ANOAL,Anopheles albimanus (New world malaria mosquito), comp142051_c0_seq4,1099,43.5851,0.9826942,23,26,,8.00E-58,Q4UKL3,Chaperone protein HscA homolog,Chaperone protein HscA homolog,GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,4.00E-148,CHOYP_HSP7D.3.3,,,,,,,HSCA_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi), comp142051_c0_seq6,2694,38.9755,0.9190567,0,0,,0,Q91233,Heat shock 70 kDa protein (HSP70),Heat shock 70 kDa protein (HSP70),GO:0005524; GO:0006950,ATP binding; response to stress,PF00012;,0,CHOYP_HSP74.1.1,1.00E-24,ruditapes2_c147,,,,,HSP70_ONCTS,Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha), comp142052_c0_seq1,2520,35.3571,0.55439094,343,4174,,2.00E-102,Q5R4R6,Signal recognition particle 54 kDa protein (SRP54),Signal recognition particle 54 kDa protein (SRP54),GO:0008312; GO:0019003; GO:0005525; GO:0006184; GO:0003924; GO:0006614; GO:0008144; GO:0030942; GO:0016607; GO:0005634; GO:0045047; GO:0042493; GO:0005786,"7S RNA binding; GDP binding; GTP binding; GTP catabolic process; GTPase activity; SRP-dependent cotranslational protein targeting to membrane; drug binding; endoplasmic reticulum signal peptide binding; nuclear speck; nucleus; protein targeting to ER; response to drug; signal recognition particle, endoplasmic reticulum targeting",PF00448;PF02881;PF02978;,3.00E-166,CHOYP_SRP54.1.2,,,,,,,SRP54_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein targeting to ER [GO:0045047]; response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp142052_c0_seq2,389,38.8175,0.49474774,4,27,,2.00E-34,P14576,Signal recognition particle 54 kDa protein (SRP54),Signal recognition particle 54 kDa protein (SRP54),GO:0008312; GO:0005525; GO:0006184; GO:0003924; GO:0006614; GO:0016607; GO:0005786,"7S RNA binding; GTP binding; GTP catabolic process; GTPase activity; SRP-dependent cotranslational protein targeting to membrane; nuclear speck; signal recognition particle, endoplasmic reticulum targeting",PF00448;PF02881;PF02978;,2.00E-39,CHOYP_SRP54.2.2,,,,,,,SRP54_MOUSE,Mus musculus (Mouse),SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp142056_c0_seq1,2884,37.9681,0.44392816,376,1568,,0,Q3ZBH0,T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta),T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta),GO:0005524; GO:0007339; GO:0051131; GO:0005832; GO:0005874; GO:0005634; GO:0006457; GO:0002199,ATP binding; binding of sperm to zona pellucida; chaperone-mediated protein complex assembly; chaperonin-containing T-complex; microtubule; nucleus; protein folding; zona pellucida receptor complex,PF00118;,0,CHOYP_TCPB.1.1,1.00E-19,ruditapes2_c481,,,,,TCPB_BOVIN,Bos taurus (Bovine),binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]; toxin transport [GO:1901998] comp142056_c0_seq2,2905,37.6936,0.43671791,291,2474,,0,Q3ZBH0,T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta),T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta),GO:0005524; GO:0007339; GO:0051131; GO:0005832; GO:0005874; GO:0005634; GO:0006457; GO:0002199,ATP binding; binding of sperm to zona pellucida; chaperone-mediated protein complex assembly; chaperonin-containing T-complex; microtubule; nucleus; protein folding; zona pellucida receptor complex,PF00118;,,,0,ruditapes_c17113,,,,,TCPB_BOVIN,Bos taurus (Bovine),binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]; toxin transport [GO:1901998] comp142060_c0_seq1,1050,43.9048,0.58604499,0,0,,1.00E-09,Q6DN14,Multiple C2 and transmembrane domain-containing protein 1,Multiple C2 and transmembrane domain-containing protein 1,GO:0005509; GO:0019722; GO:0016021,calcium ion binding; calcium-mediated signaling; integral to membrane,PF00168;PF08372;,8.00E-138,CHOYP_KPC1.2.2,,,,,,,MCTP1_HUMAN,Homo sapiens (Human),calcium-mediated signaling [GO:0019722] comp142060_c0_seq3,2510,40.9562,0.58948208,55,84,,0,P05696,Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13),Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13),GO:0005524; GO:0007568; GO:0001525; GO:0006915; GO:0004698; GO:0007155; GO:0021955; GO:0005829; GO:0045184; GO:0035556; GO:0007611; GO:0045121; GO:0031966; GO:0005739; GO:0034351; GO:0045822; GO:0017148; GO:0043005; GO:0005634; GO:0018105; GO:0018107; GO:0048471; GO:0005886; GO:0070374; GO:0045766; GO:0010613; GO:0045785; GO:2000707; GO:0010595; GO:0001938; GO:0045921; GO:0031666; GO:0045651; GO:0045931; GO:0048661; GO:0051965; GO:0046777; GO:0043234; GO:0090330; GO:0048259; GO:0046677; GO:0051412; GO:0032355; GO:0045471; GO:0009612; GO:0043434; GO:0000302; GO:0008270,ATP binding; aging; angiogenesis; apoptotic process; calcium-dependent protein kinase C activity; cell adhesion; central nervous system neuron axonogenesis; cytosol; establishment of protein localization; intracellular signal transduction; learning or memory; membrane raft; mitochondrial membrane; mitochondrion; negative regulation of glial cell apoptotic process; negative regulation of heart contraction; negative regulation of translation; neuron projection; nucleus; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; perinuclear region of cytoplasm; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of angiogenesis; positive regulation of cardiac muscle hypertrophy; positive regulation of cell adhesion; positive regulation of dense core granule biogenesis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of exocytosis; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of macrophage differentiation; positive regulation of mitotic cell cycle; positive regulation of smooth muscle cell proliferation; positive regulation of synapse assembly; protein autophosphorylation; protein complex; regulation of platelet aggregation; regulation of receptor-mediated endocytosis; response to antibiotic; response to corticosterone stimulus; response to estradiol stimulus; response to ethanol; response to mechanical stimulus; response to peptide hormone stimulus; response to reactive oxygen species; zinc ion binding,PF00130;PF00168;PF00069;PF00433;,,,,,,,,,KPCA_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636] comp142060_c0_seq5,1961,43.4472,0.60293016,2,0,,0,Q16974,Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I),Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I),GO:0005524; GO:0005737; GO:0035556; GO:0004697; GO:0008270,ATP binding; cytoplasm; intracellular signal transduction; protein kinase C activity; zinc ion binding,PF00130;PF00168;PF00069;PF00433;,0,CHOYP_KPC1.2.2,,,,,,,KPC1_APLCA,Aplysia californica (California sea hare),intracellular signal transduction [GO:0035556] comp142062_c0_seq1,2235,44.2058,1.00194058,0,8,,,,,,,,,2.00E-93,CHOYP_SBP1.1.2,,,,,,,,, comp142062_c0_seq4,1964,46.4358,0.94832728,183,228,,0,Q52KZ7,Selenium-binding protein 1-A,Selenium-binding protein 1-A,GO:0005829; GO:0016020; GO:0005634; GO:0015031; GO:0008430,cytosol; membrane; nucleus; protein transport; selenium binding,PF05694;,3.00E-96,CHOYP_SBP1.1.2,8.00E-82,ruditapes_c1270,,,,,SBP1A_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp142062_c0_seq5,1987,46.15,0.98654425,4,69,,0,Q8VIF7,Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 2),Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 2),GO:0005829; GO:0016020; GO:0005634; GO:0015031; GO:0008430,cytosol; membrane; nucleus; protein transport; selenium binding,PF05694;,,,,,,,,,SBP1_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp142062_c0_seq6,2244,44.1622,0.99154309,30,17,,0,Q52KZ7,Selenium-binding protein 1-A,Selenium-binding protein 1-A,GO:0005829; GO:0016020; GO:0005634; GO:0015031; GO:0008430,cytosol; membrane; nucleus; protein transport; selenium binding,PF05694;,,,9.00E-76,ruditapes2_c3515,,,,,SBP1A_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp142063_c0_seq1,1290,34.4961,0.20885756,110,994,,1.00E-55,Q5VYX0,Renalase (EC 1.4.-.-) (Monoamine oxidase-C) (MAO-C),Renalase (EC 1.6.3.5) (Monoamine oxidase-C) (MAO-C),GO:0005576; GO:0016491,extracellular region; oxidoreductase activity,PF01593;,,,,,,,,,RNLS_HUMAN,Homo sapiens (Human),response to epinephrine [GO:0071871]; response to ischemia [GO:0002931]; response to salt [GO:1902074] comp142065_c0_seq2,626,45.6869,0.81837558,9,4,,8.00E-17,P93823,RING-H2 finger protein ATL1,RING-H2 finger protein ATL1,GO:0016021; GO:0016567; GO:0008270,integral to membrane; protein ubiquitination; zinc ion binding,PF13639;,,,,,,,,,ATL1_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ubiquitination [GO:0016567] comp142065_c1_seq1,1872,42.1474,0.51848107,164,394,,0,Q9BXJ9,"N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100)","N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100)",GO:0008080; GO:0006474; GO:0001525; GO:0030154; GO:0005737; GO:0005634; GO:0045893; GO:0005667; GO:0006351,"N-acetyltransferase activity; N-terminal protein amino acid acetylation; angiogenesis; cell differentiation; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; transcription factor complex; transcription, DNA-dependent",PF12569;PF13181;,0,CHOYP_NAA15.1.1,8.00E-120,ruditapes_c24966,,,,,NAA15_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; negative regulation of apoptotic process [GO:0043066]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; positive regulation of transcription, DNA-templated [GO:0045893]; protein stabilization [GO:0050821]; transcription, DNA-templated [GO:0006351]" comp142066_c0_seq12,884,32.1267,0.7932092,0,0,,2.00E-07,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp142066_c0_seq7,871,32.3766,0.79204828,0,0,,2.00E-07,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp142066_c0_seq8,1656,31.099,0.78119991,5,73,,4.00E-11,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp142068_c2_seq3,369,35.5014,0.34742039,3,0,,1.00E-05,Q9SB51,Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (AtUBP16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (AtUBP16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16),GO:0008283; GO:0008234; GO:0009908; GO:0016021; GO:0048366; GO:0046872; GO:0016579; GO:1901000; GO:0009651; GO:0048364; GO:0004221; GO:0006511,cell proliferation; cysteine-type peptidase activity; flower development; integral to membrane; leaf development; metal ion binding; protein deubiquitination; regulation of response to salt stress; response to salt stress; root development; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;PF01753;,,,,,,,,,UBP16_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell proliferation [GO:0008283]; flower development [GO:0009908]; leaf development [GO:0048366]; protein deubiquitination [GO:0016579]; regulation of response to salt stress [GO:1901000]; response to salt stress [GO:0009651]; root development [GO:0048364]; shoot system development [GO:0048367]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142068_c2_seq4,487,37.7823,0.23396958,0,0,,4.00E-06,Q9FPS4,Ubiquitin carboxyl-terminal hydrolase 23 (EC 3.4.19.12) (Deubiquitinating enzyme 23) (AtUBP23) (Ubiquitin thioesterase 23) (Ubiquitin-specific-processing protease 23),Ubiquitin carboxyl-terminal hydrolase 23 (EC 3.4.19.12) (Deubiquitinating enzyme 23) (AtUBP23) (Ubiquitin thioesterase 23) (Ubiquitin-specific-processing protease 23),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP23_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142068_c2_seq8,466,37.3391,0.25010157,0,0,,4.00E-06,Q9FPS4,Ubiquitin carboxyl-terminal hydrolase 23 (EC 3.4.19.12) (Deubiquitinating enzyme 23) (AtUBP23) (Ubiquitin thioesterase 23) (Ubiquitin-specific-processing protease 23),Ubiquitin carboxyl-terminal hydrolase 23 (EC 3.4.19.12) (Deubiquitinating enzyme 23) (AtUBP23) (Ubiquitin thioesterase 23) (Ubiquitin-specific-processing protease 23),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP23_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142069_c0_seq1,1992,40.1606,0.72226986,20,9,,4.00E-130,Q5BKN4,Septin-2A,Septin-2A,GO:0005525; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0005737; GO:0030496; GO:0007067; GO:0031105; GO:0007224; GO:0005819,GTP binding; cell division; cilium assembly; cilium membrane; cleavage furrow; cytoplasm; midbody; mitosis; septin complex; smoothened signaling pathway; spindle,PF00735;,,,,,,,,,SEP2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; smoothened signaling pathway [GO:0007224] comp142069_c0_seq2,1977,40.0101,0.70728011,34,179,,0,Q5R481,Septin-7,Septin-7,GO:0005525; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0016476; GO:0031105; GO:0005819,GTP binding; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; regulation of embryonic cell shape; septin complex; spindle,PF00735;,0,CHOYP_SEPT7.1.1,,,,,,,SEPT7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476] comp142069_c0_seq3,859,42.4913,0.65640927,0,0,,,,,,,,,1.00E-110,CHOYP_SEPT7.1.1,,,,,,,,, comp142071_c1_seq3,1864,35.1395,0.41734278,2,36,,2.00E-53,Q502K9,Selenoprotein T2,Selenoprotein T2,GO:0045454; GO:0008430,cell redox homeostasis; selenium binding,PF10262;,1.00E-62,CHOYP_LOC755635.1.1,,,,,,,SELT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142075_c0_seq1,4654,43.1457,0.47364102,1343,2917,,0,P52701,DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS-alpha 160 kDa subunit) (p160),DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160),GO:0005524; GO:0008094; GO:0032301; GO:0003682; GO:0003684; GO:0008340; GO:0032137; GO:0008630; GO:0045190; GO:0000710; GO:0035064; GO:0030983; GO:0045910; GO:0000790; GO:0000228; GO:0051096; GO:0007131; GO:0009411; GO:0016446,ATP binding; DNA-dependent ATPase activity; MutSalpha complex; chromatin binding; damaged DNA binding; determination of adult lifespan; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; meiotic mismatch repair; methylated histone residue binding; mismatched DNA binding; negative regulation of DNA recombination; nuclear chromatin; nuclear chromosome; positive regulation of helicase activity; reciprocal meiotic recombination; response to UV; somatic hypermutation of immunoglobulin genes,PF01624;PF05188;PF05192;PF05190;PF00488;PF00855;,0,CHOYP_BRAFLDRAFT_283756.1.1,,,,,,,MSH6_HUMAN,Homo sapiens (Human),determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching [GO:0045830]; reciprocal meiotic recombination [GO:0007131]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; viral process [GO:0016032] comp142075_c0_seq2,1198,44.6578,0.43775131,26,3,,4.00E-24,P54276,DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS-alpha 160 kDa subunit) (p160),DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160),GO:0043531; GO:0005524; GO:0008094; GO:0032301; GO:0003682; GO:0003684; GO:0008340; GO:0000400; GO:0032137; GO:0008630; GO:0045190; GO:0000287; GO:0043570; GO:0000710; GO:0035064; GO:0045910; GO:0000790; GO:0032357; GO:0051096; GO:0007131; GO:0009411; GO:0032138; GO:0032142; GO:0032143; GO:0016446,ADP binding; ATP binding; DNA-dependent ATPase activity; MutSalpha complex; chromatin binding; damaged DNA binding; determination of adult lifespan; four-way junction DNA binding; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; magnesium ion binding; maintenance of DNA repeat elements; meiotic mismatch repair; methylated histone residue binding; negative regulation of DNA recombination; nuclear chromatin; oxidized purine DNA binding; positive regulation of helicase activity; reciprocal meiotic recombination; response to UV; single base insertion or deletion binding; single guanine insertion binding; single thymine insertion binding; somatic hypermutation of immunoglobulin genes,PF01624;PF05188;PF05192;PF05190;PF00488;PF00855;,,,,,,,,,MSH6_MOUSE,Mus musculus (Mouse),determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching [GO:0045830]; reciprocal meiotic recombination [GO:0007131]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447] comp142077_c1_seq1,6265,41.0215,0.39876262,0,0,,3.00E-14,O42287,Intersectin-1,Intersectin-1,GO:0005509; GO:0030054; GO:0006897; GO:0012505; GO:0016020; GO:0043005; GO:0045202,calcium ion binding; cell junction; endocytosis; endomembrane system; membrane; neuron projection; synapse,PF12763;PF00018;PF07653;PF14604;,,,,,,,,,ITSN1_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897] comp142077_c1_seq10,4374,42.0668,0.36752745,0,0,,2.00E-14,O42287,Intersectin-1,Intersectin-1,GO:0005509; GO:0030054; GO:0006897; GO:0012505; GO:0016020; GO:0043005; GO:0045202,calcium ion binding; cell junction; endocytosis; endomembrane system; membrane; neuron projection; synapse,PF12763;PF00018;PF07653;PF14604;,,,,,,,,,ITSN1_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897] comp142077_c1_seq16,829,45.8384,0.48006085,0,0,,2.00E-08,O60504,Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3),Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3),GO:0007155; GO:0031589; GO:0005856; GO:0005829; GO:0005925; GO:0006936; GO:0000122; GO:0005634; GO:0043410; GO:0051496; GO:0005200,cell adhesion; cell-substrate adhesion; cytoskeleton; cytosol; focal adhesion; muscle contraction; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of MAPK cascade; positive regulation of stress fiber assembly; structural constituent of cytoskeleton,PF00018;PF14604;PF02208;,,,,,,,,,VINEX_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; muscle contraction [GO:0006936]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cytoskeleton organization [GO:0051495]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of stress fiber assembly [GO:0051496] comp142077_c1_seq17,3917,42.3538,0.3473455,0,0,,6.00E-08,Q1LYG0,SH3 and PX domain-containing protein 2A,SH3 and PX domain-containing protein 2A,GO:0007154; GO:0030054; GO:0042995; GO:0005737; GO:0035091; GO:0002102; GO:0006801,cell communication; cell junction; cell projection; cytoplasm; phosphatidylinositol binding; podosome; superoxide metabolic process,PF00787;PF00018;PF07653;,,,,,,,,,SPD2A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),neural crest cell migration [GO:0001755]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; posterior lateral line neuromast primordium migration [GO:0048920]; reactive oxygen species metabolic process [GO:0072593]; superoxide metabolic process [GO:0006801] comp142077_c1_seq18,1297,43.3308,0.52990438,0,0,,7.00E-07,P87379,Growth factor receptor-bound protein 2-A (Adapter protein GRB2-A) (SH2/SH3 adapter GRB2-A),Growth factor receptor-bound protein 2-A (Adapter protein GRB2-A) (SH2/SH3 adapter GRB2-A),GO:0005794; GO:0005768; GO:0005154; GO:0007143; GO:0008286; GO:0043560; GO:0007275; GO:0005634,Golgi apparatus; endosome; epidermal growth factor receptor binding; female meiosis; insulin receptor signaling pathway; insulin receptor substrate binding; multicellular organismal development; nucleus,PF00017;PF00018;,,,,,,,,,GRB2A_XENLA,Xenopus laevis (African clawed frog),female meiotic division [GO:0007143]; insulin receptor signaling pathway [GO:0008286]; multicellular organism development [GO:0007275] comp142077_c1_seq19,3906,42.4475,0.34678812,0,0,,1.00E-14,O42287,Intersectin-1,Intersectin-1,GO:0005509; GO:0030054; GO:0006897; GO:0012505; GO:0016020; GO:0043005; GO:0045202,calcium ion binding; cell junction; endocytosis; endomembrane system; membrane; neuron projection; synapse,PF12763;PF00018;PF07653;PF14604;,,,,,,,,,ITSN1_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897] comp142077_c1_seq7,2336,43.1507,0.50757812,0,0,,4.00E-07,Q557J6,Drebrin-like protein (Actin-binding protein 1) (Dabp1) (Actin-binding protein E),Drebrin-like protein (Actin-binding protein 1) (Dabp1) (Actin-binding protein E),GO:0003779; GO:0031252; GO:0006928; GO:0030864; GO:0050765; GO:0097203; GO:0045335; GO:0090382; GO:0031143; GO:0031269,actin binding; cell leading edge; cellular component movement; cortical actin cytoskeleton; negative regulation of phagocytosis; phagocytic cup lip; phagocytic vesicle; phagosome maturation; pseudopodium; pseudopodium assembly,PF00241;PF00018;,,,,,,,,,DBNL_DICDI,Dictyostelium discoideum (Slime mold),aggregation involved in sorocarp development [GO:0031152]; cell motility [GO:0048870]; establishment or maintenance of cell polarity [GO:0007163]; negative regulation of phagocytosis [GO:0050765]; phagosome maturation [GO:0090382]; pseudopodium assembly [GO:0031269] comp142078_c2_seq1,1769,41.5489,0.63165428,164,751,,3.00E-51,Q54S59,WD repeat-containing protein 61 homolog,WD repeat-containing protein 61 homolog,,,PF12894;PF00400;,,,,,,,,,WDR61_DICDI,Dictyostelium discoideum (Slime mold), comp142078_c2_seq2,1756,41.5718,0.66251907,118,360,,2.00E-163,Q6P5M2,WD repeat-containing protein 61,WD repeat-containing protein 61,GO:0016593; GO:0055087; GO:0032968; GO:0045944; GO:0035327,Cdc73/Paf1 complex; Ski complex; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcriptionally active chromatin,PF00400;,6.00E-136,CHOYP_WDR61.1.2,,,,,,,WDR61_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp142080_c1_seq1,2508,33.6523,0.53908489,74,52,,1.00E-23,Q55EF0,Ras-related protein RabT2,Ras-related protein RabT2,GO:0005525; GO:0005886; GO:0007264,GTP binding; plasma membrane; small GTPase mediated signal transduction,PF00071;,9.00E-155,CHOYP_BRAFLDRAFT_131227.1.1,,,,,,,RABT2_DICDI,Dictyostelium discoideum (Slime mold),protein secretion [GO:0009306]; small GTPase mediated signal transduction [GO:0007264]; vesicle docking involved in exocytosis [GO:0006904] comp142080_c1_seq2,1600,36.5,0.56746912,2,0,,2.00E-106,P22127,Ras-related protein Rab-10 (ORA1),Ras-related protein Rab-10 (ORA1),GO:0019003; GO:0005525; GO:0005794; GO:0043001; GO:0007409; GO:0061467; GO:0032869; GO:0005789; GO:0071782; GO:0071786; GO:0016197; GO:0045200; GO:0097051; GO:0032593; GO:0030670; GO:0030859; GO:0072372; GO:0055037; GO:0055038; GO:0007264; GO:0005802,GDP binding; GTP binding; Golgi apparatus; Golgi to plasma membrane protein transport; axonogenesis; basolateral protein localization; cellular response to insulin stimulus; endoplasmic reticulum membrane; endoplasmic reticulum tubular network; endoplasmic reticulum tubular network organization; endosomal transport; establishment of neuroblast polarity; establishment of protein localization to endoplasmic reticulum membrane; insulin-responsive compartment; phagocytic vesicle membrane; polarized epithelial cell differentiation; primary cilium; recycling endosome; recycling endosome membrane; small GTPase mediated signal transduction; trans-Golgi network,PF00071;,6.00E-155,CHOYP_BRAFLDRAFT_131227.1.1,2.00E-94,ruditapes_c10335,,,,,RAB10_DISOM,Diplobatis ommata (Ocellated electric ray) (Discopyge ommata),axonogenesis [GO:0007409]; basolateral protein localization [GO:0061467]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to plasma membrane [GO:0072659]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp142083_c1_seq1,1562,40.525,0.51889221,38,169,,1.00E-147,Q6DEJ5,Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1),Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1),GO:0005524; GO:0005737; GO:0016876; GO:0046872; GO:0043039; GO:0006412,"ATP binding; cytoplasm; ligase activity, forming aminoacyl-tRNA and related compounds; metal ion binding; tRNA aminoacylation; translation",PF07973;,,,,,,,,,AASD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of translational fidelity [GO:0006450]; translation [GO:0006412]; tRNA aminoacylation [GO:0043039] comp142083_c1_seq2,1189,41.127,0.5534125,0,10,,1.00E-19,P61710,Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),GO:0005524; GO:0004813; GO:0006419; GO:0005737; GO:0046872; GO:0000049,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytoplasm; metal ion binding; tRNA binding,PF01411;PF07973;,,,,,,,,,SYA_METMP,Methanococcus maripaludis (strain S2 / LL),alanyl-tRNA aminoacylation [GO:0006419] comp142083_c1_seq4,1560,40.5769,0.51889577,8,49,,1.00E-147,Q7ZYJ9,Alanyl-tRNA editing protein Aarsd1-B (Alanyl-tRNA synthetase domain-containing protein 1-B),Alanyl-tRNA editing protein Aarsd1-B (Alanyl-tRNA synthetase domain-containing protein 1-B),GO:0005524; GO:0004813; GO:0006419; GO:0005737; GO:0046872; GO:0003676,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytoplasm; metal ion binding; nucleic acid binding,PF07973;,8.00E-39,CHOYP_BRAFLDRAFT_127497.1.1,1.00E-85,ruditapes_c19761,,,,,AASDB_XENLA,Xenopus laevis (African clawed frog),alanyl-tRNA aminoacylation [GO:0006419] comp142083_c1_seq5,767,42.1121,0.529098,0,0,,9.00E-07,Q6L1Z4,Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),GO:0005524; GO:0004813; GO:0006419; GO:0005737; GO:0046872; GO:0000049,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytoplasm; metal ion binding; tRNA binding,PF01411;PF07973;,,,,,,,,,SYA_PICTO,Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828),alanyl-tRNA aminoacylation [GO:0006419] comp142083_c1_seq6,424,37.0283,0.28862639,4,27,,,,,,,,,,,7.00E-12,ruditapes2_c2464,,,,,,, comp142085_c0_seq1,1867,36.1007,0.53054538,137,570,,4.00E-26,Q8AXF4,F-box only protein 43 (Early mitotic inhibitor 2) (Emi1-related protein 1) (F-box protein 26) (Xerp1),F-box only protein 43 (Early mitotic inhibitor 2) (Emi1-related protein 1) (F-box protein 26) (Xerp1),GO:0007126; GO:0016567; GO:0008270,meiosis; protein ubiquitination; zinc ion binding,PF00646;PF01485;,,,,,,,,,FBX43_XENLA,Xenopus laevis (African clawed frog),meiotic cell cycle [GO:0051321]; protein ubiquitination [GO:0016567] comp142086_c0_seq12,496,42.9435,0.17699502,12,0,,3.00E-07,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp142086_c0_seq2,500,41.8,0.18711559,7,0,,5.00E-08,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp142090_c0_seq1,2063,37.4697,0.98258059,11,142,,,,,,,,,4.00E-12,CHOYP_SMP_051990.7.7,,,,,,,,, comp142090_c0_seq2,2076,37.2351,0.97484299,22,307,,2.00E-09,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,4.00E-12,CHOYP_SMP_051990.7.7,1.00E-28,ruditapes_c31754,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp142093_c0_seq1,2064,36.3857,0.55952496,443,2205,,3.00E-50,A8QB25,Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) (Octapeptidyl aminopeptidase),Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) (Octapeptidyl aminopeptidase),GO:0046872; GO:0004222; GO:0005759; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; proteolysis,PF01432;,1.00E-32,CHOYP_BRAFLDRAFT_277269.1.1,,,,,,,PMIP_MALGO,Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus), comp142093_c0_seq2,1569,40.6628,0.51900848,115,552,,1.00E-122,A6H611,Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59),Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59),GO:0046872; GO:0004222; GO:0005759; GO:0005739; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; mitochondrion; proteolysis,PF01432;,,,,,,,,,MIPEP_MOUSE,Mus musculus (Mouse),peptide metabolic process [GO:0006518]; protein processing involved in protein targeting to mitochondrion [GO:0006627] comp142094_c0_seq1,2467,36.1167,0.42597526,0,0,,6.00E-51,Q3SX05,"Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial","Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial",GO:0045087; GO:0005739; GO:0005634; GO:0016651; GO:0051341,"innate immune response; mitochondrion; nucleus; oxidoreductase activity, acting on NAD(P)H; regulation of oxidoreductase activity",PF14784;PF06239;,,,,,,,,,ECSIT_BOVIN,Bos taurus (Bovine),innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341] comp142094_c0_seq2,2233,36.9458,0.4100394,0,0,,3.00E-70,Q9U6M0,"Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial","Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial",GO:0045087; GO:0005739; GO:0005634; GO:0016651; GO:0051341,"innate immune response; mitochondrion; nucleus; oxidoreductase activity, acting on NAD(P)H; regulation of oxidoreductase activity",PF14784;PF06239;,,,,,,,,,ECSIT_DROME,Drosophila melanogaster (Fruit fly),defense response [GO:0006952]; innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063] comp142094_c0_seq3,2434,36.2777,0.42765646,0,0,,3.00E-51,Q3SX05,"Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial","Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial",GO:0045087; GO:0005739; GO:0005634; GO:0016651; GO:0051341,"innate immune response; mitochondrion; nucleus; oxidoreductase activity, acting on NAD(P)H; regulation of oxidoreductase activity",PF14784;PF06239;,,,,,,,,,ECSIT_BOVIN,Bos taurus (Bovine),innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341] comp142094_c0_seq6,2200,37.1364,0.41165016,0,0,,5.00E-61,A2VD95,"Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial","Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial",GO:0045087; GO:0005739; GO:0005634; GO:0016651; GO:0051341,"innate immune response; mitochondrion; nucleus; oxidoreductase activity, acting on NAD(P)H; regulation of oxidoreductase activity",PF14784;PF06239;,,,,,,,,,ECSIT_XENLA,Xenopus laevis (African clawed frog),innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341] comp142094_c0_seq7,2213,36.9634,0.40015672,0,0,,3.00E-70,Q9U6M0,"Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial","Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial",GO:0045087; GO:0005739; GO:0005634; GO:0016651; GO:0051341,"innate immune response; mitochondrion; nucleus; oxidoreductase activity, acting on NAD(P)H; regulation of oxidoreductase activity",PF14784;PF06239;,,,,,,,,,ECSIT_DROME,Drosophila melanogaster (Fruit fly),defense response [GO:0006952]; innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063] comp142097_c0_seq1,3270,41.2232,0.51381541,212,711,,5.00E-98,Q69YQ0,Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein),Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein),GO:0030036; GO:0007049; GO:0051301; GO:0016477; GO:0005737; GO:0031941; GO:0005921; GO:0005815; GO:0030835; GO:0007026; GO:0005819,actin cytoskeleton organization; cell cycle; cell division; cell migration; cytoplasm; filamentous actin; gap junction; microtubule organizing center; negative regulation of actin filament depolymerization; negative regulation of microtubule depolymerization; spindle,PF00307;,1.00E-58,CHOYP_CYTSA.1.1,,,,,,,CYTSA_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301] comp142097_c1_seq1,393,41.2214,0.42268473,14,53,,,,,,,,,,,6.00E-12,ruditapes_c18198,,,,,,, comp142099_c1_seq5,1636,41.687,0.51251922,0,0,,1.00E-36,Q4R7V3,FGFR1 oncogene partner,FGFR1 oncogene partner,GO:0005737; GO:0034453; GO:0005815,cytoplasm; microtubule anchoring; microtubule organizing center,PF09398;,1.00E-23,CHOYP_LOC100377771.1.1,,,,,,,FR1OP_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),microtubule anchoring [GO:0034453] comp142099_c1_seq6,1536,41.9271,0.55582294,0,0,,,,,,,,,4.00E-17,CHOYP_LOC100377771.1.1,,,,,,,,, comp142103_c0_seq1,991,45.106,0.50111185,69,282,,7.00E-92,O75529,TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta),TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta),GO:0030914; GO:0043966; GO:0003700; GO:0003713; GO:0033276; GO:0006366,STAGA complex; histone H3 acetylation; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription factor TFTC complex; transcription from RNA polymerase II promoter,PF04494;PF00400;,5.00E-14,CHOYP_BRAFLDRAFT_274913.1.1,,,,,,,TAF5L_HUMAN,Homo sapiens (Human),histone H3 acetylation [GO:0043966]; transcription from RNA polymerase II promoter [GO:0006366] comp142105_c0_seq1,2416,35.8444,0.31019497,2954,23456,,5.00E-120,P55263,Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase),Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase),GO:0006167; GO:0044209; GO:0005524; GO:0004001; GO:0046085; GO:0032922; GO:0005829; GO:0006175; GO:0046872; GO:0005634; GO:0016773; GO:0042102; GO:0010613; GO:0006144; GO:0006166; GO:0043101; GO:0044342,"AMP biosynthetic process; AMP salvage; ATP binding; adenosine kinase activity; adenosine metabolic process; circadian regulation of gene expression; cytosol; dATP biosynthetic process; metal ion binding; nucleus; phosphotransferase activity, alcohol group as acceptor; positive regulation of T cell proliferation; positive regulation of cardiac muscle hypertrophy; purine nucleobase metabolic process; purine ribonucleoside salvage; purine-containing compound salvage; type B pancreatic cell proliferation",PF00294;,8.00E-79,CHOYP_LOC100371695.1.1,,,,,,,ADK_HUMAN,Homo sapiens (Human),adenosine metabolic process [GO:0046085]; AMP salvage [GO:0044209]; circadian regulation of gene expression [GO:0032922]; dATP biosynthetic process [GO:0006175]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; type B pancreatic cell proliferation [GO:0044342] comp142107_c0_seq1,2603,41.6443,0.54594017,26,514,,3.00E-37,Q8TG24,Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT),Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT),GO:0005524; GO:0004020; GO:0019344; GO:0005737; GO:0070814; GO:0009086; GO:0004781; GO:0000103,ATP binding; adenylylsulfate kinase activity; cysteine biosynthetic process; cytoplasm; hydrogen sulfide biosynthetic process; methionine biosynthetic process; sulfate adenylyltransferase (ATP) activity; sulfate assimilation,PF01747;PF14306;,,,,,,,,,MET3_CRYNV,Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii),cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103] comp142107_c0_seq2,2577,42.0256,0.51477289,25,301,,1.00E-38,Q4P460,Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT),Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT),GO:0005524; GO:0004020; GO:0019344; GO:0005737; GO:0070814; GO:0009086; GO:0004781; GO:0000103,ATP binding; adenylylsulfate kinase activity; cysteine biosynthetic process; cytoplasm; hydrogen sulfide biosynthetic process; methionine biosynthetic process; sulfate adenylyltransferase (ATP) activity; sulfate assimilation,PF01747;PF14306;,,,,,,,,,MET3_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103] comp142107_c0_seq3,2588,42.0788,0.52867672,0,87,,0,Q27128,Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPS synthase) (PAPSS) (Sulfurylase kinase) (SK) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)],Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPS synthase) (PAPSS) (Sulfurylase kinase) (SK) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)],GO:0005524; GO:0004020; GO:0004781; GO:0000103,ATP binding; adenylylsulfate kinase activity; sulfate adenylyltransferase (ATP) activity; sulfate assimilation,PF01747;PF14306;,0,CHOYP_PAPSS.1.1,,,,,,,PAPSS_URECA,Urechis caupo (Innkeeper worm) (Spoonworm),sulfate assimilation [GO:0000103] comp142108_c1_seq1,2693,39.6955,0.68972813,0,0,,8.00E-65,Q2T9W3,Coiled-coil domain-containing protein 63,Coiled-coil domain-containing protein 63,,,,,,,,,,,,CCD63_BOVIN,Bos taurus (Bovine),spermatid development [GO:0007286] comp142108_c1_seq2,2689,39.643,0.69293434,0,0,,1.00E-53,B1H228,Coiled-coil domain-containing protein 114,Coiled-coil domain-containing protein 114,GO:0005929; GO:0036157; GO:0036158,cilium; outer dynein arm; outer dynein arm assembly,,,,1.00E-62,ruditapes_c13512,,,,,CC114_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158] comp142108_c1_seq3,2704,39.608,0.69033884,0,0,,8.00E-66,Q2T9W3,Coiled-coil domain-containing protein 63,Coiled-coil domain-containing protein 63,,,,,,,,,,,,CCD63_BOVIN,Bos taurus (Bovine),spermatid development [GO:0007286] comp142108_c1_seq4,2543,40.1101,0.71779884,0,0,,,,,,,,,0,CHOYP_LOC591570.1.1,,,,,,,,, comp142108_c1_seq5,2708,39.6603,0.68715824,0,0,,2.00E-61,Q8NA47,Coiled-coil domain-containing protein 63,Coiled-coil domain-containing protein 63,,,,,,,,,,,,CCD63_HUMAN,Homo sapiens (Human),spermatid development [GO:0007286] comp142108_c1_seq6,2539,40.0945,0.72065387,0,0,,5.00E-66,Q2T9W3,Coiled-coil domain-containing protein 63,Coiled-coil domain-containing protein 63,,,,,,,,,,,,CCD63_BOVIN,Bos taurus (Bovine),spermatid development [GO:0007286] comp142108_c1_seq7,2524,40.1347,0.72346662,0,0,,8.00E-54,B1H228,Coiled-coil domain-containing protein 114,Coiled-coil domain-containing protein 114,GO:0005929; GO:0036157; GO:0036158,cilium; outer dynein arm; outer dynein arm assembly,,0,CHOYP_LOC591570.1.1,,,,,,,CC114_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158] comp142109_c0_seq1,2493,39.6711,0.38218271,754,414,,0,O61492,Flotillin-2,Flotillin-2,GO:0007155; GO:0016600; GO:0035011; GO:0005198,cell adhesion; flotillin complex; melanotic encapsulation of foreign target; structural molecule activity,PF01145;PF15975;,0,CHOYP_LOC100371885.1.1,8.00E-33,ruditapes_c20270,,,,,FLOT2_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; melanotic encapsulation of foreign target [GO:0035011] comp142110_c0_seq1,1994,34.2528,0.99265677,162,195,,1.00E-13,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp142112_c1_seq1,2103,39.2772,0.38719414,6,85,,8.00E-20,Q15573,TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A),TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A),GO:0003677; GO:0000120; GO:0005654; GO:0006355; GO:0006363; GO:0006362; GO:0006366; GO:0006361,"DNA binding; RNA polymerase I transcription factor complex; nucleoplasm; regulation of transcription, DNA-dependent; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter",,,,,,,,,,TAF1A_HUMAN,Homo sapiens (Human),"positive regulation of gene expression, epigenetic [GO:0045815]; regulation of transcription, DNA-templated [GO:0006355]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp142112_c1_seq2,2117,39.2064,0.39864492,35,168,,9.00E-23,Q3B7U2,TATA box-binding protein-associated factor RNA polymerase I subunit A (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription initiation factor SL1/TIF-IB subunit A),TATA box-binding protein-associated factor RNA polymerase I subunit A (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription initiation factor SL1/TIF-IB subunit A),GO:0003677; GO:0000120; GO:0006355; GO:0006360,"DNA binding; RNA polymerase I transcription factor complex; regulation of transcription, DNA-dependent; transcription from RNA polymerase I promoter",,,,,,,,,,TAF1A_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase I promoter [GO:0006360]" comp142114_c0_seq1,1232,41.2338,0.85718405,114,1624,,1.00E-53,Q9U8W8,Techylectin-5A,Techylectin-5A,GO:0030246; GO:0016337; GO:0005576; GO:0046872,carbohydrate binding; cell-cell adhesion; extracellular region; metal ion binding,PF00147;,,,,,,,,,TL5A_TACTR,Tachypleus tridentatus (Japanese horseshoe crab),single organismal cell-cell adhesion [GO:0016337] comp142114_c0_seq2,342,45.3216,0.9826508,12,320,,4.00E-34,Q00546,Tenascin-R (TN-R) (Restrictin),Tenascin-R (TN-R) (Restrictin),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF00147;PF00041;,,,,,,,,,TENR_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; regulation of neurogenesis [GO:0050767] comp142116_c0_seq1,4969,39.9879,0.69115366,88,0,,2.00E-89,Q7ZU45,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,,,,,,,,,,TTC25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp142116_c0_seq11,4722,39.6654,0.71326294,0,0,,8.00E-32,B0BRC9,Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),GO:0097175; GO:0005524; GO:0006040; GO:0005975; GO:0016301; GO:0009254; GO:0016773,"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process; ATP binding; amino sugar metabolic process; carbohydrate metabolic process; kinase activity; peptidoglycan turnover; phosphotransferase activity, alcohol group as acceptor",PF03702;,4.00E-111,CHOYP_LOC581183.1.1,,,,,,,ANMK_ACTPJ,Actinobacillus pleuropneumoniae serotype 3 (strain JL03),"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]" comp142116_c0_seq12,4613,39.5404,0.68430315,0,0,,4.00E-157,Q7ZU45,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,,2.00E-108,CHOYP_LOC581183.1.1,,,,,,,TTC25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp142116_c0_seq3,4957,39.9435,0.6790837,67,0,,2.00E-34,Q6FG11,Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),GO:0097175; GO:0005524; GO:0006040; GO:0005975; GO:0016301; GO:0009254; GO:0016773,"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process; ATP binding; amino sugar metabolic process; carbohydrate metabolic process; kinase activity; peptidoglycan turnover; phosphotransferase activity, alcohol group as acceptor",PF03702;,,,,,,,,,ANMK_ACIAD,Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1),"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]" comp142116_c0_seq4,4735,39.7254,0.70913487,0,0,,6.00E-157,Q7ZU45,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,,4.00E-111,CHOYP_LOC581183.1.1,,,,,,,TTC25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp142116_c0_seq5,4956,39.891,0.68618497,0,0,,2.00E-31,Q9KU38,Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),GO:0097175; GO:0005524; GO:0006040; GO:0005975; GO:0016301; GO:0009254; GO:0016773,"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process; ATP binding; amino sugar metabolic process; carbohydrate metabolic process; kinase activity; peptidoglycan turnover; phosphotransferase activity, alcohol group as acceptor",PF03702;,,,,,,,,,ANMK_VIBCH,Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961),"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]" comp142116_c0_seq7,4944,39.8261,0.68499653,170,0,,9.00E-32,B0BRC9,Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase),GO:0097175; GO:0005524; GO:0006040; GO:0005975; GO:0016301; GO:0009254; GO:0016773,"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process; ATP binding; amino sugar metabolic process; carbohydrate metabolic process; kinase activity; peptidoglycan turnover; phosphotransferase activity, alcohol group as acceptor",PF03702;,,,,,,,,,ANMK_ACTPJ,Actinobacillus pleuropneumoniae serotype 3 (strain JL03),"1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]" comp142116_c0_seq8,4747,39.7304,0.70719821,0,0,,6.00E-157,Q7ZU45,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,,4.00E-111,CHOYP_LOC581183.1.1,,,,,,,TTC25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp142117_c0_seq11,1129,35.4296,0.22828301,9,39,,,,,,,,,2.00E-18,CHOYP_LOC100371136.4.5,,,,,,,,, comp142117_c0_seq12,879,36.9738,0.26794584,15,17,,1.00E-06,O67074,DNA polymerase III subunit epsilon (EC 2.7.7.7),DNA polymerase III subunit epsilon (EC 2.7.7.7),GO:0003677; GO:0006260; GO:0003887; GO:0004527; GO:0046872; GO:0090305,DNA binding; DNA replication; DNA-directed DNA polymerase activity; exonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF00929;,,,,,,,,,DPO3E_AQUAE,Aquifex aeolicus (strain VF5),DNA replication [GO:0006260] comp142121_c2_seq1,2886,38.7387,0.53275863,1163,4101,,2.00E-85,O00541,Pescadillo homolog,Pescadillo homolog,GO:0070545; GO:0008283; GO:0000793; GO:0000466; GO:0000463; GO:0007000; GO:0005654; GO:0030687; GO:0033365; GO:0051726,"PeBoW complex; cell proliferation; condensed chromosome; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleolus organization; nucleoplasm; preribosome, large subunit precursor; protein localization to organelle; regulation of cell cycle",PF16589;PF06732;,9.00E-111,CHOYP_PESC.1.1,,,,,,,PESC_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; nucleolus organization [GO:0007000]; protein localization to organelle [GO:0033365]; regulation of cell cycle [GO:0051726]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]" comp142122_c0_seq1,3067,39.387,0.67351605,11,26,,,,,,,,,8.00E-106,CHOYP_KCMF1.1.1,,,,,,,,, comp142122_c0_seq2,3085,39.4814,0.67450465,19,50,,8.00E-99,Q6GPB6,E3 ubiquitin-protein ligase KCMF1 (EC 6.3.2.-),E3 ubiquitin-protein ligase KCMF1 (EC 6.3.2.-),GO:0016874; GO:0008270,ligase activity; zinc ion binding,PF05605;PF00569;,,,,,,,,,KCMF1_XENLA,Xenopus laevis (African clawed frog), comp142123_c0_seq1,4746,43.6157,0.61871102,0,0,,3.00E-151,Q2V2M9,FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),GO:0030018; GO:0007015; GO:0005737; GO:0005856; GO:0030837; GO:0005730; GO:0045214,Z disc; actin filament organization; cytoplasm; cytoskeleton; negative regulation of actin filament polymerization; nucleolus; sarcomere organization,PF02181;,0,CHOYP_FHOD3.2.2,,,,,,,FHOD3_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] comp142123_c0_seq10,4791,43.6235,0.61727523,0,0,,4.00E-151,Q2V2M9,FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),GO:0030018; GO:0007015; GO:0005737; GO:0005856; GO:0030837; GO:0005730; GO:0045214,Z disc; actin filament organization; cytoplasm; cytoskeleton; negative regulation of actin filament polymerization; nucleolus; sarcomere organization,PF02181;,0,CHOYP_FHOD3.2.2,,,,,,,FHOD3_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] comp142123_c0_seq12,4759,43.6436,0.62084838,0,0,,5.00E-120,Q6P9Q4,FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1),FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1),GO:0007015; GO:0032059; GO:0005829; GO:0005634; GO:0051496; GO:0045944; GO:0001725,actin filament organization; bleb; cytosol; nucleus; positive regulation of stress fiber assembly; positive regulation of transcription from RNA polymerase II promoter; stress fiber,PF02181;,3.00E-176,CHOYP_LOC100869084.1.1,,,,,,,FHOD1_MOUSE,Mus musculus (Mouse),positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp142123_c0_seq14,4777,43.6466,0.62273582,0,0,,2.00E-145,Q2V2M9,FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),GO:0030018; GO:0007015; GO:0005737; GO:0005856; GO:0030837; GO:0005730; GO:0045214,Z disc; actin filament organization; cytoplasm; cytoskeleton; negative regulation of actin filament polymerization; nucleolus; sarcomere organization,PF02181;,0,CHOYP_FHOD3.2.2,,,,,,,FHOD3_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] comp142123_c0_seq3,2145,41.3986,0.51603705,0,0,,4.00E-15,Q54PI9,Formin-I,Formin-I,GO:0005522,profilin binding,PF02181;,,,,,,,,,FORI_DICDI,Dictyostelium discoideum (Slime mold), comp142123_c0_seq6,4728,43.6125,0.61679055,0,0,,3.00E-151,Q2V2M9,FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),GO:0030018; GO:0007015; GO:0005737; GO:0005856; GO:0030837; GO:0005730; GO:0045214,Z disc; actin filament organization; cytoplasm; cytoskeleton; negative regulation of actin filament polymerization; nucleolus; sarcomere organization,PF02181;,0,CHOYP_FHOD3.2.2,,,,,,,FHOD3_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] comp142123_c0_seq8,2113,41.4103,0.51222581,0,0,,4.00E-15,Q54PI9,Formin-I,Formin-I,GO:0005522,profilin binding,PF02181;,,,,,,,,,FORI_DICDI,Dictyostelium discoideum (Slime mold), comp142123_c0_seq9,4804,43.6095,0.61619157,0,0,,,,,,,,,0,CHOYP_FHOD3.2.2,,,,,,,,, comp142126_c1_seq1,2042,39.569,0.50155495,35,25,,,,,,,,,3.00E-27,CHOYP_LOC100891656.1.1,,,,,,,,, comp142126_c1_seq2,2044,39.726,0.49739015,48,19,,,,,,,,,3.00E-27,CHOYP_LOC100891656.1.1,,,,,,,,, comp142127_c0_seq1,4765,38.2581,0.38736124,836,1777,,0,Q80U96,Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog),Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog),GO:0015030; GO:0003723; GO:0005642; GO:0005737; GO:0000776; GO:0051028; GO:0000122; GO:0005730; GO:0006611; GO:0042493; GO:0030529,Cajal body; RNA binding; annulate lamellae; cytoplasm; kinetochore; mRNA transport; negative regulation of transcription from RNA polymerase II promoter; nucleolus; protein export from nucleus; response to drug; ribonucleoprotein complex,PF08767;PF03810;PF08389;,0,CHOYP_XPO1.1.1,,,,,,,XPO1_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein export from nucleus [GO:0006611]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to drug [GO:0042493]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] comp142128_c0_seq2,1378,42.2351,0.56603758,82,50,,9.00E-134,Q00422,GA-binding protein alpha chain (GABP subunit alpha),GA-binding protein alpha chain (GABP subunit alpha),GO:0000978; GO:0001228; GO:0003682; GO:0001701; GO:0045653; GO:0000122; GO:0000790; GO:0005634; GO:0045944; GO:0046982; GO:0044212,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chromatin binding; in utero embryonic development; negative regulation of megakaryocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; transcription regulatory region DNA binding,PF00178;PF11620;PF02198;,9.00E-158,CHOYP_GABPA.1.1,,,,,,,GABPA_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp142128_c0_seq3,987,42.1479,0.49354222,13,0,,2.00E-111,Q00422,GA-binding protein alpha chain (GABP subunit alpha),GA-binding protein alpha chain (GABP subunit alpha),GO:0000978; GO:0001228; GO:0003682; GO:0001701; GO:0045653; GO:0000122; GO:0000790; GO:0005634; GO:0045944; GO:0046982; GO:0044212,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chromatin binding; in utero embryonic development; negative regulation of megakaryocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; transcription regulatory region DNA binding,PF00178;PF11620;PF02198;,,,1.00E-12,ruditapes_c14010,,,,,GABPA_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp142128_c0_seq5,355,45.9155,0.37838138,0,0,,,,,,,,,2.00E-32,CHOYP_GABPA.1.1,,,,,,,,, comp142129_c0_seq1,3030,41.8482,0.39178076,7,101,,6.00E-27,O60081,Uncharacterized protein C1494.07,Uncharacterized protein C1494.07,GO:0005829; GO:0005634; GO:0043234; GO:0030488,cytosol; nucleus; protein complex; tRNA methylation,PF10350;,,,,,,,,,YQK7_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),tRNA methylation [GO:0030488] comp142129_c0_seq2,2922,42.3682,0.38858834,0,24,,6.00E-80,A8C756,Thyroid adenoma-associated protein homolog,Thyroid adenoma-associated protein homolog,,,PF10350;,6.00E-37,CHOYP_THADA.1.2,,,,,,,THADA_MOUSE,Mus musculus (Mouse), comp142133_c1_seq1,1312,45.5793,0.72129688,316,671,,2.00E-48,Q8CFD1,RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RNA-binding motif protein 45),RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RNA-binding motif protein 45),GO:0003723; GO:0030154; GO:0005737; GO:0007399; GO:0000166; GO:0005634,RNA binding; cell differentiation; cytoplasm; nervous system development; nucleotide binding; nucleus,PF00076;,7.00E-45,CHOYP_DPSE_GA12086.1.2,,,,,,,RBM45_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp142133_c5_seq4,2436,33.6207,0.53794351,455,1521,,,,,,,,,4.00E-13,CHOYP_contig_037248,,,,,,,,, comp142133_c5_seq5,910,42.1978,0.27231011,29,102,,1.00E-06,Q93W34,Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C),Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C),GO:0005829; GO:0006397; GO:0000166; GO:0005634; GO:0008143,cytosol; mRNA processing; nucleotide binding; nucleus; poly(A) RNA binding,PF00076;,,,,,,,,,RP45C_ARATH,Arabidopsis thaliana (Mouse-ear cress),mRNA processing [GO:0006397] comp142141_c0_seq1,2167,41.0706,0.51458479,746,481,,5.00E-22,A1L2F3,Nucleolar and spindle-associated protein 1 (NuSAP),Nucleolar and spindle-associated protein 1 (NuSAP),GO:0003677; GO:0005737; GO:0040001; GO:0005874; GO:0007067; GO:0000281; GO:0001755; GO:0005634; GO:0005819,DNA binding; cytoplasm; establishment of mitotic spindle localization; microtubule; mitosis; mitotic cytokinesis; neural crest cell migration; nucleus; spindle,PF16006;,,,,,,,,,NUSAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),establishment of mitotic spindle localization [GO:0040001]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; neural crest cell migration [GO:0001755] comp142142_c1_seq2,1746,43.1271,0.60240534,157,861,,0,Q00612,Glucose-6-phosphate 1-dehydrogenase X (G6PD) (EC 1.1.1.49),Glucose-6-phosphate 1-dehydrogenase X (G6PD) (EC 1.1.1.49),GO:0050661; GO:0006741; GO:0001998; GO:0048821; GO:0051156; GO:0004345; GO:0006749; GO:0032613; GO:0032615; GO:0019322; GO:0006098; GO:0040014; GO:0006979; GO:0002033,NADP binding; NADP biosynthetic process; angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure; erythrocyte development; glucose 6-phosphate metabolic process; glucose-6-phosphate dehydrogenase activity; glutathione metabolic process; interleukin-10 production; interleukin-12 production; pentose biosynthetic process; pentose-phosphate shunt; regulation of multicellular organism growth; response to oxidative stress; vasodilation by angiotensin involved in regulation of systemic arterial blood pressure,PF02781;PF00479;,0,CHOYP_G6PD.1.2,,,,,,,G6PD1_MOUSE,Mus musculus (Mouse),"angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; cytokine production [GO:0001816]; erythrocyte development [GO:0048821]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; interleukin-10 production [GO:0032613]; interleukin-12 production [GO:0032615]; NADP biosynthetic process [GO:0006741]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of protein glutathionylation [GO:0010734]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979]; ribose phosphate biosynthetic process [GO:0046390]; vasodilation by angiotensin involved in regulation of systemic arterial blood pressure [GO:0002033]" comp142143_c0_seq1,2848,40.5548,0.47422122,39,213,,0,Q96RQ3,"Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)","Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)",GO:0005524; GO:0009374; GO:0004075; GO:0006768; GO:0005829; GO:0006552; GO:0046872; GO:0004485; GO:0005743; GO:0005759,ATP binding; biotin binding; biotin carboxylase activity; biotin metabolic process; cytosol; leucine catabolic process; metal ion binding; methylcrotonoyl-CoA carboxylase activity; mitochondrial inner membrane; mitochondrial matrix,PF02785;PF00289;PF00364;PF02786;,,,,,,,,,MCCA_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552]; protein heterooligomerization [GO:0051291] comp142143_c0_seq2,2847,40.569,0.48334683,31,156,,0,Q96RQ3,"Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)","Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)",GO:0005524; GO:0009374; GO:0004075; GO:0006768; GO:0005829; GO:0006552; GO:0046872; GO:0004485; GO:0005743; GO:0005759,ATP binding; biotin binding; biotin carboxylase activity; biotin metabolic process; cytosol; leucine catabolic process; metal ion binding; methylcrotonoyl-CoA carboxylase activity; mitochondrial inner membrane; mitochondrial matrix,PF02785;PF00289;PF00364;PF02786;,0,CHOYP_MCCA.1.1,,,,,,,MCCA_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552]; protein heterooligomerization [GO:0051291] comp142144_c0_seq1,3760,38.5904,0.43945335,0,0,,6.00E-31,O48626,Centromere/kinetochore protein zw10 homolog,Centromere/kinetochore protein zw10 homolog (AtZW10) (MAG2-interacting protein 1),GO:0051301; GO:0007059; GO:0000777; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; chromosome segregation; condensed chromosome kinetochore; cytoplasm; mitosis; nucleus; spindle,PF06248;,,,,,,,,,ZW10_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell division [GO:0051301]; chromosome segregation [GO:0007059]; ER to Golgi vesicle-mediated transport [GO:0006888]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; protein transport [GO:0015031] comp142144_c0_seq2,3384,39.8936,0.43422011,0,0,,2.00E-135,O43264,Centromere/kinetochore protein zw10 homolog,Centromere/kinetochore protein zw10 homolog,GO:0006888; GO:0051301; GO:0019237; GO:0000777; GO:0005829; GO:0005783; GO:0005789; GO:0000132; GO:0000776; GO:0005828; GO:0007126; GO:0007093; GO:0007080; GO:0005634; GO:0006461; GO:0034501; GO:0015031; GO:0007096; GO:0000922,ER to Golgi vesicle-mediated transport; cell division; centromeric DNA binding; condensed chromosome kinetochore; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; establishment of mitotic spindle orientation; kinetochore; kinetochore microtubule; meiosis; mitotic cell cycle checkpoint; mitotic metaphase plate congression; nucleus; protein complex assembly; protein localization to kinetochore; protein transport; regulation of exit from mitosis; spindle pole,PF06248;,4.00E-27,CHOYP_ZW10.1.1,,,,,,,ZW10_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein complex assembly [GO:0006461]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; sister chromatid cohesion [GO:0007062]" comp142144_c0_seq3,3760,38.6968,0.43639725,3,1,,6.00E-31,O48626,Centromere/kinetochore protein zw10 homolog,Centromere/kinetochore protein zw10 homolog (AtZW10) (MAG2-interacting protein 1),GO:0051301; GO:0007059; GO:0000777; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; chromosome segregation; condensed chromosome kinetochore; cytoplasm; mitosis; nucleus; spindle,PF06248;,,,,,,,,,ZW10_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell division [GO:0051301]; chromosome segregation [GO:0007059]; ER to Golgi vesicle-mediated transport [GO:0006888]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; protein transport [GO:0015031] comp142144_c0_seq4,3384,40.0118,0.43100197,0,0,,5.00E-141,O43264,Centromere/kinetochore protein zw10 homolog,Centromere/kinetochore protein zw10 homolog,GO:0006888; GO:0051301; GO:0019237; GO:0000777; GO:0005829; GO:0005783; GO:0005789; GO:0000132; GO:0000776; GO:0005828; GO:0007126; GO:0007093; GO:0007080; GO:0005634; GO:0006461; GO:0034501; GO:0015031; GO:0007096; GO:0000922,ER to Golgi vesicle-mediated transport; cell division; centromeric DNA binding; condensed chromosome kinetochore; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; establishment of mitotic spindle orientation; kinetochore; kinetochore microtubule; meiosis; mitotic cell cycle checkpoint; mitotic metaphase plate congression; nucleus; protein complex assembly; protein localization to kinetochore; protein transport; regulation of exit from mitosis; spindle pole,PF06248;,4.00E-27,CHOYP_ZW10.1.1,,,,,,,ZW10_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein complex assembly [GO:0006461]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; sister chromatid cohesion [GO:0007062]" comp142146_c0_seq1,1650,44.303,0.37633932,335,1356,,3.00E-140,P34275,Probable acyl-CoA dehydrogenase 6 (Probable isovaleryl-CoA dehydrogenase) (IVD) (EC 1.3.8.4),Probable acyl-CoA dehydrogenase 6 (Probable isovaleryl-CoA dehydrogenase) (IVD) (EC 1.3.8.4),GO:0003995; GO:0050660; GO:0006552,acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; leucine catabolic process,PF00441;PF02770;PF02771;,0,CHOYP_PDE8B.1.1,,,,,,,IVD_CAEEL,Caenorhabditis elegans,fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]; lipid homeostasis [GO:0055088] comp142147_c0_seq1,872,38.8761,0.24570818,48,67,,2.00E-41,Q6AXK4,BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex),BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex),GO:0070531; GO:0070552; GO:0031572; GO:0016568; GO:0005737; GO:0006302; GO:0045739; GO:0070536; GO:0010212,BRCA1-A complex; BRISC complex; G2 DNA damage checkpoint; chromatin modification; cytoplasm; double-strand break repair; positive regulation of DNA repair; protein K63-linked deubiquitination; response to ionizing radiation,,,,,,,,,,BABA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] comp142148_c0_seq3,3504,35.7877,0.5174799,109,71,,1.00E-87,Q06440,Coronin-like protein,Coronin-like protein,GO:0030479; GO:0051666; GO:0051015; GO:0007015; GO:0008017; GO:0007017; GO:0034316; GO:2000601; GO:0030674,"actin cortical patch; actin cortical patch localization; actin filament binding; actin filament organization; microtubule binding; microtubule-based process; negative regulation of Arp2/3 complex-mediated actin nucleation; positive regulation of Arp2/3 complex-mediated actin nucleation; protein binding, bridging",PF08953;PF00400;,,,,,,,,,CORO_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin cortical patch localization [GO:0051666]; actin filament organization [GO:0007015]; microtubule-based process [GO:0007017]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601] comp142148_c0_seq4,3123,36.3753,0.50284053,35,22,,4.00E-145,Q5NVK4,Coronin-1B,Coronin-1B,GO:0015629; GO:0030036; GO:0005737,actin cytoskeleton; actin cytoskeleton organization; cytoplasm,PF08953;PF00400;,,,,,,,,,COR1B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp142149_c2_seq6,2064,40.4554,0.57579714,31,1025,,3.00E-133,Q64261,Cyclin-dependent kinase 6 (EC 2.7.11.22) (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE),Cyclin-dependent kinase 6 (EC 2.7.11.22) (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE),GO:0005524; GO:0007219; GO:0033077; GO:0043697; GO:0051301; GO:0000307; GO:0004693; GO:0005737; GO:0042063; GO:0002244; GO:0060218; GO:0016301; GO:0045786; GO:2000773; GO:0050680; GO:0045638; GO:0045668; GO:0005634; GO:0001954; GO:0048146; GO:0010628; GO:0045646; GO:0009615; GO:0001726; GO:0003323,ATP binding; Notch signaling pathway; T cell differentiation in thymus; cell dedifferentiation; cell division; cyclin-dependent protein kinase holoenzyme complex; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; gliogenesis; hematopoietic progenitor cell differentiation; hematopoietic stem cell differentiation; kinase activity; negative regulation of cell cycle; negative regulation of cellular senescence; negative regulation of epithelial cell proliferation; negative regulation of myeloid cell differentiation; negative regulation of osteoblast differentiation; nucleus; positive regulation of cell-matrix adhesion; positive regulation of fibroblast proliferation; positive regulation of gene expression; regulation of erythrocyte differentiation; response to virus; ruffle; type B pancreatic cell development,PF00069;,1.00E-94,CHOYP_LOC100371039.1.1,,,,,,,CDK6_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; gliogenesis [GO:0042063]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; hemopoiesis [GO:0030097]; negative regulation of cell cycle [GO:0045786]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323] comp14214_c0_seq1,268,39.5522,0.60045479,3,0,,1.00E-29,Q99LJ2,Ankyrin repeat and BTB/POZ domain-containing protein 1,Ankyrin repeat and BTB/POZ domain-containing protein 1,GO:0005737; GO:0005730; GO:0005886; GO:0003746,cytoplasm; nucleolus; plasma membrane; translation elongation factor activity,PF12796;PF00651;,1.00E-15,CHOYP_BRAFLDRAFT_276832.1.2,,,,,,,ABTB1_MOUSE,Mus musculus (Mouse), comp142150_c0_seq1,2568,32.5545,0.69144573,3270,20211,,4.00E-44,Q9VZS3,Protein translation factor SUI1 homolog,Protein translation factor SUI1 homolog,GO:0071456; GO:0006417; GO:0003743,cellular response to hypoxia; regulation of translation; translation initiation factor activity,PF01253;,4.00E-45,CHOYP_EIF1B.2.3,3.00E-89,ruditapes_c534,,,,,SUI1_DROME,Drosophila melanogaster (Fruit fly),cellular response to hypoxia [GO:0071456]; regulation of translation [GO:0006417]; translation [GO:0006412] comp142151_c1_seq1,3421,41.4499,0.4474519,0,0,,2.00E-117,P48768,Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0033280; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; plasma membrane; response to vitamin D; telencephalon development,PF03160;PF01699;PF16494;,1.00E-103,CHOYP_BRAFLDRAFT_78683.4.4,,,,,,,NAC2_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp142151_c1_seq10,239,39.749,0.42781498,0,5,,3.00E-10,P70549,Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0071320; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0042383; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; cellular response to cAMP; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; sarcolemma; telencephalon development,PF03160;PF01699;PF16494;,,,,,,,,,NAC3_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp142151_c1_seq2,3442,41.3132,0.43341154,72,0,,4.00E-07,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,4.00E-97,CHOYP_BRAFLDRAFT_78683.3.4,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp142151_c1_seq3,3478,41.4894,0.45954832,47,0,,4.00E-77,P70549,Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0071320; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0042383; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; cellular response to cAMP; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; sarcolemma; telencephalon development,PF03160;PF01699;PF16494;,,,,,,,,,NAC3_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp142151_c1_seq4,1423,42.5861,0.44016625,0,0,,7.00E-08,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp142151_c1_seq6,3499,41.3261,0.45297674,0,0,,2.00E-114,P57103,Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3),GO:0007596; GO:0060402; GO:0005432; GO:0007154; GO:0071320; GO:0043197; GO:0016021; GO:0006811; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0042383; GO:0021537; GO:0055085,blood coagulation; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; cellular response to cAMP; dendritic spine; integral to membrane; ion transport; microtubule; mitochondrion; neuronal cell body; plasma membrane; sarcolemma; telencephalon development; transmembrane transport,PF03160;PF01699;PF16494;,,,,,,,,,NAC3_HUMAN,Homo sapiens (Human),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537] comp142151_c1_seq8,1402,42.9387,0.44024588,0,0,,4.00E-13,Q8CGQ8,Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4),Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4),GO:0008273; GO:0005432; GO:0005887; GO:0015293,"calcium, potassium:sodium antiporter activity; calcium:sodium antiporter activity; integral to plasma membrane; symporter activity",PF01699;,6.00E-97,CHOYP_BRAFLDRAFT_78683.4.4,,,,,,,NCKX4_MOUSE,Mus musculus (Mouse),amelogenesis [GO:0097186]; cellular calcium ion homeostasis [GO:0006874]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] comp142152_c0_seq1,2177,29.6279,0.64936153,100,290,,2.00E-33,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,4.00E-44,CHOYP_LOC100892567.5.8,9.00E-25,ruditapes_c9179,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp142154_c0_seq1,1980,35.404,0.43395411,179,1872,,4.00E-95,O95801,Tetratricopeptide repeat protein 4 (TPR repeat protein 4),Tetratricopeptide repeat protein 4 (TPR repeat protein 4),,,,1.00E-24,CHOYP_TTC4.1.1,,,,,,,TTC4_HUMAN,Homo sapiens (Human), comp142155_c0_seq1,1595,36.8652,0.57263911,6,41,,6.00E-16,Q7ZVC9,Small acidic protein,Small acidic protein,,,PF15477;,,,,,,,,,SMAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142155_c0_seq2,1606,36.4259,0.56362255,0,0,,6.00E-16,Q7ZVC9,Small acidic protein,Small acidic protein,,,PF15477;,,,,,,,,,SMAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142155_c0_seq4,1663,36.3199,0.58424423,0,0,,8.00E-14,Q0IIX4,Small acidic protein,Small acidic protein,,,PF15477;,,,,,,,,,SMAP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142157_c4_seq1,1080,41.1111,1.05704132,88,67,,2.00E-11,Q2NNR5,Cysteinyl leukotriene receptor 1 (CysLTR1) (Cysteinyl leukotriene D4 receptor) (LTD4 receptor),Cysteinyl leukotriene receptor 1 (CysLTR1) (Cysteinyl leukotriene D4 receptor) (LTD4 receptor),GO:0006816; GO:0006935; GO:0005887; GO:0004974,calcium ion transport; chemotaxis; integral to plasma membrane; leukotriene receptor activity,PF00001;,,,,,,,,,CLTR1_CAVPO,Cavia porcellus (Guinea pig),calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935] comp142158_c0_seq2,1117,43.1513,0.56642254,15,0,,1.00E-45,Q99700,Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein),Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein),GO:0005794; GO:0003723; GO:0016070; GO:0050658; GO:0008219; GO:0021702; GO:0033962; GO:0010494; GO:0048872; GO:0040015; GO:0002091; GO:0050905; GO:0048812; GO:0005634; GO:0048471; GO:0005844; GO:0006417; GO:0034063; GO:0005802,Golgi apparatus; RNA binding; RNA metabolic process; RNA transport; cell death; cerebellar Purkinje cell differentiation; cytoplasmic mRNA processing body assembly; cytoplasmic stress granule; homeostasis of number of cells; negative regulation of multicellular organism growth; negative regulation of receptor internalization; neuromuscular process; neuron projection morphogenesis; nucleus; perinuclear region of cytoplasm; polysome; regulation of translation; stress granule assembly; trans-Golgi network,PF06741;PF07145;PF14438;,,,,,,,,,ATX2_HUMAN,Homo sapiens (Human),cytoplasmic mRNA processing body assembly [GO:0033962]; negative regulation of receptor internalization [GO:0002091]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; regulation of translation [GO:0006417]; RNA metabolic process [GO:0016070]; RNA transport [GO:0050658]; stress granule assembly [GO:0034063] comp142158_c0_seq6,1152,42.4479,0.66417101,0,6,,9.00E-46,Q99700,Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein),Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein),GO:0005794; GO:0003723; GO:0016070; GO:0050658; GO:0008219; GO:0021702; GO:0033962; GO:0010494; GO:0048872; GO:0040015; GO:0002091; GO:0050905; GO:0048812; GO:0005634; GO:0048471; GO:0005844; GO:0006417; GO:0034063; GO:0005802,Golgi apparatus; RNA binding; RNA metabolic process; RNA transport; cell death; cerebellar Purkinje cell differentiation; cytoplasmic mRNA processing body assembly; cytoplasmic stress granule; homeostasis of number of cells; negative regulation of multicellular organism growth; negative regulation of receptor internalization; neuromuscular process; neuron projection morphogenesis; nucleus; perinuclear region of cytoplasm; polysome; regulation of translation; stress granule assembly; trans-Golgi network,PF06741;PF07145;PF14438;,,,,,,,,,ATX2_HUMAN,Homo sapiens (Human),cytoplasmic mRNA processing body assembly [GO:0033962]; negative regulation of receptor internalization [GO:0002091]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; regulation of translation [GO:0006417]; RNA metabolic process [GO:0016070]; RNA transport [GO:0050658]; stress granule assembly [GO:0034063] comp142159_c0_seq1,2075,38.0723,0.54890897,0,0,,1.00E-77,A7YWI9,Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein),Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein),GO:0070260; GO:0016605; GO:0005737; GO:0006302; GO:0000287; GO:0030145; GO:0004518; GO:0090305; GO:0005730; GO:0003697; GO:0036317,5'-tyrosyl-DNA phosphodiesterase activity; PML body; cytoplasm; double-strand break repair; magnesium ion binding; manganese ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleolus; single-stranded DNA binding; tyrosyl-RNA phosphodiesterase activity,PF03372;,,,,,,,,,TYDP2_BOVIN,Bos taurus (Bovine),double-strand break repair [GO:0006302] comp142159_c0_seq2,2105,37.6722,0.56643369,11,76,,2.00E-76,A5D8M0,Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein homolog),Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein homolog),GO:0070260; GO:0016605; GO:0006302; GO:0000287; GO:0030145; GO:0004518; GO:0090305; GO:0003697,5'-tyrosyl-DNA phosphodiesterase activity; PML body; double-strand break repair; magnesium ion binding; manganese ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; single-stranded DNA binding,PF03372;,,,,,,,,,TYDP2_XENLA,Xenopus laevis (African clawed frog),double-strand break repair [GO:0006302] comp142159_c0_seq3,2053,38.2854,0.57543274,22,56,,9.00E-78,A7YWI9,Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein),Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein),GO:0070260; GO:0016605; GO:0005737; GO:0006302; GO:0000287; GO:0030145; GO:0004518; GO:0090305; GO:0005730; GO:0003697; GO:0036317,5'-tyrosyl-DNA phosphodiesterase activity; PML body; cytoplasm; double-strand break repair; magnesium ion binding; manganese ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleolus; single-stranded DNA binding; tyrosyl-RNA phosphodiesterase activity,PF03372;,2.00E-21,CHOYP_ISCW_ISCW020529.1.1,,,,,,,TYDP2_BOVIN,Bos taurus (Bovine),double-strand break repair [GO:0006302] comp142159_c0_seq4,2083,37.9261,0.53826149,11,60,,,,,,,,,3.00E-21,CHOYP_ISCW_ISCW020529.1.1,,,,,,,,, comp142162_c0_seq1,3190,36.5204,0.64498881,530,8,,0,Q00194,"cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)","cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)",GO:0030553; GO:0005887; GO:0005222; GO:0005223; GO:0001750; GO:0042622; GO:0007603; GO:0042391; GO:0007601; GO:0005249,"cGMP binding; integral to plasma membrane; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; photoreceptor outer segment; photoreceptor outer segment membrane; phototransduction, visible light; regulation of membrane potential; visual perception; voltage-gated potassium channel activity",PF16526;PF00027;PF00520;,2.00E-94,CHOYP_CNGA1.1.1,,,,,,,CNGA1_BOVIN,Bos taurus (Bovine),cation transport [GO:0006812]; regulation of membrane potential [GO:0042391]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp142162_c0_seq2,2925,37.812,0.65732974,516,0,male,0,Q00194,"cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)","cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)",GO:0030553; GO:0005887; GO:0005222; GO:0005223; GO:0001750; GO:0042622; GO:0007603; GO:0042391; GO:0007601; GO:0005249,"cGMP binding; integral to plasma membrane; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; photoreceptor outer segment; photoreceptor outer segment membrane; phototransduction, visible light; regulation of membrane potential; visual perception; voltage-gated potassium channel activity",PF16526;PF00027;PF00520;,3.00E-47,CHOYP_ISCW_ISCW013674.1.1,,,,,,,CNGA1_BOVIN,Bos taurus (Bovine),cation transport [GO:0006812]; regulation of membrane potential [GO:0042391]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp142163_c0_seq1,3079,42.1565,0.40719494,309,3153,,0,A6QLH6,N-terminal kinase-like protein (SCY1-like protein 1),N-terminal kinase-like protein (SCY1-like protein 1),GO:0005524; GO:0005794; GO:0005801; GO:0005793; GO:0005815; GO:0004672; GO:0006890,"ATP binding; Golgi apparatus; cis-Golgi network; endoplasmic reticulum-Golgi intermediate compartment; microtubule organizing center; protein kinase activity; retrograde vesicle-mediated transport, Golgi to ER",PF00069;,2.00E-169,CHOYP_BRAFLDRAFT_101148.1.1,,,,,,,NTKL_BOVIN,Bos taurus (Bovine),"retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp142165_c2_seq1,1189,41.2952,0.37540705,91,833,,1.00E-85,Q5RD94,Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6),Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF04934;,1.00E-53,CHOYP_BRAFLDRAFT_202253.1.1,,,,,,,MED6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"transcription, DNA-templated [GO:0006351]" comp142166_c0_seq2,2368,44.4257,0.40468664,4,0,,0,P21447,Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3),Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3),GO:0005524; GO:0042626; GO:0000139; GO:0016324; GO:0015893; GO:0016021; GO:0046581; GO:0008559,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; Golgi membrane; apical plasma membrane; drug transport; integral to membrane; intercellular canaliculus; xenobiotic-transporting ATPase activity",PF00664;PF00005;,3.00E-84,CHOYP_MDR1.1.2,,,,,,,MDR1A_MOUSE,Mus musculus (Mouse),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; drug transmembrane transport [GO:0006855]; drug transport [GO:0015893]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; stem cell proliferation [GO:0072089]; transmembrane transport [GO:0055085]" comp142166_c0_seq3,3589,43.2711,0.42166853,201,95,,0,P21447,Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3),Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3),GO:0005524; GO:0042626; GO:0000139; GO:0016324; GO:0015893; GO:0016021; GO:0046581; GO:0008559,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; Golgi membrane; apical plasma membrane; drug transport; integral to membrane; intercellular canaliculus; xenobiotic-transporting ATPase activity",PF00664;PF00005;,5.00E-103,CHOYP_MDR3.3.3,,,,,,,MDR1A_MOUSE,Mus musculus (Mouse),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; drug transmembrane transport [GO:0006855]; drug transport [GO:0015893]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; stem cell proliferation [GO:0072089]; transmembrane transport [GO:0055085]" comp142166_c0_seq4,957,44.5141,0.44297554,0,0,,2.00E-10,P75059,Spermidine/putrescine import ATP-binding protein PotA (EC 3.6.3.31),Spermidine/putrescine import ATP-binding protein PotA (EC 3.6.3.31),GO:0005524; GO:0006200; GO:0005886; GO:0015594; GO:0015595,ATP binding; ATP catabolic process; plasma membrane; putrescine-importing ATPase activity; spermidine-importing ATPase activity,PF00005;,7.00E-18,CHOYP_MDR1.1.2,,,,,,,POTA_MYCPN,Mycoplasma pneumoniae (strain ATCC 29342 / M129), comp142166_c1_seq4,1444,45.1524,0.48111705,7,0,,1.00E-60,Q6PCS4,Rho GTPase-activating protein 29 (Rho-type GTPase-activating protein 29),Rho GTPase-activating protein 29 (Rho-type GTPase-activating protein 29),GO:0005096; GO:0005622; GO:0035556; GO:0046872; GO:0043547,GTPase activator activity; intracellular; intracellular signal transduction; metal ion binding; positive regulation of GTPase activity,PF00130;PF00620;,,,,,,,,,RHG29_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),intracellular signal transduction [GO:0035556] comp142166_c2_seq1,1536,44.401,0.4361973,50,46,,7.00E-49,Q6DE55,Minor histocompatibility protein HA-1,Minor histocompatibility protein HA-1,GO:0005096; GO:0005622; GO:0035556; GO:0046872; GO:0043547,GTPase activator activity; intracellular; intracellular signal transduction; metal ion binding; positive regulation of GTPase activity,PF00130;PF00620;,3.00E-44,CHOYP_BRAFLDRAFT_124122.1.1,,,,,,,HMHA1_XENLA,Xenopus laevis (African clawed frog),intracellular signal transduction [GO:0035556] comp142166_c2_seq2,781,43.662,0.56705894,0,0,,7.00E-17,Q3TBD2,Minor histocompatibility protein HA-1,Minor histocompatibility protein HA-1,GO:0005096; GO:0005622; GO:0035556; GO:0046872; GO:0043547,GTPase activator activity; intracellular; intracellular signal transduction; metal ion binding; positive regulation of GTPase activity,PF00620;,,,,,,,,,HMHA1_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556] comp142172_c0_seq1,2058,41.3508,0.52412745,8,20,,1.00E-55,Q9VSL7,Zinc transporter foi (Protein fear-of-intimacy) (Protein kastchen),Zinc transporter foi (Protein fear-of-intimacy) (Protein kastchen),GO:0035147; GO:0009986; GO:0007417; GO:0035262; GO:0007506; GO:0005887; GO:0022008; GO:0007280; GO:0005385,"branch fusion, open tracheal system; cell surface; central nervous system development; gonad morphogenesis; gonadal mesoderm development; integral to plasma membrane; neurogenesis; pole cell migration; zinc ion transmembrane transporter activity",PF02535;,,,,,,,,,FOI_DROME,Drosophila melanogaster (Fruit fly),"branch fusion, open tracheal system [GO:0035147]; cell migration [GO:0016477]; cellular zinc ion homeostasis [GO:0006882]; central nervous system development [GO:0007417]; germ cell migration [GO:0008354]; gonadal mesoderm development [GO:0007506]; gonad development [GO:0008406]; gonad morphogenesis [GO:0035262]; neurogenesis [GO:0022008]; pole cell migration [GO:0007280]; zinc II ion transmembrane import [GO:0071578]; zinc II ion transport [GO:0006829]" comp142172_c0_seq2,2573,41.0805,0.46095665,5,33,,1.00E-57,Q9ULF5,Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10),Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10),GO:0016021; GO:0046873; GO:0055085; GO:0006829,integral to membrane; metal ion transmembrane transporter activity; transmembrane transport; zinc ion transport,PF02535;,,,,,,,,,S39AA_HUMAN,Homo sapiens (Human),cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc II ion transmembrane import [GO:0071578] comp142172_c0_seq3,2732,41.6179,0.48269768,0,0,,1.00E-57,Q9ULF5,Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10),Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10),GO:0016021; GO:0046873; GO:0055085; GO:0006829,integral to membrane; metal ion transmembrane transporter activity; transmembrane transport; zinc ion transport,PF02535;,2.00E-61,CHOYP_S39AA.1.3,,,,,,,S39AA_HUMAN,Homo sapiens (Human),cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc II ion transmembrane import [GO:0071578] comp142172_c0_seq4,2071,40.9947,0.52972312,16,32,,1.00E-55,Q9VSL7,Zinc transporter foi (Protein fear-of-intimacy) (Protein kastchen),Zinc transporter foi (Protein fear-of-intimacy) (Protein kastchen),GO:0035147; GO:0009986; GO:0007417; GO:0035262; GO:0007506; GO:0005887; GO:0022008; GO:0007280; GO:0005385,"branch fusion, open tracheal system; cell surface; central nervous system development; gonad morphogenesis; gonadal mesoderm development; integral to plasma membrane; neurogenesis; pole cell migration; zinc ion transmembrane transporter activity",PF02535;,8.00E-15,CHOYP_S39AA.3.3,7.00E-39,ruditapes_c13820,,,,,FOI_DROME,Drosophila melanogaster (Fruit fly),"branch fusion, open tracheal system [GO:0035147]; cell migration [GO:0016477]; cellular zinc ion homeostasis [GO:0006882]; central nervous system development [GO:0007417]; germ cell migration [GO:0008354]; gonadal mesoderm development [GO:0007506]; gonad development [GO:0008406]; gonad morphogenesis [GO:0035262]; neurogenesis [GO:0022008]; pole cell migration [GO:0007280]; zinc II ion transmembrane import [GO:0071578]; zinc II ion transport [GO:0006829]" comp142172_c0_seq6,2592,41.1651,0.48315645,0,0,,,,,,,,,2.00E-61,CHOYP_S39AA.1.3,,,,,,,,, comp142174_c0_seq1,952,34.4538,0.42533613,1129,2728,,2.00E-15,Q2KIN1,Dolichol phosphate-mannose biosynthesis regulatory protein,Dolichol phosphate-mannose biosynthesis regulatory protein (Dolichol-phosphate mannose synthase subunit 2) (DPM synthase subunit 2),GO:0030176; GO:0009059,integral to endoplasmic reticulum membrane; macromolecule biosynthetic process,PF07297;,,,4.00E-13,ruditapes_c20349,,,,,DPM2_BOVIN,Bos taurus (Bovine),dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein O-linked mannosylation [GO:0035269] comp142174_c1_seq1,1566,39.9745,0.59530997,164,609,,1.00E-98,Q12972,Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)],Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)],GO:0003677; GO:0003723; GO:0006401; GO:0008380; GO:0008283; GO:0005737; GO:0004519; GO:0006397; GO:0016607; GO:0008599; GO:0004865; GO:0006355; GO:0008995; GO:0005681; GO:0006351,"DNA binding; RNA binding; RNA catabolic process; RNA splicing; cell proliferation; cytoplasm; endonuclease activity; mRNA processing; nuclear speck; protein phosphatase type 1 regulator activity; protein serine/threonine phosphatase inhibitor activity; regulation of transcription, DNA-dependent; ribonuclease E activity; spliceosomal complex; transcription, DNA-dependent",PF00498;,4.00E-93,CHOYP_LOC100113671.1.1,,,,,,,PP1R8_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA catabolic process [GO:0006401]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142175_c0_seq1,1269,44.9173,0.28380258,80,33,,7.00E-10,O60229,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0015629; GO:0097190; GO:0005829; GO:0005085; GO:0046872; GO:0007399; GO:0048011; GO:0005543; GO:0043065; GO:0004674; GO:0035023; GO:0051056; GO:0007264; GO:0016192,ATP binding; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton; apoptotic signaling pathway; cytosol; guanyl-nucleotide exchange factor activity; metal ion binding; nervous system development; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; vesicle-mediated transport,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;,,,,,,,,,KALRN_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp142175_c1_seq1,2441,44.6538,0.4193207,162,168,,5.00E-22,A2AAJ9,Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),GO:0005524; GO:0031430; GO:0005089; GO:0030154; GO:0007275; GO:0018108; GO:0005543; GO:0004674; GO:0004713; GO:0035023,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; cell differentiation; multicellular organismal development; peptidyl-tyrosine phosphorylation; phospholipid binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of Rho protein signal transduction,PF00041;PF07679;PF00612;PF00069;PF00621;,,,,,,,,,OBSCN_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023] comp142175_c2_seq1,2551,48.922,0.57683139,2,0,,1.00E-36,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,8.00E-111,CHOYP_TITIN.18.19,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp142175_c2_seq10,2088,49.1379,0.5794841,8,0,,5.00E-37,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp142175_c2_seq2,3332,48.7995,0.5698445,1,0,,1.00E-56,Q9I7U4,Titin (D-Titin) (Kettin),Titin (D-Titin) (Kettin),GO:0030018; GO:0003779; GO:0051301; GO:0000794; GO:0040011; GO:0007498; GO:0005875; GO:0007076; GO:0016203; GO:0007520; GO:0035206; GO:0045214; GO:0007062; GO:0007519; GO:0007525; GO:0008307; GO:0007522,Z disc; actin binding; cell division; condensed nuclear chromosome; locomotion; mesoderm development; microtubule associated complex; mitotic chromosome condensation; muscle attachment; myoblast fusion; regulation of hemocyte proliferation; sarcomere organization; sister chromatid cohesion; skeletal muscle tissue development; somatic muscle development; structural constituent of muscle; visceral muscle development,PF06582;PF00041;PF07679;PF00018;,1.00E-110,CHOYP_TITIN.18.19,,,,,,,TITIN_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522] comp142175_c2_seq7,989,48.0283,0.59680912,2,0,,2.00E-22,A2AAJ9,Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),GO:0005524; GO:0031430; GO:0005089; GO:0030154; GO:0007275; GO:0018108; GO:0005543; GO:0004674; GO:0004713; GO:0035023,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; cell differentiation; multicellular organismal development; peptidyl-tyrosine phosphorylation; phospholipid binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of Rho protein signal transduction,PF00041;PF07679;PF00612;PF00069;PF00621;,6.00E-57,CHOYP_LOC100169177.1.1,,,,,,,OBSCN_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023] comp142175_c2_seq9,1251,48.5212,0.59852276,6,10,,4.00E-60,Q9I7U4,Titin (D-Titin) (Kettin),Titin (D-Titin) (Kettin),GO:0030018; GO:0003779; GO:0051301; GO:0000794; GO:0040011; GO:0007498; GO:0005875; GO:0007076; GO:0016203; GO:0007520; GO:0035206; GO:0045214; GO:0007062; GO:0007519; GO:0007525; GO:0008307; GO:0007522,Z disc; actin binding; cell division; condensed nuclear chromosome; locomotion; mesoderm development; microtubule associated complex; mitotic chromosome condensation; muscle attachment; myoblast fusion; regulation of hemocyte proliferation; sarcomere organization; sister chromatid cohesion; skeletal muscle tissue development; somatic muscle development; structural constituent of muscle; visceral muscle development,PF06582;PF00041;PF07679;PF00018;,,,,,,,,,TITIN_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522] comp142178_c0_seq1,729,39.6433,0.5561209,48,198,,7.00E-106,Q05976,Ras-related protein Rab-18A,Ras-related protein Rab-18A,GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,2.00E-111,CHOYP_RB18B.1.1,4.00E-24,ruditapes_c7176,,,,,RB18A_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp142181_c0_seq10,4362,43.2829,0.3628874,0,0,,,,,,,,,2.00E-14,CHOYP_PSMD2.3.3,,,,,,,,, comp142181_c0_seq11,2264,40.8127,0.26954023,0,0,,2.00E-23,Q99PP2,Zinc finger protein 318 (Testicular zinc finger protein) (Fragment),Zinc finger protein 318 (Testicular zinc finger protein) (Fragment),GO:0007126; GO:0003676; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"meiosis; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,ZN318_MOUSE,Mus musculus (Mouse),"meiotic cell cycle [GO:0051321]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142181_c0_seq12,3274,41.9059,0.31064607,0,0,,,,,,,,,1.00E-14,CHOYP_PSMD2.3.3,,,,,,,,, comp142181_c0_seq2,1529,39.2413,0.28946326,0,0,,4.00E-24,Q99PP2,Zinc finger protein 318 (Testicular zinc finger protein) (Fragment),Zinc finger protein 318 (Testicular zinc finger protein) (Fragment),GO:0007126; GO:0003676; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"meiosis; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,ZN318_MOUSE,Mus musculus (Mouse),"meiotic cell cycle [GO:0051321]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142181_c0_seq7,1270,39.685,0.28022065,0,0,,1.00E-18,Q99PP2,Zinc finger protein 318 (Testicular zinc finger protein) (Fragment),Zinc finger protein 318 (Testicular zinc finger protein) (Fragment),GO:0007126; GO:0003676; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"meiosis; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,ZN318_MOUSE,Mus musculus (Mouse),"meiotic cell cycle [GO:0051321]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142181_c0_seq8,3015,42.3217,0.30770919,0,0,,,,,,,,,1.00E-14,CHOYP_PSMD2.3.3,,,,,,,,, comp142182_c0_seq1,5292,41.1754,0.54880858,5758,47,,3.00E-139,A4FU69,EF-hand calcium-binding domain-containing protein 5,EF-hand calcium-binding domain-containing protein 5,GO:0005509,calcium ion binding,,0,CHOYP_NEMVEDRAFT_V1G167853.2.2,,,,,,,EFCB5_HUMAN,Homo sapiens (Human), comp142183_c0_seq1,7515,44.0452,0.65267345,10,3,,0,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,,,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp142183_c0_seq10,7126,44.5411,0.65583592,0,0,,8.00E-118,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,2.00E-15,CHOYP_CADN.1.3,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp142183_c0_seq11,9592,44.2765,0.65910005,40,87,,0,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,7.00E-17,CHOYP_CADN.2.3,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp142183_c0_seq12,9210,44.6688,0.65651426,2,0,,0,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,3.00E-15,CHOYP_CADN.1.3,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp142183_c0_seq13,2426,45.6719,0.76464289,0,7,,4.00E-55,O93319,Cadherin-11,Cadherin-11,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;,6.00E-11,CHOYP_CADN.2.3,,,,,,,CAD11_CHICK,Gallus gallus (Chicken),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp142183_c0_seq2,7551,44.0471,0.65222328,0,0,,4.00E-77,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,2.00E-15,CHOYP_CADN.1.3,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp142183_c0_seq3,2481,45.6671,0.7548521,0,0,,5.00E-55,O93319,Cadherin-11,Cadherin-11,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;,,,2.00E-28,ruditapes_c13441,,,,,CAD11_CHICK,Gallus gallus (Chicken),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp142183_c0_seq4,8676,44.894,0.65509623,0,0,,0,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,2.00E-23,CHOYP_CADN.1.3,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp142183_c0_seq8,7160,44.4413,0.65564448,0,0,,0,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,2.00E-23,CHOYP_CADN.1.3,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp142185_c2_seq1,627,42.1053,0.87222444,34,104,,7.00E-75,Q2KID4,"Dynein light chain 1, axonemal","Dynein light chain 1, axonemal",,,,3.00E-40,CHOYP_DNAL1.1.1,,,,,,,DNAL1_BOVIN,Bos taurus (Bovine), comp142188_c0_seq1,2822,37.8455,0.4273253,0,0,,1.00E-59,Q6AX31,Nucleoporin NDC1 (xNDC1) (Transmembrane protein 48),Nucleoporin NDC1 (xNDC1) (Transmembrane protein 48),GO:0051028; GO:0031965; GO:0005643; GO:0015031,mRNA transport; nuclear membrane; nuclear pore; protein transport,PF09531;,2.00E-11,CHOYP_NDC1.1.1,,,,,,,NDC1_XENLA,Xenopus laevis (African clawed frog),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp142188_c0_seq2,2845,37.8207,0.42481304,0,0,,1.00E-59,Q6AX31,Nucleoporin NDC1 (xNDC1) (Transmembrane protein 48),Nucleoporin NDC1 (xNDC1) (Transmembrane protein 48),GO:0051028; GO:0031965; GO:0005643; GO:0015031,mRNA transport; nuclear membrane; nuclear pore; protein transport,PF09531;,,,,,,,,,NDC1_XENLA,Xenopus laevis (African clawed frog),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp142188_c0_seq4,2840,37.8521,0.4343675,0,0,,4.00E-16,Q8I4N3,Nucleoporin ndc-1 (Nucleoporin npp-22),Nucleoporin ndc-1 (Nucleoporin npp-22),GO:0051028; GO:0031965; GO:0005643; GO:0015031,mRNA transport; nuclear membrane; nuclear pore; protein transport,PF09531;,2.00E-11,CHOYP_NDC1.1.1,,,,,,,NDC1_CAEEL,Caenorhabditis elegans,mRNA transport [GO:0051028]; nuclear pore organization [GO:0006999]; protein transport [GO:0015031] comp142190_c2_seq4,2440,39.959,0.8736212,0,20,,3.00E-24,Q96B70,Leukocyte receptor cluster member 9,Leukocyte receptor cluster member 9,GO:0003824; GO:0008152; GO:0046872,catalytic activity; metabolic process; metal ion binding,PF10469;PF04457;,,,,,,,,,LENG9_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp142191_c0_seq2,3348,44.7431,0.48744506,238,357,,0,Q15155,Nodal modulator 1 (pM5 protein),Nodal modulator 1 (pM5 protein),GO:0030246; GO:0016021,carbohydrate binding; integral to membrane,,3.00E-55,CHOYP_NOMO1.2.2,,,,,,,NOMO1_HUMAN,Homo sapiens (Human), comp142194_c1_seq2,1814,48.8423,0.77793236,1,0,,,,,,,,,1.00E-50,CHOYP_ENS.3.3,3.00E-37,ruditapes_c14395,,,,,,, comp142195_c0_seq1,3345,39.8505,0.27226866,2542,648,,7.00E-152,Q8IYF3,Testis-expressed sequence 11 protein,Testis-expressed sequence 11 protein,GO:0000801; GO:0051026; GO:0009566; GO:0008584; GO:0007060; GO:0006311; GO:0043066; GO:0007131; GO:0000712; GO:0007130,central element; chiasma assembly; fertilization; male gonad development; male meiosis chromosome segregation; meiotic gene conversion; negative regulation of apoptotic process; reciprocal meiotic recombination; resolution of meiotic recombination intermediates; synaptonemal complex assembly,PF08631;,,,,,,,,,TEX11_HUMAN,Homo sapiens (Human),chiasma assembly [GO:0051026]; fertilization [GO:0009566]; male gonad development [GO:0008584]; male meiosis chromosome segregation [GO:0007060]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; synaptonemal complex assembly [GO:0007130] comp142200_c0_seq1,1792,38.7277,0.45619941,70,354,,3.00E-87,Q5AW89,Actin-related protein 4 (Actin-like protein arp4) (Actin-like protein 4),Actin-related protein 4 (Actin-like protein arp4) (Actin-like protein 4),GO:0006281; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA repair; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00022;,1.00E-169,CHOYP_ACL6B.1.1,,,,,,,ARP4_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),"chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142200_c0_seq2,1764,38.8889,0.46024283,39,117,,0,O96019,Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K),Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K),GO:0006310; GO:0006281; GO:0031011; GO:0035267; GO:0016514; GO:0003682; GO:0006338; GO:0043968; GO:0043967; GO:0007399; GO:0003407; GO:0071564; GO:0005886; GO:0040008; GO:0006357; GO:0007165; GO:0003713; GO:0006351,"DNA recombination; DNA repair; Ino80 complex; NuA4 histone acetyltransferase complex; SWI/SNF complex; chromatin binding; chromatin remodeling; histone H2A acetylation; histone H4 acetylation; nervous system development; neural retina development; npBAF complex; plasma membrane; regulation of growth; regulation of transcription from RNA polymerase II promoter; signal transduction; transcription coactivator activity; transcription, DNA-dependent",PF00022;,,,7.00E-76,ruditapes2_c1766,,,,,ACL6A_HUMAN,Homo sapiens (Human),"ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; neural retina development [GO:0003407]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of growth [GO:0040008]; regulation of mitophagy [GO:1903146]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; transcription, DNA-templated [GO:0006351]" comp142203_c0_seq1,1994,38.2146,0.61446077,46,74,,4.00E-149,P49411,"Elongation factor Tu, mitochondrial (EF-Tu) (P43)","Elongation factor Tu, mitochondrial (EF-Tu) (P43)",GO:0005525; GO:0006184; GO:0003924; GO:0042645; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; mitochondrial nucleoid; translation elongation factor activity,PF03144;PF03143;,8.00E-59,CHOYP_LOC658895.1.1,,,,,,,EFTU_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414] comp142203_c0_seq2,1787,37.6609,0.56489339,35,106,,4.00E-61,Q93PU8,Elongation factor Tu (EF-Tu) (Fragment),Elongation factor Tu (EF-Tu) (Fragment),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,,,,,,,,,EFTU_STAWA,Staphylococcus warneri, comp142204_c0_seq1,1657,38.0205,0.40695037,39,268,,7.00E-68,O94826,Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit),Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70),GO:0044267; GO:0016021; GO:0005742; GO:0006626; GO:0008320,cellular protein metabolic process; integral to membrane; mitochondrial outer membrane translocase complex; protein targeting to mitochondrion; protein transmembrane transporter activity,PF00515;PF13181;,,,,,,,,,TOM70_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; protein targeting to mitochondrion [GO:0006626] comp142204_c0_seq3,1480,37.7703,0.42115215,1,0,,3.00E-18,O14217,Probable mitochondrial import receptor subunit tom70 (Translocase of outer membrane 40 kDa subunit),Probable mitochondrial import receptor subunit tom70 (Translocase of outer membrane 40 kDa subunit),GO:0016021; GO:0005742; GO:0045039; GO:0008565,integral to membrane; mitochondrial outer membrane translocase complex; protein import into mitochondrial inner membrane; protein transporter activity,,,,,,,,,,TOM70_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein import into mitochondrial matrix [GO:0030150] comp142204_c0_seq5,1012,43.6759,0.60179098,5,41,,3.00E-12,Q9H6T3,RNA polymerase II-associated protein 3,RNA polymerase II-associated protein 3,,,PF13877;PF00515;PF13176;PF13181;,,,,,,,,,RPAP3_HUMAN,Homo sapiens (Human), comp142204_c0_seq7,1066,43.8086,0.5679704,11,29,,3.00E-57,O94826,Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit),Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70),GO:0044267; GO:0016021; GO:0005742; GO:0006626; GO:0008320,cellular protein metabolic process; integral to membrane; mitochondrial outer membrane translocase complex; protein targeting to mitochondrion; protein transmembrane transporter activity,PF00515;PF13181;,,,,,,,,,TOM70_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; protein targeting to mitochondrion [GO:0006626] comp142205_c0_seq2,1190,39.4958,0.41654884,0,0,,6.00E-67,Q4V8V2,Nucleoside diphosphate-linked moiety X motif 17 (Nudix motif 17) (EC 3.6.1.-),Nucleoside diphosphate-linked moiety X motif 17 (Nudix motif 17) (EC 3.6.1.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF00293;,,,,,,,,,NUD17_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142205_c0_seq7,1364,38.8563,0.41422834,0,0,,,,,,,,,2.00E-19,CHOYP_NUD17.1.1,,,,,,,,, comp142206_c0_seq1,2000,38.1,0.38677749,1342,985,,2.00E-88,Q5R514,Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)],Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)],GO:0044205; GO:0006207; GO:0004588; GO:0004590,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; orotate phosphoribosyltransferase activity; orotidine-5'-phosphate decarboxylase activity,PF00215;PF00156;,3.00E-33,CHOYP_LOC100367421.1.1,,,,,,,UMPS_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205] comp142211_c0_seq1,1804,39.2461,0.44754347,6,31,,5.00E-77,Q28FD1,Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1),Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1),GO:0008106,alcohol dehydrogenase (NADP+) activity,PF00248;,2.00E-78,CHOYP_ALDR.1.1,,,,,,,AK1A1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142211_c0_seq2,1771,39.4128,0.45248406,19,83,,1.00E-94,P82125,"1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member CL2) (Aldo-keto reductase family 1 member E2)","1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member CL2) (Aldo-keto reductase family 1 member E2)",GO:0050571,"1,5-anhydro-D-fructose reductase activity",PF00248;,5.00E-80,CHOYP_ALDR.1.1,3.00E-55,ruditapes_c19542,,,,,AKCL2_PIG,Sus scrofa (Pig), comp142212_c1_seq1,4213,40.0665,0.51254166,174,125,,8.00E-177,Q9NQI0,Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog),Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog),GO:0005524; GO:0008026; GO:0033391; GO:0007141; GO:0007275; GO:0003676; GO:0005634; GO:0048471; GO:0071546; GO:0071547; GO:0032880; GO:0030317; GO:0007283,ATP binding; ATP-dependent helicase activity; chromatoid body; male meiosis I; multicellular organismal development; nucleic acid binding; nucleus; perinuclear region of cytoplasm; pi-body; piP-body; regulation of protein localization; sperm motility; spermatogenesis,PF00270;PF00271;,,,,,,,,,DDX4_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp142212_c1_seq2,4191,40.062,0.50924738,200,713,,7.00E-177,Q9NQI0,Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog),Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog),GO:0005524; GO:0008026; GO:0033391; GO:0007141; GO:0007275; GO:0003676; GO:0005634; GO:0048471; GO:0071546; GO:0071547; GO:0032880; GO:0030317; GO:0007283,ATP binding; ATP-dependent helicase activity; chromatoid body; male meiosis I; multicellular organismal development; nucleic acid binding; nucleus; perinuclear region of cytoplasm; pi-body; piP-body; regulation of protein localization; sperm motility; spermatogenesis,PF00270;PF00271;,4.00E-161,CHOYP_LOC100370637.2.2,,,,,,,DDX4_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp142213_c0_seq1,2743,42.8728,0.53092347,429,1142,,0,Q7ZY47,ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42),ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; nucleus,PF00270;PF00271;,0,CHOYP_DDX42.2.2,,,,,,,DDX42_XENLA,Xenopus laevis (African clawed frog), comp142214_c0_seq1,2218,42.4707,0.43223626,37,99,,1.00E-105,Q16401,26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B),26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B),GO:0006977; GO:0000082; GO:0031145; GO:0002479; GO:0006915; GO:0005829; GO:0010467; GO:0016071; GO:0043066; GO:0051436; GO:0005654; GO:0051437; GO:0022624; GO:0070682; GO:0006457; GO:0000209; GO:0006521; GO:0044281; GO:0016032,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; G1/S transition of mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; apoptotic process; cytosol; gene expression; mRNA metabolic process; negative regulation of apoptotic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; proteasome accessory complex; proteasome regulatory particle assembly; protein folding; protein polyubiquitination; regulation of cellular amino acid metabolic process; small molecule metabolic process; viral process",PF10508;,,,,,,,,,PSMD5_HUMAN,Homo sapiens (Human),"anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteasome regulatory particle assembly [GO:0070682]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp142214_c0_seq4,2224,41.4568,0.46161835,95,263,,4.00E-107,Q0P5A6,26S proteasome non-ATPase regulatory subunit 5,26S proteasome non-ATPase regulatory subunit 5,GO:0022624; GO:0008540; GO:0006457,"proteasome accessory complex; proteasome regulatory particle, base subcomplex; protein folding",PF10508;,,,,,,,,,PSMD5_BOVIN,Bos taurus (Bovine),proteasome regulatory particle assembly [GO:0070682] comp142216_c0_seq1,4155,42.1179,0.54263821,8011,866,,0,Q5T2S8,Armadillo repeat-containing protein 4,Armadillo repeat-containing protein 4,,,PF00514;,0,CHOYP_BRAFLDRAFT_126603.1.1,,,,,,,ARMC4_HUMAN,Homo sapiens (Human),cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] comp142222_c0_seq1,1542,42.0882,0.54503212,10,32,,3.00E-58,Q5JHP2,Replication factor C small subunit (RFC small subunit) (Clamp loader small subunit) [Cleaved into: Pko RFC intein],Replication factor C small subunit (RFC small subunit) (Clamp loader small subunit) [Cleaved into: Pko RFC intein],GO:0005524; GO:0006310; GO:0006281; GO:0006260; GO:0004519; GO:0009378; GO:0016539; GO:0043565,ATP binding; DNA recombination; DNA repair; DNA replication; endonuclease activity; four-way junction helicase activity; intein-mediated protein splicing; sequence-specific DNA binding,PF01381;PF14528;PF08542;PF05496;,,,,,,,,,RFCS_PYRKO,Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539] comp142222_c0_seq2,1957,40.7767,0.51969174,284,1162,,2.00E-163,Q99J62,Replication factor C subunit 4 (Activator 1 subunit 4),Replication factor C subunit 4 (Activator 1 subunit 4),GO:0005524; GO:0003677; GO:0006260; GO:0005663; GO:0017111; GO:0005634,ATP binding; DNA binding; DNA replication; DNA replication factor C complex; nucleoside-triphosphatase activity; nucleus,PF00004;PF08542;,8.00E-116,CHOYP_BRAFLDRAFT_284971.1.1,6.00E-33,ruditapes_c12577,1.00E-88,AM859623.p.cg.6,8,,RFC4_MOUSE,Mus musculus (Mouse),DNA-dependent DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] comp142223_c0_seq1,2402,37.8018,1.03854332,180,865,,6.00E-25,P12812,Major egg antigen (p40),Major egg antigen (p40),,,PF00011;,2.00E-30,CHOYP_SMP_148530.1.1,,,,,,,P40_SCHMA,Schistosoma mansoni (Blood fluke), comp142224_c0_seq1,3644,35.3732,0.51443217,674,1965,,2.00E-68,Q75G68,Probable protein arginine N-methyltransferase 6.2 (EC 2.1.1.-),Probable protein arginine N-methyltransferase 6.2 (EC 2.1.1.-),GO:0008168; GO:0006479,methyltransferase activity; protein methylation,,,,,,,,,,ANM62_ORYSJ,Oryza sativa subsp. japonica (Rice),"regulation of transcription, DNA-templated [GO:0006355]" comp142224_c0_seq2,3625,35.3931,0.51711865,299,1746,,4.00E-180,Q63009,Protein arginine N-methyltransferase 1 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT1) (EC 2.1.1.125),Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1),GO:0016275; GO:0005829; GO:0044020; GO:0001701; GO:0045653; GO:0031175; GO:0005654; GO:0005634; GO:0043234; GO:0035242; GO:0035241; GO:0030519,[cytochrome c]-arginine N-methyltransferase activity; cytosol; histone methyltransferase activity (H4-R3 specific); in utero embryonic development; negative regulation of megakaryocyte differentiation; neuron projection development; nucleoplasm; nucleus; protein complex; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; snoRNP binding,,3.00E-156,CHOYP_ISCW_ISCW023973.1.2,,,,,,,ANM1_RAT,Rattus norvegicus (Rat),"histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein methylation [GO:0006479]; regulation of transcription, DNA-templated [GO:0006355]" comp142225_c0_seq3,2233,42.3197,0.41500466,326,1650,,2.00E-178,Q5F3D7,U3 small nucleolar RNA-associated protein 15 homolog,U3 small nucleolar RNA-associated protein 15 homolog,GO:0005737; GO:0005730; GO:0006364,cytoplasm; nucleolus; rRNA processing,PF09384;PF00400;,1.00E-64,CHOYP_UTP15.1.1,,,,,,,UTP15_CHICK,Gallus gallus (Chicken),rRNA processing [GO:0006364] comp142226_c0_seq1,943,43.0541,0.32297202,127,159,,7.00E-51,Q3KRD5,Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit),Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit),GO:0005741; GO:0006626,mitochondrial outer membrane; protein targeting to mitochondrion,PF00515;PF13181;,,,2.00E-15,ruditapes_c17813,,,,,TOM34_RAT,Rattus norvegicus (Rat),protein targeting to mitochondrion [GO:0006626] comp142226_c0_seq2,1013,34.4521,0.33600669,174,415,,6.00E-08,Q9H6T3,RNA polymerase II-associated protein 3,RNA polymerase II-associated protein 3,,,PF13877;PF00515;PF13176;PF13181;,,,2.00E-41,ruditapes_c11413,,,,,RPAP3_HUMAN,Homo sapiens (Human), comp142228_c0_seq2,2356,41.893,0.37940506,162,585,,0,Q7T322,"N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein) (zEGAP) (Protein MAK10 homolog)","N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein) (zEGAP) (Protein MAK10 homolog)",GO:0048514; GO:0005737; GO:0043066; GO:0008284; GO:0032006; GO:0048659; GO:0001756,blood vessel morphogenesis; cytoplasm; negative regulation of apoptotic process; positive regulation of cell proliferation; regulation of TOR signaling cascade; smooth muscle cell proliferation; somitogenesis,PF04112;,7.00E-137,CHOYP_NAA35.1.1,,,,,,,NAA35_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),blood vessel morphogenesis [GO:0048514]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell proliferation [GO:0008284]; regulation of TOR signaling [GO:0032006]; smooth muscle cell proliferation [GO:0048659]; somitogenesis [GO:0001756] comp142230_c1_seq1,2583,42.741,0.93303585,61,2913,,6.00E-53,Q27319,"Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)","Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)",GO:0051693; GO:0005737; GO:0005856; GO:0046872,actin filament capping; cytoplasm; cytoskeleton; metal ion binding,PF00626;,,,,,,,,,GELS_HOMAM,Homarus americanus (American lobster),actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016] comp142230_c1_seq2,2200,43.2727,0.95259524,0,331,female,9.00E-131,Q8MPM1,Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2),Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2),GO:0051693; GO:0005737; GO:0005856,actin filament capping; cytoplasm; cytoskeleton,PF00626;,2.00E-79,CHOYP_LOC100371249.1.1,,,7.00E-74,AJ563467.p.cg.6,4,,GELS2_LUMTE,Lumbricus terrestris (Common earthworm),actin filament capping [GO:0051693] comp142232_c0_seq1,2445,38.1595,0.34484385,158,819,,1.00E-111,Q6DC64,Methyltransferase-like protein 16 (EC 2.1.1.-) (Methyltransferase 10 domain-containing protein),Methyltransferase-like protein 16 (EC 2.1.1.-) (Methyltransferase 10 domain-containing protein),GO:0008168,methyltransferase activity,PF05971;,,,,,,,,,MET16_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),rRNA base methylation [GO:0070475] comp142234_c0_seq2,1696,45.5778,0.44429467,0,2,,,,,,,,,6.00E-47,CHOYP_CNKR2.3.3,,,,,,,,, comp142234_c0_seq4,1224,36.683,0.51084271,2,47,,4.00E-11,Q8WWN9,Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E),Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E),GO:0005737; GO:0005344; GO:0004601; GO:0005543; GO:0005886; GO:0006979,cytoplasm; oxygen transporter activity; peroxidase activity; phospholipid binding; plasma membrane; response to oxidative stress,PF00169;,9.00E-12,CHOYP_CNKR2.2.3,,,,,,,ICEF1_HUMAN,Homo sapiens (Human),oxygen transport [GO:0015671]; response to oxidative stress [GO:0006979] comp142234_c0_seq5,2170,45.576,0.49732889,0,0,,2.00E-36,Q80YA9,Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2),Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2),GO:0005737; GO:0043005; GO:0043025; GO:0005543; GO:0045211; GO:0009966,cytoplasm; neuron projection; neuronal cell body; phospholipid binding; postsynaptic membrane; regulation of signal transduction,PF10534;PF06663;PF00595;PF00169;PF00536;,8.00E-47,CHOYP_LOC100748006.2.2,,,,,,,CNKR2_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; regulation of signal transduction [GO:0009966] comp142234_c0_seq6,1877,46.0309,0.46293848,7,17,,,,,,,,,7.00E-47,CHOYP_CNKR2.3.3,,,,,,,,, comp142234_c0_seq7,2215,45.4628,0.46330581,10,95,,3.00E-36,Q80YA9,Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2),Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2),GO:0005737; GO:0043005; GO:0043025; GO:0005543; GO:0045211; GO:0009966,cytoplasm; neuron projection; neuronal cell body; phospholipid binding; postsynaptic membrane; regulation of signal transduction,PF10534;PF06663;PF00595;PF00169;PF00536;,8.00E-47,CHOYP_LOC100748006.2.2,,,,,,,CNKR2_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; regulation of signal transduction [GO:0009966] comp142235_c0_seq1,1374,36.3901,0.87721497,8,229,,,,,,,,,,,1.00E-13,ruditapes_c6210,,,,,,, comp142235_c0_seq4,1389,35.9251,0.82243156,0,15,,2.00E-15,Q148C8,Migration and invasion enhancer 1,Migration and invasion enhancer 1,GO:0006915; GO:0045454; GO:0005829; GO:0031235; GO:0043066; GO:0030335; GO:0051491; GO:0008430,apoptotic process; cell redox homeostasis; cytosol; intrinsic to internal side of plasma membrane; negative regulation of apoptotic process; positive regulation of cell migration; positive regulation of filopodium assembly; selenium binding,PF10262;,,,4.00E-14,ruditapes_c840,,,,,MIEN1_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell migration [GO:0030335]; positive regulation of filopodium assembly [GO:0051491] comp142236_c0_seq1,1311,38.6728,0.98237352,20,124,,1.00E-14,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp142236_c0_seq2,1300,39,0.99483517,15,93,,6.00E-09,P98087,Cerebellin-2 (Cerebellin-like protein),Cerebellin-2 (Cerebellin-like protein),GO:0005615; GO:0051965,extracellular space; positive regulation of synapse assembly,PF00386;,,,,,,,,,CBLN2_RAT,Rattus norvegicus (Rat),positive regulation of synapse assembly [GO:0051965] comp142238_c0_seq1,1801,39.7002,0.48692654,3,0,,1.00E-120,Q32NQ7,"Dynein assembly factor 3, axonemal","Dynein assembly factor 3, axonemal",GO:0070286; GO:0005737; GO:0044458,axonemal dynein complex assembly; cytoplasm; motile cilium assembly,PF14737;PF14740;,2.00E-78,CHOYP_LOC100377462.1.1,,,,,,,DAAF3_XENLA,Xenopus laevis (African clawed frog),axonemal dynein complex assembly [GO:0070286]; motile cilium assembly [GO:0044458] comp142238_c0_seq2,1872,40.1175,0.4610029,24,49,,1.00E-120,Q32NQ7,"Dynein assembly factor 3, axonemal","Dynein assembly factor 3, axonemal",GO:0070286; GO:0005737; GO:0044458,axonemal dynein complex assembly; cytoplasm; motile cilium assembly,PF14737;PF14740;,,,2.00E-14,ruditapes_c20357,,,,,DAAF3_XENLA,Xenopus laevis (African clawed frog),axonemal dynein complex assembly [GO:0070286]; motile cilium assembly [GO:0044458] comp142240_c0_seq1,2542,40.3619,0.38047108,1009,15861,,8.00E-125,Q8VCY6,U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein),U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein),GO:0005730; GO:0006364,nucleolus; rRNA processing,PF08640;,1.00E-51,CHOYP_BRAFLDRAFT_92084.1.1,,,,,,,UTP6_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp142241_c0_seq1,3518,38.9994,0.51309369,170,12,,0,Q16959,"Dynein intermediate chain 2, ciliary","Dynein intermediate chain 2, ciliary",GO:0035085; GO:0030286; GO:0005874; GO:0003774,cilium axoneme; dynein complex; microtubule; motor activity,PF00400;,0,CHOYP_LOC100368022.1.1,,,,,,,DYI2_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina), comp142241_c0_seq2,3506,38.9333,0.48517342,137,11,,7.00E-57,Q4V8G4,WD repeat-containing protein 78,WD repeat-containing protein 78,,,PF00400;,0,CHOYP_LOC100368022.1.1,,,,,,,WDR78_RAT,Rattus norvegicus (Rat),hematopoietic progenitor cell differentiation [GO:0002244] comp142242_c0_seq1,2207,37.2451,0.4386439,297,1365,,1.00E-47,Q5RCY5,Protein asteroid homolog 1,Protein asteroid homolog 1,GO:0006281; GO:0004518; GO:0090305,DNA repair; nuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00752;,,,,,,,,,ASTE1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),DNA repair [GO:0006281] comp142242_c1_seq1,690,39.5652,0.74461363,17,112,,3.00E-18,Q9VPW1,Protein asteroid,Protein asteroid,GO:0001752; GO:0007173; GO:0008586; GO:0007526,compound eye photoreceptor fate commitment; epidermal growth factor receptor signaling pathway; imaginal disc-derived wing vein morphogenesis; larval somatic muscle development,,1.00E-13,CHOYP_ISCW_ISCW000775.1.1,,,,,,,ASTE_DROME,Drosophila melanogaster (Fruit fly),compound eye morphogenesis [GO:0001745]; compound eye photoreceptor fate commitment [GO:0001752]; epidermal growth factor receptor signaling pathway [GO:0007173]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; larval somatic muscle development [GO:0007526] comp142247_c0_seq13,717,39.3305,0.93917776,15,0,,6.00E-16,Q9C0I9,Leucine-rich repeat-containing protein 27,Leucine-rich repeat-containing protein 27,,,PF13855;,,,,,,,,,LRC27_HUMAN,Homo sapiens (Human), comp142247_c0_seq14,1340,36.5672,0.49360064,0,0,,,,,,,,,5.00E-41,CHOYP_contig_023120,,,,,,,,, comp142247_c0_seq3,413,39.9516,0.92000539,17,9,,6.00E-17,Q9C0I9,Leucine-rich repeat-containing protein 27,Leucine-rich repeat-containing protein 27,,,PF13855;,,,,,,,,,LRC27_HUMAN,Homo sapiens (Human), comp142247_c0_seq4,1319,36.467,0.50416696,0,0,,,,,,,,,5.00E-41,CHOYP_contig_023120,,,,,,,,, comp142248_c0_seq1,1961,37.1239,0.55243647,1003,2739,,,,,,,,,0,CHOYP_PSMD6.1.1,,,,,,,,, comp142248_c0_seq2,1945,37.1208,0.57221137,358,1026,,0,Q99JI4,26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (p42A),26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (p42A),GO:0022624,proteasome accessory complex,PF01399;PF10602;,,,8.00E-95,ruditapes_c25351,,,,,PSMD6_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp142249_c0_seq1,936,46.4744,0.46049198,0,3,,7.00E-48,Q75J93,Circularly permutated Ras protein 1 (DdiCPRas1),Circularly permutated Ras protein 1 (DdiCPRas1),GO:0030127; GO:0006888; GO:0005525; GO:0003924; GO:0006886; GO:0007264; GO:0008270,COPII vesicle coat; ER to Golgi vesicle-mediated transport; GTP binding; GTPase activity; intracellular protein transport; small GTPase mediated signal transduction; zinc ion binding,PF00071;,,,,,,,,,CPAS1_DICDI,Dictyostelium discoideum (Slime mold),ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264] comp142249_c0_seq2,904,47.5664,0.45551089,0,0,,,,,,,,,2.00E-37,CHOYP_LOC100638372.1.1,,,,,,,,, comp142249_c1_seq2,1755,41.0826,0.41448345,0,0,,9.00E-21,B6JGG2,GTPase Era,GTPase Era,GO:0005525; GO:0006184; GO:0003924; GO:0070181; GO:0005737; GO:0005886; GO:0042274,GTP binding; GTP catabolic process; GTPase activity; SSU rRNA binding; cytoplasm; plasma membrane; ribosomal small subunit biogenesis,PF07650;PF01926;,,,,,,,,,ERA_OLICO,Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5),ribosomal small subunit biogenesis [GO:0042274] comp142249_c3_seq2,1755,41.0826,0.41448345,0,0,,7.00E-47,B0S6U7,"GTPase Era, mitochondrial (ERA-like protein 1)","GTPase Era, mitochondrial (ERA-like protein 1)",GO:0005525; GO:0005743; GO:0005759; GO:0019843; GO:0000028; GO:0043024; GO:0007264,GTP binding; mitochondrial inner membrane; mitochondrial matrix; rRNA binding; ribosomal small subunit assembly; ribosomal small subunit binding; small GTPase mediated signal transduction,PF07650;PF01926;,,,,,,,,,ERAL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ribosomal small subunit assembly [GO:0000028] comp142250_c0_seq1,3067,45.2233,0.47521093,343,2016,,0,A3KMI0,ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29),ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29),GO:0005524; GO:0008026; GO:0016282; GO:0043024; GO:0003743,ATP binding; ATP-dependent helicase activity; eukaryotic 43S preinitiation complex; ribosomal small subunit binding; translation initiation factor activity,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX29_XENLA,Xenopus laevis (African clawed frog), comp142254_c1_seq1,1809,37.2029,0.38445211,446,1736,,4.00E-94,Q9W4V8,Mitochondrial import inner membrane translocase subunit TIM50-C (Tiny tim 50),Mitochondrial import inner membrane translocase subunit TIM50-C (Tiny tim 50),GO:0016021; GO:0005744; GO:0007006; GO:0004722; GO:0015031; GO:0004725,integral to membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial membrane organization; protein serine/threonine phosphatase activity; protein transport; protein tyrosine phosphatase activity,PF03031;,,,,,,,,,TI50C_DROME,Drosophila melanogaster (Fruit fly),mitochondrial membrane organization [GO:0007006]; mitochondrion organization [GO:0007005]; mitotic nuclear division [GO:0007067]; protein dephosphorylation [GO:0006470]; protein import into mitochondrial matrix [GO:0030150]; sensory perception of pain [GO:0019233] comp142255_c0_seq1,3661,40.7266,0.49619345,8,0,,6.00E-110,P06241,Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn),Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn),GO:0005524; GO:0038095; GO:0038096; GO:0031295; GO:0050852; GO:0050798; GO:0007411; GO:0006816; GO:0071375; GO:0005829; GO:0048813; GO:0050966; GO:0005768; GO:0007173; GO:0007631; GO:0008543; GO:0030900; GO:0045087; GO:0007243; GO:0007612; GO:0050900; GO:0046872; GO:0005739; GO:0019048; GO:2001240; GO:0010629; GO:0042177; GO:0001764; GO:0048011; GO:0004715; GO:0005634; GO:0048015; GO:0005886; GO:0030168; GO:0010976; GO:0014069; GO:0046777; GO:0008360; GO:0050690; GO:0042493; GO:0045471; GO:0016032,ATP binding; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell costimulation; T cell receptor signaling pathway; activated T cell proliferation; axon guidance; calcium ion transport; cellular response to peptide hormone stimulus; cytosol; dendrite morphogenesis; detection of mechanical stimulus involved in sensory perception of pain; endosome; epidermal growth factor receptor signaling pathway; feeding behavior; fibroblast growth factor receptor signaling pathway; forebrain development; innate immune response; intracellular protein kinase cascade; learning; leukocyte migration; metal ion binding; mitochondrion; modulation by virus of host morphology or physiology; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of gene expression; negative regulation of protein catabolic process; neuron migration; neurotrophin TRK receptor signaling pathway; non-membrane spanning protein tyrosine kinase activity; nucleus; phosphatidylinositol-mediated signaling; plasma membrane; platelet activation; positive regulation of neuron projection development; postsynaptic density; protein autophosphorylation; regulation of cell shape; regulation of defense response to virus by virus; response to drug; response to ethanol; viral process,PF07714;PF00017;PF00018;,4.00E-123,CHOYP_FYN.1.1,,,,,,,FYN_HUMAN,Homo sapiens (Human),activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of tyrosine phosphorylation of Stat5 protein [GO:0042523]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032] comp142255_c0_seq2,3481,39.6151,0.50083979,25,6,,7.00E-110,P06241,Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn),Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn),GO:0005524; GO:0038095; GO:0038096; GO:0031295; GO:0050852; GO:0050798; GO:0007411; GO:0006816; GO:0071375; GO:0005829; GO:0048813; GO:0050966; GO:0005768; GO:0007173; GO:0007631; GO:0008543; GO:0030900; GO:0045087; GO:0007243; GO:0007612; GO:0050900; GO:0046872; GO:0005739; GO:0019048; GO:2001240; GO:0010629; GO:0042177; GO:0001764; GO:0048011; GO:0004715; GO:0005634; GO:0048015; GO:0005886; GO:0030168; GO:0010976; GO:0014069; GO:0046777; GO:0008360; GO:0050690; GO:0042493; GO:0045471; GO:0016032,ATP binding; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; T cell costimulation; T cell receptor signaling pathway; activated T cell proliferation; axon guidance; calcium ion transport; cellular response to peptide hormone stimulus; cytosol; dendrite morphogenesis; detection of mechanical stimulus involved in sensory perception of pain; endosome; epidermal growth factor receptor signaling pathway; feeding behavior; fibroblast growth factor receptor signaling pathway; forebrain development; innate immune response; intracellular protein kinase cascade; learning; leukocyte migration; metal ion binding; mitochondrion; modulation by virus of host morphology or physiology; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of gene expression; negative regulation of protein catabolic process; neuron migration; neurotrophin TRK receptor signaling pathway; non-membrane spanning protein tyrosine kinase activity; nucleus; phosphatidylinositol-mediated signaling; plasma membrane; platelet activation; positive regulation of neuron projection development; postsynaptic density; protein autophosphorylation; regulation of cell shape; regulation of defense response to virus by virus; response to drug; response to ethanol; viral process,PF07714;PF00017;PF00018;,4.00E-123,CHOYP_FYN.1.1,,,,,,,FYN_HUMAN,Homo sapiens (Human),activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of tyrosine phosphorylation of Stat5 protein [GO:0042523]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032] comp142258_c0_seq1,1836,40.5229,0.50045799,0,0,,3.00E-21,O75382,Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),GO:0005737; GO:0005769; GO:0007399; GO:0008022; GO:0015031; GO:0008270,cytoplasm; early endosome; nervous system development; protein C-terminus binding; protein transport; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM3_HUMAN,Homo sapiens (Human),nervous system development [GO:0007399]; protein transport [GO:0015031] comp142258_c0_seq2,1860,40.5914,0.50680843,2,2,,2.00E-11,Q03601,RING finger protein nhl-1,RING finger protein nhl-1,GO:0008270,zinc ion binding,PF01436;PF00097;,,,,,,,,,NHL1_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567] comp142258_c0_seq6,987,44.5795,0.48726356,16,0,,5.00E-21,O75382,Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),GO:0005737; GO:0005769; GO:0007399; GO:0008022; GO:0015031; GO:0008270,cytoplasm; early endosome; nervous system development; protein C-terminus binding; protein transport; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM3_HUMAN,Homo sapiens (Human),nervous system development [GO:0007399]; protein transport [GO:0015031] comp142259_c1_seq1,3400,43.0294,0.31181871,94,98,,0,A8KBF3,Piwi-like protein 2,Piwi-like protein 2,GO:0043046; GO:0000966; GO:0031047; GO:0030718; GO:0007126; GO:0007275; GO:0005634; GO:0071546; GO:0034584; GO:0034587; GO:0006417,DNA methylation involved in gamete generation; RNA 5'-end processing; gene silencing by RNA; germ-line stem cell maintenance; meiosis; multicellular organismal development; nucleus; pi-body; piRNA binding; piRNA metabolic process; regulation of translation,PF08699;PF02170;PF02171;,0,CHOYP_LOC583253.1.1,,,,,,,PIWL2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gamete generation [GO:0007276]; gene silencing by RNA [GO:0031047]; germ-line stem cell population maintenance [GO:0030718]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; RNA 5'-end processing [GO:0000966] comp142259_c1_seq3,2696,44.6217,0.31388973,0,0,,0,A8KBF3,Piwi-like protein 2,Piwi-like protein 2,GO:0043046; GO:0000966; GO:0031047; GO:0030718; GO:0007126; GO:0007275; GO:0005634; GO:0071546; GO:0034584; GO:0034587; GO:0006417,DNA methylation involved in gamete generation; RNA 5'-end processing; gene silencing by RNA; germ-line stem cell maintenance; meiosis; multicellular organismal development; nucleus; pi-body; piRNA binding; piRNA metabolic process; regulation of translation,PF08699;PF02170;PF02171;,4.00E-140,CHOYP_LOC583253.1.1,,,,,,,PIWL2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gamete generation [GO:0007276]; gene silencing by RNA [GO:0031047]; germ-line stem cell population maintenance [GO:0030718]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; RNA 5'-end processing [GO:0000966] comp142260_c0_seq1,614,41.3681,0.45827245,52,44,,2.00E-08,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp142262_c0_seq3,625,47.36,1.04799375,202,1007,,7.00E-31,Q923B0,Gamma-glutamylaminecyclotransferase (GGACT) (EC 2.3.2.4) (AIG2-like domain-containing protein 1) (Gamma-glutamylamine cyclotransferase),Gamma-glutamylaminecyclotransferase (GGACT) (EC 2.3.2.4) (AIG2-like domain-containing protein 1) (Gamma-glutamylamine cyclotransferase),GO:0042219; GO:0003839,cellular modified amino acid catabolic process; gamma-glutamylcyclotransferase activity,PF06094;,,,,,,,,,A2LD1_MOUSE,Mus musculus (Mouse),cellular modified amino acid catabolic process [GO:0042219] comp142264_c0_seq3,4896,35.2941,0.43952408,203,367,,3.00E-47,Q8BQZ5,Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K),Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K),GO:0003723; GO:0005847; GO:0006397; GO:0005739; GO:0008270,RNA binding; mRNA cleavage and polyadenylation specificity factor complex; mRNA processing; mitochondrion; zinc ion binding,PF00642;PF00098;,,,,,,,,,CPSF4_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397] comp142264_c0_seq6,1222,39.9345,0.37251908,2,0,,7.00E-104,O95639,Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog),Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog),GO:0003723; GO:0005847; GO:0006397; GO:0005739; GO:0046778; GO:0019058; GO:0008270,RNA binding; mRNA cleavage and polyadenylation specificity factor complex; mRNA processing; mitochondrion; modification by virus of host mRNA processing; viral life cycle; zinc ion binding,PF00642;PF00098;,3.00E-93,CHOYP_ISCW_ISCW021476.1.1,,,,,,,CPSF4_HUMAN,Homo sapiens (Human),"modification by virus of host mRNA processing [GO:0046778]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp142265_c0_seq4,504,44.6429,0.28890274,3,58,,2.00E-65,Q9HC38,Glyoxalase domain-containing protein 4,Glyoxalase domain-containing protein 4,GO:0005739,mitochondrion,,8.00E-52,CHOYP_BRAFLDRAFT_116041.1.1,6.00E-58,ruditapes_c31317,,,,,GLOD4_HUMAN,Homo sapiens (Human), comp142265_c0_seq5,544,42.4632,0.57248093,35,285,,1.00E-68,Q5I0D1,Glyoxalase domain-containing protein 4,Glyoxalase domain-containing protein 4,GO:0005739,mitochondrion,,,,,,,,,,GLOD4_RAT,Rattus norvegicus (Rat), comp142266_c0_seq1,2502,46.6827,1.02338479,2965,11,male>female,5.00E-25,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,2.00E-46,ruditapes_c10266,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp142267_c0_seq1,1343,28.0715,0.41890537,157,244,,1.00E-20,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp142269_c0_seq1,3075,37.8862,0.35563227,16,172,,0,Q6P4Y0,Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.-.-.-) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase),Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase),GO:0051539; GO:0009451; GO:0005789; GO:0016021; GO:0046872; GO:0008033; GO:0016740,"4 iron, 4 sulfur cluster binding; RNA modification; endoplasmic reticulum membrane; integral to membrane; metal ion binding; tRNA processing; transferase activity",PF04055;PF01938;PF00919;,0,CHOYP_CDKAL.1.1,,,,,,,CDKAL_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142269_c0_seq3,3133,37.5997,0.36337815,19,111,,0,Q6P4Y0,Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.-.-.-) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase),Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase),GO:0051539; GO:0009451; GO:0005789; GO:0016021; GO:0046872; GO:0008033; GO:0016740,"4 iron, 4 sulfur cluster binding; RNA modification; endoplasmic reticulum membrane; integral to membrane; metal ion binding; tRNA processing; transferase activity",PF04055;PF01938;PF00919;,0,CHOYP_CDKAL.1.1,,,,,,,CDKAL_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142270_c3_seq1,860,41.2791,0.44573929,21,43,,3.00E-45,Q9BQS8,FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7),FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7),GO:0005776; GO:0031410; GO:0016021; GO:0005770; GO:0005764; GO:0046872; GO:0072383,autophagic vacuole; cytoplasmic vesicle; integral to membrane; late endosome; lysosome; metal ion binding; plus-end-directed vesicle transport along microtubule,PF01363;PF02759;,5.00E-45,CHOYP_LOC100372298.1.1,,,,,,,FYCO1_HUMAN,Homo sapiens (Human),plus-end-directed vesicle transport along microtubule [GO:0072383] comp142270_c4_seq3,5399,34.8768,0.21696435,148,191,,2.00E-26,Q9BQS8,FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7),FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7),GO:0005776; GO:0031410; GO:0016021; GO:0005770; GO:0005764; GO:0046872; GO:0072383,autophagic vacuole; cytoplasmic vesicle; integral to membrane; late endosome; lysosome; metal ion binding; plus-end-directed vesicle transport along microtubule,PF01363;PF02759;,6.00E-28,CHOYP_LOC100372298.1.1,,,,,,,FYCO1_HUMAN,Homo sapiens (Human),plus-end-directed vesicle transport along microtubule [GO:0072383] comp142271_c0_seq1,2048,40.0391,1.08592841,1328,15,,2.00E-27,O95863,Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna),Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna),GO:0061314; GO:0001078; GO:0060536; GO:0016477; GO:0005737; GO:0001837; GO:0031069; GO:0060972; GO:0001707; GO:0046872; GO:0043518; GO:0060806; GO:1902230; GO:0010957; GO:0005634; GO:0001649; GO:0060021; GO:0030335; GO:0010718; GO:0045893; GO:2000810; GO:0043565; GO:0060707,"Notch signaling involved in heart development; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; cartilage morphogenesis; cell migration; cytoplasm; epithelial to mesenchymal transition; hair follicle morphogenesis; left/right pattern formation; mesoderm formation; metal ion binding; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of cell differentiation involved in embryonic placenta development; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of vitamin D biosynthetic process; nucleus; osteoblast differentiation; palate development; positive regulation of cell migration; positive regulation of epithelial to mesenchymal transition; positive regulation of transcription, DNA-dependent; regulation of tight junction assembly; sequence-specific DNA binding; trophoblast giant cell differentiation",PF00096;PF13912;,,,,,,,,,SNAI1_HUMAN,Homo sapiens (Human),"cartilage morphogenesis [GO:0060536]; cell migration [GO:0016477]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; hair follicle morphogenesis [GO:0031069]; left/right pattern formation [GO:0060972]; mesoderm formation [GO:0001707]; negative regulation of cell differentiation involved in embryonic placenta development [GO:0060806]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; Notch signaling involved in heart development [GO:0061314]; osteoblast differentiation [GO:0001649]; palate development [GO:0060021]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of bicellular tight junction assembly [GO:2000810]; trophoblast giant cell differentiation [GO:0060707]" comp142272_c1_seq1,2872,43.1407,0.54678162,64,66,,2.00E-123,Q68SB1,Double-stranded RNA-binding protein Staufen homolog 2 (r-staufen protein),Double-stranded RNA-binding protein Staufen homolog 2 (r-staufen protein),GO:0003723; GO:0005783; GO:0005874; GO:0005730; GO:0006810,RNA binding; endoplasmic reticulum; microtubule; nucleolus; transport,PF00035;PF16482;,3.00E-104,CHOYP_LOC100533450.1.1,,,,,,,STAU2_RAT,Rattus norvegicus (Rat),cellular response to oxidative stress [GO:0034599]; eye morphogenesis [GO:0048592]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of filopodium assembly [GO:0051489]; regulation of gene expression [GO:0010468]; transport [GO:0006810] comp142272_c1_seq2,2802,43.2191,0.53561881,19,98,,2.00E-127,Q7ZW47,Double-stranded RNA-binding protein Staufen homolog 2,Double-stranded RNA-binding protein Staufen homolog 2,GO:0003723; GO:0005874; GO:0006810,RNA binding; microtubule; transport,PF00035;PF16482;,3.00E-104,CHOYP_LOC100533450.1.1,,,,,,,STAU2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),germ cell development [GO:0007281]; germ cell migration [GO:0008354]; transport [GO:0006810] comp142273_c0_seq2,1906,45.0682,0.87503848,146,408,,3.00E-55,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp142274_c1_seq1,1939,31.0985,0.455216,1152,4079,,,,,,,,,,,3.00E-36,ruditapes_c10444,,,,,,, comp142275_c0_seq1,1009,32.9039,0.45572521,31,95,,7.00E-06,B2RXH4,BTB/POZ domain-containing protein 18,BTB/POZ domain-containing protein 18,,,PF00651;,,,,,,,,,BTBDI_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp142275_c1_seq2,2790,37.9928,0.30864646,152,347,,2.00E-16,Q6ZR52,Zinc finger protein 493,Zinc finger protein 493,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN493_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142278_c0_seq3,2088,36.6858,0.40878064,262,1229,,5.00E-78,Q7ZWE9,UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK),UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK),GO:0005524; GO:0004127; GO:0005737; GO:0004550; GO:0009142; GO:0005634; GO:0006221,ATP binding; cytidylate kinase activity; cytoplasm; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; nucleus; pyrimidine nucleotide biosynthetic process,,2.00E-66,CHOYP_KCY.1.1,,,,,,,KCY_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine nucleotide biosynthetic process [GO:0006221] comp142283_c0_seq2,3577,38.3841,0.50541999,486,454,,0,B5DF89,Cullin-3,Cullin-3,GO:0048208; GO:0031463; GO:0005794; GO:0031208; GO:0016055; GO:0016477; GO:0008054; GO:0000910; GO:0040016; GO:0007369; GO:0007229; GO:0035024; GO:0005634; GO:0005827; GO:0032467; GO:0043161; GO:0006513; GO:0000209; GO:0017145; GO:0043149; GO:0001831; GO:0004842,COPII vesicle coating; Cul3-RING ubiquitin ligase complex; Golgi apparatus; POZ domain binding; Wnt receptor signaling pathway; cell migration; cyclin catabolic process; cytokinesis; embryonic cleavage; gastrulation; integrin-mediated signaling pathway; negative regulation of Rho protein signal transduction; nucleus; polar microtubule; positive regulation of cytokinesis; proteasomal ubiquitin-dependent protein catabolic process; protein monoubiquitination; protein polyubiquitination; stem cell division; stress fiber assembly; trophectodermal cellular morphogenesis; ubiquitin-protein ligase activity,PF00888;PF10557;,0,CHOYP_CUL3B.1.1,,,,,,,CUL3_RAT,Rattus norvegicus (Rat),cell projection organization [GO:0030030]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; ER to Golgi vesicle-mediated transport [GO:0006888]; integrin-mediated signaling pathway [GO:0007229]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; stem cell division [GO:0017145] comp142285_c0_seq1,4234,43.2924,0.33109179,0,0,,,,,,,,,8.00E-133,CHOYP_CCAR1.1.1,,,,,,,,, comp142285_c0_seq11,3977,41.2874,0.35387993,0,0,,1.00E-43,Q5R8S0,Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2),Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2),GO:0044609; GO:0000993; GO:0008380; GO:0006915; GO:0004857; GO:0006397; GO:1902230; GO:0000790; GO:2000003; GO:0043065; GO:0032784; GO:0009411,"DBIRD complex; RNA polymerase II core binding; RNA splicing; apoptotic process; enzyme inhibitor activity; mRNA processing; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; nuclear chromatin; positive regulation of DNA damage checkpoint; positive regulation of apoptotic process; regulation of DNA-dependent transcription, elongation; response to UV",PF14443;PF14444;,1.00E-27,CHOYP_LOC100372630.1.1,,,,,,,K1967_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; mRNA processing [GO:0006397]; negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA damage checkpoint [GO:2000003]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp142285_c0_seq12,2310,36.6234,0.35404484,0,0,,,,,,,,,4.00E-133,CHOYP_CCAR1.1.1,,,,,,,,, comp142285_c0_seq13,2502,37.7298,0.38967681,0,0,,,,,,,,,5.00E-133,CHOYP_CCAR1.1.1,,,,,,,,, comp142285_c0_seq14,4462,43.4783,0.34017829,0,0,,7.00E-148,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,2.00E-27,CHOYP_LOC100372630.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq17,4441,43.3686,0.34356836,0,0,,6.00E-148,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,0,CHOYP_CCAR1.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq18,4998,42.6971,0.35525709,0,0,,1.00E-43,Q5R8S0,Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2),Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2),GO:0044609; GO:0000993; GO:0008380; GO:0006915; GO:0004857; GO:0006397; GO:1902230; GO:0000790; GO:2000003; GO:0043065; GO:0032784; GO:0009411,"DBIRD complex; RNA polymerase II core binding; RNA splicing; apoptotic process; enzyme inhibitor activity; mRNA processing; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; nuclear chromatin; positive regulation of DNA damage checkpoint; positive regulation of apoptotic process; regulation of DNA-dependent transcription, elongation; response to UV",PF14443;PF14444;,2.00E-27,CHOYP_LOC100372630.1.1,,,,,,,K1967_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; mRNA processing [GO:0006397]; negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA damage checkpoint [GO:2000003]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp142285_c0_seq19,3769,40.9923,0.34070876,0,0,,5.00E-71,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,7.00E-133,CHOYP_CCAR1.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq2,5019,42.7774,0.35235922,0,0,,1.00E-146,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,2.00E-27,CHOYP_LOC100372630.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq23,4783,42.5465,0.34602424,2,64,,,,,,,,,9.00E-133,CHOYP_CCAR1.1.1,,,,,,,,, comp142285_c0_seq25,5008,42.8115,0.35254787,0,0,,1.00E-146,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,2.00E-27,CHOYP_LOC100372630.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq3,4194,43.2046,0.33572935,0,0,,,,,,,,,8.00E-133,CHOYP_CCAR1.1.1,,,,,,,,, comp142285_c0_seq5,4443,43.4391,0.34214272,0,0,,6.00E-148,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,,,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq6,4987,42.7311,0.35544979,0,0,,1.00E-146,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,2.00E-27,CHOYP_LOC100372630.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142285_c0_seq8,3577,40.4529,0.31976844,0,0,,,,,,,,,6.00E-133,CHOYP_CCAR1.1.1,,,,,,,,, comp142285_c0_seq9,3785,40.7398,0.33629421,0,0,,6.00E-150,Q8CH18,Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1),GO:0006915; GO:0007049; GO:0030374; GO:0003676; GO:0048471; GO:0006355; GO:0006351,"apoptotic process; cell cycle; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14443;PF14444;PF02037;,0,CHOYP_CCAR1.1.1,,,,,,,CCAR1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142288_c1_seq1,2026,43.2379,0.36196437,318,2350,,3.00E-172,Q96SY0,von Willebrand factor A domain-containing protein 9,von Willebrand factor A domain-containing protein 9,,,PF13519;,3.00E-77,CHOYP_VWA9.1.1,,,,,,,CO044_HUMAN,Homo sapiens (Human),snRNA transcription from RNA polymerase II promoter [GO:0042795] comp142289_c0_seq1,4392,44.877,0.54744537,0,0,,,,,,,,,0,CHOYP_PDS5B.1.1,,,,,,,,, comp142289_c0_seq2,5935,42.8138,0.52670482,341,123,,0,Q5F3U9,Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor),Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor),GO:0051301; GO:0007064; GO:0008285; GO:0005634,cell division; mitotic sister chromatid cohesion; negative regulation of cell proliferation; nucleus,,0,CHOYP_PDS5B.1.1,,,,,,,PDS5B_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of cell proliferation [GO:0008285] comp142291_c2_seq2,8873,38.6002,0.48135301,172,822,,4.00E-21,Q91VX2,Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1),Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1),,,PF12478;,4.00E-14,CHOYP_BRAFLDRAFT_125234.2.2,,,,,,,UBAP2_MOUSE,Mus musculus (Mouse), comp142291_c2_seq3,8908,38.5833,0.47691427,220,1046,,4.00E-21,Q91VX2,Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1),Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1),,,PF12478;,4.00E-14,CHOYP_BRAFLDRAFT_125234.2.2,1.00E-17,ruditapes_c8858,,,,,UBAP2_MOUSE,Mus musculus (Mouse), comp142295_c0_seq1,1068,35.7678,0.99673747,163,1411,,,,,,,,,2.00E-13,CHOYP_TBB.4.7,2.00E-17,ruditapes_lrc15708,,,,,,, comp142296_c1_seq1,587,38.3305,0.57478173,38,99,,2.00E-66,B0BN49,"RNA-binding motif protein, X-linked 2","RNA-binding motif protein, X-linked 2",GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,1.00E-62,CHOYP_BM1_02690.1.1,,,,,,,RBMX2_RAT,Rattus norvegicus (Rat),"mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]" comp142301_c1_seq2,3000,44.2667,0.52540552,2037,210,,1.00E-99,Q9UPU9,Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A),Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A),GO:0030054; GO:0005737; GO:0030425; GO:0045727; GO:0045202; GO:0030371,cell junction; cytoplasm; dendrite; positive regulation of translation; synapse; translation repressor activity,PF00536;,8.00E-36,CHOYP_SMAG1.1.1,,,,,,,SMAG1_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of translation [GO:0045727]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]" comp142305_c0_seq1,4835,44.5915,0.53479863,6,0,,0,Q9TU34,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0005789; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0035091; GO:0051209; GO:0030658,"endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; phosphatidylinositol binding; release of sequestered calcium ion into cytosol; transport vesicle membrane",PF08709;PF00520;PF02815;PF08454;PF01365;,0,CHOYP_LOC100533406.2.2,,,,,,,ITPR1_BOVIN,Bos taurus (Bovine),intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209] comp142305_c0_seq4,4781,44.4886,0.51815762,4,22,,1.00E-15,Q9NA13,"Inositol 1,4,5-trisphosphate receptor-like protein A","Inositol 1,4,5-trisphosphate receptor-like protein A",GO:0048102; GO:0030244; GO:0034670; GO:0005783; GO:0005789; GO:0005220; GO:0016021; GO:0051209,"autophagic cell death; cellulose biosynthetic process; chemotaxis to arachidonic acid; endoplasmic reticulum; endoplasmic reticulum membrane; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; release of sequestered calcium ion into cytosol",PF08454;PF01365;,0,CHOYP_LOC100533406.2.2,,,,,,,IPLA_DICDI,Dictyostelium discoideum (Slime mold),aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209] comp142308_c0_seq1,1375,35.2727,0.46797971,452,2109,,3.00E-08,A6NEY8,Putative prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1) (Prolyl-tRNA synthetase associated domain-containing protein 1 pseudogene),Putative prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1) (Prolyl-tRNA synthetase associated domain-containing protein 1 pseudogene),GO:0002161; GO:0006450,aminoacyl-tRNA editing activity; regulation of translational fidelity,PF04073;,,,6.00E-38,ruditapes2_c3200,,,,,PRXD1_HUMAN,Homo sapiens (Human), comp142309_c1_seq1,1612,33.995,0.52322725,114,350,,6.00E-75,Q8CCA0,DCN1-like protein 4 (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4),DCN1-like protein 4 (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4),,,PF03556;,2.00E-85,CHOYP_DCNL4.1.2,,,,,,,DCNL4_MOUSE,Mus musculus (Mouse),positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] comp142309_c1_seq3,1599,34.0213,0.526316,87,81,,3.00E-06,Q12395,Defective in cullin neddylation protein 1,Defective in cullin neddylation protein 1,GO:0019788; GO:0051443; GO:0045116; GO:0043130,NEDD8 ligase activity; positive regulation of ubiquitin-protein ligase activity; protein neddylation; ubiquitin binding,PF03556;,8.00E-52,CHOYP_DCNL4.2.2,,,,,,,DCN1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] comp142310_c0_seq2,953,43.6516,0.46738573,5,38,,,,,,,,,3.00E-29,CHOYP_NEMVEDRAFT_V1G241686.1.1,,,,,,,,, comp142310_c0_seq4,869,44.3038,0.30805728,9,23,,,,,,,,,1.00E-27,CHOYP_NEMVEDRAFT_V1G241686.1.1,,,,,,,,, comp142311_c0_seq1,1616,37.7475,0.78221779,2576,1325,,7.00E-31,Q8TBZ9,Uncharacterized protein C7orf62,Uncharacterized protein C7orf62,,,,1.00E-18,CHOYP_LOC579291.1.1,2.00E-13,ruditapes_c12893,,,,,CG062_HUMAN,Homo sapiens (Human), comp142312_c1_seq1,2216,34.6119,0.50225183,289,336,,2.00E-40,Q39752,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALM_FAGSY,Fagus sylvatica (Beechnut), comp142312_c1_seq2,2202,34.5141,0.50881526,127,240,,4.00E-91,Q9R1K9,Centrin-2 (Caltractin isoform 1),Centrin-2 (Caltractin isoform 1),GO:0005524; GO:0008026; GO:0031683; GO:0071942; GO:0005509; GO:0051301; GO:0005814; GO:0007099; GO:0032795; GO:0005932; GO:0008017; GO:0007067; GO:0003676; GO:0006289; GO:0032391; GO:0032465; GO:0007283,ATP binding; ATP-dependent helicase activity; G-protein beta/gamma-subunit complex binding; XPC complex; calcium ion binding; cell division; centriole; centriole replication; heterotrimeric G-protein binding; microtubule basal body; microtubule binding; mitosis; nucleic acid binding; nucleotide-excision repair; photoreceptor connecting cilium; regulation of cytokinesis; spermatogenesis,PF13499;,2.00E-98,CHOYP_CETN1.1.3,3.00E-12,ruditapes_c27296,,,,,CETN2_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; centriole replication [GO:0007099]; mitotic nuclear division [GO:0007067]; nucleotide-excision repair [GO:0006289]; regulation of cytokinesis [GO:0032465]; spermatogenesis [GO:0007283] comp142313_c0_seq2,2194,38.7876,0.52241667,0,0,,1.00E-101,Q5R5X8,Adenylyl cyclase-associated protein 2 (CAP 2),Adenylyl cyclase-associated protein 2 (CAP 2),GO:0000902; GO:0007010; GO:0005886,cell morphogenesis; cytoskeleton organization; plasma membrane,PF08603;PF01213;,5.00E-43,CHOYP_CAP1.1.1,2.00E-84,ruditapes2_c1616,,,,,CAP2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010] comp142318_c0_seq2,2491,43.5167,0.4873534,242,402,,0,Q04446,"1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)","1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)",GO:0003844; GO:0043169; GO:0005829; GO:0006006; GO:0005978; GO:0004553; GO:0044281,"1,4-alpha-glucan branching enzyme activity; cation binding; cytosol; glucose metabolic process; glycogen biosynthetic process; hydrolase activity, hydrolyzing O-glycosyl compounds; small molecule metabolic process",PF00128;PF02806;PF02922;,0,CHOYP_LOC100376863.1.1,,,,,,,GLGB_HUMAN,Homo sapiens (Human),generation of precursor metabolites and energy [GO:0006091]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977] comp142319_c0_seq1,2506,40.0239,0.47996309,1033,2925,,2.00E-85,Q9NPI1,Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1),Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1),GO:0016055; GO:0007049; GO:0005737; GO:0070577; GO:2000134; GO:0008285; GO:0045892; GO:0005634; GO:0035066; GO:0045893; GO:0006357; GO:0003713; GO:0003714; GO:0008134; GO:0044212; GO:0006351,"Wnt receptor signaling pathway; cell cycle; cytoplasm; histone acetyl-lysine binding; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of histone acetylation; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription corepressor activity; transcription factor binding; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00439;PF12024;,1.00E-83,CHOYP_LOC100116878.1.1,,,,,,,BRD7_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp142320_c0_seq1,6178,48.5918,0.69670076,2772,10625,,1.00E-11,P08120,Collagen alpha-1(IV) chain,Collagen alpha-1(IV) chain,GO:0005587; GO:0007391; GO:0005201; GO:0035848,collagen type IV; dorsal closure; extracellular matrix structural constituent; oviduct morphogenesis,PF01413;PF01391;,3.00E-25,CHOYP_contig_027593,,,,,,,CO4A1_DROME,Drosophila melanogaster (Fruit fly),cardiac muscle cell development [GO:0055013]; dorsal closure [GO:0007391]; intestinal epithelial structure maintenance [GO:0060729]; oviduct morphogenesis [GO:0035848]; post-embryonic digestive tract morphogenesis [GO:0048621] comp142321_c0_seq1,877,40.1368,0.7369586,100,943,,7.00E-46,C3ZAH2,"1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD)","1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD)",GO:0019509; GO:0010309; GO:0005737; GO:0005506; GO:0005634,L-methionine salvage from methylthioadenosine; acireductone dioxygenase [iron(II)-requiring] activity; cytoplasm; iron ion binding; nucleus,PF03079;,4.00E-33,CHOYP_MTND.2.3,,,,,,,MTND_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; methionine metabolic process [GO:0006555] comp142321_c0_seq2,1881,35.3535,0.5169195,322,560,,6.00E-73,Q91WN1,DnaJ homolog subfamily C member 9,DnaJ homolog subfamily C member 9,GO:0035176,social behavior,PF00226;,6.00E-35,CHOYP_DNJC9.1.1,,,,,,,DNJC9_MOUSE,Mus musculus (Mouse),positive regulation of ATPase activity [GO:0032781]; social behavior [GO:0035176] comp142323_c0_seq1,1750,37.7143,1.14198487,0,0,,1.00E-41,Q5UE96,Potassium channel subfamily K member 1,Potassium channel subfamily K member 1,GO:0005768; GO:0016021; GO:0005267; GO:0005244,endosome; integral to membrane; potassium channel activity; voltage-gated ion channel activity,PF07885;,2.00E-60,CHOYP_LOC100162572.1.1,,,,,,,KCNK1_RABIT,Oryctolagus cuniculus (Rabbit),potassium ion transmembrane transport [GO:0071805]; regulation of resting membrane potential [GO:0060075]; sodium ion transmembrane transport [GO:0035725] comp142323_c0_seq2,1746,37.5716,1.13695776,12,28,,3.00E-22,O17185,Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38),Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38),GO:0005887; GO:0036195; GO:0005267; GO:0006937; GO:0055120,integral to plasma membrane; muscle cell projection membrane; potassium channel activity; regulation of muscle contraction; striated muscle dense body,PF07885;,,,,,,,,,SUP9_CAEEL,Caenorhabditis elegans,potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322] comp142323_c0_seq4,1633,36.9871,1.16458377,0,0,,2.00E-13,Q63ZI0,Potassium channel subfamily K member 9,Potassium channel subfamily K member 9,GO:0016021; GO:0005267; GO:0005244,integral to membrane; potassium channel activity; voltage-gated ion channel activity,PF07885;,,,,,,,,,KCNK9_XENLA,Xenopus laevis (African clawed frog), comp142323_c0_seq5,1637,37.2022,1.16611339,0,0,,2.00E-12,P97438,Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two pore potassium channel TPKC1),Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two pore potassium channel TPKC1),GO:0007186; GO:0030322; GO:0005249; GO:0008076,G-protein coupled receptor signaling pathway; stabilization of membrane potential; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF07885;,2.00E-34,CHOYP_LOC100162572.1.1,,,,,,,KCNK2_MOUSE,Mus musculus (Mouse),cardiac ventricle development [GO:0003231]; cellular response to hypoxia [GO:0071456]; cochlea development [GO:0090102]; G-protein coupled receptor signaling pathway [GO:0007186]; memory [GO:0007613]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of DNA biosynthetic process [GO:2000279]; positive regulation of cell death [GO:0010942]; positive regulation of cellular response to hypoxia [GO:1900039]; potassium ion transport [GO:0006813]; regulation of membrane potential [GO:0042391]; response to axon injury [GO:0048678]; response to mechanical stimulus [GO:0009612]; stabilization of membrane potential [GO:0030322] comp142324_c0_seq1,3646,46.2699,0.52012752,0,0,,0,Q8VBX6,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0007155; GO:0031410; GO:0030425; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; cell adhesion; cytoplasmic vesicle; dendrite; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,,,,,,,,,MPDZ_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; myelination [GO:0042552] comp142324_c0_seq10,2875,45.913,0.53826449,0,0,,0,O75970,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0016327; GO:0007155; GO:0005737; GO:0031410; GO:0030425; GO:0019048; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; apicolateral plasma membrane; cell adhesion; cytoplasm; cytoplasmic vesicle; dendrite; modulation by virus of host morphology or physiology; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,3.00E-168,CHOYP_MPDZ.3.3,,,,,,,MPDZ_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032] comp142324_c0_seq2,2765,46.2568,0.53011949,0,0,,,,,,,,,1.00E-121,CHOYP_LOC100165785.1.1,,,,,,,,, comp142324_c0_seq3,2747,46.0138,0.54043349,0,0,,0,O75970,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0016327; GO:0007155; GO:0005737; GO:0031410; GO:0030425; GO:0019048; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; apicolateral plasma membrane; cell adhesion; cytoplasm; cytoplasmic vesicle; dendrite; modulation by virus of host morphology or physiology; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,3.00E-168,CHOYP_MPDZ.3.3,,,,,,,MPDZ_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032] comp142324_c0_seq4,3625,46.3172,0.51701181,0,0,,7.00E-13,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,,,,,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp142324_c0_seq5,744,41.9355,0.5217956,0,2,,1.00E-15,Q2KIB6,Protein lin-7 homolog B (Lin-7B),Protein lin-7 homolog B (Lin-7B),GO:0016323; GO:0006887; GO:0043005; GO:0007269; GO:0014069; GO:0045211; GO:0015031; GO:0005923,basolateral plasma membrane; exocytosis; neuron projection; neurotransmitter secretion; postsynaptic density; postsynaptic membrane; protein transport; tight junction,PF02828;PF00595;,2.00E-24,CHOYP_MPDZ.1.3,,,,,,,LIN7B_BOVIN,Bos taurus (Bovine),exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031] comp142324_c0_seq6,2744,46.3192,0.53289039,4,7,,4.00E-13,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,,,,,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp142324_c0_seq7,1994,45.7372,0.57023486,0,0,,,,,,,,,9.00E-122,CHOYP_LOC100165785.1.1,,,,,,,,, comp142324_c0_seq8,1866,45.8735,0.57552738,0,0,,2.00E-73,Q63ZW7,InaD-like protein (Inadl protein) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions),InaD-like protein (Inadl protein) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions),GO:0045177; GO:0016324; GO:0048471; GO:0005923,apical part of cell; apical plasma membrane; perinuclear region of cytoplasm; tight junction,PF09045;PF00595;,6.00E-124,CHOYP_MPDZ.3.3,,,,,,,INADL_MOUSE,Mus musculus (Mouse), comp142324_c0_seq9,1134,43.1217,0.45706267,6,0,,2.00E-18,Q4L1J4,"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)","Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)",GO:0005524; GO:0005737; GO:0016020; GO:0005923,ATP binding; cytoplasm; membrane; tight junction,PF00625;PF00595;PF00397;,1.00E-34,CHOYP_MPDZ.1.3,,,,,,,MAGI1_RAT,Rattus norvegicus (Rat), comp142324_c1_seq11,1335,41.2734,0.58142144,107,282,,1.00E-140,Q68ED3,PAP-associated domain-containing protein 5 (EC 2.7.7.-) (Topoisomerase-related function protein 4-2) (TRF4-2),Non-canonical poly(A) RNA polymerase PAPD5 (EC 2.7.7.19) (PAP-associated domain-containing protein 5) (Terminal uridylyltransferase 3) (TUTase 3) (Topoisomerase-related function protein 4-2) (TRF4-2),GO:0003677; GO:0006260; GO:0003887; GO:0051301; GO:0005737; GO:0071044; GO:0046872; GO:0007067; GO:0005634,DNA binding; DNA replication; DNA-directed DNA polymerase activity; cell division; cytoplasm; histone mRNA catabolic process; metal ion binding; mitosis; nucleus,PF01909;PF03828;,8.00E-133,CHOYP_LOC552662.1.1,,,,,,,PAPD5_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; histone mRNA catabolic process [GO:0071044]; mitotic nuclear division [GO:0007067]; mRNA processing [GO:0006397]; rRNA processing [GO:0006364] comp142325_c0_seq1,2168,28.7823,0.33574819,374,1881,,,,,,,,,,,9.00E-25,ruditapes_c29246,,,,,,, comp142327_c0_seq1,1978,42.366,0.62658324,2081,19669,,0,Q6TH15,Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7),Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; regulation of translational initiation; translation initiation factor activity; translational initiation,PF05091;,0,CHOYP_SC31A.2.2,1.00E-169,ruditapes2_c168,,,,,EIF3D_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp142328_c1_seq1,4043,44.5956,0.41935192,9,3,,0,Q8IWV7,E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin-1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I),E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin-1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I),GO:0071233; GO:0005829; GO:0070728; GO:0032007; GO:0000502; GO:0000151; GO:0006511; GO:0004842; GO:0008270,cellular response to leucine; cytosol; leucine binding; negative regulation of TOR signaling cascade; proteasome complex; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02617;PF02207;,2.00E-50,CHOYP_UBR2.2.2,,,,,,,UBR1_HUMAN,Homo sapiens (Human),cellular response to leucine [GO:0071233]; negative regulation of TOR signaling [GO:0032007]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp142328_c1_seq2,2420,44.0909,0.42056291,7,4,,9.00E-163,Q6WKZ8,E3 ubiquitin-protein ligase UBR2 (EC 6.3.2.-) (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II),E3 ubiquitin-protein ligase UBR2 (EC 6.3.2.-) (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II),GO:0071233; GO:0006342; GO:0033522; GO:0070728; GO:0007141; GO:0032007; GO:0005634; GO:0005886; GO:0007283; GO:0000151; GO:0006511; GO:0004842; GO:0008270,cellular response to leucine; chromatin silencing; histone H2A ubiquitination; leucine binding; male meiosis I; negative regulation of TOR signaling cascade; nucleus; plasma membrane; spermatogenesis; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02617;PF02207;,,,,,,,,,UBR2_MOUSE,Mus musculus (Mouse),cellular response to leucine [GO:0071233]; chromatin silencing [GO:0006342]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; negative regulation of TOR signaling [GO:0032007]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp142328_c1_seq4,2773,44.8972,0.41542392,0,0,,2.00E-147,Q8IWV7,E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin-1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I),E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin-1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I),GO:0071233; GO:0005829; GO:0070728; GO:0032007; GO:0000502; GO:0000151; GO:0006511; GO:0004842; GO:0008270,cellular response to leucine; cytosol; leucine binding; negative regulation of TOR signaling cascade; proteasome complex; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02617;PF02207;,2.00E-50,CHOYP_UBR2.2.2,,,,,,,UBR1_HUMAN,Homo sapiens (Human),cellular response to leucine [GO:0071233]; negative regulation of TOR signaling [GO:0032007]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp142329_c0_seq2,2221,31.8775,0.66112353,224,195,,4.00E-32,Q4KLZ1,Transmembrane protein 186,Transmembrane protein 186,GO:0016021,integral to membrane,,,,,,,,,,TM186_RAT,Rattus norvegicus (Rat), comp142330_c1_seq1,2801,34.9875,0.56411619,250,693,,2.00E-147,Q28BP9,FAS-associated factor 2 (UBX domain-containing protein 8),FAS-associated factor 2 (UBX domain-containing protein 8),GO:0005783; GO:0005811,endoplasmic reticulum; lipid particle,PF00789;,4.00E-102,CHOYP_FAF2A.1.1,,,,,,,FAF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142330_c1_seq2,1452,33.0579,0.59676814,80,212,,,,,,,,,8.00E-26,CHOYP_FAF2.1.1,,,,,,,,, comp142330_c2_seq1,551,43.0127,0.55318722,2,0,,6.00E-39,P78312,Protein FAM193A (Protein IT14),Protein FAM193A (Protein IT14),GO:0005737; GO:0005886,cytoplasm; plasma membrane,PF15914;,,,,,,,,,F193A_HUMAN,Homo sapiens (Human), comp142330_c2_seq2,571,46.0595,0.62871881,86,107,,1.00E-09,Q96PV7,Protein FAM193B,Protein FAM193B,,,PF15914;,,,,,,,,,F193B_HUMAN,Homo sapiens (Human), comp142330_c2_seq5,1358,44.6981,0.66487316,28,30,,,,,,,,,2.00E-52,CHOYP_FAM193A.1.1,,,,,,,,, comp142330_c2_seq6,623,44.4623,0.29277523,79,93,,,,,,,,,5.00E-11,CHOYP_LOC100370477.1.2,,,,,,,,, comp142332_c0_seq3,2500,40.2,0.48568119,0,0,,8.00E-06,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,6.00E-18,CHOYP_ISCW_ISCW019933.1.1,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp142332_c0_seq4,2480,40.4032,0.48466312,0,0,,4.00E-07,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,5.00E-18,CHOYP_ISCW_ISCW019933.1.1,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142333_c0_seq1,3572,38.9978,0.37795129,0,0,,8.00E-180,P27824,Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90),Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90),GO:0007568; GO:0019886; GO:0002474; GO:0030424; GO:0005509; GO:0072583; GO:0032839; GO:0043197; GO:0005788; GO:0071556; GO:0042470; GO:0043025; GO:0043687; GO:0018279; GO:0006457; GO:0009306; GO:0005840; GO:0048488; GO:0051082,aging; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; axon; calcium ion binding; clathrin-mediated endocytosis; dendrite cytoplasm; dendritic spine; endoplasmic reticulum lumen; integral to lumenal side of endoplasmic reticulum membrane; melanosome; neuronal cell body; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding; protein secretion; ribosome; synaptic vesicle endocytosis; unfolded protein binding,PF00262;,1.00E-41,CHOYP_LOC100304606.1.1,,,,,,,CALX_HUMAN,Homo sapiens (Human),aging [GO:0007568]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; chaperone-mediated protein folding [GO:0061077]; clathrin-mediated endocytosis [GO:0072583]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; synaptic vesicle endocytosis [GO:0048488] comp142333_c0_seq2,4393,37.2638,0.35518607,0,0,,3.00E-51,Q2HWU3,Calreticulin,Calreticulin,GO:0005509; GO:0006457; GO:0050821; GO:0033018,calcium ion binding; protein folding; protein stabilization; sarcoplasmic reticulum lumen,PF00262;,,,,,,,,,CALR_MACFU,Macaca fuscata fuscata (Japanese macaque),protein folding [GO:0006457]; protein stabilization [GO:0050821] comp142333_c0_seq3,4422,37.3134,0.35863026,0,0,,7.00E-167,Q3SYT6,Calmegin,Calmegin,GO:0007339; GO:0005509; GO:0005789; GO:0016021; GO:0005635; GO:0006461; GO:0006457,binding of sperm to zona pellucida; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; nuclear envelope; protein complex assembly; protein folding,PF00262;,2.00E-173,CHOYP_CALX.1.1,,,,,,,CLGN_BOVIN,Bos taurus (Bovine),binding of sperm to zona pellucida [GO:0007339]; protein complex assembly [GO:0006461]; protein folding [GO:0006457] comp142333_c0_seq5,3543,38.95,0.37425865,0,0,,6.00E-180,P27824,Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90),Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90),GO:0007568; GO:0019886; GO:0002474; GO:0030424; GO:0005509; GO:0072583; GO:0032839; GO:0043197; GO:0005788; GO:0071556; GO:0042470; GO:0043025; GO:0043687; GO:0018279; GO:0006457; GO:0009306; GO:0005840; GO:0048488; GO:0051082,aging; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; axon; calcium ion binding; clathrin-mediated endocytosis; dendrite cytoplasm; dendritic spine; endoplasmic reticulum lumen; integral to lumenal side of endoplasmic reticulum membrane; melanosome; neuronal cell body; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding; protein secretion; ribosome; synaptic vesicle endocytosis; unfolded protein binding,PF00262;,4.00E-180,CHOYP_CALX.1.1,,,,,,,CALX_HUMAN,Homo sapiens (Human),aging [GO:0007568]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; chaperone-mediated protein folding [GO:0061077]; clathrin-mediated endocytosis [GO:0072583]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; synaptic vesicle endocytosis [GO:0048488] comp142334_c2_seq1,1021,31.6357,0.58871024,136,1845,,3.00E-06,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,,,3.00E-21,ruditapes_c883,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp142336_c0_seq1,1590,38.805,0.39187208,0,0,,6.00E-46,Q7Z5K2,Wings apart-like protein homolog (Friend of EBNA2 protein),Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor),GO:0051301; GO:0000785; GO:0000775; GO:0008278; GO:0005829; GO:0015630; GO:0007067; GO:0000278; GO:0019048; GO:0008156; GO:0035562; GO:0045875; GO:0005654; GO:0071168; GO:0071922; GO:0009636; GO:0000795,"cell division; chromatin; chromosome, centromeric region; cohesin complex; cytosol; microtubule cytoskeleton; mitosis; mitotic cell cycle; modulation by virus of host morphology or physiology; negative regulation of DNA replication; negative regulation of chromatin binding; negative regulation of sister chromatid cohesion; nucleoplasm; protein localization to chromatin; regulation of cohesin localization to chromatin; response to toxic substance; synaptonemal complex",PF07814;,,,,,,,,,WAPL_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization to chromatin [GO:0071168]; regulation of chromosome condensation [GO:0060623]; regulation of cohesin loading [GO:0071922]; response to toxic substance [GO:0009636]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032] comp142336_c0_seq13,1831,44.8935,0.49954963,0,0,,2.00E-45,Q7Z5K2,Wings apart-like protein homolog (Friend of EBNA2 protein),Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor),GO:0051301; GO:0000785; GO:0000775; GO:0008278; GO:0005829; GO:0015630; GO:0007067; GO:0000278; GO:0019048; GO:0008156; GO:0035562; GO:0045875; GO:0005654; GO:0071168; GO:0071922; GO:0009636; GO:0000795,"cell division; chromatin; chromosome, centromeric region; cohesin complex; cytosol; microtubule cytoskeleton; mitosis; mitotic cell cycle; modulation by virus of host morphology or physiology; negative regulation of DNA replication; negative regulation of chromatin binding; negative regulation of sister chromatid cohesion; nucleoplasm; protein localization to chromatin; regulation of cohesin localization to chromatin; response to toxic substance; synaptonemal complex",PF07814;,3.00E-45,CHOYP_LOC100376151.1.1,,,,,,,WAPL_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization to chromatin [GO:0071168]; regulation of chromosome condensation [GO:0060623]; regulation of cohesin loading [GO:0071922]; response to toxic substance [GO:0009636]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032] comp142336_c0_seq9,2084,44.2898,0.5308046,0,0,,1.00E-68,Q7Z5K2,Wings apart-like protein homolog (Friend of EBNA2 protein),Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor),GO:0051301; GO:0000785; GO:0000775; GO:0008278; GO:0005829; GO:0015630; GO:0007067; GO:0000278; GO:0019048; GO:0008156; GO:0035562; GO:0045875; GO:0005654; GO:0071168; GO:0071922; GO:0009636; GO:0000795,"cell division; chromatin; chromosome, centromeric region; cohesin complex; cytosol; microtubule cytoskeleton; mitosis; mitotic cell cycle; modulation by virus of host morphology or physiology; negative regulation of DNA replication; negative regulation of chromatin binding; negative regulation of sister chromatid cohesion; nucleoplasm; protein localization to chromatin; regulation of cohesin localization to chromatin; response to toxic substance; synaptonemal complex",PF07814;,2.00E-54,CHOYP_LOC100376151.1.1,,,,,,,WAPL_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization to chromatin [GO:0071168]; regulation of chromosome condensation [GO:0060623]; regulation of cohesin loading [GO:0071922]; response to toxic substance [GO:0009636]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032] comp142337_c2_seq1,2177,42.0763,0.47120202,452,3174,,1.00E-176,Q6P1R4,tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 1-like),tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 1-like),GO:0050660; GO:0017150; GO:0002943,flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF01207;,6.00E-112,CHOYP_VPP1.2.2,,,3.00E-78,AM862948.p.cg.6,2,,DUS1L_HUMAN,Homo sapiens (Human), comp142338_c0_seq1,3137,40.7396,0.63406287,28615,179381,,0,Q13310,Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),GO:0006401; GO:0006396; GO:0007596; GO:0010494; GO:0000166; GO:0005634; GO:0008143; GO:0008266; GO:0006412,RNA catabolic process; RNA processing; blood coagulation; cytoplasmic stress granule; nucleotide binding; nucleus; poly(A) RNA binding; poly(U) RNA binding; translation,PF00658;PF00076;,0,CHOYP_PABP4.3.6,2.00E-61,ruditapes2_c2174,,,,,PABP4_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412] comp142339_c0_seq1,3129,37.9674,0.86996272,7,34,,2.00E-106,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,2.00E-31,CHOYP_AAEL_AAEL009387.1.1,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp142339_c0_seq2,3152,38.0711,0.86788519,7,3,,5.00E-101,Q26609,Hexokinase (EC 2.7.1.1),Hexokinase (EC 2.7.1.1),GO:0005524; GO:0006096; GO:0004396,ATP binding; glycolysis; hexokinase activity,PF00349;PF03727;,2.00E-31,CHOYP_LOC657694.1.1,,,,,,,HXK_SCHMA,Schistosoma mansoni (Blood fluke),cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096] comp142339_c0_seq3,385,40.7792,1.22642968,0,0,,,,,,,,,,,4.00E-14,ruditapes_c26081,,,,,,, comp142340_c0_seq1,1543,41.2184,0.43338197,570,1947,,6.00E-65,Q78KK3,Solute carrier family 22 member 18 (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Multi-membrane-spanning polyspecific transporter) (Organic cation transporter-like protein 2) (ORCTL-2),Solute carrier family 22 member 18 (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Multi-membrane-spanning polyspecific transporter) (Organic cation transporter-like protein 2) (ORCTL-2),GO:0016324; GO:0015238; GO:0005887; GO:0005635; GO:0008514; GO:0015293,apical plasma membrane; drug transmembrane transporter activity; integral to plasma membrane; nuclear envelope; organic anion transmembrane transporter activity; symporter activity,PF07690;,5.00E-92,CHOYP_LOC100177728.1.1,,,,,,,S22AI_MOUSE,Mus musculus (Mouse),anion transport [GO:0006820]; drug transport [GO:0015893] comp142341_c0_seq1,1811,43.291,0.47302919,73,139,,0,Q14692,Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog),Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog),GO:0005524; GO:0005730; GO:0042255,ATP binding; nucleolus; ribosome assembly,PF08142;PF04950;,7.00E-180,CHOYP_BMS1.1.1,,,,,,,BMS1_HUMAN,Homo sapiens (Human),"endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]" comp142341_c0_seq2,3888,40.535,0.45196636,100,391,,0,Q14692,Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog),Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog),GO:0005524; GO:0005730; GO:0042255,ATP binding; nucleolus; ribosome assembly,PF08142;PF04950;,0,CHOYP_BMS1.1.1,,,,,,,BMS1_HUMAN,Homo sapiens (Human),"endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]" comp142341_c0_seq3,2798,37.2051,0.43986386,307,1720,,6.00E-158,Q8CHW4,Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon),Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon),GO:0014002; GO:0035690; GO:0005851; GO:0042552; GO:0032057; GO:0005634; GO:0014003; GO:0001541; GO:0045948; GO:0034976; GO:0009749; GO:0009408; GO:0043434; GO:0003743; GO:0006413,astrocyte development; cellular response to drug; eukaryotic translation initiation factor 2B complex; myelination; negative regulation of translational initiation in response to stress; nucleus; oligodendrocyte development; ovarian follicle development; positive regulation of translational initiation; response to endoplasmic reticulum stress; response to glucose stimulus; response to heat; response to peptide hormone stimulus; translation initiation factor activity; translational initiation,PF00132;PF02020;,2.00E-12,CHOYP_LOC579737.1.1,,,,,,,EI2BE_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; astrocyte development [GO:0014002]; astrocyte differentiation [GO:0048708]; cellular response to drug [GO:0035690]; myelination [GO:0042552]; negative regulation of translational initiation in response to stress [GO:0032057]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; positive regulation of translational initiation [GO:0045948]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413] comp142342_c0_seq1,7564,36.7134,0.51934764,207,76,,0,Q5PQT2,Myotubularin-related protein 3 (EC 3.1.3.48),"Myotubularin-related protein 3 (EC 3.1.3.48) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)",GO:0005737; GO:0016020; GO:0046872; GO:0046856; GO:0004438; GO:0004722; GO:0004725,cytoplasm; membrane; metal ion binding; phosphatidylinositol dephosphorylation; phosphatidylinositol-3-phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity,PF01363;PF06602;,2.00E-66,CHOYP_BRAFLDRAFT_219160.1.1,,,,,,,MTMR3_RAT,Rattus norvegicus (Rat),phosphatidylinositol dephosphorylation [GO:0046856] comp142342_c0_seq4,6269,35.6197,0.5065316,6,0,,2.00E-122,Q5PQT2,Myotubularin-related protein 3 (EC 3.1.3.48),"Myotubularin-related protein 3 (EC 3.1.3.48) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)",GO:0005737; GO:0016020; GO:0046872; GO:0046856; GO:0004438; GO:0004722; GO:0004725,cytoplasm; membrane; metal ion binding; phosphatidylinositol dephosphorylation; phosphatidylinositol-3-phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity,PF01363;PF06602;,3.00E-64,CHOYP_BRAFLDRAFT_219160.1.1,,,,,,,MTMR3_RAT,Rattus norvegicus (Rat),phosphatidylinositol dephosphorylation [GO:0046856] comp142347_c0_seq2,1723,35.5775,0.95520639,2,245,female>male,8.00E-17,Q52RN5,Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),GO:0000187; GO:0006309; GO:0060088; GO:0007569; GO:0006879; GO:0051087; GO:0005507; GO:0031410; GO:0005829; GO:0032839; GO:0006302; GO:0007566; GO:0031012; GO:0005615; GO:0006749; GO:0060047; GO:0050665; GO:0007626; GO:0005739; GO:0046716; GO:0002262; GO:0045541; GO:0043524; GO:0060052; GO:0043025; GO:0005634; GO:0001541; GO:0032287; GO:0001819; GO:0043234; GO:0030346; GO:0008217; GO:0051881; GO:0040014; GO:0060087; GO:0019430; GO:0048678; GO:0042493; GO:0045471; GO:0009408; GO:0042542; GO:0001895; GO:0007605; GO:0007283; GO:0004784; GO:0008270,activation of MAPK activity; apoptotic DNA fragmentation; auditory receptor cell stereocilium organization; cell aging; cellular iron ion homeostasis; chaperone binding; copper ion binding; cytoplasmic vesicle; cytosol; dendrite cytoplasm; double-strand break repair; embryo implantation; extracellular matrix; extracellular space; glutathione metabolic process; heart contraction; hydrogen peroxide biosynthetic process; locomotory behavior; mitochondrion; muscle cell cellular homeostasis; myeloid cell homeostasis; negative regulation of cholesterol biosynthetic process; negative regulation of neuron apoptotic process; neurofilament cytoskeleton organization; neuronal cell body; nucleus; ovarian follicle development; peripheral nervous system myelin maintenance; positive regulation of cytokine production; protein complex; protein phosphatase 2B binding; regulation of blood pressure; regulation of mitochondrial membrane potential; regulation of multicellular organism growth; relaxation of vascular smooth muscle; removal of superoxide radicals; response to axon injury; response to drug; response to ethanol; response to heat; response to hydrogen peroxide; retina homeostasis; sensory perception of sound; spermatogenesis; superoxide dismutase activity; zinc ion binding,PF00080;,,,,,,,,,SODC_BOSMU,Bos mutus grunniens (Wild yak) (Bos grunniens),activation of MAPK activity [GO:0000187]; apoptotic DNA fragmentation [GO:0006309]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; double-strand break repair [GO:0006302]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226] comp142349_c0_seq1,3209,43.0975,0.45830188,8,19,,2.00E-33,Q3USH5,"Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)","Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0005634; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09750;PF01805;,,,,,,,,,SFSWA_MOUSE,Mus musculus (Mouse),"alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142349_c0_seq2,3111,43.5551,0.45550157,3,17,,4.00E-27,P12297,Protein suppressor of white apricot,Protein suppressor of white apricot,GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09750;PF01805;,9.00E-42,CHOYP_LOC100716402.1.1,,,,,,,SUWA_DROME,Drosophila melanogaster (Fruit fly),"mRNA 5'-splice site recognition [GO:0000395]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142349_c0_seq4,577,41.0745,0.5385624,5,0,,4.00E-32,D3ZTQ1,"Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)","Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0005634; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09750;PF01805;,2.00E-42,CHOYP_LOC100716402.1.1,,,,,,,SFSWA_RAT,Rattus norvegicus (Rat),"mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142350_c0_seq1,2832,41.3136,0.48227793,923,3448,,1.00E-84,A4IGK4,RNA-binding protein 5 (RNA-binding motif protein 5),RNA-binding protein 5 (RNA-binding motif protein 5),GO:0003729; GO:0000166; GO:0005634; GO:0043065; GO:0000381; GO:0005681; GO:0000245; GO:0008270,"mRNA binding; nucleotide binding; nucleus; positive regulation of apoptotic process; regulation of alternative mRNA splicing, via spliceosome; spliceosomal complex; spliceosomal complex assembly; zinc ion binding",PF01585;PF00076;PF00641;,3.00E-54,CHOYP_RBM10.1.2,,,,,,,RBM5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245]" comp142351_c0_seq1,2117,35.3803,0.49263956,299,2449,,3.00E-11,O75496,Geminin,Geminin,GO:0005829; GO:0000278; GO:0008156; GO:0045786; GO:0045892; GO:0005654; GO:0009887; GO:0006461; GO:0003714,"cytosol; mitotic cell cycle; negative regulation of DNA replication; negative regulation of cell cycle; negative regulation of transcription, DNA-dependent; nucleoplasm; organ morphogenesis; protein complex assembly; transcription corepressor activity",PF07412;,5.00E-11,CHOYP_LOC100313617.1.1,,,,,,,GEMI_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA replication [GO:0008156]; negative regulation of transcription, DNA-templated [GO:0045892]; organ morphogenesis [GO:0009887]; protein complex assembly [GO:0006461]" comp142352_c0_seq6,3786,41.8384,0.41377075,0,0,,8.00E-61,Q9LID0,Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2),Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2),GO:0003677; GO:0051568; GO:0016491; GO:0006355; GO:0006351,"DNA binding; histone H3-K4 methylation; oxidoreductase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01593;PF04433;,0,CHOYP_KDM1A.1.1,,,,,,,LDL2_ARATH,Arabidopsis thaliana (Mouse-ear cress),"histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142352_c0_seq8,4045,40.9394,0.4458016,0,10,,0,Q6ZQ88,Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2),Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2),GO:0050681; GO:0008283; GO:0003682; GO:0050660; GO:0030851; GO:0032454; GO:0034648; GO:0001701; GO:0030374; GO:0055001; GO:0051572; GO:0051573; GO:0043433; GO:0000122; GO:0000790; GO:0016491; GO:0021983; GO:0045648; GO:0046886; GO:0045654; GO:2000179; GO:2000648; GO:0045944; GO:0010725; GO:0034401; GO:0003700; GO:0005667; GO:0044212; GO:0006351,"androgen receptor binding; cell proliferation; chromatin binding; flavin adenine dinucleotide binding; granulocyte differentiation; histone demethylase activity (H3-K9 specific); histone demethylase activity (H3-dimethyl-K4 specific); in utero embryonic development; ligand-dependent nuclear receptor transcription coactivator activity; muscle cell development; negative regulation of histone H3-K4 methylation; negative regulation of histone H3-K9 methylation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; oxidoreductase activity; pituitary gland development; positive regulation of erythrocyte differentiation; positive regulation of hormone biosynthetic process; positive regulation of megakaryocyte differentiation; positive regulation of neural precursor cell proliferation; positive regulation of stem cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of primitive erythrocyte differentiation; regulation of transcription by chromatin organization; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent",PF01593;PF04433;,0,CHOYP_KDM1A.1.1,,,,,,,KDM1A_MOUSE,Mus musculus (Mouse),"cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; granulocyte differentiation [GO:0030851]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; in utero embryonic development [GO:0001701]; muscle cell development [GO:0055001]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neurogenesis [GO:0050768]; negative regulation of protein binding [GO:0032091]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter by histone modification [GO:1903758]; neuron projection extension [GO:1990138]; pituitary gland development [GO:0021983]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of neurogenesis [GO:0050767]; regulation of primitive erythrocyte differentiation [GO:0010725]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142353_c0_seq1,1694,34.9469,0.70576013,285,1683,,1.00E-44,Q5R9W6,Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18),Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18),GO:0003677; GO:0005730; GO:0006355; GO:0005669; GO:0006366,"DNA binding; nucleolus; regulation of transcription, DNA-dependent; transcription factor TFIID complex; transcription from RNA polymerase II promoter",PF02269;,3.00E-57,CHOYP_TAF13.3.3,4.00E-79,ruditapes_c8301,,,,,TAF13_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp142355_c1_seq2,2357,41.0692,0.43566296,38,35,,1.00E-170,Q6P9I7,Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (xSMC6),Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (xSMC6),GO:0005524; GO:0016605; GO:0030915; GO:0090398; GO:0000781; GO:0000724; GO:0000722,"ATP binding; PML body; Smc5-Smc6 complex; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; telomere maintenance via recombination",PF02463;,,,,,,,,,SMC6_XENLA,Xenopus laevis (African clawed frog),cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; resolution of recombination intermediates [GO:0071139]; telomere maintenance via recombination [GO:0000722] comp142355_c1_seq3,1922,40.3746,0.42498957,7,0,,1.00E-11,O13710,Structural maintenance of chromosomes protein 5 (DNA repair protein spr18) (SMC partner of rad18),Structural maintenance of chromosomes protein 5 (DNA repair protein spr18) (SMC partner of rad18),GO:0005524; GO:0030915; GO:0000935; GO:0032153; GO:0005829; GO:0000724; GO:0007126; GO:0044732; GO:0005634; GO:0048478,ATP binding; Smc5-Smc6 complex; barrier septum; cell division site; cytosol; double-strand break repair via homologous recombination; meiosis; mitotic spindle pole body; nucleus; replication fork protection,,1.00E-75,CHOYP_BRAFLDRAFT_131216.1.1,,,,,,,SMC5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062] comp142355_c1_seq4,1573,39.7966,0.48845095,0,0,,5.00E-10,Q802R9,Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5),Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5),GO:0005524; GO:0016605; GO:0030915; GO:0051301; GO:0090398; GO:0000781; GO:0000724; GO:0007067; GO:0034184; GO:0045842; GO:0000722,"ATP binding; PML body; Smc5-Smc6 complex; cell division; cellular senescence; chromosome, telomeric region; double-strand break repair via homologous recombination; mitosis; positive regulation of maintenance of mitotic sister chromatid cohesion; positive regulation of mitotic metaphase/anaphase transition; telomere maintenance via recombination",PF02463;,1.00E-75,CHOYP_BRAFLDRAFT_131216.1.1,,,,,,,SMC5_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722] comp142355_c1_seq5,867,40.8304,0.51781463,41,68,,,,,,,,,7.00E-30,CHOYP_LOC100073775.1.1,,,,,,,,, comp142356_c0_seq2,2597,44.6284,0.41936669,1,14,,0,Q8BZQ7,Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2),Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2),GO:0005680; GO:0030154; GO:0051301; GO:0007067; GO:0007399; GO:0090129; GO:0031915; GO:0070979; GO:0006511,anaphase-promoting complex; cell differentiation; cell division; mitosis; nervous system development; positive regulation of synapse maturation; positive regulation of synaptic plasticity; protein K11-linked ubiquitination; ubiquitin-dependent protein catabolic process,PF08672;PF00888;,,,,,,,,,ANC2_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp142356_c0_seq3,2570,44.4747,0.42675279,4,0,,6.00E-120,Q8H1U5,Anaphase-promoting complex subunit 2 (Cyclosome subunit 2),Anaphase-promoting complex subunit 2 (Cyclosome subunit 2),GO:0051301; GO:0031461; GO:0009561; GO:0007067; GO:0005634; GO:0016567; GO:0005819; GO:0006511,cell division; cullin-RING ubiquitin ligase complex; megagametogenesis; mitosis; nucleus; protein ubiquitination; spindle; ubiquitin-dependent protein catabolic process,PF08672;PF00888;,0,CHOYP_LOC100650613.1.1,,,,,,,APC2_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell division [GO:0051301]; megagametogenesis [GO:0009561]; mitotic nuclear division [GO:0007067]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp142357_c0_seq1,2218,42.5158,0.44027787,268,404,,1.00E-62,O08715,"A-kinase anchor protein 1, mitochondrial (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein) (S-AKAP)","A-kinase anchor protein 1, mitochondrial (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein) (S-AKAP)",GO:0003723; GO:0005783; GO:0016021; GO:0005741; GO:0005739,RNA binding; endoplasmic reticulum; integral to membrane; mitochondrial outer membrane; mitochondrion,PF00013;PF00567;,5.00E-75,CHOYP_PHUM_PHUM233260.1.1,,,,,,,AKAP1_MOUSE,Mus musculus (Mouse),cellular response to cAMP [GO:0071320]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein dephosphorylation [GO:0035308]; regulation of protein kinase A signaling [GO:0010738] comp142358_c1_seq1,3039,32.9056,0.50609274,226,729,,,,,,,,,2.00E-131,CHOYP_BRAFLDRAFT_127851.1.1,8.00E-53,ruditapes_c4801,,,,,,, comp142358_c1_seq4,3056,32.9843,0.51322296,295,1658,,8.00E-98,P49020,Transmembrane emp24 domain-containing protein 2 (COPI-coated vesicle membrane protein p24) (p24 family protein beta-1) (p24beta1) (Fragment),Transmembrane emp24 domain-containing protein 2 (COPI-coated vesicle membrane protein p24) (p24 family protein beta-1) (p24beta1) (Fragment),GO:0030137; GO:0030663; GO:0032580; GO:0007030; GO:0005783; GO:0005789; GO:0005793; GO:0033116; GO:0016021; GO:0034260; GO:0072661; GO:0016192,COPI-coated vesicle; COPI-coated vesicle membrane; Golgi cisterna membrane; Golgi organization; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; negative regulation of GTPase activity; protein targeting to plasma membrane; vesicle-mediated transport,PF01105;,,,1.00E-113,ruditapes_c665,,,,,TMED2_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),Golgi organization [GO:0007030]; negative regulation of GTPase activity [GO:0034260]; protein targeting to plasma membrane [GO:0072661]; vesicle-mediated transport [GO:0016192] comp142361_c1_seq1,1251,27.0184,0.66508524,14,23,,,,,,,,,3.00E-12,CHOYP_contig_008339,,,,,,,,, comp142361_c1_seq5,3799,31.0608,0.46250818,34,144,,1.00E-82,Q5RBA4,"Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)","Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)",GO:0030018; GO:0005509; GO:0016460; GO:0001725,Z disc; calcium ion binding; myosin II complex; stress fiber,PF13405;PF13833;,,,,,,,,,MYL9_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),platelet aggregation [GO:0070527] comp142361_c1_seq7,3763,31.1454,0.46524389,44,87,,1.00E-82,Q5RBA4,"Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)","Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)",GO:0030018; GO:0005509; GO:0016460; GO:0001725,Z disc; calcium ion binding; myosin II complex; stress fiber,PF13405;PF13833;,1.00E-103,CHOYP_LOC100372342.1.1,,,,,,,MYL9_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),platelet aggregation [GO:0070527] comp142364_c1_seq1,2367,34.981,0.58054471,267,1078,,3.00E-97,Q29RL9,Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1),Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1),GO:0003677; GO:0005730; GO:0032784; GO:0006357; GO:0006351; GO:0008270,"DNA binding; nucleolus; regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; zinc ion binding",PF08711;PF01096;PF07500;,3.00E-53,CHOYP_LOC100558815.1.1,,,,,,,TCEA1_BOVIN,Bos taurus (Bovine),"regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142367_c0_seq1,2966,42.7512,0.34694765,1,54,,5.00E-111,Q6PFJ7,Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),GO:0000139; GO:0005789; GO:0016021; GO:0046872; GO:0050290; GO:0004767,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; metal ion binding; sphingomyelin phosphodiesterase D activity; sphingomyelin phosphodiesterase activity,PF14724;,,,,,,,,,NSMA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142367_c0_seq3,2612,42.5727,0.33811351,0,0,,2.00E-117,Q6ZPR5,Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),GO:0005794; GO:0000139; GO:0071356; GO:0046513; GO:0005783; GO:0005789; GO:0046475; GO:0016021; GO:0046872; GO:0006685; GO:0050290; GO:0004767; GO:0005802,Golgi apparatus; Golgi membrane; cellular response to tumor necrosis factor; ceramide biosynthetic process; endoplasmic reticulum; endoplasmic reticulum membrane; glycerophospholipid catabolic process; integral to membrane; metal ion binding; sphingomyelin catabolic process; sphingomyelin phosphodiesterase D activity; sphingomyelin phosphodiesterase activity; trans-Golgi network,PF14724;,7.00E-17,CHOYP_BRAFLDRAFT_128365.1.1,,,,,,,NSMA3_MOUSE,Mus musculus (Mouse),cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; glycerophospholipid catabolic process [GO:0046475]; sphingomyelin catabolic process [GO:0006685] comp142367_c0_seq6,2976,42.7083,0.34647141,18,31,,3.00E-126,Q5XHG1,Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),GO:0000139; GO:0005789; GO:0016021; GO:0046872; GO:0050290; GO:0004767,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; metal ion binding; sphingomyelin phosphodiesterase D activity; sphingomyelin phosphodiesterase activity,PF14724;,,,,,,,,,NSMA3_XENLA,Xenopus laevis (African clawed frog), comp142367_c0_seq7,2623,42.6611,0.33529481,2,0,,2.00E-127,Q5XHG1,Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III),GO:0000139; GO:0005789; GO:0016021; GO:0046872; GO:0050290; GO:0004767,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; metal ion binding; sphingomyelin phosphodiesterase D activity; sphingomyelin phosphodiesterase activity,PF14724;,,,,,,,,,NSMA3_XENLA,Xenopus laevis (African clawed frog), comp142367_c0_seq9,819,43.4676,0.33661791,0,0,,,,,,,,,3.00E-16,CHOYP_BRAFLDRAFT_128365.1.1,,,,,,,,, comp142368_c1_seq1,1536,45.638,0.57913579,0,0,,4.00E-13,Q13310,Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),GO:0006401; GO:0006396; GO:0007596; GO:0010494; GO:0000166; GO:0005634; GO:0008143; GO:0008266; GO:0006412,RNA catabolic process; RNA processing; blood coagulation; cytoplasmic stress granule; nucleotide binding; nucleus; poly(A) RNA binding; poly(U) RNA binding; translation,PF00658;PF00076;,,,,,,,,,PABP4_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412] comp142368_c1_seq10,1517,45.8141,0.58336775,0,0,,2.00E-08,Q9IBD1,CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein),CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0048026,"RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome",PF00076;,,,,,,,,,CELF3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]" comp142368_c1_seq11,2029,44.554,0.51956472,0,0,,6.00E-12,Q6CDH3,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,,,,,,,,,PABP_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of translation [GO:0006417] comp142368_c1_seq12,1432,44.4832,0.54092048,0,0,,3.00E-151,Q5RC80,RNA-binding protein 39 (RNA-binding motif protein 39),RNA-binding protein 39 (RNA-binding motif protein 39),GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15519;PF00076;,1.00E-143,CHOYP_RBM39.1.1,,,,,,,RBM39_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142368_c1_seq13,1471,44.2556,0.56057052,0,12,,7.00E-09,Q7TSY6,CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),GO:0042835; GO:0000380; GO:0005737; GO:0003729; GO:0006376; GO:0090394; GO:0000166; GO:0005634; GO:0048026; GO:0000381,"BRE binding; alternative mRNA splicing, via spliceosome; cytoplasm; mRNA binding; mRNA splice site selection; negative regulation of excitatory postsynaptic membrane potential; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome",PF00076;,,,,,,,,,CELF4_MOUSE,Mus musculus (Mouse),"alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]" comp142368_c1_seq14,1971,44.8503,0.50808721,0,0,,5.00E-13,Q13310,Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),GO:0006401; GO:0006396; GO:0007596; GO:0010494; GO:0000166; GO:0005634; GO:0008143; GO:0008266; GO:0006412,RNA catabolic process; RNA processing; blood coagulation; cytoplasmic stress granule; nucleotide binding; nucleus; poly(A) RNA binding; poly(U) RNA binding; translation,PF00658;PF00076;,,,,,,,,,PABP4_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412] comp142368_c1_seq16,1880,44.0957,0.48479395,0,0,,7.00E-109,Q86U06,Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2),Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2),GO:0003723; GO:0006397; GO:0000166; GO:0005634,RNA binding; mRNA processing; nucleotide binding; nucleus,PF15519;PF00076;,8.00E-135,CHOYP_RBM39.1.1,,,,,,,RBM23_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397] comp142368_c1_seq17,1919,43.877,0.49100021,0,0,,9.00E-09,Q7TSY6,CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4),GO:0042835; GO:0000380; GO:0005737; GO:0003729; GO:0006376; GO:0090394; GO:0000166; GO:0005634; GO:0048026; GO:0000381,"BRE binding; alternative mRNA splicing, via spliceosome; cytoplasm; mRNA binding; mRNA splice site selection; negative regulation of excitatory postsynaptic membrane potential; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome",PF00076;,,,,,,,,,CELF4_MOUSE,Mus musculus (Mouse),"alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]" comp142368_c1_seq18,2163,44.429,0.51663229,0,0,,4.00E-175,Q5RC80,RNA-binding protein 39 (RNA-binding motif protein 39),RNA-binding protein 39 (RNA-binding motif protein 39),GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15519;PF00076;,,,,,,,,,RBM39_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142368_c1_seq2,2105,44.7506,0.51417922,0,0,,6.00E-09,P15771,Nucleolin (Protein C23),Nucleolin (Protein C23),GO:0003677; GO:0003723; GO:0005730; GO:0000166,DNA binding; RNA binding; nucleolus; nucleotide binding,PF00076;,,,,,,,,,NUCL_CHICK,Gallus gallus (Chicken), comp142368_c1_seq3,2065,44.9879,0.50899248,8,52,,8.00E-179,Q5RC80,RNA-binding protein 39 (RNA-binding motif protein 39),RNA-binding protein 39 (RNA-binding motif protein 39),GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15519;PF00076;,,,,,,,,,RBM39_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142368_c1_seq4,1575,45.3333,0.58535821,0,0,,2.00E-08,Q9IBD1,CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein),CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein),GO:0003723; GO:0005737; GO:0006397; GO:0000166; GO:0005634; GO:0048026,"RNA binding; cytoplasm; mRNA processing; nucleotide binding; nucleus; positive regulation of mRNA splicing, via spliceosome",PF00076;,,,,,,,,,CELF3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]" comp142368_c1_seq5,2058,43.586,0.50341797,0,0,,3.00E-11,Q13310,Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP),GO:0006401; GO:0006396; GO:0007596; GO:0010494; GO:0000166; GO:0005634; GO:0008143; GO:0008266; GO:0006412,RNA catabolic process; RNA processing; blood coagulation; cytoplasmic stress granule; nucleotide binding; nucleus; poly(A) RNA binding; poly(U) RNA binding; translation,PF00658;PF00076;,,,,,,,,,PABP4_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412] comp142368_c1_seq7,1478,46.1434,0.57691516,0,0,,1.00E-12,Q5B630,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0006527; GO:0005829; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0008143; GO:1900409; GO:0060213; GO:0006417,arginine catabolic process; cytosol; mRNA processing; mRNA transport; nucleotide binding; nucleus; poly(A) RNA binding; positive regulation of cellular response to oxidative stress; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; regulation of translation,PF00658;PF00076;,,,,,,,,,PABP_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp142368_c1_seq8,2020,43.8119,0.4857565,0,0,,3.00E-179,Q5RC80,RNA-binding protein 39 (RNA-binding motif protein 39),RNA-binding protein 39 (RNA-binding motif protein 39),GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0000166; GO:0006355; GO:0006351,"RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15519;PF00076;,2.00E-174,CHOYP_RBM39.1.1,,,,,,,RBM39_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142368_c1_seq9,2124,44.6328,0.51149716,0,0,,7.00E-10,A2Q848,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0005622; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; intracellular; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,,,,,,,,,PABP_ASPNC,Aspergillus niger (strain CBS 513.88 / FGSC A1513),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp142369_c1_seq2,901,31.5205,0.67113178,53,112,,,,,,,,,,,2.00E-15,ruditapes_c1338,,,,,,, comp142371_c1_seq1,347,46.3977,0.43003137,13,53,,4.00E-42,Q9H3H1,"tRNA dimethylallyltransferase, mitochondrial (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase) (IPTase)","tRNA dimethylallyltransferase, mitochondrial (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase) (IPTase)",GO:0005524; GO:0046872; GO:0005739; GO:0052381; GO:0008033,ATP binding; metal ion binding; mitochondrion; tRNA dimethylallyltransferase activity; tRNA processing,PF01715;PF12171;,,,,,,,,,MOD5_HUMAN,Homo sapiens (Human),mitochondrial tRNA modification [GO:0070900]; tRNA modification [GO:0006400] comp142371_c2_seq19,1441,37.5434,0.53224906,0,0,,2.00E-33,Q969P5,F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx),F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx),GO:0030018; GO:0005634; GO:0016567; GO:0014894,Z disc; nucleus; protein ubiquitination; response to denervation involved in regulation of muscle adaptation,,,,,,,,,,FBX32_HUMAN,Homo sapiens (Human),cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142371_c2_seq28,721,44.6602,0.29993411,46,151,,9.00E-36,Q80UN9,"tRNA dimethylallyltransferase, mitochondrial (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase)","tRNA dimethylallyltransferase, mitochondrial (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase)",GO:0005524; GO:0046872; GO:0005739; GO:0005634; GO:0052381; GO:0008033,ATP binding; metal ion binding; mitochondrion; nucleus; tRNA dimethylallyltransferase activity; tRNA processing,PF01715;PF12171;,,,,,,,,,MOD5_MOUSE,Mus musculus (Mouse),tRNA modification [GO:0006400] comp142371_c2_seq29,1403,42.4804,0.52433738,0,0,,5.00E-50,Q969P5,F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx),F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx),GO:0030018; GO:0005634; GO:0016567; GO:0014894,Z disc; nucleus; protein ubiquitination; response to denervation involved in regulation of muscle adaptation,,,,,,,,,,FBX32_HUMAN,Homo sapiens (Human),cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142371_c2_seq9,1433,38.2415,0.38209451,0,0,,3.00E-29,Q969P5,F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx),F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx),GO:0030018; GO:0005634; GO:0016567; GO:0014894,Z disc; nucleus; protein ubiquitination; response to denervation involved in regulation of muscle adaptation,,,,,,,,,,FBX32_HUMAN,Homo sapiens (Human),cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142373_c0_seq3,1329,36.9451,0.41701529,0,0,,1.00E-11,Q8N0V3,"Putative ribosome-binding factor A, mitochondrial","Putative ribosome-binding factor A, mitochondrial",GO:0005739; GO:0006364,mitochondrion; rRNA processing,PF02033;,,,,,,,,,RBFA_HUMAN,Homo sapiens (Human),rRNA processing [GO:0006364] comp142373_c0_seq8,1344,36.9048,0.41247148,0,0,,1.00E-11,Q8N0V3,"Putative ribosome-binding factor A, mitochondrial","Putative ribosome-binding factor A, mitochondrial",GO:0005739; GO:0006364,mitochondrion; rRNA processing,PF02033;,,,,,,,,,RBFA_HUMAN,Homo sapiens (Human),rRNA processing [GO:0006364] comp142374_c0_seq3,1692,40.1891,0.36639007,0,0,,1.00E-78,Q3TV65,MPN domain-containing protein (EC 3.4.-.-),MPN domain-containing protein (EC 3.4.-.-),GO:0008233; GO:0006508,peptidase activity; proteolysis,PF01398;,1.00E-48,CHOYP_BRAFLDRAFT_221394.1.1,,,,,,,MPND_MOUSE,Mus musculus (Mouse), comp142376_c4_seq1,1910,42.0942,0.46534104,81,632,,3.00E-152,Q8R3L2,Transcription factor 25 (TCF-25) (Nuclear localized protein 1),Transcription factor 25 (TCF-25) (Nuclear localized protein 1),GO:0003677; GO:0005739; GO:0000122; GO:0005730; GO:0005634; GO:0003700; GO:0006351,"DNA binding; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF04910;,3.00E-58,CHOYP_TCF25.1.1,,,,,,,TCF25_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp142376_c4_seq2,973,44.296,0.44049665,0,21,,1.00E-111,Q8R3L2,Transcription factor 25 (TCF-25) (Nuclear localized protein 1),Transcription factor 25 (TCF-25) (Nuclear localized protein 1),GO:0003677; GO:0005739; GO:0000122; GO:0005730; GO:0005634; GO:0003700; GO:0006351,"DNA binding; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF04910;,,,,,,,,,TCF25_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp142379_c0_seq3,2534,34.4909,0.62444978,122,487,,7.00E-19,P52480,Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme),Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme),GO:0005524; GO:0005929; GO:0006096; GO:0000287; GO:0005739; GO:0005634; GO:0030955; GO:0004743,ATP binding; cilium; glycolysis; magnesium ion binding; mitochondrion; nucleus; potassium ion binding; pyruvate kinase activity,PF00224;PF02887;,2.00E-35,CHOYP_KPYM.1.1,,,,,,,KPYM_MOUSE,Mus musculus (Mouse),glycolytic process [GO:0006096]; programmed cell death [GO:0012501] comp142388_c0_seq1,5826,32.8527,0.30050585,5822,23161,,4.00E-44,Q9WU01,"KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (mSLM-1)","KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (mSLM-1)",GO:0042169; GO:0017124; GO:0005070; GO:0005634; GO:0008143; GO:0008266; GO:0046982; GO:0006355; GO:0006351,"SH2 domain binding; SH3 domain binding; SH3/SH2 adaptor activity; nucleus; poly(A) RNA binding; poly(U) RNA binding; protein heterodimerization activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00013;PF16274;PF16568;,6.00E-41,CHOYP_KHDR1.1.1,,,,,,,KHDR2_MOUSE,Mus musculus (Mouse),"regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142390_c0_seq1,1163,47.4635,0.41276626,12,112,,4.00E-06,P18061,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALM_TRYCR,Trypanosoma cruzi, comp142390_c0_seq2,1064,45.5827,0.43620763,15,55,,3.00E-50,Q9UBV8,Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1),Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1),GO:0005509; GO:0005737; GO:0016020; GO:0051592,calcium ion binding; cytoplasm; membrane; response to calcium ion,PF13405;PF13499;,2.00E-44,CHOYP_LOC100367378.1.1,6.00E-17,ruditapes_c1980,,,,,PEF1_HUMAN,Homo sapiens (Human),proteolysis [GO:0006508]; response to calcium ion [GO:0051592] comp142395_c0_seq1,1630,44.908,0.47220632,46,6,,0,P83829,Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1),Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1),GO:0030154; GO:0007275; GO:0007283,cell differentiation; multicellular organismal development; spermatogenesis,,5.00E-162,CHOYP_LOC100366734.1.1,,,,,,,IFT81_RAT,Rattus norvegicus (Rat),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; spermatogenesis [GO:0007283] comp142395_c0_seq2,1657,44.9004,0.46508417,50,4,,0,P83829,Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1),Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1),GO:0030154; GO:0007275; GO:0007283,cell differentiation; multicellular organismal development; spermatogenesis,,,,,,,,,,IFT81_RAT,Rattus norvegicus (Rat),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; spermatogenesis [GO:0007283] comp142396_c0_seq1,2812,42.5676,0.43668294,585,2002,,0,O55096,Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B),Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B),GO:0004177; GO:0005737; GO:0008239; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; dipeptidyl-peptidase activity; metallopeptidase activity; proteolysis; zinc ion binding,,0,CHOYP_LOC582874.1.1,,,,,,,DPP3_RAT,Rattus norvegicus (Rat),proteolysis [GO:0006508] comp142401_c0_seq1,5268,40.7365,0.66480716,2063,12673,,1.00E-53,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,,,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp142401_c0_seq2,5053,40.5106,0.68601135,84,9113,female>male,9.00E-54,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,2.00E-20,CHOYP_MBCDH18.1.1,2.00E-38,ruditapes_c29089,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp142401_c1_seq1,2501,39.0644,0.53654874,25555,145190,,0,Q8JFP1,Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2),Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2),GO:0005524; GO:0008026; GO:0003743,ATP binding; ATP-dependent helicase activity; translation initiation factor activity,PF00270;PF00271;,0,CHOYP_LOC100369745.1.1,2.00E-84,ruditapes_c8263,,,,,IF4A2_CHICK,Gallus gallus (Chicken),regulation of gene expression [GO:0010468]; regulation of translational initiation [GO:0006446]; RNA secondary structure unwinding [GO:0010501]; translational initiation [GO:0006413] comp142404_c0_seq1,2168,43.1273,0.42767818,90,353,,2.00E-116,P11387,DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I),DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I),GO:0005524; GO:0003677; GO:0006260; GO:0003917; GO:0003918; GO:0006265; GO:0003682; GO:0006338; GO:0007059; GO:0000932; GO:0040016; GO:0019048; GO:0005730; GO:0005654; GO:0043204; GO:0016310; GO:0012501; GO:0031298; GO:0042493,ATP binding; DNA binding; DNA replication; DNA topoisomerase type I activity; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; chromatin binding; chromatin remodeling; chromosome segregation; cytoplasmic mRNA processing body; embryonic cleavage; modulation by virus of host morphology or physiology; nucleolus; nucleoplasm; perikaryon; phosphorylation; programmed cell death; replication fork protection complex; response to drug,PF14370;PF01028;PF02919;,2.00E-142,CHOYP_TOP1.5.5,,,,,,,TOP1_HUMAN,Homo sapiens (Human),chromatin remodeling [GO:0006338]; chromosome segregation [GO:0007059]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA replication [GO:0006260]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; phosphorylation [GO:0016310]; programmed cell death [GO:0012501]; protein sumoylation [GO:0016925]; response to drug [GO:0042493]; viral process [GO:0016032] comp142404_c0_seq2,1519,42.3963,0.373178,19,30,,3.00E-119,P11387,DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I),DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I),GO:0005524; GO:0003677; GO:0006260; GO:0003917; GO:0003918; GO:0006265; GO:0003682; GO:0006338; GO:0007059; GO:0000932; GO:0040016; GO:0019048; GO:0005730; GO:0005654; GO:0043204; GO:0016310; GO:0012501; GO:0031298; GO:0042493,ATP binding; DNA binding; DNA replication; DNA topoisomerase type I activity; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; chromatin binding; chromatin remodeling; chromosome segregation; cytoplasmic mRNA processing body; embryonic cleavage; modulation by virus of host morphology or physiology; nucleolus; nucleoplasm; perikaryon; phosphorylation; programmed cell death; replication fork protection complex; response to drug,PF14370;PF01028;PF02919;,,,,,,,,,TOP1_HUMAN,Homo sapiens (Human),chromatin remodeling [GO:0006338]; chromosome segregation [GO:0007059]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA replication [GO:0006260]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; phosphorylation [GO:0016310]; programmed cell death [GO:0012501]; protein sumoylation [GO:0016925]; response to drug [GO:0042493]; viral process [GO:0016032] comp142404_c0_seq3,1805,35.2355,0.41145077,140,773,,3.00E-104,Q969P6,"DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.99.1.2)","DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.99.1.2)",GO:0005524; GO:0003677; GO:0006260; GO:0003917; GO:0003918; GO:0006265; GO:0005694; GO:0042645,ATP binding; DNA binding; DNA replication; DNA topoisomerase type I activity; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; chromosome; mitochondrial nucleoid,PF14370;PF01028;PF02919;,,,,,,,,,TOP1M_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA topological change [GO:0006265] comp142405_c0_seq1,1845,40.6504,0.95548682,58,2044,,9.00E-53,O35490,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,6.00E-35,CHOYP_LOC100371248.2.2,,,,,,,BHMT1_MOUSE,Mus musculus (Mouse),amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086] comp142405_c0_seq3,2203,39.7186,0.92728764,0,24,,,,,,,,,1.00E-31,CHOYP_BRAFLDRAFT_90098.1.4,,,,,,,,, comp142407_c0_seq2,4767,37.6757,0.41762861,2,0,,0,Q8N960,Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),GO:0030953; GO:0005813; GO:0021987; GO:0005737; GO:0022027; GO:0022008; GO:0032886; GO:0032880,astral microtubule organization; centrosome; cerebral cortex development; cytoplasm; interkinetic nuclear migration; neurogenesis; regulation of microtubule-based process; regulation of protein localization,PF00168;PF12416;,2.00E-129,CHOYP_CE120.1.2,,,,,,,CE120_HUMAN,Homo sapiens (Human),astral microtubule organization [GO:0030953]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; regulation of protein localization [GO:0032880] comp142407_c0_seq6,3087,36.8643,0.47364238,2,0,,,,,,,,,1.00E-129,CHOYP_CE120.1.2,,,,,,,,, comp142407_c0_seq8,4754,37.7366,0.41742751,12,16,,0,Q8N960,Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),GO:0030953; GO:0005813; GO:0021987; GO:0005737; GO:0022027; GO:0022008; GO:0032886; GO:0032880,astral microtubule organization; centrosome; cerebral cortex development; cytoplasm; interkinetic nuclear migration; neurogenesis; regulation of microtubule-based process; regulation of protein localization,PF00168;PF12416;,,,,,,,,,CE120_HUMAN,Homo sapiens (Human),astral microtubule organization [GO:0030953]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; regulation of protein localization [GO:0032880] comp142408_c1_seq2,1479,36.1055,0.57475754,120,511,,3.00E-35,Q91WK5,"Glycine cleavage system H protein, mitochondrial","Glycine cleavage system H protein, mitochondrial (Lipoic acid-containing protein)",GO:0004047; GO:0005960; GO:0019464; GO:0005739,aminomethyltransferase activity; glycine cleavage complex; glycine decarboxylation via glycine cleavage system; mitochondrion,PF01597;,,,,,,,,,GCSH_MOUSE,Mus musculus (Mouse),glycine decarboxylation via glycine cleavage system [GO:0019464] comp142411_c0_seq2,773,28.0724,0.59386289,33,54,,4.00E-24,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,1.00E-32,CHOYP_LOC100537145.2.3,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp142413_c0_seq1,716,44.6927,0.39266232,0,8,,,,,,,,,3.00E-47,CHOYP_GCP5.1.1,,,,,,,,, comp142413_c0_seq3,1389,43.6285,0.40978795,0,0,,2.00E-86,Q95K09,Gamma-tubulin complex component 5 (GCP-5) (Fragment),Gamma-tubulin complex component 5 (GCP-5) (Fragment),GO:0008274; GO:0005874; GO:0008017; GO:0007020; GO:0000922,gamma-tubulin ring complex; microtubule; microtubule binding; microtubule nucleation; spindle pole,PF04130;,,,,,,,,,GCP5_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),microtubule nucleation [GO:0007020] comp142413_c0_seq5,1122,44.2068,0.43961671,0,4,,2.00E-19,Q96RT7,Gamma-tubulin complex component 6 (GCP-6),Gamma-tubulin complex component 6 (GCP-6),GO:0000086; GO:0005813; GO:0005829; GO:0008274; GO:0005874; GO:0008017; GO:0007020; GO:0000922,G2/M transition of mitotic cell cycle; centrosome; cytosol; gamma-tubulin ring complex; microtubule; microtubule binding; microtubule nucleation; spindle pole,PF04130;,4.00E-47,CHOYP_GCP5.1.1,,,,,,,GCP6_HUMAN,Homo sapiens (Human),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307] comp142414_c0_seq1,1791,38.0235,0.42748105,437,1394,,5.00E-13,Q8BK72,"28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt)","28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF10037;,,,,,,,,,RT27_MOUSE,Mus musculus (Mouse), comp142415_c0_seq1,3210,37.3209,0.55992378,464,423,,0,Q60737,Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1),Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1),GO:0005524; GO:0016581; GO:0031519; GO:0016580; GO:0016055; GO:0008013; GO:0071174; GO:0043154; GO:0030177; GO:0030307; GO:0008284; GO:0045732; GO:0046777; GO:0005956; GO:0019888; GO:0004674; GO:0006355; GO:0006351,"ATP binding; NuRD complex; PcG protein complex; Sin3 complex; Wnt receptor signaling pathway; beta-catenin binding; mitotic spindle checkpoint; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of Wnt receptor signaling pathway; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of protein catabolic process; protein autophosphorylation; protein kinase CK2 complex; protein phosphatase regulator activity; protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;,0,CHOYP_CSK21.1.2,,,,,,,CSK21_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; mitotic spindle checkpoint [GO:0071174]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]" comp142416_c0_seq6,506,42.8854,0.56256621,138,381,,9.00E-54,Q567Y6,Rab-like protein 5,Intraflagellar transport protein 22 homolog (Rab-like protein 5),GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF08477;,2.00E-35,CHOYP_NEMVEDRAFT_V1G167835.1.1,1.00E-105,ruditapes_c8312,,,,,RABL5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),small GTPase mediated signal transduction [GO:0007264] comp142417_c0_seq1,2120,33.3962,0.4238915,41,178,,3.00E-39,Q7T0T2,Ragulator complex protein LAMTOR3-B (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-B) (Mitogen-activated protein kinase scaffold protein 1),Ragulator complex protein LAMTOR3-B (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-B) (Mitogen-activated protein kinase scaffold protein 1),GO:0071986; GO:0034613; GO:0071230; GO:0032008,Ragulator complex; cellular protein localization; cellular response to amino acid stimulus; positive regulation of TOR signaling cascade,PF08923;,,,2.00E-78,ruditapes2_c594,,,,,LTR3B_XENLA,Xenopus laevis (African clawed frog),cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008] comp142417_c0_seq4,2104,33.5551,0.44035895,4,34,,3.00E-39,Q7T0T2,Ragulator complex protein LAMTOR3-B (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-B) (Mitogen-activated protein kinase scaffold protein 1),Ragulator complex protein LAMTOR3-B (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-B) (Mitogen-activated protein kinase scaffold protein 1),GO:0071986; GO:0034613; GO:0071230; GO:0032008,Ragulator complex; cellular protein localization; cellular response to amino acid stimulus; positive regulation of TOR signaling cascade,PF08923;,,,,,,,,,LTR3B_XENLA,Xenopus laevis (African clawed frog),cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008] comp142420_c0_seq1,1700,38.2353,0.4220684,1393,228,,3.00E-63,Q9YGL1,Speedy protein 1-B (Spy1-B) (Protein Ls27) (Rapid inducer of G2/M progression in oocytes B) (RINGO-B) (XSpy1-B) (p33 ringo-B) (xRINGO-B),Speedy protein 1-B (Spy1-B) (Protein Ls27) (Rapid inducer of G2/M progression in oocytes B) (RINGO-B) (XSpy1-B) (p33 ringo-B) (xRINGO-B),GO:0000187; GO:0030332; GO:0006378; GO:0008315; GO:0007275; GO:0005634; GO:0001556; GO:0045737; GO:0051446,activation of MAPK activity; cyclin binding; mRNA polyadenylation; meiotic G2/MI transition; multicellular organismal development; nucleus; oocyte maturation; positive regulation of cyclin-dependent protein kinase activity; positive regulation of meiotic cell cycle,PF11357;,3.00E-45,CHOYP_LOC100488624.1.1,,,,,,,SPD1B_XENLA,Xenopus laevis (African clawed frog),activation of MAPK activity [GO:0000187]; meiotic G2/MI transition [GO:0008315]; mRNA polyadenylation [GO:0006378]; multicellular organism development [GO:0007275]; oocyte maturation [GO:0001556]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of meiotic cell cycle [GO:0051446] comp142421_c1_seq2,719,37.5522,0.63213467,141,1006,,1.00E-13,Q8TF20,Zinc finger protein 721,Zinc finger protein 721,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN721_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142423_c1_seq1,3914,41.2621,0.7893826,9,0,,0,Q7KZI7,Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b),Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b),GO:0005524; GO:0016055; GO:0045180; GO:0030010; GO:0045197; GO:0007243; GO:0008289; GO:0000287; GO:0016020; GO:0001764; GO:0005634; GO:0005886; GO:0010976; GO:0046777; GO:0004674; GO:0050770; GO:0051493; GO:0050321,ATP binding; Wnt receptor signaling pathway; basal cortex; establishment of cell polarity; establishment or maintenance of epithelial cell apical/basal polarity; intracellular protein kinase cascade; lipid binding; magnesium ion binding; membrane; neuron migration; nucleus; plasma membrane; positive regulation of neuron projection development; protein autophosphorylation; protein serine/threonine kinase activity; regulation of axonogenesis; regulation of cytoskeleton organization; tau-protein kinase activity,PF02149;PF00069;PF00627;,0,CHOYP_ISCW_ISCW014579.1.2,,,,,,,MARK2_HUMAN,Homo sapiens (Human),activation of protein kinase activity [GO:0032147]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; mitochondrion localization [GO:0051646]; mitophagy [GO:0000422]; neuron migration [GO:0001764]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; Wnt signaling pathway [GO:0016055] comp142423_c1_seq14,3924,41.2334,0.79453446,0,0,,3.00E-170,O08679,Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2),Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2),GO:0005524; GO:0016055; GO:0005737; GO:0030010; GO:0045197; GO:0007243; GO:0008289; GO:0000287; GO:0016020; GO:0001764; GO:0005886; GO:0010976; GO:0046777; GO:0004674; GO:0050770; GO:0051493; GO:0050321,ATP binding; Wnt receptor signaling pathway; cytoplasm; establishment of cell polarity; establishment or maintenance of epithelial cell apical/basal polarity; intracellular protein kinase cascade; lipid binding; magnesium ion binding; membrane; neuron migration; plasma membrane; positive regulation of neuron projection development; protein autophosphorylation; protein serine/threonine kinase activity; regulation of axonogenesis; regulation of cytoskeleton organization; tau-protein kinase activity,PF02149;PF00069;PF00627;,0,CHOYP_ISCW_ISCW014579.1.2,,,,,,,MARK2_RAT,Rattus norvegicus (Rat),establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; Wnt signaling pathway [GO:0016055] comp142423_c1_seq18,1158,38.6874,0.75175895,0,0,,1.00E-85,P52497,Carbon catabolite-derepressing protein kinase (EC 2.7.11.1),Carbon catabolite-derepressing protein kinase (EC 2.7.11.1),GO:0005524; GO:0005975; GO:0031965; GO:0004674,ATP binding; carbohydrate metabolic process; nuclear membrane; protein serine/threonine kinase activity,PF16579;PF00069;PF08587;,0,CHOYP_ISCW_ISCW014579.2.2,,,,,,,SNF1_CANAX,Candida albicans (Yeast),carbohydrate metabolic process [GO:0005975] comp142423_c1_seq22,1906,42.9696,0.76243606,0,0,,0,Q03141,MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10),MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10),GO:0005524; GO:0005886; GO:0004674,ATP binding; plasma membrane; protein serine/threonine kinase activity,PF02149;PF00069;PF00627;,,,,,,,,,MARK3_MOUSE,Mus musculus (Mouse), comp142423_c1_seq24,2758,42.8209,0.79186505,0,0,,4.00E-62,Q03141,MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10),MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10),GO:0005524; GO:0005886; GO:0004674,ATP binding; plasma membrane; protein serine/threonine kinase activity,PF02149;PF00069;PF00627;,,,,,,,,,MARK3_MOUSE,Mus musculus (Mouse), comp142423_c1_seq3,3882,41.2674,0.80128823,0,0,,3.00E-25,P24100,Cyclin-dependent kinase A-1 (CDKA;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog A),Cyclin-dependent kinase A-1 (CDKA;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog A),GO:0005524; GO:0042023; GO:0008353; GO:0008356; GO:0010005; GO:0004693; GO:0005829; GO:0009793; GO:0007067; GO:0005634; GO:0005886; GO:0009555; GO:0008284; GO:0009574; GO:0040020; GO:0009409,"ATP binding; DNA endoreduplication; RNA polymerase II carboxy-terminal domain kinase activity; asymmetric cell division; cortical microtubule, transverse to long axis; cyclin-dependent protein serine/threonine kinase activity; cytosol; embryo development ending in seed dormancy; mitosis; nucleus; plasma membrane; pollen development; positive regulation of cell proliferation; preprophase band; regulation of meiosis; response to cold",PF00069;,,,,,,,,,CDKA1_ARATH,Arabidopsis thaliana (Mouse-ear cress),asymmetric cell division [GO:0008356]; cytokinesis by cell plate formation [GO:0000911]; DNA endoreduplication [GO:0042023]; embryo development ending in seed dormancy [GO:0009793]; gametophyte development [GO:0048229]; mitotic nuclear division [GO:0007067]; pollen development [GO:0009555]; positive regulation of cell proliferation [GO:0008284]; regulation of meiotic nuclear division [GO:0040020]; response to cold [GO:0009409] comp142423_c1_seq4,1324,38.3686,0.6691923,0,0,,9.00E-112,Q8CFH6,Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2),Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2),GO:0005524; GO:0005737; GO:0008286; GO:0007243; GO:0000287; GO:0005634; GO:0046777; GO:0004674; GO:0046626,ATP binding; cytoplasm; insulin receptor signaling pathway; intracellular protein kinase cascade; magnesium ion binding; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; regulation of insulin receptor signaling pathway,PF00069;,0,CHOYP_ISCW_ISCW014579.2.2,,,,,,,SIK2_MOUSE,Mus musculus (Mouse),insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] comp142423_c1_seq7,1916,42.8497,0.76270211,0,0,,2.00E-178,O08679,Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2),Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2),GO:0005524; GO:0016055; GO:0005737; GO:0030010; GO:0045197; GO:0007243; GO:0008289; GO:0000287; GO:0016020; GO:0001764; GO:0005886; GO:0010976; GO:0046777; GO:0004674; GO:0050770; GO:0051493; GO:0050321,ATP binding; Wnt receptor signaling pathway; cytoplasm; establishment of cell polarity; establishment or maintenance of epithelial cell apical/basal polarity; intracellular protein kinase cascade; lipid binding; magnesium ion binding; membrane; neuron migration; plasma membrane; positive regulation of neuron projection development; protein autophosphorylation; protein serine/threonine kinase activity; regulation of axonogenesis; regulation of cytoskeleton organization; tau-protein kinase activity,PF02149;PF00069;PF00627;,0,CHOYP_ISCW_ISCW014579.1.2,,,,,,,MARK2_RAT,Rattus norvegicus (Rat),establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; Wnt signaling pathway [GO:0016055] comp142423_c1_seq8,3873,41.3116,0.8014369,5,0,,7.00E-134,Q8VHJ5,Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif serine/threonine-protein kinase 3) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (mPar-1c),Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif serine/threonine-protein kinase 3) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (mPar-1c),GO:0005524; GO:0016055; GO:0005737; GO:0005856; GO:0007243; GO:0000287; GO:0001764; GO:0070300; GO:0005546; GO:0001786; GO:0005886; GO:0004674; GO:0050321,"ATP binding; Wnt receptor signaling pathway; cytoplasm; cytoskeleton; intracellular protein kinase cascade; magnesium ion binding; neuron migration; phosphatidic acid binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; plasma membrane; protein serine/threonine kinase activity; tau-protein kinase activity",PF02149;PF00069;PF00627;,,,,,,,,,MARK1_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] comp142424_c2_seq1,3060,46.4379,0.64475724,15,1347,,5.00E-69,O75369,Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP),Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP),GO:0030018; GO:0003779; GO:0015629; GO:0030036; GO:0005938; GO:0030154; GO:0019221; GO:0007016; GO:0005829; GO:0005925; GO:0016021; GO:0005886; GO:0007519; GO:0001725,Z disc; actin binding; actin cytoskeleton; actin cytoskeleton organization; cell cortex; cell differentiation; cytokine-mediated signaling pathway; cytoskeletal anchoring at plasma membrane; cytosol; focal adhesion; integral to membrane; plasma membrane; skeletal muscle tissue development; stress fiber,PF00307;PF00630;,3.00E-130,CHOYP_LOC100369791.2.2,,,2.00E-95,CU995837.p.cg.6,2,,FLNB_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519] comp142425_c0_seq1,2302,36.4031,0.45011247,20,51,,2.00E-89,P61222,ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I),ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I),GO:0005524; GO:0006200; GO:0016887; GO:0051536; GO:0005739,ATP binding; ATP catabolic process; ATPase activity; iron-sulfur cluster binding; mitochondrion,PF00005;PF00037;PF04068;,,,,,,,,,ABCE1_MOUSE,Mus musculus (Mouse),ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415] comp142425_c0_seq2,2291,36.4906,0.45012832,0,6,,1.00E-30,Q9M0D0,ABC transporter E family member 3 (ABC transporter ABCE.3) (AtABCE3) (MRP-related protein 4) (Non-intrinsic ABC protein 15) (AtNAP15) (RNase L inhibitor-like protein 3) (AthaRLI3),ABC transporter E family member 3 (ABC transporter ABCE.3) (AtABCE3) (MRP-related protein 4) (Non-intrinsic ABC protein 15) (AtNAP15) (RNase L inhibitor-like protein 3) (AthaRLI3),GO:0005524; GO:0006200; GO:0016887; GO:0005215,ATP binding; ATP catabolic process; ATPase activity; transporter activity,PF00005;,,,,,,,,,AB3E_ARATH,Arabidopsis thaliana (Mouse-ear cress),ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415] comp142425_c0_seq4,1557,44.7013,0.54437479,173,354,,0,P61222,ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I),ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I),GO:0005524; GO:0006200; GO:0016887; GO:0051536; GO:0005739,ATP binding; ATP catabolic process; ATPase activity; iron-sulfur cluster binding; mitochondrion,PF00005;PF00037;PF04068;,0,CHOYP_ABCE1.1.2,,,,,,,ABCE1_MOUSE,Mus musculus (Mouse),ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415] comp142426_c1_seq1,1991,36.9161,0.3692336,202,734,,3.00E-69,Q1LZA4,Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-),Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-),GO:0006506; GO:0005789; GO:0016021; GO:0016746,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups",PF06423;,,,,,,,,,PIGW_BOVIN,Bos taurus (Bovine),GPI anchor biosynthetic process [GO:0006506]; protein localization to plasma membrane [GO:0072659] comp142429_c0_seq2,2483,42.8111,0.38691595,67,470,,3.00E-16,Q6P773,"TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)","TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)",GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,TAF1C_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase I promoter [GO:0006360]" comp142431_c0_seq1,1534,36.1799,0.43894786,5,72,,,,,,,,,2.00E-115,CHOYP_RPB7.1.1,,,,,,,,, comp142431_c0_seq2,1550,36.1935,0.43417756,40,92,,7.00E-111,P62489,DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G),DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G),GO:0005665; GO:0003899; GO:0003723; GO:0006915; GO:0006366,"DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; RNA binding; apoptotic process; transcription from RNA polymerase II promoter",PF00575;PF03876;,2.00E-115,CHOYP_RPB7.1.1,2.00E-132,ruditapes2_c1779,7.00E-124,CU986637.p.cg.6,8,,RPB7_RAT,Rattus norvegicus (Rat),"apoptotic process [GO:0006915]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp142431_c2_seq1,2634,41.9514,0.47708171,499,1174,,0,Q08E38,Pre-mRNA-processing factor 19 (PRP19/PSO4 homolog),Pre-mRNA-processing factor 19 (EC 6.3.2.-) (PRP19/PSO4 homolog),GO:0003677; GO:0006281; GO:0000974; GO:0071013; GO:0001833; GO:0008610; GO:0005811; GO:0000398; GO:0045665; GO:0016607; GO:0005634; GO:0048711; GO:0048026; GO:0000209; GO:0005819; GO:0000245; GO:0000151; GO:0034450,"DNA binding; DNA repair; Prp19 complex; catalytic step 2 spliceosome; inner cell mass cell proliferation; lipid biosynthetic process; lipid particle; mRNA splicing, via spliceosome; negative regulation of neuron differentiation; nuclear speck; nucleus; positive regulation of astrocyte differentiation; positive regulation of mRNA splicing, via spliceosome; protein polyubiquitination; spindle; spliceosomal complex assembly; ubiquitin ligase complex; ubiquitin-ubiquitin ligase activity",PF08606;PF04564;PF00400;,0,CHOYP_LOC100376500.1.1,,,,,,,PRP19_BOVIN,Bos taurus (Bovine),"cellular protein localization [GO:0034613]; double-strand break repair via nonhomologous end joining [GO:0006303]; inner cell mass cell proliferation [GO:0001833]; lipid biosynthetic process [GO:0008610]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; proteasomal protein catabolic process [GO:0010498]; protein K63-linked ubiquitination [GO:0070534]; signal transduction involved in DNA damage checkpoint [GO:0072422]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp142432_c0_seq1,1522,35.2168,0.59937059,54,122,,8.00E-45,Q6UX40,Transmembrane protein 107,Transmembrane protein 107,GO:0042384; GO:0042733; GO:0016021; GO:0021532,cilium assembly; embryonic digit morphogenesis; integral to membrane; neural tube patterning,PF14995;,3.00E-18,CHOYP_ISCW_ISCW012049.1.1,,,,,,,TM107_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; embryonic digit morphogenesis [GO:0042733]; neural tube patterning [GO:0021532]; nonmotile primary cilium assembly [GO:0035058] comp142432_c0_seq2,1138,34.71,0.53524477,0,3,,,,,,,,,1.00E-10,CHOYP_TM107.1.1,,,,,,,,, comp142433_c0_seq1,2227,39.2905,0.37524218,50,111,,9.00E-33,Q4PG15,SWR1-complex protein 4,SWR1-complex protein 4,GO:0006281; GO:0035267; GO:0003682; GO:0006338; GO:0043968; GO:0043967; GO:0006355; GO:0006351,"DNA repair; NuA4 histone acetyltransferase complex; chromatin binding; chromatin remodeling; histone H2A acetylation; histone H4 acetylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16282;,,,,,,,,,SWC4_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),"DNA repair [GO:0006281]; histone exchange [GO:0043486]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142433_c0_seq2,2212,39.3309,0.36518937,16,153,,1.00E-164,Q9NPF5,DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1),DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1),GO:0006306; GO:0006281; GO:0035267; GO:0001103; GO:0003682; GO:0006338; GO:0005737; GO:0043968; GO:0043967; GO:0000122; GO:0042993; GO:0040008; GO:0005657; GO:0003714; GO:0006351,"DNA methylation; DNA repair; NuA4 histone acetyltransferase complex; RNA polymerase II repressing transcription factor binding; chromatin binding; chromatin remodeling; cytoplasm; histone H2A acetylation; histone H4 acetylation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor import into nucleus; regulation of growth; replication fork; transcription corepressor activity; transcription, DNA-dependent",PF05499;PF16282;,0,CHOYP_BRAFLDRAFT_93876.1.1,,,,,,,DMAP1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription factor import into nucleus [GO:0042993]; regulation of growth [GO:0040008]; response to ethanol [GO:0045471]; transcription, DNA-templated [GO:0006351]" comp142436_c0_seq2,2057,37.2873,1.02471888,9,147,,5.00E-44,Q04666,Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy-like protein) (RHL),Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy-like protein) (RHL),GO:0071820; GO:0001078; GO:0007262; GO:0021861; GO:2000978; GO:0060253; GO:0048715; GO:2000974; GO:0097150; GO:0005654; GO:0043388; GO:0048711; GO:0042517; GO:0006461; GO:0042803; GO:0043565,N-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; STAT protein import into nucleus; forebrain radial glial cell differentiation; negative regulation of forebrain neuron differentiation; negative regulation of glial cell proliferation; negative regulation of oligodendrocyte differentiation; negative regulation of pro-B cell differentiation; neuronal stem cell maintenance; nucleoplasm; positive regulation of DNA binding; positive regulation of astrocyte differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein; protein complex assembly; protein homodimerization activity; sequence-specific DNA binding,PF07527;PF00010;,6.00E-17,CHOYP_HES1.1.3,,,,,,,HES1_RAT,Rattus norvegicus (Rat),"cellular response to fatty acid [GO:0071398]; cellular response to interleukin-1 [GO:0071347]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; forebrain radial glial cell differentiation [GO:0021861]; hair cell differentiation [GO:0035315]; negative regulation of calcium ion import [GO:0090281]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; neuron differentiation [GO:0030182]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; protein complex assembly [GO:0006461]; regulation of protein heterodimerization activity [GO:0043497]; response to alkaloid [GO:0043279]; response to organic cyclic compound [GO:0014070]; response to thyroid hormone [GO:0097066]; STAT protein import into nucleus [GO:0007262]; transcription, DNA-templated [GO:0006351]" comp142437_c0_seq1,1309,41.1765,0.40097973,2,0,,4.00E-89,Q6GYP7,Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating RapGAP domain-like 1) (Tuberin-like protein 1) (p240),Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating RapGAP domain-like 1) (Tuberin-like protein 1) (p240),GO:0017123; GO:0032859; GO:0005829; GO:0005634; GO:0006355,"Ral GTPase activator activity; activation of Ral GTPase activity; cytosol; nucleus; regulation of transcription, DNA-dependent",PF02145;,1.00E-73,CHOYP_RGPA2.1.1,,,,,,,RGPA1_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of transcription, DNA-templated [GO:0006355]" comp142437_c0_seq2,1336,41.0928,0.39432148,16,11,,9.00E-80,Q2PPJ7,Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220),Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220),GO:0017123; GO:0032484; GO:0032859; GO:0005829; GO:0005634; GO:0046982; GO:0060178,Ral GTPase activator activity; Ral protein signal transduction; activation of Ral GTPase activity; cytosol; nucleus; protein heterodimerization activity; regulation of exocyst localization,PF02145;,,,,,,,,,RGPA2_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] comp142437_c1_seq3,2126,39.6049,0.40816819,118,112,,3.00E-128,Q6GYQ0,Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240),Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240),GO:0017123; GO:0032859; GO:0005829; GO:0005739; GO:0005634; GO:0006355,"Ral GTPase activator activity; activation of Ral GTPase activity; cytosol; mitochondrion; nucleus; regulation of transcription, DNA-dependent",PF02145;,7.00E-136,CHOYP_RGPA1.1.1,,,1.00E-70,AM864624.p.cg.6,1,,RGPA1_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of transcription, DNA-templated [GO:0006355]" comp142437_c1_seq5,2018,43.2111,0.26576007,2,0,,2.00E-76,O55007,Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating RapGAP domain-like 1) (Tuberin-like protein 1) (p240),Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating RapGAP domain-like 1) (Tuberin-like protein 1) (p240),GO:0017123; GO:0032859; GO:0005829; GO:0005634,Ral GTPase activator activity; activation of Ral GTPase activity; cytosol; nucleus,PF02145;,2.00E-29,CHOYP_LOC100880013.1.1,,,,,,,RGPA1_RAT,Rattus norvegicus (Rat),activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] comp142440_c1_seq1,1425,39.9298,0.25125236,27,276,,6.00E-80,Q5TFE4,5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-),5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF05761;,6.00E-15,CHOYP_LOC100556034.1.2,,,,,,,NT5D1_HUMAN,Homo sapiens (Human), comp142440_c1_seq2,1121,40.8564,0.23734634,16,173,,6.00E-14,Q9H857,5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-),5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF05761;,,,,,,,,,NT5D2_HUMAN,Homo sapiens (Human), comp142442_c1_seq1,2361,43.2867,0.53410381,408,3106,,0,Q8K4L0,ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (DEAD box protein 54),ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (DEAD box protein 54),GO:0005524; GO:0004004; GO:0003723; GO:0006396; GO:0030331; GO:0005730; GO:0006355; GO:0003714; GO:0006351,"ATP binding; ATP-dependent RNA helicase activity; RNA binding; RNA processing; estrogen receptor binding; nucleolus; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF08147;PF00270;PF00271;,6.00E-176,CHOYP_LOC100375838.1.1,,,,,,,DDX54_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]" comp142444_c0_seq2,2207,38.0607,0.81451062,732,1581,,1.00E-48,Q6VFT5,Forkhead box protein L2,Forkhead box protein L2,GO:0003677; GO:0006309; GO:0030154; GO:0043028; GO:0002074; GO:0042703; GO:0005634; GO:0001541; GO:0043065; GO:0043280; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"DNA binding; apoptotic DNA fragmentation; cell differentiation; cysteine-type endopeptidase regulator activity involved in apoptotic process; extraocular skeletal muscle development; menstruation; nucleus; ovarian follicle development; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,1.00E-62,CHOYP_LOC100136214.1.1,,,9.00E-63,AM860211.p.cg.6,4,female gonad,FOXL2_RABIT,Oryctolagus cuniculus (Rabbit),"apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; extraocular skeletal muscle development [GO:0002074]; menstruation [GO:0042703]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription from RNA polymerase II promoter [GO:0006366]" comp142445_c0_seq2,1249,36.8295,0.44917286,1,303,female>male,1.00E-92,Q9WTP7,"GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1)","GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1)",GO:0046033; GO:0005524; GO:0005525; GO:0046039; GO:0046041; GO:0046051; GO:0004017; GO:0005759; GO:0046899,AMP metabolic process; ATP binding; GTP binding; GTP metabolic process; ITP metabolic process; UTP metabolic process; adenylate kinase activity; mitochondrial matrix; nucleoside triphosphate adenylate kinase activity,PF05191;,1.00E-60,CHOYP_BRAFLDRAFT_61507.1.1,,,,,,,KAD3_MOUSE,Mus musculus (Mouse),ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; GTP metabolic process [GO:0046039]; ITP metabolic process [GO:0046041]; UTP metabolic process [GO:0046051] comp142446_c0_seq1,2373,40.3708,0.81028574,1201,4771,,6.00E-07,Q24009,Protein bicaudal C,Protein bicaudal C,GO:0030036; GO:0003729; GO:0000226; GO:0007067; GO:0007275; GO:0007319; GO:0007297,actin cytoskeleton organization; mRNA binding; microtubule cytoskeleton organization; mitosis; multicellular organismal development; negative regulation of oskar mRNA translation; ovarian follicle cell migration,PF00013;PF00536;,,,,,,,,,BICC_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; microtubule cytoskeleton organization [GO:0000226]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]; negative regulation of oskar mRNA translation [GO:0007319]; oogenesis [GO:0048477]; ovarian follicle cell migration [GO:0007297] comp142446_c0_seq2,2557,44.2706,0.55680278,1133,1817,,0,Q8VDJ3,Vigilin (High density lipoprotein-binding protein) (HDL-binding protein),Vigilin (High density lipoprotein-binding protein) (HDL-binding protein),GO:0003723; GO:0008203; GO:0005737; GO:0034364; GO:0006869; GO:0005634,RNA binding; cholesterol metabolic process; cytoplasm; high-density lipoprotein particle; lipid transport; nucleus,PF00013;,0,CHOYP_VIGLN.1.2,,,,,,,VIGLN_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869] comp142447_c0_seq1,1052,39.3536,0.2480626,0,0,,2.00E-72,Q4R8B9,HORMA domain-containing protein 1,HORMA domain-containing protein 1,GO:0001824; GO:0030154; GO:0005694; GO:0042138; GO:0051598; GO:0051177; GO:0005634; GO:0048477; GO:0060629; GO:0007283; GO:0007130,blastocyst development; cell differentiation; chromosome; meiotic DNA double-strand break formation; meiotic recombination checkpoint; meiotic sister chromatid cohesion; nucleus; oogenesis; regulation of homologous chromosome segregation; spermatogenesis; synaptonemal complex assembly,PF02301;,2.00E-58,CHOYP_LOC100378946.1.1,,,,,,,HORM1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),blastocyst development [GO:0001824]; meiotic DNA double-strand break formation [GO:0042138]; meiotic nuclear division [GO:0007126]; meiotic recombination checkpoint [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] comp142447_c0_seq3,3035,36.145,0.3443455,0,0,,1.00E-57,E2QXH7,HORMA domain-containing protein 2,HORMA domain-containing protein 2,GO:0005694; GO:0051177; GO:0005634,chromosome; meiotic sister chromatid cohesion; nucleus,PF02301;,,,,,,,,,HORM2_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),meiotic nuclear division [GO:0007126]; meiotic sister chromatid cohesion [GO:0051177] comp142447_c0_seq4,2985,36.2814,0.32648847,0,0,,,,,,,,,4.00E-58,CHOYP_LOC100378946.1.1,,,,,,,,, comp142447_c0_seq5,1102,38.8385,0.29156778,0,0,,7.00E-72,Q2KIY6,HORMA domain-containing protein 1,HORMA domain-containing protein 1,GO:0001824; GO:0030154; GO:0005694; GO:0045111; GO:0042138; GO:0051598; GO:0051177; GO:0005634; GO:0048477; GO:0060629; GO:0007283; GO:0007130,blastocyst development; cell differentiation; chromosome; intermediate filament cytoskeleton; meiotic DNA double-strand break formation; meiotic recombination checkpoint; meiotic sister chromatid cohesion; nucleus; oogenesis; regulation of homologous chromosome segregation; spermatogenesis; synaptonemal complex assembly,PF02301;,,,,,,,,,HORM1_BOVIN,Bos taurus (Bovine),blastocyst development [GO:0001824]; meiotic DNA double-strand break formation [GO:0042138]; meiotic nuclear division [GO:0007126]; meiotic recombination checkpoint [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] comp142447_c0_seq6,2998,36.2241,0.32637998,0,0,,2.00E-66,Q4R8B9,HORMA domain-containing protein 1,HORMA domain-containing protein 1,GO:0001824; GO:0030154; GO:0005694; GO:0042138; GO:0051598; GO:0051177; GO:0005634; GO:0048477; GO:0060629; GO:0007283; GO:0007130,blastocyst development; cell differentiation; chromosome; meiotic DNA double-strand break formation; meiotic recombination checkpoint; meiotic sister chromatid cohesion; nucleus; oogenesis; regulation of homologous chromosome segregation; spermatogenesis; synaptonemal complex assembly,PF02301;,,,,,,,,,HORM1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),blastocyst development [GO:0001824]; meiotic DNA double-strand break formation [GO:0042138]; meiotic nuclear division [GO:0007126]; meiotic recombination checkpoint [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] comp142448_c0_seq1,2705,40.2588,0.61640519,17,101,,0,O70310,Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1),Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1),GO:0018008; GO:0015629; GO:0030054; GO:0005737; GO:0004379; GO:0001701; GO:0005886,N-terminal peptidyl-glycine N-myristoylation; actin cytoskeleton; cell junction; cytoplasm; glycylpeptide N-tetradecanoyltransferase activity; in utero embryonic development; plasma membrane,PF01233;PF02799;,0,CHOYP_NMT2.1.2,,,,,,,NMT1_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499] comp142448_c0_seq2,2726,40.2788,0.62039279,33,63,,0,Q9N181,Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Type II N-myristoyltransferase),Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Type II N-myristoyltransferase),GO:0006499; GO:0005737; GO:0004379,N-terminal protein myristoylation; cytoplasm; glycylpeptide N-tetradecanoyltransferase activity,PF01233;PF02799;,0,CHOYP_NMT2.1.2,,,,,,,NMT2_BOVIN,Bos taurus (Bovine),N-terminal peptidyl-glycine N-myristoylation [GO:0018008] comp142451_c1_seq2,1323,37.1882,0.3969885,327,973,,,,,,,,,2.00E-13,CHOYP_contig_006180,,,,,,,,, comp142456_c0_seq1,2437,38.572,0.95105228,134,0,,2.00E-24,Q1RGU4,Alanine racemase (EC 5.1.1.1),Alanine racemase (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR_RICBR,Rickettsia bellii (strain RML369-C),D-alanine biosynthetic process [GO:0030632] comp142456_c0_seq2,2393,37.944,1.0459479,243,13,,6.00E-51,Q8RAK6,Alanine racemase 1 (EC 5.1.1.1),Alanine racemase 1 (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR1_THETN,Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis),D-alanine biosynthetic process [GO:0030632] comp142457_c0_seq1,1920,43.2812,0.51224305,74,22,,2.00E-62,Q69YW0,Uncharacterized protein C1orf222,,,,,,,,,,,,,CA222_HUMAN,, comp142457_c0_seq2,1578,41.8885,0.46373851,26,19,,4.00E-63,Q69YW0,Uncharacterized protein C1orf222,,,,,,,,,,,,,CA222_HUMAN,, comp142459_c0_seq5,723,43.1535,0.60942878,6,91,,5.00E-58,Q96PY6,Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55),Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55),GO:0005524; GO:0051301; GO:0042384; GO:0046872; GO:0007067; GO:0031965; GO:0005730; GO:0018108; GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0006974; GO:0010212,ATP binding; cell division; cilium assembly; metal ion binding; mitosis; nuclear membrane; nucleolus; peptidyl-tyrosine phosphorylation; pericentriolar material; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; response to DNA damage stimulus; response to ionizing radiation,PF00069;,2.00E-16,CHOYP_LOC100061302.1.1,,,,,,,NEK1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468] comp142460_c0_seq1,2459,35.9902,0.22641976,5,37,,4.00E-07,P69527,Aminopeptidase O (AP-O) (EC 3.4.11.-),Aminopeptidase O (AP-O) (EC 3.4.11.-),GO:0004177; GO:0005737; GO:0019370; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; leukotriene biosynthetic process; metallopeptidase activity; proteolysis; zinc ion binding,PF09127;PF01433;,,,,,,,,,AMPO_RAT,Rattus norvegicus (Rat),peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp142460_c0_seq2,2574,36.014,0.22781248,29,60,,1.00E-116,Q3SZH7,Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase),Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase),GO:0004177; GO:0005737; GO:0004301; GO:0019370; GO:0004463; GO:0008237; GO:0005634; GO:0043171; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; epoxide hydrolase activity; leukotriene biosynthetic process; leukotriene-A4 hydrolase activity; metallopeptidase activity; nucleus; peptide catabolic process; proteolysis; zinc ion binding,PF09127;PF01433;,2.00E-30,CHOYP_BRAFLDRAFT_215361.1.1,,,,,,,LKHA4_BOVIN,Bos taurus (Bovine),leukotriene biosynthetic process [GO:0019370]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp142460_c0_seq3,293,39.5904,0.35475526,3,0,,2.00E-27,P24527,Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase),Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase),GO:0004177; GO:0005737; GO:0004301; GO:0019370; GO:0004463; GO:0008237; GO:0005634; GO:0043171; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; epoxide hydrolase activity; leukotriene biosynthetic process; leukotriene-A4 hydrolase activity; metallopeptidase activity; nucleus; peptide catabolic process; proteolysis; zinc ion binding,PF09127;PF01433;,,,,,,,,,LKHA4_MOUSE,Mus musculus (Mouse),leukotriene biosynthetic process [GO:0019370]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; response to peptide hormone [GO:0043434]; response to zinc ion [GO:0010043]; Type I pneumocyte differentiation [GO:0060509] comp142461_c0_seq1,2214,39.3406,0.63463694,176,1009,,2.00E-108,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,3.00E-40,CHOYP_HSPA12A.2.27,2.00E-103,ruditapes_c1110,,,,,HS12B_HUMAN,Homo sapiens (Human), comp142461_c0_seq2,583,40.6518,0.5887962,0,6,,,,,,,,,3.00E-20,CHOYP_BRAFLDRAFT_208436.24.32,,,,,,,,, comp142461_c1_seq1,4662,42.5568,0.61264344,0,0,,0,Q7PPA5,Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0033017,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; sarcoplasmic reticulum membrane,PF00689;PF00690;PF00122;PF08282;,,,,,,,,,ATC1_ANOGA,Anopheles gambiae (African malaria mosquito),cellular calcium ion homeostasis [GO:0006874] comp142461_c1_seq10,3933,44.1393,0.6122811,0,0,,0,Q7PPA5,Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0033017,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; sarcoplasmic reticulum membrane,PF00689;PF00690;PF00122;PF08282;,0,CHOYP_ATC1.1.1,,,,,,,ATC1_ANOGA,Anopheles gambiae (African malaria mosquito),cellular calcium ion homeostasis [GO:0006874] comp142461_c1_seq11,1185,37.9747,0.63258377,0,0,,,,,,,,,3.00E-17,CHOYP_CRE-SCA-1.1.1,,,,,,,,, comp142461_c1_seq12,1914,36.4159,0.59952233,0,0,,2.00E-48,P35316,Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0033017,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; sarcoplasmic reticulum membrane,PF00689;PF00690;PF00122;,,,,,,,,,ATC_ARTSF,Artemia franciscana (Brine shrimp) (Artemia sanfranciscana), comp142461_c1_seq2,2204,40.608,0.65015006,0,4,,7.00E-59,O77696,Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment),Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment),GO:0005524; GO:0005388; GO:0005789; GO:0016021; GO:0046872; GO:0031965,ATP binding; calcium-transporting ATPase activity; endoplasmic reticulum membrane; integral to membrane; metal ion binding; nuclear membrane,PF00689;,5.00E-12,CHOYP_ISCW_ISCW009225.1.1,,,,,,,AT2A3_PIG,Sus scrofa (Pig), comp142461_c1_seq3,2187,41.6095,0.64514396,0,0,,7.00E-59,O77696,Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment),Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment),GO:0005524; GO:0005388; GO:0005789; GO:0016021; GO:0046872; GO:0031965,ATP binding; calcium-transporting ATPase activity; endoplasmic reticulum membrane; integral to membrane; metal ion binding; nuclear membrane,PF00689;,,,,,,,,,AT2A3_PIG,Sus scrofa (Pig), comp142461_c1_seq4,4091,43.5346,0.62044657,0,0,,0,P35316,Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0033017,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; sarcoplasmic reticulum membrane,PF00689;PF00690;PF00122;,0,CHOYP_ATC1.1.1,,,,,,,ATC_ARTSF,Artemia franciscana (Brine shrimp) (Artemia sanfranciscana), comp142461_c1_seq5,4108,43.0623,0.63145928,0,0,,0,Q7PPA5,Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump),GO:0005524; GO:0005388; GO:0016021; GO:0046872; GO:0033017,ATP binding; calcium-transporting ATPase activity; integral to membrane; metal ion binding; sarcoplasmic reticulum membrane,PF00689;PF00690;PF00122;PF08282;,0,CHOYP_ATC1.1.1,,,,,,,ATC1_ANOGA,Anopheles gambiae (African malaria mosquito),cellular calcium ion homeostasis [GO:0006874] comp142461_c1_seq6,2758,40.3191,0.61661428,0,0,,1.00E-28,Q9LV11,"ATPase 11, plasma membrane-type (EC 3.6.3.6) (Proton pump 11)","ATPase 11, plasma membrane-type (EC 3.6.3.6) (Proton pump 11)",GO:0005524; GO:0006754; GO:0008553; GO:0016021; GO:0046872; GO:0005886,"ATP binding; ATP biosynthetic process; hydrogen-exporting ATPase activity, phosphorylative mechanism; integral to membrane; metal ion binding; plasma membrane",PF00690;PF00122;,,,,,,,,,PMA11_ARATH,Arabidopsis thaliana (Mouse-ear cress),ATP biosynthetic process [GO:0006754]; hydrogen ion transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453] comp142461_c1_seq8,2029,42.6318,0.63014476,1,0,,4.00E-59,O77696,Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment),Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment),GO:0005524; GO:0005388; GO:0005789; GO:0016021; GO:0046872; GO:0031965,ATP binding; calcium-transporting ATPase activity; endoplasmic reticulum membrane; integral to membrane; metal ion binding; nuclear membrane,PF00689;,5.00E-17,CHOYP_CRE-SCA-1.1.1,,,,,,,AT2A3_PIG,Sus scrofa (Pig), comp142461_c1_seq9,1343,36.8578,0.6582216,0,0,,,,,,,,,,,7.00E-56,ruditapes_c21314,,,,,,, comp142462_c0_seq1,2180,36.9725,0.49688752,5099,187,,0,Q9JLI7,Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog),Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog),GO:0030030; GO:0005929; GO:0005737; GO:0005874; GO:0030317; GO:0007283,cell projection organization; cilium; cytoplasm; microtubule; sperm motility; spermatogenesis,PF00514;PF02985;,0,CHOYP_LOC589479.1.2,,,9.00E-138,CU990254.p.cg.6,5,,SPAG6_MOUSE,Mus musculus (Mouse),sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]; ventricular system development [GO:0021591] comp142462_c1_seq1,619,45.2342,0.50739225,577,19,,8.00E-06,O35344,Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3),Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3),GO:0005737; GO:0005634; GO:0006606; GO:0008565,cytoplasm; nucleus; protein import into nucleus; protein transporter activity,PF00514;PF16186;PF01749;,,,,,2.00E-93,AM860311.p.cg.6,5,,IMA3_MOUSE,Mus musculus (Mouse),NLS-bearing protein import into nucleus [GO:0006607] comp142463_c0_seq1,4703,40.4423,0.67401162,9,71,,0,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp142463_c0_seq10,4354,41.525,0.71169578,0,0,,0,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,0,CHOYP_MVP.1.1,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp142463_c0_seq11,4703,40.74,0.67474094,0,0,,0,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp142463_c0_seq2,4303,41.4827,0.71652276,4,22,,,,,,,,,0,CHOYP_MVP.1.1,,,,,,,,, comp142463_c0_seq4,4665,40.6645,0.6725597,0,0,,0,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,0,CHOYP_MVP.1.1,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp142463_c0_seq5,4316,41.4504,0.72066683,0,172,,0,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp142463_c0_seq6,4716,40.4792,0.67587142,0,0,,,,,,,,,0,CHOYP_MVP.1.1,,,,,,,,, comp142463_c0_seq7,4678,40.637,0.6765863,0,0,,0,Q6P3L0,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),brain development [GO:0007420]; eye development [GO:0001654]; neuron projection regeneration [GO:0031102] comp142463_c0_seq9,4341,41.5342,0.70831803,0,0,,,,,,,,,0,CHOYP_MVP.1.1,,,,,,,,, comp142465_c0_seq1,3794,46.389,0.57732336,24,128,,,,,,,,,0,CHOYP_CTR9.1.1,,,,,,,,, comp142465_c0_seq2,3826,46.1056,0.57484758,0,0,,0,Q6PD62,RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1),RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1),GO:0016593; GO:0007259; GO:0016055; GO:0071222; GO:0001711; GO:0033523; GO:0080182; GO:0010390; GO:0070102; GO:0045638; GO:0000122; GO:0016607; GO:0051571; GO:2001162; GO:0032968; GO:0045944; GO:0019827; GO:0006351; GO:0035327,"Cdc73/Paf1 complex; JAK-STAT cascade; Wnt receptor signaling pathway; cellular response to lipopolysaccharide; endodermal cell fate commitment; histone H2B ubiquitination; histone H3-K4 trimethylation; histone monoubiquitination; interleukin-6-mediated signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; nuclear speck; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K79 methylation; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance; transcription, DNA-dependent; transcriptionally active chromatin",PF13181;,,,,,,,,,CTR9_HUMAN,Homo sapiens (Human),"blastocyst growth [GO:0001832]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone H3-K4 trimethylation [GO:0080182]; histone monoubiquitination [GO:0010390]; inner cell mass cell differentiation [GO:0001826]; interleukin-6-mediated signaling pathway [GO:0070102]; JAK-STAT cascade [GO:0007259]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of genetic imprinting [GO:2000653]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]; Wnt signaling pathway [GO:0016055]" comp142465_c0_seq4,3817,46.2405,0.58221705,21,79,,0,Q6PD62,RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1),RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1),GO:0016593; GO:0007259; GO:0016055; GO:0071222; GO:0001711; GO:0033523; GO:0080182; GO:0010390; GO:0070102; GO:0045638; GO:0000122; GO:0016607; GO:0051571; GO:2001162; GO:0032968; GO:0045944; GO:0019827; GO:0006351; GO:0035327,"Cdc73/Paf1 complex; JAK-STAT cascade; Wnt receptor signaling pathway; cellular response to lipopolysaccharide; endodermal cell fate commitment; histone H2B ubiquitination; histone H3-K4 trimethylation; histone monoubiquitination; interleukin-6-mediated signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; nuclear speck; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K79 methylation; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance; transcription, DNA-dependent; transcriptionally active chromatin",PF13181;,0,CHOYP_CTR9.1.1,1.00E-33,ruditapes_c10824,,,,,CTR9_HUMAN,Homo sapiens (Human),"blastocyst growth [GO:0001832]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone H3-K4 trimethylation [GO:0080182]; histone monoubiquitination [GO:0010390]; inner cell mass cell differentiation [GO:0001826]; interleukin-6-mediated signaling pathway [GO:0070102]; JAK-STAT cascade [GO:0007259]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of genetic imprinting [GO:2000653]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]; Wnt signaling pathway [GO:0016055]" comp142471_c0_seq1,3387,42.1022,0.40711531,0,0,,,,,,,,,1.00E-21,CHOYP_LOC100890653.1.1,,,,,,,,, comp142471_c0_seq2,3391,42.082,0.44027521,0,0,,6.00E-06,A1A5X2,F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7),F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7),GO:0005737; GO:0005815; GO:0016567,cytoplasm; microtubule organizing center; protein ubiquitination,PF12937;PF13516;,,,,,,,,,FBXL7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp142471_c0_seq3,3367,41.9661,0.4256518,0,0,,1.00E-08,Q6GLV4,UBX domain-containing protein 1-B (SAPK substrate protein 1-B),UBX domain-containing protein 1-B (SAPK substrate protein 1-B),GO:0005737,cytoplasm,PF00627;PF00789;,,,,,,,,,UBX1B_XENLA,Xenopus laevis (African clawed frog), comp142471_c0_seq4,3360,41.9643,0.3927035,1,0,,2.00E-06,Q9ZWC6,F-box protein At-B,F-box protein At-B,,,PF00646;PF13516;,1.00E-21,CHOYP_LOC100890653.1.1,,,,,,,ATB_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp142471_c0_seq6,3394,42.0153,0.42137774,0,0,,1.00E-08,Q6GLV4,UBX domain-containing protein 1-B (SAPK substrate protein 1-B),UBX domain-containing protein 1-B (SAPK substrate protein 1-B),GO:0005737,cytoplasm,PF00627;PF00789;,1.00E-21,CHOYP_LOC100890653.1.1,,,,,,,UBX1B_XENLA,Xenopus laevis (African clawed frog), comp142472_c0_seq1,3393,46.0654,0.30587602,0,0,,3.00E-37,Q9W1R5,Protein virilizer,Protein virilizer,GO:0000375; GO:0007298; GO:0007549; GO:0016021; GO:0006397; GO:0003676; GO:0005634; GO:0007539; GO:0000381,"RNA splicing, via transesterification reactions; border follicle cell migration; dosage compensation; integral to membrane; mRNA processing; nucleic acid binding; nucleus; primary sex determination, soma; regulation of alternative mRNA splicing, via spliceosome",PF15912;,1.00E-14,CHOYP_VIR.1.1,,,,,,,VIR_DROME,Drosophila melanogaster (Fruit fly),"border follicle cell migration [GO:0007298]; dosage compensation [GO:0007549]; mRNA processing [GO:0006397]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing, via transesterification reactions [GO:0000375]; sex determination [GO:0007530]" comp142472_c0_seq2,2084,44.8177,0.52046701,9,27,,,,,,,,,,,1.00E-49,ruditapes_c14643,,,,,,, comp142472_c0_seq4,3394,45.9635,0.30733643,11,43,,2.00E-110,Q69YN4,Protein virilizer homolog,Protein virilizer homolog,GO:0008380; GO:0006397; GO:0005634,RNA splicing; mRNA processing; nucleus,PF15912;,1.00E-14,CHOYP_VIR.1.1,,,,,,,VIR_HUMAN,Homo sapiens (Human),mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp142475_c0_seq1,2086,37.0086,0.49199497,311,417,,5.00E-27,Q9H892,Tetratricopeptide repeat protein 12 (TPR repeat protein 12),Tetratricopeptide repeat protein 12 (TPR repeat protein 12),,,PF00515;PF13181;,4.00E-25,CHOYP_TTC12.1.1,,,,,,,TTC12_HUMAN,Homo sapiens (Human), comp142475_c0_seq3,909,42.7943,0.44542394,48,45,,1.00E-52,Q95LY5,Tetratricopeptide repeat protein 12 (TPR repeat protein 12) (Fragment),Tetratricopeptide repeat protein 12 (TPR repeat protein 12) (Fragment),,,PF00515;PF13181;,,,,,,,,,TTC12_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp142476_c0_seq1,1385,36.9675,0.72038561,7,48,,4.00E-53,Q54LT8,Serine-threonine kinase receptor-associated protein (WD40 repeat-containing protein strap),Serine-threonine kinase receptor-associated protein (WD40 repeat-containing protein strap),GO:0030512,negative regulation of transforming growth factor beta receptor signaling pathway,PF08662;PF00400;,,,,,,,,,STRAP_DICDI,Dictyostelium discoideum (Slime mold),negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] comp142476_c0_seq2,1443,36.4518,0.71181511,0,0,,8.00E-94,Q5ZL33,Serine-threonine kinase receptor-associated protein,Serine-threonine kinase receptor-associated protein,GO:0008380; GO:0030054; GO:0006397; GO:0005739; GO:0000122; GO:0030512; GO:0005886; GO:0005102; GO:0005681,RNA splicing; cell junction; mRNA processing; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; plasma membrane; receptor binding; spliceosomal complex,PF00400;,,,,,,,,,STRAP_CHICK,Gallus gallus (Chicken),maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; spliceosomal snRNP assembly [GO:0000387] comp142476_c0_seq3,1440,36.9444,0.69291617,0,0,,6.00E-10,B7PS00,Lissencephaly-1 homolog,Lissencephaly-1 homolog,GO:0051301; GO:0006928; GO:0005737; GO:0000132; GO:0005874; GO:0005875; GO:0005815; GO:0007067; GO:0006810,cell division; cellular component movement; cytoplasm; establishment of mitotic spindle orientation; microtubule; microtubule associated complex; microtubule organizing center; mitosis; transport,PF08513;PF00400;,,,,,,,,,LIS1_IXOSC,Ixodes scapularis (Black-legged tick) (Deer tick),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; neurogenesis [GO:0022008]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496] comp142476_c0_seq4,308,45.7792,0.50305781,23,73,,2.00E-09,P79083,Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 39 kDa subunit homolog) (eIF-3 39 kDa subunit homolog) (eIF3 p39) (Suppressor of uncontrolled mitosis 1),Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 39 kDa subunit homolog) (eIF-3 39 kDa subunit homolog) (eIF3 p39) (Suppressor of uncontrolled mitosis 1),GO:0071470; GO:0002183; GO:0005829; GO:0016282; GO:0033290; GO:0071540; GO:0071541; GO:0001731; GO:0034399; GO:0006446; GO:0003743,"cellular response to osmotic stress; cytoplasmic translational initiation; cytosol; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 complex, eIF3m; formation of translation preinitiation complex; nuclear periphery; regulation of translational initiation; translation initiation factor activity",PF00400;,8.00E-56,CHOYP_LOC100118098.1.1,,,,,,,EIF3I_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular response to osmotic stress [GO:0071470]; cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] comp142476_c0_seq5,1302,37.4808,0.72370656,0,0,,1.00E-17,Q9VU65,POC1 centriolar protein homolog (Proteome of centrioles 1),POC1 centriolar protein homolog (Proteome of centrioles 1),GO:0051297,centrosome organization,PF12894;PF00400;,,,,,,,,,POC1_DROME,Drosophila melanogaster (Fruit fly),centrosome organization [GO:0051297] comp142476_c0_seq6,1382,37.699,0.71374894,0,8,,2.00E-13,Q9C270,Periodic tryptophan protein 2 homolog,Periodic tryptophan protein 2 homolog,,,PF04003;PF00400;,,,,,,,,,PWP2_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]" comp142476_c0_seq7,1299,38.0293,0.7247807,0,0,,8.00E-16,Q10051,Pre-mRNA-processing factor 19 homolog (PRP19/PSO4 homolog),Pre-mRNA-processing factor 19 (EC 6.3.2.-) (PRP19/PSO4 homolog),GO:0003677; GO:0006281; GO:0008380; GO:0030154; GO:0006397; GO:0007275; GO:0005654; GO:0005681; GO:0000151; GO:0004842,DNA binding; DNA repair; RNA splicing; cell differentiation; mRNA processing; multicellular organismal development; nucleoplasm; spliceosomal complex; ubiquitin ligase complex; ubiquitin-protein ligase activity,PF08606;PF04564;PF00400;,,,3.00E-47,ruditapes_c7785,,,,,PRP19_CAEEL,Caenorhabditis elegans,cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; protein K63-linked ubiquitination [GO:0070534]; RNA splicing [GO:0008380] comp142477_c0_seq2,5433,42.0946,0.36902657,7,17,,4.00E-37,P70399,Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1),Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1),GO:0006281; GO:0000777; GO:0003684; GO:0000776; GO:0035064; GO:0005634; GO:0006355; GO:0005657; GO:0042162; GO:0008134; GO:0006351,"DNA repair; condensed chromosome kinetochore; damaged DNA binding; kinetochore; methylated histone residue binding; nucleus; regulation of transcription, DNA-dependent; replication fork; telomeric DNA binding; transcription factor binding; transcription, DNA-dependent",PF09038;,,,,,,,,,TP53B_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142477_c0_seq8,5410,42.0887,0.37098432,0,0,,6.00E-37,P70399,Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1),Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1),GO:0006281; GO:0000777; GO:0003684; GO:0000776; GO:0035064; GO:0005634; GO:0006355; GO:0005657; GO:0042162; GO:0008134; GO:0006351,"DNA repair; condensed chromosome kinetochore; damaged DNA binding; kinetochore; methylated histone residue binding; nucleus; regulation of transcription, DNA-dependent; replication fork; telomeric DNA binding; transcription factor binding; transcription, DNA-dependent",PF09038;,,,,,,,,,TP53B_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142482_c1_seq4,2335,41.4989,0.54025984,0,28,,3.00E-102,Q6NYV9,RNA polymerase-associated protein LEO1,RNA polymerase-associated protein LEO1,GO:0016593; GO:0048701; GO:0021782; GO:0007507; GO:0030318; GO:0014032; GO:0032968; GO:0045944; GO:0021529; GO:0006351; GO:0050936,"Cdc73/Paf1 complex; embryonic cranial skeleton morphogenesis; glial cell development; heart development; melanocyte differentiation; neural crest cell development; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; spinal cord oligodendrocyte cell differentiation; transcription, DNA-dependent; xanthophore differentiation",PF04004;,,,,,,,,,LEO1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic cranial skeleton morphogenesis [GO:0048701]; glial cell development [GO:0021782]; heart development [GO:0007507]; histone modification [GO:0016570]; melanocyte differentiation [GO:0030318]; neural crest cell development [GO:0014032]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; transcription elongation from RNA polymerase II promoter [GO:0006368]; xanthophore differentiation [GO:0050936] comp142482_c1_seq5,2452,41.3132,0.52066657,11,75,,7.00E-102,Q6NYV9,RNA polymerase-associated protein LEO1,RNA polymerase-associated protein LEO1,GO:0016593; GO:0048701; GO:0021782; GO:0007507; GO:0030318; GO:0014032; GO:0032968; GO:0045944; GO:0021529; GO:0006351; GO:0050936,"Cdc73/Paf1 complex; embryonic cranial skeleton morphogenesis; glial cell development; heart development; melanocyte differentiation; neural crest cell development; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; spinal cord oligodendrocyte cell differentiation; transcription, DNA-dependent; xanthophore differentiation",PF04004;,2.00E-105,CHOYP_LEO1.1.1,,,,,,,LEO1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic cranial skeleton morphogenesis [GO:0048701]; glial cell development [GO:0021782]; heart development [GO:0007507]; histone modification [GO:0016570]; melanocyte differentiation [GO:0030318]; neural crest cell development [GO:0014032]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; transcription elongation from RNA polymerase II promoter [GO:0006368]; xanthophore differentiation [GO:0050936] comp142483_c1_seq4,1498,47.6636,0.51913852,23,0,,6.00E-22,Q60722,Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2),Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2),GO:0070888; GO:0000978; GO:0001077; GO:0001087; GO:0001093; GO:0000122; GO:0005634; GO:0045666; GO:0046982; GO:0065004; GO:0001011; GO:0003714; GO:0005667; GO:0006367,E-box binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; TFIIB-class binding transcription factor activity; TFIIB-class transcription factor binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of neuron differentiation; protein heterodimerization activity; protein-DNA complex assembly; sequence-specific DNA binding RNA polymerase recruiting transcription factor activity; transcription corepressor activity; transcription factor complex; transcription initiation from RNA polymerase II promoter,PF00010;,1.00E-23,CHOYP_ITF2.1.1,,,,,,,ITF2_MOUSE,Mus musculus (Mouse),"DNA-templated transcription, initiation [GO:0006352]; endothelial cell activation [GO:0042118]; negative regulation of angiogenesis [GO:0016525]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein-DNA complex assembly [GO:0065004]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp142483_c1_seq5,1427,47.7225,0.79559281,0,0,,,,,,,,,1.00E-23,CHOYP_HTF4.5.5,,,,,,,,, comp142483_c1_seq6,2732,43.1552,0.67449401,119,179,,2.00E-33,Q90683,Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) (Fragment),Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) (Fragment),GO:0070888; GO:0005634; GO:0045666; GO:0046982; GO:0006355; GO:0006351,"E-box binding; nucleus; positive regulation of neuron differentiation; protein heterodimerization activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00010;,2.00E-24,CHOYP_HTF4.3.5,,,,,,,ITF2_CHICK,Gallus gallus (Chicken),"positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp142483_c1_seq7,859,50.0582,0.66409356,0,0,,7.00E-06,Q01978,Transcription factor E2-alpha (Transcription factor 3) (TCF-3) (Transcription factor XE12/XE47),Transcription factor E2-alpha (Transcription factor 3) (TCF-3) (Transcription factor XE12/XE47),GO:0003677; GO:0005634; GO:0045666; GO:0046982; GO:0003700; GO:0006351,"DNA binding; nucleus; positive regulation of neuron differentiation; protein heterodimerization activity; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00010;,,,,,,,,,TFE2_XENLA,Xenopus laevis (African clawed frog),"positive regulation of neuron differentiation [GO:0045666]; transcription, DNA-templated [GO:0006351]" comp142484_c0_seq4,1114,36.8941,0.39802507,7,28,,4.00E-54,Q3SZ21,Ribonuclease P protein subunit p30 (RNaseP protein p30) (EC 3.1.26.5) (RNase P subunit 2),Ribonuclease P protein subunit p30 (RNaseP protein p30) (EC 3.1.26.5) (RNase P subunit 2),GO:0005730; GO:0004526; GO:0008033,nucleolus; ribonuclease P activity; tRNA processing,PF01876;,,,,,,,,,RPP30_BOVIN,Bos taurus (Bovine),"RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA processing [GO:0008033]" comp142485_c0_seq1,1489,44.5265,0.55976055,1024,226,,2.00E-76,Q96LI9,Putative uncharacterized protein CXorf58,Putative uncharacterized protein CXorf58,,,,5.00E-104,CHOYP_LOC100377974.1.1,2.00E-89,ruditapes_c12147,,,,,CX058_HUMAN,Homo sapiens (Human), comp142486_c0_seq1,1803,39.1015,0.6140731,700,2978,,2.00E-109,Q8IVS2,"Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase)","Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase)",GO:0004314; GO:0006633; GO:0005739,[acyl-carrier-protein] S-malonyltransferase activity; fatty acid biosynthetic process; mitochondrion,PF00698;,,,1.00E-15,ruditapes_c9210,,,,,FABD_HUMAN,Homo sapiens (Human),fatty acid biosynthetic process [GO:0006633]; metabolic process [GO:0008152] comp142488_c0_seq1,667,46.3268,0.50385631,18,68,,,,,,,,,6.00E-36,CHOYP_RA54B.1.1,,,,,,,,, comp142488_c1_seq1,2279,41.4656,0.50042563,105,748,,0,Q8BWQ6,UPF0505 protein C16orf62 homolog,UPF0505 protein C16orf62 homolog,GO:0016021,integral to membrane,,6.00E-169,CHOYP_LOC594407.1.1,,,,,,,CP062_MOUSE,Mus musculus (Mouse),Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] comp142489_c0_seq1,5785,36.3354,0.64888986,14116,902557,,2.00E-94,P51899,NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5) (Fragment),NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5) (Fragment),GO:0042773; GO:0008137; GO:0016021; GO:0005743; GO:0070469,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; integral to membrane; mitochondrial inner membrane; respiratory chain,PF00361;PF00662;,,,5.00E-46,ruditapes_c60,,,,,NU5M_ANOAR,Anopheles arabiensis (Mosquito), comp142495_c0_seq1,1936,39.3595,0.50346338,29,262,,5.00E-13,Q01277,Probable E3 ubiquitin ligase complex SCF subunit scon-2 (Sulfur controller 2) (SCON2) (Sulfur metabolite repression control protein 2),Probable E3 ubiquitin ligase complex SCF subunit scon-2 (Sulfur controller 2) (SCON2) (Sulfur metabolite repression control protein 2),GO:0016567; GO:0006355; GO:0006351,"protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12937;PF00400;,,,,,,,,,SCONB_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142495_c0_seq2,1766,39.2412,0.41209459,19,135,,6.00E-10,P87060,WD repeat-containing protein pop1 (WD repeat-containing protein ste16),WD repeat-containing protein pop1 (WD repeat-containing protein ste16),GO:0019005; GO:0006995; GO:0000747; GO:0008054; GO:0005634; GO:0007346,SCF ubiquitin ligase complex; cellular response to nitrogen starvation; conjugation with cellular fusion; cyclin catabolic process; nucleus; regulation of mitotic cell cycle,PF12937;PF00400;,,,,,,,,,POP1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),conjugation with cellular fusion [GO:0000747]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; regulation of mitotic cell cycle [GO:0007346]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142496_c0_seq1,1122,37.6114,0.83607511,75,366,,6.00E-06,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp142496_c0_seq3,1003,37.986,0.7791582,82,167,,8.00E-06,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp142497_c0_seq1,471,46.7091,0.74171205,13,65,,,,,,,,,6.00E-47,CHOYP_CHER.1.1,,,,,,,,, comp142497_c1_seq4,884,40.6109,0.831039,32,226,,8.00E-38,Q9MZD2,Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin) (C254) (Fragment),Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin) (C254) (Fragment),GO:0005938; GO:0005856,cell cortex; cytoskeleton,PF00630;,,,3.00E-46,ruditapes2_c2712,,,,,FLNB_RABIT,Oryctolagus cuniculus (Rabbit),actin cytoskeleton organization [GO:0030036]; cell differentiation [GO:0030154] comp142499_c0_seq3,2000,47.45,0.29720504,3,0,,1.00E-19,Q9BY77,Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR),Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR),GO:0003723; GO:0005737; GO:0016607; GO:0000166; GO:0045727,RNA binding; cytoplasm; nuclear speck; nucleotide binding; positive regulation of translation,PF00076;,,,,,,,,,PDIP3_HUMAN,Homo sapiens (Human),mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of translation [GO:0045727]; RNA export from nucleus [GO:0006405]; termination of RNA polymerase II transcription [GO:0006369] comp142500_c0_seq4,1144,37.3252,0.57942839,1,51,,,,,,,,,,,1.00E-13,ruditapes_c18530,,,,,,, comp142503_c1_seq3,1691,39.385,0.37129704,564,451,,2.00E-27,Q28298,Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp),Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp),GO:0030176; GO:0015031; GO:0007165,integral to endoplasmic reticulum membrane; protein transport; signal transduction,PF05104;,7.00E-15,CHOYP_LOC100369294.4.6,6.00E-45,ruditapes_c14863,,,,,RRBP1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),protein transport [GO:0015031]; signal transduction [GO:0007165]; translation [GO:0006412] comp142503_c1_seq6,1246,31.6212,0.2916203,163,410,,,,,,,,,,,1.00E-13,ruditapes2_c3057,,,,,,, comp142503_c1_seq9,969,41.0733,0.45850889,11,30,,7.00E-17,Q90631,Kinectin,Kinectin,GO:0005789; GO:0016021; GO:0007018,endoplasmic reticulum membrane; integral to membrane; microtubule-based movement,,1.00E-20,CHOYP_LOC100369294.6.6,1.00E-18,ruditapes_c17970,,,,,KTN1_CHICK,Gallus gallus (Chicken),microtubule-based movement [GO:0007018] comp142505_c0_seq11,2707,46.3613,0.43350466,0,0,,,,,,,,,0,CHOYP_BCAS3.1.1,,,,,,,,, comp142505_c0_seq13,1835,48.0109,0.42579301,0,0,,4.00E-107,Q8CCN5,Breast carcinoma-amplified sequence 3 homolog (K20D4),Breast carcinoma-amplified sequence 3 homolog (K20D4) (Protein rudhira),GO:0071944; GO:0005737; GO:0005634,cell periphery; cytoplasm; nucleus,PF12490;,,,,,,,,,BCAS3_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]" comp142505_c0_seq2,1314,48.0213,0.43613967,0,0,,,,,,,,,3.00E-82,CHOYP_BCAS3.1.1,,,,,,,,, comp142505_c0_seq4,2186,45.9744,0.44179377,0,0,,2.00E-176,Q9H6U6,Breast carcinoma-amplified sequence 3 (GAOB1),Breast carcinoma-amplified sequence 3 (GAOB1),GO:0071944; GO:0005737; GO:0005634,cell periphery; cytoplasm; nucleus,PF12490;,4.00E-158,CHOYP_BCAS3.1.1,,,,,,,BCAS3_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]" comp142505_c0_seq6,5489,38.568,0.3768189,0,0,,1.00E-100,Q8CCN5,Breast carcinoma-amplified sequence 3 homolog (K20D4),Breast carcinoma-amplified sequence 3 homolog (K20D4) (Protein rudhira),GO:0071944; GO:0005737; GO:0005634,cell periphery; cytoplasm; nucleus,PF12490;,,,,,,,,,BCAS3_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]" comp142505_c0_seq9,6361,39.1762,0.38904101,0,0,,0,Q8CCN5,Breast carcinoma-amplified sequence 3 homolog (K20D4),Breast carcinoma-amplified sequence 3 homolog (K20D4) (Protein rudhira),GO:0071944; GO:0005737; GO:0005634,cell periphery; cytoplasm; nucleus,PF12490;,0,CHOYP_BCAS3.1.1,,,,,,,BCAS3_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]" comp142509_c1_seq2,1820,44.1209,0.39904219,85,264,,7.00E-125,Q9Z160,Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein),Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein),GO:0000139; GO:0015031,Golgi membrane; protein transport,,7.00E-110,CHOYP_LOC590969.1.1,,,,,,,COG1_MOUSE,Mus musculus (Mouse),"Golgi organization [GO:0007030]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]" comp142509_c1_seq4,845,44.6154,0.46454027,0,0,,1.00E-51,Q9Z160,Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein),Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein),GO:0000139; GO:0015031,Golgi membrane; protein transport,,,,,,,,,,COG1_MOUSE,Mus musculus (Mouse),"Golgi organization [GO:0007030]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]" comp142510_c1_seq1,1795,42.0056,0.41451747,389,2018,,3.00E-122,O13066,Ran GTPase-activating protein 1 (RanGAP1),Ran GTPase-activating protein 1 (RanGAP1),GO:0005098; GO:0005737; GO:0032853; GO:0007165,Ran GTPase activator activity; cytoplasm; positive regulation of Ran GTPase activity; signal transduction,PF13516;PF07834;,4.00E-88,CHOYP_RAGP1.1.1,,,,,,,RAGP1_XENLA,Xenopus laevis (African clawed frog),signal transduction [GO:0007165] comp142511_c1_seq2,1597,38.3845,0.40827814,4,0,,4.00E-09,Q5U3G4,RAD52 motif-containing protein 1,RAD52 motif-containing protein 1,GO:0003677; GO:0003723; GO:0005737; GO:0005730; GO:0000166,DNA binding; RNA binding; cytoplasm; nucleolus; nucleotide binding,,,,,,,,,,RDM1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142511_c1_seq3,1708,38.1733,0.41810412,0,6,,4.00E-07,Q8JFQ4,RAD52 motif-containing protein 1,RAD52 motif-containing protein 1,GO:0003677; GO:0006310; GO:0006281; GO:0003723; GO:0005737; GO:0005730; GO:0000166,DNA binding; DNA recombination; DNA repair; RNA binding; cytoplasm; nucleolus; nucleotide binding,PF04098;PF00076;,,,,,,,,,RDM1_CHICK,Gallus gallus (Chicken),DNA recombination [GO:0006310]; DNA repair [GO:0006281] comp142511_c1_seq4,2122,35.344,0.49579285,412,45,,,,,,,,,6.00E-143,CHOYP_WDR52.1.1,,,,,,,,, comp142515_c0_seq1,1723,30.8764,0.51271756,38,307,,,,,,,,,,,5.00E-27,ruditapes2_c3232,,,,,,, comp142515_c0_seq2,5369,38.8527,0.52465914,3714,10670,,0,P18091,"Alpha-actinin, sarcomeric (F-actin cross-linking protein)","Alpha-actinin, sarcomeric (F-actin cross-linking protein)",GO:0030018; GO:0003779; GO:0031532; GO:0005509; GO:0007016; GO:0007629; GO:0005925; GO:0045214,Z disc; actin binding; actin cytoskeleton reorganization; calcium ion binding; cytoskeletal anchoring at plasma membrane; flight behavior; focal adhesion; sarcomere organization,PF00307;PF13405;PF08726;PF00435;,0,CHOYP_ACTN.1.2,0,ruditapes_c13583,0,CU683354.p.cg.6,1,,ACTN_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; cytoskeletal anchoring at plasma membrane [GO:0007016]; flight behavior [GO:0007629]; sarcomere organization [GO:0045214] comp142516_c0_seq3,2764,30.644,0.38541962,0,0,,,,,,,,,,,7.00E-15,ruditapes2_c497,,,,,,, comp142517_c1_seq2,3288,40.1764,0.43774127,515,914,,8.00E-27,A6NNF4,Zinc finger protein 726,Zinc finger protein 726,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,0,CHOYP_GZF1.1.2,,,,,,,ZN726_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142519_c0_seq2,4754,45.5616,0.62662362,17,59,,9.00E-112,Q8CEE6,PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1),PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0045719; GO:0005634; GO:0035091; GO:0046777; GO:0004674; GO:2000505; GO:0070092; GO:0043576; GO:0004871,ATP binding; cytoplasm; negative regulation of glycogen biosynthetic process; nucleus; phosphatidylinositol binding; protein autophosphorylation; protein serine/threonine kinase activity; regulation of energy homeostasis; regulation of glucagon secretion; regulation of respiratory gaseous exchange; signal transducer activity,PF13426;PF00069;,1.00E-92,CHOYP_LOC100375061.1.1,,,,,,,PASK_MOUSE,Mus musculus (Mouse),negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of energy homeostasis [GO:2000505]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] comp142519_c0_seq3,3115,45.4575,0.71295912,7,0,,2.00E-24,B4MXR8,Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK),Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK),GO:0005524; GO:0005814; GO:0018108; GO:0004674; GO:0004713,ATP binding; centriole; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;,8.00E-93,CHOYP_LOC100375061.1.1,,,,,,,PLK4_DROWI,Drosophila willistoni (Fruit fly), comp142519_c0_seq4,4218,45.4718,0.65994496,0,0,,2.00E-112,Q8CEE6,PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1),PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0045719; GO:0005634; GO:0035091; GO:0046777; GO:0004674; GO:2000505; GO:0070092; GO:0043576; GO:0004871,ATP binding; cytoplasm; negative regulation of glycogen biosynthetic process; nucleus; phosphatidylinositol binding; protein autophosphorylation; protein serine/threonine kinase activity; regulation of energy homeostasis; regulation of glucagon secretion; regulation of respiratory gaseous exchange; signal transducer activity,PF13426;PF00069;,,,,,,,,,PASK_MOUSE,Mus musculus (Mouse),negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of energy homeostasis [GO:2000505]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] comp142520_c0_seq1,1754,42.8734,1.1493782,212,896,,9.00E-50,Q9UBQ7,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0034641; GO:0007588; GO:0008465; GO:0046487; GO:0030267; GO:0016618; GO:0005782; GO:0042803; GO:0051259,NAD binding; NADPH binding; cellular nitrogen compound metabolic process; excretion; glycerate dehydrogenase activity; glyoxylate metabolic process; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; peroxisomal matrix; protein homodimerization activity; protein oligomerization,PF00389;PF02826;,,,,,,,,,GRHPR_HUMAN,Homo sapiens (Human),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp142521_c0_seq2,2133,36.662,0.57446584,262,840,,6.00E-49,Q9UHR5,SAP30-binding protein (Transcriptional regulator protein HCNGP),SAP30-binding protein (Transcriptional regulator protein HCNGP),GO:0006915; GO:0045111; GO:0005634; GO:0010942; GO:0006355; GO:0006351,"apoptotic process; intermediate filament cytoskeleton; nucleus; positive regulation of cell death; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07818;,1.00E-44,CHOYP_S30BP.1.1,2.00E-76,ruditapes_c8894,,,,,S30BP_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; positive regulation of cell death [GO:0010942]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142522_c0_seq1,2031,46.0857,0.47013542,27,4,,2.00E-104,Q5BKR2,Mitochondrial sodium/hydrogen exchanger 9B2 (Mitochondrial Na(+)/H(+) exchanger NHA2) (NHA-oc) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Sodium/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2),Mitochondrial sodium/hydrogen exchanger 9B2 (Mitochondrial Na(+)/H(+) exchanger NHA2) (NHA-oc) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Sodium/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2),GO:0016021; GO:0031966; GO:0006814; GO:0015299,integral to membrane; mitochondrial membrane; sodium ion transport; solute:hydrogen antiporter activity,PF00999;,1.00E-68,CHOYP_LOC594676.1.1,,,,,,,SL9B2_MOUSE,Mus musculus (Mouse),positive regulation of osteoclast development [GO:2001206]; sodium ion transport [GO:0006814] comp142523_c0_seq6,1009,46.2834,0.43501915,522,685,,2.00E-63,Q5ZLF0,Hsc70-interacting protein (Hip) (Protein FAM10A1) (Protein ST13 homolog),Hsc70-interacting protein (Hip) (Protein FAM10A1) (Protein ST13 homolog),GO:0005737,cytoplasm,,3.00E-29,CHOYP_F10A1.4.4,,,,,,,F10A1_CHICK,Gallus gallus (Chicken), comp142525_c0_seq1,3001,42.6858,0.51304969,354,1306,,3.00E-127,Q8BTZ4,Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5),Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5),GO:0005680; GO:0051301; GO:0007067; GO:0070979,anaphase-promoting complex; cell division; mitosis; protein K11-linked ubiquitination,PF12862;,1.00E-53,CHOYP_BRAFLDRAFT_100007.1.1,,,,,,,APC5_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979] comp142526_c0_seq5,2452,41.8842,0.36998498,11,4,,,,,,,,,2.00E-79,CHOYP_BRAFLDRAFT_124260.1.1,,,,,,,,, comp142527_c1_seq4,2022,36.0534,0.71624123,15,9,,3.00E-28,Q8SQZ4,Probable dual specificity protein kinase YAK1 homolog (EC 2.7.12.1),Probable dual specificity protein kinase YAK1 homolog (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0005634; GO:0004674; GO:0004712,ATP binding; cytoplasm; nucleus; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity,PF00069;,1.00E-132,CHOYP_DOA.2.2,,,,,,,YAK1_ENCCU,Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite), comp142527_c1_seq5,2357,38.5235,0.88104635,64,201,,1.00E-139,P49760,Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2),Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2),GO:0005524; GO:0045721; GO:0016607; GO:0005634; GO:0046777; GO:0004674; GO:0004712; GO:0004713; GO:0043484; GO:0010212; GO:0032526,ATP binding; negative regulation of gluconeogenesis; nuclear speck; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; regulation of RNA splicing; response to ionizing radiation; response to retinoic acid,PF00069;,5.00E-151,CHOYP_CLK2.1.1,,,,,,,CLK2_HUMAN,Homo sapiens (Human),negative regulation of gluconeogenesis [GO:0045721]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212]; response to retinoic acid [GO:0032526] comp142527_c1_seq6,662,39.2749,0.70653172,1,5,,9.00E-48,P32350,Dual specificity protein kinase KNS1 (EC 2.7.12.1),Dual specificity protein kinase KNS1 (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0016480; GO:0005634; GO:0046777; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; negative regulation of transcription from RNA polymerase III promoter; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00069;,,,,,,,,,KNS1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp142528_c2_seq1,3807,41.5813,0.55658052,0,0,,0,Q5PYH5,Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B),Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B),GO:0007015; GO:0016323; GO:0016337; GO:0030866; GO:0001935; GO:0045930; GO:0019902; GO:0019901; GO:0050808; GO:0007268,actin filament organization; basolateral plasma membrane; cell-cell adhesion; cortical actin cytoskeleton organization; endothelial cell proliferation; negative regulation of mitotic cell cycle; phosphatase binding; protein kinase binding; synapse organization; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,0,CHOYP_SAP.1.2,,,,,,,DLG1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament organization [GO:0007015]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; single organismal cell-cell adhesion [GO:0016337]; synapse organization [GO:0050808] comp142528_c2_seq2,3819,41.5816,0.54887631,0,0,,0,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,,,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp142528_c2_seq3,3774,41.5739,0.54366183,7,36,,0,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,0,CHOYP_SAP.1.2,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp142528_c2_seq4,3762,41.5205,0.55916997,0,15,,0,Q5PYH5,Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B),Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B),GO:0007015; GO:0016323; GO:0016337; GO:0030866; GO:0001935; GO:0045930; GO:0019902; GO:0019901; GO:0050808; GO:0007268,actin filament organization; basolateral plasma membrane; cell-cell adhesion; cortical actin cytoskeleton organization; endothelial cell proliferation; negative regulation of mitotic cell cycle; phosphatase binding; protein kinase binding; synapse organization; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,2.00E-18,CHOYP_SAP.2.2,7.00E-118,ruditapes_c13576,,,,,DLG1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament organization [GO:0007015]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; single organismal cell-cell adhesion [GO:0016337]; synapse organization [GO:0050808] comp142528_c2_seq5,881,41.6572,0.60483083,5,19,,,,,,,,,2.00E-93,CHOYP_SAP.1.2,,,,,,,,, comp142528_c2_seq7,493,48.073,0.42276597,1,0,,2.00E-16,Q9D6K5,Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Activin receptor-interacting protein 4) (Mitochondrial outer membrane protein 25),Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Activin receptor-interacting protein 4) (Mitochondrial outer membrane protein 25),GO:0009986; GO:0006897; GO:0031307; GO:0048312; GO:0032926; GO:0048471; GO:0032927; GO:2000010; GO:0002092,cell surface; endocytosis; integral to mitochondrial outer membrane; intracellular distribution of mitochondria; negative regulation of activin receptor signaling pathway; perinuclear region of cytoplasm; positive regulation of activin receptor signaling pathway; positive regulation of protein localization to cell surface; positive regulation of receptor internalization,PF00595;,,,,,,,,,SYJ2B_MOUSE,Mus musculus (Mouse),cytoplasm organization [GO:0007028]; endocytosis [GO:0006897]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of receptor internalization [GO:0002092]; protein targeting [GO:0006605]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266] comp142529_c0_seq10,1243,44.8914,0.36757475,0,0,,4.00E-79,Q2PW47,Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Protein lessen) (Thyroid hormone receptor-associated protein 4 homolog) (Trap100 homolog),Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Protein lessen) (Thyroid hormone receptor-associated protein 4 homolog) (Trap100 homolog),GO:0048484; GO:0005634; GO:0006355; GO:0046549; GO:0048538; GO:0006351,"enteric nervous system development; nucleus; regulation of transcription, DNA-dependent; retinal cone cell development; thymus development; transcription, DNA-dependent",PF11277;,,,,,,,,,MED24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"enteric nervous system development [GO:0048484]; interstitial cell of Cajal differentiation [GO:0061453]; retinal cone cell development [GO:0046549]; thymus development [GO:0048538]; transcription, DNA-templated [GO:0006351]" comp142529_c0_seq11,1608,44.9627,0.34489319,0,0,,1.00E-107,Q2PW47,Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Protein lessen) (Thyroid hormone receptor-associated protein 4 homolog) (Trap100 homolog),Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Protein lessen) (Thyroid hormone receptor-associated protein 4 homolog) (Trap100 homolog),GO:0048484; GO:0005634; GO:0006355; GO:0046549; GO:0048538; GO:0006351,"enteric nervous system development; nucleus; regulation of transcription, DNA-dependent; retinal cone cell development; thymus development; transcription, DNA-dependent",PF11277;,,,,,,,,,MED24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"enteric nervous system development [GO:0048484]; interstitial cell of Cajal differentiation [GO:0061453]; retinal cone cell development [GO:0046549]; thymus development [GO:0048538]; transcription, DNA-templated [GO:0006351]" comp142529_c0_seq3,1779,41.7088,0.50435936,188,955,,,,,,,,,7.00E-53,CHOYP_MED24.4.10,,,,,,,,, comp142531_c0_seq1,2699,46.9433,0.53359691,0,0,,3.00E-169,Q709C8,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,0,CHOYP_BRAFLDRAFT_226506.3.3,,,,,,,VP13C_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq13,2481,47.4809,0.53937358,0,0,,2.00E-170,Q709C8,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq14,713,44.7405,0.75802765,0,0,,1.00E-12,Q555C6,Putative vacuolar protein sorting-associated protein 13B,Putative vacuolar protein sorting-associated protein 13B,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF12624;PF16908;PF16909;PF16910;,,,,,,,,,VP13B_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq15,2118,43.4844,0.54194385,0,0,,7.00E-30,Q54LN2,Putative vacuolar protein sorting-associated protein 13D,Putative vacuolar protein sorting-associated protein 13D,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF09333;PF12624;PF16908;PF16909;,3.00E-147,CHOYP_BRAFLDRAFT_226506.1.3,,,,,,,VP13D_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq2,1668,46.3429,0.56168289,0,0,,2.00E-30,Q54LN2,Putative vacuolar protein sorting-associated protein 13D,Putative vacuolar protein sorting-associated protein 13D,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF09333;PF12624;PF16908;PF16909;,5.00E-149,CHOYP_BRAFLDRAFT_226506.3.3,,,,,,,VP13D_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq3,1667,42.4715,0.61920497,0,0,,,,,,,,,1.00E-48,CHOYP_LOC100644563.1.1,,,,,,,,, comp142531_c0_seq4,1221,48.4848,0.6051863,0,0,,1.00E-10,Q7Z7G8,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp142531_c0_seq5,1450,47.1724,0.57597677,0,0,,,,,,,,,5.00E-149,CHOYP_BRAFLDRAFT_226506.3.3,9.00E-23,ruditapes_c17718,,,,,,, comp142531_c0_seq6,1381,40.2607,0.61236689,0,0,,8.00E-12,Q555C6,Putative vacuolar protein sorting-associated protein 13B,Putative vacuolar protein sorting-associated protein 13B,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF12624;PF16908;PF16909;PF16910;,,,,,,,,,VP13B_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq7,3149,44.9349,0.52441808,0,0,,3.00E-167,Q709C8,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp142531_c0_seq8,1889,43.8857,0.56282177,0,0,,7.00E-10,Q7Z7G8,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp142531_c0_seq9,1217,46.0148,0.66350491,0,0,,,,,,,,,1.00E-48,CHOYP_LOC100644563.1.1,,,,,,,,, comp142532_c0_seq3,560,30.1786,1.65464011,0,0,,,,,,,,,,,8.00E-19,ruditapes_c12312,,,,,,, comp142533_c0_seq1,914,35.2298,0.70993606,103,409,,,,,,,,,,,6.00E-23,ruditapes_c2313,,,,,,, comp142534_c0_seq1,3544,45.8239,0.56283509,1460,159,,0,Q4G0X9,Coiled-coil domain-containing protein 40,Coiled-coil domain-containing protein 40,GO:0070286; GO:0005929; GO:0005737; GO:0071907; GO:0071910; GO:0035469; GO:0060287; GO:0001947; GO:0030324; GO:0003356,axonemal dynein complex assembly; cilium; cytoplasm; determination of digestive tract left/right asymmetry; determination of liver left/right asymmetry; determination of pancreatic left/right asymmetry; epithelial cilium movement involved in determination of left/right asymmetry; heart looping; lung development; regulation of cilium beat frequency,PF08647;,0,CHOYP_LOC100374249.1.1,,,,,,,CCD40_HUMAN,Homo sapiens (Human),axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement [GO:0003351]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; regulation of cilium beat frequency [GO:0003356]; sperm motility [GO:0030317] comp142534_c0_seq2,685,38.3942,0.75620955,0,0,,8.00E-15,Q4G0X9,Coiled-coil domain-containing protein 40,Coiled-coil domain-containing protein 40,GO:0070286; GO:0005929; GO:0005737; GO:0071907; GO:0071910; GO:0035469; GO:0060287; GO:0001947; GO:0030324; GO:0003356,axonemal dynein complex assembly; cilium; cytoplasm; determination of digestive tract left/right asymmetry; determination of liver left/right asymmetry; determination of pancreatic left/right asymmetry; epithelial cilium movement involved in determination of left/right asymmetry; heart looping; lung development; regulation of cilium beat frequency,PF08647;,,,,,,,,,CCD40_HUMAN,Homo sapiens (Human),axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement [GO:0003351]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; regulation of cilium beat frequency [GO:0003356]; sperm motility [GO:0030317] comp142535_c1_seq4,2319,39.5429,0.39763862,16,41,,5.00E-66,Q9Z0E1,Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37),Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37),GO:0006396; GO:0030154; GO:0031497; GO:0005737; GO:0007292; GO:0016021; GO:0051308; GO:0007283,RNA processing; cell differentiation; chromatin assembly; cytoplasm; female gamete generation; integral to membrane; male meiosis chromosome separation; spermatogenesis,,,,,,,,,,CB065_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chromatin assembly [GO:0031497]; female gamete generation [GO:0007292]; male meiosis chromosome separation [GO:0051308]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283] comp142535_c1_seq8,2202,39.6458,0.40501437,0,0,,3.00E-60,Q9Z0E1,Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37),Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37),GO:0006396; GO:0030154; GO:0031497; GO:0005737; GO:0007292; GO:0016021; GO:0051308; GO:0007283,RNA processing; cell differentiation; chromatin assembly; cytoplasm; female gamete generation; integral to membrane; male meiosis chromosome separation; spermatogenesis,,,,,,,,,,CB065_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chromatin assembly [GO:0031497]; female gamete generation [GO:0007292]; male meiosis chromosome separation [GO:0051308]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283] comp142538_c0_seq2,1263,40.0633,0.4936886,3,56,,1.00E-57,Q8IW92,Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),GO:0004565; GO:0005975; GO:0005576,beta-galactosidase activity; carbohydrate metabolic process; extracellular region,PF01301;,5.00E-15,CHOYP_BRAFLDRAFT_114709.1.1,,,,,,,GLBL2_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975] comp142538_c0_seq3,823,38.5176,0.45923635,10,50,,,,,,,,,,,2.00E-29,ruditapes_c14009,,,,,,, comp142540_c0_seq1,1695,40.413,0.45236333,3,24,,5.00E-76,Q96I76,G patch domain-containing protein 3,G patch domain-containing protein 3,GO:0003676,nucleic acid binding,PF01585;,,,,,,,,,GPTC3_HUMAN,Homo sapiens (Human), comp142540_c0_seq2,2514,39.2999,0.49187933,72,338,,7.00E-72,Q8BIY1,G patch domain-containing protein 3,G patch domain-containing protein 3,GO:0003676,nucleic acid binding,PF01585;,6.00E-94,CHOYP_LOC100375338.1.1,,,,,,,GPTC3_MOUSE,Mus musculus (Mouse), comp142541_c2_seq1,967,38.5729,0.69998918,1,173,,4.00E-45,P34147,Rho-related protein racA,Rho-related protein racA,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00651;PF00071;,2.00E-38,CHOYP_LOC752289.1.1,,,,,,,RACA_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp142542_c1_seq10,2919,47.345,0.45586503,88,0,,1.00E-10,Q9PVV4,Pericentriolar material 1 protein (PCM-1) (xPCM-1),Pericentriolar material 1 protein (PCM-1) (xPCM-1),GO:0034451; GO:0042384,centriolar satellite; cilium assembly,PF15717;,5.00E-64,CHOYP_LOC581113.2.2,,,,,,,PCM1_XENLA,Xenopus laevis (African clawed frog),cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp142542_c1_seq12,2806,47.7904,0.5382263,0,0,,1.00E-11,Q15154,Pericentriolar material 1 protein (PCM-1) (hPCM-1),Pericentriolar material 1 protein (PCM-1) (hPCM-1),GO:0000086; GO:0034451; GO:0051297; GO:0042384; GO:0005829; GO:0042802; GO:0022027; GO:0034453; GO:0034454; GO:0050768; GO:0097150; GO:0031965; GO:0000242; GO:0071539,G2/M transition of mitotic cell cycle; centriolar satellite; centrosome organization; cilium assembly; cytosol; identical protein binding; interkinetic nuclear migration; microtubule anchoring; microtubule anchoring at centrosome; negative regulation of neurogenesis; neuronal stem cell maintenance; nuclear membrane; pericentriolar material; protein localization to centrosome,PF15717;,,,,,,,,,PCM1_HUMAN,Homo sapiens (Human),centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; G2/M transition of mitotic cell cycle [GO:0000086]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp142542_c1_seq14,206,45.6311,0.57501355,3,0,,7.00E-06,Q2TL32,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1),GO:0005737; GO:0005856; GO:0016021; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_RAT,Rattus norvegicus (Rat),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp142542_c1_seq3,4473,47.239,0.51849772,0,0,,2.00E-11,Q15154,Pericentriolar material 1 protein (PCM-1) (hPCM-1),Pericentriolar material 1 protein (PCM-1) (hPCM-1),GO:0000086; GO:0034451; GO:0051297; GO:0042384; GO:0005829; GO:0042802; GO:0022027; GO:0034453; GO:0034454; GO:0050768; GO:0097150; GO:0031965; GO:0000242; GO:0071539,G2/M transition of mitotic cell cycle; centriolar satellite; centrosome organization; cilium assembly; cytosol; identical protein binding; interkinetic nuclear migration; microtubule anchoring; microtubule anchoring at centrosome; negative regulation of neurogenesis; neuronal stem cell maintenance; nuclear membrane; pericentriolar material; protein localization to centrosome,PF15717;,,,,,,,,,PCM1_HUMAN,Homo sapiens (Human),centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; G2/M transition of mitotic cell cycle [GO:0000086]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] comp142542_c1_seq5,3361,47.0991,0.44717338,0,0,,,,,,,,,5.00E-64,CHOYP_LOC581113.2.2,,,,,,,,, comp142542_c1_seq6,4380,47.2831,0.52412734,0,0,,7.00E-11,Q9R0L6,Pericentriolar material 1 protein (PCM-1) (mPCM-1),Pericentriolar material 1 protein (PCM-1) (mPCM-1),GO:0034451; GO:0042384; GO:0022027; GO:0034454; GO:0050768; GO:0097150; GO:0000242; GO:0071539,centriolar satellite; cilium assembly; interkinetic nuclear migration; microtubule anchoring at centrosome; negative regulation of neurogenesis; neuronal stem cell maintenance; pericentriolar material; protein localization to centrosome,PF15717;,7.00E-64,CHOYP_LOC581113.2.2,,,,,,,PCM1_MOUSE,Mus musculus (Mouse),centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; social behavior [GO:0035176] comp142543_c0_seq3,2319,32.2122,0.43458221,0,0,,,,,,,,,,,3.00E-19,ruditapes_c21185,,,,,,, comp142543_c0_seq4,2945,34.4312,0.392234,10,107,,5.00E-169,Q9XZ58,COP9 signalosome complex subunit 5 (Dch5) (Signalosome subunit 5) (EC 3.4.-.-) (JAB1 homolog),COP9 signalosome complex subunit 5 (Dch5) (Signalosome subunit 5) (EC 3.4.-.-) (JAB1 homolog),GO:0008180; GO:0019781; GO:0007409; GO:0001751; GO:0005737; GO:0008347; GO:0046872; GO:0008237; GO:0007095; GO:0035207; GO:0035204; GO:0032435; GO:0034399; GO:0007314; GO:0007310; GO:0045787; GO:0000338; GO:0050821; GO:0006508,COP9 signalosome; NEDD8 activating enzyme activity; axonogenesis; compound eye photoreceptor cell differentiation; cytoplasm; glial cell migration; metal ion binding; metallopeptidase activity; mitotic G2 DNA damage checkpoint; negative regulation of hemocyte proliferation; negative regulation of lamellocyte differentiation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nuclear periphery; oocyte anterior/posterior axis specification; oocyte dorsal/ventral axis specification; positive regulation of cell cycle; protein deneddylation; protein stabilization; proteolysis,PF01398;,0,CHOYP_CSN5.1.1,,,,,,,CSN5_DROME,Drosophila melanogaster (Fruit fly),axonogenesis [GO:0007409]; compound eye photoreceptor cell differentiation [GO:0001751]; cullin deneddylation [GO:0010388]; female germ-line stem cell population maintenance [GO:0036099]; germarium-derived cystoblast division [GO:0048142]; germ cell development [GO:0007281]; glial cell migration [GO:0008347]; male germ-line cyst encapsulation [GO:0048140]; mitotic G2 DNA damage checkpoint [GO:0007095]; multicellular organism development [GO:0007275]; negative regulation of hemocyte proliferation [GO:0035207]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oogenesis [GO:0048477]; positive regulation of cell cycle [GO:0045787]; positive regulation of cyclin catabolic process [GO:2000600]; protein deneddylation [GO:0000338]; protein stabilization [GO:0050821] comp142543_c0_seq5,2936,34.4346,0.3930675,3,45,,0,Q6P635,COP9 signalosome complex subunit 5 (Signalosome subunit 5) (EC 3.4.-.-),COP9 signalosome complex subunit 5 (Signalosome subunit 5) (EC 3.4.-.-),GO:0008180; GO:0046872; GO:0008237; GO:0048471; GO:0006508,COP9 signalosome; metal ion binding; metallopeptidase activity; perinuclear region of cytoplasm; proteolysis,PF01398;,0,CHOYP_CSN5.1.1,,,,,,,CSN5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142544_c1_seq6,493,41.9878,0.69252621,4,68,,7.00E-06,P78560,Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),GO:0006977; GO:0071260; GO:0005737; GO:0008625; GO:0005634; GO:0042981,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular response to mechanical stimulus; cytoplasm; extrinsic apoptotic signaling pathway via death domain receptors; nucleus; regulation of apoptotic process",PF00619;PF00531;,,,,,,,,,CRADD_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]" comp142544_c3_seq1,1646,39.5504,0.42420934,0,0,,5.00E-49,Q66K94,SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1),SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1),GO:0070876; GO:0000724; GO:0007093; GO:0010212; GO:0003697,SOSS complex; double-strand break repair via homologous recombination; mitotic cell cycle checkpoint; response to ionizing radiation; single-stranded DNA binding,PF01336;,8.00E-39,CHOYP_SOSB1.2.2,,,,,,,SOSB1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212] comp142544_c3_seq2,1775,38.5352,0.44398866,14,17,,,,,,,,,1.00E-31,CHOYP_SOSB1.1.2,,,,,,,,, comp142547_c0_seq1,1659,44.9066,0.382985,1,33,,3.00E-73,Q5ZL91,Integrator complex subunit 7 (Int7),Integrator complex subunit 7 (Int7),GO:0005694; GO:0005634; GO:0006974,chromosome; nucleus; response to DNA damage stimulus,,,,,,,,,,INT7_CHICK,Gallus gallus (Chicken),cellular response to DNA damage stimulus [GO:0006974]; snRNA processing [GO:0016180] comp142547_c0_seq4,378,43.6508,0.66882821,8,49,,8.00E-24,Q54PL2,Integrator complex subunit 7 homolog,Integrator complex subunit 7 homolog,GO:0005634,nucleus,,9.00E-31,CHOYP_INT7.1.1,,,,,,,INT7_DICDI,Dictyostelium discoideum (Slime mold),snRNA processing [GO:0016180] comp142549_c1_seq2,1966,36.7752,0.42654245,48,775,,,,,,,,,1.00E-13,CHOYP_SELL.1.1,5.00E-47,ruditapes_c11240,,,,,,, comp142551_c0_seq8,1289,39.6431,0.39730228,126,373,,0,Q17IE8,Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit Cdk8) (Mediator of RNA polymerase II transcription subunit Cdk8),Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit Cdk8) (Mediator of RNA polymerase II transcription subunit Cdk8),GO:0005524; GO:0000082; GO:0008353; GO:0004693; GO:0005634; GO:0006468; GO:0006355; GO:0006351,"ATP binding; G1/S transition of mitotic cell cycle; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein serine/threonine kinase activity; nucleus; protein phosphorylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;,0,CHOYP_CDK8.1.1,,,,,,,CDK8_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"G1/S transition of mitotic cell cycle [GO:0000082]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142552_c0_seq1,1381,40.1883,0.54228715,148,469,,3.00E-98,Q4KLT3,Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19),Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19),GO:0005737; GO:0046872; GO:0008168; GO:0008033,cytoplasm; metal ion binding; methyltransferase activity; tRNA processing,PF07757;,3.00E-56,CHOYP_TRM44.1.1,,,,,,,TRM44_XENLA,Xenopus laevis (African clawed frog),tRNA processing [GO:0008033] comp142553_c0_seq3,1760,35.3409,0.33830697,36,34,,,,,,,,,,,5.00E-84,ruditapes2_c143,,,,,,, comp142553_c0_seq5,2557,33.8287,0.30685516,387,1364,,1.00E-70,O18883,Thioredoxin domain-containing protein 9 (Protein 1-4),Thioredoxin domain-containing protein 9 (Protein 1-4),GO:0045454,cell redox homeostasis,PF00085;,8.00E-73,CHOYP_TXNDC9.1.1,5.00E-54,ruditapes_c33874,,,,,TXND9_BOVIN,Bos taurus (Bovine),cell redox homeostasis [GO:0045454]; queuosine biosynthetic process [GO:0008616] comp142554_c0_seq3,3323,36.0217,0.49654416,1,14,,0,Q62909,Kinesin-like protein KIF2C (Kinesin-related protein 2) (Mitotic centromere-associated kinesin) (MCAK),Kinesin-like protein KIF2C (Kinesin-related protein 2) (Mitotic centromere-associated kinesin) (MCAK),GO:0005524; GO:0051301; GO:0007059; GO:0000777; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0051010; GO:0007018; GO:0007067; GO:0005634,ATP binding; cell division; chromosome segregation; condensed chromosome kinetochore; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule plus-end binding; microtubule-based movement; mitosis; nucleus,PF00225;,0,CHOYP_KIF2A.2.2,,,,,,,KIF2C_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080] comp142554_c0_seq4,3849,37.3344,0.53077775,8,27,,0,Q960Z0,Kinesin-like protein Klp10A (Kinesin-like protein at cytological position 10A),Kinesin-like protein Klp10A (Kinesin-like protein at cytological position 10A),GO:0005524; GO:0051301; GO:0051298; GO:0007059; GO:0000775; GO:0005737; GO:0005871; GO:0005828; GO:0072687; GO:0000212; GO:0003777; GO:0005815; GO:0007018; GO:0007067; GO:0007052; GO:0097431; GO:0003774,"ATP binding; cell division; centrosome duplication; chromosome segregation; chromosome, centromeric region; cytoplasm; kinesin complex; kinetochore microtubule; meiotic spindle; meiotic spindle organization; microtubule motor activity; microtubule organizing center; microtubule-based movement; mitosis; mitotic spindle organization; mitotic spindle pole; motor activity",PF00225;,,,,,,,,,KI10A_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; centrosome duplication [GO:0051298]; establishment of meiotic spindle orientation [GO:0051296]; meiotic spindle organization [GO:0000212]; microtubule depolymerization [GO:0007019]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051] comp142554_c0_seq5,3755,36.8309,0.51739995,34,11,,0,Q5ZKV8,Kinesin-like protein KIF2A,Kinesin-like protein KIF2A,GO:0005524; GO:0030154; GO:0051301; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0005815; GO:0007018; GO:0007067; GO:0007052; GO:0007399; GO:0000922,ATP binding; cell differentiation; cell division; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule organizing center; microtubule-based movement; mitosis; mitotic spindle organization; nervous system development; spindle pole,PF00225;,2.00E-26,CHOYP_KIF2A.1.2,,,,,,,KIF2A_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; nervous system development [GO:0007399] comp142554_c0_seq6,3597,37.1699,0.54658201,3,0,,0,Q5ZKV8,Kinesin-like protein KIF2A,Kinesin-like protein KIF2A,GO:0005524; GO:0030154; GO:0051301; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0005815; GO:0007018; GO:0007067; GO:0007052; GO:0007399; GO:0000922,ATP binding; cell differentiation; cell division; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule organizing center; microtubule-based movement; mitosis; mitotic spindle organization; nervous system development; spindle pole,PF00225;,0,CHOYP_KIF2A.2.2,,,,,,,KIF2A_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; nervous system development [GO:0007399] comp142554_c0_seq7,357,38.0952,0.63042537,9,0,,,,,,,,,5.00E-34,CHOYP_KIF2A.2.2,2.00E-17,ruditapes_c22453,,,,,,, comp142556_c0_seq1,1238,36.3489,0.50464354,39,585,,2.00E-32,Q28F39,Coiled-coil domain-containing protein 134,Coiled-coil domain-containing protein 134,GO:0005576,extracellular region,PF15002;,,,,,,,,,CC134_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp142556_c1_seq1,4216,42.1015,0.45598123,1352,5237,,0,Q9H0H0,Integrator complex subunit 2 (Int2),Integrator complex subunit 2 (Int2),GO:0016021; GO:0032039; GO:0031965; GO:0016180,integral to membrane; integrator complex; nuclear membrane; snRNA processing,PF14750;,8.00E-63,CHOYP_INTS2.1.1,8.00E-105,ruditapes_c11059,,,,,INT2_HUMAN,Homo sapiens (Human),snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp142561_c0_seq1,1609,44.2511,0.69434978,11,35,,2.00E-138,Q5R7X2,U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140),U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140),GO:0003723; GO:0006396; GO:0000166; GO:0005634,RNA binding; RNA processing; nucleotide binding; nucleus,PF08312;PF00076;PF01805;,4.00E-106,CHOYP_SR140.1.2,,,,,,,SR140_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),RNA processing [GO:0006396] comp142561_c0_seq5,1688,43.0687,0.66690691,2,15,,7.00E-08,P29341,Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1),Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1),GO:0008380; GO:0010494; GO:0031047; GO:0006397; GO:2000623; GO:0000184; GO:0000166; GO:0008143; GO:1900153; GO:0060213; GO:0005681,"RNA splicing; cytoplasmic stress granule; gene silencing by RNA; mRNA processing; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleotide binding; poly(A) RNA binding; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; spliceosomal complex",PF00658;PF00076;,5.00E-86,CHOYP_SR140.1.2,,,,,,,PABP1_MOUSE,Mus musculus (Mouse),"gene silencing by RNA [GO:0031047]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; RNA splicing [GO:0008380]" comp142561_c0_seq6,1331,42.8249,0.66847373,0,0,,1.00E-09,Q93W34,Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C),Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C),GO:0005829; GO:0006397; GO:0000166; GO:0005634; GO:0008143,cytosol; mRNA processing; nucleotide binding; nucleus; poly(A) RNA binding,PF00076;,,,,,,,,,RP45C_ARATH,Arabidopsis thaliana (Mouse-ear cress),mRNA processing [GO:0006397] comp142562_c0_seq1,2108,41.129,0.94573003,0,0,,1.00E-22,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp142562_c0_seq10,969,39.8349,0.93747583,0,0,,5.00E-19,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp142562_c0_seq11,3108,42.0528,0.88497993,0,0,,4.00E-23,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp142562_c0_seq12,2093,41.0416,0.94524414,0,0,,4.00E-08,P01266,Thyroglobulin (Tg),Thyroglobulin (Tg),GO:0005615; GO:0042446; GO:0015705; GO:0031641; GO:0007165; GO:0030878; GO:0006590,extracellular space; hormone biosynthetic process; iodide transport; regulation of myelination; signal transduction; thyroid gland development; thyroid hormone generation,PF00135;PF07699;PF00086;,,,,,,,,,THYG_HUMAN,Homo sapiens (Human),hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; transcytosis [GO:0045056] comp142562_c0_seq13,2361,42.5667,0.87651145,0,0,,3.00E-25,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp142562_c0_seq2,2616,42.6988,0.92684904,0,0,,2.00E-12,Q8JZM4,Delta and Notch-like epidermal growth factor-related receptor (Brain EGF repeat-containing transmembrane protein),Delta and Notch-like epidermal growth factor-related receptor (Brain EGF repeat-containing transmembrane protein),GO:0007220; GO:0007219; GO:0005509; GO:0007417; GO:0030425; GO:0005769; GO:0010001; GO:0016021; GO:0043025; GO:0005886; GO:0048741,Notch receptor processing; Notch signaling pathway; calcium ion binding; central nervous system development; dendrite; early endosome; glial cell differentiation; integral to membrane; neuronal cell body; plasma membrane; skeletal muscle fiber development,PF00008;PF12661;,,,,,,,,,DNER_MOUSE,Mus musculus (Mouse),central nervous system development [GO:0007417]; glial cell differentiation [GO:0010001]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; skeletal muscle fiber development [GO:0048741] comp142562_c0_seq4,954,39.6226,0.93572511,0,0,,4.00E-19,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp142562_c0_seq5,4755,42.8601,0.89883702,0,0,,8.00E-23,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp142562_c0_seq6,3093,41.9981,0.8842738,0,0,,8.00E-22,P78539,Sushi repeat-containing protein SRPX,Sushi repeat-containing protein SRPX,GO:0005776; GO:0006914; GO:0007155; GO:0009986; GO:0033554; GO:0005783; GO:0016020; GO:0060244; GO:0001845; GO:0043065,autophagic vacuole; autophagy; cell adhesion; cell surface; cellular response to stress; endoplasmic reticulum; membrane; negative regulation of cell proliferation involved in contact inhibition; phagolysosome assembly; positive regulation of apoptotic process,PF13778;PF02494;PF00084;,,,,,,,,,SRPX_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; cell adhesion [GO:0007155]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; phagolysosome assembly [GO:0001845]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; response to endoplasmic reticulum stress [GO:0034976] comp142562_c0_seq9,3755,42.53,0.93648696,3,2,,1.00E-15,Q5G872,"Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein You)","Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein You)",GO:0008015; GO:0005509; GO:0009897; GO:0005615; GO:0042694; GO:0048747; GO:0007517; GO:0030514; GO:0030141; GO:0007224; GO:0001756,blood circulation; calcium ion binding; external side of plasma membrane; extracellular space; muscle cell fate specification; muscle fiber development; muscle organ development; negative regulation of BMP signaling pathway; secretory granule; smoothened signaling pathway; somitogenesis,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),blood circulation [GO:0008015]; muscle cell fate specification [GO:0042694]; muscle fiber development [GO:0048747]; muscle organ development [GO:0007517]; smoothened signaling pathway [GO:0007224]; somitogenesis [GO:0001756]; striated muscle cell differentiation [GO:0051146] comp142566_c0_seq1,2717,37.0261,0.48461874,11,13,,5.00E-14,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp142566_c0_seq2,2544,37.3821,0.46328205,0,16,,1.00E-166,Q3SZ25,Polycomb protein EED,Polycomb protein EED,GO:0035098; GO:0003682; GO:0042054; GO:0061087; GO:0045120; GO:0006349; GO:0006355; GO:0001739; GO:0006351,"ESC/E(Z) complex; chromatin binding; histone methyltransferase activity; positive regulation of histone H3-K27 methylation; pronucleus; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; sex chromatin; transcription, DNA-dependent",PF00400;,4.00E-115,CHOYP_EED.1.1,,,,,,,EED_BOVIN,Bos taurus (Bovine),"positive regulation of histone H3-K27 methylation [GO:0061087]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142566_c0_seq3,2746,37.0357,0.47946992,4,10,,5.00E-14,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp142566_c0_seq4,2515,37.3757,0.48007422,10,10,,9.00E-167,Q3SZ25,Polycomb protein EED,Polycomb protein EED,GO:0035098; GO:0003682; GO:0042054; GO:0061087; GO:0045120; GO:0006349; GO:0006355; GO:0001739; GO:0006351,"ESC/E(Z) complex; chromatin binding; histone methyltransferase activity; positive regulation of histone H3-K27 methylation; pronucleus; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; sex chromatin; transcription, DNA-dependent",PF00400;,5.00E-114,CHOYP_EED.1.1,,,,,,,EED_BOVIN,Bos taurus (Bovine),"positive regulation of histone H3-K27 methylation [GO:0061087]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142568_c1_seq10,1412,35.0567,0.32297159,10,9,,1.00E-51,P52552,Peroxiredoxin-2 (EC 1.11.1.15) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Fragment),Peroxiredoxin-2 (EC 1.11.1.15) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Fragment),GO:0005737; GO:0004601; GO:0051920,cytoplasm; peroxidase activity; peroxiredoxin activity,PF00578;,1.00E-61,CHOYP_ISCW_ISCW013767.1.1,,,,,,,PRDX2_PIG,Sus scrofa (Pig),removal of superoxide radicals [GO:0019430] comp142568_c1_seq2,2023,37.1725,0.38658753,0,19,,2.00E-103,Q9BGI2,Peroxiredoxin-4 (EC 1.11.1.15) (Peroxiredoxin IV) (Prx-IV),Peroxiredoxin-4 (EC 1.11.1.15) (Peroxiredoxin IV) (Prx-IV),GO:0005576; GO:0005739; GO:0004601; GO:0051920; GO:0072593,extracellular region; mitochondrion; peroxidase activity; peroxiredoxin activity; reactive oxygen species metabolic process,PF10417;PF00578;,,,,,,,,,PRDX4_BOVIN,Bos taurus (Bovine),4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; spermatogenesis [GO:0007283] comp142568_c1_seq3,2000,36.9,0.35282717,5,15,,2.00E-87,Q9BGI3,Peroxiredoxin-2 (EC 1.11.1.15),Peroxiredoxin-2 (EC 1.11.1.15),GO:0005737; GO:0004601; GO:0051920; GO:0042981; GO:0019430,cytoplasm; peroxidase activity; peroxiredoxin activity; regulation of apoptotic process; removal of superoxide radicals,PF10417;PF00578;,1.00E-81,CHOYP_ISCW_ISCW013767.1.1,,,,,,,PRDX2_BOVIN,Bos taurus (Bovine),regulation of apoptotic process [GO:0042981]; removal of superoxide radicals [GO:0019430] comp142569_c3_seq1,1590,48.6792,0.6816946,0,0,,3.00E-23,P95141,Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),GO:0005524; GO:0071766; GO:0016878; GO:0070566; GO:0006633; GO:0097040,ATP binding; Actinobacterium-type cell wall biogenesis; acid-thiol ligase activity; adenylyltransferase activity; fatty acid biosynthetic process; phthiocerol biosynthetic process,PF00501;,,,,,,,,,FAA29_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),Actinobacterium-type cell wall biogenesis [GO:0071766]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; phthiocerol biosynthetic process [GO:0097040] comp142569_c3_seq2,4572,48.9064,0.65281473,0,0,,0,Q9Y2E4,Disco-interacting protein 2 homolog C (DIP2 homolog C),Disco-interacting protein 2 homolog C (DIP2 homolog C),GO:0003824; GO:0005634,catalytic activity; nucleus,PF00501;PF06464;,0,CHOYP_LOC100117775.2.2,,,,,,,DIP2C_HUMAN,Homo sapiens (Human),metabolic process [GO:0008152] comp142569_c3_seq3,4539,48.7552,0.64702031,0,0,,0,Q9W0S9,Disco-interacting protein 2,Disco-interacting protein 2,GO:0003824; GO:0007275; GO:0005634,catalytic activity; multicellular organismal development; nucleus,PF00501;PF06464;,0,CHOYP_LOC100117775.1.2,,,,,,,DIP2_DROME,Drosophila melanogaster (Fruit fly),metabolic process [GO:0008152]; multicellular organism development [GO:0007275] comp142569_c3_seq4,5239,47.4518,0.64352343,0,0,,0,Q9Y2E4,Disco-interacting protein 2 homolog C (DIP2 homolog C),Disco-interacting protein 2 homolog C (DIP2 homolog C),GO:0003824; GO:0005634,catalytic activity; nucleus,PF00501;PF06464;,0,CHOYP_LOC100117775.2.2,,,,,,,DIP2C_HUMAN,Homo sapiens (Human),metabolic process [GO:0008152] comp142569_c3_seq5,2257,45.5029,0.67254744,0,0,,2.00E-23,P95141,Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),GO:0005524; GO:0071766; GO:0016878; GO:0070566; GO:0006633; GO:0097040,ATP binding; Actinobacterium-type cell wall biogenesis; acid-thiol ligase activity; adenylyltransferase activity; fatty acid biosynthetic process; phthiocerol biosynthetic process,PF00501;,,,,,,,,,FAA29_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),Actinobacterium-type cell wall biogenesis [GO:0071766]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; phthiocerol biosynthetic process [GO:0097040] comp142569_c3_seq6,5206,47.426,0.65537429,0,0,,0,Q9Y2E4,Disco-interacting protein 2 homolog C (DIP2 homolog C),Disco-interacting protein 2 homolog C (DIP2 homolog C),GO:0003824; GO:0005634,catalytic activity; nucleus,PF00501;PF06464;,0,CHOYP_LOC100117775.1.2,,,,,,,DIP2C_HUMAN,Homo sapiens (Human),metabolic process [GO:0008152] comp142569_c3_seq8,1505,49.7674,0.6901829,0,0,,2.00E-15,Q7U226,Long-chain-fatty-acid--AMP ligase FadD30 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),Long-chain-fatty-acid--AMP ligase FadD30 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),GO:0005524; GO:0006633; GO:0016874,ATP binding; fatty acid biosynthetic process; ligase activity,PF00501;,,,,,,,,,FAA30_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),fatty acid biosynthetic process [GO:0006633] comp142569_c3_seq9,2172,46.1326,0.68126803,0,0,,4.00E-21,Q12275,Uncharacterized protein YOR093C,Uncharacterized protein YOR093C,GO:0003824; GO:0016021; GO:0005634,catalytic activity; integral to membrane; nucleus,PF00501;PF06464;,0,CHOYP_LOC100117775.1.2,,,,,,,YO093_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),metabolic process [GO:0008152] comp142570_c0_seq1,2627,27.2174,0.74049039,0,0,,1.00E-47,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp142570_c0_seq10,1248,25.9615,0.57906771,0,0,,,,,,,,,1.00E-17,CHOYP_LOC100536242.1.1,2.00E-49,ruditapes_c19911,,,,,,, comp142570_c0_seq11,3172,27.8373,0.6195483,0,0,,1.00E-62,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp142570_c0_seq12,3183,27.7725,0.62034461,0,0,,1.00E-62,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp142570_c0_seq5,2883,28.3732,0.60412372,0,0,,1.00E-48,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,2.00E-12,CHOYP_POL2.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp142570_c0_seq8,2893,28.3097,0.6047887,0,0,,,,,,,,,2.00E-17,CHOYP_LOC100536242.1.1,,,,,,,,, comp142572_c0_seq4,4947,43.6022,0.32083149,24,10,,6.00E-26,O94913,Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11),Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11),GO:0031124; GO:0006379; GO:0005849; GO:0000398; GO:0006369,"mRNA 3'-end processing; mRNA cleavage; mRNA cleavage factor complex; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription",PF04818;,,,,,,,,,PCF11_HUMAN,Homo sapiens (Human),"mRNA 3'-end processing [GO:0031124]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; termination of RNA polymerase II transcription [GO:0006369]" comp142575_c0_seq1,5702,46.0014,0.51789019,40,37,,0,O95248,Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1),Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1),GO:0017112; GO:0008219; GO:0016021; GO:0005634; GO:0005543; GO:0006470; GO:0008138; GO:0007283,Rab guanyl-nucleotide exchange factor activity; cell death; integral to membrane; nucleus; phospholipid binding; protein dephosphorylation; protein tyrosine/serine/threonine phosphatase activity; spermatogenesis,PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;,,,,,,,,,MTMR5_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283] comp142575_c0_seq3,4189,46.3356,0.4684735,8,26,,1.00E-39,Q13615,Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10),"Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)",GO:0005829; GO:0016020; GO:0046872; GO:0005634; GO:0006661; GO:0046856; GO:0004438; GO:0004722; GO:0004725; GO:0044281,cytosol; membrane; metal ion binding; nucleus; phosphatidylinositol biosynthetic process; phosphatidylinositol dephosphorylation; phosphatidylinositol-3-phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; small molecule metabolic process,PF01363;PF06602;,0,CHOYP_LOC100745865.1.1,,,,,,,MTMR3_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785] comp142575_c0_seq4,1730,44.5087,0.61898196,0,0,,0,Q86WG5,Myotubularin-related protein 13 (SET-binding factor 2),Myotubularin-related protein 13 (SET-binding factor 2),GO:0017112; GO:0016020; GO:0042552; GO:0016791; GO:0019208; GO:0035091; GO:0051262; GO:0005774,Rab guanyl-nucleotide exchange factor activity; membrane; myelination; phosphatase activity; phosphatase regulator activity; phosphatidylinositol binding; protein tetramerization; vacuolar membrane,PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;,2.00E-154,CHOYP_LOC100645183.1.1,,,,,,,MTMRD_HUMAN,Homo sapiens (Human),myelination [GO:0042552]; protein tetramerization [GO:0051262] comp142575_c0_seq5,283,45.9364,0.34424672,0,0,,2.00E-08,Q6PDH0,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),GO:0005543,phospholipid binding,PF00169;,,,,,,,,,PHLB1_MOUSE,Mus musculus (Mouse),positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507] comp142575_c0_seq6,1510,44.5695,0.62734785,0,0,,3.00E-15,Q6IQ26,DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1),DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1),GO:0005794; GO:0017112; GO:0016020,Golgi apparatus; Rab guanyl-nucleotide exchange factor activity; membrane,PF03455;PF02141;PF01477;PF02759;PF03456;,,,,,,,,,DEN5A_HUMAN,Homo sapiens (Human),"detection of mechanical stimulus [GO:0050982]; retrograde transport, endosome to Golgi [GO:0042147]" comp142581_c0_seq1,1566,44.4444,1.099922,2,0,,8.00E-24,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp142581_c0_seq3,1542,44.358,1.10822158,3,0,,,,,,,,,,,7.00E-107,ruditapes_c18442,,,,,,, comp142585_c0_seq1,1593,39.3597,0.55819245,0,873,,2.00E-15,Q2YDG0,G-protein coupled receptor family C group 5 member C,G-protein coupled receptor family C group 5 member C,GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00003;,1.00E-48,CHOYP_LOC100374272.5.6,,,,,,,GPC5C_BOVIN,Bos taurus (Bovine), comp142585_c2_seq1,1068,30.3371,0.53052156,75,702,,,,,,,,,,,2.00E-11,ruditapes_c8275,,,,,,, comp142586_c0_seq1,2615,42.8681,0.47043719,1218,4451,,3.00E-155,Q5ZIW2,CCR4-NOT transcription complex subunit 10,CCR4-NOT transcription complex subunit 10,GO:0030014; GO:0005737; GO:0031047; GO:0005634; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; cytoplasm; gene silencing by RNA; nucleus; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF13181;,4.00E-159,CHOYP_BRAFLDRAFT_118793.1.1,,,,,,,CNOTA_CHICK,Gallus gallus (Chicken),"gene silencing by RNA [GO:0031047]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]" comp142588_c0_seq3,3242,42.6897,0.50388004,87,37,,1.00E-56,Q4KMD7,Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52),Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52),GO:0005524; GO:0050265; GO:0003730; GO:0006379; GO:0006378; GO:0046872; GO:0016607; GO:0005730; GO:0004652; GO:0016180,ATP binding; RNA uridylyltransferase activity; mRNA 3'-UTR binding; mRNA cleavage; mRNA polyadenylation; metal ion binding; nuclear speck; nucleolus; polynucleotide adenylyltransferase activity; snRNA processing,PF03828;PF00076;,3.00E-17,CHOYP_LOC100375897.1.2,,,,,,,STPAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; snRNA processing [GO:0016180] comp142588_c0_seq7,665,50.5263,0.37099014,4,8,,,,,,,,,5.00E-18,CHOYP_LOC100375897.1.2,,,,,,,,, comp142589_c0_seq1,2451,39.0453,0.57450298,5,71,,2.00E-159,Q9Y6N5,"Sulfide:quinone oxidoreductase, mitochondrial (EC 1.-.-.-)","Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.-)",GO:0034641; GO:0005743; GO:0070221; GO:0070224; GO:0000098,"cellular nitrogen compound metabolic process; mitochondrial inner membrane; sulfide oxidation, using sulfide:quinone oxidoreductase; sulfide:quinone oxidoreductase activity; sulfur amino acid catabolic process",PF07992;,2.00E-24,CHOYP_BRAFLDRAFT_81609.1.1,,,,,,,SQRD_HUMAN,Homo sapiens (Human),"hydrogen sulfide metabolic process [GO:0070813]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" comp142589_c0_seq2,2436,39.1215,0.59650655,0,0,,3.00E-158,Q9Y6N5,"Sulfide:quinone oxidoreductase, mitochondrial (EC 1.-.-.-)","Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.-)",GO:0034641; GO:0005743; GO:0070221; GO:0070224; GO:0000098,"cellular nitrogen compound metabolic process; mitochondrial inner membrane; sulfide oxidation, using sulfide:quinone oxidoreductase; sulfide:quinone oxidoreductase activity; sulfur amino acid catabolic process",PF07992;,,,,,,,,,SQRD_HUMAN,Homo sapiens (Human),"hydrogen sulfide metabolic process [GO:0070813]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" comp142589_c0_seq6,2447,39.0682,0.59606089,4,23,,,,,,,,,3.00E-28,CHOYP_BRAFLDRAFT_81609.1.1,4.00E-30,ruditapes_c14027,,,,,,, comp142591_c0_seq3,1904,33.5084,0.38133568,0,0,,1.00E-53,Q6DGQ0,Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit),Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit),GO:0032044; GO:0032786; GO:0006351; GO:0008270,"DSIF complex; positive regulation of DNA-dependent transcription, elongation; transcription, DNA-dependent; zinc ion binding",PF06093;,,,,,,,,,SPT4H_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription, DNA-templated [GO:0006351]" comp142591_c0_seq5,1801,34.2032,0.46371605,0,0,,7.00E-54,Q6DGQ0,Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit),Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit),GO:0032044; GO:0032786; GO:0006351; GO:0008270,"DSIF complex; positive regulation of DNA-dependent transcription, elongation; transcription, DNA-dependent; zinc ion binding",PF06093;,3.00E-51,CHOYP_SPT4H.1.1,3.00E-62,ruditapes2_c844,,,,,SPT4H_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription, DNA-templated [GO:0006351]" comp142593_c0_seq1,1311,41.4188,0.30333215,111,317,,7.00E-07,Q86CS2,Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1),Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1),GO:0005524; GO:0048102; GO:0006995; GO:0005737; GO:0016236; GO:0070265; GO:0034045; GO:0046777; GO:0004674; GO:0015031; GO:0031288; GO:0030435,ATP binding; autophagic cell death; cellular response to nitrogen starvation; cytoplasm; macroautophagy; necrotic cell death; pre-autophagosomal structure membrane; protein autophosphorylation; protein serine/threonine kinase activity; protein transport; sorocarp morphogenesis; sporulation resulting in formation of a cellular spore,PF12063;PF00069;,,,,,,,,,ATG1_DICDI,Dictyostelium discoideum (Slime mold),autophagic cell death [GO:0048102]; cellular response to nitrogen starvation [GO:0006995]; defense response to bacterium [GO:0042742]; exit from host cell [GO:0035891]; macroautophagy [GO:0016236]; necrotic cell death [GO:0070265]; protein autophosphorylation [GO:0046777]; protein transport [GO:0015031]; response to bacterium [GO:0009617]; sorocarp development [GO:0030587]; sorocarp morphogenesis [GO:0031288]; sporulation resulting in formation of a cellular spore [GO:0030435] comp142594_c0_seq1,2495,38.2766,0.5020652,642,1923,,6.00E-165,P20664,DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49),DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49),GO:0003896; GO:0046872; GO:1990077,DNA primase activity; metal ion binding; primosome complex,PF01896;,4.00E-146,CHOYP_LOC586401.2.2,,,1.00E-114,AM861427.p.cg.6,8,,PRI1_MOUSE,Mus musculus (Mouse), comp142600_c0_seq1,536,38.2463,0.41244383,124,1302,,3.00E-13,P0C7U1,Putative inactive neutral ceramidase B (ASAH2-like protein) (Putative inactive N-acylsphingosine amidohydrolase 2B) (Putative inactive non-lysosomal ceramidase B),Putative inactive neutral ceramidase B (ASAH2-like protein) (Putative inactive N-acylsphingosine amidohydrolase 2B) (Putative inactive non-lysosomal ceramidase B),,,PF17048;,,,,,,,,,ASA2B_HUMAN,Homo sapiens (Human), comp142600_c1_seq1,1274,45.2119,0.21521595,0,0,,5.00E-118,Q55G11,Neutral ceramidase B (N-CDase B) (NCDase B) (EC 3.5.1.23) (Acylsphingosine deacylase 2B) (N-acylsphingosine amidohydrolase 2B),Neutral ceramidase B (N-CDase B) (NCDase B) (EC 3.5.1.23) (Acylsphingosine deacylase 2B) (N-acylsphingosine amidohydrolase 2B),GO:0017040; GO:0006672; GO:0005576,ceramidase activity; ceramide metabolic process; extracellular region,PF04734;PF17048;,,,,,,,,,NCSEB_DICDI,Dictyostelium discoideum (Slime mold),ceramide metabolic process [GO:0006672] comp142600_c1_seq2,1398,45.2074,0.25222369,0,0,,2.00E-159,Q304B9,Neutral ceramidase (N-CDase) (NCDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase),Neutral ceramidase (N-CDase) (NCDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase),GO:0017040; GO:0005576; GO:0006665,ceramidase activity; extracellular region; sphingolipid metabolic process,PF04734;PF17048;,,,1.00E-64,ruditapes_c27188,,,,,NCASE_ARATH,Arabidopsis thaliana (Mouse-ear cress),sphingolipid metabolic process [GO:0006665] comp142600_c1_seq3,1762,44.7787,0.28328029,7,62,,0,Q55G11,Neutral ceramidase B (N-CDase B) (NCDase B) (EC 3.5.1.23) (Acylsphingosine deacylase 2B) (N-acylsphingosine amidohydrolase 2B),Neutral ceramidase B (N-CDase B) (NCDase B) (EC 3.5.1.23) (Acylsphingosine deacylase 2B) (N-acylsphingosine amidohydrolase 2B),GO:0017040; GO:0006672; GO:0005576,ceramidase activity; ceramide metabolic process; extracellular region,PF04734;PF17048;,0,CHOYP_TRIADDRAFT_29967.1.1,,,,,,,NCSEB_DICDI,Dictyostelium discoideum (Slime mold),ceramide metabolic process [GO:0006672] comp142602_c0_seq1,651,39.9386,0.42866636,0,0,,4.00E-42,Q8BXR5,Sodium leak channel non-selective protein (Voltage gated channel-like protein 1),Sodium leak channel non-selective protein (Voltage gated channel-like protein 1),GO:0016021; GO:0005272; GO:0035725; GO:0005244,integral to membrane; sodium channel activity; sodium ion transmembrane transport; voltage-gated ion channel activity,PF00520;,,,,,,,,,NALCN_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010] comp142602_c0_seq2,1933,45.1112,0.49360095,0,0,,8.00E-14,Q2XVR4,Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b),Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b),GO:0035725; GO:0005248; GO:0001518,sodium ion transmembrane transport; voltage-gated sodium channel activity; voltage-gated sodium channel complex,PF00520;PF06512;,0,CHOYP_LOC100883628.1.1,,,,,,,SC4AB_TETNG,Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis), comp142602_c0_seq3,1989,44.7461,0.49662849,0,0,,0,Q8BXR5,Sodium leak channel non-selective protein (Voltage gated channel-like protein 1),Sodium leak channel non-selective protein (Voltage gated channel-like protein 1),GO:0016021; GO:0005272; GO:0035725; GO:0005244,integral to membrane; sodium channel activity; sodium ion transmembrane transport; voltage-gated ion channel activity,PF00520;,,,,,,,,,NALCN_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010] comp142602_c0_seq7,429,42.8904,0.51099505,41,3,,,,,,,,,3.00E-82,CHOYP_LOC100883628.1.1,,,,,,,,, comp142602_c0_seq9,1494,44.9799,0.52117622,0,0,,2.00E-32,O14234,Calcium-channel protein cch1,Calcium-channel protein cch1,GO:0005783; GO:0005789; GO:0005887; GO:0050850; GO:0032516; GO:0005245; GO:0005891,endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; positive regulation of calcium-mediated signaling; positive regulation of phosphoprotein phosphatase activity; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF00520;,6.00E-59,CHOYP_NALCN.1.1,,,,,,,CCH1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; membrane depolarization during action potential [GO:0086010]; positive regulation of calcium-mediated signaling involved in cellular response to salt stress [GO:1901196] comp142603_c1_seq1,2954,27.3527,0.62049167,237,772,,7.00E-11,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp142603_c1_seq2,1537,39.4925,0.40152307,23,47,,1.00E-118,Q1JQC6,NAD-dependent protein deacetylase sirtuin-4 (EC 3.5.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4),"NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 3.5.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4)",GO:0003950; GO:0070403; GO:0034979; GO:0006541; GO:0046872; GO:0005759; GO:0046322; GO:0046676; GO:0034983; GO:0046889; GO:0006471; GO:0006974; GO:0072350,NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent protein deacetylase activity; glutamine metabolic process; metal ion binding; mitochondrial matrix; negative regulation of fatty acid oxidation; negative regulation of insulin secretion; peptidyl-lysine deacetylation; positive regulation of lipid biosynthetic process; protein ADP-ribosylation; response to DNA damage stimulus; tricarboxylic acid metabolic process,PF02146;,5.00E-29,CHOYP_LOC100377662.1.1,,,,,,,SIR4_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; glutamine metabolic process [GO:0006541]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of insulin secretion [GO:0046676]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of lipid biosynthetic process [GO:0046889]; protein ADP-ribosylation [GO:0006471]; regulation of glutamine family amino acid metabolic process [GO:0000820]; regulation of pyruvate dehydrogenase activity [GO:1904182]; tricarboxylic acid metabolic process [GO:0072350] comp142603_c1_seq5,1649,39.2965,0.39549391,21,53,,3.00E-72,Q94AQ6,NAD-dependent protein deacetylase SRT2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2),NAD-dependent protein deacylase SRT2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2),GO:0070403; GO:0016787; GO:0046872; GO:0005759; GO:0005634,NAD+ binding; hydrolase activity; metal ion binding; mitochondrial matrix; nucleus,PF02146;,3.00E-13,CHOYP_LOC589067.1.1,,,,,,,SIR4_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ADP-ribosylation [GO:0006471] comp142605_c0_seq1,2060,40.7282,0.594188,11,0,,3.00E-152,Q9SEX2,Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (CAD ATPase) (Katanin-1) (Atp60) (Protein BOTERO 1) (Protein ECTOPIC ROOT HAIR 3) (Protein FAT ROOT) (Protein FRAGILE FIBER 2) (AtAAA1) (p60 katanin),Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (CAD ATPase) (Katanin-1) (Atp60) (Protein BOTERO 1) (Protein ECTOPIC ROOT HAIR 3) (Protein FAT ROOT) (Protein FRAGILE FIBER 2) (AtAAA1) (p60 katanin),GO:0005524; GO:0043622; GO:0005737; GO:0005874; GO:0008568; GO:0009825; GO:0009832; GO:0010091,ATP binding; cortical microtubule organization; cytoplasm; microtubule; microtubule-severing ATPase activity; multidimensional cell growth; plant-type cell wall biogenesis; trichome branching,PF00004;PF09336;,,,,,,,,,KTNA1_ARATH,Arabidopsis thaliana (Mouse-ear cress),cortical microtubule organization [GO:0043622]; microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; multidimensional cell growth [GO:0009825]; plant-type cell wall biogenesis [GO:0009832]; trichome branching [GO:0010091] comp142605_c0_seq2,2351,40.4083,0.61223622,0,0,,0,O61577,Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin),Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin),GO:0005524; GO:0051301; GO:0005737; GO:0005874; GO:0005815; GO:0008568; GO:0030496; GO:0007067; GO:0000922,ATP binding; cell division; cytoplasm; microtubule; microtubule organizing center; microtubule-severing ATPase activity; midbody; mitosis; spindle pole,PF00004;PF09336;,,,,,,,,,KTNA1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067] comp142605_c0_seq3,2075,40.8193,0.5960481,18,158,,0,Q5U3S1,Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 3.6.4.3) (p60 katanin-like 1),Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 3.6.4.3) (p60 katanin-like 1),GO:0005524; GO:0005737; GO:0005874; GO:0008568,ATP binding; cytoplasm; microtubule; microtubule-severing ATPase activity,PF00004;PF09336;,1.00E-145,CHOYP_KTNA1.2.2,,,,,,,KATL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013] comp142605_c0_seq4,2366,40.448,0.60662818,11,48,,0,O61577,Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin),Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin),GO:0005524; GO:0051301; GO:0005737; GO:0005874; GO:0005815; GO:0008568; GO:0030496; GO:0007067; GO:0000922,ATP binding; cell division; cytoplasm; microtubule; microtubule organizing center; microtubule-severing ATPase activity; midbody; mitosis; spindle pole,PF00004;PF09336;,7.00E-23,CHOYP_KATL2.2.2,,,,,,,KTNA1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067] comp142606_c0_seq1,5987,44.2626,0.44912508,425,625,,0,Q7KZ85,Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein),Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein),GO:0003677; GO:0003723; GO:0008380; GO:0006338; GO:0042393; GO:0016788; GO:0006397; GO:0051028; GO:0019048; GO:0061086; GO:0005634; GO:0032968; GO:0045191; GO:0010793; GO:0050684; GO:0051147; GO:0003700; GO:0006351,"DNA binding; RNA binding; RNA splicing; chromatin remodeling; histone binding; hydrolase activity, acting on ester bonds; mRNA processing; mRNA transport; modulation by virus of host morphology or physiology; negative regulation of histone H3-K27 methylation; nucleus; positive regulation of transcription elongation from RNA polymerase II promoter; regulation of isotype switching; regulation of mRNA export from nucleus; regulation of mRNA processing; regulation of muscle cell differentiation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF14878;PF14635;PF14641;PF00575;PF14633;PF14632;PF14639;,0,CHOYP_SPT6H.1.1,,,,,,,SPT6H_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of histone H3-K27 methylation [GO:0061086]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of isotype switching [GO:0045191]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp142606_c0_seq4,1857,46.7421,0.44337195,14,0,,5.00E-54,Q8NIV6,Transcription elongation factor spt-6 (Chromatin elongation factor spt-6),Transcription elongation factor spt-6 (Chromatin elongation factor spt-6),GO:0003677; GO:0003723; GO:0016788; GO:0005634; GO:0032784; GO:0006357; GO:0006351,"DNA binding; RNA binding; hydrolase activity, acting on ester bonds; nucleus; regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF14878;PF14635;PF14641;PF00575;PF14633;PF14632;PF14639;,,,,,,,,,SPT6_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),"regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142606_c0_seq5,286,36.7133,0.61430546,15,10,,9.00E-10,A6QQ66,Glutamate-rich protein 2,Glutamate-rich protein 2,,,,,,,,,,,,YB051_BOVIN,Bos taurus (Bovine), comp142610_c0_seq1,2134,45.1265,0.89396117,370,13955,,7.00E-172,Q9FKK7,Xylose isomerase (EC 5.3.1.5),Xylose isomerase (EC 5.3.1.5),GO:0042732; GO:0005794; GO:0005783; GO:0046872; GO:0006098; GO:0005774; GO:0009045,D-xylose metabolic process; Golgi apparatus; endoplasmic reticulum; metal ion binding; pentose-phosphate shunt; vacuolar membrane; xylose isomerase activity,,6.00E-169,CHOYP_LOC100632370.1.1,1.00E-93,ruditapes2_c184,,,,,XYLA_ARATH,Arabidopsis thaliana (Mouse-ear cress),D-xylose metabolic process [GO:0042732]; pentose-phosphate shunt [GO:0006098] comp142611_c1_seq1,2652,42.006,0.72704158,375,858,,2.00E-76,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,1.00E-140,CHOYP_PHUM_PHUM226120.7.7,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp142612_c1_seq2,1460,42.7397,0.53199705,130,248,,4.00E-84,O45933,Nucleoporin SEH1 (CeSeh1) (Nuclear pore complex protein 18) (SEC13-like protein),Nucleoporin SEH1 (CeSeh1) (Nuclear pore complex protein 18) (SEC13-like protein),GO:0051028; GO:0005643; GO:0015031,mRNA transport; nuclear pore; protein transport,PF00400;,1.00E-92,CHOYP_SEH1.1.1,,,,,,,SEH1_CAEEL,Caenorhabditis elegans,mRNA transport [GO:0051028]; protein transport [GO:0015031] comp142612_c1_seq3,358,44.6927,0.55033644,5,5,,2.00E-06,A7TLU2,Probable cytosolic iron-sulfur protein assembly protein 1,Probable cytosolic iron-sulfur protein assembly protein 1,GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,,,,,,,,,CIAO1_VANPO,Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus),iron-sulfur cluster assembly [GO:0016226]; ribosomal large subunit export from nucleus [GO:0000055]; tRNA wobble uridine modification [GO:0002098] comp142612_c1_seq4,1246,44.1413,0.48517526,47,25,,3.00E-175,A7YY75,Nucleoporin SEH1 (Nup107-160 subcomplex subunit SEH1),Nucleoporin SEH1 (Nup107-160 subcomplex subunit SEH1),GO:0051315; GO:0051301; GO:0000777; GO:0051028; GO:0007080; GO:0006999; GO:0031080; GO:0015031,attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; cell division; condensed chromosome kinetochore; mRNA transport; mitotic metaphase plate congression; nuclear pore organization; nuclear pore outer ring; protein transport,PF00400;,1.00E-92,CHOYP_SEH1.1.1,1.00E-27,ruditapes_c19689,,,,,SEH1_BOVIN,Bos taurus (Bovine),attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; cellular protein complex localization [GO:0034629]; cellular response to amino acid starvation [GO:0034198]; cytokine production involved in inflammatory response [GO:0002534]; defense response to Gram-positive bacterium [GO:0050830]; mitotic metaphase plate congression [GO:0007080]; mRNA transport [GO:0051028]; nuclear pore organization [GO:0006999]; positive regulation of TOR signaling [GO:0032008]; protein transport [GO:0015031] comp142613_c1_seq2,1045,45.8373,0.67887853,12,10,,4.00E-48,O88450,Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin),Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin),GO:0003677; GO:0048706; GO:0005576; GO:0046872; GO:0001843; GO:0005634; GO:0045944; GO:0033599; GO:0006351,"DNA binding; embryonic skeletal system development; extracellular region; metal ion binding; neural tube closure; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of mammary gland epithelial cell proliferation; transcription, DNA-dependent",PF01342;PF01753;,2.00E-62,CHOYP_BRAFLDRAFT_75725.1.1,,,,,,,DEAF1_RAT,Rattus norvegicus (Rat),"embryonic skeletal system development [GO:0048706]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of multicellular organismal development [GO:2000026]; transcription, DNA-templated [GO:0006351]" comp142613_c1_seq3,939,46.2194,0.70258824,0,0,,1.00E-06,Q9N1Q5,Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa) (Fragment),Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa) (Fragment),GO:0003677; GO:0016605; GO:0005737; GO:0010596; GO:0046826; GO:1902044; GO:0045765; GO:1902041; GO:0006355; GO:0000723; GO:0006351,"DNA binding; PML body; cytoplasm; negative regulation of endothelial cell migration; negative regulation of protein export from nucleus; regulation of Fas signaling pathway; regulation of angiogenesis; regulation of extrinsic apoptotic signaling pathway via death domain receptors; regulation of transcription, DNA-dependent; telomere maintenance; transcription, DNA-dependent",PF00505;PF09011;PF01342;,,,,,,,,,SP100_HYLLA,Hylobates lar (Common gibbon) (White-handed gibbon),"inflammatory response [GO:0006954]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of protein export from nucleus [GO:0046826]; regulation of angiogenesis [GO:0045765]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Fas signaling pathway [GO:1902044]; regulation of transcription, DNA-templated [GO:0006355]; telomere maintenance [GO:0000723]; transcription, DNA-templated [GO:0006351]" comp142614_c1_seq2,1944,43.2613,0.40849758,17,64,,0,O19015,Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),GO:0004565; GO:0005975; GO:0005764,beta-galactosidase activity; carbohydrate metabolic process; lysosome,PF13364;PF01301;,,,,,,,,,BGAL_FELCA,Felis catus (Cat) (Felis silvestris catus),carbohydrate metabolic process [GO:0005975] comp142614_c1_seq3,1788,43.0649,0.4121004,2,50,,7.00E-179,O19015,Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),GO:0004565; GO:0005975; GO:0005764,beta-galactosidase activity; carbohydrate metabolic process; lysosome,PF13364;PF01301;,4.00E-24,CHOYP_BGAL.2.2,,,,,,,BGAL_FELCA,Felis catus (Cat) (Felis silvestris catus),carbohydrate metabolic process [GO:0005975] comp142614_c1_seq5,334,44.6108,0.54442525,1,8,,6.00E-26,Q9SCV9,Beta-galactosidase 3 (Lactase 3) (EC 3.2.1.23),Beta-galactosidase 3 (Lactase 3) (EC 3.2.1.23),GO:0048046; GO:0004565; GO:0030246; GO:0005975,apoplast; beta-galactosidase activity; carbohydrate binding; carbohydrate metabolic process,PF02140;PF01301;,,,,,,,,,BGAL3_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975] comp142615_c0_seq1,2464,37.3377,0.87001121,36,58,,7.00E-10,Q9P2K6,Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5),Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5),GO:0031463; GO:0051301; GO:0005737; GO:0007067; GO:0043161; GO:0000209; GO:0032886; GO:0005819,Cul3-RING ubiquitin ligase complex; cell division; cytoplasm; mitosis; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of microtubule-based process; spindle,PF07707;PF01344;,,,,,,,,,KLDC5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of microtubule-based process [GO:0032886] comp142615_c0_seq2,2446,37.408,0.8733976,64,127,,2.00E-65,Q6TFL4,Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1),Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1),GO:0030424; GO:0005737; GO:0043204,axon; cytoplasm; perikaryon,PF07707;PF00651;PF01344;,,,,,,,,,KLH24_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; regulation of kainate selective glutamate receptor activity [GO:2000312] comp142617_c2_seq1,1175,37.1064,0.59843565,208,1798,,9.00E-18,Q3ZC71,Dolichol-phosphate mannosyltransferase subunit 3 (DPM synthase complex subunit 3) (Dolichol-phosphate mannose synthase subunit 3) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 3) (Mannose-P-dolichol synthase subunit 3) (MPD synthase subunit 3),Dolichol-phosphate mannosyltransferase subunit 3 (Dolichol-phosphate mannose synthase subunit 3) (DPM synthase subunit 3) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 3) (Mannose-P-dolichol synthase subunit 3) (MPD synthase subunit 3),GO:0006506; GO:0033185; GO:0004582; GO:0030176; GO:0031647,GPI anchor biosynthetic process; dolichol-phosphate-mannose synthase complex; dolichyl-phosphate beta-D-mannosyltransferase activity; integral to endoplasmic reticulum membrane; regulation of protein stability,PF08285;,,,,,,,,,DPM3_BOVIN,Bos taurus (Bovine),GPI anchor biosynthetic process [GO:0006506]; protein O-linked mannosylation [GO:0035269]; regulation of protein stability [GO:0031647] comp142619_c0_seq1,4028,34.3098,0.609581,0,0,,3.00E-44,Q9BZ19,Ankyrin repeat domain-containing protein 60,Ankyrin repeat domain-containing protein 60,,,PF12796;,1.00E-105,CHOYP_LOC100374676.1.1,,,,,,,ANR60_HUMAN,Homo sapiens (Human), comp142619_c0_seq2,4029,34.3261,0.61735627,0,0,,1.00E-11,Q59H18,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004672; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein kinase activity; protein serine/threonine kinase activity,PF12796;PF07714;,,,,,,,,,TNI3K_HUMAN,Homo sapiens (Human),bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027] comp142619_c0_seq3,4061,34.3265,0.60453429,0,0,,1.00E-11,Q5RF15,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF12796;PF07714;,,,,,,,,,TNI3K_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp142619_c0_seq4,4015,34.3213,0.61105667,0,0,,3.00E-44,Q9BZ19,Ankyrin repeat domain-containing protein 60,Ankyrin repeat domain-containing protein 60,,,PF12796;,1.00E-105,CHOYP_LOC100374676.1.1,,,,,,,ANR60_HUMAN,Homo sapiens (Human), comp142619_c0_seq5,4076,34.3229,0.61095833,0,0,,1.00E-11,Q59H18,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004672; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein kinase activity; protein serine/threonine kinase activity,PF12796;PF07714;,,,,,,,,,TNI3K_HUMAN,Homo sapiens (Human),bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027] comp142619_c0_seq6,4043,34.3062,0.61602608,0,0,,1.00E-11,Q5RF15,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF12796;PF07714;,1.00E-105,CHOYP_LOC100374676.1.1,,,,,,,TNI3K_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp142619_c0_seq7,4048,34.3379,0.60597523,0,0,,3.00E-44,Q9BZ19,Ankyrin repeat domain-containing protein 60,Ankyrin repeat domain-containing protein 60,,,PF12796;,,,,,,,,,ANR60_HUMAN,Homo sapiens (Human), comp142619_c0_seq8,4063,34.3342,0.61240704,0,0,,2.00E-44,Q9BZ19,Ankyrin repeat domain-containing protein 60,Ankyrin repeat domain-containing protein 60,,,PF12796;,1.00E-105,CHOYP_LOC100374676.1.1,,,3.00E-81,CU994336.p.cg.6,5,,ANR60_HUMAN,Homo sapiens (Human), comp142622_c0_seq1,2567,42.462,0.41116841,266,1281,,0,P46063,"ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)","ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)",GO:0005524; GO:0043140; GO:0004003; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0000733; GO:0015630; GO:0005634,ATP binding; ATP-dependent 3'-5' DNA helicase activity; ATP-dependent DNA helicase activity; DNA binding; DNA recombination; DNA repair; DNA replication; DNA strand renaturation; microtubule cytoskeleton; nucleus,PF00270;PF00271;PF16124;,8.00E-149,CHOYP_NEMVEDRAFT_V1G174448.1.1,,,,,,,RECQ1_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; DNA strand renaturation [GO:0000733]; double-strand break repair via homologous recombination [GO:0000724] comp142625_c1_seq1,1383,42.5163,0.27567474,1,39,,,,,,,,,6.00E-40,CHOYP_LOC100368659.2.2,,,,,,,,, comp142625_c1_seq2,1941,39.4127,0.31185687,86,461,,4.00E-108,P78316,Nucleolar protein 14 (Nucleolar complex protein 14),Nucleolar protein 14 (Nucleolar complex protein 14),GO:0030692; GO:0000480; GO:0000447; GO:0000472; GO:0005739; GO:0005730; GO:0032040; GO:0030515,"Noc4p-Nop14p complex; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mitochondrion; nucleolus; small-subunit processome; snoRNA binding",PF04147;,5.00E-43,CHOYP_LOC100368659.1.2,4.00E-23,ruditapes_c24182,,,,,NOP14_HUMAN,Homo sapiens (Human),"endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]" comp142626_c0_seq1,2854,41.0301,0.45841635,194,2735,,2.00E-134,Q9UBK8,Methionine synthase reductase (MSR) (EC 1.16.1.8),Methionine synthase reductase (MSR) (EC 1.16.1.8),GO:0010181; GO:0050661; GO:0030586; GO:0034641; GO:0009235; GO:0005829; GO:0050660; GO:0045111; GO:0005506; GO:0009086; GO:0006555; GO:0032259; GO:0005634; GO:0016709; GO:0006805,"FMN binding; NADP binding; [methionine synthase] reductase activity; cellular nitrogen compound metabolic process; cobalamin metabolic process; cytosol; flavin adenine dinucleotide binding; intermediate filament cytoskeleton; iron ion binding; methionine biosynthetic process; methionine metabolic process; methylation; nucleus; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; xenobiotic metabolic process",PF00667;PF00258;PF00175;,1.00E-27,CHOYP_LOC100371498.1.1,1.00E-25,ruditapes_c27504,,,,,MTRR_HUMAN,Homo sapiens (Human),cobalamin metabolic process [GO:0009235]; DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; methylation [GO:0032259]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; oxidation-reduction process [GO:0055114]; S-adenosylmethionine cycle [GO:0033353]; sulfur amino acid metabolic process [GO:0000096] comp142628_c0_seq1,1741,36.3584,0.59151123,0,0,,,,,,,,,2.00E-168,CHOYP_VA0D1.1.2,,,,,,,,, comp142628_c0_seq3,2200,35.8182,0.51381226,0,0,,6.00E-163,Q9W4P5,V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (V-ATPase 39 kDa subunit) (Vacuolar H+ ATPase subunit AC39-1) (Vacuolar proton pump subunit d 1),V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (V-ATPase 39 kDa subunit) (Vacuolar H+ ATPase subunit AC39-1) (Vacuolar proton pump subunit d 1),GO:0015991; GO:0033181; GO:0046961; GO:0008593; GO:0007035; GO:0000220,"ATP hydrolysis coupled proton transport; plasma membrane proton-transporting V-type ATPase complex; proton-transporting ATPase activity, rotational mechanism; regulation of Notch signaling pathway; vacuolar acidification; vacuolar proton-transporting V-type ATPase, V0 domain",PF01992;,2.00E-168,CHOYP_VA0D1.1.2,,,,,,,VA0D1_DROME,Drosophila melanogaster (Fruit fly),"ATP hydrolysis coupled proton transport [GO:0015991]; proton transport [GO:0015992]; regulation of Notch signaling pathway [GO:0008593]; terminal branching, open tracheal system [GO:0007430]; vacuolar acidification [GO:0007035]" comp142628_c0_seq8,2201,35.7565,0.51504767,0,0,,6.00E-154,Q9W4P5,V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (V-ATPase 39 kDa subunit) (Vacuolar H+ ATPase subunit AC39-1) (Vacuolar proton pump subunit d 1),V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (V-ATPase 39 kDa subunit) (Vacuolar H+ ATPase subunit AC39-1) (Vacuolar proton pump subunit d 1),GO:0015991; GO:0033181; GO:0046961; GO:0008593; GO:0007035; GO:0000220,"ATP hydrolysis coupled proton transport; plasma membrane proton-transporting V-type ATPase complex; proton-transporting ATPase activity, rotational mechanism; regulation of Notch signaling pathway; vacuolar acidification; vacuolar proton-transporting V-type ATPase, V0 domain",PF01992;,,,,,,,,,VA0D1_DROME,Drosophila melanogaster (Fruit fly),"ATP hydrolysis coupled proton transport [GO:0015991]; proton transport [GO:0015992]; regulation of Notch signaling pathway [GO:0008593]; terminal branching, open tracheal system [GO:0007430]; vacuolar acidification [GO:0007035]" comp142629_c0_seq1,3559,38.3816,1.0672016,182468,271681,,1.00E-158,Q05187,Hemocyte protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Hemocyte transglutaminase) (TGase),Hemocyte protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Hemocyte transglutaminase) (TGase),GO:0016020; GO:0046872; GO:0018149; GO:0003810,membrane; metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,TGMH_TACTR,Tachypleus tridentatus (Japanese horseshoe crab),peptide cross-linking [GO:0018149] comp142631_c0_seq2,3090,36.4401,0.71074498,293,1358,,0,Q8WVM8,Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2),Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2),GO:0032580; GO:0017119; GO:0005798; GO:0005801; GO:0005789; GO:0005886; GO:0006892; GO:0015031; GO:0060628; GO:0001666; GO:0009636; GO:0006890; GO:0019905; GO:0006904,"Golgi cisterna membrane; Golgi transport complex; Golgi-associated vesicle; cis-Golgi network; endoplasmic reticulum membrane; plasma membrane; post-Golgi vesicle-mediated transport; protein transport; regulation of ER to Golgi vesicle-mediated transport; response to hypoxia; response to toxic substance; retrograde vesicle-mediated transport, Golgi to ER; syntaxin binding; vesicle docking involved in exocytosis",PF00995;,0,CHOYP_LOC586005.1.1,,,,,,,SCFD1_HUMAN,Homo sapiens (Human),"cell morphogenesis [GO:0000902]; COPII vesicle coating [GO:0048208]; negative regulation of autophagosome assembly [GO:1902902]; phagocytosis [GO:0006909]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of protein transport [GO:0051223]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; toxin transport [GO:1901998]; vesicle docking involved in exocytosis [GO:0006904]" comp142632_c0_seq3,1288,46.0404,0.45463778,107,242,,2.00E-70,A7RM45,Probable lysosomal cobalamin transporter,Probable lysosomal cobalamin transporter,GO:0031419; GO:0016021; GO:0005765; GO:0006810,cobalamin binding; integral to membrane; lysosomal membrane; transport,PF04791;,1.00E-60,CHOYP_LMBD1.2.2,,,,,,,LMBD1_NEMVE,Nematostella vectensis (Starlet sea anemone),transport [GO:0006810] comp142633_c0_seq1,1841,44.2694,0.4626689,138,606,,4.00E-157,Q562C7,Pumilio domain-containing protein KIAA0020 homolog,Pumilio homolog 3,GO:0003723; GO:0005730,RNA binding; nucleolus,PF08144;,7.00E-110,CHOYP_K0020.1.1,,,,,,,K0020_RAT,Rattus norvegicus (Rat),regulation of protein ADP-ribosylation [GO:0010835]; regulation of translation [GO:0006417] comp142635_c0_seq2,2468,48.0146,0.56413986,348,42,,0,Q9Y4D8,Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),GO:0005737; GO:0016021; GO:0005634; GO:0042787; GO:0004842,cytoplasm; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,0,CHOYP_RGD1309762.1.1,,,,,,,HECD4_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp142635_c0_seq3,1376,50.5814,0.37701633,45,9,,1.00E-144,Q9Y4D8,Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),GO:0005737; GO:0016021; GO:0005634; GO:0042787; GO:0004842,cytoplasm; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,2.00E-115,CHOYP_RGD1309762.1.1,,,,,,,HECD4_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp142636_c0_seq2,890,32.6966,0.58939783,2958,8020,,,,,,,,,,,6.00E-16,ruditapes_c9399,,,,,,, comp142637_c0_seq2,1587,36.862,0.57680523,5,15,,,,,,,,,2.00E-77,CHOYP_MED7.1.1,,,,,,,,, comp142637_c0_seq3,1668,36.6906,0.58926701,0,0,,1.00E-82,Q17MI0,Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7),Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF05983;,,,,,,,,,MED7_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"transcription, DNA-templated [GO:0006351]" comp142637_c0_seq6,1577,36.9055,0.59789737,0,0,,,,,,,,,2.00E-77,CHOYP_MED7.1.1,,,,,,,,, comp142637_c0_seq7,1598,36.796,0.59352078,0,28,,8.00E-83,Q17MI0,Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7),Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF05983;,,,1.00E-60,ruditapes_c26274,,,,,MED7_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"transcription, DNA-templated [GO:0006351]" comp142639_c0_seq3,2813,39.4952,0.3741415,383,2026,,5.00E-38,Q9BZE9,Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9),Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9),GO:0005829; GO:0012505; GO:0019898; GO:0042593; GO:0009898; GO:0006886; GO:0005634; GO:0048471; GO:0046324; GO:0012506,cytosol; endomembrane system; extrinsic to membrane; glucose homeostasis; internal side of plasma membrane; intracellular protein transport; nucleus; perinuclear region of cytoplasm; regulation of glucose import; vesicle membrane,PF11470;PF00789;,3.00E-40,CHOYP_NEMVEDRAFT_V1G236653.1.1,,,,,,,ASPC1_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; regulation of glucose import [GO:0046324] comp142640_c0_seq1,207,37.6812,0.29275842,5,1,,2.00E-06,Q86TJ5,Zinc finger protein 554,Zinc finger protein 554,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN554_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142641_c0_seq5,862,37.239,0.51352814,0,0,,4.00E-42,Q5ZJ24,LisH domain-containing protein FOPNL (FGFR1OP N-terminal-like protein),LisH domain-containing protein FOPNL (FGFR1OP N-terminal-like protein),GO:0034451; GO:0042384; GO:0034453; GO:0005932; GO:0031514,centriolar satellite; cilium assembly; microtubule anchoring; microtubule basal body; motile cilium,PF09398;,1.00E-34,CHOYP_FOPNL.1.1,,,,,,,FOPNL_CHICK,Gallus gallus (Chicken),cilium assembly [GO:0042384]; microtubule anchoring [GO:0034453] comp142642_c0_seq1,1647,43.5944,0.38687882,3791,17296,,0,Q3T0R7,"3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase)","3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase)",GO:0003988; GO:0006631; GO:0005743; GO:0005739; GO:1901029,acetyl-CoA C-acyltransferase activity; fatty acid metabolic process; mitochondrial inner membrane; mitochondrion; negative regulation of mitochondrial outer membrane permeabilization,PF02803;PF00108;,1.00E-157,CHOYP_ACAA2.1.1,,,,,,,THIM_BOVIN,Bos taurus (Bovine),cellular response to hypoxia [GO:0071456]; fatty acid metabolic process [GO:0006631]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029] comp142643_c0_seq1,1537,36.9551,0.94108431,4,214,female>male,6.00E-14,Q6DBY9,Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST),Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST),GO:0000139; GO:0005975; GO:0016021; GO:0045130,Golgi membrane; carbohydrate metabolic process; integral to membrane; keratan sulfotransferase activity,PF00685;,,,,,,,,,CHST1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate metabolic process [GO:0005975]; sulfur compound metabolic process [GO:0006790] comp142643_c0_seq2,1423,36.402,0.89866615,0,137,,2.00E-14,Q9QUP4,Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4) (GST4) (Intestinal N-acetylglucosamine-6-O-sulfotransferase) (I-GlcNAc6ST) (Intestinal GlcNAc-6-sulfotransferase) (mIGn6ST) (N-acetylglucosamine 6-O-sulfotransferase 3) (GlcNAc6ST-3) (Gn6st-3),Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4) (GST4) (Intestinal N-acetylglucosamine-6-O-sulfotransferase) (I-GlcNAc6ST) (Intestinal GlcNAc-6-sulfotransferase) (mIGn6ST) (N-acetylglucosamine 6-O-sulfotransferase 3) (GlcNAc6ST-3) (Gn6st-3),GO:0000139; GO:0001517; GO:0006044; GO:0005975; GO:0016021; GO:0018146,Golgi membrane; N-acetylglucosamine 6-O-sulfotransferase activity; N-acetylglucosamine metabolic process; carbohydrate metabolic process; integral to membrane; keratan sulfate biosynthetic process,PF00685;,,,,,,,,,CHST5_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] comp142652_c0_seq1,2138,29.3732,0.41226424,1,293,female>male,,,,,,,,,,3.00E-18,ruditapes_c3042,,,,,,, comp142653_c0_seq1,2413,43.5557,0.46567722,174,97,,0,Q12834,Cell division cycle protein 20 homolog (p55CDC),Cell division cycle protein 20 homolog (p55CDC),GO:0051488; GO:0031145; GO:0051301; GO:0005813; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0048471; GO:0008284; GO:0090129; GO:0031915; GO:0051437; GO:0016567; GO:0050773; GO:0040020; GO:0005819; GO:0000922,activation of anaphase-promoting complex activity; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; centrosome; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; perinuclear region of cytoplasm; positive regulation of cell proliferation; positive regulation of synapse maturation; positive regulation of synaptic plasticity; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein ubiquitination; regulation of dendrite development; regulation of meiosis; spindle; spindle pole,PF12894;PF00400;,7.00E-42,CHOYP_LOC100378644.1.2,,,,,,,CDC20_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]; sister chromatid cohesion [GO:0007062] comp142653_c0_seq2,1511,47.3197,0.50992964,25,0,,6.00E-13,O61585,Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin),GO:0051301; GO:0008352; GO:0005874; GO:0051013; GO:0007067; GO:0000922,cell division; katanin complex; microtubule; microtubule severing; mitosis; spindle pole,PF13925;PF00400;,1.00E-138,CHOYP_LOC100378644.2.2,,,,,,,KTNB1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cell division [GO:0051301]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067] comp142654_c0_seq1,1618,35.7849,0.68703196,37,335,,,,,,,,,1.00E-36,CHOYP_BRAFLDRAFT_114633.1.1,,,,,,,,, comp142654_c0_seq2,1636,35.8802,0.67499613,56,380,,1.00E-85,P79769,Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO),Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO),GO:0003723; GO:0004519; GO:0090305; GO:0005634; GO:0043565,RNA binding; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; sequence-specific DNA binding,PF01997;,,,,,,,,,TSN_CHICK,Gallus gallus (Chicken), comp142656_c1_seq1,3420,39.1228,0.7119349,0,0,,,,,,,,,,,1.00E-45,ruditapes2_c2952,,,,,,, comp142656_c1_seq11,1557,39.4348,0.71109112,0,0,,,,,,,,,2.00E-33,CHOYP_APLP.2.2,,,,,,,,, comp142656_c1_seq4,4018,41.6127,0.67305483,0,0,,1.00E-119,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,3.00E-94,CHOYP_APLP.1.2,2.00E-36,ruditapes_c17599,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp142656_c1_seq5,4072,41.724,0.67183276,0,0,,2.00E-120,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,,,,,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp142656_c1_seq7,5935,40.8256,0.68809487,1,4,,2.00E-87,Q25490,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF06448;PF09172;PF01347;PF00094;,4.00E-94,CHOYP_APLP.1.2,,,,,,,APLP_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),Wnt signaling pathway [GO:0016055] comp142656_c1_seq8,5882,40.7344,0.68516322,0,0,,4.00E-99,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,,,,,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp142656_c1_seq9,1722,42.0441,0.61808613,0,0,,,,,,,,,8.00E-14,CHOYP_APLP.2.2,5.00E-52,ruditapes_c16240,,,,,,, comp142657_c2_seq1,2853,33.4034,0.45564372,1280,3061,,6.00E-92,Q61166,Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1),Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1),GO:0005794; GO:0051301; GO:0031253; GO:0005813; GO:0030981; GO:0005881; GO:0035371; GO:0051010; GO:0007067; GO:0031115; GO:0035372; GO:0005819,Golgi apparatus; cell division; cell projection membrane; centrosome; cortical microtubule cytoskeleton; cytoplasmic microtubule; microtubule plus end; microtubule plus-end binding; mitosis; negative regulation of microtubule polymerization; protein localization to microtubule; spindle,PF00307;PF03271;,4.00E-71,CHOYP_MARE3.1.1,,,2.00E-71,AM859447.p.cg.6,6,,MARE1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of microtubule plus-end binding [GO:1903033]; protein localization to microtubule [GO:0035372] comp142658_c1_seq1,1503,43.7126,0.53038369,0,0,,1.00E-17,Q6NZK5,Uncharacterized protein KIAA1328,Protein hinderin,,,PF15369;,,,,,,,,,K1328_MOUSE,Mus musculus (Mouse), comp142658_c1_seq8,1582,43.9317,0.57901498,0,0,,2.00E-17,Q6NZK5,Uncharacterized protein KIAA1328,Protein hinderin,,,PF15369;,,,,,,,,,K1328_MOUSE,Mus musculus (Mouse), comp142659_c0_seq1,1116,43.638,0.33999621,0,0,,1.00E-66,B4KLY7,Serrate RNA effector molecule homolog (Arsenite-resistance protein 2 homolog),Serrate RNA effector molecule homolog (Arsenite-resistance protein 2 homolog),GO:0016246; GO:0005654; GO:0031053,RNA interference; nucleoplasm; primary miRNA processing,PF04959;PF12066;,,,,,,,,,SRRT_DROMO,Drosophila mojavensis (Fruit fly),primary miRNA processing [GO:0031053]; RNA interference [GO:0016246] comp142659_c0_seq2,2926,43.7799,0.4315815,464,1683,,7.00E-137,Q17FR9,Serrate RNA effector molecule homolog (Arsenite-resistance protein 2 homolog),Serrate RNA effector molecule homolog (Arsenite-resistance protein 2 homolog),GO:0005654; GO:0031053,nucleoplasm; primary miRNA processing,PF04959;PF12066;,3.00E-143,CHOYP_ISCW_ISCW011341.1.1,,,,,,,SRRT_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),primary miRNA processing [GO:0031053] comp142660_c0_seq5,223,35.8744,0.2807074,2,7,,,,,,,,,,,2.00E-15,ruditapes_c20584,,,,,,, comp142664_c0_seq3,862,49.652,0.41515844,16,0,,6.00E-07,P34643,Uncharacterized protein ZK512.5,Protein transport protein Sec16 (Secretory cargo traffic protein 16),GO:0048208; GO:0070971; GO:0032527; GO:0070973,COPII vesicle coating; endoplasmic reticulum exit site; protein exit from endoplasmic reticulum; protein localization to endoplasmic reticulum exit site,PF12932;PF12931;,,,,,,,,,YOQ5_CAEEL,Caenorhabditis elegans,COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein localization to endoplasmic reticulum exit site [GO:0070973] comp142664_c0_seq7,824,49.7573,0.43313351,8,23,,5.00E-07,P34643,Uncharacterized protein ZK512.5,Protein transport protein Sec16 (Secretory cargo traffic protein 16),GO:0048208; GO:0070971; GO:0032527; GO:0070973,COPII vesicle coating; endoplasmic reticulum exit site; protein exit from endoplasmic reticulum; protein localization to endoplasmic reticulum exit site,PF12932;PF12931;,,,,,,,,,YOQ5_CAEEL,Caenorhabditis elegans,COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein localization to endoplasmic reticulum exit site [GO:0070973] comp142665_c1_seq1,647,39.4127,0.36647065,0,0,,2.00E-21,Q63ZM9,Zinc finger protein 830 (Coiled-coil domain-containing protein 16),Zinc finger protein 830 (Coiled-coil domain-containing protein 16),GO:0051301; GO:0046872; GO:0007067; GO:0007275; GO:0005634,cell division; metal ion binding; mitosis; multicellular organismal development; nucleus,,,,,,,,,,ZN830_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275] comp142665_c1_seq4,2095,36.3723,0.43876308,5,0,,4.00E-36,Q63ZM9,Zinc finger protein 830 (Coiled-coil domain-containing protein 16),Zinc finger protein 830 (Coiled-coil domain-containing protein 16),GO:0051301; GO:0046872; GO:0007067; GO:0007275; GO:0005634,cell division; metal ion binding; mitosis; multicellular organismal development; nucleus,,5.00E-43,CHOYP_LOC583668.1.1,,,,,,,ZN830_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275] comp142665_c1_seq6,1512,34.7222,0.48730733,8,40,,,,,,,,,3.00E-19,CHOYP_LOC583668.1.1,,,,,,,,, comp142670_c0_seq1,973,40.4933,0.22899711,223,863,,2.00E-116,Q9D554,Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61),Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61),GO:0008380; GO:0071013; GO:0006397; GO:0003676; GO:0008270,RNA splicing; catalytic step 2 spliceosome; mRNA processing; nucleic acid binding; zinc ion binding,PF11931;PF16837;PF12108;,2.00E-145,CHOYP_SF3A3.1.1,,,,,,,SF3A3_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]" comp142670_c1_seq1,2258,36.8025,0.33794185,323,1427,,7.00E-37,O59706,Pre-mRNA-splicing factor sap61 (Spliceosome-associated protein 61),Pre-mRNA-splicing factor sap61 (Spliceosome-associated protein 61),GO:0003723; GO:0005686; GO:0005829; GO:0045292; GO:0005681; GO:0008270,"RNA binding; U2 snRNP; cytosol; mRNA cis splicing, via spliceosome; spliceosomal complex; zinc ion binding",PF11931;PF16837;PF12108;PF12171;,,,,,,,,,SAP61_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]" comp142670_c1_seq2,1531,34.8792,0.53298566,180,836,,5.00E-90,O46106,Splicing factor 3A subunit 3 (Protein noisette),Splicing factor 3A subunit 3 (Protein noisette),GO:0005686; GO:0071013; GO:0009566; GO:0000398; GO:0007067; GO:0007052; GO:0003676; GO:0051533; GO:0071011; GO:0051726; GO:0008270,"U2 snRNP; catalytic step 2 spliceosome; fertilization; mRNA splicing, via spliceosome; mitosis; mitotic spindle organization; nucleic acid binding; positive regulation of NFAT protein import into nucleus; precatalytic spliceosome; regulation of cell cycle; zinc ion binding",PF11931;PF16837;PF12108;,,,,,,,,,NOI_DROME,Drosophila melanogaster (Fruit fly),"fertilization [GO:0009566]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of NFAT protein import into nucleus [GO:0051533]; regulation of cell cycle [GO:0051726]" comp142670_c2_seq1,1303,36.8381,0.67341018,82,432,,8.00E-111,O60841,Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2),Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2),GO:0005525; GO:0006184; GO:0003924; GO:0005829; GO:0006446; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; cytosol; regulation of translational initiation; translation initiation factor activity,PF03144;PF11987;,3.00E-94,CHOYP_LOC662115.2.2,,,4.00E-94,AM861996.p.cg.6,3,,IF2P_HUMAN,Homo sapiens (Human),regulation of translational initiation [GO:0006446] comp142670_c2_seq2,905,46.4088,0.47433533,97,967,,4.00E-87,Q10251,Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2),Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2),GO:0005525; GO:0006184; GO:0003924; GO:0002183; GO:0005829; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; cytoplasmic translational initiation; cytosol; translation initiation factor activity,PF03144;PF11987;,6.00E-95,CHOYP_LOC662115.2.2,,,,,,,IF2P_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translational initiation [GO:0002183]; translation [GO:0006412] comp142671_c0_seq10,641,44.7738,0.52758218,0,0,,,,,,,,,2.00E-68,CHOYP_LOC100533400.4.4,,,,,,,,, comp142671_c0_seq12,2010,35.9701,0.59687588,0,0,,6.00E-72,P36975,Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein),Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein),GO:0006893; GO:0005484; GO:0031201; GO:0030054; GO:0043005; GO:0005886; GO:0048172; GO:0045202; GO:0016081; GO:0016082,Golgi to plasma membrane transport; SNAP receptor activity; SNARE complex; cell junction; neuron projection; plasma membrane; regulation of short-term neuronal synaptic plasticity; synapse; synaptic vesicle docking involved in exocytosis; synaptic vesicle priming,PF00835;,,,,,,,,,SNP25_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; Golgi to plasma membrane transport [GO:0006893]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] comp142671_c0_seq4,2025,36,0.62238895,0,0,,2.00E-73,P36975,Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein),Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein),GO:0006893; GO:0005484; GO:0031201; GO:0030054; GO:0043005; GO:0005886; GO:0048172; GO:0045202; GO:0016081; GO:0016082,Golgi to plasma membrane transport; SNAP receptor activity; SNARE complex; cell junction; neuron projection; plasma membrane; regulation of short-term neuronal synaptic plasticity; synapse; synaptic vesicle docking involved in exocytosis; synaptic vesicle priming,PF00835;,1.00E-88,CHOYP_LOC100533400.3.4,,,,,,,SNP25_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; Golgi to plasma membrane transport [GO:0006893]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] comp142671_c0_seq9,1923,35.5174,0.60943951,0,0,,1.00E-70,P36975,Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein),Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein),GO:0006893; GO:0005484; GO:0031201; GO:0030054; GO:0043005; GO:0005886; GO:0048172; GO:0045202; GO:0016081; GO:0016082,Golgi to plasma membrane transport; SNAP receptor activity; SNARE complex; cell junction; neuron projection; plasma membrane; regulation of short-term neuronal synaptic plasticity; synapse; synaptic vesicle docking involved in exocytosis; synaptic vesicle priming,PF00835;,1.00E-93,CHOYP_LOC100533400.3.4,,,,,,,SNP25_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; Golgi to plasma membrane transport [GO:0006893]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] comp142676_c1_seq1,3061,40.0196,0.34416099,73,243,,4.00E-140,Q803U7,Exonuclease 1 (EC 3.1.-.-) (Exonuclease I),Exonuclease 1 (EC 3.1.-.-) (Exonuclease I),GO:0003677; GO:0006310; GO:0048256; GO:0046872; GO:0006298; GO:0005634; GO:0045145,DNA binding; DNA recombination; flap endonuclease activity; metal ion binding; mismatch repair; nucleus; single-stranded DNA 5'-3' exodeoxyribonuclease activity,PF00867;PF00752;,6.00E-120,CHOYP_EXO1.2.2,,,,,,,EXO1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA recombination [GO:0006310]; mismatch repair [GO:0006298] comp142676_c1_seq2,2117,39.0175,0.29818918,43,151,,1.00E-16,Q9UQ84,Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI),Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI),GO:0003677; GO:0006310; GO:0051908; GO:0048256; GO:0002455; GO:0045190; GO:0007126; GO:0046872; GO:0006298; GO:0005634; GO:0004523; GO:0045145; GO:0016446; GO:0043566,DNA binding; DNA recombination; double-stranded DNA 5'-3' exodeoxyribonuclease activity; flap endonuclease activity; humoral immune response mediated by circulating immunoglobulin; isotype switching; meiosis; metal ion binding; mismatch repair; nucleus; ribonuclease H activity; single-stranded DNA 5'-3' exodeoxyribonuclease activity; somatic hypermutation of immunoglobulin genes; structure-specific DNA binding,PF00867;PF00752;,,,,,,,,,EXO1_HUMAN,Homo sapiens (Human),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; isotype switching [GO:0045190]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; regulation of signal transduction by p53 class mediator [GO:1901796]; somatic hypermutation of immunoglobulin genes [GO:0016446]; strand displacement [GO:0000732] comp142677_c0_seq1,2267,44.464,0.48452367,177,654,,1.00E-81,Q80US4,Actin-related protein 5,Actin-related protein 5,GO:0006310; GO:0031011; GO:0070914; GO:0005737; GO:0006302; GO:0006355; GO:0006351,"DNA recombination; Ino80 complex; UV-damage excision repair; cytoplasm; double-strand break repair; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00022;,1.00E-127,CHOYP_LOC100370071.1.1,,,,,,,ARP5_MOUSE,Mus musculus (Mouse),"DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; UV-damage excision repair [GO:0070914]" comp142680_c0_seq2,3594,40.2615,0.67647855,4941,372,,6.00E-89,Q8BRC6,Protein MAATS1 (AMY-1-associating protein expressed in testis 1 homolog) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1),Protein MAATS1 (AMY-1-associating protein expressed in testis 1 homolog) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1),GO:0005739,mitochondrion,PF14738;,0,CHOYP_LOC100367205.1.1,,,,,,,AAT1_MOUSE,Mus musculus (Mouse), comp142682_c1_seq1,2531,40.3398,0.5023224,41,37,,4.00E-101,Q5R787,ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3),ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3),GO:0008060; GO:0000139; GO:0005829; GO:0043547; GO:0009306; GO:0032312; GO:0016192; GO:0008270,ARF GTPase activator activity; Golgi membrane; cytosol; positive regulation of GTPase activity; protein secretion; regulation of ARF GTPase activity; vesicle-mediated transport; zinc ion binding,PF01412;,,,,,,,,,ARFG3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192] comp142682_c1_seq2,1767,44.7651,0.51775319,0,15,,5.00E-102,Q4R4C9,ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3),ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3),GO:0008060; GO:0000139; GO:0043547; GO:0015031; GO:0032312; GO:0016192; GO:0008270,ARF GTPase activator activity; Golgi membrane; positive regulation of GTPase activity; protein transport; regulation of ARF GTPase activity; vesicle-mediated transport; zinc ion binding,PF01412;,8.00E-122,CHOYP_LOC100373141.1.1,,,,,,,ARFG3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp142682_c1_seq3,2552,40.3605,0.50742865,0,71,,7.00E-13,Q09531,Uncharacterized protein F07F6.4,Uncharacterized protein F07F6.4,GO:0008060; GO:0043547; GO:0032312; GO:0008270,ARF GTPase activator activity; positive regulation of GTPase activity; regulation of ARF GTPase activity; zinc ion binding,PF01412;,,,,,,,,,YQP4_CAEEL,Caenorhabditis elegans, comp142682_c1_seq4,2514,40.3739,0.50425776,30,225,,2.00E-116,Q99K28,ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289),ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289),GO:0008060; GO:0000139; GO:0043547; GO:0015031; GO:0032312; GO:0016192; GO:0008270,ARF GTPase activator activity; Golgi membrane; positive regulation of GTPase activity; protein transport; regulation of ARF GTPase activity; vesicle-mediated transport; zinc ion binding,PF01412;,1.00E-121,CHOYP_LOC100373141.1.1,,,,,,,ARFG2_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp142683_c1_seq1,2464,30.6818,0.45415257,233,251,,,,,,,,,2.00E-87,CHOYP_NEMVEDRAFT_V1G165338.1.1,,,,,,,,, comp142683_c1_seq3,2488,30.3457,0.51270749,460,165,,,,,,,,,1.00E-77,CHOYP_GBRAP.1.1,,,,,,,,, comp142683_c1_seq5,2386,30.2598,0.44425841,0,0,,1.00E-68,P60517,Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein),Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein),GO:0000139; GO:0015629; GO:0005776; GO:0000421; GO:0006914; GO:0044297; GO:0031410; GO:0008625; GO:0005764; GO:0005874; GO:0005875; GO:0000226; GO:0048471; GO:0005886; GO:0015031; GO:0005790,Golgi membrane; actin cytoskeleton; autophagic vacuole; autophagic vacuole membrane; autophagy; cell body; cytoplasmic vesicle; extrinsic apoptotic signaling pathway via death domain receptors; lysosome; microtubule; microtubule associated complex; microtubule cytoskeleton organization; perinuclear region of cytoplasm; plasma membrane; protein transport; smooth endoplasmic reticulum,PF02991;,2.00E-87,CHOYP_NEMVEDRAFT_V1G165338.1.1,2.00E-96,ruditapes_c7131,,,,,GBRAP_RAT,Rattus norvegicus (Rat),autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; microtubule cytoskeleton organization [GO:0000226]; mitophagy [GO:0000422]; protein transport [GO:0015031] comp142684_c0_seq2,3952,41.8269,0.35851093,3,9,,4.00E-141,O15381,Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein),Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein),GO:0005524; GO:0016235; GO:0005737; GO:0005730; GO:0017111,ATP binding; aggresome; cytoplasm; nucleolus; nucleoside-triphosphatase activity,PF00004;PF16725;,1.00E-111,CHOYP_PHUM_PHUM563970.1.1,,,,,,,NVL_HUMAN,Homo sapiens (Human),positive regulation of telomerase activity [GO:0051973]; ribosome biogenesis [GO:0042254] comp142684_c0_seq3,2960,40.3716,0.33617743,4,0,,6.00E-49,Q9C0W2,Uncharacterized AAA domain-containing protein P22H7.05c,Uncharacterized AAA domain-containing protein P22H7.05c,GO:0005524; GO:0016887; GO:0006338; GO:0000790; GO:0045944,ATP binding; ATPase activity; chromatin remodeling; nuclear chromatin; positive regulation of transcription from RNA polymerase II promoter,PF00004;,,,,,,,,,YHI5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp142684_c0_seq4,4073,41.6892,0.36160988,101,944,,6.00E-06,Q6FEP7,ATP-dependent Clp protease ATP-binding subunit ClpX,ATP-dependent Clp protease ATP-binding subunit ClpX,GO:0005524; GO:0017111; GO:0006457; GO:0008270,ATP binding; nucleoside-triphosphatase activity; protein folding; zinc ion binding,PF07724;PF10431;PF06689;,1.00E-111,CHOYP_PHUM_PHUM563970.1.1,,,,,,,CLPX_ACIAD,Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1),protein folding [GO:0006457] comp142686_c0_seq1,2508,40.311,0.89579032,387,776,,2.00E-108,Q8AX98,T-box transcription factor TBX1-A (T-box protein 1-A),T-box transcription factor TBX1-A (T-box protein 1-A),GO:0003677; GO:0071300; GO:0060788; GO:0007275; GO:0005634; GO:0045944; GO:0050793; GO:0003700; GO:0006351,"DNA binding; cellular response to retinoic acid; ectodermal placode formation; multicellular organismal development; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of developmental process; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00907;,1.00E-146,CHOYP_BRAFLDRAFT_56662.1.1,,,,,,,TBX1A_XENLA,Xenopus laevis (African clawed frog),"cellular response to retinoic acid [GO:0071300]; ectodermal placode formation [GO:0060788]; multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental process [GO:0050793]; transcription, DNA-templated [GO:0006351]" comp142688_c1_seq1,4665,40.3001,0.64987842,13,1227,,4.00E-42,Q8R508,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT3_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp142688_c1_seq6,4871,39.6223,0.63848001,12,1384,female>male,1.00E-42,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp142689_c1_seq1,351,35.6125,0.75093943,1286,1550,,,,,,,,,,,7.00E-17,ruditapes2_c1591,,,,,,, comp142691_c1_seq1,4795,37.8936,0.77969551,726,5009,,8.00E-166,Q28824,"Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]","Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]",GO:0005524; GO:0032154; GO:0005737; GO:0005856; GO:0030027; GO:0046872; GO:0004687,ATP binding; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; metal ion binding; myosin light chain kinase activity,PF00041;PF07679;PF00069;,7.00E-77,CHOYP_PHUM_PHUM226120.5.7,2.00E-11,ruditapes2_c1891,,,,,MYLK_BOVIN,Bos taurus (Bovine),positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939] comp142692_c1_seq1,1179,42.0696,0.41258771,9,5,,5.00E-64,Q5R9R1,Erythroid differentiation-related factor 1,Erythroid differentiation-related factor 1,GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,EDRF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142692_c1_seq3,1132,41.1661,0.44723719,0,0,,2.00E-58,Q5R9R1,Erythroid differentiation-related factor 1,Erythroid differentiation-related factor 1,GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,3.00E-11,CHOYP_EDRF1.2.2,,,,,,,EDRF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142692_c1_seq4,1129,40.3897,0.43921908,110,383,,6.00E-63,Q60HG0,Fukutin (EC 2.-.-.-),Fukutin (EC 2.-.-.-),GO:0000139; GO:0005801; GO:0016021; GO:0016740,Golgi membrane; cis-Golgi network; integral to membrane; transferase activity,PF04991;,2.00E-33,CHOYP_FKTN.1.1,,,,,,,FKTN_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein O-linked mannosylation [GO:0035269] comp142693_c0_seq1,2493,38.227,0.29671903,174,589,,,,,,,,,1.00E-39,CHOYP_LOC100372990.1.1,,,,,,,,, comp142693_c0_seq3,1315,45.1711,0.37308377,60,143,,1.00E-67,Q5UIP0,Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog),Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog),GO:0007049; GO:0000781; GO:0005737; GO:0001939; GO:0001940; GO:0006974; GO:0005819; GO:0019827; GO:0000723,"cell cycle; chromosome, telomeric region; cytoplasm; female pronucleus; male pronucleus; response to DNA damage stimulus; spindle; stem cell maintenance; telomere maintenance",PF12231;,3.00E-30,CHOYP_RIF1.1.1,,,,,,,RIF1_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; double-strand break repair via nonhomologous end joining [GO:0006303]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; stem cell population maintenance [GO:0019827] comp142695_c0_seq1,1923,39.6256,0.57444283,435,1139,,5.00E-118,Q52DF3,Pre-mRNA-splicing factor SYF1,Pre-mRNA-splicing factor SYF1,GO:0008380; GO:0007049; GO:0006397; GO:0005681,RNA splicing; cell cycle; mRNA processing; spliceosomal complex,,,,,,,,,,SYF1_MAGO7,Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp142695_c0_seq4,1449,42.9952,0.73744473,106,254,,0,Q9HCS7,Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2),Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2),GO:0001824; GO:0071013; GO:0000398; GO:0005654; GO:0006351; GO:0006283,"blastocyst development; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; transcription, DNA-dependent; transcription-coupled nucleotide-excision repair",PF13181;,0,CHOYP_ISCW_ISCW023297.1.1,,,,,,,SYF1_HUMAN,Homo sapiens (Human),"blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; mRNA splicing, via spliceosome [GO:0000398]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp142696_c0_seq1,3221,45.669,0.33368845,29,172,,9.00E-121,A2AKG8,Focadhesin,Focadhesin,GO:0005925; GO:0016021,focal adhesion; integral to membrane,PF11229;PF12530;,4.00E-33,CHOYP_FOCAD.2.2,,,,,,,FOCAD_MOUSE,Mus musculus (Mouse), comp142696_c0_seq2,2727,44.7745,0.29293964,30,133,,5.00E-88,A2AKG8,Focadhesin,Focadhesin,GO:0005925; GO:0016021,focal adhesion; integral to membrane,PF11229;PF12530;,,,,,,,,,FOCAD_MOUSE,Mus musculus (Mouse), comp142697_c0_seq5,2824,46.3173,0.51020654,132,100,,0,O18964,"Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) (p150) (Fragment)","Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) (p150) (Fragment)",GO:0003723; GO:0006897; GO:0000166; GO:0048471; GO:0046856; GO:0004439,"RNA binding; endocytosis; nucleotide binding; perinuclear region of cytoplasm; phosphatidylinositol dephosphorylation; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",PF08952;PF03372;PF02383;,1.00E-121,CHOYP_SYNJ1.1.1,,,,,,,SYNJ1_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; phosphatidylinositol dephosphorylation [GO:0046856] comp142699_c0_seq1,2664,46.1712,0.71870689,167,103,,2.00E-32,Q6ZP82,Coiled-coil domain-containing protein 141,Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1),,,PF00435;,0,CHOYP_TITIN.18.19,,,,,,,CC141_HUMAN,Homo sapiens (Human),centrosome localization [GO:0051642]; cerebral cortex radially oriented cell migration [GO:0021799] comp142699_c0_seq2,4168,47.2169,0.7621124,9,18,,1.00E-78,Q80UK0,SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein),SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein),GO:0034704; GO:0070300; GO:0043325; GO:0080025; GO:0032266; GO:0005546; GO:0070273; GO:0010314,"calcium channel complex; phosphatidic acid binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding",PF13716;,,,,,,,,,SESD1_MOUSE,Mus musculus (Mouse), comp142699_c0_seq5,4053,47.1996,0.77107632,0,0,,6.00E-76,Q80UK0,SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein),SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein),GO:0034704; GO:0070300; GO:0043325; GO:0080025; GO:0032266; GO:0005546; GO:0070273; GO:0010314,"calcium channel complex; phosphatidic acid binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding",PF13716;,,,,,,,,,SESD1_MOUSE,Mus musculus (Mouse), comp142699_c0_seq6,611,47.7905,1.06475105,0,0,,,,,,,,,1.00E-12,CHOYP_TITIN.18.19,,,,,,,,, comp142699_c0_seq7,1233,49.0673,0.97288838,7,0,,,,,,,,,2.00E-120,CHOYP_LOC100169177.1.1,,,,,,,,, comp142699_c1_seq2,442,48.8688,0.84785123,14,9,,7.00E-19,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp142700_c0_seq1,4274,40.0796,0.41699183,207,1672,,1.00E-14,Q659A1,NMDA receptor-regulated protein 2,Little elongation complex subunit 2 (Interactor of little elongator complex ELL subunit 2) (NMDA receptor-regulated protein 2),GO:0005634,nucleus,PF10505;,,,,,,,,,NARG2_HUMAN,Homo sapiens (Human),positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; snRNA transcription from RNA polymerase III promoter [GO:0042796]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp142701_c0_seq2,3985,42.5345,0.35764618,413,1366,,0,Q8R0G9,Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133),Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133),GO:0000940; GO:0006406; GO:0006999; GO:0031080; GO:0005487; GO:0048339; GO:0015031,condensed chromosome outer kinetochore; mRNA export from nucleus; nuclear pore organization; nuclear pore outer ring; nucleocytoplasmic transporter activity; paraxial mesoderm development; protein transport,PF03177;,2.00E-71,CHOYP_LOC100374754.1.1,,,,,,,NU133_MOUSE,Mus musculus (Mouse),"chromatin organization [GO:0006325]; mRNA export from nucleus [GO:0006406]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; nuclear pore distribution [GO:0031081]; nuclear pore organization [GO:0006999]; paraxial mesoderm development [GO:0048339]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]; RNA export from nucleus [GO:0006405]; somite development [GO:0061053]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]" comp142702_c0_seq1,1607,36.5899,0.8339859,30,451,,5.00E-07,P68638,Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP),Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP),GO:0020002; GO:0016021; GO:0039573; GO:0055036,host cell plasma membrane; integral to membrane; suppression by virus of host complement activation; virion membrane,PF00084;,,,,,,,,,VCP_VACCW,Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)),suppression by virus of host complement activation [GO:0039573] comp142704_c1_seq1,2237,35.494,0.36920156,0,0,,,,,,,,,7.00E-29,CHOYP_LOC100893922.1.1,,,,,,,,, comp142704_c1_seq9,2274,35.2243,0.3829776,0,0,,,,,,,,,7.00E-29,CHOYP_LOC100893922.1.1,,,,,,,,, comp142707_c0_seq1,2277,44.7079,0.53832864,274,1374,,9.00E-153,Q5XGY1,Pre-rRNA-processing protein TSR1 homolog,Pre-rRNA-processing protein TSR1 homolog,GO:0005730; GO:0042255,nucleolus; ribosome assembly,PF08142;PF04950;,,,,,,,,,TSR1_XENLA,Xenopus laevis (African clawed frog),ribosome assembly [GO:0042255] comp142707_c0_seq2,852,44.3662,0.43103846,15,109,,3.00E-21,O94653,Ribosome biogenesis protein bms1,Ribosome biogenesis protein bms1,GO:0005524; GO:0005525; GO:0006184; GO:0003924; GO:0005739; GO:0005730; GO:0006364; GO:0042255; GO:0005819,ATP binding; GTP binding; GTP catabolic process; GTPase activity; mitochondrion; nucleolus; rRNA processing; ribosome assembly; spindle,PF08142;PF04950;,1.00E-59,CHOYP_BRAFLDRAFT_203247.1.1,,,,,,,BMS1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]" comp142707_c1_seq1,349,38.1089,0.56818648,180,1005,,2.00E-23,Q5SWD9,Pre-rRNA-processing protein TSR1 homolog,Pre-rRNA-processing protein TSR1 homolog,GO:0005730; GO:0042255,nucleolus; ribosome assembly,PF08142;PF04950;,,,,,,,,,TSR1_MOUSE,Mus musculus (Mouse),"endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]" comp142708_c0_seq11,2116,36.9565,0.26861003,0,11,,6.00E-20,Q60352,Isopentenyl phosphate kinase (IPK) (EC 2.7.4.26),Isopentenyl phosphate kinase (IPK) (EC 2.7.4.26),GO:0005524; GO:0004349; GO:0006561,ATP binding; glutamate 5-kinase activity; proline biosynthetic process,PF00696;,,,,,,,,,Y044_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),isoprenoid biosynthetic process [GO:0008299]; proline biosynthetic process [GO:0006561] comp142708_c0_seq5,2167,36.5944,0.29604012,0,0,,6.00E-20,Q60352,Isopentenyl phosphate kinase (IPK) (EC 2.7.4.26),Isopentenyl phosphate kinase (IPK) (EC 2.7.4.26),GO:0005524; GO:0004349; GO:0006561,ATP binding; glutamate 5-kinase activity; proline biosynthetic process,PF00696;,,,,,,,,,Y044_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),isoprenoid biosynthetic process [GO:0008299]; proline biosynthetic process [GO:0006561] comp142709_c0_seq1,2774,37.6712,0.56038795,12904,27600,,1.00E-176,Q9GP32,Fructose-bisphosphate aldolase (EC 4.1.2.13),Fructose-bisphosphate aldolase (EC 4.1.2.13),GO:0004332; GO:0006096,fructose-bisphosphate aldolase activity; glycolysis,PF00274;,3.00E-180,CHOYP_ALF.2.3,7.00E-47,ruditapes2_c703,,,,,ALF_ECHMU,Echinococcus multilocularis (Fox tapeworm),glycolytic process [GO:0006096] comp142710_c0_seq1,1197,36.9256,0.64153942,182,145,,2.00E-66,A0AVK6,Transcription factor E2F8 (E2F-8),Transcription factor E2F8 (E2F-8),GO:0033301; GO:0008283; GO:0060718; GO:0001047; GO:0070365; GO:0032466; GO:0000122; GO:0005634; GO:0032877; GO:0045944; GO:0003700; GO:0002040; GO:0003714; GO:0005667; GO:0006351; GO:0060707,"cell cycle comprising mitosis without cytokinesis; cell proliferation; chorionic trophoblast cell differentiation; core promoter binding; hepatocyte differentiation; negative regulation of cytokinesis; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; sprouting angiogenesis; transcription corepressor activity; transcription factor complex; transcription, DNA-dependent; trophoblast giant cell differentiation",PF02319;,1.00E-59,CHOYP_E2F7.1.2,,,,,,,E2F8_HUMAN,Homo sapiens (Human),"cell cycle comprising mitosis without cytokinesis [GO:0033301]; cell proliferation [GO:0008283]; chorionic trophoblast cell differentiation [GO:0060718]; hepatocyte differentiation [GO:0070365]; negative regulation of cytokinesis [GO:0032466]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; placenta development [GO:0001890]; positive regulation of DNA endoreduplication [GO:0032877]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]" comp142716_c0_seq1,4684,41.076,0.89370123,0,42,,4.00E-45,C6KFA3,G-protein coupled receptor 126,G-protein coupled receptor 126,GO:0004930; GO:0016021; GO:0042552; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; myelination; neuropeptide signaling pathway; plasma membrane,PF00002;PF00431;PF01825;PF00354;,4.00E-16,CHOYP_LOC577191.1.1,,,,,,,GP126_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879] comp142716_c0_seq3,4668,41.1954,0.89620014,0,0,,4.00E-25,P48960,CD97 antigen (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: CD97 antigen subunit alpha; CD97 antigen subunit beta],CD97 antigen (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: CD97 antigen subunit alpha; CD97 antigen subunit beta],GO:0004930; GO:0005509; GO:0007155; GO:0007267; GO:0006928; GO:0005615; GO:0006955; GO:0006954; GO:0005887; GO:0007218,G-protein coupled receptor activity; calcium ion binding; cell adhesion; cell-cell signaling; cellular component movement; extracellular space; immune response; inflammatory response; integral to plasma membrane; neuropeptide signaling pathway,PF00002;PF07645;PF01825;,4.00E-16,CHOYP_LOC577191.1.1,,,,,,,CD97_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; movement of cell or subcellular component [GO:0006928] comp142716_c0_seq4,4707,41.024,0.89162065,0,0,,4.00E-45,C6KFA3,G-protein coupled receptor 126,G-protein coupled receptor 126,GO:0004930; GO:0016021; GO:0042552; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; myelination; neuropeptide signaling pathway; plasma membrane,PF00002;PF00431;PF01825;PF00354;,4.00E-16,CHOYP_LOC577191.1.1,,,,,,,GP126_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879] comp142716_c0_seq6,4645,41.1841,0.89597171,0,0,,4.00E-45,C6KFA3,G-protein coupled receptor 126,G-protein coupled receptor 126,GO:0004930; GO:0016021; GO:0042552; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; myelination; neuropeptide signaling pathway; plasma membrane,PF00002;PF00431;PF01825;PF00354;,4.00E-16,CHOYP_LOC577191.1.1,,,,,,,GP126_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879] comp142716_c0_seq8,4689,41.2028,0.90720058,0,0,,5.00E-45,C6KFA3,G-protein coupled receptor 126,G-protein coupled receptor 126,GO:0004930; GO:0016021; GO:0042552; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; myelination; neuropeptide signaling pathway; plasma membrane,PF00002;PF00431;PF01825;PF00354;,,,,,,,,,GP126_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879] comp142718_c0_seq1,3496,42.1911,0.43227485,2381,5474,,0,P56399,Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5),Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5),GO:0008234; GO:0008242; GO:0032436; GO:0071108; GO:0004221; GO:0006511; GO:0008270,cysteine-type peptidase activity; omega peptidase activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF00627;PF00443;PF02148;,0,CHOYP_LOC100377783.1.1,,,,,,,UBP5_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511] comp142722_c0_seq2,497,44.0644,0.58148692,47,387,,2.00E-51,Q32NG4,Parkinson disease 7 domain-containing protein 1,Parkinson disease 7 domain-containing protein 1,GO:0005576,extracellular region,,,,,,,,,,PDDC1_XENLA,Xenopus laevis (African clawed frog), comp142724_c1_seq2,1565,44.1534,0.5518343,124,158,,7.00E-108,Q01167,Forkhead box protein K2 (Cellular transcription factor ILF-1) (FOXK1) (Interleukin enhancer-binding factor 1),Forkhead box protein K2 (Cellular transcription factor ILF-1) (FOXK1) (Interleukin enhancer-binding factor 1),GO:0008301; GO:0009790; GO:0000287; GO:0005634; GO:0007389; GO:0006357; GO:0043565; GO:0003700; GO:0009888; GO:0006351,"DNA binding, bending; embryo development; magnesium ion binding; nucleus; pattern specification process; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tissue development; transcription, DNA-dependent",PF00498;PF00250;,2.00E-85,CHOYP_FOXK2.1.1,,,,,,,FOXK2_HUMAN,Homo sapiens (Human),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]" comp142725_c0_seq1,1437,41.6841,0.58167627,133,193,,4.00E-55,Q6DFJ9,Cyclin-J,Cyclin-J,GO:0005634,nucleus,PF02984;PF00134;,1.00E-22,CHOYP_CCNJ.1.1,,,,,,,CCNJ_XENLA,Xenopus laevis (African clawed frog), comp142726_c0_seq1,3969,40.4636,0.46918731,1302,6786,,0,Q11011,Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S),Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S),GO:0004177; GO:0005829; GO:0008237; GO:0005634; GO:0006508; GO:0008270,aminopeptidase activity; cytosol; metallopeptidase activity; nucleus; proteolysis; zinc ion binding,PF11838;PF01433;,0,CHOYP_PSA.1.1,2.00E-16,ruditapes2_c2303,,,,,PSA_MOUSE,Mus musculus (Mouse),cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; proteolysis [GO:0006508] comp142729_c0_seq6,1931,33.4024,0.67559027,39,154,,9.00E-37,B4QX46,Mesencephalic astrocyte-derived neurotrophic factor homolog (MANF/CDNF-like protein),Mesencephalic astrocyte-derived neurotrophic factor homolog (MANF/CDNF-like protein),GO:0005576; GO:0007275,extracellular region; multicellular organismal development,PF10208;,,,,,,,,,ARMET_DROSI,Drosophila simulans (Fruit fly),multicellular organism development [GO:0007275] comp142730_c0_seq1,3008,40.0266,0.50461183,220,1640,,0,Q9H6R0,Putative ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33),Putative ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33),GO:0005524; GO:0008026; GO:0005730; GO:0005654; GO:0045943; GO:0000182,ATP binding; ATP-dependent helicase activity; nucleolus; nucleoplasm; positive regulation of transcription from RNA polymerase I promoter; rDNA binding,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_LOC101170865.1.1,,,,,,,DHX33_HUMAN,Homo sapiens (Human),positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; RNA processing [GO:0006396] comp142731_c0_seq2,327,45.2599,0.5406644,5,14,,5.00E-14,Q2U968,COPII coat assembly protein sec16 (Protein transport protein sec16),COPII coat assembly protein sec16 (Protein transport protein sec16),GO:0048208; GO:0006914; GO:0005789; GO:0015031,COPII vesicle coating; autophagy; endoplasmic reticulum membrane; protein transport,PF12932;PF12931;PF12935;,,,,,,,,,SEC16_ASPOR,Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold),autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; protein transport [GO:0015031] comp142731_c0_seq5,1881,47.9001,0.67686363,134,82,,4.00E-94,O15027,Protein transport protein Sec16A (SEC16 homolog A),Protein transport protein Sec16A (SEC16 homolog A),GO:0048208; GO:0000139; GO:0005829; GO:0005789; GO:0007029; GO:0015031,COPII vesicle coating; Golgi membrane; cytosol; endoplasmic reticulum membrane; endoplasmic reticulum organization; protein transport,PF12932;PF12931;,1.00E-94,CHOYP_LOC588883.3.3,,,,,,,SC16A_HUMAN,Homo sapiens (Human),COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; protein transport [GO:0015031]; substantia nigra development [GO:0021762] comp142732_c1_seq1,2343,44.9424,0.51588983,17,41,,3.00E-27,Q5R413,mRNA-decapping enzyme 1B (EC 3.-.-.-),mRNA-decapping enzyme 1B (EC 3.-.-.-),GO:0005737; GO:0016787; GO:0000184; GO:0005634,"cytoplasm; hydrolase activity; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus",PF06058;PF16741;,2.00E-16,CHOYP_LOC100554670.1.1,,,,,,,DCP1B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp142732_c1_seq2,2640,43.8636,0.47284562,7,63,,2.00E-25,Q3SZL6,mRNA-decapping enzyme 1B (EC 3.-.-.-),mRNA-decapping enzyme 1B (EC 3.-.-.-),GO:0005737; GO:0016787; GO:0000184; GO:0005634,"cytoplasm; hydrolase activity; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus",PF06058;PF16741;,,,,,,,,,DCP1B_BOVIN,Bos taurus (Bovine),"deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp142733_c0_seq1,1336,34.3563,0.43188061,350,555,,2.00E-34,Q9Y547,Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25),Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25),GO:0007155; GO:0005929; GO:0030992; GO:0006950,cell adhesion; cilium; intraflagellar transport particle B; response to stress,PF00754;,2.00E-15,CHOYP_LOC764898.1.1,4.00E-40,ruditapes_c10902,,,,,HSB11_HUMAN,Homo sapiens (Human),heart development [GO:0007507]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; protein transport [GO:0015031]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] comp142733_c2_seq1,1128,38.4752,1.2484433,0,226,,6.00E-17,P33300,Mannosyl phosphorylinositol ceramide synthase SUR1 (EC 2.4.-.-),Mannosyl phosphorylinositol ceramide synthase SUR1 (EC 2.4.-.-),GO:0006688; GO:0016021; GO:0005622; GO:0006675; GO:0000030,glycosphingolipid biosynthetic process; integral to membrane; intracellular; mannosyl-inositol phosphorylceramide metabolic process; mannosyltransferase activity,PF04488;,,,,,,,,,SUR1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),glycosphingolipid biosynthetic process [GO:0006688]; mannosyl-inositol phosphorylceramide biosynthetic process [GO:0051999]; mannosyl-inositol phosphorylceramide metabolic process [GO:0006675]; sphingolipid biosynthetic process [GO:0030148] comp142734_c1_seq1,2115,36.7376,0.36508914,764,1702,,2.00E-40,Q6PBK1,Coiled-coil domain-containing protein 58,Coiled-coil domain-containing protein 58,,,PF09774;,,,,,,,,,CCD58_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142737_c0_seq2,1467,45.1943,0.53583512,155,133,,5.00E-106,Q921F2,TAR DNA-binding protein 43 (TDP-43),TAR DNA-binding protein 43 (TDP-43),GO:0070935; GO:0001205; GO:0008380; GO:0003690; GO:0003730; GO:0006397; GO:0043922; GO:0000166; GO:0005634,3'-UTR-mediated mRNA stabilization; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA splicing; double-stranded DNA binding; mRNA 3'-UTR binding; mRNA processing; negative regulation by host of viral transcription; nucleotide binding; nucleus,PF00076;,2.00E-71,CHOYP_LOC656201.1.1,,,,,,,TADBP_MOUSE,Mus musculus (Mouse),3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; regulation of cell cycle [GO:0051726]; response to endoplasmic reticulum stress [GO:0034976]; RNA splicing [GO:0008380] comp142739_c0_seq2,2966,42.5826,0.52339653,22,41,,0,P50416,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0006853; GO:0042755; GO:0006635; GO:0006006; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; carnitine shuttle; eating behavior; fatty acid beta-oxidation; glucose metabolic process; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; triglyceride metabolic process,PF00755;PF16484;,,,,,,,,,CPT1A_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641] comp142739_c0_seq3,2931,42.6476,0.52098141,30,3,,0,P50416,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0006853; GO:0042755; GO:0006635; GO:0006006; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; carnitine shuttle; eating behavior; fatty acid beta-oxidation; glucose metabolic process; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; triglyceride metabolic process,PF00755;PF16484;,0,CHOYP_LOC100647521.2.2,,,,,,,CPT1A_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641] comp142742_c0_seq1,2010,40,0.46125294,231,646,,8.00E-19,Q640Z9,Leucine-rich repeat-containing protein 14,Leucine-rich repeat-containing protein 14,,,PF13516;,2.00E-23,CHOYP_LRC14.1.1,,,,,,,LRC14_XENLA,Xenopus laevis (African clawed frog), comp142743_c0_seq1,5555,31.5572,0.47378407,206,676,,1.00E-125,Q05975,Ras-related protein Rab-2,Ras-related protein Rab-2,GO:0005525; GO:0000139; GO:0005789; GO:0033116; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00071;,4.00E-36,CHOYP_LOC762871.1.1,8.00E-132,ruditapes_c14666,,,,,RAB2_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp142747_c0_seq1,3285,42.6484,0.50436941,4944,623,,0,Q4R6T7,IQ and ubiquitin-like domain-containing protein,IQ and ubiquitin-like domain-containing protein,GO:0030030,cell projection organization,,0,CHOYP_LOC100375473.1.1,4.00E-88,ruditapes_c21039,0,AM860498.p.cg.6,4,female gonad,IQUB_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell projection organization [GO:0030030] comp142749_c0_seq3,1344,37.872,0.86193133,21,82,,1.00E-12,Q5BIS9,5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb),5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb),GO:0006633; GO:0005634; GO:0010628; GO:0004672,fatty acid biosynthetic process; nucleus; positive regulation of gene expression; protein kinase activity,PF16561;PF04739;,,,,,,,,,AAKB1_BOVIN,Bos taurus (Bovine),fatty acid biosynthetic process [GO:0006633]; positive regulation of gene expression [GO:0010628]; regulation of protein kinase activity [GO:0045859]; signal transduction [GO:0007165] comp142749_c0_seq4,2058,37.6579,0.75543436,75,1077,,3.00E-09,Q944A6,Sucrose nonfermenting 4-like protein (SNF4) (CBS domain-containing protein CBSCBS3) (SNF1-related protein kinase regulatory subunit betagamma) (AKIN subunit betagamma) (AKINbetagamma),Sucrose nonfermenting 4-like protein (SNF4) (CBS domain-containing protein CBSCBS3) (SNF1-related protein kinase regulatory subunit betagamma) (AKIN subunit betagamma) (AKINbetagamma),GO:0030554; GO:0005975; GO:0042149; GO:0005737; GO:0005634; GO:0046777; GO:0030295; GO:0004674,adenyl nucleotide binding; carbohydrate metabolic process; cellular response to glucose starvation; cytoplasm; nucleus; protein autophosphorylation; protein kinase activator activity; protein serine/threonine kinase activity,PF16561;PF00571;,,,,,,,,,SNF4_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975]; cellular response to glucose starvation [GO:0042149]; protein autophosphorylation [GO:0046777]; regulation of protein kinase activity [GO:0045859] comp142752_c0_seq1,986,44.4219,0.6231067,420,5,,1.00E-82,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DNAH12.2.3,2.00E-35,ruditapes_c22262,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp142752_c1_seq1,2379,46.6583,0.56714031,287,0,male,0,Q63170,"Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)","Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0005509; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; calcium ion binding; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,7.00E-48,CHOYP_DNAH7.1.2,,,,,,,DYH7_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341] comp142752_c1_seq2,1651,46.6384,0.51560568,3,0,,,,,,,,,7.00E-40,CHOYP_LOC587136.2.3,,,,,,,,, comp142753_c0_seq10,2576,40.4503,0.45417361,0,0,,1.00E-75,Q63312,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment),GO:0005543,phospholipid binding,PF00169;,1.00E-134,CHOYP_PHLB1.1.1,,,,,,,PHLB1_RAT,Rattus norvegicus (Rat), comp142753_c0_seq11,3692,40.3846,0.44066188,0,0,,2.00E-74,Q63312,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment),GO:0005543,phospholipid binding,PF00169;,,,,,,,,,PHLB1_RAT,Rattus norvegicus (Rat), comp142753_c0_seq12,3809,40.0893,0.44040471,0,0,,,,,,,,,2.00E-134,CHOYP_LOC100368104.1.1,,,,,,,,, comp142753_c0_seq15,2645,40.5671,0.46748793,0,0,,1.00E-75,Q6PDH0,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),GO:0005543,phospholipid binding,PF00169;,5.00E-145,CHOYP_PHLB1.1.1,,,,,,,PHLB1_MOUSE,Mus musculus (Mouse),positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507] comp142753_c0_seq3,2528,41.0206,0.46796201,0,0,,1.00E-75,Q6PDH0,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),GO:0005543,phospholipid binding,PF00169;,5.00E-145,CHOYP_PHLB1.1.1,,,,,,,PHLB1_MOUSE,Mus musculus (Mouse),positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507] comp142753_c0_seq4,2459,40.9109,0.45438491,0,0,,7.00E-76,Q63312,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment),GO:0005543,phospholipid binding,PF00169;,1.00E-134,CHOYP_LOC100368104.1.1,,,,,,,PHLB1_RAT,Rattus norvegicus (Rat), comp142753_c0_seq5,3692,40.4659,0.45182443,0,0,,,,,,,,,2.00E-134,CHOYP_LOC100368104.1.1,,,,,,,,, comp142753_c0_seq7,3761,40.468,0.45033026,0,0,,,,,,,,,8.00E-145,CHOYP_PHLB1.1.1,,,,,,,,, comp142753_c0_seq8,3761,40.5477,0.46119661,0,0,,,,,,,,,8.00E-145,CHOYP_PHLB1.1.1,,,,,,,,, comp142754_c0_seq1,3329,38.0895,0.36477164,0,0,,2.00E-64,Q9D8M7,PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a),PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a),GO:0007399; GO:0071564; GO:0006355; GO:0006351; GO:0008270,"nervous system development; npBAF complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;,,,,,,,,,PHF10_MOUSE,Mus musculus (Mouse),"nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142754_c0_seq2,1461,40.2464,0.35009595,0,1,,3.00E-23,A9LMC0,Zinc finger protein DPF3,Zinc finger protein DPF3,GO:0016514; GO:0055008; GO:0016568; GO:0042393; GO:0007399; GO:0006355; GO:0006351; GO:0008270,"SWI/SNF complex; cardiac muscle tissue morphogenesis; chromatin modification; histone binding; nervous system development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,2.00E-45,CHOYP_PHF10.1.1,,,,,,,DPF3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cardiac muscle tissue morphogenesis [GO:0055008]; chromatin modification [GO:0016568]; muscle organ morphogenesis [GO:0048644]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142754_c0_seq5,1554,39.4466,0.34227744,17,109,,4.00E-23,A9LMC0,Zinc finger protein DPF3,Zinc finger protein DPF3,GO:0016514; GO:0055008; GO:0016568; GO:0042393; GO:0007399; GO:0006355; GO:0006351; GO:0008270,"SWI/SNF complex; cardiac muscle tissue morphogenesis; chromatin modification; histone binding; nervous system development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,2.00E-45,CHOYP_PHF10.1.1,,,,,,,DPF3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cardiac muscle tissue morphogenesis [GO:0055008]; chromatin modification [GO:0016568]; muscle organ morphogenesis [GO:0048644]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142754_c0_seq7,2852,38.4993,0.35968725,0,0,,1.00E-64,Q9D8M7,PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a),PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a),GO:0007399; GO:0071564; GO:0006355; GO:0006351; GO:0008270,"nervous system development; npBAF complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;,,,,,,,,,PHF10_MOUSE,Mus musculus (Mouse),"nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142754_c0_seq8,2334,40.0171,0.36427808,0,0,,3.00E-33,Q9VWF2,Supporter of activation of yellow protein (Protein enhancer of yellow 3),Supporter of activation of yellow protein (Protein enhancer of yellow 3),GO:0070604; GO:0003682; GO:0005737; GO:0000791; GO:0016458; GO:0000792; GO:0007480; GO:0031936; GO:0045892; GO:0005701; GO:0046427; GO:0006351; GO:0008270,"PBAF complex; chromatin binding; cytoplasm; euchromatin; gene silencing; heterochromatin; imaginal disc-derived leg morphogenesis; negative regulation of chromatin silencing; negative regulation of transcription, DNA-dependent; polytene chromosome chromocenter; positive regulation of JAK-STAT cascade; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,SAYP_DROME,Drosophila melanogaster (Fruit fly),"gene silencing [GO:0016458]; imaginal disc-derived leg morphogenesis [GO:0007480]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp142754_c0_seq9,2228,40.6194,0.37009819,0,0,,2.00E-65,Q9D8M7,PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a),PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a),GO:0007399; GO:0071564; GO:0006355; GO:0006351; GO:0008270,"nervous system development; npBAF complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;,4.00E-45,CHOYP_PHF10.1.1,,,,,,,PHF10_MOUSE,Mus musculus (Mouse),"nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142755_c0_seq10,1174,39.7785,0.37891749,0,0,,3.00E-20,Q54Y27,FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005528; GO:0016020; GO:0003755; GO:0006457,FK506 binding; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;PF00515;,,,,,,,,,FKBP6_DICDI,Dictyostelium discoideum (Slime mold),chaperone-mediated protein folding [GO:0061077] comp142755_c0_seq12,1785,40.6723,0.32020152,0,0,,5.00E-07,Q9M2S7,Peptidyl-prolyl cis-trans isomerase FKBP20-1 (PPIase FKBP20-1) (EC 5.2.1.8) (FK506-binding protein 20-1) (AtFKBP20-1) (Immunophilin FKBP20-1) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP20-1 (PPIase FKBP20-1) (EC 5.2.1.8) (FK506-binding protein 20-1) (AtFKBP20-1) (Immunophilin FKBP20-1) (Rotamase),GO:0005528; GO:0016020; GO:0003755; GO:0006457,FK506 binding; membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,,,,,,,,,FK201_ARATH,Arabidopsis thaliana (Mouse-ear cress),chaperone-mediated protein folding [GO:0061077] comp142755_c0_seq18,1657,41.2794,0.24603066,0,0,,3.00E-44,Q3B7U9,Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (FK506-binding protein 8) (FKBP-8) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (FK506-binding protein 8) (FKBP-8) (Rotamase),GO:0005528; GO:0006915; GO:0030176; GO:0005740; GO:0031966; GO:0003755; GO:0006457,FK506 binding; apoptotic process; integral to endoplasmic reticulum membrane; mitochondrial envelope; mitochondrial membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,,,,,,,,,FKBP8_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; chaperone-mediated protein folding [GO:0061077]; dorsal/ventral neural tube patterning [GO:0021904]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224] comp142755_c0_seq2,2696,43.3234,0.26273206,8,0,,8.00E-34,Q14318,Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase),GO:0005528; GO:0006915; GO:0043010; GO:0001708; GO:0021904; GO:0030176; GO:0035556; GO:0046872; GO:0005740; GO:0031966; GO:0019048; GO:0035264; GO:0003755; GO:0030513; GO:0006457; GO:0010468; GO:0007224,FK506 binding; apoptotic process; camera-type eye development; cell fate specification; dorsal/ventral neural tube patterning; integral to endoplasmic reticulum membrane; intracellular signal transduction; metal ion binding; mitochondrial envelope; mitochondrial membrane; modulation by virus of host morphology or physiology; multicellular organism growth; peptidyl-prolyl cis-trans isomerase activity; positive regulation of BMP signaling pathway; protein folding; regulation of gene expression; smoothened signaling pathway,PF00254;PF07719;,,,,,,,,,FKBP8_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; chaperone-mediated protein folding [GO:0061077]; dorsal/ventral neural tube patterning [GO:0021904]; intracellular signal transduction [GO:0035556]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224]; viral process [GO:0016032] comp142755_c0_seq5,2552,44.4357,0.23974536,16,0,,4.00E-17,P0C1J7,FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00254;PF13181;,,,,,,,,,FKBP5_RHIO9,Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar),protein folding [GO:0006457] comp142755_c0_seq7,1640,42.0732,0.28320213,0,0,,2.00E-44,Q3B7U9,Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (FK506-binding protein 8) (FKBP-8) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (FK506-binding protein 8) (FKBP-8) (Rotamase),GO:0005528; GO:0006915; GO:0030176; GO:0005740; GO:0031966; GO:0003755; GO:0006457,FK506 binding; apoptotic process; integral to endoplasmic reticulum membrane; mitochondrial envelope; mitochondrial membrane; peptidyl-prolyl cis-trans isomerase activity; protein folding,PF00254;,,,,,,,,,FKBP8_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; chaperone-mediated protein folding [GO:0061077]; dorsal/ventral neural tube patterning [GO:0021904]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224] comp142755_c0_seq9,604,39.7351,0.39828944,5,0,,2.00E-09,Q5RAP0,Protein unc-45 homolog A (Unc-45A) (Smooth muscle cell-associated protein 1) (SMAP-1),Protein unc-45 homolog A (Unc-45A) (Smooth muscle cell-associated protein 1) (SMAP-1),GO:0030154; GO:0007517; GO:0005634; GO:0048471,cell differentiation; muscle organ development; nucleus; perinuclear region of cytoplasm,PF13181;PF11701;,,,,,,,,,UN45A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell differentiation [GO:0030154]; muscle organ development [GO:0007517] comp142756_c4_seq2,1546,44.6313,0.50691076,0,6,,2.00E-29,Q7LHG5,Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,5.00E-73,CHOYP_LOC100330808.2.2,,,,,,,YI31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp142757_c0_seq4,1528,32.7225,0.45021367,9,42,,2.00E-09,Q24JY3,Kinetochore protein Spc24,Kinetochore protein Spc24,GO:0031262; GO:0051301; GO:0000777; GO:0007067; GO:0005634,Ndc80 complex; cell division; condensed chromosome kinetochore; mitosis; nucleus,PF08286;,,,3.00E-35,ruditapes_c8141,,,,,SPC24_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp142759_c0_seq1,1738,35.6732,0.806343,26,302,,,,,,,,,,,6.00E-121,ruditapes2_c807,,,,,,, comp142759_c0_seq2,564,35.8156,0.84508813,0,14,,9.00E-87,Q9DB50,AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 subunit sigma-1B) (Adaptor protein complex AP-1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin),AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin),GO:0005794; GO:0005905; GO:0030659; GO:0006897; GO:0006886; GO:0030117; GO:0008565,Golgi apparatus; coated pit; cytoplasmic vesicle membrane; endocytosis; intracellular protein transport; membrane coat; protein transporter activity,PF01217;,,,,,,,,,AP1S2_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; intracellular protein transport [GO:0006886]; neuromuscular process controlling balance [GO:0050885]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192]; visual learning [GO:0008542] comp142759_c0_seq4,2327,33.7774,0.84302591,6,166,,7.00E-41,Q54WW3,AP-1 complex subunit sigma-1 (Adapter-related protein complex 1 subunit sigma-1A) (Adaptor protein complex AP-1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin),AP-1 complex subunit sigma-1 (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin),GO:0005794; GO:0030665; GO:0006897; GO:0008565,Golgi apparatus; clathrin-coated vesicle membrane; endocytosis; protein transporter activity,PF01217;,6.00E-106,CHOYP_LOC659702.1.1,,,,,,,AP1S1_DICDI,Dictyostelium discoideum (Slime mold), comp142760_c0_seq1,2789,40.1219,0.52022125,0,0,,3.00E-170,Q5R469,Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor),Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor),GO:0003677; GO:0003723; GO:0008380; GO:0006915; GO:0006397; GO:0000166; GO:0005634; GO:0006355; GO:0030529; GO:0006351,"DNA binding; RNA binding; RNA splicing; apoptotic process; mRNA processing; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF00076;,2.00E-144,CHOYP_LOC100367069.1.1,,,,,,,PUF60_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142760_c0_seq2,2774,40.1226,0.52290455,0,8,,2.00E-170,Q5R469,Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor),Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor),GO:0003677; GO:0003723; GO:0008380; GO:0006915; GO:0006397; GO:0000166; GO:0005634; GO:0006355; GO:0030529; GO:0006351,"DNA binding; RNA binding; RNA splicing; apoptotic process; mRNA processing; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF00076;,2.00E-144,CHOYP_LOC100367069.1.1,,,,,,,PUF60_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142760_c0_seq3,2508,38.7161,0.51337672,5,7,,1.00E-21,P0CB38,Polyadenylate-binding protein 4-like (PABP-4-like) (Poly(A)-binding protein 4-like),Polyadenylate-binding protein 4-like (PABP-4-like) (Poly(A)-binding protein 4-like),GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,,,,,,,,,PAB4L_HUMAN,Homo sapiens (Human), comp142760_c0_seq4,2901,39.1244,0.49955249,0,31,,8.00E-170,Q9WV25,Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (RNA-binding protein Siah-BP) (Siah-binding protein 1),Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (RNA-binding protein Siah-BP) (Siah-binding protein 1),GO:0003677; GO:0003723; GO:0008380; GO:0006915; GO:0019907; GO:0006397; GO:0000166; GO:0006355; GO:0030529; GO:0006351,"DNA binding; RNA binding; RNA splicing; apoptotic process; cyclin-dependent protein kinase activating kinase holoenzyme complex; mRNA processing; nucleotide binding; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF00076;,,,,,,,,,PUF60_RAT,Rattus norvegicus (Rat),"apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142760_c0_seq5,2523,38.6841,0.50071129,0,0,,1.00E-20,A1CRM1,"Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)","Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)",GO:0003723; GO:0005737; GO:0006397; GO:0051028; GO:0000166; GO:0005634; GO:0006417,RNA binding; cytoplasm; mRNA processing; mRNA transport; nucleotide binding; nucleus; regulation of translation,PF00658;PF00076;,,,,,,,,,PABP_ASPCL,Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417] comp142760_c0_seq8,2917,39.1841,0.50424925,6,22,,3.00E-170,Q5R469,Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor),Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor),GO:0003677; GO:0003723; GO:0008380; GO:0006915; GO:0006397; GO:0000166; GO:0005634; GO:0006355; GO:0030529; GO:0006351,"DNA binding; RNA binding; RNA splicing; apoptotic process; mRNA processing; nucleotide binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF00076;,2.00E-144,CHOYP_LOC100367069.1.1,,,,,,,PUF60_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp142762_c0_seq1,3654,42.3372,0.36659247,0,0,,1.00E-13,Q8C0P7,Zinc finger protein 451,E3 SUMO-protein ligase ZNF451 (Zinc finger protein 451) (EC 6.3.2.-),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN451_MOUSE,Mus musculus (Mouse),"negative regulation of histone H3-K9 acetylation [GO:2000616]; negative regulation of transcription initiation from RNA polymerase II promoter [GO:0060633]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]" comp142762_c0_seq3,869,36.0184,0.71305725,979,939,,9.00E-36,Q8C0P7,Zinc finger protein 451,E3 SUMO-protein ligase ZNF451 (Zinc finger protein 451) (EC 6.3.2.-),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN451_MOUSE,Mus musculus (Mouse),"negative regulation of histone H3-K9 acetylation [GO:2000616]; negative regulation of transcription initiation from RNA polymerase II promoter [GO:0060633]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]" comp142763_c1_seq1,1044,38.7931,0.5774066,28,12,,,,,,,,,2.00E-31,CHOYP_BRAFLDRAFT_117177.1.1,,,,,,,,, comp142763_c1_seq3,628,44.2675,0.5651407,121,71,,7.00E-56,Q6PGE7,Sodium-dependent proline transporter (Solute carrier family 6 member 7),Sodium-dependent proline transporter (Solute carrier family 6 member 7),GO:0006865; GO:0016021; GO:0005328,amino acid transport; integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,4.00E-50,CHOYP_BRAFLDRAFT_117178.1.1,,,,,,,SC6A7_MOUSE,Mus musculus (Mouse),proline transmembrane transport [GO:0035524] comp142763_c1_seq6,1345,35.2416,0.36070983,0,0,,,,,,,,,7.00E-58,CHOYP_SC6A1.1.1,,,,,,,,, comp142763_c1_seq7,1405,40.7829,0.52543751,0,0,,3.00E-38,Q9XS59,Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3),Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3),GO:0005887; GO:0015820; GO:0005328; GO:0005298,integral to plasma membrane; leucine transport; neurotransmitter:sodium symporter activity; proline:sodium symporter activity,PF00209;,3.00E-31,CHOYP_BRAFLDRAFT_117177.1.1,,,,,,,S6A15_BOVIN,Bos taurus (Bovine),leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824] comp142763_c1_seq8,1598,36.9212,0.40452633,0,0,,,,,,,,,3.00E-82,CHOYP_SC6A1.1.1,,,,,,,,, comp142763_c1_seq9,2753,37.777,0.433735,166,211,,8.00E-129,A7Y2W8,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),GO:0005887; GO:0005328; GO:0005283,integral to plasma membrane; neurotransmitter:sodium symporter activity; sodium:amino acid symporter activity,PF00209;,5.00E-127,CHOYP_LOC100375514.4.6,,,,,,,SC6A9_XENLA,Xenopus laevis (African clawed frog), comp142766_c0_seq1,2640,45.303,0.65802464,49,1370,,7.00E-137,Q5R733,Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (CPEB-1),Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (CPEB-1),GO:0003723; GO:0030054; GO:0000932; GO:0030425; GO:0006397; GO:0046872; GO:0000166; GO:0014069; GO:0045211; GO:0006417,RNA binding; cell junction; cytoplasmic mRNA processing body; dendrite; mRNA processing; metal ion binding; nucleotide binding; postsynaptic density; postsynaptic membrane; regulation of translation,PF16368;PF16366;PF16367;,2.00E-175,CHOYP_CPEB.2.2,,,,,,,CPEB1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; mRNA processing [GO:0006397]; negative regulation of cytoplasmic translation [GO:2000766] comp142769_c0_seq1,3186,39.4225,0.48693292,152,120,,0,O43592,Exportin-T (Exportin(tRNA)) (tRNA exportin),Exportin-T (Exportin(tRNA)) (tRNA exportin),GO:0005737; GO:0006886; GO:0005654; GO:0000049; GO:0006409,cytoplasm; intracellular protein transport; nucleoplasm; tRNA binding; tRNA export from nucleus,PF03810;PF08389;,0,CHOYP_XPOT.1.1,,,,,,,XPOT_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; tRNA export from nucleus [GO:0006409]; tRNA re-export from nucleus [GO:0071528] comp142769_c1_seq1,911,44.7859,0.41929056,32,11,,4.00E-34,Q6C715,Exportin-T (Exportin(tRNA)) (Karyopherin-beta) (tRNA exportin),Exportin-T (Exportin(tRNA)) (Karyopherin-beta) (tRNA exportin),GO:0005737; GO:0005634; GO:0000049; GO:0008033; GO:0006810,cytoplasm; nucleus; tRNA binding; tRNA processing; transport,PF08389;,,,,,,,,,XPOT_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),tRNA processing [GO:0008033]; tRNA re-export from nucleus [GO:0071528] comp142770_c0_seq1,3103,37.4154,1.05017373,5180,0,,3.00E-15,Q21734,Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1),Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1),GO:0005524; GO:0007243; GO:0000287; GO:0004674,ATP binding; intracellular protein kinase cascade; magnesium ion binding; protein serine/threonine kinase activity,PF00069;PF00433;,,,,,,,,,KS6A1_CAEEL,Caenorhabditis elegans,intracellular signal transduction [GO:0035556] comp142772_c0_seq1,3486,45.3815,0.63578824,670,4706,,0,P28271,Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1),Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1),GO:0051539; GO:0005794; GO:0003994; GO:0006879; GO:0006101; GO:0005829; GO:0005783; GO:0050892; GO:0030350; GO:0046872; GO:0005739; GO:0009791; GO:0006417; GO:0010040; GO:0006099,"4 iron, 4 sulfur cluster binding; Golgi apparatus; aconitate hydratase activity; cellular iron ion homeostasis; citrate metabolic process; cytosol; endoplasmic reticulum; intestinal absorption; iron-responsive element binding; metal ion binding; mitochondrion; post-embryonic development; regulation of translation; response to iron(II) ion; tricarboxylic acid cycle",PF00330;PF00694;,0,CHOYP_ACO1.1.1,,,,,,,ACOC_MOUSE,Mus musculus (Mouse),cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099] comp142773_c0_seq2,2843,36.5459,0.47643517,79,188,,1.00E-52,Q9Y3D0,Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B),Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B),GO:0097361; GO:0071817; GO:0007059; GO:0005634; GO:0044281,CIA complex; MMXD complex; chromosome segregation; nucleus; small molecule metabolic process,PF01883;,7.00E-68,CHOYP_LOC496139.1.1,,,,,,,MIP18_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226] comp142773_c0_seq3,2832,36.3347,0.46265539,20,17,,1.00E-52,Q9Y3D0,Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B),Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B),GO:0097361; GO:0071817; GO:0007059; GO:0005634; GO:0044281,CIA complex; MMXD complex; chromosome segregation; nucleus; small molecule metabolic process,PF01883;,7.00E-68,CHOYP_LOC496139.1.1,,,,,,,MIP18_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226] comp142774_c0_seq3,1498,40.1202,0.35247698,5,68,,5.00E-95,Q5PR55,Uncharacterized protein C12orf29 homolog,Uncharacterized protein C12orf29 homolog,,,,,,,,,,,,CL029_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142778_c0_seq1,2833,34.557,0.31056491,167,934,,6.00E-46,Q9NRY5,Protein FAM114A2,Protein FAM114A2,GO:0017076,purine nucleotide binding,PF05334;,,,,,,,,,F1142_HUMAN,Homo sapiens (Human), comp142778_c0_seq2,294,44.5578,0.28921903,8,44,,4.00E-13,Q9NRY5,Protein FAM114A2,Protein FAM114A2,GO:0017076,purine nucleotide binding,PF05334;,2.00E-13,CHOYP_LOC100370330.1.1,,,,,,,F1142_HUMAN,Homo sapiens (Human), comp142779_c0_seq1,3410,44.6921,0.59230786,0,0,,6.00E-93,Q98930,Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment),Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment),GO:0008203; GO:0006897; GO:0016021; GO:0006869; GO:0034362,cholesterol metabolic process; endocytosis; integral to membrane; lipid transport; low-density lipoprotein particle,PF00041;PF00057;PF00058;PF15902;PF15901;,5.00E-20,CHOYP_LRP1.5.5,,,,,,,SORL_CHICK,Gallus gallus (Chicken),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869] comp142779_c0_seq10,714,47.0588,0.69285568,0,0,,2.00E-15,Q86YD5,Low-density lipoprotein receptor class A domain-containing protein 3,Low-density lipoprotein receptor class A domain-containing protein 3,GO:0001540; GO:0016021; GO:0005886; GO:0006898; GO:0070613,beta-amyloid binding; integral to membrane; plasma membrane; receptor-mediated endocytosis; regulation of protein processing,PF00057;,,,,,,,,,LRAD3_HUMAN,Homo sapiens (Human),receptor-mediated endocytosis [GO:0006898]; regulation of protein processing [GO:0070613] comp142779_c0_seq2,5640,45.0709,0.61130974,2,4,,0,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,3.00E-19,CHOYP_LRP1.3.5,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp142779_c0_seq3,4946,45.5924,0.60912807,9,0,,0,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp142779_c0_seq4,3612,45.072,0.64986477,0,0,,0,Q9JI18,Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),GO:0005509; GO:0016021; GO:0050750; GO:0005041; GO:0016020,calcium ion binding; integral to membrane; low-density lipoprotein particle receptor binding; low-density lipoprotein receptor activity; membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1B_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701] comp142779_c0_seq5,2918,45.8191,0.65065888,0,0,,3.00E-130,P98155,Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),GO:0034185; GO:0005509; GO:0008203; GO:0005905; GO:0034436; GO:0034437; GO:0016021; GO:0006869; GO:0005041; GO:0007613; GO:0000122; GO:0005886; GO:1900006; GO:0045860; GO:0038025; GO:0021517; GO:0034361; GO:0034189; GO:0034447; GO:0030229,apolipoprotein binding; calcium ion binding; cholesterol metabolic process; coated pit; glycoprotein transport; glycoprotein transporter activity; integral to membrane; lipid transport; low-density lipoprotein receptor activity; memory; negative regulation of transcription from RNA polymerase II promoter; plasma membrane; positive regulation of dendrite development; positive regulation of protein kinase activity; reelin receptor activity; ventral spinal cord development; very-low-density lipoprotein particle; very-low-density lipoprotein particle binding; very-low-density lipoprotein particle clearance; very-low-density lipoprotein particle receptor activity,PF07645;PF00057;PF00058;,4.00E-20,CHOYP_LRP1.5.5,,,,,,,VLDLR_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex development [GO:0021987]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; heart development [GO:0007507]; lipid transport [GO:0006869]; memory [GO:0007613]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; signal transduction [GO:0007165]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] comp142779_c0_seq6,531,42.1846,0.69656548,0,0,,8.00E-07,B0WH58,Protein cueball,Protein cueball,GO:0030154; GO:0016021; GO:0048477; GO:0005886; GO:0007283,cell differentiation; integral to membrane; oogenesis; plasma membrane; spermatogenesis,PF12661;,,,,,,,,,CUE_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),oogenesis [GO:0048477]; spermatogenesis [GO:0007283] comp142779_c0_seq7,2003,45.4319,0.57007504,0,0,,1.00E-111,P98157,Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),GO:0005509; GO:0005905; GO:0006897; GO:0016021,calcium ion binding; coated pit; endocytosis; integral to membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp142779_c0_seq8,1382,43.9942,0.65948535,0,0,,3.00E-128,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,2.00E-20,CHOYP_LRP1.5.5,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp142780_c0_seq2,3774,43.2697,0.41520896,0,0,,6.00E-39,Q12912,Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein],Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein],GO:0005789; GO:0030176; GO:0005887; GO:0006906; GO:0006903,endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to plasma membrane; vesicle fusion; vesicle targeting,PF05781;,6.00E-32,CHOYP_LOC100379008.2.4,,,,,,,LRMP_HUMAN,Homo sapiens (Human),immune system process [GO:0002376]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] comp142780_c0_seq3,3894,43.246,0.4083573,0,0,,,,,,,,,8.00E-31,CHOYP_LOC100379008.1.4,,,,,,,,, comp142780_c0_seq4,3840,43.151,0.42164313,2,17,,8.00E-39,Q12912,Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein],Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein],GO:0005789; GO:0030176; GO:0005887; GO:0006906; GO:0006903,endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to plasma membrane; vesicle fusion; vesicle targeting,PF05781;,7.00E-32,CHOYP_LOC100379008.2.4,,,,,,,LRMP_HUMAN,Homo sapiens (Human),immune system process [GO:0002376]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] comp142780_c0_seq6,3822,43.2496,0.42178097,0,0,,7.00E-39,Q12912,Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein],Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein],GO:0005789; GO:0030176; GO:0005887; GO:0006906; GO:0006903,endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to plasma membrane; vesicle fusion; vesicle targeting,PF05781;,8.00E-31,CHOYP_LOC100379008.1.4,,,,,,,LRMP_HUMAN,Homo sapiens (Human),immune system process [GO:0002376]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] comp142780_c0_seq9,3792,43.2753,0.42436283,0,0,,3.00E-34,Q9WUX5,"Protein MRVI1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1) (Murine retrovirus integration site 1 protein)","Protein MRVI1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1) (Murine retrovirus integration site 1 protein)",GO:0016021; GO:0048471; GO:0016529,integral to membrane; perinuclear region of cytoplasm; sarcoplasmic reticulum,PF05781;,6.00E-32,CHOYP_LOC100379008.2.4,,,,,,,MRVI1_MOUSE,Mus musculus (Mouse),cGMP-mediated signaling [GO:0019934]; negative regulation of smooth muscle contraction [GO:0045986]; relaxation of vascular smooth muscle [GO:0060087] comp142781_c0_seq1,2994,39.9132,0.51275041,213,1346,,1.00E-121,O54862,Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease),Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease),GO:0008203; GO:0005737; GO:0016021; GO:0046872; GO:0004222; GO:0006508,cholesterol metabolic process; cytoplasm; integral to membrane; metal ion binding; metalloendopeptidase activity; proteolysis,PF02163;,4.00E-135,CHOYP_MBTPS2.1.1,,,,,,,MBTP2_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),cholesterol metabolic process [GO:0008203]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; response to endoplasmic reticulum stress [GO:0034976] comp142782_c0_seq14,1598,35.169,0.6492003,0,0,,5.00E-25,Q2KJG4,Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),GO:0005783; GO:0005789; GO:0008047; GO:0006750; GO:0004602; GO:0004364; GO:0016021; GO:0019370; GO:0004464; GO:0005635; GO:0005886; GO:0043085,endoplasmic reticulum; endoplasmic reticulum membrane; enzyme activator activity; glutathione biosynthetic process; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; leukotriene biosynthetic process; leukotriene-C4 synthase activity; nuclear envelope; plasma membrane; positive regulation of catalytic activity,PF01124;,,,,,,,,,MGST2_BOVIN,Bos taurus (Bovine),glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370] comp142782_c0_seq16,1531,34.8792,0.75683185,0,0,,4.00E-25,Q2KJG4,Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),GO:0005783; GO:0005789; GO:0008047; GO:0006750; GO:0004602; GO:0004364; GO:0016021; GO:0019370; GO:0004464; GO:0005635; GO:0005886; GO:0043085,endoplasmic reticulum; endoplasmic reticulum membrane; enzyme activator activity; glutathione biosynthetic process; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; leukotriene biosynthetic process; leukotriene-C4 synthase activity; nuclear envelope; plasma membrane; positive regulation of catalytic activity,PF01124;,,,,,,,,,MGST2_BOVIN,Bos taurus (Bovine),glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370] comp142782_c0_seq18,1540,35.5195,0.63976189,0,0,,6.00E-14,Q925U2,Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase),Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase),GO:0071222; GO:0071299; GO:0005783; GO:0005789; GO:0008047; GO:0043295; GO:0004602; GO:0004364; GO:0016021; GO:0019370; GO:0004464; GO:0005635; GO:0005640; GO:0043085; GO:0048678; GO:0042493; GO:0010035,cellular response to lipopolysaccharide; cellular response to vitamin A; endoplasmic reticulum; endoplasmic reticulum membrane; enzyme activator activity; glutathione binding; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; leukotriene biosynthetic process; leukotriene-C4 synthase activity; nuclear envelope; nuclear outer membrane; positive regulation of catalytic activity; response to axon injury; response to drug; response to inorganic substance,PF01124;,,,,,,,,,LTC4S_RAT,Rattus norvegicus (Rat),cellular response to lipopolysaccharide [GO:0071222]; cellular response to vitamin A [GO:0071299]; leukotriene biosynthetic process [GO:0019370]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lipopolysaccharide [GO:0032496] comp142782_c0_seq5,1453,34.3427,0.6327856,0,0,,1.00E-13,Q2KJG4,Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18),GO:0005783; GO:0005789; GO:0008047; GO:0006750; GO:0004602; GO:0004364; GO:0016021; GO:0019370; GO:0004464; GO:0005635; GO:0005886; GO:0043085,endoplasmic reticulum; endoplasmic reticulum membrane; enzyme activator activity; glutathione biosynthetic process; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; leukotriene biosynthetic process; leukotriene-C4 synthase activity; nuclear envelope; plasma membrane; positive regulation of catalytic activity,PF01124;,,,,,,,,,MGST2_BOVIN,Bos taurus (Bovine),glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370] comp142782_c0_seq6,1585,35.3312,0.64834784,0,0,,7.00E-14,Q925U2,Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase),Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase),GO:0071222; GO:0071299; GO:0005783; GO:0005789; GO:0008047; GO:0043295; GO:0004602; GO:0004364; GO:0016021; GO:0019370; GO:0004464; GO:0005635; GO:0005640; GO:0043085; GO:0048678; GO:0042493; GO:0010035,cellular response to lipopolysaccharide; cellular response to vitamin A; endoplasmic reticulum; endoplasmic reticulum membrane; enzyme activator activity; glutathione binding; glutathione peroxidase activity; glutathione transferase activity; integral to membrane; leukotriene biosynthetic process; leukotriene-C4 synthase activity; nuclear envelope; nuclear outer membrane; positive regulation of catalytic activity; response to axon injury; response to drug; response to inorganic substance,PF01124;,,,,,,,,,LTC4S_RAT,Rattus norvegicus (Rat),cellular response to lipopolysaccharide [GO:0071222]; cellular response to vitamin A [GO:0071299]; leukotriene biosynthetic process [GO:0019370]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lipopolysaccharide [GO:0032496] comp142786_c0_seq1,4257,43.9042,0.53906926,0,0,,0,Q8CGF7,Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),GO:0001106; GO:0005634; GO:0070064; GO:0003700; GO:0006351,"RNA polymerase II transcription corepressor activity; nucleus; proline-rich region binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01846;PF00397;,3.00E-94,CHOYP_TCRG1.1.1,,,,,,,TCRG1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp142786_c0_seq2,4293,44.0717,0.5303074,46,109,,,,,,,,,1.00E-92,CHOYP_BRAFLDRAFT_117283.2.2,,,,,,,,, comp142786_c0_seq3,4120,43.665,0.52254829,0,0,,7.00E-179,Q8CGF7,Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144),GO:0001106; GO:0005634; GO:0070064; GO:0003700; GO:0006351,"RNA polymerase II transcription corepressor activity; nucleus; proline-rich region binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01846;PF00397;,1.00E-92,CHOYP_TCERG1.1.1,9.00E-92,ruditapes_c21300,,,,,TCRG1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp142786_c0_seq4,1078,40.4453,0.77667051,24,147,,,,,,,,,,,8.00E-16,ruditapes2_c2388,,,,,,, comp142786_c0_seq5,4156,43.7921,0.51474005,0,0,,1.00E-08,B6EUA9,Pre-mRNA-processing protein 40A (Mediator of RNA polymerase II transcription subunit 35a),Pre-mRNA-processing protein 40A (Mediator of RNA polymerase II transcription subunit 35a),GO:0008380; GO:0005829; GO:0016592; GO:0006355; GO:0006351,"RNA splicing; cytosol; mediator complex; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01846;PF00397;,3.00E-163,CHOYP_TCRG1.1.1,,,,,,,PR40A_ARATH,Arabidopsis thaliana (Mouse-ear cress),"mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142787_c0_seq1,2694,37.9362,0.43819109,0,0,,3.00E-116,Q9WVC0,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0016020; GO:0030496; GO:0007067; GO:0016476; GO:0031105; GO:0005819,GTP binding; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; membrane; midbody; mitosis; regulation of embryonic cell shape; septin complex; spindle,PF00735;,,,,,,,,,SEPT7_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq10,2660,38.0451,0.46217618,0,0,,6.00E-161,Q91Y81,Septin-2 (Vascular endothelial cell specific protein 11),Septin-2 (Vascular endothelial cell specific protein 11),GO:0005525; GO:0003924; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0000145; GO:0030496; GO:0007067; GO:0031175; GO:0048471; GO:0031105; GO:0007224; GO:0005819,GTP binding; GTPase activity; cell division; cilium assembly; cilium membrane; cleavage furrow; exocyst; midbody; mitosis; neuron projection development; perinuclear region of cytoplasm; septin complex; smoothened signaling pathway; spindle,PF00735;,0,CHOYP_LOC100372339.1.2,,,,,,,SEPT2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq11,2668,38.0435,0.42964897,0,0,,4.00E-116,Q9WVC0,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0016020; GO:0030496; GO:0007067; GO:0016476; GO:0031105; GO:0005819,GTP binding; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; membrane; midbody; mitosis; regulation of embryonic cell shape; septin complex; spindle,PF00735;,6.00E-18,CHOYP_LOC373275.4.7,,,,,,,SEPT7_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq12,2680,38.097,0.43686863,0,0,,2.00E-157,P42207,Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),GO:0005525; GO:0003924; GO:0007049; GO:0051301; GO:0007349; GO:0045172; GO:0005875; GO:0043065; GO:0031105; GO:0005940,GTP binding; GTPase activity; cell cycle; cell division; cellularization; germline ring canal; microtubule associated complex; positive regulation of apoptotic process; septin complex; septin ring,PF00735;,,,,,,,,,SEPT1_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065] comp142787_c0_seq13,2696,38.0564,0.42488277,0,0,,1.00E-116,Q5R481,Septin-7,Septin-7,GO:0005525; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0016476; GO:0031105; GO:0005819,GTP binding; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; regulation of embryonic cell shape; septin complex; spindle,PF00735;,,,,,,,,,SEPT7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq14,2658,38.1866,0.46941208,0,0,,1.00E-158,P42207,Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),GO:0005525; GO:0003924; GO:0007049; GO:0051301; GO:0007349; GO:0045172; GO:0005875; GO:0043065; GO:0031105; GO:0005940,GTP binding; GTPase activity; cell cycle; cell division; cellularization; germline ring canal; microtubule associated complex; positive regulation of apoptotic process; septin complex; septin ring,PF00735;,0,CHOYP_LOC100372339.1.2,,,,,,,SEPT1_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065] comp142787_c0_seq15,2682,37.8822,0.43095342,0,0,,4.00E-156,Q5BKN4,Septin-2A,Septin-2A,GO:0005525; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0005737; GO:0030496; GO:0007067; GO:0031105; GO:0007224; GO:0005819,GTP binding; cell division; cilium assembly; cilium membrane; cleavage furrow; cytoplasm; midbody; mitosis; septin complex; smoothened signaling pathway; spindle,PF00735;,,,,,,,,,SEP2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq16,2451,39.6165,0.46272096,0,0,,4.00E-161,Q91Y81,Septin-2 (Vascular endothelial cell specific protein 11),Septin-2 (Vascular endothelial cell specific protein 11),GO:0005525; GO:0003924; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0000145; GO:0030496; GO:0007067; GO:0031175; GO:0048471; GO:0031105; GO:0007224; GO:0005819,GTP binding; GTPase activity; cell division; cilium assembly; cilium membrane; cleavage furrow; exocyst; midbody; mitosis; neuron projection development; perinuclear region of cytoplasm; septin complex; smoothened signaling pathway; spindle,PF00735;,5.00E-18,CHOYP_LOC373275.4.7,,,,,,,SEPT2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq17,2674,38.0703,0.45890524,0,0,,7.00E-161,Q91Y81,Septin-2 (Vascular endothelial cell specific protein 11),Septin-2 (Vascular endothelial cell specific protein 11),GO:0005525; GO:0003924; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0000145; GO:0030496; GO:0007067; GO:0031175; GO:0048471; GO:0031105; GO:0007224; GO:0005819,GTP binding; GTPase activity; cell division; cilium assembly; cilium membrane; cleavage furrow; exocyst; midbody; mitosis; neuron projection development; perinuclear region of cytoplasm; septin complex; smoothened signaling pathway; spindle,PF00735;,,,,,,,,,SEPT2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq18,2436,39.491,0.45768264,0,0,,1.00E-159,P42207,Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),GO:0005525; GO:0003924; GO:0007049; GO:0051301; GO:0007349; GO:0045172; GO:0005875; GO:0043065; GO:0031105; GO:0005940,GTP binding; GTPase activity; cell cycle; cell division; cellularization; germline ring canal; microtubule associated complex; positive regulation of apoptotic process; septin complex; septin ring,PF00735;,,,,,,,,,SEPT1_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065] comp142787_c0_seq19,2458,39.3816,0.42459699,0,0,,1.00E-74,Q5R8U3,Septin-11,Septin-11,GO:0005525; GO:0030424; GO:0007049; GO:0051301; GO:0030054; GO:0043197; GO:0031105; GO:0045202,GTP binding; axon; cell cycle; cell division; cell junction; dendritic spine; septin complex; synapse,PF00735;,2.00E-42,CHOYP_SEPT5.2.2,,,,,,,SEP11_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell cycle [GO:0007049]; cell division [GO:0051301] comp142787_c0_seq2,2672,38.0988,0.46917242,0,0,,3.00E-160,Q91Y81,Septin-2 (Vascular endothelial cell specific protein 11),Septin-2 (Vascular endothelial cell specific protein 11),GO:0005525; GO:0003924; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0000145; GO:0030496; GO:0007067; GO:0031175; GO:0048471; GO:0031105; GO:0007224; GO:0005819,GTP binding; GTPase activity; cell division; cilium assembly; cilium membrane; cleavage furrow; exocyst; midbody; mitosis; neuron projection development; perinuclear region of cytoplasm; septin complex; smoothened signaling pathway; spindle,PF00735;,0,CHOYP_LOC100372339.1.2,,,,,,,SEPT2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq20,2740,38.3212,0.46234637,0,0,,9.00E-117,O55131,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0043679; GO:0005938; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0005634; GO:0051291; GO:0016476; GO:0031105; GO:0005819; GO:0001725; GO:0045202,GTP binding; axon terminus; cell cortex; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; nucleus; protein heterooligomerization; regulation of embryonic cell shape; septin complex; spindle; stress fiber; synapse,PF00735;,,,,,,,,,SEPT7_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq22,2446,39.3295,0.41717528,0,0,,7.00E-117,Q9WVC0,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0016020; GO:0030496; GO:0007067; GO:0016476; GO:0031105; GO:0005819,GTP binding; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; membrane; midbody; mitosis; regulation of embryonic cell shape; septin complex; spindle,PF00735;,,,,,,,,,SEPT7_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq23,2424,39.4389,0.45049835,0,0,,6.00E-162,Q91Y81,Septin-2 (Vascular endothelial cell specific protein 11),Septin-2 (Vascular endothelial cell specific protein 11),GO:0005525; GO:0003924; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0000145; GO:0030496; GO:0007067; GO:0031175; GO:0048471; GO:0031105; GO:0007224; GO:0005819,GTP binding; GTPase activity; cell division; cilium assembly; cilium membrane; cleavage furrow; exocyst; midbody; mitosis; neuron projection development; perinuclear region of cytoplasm; septin complex; smoothened signaling pathway; spindle,PF00735;,0,CHOYP_LOC100372339.1.2,,,,,,,SEPT2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq24,2724,38.3627,0.47409906,0,0,,4.00E-157,P42207,Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),GO:0005525; GO:0003924; GO:0007049; GO:0051301; GO:0007349; GO:0045172; GO:0005875; GO:0043065; GO:0031105; GO:0005940,GTP binding; GTPase activity; cell cycle; cell division; cellularization; germline ring canal; microtubule associated complex; positive regulation of apoptotic process; septin complex; septin ring,PF00735;,,,,,,,,,SEPT1_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065] comp142787_c0_seq26,2712,38.3112,0.46737679,0,0,,8.00E-117,O55131,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0043679; GO:0005938; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0005634; GO:0051291; GO:0016476; GO:0031105; GO:0005819; GO:0001725; GO:0045202,GTP binding; axon terminus; cell cortex; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; nucleus; protein heterooligomerization; regulation of embryonic cell shape; septin complex; spindle; stress fiber; synapse,PF00735;,,,,,,,,,SEPT7_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq3,2708,38.1093,0.43205748,0,0,,,,,,,,,0,CHOYP_LOC100372339.2.2,,,,,,,,, comp142787_c0_seq4,2502,39.6483,0.46272834,0,0,,1.00E-117,O55131,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0043679; GO:0005938; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0005634; GO:0051291; GO:0016476; GO:0031105; GO:0005819; GO:0001725; GO:0045202,GTP binding; axon terminus; cell cortex; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; nucleus; protein heterooligomerization; regulation of embryonic cell shape; septin complex; spindle; stress fiber; synapse,PF00735;,6.00E-18,CHOYP_LOC373275.4.7,,,,,,,SEPT7_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq5,2738,38.2761,0.4738755,0,0,,4.00E-86,P39826,Cell division control protein 3,Cell division control protein 3,GO:0005525; GO:0007049; GO:0051301; GO:0005935; GO:0031105,GTP binding; cell cycle; cell division; cellular bud neck; septin complex,PF00735;,,,,,,,,,CDC3_CANAX,Candida albicans (Yeast),cell cycle [GO:0007049]; cell division [GO:0051301] comp142787_c0_seq6,2752,38.2994,0.47064971,0,0,,7.00E-117,O55131,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0043679; GO:0005938; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0005634; GO:0051291; GO:0016476; GO:0031105; GO:0005819; GO:0001725; GO:0045202,GTP binding; axon terminus; cell cortex; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; nucleus; protein heterooligomerization; regulation of embryonic cell shape; septin complex; spindle; stress fiber; synapse,PF00735;,,,,,,,,,SEPT7_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476] comp142787_c0_seq7,2646,38.133,0.46241689,0,0,,5.00E-161,Q91Y81,Septin-2 (Vascular endothelial cell specific protein 11),Septin-2 (Vascular endothelial cell specific protein 11),GO:0005525; GO:0003924; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0000145; GO:0030496; GO:0007067; GO:0031175; GO:0048471; GO:0031105; GO:0007224; GO:0005819,GTP binding; GTPase activity; cell division; cilium assembly; cilium membrane; cleavage furrow; exocyst; midbody; mitosis; neuron projection development; perinuclear region of cytoplasm; septin complex; smoothened signaling pathway; spindle,PF00735;,0,CHOYP_LOC100372339.1.2,,,,,,,SEPT2_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] comp142787_c0_seq8,2686,38.1236,0.46587662,0,0,,1.00E-158,P42207,Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),Septin-1 (DIFF6 protein homolog) (Protein innocent bystander),GO:0005525; GO:0003924; GO:0007049; GO:0051301; GO:0007349; GO:0045172; GO:0005875; GO:0043065; GO:0031105; GO:0005940,GTP binding; GTPase activity; cell cycle; cell division; cellularization; germline ring canal; microtubule associated complex; positive regulation of apoptotic process; septin complex; septin ring,PF00735;,6.00E-18,CHOYP_SEPT7.1.1,4.00E-43,ruditapes2_c1769,,,,,SEPT1_DROME,Drosophila melanogaster (Fruit fly),cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065] comp142787_c0_seq9,2726,38.1511,0.46878265,0,0,,8.00E-117,O55131,Septin-7 (CDC10 protein homolog),Septin-7 (CDC10 protein homolog),GO:0005525; GO:0043679; GO:0005938; GO:0051301; GO:0035085; GO:0060271; GO:0032154; GO:0000777; GO:0030496; GO:0007067; GO:0005634; GO:0051291; GO:0016476; GO:0031105; GO:0005819; GO:0001725; GO:0045202,GTP binding; axon terminus; cell cortex; cell division; cilium axoneme; cilium morphogenesis; cleavage furrow; condensed chromosome kinetochore; midbody; mitosis; nucleus; protein heterooligomerization; regulation of embryonic cell shape; septin complex; spindle; stress fiber; synapse,PF00735;,,,,,,,,,SEPT7_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476] comp142788_c3_seq1,1551,44.5519,0.98382312,0,0,,5.00E-17,Q60644,Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor subfamily 1 group H member 2) (Retinoid X receptor-interacting protein No.15) (Ubiquitously-expressed nuclear receptor),Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor subfamily 1 group H member 2) (Retinoid X receptor-interacting protein No.15) (Ubiquitously-expressed nuclear receptor),GO:0003677; GO:0044255; GO:0042632; GO:0005737; GO:0004879; GO:0010887; GO:0032369; GO:0048550; GO:0045861; GO:0000122; GO:0005634; GO:0032270; GO:0010875; GO:0045723; GO:0090108; GO:0010884; GO:0051006; GO:0090187; GO:0090340; GO:0045944; GO:0010867; GO:0048384; GO:0046965; GO:0043565; GO:0001133; GO:0003707; GO:0008270,DNA binding; cellular lipid metabolic process; cholesterol homeostasis; cytoplasm; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; negative regulation of cholesterol storage; negative regulation of lipid transport; negative regulation of pinocytosis; negative regulation of proteolysis; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of cellular protein metabolic process; positive regulation of cholesterol efflux; positive regulation of fatty acid biosynthetic process; positive regulation of high-density lipoprotein particle assembly; positive regulation of lipid storage; positive regulation of lipoprotein lipase activity; positive regulation of pancreatic juice secretion; positive regulation of secretion of lysosomal enzymes; positive regulation of transcription from RNA polymerase II promoter; positive regulation of triglyceride biosynthetic process; retinoic acid receptor signaling pathway; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR1H2_MOUSE,Mus musculus (Mouse),"cellular lipid metabolic process [GO:0044255]; cholesterol homeostasis [GO:0042632]; lipid homeostasis [GO:0055088]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of lipid transport [GO:0032369]; negative regulation of pinocytosis [GO:0048550]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of high-density lipoprotein particle assembly [GO:0090108]; positive regulation of lipid storage [GO:0010884]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of pancreatic juice secretion [GO:0090187]; positive regulation of secretion of lysosomal enzymes [GO:0090340]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cholesterol homeostasis [GO:2000188]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]" comp142788_c3_seq3,1859,44.5401,1.08552663,5,499,,6.00E-27,Q60674,Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),GO:0003677; GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0004887; GO:0008270,DNA binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR1D2_MOUSE,Mus musculus (Mouse),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp142788_c3_seq5,2907,39.8349,0.5322093,2015,50,,6.00E-69,D3Z3C6,AN1-type zinc finger protein 4 (AN1-type zinc finger and ubiquitin domain-containing protein-like 1),AN1-type zinc finger protein 4 (AN1-type zinc finger and ubiquitin domain-containing protein-like 1),GO:0008270,zinc ion binding,PF00240;PF01428;,3.00E-110,CHOYP_LOC100051390.1.1,,,,,,,ZFAN4_MOUSE,Mus musculus (Mouse), comp142789_c0_seq1,2722,42.4688,0.49510898,144,1047,,0,Q15477,Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP),Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP),GO:0005524; GO:0004004; GO:0003723; GO:0055087; GO:0005634,ATP binding; ATP-dependent RNA helicase activity; RNA binding; Ski complex; nucleus,PF00270;PF08148;PF00271;PF13234;,0,CHOYP_SKIV2L.4.4,,,,,,,SKIV2_HUMAN,Homo sapiens (Human),RNA catabolic process [GO:0006401] comp142790_c0_seq1,2047,34.1964,0.9094739,209,807,,2.00E-63,B3LYP1,Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20),Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20),GO:0006370; GO:0000339; GO:0031047; GO:0045292; GO:0005846; GO:0000166; GO:0005634,"7-methylguanosine mRNA capping; RNA cap binding; gene silencing by RNA; mRNA cis splicing, via spliceosome; nuclear cap binding complex; nucleotide binding; nucleus",PF00076;,,,,,,,,,NCBP2_DROAN,Drosophila ananassae (Fruit fly),"7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]" comp142790_c0_seq3,2018,34.3905,0.91323053,216,785,,1.00E-63,B3LYP1,Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20),Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20),GO:0006370; GO:0000339; GO:0031047; GO:0045292; GO:0005846; GO:0000166; GO:0005634,"7-methylguanosine mRNA capping; RNA cap binding; gene silencing by RNA; mRNA cis splicing, via spliceosome; nuclear cap binding complex; nucleotide binding; nucleus",PF00076;,7.00E-54,CHOYP_NCBP2.1.1,,,,,,,NCBP2_DROAN,Drosophila ananassae (Fruit fly),"7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]" comp142791_c0_seq2,2381,44.6451,0.5356965,16,6,,4.00E-107,P26013,Integrin beta-8,Integrin beta-8,GO:0007160; GO:0008305; GO:0007229; GO:0007275; GO:0004872,cell-matrix adhesion; integrin complex; integrin-mediated signaling pathway; multicellular organismal development; receptor activity,PF07974;PF00362;,3.00E-52,CHOYP_LOC657674.1.1,,,,,,,ITB8_RABIT,Oryctolagus cuniculus (Rabbit),cartilage development [GO:0051216]; cell-matrix adhesion [GO:0007160]; ganglioside metabolic process [GO:0001573]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628] comp142791_c0_seq3,2381,44.6031,0.53443643,13,37,,0,P11584,Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C),Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C),GO:0007015; GO:0007475; GO:0007411; GO:0009925; GO:0007298; GO:0016339; GO:0016340; GO:0050839; GO:0031252; GO:0007417; GO:0008340; GO:0007391; GO:0035001; GO:0007427; GO:0007629; GO:0005925; GO:0007377; GO:0030718; GO:0035099; GO:0007157; GO:0048803; GO:0008305; GO:0007229; GO:0007508; GO:0016328; GO:0035160; GO:0007494; GO:0016203; GO:0030336; GO:0003344; GO:0004872; GO:0008360; GO:0051492; GO:0007431; GO:0007608; GO:0006930; GO:0007426; GO:0007601,"actin filament organization; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; basal plasma membrane; border follicle cell migration; calcium-dependent cell-cell adhesion; calcium-dependent cell-matrix adhesion; cell adhesion molecule binding; cell leading edge; central nervous system development; determination of adult lifespan; dorsal closure; dorsal trunk growth, open tracheal system; epithelial cell migration, open tracheal system; flight behavior; focal adhesion; germ-band extension; germ-line stem cell maintenance; hemocyte migration; heterophilic cell-cell adhesion; imaginal disc-derived male genitalia morphogenesis; integrin complex; integrin-mediated signaling pathway; larval heart development; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; midgut development; muscle attachment; negative regulation of cell migration; pericardium morphogenesis; receptor activity; regulation of cell shape; regulation of stress fiber assembly; salivary gland development; sensory perception of smell; substrate-dependent cell migration, cell extension; tracheal outgrowth, open tracheal system; visual perception",PF07974;PF08725;PF07965;PF00362;,,,,,,,,,ITBX_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-dependent cell-matrix adhesion [GO:0016340]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; central nervous system development [GO:0007417]; central nervous system morphogenesis [GO:0021551]; determination of adult lifespan [GO:0008340]; dorsal closure [GO:0007391]; dorsal trunk growth, open tracheal system [GO:0035001]; epithelial cell migration, open tracheal system [GO:0007427]; flight behavior [GO:0007629]; germ-band extension [GO:0007377]; germ-line stem cell population maintenance [GO:0030718]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; integrin-mediated signaling pathway [GO:0007229]; larval heart development [GO:0007508]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; negative regulation of cell migration [GO:0030336]; pericardium morphogenesis [GO:0003344]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; tracheal outgrowth, open tracheal system [GO:0007426]; visual perception [GO:0007601]" comp142791_c0_seq4,963,42.9907,0.57076606,0,0,,2.00E-16,Q09062,Integrin beta-2 (Fragment),Integrin beta-2 (Fragment),GO:0007155; GO:0016021; GO:0007229,cell adhesion; integral to membrane; integrin-mediated signaling pathway,PF00362;,8.00E-49,CHOYP_LOC657674.1.1,,,,,,,ITB2_XENLA,Xenopus laevis (African clawed frog),cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229] comp142797_c0_seq1,2203,44.7118,0.42316338,848,3600,,4.00E-33,Q99181,Protein HSH49,Protein HSH49,GO:0003723; GO:0005686; GO:0071004; GO:0000398; GO:0000166,"RNA binding; U2 snRNP; U2-type prespliceosome; mRNA splicing, via spliceosome; nucleotide binding",PF00076;,,,,,,,,,HSH49_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"mRNA splicing, via spliceosome [GO:0000398]" comp142797_c0_seq2,1562,50.7682,0.37603891,129,847,,8.00E-134,Q15427,Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (SF3b50) (Spliceosome-associated protein 49) (SAP 49),Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (SF3b50) (Spliceosome-associated protein 49) (SAP 49),GO:0003723; GO:0005689; GO:0000398; GO:0005654; GO:0000166,"RNA binding; U12-type spliceosomal complex; mRNA splicing, via spliceosome; nucleoplasm; nucleotide binding",PF00076;,2.00E-148,CHOYP_SF3B4.1.1,,,,,,,SF3B4_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" comp142798_c0_seq1,5455,35.6737,0.73955739,3504,11604,,4.00E-36,Q03049,Putative uncharacterized oxidoreductase YDR541C (EC 1.1.1.-),Putative uncharacterized oxidoreductase YDR541C (EC 1.1.1.-),GO:0004090; GO:0044237; GO:0050662,carbonyl reductase (NADPH) activity; cellular metabolic process; coenzyme binding,PF01370;,4.00E-112,CHOYP_LOC100376187.2.2,,,,,,,YD541_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),response to furfural [GO:1901426] comp142799_c0_seq1,2324,43.4165,0.86319273,430,2165,,0,B1WAZ6,Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],GO:0016023; GO:0004622; GO:0046872; GO:0004623; GO:0009395,cytoplasmic membrane-bounded vesicle; lysophospholipase activity; metal ion binding; phospholipase A2 activity; phospholipid catabolic process,PF00168;PF01735;,8.00E-22,CHOYP_PGH2.2.2,3.00E-19,ruditapes_c10591,,,,,PA24A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),phospholipid catabolic process [GO:0009395] comp142799_c0_seq2,774,42.3773,0.8727492,2,8,,1.00E-08,Q08108,Lysophospholipase 3 (EC 3.1.1.5) (Phospholipase B 3),Lysophospholipase 3 (EC 3.1.1.5) (Phospholipase B 3),GO:0031225; GO:0005576; GO:0004622; GO:0046488; GO:0006660; GO:0005886,anchored to membrane; extracellular region; lysophospholipase activity; phosphatidylinositol metabolic process; phosphatidylserine catabolic process; plasma membrane,PF01735;,4.00E-14,CHOYP_PA24A.2.3,,,,,,,PLB3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),phosphatidylinositol metabolic process [GO:0046488]; phosphatidylserine catabolic process [GO:0006660] comp142799_c0_seq4,3630,40.4132,0.49465299,3471,9228,,0,P29190,Phosphoenolpyruvate carboxykinase [GTP] (PEPCK) (EC 4.1.1.32) (Phosphoenolpyruvate carboxylase),Phosphoenolpyruvate carboxykinase [GTP] (PEPCK) (EC 4.1.1.32),GO:0005525; GO:0006094; GO:0046872; GO:0004613,GTP binding; gluconeogenesis; metal ion binding; phosphoenolpyruvate carboxykinase (GTP) activity,PF00821;,0,CHOYP_PCKG.2.2,1.00E-51,ruditapes_c29485,,,,,PCKG_HAECO,Haemonchus contortus (Barber pole worm),gluconeogenesis [GO:0006094] comp142800_c0_seq1,1577,40.2663,0.51556012,28,124,,1.00E-97,Q9M8D3,"Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase)","Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)",GO:0006189; GO:0005524; GO:0009507; GO:0006541; GO:0005739; GO:0004642,'de novo' IMP biosynthetic process; ATP binding; chloroplast; glutamine metabolic process; mitochondrion; phosphoribosylformylglycinamidine synthase activity,PF02769;,,,,,,,,,PUR4_ARATH,Arabidopsis thaliana (Mouse-ear cress),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156] comp142800_c0_seq2,1759,39.3974,0.49382732,104,154,,1.00E-95,Q5SUR0,Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase),Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase),GO:0006189; GO:0005524; GO:0005737; GO:0006541; GO:0004642,'de novo' IMP biosynthetic process; ATP binding; cytoplasm; glutamine metabolic process; phosphoribosylformylglycinamidine synthase activity,PF02769;,1.00E-68,CHOYP_BRAFLDRAFT_278091.1.1,,,,,,,PUR4_MOUSE,Mus musculus (Mouse),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; response to drug [GO:0042493]; ribonucleoside monophosphate biosynthetic process [GO:0009156] comp142801_c2_seq1,1698,37.1614,0.55169074,3,21,,4.00E-09,Q8NI35,InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions),InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions),GO:0016324; GO:0035556; GO:0048471; GO:0005886; GO:0005923; GO:0070830,apical plasma membrane; intracellular signal transduction; perinuclear region of cytoplasm; plasma membrane; tight junction; tight junction assembly,PF09045;PF00595;,,,,,,,,,INADL_HUMAN,Homo sapiens (Human),bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556] comp142801_c2_seq2,2290,34.8035,0.53881907,12,119,,7.00E-14,Q91XM9,Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),GO:0030054; GO:0044224; GO:0010923; GO:0014069; GO:0045211; GO:0019233; GO:0007268,cell junction; juxtaparanode region of axon; negative regulation of phosphatase activity; postsynaptic density; postsynaptic membrane; sensory perception of pain; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,,,,,,,,,DLG2_MOUSE,Mus musculus (Mouse),chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233] comp142801_c2_seq3,3176,34.6977,0.52405512,155,521,,5.00E-08,P97879,Glutamate receptor-interacting protein 1 (GRIP-1) (AMPA receptor-interacting protein GRIP1),Glutamate receptor-interacting protein 1 (GRIP-1) (AMPA receptor-interacting protein GRIP1),GO:0030054; GO:0005789; GO:0007399; GO:0043025; GO:0014069; GO:0045211; GO:0015031,cell junction; endoplasmic reticulum membrane; nervous system development; neuronal cell body; postsynaptic density; postsynaptic membrane; protein transport,PF00595;,,,,,,,,,GRIP1_RAT,Rattus norvegicus (Rat),dendrite development [GO:0016358]; nervous system development [GO:0007399]; protein transport [GO:0015031] comp142801_c2_seq5,2272,34.9912,0.53757217,0,0,,3.00E-98,Q792I0,Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3),Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3),GO:0016323; GO:0005911; GO:0006887; GO:0043005; GO:0007269; GO:0014069; GO:0045211; GO:0015031; GO:0045202; GO:0005923,basolateral plasma membrane; cell-cell junction; exocytosis; neuron projection; neurotransmitter secretion; postsynaptic density; postsynaptic membrane; protein transport; synapse; tight junction,PF02828;PF00595;,1.00E-94,CHOYP_LOC100329062.1.2,,,,,,,LIN7C_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031] comp142801_c2_seq6,2281,35.8615,0.50890843,0,24,,3.00E-98,Q792I0,Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3),Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3),GO:0016323; GO:0005911; GO:0006887; GO:0043005; GO:0007269; GO:0014069; GO:0045211; GO:0015031; GO:0045202; GO:0005923,basolateral plasma membrane; cell-cell junction; exocytosis; neuron projection; neurotransmitter secretion; postsynaptic density; postsynaptic membrane; protein transport; synapse; tight junction,PF02828;PF00595;,1.00E-94,CHOYP_LOC100329062.1.2,4.00E-74,ruditapes_c10469,,,,,LIN7C_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031] comp142802_c0_seq2,1120,43.4821,0.4728206,0,0,,,,,,,,,3.00E-11,CHOYP_LOC100708199.1.6,,,,,,,,, comp142802_c0_seq3,1567,42.8845,0.44469672,4,6,,,,,,,,,8.00E-20,CHOYP_contig_016287,,,,,,,,, comp142805_c2_seq1,5522,51.648,0.63733547,58,169,,5.00E-39,P12107,Collagen alpha-1(XI) chain,Collagen alpha-1(XI) chain,GO:0001502; GO:0002063; GO:0030574; GO:0030199; GO:0005592; GO:0050910; GO:0048704; GO:0005788; GO:0050840; GO:0022617; GO:0005201; GO:0042472; GO:0046872; GO:0030674; GO:0006029; GO:0035989; GO:0055010; GO:0007601,"cartilage condensation; chondrocyte development; collagen catabolic process; collagen fibril organization; collagen type XI; detection of mechanical stimulus involved in sensory perception of sound; embryonic skeletal system morphogenesis; endoplasmic reticulum lumen; extracellular matrix binding; extracellular matrix disassembly; extracellular matrix structural constituent; inner ear morphogenesis; metal ion binding; protein binding, bridging; proteoglycan metabolic process; tendon development; ventricular cardiac muscle tissue morphogenesis; visual perception",PF01410;PF01391;,5.00E-29,CHOYP_LOC659206.6.6,,,,,,,COBA1_HUMAN,Homo sapiens (Human),cartilage condensation [GO:0001502]; chondrocyte development [GO:0002063]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601] comp142805_c2_seq2,4706,55.0786,0.60294281,1,0,,3.00E-39,P12107,Collagen alpha-1(XI) chain,Collagen alpha-1(XI) chain,GO:0001502; GO:0002063; GO:0030574; GO:0030199; GO:0005592; GO:0050910; GO:0048704; GO:0005788; GO:0050840; GO:0022617; GO:0005201; GO:0042472; GO:0046872; GO:0030674; GO:0006029; GO:0035989; GO:0055010; GO:0007601,"cartilage condensation; chondrocyte development; collagen catabolic process; collagen fibril organization; collagen type XI; detection of mechanical stimulus involved in sensory perception of sound; embryonic skeletal system morphogenesis; endoplasmic reticulum lumen; extracellular matrix binding; extracellular matrix disassembly; extracellular matrix structural constituent; inner ear morphogenesis; metal ion binding; protein binding, bridging; proteoglycan metabolic process; tendon development; ventricular cardiac muscle tissue morphogenesis; visual perception",PF01410;PF01391;,4.00E-29,CHOYP_LOC659206.6.6,,,,,,,COBA1_HUMAN,Homo sapiens (Human),cartilage condensation [GO:0001502]; chondrocyte development [GO:0002063]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601] comp142805_c2_seq3,5165,53.4172,0.62443563,2,8,,3.00E-16,Q05722,Collagen alpha-1(IX) chain,Collagen alpha-1(IX) chain,GO:0005581; GO:0003417; GO:0046872; GO:0001894,collagen; growth plate cartilage development; metal ion binding; tissue homeostasis,PF01391;,,,,,,,,,CO9A1_MOUSE,Mus musculus (Mouse),cartilage development [GO:0051216]; growth plate cartilage development [GO:0003417]; tissue homeostasis [GO:0001894] comp142806_c0_seq2,1324,40.4079,0.38892172,0,0,,4.00E-58,Q767L8,Mediator of DNA damage checkpoint protein 1,Mediator of DNA damage checkpoint protein 1,GO:0006281; GO:0007049; GO:0005694; GO:0005634,DNA repair; cell cycle; chromosome; nucleus,PF00498;PF16770;,2.00E-14,CHOYP_LOC582503.1.1,,,,,,,MDC1_PIG,Sus scrofa (Pig),cell cycle [GO:0007049]; DNA repair [GO:0006281] comp142806_c0_seq4,2238,40.0357,0.34651836,15,46,,9.00E-26,Q6NZQ4,PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),GO:0030330; GO:0006310; GO:0006281; GO:0060612; GO:0060717; GO:0043542; GO:0051568; GO:0035097; GO:0016363; GO:0000416; GO:0051571; GO:0035066; GO:0045830; GO:0031398; GO:0060261; GO:0006974; GO:0010212; GO:0006351; GO:0001570,"DNA damage response, signal transduction by p53 class mediator; DNA recombination; DNA repair; adipose tissue development; chorion development; endothelial cell migration; histone H3-K4 methylation; histone methyltransferase complex; nuclear matrix; positive regulation of histone H3-K36 methylation; positive regulation of histone H3-K4 methylation; positive regulation of histone acetylation; positive regulation of isotype switching; positive regulation of protein ubiquitination; positive regulation of transcription initiation from RNA polymerase II promoter; response to DNA damage stimulus; response to ionizing radiation; transcription, DNA-dependent; vasculogenesis",PF00533;PF12738;PF16770;,,,,,,,,,PAXI1_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; cellular response to DNA damage stimulus [GO:0006974]; chorion development [GO:0060717]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K36 methylation [GO:0000416]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]" comp142806_c0_seq8,1279,40.7349,0.39675301,0,0,,2.00E-58,Q767L8,Mediator of DNA damage checkpoint protein 1,Mediator of DNA damage checkpoint protein 1,GO:0006281; GO:0007049; GO:0005694; GO:0005634,DNA repair; cell cycle; chromosome; nucleus,PF00498;PF16770;,2.00E-14,CHOYP_LOC582503.1.1,,,,,,,MDC1_PIG,Sus scrofa (Pig),cell cycle [GO:0007049]; DNA repair [GO:0006281] comp142807_c2_seq1,745,38.3893,0.37449867,121,922,,5.00E-17,O08836,Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit),Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit),GO:0042113; GO:0005737; GO:0043066; GO:0043154; GO:0035308; GO:0032873; GO:0000122; GO:0035306; GO:0045944; GO:0008601; GO:0060632; GO:0070555; GO:0034612,B cell activation; cytoplasm; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of protein dephosphorylation; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dephosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein phosphatase type 2A regulator activity; regulation of microtubule-based movement; response to interleukin-1; response to tumor necrosis factor,PF04177;,,,,,,,,,IGBP1_RAT,Rattus norvegicus (Rat),B cell activation [GO:0042113]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of dephosphorylation [GO:0035303]; regulation of microtubule-based movement [GO:0060632]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612] comp142807_c3_seq1,821,37.8806,0.51572772,144,1201,,1.00E-11,P78318,Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16),Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16),GO:0042113; GO:0005737; GO:0043066; GO:0043154; GO:0035308; GO:0032873; GO:0000122; GO:0035306; GO:0045944; GO:0008601; GO:0060632; GO:0070555; GO:0034612; GO:0007165,B cell activation; cytoplasm; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of protein dephosphorylation; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dephosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein phosphatase type 2A regulator activity; regulation of microtubule-based movement; response to interleukin-1; response to tumor necrosis factor; signal transduction,PF04177;,7.00E-24,CHOYP_LOC100694272.1.1,,,,,,,IGBP1_HUMAN,Homo sapiens (Human),B cell activation [GO:0042113]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of microtubule-based movement [GO:0060632]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165] comp142809_c0_seq1,2461,38.6022,0.41051092,28,144,,3.00E-19,E5A2Z3,Nucleolar protein 9 (Pumilio domain-containing protein NOP9),Nucleolar protein 9 (Pumilio domain-containing protein NOP9),GO:0003723; GO:0005730; GO:0006364,RNA binding; nucleolus; rRNA processing,,,,,,,,,,NOP9_LEPMJ,Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam),"endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; ribosomal small subunit export from nucleus [GO:0000056]" comp142809_c0_seq2,2480,38.4677,0.42079383,13,261,,1.00E-66,Q86U38,Nucleolar protein 9,Nucleolar protein 9,GO:0003723,RNA binding,,,,,,,,,,NOP9_HUMAN,Homo sapiens (Human), comp142811_c0_seq2,1118,35.5098,0.54110295,143,313,,3.00E-92,Q9BPU9,B9 domain-containing protein 2 (MKS1-related protein 2),B9 domain-containing protein 2 (MKS1-related protein 2),GO:0036038; GO:0005813; GO:0042384; GO:0035085; GO:0005829; GO:0043015; GO:0016020; GO:0005932; GO:0000278; GO:0005634,TCTN-B9D complex; centrosome; cilium assembly; cilium axoneme; cytosol; gamma-tubulin binding; membrane; microtubule basal body; mitotic cell cycle; nucleus,PF07162;,4.00E-111,CHOYP_BRAFLDRAFT_87511.1.1,,,1.00E-109,BQ427333.p.cg.6,7,,B9D2_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; sister chromatid cohesion [GO:0007062] comp142816_c0_seq10,2392,40.0502,0.92167383,0,18,,7.00E-105,Q9M0X9,4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6),4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6),GO:0005524; GO:0004321; GO:0009695; GO:0016874; GO:0031408; GO:0005777,ATP binding; fatty-acyl-CoA synthase activity; jasmonic acid biosynthetic process; ligase activity; oxylipin biosynthetic process; peroxisome,PF00501;PF13193;,,,,,,,,,4CLL7_ARATH,Arabidopsis thaliana (Mouse-ear cress),jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408] comp142816_c0_seq14,2212,40.0542,0.84989878,0,0,,6.00E-59,P31686,4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment),4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL1_SOYBN,Glycine max (Soybean) (Glycine hispida),phenylpropanoid metabolic process [GO:0009698] comp142816_c0_seq3,2175,40.1379,0.82687007,0,0,,6.00E-59,P31686,4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment),4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL1_SOYBN,Glycine max (Soybean) (Glycine hispida),phenylpropanoid metabolic process [GO:0009698] comp142816_c0_seq4,2293,40.7327,0.86542159,0,0,,2.00E-28,Q9R9J1,Mycosubtilin synthase subunit A (EC 2.3.1.-) [Includes: Glutamate-1-semialdehyde aminotransferase (GSA-AT); ATP-dependent asparagine adenylase 1 (AsnA 1) (Asparagine activase 1)],Mycosubtilin synthase subunit A (EC 2.3.1.-) [Includes: Glutamate-1-semialdehyde aminotransferase (GSA-AT); ATP-dependent asparagine adenylase 1 (AsnA 1) (Asparagine activase 1)],GO:0017000; GO:0016874; GO:0031177; GO:0030170; GO:0008483,antibiotic biosynthetic process; ligase activity; phosphopantetheine binding; pyridoxal phosphate binding; transaminase activity,PF00202;PF00501;PF13193;PF00668;PF16197;PF00109;PF02801;PF00550;,,,,,,,,,MYCA_BACIU,Bacillus subtilis,antibiotic biosynthetic process [GO:0017000] comp142816_c0_seq5,2274,39.5339,0.88375932,0,0,,6.00E-24,Q9BEA2,"Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1) (XL-III) (Xenobiotic/medium-chain fatty acid:CoA ligase XL-3) (XM-ligase 3)","Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1) (XL-III) (Xenobiotic/medium-chain fatty acid:CoA ligase XL-3) (XM-ligase 3)",GO:0005524; GO:0005525; GO:0047760; GO:0006631; GO:0046872; GO:0005759,ATP binding; GTP binding; butyrate-CoA ligase activity; fatty acid metabolic process; metal ion binding; mitochondrial matrix,PF00501;PF13193;,,,,,,,,,ACSM1_BOVIN,Bos taurus (Bovine),fatty acid biosynthetic process [GO:0006633] comp142816_c0_seq6,2330,40.6438,0.88630402,0,0,,1.00E-74,P94547,Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain acyl-CoA synthetase),Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain acyl-CoA synthetase),GO:0005524; GO:0001676; GO:0004467,ATP binding; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,LCFA_BACSU,Bacillus subtilis (strain 168), comp142816_c0_seq7,2355,40.2123,0.89718219,0,0,,5.00E-105,Q9M0X9,4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6),4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6),GO:0005524; GO:0004321; GO:0009695; GO:0016874; GO:0031408; GO:0005777,ATP binding; fatty-acyl-CoA synthase activity; jasmonic acid biosynthetic process; ligase activity; oxylipin biosynthetic process; peroxisome,PF00501;PF13193;,,,,,,,,,4CLL7_ARATH,Arabidopsis thaliana (Mouse-ear cress),jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408] comp142816_c0_seq9,2237,39.6066,0.86129943,0,0,,1.00E-37,Q8GVF9,Putative 4-coumarate--CoA ligase-like 8 (EC 6.2.1.-),Putative 4-coumarate--CoA ligase-like 8 (EC 6.2.1.-),GO:0005524; GO:0016874,ATP binding; ligase activity,PF00501;PF13193;,,,,,,,,,4CLL8_ORYSJ,Oryza sativa subsp. japonica (Rice),metabolic process [GO:0008152] comp142817_c0_seq1,2072,39.334,0.39404373,20,111,,0,A7SXZ6,Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.-) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep),Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep),GO:0046872; GO:0008033,metal ion binding; tRNA processing,PF00814;,0,CHOYP_OSGEP.1.1,,,,,,,OSGEP_NEMVE,Nematostella vectensis (Starlet sea anemone),tRNA threonylcarbamoyladenosine modification [GO:0002949] comp142817_c0_seq2,2059,39.4852,0.40623161,33,156,,0,A7SXZ6,Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.-) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep),Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep),GO:0046872; GO:0008033,metal ion binding; tRNA processing,PF00814;,0,CHOYP_OSGEP.1.1,,,,,,,OSGEP_NEMVE,Nematostella vectensis (Starlet sea anemone),tRNA threonylcarbamoyladenosine modification [GO:0002949] comp142818_c1_seq1,2083,43.3989,0.57467304,0,0,,2.00E-19,O23052,Uncharacterized TPR repeat-containing protein At1g05150,Uncharacterized TPR repeat-containing protein At1g05150,GO:0005794; GO:0005509; GO:0005768; GO:0005886; GO:0009506; GO:0005802; GO:0008270,Golgi apparatus; calcium ion binding; endosome; plasma membrane; plasmodesma; trans-Golgi network; zinc ion binding,PF13414;,,,,,,,,,Y1515_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp142818_c1_seq12,2750,44.5455,0.45464535,0,0,,0,Q9M8Y0,Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT),Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT),GO:0007275; GO:0006493; GO:0016757,"multicellular organismal development; protein O-linked glycosylation; transferase activity, transferring glycosyl groups",PF13844;PF00515;PF13414;PF13176;PF13181;,0,CHOYP_OGT1.3.3,,,,,,,SEC_ARATH,Arabidopsis thaliana (Mouse-ear cress),multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493] comp142818_c1_seq14,3194,43.5817,0.51472659,0,0,,0,O15294,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),GO:0070688; GO:0006915; GO:0071300; GO:0005813; GO:0005829; GO:0008047; GO:0080182; GO:0043984; GO:0043981; GO:0043982; GO:0000123; GO:0005739; GO:0005547; GO:0048015; GO:0005886; GO:0030854; GO:0051571; GO:0045862; GO:0045944; GO:0016262; GO:0006493; GO:0035020; GO:0006110; GO:0046626; GO:0032868; GO:0007584,"MLL5-L complex; apoptotic process; cellular response to retinoic acid; centrosome; cytosol; enzyme activator activity; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex; mitochondrion; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of granulocyte differentiation; positive regulation of histone H3-K4 methylation; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation; regulation of Rac protein signal transduction; regulation of glycolysis; regulation of insulin receptor signaling pathway; response to insulin stimulus; response to nutrient",PF13844;PF00515;PF13414;PF13181;,,,,,,,,,OGT1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cellular response to toxic substance [GO:0097237]; circadian regulation of gene expression [GO:0032922]; forebrain development [GO:0030900]; glucosamine metabolic process [GO:0006041]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of cell death [GO:0060548]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotrimerization [GO:0070208]; protein homotrimerization [GO:0070207]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of Rac protein signal transduction [GO:0035020]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; signal transduction [GO:0007165] comp142818_c1_seq16,2274,43.0079,0.59240573,0,0,,3.00E-19,O23052,Uncharacterized TPR repeat-containing protein At1g05150,Uncharacterized TPR repeat-containing protein At1g05150,GO:0005794; GO:0005509; GO:0005768; GO:0005886; GO:0009506; GO:0005802; GO:0008270,Golgi apparatus; calcium ion binding; endosome; plasma membrane; plasmodesma; trans-Golgi network; zinc ion binding,PF13414;,,,,,,,,,Y1515_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp142818_c1_seq19,768,41.6667,0.66109291,0,0,,8.00E-57,P56558,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),GO:0006915; GO:0005829; GO:0080182; GO:0043984; GO:0043981; GO:0043982; GO:0000123; GO:0048029; GO:0042277; GO:0005547; GO:0048015; GO:0005886; GO:0045862; GO:0045944; GO:0016262; GO:0006493; GO:0070207; GO:0006110,"apoptotic process; cytosol; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex; monosaccharide binding; peptide binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation; protein homotrimerization; regulation of glycolysis",PF13844;PF00515;PF13414;PF13181;,,,,,,,,,OGT1_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; circadian regulation of gene expression [GO:0032922]; forebrain development [GO:0030900]; glucosamine metabolic process [GO:0006041]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of cell death [GO:0060548]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotrimerization [GO:0070208]; protein homotrimerization [GO:0070207]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110] comp142818_c1_seq2,2494,45.429,0.41210116,0,0,,0,Q9M8Y0,Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT),Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT),GO:0007275; GO:0006493; GO:0016757,"multicellular organismal development; protein O-linked glycosylation; transferase activity, transferring glycosyl groups",PF13844;PF00515;PF13414;PF13176;PF13181;,0,CHOYP_OGT1.3.3,,,,,,,SEC_ARATH,Arabidopsis thaliana (Mouse-ear cress),multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493] comp142818_c1_seq3,3669,44.6716,0.42638191,2,46,,0,O15294,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),GO:0070688; GO:0006915; GO:0071300; GO:0005813; GO:0005829; GO:0008047; GO:0080182; GO:0043984; GO:0043981; GO:0043982; GO:0000123; GO:0005739; GO:0005547; GO:0048015; GO:0005886; GO:0030854; GO:0051571; GO:0045862; GO:0045944; GO:0016262; GO:0006493; GO:0035020; GO:0006110; GO:0046626; GO:0032868; GO:0007584,"MLL5-L complex; apoptotic process; cellular response to retinoic acid; centrosome; cytosol; enzyme activator activity; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex; mitochondrion; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of granulocyte differentiation; positive regulation of histone H3-K4 methylation; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation; regulation of Rac protein signal transduction; regulation of glycolysis; regulation of insulin receptor signaling pathway; response to insulin stimulus; response to nutrient",PF13844;PF00515;PF13414;PF13181;,,,,,,,,,OGT1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cellular response to toxic substance [GO:0097237]; circadian regulation of gene expression [GO:0032922]; forebrain development [GO:0030900]; glucosamine metabolic process [GO:0006041]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of cell death [GO:0060548]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotrimerization [GO:0070208]; protein homotrimerization [GO:0070207]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of Rac protein signal transduction [GO:0035020]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; signal transduction [GO:0007165] comp142818_c1_seq4,817,45.6548,0.26362397,4,4,,,,,,,,,2.00E-100,CHOYP_OGT1.2.3,,,,,,,,, comp142818_c1_seq5,1688,43.4834,0.47711881,0,0,,1.00E-27,A8BFN4,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (GlOGT) (EC 2.4.1.255) (O-linked GlcNAc transferase) (O-linked N-acetylglucosaminyltransferase),UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (GlOGT) (EC 2.4.1.255) (O-linked GlcNAc transferase) (O-linked N-acetylglucosaminyltransferase),GO:0005737; GO:0005634; GO:0006486; GO:0016757,"cytoplasm; nucleus; protein glycosylation; transferase activity, transferring glycosyl groups",PF13844;PF00515;PF13374;PF13181;,,,,,,,,,OGT1_GIAIC,Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia),protein glycosylation [GO:0006486] comp142818_c1_seq6,2727,44.8111,0.45306274,0,0,,0,O18158,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (EC 2.4.1.-) (O-GlcNAc) (OGT),UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (EC 2.4.1.-) (O-GlcNAc) (OGT),GO:0006048; GO:0040024; GO:0005977; GO:0019915; GO:0005634; GO:0048471; GO:0016262; GO:0006493; GO:0006470; GO:0004722; GO:0000003,UDP-N-acetylglucosamine biosynthetic process; dauer larval development; glycogen metabolic process; lipid storage; nucleus; perinuclear region of cytoplasm; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation; protein dephosphorylation; protein serine/threonine phosphatase activity; reproduction,PF13844;PF00515;PF13374;PF13414;PF13181;,,,,,,,,,OGT1_CAEEL,Caenorhabditis elegans,dauer larval development [GO:0040024]; energy reserve metabolic process [GO:0006112]; glycogen metabolic process [GO:0005977]; lipid storage [GO:0019915]; protein dephosphorylation [GO:0006470]; protein O-linked glycosylation [GO:0006493]; reproduction [GO:0000003] comp142818_c1_seq7,2018,43.9049,0.54909188,0,0,,1.00E-17,Q8BRH0,Transmembrane and TPR repeat-containing protein 3,Transmembrane and TPR repeat-containing protein 3,GO:0060447; GO:0016021; GO:0048286; GO:0048747; GO:0009791; GO:0010468,bud outgrowth involved in lung branching; integral to membrane; lung alveolus development; muscle fiber development; post-embryonic development; regulation of gene expression,PF08409;PF00515;PF13174;PF13181;,,,,,,,,,TMTC3_MOUSE,Mus musculus (Mouse),bud outgrowth involved in lung branching [GO:0060447]; cell differentiation [GO:0030154]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; muscle fiber development [GO:0048747]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468] comp142818_c1_seq8,2559,44.9785,0.43287645,0,0,,0,P81436,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT),GO:0070688; GO:0006915; GO:0071300; GO:0005813; GO:0005829; GO:0008047; GO:0080182; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0005547; GO:0048015; GO:0005886; GO:0030854; GO:0051571; GO:0045862; GO:0045944; GO:0016262; GO:0006493; GO:0035020; GO:0006110; GO:0046626; GO:0032868,"MLL5-L complex; apoptotic process; cellular response to retinoic acid; centrosome; cytosol; enzyme activator activity; histone H3-K4 trimethylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of granulocyte differentiation; positive regulation of histone H3-K4 methylation; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation; regulation of Rac protein signal transduction; regulation of glycolysis; regulation of insulin receptor signaling pathway; response to insulin stimulus",PF13844;PF00515;PF13414;PF13181;,0,CHOYP_OGT1.3.3,,,,,,,OGT1_RABIT,Oryctolagus cuniculus (Rabbit),apoptotic process [GO:0006915]; cellular response to retinoic acid [GO:0071300]; circadian regulation of gene expression [GO:0032922]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of Rac protein signal transduction [GO:0035020]; response to insulin [GO:0032868] comp142818_c1_seq9,2251,43.3141,0.59012691,0,0,,3.00E-19,O23052,Uncharacterized TPR repeat-containing protein At1g05150,Uncharacterized TPR repeat-containing protein At1g05150,GO:0005794; GO:0005509; GO:0005768; GO:0005886; GO:0009506; GO:0005802; GO:0008270,Golgi apparatus; calcium ion binding; endosome; plasma membrane; plasmodesma; trans-Golgi network; zinc ion binding,PF13414;,,,,,,,,,Y1515_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp142824_c0_seq1,2141,27.7908,0.55671583,449,1230,,3.00E-23,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,4.00E-13,CHOYP_LOC100562878.2.2,8.00E-32,ruditapes_c19911,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp142826_c0_seq2,3357,41.0486,0.327398,267,354,,0,P47245,Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C),Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase),GO:0046872; GO:0004222; GO:0008233; GO:0006508,metal ion binding; metalloendopeptidase activity; peptidase activity; proteolysis,PF00675;PF05193;PF16187;,7.00E-37,CHOYP_NRDC.1.1,1.00E-45,ruditapes_c21358,,,,,NRDC_RAT,Rattus norvegicus (Rat),protein processing [GO:0016485] comp142829_c0_seq1,1560,43.8462,1.0171129,0,444,,2.00E-19,Q6P2Z3,Forkhead box protein I1 (FoxI1),Forkhead box protein I1 (FoxI1),GO:0008301; GO:0003705; GO:0009653; GO:0030154; GO:0048264; GO:0003690; GO:0007398; GO:0009790; GO:0000122; GO:0007399; GO:0005634; GO:0048513; GO:0045893; GO:0051090; GO:0043565; GO:0008134; GO:0005667,"DNA binding, bending; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; anatomical structure morphogenesis; cell differentiation; determination of ventral identity; double-stranded DNA binding; ectoderm development; embryo development; negative regulation of transcription from RNA polymerase II promoter; nervous system development; nucleus; organ development; positive regulation of transcription, DNA-dependent; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; transcription factor binding; transcription factor complex",PF00250;,,,,,,,,,FOXI1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; determination of ventral identity [GO:0048264]; ectoderm development [GO:0007398]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp142829_c0_seq2,1114,47.5763,1.00308524,0,12,,1.00E-23,Q64731,Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6),Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6),GO:0003677; GO:0061146; GO:0007507; GO:0005634; GO:0030166; GO:0030111; GO:0043565; GO:0003700; GO:0006351; GO:0007495,"DNA binding; Peyer's patch morphogenesis; heart development; nucleus; proteoglycan biosynthetic process; regulation of Wnt receptor signaling pathway; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; visceral mesoderm-endoderm interaction involved in midgut development",PF00250;,2.00E-14,CHOYP_LOC100313609.1.1,,,,,,,FOXL1_MOUSE,Mus musculus (Mouse),"heart development [GO:0007507]; Peyer's patch morphogenesis [GO:0061146]; proteoglycan biosynthetic process [GO:0030166]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; transcription, DNA-templated [GO:0006351]; visceral mesoderm-endoderm interaction involved in midgut development [GO:0007495]" comp142830_c0_seq1,2687,42.687,0.52308858,16,3,,5.00E-62,B8JK76,Serologically defined colon cancer antigen 8 homolog,Serologically defined colon cancer antigen 8 homolog,GO:0030054; GO:0005814,cell junction; centriole,PF15964;,,,,,,,,,SDCG8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),centrosome organization [GO:0051297] comp142830_c0_seq3,2698,42.6983,0.53749556,8,9,,5.00E-62,B8JK76,Serologically defined colon cancer antigen 8 homolog,Serologically defined colon cancer antigen 8 homolog,GO:0030054; GO:0005814,cell junction; centriole,PF15964;,,,,,,,,,SDCG8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),centrosome organization [GO:0051297] comp142831_c1_seq17,590,30.5085,0.14637813,0,0,,,,,,,,,,,1.00E-17,ruditapes_c1304,,,,,,, comp142832_c0_seq1,1272,42.2956,0.6025452,45,143,,0,Q9UPP1,Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8),Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8),GO:0000082; GO:0007420; GO:0003682; GO:0071558; GO:0051864; GO:0032454; GO:0035575; GO:0005506; GO:0035064; GO:0061188; GO:0005730; GO:0045943; GO:0006351; GO:0008270,"G1/S transition of mitotic cell cycle; brain development; chromatin binding; histone demethylase activity (H3-K27 specific); histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific); histone demethylase activity (H4-K20 specific); iron ion binding; methylated histone residue binding; negative regulation of chromatin silencing at rDNA; nucleolus; positive regulation of transcription from RNA polymerase I promoter; transcription, DNA-dependent; zinc ion binding",PF02373;PF00628;,1.00E-167,CHOYP_BRAFLDRAFT_119367.1.1,,,,,,,PHF8_HUMAN,Homo sapiens (Human),"brain development [GO:0007420]; G1/S transition of mitotic cell cycle [GO:0000082]; histone H3-K27 demethylation [GO:0071557]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; histone H4-K20 demethylation [GO:0035574]; negative regulation of chromatin silencing at rDNA [GO:0061188]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; transcription, DNA-templated [GO:0006351]" comp142832_c0_seq5,341,43.4018,0.5071406,0,0,,7.00E-13,Q80TJ7,Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8),Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8),GO:0000082; GO:0007420; GO:0003682; GO:0071558; GO:0051864; GO:0032454; GO:0035575; GO:0005506; GO:0035064; GO:0061188; GO:0005730; GO:0045943; GO:0006351; GO:0008270,"G1/S transition of mitotic cell cycle; brain development; chromatin binding; histone demethylase activity (H3-K27 specific); histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific); histone demethylase activity (H4-K20 specific); iron ion binding; methylated histone residue binding; negative regulation of chromatin silencing at rDNA; nucleolus; positive regulation of transcription from RNA polymerase I promoter; transcription, DNA-dependent; zinc ion binding",PF02373;PF00628;,,,,,,,,,PHF8_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; G1/S transition of mitotic cell cycle [GO:0000082]; histone H3-K27 demethylation [GO:0071557]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; histone H4-K20 demethylation [GO:0035574]; negative regulation of chromatin silencing at rDNA [GO:0061188]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; transcription, DNA-templated [GO:0006351]" comp142832_c1_seq3,1228,42.8339,0.4803008,10,5,,5.00E-13,Q9WTU0,Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2),Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2),GO:0051213; GO:0032454; GO:0005506; GO:0035064; GO:0061188; GO:0005730; GO:0003713; GO:0006351; GO:0008270,"dioxygenase activity; histone demethylase activity (H3-K9 specific); iron ion binding; methylated histone residue binding; negative regulation of chromatin silencing at rDNA; nucleolus; transcription coactivator activity; transcription, DNA-dependent; zinc ion binding",PF02373;PF00628;,,,,,,,,,PHF2_MOUSE,Mus musculus (Mouse),"histone H3-K9 demethylation [GO:0033169]; negative regulation of chromatin silencing at rDNA [GO:0061188]; protein demethylation [GO:0006482]; transcription, DNA-templated [GO:0006351]" comp142834_c2_seq1,221,33.9367,0.1581229,18,79,,,,,,,,,,,3.00E-12,ruditapes_c19336,,,,,,, comp142834_c3_seq10,260,46.1538,0.37286266,0,0,,,,,,,,,1.00E-38,CHOYP_LOC100123553.1.1,,,,,,,,, comp142834_c3_seq9,290,42.069,0.24406217,23,19,,1.00E-27,Q9Y4A5,Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog),GO:0035267; GO:0000125; GO:0030914; GO:0043968; GO:0043967; GO:0016578; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0003712; GO:0033276; GO:0006351,"NuA4 histone acetyltransferase complex; PCAF complex; STAGA complex; histone H2A acetylation; histone H4 acetylation; histone deubiquitination; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription cofactor activity; transcription factor TFTC complex; transcription, DNA-dependent",PF02259;PF00454;,,,,,,,,,TRRAP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142835_c0_seq4,625,42.56,0.32260733,47,60,,,,,,,,,2.00E-29,CHOYP_LOC100497254.1.1,,,,,,,,, comp142836_c0_seq3,1014,44.8718,1.11827463,64,289,,,,,,,,,,,5.00E-43,ruditapes2_c120,,,,,,, comp142837_c1_seq1,5738,43.7609,0.45137763,988,1067,,0,P12270,Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein),Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein),GO:0005524; GO:0000189; GO:0006404; GO:0005975; GO:0051301; GO:0035457; GO:0003682; GO:0019221; GO:0005868; GO:0070840; GO:0019898; GO:0015758; GO:0031072; GO:0000776; GO:0003729; GO:0031990; GO:0051019; GO:0007067; GO:0007077; GO:0072686; GO:0007094; GO:0046832; GO:0000122; GO:0045947; GO:0042405; GO:0031965; GO:0034399; GO:0044615; GO:0006999; GO:0005487; GO:0005654; GO:0031453; GO:0090267; GO:0046827; GO:0042307; GO:0042803; GO:0010827; GO:0010965; GO:1901673; GO:0070849; GO:0004828; GO:0006434; GO:0044281; GO:0055085; GO:0015631; GO:0016032,ATP binding; MAPK import into nucleus; RNA import into nucleus; carbohydrate metabolic process; cell division; cellular response to interferon-alpha; chromatin binding; cytokine-mediated signaling pathway; cytoplasmic dynein complex; dynein complex binding; extrinsic to membrane; glucose transport; heat shock protein binding; kinetochore; mRNA binding; mRNA export from nucleus in response to heat stress; mitogen-activated protein kinase binding; mitosis; mitotic nuclear envelope disassembly; mitotic spindle; mitotic spindle assembly checkpoint; negative regulation of RNA export from nucleus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of translational initiation; nuclear inclusion body; nuclear membrane; nuclear periphery; nuclear pore nuclear basket; nuclear pore organization; nucleocytoplasmic transporter activity; nucleoplasm; positive regulation of heterochromatin assembly; positive regulation of mitotic cell cycle spindle assembly checkpoint; positive regulation of protein export from nucleus; positive regulation of protein import into nucleus; protein homodimerization activity; regulation of glucose transport; regulation of mitotic sister chromatid separation; regulation of spindle assembly involved in mitosis; response to epidermal growth factor stimulus; serine-tRNA ligase activity; seryl-tRNA aminoacylation; small molecule metabolic process; transmembrane transport; tubulin binding; viral process,PF07926;,,,,,,,,,TPR_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp142837_c1_seq2,2787,45.6405,0.50962846,11,24,,,,,,,,,1.00E-32,CHOYP_TPR.2.2,,,,,,,,, comp142838_c3_seq1,1782,34.624,0.69757455,115,830,,3.00E-29,Q9FRL8,Glutathione S-transferase DHAR2 (EC 2.5.1.18) (Chloride intracellular channel homolog 2) (CLIC homolog 2) (Glutathione-dependent dehydroascorbate reductase 2) (AtDHAR2) (CytDHAR) (GSH-dependent dehydroascorbate reductase 2),Glutathione S-transferase DHAR2 (EC 2.5.1.18) (Chloride intracellular channel homolog 2) (CLIC homolog 2) (Glutathione-dependent dehydroascorbate reductase 2) (AtDHAR2) (CytDHAR) (GSH-dependent dehydroascorbate reductase 2),GO:0005829; GO:0043295; GO:0045174; GO:0004364; GO:0005886; GO:0010731; GO:0006950; GO:0009636,cytosol; glutathione binding; glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; plasma membrane; protein glutathionylation; response to stress; response to toxic substance,PF13417;,,,,,,,,,DHAR2_ARATH,Arabidopsis thaliana (Mouse-ear cress),glutathione metabolic process [GO:0006749]; protein glutathionylation [GO:0010731] comp142840_c6_seq1,1034,41.3926,0.85972931,14,179,,8.00E-17,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp142841_c2_seq1,2072,37.5,0.54807822,2,0,,1.00E-37,Q15527,Surfeit locus protein 2 (Surf-2),Surfeit locus protein 2 (Surf-2),,,PF05477;,,,,,,,,,SURF2_HUMAN,Homo sapiens (Human), comp142841_c2_seq3,1758,37.9408,0.57236775,1,0,,3.00E-36,P09926,Surfeit locus protein 2 (Surf-2),Surfeit locus protein 2 (Surf-2),,,PF05477;,2.00E-22,CHOYP_BRAFLDRAFT_196630.1.1,,,,,,,SURF2_MOUSE,Mus musculus (Mouse), comp142841_c2_seq7,1795,38.0501,0.58643105,0,0,,5.00E-40,Q15527,Surfeit locus protein 2 (Surf-2),Surfeit locus protein 2 (Surf-2),,,PF05477;,2.00E-22,CHOYP_BRAFLDRAFT_196630.1.1,9.00E-43,ruditapes_c7912,,,,,SURF2_HUMAN,Homo sapiens (Human), comp142842_c1_seq3,2058,41.8853,0.37857461,24,128,,,,,,,,,,,3.00E-25,ruditapes_c22793,,,,,,, comp142843_c0_seq5,2449,34.3814,0.50216074,24,44,,7.00E-14,Q6L0S6,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,1.00E-11,ruditapes_lrc13143,,,,,DNAJ_PICTO,Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp142844_c0_seq1,2513,44.9662,0.47610037,388,1100,,9.00E-29,Q99MR1,PERQ amino acid-rich with GYF domain-containing protein 1 (GRB10-interacting GYF protein 1),PERQ amino acid-rich with GYF domain-containing protein 1 (GRB10-interacting GYF protein 1),GO:0048009,insulin-like growth factor receptor signaling pathway,PF02213;,6.00E-24,CHOYP_PERQ2.2.2,4.00E-56,ruditapes_c7093,,,,,PERQ1_MOUSE,Mus musculus (Mouse),insulin-like growth factor receptor signaling pathway [GO:0048009] comp142844_c0_seq2,2348,40.8007,0.49823035,231,830,,3.00E-23,Q7KQM6,PERQ amino acid-rich with GYF domain-containing protein CG11148,PERQ amino acid-rich with GYF domain-containing protein CG11148,GO:0005813; GO:0072686,centrosome; mitotic spindle,PF02213;,3.00E-14,CHOYP_PERQ2.2.2,,,,,,,PERQ1_DROME,Drosophila melanogaster (Fruit fly),muscle cell cellular homeostasis [GO:0046716]; neuron cellular homeostasis [GO:0070050]; regulation of autophagy [GO:0010506] comp142845_c0_seq1,1941,39.3096,0.37585721,326,924,,0,P23128,Putative ATP-dependent RNA helicase me31b (EC 3.6.4.13) (Maternal expression at 31B),Putative ATP-dependent RNA helicase me31b (EC 3.6.4.13) (Maternal expression at 31B),GO:0005524; GO:0004004; GO:0043186; GO:0003723; GO:0000932; GO:0033962; GO:0035195; GO:0005875; GO:0007095,ATP binding; ATP-dependent RNA helicase activity; P granule; RNA binding; cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; gene silencing by miRNA; microtubule associated complex; mitotic G2 DNA damage checkpoint,PF00270;PF00271;,0,CHOYP_LOC100161360.1.1,,,,,,,DDX6_DROME,Drosophila melanogaster (Fruit fly),cytoplasmic mRNA processing body assembly [GO:0033962]; gene silencing by miRNA [GO:0035195]; habituation [GO:0046959]; mitotic G2 DNA damage checkpoint [GO:0007095]; ovarian follicle cell development [GO:0030707]; pole cell formation [GO:0007279]; regulation of defense response to virus [GO:0050688]; regulation of glucose metabolic process [GO:0010906]; regulation of olfactory learning [GO:0090328]; RNA secondary structure unwinding [GO:0010501] comp142846_c1_seq1,406,50,0.41950368,7,37,,4.00E-49,Q3LXA3,Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)],Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)],GO:0005524; GO:0034012; GO:0005829; GO:0006071; GO:0004371; GO:0045087; GO:0046872; GO:0050354,ATP binding; FAD-AMP lyase (cyclizing) activity; cytosol; glycerol metabolic process; glycerone kinase activity; innate immune response; metal ion binding; triokinase activity,PF02733;PF02734;,2.00E-15,CHOYP_BRAFLDRAFT_115040.1.1,,,,,,,DHAK_HUMAN,Homo sapiens (Human),carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol metabolic process [GO:0006071]; innate immune response [GO:0045087]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088] comp142846_c2_seq1,5710,40.9457,0.59385034,7,0,,0,O70472,Transmembrane protein 131 (Protein RW1),Transmembrane protein 131 (Protein RW1),GO:0016021,integral to membrane,PF12371;,3.00E-159,CHOYP_BRAFLDRAFT_73285.2.2,,,,,,,TM131_MOUSE,Mus musculus (Mouse), comp142846_c2_seq2,5827,41.1361,0.59283765,0,0,,0,O70472,Transmembrane protein 131 (Protein RW1),Transmembrane protein 131 (Protein RW1),GO:0016021,integral to membrane,PF12371;,3.00E-159,CHOYP_BRAFLDRAFT_73285.2.2,,,,,,,TM131_MOUSE,Mus musculus (Mouse), comp142846_c2_seq4,4421,41.1219,0.61583869,0,0,,7.00E-47,A2VDJ0,Transmembrane protein 131-like,Transmembrane protein 131-like,GO:0016021,integral to membrane,PF12371;,,,,,,,,,T131L_HUMAN,Homo sapiens (Human),negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; Wnt signaling pathway [GO:0016055] comp142846_c2_seq5,1758,37.9408,0.5377272,0,0,,3.00E-63,Q9V7H4,Transmembrane protein 131 homolog,Transmembrane protein 131 homolog,GO:0016021,integral to membrane,PF12371;,6.00E-155,CHOYP_BRAFLDRAFT_73285.2.2,,,,,,,TM131_DROME,Drosophila melanogaster (Fruit fly), comp142846_c2_seq6,4304,40.869,0.61810248,0,0,,1.00E-160,O70472,Transmembrane protein 131 (Protein RW1),Transmembrane protein 131 (Protein RW1),GO:0016021,integral to membrane,PF12371;,,,,,,,,,TM131_MOUSE,Mus musculus (Mouse), comp142846_c3_seq1,1169,42.2583,0.17424268,10,165,,7.00E-56,Q3LXA3,Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)],Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)],GO:0005524; GO:0034012; GO:0005829; GO:0006071; GO:0004371; GO:0045087; GO:0046872; GO:0050354,ATP binding; FAD-AMP lyase (cyclizing) activity; cytosol; glycerol metabolic process; glycerone kinase activity; innate immune response; metal ion binding; triokinase activity,PF02733;PF02734;,3.00E-18,CHOYP_BRAFLDRAFT_115040.1.1,,,,,,,DHAK_HUMAN,Homo sapiens (Human),carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol metabolic process [GO:0006071]; innate immune response [GO:0045087]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088] comp142847_c0_seq2,1129,39.7697,0.42711102,10,30,,,,,,,,,,,1.00E-12,ruditapes_c31907,,,,,,, comp142847_c0_seq3,1501,44.7035,0.28304541,123,356,,5.00E-177,Q91857,Transcription initiation factor TFIID subunit 6 (xTAF6) (Transcription initiation factor TFIID 60 kDa subunit) (TAF(II)60) (TAFII-60) (TAFII60) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70),Transcription initiation factor TFIID subunit 6 (xTAF6) (Transcription initiation factor TFIID 60 kDa subunit) (TAF(II)60) (TAFII-60) (TAFII60) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70),GO:0006352; GO:0071339; GO:0051090,"DNA-dependent transcription, initiation; MLL1 complex; regulation of sequence-specific DNA binding transcription factor activity",PF02969;PF07571;,4.00E-137,CHOYP_AAEL_AAEL006988.1.1,,,,,,,TAF6_XENLA,Xenopus laevis (African clawed frog),"DNA-templated transcription, initiation [GO:0006352]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]" comp142849_c0_seq1,1832,35.8624,0.47765487,204,815,,1.00E-88,Q7TPN3,GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V),GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V),GO:0006506; GO:0005789; GO:0016021; GO:0097502; GO:0000030,GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; mannosylation; mannosyltransferase activity,PF04188;,,,,,,,,,PIGV_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp142850_c0_seq1,3283,38.6537,0.32980169,4570,26494,,0,Q6EE31,T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta),T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta),GO:0005524; GO:0005737; GO:0005815; GO:0006457,ATP binding; cytoplasm; microtubule organizing center; protein folding,PF00118;,0,CHOYP_TCPQ.1.1,,,,,,,TCPQ_CHICK,Gallus gallus (Chicken),protein folding [GO:0006457] comp142852_c0_seq1,710,38.4507,0.46745655,15,139,,5.00E-65,Q5HZL1,ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1),ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1),GO:0004527; GO:0003676; GO:0090305; GO:0008270,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; zinc ion binding,PF00929;PF06839;,2.00E-61,CHOYP_ERI2.1.1,,,,,,,ERI2_XENLA,Xenopus laevis (African clawed frog), comp142852_c0_seq2,2210,39.7738,0.41230778,29,148,,3.00E-99,Q5HZL1,ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1),ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1),GO:0004527; GO:0003676; GO:0090305; GO:0008270,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; zinc ion binding,PF00929;PF06839;,,,,,,,,,ERI2_XENLA,Xenopus laevis (African clawed frog), comp142852_c0_seq3,2166,39.7507,0.35085928,16,113,,1.00E-33,Q7TMF2,3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1),3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1),GO:0008408; GO:0005737; GO:0031047; GO:0071204; GO:0071207; GO:0046872; GO:0005730; GO:0031125; GO:0019843; GO:0043022,3'-5' exonuclease activity; cytoplasm; gene silencing by RNA; histone pre-mRNA 3'end processing complex; histone pre-mRNA stem-loop binding; metal ion binding; nucleolus; rRNA 3'-end processing; rRNA binding; ribosome binding,PF00929;PF02037;,2.00E-80,CHOYP_ERI2.1.1,,,,,,,ERI1_MOUSE,Mus musculus (Mouse),"exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; gene silencing by RNA [GO:0031047]; rRNA 3'-end processing [GO:0031125]" comp142856_c0_seq4,1822,32.4918,0.56974702,55,102,,1.00E-13,Q3ZCK8,Cytochrome c oxidase assembly factor 5,Cytochrome c oxidase assembly factor 5,GO:0005739,mitochondrion,PF10203;,,,,,,,,,COA5_BOVIN,Bos taurus (Bovine), comp142856_c0_seq9,1300,33,0.49061697,0,0,,6.00E-14,Q3ZCK8,Cytochrome c oxidase assembly factor 5,Cytochrome c oxidase assembly factor 5,GO:0005739,mitochondrion,PF10203;,,,,,,,,,COA5_BOVIN,Bos taurus (Bovine), comp142857_c0_seq1,804,39.4279,0.7471763,526,2768,,2.00E-29,A0JN61,DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9),DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9),GO:0009360; GO:0003899; GO:0001669; GO:0001635; GO:0051607; GO:0045087; GO:0007218; GO:0000166; GO:0005634; GO:0005886; GO:0006383,DNA polymerase III complex; DNA-directed RNA polymerase activity; acrosomal vesicle; calcitonin gene-related polypeptide receptor activity; defense response to virus; innate immune response; neuropeptide signaling pathway; nucleotide binding; nucleus; plasma membrane; transcription from RNA polymerase III promoter,PF03874;,,,,,,,,,RPC9_BOVIN,Bos taurus (Bovine),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; neuropeptide signaling pathway [GO:0007218]; transcription from RNA polymerase III promoter [GO:0006383]; transcription initiation from RNA polymerase III promoter [GO:0006384] comp142857_c0_seq2,2988,35.5756,0.68776867,184,1965,,,,,,,,,,,2.00E-135,ruditapes_c1225,,,,,,, comp142857_c0_seq3,3936,34.3242,0.67305345,3220,11362,,0,Q5R501,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) (EC 2.4.99.18),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) (EC 2.4.99.18),GO:0004579; GO:0016021; GO:0008250; GO:0018279; GO:0006486,dolichyl-diphosphooligosaccharide-protein glycotransferase activity; integral to membrane; oligosaccharyltransferase complex; protein N-linked glycosylation via asparagine; protein glycosylation,PF03345;,0,CHOYP_OST48.1.1,1.00E-128,ruditapes_c13402,,,,,OST48_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] comp142857_c0_seq4,879,37.9977,0.44334146,159,1054,,2.00E-111,Q9UK41,Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28),Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28),GO:0000813; GO:0005829; GO:0016197; GO:0031902; GO:0031397; GO:0005886; GO:0015031; GO:0043162; GO:0019082; GO:0019068,ESCRT I complex; cytosol; endosomal transport; late endosome membrane; negative regulation of protein ubiquitination; plasma membrane; protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; viral protein processing; virion assembly,PF03997;,9.00E-86,CHOYP_LOC101164168.1.1,1.00E-63,ruditapes_c15640,,,,,VPS28_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; endosomal transport [GO:0016197]; intracellular transport of virus [GO:0075733]; multivesicular body assembly [GO:0036258]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058] comp142858_c0_seq1,1780,43.8202,0.34232985,107,547,,0,O95985,DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta-1),DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta-1),GO:0005524; GO:0003677; GO:0003916; GO:0003917; GO:0006265; GO:0007059; GO:0000793; GO:0005634,ATP binding; DNA binding; DNA topoisomerase activity; DNA topoisomerase type I activity; DNA topological change; chromosome segregation; condensed chromosome; nucleus,PF01131;PF01751;,0,CHOYP_TOP3B.1.1,,,,,,,TOP3B_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; DNA topological change [GO:0006265] comp142859_c0_seq1,1553,39.472,0.45539222,7,115,,3.00E-37,Q01976,ADP-ribose pyrophosphatase (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase),ADP-ribose pyrophosphatase (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase),GO:0047631; GO:0046872; GO:0005739; GO:0019693,ADP-ribose diphosphatase activity; metal ion binding; mitochondrion; ribose phosphate metabolic process,PF00293;,,,,,,,,,ADPP_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ribose phosphate metabolic process [GO:0019693] comp142859_c0_seq4,1542,39.4293,0.47749799,0,0,,5.00E-61,Q9UKK9,ADP-sugar pyrophosphatase (EC 3.6.1.13) (8-oxo-dGDP phosphatase) (EC 3.6.1.58) (Nucleoside diphosphate-linked moiety X motif 5) (Nudix motif 5) (YSA1H),ADP-sugar pyrophosphatase (EC 3.6.1.13) (8-oxo-dGDP phosphatase) (EC 3.6.1.58) (Nuclear ATP-synthesis protein NUDIX5) (EC 2.7.7.-) (Nucleoside diphosphate-linked moiety X motif 5) (Nudix motif 5) (hNUDT5) (YSA1H),GO:0047631; GO:0019144; GO:0019303; GO:0005829; GO:0000287; GO:0034656; GO:0017110; GO:0009117; GO:0009191; GO:0030515,ADP-ribose diphosphatase activity; ADP-sugar diphosphatase activity; D-ribose catabolic process; cytosol; magnesium ion binding; nucleobase-containing small molecule catabolic process; nucleoside-diphosphatase activity; nucleotide metabolic process; ribonucleoside diphosphate catabolic process; snoRNA binding,PF00293;,4.00E-30,CHOYP_LOC100691676.1.1,,,,,,,NUDT5_HUMAN,Homo sapiens (Human),D-ribose catabolic process [GO:0019303]; nucleobase-containing small molecule catabolic process [GO:0034656]; nucleotide metabolic process [GO:0009117]; ribonucleoside diphosphate catabolic process [GO:0009191] comp142860_c0_seq1,2187,41.5638,0.37858422,347,2741,,0,Q7SXM7,U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31),U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31),GO:0071339; GO:0003723; GO:0046540; GO:0000244; GO:0000398; GO:0060041; GO:0005681,"MLL1 complex; RNA binding; U4/U6 x U5 tri-snRNP complex; assembly of spliceosomal tri-snRNP; mRNA splicing, via spliceosome; retina development in camera-type eye; spliceosomal complex",PF01798;PF09785;,4.00E-139,CHOYP_PRP31.6.6,,,,,,,PRP31_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA splicing, via spliceosome [GO:0000398]; retina development in camera-type eye [GO:0060041]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp142860_c0_seq2,257,42.8016,0.25621043,0,23,,5.00E-30,Q7SXM7,U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31),U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31),GO:0071339; GO:0003723; GO:0046540; GO:0000244; GO:0000398; GO:0060041; GO:0005681,"MLL1 complex; RNA binding; U4/U6 x U5 tri-snRNP complex; assembly of spliceosomal tri-snRNP; mRNA splicing, via spliceosome; retina development in camera-type eye; spliceosomal complex",PF01798;PF09785;,,,,,,,,,PRP31_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"mRNA splicing, via spliceosome [GO:0000398]; retina development in camera-type eye [GO:0060041]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp142862_c0_seq4,1260,26.6667,0.53735829,0,8,,,,,,,,,,,3.00E-16,ruditapes_c14826,,,,,,, comp142863_c0_seq2,2422,39.4715,0.39612546,63,228,,,,,,,,,2.00E-36,CHOYP_LOC100891594.2.2,,,,,,,,, comp142863_c0_seq3,1839,41.2181,0.36653127,19,113,,1.00E-18,Q1MTN8,UPF0661 TPR repeat-containing protein C16D10.01c,Probable assembly chaperone of rpl4,GO:0005730; GO:0043234,nucleolus; protein complex,PF13181;,2.00E-35,CHOYP_LOC100891594.1.2,,,,,,,YGC1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ribosome biogenesis [GO:0042254] comp142866_c0_seq2,1547,29.735,0.36100761,179,1215,,,,,,,,,,,3.00E-17,ruditapes_c11951,,,,,,, comp142866_c1_seq1,2108,36.2429,0.48459139,384,1000,,3.00E-56,Q5RB75,NudC domain-containing protein 3,NudC domain-containing protein 3,,,PF04969;PF14050;,,,3.00E-87,ruditapes_c19176,,,,,NUDC3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp142866_c1_seq2,1363,36.4637,0.64909782,52,150,,2.00E-18,Q54M64,Nuclear movement protein nudC (Nuclear distribution protein C homolog),Nuclear movement protein nudC (Nuclear distribution protein C homolog),GO:0051301; GO:0005829; GO:0000741; GO:0005874; GO:0007067; GO:0005634,cell division; cytosol; karyogamy; microtubule; mitosis; nucleus,PF04969;,7.00E-52,CHOYP_LOC100567407.1.1,,,,,,,NUDC_DICDI,Dictyostelium discoideum (Slime mold),cell division [GO:0051301]; karyogamy [GO:0000741]; mitotic nuclear division [GO:0007067] comp142868_c0_seq1,909,32.3432,0.29490776,20,193,,,,,,,,,,,3.00E-58,ruditapes2_c1060,,,,,,, comp142868_c0_seq3,620,31.7742,0.32142941,3,21,,,,,,,,,,,2.00E-70,ruditapes_c4838,,,,,,, comp142870_c0_seq1,1968,41.1077,0.97018995,300,694,,2.00E-146,O97578,Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] (Fragment),Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] (Fragment),GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08773;PF00112;,2.00E-17,CHOYP_BRAFLDRAFT_125840.1.1,3.00E-18,ruditapes_c7740,,,,,CATC_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),proteolysis involved in cellular protein catabolic process [GO:0051603] comp142871_c0_seq1,1503,35.7951,0.3533592,1145,4851,,8.00E-22,P70097,"Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)","Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)",GO:0009055; GO:0020037; GO:0016021; GO:0046872; GO:0005749; GO:0000104; GO:0006099,electron carrier activity; heme binding; integral to membrane; metal ion binding; mitochondrial respiratory chain complex II; succinate dehydrogenase activity; tricarboxylic acid cycle,PF01127;,,,,,,,,,C560_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),tricarboxylic acid cycle [GO:0006099] comp142875_c0_seq2,355,31.2676,0.346756,50,172,,,,,,,,,,,4.00E-14,ruditapes_c12534,,,,,,, comp142876_c0_seq1,1973,36.8474,0.3736486,224,615,,1.00E-98,P51688,N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase),GO:0016250; GO:0005975; GO:0003824; GO:0006027; GO:0043202; GO:0046872; GO:0006029; GO:0044281; GO:0008484,N-sulfoglucosamine sulfohydrolase activity; carbohydrate metabolic process; catalytic activity; glycosaminoglycan catabolic process; lysosomal lumen; metal ion binding; proteoglycan metabolic process; small molecule metabolic process; sulfuric ester hydrolase activity,PF16347;PF00884;,,,,,,,,,SPHM_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] comp142876_c1_seq2,557,45.2424,0.35167442,3,36,,,,,,,,,5.00E-68,CHOYP_LOC100378056.1.1,,,,,,,,, comp142880_c0_seq1,1110,42.0721,0.47306392,50,125,,8.00E-52,C0IN03,Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1) (piRNA methyltransferase 1),Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1) (piRNA methyltransferase 1),GO:0008171; GO:0043186; GO:0003723; GO:0008173; GO:0031047; GO:0046872; GO:0034587,O-methyltransferase activity; P granule; RNA binding; RNA methyltransferase activity; gene silencing by RNA; metal ion binding; piRNA metabolic process,,9.00E-24,CHOYP_BRAFLDRAFT_68822.1.1,,,,,,,HENMT_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),gene silencing by RNA [GO:0031047]; oocyte development [GO:0048599]; piRNA metabolic process [GO:0034587]; RNA methylation [GO:0001510] comp142880_c0_seq2,1134,41.4462,0.49890149,19,151,,3.00E-31,Q230X8,Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1),Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1),GO:0008171; GO:0003723; GO:0008173; GO:0031047; GO:0031039; GO:0046872; GO:0034587; GO:0031049,O-methyltransferase activity; RNA binding; RNA methyltransferase activity; gene silencing by RNA; macronucleus; metal ion binding; piRNA metabolic process; programmed DNA elimination,,,,,,,,,,HENMT_TETTS,Tetrahymena thermophila (strain SB210),gene silencing by RNA [GO:0031047]; piRNA metabolic process [GO:0034587]; programmed DNA elimination [GO:0031049]; RNA methylation [GO:0001510] comp142881_c4_seq3,2231,38.3684,0.33145787,277,1682,,8.00E-46,Q5ZIJ0,BUD13 homolog,BUD13 homolog,,,PF09736;,2.00E-22,CHOYP_LOC587806.1.1,,,,,,,BUD13_CHICK,Gallus gallus (Chicken), comp142882_c0_seq1,3996,35.3353,0.26773233,92,9,,8.00E-15,Q03410,Synaptonemal complex protein 1 (SCP-1),Synaptonemal complex protein 1 (SCP-1),GO:0003677; GO:0051301; GO:0005634; GO:0000795; GO:0007130,DNA binding; cell division; nucleus; synaptonemal complex; synaptonemal complex assembly,PF05483;,2.00E-12,CHOYP_USO1.8.11,,,,,,,SYCP1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130] comp142882_c0_seq4,2450,36.0408,0.27245447,5,0,,6.00E-15,Q03410,Synaptonemal complex protein 1 (SCP-1),Synaptonemal complex protein 1 (SCP-1),GO:0003677; GO:0051301; GO:0005634; GO:0000795; GO:0007130,DNA binding; cell division; nucleus; synaptonemal complex; synaptonemal complex assembly,PF05483;,1.00E-12,CHOYP_USO1.8.11,,,,,,,SYCP1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130] comp142882_c0_seq6,4013,35.3102,0.2669959,57,17,,1.00E-14,Q03410,Synaptonemal complex protein 1 (SCP-1),Synaptonemal complex protein 1 (SCP-1),GO:0003677; GO:0051301; GO:0005634; GO:0000795; GO:0007130,DNA binding; cell division; nucleus; synaptonemal complex; synaptonemal complex assembly,PF05483;,2.00E-12,CHOYP_USO1.8.11,,,,,,,SYCP1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130] comp142883_c0_seq1,3346,34.5487,0.53260979,31,300,,4.00E-11,P40464,Mitochondrial FAD carrier protein FLX1,Mitochondrial FAD carrier protein FLX1,GO:0015230; GO:0016021; GO:0005743; GO:0005739,FAD transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; mitochondrion,PF00153;,8.00E-24,CHOYP_S2538.1.2,,,,,,,FLX1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),FAD transport [GO:0015883]; translation [GO:0006412] comp142883_c0_seq2,3278,34.4417,0.53664437,16,156,,3.00E-93,Q96DW6,Solute carrier family 25 member 38,Solute carrier family 25 member 38,GO:0030218; GO:0006783; GO:0016021; GO:0005743; GO:0006810,erythrocyte differentiation; heme biosynthetic process; integral to membrane; mitochondrial inner membrane; transport,PF00153;,2.00E-24,CHOYP_S2538.1.2,4.00E-51,ruditapes2_c973,,,,,S2538_HUMAN,Homo sapiens (Human),erythrocyte differentiation [GO:0030218]; heme biosynthetic process [GO:0006783]; translation [GO:0006412] comp142884_c0_seq1,3263,44.5602,0.43705467,426,967,,0,Q9UNS1,Protein timeless homolog (hTIM),Protein timeless homolog (hTIM),GO:0048754; GO:0051301; GO:0007623; GO:0009582; GO:0009790; GO:0030324; GO:0007067; GO:0002009; GO:0000122; GO:0045892; GO:0000790; GO:0006974; GO:0006351,"branching morphogenesis of an epithelial tube; cell division; circadian rhythm; detection of abiotic stimulus; embryo development; lung development; mitosis; morphogenesis of an epithelium; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nuclear chromatin; response to DNA damage stimulus; transcription, DNA-dependent",PF04821;PF05029;,0,CHOYP_LOC579123.1.1,,,,,,,TIM_HUMAN,Homo sapiens (Human),"branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA replication [GO:0006260]; lung development [GO:0030324]; mitotic nuclear division [GO:0007067]; morphogenesis of an epithelium [GO:0002009]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of circadian rhythm [GO:0042752]; response to abiotic stimulus [GO:0009628]; transcription, DNA-templated [GO:0006351]" comp142885_c0_seq1,3317,43.6841,0.46154466,553,1618,,0,Q10567,AP-1 complex subunit beta-1 (Adapter-related protein complex 1 subunit beta-1) (Adaptor protein complex AP-1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit),AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit),GO:0000139; GO:0019886; GO:0030131; GO:0030665; GO:0030659; GO:0005829; GO:0006897; GO:0006886; GO:0005765; GO:0006892; GO:0008565; GO:0050690; GO:0032588; GO:0005215; GO:0016032,Golgi membrane; antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin adaptor complex; clathrin-coated vesicle membrane; cytoplasmic vesicle membrane; cytosol; endocytosis; intracellular protein transport; lysosomal membrane; post-Golgi vesicle-mediated transport; protein transporter activity; regulation of defense response to virus by virus; trans-Golgi network membrane; transporter activity; viral process,PF01602;PF02883;PF09066;,0,CHOYP_ISCW_ISCW011108.1.1,,,,,,,AP1B1_HUMAN,Homo sapiens (Human),antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; regulation of defense response to virus by virus [GO:0050690]; vesicle-mediated transport [GO:0016192] comp142885_c0_seq2,1490,38.9262,0.46202824,10,153,,,,,,,,,2.00E-108,CHOYP_ISCW_ISCW011108.1.1,,,,,,,,, comp142886_c0_seq1,2046,36.5591,0.44226957,179,1759,,3.00E-128,Q5PPJ4,Deoxyhypusine hydroxylase (DOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase),Deoxyhypusine hydroxylase (DOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase),GO:0019135; GO:0046872; GO:0008612,deoxyhypusine monooxygenase activity; metal ion binding; peptidyl-lysine modification to hypusine,,2.00E-66,CHOYP_LOC100378204.1.1,,,,,,,DOHH_RAT,Rattus norvegicus (Rat),peptidyl-lysine modification to peptidyl-hypusine [GO:0008612] comp142887_c0_seq1,2299,40.9743,0.57197126,14,33,,1.00E-144,Q99741,Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6),Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6),GO:0005524; GO:0006260; GO:0000076; GO:0051301; GO:0003682; GO:0005829; GO:0007067; GO:0008156; GO:0008285; GO:0005654; GO:0017111; GO:0000166; GO:0051984; GO:0032467; GO:0000079; GO:0030071; GO:0000083; GO:0051233; GO:0000922; GO:0007089,ATP binding; DNA replication; DNA replication checkpoint; cell division; chromatin binding; cytosol; mitosis; negative regulation of DNA replication; negative regulation of cell proliferation; nucleoplasm; nucleoside-triphosphatase activity; nucleotide binding; positive regulation of chromosome segregation; positive regulation of cytokinesis; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of mitotic metaphase/anaphase transition; regulation of transcription involved in G1/S transition of mitotic cell cycle; spindle midzone; spindle pole; traversing start control point of mitotic cell cycle,PF13401;PF09079;,,,,,,,,,CDC6_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication [GO:0006260]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; traversing start control point of mitotic cell cycle [GO:0007089] comp142887_c0_seq2,2285,40.919,0.56707378,13,39,,1.00E-58,P41411,Cell division control protein 18,Cell division control protein 18,GO:0005524; GO:0003689; GO:0006270; GO:0051301; GO:0007067; GO:0033314; GO:0005656; GO:0043596; GO:0006267,ATP binding; DNA clamp loader activity; DNA replication initiation; cell division; mitosis; mitotic DNA replication checkpoint; nuclear pre-replicative complex; nuclear replication fork; pre-replicative complex assembly involved in nuclear cell cycle DNA replication,PF00004;PF09079;,1.00E-94,CHOYP_BRAFLDRAFT_123390.1.1,,,,,,,CDC18_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell division [GO:0051301]; DNA replication initiation [GO:0006270]; mitotic DNA replication checkpoint [GO:0033314]; mitotic nuclear division [GO:0007067]; mitotic pre-replicative complex assembly [GO:1902985]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of DNA replication initiation [GO:1903468]; positive regulation of protein phosphorylation [GO:0001934] comp142887_c0_seq3,1241,43.2716,0.48610599,0,0,,4.00E-30,P09119,Cell division control protein 6,Cell division control protein 6,GO:0005524; GO:0016887; GO:0003688; GO:0031261; GO:0000082; GO:0005525; GO:0003924; GO:0051301; GO:0003682; GO:0005656; GO:0005886; GO:0006267; GO:0030174; GO:0031938,ATP binding; ATPase activity; DNA replication origin binding; DNA replication preinitiation complex; G1/S transition of mitotic cell cycle; GTP binding; GTPase activity; cell division; chromatin binding; nuclear pre-replicative complex; plasma membrane; pre-replicative complex assembly involved in nuclear cell cycle DNA replication; regulation of DNA-dependent DNA replication initiation; regulation of chromatin silencing at telomere,PF13401;PF09079;,5.00E-85,CHOYP_BRAFLDRAFT_123390.1.1,,,,,,,CDC6_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cell division [GO:0051301]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]; regulation of chromatin silencing at telomere [GO:0031938]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp142888_c1_seq2,1742,38.5189,0.60862228,5,13,,2.00E-82,B0CMA4,Insulin-induced gene 2 protein (INSIG-2),Insulin-induced gene 2 protein (INSIG-2),GO:0032933; GO:0032937; GO:0008203,SREBP signaling pathway; SREBP-SCAP-Insig complex; cholesterol metabolic process,PF07281;,1.00E-49,CHOYP_INSI2.1.1,,,,,,,INSI2_CALJA,Callithrix jacchus (White-tufted-ear marmoset),cholesterol biosynthetic process [GO:0006695]; cranial suture morphogenesis [GO:0060363]; inner ear morphogenesis [GO:0042472]; middle ear morphogenesis [GO:0042474]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of steroid biosynthetic process [GO:0010894]; palate development [GO:0060021]; SREBP signaling pathway [GO:0032933]; triglyceride metabolic process [GO:0006641] comp142890_c0_seq1,1245,38.6345,0.47466697,801,2190,,,,,,,,,1.00E-47,CHOYP_RU1C.2.2,,,,,,,,, comp142890_c0_seq2,1276,38.7147,0.5241429,900,2036,,6.00E-32,C3Z1P5,U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C),U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C),GO:0030619; GO:0005685; GO:0071004; GO:0000243; GO:0000395; GO:0003729; GO:0000387; GO:0008270,U1 snRNA binding; U1 snRNP; U2-type prespliceosome; commitment complex; mRNA 5'-splice site recognition; mRNA binding; spliceosomal snRNP assembly; zinc ion binding,PF06220;,1.00E-47,CHOYP_RU1C.1.2,8.00E-17,ruditapes_c3071,,,,,RU1C_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387] comp142890_c1_seq1,2521,40.1825,0.45622653,971,14017,,0,Q7QC84,"Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27)","Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27)",GO:0018478; GO:0004491; GO:0005739,malonate-semialdehyde dehydrogenase (acetylating) activity; methylmalonate-semialdehyde dehydrogenase (acylating) activity; mitochondrion,PF00171;,0,CHOYP_EF2.5.5,,,1.00E-96,EE677697.p.cg.6,4,,MMSA_ANOGA,Anopheles gambiae (African malaria mosquito), comp142891_c1_seq1,1778,39.9325,0.46875239,404,1627,,2.00E-133,O75648,Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.-) (MTO2 homolog),Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.14) (MTO2 homolog),GO:0005524; GO:0005739; GO:0016783; GO:0004808; GO:0000049,ATP binding; mitochondrion; sulfurtransferase activity; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity; tRNA binding,,1.00E-36,CHOYP_MTU1.2.2,,,,,,,MTU1_HUMAN,Homo sapiens (Human),mitochondrial tRNA thio-modification [GO:0070903]; tRNA wobble position uridine thiolation [GO:0002143] comp142892_c0_seq4,2917,42.2352,0.48765478,142,89,,0,Q61543,Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160),Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160),GO:0000139; GO:0060349; GO:0031012; GO:0016021; GO:0010955; GO:0030512; GO:0005886; GO:0032330,Golgi membrane; bone morphogenesis; extracellular matrix; integral to membrane; negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; plasma membrane; regulation of chondrocyte differentiation,PF00839;,,,,,,,,,GSLG1_MOUSE,Mus musculus (Mouse),bone morphogenesis [GO:0060349]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of chondrocyte differentiation [GO:0032330] comp142892_c0_seq5,1425,40.7719,0.41101043,2,0,,2.00E-120,Q61543,Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160),Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160),GO:0000139; GO:0060349; GO:0031012; GO:0016021; GO:0010955; GO:0030512; GO:0005886; GO:0032330,Golgi membrane; bone morphogenesis; extracellular matrix; integral to membrane; negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; plasma membrane; regulation of chondrocyte differentiation,PF00839;,,,,,,,,,GSLG1_MOUSE,Mus musculus (Mouse),bone morphogenesis [GO:0060349]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of chondrocyte differentiation [GO:0032330] comp142893_c1_seq10,457,68.4902,0.99109921,0,0,,2.00E-13,P15025,Transposase for insertion sequence element IS21,Transposase for insertion sequence element IS21,GO:0003677; GO:0015074; GO:0006310; GO:0032196,DNA binding; DNA integration; DNA recombination; transposition,PF00665;,,,,,,,,,ISTA_PSEAI,Pseudomonas aeruginosa,DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196] comp142893_c1_seq15,1603,62.1335,0.91935389,0,12,,6.00E-82,Q51649,Putative transposase for insertion sequence IS408,Putative transposase for insertion sequence IS408,GO:0003677; GO:0015074; GO:0006310; GO:0032196,DNA binding; DNA integration; DNA recombination; transposition,PF00665;,,,,,,,,,T408_BURM1,Burkholderia multivorans (strain ATCC 17616 / 249),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196] comp142893_c1_seq17,1153,67.9965,1.00950592,0,0,,4.00E-68,P55923,Insertion sequence IS408 putative ATP-binding protein (ORF2),Insertion sequence IS408 putative ATP-binding protein (ORF2),GO:0005524; GO:0017111,ATP binding; nucleoside-triphosphatase activity,PF01695;PF08483;,,,,,,,,,ISTB_BURM1,Burkholderia multivorans (strain ATCC 17616 / 249), comp142893_c1_seq19,1215,63.4568,1.04846017,0,0,,5.00E-47,Q51649,Putative transposase for insertion sequence IS408,Putative transposase for insertion sequence IS408,GO:0003677; GO:0015074; GO:0006310; GO:0032196,DNA binding; DNA integration; DNA recombination; transposition,PF00665;,,,,,,,,,T408_BURM1,Burkholderia multivorans (strain ATCC 17616 / 249),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196] comp142893_c1_seq5,1281,63.7783,1.05422633,0,0,,3.00E-10,P15025,Transposase for insertion sequence element IS21,Transposase for insertion sequence element IS21,GO:0003677; GO:0015074; GO:0006310; GO:0032196,DNA binding; DNA integration; DNA recombination; transposition,PF00665;,,,,,,,,,ISTA_PSEAI,Pseudomonas aeruginosa,DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196] comp142893_c7_seq1,379,65.6992,0.93198016,0,24,,5.00E-34,P42218,Capsule polysaccharide export protein KpsS,Capsule polysaccharide export protein KpsS,GO:0000271; GO:0015774,polysaccharide biosynthetic process; polysaccharide transport,PF05159;,,,,,,,,,KPSS5_ECOLX,Escherichia coli,polysaccharide biosynthetic process [GO:0000271]; polysaccharide transport [GO:0015774] comp142893_c8_seq1,483,69.7723,0.93944502,0,70,,4.00E-06,Q50700,Putative transposase Rv3428c,Putative transposase Rv3428c,GO:0015074; GO:0005576; GO:0003676; GO:0005886,DNA integration; extracellular region; nucleic acid binding; plasma membrane,PF00665;,,,,,,,,,Y3428_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),DNA integration [GO:0015074] comp142895_c1_seq15,212,35.3774,0.30959991,0,16,,,,,,,,,,,1.00E-11,ruditapes_c12614,,,,,,, comp142896_c0_seq1,4277,35.6558,0.66302285,0,0,,3.00E-53,Q5D0E6,DALR anticodon-binding domain-containing protein 3,DALR anticodon-binding domain-containing protein 3,GO:0005524; GO:0004814; GO:0006420,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation,PF05746;,,,,,,,,,DALD3_HUMAN,Homo sapiens (Human),arginyl-tRNA aminoacylation [GO:0006420] comp142896_c0_seq3,4296,35.7076,0.66544992,0,0,,3.00E-53,Q5D0E6,DALR anticodon-binding domain-containing protein 3,DALR anticodon-binding domain-containing protein 3,GO:0005524; GO:0004814; GO:0006420,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation,PF05746;,,,,,,,,,DALD3_HUMAN,Homo sapiens (Human),arginyl-tRNA aminoacylation [GO:0006420] comp142896_c0_seq4,4263,35.7026,0.65612253,0,0,,2.00E-52,Q6PJN8,DALR anticodon-binding domain-containing protein 3,DALR anticodon-binding domain-containing protein 3,GO:0005524; GO:0004814; GO:0006420,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation,PF05746;,,,,,,,,,DALD3_MOUSE,Mus musculus (Mouse),arginyl-tRNA aminoacylation [GO:0006420] comp142896_c0_seq6,4231,35.4526,0.66293209,0,0,,3.00E-53,Q5D0E6,DALR anticodon-binding domain-containing protein 3,DALR anticodon-binding domain-containing protein 3,GO:0005524; GO:0004814; GO:0006420,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation,PF05746;,,,,,,,,,DALD3_HUMAN,Homo sapiens (Human),arginyl-tRNA aminoacylation [GO:0006420] comp142896_c0_seq7,3720,36.2903,0.64580262,0,0,,1.00E-52,Q6PJN8,DALR anticodon-binding domain-containing protein 3,DALR anticodon-binding domain-containing protein 3,GO:0005524; GO:0004814; GO:0006420,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation,PF05746;,,,,,,,,,DALD3_MOUSE,Mus musculus (Mouse),arginyl-tRNA aminoacylation [GO:0006420] comp142896_c0_seq8,4264,35.4597,0.67240658,0,0,,3.00E-53,Q5D0E6,DALR anticodon-binding domain-containing protein 3,DALR anticodon-binding domain-containing protein 3,GO:0005524; GO:0004814; GO:0006420,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation,PF05746;,,,,,,,,,DALD3_HUMAN,Homo sapiens (Human),arginyl-tRNA aminoacylation [GO:0006420] comp142900_c0_seq1,1491,44.1985,0.56584182,23,11,,,,,,,,,4.00E-17,CHOYP_LOC100371901.1.1,,,,,,,,, comp142900_c0_seq2,3857,39.8756,0.47631244,40,28,,7.00E-35,Q6P9F0,Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa),Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa),GO:0005737; GO:0005634; GO:0005886,cytoplasm; nucleus; plasma membrane,,,,,,,,,,CCD62_HUMAN,Homo sapiens (Human),cellular response to estradiol stimulus [GO:0071392]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp142901_c0_seq1,1426,37.4474,0.28406907,231,2089,,7.00E-31,Q5RCE6,Ribosomal L1 domain-containing protein 1,Ribosomal L1 domain-containing protein 1,GO:0003723; GO:0005730,RNA binding; nucleolus,PF00687;,,,1.00E-34,ruditapes_c18265,,,,,RL1D1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),regulation of apoptotic process [GO:0042981]; regulation of cellular senescence [GO:2000772] comp142903_c1_seq1,528,33.5227,0.40526192,28,102,,,,,,,,,,,8.00E-12,ruditapes_c14814,,,,,,, comp142903_c2_seq3,1669,34.6914,0.35884838,58,76,,,,,,,,,,,3.00E-11,ruditapes_c27792,,,,,,, comp142903_c2_seq5,1569,43.021,0.40105367,120,450,,4.00E-143,Q32PI1,Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1),Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1),GO:0005524; GO:0090166; GO:0005795; GO:0051301; GO:0007067; GO:0005634; GO:0046777; GO:0004674; GO:0005819,ATP binding; Golgi disassembly; Golgi stack; cell division; mitosis; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; spindle,PF00069;,2.00E-52,CHOYP_VRK1.1.1,,,,,,,VRK1_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; Golgi disassembly [GO:0090166]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360] comp142904_c3_seq1,572,41.7832,0.32145961,5,0,,,,,,,,,9.00E-84,CHOYP_LOC100374952.1.1,,,,,,,,, comp142904_c3_seq3,1085,40.4608,0.34310657,13,7,,4.00E-64,Q92546,Retrograde Golgi transport protein RGP1 homolog,RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog),,,PF08737;,,,,,,,,,RGP1_HUMAN,Homo sapiens (Human),"negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]" comp142905_c0_seq1,1544,33.2902,0.94460788,87,93,,2.00E-07,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp142905_c0_seq2,1027,36.0273,0.90556816,3,11,,6.00E-08,Q03278,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO21_NASVI,Nasonia vitripennis (Parasitic wasp), comp142907_c0_seq6,1878,34.4515,0.65107434,17,43,,,,,,,,,,,5.00E-15,ruditapes2_c74,,,,,,, comp142908_c2_seq1,935,32.4064,0.44917598,188,408,,,,,,,,,,,5.00E-11,ruditapes_c5671,,,,,,, comp142909_c1_seq1,3657,42.8493,0.65328711,5,2,,,,,,,,,6.00E-26,CHOYP_DOK7.1.1,,,,,,,,, comp142909_c1_seq2,2716,43.9985,0.63256951,2,6,,2.00E-41,Q18PE1,Protein Dok-7 (Downstream of tyrosine kinase 7),Protein Dok-7 (Downstream of tyrosine kinase 7),GO:0030054; GO:0031594; GO:0007528; GO:0035091; GO:0005886; GO:0061098; GO:0019901; GO:0043113,cell junction; neuromuscular junction; neuromuscular junction development; phosphatidylinositol binding; plasma membrane; positive regulation of protein tyrosine kinase activity; protein kinase binding; receptor clustering,PF02174;,4.00E-26,CHOYP_DOK7.1.1,,,,,,,DOK7_HUMAN,Homo sapiens (Human),positive regulation of protein tyrosine kinase activity [GO:0061098] comp142910_c0_seq1,2384,41.4849,0.99507532,103,320,,1.00E-23,Q641Q3,Meteorin-like protein,Meteorin-like protein (Subfatin),GO:0005576,extracellular region,,,,,,,,,,METRL_HUMAN,Homo sapiens (Human),brown fat cell differentiation [GO:0050873]; fat cell differentiation [GO:0045444]; negative regulation of inflammatory response [GO:0050728]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of energy homeostasis [GO:2000507]; response to cold [GO:0009409]; response to muscle activity [GO:0014850] comp142911_c0_seq1,3272,37.1638,0.3342857,270,809,,5.00E-55,Q99797,Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59),Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59),GO:0046872; GO:0004222; GO:0005759; GO:0005739; GO:0006627; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; mitochondrion; protein processing involved in protein targeting to mitochondrion; proteolysis,PF01432;,,,,,,,,,MIPEP_HUMAN,Homo sapiens (Human),peptide metabolic process [GO:0006518]; protein processing involved in protein targeting to mitochondrion [GO:0006627] comp142911_c0_seq2,3300,37.0909,0.33250938,342,882,,0,P24155,Thimet oligopeptidase (EC 3.4.24.15) (Endo-oligopeptidase A) (Endopeptidase 24.15) (PZ-peptidase) (Soluble metallo-endopeptidase),Thimet oligopeptidase (EC 3.4.24.15) (Endo-oligopeptidase A) (Endopeptidase 24.15) (PZ-peptidase) (Soluble metallo-endopeptidase),GO:0005737; GO:0046872; GO:0004222; GO:0042277; GO:0006508,cytoplasm; metal ion binding; metalloendopeptidase activity; peptide binding; proteolysis,PF01432;,0,CHOYP_THOP1.1.1,4.00E-19,ruditapes_c20158,,,,,THOP1_RAT,Rattus norvegicus (Rat),peptide metabolic process [GO:0006518]; proteolysis [GO:0006508] comp142912_c0_seq2,925,44.8649,0.63326018,33,2,,6.00E-62,Q66IZ5,Transcriptional adapter 3-B (ADA3 homolog B) (Transcriptional adapter 3-like B) (ADA3-like protein B),Transcriptional adapter 3-B (ADA3 homolog B) (Transcriptional adapter 3-like B) (ADA3-like protein B),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10198;,,,,,,,,,TAD3B_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142912_c0_seq3,925,44.973,0.58779897,15,17,,,,,,,,,1.00E-33,CHOYP_TAD3B.1.1,,,,,,,,, comp142913_c0_seq1,2566,40.2962,0.55026148,1226,4347,,8.00E-90,Q5R8W6,Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein),Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein),GO:0003677; GO:0008380; GO:0005685; GO:0003729; GO:0006376; GO:0016607; GO:0005634,DNA binding; RNA splicing; U1 snRNP; mRNA binding; mRNA splice site selection; nuclear speck; nucleus,PF03194;,2.00E-112,CHOYP_LC7L3.1.1,1.00E-118,ruditapes2_c2530,,,,,LC7L3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA splice site selection [GO:0006376]; RNA splicing [GO:0008380] comp142914_c1_seq2,2283,34.8664,0.70365796,0,0,,5.00E-40,Q09912,Protein psi1 (Protein psi),Protein psi1 (Protein psi),GO:0030544; GO:0007049; GO:0034605; GO:0002183; GO:0005829; GO:0005634; GO:0006457,Hsp70 protein binding; cell cycle; cellular response to heat; cytoplasmic translational initiation; cytosol; nucleus; protein folding,PF00226;PF01556;,3.00E-110,CHOYP_LOC752244.2.2,,,,,,,PSI1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translational initiation [GO:0002183]; protein folding [GO:0006457] comp142914_c1_seq3,2429,35.1173,0.67633023,2,18,,4.00E-73,O75953,DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40),DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40),GO:0005829; GO:0000122; GO:0005634; GO:0006457; GO:0006986,cytosol; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein folding; response to unfolded protein,PF00226;PF01556;,,,,,,,,,DNJB5_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986] comp142914_c1_seq4,2334,34.8329,0.68807183,5,25,,6.00E-40,Q09912,Protein psi1 (Protein psi),Protein psi1 (Protein psi),GO:0030544; GO:0007049; GO:0034605; GO:0002183; GO:0005829; GO:0005634; GO:0006457,Hsp70 protein binding; cell cycle; cellular response to heat; cytoplasmic translational initiation; cytosol; nucleus; protein folding,PF00226;PF01556;,,,,,,,,,PSI1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translational initiation [GO:0002183]; protein folding [GO:0006457] comp142914_c1_seq5,2405,35.1767,0.68073801,0,6,,4.00E-73,O75953,DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40),DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40),GO:0005829; GO:0000122; GO:0005634; GO:0006457; GO:0006986,cytosol; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein folding; response to unfolded protein,PF00226;PF01556;,7.00E-23,CHOYP_LOC100377412.1.1,1.00E-24,ruditapes2_c577,,,,,DNJB5_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986] comp142917_c0_seq1,5013,42.9882,0.47396498,90,18,,0,Q96RY7,Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2),Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2),GO:0042384; GO:0035085; GO:0036064; GO:0030991; GO:0032391,cilium assembly; cilium axoneme; cilium basal body; intraflagellar transport particle A; photoreceptor connecting cilium,,0,CHOYP_IFT140.1.1,,,,,,,IF140_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; limb morphogenesis [GO:0035108]; neural tube patterning [GO:0021532]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589]; renal system development [GO:0072001]; retina development in camera-type eye [GO:0060041]; skeletal system morphogenesis [GO:0048705] comp142917_c0_seq4,4229,45.1643,0.4731175,4,0,,0,Q96RY7,Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2),Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2),GO:0042384; GO:0035085; GO:0036064; GO:0030991; GO:0032391,cilium assembly; cilium axoneme; cilium basal body; intraflagellar transport particle A; photoreceptor connecting cilium,,0,CHOYP_IFT140.1.1,,,,,,,IF140_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; limb morphogenesis [GO:0035108]; neural tube patterning [GO:0021532]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589]; renal system development [GO:0072001]; retina development in camera-type eye [GO:0060041]; skeletal system morphogenesis [GO:0048705] comp142920_c0_seq1,6041,38.7022,0.81311603,0,0,,2.00E-49,Q69Z37,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_MOUSE,Mus musculus (Mouse),common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145] comp142920_c0_seq2,5465,37.2553,0.87143782,0,0,,8.00E-48,Q8IVG5,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_HUMAN,Homo sapiens (Human), comp142920_c0_seq3,4812,38.2585,0.81488116,0,0,,1.00E-49,Q69Z37,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_MOUSE,Mus musculus (Mouse),common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145] comp142920_c0_seq4,6694,37.8399,0.85847323,0,0,,9.00E-48,Q8IVG5,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_HUMAN,Homo sapiens (Human), comp142920_c0_seq5,5788,38.2516,0.81004589,0,0,,2.00E-49,Q69Z37,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_MOUSE,Mus musculus (Mouse),common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145] comp142920_c0_seq6,4559,37.6837,0.81580418,0,0,,1.00E-49,Q69Z37,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_MOUSE,Mus musculus (Mouse),common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145] comp142921_c0_seq1,4357,35.2536,0.74679609,1588,5322,,0,Q5GIS3,Guanine nucleotide-binding protein subunit beta (pfGbeta1) (G protein subunit beta-1),Guanine nucleotide-binding protein subunit beta (pfGbeta1) (G protein subunit beta-1),GO:0005737; GO:0004871,cytoplasm; signal transducer activity,PF00400;,0,CHOYP_LOC100368865.1.1,,,,,,,GBB_PINFU,Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata), comp142922_c0_seq10,1401,40.3283,0.47795897,0,0,,1.00E-07,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp142922_c0_seq11,1485,40.6734,0.47766013,6,0,,7.00E-07,Q55E58,Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),GO:0005524; GO:0005525; GO:0042641; GO:0000281; GO:0004721; GO:0006470; GO:0004674; GO:0007264,ATP binding; GTP binding; actomyosin; mitotic cytokinesis; phosphoprotein phosphatase activity; protein dephosphorylation; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF16095;PF06602;PF07714;PF08477;,,,,,,,,,PATS1_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176] comp142922_c0_seq2,1488,39.7177,0.44131614,0,0,,3.00E-07,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp142923_c1_seq1,2473,35.4226,0.28449421,80,712,,5.00E-17,Q567G6,Uncharacterized protein C3orf17 homolog,Protein nepro homolog,GO:0016021,integral to membrane,PF14780;,,,,,,,,,CC017_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of neuron differentiation [GO:0045665]; positive regulation of Notch signaling pathway [GO:0045747] comp142924_c1_seq3,2093,42.1882,0.43046572,19,24,,3.00E-11,Q61SK8,MOG interacting and ectopic P-granules protein 1 (Nuclear zinc finger protein),MOG interacting and ectopic P-granules protein 1 (Nuclear zinc finger protein),GO:0017151; GO:0003723; GO:0030154; GO:0007506; GO:0040035; GO:0042826; GO:0046872; GO:0002119; GO:0005634; GO:0008134,DEAD/H-box RNA helicase binding; RNA binding; cell differentiation; gonadal mesoderm development; hermaphrodite genitalia development; histone deacetylase binding; metal ion binding; nematode larval development; nucleus; transcription factor binding,,,,,,,,,,MEP1_CAEBR,Caenorhabditis briggsae,cell differentiation [GO:0030154]; gonadal mesoderm development [GO:0007506]; hermaphrodite genitalia development [GO:0040035]; nematode larval development [GO:0002119] comp142924_c1_seq4,1978,42.4166,0.43984305,0,0,,1.00E-13,Q21502,MOG interacting and ectopic P-granules protein 1 (Nuclear zinc finger protein),MOG interacting and ectopic P-granules protein 1 (Nuclear zinc finger protein),GO:0003723; GO:0008406; GO:0007506; GO:0040035; GO:0046872; GO:0005634; GO:0048599; GO:0010468; GO:0040025,RNA binding; gonad development; gonadal mesoderm development; hermaphrodite genitalia development; metal ion binding; nucleus; oocyte development; regulation of gene expression; vulval development,,,,,,,,,,MEP1_CAEEL,Caenorhabditis elegans,gonadal mesoderm development [GO:0007506]; gonad development [GO:0008406]; hermaphrodite genitalia development [GO:0040035]; nematode larval development [GO:0002119]; oocyte development [GO:0048599]; regulation of gene expression [GO:0010468]; vulval development [GO:0040025] comp142926_c0_seq1,3445,33.3817,0.62619636,29,0,,6.00E-54,Q498J5,Mitochondria-eating protein (Spermatogenesis-associated protein 18),Mitochondria-eating protein (Spermatogenesis-associated protein 18),GO:0005741; GO:0035694; GO:0035695; GO:0006974,mitochondrial outer membrane; mitochondrial protein catabolic process; mitochondrion degradation by induced vacuole formation; response to DNA damage stimulus,PF16026;,,,,,,,,,MIEAP_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; mitochondrial protein catabolic process [GO:0035694]; mitophagy by induced vacuole formation [GO:0035695] comp142926_c0_seq3,4064,35.1378,0.66185605,200,8,,5.00E-107,Q503Q1,Mitochondria-eating protein (Spermatogenesis-associated protein 18),Mitochondria-eating protein (Spermatogenesis-associated protein 18),GO:0005741; GO:0035694; GO:0035695; GO:0006974,mitochondrial outer membrane; mitochondrial protein catabolic process; mitochondrion degradation by induced vacuole formation; response to DNA damage stimulus,PF16026;,1.00E-161,CHOYP_BRAFLDRAFT_204736.1.2,,,,,,,MIEAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; mitochondrial protein catabolic process [GO:0035694]; mitophagy by induced vacuole formation [GO:0035695] comp142929_c0_seq1,3950,40.8354,0.83321864,56,6,,1.00E-24,Q76NV1,Probable serine/threonine-protein kinase dyrk1 (EC 2.7.12.1) (Dual specificity tyrosine-phosphorylation regulated kinase 1),Probable serine/threonine-protein kinase dyrk1 (EC 2.7.12.1) (Dual specificity tyrosine-phosphorylation regulated kinase 1),GO:0005524; GO:0004674; GO:0004712,ATP binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity,PF00069;,,,,,,,,,DYRK1_DICDI,Dictyostelium discoideum (Slime mold), comp142929_c0_seq2,3573,41.8136,0.82022107,56,0,,3.00E-152,Q3UTQ8,Cyclin-dependent kinase-like 5 (EC 2.7.11.22),Cyclin-dependent kinase-like 5 (EC 2.7.11.22),GO:0005524; GO:0004693; GO:0005737; GO:0016301; GO:0005634; GO:0046777,ATP binding; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; kinase activity; nucleus; protein autophosphorylation,PF00069;,8.00E-170,CHOYP_CDKL5.1.1,,,,,,,CDKL5_MOUSE,Mus musculus (Mouse),neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777] comp142930_c0_seq1,2495,40.2405,0.45792571,3576,177,,0,P50544,"Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (EC 1.3.8.9) (MVLCAD) (VLCAD)","Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (EC 1.3.8.9) (MVLCAD) (VLCAD)",GO:0003995; GO:0033539; GO:0050660; GO:0005743; GO:0005739; GO:0045717; GO:0046322; GO:0090181; GO:0001659,acyl-CoA dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA dehydrogenase; flavin adenine dinucleotide binding; mitochondrial inner membrane; mitochondrion; negative regulation of fatty acid biosynthetic process; negative regulation of fatty acid oxidation; regulation of cholesterol metabolic process; temperature homeostasis,PF00441;PF02770;PF02771;,0,CHOYP_LOC100369524.1.1,8.00E-52,ruditapes_c10315,,,,,ACADV_MOUSE,Mus musculus (Mouse),epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of fatty acid oxidation [GO:0046322]; regulation of cholesterol metabolic process [GO:0090181]; temperature homeostasis [GO:0001659]; very long-chain fatty acid catabolic process [GO:0042760] comp142932_c0_seq1,2355,44.0764,0.37908293,0,0,,,,,,,,,4.00E-89,CHOYP_BRAFLDRAFT_121884.1.1,,,,,,,,, comp142932_c0_seq8,2367,44.191,0.39274664,0,0,,,,,,,,,2.00E-87,CHOYP_BRAFLDRAFT_121884.1.1,,,,,,,,, comp142933_c0_seq1,1467,37.287,0.33678828,278,1095,,4.00E-79,Q8N1B3,Cyclin-related protein FAM58A (Cyclin-M),Cyclin-related protein FAM58A (CDK10-activating cyclin) (Cyclin-M),GO:0000079; GO:0006355,"regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-dependent",PF00134;,8.00E-20,CHOYP_FA58A.1.1,,,,,,,FA58A_HUMAN,Homo sapiens (Human),positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp142936_c0_seq1,3338,43.1096,0.41634409,544,473,,3.00E-15,Q99MV7,RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007286; GO:0008270,"cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatid development; zinc ion binding",PF00567;,,,,,,,,,RNF17_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp142936_c2_seq1,2855,39.5797,0.36344552,326,340,,6.00E-41,Q9BXT4,Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1),Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1),GO:0043046; GO:0033391; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; chromatoid body; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_HUMAN,Homo sapiens (Human),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp142938_c0_seq3,677,45.4948,1.17212265,64,410,,1.00E-78,A4IF97,"Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2)","Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2)",GO:0030018; GO:0045177; GO:0005509; GO:0016460; GO:0008360; GO:0001725,Z disc; apical part of cell; calcium ion binding; myosin II complex; regulation of cell shape; stress fiber,PF08976;PF13405;,1.00E-82,CHOYP_ML12B.1.1,7.00E-14,ruditapes_c25923,,,,,ML12B_BOVIN,Bos taurus (Bovine),regulation of cell shape [GO:0008360] comp142939_c0_seq1,923,38.2449,0.83243341,90,71,,2.00E-17,Q86YG4,5'-nucleotidase domain-containing protein 4,5'-nucleotidase domain-containing protein 4,GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF05761;,1.00E-47,CHOYP_LOC100376076.1.1,,,,,,,NT5D4_HUMAN,Homo sapiens (Human), comp142939_c1_seq3,1411,38.6251,0.5337368,22,8,,3.00E-86,Q9H857,5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-),5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF05761;,,,,,,,,,NT5D2_HUMAN,Homo sapiens (Human), comp142939_c1_seq5,429,37.0629,0.40900666,8,0,,2.00E-27,Q9H857,5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-),5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-),GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF05761;,8.00E-26,CHOYP_LOC100376076.1.1,,,,,,,NT5D2_HUMAN,Homo sapiens (Human), comp142941_c1_seq1,3491,43.9989,0.4194427,6,60,,3.00E-11,Q8IWY4,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0007512; GO:0007596; GO:0005509; GO:0045446; GO:0009897; GO:0005615; GO:0019897; GO:0042802; GO:0006954; GO:0009791; GO:0046982; GO:0051260,adult heart development; blood coagulation; calcium ion binding; endothelial cell differentiation; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; identical protein binding; inflammatory response; post-embryonic development; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_HUMAN,Homo sapiens (Human),adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260] comp142941_c1_seq3,2304,43.5764,0.38662637,5,58,,1.00E-11,Q8IWY4,"Signal peptide, CUB and EGF-like domain-containing protein 1","Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0007512; GO:0007596; GO:0005509; GO:0045446; GO:0009897; GO:0005615; GO:0019897; GO:0042802; GO:0006954; GO:0009791; GO:0046982; GO:0051260,adult heart development; blood coagulation; calcium ion binding; endothelial cell differentiation; external side of plasma membrane; extracellular space; extrinsic to plasma membrane; identical protein binding; inflammatory response; post-embryonic development; protein heterodimerization activity; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB1_HUMAN,Homo sapiens (Human),adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260] comp142941_c1_seq5,1947,45.095,0.43911326,0,0,,3.00E-11,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp142941_c2_seq2,632,43.038,0.41574183,13,34,,7.00E-15,Q66PY1,"Signal peptide, CUB and EGF-like domain-containing protein 3","Signal peptide, CUB and EGF-like domain-containing protein 3",GO:0005509; GO:0009986; GO:0005576; GO:0051291; GO:0051260,calcium ion binding; cell surface; extracellular region; protein heterooligomerization; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB3_MOUSE,Mus musculus (Mouse),protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] comp142942_c4_seq1,1162,33.3907,0.19321626,68,542,,5.00E-46,O09053,Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-),Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-),GO:0008408; GO:0005524; GO:0043140; GO:0006310; GO:0006260; GO:0000731; GO:0051880; GO:0032389; GO:0000403; GO:0006284; GO:0000405; GO:0071480; GO:0009267; GO:0005813; GO:0006302; GO:0009378; GO:0000287; GO:0030145; GO:0010259; GO:0005730; GO:0032066; GO:0005654; GO:0051345; GO:0042981; GO:0040009; GO:0031297; GO:0001302; GO:0010225; GO:0006979; GO:0000723,3'-5' exonuclease activity; ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA recombination; DNA replication; DNA synthesis involved in DNA repair; G-quadruplex DNA binding; MutLalpha complex; Y-form DNA binding; base-excision repair; bubble DNA binding; cellular response to gamma radiation; cellular response to starvation; centrosome; double-strand break repair; four-way junction helicase activity; magnesium ion binding; manganese ion binding; multicellular organismal aging; nucleolus; nucleolus to nucleoplasm transport; nucleoplasm; positive regulation of hydrolase activity; regulation of apoptotic process; regulation of growth rate; replication fork processing; replicative cell aging; response to UV-C; response to oxidative stress; telomere maintenance,PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;,,,,,,,,,WRN_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp142945_c1_seq1,1524,41.4698,0.3667079,137,1153,,9.00E-22,Q9M9E8,F-box protein At1g78280,F-box protein At1g78280,GO:0005829; GO:0016772,"cytosol; transferase activity, transferring phosphorus-containing groups",PF01636;PF00646;,2.00E-21,CHOYP_BRAFLDRAFT_84996.1.1,,,,,,,FB92_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp142951_c0_seq1,359,37.883,0.56250436,26,93,,1.00E-24,Q8IVW1,ADP-ribosylation factor-like protein 17 (ADP-ribosylation factor 7 variant),ADP-ribosylation factor-like protein 17 (ADP-ribosylation factor 7 variant),GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;PF15840;,1.00E-47,CHOYP_ARF4.1.2,2.00E-42,ruditapes_c30520,,,,,ARL17_HUMAN,Homo sapiens (Human),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp142951_c1_seq2,1115,36.861,0.37333363,89,277,,6.00E-63,P51821,ADP-ribosylation factor 1,ADP-ribosylation factor 1,GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,2.00E-12,CHOYP_ACT.15.27,1.00E-38,ruditapes_c4018,,,,,ARF1_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp142953_c1_seq3,1592,35.804,0.4783247,162,752,,7.00E-35,O95295,SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein),SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein),GO:0031083; GO:0005794; GO:0000139; GO:0000149; GO:0008089; GO:0048490; GO:0030054; GO:0006886; GO:0032438; GO:0019048; GO:0043005; GO:0031175; GO:0005730; GO:0048471; GO:0008021; GO:0016079; GO:0031629; GO:0016188; GO:0030672; GO:0072553,BLOC-1 complex; Golgi apparatus; Golgi membrane; SNARE binding; anterograde axon cargo transport; anterograde synaptic vesicle transport; cell junction; intracellular protein transport; melanosome organization; modulation by virus of host morphology or physiology; neuron projection; neuron projection development; nucleolus; perinuclear region of cytoplasm; synaptic vesicle; synaptic vesicle exocytosis; synaptic vesicle fusion to presynaptic membrane; synaptic vesicle maturation; synaptic vesicle membrane; terminal button organization,PF14712;,8.00E-39,CHOYP_BRAFLDRAFT_118250.1.1,,,,,,,SNAPN_HUMAN,Homo sapiens (Human),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; negative regulation of neuron projection development [GO:0010977]; neuron projection development [GO:0031175]; neurotransmitter secretion [GO:0007269]; positive regulation of late endosome to lysosome transport [GO:1902824]; regulation of protein binding [GO:0043393]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; terminal button organization [GO:0072553]; viral process [GO:0016032] comp142954_c0_seq2,1294,39.4127,0.55198631,25,27,,1.00E-59,Q8BKE6,Cytochrome P450 20A1 (EC 1.14.-.-),Cytochrome P450 20A1 (EC 1.14.-.-),GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705,"heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP20A_MOUSE,Mus musculus (Mouse), comp142954_c0_seq3,811,42.91,0.48858507,29,0,,1.00E-29,Q27594,Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9),Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9),GO:0009055; GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"electron carrier activity; endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,2.00E-69,CHOYP_ISCW_ISCW001592.2.2,,,,,,,CP6A9_DROME,Drosophila melanogaster (Fruit fly),insecticide catabolic process [GO:0046701]; insecticide metabolic process [GO:0017143]; response to DDT [GO:0046680] comp142954_c0_seq4,1408,40.0568,0.5233225,46,263,,3.00E-60,Q8BKE6,Cytochrome P450 20A1 (EC 1.14.-.-),Cytochrome P450 20A1 (EC 1.14.-.-),GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705,"heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CP20A_MOUSE,Mus musculus (Mouse), comp142954_c0_seq7,1038,40.1734,0.43899388,28,136,,1.00E-27,Q9V4U7,Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14),Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,2.00E-58,CHOYP_ISCW_ISCW001592.2.2,,,,,,,C6A14_DROME,Drosophila melanogaster (Fruit fly),insecticide catabolic process [GO:0046701]; response to DDT [GO:0046680] comp142956_c0_seq1,744,42.7419,1.01352616,0,19,,4.00E-18,P12812,Major egg antigen (p40),Major egg antigen (p40),,,PF00011;,,,,,,,,,P40_SCHMA,Schistosoma mansoni (Blood fluke), comp142956_c0_seq3,656,44.0549,1.08574181,0,4,,3.00E-18,P12812,Major egg antigen (p40),Major egg antigen (p40),,,PF00011;,,,,,,,,,P40_SCHMA,Schistosoma mansoni (Blood fluke), comp142956_c0_seq6,1945,36.4524,1.09313589,0,0,,1.00E-08,P06582,Heat shock protein Hsp-16.2,Heat shock protein Hsp-16.2,GO:0005737; GO:0006950,cytoplasm; response to stress,PF00011;,,,,,,,,,HSP12_CAEEL,Caenorhabditis elegans,response to heat [GO:0009408] comp142957_c0_seq1,1755,39.7721,0.56540676,0,34,,1.00E-164,O43615,Mitochondrial import inner membrane translocase subunit TIM44,Mitochondrial import inner membrane translocase subunit TIM44,GO:0005524; GO:0015450; GO:0044267; GO:0005743; GO:0005759; GO:0006626,ATP binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; cellular protein metabolic process; mitochondrial inner membrane; mitochondrial matrix; protein targeting to mitochondrion,PF04280;,,,,,,,,,TIM44_HUMAN,Homo sapiens (Human),protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] comp142957_c0_seq2,1740,39.8851,0.56581601,5,0,,2.00E-42,O60084,Mitochondrial import inner membrane translocase subunit tim44,Mitochondrial import inner membrane translocase subunit tim44,GO:0005524; GO:0015450; GO:0005759; GO:0001405; GO:0030150,ATP binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; mitochondrial matrix; presequence translocase-associated import motor; protein import into mitochondrial matrix,PF04280;,,,,,,,,,TIM44_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein import into mitochondrial matrix [GO:0030150] comp142957_c0_seq3,1749,39.9085,0.57625169,4,17,,1.00E-164,O43615,Mitochondrial import inner membrane translocase subunit TIM44,Mitochondrial import inner membrane translocase subunit TIM44,GO:0005524; GO:0015450; GO:0044267; GO:0005743; GO:0005759; GO:0006626,ATP binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; cellular protein metabolic process; mitochondrial inner membrane; mitochondrial matrix; protein targeting to mitochondrion,PF04280;,,,,,,,,,TIM44_HUMAN,Homo sapiens (Human),protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] comp142957_c0_seq4,1411,41.8143,0.6418185,0,5,,,,,,,,,3.00E-24,CHOYP_MCEE.1.1,,,,,,,,, comp142958_c3_seq1,1145,43.4061,0.30276434,103,413,,4.00E-106,Q9CYF5,Williams-Beuren syndrome chromosomal region 16 protein homolog,Williams-Beuren syndrome chromosomal region 16 protein homolog,GO:0005087; GO:0005739,Ran guanyl-nucleotide exchange factor activity; mitochondrion,PF00415;,,,,,,,,,WBS16_MOUSE,Mus musculus (Mouse), comp142960_c0_seq1,2395,36.5762,0.47921269,2243,1231,,2.00E-89,Q5F339,Cytochrome c-type heme lyase (CCHL) (EC 4.4.1.17) (Holocytochrome c-type synthase),Cytochrome c-type heme lyase (CCHL) (EC 4.4.1.17) (Holocytochrome c-type synthase),GO:0004408; GO:0046872; GO:0005743,holocytochrome-c synthase activity; metal ion binding; mitochondrial inner membrane,PF01265;,2.00E-48,CHOYP_CCHL.2.2,7.00E-33,ruditapes2_c458,,,,,CCHL_CHICK,Gallus gallus (Chicken), comp142961_c0_seq1,2915,37.7702,0.95282177,508,1891,,7.00E-95,Q9GKX2,Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (rabNRDR) (Fragment),Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (rabNRDR) (Fragment),GO:0004090; GO:0005739; GO:0005777,carbonyl reductase (NADPH) activity; mitochondrion; peroxisome,,,,2.00E-79,ruditapes_c14612,,,,,DHRS4_RABIT,Oryctolagus cuniculus (Rabbit), comp142962_c0_seq1,260,46.5385,0.35773556,3,21,,9.00E-41,Q9Y4D1,Disheveled-associated activator of morphogenesis 1,Disheveled-associated activator of morphogenesis 1,GO:0030036; GO:0005737; GO:0005886; GO:0001725,actin cytoskeleton organization; cytoplasm; plasma membrane; stress fiber,PF06367;PF06371;PF02181;,2.00E-30,CHOYP_LOC658864.1.1,,,,,,,DAAM1_HUMAN,Homo sapiens (Human),"actin cytoskeleton organization [GO:0030036]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp142962_c1_seq1,2141,46.7539,0.54306745,28,97,,2.00E-98,Q924T7,E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31),E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31),GO:0035631; GO:0023035; GO:0071797; GO:0050852; GO:0005829; GO:0009898; GO:0043123; GO:0051092; GO:0097039; GO:0043130; GO:0004842; GO:0008270,CD40 receptor complex; CD40 signaling pathway; LUBAC complex; T cell receptor signaling pathway; cytosol; internal side of plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; protein linear polyubiquitination; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding,PF16678;PF01485;PF09409;,2.00E-54,CHOYP_LOC100375820.1.1,,,,,,,RNF31_MOUSE,Mus musculus (Mouse),CD40 signaling pathway [GO:0023035]; negative regulation of necroptotic process [GO:0060546]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; T cell receptor signaling pathway [GO:0050852] comp142964_c1_seq6,1013,42.9418,0.3215648,0,0,,4.00E-25,Q6UVJ0,Spindle assembly abnormal protein 6 homolog (HsSAS-6),Spindle assembly abnormal protein 6 homolog (HsSAS-6),GO:0005814; GO:0007099,centriole; centriole replication,PF16531;,,,,,,,,,SAS6_HUMAN,Homo sapiens (Human),centriole replication [GO:0007099]; centrosome duplication [GO:0051298] comp142964_c1_seq9,971,43.2544,0.33062009,0,0,,3.00E-32,Q7ZVT3,Spindle assembly abnormal protein 6 homolog,Spindle assembly abnormal protein 6 homolog,GO:0005813; GO:0051298; GO:0005737; GO:0040016; GO:0007052; GO:0000280; GO:0007283,centrosome; centrosome duplication; cytoplasm; embryonic cleavage; mitotic spindle organization; nuclear division; spermatogenesis,PF16531;,3.00E-54,CHOYP_LOC100376181.1.1,,,,,,,SAS6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; embryonic cleavage [GO:0040016]; mitotic spindle organization [GO:0007052]; nuclear division [GO:0000280]; spermatogenesis [GO:0007283] comp142966_c0_seq1,1384,45.448,0.4246124,0,0,,0,P55931,"Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)","Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)",GO:0051539; GO:0009055; GO:0022900; GO:0004174; GO:0050660; GO:0016020; GO:0046872; GO:0005743; GO:0005739; GO:0043783; GO:0006979; GO:0048039,"4 iron, 4 sulfur cluster binding; electron carrier activity; electron transport chain; electron-transferring-flavoprotein dehydrogenase activity; flavin adenine dinucleotide binding; membrane; metal ion binding; mitochondrial inner membrane; mitochondrion; oxidoreductase activity, oxidizing metal ions with flavin as acceptor; response to oxidative stress; ubiquinone binding",PF05187;,3.00E-176,CHOYP_ETFD.1.1,,,,,,,ETFD_PIG,Sus scrofa (Pig),electron transport chain [GO:0022900]; response to oxidative stress [GO:0006979] comp142966_c0_seq4,2865,41.0471,0.37631417,26,95,,0,Q2KIG0,"Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)","Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)",GO:0051539; GO:0009055; GO:0022900; GO:0004174; GO:0033539; GO:0031305; GO:0046872; GO:0006979; GO:0048039,"4 iron, 4 sulfur cluster binding; electron carrier activity; electron transport chain; electron-transferring-flavoprotein dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA dehydrogenase; integral to mitochondrial inner membrane; metal ion binding; response to oxidative stress; ubiquinone binding",PF05187;,0,CHOYP_ETFD.1.1,,,,,,,ETFD_BOVIN,Bos taurus (Bovine),electron transport chain [GO:0022900]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to oxidative stress [GO:0006979] comp142969_c0_seq2,2856,37.535,0.41419418,491,3201,,7.00E-138,Q6AZA0,"Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)","Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)",GO:0003985; GO:0046872; GO:0005739,acetyl-CoA C-acetyltransferase activity; metal ion binding; mitochondrion,PF02803;PF00108;,3.00E-173,CHOYP_BRAFLDRAFT_268929.1.1,,,,,,,THIL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),metabolic process [GO:0008152] comp142971_c0_seq1,4672,44.5205,0.46714111,2803,192,,0,Q96MT7,WD repeat-containing protein 52,Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52),,,PF00400;,0,CHOYP_WDR52.1.1,,,,,,,WDR52_HUMAN,Homo sapiens (Human), comp142972_c0_seq1,1520,36.5132,0.7754121,0,0,,3.00E-34,Q6PBU0,Protein FAM136A,Protein FAM136A,GO:0005739,mitochondrion,PF05811;,,,,,,,,,F136A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142972_c0_seq3,1509,36.5805,0.7780218,0,0,,3.00E-34,Q6PBU0,Protein FAM136A,Protein FAM136A,GO:0005739,mitochondrion,PF05811;,,,,,,,,,F136A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp142973_c0_seq1,983,45.2696,0.39899482,3,0,,5.00E-09,Q5VXM1,CUB domain-containing protein 2,CUB domain-containing protein 2,GO:0005576,extracellular region,PF00431;,,,,,,,,,CDCP2_HUMAN,Homo sapiens (Human), comp142973_c0_seq2,2566,44.4661,0.49740725,175,105,,2.00E-09,Q9JLB4,Cubilin (Intrinsic factor-cobalamin receptor),Cubilin (Intrinsic factor-cobalamin receptor),GO:0005794; GO:0016324; GO:0005903; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0030139; GO:0005783; GO:0005768; GO:0010008; GO:0042953; GO:0005765; GO:0004872; GO:0006898,Golgi apparatus; apical plasma membrane; brush border; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; endocytic vesicle; endoplasmic reticulum; endosome; endosome membrane; lipoprotein transport; lysosomal membrane; receptor activity; receptor-mediated endocytosis,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898] comp142974_c0_seq2,3591,37.037,0.69974031,49,19,,,,,,,,,2.00E-25,CHOYP_DDX46.1.1,,,,,,,,, comp142975_c0_seq2,1347,42.6875,0.30997524,106,75,,2.00E-39,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp142976_c0_seq1,3629,43.6484,0.5757662,679,3994,,0,P49696,Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS),GO:0005524; GO:0002161; GO:0005737; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00043;PF00133;PF10458;,0,CHOYP_BRAFLDRAFT_66627.1.1,,,,,,,SYVC_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),valyl-tRNA aminoacylation [GO:0006438] comp142978_c0_seq1,2894,36.7657,0.34975699,126,954,,,,,,,,,1.00E-166,CHOYP_SYAC.2.2,,,,,,,,, comp142978_c0_seq2,2856,36.9048,0.36192704,406,208,,5.00E-46,Q7A7L2,Probable acetyl-CoA acyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase),Probable acetyl-CoA acyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase),GO:0003985; GO:0005737,acetyl-CoA C-acetyltransferase activity; cytoplasm,PF02803;PF00108;,1.00E-166,CHOYP_SYAC.2.2,,,,,,,THLA_STAAN,Staphylococcus aureus (strain N315),metabolic process [GO:0008152] comp142978_c0_seq3,2825,37.0973,0.36223476,26,414,,0,O46629,"Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)]","Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)]",GO:0003988; GO:0005783; GO:0006635; GO:0016509; GO:0005743; GO:0042645; GO:0005741,acetyl-CoA C-acyltransferase activity; endoplasmic reticulum; fatty acid beta-oxidation; long-chain-3-hydroxyacyl-CoA dehydrogenase activity; mitochondrial inner membrane; mitochondrial nucleoid; mitochondrial outer membrane,PF02803;PF00108;,,,,,,,,,ECHB_BOVIN,Bos taurus (Bovine),fatty acid beta-oxidation [GO:0006635] comp142979_c0_seq1,972,40.2263,0.4860145,0,0,,1.00E-08,O54960,Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein),Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein),GO:0030165; GO:0005737; GO:1901215; GO:0031102; GO:0007269; GO:0050998; GO:0005634; GO:0042981; GO:0045428; GO:0050999,PDZ domain binding; cytoplasm; negative regulation of neuron death; neuron projection regeneration; neurotransmitter secretion; nitric-oxide synthase binding; nucleus; regulation of apoptotic process; regulation of nitric oxide biosynthetic process; regulation of nitric-oxide synthase activity,PF00640;,,,,,,,,,CAPON_RAT,Rattus norvegicus (Rat),negative regulation of neuron death [GO:1901215]; neuron projection regeneration [GO:0031102]; neurotransmitter secretion [GO:0007269]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; regulation of apoptotic process [GO:0042981]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of nitric-oxide synthase activity [GO:0050999] comp142979_c0_seq4,2751,35.2236,0.4847569,158,481,,4.00E-47,Q801G1,Low density lipoprotein receptor adapter protein 1-A (Autosomal recessive hypercholesterolemia protein homolog alpha) (ARH alpha) (xARH alpha) (Phosphotyrosine-binding protein) (Xcat4),Low density lipoprotein receptor adapter protein 1-A (Autosomal recessive hypercholesterolemia protein homolog alpha) (ARH alpha) (xARH alpha) (Phosphotyrosine-binding protein) (Xcat4),GO:0008203; GO:0005737; GO:0006897,cholesterol metabolic process; cytoplasm; endocytosis,PF00640;,,,,,,,,,ARHA_XENLA,Xenopus laevis (African clawed frog),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897] comp142980_c0_seq1,1132,36.2191,1.06369694,66,17,,2.00E-07,Q8WYR4,Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein),Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein),GO:0005829; GO:0007126; GO:0005634,cytosol; meiosis; nucleus,PF02493;,,,,,,,,,RSPH1_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] comp142980_c0_seq3,871,38.2319,1.05399011,10,8,,6.00E-21,Q6UL01,MORN repeat-containing protein 2 (MORN motif protein in testis),MORN repeat-containing protein 2 (MORN motif protein in testis),,,PF02493;,2.00E-19,CHOYP_BRAFLDRAFT_246978.1.1,,,,,,,MORN2_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] comp142981_c1_seq2,571,42.3818,0.78158332,38,213,,9.00E-25,Q4R6W9,snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit),snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09808;,,,,,,,,,SNPC1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142982_c0_seq1,3172,45.2711,0.49698202,0,0,,0,P61406,Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A),Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A),GO:0000781; GO:0005829; GO:0004521; GO:0046872; GO:0000184; GO:0005730; GO:0005634; GO:0000723; GO:0042162,"chromosome, telomeric region; cytosol; endoribonuclease activity; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleolus; nucleus; telomere maintenance; telomeric DNA binding",PF10374;PF10373;PF13638;,2.00E-100,CHOYP_EST1A.1.1,,,,,,,EST1A_MOUSE,Mus musculus (Mouse),"negative regulation of telomere capping [GO:1904354]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; telomere maintenance [GO:0000723]" comp142982_c0_seq4,5150,44.6214,0.49703287,0,0,,,,,,,,,3.00E-100,CHOYP_EST1A.1.1,,,,,,,,, comp142982_c0_seq6,3312,45.1087,0.49221547,4,0,,0,P61406,Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A),Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A),GO:0000781; GO:0005829; GO:0004521; GO:0046872; GO:0000184; GO:0005730; GO:0005634; GO:0000723; GO:0042162,"chromosome, telomeric region; cytosol; endoribonuclease activity; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleolus; nucleus; telomere maintenance; telomeric DNA binding",PF10374;PF10373;PF13638;,2.00E-100,CHOYP_EST1A.1.1,,,,,,,EST1A_MOUSE,Mus musculus (Mouse),"negative regulation of telomere capping [GO:1904354]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; telomere maintenance [GO:0000723]" comp142985_c0_seq1,2343,37.6867,0.41518721,1029,6595,,4.00E-163,Q9D1M0,Protein SEC13 homolog (SEC13-like protein 1) (SEC13-related protein),Protein SEC13 homolog (SEC13-like protein 1) (SEC13-related protein),GO:0012507; GO:0006888; GO:0005783; GO:0005789; GO:0000776; GO:0051028; GO:0031080; GO:0015031,ER to Golgi transport vesicle membrane; ER to Golgi vesicle-mediated transport; endoplasmic reticulum; endoplasmic reticulum membrane; kinetochore; mRNA transport; nuclear pore outer ring; protein transport,PF00400;,5.00E-151,CHOYP_SEC13.1.1,,,,,,,SEC13_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; mRNA transport [GO:0051028]; positive regulation of TOR signaling [GO:0032008]; protein transport [GO:0015031] comp142987_c0_seq2,1675,37.5522,0.6269667,477,1169,,7.00E-68,A8X4W9,Probable sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3),Probable sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3),GO:0006813; GO:0006814; GO:0005890,potassium ion transport; sodium ion transport; sodium:potassium-exchanging ATPase complex,PF00287;,6.00E-85,CHOYP_MCM4.1.1,,,,,,,AT1B3_CAEBR,Caenorhabditis briggsae,potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] comp142987_c1_seq1,1969,38.1412,0.76992516,376,1776,,7.00E-24,Q92563,"Testican-2 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2)","Testican-2 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2)",GO:0005509; GO:0030198; GO:0005578; GO:0045595; GO:0007165; GO:0007416,calcium ion binding; extracellular matrix organization; proteinaceous extracellular matrix; regulation of cell differentiation; signal transduction; synapse assembly,PF07648;PF10591;PF00086;,,,2.00E-38,ruditapes2_c1326,,,,,TICN2_HUMAN,Homo sapiens (Human),extracellular matrix organization [GO:0030198]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of cell differentiation [GO:0045595]; signal transduction [GO:0007165]; synapse assembly [GO:0007416] comp142989_c0_seq1,2148,44.5531,0.44850876,26,76,,0,Q9R152,Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1),Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1),GO:0003677; GO:0051287; GO:0003950; GO:0006302; GO:0005730; GO:0006471; GO:0006355; GO:0006351; GO:0008270,"DNA binding; NAD binding; NAD+ ADP-ribosyltransferase activity; double-strand break repair; nucleolus; protein ADP-ribosylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;,1.00E-19,CHOYP_LOC100495846.1.1,,,,,,,PARP1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),"cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein ADP-ribosylation [GO:0006471]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142989_c0_seq2,3752,43.1237,0.44050976,16,87,,0,P09874,Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1),Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1),GO:0003677; GO:0042769; GO:0051287; GO:0003950; GO:0006284; GO:0032869; GO:0006302; GO:0000122; GO:0005635; GO:0005730; GO:0005654; GO:0016540; GO:0070212; GO:0040009; GO:0000723; GO:0005667; GO:0006367; GO:0007179; GO:0008270,"DNA binding; DNA damage response, detection of DNA damage; NAD binding; NAD+ ADP-ribosyltransferase activity; base-excision repair; cellular response to insulin stimulus; double-strand break repair; negative regulation of transcription from RNA polymerase II promoter; nuclear envelope; nucleolus; nucleoplasm; protein autoprocessing; protein poly-ADP-ribosylation; regulation of growth rate; telomere maintenance; transcription factor complex; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; zinc ion binding",PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;,0,CHOYP_LOC100533290.1.1,,,,,,,PARP1_HUMAN,Homo sapiens (Human),"cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; DNA damage response, detection of DNA damage [GO:0042769]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; lagging strand elongation [GO:0006273]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; protein sumoylation [GO:0016925]; regulation of cellular protein localization [GO:1903827]; signal transduction involved in regulation of gene expression [GO:0023019]; transcription from RNA polymerase II promoter [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp142989_c0_seq3,3790,43.0343,0.44344717,27,183,,0,Q9R152,Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1),Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1),GO:0003677; GO:0051287; GO:0003950; GO:0006302; GO:0005730; GO:0006471; GO:0006355; GO:0006351; GO:0008270,"DNA binding; NAD binding; NAD+ ADP-ribosyltransferase activity; double-strand break repair; nucleolus; protein ADP-ribosylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;,,,,,,,,,PARP1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),"cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein ADP-ribosylation [GO:0006471]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142989_c0_seq4,645,46.2016,0.45621579,5,0,,,,,,,,,3.00E-46,CHOYP_LOC100533290.1.1,,,,,,,,, comp142990_c0_seq1,4188,43.0516,0.60434663,0,17,,4.00E-79,Q32S26,Bromodomain-containing protein 2,Bromodomain-containing protein 2,GO:0003682; GO:0016568; GO:0070577; GO:0006334; GO:0005634; GO:0006357; GO:0006351,"chromatin binding; chromatin modification; histone acetyl-lysine binding; nucleosome assembly; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF17035;PF00439;,,,,,,,,,BRD2_BOVIN,Bos taurus (Bovine),"chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142990_c0_seq2,4158,43.1217,0.60143717,12,12,,5.00E-80,Q32S26,Bromodomain-containing protein 2,Bromodomain-containing protein 2,GO:0003682; GO:0016568; GO:0070577; GO:0006334; GO:0005634; GO:0006357; GO:0006351,"chromatin binding; chromatin modification; histone acetyl-lysine binding; nucleosome assembly; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF17035;PF00439;,4.00E-66,CHOYP_BRD4.1.1,,,,,,,BRD2_BOVIN,Bos taurus (Bovine),"chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142990_c0_seq3,6688,38.9803,0.5494646,8,0,,5.00E-22,Q9Y7N0,SWR1 complex bromodomain subunit bdf1,SWR1 complex bromodomain subunit bdf1,GO:0000812; GO:0016568; GO:0006355; GO:0006351,"Swr1 complex; chromatin modification; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF17035;PF00439;,,,,,,,,,BDF1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp142990_c0_seq4,5672,36.3011,0.61306476,0,0,,2.00E-46,Q58F21,Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein),Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein),GO:0008380; GO:0030154; GO:0006338; GO:0070577; GO:0001207; GO:0006397; GO:0007141; GO:0005634; GO:0051039; GO:0043484; GO:0007283; GO:0003713; GO:0006351,"RNA splicing; cell differentiation; chromatin remodeling; histone acetyl-lysine binding; histone displacement; mRNA processing; male meiosis I; nucleus; positive regulation of transcription during meiosis; regulation of RNA splicing; spermatogenesis; transcription coactivator activity; transcription, DNA-dependent",PF17035;PF17105;PF00439;,7.00E-65,CHOYP_BRD4.1.1,,,,,,,BRDT_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; chromatin remodeling [GO:0006338]; histone displacement [GO:0001207]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; mRNA processing [GO:0006397]; positive regulation of transcription involved in meiotic cell cycle [GO:0051039]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp142990_c0_seq5,1223,43.5814,0.45364382,26,13,,,,,,,,,,,8.00E-23,ruditapes_c23780,,,,,,, comp142990_c0_seq6,5642,36.3169,0.6155741,0,0,,3.00E-79,Q32S26,Bromodomain-containing protein 2,Bromodomain-containing protein 2,GO:0003682; GO:0016568; GO:0070577; GO:0006334; GO:0005634; GO:0006357; GO:0006351,"chromatin binding; chromatin modification; histone acetyl-lysine binding; nucleosome assembly; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF17035;PF00439;,7.00E-65,CHOYP_BRD4.1.1,,,,,,,BRD2_BOVIN,Bos taurus (Bovine),"chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142990_c0_seq7,6658,39.0357,0.55017358,0,12,,5.00E-79,Q32S26,Bromodomain-containing protein 2,Bromodomain-containing protein 2,GO:0003682; GO:0016568; GO:0070577; GO:0006334; GO:0005634; GO:0006357; GO:0006351,"chromatin binding; chromatin modification; histone acetyl-lysine binding; nucleosome assembly; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF17035;PF00439;,,,1.00E-99,ruditapes2_c1914,,,,,BRD2_BOVIN,Bos taurus (Bovine),"chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp142991_c0_seq2,2327,36.3128,0.57245683,165,110,,1.00E-35,Q6GLW1,THO complex subunit 4-B (Tho4-B) (Aly/REF export factor-B),THO complex subunit 4-B (Tho4-B) (Aly/REF export factor-B),GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0051028; GO:0016607; GO:0000166,RNA binding; RNA splicing; cytoplasm; mRNA processing; mRNA transport; nuclear speck; nucleotide binding,PF13865;PF00076;,,,,,,,,,THO4B_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; RNA splicing [GO:0008380] comp142991_c0_seq3,2355,36.3907,0.56356412,42,33,,6.00E-09,Q09330,mRNA export protein mlo3 (RNA-annealing protein mlo3),mRNA export protein mlo3 (RNA-annealing protein mlo3),GO:0003723; GO:0000166; GO:0016973; GO:0000346,RNA binding; nucleotide binding; poly(A)+ mRNA export from nucleus; transcription export complex,PF13865;PF00076;,5.00E-44,CHOYP_LOC100375551.1.2,,,,,,,MLO3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),poly(A)+ mRNA export from nucleus [GO:0016973] comp142995_c5_seq1,3867,42.436,0.54323087,99,329,,3.00E-164,P36048,Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10),Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10),GO:0005525; GO:0003924; GO:0046540; GO:0030623; GO:0005682; GO:0000244; GO:0000349; GO:0000388,GTP binding; GTPase activity; U4/U6 x U5 tri-snRNP complex; U5 snRNA binding; U5 snRNP; assembly of spliceosomal tri-snRNP; generation of catalytic spliceosome for first transesterification step; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11),PF00679;PF03764;PF16004;PF03144;,,,,,,,,,SN114_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"generation of catalytic spliceosome for first transesterification step [GO:0000349]; mature ribosome assembly [GO:0042256]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388]" comp142995_c5_seq2,3839,42.5632,0.54969151,25,136,,0,Q5F3X4,"116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain protein 2) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)","116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain protein 2) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)",GO:0005525; GO:0006184; GO:0003924; GO:0008380; GO:0006397; GO:0005681,GTP binding; GTP catabolic process; GTPase activity; RNA splicing; mRNA processing; spliceosomal complex,PF00679;PF14492;PF03764;PF16004;PF03144;,0,CHOYP_U5S1.1.1,,,,,,,U5S1_CHICK,Gallus gallus (Chicken),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp142997_c0_seq1,2940,34.3197,0.49192751,89,220,,2.00E-56,Q9N285,Mitochondrial carrier homolog 2,Mitochondrial carrier homolog 2,GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,,,,,,,,,MTCH2_BOVIN,Bos taurus (Bovine),positive regulation of apoptotic process [GO:0043065]; transport [GO:0006810] comp142997_c0_seq2,2233,32.3332,0.46650744,12,19,,2.00E-10,Q791V5,Mitochondrial carrier homolog 2,Mitochondrial carrier homolog 2,GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,,,,,,,,,MTCH2_MOUSE,Mus musculus (Mouse),hepatocyte apoptotic process [GO:0097284]; positive regulation of apoptotic process [GO:0043065]; protein localization to mitochondrion [GO:0070585]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108] comp142998_c1_seq1,2899,45.326,0.77383047,61,0,,4.00E-59,A1L1W9,Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,MOT10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ion transmembrane transport [GO:0034220] comp142998_c1_seq2,1253,47.4062,0.99569029,15,0,,,,,,,,,6.00E-39,CHOYP_BRAFLDRAFT_120361.1.1,,,,,,,,, comp143003_c0_seq4,1548,38.6951,0.52436171,0,6,,2.00E-27,Q75QI0,Craniofacial development protein 1 (Bucentaur),Craniofacial development protein 1 (Bucentaur),GO:0007275,multicellular organismal development,PF07572;,2.00E-21,CHOYP_HHEX.2.2,,,,,,,CFDP1_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275] comp143004_c0_seq3,3994,41.8878,0.51071403,1318,11877,,0,P53618,Coatomer subunit beta (Beta-coat protein) (Beta-COP),Coatomer subunit beta (Beta-coat protein) (Beta-COP),GO:0048205; GO:0030126; GO:0005829; GO:0005793; GO:0006891; GO:0006886; GO:0019048; GO:0005886; GO:0006890; GO:0005198,"COPI coating of Golgi vesicle; COPI vesicle coat; cytosol; endoplasmic reticulum-Golgi intermediate compartment; intra-Golgi vesicle-mediated transport; intracellular protein transport; modulation by virus of host morphology or physiology; plasma membrane; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",PF01602;PF07718;PF14806;,0,CHOYP_COPB.1.1,2.00E-106,ruditapes_c7248,,,,,COPB_HUMAN,Homo sapiens (Human),"ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]" comp143007_c0_seq3,2177,34.8645,0.36597361,84,51,,,,,,,,,,,2.00E-71,ruditapes_c31357,,,,,,, comp143010_c0_seq1,733,39.8363,0.97444589,6,102,,6.00E-06,P60827,Complement C1q tumor necrosis factor-related protein 8 (C1q/TNF-related protein 8) (CTRP8),Complement C1q tumor necrosis factor-related protein 8 (C1q/TNF-related protein 8) (CTRP8),GO:0005581,collagen,PF00386;PF01391;,,,,,,,,,C1QT8_HUMAN,Homo sapiens (Human), comp143010_c0_seq2,1115,38.565,0.94404032,12,141,,8.00E-08,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp143014_c1_seq1,2709,46.2901,0.35157835,309,2500,,2.00E-126,P20072,Annexin A7 (Annexin VII) (Annexin-7) (Synexin),Annexin A7 (Annexin VII) (Annexin-7) (Synexin),GO:0005509; GO:0005544; GO:0008283; GO:0006874; GO:0009992; GO:0042584; GO:0005829; GO:0005789; GO:0007599; GO:0005635; GO:0005886; GO:0008360; GO:0009651; GO:0035176,calcium ion binding; calcium-dependent phospholipid binding; cell proliferation; cellular calcium ion homeostasis; cellular water homeostasis; chromaffin granule membrane; cytosol; endoplasmic reticulum membrane; hemostasis; nuclear envelope; plasma membrane; regulation of cell shape; response to salt stress; social behavior,PF00191;,2.00E-61,CHOYP_ANXA7.1.4,,,,,,,ANXA7_BOVIN,Bos taurus (Bovine),autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176] comp143014_c2_seq1,1568,44.6429,0.8782973,31,53,,9.00E-152,Q8WPW2,Probable pyridoxine biosynthesis SNZERR (Ethylene response protein) (PDX1 homolog),Pyridoxal 5'-phosphate synthase subunit SNZERR (PLP synthase subunit SNZERR) (EC 4.3.3.6) (Ethylene response protein) (PDX1),GO:0003824; GO:0042823; GO:0008615,catalytic activity; pyridoxal phosphate biosynthetic process; pyridoxine biosynthetic process,PF01680;,1.00E-157,CHOYP_NEMVEDRAFT_V1G194582.2.2,4.00E-59,ruditapes_c26571,,,,,PDX1_SUBDO,Suberites domuncula (Sponge),pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819] comp143014_c2_seq2,1581,44.4655,0.86528574,23,29,,,,,,,,,1.00E-157,CHOYP_NEMVEDRAFT_V1G194582.2.2,,,,,,,,, comp143015_c1_seq1,3349,41.4153,0.54931199,2048,11457,,0,Q91W50,Cold shock domain-containing protein E1,Cold shock domain-containing protein E1,GO:0070937; GO:0003677; GO:0003723; GO:0005743; GO:0070966; GO:0006355,"CRD-mediated mRNA stability complex; DNA binding; RNA binding; mitochondrial inner membrane; nuclear-transcribed mRNA catabolic process, no-go decay; regulation of transcription, DNA-dependent",PF00313;PF12901;,6.00E-171,CHOYP_LOC100377755.1.1,,,,,,,CSDE1_MOUSE,Mus musculus (Mouse),"nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; regulation of transcription, DNA-templated [GO:0006355]" comp143015_c2_seq1,215,25.1163,0.60590371,18,72,,,,,,,,,5.00E-12,CHOYP_contig_032397,,,,,,,,, comp143017_c2_seq1,1584,37.9419,0.43845107,35,156,,7.00E-74,Q6DEW6,RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein),RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein),GO:0004527; GO:0003676; GO:0090305; GO:0005634,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF00929;,9.00E-45,CHOYP_REXO4.1.1,,,,,,,REXO4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143017_c2_seq2,1540,38.0519,0.43030078,66,147,,2.00E-73,Q9GZR2,RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog) (hPMC2),RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog) (hPMC2),GO:0004527; GO:0003676; GO:0090305; GO:0005730; GO:0003700,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleolus; sequence-specific DNA binding transcription factor activity,PF00929;,2.00E-46,CHOYP_REXO4.1.1,,,,,,,REXO4_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]" comp143018_c1_seq1,536,48.8806,0.79133786,19,51,,5.00E-22,P76440,NAD-dependent dihydropyrimidine dehydrogenase subunit PreT (DPD) (EC 1.3.1.1) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase),NAD-dependent dihydropyrimidine dehydrogenase subunit PreT (DPD) (EC 1.3.1.1) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase),GO:0003954; GO:0004159; GO:0050660; GO:0051536; GO:0006208,NADH dehydrogenase activity; dihydrouracil dehydrogenase (NAD+) activity; flavin adenine dinucleotide binding; iron-sulfur cluster binding; pyrimidine nucleobase catabolic process,PF14691;PF07992;,,,,,,,,,PRET_ECOLI,Escherichia coli (strain K12),pyrimidine nucleobase catabolic process [GO:0006208] comp143018_c3_seq3,4532,40.6884,0.93993793,137,1619,,0,O89000,Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase),Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase),GO:0051539; GO:0050661; GO:0006222; GO:0019483; GO:0007623; GO:0005829; GO:0004158; GO:0017113; GO:0046872; GO:0042803; GO:0042493; GO:0051384; GO:0007584; GO:0006214; GO:0002058; GO:0006212,"4 iron, 4 sulfur cluster binding; NADP binding; UMP biosynthetic process; beta-alanine biosynthetic process; circadian rhythm; cytosol; dihydroorotate oxidase activity; dihydropyrimidine dehydrogenase (NADP+) activity; metal ion binding; protein homodimerization activity; response to drug; response to glucocorticoid stimulus; response to nutrient; thymidine catabolic process; uracil binding; uracil catabolic process",PF01180;PF14691;PF07992;,0,CHOYP_BRAFLDRAFT_129513.1.1,5.00E-114,ruditapes_c18807,,,,,DPYD_RAT,Rattus norvegicus (Rat),beta-alanine biosynthetic process [GO:0019483]; circadian rhythm [GO:0007623]; pyrimidine nucleobase catabolic process [GO:0006208]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584]; thymidine catabolic process [GO:0006214]; uracil catabolic process [GO:0006212]; uracil metabolic process [GO:0019860] comp143020_c0_seq1,3357,42.3295,0.63823349,3108,11261,,0,Q7ZY18,Zygotic DNA replication licensing factor mcm6-B (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b),Zygotic DNA replication licensing factor mcm6-B (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006270; GO:0042555; GO:0007049; GO:0046872; GO:0005634; GO:0030174,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication initiation; MCM complex; cell cycle; metal ion binding; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF14551;,0,CHOYP_BRAFLDRAFT_123986.1.1,,,,,,,MC6ZB_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp143022_c0_seq1,2120,34.8585,0.5748474,49,9,,4.00E-47,Q6NZQ0,Coiled-coil domain-containing protein C16orf93 homolog,Coiled-coil domain-containing protein 189,,,PF14769;,,,,,,,,,CP093_MOUSE,Mus musculus (Mouse), comp143022_c0_seq2,2289,33.8576,0.61005673,58,9,,,,,,,,,5.00E-107,CHOYP_LOC100376096.1.1,,,,,,,,, comp143022_c0_seq8,2085,34.6763,0.52692909,17,43,,4.00E-47,Q6NZQ0,Coiled-coil domain-containing protein C16orf93 homolog,Coiled-coil domain-containing protein 189,,,PF14769;,4.00E-107,CHOYP_LOC100376096.1.1,8.00E-95,ruditapes_c25464,1.00E-94,AM864669.p.cg.6,5,,CP093_MOUSE,Mus musculus (Mouse), comp143023_c0_seq1,2481,40.7094,0.60369404,555,2152,,5.00E-19,Q5EAW9,Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3),Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3),GO:0005634; GO:0006355; GO:0006351; GO:0008270,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;,1.00E-39,CHOYP_LOC100372715.1.1,,,,,,,TAF3_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143024_c0_seq1,1941,34.3122,1.05421279,54,580,,2.00E-08,P74148,Universal stress protein Sll1388 (USP Sll1388),Universal stress protein Sll1388 (USP Sll1388),GO:0006950,response to stress,PF00582;,1.00E-12,CHOYP_LOC587133.1.1,3.00E-18,ruditapes2_c174,,,,,Y1388_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),response to stress [GO:0006950] comp143025_c1_seq1,2827,47.2232,0.57967193,268,226,,0,Q90705,Elongation factor 2 (EF-2),Elongation factor 2 (EF-2),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,6.00E-88,CHOYP_EEF2.2.2,1.00E-137,ruditapes_c1495,,,,,EF2_CHICK,Gallus gallus (Chicken),translation [GO:0006412] comp143025_c1_seq2,1708,47.8923,0.57384025,12,12,,1.00E-40,A6UV44,Elongation factor 2 (EF-2),Elongation factor 2 (EF-2),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,2.00E-84,CHOYP_EF2.3.5,,,,,,,EF2_META3,Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3), comp143027_c0_seq1,3147,42.3896,0.50814832,4149,38,male>female,0,Q9WV04,Kinesin-like protein KIF9,Kinesin-like protein KIF9,GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytosol; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,0,CHOYP_LOC100370673.1.1,,,,,,,KIF9_MOUSE,Mus musculus (Mouse),extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of podosome assembly [GO:0071801] comp143028_c0_seq1,2190,30.5023,0.31858961,1887,566,,2.00E-07,Q9D9T0,DPY30 domain-containing protein 1,DPY30 domain-containing protein 1,,,PF05186;,1.00E-13,CHOYP_BRAFLDRAFT_120058.1.1,,,,,,,DYDC1_MOUSE,Mus musculus (Mouse),chromatin silencing at telomere [GO:0006348]; histone H3-K4 methylation [GO:0051568] comp143031_c0_seq1,3781,40.4126,0.50403367,0,0,,2.00E-43,Q7Z478,ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx),ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx),GO:0005524; GO:0008026; GO:0016282; GO:0005739; GO:0043024; GO:0003743,ATP binding; ATP-dependent helicase activity; eukaryotic 43S preinitiation complex; mitochondrion; ribosomal small subunit binding; translation initiation factor activity,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_DHX15.2.2,,,,,,,DHX29_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp143031_c0_seq10,1550,39.871,0.59035137,0,0,,,,,,,,,1.00E-48,CHOYP_LOC654855.1.1,,,,,,,,, comp143031_c0_seq11,4036,39.4945,0.4999143,3,30,,0,Q5RAZ4,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),GO:0005524; GO:0008026; GO:0008380; GO:0006397; GO:0003676; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA splicing; mRNA processing; nucleic acid binding; nucleolus,PF00270;PF04408;PF00271;PF07717;,2.00E-32,CHOYP_LOC100375367.1.1,,,,,,,DHX15_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp143031_c0_seq2,4148,39.1514,0.49408847,0,0,,0,O35286,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),GO:0005524; GO:0008026; GO:0008380; GO:0005689; GO:0003725; GO:0006397; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA splicing; U12-type spliceosomal complex; double-stranded RNA binding; mRNA processing; nucleolus,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX15_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]" comp143031_c0_seq3,3749,40.2507,0.53232078,235,116,,0,O35286,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),GO:0005524; GO:0008026; GO:0008380; GO:0005689; GO:0003725; GO:0006397; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA splicing; U12-type spliceosomal complex; double-stranded RNA binding; mRNA processing; nucleolus,PF00270;PF04408;PF00271;PF07717;,,,,,,,,,DHX15_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]" comp143031_c0_seq4,3715,40.2692,0.50988758,374,112,,0,O43143,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15),Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15),GO:0005524; GO:0008026; GO:0003724; GO:0008380; GO:0005689; GO:0006397; GO:0003676; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA helicase activity; RNA splicing; U12-type spliceosomal complex; mRNA processing; nucleic acid binding; nucleolus,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_DHX15.2.2,,,,,,,DHX15_HUMAN,Homo sapiens (Human),"mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]; RNA splicing [GO:0008380]" comp143031_c0_seq5,4215,39.2883,0.48910952,8,51,,2.00E-41,Q5R874,ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),GO:0005524; GO:0008026; GO:0070937; GO:0070934; GO:0003677; GO:0003723; GO:0005813; GO:0005730; GO:0030529,ATP binding; ATP-dependent helicase activity; CRD-mediated mRNA stability complex; CRD-mediated mRNA stabilization; DNA binding; RNA binding; centrosome; nucleolus; ribonucleoprotein complex,PF00270;PF00035;PF04408;PF00271;PF07717;,4.00E-48,CHOYP_LOC654855.1.1,,,,,,,DHX9_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),CRD-mediated mRNA stabilization [GO:0070934]; osteoblast differentiation [GO:0001649]; rhythmic process [GO:0048511] comp143031_c0_seq6,3816,40.304,0.51535244,0,0,,2.00E-43,Q7Z478,ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx),ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx),GO:0005524; GO:0008026; GO:0016282; GO:0005739; GO:0043024; GO:0003743,ATP binding; ATP-dependent helicase activity; eukaryotic 43S preinitiation complex; mitochondrion; ribosomal small subunit binding; translation initiation factor activity,PF00270;PF04408;PF00271;PF07717;,3.00E-24,CHOYP_PRP16.1.1,,,,,,,DHX29_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp143031_c0_seq7,4183,39.0868,0.50428628,3,18,,0,O35286,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15),GO:0005524; GO:0008026; GO:0008380; GO:0005689; GO:0003725; GO:0006397; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA splicing; U12-type spliceosomal complex; double-stranded RNA binding; mRNA processing; nucleolus,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_DHX15.2.2,,,,,,,DHX15_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]" comp143031_c0_seq8,1585,39.6845,0.61549484,0,0,,,,,,,,,6.00E-129,CHOYP_DHX15.2.2,,,,,,,,, comp143032_c2_seq1,1172,38.3959,0.51513132,44,320,,4.00E-08,Q9D9K3,Cell death regulator Aven,Cell death regulator Aven,GO:0006915; GO:0012505; GO:0005622; GO:0016020; GO:0043066,apoptotic process; endomembrane system; intracellular; membrane; negative regulation of apoptotic process,,,,,,,,,,AVEN_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066] comp143035_c0_seq1,1685,42.5519,0.35535757,336,270,,0,A0AVF1,Tetratricopeptide repeat protein 26 (TPR repeat protein 26),Intraflagellar transport protein 56 (Tetratricopeptide repeat protein 26) (TPR repeat protein 26),GO:0042384; GO:0036064; GO:0072372,cilium assembly; cilium basal body; primary cilium,,0,CHOYP_BRAFLDRAFT_60331.1.1,,,,,,,TTC26_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; smoothened signaling pathway [GO:0007224]; spermatid development [GO:0007286] comp143040_c0_seq1,1823,41.141,0.73696992,467,350,,5.00E-64,P62287,Abnormal spindle-like microcephaly-associated protein homolog,Abnormal spindle-like microcephaly-associated protein homolog,GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,5.00E-42,CHOYP_LOC101174988.1.1,,,,,,,ASPM_COLGU,Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp143041_c0_seq1,3263,44.8054,0.55587501,9,0,,0,O60494,Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0009235; GO:0015889; GO:0005829; GO:0030139; GO:0005783; GO:0010008; GO:0031232; GO:0042157; GO:0042953; GO:0043202; GO:0005765; GO:0042803; GO:0004872; GO:0006898; GO:0001894; GO:0005215; GO:0042359,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; cobalamin metabolic process; cobalamin transport; cytosol; endocytic vesicle; endoplasmic reticulum; endosome membrane; extrinsic to external side of plasma membrane; lipoprotein metabolic process; lipoprotein transport; lysosomal lumen; lysosomal membrane; protein homodimerization activity; receptor activity; receptor-mediated endocytosis; tissue homeostasis; transporter activity; vitamin D metabolic process,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_HUMAN,Homo sapiens (Human),cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359] comp143041_c0_seq2,2337,44.0736,0.53782403,6,0,,7.00E-49,P25723,Dorsal-ventral patterning protein tolloid (EC 3.4.24.-),Dorsal-ventral patterning protein tolloid (EC 3.4.24.-),GO:0007378; GO:0005509; GO:0005576; GO:0008586; GO:0007313; GO:0004222; GO:0010629; GO:0030513; GO:0016485; GO:0006508; GO:0017015; GO:0007362; GO:0008293; GO:0008270,"amnioserosa formation; calcium ion binding; extracellular region; imaginal disc-derived wing vein morphogenesis; maternal specification of dorsal/ventral axis, oocyte, soma encoded; metalloendopeptidase activity; negative regulation of gene expression; positive regulation of BMP signaling pathway; protein processing; proteolysis; regulation of transforming growth factor beta receptor signaling pathway; terminal region determination; torso signaling pathway; zinc ion binding",PF01400;PF00431;PF07645;,,,,,,,,,TLD_DROME,Drosophila melanogaster (Fruit fly),"amnioserosa formation [GO:0007378]; embryonic pattern specification [GO:0009880]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; negative regulation of gene expression [GO:0010629]; positive regulation of BMP signaling pathway [GO:0030513]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; zygotic specification of dorsal/ventral axis [GO:0007352]" comp143041_c0_seq4,1908,45.3354,0.57150815,0,0,,1.00E-67,Q60997,Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80),Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80),GO:0030154; GO:0019898; GO:0001833; GO:0016021; GO:0030858; GO:0015031; GO:0005578; GO:0005044; GO:0030658; GO:0035375; GO:0042589,cell differentiation; extrinsic to membrane; inner cell mass cell proliferation; integral to membrane; positive regulation of epithelial cell differentiation; protein transport; proteinaceous extracellular matrix; scavenger receptor activity; transport vesicle membrane; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,,,,,,,,,DMBT1_MOUSE,Mus musculus (Mouse),blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031] comp143041_c0_seq5,1421,45.9536,0.54759114,0,0,,1.00E-83,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,6.00E-34,CHOYP_LOC591417.2.2,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp143041_c0_seq6,802,38.7781,0.43207849,5,0,,3.00E-16,P42662,Astacin-like metalloendopeptidase (EC 3.4.24.-),Astacin-like metalloendopeptidase (EC 3.4.24.-),GO:0070001; GO:0007155; GO:0060473; GO:0070002; GO:0004222; GO:2000360; GO:0005886; GO:0010954; GO:0060468; GO:0006508; GO:0030133; GO:0008270,aspartic-type peptidase activity; cell adhesion; cortical granule; glutamic-type peptidase activity; metalloendopeptidase activity; negative regulation of binding of sperm to zona pellucida; plasma membrane; positive regulation of protein processing; prevention of polyspermy; proteolysis; transport vesicle; zinc ion binding,PF01400;PF00431;,,,,,,,,,ASTL_COTJA,Coturnix coturnix japonica (Japanese quail) (Coturnix japonica),cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468] comp143041_c0_seq7,982,44.2974,0.54205783,0,0,,6.00E-48,O43897,Tolloid-like protein 1 (EC 3.4.24.-),Tolloid-like protein 1 (EC 3.4.24.-),GO:0005509; GO:0030154; GO:0030198; GO:0005576; GO:0004222; GO:0006508; GO:0001501; GO:0008270,calcium ion binding; cell differentiation; extracellular matrix organization; extracellular region; metalloendopeptidase activity; proteolysis; skeletal system development; zinc ion binding,PF01400;PF00431;PF07645;,,,,,,,,,TLL1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; skeletal system development [GO:0001501] comp143042_c0_seq1,1810,33.8122,0.28050503,892,43,,9.00E-55,Q4R8V8,Coiled-coil domain-containing protein 37,Cilia- and flagella-associated protein 100 (Coiled-coil domain-containing protein 37),,,PF13863;,2.00E-142,CHOYP_LOC100370537.1.1,,,,,,,CCD37_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143042_c1_seq1,513,38.0117,0.502828,8,19,,,,,,,,,,,7.00E-51,ruditapes_c6173,,,,,,, comp143045_c0_seq1,3124,41.1652,0.33334306,65,150,,3.00E-39,Q6DF94,Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52),Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52),GO:0051301; GO:0005814; GO:0007067; GO:0046599; GO:0005819,cell division; centriole; mitosis; regulation of centriole replication; spindle,PF15678;,,,,,,,,,SPICE_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic spindle assembly [GO:0090307]; regulation of centriole replication [GO:0046599] comp143045_c0_seq2,3140,41.0828,0.33302092,164,303,,3.00E-38,Q2T9X8,Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52),Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52),GO:0051301; GO:0005814; GO:0046599; GO:0005819; GO:0090307,cell division; centriole; regulation of centriole replication; spindle; spindle assembly involved in mitosis,PF15678;,1.00E-28,CHOYP_BRAFLDRAFT_129034.1.1,,,,,,,SPICE_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; metaphase plate congression [GO:0051310]; mitotic spindle assembly [GO:0090307]; regulation of centriole replication [GO:0046599] comp143047_c1_seq1,4566,42.0718,0.50476903,589,568,,0,Q8CCP0,Nuclear export mediator factor Nemf (Serologically defined colon cancer antigen 1 homolog),Nuclear export mediator factor Nemf (Serologically defined colon cancer antigen 1 homolog),GO:0005737; GO:0051168; GO:0005634,cytoplasm; nuclear export; nucleus,PF11923;PF05670;,0,CHOYP_NEMF.1.1,5.00E-26,ruditapes_c8194,,,,,NEMF_MOUSE,Mus musculus (Mouse),nuclear export [GO:0051168] comp143049_c0_seq1,1526,40.4325,0.57349368,257,1835,,3.00E-62,Q3T042,RNA-binding protein NOB1,RNA-binding protein NOB1,GO:0046872; GO:0005634,metal ion binding; nucleus,PF08772;PF17146;PF15017;,9.00E-51,CHOYP_LOC575793.2.2,1.00E-52,ruditapes_c29963,,,,,NOB1_BOVIN,Bos taurus (Bovine),cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA [GO:0030490] comp143049_c1_seq1,3438,41.7394,0.3716348,3,82,,,,,,,,,7.00E-158,CHOYP_APC1.3.3,,,,,,,,, comp143049_c1_seq2,2667,42.2197,0.33143495,3,0,,3.00E-95,Q54NC6,Anaphase-promoting complex subunit 1 (APC1),Anaphase-promoting complex subunit 1 (APC1),GO:0005680; GO:0031145; GO:0051301; GO:0007067; GO:0016567,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; mitosis; protein ubiquitination,,,,,,,,,,APC1_DICDI,Dictyostelium discoideum (Slime mold),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp143049_c1_seq3,4217,42.3524,0.37288591,65,198,,0,Q9H1A4,Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),GO:0005680; GO:0031145; GO:0051301; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination,PF12859;,0,CHOYP_APC1.3.3,,,,,,,APC1_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp143050_c0_seq1,2086,36.1937,1.14232609,218,944,,3.00E-43,Q9PWD2,Homeobox protein Hox-A4,Homeobox protein Hox-A4,GO:0007275; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;,2.00E-34,CHOYP_HXD4A.1.1,,,,,,,HXA4_MORSA,Morone saxatilis (Striped bass) (Perca saxatilis),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp143052_c0_seq1,3191,39.016,0.40965311,35,158,,3.00E-179,Q8NI60,"Chaperone activity of bc1 complex-like, mitochondrial (Chaperone-ABC1-like) (EC 2.7.11.-) (aarF domain-containing protein kinase 3)","Atypical kinase ADCK3, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (aarF domain-containing protein kinase 3)",GO:0005524; GO:0008219; GO:0005739; GO:0004674,ATP binding; cell death; mitochondrion; protein serine/threonine kinase activity,PF03109;,2.00E-93,CHOYP_LOC100693708.1.1,,,,,,,ADCK3_HUMAN,Homo sapiens (Human),phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744] comp143052_c0_seq2,3202,39.0693,0.4072336,17,164,,2.00E-122,Q29RI0,"Chaperone activity of bc1 complex-like, mitochondrial (Chaperone-ABC1-like) (EC 2.7.11.-) (aarF domain-containing protein kinase 3)","Atypical kinase ADCK3, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (aarF domain-containing protein kinase 3)",GO:0005524; GO:0005739; GO:0004674,ATP binding; mitochondrion; protein serine/threonine kinase activity,PF03109;,,,,,,,,,ADCK3_BOVIN,Bos taurus (Bovine),phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744] comp143053_c0_seq1,2616,42.393,0.43800751,116,166,,0,O35218,Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit),Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit),GO:0003723; GO:0006398; GO:0016787; GO:0006379; GO:0005847; GO:0006378,RNA binding; histone mRNA 3'-end processing; hydrolase activity; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation,PF10996;PF13299;PF16661;PF07521;,0,CHOYP_CPSF2.1.1,,,,,,,CPSF2_MOUSE,Mus musculus (Mouse),mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp143055_c2_seq1,3017,41.6971,0.54800181,238,940,,3.00E-72,Q97VS5,Phosphoenolpyruvate carboxykinase [GTP] (PEP carboxykinase) (PEPCK) (EC 4.1.1.32) (Phosphoenolpyruvate carboxylase),Phosphoenolpyruvate carboxykinase [GTP] (PEP carboxykinase) (PEPCK) (EC 4.1.1.32),GO:0005525; GO:0005737; GO:0006094; GO:0030145; GO:0004613,GTP binding; cytoplasm; gluconeogenesis; manganese ion binding; phosphoenolpyruvate carboxykinase (GTP) activity,PF00821;,0,CHOYP_PCKG.1.2,2.00E-28,ruditapes_c19567,,,,,PCKG_SULSO,Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2),gluconeogenesis [GO:0006094] comp143055_c2_seq2,3045,41.445,0.54954432,325,1144,,0,Q16822,"Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) (Phosphoenolpyruvate carboxylase)","Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32)",GO:0005525; GO:0006094; GO:0046872; GO:0005759; GO:0004613; GO:0004611; GO:0044281,GTP binding; gluconeogenesis; metal ion binding; mitochondrial matrix; phosphoenolpyruvate carboxykinase (GTP) activity; phosphoenolpyruvate carboxykinase activity; small molecule metabolic process,PF00821;,0,CHOYP_PCKG.1.2,1.00E-24,ruditapes_c15747,,,,,PCKGM_HUMAN,Homo sapiens (Human),gluconeogenesis [GO:0006094] comp143056_c0_seq1,2861,46.1377,1.07782019,4310,3,male>female,6.00E-62,Q8C1R0,Testis-specific serine/threonine-protein kinase 5 (TSK-5) (TSSK-5) (Testis-specific kinase 5) (EC 2.7.11.1),Testis-specific serine/threonine-protein kinase 5 (TSK-5) (TSSK-5) (Testis-specific kinase 5) (EC 2.7.11.1),GO:0005524; GO:0030154; GO:0000287; GO:0007275; GO:0004674; GO:0007283,ATP binding; cell differentiation; magnesium ion binding; multicellular organismal development; protein serine/threonine kinase activity; spermatogenesis,PF00069;,8.00E-36,CHOYP_LOC100378333.1.1,,,,,,,TSSK5_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] comp143057_c0_seq2,2175,38.8506,0.53636905,1,715,female>male,3.00E-33,P0C242,Cyclin-O,Cyclin-O,GO:0006284; GO:0007049; GO:0051301; GO:0005654; GO:0000079; GO:0004844,base-excision repair; cell cycle; cell division; nucleoplasm; regulation of cyclin-dependent protein serine/threonine kinase activity; uracil DNA N-glycosylase activity,PF02984;PF00134;,,,,,,,,,CCNO_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0042384]; multi-ciliated epithelial cell differentiation [GO:1903251]; response to drug [GO:0042493] comp143057_c0_seq4,936,40.2778,0.44830064,0,130,,2.00E-14,P24868,G2/mitotic-specific cyclin-1,G2/mitotic-specific cyclin-1,GO:0000086; GO:0051301; GO:0000307; GO:0016538; GO:0005737; GO:0008315; GO:0007067; GO:0030472; GO:0005634; GO:0010696; GO:0000079,G2/M transition of mitotic cell cycle; cell division; cyclin-dependent protein kinase holoenzyme complex; cyclin-dependent protein serine/threonine kinase regulator activity; cytoplasm; meiotic G2/MI transition; mitosis; mitotic spindle organization in nucleus; nucleus; positive regulation of spindle pole body separation; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,,,,,,,,,CG21_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic G2/MI transition [GO:0008315]; mitotic nuclear division [GO:0007067]; mitotic spindle organization in nucleus [GO:0030472]; positive regulation of spindle pole body separation [GO:0010696]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] comp143058_c0_seq1,2947,38.378,0.42669524,126,1615,,0,Q7SY23,"Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)","Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)",GO:0003842; GO:0005759; GO:0016620; GO:0006561; GO:0010133,"1-pyrroline-5-carboxylate dehydrogenase activity; mitochondrial matrix; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; proline biosynthetic process; proline catabolic process to glutamate",PF00171;,3.00E-123,CHOYP_AL4A1.1.1,,,,,,,AL4A1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glutamate biosynthetic process [GO:0006537]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133] comp143060_c0_seq2,2849,42.3306,0.58069115,14,0,,0,Q4R628,Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A),Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A),GO:0005524; GO:0042384; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0072372,ATP binding; cilium assembly; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; primary cilium,PF00225;,0,CHOYP_KIF3A.1.1,,,,,,,KIF3A_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018] comp143060_c0_seq3,2816,42.4716,0.59925468,32,24,,0,P46872,Kinesin-II 85 kDa subunit (KRP-85/95 85 kDa subunit),Kinesin-II 85 kDa subunit (KRP-85/95 85 kDa subunit),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,7.00E-68,CHOYP_LOC100377381.2.2,,,,,,,KRP85_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),microtubule-based movement [GO:0007018] comp143060_c0_seq4,1638,40.4762,0.55719636,0,0,,1.00E-92,Q4R628,Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A),Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A),GO:0005524; GO:0042384; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0072372,ATP binding; cilium assembly; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; primary cilium,PF00225;,,,,,,,,,KIF3A_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018] comp143060_c0_seq5,574,42.6829,0.74695974,2,0,,2.00E-62,P46871,Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit),Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,,,,,,,,,KRP95_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018] comp143061_c3_seq1,1820,40.2747,0.72571644,4,45,,2.00E-124,O88941,Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glycoprotein-processing glucosidase I),Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glycoprotein-processing glucosidase I),GO:0005789; GO:0016021; GO:0004573; GO:0009311,endoplasmic reticulum membrane; integral to membrane; mannosyl-oligosaccharide glucosidase activity; oligosaccharide metabolic process,PF03200;PF16923;,,,,,,,,,MOGS_RAT,Rattus norvegicus (Rat),oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487] comp143061_c3_seq5,441,38.5488,0.26061455,8,30,,,,,,,,,1.00E-43,CHOYP_BRAFLDRAFT_247063.1.1,,,,,,,,, comp143063_c1_seq1,662,44.5619,0.64002169,0,0,,3.00E-08,Q6Z9R8,Putative heat stress transcription factor B-4a (Heat stress transcription factor 20) (OsHsf-20),Putative heat stress transcription factor B-4a (Heat stress transcription factor 20) (OsHsf-20),GO:0005634; GO:0009408; GO:0043565; GO:0003700; GO:0006351,"nucleus; response to heat; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00447;,,,,,,,,,HFB4A_ORYSJ,Oryza sativa subsp. japonica (Rice),"transcription, DNA-templated [GO:0006351]" comp143063_c1_seq5,881,43.1328,0.75741808,43,0,,5.00E-16,Q9UBD0,"Heat shock transcription factor, X-linked","Heat shock transcription factor, X-linked",GO:0005737; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"cytoplasm; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00447;,,,,,,,,,HSFX1_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp143064_c0_seq3,6066,38.6911,0.36129042,84,143,,5.00E-103,Q8VCD7,Lysine-specific demethylase 4C (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C),Lysine-specific demethylase 4C (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C),GO:0051213; GO:0032454; GO:0000790; GO:0008284; GO:0006357; GO:0006351; GO:0008270,"dioxygenase activity; histone demethylase activity (H3-K9 specific); nuclear chromatin; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; zinc ion binding",PF02373;PF02375;,,,,,,,,,KDM4C_MOUSE,Mus musculus (Mouse),"blastocyst formation [GO:0001825]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of cell proliferation [GO:0008284]; regulation of gene expression [GO:0010468]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143064_c0_seq4,5411,39.3643,0.34358755,0,0,,2.00E-23,P55201,Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140),Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140),GO:0003677; GO:0070776; GO:0005737; GO:0043966; GO:0005886; GO:0045893; GO:0006351; GO:0008270,"DNA binding; MOZ/MORF histone acetyltransferase complex; cytoplasm; histone H3 acetylation; plasma membrane; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF10513;PF00855;,2.00E-22,CHOYP_KDM4C.1.1,,,,,,,BRPF1_HUMAN,Homo sapiens (Human),"histone H3 acetylation [GO:0043966]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp143064_c0_seq6,1436,40.8774,0.47402299,82,113,,0,Q9V6L0,Probable lysine-specific demethylase 4B (EC 1.14.11.-) (Probable JmjC domain-containing histone demethylation protein 3B),Probable lysine-specific demethylase 4B (EC 1.14.11.-) (Probable JmjC domain-containing histone demethylation protein 3B),GO:0051864; GO:0032454; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific); metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF02373;PF02375;,0,CHOYP_KDM4C.1.1,,,,,,,KDM4B_DROME,Drosophila melanogaster (Fruit fly),"histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp143065_c0_seq4,900,44.1111,0.39111942,226,841,,3.00E-26,A4IIZ9,Mediator of RNA polymerase II transcription subunit 28 (Mediator complex subunit 28),Mediator of RNA polymerase II transcription subunit 28 (Mediator complex subunit 28),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11594;,,,2.00E-17,ruditapes_c24477,,,,,MED28_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143067_c0_seq1,1057,37.843,0.76774165,67,331,,7.00E-06,P41047,"Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]","Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]",GO:0070231; GO:0006919; GO:0060555; GO:0060554; GO:0005901; GO:0030644; GO:0033554; GO:0060205; GO:0048388; GO:0009897; GO:0005615; GO:0070062; GO:0008625; GO:0006955; GO:0006925; GO:0016021; GO:0043202; GO:0070265; GO:0016525; GO:0000122; GO:0005634; GO:0048471; GO:0043123; GO:0043065; GO:0008284; GO:2000353; GO:0045742; GO:0043525; GO:0070848; GO:0032496; GO:0046666; GO:0006351,"T cell apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of necroptosis by extracellular signals; activation of necroptosis of activated-T cells; caveola; cellular chloride ion homeostasis; cellular response to stress; cytoplasmic membrane-bounded vesicle lumen; endosomal lumen acidification; external side of plasma membrane; extracellular space; extracellular vesicular exosome; extrinsic apoptotic signaling pathway via death domain receptors; immune response; inflammatory cell apoptotic process; integral to membrane; lysosomal lumen; necrotic cell death; negative regulation of angiogenesis; negative regulation of transcription from RNA polymerase II promoter; nucleus; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of endothelial cell apoptotic process; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of neuron apoptotic process; response to growth factor stimulus; response to lipopolysaccharide; retinal cell programmed cell death; transcription, DNA-dependent",PF00229;,,,,,,,,,TNFL6_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular chloride ion homeostasis [GO:0030644]; endosomal lumen acidification [GO:0048388]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; immune response [GO:0006955]; inflammatory cell apoptotic process [GO:0006925]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron apoptotic process [GO:0043525]; response to growth factor [GO:0070848]; response to lipopolysaccharide [GO:0032496]; retinal cell programmed cell death [GO:0046666]; T cell apoptotic process [GO:0070231]; transcription, DNA-templated [GO:0006351]" comp143068_c0_seq1,2104,44.6293,0.46834597,268,117,,0,Q9P2H3,Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56),Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56),GO:0060349; GO:0005813; GO:0035085; GO:0060271; GO:0005932; GO:0001649; GO:0007224,bone morphogenesis; centrosome; cilium axoneme; cilium morphogenesis; microtubule basal body; osteoblast differentiation; smoothened signaling pathway,,0,CHOYP_BRAFLDRAFT_275667.1.1,,,,,,,IFT80_HUMAN,Homo sapiens (Human),bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0042384]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; nonmotile primary cilium assembly [GO:0035058]; osteoblast differentiation [GO:0001649]; positive regulation of smoothened signaling pathway [GO:0045880]; smoothened signaling pathway [GO:0007224] comp143068_c0_seq2,779,42.2336,0.49936062,98,39,,6.00E-37,Q8K057,Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56),Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56),GO:0060349; GO:0005813; GO:0002062; GO:0042384; GO:0035085; GO:0036064; GO:2000051; GO:0001649; GO:0045880; GO:0007224,bone morphogenesis; centrosome; chondrocyte differentiation; cilium assembly; cilium axoneme; cilium basal body; negative regulation of non-canonical Wnt receptor signaling pathway; osteoblast differentiation; positive regulation of smoothened signaling pathway; smoothened signaling pathway,,,,,,,,,,IFT80_MOUSE,Mus musculus (Mouse),bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; intraciliary transport [GO:0042073]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; nonmotile primary cilium assembly [GO:0035058]; osteoblast differentiation [GO:0001649]; positive regulation of smoothened signaling pathway [GO:0045880]; smoothened signaling pathway [GO:0007224] comp143069_c2_seq1,2125,38.2118,0.34996557,140,780,,3.00E-57,Q9VY86,TM2 domain-containing protein CG11103,TM2 domain-containing protein CG11103,GO:0016021,integral to membrane,PF05154;,2.00E-47,CHOYP_ISCW_ISCW014721.1.1,,,,,,,TM2D2_DROME,Drosophila melanogaster (Fruit fly), comp143071_c0_seq1,1815,46.1157,0.5927302,31,17,,1.00E-107,Q640I9,Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B),Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B),GO:0003677; GO:0070544; GO:0051864; GO:0005730; GO:0019843; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); nucleolus; rRNA binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00646;PF02373;PF16866;PF02008;,,,,,,,,,KDM2B_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143071_c0_seq2,2098,40.3241,0.69689499,8,22,,1.00E-48,Q6PB97,F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19),F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19),GO:0003677; GO:0008270,DNA binding; zinc ion binding,PF00646;PF16866;PF02008;,,,,,,,,,FXL19_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp143071_c0_seq4,1800,46.1667,0.58562322,24,0,,1.00E-92,Q9Y2K7,Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),GO:0070544; GO:0051864; GO:0000790; GO:0005654; GO:0006355; GO:0006351; GO:0045322; GO:0008270,"histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); nuclear chromatin; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent; unmethylated CpG binding; zinc ion binding",PF00646;PF02373;PF16866;PF02008;,1.00E-68,CHOYP_KDM2B.1.1,,,,,,,KDM2A_HUMAN,Homo sapiens (Human),"double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143071_c0_seq5,2153,40.3623,0.70120196,12,16,,4.00E-06,Q9UF56,F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13),F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13),,,PF12937;PF13516;,,,,,,,,,FXL17_HUMAN,Homo sapiens (Human), comp143071_c0_seq8,1542,39.2348,0.71548785,49,57,,5.00E-57,Q8NHM5,Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B),Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B),GO:0003677; GO:0048596; GO:0021592; GO:0035518; GO:0070544; GO:0032452; GO:0051864; GO:0021993; GO:0021670; GO:0030901; GO:0021555; GO:2000178; GO:0043524; GO:0000122; GO:0005730; GO:0005634; GO:0019843; GO:0007283; GO:0021678; GO:0006351; GO:0008270,"DNA binding; embryonic camera-type eye morphogenesis; fourth ventricle development; histone H2A monoubiquitination; histone H3-K36 demethylation; histone demethylase activity; histone demethylase activity (H3-K36 specific); initiation of neural tube closure; lateral ventricle development; midbrain development; midbrain-hindbrain boundary morphogenesis; negative regulation of neural precursor cell proliferation; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; rRNA binding; spermatogenesis; third ventricle development; transcription, DNA-dependent; zinc ion binding",PF00646;PF16866;PF02008;,,,,,,,,,KDM2B_HUMAN,Homo sapiens (Human),"embryonic camera-type eye morphogenesis [GO:0048596]; forebrain development [GO:0030900]; fourth ventricle development [GO:0021592]; hindbrain development [GO:0030902]; histone H2A monoubiquitination [GO:0035518]; initiation of neural tube closure [GO:0021993]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of stem cell population maintenance [GO:1902459]; spermatogenesis [GO:0007283]; third ventricle development [GO:0021678]; transcription, DNA-templated [GO:0006351]" comp143071_c0_seq9,480,42.9167,0.52490307,0,0,,2.00E-57,Q9Y2K7,Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A),GO:0070544; GO:0051864; GO:0000790; GO:0005654; GO:0006355; GO:0006351; GO:0045322; GO:0008270,"histone H3-K36 demethylation; histone demethylase activity (H3-K36 specific); nuclear chromatin; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent; unmethylated CpG binding; zinc ion binding",PF00646;PF02373;PF16866;PF02008;,2.00E-52,CHOYP_KDM2B.1.1,,,,,,,KDM2A_HUMAN,Homo sapiens (Human),"double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143072_c0_seq3,4443,51.4067,0.41604741,15,0,,,,,,,,,1.00E-168,CHOYP_LOC585963.2.2,,,,,,,,, comp143072_c0_seq4,4443,51.3617,0.41325082,5,0,,,,,,,,,2.00E-128,CHOYP_TRIADDRAFT_51343.2.2,,,,,,,,, comp143072_c0_seq5,2632,51.7477,0.46083196,6,0,,,,,,,,,2.00E-125,CHOYP_LOC585963.2.2,,,,,,,,, comp143072_c0_seq9,1181,51.0584,0.39360668,0,0,,4.00E-08,Q9SJK6,Putative white-brown complex homolog protein 30 (Putative non-intrinsic ABC protein 12) (WBC-related protein 1),Putative white-brown complex homolog protein 30 (Putative non-intrinsic ABC protein 12) (WBC-related protein 1),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF00005;,,,,,,,,,WBC30_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp143074_c0_seq9,1158,29.4473,0.31994503,0,0,,,,,,,,,,,6.00E-11,ruditapes_c4938,,,,,,, comp143075_c1_seq1,1536,43.4245,0.67647195,381,540,,3.00E-166,Q6DFC2,Coiled-coil domain-containing protein 77,Coiled-coil domain-containing protein 77,,,,0,CHOYP_LOC100376772.1.1,,,,,,,CCD77_XENLA,Xenopus laevis (African clawed frog), comp143076_c0_seq1,3724,40.8969,0.63854318,47,22,,7.00E-155,P35611,Alpha-adducin (Erythrocyte adducin subunit alpha),Alpha-adducin (Erythrocyte adducin subunit alpha),GO:0008290; GO:0051015; GO:0051017; GO:0006987; GO:0051016; GO:0000902; GO:0006884; GO:0006921; GO:0044267; GO:0071300; GO:0005829; GO:0043197; GO:0030218; GO:0020027; GO:0048873; GO:0001701; GO:0035264; GO:0005634; GO:0048471; GO:0005886; GO:0045766; GO:0045807; GO:0032092; GO:0014069; GO:0030507; GO:0005198,F-actin capping protein complex; actin filament binding; actin filament bundle assembly; activation of signaling protein activity involved in unfolded protein response; barbed-end actin filament capping; cell morphogenesis; cell volume homeostasis; cellular component disassembly involved in execution phase of apoptosis; cellular protein metabolic process; cellular response to retinoic acid; cytosol; dendritic spine; erythrocyte differentiation; hemoglobin metabolic process; homeostasis of number of cells within a tissue; in utero embryonic development; multicellular organism growth; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of angiogenesis; positive regulation of endocytosis; positive regulation of protein binding; postsynaptic density; spectrin binding; structural molecule activity,PF00596;,1.00E-179,CHOYP_ADD.2.5,,,,,,,ADDA_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; IRE1-mediated unfolded protein response [GO:0036498]; multicellular organism growth [GO:0035264]; positive regulation of protein binding [GO:0032092]; transmembrane transport [GO:0055085] comp143076_c0_seq2,2743,28.2537,0.51297945,42,151,,,,,,,,,,,7.00E-21,ruditapes_c30618,,,,,,, comp143076_c0_seq4,3790,40.5013,0.62121389,27,8,,9.00E-156,P35611,Alpha-adducin (Erythrocyte adducin subunit alpha),Alpha-adducin (Erythrocyte adducin subunit alpha),GO:0008290; GO:0051015; GO:0051017; GO:0006987; GO:0051016; GO:0000902; GO:0006884; GO:0006921; GO:0044267; GO:0071300; GO:0005829; GO:0043197; GO:0030218; GO:0020027; GO:0048873; GO:0001701; GO:0035264; GO:0005634; GO:0048471; GO:0005886; GO:0045766; GO:0045807; GO:0032092; GO:0014069; GO:0030507; GO:0005198,F-actin capping protein complex; actin filament binding; actin filament bundle assembly; activation of signaling protein activity involved in unfolded protein response; barbed-end actin filament capping; cell morphogenesis; cell volume homeostasis; cellular component disassembly involved in execution phase of apoptosis; cellular protein metabolic process; cellular response to retinoic acid; cytosol; dendritic spine; erythrocyte differentiation; hemoglobin metabolic process; homeostasis of number of cells within a tissue; in utero embryonic development; multicellular organism growth; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of angiogenesis; positive regulation of endocytosis; positive regulation of protein binding; postsynaptic density; spectrin binding; structural molecule activity,PF00596;,,,6.00E-11,ruditapes_c16612,,,,,ADDA_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; IRE1-mediated unfolded protein response [GO:0036498]; multicellular organism growth [GO:0035264]; positive regulation of protein binding [GO:0032092]; transmembrane transport [GO:0055085] comp143076_c0_seq5,3612,40.4208,0.62115686,4,17,,3.00E-154,Q02645,Protein hu-li tai shao (Adducin-like protein),Protein hu-li tai shao (Adducin-like protein),GO:0007527; GO:0051297; GO:0007282; GO:0005856; GO:0048135; GO:0008302; GO:0035183; GO:0045169; GO:0007294; GO:0005811; GO:0000212; GO:0030723; GO:0072499; GO:0005886; GO:0045214; GO:0045170; GO:0030721; GO:0030724,"adult somatic muscle development; centrosome organization; cystoblast division; cytoskeleton; female germ-line cyst formation; female germline ring canal formation, actin assembly; female germline ring canal inner rim; fusome; germarium-derived oocyte fate determination; lipid particle; meiotic spindle organization; ovarian fusome organization; photoreceptor cell axon guidance; plasma membrane; sarcomere organization; spectrosome; spectrosome organization; testicular fusome organization",PF00596;,0,CHOYP_ADD.4.5,,,,,,,HTS_DROME,Drosophila melanogaster (Fruit fly),"actin filament bundle organization [GO:0061572]; adult somatic muscle development [GO:0007527]; axon guidance [GO:0007411]; centrosome organization [GO:0051297]; cystoblast division [GO:0007282]; female germ-line cyst formation [GO:0048135]; female germline ring canal formation, actin assembly [GO:0008302]; fusome organization [GO:0045478]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; locomotion involved in locomotory behavior [GO:0031987]; meiotic spindle organization [GO:0000212]; neuron cellular homeostasis [GO:0070050]; oogenesis [GO:0048477]; ovarian fusome organization [GO:0030723]; photoreceptor cell axon guidance [GO:0072499]; sarcomere organization [GO:0045214]; spectrosome organization [GO:0030721]; testicular fusome organization [GO:0030724]" comp143076_c0_seq6,3762,40.4572,0.62685328,1,37,,5.00E-155,P35611,Alpha-adducin (Erythrocyte adducin subunit alpha),Alpha-adducin (Erythrocyte adducin subunit alpha),GO:0008290; GO:0051015; GO:0051017; GO:0006987; GO:0051016; GO:0000902; GO:0006884; GO:0006921; GO:0044267; GO:0071300; GO:0005829; GO:0043197; GO:0030218; GO:0020027; GO:0048873; GO:0001701; GO:0035264; GO:0005634; GO:0048471; GO:0005886; GO:0045766; GO:0045807; GO:0032092; GO:0014069; GO:0030507; GO:0005198,F-actin capping protein complex; actin filament binding; actin filament bundle assembly; activation of signaling protein activity involved in unfolded protein response; barbed-end actin filament capping; cell morphogenesis; cell volume homeostasis; cellular component disassembly involved in execution phase of apoptosis; cellular protein metabolic process; cellular response to retinoic acid; cytosol; dendritic spine; erythrocyte differentiation; hemoglobin metabolic process; homeostasis of number of cells within a tissue; in utero embryonic development; multicellular organism growth; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of angiogenesis; positive regulation of endocytosis; positive regulation of protein binding; postsynaptic density; spectrin binding; structural molecule activity,PF00596;,0,CHOYP_ADD.2.5,,,2.00E-107,FP003042.p.cg.6,4,female gonad,ADDA_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; IRE1-mediated unfolded protein response [GO:0036498]; multicellular organism growth [GO:0035264]; positive regulation of protein binding [GO:0032092]; transmembrane transport [GO:0055085] comp143077_c1_seq4,2459,40.5856,0.56535024,443,2394,,0,Q1JQE0,SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski-interacting protein),SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski-interacting protein),GO:0046332; GO:0071146; GO:0071013; GO:0071300; GO:0042771; GO:0000398; GO:0000122; GO:0016363; GO:0043923; GO:0051571; GO:0048026; GO:0050769; GO:0045944; GO:0030511; GO:0070564; GO:0008024; GO:0048385; GO:0070562; GO:0042974; GO:0048384; GO:0003713; GO:0003714; GO:0006351; GO:0042809,"SMAD binding; SMAD3-SMAD4 protein complex; catalytic step 2 spliceosome; cellular response to retinoic acid; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; mRNA splicing, via spliceosome; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; positive regulation by host of viral transcription; positive regulation of histone H3-K4 methylation; positive regulation of mRNA splicing, via spliceosome; positive regulation of neurogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of vitamin D receptor signaling pathway; positive transcription elongation factor complex b; regulation of retinoic acid receptor signaling pathway; regulation of vitamin D receptor signaling pathway; retinoic acid receptor binding; retinoic acid receptor signaling pathway; transcription coactivator activity; transcription corepressor activity; transcription, DNA-dependent; vitamin D receptor binding",PF02731;,0,CHOYP_SNW1.2.2,,,,,,,SNW1_BOVIN,Bos taurus (Bovine),"cellular response to retinoic acid [GO:0071300]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinoic acid receptor signaling pathway [GO:0048384]; transcription, DNA-templated [GO:0006351]" comp143079_c0_seq1,3140,36.0191,0.50418927,0,11,,3.00E-63,Q9XZC8,Semaphorin-2A (Sema-2A) (Sema II),Semaphorin-2A (Sema-2A) (Sema II),GO:0030154; GO:0005576; GO:0016020; GO:0007399; GO:0004872,cell differentiation; extracellular region; membrane; nervous system development; receptor activity,PF01403;,,,,,,,,,SEM2A_SCHGR,Schistocerca gregaria (Desert locust),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp143079_c0_seq4,3292,35.8141,0.48808158,0,0,,4.00E-68,Q24323,Semaphorin-2A (Semaphorin-II) (Sema II),Semaphorin-2A (Semaphorin-II) (Sema II),GO:0007411; GO:0070983; GO:0042756; GO:0005576; GO:0007629; GO:0016020; GO:0004872; GO:0016201; GO:0007632,axon guidance; dendrite guidance; drinking behavior; extracellular region; flight behavior; membrane; receptor activity; synaptic target inhibition; visual behavior,PF01403;,,,,,,,,,SEM2A_DROME,Drosophila melanogaster (Fruit fly),adult behavior [GO:0030534]; axon guidance [GO:0007411]; dendrite guidance [GO:0070983]; drinking behavior [GO:0042756]; flight behavior [GO:0007629]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; olfactory bulb axon guidance [GO:0071678]; positive regulation of cell migration [GO:0030335]; salivary gland development [GO:0007431]; semaphorin-plexin signaling pathway [GO:0071526]; sensory neuron axon guidance [GO:0097374]; synaptic target inhibition [GO:0016201]; visual behavior [GO:0007632] comp143079_c0_seq6,3251,35.8966,0.49277709,0,0,,4.00E-68,Q24323,Semaphorin-2A (Semaphorin-II) (Sema II),Semaphorin-2A (Semaphorin-II) (Sema II),GO:0007411; GO:0070983; GO:0042756; GO:0005576; GO:0007629; GO:0016020; GO:0004872; GO:0016201; GO:0007632,axon guidance; dendrite guidance; drinking behavior; extracellular region; flight behavior; membrane; receptor activity; synaptic target inhibition; visual behavior,PF01403;,,,,,,,,,SEM2A_DROME,Drosophila melanogaster (Fruit fly),adult behavior [GO:0030534]; axon guidance [GO:0007411]; dendrite guidance [GO:0070983]; drinking behavior [GO:0042756]; flight behavior [GO:0007629]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; olfactory bulb axon guidance [GO:0071678]; positive regulation of cell migration [GO:0030335]; salivary gland development [GO:0007431]; semaphorin-plexin signaling pathway [GO:0071526]; sensory neuron axon guidance [GO:0097374]; synaptic target inhibition [GO:0016201]; visual behavior [GO:0007632] comp143079_c0_seq9,1634,37.8825,0.51453947,4,0,,1.00E-24,O88632,Semaphorin-3F (Semaphorin IV) (Sema IV),Semaphorin-3F (Semaphorin IV) (Sema IV),GO:0048846; GO:0045499; GO:0005576; GO:0016020; GO:0048843; GO:0021675; GO:0001755; GO:0004872; GO:1902285; GO:0061549; GO:0097490; GO:0097491,axon extension involved in axon guidance; chemorepellent activity; extracellular region; membrane; negative regulation of axon extension involved in axon guidance; nerve development; neural crest cell migration; receptor activity; semaphorin-plexin signaling pathway involved in neuron projection guidance; sympathetic ganglion development; sympathetic neuron projection extension; sympathetic neuron projection guidance,PF01403;,,,,,,,,,SEM3F_MOUSE,Mus musculus (Mouse),axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; nerve development [GO:0021675]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal nerve structural organization [GO:0021637]; ventral trunk neural crest cell migration [GO:0036486] comp143081_c0_seq1,2832,39.5127,0.51856461,884,3794,,1.00E-53,Q6DD45,Zinc finger CCHC domain-containing protein 8,Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8),GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,PF04046;PF00098;,6.00E-18,CHOYP_ZCCHC8.1.1,,,,,,,ZCHC8_XENLA,Xenopus laevis (African clawed frog), comp143082_c0_seq1,2970,44.6465,0.52932564,790,280,,0,P52034,6-phosphofructokinase (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase),ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase),GO:0003872; GO:0005945; GO:0005524; GO:0006002; GO:0006096,6-phosphofructokinase activity; 6-phosphofructokinase complex; ATP binding; fructose 6-phosphate metabolic process; glycolysis,PF00365;,0,CHOYP_K6PF.1.1,,,,,,,K6PF_DROME,Drosophila melanogaster (Fruit fly),fructose 6-phosphate metabolic process [GO:0006002]; glycolytic process [GO:0006096]; myoblast fusion [GO:0007520]; response to sucrose [GO:0009744]; somatic muscle development [GO:0007525] comp143082_c0_seq2,1184,41.723,0.41725382,15,14,,1.00E-114,Q5R636,6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphofructokinase 1) (Phosphohexokinase),"ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)",GO:0003872; GO:0005945; GO:0005524; GO:0006002; GO:0006096; GO:0046872,6-phosphofructokinase activity; 6-phosphofructokinase complex; ATP binding; fructose 6-phosphate metabolic process; glycolysis; metal ion binding,PF00365;,,,,,,,,,K6PP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),fructose 6-phosphate metabolic process [GO:0006002] comp143083_c0_seq2,1928,34.6992,0.3996308,2,33,,,,,,,,,4.00E-170,CHOYP_VATA.1.1,,,,,,,,, comp143083_c0_seq5,1203,46.384,0.39439231,41,141,,0,P31404,V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 3.6.3.14) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha),V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 3.6.3.14) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha),GO:0005524; GO:0015991; GO:0016324; GO:0005829; GO:0005902; GO:0005886; GO:0046961; GO:0033180,"ATP binding; ATP hydrolysis coupled proton transport; apical plasma membrane; cytosol; microvillus; plasma membrane; proton-transporting ATPase activity, rotational mechanism; proton-transporting V-type ATPase, V1 domain",PF00006;PF02874;PF16886;,0,CHOYP_VATA.1.1,,,,,,,VATA_BOVIN,Bos taurus (Bovine),ATP hydrolysis coupled proton transport [GO:0015991]; ATP metabolic process [GO:0046034] comp143084_c0_seq1,2185,35.6979,0.48897379,4,38,,3.00E-08,Q8BL66,Early endosome antigen 1,Early endosome antigen 1,GO:0005545; GO:0031410; GO:0005829; GO:0005769; GO:0031901; GO:0006897; GO:0019897; GO:0046872; GO:0005969; GO:0006906,1-phosphatidylinositol binding; cytoplasmic vesicle; cytosol; early endosome; early endosome membrane; endocytosis; extrinsic to plasma membrane; metal ion binding; serine-pyruvate aminotransferase complex; vesicle fusion,PF01363;,,,,,,,,,EEA1_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; vesicle fusion [GO:0006906] comp143084_c0_seq3,2202,36.376,0.50992829,0,35,,3.00E-102,Q5ZLY5,Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2),Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2),GO:0031901; GO:0005783; GO:0046872; GO:0005543; GO:0015031,early endosome membrane; endoplasmic reticulum; metal ion binding; phospholipid binding; protein transport,PF01363;PF00169;,9.00E-78,CHOYP_DANA_GF20914.1.1,,,,,,,PKHF2_CHICK,Gallus gallus (Chicken),protein transport [GO:0015031] comp143084_c0_seq4,2443,36.3078,0.48620202,0,0,,3.00E-14,Q96M96,"FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)","FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)",GO:0005794; GO:0005089; GO:0015629; GO:0030036; GO:0097190; GO:0005829; GO:0030175; GO:0046847; GO:0005085; GO:0030027; GO:0030032; GO:0046872; GO:0030035; GO:0048011; GO:0005543; GO:0043065; GO:0043088; GO:0008360; GO:0001726; GO:0031267; GO:0007264,Golgi apparatus; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton; actin cytoskeleton organization; apoptotic signaling pathway; cytosol; filopodium; filopodium assembly; guanyl-nucleotide exchange factor activity; lamellipodium; lamellipodium assembly; metal ion binding; microspike assembly; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; regulation of Cdc42 GTPase activity; regulation of cell shape; ruffle; small GTPase binding; small GTPase mediated signal transduction,PF01363;PF00169;PF00621;,,,,,,,,,FGD4_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; positive regulation of apoptotic process [GO:0043065]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp143084_c0_seq5,2157,35.6514,0.48187906,0,0,,6.00E-13,Q7Z3T8,Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),GO:0005545; GO:0030509; GO:0031901; GO:0016197; GO:0046872; GO:0005547; GO:0006622; GO:0008565; GO:0030100; GO:0016050,"1-phosphatidylinositol binding; BMP signaling pathway; early endosome membrane; endosomal transport; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; protein targeting to lysosome; protein transporter activity; regulation of endocytosis; vesicle organization",PF11979;PF01363;,,,,,,,,,ZFY16_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050] comp143084_c0_seq6,2426,35.6966,0.46636961,0,0,,7.00E-13,Q7Z3T8,Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),GO:0005545; GO:0030509; GO:0031901; GO:0016197; GO:0046872; GO:0005547; GO:0006622; GO:0008565; GO:0030100; GO:0016050,"1-phosphatidylinositol binding; BMP signaling pathway; early endosome membrane; endosomal transport; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; protein targeting to lysosome; protein transporter activity; regulation of endocytosis; vesicle organization",PF11979;PF01363;,,,,,,,,,ZFY16_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050] comp143084_c0_seq8,2174,36.3385,0.50326522,0,0,,3.00E-102,Q5ZLY5,Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2),Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2),GO:0031901; GO:0005783; GO:0046872; GO:0005543; GO:0015031,early endosome membrane; endoplasmic reticulum; metal ion binding; phospholipid binding; protein transport,PF01363;PF00169;,9.00E-78,CHOYP_DANA_GF20914.1.1,,,,,,,PKHF2_CHICK,Gallus gallus (Chicken),protein transport [GO:0015031] comp143085_c3_seq1,542,43.7269,0.38975154,12,102,,7.00E-106,A7MAZ3,Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1),Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1),GO:0005524; GO:0071566; GO:0048037; GO:0005737; GO:0046872; GO:0005634; GO:0016616; GO:0071569,"ATP binding; UFM1 activating enzyme activity; cofactor binding; cytoplasm; metal ion binding; nucleus; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; protein ufmylation",PF00899;,3.00E-120,CHOYP_UBA5.1.2,,,,,,,UBA5_BOVIN,Bos taurus (Bovine),cyclic threonylcarbamoyladenosine biosynthetic process [GO:0061504]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976] comp143086_c0_seq1,1690,35.3846,0.25239684,824,1687,,3.00E-54,Q503Y7,Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4),Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4),GO:0003677; GO:0005737; GO:0005730; GO:0003755; GO:0006457; GO:0000413; GO:0005819,DNA binding; cytoplasm; nucleolus; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; spindle,,3.00E-57,CHOYP_ISCW_ISCW006091.1.2,3.00E-86,ruditapes_c30119,,,,,PIN4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143087_c0_seq3,1465,37.4744,0.37153545,25,110,,2.00E-14,B5KFM4,SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1),SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1),GO:0006281; GO:0070876; GO:0010212,DNA repair; SOSS complex; response to ionizing radiation,PF15925;,1.00E-36,CHOYP_SOSSC.1.1,,,,,,,SOSSC_TAEGU,Taeniopygia guttata (Zebra finch) (Poephila guttata),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212] comp143090_c0_seq1,1232,39.5292,0.35417887,153,521,,2.00E-77,O75818,Ribonuclease P protein subunit p40 (RNaseP protein p40) (EC 3.1.26.5) (RNase P subunit 1),Ribonuclease P protein subunit p40 (RNaseP protein p40) (EC 3.1.26.5) (RNase P subunit 1),GO:0005655; GO:0004526; GO:0008033,nucleolar ribonuclease P complex; ribonuclease P activity; tRNA processing,PF08584;,,,2.00E-29,ruditapes_c13584,,,,,RPP40_HUMAN,Homo sapiens (Human),rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682] comp143093_c3_seq2,3065,35.9217,0.51892296,557,2424,,4.00E-55,Q32LM2,Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT),Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT),GO:0005737,cytoplasm,PF16546;PF00515;PF13181;,,,,,,,,,SGTA_BOVIN,Bos taurus (Bovine),positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071] comp143093_c3_seq3,2158,36.469,0.4213506,94,298,,1.00E-55,Q96EQ0,Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2),Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2),,,PF16546;PF00515;PF13414;,3.00E-77,CHOYP_LOC100373484.1.1,,,,,,,SGTB_HUMAN,Homo sapiens (Human), comp143094_c0_seq1,3091,46.5222,0.47013604,1159,48,,0,Q9MBF8,"Dynein-1-beta heavy chain, flagellar inner arm I1 complex (1-beta DHC) (Dynein-1, subspecies f)","Dynein-1-beta heavy chain, flagellar inner arm I1 complex (1-beta DHC) (Dynein-1, subspecies f)",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYH2.1.1,,,,,,,DYH1B_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159] comp143094_c0_seq3,242,41.3223,0.29172167,3,0,,3.00E-12,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp143094_c1_seq2,1403,41.34,0.56054035,116,150,,6.00E-112,Q8BGC4,Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-),Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-),GO:0005739; GO:0016491; GO:0005777; GO:0008270,mitochondrion; oxidoreductase activity; peroxisome; zinc ion binding,PF08240;PF00107;,5.00E-54,CHOYP_ZADH2.1.3,,,,,,,ZADH2_MOUSE,Mus musculus (Mouse), comp143095_c0_seq3,6024,42.0319,0.68887389,210,728,,,,,,,,,,,3.00E-24,ruditapes_c27367,,,,,,, comp143101_c1_seq1,2227,38.8415,0.35207836,18,26,,2.00E-103,Q9R013,Cathepsin F (EC 3.4.22.41),Cathepsin F (EC 3.4.22.41),GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08246;PF00112;,1.00E-152,CHOYP_NEMVEDRAFT_V1G204928.2.2,,,,,,,CATF_MOUSE,Mus musculus (Mouse),proteolysis involved in cellular protein catabolic process [GO:0051603] comp143101_c1_seq2,2277,38.823,0.3322084,0,24,,3.00E-28,P25805,Trophozoite cysteine proteinase (TCP) (EC 3.4.22.-),Trophozoite cysteine proteinase (TCP) (EC 3.4.22.-),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF08246;PF00112;,,,,,,,,,CYSP_PLAFA,Plasmodium falciparum, comp143101_c1_seq3,1188,42.1717,0.29004737,0,0,,3.00E-12,P32957,Cysteine proteinase 4 (EC 3.4.22.-) (CC-IV) (Cysteine proteinase IV) (Fragment),Cysteine proteinase 4 (EC 3.4.22.-) (CC-IV) (Cysteine proteinase IV) (Fragment),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF00112;,,,,,,,,,CYSP4_CARCN,Vasconcellea cundinamarcensis (Mountain papaya) (Carica candamarcensis), comp143101_c1_seq5,1238,42.1648,0.27781948,0,0,,8.00E-41,P14658,Cysteine proteinase (EC 3.4.22.-),Cysteine proteinase (EC 3.4.22.-),GO:0004197; GO:0005764; GO:0009405; GO:0006508,cysteine-type endopeptidase activity; lysosome; pathogenesis; proteolysis,PF12131;PF08246;PF00112;,,,,,,,,,CYSP_TRYBB,Trypanosoma brucei brucei,pathogenesis [GO:0009405] comp143103_c0_seq1,2854,37.6664,0.87322231,270,1346,,1.00E-09,Q9U3W6,Protein mab-21,Protein mab-21,GO:0048568,embryonic organ development,PF03281;,,,,,,,,,MAB21_DROME,Drosophila melanogaster (Fruit fly), comp143104_c0_seq3,2531,41.051,0.47168764,880,2804,,7.00E-64,P27237,Oligopeptidase A (EC 3.4.24.70),Oligopeptidase A (EC 3.4.24.70),GO:0046872; GO:0004222; GO:0006508,metal ion binding; metalloendopeptidase activity; proteolysis,PF01432;,,,,,,,,,OPDA_SALTY,Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720),signal peptide processing [GO:0006465] comp143104_c0_seq4,2279,40.939,0.46540983,5214,12449,,0,P35623,"Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)","Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)",GO:0006563; GO:0005737; GO:0004372; GO:0006544; GO:0030170; GO:0035999,L-serine metabolic process; cytoplasm; glycine hydroxymethyltransferase activity; glycine metabolic process; pyridoxal phosphate binding; tetrahydrofolate interconversion,PF00464;,1.00E-172,CHOYP_LOC100371236.1.1,5.00E-35,ruditapes_c2371,,,,,GLYC_SHEEP,Ovis aries (Sheep),glycine metabolic process [GO:0006544]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] comp143105_c1_seq1,4391,43.3386,0.46616393,823,3037,,0,O54889,DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (A194) (RPA194),DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (A194) (RPA194),GO:0003677; GO:0005736; GO:0003899; GO:0009303; GO:0006360; GO:0008270,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; rRNA transcription; transcription from RNA polymerase I promoter; zinc ion binding,PF04997;PF00623;PF04983;PF05000;PF04998;,0,CHOYP_RPA1.2.2,,,,,,,RPA1_RAT,Rattus norvegicus (Rat),rRNA transcription [GO:0009303]; transcription from RNA polymerase I promoter [GO:0006360] comp143106_c0_seq2,1339,39.5071,0.32570793,0,0,,,,,,,,,1.00E-142,CHOYP_CK049.1.1,,,,,,,,, comp143106_c0_seq3,1422,38.256,0.38472476,0,0,,5.00E-82,Q6DGK9,UPF0705 protein C11orf49 homolog,UPF0705 protein C11orf49 homolog,,,,,,,,,,,,CK049_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143106_c0_seq6,1296,39.6605,0.35365782,0,0,,,,,,,,,1.00E-142,CHOYP_CK049.1.1,,,,,,,,, comp143106_c1_seq2,1888,44.4386,0.32351808,5,0,,5.00E-65,Q9DE07,Nibrin (Nijmegen breakage syndrome protein 1 homolog),Nibrin (Nijmegen breakage syndrome protein 1 homolog),GO:0030870; GO:0000781; GO:0000724; GO:0007126; GO:0007095; GO:0042405; GO:0005654; GO:0047485; GO:0048145; GO:0000723; GO:0008134,"Mre11 complex; chromosome, telomeric region; double-strand break repair via homologous recombination; meiosis; mitotic G2 DNA damage checkpoint; nuclear inclusion body; nucleoplasm; protein N-terminus binding; regulation of fibroblast proliferation; telomere maintenance; transcription factor binding",PF00533;PF00498;PF08599;PF16508;,,,,,,,,,NBN_CHICK,Gallus gallus (Chicken),DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitotic cell cycle checkpoint [GO:0007093]; mitotic G2 DNA damage checkpoint [GO:0007095]; regulation of fibroblast proliferation [GO:0048145]; signal transduction in response to DNA damage [GO:0042770]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723] comp143106_c1_seq4,1889,44.468,0.30124503,36,65,,5.00E-65,Q9DE07,Nibrin (Nijmegen breakage syndrome protein 1 homolog),Nibrin (Nijmegen breakage syndrome protein 1 homolog),GO:0030870; GO:0000781; GO:0000724; GO:0007126; GO:0007095; GO:0042405; GO:0005654; GO:0047485; GO:0048145; GO:0000723; GO:0008134,"Mre11 complex; chromosome, telomeric region; double-strand break repair via homologous recombination; meiosis; mitotic G2 DNA damage checkpoint; nuclear inclusion body; nucleoplasm; protein N-terminus binding; regulation of fibroblast proliferation; telomere maintenance; transcription factor binding",PF00533;PF00498;PF08599;PF16508;,,,,,,,,,NBN_CHICK,Gallus gallus (Chicken),DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitotic cell cycle checkpoint [GO:0007093]; mitotic G2 DNA damage checkpoint [GO:0007095]; regulation of fibroblast proliferation [GO:0048145]; signal transduction in response to DNA damage [GO:0042770]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723] comp143107_c1_seq1,1982,43.7941,0.51868888,195,813,,0,Q9H2U1,Probable ATP-dependent RNA helicase DHX36 (EC 3.6.4.13) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE),ATP-dependent RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAH box protein 36) (G4-resolvase 1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE),GO:0005524; GO:0008026; GO:0005829; GO:0003725; GO:0045087; GO:0005634; GO:0032481; GO:0043330; GO:0009615,ATP binding; ATP-dependent helicase activity; cytosol; double-stranded RNA binding; innate immune response; nucleus; positive regulation of type I interferon production; response to exogenous dsRNA; response to virus,PF00270;PF04408;PF00271;PF07717;,3.00E-64,CHOYP_SI_DKEY-119O24.1.1.1,,,,,,,DHX36_HUMAN,Homo sapiens (Human),"ossification [GO:0001503]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]" comp143108_c0_seq1,2106,41.9278,0.4500449,279,2188,,7.00E-169,O15213,WD repeat-containing protein 46 (WD repeat-containing protein BING4),WD repeat-containing protein 46 (WD repeat-containing protein BING4),,,PF08149;,9.00E-97,CHOYP_BRAFLDRAFT_89920.1.1,,,,,,,WDR46_HUMAN,Homo sapiens (Human),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of protein targeting to mitochondrion [GO:1903955]; rRNA processing [GO:0006364]" comp143109_c0_seq1,361,38.2271,0.30828425,7,5,,2.00E-22,Q6INV3,Leucine-rich repeat-containing protein 57,Leucine-rich repeat-containing protein 57,,,PF13855;,2.00E-14,CHOYP_LRC57.1.1,,,,,,,LRC57_XENLA,Xenopus laevis (African clawed frog), comp143110_c0_seq1,3245,33.8983,0.45345604,2773,18607,,1.00E-113,Q5U305,ER lumen protein retaining receptor 2 (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2),ER lumen protein-retaining receptor 2 (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2),GO:0046923; GO:0005801; GO:0005783; GO:0005789; GO:0016021; GO:0006621; GO:0015031; GO:0016192,ER retention sequence binding; cis-Golgi network; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein retention in ER lumen; protein transport; vesicle-mediated transport,PF00810;,4.00E-122,CHOYP_ERD22.1.1,,,,,,,ERD22_RAT,Rattus norvegicus (Rat),protein retention in ER lumen [GO:0006621]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp143111_c1_seq1,3060,46.1438,0.57356752,1528,6288,,0,Q6GL41,DNA replication licensing factor mcm4 (EC 3.6.4.12) (Minichromosome maintenance protein 4),DNA replication licensing factor mcm4 (EC 3.6.4.12) (Minichromosome maintenance protein 4),GO:0005524; GO:0006200; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0000785; GO:0046872; GO:0005634; GO:0030174,ATP binding; ATP catabolic process; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; chromatin; metal ion binding; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF14551;,0,CHOYP_MCM4.1.1,,,2.00E-99,AM859520.p.cg.6,9,,MCM4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp143114_c0_seq1,1469,40.6399,1.09109362,40,226,,,,,,,,,2.00E-39,CHOYP_BRAFLDRAFT_106563.4.5,,,,,,,,, comp143116_c0_seq1,1198,45.2421,0.44828047,0,0,,6.00E-30,Q5UQ08,Putative ankyrin repeat protein R787,Putative ankyrin repeat protein R787,,,PF12796;,0,CHOYP_ANR17.1.2,,,,,,,YR787_MIMIV,Acanthamoeba polyphaga mimivirus (APMV), comp143116_c0_seq10,6313,47.0458,0.4588119,0,0,,2.00E-27,Q71S21,Inversin-B,Inversin-B,GO:0016055; GO:0005737; GO:0005856; GO:0007275,Wnt receptor signaling pathway; cytoplasm; cytoskeleton; multicellular organismal development,PF12796;PF00612;,,,,,,,,,INVSB_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp143116_c0_seq11,7786,44.3617,0.44916403,0,0,,7.00E-38,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,0,CHOYP_ANR17.1.2,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp143116_c0_seq12,5487,47.7492,0.46812507,0,0,,0,O75179,Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16),Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16),GO:0003723; GO:0001955; GO:0005737; GO:0019048; GO:0051151; GO:0005634,RNA binding; blood vessel maturation; cytoplasm; modulation by virus of host morphology or physiology; negative regulation of smooth muscle cell differentiation; nucleus,PF12796;PF00013;,,,,,,,,,ANR17_HUMAN,Homo sapiens (Human),blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]; viral process [GO:0016032] comp143116_c0_seq2,1894,48.2049,0.50820158,0,0,,0,O75179,Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16),Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16),GO:0003723; GO:0001955; GO:0005737; GO:0019048; GO:0051151; GO:0005634,RNA binding; blood vessel maturation; cytoplasm; modulation by virus of host morphology or physiology; negative regulation of smooth muscle cell differentiation; nucleus,PF12796;PF00013;,0,CHOYP_ANR17.1.2,,,,,,,ANR17_HUMAN,Homo sapiens (Human),blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]; viral process [GO:0016032] comp143116_c0_seq3,6978,44.6116,0.45533387,0,0,,0,Q9VCA8,Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein),Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein),GO:0003723; GO:0019730; GO:0051298; GO:0001751; GO:0005811; GO:0043066; GO:0046427; GO:0007169,RNA binding; antimicrobial humoral response; centrosome duplication; compound eye photoreceptor cell differentiation; lipid particle; negative regulation of apoptotic process; positive regulation of JAK-STAT cascade; transmembrane receptor protein tyrosine kinase signaling pathway,PF12796;PF00013;,,,,,,,,,ANKHM_DROME,Drosophila melanogaster (Fruit fly),antimicrobial humoral response [GO:0019730]; cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; compound eye photoreceptor cell differentiation [GO:0001751]; negative regulation of apoptotic process [GO:0043066]; positive regulation of JAK-STAT cascade [GO:0046427]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp143116_c0_seq5,1592,46.9849,0.45849661,0,0,,6.00E-41,Q7T163,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0016021; GO:0005770; GO:0007399,integral to membrane; late endosome; nervous system development,PF00023;PF12796;PF07693;,,,,,,,,,KDIS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859] comp143116_c0_seq6,2288,48.9073,0.50164375,0,0,,0,Q99NH0,Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein),Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein),GO:0003723; GO:0001955; GO:0005737; GO:0007492; GO:0051151; GO:0005634,RNA binding; blood vessel maturation; cytoplasm; endoderm development; negative regulation of smooth muscle cell differentiation; nucleus,PF12796;PF00013;,0,CHOYP_ANR17.1.2,,,,,,,ANR17_MOUSE,Mus musculus (Mouse),blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] comp143116_c0_seq7,7804,44.3747,0.44784704,0,0,,2.00E-143,Q21920,Ankyrin repeat and KH domain-containing protein R11A8.7,Ankyrin repeat and KH domain-containing protein R11A8.7,GO:0003723; GO:0005737,RNA binding; cytoplasm,PF12796;PF13606;PF00013;,,,,,,,,,ANKHM_CAEEL,Caenorhabditis elegans, comp143116_c0_seq8,6960,44.5977,0.45682912,0,0,,0,O75179,Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16),Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16),GO:0003723; GO:0001955; GO:0005737; GO:0019048; GO:0051151; GO:0005634,RNA binding; blood vessel maturation; cytoplasm; modulation by virus of host morphology or physiology; negative regulation of smooth muscle cell differentiation; nucleus,PF12796;PF00013;,0,CHOYP_ANR17.1.2,,,,,,,ANR17_HUMAN,Homo sapiens (Human),blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]; viral process [GO:0016032] comp143120_c0_seq1,7975,47.4107,0.49243977,4117,21839,,3.00E-108,P17139,Collagen alpha-1(IV) chain,Collagen alpha-1(IV) chain,GO:0005604; GO:0005581; GO:0009790; GO:0030198; GO:0005201; GO:0007517; GO:0002119; GO:0050714,basement membrane; collagen; embryo development; extracellular matrix organization; extracellular matrix structural constituent; muscle organ development; nematode larval development; positive regulation of protein secretion,PF01413;PF01391;,2.00E-98,CHOYP_CO4A2.1.2,,,,,,,CO4A1_CAEEL,Caenorhabditis elegans,embryo development ending in birth or egg hatching [GO:0009792]; extracellular matrix organization [GO:0030198]; muscle organ development [GO:0007517]; nematode larval development [GO:0002119]; positive regulation of protein secretion [GO:0050714] comp143125_c0_seq2,2702,42.45,0.94181198,0,80,,0,Q9TT16,Chloride transport protein 6 (Chloride channel protein 6) (ClC-6),Chloride transport protein 6 (Chloride channel protein 6) (ClC-6),GO:0005524; GO:0015297; GO:0010008; GO:0016021; GO:0005247,ATP binding; antiporter activity; endosome membrane; integral to membrane; voltage-gated chloride channel activity,PF00571;PF00654;,1.00E-32,CHOYP_CLCN6.1.1,6.00E-16,ruditapes_c19488,,,,,CLCN6_RABIT,Oryctolagus cuniculus (Rabbit), comp143126_c0_seq1,539,44.5269,0.37510549,32,76,,4.00E-17,Q55GA4,Cell division control protein 45 homolog,Cell division control protein 45 homolog,GO:0006270; GO:0007049; GO:0005634,DNA replication initiation; cell cycle; nucleus,PF02724;,,,,,,,,,CDC45_DICDI,Dictyostelium discoideum (Slime mold),DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication preinitiation complex assembly [GO:1902977]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]; regulation of chromatin silencing at telomere [GO:0031938] comp143126_c0_seq2,1001,37.6623,0.67838287,53,120,,3.00E-105,O75419,Cell division control protein 45 homolog (PORC-PI-1),Cell division control protein 45 homolog (PORC-PI-1),GO:0000076; GO:0006270; GO:0006271; GO:0005813; GO:0005737; GO:0005654; GO:0000083,DNA replication checkpoint; DNA replication initiation; DNA strand elongation involved in DNA replication; centrosome; cytoplasm; nucleoplasm; regulation of transcription involved in G1/S transition of mitotic cell cycle,PF02724;,2.00E-114,CHOYP_LOC753011.1.1,,,,,,,CDC45_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic DNA replication preinitiation complex assembly [GO:1902977]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]; regulation of chromatin silencing at telomere [GO:0031938]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] comp143127_c0_seq1,1055,40.3791,0.37804612,1277,4865,,9.00E-40,P70097,"Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)","Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)",GO:0009055; GO:0020037; GO:0016021; GO:0046872; GO:0005749; GO:0000104; GO:0006099,electron carrier activity; heme binding; integral to membrane; metal ion binding; mitochondrial respiratory chain complex II; succinate dehydrogenase activity; tricarboxylic acid cycle,PF01127;,1.00E-22,CHOYP_SDHC.1.1,6.00E-30,ruditapes2_c1889,,,,,C560_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),tricarboxylic acid cycle [GO:0006099] comp143130_c0_seq1,1201,41.5487,0.48569615,71,538,,4.00E-83,Q75QN2,Integrator complex subunit 8 (Int8) (Protein kaonashi-1),Integrator complex subunit 8 (Int8) (Protein kaonashi-1),GO:0032039; GO:0016180,integrator complex; snRNA processing,,4.00E-92,CHOYP_BRAFLDRAFT_117675.1.1,,,,,,,INT8_HUMAN,Homo sapiens (Human),snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp143131_c0_seq9,1776,33.5586,0.50071587,2,119,,,,,,,,,,,8.00E-12,ruditapes_c3510,,,,,,, comp143132_c0_seq1,2032,36.8602,0.46181534,15,101,,2.00E-12,Q7U0Y2,Acyl-CoA dehydrogenase fadE12 (EC 1.3.99.-),Acyl-CoA dehydrogenase fadE12 (EC 1.3.99.-),GO:0003995; GO:0050660,acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding,PF00441;PF02770;PF02771;,4.00E-171,CHOYP_IVD.1.2,,,,,,,ACDC_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp143132_c0_seq2,1944,36.8313,0.46843402,0,8,,2.00E-109,Q5RBD5,"Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)","Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)",GO:0003995; GO:0050660; GO:0006552; GO:0005759,acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; leucine catabolic process; mitochondrial matrix,PF00441;PF02770;PF02771;,4.00E-170,CHOYP_IVD.1.2,,,,,,,IVD_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),leucine catabolic process [GO:0006552] comp143132_c0_seq3,981,36.7992,0.46452272,37,234,,3.00E-64,Q9JHI5,"Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)","Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)",GO:0050660; GO:0008470; GO:0006552; GO:0005759; GO:0031966; GO:0005739,flavin adenine dinucleotide binding; isovaleryl-CoA dehydrogenase activity; leucine catabolic process; mitochondrial matrix; mitochondrial membrane; mitochondrion,PF00441;PF02770;PF02771;,,,,,,,,,IVD_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]; lipid homeostasis [GO:0055088] comp143133_c0_seq3,1935,34.0052,0.44934653,17,68,,3.00E-66,Q58CS8,N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma),N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma),GO:0005794; GO:0005576,Golgi apparatus; extracellular region,PF13015;,5.00E-49,CHOYP_GNPTG.2.2,,,,,,,GNPTG_BOVIN,Bos taurus (Bovine),carbohydrate phosphorylation [GO:0046835] comp143134_c1_seq1,691,43.5601,0.679341,45,4,,2.00E-47,Q7TSV3,Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc finger protein) (MCH-R1-interacting zinc finger protein),Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc finger protein) (MCH-R1-interacting zinc finger protein),GO:0005794; GO:0046872; GO:0005886; GO:0045202,Golgi apparatus; metal ion binding; plasma membrane; synapse,PF13392;PF01753;,7.00E-23,CHOYP_ZMY19.1.1,,,,,,,ZMY19_RAT,Rattus norvegicus (Rat), comp143134_c1_seq2,345,46.3768,1.03800872,31,0,,,,,,,,,2.00E-12,CHOYP_ZMY19.1.1,,,,,,,,, comp143134_c2_seq2,5710,42.1891,0.40362993,507,1495,,3.00E-177,Q14690,Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11),Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11),GO:0003723; GO:0005829; GO:0006397; GO:0005730; GO:0005634; GO:0006364,RNA binding; cytosol; mRNA processing; nucleolus; nucleus; rRNA processing,PF00575;PF05843;,5.00E-67,CHOYP_RRP5.1.1,,,,,,,RRP5_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; rRNA processing [GO:0006364] comp143135_c0_seq1,793,48.802,0.52191143,0,0,,4.00E-09,Q90ZD5,Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin),Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin),GO:0005576; GO:0007275,extracellular region; multicellular organismal development,PF00093;,,,,,,,,,CRDL1_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275] comp143135_c0_seq10,591,47.7157,0.39505272,30,0,,3.00E-35,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp143135_c0_seq3,1083,43.4903,0.55484107,3,0,,2.00E-08,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp143135_c0_seq6,4753,44.0774,0.4731521,53,12,,2.00E-59,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp143135_c0_seq7,788,47.7157,0.55174914,0,0,,7.00E-10,Q76LD0,Chordin-like protein 1 (Kohjirin) (Neuralin-1) (Neurogenesin-1) (Ventroptin),Chordin-like protein 1 (Kohjirin) (Neuralin-1) (Neurogenesin-1) (Ventroptin),GO:0001709; GO:0048749; GO:0005576; GO:0030182; GO:0001503,cell fate determination; compound eye development; extracellular region; neuron differentiation; ossification,PF00093;,,,,,,,,,CRDL1_RAT,Rattus norvegicus (Rat),cell fate determination [GO:0001709]; compound eye development [GO:0048749]; eye development [GO:0001654]; negative regulation of BMP signaling pathway [GO:0030514]; neuron differentiation [GO:0030182]; ossification [GO:0001503] comp143135_c0_seq9,4406,43.5996,0.46243031,0,0,,5.00E-20,P06845,Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase),Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase),GO:0042438; GO:0046872; GO:0004503,melanin biosynthetic process; metal ion binding; monophenol monooxygenase activity,PF00264;,9.00E-12,CHOYP_LOC100186692.1.1,,,,,,,TYRO_STRGA,Streptomyces glaucescens,melanin biosynthetic process [GO:0042438] comp143137_c0_seq1,5055,44.8665,0.48769872,68,0,,2.00E-23,Q96AY4,Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0000922,cell division; cytoplasm; microtubule organizing center; midbody; mitosis; spindle pole,PF12770;PF13176;PF13181;,,,,,,,,,TTC28_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp143137_c0_seq2,5105,44.4858,0.48337642,150,3,,2.00E-13,Q32LM2,Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT),Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT),GO:0005737,cytoplasm,PF16546;PF00515;PF13181;,1.00E-41,CHOYP_LOC100374969.1.1,,,,,,,SGTA_BOVIN,Bos taurus (Bovine),positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071] comp143142_c0_seq1,3733,44.8433,0.56676217,3,2,,0,O75051,Plexin-A2 (Semaphorin receptor OCT),Plexin-A2 (Semaphorin receptor OCT),GO:0007411; GO:0051642; GO:0021935; GO:0005887; GO:0005622; GO:0060174; GO:0021915; GO:0060037; GO:0030334; GO:0017154; GO:0002116; GO:0001756,axon guidance; centrosome localization; cerebellar granule cell precursor tangential migration; integral to plasma membrane; intracellular; limb bud formation; neural tube development; pharyngeal system development; regulation of cell migration; semaphorin receptor activity; semaphorin receptor complex; somitogenesis,PF08337;PF01437;PF01403;PF01833;,7.00E-133,CHOYP_ISCW_ISCW007151.2.2,,,,,,,PLXA2_HUMAN,Homo sapiens (Human),branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] comp143142_c0_seq3,2589,44.8049,0.56591527,0,0,,2.00E-24,Q09YN5,Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),GO:0005524; GO:0016021; GO:0007275; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;PF01403;PF01833;,,,,,,,,,MET_RABIT,Oryctolagus cuniculus (Rabbit),branching morphogenesis of an epithelial tube [GO:0048754]; endothelial cell morphogenesis [GO:0001886]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp143142_c0_seq4,3682,45.0842,0.55794987,22,3,,0,O75051,Plexin-A2 (Semaphorin receptor OCT),Plexin-A2 (Semaphorin receptor OCT),GO:0007411; GO:0051642; GO:0021935; GO:0005887; GO:0005622; GO:0060174; GO:0021915; GO:0060037; GO:0030334; GO:0017154; GO:0002116; GO:0001756,axon guidance; centrosome localization; cerebellar granule cell precursor tangential migration; integral to plasma membrane; intracellular; limb bud formation; neural tube development; pharyngeal system development; regulation of cell migration; semaphorin receptor activity; semaphorin receptor complex; somitogenesis,PF08337;PF01437;PF01403;PF01833;,8.00E-132,CHOYP_ISCW_ISCW007151.2.2,,,,,,,PLXA2_HUMAN,Homo sapiens (Human),branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] comp143142_c0_seq6,2519,45.2958,0.54282945,0,0,,3.00E-92,Q9Y4D7,Plexin-D1,Plexin-D1,GO:0001525; GO:0007411; GO:0060666; GO:0043542; GO:0005887; GO:0005622; GO:0001569; GO:0045765; GO:0030334; GO:0017154; GO:0007416,angiogenesis; axon guidance; dichotomous subdivision of terminal units involved in salivary gland branching; endothelial cell migration; integral to plasma membrane; intracellular; patterning of blood vessels; regulation of angiogenesis; regulation of cell migration; semaphorin receptor activity; synapse assembly,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXD1_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; aorta development [GO:0035904]; branchiomotor neuron axon guidance [GO:0021785]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; endothelial cell migration [GO:0043542]; outflow tract morphogenesis [GO:0003151]; patterning of blood vessels [GO:0001569]; positive regulation of protein binding [GO:0032092]; regulation of angiogenesis [GO:0045765]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; synapse assembly [GO:0007416] comp143142_c0_seq7,2818,44.1093,0.58069764,0,0,,2.00E-177,P70207,Plexin-A2 (Plex 2) (Plexin-2),Plexin-A2 (Plex 2) (Plexin-2),GO:0051642; GO:0021935; GO:0005887; GO:0005622; GO:0060174; GO:0021915; GO:0060037; GO:0030334; GO:0017154; GO:0001756,centrosome localization; cerebellar granule cell precursor tangential migration; integral to plasma membrane; intracellular; limb bud formation; neural tube development; pharyngeal system development; regulation of cell migration; semaphorin receptor activity; somitogenesis,PF08337;PF01437;PF01403;PF01833;,5.00E-127,CHOYP_ISCW_ISCW007151.2.2,,,,,,,PLXA2_MOUSE,Mus musculus (Mouse),branchiomotor neuron axon guidance [GO:0021785]; cell surface receptor signaling pathway [GO:0007166]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] comp143142_c0_seq8,2468,45.5835,0.53944836,0,0,,8.00E-23,A1X150,Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),GO:0005524; GO:0016021; GO:0007275; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;PF01437;PF01403;PF01833;,,,,,,,,,MET_ECHTE,Echinops telfairi (Lesser hedgehog tenrec),positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp143142_c0_seq9,3588,45.3456,0.54924577,0,0,,1.00E-160,Q9HCM2,Plexin-A4,Plexin-A4,GO:0021960; GO:0007411; GO:0021793; GO:0021610; GO:0021615; GO:0016021; GO:0005622; GO:0005886; GO:0021784; GO:0048841; GO:0050923; GO:0017154; GO:0002116; GO:0071526; GO:0048485; GO:0021636; GO:0021644,anterior commissure morphogenesis; axon guidance; chemorepulsion of branchiomotor axon; facial nerve morphogenesis; glossopharyngeal nerve morphogenesis; integral to membrane; intracellular; plasma membrane; postganglionic parasympathetic nervous system development; regulation of axon extension involved in axon guidance; regulation of negative chemotaxis; semaphorin receptor activity; semaphorin receptor complex; semaphorin-plexin signaling pathway; sympathetic nervous system development; trigeminal nerve morphogenesis; vagus nerve morphogenesis,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA4_HUMAN,Homo sapiens (Human),anterior commissure morphogenesis [GO:0021960]; branchiomotor neuron axon guidance [GO:0021785]; chemorepulsion of branchiomotor axon [GO:0021793]; facial nerve structural organization [GO:0021612]; glossopharyngeal nerve morphogenesis [GO:0021615]; postganglionic parasympathetic fiber development [GO:0021784]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of negative chemotaxis [GO:0050923]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sympathetic nervous system development [GO:0048485]; trigeminal nerve structural organization [GO:0021637]; vagus nerve morphogenesis [GO:0021644] comp143145_c2_seq2,2475,34.6263,0.47703893,181,882,,1.00E-125,Q6GL89,Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha),Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha),GO:0005850; GO:0006417; GO:0003743,eukaryotic translation initiation factor 2 complex; regulation of translation; translation initiation factor activity,PF07541;PF00575;,2.00E-155,CHOYP_IF2A.1.1,3.00E-37,ruditapes2_lrc1969,,,,,IF2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to amino acid starvation [GO:0034198]; cellular response to UV [GO:0034644]; negative regulation of translational initiation in response to stress [GO:0032057]; response to endoplasmic reticulum stress [GO:0034976]; translational initiation [GO:0006413] comp143145_c3_seq1,1311,43.3257,0.77499511,4,3,,5.00E-31,Q5E9B6,Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3),Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3),GO:0043277; GO:0044255; GO:0071222; GO:0042632; GO:0004879; GO:0010887; GO:0050728; GO:0032369; GO:0043031; GO:0090188; GO:0048550; GO:0045861; GO:0090341; GO:0000122; GO:0045892; GO:0000790; GO:0005634; GO:0032270; GO:0010875; GO:2000189; GO:0045723; GO:0051006; GO:0010870; GO:0034145; GO:0045944; GO:0010867; GO:0032570; GO:0046965; GO:0043565; GO:0003707; GO:0032810; GO:0070328; GO:0008270,"apoptotic cell clearance; cellular lipid metabolic process; cellular response to lipopolysaccharide; cholesterol homeostasis; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; negative regulation of cholesterol storage; negative regulation of inflammatory response; negative regulation of lipid transport; negative regulation of macrophage activation; negative regulation of pancreatic juice secretion; negative regulation of pinocytosis; negative regulation of proteolysis; negative regulation of secretion of lysosomal enzymes; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nuclear chromatin; nucleus; positive regulation of cellular protein metabolic process; positive regulation of cholesterol efflux; positive regulation of cholesterol homeostasis; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; positive regulation of receptor biosynthetic process; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of triglyceride biosynthetic process; response to progesterone stimulus; retinoid X receptor binding; sequence-specific DNA binding; steroid hormone receptor activity; sterol response element binding; triglyceride homeostasis; zinc ion binding",PF00104;PF00105;,1.00E-92,CHOYP_LOC100313647.1.1,,,,,,,NR1H3_BOVIN,Bos taurus (Bovine),"cellular lipid metabolic process [GO:0044255]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of inflammatory response [GO:0050728]; negative regulation of macrophage activation [GO:0043031]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of proteolysis [GO:0045861]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol homeostasis [GO:2000188]; triglyceride homeostasis [GO:0070328]" comp143145_c3_seq2,1349,43.5137,0.85813212,0,14,,7.00E-22,Q94407,Nuclear hormone receptor family member nhr-48,Nuclear hormone receptor family member nhr-48,GO:0005634; GO:0043565; GO:0003700; GO:0043401; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone mediated signaling pathway; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00105;,1.00E-92,CHOYP_LOC100120260.1.1,,,,,,,NHR48_CAEEL,Caenorhabditis elegans,"steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]" comp143146_c2_seq1,1101,37.9655,0.46366416,53,28,,1.00E-66,Q5ZIL9,KIF1-binding protein homolog,KIF1-binding protein homolog,GO:0030154; GO:0005856; GO:0006839; GO:0005739; GO:0007399,cell differentiation; cytoskeleton; mitochondrial transport; mitochondrion; nervous system development,PF12309;,2.00E-18,CHOYP_KBP.1.1,,,,,,,KBP_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; mitochondrial transport [GO:0006839]; nervous system development [GO:0007399] comp143146_c4_seq1,392,41.8367,0.41808783,25,0,,6.00E-12,Q5ZIL9,KIF1-binding protein homolog,KIF1-binding protein homolog,GO:0030154; GO:0005856; GO:0006839; GO:0005739; GO:0007399,cell differentiation; cytoskeleton; mitochondrial transport; mitochondrion; nervous system development,PF12309;,,,,,,,,,KBP_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; mitochondrial transport [GO:0006839]; nervous system development [GO:0007399] comp143147_c0_seq2,2090,38.1818,0.50632534,196,296,,2.00E-85,Q32NW2,Leukocyte receptor cluster member 8 homolog,Leukocyte receptor cluster member 8 homolog,,,PF03399;,,,,,,,,,LENG8_XENLA,Xenopus laevis (African clawed frog), comp143148_c0_seq3,1846,35.2113,0.50198027,11,9,,2.00E-49,Q9H9Y6,DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),GO:0003677; GO:0005736; GO:0003899; GO:0005737; GO:0009790; GO:0007566; GO:0046872; GO:0017126; GO:0005654; GO:0009303; GO:0032549; GO:0006363; GO:0006362; GO:0006361,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; cytoplasm; embryo development; embryo implantation; metal ion binding; nucleologenesis; nucleoplasm; rRNA transcription; ribonucleoside binding; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter,PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;,5.00E-30,CHOYP_BRAFLDRAFT_223894.1.1,,,,,,,RPA2_HUMAN,Homo sapiens (Human),"embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp143148_c0_seq8,1951,34.7002,0.47086584,5,29,,7.00E-33,Q9P7X8,Probable DNA-directed RNA polymerase I subunit RPA2 (EC 2.7.7.6) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2),Probable DNA-directed RNA polymerase I subunit RPA2 (EC 2.7.7.6) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2),GO:0003677; GO:0005736; GO:0003899; GO:0046872; GO:0032549; GO:0006360,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; metal ion binding; ribonucleoside binding; transcription from RNA polymerase I promoter,PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;,,,,,,,,,RPA2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),transcription from RNA polymerase I promoter [GO:0006360] comp143148_c0_seq9,1015,39.1133,0.55449489,7,18,,5.00E-52,Q9H9Y6,DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),GO:0003677; GO:0005736; GO:0003899; GO:0005737; GO:0009790; GO:0007566; GO:0046872; GO:0017126; GO:0005654; GO:0009303; GO:0032549; GO:0006363; GO:0006362; GO:0006361,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; cytoplasm; embryo development; embryo implantation; metal ion binding; nucleologenesis; nucleoplasm; rRNA transcription; ribonucleoside binding; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter,PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;,3.00E-30,CHOYP_BRAFLDRAFT_223894.1.1,,,,,,,RPA2_HUMAN,Homo sapiens (Human),"embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp143149_c0_seq2,2557,36.7618,0.56600495,8,40,,2.00E-42,Q92990,Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein),Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein),GO:0031462; GO:0031463; GO:0031464; GO:0042692; GO:0042130; GO:0001843; GO:0050715; GO:0045086; GO:0042327; GO:0040029; GO:0032434; GO:0031625; GO:0055105; GO:0001570,"Cul2-RING ubiquitin ligase complex; Cul3-RING ubiquitin ligase complex; Cul4A-RING ubiquitin ligase complex; muscle cell differentiation; negative regulation of T cell proliferation; neural tube closure; positive regulation of cytokine secretion; positive regulation of interleukin-2 biosynthetic process; positive regulation of phosphorylation; regulation of gene expression, epigenetic; regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin protein ligase binding; ubiquitin-protein ligase inhibitor activity; vasculogenesis",PF08568;,,,,,,,,,GLMN_HUMAN,Homo sapiens (Human),"muscle cell differentiation [GO:0042692]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of phosphorylation [GO:0042327]; regulation of gene expression, epigenetic [GO:0040029]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; vasculogenesis [GO:0001570]" comp143150_c2_seq3,1446,41.2172,0.57827817,8,23,,1.00E-91,O60921,Checkpoint protein HUS1 (hHUS1),Checkpoint protein HUS1 (hHUS1),GO:0000077; GO:0006281; GO:0006260; GO:0005794; GO:0071479; GO:0030896; GO:0000724; GO:0009790; GO:0007093; GO:0008156; GO:0005730; GO:0005654; GO:0006468; GO:0001932; GO:0009411,DNA damage checkpoint; DNA repair; DNA replication; Golgi apparatus; cellular response to ionizing radiation; checkpoint clamp complex; double-strand break repair via homologous recombination; embryo development; mitotic cell cycle checkpoint; negative regulation of DNA replication; nucleolus; nucleoplasm; protein phosphorylation; regulation of protein phosphorylation; response to UV,PF04005;,7.00E-90,CHOYP_HUS1.1.1,,,,,,,HUS1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; embryo development [GO:0009790]; intra-S DNA damage checkpoint [GO:0031573]; meiotic DNA integrity checkpoint [GO:0044778]; mitotic DNA replication checkpoint [GO:0033314]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to UV [GO:0009411] comp143150_c2_seq4,1376,41.5698,0.59716041,0,8,,6.00E-55,Q8K572,Checkpoint protein HUS1B (mHUS1B),Checkpoint protein HUS1B (mHUS1B),GO:0000077; GO:0006281; GO:0030896; GO:0005730,DNA damage checkpoint; DNA repair; checkpoint clamp complex; nucleolus,PF04005;,7.00E-90,CHOYP_HUS1.1.1,,,,,,,HUS1B_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; intra-S DNA damage checkpoint [GO:0031573]; meiotic DNA integrity checkpoint [GO:0044778]; mitotic DNA replication checkpoint [GO:0033314]; nucleotide-excision repair [GO:0006289] comp143151_c0_seq1,1422,39.7328,0.36654492,0,0,,2.00E-09,Q22795,Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),GO:0009792; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"embryo development ending in birth or egg hatching; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET1_CAEEL,Caenorhabditis elegans,"embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143151_c0_seq10,1593,40.7407,0.33970758,0,0,,2.00E-09,Q22795,Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),GO:0009792; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"embryo development ending in birth or egg hatching; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET1_CAEEL,Caenorhabditis elegans,"embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143151_c0_seq13,1559,40.7954,0.34600974,0,0,,3.00E-08,Q071E0,N-lysine methyltransferase SETD8-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase SETD8-A) (EC 2.1.1.43) (SET domain-containing protein 8-A),N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A),GO:0051301; GO:0005694; GO:0009953; GO:0018024; GO:0007067; GO:0005634; GO:0010628; GO:0006355; GO:0006351,"cell division; chromosome; dorsal/ventral pattern formation; histone-lysine N-methyltransferase activity; mitosis; nucleus; positive regulation of gene expression; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET8A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143151_c0_seq19,1466,43.3834,0.61828771,0,0,,2.00E-09,Q22795,Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),GO:0009792; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"embryo development ending in birth or egg hatching; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET1_CAEEL,Caenorhabditis elegans,"embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143151_c0_seq2,1388,39.7695,0.37464113,0,0,,2.00E-08,Q071E0,N-lysine methyltransferase SETD8-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase SETD8-A) (EC 2.1.1.43) (SET domain-containing protein 8-A),N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A),GO:0051301; GO:0005694; GO:0009953; GO:0018024; GO:0007067; GO:0005634; GO:0010628; GO:0006355; GO:0006351,"cell division; chromosome; dorsal/ventral pattern formation; histone-lysine N-methyltransferase activity; mitosis; nucleus; positive regulation of gene expression; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET8A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143151_c0_seq21,1405,43.8434,0.6316404,0,0,,2.00E-08,Q071E0,N-lysine methyltransferase SETD8-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase SETD8-A) (EC 2.1.1.43) (SET domain-containing protein 8-A),N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A),GO:0051301; GO:0005694; GO:0009953; GO:0018024; GO:0007067; GO:0005634; GO:0010628; GO:0006355; GO:0006351,"cell division; chromosome; dorsal/ventral pattern formation; histone-lysine N-methyltransferase activity; mitosis; nucleus; positive regulation of gene expression; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET8A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143152_c0_seq1,1590,36.4151,0.65644898,4038,14359,,4.00E-109,P28024,Proteasome subunit beta type-4 (EC 3.4.25.1) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (Fragment),Proteasome subunit beta type-4 (EC 3.4.25.1) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (Fragment),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,3.00E-83,CHOYP_LOC101069759.1.1,1.00E-71,ruditapes2_c1142,,,,,PSB4_XENLA,Xenopus laevis (African clawed frog),proteolysis involved in cellular protein catabolic process [GO:0051603] comp143153_c0_seq1,3491,40.0745,0.43771272,440,2457,,0,Q0VA16,WD repeat-containing protein 70,WD repeat-containing protein 70,,,PF00400;,4.00E-110,CHOYP_WDR70.1.1,1.00E-39,ruditapes_c28106,,,,,WDR70_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143154_c0_seq2,2346,34.1858,0.39176946,91,197,,2.00E-88,P51950,CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Menage a trois) (RING finger protein MAT1),CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Menage a trois) (RING finger protein MAT1),GO:0007049; GO:0051301; GO:0005634; GO:0008270,cell cycle; cell division; nucleus; zinc ion binding,PF06391;PF17121;,9.00E-53,CHOYP_LOC100367313.1.1,,,,,,,MAT1_MARGL,Marthasterias glacialis (Spiny starfish),cell cycle [GO:0007049]; cell division [GO:0051301] comp143156_c4_seq10,2389,35.5379,0.51729314,2,52,,4.00E-101,Q6IR80,UPF0536 protein C12orf66 homolog,UPF0536 protein C12orf66 homolog,,,PF09404;,,,,,,,,,CL066_XENLA,Xenopus laevis (African clawed frog), comp143156_c4_seq4,2414,34.9627,0.50198601,18,161,,5.00E-101,Q6IR80,UPF0536 protein C12orf66 homolog,UPF0536 protein C12orf66 homolog,,,PF09404;,,,,,,,,,CL066_XENLA,Xenopus laevis (African clawed frog), comp143157_c0_seq2,1873,42.2851,0.60970866,99,120,,0,Q7Z4S6,Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62),Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;PF00400;,0,CHOYP_KI21A.2.2,,,,,,,KI21A_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp143157_c1_seq1,2678,44.6229,0.46542484,2,3,,3.00E-18,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp143157_c1_seq2,2286,44.5319,0.5297416,0,0,,1.00E-13,Q8YV57,Uncharacterized WD repeat-containing protein all2124,Uncharacterized WD repeat-containing protein all2124,GO:0004197; GO:0006508,cysteine-type endopeptidase activity; proteolysis,PF12894;PF00400;,,,,,,,,,Y2124_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp143157_c1_seq4,1311,43.5545,0.56164416,136,104,,2.00E-10,Q90640,Chromosome-associated kinesin KIF4 (Chromokinesin),Chromosome-associated kinesin KIF4 (Chromokinesin),GO:0005524; GO:0003677; GO:0005694; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005634,ATP binding; DNA binding; chromosome; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; nucleus,PF00225;,,,,,,,,,KIF4_CHICK,Gallus gallus (Chicken),microtubule-based movement [GO:0007018] comp143157_c1_seq5,2193,44.2316,0.54109274,0,0,,4.00E-115,Q9QXL2,Kinesin-like protein KIF21A,Kinesin-like protein KIF21A,GO:0005524; GO:0030424; GO:0005737; GO:0030425; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; axon; cytoplasm; dendrite; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;PF00400;,1.00E-95,CHOYP_KI21A.1.2,,,,,,,KI21A_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp143157_c1_seq6,2585,44.4487,0.47810518,0,0,,6.00E-149,Q7Z4S6,Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62),Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;PF00400;,,,,,,,,,KI21A_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp143160_c1_seq14,226,40.2655,1.67902696,25,75,,,,,,,,,1.00E-19,CHOYP_SMP_066940.4.11,3.00E-13,ruditapes_c19609,,,,,,, comp143160_c1_seq2,542,35.2399,1.57497189,174,378,,,,,,,,,2.00E-16,CHOYP_OSCP1.1.1,,,,,,,,, comp143160_c1_seq3,534,33.7079,1.41214673,10,20,,,,,,,,,1.00E-17,CHOYP_PHUM_PHUM375280.1.2,,,,,,,,, comp143160_c1_seq4,970,30.8247,1.17681245,138,428,,,,,,,,,2.00E-18,CHOYP_BRAFLDRAFT_87325.10.11,1.00E-19,ruditapes_c2399,,,,,,, comp143160_c1_seq7,1245,30.9237,1.05316896,68,674,,,,,,,,,3.00E-18,CHOYP_LOC100378898.1.10,,,,,,,,, comp143164_c0_seq1,1953,33.8966,0.44597222,0,0,,1.00E-14,Q9TRY0,"Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]","Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]",GO:0005528; GO:0044295; GO:0061077; GO:0005829; GO:0016020; GO:0005874; GO:0005739; GO:0031111; GO:0010977; GO:0005634; GO:0003755,FK506 binding; axonal growth cone; chaperone-mediated protein folding; cytosol; membrane; microtubule; mitochondrion; negative regulation of microtubule polymerization or depolymerization; negative regulation of neuron projection development; nucleus; peptidyl-prolyl cis-trans isomerase activity,PF00254;PF00515;PF07719;,,,,,,,,,FKBP4_BOVIN,Bos taurus (Bovine),chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977] comp143164_c0_seq3,1091,32.0807,0.39269051,5,36,,4.00E-14,Q43207,70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0003755; GO:0006457; GO:0000413; GO:0006950,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; response to stress,PF00254;PF00515;,,,,,,,,,FKB70_WHEAT,Triticum aestivum (Wheat),protein folding [GO:0006457] comp143164_c0_seq7,849,41.8139,0.57421427,15,158,,4.00E-77,A0JPF9,Isoprenoid synthase domain-containing protein (EC 2.7.7.-) (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein),Isoprenoid synthase domain-containing protein (EC 2.7.7.-) (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein),GO:0048854; GO:0008299; GO:0048747; GO:0016779; GO:0035269; GO:0060049,brain morphogenesis; isoprenoid biosynthetic process; muscle fiber development; nucleotidyltransferase activity; protein O-linked mannosylation; regulation of protein glycosylation,PF01128;,9.00E-29,CHOYP_LOC101160346.1.1,,,,,,,ISPD_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),brain morphogenesis [GO:0048854]; isoprenoid biosynthetic process [GO:0008299]; muscle fiber development [GO:0048747]; protein O-linked mannosylation [GO:0035269]; regulation of protein glycosylation [GO:0060049] comp143164_c0_seq8,1524,32.874,0.46352604,10,65,,7.00E-15,Q9TRY0,"Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]","Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]",GO:0005528; GO:0044295; GO:0061077; GO:0005829; GO:0016020; GO:0005874; GO:0005739; GO:0031111; GO:0010977; GO:0005634; GO:0003755,FK506 binding; axonal growth cone; chaperone-mediated protein folding; cytosol; membrane; microtubule; mitochondrion; negative regulation of microtubule polymerization or depolymerization; negative regulation of neuron projection development; nucleus; peptidyl-prolyl cis-trans isomerase activity,PF00254;PF00515;PF07719;,,,,,,,,,FKBP4_BOVIN,Bos taurus (Bovine),chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977] comp143165_c0_seq1,1887,42.7133,0.54244417,146,558,,0,Q4R550,"Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)","Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)",GO:0005524; GO:0004817; GO:0006423; GO:0005737; GO:0046872; GO:0000049,ATP binding; cysteine-tRNA ligase activity; cysteinyl-tRNA aminoacylation; cytoplasm; metal ion binding; tRNA binding,PF01406;,7.00E-79,CHOYP_SYCC.1.1,,,,,,,SYCC_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cysteinyl-tRNA aminoacylation [GO:0006423] comp143165_c0_seq2,278,52.8777,0.46535072,1,17,,,,,,,,,3.00E-47,CHOYP_MYSP.5.9,,,,,,,,, comp143166_c0_seq1,1909,42.3258,0.29296104,425,1338,,1.00E-51,Q3TZX8,Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9),Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9),GO:0005524; GO:0003723; GO:0000460; GO:0005730; GO:0051731,ATP binding; RNA binding; maturation of 5.8S rRNA; nucleolus; polynucleotide 5'-hydroxyl-kinase activity,PF16575;,,,,,,,,,NOL9_MOUSE,Mus musculus (Mouse),"cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; maturation of 5.8S rRNA [GO:0000460]" comp143167_c1_seq1,3553,33.718,0.46025775,2865,11730,,3.00E-108,P28075,Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit X),Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit X),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,4.00E-135,CHOYP_NEMVEDRAFT_V1G173323.2.2,0,ruditapes2_c1210,1.00E-134,BQ426799.p.cg.6,8,,PSB5_RAT,Rattus norvegicus (Rat),proteolysis involved in cellular protein catabolic process [GO:0051603] comp143168_c0_seq12,359,40.1114,0.55652606,7,0,,3.00E-11,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,6.00E-20,CHOYP_LOC100123553.1.1,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143169_c0_seq1,2665,39.1745,0.87427563,0,0,,7.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq10,2731,39.2896,0.90502704,0,0,,2.00E-12,P18238,"ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3)","ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3)",GO:0005471; GO:0009061; GO:0015886; GO:0016021; GO:0005743,ATP:ADP antiporter activity; anaerobic respiration; heme transport; integral to membrane; mitochondrial inner membrane,PF00153;,,,,,,,,,ADT3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),anaerobic respiration [GO:0009061]; heme transport [GO:0015886]; translation [GO:0006412]; transmembrane transport [GO:0055085] comp143169_c0_seq11,2688,39.3229,0.90798268,0,0,,4.00E-15,Q54MZ4,Mitochondrial substrate carrier family protein B,Mitochondrial substrate carrier family protein B,GO:0005509; GO:0016021; GO:0005743; GO:0005739; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF13499;PF00153;,,,,,,,,,MCFB_DICDI,Dictyostelium discoideum (Slime mold),translation [GO:0006412]; transmembrane transport [GO:0055085] comp143169_c0_seq12,2644,39.3722,0.87252327,0,0,,2.00E-18,P33303,Succinate/fumarate mitochondrial transporter (Regulator of acetyl-CoA synthase activity),Succinate/fumarate mitochondrial transporter (Regulator of acetyl-CoA synthase activity),GO:0016021; GO:0005743; GO:0005469,integral to membrane; mitochondrial inner membrane; succinate:fumarate antiporter activity,PF00153;,,,,,,,,,SFC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),fumarate transport [GO:0015741]; succinate transport [GO:0015744]; translation [GO:0006412] comp143169_c0_seq13,2407,39.302,0.87405517,0,0,,1.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq14,2416,39.0728,0.88035575,0,0,,1.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq15,2729,39.1352,0.89298853,0,0,,5.00E-11,Q5PQ27,Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),GO:0015217; GO:0080122; GO:0005347; GO:0043262; GO:0015228; GO:0016021; GO:0005743; GO:0005739,ADP transmembrane transporter activity; AMP transmembrane transporter activity; ATP transmembrane transporter activity; adenosine-diphosphatase activity; coenzyme A transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; mitochondrion,PF00153;,,,,,,,,,S2542_XENLA,Xenopus laevis (African clawed frog),ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349] comp143169_c0_seq16,2421,39.1574,0.87489479,33,0,,1.00E-57,O95258,Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14),Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14),GO:0009060; GO:0005887; GO:0005743; GO:0006839; GO:0005739; GO:0006810,aerobic respiration; integral to plasma membrane; mitochondrial inner membrane; mitochondrial transport; mitochondrion; transport,PF00153;,,,,,,,,,UCP5_HUMAN,Homo sapiens (Human),aerobic respiration [GO:0009060]; mitochondrial transport [GO:0006839]; proton transport [GO:0015992]; translation [GO:0006412]; transport [GO:0006810] comp143169_c0_seq17,2724,39.3906,0.90231171,0,0,,9.00E-12,A2ASZ8,Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),GO:0046034; GO:0060612; GO:0005509; GO:0070588; GO:0043010; GO:0045333; GO:0016021; GO:0005743; GO:0005739; GO:0035264; GO:0014823; GO:0002021; GO:0032094,ATP metabolic process; adipose tissue development; calcium ion binding; calcium ion transmembrane transport; camera-type eye development; cellular respiration; integral to membrane; mitochondrial inner membrane; mitochondrion; multicellular organism growth; response to activity; response to dietary excess; response to food,PF13499;PF13833;PF00153;,,,,,,,,,SCMC2_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412] comp143169_c0_seq18,2658,39.2777,0.87156901,0,0,,6.00E-15,Q9H0C2,"ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein)","ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein) [Cleaved into: ADP/ATP translocase 4, N-terminally processed]",GO:0005929; GO:0016021; GO:0005743; GO:0005739; GO:0055085; GO:0005215,cilium; integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport; transporter activity,PF00153;,,,,,,,,,ADT4_HUMAN,Homo sapiens (Human),translation [GO:0006412]; transmembrane transport [GO:0055085] comp143169_c0_seq19,2617,39.0906,0.87326905,0,0,,5.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq2,2663,39.0913,0.86829895,0,0,,7.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq21,2528,39.1614,0.86958457,0,0,,9.00E-46,B0G143,Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B),Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCPB_DICDI,Dictyostelium discoideum (Slime mold),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq22,2732,39.3485,0.89290145,0,0,,2.00E-09,Q86VD7,Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),GO:0015217; GO:0080122; GO:0005347; GO:0043262; GO:0015228; GO:0016021; GO:0005743; GO:0005739,ADP transmembrane transporter activity; AMP transmembrane transporter activity; ATP transmembrane transporter activity; adenosine-diphosphatase activity; coenzyme A transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; mitochondrion,PF00153;,,,,,,,,,S2542_HUMAN,Homo sapiens (Human),ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412] comp143169_c0_seq23,2542,39.0637,0.86865234,0,0,,3.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq24,2636,39.1123,0.87592113,0,0,,1.00E-08,A5DIS9,Mitochondrial thiamine pyrophosphate carrier 1,Mitochondrial thiamine pyrophosphate carrier 1,GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,,,,,,,,,TPC1_PICGU,Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii),thiamine pyrophosphate transport [GO:0030974] comp143169_c0_seq25,2680,39.1418,0.86091297,0,0,,3.00E-12,Q0V7M4,Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),GO:0005509; GO:0016021; GO:0005743; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF13499;PF13833;PF00153;,,,,,,,,,SCMC2_BOVIN,Bos taurus (Bovine),adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412] comp143169_c0_seq26,2679,39.0817,0.87330949,0,0,,2.00E-09,Q86VD7,Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),GO:0015217; GO:0080122; GO:0005347; GO:0043262; GO:0015228; GO:0016021; GO:0005743; GO:0005739,ADP transmembrane transporter activity; AMP transmembrane transporter activity; ATP transmembrane transporter activity; adenosine-diphosphatase activity; coenzyme A transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; mitochondrion,PF00153;,,,,,,,,,S2542_HUMAN,Homo sapiens (Human),ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412] comp143169_c0_seq27,2622,39.2067,0.8768744,0,0,,2.00E-18,P33303,Succinate/fumarate mitochondrial transporter (Regulator of acetyl-CoA synthase activity),Succinate/fumarate mitochondrial transporter (Regulator of acetyl-CoA synthase activity),GO:0016021; GO:0005743; GO:0005469,integral to membrane; mitochondrial inner membrane; succinate:fumarate antiporter activity,PF00153;,,,,,,,,,SFC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),fumarate transport [GO:0015741]; succinate transport [GO:0015744]; translation [GO:0006412] comp143169_c0_seq28,2497,39.2871,0.86448974,0,0,,2.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq3,2649,39.1091,0.86251415,1,0,,1.00E-104,P55851,Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8) (UCPH),Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8) (UCPH),GO:0032869; GO:0016021; GO:0005743; GO:0006839; GO:0015992; GO:0022904; GO:0070542; GO:0009749; GO:0001666; GO:0000303; GO:0044281,cellular response to insulin stimulus; integral to membrane; mitochondrial inner membrane; mitochondrial transport; proton transport; respiratory electron transport chain; response to fatty acid; response to glucose stimulus; response to hypoxia; response to superoxide; small molecule metabolic process,PF00153;,,,,,,,,,UCP2_HUMAN,Homo sapiens (Human),aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; female pregnancy [GO:0007565]; liver regeneration [GO:0097421]; mitochondrial transport [GO:0006839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; positive regulation of cell death [GO:0010942]; proton transport [GO:0015992]; regulation of mitochondrial membrane potential [GO:0051881]; response to fatty acid [GO:0070542]; response to hypoxia [GO:0001666]; response to superoxide [GO:0000303]; translation [GO:0006412]; transport [GO:0006810] comp143169_c0_seq30,2702,39.2302,0.90706006,0,0,,9.00E-12,A2ASZ8,Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),GO:0046034; GO:0060612; GO:0005509; GO:0070588; GO:0043010; GO:0045333; GO:0016021; GO:0005743; GO:0005739; GO:0035264; GO:0014823; GO:0002021; GO:0032094,ATP metabolic process; adipose tissue development; calcium ion binding; calcium ion transmembrane transport; camera-type eye development; cellular respiration; integral to membrane; mitochondrial inner membrane; mitochondrion; multicellular organism growth; response to activity; response to dietary excess; response to food,PF13499;PF13833;PF00153;,,,,,,,,,SCMC2_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412] comp143169_c0_seq31,2603,39.1856,0.87423365,0,0,,5.00E-15,Q9H0C2,"ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein)","ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein) [Cleaved into: ADP/ATP translocase 4, N-terminally processed]",GO:0005929; GO:0016021; GO:0005743; GO:0005739; GO:0055085; GO:0005215,cilium; integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport; transporter activity,PF00153;,,,,,,,,,ADT4_HUMAN,Homo sapiens (Human),translation [GO:0006412]; transmembrane transport [GO:0055085] comp143169_c0_seq32,2402,39.1757,0.88128004,0,0,,9.00E-115,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq33,2745,39.1985,0.904091,0,0,,3.00E-12,Q0V7M4,Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),GO:0005509; GO:0016021; GO:0005743; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF13499;PF13833;PF00153;,,,,,,,,,SCMC2_BOVIN,Bos taurus (Bovine),adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412] comp143169_c0_seq4,2746,39.2571,0.89195409,0,0,,3.00E-12,Q0V7M4,Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25),GO:0005509; GO:0016021; GO:0005743; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF13499;PF13833;PF00153;,,,,,,,,,SCMC2_BOVIN,Bos taurus (Bovine),adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412] comp143169_c0_seq6,2418,39.1646,0.88673036,0,0,,1.00E-114,O77792,Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9),GO:0016021; GO:0005743; GO:0006839,integral to membrane; mitochondrial inner membrane; mitochondrial transport,PF00153;,,,,,,,,,UCP3_BOVIN,Bos taurus (Bovine),mitochondrial transport [GO:0006839]; translation [GO:0006412] comp143169_c0_seq8,2483,39.3878,0.87567582,0,0,,1.00E-57,O95258,Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14),Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14),GO:0009060; GO:0005887; GO:0005743; GO:0006839; GO:0005739; GO:0006810,aerobic respiration; integral to plasma membrane; mitochondrial inner membrane; mitochondrial transport; mitochondrion; transport,PF00153;,,,,,,,,,UCP5_HUMAN,Homo sapiens (Human),aerobic respiration [GO:0009060]; mitochondrial transport [GO:0006839]; proton transport [GO:0015992]; translation [GO:0006412]; transport [GO:0006810] comp143170_c0_seq1,4583,40.5193,0.41114536,6114,323,,0,Q96MR6,WD repeat-containing protein 65,Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65),,,PF00400;,0,CHOYP_LOC100371909.1.1,,,,,,,WDR65_HUMAN,Homo sapiens (Human), comp143171_c1_seq1,1468,49.1144,0.63818065,0,0,,,,,,,,,3.00E-12,CHOYP_CSPP1.5.14,,,,,,,,, comp143171_c1_seq11,3096,48.4819,0.60185733,0,0,,,,,,,,,8.00E-11,CHOYP_CSPP1.5.14,,,,,,,,, comp143171_c1_seq20,1433,49.0579,0.66719873,0,0,,,,,,,,,4.00E-11,CHOYP_CSPP1.5.14,,,,,,,,, comp143171_c1_seq26,2507,48.5042,0.63386112,0,0,,,,,,,,,6.00E-11,CHOYP_CSPP1.5.14,,,,,,,,, comp143171_c1_seq36,939,46.5389,0.55129718,81,39,,2.00E-09,B2RX88,Centrosome and spindle pole associated protein 1,Centrosome and spindle pole associated protein 1,GO:0005813; GO:0005737; GO:0005874; GO:0032467; GO:0000922,centrosome; cytoplasm; microtubule; positive regulation of cytokinesis; spindle pole,,1.00E-27,CHOYP_CSPP1.9.14,1.00E-37,ruditapes_c15986,,,,,CSPP1_MOUSE,Mus musculus (Mouse),positive regulation of cell division [GO:0051781]; positive regulation of cytokinesis [GO:0032467] comp143173_c1_seq11,961,42.5598,0.8301291,0,0,,,,,,,,,5.00E-39,CHOYP_TRAK1.1.2,,,,,,,,, comp143173_c1_seq2,2876,47.9833,0.67012391,0,0,,1.00E-83,O60296,Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein),Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein),GO:0050811; GO:0005769; GO:0005739; GO:0005634; GO:0005886; GO:0006493; GO:0006605; GO:0006357,GABA receptor binding; early endosome; mitochondrion; nucleus; plasma membrane; protein O-linked glycosylation; protein targeting; regulation of transcription from RNA polymerase II promoter,PF04849;PF12448;,,,,,,,,,TRAK2_HUMAN,Homo sapiens (Human),protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp143173_c1_seq3,2840,48.0986,0.67512954,0,0,,6.00E-80,Q9UPV9,Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein),Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein),GO:0005769; GO:0008333; GO:0005739; GO:0005634; GO:0006493; GO:0006605; GO:0006357,early endosome; endosome to lysosome transport; mitochondrion; nucleus; protein O-linked glycosylation; protein targeting; regulation of transcription from RNA polymerase II promoter,PF04849;PF12448;,,,,,,,,,TRAK1_HUMAN,Homo sapiens (Human),endosome to lysosome transport [GO:0008333]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp143173_c1_seq6,2579,44.7848,0.58366472,7,10,,1.00E-13,O15265,Ataxin-7 (Spinocerebellar ataxia type 7 protein),Ataxin-7 (Spinocerebellar ataxia type 7 protein),GO:0008219; GO:0003682; GO:0005737; GO:0016578; GO:0015630; GO:0000226; GO:0043569; GO:0042326; GO:0016363; GO:0005634; GO:0006997; GO:0045944; GO:0006351; GO:0007601,"cell death; chromatin binding; cytoplasm; histone deubiquitination; microtubule cytoskeleton; microtubule cytoskeleton organization; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of phosphorylation; nuclear matrix; nucleus; nucleus organization; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; visual perception",PF08313;,,,,,,,,,ATX7_HUMAN,Homo sapiens (Human),"histone deubiquitination [GO:0016578]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of phosphorylation [GO:0042326]; nucleus organization [GO:0006997]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp143173_c1_seq7,860,44.0698,0.81674826,0,0,,8.00E-49,Q9UPV9,Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein),Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein),GO:0005769; GO:0008333; GO:0005739; GO:0005634; GO:0006493; GO:0006605; GO:0006357,early endosome; endosome to lysosome transport; mitochondrion; nucleus; protein O-linked glycosylation; protein targeting; regulation of transcription from RNA polymerase II promoter,PF04849;PF12448;,4.00E-39,CHOYP_TRAK1.1.2,,,,,,,TRAK1_HUMAN,Homo sapiens (Human),endosome to lysosome transport [GO:0008333]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp143173_c1_seq8,2456,44.5847,0.57061846,2,0,,6.00E-15,Q9ULK2,Ataxin-7-like protein 1 (Ataxin-7-like protein 4),Ataxin-7-like protein 1 (Ataxin-7-like protein 4),,,PF08313;,7.00E-17,CHOYP_AT7L1.1.1,,,,,,,AT7L1_HUMAN,Homo sapiens (Human), comp143175_c0_seq1,659,43.8543,0.4881668,24,157,,2.00E-33,Q9ZL45,Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75),Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75),GO:0005524; GO:0006777; GO:0016740,ATP binding; Mo-molybdopterin cofactor biosynthetic process; transferase activity,PF00994;,6.00E-23,CHOYP_GEPH.2.2,,,,,,,MOG_HELPJ,Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp143175_c0_seq2,1903,42.6169,0.81681704,313,1991,,3.00E-145,Q9NQX3,Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)],Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)],GO:0005524; GO:0006777; GO:0030054; GO:0005737; GO:0005856; GO:0007529; GO:0046872; GO:0032324; GO:0005886; GO:0045211; GO:0016740; GO:0006767,ATP binding; Mo-molybdopterin cofactor biosynthetic process; cell junction; cytoplasm; cytoskeleton; establishment of synaptic specificity at neuromuscular junction; metal ion binding; molybdopterin cofactor biosynthetic process; plasma membrane; postsynaptic membrane; transferase activity; water-soluble vitamin metabolic process,PF00994;PF03454;PF03453;,3.00E-71,CHOYP_GEPH.1.2,9.00E-56,ruditapes_c21044,,,,,GEPH_HUMAN,Homo sapiens (Human),gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp143176_c1_seq1,2228,38.7792,0.43369518,266,1045,,7.00E-21,Q63505,General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha),GO:0003677; GO:0034735; GO:0006351,"DNA binding; transcription factor TFIIIC2 complex; transcription, DNA-dependent",PF04182;,,,,,,,,,TF3C1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp143178_c1_seq4,1278,35.2895,0.37730121,0,13,,7.00E-08,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,9.00E-12,CHOYP_LOC101171725.3.3,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143184_c0_seq1,1569,46.399,0.67615175,30,0,,1.00E-105,Q6ZMV9,Kinesin-like protein KIF6,Kinesin-like protein KIF6,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,,,,,,,,,KIF6_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp143184_c0_seq2,4188,42.8606,0.59802842,543,18,,2.00E-52,O95239,Chromosome-associated kinesin KIF4A (Chromokinesin-A),Chromosome-associated kinesin KIF4A (Chromokinesin-A),GO:0005524; GO:0003677; GO:0008089; GO:0019886; GO:0007411; GO:0007596; GO:0005694; GO:0005829; GO:0005871; GO:0003777; GO:0030496; GO:0016363; GO:0005634; GO:0006996; GO:0005876,ATP binding; DNA binding; anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; blood coagulation; chromosome; cytosol; kinesin complex; microtubule motor activity; midbody; nuclear matrix; nucleus; organelle organization; spindle microtubule,PF00225;,3.00E-125,CHOYP_LOC100372958.1.1,,,,,,,KIF4A_HUMAN,Homo sapiens (Human),"anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp143187_c0_seq1,4200,32.6429,0.3310213,62,601,,1.00E-15,Q42679,S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],GO:0006557; GO:0004014; GO:0008295; GO:0006597,S-adenosylmethioninamine biosynthetic process; adenosylmethionine decarboxylase activity; spermidine biosynthetic process; spermine biosynthetic process,PF01536;,1.00E-92,CHOYP_LOC100742284.1.1,,,,,,,DCAM_CATRO,Catharanthus roseus (Madagascar periwinkle) (Vinca rosea),S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] comp143187_c0_seq2,3189,33.5528,0.32342878,3,46,,2.00E-54,P91931,S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],GO:0006557; GO:0004014; GO:0050829; GO:0008295; GO:0006597,S-adenosylmethioninamine biosynthetic process; adenosylmethionine decarboxylase activity; defense response to Gram-negative bacterium; spermidine biosynthetic process; spermine biosynthetic process,PF01536;,,,,,,,,,DCAM_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] comp143187_c0_seq3,3612,33.361,0.27894693,0,24,,2.00E-50,P79888,S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],GO:0006557; GO:0004014; GO:0008295; GO:0006597,S-adenosylmethioninamine biosynthetic process; adenosylmethionine decarboxylase activity; spermidine biosynthetic process; spermine biosynthetic process,PF01536;,,,,,,,,,DCAM_XENLA,Xenopus laevis (African clawed frog),S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] comp143187_c0_seq4,4219,32.567,0.3400015,96,604,,5.00E-54,P91931,S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],GO:0006557; GO:0004014; GO:0050829; GO:0008295; GO:0006597,S-adenosylmethioninamine biosynthetic process; adenosylmethionine decarboxylase activity; defense response to Gram-negative bacterium; spermidine biosynthetic process; spermine biosynthetic process,PF01536;,1.00E-92,CHOYP_LOC100742284.1.1,,,,,,,DCAM_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] comp143187_c1_seq1,445,45.618,0.5394101,10,123,,7.00E-42,O02655,S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain],GO:0006557; GO:0004014; GO:0008295; GO:0006597,S-adenosylmethioninamine biosynthetic process; adenosylmethionine decarboxylase activity; spermidine biosynthetic process; spermine biosynthetic process,PF01536;,3.00E-24,CHOYP_LOC100742284.1.1,,,,,,,DCAM_CAEEL,Caenorhabditis elegans,S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] comp143189_c1_seq2,1067,43.1115,0.46466445,17,266,,3.00E-154,O93479,Origin recognition complex subunit 4,Origin recognition complex subunit 4,GO:0005524; GO:0003677; GO:0006260; GO:0005664,ATP binding; DNA binding; DNA replication; nuclear origin of replication recognition complex,PF14629;,7.00E-82,CHOYP_ORC4.1.1,,,,,,,ORC4_XENLA,Xenopus laevis (African clawed frog),DNA replication [GO:0006260] comp143191_c0_seq1,4073,37.6381,0.84069919,8,158,,3.00E-146,Q9GLK0,Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1),Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1),GO:0031424; GO:0016020; GO:0046872; GO:0018149; GO:0003810,keratinization; membrane; metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,TGM1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] comp143191_c0_seq3,3319,39.9819,0.89130593,0,11,,2.00E-101,Q96PF1,Protein-glutamine gamma-glutamyltransferase Z (Transglutaminase Z) (TG(Z)) (TGZ) (TGase Z) (EC 2.3.2.13) (Transglutaminase-7) (TGase-7),Protein-glutamine gamma-glutamyltransferase Z (Transglutaminase Z) (TG(Z)) (TGZ) (TGase Z) (EC 2.3.2.13) (Transglutaminase-7) (TGase-7),GO:0046872; GO:0018149; GO:0003810,metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,9.00E-93,CHOYP_NEMVEDRAFT_V1G97278.1.2,,,,,,,TGM7_HUMAN,Homo sapiens (Human),peptide cross-linking [GO:0018149] comp143191_c0_seq4,4047,37.7811,0.83231742,4,52,,3.00E-146,Q9GLK0,Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1),Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1),GO:0031424; GO:0016020; GO:0046872; GO:0018149; GO:0003810,keratinization; membrane; metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,6.00E-90,CHOYP_NEMVEDRAFT_V1G97278.1.2,,,,,,,TGM1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] comp143192_c2_seq1,1485,35.8923,0.69735527,529,1730,,6.00E-07,Q9U8F1,Cysteine dioxygenase (CDO) (EC 1.13.11.20),Cysteine dioxygenase (CDO) (EC 1.13.11.20),GO:0046439; GO:0017172; GO:0005506; GO:0042412,L-cysteine metabolic process; cysteine dioxygenase activity; iron ion binding; taurine biosynthetic process,PF05995;,,,,,,,,,CDO_SCHJA,Schistosoma japonicum (Blood fluke),taurine biosynthetic process [GO:0042412] comp143192_c2_seq2,527,40.797,0.75093604,17,185,,1.00E-12,Q5RBQ7,Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I),Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I),GO:0046439; GO:0017172; GO:0005829; GO:0005506; GO:0042412,L-cysteine metabolic process; cysteine dioxygenase activity; cytosol; iron ion binding; taurine biosynthetic process,PF05995;,,,,,,,,,CDO1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),taurine biosynthetic process [GO:0042412] comp143193_c0_seq1,1797,36.8392,0.436245,0,0,,,,,,,,,4.00E-107,CHOYP_LOC100702367.1.1,,,,,,,,, comp143193_c0_seq5,1549,38.8638,0.43578516,7,11,,2.00E-111,Q5U3V9,Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22),Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22),GO:0005737; GO:0015031,cytoplasm; protein transport,PF04157;,3.00E-107,CHOYP_LOC100702367.1.1,,,,,,,SNF8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] comp143193_c0_seq6,1812,36.6446,0.43758136,4,35,,3.00E-37,Q12483,Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22) (Vacuolar protein-sorting-associated protein 22),Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22) (Vacuolar protein-sorting-associated protein 22),GO:0000814; GO:0000433; GO:0006623; GO:0043162,ESCRT II complex; negative regulation of transcription from RNA polymerase II promoter by glucose; protein targeting to vacuole; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,PF04157;,,,,,,,,,SNF8_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; protein targeting to vacuole [GO:0006623]; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp143193_c0_seq7,1789,36.6126,0.44535899,0,0,,2.00E-110,Q5U3V9,Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22),Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22),GO:0005737; GO:0015031,cytoplasm; protein transport,PF04157;,,,,,,,,,SNF8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] comp143195_c0_seq1,4005,37.0287,0.27403254,6092,16888,,0,P40939,"Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]","Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]",GO:0003857; GO:0051287; GO:0003985; GO:0035965; GO:0004300; GO:0006635; GO:0000062; GO:0046474; GO:0016509; GO:0016508; GO:0016507; GO:0005743; GO:0042645; GO:0005730; GO:0042493; GO:0032868,3-hydroxyacyl-CoA dehydrogenase activity; NAD binding; acetyl-CoA C-acetyltransferase activity; cardiolipin acyl-chain remodeling; enoyl-CoA hydratase activity; fatty acid beta-oxidation; fatty-acyl-CoA binding; glycerophospholipid biosynthetic process; long-chain-3-hydroxyacyl-CoA dehydrogenase activity; long-chain-enoyl-CoA hydratase activity; mitochondrial fatty acid beta-oxidation multienzyme complex; mitochondrial inner membrane; mitochondrial nucleoid; nucleolus; response to drug; response to insulin stimulus,PF00725;PF02737;PF00378;,1.00E-148,CHOYP_LOC100703423.1.1,2.00E-99,ruditapes_c19790,,,,,ECHA_HUMAN,Homo sapiens (Human),cardiolipin acyl-chain remodeling [GO:0035965]; fatty acid beta-oxidation [GO:0006635]; response to drug [GO:0042493]; response to insulin [GO:0032868] comp143196_c0_seq1,2564,41.5757,0.54180038,1180,6203,,0,P00432,Catalase (EC 1.11.1.6),Catalase (EC 1.11.1.6),GO:0050661; GO:0009650; GO:0009060; GO:0004046; GO:0004096; GO:0008203; GO:0020037; GO:0020027; GO:0042744; GO:0046872; GO:0005739; GO:0032088; GO:0043066; GO:0005778; GO:0051092; GO:0051781; GO:0014068; GO:0051289; GO:0006641,NADP binding; UV protection; aerobic respiration; aminoacylase activity; catalase activity; cholesterol metabolic process; heme binding; hemoglobin metabolic process; hydrogen peroxide catabolic process; metal ion binding; mitochondrion; negative regulation of NF-kappaB transcription factor activity; negative regulation of apoptotic process; peroxisomal membrane; positive regulation of NF-kappaB transcription factor activity; positive regulation of cell division; positive regulation of phosphatidylinositol 3-kinase cascade; protein homotetramerization; triglyceride metabolic process,PF00199;PF06628;,0,CHOYP_CAT.1.1,3.00E-25,ruditapes2_c1441,0,EF687775.p.cg.6,2,,CATA_BOVIN,Bos taurus (Bovine),aerobic respiration [GO:0009060]; cholesterol metabolic process [GO:0008203]; hemoglobin metabolic process [GO:0020027]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of apoptotic process [GO:0043066]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; osteoblast differentiation [GO:0001649]; oxidation-reduction process [GO:0055114]; positive regulation of cell division [GO:0051781]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein homotetramerization [GO:0051289]; response to hydrogen peroxide [GO:0042542]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650] comp143197_c0_seq1,3791,33.0256,0.67473314,8,18,,2.00E-136,P51876,Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein),Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein),GO:0005525; GO:0003924; GO:0007188; GO:0046872; GO:0004871,GTP binding; GTPase activity; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; metal ion binding; signal transducer activity,PF00503;,4.00E-16,CHOYP_GNAQ.1.1,,,,,,,GNAI_HELTI,Planorbella trivolvis (Marsh rams-horn) (Helisoma trivolvis),adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188] comp143197_c0_seq2,3810,33.0971,0.66826011,22,31,,2.00E-136,P51876,Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein),Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein),GO:0005525; GO:0003924; GO:0007188; GO:0046872; GO:0004871,GTP binding; GTPase activity; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; metal ion binding; signal transducer activity,PF00503;,5.00E-160,CHOYP_GNAI.1.1,,,,,,,GNAI_HELTI,Planorbella trivolvis (Marsh rams-horn) (Helisoma trivolvis),adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188] comp143198_c1_seq2,1221,46.1097,0.39941977,0,7,,2.00E-28,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,4.00E-104,CHOYP_BRAFLDRAFT_60329.1.1,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp143198_c1_seq4,1754,48.2326,0.38671033,143,254,,0,P54319,Phospholipase A-2-activating protein (PLA2P) (PLAP),Phospholipase A-2-activating protein (PLA2P) (PLAP),GO:0070062; GO:0006954; GO:0016005,extracellular vesicular exosome; inflammatory response; phospholipase A2 activator activity,PF09070;PF08324;PF00400;,,,,,,,,,PLAP_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954] comp143201_c1_seq1,3587,44.9958,0.55005711,25,0,,2.00E-14,Q2H679,"ATP-dependent RNA helicase MRH4, mitochondrial (EC 3.6.4.13)","ATP-dependent RNA helicase MRH4, mitochondrial (EC 3.6.4.13)",GO:0005524; GO:0008026; GO:0003723; GO:0005739,ATP binding; ATP-dependent helicase activity; RNA binding; mitochondrion,PF00270;PF00271;,0,CHOYP_DDX3Y.1.1,,,,,,,MRH4_CHAGB,Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus), comp143201_c1_seq11,221,41.629,0.83973351,15,89,,,,,,,,,5.00E-12,CHOYP_contig_028878,,,,,,,,, comp143201_c1_seq12,2374,41.2805,0.55024105,0,7,,1.00E-43,Q0UAT0,ATP-dependent RNA helicase FAL1 (EC 3.6.4.13),ATP-dependent RNA helicase FAL1 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF00271;,,,,,,,,,FAL1_PHANO,Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum),regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] comp143201_c1_seq13,3607,44.8572,0.56148724,0,0,,2.00E-72,Q65N62,DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13),GO:0005524; GO:0004004; GO:0003723; GO:0043590; GO:0005737,ATP binding; ATP-dependent RNA helicase activity; RNA binding; bacterial nucleoid; cytoplasm,PF00270;PF00271;,,,,,,,,,CSHA_BACLD,Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46),RNA catabolic process [GO:0006401]; RNA secondary structure unwinding [GO:0010501] comp143201_c1_seq14,388,31.9588,0.4048947,9,1,,,,,,,,,1.00E-17,CHOYP_contig_029127,,,,,,,,, comp143201_c1_seq15,3415,44.0703,0.56673736,0,0,,0,O00571,"ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)","ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)",GO:0005524; GO:0004003; GO:0004004; GO:0003677; GO:0010501; GO:0035613; GO:0071243; GO:0071470; GO:0007059; GO:0010494; GO:0008190; GO:0008625; GO:0045087; GO:0007243; GO:0097193; GO:0048027; GO:0042256; GO:0005741; GO:0019048; GO:0043066; GO:0030308; GO:0043154; GO:2001243; GO:0031333; GO:0017148; GO:0016607; GO:0005634; GO:0008143; GO:1900087; GO:0043065; GO:0030307; GO:0071651; GO:0043280; GO:0032728; GO:0045944; GO:0045948; GO:0009615; GO:0043024; GO:0034063; GO:0008134; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; ATP-dependent RNA helicase activity; DNA binding; RNA secondary structure unwinding; RNA stem-loop binding; cellular response to arsenic-containing substance; cellular response to osmotic stress; chromosome segregation; cytoplasmic stress granule; eukaryotic initiation factor 4E binding; extrinsic apoptotic signaling pathway via death domain receptors; innate immune response; intracellular protein kinase cascade; intrinsic apoptotic signaling pathway; mRNA 5'-UTR binding; mature ribosome assembly; mitochondrial outer membrane; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of cell growth; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of protein complex assembly; negative regulation of translation; nuclear speck; nucleus; poly(A) RNA binding; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of apoptotic process; positive regulation of cell growth; positive regulation of chemokine (C-C motif) ligand 5 production; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interferon-beta production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translational initiation; response to virus; ribosomal small subunit binding; stress granule assembly; transcription factor binding; transcription, DNA-dependent",PF00270;PF00271;,0,CHOYP_DDX3Y.1.1,,,,,,,DDX3X_HUMAN,Homo sapiens (Human),"cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp143201_c1_seq16,3365,44.5765,0.56702113,0,0,,0,O00571,"ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)","ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)",GO:0005524; GO:0004003; GO:0004004; GO:0003677; GO:0010501; GO:0035613; GO:0071243; GO:0071470; GO:0007059; GO:0010494; GO:0008190; GO:0008625; GO:0045087; GO:0007243; GO:0097193; GO:0048027; GO:0042256; GO:0005741; GO:0019048; GO:0043066; GO:0030308; GO:0043154; GO:2001243; GO:0031333; GO:0017148; GO:0016607; GO:0005634; GO:0008143; GO:1900087; GO:0043065; GO:0030307; GO:0071651; GO:0043280; GO:0032728; GO:0045944; GO:0045948; GO:0009615; GO:0043024; GO:0034063; GO:0008134; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; ATP-dependent RNA helicase activity; DNA binding; RNA secondary structure unwinding; RNA stem-loop binding; cellular response to arsenic-containing substance; cellular response to osmotic stress; chromosome segregation; cytoplasmic stress granule; eukaryotic initiation factor 4E binding; extrinsic apoptotic signaling pathway via death domain receptors; innate immune response; intracellular protein kinase cascade; intrinsic apoptotic signaling pathway; mRNA 5'-UTR binding; mature ribosome assembly; mitochondrial outer membrane; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of cell growth; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of protein complex assembly; negative regulation of translation; nuclear speck; nucleus; poly(A) RNA binding; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of apoptotic process; positive regulation of cell growth; positive regulation of chemokine (C-C motif) ligand 5 production; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interferon-beta production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translational initiation; response to virus; ribosomal small subunit binding; stress granule assembly; transcription factor binding; transcription, DNA-dependent",PF00270;PF00271;,4.00E-15,CHOYP_LOC100562697.1.1,,,,,,,DDX3X_HUMAN,Homo sapiens (Human),"cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp143201_c1_seq17,301,44.186,0.34585815,8,9,,,,,,,,,1.00E-15,CHOYP_contig_046688,,,,,,,,, comp143201_c1_seq18,272,41.5441,0.4284427,0,16,,,,,,,,,8.00E-17,CHOYP_contig_054187,,,,,,,,, comp143201_c1_seq2,3518,44.9403,0.56185051,0,0,,1.00E-51,Q7XMK8,DEAD-box ATP-dependent RNA helicase 6 (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase 6 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0000932; GO:0006397; GO:0051028; GO:0006417,ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasmic mRNA processing body; mRNA processing; mRNA transport; regulation of translation,PF00270;PF00271;,,,,,,,,,RH6_ORYSJ,Oryza sativa subsp. japonica (Rice),cytoplasmic mRNA processing body assembly [GO:0033962]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501] comp143201_c1_seq3,3395,44.2121,0.554275,2,23,,0,O00571,"ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)","ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)",GO:0005524; GO:0004003; GO:0004004; GO:0003677; GO:0010501; GO:0035613; GO:0071243; GO:0071470; GO:0007059; GO:0010494; GO:0008190; GO:0008625; GO:0045087; GO:0007243; GO:0097193; GO:0048027; GO:0042256; GO:0005741; GO:0019048; GO:0043066; GO:0030308; GO:0043154; GO:2001243; GO:0031333; GO:0017148; GO:0016607; GO:0005634; GO:0008143; GO:1900087; GO:0043065; GO:0030307; GO:0071651; GO:0043280; GO:0032728; GO:0045944; GO:0045948; GO:0009615; GO:0043024; GO:0034063; GO:0008134; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; ATP-dependent RNA helicase activity; DNA binding; RNA secondary structure unwinding; RNA stem-loop binding; cellular response to arsenic-containing substance; cellular response to osmotic stress; chromosome segregation; cytoplasmic stress granule; eukaryotic initiation factor 4E binding; extrinsic apoptotic signaling pathway via death domain receptors; innate immune response; intracellular protein kinase cascade; intrinsic apoptotic signaling pathway; mRNA 5'-UTR binding; mature ribosome assembly; mitochondrial outer membrane; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of cell growth; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of protein complex assembly; negative regulation of translation; nuclear speck; nucleus; poly(A) RNA binding; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of apoptotic process; positive regulation of cell growth; positive regulation of chemokine (C-C motif) ligand 5 production; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interferon-beta production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translational initiation; response to virus; ribosomal small subunit binding; stress granule assembly; transcription factor binding; transcription, DNA-dependent",PF00270;PF00271;,0,CHOYP_DDX3Y.1.1,,,,,,,DDX3X_HUMAN,Homo sapiens (Human),"cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp143201_c1_seq4,3367,44.1342,0.55458288,0,0,,6.00E-80,A5E1W4,ATP-dependent RNA helicase DBP3 (EC 3.6.4.13),ATP-dependent RNA helicase DBP3 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF00271;,,,,,,,,,DBP3_LODEL,Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus),"endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000464]; ribosomal large subunit assembly [GO:0000027]" comp143201_c1_seq8,209,43.5407,0.60929828,0,11,,,,,,,,,2.00E-16,CHOYP_contig_054187,,,,,,,,, comp143201_c1_seq9,3317,44.6488,0.55498213,0,0,,0,O00571,"ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)","ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)",GO:0005524; GO:0004003; GO:0004004; GO:0003677; GO:0010501; GO:0035613; GO:0071243; GO:0071470; GO:0007059; GO:0010494; GO:0008190; GO:0008625; GO:0045087; GO:0007243; GO:0097193; GO:0048027; GO:0042256; GO:0005741; GO:0019048; GO:0043066; GO:0030308; GO:0043154; GO:2001243; GO:0031333; GO:0017148; GO:0016607; GO:0005634; GO:0008143; GO:1900087; GO:0043065; GO:0030307; GO:0071651; GO:0043280; GO:0032728; GO:0045944; GO:0045948; GO:0009615; GO:0043024; GO:0034063; GO:0008134; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; ATP-dependent RNA helicase activity; DNA binding; RNA secondary structure unwinding; RNA stem-loop binding; cellular response to arsenic-containing substance; cellular response to osmotic stress; chromosome segregation; cytoplasmic stress granule; eukaryotic initiation factor 4E binding; extrinsic apoptotic signaling pathway via death domain receptors; innate immune response; intracellular protein kinase cascade; intrinsic apoptotic signaling pathway; mRNA 5'-UTR binding; mature ribosome assembly; mitochondrial outer membrane; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; negative regulation of cell growth; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of protein complex assembly; negative regulation of translation; nuclear speck; nucleus; poly(A) RNA binding; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of apoptotic process; positive regulation of cell growth; positive regulation of chemokine (C-C motif) ligand 5 production; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interferon-beta production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translational initiation; response to virus; ribosomal small subunit binding; stress granule assembly; transcription factor binding; transcription, DNA-dependent",PF00270;PF00271;,0,CHOYP_DDX3Y.1.1,,,,,,,DDX3X_HUMAN,Homo sapiens (Human),"cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp143202_c0_seq1,1405,35.9431,0.51375852,2221,7753,,9.00E-124,P15650,"Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)","Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)",GO:0033539; GO:0000062; GO:0050660; GO:0042758; GO:0004466; GO:0005759; GO:0031966; GO:0051289,fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty-acyl-CoA binding; flavin adenine dinucleotide binding; long-chain fatty acid catabolic process; long-chain-acyl-CoA dehydrogenase activity; mitochondrial matrix; mitochondrial membrane; protein homotetramerization,PF00441;PF02770;PF02771;,6.00E-122,CHOYP_ACADL.1.1,,,,,,,ACADL_RAT,Rattus norvegicus (Rat),"carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; long-chain fatty acid catabolic process [GO:0042758]; protein homotetramerization [GO:0051289]" comp143202_c1_seq1,696,45.6897,0.51587278,650,2091,,5.00E-26,Q9VSA3,"Probable medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)","Probable medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)",GO:0003995; GO:0006635; GO:0050660; GO:0005811; GO:0005875; GO:0005759; GO:0005739,acyl-CoA dehydrogenase activity; fatty acid beta-oxidation; flavin adenine dinucleotide binding; lipid particle; microtubule associated complex; mitochondrial matrix; mitochondrion,PF00441;PF02770;PF02771;,,,,,,,,,ACADM_DROME,Drosophila melanogaster (Fruit fly),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp143203_c0_seq1,1862,37.1643,0.40509496,78,392,,5.00E-37,Q9CYI0,Protein Njmu-R1,Protein Njmu-R1,,,PF15053;,1.00E-17,CHOYP_LOC592013.1.1,,,,,,,NJMU_MOUSE,Mus musculus (Mouse), comp143203_c0_seq3,1649,37.5985,0.41213953,3,53,,,,,,,,,7.00E-15,CHOYP_LOC592013.1.1,,,,,,,,, comp143204_c0_seq1,709,39.6333,0.29338901,34,220,,4.00E-58,O95352,Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein),Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein),GO:0019778; GO:0007628; GO:0006914; GO:0055013; GO:0006520; GO:0021955; GO:0021680; GO:0021987; GO:0005737; GO:0001889; GO:0061025; GO:0043066; GO:0050877; GO:0006996; GO:0016239; GO:0031401; GO:0009791; GO:0000407; GO:0030163; GO:0042803; GO:0006497; GO:0032446; GO:0015031; GO:0021860; GO:0031396; GO:0042594; GO:0004839,APG12 activating enzyme activity; adult walking behavior; autophagy; cardiac muscle cell development; cellular amino acid metabolic process; central nervous system neuron axonogenesis; cerebellar Purkinje cell layer development; cerebral cortex development; cytoplasm; liver development; membrane fusion; negative regulation of apoptotic process; neurological system process; organelle organization; positive regulation of macroautophagy; positive regulation of protein modification process; post-embryonic development; pre-autophagosomal structure; protein catabolic process; protein homodimerization activity; protein lipidation; protein modification by small protein conjugation; protein transport; pyramidal neuron development; regulation of protein ubiquitination; response to starvation; ubiquitin activating enzyme activity,PF16420;PF00899;,,,,,,,,,ATG7_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; cellular response to hyperoxia [GO:0071455]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; C-terminal protein lipidation [GO:0006501]; defense response to virus [GO:0051607]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of nucleus [GO:0034727]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein transport [GO:0015031]; regulation of mitophagy [GO:1903146]; suppression by virus of host autophagy [GO:0039521] comp143204_c3_seq1,763,44.692,0.34717621,83,625,,2.00E-101,O95352,Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein),Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein),GO:0019778; GO:0007628; GO:0006914; GO:0055013; GO:0006520; GO:0021955; GO:0021680; GO:0021987; GO:0005737; GO:0001889; GO:0061025; GO:0043066; GO:0050877; GO:0006996; GO:0016239; GO:0031401; GO:0009791; GO:0000407; GO:0030163; GO:0042803; GO:0006497; GO:0032446; GO:0015031; GO:0021860; GO:0031396; GO:0042594; GO:0004839,APG12 activating enzyme activity; adult walking behavior; autophagy; cardiac muscle cell development; cellular amino acid metabolic process; central nervous system neuron axonogenesis; cerebellar Purkinje cell layer development; cerebral cortex development; cytoplasm; liver development; membrane fusion; negative regulation of apoptotic process; neurological system process; organelle organization; positive regulation of macroautophagy; positive regulation of protein modification process; post-embryonic development; pre-autophagosomal structure; protein catabolic process; protein homodimerization activity; protein lipidation; protein modification by small protein conjugation; protein transport; pyramidal neuron development; regulation of protein ubiquitination; response to starvation; ubiquitin activating enzyme activity,PF16420;PF00899;,1.00E-84,CHOYP_ATG7.1.1,,,,,,,ATG7_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; cellular response to hyperoxia [GO:0071455]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; C-terminal protein lipidation [GO:0006501]; defense response to virus [GO:0051607]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of nucleus [GO:0034727]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein transport [GO:0015031]; regulation of mitophagy [GO:1903146]; suppression by virus of host autophagy [GO:0039521] comp143207_c0_seq1,1187,42.0388,0.76714506,57,111,,1.00E-104,Q3ZCH9,Haloacid dehalogenase-like hydrolase domain-containing protein 2,Haloacid dehalogenase-like hydrolase domain-containing protein 2,GO:0046872,metal ion binding,PF13344;,,,,,,,,,HDHD2_BOVIN,Bos taurus (Bovine),dephosphorylation [GO:0016311] comp143207_c0_seq2,1239,41.4044,0.81379784,55,143,,1.00E-104,Q3ZCH9,Haloacid dehalogenase-like hydrolase domain-containing protein 2,Haloacid dehalogenase-like hydrolase domain-containing protein 2,GO:0046872,metal ion binding,PF13344;,5.00E-15,CHOYP_HDHD2.1.1,,,,,,,HDHD2_BOVIN,Bos taurus (Bovine),dephosphorylation [GO:0016311] comp143207_c0_seq3,1193,42.1626,0.81611884,6,31,,2.00E-12,Q8CHP8,Phosphoglycolate phosphatase (PGP) (PGPase) (EC 3.1.3.18),Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP),GO:0005975; GO:0016311; GO:0008967,carbohydrate metabolic process; dephosphorylation; phosphoglycolate phosphatase activity,PF13344;,,,,,,,,,PGP_MOUSE,Mus musculus (Mouse),dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335] comp143207_c0_seq4,1138,43.2337,0.81470886,0,0,,3.00E-13,Q49W68,Protein NagD homolog,Acid sugar phosphatase (EC 3.1.3.-),,,PF13344;,,,,,,,,,NAGD_STAS1,Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229), comp143208_c0_seq1,935,42.246,0.58490928,78,61,,4.00E-18,Q3UPF5,Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13),Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13),GO:0017151; GO:0005794; GO:0003950; GO:0003723; GO:0071360; GO:0005737; GO:0051607; GO:0045087; GO:0046872; GO:0045071; GO:0005634; GO:0005886; GO:0032781; GO:0043123; GO:1900246; GO:0032727; GO:0032728; GO:0061014; GO:0032481; GO:0009615,DEAD/H-box RNA helicase binding; Golgi apparatus; NAD+ ADP-ribosyltransferase activity; RNA binding; cellular response to exogenous dsRNA; cytoplasm; defense response to virus; innate immune response; metal ion binding; negative regulation of viral genome replication; nucleus; plasma membrane; positive regulation of ATPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of RIG-I signaling pathway; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of mRNA catabolic process; positive regulation of type I interferon production; response to virus,PF00644;PF02825;,,,,,,,,,ZCCHV_MOUSE,Mus musculus (Mouse),cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of ATPase activity [GO:0032781]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]; suppression by virus of host molecular function [GO:0039507] comp143208_c2_seq1,843,43.535,0.72732778,56,59,,2.00E-30,Q8BZ20,Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),GO:0003950; GO:0046872; GO:0005634,NAD+ ADP-ribosyltransferase activity; metal ion binding; nucleus,PF00644;PF02825;PF00642;,,,,,,,,,PAR12_MOUSE,Mus musculus (Mouse), comp143211_c0_seq2,313,32.5879,0.24181995,12,32,,,,,,,,,4.00E-15,CHOYP_contig_019843,,,,,,,,, comp143211_c2_seq1,4982,41.1281,0.66360561,3661,229,,3.00E-61,Q8IV35,WD repeat-containing protein 49,WD repeat-containing protein 49,,,PF00400;,3.00E-164,CHOYP_LOC100368844.1.1,4.00E-90,ruditapes_c15632,,,,,WDR49_HUMAN,Homo sapiens (Human), comp143212_c0_seq1,2420,45,0.52024745,1075,203,,0,Q0V9S9,Coiled-coil domain-containing protein lobo homolog (Coiled-coil domain-containing protein 135),Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog),GO:0030154; GO:0001539; GO:0005929; GO:0007283,cell differentiation; ciliary or bacterial-type flagellar motility; cilium; spermatogenesis,,0,CHOYP_LOC100366728.1.1,,,,,,,CC135_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143213_c1_seq1,5461,47.3357,0.40563796,0,0,,0,O75592,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,0,CHOYP_MYCB2.1.2,,,,,,,MYCB2_HUMAN,Homo sapiens (Human),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143213_c1_seq10,2291,46.5735,0.33396237,0,0,,7.00E-09,Q92834,X-linked retinitis pigmentosa GTPase regulator,X-linked retinitis pigmentosa GTPase regulator,GO:0005794; GO:0005813; GO:0042384; GO:0035085; GO:0036064; GO:0042462; GO:0005085; GO:0006886; GO:0042073; GO:0001750; GO:0050896; GO:0036126; GO:0007601,Golgi apparatus; centrosome; cilium assembly; cilium axoneme; cilium basal body; eye photoreceptor cell development; guanyl-nucleotide exchange factor activity; intracellular protein transport; intraflagellar transport; photoreceptor outer segment; response to stimulus; sperm flagellum; visual perception,PF00415;,,,,,,,,,RPGR_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp143213_c1_seq2,3555,46.5541,0.34474018,0,0,,7.00E-120,Q9NB71,E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1),E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1),GO:0030509; GO:0007628; GO:0006914; GO:0016023; GO:0040011; GO:0030514; GO:0045886; GO:0005634; GO:0005886; GO:0050808; GO:0006351; GO:0004842; GO:0008270,"BMP signaling pathway; adult walking behavior; autophagy; cytoplasmic membrane-bounded vesicle; locomotion; negative regulation of BMP signaling pathway; negative regulation of synaptic growth at neuromuscular junction; nucleus; plasma membrane; synapse organization; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF08005;PF00415;,,,,,,,,,HIW_DROME,Drosophila melanogaster (Fruit fly),"adult walking behavior [GO:0007628]; autophagy [GO:0006914]; BMP signaling pathway [GO:0030509]; locomotion [GO:0040011]; long-term memory [GO:0007616]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; response to axon injury [GO:0048678]; synapse organization [GO:0050808]; transcription, DNA-templated [GO:0006351]" comp143213_c1_seq3,2387,46.7114,0.31808197,0,0,,7.00E-09,Q92834,X-linked retinitis pigmentosa GTPase regulator,X-linked retinitis pigmentosa GTPase regulator,GO:0005794; GO:0005813; GO:0042384; GO:0035085; GO:0036064; GO:0042462; GO:0005085; GO:0006886; GO:0042073; GO:0001750; GO:0050896; GO:0036126; GO:0007601,Golgi apparatus; centrosome; cilium assembly; cilium axoneme; cilium basal body; eye photoreceptor cell development; guanyl-nucleotide exchange factor activity; intracellular protein transport; intraflagellar transport; photoreceptor outer segment; response to stimulus; sperm flagellum; visual perception,PF00415;,,,,,,,,,RPGR_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp143213_c1_seq4,2316,46.4162,0.35338983,0,0,,0,O75592,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,0,CHOYP_MYCB2.1.2,,,,,,,MYCB2_HUMAN,Homo sapiens (Human),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143213_c1_seq5,3459,46.4585,0.35596373,0,0,,4.00E-150,Q9NB71,E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1),E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1),GO:0030509; GO:0007628; GO:0006914; GO:0016023; GO:0040011; GO:0030514; GO:0045886; GO:0005634; GO:0005886; GO:0050808; GO:0006351; GO:0004842; GO:0008270,"BMP signaling pathway; adult walking behavior; autophagy; cytoplasmic membrane-bounded vesicle; locomotion; negative regulation of BMP signaling pathway; negative regulation of synaptic growth at neuromuscular junction; nucleus; plasma membrane; synapse organization; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF08005;PF00415;,7.00E-31,CHOYP_MYCBP2.1.1,,,,,,,HIW_DROME,Drosophila melanogaster (Fruit fly),"adult walking behavior [GO:0007628]; autophagy [GO:0006914]; BMP signaling pathway [GO:0030509]; locomotion [GO:0040011]; long-term memory [GO:0007616]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; response to axon injury [GO:0048678]; synapse organization [GO:0050808]; transcription, DNA-templated [GO:0006351]" comp143213_c1_seq9,6058,47.4579,0.40203877,7,5,,0,O75592,Probable E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc),GO:0030424; GO:0021785; GO:0021952; GO:0015630; GO:0005634; GO:0051493; GO:0032880; GO:0006355; GO:0006351; GO:0004842; GO:0008270,"axon; branchiomotor neuron axon guidance; central nervous system projection neuron axonogenesis; microtubule cytoskeleton; nucleus; regulation of cytoskeleton organization; regulation of protein localization; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;,0,CHOYP_MYCB2.1.2,,,,,,,MYCB2_HUMAN,Homo sapiens (Human),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143214_c0_seq27,456,44.7368,0.21962812,0,0,,2.00E-22,Q6P4J8,WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog),WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog),GO:0005737; GO:0005634,cytoplasm; nucleus,PF12894;PF00400;,,,,,,,,,SMU1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143214_c0_seq4,395,41.2658,0.18248965,9,5,,7.00E-23,Q6NRT3,WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog),WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,1.00E-17,CHOYP_SMU1.1.1,,,,,,,SMU1_XENLA,Xenopus laevis (African clawed frog), comp143214_c0_seq9,944,35.2754,0.4795221,4,8,,,,,,,,,2.00E-17,CHOYP_SMU1.1.1,,,,,,,,, comp143216_c1_seq1,2894,33.2066,0.5017549,50,402,,1.00E-88,Q13257,Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1),Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1),GO:0031145; GO:0051301; GO:0000777; GO:0005829; GO:0000776; GO:0000070; GO:0072686; GO:0007094; GO:0043066; GO:0060564; GO:0005634; GO:0048471; GO:0090267; GO:0000922,anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; condensed chromosome kinetochore; cytosol; kinetochore; mitotic sister chromatid segregation; mitotic spindle; mitotic spindle assembly checkpoint; negative regulation of apoptotic process; negative regulation of mitotic anaphase-promoting complex activity; nucleus; perinuclear region of cytoplasm; positive regulation of mitotic cell cycle spindle assembly checkpoint; spindle pole,PF02301;,1.00E-83,CHOYP_MAD2L1.1.1,,,,,,,MD2L1_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062] comp143216_c1_seq10,1253,30.407,0.41675002,0,0,,,,,,,,,7.00E-13,CHOYP_contig_028791,,,,,,,,, comp143216_c1_seq12,1484,31.1321,0.69703943,0,0,,,,,,,,,4.00E-11,CHOYP_contig_022482,,,,,,,,, comp143216_c1_seq14,1122,30.2139,0.39128951,0,0,,,,,,,,,1.00E-10,CHOYP_LOC583575.1.1,,,,,,,,, comp143216_c1_seq16,1243,31.6975,0.6732994,0,0,,,,,,,,,3.00E-17,CHOYP_contig_037248,,,,,,,,, comp143216_c1_seq17,1275,31.6078,0.66016301,0,0,,,,,,,,,4.00E-16,CHOYP_contig_054043,,,,,,,,, comp143216_c1_seq20,1342,31.8182,0.67929753,0,0,,,,,,,,,4.00E-17,CHOYP_contig_037248,,,,,,,,, comp143216_c1_seq4,1374,31.7322,0.66715222,0,0,,,,,,,,,1.00E-16,CHOYP_contig_033405,,,,,,,,, comp143216_c1_seq8,3229,34.4069,0.50305002,0,0,,4.00E-88,Q13257,Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1),Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1),GO:0031145; GO:0051301; GO:0000777; GO:0005829; GO:0000776; GO:0000070; GO:0072686; GO:0007094; GO:0043066; GO:0060564; GO:0005634; GO:0048471; GO:0090267; GO:0000922,anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; condensed chromosome kinetochore; cytosol; kinetochore; mitotic sister chromatid segregation; mitotic spindle; mitotic spindle assembly checkpoint; negative regulation of apoptotic process; negative regulation of mitotic anaphase-promoting complex activity; nucleus; perinuclear region of cytoplasm; positive regulation of mitotic cell cycle spindle assembly checkpoint; spindle pole,PF02301;,1.00E-83,CHOYP_MAD2L1.1.1,,,2.00E-67,AM864974.p.cg.6,8,,MD2L1_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062] comp143216_c1_seq9,1221,30.4668,0.42594504,0,0,,,,,,,,,7.00E-13,CHOYP_contig_028791,,,,,,,,, comp143217_c1_seq11,406,49.5074,0.68791429,23,13,,4.00E-49,Q8I8U7,Transcription-associated protein 1 (dTRA1),Transcription-associated protein 1 (dTRA1),GO:0035267; GO:0000124; GO:0005737; GO:0016573; GO:0043486; GO:0005875; GO:0006909; GO:0016773; GO:0005703; GO:0045747; GO:0006355; GO:0006351; GO:0035222,"NuA4 histone acetyltransferase complex; SAGA complex; cytoplasm; histone acetylation; histone exchange; microtubule associated complex; phagocytosis; phosphotransferase activity, alcohol group as acceptor; polytene chromosome puff; positive regulation of Notch signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; wing disc pattern formation",PF02259;PF02260;PF00454;,5.00E-72,CHOYP_LOC100123553.1.1,,,,,,,TRA1_DROME,Drosophila melanogaster (Fruit fly),"DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H3 acetylation [GO:0043966]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]" comp143217_c1_seq5,315,45.0794,0.25199616,17,0,,,,,,,,,4.00E-28,CHOYP_TRRAP.2.2,,,,,,,,, comp143217_c1_seq8,391,41.1765,0.36533324,4,0,,,,,,,,,5.00E-28,CHOYP_LOC100123553.1.1,,,,,,,,, comp143218_c0_seq2,923,41.2784,0.59389741,63,258,,2.00E-12,Q8BMQ2,General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta),General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta),GO:0003677; GO:0016573; GO:0004402; GO:0000127; GO:0006351,"DNA binding; histone acetylation; histone acetyltransferase activity; transcription factor TFIIIC complex; transcription, DNA-dependent",PF12657;PF12660;,,,,,,,,,TF3C4_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp143220_c2_seq1,1826,44.7426,0.76665331,6,7,,0,B1WAP7,Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3),Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3),GO:0016055; GO:0008013; GO:0042384; GO:0005737; GO:0035556; GO:0032053; GO:0007275; GO:0004871,Wnt receptor signaling pathway; beta-catenin binding; cilium assembly; cytoplasm; intracellular signal transduction; microtubule basal body organization; multicellular organismal development; signal transducer activity,PF00610;PF02377;PF00778;PF12316;PF00595;,0,CHOYP_DVL.2.2,,,,,,,DVL3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),canonical Wnt signaling pathway [GO:0060070]; ciliary basal body organization [GO:0032053]; cilium assembly [GO:0042384]; intracellular signal transduction [GO:0035556]; planar cell polarity pathway involved in neural tube closure [GO:0090179] comp143220_c2_seq2,1844,44.7939,0.75761598,4,26,,2.00E-174,O14641,Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2),Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2),GO:0045177; GO:0044340; GO:0005938; GO:0021535; GO:0034613; GO:0030136; GO:0090103; GO:0060026; GO:0022007; GO:0005829; GO:0035329; GO:0001843; GO:0005634; GO:0003151; GO:0090179; GO:0005886; GO:0043507; GO:0090263; GO:0061098; GO:0051091; GO:0045893; GO:0007379; GO:0004871; GO:0006366,"apical part of cell; canonical Wnt receptor signaling pathway involved in regulation of cell proliferation; cell cortex; cell migration in hindbrain; cellular protein localization; clathrin-coated vesicle; cochlea morphogenesis; convergent extension; convergent extension involved in neural plate elongation; cytosol; hippo signaling cascade; neural tube closure; nucleus; outflow tract morphogenesis; planar cell polarity pathway involved in neural tube closure; plasma membrane; positive regulation of JUN kinase activity; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein tyrosine kinase activity; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription, DNA-dependent; segment specification; signal transducer activity; transcription from RNA polymerase II promoter",PF00610;PF02377;PF00778;PF12316;PF00595;,8.00E-21,CHOYP_TSP_08621.1.1,,,,,,,DVL2_HUMAN,Homo sapiens (Human),"beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; convergent extension involved in neural plate elongation [GO:0022007]; heart development [GO:0007507]; hippo signaling [GO:0035329]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; protein oligomerization [GO:0051259]; segment specification [GO:0007379]; transcription from RNA polymerase II promoter [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp143220_c2_seq4,464,46.9828,0.54205775,0,18,,,,,,,,,7.00E-27,CHOYP_DVL.2.2,,,,,,,,, comp143226_c0_seq1,3014,39.3165,0.45850691,1,23,,0,Q9C102,Putative glutamate synthase [NADPH] (EC 1.4.1.13) (NADPH-GOGAT),Putative glutamate synthase [NADPH] (EC 1.4.1.13) (NADPH-GOGAT),GO:0051538; GO:0010181; GO:0097054; GO:0005829; GO:0050660; GO:0016040; GO:0004355; GO:0006541; GO:0005506; GO:0005739,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; cytosol; flavin adenine dinucleotide binding; glutamate synthase (NADH) activity; glutamate synthase (NADPH) activity; glutamine metabolic process; iron ion binding; mitochondrion",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,,,,,,,,,GLT1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054] comp143226_c0_seq2,2963,39.1158,0.48001619,6,27,,4.00E-162,O34399,Glutamate synthase [NADPH] small chain (EC 1.4.1.13) (NADPH-GOGAT),Glutamate synthase [NADPH] small chain (EC 1.4.1.13) (NADPH-GOGAT),GO:0097054; GO:0050660; GO:0004355; GO:0051536,L-glutamate biosynthetic process; flavin adenine dinucleotide binding; glutamate synthase (NADPH) activity; iron-sulfur cluster binding,PF14691;PF07992;,0,CHOYP_BRAFLDRAFT_129259.1.1,4.00E-24,ruditapes_c29098,,,,,GLTB_BACSU,Bacillus subtilis (strain 168),L-glutamate biosynthetic process [GO:0097054] comp143226_c0_seq5,1086,45.9484,0.54797262,0,0,,1.00E-08,O33064,Probable ferredoxin/ferredoxin--NADP reductase (FNR) (EC 1.18.1.2),Probable ferredoxin/ferredoxin--NADP reductase (FNR) (EC 1.18.1.2),GO:0051539; GO:0004324; GO:0046872,"4 iron, 4 sulfur cluster binding; ferredoxin-NADP+ reductase activity; metal ion binding",PF00037;PF07992;,,,,,,,,,FPRB_MYCLE,Mycobacterium leprae (strain TN), comp143226_c1_seq1,1824,46.5461,0.37554886,27,18,,0,Q9C102,Putative glutamate synthase [NADPH] (EC 1.4.1.13) (NADPH-GOGAT),Putative glutamate synthase [NADPH] (EC 1.4.1.13) (NADPH-GOGAT),GO:0051538; GO:0010181; GO:0097054; GO:0005829; GO:0050660; GO:0016040; GO:0004355; GO:0006541; GO:0005506; GO:0005739,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; cytosol; flavin adenine dinucleotide binding; glutamate synthase (NADH) activity; glutamate synthase (NADPH) activity; glutamine metabolic process; iron ion binding; mitochondrion",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,,,,,,,,,GLT1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054] comp143226_c1_seq3,1036,44.5946,0.26127512,0,6,,4.00E-43,Q58746,Archaeal glutamate synthase [NADPH] (EC 1.4.1.13) (Archaeal NADPH-GOGAT),Archaeal glutamate synthase [NADPH] (EC 1.4.1.13) (Archaeal NADPH-GOGAT),GO:0051539; GO:0006537; GO:0004355; GO:0046872,"4 iron, 4 sulfur cluster binding; glutamate biosynthetic process; glutamate synthase (NADPH) activity; metal ion binding",PF01645;,2.00E-157,CHOYP_BRAFLDRAFT_129259.1.1,,,,,,,GLUS_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),glutamate biosynthetic process [GO:0006537] comp143227_c0_seq1,804,43.408,0.50262976,89,590,,5.00E-55,Q92734,Protein TFG (TRK-fused gene protein),Protein TFG (TRK-fused gene protein),GO:0008219; GO:0005737; GO:0043123; GO:0004871,cell death; cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity,PF00564;,,,,,,,,,TFG_HUMAN,Homo sapiens (Human),COPII vesicle coating [GO:0048208]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp143228_c0_seq1,2659,43.2869,0.63448077,58,13,,2.00E-10,Q9QY06,Unconventional myosin-IXb (Unconventional myosin-9b),Unconventional myosin-IXb (Unconventional myosin-9b),GO:0005524; GO:0005096; GO:0005100; GO:0007266; GO:0005938; GO:0030010; GO:0032433; GO:0035556; GO:0030027; GO:0072673; GO:0048246; GO:0046872; GO:0000146; GO:0002548; GO:0016459; GO:0048471; GO:0043547; GO:0001726,ATP binding; GTPase activator activity; Rho GTPase activator activity; Rho protein signal transduction; cell cortex; establishment of cell polarity; filopodium tip; intracellular signal transduction; lamellipodium; lamellipodium morphogenesis; macrophage chemotaxis; metal ion binding; microfilament motor activity; monocyte chemotaxis; myosin complex; perinuclear region of cytoplasm; positive regulation of GTPase activity; ruffle,PF00612;PF00063;PF00788;PF00620;,1.00E-26,CHOYP_LOC660076.1.1,,,,,,,MYO9B_MOUSE,Mus musculus (Mouse),actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] comp143228_c0_seq2,2677,43.1827,0.64127594,168,65,,6.00E-42,Q5F3G0,Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19),Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19),GO:0005096; GO:0005622; GO:0043547; GO:0007165,GTPase activator activity; intracellular; positive regulation of GTPase activity; signal transduction,PF00620;,3.00E-28,CHOYP_LOC660076.1.1,,,,,,,RHG19_CHICK,Gallus gallus (Chicken),signal transduction [GO:0007165] comp143229_c0_seq1,1618,42.2126,0.40450606,0,0,,5.00E-97,Q8BH70,F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4),F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00646;,,,,,,,,,FBXL4_MOUSE,Mus musculus (Mouse), comp143229_c0_seq2,1746,35.6243,0.29410784,0,0,,2.00E-15,Q9C5D2,F-box/LRR-repeat protein 4 (AtFBL4),F-box/LRR-repeat protein 4 (AtFBL4),,,PF12937;PF13516;,,,,,,,,,FBL4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp143229_c0_seq3,2547,38.1233,0.36180106,0,0,,9.00E-119,Q8BH70,F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4),F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00646;,,,,,,,,,FBXL4_MOUSE,Mus musculus (Mouse), comp143229_c0_seq4,817,40.8813,0.35258674,0,0,,6.00E-06,Q5U201,Protein AMN1 homolog,Protein AMN1 homolog,,,PF13516;,,,,,,,,,AMN1_RAT,Rattus norvegicus (Rat), comp143229_c0_seq6,1484,33.558,0.2958316,0,0,,6.00E-12,Q6NW95,F-box/LRR-repeat protein 15,F-box/LRR-repeat protein 15,GO:0000086; GO:0019005; GO:0031146; GO:0030282; GO:0005737; GO:0009953; GO:0030513; GO:0016567,G2/M transition of mitotic cell cycle; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; bone mineralization; cytoplasm; dorsal/ventral pattern formation; positive regulation of BMP signaling pathway; protein ubiquitination,PF00646;,,,,,,,,,FXL15_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp143229_c1_seq1,3779,43.186,0.35965478,286,1304,,0,Q8TDG4,Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase),Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase),GO:0005524; GO:0008026; GO:0003676; GO:0005730,ATP binding; ATP-dependent helicase activity; nucleic acid binding; nucleolus,PF00270;PF00271;,4.00E-130,CHOYP_HELQ.1.1,,,,,,,HELQ_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724] comp143231_c1_seq1,1543,39.4038,0.42206567,436,1726,,5.00E-146,P00636,"Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1)","Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase)",GO:0016208; GO:0035690; GO:0071286; GO:0005829; GO:0042132; GO:0006002; GO:0006094; GO:0046872; GO:0048029; GO:0046580; GO:0030308; GO:0045820; GO:0051289; GO:0006111,"AMP binding; cellular response to drug; cellular response to magnesium ion; cytosol; fructose 1,6-bisphosphate 1-phosphatase activity; fructose 6-phosphate metabolic process; gluconeogenesis; metal ion binding; monosaccharide binding; negative regulation of Ras protein signal transduction; negative regulation of cell growth; negative regulation of glycolysis; protein homotetramerization; regulation of gluconeogenesis",PF00316;,5.00E-105,CHOYP_ISCW_ISCW005292.1.1,,,,,,,F16P1_PIG,Sus scrofa (Pig),cellular response to drug [GO:0035690]; cellular response to magnesium ion [GO:0071286]; dephosphorylation [GO:0016311]; fructose 6-phosphate metabolic process [GO:0006002]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of glycolytic process [GO:0045820]; negative regulation of Ras protein signal transduction [GO:0046580]; protein homotetramerization [GO:0051289]; regulation of gluconeogenesis [GO:0006111] comp143232_c0_seq2,2255,37.0288,0.40250017,1012,1981,,2.00E-58,A5GFX0,Protein slowmo homolog 2,PRELI domain containing protein 3B (Protein slowmo homolog 2),GO:0005739,mitochondrion,PF04707;,,,,,,,,,SLMO2_PIG,Sus scrofa (Pig), comp143236_c1_seq1,5281,37.9852,0.41452086,21,86,,0,Q9WUB3,"Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)","Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)",GO:0005980; GO:0008184; GO:0000166; GO:0030170,glycogen catabolic process; glycogen phosphorylase activity; nucleotide binding; pyridoxal phosphate binding,PF00343;,0,CHOYP_LOC100883864.1.1,,,,,,,PYGM_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874]; glycogen catabolic process [GO:0005980]; response to cAMP [GO:0051591]; response to hypoxia [GO:0001666] comp143236_c1_seq3,2297,45.4071,0.48637639,0,6,,0,Q9XTL9,Glycogen phosphorylase (EC 2.4.1.1),Glycogen phosphorylase (EC 2.4.1.1),GO:0050829; GO:0060361; GO:0005980; GO:0008184; GO:0045824; GO:0030170,defense response to Gram-negative bacterium; flight; glycogen catabolic process; glycogen phosphorylase activity; negative regulation of innate immune response; pyridoxal phosphate binding,PF00343;,,,2.00E-70,ruditapes_c10446,,,,,PYG_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; determination of adult lifespan [GO:0008340]; flight [GO:0060361]; glycogen catabolic process [GO:0005980]; negative regulation of innate immune response [GO:0045824]; positive regulation of glycogen catabolic process [GO:0045819] comp143237_c1_seq4,2964,34.5142,0.54690929,178,1770,,,,,,,,,,,1.00E-11,ruditapes_c7836,,,,,,, comp143238_c1_seq1,4050,35.1358,0.44937466,3977,10788,,4.00E-157,Q99K85,Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Endometrial progesterone-induced protein) (EPIP) (Phosphohydroxythreonine aminotransferase),Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Endometrial progesterone-induced protein) (EPIP) (Phosphohydroxythreonine aminotransferase),GO:0006564; GO:0004648; GO:0030170,L-serine biosynthetic process; O-phospho-L-serine:2-oxoglutarate aminotransferase activity; pyridoxal phosphate binding,PF00266;,3.00E-81,CHOYP_BRAFLDRAFT_270672.1.1,3.00E-21,ruditapes_c9501,,,,,SERC_MOUSE,Mus musculus (Mouse),L-serine biosynthetic process [GO:0006564] comp143239_c0_seq1,1566,41.5709,0.5644815,7,98,,1.00E-15,P08655,Uncharacterized 19.7 kDa protein in mercuric resistance operon,Uncharacterized 19.7 kDa protein in mercuric resistance operon,GO:0045454; GO:0050660; GO:0016491,cell redox homeostasis; flavin adenine dinucleotide binding; oxidoreductase activity,PF02852;,,,,,,,,,YMER_STAAU,Staphylococcus aureus,cell redox homeostasis [GO:0045454] comp143239_c0_seq2,2450,41.8367,0.74331475,67,354,,0,P47791,"Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)","Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)",GO:0050661; GO:0045454; GO:0050660; GO:0006749; GO:0004362; GO:0005739,NADP binding; cell redox homeostasis; flavin adenine dinucleotide binding; glutathione metabolic process; glutathione-disulfide reductase activity; mitochondrion,PF07992;PF02852;,2.00E-149,CHOYP_LOC100561262.1.1,,,,,,,GSHR_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749] comp143239_c0_seq3,3348,40.92,0.7861503,100,386,,0,P47791,"Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)","Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)",GO:0050661; GO:0045454; GO:0050660; GO:0006749; GO:0004362; GO:0005739,NADP binding; cell redox homeostasis; flavin adenine dinucleotide binding; glutathione metabolic process; glutathione-disulfide reductase activity; mitochondrion,PF07992;PF02852;,4.00E-40,CHOYP_LOC100375210.2.3,,,,,,,GSHR_MOUSE,Mus musculus (Mouse),cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749] comp143240_c0_seq1,6965,37.8751,0.88940077,478,1,male>female,4.00E-16,Q5CZC0,Fibrous sheath-interacting protein 2,Fibrous sheath-interacting protein 2,,,PF15783;,,,,,,,,,FSIP2_HUMAN,Homo sapiens (Human), comp143240_c0_seq2,6902,37.8731,0.88928558,340,0,male,4.00E-16,Q5CZC0,Fibrous sheath-interacting protein 2,Fibrous sheath-interacting protein 2,,,PF15783;,,,,,,,,,FSIP2_HUMAN,Homo sapiens (Human), comp143241_c0_seq1,2574,40.6371,0.44444818,24,187,,4.00E-55,O75486,Transcription initiation protein SPT3 homolog (SPT3-like protein),Transcription initiation protein SPT3 homolog (SPT3-like protein),GO:0006352; GO:0030914; GO:0043966; GO:0016578; GO:0045893; GO:0006357; GO:0003713; GO:0033276; GO:0006366,"DNA-dependent transcription, initiation; STAGA complex; histone H3 acetylation; histone deubiquitination; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor TFTC complex; transcription from RNA polymerase II promoter",PF02269;,,,,,,,,,SUPT3_HUMAN,Homo sapiens (Human),"histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]; xenophagy [GO:0098792]" comp143241_c0_seq4,1015,47.2906,0.37590551,8,63,,1.00E-54,O75486,Transcription initiation protein SPT3 homolog (SPT3-like protein),Transcription initiation protein SPT3 homolog (SPT3-like protein),GO:0006352; GO:0030914; GO:0043966; GO:0016578; GO:0045893; GO:0006357; GO:0003713; GO:0033276; GO:0006366,"DNA-dependent transcription, initiation; STAGA complex; histone H3 acetylation; histone deubiquitination; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor TFTC complex; transcription from RNA polymerase II promoter",PF02269;,,,,,,,,,SUPT3_HUMAN,Homo sapiens (Human),"histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]; xenophagy [GO:0098792]" comp143242_c0_seq2,1127,37.5333,0.26080945,74,357,,2.00E-39,Q5RA37,Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2),Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2),GO:0008420; GO:0016591; GO:0005737; GO:0070940; GO:0046872; GO:0009301,"CTD phosphatase activity; DNA-directed RNA polymerase II, holoenzyme; cytoplasm; dephosphorylation of RNA polymerase II C-terminal domain; metal ion binding; snRNA transcription",PF04181;,2.00E-14,CHOYP_RPAP2.1.1,,,,,,,RPAP2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; snRNA transcription [GO:0009301] comp143244_c2_seq1,1744,37.328,0.59576667,215,1457,,5.00E-103,Q2KID2,Endonuclease III-like protein 1 (EC 4.2.99.18),Endonuclease III-like protein 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycoslyase/AP lyase),GO:0051539; GO:0019104; GO:0003906; GO:0006285; GO:0003690; GO:0046872; GO:0005739; GO:0006296; GO:0005634,"4 iron, 4 sulfur cluster binding; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; base-excision repair, AP site formation; double-stranded DNA binding; metal ion binding; mitochondrion; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleus",PF00633;PF00730;,6.00E-92,CHOYP_LOC763904.2.2,,,,,,,NTHL1_BOVIN,Bos taurus (Bovine),"base-excision repair, AP site formation [GO:0006285]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]" comp143247_c0_seq2,1176,44.3878,0.49116986,20,0,,5.00E-95,Q5REY7,UBX domain-containing protein 7,UBX domain-containing protein 7,GO:0034098,Cdc48p-Npl4p-Ufd1p AAA ATPase complex,PF00789;,,,,,,,,,UBXN7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp143247_c0_seq3,1106,44.575,0.4625455,0,0,,4.00E-36,O14048,UBX domain-containing protein 2,UBX domain-containing protein 2,GO:0005737; GO:0005634; GO:0043161,cytoplasm; nucleus; proteasomal ubiquitin-dependent protein catabolic process,PF00789;,4.00E-35,CHOYP_UBXN7.1.1,,,,,,,UBX2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511] comp143247_c0_seq4,951,39.0116,0.60866095,164,34,,9.00E-09,Q9UNN5,FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A),FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A),GO:0031265; GO:0034098; GO:0006915; GO:0008219; GO:0007253; GO:0005829; GO:0031072; GO:0005635; GO:0005634; GO:0048471; GO:0043065; GO:0031334; GO:0043161; GO:0019901; GO:0019887; GO:0030155; GO:0042176; GO:0043130; GO:0031625,CD95 death-inducing signaling complex; Cdc48p-Npl4p-Ufd1p AAA ATPase complex; apoptotic process; cell death; cytoplasmic sequestering of NF-kappaB; cytosol; heat shock protein binding; nuclear envelope; nucleus; perinuclear region of cytoplasm; positive regulation of apoptotic process; positive regulation of protein complex assembly; proteasomal ubiquitin-dependent protein catabolic process; protein kinase binding; protein kinase regulator activity; regulation of cell adhesion; regulation of protein catabolic process; ubiquitin binding; ubiquitin protein ligase binding,PF00789;,,,,,,,,,FAF1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176] comp143247_c0_seq5,1152,44.3576,0.46630822,5,0,,3.00E-94,Q5REY7,UBX domain-containing protein 7,UBX domain-containing protein 7,GO:0034098,Cdc48p-Npl4p-Ufd1p AAA ATPase complex,PF00789;,4.00E-35,CHOYP_UBXN7.1.1,,,,,,,UBXN7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp143248_c0_seq1,14180,41.9958,0.26762463,20048,338,,0,Q91XQ0,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0031514,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; motile cilium,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYH8.2.2,,,,,,,DYH8_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp143248_c0_seq2,2142,40.1961,0.3244337,42,0,,0,Q91XQ0,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0031514,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; motile cilium,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYH8.2.2,,,,,,,DYH8_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp143249_c0_seq1,1824,44.6272,0.47707212,215,313,,0,Q9WU78,Programmed cell death 6-interacting protein (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (E2F1-inducible protein) (Eig2),Programmed cell death 6-interacting protein (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (E2F1-inducible protein) (Eig2),GO:0006915; GO:0007049; GO:0051301; GO:0005829; GO:0042470; GO:0005815; GO:0015031,apoptotic process; cell cycle; cell division; cytosol; melanosome; microtubule organizing center; protein transport,PF13949;PF03097;,5.00E-175,CHOYP_BRAFLDRAFT_129885.1.2,,,,,,,PDC6I_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell separation after cytokinesis [GO:0000920]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of extracellular exosome assembly [GO:1903551]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; viral budding via host ESCRT complex [GO:0039702] comp143250_c0_seq1,2034,38.7414,0.38716903,130,195,,2.00E-138,Q0P5H7,"Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)","Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)",GO:0005524; GO:0004814; GO:0006420; GO:0005759,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation; mitochondrial matrix,PF05746;PF00750;,,,,,,,,,SYRM_BOVIN,Bos taurus (Bovine),arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543] comp143250_c0_seq3,511,35.8121,0.50568095,3,0,,8.00E-27,Q0P5H7,"Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)","Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)",GO:0005524; GO:0004814; GO:0006420; GO:0005759,ATP binding; arginine-tRNA ligase activity; arginyl-tRNA aminoacylation; mitochondrial matrix,PF05746;PF00750;,,,,,,,,,SYRM_BOVIN,Bos taurus (Bovine),arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543] comp143251_c2_seq3,1263,37.6089,0.72058422,7,42,,4.00E-34,Q7ZV80,Survival of motor neuron-related-splicing factor 30 (Survival motor neuron domain-containing protein 1),Survival of motor neuron-related-splicing factor 30 (Survival motor neuron domain-containing protein 1),GO:0015030; GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0016607; GO:0005681,Cajal body; RNA binding; RNA splicing; cytoplasm; mRNA processing; nuclear speck; spliceosomal complex,PF06003;,1.00E-35,CHOYP_ISCW_ISCW001190.1.1,5.00E-44,ruditapes_c22217,,,,,SPF30_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp143252_c0_seq1,3086,42.9682,0.55864478,4,69,,0,B2GU58,Kinesin-like protein KIF11 (Costal2),Kinesin-like protein KIF11 (Costal2),GO:0005524; GO:0051301; GO:0005813; GO:0005737; GO:0005871; GO:0008017; GO:0003777; GO:0007018; GO:0007067; GO:0019901; GO:0005876; GO:0000922,ATP binding; cell division; centrosome; cytoplasm; kinesin complex; microtubule binding; microtubule motor activity; microtubule-based movement; mitosis; protein kinase binding; spindle microtubule; spindle pole,PF00225;PF13931;,1.00E-179,CHOYP_KI11A.1.1,,,,,,,KIF11_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based movement [GO:0007018]; mitotic spindle assembly [GO:0090307] comp143252_c0_seq2,3449,42.5341,0.53747804,204,256,,0,B2GU58,Kinesin-like protein KIF11 (Costal2),Kinesin-like protein KIF11 (Costal2),GO:0005524; GO:0051301; GO:0005813; GO:0005737; GO:0005871; GO:0008017; GO:0003777; GO:0007018; GO:0007067; GO:0019901; GO:0005876; GO:0000922,ATP binding; cell division; centrosome; cytoplasm; kinesin complex; microtubule binding; microtubule motor activity; microtubule-based movement; mitosis; protein kinase binding; spindle microtubule; spindle pole,PF00225;PF13931;,1.00E-180,CHOYP_KI11A.1.1,,,,,,,KIF11_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based movement [GO:0007018]; mitotic spindle assembly [GO:0090307] comp143253_c1_seq4,1244,45.9003,0.32127869,0,0,,7.00E-07,Q9FF61,Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 (SMARCA3-like protein 1) (EC 3.6.4.-),Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 (SMARCA3-like protein 1) (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0016568; GO:0004386; GO:0005634; GO:0006351; GO:0008270,"ATP binding; DNA binding; chromatin modification; helicase activity; nucleus; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,,,,,,,,,SM3L1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]" comp143253_c1_seq5,1934,44.726,0.38369411,0,0,,2.00E-70,Q08E13,RING finger protein 10,RING finger protein 10,GO:0005737; GO:0045893; GO:0008270,"cytoplasm; positive regulation of transcription, DNA-dependent; zinc ion binding",PF13639;,,,,,,,,,RNF10_BOVIN,Bos taurus (Bovine),"positive regulation of transcription, DNA-templated [GO:0045893]; protein autoubiquitination [GO:0051865]" comp143253_c1_seq6,1934,44.8811,0.38075976,0,0,,1.00E-70,Q08E13,RING finger protein 10,RING finger protein 10,GO:0005737; GO:0045893; GO:0008270,"cytoplasm; positive regulation of transcription, DNA-dependent; zinc ion binding",PF13639;,1.00E-43,CHOYP_RNF10.1.1,,,,,,,RNF10_BOVIN,Bos taurus (Bovine),"positive regulation of transcription, DNA-templated [GO:0045893]; protein autoubiquitination [GO:0051865]" comp143253_c1_seq7,1244,45.6592,0.32506144,0,0,,7.00E-07,Q9FF61,Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 (SMARCA3-like protein 1) (EC 3.6.4.-),Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 (SMARCA3-like protein 1) (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0016568; GO:0004386; GO:0005634; GO:0006351; GO:0008270,"ATP binding; DNA binding; chromatin modification; helicase activity; nucleus; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,2.00E-38,CHOYP_RNF10.1.1,,,,,,,SM3L1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]" comp143254_c0_seq1,3417,41.3521,0.41002216,122,146,,1.00E-24,P25823,Maternal protein tudor,Maternal protein tudor,GO:0043186; GO:0030719; GO:0008298; GO:0019090; GO:0005739; GO:0005634; GO:0007277,P granule; P granule organization; intracellular mRNA localization; mitochondrial rRNA export from mitochondrion; mitochondrion; nucleus; pole cell development,PF00567;,,,,,,,,,TUD_DROME,Drosophila melanogaster (Fruit fly),germ cell development [GO:0007281]; intracellular mRNA localization [GO:0008298]; mitochondrial rRNA export from mitochondrion [GO:0019090]; P granule organization [GO:0030719]; pole cell development [GO:0007277]; pole cell fate determination [GO:0007278]; pole plasm assembly [GO:0007315] comp143254_c0_seq2,3363,40.4996,0.41800666,8,38,,5.00E-22,Q9BXT4,Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1),Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1),GO:0043046; GO:0033391; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; chromatoid body; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_HUMAN,Homo sapiens (Human),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp143255_c1_seq2,685,38.2482,0.44637776,123,397,,1.00E-22,E1BSW7,Centromere protein S (CENP-S),Centromere protein S (CENP-S),GO:0003677; GO:0006281; GO:0051301; GO:0000777; GO:0007067; GO:0005634,DNA binding; DNA repair; cell division; condensed chromosome kinetochore; mitosis; nucleus,PF15630;,,,,,,,,,CENPS_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; interstrand cross-link repair [GO:0036297]; mitotic nuclear division [GO:0007067]; mitotic recombination [GO:0006312]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp143256_c0_seq1,3287,36.0815,0.59515763,2531,11015,,0,O43242,26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58),26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58),GO:0006977; GO:0000082; GO:0031145; GO:0002479; GO:0006915; GO:0005829; GO:0030234; GO:0010467; GO:0016071; GO:0043066; GO:0051436; GO:0005654; GO:0051437; GO:0022624; GO:0000209; GO:0006521; GO:0042176; GO:0044281; GO:0016032,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; G1/S transition of mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; apoptotic process; cytosol; enzyme regulator activity; gene expression; mRNA metabolic process; negative regulation of apoptotic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; proteasome accessory complex; protein polyubiquitination; regulation of cellular amino acid metabolic process; regulation of protein catabolic process; small molecule metabolic process; viral process",PF01399;PF08375;,4.00E-154,CHOYP_LOC100375022.1.1,,,,,,,PSMD3_HUMAN,Homo sapiens (Human),"anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp143257_c0_seq1,1798,38.3204,0.33706364,68,40,,2.00E-129,Q9QUM7,MutS protein homolog 5,MutS protein homolog 5,GO:0005524; GO:0008094; GO:0051026; GO:0007292; GO:0045143; GO:0006298; GO:0030983; GO:0005654; GO:0007131; GO:0000795,ATP binding; DNA-dependent ATPase activity; chiasma assembly; female gamete generation; homologous chromosome segregation; mismatch repair; mismatched DNA binding; nucleoplasm; reciprocal meiotic recombination; synaptonemal complex,PF05192;PF05190;PF00488;,2.00E-92,CHOYP_NEMVEDRAFT_V1G238590.1.1,,,,,,,MSH5_MOUSE,Mus musculus (Mouse),chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; meiosis I [GO:0007127]; mismatch repair [GO:0006298]; synapsis [GO:0007129] comp143257_c0_seq5,1812,38.4658,0.33165931,62,6,,3.00E-129,Q9QUM7,MutS protein homolog 5,MutS protein homolog 5,GO:0005524; GO:0008094; GO:0051026; GO:0007292; GO:0045143; GO:0006298; GO:0030983; GO:0005654; GO:0007131; GO:0000795,ATP binding; DNA-dependent ATPase activity; chiasma assembly; female gamete generation; homologous chromosome segregation; mismatch repair; mismatched DNA binding; nucleoplasm; reciprocal meiotic recombination; synaptonemal complex,PF05192;PF05190;PF00488;,,,,,,,,,MSH5_MOUSE,Mus musculus (Mouse),chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; meiosis I [GO:0007127]; mismatch repair [GO:0006298]; synapsis [GO:0007129] comp143258_c3_seq1,3137,35.161,0.55023495,1163,10044,,7.00E-115,P83686,NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) (Fragment),NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) (Fragment),GO:0006695; GO:0004128; GO:0017144; GO:0005789; GO:0030497; GO:0050660; GO:0005741; GO:0006636,"cholesterol biosynthetic process; cytochrome-b5 reductase activity, acting on NAD(P)H; drug metabolic process; endoplasmic reticulum membrane; fatty acid elongation; flavin adenine dinucleotide binding; mitochondrial outer membrane; unsaturated fatty acid biosynthetic process",PF00970;PF00175;,1.00E-102,CHOYP_BRAFLDRAFT_120433.1.1,,,,,,,NB5R3_PIG,Sus scrofa (Pig),cholesterol biosynthetic process [GO:0006695] comp143260_c0_seq1,2005,36.1097,1.0411317,669,8839,,2.00E-07,Q9ESN4,Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin),Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin),GO:0005581; GO:0005576; GO:0050807,collagen; extracellular region; regulation of synapse organization,PF00386;PF01391;,,,,,,,,,C1QL3_MOUSE,Mus musculus (Mouse),regulation of synapse organization [GO:0050807] comp143261_c2_seq1,2129,39.643,1.12553991,7,214,,6.00E-27,Q4WHA3,Actin-related protein 4 (Actin-like protein arp4) (Actin-like protein 4),Actin-related protein 4 (Actin-like protein arp4) (Actin-like protein 4),GO:0006281; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"DNA repair; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00022;,,,8.00E-13,ruditapes_c18995,,,,,ARP4_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),"chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143261_c2_seq2,2599,37.3605,1.05901836,0,69,,4.00E-92,P02578,Actin-1,Actin-1,GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,,,,,,,,,ACT1_ACACA,Acanthamoeba castellanii (Amoeba), comp143261_c2_seq4,2409,39.0619,1.03522355,19,167,,2.00E-85,P07828,Actin-18 (Actin-3-sub 2),Actin-18 (Actin-3-sub 2),GO:0005524; GO:0015629; GO:0000902; GO:0005737; GO:0017022; GO:0005200,ATP binding; actin cytoskeleton; cell morphogenesis; cytoplasm; myosin binding; structural constituent of cytoskeleton,PF00022;,6.00E-11,CHOYP_ACT1.4.7,,,,,,,ACT18_DICDI,Dictyostelium discoideum (Slime mold), comp143263_c0_seq1,2016,41.5179,0.41110539,2,0,,4.00E-39,Q80YG3,Kelch domain-containing protein 1,Kelch domain-containing protein 1,GO:0005737,cytoplasm,PF07646;,,,,,,,,,KLDC1_MOUSE,Mus musculus (Mouse), comp143263_c0_seq2,2200,41.5,0.442423,0,0,,4.00E-14,Q7M3S9,RING finger protein B (Protein rngB),RING finger protein B (Protein rngB),GO:0005737; GO:0008270,cytoplasm; zinc ion binding,PF01344;,,,,,,,,,RNGB_DICDI,Dictyostelium discoideum (Slime mold), comp143263_c0_seq3,2492,39.2857,0.3988129,0,0,,2.00E-24,Q9MA55,Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4),Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4),GO:0005737; GO:0005829; GO:0000062; GO:0008289; GO:0006869; GO:0005634; GO:0009723; GO:0009753; GO:0009416; GO:0006810,cytoplasm; cytosol; fatty-acyl-CoA binding; lipid binding; lipid transport; nucleus; response to ethylene stimulus; response to jasmonic acid stimulus; response to light stimulus; transport,PF00887;,,,,,,,,,ACBP4_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to light stimulus [GO:0009416]; transport [GO:0006810] comp143263_c0_seq4,2215,41.4447,0.45138521,0,0,,9.00E-18,Q6AYI2,Kelch domain-containing protein 3,Kelch domain-containing protein 3,GO:0003682; GO:0005737; GO:0007126; GO:0000790,chromatin binding; cytoplasm; meiosis; nuclear chromatin,PF07646;,,,,,,,,,KLDC3_RAT,Rattus norvegicus (Rat),meiotic cell cycle [GO:0051321] comp143263_c0_seq5,2001,41.6292,0.41177449,0,0,,3.00E-25,Q93XW5,Nitrile-specifier protein 5 (AtNSP5),Nitrile-specifier protein 5 (AtNSP5),GO:0005829; GO:0019762; GO:0080028,cytosol; glucosinolate catabolic process; nitrile biosynthetic process,PF01344;,,,,,,,,,NSP5_ARATH,Arabidopsis thaliana (Mouse-ear cress),glucosinolate catabolic process [GO:0019762]; nitrile biosynthetic process [GO:0080028] comp143263_c0_seq6,2507,39.2501,0.40763839,0,0,,2.00E-38,Q80YG3,Kelch domain-containing protein 1,Kelch domain-containing protein 1,GO:0005737,cytoplasm,PF07646;,,,,,,,,,KLDC1_MOUSE,Mus musculus (Mouse), comp143265_c0_seq1,4918,38.7556,0.4800041,2441,2724,,7.00E-34,Q6PB66,"Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (mLRP130)","Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (mLRP130)",GO:0003723; GO:0048487; GO:0000794; GO:0005856; GO:0051028; GO:0005874; GO:0042645; GO:0005739; GO:0000961; GO:0005637; GO:0005640; GO:0005654; GO:0048471; GO:0070129; GO:0006355; GO:0030529; GO:0003697; GO:0006351,"RNA binding; beta-tubulin binding; condensed nuclear chromosome; cytoskeleton; mRNA transport; microtubule; mitochondrial nucleoid; mitochondrion; negative regulation of mitochondrial RNA catabolic process; nuclear inner membrane; nuclear outer membrane; nucleoplasm; perinuclear region of cytoplasm; regulation of mitochondrial translation; regulation of transcription, DNA-dependent; ribonucleoprotein complex; single-stranded DNA binding; transcription, DNA-dependent",PF01535;PF13812;,,,,,,,,,LPPRC_MOUSE,Mus musculus (Mouse),"mRNA transport [GO:0051028]; negative regulation of mitochondrial RNA catabolic process [GO:0000961]; regulation of mitochondrial translation [GO:0070129]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143266_c1_seq3,621,34.9436,0.59672229,6,88,,5.00E-21,Q9HD34,LYR motif-containing protein 4,LYR motif-containing protein 4,GO:0005759; GO:0005634; GO:0044281,mitochondrial matrix; nucleus; small molecule metabolic process,PF05347;,,,,,,,,,LYRM4_HUMAN,Homo sapiens (Human),small molecule metabolic process [GO:0044281] comp143268_c1_seq1,2623,43.8811,0.54484372,570,2963,,0,Q08C92,tRNA wybutosine-synthesizing protein 1 homolog (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA-yW-synthesizing protein),S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein),GO:0051539; GO:0010181; GO:0005506; GO:0016491; GO:0008033,"4 iron, 4 sulfur cluster binding; FMN binding; iron ion binding; oxidoreductase activity; tRNA processing",PF00258;PF04055;PF08608;,6.00E-157,CHOYP_TYW1.1.1,,,,,,,TYW1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),oxidation-reduction process [GO:0055114]; tRNA processing [GO:0008033] comp143272_c0_seq1,2655,38.1921,0.4914182,408,2708,,2.00E-104,Q8NC60,Nitric oxide-associated protein 1,Nitric oxide-associated protein 1,GO:0005525; GO:0003924; GO:0006915; GO:0005743; GO:0032543; GO:0010941; GO:0043457; GO:0042254,GTP binding; GTPase activity; apoptotic process; mitochondrial inner membrane; mitochondrial translation; regulation of cell death; regulation of cellular respiration; ribosome biogenesis,PF01926;,,,,,,,,,NOA1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; mitochondrial translation [GO:0032543]; regulation of cell death [GO:0010941]; regulation of cellular respiration [GO:0043457]; ribosome biogenesis [GO:0042254] comp143274_c1_seq1,3039,45.0477,0.30497465,0,0,,8.00E-116,A0JN53,RNA polymerase II-associated protein 1,RNA polymerase II-associated protein 1,GO:0003677; GO:0003899; GO:0032774; GO:0005634,DNA binding; DNA-directed RNA polymerase activity; RNA biosynthetic process; nucleus,PF08620;PF08621;,2.00E-24,CHOYP_RPAP1.2.4,,,,,,,RPAP1_BOVIN,Bos taurus (Bovine),transcription from RNA polymerase II promoter [GO:0006366] comp143274_c1_seq2,3868,44.4157,0.3041502,7,26,,4.00E-14,O43088,RNA polymerase II-associated protein rba50,RNA polymerase II-associated protein rba50,GO:0005665; GO:0005829; GO:0006366,"DNA-directed RNA polymerase II, core complex; cytosol; transcription from RNA polymerase II promoter",PF08620;PF08621;,4.00E-22,CHOYP_RPAP1.1.4,,,,,,,RBA50_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),transcription from RNA polymerase II promoter [GO:0006366] comp143274_c1_seq3,4026,44.4113,0.32761147,27,96,,9.00E-97,Q3T1I9,RNA polymerase II-associated protein 1,RNA polymerase II-associated protein 1,GO:0003677; GO:0003899; GO:0032774; GO:0005634,DNA binding; DNA-directed RNA polymerase activity; RNA biosynthetic process; nucleus,PF08620;PF08621;,,,,,,,,,RPAP1_RAT,Rattus norvegicus (Rat),transcription from RNA polymerase II promoter [GO:0006366] comp143274_c1_seq4,1907,44.4678,0.31848312,8,0,,2.00E-63,A0JN53,RNA polymerase II-associated protein 1,RNA polymerase II-associated protein 1,GO:0003677; GO:0003899; GO:0032774; GO:0005634,DNA binding; DNA-directed RNA polymerase activity; RNA biosynthetic process; nucleus,PF08620;PF08621;,1.00E-24,CHOYP_RPAP1.2.4,,,,,,,RPAP1_BOVIN,Bos taurus (Bovine),transcription from RNA polymerase II promoter [GO:0006366] comp143276_c0_seq3,3132,43.7739,0.35561104,0,0,,8.00E-180,Q3UHH1,Zinc finger SWIM domain-containing protein 8,Zinc finger SWIM domain-containing protein 8,GO:0008270,zinc ion binding,,0,CHOYP_ZSWM8.1.1,,,,,,,K0913_MOUSE,Mus musculus (Mouse), comp143276_c0_seq7,2449,44.8755,0.30941134,0,0,,,,,,,,,,,3.00E-50,ruditapes_c28471,,,,,,, comp143276_c0_seq8,3459,43.741,0.33996564,0,0,,1.00E-178,Q3UHH1,Zinc finger SWIM domain-containing protein 8,Zinc finger SWIM domain-containing protein 8,GO:0008270,zinc ion binding,,,,,,,,,,K0913_MOUSE,Mus musculus (Mouse), comp143276_c0_seq9,2776,44.7046,0.2962573,0,0,,,,,,,,,4.00E-178,CHOYP_ZSWM8.1.1,,,,,,,,, comp143277_c0_seq1,1737,34.8877,0.29223846,32,322,,6.00E-06,Q9D416,ADP-ribosylation factor-like protein 13A,ADP-ribosylation factor-like protein 13A,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00025;,,,,,,,,,AR13A_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp143277_c0_seq2,1723,35.1132,0.29070562,10,125,,3.00E-89,P61212,ADP-ribosylation factor-like protein 1,ADP-ribosylation factor-like protein 1,GO:0005525; GO:0003924; GO:0005794; GO:0000139; GO:0007030; GO:0048193; GO:0031584; GO:0008047; GO:0046872; GO:0034067; GO:0042147; GO:0007264; GO:0009404; GO:0005802,"GTP binding; GTPase activity; Golgi apparatus; Golgi membrane; Golgi organization; Golgi vesicle transport; activation of phospholipase D activity; enzyme activator activity; metal ion binding; protein localization to Golgi apparatus; retrograde transport, endosome to Golgi; small GTPase mediated signal transduction; toxin metabolic process; trans-Golgi network",PF00025;,8.00E-103,CHOYP_BRAFLDRAFT_86801.1.1,5.00E-14,ruditapes2_c1053,,,,,ARL1_RAT,Rattus norvegicus (Rat),"activation of phospholipase D activity [GO:0031584]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; small GTPase mediated signal transduction [GO:0007264]; toxin metabolic process [GO:0009404]" comp143279_c0_seq1,3060,32.3203,0.46449551,0,3,,7.00E-22,A7SFP1,Leucine-rich repeat protein soc-2 homolog,Leucine-rich repeat protein soc-2 homolog,GO:0046579; GO:0000164,positive regulation of Ras protein signal transduction; protein phosphatase type 1 complex,PF13855;,8.00E-93,CHOYP_RSU1.1.1,,,,,,,SHOC2_NEMVE,Nematostella vectensis (Starlet sea anemone), comp143279_c0_seq2,3048,32.3819,0.4519046,0,60,,7.00E-123,Q5E9C0,Ras suppressor protein 1 (Rsu-1),Ras suppressor protein 1 (Rsu-1),,,PF13855;,,,,,,,,,RSU1_BOVIN,Bos taurus (Bovine),positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547] comp143279_c0_seq3,3072,32.3568,0.47425734,0,0,,7.00E-22,A7SFP1,Leucine-rich repeat protein soc-2 homolog,Leucine-rich repeat protein soc-2 homolog,GO:0046579; GO:0000164,positive regulation of Ras protein signal transduction; protein phosphatase type 1 complex,PF13855;,,,1.00E-100,ruditapes_c11866,,,,,SHOC2_NEMVE,Nematostella vectensis (Starlet sea anemone), comp143279_c0_seq4,3085,32.2853,0.47434679,3,0,,8.00E-123,Q5E9C0,Ras suppressor protein 1 (Rsu-1),Ras suppressor protein 1 (Rsu-1),,,PF13855;,,,,,,,,,RSU1_BOVIN,Bos taurus (Bovine),positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547] comp143280_c0_seq1,1926,41.2773,0.28406171,12,42,,1.00E-06,Q66HC1,Tudor domain-containing protein 3,Tudor domain-containing protein 3,GO:0003723; GO:0003682; GO:0016568; GO:0005737; GO:0006397; GO:0035064; GO:0005634; GO:0003713,RNA binding; chromatin binding; chromatin modification; cytoplasm; mRNA processing; methylated histone residue binding; nucleus; transcription coactivator activity,PF08585;PF06003;PF00627;,,,,,,,,,TDRD3_RAT,Rattus norvegicus (Rat),chromatin modification [GO:0016568]; mRNA processing [GO:0006397] comp143280_c0_seq3,2546,40.7306,0.28652322,43,287,,1.00E-54,Q6DDH2,RecQ-mediated genome instability protein 1,RecQ-mediated genome instability protein 1,GO:0006260; GO:0005634,DNA replication; nucleus,PF16099;PF08585;,4.00E-14,CHOYP_RMI1.1.1,,,,,,,RMI1_XENLA,Xenopus laevis (African clawed frog),DNA replication [GO:0006260] comp143282_c0_seq2,2863,46.5945,0.56011016,5,0,,2.00E-31,Q8BGD9,Eukaryotic translation initiation factor 4B (eIF-4B),Eukaryotic translation initiation factor 4B (eIF-4B),GO:0000166; GO:0003743,nucleotide binding; translation initiation factor activity,PF00076;,,,,,,,,,IF4B_MOUSE,Mus musculus (Mouse),cytoplasmic translation [GO:0002181]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731] comp143282_c0_seq3,2872,46.4485,0.5541776,0,9,,4.00E-14,Q15056,Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein),Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein),GO:0005829; GO:0048589; GO:0016281; GO:0019048; GO:0000166; GO:0048471; GO:0006446; GO:0019953; GO:0003743,cytosol; developmental growth; eukaryotic translation initiation factor 4F complex; modulation by virus of host morphology or physiology; nucleotide binding; perinuclear region of cytoplasm; regulation of translational initiation; sexual reproduction; translation initiation factor activity,PF00076;,,,,,,,,,IF4H_HUMAN,Homo sapiens (Human),cytoplasmic translation [GO:0002181]; developmental growth [GO:0048589]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; sexual reproduction [GO:0019953]; translational initiation [GO:0006413]; viral process [GO:0016032] comp143282_c0_seq4,2873,46.4671,0.55496653,22,33,,2.00E-31,Q8BGD9,Eukaryotic translation initiation factor 4B (eIF-4B),Eukaryotic translation initiation factor 4B (eIF-4B),GO:0000166; GO:0003743,nucleotide binding; translation initiation factor activity,PF00076;,,,,,,,,,IF4B_MOUSE,Mus musculus (Mouse),cytoplasmic translation [GO:0002181]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731] comp143282_c0_seq5,2888,46.4335,0.55132555,0,0,,4.00E-14,Q15056,Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein),Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein),GO:0005829; GO:0048589; GO:0016281; GO:0019048; GO:0000166; GO:0048471; GO:0006446; GO:0019953; GO:0003743,cytosol; developmental growth; eukaryotic translation initiation factor 4F complex; modulation by virus of host morphology or physiology; nucleotide binding; perinuclear region of cytoplasm; regulation of translational initiation; sexual reproduction; translation initiation factor activity,PF00076;,,,,,,,,,IF4H_HUMAN,Homo sapiens (Human),cytoplasmic translation [GO:0002181]; developmental growth [GO:0048589]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; sexual reproduction [GO:0019953]; translational initiation [GO:0006413]; viral process [GO:0016032] comp143283_c1_seq3,1697,35.2387,0.52313539,232,654,,4.00E-45,Q9VB74,UPF0396 protein CG6066,UPF0396 protein CG6066,GO:0071013; GO:0000398; GO:0022008,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; neurogenesis",PF06047;,5.00E-55,CHOYP_U396.1.1,,,,,,,U396_DROME,Drosophila melanogaster (Fruit fly),"mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; sensory perception of pain [GO:0019233]" comp143284_c0_seq1,1375,34.7636,0.58221853,105,5,,,,,,,,,,,4.00E-14,ruditapes2_c3682,,,,,,, comp143284_c0_seq2,1394,34.792,0.57266039,168,159,,1.00E-23,P82926,"28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt)","28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF08293;,,,4.00E-14,ruditapes_lrc34842,,,,,RT33_BOVIN,Bos taurus (Bovine),mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124] comp143287_c0_seq1,3781,38.429,0.41593383,67,552,,2.00E-10,Q55BR6,Origin recognition complex subunit 3 (Origin replication complex subunit C),Origin recognition complex subunit 3 (Origin replication complex subunit C),GO:0003677; GO:0006260; GO:0005664,DNA binding; DNA replication; nuclear origin of replication recognition complex,PF07034;,2.00E-44,CHOYP_LOC592407.1.1,,,,,,,ORC3_DICDI,Dictyostelium discoideum (Slime mold),DNA replication initiation [GO:0006270]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267] comp143287_c0_seq2,3760,38.484,0.42419188,111,485,,0,Q32PJ3,Origin recognition complex subunit 3,Origin recognition complex subunit 3,GO:0003677; GO:0006260; GO:0005664,DNA binding; DNA replication; nuclear origin of replication recognition complex,PF07034;,3.00E-43,CHOYP_LOC592407.1.1,,,,,,,ORC3_BOVIN,Bos taurus (Bovine),DNA replication initiation [GO:0006270]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267] comp143289_c3_seq1,3769,46.9886,0.3469015,0,0,,2.00E-61,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,2.00E-16,ruditapes_c14298,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp143289_c3_seq4,4301,47.7563,0.3715756,0,0,,3.00E-61,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp143291_c0_seq1,1195,44.5188,0.44440665,133,76,,7.00E-50,Q4R6I5,Clathrin heavy chain linker domain-containing protein 1,Clathrin heavy chain linker domain-containing protein 1,,,PF15739;,2.00E-71,CHOYP_LOC578979.1.1,,,,,,,CLHC1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143291_c0_seq3,478,40.795,0.50421273,0,0,,9.00E-25,Q4R6I5,Clathrin heavy chain linker domain-containing protein 1,Clathrin heavy chain linker domain-containing protein 1,,,PF15739;,,,,,,,,,CLHC1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143293_c0_seq1,1537,37.4105,0.43707237,24,70,,,,,,,,,5.00E-86,CHOYP_LOC100378652.1.1,,,,,,,,, comp143293_c0_seq2,1568,37.1173,0.4365928,64,41,,5.00E-82,Q8BKE9,Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2),Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2),GO:0005813; GO:0003682; GO:0016023; GO:0005634; GO:0033630; GO:0045944,centrosome; chromatin binding; cytoplasmic membrane-bounded vesicle; nucleus; positive regulation of cell adhesion mediated by integrin; positive regulation of transcription from RNA polymerase II promoter,,1.00E-87,CHOYP_LOC100378652.1.1,,,,,,,IFT74_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; keratinocyte development [GO:0003334]; negative regulation of epithelial cell proliferation [GO:0050680]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp143294_c0_seq1,3010,32.2259,0.37144222,3368,11882,,6.00E-49,Q93104,Enhancer of rudimentary homolog,Enhancer of rudimentary homolog,GO:0007049,cell cycle,PF01133;,1.00E-51,CHOYP_E_R_.1.1,7.00E-66,ruditapes2_c7336,,,,,ERH_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),cell cycle [GO:0007049]; positive regulation of Notch signaling pathway [GO:0045747]; pyrimidine nucleotide biosynthetic process [GO:0006221] comp143295_c1_seq1,3944,39.1734,0.38625756,502,474,,5.00E-28,Q68CJ6,Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),GO:0005525; GO:0006184; GO:0003924; GO:0005634,GTP binding; GTP catabolic process; GTPase activity; nucleus,PF00350;,1.00E-59,CHOYP_BRAFLDRAFT_129807.1.1,,,,,,,SLIP_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp143296_c1_seq1,1827,37.0005,0.95313537,3,2745,female>male,8.00E-25,O75369,Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP),Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP),GO:0030018; GO:0003779; GO:0015629; GO:0030036; GO:0005938; GO:0030154; GO:0019221; GO:0007016; GO:0005829; GO:0005925; GO:0016021; GO:0005886; GO:0007519; GO:0001725,Z disc; actin binding; actin cytoskeleton; actin cytoskeleton organization; cell cortex; cell differentiation; cytokine-mediated signaling pathway; cytoskeletal anchoring at plasma membrane; cytosol; focal adhesion; integral to membrane; plasma membrane; skeletal muscle tissue development; stress fiber,PF00307;PF00630;,,,3.00E-11,ruditapes_c7619,,,,,FLNB_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519] comp143298_c1_seq2,1609,41.7029,0.57250573,68,296,,0,Q3TIX9,U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39),U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39),GO:0008380; GO:0007049; GO:0051301; GO:0006397; GO:0005681; GO:0004221; GO:0006511; GO:0008270,RNA splicing; cell cycle; cell division; mRNA processing; spliceosomal complex; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF00443;PF02148;,0,CHOYP_SNUT2.1.1,3.00E-48,ruditapes_c1336,,,,,SNUT2_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA processing [GO:0006397]; protein deubiquitination [GO:0016579]; RNA splicing [GO:0008380] comp143298_c1_seq3,1290,33.9535,0.52406826,8,61,,,,,,,,,,,6.00E-25,ruditapes_c5478,,,,,,, comp143300_c1_seq1,2619,37.3807,0.33246204,1941,7603,,0,Q9JMA1,Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14),Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14),GO:0009986; GO:0008234; GO:0016023; GO:0004866; GO:0005886; GO:0000502; GO:0050920; GO:0061136; GO:0045202; GO:0007268; GO:0004221; GO:0006511,cell surface; cysteine-type peptidase activity; cytoplasmic membrane-bounded vesicle; endopeptidase inhibitor activity; plasma membrane; proteasome complex; regulation of chemotaxis; regulation of proteasomal protein catabolic process; synapse; synaptic transmission; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,0,CHOYP_LOC100373353.1.1,2.00E-53,ruditapes_c8613,,,,,UBP14_MOUSE,Mus musculus (Mouse),chemical synaptic transmission [GO:0007268]; negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; protein deubiquitination [GO:0016579]; regulation of chemotaxis [GO:0050920]; regulation of proteasomal protein catabolic process [GO:0061136]; ubiquitin-dependent protein catabolic process [GO:0006511] comp143302_c0_seq4,1607,47.9776,0.40077076,252,211,,5.00E-86,P35658,Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN),Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN),GO:0005975; GO:0019221; GO:0005829; GO:0010467; GO:0015758; GO:0006406; GO:0016071; GO:0007077; GO:0005643; GO:0005487; GO:0005654; GO:0006611; GO:0006606; GO:0051726; GO:0010827; GO:0044281; GO:0055085; GO:0005215; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; cytosol; gene expression; glucose transport; mRNA export from nucleus; mRNA metabolic process; mitotic nuclear envelope disassembly; nuclear pore; nucleocytoplasmic transporter activity; nucleoplasm; protein export from nucleus; protein import into nucleus; regulation of cell cycle; regulation of glucose transport; small molecule metabolic process; transmembrane transport; transporter activity; viral process,,8.00E-14,CHOYP_NUP214.1.3,5.00E-14,ruditapes_c12377,,,,,NU214_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mRNA stability [GO:0043488]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp143303_c0_seq14,873,41.4662,0.38478038,18,37,,,,,,,,,3.00E-16,CHOYP_LOC100007585.5.7,,,,,,,,, comp143303_c0_seq5,808,36.3861,0.26237068,0,0,,,,,,,,,,,2.00E-21,ruditapes_c24531,,,,,,, comp143303_c0_seq6,494,35.6275,0.44889418,0,0,,,,,,,,,,,9.00E-11,ruditapes_c23328,,,,,,, comp143305_c0_seq1,1729,32.5622,0.61762101,37,158,,5.00E-72,Q9UMY4,Sorting nexin-12,Sorting nexin-12,GO:0007154; GO:0016020; GO:0035091; GO:0015031,cell communication; membrane; phosphatidylinositol binding; protein transport,PF00787;,1.00E-74,CHOYP_LOC100642494.1.1,3.00E-119,ruditapes_c12445,,,,,SNX12_HUMAN,Homo sapiens (Human),negative regulation of early endosome to late endosome transport [GO:2000642]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein processing [GO:0010955]; negative regulation of protein transport [GO:0051224]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; vesicle organization [GO:0016050] comp143305_c0_seq3,1710,32.5731,0.62289391,0,14,,,,,,,,,2.00E-59,CHOYP_LOC100642494.1.1,,,,,,,,, comp143306_c0_seq1,2490,37.7912,0.50996323,256,1909,,1.00E-24,Q3B7N9,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143308_c0_seq1,2530,44.1502,0.69114804,113,278,,3.00E-143,O08658,Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88),Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88),GO:0051028; GO:0005643; GO:0015031,mRNA transport; nuclear pore; protein transport,PF10168;,,,,,,,,,NUP88_RAT,Rattus norvegicus (Rat),mitotic nuclear division [GO:0007067]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] comp143308_c0_seq2,1455,42.6117,0.69729656,34,63,,2.00E-69,Q99567,Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88),Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88),GO:0005975; GO:0019221; GO:0005829; GO:0015758; GO:0051028; GO:0007077; GO:0005643; GO:0015031; GO:0010827; GO:0044281; GO:0055085; GO:0005215; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; cytosol; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear pore; protein transport; regulation of glucose transport; small molecule metabolic process; transmembrane transport; transporter activity; viral process,PF10168;,3.00E-25,CHOYP_BRAFLDRAFT_122018.1.1,,,,,,,NUP88_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp143311_c0_seq1,739,36.9418,0.28508583,449,3031,,3.00E-38,Q9JIX0,Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog),Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog),GO:0000124; GO:0016578; GO:0030374; GO:0051028; GO:0005643; GO:0045893; GO:0015031; GO:0006351,"SAGA complex; histone deubiquitination; ligand-dependent nuclear receptor transcription coactivator activity; mRNA transport; nuclear pore; positive regulation of transcription, DNA-dependent; protein transport; transcription, DNA-dependent",,4.00E-64,CHOYP_LOC100374772.4.4,5.00E-67,ruditapes_c30405,,,,,ENY2_MOUSE,Mus musculus (Mouse),"histone deubiquitination [GO:0016578]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription, DNA-templated [GO:0045893]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp143312_c0_seq1,392,46.9388,0.4186817,0,17,,2.00E-12,Q6ZN79,Zinc finger protein 705A,Zinc finger protein 705A,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,Z705A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143312_c0_seq2,253,46.2451,0.60657664,0,0,,2.00E-11,Q8BIQ8,Zinc finger protein 770,Zinc finger protein 770,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF13912;,,,,,,,,,ZN770_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp143312_c1_seq1,1667,43.5513,0.60816745,5,33,,1.00E-11,Q4V8R6,Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),GO:0003677; GO:0051301; GO:0005737; GO:0016874; GO:0046872; GO:0007067; GO:0005654; GO:0016567; GO:0040008; GO:0006355; GO:0006351,"DNA binding; cell division; cytoplasm; ligase activity; metal ion binding; mitosis; nucleoplasm; protein ubiquitination; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,E4F1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp143312_c1_seq3,1529,42.7731,0.60116217,1,29,,3.00E-08,Q7TQG0,Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ),Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBTB5_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143312_c1_seq4,1669,40.5632,0.48114213,15,114,,5.00E-12,Q6NSZ9,Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498),Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;,,,3.00E-11,ruditapes_c17969,,,,,ZN498_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp143312_c3_seq1,2005,36.1097,1.0411317,211,2298,,2.00E-11,Q9NY84,Vascular non-inflammatory molecule 3 (Vanin-3) (EC 3.5.1.92),Vascular non-inflammatory molecule 3 (Vanin-3) (EC 3.5.1.92),GO:0031225; GO:0005615; GO:0017159; GO:0015939; GO:0005886,anchored to membrane; extracellular space; pantetheine hydrolase activity; pantothenate metabolic process; plasma membrane,PF00795;,,,,,,,,,VNN3_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; central nervous system development [GO:0007417]; pantothenate metabolic process [GO:0015939] comp143312_c4_seq5,1144,43.5315,1.14498241,4,12,,3.00E-65,Q9QZ25,Vascular non-inflammatory molecule 3 (Vanin-3) (EC 3.5.1.92),Vascular non-inflammatory molecule 3 (Vanin-3) (EC 3.5.1.92),GO:0031225; GO:0005615; GO:0017159; GO:0015939; GO:0005886,anchored to membrane; extracellular space; pantetheine hydrolase activity; pantothenate metabolic process; plasma membrane,PF00795;,,,,,,,,,VNN3_MOUSE,Mus musculus (Mouse),biotin metabolic process [GO:0006768]; central nervous system development [GO:0007417]; pantothenate metabolic process [GO:0015939] comp143313_c0_seq1,1027,41.6748,0.45374337,0,0,,2.00E-43,Q8VIJ5,Bifunctional protein NCOAT (Meningioma-expressed antigen 5) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) [Includes: Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (HAT) (EC 2.3.1.48)],Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase),GO:0006044; GO:0007568; GO:0004563; GO:0005737; GO:0046060; GO:0004402; GO:0070265; GO:0010616; GO:0060051; GO:0005634; GO:0051054; GO:0010524; GO:0031343; GO:0046326; GO:0060124; GO:0032024; GO:0051901; GO:0043243; GO:0045862; GO:0006612; GO:0048545,N-acetylglucosamine metabolic process; aging; beta-N-acetylhexosaminidase activity; cytoplasm; dATP metabolic process; histone acetyltransferase activity; necrotic cell death; negative regulation of cardiac muscle adaptation; negative regulation of protein glycosylation; nucleus; positive regulation of DNA metabolic process; positive regulation of calcium ion transport into cytosol; positive regulation of cell killing; positive regulation of glucose import; positive regulation of growth hormone secretion; positive regulation of insulin secretion; positive regulation of mitochondrial depolarization; positive regulation of protein complex disassembly; positive regulation of proteolysis; protein targeting to membrane; response to steroid hormone stimulus,PF07555;,,,,,,,,,NCOAT_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; dATP metabolic process [GO:0046060]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein targeting to membrane [GO:0006612]; response to steroid hormone [GO:0048545] comp143313_c0_seq10,2382,40.7641,0.51564776,0,0,,1.00E-166,O60502,Bifunctional protein NCOAT (Meningioma-expressed antigen 5) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) [Includes: Protein O-GlcNAcase (EC 3.2.1.169) (Glycoside hydrolase O-GlcNAcase) (Hexosaminidase C) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (O-GlcNAcase) (OGA); Histone acetyltransferase (HAT) (EC 2.3.1.48)],Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (EC 3.2.1.-) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT),GO:0006044; GO:0007568; GO:0005737; GO:0046060; GO:0006516; GO:0004402; GO:0004415; GO:0070265; GO:0010616; GO:0060051; GO:0005634; GO:0051054; GO:0010524; GO:0031343; GO:0046326; GO:0060124; GO:0032024; GO:0051901; GO:0043243; GO:0045862; GO:0006612; GO:0048545,N-acetylglucosamine metabolic process; aging; cytoplasm; dATP metabolic process; glycoprotein catabolic process; histone acetyltransferase activity; hyalurononglucosaminidase activity; necrotic cell death; negative regulation of cardiac muscle adaptation; negative regulation of protein glycosylation; nucleus; positive regulation of DNA metabolic process; positive regulation of calcium ion transport into cytosol; positive regulation of cell killing; positive regulation of glucose import; positive regulation of growth hormone secretion; positive regulation of insulin secretion; positive regulation of mitochondrial depolarization; positive regulation of protein complex disassembly; positive regulation of proteolysis; protein targeting to membrane; response to steroid hormone stimulus,PF07555;,2.00E-99,CHOYP_PHUM_PHUM456250.1.1,,,,,,,NCOAT_HUMAN,Homo sapiens (Human),glycoprotein catabolic process [GO:0006516]; N-acetylglucosamine metabolic process [GO:0006044]; protein deglycosylation [GO:0006517] comp143313_c0_seq11,3512,34.4818,0.4636859,0,0,,,,,,,,,1.00E-14,CHOYP_LOC100378403.1.1,,,,,,,,, comp143313_c0_seq12,1885,36.6578,0.4062415,0,0,,2.00E-41,Q8VIJ5,Bifunctional protein NCOAT (Meningioma-expressed antigen 5) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) [Includes: Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (HAT) (EC 2.3.1.48)],Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase),GO:0006044; GO:0007568; GO:0004563; GO:0005737; GO:0046060; GO:0004402; GO:0070265; GO:0010616; GO:0060051; GO:0005634; GO:0051054; GO:0010524; GO:0031343; GO:0046326; GO:0060124; GO:0032024; GO:0051901; GO:0043243; GO:0045862; GO:0006612; GO:0048545,N-acetylglucosamine metabolic process; aging; beta-N-acetylhexosaminidase activity; cytoplasm; dATP metabolic process; histone acetyltransferase activity; necrotic cell death; negative regulation of cardiac muscle adaptation; negative regulation of protein glycosylation; nucleus; positive regulation of DNA metabolic process; positive regulation of calcium ion transport into cytosol; positive regulation of cell killing; positive regulation of glucose import; positive regulation of growth hormone secretion; positive regulation of insulin secretion; positive regulation of mitochondrial depolarization; positive regulation of protein complex disassembly; positive regulation of proteolysis; protein targeting to membrane; response to steroid hormone stimulus,PF07555;,,,,,,,,,NCOAT_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; dATP metabolic process [GO:0046060]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein targeting to membrane [GO:0006612]; response to steroid hormone [GO:0048545] comp143313_c0_seq3,2796,42.1316,0.50907884,0,0,,,,,,,,,2.00E-99,CHOYP_PHUM_PHUM456250.1.1,,,,,,,,, comp143313_c0_seq5,2936,42.2684,0.49687935,13,2,,0,O60502,Bifunctional protein NCOAT (Meningioma-expressed antigen 5) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) [Includes: Protein O-GlcNAcase (EC 3.2.1.169) (Glycoside hydrolase O-GlcNAcase) (Hexosaminidase C) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (O-GlcNAcase) (OGA); Histone acetyltransferase (HAT) (EC 2.3.1.48)],Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (EC 3.2.1.-) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT),GO:0006044; GO:0007568; GO:0005737; GO:0046060; GO:0006516; GO:0004402; GO:0004415; GO:0070265; GO:0010616; GO:0060051; GO:0005634; GO:0051054; GO:0010524; GO:0031343; GO:0046326; GO:0060124; GO:0032024; GO:0051901; GO:0043243; GO:0045862; GO:0006612; GO:0048545,N-acetylglucosamine metabolic process; aging; cytoplasm; dATP metabolic process; glycoprotein catabolic process; histone acetyltransferase activity; hyalurononglucosaminidase activity; necrotic cell death; negative regulation of cardiac muscle adaptation; negative regulation of protein glycosylation; nucleus; positive regulation of DNA metabolic process; positive regulation of calcium ion transport into cytosol; positive regulation of cell killing; positive regulation of glucose import; positive regulation of growth hormone secretion; positive regulation of insulin secretion; positive regulation of mitochondrial depolarization; positive regulation of protein complex disassembly; positive regulation of proteolysis; protein targeting to membrane; response to steroid hormone stimulus,PF07555;,5.00E-102,CHOYP_PHUM_PHUM456250.1.1,,,,,,,NCOAT_HUMAN,Homo sapiens (Human),glycoprotein catabolic process [GO:0006516]; N-acetylglucosamine metabolic process [GO:0006044]; protein deglycosylation [GO:0006517] comp143313_c0_seq6,4563,38.593,0.53026609,45,211,,8.00E-35,Q0TR53,O-GlcNAcase NagJ (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (GH84) (Hexosaminidase B) (N-acetyl-beta-glucosaminidase),O-GlcNAcase NagJ (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (GH84C) (Hexosaminidase B) (N-acetyl-beta-D-glucosaminidase),GO:0030246; GO:0007155; GO:0016798,"carbohydrate binding; cell adhesion; hydrolase activity, acting on glycosyl bonds",PF00754;PF00041;PF02838;PF07555;,,,,,,,,,OGA_CLOP1,Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A),carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517] comp143313_c0_seq9,1674,42.8315,0.41900548,0,0,,,,,,,,,7.00E-15,CHOYP_LOC100378403.1.1,,,,,,,,, comp143314_c0_seq4,2566,34.8012,0.66039659,532,818,,2.00E-41,Q3B8H3,"Transmembrane protein 11-B, mitochondrial","Transmembrane protein 11-B, mitochondrial",GO:0031305; GO:0007005,integral to mitochondrial inner membrane; mitochondrion organization,PF14972;,,,,,,,,,TM11B_XENLA,Xenopus laevis (African clawed frog),mitochondrion organization [GO:0007005] comp143316_c1_seq2,870,40.4598,0.43046414,55,289,,1.00E-16,Q1RLU1,BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1),BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1),GO:0005634; GO:0010212,nucleus; response to ionizing radiation,,,,,,,,,,BRAT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein phosphorylation [GO:0001934]; response to ionizing radiation [GO:0010212] comp143317_c0_seq1,3490,37.8797,0.54753589,203,947,,2.00E-129,A7RNG8,Coiled-coil domain-containing protein 22 homolog,Coiled-coil domain-containing protein 22 homolog,,,,,,,,,,,,CCD22_NEMVE,Nematostella vectensis (Starlet sea anemone),positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060] comp143317_c0_seq2,2768,39.4147,0.49031553,15,78,,9.00E-71,Q1RMI8,Coiled-coil domain-containing protein 22,Coiled-coil domain-containing protein 22,,,,4.00E-153,CHOYP_CCD22.1.1,1.00E-42,ruditapes_c10143,,,,,CCD22_BOVIN,Bos taurus (Bovine),cellular copper ion homeostasis [GO:0006878]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; Golgi to plasma membrane transport [GO:0006893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; protein transport [GO:0015031] comp143320_c0_seq1,4209,41.1974,0.43029149,8,7,,2.00E-113,Q8IUD2,ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2),ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2),GO:0000139; GO:0007252; GO:0008385; GO:0043522; GO:0007275; GO:0051092; GO:0042734; GO:0015031; GO:0042147,"Golgi membrane; I-kappaB phosphorylation; IkappaB kinase complex; leucine zipper domain binding; multicellular organismal development; positive regulation of NF-kappaB transcription factor activity; presynaptic membrane; protein transport; retrograde transport, endosome to Golgi",PF10174;PF09457;,2.00E-33,CHOYP_RB6I2.2.2,,,,,,,RB6I2_HUMAN,Homo sapiens (Human),"I-kappaB phosphorylation [GO:0007252]; multicellular organism development [GO:0007275]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; retrograde transport, endosome to Golgi [GO:0042147]" comp143320_c0_seq2,4227,41.0693,0.41957947,13,6,,5.00E-118,O15083,ERC protein 2,ERC protein 2,GO:0030054; GO:0005737; GO:0005856; GO:0030426; GO:0042734,cell junction; cytoplasm; cytoskeleton; growth cone; presynaptic membrane,PF10174;,,,,,,,,,ERC2_HUMAN,Homo sapiens (Human), comp143320_c0_seq3,3450,42.4928,0.3864392,0,10,,7.00E-115,Q8IUD2,ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2),ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2),GO:0000139; GO:0007252; GO:0008385; GO:0043522; GO:0007275; GO:0051092; GO:0042734; GO:0015031; GO:0042147,"Golgi membrane; I-kappaB phosphorylation; IkappaB kinase complex; leucine zipper domain binding; multicellular organismal development; positive regulation of NF-kappaB transcription factor activity; presynaptic membrane; protein transport; retrograde transport, endosome to Golgi",PF10174;PF09457;,,,,,,,,,RB6I2_HUMAN,Homo sapiens (Human),"I-kappaB phosphorylation [GO:0007252]; multicellular organism development [GO:0007275]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; retrograde transport, endosome to Golgi [GO:0042147]" comp143320_c0_seq4,3432,42.5117,0.38827103,0,0,,4.00E-119,O15083,ERC protein 2,ERC protein 2,GO:0030054; GO:0005737; GO:0005856; GO:0030426; GO:0042734,cell junction; cytoplasm; cytoskeleton; growth cone; presynaptic membrane,PF10174;,1.00E-33,CHOYP_RB6I2.2.2,,,,,,,ERC2_HUMAN,Homo sapiens (Human), comp143324_c0_seq2,2360,40.2966,0.55592193,267,453,,6.00E-101,Q28CQ7,Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2),Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2),GO:0007049; GO:0030154; GO:0000775; GO:0018024; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"cell cycle; cell differentiation; chromosome, centromeric region; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00385;PF05033;PF00856;,5.00E-88,CHOYP_SUV92.1.1,,,,,,,SUV92_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell cycle [GO:0007049]; cell differentiation [GO:0030154]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143326_c1_seq2,2044,43.1996,0.5152989,3,0,,6.00E-114,Q6A070,Protein FAM179B,Protein FAM179B,,,,3.00E-96,CHOYP_F179B.1.1,,,,,,,F179B_MOUSE,Mus musculus (Mouse), comp143326_c3_seq10,2707,44.034,0.60012453,0,0,,1.00E-06,Q61KX5,Protein CLASP-1,Protein CLASP-1,GO:0005737; GO:0005874,cytoplasm; microtubule,PF12348;PF02985;,,,,,,,,,CLAP1_CAEBR,Caenorhabditis briggsae, comp143326_c3_seq11,3624,42.4117,0.56342663,0,0,,3.00E-86,Q6A070,Protein FAM179B,Protein FAM179B,,,,9.00E-106,CHOYP_F179B.1.1,,,,,,,F179B_MOUSE,Mus musculus (Mouse), comp143326_c3_seq12,2498,43.5949,0.57854321,0,0,,3.00E-70,Q6A070,Protein FAM179B,Protein FAM179B,,,,,,,,,,,,F179B_MOUSE,Mus musculus (Mouse), comp143326_c3_seq2,3749,42.6247,0.59350473,0,0,,1.00E-84,Q9Y4F4,Protein FAM179B,Protein FAM179B,,,,9.00E-106,CHOYP_F179B.1.1,,,,,,,F179B_HUMAN,Homo sapiens (Human), comp143326_c3_seq3,3833,42.7863,0.58088822,0,0,,4.00E-86,Q6A070,Protein FAM179B,Protein FAM179B,,,,1.00E-105,CHOYP_FAM179B.2.2,,,,,,,F179B_MOUSE,Mus musculus (Mouse), comp143326_c3_seq5,2414,43.372,0.59762666,0,0,,5.00E-06,Q95YF0,Protein CLASP-1,Protein CLASP-1,GO:0005737; GO:0005874,cytoplasm; microtubule,PF12348;PF02985;,,,,,,,,,CLAP1_CAEEL,Caenorhabditis elegans,astral microtubule organization [GO:0030953]; cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; spindle elongation [GO:0051231] comp143326_c3_seq7,2623,43.8429,0.61829797,0,0,,1.00E-06,Q61KX5,Protein CLASP-1,Protein CLASP-1,GO:0005737; GO:0005874,cytoplasm; microtubule,PF12348;PF02985;,,,,,,,,,CLAP1_CAEBR,Caenorhabditis briggsae, comp143326_c3_seq9,3540,42.2316,0.57639305,0,0,,,,,,,,,9.00E-106,CHOYP_F179B.1.1,,,,,,,,, comp143327_c0_seq3,1501,36.3091,0.49202905,0,5,,2.00E-59,Q9BQ69,O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase),O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase),GO:0019213; GO:0016798; GO:0005739; GO:0005634; GO:0051725; GO:0042278; GO:0006974,"deacetylase activity; hydrolase activity, acting on glycosyl bonds; mitochondrion; nucleus; protein de-ADP-ribosylation; purine nucleoside metabolic process; response to DNA damage stimulus",PF01661;,5.00E-29,CHOYP_BRAFLDRAFT_123909.1.1,,,,,,,MACD1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] comp143328_c1_seq1,1198,44.4073,0.51289765,68,38,,4.00E-14,Q9C107,Minichromosome loss protein 1 (DNA polymerase alpha accessory factor Mcl1),Minichromosome loss protein 1 (DNA polymerase alpha accessory factor Mcl1),GO:0006281; GO:0006261; GO:0000082; GO:0005658; GO:0003682; GO:0071459; GO:0006355; GO:0006974; GO:0000723; GO:0006351,"DNA repair; DNA-dependent DNA replication; G1/S transition of mitotic cell cycle; alpha DNA polymerase:primase complex; chromatin binding; protein localization to chromosome, centromeric region; regulation of transcription, DNA-dependent; response to DNA damage stimulus; telomere maintenance; transcription, DNA-dependent",PF12894;PF12341;,8.00E-44,CHOYP_WDHD1.1.1,,,,,,,MCL1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"cellular response to DNA damage stimulus [GO:0006974]; CENP-A containing chromatin organization [GO:0061641]; chromatin silencing at centromere [GO:0030702]; DNA repair [GO:0006281]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; transcription, DNA-templated [GO:0006351]" comp143328_c2_seq1,1523,47.8661,0.4250455,0,51,,4.00E-114,O13046,WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1),WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1),GO:0003677; GO:0005737; GO:0005654,DNA binding; cytoplasm; nucleoplasm,PF08662;PF00505;PF12341;PF00400;,,,,,,,,,WDHD1_XENLA,Xenopus laevis (African clawed frog), comp143328_c2_seq2,2019,45.0223,0.40195015,130,194,,4.00E-135,P59328,WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1),WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1),GO:0003677; GO:0003723; GO:0070063; GO:0006396; GO:0003682; GO:0000775; GO:0070829; GO:0005654; GO:0033044,"DNA binding; RNA binding; RNA polymerase binding; RNA processing; chromatin binding; chromosome, centromeric region; heterochromatin maintenance; nucleoplasm; regulation of chromosome organization",PF12894;PF00505;PF12341;PF00400;,,,,,,,,,WDHD1_MOUSE,Mus musculus (Mouse),heterochromatin maintenance [GO:0070829]; regulation of chromosome organization [GO:0033044]; RNA processing [GO:0006396] comp143329_c0_seq1,2809,50.0534,0.43367285,97,39,,3.00E-175,Q9Y5Z7,Host cell factor 2 (HCF-2) (C2 factor),Host cell factor 2 (HCF-2) (C2 factor),GO:0005737; GO:0000122; GO:0005634; GO:0003713; GO:0016032,cytoplasm; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription coactivator activity; viral process,PF01344;,,,,,,,,,HCFC2_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; viral process [GO:0016032] comp143329_c0_seq2,2773,50.3426,0.45699794,72,13,,0,P51610,Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],GO:0071339; GO:0070688; GO:0048188; GO:0007049; GO:0003682; GO:0043984; GO:0043981; GO:0043982; GO:0000123; GO:0005739; GO:0019048; GO:0000122; GO:0043025; GO:0045787; GO:0010628; GO:0050821; GO:0043254; GO:0019046; GO:0003700; GO:0003713; GO:0006366,MLL1 complex; MLL5-L complex; Set1C/COMPASS complex; cell cycle; chromatin binding; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase complex; mitochondrion; modulation by virus of host morphology or physiology; negative regulation of transcription from RNA polymerase II promoter; neuronal cell body; positive regulation of cell cycle; positive regulation of gene expression; protein stabilization; regulation of protein complex assembly; release from viral latency; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription from RNA polymerase II promoter,PF01344;,0,CHOYP_BRAFLDRAFT_122422.2.2,,,,,,,HCFC1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; mitochondrion organization [GO:0007005]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]; transcription from RNA polymerase II promoter [GO:0006366]" comp143331_c1_seq4,634,43.5331,0.40183615,3,0,,1.00E-38,Q3ZLR7,Transcription factor SPT20 homolog-like 1,Transcription factor SPT20 homolog-like 1,GO:0000124; GO:0003712,SAGA complex; transcription cofactor activity,PF12090;,,,,,,,,,F48B1_HUMAN,Homo sapiens (Human), comp143331_c1_seq5,1263,44.5764,0.36748854,0,0,,1.00E-51,Q7TT00,Transcription factor SPT20 homolog (p38-interacting protein) (p38IP),Transcription factor SPT20 homolog (p38-interacting protein) (p38IP),GO:0000124; GO:0007369; GO:0003712,SAGA complex; gastrulation; transcription cofactor activity,PF12090;,,,,,,,,,FA48A_MOUSE,Mus musculus (Mouse),gastrulation [GO:0007369]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948] comp143331_c1_seq6,1821,45.6892,0.35192902,43,115,,,,,,,,,9.00E-58,CHOYP_ISCW_ISCW017342.1.1,,,,,,,,, comp143333_c0_seq1,3597,41.1732,0.39643163,2,37,,3.00E-159,Q5REG1,Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3),Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3),GO:0003723; GO:0006396; GO:0005737; GO:0016607; GO:0000166,RNA binding; RNA processing; cytoplasm; nuclear speck; nucleotide binding,PF05391;PF00076;,1.00E-46,CHOYP_CBPC1.1.1,,,,,,,SART3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp143333_c0_seq2,3618,41.2383,0.39298017,0,0,,3.00E-13,P15771,Nucleolin (Protein C23),Nucleolin (Protein C23),GO:0003677; GO:0003723; GO:0005730; GO:0000166,DNA binding; RNA binding; nucleolus; nucleotide binding,PF00076;,,,,,,,,,NUCL_CHICK,Gallus gallus (Chicken), comp143333_c0_seq3,3493,41.1394,0.3676734,0,0,,3.00E-159,Q5REG1,Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3),Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3),GO:0003723; GO:0006396; GO:0005737; GO:0016607; GO:0000166,RNA binding; RNA processing; cytoplasm; nuclear speck; nucleotide binding,PF05391;PF00076;,1.00E-46,CHOYP_CBPC1.1.1,2.00E-36,ruditapes_c10530,,,,,SART3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp143333_c0_seq4,3605,41.1096,0.37071186,0,7,,3.00E-14,Q6Z1C0,Nucleolin 1 (Protein NUCLEOLIN LIKE 1),Nucleolin 1 (Protein NUCLEOLIN LIKE 1),GO:0003723; GO:0005730; GO:0000166; GO:0006364,RNA binding; nucleolus; nucleotide binding; rRNA processing,PF00076;,,,,,,,,,NUCL1_ORYSJ,Oryza sativa subsp. japonica (Rice),rRNA processing [GO:0006364] comp143334_c0_seq1,4946,37.9701,0.64617091,2529,4416,,9.00E-67,P48964,M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A),M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A),GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0035335; GO:0004725; GO:0009314,cell division; cytoplasm; mitosis; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; response to radiation,PF06617;PF00581;,1.00E-60,CHOYP_LOC100711118.1.1,,,,,,,MPIP1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cellular response to UV [GO:0034644]; mitotic nuclear division [GO:0007067]; response to radiation [GO:0009314] comp143335_c0_seq1,1877,36.8141,0.51936753,245,1215,,4.00E-24,Q568R1,Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55),Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55),,,PF09745;,5.00E-30,CHOYP_NSRP1.1.1,5.00E-40,ruditapes_c18812,,,,,NSRP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143336_c0_seq7,813,38.9914,0.850576,0,0,,1.00E-05,P29553,"Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]","Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]",GO:0007254; GO:0000187; GO:0000185; GO:0006919; GO:0060555; GO:0071230; GO:0071316; GO:0002439; GO:0050830; GO:0048566; GO:0060664; GO:0009897; GO:0030198; GO:0005615; GO:0008625; GO:0006006; GO:0006959; GO:0005887; GO:0050901; GO:0031663; GO:0045121; GO:0070265; GO:0010693; GO:0061048; GO:0002740; GO:2001240; GO:0046325; GO:0044130; GO:0032715; GO:0050995; GO:0045668; GO:0043242; GO:0000122; GO:0045071; GO:0009887; GO:0030316; GO:0001891; GO:0043123; GO:0046330; GO:0043507; GO:0042346; GO:0051092; GO:0051533; GO:0043065; GO:0060559; GO:2000343; GO:0045080; GO:0002876; GO:0050715; GO:0031622; GO:0051798; GO:0034116; GO:0002925; GO:0032729; GO:0032755; GO:0045416; GO:0051044; GO:0045429; GO:0045672; GO:0033138; GO:0071803; GO:0043243; GO:0051897; GO:2000010; GO:0048661; GO:0045944; GO:0045994; GO:0060557; GO:0000060; GO:0043491; GO:0032800; GO:0055037; GO:0060693; GO:0051023; GO:0050796; GO:0051384; GO:0009615; GO:0030730; GO:0044212; GO:0006927; GO:0033209,"JNK cascade; activation of MAPK activity; activation of MAPKKK activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of necroptosis by extracellular signals; cellular response to amino acid stimulus; cellular response to nicotine; chronic inflammatory response to antigenic stimulus; defense response to Gram-positive bacterium; embryonic digestive tract development; epithelial cell proliferation involved in salivary gland morphogenesis; external side of plasma membrane; extracellular matrix organization; extracellular space; extrinsic apoptotic signaling pathway via death domain receptors; glucose metabolic process; humoral immune response; integral to plasma membrane; leukocyte tethering or rolling; lipopolysaccharide-mediated signaling pathway; membrane raft; necrotic cell death; negative regulation of alkaline phosphatase activity; negative regulation of branching involved in lung morphogenesis; negative regulation of cytokine secretion involved in immune response; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of glucose import; negative regulation of growth of symbiont in host; negative regulation of interleukin-6 production; negative regulation of lipid catabolic process; negative regulation of osteoblast differentiation; negative regulation of protein complex disassembly; negative regulation of transcription from RNA polymerase II promoter; negative regulation of viral genome replication; organ morphogenesis; osteoclast differentiation; phagocytic cup; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of NF-kappaB import into nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of NFAT protein import into nucleus; positive regulation of apoptotic process; positive regulation of calcidiol 1-monooxygenase activity; positive regulation of chemokine (C-X-C motif) ligand 2 production; positive regulation of chemokine biosynthetic process; positive regulation of chronic inflammatory response to antigenic stimulus; positive regulation of cytokine secretion; positive regulation of fever generation; positive regulation of hair follicle development; positive regulation of heterotypic cell-cell adhesion; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of interferon-gamma production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 biosynthetic process; positive regulation of membrane protein ectodomain proteolysis; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of podosome assembly; positive regulation of protein complex disassembly; positive regulation of protein kinase B signaling cascade; positive regulation of protein localization to cell surface; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translational initiation by iron; positive regulation of vitamin D biosynthetic process; protein import into nucleus, translocation; protein kinase B signaling cascade; receptor biosynthetic process; recycling endosome; regulation of branching involved in salivary gland morphogenesis; regulation of immunoglobulin secretion; regulation of insulin secretion; response to glucocorticoid stimulus; response to virus; sequestering of triglyceride; transcription regulatory region DNA binding; transformed cell apoptotic process; tumor necrosis factor-mediated signaling pathway",PF00229;,,,,,,,,,TNFA_HORSE,Equus caballus (Horse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cortical actin cytoskeleton organization [GO:0030866]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; establishment of protein localization to plasma membrane [GO:0090002]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of glucose import [GO:0046325]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of fever generation [GO:0031622]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; protein import into nucleus, translocation [GO:0000060]; protein kinase B signaling [GO:0043491]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; response to glucocorticoid [GO:0051384]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp143338_c0_seq1,901,42.5083,0.34606784,4,0,,,,,,,,,4.00E-40,CHOYP_PDE11.1.3,,,,,,,,, comp143338_c0_seq2,3458,37.9121,0.40806651,27,0,,0,Q9VFI9,"cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (DmPDE5/6) (DmPDE6)","cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (DmPDE5/6) (DmPDE6)",GO:0047555; GO:0016324; GO:0046068; GO:0046872; GO:0032240; GO:0007165,"3',5'-cyclic-GMP phosphodiesterase activity; apical plasma membrane; cGMP metabolic process; metal ion binding; negative regulation of nucleobase-containing compound transport; signal transduction",PF01590;PF00233;,,,,,,,,,PDE6_DROME,Drosophila melanogaster (Fruit fly),cGMP metabolic process [GO:0046068]; negative regulation of nucleobase-containing compound transport [GO:0032240]; signal transduction [GO:0007165] comp143338_c0_seq3,1149,40.9051,0.39854111,8,0,,2.00E-27,Q64338,"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17)","Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17)",GO:0048101; GO:0004117; GO:0005929; GO:0046872; GO:0051592; GO:0007608; GO:0007165,"calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; cilium; metal ion binding; response to calcium ion; sensory perception of smell; signal transduction",PF00233;PF08499;,6.00E-14,CHOYP_TRIADDRAFT_21752.1.1,,,,,,,PDE1C_MOUSE,Mus musculus (Mouse),response to calcium ion [GO:0051592]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165] comp143338_c0_seq4,3447,37.9751,0.40759588,39,0,,0,B4JXX2,"cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35)","cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35)",GO:0047555; GO:0046068; GO:0016020; GO:0046872; GO:0005886; GO:0007165,"3',5'-cyclic-GMP phosphodiesterase activity; cGMP metabolic process; membrane; metal ion binding; plasma membrane; signal transduction",PF01590;PF00233;,0,CHOYP_LOC100369315.2.2,,,,,,,PDE6_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi),cGMP metabolic process [GO:0046068]; signal transduction [GO:0007165] comp143339_c1_seq2,3415,27.2621,0.47368133,369,949,,2.00E-11,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,7.00E-31,CHOYP_LOC100490320.2.2,3.00E-34,ruditapes_c17285,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143339_c2_seq3,1114,46.3196,0.57076228,0,0,,,,,,,,,5.00E-52,CHOYP_CAC1D.1.1,,,,,,,,, comp143339_c2_seq4,1021,39.9608,0.54048129,0,0,,5.00E-155,Q25452,Muscle calcium channel subunit alpha-1 (MDL-alpha-1),Muscle calcium channel subunit alpha-1 (MDL-alpha-1),GO:0046872; GO:0005245; GO:0005891,metal ion binding; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08763;PF16905;PF00520;,,,,,,,,,CAC1M_MUSDO,Musca domestica (House fly), comp143339_c2_seq7,2117,43.7884,0.56219103,0,0,,0,P27732,"Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)","Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)",GO:0046872; GO:0051924; GO:0086007; GO:0005891,metal ion binding; regulation of calcium ion transport; voltage-gated calcium channel activity involved in regulation of cardiac muscle cell action potential; voltage-gated calcium channel complex,PF08763;PF16885;PF16905;PF00520;,0,CHOYP_CAC1D.1.1,,,,,,,CAC1D_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; divalent metal ion transport [GO:0070838]; heart development [GO:0007507]; membrane depolarization during action potential [GO:0086010]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; memory [GO:0007613]; positive regulation of CREB transcription factor activity [GO:0032793]; regulation of calcium ion transport [GO:0051924] comp143339_c2_seq9,2415,44.5549,0.59263978,0,0,,0,P22002,"Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Rat brain class C) (RBC) (Voltage-gated calcium channel subunit alpha Cav1.2)","Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Rat brain class C) (RBC) (Voltage-gated calcium channel subunit alpha Cav1.2)",GO:0030315; GO:0030018; GO:0070509; GO:0030425; GO:0008331; GO:0046872; GO:0043025; GO:0014069; GO:0005891,T-tubule; Z disc; calcium ion import; dendrite; high voltage-gated calcium channel activity; metal ion binding; neuronal cell body; postsynaptic density; voltage-gated calcium channel complex,PF08763;PF16885;PF16905;PF00520;,4.00E-20,CHOYP_LOC100647135.2.2,,,,,,,CAC1C_RAT,Rattus norvegicus (Rat),calcium ion import [GO:0070509]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport [GO:0006816]; cardiac conduction [GO:0061337]; cardiac muscle cell action potential involved in contraction [GO:0086002]; membrane depolarization during action potential [GO:0086010]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911] comp143340_c0_seq1,3251,33.5897,0.49439194,210,573,,0,Q2KJ25,26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5),26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5),GO:0022624,proteasome accessory complex,PF01399;,0,CHOYP_BRAFLDRAFT_113849.1.1,3.00E-64,ruditapes2_c3542,,,,,PSD12_BOVIN,Bos taurus (Bovine),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp143340_c0_seq2,3252,33.7023,0.51198673,93,24,,0,Q2KJ25,26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5),26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5),GO:0022624,proteasome accessory complex,PF01399;,0,CHOYP_BRAFLDRAFT_113849.1.1,,,,,,,PSD12_BOVIN,Bos taurus (Bovine),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp143342_c0_seq1,4418,42.8022,0.56631686,257,12,,0,Q8TBY9,WD repeat-containing protein 66,WD repeat-containing protein 66,GO:0005509,calcium ion binding,PF00400;,0,CHOYP_LOC100377751.1.1,,,,,,,WDR66_HUMAN,Homo sapiens (Human), comp143342_c0_seq2,4444,42.6643,0.56676139,141,12,,0,Q8TBY9,WD repeat-containing protein 66,WD repeat-containing protein 66,GO:0005509,calcium ion binding,PF00400;,0,CHOYP_LOC100377751.1.1,,,,,,,WDR66_HUMAN,Homo sapiens (Human), comp143345_c0_seq1,3407,33.1083,0.40629998,390,3247,,3.00E-73,Q99437,V-type proton ATPase 21 kDa proteolipid subunit (V-ATPase 21 kDa proteolipid subunit) (Vacuolar proton pump 21 kDa proteolipid subunit) (hATPL),V-type proton ATPase 21 kDa proteolipid subunit (V-ATPase 21 kDa proteolipid subunit) (Vacuolar proton pump 21 kDa proteolipid subunit) (hATPL),GO:0015991; GO:0006879; GO:0010008; GO:0015078; GO:0008286; GO:0016021; GO:0051701; GO:0030670; GO:0090382; GO:0015992; GO:0033179; GO:0033572; GO:0055085; GO:0005215; GO:0005774,"ATP hydrolysis coupled proton transport; cellular iron ion homeostasis; endosome membrane; hydrogen ion transmembrane transporter activity; insulin receptor signaling pathway; integral to membrane; interaction with host; phagocytic vesicle membrane; phagosome maturation; proton transport; proton-transporting V-type ATPase, V0 domain; transferrin transport; transmembrane transport; transporter activity; vacuolar membrane",PF00137;,1.00E-60,CHOYP_BRAFLDRAFT_114064.1.1,,,,,,,VATO_HUMAN,Homo sapiens (Human),ATP hydrolysis coupled proton transport [GO:0015991]; insulin receptor signaling pathway [GO:0008286]; ion transmembrane transport [GO:0034220]; phagosome acidification [GO:0090383]; proton transport [GO:0015992]; regulation of macroautophagy [GO:0016241]; transferrin transport [GO:0033572]; vacuolar acidification [GO:0007035] comp143345_c0_seq3,3435,35.837,0.55883628,28825,823,,1.00E-24,Q8BSN3,Coiled-coil domain-containing protein 151,Coiled-coil domain-containing protein 151,,,,,,,,,,,,CC151_MOUSE,Mus musculus (Mouse),cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium assembly [GO:1902017] comp143346_c0_seq1,1624,35.0369,0.36848087,2308,8713,,2.00E-25,A4QNF3,Reactive oxygen species modulator 1 (ROS modulator 1) (Protein MGR2 homolog),Reactive oxygen species modulator 1 (ROS modulator 1) (Protein MGR2 homolog),GO:0034614; GO:0042742; GO:0016021; GO:0005743; GO:0005739; GO:0008284; GO:2000379; GO:0001302,cellular response to reactive oxygen species; defense response to bacterium; integral to membrane; mitochondrial inner membrane; mitochondrion; positive regulation of cell proliferation; positive regulation of reactive oxygen species metabolic process; replicative cell aging,PF10247;,4.00E-11,CHOYP_LOC100876106.1.1,3.00E-30,ruditapes_c903,,,,,ROMO1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to reactive oxygen species [GO:0034614]; defense response to bacterium [GO:0042742]; positive regulation of cell proliferation [GO:0008284]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; replicative cell aging [GO:0001302] comp143346_c5_seq1,2082,37.8963,0.32315457,999,6452,,6.00E-179,Q6P819,Cell differentiation protein RCD1 homolog (Rcd-1),Cell differentiation protein RCD1 homolog (Rcd-1),GO:0030014; GO:0000932; GO:0031047; GO:0033147; GO:0005634; GO:2000327; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; cytoplasmic mRNA processing body; gene silencing by RNA; negative regulation of intracellular estrogen receptor signaling pathway; nucleus; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",,5.00E-151,CHOYP_LOC100367949.1.3,,,,,,,RCD1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"gene silencing by RNA [GO:0031047]; mRNA catabolic process [GO:0006402]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of translation [GO:0017148]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143346_c5_seq3,309,31.068,0.13507767,0,1,,,,,,,,,,,4.00E-13,ruditapes2_c1220,,,,,,, comp143346_c5_seq4,655,30.3817,0.26655893,575,939,,,,,,,,,,,3.00E-18,ruditapes_c28309,,,,,,, comp143348_c0_seq1,2027,35.4218,0.56923667,253,937,,5.00E-84,Q58DM4,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 (EC 1.14.11.33) (Alkylated DNA repair protein alkB homolog 2) (DNA oxidative demethylase ALKBH2),DNA oxidative demethylase ALKBH2 (EC 1.14.11.33) (Alkylated DNA repair protein alkB homolog 2) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2),GO:0006307; GO:0043734; GO:0051747; GO:0008198; GO:0005634; GO:0035511,DNA dealkylation involved in DNA repair; DNA-N1-methyladenine dioxygenase activity; cytosine C-5 DNA demethylase activity; ferrous iron binding; nucleus; oxidative DNA demethylation,PF13532;,,,,,,,,,ALKB2_BOVIN,Bos taurus (Bovine),DNA dealkylation involved in DNA repair [GO:0006307]; oxidative DNA demethylation [GO:0035511] comp143349_c0_seq1,3081,36.222,0.49801575,445,2378,,9.00E-122,Q3ZBZ8,Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop),Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop),GO:0005737; GO:0005634,cytoplasm; nucleus,PF13414;PF13181;,1.00E-91,CHOYP_STIP1.1.2,,,,,,,STIP1_BOVIN,Bos taurus (Bovine), comp143350_c0_seq1,1862,31.3641,0.28750008,147,2679,,7.00E-08,Q2TAP8,Coiled-coil-helix-coiled-coil-helix domain-containing protein 7,Coiled-coil-helix-coiled-coil-helix domain-containing protein 7,GO:0005758,mitochondrial intermembrane space,,,,,,,,,,CHCH7_XENLA,Xenopus laevis (African clawed frog), comp143353_c0_seq8,1725,33.971,0.16183784,0,0,,,,,,,,,,,2.00E-14,ruditapes_c1304,,,,,,, comp143354_c0_seq1,1450,41.3793,0.47055623,165,1343,,5.00E-115,P70541,Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma),Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma),GO:0005851; GO:0005085; GO:0032057; GO:0016779; GO:0014003; GO:0009749; GO:0009408; GO:0043434; GO:0003743; GO:0006413,eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor activity; negative regulation of translational initiation in response to stress; nucleotidyltransferase activity; oligodendrocyte development; response to glucose stimulus; response to heat; response to peptide hormone stimulus; translation initiation factor activity; translational initiation,PF00483;,7.00E-27,CHOYP_LOC100375678.1.1,4.00E-135,ruditapes_c11299,,,,,EI2BG_RAT,Rattus norvegicus (Rat),cellular response to stimulus [GO:0051716]; hippocampus development [GO:0021766]; oligodendrocyte development [GO:0014003]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translation [GO:0006412]; translational initiation [GO:0006413] comp143357_c0_seq1,2529,40.5694,0.52156194,9,93,,7.00E-69,Q04199,Chromatin assembly factor 1 subunit p60 (CAF-1 60 kDa subunit),Chromatin assembly factor 1 subunit p60 (CAF-1 60 kDa subunit),GO:0033186; GO:0006335; GO:0000775; GO:0005829; GO:0005634,"CAF-1 complex; DNA replication-dependent nucleosome assembly; chromosome, centromeric region; cytosol; nucleus",PF12894;PF00400;,4.00E-71,CHOYP_CHAF1B.1.1,,,,,,,CAC2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),DNA replication-dependent nucleosome assembly [GO:0006335] comp143357_c0_seq2,2811,40.1992,0.51255659,120,417,,1.00E-152,Q9D0N7,Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60),Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60),GO:0033186; GO:0006281; GO:0006260; GO:0007049; GO:0031497; GO:0005829; GO:0005654; GO:0006355; GO:0006351,"CAF-1 complex; DNA repair; DNA replication; cell cycle; chromatin assembly; cytosol; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF15512;PF00400;,,,,,,,,,CAF1B_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent nucleosome assembly [GO:0006335]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nucleosome assembly [GO:0006334]; positive regulation of defense response to virus by host [GO:0002230]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; xenophagy [GO:0098792]" comp143358_c0_seq2,407,48.1572,0.64693837,12,17,,1.00E-12,Q9NJ15,Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase PC6-like) (aPC6),Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase PC6-like) (aPC6),GO:0005576; GO:0016021; GO:0005886; GO:0006508; GO:0004252,extracellular region; integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,,,,,,,,,PCSK5_BRACL,Branchiostoma californiense (California lancelet) (Amphioxus), comp143358_c0_seq4,549,42.4408,0.58546423,0,0,,8.00E-28,Q78EH2,Proprotein convertase subtilisin/kexin type 4 (PC4) (EC 3.4.21.-) (KEX2-like endoprotease 3) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3),Proprotein convertase subtilisin/kexin type 4 (PC4) (EC 3.4.21.-) (KEX2-like endoprotease 3) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3),GO:0006508; GO:0004252,proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,,,,,,,,,PCSK4_RAT,Rattus norvegicus (Rat),acrosome reaction [GO:0007340]; binding of sperm to zona pellucida [GO:0007339]; fertilization [GO:0009566]; protein processing [GO:0016485]; reproductive process [GO:0022414]; sperm capacitation [GO:0048240] comp143358_c0_seq5,390,48.2051,0.62403511,0,6,,1.00E-06,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp143358_c0_seq6,718,45.6825,0.46203076,6,17,,3.00E-44,P30432,Furin-like protease 2 (Furin-2) (EC 3.4.21.75),Furin-like protease 2 (Furin-2) (EC 3.4.21.75),GO:0016021; GO:0005886; GO:0006508; GO:0004252,integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity,PF14843;PF01483;PF00082;PF16470;,,,8.00E-14,ruditapes_c15836,,,,,FUR2_DROME,Drosophila melanogaster (Fruit fly),negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906] comp143358_c1_seq2,2154,37.2331,0.87110795,0,0,,2.00E-08,Q9BH10,Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2],Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2],GO:0005794; GO:0007339; GO:0005783; GO:0031012; GO:0016021; GO:0006886; GO:0005771; GO:0005886; GO:0060468; GO:0005578; GO:0030141,Golgi apparatus; binding of sperm to zona pellucida; endoplasmic reticulum; extracellular matrix; integral to membrane; intracellular protein transport; multivesicular body; plasma membrane; prevention of polyspermy; proteinaceous extracellular matrix; secretory granule,PF00100;,,,,,,,,,ZP2_BOVIN,Bos taurus (Bovine),binding of sperm to zona pellucida [GO:0007339]; intracellular protein transport [GO:0006886]; prevention of polyspermy [GO:0060468] comp143358_c1_seq3,2147,36.9818,0.87228445,0,0,,8.00E-15,Q29RU2,Oncoprotein-induced transcript 3 protein,Oncoprotein-induced transcript 3 protein,GO:0005509; GO:0005635,calcium ion binding; nuclear envelope,PF00100;,,,,,,,,,OIT3_BOVIN,Bos taurus (Bovine), comp143358_c2_seq3,1358,44.0353,0.74228534,54,67,,2.00E-142,P63239,Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1),Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1),GO:0005794; GO:0005788; GO:0005615; GO:0043043; GO:0016486; GO:0006508; GO:0034774; GO:0004252; GO:0030133,Golgi apparatus; endoplasmic reticulum lumen; extracellular space; peptide biosynthetic process; peptide hormone processing; proteolysis; secretory granule lumen; serine-type endopeptidase activity; transport vesicle,PF01483;PF00082;PF12177;PF16470;,7.00E-115,CHOYP_AFURIN2.1.1,,,,,,,NEC1_MOUSE,Mus musculus (Mouse),nerve growth factor processing [GO:0032455]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; regulation of insulin secretion [GO:0050796] comp143359_c0_seq10,920,42.8261,0.71417578,0,0,,6.00E-83,Q9P2S5,WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),GO:0005813; GO:0005737,centrosome; cytoplasm,PF12894;,,,,,,,,,WRP73_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp143359_c0_seq2,1760,43.1818,0.55046941,6,0,,1.00E-09,Q9UUG8,Transcriptional repressor tup12,Transcriptional repressor tup12,GO:0043156; GO:0006342; GO:0005829; GO:0042393; GO:0045014; GO:0000122; GO:0000790; GO:0043234; GO:0003714; GO:0006351,"chromatin remodeling in response to cation stress; chromatin silencing; cytosol; histone binding; negative regulation of transcription by glucose; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein complex; transcription corepressor activity; transcription, DNA-dependent",PF08581;PF00400;,1.00E-43,CHOYP_LOC100368359.2.2,,,,,,,TUP12_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling in response to cation stress [GO:0043156]; chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp143359_c0_seq3,1768,43.2692,0.54598783,11,2,,9.00E-165,Q9JM98,WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),GO:0005813; GO:0005737,centrosome; cytoplasm,PF00400;,,,,,,,,,WRP73_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp143359_c0_seq7,1092,44.1392,0.64266375,0,0,,,,,,,,,6.00E-39,CHOYP_LOC100368359.2.2,,,,,,,,, comp143360_c0_seq2,2433,39.8685,0.53511579,112,33,,,,,,,,,4.00E-171,CHOYP_BRAFLDRAFT_128345.1.1,,,,,,,,, comp143362_c0_seq2,2420,43.3058,0.50860041,41,144,,0,Q6NY74,Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1),Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1),GO:0003677; GO:0006260; GO:0007507; GO:0046872; GO:0005634,DNA binding; DNA replication; heart development; metal ion binding; nucleus,PF04057;PF08646;PF16900;PF01336;,1.00E-121,CHOYP_RFA1.1.1,,,9.00E-65,AM859331.p.cg.6,9,,RFA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; heart development [GO:0007507] comp143363_c0_seq1,3250,45.6308,0.51671846,46,57,,6.00E-169,B5X2S3,Actin-related protein 8,Actin-related protein 8,GO:0005524; GO:0006310; GO:0006281; GO:0031011; GO:0051301; GO:0006338; GO:0007067; GO:0006355; GO:0006351,"ATP binding; DNA recombination; DNA repair; Ino80 complex; cell division; chromatin remodeling; mitosis; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00022;,7.00E-37,CHOYP_ARP8.1.1,,,,,,,ARP8_SALSA,Salmo salar (Atlantic salmon),"cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143363_c0_seq2,3284,45.8892,0.55788453,62,47,,4.00E-176,Q8R2S9,Actin-related protein 8,Actin-related protein 8,GO:0005524; GO:0006310; GO:0006281; GO:0031011; GO:0051301; GO:0006338; GO:0007067; GO:0006355; GO:0006351,"ATP binding; DNA recombination; DNA repair; Ino80 complex; cell division; chromatin remodeling; mitosis; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00022;,7.00E-37,CHOYP_ARP8.1.1,,,,,,,ARP8_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143369_c0_seq1,3187,33.1032,0.67624885,1135,10431,,0,Q9GR88,Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1),Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1),GO:0005737; GO:0016149,"cytoplasm; translation release factor activity, codon specific",PF03463;PF03464;PF03465;,0,CHOYP_ERF1.1.1,1.00E-133,ruditapes_c30399,,,,,ERF1_POLMI,Polyandrocarpa misakiensis (Tunicate), comp143370_c0_seq2,1697,43.076,0.33086032,7,134,,2.00E-93,Q8BTY8,Sec1 family domain-containing protein 2 (Neuronal Sec1) (Syntaxin-binding protein 1-like 1),Sec1 family domain-containing protein 2 (Neuronal Sec1) (Syntaxin-binding protein 1-like 1),GO:0015031; GO:0006904,protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SCFD2_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp143370_c0_seq4,834,44.1247,0.42208143,1,28,,7.00E-50,Q8WU76,Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1-like 1),Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1-like 1),GO:0015031; GO:0006904,protein transport; vesicle docking involved in exocytosis,PF00995;,,,,,,,,,SCFD2_HUMAN,Homo sapiens (Human),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp143374_c0_seq1,1625,39.5692,0.33541593,934,5936,,5.00E-58,Q5E946,Protein DJ-1 (EC 3.4.-.-) (Parkinson disease protein 7 homolog),Protein deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (Parkinson disease protein 7 homolog),GO:0006914; GO:0070301; GO:0006954; GO:0003729; GO:0005739; GO:0007005; GO:0060548; GO:2001237; GO:0043524; GO:0032091; GO:0005634; GO:0008233; GO:0004601; GO:2000277; GO:0042803; GO:0050821; GO:0006508; GO:0060765; GO:0050727; GO:0043523; GO:0007338,autophagy; cellular response to hydrogen peroxide; inflammatory response; mRNA binding; mitochondrion; mitochondrion organization; negative regulation of cell death; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of neuron apoptotic process; negative regulation of protein binding; nucleus; peptidase activity; peroxidase activity; positive regulation of oxidative phosphorylation uncoupler activity; protein homodimerization activity; protein stabilization; proteolysis; regulation of androgen receptor signaling pathway; regulation of inflammatory response; regulation of neuron apoptotic process; single fertilization,PF01965;,1.00E-17,CHOYP_BRAFLDRAFT_94906.1.1,6.00E-45,ruditapes_c23105,,,,,PARK7_BOVIN,Bos taurus (Bovine),"adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; mitochondrion organization [GO:0007005]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; single fertilization [GO:0007338]" comp143376_c0_seq2,2759,34.2515,0.42578297,100,532,,,,,,,,,,,5.00E-17,ruditapes_c12725,,,,,,, comp143376_c0_seq3,2790,34.0502,0.42629835,86,299,,6.00E-29,P52815,"39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2)","39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2)",GO:0003723; GO:0005762; GO:0045893; GO:0003735; GO:0006390; GO:0006412,"RNA binding; mitochondrial large ribosomal subunit; positive regulation of transcription, DNA-dependent; structural constituent of ribosome; transcription from mitochondrial promoter; translation",PF00542;PF16320;,,,,,,,,,RM12_HUMAN,Homo sapiens (Human),"mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription from mitochondrial promoter [GO:0006390]" comp143377_c0_seq2,3843,45.9797,0.62101599,5,0,,1.00E-36,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,5.00E-21,CHOYP_DGRI_GH23100.1.1,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp143377_c0_seq3,2866,46.0572,0.5404771,0,0,,2.00E-40,Q08180,Irregular chiasm C-roughest protein (Protein IRREC),Irregular chiasm C-roughest protein (Protein IRREC),GO:0045177; GO:0005913; GO:0046667; GO:0007156; GO:0016021; GO:0046331; GO:0007520; GO:0005886; GO:0016202,apical part of cell; cell-cell adherens junction; compound eye retinal cell programmed cell death; homophilic cell adhesion; integral to membrane; lateral inhibition; myoblast fusion; plasma membrane; regulation of striated muscle tissue development,PF08205;PF07679;PF13895;,,,,,,,,,ICCR_DROME,Drosophila melanogaster (Fruit fly),axonogenesis [GO:0007409]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lateral inhibition [GO:0046331]; myoblast fusion [GO:0007520]; regulation of striated muscle tissue development [GO:0016202]; retinal cell programmed cell death [GO:0046666] comp143377_c0_seq4,3778,46.0826,0.61891911,6,6,,5.00E-122,Q9R044,Nephrin (Renal glomerulus-specific cell adhesion receptor),Nephrin (Renal glomerulus-specific cell adhesion receptor),GO:0007155; GO:0003094; GO:0016021; GO:0045121; GO:0007517; GO:0005886; GO:0043234; GO:0036057,cell adhesion; glomerular filtration; integral to membrane; membrane raft; muscle organ development; plasma membrane; protein complex; slit diaphragm,PF08205;PF00041;,5.00E-21,CHOYP_DGRI_GH23100.1.1,,,,,,,NPHN_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155]; glomerular filtration [GO:0003094]; muscle organ development [GO:0007517] comp143377_c0_seq5,2931,45.9229,0.5380971,0,0,,1.00E-84,O60500,Nephrin (Renal glomerulus-specific cell adhesion receptor),Nephrin (Renal glomerulus-specific cell adhesion receptor),GO:0007254; GO:0007155; GO:0042995; GO:0007588; GO:0032836; GO:0072015; GO:0005887; GO:0007520; GO:0030838; GO:0044062; GO:0007519; GO:0036057,JNK cascade; cell adhesion; cell projection; excretion; glomerular basement membrane development; glomerular visceral epithelial cell development; integral to plasma membrane; myoblast fusion; positive regulation of actin filament polymerization; regulation of excretion; skeletal muscle tissue development; slit diaphragm,PF08205;PF00041;PF07686;,,,,,,,,,NPHN_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; excretion [GO:0007588]; glomerular basement membrane development [GO:0032836]; glomerular visceral epithelial cell development [GO:0072015]; JNK cascade [GO:0007254]; myoblast fusion [GO:0007520]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to synapse [GO:0035418]; regulation of excretion [GO:0044062]; skeletal muscle tissue development [GO:0007519] comp143377_c0_seq6,1171,43.1255,0.42507995,0,0,,6.00E-09,Q9JI59,Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322),Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322),GO:0016021; GO:0007162; GO:0005886; GO:0005923,integral to membrane; negative regulation of cell adhesion; plasma membrane; tight junction,PF07686;,,,,,,,,,JAM2_MOUSE,Mus musculus (Mouse),negative regulation of cell adhesion [GO:0007162] comp143380_c0_seq1,1249,44.7558,1.01554171,5,1088,female>male,1.00E-28,O88281,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF12662;PF07645;PF00053;,,,,,,,,,MEGF6_RAT,Rattus norvegicus (Rat), comp143382_c0_seq1,3489,41.9891,0.54408753,0,0,,0,Q8K2G4,Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1),Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1),GO:0034464; GO:0007420; GO:0005813; GO:0035085; GO:0036064; GO:0060170; GO:0001654; GO:0045444; GO:0007507; GO:0060173; GO:0005634; GO:0060021; GO:0008104; GO:0007224,BBSome; brain development; centrosome; cilium axoneme; cilium basal body; cilium membrane; eye development; fat cell differentiation; heart development; limb development; nucleus; palate development; protein localization; smoothened signaling pathway,,,,,,,,,,BBS7_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cilium assembly [GO:0042384]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; nonmotile primary cilium assembly [GO:0035058]; palate development [GO:0060021]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224] comp143382_c0_seq2,2063,41.2506,0.62784153,1,0,,,,,,,,,,,3.00E-132,ruditapes_c24972,,,,,,, comp143382_c0_seq3,3537,41.9282,0.53816103,0,0,,,,,,,,,0,CHOYP_LOC586040.1.1,,,,,,,,, comp143382_c0_seq4,3568,42.0404,0.5309908,0,0,,,,,,,,,0,CHOYP_LOC586040.1.1,,,1.00E-107,AM866114.p.cg.6,5,,,, comp143382_c0_seq5,3520,42.1023,0.53676052,0,0,,0,Q8K2G4,Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1),Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1),GO:0034464; GO:0007420; GO:0005813; GO:0035085; GO:0036064; GO:0060170; GO:0001654; GO:0045444; GO:0007507; GO:0060173; GO:0005634; GO:0060021; GO:0008104; GO:0007224,BBSome; brain development; centrosome; cilium axoneme; cilium basal body; cilium membrane; eye development; fat cell differentiation; heart development; limb development; nucleus; palate development; protein localization; smoothened signaling pathway,,,,,,,,,,BBS7_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cilium assembly [GO:0042384]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; nonmotile primary cilium assembly [GO:0035058]; palate development [GO:0060021]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224] comp143382_c0_seq6,1040,37.5962,0.7185416,0,0,,4.00E-36,Q8K2G4,Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1),Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1),GO:0034464; GO:0007420; GO:0005813; GO:0035085; GO:0036064; GO:0060170; GO:0001654; GO:0045444; GO:0007507; GO:0060173; GO:0005634; GO:0060021; GO:0008104; GO:0007224,BBSome; brain development; centrosome; cilium axoneme; cilium basal body; cilium membrane; eye development; fat cell differentiation; heart development; limb development; nucleus; palate development; protein localization; smoothened signaling pathway,,,,,,,,,,BBS7_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cilium assembly [GO:0042384]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; nonmotile primary cilium assembly [GO:0035058]; palate development [GO:0060021]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224] comp143383_c0_seq1,1033,50.8228,0.5302103,136,121,,,,,,,,,,,2.00E-24,ruditapes_c17920,,,,,,, comp143383_c0_seq2,2288,42.0017,0.41066748,291,326,,9.00E-52,Q8BZH4,Pogo transposable element with ZNF domain,Pogo transposable element with ZNF domain,GO:0003677; GO:0051301; GO:0005737; GO:0051382; GO:0046872; GO:0007064; GO:0000790,DNA binding; cell division; cytoplasm; kinetochore assembly; metal ion binding; mitotic sister chromatid cohesion; nuclear chromatin,PF03184;PF03221;,5.00E-88,CHOYP_LOC100366436.1.1,,,,,,,POGZ_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; kinetochore assembly [GO:0051382]; mitotic sister chromatid cohesion [GO:0007064] comp143384_c0_seq1,2040,37.5,0.50585899,82,443,,6.00E-47,P34714,SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine),SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine),GO:0005604; GO:0005509; GO:0005615; GO:0007275; GO:0007165,basement membrane; calcium ion binding; extracellular space; multicellular organismal development; signal transduction,PF09289;PF07648;PF10591;,,,,,,,,,SPRC_CAEEL,Caenorhabditis elegans,multicellular organism development [GO:0007275]; signal transduction [GO:0007165] comp143384_c0_seq2,2121,37.9066,0.55595491,108,422,,6.00E-22,Q5R767,SPARC (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine),SPARC (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine),GO:0005604; GO:0005509; GO:0005615; GO:0007165,basement membrane; calcium ion binding; extracellular space; signal transduction,PF09289;PF00050;PF10591;,2.00E-22,CHOYP_LOC100374633.1.2,,,,,,,SPRC_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),signal transduction [GO:0007165] comp143386_c0_seq1,3046,37.9842,0.47800409,740,2222,,0,Q6AZV7,ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55),ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF13959;PF00271;,2.00E-56,CHOYP_DDX55.1.2,,,,,,,DDX55_XENLA,Xenopus laevis (African clawed frog), comp143389_c0_seq1,1473,42.1589,0.93413304,138,659,,1.00E-36,Q95NI4,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,5.00E-28,CHOYP_TSP_11726.2.2,,,,,,,CALM_HALOK,Halichondria okadai (Marine sponge) (Reniera okadai), comp143390_c0_seq2,3907,36.217,0.4476734,38,110,,8.00E-76,Q55FP0,Putative phagocytic receptor 1a,Putative phagocytic receptor 1a,GO:0008283; GO:0031589; GO:0042742; GO:0010467; GO:0005887; GO:0007042; GO:0006909; GO:0034394; GO:0061462; GO:0072657; GO:0050821; GO:0033299; GO:0030587; GO:0004888,cell proliferation; cell-substrate adhesion; defense response to bacterium; gene expression; integral to plasma membrane; lysosomal lumen acidification; phagocytosis; protein localization to cell surface; protein localization to lysosome; protein localization to membrane; protein stabilization; secretion of lysosomal enzymes; sorocarp development; transmembrane signaling receptor activity,PF02990;,0,CHOYP_BRAFLDRAFT_286243.1.1,,,,,,,PHG1A_DICDI,Dictyostelium discoideum (Slime mold),asexual reproduction [GO:0019954]; cell-substrate adhesion [GO:0031589]; defense response to bacterium [GO:0042742]; gene expression [GO:0010467]; lysosomal lumen acidification [GO:0007042]; phagocytosis [GO:0006909]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; protein localization to membrane [GO:0072657]; protein stabilization [GO:0050821]; secretion of lysosomal enzymes [GO:0033299]; sorocarp development [GO:0030587] comp143390_c0_seq8,3890,36.3496,0.44640962,11,92,,0,Q9HD45,Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein),Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein),GO:0016021,integral to membrane,PF02990;,0,CHOYP_BRAFLDRAFT_286243.1.1,,,,,,,TM9S3_HUMAN,Homo sapiens (Human), comp143393_c1_seq1,4440,37.8829,0.44897655,80,78,,1.00E-107,Q667Y5,Chaperone protein HscA (Hsc66),Chaperone protein HscA (Hsc66),GO:0005524; GO:0016887; GO:0016226; GO:0006457,ATP binding; ATPase activity; iron-sulfur cluster assembly; protein folding,PF00012;,0,CHOYP_GRP75.1.1,,,,,,,HSCA_YERPS,Yersinia pseudotuberculosis serotype I (strain IP32953),iron-sulfur cluster assembly [GO:0016226]; protein folding [GO:0006457] comp143393_c1_seq2,4408,37.7949,0.454209,10,135,,0,Q3ZCH0,"Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9)","Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9)",GO:0005524; GO:0009986; GO:0042645; GO:0005730; GO:0006611; GO:0006457,ATP binding; cell surface; mitochondrial nucleoid; nucleolus; protein export from nucleus; protein folding,PF00012;,0,CHOYP_GRP75.1.1,,,,,,,GRP75_BOVIN,Bos taurus (Bovine),erythrocyte differentiation [GO:0030218]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; negative regulation of hemopoiesis [GO:1903707]; protein export from nucleus [GO:0006611]; protein folding [GO:0006457] comp143397_c0_seq1,1880,42.9787,0.49563409,241,1890,,0,Q4R5Z4,Integrator complex subunit 9 (Int9),Integrator complex subunit 9 (Int9),GO:0016787; GO:0032039; GO:0016180,hydrolase activity; integrator complex; snRNA processing,PF10996;PF16661;,4.00E-157,CHOYP_INT9.1.1,3.00E-23,ruditapes_c15629,,,,,INT9_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),snRNA processing [GO:0016180] comp143398_c0_seq1,2280,41.2719,0.35441923,280,1357,,0,Q9Y2R4,Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52),Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52),GO:0005524; GO:0008026; GO:0003723; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus,PF00270;PF00271;,3.00E-135,CHOYP_LOC100372046.1.1,,,,,,,DDX52_HUMAN,Homo sapiens (Human),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp143402_c1_seq1,3115,42.1188,0.459286,509,2685,,0,P30876,DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2),DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2),GO:0006370; GO:0003677; GO:0005665; GO:0003899; GO:0003682; GO:0000398; GO:0046872; GO:0050434; GO:0032549; GO:0006368; GO:0006367; GO:0006283; GO:0016032,"7-methylguanosine mRNA capping; DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; chromatin binding; mRNA splicing, via spliceosome; metal ion binding; positive regulation of viral transcription; ribonucleoside binding; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; viral process",PF04563;PF04561;PF04565;PF04566;PF04567;PF00562;PF04560;,0,CHOYP_RPB2.1.1,4.00E-25,ruditapes_c31431,,,,,RPB2_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral transcription [GO:0050434]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp143404_c1_seq1,639,42.2535,0.67019564,45,238,,4.00E-49,P0C6P7,Protein fem-1 homolog B (FEM1b) (FEM1-beta),Protein fem-1 homolog B (FEM1b) (FEM1-beta),GO:0006915; GO:0060442; GO:0005737; GO:0060743; GO:0005634; GO:2000001; GO:1902041; GO:0051438; GO:0004842,apoptotic process; branching involved in prostate gland morphogenesis; cytoplasm; epithelial cell maturation involved in prostate gland development; nucleus; regulation of DNA damage checkpoint; regulation of extrinsic apoptotic signaling pathway via death domain receptors; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,PF00023;PF12796;,,,,,,,,,FEM1B_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; branching involved in prostate gland morphogenesis [GO:0060442]; epithelial cell maturation involved in prostate gland development [GO:0060743]; regulation of DNA damage checkpoint [GO:2000001]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of ubiquitin-protein transferase activity [GO:0051438] comp143404_c1_seq2,1309,41.1765,0.34604069,180,851,,4.00E-154,Q2T9K6,Protein fem-1 homolog C (FEM1c) (FEM1-gamma),Protein fem-1 homolog C (FEM1c) (FEM1-gamma),GO:0005737; GO:0016567,cytoplasm; protein ubiquitination,PF12796;,2.00E-160,CHOYP_FEM1C.1.1,,,,,,,FEM1C_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567] comp143406_c0_seq1,2119,34.7334,0.32929245,1054,2024,,9.00E-117,Q3ZCD7,"Very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER)","Very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER)",GO:0030497; GO:0030176; GO:0016627; GO:0006694; GO:0042761,"fatty acid elongation; integral to endoplasmic reticulum membrane; oxidoreductase activity, acting on the CH-CH group of donors; steroid biosynthetic process; very long-chain fatty acid biosynthetic process",PF02544;,2.00E-61,CHOYP_LOC100372208.1.1,,,,,,,TECR_BOVIN,Bos taurus (Bovine),fatty acid elongation [GO:0030497]; steroid biosynthetic process [GO:0006694]; very long-chain fatty acid biosynthetic process [GO:0042761] comp143411_c0_seq1,13724,43.9741,0.36686448,0,0,,0,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp143411_c0_seq2,9339,42.103,0.40441053,0,0,,1.00E-136,Q6ZR08,"Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)","Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;,0,CHOYP_DYHC.1.3,,,,,,,DYH12_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp143411_c0_seq3,12177,43.9763,0.36361967,0,0,,0,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp143411_c0_seq4,9352,42.0552,0.40238342,37,0,,1.00E-162,Q923J6,"Dynein heavy chain 12, axonemal (Bm259)","Dynein heavy chain 12, axonemal (Bm259)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;,0,CHOYP_DYHC.1.3,,,,,,,DYH12_RAT,Rattus norvegicus (Rat),microtubule-based movement [GO:0007018] comp143411_c0_seq5,6053,42.8548,0.39976589,0,0,,0,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp143411_c0_seq6,4506,42.4767,0.40232869,0,0,,0,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp143412_c0_seq1,4151,40.2072,0.38039232,32,76,,2.00E-157,Q9NVI1,Fanconi anemia group I protein (Protein FACI),Fanconi anemia group I protein (Protein FACI),GO:0003677; GO:0006281; GO:0007049; GO:0005654; GO:0005886; GO:0031398,DNA binding; DNA repair; cell cycle; nucleoplasm; plasma membrane; positive regulation of protein ubiquitination,PF14679;PF14680;PF14675;PF14674;PF14676;PF14677;PF14678;,2.00E-121,CHOYP_FANCI.1.1,,,,,,,FANCI_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; mitotic G2 DNA damage checkpoint [GO:0007095]; positive regulation of protein ubiquitination [GO:0031398] comp143412_c0_seq2,4164,40.1537,0.38607714,40,103,,2.00E-157,Q9NVI1,Fanconi anemia group I protein (Protein FACI),Fanconi anemia group I protein (Protein FACI),GO:0003677; GO:0006281; GO:0007049; GO:0005654; GO:0005886; GO:0031398,DNA binding; DNA repair; cell cycle; nucleoplasm; plasma membrane; positive regulation of protein ubiquitination,PF14679;PF14680;PF14675;PF14674;PF14676;PF14677;PF14678;,2.00E-121,CHOYP_FANCI.1.1,,,,,,,FANCI_HUMAN,Homo sapiens (Human),interstrand cross-link repair [GO:0036297]; mitotic G2 DNA damage checkpoint [GO:0007095]; positive regulation of protein ubiquitination [GO:0031398] comp143413_c1_seq1,740,37.8378,0.31010728,1,44,,1.00E-13,Q8VE99,Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1),Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1),GO:0005768; GO:0005764,endosome; lysosome,,,,,,,,,,CC115_MOUSE,Mus musculus (Mouse), comp143413_c1_seq5,739,38.1597,0.30665687,0,7,,2.00E-13,Q8VE99,Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1),Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1),GO:0005768; GO:0005764,endosome; lysosome,,,,,,,,,,CC115_MOUSE,Mus musculus (Mouse), comp143416_c2_seq1,2821,41.9355,0.42753914,195,1377,,0,Q8CI04,Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3),Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3),GO:0006888; GO:0032580; GO:0017119; GO:0005801; GO:0006891; GO:0006886; GO:0008565,ER to Golgi vesicle-mediated transport; Golgi cisterna membrane; Golgi transport complex; cis-Golgi network; intra-Golgi vesicle-mediated transport; intracellular protein transport; protein transporter activity,PF04136;,5.00E-158,CHOYP_COG3.1.1,,,,,,,COG3_MOUSE,Mus musculus (Mouse),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein glycosylation [GO:0006486]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp143417_c0_seq5,1208,39.3212,0.38609777,0,0,,5.00E-44,Q9CQM0,Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5) (p24),Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5) (p24),GO:0005874; GO:0005634,microtubule; nucleus,,,,3.00E-46,ruditapes_c14355,,,,,NICN1_MOUSE,Mus musculus (Mouse), comp143417_c0_seq6,1234,38.9789,0.38437623,0,0,,5.00E-42,Q861Y6,Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5),Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5),GO:0005874; GO:0005634,microtubule; nucleus,,,,,,,,,,NICN1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp143417_c0_seq8,745,44.8322,0.40124857,0,0,,,,,,,,,1.00E-19,CHOYP_LOC100378696.1.1,,,,,,,,, comp143420_c0_seq1,2272,33.0546,0.53855609,0,0,,2.00E-48,P56520,Histone deacetylase 3 (HD3) (EC 3.5.1.98),Histone deacetylase 3 (HD3) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0006355; GO:0008134; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF00850;,2.00E-54,CHOYP_LOC100368863.2.2,,,,,,,HDAC3_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp143420_c0_seq2,3216,35.541,0.57691552,76,360,,0,P56520,Histone deacetylase 3 (HD3) (EC 3.5.1.98),Histone deacetylase 3 (HD3) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0006355; GO:0008134; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF00850;,0,CHOYP_LOC100368863.2.2,,,,,,,HDAC3_CHICK,Gallus gallus (Chicken),"chromatin modification [GO:0016568]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp143421_c1_seq5,3342,37.0736,0.50247615,111,296,,0,Q8TCJ2,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog),GO:0030433; GO:0043686; GO:0004579; GO:0006516; GO:0016021; GO:0008250; GO:0043687; GO:0018279; GO:0006986,ER-associated protein catabolic process; co-translational protein modification; dolichyl-diphosphooligosaccharide-protein glycotransferase activity; glycoprotein catabolic process; integral to membrane; oligosaccharyltransferase complex; post-translational protein modification; protein N-linked glycosylation via asparagine; response to unfolded protein,PF02516;,0,CHOYP_STT3B.1.1,,,,,,,STT3B_HUMAN,Homo sapiens (Human),co-translational protein modification [GO:0043686]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986] comp143424_c0_seq1,1438,39.7775,0.45202128,140,595,,8.00E-81,Q5EA28,CpG-binding protein (CXXC-type zinc finger protein 1) (PHD finger and CXXC domain-containing protein 1),CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1),GO:0003677; GO:0048188; GO:0016363; GO:0016607; GO:0006355; GO:0006351; GO:0008270,"DNA binding; Set1C/COMPASS complex; nuclear matrix; nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF12269;PF02008;,2.00E-72,CHOYP_LOC590665.1.1,,,,,,,CXXC1_BOVIN,Bos taurus (Bovine),"positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp143426_c0_seq2,3876,30.7276,0.52664708,96,165,,2.00E-111,Q6RUV5,Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),GO:0005525; GO:0003924; GO:0000139; GO:0016601; GO:0060071; GO:0007015; GO:0048532; GO:0002093; GO:0007411; GO:0045453; GO:0008283; GO:0045216; GO:0021799; GO:0090103; GO:0031410; GO:0048813; GO:0071542; GO:0021831; GO:0043652; GO:0003382; GO:0019897; GO:0006972; GO:0030027; GO:0030032; GO:0002551; GO:0042470; GO:0001891; GO:0045740; GO:0030838; GO:0043552; GO:0001934; GO:0030334; GO:0097178; GO:0032587; GO:0034446,"GTP binding; GTPase activity; Golgi membrane; Rac protein signal transduction; Wnt receptor signaling pathway, planar cell polarity pathway; actin filament organization; anatomical structure arrangement; auditory receptor cell morphogenesis; axon guidance; bone resorption; cell proliferation; cell-cell junction organization; cerebral cortex radially oriented cell migration; cochlea morphogenesis; cytoplasmic vesicle; dendrite morphogenesis; dopaminergic neuron differentiation; embryonic olfactory bulb interneuron precursor migration; engulfment of apoptotic cell; epithelial cell morphogenesis; extrinsic to plasma membrane; hyperosmotic response; lamellipodium; lamellipodium assembly; mast cell chemotaxis; melanosome; phagocytic cup; positive regulation of DNA replication; positive regulation of actin filament polymerization; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of protein phosphorylation; regulation of cell migration; ruffle assembly; ruffle membrane; substrate adhesion-dependent cell spreading",PF00071;,8.00E-145,CHOYP_RAC1.3.3,6.00E-125,ruditapes2_c2197,,,,,RAC1_RAT,Rattus norvegicus (Rat),"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp143427_c1_seq1,318,44.3396,0.57790427,4,37,,2.00E-33,P49754,Vacuolar protein sorting-associated protein 41 homolog (S53),Vacuolar protein sorting-associated protein 41 homolog (S53),GO:0048193; GO:0005798; GO:0030897; GO:0005829; GO:0005769; GO:0006886; GO:0005770; GO:0005765; GO:0016020; GO:0005874; GO:0016192; GO:0008270,Golgi vesicle transport; Golgi-associated vesicle; HOPS complex; cytosol; early endosome; intracellular protein transport; late endosome; lysosomal membrane; membrane; microtubule; vesicle-mediated transport; zinc ion binding,PF00637;,,,,,,,,,VPS41_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; Golgi vesicle transport [GO:0048193]; late endosome to lysosome transport [GO:1902774]; protein targeting to vacuole [GO:0006623]; regulated exocytosis [GO:0045055]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]" comp143427_c2_seq1,1678,45.9476,0.47857499,90,159,,0,P49754,Vacuolar protein sorting-associated protein 41 homolog (S53),Vacuolar protein sorting-associated protein 41 homolog (S53),GO:0048193; GO:0005798; GO:0030897; GO:0005829; GO:0005769; GO:0006886; GO:0005770; GO:0005765; GO:0016020; GO:0005874; GO:0016192; GO:0008270,Golgi vesicle transport; Golgi-associated vesicle; HOPS complex; cytosol; early endosome; intracellular protein transport; late endosome; lysosomal membrane; membrane; microtubule; vesicle-mediated transport; zinc ion binding,PF00637;,4.00E-68,CHOYP_LOC100370879.1.1,,,,,,,VPS41_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; Golgi vesicle transport [GO:0048193]; late endosome to lysosome transport [GO:1902774]; protein targeting to vacuole [GO:0006623]; regulated exocytosis [GO:0045055]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]" comp143428_c0_seq3,281,42.7046,0.56741161,10,11,,7.00E-23,Q6GQN7,Rab9 effector protein with kelch motifs,Rab9 effector protein with kelch motifs,,,PF07646;,1.00E-14,CHOYP_LOC100373945.1.1,,,,,,,RABEK_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143428_c1_seq1,2798,40.7076,0.48337725,482,3003,,2.00E-120,P27641,X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku autoantigen protein p86 homolog) (Ku80) (Nuclear factor IV),X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku autoantigen protein p86 homolog) (Ku80) (Nuclear factor IV),GO:0051575; GO:0005524; GO:0004003; GO:0006310; GO:0043564; GO:0008283; GO:0005737; GO:0003684; GO:0006303; GO:0003691; GO:0060218; GO:0045892; GO:0070419; GO:0000784; GO:0005730; GO:0050769; GO:0000723; GO:0044212; GO:0006351,"5'-deoxyribose-5-phosphate lyase activity; ATP binding; ATP-dependent DNA helicase activity; DNA recombination; Ku70:Ku80 complex; cell proliferation; cytoplasm; damaged DNA binding; double-strand break repair via nonhomologous end joining; double-stranded telomeric DNA binding; hematopoietic stem cell differentiation; negative regulation of transcription, DNA-dependent; nonhomologous end joining complex; nuclear chromosome, telomeric region; nucleolus; positive regulation of neurogenesis; telomere maintenance; transcription regulatory region DNA binding; transcription, DNA-dependent",PF02735;PF03730;PF03731;PF08785;,0,CHOYP_LOC583472.1.1,,,,,,,XRCC5_MOUSE,Mus musculus (Mouse),"cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to X-ray [GO:0071481]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; hematopoietic stem cell differentiation [GO:0060218]; negative regulation of t-circle formation [GO:1904430]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neurogenesis [GO:0050769]; regulation of smooth muscle cell proliferation [GO:0048660]; telomere maintenance [GO:0000723]; transcription, DNA-templated [GO:0006351]" comp143429_c0_seq1,3379,36.4309,0.37602639,1084,7290,,0,Q5RA77,Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP),Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP),GO:0030126; GO:0030131; GO:0006886; GO:0006890,"COPI vesicle coat; clathrin adaptor complex; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER",PF00928;PF01217;,0,CHOYP_COPD.1.1,,,,,,,COPD_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp143430_c0_seq10,2896,40.9185,0.52877634,0,0,,3.00E-169,A0JM56,Leucine-rich repeat-containing protein 9,Leucine-rich repeat-containing protein 9,,,PF13855;,,,,,,,,,LRRC9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143430_c0_seq11,2911,41.1199,0.54537939,0,0,,1.00E-10,Q1RMR5,Protein tilB homolog (Leucine-rich repeat-containing protein 6) (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein),Protein tilB homolog (Leucine-rich repeat-containing protein 6) (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein),GO:0005929; GO:0005737; GO:0060287; GO:0036159; GO:0008584; GO:0044458; GO:0036158; GO:0030317,cilium; cytoplasm; epithelial cilium movement involved in determination of left/right asymmetry; inner dynein arm assembly; male gonad development; motile cilium assembly; outer dynein arm assembly; sperm motility,,7.00E-144,CHOYP_LOC578913.1.1,,,,,,,TILB_BOVIN,Bos taurus (Bovine),cilium movement [GO:0003341]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inner dynein arm assembly [GO:0036159]; male gonad development [GO:0008584]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp143430_c0_seq12,941,35.813,0.29866869,0,0,,7.00E-81,Q8CDN9,Leucine-rich repeat-containing protein 9,Leucine-rich repeat-containing protein 9,,,PF13855;,8.00E-49,CHOYP_LOC100372309.1.1,,,,,,,LRRC9_MOUSE,Mus musculus (Mouse), comp143430_c0_seq2,1844,39.2082,0.4284057,194,0,,1.00E-17,Q3T0W4,Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),GO:0005634,nucleus,,,,,,,,,,PP1R7_BOVIN,Bos taurus (Bovine),chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307] comp143430_c0_seq4,2932,41.0982,0.54223998,0,0,,6.00E-163,A0JM56,Leucine-rich repeat-containing protein 9,Leucine-rich repeat-containing protein 9,,,PF13855;,,,,,,,,,LRRC9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143430_c0_seq6,2875,40.9391,0.53193697,0,0,,3.00E-162,Q6ZRR7,Leucine-rich repeat-containing protein 9,Leucine-rich repeat-containing protein 9,,,,7.00E-144,CHOYP_LOC578913.1.1,,,,,,,LRRC9_HUMAN,Homo sapiens (Human), comp143431_c0_seq1,2539,42.1032,0.44854143,32,87,,0,Q6AZN6,Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3),Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3),GO:0016303; GO:0005524; GO:0006914; GO:0000910; GO:0030496; GO:0048015,1-phosphatidylinositol-3-kinase activity; ATP binding; autophagy; cytokinesis; midbody; phosphatidylinositol-mediated signaling,PF00454;PF00792;PF00613;,,,,,,,,,PK3C3_XENLA,Xenopus laevis (African clawed frog),autophagy [GO:0006914]; cytokinesis [GO:0000910]; phosphatidylinositol-mediated signaling [GO:0048015] comp143431_c0_seq2,1767,40.2377,0.40955361,0,0,,1.00E-110,P50520,Phosphatidylinositol 3-kinase vps34 (PI3-kinase vps34) (PI3K vps34) (PtdIns-3-kinase vps34) (EC 2.7.1.137) (Vacuolar protein sorting-associated protein 34),Phosphatidylinositol 3-kinase vps34 (PI3-kinase vps34) (PI3K vps34) (PtdIns-3-kinase vps34) (EC 2.7.1.137) (Vacuolar protein sorting-associated protein 34),GO:0016303; GO:0005524; GO:0030476; GO:0031321; GO:0016020; GO:0005942; GO:0048015; GO:0075296; GO:2001232; GO:1900485; GO:0006623; GO:0007033; GO:0016192,1-phosphatidylinositol-3-kinase activity; ATP binding; ascospore wall assembly; ascospore-type prospore assembly; membrane; phosphatidylinositol 3-kinase complex; phosphatidylinositol-mediated signaling; positive regulation of ascospore formation; positive regulation of protein targeting to prospore membrane; positive regulation of protein targeting to vacuolar membrane; protein targeting to vacuole; vacuole organization; vesicle-mediated transport,PF00454;PF00792;PF00613;,7.00E-123,CHOYP_PK3C3.1.1,2.00E-38,ruditapes_c10968,,,,,VPS34_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ascospore-type prospore membrane assembly [GO:0032120]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of ascospore formation [GO:0075296]; protein localization to prospore membrane [GO:1902657]; protein localization to vacuole [GO:0072665] comp143433_c1_seq1,3104,44.1366,0.70074332,0,0,,2.00E-19,Q9VAW5,La-related protein (dlarp),La-related protein 1 (dLarp),GO:0003723; GO:0005829; GO:0000001; GO:0035071; GO:0007053; GO:0035186,RNA binding; cytosol; mitochondrion inheritance; salivary gland cell autophagic cell death; spindle assembly involved in male meiosis; syncytial blastoderm mitotic cell cycle,PF05383;,,,,,,,,,LARP_DROME,Drosophila melanogaster (Fruit fly),autophagic cell death [GO:0048102]; centrosome separation [GO:0051299]; male meiosis [GO:0007140]; mitochondrion inheritance [GO:0000001]; mitotic chromosome condensation [GO:0007076]; salivary gland cell autophagic cell death [GO:0035071]; spindle assembly [GO:0051225]; spindle assembly involved in male meiosis [GO:0007053]; syncytial blastoderm mitotic cell cycle [GO:0035186] comp143433_c1_seq2,3184,44.0327,0.69971981,12,14,,2.00E-38,Q6ZQ58,La-related protein 1 (La ribonucleoprotein domain family member 1),La-related protein 1 (La ribonucleoprotein domain family member 1),GO:0003723; GO:0005737,RNA binding; cytoplasm,PF05383;,,,,,,,,,LARP1_MOUSE,Mus musculus (Mouse),cell proliferation [GO:0008283]; positive regulation of macroautophagy [GO:0016239]; positive regulation of viral genome replication [GO:0045070]; TOR signaling [GO:0031929]; translational initiation [GO:0006413] comp143433_c1_seq4,667,49.4753,0.63831964,1,0,,,,,,,,,4.00E-44,CHOYP_LOC100552337.1.1,,,,,,,,, comp143433_c1_seq5,3139,43.963,0.69909318,1,1,,9.00E-11,Q9P6K0,Uncharacterized HTH La-type RNA-binding protein C1527.03,Uncharacterized HTH La-type RNA-binding protein C1527.03,GO:0003723; GO:0002181; GO:0005829; GO:0005844,RNA binding; cytoplasmic translation; cytosol; polysome,PF05383;,,,,,,,,,YLA3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translation [GO:0002181] comp143433_c1_seq6,873,40.3207,0.56843754,3,0,,,,,,,,,,,2.00E-41,ruditapes_c31996,,,,,,, comp143433_c1_seq7,3149,44.268,0.69969055,0,0,,9.00E-11,P40796,La protein homolog (La autoantigen homolog) (La ribonucleoprotein),La protein homolog (La autoantigen homolog) (La ribonucleoprotein),GO:0008098; GO:0003677; GO:0006396; GO:0003729; GO:0000166; GO:0005634; GO:0030529,5S rRNA primary transcript binding; DNA binding; RNA processing; mRNA binding; nucleotide binding; nucleus; ribonucleoprotein complex,PF05383;PF08777;,,,,,,,,,LA_DROME,Drosophila melanogaster (Fruit fly),RNA processing [GO:0006396] comp143433_c1_seq8,1272,37.8145,0.42093656,29,25,,3.00E-59,Q6ZQ58,La-related protein 1 (La ribonucleoprotein domain family member 1),La-related protein 1 (La ribonucleoprotein domain family member 1),GO:0003723; GO:0005737,RNA binding; cytoplasm,PF05383;,1.00E-74,CHOYP_LOC100552337.1.1,,,,,,,LARP1_MOUSE,Mus musculus (Mouse),cell proliferation [GO:0008283]; positive regulation of macroautophagy [GO:0016239]; positive regulation of viral genome replication [GO:0045070]; TOR signaling [GO:0031929]; translational initiation [GO:0006413] comp143436_c2_seq2,2067,44.1219,0.66071277,22,0,,4.00E-107,B6ZLK2,Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1),GO:0005524; GO:0003677; GO:0000775; GO:0004386; GO:0005634; GO:0006355; GO:0006351,"ATP binding; DNA binding; chromosome, centromeric region; helicase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00385;PF13907;PF00271;PF00176;,3.00E-71,CHOYP_CHD2.1.1,,,,,,,CHD1_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143436_c2_seq4,2142,44.4444,0.64811895,1,0,,,,,,,,,3.00E-71,CHOYP_CHD2.1.1,,,,,,,,, comp143437_c1_seq1,4153,38.0929,0.4312589,103,276,,2.00E-65,P40352,DNA repair and recombination protein RAD26 (EC 3.6.4.12) (ATP-dependent helicase RAD26),DNA repair and recombination protein RAD26 (EC 3.6.4.12) (ATP-dependent helicase RAD26),GO:0005524; GO:0003677; GO:0008094; GO:0004386; GO:0005634; GO:0006283,ATP binding; DNA binding; DNA-dependent ATPase activity; helicase activity; nucleus; transcription-coupled nucleotide-excision repair,PF00271;PF00176;,6.00E-14,CHOYP_SMARCA5.1.1,,,,,,,RAD26_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),histone H2A-H2B dimer displacement [GO:0001208]; nucleotide-excision repair [GO:0006289]; transcription-coupled nucleotide-excision repair [GO:0006283] comp143437_c1_seq2,6720,41.994,0.3519571,103,288,,0,A7Z019,Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),GO:0005524; GO:0003677; GO:0008094; GO:0001105; GO:0016514; GO:0071778; GO:0006338; GO:0004386; GO:0071565; GO:0060766; GO:0030308; GO:0045892; GO:0007399; GO:0003407; GO:0071564; GO:0000790; GO:0006337; GO:0043923; GO:0051091; GO:0003714,"ATP binding; DNA binding; DNA-dependent ATPase activity; RNA polymerase II transcription coactivator activity; SWI/SNF complex; WINAC complex; chromatin remodeling; helicase activity; nBAF complex; negative regulation of androgen receptor signaling pathway; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; nervous system development; neural retina development; npBAF complex; nuclear chromatin; nucleosome disassembly; positive regulation by host of viral transcription; positive regulation of sequence-specific DNA binding transcription factor activity; transcription corepressor activity",PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;,0,CHOYP_SMCA4.1.1,,,,,,,SMCA4_BOVIN,Bos taurus (Bovine),"ATP-dependent chromatin remodeling [GO:0043044]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143437_c1_seq3,2663,47.8783,0.25804725,3,25,,6.00E-112,P51531,Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2),Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2),GO:0005524; GO:0008094; GO:0001105; GO:0016514; GO:0071778; GO:0035887; GO:0006338; GO:0004386; GO:0045111; GO:0071565; GO:0030308; GO:0008285; GO:0000122; GO:0007399; GO:0071564; GO:0000790; GO:0005654; GO:0044212,ATP binding; DNA-dependent ATPase activity; RNA polymerase II transcription coactivator activity; SWI/SNF complex; WINAC complex; aortic smooth muscle cell differentiation; chromatin remodeling; helicase activity; intermediate filament cytoskeleton; nBAF complex; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nervous system development; npBAF complex; nuclear chromatin; nucleoplasm; transcription regulatory region DNA binding,PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;,4.00E-83,CHOYP_SMCA4.1.1,,,,,,,SMCA2_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatid development [GO:0007286]" comp143438_c0_seq4,1510,43.4437,0.40046209,30,50,,3.00E-06,O94927,HAUS augmin-like complex subunit 5,HAUS augmin-like complex subunit 5,GO:0070652; GO:0051301; GO:0005813; GO:0051297; GO:0005737; GO:0005874; GO:0007067; GO:0005819; GO:0051225,HAUS complex; cell division; centrosome; centrosome organization; cytoplasm; microtubule; mitosis; spindle; spindle assembly,PF14817;,,,,,,,,,HAUS5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225] comp143439_c0_seq10,2465,38.2961,0.49562519,0,0,,2.00E-53,Q0VCA3,"LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)","LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)",GO:0005509; GO:0016021; GO:0005743,calcium ion binding; integral to membrane; mitochondrial inner membrane,PF07766;,,,,,,,,,LETM1_BOVIN,Bos taurus (Bovine), comp143439_c0_seq13,2243,38.1632,0.48962165,0,0,,,,,,,,,,,2.00E-28,ruditapes_c17186,,,,,,, comp143439_c0_seq14,2460,38.5366,0.55686091,0,0,,4.00E-52,Q0VCA3,"LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)","LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)",GO:0005509; GO:0016021; GO:0005743,calcium ion binding; integral to membrane; mitochondrial inner membrane,PF07766;,,,,,,,,,LETM1_BOVIN,Bos taurus (Bovine), comp143439_c0_seq2,2444,38.2979,0.51092334,2,0,,2.00E-53,Q0VCA3,"LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)","LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)",GO:0005509; GO:0016021; GO:0005743,calcium ion binding; integral to membrane; mitochondrial inner membrane,PF07766;,,,,,,,,,LETM1_BOVIN,Bos taurus (Bovine), comp143439_c0_seq3,2441,38.263,0.50092316,0,0,,4.00E-36,Q5PQQ5,"LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)","LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)",GO:0016021; GO:0005743,integral to membrane; mitochondrial inner membrane,PF07766;,,,,,,,,,LETM2_RAT,Rattus norvegicus (Rat), comp143439_c0_seq4,2420,38.2645,0.50513867,0,0,,5.00E-35,Q28DA8,"LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)","LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)",GO:0016021; GO:0005743,integral to membrane; mitochondrial inner membrane,PF07766;,,,,,,,,,LETM2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143439_c0_seq8,2481,38.5732,0.56283793,0,0,,4.00E-52,Q0VCA3,"LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)","LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)",GO:0005509; GO:0016021; GO:0005743,calcium ion binding; integral to membrane; mitochondrial inner membrane,PF07766;,,,,,,,,,LETM1_BOVIN,Bos taurus (Bovine), comp143440_c0_seq3,554,37.9061,0.20402603,33,67,,9.00E-10,Q9VLT5,Protein purity of essence (Interaction calmodulin and colossal molecular mass protein) (Protein Calossin) (Protein pushover),Protein purity of essence (Interaction calmodulin and colossal molecular mass protein) (Protein Calossin) (Protein pushover),GO:0005516; GO:0042066; GO:0016567; GO:0050896; GO:0007291; GO:0004842; GO:0007601; GO:0008270,calmodulin binding; perineurial glial growth; protein ubiquitination; response to stimulus; sperm individualization; ubiquitin-protein ligase activity; visual perception; zinc ion binding,PF13764;PF02207;,3.00E-19,CHOYP_UBR4.1.1,,,,,,,POE_DROME,Drosophila melanogaster (Fruit fly),glial cell growth [GO:0042065]; perineurial glial growth [GO:0042066]; response to stimulus [GO:0050896]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]; visual perception [GO:0007601] comp143440_c0_seq9,267,41.1985,0.17719257,5,13,,,,,,,,,,,4.00E-12,ruditapes_c20886,,,,,,, comp143443_c0_seq1,2136,39.4663,0.5073543,11,10,,4.00E-134,Q91628,Origin recognition complex subunit 2 (xORC2),Origin recognition complex subunit 2 (xORC2),GO:0006260; GO:0005634; GO:0000808,DNA replication; nucleus; origin recognition complex,PF04084;,,,,,,,,,ORC2_XENLA,Xenopus laevis (African clawed frog),DNA replication [GO:0006260] comp143443_c0_seq2,2129,39.9248,0.48544725,2,84,,4.00E-134,Q91628,Origin recognition complex subunit 2 (xORC2),Origin recognition complex subunit 2 (xORC2),GO:0006260; GO:0005634; GO:0000808,DNA replication; nucleus; origin recognition complex,PF04084;,2.00E-85,CHOYP_LOC100371654.1.1,,,,,,,ORC2_XENLA,Xenopus laevis (African clawed frog),DNA replication [GO:0006260] comp143445_c0_seq1,3059,30.2386,0.54188848,0,0,,6.00E-49,Q5R6X7,Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),GO:0016568; GO:0000779; GO:0045892; GO:0031618; GO:0005635; GO:0005719; GO:0019904; GO:0005819; GO:0006351,"chromatin modification; condensed chromosome, centromeric region; negative regulation of transcription, DNA-dependent; nuclear centromeric heterochromatin; nuclear envelope; nuclear euchromatin; protein domain specific binding; spindle; transcription, DNA-dependent",PF00385;PF01393;,6.00E-114,CHOYP_CBX1.4.4,,,,,,,CBX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp143445_c0_seq12,1176,35.2041,0.56959004,0,0,,1.00E-51,Q5R6X7,Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),GO:0016568; GO:0000779; GO:0045892; GO:0031618; GO:0005635; GO:0005719; GO:0019904; GO:0005819; GO:0006351,"chromatin modification; condensed chromosome, centromeric region; negative regulation of transcription, DNA-dependent; nuclear centromeric heterochromatin; nuclear envelope; nuclear euchromatin; protein domain specific binding; spindle; transcription, DNA-dependent",PF00385;PF01393;,,,,,8.00E-111,AM863306.p.cg.6,9,,CBX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp143445_c0_seq2,1151,34.9262,0.56185067,0,0,,2.00E-08,Q5F3W5,Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2),Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2),GO:0007049; GO:0030154; GO:0000785; GO:0006333; GO:0006338; GO:0000775; GO:0051567; GO:0046974; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"cell cycle; cell differentiation; chromatin; chromatin assembly or disassembly; chromatin remodeling; chromosome, centromeric region; histone H3-K9 methylation; histone methyltransferase activity (H3-K9 specific); nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00385;PF05033;PF00856;,1.00E-117,CHOYP_CBX1.1.4,,,,,,,SUV92_CHICK,Gallus gallus (Chicken),"cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hypoxia [GO:0071456]; chromatin assembly or disassembly [GO:0006333]; chromatin remodeling [GO:0006338]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp143445_c0_seq3,3045,30.2463,0.5298723,0,0,,,,,,,,,3.00E-117,CHOYP_CBX1.4.4,,,,,,,,, comp143445_c0_seq5,2289,31.1053,0.5011673,0,0,,,,,,,,,4.00E-114,CHOYP_CBX1.1.4,,,,,,,,, comp143445_c0_seq6,3033,30.0692,0.52301075,103,262,,5.00E-49,Q5R6X7,Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),GO:0016568; GO:0000779; GO:0045892; GO:0031618; GO:0005635; GO:0005719; GO:0019904; GO:0005819; GO:0006351,"chromatin modification; condensed chromosome, centromeric region; negative regulation of transcription, DNA-dependent; nuclear centromeric heterochromatin; nuclear envelope; nuclear euchromatin; protein domain specific binding; spindle; transcription, DNA-dependent",PF00385;PF01393;,5.00E-114,CHOYP_CBX1.4.4,8.00E-72,ruditapes_c20332,,,,,CBX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp143445_c0_seq8,3043,30.2005,0.54666362,0,0,,5.00E-49,Q5R6X7,Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma),GO:0016568; GO:0000779; GO:0045892; GO:0031618; GO:0005635; GO:0005719; GO:0019904; GO:0005819; GO:0006351,"chromatin modification; condensed chromosome, centromeric region; negative regulation of transcription, DNA-dependent; nuclear centromeric heterochromatin; nuclear envelope; nuclear euchromatin; protein domain specific binding; spindle; transcription, DNA-dependent",PF00385;PF01393;,,,,,,,,,CBX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp143445_c0_seq9,3249,30.1016,0.57218315,0,0,,,,,,,,,3.00E-117,CHOYP_CBX1.4.4,,,,,,,,, comp143446_c0_seq1,2950,45.0508,0.36089361,37,310,,1.00E-51,O88572,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0090245; GO:0046849; GO:0060444; GO:0061310; GO:0061324; GO:0005901; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0060026; GO:0015026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0051593; GO:0048705; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; axis elongation involved in somitogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; caveola; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; convergent extension; coreceptor activity; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; response to folic acid; skeletal system morphogenesis; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,,,,,,,,,LRP6_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp143446_c0_seq3,2445,44.5808,0.30502767,8,86,,1.00E-20,P10493,Nidogen-1 (NID-1) (Entactin),Nidogen-1 (NID-1) (Entactin),GO:0005605; GO:0005509; GO:0071944; GO:0007160; GO:0005518; GO:0032836; GO:0043237; GO:0010811,basal lamina; calcium ion binding; cell periphery; cell-matrix adhesion; collagen binding; glomerular basement membrane development; laminin-1 binding; positive regulation of cell-substrate adhesion,PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID1_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; positive regulation of cell-substrate adhesion [GO:0010811] comp143447_c0_seq1,984,37.3984,0.23712823,244,1920,,7.00E-46,Q9NV35,"Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)","Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)",GO:0035539; GO:0008413; GO:0006184; GO:0005829; GO:0006203; GO:0046872; GO:0034656,"8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; GTP catabolic process; cytosol; dGTP catabolic process; metal ion binding; nucleobase-containing small molecule catabolic process",PF00293;,,,,,,,,,NUD15_HUMAN,Homo sapiens (Human),dGTP catabolic process [GO:0006203]; nucleobase-containing small molecule catabolic process [GO:0034656] comp143448_c0_seq2,1761,37.7626,0.54777554,140,565,,2.00E-39,Q9QY33,Tetraspanin-3 (Tspan-3) (OSP-associated protein 1) (OAP-1) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8),Tetraspanin-3 (Tspan-3) (OSP-associated protein 1) (OAP-1) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8),GO:0016021,integral to membrane,PF00335;,1.00E-12,CHOYP_TSN3.1.1,5.00E-59,ruditapes_c3718,,,,,TSN3_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166] comp143449_c0_seq1,3309,40.5561,0.39469928,2923,6617,,0,Q9ER34,"Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)","Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)",GO:0051538; GO:0051539; GO:0003994; GO:0006101; GO:0005506; GO:0006102; GO:0005739; GO:0005634; GO:0006099,"3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; citrate metabolic process; iron ion binding; isocitrate metabolic process; mitochondrion; nucleus; tricarboxylic acid cycle",PF00330;PF00694;,0,CHOYP_ACON.1.1,4.00E-82,ruditapes_c11009,,,,,ACON_RAT,Rattus norvegicus (Rat),citrate metabolic process [GO:0006101]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099] comp143450_c0_seq1,2312,48.5294,0.59849551,2,4,,0,Q00174,Laminin subunit alpha (Laminin A chain),Laminin subunit alpha (Laminin A chain),GO:0030424; GO:0007411; GO:0005605; GO:0048854; GO:0007155; GO:0030054; GO:0035001; GO:0016321; GO:0007507; GO:0007476; GO:0002121; GO:0005606; GO:0031987; GO:0035011; GO:0007498; GO:0045886; GO:0036062; GO:0030155; GO:0030334; GO:0045995; GO:0001964; GO:0008021,"axon; axon guidance; basal lamina; brain morphogenesis; cell adhesion; cell junction; dorsal trunk growth, open tracheal system; female meiosis chromosome segregation; heart development; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; laminin-1 complex; locomotion involved in locomotory behavior; melanotic encapsulation of foreign target; mesoderm development; negative regulation of synaptic growth at neuromuscular junction; presynaptic periactive zone; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; startle response; synaptic vesicle",PF00052;PF00053;PF00054;PF02210;PF06008;PF06009;PF00055;,,,,,,,,,LAMA_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; brain morphogenesis [GO:0048854]; cell adhesion mediated by integrin [GO:0033627]; central nervous system development [GO:0007417]; dorsal trunk growth, open tracheal system [GO:0035001]; embryonic morphogenesis [GO:0048598]; female meiosis chromosome segregation [GO:0016321]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; locomotion involved in locomotory behavior [GO:0031987]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; organ morphogenesis [GO:0009887]; peripheral nervous system development [GO:0007422]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of glucose metabolic process [GO:0010906]; startle response [GO:0001964]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]" comp143450_c0_seq10,1094,50.8227,0.62418028,0,0,,2.00E-59,P07942,Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta),Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta),GO:0007411; GO:0007566; GO:0030198; GO:0005201; GO:0005615; GO:0070062; GO:0043208; GO:0005606; GO:0043259; GO:0005607; GO:0043257; GO:0007162; GO:0021812; GO:0042476; GO:0048471; GO:0030335; GO:0050679; GO:0034446,axon guidance; embryo implantation; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; extracellular vesicular exosome; glycosphingolipid binding; laminin-1 complex; laminin-10 complex; laminin-2 complex; laminin-8 complex; negative regulation of cell adhesion; neuronal-glial interaction involved in cerebral cortex radial glia guided migration; odontogenesis; perinuclear region of cytoplasm; positive regulation of cell migration; positive regulation of epithelial cell proliferation; substrate adhesion-dependent cell spreading,PF00053;PF00055;,,,,,,,,,LAMB1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; neuron projection development [GO:0031175]; odontogenesis [GO:0042476]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; substrate adhesion-dependent cell spreading [GO:0034446] comp143450_c0_seq2,5212,47.429,0.5837657,6,21,,0,Q00174,Laminin subunit alpha (Laminin A chain),Laminin subunit alpha (Laminin A chain),GO:0030424; GO:0007411; GO:0005605; GO:0048854; GO:0007155; GO:0030054; GO:0035001; GO:0016321; GO:0007507; GO:0007476; GO:0002121; GO:0005606; GO:0031987; GO:0035011; GO:0007498; GO:0045886; GO:0036062; GO:0030155; GO:0030334; GO:0045995; GO:0001964; GO:0008021,"axon; axon guidance; basal lamina; brain morphogenesis; cell adhesion; cell junction; dorsal trunk growth, open tracheal system; female meiosis chromosome segregation; heart development; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; laminin-1 complex; locomotion involved in locomotory behavior; melanotic encapsulation of foreign target; mesoderm development; negative regulation of synaptic growth at neuromuscular junction; presynaptic periactive zone; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; startle response; synaptic vesicle",PF00052;PF00053;PF00054;PF02210;PF06008;PF06009;PF00055;,1.00E-149,CHOYP_LOC100875585.1.1,,,,,,,LAMA_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; brain morphogenesis [GO:0048854]; cell adhesion mediated by integrin [GO:0033627]; central nervous system development [GO:0007417]; dorsal trunk growth, open tracheal system [GO:0035001]; embryonic morphogenesis [GO:0048598]; female meiosis chromosome segregation [GO:0016321]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; locomotion involved in locomotory behavior [GO:0031987]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; organ morphogenesis [GO:0009887]; peripheral nervous system development [GO:0007422]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of glucose metabolic process [GO:0010906]; startle response [GO:0001964]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]" comp143450_c0_seq3,542,49.8155,0.68072487,0,0,,8.00E-29,Q16363,Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha),Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha),GO:0005605; GO:0001568; GO:0050873; GO:0007155; GO:0030198; GO:0005201; GO:0070062; GO:0005606; GO:0030155; GO:0030334; GO:0045995,basal lamina; blood vessel development; brown fat cell differentiation; cell adhesion; extracellular matrix organization; extracellular matrix structural constituent; extracellular vesicular exosome; laminin-1 complex; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development,PF00053;PF00054;PF02210;PF06008;PF06009;,,,,,,,,,LAMA4_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995] comp143450_c0_seq4,2272,46.4789,0.49906965,0,0,,4.00E-21,Q13753,Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma),Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma),GO:0007155; GO:0008544; GO:0030198; GO:0005576; GO:0031581; GO:0008201; GO:0005610,cell adhesion; epidermis development; extracellular matrix organization; extracellular region; hemidesmosome assembly; heparin binding; laminin-5 complex,PF00052;PF00053;,,,,,,,,,LAMC2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581] comp143450_c0_seq6,2667,48.2565,0.63131455,0,0,,0,Q00174,Laminin subunit alpha (Laminin A chain),Laminin subunit alpha (Laminin A chain),GO:0030424; GO:0007411; GO:0005605; GO:0048854; GO:0007155; GO:0030054; GO:0035001; GO:0016321; GO:0007507; GO:0007476; GO:0002121; GO:0005606; GO:0031987; GO:0035011; GO:0007498; GO:0045886; GO:0036062; GO:0030155; GO:0030334; GO:0045995; GO:0001964; GO:0008021,"axon; axon guidance; basal lamina; brain morphogenesis; cell adhesion; cell junction; dorsal trunk growth, open tracheal system; female meiosis chromosome segregation; heart development; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; laminin-1 complex; locomotion involved in locomotory behavior; melanotic encapsulation of foreign target; mesoderm development; negative regulation of synaptic growth at neuromuscular junction; presynaptic periactive zone; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; startle response; synaptic vesicle",PF00052;PF00053;PF00054;PF02210;PF06008;PF06009;PF00055;,1.00E-140,CHOYP_LOC100875585.1.1,,,,,,,LAMA_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; brain morphogenesis [GO:0048854]; cell adhesion mediated by integrin [GO:0033627]; central nervous system development [GO:0007417]; dorsal trunk growth, open tracheal system [GO:0035001]; embryonic morphogenesis [GO:0048598]; female meiosis chromosome segregation [GO:0016321]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; locomotion involved in locomotory behavior [GO:0031987]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; organ morphogenesis [GO:0009887]; peripheral nervous system development [GO:0007422]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of glucose metabolic process [GO:0010906]; startle response [GO:0001964]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]" comp143450_c0_seq7,1101,50.8629,0.63562529,0,0,,3.00E-60,P15215,Laminin subunit gamma-1 (Laminin B2 chain),Laminin subunit gamma-1 (Laminin B2 chain),GO:0005605; GO:0007155,basal lamina; cell adhesion,PF00052;PF00053;PF00055;,,,,,,,,,LAMC1_DROME,Drosophila melanogaster (Fruit fly),basement membrane assembly [GO:0070831]; cell adhesion mediated by integrin [GO:0033627]; embryonic morphogenesis [GO:0048598]; endodermal digestive tract morphogenesis [GO:0061031]; extracellular matrix assembly [GO:0085029]; midgut development [GO:0007494]; organ morphogenesis [GO:0009887]; salivary gland morphogenesis [GO:0007435]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] comp143451_c0_seq1,2674,45.101,0.45252985,589,427,,9.00E-34,Q3UHK8,Trinucleotide repeat-containing gene 6A protein,Trinucleotide repeat-containing gene 6A protein,GO:0003723; GO:0009267; GO:0000932; GO:0032507; GO:0035068; GO:0035278; GO:0000166; GO:0048471; GO:1900153; GO:0060213; GO:0032947,"RNA binding; cellular response to starvation; cytoplasmic mRNA processing body; maintenance of protein location in cell; micro-ribonucleoprotein complex; negative regulation of translation involved in gene silencing by miRNA; nucleotide binding; perinuclear region of cytoplasm; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; protein complex scaffold",PF10427;PF16608;,5.00E-25,CHOYP_TNRC6A.1.2,3.00E-45,ruditapes_c26089,,,,,TNR6A_MOUSE,Mus musculus (Mouse),"cellular response to starvation [GO:0009267]; gene silencing by miRNA [GO:0035195]; gene silencing by RNA [GO:0031047]; maintenance of protein location in cell [GO:0032507]; miRNA mediated inhibition of translation [GO:0035278]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]" comp143451_c2_seq1,1614,39.3432,0.92060559,38,699,,2.00E-98,Q9UBQ7,Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81),GO:0051287; GO:0070402; GO:0034641; GO:0007588; GO:0008465; GO:0046487; GO:0030267; GO:0016618; GO:0005782; GO:0042803; GO:0051259,NAD binding; NADPH binding; cellular nitrogen compound metabolic process; excretion; glycerate dehydrogenase activity; glyoxylate metabolic process; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity; peroxisomal matrix; protein homodimerization activity; protein oligomerization,PF00389;PF02826;,,,2.00E-70,ruditapes_c7712,,,,,GRHPR_HUMAN,Homo sapiens (Human),dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259] comp143452_c0_seq1,2073,41.1963,0.79755972,554,404,,1.00E-71,P62284,Abnormal spindle-like microcephaly-associated protein homolog (Fragment),Abnormal spindle-like microcephaly-associated protein homolog (Fragment),GO:0051301; GO:0005737; GO:0007067; GO:0005634,cell division; cytoplasm; mitosis; nucleus,PF00612;,,,,,,,,,ASPM_ATEGE,Ateles geoffroyi (Black-handed spider monkey) (Geoffroy's spider monkey),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp143454_c0_seq1,2830,40.3534,0.67439804,1731,1,male>female,8.00E-116,Q5THR3,EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP),EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP),GO:0005509; GO:0005634; GO:0006355; GO:0006351,"calcium ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08976;PF13833;,,,6.00E-54,ruditapes_c20815,,,,,EFCB6_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143454_c0_seq2,827,41.3543,0.77217576,3,0,,2.00E-06,P14533,Squidulin (Optic lobe calcium-binding protein) (SCABP),Squidulin (Optic lobe calcium-binding protein) (SCABP),GO:0005509,calcium ion binding,PF13499;,2.00E-42,CHOYP_LOC757096.1.1,,,,,,,CABO_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp143456_c0_seq4,2176,46.1857,0.49818144,97,757,,0,Q8K4K5,Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1),Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1),GO:0000137; GO:0000139; GO:0006893; GO:0005097; GO:0030424; GO:0007409; GO:0005856; GO:0031901; GO:0006887; GO:0032588,Golgi cis cisterna; Golgi membrane; Golgi to plasma membrane transport; Rab GTPase activator activity; axon; axonogenesis; cytoskeleton; early endosome membrane; exocytosis; trans-Golgi network membrane,PF08596;PF08366;,2.00E-180,CHOYP_LOC100378221.1.1,,,,,,,L2GL1_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] comp143457_c0_seq1,5057,48.329,0.62300915,615,270,,0,Q80TP3,"E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)","E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)",GO:0006281; GO:0003723; GO:0005737; GO:2000780; GO:1901315; GO:0005634; GO:0050847; GO:0042787; GO:0006974; GO:0004842; GO:0008270,DNA repair; RNA binding; cytoplasm; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleus; progesterone receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity; zinc ion binding,PF11547;PF00632;PF00658;,0,CHOYP_UBR5.1.1,,,,,,,UBR5_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of protein import into nucleus, translocation [GO:0033160]; progesterone receptor signaling pathway [GO:0050847]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]" comp143457_c0_seq2,289,47.7509,0.43376588,0,0,,1.00E-22,Q80TP3,"E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)","E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)",GO:0006281; GO:0003723; GO:0005737; GO:2000780; GO:1901315; GO:0005634; GO:0050847; GO:0042787; GO:0006974; GO:0004842; GO:0008270,DNA repair; RNA binding; cytoplasm; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleus; progesterone receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity; zinc ion binding,PF11547;PF00632;PF00658;,9.00E-23,CHOYP_UBR5.1.1,,,,,,,UBR5_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of protein import into nucleus, translocation [GO:0033160]; progesterone receptor signaling pathway [GO:0050847]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]" comp143458_c0_seq1,1898,46.1538,0.47784868,3,0,,2.00E-99,Q709C8,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp143458_c0_seq2,1083,46.9067,0.3738696,0,0,,1.00E-06,Q54LB8,Putative vacuolar protein sorting-associated protein 13A,Putative vacuolar protein sorting-associated protein 13A,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp143458_c0_seq3,1866,46.1415,0.45546473,0,0,,3.00E-07,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,,,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp143458_c0_seq4,2067,46.6376,0.42686,64,20,,2.00E-80,Q96RL7,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),GO:0006895; GO:0008219; GO:0031045; GO:0005622; GO:0007626; GO:0007399; GO:0008104; GO:0015031; GO:0035176,Golgi to endosome transport; cell death; dense core granule; intracellular; locomotory behavior; nervous system development; protein localization; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp143458_c0_seq5,1866,47.1597,0.42226723,19,4,,1.00E-12,O42926,Vacuolar protein sorting-associated protein 13b,Vacuolar protein sorting-associated protein 13b,GO:0005794; GO:0005768; GO:0006886; GO:0045324; GO:0045053,Golgi apparatus; endosome; intracellular protein transport; late endosome to vacuole transport; protein retention in Golgi apparatus,PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13B_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; vesicle-mediated transport [GO:0016192] comp143458_c0_seq8,351,46.4387,0.4773999,0,0,,2.00E-09,Q96RL7,Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein),GO:0006895; GO:0008219; GO:0031045; GO:0005622; GO:0007626; GO:0007399; GO:0008104; GO:0015031; GO:0035176,Golgi to endosome transport; cell death; dense core granule; intracellular; locomotory behavior; nervous system development; protein localization; protein transport; social behavior,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,7.00E-19,CHOYP_BRAFLDRAFT_226506.3.3,,,,,,,VP13A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176] comp143458_c0_seq9,319,46.395,0.35294464,0,0,,,,,,,,,8.00E-18,CHOYP_BRAFLDRAFT_226506.3.3,,,,,,,,, comp143459_c3_seq4,2206,37.4433,0.27498463,115,254,,,,,,,,,3.00E-26,CHOYP_LOC574700.1.1,,,,,,,,, comp143461_c0_seq2,2690,43.7918,0.60978403,214,433,,0,P21613,Kinesin heavy chain,Kinesin heavy chain,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,0,CHOYP_KINH.7.9,,,,,,,KINH_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),microtubule-based movement [GO:0007018] comp143461_c0_seq4,533,44.8405,0.41933329,4,0,,,,,,,,,3.00E-57,CHOYP_KINH.9.9,,,,,,,,, comp143461_c1_seq2,563,46.714,0.3992933,21,34,,8.00E-74,P21613,Kinesin heavy chain,Kinesin heavy chain,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,1.00E-69,CHOYP_KINH.6.9,,,,,,,KINH_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),microtubule-based movement [GO:0007018] comp143463_c0_seq1,1877,34.4699,1.11550137,162,1792,,2.00E-06,P51673,Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II),Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II),GO:0005829; GO:0005783; GO:0006869; GO:0005634; GO:0016918; GO:0001972; GO:0002138; GO:0019841; GO:0005215,cytosol; endoplasmic reticulum; lipid transport; nucleus; retinal binding; retinoic acid binding; retinoic acid biosynthetic process; retinol binding; transporter activity,PF00061;,,,1.00E-53,ruditapes2_lrc4378,,,,,RABP2_RAT,Rattus norvegicus (Rat),embryonic forelimb morphogenesis [GO:0035115]; lipid transport [GO:0006869]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; retinoic acid biosynthetic process [GO:0002138]; retinoic acid metabolic process [GO:0042573] comp143465_c0_seq2,4105,37.2229,0.55573281,3,37,,9.00E-89,P40782,Cyprosin (EC 3.4.23.-) (Fragment),Cyprosin (EC 3.4.23.-) (Fragment),GO:0004190; GO:0006629; GO:0006508,aspartic-type endopeptidase activity; lipid metabolic process; proteolysis,PF00026;PF05184;PF03489;,2.00E-140,CHOYP_CDC42.11.11,,,,,,,CYPR1_CYNCA,Cynara cardunculus (Cardoon),lipid metabolic process [GO:0006629] comp143465_c0_seq3,4011,36.9484,0.53339407,22,95,,9.00E-161,Q03168,Lysosomal aspartic protease (EC 3.4.23.-),Lysosomal aspartic protease (EC 3.4.23.-),GO:0004190; GO:0005764; GO:0006508,aspartic-type endopeptidase activity; lysosome; proteolysis,PF00026;,3.00E-151,CHOYP_CDC42.11.11,2.00E-99,ruditapes2_c128,,,,,ASPP_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp143468_c0_seq1,2487,44.1496,0.53653762,10,57,,5.00E-38,Q9H0F5,RING finger protein 38,E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38),GO:0008270,zinc ion binding,PF13639;,5.00E-56,CHOYP_RNF38.1.1,,,,,,,RNF38_HUMAN,Homo sapiens (Human),"male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]" comp143468_c0_seq2,1626,41.7589,0.50523486,0,3,,5.00E-39,Q9H0F5,RING finger protein 38,E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38),GO:0008270,zinc ion binding,PF13639;,4.00E-56,CHOYP_RNF38.1.1,,,,,,,RNF38_HUMAN,Homo sapiens (Human),"male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]" comp143468_c0_seq3,1859,41.5815,0.49437757,0,0,,3.00E-37,Q08CG8,RING finger protein 44,RING finger protein 44,GO:0008270,zinc ion binding,PF13639;,,,,,,,,,RNF44_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of transcription, DNA-templated [GO:0006355]" comp143468_c0_seq4,3141,43.2346,0.46386457,0,20,,,,,,,,,4.00E-53,CHOYP_LOC100376112.1.1,,,,,,,,, comp143468_c0_seq9,2283,44.5905,0.54640087,0,6,,3.00E-38,Q9H0F5,RING finger protein 38,E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38),GO:0008270,zinc ion binding,PF13639;,5.00E-56,CHOYP_RNF38.1.1,,,,,,,RNF38_HUMAN,Homo sapiens (Human),"male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]" comp143469_c1_seq1,660,41.9697,0.31356808,41,33,,3.00E-19,Q8C3Y4,Kinetochore-associated protein 1,Kinetochore-associated protein 1,GO:0051301; GO:0000777; GO:0005737; GO:0005828; GO:0007067; GO:0007093; GO:0005634; GO:0000922,cell division; condensed chromosome kinetochore; cytoplasm; kinetochore microtubule; mitosis; mitotic cell cycle checkpoint; nucleus; spindle pole,PF10493;,,,,,,,,,KNTC1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067] comp143469_c2_seq1,723,46.6113,0.30606696,13,14,,9.00E-15,P50748,Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),GO:0051301; GO:0000777; GO:0005829; GO:0005828; GO:0007067; GO:0000278; GO:0007093; GO:0005634; GO:0006461; GO:0007096; GO:0000922,cell division; condensed chromosome kinetochore; cytosol; kinetochore microtubule; mitosis; mitotic cell cycle; mitotic cell cycle checkpoint; nucleus; protein complex assembly; regulation of exit from mitosis; spindle pole,PF10493;,,,,,,,,,KNTC1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062] comp143469_c3_seq2,919,45.1578,0.19236153,0,0,,8.00E-35,P50748,Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),GO:0051301; GO:0000777; GO:0005829; GO:0005828; GO:0007067; GO:0000278; GO:0007093; GO:0005634; GO:0006461; GO:0007096; GO:0000922,cell division; condensed chromosome kinetochore; cytosol; kinetochore microtubule; mitosis; mitotic cell cycle; mitotic cell cycle checkpoint; nucleus; protein complex assembly; regulation of exit from mitosis; spindle pole,PF10493;,,,,,,,,,KNTC1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062] comp143469_c3_seq5,1296,44.3673,0.28246841,37,59,,2.00E-45,Q8C3Y4,Kinetochore-associated protein 1,Kinetochore-associated protein 1,GO:0051301; GO:0000777; GO:0005737; GO:0005828; GO:0007067; GO:0007093; GO:0005634; GO:0000922,cell division; condensed chromosome kinetochore; cytoplasm; kinetochore microtubule; mitosis; mitotic cell cycle checkpoint; nucleus; spindle pole,PF10493;,,,,,,,,,KNTC1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067] comp143470_c0_seq1,1400,39,0.47569596,260,134,,1.00E-12,Q4PA50,Clustered mitochondria protein homolog (Protein TIF31 homolog),Clustered mitochondria protein homolog (Protein TIF31 homolog),GO:0005737; GO:0048312,cytoplasm; intracellular distribution of mitochondria,PF13236;PF15044;PF12807;PF13374;,,,1.00E-77,ruditapes_c25549,,,,,CLU_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus),intracellular distribution of mitochondria [GO:0048312] comp143470_c1_seq1,1090,45.6881,0.58445529,250,141,,1.00E-137,B0W2S0,Clustered mitochondria protein homolog,Clustered mitochondria protein homolog,GO:0005737; GO:0048312,cytoplasm; intracellular distribution of mitochondria,PF13236;PF15044;PF05303;PF12807;PF13374;,6.00E-83,CHOYP_LOC663660.1.1,,,,,,,CLU_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),intracellular distribution of mitochondria [GO:0048312] comp143470_c1_seq2,2249,45.5758,0.5491238,446,216,,0,B0W2S0,Clustered mitochondria protein homolog,Clustered mitochondria protein homolog,GO:0005737; GO:0048312,cytoplasm; intracellular distribution of mitochondria,PF13236;PF15044;PF05303;PF12807;PF13374;,0,CHOYP_CLU.1.1,,,,,,,CLU_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),intracellular distribution of mitochondria [GO:0048312] comp143472_c0_seq1,4542,42.3382,0.36833388,101,526,,0,Q10490,"Putative leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)","Putative leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)",GO:0005524; GO:0002161; GO:0002181; GO:0005829; GO:0004823; GO:0006429; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; cytoplasmic translation; cytosol; leucine-tRNA ligase activity; leucyl-tRNA aminoacylation; regulation of translational fidelity,PF08264;PF00133;,,,,,,,,,SYLC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translation [GO:0002181]; leucyl-tRNA aminoacylation [GO:0006429] comp143472_c0_seq2,4494,42.4344,0.36574371,20,290,,0,Q9P2J5,"Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)","Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)",GO:0005524; GO:0002161; GO:0005829; GO:0004823; GO:0006429; GO:0006450; GO:0006418,ATP binding; aminoacyl-tRNA editing activity; cytosol; leucine-tRNA ligase activity; leucyl-tRNA aminoacylation; regulation of translational fidelity; tRNA aminoacylation for protein translation,PF08264;PF00133;,0,CHOYP_BRAFLDRAFT_63907.1.1,,,,,,,SYLC_HUMAN,Homo sapiens (Human),leucyl-tRNA aminoacylation [GO:0006429]; tRNA aminoacylation for protein translation [GO:0006418] comp143473_c0_seq1,439,37.8132,0.51282317,2,0,,4.00E-10,Q8D8G1,Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C),Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C),GO:0003723; GO:0009982; GO:0001522; GO:0006364,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; rRNA processing,PF00849;PF01479;,,,,,,,,,RLUC_VIBVU,Vibrio vulnificus (strain CMCP6),pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364] comp143473_c1_seq1,3030,33.7624,0.33673653,6,15,,3.00E-31,Q08C69,RNA pseudouridylate synthase domain-containing protein 1,RNA pseudouridylate synthase domain-containing protein 1,GO:0003723; GO:0009982; GO:0001522,RNA binding; pseudouridine synthase activity; pseudouridine synthesis,PF00849;,,,,,,,,,RUSD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),tRNA pseudouridine synthesis [GO:0031119] comp143476_c0_seq1,1667,36.7127,0.69533455,622,2486,,6.00E-07,Q9ESN4,Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin),Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin),GO:0005581; GO:0005576; GO:0050807,collagen; extracellular region; regulation of synapse organization,PF00386;PF01391;,,,,,,,,,C1QL3_MOUSE,Mus musculus (Mouse),regulation of synapse organization [GO:0050807] comp143480_c0_seq1,1474,39.1452,0.85787026,254,1937,,9.00E-42,Q9Y2F9,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,,,,,,,,,BTBD3_HUMAN,Homo sapiens (Human),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp143482_c0_seq1,3968,45.2369,0.62922619,63,59,,0,O93574,Reelin (EC 3.4.21.-) (Fragment),Reelin (EC 3.4.21.-) (Fragment),GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0005615; GO:0010001; GO:0046872; GO:0001764; GO:0018108; GO:0045860; GO:0051057; GO:0004712; GO:0005578; GO:0006508; GO:0048265; GO:0008236; GO:0021511; GO:0021517,axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; extracellular space; glial cell differentiation; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of protein kinase activity; positive regulation of small GTPase mediated signal transduction; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development,PF07974;PF12661;,,,,,,,,,RELN_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517] comp143482_c0_seq2,3824,45.4236,0.63738786,52,42,,0,O93574,Reelin (EC 3.4.21.-) (Fragment),Reelin (EC 3.4.21.-) (Fragment),GO:0007411; GO:0007155; GO:0021800; GO:0005737; GO:0030425; GO:0005615; GO:0010001; GO:0046872; GO:0001764; GO:0018108; GO:0045860; GO:0051057; GO:0004712; GO:0005578; GO:0006508; GO:0048265; GO:0008236; GO:0021511; GO:0021517,axon guidance; cell adhesion; cerebral cortex tangential migration; cytoplasm; dendrite; extracellular space; glial cell differentiation; metal ion binding; neuron migration; peptidyl-tyrosine phosphorylation; positive regulation of protein kinase activity; positive regulation of small GTPase mediated signal transduction; protein serine/threonine/tyrosine kinase activity; proteinaceous extracellular matrix; proteolysis; response to pain; serine-type peptidase activity; spinal cord patterning; ventral spinal cord development,PF07974;PF12661;,1.00E-35,CHOYP_RELN.3.4,7.00E-80,ruditapes2_c2564,,,,,RELN_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517] comp143483_c1_seq1,3737,42.2799,0.48393091,450,300,,7.00E-73,O75665,Oral-facial-digital syndrome 1 protein (Protein 71-7A),Oral-facial-digital syndrome 1 protein (Protein 71-7A),GO:0000086; GO:0043014; GO:0005814; GO:0005929; GO:0035083; GO:0060271; GO:0005829; GO:0060287; GO:0043015; GO:0005932; GO:0005634,G2/M transition of mitotic cell cycle; alpha-tubulin binding; centriole; cilium; cilium axoneme assembly; cilium morphogenesis; cytosol; epithelial cilium movement involved in determination of left/right asymmetry; gamma-tubulin binding; microtubule basal body; nucleus,PF16045;,6.00E-45,CHOYP_OFD1.1.1,,,,,,,OFD1_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; G2/M transition of mitotic cell cycle [GO:0000086] comp143485_c0_seq1,4745,41.0116,0.53331095,163,682,,0,Q805F9,DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor),DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor),GO:0031464; GO:0031465; GO:0003677; GO:0006281; GO:0005737; GO:0005654; GO:0043161; GO:0016567,Cul4A-RING ubiquitin ligase complex; Cul4B-RING ubiquitin ligase complex; DNA binding; DNA repair; cytoplasm; nucleoplasm; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination,PF03178;,0,CHOYP_DDB1.1.1,,,,,,,DDB1_CHICK,Gallus gallus (Chicken),DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] comp143485_c0_seq2,4153,40.5008,0.48983034,282,901,,4.00E-35,Q9UTT2,Pre-mRNA-splicing factor prp12 (Pre-mRNA-processing protein 12) (Spliceosome-associated protein 130),Pre-mRNA-splicing factor prp12 (Pre-mRNA-processing protein 12) (Spliceosome-associated protein 130),GO:0030620; GO:0005686; GO:0007049; GO:0045292; GO:0005681; GO:0000245,"U2 snRNA binding; U2 snRNP; cell cycle; mRNA cis splicing, via spliceosome; spliceosomal complex; spliceosomal complex assembly",PF03178;,,,,,,,,,RSE1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA cis splicing, via spliceosome [GO:0045292]; spliceosomal complex assembly [GO:0000245]" comp143486_c0_seq1,2036,38.5069,0.48022644,860,1702,,5.00E-169,Q29RH4,THO complex subunit 3 (Tho3),THO complex subunit 3 (Tho3),GO:0003723; GO:0008380; GO:0006397; GO:0051028; GO:0005634,RNA binding; RNA splicing; mRNA processing; mRNA transport; nucleus,PF12894;PF08662;PF00400;,2.00E-135,CHOYP_BRAFLDRAFT_128129.1.1,,,,,,,THOC3_BOVIN,Bos taurus (Bovine),mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp143487_c0_seq1,3051,46.6077,0.31427036,0,0,,9.00E-35,Q2T9I5,RNA-binding protein 26 (RNA-binding motif protein 26),RNA-binding protein 26 (RNA-binding motif protein 26),GO:0003723; GO:0006397; GO:0046872; GO:0010923; GO:0000166,RNA binding; mRNA processing; metal ion binding; negative regulation of phosphatase activity; nucleotide binding,PF01480;PF00076;,,,,,,,,,RBM26_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; negative regulation of phosphatase activity [GO:0010923] comp143487_c0_seq2,3092,46.5071,0.32338714,12,22,,5.00E-23,Q9P2N5,RNA-binding protein 27 (RNA-binding motif protein 27),RNA-binding protein 27 (RNA-binding motif protein 27),GO:0003723; GO:0005737; GO:0006397; GO:0046872; GO:0016607; GO:0000166; GO:0005634,RNA binding; cytoplasm; mRNA processing; metal ion binding; nuclear speck; nucleotide binding; nucleus,PF01480;PF00642;,2.00E-30,CHOYP_LOC100565366.1.1,,,,,,,RBM27_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397] comp143487_c0_seq4,644,39.7516,0.59084112,57,60,,3.00E-11,Q9USP9,Uncharacterized RNA-binding protein C902.04,Uncharacterized RNA-binding protein C902.04,GO:0003723; GO:0000166; GO:0005634,RNA binding; nucleotide binding; nucleus,PF01480;PF00076;,,,,,,,,,YHP4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mRNA processing [GO:0006397]; regulation of heterochromatin domain assembly [GO:1902802] comp143487_c0_seq6,970,46.1856,0.4087442,9,12,,1.00E-08,Q2T9I5,RNA-binding protein 26 (RNA-binding motif protein 26),RNA-binding protein 26 (RNA-binding motif protein 26),GO:0003723; GO:0006397; GO:0046872; GO:0010923; GO:0000166,RNA binding; mRNA processing; metal ion binding; negative regulation of phosphatase activity; nucleotide binding,PF01480;PF00076;,,,,,,,,,RBM26_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; negative regulation of phosphatase activity [GO:0010923] comp143488_c1_seq12,1902,44.9001,0.56117593,0,0,,0,Q9I7F7,Tyrosine-protein kinase PR2 (EC 2.7.10.2),Tyrosine-protein kinase PR2 (EC 2.7.10.2),GO:0005524; GO:0004715; GO:0004713; GO:0035071,ATP binding; non-membrane spanning protein tyrosine kinase activity; protein tyrosine kinase activity; salivary gland cell autophagic cell death,PF00786;PF07714;PF07653;,7.00E-174,CHOYP_ISCW_ISCW020028.1.1,,,,,,,PR2_DROME,Drosophila melanogaster (Fruit fly),cell differentiation [GO:0030154]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp143488_c1_seq2,1736,45.3917,0.56754709,0,0,,0,Q9I7F7,Tyrosine-protein kinase PR2 (EC 2.7.10.2),Tyrosine-protein kinase PR2 (EC 2.7.10.2),GO:0005524; GO:0004715; GO:0004713; GO:0035071,ATP binding; non-membrane spanning protein tyrosine kinase activity; protein tyrosine kinase activity; salivary gland cell autophagic cell death,PF00786;PF07714;PF07653;,6.00E-174,CHOYP_ISCW_ISCW020028.1.1,,,,,,,PR2_DROME,Drosophila melanogaster (Fruit fly),cell differentiation [GO:0030154]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp143488_c1_seq3,2065,45.23,0.53616344,0,0,,4.00E-79,Q07912,Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2),Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2),GO:0005524; GO:0005095; GO:0070436; GO:0050699; GO:0005912; GO:0030424; GO:0007166; GO:0030136; GO:0005905; GO:0030659; GO:0030425; GO:0006897; GO:0005768; GO:0005154; GO:0030426; GO:0046872; GO:0043025; GO:0004715; GO:0005634; GO:0050731; GO:0004674; GO:0004712; GO:2000369; GO:0007264,ATP binding; GTPase inhibitor activity; Grb2-EGFR complex; WW domain binding; adherens junction; axon; cell surface receptor signaling pathway; clathrin-coated vesicle; coated pit; cytoplasmic vesicle membrane; dendrite; endocytosis; endosome; epidermal growth factor receptor binding; growth cone; metal ion binding; neuronal cell body; non-membrane spanning protein tyrosine kinase activity; nucleus; positive regulation of peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; regulation of clathrin-mediated endocytosis; small GTPase mediated signal transduction,PF09027;PF11555;PF07714;PF14604;,7.00E-79,CHOYP_LOC100168786.1.1,,,,,,,ACK1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of clathrin-mediated endocytosis [GO:2000369]; small GTPase mediated signal transduction [GO:0007264]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp143488_c1_seq6,1198,45.0751,0.47707349,3,19,,4.00E-16,P55245,Epidermal growth factor receptor (EC 2.7.10.1) (Fragment),Epidermal growth factor receptor (EC 2.7.10.1),GO:0005524; GO:0000139; GO:0016323; GO:0000902; GO:0008283; GO:0016337; GO:0071392; GO:0021795; GO:0003682; GO:0048546; GO:0001892; GO:0030139; GO:0005789; GO:0005768; GO:0010008; GO:0005006; GO:0001942; GO:0045121; GO:0060571; GO:0043066; GO:0042177; GO:0030235; GO:0031965; GO:0005634; GO:0048471; GO:0045739; GO:0045740; GO:0070374; GO:0043406; GO:0035413; GO:0030335; GO:0031659; GO:0050679; GO:0048146; GO:0045429; GO:0051897; GO:0001934; GO:0045944; GO:0046777; GO:0004713; GO:0050999; GO:0050730; GO:0070141; GO:0007435,ATP binding; Golgi membrane; basolateral plasma membrane; cell morphogenesis; cell proliferation; cell-cell adhesion; cellular response to estradiol stimulus; cerebral cortex cell migration; chromatin binding; digestive tract morphogenesis; embryonic placenta development; endocytic vesicle; endoplasmic reticulum membrane; endosome; endosome membrane; epidermal growth factor-activated receptor activity; hair follicle development; membrane raft; morphogenesis of an epithelial fold; negative regulation of apoptotic process; negative regulation of protein catabolic process; nitric-oxide synthase regulator activity; nuclear membrane; nucleus; perinuclear region of cytoplasm; positive regulation of DNA repair; positive regulation of DNA replication; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAP kinase activity; positive regulation of catenin import into nucleus; positive regulation of cell migration; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of nitric oxide biosynthetic process; positive regulation of protein kinase B signaling cascade; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; protein tyrosine kinase activity; regulation of nitric-oxide synthase activity; regulation of peptidyl-tyrosine phosphorylation; response to UV-A; salivary gland morphogenesis,PF00757;PF14843;PF07714;PF01030;,,,,,,,,,EGFR_MACMU,Macaca mulatta (Rhesus macaque),cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; epidermal growth factor receptor signaling pathway [GO:0007173]; learning or memory [GO:0007611]; positive regulation of cell growth [GO:0030307]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp143488_c1_seq7,869,45.3395,0.51593509,0,0,,1.00E-22,Q03351,NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase),NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase),GO:0005524; GO:0000139; GO:0000187; GO:0032856; GO:0032148; GO:0071300; GO:0090102; GO:0005887; GO:0042490; GO:0019056; GO:0048712; GO:0060548; GO:0001933; GO:0048665; GO:0001764; GO:0005030; GO:0018108; GO:0005886; GO:2000251; GO:0048691; GO:0030335; GO:0008284; GO:0010628; GO:0033138; GO:0050927; GO:0046777; GO:0048678; GO:0051412; GO:0045471; GO:0004714; GO:0007169,ATP binding; Golgi membrane; activation of MAPK activity; activation of Ras GTPase activity; activation of protein kinase B activity; cellular response to retinoic acid; cochlea development; integral to plasma membrane; mechanoreceptor differentiation; modulation by virus of host transcription; negative regulation of astrocyte differentiation; negative regulation of cell death; negative regulation of protein phosphorylation; neuron fate specification; neuron migration; neurotrophin receptor activity; peptidyl-tyrosine phosphorylation; plasma membrane; positive regulation of actin cytoskeleton reorganization; positive regulation of axon extension involved in regeneration; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of gene expression; positive regulation of peptidyl-serine phosphorylation; positive regulation of positive chemotaxis; protein autophosphorylation; response to axon injury; response to corticosterone stimulus; response to ethanol; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07679;PF00047;PF13855;PF01462;PF07714;PF16920;,,,,,,,,,NTRK3_RAT,Rattus norvegicus (Rat),activation of adenylate cyclase activity [GO:0007190]; activation of GTPase activity [GO:0090630]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; cochlea development [GO:0090102]; heart development [GO:0007507]; lens fiber cell differentiation [GO:0070306]; mechanoreceptor differentiation [GO:0042490]; modulation by virus of host transcription [GO:0019056]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell death [GO:0060548]; negative regulation of protein phosphorylation [GO:0001933]; neuron fate specification [GO:0048665]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; Ras protein signal transduction [GO:0007265]; response to axon injury [GO:0048678]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264] comp143488_c1_seq8,1204,45.2658,0.81199517,0,0,,,,,,,,,,,2.00E-36,ruditapes_c18815,,,,,,, comp143489_c0_seq1,1095,44.9315,0.42089832,5,0,,1.00E-142,Q6ZQB6,Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.21) (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2),Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.21) (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2),GO:0005524; GO:0003993; GO:0005829; GO:0033857; GO:0052723; GO:0052724; GO:0000832; GO:0006020; GO:0000827,"ATP binding; acid phosphatase activity; cytosol; diphosphoinositol-pentakisphosphate kinase activity; inositol hexakisphosphate 1-kinase activity; inositol hexakisphosphate 3-kinase activity; inositol hexakisphosphate 5-kinase activity; inositol metabolic process; inositol-1,3,4,5,6-pentakisphosphate kinase activity",PF00328;,,,,,,,,,VIP2_MOUSE,Mus musculus (Mouse),inositol metabolic process [GO:0006020] comp143489_c0_seq2,1772,42.3251,0.4331196,0,0,,,,,,,,,5.00E-131,CHOYP_LOC100863008.1.2,,,,,,,,, comp143489_c0_seq6,3513,44.4919,0.53293006,0,0,,0,Q9VR59,Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24) (InsP6 and PP-IP5 kinase),Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24) (InsP6 and PP-IP5 kinase),GO:0005524; GO:0005829; GO:0033857; GO:0052723; GO:0052724; GO:0000832; GO:0006020; GO:0000827,"ATP binding; cytosol; diphosphoinositol-pentakisphosphate kinase activity; inositol hexakisphosphate 1-kinase activity; inositol hexakisphosphate 3-kinase activity; inositol hexakisphosphate 5-kinase activity; inositol metabolic process; inositol-1,3,4,5,6-pentakisphosphate kinase activity",PF00328;,0,CHOYP_VIP2.1.1,,,,,,,VIP1_DROME,Drosophila melanogaster (Fruit fly),inositol metabolic process [GO:0006020] comp143489_c0_seq7,3471,44.5693,0.52684096,0,0,,0,Q9VR59,Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24) (InsP6 and PP-IP5 kinase),Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24) (InsP6 and PP-IP5 kinase),GO:0005524; GO:0005829; GO:0033857; GO:0052723; GO:0052724; GO:0000832; GO:0006020; GO:0000827,"ATP binding; cytosol; diphosphoinositol-pentakisphosphate kinase activity; inositol hexakisphosphate 1-kinase activity; inositol hexakisphosphate 3-kinase activity; inositol hexakisphosphate 5-kinase activity; inositol metabolic process; inositol-1,3,4,5,6-pentakisphosphate kinase activity",PF00328;,,,,,,,,,VIP1_DROME,Drosophila melanogaster (Fruit fly),inositol metabolic process [GO:0006020] comp143489_c0_seq8,3141,44.4444,0.52350531,0,0,,,,,,,,,0,CHOYP_VIP2.1.1,2.00E-61,ruditapes_c18103,,,,,,, comp143491_c0_seq2,562,38.79,0.95286753,0,0,,9.00E-07,B2RPV6,Multimerin-1,Multimerin-1,GO:0005576,extracellular region,PF00386;PF00008;PF07546;,,,,,,,,,MMRN1_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596] comp143491_c0_seq3,574,37.4564,0.7033046,0,34,,4.00E-07,Q9ESN4,Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin),Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin),GO:0005581; GO:0005576; GO:0050807,collagen; extracellular region; regulation of synapse organization,PF00386;PF01391;,,,,,,,,,C1QL3_MOUSE,Mus musculus (Mouse),regulation of synapse organization [GO:0050807] comp143491_c0_seq7,635,38.7402,0.84350342,0,13,,1.00E-07,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp143492_c0_seq1,2765,39.2405,0.33842456,148,767,,3.00E-131,Q6R3M4,DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B),DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B),GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0046872; GO:0005634,DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; metal ion binding; nucleus,PF00817;PF11799;PF11798;,3.00E-35,CHOYP_POLI.1.1,,,,,,,POLI_MOUSE,Mus musculus (Mouse),cellular response to UV-C [GO:0071494]; DNA replication [GO:0006260]; translesion synthesis [GO:0019985] comp143496_c0_seq1,2089,42.8435,0.45410917,74,79,,5.00E-173,P54813,ATP-dependent zinc metalloprotease YME1 homolog (EC 3.4.24.-),ATP-dependent zinc metalloprotease YME1 homolog (EC 3.4.24.-),GO:0005524; GO:0016021; GO:0046872; GO:0004222; GO:0017111; GO:0006508,ATP binding; integral to membrane; metal ion binding; metalloendopeptidase activity; nucleoside-triphosphatase activity; proteolysis,PF00004;PF01434;,,,,,,,,,YME1_CAEEL,Caenorhabditis elegans,misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion organization [GO:0007005] comp143496_c0_seq3,2005,43.3915,0.39885226,34,96,,6.00E-70,Q7TT47,Paraplegin (EC 3.4.24.-),Paraplegin (EC 3.4.24.-),GO:0005524; GO:0016021; GO:0004222; GO:0031966; GO:0017111; GO:0006508; GO:0008270,ATP binding; integral to membrane; metalloendopeptidase activity; mitochondrial membrane; nucleoside-triphosphatase activity; proteolysis; zinc ion binding,PF00004;PF06480;PF01434;,1.00E-19,CHOYP_AAEL_AAEL010241.1.1,,,,,,,SPG7_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155]; mitochondrion organization [GO:0007005]; nervous system development [GO:0007399]; proteolysis [GO:0006508] comp143498_c0_seq1,2787,36.9214,0.56956085,1376,415,,0,Q5M7G4,Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8),Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8),GO:0005524; GO:0004017; GO:0004127; GO:0005829; GO:0004550; GO:0009142,ATP binding; adenylate kinase activity; cytidylate kinase activity; cytosol; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process,,0,CHOYP_LOC100368938.2.2,,,,,,,KAD8_XENLA,Xenopus laevis (African clawed frog),nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp143501_c0_seq1,2416,41.3079,0.54823915,30,17,,0,P50096,Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I),Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I),GO:0003677; GO:0006177; GO:0003938; GO:0030554; GO:0005737; GO:0046651; GO:0046872; GO:0005634; GO:0006164,DNA binding; GMP biosynthetic process; IMP dehydrogenase activity; adenyl nucleotide binding; cytoplasm; lymphocyte proliferation; metal ion binding; nucleus; purine nucleotide biosynthetic process,PF00571;PF00478;,,,3.00E-50,ruditapes_c14371,,,,,IMDH1_MOUSE,Mus musculus (Mouse),GMP biosynthetic process [GO:0006177]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; response to cold [GO:0009409]; retina development in camera-type eye [GO:0060041] comp143501_c0_seq2,2442,41.5643,0.52755472,23,43,,0,P50096,Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I),Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I),GO:0003677; GO:0006177; GO:0003938; GO:0030554; GO:0005737; GO:0046651; GO:0046872; GO:0005634; GO:0006164,DNA binding; GMP biosynthetic process; IMP dehydrogenase activity; adenyl nucleotide binding; cytoplasm; lymphocyte proliferation; metal ion binding; nucleus; purine nucleotide biosynthetic process,PF00571;PF00478;,0,CHOYP_IMDH3.1.1,,,,,,,IMDH1_MOUSE,Mus musculus (Mouse),GMP biosynthetic process [GO:0006177]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; response to cold [GO:0009409]; retina development in camera-type eye [GO:0060041] comp143502_c0_seq1,4067,40.2754,0.30891199,931,4448,,0,P28668,Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)],Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)],GO:0005524; GO:0003723; GO:0005737; GO:0004818; GO:0006424; GO:0004827; GO:0006433,ATP binding; RNA binding; cytoplasm; glutamate-tRNA ligase activity; glutamyl-tRNA aminoacylation; proline-tRNA ligase activity; prolyl-tRNA aminoacylation,PF14497;PF03129;PF09180;PF00749;PF03950;PF00587;PF00458;,0,CHOYP_LOC100376708.2.2,4.00E-77,ruditapes_c13376,,,,,SYEP_DROME,Drosophila melanogaster (Fruit fly),glutamyl-tRNA aminoacylation [GO:0006424]; prolyl-tRNA aminoacylation [GO:0006433] comp143502_c0_seq2,1399,44.8892,0.53198618,0,0,,3.00E-13,B1LBX4,Glutamate--tRNA ligase 2 (EC 6.1.1.17) (Glutamyl-tRNA synthetase 2) (GluRS 2),Glutamate--tRNA ligase 2 (EC 6.1.1.17) (Glutamyl-tRNA synthetase 2) (GluRS 2),GO:0005524; GO:0005737; GO:0004818; GO:0006424; GO:0000049,ATP binding; cytoplasm; glutamate-tRNA ligase activity; glutamyl-tRNA aminoacylation; tRNA binding,PF00749;,,,,,,,,,SYE2_THESQ,Thermotoga sp. (strain RQ2),glutamyl-tRNA aminoacylation [GO:0006424] comp143502_c0_seq5,1399,44.8177,0.54717902,25,20,,1.00E-95,O13775,"Probable glutamate--tRNA ligase, cytoplasmic (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)","Probable glutamate--tRNA ligase, cytoplasmic (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)",GO:0005524; GO:0003723; GO:0002181; GO:0005829; GO:0004818; GO:0006424; GO:0005634,ATP binding; RNA binding; cytoplasmic translation; cytosol; glutamate-tRNA ligase activity; glutamyl-tRNA aminoacylation; nucleus,PF00749;PF03950;,2.00E-109,CHOYP_EPRS.1.1,,,,,,,SYEC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic translation [GO:0002181]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424] comp143502_c0_seq6,889,42.7447,0.4025902,155,188,,6.00E-138,Q8CGC7,Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)],Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)],GO:0005524; GO:0035613; GO:0071346; GO:0005737; GO:0004818; GO:0006424; GO:0017148; GO:0004827; GO:0006433; GO:0030529,ATP binding; RNA stem-loop binding; cellular response to interferon-gamma; cytoplasm; glutamate-tRNA ligase activity; glutamyl-tRNA aminoacylation; negative regulation of translation; proline-tRNA ligase activity; prolyl-tRNA aminoacylation; ribonucleoprotein complex,PF00043;PF03129;PF09180;PF00749;PF03950;PF00587;PF00458;,,,,,,,,,SYEP_MOUSE,Mus musculus (Mouse),cellular response to interferon-gamma [GO:0071346]; glutamyl-tRNA aminoacylation [GO:0006424]; negative regulation of translation [GO:0017148]; prolyl-tRNA aminoacylation [GO:0006433] comp143505_c0_seq1,1076,41.5428,0.67082638,159,601,,1.00E-126,P0C872,JmjC domain-containing protein 7 (Jumonji domain-containing protein 7),JmjC domain-containing protein 7 (Jumonji domain-containing protein 7),,,,3.00E-54,CHOYP_BRAFLDRAFT_90706.1.2,,,,,,,JMJD7_MOUSE,Mus musculus (Mouse), comp143506_c0_seq1,1354,42.0236,0.67312506,13859,41688,,2.00E-115,O01666,"ATP synthase subunit gamma, mitochondrial (F-ATPase gamma subunit)","ATP synthase subunit gamma, mitochondrial (F-ATPase gamma subunit)",GO:0015986; GO:0005811; GO:0005743; GO:0006909; GO:0046933; GO:0045261; GO:0046961,"ATP synthesis coupled proton transport; lipid particle; mitochondrial inner membrane; phagocytosis; proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATP synthase complex, catalytic core F(1); proton-transporting ATPase activity, rotational mechanism",PF00231;,7.00E-33,CHOYP_ATP5C1.1.1,3.00E-123,ruditapes2_c26,,,,,ATPG_DROME,Drosophila melanogaster (Fruit fly),ATP synthesis coupled proton transport [GO:0015986]; phagocytosis [GO:0006909]; proton transport [GO:0015992] comp143506_c1_seq10,1225,41.3061,0.79726611,0,0,,2.00E-16,O64515,Organic cation/carnitine transporter 2 (AtOCT2),Organic cation/carnitine transporter 2 (AtOCT2),GO:0005524; GO:0016021; GO:0006811; GO:0009705; GO:0022857,ATP binding; integral to membrane; ion transport; plant-type vacuole membrane; transmembrane transporter activity,PF00083;,,,,,,,,,OCT2_ARATH,Arabidopsis thaliana (Mouse-ear cress),ion transport [GO:0006811] comp143506_c1_seq11,1270,42.126,0.82579147,4,25,,2.00E-50,Q9WTN6,Solute carrier family 22 member 21 (Organic cation/carnitine transporter 3) (Solute carrier family 22 member 9),Solute carrier family 22 member 21 (Organic cation/carnitine transporter 3) (Solute carrier family 22 member 9),GO:0005524; GO:0015226; GO:0016021; GO:0031231,ATP binding; carnitine transmembrane transporter activity; integral to membrane; intrinsic to peroxisomal membrane,PF00083;,,,,,,,,,S22AL_MOUSE,Mus musculus (Mouse),carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879] comp143506_c1_seq6,3293,38.0504,0.79100573,474,2490,,9.00E-69,Q9H015,Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (Organic cation/carnitine transporter 1),Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (Organic cation/carnitine transporter 1),GO:0005524; GO:0016324; GO:0007589; GO:0009437; GO:0015226; GO:0015491; GO:0005887; GO:0005739; GO:0000166; GO:0008513; GO:0006814; GO:0015293; GO:0006641,ATP binding; apical plasma membrane; body fluid secretion; carnitine metabolic process; carnitine transmembrane transporter activity; cation:cation antiporter activity; integral to plasma membrane; mitochondrion; nucleotide binding; secondary active organic cation transmembrane transporter activity; sodium ion transport; symporter activity; triglyceride metabolic process,PF00083;,,,,,,,,,S22A4_HUMAN,Homo sapiens (Human),body fluid secretion [GO:0007589]; carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; organic cation transport [GO:0015695]; quaternary ammonium group transport [GO:0015697]; sodium ion transport [GO:0006814]; triglyceride metabolic process [GO:0006641] comp143506_c1_seq7,3338,38.3463,0.79247132,356,2509,,7.00E-90,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp143506_c3_seq1,1778,42.2385,0.4609805,75,954,,1.00E-170,Q9H3G5,"Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)","Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)",GO:0006508; GO:0004185,proteolysis; serine-type carboxypeptidase activity,PF00450;,1.00E-139,CHOYP_CPVL.1.2,,,,,,,CPVL_HUMAN,Homo sapiens (Human),proteolysis involved in cellular protein catabolic process [GO:0051603] comp143507_c3_seq2,2687,38.9282,0.38890048,27,121,,4.00E-102,Q9BV44,THUMP domain-containing protein 3,THUMP domain-containing protein 3,GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF02926;PF01170;,,,,,,,,,THUM3_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp143507_c3_seq3,2236,38.0143,0.34851029,0,9,,2.00E-89,P97770,THUMP domain-containing protein 3 (GtROSA26asSor),THUMP domain-containing protein 3 (GtROSA26asSor),GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF02926;PF01170;,1.00E-13,CHOYP_THUM3.1.1,,,,,,,THUM3_MOUSE,Mus musculus (Mouse),tRNA methylation [GO:0030488] comp143508_c1_seq1,4009,40.2345,0.86426144,28,417,,4.00E-67,P82198,Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3),Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3),GO:0001525; GO:0007155; GO:0050840; GO:0030198; GO:0005615; GO:0070062; GO:0005578,angiogenesis; cell adhesion; extracellular matrix binding; extracellular matrix organization; extracellular space; extracellular vesicular exosome; proteinaceous extracellular matrix,PF02469;,,,4.00E-33,ruditapes2_c222,,,,,BGH3_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198] comp143508_c1_seq2,4021,40.2139,0.85632147,3,389,,7.00E-65,O11780,Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP),Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,PF02469;,,,,,,,,,BGH3_PIG,Sus scrofa (Pig),cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; extracellular matrix organization [GO:0030198] comp143509_c0_seq2,1085,41.3825,0.48765196,243,62,,4.00E-34,Q9C5Y4,Structural maintenance of chromosomes protein 2-1 (AtSMC2-1) (Chromosome-associated protein E-1) (AtCAP-E1) (Protein TITAN 3),Structural maintenance of chromosomes protein 2-1 (AtSMC2-1) (Chromosome-associated protein E-1) (AtCAP-E1) (Protein TITAN 3),GO:0005524; GO:0006310; GO:0006281; GO:0051301; GO:0000796; GO:0007126; GO:0007076; GO:0005634; GO:0007062; GO:0005215,ATP binding; DNA recombination; DNA repair; cell division; condensin complex; meiosis; mitotic chromosome condensation; nucleus; sister chromatid cohesion; transporter activity,PF06470;PF02463;,0,CHOYP_SMC3.1.1,,,,,,,SMC21_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; mitotic chromosome condensation [GO:0007076] comp143509_c1_seq1,2623,42.5086,0.37095783,80,45,,0,O93309,Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3),Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3),GO:0005524; GO:0006281; GO:0051301; GO:0000785; GO:0051276; GO:0000775; GO:0007126; GO:0030893; GO:0007067; GO:0005634; GO:0006275,"ATP binding; DNA repair; cell division; chromatin; chromosome organization; chromosome, centromeric region; meiosis; meiotic cohesin complex; mitosis; nucleus; regulation of DNA replication",PF06470;PF02463;,,,,,,,,,SMC3_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid cohesion [GO:0007064]; regulation of DNA replication [GO:0006275] comp143509_c1_seq2,2661,42.4652,0.36687826,138,132,,0,O97594,Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Chondroitin sulfate proteoglycan 6),Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Chondroitin sulfate proteoglycan 6),GO:0005524; GO:0006281; GO:0051301; GO:0000785; GO:0051276; GO:0000775; GO:0005737; GO:0045502; GO:0007126; GO:0030893; GO:0007067; GO:0007052; GO:0016363; GO:0006275; GO:0007165; GO:0000922,"ATP binding; DNA repair; cell division; chromatin; chromosome organization; chromosome, centromeric region; cytoplasm; dynein binding; meiosis; meiotic cohesin complex; mitosis; mitotic spindle organization; nuclear matrix; regulation of DNA replication; signal transduction; spindle pole",PF06470;PF02463;,,,,,,,,,SMC3_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic nuclear division [GO:0007126]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle organization [GO:0007052]; regulation of DNA replication [GO:0006275]; signal transduction [GO:0007165] comp143512_c0_seq1,2874,39.0049,0.33910007,309,828,,4.00E-101,Q5PQS6,Protein SMG9 (Protein smg-9 homolog),Protein SMG9 (Protein smg-9 homolog),GO:0005622; GO:0000184,"intracellular; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",PF10220;,1.00E-26,CHOYP_SMG9.1.1,,,,,,,SMG9_RAT,Rattus norvegicus (Rat),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" comp143513_c0_seq1,2059,29.966,0.33398192,689,3088,,,,,,,,,,,2.00E-15,ruditapes_c17707,,,,,,, comp143514_c0_seq1,2428,32.3723,0.39317447,21,73,,,,,,,,,5.00E-12,CHOYP_contig_017664,,,,,,,,, comp143514_c0_seq3,2431,32.3735,0.39266346,0,0,,,,,,,,,5.00E-12,CHOYP_contig_050156,,,,,,,,, comp143514_c0_seq4,1266,33.6493,0.30752446,2,24,,,,,,,,,3.00E-12,CHOYP_contig_050156,,,,,,,,, comp143515_c0_seq1,2841,37.0996,0.38732472,19,0,,7.00E-108,Q7ZV84,"Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)","Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)",GO:0035085; GO:0060271; GO:0045502; GO:0044458,cilium axoneme; cilium morphogenesis; dynein binding; motile cilium assembly,,,,,,,,,,DAAF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cell migration involved in heart jogging [GO:0003305]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; gastrulation [GO:0007369]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart rudiment morphogenesis [GO:0003314]; motile cilium assembly [GO:0044458]; pronephros development [GO:0048793] comp143515_c0_seq3,2783,37.1542,0.3941231,0,0,,8.00E-108,Q7ZV84,"Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)","Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)",GO:0035085; GO:0060271; GO:0045502; GO:0044458,cilium axoneme; cilium morphogenesis; dynein binding; motile cilium assembly,,2.00E-43,CHOYP_LOC100672555.1.1,,,,,,,DAAF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axoneme assembly [GO:0035082]; cell migration involved in heart jogging [GO:0003305]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; gastrulation [GO:0007369]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart rudiment morphogenesis [GO:0003314]; motile cilium assembly [GO:0044458]; pronephros development [GO:0048793] comp143516_c3_seq1,2342,33.2622,0.57428764,170,647,,3.00E-42,A1A4P5,Prefoldin subunit 2,Prefoldin subunit 2,GO:0051086; GO:0005829; GO:0005739; GO:0005634; GO:0016272,chaperone mediated protein folding independent of cofactor; cytosol; mitochondrion; nucleus; prefoldin complex,PF01920;,,,,,,,,,PFD2_BOVIN,Bos taurus (Bovine),chaperone mediated protein folding independent of cofactor [GO:0051086]; protein folding [GO:0006457] comp143516_c3_seq2,2297,33.3914,0.56562297,88,507,,3.00E-42,A1A4P5,Prefoldin subunit 2,Prefoldin subunit 2,GO:0051086; GO:0005829; GO:0005739; GO:0005634; GO:0016272,chaperone mediated protein folding independent of cofactor; cytosol; mitochondrion; nucleus; prefoldin complex,PF01920;,1.00E-45,CHOYP_LOC589720.1.1,1.00E-86,ruditapes2_c315,,,,,PFD2_BOVIN,Bos taurus (Bovine),chaperone mediated protein folding independent of cofactor [GO:0051086]; protein folding [GO:0006457] comp143517_c2_seq1,5725,43.441,0.44044052,0,0,,1.00E-123,Q8NDM7,WD repeat-containing protein 96,Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96),,,,0,CHOYP_LOC100377024.2.2,,,,,,,WDR96_HUMAN,Homo sapiens (Human), comp143517_c2_seq3,5773,43.2877,0.43999781,0,0,,7.00E-124,Q8NDM7,WD repeat-containing protein 96,Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96),,,,0,CHOYP_LOC100377024.1.2,,,,,,,WDR96_HUMAN,Homo sapiens (Human), comp143517_c2_seq4,5677,43.5441,0.44678835,0,0,,1.00E-08,Q96MT7,WD repeat-containing protein 52,Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52),,,PF00400;,,,,,,,,,WDR52_HUMAN,Homo sapiens (Human), comp143517_c2_seq5,5629,43.7023,0.44721978,0,0,,1.00E-123,Q8NDM7,WD repeat-containing protein 96,Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96),,,,0,CHOYP_LOC100377024.2.2,,,,,,,WDR96_HUMAN,Homo sapiens (Human), comp143517_c2_seq6,5450,44.422,0.44752126,0,0,,1.00E-08,Q96MT7,WD repeat-containing protein 52,Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52),,,PF00400;,,,,,,,,,WDR52_HUMAN,Homo sapiens (Human), comp143517_c2_seq7,5402,44.5946,0.44788363,0,0,,1.00E-123,Q8NDM7,WD repeat-containing protein 96,Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96),,,,0,CHOYP_LOC100377024.2.2,,,,,,,WDR96_HUMAN,Homo sapiens (Human), comp143518_c1_seq3,1420,42.0423,0.57892009,11,150,,2.00E-137,Q8R3P7,Clusterin-associated protein 1,Clusterin-associated protein 1,GO:0030030; GO:0005929; GO:0005634,cell projection organization; cilium; nucleus,PF10234;,3.00E-152,CHOYP_BRAFLDRAFT_119036.1.1,,,4.00E-82,AM863560.p.cg.6,7,,CLUA1_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; floor plate formation [GO:0021508]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; left/right pattern formation [GO:0060972]; neural tube closure [GO:0001843]; smoothened signaling pathway [GO:0007224] comp143518_c2_seq1,1899,33.1227,0.95793746,0,0,,1.00E-08,Q09139,"Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7)","Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7)",GO:0042995; GO:0021846; GO:0005737; GO:0008289; GO:0022008; GO:0043025; GO:0060134; GO:0005215,cell projection; cell proliferation in forebrain; cytoplasm; lipid binding; neurogenesis; neuronal cell body; prepulse inhibition; transporter activity,PF00061;,,,,,,,,,FABP7_BOVIN,Bos taurus (Bovine),cell proliferation in forebrain [GO:0021846]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134] comp143518_c2_seq6,1389,35.1332,0.93080405,0,0,,8.00E-09,Q09139,"Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7)","Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7)",GO:0042995; GO:0021846; GO:0005737; GO:0008289; GO:0022008; GO:0043025; GO:0060134; GO:0005215,cell projection; cell proliferation in forebrain; cytoplasm; lipid binding; neurogenesis; neuronal cell body; prepulse inhibition; transporter activity,PF00061;,,,2.00E-56,ruditapes_c9025,,,,,FABP7_BOVIN,Bos taurus (Bovine),cell proliferation in forebrain [GO:0021846]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134] comp143519_c0_seq1,2534,41.8311,0.36113818,1,0,,0,O15457,MutS protein homolog 4 (hMSH4),MutS protein homolog 4 (hMSH4),GO:0005524; GO:0008094; GO:0051026; GO:0007292; GO:0045143; GO:0006298; GO:0030983; GO:0001541; GO:0007131; GO:0007283; GO:0000795,ATP binding; DNA-dependent ATPase activity; chiasma assembly; female gamete generation; homologous chromosome segregation; mismatch repair; mismatched DNA binding; ovarian follicle development; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex,PF05188;PF05192;PF05190;PF00488;,4.00E-109,CHOYP_MSH4.1.1,,,,,,,MSH4_HUMAN,Homo sapiens (Human),female gamete generation [GO:0007292]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp143519_c0_seq10,558,37.8136,0.40223191,10,0,,2.00E-27,O74773,DNA mismatch repair protein msh2,DNA mismatch repair protein msh2,GO:0005524; GO:0016887; GO:0032301; GO:0032302; GO:0000403; GO:0005829; GO:0000406; GO:0000400; GO:0007534; GO:0043570; GO:0006298; GO:0030983; GO:0000228,ATP binding; ATPase activity; MutSalpha complex; MutSbeta complex; Y-form DNA binding; cytosol; double-strand/single-strand DNA junction binding; four-way junction DNA binding; gene conversion at mating-type locus; maintenance of DNA repeat elements; mismatch repair; mismatched DNA binding; nuclear chromosome,PF01624;PF05188;PF05192;PF05190;PF00488;,,,,,,,,,MSH2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),gene conversion at mating-type locus [GO:0007534]; maintenance of DNA repeat elements [GO:0043570]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of reciprocal meiotic recombination [GO:0045128]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; removal of nonhomologous ends [GO:0000735] comp143519_c0_seq12,848,41.6274,0.43614008,0,0,,3.00E-121,O15457,MutS protein homolog 4 (hMSH4),MutS protein homolog 4 (hMSH4),GO:0005524; GO:0008094; GO:0051026; GO:0007292; GO:0045143; GO:0006298; GO:0030983; GO:0001541; GO:0007131; GO:0007283; GO:0000795,ATP binding; DNA-dependent ATPase activity; chiasma assembly; female gamete generation; homologous chromosome segregation; mismatch repair; mismatched DNA binding; ovarian follicle development; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex,PF05188;PF05192;PF05190;PF00488;,,,,,,,,,MSH4_HUMAN,Homo sapiens (Human),female gamete generation [GO:0007292]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp143519_c0_seq4,3107,40.618,0.36720969,124,9,,0,O15457,MutS protein homolog 4 (hMSH4),MutS protein homolog 4 (hMSH4),GO:0005524; GO:0008094; GO:0051026; GO:0007292; GO:0045143; GO:0006298; GO:0030983; GO:0001541; GO:0007131; GO:0007283; GO:0000795,ATP binding; DNA-dependent ATPase activity; chiasma assembly; female gamete generation; homologous chromosome segregation; mismatch repair; mismatched DNA binding; ovarian follicle development; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex,PF05188;PF05192;PF05190;PF00488;,,,,,,,,,MSH4_HUMAN,Homo sapiens (Human),female gamete generation [GO:0007292]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp143519_c0_seq6,1633,42.0698,0.31852944,17,0,,,,,,,,,7.00E-78,CHOYP_MSH4.1.1,,,,,,,,, comp143522_c0_seq1,2003,34.4483,0.40904578,0,0,,8.00E-16,Q8N5N7,"39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)","39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF10501;,,,,,,,,,RM50_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126] comp143522_c0_seq3,1793,35.304,0.41715882,0,0,,7.00E-16,Q8N5N7,"39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)","39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)",GO:0005739; GO:0005840,mitochondrion; ribosome,PF10501;,,,,,,,,,RM50_HUMAN,Homo sapiens (Human),mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126] comp143525_c2_seq4,1825,37.589,0.32607153,3,44,,4.00E-21,Q8VE62,Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1),Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1),GO:0003723; GO:0005737; GO:0008494,RNA binding; cytoplasm; translation activator activity,PF02854;PF07145;,,,,,,,,,PAIP1_MOUSE,Mus musculus (Mouse), comp143525_c2_seq6,1837,37.5068,0.32542503,8,16,,4.00E-21,Q8VE62,Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1),Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1),GO:0003723; GO:0005737; GO:0008494,RNA binding; cytoplasm; translation activator activity,PF02854;PF07145;,,,,,,,,,PAIP1_MOUSE,Mus musculus (Mouse), comp143527_c0_seq8,954,41.4046,0.80799494,5,3,,2.00E-85,P24008,3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1),3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1),GO:0003865; GO:0070402; GO:0033218; GO:0006702; GO:0060348; GO:0070852; GO:0030154; GO:0071320; GO:0071549; GO:0071872; GO:0071392; GO:0071363; GO:0032869; GO:0009267; GO:0071394; GO:0021987; GO:0047751; GO:0042747; GO:0016101; GO:0005789; GO:0030540; GO:0021766; GO:0021854; GO:0016021; GO:0043231; GO:0001889; GO:0030539; GO:0008584; GO:0043209; GO:0043025; GO:0048471; GO:0021983; GO:0042448; GO:0042493; GO:0032354; GO:0060992; GO:0060416; GO:0014850; GO:0042428; GO:0021510; GO:0021794; GO:0001655,"3-oxo-5-alpha-steroid 4-dehydrogenase activity; NADPH binding; amide binding; androgen biosynthetic process; bone development; cell body fiber; cell differentiation; cellular response to cAMP; cellular response to dexamethasone stimulus; cellular response to epinephrine stimulus; cellular response to estradiol stimulus; cellular response to growth factor stimulus; cellular response to insulin stimulus; cellular response to starvation; cellular response to testosterone stimulus; cerebral cortex development; cholestenone 5-alpha-reductase activity; circadian sleep/wake cycle, REM sleep; diterpenoid metabolic process; endoplasmic reticulum membrane; female genitalia development; hippocampus development; hypothalamus development; integral to membrane; intracellular membrane-bounded organelle; liver development; male genitalia development; male gonad development; myelin sheath; neuronal cell body; perinuclear region of cytoplasm; pituitary gland development; progesterone metabolic process; response to drug; response to follicle-stimulating hormone stimulus; response to fungicide; response to growth hormone stimulus; response to muscle activity; serotonin metabolic process; spinal cord development; thalamus development; urogenital system development",PF02544;,2.00E-12,CHOYP_SRD5A1.1.1,,,,,,,S5A1_RAT,Rattus norvegicus (Rat),"androgen biosynthetic process [GO:0006702]; androgen metabolic process [GO:0008209]; bone development [GO:0060348]; cell differentiation [GO:0030154]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to estradiol stimulus [GO:0071392]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; cerebral cortex development [GO:0021987]; circadian sleep/wake cycle, REM sleep [GO:0042747]; diterpenoid metabolic process [GO:0016101]; female genitalia development [GO:0030540]; hippocampus development [GO:0021766]; hypothalamus development [GO:0021854]; liver development [GO:0001889]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; male sex differentiation [GO:0046661]; pituitary gland development [GO:0021983]; progesterone metabolic process [GO:0042448]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to follicle-stimulating hormone [GO:0032354]; response to fungicide [GO:0060992]; response to growth hormone [GO:0060416]; response to muscle activity [GO:0014850]; response to organic cyclic compound [GO:0014070]; response to testosterone [GO:0033574]; serotonin metabolic process [GO:0042428]; spinal cord development [GO:0021510]; steroid biosynthetic process [GO:0006694]; thalamus development [GO:0021794]; urogenital system development [GO:0001655]" comp143529_c0_seq1,1778,37.739,0.35422221,725,4149,,2.00E-132,Q58DG1,"UPF0160 protein MYG1, mitochondrial","UPF0160 protein MYG1, mitochondrial",GO:0005739; GO:0005634,mitochondrion; nucleus,PF03690;,1.00E-69,CHOYP_LOC100698240.4.4,,,,,,,MYG1_BOVIN,Bos taurus (Bovine),locomotory exploration behavior [GO:0035641] comp143530_c1_seq1,1945,44.5244,0.47716883,0,33,,1.00E-06,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp143530_c1_seq2,3725,44.1342,0.47149464,119,40,,3.00E-37,Q14596,Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B),Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B),GO:0031430; GO:0005776; GO:0031410; GO:0005829; GO:0005770; GO:0005764; GO:0016236; GO:0051019; GO:0045668; GO:0000407; GO:0051259; GO:0030500; GO:0032872; GO:0043130; GO:0008270,M band; autophagic vacuole; cytoplasmic vesicle; cytosol; late endosome; lysosome; macroautophagy; mitogen-activated protein kinase binding; negative regulation of osteoblast differentiation; pre-autophagosomal structure; protein oligomerization; regulation of bone mineralization; regulation of stress-activated MAPK cascade; ubiquitin binding; zinc ion binding,PF16158;PF00564;PF00569;,,,,,,,,,NBR1_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; protein oligomerization [GO:0051259]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872] comp143530_c1_seq5,2951,45.7133,0.43900495,12,0,,1.00E-37,Q14596,Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B),Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B),GO:0031430; GO:0005776; GO:0031410; GO:0005829; GO:0005770; GO:0005764; GO:0016236; GO:0051019; GO:0045668; GO:0000407; GO:0051259; GO:0030500; GO:0032872; GO:0043130; GO:0008270,M band; autophagic vacuole; cytoplasmic vesicle; cytosol; late endosome; lysosome; macroautophagy; mitogen-activated protein kinase binding; negative regulation of osteoblast differentiation; pre-autophagosomal structure; protein oligomerization; regulation of bone mineralization; regulation of stress-activated MAPK cascade; ubiquitin binding; zinc ion binding,PF16158;PF00564;PF00569;,,,,,,,,,NBR1_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; protein oligomerization [GO:0051259]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872] comp143531_c1_seq1,3227,42.4233,0.48316125,8,16,,1.00E-145,Q6DFC6,WD repeat-containing protein 75,WD repeat-containing protein 75,GO:0005730,nucleolus,PF00400;,,,,,,,,,WDR75_XENLA,Xenopus laevis (African clawed frog), comp143531_c1_seq2,2990,42.7759,0.47608733,38,226,,2.00E-145,Q6DFC6,WD repeat-containing protein 75,WD repeat-containing protein 75,GO:0005730,nucleolus,PF00400;,,,2.00E-16,ruditapes2_c414,,,,,WDR75_XENLA,Xenopus laevis (African clawed frog), comp143534_c1_seq1,603,45.7711,0.45260522,3,5,,8.00E-13,Q13823,Nucleolar GTP-binding protein 2 (Autoantigen NGP-1),Nucleolar GTP-binding protein 2 (Autoantigen NGP-1),GO:0005525; GO:0003924; GO:0005730; GO:0042254,GTP binding; GTPase activity; nucleolus; ribosome biogenesis,PF01926;PF08153;,1.00E-43,CHOYP_GNL1.1.1,,,,,,,NOG2_HUMAN,Homo sapiens (Human),ribosome biogenesis [GO:0042254] comp143534_c1_seq2,2288,41.7395,0.52390478,94,230,,1.00E-158,Q7YR35,Guanine nucleotide-binding protein-like 1,Guanine nucleotide-binding protein-like 1,GO:0005525; GO:0003924; GO:0005829; GO:0006974; GO:0042254,GTP binding; GTPase activity; cytosol; response to DNA damage stimulus; ribosome biogenesis,PF01926;,,,,,,,,,GNL1_PANTR,Pan troglodytes (Chimpanzee),cellular response to DNA damage stimulus [GO:0006974]; ribosome biogenesis [GO:0042254] comp143534_c1_seq3,1483,43.1558,0.552863,0,7,,2.00E-13,Q9BVP2,Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin),Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin),GO:0005525; GO:0003924; GO:0008283; GO:0005730; GO:0005654; GO:0042127; GO:0042254,GTP binding; GTPase activity; cell proliferation; nucleolus; nucleoplasm; regulation of cell proliferation; ribosome biogenesis,PF08701;PF01926;,,,,,,,,,GNL3_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of telomere maintenance [GO:0032206]; regulation of cell proliferation [GO:0042127]; ribosome biogenesis [GO:0042254]" comp143534_c1_seq4,519,40.8478,0.42503109,0,0,,7.00E-11,Q21086,Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1),Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1),GO:0005525; GO:0003924; GO:0007281; GO:0002119; GO:0005730; GO:0005654; GO:0042127; GO:0040014; GO:0042254,GTP binding; GTPase activity; germ cell development; nematode larval development; nucleolus; nucleoplasm; regulation of cell proliferation; regulation of multicellular organism growth; ribosome biogenesis,PF08701;PF01926;,3.00E-32,CHOYP_GNL1.1.1,,,,,,,GNL3_CAEEL,Caenorhabditis elegans,germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014]; ribosome biogenesis [GO:0042254] comp143535_c0_seq11,531,32.7684,0.44284286,0,3,,6.00E-30,Q5SXM8,DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein),DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein),GO:0005739; GO:0008270,mitochondrion; zinc ion binding,PF05180;,4.00E-11,CHOYP_DGRI_GH24435.1.1,,,,,,,DNLZ_HUMAN,Homo sapiens (Human),protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150]; protein stabilization [GO:0050821] comp143535_c0_seq5,1377,33.2607,0.37886901,3,11,,5.00E-28,Q5SXM8,DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein),DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein),GO:0005739; GO:0008270,mitochondrion; zinc ion binding,PF05180;,,,3.00E-28,ruditapes_c7271,,,,,DNLZ_HUMAN,Homo sapiens (Human),protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150]; protein stabilization [GO:0050821] comp143537_c0_seq1,303,44.2244,0.41379761,4,4,,2.00E-30,Q32LT9,Probable carboxypeptidase PM20D1.1 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1.1),Probable carboxypeptidase PM20D1.1 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1.1),GO:0005576; GO:0046872; GO:0008233; GO:0006508,extracellular region; metal ion binding; peptidase activity; proteolysis,PF07687;PF01546;,,,,,,,,,P2011_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),peptide catabolic process [GO:0043171] comp143537_c1_seq1,5739,43.6313,0.53305681,471,5019,,0,Q5BJL5,Protein strawberry notch homolog 1,Protein strawberry notch homolog 1,GO:0006355,"regulation of transcription, DNA-dependent",PF13871;,0,CHOYP_SBNO1.1.1,,,,,,,SBNO1_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]" comp143538_c0_seq1,2282,33.1727,0.56815997,37,78,,2.00E-76,Q80U58,Pumilio homolog 2,Pumilio homolog 2,GO:0003723; GO:0010494; GO:0048471; GO:0006417; GO:0034063,RNA binding; cytoplasmic stress granule; perinuclear region of cytoplasm; regulation of translation; stress granule assembly,PF00806;,,,,,,,,,PUM2_MOUSE,Mus musculus (Mouse),positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063] comp143538_c0_seq3,1736,50.288,0.48340718,210,249,,8.00E-121,Q8TB72,Pumilio homolog 2 (Pumilio-2),Pumilio homolog 2 (Pumilio-2),GO:0003723; GO:0010494; GO:0048471; GO:0006417; GO:0034063,RNA binding; cytoplasmic stress granule; perinuclear region of cytoplasm; regulation of translation; stress granule assembly,PF00806;,,,,,,,,,PUM2_HUMAN,Homo sapiens (Human),positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063] comp143538_c0_seq5,981,47.4006,0.6413038,5,0,,6.00E-83,Q9ZW02,Pumilio homolog 3 (APUM-3) (AtPUM3),Pumilio homolog 3 (APUM-3) (AtPUM3),GO:0005737; GO:0003729; GO:0005886; GO:0006417,cytoplasm; mRNA binding; plasma membrane; regulation of translation,PF07990;PF00806;,3.00E-112,CHOYP_PUM1.1.1,,,,,,,PUM3_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of translation [GO:0006417] comp143540_c0_seq1,2330,42.8755,0.48011786,44,87,,0,Q6INU8,Tetratricopeptide repeat protein 30A (TPR repeat protein 30A),Tetratricopeptide repeat protein 30A (TPR repeat protein 30A),GO:0005879; GO:0005929; GO:0042073; GO:0018095; GO:0005215,axonemal microtubule; cilium; intraflagellar transport; protein polyglutamylation; transporter activity,PF13174;,0,CHOYP_TT30A.1.1,,,,,,,TT30A_XENLA,Xenopus laevis (African clawed frog),intraciliary transport [GO:0042073]; protein polyglutamylation [GO:0018095] comp143541_c0_seq1,4196,40.062,0.38027788,40,58,,,,,,,,,1.00E-21,CHOYP_HMMR.1.1,,,,,,,,, comp143541_c0_seq2,4153,40.1156,0.37715858,24,74,,3.00E-14,P97779,Hyaluronan-mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168),Hyaluronan-mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168),GO:0009986; GO:0007267; GO:0005737; GO:0007010; GO:0005540,cell surface; cell-cell signaling; cytoplasm; cytoskeleton organization; hyaluronic acid binding,PF15908;PF15905;,,,,,,,,,HMMR_RAT,Rattus norvegicus (Rat),cell-cell signaling [GO:0007267]; cytoskeleton organization [GO:0007010] comp143544_c2_seq1,1473,45.2138,0.49439345,53,411,,5.00E-143,O76463,"Nitrilase and fragile histidine triad fusion protein NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase); Nitrilase homolog (EC 3.5.-.-)]","Nitrilase and fragile histidine triad fusion protein NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase); Nitrilase homolog (EC 3.5.-.-)]",GO:0047710; GO:0016810; GO:0006139; GO:0000166,"bis(5'-adenosyl)-triphosphatase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; nucleobase-containing compound metabolic process; nucleotide binding",PF00795;PF01230;,7.00E-27,CHOYP_PHUM_PHUM328150.1.1,,,,,,,NFT1_CAEEL,Caenorhabditis elegans,nucleobase-containing compound metabolic process [GO:0006139] comp143544_c2_seq2,407,49.8771,0.55748921,0,0,,2.00E-34,Q86X76,Nitrilase homolog 1 (EC 3.5.-.-),Nitrilase homolog 1 (EC 3.5.-.-),GO:0005739; GO:0000257; GO:0006807,mitochondrion; nitrilase activity; nitrogen compound metabolic process,PF00795;,,,,,,,,,NIT1_HUMAN,Homo sapiens (Human),nitrogen compound metabolic process [GO:0006807] comp143545_c0_seq2,3043,37.3973,1.05595918,3,13,,3.00E-138,Q3ZBY7,Sphingolipid delta(4)-desaturase DES1 (EC 1.14.-.-) (Degenerative spermatocyte homolog 1),Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1),GO:0005789; GO:0006633; GO:0016021; GO:0005739; GO:0016705,"endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; mitochondrion; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00487;PF08557;,2.00E-56,CHOYP_LOC100378209.1.2,,,,,,,DEGS1_BOVIN,Bos taurus (Bovine),ceramide biosynthetic process [GO:0046513]; fatty acid biosynthetic process [GO:0006633] comp143546_c0_seq1,3180,41.4151,0.54328384,38,2,,8.00E-161,Q9D5S7,Leucine-rich repeat and guanylate kinase domain-containing protein,Leucine-rich repeat and guanylate kinase domain-containing protein,GO:0005524; GO:0016301,ATP binding; kinase activity,PF00625;,0,CHOYP_LOC100375230.1.1,,,,,,,LRGUK_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] comp143546_c0_seq2,3342,40.7241,0.55602578,87,0,,3.00E-160,Q9D5S7,Leucine-rich repeat and guanylate kinase domain-containing protein,Leucine-rich repeat and guanylate kinase domain-containing protein,GO:0005524; GO:0016301,ATP binding; kinase activity,PF00625;,0,CHOYP_LOC100375230.1.1,1.00E-38,ruditapes_c7438,,,,,LRGUK_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] comp143548_c0_seq1,2627,39.2844,0.43807971,553,3828,,0,Q96D46,60S ribosomal export protein NMD3 (hNMD3),60S ribosomal export protein NMD3 (hNMD3),GO:0005737; GO:0005730; GO:0005654; GO:0015031,cytoplasm; nucleolus; nucleoplasm; protein transport,PF04981;,0,CHOYP_LOC100373569.1.1,,,,,,,NMD3_HUMAN,Homo sapiens (Human),protein transport [GO:0015031]; ribosomal large subunit export from nucleus [GO:0000055] comp143549_c0_seq2,1945,40.7712,0.486641,50,65,,5.00E-80,Q921W4,Quinone oxidoreductase-like protein 1 (EC 1.-.-.-) (Quinone oxidoreductase homolog 1) (QOH-1) (Zeta-crystallin homolog),Quinone oxidoreductase-like protein 1 (EC 1.-.-.-) (Quinone oxidoreductase homolog 1) (QOH-1) (Zeta-crystallin homolog),GO:0005829; GO:0016491; GO:0008270,cytosol; oxidoreductase activity; zinc ion binding,PF08240;,,,,,,,,,QORL1_MOUSE,Mus musculus (Mouse), comp143549_c0_seq3,1931,41.015,0.49691371,12,108,,1.00E-14,Q28452,Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin),Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin),GO:0070402; GO:0003960; GO:0005829; GO:0003730; GO:0042178; GO:0008270,NADPH binding; NADPH:quinone reductase activity; cytosol; mRNA 3'-UTR binding; xenobiotic catabolic process; zinc ion binding,PF08240;PF00107;,6.00E-61,CHOYP_NEMVEDRAFT_V1G168923.1.1,,,,,,,QOR_LAMGU,Lama guanicoe (Guanaco),xenobiotic catabolic process [GO:0042178] comp143550_c0_seq1,2059,40.068,0.51819566,898,162,,1.00E-11,Q5T5N4,Uncharacterized protein C6orf118,Uncharacterized protein C6orf118,,,PF15739;,9.00E-46,CHOYP_BRAFLDRAFT_76659.1.1,,,,,,,CF118_HUMAN,Homo sapiens (Human), comp143550_c1_seq1,1235,44.1296,0.42106151,79,288,,9.00E-163,Q91821,Maternal embryonic leucine zipper kinase (MELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase),Maternal embryonic leucine zipper kinase (MELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase),GO:0005524; GO:0006915; GO:0005509; GO:0005938; GO:0007049; GO:0030097; GO:0008289; GO:0061351; GO:0004715; GO:0005886; GO:0043065; GO:0046777; GO:0004674,ATP binding; apoptotic process; calcium ion binding; cell cortex; cell cycle; hemopoiesis; lipid binding; neural precursor cell proliferation; non-membrane spanning protein tyrosine kinase activity; plasma membrane; positive regulation of apoptotic process; protein autophosphorylation; protein serine/threonine kinase activity,PF02149;PF00069;,2.00E-165,CHOYP_MELK.1.1,,,,,,,MELK_XENLA,Xenopus laevis (African clawed frog),apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell proliferation [GO:0008283]; hemopoiesis [GO:0030097]; neural precursor cell proliferation [GO:0061351]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777] comp143550_c1_seq5,1590,37.2956,0.54327557,0,0,,,,,,,,,4.00E-62,CHOYP_MELK.1.1,,,,,,,,, comp143552_c1_seq1,1972,40.3651,0.47350018,3,16,,2.00E-51,Q9NPJ1,McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet-Biedl syndrome 6 protein),McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet-Biedl syndrome 6 protein),GO:0005524; GO:0014824; GO:0048854; GO:0005813; GO:0021987; GO:0051131; GO:0042384; GO:0060027; GO:0005829; GO:0050910; GO:0045444; GO:0008406; GO:0001947; GO:0021766; GO:0046907; GO:0032402; GO:0031514; GO:0038108; GO:0045776; GO:0010629; GO:0035058; GO:0045494; GO:0051877; GO:0040018; GO:0006457; GO:0060296; GO:0007608; GO:0035176; GO:0007286; GO:0021756; GO:0051082; GO:0042311; GO:0007601,ATP binding; artery smooth muscle contraction; brain morphogenesis; centrosome; cerebral cortex development; chaperone-mediated protein complex assembly; cilium assembly; convergent extension involved in gastrulation; cytosol; detection of mechanical stimulus involved in sensory perception of sound; fat cell differentiation; gonad development; heart looping; hippocampus development; intracellular transport; melanosome transport; motile cilium; negative regulation of appetite by leptin-mediated signaling pathway; negative regulation of blood pressure; negative regulation of gene expression; nonmotile primary cilium assembly; photoreceptor cell maintenance; pigment granule aggregation in cell center; positive regulation of multicellular organism growth; protein folding; regulation of cilium beat frequency involved in ciliary motility; sensory perception of smell; social behavior; spermatid development; striatum development; unfolded protein binding; vasodilation; visual perception,PF00118;,,,,,,,,,MKKS_HUMAN,Homo sapiens (Human),artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; chaperone-mediated protein complex assembly [GO:0051131]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; determination of left/right symmetry [GO:0007368]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; gonad development [GO:0008406]; heart development [GO:0007507]; heart looping [GO:0001947]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; melanosome transport [GO:0032402]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; pigment granule aggregation in cell center [GO:0051877]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of stress fiber assembly [GO:0051492]; sensory perception of smell [GO:0007608]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; vasodilation [GO:0042311]; visual perception [GO:0007601] comp143553_c1_seq2,3329,41.3938,0.45432069,36,98,,2.00E-119,Q0JMY1,Poly [ADP-ribose] polymerase 2-B (PARP-2-B) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 2-B) (ADPRT-2-B) (Poly[ADP-ribose] synthase 2-B),Poly [ADP-ribose] polymerase 2-B (PARP-2-B) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 2-B) (ADPRT-2-B) (Poly[ADP-ribose] synthase 2-B),GO:0003950; GO:0005634; GO:0006471,NAD+ ADP-ribosyltransferase activity; nucleus; protein ADP-ribosylation,PF00644;PF02877;PF05406;,2.00E-158,CHOYP_LOC100495846.1.1,,,,,,,PRP2B_ORYSJ,Oryza sativa subsp. japonica (Rice),DNA ligation involved in DNA repair [GO:0051103]; lagging strand elongation [GO:0006273]; protein ADP-ribosylation [GO:0006471] comp143553_c1_seq3,3406,41.2801,0.47508863,69,103,,0,O88554,Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2),Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2),GO:0003677; GO:0003950; GO:0006284; GO:0097191; GO:0005730; GO:0005654; GO:0006471,DNA binding; NAD+ ADP-ribosyltransferase activity; base-excision repair; extrinsic apoptotic signaling pathway; nucleolus; nucleoplasm; protein ADP-ribosylation,PF00644;PF02877;PF05406;,,,,,,,,,PARP2_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; extrinsic apoptotic signaling pathway [GO:0097191]; lagging strand elongation [GO:0006273]; protein ADP-ribosylation [GO:0006471] comp143554_c0_seq1,5236,45.4354,0.50778809,0,0,,,,,,,,,2.00E-104,CHOYP_LOC100376246.1.1,,,,,,,,, comp143554_c0_seq10,5179,45.3756,0.50346382,0,0,,,,,,,,,7.00E-103,CHOYP_LOC100376246.1.1,,,,,,,,, comp143554_c0_seq5,5167,45.4616,0.51410043,0,0,,,,,,,,,2.00E-104,CHOYP_LOC100376246.1.1,,,,,,,,, comp143554_c0_seq6,5213,45.4633,0.51314508,0,3,,,,,,,,,2.00E-104,CHOYP_LOC100376246.1.1,,,,,,,,, comp143554_c0_seq9,5224,45.4058,0.49841717,0,0,,,,,,,,,7.00E-103,CHOYP_LOC100376246.1.1,,,,,,,,, comp143555_c0_seq1,2541,37.9378,0.71497508,0,0,,9.00E-52,Q9D3W5,Leucine-rich repeat-containing protein 71,Leucine-rich repeat-containing protein 71,,,PF13516;,,,,,,,,,LRC71_MOUSE,Mus musculus (Mouse), comp143555_c0_seq3,1697,35.0619,0.73531649,0,0,,,,,,,,,6.00E-41,CHOYP_LOC100367394.1.2,,,,,,,,, comp143555_c0_seq4,2527,37.9106,0.70894252,6,0,,2.00E-50,Q8N4P6,Leucine-rich repeat-containing protein 71,Leucine-rich repeat-containing protein 71,,,PF13516;,6.00E-62,CHOYP_LOC100367394.1.2,,,,,,,LRC71_HUMAN,Homo sapiens (Human), comp143555_c0_seq8,2563,38.1584,0.66927987,0,0,,1.00E-51,Q9D3W5,Leucine-rich repeat-containing protein 71,Leucine-rich repeat-containing protein 71,,,PF13516;,,,,,,,,,LRC71_MOUSE,Mus musculus (Mouse), comp143556_c0_seq1,4053,42.5611,0.48619596,357,148,,0,Q28C33,TBC1 domain family member 30,TBC1 domain family member 30,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF15733;PF00566;,1.00E-137,CHOYP_BRAFLDRAFT_70346.1.1,,,,,,,TBC30_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of cilium assembly [GO:1902017]; regulation of vesicle fusion [GO:0031338] comp143556_c0_seq3,1399,42.8878,0.28011219,0,0,,1.00E-06,Q28C33,TBC1 domain family member 30,TBC1 domain family member 30,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF15733;PF00566;,,,,,,,,,TBC30_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of cilium assembly [GO:1902017]; regulation of vesicle fusion [GO:0031338] comp143557_c0_seq11,209,29.1866,1.60134385,7,12,,,,,,,,,,,4.00E-11,ruditapes_c30227,,,,,,, comp143558_c1_seq1,4341,38.6777,0.56138843,31,9,,0,Q32TF8,EF-hand domain-containing family member C2,EF-hand domain-containing family member C2,GO:0005509,calcium ion binding,PF06565;,,,,,,,,,EFHC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143558_c1_seq2,3030,41.9142,0.57969952,42,9,,,,,,,,,0,CHOYP_LOC100377378.1.1,,,,,,,,, comp143558_c1_seq3,4177,38.6881,0.56337652,200,24,,2.00E-123,Q9D9T8,EF-hand domain-containing protein 1 (Myoclonin-1),EF-hand domain-containing protein 1 (Myoclonin-1),GO:0005930; GO:0005509; GO:0006874; GO:0005929; GO:0043025; GO:0043065,axoneme; calcium ion binding; cellular calcium ion homeostasis; cilium; neuronal cell body; positive regulation of apoptotic process,PF06565;,0,CHOYP_LOC100377378.1.1,,,,,,,EFHC1_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874]; cerebral cortex cell migration [GO:0021795]; positive regulation of apoptotic process [GO:0043065] comp143558_c1_seq4,4163,38.7941,0.56219855,0,0,,0,Q32TF8,EF-hand domain-containing family member C2,EF-hand domain-containing family member C2,GO:0005509,calcium ion binding,PF06565;,,,,,,,,,EFHC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143558_c1_seq7,3015,42.0232,0.57960633,43,9,,3.00E-126,Q9D9T8,EF-hand domain-containing protein 1 (Myoclonin-1),EF-hand domain-containing protein 1 (Myoclonin-1),GO:0005930; GO:0005509; GO:0006874; GO:0005929; GO:0043025; GO:0043065,axoneme; calcium ion binding; cellular calcium ion homeostasis; cilium; neuronal cell body; positive regulation of apoptotic process,PF06565;,,,,,,,,,EFHC1_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874]; cerebral cortex cell migration [GO:0021795]; positive regulation of apoptotic process [GO:0043065] comp143558_c1_seq8,4327,38.7566,0.56091562,0,0,,0,Q32TF8,EF-hand domain-containing family member C2,EF-hand domain-containing family member C2,GO:0005509,calcium ion binding,PF06565;,0,CHOYP_LOC100377378.1.1,,,,,,,EFHC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143559_c0_seq1,1128,42.3759,0.41649572,535,871,,1.00E-146,Q5R7X9,Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog),Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog),GO:0008408; GO:0000077; GO:0006281; GO:0071479; GO:0008853; GO:0090305; GO:0005634,3'-5' exonuclease activity; DNA damage checkpoint; DNA repair; cellular response to ionizing radiation; exodeoxyribonuclease III activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF02144;,1.00E-143,CHOYP_LOC100370910.1.1,,,,,,,RAD1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; meiotic recombination checkpoint [GO:0051598]; substantia nigra development [GO:0021762] comp143560_c0_seq1,1848,44.8052,0.51230325,0,0,,5.00E-07,O14089,Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN),Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN),GO:0005525; GO:0005829; GO:0051028; GO:0031965; GO:0005643; GO:0006913; GO:0006605; GO:0008565,GTP binding; cytosol; mRNA transport; nuclear membrane; nuclear pore; nucleocytoplasmic transport; protein targeting; protein transporter activity,,2.00E-155,CHOYP_IPO5.1.1,,,,,,,IMB2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein targeting [GO:0006605]; ribosomal protein import into nucleus [GO:0006610]" comp143560_c0_seq4,3143,44.2571,0.51589998,4,0,,8.00E-16,O60100,Probable importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123),Probable importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123),GO:0005829; GO:0005643; GO:0006913; GO:0006605; GO:0008565,cytosol; nuclear pore; nucleocytoplasmic transport; protein targeting; protein transporter activity,PF03810;,0,CHOYP_IPO5.1.1,,,,,,,IMB4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"NLS-bearing protein import into nucleus [GO:0006607]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein targeting [GO:0006605]; ribosomal protein import into nucleus [GO:0006610]" comp143560_c0_seq5,3568,43.6659,0.53680209,55,128,,0,Q8BKC5,Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5),Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5),GO:0006607; GO:0005737; GO:0005634; GO:0008565; GO:0006610,NLS-bearing protein import into nucleus; cytoplasm; nucleus; protein transporter activity; ribosomal protein import into nucleus,PF02985;,,,2.00E-60,ruditapes_c9588,,,,,IPO5_MOUSE,Mus musculus (Mouse),"cellular response to amino acid stimulus [GO:0071230]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]" comp143560_c0_seq6,1347,45.954,0.46664175,0,0,,2.00E-159,Q8BKC5,Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5),Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5),GO:0006607; GO:0005737; GO:0005634; GO:0008565; GO:0006610,NLS-bearing protein import into nucleus; cytoplasm; nucleus; protein transporter activity; ribosomal protein import into nucleus,PF02985;,,,,,,,,,IPO5_MOUSE,Mus musculus (Mouse),"cellular response to amino acid stimulus [GO:0071230]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]" comp143563_c1_seq1,2965,46.1046,0.47172461,0,0,,0,Q96N67,Dedicator of cytokinesis protein 7,Dedicator of cytokinesis protein 7,GO:0048365; GO:0032863; GO:0030424; GO:0007409; GO:0045178; GO:0045200; GO:0030426; GO:0005085; GO:0000226; GO:0043473; GO:0033138; GO:0007264,Rac GTPase binding; activation of Rac GTPase activity; axon; axonogenesis; basal part of cell; establishment of neuroblast polarity; growth cone; guanyl-nucleotide exchange factor activity; microtubule cytoskeleton organization; pigmentation; positive regulation of peptidyl-serine phosphorylation; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;,0,CHOYP_DOCK7.3.3,,,,,,,DOCK7_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] comp143563_c1_seq2,3202,46.065,0.46167241,0,0,,,,,,,,,0,CHOYP_DOCK7.1.3,,,,,,,,, comp143563_c1_seq3,2965,46.1383,0.45931093,0,0,,0,Q96N67,Dedicator of cytokinesis protein 7,Dedicator of cytokinesis protein 7,GO:0048365; GO:0032863; GO:0030424; GO:0007409; GO:0045178; GO:0045200; GO:0030426; GO:0005085; GO:0000226; GO:0043473; GO:0033138; GO:0007264,Rac GTPase binding; activation of Rac GTPase activity; axon; axonogenesis; basal part of cell; establishment of neuroblast polarity; growth cone; guanyl-nucleotide exchange factor activity; microtubule cytoskeleton organization; pigmentation; positive regulation of peptidyl-serine phosphorylation; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;,0,CHOYP_DOCK7.3.3,,,,,,,DOCK7_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] comp143563_c1_seq5,3202,46.0962,0.47200122,0,0,,,,,,,,,0,CHOYP_DOCK7.1.3,,,,,,,,, comp143564_c1_seq1,1952,42.2131,0.55456488,66,134,,8.00E-152,Q8BX09,Retinoblastoma-binding protein 5 (RBBP-5),Retinoblastoma-binding protein 5 (RBBP-5),GO:0071339; GO:0048188; GO:0042800; GO:0006355; GO:0006974; GO:0043627; GO:0044212; GO:0006351,"MLL1 complex; Set1C/COMPASS complex; histone methyltransferase activity (H3-K4 specific); regulation of transcription, DNA-dependent; response to DNA damage stimulus; response to estrogen stimulus; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00400;,4.00E-177,CHOYP_BRAFLDRAFT_203393.2.2,,,,,,,RBBP5_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]" comp143564_c1_seq3,1329,45.222,0.66259095,6,0,,7.00E-155,Q8BX09,Retinoblastoma-binding protein 5 (RBBP-5),Retinoblastoma-binding protein 5 (RBBP-5),GO:0071339; GO:0048188; GO:0042800; GO:0006355; GO:0006974; GO:0043627; GO:0044212; GO:0006351,"MLL1 complex; Set1C/COMPASS complex; histone methyltransferase activity (H3-K4 specific); regulation of transcription, DNA-dependent; response to DNA damage stimulus; response to estrogen stimulus; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00400;,3.00E-177,CHOYP_BRAFLDRAFT_203393.2.2,,,,,,,RBBP5_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]" comp143565_c1_seq2,1904,35.9769,0.45589756,231,527,,7.00E-15,Q0VFD6,Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1),Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1),GO:0005813; GO:0033566; GO:0008274; GO:0005819,centrosome; gamma-tubulin complex localization; gamma-tubulin ring complex; spindle,PF12554;,,,,,,,,,MZT1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),gamma-tubulin complex localization [GO:0033566]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; microtubule nucleation by spindle pole body [GO:0051417]; mitotic spindle assembly [GO:0090307] comp143566_c0_seq1,1189,31.5391,0.51808245,48,10,,3.00E-15,Q5VV17,OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7),OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7),GO:0070536; GO:0006508; GO:0004843,protein K63-linked deubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,OTUD1_HUMAN,Homo sapiens (Human),protein K63-linked deubiquitination [GO:0070536] comp143566_c0_seq3,1672,32.9545,0.42714144,18,6,,2.00E-08,Q5T2D3,OTU domain-containing protein 3 (EC 3.4.19.12),OTU domain-containing protein 3 (EC 3.4.19.12),GO:0035871; GO:0044313; GO:0006508; GO:0004843,protein K11-linked deubiquitination; protein K6-linked deubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,OTUD3_HUMAN,Homo sapiens (Human),protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313] comp143566_c0_seq8,938,32.1962,0.42874803,0,0,,5.00E-15,Q5VV17,OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7),OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7),GO:0070536; GO:0006508; GO:0004843,protein K63-linked deubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,OTUD1_HUMAN,Homo sapiens (Human),protein K63-linked deubiquitination [GO:0070536] comp143568_c0_seq1,5050,37.1287,0.63693653,638,1436,,0,P25205,DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102),DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006270; GO:0006271; GO:0000082; GO:0042555; GO:0005658; GO:0005813; GO:0005654; GO:0048471,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication initiation; DNA strand elongation involved in DNA replication; G1/S transition of mitotic cell cycle; MCM complex; alpha DNA polymerase:primase complex; centrosome; nucleoplasm; perinuclear region of cytoplasm,PF00493;PF14551;,0,CHOYP_MCM3.1.1,,,,,,,MCM3_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082] comp143568_c0_seq2,4423,38.1641,0.63120021,21,545,,0,P25205,DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102),DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006270; GO:0006271; GO:0000082; GO:0042555; GO:0005658; GO:0005813; GO:0005654; GO:0048471,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication initiation; DNA strand elongation involved in DNA replication; G1/S transition of mitotic cell cycle; MCM complex; alpha DNA polymerase:primase complex; centrosome; nucleoplasm; perinuclear region of cytoplasm,PF00493;PF14551;,0,CHOYP_MCM3.1.1,,,9.00E-163,CU991150.p.cg.6,8,,MCM3_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082] comp143569_c1_seq2,923,38.6782,0.37986257,0,0,,2.00E-10,Q92982,Ninjurin-1 (Nerve injury-induced protein 1),Ninjurin-1 (Nerve injury-induced protein 1),GO:0007155; GO:0016021; GO:0007399; GO:0042246,cell adhesion; integral to membrane; nervous system development; tissue regeneration,PF04923;,,,,,,,,,NINJ1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; hyaloid vascular plexus regression [GO:1990384]; nervous system development [GO:0007399]; positive regulation of cell-matrix adhesion [GO:0001954]; tissue regeneration [GO:0042246] comp143571_c0_seq1,3507,37.8101,0.41557924,92,304,,6.00E-148,Q8VIJ8,Nitrogen permease regulator 3-like protein (Alpha-globin regulatory element-containing gene protein),Nitrogen permease regulator 3-like protein (Alpha-globin regulatory element-containing gene protein),GO:0005096; GO:0035909; GO:0048738; GO:0060021; GO:0043547; GO:0003281,GTPase activator activity; aorta morphogenesis; cardiac muscle tissue development; palate development; positive regulation of GTPase activity; ventricular septum development,PF03666;,1.00E-20,CHOYP_NPRL3.1.1,,,,,,,NPRL3_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; palate development [GO:0060021]; ventricular septum development [GO:0003281] comp143571_c0_seq3,3356,38.0215,0.42120663,110,282,,2.00E-148,Q8VIJ8,Nitrogen permease regulator 3-like protein (Alpha-globin regulatory element-containing gene protein),Nitrogen permease regulator 3-like protein (Alpha-globin regulatory element-containing gene protein),GO:0005096; GO:0035909; GO:0048738; GO:0060021; GO:0043547; GO:0003281,GTPase activator activity; aorta morphogenesis; cardiac muscle tissue development; palate development; positive regulation of GTPase activity; ventricular septum development,PF03666;,1.00E-20,CHOYP_NPRL3.1.1,,,,,,,NPRL3_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; palate development [GO:0060021]; ventricular septum development [GO:0003281] comp143573_c0_seq1,4514,43.0882,0.51721178,794,8891,,0,P35224,Catenin beta (Beta-catenin),Catenin beta (Beta-catenin),GO:0007155; GO:0005737; GO:0005856,cell adhesion; cytoplasm; cytoskeleton,PF00514;,0,CHOYP_ATC1.1.1,,,0,EW778397.p.cg.6,2,female gonad,CTNB_URECA,Urechis caupo (Innkeeper worm) (Spoonworm),adherens junction assembly [GO:0034333]; cell adhesion [GO:0007155] comp143574_c0_seq1,2888,41.8629,0.49347886,998,3123,,0,Q8C092,Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100),Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100),GO:0003677; GO:0006355; GO:0005669; GO:0006351,"DNA binding; regulation of transcription, DNA-dependent; transcription factor TFIID complex; transcription, DNA-dependent",PF04494;PF00400;,0,CHOYP_LOC101175542.1.1,,,,,,,TAF5_MOUSE,Mus musculus (Mouse),"DNA-templated transcription, initiation [GO:0006352]; histone acetylation [GO:0016573]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp143575_c0_seq1,5114,34.0438,0.40331355,0,0,,9.00E-50,Q9D5V6,Synapse-associated protein 1,Synapse-associated protein 1,GO:0005634,nucleus,PF03909;,3.00E-94,CHOYP_SYAP1.1.1,,,,,,,SYAP1_MOUSE,Mus musculus (Mouse), comp143575_c0_seq4,5022,33.9307,0.42029488,0,0,,3.00E-48,Q9D5V6,Synapse-associated protein 1,Synapse-associated protein 1,GO:0005634,nucleus,PF03909;,3.00E-94,CHOYP_SYAP1.1.1,,,,,,,SYAP1_MOUSE,Mus musculus (Mouse), comp143575_c0_seq5,2622,34.0198,0.45161852,28,163,,3.00E-49,Q9D5V6,Synapse-associated protein 1,Synapse-associated protein 1,GO:0005634,nucleus,PF03909;,9.00E-92,CHOYP_LOC574928.2.2,,,,,,,SYAP1_MOUSE,Mus musculus (Mouse), comp143575_c0_seq6,2718,34.106,0.4208742,0,0,,2.00E-50,Q96A49,Synapse-associated protein 1,Synapse-associated protein 1,GO:0005634,nucleus,PF03909;,2.00E-94,CHOYP_SYAP1.1.1,,,,,,,SYAP1_HUMAN,Homo sapiens (Human), comp143576_c0_seq1,3484,40.6716,0.71804371,1526,1187,,2.00E-28,Q90632,Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8),Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8),GO:0016021; GO:0005886; GO:0015355; GO:0015293,integral to membrane; plasma membrane; secondary active monocarboxylate transmembrane transporter activity; symporter activity,PF07690;,9.00E-36,CHOYP_IFIH1.11.14,2.00E-68,ruditapes_c15140,,,,,MOT3_CHICK,Gallus gallus (Chicken),plasma membrane lactate transport [GO:0035879] comp143579_c0_seq1,3647,36.6054,0.55682159,128,373,,5.00E-67,Q7JWR9,Zinc finger CCCH domain-containing protein 15 homolog (DRG family regulatory protein 1 homolog),Zinc finger CCCH domain-containing protein 15 homolog (DRG family regulatory protein 1 homolog),GO:0046872,metal ion binding,PF16543;PF16131;,1.00E-91,CHOYP_ZC3HF.1.1,,,,,,,ZC3HF_DROME,Drosophila melanogaster (Fruit fly), comp143579_c0_seq3,3669,36.5495,0.55517741,403,694,,2.00E-95,Q8WU90,Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4),Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4),GO:0019221; GO:0005737; GO:0046872; GO:0005730,cytokine-mediated signaling pathway; cytoplasm; metal ion binding; nucleolus,PF16543;PF00642;,,,,,,,,,ZC3HF_HUMAN,Homo sapiens (Human),cytokine-mediated signaling pathway [GO:0019221] comp143580_c0_seq1,707,45.686,0.38231967,90,123,,,,,,,,,1.00E-25,CHOYP_PAN2.1.1,,,,,,,,, comp143580_c0_seq2,3997,42.5069,0.58845717,1505,7218,,1.00E-173,Q5F450,PAB-dependent poly(A)-specific ribonuclease subunit 2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52),PAB-dependent poly(A)-specific ribonuclease subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-nuclease) (PAN deadenylation complex catalytic subunit 2),GO:0031251; GO:0000932; GO:0000184; GO:0003676; GO:0005634; GO:0004535; GO:0004221; GO:0006511,"PAN complex; cytoplasmic mRNA processing body; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleic acid binding; nucleus; poly(A)-specific ribonuclease activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process",PF00929;PF13423;,2.00E-109,CHOYP_PAN2.1.1,4.00E-13,ruditapes_lrc23561,,,,,PAN2_CHICK,Gallus gallus (Chicken),mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606] comp143581_c0_seq1,2635,41.1006,0.49669403,361,1530,,1.00E-81,Q9ESZ0,DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1),DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1),GO:0006284; GO:0003684; GO:0021766; GO:0005634; GO:0042493; GO:0001666; GO:0010033; GO:0000012,base-excision repair; damaged DNA binding; hippocampus development; nucleus; response to drug; response to hypoxia; response to organic substance; single strand break repair,PF00533;PF16589;PF01834;,7.00E-36,CHOYP_LOC591797.1.3,,,,,,,XRCC1_RAT,Rattus norvegicus (Rat),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012] comp143581_c0_seq2,730,44.1096,0.6543054,1,37,,1.00E-06,Q7ZU90,Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),GO:0005524; GO:0016887; GO:0003677; GO:0006281; GO:0006338; GO:0004386; GO:0000166; GO:0005634; GO:0006974,ATP binding; ATPase activity; DNA binding; DNA repair; chromatin remodeling; helicase activity; nucleotide binding; nucleus; response to DNA damage stimulus,PF00271;PF16759;PF00176;,,,,,,,,,CHD1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] comp143582_c0_seq10,2301,42.8075,0.5433293,4,0,,8.00E-172,Q13136,Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1),Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1),GO:0007160; GO:0005737; GO:0004871,cell-matrix adhesion; cytoplasm; signal transducer activity,PF00536;PF07647;,2.00E-163,CHOYP_BRAFLDRAFT_128281.1.1,,,,,,,LIPA1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165] comp143582_c0_seq4,4603,43.5585,0.62497741,0,0,,0,Q13136,Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1),Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1),GO:0007160; GO:0005737; GO:0004871,cell-matrix adhesion; cytoplasm; signal transducer activity,PF00536;PF07647;,0,CHOYP_LIPA1.1.1,,,,,,,LIPA1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165] comp143582_c0_seq5,2635,45.0854,0.70321371,0,0,,5.00E-150,Q21049,Liprin-alpha (LAR-interacting protein alpha) (Synapse defective protein 2),Liprin-alpha (LAR-interacting protein alpha) (Synapse defective protein 2),GO:0030424; GO:0008088; GO:0030054; GO:0005737; GO:0007626; GO:0007274; GO:0018991; GO:0097445; GO:0043113; GO:0030159; GO:0050803; GO:0050808,axon; axon cargo transport; cell junction; cytoplasm; locomotory behavior; neuromuscular synaptic transmission; oviposition; presynaptic active zone dense projection; receptor clustering; receptor signaling complex scaffold activity; regulation of synapse structure and activity; synapse organization,PF00536;PF07647;,,,,,,,,,LIPA_CAEEL,Caenorhabditis elegans,"axo-dendritic transport [GO:0008088]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular synaptic transmission [GO:0007274]; oviposition [GO:0018991]; positive regulation of anterograde synaptic vesicle transport [GO:1903744]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; protein localization [GO:0008104]; receptor clustering [GO:0043113]; regulation of synapse structure or activity [GO:0050803]; synapse organization [GO:0050808]; synaptic vesicle transport [GO:0048489]" comp143582_c0_seq6,544,40.625,0.9083364,2,0,,,,,,,,,,,6.00E-45,ruditapes_c6916,,,,,,, comp143582_c0_seq8,3892,43.3453,0.60202458,0,0,,0,Q13136,Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1),Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1),GO:0007160; GO:0005737; GO:0004871,cell-matrix adhesion; cytoplasm; signal transducer activity,PF00536;PF07647;,,,,,,,,,LIPA1_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165] comp143582_c0_seq9,3297,44.2827,0.61332413,0,0,,0,Q91Z80,Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4) (Fragment),Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4) (Fragment),GO:0009986; GO:0005737,cell surface; cytoplasm,PF00536;PF07647;,0,CHOYP_LIPA1.1.1,,,,,,,LIPA4_RAT,Rattus norvegicus (Rat), comp143583_c0_seq1,3021,39.8213,0.72669136,66,571,,0,Q8K3X3,"GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)","GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)",GO:0042351; GO:0008446; GO:0019673; GO:0070401; GO:0007219; GO:0005622,"'de novo' GDP-L-fucose biosynthetic process; GDP-mannose 4,6-dehydratase activity; GDP-mannose metabolic process; NADP+ binding; Notch signaling pathway; intracellular",PF16363;,5.00E-178,CHOYP_GMDS.1.1,,,,,,,GMDS_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; Notch signaling pathway [GO:0007219] comp143588_c0_seq1,2512,32.6035,0.94839293,340,2754,,2.00E-17,Q9W3W5,Protein shifted (WIF-1-like protein),Protein shifted (WIF-1-like protein),GO:0045880; GO:0050821; GO:0005578; GO:0007224; GO:0008039,positive regulation of smoothened signaling pathway; protein stabilization; proteinaceous extracellular matrix; smoothened signaling pathway; synaptic target recognition,PF12661;PF02019;,,,6.00E-22,ruditapes_c21382,,,,,WIF1_DROME,Drosophila melanogaster (Fruit fly),positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; regulation of smoothened signaling pathway [GO:0008589]; smoothened signaling pathway [GO:0007224]; synaptic target recognition [GO:0008039] comp143588_c0_seq2,1492,47.118,0.87952911,89,250,,5.00E-63,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp143589_c0_seq1,2392,41.7642,0.64151859,57,238,,4.00E-40,P23955,Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP),Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP),GO:0046872; GO:0004222; GO:0017087; GO:0006627; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial processing peptidase complex; protein processing involved in protein targeting to mitochondrion; proteolysis,PF00675;PF05193;,2.00E-41,CHOYP_MPPA.2.2,,,,,,,MPPA_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),protein processing involved in protein targeting to mitochondrion [GO:0006627] comp143589_c0_seq2,2364,41.7936,0.62773734,55,123,,4.00E-178,Q5R513,Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP),Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP),GO:0046872; GO:0004222; GO:0005759; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; proteolysis,PF00675;PF05193;,2.00E-41,CHOYP_MPPA.2.2,,,,,,,MPPA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp143590_c0_seq2,2587,36.9927,0.33917858,309,1851,,7.00E-31,Q92733,Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein),Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein),GO:0007093; GO:0005634,mitotic cell cycle checkpoint; nucleus,PF10253;,,,,,,,,,PRCC_HUMAN,Homo sapiens (Human),mitotic cell cycle checkpoint [GO:0007093] comp143592_c0_seq1,1920,36.4062,0.53996377,25,91,,2.00E-105,Q5SW45,Meckel syndrome type 1 protein homolog,Meckel syndrome type 1 protein homolog,GO:0036038; GO:0048754; GO:0005813; GO:0042384; GO:0005737; GO:0016020; GO:0005932,TCTN-B9D complex; branching morphogenesis of an epithelial tube; centrosome; cilium assembly; cytoplasm; membrane; microtubule basal body,PF07162;,4.00E-119,CHOYP_BRAFLDRAFT_279949.1.1,,,,,,,MKS1_MOUSE,Mus musculus (Mouse),"branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor stereocilium organization [GO:0060122]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]" comp143592_c0_seq2,2351,37.8988,0.5862712,24,8,,7.00E-136,Q5SW45,Meckel syndrome type 1 protein homolog,Meckel syndrome type 1 protein homolog,GO:0036038; GO:0048754; GO:0005813; GO:0042384; GO:0005737; GO:0016020; GO:0005932,TCTN-B9D complex; branching morphogenesis of an epithelial tube; centrosome; cilium assembly; cytoplasm; membrane; microtubule basal body,PF07162;,,,,,,,,,MKS1_MOUSE,Mus musculus (Mouse),"branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor stereocilium organization [GO:0060122]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]" comp143592_c0_seq3,1070,40.3738,0.55477904,0,0,,8.00E-10,Q56JY9,B9 domain-containing protein 2,B9 domain-containing protein 2,GO:0036038; GO:0005813; GO:0042384; GO:0035085; GO:0043015; GO:0005932; GO:0005634,TCTN-B9D complex; centrosome; cilium assembly; cilium axoneme; gamma-tubulin binding; microtubule basal body; nucleus,PF07162;,,,,,,,,,B9D2_BOVIN,Bos taurus (Bovine),cilium assembly [GO:0042384] comp143593_c1_seq1,2300,42.2174,1.03330388,3,1574,female>male,2.00E-60,P35903,Achacin,Achacin,GO:0042742; GO:0016491,defense response to bacterium; oxidoreductase activity,PF01593;,,,,,,,,,ACHC_ACHFU,Achatina fulica (Giant African snail),defense response to bacterium [GO:0042742] comp143593_c1_seq2,1997,42.1132,1.04978952,2,535,female>male,2.00E-64,Q17043,Aplysianin-A,Aplysianin-A,GO:0042742; GO:0016491,defense response to bacterium; oxidoreductase activity,PF01593;,,,,,,,,,APLY_APLKU,Aplysia kurodai (Kuroda's sea hare),defense response to bacterium [GO:0042742] comp143599_c0_seq1,3460,44.0173,0.43066461,732,7101,,0,Q6PF21,"Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)","Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)",GO:0005524; GO:0005737; GO:0004825; GO:0006431; GO:0000049,ATP binding; cytoplasm; methionine-tRNA ligase activity; methionyl-tRNA aminoacylation; tRNA binding,PF14497;PF09334;PF00458;,0,CHOYP_SYMC.1.1,,,,,,,SYMC_XENLA,Xenopus laevis (African clawed frog),methionyl-tRNA aminoacylation [GO:0006431] comp143602_c0_seq1,3742,42.2769,0.32690752,439,1719,,0,Q8IY37,Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37),Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_LOC101173065.1.1,,,,,,,DHX37_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396]; rRNA processing [GO:0006364] comp143604_c0_seq1,2949,37.6738,0.58861441,894,1333,,0,Q148D5,"Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)","Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)",GO:0005524; GO:0046872; GO:0005739; GO:0004775; GO:0006099,ATP binding; metal ion binding; mitochondrion; succinate-CoA ligase (ADP-forming) activity; tricarboxylic acid cycle,PF08442;PF00549;,2.00E-100,CHOYP_SUCB1.1.1,1.00E-87,ruditapes_c18048,,,,,SUCB1_BOVIN,Bos taurus (Bovine),tricarboxylic acid cycle [GO:0006099] comp143606_c0_seq3,2760,38.5145,0.53101834,5988,727,,4.00E-26,Q6AXP4,Uncharacterized protein C2orf81 homolog,Uncharacterized protein C2orf81 homolog,,,PF15479;,1.00E-45,CHOYP_LOC100369816.1.1,,,,,,,CB081_RAT,Rattus norvegicus (Rat), comp143608_c0_seq1,1778,42.6884,0.32136465,544,2307,,0,Q28BR5,"Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)","Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)",GO:0046872; GO:0004222; GO:0005759; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; proteolysis,PF08367;PF00675;PF05193;,,,,,,,,,PREP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein processing [GO:0016485]; proteolysis [GO:0006508] comp143608_c0_seq2,943,42.4178,0.37820555,86,380,,6.00E-91,Q759T9,Mitochondrial presequence protease (EC 3.4.24.-),Mitochondrial presequence protease (EC 3.4.24.-),GO:0046872; GO:0008237; GO:0005739; GO:0051603,metal ion binding; metallopeptidase activity; mitochondrion; proteolysis involved in cellular protein catabolic process,PF08367;PF00675;PF05193;,,,,,,,,,CYM1_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),protein processing [GO:0016485]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp143608_c1_seq1,632,39.7152,0.52689337,105,717,,5.00E-24,Q6BTC0,Mitochondrial presequence protease (EC 3.4.24.-),Mitochondrial presequence protease (EC 3.4.24.-),GO:0046872; GO:0008237; GO:0005739; GO:0006508,metal ion binding; metallopeptidase activity; mitochondrion; proteolysis,PF08367;PF00675;PF05193;,,,,,,,,,CYM1_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),proteolysis involved in cellular protein catabolic process [GO:0051603] comp143608_c1_seq2,607,40.3624,0.45201528,164,709,,3.00E-39,Q28BR5,"Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)","Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)",GO:0046872; GO:0004222; GO:0005759; GO:0006508,metal ion binding; metalloendopeptidase activity; mitochondrial matrix; proteolysis,PF08367;PF00675;PF05193;,,,,,,,,,PREP_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein processing [GO:0016485]; proteolysis [GO:0006508] comp143609_c0_seq2,1525,44.7869,0.50880078,65,628,,6.00E-89,Q08B12,Cytoplasmic tRNA 2-thiolation protein 2-A,Cytoplasmic tRNA 2-thiolation protein 2-A,GO:0005829; GO:0000049; GO:0034227; GO:0002098,cytosol; tRNA binding; tRNA thio-modification; tRNA wobble uridine modification,PF10288;,1.00E-36,CHOYP_CTU2.1.1,,,,,,,CTU2A_XENLA,Xenopus laevis (African clawed frog),protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] comp143611_c0_seq1,1461,34.2916,0.42248928,0,5,,,,,,,,,,,7.00E-18,ruditapes_c2726,,,,,,, comp143611_c0_seq5,2445,36.3599,0.38748422,0,0,,,,,,,,,,,8.00E-39,ruditapes_c27988,,,,,,, comp143611_c0_seq6,633,34.5972,0.26598489,0,11,,,,,,,,,,,3.00E-12,ruditapes_lrc19277,,,,,,, comp143611_c1_seq2,1428,35.1541,0.43294765,192,569,,1.00E-26,A5D6V4,Transmembrane protein 17B,Transmembrane protein 17B,GO:0036038; GO:0042384; GO:0060170; GO:0016021; GO:0007224,TCTN-B9D complex; cilium assembly; cilium membrane; integral to membrane; smoothened signaling pathway,PF09799;,2.00E-51,CHOYP_BRAFLDRAFT_90803.1.1,,,,,,,TM17B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; smoothened signaling pathway [GO:0007224] comp143612_c0_seq1,4712,46.6469,0.44372173,1927,0,male,0,Q8BW94,"Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3)","Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3)",GO:0005524; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,0,CHOYP_LOC100378331.1.1,3.00E-16,ruditapes_c10161,,,,,DYH3_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp143612_c0_seq2,2723,45.5747,0.45368815,181,0,,,,,,,,,0,CHOYP_LOC100378331.1.1,,,,,,,,, comp143613_c0_seq1,1019,43.5721,0.21164042,26,9,,,,,,,,,1.00E-33,CHOYP_LOC100376482.1.7,,,,,,,,, comp143613_c0_seq4,473,42.0719,0.15290391,31,105,,,,,,,,,2.00E-22,CHOYP_LOC100635407.2.3,,,,,,,,, comp143614_c1_seq1,3202,37.0394,0.61889442,11,237,,8.00E-42,Q9VGG5,Cadherin-87A,Cadherin-87A,GO:0005509; GO:0016339; GO:0007156; GO:0005887,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to plasma membrane,PF00028;,,,,,,,,,CAD87_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp143617_c0_seq3,3096,41.9897,0.68098671,11,2,,,,,,,,,6.00E-88,CHOYP_LOC584318.1.1,,,,,,,,, comp143617_c0_seq5,3016,41.8767,0.68873866,4,0,,2.00E-73,Q6A098,Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like),Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like),,,PF01248;,6.00E-88,CHOYP_LOC584318.1.1,,,,,,,SBP2L_MOUSE,Mus musculus (Mouse), comp143618_c1_seq1,3167,37.0382,0.71120448,10,15,,3.00E-07,Q6E2N3,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TRI33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp143618_c1_seq2,2793,38.4533,0.70093389,23,112,,2.00E-08,O15164,Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24),GO:0055074; GO:0071391; GO:0003682; GO:0005829; GO:0034056; GO:0070577; GO:0008285; GO:0045892; GO:0005719; GO:0005634; GO:0005726; GO:0045893; GO:0046777; GO:0030163; GO:0004672; GO:0005102; GO:0042981; GO:0031647; GO:0070562; GO:0043565; GO:0003713; GO:0006366; GO:0004842; GO:0008270,"calcium ion homeostasis; cellular response to estrogen stimulus; chromatin binding; cytosol; estrogen response element binding; histone acetyl-lysine binding; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nuclear euchromatin; nucleus; perichromatin fibrils; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein catabolic process; protein kinase activity; receptor binding; regulation of apoptotic process; regulation of protein stability; regulation of vitamin D receptor signaling pathway; sequence-specific DNA binding; transcription coactivator activity; transcription from RNA polymerase II promoter; ubiquitin-protein ligase activity; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TIF1A_HUMAN,Homo sapiens (Human),"calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]" comp143620_c1_seq1,4545,38.0858,0.45450175,198,523,,0,Q28BT8,tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like),tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like),GO:0050660; GO:0046872; GO:0017150; GO:0002943,flavin adenine dinucleotide binding; metal ion binding; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF01207;,2.00E-152,CHOYP_LOC100377501.1.1,,,,,,,DUS3L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143620_c1_seq4,4548,38.0607,0.45480169,148,525,,0,Q28BT8,tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like),tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like),GO:0050660; GO:0046872; GO:0017150; GO:0002943,flavin adenine dinucleotide binding; metal ion binding; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF01207;,2.00E-152,CHOYP_LOC100377501.1.1,,,,,,,DUS3L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp143622_c0_seq1,3149,42.5849,0.31824614,324,2002,,3.00E-27,Q14146,Unhealthy ribosome biogenesis protein 2 homolog,Unhealthy ribosome biogenesis protein 2 homolog,GO:0005730,nucleolus,PF10441;,,,,,,,,,URB2_HUMAN,Homo sapiens (Human), comp143622_c0_seq2,646,38.5449,0.54334756,551,1574,,4.00E-20,Q14146,Unhealthy ribosome biogenesis protein 2 homolog,Unhealthy ribosome biogenesis protein 2 homolog,GO:0005730,nucleolus,PF10441;,,,,,,,,,URB2_HUMAN,Homo sapiens (Human), comp143623_c0_seq2,2595,43.8536,0.41468096,19,198,,6.00E-62,Q58HI1,"Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor)","Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor)",GO:0071339; GO:0005737; GO:0006351,"MLL1 complex; cytoplasm; transcription, DNA-dependent",PF08166;PF08167;,,,,,,,,,PELP1_XENLA,Xenopus laevis (African clawed frog),"cellular response to estrogen stimulus [GO:0071391]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp143624_c0_seq11,2124,30.791,0.77563472,9,4,,8.00E-14,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143624_c0_seq15,1511,31.2376,0.73680253,0,0,,4.00E-09,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp143624_c0_seq16,792,31.0606,0.73620807,0,0,,4.00E-07,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143624_c0_seq2,2279,30.4081,0.66472316,0,0,,5.00E-11,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143624_c0_seq7,2112,30.6345,0.78811632,0,0,,7.00E-14,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143624_c1_seq1,363,32.2314,0.64387281,61,42,,5.00E-08,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp143625_c0_seq1,2908,37.0014,0.51267889,45,52,,2.00E-51,Q12523,WD repeat-containing protein YPL247C,WD repeat-containing protein YPL247C,GO:0005737; GO:0005634,cytoplasm; nucleus,PF00400;,,,,,,,,,YP247_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp143625_c0_seq3,2890,37.1972,0.50056452,92,95,,0,P61963,DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog),DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog),GO:0080008; GO:0005737; GO:0007275; GO:0005634; GO:0016567,Cul4-RING ubiquitin ligase complex; cytoplasm; multicellular organismal development; nucleus; protein ubiquitination,,0,CHOYP_DCAF7.1.1,,,,,,,DCAF7_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; protein ubiquitination [GO:0016567] comp143626_c0_seq1,4168,37.8599,0.49939462,626,1303,,9.00E-105,P59326,YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog),YTH domain-containing family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog),,,PF04146;,5.00E-103,CHOYP_LOC100371022.1.1,,,8.00E-76,CU994233.p.cg.6,3,,YTHD1_MOUSE,Mus musculus (Mouse),positive regulation of translational initiation [GO:0045948] comp143628_c0_seq1,4353,43.6481,0.2425216,414,581,,5.00E-70,Q869L3,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0006200; GO:0016887; GO:0005634; GO:0006461,ATP binding; ATP catabolic process; ATPase activity; nucleus; protein complex assembly,PF07728;,8.00E-133,CHOYP_MDN1.4.8,,,,,,,MDN1_DICDI,Dictyostelium discoideum (Slime mold),ribosomal large subunit assembly [GO:0000027] comp143628_c0_seq4,779,47.1117,0.53421564,0,7,,6.00E-96,Q9NU22,Midasin (MIDAS-containing protein),Midasin (MIDAS-containing protein),GO:0005524; GO:0016887; GO:0005730; GO:0005634; GO:0006461; GO:0051082,ATP binding; ATPase activity; nucleolus; nucleus; protein complex assembly; unfolded protein binding,PF07728;,2.00E-99,CHOYP_MDN1.4.8,,,,,,,MDN1_HUMAN,Homo sapiens (Human),protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027] comp14362_c0_seq1,243,38.6831,0.99458206,7,0,,3.00E-06,Q9NYQ6,Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007417; GO:0048105; GO:0001736; GO:0042249; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity; establishment of planar polarity of embryonic epithelium; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp143633_c0_seq1,2061,43.28,0.48963902,176,913,,3.00E-68,Q80YF0,Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1),Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1),GO:0051301; GO:0000777; GO:0005737; GO:0000776; GO:0005815; GO:0007067; GO:0072686; GO:0007094; GO:0005634; GO:0090235,cell division; condensed chromosome kinetochore; cytoplasm; kinetochore; microtubule organizing center; mitosis; mitotic spindle; mitotic spindle assembly checkpoint; nucleus; regulation of metaphase plate congression,PF05557;,2.00E-16,CHOYP_MYSP.6.9,,,,,,,MD1L1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of metaphase plate congression [GO:0090235] comp143634_c0_seq1,2339,39.4613,0.50088961,0,0,,7.00E-94,Q9I7I0,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B3,GO:0007067; GO:0000281; GO:0005634; GO:0010389; GO:0035561; GO:0000079; GO:0035186,mitosis; mitotic cytokinesis; nucleus; regulation of G2/M transition of mitotic cell cycle; regulation of chromatin binding; regulation of cyclin-dependent protein serine/threonine kinase activity; syncytial blastoderm mitotic cell cycle,PF02984;PF00134;,2.00E-99,CHOYP_CCNB3.1.1,,,,,,,CCNB3_DROME,Drosophila melanogaster (Fruit fly),cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186] comp143634_c0_seq11,1843,39.338,0.55811154,0,0,,2.00E-93,Q9I7I0,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B3,GO:0007067; GO:0000281; GO:0005634; GO:0010389; GO:0035561; GO:0000079; GO:0035186,mitosis; mitotic cytokinesis; nucleus; regulation of G2/M transition of mitotic cell cycle; regulation of chromatin binding; regulation of cyclin-dependent protein serine/threonine kinase activity; syncytial blastoderm mitotic cell cycle,PF02984;PF00134;,2.00E-99,CHOYP_CCNB3.1.1,1.00E-28,ruditapes_c18722,,,,,CCNB3_DROME,Drosophila melanogaster (Fruit fly),cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186] comp143634_c0_seq12,2570,39.3385,0.50855713,0,0,,4.00E-51,P51988,G2/mitotic-specific cyclin-B (Fragment),G2/mitotic-specific cyclin-B (Fragment),GO:0051301; GO:0007067; GO:0005634; GO:0000079,cell division; mitosis; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,,,,,,,,,CCNB_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp143634_c0_seq4,1853,39.6654,0.55883788,0,0,,2.00E-93,Q9I7I0,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B3,GO:0007067; GO:0000281; GO:0005634; GO:0010389; GO:0035561; GO:0000079; GO:0035186,mitosis; mitotic cytokinesis; nucleus; regulation of G2/M transition of mitotic cell cycle; regulation of chromatin binding; regulation of cyclin-dependent protein serine/threonine kinase activity; syncytial blastoderm mitotic cell cycle,PF02984;PF00134;,,,,,,,,,CCNB3_DROME,Drosophila melanogaster (Fruit fly),cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186] comp143634_c0_seq5,2755,38.6207,0.54247316,0,0,,7.00E-51,P51988,G2/mitotic-specific cyclin-B (Fragment),G2/mitotic-specific cyclin-B (Fragment),GO:0051301; GO:0007067; GO:0005634; GO:0000079,cell division; mitosis; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,,,,,,,,,CCNB_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp143634_c0_seq6,1855,39.1375,0.54559114,0,0,,1.00E-76,Q10654,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B3,GO:0051301; GO:0007098; GO:0016538; GO:0005737; GO:0051383; GO:0045144; GO:0000070; GO:0005634; GO:0001556; GO:0045842; GO:0001934; GO:0035046; GO:0010389; GO:0000079,cell division; centrosome cycle; cyclin-dependent protein serine/threonine kinase regulator activity; cytoplasm; kinetochore organization; meiotic sister chromatid segregation; mitotic sister chromatid segregation; nucleus; oocyte maturation; positive regulation of mitotic metaphase/anaphase transition; positive regulation of protein phosphorylation; pronuclear migration; regulation of G2/M transition of mitotic cell cycle; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,2.00E-99,CHOYP_CCNB3.1.1,,,,,,,CCNB3_CAEEL,Caenorhabditis elegans,cell division [GO:0051301]; centrosome cycle [GO:0007098]; kinetochore organization [GO:0051383]; meiotic sister chromatid segregation [GO:0045144]; mitotic sister chromatid segregation [GO:0000070]; oocyte maturation [GO:0001556]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein phosphorylation [GO:0001934]; pronuclear migration [GO:0035046]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of meiotic cell cycle [GO:0051445] comp143634_c0_seq8,1865,39.4102,0.54879885,0,0,,2.00E-93,Q9I7I0,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B3,GO:0007067; GO:0000281; GO:0005634; GO:0010389; GO:0035561; GO:0000079; GO:0035186,mitosis; mitotic cytokinesis; nucleus; regulation of G2/M transition of mitotic cell cycle; regulation of chromatin binding; regulation of cyclin-dependent protein serine/threonine kinase activity; syncytial blastoderm mitotic cell cycle,PF02984;PF00134;,2.00E-99,CHOYP_CCNB3.1.1,,,,,,,CCNB3_DROME,Drosophila melanogaster (Fruit fly),cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186] comp143634_c0_seq9,2583,39.2567,0.51751445,1,7,,5.00E-51,P51988,G2/mitotic-specific cyclin-B (Fragment),G2/mitotic-specific cyclin-B (Fragment),GO:0051301; GO:0007067; GO:0005634; GO:0000079,cell division; mitosis; nucleus; regulation of cyclin-dependent protein serine/threonine kinase activity,PF02984;PF00134;,,,,,,,,,CCNB_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp143636_c1_seq1,1594,44.4793,0.64938792,344,554,,2.00E-34,Q9JIX8,Apoptotic chromatin condensation inducer in the nucleus (Acinus),Apoptotic chromatin condensation inducer in the nucleus (Acinus),GO:0061574; GO:0030263; GO:0005737; GO:0030218; GO:0048025; GO:0016607; GO:0003676; GO:0005730; GO:0000166; GO:0043065; GO:0045657,"ASAP complex; apoptotic chromosome condensation; cytoplasm; erythrocyte differentiation; negative regulation of mRNA splicing, via spliceosome; nuclear speck; nucleic acid binding; nucleolus; nucleotide binding; positive regulation of apoptotic process; positive regulation of monocyte differentiation",PF16294;PF02037;,,,,,,,,,ACINU_MOUSE,Mus musculus (Mouse),"apoptotic chromosome condensation [GO:0030263]; apoptotic process [GO:0006915]; erythrocyte differentiation [GO:0030218]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of monocyte differentiation [GO:0045657]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]; xenophagy [GO:0098792]" comp143637_c2_seq3,2965,41.4165,0.42048561,1,0,,2.00E-144,P51612,DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125),DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125),GO:0071942; GO:0005737; GO:0003684; GO:0031573; GO:0006289; GO:0000715; GO:0010224; GO:0003697,"XPC complex; cytoplasm; damaged DNA binding; intra-S DNA damage checkpoint; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; response to UV-B; single-stranded DNA binding",PF10403;PF10404;PF10405;PF03835;,2.00E-118,CHOYP_XPC.1.1,,,,,,,XPC_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]" comp143637_c2_seq4,2478,41.2833,0.45752383,0,0,,2.00E-123,P51612,DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125),DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125),GO:0071942; GO:0005737; GO:0003684; GO:0031573; GO:0006289; GO:0000715; GO:0010224; GO:0003697,"XPC complex; cytoplasm; damaged DNA binding; intra-S DNA damage checkpoint; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; response to UV-B; single-stranded DNA binding",PF10403;PF10404;PF10405;PF03835;,2.00E-118,CHOYP_XPC.1.1,,,,,,,XPC_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]" comp143639_c0_seq4,3362,46.0143,0.39073049,331,47,,0,Q9Y4D8,Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4),GO:0005737; GO:0016021; GO:0005634; GO:0042787; GO:0004842,cytoplasm; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,9.00E-131,CHOYP_RGD1309762.1.1,,,,,,,HECD4_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp143639_c0_seq5,1401,43.0407,0.38983448,0,12,,,,,,,,,7.00E-14,CHOYP_RGD1309762.1.1,,,,,,,,, comp143640_c1_seq1,3581,42.8651,0.45149497,20,87,,0,O96028,Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.43) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (NSD2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) (WHSC1),Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.43) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (NSD2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) (WHSC1),GO:0003677; GO:0009653; GO:0003289; GO:0003290; GO:0060348; GO:0003682; GO:0005694; GO:0005737; GO:0018024; GO:0003149; GO:0000122; GO:0031965; GO:0005730; GO:0006351; GO:0008270,"DNA binding; anatomical structure morphogenesis; atrial septum primum morphogenesis; atrial septum secundum morphogenesis; bone development; chromatin binding; chromosome; cytoplasm; histone-lysine N-methyltransferase activity; membranous septum morphogenesis; negative regulation of transcription from RNA polymerase II promoter; nuclear membrane; nucleolus; transcription, DNA-dependent; zinc ion binding",PF00505;PF00855;PF00856;,3.00E-125,CHOYP_WHSC1.1.1,,,,,,,NSD2_HUMAN,Homo sapiens (Human),"anatomical structure morphogenesis [GO:0009653]; atrial septum primum morphogenesis [GO:0003289]; atrial septum secundum morphogenesis [GO:0003290]; bone development [GO:0060348]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 methylation [GO:0010452]; membranous septum morphogenesis [GO:0003149]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of establishment of protein localization [GO:0070201]; transcription, DNA-templated [GO:0006351]" comp143640_c1_seq2,1301,41.1222,0.51759124,134,328,,1.00E-11,Q6IR42,Zinc finger CW-type PWWP domain protein 1,Zinc finger CW-type PWWP domain protein 1,GO:0008270,zinc ion binding,PF00855;PF07496;,,,,,,,,,ZCPW1_MOUSE,Mus musculus (Mouse), comp143640_c1_seq3,1152,42.3611,0.55801615,0,0,,3.00E-10,Q9SIV5,Zinc finger CCCH domain-containing protein 19 (AtC3H19) (Protein Needed for RDR2-independent DNA methylation),Zinc finger CCCH domain-containing protein 19 (AtC3H19) (Protein Needed for RDR2-independent DNA methylation),GO:0003677; GO:0032776; GO:0006352; GO:0031047; GO:0042393; GO:0016570; GO:0005634; GO:0010964; GO:0008270,"DNA binding; DNA methylation on cytosine; DNA-dependent transcription, initiation; gene silencing by RNA; histone binding; histone modification; nucleus; regulation of chromatin silencing by small RNA; zinc ion binding",PF02213;PF03126;PF02201;PF00642;,,,,,,,,,C3H19_ARATH,Arabidopsis thaliana (Mouse-ear cress),"DNA methylation on cytosine [GO:0032776]; gene silencing by RNA [GO:0031047]; regulation of chromatin silencing by small RNA [GO:0010964]; transcription, DNA-templated [GO:0006351]" comp143641_c0_seq1,5272,39.5486,0.43941668,31,295,,8.00E-165,P20742,Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6),Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6),GO:0004866; GO:0005615; GO:0070062; GO:0007565; GO:0004867,endopeptidase inhibitor activity; extracellular space; extracellular vesicular exosome; female pregnancy; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,PZP_HUMAN,Homo sapiens (Human),female pregnancy [GO:0007565] comp143641_c0_seq2,5305,39.7172,0.4474227,49,355,,7.00E-163,P14046,Alpha-1-inhibitor 3 (Alpha-1-inhibitor 3 variant II) (Alpha-1-inhibitor III),Alpha-1-inhibitor 3 (Alpha-1-inhibitor 3 variant II) (Alpha-1-inhibitor III),GO:0005615; GO:0006954; GO:0010951; GO:0030414; GO:0004867,extracellular space; inflammatory response; negative regulation of endopeptidase activity; peptidase inhibitor activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,A1I3_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954] comp143642_c1_seq1,254,36.2205,0.60513515,8,0,,,,,,,,,,,9.00E-14,ruditapes_lrc13794,,,,,,, comp143645_c0_seq2,831,44.645,0.44171843,38,77,,1.00E-89,Q9CWD8,Iron-sulfur protein NUBPL (Nucleotide-binding protein-like),Iron-sulfur protein NUBPL (Nucleotide-binding protein-like),GO:0051539; GO:0005524; GO:0046872; GO:0032981; GO:0005739; GO:0070584,"4 iron, 4 sulfur cluster binding; ATP binding; metal ion binding; mitochondrial respiratory chain complex I assembly; mitochondrion; mitochondrion morphogenesis",PF10609;,3.00E-78,CHOYP_NUBPL.1.1,,,,,,,NUBPL_MOUSE,Mus musculus (Mouse),mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion morphogenesis [GO:0070584] comp143648_c0_seq2,2243,36.9594,0.3021462,25,51,,0,O88544,COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4),COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4),GO:0008180; GO:0010388; GO:0005737,COP9 signalosome; cullin deneddylation; cytoplasm,PF01399;,,,,,,,,,CSN4_MOUSE,Mus musculus (Mouse),cullin deneddylation [GO:0010388]; protein deneddylation [GO:0000338] comp143648_c0_seq4,1859,37.9236,0.28590853,0,0,,0,O88544,COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4),COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4),GO:0008180; GO:0010388; GO:0005737,COP9 signalosome; cullin deneddylation; cytoplasm,PF01399;,0,CHOYP_CSN4.1.1,1.00E-168,ruditapes_c10118,,,,,CSN4_MOUSE,Mus musculus (Mouse),cullin deneddylation [GO:0010388]; protein deneddylation [GO:0000338] comp143651_c2_seq2,1441,31.2977,0.46162487,0,0,,,,,,,,,4.00E-36,CHOYP_NEMVEDRAFT_V1G169659.2.2,,,,,,,,, comp143651_c2_seq3,1476,31.0976,0.48529207,0,0,,7.00E-29,Q6TAW2,Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2),Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2),GO:0005789; GO:0016021; GO:0015031,endoplasmic reticulum membrane; integral to membrane; protein transport,PF06624;,,,,,,,,,SERP2_MOUSE,Mus musculus (Mouse),endoplasmic reticulum unfolded protein response [GO:0030968]; protein glycosylation [GO:0006486]; protein transport [GO:0015031] comp143651_c2_seq4,1465,31.058,0.48976166,0,0,,7.00E-29,Q6TAW2,Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2),Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2),GO:0005789; GO:0016021; GO:0015031,endoplasmic reticulum membrane; integral to membrane; protein transport,PF06624;,4.00E-36,CHOYP_NEMVEDRAFT_V1G169659.1.2,2.00E-51,ruditapes2_c149,,,,,SERP2_MOUSE,Mus musculus (Mouse),endoplasmic reticulum unfolded protein response [GO:0030968]; protein glycosylation [GO:0006486]; protein transport [GO:0015031] comp143652_c0_seq1,1719,41.1867,0.52065545,130,457,,4.00E-96,Q5F1R6,DnaJ homolog subfamily C member 21 (DnaJ homolog subfamily A member 5) (Protein GS3),DnaJ homolog subfamily C member 21 (DnaJ homolog subfamily A member 5) (Protein GS3),GO:0003676; GO:0006457; GO:0005840; GO:0008270,nucleic acid binding; protein folding; ribosome; zinc ion binding,PF00226;PF12171;,7.00E-78,CHOYP_NEMVEDRAFT_V1G201862.1.1,,,,,,,DJC21_HUMAN,Homo sapiens (Human),protein folding [GO:0006457] comp143652_c0_seq3,225,37.3333,0.95073993,6,21,,4.00E-14,Q5FWN8,DnaJ homolog subfamily B member 6-A,DnaJ homolog subfamily B member 6-A,GO:0005634; GO:0048471,nucleus; perinuclear region of cytoplasm,PF00226;,6.00E-11,CHOYP_DNAJB6B.2.2,,,,,,,DNJ6A_XENLA,Xenopus laevis (African clawed frog), comp143654_c0_seq1,2019,37.5929,0.67158072,0,0,,6.00E-49,P49760,Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2),Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2),GO:0005524; GO:0045721; GO:0016607; GO:0005634; GO:0046777; GO:0004674; GO:0004712; GO:0004713; GO:0043484; GO:0010212; GO:0032526,ATP binding; negative regulation of gluconeogenesis; nuclear speck; nucleus; protein autophosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; regulation of RNA splicing; response to ionizing radiation; response to retinoic acid,PF00069;,,,,,,,,,CLK2_HUMAN,Homo sapiens (Human),negative regulation of gluconeogenesis [GO:0045721]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212]; response to retinoic acid [GO:0032526] comp143654_c0_seq2,1830,36.9945,0.66890335,0,0,,5.00E-44,P14680,Dual specificity protein kinase YAK1 (EC 2.7.12.1),Dual specificity protein kinase YAK1 (EC 2.7.12.1),GO:0005524; GO:0005737; GO:0005634; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; nucleus; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00069;,,,,,,,,,YAK1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]" comp143654_c0_seq3,1921,37.012,0.68349947,1,19,,3.00E-32,Q3V016,Homeodomain-interacting protein kinase 4 (EC 2.7.11.1),Homeodomain-interacting protein kinase 4 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0004674,ATP binding; cytoplasm; protein serine/threonine kinase activity,PF00069;,,,,,,,,,HIPK4_MOUSE,Mus musculus (Mouse),histone phosphorylation [GO:0016572]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796] comp143654_c0_seq4,1897,37.4802,0.65752008,0,0,,0,Q5R814,Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog),Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog),GO:0005524; GO:0008380; GO:0006397; GO:0004674; GO:0005681,ATP binding; RNA splicing; mRNA processing; protein serine/threonine kinase activity; spliceosomal complex,PF00069;,7.00E-180,CHOYP_PRP4B.1.1,,,,,,,PRP4B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp143654_c0_seq7,1952,37.1414,0.68313271,0,0,,0,Q5R814,Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog),Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog),GO:0005524; GO:0008380; GO:0006397; GO:0004674; GO:0005681,ATP binding; RNA splicing; mRNA processing; protein serine/threonine kinase activity; spliceosomal complex,PF00069;,1.00E-164,CHOYP_PRP4B.1.1,,,,,,,PRP4B_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp143654_c0_seq8,1799,36.8538,0.66892139,0,0,,3.00E-43,Q54BC9,Probable serine/threonine-protein kinase dyrk2 (EC 2.7.12.1) (Dual specificity tyrosine-phosphorylation-regulated kinase 2),Probable serine/threonine-protein kinase dyrk2 (EC 2.7.12.1) (Dual specificity tyrosine-phosphorylation-regulated kinase 2),GO:0005524; GO:0005737; GO:0006468; GO:0004674; GO:0004712,ATP binding; cytoplasm; protein phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity,PF00069;,,,,,,,,,DYRK2_DICDI,Dictyostelium discoideum (Slime mold), comp143654_c2_seq2,744,41.6667,0.51064964,104,272,,,,,,,,,,,1.00E-18,ruditapes_c21085,,,,,,, comp143655_c0_seq1,2937,41.6411,0.3335929,205,1383,,2.00E-135,Q91W96,Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4),Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4),GO:0005680; GO:0031145; GO:0051301; GO:0007067; GO:0070979; GO:0030071,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; mitosis; protein K11-linked ubiquitination; regulation of mitotic metaphase/anaphase transition,PF12896;PF12894;,3.00E-110,CHOYP_ANAPC4.1.2,,,,,,,APC4_MOUSE,Mus musculus (Mouse),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071] comp143656_c0_seq2,2166,40.12,0.36913693,85,505,,0,Q5ZHS1,Elongator complex protein 3 (EC 2.3.1.48),Elongator complex protein 3 (EC 2.3.1.48),GO:0003677; GO:0016591; GO:0033588; GO:0005737; GO:0016573; GO:0004402; GO:0051536; GO:0046872; GO:0005730; GO:0008607; GO:0006357; GO:0008023; GO:0006368,"DNA binding; DNA-directed RNA polymerase II, holoenzyme; Elongator holoenzyme complex; cytoplasm; histone acetylation; histone acetyltransferase activity; iron-sulfur cluster binding; metal ion binding; nucleolus; phosphorylase kinase regulator activity; regulation of transcription from RNA polymerase II promoter; transcription elongation factor complex; transcription elongation from RNA polymerase II promoter",PF00583;PF04055;PF16199;,0,CHOYP_LOC100373199.1.1,,,,,,,ELP3_CHICK,Gallus gallus (Chicken),central nervous system development [GO:0007417]; neuron migration [GO:0001764]; positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]; tRNA wobble uridine modification [GO:0002098] comp143657_c0_seq1,1623,37.215,0.77492123,95,527,,7.00E-50,Q76MJ5,Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0030263; GO:0007050; GO:0004519; GO:0005789; GO:0016021; GO:0006397; GO:0000287; GO:0045892; GO:0004674; GO:0016075; GO:0006950; GO:0004540; GO:0006351,"ATP binding; apoptotic chromosome condensation; cell cycle arrest; endonuclease activity; endoplasmic reticulum membrane; integral to membrane; mRNA processing; magnesium ion binding; negative regulation of transcription, DNA-dependent; protein serine/threonine kinase activity; rRNA catabolic process; response to stress; ribonuclease activity; transcription, DNA-dependent",PF00069;PF06479;,,,,,,,,,ERN2_HUMAN,Homo sapiens (Human),"apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]" comp143657_c1_seq2,685,44.5255,0.56976866,15,24,,8.00E-08,Q8BKX6,Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),GO:0005524; GO:0006281; GO:0005737; GO:0046872; GO:0000184; GO:0005634; GO:0018105; GO:0046854; GO:0046777; GO:0004674,"ATP binding; DNA repair; cytoplasm; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; phosphatidylinositol phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity",PF02260;PF00454;PF15785;,,,,,,,,,SMG1_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]" comp143658_c1_seq1,1259,37.4106,0.68677369,162,828,,3.00E-97,P57784,U2 small nuclear ribonucleoprotein A' (U2 snRNP A'),U2 small nuclear ribonucleoprotein A' (U2 snRNP A'),GO:0003723; GO:0008380; GO:0071013; GO:0006397,RNA binding; RNA splicing; catalytic step 2 spliceosome; mRNA processing,,3.00E-74,CHOYP_RU2A.1.1,,,,,,,RU2A_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp143658_c2_seq1,3212,40.2553,0.45154182,17,171,,0,Q8C079,Striatin-interacting protein 1 (Protein FAM40A),Striatin-interacting protein 1 (Protein FAM40A),GO:0030866; GO:0005737; GO:0005634; GO:0022604,cortical actin cytoskeleton organization; cytoplasm; nucleus; regulation of cell morphogenesis,PF11882;PF07923;,,,,,,,,,FA40A_MOUSE,Mus musculus (Mouse),cortical actin cytoskeleton organization [GO:0030866]; regulation of cell morphogenesis [GO:0022604] comp143658_c2_seq2,3227,40.2231,0.45003934,16,110,,,,,,,,,0,CHOYP_LOC100366965.1.2,,,,,,,,, comp143659_c2_seq7,242,45.4545,0.57447789,0,24,,,,,,,,,2.00E-17,CHOYP_DNAH6.1.3,,,,,,,,, comp143662_c0_seq1,1790,40.1676,0.64178566,12,113,,5.00E-145,O55236,mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)],mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)],GO:0006370; GO:0005525; GO:0004484; GO:0005634; GO:0035335; GO:0098507; GO:0004651; GO:0004725; GO:0008138,7-methylguanosine mRNA capping; GTP binding; mRNA guanylyltransferase activity; nucleus; peptidyl-tyrosine dephosphorylation; polynucleotide 5' dephosphorylation; polynucleotide 5'-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;PF03919;PF01331;,,,,,,,,,MCE1_MOUSE,Mus musculus (Mouse),7-methylguanosine mRNA capping [GO:0006370]; RNA processing [GO:0006396] comp143662_c0_seq3,690,45.3623,0.50971339,49,237,,1.00E-23,P24656,Tyrosine-protein phosphatase (EC 3.1.3.48) (BVP),Tyrosine-protein phosphatase (EC 3.1.3.48) (BVP),GO:0035335; GO:0004725; GO:0008138,peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,3.00E-47,CHOYP_MCE1.1.1,,,,,,,PTP_NPVAC,Autographa californica nuclear polyhedrosis virus (AcMNPV), comp143662_c0_seq4,1773,40.2143,0.64681937,31,132,,1.00E-144,O55236,mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)],mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)],GO:0006370; GO:0005525; GO:0004484; GO:0005634; GO:0035335; GO:0098507; GO:0004651; GO:0004725; GO:0008138,7-methylguanosine mRNA capping; GTP binding; mRNA guanylyltransferase activity; nucleus; peptidyl-tyrosine dephosphorylation; polynucleotide 5' dephosphorylation; polynucleotide 5'-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;PF03919;PF01331;,,,,,,,,,MCE1_MOUSE,Mus musculus (Mouse),7-methylguanosine mRNA capping [GO:0006370]; RNA processing [GO:0006396] comp143663_c0_seq4,1750,46.7429,0.64917023,177,1248,,0,Q61466,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (Protein D15KZ1) (SWI/SNF complex 60 kDa subunit),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (Protein D15KZ1) (SWI/SNF complex 60 kDa subunit),GO:0016514; GO:0048096; GO:0071565; GO:0007399; GO:0071564; GO:0006337,SWI/SNF complex; chromatin-mediated maintenance of transcription; nBAF complex; nervous system development; npBAF complex; nucleosome disassembly,PF02201;,0,CHOYP_SMRD1.1.2,,,,,,,SMRD1_MOUSE,Mus musculus (Mouse),cellular response to fatty acid [GO:0071398]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337] comp143664_c0_seq1,3145,34.9444,0.35859067,0,23,,1.00E-72,Q9DB85,Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1 homolog),Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1 homolog),GO:0016568; GO:0000183; GO:0005677; GO:0035064; GO:0008168; GO:0005730; GO:0033553; GO:0006364; GO:0006351,"chromatin modification; chromatin silencing at rDNA; chromatin silencing complex; methylated histone residue binding; methyltransferase activity; nucleolus; rDNA heterochromatin; rRNA processing; transcription, DNA-dependent",PF05148;,6.00E-38,CHOYP_LOC591283.1.1,,,,,,,RRP8_MOUSE,Mus musculus (Mouse),"cellular response to glucose starvation [GO:0042149]; chromatin modification [GO:0016568]; chromatin silencing at rDNA [GO:0000183]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of cell cycle arrest [GO:0071158]; regulation of transcription by glucose [GO:0046015]; rRNA processing [GO:0006364]; transcription, DNA-templated [GO:0006351]" comp143664_c0_seq2,3178,34.9276,0.375935,8,18,,,,,,,,,5.00E-39,CHOYP_LOC100710880.1.1,,,,,,,,, comp143665_c1_seq1,4280,39.4159,0.46181232,19,34,,1.00E-60,Q6GNY1,E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Mind bomb homolog 1),E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Mind bomb homolog 1),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB1_XENLA,Xenopus laevis (African clawed frog),Notch signaling pathway [GO:0007219] comp143665_c1_seq2,4313,39.0911,0.47234497,39,62,,1.00E-60,Q6GNY1,E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Mind bomb homolog 1),E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Mind bomb homolog 1),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB1_XENLA,Xenopus laevis (African clawed frog),Notch signaling pathway [GO:0007219] comp143666_c0_seq1,2311,43.6608,0.58025092,21,62,,0,P21127,Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1),Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1),GO:0005524; GO:0006915; GO:0008283; GO:0004693; GO:0005737; GO:0007067; GO:0005634; GO:0004674; GO:0001558; GO:0050684; GO:0006355,"ATP binding; apoptotic process; cell proliferation; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; mitosis; nucleus; protein serine/threonine kinase activity; regulation of cell growth; regulation of mRNA processing; regulation of transcription, DNA-dependent",PF00069;,0,CHOYP_CD11B.1.1,9.00E-32,ruditapes2_c2624,,,,,CD11B_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]" comp143666_c0_seq2,3258,41.8355,0.50445351,62,358,,2.00E-16,P22216,Serine/threonine-protein kinase RAD53 (EC 2.7.11.1) (CHEK2 homolog) (Serine-protein kinase 1),Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1),GO:0005524; GO:0000077; GO:0006281; GO:0006270; GO:0003688; GO:0005829; GO:0009202; GO:0005634; GO:0018108; GO:0008104; GO:0004674; GO:0004712; GO:0004713,ATP binding; DNA damage checkpoint; DNA repair; DNA replication initiation; DNA replication origin binding; cytosol; deoxyribonucleoside triphosphate biosynthetic process; nucleus; peptidyl-tyrosine phosphorylation; protein localization; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00498;PF00069;,,,,,,,,,RAD53_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; negative regulation of phosphorylation [GO:0042326]; nucleobase-containing compound metabolic process [GO:0006139]; protein localization [GO:0008104] comp143666_c0_seq3,3335,41.6192,0.49953478,72,417,,0,P21127,Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1),Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1),GO:0005524; GO:0006915; GO:0008283; GO:0004693; GO:0005737; GO:0007067; GO:0005634; GO:0004674; GO:0001558; GO:0050684; GO:0006355,"ATP binding; apoptotic process; cell proliferation; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; mitosis; nucleus; protein serine/threonine kinase activity; regulation of cell growth; regulation of mRNA processing; regulation of transcription, DNA-dependent",PF00069;,,,,,,,,,CD11B_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]" comp143668_c2_seq1,3829,38.8613,0.99767195,11724,28187,,2.00E-110,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,1.00E-16,CHOYP_LOC100646609.1.1,1.00E-12,ruditapes_c17851,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp143668_c2_seq2,1208,33.0298,1.06468974,1200,4904,,,,,,,,,,,9.00E-16,ruditapes_c17805,,,,,,, comp143669_c0_seq1,2826,41.7197,0.41215445,43,278,,0,P12955,Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase),Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase),GO:0004177; GO:0006520; GO:0030574; GO:0016805; GO:0030145; GO:0004181; GO:0006508,aminopeptidase activity; cellular amino acid metabolic process; collagen catabolic process; dipeptidase activity; manganese ion binding; metallocarboxypeptidase activity; proteolysis,PF05195;PF00557;,0,CHOYP_LOC100373864.1.2,,,,,,,PEPD_HUMAN,Homo sapiens (Human),cellular amino acid metabolic process [GO:0006520]; collagen catabolic process [GO:0030574]; proteolysis [GO:0006508] comp143669_c0_seq2,2282,41.0167,0.42566489,6,38,,3.00E-53,C4JY72,Probable Xaa-Pro aminopeptidase UREG_07123 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),Probable Xaa-Pro aminopeptidase UREG_07123 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),GO:0004177; GO:0009987; GO:0030145; GO:0008237; GO:0006508,aminopeptidase activity; cellular process; manganese ion binding; metallopeptidase activity; proteolysis,PF05195;PF00557;,1.00E-177,CHOYP_LOC100373864.1.2,,,,,,,AMPP2_UNCRE,Uncinocarpus reesii (strain UAMH 1704), comp143670_c1_seq1,2880,35.3819,0.41346159,7137,35499,,1.00E-149,P50580,Proliferation-associated protein 2G4 (IRES-specific cellular trans-acting factor 45 kDa) (ITAF45) (Mpp1) (Proliferation-associated protein 1) (Protein p38-2G4),Proliferation-associated protein 2G4 (IRES-specific cellular trans-acting factor 45 kDa) (ITAF45) (Mpp1) (Proliferation-associated protein 1) (Protein p38-2G4),GO:0003677; GO:0003723; GO:0005737; GO:0045892; GO:0005730; GO:0005634; GO:0006364; GO:0006417; GO:0030529; GO:0003700; GO:0006351,"DNA binding; RNA binding; cytoplasm; negative regulation of transcription, DNA-dependent; nucleolus; nucleus; rRNA processing; regulation of translation; ribonucleoprotein complex; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00557;,5.00E-171,CHOYP_LOC100370552.2.2,2.00E-97,ruditapes_c30403,,,,,PA2G4_MOUSE,Mus musculus (Mouse),"negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell differentiation [GO:0045597]; regulation of translation [GO:0006417]; rRNA processing [GO:0006364]; transcription, DNA-templated [GO:0006351]" comp143671_c0_seq1,2775,34.5586,0.55918732,5,77,,,,,,,,,2.00E-11,CHOYP_TRIADDRAFT_64314.2.2,,,,,,,,, comp143671_c0_seq3,2738,34.6238,0.56421884,2,84,,9.00E-09,P0AGE8,Uncharacterized protein YieF,Chromate reductase (CHRR) (EC 1.6.5.2) (NAD(P)H dehydrogenase (quinone)),GO:0016491,oxidoreductase activity,PF03358;,2.00E-11,CHOYP_TRIADDRAFT_64314.2.2,,,,,,,YIEF_SHIFL,Shigella flexneri, comp143673_c0_seq7,201,32.3383,0.1916556,5,14,,,,,,,,,,,2.00E-13,ruditapes2_c2797,,,,,,, comp143674_c0_seq1,2564,34.2044,0.56042372,7,46,,4.00E-35,Q5ZKM1,pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3),pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3),GO:0001510; GO:0008168; GO:0005730; GO:0006364,RNA methylation; methyltransferase activity; nucleolus; rRNA processing,PF11861;PF01728;PF07780;,,,,,,,,,RRMJ3_CHICK,Gallus gallus (Chicken),"enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; rRNA methylation [GO:0031167]" comp143674_c0_seq2,2609,33.9977,0.55700334,48,151,,2.00E-36,Q9DBE9,pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3),pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3),GO:0001510; GO:0008168; GO:0005730; GO:0006364,RNA methylation; methyltransferase activity; nucleolus; rRNA processing,PF11861;PF01728;PF07780;,,,,,,,,,RRMJ3_MOUSE,Mus musculus (Mouse),"enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; rRNA methylation [GO:0031167]" comp143674_c0_seq3,798,41.9799,0.42957057,114,288,,4.00E-117,Q5ZKM1,pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3),pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3),GO:0001510; GO:0008168; GO:0005730; GO:0006364,RNA methylation; methyltransferase activity; nucleolus; rRNA processing,PF11861;PF01728;PF07780;,1.00E-127,CHOYP_LOC660067.1.1,,,,,,,RRMJ3_CHICK,Gallus gallus (Chicken),"enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; rRNA methylation [GO:0031167]" comp143674_c1_seq1,804,45.8955,0.40287832,0,29,,7.00E-80,P18754,Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1),Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1),GO:0000082; GO:0005087; GO:0051301; GO:0007059; GO:0000794; GO:0005737; GO:0042393; GO:0007067; GO:0007052; GO:0000790; GO:0031965; GO:0005654; GO:0031492; GO:0007088; GO:0051225; GO:0016032,G1/S transition of mitotic cell cycle; Ran guanyl-nucleotide exchange factor activity; cell division; chromosome segregation; condensed nuclear chromosome; cytoplasm; histone binding; mitosis; mitotic spindle organization; nuclear chromatin; nuclear membrane; nucleoplasm; nucleosomal DNA binding; regulation of mitosis; spindle assembly; viral process,PF00415;,5.00E-51,CHOYP_RCC1.1.1,,,,,,,RCC1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032] comp143674_c1_seq2,2692,31.5007,0.40927057,37,48,,6.00E-13,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp143674_c1_seq3,2707,31.5109,0.40678764,38,110,,5.00E-11,Q9P2D0,Inhibitor of Bruton tyrosine kinase (IBtk),Inhibitor of Bruton tyrosine kinase (IBtk),GO:0005737; GO:0016020; GO:0005634; GO:0019901; GO:0030292; GO:0051209,cytoplasm; membrane; nucleus; protein kinase binding; protein tyrosine kinase inhibitor activity; release of sequestered calcium ion into cytosol,PF12796;PF00651;PF00415;,,,,,,,,,IBTK_HUMAN,Homo sapiens (Human),negative regulation of protein phosphorylation [GO:0001933]; release of sequestered calcium ion into cytosol [GO:0051209] comp143674_c1_seq6,819,46.398,0.55064168,23,51,,3.00E-16,Q5RCZ7,RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2),RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2),,,PF00651;PF00415;,5.00E-51,CHOYP_RCC1.1.1,,,,,,,RCBT2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp143675_c0_seq1,3153,43.4824,0.8682995,257,56,,2.00E-19,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp143675_c0_seq2,2380,44.5378,0.96090374,19,13,,9.00E-20,Q8NBH2,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_HUMAN,Homo sapiens (Human), comp143675_c0_seq3,2046,44.7703,0.98335951,22,0,,3.00E-20,Q8C8H8,Kyphoscoliosis peptidase (EC 3.4.-.-),Kyphoscoliosis peptidase (EC 3.4.-.-),GO:0030018; GO:0005856; GO:0007517; GO:0007528; GO:0008233; GO:0006508,Z disc; cytoskeleton; muscle organ development; neuromuscular junction development; peptidase activity; proteolysis,PF01841;,,,,,,,,,KY_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528] comp143677_c1_seq1,1694,39.0201,0.60520217,0,0,,2.00E-06,Q53EP0,Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),GO:0005783; GO:0016021; GO:0045600,endoplasmic reticulum; integral to membrane; positive regulation of fat cell differentiation,PF00041;,4.00E-87,CHOYP_BRAFLDRAFT_122422.1.2,,,,,,,FND3B_HUMAN,Homo sapiens (Human), comp143677_c1_seq2,2481,43.289,0.54231054,0,0,,3.00E-83,Q61191,Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],GO:0005671; GO:0071339; GO:0070688; GO:0001205; GO:0070461; GO:0048188; GO:0007049; GO:0003682; GO:0005737; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0005739; GO:0000122; GO:0043025; GO:0050821; GO:0043254; GO:0019046; GO:0003713,Ada2/Gcn5/Ada3 transcription activator complex; MLL1 complex; MLL5-L complex; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; SAGA-type complex; Set1C/COMPASS complex; cell cycle; chromatin binding; cytoplasm; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; neuronal cell body; protein stabilization; regulation of protein complex assembly; release from viral latency; transcription coactivator activity,PF01344;,4.00E-89,CHOYP_BRAFLDRAFT_122422.1.2,,,,,,,HCFC1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]" comp143677_c1_seq4,1633,39.4366,0.646361,0,0,,2.00E-06,Q53EP0,Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),GO:0005783; GO:0016021; GO:0045600,endoplasmic reticulum; integral to membrane; positive regulation of fat cell differentiation,PF00041;,,,,,,,,,FND3B_HUMAN,Homo sapiens (Human), comp143677_c1_seq5,1647,39.2835,0.61414998,0,0,,3.00E-06,Q6NWW9,Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),GO:0005783; GO:0016021; GO:0045600,endoplasmic reticulum; integral to membrane; positive regulation of fat cell differentiation,PF00041;,,,,,,,,,FND3B_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast proliferation [GO:0048146]; substrate adhesion-dependent cell spreading [GO:0034446]; Type II pneumocyte differentiation [GO:0060510] comp143677_c1_seq7,2516,43.1638,0.52928376,0,0,,4.00E-83,Q61191,Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],GO:0005671; GO:0071339; GO:0070688; GO:0001205; GO:0070461; GO:0048188; GO:0007049; GO:0003682; GO:0005737; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0005739; GO:0000122; GO:0043025; GO:0050821; GO:0043254; GO:0019046; GO:0003713,Ada2/Gcn5/Ada3 transcription activator complex; MLL1 complex; MLL5-L complex; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; SAGA-type complex; Set1C/COMPASS complex; cell cycle; chromatin binding; cytoplasm; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; neuronal cell body; protein stabilization; regulation of protein complex assembly; release from viral latency; transcription coactivator activity,PF01344;,,,,,,,,,HCFC1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]" comp143677_c1_seq9,2369,42.7607,0.55429962,8,4,,2.00E-83,Q61191,Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6],GO:0005671; GO:0071339; GO:0070688; GO:0001205; GO:0070461; GO:0048188; GO:0007049; GO:0003682; GO:0005737; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123; GO:0005739; GO:0000122; GO:0043025; GO:0050821; GO:0043254; GO:0019046; GO:0003713,Ada2/Gcn5/Ada3 transcription activator complex; MLL1 complex; MLL5-L complex; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; SAGA-type complex; Set1C/COMPASS complex; cell cycle; chromatin binding; cytoplasm; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; neuronal cell body; protein stabilization; regulation of protein complex assembly; release from viral latency; transcription coactivator activity,PF01344;,4.00E-89,CHOYP_BRAFLDRAFT_122422.1.2,,,,,,,HCFC1_MOUSE,Mus musculus (Mouse),"cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]" comp143678_c0_seq4,3717,44.848,0.50339068,16,20,,1.00E-159,A6NHR9,Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1),Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1),GO:0005524; GO:0001740; GO:0051276; GO:0060821,ATP binding; Barr body; chromosome organization; inactivation of X chromosome by DNA methylation,PF06470;,5.00E-52,CHOYP_SMHD1.1.1,,,,,,,SMHD1_HUMAN,Homo sapiens (Human),chromosome organization [GO:0051276]; inactivation of X chromosome by DNA methylation [GO:0060821] comp143678_c0_seq7,4935,44.6606,0.54582705,280,35,,0,A6NHR9,Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1),Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1),GO:0005524; GO:0001740; GO:0051276; GO:0060821,ATP binding; Barr body; chromosome organization; inactivation of X chromosome by DNA methylation,PF06470;,1.00E-43,CHOYP_BRAFLDRAFT_285500.1.1,,,,,,,SMHD1_HUMAN,Homo sapiens (Human),chromosome organization [GO:0051276]; inactivation of X chromosome by DNA methylation [GO:0060821] comp143679_c0_seq2,1476,36.5176,0.32542911,3,60,,3.00E-06,Q5U4T7,Protein bicaudal C homolog 1-B (Bic-C-B),Protein bicaudal C homolog 1-B (Bic-C-B),GO:0003723; GO:0007275,RNA binding; multicellular organismal development,PF00013;PF00536;,,,,,,,,,BIC1B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275] comp143679_c0_seq4,1909,41.121,0.32693861,2,17,,1.00E-52,Q07DZ7,"Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)","Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)",GO:0043046; GO:0030154; GO:0031047; GO:0007140; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; cell differentiation; gene silencing by RNA; male meiosis; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF12796;PF00536;,2.00E-22,CHOYP_NEMVEDRAFT_V1G199674.1.1,,,,,,,ASZ1_ORNAN,Ornithorhynchus anatinus (Duckbill platypus),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp143679_c0_seq5,2299,38.495,0.36721163,0,19,,3.00E-52,Q07DZ7,"Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)","Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)",GO:0043046; GO:0030154; GO:0031047; GO:0007140; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; cell differentiation; gene silencing by RNA; male meiosis; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF12796;PF00536;,,,,,,,,,ASZ1_ORNAN,Ornithorhynchus anatinus (Duckbill platypus),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp143680_c0_seq1,5389,40.3785,0.47758286,0,0,,0,Q8BKF1,"DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)","DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)",GO:0003677; GO:0003899; GO:0005739; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; mitochondrion; transcription, DNA-dependent",PF00940;PF14700;,1.00E-29,CHOYP_LOC100024662.1.1,,,,,,,RPOM_MOUSE,Mus musculus (Mouse),transcription from mitochondrial promoter [GO:0006390] comp143680_c0_seq10,5443,40.4189,0.4759633,0,0,,9.00E-124,Q8L6J3,"DNA-directed RNA polymerase 2B, chloroplastic/mitochondrial (EC 2.7.7.6) (NictaRpoT2-tom) (T7 bacteriophage-type single subunit RNA polymerase 2B)","DNA-directed RNA polymerase 2B, chloroplastic/mitochondrial (EC 2.7.7.6) (NictaRpoT2-tom) (T7 bacteriophage-type single subunit RNA polymerase 2B)",GO:0003677; GO:0003899; GO:0009507; GO:0005739; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; chloroplast; mitochondrion; transcription, DNA-dependent",PF00940;PF14700;,,,,,,,,,RPO2B_TOBAC,Nicotiana tabacum (Common tobacco),"transcription, DNA-templated [GO:0006351]" comp143680_c0_seq12,5363,40.3692,0.48012147,0,0,,0,Q8BKF1,"DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)","DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)",GO:0003677; GO:0003899; GO:0005739; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; mitochondrion; transcription, DNA-dependent",PF00940;PF14700;,1.00E-29,CHOYP_LOC100024662.1.1,,,,,,,RPOM_MOUSE,Mus musculus (Mouse),transcription from mitochondrial promoter [GO:0006390] comp143680_c0_seq13,5417,40.4283,0.47805884,0,0,,,,,,,,,1.00E-29,CHOYP_LOC100024662.1.1,,,,,,,,, comp143680_c0_seq14,3655,38.9877,0.49869333,0,0,,1.00E-54,O00411,"DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)","DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)",GO:0003677; GO:0003899; GO:0042645; GO:0006391,DNA binding; DNA-directed RNA polymerase activity; mitochondrial nucleoid; transcription initiation from mitochondrial promoter,PF00940;PF14700;,,,,,,,,,RPOM_HUMAN,Homo sapiens (Human),mitochondrion organization [GO:0007005]; transcription from mitochondrial promoter [GO:0006390]; transcription initiation from mitochondrial promoter [GO:0006391] comp143680_c0_seq15,577,40.0347,0.43841151,0,0,,2.00E-31,Q8L6J4,DNA-directed RNA polymerase 1A (EC 2.7.7.6) (NictaRpoT1-syl) (T7 bacteriophage-type single subunit RNA polymerase 1A) (Fragment),DNA-directed RNA polymerase 1A (EC 2.7.7.6) (NictaRpoT1-syl) (T7 bacteriophage-type single subunit RNA polymerase 1A) (Fragment),GO:0003677; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF00940;,,,,,,,,,RPO1A_TOBAC,Nicotiana tabacum (Common tobacco),"transcription, DNA-templated [GO:0006351]" comp143680_c0_seq2,5336,40.3673,0.47339794,7,0,,8.00E-130,Q8L6J3,"DNA-directed RNA polymerase 2B, chloroplastic/mitochondrial (EC 2.7.7.6) (NictaRpoT2-tom) (T7 bacteriophage-type single subunit RNA polymerase 2B)","DNA-directed RNA polymerase 2B, chloroplastic/mitochondrial (EC 2.7.7.6) (NictaRpoT2-tom) (T7 bacteriophage-type single subunit RNA polymerase 2B)",GO:0003677; GO:0003899; GO:0009507; GO:0005739; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; chloroplast; mitochondrion; transcription, DNA-dependent",PF00940;PF14700;,1.00E-29,CHOYP_LOC100024662.1.1,,,,,,,RPO2B_TOBAC,Nicotiana tabacum (Common tobacco),"transcription, DNA-templated [GO:0006351]" comp143680_c0_seq3,5470,40.3839,0.47436809,0,0,,0,Q8BKF1,"DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)","DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)",GO:0003677; GO:0003899; GO:0005739; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; mitochondrion; transcription, DNA-dependent",PF00940;PF14700;,,,,,,,,,RPOM_MOUSE,Mus musculus (Mouse),transcription from mitochondrial promoter [GO:0006390] comp143680_c0_seq7,5362,40.3954,0.47962619,0,0,,0,O00411,"DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)","DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)",GO:0003677; GO:0003899; GO:0042645; GO:0006391,DNA binding; DNA-directed RNA polymerase activity; mitochondrial nucleoid; transcription initiation from mitochondrial promoter,PF00940;PF14700;,1.00E-29,CHOYP_LOC100024662.1.1,,,,,,,RPOM_HUMAN,Homo sapiens (Human),mitochondrion organization [GO:0007005]; transcription from mitochondrial promoter [GO:0006390]; transcription initiation from mitochondrial promoter [GO:0006391] comp143680_c0_seq9,5444,40.4298,0.47565269,0,0,,0,Q8BKF1,"DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)","DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)",GO:0003677; GO:0003899; GO:0005739; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; mitochondrion; transcription, DNA-dependent",PF00940;PF14700;,1.00E-29,CHOYP_LOC100024662.1.1,,,,,,,RPOM_MOUSE,Mus musculus (Mouse),transcription from mitochondrial promoter [GO:0006390] comp143682_c0_seq1,4058,35.5101,0.37104544,1118,180,,1.00E-132,Q99P25,Translin-associated factor X-interacting protein 1 (Trax-interacting protein 1),Translin-associated factor X-interacting protein 1 (Trax-interacting protein 1),GO:0030154; GO:0005737; GO:0007275; GO:0048471; GO:0007283,cell differentiation; cytoplasm; multicellular organismal development; perinuclear region of cytoplasm; spermatogenesis,PF15739;,6.00E-147,CHOYP_BRAFLDRAFT_117631.1.1,,,,,,,TXIP1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp143682_c1_seq1,1087,41.9503,0.54928202,92,693,,3.00E-120,Q7YRA3,Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41),Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41),GO:0017091; GO:0045006; GO:0005737; GO:0051607; GO:0004527; GO:0000178; GO:0071044; GO:0000460; GO:0071028; GO:0090305; GO:0005730; GO:0030307; GO:0035327,AU-rich element binding; DNA deamination; cytoplasm; defense response to virus; exonuclease activity; exosome (RNase complex); histone mRNA catabolic process; maturation of 5.8S rRNA; nuclear mRNA surveillance; nucleic acid phosphodiester bond hydrolysis; nucleolus; positive regulation of cell growth; transcriptionally active chromatin,PF01138;PF03725;,4.00E-117,CHOYP_LOC100368480.1.1,0,ruditapes_c9146,,,,,EXOS4_BOVIN,Bos taurus (Bovine),"defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475]" comp143684_c0_seq1,3264,35.5699,0.43691533,4,139,,,,,,,,,0,CHOYP_CEBPZ.1.1,,,,,,,,, comp143684_c0_seq2,3028,35.7001,0.46745756,29,41,,4.00E-22,O28579,Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS),Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS),GO:0005524; GO:0005737; GO:0004830; GO:0006436,ATP binding; cytoplasm; tryptophan-tRNA ligase activity; tryptophanyl-tRNA aminoacylation,PF00579;,,,,,,,,,SYW_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126),tryptophanyl-tRNA aminoacylation [GO:0006436] comp143684_c0_seq3,3299,35.3744,0.4370604,7,153,,0,P17248,"Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) [Cleaved into: T1-TrpRS; T2-TrpRS]","Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) [Cleaved into: T1-TrpRS; T2-TrpRS]",GO:0005524; GO:0005737; GO:0045765; GO:0004830; GO:0006436,ATP binding; cytoplasm; regulation of angiogenesis; tryptophan-tRNA ligase activity; tryptophanyl-tRNA aminoacylation,PF00579;PF00458;,,,,,,,,,SYWC_BOVIN,Bos taurus (Bovine),regulation of angiogenesis [GO:0045765]; tryptophanyl-tRNA aminoacylation [GO:0006436] comp143684_c0_seq4,2993,35.9171,0.46723824,1,138,,,,,,,,,3.00E-180,CHOYP_SYWC.1.5,,,,,,,,, comp143684_c0_seq5,3016,35.809,0.46643264,0,0,,4.00E-22,O28579,Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS),Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS),GO:0005524; GO:0005737; GO:0004830; GO:0006436,ATP binding; cytoplasm; tryptophan-tRNA ligase activity; tryptophanyl-tRNA aminoacylation,PF00579;,0,CHOYP_CEBPZ.1.1,,,,,,,SYW_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126),tryptophanyl-tRNA aminoacylation [GO:0006436] comp143684_c0_seq6,3287,35.4731,0.43618615,0,0,,0,P17248,"Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) [Cleaved into: T1-TrpRS; T2-TrpRS]","Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) [Cleaved into: T1-TrpRS; T2-TrpRS]",GO:0005524; GO:0005737; GO:0045765; GO:0004830; GO:0006436,ATP binding; cytoplasm; regulation of angiogenesis; tryptophan-tRNA ligase activity; tryptophanyl-tRNA aminoacylation,PF00579;PF00458;,0,CHOYP_CEBPZ.1.1,,,,,,,SYWC_BOVIN,Bos taurus (Bovine),regulation of angiogenesis [GO:0045765]; tryptophanyl-tRNA aminoacylation [GO:0006436] comp143685_c0_seq1,4741,44.1046,0.6085011,788,7664,,0,Q12873,Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH),Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH),GO:0005524; GO:0004003; GO:0003677; GO:0016581; GO:0005813; GO:0051297; GO:0006333; GO:0016568; GO:0005737; GO:0045111; GO:0005730; GO:0006357; GO:0007051; GO:0006351; GO:0008270,"ATP binding; ATP-dependent DNA helicase activity; DNA binding; NuRD complex; centrosome; centrosome organization; chromatin assembly or disassembly; chromatin modification; cytoplasm; intermediate filament cytoskeleton; nucleolus; regulation of transcription from RNA polymerase II promoter; spindle organization; transcription, DNA-dependent; zinc ion binding",PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;,0,CHOYP_CHD5.2.2,,,,,,,CHD3_HUMAN,Homo sapiens (Human),"centrosome organization [GO:0051297]; chromatin assembly or disassembly [GO:0006333]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle organization [GO:0007051]; transcription, DNA-templated [GO:0006351]" comp143686_c0_seq1,2143,42.7438,0.46853157,1,28,,,,,,,,,0,CHOYP_NELFD.1.1,,,,,,,,, comp143686_c0_seq3,3343,39.0069,0.41979406,1,27,,0,A5GFY4,Negative elongation factor D (NELF-D) (TH1-like protein),Negative elongation factor D (NELF-D) (TH1-like protein),GO:0032021; GO:0045892; GO:0006351,"NELF complex; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04858;,,,,,,,,,NELFD_PIG,Sus scrofa (Pig),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp143687_c1_seq2,277,47.2924,0.72623726,60,87,,4.00E-32,Q02427,RNA-binding protein 1,RNA-binding protein 1,GO:0003729; GO:0045292; GO:0006376; GO:0000166; GO:0005634; GO:0035327,"mRNA binding; mRNA cis splicing, via spliceosome; mRNA splice site selection; nucleotide binding; nucleus; transcriptionally active chromatin",PF00076;,6.00E-38,CHOYP_RBP1.2.2,7.00E-16,ruditapes_c10863,,,,,RBP1_DROME,Drosophila melanogaster (Fruit fly),"mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380]" comp143690_c0_seq1,4012,44.2921,0.42101589,1194,6916,,0,Q6P5B0,RRP12-like protein,RRP12-like protein,GO:0016021; GO:0031965; GO:0005730,integral to membrane; nuclear membrane; nucleolus,PF08161;,0,CHOYP_LOC100377837.2.2,7.00E-23,ruditapes_c26517,,,,,RRP12_MOUSE,Mus musculus (Mouse), comp143691_c0_seq1,1339,46.9754,0.65030165,147,29,,2.00E-25,Q60974,Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) (Retinoid X receptor-interacting protein 13) (RIP13),Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) (Retinoid X receptor-interacting protein 13) (RIP13),GO:0002361; GO:0042632; GO:0003682; GO:0016568; GO:0032922; GO:0005829; GO:0060318; GO:0035033; GO:0014067; GO:0000122; GO:0031065; GO:0040014; GO:0046965; GO:0043565; GO:0003700; GO:0021794; GO:0046966; GO:0003714; GO:0005667; GO:0044212; GO:0006351; GO:0017053,"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; cholesterol homeostasis; chromatin binding; chromatin modification; circadian regulation of gene expression; cytosol; definitive erythrocyte differentiation; histone deacetylase regulator activity; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone deacetylation; regulation of multicellular organism growth; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; thalamus development; thyroid hormone receptor binding; transcription corepressor activity; transcription factor complex; transcription regulatory region DNA binding; transcription, DNA-dependent; transcriptional repressor complex",PF15784;PF00249;,3.00E-50,CHOYP_LOC588549.2.2,,,,,,,NCOR1_MOUSE,Mus musculus (Mouse),"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cholesterol homeostasis [GO:0042632]; chromatin modification [GO:0016568]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; definitive erythrocyte differentiation [GO:0060318]; negative regulation of JNK cascade [GO:0046329]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072362]; regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter [GO:0072368]; regulation of multicellular organism growth [GO:0040014]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle assembly [GO:0051225]; thalamus development [GO:0021794]; transcription, DNA-templated [GO:0006351]" comp143692_c0_seq1,2856,37.7451,0.50741238,5,0,,9.00E-77,P45962,Kinesin-like protein klp-3,Kinesin-like protein klp-3,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,4.00E-14,CHOYP_LOC373208.1.1,,,,,,,KLP3_CAEEL,Caenorhabditis elegans,cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; neurogenesis [GO:0022008] comp143692_c0_seq3,2857,37.9419,0.52160475,13,52,,7.00E-140,P79955,Carboxy-terminal kinesin 2 (XCTK2),Carboxy-terminal kinesin 2 (XCTK2),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,6.00E-107,CHOYP_KLPA.1.1,,,,,,,CTK2_XENLA,Xenopus laevis (African clawed frog),microtubule-based movement [GO:0007018] comp143693_c0_seq1,1408,46.875,0.47879419,207,1236,,0,P53620,Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP),Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP),GO:0030126; GO:0006891; GO:0006886; GO:0005634; GO:0006890; GO:0005198,"COPI vesicle coat; intra-Golgi vesicle-mediated transport; intracellular protein transport; nucleus; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",PF01602;PF16381;PF08752;,0,CHOYP_COPG2.1.1,,,,,,,COPG1_BOVIN,Bos taurus (Bovine),"intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp143693_c1_seq1,1848,42.0455,0.48202554,722,5085,,0,Q9PUE4,Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP),Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP),GO:0030126; GO:0006886; GO:0005198; GO:0016192,COPI vesicle coat; intracellular protein transport; structural molecule activity; vesicle-mediated transport,PF01602;PF16381;PF08752;,,,1.00E-92,ruditapes_c22512,,,,,COPG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp143694_c1_seq2,1753,36.9652,0.51893508,76,105,,8.00E-68,Q3UJZ3,Armadillo repeat-containing protein 7,Armadillo repeat-containing protein 7,,,PF00514;,4.00E-49,CHOYP_BRAFLDRAFT_100948.1.1,,,,,,,ARMC7_MOUSE,Mus musculus (Mouse), comp143695_c0_seq2,2029,33.514,0.54454688,23,28,,2.00E-20,Q9DAR0,Uncharacterized protein C5orf49 homolog (Y regulated sperm protein),Uncharacterized protein C5orf49 homolog (Y regulated sperm protein),,,PF15074;,5.00E-11,CHOYP_LOC100369902.1.1,,,,,,,CE049_MOUSE,Mus musculus (Mouse), comp143696_c1_seq1,3915,38.3397,0.49592581,1537,253,,,,,,,,,3.00E-99,CHOYP_LOC582005.1.1,,,,,,,,, comp143696_c3_seq2,376,44.4149,0.9232275,5,66,,2.00E-10,P51749,"CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (CD antigen CD154) [Cleaved into: CD40 ligand, membrane form; CD40 ligand, soluble form]","CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (CD antigen CD154) [Cleaved into: CD40 ligand, membrane form; CD40 ligand, soluble form]",GO:0042100; GO:0005174; GO:0005615; GO:0006955; GO:0006954; GO:0016021; GO:0005886; GO:0030168,B cell proliferation; CD40 receptor binding; extracellular space; immune response; inflammatory response; integral to membrane; plasma membrane; platelet activation,PF00229;,,,,,,,,,CD40L_BOVIN,Bos taurus (Bovine),activation of JUN kinase activity [GO:0007257]; B cell proliferation [GO:0042100]; immune response [GO:0006955]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102] comp143696_c3_seq3,523,46.0803,0.97438373,25,14,,3.00E-20,P50592,Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253),Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253),GO:0005615; GO:0006955; GO:0016021; GO:0043123; GO:0043065; GO:0043280; GO:2001238; GO:0090200,extracellular space; immune response; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of release of cytochrome c from mitochondria,PF00229;,,,,,,,,,TNF10_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; immune response [GO:0006955]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of release of cytochrome c from mitochondria [GO:0090200] comp143699_c0_seq1,1490,46.443,0.4029051,0,10,,9.00E-13,A8M4V8,Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha (ACCase subunits beta/alpha) (Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha) (EC 6.4.1.2),Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha (ACCase subunits beta/alpha) (Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha) (EC 6.4.1.2),GO:0005524; GO:0003989; GO:0009317; GO:0006633; GO:2001295; GO:0046872,ATP binding; acetyl-CoA carboxylase activity; acetyl-CoA carboxylase complex; fatty acid biosynthetic process; malonyl-CoA biosynthetic process; metal ion binding,PF03255;PF01039;,,,,,,,,,ACCDA_SALAI,Salinispora arenicola (strain CNS-205),fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295] comp143699_c0_seq3,2286,40.5949,0.39884529,104,399,,0,P79384,"Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)","Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)",GO:0005524; GO:0005759; GO:0004658,ATP binding; mitochondrial matrix; propionyl-CoA carboxylase activity,PF01039;,0,CHOYP_PCCB.2.2,,,,,,,PCCB_PIG,Sus scrofa (Pig), comp143700_c0_seq1,2241,44.5337,0.47026374,16,0,,4.00E-18,Q8CDL9,Coiled-coil domain-containing protein 87,Coiled-coil domain-containing protein 87,GO:0000910; GO:0000226,cytokinesis; microtubule cytoskeleton organization,,,,,,,,,,CCD87_MOUSE,Mus musculus (Mouse), comp143700_c0_seq2,1755,43.7607,0.45415765,0,0,,,,,,,,,2.00E-79,CHOYP_LOC100376463.1.1,,,,,,,,, comp143700_c1_seq1,2435,36.386,0.53620964,72,156,,1.00E-19,Q8CDL9,Coiled-coil domain-containing protein 87,Coiled-coil domain-containing protein 87,GO:0000910; GO:0000226,cytokinesis; microtubule cytoskeleton organization,,,,,,,,,,CCD87_MOUSE,Mus musculus (Mouse), comp143700_c1_seq2,2134,37.582,0.54017482,107,114,,1.00E-21,Q9NVE4,Coiled-coil domain-containing protein 87,Coiled-coil domain-containing protein 87,GO:0000910; GO:0000226,cytokinesis; microtubule cytoskeleton organization,,1.00E-62,CHOYP_LOC100376463.1.1,,,,,,,CCD87_HUMAN,Homo sapiens (Human), comp143701_c0_seq2,2382,41.4358,0.65632053,848,4126,,0,Q8WUQ7,Cactin (Renal carcinoma antigen NY-REN-24),Cactin (Renal carcinoma antigen NY-REN-24),GO:0071013; GO:0071347; GO:0071222; GO:0071356; GO:0045087; GO:0000398; GO:0007275; GO:0032088; GO:0032688; GO:0032717; GO:0031665; GO:0001933; GO:0034122; GO:0032720; GO:0060339,"catalytic step 2 spliceosome; cellular response to interleukin-1; cellular response to lipopolysaccharide; cellular response to tumor necrosis factor; innate immune response; mRNA splicing, via spliceosome; multicellular organismal development; negative regulation of NF-kappaB transcription factor activity; negative regulation of interferon-beta production; negative regulation of interleukin-8 production; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of protein phosphorylation; negative regulation of toll-like receptor signaling pathway; negative regulation of tumor necrosis factor production; negative regulation of type I interferon-mediated signaling pathway",PF10312;PF09732;,2.00E-100,CHOYP_CATIN.1.1,,,,,,,CATIN_HUMAN,Homo sapiens (Human),"cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; innate immune response [GO:0045087]; mRNA splicing, via spliceosome [GO:0000398]; multicellular organism development [GO:0007275]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]" comp143702_c0_seq1,1652,35.5327,0.55847217,77,508,,1.00E-10,Q4V832,AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Tetra-epsin),AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Tetra-epsin),,,PF01417;,,,,,,,,,AP4AT_XENLA,Xenopus laevis (African clawed frog), comp143702_c0_seq7,835,43.2335,0.38539609,2,0,,5.00E-35,Q96N21,AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Epsin for AP-4) (Tetra-epsin),AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Epsin for AP-4) (Tetra-epsin),GO:0016023; GO:0005829,cytoplasmic membrane-bounded vesicle; cytosol,PF01417;,,,,,,,,,AP4AT_HUMAN,Homo sapiens (Human), comp143702_c0_seq9,1730,34.9133,0.38602647,0,0,,,,,,,,,,,5.00E-14,ruditapes_c23502,,,,,,, comp143703_c0_seq1,951,39.1167,0.64981078,103,625,,3.00E-82,Q9Y3C6,Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1),Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1),GO:0071013; GO:0000398; GO:0003755; GO:0006457; GO:0000413,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization",PF00160;,1.00E-72,CHOYP_CYPL.1.1,2.00E-99,ruditapes2_c1116,,,,,PPIL1_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]" comp143703_c0_seq4,1451,39.6278,0.33384981,39,252,,5.00E-45,Q3SYZ9,Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4),Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4),GO:0001104; GO:0030521; GO:0016592; GO:0045893; GO:0004872; GO:0006367,"RNA polymerase II transcription cofactor activity; androgen receptor signaling pathway; mediator complex; positive regulation of transcription, DNA-dependent; receptor activity; transcription initiation from RNA polymerase II promoter",PF10018;,2.00E-27,CHOYP_MED4.1.1,,,,,,,MED4_BOVIN,Bos taurus (Bovine),"androgen receptor signaling pathway [GO:0030521]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp143703_c0_seq6,567,39.8589,0.31226045,0,28,,2.00E-43,Q7QH62,Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4),Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF10018;,,,,,,,,,MED4_ANOGA,Anopheles gambiae (African malaria mosquito),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143706_c0_seq1,2309,39.1511,0.46390095,16,18,,1.00E-131,Q8IUR7,Armadillo repeat-containing protein 8,Armadillo repeat-containing protein 8,,,PF00514;,1.00E-113,CHOYP_BRAFLDRAFT_123389.1.1,,,,,,,ARMC8_HUMAN,Homo sapiens (Human), comp143706_c0_seq2,2327,39.1491,0.46043868,5,48,,4.00E-129,Q8IUR7,Armadillo repeat-containing protein 8,Armadillo repeat-containing protein 8,,,PF00514;,,,,,,,,,ARMC8_HUMAN,Homo sapiens (Human), comp143707_c0_seq1,3158,32.6472,0.48592529,1983,5299,,6.00E-74,Q9CQE6,Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A),Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A),GO:0006281; GO:0016568; GO:0042692; GO:0006334; GO:0005634; GO:0001649; GO:0006355; GO:0006351,"DNA repair; chromatin modification; muscle cell differentiation; nucleosome assembly; nucleus; osteoblast differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04729;,1.00E-77,CHOYP_ISCW_ISCW013556.1.1,,,8.00E-80,AM856942.p.cg.6,8,,ASF1A_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; DNA repair [GO:0006281]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; muscle cell differentiation [GO:0042692]; nucleosome assembly [GO:0006334]; osteoblast differentiation [GO:0001649]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143708_c0_seq2,1347,30.5122,0.35538319,176,784,,8.00E-12,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143710_c0_seq11,930,39.3548,0.74013233,121,71,,4.00E-62,Q02224,Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE),Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE),GO:0005524; GO:0019886; GO:0007596; GO:0051301; GO:0000940; GO:0000779; GO:0000778; GO:0005829; GO:0005871; GO:0000776; GO:0051382; GO:0043515; GO:0005874; GO:0003777; GO:0007079; GO:0000089; GO:0007080; GO:0007094; GO:0007275; GO:0005634; GO:0045860; GO:0051233,"ATP binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; cell division; condensed chromosome outer kinetochore; condensed chromosome, centromeric region; condensed nuclear chromosome kinetochore; cytosol; kinesin complex; kinetochore; kinetochore assembly; kinetochore binding; microtubule; microtubule motor activity; mitotic chromosome movement towards spindle pole; mitotic metaphase; mitotic metaphase plate congression; mitotic spindle assembly checkpoint; multicellular organismal development; nucleus; positive regulation of protein kinase activity; spindle midzone",PF00225;,2.00E-37,CHOYP_LOC576192.1.1,,,,,,,CENPE_HUMAN,Homo sapiens (Human),"antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; multicellular organism development [GO:0007275]; positive regulation of protein kinase activity [GO:0045860]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; sister chromatid cohesion [GO:0007062]" comp143711_c0_seq1,2683,46.9624,0.62417982,27,4,,,,,,,,,,,4.00E-24,ruditapes_c13688,,,,,,, comp143711_c0_seq2,5373,47.4223,0.6359011,333,63,,2.00E-37,Q9C0D2,Centrosomal protein KIAA1731,Centrosomal protein of 295 kDa,GO:0005813; GO:0005737,centrosome; cytoplasm,PF15309;,9.00E-32,CHOYP_LOC763378.1.1,,,,,,,K1731_HUMAN,Homo sapiens (Human),positive regulation of organelle assembly [GO:1902117] comp143713_c0_seq3,4756,40.5593,0.51668712,212,995,,2.00E-11,Q8MIB8,"Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X)","Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X)",GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF05920;,3.00E-119,CHOYP_BRAFLDRAFT_123978.1.1,,,,,,,TF2LX_PONPY,Pongo pygmaeus (Bornean orangutan),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143716_c0_seq1,1800,39.9444,0.48608809,171,982,,1.00E-47,Q7TQ20,DnaJ homolog subfamily C member 2 (Gliosarcoma-related antigen MIDA1) (Zuotin-related factor 1),"DnaJ homolog subfamily C member 2 (Gliosarcoma-related antigen MIDA1) (Zuotin-related factor 1) [Cleaved into: DnaJ homolog subfamily C member 2, N-terminally processed]",GO:0003677; GO:0003682; GO:0016568; GO:0005829; GO:0042393; GO:0030308; GO:0031965; GO:0005634; GO:0045893; GO:0006351; GO:0043130,"DNA binding; chromatin binding; chromatin modification; cytosol; histone binding; negative regulation of cell growth; nuclear membrane; nucleus; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin binding",PF00226;PF00249;PF16717;,2.00E-135,CHOYP_DNJC2.1.1,5.00E-91,ruditapes_c29332,,,,,DNJC2_RAT,Rattus norvegicus (Rat),"chromatin modification [GO:0016568]; negative regulation of cell growth [GO:0030308]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp143717_c1_seq1,2308,38.3882,0.61243511,107,499,,0,Q9V3J1,V-type proton ATPase subunit H (V-ATPase subunit H) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD),V-type proton ATPase subunit H (V-ATPase subunit H) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD),GO:0015991; GO:0008340; GO:0033227; GO:0033181; GO:0046961; GO:0000221,"ATP hydrolysis coupled proton transport; determination of adult lifespan; dsRNA transport; plasma membrane proton-transporting V-type ATPase complex; proton-transporting ATPase activity, rotational mechanism; vacuolar proton-transporting V-type ATPase, V1 domain",PF11698;,2.00E-176,CHOYP_LOC100648051.1.2,4.00E-99,ruditapes_c22123,,,,,VATH_DROME,Drosophila melanogaster (Fruit fly),ATP hydrolysis coupled proton transport [GO:0015991]; determination of adult lifespan [GO:0008340]; dsRNA transport [GO:0033227] comp143717_c2_seq1,258,39.1473,0.40659951,4,18,,8.00E-10,O46563,V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD),V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD),GO:0015991; GO:0046961; GO:0000221,"ATP hydrolysis coupled proton transport; proton-transporting ATPase activity, rotational mechanism; vacuolar proton-transporting V-type ATPase, V1 domain",PF11698;,,,,,,,,,VATH_BOVIN,Bos taurus (Bovine),ATP hydrolysis coupled proton transport [GO:0015991] comp143718_c0_seq1,1351,41.6728,0.44887143,0,0,,3.00E-130,Q0IHQ8,Serine/threonine-protein kinase 10 (EC 2.7.11.1),Serine/threonine-protein kinase 10 (EC 2.7.11.1),GO:0005524; GO:0007049; GO:0005886; GO:0046777; GO:0042803; GO:0004674; GO:2000401,ATP binding; cell cycle; plasma membrane; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; regulation of lymphocyte migration,PF00069;PF12474;,2.00E-13,CHOYP_LOC100864577.1.1,,,,,,,STK10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; protein autophosphorylation [GO:0046777]; regulation of lymphocyte migration [GO:2000401] comp143718_c0_seq2,4015,43.2628,0.54134207,533,394,,6.00E-123,E1BK52,Serine/threonine-protein kinase 10 (EC 2.7.11.1),Serine/threonine-protein kinase 10 (EC 2.7.11.1),GO:0005524; GO:0007049; GO:0071593; GO:0005886; GO:0046777; GO:0042803; GO:0004674; GO:2000401,ATP binding; cell cycle; lymphocyte aggregation; plasma membrane; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; regulation of lymphocyte migration,PF00069;PF12474;,0,CHOYP_SLK.1.1,2.00E-30,ruditapes_c14587,,,,,STK10_BOVIN,Bos taurus (Bovine),cell cycle [GO:0007049]; protein autophosphorylation [GO:0046777]; regulation of lymphocyte migration [GO:2000401] comp143722_c0_seq1,1808,33.0752,0.38695199,0,21,,,,,,,,,2.00E-72,CHOYP_VATE.1.1,,,,,,,,, comp143722_c0_seq2,2909,31.8666,0.4358694,429,3377,,1.00E-85,P54611,V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E),V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E),GO:0015991; GO:0033181; GO:0046961; GO:0000221,"ATP hydrolysis coupled proton transport; plasma membrane proton-transporting V-type ATPase complex; proton-transporting ATPase activity, rotational mechanism; vacuolar proton-transporting V-type ATPase, V1 domain",PF01991;,3.00E-72,CHOYP_VATE.1.1,2.00E-66,ruditapes_c433,,,,,VATE_DROME,Drosophila melanogaster (Fruit fly),"apical protein localization [GO:0045176]; ATP hydrolysis coupled proton transport [GO:0015991]; proton transport [GO:0015992]; terminal branching, open tracheal system [GO:0007430]; trachea morphogenesis [GO:0060439]" comp143723_c0_seq1,1361,34.5334,0.40962428,18,85,,4.00E-45,P58281,"Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Large GTP-binding protein) (LargeG) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]","Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Large GTP-binding protein) (LargeG) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]",GO:0005525; GO:0003924; GO:0006915; GO:0030425; GO:0007007; GO:0016021; GO:0030061; GO:0008053; GO:0005758; GO:0005741; GO:2001243; GO:0090201; GO:0001843; GO:0050896; GO:0007601,GTP binding; GTPase activity; apoptotic process; dendrite; inner mitochondrial membrane organization; integral to membrane; mitochondrial crista; mitochondrial fusion; mitochondrial intermembrane space; mitochondrial outer membrane; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of release of cytochrome c from mitochondria; neural tube closure; response to stimulus; visual perception,PF00350;,,,,,,,,,OPA1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cellular senescence [GO:0090398]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053]; mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; neural tube closure [GO:0001843]; visual perception [GO:0007601] comp143723_c0_seq10,2753,42.3175,0.43091594,0,0,,0,Q5U3A7,"Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]","Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]",GO:0005525; GO:0006184; GO:0003924; GO:0006915; GO:0009790; GO:0016021; GO:0008053; GO:0005743; GO:0005758; GO:0070584,GTP binding; GTP catabolic process; GTPase activity; apoptotic process; embryo development; integral to membrane; mitochondrial fusion; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion morphogenesis,PF00350;,0,CHOYP_LOC100877393.1.1,,,,,,,OPA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; chordate embryonic development [GO:0043009]; mitochondrion morphogenesis [GO:0070584] comp143723_c0_seq4,2698,43.0319,0.42709861,0,0,,3.00E-28,P54861,Dynamin-related protein DNM1 (EC 3.6.5.5),Dynamin-related protein DNM1 (EC 3.6.5.5),GO:0005525; GO:0003924; GO:0001300; GO:0000266; GO:0005741; GO:0000001; GO:0005777; GO:0016559; GO:0042803; GO:0051260,GTP binding; GTPase activity; chronological cell aging; mitochondrial fission; mitochondrial outer membrane; mitochondrion inheritance; peroxisome; peroxisome fission; protein homodimerization activity; protein homooligomerization,PF01031;PF00350;PF02212;,,,,,,,,,DNM1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),chronological cell aging [GO:0001300]; macroautophagy [GO:0016236]; mitochondrial fission [GO:0000266]; mitochondrion inheritance [GO:0000001]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; protein homooligomerization [GO:0051260] comp143723_c0_seq6,2656,42.9217,0.4186481,0,0,,0,Q5U3A7,"Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]","Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]",GO:0005525; GO:0006184; GO:0003924; GO:0006915; GO:0009790; GO:0016021; GO:0008053; GO:0005743; GO:0005758; GO:0070584,GTP binding; GTP catabolic process; GTPase activity; apoptotic process; embryo development; integral to membrane; mitochondrial fusion; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion morphogenesis,PF00350;,0,CHOYP_LOC100877393.1.1,,,,,,,OPA1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; chordate embryonic development [GO:0043009]; mitochondrion morphogenesis [GO:0070584] comp143723_c0_seq7,1205,41.1618,0.40264451,0,0,,,,,,,,,2.00E-139,CHOYP_LOC100877393.1.1,,,,,,,,, comp143726_c0_seq4,2954,40.9276,0.3882964,281,626,,1.00E-49,O54714,E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (Protein inhibitor of activated STAT protein 3),E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (Protein inhibitor of activated STAT protein 3),GO:0019789; GO:0005737; GO:0030425; GO:0003676; GO:0005634; GO:0010628; GO:0045838; GO:0033235; GO:0015459; GO:0016925; GO:0006355; GO:0009725; GO:0045202; GO:0006351; GO:0008270,"SUMO ligase activity; cytoplasm; dendrite; nucleic acid binding; nucleus; positive regulation of gene expression; positive regulation of membrane potential; positive regulation of protein sumoylation; potassium channel regulator activity; protein sumoylation; regulation of transcription, DNA-dependent; response to hormone stimulus; synapse; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS3_MOUSE,Mus musculus (Mouse),"negative regulation of protein sumoylation [GO:0033234]; positive regulation of gene expression [GO:0010628]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of transcription, DNA-templated [GO:0006355]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp143730_c0_seq4,516,37.2093,1.00976942,13,95,,1.00E-11,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp143732_c0_seq1,4405,41.9523,0.54456153,86,186,,0,A2A4P0,ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8),ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0071013; GO:0006397,ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; catalytic step 2 spliceosome; mRNA processing,PF04408;PF00271;PF07717;PF00575;,0,CHOYP_DHX8.2.3,,,,,,,DHX8_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp143732_c0_seq2,4398,41.8145,0.5272368,52,178,,0,Q09530,Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 (EC 3.6.4.13) (Masculinization of germline protein 5) (Sex determination protein mog-5),Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 (EC 3.6.4.13) (Masculinization of germline protein 5) (Sex determination protein mog-5),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0048589; GO:0010172; GO:0040022; GO:0007281; GO:0006397; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; developmental growth; embryonic body morphogenesis; feminization of hermaphroditic germ-line; germ cell development; mRNA processing; nucleus,PF04408;PF00271;PF07717;PF00575;,0,CHOYP_DHX8.2.3,,,,,,,MOG5_CAEEL,Caenorhabditis elegans,"developmental growth [GO:0048589]; embryonic body morphogenesis [GO:0010172]; feminization of hermaphroditic germ-line [GO:0040022]; germ cell development [GO:0007281]; mRNA splicing, via spliceosome [GO:0000398]" comp143732_c0_seq3,1885,44.3501,0.48842403,4,0,,1.00E-162,O17438,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) (Fragment),Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) (Fragment),GO:0005524; GO:0008026; GO:0008380; GO:0006397; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; RNA splicing; mRNA processing; nucleic acid binding; nucleus,PF04408;PF00271;,0,CHOYP_DHX8.3.3,,,,,,,DHX15_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),"mRNA splicing, via spliceosome [GO:0000398]" comp143733_c1_seq12,430,42.093,0.31691348,0,0,,,,,,,,,3.00E-18,CHOYP_LOC100123553.1.1,,,,,,,,, comp143733_c1_seq9,511,42.0744,0.22176107,8,6,,,,,,,,,3.00E-20,CHOYP_LOC100123553.1.1,,,,,,,,, comp143735_c1_seq1,2116,40.3592,0.33079425,159,1102,,2.00E-24,Q5RB07,WD repeat-containing protein 6,WD repeat-containing protein 6,GO:0007049; GO:0005737,cell cycle; cytoplasm,PF00400;,,,,,,,,,WDR6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell cycle [GO:0007049] comp143735_c2_seq1,763,41.9397,0.18251345,13,134,,7.00E-29,Q5XFW6,WD repeat-containing protein 6,WD repeat-containing protein 6,GO:0008180; GO:0007050; GO:0005737; GO:0008286; GO:0048009; GO:0010507; GO:0008285; GO:0043234,COP9 signalosome; cell cycle arrest; cytoplasm; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; negative regulation of autophagy; negative regulation of cell proliferation; protein complex,PF00400;,2.00E-31,CHOYP_LOC100561297.1.1,,,,,,,WDR6_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286] comp143736_c1_seq2,959,50.7821,0.40515947,17,56,,,,,,,,,2.00E-119,CHOYP_LOC100378364.1.1,,,,,,,,, comp143736_c1_seq3,1060,44.5283,0.36872655,0,0,,3.00E-76,Q960X8,Hepatocyte growth factor-regulated tyrosine kinase substrate,Hepatocyte growth factor-regulated tyrosine kinase substrate,GO:0033565; GO:0007298; GO:0005938; GO:0006897; GO:0016197; GO:0006886; GO:0046872; GO:0007275; GO:0042059; GO:0048471; GO:0045752; GO:0008021; GO:0016082; GO:0008293; GO:0016050,ESCRT-0 complex; border follicle cell migration; cell cortex; endocytosis; endosomal transport; intracellular protein transport; metal ion binding; multicellular organismal development; negative regulation of epidermal growth factor receptor signaling pathway; perinuclear region of cytoplasm; positive regulation of Toll signaling pathway; synaptic vesicle; synaptic vesicle priming; torso signaling pathway; vesicle organization,PF01363;PF12210;PF00790;,,,,,,,,,HRS_DROME,Drosophila melanogaster (Fruit fly),"border follicle cell migration [GO:0007298]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; endosome transport via multivesicular body sorting pathway [GO:0032509]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; membrane protein proteolysis [GO:0033619]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein phosphorylation [GO:0001933]; neuron remodeling [GO:0016322]; neurotransmitter secretion [GO:0007269]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of Toll signaling pathway [GO:0045752]; regulation of cell cycle [GO:0051726]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; regulation of Notch signaling pathway [GO:0008593]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082]; torso signaling pathway [GO:0008293]; vesicle organization [GO:0016050]" comp143736_c1_seq4,1060,44.9057,0.3605297,10,28,,1.00E-102,Q0V8S0,Hepatocyte growth factor-regulated tyrosine kinase substrate,Hepatocyte growth factor-regulated tyrosine kinase substrate,GO:0031901; GO:0016197; GO:0006886; GO:0046872; GO:0032585; GO:0046426,early endosome membrane; endosomal transport; intracellular protein transport; metal ion binding; multivesicular body membrane; negative regulation of JAK-STAT cascade,PF01363;PF12210;PF00790;,,,,,,,,,HGS_BOVIN,Bos taurus (Bovine),membrane invagination [GO:0010324]; negative regulation of JAK-STAT cascade [GO:0046426]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; regulation of MAP kinase activity [GO:0043405] comp143738_c0_seq1,3703,34.9446,0.4269029,1159,11007,,0,Q5BL41,Actin-related protein 2 (Actin-like protein 2),Actin-related protein 2 (Actin-like protein 2),GO:0005524; GO:0034314; GO:0005885; GO:0042995; GO:0005737,ATP binding; Arp2/3 complex-mediated actin nucleation; Arp2/3 protein complex; cell projection; cytoplasm,PF00022;,0,CHOYP_ARP2.1.1,8.00E-79,ruditapes_c15265,,,,,ARP2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),Arp2/3 complex-mediated actin nucleation [GO:0034314] comp143739_c0_seq1,443,38.6005,0,16,94,,8.00E-60,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143740_c0_seq3,2582,48.6057,0.48788601,0,0,,0,P11498,"Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)","Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)",GO:0005524; GO:0003677; GO:0009374; GO:0004075; GO:0006768; GO:0005829; GO:0006094; GO:0006629; GO:0046872; GO:0005743; GO:0005759; GO:0006107; GO:0004736; GO:0006090,ATP binding; DNA binding; biotin binding; biotin carboxylase activity; biotin metabolic process; cytosol; gluconeogenesis; lipid metabolic process; metal ion binding; mitochondrial inner membrane; mitochondrial matrix; oxaloacetate metabolic process; pyruvate carboxylase activity; pyruvate metabolic process,PF02785;PF00289;PF00364;PF02786;PF00682;PF02436;,,,,,,,,,PYC_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; negative regulation of gene expression [GO:0010629]; oxaloacetate metabolic process [GO:0006107]; positive regulation by host of viral process [GO:0044794]; positive regulation by host of viral release from host cell [GO:0044791]; pyruvate metabolic process [GO:0006090]; viral RNA genome packaging [GO:0019074] comp143740_c0_seq4,2558,48.4754,0.48208364,0,0,,0,Q9UUE1,Pyruvate carboxylase (EC 6.4.1.1) (Pyruvic carboxylase) (PCB),Pyruvate carboxylase (EC 6.4.1.1) (Pyruvic carboxylase) (PCB),GO:0005524; GO:0003677; GO:0004075; GO:0005829; GO:0006091; GO:0006094; GO:0046872; GO:0004736,ATP binding; DNA binding; biotin carboxylase activity; cytosol; generation of precursor metabolites and energy; gluconeogenesis; metal ion binding; pyruvate carboxylase activity,PF02785;PF00289;PF00364;PF02786;PF00682;PF02436;,0,CHOYP_LOC100367726.2.2,,,,,,,PYC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),generation of precursor metabolites and energy [GO:0006091]; gluconeogenesis [GO:0006094]; pyruvate metabolic process [GO:0006090] comp143740_c0_seq5,2516,48.7679,0.46420999,0,0,,0,P52873,"Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)","Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)",GO:0005524; GO:0003677; GO:0009374; GO:0004075; GO:0006094; GO:0006629; GO:0046872; GO:0005759; GO:0005739; GO:0006107; GO:0004736; GO:0006090,ATP binding; DNA binding; biotin binding; biotin carboxylase activity; gluconeogenesis; lipid metabolic process; metal ion binding; mitochondrial matrix; mitochondrion; oxaloacetate metabolic process; pyruvate carboxylase activity; pyruvate metabolic process,PF02785;PF00289;PF00364;PF02786;PF00682;PF02436;,0,CHOYP_LOC100367726.1.2,,,,,,,PYC_RAT,Rattus norvegicus (Rat),gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; oxaloacetate metabolic process [GO:0006107]; positive regulation of phospholipid biosynthetic process [GO:0071073]; pyruvate metabolic process [GO:0006090] comp143740_c0_seq6,2540,48.8976,0.47029068,0,0,,,,,,,,,0,CHOYP_LOC100367726.1.2,,,,,,,,, comp143740_c0_seq7,1418,49.0127,0.47651053,0,0,,2.00E-08,O28994,Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (Carbamoyl-phosphate synthetase ammonia chain),Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (Carbamoyl-phosphate synthetase ammonia chain),GO:0044205; GO:0005524; GO:0006526; GO:0004088; GO:0000287; GO:0030145,'de novo' UMP biosynthetic process; ATP binding; arginine biosynthetic process; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; magnesium ion binding; manganese ion binding,PF02786;PF02787;PF02142;,,,,,,,,,CARB_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126),'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526] comp143740_c0_seq8,1394,48.7805,0.46601812,0,0,,3.00E-46,B9FK36,Acetyl-CoA carboxylase 2 (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)],Acetyl-CoA carboxylase 2 (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)],GO:0005524; GO:0003989; GO:0004075; GO:0005829; GO:0006633; GO:2001295; GO:0046872,ATP binding; acetyl-CoA carboxylase activity; biotin carboxylase activity; cytosol; fatty acid biosynthetic process; malonyl-CoA biosynthetic process; metal ion binding,PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;,2.00E-13,CHOYP_MCCA.1.1,,,,,,,ACC2_ORYSJ,Oryza sativa subsp. japonica (Rice),fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295] comp143741_c0_seq2,4938,42.8919,0.8794099,5,0,,,,,,,,,1.00E-61,CHOYP_LOC574069.1.1,,,,,,,,, comp143741_c0_seq3,4693,42.638,0.86589541,18,0,,1.00E-54,Q96PN6,Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase),Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase),GO:0005524; GO:0004016; GO:0045177; GO:0030424; GO:0045178; GO:0005856; GO:0005829; GO:0030425; GO:0030426; GO:0035556; GO:0000287; GO:0030145; GO:0043025; GO:0048471; GO:0005886; GO:0043065; GO:0007283,ATP binding; adenylate cyclase activity; apical part of cell; axon; basal part of cell; cytoskeleton; cytosol; dendrite; growth cone; intracellular signal transduction; magnesium ion binding; manganese ion binding; neuronal cell body; perinuclear region of cytoplasm; plasma membrane; positive regulation of apoptotic process; spermatogenesis,PF00211;,,,,,,,,,ADCYA_HUMAN,Homo sapiens (Human),cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] comp143741_c0_seq5,2027,43.5126,0.90460603,0,0,,9.00E-57,Q96PN6,Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase),Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase),GO:0005524; GO:0004016; GO:0045177; GO:0030424; GO:0045178; GO:0005856; GO:0005829; GO:0030425; GO:0030426; GO:0035556; GO:0000287; GO:0030145; GO:0043025; GO:0048471; GO:0005886; GO:0043065; GO:0007283,ATP binding; adenylate cyclase activity; apical part of cell; axon; basal part of cell; cytoskeleton; cytosol; dendrite; growth cone; intracellular signal transduction; magnesium ion binding; manganese ion binding; neuronal cell body; perinuclear region of cytoplasm; plasma membrane; positive regulation of apoptotic process; spermatogenesis,PF00211;,5.00E-62,CHOYP_LOC574069.1.1,,,,,,,ADCYA_HUMAN,Homo sapiens (Human),cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] comp143742_c0_seq1,2128,40.1786,0.41026784,146,1080,,0,Q2KJC9,Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase),Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase),GO:0004043; GO:0008802; GO:0005829; GO:0019285; GO:0005739; GO:0005634,L-aminoadipate-semialdehyde dehydrogenase activity; betaine-aldehyde dehydrogenase activity; cytosol; glycine betaine biosynthetic process from choline; mitochondrion; nucleus,PF00171;,2.00E-162,CHOYP_LOC100699093.1.1,,,,,,,AL7A1_BOVIN,Bos taurus (Bovine),glycine betaine biosynthetic process from choline [GO:0019285] comp143746_c0_seq1,2348,38.2027,0.54492924,700,131,,0,Q9D5E4,Leucine-rich repeat-containing protein 48,Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48),GO:0005737,cytoplasm,,1.00E-170,CHOYP_LOC100313649.1.1,3.00E-69,ruditapes_c29379,,,,,LRC48_MOUSE,Mus musculus (Mouse), comp143747_c1_seq2,4392,38.8889,0.69698704,230,282,,3.00E-09,C7G0B5,Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)],Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)],GO:0008061; GO:0006030; GO:0005578,chitin binding; chitin metabolic process; proteinaceous extracellular matrix,PF00092;,,,,,,,,,PIF_PINFU,Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata),chitin metabolic process [GO:0006030] comp143749_c0_seq1,5389,42.0672,0.4279736,0,0,,2.00E-123,Q92794,"Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)","Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)",GO:0003677; GO:0006323; GO:0070776; GO:0016605; GO:0035909; GO:0090398; GO:0003682; GO:0035162; GO:0060325; GO:0003007; GO:0043966; GO:0004402; GO:0030099; GO:0043433; GO:0045892; GO:0005730; GO:0000786; GO:0006334; GO:0045893; GO:0035019; GO:0003713; GO:0008134; GO:0006351; GO:0008270,"DNA binding; DNA packaging; MOZ/MORF histone acetyltransferase complex; PML body; aorta morphogenesis; cellular senescence; chromatin binding; embryonic hemopoiesis; face morphogenesis; heart morphogenesis; histone H3 acetylation; histone acetyltransferase activity; myeloid cell differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; nucleolus; nucleosome; nucleosome assembly; positive regulation of transcription, DNA-dependent; somatic stem cell maintenance; transcription coactivator activity; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF01853;PF00628;,2.00E-110,CHOYP_KAT6B.1.2,,,,,,,KAT6A_HUMAN,Homo sapiens (Human),"cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq2,5663,41.109,0.409951,13,66,,2.00E-103,O95251,"Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)","Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)",GO:0006260; GO:0043966; GO:0043983; GO:0043981; GO:0043982; GO:0004402; GO:0000123; GO:0006355; GO:0003700; GO:0006351; GO:0008270,"DNA replication; histone H3 acetylation; histone H4-K12 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity; histone acetyltransferase complex; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01853;PF01530;,2.00E-110,CHOYP_KAT6B.1.2,,,,,,,KAT7_HUMAN,Homo sapiens (Human),"DNA replication [GO:0006260]; histone H3 acetylation [GO:0043966]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq3,1344,41.4435,0.51217267,0,0,,2.00E-35,P58268,Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (Protein requiem),Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (Protein requiem),GO:0006915; GO:0005737; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"apoptotic process; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,,,,,,,,,REQU_CHICK,Gallus gallus (Chicken),"apoptotic process [GO:0006915]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq4,1449,44.8585,0.41197493,326,1025,,8.00E-110,Q04073,DNA-binding protein P3A2,DNA-binding protein P3A2,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10492;PF10491;,8.00E-89,CHOYP_P3A2.2.3,,,,,,,P3A2_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq5,6177,41.007,0.44327855,7,51,,9.00E-123,Q92794,"Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)","Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)",GO:0003677; GO:0006323; GO:0070776; GO:0016605; GO:0035909; GO:0090398; GO:0003682; GO:0035162; GO:0060325; GO:0003007; GO:0043966; GO:0004402; GO:0030099; GO:0043433; GO:0045892; GO:0005730; GO:0000786; GO:0006334; GO:0045893; GO:0035019; GO:0003713; GO:0008134; GO:0006351; GO:0008270,"DNA binding; DNA packaging; MOZ/MORF histone acetyltransferase complex; PML body; aorta morphogenesis; cellular senescence; chromatin binding; embryonic hemopoiesis; face morphogenesis; heart morphogenesis; histone H3 acetylation; histone acetyltransferase activity; myeloid cell differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; nucleolus; nucleosome; nucleosome assembly; positive regulation of transcription, DNA-dependent; somatic stem cell maintenance; transcription coactivator activity; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF01853;PF00628;,4.00E-107,CHOYP_KAT6B.2.2,,,,,,,KAT6A_HUMAN,Homo sapiens (Human),"cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq6,7760,38.9948,0.43061211,1955,4703,,9.00E-122,Q5TKR9,"Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein)","Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein)",GO:0003677; GO:0070776; GO:0016605; GO:0090398; GO:0043966; GO:0004402; GO:0030099; GO:0045892; GO:0005730; GO:0000786; GO:0006334; GO:0045893; GO:0008134; GO:0006351; GO:0008270,"DNA binding; MOZ/MORF histone acetyltransferase complex; PML body; cellular senescence; histone H3 acetylation; histone acetyltransferase activity; myeloid cell differentiation; negative regulation of transcription, DNA-dependent; nucleolus; nucleosome; nucleosome assembly; positive regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF01853;PF00628;,,,5.00E-16,ruditapes_c8528,,,,,KAT6A_RAT,Rattus norvegicus (Rat),"cellular senescence [GO:0090398]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq7,4817,41.5611,0.37089811,13,10,,7.00E-125,Q92794,"Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)","Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)",GO:0003677; GO:0006323; GO:0070776; GO:0016605; GO:0035909; GO:0090398; GO:0003682; GO:0035162; GO:0060325; GO:0003007; GO:0043966; GO:0004402; GO:0030099; GO:0043433; GO:0045892; GO:0005730; GO:0000786; GO:0006334; GO:0045893; GO:0035019; GO:0003713; GO:0008134; GO:0006351; GO:0008270,"DNA binding; DNA packaging; MOZ/MORF histone acetyltransferase complex; PML body; aorta morphogenesis; cellular senescence; chromatin binding; embryonic hemopoiesis; face morphogenesis; heart morphogenesis; histone H3 acetylation; histone acetyltransferase activity; myeloid cell differentiation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; nucleolus; nucleosome; nucleosome assembly; positive regulation of transcription, DNA-dependent; somatic stem cell maintenance; transcription coactivator activity; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF01853;PF00628;,2.00E-110,CHOYP_KAT6B.1.2,,,,,,,KAT6A_HUMAN,Homo sapiens (Human),"cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq8,4801,42.3037,0.40512284,0,8,,8.00E-125,Q5TKR9,"Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein)","Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein)",GO:0003677; GO:0070776; GO:0016605; GO:0090398; GO:0043966; GO:0004402; GO:0030099; GO:0045892; GO:0005730; GO:0000786; GO:0006334; GO:0045893; GO:0008134; GO:0006351; GO:0008270,"DNA binding; MOZ/MORF histone acetyltransferase complex; PML body; cellular senescence; histone H3 acetylation; histone acetyltransferase activity; myeloid cell differentiation; negative regulation of transcription, DNA-dependent; nucleolus; nucleosome; nucleosome assembly; positive regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF01853;PF00628;,2.00E-110,CHOYP_KAT6B.1.2,,,,,,,KAT6A_RAT,Rattus norvegicus (Rat),"cellular senescence [GO:0090398]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; transcription, DNA-templated [GO:0006351]" comp143749_c0_seq9,2132,38.6961,0.54970944,0,0,,5.00E-35,P58268,Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (Protein requiem),Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (Protein requiem),GO:0006915; GO:0005737; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"apoptotic process; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF14051;,,,,,,,,,REQU_CHICK,Gallus gallus (Chicken),"apoptotic process [GO:0006915]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143750_c0_seq1,1912,44.4561,0.89409956,3,22,,2.00E-143,Q9Y345,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015375; GO:0016021; GO:0005328; GO:0005886; GO:0007268,glycine:sodium symporter activity; integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane; synaptic transmission,PF00209;,4.00E-31,CHOYP_SC6A7.1.1,,,,,,,SC6A5_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp143750_c0_seq2,973,43.8849,0.83621803,2,0,,3.00E-17,Q9GZN6,Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16),Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16),GO:0016021; GO:0005622; GO:0005326; GO:0005328,integral to membrane; intracellular; neurotransmitter transporter activity; neurotransmitter:sodium symporter activity,PF00209;,2.00E-11,CHOYP_LOC100368611.1.1,,,,,,,S6A16_HUMAN,Homo sapiens (Human),neurotransmitter transport [GO:0006836] comp143750_c0_seq3,2100,44.0952,0.87462659,8,6,,,,,,,,,1.00E-26,CHOYP_SC6A9.6.6,,,,,,,,, comp143750_c0_seq4,1524,44.357,0.88178129,0,7,,1.00E-107,Q761V0,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0016021; GO:0005328,integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,3.00E-31,CHOYP_SC6A7.1.1,,,,,,,SC6A5_MOUSE,Mus musculus (Mouse),"glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]" comp143750_c1_seq3,2888,30.6787,0.78405749,9,18,,5.00E-13,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143750_c1_seq6,2845,30.6503,0.73642196,16,8,,3.00E-16,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143751_c1_seq2,2092,33.1262,0.80471759,0,6,,1.00E-23,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp143751_c1_seq3,2424,31.3119,0.79347688,37,157,,9.00E-23,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp143751_c1_seq5,2957,31.6199,0.77152515,24,700,,3.00E-23,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp143752_c0_seq2,1752,30.9932,0.67618151,60,90,,2.00E-11,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp143754_c0_seq1,2814,40.334,0.4911914,109,778,,9.00E-86,P33731,Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein),Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein),GO:0008312; GO:0006614; GO:0005829; GO:0005783; GO:0005730; GO:0005886; GO:0042493; GO:0005047; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosol; endoplasmic reticulum; nucleolus; plasma membrane; response to drug; signal recognition particle binding; signal recognition particle, endoplasmic reticulum targeting",PF08492;PF17004;PF13181;,1.00E-122,CHOYP_SRP72.1.1,,,,,,,SRP72_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp143754_c0_seq2,2814,40.5828,0.51143211,40,263,,9.00E-86,P33731,Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein),Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein),GO:0008312; GO:0006614; GO:0005829; GO:0005783; GO:0005730; GO:0005886; GO:0042493; GO:0005047; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosol; endoplasmic reticulum; nucleolus; plasma membrane; response to drug; signal recognition particle binding; signal recognition particle, endoplasmic reticulum targeting",PF08492;PF17004;PF13181;,1.00E-122,CHOYP_SRP72.1.1,,,,,,,SRP72_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp143755_c0_seq1,1004,36.753,0.53874614,52,274,,1.00E-63,Q2YDE7,Protein archease (Protein ZBTB8OS),Protein archease (Protein ZBTB8OS),,,PF01951;,3.00E-92,CHOYP_SMP_054450.1.1,,,,,,,ARCH_BOVIN,Bos taurus (Bovine),"tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" comp143756_c0_seq2,2407,33.818,0.59310355,2,68,,3.00E-32,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp143756_c0_seq3,2330,33.5622,0.59065793,3,6,,,,,,,,,8.00E-22,CHOYP_LOC100892567.3.8,6.00E-15,ruditapes_c16815,,,,,,, comp143757_c0_seq1,3087,42.598,0.3748273,82,0,,1.00E-173,Q5VTH9,WD repeat-containing protein 78,WD repeat-containing protein 78,,,PF00400;,,,,,,,,,WDR78_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244] comp143757_c0_seq2,3075,42.6341,0.37567352,12,47,,3.00E-171,Q4V8G4,WD repeat-containing protein 78,WD repeat-containing protein 78,,,PF00400;,0,CHOYP_LOC574740.1.1,,,,,,,WDR78_RAT,Rattus norvegicus (Rat),hematopoietic progenitor cell differentiation [GO:0002244] comp143757_c0_seq4,659,45.3718,0.51261083,0,0,,1.00E-07,Q54WA3,Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),GO:0005777; GO:0005053; GO:0007031; GO:0015031,peroxisome; peroxisome matrix targeting signal-2 binding; peroxisome organization; protein transport,PF00400;,,,,,,,,,PEX7_DICDI,Dictyostelium discoideum (Slime mold),peroxisome organization [GO:0007031]; protein transport [GO:0015031] comp143760_c0_seq1,3084,38.4241,0.59275208,15,62,,5.00E-155,O77503,Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) (Fragment),Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) (Fragment),GO:0016442; GO:0000340; GO:0000932; GO:0070551; GO:0005845; GO:0035279; GO:0046872; GO:0035068; GO:0035278; GO:0045947; GO:0005634; GO:0005844; GO:1900153; GO:0060213; GO:0031054; GO:0006355; GO:0035197; GO:0006351,"RISC complex; RNA 7-methylguanosine cap binding; cytoplasmic mRNA processing body; endoribonuclease activity, cleaving siRNA-paired mRNA; mRNA cap binding complex; mRNA cleavage involved in gene silencing by miRNA; metal ion binding; micro-ribonucleoprotein complex; negative regulation of translation involved in gene silencing by miRNA; negative regulation of translational initiation; nucleus; polysome; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; pre-miRNA processing; regulation of transcription, DNA-dependent; siRNA binding; transcription, DNA-dependent",PF08699;PF16488;PF16487;PF16486;PF02170;PF02171;,,,,,,,,,AGO2_RABIT,Oryctolagus cuniculus (Rabbit),"gene silencing by RNA [GO:0031047]; miRNA mediated inhibition of translation [GO:0035278]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143760_c0_seq2,1951,47.5141,0.47248095,16,69,,0,Q9QZ81,Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer),Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer),GO:0016442; GO:0000340; GO:0030154; GO:0000932; GO:0070551; GO:0005845; GO:0035279; GO:0046872; GO:0035068; GO:0035278; GO:0045947; GO:0005634; GO:0005844; GO:1900153; GO:0060213; GO:0031054; GO:0006355; GO:0035197; GO:0006351,"RISC complex; RNA 7-methylguanosine cap binding; cell differentiation; cytoplasmic mRNA processing body; endoribonuclease activity, cleaving siRNA-paired mRNA; mRNA cap binding complex; mRNA cleavage involved in gene silencing by miRNA; metal ion binding; micro-ribonucleoprotein complex; negative regulation of translation involved in gene silencing by miRNA; negative regulation of translational initiation; nucleus; polysome; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; pre-miRNA processing; regulation of transcription, DNA-dependent; siRNA binding; transcription, DNA-dependent",PF08699;PF16488;PF16487;PF16486;PF02170;PF02171;,0,CHOYP_LOC100908241.1.1,,,,,,,AGO2_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; miRNA mediated inhibition of translation [GO:0035278]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143760_c0_seq3,2433,39.9918,0.54719375,0,0,,5.00E-48,Q5NBN9,Protein argonaute 15 (OsAGO15),Protein argonaute 15 (OsAGO15),GO:0031047; GO:0003676,gene silencing by RNA; nucleic acid binding,PF08699;PF16488;PF16486;PF02170;PF02171;,,,,,,,,,AGO15_ORYSJ,Oryza sativa subsp. japonica (Rice),gene silencing by RNA [GO:0031047] comp143760_c0_seq4,1210,46.3636,0.56948437,0,3,,3.00E-87,Q9C793,Protein argonaute 7 (Protein ZIPPY),Protein argonaute 7 (Protein ZIPPY),GO:0003723; GO:0005737; GO:0006952; GO:0035195; GO:0010599; GO:0010267; GO:0040034; GO:0006355; GO:0006417; GO:0030529; GO:0006351; GO:0010050,"RNA binding; cytoplasm; defense response; gene silencing by miRNA; production of lsiRNA involved in RNA interference; production of ta-siRNAs involved in RNA interference; regulation of development, heterochronic; regulation of transcription, DNA-dependent; regulation of translation; ribonucleoprotein complex; transcription, DNA-dependent; vegetative phase change",PF08699;PF16488;PF16486;PF02170;PF02171;,0,CHOYP_ISCW_ISCW013378.2.3,,,,,,,AGO7_ARATH,Arabidopsis thaliana (Mouse-ear cress),"defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; production of lsiRNA involved in RNA interference [GO:0010599]; production of ta-siRNAs involved in RNA interference [GO:0010267]; regulation of development, heterochronic [GO:0040034]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; vegetative phase change [GO:0010050]; viral gene silencing in virus induced gene silencing [GO:0060145]" comp143760_c0_seq5,2769,39.0755,0.54242641,0,0,,9.00E-66,Q7XTS4,Protein argonaute 2 (OsAGO2),Protein argonaute 2 (OsAGO2),GO:0031047; GO:0003676,gene silencing by RNA; nucleic acid binding,PF08699;PF16488;PF16486;PF02170;PF02171;,0,CHOYP_AGO1.1.1,,,,,,,AGO2_ORYSJ,Oryza sativa subsp. japonica (Rice),gene silencing by RNA [GO:0031047] comp143760_c0_seq8,1446,46.6805,0.45768631,3,29,,0,Q9QZ81,Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer),Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer),GO:0016442; GO:0000340; GO:0030154; GO:0000932; GO:0070551; GO:0005845; GO:0035279; GO:0046872; GO:0035068; GO:0035278; GO:0045947; GO:0005634; GO:0005844; GO:1900153; GO:0060213; GO:0031054; GO:0006355; GO:0035197; GO:0006351,"RISC complex; RNA 7-methylguanosine cap binding; cell differentiation; cytoplasmic mRNA processing body; endoribonuclease activity, cleaving siRNA-paired mRNA; mRNA cap binding complex; mRNA cleavage involved in gene silencing by miRNA; metal ion binding; micro-ribonucleoprotein complex; negative regulation of translation involved in gene silencing by miRNA; negative regulation of translational initiation; nucleus; polysome; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; pre-miRNA processing; regulation of transcription, DNA-dependent; siRNA binding; transcription, DNA-dependent",PF08699;PF16488;PF16487;PF16486;PF02170;PF02171;,0,CHOYP_ISCW_ISCW013378.2.3,,,,,,,AGO2_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; miRNA mediated inhibition of translation [GO:0035278]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143761_c0_seq2,2750,44.5818,0.36947207,18,0,,2.00E-43,O42945,Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43 (EC 3.6.4.13),Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43 (EC 3.6.4.13),GO:0030686; GO:0005524; GO:0004004; GO:0005684; GO:0003676; GO:0006364; GO:0000390,90S preribosome; ATP binding; ATP-dependent RNA helicase activity; U2-type spliceosomal complex; nucleic acid binding; rRNA processing; spliceosomal complex disassembly,PF00270;PF04408;PF00271;PF07717;,1.00E-97,CHOYP_YTDC2.1.1,,,,,,,DHX15_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; spliceosomal complex disassembly [GO:0000390]" comp143761_c0_seq3,1642,47.0158,0.34593715,333,92,,1.00E-77,Q5R746,YTH domain-containing protein 2,YTH domain-containing protein 2,GO:0004386,helicase activity,PF04408;PF07717;PF04146;,,,,,,,,,YTDC2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp143761_c0_seq4,544,46.5074,0.34511262,43,0,,9.00E-32,Q0DA50,Zinc finger CCCH domain-containing protein 45 (OsC3H45),Zinc finger CCCH domain-containing protein 45 (OsC3H45),GO:0003677; GO:0046872,DNA binding; metal ion binding,PF04146;,,,,,,,,,C3H45_ORYSJ,Oryza sativa subsp. japonica (Rice), comp143761_c0_seq5,832,44.9519,0.33373446,0,0,,9.00E-06,Q8BY02,NF-kappa-B-repressing factor (NFkB-repressing factor) (Transcription factor NRF),NF-kappa-B-repressing factor (NFkB-repressing factor) (Transcription factor NRF),GO:0003677; GO:0045892; GO:0005730; GO:0006351,"DNA binding; negative regulation of transcription, DNA-dependent; nucleolus; transcription, DNA-dependent",PF01585;PF01424;,,,,,,,,,NKRF_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp143761_c0_seq6,2258,44.5084,0.35166417,14,0,,0,B2RR83,Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13),Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;PF01424;PF04146;,8.00E-98,CHOYP_YTDC2.1.1,,,,,,,YTDC2_MOUSE,Mus musculus (Mouse),positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; RNA processing [GO:0006396] comp143761_c0_seq8,664,45.4819,0.35000079,0,0,,2.00E-94,Q9H6S0,Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13),Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;PF01424;PF04146;,,,,,,,,,YTDC2_HUMAN,Homo sapiens (Human),positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; RNA processing [GO:0006396] comp143765_c2_seq1,3485,42.4103,0.46018522,413,1769,,0,Q8C0S1,DIS3-like exonuclease 1 (EC 3.1.13.-),DIS3-like exonuclease 1 (EC 3.1.13.-),GO:0000175; GO:0003723; GO:0000177; GO:0016075,3'-5'-exoribonuclease activity; RNA binding; cytoplasmic exosome (RNase complex); rRNA catabolic process,,0,CHOYP_DI3L1.1.1,,,,,,,DI3L1_MOUSE,Mus musculus (Mouse),mRNA catabolic process [GO:0006402]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364] comp143766_c0_seq1,3024,46.627,0.44430164,935,1010,,3.00E-55,Q9JII5,DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1),DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1),GO:0035613; GO:0030154; GO:0008283; GO:0005737; GO:0001893; GO:0000166; GO:0005634; GO:0007283,RNA stem-loop binding; cell differentiation; cell proliferation; cytoplasm; maternal placenta development; nucleotide binding; nucleus; spermatogenesis,PF00076;,1.00E-40,CHOYP_AAEL_AAEL008257.3.3,,,,,,,DAZP1_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]" comp143766_c0_seq2,2991,46.6065,0.43112397,554,888,,3.00E-55,Q9JII5,DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1),DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1),GO:0035613; GO:0030154; GO:0008283; GO:0005737; GO:0001893; GO:0000166; GO:0005634; GO:0007283,RNA stem-loop binding; cell differentiation; cell proliferation; cytoplasm; maternal placenta development; nucleotide binding; nucleus; spermatogenesis,PF00076;,1.00E-40,CHOYP_AAEL_AAEL008257.3.3,9.00E-27,ruditapes_c182,,,,,DAZP1_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]" comp143767_c0_seq5,2281,41.9553,0.42881623,0,0,,2.00E-09,Q68CJ6,Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),GO:0005525; GO:0006184; GO:0003924; GO:0005634,GTP binding; GTP catabolic process; GTPase activity; nucleus,PF00350;,,,,,,,,,SLIP_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp143768_c1_seq2,1557,40.5267,0.64778447,86,634,,9.00E-141,Q9Y4P3,Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein),Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein),,,PF00400;,6.00E-66,CHOYP_TBL2.1.1,,,,,,,TBL2_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968] comp143769_c0_seq1,2427,48.0016,0.30919316,196,52,,1.00E-173,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,1.00E-139,CHOYP_HERC2.1.1,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp143769_c1_seq1,2452,51.5905,0.39436702,232,143,,3.00E-93,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,0,CHOYP_HERC2.1.1,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp143769_c1_seq2,1638,45.177,0.33641228,113,184,,6.00E-45,Q3U487,E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),GO:0005634; GO:0048471; GO:0043161; GO:0042787; GO:0004842,nucleus; perinuclear region of cytoplasm; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF03256;PF00632;,,,,,,,,,HECD3_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp143769_c1_seq4,3859,49.3392,0.36356184,389,116,,0,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp143770_c0_seq1,2500,34.24,0.44177774,0,0,,1.00E-112,Q6P799,"Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)","Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)",GO:0005524; GO:0005737; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,2.00E-119,CHOYP_LOC656867.1.1,,,,,,,SYSC_RAT,Rattus norvegicus (Rat),selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp143770_c0_seq2,4151,33.8954,0.5067473,18,38,,2.00E-82,P26636,"Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) (Fragment)","Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) (Fragment)",GO:0005524; GO:0005737; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF00587;,,,,,,,,,SYSC_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp143770_c0_seq3,3303,36.3003,0.50723258,0,0,,0,Q6P799,"Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)","Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)",GO:0005524; GO:0005737; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,0,CHOYP_LOC656867.1.1,,,,,,,SYSC_RAT,Rattus norvegicus (Rat),selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp143770_c0_seq4,4958,35.3368,0.53676272,231,820,,0,Q18678,"Probable serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)","Probable serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)",GO:0005524; GO:0005737; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,,,2.00E-11,ruditapes_c25051,,,,,SYSC_CAEEL,Caenorhabditis elegans,negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]; translation [GO:0006412] comp143771_c1_seq1,3140,49.8089,0.36863581,651,845,,5.00E-83,Q96L91,E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein),E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein),GO:0005524; GO:0003677; GO:0035267; GO:0003682; GO:0004386; GO:0043968; GO:0043967; GO:0016607,ATP binding; DNA binding; NuA4 histone acetyltransferase complex; chromatin binding; helicase activity; histone H2A acetylation; histone H4 acetylation; nuclear speck,PF15790;PF00271;PF07529;PF00176;,3.00E-99,CHOYP_LOC100115939.1.1,,,,,,,EP400_HUMAN,Homo sapiens (Human),histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967] comp143772_c2_seq1,344,36.6279,0.65625555,0,0,,5.00E-10,Q9DBT3,Coiled-coil domain-containing protein 97,Coiled-coil domain-containing protein 97,,,PF09747;,,,,,,,,,CCD97_MOUSE,Mus musculus (Mouse), comp143773_c0_seq1,3666,39.9891,0.43032854,11,104,,8.00E-129,A9JTG5,RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 6.3.2.-) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1),RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 6.3.2.-) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1),GO:0003677; GO:0071797; GO:0048701; GO:0071600; GO:0043123; GO:0097039; GO:0006351; GO:0043130; GO:0004842; GO:0008270,"DNA binding; LUBAC complex; embryonic cranial skeleton morphogenesis; otic vesicle morphogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein linear polyubiquitination; transcription, DNA-dependent; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding",PF01485;PF16764;PF00641;,2.00E-89,CHOYP_HOIL1.2.3,,,,,,,HOIL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic cranial skeleton morphogenesis [GO:0048701]; otic vesicle morphogenesis [GO:0071600]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039] comp143773_c0_seq2,3687,40.0054,0.42747544,4,46,,9.00E-129,A9JTG5,RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 6.3.2.-) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1),RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 6.3.2.-) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1),GO:0003677; GO:0071797; GO:0048701; GO:0071600; GO:0043123; GO:0097039; GO:0006351; GO:0043130; GO:0004842; GO:0008270,"DNA binding; LUBAC complex; embryonic cranial skeleton morphogenesis; otic vesicle morphogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein linear polyubiquitination; transcription, DNA-dependent; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding",PF01485;PF16764;PF00641;,2.00E-89,CHOYP_HOIL1.2.3,,,,,,,HOIL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic cranial skeleton morphogenesis [GO:0048701]; otic vesicle morphogenesis [GO:0071600]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039] comp143773_c0_seq3,1818,41.4741,0.52620863,36,139,,5.00E-09,E1BDF2,Sharpin (Shank-associated RH domain-interacting protein),Sharpin (Shank-associated RH domain-interacting protein),GO:0071797; GO:0030262; GO:0005829; GO:0031424; GO:0007005; GO:0050728; GO:0031593; GO:0043123; GO:0097039; GO:2000348; GO:0010803; GO:0008270,LUBAC complex; apoptotic nuclear changes; cytosol; keratinization; mitochondrion organization; negative regulation of inflammatory response; polyubiquitin binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein linear polyubiquitination; regulation of CD40 signaling pathway; regulation of tumor necrosis factor-mediated signaling pathway; zinc ion binding,PF16764;,1.00E-12,CHOYP_HOIL1.3.3,,,,,,,SHRPN_BOVIN,Bos taurus (Bovine),apoptotic nuclear changes [GO:0030262]; keratinization [GO:0031424]; mitochondrion organization [GO:0007005]; negative regulation of inflammatory response [GO:0050728]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039]; regulation of CD40 signaling pathway [GO:2000348]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803] comp143775_c0_seq1,1920,38.3854,0.4428902,207,673,,3.00E-114,Q9Y606,"tRNA pseudouridine synthase A, mitochondrial (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)","tRNA pseudouridine synthase A, mitochondrial (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)",GO:0003677; GO:0003723; GO:0030374; GO:0005739; GO:0005730; GO:0005634; GO:0045944; GO:0009982; GO:0004730; GO:0008033; GO:0031119; GO:0005667,DNA binding; RNA binding; ligand-dependent nuclear receptor transcription coactivator activity; mitochondrion; nucleolus; nucleus; positive regulation of transcription from RNA polymerase II promoter; pseudouridine synthase activity; pseudouridylate synthase activity; tRNA processing; tRNA pseudouridine synthesis; transcription factor complex,PF01416;,4.00E-31,CHOYP_LOC100079978.1.1,,,,,,,TRUA_HUMAN,Homo sapiens (Human),mitochondrial tRNA pseudouridine synthesis [GO:0070902] comp143776_c0_seq3,966,33.9545,0.32401375,369,2932,,6.00E-45,P62313,U6 snRNA-associated Sm-like protein LSm6,U6 snRNA-associated Sm-like protein LSm6,GO:0003723; GO:0008380; GO:0005737; GO:0006397; GO:0006364; GO:0005681; GO:0008033,RNA binding; RNA splicing; cytoplasm; mRNA processing; rRNA processing; spliceosomal complex; tRNA processing,PF01423;,,,5.00E-37,ruditapes_c29800,,,,,LSM6_MOUSE,Mus musculus (Mouse),"maturation of SSU-rRNA [GO:0030490]; mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]" comp143777_c0_seq1,2291,39.1532,0.43527115,16,141,,1.00E-82,Q9D799,"Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)","Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)",GO:0004479; GO:0005739; GO:0006413,methionyl-tRNA formyltransferase activity; mitochondrion; translational initiation,PF02911;PF00551;,5.00E-18,CHOYP_MTFMT.1.1,,,,,,,FMT_MOUSE,Mus musculus (Mouse), comp143777_c0_seq2,2231,39.8028,0.45482574,33,111,,8.00E-83,Q9D799,"Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)","Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)",GO:0004479; GO:0005739; GO:0006413,methionyl-tRNA formyltransferase activity; mitochondrion; translational initiation,PF02911;PF00551;,5.00E-18,CHOYP_MTFMT.1.1,,,,,,,FMT_MOUSE,Mus musculus (Mouse), comp143778_c2_seq1,3175,40.063,0.46877061,176,1189,,0,Q4R367,E3 UFM1-protein ligase 1 (EC 6.3.2.-),E3 UFM1-protein ligase 1 (EC 6.3.2.-),GO:0071568; GO:0005783; GO:0032088; GO:0031397; GO:0071569,UFM1 conjugating enzyme activity; endoplasmic reticulum; negative regulation of NF-kappaB transcription factor activity; negative regulation of protein ubiquitination; protein ufmylation,PF09743;,8.00E-87,CHOYP_UFL1.1.1,,,,,,,UFL1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein ubiquitination [GO:0031397]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146] comp143778_c2_seq2,2549,41.5849,0.42164524,12,213,,3.00E-142,B3RYG4,E3 UFM1-protein ligase 1 homolog (EC 6.3.2.-),E3 UFM1-protein ligase 1 homolog (EC 6.3.2.-),GO:0016874,ligase activity,PF09743;,6.00E-87,CHOYP_UFL1.1.1,,,,,,,UFL1_TRIAD,Trichoplax adhaerens (Trichoplax reptans), comp143779_c0_seq2,2873,44.2395,0.44275376,147,120,,7.00E-79,A2AKX3,Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein homolog) (SEN1 homolog),Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein homolog) (SEN1 homolog),GO:0005524; GO:0007623; GO:0005737; GO:0006302; GO:0004386; GO:0005730; GO:0005654; GO:0006369,ATP binding; circadian rhythm; cytoplasm; double-strand break repair; helicase activity; nucleolus; nucleoplasm; termination of RNA polymerase II transcription,,,,,,,,,,SETX_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA-templated transcription, termination [GO:0006353]; double-strand break repair [GO:0006302]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; positive regulation of DNA-templated transcription, termination [GO:0060566]; positive regulation of neuron projection development [GO:0010976]; positive regulation of RNA splicing [GO:0033120]; positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000806]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein kinase B signaling [GO:0043491]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369]" comp143779_c0_seq3,1519,43.5813,0.36370011,16,0,,1.00E-17,P38859,DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],GO:0051539; GO:0043139; GO:0017108; GO:0005524; GO:0004003; GO:0003677; GO:0033567; GO:0000733; GO:0005829; GO:0006273; GO:0000706; GO:0046872; GO:0000784; GO:0001302; GO:0000014; GO:0043142; GO:0035861; GO:0000723,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; 5'-flap endonuclease activity; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA replication, Okazaki fragment processing; DNA strand renaturation; cytosol; lagging strand elongation; meiotic DNA double-strand break processing; metal ion binding; nuclear chromosome, telomeric region; replicative cell aging; single-stranded DNA endodeoxyribonuclease activity; single-stranded DNA-dependent ATPase activity; site of double-strand break; telomere maintenance",PF08696;,,,,,,,,,DNA2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA double-strand break processing [GO:0000729]; DNA repair [GO:0006281]; DNA strand renaturation [GO:0000733]; lagging strand elongation [GO:0006273]; meiotic DNA double-strand break processing [GO:0000706]; replicative cell aging [GO:0001302]; small molecule metabolic process [GO:0044281]; telomere maintenance [GO:0000723] comp143779_c0_seq4,620,42.9032,0.61062106,0,0,,4.00E-18,P51530,DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)],GO:0051539; GO:0043139; GO:0017108; GO:0005524; GO:0003677; GO:0000729; GO:0000076; GO:0043137; GO:0006284; GO:0046872; GO:0043504; GO:0006264; GO:0042645; GO:0000278; GO:0005654; GO:0045740; GO:0043142; GO:0016890; GO:0000722; GO:0032201,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; 5'-flap endonuclease activity; ATP binding; DNA binding; DNA double-strand break processing; DNA replication checkpoint; DNA replication, removal of RNA primer; base-excision repair; metal ion binding; mitochondrial DNA repair; mitochondrial DNA replication; mitochondrial nucleoid; mitotic cell cycle; nucleoplasm; positive regulation of DNA replication; single-stranded DNA-dependent ATPase activity; site-specific endodeoxyribonuclease activity, specific for altered base; telomere maintenance via recombination; telomere maintenance via semi-conservative replication",PF08696;,,,,,,,,,DNA2_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; DNA replication checkpoint [GO:0000076]; DNA synthesis involved in DNA repair [GO:0000731]; mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA replication [GO:0045740]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]" comp143783_c0_seq1,5395,42.1131,0.48684315,558,205,,0,Q8NI27,THO complex subunit 2 (Tho2) (hTREX120),THO complex subunit 2 (Tho2) (hTREX120),GO:0003723; GO:0008380; GO:0000445; GO:0046784; GO:0006397,RNA binding; RNA splicing; THO complex part of transcription export complex; intronless viral mRNA export from host nucleus; mRNA processing,PF11262;PF11732;PF16134;,0,CHOYP_THOC2.2.2,5.00E-33,ruditapes_c11839,,,,,THOC2_HUMAN,Homo sapiens (Human),generation of neurons [GO:0048699]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]; viral mRNA export from host cell nucleus [GO:0046784] comp143783_c0_seq2,1213,38.7469,0.71358032,7,12,,,,,,,,,,,6.00E-12,ruditapes_c30753,,,,,,, comp143783_c0_seq3,3941,40.3451,0.47963194,226,59,,0,B1AZI6,THO complex subunit 2 (Tho2),THO complex subunit 2 (Tho2),GO:0003723; GO:0008380; GO:0006397; GO:0051028; GO:0005634,RNA binding; RNA splicing; mRNA processing; mRNA transport; nucleus,PF11262;PF11732;PF16134;,0,CHOYP_THOC2.2.2,,,,,,,THOC2_MOUSE,Mus musculus (Mouse),blastocyst development [GO:0001824]; cell morphogenesis [GO:0000902]; generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; RNA splicing [GO:0008380]; stem cell division [GO:0017145]; viral mRNA export from host cell nucleus [GO:0046784] comp143784_c0_seq1,3738,45.9604,0.62113022,0,3,,1.00E-68,Q80U72,Protein scribble homolog (Scribble) (Protein LAP4),Protein scribble homolog (Scribble) (Protein LAP4),GO:0032863; GO:0060561; GO:0008105; GO:0016323; GO:0016477; GO:0008283; GO:0005913; GO:0016337; GO:0005737; GO:0035089; GO:0060603; GO:0035748; GO:0045930; GO:0001843; GO:0050918; GO:0043065; GO:0048488; GO:0016080; GO:0042060,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; asymmetric protein localization; basolateral plasma membrane; cell migration; cell proliferation; cell-cell adherens junction; cell-cell adhesion; cytoplasm; establishment of apical/basal cell polarity; mammary gland duct morphogenesis; myelin sheath abaxonal region; negative regulation of mitotic cell cycle; neural tube closure; positive chemotaxis; positive regulation of apoptotic process; synaptic vesicle endocytosis; synaptic vesicle targeting; wound healing,PF13855;PF00595;,4.00E-54,CHOYP_LOC100877438.2.2,,,,,,,SCRIB_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; asymmetric protein localization [GO:0008105]; auditory receptor cell morphogenesis [GO:0002093]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; mammary gland duct morphogenesis [GO:0060603]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; protein localization to adherens junction [GO:0071896]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp143784_c0_seq10,3855,46.511,0.64983901,0,0,,4.00E-07,Q80TH2,Protein LAP2 (Densin-180-like protein) (Erbb2-interacting protein) (Erbin),Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2),GO:0016323; GO:0030056; GO:0031965; GO:0006605,basolateral plasma membrane; hemidesmosome; nuclear membrane; protein targeting,PF13855;PF00595;,,,,,,,,,LAP2_MOUSE,Mus musculus (Mouse),cellular response to tumor necrosis factor [GO:0071356]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165] comp143784_c0_seq11,3681,46.1016,0.6164407,0,0,,8.00E-69,Q80U72,Protein scribble homolog (Scribble) (Protein LAP4),Protein scribble homolog (Scribble) (Protein LAP4),GO:0032863; GO:0060561; GO:0008105; GO:0016323; GO:0016477; GO:0008283; GO:0005913; GO:0016337; GO:0005737; GO:0035089; GO:0060603; GO:0035748; GO:0045930; GO:0001843; GO:0050918; GO:0043065; GO:0048488; GO:0016080; GO:0042060,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; asymmetric protein localization; basolateral plasma membrane; cell migration; cell proliferation; cell-cell adherens junction; cell-cell adhesion; cytoplasm; establishment of apical/basal cell polarity; mammary gland duct morphogenesis; myelin sheath abaxonal region; negative regulation of mitotic cell cycle; neural tube closure; positive chemotaxis; positive regulation of apoptotic process; synaptic vesicle endocytosis; synaptic vesicle targeting; wound healing,PF13855;PF00595;,3.00E-54,CHOYP_ISCW_ISCW019590.1.1,,,,,,,SCRIB_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; asymmetric protein localization [GO:0008105]; auditory receptor cell morphogenesis [GO:0002093]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; mammary gland duct morphogenesis [GO:0060603]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; protein localization to adherens junction [GO:0071896]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp143784_c0_seq12,3834,46.5832,0.64644403,0,0,,4.00E-73,Q4H4B6,Protein scribble homolog (Scribble1),Protein scribble homolog (Scribble1),GO:0032863; GO:0060561; GO:0008283; GO:0005913; GO:0016337; GO:0060027; GO:0005737; GO:0035089; GO:0000132; GO:0045930; GO:0001764; GO:0005886; GO:0050918; GO:0043065; GO:0014021,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; cell proliferation; cell-cell adherens junction; cell-cell adhesion; convergent extension involved in gastrulation; cytoplasm; establishment of apical/basal cell polarity; establishment of mitotic spindle orientation; negative regulation of mitotic cell cycle; neuron migration; plasma membrane; positive chemotaxis; positive regulation of apoptotic process; secondary neural tube formation,PF13855;PF00595;,4.00E-54,CHOYP_LOC100877438.2.2,,,,,,,SCRIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944] comp143784_c0_seq13,3867,46.496,0.64835513,0,0,,3.00E-10,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,,,,,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp143784_c0_seq14,3693,46.0872,0.62007643,0,0,,3.00E-73,Q4H4B6,Protein scribble homolog (Scribble1),Protein scribble homolog (Scribble1),GO:0032863; GO:0060561; GO:0008283; GO:0005913; GO:0016337; GO:0060027; GO:0005737; GO:0035089; GO:0000132; GO:0045930; GO:0001764; GO:0005886; GO:0050918; GO:0043065; GO:0014021,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; cell proliferation; cell-cell adherens junction; cell-cell adhesion; convergent extension involved in gastrulation; cytoplasm; establishment of apical/basal cell polarity; establishment of mitotic spindle orientation; negative regulation of mitotic cell cycle; neuron migration; plasma membrane; positive chemotaxis; positive regulation of apoptotic process; secondary neural tube formation,PF13855;PF00595;,3.00E-54,CHOYP_LOC100877438.2.2,,,,,,,SCRIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944] comp143784_c0_seq15,3759,45.8899,0.62466406,0,0,,3.00E-10,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,,,,,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp143784_c0_seq17,3714,46.0151,0.61862988,0,0,,4.00E-07,Q80TH2,Protein LAP2 (Densin-180-like protein) (Erbb2-interacting protein) (Erbin),Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2),GO:0016323; GO:0030056; GO:0031965; GO:0006605,basolateral plasma membrane; hemidesmosome; nuclear membrane; protein targeting,PF13855;PF00595;,3.00E-54,CHOYP_ISCW_ISCW019590.1.1,,,,,,,LAP2_MOUSE,Mus musculus (Mouse),cellular response to tumor necrosis factor [GO:0071356]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165] comp143784_c0_seq18,3706,45.9525,0.63145326,0,0,,7.00E-25,Q5PYH7,Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93),Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93),GO:0010923; GO:0050808; GO:0007268,negative regulation of phosphatase activity; synapse organization; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,,,,,,,,,DLG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808] comp143784_c0_seq2,3750,45.9467,0.62462334,0,0,,5.00E-73,Q4H4B6,Protein scribble homolog (Scribble1),Protein scribble homolog (Scribble1),GO:0032863; GO:0060561; GO:0008283; GO:0005913; GO:0016337; GO:0060027; GO:0005737; GO:0035089; GO:0000132; GO:0045930; GO:0001764; GO:0005886; GO:0050918; GO:0043065; GO:0014021,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; cell proliferation; cell-cell adherens junction; cell-cell adhesion; convergent extension involved in gastrulation; cytoplasm; establishment of apical/basal cell polarity; establishment of mitotic spindle orientation; negative regulation of mitotic cell cycle; neuron migration; plasma membrane; positive chemotaxis; positive regulation of apoptotic process; secondary neural tube formation,PF13855;PF00595;,,,,,,,,,SCRIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944] comp143784_c0_seq3,2563,47.0542,0.680407,7,0,,5.00E-25,Q5PYH7,Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93),Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93),GO:0010923; GO:0050808; GO:0007268,negative regulation of phosphatase activity; synapse organization; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,2.00E-54,CHOYP_ISCW_ISCW019590.1.1,,,,,,,DLG2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808] comp143784_c0_seq4,2542,47.1676,0.68948747,0,0,,4.00E-74,Q4H4B6,Protein scribble homolog (Scribble1),Protein scribble homolog (Scribble1),GO:0032863; GO:0060561; GO:0008283; GO:0005913; GO:0016337; GO:0060027; GO:0005737; GO:0035089; GO:0000132; GO:0045930; GO:0001764; GO:0005886; GO:0050918; GO:0043065; GO:0014021,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; cell proliferation; cell-cell adherens junction; cell-cell adhesion; convergent extension involved in gastrulation; cytoplasm; establishment of apical/basal cell polarity; establishment of mitotic spindle orientation; negative regulation of mitotic cell cycle; neuron migration; plasma membrane; positive chemotaxis; positive regulation of apoptotic process; secondary neural tube formation,PF13855;PF00595;,2.00E-54,CHOYP_LOC100866332.1.1,,,,,,,SCRIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944] comp143784_c0_seq5,3846,46.5679,0.64977584,0,0,,7.00E-24,Q6R005,Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95),Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95),GO:0030054; GO:0014069; GO:0045211; GO:0050808; GO:0007268,cell junction; postsynaptic density; postsynaptic membrane; synapse organization; synaptic transmission,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,4.00E-54,CHOYP_LOC100877438.2.2,,,,,,,DLG4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808] comp143784_c0_seq6,3912,46.3701,0.65388495,0,0,,4.00E-07,Q80TH2,Protein LAP2 (Densin-180-like protein) (Erbb2-interacting protein) (Erbin),Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2),GO:0016323; GO:0030056; GO:0031965; GO:0006605,basolateral plasma membrane; hemidesmosome; nuclear membrane; protein targeting,PF13855;PF00595;,,,,,,,,,LAP2_MOUSE,Mus musculus (Mouse),cellular response to tumor necrosis factor [GO:0071356]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165] comp143784_c0_seq7,3891,46.4405,0.65531553,0,0,,6.00E-73,Q4H4B6,Protein scribble homolog (Scribble1),Protein scribble homolog (Scribble1),GO:0032863; GO:0060561; GO:0008283; GO:0005913; GO:0016337; GO:0060027; GO:0005737; GO:0035089; GO:0000132; GO:0045930; GO:0001764; GO:0005886; GO:0050918; GO:0043065; GO:0014021,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; cell proliferation; cell-cell adherens junction; cell-cell adhesion; convergent extension involved in gastrulation; cytoplasm; establishment of apical/basal cell polarity; establishment of mitotic spindle orientation; negative regulation of mitotic cell cycle; neuron migration; plasma membrane; positive chemotaxis; positive regulation of apoptotic process; secondary neural tube formation,PF13855;PF00595;,4.00E-54,CHOYP_LOC100877438.2.2,,,,,,,SCRIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944] comp143784_c0_seq9,3702,46.0292,0.62012211,0,0,,3.00E-10,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,3.00E-54,CHOYP_ISCW_ISCW019590.1.1,,,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp143784_c1_seq1,1681,47.3528,0.74641156,37,1,,3.00E-23,Q15404,Ras suppressor protein 1 (RSP-1) (Rsu-1),Ras suppressor protein 1 (RSP-1) (Rsu-1),GO:0007265; GO:0034329; GO:0005829; GO:0007165,Ras protein signal transduction; cell junction assembly; cytosol; signal transduction,PF13855;,,,,,,,,,RSU1_HUMAN,Homo sapiens (Human),positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] comp143784_c1_seq2,2367,47.0215,0.79218946,142,76,,1.00E-148,Q4H4B6,Protein scribble homolog (Scribble1),Protein scribble homolog (Scribble1),GO:0032863; GO:0060561; GO:0008283; GO:0005913; GO:0016337; GO:0060027; GO:0005737; GO:0035089; GO:0000132; GO:0045930; GO:0001764; GO:0005886; GO:0050918; GO:0043065; GO:0014021,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; cell proliferation; cell-cell adherens junction; cell-cell adhesion; convergent extension involved in gastrulation; cytoplasm; establishment of apical/basal cell polarity; establishment of mitotic spindle orientation; negative regulation of mitotic cell cycle; neuron migration; plasma membrane; positive chemotaxis; positive regulation of apoptotic process; secondary neural tube formation,PF13855;PF00595;,1.00E-126,CHOYP_LOC100877438.2.2,,,,,,,SCRIB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944] comp143784_c1_seq3,689,44.2671,0.98214493,43,0,,2.00E-09,Q7XA40,Putative disease resistance protein RGA3 (Blight resistance protein B149) (RGA1-blb),Putative disease resistance protein RGA3 (Blight resistance protein B149) (RGA1-blb),GO:0043531; GO:0005524; GO:0006952,ADP binding; ATP binding; defense response,PF13855;PF00931;,,,,,,,,,RGA3_SOLBU,Solanum bulbocastanum (Wild potato),defense response [GO:0006952] comp143786_c1_seq1,2344,36.3481,0.41516603,2583,5499,,4.00E-107,A8H0U0,Malate dehydrogenase (EC 1.1.1.37),Malate dehydrogenase (EC 1.1.1.37),GO:0030060; GO:0044262; GO:0006108; GO:0006099,L-malate dehydrogenase activity; cellular carbohydrate metabolic process; malate metabolic process; tricarboxylic acid cycle,PF02866;PF00056;,2.00E-81,CHOYP_MDHM.1.1,9.00E-127,ruditapes_c18346,,,,,MDH_SHEPA,Shewanella pealeana (strain ATCC 700345 / ANG-SQ1),carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] comp143786_c1_seq2,2394,36.1738,0.43577155,1334,4198,,2.00E-158,Q32LG3,"Malate dehydrogenase, mitochondrial (EC 1.1.1.37)","Malate dehydrogenase, mitochondrial (EC 1.1.1.37)",GO:0030060; GO:0044262; GO:0006475; GO:0006108; GO:0005759; GO:0006099,L-malate dehydrogenase activity; cellular carbohydrate metabolic process; internal protein amino acid acetylation; malate metabolic process; mitochondrial matrix; tricarboxylic acid cycle,PF02866;PF00056;,7.00E-80,CHOYP_MDHM.1.1,5.00E-48,ruditapes2_c835,,,,,MDHM_BOVIN,Bos taurus (Bovine),carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] comp143787_c0_seq2,585,43.7607,0.86367238,5,10,,5.00E-12,P52556,Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR),Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR),GO:0004074; GO:0005829; GO:0042167; GO:0005634; GO:0005886; GO:0042602,biliverdin reductase activity; cytosol; heme catabolic process; nucleus; plasma membrane; riboflavin reductase (NADPH) activity,PF13460;,,,,,,,,,BLVRB_BOVIN,Bos taurus (Bovine),heme catabolic process [GO:0042167] comp143787_c0_seq5,494,45.749,0.73938982,12,46,,1.00E-12,P52556,Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR),Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR),GO:0004074; GO:0005829; GO:0042167; GO:0005634; GO:0005886; GO:0042602,biliverdin reductase activity; cytosol; heme catabolic process; nucleus; plasma membrane; riboflavin reductase (NADPH) activity,PF13460;,,,4.00E-22,ruditapes_c16980,,,,,BLVRB_BOVIN,Bos taurus (Bovine),heme catabolic process [GO:0042167] comp143787_c0_seq6,579,43.3506,0.81481725,31,66,,5.00E-11,P71037,Uncharacterized protein YwnB,Uncharacterized protein YwnB,,,PF13460;,,,,,,,,,YWNB_BACSU,Bacillus subtilis (strain 168), comp143791_c0_seq1,2600,41.3462,0.40918536,3,12,,4.00E-130,Q3SWZ7,Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein encoded by RNA antisense to p53),Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD repeat-containing protein WRAP53) (WD40 repeat-containing protein antisense to TP53 gene),GO:0015030; GO:0003723; GO:0005737; GO:0051973; GO:0005697; GO:0032203,Cajal body; RNA binding; cytoplasm; positive regulation of telomerase activity; telomerase holoenzyme complex; telomere formation via telomerase,PF00400;,1.00E-64,CHOYP_LOC100370874.1.1,,,,,,,WAP53_BOVIN,Bos taurus (Bovine),positive regulation of telomerase activity [GO:0051973]; telomere formation via telomerase [GO:0032203] comp143791_c0_seq2,2585,41.2766,0.42251606,1,12,,3.00E-130,Q3SWZ7,Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein encoded by RNA antisense to p53),Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD repeat-containing protein WRAP53) (WD40 repeat-containing protein antisense to TP53 gene),GO:0015030; GO:0003723; GO:0005737; GO:0051973; GO:0005697; GO:0032203,Cajal body; RNA binding; cytoplasm; positive regulation of telomerase activity; telomerase holoenzyme complex; telomere formation via telomerase,PF00400;,1.00E-64,CHOYP_LOC100370874.1.1,,,,,,,WAP53_BOVIN,Bos taurus (Bovine),positive regulation of telomerase activity [GO:0051973]; telomere formation via telomerase [GO:0032203] comp143793_c0_seq2,861,39.1405,0.58177117,19,96,,3.00E-25,P19525,"Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)","Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)",GO:0005524; GO:0000186; GO:0005829; GO:0051607; GO:0003725; GO:0030968; GO:0004694; GO:0030683; GO:0045087; GO:0019054; GO:0033689; GO:0017148; GO:0045071; GO:0004715; GO:0005634; GO:0018108; GO:0048471; GO:0051092; GO:1901224; GO:0032722; GO:0032874; GO:0046777; GO:0008601; GO:1900225; GO:1901532; GO:1902036; GO:1902033; GO:0035455; GO:0009615; GO:0006351; GO:0006412; GO:0019058; GO:0006926,"ATP binding; activation of MAPKK activity; cytosol; defense response to virus; double-stranded RNA binding; endoplasmic reticulum unfolded protein response; eukaryotic translation initiation factor 2alpha kinase activity; evasion or tolerance by virus of host immune response; innate immune response; modulation by virus of host process; negative regulation of osteoblast proliferation; negative regulation of translation; negative regulation of viral genome replication; non-membrane spanning protein tyrosine kinase activity; nucleus; peptidyl-tyrosine phosphorylation; perinuclear region of cytoplasm; positive regulation of NF-kappaB transcription factor activity; positive regulation of NIK/NF-kappaB cascade; positive regulation of chemokine production; positive regulation of stress-activated MAPK cascade; protein autophosphorylation; protein phosphatase type 2A regulator activity; regulation of NLRP3 inflammasome complex assembly; regulation of hematopoietic progenitor cell differentiation; regulation of hematopoietic stem cell differentiation; regulation of hematopoietic stem cell proliferation; response to interferon-alpha; response to virus; transcription, DNA-dependent; translation; viral life cycle; virus-infected cell apoptotic process",PF00035;PF00069;,,,,,,,,,E2AK2_HUMAN,Homo sapiens (Human),"activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; evasion or tolerance by virus of host immune response [GO:0030683]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to exogenous dsRNA [GO:0043330]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]" comp143793_c0_seq3,840,38.8095,1.15875853,34,69,,7.00E-06,Q54ZN3,Probable protein kinase DDB_G0277539 (EC 2.7.11.1),Probable protein kinase DDB_G0277539 (EC 2.7.11.1),GO:0005524; GO:0046872; GO:0005634; GO:0004674; GO:0004713; GO:0051726,ATP binding; metal ion binding; nucleus; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of cell cycle,PF00069;,,,,,,,,,Y0004_DICDI,Dictyostelium discoideum (Slime mold), comp143793_c0_seq4,796,38.0653,0.52443494,66,62,,2.00E-33,Q9Z1Z1,Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase),Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase),GO:0005524; GO:0006983; GO:0005623; GO:0031018; GO:0005789; GO:0030968; GO:0004694; GO:0016021; GO:0032057; GO:0001503; GO:0046777; GO:0051260,ATP binding; ER overload response; cell; endocrine pancreas development; endoplasmic reticulum membrane; endoplasmic reticulum unfolded protein response; eukaryotic translation initiation factor 2alpha kinase activity; integral to membrane; negative regulation of translational initiation in response to stress; ossification; protein autophosphorylation; protein homooligomerization,PF00069;,,,,,,,,,E2AK3_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; negative regulation of translation in response to stress [GO:0032055]; ossification [GO:0001503]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737] comp143794_c0_seq10,1913,38.8395,0.38899061,93,27,,3.00E-14,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,,,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143794_c0_seq6,202,47.5248,0.44754183,3,0,,2.00E-35,Q80YV3,Transformation/transcription domain-associated protein (Tra1 homolog),Transformation/transcription domain-associated protein (Tra1 homolog),GO:0035267; GO:0043968; GO:0043967; GO:0007093; GO:0016773; GO:0006355; GO:0003713; GO:0005667; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitotic cell cycle checkpoint; phosphotransferase activity, alcohol group as acceptor; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent",PF02259;PF00454;,4.00E-38,CHOYP_LOC100123553.1.1,,,,,,,TRRAP_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143794_c0_seq9,771,43.8392,0.45952458,2,4,,,,,,,,,1.00E-13,CHOYP_LOC100123553.1.1,,,,,,,,, comp143795_c1_seq1,2594,41.9429,0.56239024,33,101,,3.00E-169,O75694,Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155),Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155),GO:0005975; GO:0019221; GO:0015758; GO:0006406; GO:0007077; GO:0005635; GO:0031965; GO:0005643; GO:0006606; GO:0086014; GO:0010827; GO:0044281; GO:0017056; GO:0055085; GO:0005215; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; mRNA export from nucleus; mitotic nuclear envelope disassembly; nuclear envelope; nuclear membrane; nuclear pore; protein import into nucleus; regulation of atrial cardiac muscle cell action potential; regulation of glucose transport; small molecule metabolic process; structural constituent of nuclear pore; transmembrane transport; transporter activity; viral process,PF03177;PF08801;,,,,,,,,,NU155_HUMAN,Homo sapiens (Human),atrial cardiac muscle cell action potential [GO:0086014]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear envelope organization [GO:0006998]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; protein targeting to nuclear inner membrane [GO:0036228]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp143795_c1_seq4,2308,40.5979,0.55933554,7,16,,5.00E-132,P37199,Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155) (P140),Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155) (P140),GO:0005737; GO:0051028; GO:0005635; GO:0031965; GO:0005643; GO:0006913; GO:0015031; GO:0017056,cytoplasm; mRNA transport; nuclear envelope; nuclear membrane; nuclear pore; nucleocytoplasmic transport; protein transport; structural constituent of nuclear pore,PF03177;PF08801;,9.00E-91,CHOYP_BRAFLDRAFT_225253.1.1,,,,,,,NU155_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]; protein targeting to nuclear inner membrane [GO:0036228]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] comp143795_c1_seq5,1568,47.8316,0.40176702,16,9,,,,,,,,,2.00E-85,CHOYP_BRAFLDRAFT_225253.1.1,,,,,,,,, comp143797_c0_seq1,4207,45.9948,0.59911601,287,1307,,1.00E-107,Q21313,Laminin-like protein epi-1,Laminin-like protein epi-1,GO:0007414; GO:0005604; GO:0071711; GO:0007155; GO:0001764; GO:0010950; GO:0040017; GO:0042127; GO:0000003; GO:0009408; GO:0051788,axonal defasciculation; basement membrane; basement membrane organization; cell adhesion; neuron migration; positive regulation of endopeptidase activity; positive regulation of locomotion; regulation of cell proliferation; reproduction; response to heat; response to misfolded protein,PF00052;PF00053;PF00054;PF02210;PF06009;PF00055;,6.00E-14,CHOYP_LOC100875585.1.1,,,,,,,EPI1_CAEEL,Caenorhabditis elegans,axonal defasciculation [GO:0007414]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; neuron migration [GO:0001764]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of locomotion [GO:0040017]; regulation of cell proliferation [GO:0042127]; reproduction [GO:0000003]; response to heat [GO:0009408]; response to misfolded protein [GO:0051788] comp143798_c0_seq2,1429,44.3667,0.44792278,0,0,,1.00E-28,Q03468,DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),GO:0005524; GO:0003677; GO:0008094; GO:0007256; GO:0007257; GO:0006284; GO:0003682; GO:0004386; GO:0008630; GO:0035264; GO:0005730; GO:0045494; GO:0032786; GO:0032403; GO:0006290; GO:0009411; GO:0010224; GO:0010165; GO:0010332; GO:0006979; GO:0000303; GO:0009636; GO:0008023; GO:0006366; GO:0006283,"ATP binding; DNA binding; DNA-dependent ATPase activity; activation of JNKK activity; activation of JUN kinase activity; base-excision repair; chromatin binding; helicase activity; intrinsic apoptotic signaling pathway in response to DNA damage; multicellular organism growth; nucleolus; photoreceptor cell maintenance; positive regulation of DNA-dependent transcription, elongation; protein complex binding; pyrimidine dimer repair; response to UV; response to UV-B; response to X-ray; response to gamma radiation; response to oxidative stress; response to superoxide; response to toxic substance; transcription elongation factor complex; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF00271;PF00176;,1.00E-98,CHOYP_ATRX.1.1,,,,,,,ERCC6_HUMAN,Homo sapiens (Human),"activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]" comp143798_c0_seq3,3396,43.3746,0.45592773,9,28,,9.00E-134,P46100,Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX),Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX),GO:0005524; GO:0003677; GO:0003678; GO:0006306; GO:0006310; GO:0006281; GO:0003682; GO:0030900; GO:0005720; GO:0006355; GO:0008270,"ATP binding; DNA binding; DNA helicase activity; DNA methylation; DNA recombination; DNA repair; chromatin binding; forebrain development; nuclear heterochromatin; regulation of transcription, DNA-dependent; zinc ion binding",PF00271;PF00176;,,,,,,,,,ATRX_HUMAN,Homo sapiens (Human),"cellular response to hydroxyurea [GO:0072711]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA methylation [GO:0006306]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication-independent nucleosome assembly [GO:0006336]; forebrain development [GO:0030900]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901581]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of histone H3-K9 trimethylation [GO:1900112]; regulation of transcription, DNA-templated [GO:0006355]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp143798_c0_seq5,3116,35.4942,0.41964586,204,338,,1.00E-33,P82798,Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Fragment),Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Fragment),GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0005634; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; nucleus; zinc ion binding,,,,8.00E-15,ruditapes_s38575,,,,,ATRX_MACEU,Macropus eugenii (Tammar wallaby),"cellular response to hydroxyurea [GO:0072711]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901581]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of histone H3-K9 trimethylation [GO:1900112]; replication fork processing [GO:0031297]; transcription, DNA-templated [GO:0006351]" comp143798_c0_seq7,3202,43.5353,0.45740763,13,10,,3.00E-134,Q7YQM4,Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP),Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP),GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0005634; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; nucleus; zinc ion binding,PF00271;PF00176;,2.00E-95,CHOYP_ATRX.1.1,,,,,,,ATRX_PANTR,Pan troglodytes (Chimpanzee),"cellular response to hydroxyurea [GO:0072711]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901581]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of histone H3-K9 trimethylation [GO:1900112]; replication fork processing [GO:0031297]; transcription, DNA-templated [GO:0006351]" comp143799_c0_seq1,838,47.0167,0.45096681,29,87,,,,,,,,,2.00E-100,CHOYP_LOC591290.1.3,,,,,,,,, comp143799_c1_seq1,2215,42.4379,0.37525122,46,562,,4.00E-99,A3KN83,Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3),Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3),GO:0006355,"regulation of transcription, DNA-dependent",PF13871;,2.00E-136,CHOYP_LOC591290.3.3,,,,,,,SBNO1_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]" comp143799_c3_seq1,1056,44.697,0.3488452,35,85,,1.00E-66,Q5F371,Protein strawberry notch homolog 1,Protein strawberry notch homolog 1,GO:0006355,"regulation of transcription, DNA-dependent",PF13871;,9.00E-119,CHOYP_LOC591290.1.3,,,,,,,SBNO1_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]" comp143801_c0_seq1,2338,42.8571,0.4612095,342,1676,,0,Q9D0R2,"Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)","Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)",GO:0005524; GO:0005737; GO:0004829; GO:0006435,ATP binding; cytoplasm; threonine-tRNA ligase activity; threonyl-tRNA aminoacylation,PF03129;PF02824;PF00587;PF07973;,0,CHOYP_SYTC.1.1,6.00E-110,ruditapes_c19986,,,,,SYTC_MOUSE,Mus musculus (Mouse),threonyl-tRNA aminoacylation [GO:0006435] comp143803_c0_seq1,4551,34.6078,0.43873196,0,0,,5.00E-44,A4FW92,Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,,,,,,,,,PURA_METM5,Methanococcus maripaludis (strain C5 / ATCC BAA-1333),'de novo' AMP biosynthetic process [GO:0044208] comp143803_c0_seq2,4566,34.6693,0.43593757,19,46,,4.00E-178,Q7ZY87,"Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)","Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)",GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,5.00E-110,CHOYP_PUA1A.1.1,,,,,,,PURA2_XENLA,Xenopus laevis (African clawed frog),'de novo' AMP biosynthetic process [GO:0044208] comp143803_c0_seq3,4587,34.7068,0.44729143,9,29,,5.00E-44,A4FW92,Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,,,,,,,,,PURA_METM5,Methanococcus maripaludis (strain C5 / ATCC BAA-1333),'de novo' AMP biosynthetic process [GO:0044208] comp143803_c0_seq4,4575,34.6448,0.4499291,0,0,,4.00E-178,Q7ZY87,"Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)","Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)",GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,5.00E-110,CHOYP_PUA1A.1.1,,,,,,,PURA2_XENLA,Xenopus laevis (African clawed frog),'de novo' AMP biosynthetic process [GO:0044208] comp143804_c0_seq2,1621,39.2967,0.73384838,159,384,,4.00E-13,Q8BXK9,Chloride intracellular channel protein 5,Chloride intracellular channel protein 5,GO:0005794; GO:0015629; GO:0060088; GO:0034707; GO:0002024; GO:0005815; GO:0050885; GO:0008104; GO:0007605; GO:0032420; GO:0005247,Golgi apparatus; actin cytoskeleton; auditory receptor cell stereocilium organization; chloride channel complex; diet induced thermogenesis; microtubule organizing center; neuromuscular process controlling balance; protein localization; sensory perception of sound; stereocilium; voltage-gated chloride channel activity,PF13417;,,,2.00E-88,ruditapes_c10727,,,,,CLIC5_MOUSE,Mus musculus (Mouse),auditory receptor cell stereocilium organization [GO:0060088]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; diet induced thermogenesis [GO:0002024]; neuromuscular process controlling balance [GO:0050885]; protein localization [GO:0008104]; response to dietary excess [GO:0002021]; sensory perception of sound [GO:0007605] comp143804_c2_seq1,493,42.5963,0.63304608,20,0,,1.00E-23,Q8BUL6,Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1),Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1),GO:0050853; GO:0033327; GO:0008209; GO:0070301; GO:0005737; GO:0045184; GO:0008210; GO:0060325; GO:0001553; GO:0035264; GO:0051898; GO:0005634; GO:0060021; GO:0014065; GO:0043325; GO:0048008; GO:0009791; GO:0032587; GO:0031529; GO:0048705; GO:0007283,"B cell receptor signaling pathway; Leydig cell differentiation; androgen metabolic process; cellular response to hydrogen peroxide; cytoplasm; establishment of protein localization; estrogen metabolic process; face morphogenesis; luteinization; multicellular organism growth; negative regulation of protein kinase B signaling cascade; nucleus; palate development; phosphatidylinositol 3-kinase cascade; phosphatidylinositol-3,4-bisphosphate binding; platelet-derived growth factor receptor signaling pathway; post-embryonic development; ruffle membrane; ruffle organization; skeletal system morphogenesis; spermatogenesis",PF00169;,,,2.00E-25,ruditapes_c24265,,,,,PKHA1_MOUSE,Mus musculus (Mouse),androgen metabolic process [GO:0008209]; B cell receptor signaling pathway [GO:0050853]; cellular response to hydrogen peroxide [GO:0070301]; establishment of protein localization [GO:0045184]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; multicellular organism growth [GO:0035264]; negative regulation of protein kinase B signaling [GO:0051898]; palate development [GO:0060021]; phosphatidylinositol 3-kinase signaling [GO:0014065]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; ruffle organization [GO:0031529]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283] comp143805_c0_seq1,8707,38.3829,0.57371977,1796,6133,,0,P49951,Clathrin heavy chain 1,Clathrin heavy chain 1,GO:0030132; GO:0030130; GO:0006886; GO:0042470; GO:0030117; GO:0005739; GO:0005198; GO:0016192,clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; intracellular protein transport; melanosome; membrane coat; mitochondrion; structural molecule activity; vesicle-mediated transport,PF00637;PF09268;PF01394;,0,CHOYP_CLH1.2.2,,,,,,,CLHC1_BOVIN,Bos taurus (Bovine),intracellular protein transport [GO:0006886]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; vesicle-mediated transport [GO:0016192] comp143805_c0_seq2,7700,39.7403,0.58168548,0,55,,0,P49951,Clathrin heavy chain 1,Clathrin heavy chain 1,GO:0030132; GO:0030130; GO:0006886; GO:0042470; GO:0030117; GO:0005739; GO:0005198; GO:0016192,clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; intracellular protein transport; melanosome; membrane coat; mitochondrion; structural molecule activity; vesicle-mediated transport,PF00637;PF09268;PF01394;,0,CHOYP_CLH1.2.2,,,,,,,CLHC1_BOVIN,Bos taurus (Bovine),intracellular protein transport [GO:0006886]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; vesicle-mediated transport [GO:0016192] comp143806_c1_seq1,2446,31.807,1.01877495,19,23,,3.00E-07,O95150,"Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]","Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]",GO:0007250; GO:0006919; GO:0042107; GO:0005615; GO:0006955; GO:0005887; GO:0050715; GO:0005102,activation of NF-kappaB-inducing kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; cytokine metabolic process; extracellular space; immune response; integral to plasma membrane; positive regulation of cytokine secretion; receptor binding,PF00229;,,,,,,,,,TNF15_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp143806_c1_seq3,2490,32.0482,1.06398846,8,19,,3.00E-07,O95150,"Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]","Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]",GO:0007250; GO:0006919; GO:0042107; GO:0005615; GO:0006955; GO:0005887; GO:0050715; GO:0005102,activation of NF-kappaB-inducing kinase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; cytokine metabolic process; extracellular space; immune response; integral to plasma membrane; positive regulation of cytokine secretion; receptor binding,PF00229;,,,,,,,,,TNF15_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp143809_c0_seq3,497,35.2113,0.06530318,33,269,,8.00E-61,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp143811_c0_seq2,2855,36.8126,0.39535177,12,71,,6.00E-40,Q496Z9,TRMT1-like protein (EC 2.1.1.-),TRMT1-like protein (EC 2.1.1.-),GO:0007610; GO:0046872; GO:0004809; GO:0000049,behavior; metal ion binding; tRNA (guanine-N2-)-methyltransferase activity; tRNA binding,PF02005;,,,,,,,,,TRM1L_RAT,Rattus norvegicus (Rat),behavior [GO:0007610]; tRNA processing [GO:0008033] comp143811_c0_seq3,2864,36.6969,0.38593871,15,142,,4.00E-40,Q496Z9,TRMT1-like protein (EC 2.1.1.-),TRMT1-like protein (EC 2.1.1.-),GO:0007610; GO:0046872; GO:0004809; GO:0000049,behavior; metal ion binding; tRNA (guanine-N2-)-methyltransferase activity; tRNA binding,PF02005;,,,,,,,,,TRM1L_RAT,Rattus norvegicus (Rat),behavior [GO:0007610]; tRNA processing [GO:0008033] comp143811_c0_seq4,746,42.7614,0.3264866,0,10,,7.00E-11,Q58356,"tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)","tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)",GO:0004809; GO:0000049,tRNA (guanine-N2-)-methyltransferase activity; tRNA binding,PF02005;,,,,,,,,,TRM1_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),tRNA N2-guanine methylation [GO:0002940] comp143813_c0_seq1,6204,46.7118,0.49995353,185,26,,0,A0JM13,C2 domain-containing protein 3,C2 domain-containing protein 3,GO:0005814; GO:0005929; GO:0005932; GO:0035058,centriole; cilium; microtubule basal body; nonmotile primary cilium assembly,PF00168;,,,,,,,,,C2CD3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),centriole elongation [GO:0061511]; nonmotile primary cilium assembly [GO:0035058]; protein localization to centrosome [GO:0071539] comp143813_c0_seq2,3446,47.6204,0.45235685,17,0,,1.00E-136,Q52KB6,C2 domain-containing protein 3 (Protein hearty),C2 domain-containing protein 3 (Protein hearty),GO:0007420; GO:0005814; GO:0036064; GO:0042733; GO:0001947; GO:0001701; GO:0021997; GO:0021915; GO:0035058; GO:0016485; GO:0030162; GO:0008589,brain development; centriole; cilium basal body; embryonic digit morphogenesis; heart looping; in utero embryonic development; neural plate axis specification; neural tube development; nonmotile primary cilium assembly; protein processing; regulation of proteolysis; regulation of smoothened signaling pathway,PF00168;,3.00E-131,CHOYP_LOC576341.1.2,,,,,,,C2CD3_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; centriole elongation [GO:0061511]; cilium assembly [GO:0042384]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; neural plate axis specification [GO:0021997]; neural tube development [GO:0021915]; nonmotile primary cilium assembly [GO:0035058]; pattern specification process [GO:0007389]; protein localization to centrosome [GO:0071539]; protein processing [GO:0016485]; regulation of proteolysis [GO:0030162]; regulation of smoothened signaling pathway [GO:0008589] comp143813_c0_seq3,3254,48.0025,0.45569318,10,0,,7.00E-154,A0JM13,C2 domain-containing protein 3,C2 domain-containing protein 3,GO:0005814; GO:0005929; GO:0005932; GO:0035058,centriole; cilium; microtubule basal body; nonmotile primary cilium assembly,PF00168;,2.00E-131,CHOYP_LOC576341.1.2,,,,,,,C2CD3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),centriole elongation [GO:0061511]; nonmotile primary cilium assembly [GO:0035058]; protein localization to centrosome [GO:0071539] comp143814_c2_seq2,2905,40.4131,0.50122642,29,20,,3.00E-36,A2AM05,Centlein (Centrosomal protein),Centlein (Centrosomal protein),GO:0005814,centriole,,,,,,,,,,CNTLN_MOUSE,Mus musculus (Mouse),centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365] comp143814_c2_seq3,3928,42.1079,0.54038026,214,161,,6.00E-36,A2AM05,Centlein (Centrosomal protein),Centlein (Centrosomal protein),GO:0005814,centriole,,2.00E-33,CHOYP_LOC100377658.1.1,,,,,,,CNTLN_MOUSE,Mus musculus (Mouse),centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365] comp143814_c2_seq5,456,41.4474,0.58291097,0,0,,,,,,,,,4.00E-11,CHOYP_LOC100377658.1.1,,,,,,,,, comp143815_c0_seq1,2872,45.0209,0.57001183,0,50,,0,Q94887,Neurexin-4 (Neurexin IV),Neurexin-4 (Neurexin IV),GO:0008366; GO:0061343; GO:0007391; GO:0060857; GO:0007163; GO:0003015; GO:0005887; GO:0021682; GO:0005919; GO:0048786; GO:0097105; GO:0008104; GO:0035151; GO:0019991; GO:0008039; GO:0016081; GO:0016080; GO:0072553,"axon ensheathment; cell adhesion involved in heart morphogenesis; dorsal closure; establishment of glial blood-brain barrier; establishment or maintenance of cell polarity; heart process; integral to plasma membrane; nerve maturation; pleated septate junction; presynaptic active zone; presynaptic membrane assembly; protein localization; regulation of tube size, open tracheal system; septate junction assembly; synaptic target recognition; synaptic vesicle docking involved in exocytosis; synaptic vesicle targeting; terminal button organization",PF00008;PF00754;PF02210;,,,,,,,,,NRX4_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of cell polarity [GO:0007163]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; synaptic vesicle docking [GO:0016081]; synaptic vesicle targeting [GO:0016080]; terminal button organization [GO:0072553]" comp143815_c0_seq2,2859,45.2256,0.5598924,0,46,,1.00E-29,Q9ULB1,Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha),Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha),GO:0033130; GO:0030534; GO:0007411; GO:0005246; GO:0005509; GO:0007155; GO:0050839; GO:0030054; GO:0009986; GO:0030198; GO:0097116; GO:0005887; GO:0007612; GO:0097118; GO:0097109; GO:0050885; GO:0007269; GO:2000463; GO:0051965; GO:0090129; GO:0051968; GO:0097119; GO:0097104; GO:0060134; GO:0042734; GO:0004872; GO:2000821; GO:0035176; GO:0071625,"acetylcholine receptor binding; adult behavior; axon guidance; calcium channel regulator activity; calcium ion binding; cell adhesion; cell adhesion molecule binding; cell junction; cell surface; extracellular matrix organization; gephyrin clustering; integral to plasma membrane; learning; neuroligin clustering; neuroligin family protein binding; neuromuscular process controlling balance; neurotransmitter secretion; positive regulation of excitatory postsynaptic membrane potential; positive regulation of synapse assembly; positive regulation of synapse maturation; positive regulation of synaptic transmission, glutamatergic; postsynaptic density protein 95 clustering; postsynaptic membrane assembly; prepulse inhibition; presynaptic membrane; receptor activity; regulation of grooming behavior; social behavior; vocalization behavior",PF00008;PF00054;PF02210;PF01034;,,,,,,,,,NRX1A_HUMAN,Homo sapiens (Human),"adult behavior [GO:0030534]; axon guidance [GO:0007411]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; regulation of grooming behavior [GO:2000821]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]; vocal learning [GO:0042297]" comp143815_c0_seq3,1004,42.0319,0.45293778,8,287,,,,,,,,,4.00E-47,CHOYP_NRX4.1.1,,,,,,,,, comp143815_c0_seq5,1152,48.3507,0.57276969,2,32,,3.00E-73,Q94887,Neurexin-4 (Neurexin IV),Neurexin-4 (Neurexin IV),GO:0008366; GO:0061343; GO:0007391; GO:0060857; GO:0007163; GO:0003015; GO:0005887; GO:0021682; GO:0005919; GO:0048786; GO:0097105; GO:0008104; GO:0035151; GO:0019991; GO:0008039; GO:0016081; GO:0016080; GO:0072553,"axon ensheathment; cell adhesion involved in heart morphogenesis; dorsal closure; establishment of glial blood-brain barrier; establishment or maintenance of cell polarity; heart process; integral to plasma membrane; nerve maturation; pleated septate junction; presynaptic active zone; presynaptic membrane assembly; protein localization; regulation of tube size, open tracheal system; septate junction assembly; synaptic target recognition; synaptic vesicle docking involved in exocytosis; synaptic vesicle targeting; terminal button organization",PF00008;PF00754;PF02210;,,,,,,,,,NRX4_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of cell polarity [GO:0007163]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; synaptic vesicle docking [GO:0016081]; synaptic vesicle targeting [GO:0016080]; terminal button organization [GO:0072553]" comp143815_c1_seq1,229,38.8646,0.83681429,0,9,,2.00E-11,Q9W6R5,Retinoschisin (X-linked juvenile retinoschisis protein homolog),Retinoschisin (X-linked juvenile retinoschisis protein homolog),GO:0007155; GO:0005576,cell adhesion; extracellular region,PF00754;,,,,,,,,,XLRS1_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),cell adhesion [GO:0007155] comp143817_c0_seq1,580,39.1379,0.90343917,82,10,,9.00E-63,Q9GZV8,PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14),PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14),GO:0003677; GO:0001708; GO:0000902; GO:0009566; GO:0007281; GO:0048873; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell fate specification; cell morphogenesis; fertilization; germ cell development; homeostasis of number of cells within a tissue; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,4.00E-63,CHOYP_LOC100373135.1.1,,,,,,,PRD14_HUMAN,Homo sapiens (Human),"cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of DNA methylation [GO:0044030]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]" comp143817_c2_seq1,7729,41.2214,0.5238107,46,0,,8.00E-29,Q8WWI1,LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP),LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP),GO:0005737; GO:0005634; GO:0000151; GO:0004842; GO:0008270,cytoplasm; nucleus; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding,PF00307;PF15949;PF00412;PF00595;,2.00E-36,CHOYP_LMO7.1.1,,,,,,,LMO7_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051] comp143817_c2_seq2,3759,38.3613,0.54678188,25,0,,3.00E-29,Q8WWI1,LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP),LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP),GO:0005737; GO:0005634; GO:0000151; GO:0004842; GO:0008270,cytoplasm; nucleus; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding,PF00307;PF15949;PF00412;PF00595;,,,,,,,,,LMO7_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051] comp143817_c2_seq3,7794,41.1727,0.52080086,18,0,,5.00E-27,Q3KQW7,LIM and calponin homology domains-containing protein 1,LIM and calponin homology domains-containing protein 1,GO:0031032; GO:0008270,actomyosin structure organization; zinc ion binding,PF00307;PF15949;PF00412;,,,,,,,,,LIMC1_XENLA,Xenopus laevis (African clawed frog),actomyosin structure organization [GO:0031032] comp143817_c2_seq4,6676,42.4805,0.53989247,54,14,,7.00E-29,Q8WWI1,LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP),LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP),GO:0005737; GO:0005634; GO:0000151; GO:0004842; GO:0008270,cytoplasm; nucleus; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding,PF00307;PF15949;PF00412;PF00595;,1.00E-30,CHOYP_LMO7.1.1,,,,,,,LMO7_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051] comp143818_c0_seq2,1892,48.8372,0.41060014,6,33,,9.00E-121,P20072,Annexin A7 (Annexin VII) (Annexin-7) (Synexin),Annexin A7 (Annexin VII) (Annexin-7) (Synexin),GO:0005509; GO:0005544; GO:0008283; GO:0006874; GO:0009992; GO:0042584; GO:0005829; GO:0005789; GO:0007599; GO:0005635; GO:0005886; GO:0008360; GO:0009651; GO:0035176,calcium ion binding; calcium-dependent phospholipid binding; cell proliferation; cellular calcium ion homeostasis; cellular water homeostasis; chromaffin granule membrane; cytosol; endoplasmic reticulum membrane; hemostasis; nuclear envelope; plasma membrane; regulation of cell shape; response to salt stress; social behavior,PF00191;,7.00E-22,CHOYP_ANXA6.1.2,,,,,,,ANXA7_BOVIN,Bos taurus (Bovine),autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176] comp143818_c0_seq3,2491,42.5532,0.39258152,8,73,,2.00E-115,P97429,Annexin A4 (Annexin IV) (Annexin-4),Annexin A4 (Annexin IV) (Annexin-4),GO:0016324; GO:0005509; GO:0005544; GO:0001822,apical plasma membrane; calcium ion binding; calcium-dependent phospholipid binding; kidney development,PF00191;,5.00E-113,CHOYP_LOC100561894.1.1,5.00E-16,ruditapes_c7392,,,,,ANXA4_MOUSE,Mus musculus (Mouse),epithelial cell differentiation [GO:0030855]; kidney development [GO:0001822]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp143818_c0_seq4,2571,42.9794,0.42391325,13,179,,3.00E-118,P20072,Annexin A7 (Annexin VII) (Annexin-7) (Synexin),Annexin A7 (Annexin VII) (Annexin-7) (Synexin),GO:0005509; GO:0005544; GO:0008283; GO:0006874; GO:0009992; GO:0042584; GO:0005829; GO:0005789; GO:0007599; GO:0005635; GO:0005886; GO:0008360; GO:0009651; GO:0035176,calcium ion binding; calcium-dependent phospholipid binding; cell proliferation; cellular calcium ion homeostasis; cellular water homeostasis; chromaffin granule membrane; cytosol; endoplasmic reticulum membrane; hemostasis; nuclear envelope; plasma membrane; regulation of cell shape; response to salt stress; social behavior,PF00191;,7.00E-42,CHOYP_ANXA4.2.2,,,,,,,ANXA7_BOVIN,Bos taurus (Bovine),autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176] comp143819_c0_seq1,726,42.2865,0.66091034,28,153,,,,,,,,,7.00E-36,CHOYP_AL1A1.1.1,2.00E-33,ruditapes2_c212,,,,,,, comp143819_c0_seq2,1220,46.7213,0.59576664,207,1226,,3.00E-154,P11884,"Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1)","Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1)",GO:0070404; GO:0004029; GO:0071398; GO:0032870; GO:0006068; GO:0042802; GO:0001889; GO:0005759; GO:0005739; GO:0043066; GO:0032355; GO:0055093; GO:0032496; GO:0035094; GO:0032570; GO:0033574,NADH binding; aldehyde dehydrogenase (NAD) activity; cellular response to fatty acid; cellular response to hormone stimulus; ethanol catabolic process; identical protein binding; liver development; mitochondrial matrix; mitochondrion; negative regulation of apoptotic process; response to estradiol stimulus; response to hyperoxia; response to lipopolysaccharide; response to nicotine; response to progesterone stimulus; response to testosterone stimulus,PF00171;,1.00E-40,CHOYP_AL1A1.1.1,9.00E-35,ruditapes_c266,,,,,ALDH2_RAT,Rattus norvegicus (Rat),cellular response to fatty acid [GO:0071398]; cellular response to hormone stimulus [GO:0032870]; ethanol catabolic process [GO:0006068]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; response to estradiol [GO:0032355]; response to hyperoxia [GO:0055093]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574] comp143819_c0_seq4,1531,34.03,0.75830241,51,397,,,,,,,,,,,1.00E-34,ruditapes2_c1038,,,,,,, comp143819_c0_seq7,1515,34.3894,0.7511715,29,303,,7.00E-66,Q29491,"Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)","Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)",GO:0004029; GO:0005737; GO:0006068,aldehyde dehydrogenase (NAD) activity; cytoplasm; ethanol catabolic process,PF00171;,,,4.00E-21,ruditapes_c7461,,,,,ALDH2_MACPR,Macroscelides proboscideus (Short-eared elephant shrew),ethanol catabolic process [GO:0006068] comp143820_c0_seq1,3479,46.3352,0.51924561,0,0,,,,,,,,,0,CHOYP_LOC100370750.2.2,,,,,,,,, comp143820_c0_seq3,7551,46.8282,0.5450559,295,23,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_LOC100370750.2.2,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp143820_c0_seq5,2766,46.6016,0.52218922,0,0,,4.00E-132,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_LOC100370750.2.2,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp143820_c0_seq6,715,45.5944,0.53390999,0,0,,,,,,,,,2.00E-18,CHOYP_LOC591790.1.1,,,,,,,,, comp143821_c1_seq1,786,44.402,0.45321889,67,77,,4.00E-14,Q6P1D7,Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12),Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12),GO:0048257; GO:0017108; GO:0010792; GO:0006260; GO:0070522; GO:0048476; GO:0033557; GO:0008821; GO:0000724; GO:0008047; GO:0000790; GO:0000784; GO:0006289,"3'-flap endonuclease activity; 5'-flap endonuclease activity; DNA double-strand break processing involved in repair via single-strand annealing; DNA replication; ERCC4-ERCC1 complex; Holliday junction resolvase complex; Slx1-Slx4 complex; crossover junction endodeoxyribonuclease activity; double-strand break repair via homologous recombination; enzyme activator activity; nuclear chromatin; nuclear chromosome, telomeric region; nucleotide-excision repair",PF00651;PF09494;,,,,,,,,,SLX4_MOUSE,Mus musculus (Mouse),DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656] comp143821_c2_seq6,1970,35.3299,0.54110526,0,0,,2.00E-15,Q6P1D7,Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12),Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12),GO:0048257; GO:0017108; GO:0010792; GO:0006260; GO:0070522; GO:0048476; GO:0033557; GO:0008821; GO:0000724; GO:0008047; GO:0000790; GO:0000784; GO:0006289,"3'-flap endonuclease activity; 5'-flap endonuclease activity; DNA double-strand break processing involved in repair via single-strand annealing; DNA replication; ERCC4-ERCC1 complex; Holliday junction resolvase complex; Slx1-Slx4 complex; crossover junction endodeoxyribonuclease activity; double-strand break repair via homologous recombination; enzyme activator activity; nuclear chromatin; nuclear chromosome, telomeric region; nucleotide-excision repair",PF00651;PF09494;,,,,,,,,,SLX4_MOUSE,Mus musculus (Mouse),DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656] comp143821_c3_seq3,1697,38.5386,0.45757638,22,31,,7.00E-12,Q6P1D7,Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12),Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12),GO:0048257; GO:0017108; GO:0010792; GO:0006260; GO:0070522; GO:0048476; GO:0033557; GO:0008821; GO:0000724; GO:0008047; GO:0000790; GO:0000784; GO:0006289,"3'-flap endonuclease activity; 5'-flap endonuclease activity; DNA double-strand break processing involved in repair via single-strand annealing; DNA replication; ERCC4-ERCC1 complex; Holliday junction resolvase complex; Slx1-Slx4 complex; crossover junction endodeoxyribonuclease activity; double-strand break repair via homologous recombination; enzyme activator activity; nuclear chromatin; nuclear chromosome, telomeric region; nucleotide-excision repair",PF00651;PF09494;,,,,,,,,,SLX4_MOUSE,Mus musculus (Mouse),DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656] comp143822_c0_seq1,3158,37.1754,0.40187514,270,1557,,2.00E-44,O75127,"Pentatricopeptide repeat-containing protein 1, mitochondrial","Pentatricopeptide repeat-containing protein 1, mitochondrial",GO:0005759; GO:0042780; GO:0000049,mitochondrial matrix; tRNA 3'-end processing; tRNA binding,PF13812;PF17177;,,,,,,,,,PTCD1_HUMAN,Homo sapiens (Human),tRNA 3'-end processing [GO:0042780] comp143823_c0_seq1,3672,41.7211,0.47625534,267,1351,,0,Q6NRY2,Nucleolar protein 6,Nucleolar protein 6,GO:0003723; GO:0005730,RNA binding; nucleolus,PF03813;,,,,,,,,,NOL6_XENLA,Xenopus laevis (African clawed frog), comp143823_c0_seq2,1751,41.9189,0.46869999,19,111,,4.00E-118,Q6NRY2,Nucleolar protein 6,Nucleolar protein 6,GO:0003723; GO:0005730,RNA binding; nucleolus,PF03813;,,,,,,,,,NOL6_XENLA,Xenopus laevis (African clawed frog), comp143824_c0_seq1,1859,42.6573,0.37123369,0,0,,,,,,,,,8.00E-173,CHOYP_BRAFLDRAFT_97676.1.1,,,,,,,,, comp143824_c0_seq3,1995,42.1554,0.36531695,0,0,,0,Q8N1B4,Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein),Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein),GO:0005794; GO:0010668; GO:0048611; GO:0010008; GO:0015031,Golgi apparatus; ectodermal cell differentiation; embryonic ectodermal digestive tract development; endosome membrane; protein transport,PF04129;,,,,,,,,,VPS52_HUMAN,Homo sapiens (Human),ectodermal cell differentiation [GO:0010668]; embryonic ectodermal digestive tract development [GO:0048611]; endocytic recycling [GO:0032456]; lysosomal transport [GO:0007041]; protein transport [GO:0015031] comp143824_c0_seq6,1995,42.1554,0.37692713,0,0,,7.00E-18,Q9UST3,Vacuolar protein sorting-associated protein 52,Vacuolar protein sorting-associated protein 52,GO:0000938; GO:0006896; GO:0030029; GO:0006886; GO:0016020; GO:0042147,"GARP complex; Golgi to vacuole transport; actin filament-based process; intracellular protein transport; membrane; retrograde transport, endosome to Golgi",PF04129;,0,CHOYP_BRAFLDRAFT_97676.1.1,,,,,,,VPS52_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"actin filament-based process [GO:0030029]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated transport [GO:0016192]" comp143825_c0_seq10,4027,41.2466,0.56833571,0,0,,1.00E-43,Q98931,Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B),Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B),GO:0005509; GO:0006897; GO:0016021; GO:0021517,calcium ion binding; endocytosis; integral to membrane; ventral spinal cord development,PF00057;PF00058;,8.00E-12,CHOYP_SORL.3.3,,,,,,,LRP8_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897]; ventral spinal cord development [GO:0021517] comp143825_c0_seq11,2232,42.2491,0.6044339,2,0,,3.00E-48,B8MG72,Vacuolar protein sorting/targeting protein 10 (Carboxypeptidase Y receptor) (CPY receptor) (Sortilin vps10) (Vacuolar carboxypeptidase sorting receptor vps10),Vacuolar protein sorting/targeting protein 10 (Carboxypeptidase Y receptor) (CPY receptor) (Sortilin vps10) (Vacuolar carboxypeptidase sorting receptor vps10),GO:0005794; GO:0016021; GO:0031902; GO:0015031,Golgi apparatus; integral to membrane; late endosome membrane; protein transport,PF15902;PF15901;,1.00E-13,CHOYP_SORL.3.3,,,,,,,VPS10_TALSN,Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum),protein transport [GO:0015031] comp143825_c0_seq12,525,46.0952,0.61681951,0,0,,5.00E-12,P07522,Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor],Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor],GO:0007262; GO:0005509; GO:0005154; GO:0007173; GO:0016021; GO:0043388; GO:0050708,STAT protein import into nucleus; calcium ion binding; epidermal growth factor receptor binding; epidermal growth factor receptor signaling pathway; integral to membrane; positive regulation of DNA binding; regulation of protein secretion,PF00008;PF07645;PF00058;,,,,,,,,,EGF_RAT,Rattus norvegicus (Rat),canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of protein secretion [GO:0050708]; regulation of protein transport [GO:0051223]; STAT protein import into nucleus [GO:0007262]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332] comp143825_c0_seq13,537,46.3687,0.66256387,0,0,,7.00E-08,O88322,Nidogen-2 (NID-2) (Entactin-2),Nidogen-2 (NID-2) (Entactin-2),GO:0005604; GO:0005509; GO:0009986; GO:0007160,basement membrane; calcium ion binding; cell surface; cell-matrix adhesion,PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID2_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198] comp143825_c0_seq2,4825,41.8031,0.57145566,0,0,,1.00E-65,Q91ZX7,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0005887; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0048471; GO:0010875; GO:0006898; GO:0032956; GO:0032429,aorta morphogenesis; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; integral to plasma membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; perinuclear region of cytoplasm; positive regulation of cholesterol efflux; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,3.00E-12,CHOYP_LRP2.6.7,,,,,,,LRP1_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429] comp143825_c0_seq3,2409,39.8506,0.60860981,2,8,,5.00E-07,Q53EP0,Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37),GO:0005783; GO:0016021; GO:0045600,endoplasmic reticulum; integral to membrane; positive regulation of fat cell differentiation,PF00041;,5.00E-12,CHOYP_PHUM_PHUM470230.1.1,,,,,,,FND3B_HUMAN,Homo sapiens (Human), comp143825_c0_seq4,2659,43.5878,0.6026712,0,0,,0,O88307,Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),GO:0005794; GO:0008203; GO:0006897; GO:0005768; GO:0016021; GO:0006869; GO:0034362; GO:0030169; GO:0007275; GO:0048471,Golgi apparatus; cholesterol metabolic process; endocytosis; endosome; integral to membrane; lipid transport; low-density lipoprotein particle; low-density lipoprotein particle binding; multicellular organismal development; perinuclear region of cytoplasm,PF00041;PF00057;PF00058;PF15902;PF15901;,,,,,,,,,SORL_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910] comp143825_c0_seq5,2674,43.6425,0.61373793,4,0,,0,O88307,Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),GO:0005794; GO:0008203; GO:0006897; GO:0005768; GO:0016021; GO:0006869; GO:0034362; GO:0030169; GO:0007275; GO:0048471,Golgi apparatus; cholesterol metabolic process; endocytosis; endosome; integral to membrane; lipid transport; low-density lipoprotein particle; low-density lipoprotein particle binding; multicellular organismal development; perinuclear region of cytoplasm,PF00041;PF00057;PF00058;PF15902;PF15901;,1.00E-13,CHOYP_SORL.3.3,,,,,,,SORL_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910] comp143825_c0_seq6,1859,40.2367,0.61280637,2,0,,,,,,,,,4.00E-12,CHOYP_PHUM_PHUM470230.1.1,,,,,,,,, comp143825_c0_seq8,4813,41.7411,0.56044254,5,0,,2.00E-65,Q91ZX7,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0005887; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0048471; GO:0010875; GO:0006898; GO:0032956; GO:0032429,aorta morphogenesis; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; integral to plasma membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; perinuclear region of cytoplasm; positive regulation of cholesterol efflux; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,3.00E-12,CHOYP_LRP2.6.7,,,,,,,LRP1_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429] comp143825_c0_seq9,2218,42.2002,0.60935045,0,0,,9.00E-168,Q98930,Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment),Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment),GO:0008203; GO:0006897; GO:0016021; GO:0006869; GO:0034362,cholesterol metabolic process; endocytosis; integral to membrane; lipid transport; low-density lipoprotein particle,PF00041;PF00057;PF00058;PF15902;PF15901;,1.00E-13,CHOYP_SORL.3.3,,,,,,,SORL_CHICK,Gallus gallus (Chicken),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869] comp143826_c0_seq1,1438,38.8734,0.59233371,0,7,,2.00E-41,Q9QXW9,Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (mLAT2) (Solute carrier family 7 member 8),Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (mLAT2) (Solute carrier family 7 member 8),GO:0015179; GO:0005275; GO:0016323; GO:0005737; GO:0016021; GO:0015101; GO:0005886; GO:0019534,L-amino acid transmembrane transporter activity; amine transmembrane transporter activity; basolateral plasma membrane; cytoplasm; integral to membrane; organic cation transmembrane transporter activity; plasma membrane; toxin transporter activity,PF13520;,,,4.00E-34,ruditapes_c9495,,,,,LAT2_MOUSE,Mus musculus (Mouse),amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; neutral amino acid transport [GO:0015804] comp143826_c0_seq2,1945,39.7943,0.50838343,8,2,,3.00E-62,Q9WTR6,Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT),Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT),GO:0015171; GO:0016021; GO:0070527; GO:0009636,amino acid transmembrane transporter activity; integral to membrane; platelet aggregation; response to toxic substance,PF13520;,,,,,,,,,XCT_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; lens fiber cell differentiation [GO:0070306]; L-glutamate transmembrane transport [GO:0089711]; platelet aggregation [GO:0070527]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636] comp143826_c0_seq4,1819,39.967,0.53907512,0,7,,2.00E-40,Q9QXW9,Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (mLAT2) (Solute carrier family 7 member 8),Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (mLAT2) (Solute carrier family 7 member 8),GO:0015179; GO:0005275; GO:0016323; GO:0005737; GO:0016021; GO:0015101; GO:0005886; GO:0019534,L-amino acid transmembrane transporter activity; amine transmembrane transporter activity; basolateral plasma membrane; cytoplasm; integral to membrane; organic cation transmembrane transporter activity; plasma membrane; toxin transporter activity,PF13520;,,,,,,,,,LAT2_MOUSE,Mus musculus (Mouse),amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; neutral amino acid transport [GO:0015804] comp143827_c0_seq1,4442,43.1112,0.49067085,0,0,,6.00E-22,Q9BXF3,Cat eye syndrome critical region protein 2,Cat eye syndrome critical region protein 2,GO:0043044; GO:0090537; GO:0006309; GO:0090102; GO:0000910; GO:0007010; GO:0060122; GO:0001842; GO:0001843; GO:0005719; GO:0016192,ATP-dependent chromatin remodeling; CERF complex; apoptotic DNA fragmentation; cochlea development; cytokinesis; cytoskeleton organization; inner ear receptor stereocilium organization; neural fold formation; neural tube closure; nuclear euchromatin; vesicle-mediated transport,PF00439;,9.00E-12,CHOYP_CECR2.3.3,,,,,,,CECR2_HUMAN,Homo sapiens (Human),apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytokinesis [GO:0000910]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; neural tube development [GO:0021915]; vesicle-mediated transport [GO:0016192] comp143827_c0_seq3,4430,43.1377,0.49135066,10,105,,5.00E-22,Q9BXF3,Cat eye syndrome critical region protein 2,Cat eye syndrome critical region protein 2,GO:0043044; GO:0090537; GO:0006309; GO:0090102; GO:0000910; GO:0007010; GO:0060122; GO:0001842; GO:0001843; GO:0005719; GO:0016192,ATP-dependent chromatin remodeling; CERF complex; apoptotic DNA fragmentation; cochlea development; cytokinesis; cytoskeleton organization; inner ear receptor stereocilium organization; neural fold formation; neural tube closure; nuclear euchromatin; vesicle-mediated transport,PF00439;,9.00E-12,CHOYP_CECR2.3.3,,,,,,,CECR2_HUMAN,Homo sapiens (Human),apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytokinesis [GO:0000910]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; neural tube development [GO:0021915]; vesicle-mediated transport [GO:0016192] comp143827_c1_seq1,1461,42.642,0.63056681,365,4074,,1.00E-54,Q9BXF3,Cat eye syndrome critical region protein 2,Cat eye syndrome critical region protein 2,GO:0043044; GO:0090537; GO:0006309; GO:0090102; GO:0000910; GO:0007010; GO:0060122; GO:0001842; GO:0001843; GO:0005719; GO:0016192,ATP-dependent chromatin remodeling; CERF complex; apoptotic DNA fragmentation; cochlea development; cytokinesis; cytoskeleton organization; inner ear receptor stereocilium organization; neural fold formation; neural tube closure; nuclear euchromatin; vesicle-mediated transport,PF00439;,2.00E-13,CHOYP_CECR2.3.3,,,,,,,CECR2_HUMAN,Homo sapiens (Human),apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytokinesis [GO:0000910]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; neural tube development [GO:0021915]; vesicle-mediated transport [GO:0016192] comp143829_c2_seq11,1172,43.5154,0.25273966,0,0,,5.00E-24,P49025,"Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)","Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)",GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0035556; GO:0046872; GO:0007091; GO:0000070; GO:0050774; GO:0045665; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; negative regulation of neuron differentiation; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,,,,,,,,,CTRO_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283] comp143829_c2_seq18,1203,43.4746,0.29940631,0,0,,6.00E-24,P49025,"Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)","Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)",GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0035556; GO:0046872; GO:0007091; GO:0000070; GO:0050774; GO:0045665; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; negative regulation of neuron differentiation; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,,,,,,,,,CTRO_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283] comp143829_c2_seq25,2003,38.7918,0.23994897,0,0,,6.00E-23,P49025,"Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)","Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)",GO:0005524; GO:0015629; GO:0000910; GO:0016358; GO:0035556; GO:0046872; GO:0007091; GO:0000070; GO:0050774; GO:0045665; GO:0005543; GO:0004674; GO:0001726; GO:0005083; GO:0007283; GO:0005773,ATP binding; actin cytoskeleton; cytokinesis; dendrite development; intracellular signal transduction; metal ion binding; metaphase/anaphase transition of mitotic cell cycle; mitotic sister chromatid segregation; negative regulation of dendrite morphogenesis; negative regulation of neuron differentiation; phospholipid binding; protein serine/threonine kinase activity; ruffle; small GTPase regulator activity; spermatogenesis; vacuole,PF00780;PF00169;PF00069;,,,,,,,,,CTRO_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283] comp143830_c1_seq4,1454,44.0165,0.3662529,0,0,,3.00E-54,Q96NL6,Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1),Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1),GO:0005814; GO:0042384; GO:0071439; GO:0045162; GO:0045111; GO:0017080,centriole; cilium assembly; clathrin complex; clustering of voltage-gated sodium channels; intermediate filament cytoskeleton; sodium channel regulator activity,,3.00E-57,CHOYP_LOC591283.1.1,,,,,,,SCLT1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; clustering of voltage-gated sodium channels [GO:0045162] comp143830_c1_seq8,967,41.5719,0.47925838,0,10,,1.00E-13,Q96NL6,Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1),Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1),GO:0005814; GO:0042384; GO:0071439; GO:0045162; GO:0045111; GO:0017080,centriole; cilium assembly; clathrin complex; clustering of voltage-gated sodium channels; intermediate filament cytoskeleton; sodium channel regulator activity,,7.00E-31,CHOYP_SCLT1.1.1,,,,,,,SCLT1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; clustering of voltage-gated sodium channels [GO:0045162] comp143831_c0_seq1,2795,38.1395,0.42696276,480,297,,1.00E-28,Q9PTG8,Transforming acidic coiled-coil-containing protein 3 (Cytoplasmic polyadenylation element-binding protein-associated factor Maskin) (CPEB-associated factor Maskin),Transforming acidic coiled-coil-containing protein 3 (Cytoplasmic polyadenylation element-binding protein-associated factor Maskin) (CPEB-associated factor Maskin),GO:0005737; GO:0017148; GO:0043234,cytoplasm; negative regulation of translation; protein complex,PF05010;,,,,,,,,,TACC3_XENLA,Xenopus laevis (African clawed frog),negative regulation of translation [GO:0017148] comp143831_c0_seq2,1231,39.3176,0.43445325,41,14,,1.00E-24,O75410,Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1),Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1),GO:0007049; GO:0051301; GO:0021987; GO:0005737; GO:0022027; GO:0045111; GO:0015630; GO:0000226; GO:0005815; GO:0022008; GO:0005634; GO:0032886,cell cycle; cell division; cerebral cortex development; cytoplasm; interkinetic nuclear migration; intermediate filament cytoskeleton; microtubule cytoskeleton; microtubule cytoskeleton organization; microtubule organizing center; neurogenesis; nucleus; regulation of microtubule-based process,PF05010;,,,,,,,,,TACC1_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; microtubule cytoskeleton organization [GO:0000226] comp143832_c0_seq1,3255,42.4578,0.42961897,0,0,,3.00E-48,A2RRV3,Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b),Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b),GO:0016605; GO:0003723; GO:0000932; GO:0033962; GO:0000290; GO:0016607,PML body; RNA binding; cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; deadenylation-dependent decapping of nuclear-transcribed mRNA; nuclear speck,PF09770;,,,,,,,,,PATL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290] comp143832_c0_seq2,3396,42.9034,0.42888993,0,0,,7.00E-48,A2RRV3,Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b),Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b),GO:0016605; GO:0003723; GO:0000932; GO:0033962; GO:0000290; GO:0016607,PML body; RNA binding; cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; deadenylation-dependent decapping of nuclear-transcribed mRNA; nuclear speck,PF09770;,3.00E-17,CHOYP_BRAFLDRAFT_119484.3.3,,,,,,,PATL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290] comp143832_c0_seq4,2337,46.2559,0.37614937,0,0,,6.00E-07,O42958,DNA topoisomerase 2-associated protein pat1 (Decapping activator and translational repressor pat1) (Topoisomerase II-associated protein pat1),DNA topoisomerase 2-associated protein pat1 (Decapping activator and translational repressor pat1) (Topoisomerase II-associated protein pat1),GO:0003723; GO:0007049; GO:0051301; GO:0000932; GO:0002183; GO:0005829; GO:0000290; GO:0006397; GO:0006446,RNA binding; cell cycle; cell division; cytoplasmic mRNA processing body; cytoplasmic translational initiation; cytosol; deadenylation-dependent decapping of nuclear-transcribed mRNA; mRNA processing; regulation of translational initiation,PF09770;,,,,,,,,,PAT1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; regulation of translation [GO:0006417] comp143833_c0_seq1,5608,34.0228,0.36253758,1802,13265,,2.00E-57,P07602,Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)],Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)],GO:0005794; GO:0071310; GO:0008047; GO:0060742; GO:0005615; GO:0006687; GO:0016021; GO:0008289; GO:0006869; GO:0043202; GO:0005765; GO:0005739; GO:0030168; GO:0002576; GO:0060736; GO:0043408; GO:0019216; GO:0044281,Golgi apparatus; cellular response to organic substance; enzyme activator activity; epithelial cell differentiation involved in prostate gland development; extracellular space; glycosphingolipid metabolic process; integral to membrane; lipid binding; lipid transport; lysosomal lumen; lysosomal membrane; mitochondrion; platelet activation; platelet degranulation; prostate gland growth; regulation of MAPK cascade; regulation of lipid metabolic process; small molecule metabolic process,PF02199;PF05184;PF03489;,,,,,,,,,SAP_HUMAN,Homo sapiens (Human),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; platelet degranulation [GO:0002576]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216] comp143834_c0_seq3,1087,41.4903,0.42903936,2,0,,,,,,,,,1.00E-52,CHOYP_IPO9.4.4,,,,,,,,, comp143834_c0_seq5,3732,43.0064,0.49114116,54,77,,0,Q91YE6,Importin-9 (Imp9) (Importin-9a) (Imp9a) (Importin-9b) (Imp9b) (Ran-binding protein 9) (RanBP9),Importin-9 (Imp9) (Importin-9a) (Imp9a) (Importin-9b) (Imp9b) (Ran-binding protein 9) (RanBP9),GO:0008536; GO:0005737; GO:0042393; GO:0005634; GO:0050821; GO:0008565; GO:0006610; GO:0042254,Ran GTPase binding; cytoplasm; histone binding; nucleus; protein stabilization; protein transporter activity; ribosomal protein import into nucleus; ribosome biogenesis,PF03810;,0,CHOYP_IPO9.1.4,,,,,,,IPO9_MOUSE,Mus musculus (Mouse),protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; ribosomal protein import into nucleus [GO:0006610]; ribosome biogenesis [GO:0042254]; transcription factor import into nucleus [GO:0042991] comp143834_c0_seq6,2191,45.3674,0.5028904,0,0,,1.00E-12,P53067,Importin subunit beta-5 (114 kDa karyopherin) (Karyopherin subunit beta-5) (Karyopherin-114),Importin subunit beta-5 (114 kDa karyopherin) (Karyopherin subunit beta-5) (Karyopherin-114),GO:0005737; GO:0051028; GO:0005643; GO:0005634; GO:0008565; GO:0042991,cytoplasm; mRNA transport; nuclear pore; nucleus; protein transporter activity; transcription factor import into nucleus,PF03810;,,,9.00E-44,ruditapes_c18133,,,,,IMB5_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]; transcription factor import into nucleus [GO:0042991] comp143835_c0_seq1,2983,43.2786,0.48512796,22,19,,7.00E-44,Q9BXU1,Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine-protein kinase NYD-SPK) (Sugen kinase 396) (SgK396),Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine-protein kinase NYD-SPK) (Sugen kinase 396) (SgK396),GO:0005524; GO:0016788; GO:0003676; GO:0004674,"ATP binding; hydrolase activity, acting on ester bonds; nucleic acid binding; protein serine/threonine kinase activity",PF00069;PF00567;,,,,,,,,,STK31_HUMAN,Homo sapiens (Human), comp143835_c0_seq3,1314,43.7595,0.437394,5,3,,5.00E-08,Q58EK5,Tudor domain-containing protein 1,Tudor domain-containing protein 1,GO:0043046; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp143837_c0_seq1,1498,47.5968,0.55514169,0,0,,2.00E-31,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,3.00E-13,CHOYP_TITIN.10.19,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp143837_c0_seq11,718,46.2396,0.55245067,0,0,,,,,,,,,1.00E-13,CHOYP_PEVK.2.3,,,,,,,,, comp143837_c0_seq13,3144,48.0916,0.60619076,0,0,,1.00E-67,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp143837_c0_seq15,2716,48.0118,0.56333709,0,0,,5.00E-27,Q5VST9,Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK),GO:0005524; GO:0031430; GO:0005089; GO:0030018; GO:0097190; GO:0005829; GO:0046872; GO:0007275; GO:0048011; GO:0018108; GO:0005543; GO:0043065; GO:0036309; GO:0004674; GO:0004713; GO:0035023; GO:0051056; GO:0045214; GO:0007264; GO:0008307,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; Z disc; apoptotic signaling pathway; cytosol; metal ion binding; multicellular organismal development; neurotrophin TRK receptor signaling pathway; peptidyl-tyrosine phosphorylation; phospholipid binding; positive regulation of apoptotic process; protein localization to M-band; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; sarcomere organization; small GTPase mediated signal transduction; structural constituent of muscle,PF00041;PF07679;PF00612;PF00069;PF00621;,5.00E-13,CHOYP_TITIN.10.19,,,,,,,OBSCN_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214] comp143837_c0_seq16,3444,46.1382,0.66099779,0,0,,3.00E-40,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,2.00E-12,CHOYP_TITIN.19.19,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp143837_c0_seq2,4547,42.6655,0.68229004,9,41,,4.00E-56,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,,,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp143837_c0_seq3,2743,48.159,0.56714012,0,0,,1.00E-10,O95428,Papilin,Papilin,GO:0005604; GO:0004222; GO:0004867; GO:0008270,basement membrane; metalloendopeptidase activity; serine-type endopeptidase inhibitor activity; zinc ion binding,PF05986;PF07679;PF00014;PF08686;PF00090;,2.00E-12,CHOYP_TITIN.19.19,,,,,,,PPN_HUMAN,Homo sapiens (Human), comp143837_c0_seq4,1145,47.0742,0.68135111,0,0,,9.00E-17,Q64605,Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma),Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma),GO:0007155; GO:0016021; GO:0004725,cell adhesion; integral to membrane; protein tyrosine phosphatase activity,PF00041;PF07679;PF00102;,,,,,,,,,PTPRS_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp143837_c0_seq5,3171,48.2182,0.6088835,0,0,,2.00E-60,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,8.00E-11,CHOYP_PEVK.3.3,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp143837_c0_seq6,549,46.4481,0.54274264,0,0,,,,,,,,,9.00E-14,CHOYP_TITIN.10.19,,,,,,,,, comp143837_c0_seq8,4574,42.7853,0.68414116,0,0,,8.00E-44,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp143837_c0_seq9,3417,46.0053,0.65889216,0,0,,7.00E-39,Q9I7U4,Titin (D-Titin) (Kettin),Titin (D-Titin) (Kettin),GO:0030018; GO:0003779; GO:0051301; GO:0000794; GO:0040011; GO:0007498; GO:0005875; GO:0007076; GO:0016203; GO:0007520; GO:0035206; GO:0045214; GO:0007062; GO:0007519; GO:0007525; GO:0008307; GO:0007522,Z disc; actin binding; cell division; condensed nuclear chromosome; locomotion; mesoderm development; microtubule associated complex; mitotic chromosome condensation; muscle attachment; myoblast fusion; regulation of hemocyte proliferation; sarcomere organization; sister chromatid cohesion; skeletal muscle tissue development; somatic muscle development; structural constituent of muscle; visceral muscle development,PF06582;PF00041;PF07679;PF00018;,,,,,,,,,TITIN_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522] comp143837_c1_seq1,1631,41.6309,0.93621939,135,0,,2.00E-44,Q92959,Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2),Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2),GO:0005887; GO:0005319; GO:0015132; GO:0043252; GO:0055085,integral to plasma membrane; lipid transporter activity; prostaglandin transmembrane transporter activity; sodium-independent organic anion transport; transmembrane transport,PF07648;PF03137;,,,,,,,,,SO2A1_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869]; sodium-independent organic anion transport [GO:0043252] comp143839_c1_seq2,2275,40.7033,0.49103957,1132,5735,,0,Q5BJQ6,Cleavage stimulation factor subunit 1 (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50),Cleavage stimulation factor subunit 1 (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50),GO:0006397; GO:0005634,mRNA processing; nucleus,PF16699;PF00400;,0,CHOYP_LOC100367837.1.1,,,,,,,CSTF1_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397] comp143840_c0_seq1,4383,44.4216,0.57062161,105,113,,4.00E-74,Q640L5,Coiled-coil domain-containing protein 18,Coiled-coil domain-containing protein 18,,,,7.00E-51,CHOYP_LOC100372626.1.2,,,,,,,CCD18_MOUSE,Mus musculus (Mouse), comp143840_c0_seq3,4056,44.4527,0.58107731,40,29,,2.00E-66,Q640L5,Coiled-coil domain-containing protein 18,Coiled-coil domain-containing protein 18,,,,2.00E-25,CHOYP_LOC100372626.2.2,,,,,,,CCD18_MOUSE,Mus musculus (Mouse), comp143841_c0_seq1,3488,45.2122,0.4103191,156,24,,,,,,,,,0,CHOYP_LOC100368636.1.1,,,,,,,,, comp143841_c0_seq2,2591,45.0405,0.42035744,50,10,,4.00E-75,Q9C0B2,Uncharacterized protein KIAA1751,Cilia- and flagella-associated protein 74,,,,,,,,,,,,K1751_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082] comp143841_c0_seq3,415,44.3373,0.30000174,0,6,,2.00E-06,Q9C0B2,Uncharacterized protein KIAA1751,Cilia- and flagella-associated protein 74,,,,,,,,,,,,K1751_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082] comp143842_c1_seq14,2498,35.0681,0.53879575,0,0,,0,P32234,GTP-binding protein 128up,GTP-binding protein 128up,GO:0005525,GTP binding,PF01926;PF16897;PF02824;,0,CHOYP_DRG1.1.1,,,,,,,128UP_DROME,Drosophila melanogaster (Fruit fly), comp143842_c1_seq9,2510,35.0996,0.53508844,0,7,,0,P32234,GTP-binding protein 128up,GTP-binding protein 128up,GO:0005525,GTP binding,PF01926;PF16897;PF02824;,0,CHOYP_DRG1.1.1,,,,,,,128UP_DROME,Drosophila melanogaster (Fruit fly), comp143844_c2_seq3,1551,38.2334,0.65455402,0,45,,6.00E-79,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,2.00E-14,CHOYP_LOC100369190.1.1,1.00E-28,ruditapes_c10990,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp143846_c0_seq1,1106,41.7722,0.51898777,156,829,,9.00E-25,Q6P9B9,Integrator complex subunit 5 (Int5),Integrator complex subunit 5 (Int5),GO:0016021; GO:0032039; GO:0016180,integral to membrane; integrator complex; snRNA processing,PF14838;PF14837;,3.00E-24,CHOYP_BRAFLDRAFT_124611.1.1,,,,,,,INT5_HUMAN,Homo sapiens (Human),snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp143847_c0_seq1,806,45.0372,0.32023859,20,128,,2.00E-10,C1EMR8,"Phosphoadenosine phosphosulfate reductase (EC 1.8.4.8) (3'-phosphoadenylylsulfate reductase) (PAPS reductase, thioredoxin dependent) (PAPS sulfotransferase) (PAdoPS reductase)","Phosphoadenosine phosphosulfate reductase (EC 1.8.4.8) (3'-phosphoadenylylsulfate reductase) (PAPS reductase, thioredoxin dependent) (PAPS sulfotransferase) (PAdoPS reductase)",GO:0019344; GO:0005737; GO:0070814; GO:0004604; GO:0019379,"cysteine biosynthetic process; cytoplasm; hydrogen sulfide biosynthetic process; phosphoadenylyl-sulfate reductase (thioredoxin) activity; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)",PF01507;,,,,,,,,,CYSH_BACC3,Bacillus cereus (strain 03BB102),"cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]" comp143847_c0_seq2,1605,42.3676,0.44503347,68,549,,9.00E-178,Q6ING7,FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region],FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region],GO:0005524; GO:0006747; GO:0003919; GO:0006777,ATP binding; FAD biosynthetic process; FMN adenylyltransferase activity; Mo-molybdopterin cofactor biosynthetic process,PF00994;PF01507;,8.00E-90,CHOYP_LOC593348.1.1,,,,,,,FLAD1_XENLA,Xenopus laevis (African clawed frog),FAD biosynthetic process [GO:0006747] comp143847_c0_seq3,596,45.4698,0.32676611,7,26,,8.00E-43,O74841,Probable FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase),Probable FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase),GO:0005524; GO:0006747; GO:0003919; GO:0046444; GO:0005829; GO:0005634,ATP binding; FAD biosynthetic process; FMN adenylyltransferase activity; FMN metabolic process; cytosol; nucleus,PF01507;,,,,,,,,,FAD1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),FAD biosynthetic process [GO:0006747]; FMN metabolic process [GO:0046444] comp143850_c0_seq1,3917,39.4179,0.37484141,0,0,,0,P48377,MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1),MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX1_MOUSE,Mus musculus (Mouse),"immune response [GO:0006955]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq11,3796,39.0411,0.36677234,0,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,0,CHOYP_RFX3.1.1,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq12,4157,39.4996,0.33962266,0,0,,0,A0JMF8,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq13,3812,39.0346,0.36537849,0,0,,0,P48380,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0003705; GO:0048469; GO:0060285; GO:0042384; GO:0031018; GO:0060287; GO:0045892; GO:0000790; GO:0045944; GO:2000078; GO:0050796; GO:0005667; GO:0044212; GO:0072560,"RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; cell maturation; ciliary cell motility; cilium assembly; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; negative regulation of transcription, DNA-dependent; nuclear chromatin; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type B pancreatic cell development; regulation of insulin secretion; transcription factor complex; transcription regulatory region DNA binding; type B pancreatic cell maturation",PF04589;PF02257;,0,CHOYP_RFX3.1.1,,,,,,,RFX3_HUMAN,Homo sapiens (Human),"cell maturation [GO:0048469]; cilium assembly [GO:0042384]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell maturation [GO:0072560]" comp143850_c0_seq14,4114,39.7667,0.36305713,0,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq15,3695,38.8904,0.34405268,0,0,,0,P48377,MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1),MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04589;PF02257;,0,CHOYP_RFX3.1.1,,,,,,,RFX1_MOUSE,Mus musculus (Mouse),"immune response [GO:0006955]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq17,3876,39.3189,0.354266,2,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq19,3765,39.0969,0.3549108,10,0,,0,P48377,MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1),MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX1_MOUSE,Mus musculus (Mouse),"immune response [GO:0006955]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq2,3517,37.9016,0.33327021,0,0,,2.00E-72,Q33E94,Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10),Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10),GO:0003677; GO:0021696; GO:0003682; GO:0021516; GO:0030900; GO:0030901; GO:0005634; GO:0045944; GO:0006351,"DNA binding; cerebellar cortex morphogenesis; chromatin binding; dorsal spinal cord development; forebrain development; midbrain development; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF02257;,0,CHOYP_RFX3.1.1,,,,,,,RFX4_HUMAN,Homo sapiens (Human),cerebellar cortex morphogenesis [GO:0021696]; cilium assembly [GO:0042384]; dorsal spinal cord development [GO:0021516]; midbrain development [GO:0030901]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein processing [GO:0070613]; telencephalon development [GO:0021537] comp143850_c0_seq21,3260,38.1288,0.33826751,0,0,,1.00E-65,Q09555,RFX-like transcription factor daf-19 (Abnormal dauer formation protein 19),RFX-like transcription factor daf-19 (Abnormal dauer formation protein 19),GO:0003677; GO:0005634; GO:0006357; GO:0006351,"DNA binding; nucleus; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF02257;,0,CHOYP_RFX3.1.1,,,,,,,DAF19_CAEEL,Caenorhabditis elegans,"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq22,3934,39.4001,0.37357597,0,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq23,3501,37.9035,0.33472307,0,0,,2.00E-72,Q33E94,Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10),Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10),GO:0003677; GO:0021696; GO:0003682; GO:0021516; GO:0030900; GO:0030901; GO:0005634; GO:0045944; GO:0006351,"DNA binding; cerebellar cortex morphogenesis; chromatin binding; dorsal spinal cord development; forebrain development; midbrain development; nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF02257;,,,,,2.00E-131,CU995306.p.cg.6,7,,RFX4_HUMAN,Homo sapiens (Human),cerebellar cortex morphogenesis [GO:0021696]; cilium assembly [GO:0042384]; dorsal spinal cord development [GO:0021516]; midbrain development [GO:0030901]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein processing [GO:0070613]; telencephalon development [GO:0021537] comp143850_c0_seq3,4001,39.6401,0.36295683,0,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq4,3758,39.0101,0.32926982,0,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,0,CHOYP_RFX3.1.1,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143850_c0_seq5,4074,39.2734,0.35043681,0,0,,0,P48380,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0003705; GO:0048469; GO:0060285; GO:0042384; GO:0031018; GO:0060287; GO:0045892; GO:0000790; GO:0045944; GO:2000078; GO:0050796; GO:0005667; GO:0044212; GO:0072560,"RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; cell maturation; ciliary cell motility; cilium assembly; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; negative regulation of transcription, DNA-dependent; nuclear chromatin; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type B pancreatic cell development; regulation of insulin secretion; transcription factor complex; transcription regulatory region DNA binding; type B pancreatic cell maturation",PF04589;PF02257;,,,,,,,,,RFX3_HUMAN,Homo sapiens (Human),"cell maturation [GO:0048469]; cilium assembly [GO:0042384]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell maturation [GO:0072560]" comp143850_c0_seq6,3762,39.1547,0.33348845,0,0,,,,,,,,,0,CHOYP_RFX3.1.1,,,,,,,,, comp143850_c0_seq8,4031,39.5435,0.37463623,0,0,,0,Q0V9K5,Transcription factor RFX3 (Regulatory factor X 3),Transcription factor RFX3 (Regulatory factor X 3),GO:0030154; GO:0060285; GO:0031018; GO:0060287; GO:0005634; GO:0050796; GO:0006355; GO:0044212; GO:0006351,"cell differentiation; ciliary cell motility; endocrine pancreas development; epithelial cilium movement involved in determination of left/right asymmetry; nucleus; regulation of insulin secretion; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF04589;PF02257;,,,,,,,,,RFX3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp143851_c1_seq1,1989,30.719,1.13379372,11,30,,4.00E-09,Q03270,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO12_NASVI,Nasonia vitripennis (Parasitic wasp), comp143851_c1_seq2,1929,30.7413,1.07735276,13,106,,8.00E-36,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,3.00E-33,CHOYP_LOC100892567.1.8,8.00E-25,ruditapes_c16815,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp143852_c0_seq1,2140,35.9813,0.48063276,0,11,,4.00E-16,Q6DFJ3,FUN14 domain-containing protein 1B,FUN14 domain-containing protein 1B,GO:0031307; GO:0000422; GO:0001666,integral to mitochondrial outer membrane; mitochondrion degradation; response to hypoxia,PF04930;,,,,,,,,,FUD1B_XENLA,Xenopus laevis (African clawed frog),mitophagy [GO:0000422]; response to hypoxia [GO:0001666] comp143852_c0_seq10,2119,36.0076,0.48537503,0,2,,4.00E-16,Q6DFJ3,FUN14 domain-containing protein 1B,FUN14 domain-containing protein 1B,GO:0031307; GO:0000422; GO:0001666,integral to mitochondrial outer membrane; mitochondrion degradation; response to hypoxia,PF04930;,,,,,,,,,FUD1B_XENLA,Xenopus laevis (African clawed frog),mitophagy [GO:0000422]; response to hypoxia [GO:0001666] comp143852_c0_seq2,2157,35.8832,0.49286296,1,79,,1.00E-15,Q58EA0,FUN14 domain-containing protein 1A,FUN14 domain-containing protein 1A,GO:0031307; GO:0000422; GO:0001666,integral to mitochondrial outer membrane; mitochondrion degradation; response to hypoxia,PF04930;,,,,,,,,,FUD1A_XENLA,Xenopus laevis (African clawed frog),mitophagy [GO:0000422]; response to hypoxia [GO:0001666] comp143852_c0_seq7,1459,37.0802,0.44805288,0,0,,2.00E-16,Q6DFJ3,FUN14 domain-containing protein 1B,FUN14 domain-containing protein 1B,GO:0031307; GO:0000422; GO:0001666,integral to mitochondrial outer membrane; mitochondrion degradation; response to hypoxia,PF04930;,,,,,,,,,FUD1B_XENLA,Xenopus laevis (African clawed frog),mitophagy [GO:0000422]; response to hypoxia [GO:0001666] comp143852_c0_seq8,1392,37.2845,0.44418317,0,0,,1.00E-11,Q9D6K8,FUN14 domain-containing protein 2 (Hepatitis C virus core-binding protein 6),FUN14 domain-containing protein 2 (Hepatitis C virus core-binding protein 6),GO:0005739,mitochondrion,PF04930;,,,,,,,,,FUND2_MOUSE,Mus musculus (Mouse),mitophagy [GO:0000422] comp143854_c1_seq1,207,39.1304,0.88890963,3,13,,,,,,,,,,,4.00E-29,ruditapes_c13125,,,,,,, comp143855_c0_seq2,3429,40.4491,0.4183455,1109,904,,0,Q6VH22,Intraflagellar transport protein 172 homolog (Protein wimple),Intraflagellar transport protein 172 homolog (Protein wimple),GO:0042384; GO:0007368; GO:0009953; GO:0030990; GO:0005932; GO:0001841; GO:0016485; GO:0007224; GO:0097225; GO:0097228; GO:0021522,cilium assembly; determination of left/right symmetry; dorsal/ventral pattern formation; intraflagellar transport particle; microtubule basal body; neural tube formation; protein processing; smoothened signaling pathway; sperm midpiece; sperm principal piece; spinal cord motor neuron differentiation,PF00400;,,,,,,,,,IF172_MOUSE,Mus musculus (Mouse),bone development [GO:0060348]; brain development [GO:0007420]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; hindgut development [GO:0061525]; left/right axis specification [GO:0070986]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; palate development [GO:0060021]; positive regulation of smoothened signaling pathway [GO:0045880]; protein processing [GO:0016485]; regulation of smoothened signaling pathway [GO:0008589]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522] comp143855_c0_seq5,2050,44.2439,0.44596662,34,3,,0,Q9W040,Intraflagellar transport protein osm-1 (Osmotic avoidance abnormal protein 1 homolog),Intraflagellar transport protein 172 homolog (Osmotic avoidance abnormal protein 1 homolog) (Outer segment 2),GO:0005871; GO:0007018; GO:0007275; GO:0031513; GO:0035058,kinesin complex; microtubule-based movement; multicellular organismal development; nonmotile primary cilium; nonmotile primary cilium assembly,,0,CHOYP_LOC100376289.1.1,,,,,,,OSM1_DROME,Drosophila melanogaster (Fruit fly),cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]; nonmotile primary cilium assembly [GO:0035058] comp143856_c2_seq1,1052,42.3004,0.55571844,67,103,,2.00E-82,Q8NCC3,Group XV phospholipase A2 (EC 2.3.1.-) (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (Lysophospholipase 3) (Lysosomal phospholipase A2) (LPLA2),Group XV phospholipase A2 (EC 2.3.1.-) (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (Lysophospholipase 3) (Lysosomal phospholipase A2) (LPLA2),GO:0008374; GO:0047499; GO:0006672; GO:0005576; GO:0009062; GO:0004622; GO:0005764; GO:0005739; GO:0046470; GO:0005543,O-acyltransferase activity; calcium-independent phospholipase A2 activity; ceramide metabolic process; extracellular region; fatty acid catabolic process; lysophospholipase activity; lysosome; mitochondrion; phosphatidylcholine metabolic process; phospholipid binding,PF02450;,6.00E-45,CHOYP_BRAFLDRAFT_230181.1.1,,,,,,,PAG15_HUMAN,Homo sapiens (Human),ceramide metabolic process [GO:0006672]; fatty acid catabolic process [GO:0009062]; glycerophospholipid metabolic process [GO:0006650]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338] comp143856_c4_seq1,2081,42.9601,0.46901506,378,583,,0,P0AC33,"Fumarate hydratase class I, aerobic (Fumarase) (EC 4.2.1.2)","Fumarate hydratase class I, aerobic (EC 4.2.1.2) (Fumarase A) (Oxaloacetate keto--enol-isomerase) (OAAKE isomerase) (Oxaloacetate tautomerase) (EC 5.3.2.2)",GO:0051539; GO:0005829; GO:0004333; GO:0046872; GO:0050163; GO:0006099,"4 iron, 4 sulfur cluster binding; cytosol; fumarate hydratase activity; metal ion binding; oxaloacetate tautomerase activity; tricarboxylic acid cycle",PF05681;PF05683;,0,CHOYP_CHD5.2.2,1.00E-55,ruditapes_c9015,,,,,FUMA_ECOLI,Escherichia coli (strain K12),tricarboxylic acid cycle [GO:0006099] comp143858_c0_seq4,5263,41.7253,0.45987839,649,1469,,4.00E-22,P52746,Zinc finger protein 142 (HA4654),Zinc finger protein 142 (HA4654),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,1.00E-49,CHOYP_ZSCA2.1.2,,,,,,,ZN142_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143859_c2_seq2,3881,44.5246,0.63363608,60,0,,4.00E-109,Q6UJY2,Sodium/hydrogen exchanger 10 (Na(+)/H(+) exchanger 10) (NHE-10) (Solute carrier family 10 member 10) (Solute carrier family 9 member C1) (Sperm-specific Na(+)/H(+) exchanger) (sNHE),Sodium/hydrogen exchanger 10 (Na(+)/H(+) exchanger 10) (NHE-10) (Solute carrier family 10 member 10) (Solute carrier family 9 member C1) (Sperm-specific Na(+)/H(+) exchanger) (sNHE),GO:0030154; GO:0060170; GO:0016021; GO:0007275; GO:0006814; GO:0015299; GO:0030317; GO:0007283,cell differentiation; cilium membrane; integral to membrane; multicellular organismal development; sodium ion transport; solute:hydrogen antiporter activity; sperm motility; spermatogenesis,PF00027;PF00999;,,,,,,,,,SL9C1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; ion transmembrane transport [GO:0034220]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp143859_c2_seq3,3785,44.2008,0.61615951,42,0,,1.00E-14,Q8RWU6,Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6),Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6),GO:0032580; GO:0005768; GO:0010008; GO:0016021; GO:0006885; GO:0015385,Golgi cisterna membrane; endosome; endosome membrane; integral to membrane; regulation of pH; sodium:hydrogen antiporter activity,PF00999;,0,CHOYP_LOC100371138.1.1,,,,,,,NHX6_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of pH [GO:0006885] comp143860_c0_seq2,820,40.122,0.76159668,28,121,,3.00E-55,Q9H0Z9,RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4),RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4),GO:0070935; GO:0006977; GO:0006978; GO:0008380; GO:0007049; GO:0007050; GO:0030154; GO:0005829; GO:0003730; GO:0003729; GO:0006397; GO:0008285; GO:0000166; GO:0005634; GO:0043484; GO:0010830,"3'-UTR-mediated mRNA stabilization; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; RNA splicing; cell cycle; cell cycle arrest; cell differentiation; cytosol; mRNA 3'-UTR binding; mRNA binding; mRNA processing; negative regulation of cell proliferation; nucleotide binding; nucleus; regulation of RNA splicing; regulation of myotube differentiation",PF00076;,1.00E-64,CHOYP_RB24A.1.1,,,,,,,RBM38_HUMAN,Homo sapiens (Human),"3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; negative regulation of cell proliferation [GO:0008285]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]" comp143861_c0_seq1,3848,39.527,0.67958364,56,151,,0,O35345,Importin subunit alpha-7 (Importin alpha-S2) (Karyopherin subunit alpha-6),Importin subunit alpha-7 (Importin alpha-S2) (Karyopherin subunit alpha-6),GO:0005737; GO:0060135; GO:0005634; GO:0045944; GO:0006606; GO:0008565,cytoplasm; maternal process involved in female pregnancy; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein import into nucleus; protein transporter activity,PF00514;PF16186;PF01749;,0,CHOYP_BRAFLDRAFT_279360.1.1,,,,,,,IMA7_MOUSE,Mus musculus (Mouse),maternal process involved in female pregnancy [GO:0060135]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus [GO:0006606] comp143861_c0_seq3,3337,39.1669,0.6719766,37,104,,0,Q0V7M0,Importin subunit alpha-7 (Karyopherin subunit alpha-6),Importin subunit alpha-7 (Karyopherin subunit alpha-6),GO:0005737; GO:0005634; GO:0006606; GO:0008565,cytoplasm; nucleus; protein import into nucleus; protein transporter activity,PF00514;PF16186;PF01749;,,,3.00E-20,ruditapes_c13431,,,,,IMA7_BOVIN,Bos taurus (Bovine),NLS-bearing protein import into nucleus [GO:0006607] comp143862_c0_seq1,3581,36.1072,0.42231422,15,54,,8.00E-85,Q99JZ0,Syntenin-2 (Syndecan-binding protein 2),Syntenin-2 (Syndecan-binding protein 2),GO:0005737; GO:0008022; GO:0046982; GO:0042803,cytoplasm; protein C-terminus binding; protein heterodimerization activity; protein homodimerization activity,PF00595;,7.00E-82,CHOYP_SDCB1.1.1,,,,,,,SDCB2_MOUSE,Mus musculus (Mouse), comp143862_c0_seq2,3347,36.0621,0.39852512,0,0,,7.00E-104,O08992,Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1),Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1),GO:0007265; GO:0070062; GO:0005137; GO:0005895; GO:0042470; GO:0042327,Ras protein signal transduction; extracellular vesicular exosome; interleukin-5 receptor binding; interleukin-5 receptor complex; melanosome; positive regulation of phosphorylation,PF00595;,,,,,,,,,SDCB1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; Ras protein signal transduction [GO:0007265]; regulation of mitotic cell cycle [GO:0007346] comp143862_c0_seq4,3444,36.4692,0.41327728,0,0,,7.00E-85,Q99JZ0,Syntenin-2 (Syndecan-binding protein 2),Syntenin-2 (Syndecan-binding protein 2),GO:0005737; GO:0008022; GO:0046982; GO:0042803,cytoplasm; protein C-terminus binding; protein heterodimerization activity; protein homodimerization activity,PF00595;,3.00E-92,CHOYP_KDM1A.1.1,,,,,,,SDCB2_MOUSE,Mus musculus (Mouse), comp143862_c0_seq7,3484,35.6774,0.39983732,0,0,,1.00E-103,O08992,Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1),Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1),GO:0007265; GO:0070062; GO:0005137; GO:0005895; GO:0042470; GO:0042327,Ras protein signal transduction; extracellular vesicular exosome; interleukin-5 receptor binding; interleukin-5 receptor complex; melanosome; positive regulation of phosphorylation,PF00595;,3.00E-92,CHOYP_KDM1A.1.1,,,,,,,SDCB1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; Ras protein signal transduction [GO:0007265]; regulation of mitotic cell cycle [GO:0007346] comp143864_c0_seq10,3512,45.4727,0.47431835,0,5,,,,,,,,,0,CHOYP_LOC100368865.1.1,,,,,,,,, comp143864_c0_seq11,3397,45.8051,0.47205454,0,0,,0,Q86VS3,IQ domain-containing protein H (Testis development protein NYD-SP5),IQ domain-containing protein H (Testis development protein NYD-SP5),,,,0,CHOYP_LOC100368865.1.1,,,,,,,IQCH_HUMAN,Homo sapiens (Human), comp143864_c0_seq12,3488,45.6422,0.49064213,0,0,,0,Q9D2K4,IQ domain-containing protein H,IQ domain-containing protein H,,,,,,,,,,,,IQCH_MOUSE,Mus musculus (Mouse), comp143864_c0_seq13,2961,46.7072,0.45856195,0,0,,,,,,,,,1.00E-14,CHOYP_IQCH.1.1,,,,,,,,, comp143864_c0_seq16,3373,45.9828,0.48300296,0,0,,0,Q9D2K4,IQ domain-containing protein H,IQ domain-containing protein H,,,,0,CHOYP_LOC100368865.1.1,,,,,,,IQCH_MOUSE,Mus musculus (Mouse), comp143864_c0_seq2,2187,47.6909,0.42641671,0,0,,,,,,,,,9.00E-15,CHOYP_IQCH.1.1,,,,,,,,, comp143864_c0_seq4,3497,45.3532,0.47328664,0,0,,0,Q9D2K4,IQ domain-containing protein H,IQ domain-containing protein H,,,,0,CHOYP_LOC100368865.1.1,,,,,,,IQCH_MOUSE,Mus musculus (Mouse), comp143864_c0_seq5,3473,45.6378,0.49272359,0,0,,0,Q9D2K4,IQ domain-containing protein H,IQ domain-containing protein H,,,,,,,,,,,,IQCH_MOUSE,Mus musculus (Mouse), comp143864_c0_seq6,2211,47.3994,0.41087248,0,0,,,,,,,,,9.00E-15,CHOYP_IQCH.1.1,,,,,,,,, comp143864_c0_seq8,3076,46.3589,0.46621217,0,0,,,,,,,,,0,CHOYP_LOC100368865.1.1,,,,,,,,, comp143865_c0_seq1,949,43.098,0.57258973,2,0,,1.00E-14,P56094,General transcriptional corepressor TUP1,General transcriptional corepressor TUP1,GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP1_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),"histone exchange [GO:0043486]; negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter [GO:0035955]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; nucleosome positioning [GO:0016584]; regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter [GO:2000531]; regulation of invasive growth in response to glucose limitation [GO:2000217]; regulation of response to DNA damage stimulus [GO:2001020]; transcription, DNA-templated [GO:0006351]" comp143865_c0_seq2,3330,39.9099,0.54392813,360,15,,8.00E-13,Q00808,Vegetative incompatibility protein HET-E-1,Vegetative incompatibility protein HET-E-1,GO:0005525,GTP binding,PF06985;PF00400;,0,CHOYP_BRAFLDRAFT_117940.1.1,1.00E-18,ruditapes_c12006,,,,,HETE1_PODAS,Podospora anserina (Pleurage anserina), comp143865_c0_seq3,1413,41.6844,0.48071039,46,19,,2.00E-14,P16649,General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2),General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2),GO:0001191; GO:0042393; GO:0042826; GO:0043486; GO:0036033; GO:0035955; GO:0001198; GO:0000433; GO:0007070; GO:0016584; GO:0080025; GO:2000531; GO:2001020; GO:0061418; GO:0061392; GO:0017053; GO:0043130,"RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; histone binding; histone deacetylase binding; histone exchange; mediator complex binding; negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; negative regulation of mating-type specific transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter by glucose; negative regulation of transcription from RNA polymerase II promoter during mitosis; nucleosome positioning; phosphatidylinositol-3,5-bisphosphate binding; regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; regulation of response to DNA damage stimulus; regulation of transcription from RNA polymerase II promoter in response to hypoxia; regulation of transcription from RNA polymerase II promoter in response to osmotic stress; transcriptional repressor complex; ubiquitin binding",PF08581;PF00400;,,,,,,,,,TUP1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"histone exchange [GO:0043486]; negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter [GO:0035955]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; nucleosome positioning [GO:0016584]; regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter [GO:2000531]; regulation of invasive growth in response to glucose limitation [GO:2000217]; regulation of response to DNA damage stimulus [GO:2001020]; transcription, DNA-templated [GO:0006351]" comp143866_c1_seq1,1031,38.3123,1.17680098,7,30,,1.00E-45,O42412,Type III iodothyronine deiodinase (EC 1.97.1.11) (5DIII) (DIOIII) (Type 3 DI) (Type-III 5'-deiodinase) (Fragment),Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) (Fragment),GO:0010008; GO:0042446; GO:0016021; GO:0005886; GO:0004800; GO:0033798,endosome membrane; hormone biosynthetic process; integral to membrane; plasma membrane; thyroxine 5'-deiodinase activity; thyroxine 5-deiodinase activity,PF00837;,,,,,,,,,IOD3_CHICK,Gallus gallus (Chicken),hormone biosynthetic process [GO:0042446] comp143866_c1_seq2,1669,40.8628,0.74988801,19,25,,2.00E-43,P49898,Type III iodothyronine deiodinase (EC 1.97.1.11) (5DIII) (DIOIII) (Type 3 DI) (Type-III 5'-deiodinase),Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase),GO:0010008; GO:0042446; GO:0016021; GO:0005886; GO:0004800; GO:0033798,endosome membrane; hormone biosynthetic process; integral to membrane; plasma membrane; thyroxine 5'-deiodinase activity; thyroxine 5-deiodinase activity,PF00837;,,,,,,,,,IOD3_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),hormone biosynthetic process [GO:0042446] comp143866_c1_seq3,1745,40.6877,0.82048899,26,10,,4.00E-39,Q804E1,Type I iodothyronine deiodinase (EC 1.97.1.10) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase),Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase),GO:0005789; GO:0042446; GO:0016021; GO:0004800,endoplasmic reticulum membrane; hormone biosynthetic process; integral to membrane; thyroxine 5'-deiodinase activity,PF00837;,,,,,,,,,IOD1_FUNHE,Fundulus heteroclitus (Killifish) (Mummichog),hormone biosynthetic process [GO:0042446] comp143866_c1_seq5,955,38.8482,1.06878611,0,0,,2.00E-44,P49898,Type III iodothyronine deiodinase (EC 1.97.1.11) (5DIII) (DIOIII) (Type 3 DI) (Type-III 5'-deiodinase),Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase),GO:0010008; GO:0042446; GO:0016021; GO:0005886; GO:0004800; GO:0033798,endosome membrane; hormone biosynthetic process; integral to membrane; plasma membrane; thyroxine 5'-deiodinase activity; thyroxine 5-deiodinase activity,PF00837;,,,,,,,,,IOD3_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),hormone biosynthetic process [GO:0042446] comp143867_c0_seq1,1176,41.7517,0.5680506,28,129,,1.00E-44,P12394,"Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.99.9) (EC 4.1.2.30) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17)","Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 4.1.2.30) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17)",GO:0047442; GO:0020037; GO:0042446; GO:0005506; GO:0016020; GO:0004508; GO:0006694; GO:0008202,17-alpha-hydroxyprogesterone aldolase activity; heme binding; hormone biosynthetic process; iron ion binding; membrane; steroid 17-alpha-monooxygenase activity; steroid biosynthetic process; steroid metabolic process,PF00067;,,,,,,,,,CP17A_CHICK,Gallus gallus (Chicken),hormone biosynthetic process [GO:0042446]; sex differentiation [GO:0007548]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] comp143867_c0_seq2,1331,39.5943,0.55880597,34,38,,9.00E-49,Q9CX98,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,3.00E-18,CHOYP_TBA.2.6,8.00E-17,ruditapes_c28705,,,,,CP2U1_MOUSE,Mus musculus (Mouse), comp143867_c0_seq3,1710,35.9064,0.71200408,119,482,,1.00E-32,O48956,Cytochrome P450 98A1 (EC 1.14.-.-),Cytochrome P450 98A1 (EC 1.14.-.-),GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705,"heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C98A1_SORBI,Sorghum bicolor (Sorghum) (Sorghum vulgare), comp143867_c0_seq4,1387,37.491,0.55648639,13,49,,1.00E-45,P51589,Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),GO:0008405; GO:0008404; GO:0070330; GO:0005789; GO:0019373; GO:0020037; GO:0005506; GO:0071614; GO:0043651; GO:0008016; GO:0006805,"arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; aromatase activity; endoplasmic reticulum membrane; epoxygenase P450 pathway; heme binding; iron ion binding; linoleic acid epoxygenase activity; linoleic acid metabolic process; regulation of heart contraction; xenobiotic metabolic process",PF00067;,3.00E-18,CHOYP_LOC100371830.3.6,,,,,,,CP2J2_HUMAN,Homo sapiens (Human),epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805] comp143867_c2_seq1,1094,40.2194,0.52311858,20,89,,4.00E-13,P37119,Cytochrome P450 71A3 (EC 1.14.-.-) (CYPLXXIA3) (Cytochrome P-450EG3) (Fragment),Cytochrome P450 71A3 (EC 1.14.-.-) (CYPLXXIA3) (Cytochrome P-450EG3) (Fragment),GO:0020037; GO:0005506; GO:0004497; GO:0016705,"heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,2.00E-18,ruditapes_c14798,,,,,C71A3_SOLME,Solanum melongena (Eggplant) (Aubergine), comp143867_c2_seq4,567,41.9753,0.4829947,8,49,,1.00E-22,O22203,Cytochrome P450 98A3 (EC 1.14.-.-) (Protein REDUCED EPIDERMAL FLUORESCENCE 8) (p-coumaroylshikimate/quinate 3'-hydrolxylase) (C3'H),Cytochrome P450 98A3 (EC 1.14.-.-) (Protein REDUCED EPIDERMAL FLUORESCENCE 8) (p-coumaroylshikimate/quinate 3'-hydrolxylase) (C3'H),GO:0009805; GO:0005783; GO:0009813; GO:0020037; GO:0016021; GO:0005506; GO:0009809; GO:0005739; GO:0016705; GO:0046409; GO:0005886,"coumarin biosynthetic process; endoplasmic reticulum; flavonoid biosynthetic process; heme binding; integral to membrane; iron ion binding; lignin biosynthetic process; mitochondrion; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; p-coumarate 3-hydroxylase activity; plasma membrane",PF00067;,,,,,,,,,C98A3_ARATH,Arabidopsis thaliana (Mouse-ear cress),coumarin biosynthetic process [GO:0009805]; flavonoid biosynthetic process [GO:0009813]; lignin biosynthetic process [GO:0009809]; phenylpropanoid biosynthetic process [GO:0009699] comp143868_c1_seq2,5513,44.2046,0.32905072,15,20,,0,Q6PDI5,Proteasome-associated protein ECM29 homolog (Ecm29),Proteasome-associated protein ECM29 homolog (Ecm29),GO:0030139; GO:0005783; GO:0005793; GO:0005815; GO:0005771; GO:0005634; GO:0000502,endocytic vesicle; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; microtubule organizing center; multivesicular body; nucleus; proteasome complex,PF13001;,0,CHOYP_ECM29.1.1,,,,,,,ECM29_MOUSE,Mus musculus (Mouse),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; proteasome assembly [GO:0043248] comp143868_c1_seq4,3423,43.6459,0.33379974,0,0,,0,Q6PDI5,Proteasome-associated protein ECM29 homolog (Ecm29),Proteasome-associated protein ECM29 homolog (Ecm29),GO:0030139; GO:0005783; GO:0005793; GO:0005815; GO:0005771; GO:0005634; GO:0000502,endocytic vesicle; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; microtubule organizing center; multivesicular body; nucleus; proteasome complex,PF13001;,0,CHOYP_ECM29.1.1,,,,,,,ECM29_MOUSE,Mus musculus (Mouse),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; proteasome assembly [GO:0043248] comp143870_c0_seq2,618,43.8511,0.57597305,0,74,,2.00E-10,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp143871_c4_seq1,1914,39.9164,0.3972261,562,6647,,1.00E-155,Q9R0Q6,Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329),Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329),GO:0005885; GO:0005737; GO:0030833,Arp2/3 protein complex; cytoplasm; regulation of actin filament polymerization,PF00400;,4.00E-82,CHOYP_ARC1A.1.1,2.00E-128,ruditapes_c2869,,,,,ARC1A_MOUSE,Mus musculus (Mouse),Arp2/3 complex-mediated actin nucleation [GO:0034314] comp143873_c0_seq1,1654,32.8295,0.36109761,35,228,,,,,,,,,3.00E-19,CHOYP_LOC100567790.1.1,,,,,,,,, comp143873_c0_seq2,1681,32.8971,0.37628649,30,155,,4.00E-13,Q96KC8,DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1),DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1),GO:0001671; GO:0003677; GO:0003682; GO:0005783; GO:0005789; GO:0016021; GO:0045861; GO:0031965; GO:0006457; GO:0050708; GO:0006417,ATPase activator activity; DNA binding; chromatin binding; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; negative regulation of proteolysis; nuclear membrane; protein folding; regulation of protein secretion; regulation of translation,PF00226;PF00249;,,,,,,,,,DNJC1_HUMAN,Homo sapiens (Human),negative regulation of proteolysis [GO:0045861]; protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417] comp143873_c0_seq3,1272,39.8585,0.28879328,10,70,,6.00E-26,Q61712,DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1),DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1),GO:0003677; GO:0051087; GO:0003682; GO:0005788; GO:0005789; GO:0016021; GO:0031965; GO:0005634; GO:0006457; GO:0050708; GO:0006417; GO:0043022,DNA binding; chaperone binding; chromatin binding; endoplasmic reticulum lumen; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; nucleus; protein folding; regulation of protein secretion; regulation of translation; ribosome binding,PF00226;PF00249;,5.00E-28,CHOYP_LOC100567790.1.1,,,,,,,DNJC1_MOUSE,Mus musculus (Mouse),protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417] comp143873_c0_seq4,1031,41.1251,0.23809546,4,0,,2.00E-31,Q96KC8,DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1),DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1),GO:0001671; GO:0003677; GO:0003682; GO:0005783; GO:0005789; GO:0016021; GO:0045861; GO:0031965; GO:0006457; GO:0050708; GO:0006417,ATPase activator activity; DNA binding; chromatin binding; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; negative regulation of proteolysis; nuclear membrane; protein folding; regulation of protein secretion; regulation of translation,PF00226;PF00249;,,,,,,,,,DNJC1_HUMAN,Homo sapiens (Human),negative regulation of proteolysis [GO:0045861]; protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417] comp143874_c0_seq1,2473,38.7384,0.59764501,393,1917,,2.00E-124,O43913,Origin recognition complex subunit 5,Origin recognition complex subunit 5,GO:0005524; GO:0006270; GO:0003688; GO:0000082; GO:0005737; GO:0005664; GO:0005654; GO:0000166,ATP binding; DNA replication initiation; DNA replication origin binding; G1/S transition of mitotic cell cycle; cytoplasm; nuclear origin of replication recognition complex; nucleoplasm; nucleotide binding,PF14630;,1.00E-95,CHOYP_RELN.3.4,,,,,,,ORC5_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082] comp143874_c0_seq3,438,40.6393,0.66810748,23,77,,,,,,,,,9.00E-38,CHOYP_LOC100377892.2.2,,,,,,,,, comp143875_c0_seq1,3755,44.7403,0.40170487,0,0,,1.00E-112,Q9P2K1,Coiled-coil and C2 domain-containing protein 2A,Coiled-coil and C2 domain-containing protein 2A,GO:0036038; GO:0042384; GO:0005737; GO:0005932; GO:0007224,TCTN-B9D complex; cilium assembly; cytoplasm; microtubule basal body; smoothened signaling pathway,PF00168;PF15625;,4.00E-47,CHOYP_CC2D2A.1.2,,,,,,,C2D2A_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224] comp143875_c0_seq11,4510,44.1242,0.40588323,0,0,,,,,,,,,5.00E-47,CHOYP_CC2D2A.1.2,,,,,,,,, comp143875_c0_seq12,4533,45.3122,0.42835234,0,0,,,,,,,,,3.00E-25,CHOYP_CC2D2A.2.2,,,,,,,,, comp143875_c0_seq13,4497,45.3413,0.43502244,0,0,,0,Q9P2K1,Coiled-coil and C2 domain-containing protein 2A,Coiled-coil and C2 domain-containing protein 2A,GO:0036038; GO:0042384; GO:0005737; GO:0005932; GO:0007224,TCTN-B9D complex; cilium assembly; cytoplasm; microtubule basal body; smoothened signaling pathway,PF00168;PF15625;,,,,,,,,,C2D2A_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224] comp143875_c0_seq14,4691,44.8945,0.44280984,2,0,,,,,,,,,2.00E-26,CHOYP_CC2D2A.2.2,,,,,,,,, comp143875_c0_seq16,4353,44.544,0.39884928,0,0,,8.00E-133,Q9P2K1,Coiled-coil and C2 domain-containing protein 2A,Coiled-coil and C2 domain-containing protein 2A,GO:0036038; GO:0042384; GO:0005737; GO:0005932; GO:0007224,TCTN-B9D complex; cilium assembly; cytoplasm; microtubule basal body; smoothened signaling pathway,PF00168;PF15625;,5.00E-47,CHOYP_CC2D2A.1.2,,,,,,,C2D2A_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224] comp143875_c0_seq3,4654,44.8646,0.43794341,0,0,,,,,,,,,2.00E-26,CHOYP_CC2D2A.2.2,,,,,,,,, comp143875_c0_seq4,4317,44.6143,0.41435291,0,0,,7.00E-133,Q9P2K1,Coiled-coil and C2 domain-containing protein 2A,Coiled-coil and C2 domain-containing protein 2A,GO:0036038; GO:0042384; GO:0005737; GO:0005932; GO:0007224,TCTN-B9D complex; cilium assembly; cytoplasm; microtubule basal body; smoothened signaling pathway,PF00168;PF15625;,,,,,,,,,C2D2A_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224] comp143875_c0_seq5,3562,45.3397,0.40650253,0,0,,5.00E-11,Q95K30,Uncharacterized protein C10orf131 homolog,Uncharacterized protein C10orf131 homolog,,,,4.00E-47,CHOYP_CC2D2A.1.2,,,,,,,CJ131_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143875_c0_seq6,1404,40.7407,0.50444487,281,336,,6.00E-26,Q6DHV5,Protein CC2D2B,Protein CC2D2B,,,,1.00E-68,CHOYP_CC2D2A.1.2,4.00E-34,ruditapes_c23576,,,,,C2D2B_HUMAN,Homo sapiens (Human), comp143875_c0_seq8,3598,45.3029,0.39833002,0,0,,5.00E-11,Q95K30,Uncharacterized protein C10orf131 homolog,Uncharacterized protein C10orf131 homolog,,,,,,,,,,,,CJ131_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143875_c0_seq9,4474,44.0992,0.40437316,0,0,,1.00E-132,Q9P2K1,Coiled-coil and C2 domain-containing protein 2A,Coiled-coil and C2 domain-containing protein 2A,GO:0036038; GO:0042384; GO:0005737; GO:0005932; GO:0007224,TCTN-B9D complex; cilium assembly; cytoplasm; microtubule basal body; smoothened signaling pathway,PF00168;PF15625;,,,,,,,,,C2D2A_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224] comp143876_c0_seq1,3233,36.7151,0.50808392,19,16,,0,A1A5Q4,UPF0704 protein C6orf165 homolog,UPF0704 protein C6orf165 homolog,,,PF12018;,,,2.00E-123,ruditapes_c10943,,,,,CF165_RAT,Rattus norvegicus (Rat), comp143876_c0_seq7,3260,36.6258,0.50623359,124,33,,0,A1A5Q4,UPF0704 protein C6orf165 homolog,UPF0704 protein C6orf165 homolog,,,PF12018;,0,CHOYP_LOC100369566.1.1,,,7.00E-86,BQ426960.p.cg.6,5,,CF165_RAT,Rattus norvegicus (Rat), comp143876_c0_seq8,1627,34.0504,0.55350275,0,0,,,,,,,,,6.00E-66,CHOYP_LOC100369566.1.1,,,,,,,,, comp143877_c0_seq2,2261,38.9651,0.32666962,118,64,,2.00E-73,Q568B7,Glycosyltransferase-like domain-containing protein 1,Glycosyltransferase-like domain-containing protein 1,GO:0009058; GO:0016757,"biosynthetic process; transferase activity, transferring glycosyl groups",PF12038;PF00534;,5.00E-31,CHOYP_BRAFLDRAFT_120634.1.1,,,,,,,GTDC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143877_c0_seq3,1568,38.5204,0.3806784,21,55,,8.00E-65,Q53E76,Glycosyltransferase-like domain-containing protein 1,Glycosyltransferase-like domain-containing protein 1,GO:0009058; GO:0016757,"biosynthetic process; transferase activity, transferring glycosyl groups",PF12038;PF00534;,,,,,,,,,GTDC1_RAT,Rattus norvegicus (Rat), comp143878_c0_seq1,2873,38.1135,0.52549323,165,1139,,2.00E-165,Q9VU68,Actin-interacting protein 1 (AIP1) (Protein flare),Actin-interacting protein 1 (AIP1) (Protein flare),GO:0003779; GO:0030042; GO:0005737; GO:0005856; GO:0001736; GO:0035317; GO:0006909; GO:0030834; GO:0045214,actin binding; actin filament depolymerization; cytoplasm; cytoskeleton; establishment of planar polarity; imaginal disc-derived wing hair organization; phagocytosis; regulation of actin filament depolymerization; sarcomere organization,PF00400;,,,,,,,,,WDR1_DROME,Drosophila melanogaster (Fruit fly),actin filament depolymerization [GO:0030042]; border follicle cell migration [GO:0007298]; establishment of planar polarity [GO:0001736]; imaginal disc-derived wing hair organization [GO:0035317]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; phagocytosis [GO:0006909]; regulation of actin filament depolymerization [GO:0030834]; regulation of actin filament polymerization [GO:0030833]; sarcomere organization [GO:0045214] comp143878_c0_seq2,1565,36.869,0.5283403,45,183,,1.00E-07,Q6FVD3,Protein HIR1,Protein HIR1,GO:0003682; GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07569;PF09453;PF00400;,,,,,,,,,HIR1_CANGA,Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata),chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp143879_c1_seq1,6539,36.0911,0.52026021,1869,6661,,2.00E-149,P35953,Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),GO:0005509; GO:0008203; GO:0005905; GO:0034436; GO:0034437; GO:0016021; GO:0006869; GO:0000122; GO:1900006; GO:0038025; GO:0021517; GO:0034361; GO:0034189; GO:0034447; GO:0030229,calcium ion binding; cholesterol metabolic process; coated pit; glycoprotein transport; glycoprotein transporter activity; integral to membrane; lipid transport; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite development; reelin receptor activity; ventral spinal cord development; very-low-density lipoprotein particle; very-low-density lipoprotein particle binding; very-low-density lipoprotein particle clearance; very-low-density lipoprotein particle receptor activity,PF07645;PF00057;PF00058;,,,,,,,,,VLDLR_RABIT,Oryctolagus cuniculus (Rabbit),cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; lipid transport [GO:0006869]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] comp143879_c1_seq2,5886,36.6633,0.50820054,2,87,,2.00E-150,P98165,Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (Vitellogenin receptor) (VTG receptor),Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (Vitellogenin receptor) (VTG receptor),GO:0005509; GO:0008203; GO:0005905; GO:0016021; GO:0006869; GO:0030228; GO:0021517; GO:0034361,calcium ion binding; cholesterol metabolic process; coated pit; integral to membrane; lipid transport; lipoprotein particle receptor activity; ventral spinal cord development; very-low-density lipoprotein particle,PF07645;PF00057;PF00058;,,,,,,,,,VLDLR_CHICK,Gallus gallus (Chicken),cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]; ventral spinal cord development [GO:0021517] comp143879_c1_seq3,5924,36.6138,0.5212745,152,423,,2.00E-150,P98165,Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (Vitellogenin receptor) (VTG receptor),Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (Vitellogenin receptor) (VTG receptor),GO:0005509; GO:0008203; GO:0005905; GO:0016021; GO:0006869; GO:0030228; GO:0021517; GO:0034361,calcium ion binding; cholesterol metabolic process; coated pit; integral to membrane; lipid transport; lipoprotein particle receptor activity; ventral spinal cord development; very-low-density lipoprotein particle,PF07645;PF00057;PF00058;,,,,,,,,,VLDLR_CHICK,Gallus gallus (Chicken),cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]; ventral spinal cord development [GO:0021517] comp143880_c0_seq1,2649,34.2771,0.42948497,337,831,,,,,,,,,7.00E-106,CHOYP_TRIADDRAFT_25769.1.1,,,,,,,,, comp143880_c0_seq2,2459,34.8109,0.3812181,110,255,,6.00E-73,Q5ZKX1,Charged multivesicular body protein 1b (Chromatin-modifying protein 1b) (CHMP1b),Charged multivesicular body protein 1b (Chromatin-modifying protein 1b) (CHMP1b),GO:0005829; GO:0031902; GO:0015031,cytosol; late endosome membrane; protein transport,PF03357;,6.00E-106,CHOYP_TRIADDRAFT_25769.1.1,,,,,,,CHM1B_CHICK,Gallus gallus (Chicken),protein transport [GO:0015031]; vacuolar transport [GO:0007034] comp143881_c0_seq1,1967,43.3655,0.44638008,0,10,,1.00E-124,O00418,Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase),Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase),GO:0005524; GO:0005509; GO:0005516; GO:0005829; GO:0004686; GO:0008286; GO:0046777; GO:0031952; GO:0008135; GO:0006414,"ATP binding; calcium ion binding; calmodulin binding; cytosol; elongation factor-2 kinase activity; insulin receptor signaling pathway; protein autophosphorylation; regulation of protein autophosphorylation; translation factor activity, nucleic acid binding; translational elongation",PF02816;PF08238;,1.00E-113,CHOYP_LOC100376880.1.1,,,,,,,EF2K_HUMAN,Homo sapiens (Human),cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637]; translational elongation [GO:0006414] comp143883_c1_seq2,1750,34.8571,0.65006955,20,341,,2.00E-45,Q9UK45,U6 snRNA-associated Sm-like protein LSm7,U6 snRNA-associated Sm-like protein LSm7,GO:0017070; GO:0005829; GO:0043928; GO:0000398; GO:0005634; GO:0005681,"U6 snRNA binding; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; mRNA splicing, via spliceosome; nucleus; spliceosomal complex",PF01423;,3.00E-57,CHOYP_LSM7.1.1,,,,,,,LSM7_HUMAN,Homo sapiens (Human),"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]" comp143885_c2_seq1,1438,42.9068,0.59306768,272,1223,,8.00E-87,Q66I12,Coiled-coil domain-containing protein 47,Coiled-coil domain-containing protein 47,GO:0016021,integral to membrane,PF07946;,7.00E-90,CHOYP_LOC100374993.1.1,,,,,,,CCD47_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp143887_c0_seq2,1934,44.8811,0.56168375,28,555,,2.00E-120,P23606,Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1),Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1),GO:0031224; GO:0031424; GO:0046872; GO:0018149; GO:0003810,intrinsic to membrane; keratinization; metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,1.00E-55,CHOYP_NEMVEDRAFT_V1G97278.2.2,,,,,,,TGM1_RAT,Rattus norvegicus (Rat),keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] comp143889_c0_seq1,4090,38.1174,0.53734262,1867,1446,,2.00E-106,O54781,SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal],SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal],GO:0071889; GO:0005524; GO:0001525; GO:0030154; GO:0005737; GO:0007243; GO:0000287; GO:0045071; GO:0035063; GO:0005634; GO:0045787; GO:0008284; GO:0010628; GO:0043525; GO:0045070; GO:0004674; GO:0000245,14-3-3 protein binding; ATP binding; angiogenesis; cell differentiation; cytoplasm; intracellular protein kinase cascade; magnesium ion binding; negative regulation of viral genome replication; nuclear speck organization; nucleus; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of gene expression; positive regulation of neuron apoptotic process; positive regulation of viral genome replication; protein serine/threonine kinase activity; spliceosomal complex assembly,PF00069;,2.00E-133,CHOYP_SRPK2.1.1,,,,,,,SRPK2_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] comp143891_c0_seq1,2879,43.8347,0.50184508,87,107,,0,Q8IYB7,DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-),DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-),GO:0000175; GO:0003723; GO:0051301; GO:0000932; GO:0010587; GO:0051306; GO:0008285; GO:0000291; GO:0005844; GO:1990074; GO:0019827,"3'-5'-exoribonuclease activity; RNA binding; cell division; cytoplasmic mRNA processing body; miRNA catabolic process; mitotic sister chromatid separation; negative regulation of cell proliferation; nuclear-transcribed mRNA catabolic process, exonucleolytic; polysome; polyuridylation-dependent mRNA catabolic process; stem cell maintenance",,8.00E-150,CHOYP_LOC100372341.1.1,,,,,,,DI3L2_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; miRNA catabolic process [GO:0010587]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell proliferation [GO:0008285]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; stem cell population maintenance [GO:0019827]" comp143891_c0_seq2,1482,45.2767,0.57913931,15,19,,3.00E-24,P54084,Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog) (Fragment),Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog) (Fragment),GO:0003723; GO:0016070; GO:0005737; GO:0008859; GO:0090305,RNA binding; RNA metabolic process; cytoplasm; exoribonuclease II activity; nucleic acid phosphodiester bond hydrolysis,PF08461;PF08206;,,,,,,,,,RNR_THIFE,Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans), comp143891_c0_seq4,638,44.2006,0.54739364,55,45,,6.00E-09,P81021,Vigilin,Vigilin,GO:0003723; GO:0005737,RNA binding; cytoplasm,PF00013;,,,,,,,,,VIGLN_CHICK,Gallus gallus (Chicken), comp143892_c1_seq1,3229,35.2431,0.52367061,0,0,,1.00E-27,Q3ZBL5,"Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription)","Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription)",GO:0004045; GO:0005829; GO:0005739; GO:2000811; GO:0010629; GO:2000210,aminoacyl-tRNA hydrolase activity; cytosol; mitochondrion; negative regulation of anoikis; negative regulation of gene expression; positive regulation of anoikis,PF01981;,5.00E-13,CHOYP_PTH2.1.1,,,,,,,PTH2_BOVIN,Bos taurus (Bovine), comp143892_c1_seq6,3202,35.1655,0.52050937,0,0,,1.00E-27,Q3ZBL5,"Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription)","Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription)",GO:0004045; GO:0005829; GO:0005739; GO:2000811; GO:0010629; GO:2000210,aminoacyl-tRNA hydrolase activity; cytosol; mitochondrion; negative regulation of anoikis; negative regulation of gene expression; positive regulation of anoikis,PF01981;,5.00E-13,CHOYP_PTH2.1.1,3.00E-64,ruditapes_c16850,,,,,PTH2_BOVIN,Bos taurus (Bovine), comp143893_c1_seq1,4948,47.7567,0.6205923,34,63,,0,Q80TP3,"E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)","E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)",GO:0006281; GO:0003723; GO:0005737; GO:2000780; GO:1901315; GO:0005634; GO:0050847; GO:0042787; GO:0006974; GO:0004842; GO:0008270,DNA repair; RNA binding; cytoplasm; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleus; progesterone receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity; zinc ion binding,PF11547;PF00632;PF00658;,,,,,,,,,UBR5_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of protein import into nucleus, translocation [GO:0033160]; progesterone receptor signaling pathway [GO:0050847]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]" comp143893_c1_seq2,4889,47.9239,0.62727403,15,33,,5.00E-11,Q9H361,Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein),Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein),GO:0005737; GO:0016071; GO:0000166; GO:0008143,cytoplasm; mRNA metabolic process; nucleotide binding; poly(A) RNA binding,PF00658;PF00076;,0,CHOYP_UBR5.1.1,6.00E-19,ruditapes_c30593,,,,,PABP3_HUMAN,Homo sapiens (Human),mRNA metabolic process [GO:0016071] comp143893_c1_seq3,520,52.6923,0.45701923,0,0,,1.00E-30,P51592,E3 ubiquitin-protein ligase hyd (EC 6.3.2.-) (Protein hyperplastic discs),E3 ubiquitin-protein ligase hyd (EC 6.3.2.-) (Protein hyperplastic discs),GO:0003723; GO:0048749; GO:0005737; GO:0007455; GO:0008585; GO:0007446; GO:0007112; GO:0045879; GO:0005634; GO:0042787; GO:0030162; GO:0007289; GO:0004842; GO:0008270,RNA binding; compound eye development; cytoplasm; eye-antennal disc morphogenesis; female gonad development; imaginal disc growth; male meiosis cytokinesis; negative regulation of smoothened signaling pathway; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of proteolysis; spermatid nucleus differentiation; ubiquitin-protein ligase activity; zinc ion binding,PF11547;PF00632;PF00658;,6.00E-28,CHOYP_UBR5.1.1,,,,,,,HYD_DROME,Drosophila melanogaster (Fruit fly),compound eye development [GO:0048749]; eye-antennal disc morphogenesis [GO:0007455]; female gonad development [GO:0008585]; germ cell development [GO:0007281]; imaginal disc development [GO:0007444]; imaginal disc growth [GO:0007446]; male meiosis cytokinesis [GO:0007112]; negative regulation of smoothened signaling pathway [GO:0045879]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell proliferation [GO:0042127]; regulation of proteolysis [GO:0030162]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283] comp143895_c0_seq2,2519,28.1461,0.36329276,0,0,,,,,,,,,7.00E-42,CHOYP_LOC100562878.2.2,,,,,,,,, comp143895_c0_seq3,2559,27.9797,0.38202059,40,88,,1.00E-33,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,3.00E-27,CHOYP_LOC100555596.1.2,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143895_c0_seq4,2625,28.3429,0.3816861,0,0,,5.00E-34,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,6.00E-56,CHOYP_LOC100562878.2.2,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp143895_c0_seq5,1454,29.2985,0.41991362,76,213,,2.00E-06,P16425,Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,3.00E-37,CHOYP_LOC100536368.2.2,2.00E-36,ruditapes_c17285,,,,,Y2R2_DROME,Drosophila melanogaster (Fruit fly), comp143896_c1_seq1,3988,41.4243,0.48076173,53,12,,,,,,,,,0,CHOYP_LOC578169.1.1,,,,,,,,, comp143896_c1_seq3,3928,41.5733,0.48422781,0,0,,2.00E-105,Q5T1B0,Axonemal dynein light chain domain-containing protein 1,Axonemal dynein light chain domain-containing protein 1,,,PF10211;,,,,,,,,,AXDN1_HUMAN,Homo sapiens (Human), comp143896_c1_seq5,4017,41.5982,0.51348774,30,7,,8.00E-101,Q5T1B0,Axonemal dynein light chain domain-containing protein 1,Axonemal dynein light chain domain-containing protein 1,,,PF10211;,0,CHOYP_LOC578169.1.1,,,,,,,AXDN1_HUMAN,Homo sapiens (Human), comp143897_c1_seq1,3026,45.0099,0.46465378,16,0,,2.00E-22,Q9BE52,CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48),CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48),GO:0005794; GO:0007420; GO:0051297; GO:0007059; GO:0000132; GO:0005874; GO:0001578; GO:0046600; GO:0022008; GO:0000242; GO:0048471; GO:0045893; GO:0019901; GO:0090231; GO:0000922; GO:0044212,"Golgi apparatus; brain development; centrosome organization; chromosome segregation; establishment of mitotic spindle orientation; microtubule; microtubule bundle formation; negative regulation of centriole replication; neurogenesis; pericentriolar material; perinuclear region of cytoplasm; positive regulation of transcription, DNA-dependent; protein kinase binding; regulation of spindle checkpoint; spindle pole; transcription regulatory region DNA binding",PF07989;,1.00E-27,CHOYP_TVAG_268110.12.13,,,,,,,CK5P2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"brain development [GO:0007420]; centrosome organization [GO:0051297]; chromosome segregation [GO:0007059]; establishment of mitotic spindle orientation [GO:0000132]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule organizing center organization [GO:0031023]; negative regulation of centriole replication [GO:0046600]; neurogenesis [GO:0022008]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of spindle checkpoint [GO:0090231]" comp143897_c1_seq3,3098,45.0613,0.46607349,7,0,,3.00E-22,Q9BE52,CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48),CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48),GO:0005794; GO:0007420; GO:0051297; GO:0007059; GO:0000132; GO:0005874; GO:0001578; GO:0046600; GO:0022008; GO:0000242; GO:0048471; GO:0045893; GO:0019901; GO:0090231; GO:0000922; GO:0044212,"Golgi apparatus; brain development; centrosome organization; chromosome segregation; establishment of mitotic spindle orientation; microtubule; microtubule bundle formation; negative regulation of centriole replication; neurogenesis; pericentriolar material; perinuclear region of cytoplasm; positive regulation of transcription, DNA-dependent; protein kinase binding; regulation of spindle checkpoint; spindle pole; transcription regulatory region DNA binding",PF07989;,6.00E-25,CHOYP_TVAG_268110.2.13,,,,,,,CK5P2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"brain development [GO:0007420]; centrosome organization [GO:0051297]; chromosome segregation [GO:0007059]; establishment of mitotic spindle orientation [GO:0000132]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule organizing center organization [GO:0031023]; negative regulation of centriole replication [GO:0046600]; neurogenesis [GO:0022008]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of spindle checkpoint [GO:0090231]" comp143897_c1_seq4,3065,45.0897,0.46431563,0,0,,4.00E-08,P54623,Centrosomin (Protein arrow),Centrosomin (Protein arrow),GO:0008356; GO:0055059; GO:0007417; GO:0005814; GO:0007099; GO:0005929; GO:0040016; GO:0016321; GO:0005875; GO:0005932; GO:0008017; GO:0007494; GO:0007067; GO:0007052; GO:0000242; GO:0007422; GO:0008594; GO:0007279; GO:0030997; GO:0000922,asymmetric cell division; asymmetric neuroblast division; central nervous system development; centriole; centriole replication; cilium; embryonic cleavage; female meiosis chromosome segregation; microtubule associated complex; microtubule basal body; microtubule binding; midgut development; mitosis; mitotic spindle organization; pericentriolar material; peripheral nervous system development; photoreceptor cell morphogenesis; pole cell formation; regulation of centriole-centriole cohesion; spindle pole,PF07989;,1.00E-27,CHOYP_TVAG_268110.12.13,,,,,,,CNN_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; central nervous system development [GO:0007417]; centriole replication [GO:0007099]; centrosome cycle [GO:0007098]; centrosome organization [GO:0051297]; embryonic cleavage [GO:0040016]; female meiosis chromosome segregation [GO:0016321]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; midgut development [GO:0007494]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; nuclear division [GO:0000280]; peripheral nervous system development [GO:0007422]; photoreceptor cell morphogenesis [GO:0008594]; pole cell formation [GO:0007279]; regulation of centriole-centriole cohesion [GO:0030997] comp143900_c0_seq1,5141,40.3229,0.97962259,7,18,,9.00E-37,P12247,Complement C3 alpha chain (Fragment),Complement C3 alpha chain (Fragment),GO:0006957; GO:0006958; GO:0005615; GO:0006954,"complement activation, alternative pathway; complement activation, classical pathway; extracellular space; inflammatory response",PF07678;PF07677;PF01759;PF10569;,,,,,,,,,CO3_RABIT,Oryctolagus cuniculus (Rabbit),"complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]" comp143900_c0_seq3,5720,40.3671,0.99544794,131,345,,2.00E-129,P98093,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] (Fragment),Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] (Fragment),GO:0006957; GO:0006958; GO:0004866; GO:0005615; GO:0006954; GO:0010951,"complement activation, alternative pathway; complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; inflammatory response; negative regulation of endopeptidase activity",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),"complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]" comp143901_c1_seq1,6915,40.564,0.46064565,0,0,,3.00E-124,Q68CP9,AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200),AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200),GO:0003677; GO:0016568; GO:0046872; GO:0006337; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; metal ion binding; nucleosome disassembly; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF02257;,1.00E-30,CHOYP_ARID2.1.2,,,,,,,ARID2_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143901_c1_seq2,6379,42.1226,0.46657582,0,0,,2.00E-63,Q09441,ARID domain-containing protein C08B11.3,SWI/SNF nucleosome remodeling complex component (ARID domain-containing protein C08B11.3),GO:0003677; GO:0005622; GO:0046872; GO:0006355,"DNA binding; intracellular; metal ion binding; regulation of transcription, DNA-dependent",PF01388;,1.00E-30,CHOYP_ARID2.1.2,,,,,,,YP83_CAEEL,Caenorhabditis elegans,"regulation of transcription, DNA-templated [GO:0006355]" comp143901_c1_seq3,7065,40.736,0.4640782,0,0,,5.00E-124,Q68CP9,AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200),AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200),GO:0003677; GO:0016568; GO:0046872; GO:0006337; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; metal ion binding; nucleosome disassembly; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF02257;,6.00E-29,CHOYP_ARID2.2.2,,,,,,,ARID2_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143901_c1_seq4,829,42.5814,0.99077444,0,0,,2.00E-06,Q8NFD5,AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R),AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R),GO:0003677; GO:0016514; GO:0048096; GO:0007399; GO:0003713; GO:0006351,"DNA binding; SWI/SNF complex; chromatin-mediated maintenance of transcription; nervous system development; transcription coactivator activity; transcription, DNA-dependent",PF01388;PF12031;,,,,,,,,,ARI1B_HUMAN,Homo sapiens (Human),"chromatin-mediated maintenance of transcription [GO:0048096]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]" comp143901_c1_seq5,6229,41.965,0.4632681,0,0,,9.00E-125,Q68CP9,AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200),AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200),GO:0003677; GO:0016568; GO:0046872; GO:0006337; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; metal ion binding; nucleosome disassembly; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01388;PF02257;,1.00E-30,CHOYP_ARID2.1.2,,,,,,,ARID2_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143902_c1_seq1,1237,40.4204,0.55494401,235,2233,,6.00E-160,Q3T0Q3,DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II subunit C),DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II subunit C),GO:0003677; GO:0005665; GO:0003899; GO:0015630; GO:0006366,"DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; microtubule cytoskeleton; transcription from RNA polymerase II promoter",PF01000;PF01193;,1.00E-143,CHOYP_RPB3.1.1,,,,,,,RPB3_BOVIN,Bos taurus (Bovine),transcription from RNA polymerase II promoter [GO:0006366] comp143903_c0_seq1,2955,41.7259,0.6981616,27,129,,1.00E-143,Q68F35,Sodium-dependent phosphate transporter 1-A (Solute carrier family 20 member 1-A),Sodium-dependent phosphate transporter 1-A (Solute carrier family 20 member 1-A),GO:0005315; GO:0016021; GO:0006817; GO:0015293,inorganic phosphate transmembrane transporter activity; integral to membrane; phosphate ion transport; symporter activity,PF01384;,4.00E-52,CHOYP_BRAFLDRAFT_120634.1.1,,,,,,,S20AA_XENLA,Xenopus laevis (African clawed frog),phosphate ion transport [GO:0006817] comp143903_c0_seq2,2935,41.6354,0.69739677,7,19,,1.00E-143,Q68F35,Sodium-dependent phosphate transporter 1-A (Solute carrier family 20 member 1-A),Sodium-dependent phosphate transporter 1-A (Solute carrier family 20 member 1-A),GO:0005315; GO:0016021; GO:0006817; GO:0015293,inorganic phosphate transmembrane transporter activity; integral to membrane; phosphate ion transport; symporter activity,PF01384;,,,,,,,,,S20AA_XENLA,Xenopus laevis (African clawed frog),phosphate ion transport [GO:0006817] comp143903_c0_seq3,2408,41.8189,0.63697999,0,10,,4.00E-12,O34436,Probable low-affinity inorganic phosphate transporter,Probable low-affinity inorganic phosphate transporter,GO:0005315; GO:0016021; GO:0006817; GO:0005886,inorganic phosphate transmembrane transporter activity; integral to membrane; phosphate ion transport; plasma membrane,PF01384;,3.00E-52,CHOYP_BRAFLDRAFT_120634.1.1,,,,,,,PIT_BACSU,Bacillus subtilis (strain 168),phosphate ion transmembrane transport [GO:0035435] comp143903_c0_seq4,1868,39.454,0.6506677,6,0,,1.00E-19,O30499,Probable low-affinity inorganic phosphate transporter,Probable low-affinity inorganic phosphate transporter,GO:0005315; GO:0016021; GO:0006817; GO:0005886,inorganic phosphate transmembrane transporter activity; integral to membrane; phosphate ion transport; plasma membrane,PF01384;,,,,,,,,,PIT_RHIME,Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti),phosphate ion transport [GO:0006817] comp143904_c0_seq1,5201,41.6458,0.45139011,47,46,,7.00E-91,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,1.00E-23,CHOYP_PARP14.16.22,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143904_c0_seq10,2984,41.555,0.40455758,0,0,,2.00E-34,Q9WYX8,Uncharacterized protein TM_0508,Uncharacterized protein TM_0508,GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009378,ATP binding; DNA binding; DNA recombination; DNA repair; DNA replication; four-way junction helicase activity,PF16193;PF01661;PF12002;PF05496;,,,3.00E-26,ruditapes2_c2361,,,,,Y508_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp143904_c0_seq4,2840,40.3169,0.45314411,0,0,,8.00E-43,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143904_c0_seq5,2336,40.2397,0.39251847,0,0,,1.00E-34,Q9WYX8,Uncharacterized protein TM_0508,Uncharacterized protein TM_0508,GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009378,ATP binding; DNA binding; DNA recombination; DNA repair; DNA replication; four-way junction helicase activity,PF16193;PF01661;PF12002;PF05496;,,,,,,,,,Y508_THEMA,Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp143904_c0_seq9,4366,41.5483,0.47167558,17,3,,2.00E-42,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143906_c1_seq9,562,41.8149,0.38097865,4,51,,2.00E-22,Q27597,NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4),NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4),GO:0010181; GO:0003958; GO:0005829; GO:0005789; GO:0005506; GO:0005811; GO:0016709,"FMN binding; NADPH-hemoprotein reductase activity; cytosol; endoplasmic reticulum membrane; iron ion binding; lipid particle; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen",PF00667;PF00258;PF00175;,,,,,,,,,NCPR_DROME,Drosophila melanogaster (Fruit fly), comp143907_c5_seq1,3251,42.0486,0.50050295,8,0,,,,,,,,,0,CHOYP_LOC100372826.1.1,,,,,,,,, comp143907_c5_seq3,3527,41.9337,0.48936749,15,0,,4.00E-106,Q95LZ5,Tetratricopeptide repeat protein 16 (TPR repeat protein 16),Tetratricopeptide repeat protein 16 (TPR repeat protein 16),,,PF00515;,,,,,,,,,TTC16_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143907_c5_seq4,3547,41.8382,0.49523953,0,0,,,,,,,,,0,CHOYP_LOC100372826.1.1,,,,,,,,, comp143907_c5_seq7,3087,41.8529,0.50349955,0,0,,1.00E-106,Q95LZ5,Tetratricopeptide repeat protein 16 (TPR repeat protein 16),Tetratricopeptide repeat protein 16 (TPR repeat protein 16),,,PF00515;,,,,,,,,,TTC16_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143907_c5_seq8,3363,41.6295,0.49405203,0,0,,,,,,,,,0,CHOYP_LOC100372826.1.1,,,,,,,,, comp143907_c5_seq9,3383,41.6199,0.49836778,0,0,,5.00E-106,Q95LZ5,Tetratricopeptide repeat protein 16 (TPR repeat protein 16),Tetratricopeptide repeat protein 16 (TPR repeat protein 16),,,PF00515;,,,,,,,,,TTC16_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp143909_c1_seq1,2220,41.0811,0.41626232,223,1736,,3.00E-172,Q17QZ7,Tetratricopeptide repeat protein 27 (TPR repeat protein 27),Tetratricopeptide repeat protein 27 (TPR repeat protein 27),,,,6.00E-68,CHOYP_TTC27.1.1,,,,,,,TTC27_BOVIN,Bos taurus (Bovine), comp143910_c0_seq1,4409,42.4813,0.44487244,9,14,,1.00E-64,O75140,DEP domain-containing protein 5,DEP domain-containing protein 5,GO:0005096; GO:0005829; GO:0035556; GO:0005765; GO:0048471; GO:0043547,GTPase activator activity; cytosol; intracellular signal transduction; lysosomal membrane; perinuclear region of cytoplasm; positive regulation of GTPase activity,PF00610;PF12257;,1.00E-34,CHOYP_AGAP_AGAP002554.1.1,,,,,,,DEPD5_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007] comp143910_c0_seq2,2424,35.8498,0.40300971,30,7,,5.00E-08,Q75DV2,Vacuolar membrane-associated protein IML1,Vacuolar membrane-associated protein IML1,GO:0035556; GO:0005774,intracellular signal transduction; vacuolar membrane,PF00610;PF12257;,2.00E-43,CHOYP_LOC100121949.1.2,,,,,,,IML1_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),intracellular signal transduction [GO:0035556]; regulation of autophagosome assembly [GO:2000785] comp143910_c0_seq3,4295,42.2817,0.43529823,15,21,,6.00E-66,O75140,DEP domain-containing protein 5,DEP domain-containing protein 5,GO:0005096; GO:0005829; GO:0035556; GO:0005765; GO:0048471; GO:0043547,GTPase activator activity; cytosol; intracellular signal transduction; lysosomal membrane; perinuclear region of cytoplasm; positive regulation of GTPase activity,PF00610;PF12257;,2.00E-33,CHOYP_LOC100121949.2.2,,,,,,,DEPD5_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007] comp143910_c0_seq5,2637,39.325,0.40824205,0,0,,1.00E-13,Q5AW24,Vacuolar membrane-associated protein iml1,Vacuolar membrane-associated protein iml1,GO:0035556; GO:0005774,intracellular signal transduction; vacuolar membrane,PF00610;PF12257;,2.00E-43,CHOYP_LOC100121949.1.2,,,,,,,IML1_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),intracellular signal transduction [GO:0035556] comp143911_c0_seq1,3043,39.6648,0.44315165,92,822,,2.00E-179,Q803A6,Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein),Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein),GO:0006261; GO:0051301; GO:0003682; GO:0007067; GO:0000084; GO:0005634; GO:0007062,DNA-dependent DNA replication; cell division; chromatin binding; mitosis; mitotic S phase; nucleus; sister chromatid cohesion,PF09739;,,,,,,,,,MCMBP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; DNA-dependent DNA replication [GO:0006261]; mitotic nuclear division [GO:0007067]; sister chromatid cohesion [GO:0007062] comp143911_c0_seq2,3025,39.6364,0.4296166,124,538,,2.00E-179,Q803A6,Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein),Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein),GO:0006261; GO:0051301; GO:0003682; GO:0007067; GO:0000084; GO:0005634; GO:0007062,DNA-dependent DNA replication; cell division; chromatin binding; mitosis; mitotic S phase; nucleus; sister chromatid cohesion,PF09739;,1.00E-27,CHOYP_MCMBP.2.2,,,,,,,MCMBP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; DNA-dependent DNA replication [GO:0006261]; mitotic nuclear division [GO:0007067]; sister chromatid cohesion [GO:0007062] comp143913_c0_seq1,3614,39.845,0.48146415,612,2206,,0,Q803I8,E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1),E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1),GO:0030433; GO:0005789; GO:0016021; GO:0016874; GO:0018279; GO:0016567; GO:0008270,ER-associated protein catabolic process; endoplasmic reticulum membrane; integral to membrane; ligase activity; protein N-linked glycosylation via asparagine; protein ubiquitination; zinc ion binding,PF13639;,7.00E-164,CHOYP_LOC101157789.1.1,,,,,,,SYVN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein N-linked glycosylation via asparagine [GO:0018279]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp143915_c0_seq1,1104,46.6486,0.45159423,1,0,,3.00E-55,Q86C65,Target of rapamycin (EC 2.7.1.-),Target of rapamycin (EC 2.7.1.-),GO:0005524; GO:0031932; GO:0007049; GO:0006935; GO:0008144; GO:0004674,ATP binding; TORC2 complex; cell cycle; chemotaxis; drug binding; protein serine/threonine kinase activity,PF11865;PF02259;PF02260;PF00454;PF08771;,1.00E-111,CHOYP_LOC580976.2.2,,,,,,,TOR_DICDI,Dictyostelium discoideum (Slime mold),cell cycle [GO:0007049]; chemotaxis [GO:0006935]; DNA repair [GO:0006281] comp143915_c0_seq11,1050,45.7143,0.47559915,0,0,,1.00E-146,Q9JKK8,Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),GO:0005524; GO:0003677; GO:0000077; GO:0006281; GO:0001741; GO:0005654; GO:0004674; GO:0043393,ATP binding; DNA binding; DNA damage checkpoint; DNA repair; XY body; nucleoplasm; protein serine/threonine kinase activity; regulation of protein binding,PF02259;PF02260;PF00454;PF08064;,,,,,,,,,ATR_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; establishment of RNA localization to telomere [GO:0097694]; negative regulation of DNA replication [GO:0008156]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of protein binding [GO:0043393]; replicative senescence [GO:0090399]" comp143915_c0_seq2,1032,45.4457,0.46999025,0,0,,2.00E-31,Q54UC0,DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),GO:0005524; GO:0003677; GO:0006975; GO:0006310; GO:0004677; GO:0005958; GO:0006302; GO:0006303; GO:0004672,ATP binding; DNA binding; DNA damage induced protein phosphorylation; DNA recombination; DNA-dependent protein kinase activity; DNA-dependent protein kinase-DNA ligase 4 complex; double-strand break repair; double-strand break repair via nonhomologous end joining; protein kinase activity,PF02259;PF02260;PF08163;PF00454;,,,,,,,,,PRKDC_DICDI,Dictyostelium discoideum (Slime mold),cellular response to DNA damage stimulus [GO:0006974]; DNA damage induced protein phosphorylation [GO:0006975]; double-strand break repair via nonhomologous end joining [GO:0006303]; protein phosphorylation [GO:0006468] comp143915_c0_seq3,3554,45.0197,0.43021225,24,96,,0,Q9DE14,Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),GO:0005524; GO:0003677; GO:0006281; GO:0005634; GO:0018105; GO:0004674,ATP binding; DNA binding; DNA repair; nucleus; peptidyl-serine phosphorylation; protein serine/threonine kinase activity,PF02259;PF02260;PF00454;PF08064;,,,,,,,,,ATR_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105] comp143915_c0_seq4,2974,45.696,0.44003137,6,3,,2.00E-51,Q9VK45,Target of rapamycin (EC 2.7.1.-),Target of rapamycin (EC 2.7.1.-),GO:0005524; GO:0007411; GO:0007049; GO:0048813; GO:0009594; GO:0008340; GO:0008144; GO:0032456; GO:0008406; GO:0035264; GO:0016242; GO:0042331; GO:0030307; GO:0045793; GO:0040018; GO:0046622; GO:0001934; GO:0090070; GO:0004672; GO:0043621; GO:2000377; GO:0006974; GO:0051124,ATP binding; axon guidance; cell cycle; dendrite morphogenesis; detection of nutrient; determination of adult lifespan; drug binding; endocytic recycling; gonad development; multicellular organism growth; negative regulation of macroautophagy; phototaxis; positive regulation of cell growth; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; positive regulation of protein phosphorylation; positive regulation of ribosome biogenesis; protein kinase activity; protein self-association; regulation of reactive oxygen species metabolic process; response to DNA damage stimulus; synaptic growth at neuromuscular junction,PF11865;PF02259;PF02260;PF00454;PF08771;,,,,,,,,,TOR_DROME,Drosophila melanogaster (Fruit fly),"apical protein localization [GO:0045176]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; dendrite morphogenesis [GO:0048813]; detection of nutrient [GO:0009594]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; endocytic recycling [GO:0032456]; germarium-derived cystoblast division [GO:0048142]; gonad development [GO:0008406]; growth [GO:0040007]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of macroautophagy [GO:0016242]; phosphorylation [GO:0016310]; phototaxis [GO:0042331]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ribosome biogenesis [GO:0090070]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of response to drug [GO:2001023]; regulation of terminal button organization [GO:2000331]; response to nutrient [GO:0007584]; somatic muscle development [GO:0007525]; synaptic growth at neuromuscular junction [GO:0051124]; terminal branching, open tracheal system [GO:0007430]" comp143915_c0_seq5,3432,45.3671,0.43855395,4,20,,0,Q9DE14,Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),GO:0005524; GO:0003677; GO:0006281; GO:0005634; GO:0018105; GO:0004674,ATP binding; DNA binding; DNA repair; nucleus; peptidyl-serine phosphorylation; protein serine/threonine kinase activity,PF02259;PF02260;PF00454;PF08064;,1.00E-148,CHOYP_LOC580976.2.2,,,,,,,ATR_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105] comp143915_c0_seq7,1086,46.5009,0.44391078,0,0,,2.00E-55,Q86C65,Target of rapamycin (EC 2.7.1.-),Target of rapamycin (EC 2.7.1.-),GO:0005524; GO:0031932; GO:0007049; GO:0006935; GO:0008144; GO:0004674,ATP binding; TORC2 complex; cell cycle; chemotaxis; drug binding; protein serine/threonine kinase activity,PF11865;PF02259;PF02260;PF00454;PF08771;,7.00E-114,CHOYP_LOC580976.2.2,,,,,,,TOR_DICDI,Dictyostelium discoideum (Slime mold),cell cycle [GO:0007049]; chemotaxis [GO:0006935]; DNA repair [GO:0006281] comp143916_c0_seq1,2429,42.1161,0.37217145,165,1227,,2.00E-87,Q5ZM41,Testis-expressed sequence 10 protein homolog,Testis-expressed sequence 10 protein homolog,GO:0071339; GO:0016021; GO:0031965; GO:0005730,MLL1 complex; integral to membrane; nuclear membrane; nucleolus,PF12333;,2.00E-11,CHOYP_TEX10.3.3,,,,,,,TEX10_CHICK,Gallus gallus (Chicken),maturation of LSU-rRNA [GO:0000470]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp143917_c0_seq1,4993,42.7599,0.53465668,22,0,,,,,,,,,2.00E-178,CHOYP_KIF24.1.1,,,,,,,,, comp143917_c0_seq2,4923,42.86,0.54417348,21,1,,5.00E-139,Q6NWW5,Kinesin-like protein KIF24,Kinesin-like protein KIF24,GO:0005524; GO:0005814; GO:0042384; GO:0005871; GO:0005874; GO:0007019; GO:0003777; GO:0007018,ATP binding; centriole; cilium assembly; kinesin complex; microtubule; microtubule depolymerization; microtubule motor activity; microtubule-based movement,PF00225;,2.00E-178,CHOYP_KIF24.1.1,,,,,,,KIF24_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019] comp143917_c0_seq3,339,44.5428,0.56044444,0,0,,1.00E-43,Q5T7B8,Kinesin-like protein KIF24,Kinesin-like protein KIF24,GO:0005524; GO:0005814; GO:0042384; GO:0005871; GO:0005874; GO:0007019; GO:0003777; GO:0007018,ATP binding; centriole; cilium assembly; kinesin complex; microtubule; microtubule depolymerization; microtubule motor activity; microtubule-based movement,PF00225;PF00536;,,,,,,,,,KIF24_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019] comp143919_c1_seq1,1373,45.2294,0.34072255,64,212,,6.00E-45,D3Z9Z9,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12),GO:0005524; GO:0043044; GO:0003677; GO:0000729; GO:0051304; GO:0004386; GO:0000792; GO:0070932; GO:0070933; GO:0005634; GO:0035861,ATP binding; ATP-dependent chromatin remodeling; DNA binding; DNA double-strand break processing; chromosome separation; helicase activity; heterochromatin; histone H3 deacetylation; histone H4 deacetylation; nucleus; site of double-strand break,PF00271;PF00176;,,,,,,,,,SMRCD_RAT,Rattus norvegicus (Rat),ATP-dependent chromatin remodeling [GO:0043044]; chromosome separation [GO:0051304]; DNA double-strand break processing [GO:0000729]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; regulation of DNA recombination [GO:0000018] comp143919_c2_seq1,3403,36.6441,0.46974956,11,38,,2.00E-94,O74842,ATP-dependent helicase fft2 (EC 3.6.4.12) (Fun thirty-related protein 2),ATP-dependent helicase fft2 (EC 3.6.4.12) (Fun thirty-related protein 2),GO:0005524; GO:0004003; GO:0003677; GO:0006338; GO:0005829; GO:0000790,ATP binding; ATP-dependent DNA helicase activity; DNA binding; chromatin remodeling; cytosol; nuclear chromatin,PF00271;PF00176;,,,,,,,,,FFT2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),heterochromatin assembly involved in chromatin silencing [GO:0070869] comp143919_c2_seq2,3413,36.5954,0.46977183,17,178,,2.00E-158,E1B7X9,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12),GO:0005524; GO:0043044; GO:0003677; GO:0000729; GO:0051304; GO:0004386; GO:0000792; GO:0070932; GO:0070933; GO:0005634; GO:0035861,ATP binding; ATP-dependent chromatin remodeling; DNA binding; DNA double-strand break processing; chromosome separation; helicase activity; heterochromatin; histone H3 deacetylation; histone H4 deacetylation; nucleus; site of double-strand break,PF00271;PF00176;,2.00E-83,CHOYP_LOC100373244.1.1,,,,,,,SMRCD_BOVIN,Bos taurus (Bovine),ATP-dependent chromatin remodeling [GO:0043044]; chromosome separation [GO:0051304]; DNA double-strand break processing [GO:0000729]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; regulation of DNA recombination [GO:0000018] comp143920_c0_seq1,2401,42.7322,0.44460048,266,1258,,0,Q56A55,"ATP-binding cassette sub-family B member 8, mitochondrial","ATP-binding cassette sub-family B member 8, mitochondrial",GO:0005524; GO:0042626; GO:0016021; GO:0005743,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrial inner membrane",PF00664;PF00005;,1.00E-128,CHOYP_LOC101062797.1.1,,,,,,,ABCB8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),transmembrane transport [GO:0055085] comp143921_c1_seq2,2862,39.5178,0.3664875,261,2270,,0,P13676,Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase),Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase),GO:0005737; GO:0006508; GO:0004252,cytoplasm; proteolysis; serine-type endopeptidase activity,PF00326;,1.00E-21,CHOYP_LOC100491896.1.1,7.00E-15,ruditapes_c20505,,,,,ACPH_RAT,Rattus norvegicus (Rat), comp143922_c0_seq1,2835,40.0353,0.42484775,809,1839,,1.00E-101,Q5E9J9,STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein),STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein),GO:0005524; GO:0032147; GO:0007049; GO:0005737; GO:0005634; GO:0006611; GO:0030295; GO:0004672,ATP binding; activation of protein kinase activity; cell cycle; cytoplasm; nucleus; protein export from nucleus; protein kinase activator activity; protein kinase activity,PF00069;,3.00E-35,CHOYP_STRAA.1.1,,,,,,,STRAA_BOVIN,Bos taurus (Bovine),activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; protein export from nucleus [GO:0006611] comp143925_c0_seq2,699,49.2132,0.73439977,0,0,,5.00E-30,Q8CI96,CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),CAP-Gly domain-containing linker protein 4 (Restin-like protein 2),,,PF12796;PF01302;,,,,,,,,,CLIP4_MOUSE,Mus musculus (Mouse), comp143925_c1_seq1,3868,39.5295,0.48717396,598,398,,2.00E-37,Q922J3,CAP-Gly domain-containing linker protein 1 (Restin),CAP-Gly domain-containing linker protein 1 (Restin),GO:0005813; GO:0005881; GO:0030659; GO:0044354; GO:0008017; GO:0001578; GO:0035371; GO:0003676; GO:0031116; GO:0001726; GO:0006810; GO:0008270,centrosome; cytoplasmic microtubule; cytoplasmic vesicle membrane; macropinosome; microtubule binding; microtubule bundle formation; microtubule plus end; nucleic acid binding; positive regulation of microtubule polymerization; ruffle; transport; zinc ion binding,PF01302;PF16641;,4.00E-35,CHOYP_LOC100369031.1.1,,,,,,,CLIP1_MOUSE,Mus musculus (Mouse),microtubule bundle formation [GO:0001578]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861] comp143925_c1_seq2,800,49.375,0.78214738,29,8,,2.00E-48,Q9UDT6,CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein),CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein),GO:0005881; GO:0005875,cytoplasmic microtubule; microtubule associated complex,PF01302;,,,,,,,,,CLIP2_HUMAN,Homo sapiens (Human), comp143927_c0_seq2,1108,37.9061,0.50367922,3,71,,2.00E-53,Q9CRD2,ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35),ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35),GO:0072546; GO:0005739; GO:0005634,ER membrane protein complex; mitochondrion; nucleus,,7.00E-38,CHOYP_EMC2.2.2,,,,,,,EMC2_MOUSE,Mus musculus (Mouse), comp143928_c0_seq2,3273,47.4488,0.66160132,0,6,,1.00E-67,P10493,Nidogen-1 (NID-1) (Entactin),Nidogen-1 (NID-1) (Entactin),GO:0005605; GO:0005509; GO:0071944; GO:0007160; GO:0005518; GO:0032836; GO:0043237; GO:0010811,basal lamina; calcium ion binding; cell periphery; cell-matrix adhesion; collagen binding; glomerular basement membrane development; laminin-1 binding; positive regulation of cell-substrate adhesion,PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID1_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; positive regulation of cell-substrate adhesion [GO:0010811] comp143928_c0_seq3,3246,47.443,0.65621244,7,12,,2.00E-67,P10493,Nidogen-1 (NID-1) (Entactin),Nidogen-1 (NID-1) (Entactin),GO:0005605; GO:0005509; GO:0071944; GO:0007160; GO:0005518; GO:0032836; GO:0043237; GO:0010811,basal lamina; calcium ion binding; cell periphery; cell-matrix adhesion; collagen binding; glomerular basement membrane development; laminin-1 binding; positive regulation of cell-substrate adhesion,PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;,5.00E-20,CHOYP_LOC661043.1.1,,,,,,,NID1_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; positive regulation of cell-substrate adhesion [GO:0010811] comp143928_c4_seq1,2195,48.4282,0.3284967,124,102,,3.00E-95,Q6P4R8,Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) (INO80 complex subunit G),Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) (INO80 complex subunit G),GO:0003677; GO:0006310; GO:0006281; GO:0031011; GO:0006954; GO:0006355; GO:0006366,"DNA binding; DNA recombination; DNA repair; Ino80 complex; inflammatory response; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF14465;,2.00E-79,CHOYP_NFRKB.1.1,,,,,,,NFRKB_HUMAN,Homo sapiens (Human),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp143930_c1_seq1,3957,44.8319,0.43270691,12,0,,3.00E-47,Q9UBL0,cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein),cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein),GO:0034605; GO:0005737; GO:0003676,cellular response to heat; cytoplasm; nucleic acid binding,PF01424;PF12752;,6.00E-39,CHOYP_R3HDM1.1.1,,,,,,,ARP21_HUMAN,Homo sapiens (Human),cellular response to heat [GO:0034605] comp143930_c1_seq4,3877,44.8543,0.44114234,0,0,,3.00E-47,Q9UBL0,cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein),cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein),GO:0034605; GO:0005737; GO:0003676,cellular response to heat; cytoplasm; nucleic acid binding,PF01424;PF12752;,7.00E-38,CHOYP_R3HDM1.1.1,,,,,,,ARP21_HUMAN,Homo sapiens (Human),cellular response to heat [GO:0034605] comp143930_c1_seq6,4145,44.4391,0.46433959,0,0,,3.00E-47,Q9UBL0,cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein),cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein),GO:0034605; GO:0005737; GO:0003676,cellular response to heat; cytoplasm; nucleic acid binding,PF01424;PF12752;,8.00E-38,CHOYP_R3HDM1.1.1,,,,,,,ARP21_HUMAN,Homo sapiens (Human),cellular response to heat [GO:0034605] comp143933_c0_seq1,3063,32.9416,0.49387497,107,22,,2.00E-59,Q568D2,Uncharacterized protein C15orf26 homolog,Cilia- and flagella-associated protein 161,,,,,,,,,,,,CO026_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium morphogenesis [GO:0060271] comp143933_c0_seq2,2959,32.9503,0.47365191,19,0,,1.00E-59,Q568D2,Uncharacterized protein C15orf26 homolog,Cilia- and flagella-associated protein 161,,,,4.00E-71,CHOYP_LOC100370551.1.1,,,,,,,CO026_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium morphogenesis [GO:0060271] comp143934_c0_seq2,2241,38.8666,0.38039498,9,36,,2.00E-115,A0JM49,E3 ubiquitin-protein ligase listerin (EC 6.3.2.-) (RING finger protein 160) (Zfp-294),E3 ubiquitin-protein ligase listerin (EC 6.3.2.-) (RING finger protein 160) (Zfp-294),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,PF13639;,2.00E-86,CHOYP_LTN1.1.2,,,,,,,LTN1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination [GO:0016567] comp143934_c0_seq3,2242,38.9384,0.36737084,16,72,,2.00E-43,Q65XX2,E3 ubiquitin-protein ligase listerin (EC 6.3.2.-),E3 ubiquitin-protein ligase listerin (EC 6.3.2.-),GO:0016874; GO:0016567; GO:0008270,ligase activity; protein ubiquitination; zinc ion binding,PF13639;,,,,,,,,,LTN1_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567] comp143935_c0_seq2,4027,45.4184,0.53567042,0,3,,0,Q9ULI0,ATPase family AAA domain-containing protein 2B,ATPase family AAA domain-containing protein 2B,GO:0005524; GO:0070577; GO:0017111,ATP binding; histone acetyl-lysine binding; nucleoside-triphosphatase activity,PF00004;PF00439;,,,,,,,,,ATD2B_HUMAN,Homo sapiens (Human),negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp143935_c0_seq3,4004,45.4296,0.53839254,0,2,,8.00E-73,O28972,Cell division cycle protein 48 homolog AF_1297,Cell division cycle protein 48 homolog AF_1297,GO:0005524; GO:0017111,ATP binding; nucleoside-triphosphatase activity,PF00004;PF02933;PF02359;PF09336;,1.00E-141,CHOYP_ATD2B.1.1,,,,,,,Y1297_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126), comp143935_c0_seq4,4055,45.3761,0.53302965,5,0,,0,Q9ULI0,ATPase family AAA domain-containing protein 2B,ATPase family AAA domain-containing protein 2B,GO:0005524; GO:0070577; GO:0017111,ATP binding; histone acetyl-lysine binding; nucleoside-triphosphatase activity,PF00004;PF00439;,,,,,,,,,ATD2B_HUMAN,Homo sapiens (Human),negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp143935_c0_seq5,1096,45.8942,0.55535563,0,0,,2.00E-143,P54816,Tat-binding homolog 7 (Lin-48 expression abnormal protein 1),Tat-binding homolog 7 (Lin-48 expression abnormal protein 1),GO:0005524; GO:0017111; GO:0031445; GO:0006351,"ATP binding; nucleoside-triphosphatase activity; regulation of heterochromatin assembly; transcription, DNA-dependent",PF00004;PF00439;,1.00E-135,CHOYP_ATD2B.1.1,,,,,,,TBP7_CAEEL,Caenorhabditis elegans,"negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heterochromatin assembly [GO:0031445]; transcription, DNA-templated [GO:0006351]" comp143935_c0_seq6,4034,45.3892,0.53060374,3,0,,4.00E-38,O50202,Proteasome-associated ATPase (AAA ATPase forming ring-shaped complexes) (ARC) (Proteasomal ATPase),Proteasome-associated ATPase (AAA ATPase forming ring-shaped complexes) (ARC) (Proteasomal ATPase),GO:0005524; GO:0016887; GO:0043273; GO:0019941; GO:0010498; GO:0022623; GO:0043335,ATP binding; ATPase activity; CTPase activity; modification-dependent protein catabolic process; proteasomal protein catabolic process; proteasome-activating nucleotidase complex; protein unfolding,PF00004;PF16450;,,,,,,,,,ARC_RHOER,Rhodococcus erythropolis (Arthrobacter picolinophilus),modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]; protein unfolding [GO:0043335] comp143939_c0_seq1,5252,44.6877,0.48545452,26,0,,4.00E-95,Q6ZUG5,Uncharacterized protein FLJ43738,Uncharacterized protein FLJ43738,,,,,,,,,,,,YC006_HUMAN,Homo sapiens (Human), comp143939_c0_seq2,5224,44.7741,0.48626023,23,0,,,,,,,,,3.00E-69,CHOYP_LOC100373146.2.2,,,,,,,,, comp143939_c0_seq3,5241,44.4572,0.47991756,243,0,male,4.00E-95,Q6ZUG5,Uncharacterized protein FLJ43738,Uncharacterized protein FLJ43738,,,,3.00E-69,CHOYP_LOC100373146.2.2,5.00E-20,ruditapes_c21209,,,,,YC006_HUMAN,Homo sapiens (Human), comp143939_c0_seq4,5242,44.525,0.47839951,0,0,,4.00E-95,Q6ZUG5,Uncharacterized protein FLJ43738,Uncharacterized protein FLJ43738,,,,,,,,,,,,YC006_HUMAN,Homo sapiens (Human), comp143939_c0_seq5,5191,44.8661,0.47953021,71,0,,2.00E-19,Q9ULG3,Uncharacterized protein KIAA1257,Uncharacterized protein KIAA1257,,,PF15084;,5.00E-22,CHOYP_LOC100373146.1.2,,,,,,,K1257_HUMAN,Homo sapiens (Human), comp143939_c0_seq6,4949,45.2213,0.48358542,1,0,,2.00E-95,Q6ZUG5,Uncharacterized protein FLJ43738,Uncharacterized protein FLJ43738,,,,3.00E-69,CHOYP_LOC100373146.2.2,,,,,,,YC006_HUMAN,Homo sapiens (Human), comp143940_c1_seq1,2184,42.4908,0.67618209,102,277,,0,Q7TPD0,Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A),Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A),GO:0006281; GO:0070876; GO:0032039; GO:0007093; GO:0010212; GO:0016180,DNA repair; SOSS complex; integrator complex; mitotic cell cycle checkpoint; response to ionizing radiation; snRNA processing,PF10189;,7.00E-130,CHOYP_ISCW_ISCW021591.1.1,,,,,,,INT3_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]; snRNA processing [GO:0016180] comp143942_c0_seq2,7138,38.1339,0.45490074,372,1203,,2.00E-06,Q9H2P0,Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein),Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein),GO:0003682; GO:0005615; GO:0046872; GO:0043524; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"chromatin binding; extracellular space; metal ion binding; negative regulation of neuron apoptotic process; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;,,,,,,,,,ADNP_HUMAN,Homo sapiens (Human),"activation of protein kinase activity [GO:0032147]; cellular response to extracellular stimulus [GO:0031668]; estrous cycle [GO:0044849]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of synaptic transmission [GO:0050805]; nitric oxide homeostasis [GO:0033484]; positive regulation of axon extension [GO:0045773]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of synapse assembly [GO:0051965]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of transcription, DNA-templated [GO:0006355]; response to carbohydrate [GO:0009743]; response to inorganic substance [GO:0010035]; short-term memory [GO:0007614]; transcription, DNA-templated [GO:0006351]" comp143943_c0_seq1,4610,29.9132,0.5604824,195,1198,,4.00E-08,Q54BW4,Circularly permutated Ras protein 2 (DdiCPRas2),Circularly permutated Ras protein 2 (DdiCPRas2),GO:0005525; GO:0003924; GO:0004866; GO:0016020; GO:0010951; GO:0007165,GTP binding; GTPase activity; endopeptidase inhibitor activity; membrane; negative regulation of endopeptidase activity; signal transduction,PF00207;PF07703;PF00071;,,,,,,,,,CPAS2_DICDI,Dictyostelium discoideum (Slime mold),signal transduction [GO:0007165] comp143943_c0_seq2,4594,29.865,0.55433483,145,929,,2.00E-123,Q05974,Ras-related protein Rab-1A,Ras-related protein Rab-1A,GO:0005525; GO:0005794; GO:0005783; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; endoplasmic reticulum; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00071;,6.00E-154,CHOYP_RAB1A.1.3,0,ruditapes_c7176,,,,,RAB1A_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp143944_c0_seq4,3608,37.5,0.94653613,0,0,,2.00E-06,Q8IWR1,Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1),Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1),GO:0005783; GO:0016021; GO:0043124; GO:0004842; GO:0008270,endoplasmic reticulum; integral to membrane; negative regulation of I-kappaB kinase/NF-kappaB cascade; ubiquitin-protein ligase activity; zinc ion binding,PF00643;PF13445;,,,,,,,,,TRI59_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124] comp143944_c0_seq9,3958,36.9631,0.90264484,6,55,,3.00E-06,Q8IWR1,Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1),Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1),GO:0005783; GO:0016021; GO:0043124; GO:0004842; GO:0008270,endoplasmic reticulum; integral to membrane; negative regulation of I-kappaB kinase/NF-kappaB cascade; ubiquitin-protein ligase activity; zinc ion binding,PF00643;PF13445;,,,,,,,,,TRI59_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124] comp143945_c0_seq1,1005,35.9204,0.49434938,0,0,,1.00E-13,O43299,AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5),AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5),GO:0044599; GO:0030119; GO:0008219; GO:0000724; GO:0016197; GO:0005730; GO:0015031,AP-5 adaptor complex; AP-type membrane coat adaptor complex; cell death; double-strand break repair via homologous recombination; endosomal transport; nucleolus; protein transport,PF14764;,4.00E-15,CHOYP_AP5Z1.1.1,,,,,,,AP5Z1_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031] comp143945_c0_seq10,2109,32.1954,0.68248988,0,0,,2.00E-46,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,1.00E-12,CHOYP_RTJK.3.3,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp143945_c0_seq15,2183,31.7911,0.69717757,0,0,,4.00E-13,P16425,Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,Y2R2_DROME,Drosophila melanogaster (Fruit fly), comp143945_c0_seq2,877,34.3216,0.50419714,0,0,,,,,,,,,5.00E-13,CHOYP_RTJK.3.3,,,,,,,,, comp143945_c0_seq20,845,31.9527,0.7433697,0,0,,1.00E-09,Q03270,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO12_NASVI,Nasonia vitripennis (Parasitic wasp), comp143945_c0_seq21,1092,36.2637,0.47439276,0,0,,2.00E-13,O43299,AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5),AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5),GO:0044599; GO:0030119; GO:0008219; GO:0000724; GO:0016197; GO:0005730; GO:0015031,AP-5 adaptor complex; AP-type membrane coat adaptor complex; cell death; double-strand break repair via homologous recombination; endosomal transport; nucleolus; protein transport,PF14764;,4.00E-15,CHOYP_AP5Z1.1.1,,,,,,,AP5Z1_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031] comp143945_c0_seq26,2389,32.3148,0.74946159,0,0,,2.00E-45,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp143945_c0_seq3,839,33.1347,0.6957612,0,0,,3.00E-07,Q03270,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO12_NASVI,Nasonia vitripennis (Parasitic wasp), comp143945_c0_seq5,2372,32.715,0.76516005,0,0,,,,,,,,,,,9.00E-13,ruditapes_c29825,,,,,,, comp143945_c0_seq6,2177,32.2003,0.6448558,0,0,,5.00E-13,P16425,Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,Y2R2_DROME,Drosophila melanogaster (Fruit fly), comp143945_c0_seq7,945,34.2857,0.50466848,0,0,,7.00E-07,Q05118,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00078;,5.00E-13,CHOYP_RTJK.3.3,,,,,,,PO23_POPJA,Popillia japonica (Japanese beetle), comp143945_c0_seq8,2383,32.7319,0.73117145,0,0,,6.00E-46,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,1.00E-12,CHOYP_RTJK.3.3,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp143945_c0_seq9,1160,36.1207,0.47616696,0,0,,2.00E-13,O43299,AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5),AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5),GO:0044599; GO:0030119; GO:0008219; GO:0000724; GO:0016197; GO:0005730; GO:0015031,AP-5 adaptor complex; AP-type membrane coat adaptor complex; cell death; double-strand break repair via homologous recombination; endosomal transport; nucleolus; protein transport,PF14764;,5.00E-15,CHOYP_AP5Z1.1.1,2.00E-23,ruditapes2_c2422,,,,,AP5Z1_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031] comp143946_c1_seq2,2993,32.4424,0.39652245,64,394,,,,,,,,,,,3.00E-13,ruditapes2_c1070,,,,,,, comp143947_c0_seq3,1627,37.7382,0.82586999,21,72,,2.00E-07,P38659,Protein disulfide-isomerase A4 (EC 5.3.4.1) (Calcium-binding protein 2) (CaBP2) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72),Protein disulfide-isomerase A4 (EC 5.3.4.1) (Calcium-binding protein 2) (CaBP2) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72),GO:0045454; GO:0005788; GO:0006662; GO:0042470; GO:0003756; GO:0015035; GO:0005790,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; melanosome; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; smooth endoplasmic reticulum,PF00085;,,,,,,,,,PDIA4_RAT,Rattus norvegicus (Rat),cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; positive regulation of protein folding [GO:1903334]; response to endoplasmic reticulum stress [GO:0034976] comp143947_c0_seq4,1722,36.7596,0.86520336,19,57,,5.00E-24,Q4N4N8,Thioredoxin domain-containing protein (Membrane protein 23) (mp23),Thioredoxin domain-containing protein (Membrane protein 23) (mp23),GO:0045454; GO:0005789; GO:0006662; GO:0016021; GO:0015035,cell redox homeostasis; endoplasmic reticulum membrane; glycerol ether metabolic process; integral to membrane; protein disulfide oxidoreductase activity,PF00085;,,,,,,,,,TXND_THEPA,Theileria parva (East coast fever infection agent),cell redox homeostasis [GO:0045454] comp143948_c0_seq10,1203,36.409,0.67921737,0,0,,9.00E-64,Q96PE7,"Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase)","Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase)",GO:0046491; GO:0006635; GO:0004493; GO:0005759; GO:0019626,L-methylmalonyl-CoA metabolic process; fatty acid beta-oxidation; methylmalonyl-CoA epimerase activity; mitochondrial matrix; short-chain fatty acid catabolic process,,3.00E-75,CHOYP_MCEE.1.1,,,,,,,MCEE_HUMAN,Homo sapiens (Human),L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626] comp143948_c0_seq12,1622,34.7102,0.80120787,0,0,,2.00E-62,Q96PE7,"Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase)","Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase)",GO:0046491; GO:0006635; GO:0004493; GO:0005759; GO:0019626,L-methylmalonyl-CoA metabolic process; fatty acid beta-oxidation; methylmalonyl-CoA epimerase activity; mitochondrial matrix; short-chain fatty acid catabolic process,,1.00E-69,CHOYP_LOC100232142.1.1,,,,,,,MCEE_HUMAN,Homo sapiens (Human),L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626] comp143948_c0_seq5,1206,37.3134,0.73923316,232,344,,,,,,,,,3.00E-75,CHOYP_MCEE.1.1,,,,,,,,, comp143948_c0_seq7,1417,35.1447,0.68745994,0,0,,,,,,,,,8.00E-70,CHOYP_LOC100232142.1.1,,,,,,,,, comp143949_c1_seq2,2903,44.1957,0.5223657,11,8,,5.00E-23,O02626,"MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3)","MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3)",GO:0017112; GO:0006915; GO:0005623; GO:0005737; GO:0030421; GO:0007618; GO:0016020; GO:0018991; GO:0014057; GO:0007268,"Rab guanyl-nucleotide exchange factor activity; apoptotic process; cell; cytoplasm; defecation; mating; membrane; oviposition; positive regulation of acetylcholine secretion, neurotransmission; synaptic transmission",PF02141;PF03456;,0,CHOYP_DENND4A.1.1,,,,,,,MADD_CAEEL,Caenorhabditis elegans,"apoptotic process [GO:0006915]; chemical synaptic transmission [GO:0007268]; defecation [GO:0030421]; mating [GO:0007618]; oviposition [GO:0018991]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]" comp143949_c1_seq4,2863,44.4289,0.50989213,5,0,,0,Q7Z401,C-myc promoter-binding protein (DENN domain-containing protein 4A),C-myc promoter-binding protein (DENN domain-containing protein 4A),GO:0003677; GO:0017112; GO:0005634; GO:0006355; GO:0006351,"DNA binding; Rab guanyl-nucleotide exchange factor activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03455;PF02141;PF03456;,0,CHOYP_DENND4A.1.1,,,,,,,MYCPP_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143949_c1_seq5,371,41.5094,0.50500961,13,30,,6.00E-09,Q3U1Y4,DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4),DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4),GO:0005794; GO:0017112,Golgi apparatus; Rab guanyl-nucleotide exchange factor activity,PF03455;PF02141;PF03456;,,,,,,,,,DEN4B_MOUSE,Mus musculus (Mouse),regulation of Rab protein signal transduction [GO:0032483] comp143949_c1_seq8,804,42.9104,0.60001448,0,0,,3.00E-20,Q7Z401,C-myc promoter-binding protein (DENN domain-containing protein 4A),C-myc promoter-binding protein (DENN domain-containing protein 4A),GO:0003677; GO:0017112; GO:0005634; GO:0006355; GO:0006351,"DNA binding; Rab guanyl-nucleotide exchange factor activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03455;PF02141;PF03456;,,,,,,,,,MYCPP_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143950_c0_seq1,1875,44.8533,0.61627321,0,0,,3.00E-147,O95239,Chromosome-associated kinesin KIF4A (Chromokinesin-A),Chromosome-associated kinesin KIF4A (Chromokinesin-A),GO:0005524; GO:0003677; GO:0008089; GO:0019886; GO:0007411; GO:0007596; GO:0005694; GO:0005829; GO:0005871; GO:0003777; GO:0030496; GO:0016363; GO:0005634; GO:0006996; GO:0005876,ATP binding; DNA binding; anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; blood coagulation; chromosome; cytosol; kinesin complex; microtubule motor activity; midbody; nuclear matrix; nucleus; organelle organization; spindle microtubule,PF00225;,2.00E-79,CHOYP_KIF4A.1.1,,,,,,,KIF4A_HUMAN,Homo sapiens (Human),"anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp143950_c0_seq2,5041,41.5195,0.5782966,108,144,,0,Q90640,Chromosome-associated kinesin KIF4 (Chromokinesin),Chromosome-associated kinesin KIF4 (Chromokinesin),GO:0005524; GO:0003677; GO:0005694; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005634,ATP binding; DNA binding; chromosome; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; nucleus,PF00225;,8.00E-20,CHOYP_KIF21A.1.1,,,,,,,KIF4_CHICK,Gallus gallus (Chicken),microtubule-based movement [GO:0007018] comp143950_c0_seq3,2825,43.6814,0.64233292,13,7,,,,,,,,,4.00E-27,CHOYP_KIF4A.1.1,,,,,,,,, comp143950_c0_seq5,2118,43.4372,0.60924665,10,0,,1.00E-66,O95239,Chromosome-associated kinesin KIF4A (Chromokinesin-A),Chromosome-associated kinesin KIF4A (Chromokinesin-A),GO:0005524; GO:0003677; GO:0008089; GO:0019886; GO:0007411; GO:0007596; GO:0005694; GO:0005829; GO:0005871; GO:0003777; GO:0030496; GO:0016363; GO:0005634; GO:0006996; GO:0005876,ATP binding; DNA binding; anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; axon guidance; blood coagulation; chromosome; cytosol; kinesin complex; microtubule motor activity; midbody; nuclear matrix; nucleus; organelle organization; spindle microtubule,PF00225;,,,,,,,,,KIF4A_HUMAN,Homo sapiens (Human),"anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp143950_c0_seq6,848,43.2783,0.56171135,0,13,,1.00E-43,Q7M6Z4,Kinesin-like protein KIF27,Kinesin-like protein KIF27,GO:0005524; GO:0005929; GO:0042384; GO:0005737; GO:0003351; GO:0005871; GO:0005874; GO:0003777; GO:0021591,ATP binding; cilium; cilium assembly; cytoplasm; epithelial cilium movement; kinesin complex; microtubule; microtubule motor activity; ventricular system development,PF00225;,,,,,,,,,KIF27_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; ventricular system development [GO:0021591] comp143951_c0_seq1,3356,38.9452,0.3832739,21,5,,2.00E-73,Q8BQM4,HEAT repeat-containing protein 3,HEAT repeat-containing protein 3,,,,,,,,,,,,HEAT3_MOUSE,Mus musculus (Mouse), comp143951_c0_seq4,3366,38.9186,0.39037685,2,18,,2.00E-73,Q8BQM4,HEAT repeat-containing protein 3,HEAT repeat-containing protein 3,,,,,,,,,,,,HEAT3_MOUSE,Mus musculus (Mouse), comp143952_c1_seq1,3051,28.9741,0.7967935,5,76,,5.00E-11,Q03278,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO21_NASVI,Nasonia vitripennis (Parasitic wasp), comp143952_c1_seq5,3114,33.3654,0.67207548,6,18,,9.00E-09,B7MPB6,"2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase (EC 3.7.1.14) (2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase)","2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase (EC 3.7.1.14) (2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase)",GO:0052823; GO:0018771; GO:0019380; GO:0005737,"2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity; 3-phenylpropionate catabolic process; cytoplasm",PF12697;,3.00E-98,CHOYP_BPHL.1.1,5.00E-17,ruditapes_c21640,,,,,MHPC_ECO81,Escherichia coli O81 (strain ED1a),3-phenylpropionate catabolic process [GO:0019380] comp143952_c1_seq7,3096,33.4302,0.68467385,8,53,,5.00E-88,Q86WA6,Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA),Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA),GO:0006520; GO:0016787; GO:0005739; GO:0009636,cellular amino acid metabolic process; hydrolase activity; mitochondrion; response to toxic substance,PF00561;,3.00E-98,CHOYP_BPHL.1.1,,,,,,,BPHL_HUMAN,Homo sapiens (Human),cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805] comp143953_c0_seq1,2702,41.3768,0.43628164,0,0,,2.00E-106,O13067,Condensin complex subunit 2 (Barren homolog) (Chromosome assembly protein xCAP-H) (Chromosome-associated protein H) (Non-SMC condensin I complex subunit H),Condensin complex subunit 2 (Barren homolog) (Chromosome assembly protein xCAP-H) (Chromosome-associated protein H) (Non-SMC condensin I complex subunit H),GO:0051301; GO:0005694; GO:0030261; GO:0005829; GO:0007067; GO:0005634,cell division; chromosome; chromosome condensation; cytosol; mitosis; nucleus,PF05786;,5.00E-89,CHOYP_BRAFLDRAFT_124950.1.1,,,,,,,CND2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp143956_c0_seq1,2378,41.2952,0.5682367,77,79,,2.00E-67,Q1RMI3,GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2),GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2),GO:0005634; GO:0045944; GO:0044212; GO:0006351,"nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; transcription, DNA-dependent",PF12796;,1.00E-77,CHOYP_LOC100369954.1.1,3.00E-12,ruditapes_c9024,,,,,GABP1_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143956_c0_seq2,2453,40.8887,0.58041637,72,66,,7.00E-13,Q7T163,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0016021; GO:0005770; GO:0007399,integral to membrane; late endosome; nervous system development,PF00023;PF12796;PF07693;,1.00E-76,CHOYP_LOC100369954.1.1,,,,,,,KDIS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859] comp143959_c0_seq1,838,42.1241,0.45980078,7,0,,,,,,,,,2.00E-61,CHOYP_PHUM_PHUM359090.1.1,,,,,,,,, comp143959_c0_seq2,1112,37.8597,0.43388863,15,11,,6.00E-16,Q8JGT4,Netrin receptor UNC5B (Protein Xunc-5) (Protein unc-5 homolog),Netrin receptor UNC5B-a (Protein Xunc-5) (Protein unc-5 homolog-a),GO:0016021; GO:0007275; GO:0007165,integral to membrane; multicellular organismal development; signal transduction,PF00531;PF07679;PF00090;PF00791;,,,,,,,,,UNC5B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; signal transduction [GO:0007165] comp143959_c1_seq1,5026,43.9713,0.74120252,4,0,,4.00E-96,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,2.00E-121,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143959_c1_seq10,4840,43.5537,0.76260861,0,0,,3.00E-96,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,,,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143959_c1_seq11,4176,46.432,0.79103288,0,0,,1.00E-15,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,1.00E-118,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp143959_c1_seq12,4118,45.6289,0.80753727,0,0,,1.00E-51,Q15700,Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),GO:0030054; GO:0004385; GO:0044224; GO:0010923; GO:0005886; GO:0014069; GO:0045211; GO:0019233; GO:0007268,cell junction; guanylate kinase activity; juxtaparanode region of axon; negative regulation of phosphatase activity; plasma membrane; postsynaptic density; postsynaptic membrane; sensory perception of pain; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,1.00E-48,CHOYP_ISCW_ISCW019818.1.1,,,,,,,DLG2_HUMAN,Homo sapiens (Human),chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233] comp143959_c1_seq13,4846,43.4998,0.76356135,0,0,,3.00E-96,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,,,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143959_c1_seq14,4290,46.014,0.78850744,0,0,,1.00E-51,Q15700,Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),GO:0030054; GO:0004385; GO:0044224; GO:0010923; GO:0005886; GO:0014069; GO:0045211; GO:0019233; GO:0007268,cell junction; guanylate kinase activity; juxtaparanode region of axon; negative regulation of phosphatase activity; plasma membrane; postsynaptic density; postsynaptic membrane; sensory perception of pain; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,1.00E-116,CHOYP_PHUM_PHUM359090.1.1,,,,,,,DLG2_HUMAN,Homo sapiens (Human),chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233] comp143959_c1_seq15,4004,46.0539,0.81045886,0,0,,1.00E-15,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,9.00E-119,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp143959_c1_seq16,1686,47.5682,0.78794493,3,0,,5.00E-17,Q9BXL6,Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2),Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2),GO:0007250; GO:0016235; GO:0006915; GO:0005737; GO:0043066; GO:0005886; GO:0051092; GO:0033209,activation of NF-kappaB-inducing kinase activity; aggresome; apoptotic process; cytoplasm; negative regulation of apoptotic process; plasma membrane; positive regulation of NF-kappaB transcription factor activity; tumor necrosis factor-mediated signaling pathway,PF00619;PF00625;,4.00E-49,CHOYP_ISCW_ISCW019818.1.1,,,,,,,CAR14_HUMAN,Homo sapiens (Human),activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein phosphorylation [GO:0001934]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp143959_c1_seq17,4281,45.9472,0.79244651,0,0,,8.00E-97,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,8.00E-120,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143959_c1_seq18,4735,43.9282,0.76189634,0,0,,3.00E-11,Q92796,Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR),Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR),GO:0032281; GO:0007411; GO:0005737; GO:0043198; GO:0001736; GO:0045197; GO:0030426; GO:0004385; GO:0008285; GO:0010923; GO:0043025; GO:0019902; GO:0005886; GO:0045202; GO:0007268; GO:0005923,alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; axon guidance; cytoplasm; dendritic shaft; establishment of planar polarity; establishment or maintenance of epithelial cell apical/basal polarity; growth cone; guanylate kinase activity; negative regulation of cell proliferation; negative regulation of phosphatase activity; neuronal cell body; phosphatase binding; plasma membrane; synapse; synaptic transmission; tight junction,PF00625;PF00595;PF10600;PF00018;,7.00E-109,CHOYP_PHUM_PHUM359090.1.1,,,,,,,DLG3_HUMAN,Homo sapiens (Human),chemical synaptic transmission [GO:0007268]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of cell proliferation [GO:0008285]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp143959_c1_seq19,4741,43.8726,0.76286511,0,0,,1.00E-15,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,1.00E-118,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp143959_c1_seq2,4849,43.6172,0.75898897,0,0,,1.00E-42,Q8TDM6,Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),GO:0008013; GO:0005913; GO:0016337; GO:0005737; GO:0008092; GO:0035556; GO:0008285; GO:0005886; GO:0030159; GO:0042981,beta-catenin binding; cell-cell adherens junction; cell-cell adhesion; cytoplasm; cytoskeletal protein binding; intracellular signal transduction; negative regulation of cell proliferation; plasma membrane; receptor signaling complex scaffold activity; regulation of apoptotic process,PF00625;PF00595;PF04822;,,,,,,,,,DLG5_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186] comp143959_c1_seq20,4855,43.5633,0.75993743,0,0,,2.00E-94,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,2.00E-116,CHOYP_PHUM_PHUM359090.1.1,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143959_c1_seq3,1117,45.3894,0.76563485,0,10,,5.00E-06,Q6QA76,PDZ domain-containing protein 11,PDZ domain-containing protein 11,GO:0016323; GO:0005829; GO:0008022,basolateral plasma membrane; cytosol; protein C-terminus binding,PF00595;,,,,,,,,,PDZ11_PIG,Sus scrofa (Pig),exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361] comp143959_c1_seq4,4091,46.5167,0.78192527,0,0,,2.00E-17,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,2.00E-115,CHOYP_PHUM_PHUM359090.1.1,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp143959_c1_seq5,4461,46.3797,0.76733309,0,0,,1.00E-96,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,9.00E-120,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143959_c1_seq6,2966,46.7633,0.82671683,0,0,,2.00E-43,Q8TDM6,Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG),GO:0008013; GO:0005913; GO:0016337; GO:0005737; GO:0008092; GO:0035556; GO:0008285; GO:0005886; GO:0030159; GO:0042981,beta-catenin binding; cell-cell adherens junction; cell-cell adhesion; cytoplasm; cytoskeletal protein binding; intracellular signal transduction; negative regulation of cell proliferation; plasma membrane; receptor signaling complex scaffold activity; regulation of apoptotic process,PF00625;PF00595;PF04822;,1.00E-116,CHOYP_PHUM_PHUM359090.1.1,,,,,,,DLG5_HUMAN,Homo sapiens (Human),apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186] comp143959_c1_seq7,4289,46.0014,0.78473571,10,5,,2.00E-17,Q28C55,Disks large homolog 1,Disks large homolog 1,GO:0030054; GO:0005789,cell junction; endoplasmic reticulum membrane,PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;,8.00E-120,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,DLG1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120] comp143959_c1_seq8,5020,44.004,0.74101711,0,0,,8.00E-53,Q15700,Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93),GO:0030054; GO:0004385; GO:0044224; GO:0010923; GO:0005886; GO:0014069; GO:0045211; GO:0019233; GO:0007268,cell junction; guanylate kinase activity; juxtaparanode region of axon; negative regulation of phosphatase activity; plasma membrane; postsynaptic density; postsynaptic membrane; sensory perception of pain; synaptic transmission,PF00625;PF10608;PF00595;PF10600;PF07653;,,,,,,,,,DLG2_HUMAN,Homo sapiens (Human),chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233] comp143959_c1_seq9,4109,45.5585,0.8117708,0,0,,5.00E-97,O97758,Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1),GO:0009986; GO:0071277; GO:0031410; GO:0005921; GO:0005886; GO:0005923; GO:0070830,cell surface; cellular response to calcium ion; cytoplasmic vesicle; gap junction; plasma membrane; tight junction; tight junction assembly,PF00625;PF00595;PF07653;PF00791;,8.00E-120,CHOYP_BRAFLDRAFT_93411.1.3,,,,,,,ZO1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277] comp143960_c0_seq1,3556,46.8785,0.46677729,511,342,,0,O15067,Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase),Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase),GO:0006189; GO:0005524; GO:0005829; GO:0006541; GO:0004642; GO:0006144; GO:0042493,'de novo' IMP biosynthetic process; ATP binding; cytosol; glutamine metabolic process; phosphoribosylformylglycinamidine synthase activity; purine nucleobase metabolic process; response to drug,PF02769;,0,CHOYP_BRAFLDRAFT_278091.1.1,,,,,,,PUR4_HUMAN,Homo sapiens (Human),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to drug [GO:0042493]; ribonucleoside monophosphate biosynthetic process [GO:0009156] comp143960_c0_seq3,912,41.7763,0.42925545,1,0,,6.00E-71,Q5SUR0,Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase),Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase),GO:0006189; GO:0005524; GO:0005737; GO:0006541; GO:0004642,'de novo' IMP biosynthetic process; ATP binding; cytoplasm; glutamine metabolic process; phosphoribosylformylglycinamidine synthase activity,PF02769;,,,,,,,,,PUR4_MOUSE,Mus musculus (Mouse),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; response to drug [GO:0042493]; ribonucleoside monophosphate biosynthetic process [GO:0009156] comp143963_c1_seq1,2474,38.9652,0.45978697,23,110,,3.00E-45,Q32N55,"Pentatricopeptide repeat domain-containing protein 3, mitochondrial","Pentatricopeptide repeat domain-containing protein 3, mitochondrial",GO:0032543; GO:0005739; GO:0019843; GO:0006417; GO:0043024,mitochondrial translation; mitochondrion; rRNA binding; regulation of translation; ribosomal small subunit binding,PF13812;,,,,,,,,,PTCD3_XENLA,Xenopus laevis (African clawed frog),mitochondrial translation [GO:0032543]; regulation of translation [GO:0006417] comp143963_c1_seq2,2682,38.9635,0.44114444,0,0,,3.00E-51,Q96EY7,"Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)","Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)",GO:0032543; GO:0005739; GO:0019843; GO:0006417; GO:0043024,mitochondrial translation; mitochondrion; rRNA binding; regulation of translation; ribosomal small subunit binding,PF13041;PF13812;,,,,,,,,,PTCD3_HUMAN,Homo sapiens (Human),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; regulation of translation [GO:0006417] comp143963_c1_seq6,2613,39.3418,0.44455789,0,0,,2.00E-51,Q96EY7,"Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)","Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)",GO:0032543; GO:0005739; GO:0019843; GO:0006417; GO:0043024,mitochondrial translation; mitochondrion; rRNA binding; regulation of translation; ribosomal small subunit binding,PF13041;PF13812;,,,,,,,,,PTCD3_HUMAN,Homo sapiens (Human),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; regulation of translation [GO:0006417] comp143965_c1_seq1,2403,37.6196,0.47748633,0,45,,1.00E-180,Q3ZCJ8,Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],GO:0008234; GO:0005764; GO:0006508; GO:0031638,cysteine-type peptidase activity; lysosome; proteolysis; zymogen activation,PF08773;PF00112;,,,1.00E-16,ruditapes_c27808,,,,,CATC_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638] comp143965_c1_seq2,2390,37.6987,0.47773668,0,58,,0,Q3ZCJ8,Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],GO:0008234; GO:0005764; GO:0006508; GO:0031638,cysteine-type peptidase activity; lysosome; proteolysis; zymogen activation,PF08773;PF00112;,1.00E-82,CHOYP_BRAFLDRAFT_125840.1.1,,,,,,,CATC_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638] comp143965_c1_seq3,2508,37.5997,0.50167238,7,5,,4.00E-175,P53634,Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],GO:0005794; GO:0001913; GO:0007568; GO:0031404; GO:0008234; GO:0005783; GO:0006955; GO:0005764; GO:0006508; GO:0010033; GO:0004252,Golgi apparatus; T cell mediated cytotoxicity; aging; chloride ion binding; cysteine-type peptidase activity; endoplasmic reticulum; immune response; lysosome; proteolysis; response to organic substance; serine-type endopeptidase activity,PF08773;PF00112;,,,,,,,,,CATC_HUMAN,Homo sapiens (Human),aging [GO:0007568]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; immune response [GO:0006955]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to organic substance [GO:0010033]; T cell mediated cytotoxicity [GO:0001913] comp143965_c1_seq4,2495,37.9158,0.49620481,57,125,,1.00E-175,Q5RB02,Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)],GO:0008234; GO:0005764; GO:0006508,cysteine-type peptidase activity; lysosome; proteolysis,PF08773;PF00112;,2.00E-86,CHOYP_BRAFLDRAFT_125840.1.1,,,,,,,CATC_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp143966_c2_seq1,3714,30.2369,0.47782583,8,229,,,,,,,,,,,5.00E-18,ruditapes_c3560,,,,,,, comp143968_c0_seq1,3151,38.3688,0.37453303,384,3408,,0,Q6P1B1,"Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)","Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)",GO:0010815; GO:0005737; GO:0030145; GO:0070006; GO:0006508,bradykinin catabolic process; cytoplasm; manganese ion binding; metalloaminopeptidase activity; proteolysis,PF01321;PF00557;PF16188;,1.00E-96,CHOYP_XPP1.1.2,,,,,,,XPP1_MOUSE,Mus musculus (Mouse),bradykinin catabolic process [GO:0010815]; proteolysis [GO:0006508] comp143969_c0_seq1,4348,48.827,0.70264004,0,0,,6.00E-13,Q6ZCX3,Formin-like protein 6 (OsFH6),Formin-like protein 6 (OsFH6),GO:0005884; GO:0045010; GO:0004721,actin filament; actin nucleation; phosphoprotein phosphatase activity,PF02181;PF10409;,2.00E-89,CHOYP_TENS3.1.4,,,,,,,FH6_ORYSJ,Oryza sativa subsp. japonica (Rice), comp143969_c0_seq10,4339,48.8361,0.70763832,0,0,,2.00E-125,Q9GLM4,Tensin-1,Tensin-1,GO:0009986; GO:0005737; GO:0005856; GO:0005925,cell surface; cytoplasm; cytoskeleton; focal adhesion,PF08416;PF10409;PF00017;,,,,,,,,,TENS1_BOVIN,Bos taurus (Bovine), comp143969_c0_seq12,4057,48.6813,0.69811714,0,0,,5.00E-131,Q04205,Tensin,Tensin,GO:0005912; GO:0009986; GO:0005737; GO:0005856,adherens junction; cell surface; cytoplasm; cytoskeleton,PF08416;PF10409;PF00017;,2.00E-89,CHOYP_TENS3.1.4,,,,,,,TENS_CHICK,Gallus gallus (Chicken), comp143969_c0_seq14,4258,48.8727,0.7086233,0,0,,1.00E-130,Q04205,Tensin,Tensin,GO:0005912; GO:0009986; GO:0005737; GO:0005856,adherens junction; cell surface; cytoplasm; cytoskeleton,PF08416;PF10409;PF00017;,,,,,,,,,TENS_CHICK,Gallus gallus (Chicken), comp143969_c0_seq2,4366,48.809,0.70420011,0,0,,5.00E-33,P97874,Cyclin-G-associated kinase (EC 2.7.11.1),Cyclin-G-associated kinase (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0007049; GO:0030332; GO:0005925; GO:0048471; GO:0004674,ATP binding; Golgi apparatus; cell cycle; cyclin binding; focal adhesion; perinuclear region of cytoplasm; protein serine/threonine kinase activity,PF00226;PF00069;PF10409;,,,,,,,,,GAK_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; receptor-mediated endocytosis [GO:0006898] comp143969_c0_seq3,4321,48.8544,0.70608298,0,0,,2.00E-130,Q04205,Tensin,Tensin,GO:0005912; GO:0009986; GO:0005737; GO:0005856,adherens junction; cell surface; cytoplasm; cytoskeleton,PF08416;PF10409;PF00017;,2.00E-89,CHOYP_TENS3.1.4,,,,,,,TENS_CHICK,Gallus gallus (Chicken), comp143969_c0_seq6,528,51.7045,0.60126866,87,354,,2.00E-41,Q32PJ7,Tensin-4,Tensin-4,GO:0006915; GO:0005737; GO:0005856; GO:0005925,apoptotic process; cytoplasm; cytoskeleton; focal adhesion,PF08416;PF00017;,,,,,,,,,TENS4_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915] comp143969_c0_seq7,4030,48.7097,0.7018241,0,0,,4.00E-131,Q04205,Tensin,Tensin,GO:0005912; GO:0009986; GO:0005737; GO:0005856,adherens junction; cell surface; cytoplasm; cytoskeleton,PF08416;PF10409;PF00017;,2.00E-89,CHOYP_TENS3.1.4,,,,,,,TENS_CHICK,Gallus gallus (Chicken), comp143970_c0_seq1,2356,41.9355,0.4057348,247,1328,,2.00E-102,Q9I9A7,DNA replication factor Cdt1 (XCDT1),DNA replication factor Cdt1 (XCDT1),GO:0003677; GO:0006260; GO:0007049; GO:0005634,DNA binding; DNA replication; cell cycle; nucleus,PF08839;PF16679;,5.00E-31,CHOYP_LOC100376797.1.1,,,,,,,CDT1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; DNA replication [GO:0006260] comp143971_c0_seq1,5438,44.7775,0.53016251,4530,538,,6.00E-96,Q9P1Z9,Coiled-coil domain-containing protein 180,Coiled-coil domain-containing protein 180,GO:0016021,integral to membrane,PF14643;PF14644;,0,CHOYP_LOC100369255.2.3,,,,,,,CI174_HUMAN,Homo sapiens (Human), comp143971_c0_seq2,2556,45.1095,0.41963136,246,13,,8.00E-100,Q9P1Z9,Coiled-coil domain-containing protein 180,Coiled-coil domain-containing protein 180,GO:0016021,integral to membrane,PF14643;PF14644;,,,,,,,,,CI174_HUMAN,Homo sapiens (Human), comp143972_c1_seq1,5559,46.843,0.67237105,240,1522,,3.00E-162,O35889,Afadin (Protein Af-6),Afadin (Protein Af-6),GO:0007155; GO:0005913; GO:0005829; GO:0007165,cell adhesion; cell-cell adherens junction; cytosol; signal transduction,PF01843;PF00498;PF00595;PF00788;,1.00E-150,CHOYP_BRAFLDRAFT_208117.1.3,2.00E-38,ruditapes_c8863,,,,,AFAD_RAT,Rattus norvegicus (Rat),adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; signal transduction [GO:0007165] comp143973_c1_seq2,5855,41.1272,0.55149438,809,2013,,0,P09884,DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180),DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180),GO:0008408; GO:0051539; GO:0003677; GO:0006270; GO:0006269; GO:0003887; GO:0005658; GO:0008283; GO:0003682; GO:0005737; GO:0006303; GO:0006273; GO:0006272; GO:0046872; GO:0000084; GO:0019048; GO:0005635; GO:0016363; GO:0005730; GO:0005654; GO:0001882; GO:0000166; GO:0000083; GO:0000722; GO:0032201; GO:0019985,"3'-5' exonuclease activity; 4 iron, 4 sulfur cluster binding; DNA binding; DNA replication initiation; DNA replication, synthesis of RNA primer; DNA-directed DNA polymerase activity; alpha DNA polymerase:primase complex; cell proliferation; chromatin binding; cytoplasm; double-strand break repair via nonhomologous end joining; lagging strand elongation; leading strand elongation; metal ion binding; mitotic S phase; modulation by virus of host morphology or physiology; nuclear envelope; nuclear matrix; nucleolus; nucleoplasm; nucleoside binding; nucleotide binding; regulation of transcription involved in G1/S transition of mitotic cell cycle; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; translesion synthesis",PF12254;PF00136;PF03104;PF08996;,0,CHOYP_LOC584095.1.1,,,5.00E-109,AM859992.p.cg.6,7,,DPOLA_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via nonhomologous end joining [GO:0006303]; G1/S transition of mitotic cell cycle [GO:0000082]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; telomere maintenance via recombination [GO:0000722]; viral process [GO:0016032]" comp143974_c1_seq1,3458,35.5986,0.4017634,0,0,,6.00E-30,Q96LQ0,Protein phosphatase 1 regulatory subunit 36,Protein phosphatase 1 regulatory subunit 36,GO:0010923; GO:0019902; GO:0004864,negative regulation of phosphatase activity; phosphatase binding; protein phosphatase inhibitor activity,PF14895;,,,,,,,,,PPR36_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923] comp143974_c1_seq2,1564,40.4092,0.39238021,0,0,,3.00E-31,Q96LQ0,Protein phosphatase 1 regulatory subunit 36,Protein phosphatase 1 regulatory subunit 36,GO:0010923; GO:0019902; GO:0004864,negative regulation of phosphatase activity; phosphatase binding; protein phosphatase inhibitor activity,PF14895;,2.00E-58,CHOYP_ISCW_ISCW014880.1.1,,,,,,,PPR36_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923] comp143974_c1_seq3,3429,35.783,0.40102039,0,0,,,,,,,,,5.00E-58,CHOYP_ISCW_ISCW014880.1.1,,,,,,,,, comp143974_c1_seq8,3327,36.3992,0.38133904,32,8,,6.00E-30,Q96LQ0,Protein phosphatase 1 regulatory subunit 36,Protein phosphatase 1 regulatory subunit 36,GO:0010923; GO:0019902; GO:0004864,negative regulation of phosphatase activity; phosphatase binding; protein phosphatase inhibitor activity,PF14895;,5.00E-58,CHOYP_ISCW_ISCW014880.1.1,,,,,,,PPR36_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923] comp143975_c0_seq1,1214,45.0577,0.45600531,76,226,,2.00E-124,Q5ZK69,Proteasomal ATPase-associated factor 1 (WD repeat-containing protein 71),Proteasomal ATPase-associated factor 1 (WD repeat-containing protein 71),GO:0000502,proteasome complex,PF00400;,8.00E-38,CHOYP_BRAFLDRAFT_104267.1.1,,,,,,,PAAF1_CHICK,Gallus gallus (Chicken), comp143978_c0_seq1,1602,42.9463,0.38650803,3,0,,2.00E-18,Q5F478,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44),,,PF00023;PF12796;,,,,,,,,,ANR44_CHICK,Gallus gallus (Chicken), comp143978_c0_seq2,1414,42.8571,0.38068354,0,0,,3.00E-15,Q8WXK3,Ankyrin repeat and SOCS box protein 13 (ASB-13),Ankyrin repeat and SOCS box protein 13 (ASB-13),GO:0035556; GO:0016567,intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,,,,,,,,,ASB13_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp143978_c0_seq3,4775,42.5131,0.40688603,381,317,,2.00E-52,Q9TXQ1,Poly(ADP-ribose) polymerase pme-5 (EC 2.4.2.30) (Poly ADP-ribose metabolism enzyme 5),Tankyrase-like protein (EC 2.4.2.30) (Poly ADP-ribose metabolism enzyme 5) (Poly(ADP-ribose) polymerase pme-5),GO:0006281; GO:0003950; GO:0043069; GO:0005634; GO:0006471,DNA repair; NAD+ ADP-ribosyltransferase activity; negative regulation of programmed cell death; nucleus; protein ADP-ribosylation,PF12796;PF00644;PF02877;PF05406;,,,,,,,,,PME5_CAEEL,Caenorhabditis elegans,cellular response to DNA damage stimulus [GO:0006974]; DNA ligation involved in DNA repair [GO:0051103]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lagging strand elongation [GO:0006273]; negative regulation of programmed cell death [GO:0043069]; protein ADP-ribosylation [GO:0006471]; response to gamma radiation [GO:0010332] comp143978_c1_seq1,737,42.4695,0.37586013,77,162,,,,,,,,,2.00E-24,CHOYP_LOC588883.2.3,,,,,,,,, comp143979_c2_seq3,1701,40.682,0.49829791,261,323,,7.00E-54,Q5VT52,Regulation of nuclear pre-mRNA domain-containing protein 2,Regulation of nuclear pre-mRNA domain-containing protein 2,GO:0016591,"DNA-directed RNA polymerase II, holoenzyme",PF16566;PF04818;,,,,,,,,,RPRD2_HUMAN,Homo sapiens (Human),snRNA transcription from RNA polymerase II promoter [GO:0042795] comp143980_c0_seq1,2296,46.2979,0.68513126,58,0,,2.00E-180,O75122,CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2),CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2),GO:0005794; GO:0007411; GO:0005938; GO:0051301; GO:0000777; GO:0005881; GO:0005829; GO:0007163; GO:0008107; GO:0005828; GO:0034453; GO:0007020; GO:0005815; GO:0031023; GO:0051010; GO:0007067; GO:0000278; GO:0007026; GO:0032587; GO:0005802,Golgi apparatus; axon guidance; cell cortex; cell division; condensed chromosome kinetochore; cytoplasmic microtubule; cytosol; establishment or maintenance of cell polarity; galactoside 2-alpha-L-fucosyltransferase activity; kinetochore microtubule; microtubule anchoring; microtubule nucleation; microtubule organizing center; microtubule organizing center organization; microtubule plus-end binding; mitosis; mitotic cell cycle; negative regulation of microtubule depolymerization; ruffle membrane; trans-Golgi network,PF12348;,5.00E-94,CHOYP_CLAP1.2.6,,,,,,,CLAP2_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; establishment of protein localization to plasma membrane [GO:0090002]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle organization [GO:0007052]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; sister chromatid cohesion [GO:0007062]; vesicle targeting [GO:0006903]" comp143980_c0_seq2,1570,43.5669,0.65895421,154,62,,5.00E-16,P32744,Protein CLASP-2,Protein CLASP-2,GO:0005813; GO:0000777; GO:0000910; GO:0005737; GO:0016482; GO:0000776; GO:0007126; GO:0005874; GO:0051306; GO:0072686; GO:0031134,centrosome; condensed chromosome kinetochore; cytokinesis; cytoplasm; cytoplasmic transport; kinetochore; meiosis; microtubule; mitotic sister chromatid separation; mitotic spindle; sister chromatid biorientation,PF12348;,3.00E-75,CHOYP_CLAP1.3.6,,,,,,,CLAS2_CAEEL,Caenorhabditis elegans,astral microtubule organization [GO:0030953]; attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation [GO:0051316]; cytoplasmic streaming [GO:0099636]; establishment of mitotic spindle localization [GO:0040001]; meiotic chromosome separation [GO:0051307]; meiotic spindle midzone assembly [GO:0051257]; meiotic spindle organization [GO:0000212]; microtubule polymerization [GO:0046785]; mitotic cytokinesis [GO:0000281]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle midzone assembly [GO:0051256]; sister chromatid biorientation [GO:0031134] comp143980_c0_seq5,2185,46.1785,0.66540969,16,3,,1.00E-180,O75122,CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2),CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2),GO:0005794; GO:0007411; GO:0005938; GO:0051301; GO:0000777; GO:0005881; GO:0005829; GO:0007163; GO:0008107; GO:0005828; GO:0034453; GO:0007020; GO:0005815; GO:0031023; GO:0051010; GO:0007067; GO:0000278; GO:0007026; GO:0032587; GO:0005802,Golgi apparatus; axon guidance; cell cortex; cell division; condensed chromosome kinetochore; cytoplasmic microtubule; cytosol; establishment or maintenance of cell polarity; galactoside 2-alpha-L-fucosyltransferase activity; kinetochore microtubule; microtubule anchoring; microtubule nucleation; microtubule organizing center; microtubule organizing center organization; microtubule plus-end binding; mitosis; mitotic cell cycle; negative regulation of microtubule depolymerization; ruffle membrane; trans-Golgi network,PF12348;,5.00E-81,CHOYP_CLAP1.5.6,,,,,,,CLAP2_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; establishment of protein localization to plasma membrane [GO:0090002]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle organization [GO:0007052]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; sister chromatid cohesion [GO:0007062]; vesicle targeting [GO:0006903]" comp143980_c0_seq6,1316,43.541,0.65977165,2,16,,9.00E-50,Q9NBD7,CLIP-associating protein (Misexpression suppressor of ras 7) (Protein Multiple asters) (Mast) (Protein Orbit) (Protein chromosome bows),CLIP-associating protein (Misexpression suppressor of ras 7) (Protein Multiple asters) (Mast) (Protein Orbit) (Protein chromosome bows),GO:0005525; GO:0051315; GO:0007411; GO:0005813; GO:0000775; GO:0032154; GO:0007282; GO:0040001; GO:0045169; GO:0045172; GO:0030426; GO:0035099; GO:0005875; GO:0008017; GO:0000022; GO:0043148; GO:0046580; GO:0005634; GO:0016325; GO:0030723; GO:0005827; GO:0046602; GO:0051225; GO:0019827,"GTP binding; attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; axon guidance; centrosome; chromosome, centromeric region; cleavage furrow; cystoblast division; establishment of mitotic spindle localization; fusome; germline ring canal; growth cone; hemocyte migration; microtubule associated complex; microtubule binding; mitotic spindle elongation; mitotic spindle stabilization; negative regulation of Ras protein signal transduction; nucleus; oocyte microtubule cytoskeleton organization; ovarian fusome organization; polar microtubule; regulation of mitotic centrosome separation; spindle assembly; stem cell maintenance",PF12348;,2.00E-70,CHOYP_CLAP1.2.6,,,,,,,CLASP_DROME,Drosophila melanogaster (Fruit fly),attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; axon guidance [GO:0007411]; cystoblast division [GO:0007282]; establishment of mitotic spindle localization [GO:0040001]; hemocyte migration [GO:0035099]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; negative regulation of Ras protein signal transduction [GO:0046580]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; ovarian fusome organization [GO:0030723]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic centrosome separation [GO:0046602]; spindle assembly [GO:0051225]; spindle organization [GO:0007051]; stem cell population maintenance [GO:0019827] comp143983_c0_seq1,2160,34.8611,0.66754084,82,183,,1.00E-12,Q15435,Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22),GO:0005737; GO:0005634; GO:0008599,cytoplasm; nucleus; protein phosphatase type 1 regulator activity,,7.00E-92,CHOYP_LOC100749506.1.1,,,,,,,PP1R7_HUMAN,Homo sapiens (Human),chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307] comp143983_c0_seq2,2106,34.9003,0.68427706,0,0,,1.00E-101,O35125,Leucine-rich repeat-containing protein 23 (Leucine-rich protein B7),Leucine-rich repeat-containing protein 23 (Leucine-rich protein B7),,,PF13516;,7.00E-92,CHOYP_LOC100749506.1.1,3.00E-81,ruditapes2_c1802,,,,,LRC23_MOUSE,Mus musculus (Mouse), comp143986_c0_seq7,1404,25.9972,0.33749717,0,0,,2.00E-06,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp143987_c0_seq2,5620,41.1388,0.43803108,4697,543,,0,Q8NHU2,Uncharacterized protein C20orf26,Cilia- and flagella-associated protein 61,,,PF16092;,0,CHOYP_LOC100378255.1.1,5.00E-14,ruditapes_c20131,,,,,CT026_HUMAN,Homo sapiens (Human), comp143988_c0_seq1,556,44.2446,0.52125837,6,23,,4.00E-18,Q4E123,Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap1 2'O-ribose methyltransferase 1) (MTr1),Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap1 2'O-ribose methyltransferase 1) (MTr1),GO:0006370; GO:0097309; GO:0004483; GO:0005634,7-methylguanosine mRNA capping; cap1 mRNA methylation; mRNA (nucleoside-2'-O-)-methyltransferase activity; nucleus,PF01728;,,,,,,,,,MTR1_TRYCC,Trypanosoma cruzi (strain CL Brener),7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009] comp143988_c0_seq2,620,45,0.58708136,5,40,,2.00E-53,Q8IYT2,Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.-) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (HMTr2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) (Protein adrift homolog),Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (HMTr2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) (Protein adrift homolog),GO:0006370; GO:0097310; GO:0005737; GO:0016021; GO:0004483; GO:0005634,7-methylguanosine mRNA capping; cap2 mRNA methylation; cytoplasm; integral to membrane; mRNA (nucleoside-2'-O-)-methyltransferase activity; nucleus,PF01728;,,,,,,,,,FTSJ1_HUMAN,Homo sapiens (Human),7-methylguanosine mRNA capping [GO:0006370]; cap2 mRNA methylation [GO:0097310] comp143989_c0_seq7,244,47.9508,0.28689006,4,29,,,,,,,,,7.00E-11,CHOYP_BRAFLDRAFT_128562.4.4,,,,,,,,, comp143990_c0_seq1,2390,39.8745,0.47767782,54,139,,4.00E-115,Q9DBL7,Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)],Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)],GO:0005524; GO:0015937; GO:0005737; GO:0004140; GO:0005634; GO:0004595,ATP binding; coenzyme A biosynthetic process; cytoplasm; dephospho-CoA kinase activity; nucleus; pantetheine-phosphate adenylyltransferase activity,PF01121;PF01467;,,,,,,,,,COASY_MOUSE,Mus musculus (Mouse),coenzyme A biosynthetic process [GO:0015937] comp143990_c0_seq2,2199,41.0186,0.48159214,47,107,,,,,,,,,2.00E-35,CHOYP_LOC100490454.1.1,,,,,,,,, comp143990_c0_seq3,1773,43.0344,0.45809096,17,17,,9.00E-26,Q9ZPV8,Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (AtCoaD) (Pantetheine-phosphate adenylyltransferase),Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (AtCoaD) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase),GO:0005524; GO:0015937; GO:0005829; GO:0040007; GO:0006629; GO:0019915; GO:0004595; GO:0080020; GO:0009651,ATP binding; coenzyme A biosynthetic process; cytosol; growth; lipid metabolic process; lipid storage; pantetheine-phosphate adenylyltransferase activity; regulation of coenzyme A biosynthetic process; response to salt stress,PF01467;,,,,,,,,,COAD_ARATH,Arabidopsis thaliana (Mouse-ear cress),coenzyme A biosynthetic process [GO:0015937]; growth [GO:0040007]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; regulation of coenzyme A biosynthetic process [GO:0080020]; response to osmotic stress [GO:0006970]; response to salt stress [GO:0009651] comp143990_c0_seq4,3158,38.1571,0.49135091,360,601,,9.00E-113,Q9DBL7,Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)],Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)],GO:0005524; GO:0015937; GO:0005737; GO:0004140; GO:0005634; GO:0004595,ATP binding; coenzyme A biosynthetic process; cytoplasm; dephospho-CoA kinase activity; nucleus; pantetheine-phosphate adenylyltransferase activity,PF01121;PF01467;,,,,,,,,,COASY_MOUSE,Mus musculus (Mouse),coenzyme A biosynthetic process [GO:0015937] comp143991_c0_seq1,1172,44.198,0.28019907,95,439,,7.00E-48,Q6DFB8,Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog),GO:0055087; GO:0005634; GO:0035327,Ski complex; nucleus; transcriptionally active chromatin,PF13181;,,,,,,,,,TTC37_XENLA,Xenopus laevis (African clawed frog), comp143995_c0_seq1,5551,42.2446,0.4333545,1200,3381,,9.00E-127,Q96RT7,Gamma-tubulin complex component 6 (GCP-6),Gamma-tubulin complex component 6 (GCP-6),GO:0000086; GO:0005813; GO:0005829; GO:0008274; GO:0005874; GO:0008017; GO:0007020; GO:0000922,G2/M transition of mitotic cell cycle; centrosome; cytosol; gamma-tubulin ring complex; microtubule; microtubule binding; microtubule nucleation; spindle pole,PF04130;,2.00E-22,CHOYP_TUBGCP6.1.1,,,,,,,GCP6_HUMAN,Homo sapiens (Human),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307] comp143996_c2_seq1,2147,32.7434,0.97359794,35,352,,2.00E-24,P12821,"Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]","Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]",GO:0003779; GO:0002005; GO:0002003; GO:0050482; GO:0001974; GO:0004180; GO:0044267; GO:0031404; GO:0008144; GO:0004175; GO:0005768; GO:0009897; GO:0005615; GO:0060218; GO:0042447; GO:0016021; GO:0001822; GO:0008237; GO:0032943; GO:0043171; GO:0008241; GO:0005886; GO:0006508; GO:0002019; GO:0014910; GO:0019229; GO:0042312; GO:0008270,actin binding; angiotensin catabolic process in blood; angiotensin maturation; arachidonic acid secretion; blood vessel remodeling; carboxypeptidase activity; cellular protein metabolic process; chloride ion binding; drug binding; endopeptidase activity; endosome; external side of plasma membrane; extracellular space; hematopoietic stem cell differentiation; hormone catabolic process; integral to membrane; kidney development; metallopeptidase activity; mononuclear cell proliferation; peptide catabolic process; peptidyl-dipeptidase activity; plasma membrane; proteolysis; regulation of renal output by angiotensin; regulation of smooth muscle cell migration; regulation of vasoconstriction; regulation of vasodilation; zinc ion binding,PF01401;,,,,,,,,,ACE_HUMAN,Homo sapiens (Human),angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; beta-amyloid metabolic process [GO:0050435]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; regulation of vasodilation [GO:0042312]; spermatogenesis [GO:0007283] comp143996_c2_seq2,3579,37.8318,0.90762664,2,81,,0,P12821,"Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]","Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]",GO:0003779; GO:0002005; GO:0002003; GO:0050482; GO:0001974; GO:0004180; GO:0044267; GO:0031404; GO:0008144; GO:0004175; GO:0005768; GO:0009897; GO:0005615; GO:0060218; GO:0042447; GO:0016021; GO:0001822; GO:0008237; GO:0032943; GO:0043171; GO:0008241; GO:0005886; GO:0006508; GO:0002019; GO:0014910; GO:0019229; GO:0042312; GO:0008270,actin binding; angiotensin catabolic process in blood; angiotensin maturation; arachidonic acid secretion; blood vessel remodeling; carboxypeptidase activity; cellular protein metabolic process; chloride ion binding; drug binding; endopeptidase activity; endosome; external side of plasma membrane; extracellular space; hematopoietic stem cell differentiation; hormone catabolic process; integral to membrane; kidney development; metallopeptidase activity; mononuclear cell proliferation; peptide catabolic process; peptidyl-dipeptidase activity; plasma membrane; proteolysis; regulation of renal output by angiotensin; regulation of smooth muscle cell migration; regulation of vasoconstriction; regulation of vasodilation; zinc ion binding,PF01401;,2.00E-127,CHOYP_LOC101076790.1.1,,,,,,,ACE_HUMAN,Homo sapiens (Human),angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; beta-amyloid metabolic process [GO:0050435]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; regulation of vasodilation [GO:0042312]; spermatogenesis [GO:0007283] comp143996_c2_seq3,3561,37.8545,0.89553747,0,40,,0,Q6Q4G4,Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE),Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE),GO:0004180; GO:0005615; GO:0016020; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; extracellular space; membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,,,,,,,,,ACE_THETS,Theromyzon tessulatum (Duck leech), comp143998_c0_seq1,2732,44.9854,0.3257191,82,184,,5.00E-13,Q6AXP1,Uncharacterized protein C19orf44 homolog,Uncharacterized protein C19orf44 homolog,,,PF15391;,,,,,,,,,CS044_RAT,Rattus norvegicus (Rat), comp143999_c1_seq10,3070,39.1857,0.25788955,0,0,,0,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,6.00E-177,CHOYP_HERC1.2.2,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp143999_c1_seq12,5067,42.1157,0.26133002,0,0,,0,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,,,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp143999_c1_seq13,2706,46.748,0.24648682,0,0,,3.00E-111,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,5.00E-57,CHOYP_HERC1.1.2,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp143999_c1_seq3,2574,45.7265,0.29238366,0,0,,1.00E-12,Q6GPC6,F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B),F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B),GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08513;PF00400;,,,,,,,,,TB1RB_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143999_c1_seq6,5093,42.1166,0.26008649,0,0,,0,Q15751,Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619),GO:0005086; GO:0005794; GO:0021702; GO:0005829; GO:0016020; GO:0010507; GO:0050885; GO:0031175; GO:0006810; GO:0004842,ARF guanyl-nucleotide exchange factor activity; Golgi apparatus; cerebellar Purkinje cell differentiation; cytosol; membrane; negative regulation of autophagy; neuromuscular process controlling balance; neuron projection development; transport; ubiquitin-protein ligase activity,PF00632;PF00415;PF00622;PF00400;,0,CHOYP_HERC1.2.2,,,,,,,HERC1_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810] comp143999_c1_seq7,3618,45.0802,0.28916299,0,0,,2.00E-12,Q6GPC6,F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B),F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B),GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08513;PF00400;,,,,,,,,,TB1RB_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp143999_c1_seq8,3044,39.159,0.26026311,0,0,,3.00E-90,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,6.00E-177,CHOYP_HERC1.2.2,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp143999_c1_seq9,1086,46.6851,0.27279024,0,0,,,,,,,,,2.00E-57,CHOYP_HERC1.1.2,,,,,,,,, comp144000_c0_seq1,1716,37.704,0.21861479,18,0,,2.00E-56,Q96EQ9,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0042800; GO:0007126; GO:0046872; GO:0005654; GO:0060903; GO:0010845; GO:0045944; GO:0010844; GO:0043565; GO:0007283; GO:0006351,"chromosome; histone methyltransferase activity (H3-K4 specific); meiosis; metal ion binding; nucleoplasm; positive regulation of meiosis I; positive regulation of reciprocal meiotic recombination; positive regulation of transcription from RNA polymerase II promoter; recombination hotspot binding; sequence-specific DNA binding; spermatogenesis; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;,2.00E-14,CHOYP_PRDM9.1.1,,,,,,,PRDM9_MOUSE,Mus musculus (Mouse),"histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq12,1071,41.7367,0.39138406,20,0,,1.00E-47,Q9NQW5,Probable histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.43) (PR domain zinc finger protein 7) (PR domain-containing protein 7),Probable histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.43) (PR domain zinc finger protein 7) (PR domain-containing protein 7),GO:0005694; GO:0034968; GO:0018024; GO:0003676; GO:0005634; GO:0006355,"chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF09514;,,,,,,,,,PRDM7_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]" comp144000_c0_seq14,1633,37.9669,0.31000802,0,0,,2.00E-47,Q9NQV7,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0034968; GO:0018024; GO:0006311; GO:0046872; GO:0003676; GO:0005654; GO:0010845; GO:0006355; GO:0006351,"chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; meiotic gene conversion; metal ion binding; nucleic acid binding; nucleoplasm; positive regulation of reciprocal meiotic recombination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;PF13912;,,,,,,,,,PRDM9_HUMAN,Homo sapiens (Human),"meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq16,1734,38.293,0.38550214,0,0,,3.00E-57,Q96EQ9,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0042800; GO:0007126; GO:0046872; GO:0005654; GO:0060903; GO:0010845; GO:0045944; GO:0010844; GO:0043565; GO:0007283; GO:0006351,"chromosome; histone methyltransferase activity (H3-K4 specific); meiosis; metal ion binding; nucleoplasm; positive regulation of meiosis I; positive regulation of reciprocal meiotic recombination; positive regulation of transcription from RNA polymerase II promoter; recombination hotspot binding; sequence-specific DNA binding; spermatogenesis; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;,,,,,,,,,PRDM9_MOUSE,Mus musculus (Mouse),"histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq17,1216,40.7895,0.28232935,3,0,,2.00E-25,A2AGX3,PR domain-containing protein 11 (EC 2.1.1.-),PR domain-containing protein 11 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF00856;,2.00E-14,CHOYP_PRDM9.1.1,,,,,,,PRD11_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq18,1709,38.0925,0.32951798,20,0,,1.00E-24,Q9NQV5,PR domain-containing protein 11 (EC 2.1.1.-),PR domain-containing protein 11 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF00856;,,,,,,,,,PRD11_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq20,1064,40.7895,0.2308795,0,0,,2.00E-25,Q9NQV5,PR domain-containing protein 11 (EC 2.1.1.-),PR domain-containing protein 11 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF00856;,,,,,,,,,PRD11_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq25,1409,37.4024,0.20704856,0,0,,2.00E-20,Q9NQV6,PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin),PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;PF12171;,,,,,,,,,PRD10_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq26,1268,37.8549,0.24701401,0,0,,4.00E-52,P0C6Y7,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0034968; GO:0018024; GO:0007126; GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; meiosis; metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;,2.00E-14,CHOYP_PRDM9.1.1,,,,,,,PRDM9_RAT,Rattus norvegicus (Rat),"meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq27,1723,37.6088,0.2854528,0,0,,1.00E-49,Q96EQ9,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0042800; GO:0007126; GO:0046872; GO:0005654; GO:0060903; GO:0010845; GO:0045944; GO:0010844; GO:0043565; GO:0007283; GO:0006351,"chromosome; histone methyltransferase activity (H3-K4 specific); meiosis; metal ion binding; nucleoplasm; positive regulation of meiosis I; positive regulation of reciprocal meiotic recombination; positive regulation of transcription from RNA polymerase II promoter; recombination hotspot binding; sequence-specific DNA binding; spermatogenesis; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;,,,,,,,,,PRDM9_MOUSE,Mus musculus (Mouse),"histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq29,1781,38.2931,0.38874358,0,0,,3.00E-57,Q96EQ9,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0042800; GO:0007126; GO:0046872; GO:0005654; GO:0060903; GO:0010845; GO:0045944; GO:0010844; GO:0043565; GO:0007283; GO:0006351,"chromosome; histone methyltransferase activity (H3-K4 specific); meiosis; metal ion binding; nucleoplasm; positive regulation of meiosis I; positive regulation of reciprocal meiotic recombination; positive regulation of transcription from RNA polymerase II promoter; recombination hotspot binding; sequence-specific DNA binding; spermatogenesis; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;,,,,,,,,,PRDM9_MOUSE,Mus musculus (Mouse),"histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq3,1788,37.8635,0.27009298,11,0,,7.00E-13,Q9NQX1,PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5),PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5),GO:0051567; GO:0016575; GO:0046872; GO:0008168; GO:0000278; GO:0045892; GO:0005634; GO:0070491; GO:0043565; GO:0044212; GO:0000976; GO:0006351,"histone H3-K9 methylation; histone deacetylation; metal ion binding; methyltransferase activity; mitotic cell cycle; negative regulation of transcription, DNA-dependent; nucleus; repressing transcription factor binding; sequence-specific DNA binding; transcription regulatory region DNA binding; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,PRDM5_HUMAN,Homo sapiens (Human),"histone deacetylation [GO:0016575]; histone H3-K9 methylation [GO:0051567]; mitotic cell cycle [GO:0000278]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq30,1046,40.2486,0.26477104,0,0,,2.00E-46,Q9NQW5,Probable histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.43) (PR domain zinc finger protein 7) (PR domain-containing protein 7),Probable histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.43) (PR domain zinc finger protein 7) (PR domain-containing protein 7),GO:0005694; GO:0034968; GO:0018024; GO:0003676; GO:0005634; GO:0006355,"chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF09514;,1.00E-14,CHOYP_PRDM9.1.1,,,,,,,PRDM7_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]" comp144000_c0_seq5,1698,37.3969,0.2411298,0,0,,4.00E-51,P0C6Y7,Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9),GO:0005694; GO:0034968; GO:0018024; GO:0007126; GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; meiosis; metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00856;PF09514;PF00096;,,,,,,,,,PRDM9_RAT,Rattus norvegicus (Rat),"meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144000_c0_seq6,1234,41.329,0.27130524,0,0,,2.00E-19,O75626,PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1),GO:0045165; GO:0005737; GO:0001892; GO:0042462; GO:0007281; GO:0001893; GO:0046872; GO:0008168; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0043565; GO:0003700; GO:0006351,"cell fate commitment; cytoplasm; embryonic placenta development; eye photoreceptor cell development; germ cell development; maternal placenta development; metal ion binding; methyltransferase activity; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00856;PF13912;,,,,,,,,,PRDM1_HUMAN,Homo sapiens (Human),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp144000_c0_seq9,1741,37.8518,0.26264615,0,0,,1.00E-24,Q9NQV5,PR domain-containing protein 11 (EC 2.1.1.-),PR domain-containing protein 11 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF00856;,,,,,,,,,PRD11_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144001_c0_seq1,3216,46.3308,0.69698798,0,0,,,,,,,,,7.00E-126,CHOYP_HIPK2.1.2,,,,,,,,, comp144001_c0_seq10,1548,44.7028,0.89405041,0,0,,0,Q9H2X6,Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1),Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1),GO:0005524; GO:0006978; GO:0016605; GO:0030578; GO:0001102; GO:0001105; GO:0060395; GO:0007628; GO:0009952; GO:0071456; GO:0005813; GO:0005737; GO:0048596; GO:0060059; GO:0030218; GO:0001654; GO:0042771; GO:0061072; GO:0060235; GO:0019048; GO:0030514; GO:0043524; GO:0000122; GO:0030182; GO:0016604; GO:0031965; GO:0018105; GO:0018107; GO:0043388; GO:0046330; GO:0045766; GO:0008284; GO:0032092; GO:0051091; GO:0045944; GO:0030511; GO:0004674; GO:0051726; GO:0010842; GO:0007224; GO:0003714; GO:0007179; GO:0046790; GO:0050882,"ATP binding; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; PML body; PML body organization; RNA polymerase II activating transcription factor binding; RNA polymerase II transcription coactivator activity; SMAD protein signal transduction; adult walking behavior; anterior/posterior pattern specification; cellular response to hypoxia; centrosome; cytoplasm; embryonic camera-type eye morphogenesis; embryonic retina morphogenesis in camera-type eye; erythrocyte differentiation; eye development; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; iris morphogenesis; lens induction in camera-type eye; modulation by virus of host morphology or physiology; negative regulation of BMP signaling pathway; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; nuclear body; nuclear membrane; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of DNA binding; positive regulation of JNK cascade; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of protein binding; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; protein serine/threonine kinase activity; regulation of cell cycle; retina layer formation; smoothened signaling pathway; transcription corepressor activity; transforming growth factor beta receptor signaling pathway; virion binding; voluntary musculoskeletal movement",PF00069;,,,,,,,,,HIPK2_HUMAN,Homo sapiens (Human),"adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; erythrocyte differentiation [GO:0030218]; eye development [GO:0001654]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of signal transduction by p53 class mediator [GO:1901796]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882]" comp144001_c0_seq2,1220,42.7869,1.02348598,0,3,,4.00E-23,Q54UA9,Probable serine/threonine-protein kinase clkA (EC 2.7.11.1) (CDC2-like kinase A),Probable serine/threonine-protein kinase clkA (EC 2.7.11.1) (CDC2-like kinase A),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,CLKA_DICDI,Dictyostelium discoideum (Slime mold),protein phosphorylation [GO:0006468] comp144001_c0_seq3,4531,46.0384,0.76356148,4,0,,0,Q9QZR5,Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase),Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase),GO:0005524; GO:0006978; GO:0016605; GO:0060395; GO:0007628; GO:0009952; GO:0005813; GO:0005737; GO:0048596; GO:0060059; GO:0042771; GO:0061072; GO:0060235; GO:0030514; GO:0043524; GO:0000122; GO:0030182; GO:0031965; GO:0018105; GO:0018107; GO:0043388; GO:0046330; GO:0045766; GO:0008284; GO:0032092; GO:0051091; GO:0045944; GO:0030511; GO:0004674; GO:0010842; GO:0007224; GO:0003714; GO:0006351; GO:0007179; GO:0046790; GO:0050882,"ATP binding; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; PML body; SMAD protein signal transduction; adult walking behavior; anterior/posterior pattern specification; centrosome; cytoplasm; embryonic camera-type eye morphogenesis; embryonic retina morphogenesis in camera-type eye; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; iris morphogenesis; lens induction in camera-type eye; negative regulation of BMP signaling pathway; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; nuclear membrane; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of DNA binding; positive regulation of JNK cascade; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of protein binding; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; protein serine/threonine kinase activity; retina layer formation; smoothened signaling pathway; transcription corepressor activity; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; virion binding; voluntary musculoskeletal movement",PF00069;,0,CHOYP_HIPK2.1.2,,,,,,,HIPK2_MOUSE,Mus musculus (Mouse),"adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882]" comp144001_c0_seq4,3229,46.2682,0.6960545,0,0,,,,,,,,,,,1.00E-38,ruditapes_c28816,,,,,,, comp144001_c0_seq7,4541,46.0031,0.75884851,27,30,,0,Q9QZR5,Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase),Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase),GO:0005524; GO:0006978; GO:0016605; GO:0060395; GO:0007628; GO:0009952; GO:0005813; GO:0005737; GO:0048596; GO:0060059; GO:0042771; GO:0061072; GO:0060235; GO:0030514; GO:0043524; GO:0000122; GO:0030182; GO:0031965; GO:0018105; GO:0018107; GO:0043388; GO:0046330; GO:0045766; GO:0008284; GO:0032092; GO:0051091; GO:0045944; GO:0030511; GO:0004674; GO:0010842; GO:0007224; GO:0003714; GO:0006351; GO:0007179; GO:0046790; GO:0050882,"ATP binding; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; PML body; SMAD protein signal transduction; adult walking behavior; anterior/posterior pattern specification; centrosome; cytoplasm; embryonic camera-type eye morphogenesis; embryonic retina morphogenesis in camera-type eye; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; iris morphogenesis; lens induction in camera-type eye; negative regulation of BMP signaling pathway; negative regulation of neuron apoptotic process; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; nuclear membrane; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of DNA binding; positive regulation of JNK cascade; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of protein binding; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor beta receptor signaling pathway; protein serine/threonine kinase activity; retina layer formation; smoothened signaling pathway; transcription corepressor activity; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; virion binding; voluntary musculoskeletal movement",PF00069;,,,,,,,,,HIPK2_MOUSE,Mus musculus (Mouse),"adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882]" comp144001_c0_seq8,3301,47.0161,0.66991616,0,0,,,,,,,,,1.00E-160,CHOYP_HIPK2.1.2,,,,,,,,, comp144001_c0_seq9,3313,46.9665,0.66889357,0,0,,,,,,,,,1.00E-153,CHOYP_HIPK2.2.2,,,,,,,,, comp144003_c1_seq1,2893,41.1338,0.44248037,120,635,,1.00E-149,Q5C9Z4,Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog),Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog),GO:0003723; GO:0005730,RNA binding; nucleolus,PF02847;PF02854;,3.00E-48,CHOYP_LOC659901.1.1,,,,,,,NOM1_HUMAN,Homo sapiens (Human),neurogenesis [GO:0022008]; ribosomal small subunit biogenesis [GO:0042274] comp144003_c1_seq2,1597,43.7696,0.38507959,67,158,,3.00E-153,Q3UFM5,Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog),Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog),GO:0003723; GO:0005730,RNA binding; nucleolus,PF02847;PF02854;,2.00E-47,CHOYP_LOC659901.1.1,,,,,,,NOM1_MOUSE,Mus musculus (Mouse),neurogenesis [GO:0022008]; ribosomal small subunit biogenesis [GO:0042274] comp144006_c0_seq1,2112,40.7197,0.30959714,405,2275,,2.00E-28,Q6INI5,Nucleolar protein 11,Nucleolar protein 11,GO:0030490; GO:0005730; GO:1901838; GO:0006351,"maturation of SSU-rRNA; nucleolus; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; transcription, DNA-dependent",,,,,,,,,,NOL11_XENLA,Xenopus laevis (African clawed frog),"maturation of SSU-rRNA [GO:0030490]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; transcription, DNA-templated [GO:0006351]" comp144007_c0_seq1,2238,40.706,0.52579267,48,278,,1.00E-18,Q8YTC2,Uncharacterized WD repeat-containing protein alr2800,Uncharacterized WD repeat-containing protein alr2800,GO:0043531; GO:0006952; GO:0006355,"ADP binding; defense response; regulation of transcription, DNA-dependent",PF00931;PF00400;,6.00E-144,CHOYP_DCA13.1.1,,,,,,,Y2800_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp144007_c0_seq2,2288,40.4283,0.52115024,81,261,,0,Q5ZLK1,DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1),DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1),GO:0080008; GO:0005730; GO:0016567; GO:0006364; GO:0030529,Cul4-RING ubiquitin ligase complex; nucleolus; protein ubiquitination; rRNA processing; ribonucleoprotein complex,PF04158;PF00400;,6.00E-144,CHOYP_DCA13.1.1,,,,,,,DCA13_CHICK,Gallus gallus (Chicken),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; protein ubiquitination [GO:0016567]" comp144008_c1_seq2,907,42.2271,0.63146991,117,765,,2.00E-52,Q9Y4Z0,U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP),U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP),GO:0003723; GO:0008380; GO:0005688; GO:0005829; GO:0043928; GO:0006397; GO:0005681,RNA binding; RNA splicing; U6 snRNP; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; mRNA processing; spliceosomal complex,PF01423;,4.00E-91,CHOYP_LSM4.3.3,,,,,,,LSM4_HUMAN,Homo sapiens (Human),"cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of defense response to virus by host [GO:0002230]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; xenophagy [GO:0098792]" comp144010_c0_seq2,3110,34.2122,0.58696448,81,233,,4.00E-33,Q90655,Homeobox protein AKR (Avian knotted-related protein),Homeobox protein AKR (Avian knotted-related protein),GO:0003677; GO:0045892; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"DNA binding; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF05920;,6.00E-38,CHOYP_LOC100901362.1.1,,,,,,,AKR_CHICK,Gallus gallus (Chicken),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp144011_c0_seq1,2995,41.5025,0.71052255,3,0,,3.00E-46,Q80TG1,KAT8 regulatory NSL complex subunit 1 (NSL complex protein NSL1) (Non-specific lethal 1 homolog),KAT8 regulatory NSL complex subunit 1 (NSL complex protein NSL1) (Non-specific lethal 1 homolog),GO:0071339; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123,MLL1 complex; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex,PF15275;,,,,,,,,,KANL1_MOUSE,Mus musculus (Mouse),histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982] comp144011_c0_seq3,4778,41.8794,0.72299987,222,372,,1.00E-46,Q80TG1,KAT8 regulatory NSL complex subunit 1 (NSL complex protein NSL1) (Non-specific lethal 1 homolog),KAT8 regulatory NSL complex subunit 1 (NSL complex protein NSL1) (Non-specific lethal 1 homolog),GO:0071339; GO:0043984; GO:0043981; GO:0043982; GO:0046972; GO:0043995; GO:0043996; GO:0000123,MLL1 complex; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase complex,PF15275;,3.00E-49,CHOYP_LOC100375819.1.1,2.00E-19,ruditapes_c21135,,,,,KANL1_MOUSE,Mus musculus (Mouse),histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982] comp144012_c3_seq1,3178,37.0988,1.02714065,7,68,,1.00E-20,P01025,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2],Complement C3 [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2],GO:0031715; GO:0006957; GO:0006958; GO:0004866; GO:0005615; GO:0006631; GO:0006954; GO:0010951; GO:0045745; GO:0010828; GO:0010884; GO:0001934; GO:0010866,"C5L2 anaphylatoxin chemotactic receptor binding; complement activation, alternative pathway; complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; fatty acid metabolic process; inflammatory response; negative regulation of endopeptidase activity; positive regulation of G-protein coupled receptor protein signaling pathway; positive regulation of glucose transport; positive regulation of lipid storage; positive regulation of protein phosphorylation; regulation of triglyceride biosynthetic process",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_PIG,Sus scrofa (Pig),"complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of glucose transport [GO:0010828]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]" comp144012_c3_seq2,3098,37.2498,1.03621143,8,138,,4.00E-27,Q00685,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment),Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment),GO:0006958; GO:0004866; GO:0005615; GO:0006954; GO:0045087; GO:0010951,"complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; inflammatory response; innate immune response; negative regulation of endopeptidase activity",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_LAMJA,Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica),"complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]" comp144012_c3_seq3,3733,36.4318,0.97970192,106,945,,6.00E-27,Q00685,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment),Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment),GO:0006958; GO:0004866; GO:0005615; GO:0006954; GO:0045087; GO:0010951,"complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; inflammatory response; innate immune response; negative regulation of endopeptidase activity",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_LAMJA,Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica),"complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]" comp144013_c0_seq1,271,39.4834,0.19047878,0,0,,2.00E-08,Q3BJS0,Forkhead box protein N5,Forkhead box protein N5,GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXN5_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq11,4409,37.4915,0.31642068,0,0,,3.00E-06,Q8BUR3,Forkhead box protein J3,Forkhead box protein J3,GO:0008301; GO:0009790; GO:0005634; GO:0007389; GO:0045893; GO:0043565; GO:0003700; GO:0009888; GO:0006351,"DNA binding, bending; embryo development; nucleus; pattern specification process; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; tissue development; transcription, DNA-dependent",PF00250;,1.00E-16,CHOYP_contig_042154,,,,,,,FOXJ3_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq12,1062,42.5612,0.16651017,0,0,,2.00E-08,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,3.00E-17,CHOYP_contig_042154,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq13,722,42.5208,0.21479542,0,0,,3.00E-09,Q7ZYQ0,Forkhead box protein I1-ema (FoxI1-ema) (Ectodermally-expressed mesendoderm antagonist) (Xema) (FoxI3),Forkhead box protein I1-ema (FoxI1-ema) (Ectodermally-expressed mesendoderm antagonist) (Xema) (FoxI3),GO:0007275; GO:0042664; GO:0048335; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"multicellular organismal development; negative regulation of endodermal cell fate specification; negative regulation of mesodermal cell fate determination; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FXI1E_XENLA,Xenopus laevis (African clawed frog),"multicellular organism development [GO:0007275]; negative regulation of endodermal cell fate specification [GO:0042664]; negative regulation of mesodermal cell fate determination [GO:0048335]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq19,3589,40.0669,0.34028768,0,0,,2.00E-08,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq2,1670,41.976,0.25908254,0,0,,9.00E-09,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq20,2561,39.1644,0.25505535,0,0,,1.00E-08,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,7.00E-17,CHOYP_contig_042154,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq21,3247,37.9427,0.27407045,0,0,,,,,,,,,9.00E-17,CHOYP_contig_042154,,,,,,,,, comp144013_c0_seq26,1102,37.931,0.55707117,172,13,,4.00E-07,Q3BJS0,Forkhead box protein N5,Forkhead box protein N5,GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXN5_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq28,1803,42.6511,0.29307529,0,0,,7.00E-09,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq30,913,42.3877,0.17090522,0,0,,2.00E-08,Q9C009,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0008301; GO:0003705; GO:0003690; GO:0009790; GO:0031069; GO:0000122; GO:0005634; GO:0007389; GO:0051090; GO:0043565; GO:0009888; GO:0008134; GO:0005667,"DNA binding, bending; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; double-stranded DNA binding; embryo development; hair follicle morphogenesis; negative regulation of transcription from RNA polymerase II promoter; nucleus; pattern specification process; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; tissue development; transcription factor binding; transcription factor complex",PF00250;,2.00E-17,CHOYP_contig_042154,,,,,,,FOXQ1_HUMAN,Homo sapiens (Human),"hair follicle morphogenesis [GO:0031069]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq31,2916,41.5638,0.31772574,0,0,,5.00E-06,Q32NP8,Forkhead box protein C1-B,Forkhead box protein C1-B,GO:0003677; GO:0007155; GO:0007498; GO:0005634; GO:0048793; GO:0006355; GO:0043565; GO:0003700; GO:0006351,"DNA binding; cell adhesion; mesoderm development; nucleus; pronephros development; regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,,,,,,,,,FXC1B_XENLA,Xenopus laevis (African clawed frog),"cell adhesion [GO:0007155]; mesoderm development [GO:0007498]; pronephros development [GO:0048793]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq35,2125,42.1176,0.26581651,0,9,,1.00E-06,Q6NVT7,Forkhead box protein C2 (FoxC2),Forkhead box protein C2 (FoxC2),GO:0008301; GO:0007219; GO:0003705; GO:0048844; GO:0001974; GO:0043010; GO:0060038; GO:0031490; GO:0030199; GO:0003690; GO:0035050; GO:0048703; GO:0008286; GO:0001946; GO:0001656; GO:0043066; GO:0000122; GO:0005634; GO:0001503; GO:0048343; GO:0001569; GO:0045944; GO:0050880; GO:0046620; GO:0051090; GO:0043565; GO:0001756; GO:0008134; GO:0005667; GO:0001657; GO:0048010; GO:0055010,"DNA binding, bending; Notch signaling pathway; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; artery morphogenesis; blood vessel remodeling; camera-type eye development; cardiac muscle cell proliferation; chromatin DNA binding; collagen fibril organization; double-stranded DNA binding; embryonic heart tube development; embryonic viscerocranium morphogenesis; insulin receptor signaling pathway; lymphangiogenesis; metanephros development; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; ossification; paraxial mesodermal cell fate commitment; patterning of blood vessels; positive regulation of transcription from RNA polymerase II promoter; regulation of blood vessel size; regulation of organ growth; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; somitogenesis; transcription factor binding; transcription factor complex; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle tissue morphogenesis",PF00250;,,,,,,,,,FOXC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq36,1980,40.0505,0.21450051,0,0,,,,,,,,,5.00E-17,CHOYP_contig_042154,,,,,,,,, comp144013_c0_seq37,3086,37.0706,0.27432183,0,0,,1.00E-06,Q6NVT7,Forkhead box protein C2 (FoxC2),Forkhead box protein C2 (FoxC2),GO:0008301; GO:0007219; GO:0003705; GO:0048844; GO:0001974; GO:0043010; GO:0060038; GO:0031490; GO:0030199; GO:0003690; GO:0035050; GO:0048703; GO:0008286; GO:0001946; GO:0001656; GO:0043066; GO:0000122; GO:0005634; GO:0001503; GO:0048343; GO:0001569; GO:0045944; GO:0050880; GO:0046620; GO:0051090; GO:0043565; GO:0001756; GO:0008134; GO:0005667; GO:0001657; GO:0048010; GO:0055010,"DNA binding, bending; Notch signaling pathway; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; artery morphogenesis; blood vessel remodeling; camera-type eye development; cardiac muscle cell proliferation; chromatin DNA binding; collagen fibril organization; double-stranded DNA binding; embryonic heart tube development; embryonic viscerocranium morphogenesis; insulin receptor signaling pathway; lymphangiogenesis; metanephros development; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; ossification; paraxial mesodermal cell fate commitment; patterning of blood vessels; positive regulation of transcription from RNA polymerase II promoter; regulation of blood vessel size; regulation of organ growth; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; somitogenesis; transcription factor binding; transcription factor complex; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle tissue morphogenesis",PF00250;,,,,,,,,,FOXC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq38,2505,37.2056,0.23141568,0,0,,2.00E-08,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,7.00E-17,CHOYP_contig_042154,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144013_c0_seq5,5259,36.0905,0.29203241,0,0,,2.00E-06,Q6NVT7,Forkhead box protein C2 (FoxC2),Forkhead box protein C2 (FoxC2),GO:0008301; GO:0007219; GO:0003705; GO:0048844; GO:0001974; GO:0043010; GO:0060038; GO:0031490; GO:0030199; GO:0003690; GO:0035050; GO:0048703; GO:0008286; GO:0001946; GO:0001656; GO:0043066; GO:0000122; GO:0005634; GO:0001503; GO:0048343; GO:0001569; GO:0045944; GO:0050880; GO:0046620; GO:0051090; GO:0043565; GO:0001756; GO:0008134; GO:0005667; GO:0001657; GO:0048010; GO:0055010,"DNA binding, bending; Notch signaling pathway; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; artery morphogenesis; blood vessel remodeling; camera-type eye development; cardiac muscle cell proliferation; chromatin DNA binding; collagen fibril organization; double-stranded DNA binding; embryonic heart tube development; embryonic viscerocranium morphogenesis; insulin receptor signaling pathway; lymphangiogenesis; metanephros development; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; ossification; paraxial mesodermal cell fate commitment; patterning of blood vessels; positive regulation of transcription from RNA polymerase II promoter; regulation of blood vessel size; regulation of organ growth; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; somitogenesis; transcription factor binding; transcription factor complex; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle tissue morphogenesis",PF00250;,,,,,,,,,FOXC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq7,2251,40.4709,0.29377609,0,0,,7.00E-07,Q6NVT7,Forkhead box protein C2 (FoxC2),Forkhead box protein C2 (FoxC2),GO:0008301; GO:0007219; GO:0003705; GO:0048844; GO:0001974; GO:0043010; GO:0060038; GO:0031490; GO:0030199; GO:0003690; GO:0035050; GO:0048703; GO:0008286; GO:0001946; GO:0001656; GO:0043066; GO:0000122; GO:0005634; GO:0001503; GO:0048343; GO:0001569; GO:0045944; GO:0050880; GO:0046620; GO:0051090; GO:0043565; GO:0001756; GO:0008134; GO:0005667; GO:0001657; GO:0048010; GO:0055010,"DNA binding, bending; Notch signaling pathway; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; artery morphogenesis; blood vessel remodeling; camera-type eye development; cardiac muscle cell proliferation; chromatin DNA binding; collagen fibril organization; double-stranded DNA binding; embryonic heart tube development; embryonic viscerocranium morphogenesis; insulin receptor signaling pathway; lymphangiogenesis; metanephros development; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; ossification; paraxial mesodermal cell fate commitment; patterning of blood vessels; positive regulation of transcription from RNA polymerase II promoter; regulation of blood vessel size; regulation of organ growth; regulation of sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; somitogenesis; transcription factor binding; transcription factor complex; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle tissue morphogenesis",PF00250;,,,,,,,,,FOXC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]" comp144013_c0_seq9,1655,41.4502,0.26788598,0,0,,9.00E-09,Q63244,Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1),GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,4.00E-17,CHOYP_contig_042154,,,,,,,FOXQ1_RAT,Rattus norvegicus (Rat),"transcription, DNA-templated [GO:0006351]" comp144014_c0_seq1,3026,38.9954,0.43387191,32,158,,0,Q00004,Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein),Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein),GO:0008312; GO:0006614; GO:0005829; GO:0030942; GO:0005730; GO:0042493; GO:0005047; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosol; endoplasmic reticulum signal peptide binding; nucleolus; response to drug; signal recognition particle binding; signal recognition particle, endoplasmic reticulum targeting",PF16969;,,,,,,,,,SRP68_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp144014_c0_seq2,2981,39.0473,0.44033335,0,46,,0,Q00004,Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein),Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein),GO:0008312; GO:0006614; GO:0005829; GO:0030942; GO:0005730; GO:0042493; GO:0005047; GO:0005786,"7S RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosol; endoplasmic reticulum signal peptide binding; nucleolus; response to drug; signal recognition particle binding; signal recognition particle, endoplasmic reticulum targeting",PF16969;,2.00E-118,CHOYP_SRP68.1.1,,,,,,,SRP68_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp144015_c1_seq1,1324,42.8248,0.69288849,0,0,,4.00E-155,Q64536,"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)","[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)",GO:0005524; GO:0031670; GO:0042593; GO:0006006; GO:0008286; GO:0005967; GO:0018105; GO:0032403; GO:0046982; GO:0042803; GO:0004674; GO:0004740; GO:0010510; GO:0006111; GO:0006885,ATP binding; cellular response to nutrient; glucose homeostasis; glucose metabolic process; insulin receptor signaling pathway; mitochondrial pyruvate dehydrogenase complex; peptidyl-serine phosphorylation; protein complex binding; protein heterodimerization activity; protein homodimerization activity; protein serine/threonine kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; regulation of acetyl-CoA biosynthetic process from pyruvate; regulation of gluconeogenesis; regulation of pH,PF10436;PF02518;,,,,,,,,,PDK2_RAT,Rattus norvegicus (Rat),cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] comp144015_c1_seq3,1205,43.7344,0.66152826,0,0,,2.00E-157,Q64536,"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)","[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)",GO:0005524; GO:0031670; GO:0042593; GO:0006006; GO:0008286; GO:0005967; GO:0018105; GO:0032403; GO:0046982; GO:0042803; GO:0004674; GO:0004740; GO:0010510; GO:0006111; GO:0006885,ATP binding; cellular response to nutrient; glucose homeostasis; glucose metabolic process; insulin receptor signaling pathway; mitochondrial pyruvate dehydrogenase complex; peptidyl-serine phosphorylation; protein complex binding; protein heterodimerization activity; protein homodimerization activity; protein serine/threonine kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; regulation of acetyl-CoA biosynthetic process from pyruvate; regulation of gluconeogenesis; regulation of pH,PF10436;PF02518;,2.00E-32,CHOYP_BRAFLDRAFT_114859.1.1,6.00E-62,ruditapes2_c211,,,,,PDK2_RAT,Rattus norvegicus (Rat),cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] comp144015_c1_seq9,1397,43.3071,0.70417451,0,0,,2.00E-141,O70571,"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)","[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)",GO:0005524; GO:0006086; GO:0071398; GO:0009267; GO:0042593; GO:0006006; GO:0008286; GO:0005743; GO:0005759; GO:2000811; GO:0004674; GO:0004712; GO:0004740; GO:0072593; GO:0010510; GO:0045124; GO:0042304; GO:0046320; GO:0010906; GO:0006885,ATP binding; acetyl-CoA biosynthetic process from pyruvate; cellular response to fatty acid; cellular response to starvation; glucose homeostasis; glucose metabolic process; insulin receptor signaling pathway; mitochondrial inner membrane; mitochondrial matrix; negative regulation of anoikis; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; reactive oxygen species metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; regulation of bone resorption; regulation of fatty acid biosynthetic process; regulation of fatty acid oxidation; regulation of glucose metabolic process; regulation of pH,PF10436;PF02518;,,,,,,,,,PDK4_MOUSE,Mus musculus (Mouse),cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; negative regulation of anoikis [GO:2000811]; positive regulation of defense response to virus by host [GO:0002230]; reactive oxygen species metabolic process [GO:0072593]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of bone resorption [GO:0045124]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]; response to starvation [GO:0042594]; xenophagy [GO:0098792] comp144017_c0_seq1,3011,40.352,0.39516327,13,17,,0,Q0VFR9,Mediator of RNA polymerase II transcription subunit 17 (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17),Mediator of RNA polymerase II transcription subunit 17 (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF10156;,1.00E-65,CHOYP_MED17.1.1,7.00E-22,ruditapes_lrc17751,,,,,MED17_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"transcription, DNA-templated [GO:0006351]" comp144021_c0_seq1,3904,33.6322,0.31965528,31,126,,4.00E-81,Q9VXK0,Protein NipSnap,Protein NipSnap,,,PF07978;,2.00E-83,CHOYP_DMOJ_GI11203.1.1,,,,,,,NIPSN_DROME,Drosophila melanogaster (Fruit fly), comp144021_c0_seq3,4272,33.4972,0.320373,707,2187,,9.00E-81,Q9VXK0,Protein NipSnap,Protein NipSnap,,,PF07978;,,,2.00E-80,ruditapes_c21036,,,,,NIPSN_DROME,Drosophila melanogaster (Fruit fly), comp144024_c0_seq4,1887,40.8055,0.41809235,292,900,,0,P70076,"Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)","Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)",GO:0005524; GO:0005737; GO:0004821; GO:0006427,ATP binding; cytoplasm; histidine-tRNA ligase activity; histidyl-tRNA aminoacylation,PF03129;,0,CHOYP_SYHC.1.1,,,,,,,SYHC_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543] comp144025_c0_seq1,4316,41.1956,0.37242737,27,154,,5.00E-17,Q6DRL5,Myb-binding protein 1A-like protein,Myb-binding protein 1A-like protein,GO:0003677; GO:0003887; GO:0005730; GO:0006355; GO:0006351,"DNA binding; DNA-directed DNA polymerase activity; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF04931;,,,,,,,,,MBB1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144025_c0_seq2,4343,41.3309,0.37344784,23,130,,2.00E-09,Q9BQG0,Myb-binding protein 1A,Myb-binding protein 1A,GO:0003887; GO:0042564; GO:0042149; GO:0005737; GO:0072332; GO:0045892; GO:0006913; GO:0005730; GO:0071158; GO:0006355; GO:0022904; GO:0043565; GO:0008134; GO:0006351,"DNA-directed DNA polymerase activity; NLS-dependent protein nuclear import complex; cellular response to glucose starvation; cytoplasm; intrinsic apoptotic signaling pathway by p53 class mediator; negative regulation of transcription, DNA-dependent; nucleocytoplasmic transport; nucleolus; positive regulation of cell cycle arrest; regulation of transcription, DNA-dependent; respiratory electron transport chain; sequence-specific DNA binding; transcription factor binding; transcription, DNA-dependent",PF04931;,,,,,,,,,MBB1A_HUMAN,Homo sapiens (Human),"cellular response to glucose starvation [GO:0042149]; circadian regulation of gene expression [GO:0032922]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleocytoplasmic transport [GO:0006913]; osteoblast differentiation [GO:0001649]; positive regulation of anoikis [GO:2000210]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of gene expression, epigenetic [GO:0045815]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]" comp144027_c0_seq11,1157,42.2645,1.08834668,0,0,,4.00E-57,P07207,Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],GO:0005796; GO:0061382; GO:0007219; GO:0048052; GO:0007464; GO:0045466; GO:0045463; GO:0007460; GO:0007015; GO:0005912; GO:0008356; GO:0007298; GO:0005509; GO:0009986; GO:0008407; GO:0003682; GO:0042676; GO:0046667; GO:0005829; GO:0008340; GO:0046843; GO:0007391; GO:0007451; GO:0007398; GO:0035165; GO:0005788; GO:0005768; GO:0061331; GO:0035153; GO:0035214; GO:0007440; GO:0060288; GO:0030718; GO:0030708; GO:0007403; GO:0008347; GO:0035172; GO:0007157; GO:0007446; GO:0016348; GO:0048803; GO:0008587; GO:0007474; GO:0016021; GO:0035171; GO:0046331; GO:0007616; GO:0035170; GO:0007498; GO:0008045; GO:0007521; GO:0046329; GO:0045316; GO:0035157; GO:0050768; GO:0035155; GO:0000122; GO:0007400; GO:0005654; GO:0007314; GO:0030720; GO:0030713; GO:0007422; GO:1900087; GO:0045747; GO:0008284; GO:0045944; GO:0043234; GO:0045468; GO:0042686; GO:0042689; GO:0051489; GO:0040008; GO:0009608; GO:0016330; GO:0007519; GO:0035003; GO:0006351; GO:0004888; GO:0007419; GO:0048190; GO:0007473,"Golgi lumen; Malpighian tubule tip cell differentiation; Notch signaling pathway; R1/R6 cell differentiation; R3/R4 cell fate commitment; R7 cell differentiation; R8 cell development; R8 cell fate commitment; actin filament organization; adherens junction; asymmetric cell division; border follicle cell migration; calcium ion binding; cell surface; chaeta morphogenesis; chromatin binding; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; cytosol; determination of adult lifespan; dorsal appendage formation; dorsal closure; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; embryonic crystal cell differentiation; endoplasmic reticulum lumen; endosome; epithelial cell proliferation involved in Malpighian tubule morphogenesis; epithelial cell type specification, open tracheal system; eye-antennal disc development; foregut morphogenesis; formation of a compartment boundary; germ-line stem cell maintenance; germarium-derived female germ-line cyst encapsulation; glial cell fate determination; glial cell migration; hemocyte proliferation; heterophilic cell-cell adhesion; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived male genitalia morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; lamellocyte differentiation; lateral inhibition; long-term memory; lymph gland crystal cell differentiation; mesoderm development; motor neuron axon guidance; muscle cell fate determination; negative regulation of JNK cascade; negative regulation of compound eye photoreceptor development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleoplasm; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of Notch signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of R8 cell spacing in compound eye; regulation of cardioblast cell fate specification; regulation of crystal cell differentiation; regulation of filopodium assembly; regulation of growth; response to symbiont; second mitotic wave involved in compound eye morphogenesis; skeletal muscle tissue development; subapical complex; transcription, DNA-dependent; transmembrane signaling receptor activity; ventral cord development; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTCH_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]" comp144027_c0_seq13,2514,40.5728,0.7079973,0,0,,7.00E-06,Q9UT85,Uncharacterized WD repeat-containing protein C343.04c,Uncharacterized WD repeat-containing protein C343.04c,GO:0034657; GO:0005829; GO:0044732; GO:0045721; GO:0005634; GO:0043161,GID complex; cytosol; mitotic spindle pole body; negative regulation of gluconeogenesis; nucleus; proteasomal ubiquitin-dependent protein catabolic process,PF00400;,,,,,,,,,YIPC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),negative regulation of gluconeogenesis [GO:0045721]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp144027_c0_seq14,2519,40.2541,0.71801048,0,0,,2.00E-26,Q4KLI9,F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),GO:0080008; GO:0019005; GO:0031146; GO:0051298; GO:0005737; GO:0016567,Cul4-RING ubiquitin ligase complex; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication; cytoplasm; protein ubiquitination,PF12937;PF00400;,,,,,,,,,FBXW5_RAT,Rattus norvegicus (Rat),centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp144027_c0_seq15,779,43.5173,0.98915198,0,0,,2.00E-23,Q8BNA6,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_MOUSE,Mus musculus (Mouse),cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842] comp144027_c0_seq2,582,40.0344,0.62688357,19,97,,7.00E-06,A1DHW6,Probable E3 ubiquitin ligase complex SCF subunit sconB (Sulfur controller B) (Sulfur metabolite repression control protein B),Probable E3 ubiquitin ligase complex SCF subunit sconB (Sulfur controller B) (Sulfur metabolite repression control protein B),GO:0016567; GO:0006355; GO:0006351,"protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12937;PF00400;,,,,,,,,,SCONB_NEOFI,Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144027_c0_seq3,1382,38.9291,0.71283732,0,0,,1.00E-27,Q4KLI9,F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5),GO:0080008; GO:0019005; GO:0031146; GO:0051298; GO:0005737; GO:0016567,Cul4-RING ubiquitin ligase complex; SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication; cytoplasm; protein ubiquitination,PF12937;PF00400;,,,,,,,,,FBXW5_RAT,Rattus norvegicus (Rat),centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp144027_c0_seq4,675,46.2222,1.08114715,0,0,,9.00E-20,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp144027_c0_seq5,1053,43.8746,1.16250105,0,0,,2.00E-57,P07207,Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],GO:0005796; GO:0061382; GO:0007219; GO:0048052; GO:0007464; GO:0045466; GO:0045463; GO:0007460; GO:0007015; GO:0005912; GO:0008356; GO:0007298; GO:0005509; GO:0009986; GO:0008407; GO:0003682; GO:0042676; GO:0046667; GO:0005829; GO:0008340; GO:0046843; GO:0007391; GO:0007451; GO:0007398; GO:0035165; GO:0005788; GO:0005768; GO:0061331; GO:0035153; GO:0035214; GO:0007440; GO:0060288; GO:0030718; GO:0030708; GO:0007403; GO:0008347; GO:0035172; GO:0007157; GO:0007446; GO:0016348; GO:0048803; GO:0008587; GO:0007474; GO:0016021; GO:0035171; GO:0046331; GO:0007616; GO:0035170; GO:0007498; GO:0008045; GO:0007521; GO:0046329; GO:0045316; GO:0035157; GO:0050768; GO:0035155; GO:0000122; GO:0007400; GO:0005654; GO:0007314; GO:0030720; GO:0030713; GO:0007422; GO:1900087; GO:0045747; GO:0008284; GO:0045944; GO:0043234; GO:0045468; GO:0042686; GO:0042689; GO:0051489; GO:0040008; GO:0009608; GO:0016330; GO:0007519; GO:0035003; GO:0006351; GO:0004888; GO:0007419; GO:0048190; GO:0007473,"Golgi lumen; Malpighian tubule tip cell differentiation; Notch signaling pathway; R1/R6 cell differentiation; R3/R4 cell fate commitment; R7 cell differentiation; R8 cell development; R8 cell fate commitment; actin filament organization; adherens junction; asymmetric cell division; border follicle cell migration; calcium ion binding; cell surface; chaeta morphogenesis; chromatin binding; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; cytosol; determination of adult lifespan; dorsal appendage formation; dorsal closure; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; embryonic crystal cell differentiation; endoplasmic reticulum lumen; endosome; epithelial cell proliferation involved in Malpighian tubule morphogenesis; epithelial cell type specification, open tracheal system; eye-antennal disc development; foregut morphogenesis; formation of a compartment boundary; germ-line stem cell maintenance; germarium-derived female germ-line cyst encapsulation; glial cell fate determination; glial cell migration; hemocyte proliferation; heterophilic cell-cell adhesion; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived male genitalia morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; lamellocyte differentiation; lateral inhibition; long-term memory; lymph gland crystal cell differentiation; mesoderm development; motor neuron axon guidance; muscle cell fate determination; negative regulation of JNK cascade; negative regulation of compound eye photoreceptor development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleoplasm; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of Notch signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of R8 cell spacing in compound eye; regulation of cardioblast cell fate specification; regulation of crystal cell differentiation; regulation of filopodium assembly; regulation of growth; response to symbiont; second mitotic wave involved in compound eye morphogenesis; skeletal muscle tissue development; subapical complex; transcription, DNA-dependent; transmembrane signaling receptor activity; ventral cord development; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTCH_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]" comp144028_c0_seq1,2395,38.6221,0.59896055,120,438,,,,,,,,,1.00E-108,CHOYP_ZGC_162613.1.1,,,,,,,,, comp144028_c0_seq3,2205,39.1837,0.61896758,25,123,,5.00E-101,Q499P8,UPF0420 protein C16orf58 homolog,RUS1 family protein C16orf58 homolog,GO:0016021,integral to membrane,PF04884;,1.00E-108,CHOYP_ZGC_162613.1.1,,,4.00E-98,CU989217.p.cg.6,4,female gonad,CP058_RAT,Rattus norvegicus (Rat), comp144028_c0_seq4,1300,40.3077,0.32565726,137,448,,0,Q13356,Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Rotamase PPIL2),Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (EC 6.3.2.-) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (Rotamase PPIL2),GO:0005796; GO:0007596; GO:0050900; GO:0005634; GO:0003755; GO:0006457; GO:0000413; GO:0000209; GO:0000151; GO:0034450,Golgi lumen; blood coagulation; leukocyte migration; nucleus; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; protein polyubiquitination; ubiquitin ligase complex; ubiquitin-ubiquitin ligase activity,PF00160;,1.00E-174,CHOYP_PPIL2.1.1,,,,,,,PPIL2_HUMAN,Homo sapiens (Human),leukocyte migration [GO:0050900]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209] comp144029_c0_seq1,1051,40.5328,0.39440756,0,0,,,,,,,,,2.00E-12,CHOYP_LOC100006059.1.1,,,,,,,,, comp144029_c0_seq2,1819,42.1111,0.28586461,10,0,,6.00E-62,Q68DL7,Uncharacterized protein C18orf63,Uncharacterized protein C18orf63,,,PF15813;,,,,,,,,,CR063_HUMAN,Homo sapiens (Human), comp144029_c0_seq5,1087,44.3422,0.33727747,0,0,,6.00E-57,Q68DL7,Uncharacterized protein C18orf63,Uncharacterized protein C18orf63,,,PF15813;,,,,,,,,,CR063_HUMAN,Homo sapiens (Human), comp144029_c0_seq6,814,44.226,0.35233502,6,9,,,,,,,,,7.00E-11,CHOYP_LOC100006059.1.1,,,,,,,,, comp144030_c0_seq1,949,47.313,0.39706278,0,7,,,,,,,,,,,5.00E-49,ruditapes_c13925,,,,,,, comp144030_c0_seq10,1992,45.7329,0.39693693,0,0,,0,Q9ULT8,E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),GO:0005737; GO:0046872; GO:0001843; GO:0005634; GO:0042787; GO:0004842,cytoplasm; metal ion binding; neural tube closure; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12796;PF00632;PF06701;PF07738;,,,,,,,,,HECD1_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144030_c0_seq2,3059,47.0088,0.43464561,16,14,,0,Q69ZR2,E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (HECT domain-containing protein 1) (Protein open mind),E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (HECT domain-containing protein 1) (Protein open mind),GO:0005737; GO:0046872; GO:0001843; GO:0005634; GO:0042787; GO:0004842,cytoplasm; metal ion binding; neural tube closure; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12796;PF00632;PF06701;PF07738;,,,,,,,,,HECD1_MOUSE,Mus musculus (Mouse),aorta development [GO:0035904]; embryonic placenta development [GO:0001892]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] comp144030_c0_seq4,3038,46.9388,0.43237138,5,2,,2.00E-17,Q4U2R1,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0020037; GO:0005743; GO:0005634; GO:0042787; GO:0007283; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; heme binding; mitochondrial inner membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,4.00E-147,CHOYP_HECD1.1.1,,,,,,,HERC2_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp144030_c0_seq6,1991,45.7057,0.38662105,0,0,,2.00E-08,Q3UES3,Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II),Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II),GO:0000139; GO:0003950; GO:0016055; GO:0000781; GO:0046872; GO:0035264; GO:0005635; GO:0000242; GO:0048471; GO:0090263; GO:0070213; GO:0070198; GO:0000209; GO:0040014; GO:0000723,"Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; chromosome, telomeric region; metal ion binding; multicellular organism growth; nuclear envelope; pericentriolar material; perinuclear region of cytoplasm; positive regulation of canonical Wnt receptor signaling pathway; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein polyubiquitination; regulation of multicellular organism growth; telomere maintenance",PF00023;PF12796;PF00644;PF07647;,,,,,,,,,TNKS2_MOUSE,Mus musculus (Mouse),"multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; telomere maintenance [GO:0000723]; Wnt signaling pathway [GO:0016055]" comp144030_c0_seq7,2207,48.029,0.38715226,17,0,,7.00E-18,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp144030_c0_seq9,842,47.2684,0.51721831,27,2,,9.00E-10,Q6WWW4,E3 ubiquitin-protein ligase UPL3 (Ubiquitin-protein ligase 3) (EC 6.3.2.-) (HECT ubiquitin-protein ligase 3) (Protein KAKTUS),E3 ubiquitin-protein ligase UPL3 (Ubiquitin-protein ligase 3) (EC 6.3.2.-) (HECT ubiquitin-protein ligase 3) (Protein KAKTUS),GO:0042023; GO:0005886; GO:0042787; GO:0010091; GO:0004842,DNA endoreduplication; plasma membrane; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; trichome branching; ubiquitin-protein ligase activity,PF00632;,6.00E-101,CHOYP_HECD1.1.1,,,,,,,UPL3_ARATH,Arabidopsis thaliana (Mouse-ear cress),DNA endoreduplication [GO:0042023]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; trichome branching [GO:0010091] comp144032_c3_seq1,2339,43.3091,0.52600454,687,2969,,6.00E-23,Q57984,Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),GO:0005524; GO:0004813; GO:0006419; GO:0002161; GO:0005737; GO:0046872; GO:0000049,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; aminoacyl-tRNA editing activity; cytoplasm; metal ion binding; tRNA binding,PF01411;PF07973;,,,,,,,,,SYA_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),alanyl-tRNA aminoacylation [GO:0006419] comp144032_c3_seq2,1193,46.3537,0.59251651,162,410,,0,Q9VLM8,"Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)","Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)",GO:0005524; GO:0004813; GO:0006419; GO:0005737; GO:0046872; GO:0000049,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytoplasm; metal ion binding; tRNA binding,PF02272;PF01411;PF07973;,1.00E-154,CHOYP_SYAC.2.2,,,,,,,SYAC_DROME,Drosophila melanogaster (Fruit fly),alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400] comp144033_c0_seq1,604,36.0927,1.52765338,5,0,,1.00E-11,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp144033_c0_seq3,1133,41.1297,1.21171797,24,4,,2.00E-38,Q7JQ07,Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),GO:0003677; GO:0015074; GO:0006310; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA integration; DNA recombination; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF01359;,,,,,,,,,MOS1T_DROMA,Drosophila mauritiana (Fruit fly),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp144033_c0_seq4,615,36.0976,1.5500041,14,0,,4.00E-13,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp144033_c0_seq7,1338,37.7429,1.32374615,22,10,,6.00E-15,Q7JQ07,Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),GO:0003677; GO:0015074; GO:0006310; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA integration; DNA recombination; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF01359;,,,,,,,,,MOS1T_DROMA,Drosophila mauritiana (Fruit fly),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp144033_c0_seq8,670,37.9104,0.84546273,34,8,,6.00E-09,P20849,Collagen alpha-1(IX) chain,Collagen alpha-1(IX) chain,GO:0007411; GO:0030574; GO:0005594; GO:0005788; GO:0022617; GO:0030020; GO:0003417; GO:0046872; GO:0009887; GO:0001894,axon guidance; collagen catabolic process; collagen type IX; endoplasmic reticulum lumen; extracellular matrix disassembly; extracellular matrix structural constituent conferring tensile strength; growth plate cartilage development; metal ion binding; organ morphogenesis; tissue homeostasis,PF01391;,,,,,,,,,CO9A1_HUMAN,Homo sapiens (Human),chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]; organ morphogenesis [GO:0009887] comp144035_c0_seq5,1497,47.3614,0.35904909,191,318,,4.00E-81,P0CB49,YLP motif-containing protein 1 (Nuclear protein ZAP3),YLP motif-containing protein 1 (Nuclear protein ZAP3),GO:0016607; GO:0006355; GO:0006351,"nuclear speck; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,4.00E-80,CHOYP_YLPM1.1.2,,,,,,,YLPM1_RAT,Rattus norvegicus (Rat),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144037_c1_seq10,2867,42.6578,0.47930702,0,0,,8.00E-72,Q8TC92,Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)],Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)],GO:0005615; GO:0003676; GO:0000166; GO:0016491; GO:0005886; GO:0048511,extracellular space; nucleic acid binding; nucleotide binding; oxidoreductase activity; plasma membrane; rhythmic process,PF00076;,,,,,,,,,ENOX1_HUMAN,Homo sapiens (Human),rhythmic process [GO:0048511] comp144037_c1_seq2,2820,42.695,0.49415726,0,0,,,,,,,,,4.00E-83,CHOYP_LOC660510.1.1,,,,,,,,, comp144037_c1_seq5,2927,42.6717,0.50762835,0,0,,2.00E-129,Q16206,Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)],Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)],GO:0016049; GO:0005829; GO:0009897; GO:0005615; GO:0003676; GO:0000166; GO:0015035; GO:0040008; GO:0007624,cell growth; cytosol; external side of plasma membrane; extracellular space; nucleic acid binding; nucleotide binding; protein disulfide oxidoreductase activity; regulation of growth; ultradian rhythm,PF00076;,,,,,,,,,ENOX2_HUMAN,Homo sapiens (Human),cell growth [GO:0016049]; oxidation-reduction process [GO:0055114]; regulation of growth [GO:0040008]; ultradian rhythm [GO:0007624] comp144037_c1_seq6,2974,42.6698,0.4997608,0,0,,,,,,,,,2.00E-125,CHOYP_ENOX2.1.1,,,,,,,,, comp144037_c1_seq7,2941,42.6386,0.49786001,0,0,,2.00E-129,Q16206,Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)],Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)],GO:0016049; GO:0005829; GO:0009897; GO:0005615; GO:0003676; GO:0000166; GO:0015035; GO:0040008; GO:0007624,cell growth; cytosol; external side of plasma membrane; extracellular space; nucleic acid binding; nucleotide binding; protein disulfide oxidoreductase activity; regulation of growth; ultradian rhythm,PF00076;,,,,,,,,,ENOX2_HUMAN,Homo sapiens (Human),cell growth [GO:0016049]; oxidation-reduction process [GO:0055114]; regulation of growth [GO:0040008]; ultradian rhythm [GO:0007624] comp144037_c1_seq8,2960,42.7365,0.49330274,0,0,,,,,,,,,3.00E-124,CHOYP_ENOX2.1.1,,,,,,,,, comp144037_c1_seq9,2834,42.6253,0.4850436,0,0,,,,,,,,,2.00E-81,CHOYP_LOC660510.1.1,,,,,,,,, comp144039_c0_seq1,4132,43.1752,0.5694025,748,158,,2.00E-124,Q64702,Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak),Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak),GO:0005524; GO:0005814; GO:0007099; GO:0032154; GO:0005730; GO:0018108; GO:0046601; GO:0004674; GO:0004713; GO:0060707,ATP binding; centriole; centriole replication; cleavage furrow; nucleolus; peptidyl-tyrosine phosphorylation; positive regulation of centriole replication; protein serine/threonine kinase activity; protein tyrosine kinase activity; trophoblast giant cell differentiation,PF00069;PF00659;,3.00E-113,CHOYP_PLK4.1.1,,,,,,,PLK4_MOUSE,Mus musculus (Mouse),centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; positive regulation of centriole replication [GO:0046601]; trophoblast giant cell differentiation [GO:0060707] comp144039_c0_seq2,546,44.3223,0.57309684,10,0,,1.00E-48,Q6PAD2,Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak),Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak),GO:0005524; GO:0005814; GO:0007099; GO:0005730; GO:0018108; GO:0046601; GO:0004674; GO:0004713,ATP binding; centriole; centriole replication; nucleolus; peptidyl-tyrosine phosphorylation; positive regulation of centriole replication; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;PF00659;,5.00E-61,CHOYP_PLK4.1.1,,,,,,,PLK4_XENLA,Xenopus laevis (African clawed frog),centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; positive regulation of centriole replication [GO:0046601] comp144040_c0_seq1,1604,39.1521,0.40706715,946,2097,,9.00E-79,Q9Y3A0,"Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog)","Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog)",GO:0005743; GO:0005739; GO:0006744,mitochondrial inner membrane; mitochondrion; ubiquinone biosynthetic process,PF05019;,1.00E-61,CHOYP_COQ4.1.1,,,,,,,COQ4_HUMAN,Homo sapiens (Human),ubiquinone biosynthetic process [GO:0006744] comp144040_c0_seq3,1991,43.1944,0.55499301,118,658,,2.00E-172,Q12788,Transducin beta-like protein 3 (WD repeat-containing protein SAZD),Transducin beta-like protein 3 (WD repeat-containing protein SAZD),GO:0007199; GO:0005730; GO:0006364; GO:0005057; GO:0032040,G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; nucleolus; rRNA processing; receptor signaling protein activity; small-subunit processome,PF08625;PF00400;,3.00E-71,CHOYP_LOC100707920.1.1,,,,,,,TBL3_HUMAN,Homo sapiens (Human),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]" comp144040_c1_seq1,1022,42.0744,0.35582643,48,136,,4.00E-17,C4YFX2,Transcriptional repressor TUP1,Transcriptional repressor TUP1,GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP1_CANAW,Candida albicans (strain WO-1) (Yeast),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144041_c0_seq1,2897,39.1785,0.41411048,42,181,,2.00E-65,Q8IWZ8,SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4),SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4),GO:0003723; GO:0000398; GO:0005654; GO:0005681,"RNA binding; mRNA splicing, via spliceosome; nucleoplasm; spliceosomal complex",PF01585;PF01805;,4.00E-96,CHOYP_A4.3.3,4.00E-69,ruditapes_c30671,,,,,SUGP1_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]" comp144043_c0_seq1,3609,42.4217,1.00439022,666,1994,,0,Q16706,"Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0006491; GO:0030246; GO:0016799; GO:0001701; GO:0016021; GO:0001889; GO:0048286; GO:0006013; GO:0004572; GO:0007005; GO:0043687; GO:0018279; GO:0007585; GO:0007033; GO:0008270,"Golgi membrane; N-glycan processing; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; in utero embryonic development; integral to membrane; liver development; lung alveolus development; mannose metabolic process; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; mitochondrion organization; post-translational protein modification; protein N-linked glycosylation via asparagine; respiratory gaseous exchange; vacuole organization; zinc ion binding",PF09261;PF01074;PF07748;,4.00E-15,CHOYP_NEMVEDRAFT_V1G166900.1.1,,,,,,,MA2A1_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033] comp144046_c0_seq1,8888,44.3519,0.41305763,485,176,,0,Q70CQ2,Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),GO:0016055; GO:0004197; GO:0090263; GO:0071108; GO:0004221; GO:0006511; GO:0004843,Wnt receptor signaling pathway; cysteine-type endopeptidase activity; positive regulation of canonical Wnt receptor signaling pathway; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,0,CHOYP_UBP34.1.1,,,,,,,UBP34_HUMAN,Homo sapiens (Human),"histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]" comp144046_c0_seq3,5890,44.7538,0.41571272,29,0,,0,Q70CQ2,Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34),GO:0016055; GO:0004197; GO:0090263; GO:0071108; GO:0004221; GO:0006511; GO:0004843,Wnt receptor signaling pathway; cysteine-type endopeptidase activity; positive regulation of canonical Wnt receptor signaling pathway; protein K48-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,0,CHOYP_UBP34.1.1,,,,,,,UBP34_HUMAN,Homo sapiens (Human),"histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]" comp144047_c0_seq1,2686,39.6873,0.47307534,1266,27,,0,Q9BX10,GTP-binding protein 2,GTP-binding protein 2,GO:0005525; GO:0006184; GO:0003924,GTP binding; GTP catabolic process; GTPase activity,,3.00E-136,CHOYP_LOC100375058.1.1,,,,,,,GTPB2_HUMAN,Homo sapiens (Human),translational elongation [GO:0006414] comp144048_c0_seq2,3382,42.3418,0.34322732,0,0,,2.00E-07,A9CPT4,Tudor domain-containing protein 1,Tudor domain-containing protein 1,GO:0043046; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,5.00E-11,ruditapes_c15991,,,,,TDRD1_ORYLA,Oryzias latipes (Japanese rice fish) (Japanese killifish),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp144048_c0_seq5,6173,40.4503,0.35663811,271,338,,4.00E-08,E2QTD3,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp144049_c0_seq3,4698,42.55,0.44001354,206,1052,,9.00E-29,Q6TQE1,Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1),Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1),GO:0046872; GO:0005634,metal ion binding; nucleus,,7.00E-26,CHOYP_ZC3H18.1.1,,,,,,,ZCH18_RAT,Rattus norvegicus (Rat), comp144050_c0_seq1,3179,39.4464,0.51304609,1411,5032,,1.00E-90,Q8CAQ8,Mitochondrial inner membrane protein (Mitofilin),MICOS complex subunit Mic60 (Mitochondrial inner membrane protein) (Mitofilin),GO:0016021; GO:0051560; GO:0005743,integral to membrane; mitochondrial calcium ion homeostasis; mitochondrial inner membrane,PF09731;,,,,,,,,,IMMT_MOUSE,Mus musculus (Mouse),cristae formation [GO:0042407]; mitochondrial calcium ion homeostasis [GO:0051560] comp144051_c0_seq1,4067,37.8166,0.48304363,0,0,,0,Q5ZLF4,Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5),Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5),GO:0005794; GO:0016324; GO:0006882; GO:0006824; GO:0016021; GO:0005730; GO:0010043; GO:0030141; GO:0005385,Golgi apparatus; apical plasma membrane; cellular zinc ion homeostasis; cobalt ion transport; integral to membrane; nucleolus; response to zinc ion; secretory granule; zinc ion transmembrane transporter activity,PF01545;,2.00E-127,CHOYP_ZNT5.1.1,,,,,,,ZNT5_CHICK,Gallus gallus (Chicken),cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp144051_c0_seq2,4128,38.0814,0.48308488,0,0,,0,Q8TAD4,Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1),Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1),GO:0000139; GO:0016324; GO:0044267; GO:0006882; GO:0006824; GO:0005887; GO:0005730; GO:0010155; GO:0010043; GO:0030667; GO:0008270; GO:0005385,Golgi membrane; apical plasma membrane; cellular protein metabolic process; cellular zinc ion homeostasis; cobalt ion transport; integral to plasma membrane; nucleolus; regulation of proton transport; response to zinc ion; secretory granule membrane; zinc ion binding; zinc ion transmembrane transporter activity,PF01545;,4.00E-16,CHOYP_BRAFLDRAFT_276675.1.1,,,,,,,ZNT5_HUMAN,Homo sapiens (Human),cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of proton transport [GO:0010155]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829] comp144051_c0_seq3,4080,37.8431,0.48095915,0,0,,4.00E-74,Q8H329,Metal tolerance protein 8 (OsMTP8),Metal tolerance protein 8 (OsMTP8),GO:0008324; GO:0016021; GO:0005774,cation transmembrane transporter activity; integral to membrane; vacuolar membrane,PF01545;,,,,,,,,,MTP8_ORYSJ,Oryza sativa subsp. japonica (Rice),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp144051_c0_seq4,4126,38.1483,0.49484415,0,0,,,,,,,,,4.00E-161,CHOYP_ZNT5.1.1,,,,,,,,, comp144051_c0_seq5,4078,37.9107,0.49302984,0,0,,6.00E-65,Q9SI03,Metal tolerance protein 12 (AtMTP12),Metal tolerance protein 12 (AtMTP12),GO:0008324; GO:0016021; GO:0005774,cation transmembrane transporter activity; integral to membrane; vacuolar membrane,PF01545;,,,,,,,,,MTP12_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp144051_c0_seq6,4092,37.8299,0.49351244,0,0,,0,Q5ZLF4,Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5),Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5),GO:0005794; GO:0016324; GO:0006882; GO:0006824; GO:0016021; GO:0005730; GO:0010043; GO:0030141; GO:0005385,Golgi apparatus; apical plasma membrane; cellular zinc ion homeostasis; cobalt ion transport; integral to membrane; nucleolus; response to zinc ion; secretory granule; zinc ion transmembrane transporter activity,PF01545;,,,,,,,,,ZNT5_CHICK,Gallus gallus (Chicken),cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp144051_c0_seq7,4140,38.0676,0.49533496,0,0,,3.00E-66,Q54F34,Probable zinc transporter protein DDB_G0291141,Probable zinc transporter protein DDB_G0291141,GO:0016021; GO:0046872; GO:0005385,integral to membrane; metal ion binding; zinc ion transmembrane transporter activity,PF01545;,4.00E-161,CHOYP_ZNT5.1.1,,,,,,,Y1141_DICDI,Dictyostelium discoideum (Slime mold),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829] comp144051_c0_seq8,4115,38.0559,0.48512313,0,0,,0,Q8TAD4,Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1),Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1),GO:0000139; GO:0016324; GO:0044267; GO:0006882; GO:0006824; GO:0005887; GO:0005730; GO:0010155; GO:0010043; GO:0030667; GO:0008270; GO:0005385,Golgi membrane; apical plasma membrane; cellular protein metabolic process; cellular zinc ion homeostasis; cobalt ion transport; integral to plasma membrane; nucleolus; regulation of proton transport; response to zinc ion; secretory granule membrane; zinc ion binding; zinc ion transmembrane transporter activity,PF01545;,4.00E-161,CHOYP_ZNT5.1.1,,,,,,,ZNT5_HUMAN,Homo sapiens (Human),cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of proton transport [GO:0010155]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829] comp144052_c0_seq2,6661,40.5194,0.39995484,492,440,,2.00E-52,O88196,E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (TPR repeat protein D) (Mtprd),E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (TPR repeat protein D) (Mtprd),GO:0010771; GO:0045665; GO:0005634; GO:0070936; GO:0006511; GO:0004842; GO:0005773; GO:0008270,negative regulation of cell morphogenesis involved in differentiation; negative regulation of neuron differentiation; nucleus; protein K48-linked ubiquitination; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; vacuole; zinc ion binding,PF13639;,7.00E-22,CHOYP_LOC100366748.1.1,,,,,,,TTC3_MOUSE,Mus musculus (Mouse),negative regulation of cell morphogenesis involved in differentiation [GO:0010771]; negative regulation of neuron differentiation [GO:0045665]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144054_c2_seq1,4759,52.6581,0.66327429,69,59,,0,Q8CJ40,Rootletin (Ciliary rootlet coiled-coil protein),Rootletin (Ciliary rootlet coiled-coil protein),GO:0015629; GO:0007049; GO:0030030; GO:0005814; GO:0051297; GO:0035253; GO:0005886; GO:0008104; GO:0005198,actin cytoskeleton; cell cycle; cell projection organization; centriole; centrosome organization; ciliary rootlet; plasma membrane; protein localization; structural molecule activity,,0,CHOYP_contig_043818,,,,,,,CROCC_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; centriole-centriole cohesion [GO:0010457]; centrosome organization [GO:0051297]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] comp144054_c2_seq2,4340,52.3733,0.6495044,0,0,,0,Q8CJ40,Rootletin (Ciliary rootlet coiled-coil protein),Rootletin (Ciliary rootlet coiled-coil protein),GO:0015629; GO:0007049; GO:0030030; GO:0005814; GO:0051297; GO:0035253; GO:0005886; GO:0008104; GO:0005198,actin cytoskeleton; cell cycle; cell projection organization; centriole; centrosome organization; ciliary rootlet; plasma membrane; protein localization; structural molecule activity,,1.00E-180,CHOYP_contig_043818,,,,,,,CROCC_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; centriole-centriole cohesion [GO:0010457]; centrosome organization [GO:0051297]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] comp144054_c2_seq3,4037,52.539,0.63922579,7,0,,5.00E-15,P21249,Major antigen (Myosin-like antigen),Major antigen (Myosin-like antigen),,,,,,,,,,,,ANT1_ONCVO,Onchocerca volvulus, comp144054_c3_seq1,513,51.462,0.67989676,25,0,,,,,,,,,2.00E-46,CHOYP_contig_043818,,,,,,,,, comp144054_c4_seq2,468,48.2906,0.88400624,14,0,,2.00E-16,Q5TZA2,Rootletin (Ciliary rootlet coiled-coil protein),Rootletin (Ciliary rootlet coiled-coil protein),GO:0015629; GO:0007049; GO:0030030; GO:0005814; GO:0051297; GO:0035253; GO:0019894; GO:0005886; GO:0008104; GO:0005198,actin cytoskeleton; cell cycle; cell projection organization; centriole; centrosome organization; ciliary rootlet; kinesin binding; plasma membrane; protein localization; structural molecule activity,,,,,,,,,,CROCC_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; centriole-centriole cohesion [GO:0010457]; centrosome organization [GO:0051297]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] comp144058_c0_seq1,7841,41.0407,0.54491158,0,0,,0,Q9NSI6,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,3.00E-135,CHOYP_BRWD1.1.1,,,,,,,BRWD1_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq10,4392,39.4126,0.61790565,0,0,,4.00E-12,Q6JHU9,CREB-binding protein (EC 2.3.1.48),CREB-binding protein (EC 2.3.1.48),GO:0043426; GO:0008283; GO:0005737; GO:0004402; GO:0000123; GO:0005634; GO:0042975; GO:0045944; GO:0003713; GO:0005667; GO:0006351; GO:0008270,"MRF binding; cell proliferation; cytoplasm; histone acetyltransferase activity; histone acetyltransferase complex; nucleus; peroxisome proliferator activated receptor binding; positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor complex; transcription, DNA-dependent; zinc ion binding",PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;,,,,,,,,,CBP_RAT,Rattus norvegicus (Rat),"cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular response to UV [GO:0034644]; histone acetylation [GO:0016573]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq11,5992,45.9112,0.54769498,0,0,,0,Q9NSI6,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,2.00E-135,CHOYP_BRWD1.1.1,,,,,,,BRWD1_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq12,3490,44.2407,0.60987583,0,0,,1.00E-12,Q92793,CREB-binding protein (EC 2.3.1.48),CREB-binding protein (EC 2.3.1.48),GO:0043426; GO:0018076; GO:0007219; GO:0001102; GO:0001078; GO:0001105; GO:0001191; GO:0044255; GO:0003682; GO:0000940; GO:0000987; GO:0005737; GO:0042733; GO:0030718; GO:0004402; GO:0000123; GO:0042592; GO:0045087; GO:0019048; GO:0016604; GO:0000790; GO:0032481; GO:0006461; GO:0008589; GO:0061418; GO:0004871; GO:0044281; GO:0005667; GO:0006367; GO:0008270,MRF binding; N-terminal peptidyl-lysine acetylation; Notch signaling pathway; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II transcription coactivator activity; RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; cellular lipid metabolic process; chromatin binding; condensed chromosome outer kinetochore; core promoter proximal region sequence-specific DNA binding; cytoplasm; embryonic digit morphogenesis; germ-line stem cell maintenance; histone acetyltransferase activity; histone acetyltransferase complex; homeostatic process; innate immune response; modulation by virus of host morphology or physiology; nuclear body; nuclear chromatin; positive regulation of type I interferon production; protein complex assembly; regulation of smoothened signaling pathway; regulation of transcription from RNA polymerase II promoter in response to hypoxia; signal transducer activity; small molecule metabolic process; transcription factor complex; transcription initiation from RNA polymerase II promoter; zinc ion binding,PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;,,,,,,,,,CBP_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular lipid metabolic process [GO:0044255]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein complex assembly [GO:0006461]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp144058_c0_seq15,7735,41.1118,0.53823723,0,0,,0,Q9NSI6,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,3.00E-135,CHOYP_BRWD1.1.1,,,,,,,BRWD1_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq17,4498,39.2841,0.62448016,0,0,,2.00E-07,Q92831,Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF),Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF),GO:0031672; GO:0005671; GO:0031674; GO:0018076; GO:0007219; GO:0000125; GO:0042641; GO:0007050; GO:0032869; GO:0006338; GO:0004861; GO:0043966; GO:0004402; GO:0000776; GO:0004468; GO:0019048; GO:0008285; GO:0045736; GO:0045944; GO:0032403; GO:0019901; GO:0010835; GO:0003713; GO:0006361; GO:0006367,A band; Ada2/Gcn5/Ada3 transcription activator complex; I band; N-terminal peptidyl-lysine acetylation; Notch signaling pathway; PCAF complex; actomyosin; cell cycle arrest; cellular response to insulin stimulus; chromatin remodeling; cyclin-dependent protein serine/threonine kinase inhibitor activity; histone H3 acetylation; histone acetyltransferase activity; kinetochore; lysine N-acetyltransferase activity; modulation by virus of host morphology or physiology; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; positive regulation of transcription from RNA polymerase II promoter; protein complex binding; protein kinase binding; regulation of protein ADP-ribosylation; transcription coactivator activity; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter,PF00583;PF00439;PF06466;,,,,,,,,,KAT2B_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to parathyroid hormone stimulus [GO:0071374]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; memory [GO:0007613]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of chromatin binding [GO:0035563]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vasodilation [GO:0045909]; protein acetylation [GO:0006473]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp144058_c0_seq18,3384,44.5626,0.60218892,0,0,,7.00E-156,Q8WWQ0,PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11),PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11),GO:0007010; GO:0070577; GO:0005158; GO:0008286; GO:0043066; GO:2001237; GO:0005634; GO:0008284; GO:0043568; GO:0045840; GO:0033138; GO:0010800; GO:0045944; GO:0006606; GO:0022604; GO:0040008; GO:0001932,cytoskeleton organization; histone acetyl-lysine binding; insulin receptor binding; insulin receptor signaling pathway; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; nucleus; positive regulation of cell proliferation; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of mitosis; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein import into nucleus; regulation of cell morphogenesis; regulation of growth; regulation of protein phosphorylation,PF00439;PF00400;,,,,,,,,,PHIP_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]" comp144058_c0_seq19,3408,44.6596,0.60747703,0,0,,3.00E-153,Q8WWQ0,PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11),PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11),GO:0007010; GO:0070577; GO:0005158; GO:0008286; GO:0043066; GO:2001237; GO:0005634; GO:0008284; GO:0043568; GO:0045840; GO:0033138; GO:0010800; GO:0045944; GO:0006606; GO:0022604; GO:0040008; GO:0001932,cytoskeleton organization; histone acetyl-lysine binding; insulin receptor binding; insulin receptor signaling pathway; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; nucleus; positive regulation of cell proliferation; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of mitosis; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein import into nucleus; regulation of cell morphogenesis; regulation of growth; regulation of protein phosphorylation,PF00439;PF00400;,2.00E-44,CHOYP_BRWD1.1.1,,,,,,,PHIP_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]" comp144058_c0_seq2,4416,39.5607,0.6277298,0,0,,2.00E-11,Q55C84,Bromodomain-containing protein DDB_G0270170,Bromodomain-containing protein DDB_G0270170,,,PF17035;PF00439;,,,,,,,,,Y0170_DICDI,Dictyostelium discoideum (Slime mold), comp144058_c0_seq3,7865,41.0935,0.54803302,0,0,,0,Q9NSI6,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,3.00E-135,CHOYP_BRWD1.1.1,,,,,,,BRWD1_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq4,5968,45.8277,0.542123,0,0,,0,Q9NSI6,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,2.00E-135,CHOYP_BRWD1.1.1,,,,,,,BRWD1_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq5,3513,44.3496,0.61483016,96,0,,1.00E-07,Q58F21,Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein),Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein),GO:0008380; GO:0030154; GO:0006338; GO:0070577; GO:0001207; GO:0006397; GO:0007141; GO:0005634; GO:0051039; GO:0043484; GO:0007283; GO:0003713; GO:0006351,"RNA splicing; cell differentiation; chromatin remodeling; histone acetyl-lysine binding; histone displacement; mRNA processing; male meiosis I; nucleus; positive regulation of transcription during meiosis; regulation of RNA splicing; spermatogenesis; transcription coactivator activity; transcription, DNA-dependent",PF17035;PF17105;PF00439;,,,,,,,,,BRDT_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; chromatin remodeling [GO:0006338]; histone displacement [GO:0001207]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; mRNA processing [GO:0006397]; positive regulation of transcription involved in meiotic cell cycle [GO:0051039]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq6,6074,45.6207,0.54695037,0,0,,0,A2AHJ4,Bromodomain and WD repeat-containing protein 3,Bromodomain and WD repeat-containing protein 3,GO:0007010; GO:0008360,cytoskeleton organization; regulation of cell shape,PF00439;PF00400;,,,,,,,,,BRWD3_MOUSE,Mus musculus (Mouse),cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp144058_c0_seq8,6098,45.7035,0.55244509,0,0,,0,Q9NSI6,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,,,,,,,,,BRWD1_HUMAN,Homo sapiens (Human),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144058_c0_seq9,7759,41.1651,0.54142684,0,0,,0,Q921C3,Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9),GO:0005737; GO:0007010; GO:0005730; GO:0005634; GO:0008360; GO:0006357; GO:0006351,"cytoplasm; cytoskeleton organization; nucleolus; nucleus; regulation of cell shape; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00439;PF00400;,3.00E-135,CHOYP_BRWD1.1.1,,,,,,,BRWD1_MOUSE,Mus musculus (Mouse),"cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144059_c0_seq3,1277,30.6969,0.50058785,3,29,,,,,,,,,,,2.00E-11,ruditapes_c17176,,,,,,, comp144062_c0_seq1,1849,43.1585,0.5345479,1244,44,,5.00E-81,Q4G0U5,Primary ciliary dyskinesia protein 1,Cilia- and flagella-associated protein 221 (Primary ciliary dyskinesia protein 1),GO:0005929; GO:0060271; GO:0003341,cilium; cilium morphogenesis; cilium movement,,2.00E-111,CHOYP_LOC100367352.1.1,,,,,,,PCDP1_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; cilium movement [GO:0003341] comp144063_c0_seq1,4218,39.1181,1.14946437,0,194,,2.00E-77,Q24524,Protein singed,Protein singed,GO:0015629; GO:0051015; GO:0048800; GO:0008407; GO:0035017; GO:0005737; GO:0016358; GO:0007163; GO:0046847; GO:0035099; GO:0035317; GO:0030034; GO:0043005; GO:0048812; GO:0043025; GO:0048477; GO:0042060,actin cytoskeleton; actin filament binding; antennal morphogenesis; chaeta morphogenesis; cuticle pattern formation; cytoplasm; dendrite development; establishment or maintenance of cell polarity; filopodium assembly; hemocyte migration; imaginal disc-derived wing hair organization; microvillar actin bundle assembly; neuron projection; neuron projection morphogenesis; neuronal cell body; oogenesis; wound healing,PF06268;,,,,,,,,,SING_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060] comp144063_c0_seq3,4274,39.0501,1.14464758,10,354,,2.00E-77,Q24524,Protein singed,Protein singed,GO:0015629; GO:0051015; GO:0048800; GO:0008407; GO:0035017; GO:0005737; GO:0016358; GO:0007163; GO:0046847; GO:0035099; GO:0035317; GO:0030034; GO:0043005; GO:0048812; GO:0043025; GO:0048477; GO:0042060,actin cytoskeleton; actin filament binding; antennal morphogenesis; chaeta morphogenesis; cuticle pattern formation; cytoplasm; dendrite development; establishment or maintenance of cell polarity; filopodium assembly; hemocyte migration; imaginal disc-derived wing hair organization; microvillar actin bundle assembly; neuron projection; neuron projection morphogenesis; neuronal cell body; oogenesis; wound healing,PF06268;,,,,,,,,,SING_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060] comp144064_c0_seq1,4375,45.0514,0.4377578,0,0,,0,Q7Z4L5,Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),GO:0035085; GO:0060271; GO:0005856; GO:0042073; GO:0030991; GO:0007224,cilium axoneme; cilium morphogenesis; cytoskeleton; intraflagellar transport; intraflagellar transport particle A; smoothened signaling pathway,PF13181;,0,CHOYP_BRAFLDRAFT_128460.1.2,,,,,,,TT21B_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591] comp144064_c0_seq3,4357,45.1228,0.44271922,10,24,,0,Q7Z4L5,Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),GO:0035085; GO:0060271; GO:0005856; GO:0042073; GO:0030991; GO:0007224,cilium axoneme; cilium morphogenesis; cytoskeleton; intraflagellar transport; intraflagellar transport particle A; smoothened signaling pathway,PF13181;,,,,,,,,,TT21B_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591] comp144064_c0_seq4,4389,44.9761,0.4424185,0,0,,,,,,,,,0,CHOYP_BRAFLDRAFT_128460.1.2,,,,,,,,, comp144064_c0_seq6,4372,44.968,0.43976223,0,0,,0,Q7Z4L5,Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),GO:0035085; GO:0060271; GO:0005856; GO:0042073; GO:0030991; GO:0007224,cilium axoneme; cilium morphogenesis; cytoskeleton; intraflagellar transport; intraflagellar transport particle A; smoothened signaling pathway,PF13181;,0,CHOYP_BRAFLDRAFT_128460.1.2,,,,,,,TT21B_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591] comp144064_c0_seq9,4431,45.0237,0.44184024,0,0,,0,Q7Z4L5,Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),Tetratricopeptide repeat protein 21B (TPR repeat protein 21B),GO:0035085; GO:0060271; GO:0005856; GO:0042073; GO:0030991; GO:0007224,cilium axoneme; cilium morphogenesis; cytoskeleton; intraflagellar transport; intraflagellar transport particle A; smoothened signaling pathway,PF13181;,0,CHOYP_BRAFLDRAFT_128460.1.2,,,,,,,TT21B_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591] comp144065_c0_seq4,809,43.5105,0.52468016,13,120,,3.00E-55,Q99575,Ribonucleases P/MRP protein subunit POP1 (hPOP1) (EC 3.1.26.5),Ribonucleases P/MRP protein subunit POP1 (hPOP1) (EC 3.1.26.5),GO:0005655; GO:0000171; GO:0000172; GO:0004526; GO:0001682; GO:0016078,nucleolar ribonuclease P complex; ribonuclease MRP activity; ribonuclease MRP complex; ribonuclease P activity; tRNA 5'-leader removal; tRNA catabolic process,PF06978;PF08170;,5.00E-13,CHOYP_LOC100369630.1.1,,,,,,,POP1_HUMAN,Homo sapiens (Human),tRNA 5'-leader removal [GO:0001682]; tRNA catabolic process [GO:0016078]; tRNA processing [GO:0008033] comp144066_c2_seq1,5128,47.3479,0.58482665,0,0,,3.00E-13,Q9WVQ0,Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein),Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein),GO:0005737,cytoplasm,,0,CHOYP_LOC100377856.2.2,,,,,,,PMFBP_MOUSE,Mus musculus (Mouse), comp144066_c2_seq5,5590,46.3864,0.61276548,0,0,,3.00E-13,Q9WVQ0,Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein),Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein),GO:0005737,cytoplasm,,0,CHOYP_LOC100377856.2.2,,,,,,,PMFBP_MOUSE,Mus musculus (Mouse), comp144066_c2_seq6,5107,47.3859,0.58269747,0,0,,3.00E-13,Q9WVQ0,Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein),Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein),GO:0005737,cytoplasm,,,,,,,,,,PMFBP_MOUSE,Mus musculus (Mouse), comp144066_c2_seq7,1171,47.2246,0.57206976,0,0,,,,,,,,,2.00E-57,CHOYP_LOC100377856.1.2,,,,,,,,, comp144067_c0_seq1,2778,37.077,0.37795816,55,163,,4.00E-115,Q8BKZ9,"Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X)","Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X)",GO:0005759; GO:0005739; GO:0016746,"mitochondrial matrix; mitochondrion; transferase activity, transferring acyl groups",PF00198;PF00364;PF02817;,3.00E-35,CHOYP_ODPX.1.1,,,,,,,ODPX_MOUSE,Mus musculus (Mouse),mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732] comp144067_c0_seq2,2784,36.5302,0.35606916,72,172,,6.00E-105,O00330,"Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)","Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)",GO:0005759; GO:0006090; GO:0010510; GO:0016746,"mitochondrial matrix; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; transferase activity, transferring acyl groups",PF00198;PF00364;PF02817;,,,,,,,,,ODPX_HUMAN,Homo sapiens (Human),glyoxylate metabolic process [GO:0046487]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510] comp144068_c0_seq1,1036,35.1351,0.77234431,67,15,,4.00E-30,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,9.00E-11,CHOYP_RTJK.3.3,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144069_c0_seq1,4402,41.5039,0.54943333,6,20,,5.00E-36,Q80Y19,Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A),Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A),GO:0005096; GO:0005622; GO:0043547; GO:0007165,GTPase activator activity; intracellular; positive regulation of GTPase activity; signal transduction,PF00620;,2.00E-58,CHOYP_ARHGAP11A.1.1,,,,,,,RHGBA_MOUSE,Mus musculus (Mouse),signal transduction [GO:0007165] comp144069_c0_seq2,4133,41.4953,0.511908,3,0,,2.00E-19,Q63744,Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) (p122-RhoGAP),Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) (p122-RhoGAP),GO:0005100; GO:0007266; GO:0007202; GO:0032869; GO:0005737; GO:0007010; GO:0005925; GO:0008289; GO:0045121; GO:0008285,Rho GTPase activator activity; Rho protein signal transduction; activation of phospholipase C activity; cellular response to insulin stimulus; cytoplasm; cytoskeleton organization; focal adhesion; lipid binding; membrane raft; negative regulation of cell proliferation,PF00620;PF07647;PF01852;,,,,,,,,,RHG07_RAT,Rattus norvegicus (Rat),activation of phospholipase C activity [GO:0007202]; cellular response to insulin stimulus [GO:0032869]; cytoskeleton organization [GO:0007010]; negative regulation of cell proliferation [GO:0008285]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] comp144069_c0_seq5,4198,41.8533,0.52272288,4,0,,4.00E-36,Q80Y19,Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A),Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A),GO:0005096; GO:0005622; GO:0043547; GO:0007165,GTPase activator activity; intracellular; positive regulation of GTPase activity; signal transduction,PF00620;,2.00E-58,CHOYP_ARHGAP11A.1.1,,,,,,,RHGBA_MOUSE,Mus musculus (Mouse),signal transduction [GO:0007165] comp144071_c0_seq1,3115,35.8909,0.42306167,3,30,,4.00E-11,A5UEV6,1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS),1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS),GO:0052865; GO:0008661; GO:0000287; GO:0016114; GO:0009228; GO:0030976,1-deoxy-D-xylulose 5-phosphate biosynthetic process; 1-deoxy-D-xylulose-5-phosphate synthase activity; magnesium ion binding; terpenoid biosynthetic process; thiamine biosynthetic process; thiamine pyrophosphate binding,PF13292;PF02779;PF02780;,3.00E-143,CHOYP_KIF2A.2.2,,,,,,,DXS_HAEIG,Haemophilus influenzae (strain PittGG),1-deoxy-D-xylulose 5-phosphate biosynthetic process [GO:0052865]; terpenoid biosynthetic process [GO:0016114]; thiamine biosynthetic process [GO:0009228] comp144071_c0_seq2,3090,35.9223,0.42564595,166,680,,0,P49432,"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)","Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)",GO:0006086; GO:0006006; GO:0005759; GO:0005739; GO:0004739; GO:0045254; GO:0006099,acetyl-CoA biosynthetic process from pyruvate; glucose metabolic process; mitochondrial matrix; mitochondrion; pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase complex; tricarboxylic acid cycle,PF02779;PF02780;,3.00E-143,CHOYP_KIF2A.2.2,,,,,,,ODPB_RAT,Rattus norvegicus (Rat),acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] comp144071_c0_seq3,3103,36.0296,0.42158643,284,405,,0,P49432,"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)","Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)",GO:0006086; GO:0006006; GO:0005759; GO:0005739; GO:0004739; GO:0045254; GO:0006099,acetyl-CoA biosynthetic process from pyruvate; glucose metabolic process; mitochondrial matrix; mitochondrion; pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase complex; tricarboxylic acid cycle,PF02779;PF02780;,1.00E-140,CHOYP_ODPB.1.1,,,,,,,ODPB_RAT,Rattus norvegicus (Rat),acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] comp144074_c0_seq1,3355,40.924,0.66231638,231,1500,,1.00E-176,Q9WV70,Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor),Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor),GO:0006915; GO:0035067; GO:0000122; GO:0005730; GO:0005654; GO:0031493; GO:0005634; GO:0002039; GO:0006351,"apoptotic process; negative regulation of histone acetylation; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleoplasm; nucleosomal histone binding; nucleus; p53 binding; transcription, DNA-dependent",PF03715;,1.00E-90,CHOYP_LOC101076180.1.1,,,,,,,NOC2L_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; chromatin assembly [GO:0031497]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of histone acetylation [GO:0035067]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleolus to nucleoplasm transport [GO:0032066]; ribosomal large subunit biogenesis [GO:0042273]; transcription, DNA-templated [GO:0006351]" comp144074_c0_seq2,2456,42.3046,0.73052177,105,449,,2.00E-180,Q3SYU1,Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor),Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor),GO:0006915; GO:0034644; GO:0031497; GO:0003682; GO:0002903; GO:0035067; GO:2001243; GO:0000122; GO:0005730; GO:0032066; GO:0005654; GO:0003714; GO:0006351,"apoptotic process; cellular response to UV; chromatin assembly; chromatin binding; negative regulation of B cell apoptotic process; negative regulation of histone acetylation; negative regulation of intrinsic apoptotic signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleolus to nucleoplasm transport; nucleoplasm; transcription corepressor activity; transcription, DNA-dependent",PF03715;,1.00E-90,CHOYP_LOC101076180.1.1,,,,,,,NOC2L_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; chromatin assembly [GO:0031497]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of histone acetylation [GO:0035067]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleolus to nucleoplasm transport [GO:0032066]; ribosomal large subunit biogenesis [GO:0042273]; transcription, DNA-templated [GO:0006351]" comp144075_c0_seq1,3665,42.3465,0.45858545,131,158,,0,Q9CZU3,Superkiller viralicidic activity 2-like 2 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2),Superkiller viralicidic activity 2-like 2 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2) (TRAMP-like complex helicase),GO:0005524; GO:0008026; GO:0008380; GO:0071013; GO:0000178; GO:0006397; GO:0000460; GO:0003676; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA splicing; catalytic step 2 spliceosome; exosome (RNase complex); mRNA processing; maturation of 5.8S rRNA; nucleic acid binding; nucleolus,PF00270;PF08148;PF00271;PF13234;,0,CHOYP_SK2L2.1.1,6.00E-11,ruditapes_c28533,,,,,SK2L2_MOUSE,Mus musculus (Mouse),maturation of 5.8S rRNA [GO:0000460]; mRNA processing [GO:0006397]; RNA catabolic process [GO:0006401]; RNA splicing [GO:0008380] comp144075_c0_seq2,3693,42.4045,0.46016706,48,291,,8.00E-116,O59801,Putative ATP-dependent RNA helicase C550.03c (EC 3.6.4.-),Putative ATP-dependent RNA helicase C550.03c (EC 3.6.4.-),GO:0005524; GO:0008026; GO:0003723; GO:0003724; GO:0055087; GO:0005829; GO:0006402; GO:0005730; GO:2000765,ATP binding; ATP-dependent helicase activity; RNA binding; RNA helicase activity; Ski complex; cytosol; mRNA catabolic process; nucleolus; regulation of cytoplasmic translation,PF00270;PF08148;PF00271;PF13234;,,,,,,,,,SKI2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"mRNA catabolic process [GO:0006402]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]" comp144077_c0_seq2,1933,27.8324,0.68654615,236,984,,,,,,,,,,,1.00E-16,ruditapes_c9745,,,,,,, comp144078_c3_seq2,2054,34.0312,0.45844774,17,165,,2.00E-77,Q9Z255,Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A),Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A),GO:0005524; GO:0006281; GO:0033503; GO:0001741; GO:0033522; GO:0001701; GO:0060135; GO:0000790; GO:0008284; GO:0070979; GO:0070936; GO:0051865; GO:0009411; GO:0004842,ATP binding; DNA repair; HULC complex; XY body; histone H2A ubiquitination; in utero embryonic development; maternal process involved in female pregnancy; nuclear chromatin; positive regulation of cell proliferation; protein K11-linked ubiquitination; protein K48-linked ubiquitination; protein autoubiquitination; response to UV; ubiquitin-protein ligase activity,PF00179;,,,,,,,,,UBE2A_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone ubiquitination [GO:0016574]; in utero embryonic development [GO:0001701]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of cell proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to UV [GO:0009411] comp144078_c3_seq3,949,35.1949,0.58318051,83,99,,3.00E-87,P25153,Ubiquitin-conjugating enzyme E2-17 kDa (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 6) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0006281; GO:0051299; GO:0005737; GO:0007052; GO:0043518; GO:1902166; GO:0005634; GO:0032436; GO:0042787; GO:0004842,"ATP binding; DNA repair; centrosome separation; cytoplasm; mitotic spindle organization; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; nucleus; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity",PF00179;,1.00E-140,CHOYP_UBE2A.1.1,1.00E-164,ruditapes_c12514,,,,,UBCD6_DROME,Drosophila melanogaster (Fruit fly),"centrosome organization [GO:0051297]; centrosome separation [GO:0051299]; DNA repair [GO:0006281]; endocytic recycling [GO:0032456]; histone ubiquitination [GO:0016574]; mitophagy [GO:0000422]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]" comp144081_c1_seq1,2199,47.1578,0.29515241,14,2295,female>male,8.00E-92,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp144083_c0_seq3,2436,29.5567,0.36244732,7,73,,8.00E-17,Q8MSF5,Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-),Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-),GO:0004521; GO:0016021; GO:0009303,endoribonuclease activity; integral to membrane; rRNA transcription,,,,6.00E-53,ruditapes_c1850,,,,,RNK_DROME,Drosophila melanogaster (Fruit fly),cellular response to virus [GO:0098586]; rRNA transcription [GO:0009303] comp144083_c0_seq5,2437,29.5035,0.36399503,0,0,,2.00E-23,Q8K3C0,Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-),Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-),GO:0004521; GO:0016021; GO:0009303,endoribonuclease activity; integral to membrane; rRNA transcription,,,,,,,,,,RNK_MOUSE,Mus musculus (Mouse),rRNA transcription [GO:0009303] comp144084_c0_seq1,3918,34.7371,0.52747049,4738,10894,,2.00E-91,Q5U2Z3,Nucleosome assembly protein 1-like 4,Nucleosome assembly protein 1-like 4,GO:0006334; GO:0005634,nucleosome assembly; nucleus,PF00956;,5.00E-147,CHOYP_LOC100377601.2.2,,,,,,,NP1L4_RAT,Rattus norvegicus (Rat),nucleosome assembly [GO:0006334] comp144086_c0_seq1,3843,42.2066,0.41273423,620,483,,4.00E-28,Q16960,"Dynein intermediate chain 3, ciliary","Dynein intermediate chain 3, ciliary",GO:0035085; GO:0030286; GO:0005874; GO:0003774,cilium axoneme; dynein complex; microtubule; motor activity,,0,CHOYP_WDR63.1.1,,,,,,,DYI3_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina), comp144086_c0_seq2,3262,44.206,0.40635755,54,20,,0,Q8IWG1,WD repeat-containing protein 63 (Testis development protein NYD-SP29),WD repeat-containing protein 63 (Testis development protein NYD-SP29),,,,0,CHOYP_WDR63.1.1,,,,,,,WDR63_HUMAN,Homo sapiens (Human), comp144090_c0_seq1,2288,40.9528,0.45982751,157,616,,2.00E-20,Q8R3B7,Bromodomain-containing protein 8,Bromodomain-containing protein 8,GO:0035267; GO:0043968; GO:0043967; GO:0005739; GO:0040008; GO:0006355; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitochondrion; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00439;,3.00E-58,CHOYP_BRD8.1.1,,,,,,,BRD8_MOUSE,Mus musculus (Mouse),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144090_c0_seq3,615,47.9675,0.65468772,8,38,,9.00E-49,Q8R3B7,Bromodomain-containing protein 8,Bromodomain-containing protein 8,GO:0035267; GO:0043968; GO:0043967; GO:0005739; GO:0040008; GO:0006355; GO:0006351,"NuA4 histone acetyltransferase complex; histone H2A acetylation; histone H4 acetylation; mitochondrion; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00439;,,,,,,,,,BRD8_MOUSE,Mus musculus (Mouse),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144092_c0_seq1,7569,45.9242,0.51519166,0,0,,,,,,,,,1.00E-158,CHOYP_BRAFLDRAFT_120607.3.3,,,,,,,,, comp144092_c0_seq2,7557,45.9442,0.51553281,24,0,,1.00E-81,Q5S003,Sperm-associated antigen 17 (Projection protein PF6 homolog),Sperm-associated antigen 17 (Projection protein PF6 homolog),GO:0005737; GO:0005874; GO:0036126,cytoplasm; microtubule; sperm flagellum,,,,,,,,,,SPG17_MOUSE,Mus musculus (Mouse),axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351] comp144092_c0_seq3,7533,45.8781,0.51602481,0,0,,1.00E-81,Q5S003,Sperm-associated antigen 17 (Projection protein PF6 homolog),Sperm-associated antigen 17 (Projection protein PF6 homolog),GO:0005737; GO:0005874; GO:0036126,cytoplasm; microtubule; sperm flagellum,,1.00E-158,CHOYP_BRAFLDRAFT_120607.3.3,,,,,,,SPG17_MOUSE,Mus musculus (Mouse),axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351] comp144092_c0_seq4,7521,45.9114,0.51611593,32,0,,9.00E-81,Q6Q759,Sperm-associated antigen 17 (Projection protein PF6 homolog),Sperm-associated antigen 17 (Projection protein PF6 homolog),GO:0005737; GO:0005874; GO:0005634; GO:0036126,cytoplasm; microtubule; nucleus; sperm flagellum,,4.00E-158,CHOYP_BRAFLDRAFT_120607.2.3,,,,,,,SPG17_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; cilium movement [GO:0003341] comp144092_c0_seq5,7506,45.8966,0.51745755,0,0,,1.00E-81,Q5S003,Sperm-associated antigen 17 (Projection protein PF6 homolog),Sperm-associated antigen 17 (Projection protein PF6 homolog),GO:0005737; GO:0005874; GO:0036126,cytoplasm; microtubule; sperm flagellum,,1.00E-158,CHOYP_BRAFLDRAFT_120607.3.3,,,,,,,SPG17_MOUSE,Mus musculus (Mouse),axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351] comp144092_c0_seq6,7530,45.9761,0.51667125,0,0,,,,,,,,,4.00E-158,CHOYP_BRAFLDRAFT_120607.2.3,,,,,,,,, comp144092_c0_seq7,7542,45.9427,0.51661209,0,0,,1.00E-81,Q5S003,Sperm-associated antigen 17 (Projection protein PF6 homolog),Sperm-associated antigen 17 (Projection protein PF6 homolog),GO:0005737; GO:0005874; GO:0036126,cytoplasm; microtubule; sperm flagellum,,1.00E-158,CHOYP_BRAFLDRAFT_120607.3.3,,,,,,,SPG17_MOUSE,Mus musculus (Mouse),axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351] comp144092_c0_seq8,7494,45.9301,0.51751853,0,0,,9.00E-81,Q6Q759,Sperm-associated antigen 17 (Projection protein PF6 homolog),Sperm-associated antigen 17 (Projection protein PF6 homolog),GO:0005737; GO:0005874; GO:0005634; GO:0036126,cytoplasm; microtubule; nucleus; sperm flagellum,,1.00E-158,CHOYP_BRAFLDRAFT_120607.3.3,1.00E-85,ruditapes_c12164,,,,,SPG17_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; cilium movement [GO:0003341] comp144093_c1_seq1,6470,44.2968,0.535035,3,14,,0,Q06A37,Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7),Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7),GO:0005524; GO:0003677; GO:0030217; GO:0007512; GO:0007628; GO:0048844; GO:0008015; GO:0007417; GO:0003682; GO:0016568; GO:0050890; GO:0021545; GO:0035116; GO:0060324; GO:0030540; GO:0003007; GO:0004386; GO:0001701; GO:0043584; GO:0005634; GO:0060021; GO:0040018; GO:0006364; GO:0060123; GO:0006355; GO:0060041; GO:0048752; GO:0007605; GO:0001501; GO:0006351,"ATP binding; DNA binding; T cell differentiation; adult heart development; adult walking behavior; artery morphogenesis; blood circulation; central nervous system development; chromatin binding; chromatin modification; cognition; cranial nerve development; embryonic hindlimb morphogenesis; face development; female genitalia development; heart morphogenesis; helicase activity; in utero embryonic development; nose development; nucleus; palate development; positive regulation of multicellular organism growth; rRNA processing; regulation of growth hormone secretion; regulation of transcription, DNA-dependent; retina development in camera-type eye; semicircular canal morphogenesis; sensory perception of sound; skeletal system development; transcription, DNA-dependent",PF07533;PF00385;PF00271;PF00176;,,,,,,,,,CHD7_CHICK,Gallus gallus (Chicken),"adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; artery morphogenesis [GO:0048844]; blood circulation [GO:0008015]; chromatin modification [GO:0016568]; cognition [GO:0050890]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; heart morphogenesis [GO:0003007]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; palate development [GO:0060021]; positive regulation of multicellular organism growth [GO:0040018]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; retina development in camera-type eye [GO:0060041]; rRNA processing [GO:0006364]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; transcription, DNA-templated [GO:0006351]" comp144093_c1_seq2,6446,44.3065,0.53352745,3,19,,3.00E-150,O16102,Chromodomain-helicase-DNA-binding protein 3 (EC 3.6.4.12) (ATP-dependent helicase Chd3),Chromodomain-helicase-DNA-binding protein 3 (EC 3.6.4.12) (ATP-dependent helicase Chd3),GO:0005524; GO:0008026; GO:0003677; GO:0006333; GO:0004386; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"ATP binding; ATP-dependent helicase activity; DNA binding; chromatin assembly or disassembly; helicase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00385;PF06465;PF00271;PF00628;PF00176;,0,CHOYP_CHD7.2.2,,,,,,,CHD3_DROME,Drosophila melanogaster (Fruit fly),"chromatin assembly or disassembly [GO:0006333]; nucleosome mobilization [GO:0042766]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144093_c1_seq4,6174,44.1205,0.52852271,1,11,,0,Q06A37,Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7),Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7),GO:0005524; GO:0003677; GO:0030217; GO:0007512; GO:0007628; GO:0048844; GO:0008015; GO:0007417; GO:0003682; GO:0016568; GO:0050890; GO:0021545; GO:0035116; GO:0060324; GO:0030540; GO:0003007; GO:0004386; GO:0001701; GO:0043584; GO:0005634; GO:0060021; GO:0040018; GO:0006364; GO:0060123; GO:0006355; GO:0060041; GO:0048752; GO:0007605; GO:0001501; GO:0006351,"ATP binding; DNA binding; T cell differentiation; adult heart development; adult walking behavior; artery morphogenesis; blood circulation; central nervous system development; chromatin binding; chromatin modification; cognition; cranial nerve development; embryonic hindlimb morphogenesis; face development; female genitalia development; heart morphogenesis; helicase activity; in utero embryonic development; nose development; nucleus; palate development; positive regulation of multicellular organism growth; rRNA processing; regulation of growth hormone secretion; regulation of transcription, DNA-dependent; retina development in camera-type eye; semicircular canal morphogenesis; sensory perception of sound; skeletal system development; transcription, DNA-dependent",PF07533;PF00385;PF00271;PF00176;,,,,,,,,,CHD7_CHICK,Gallus gallus (Chicken),"adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; artery morphogenesis [GO:0048844]; blood circulation [GO:0008015]; chromatin modification [GO:0016568]; cognition [GO:0050890]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; heart morphogenesis [GO:0003007]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; palate development [GO:0060021]; positive regulation of multicellular organism growth [GO:0040018]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; retina development in camera-type eye [GO:0060041]; rRNA processing [GO:0006364]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; transcription, DNA-templated [GO:0006351]" comp144093_c1_seq7,4931,43.3178,0.54879666,0,11,,7.00E-126,Q08773,ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2),ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2),GO:0005524; GO:0043044; GO:0008623; GO:0015616; GO:0003682; GO:0006338; GO:0000183; GO:0006348; GO:0004386; GO:0060195; GO:0046020; GO:0016584; GO:0034401; GO:0003697; GO:0006369,ATP binding; ATP-dependent chromatin remodeling; CHRAC; DNA translocase activity; chromatin binding; chromatin remodeling; chromatin silencing at rDNA; chromatin silencing at telomere; helicase activity; negative regulation of antisense RNA transcription; negative regulation of transcription from RNA polymerase II promoter by pheromones; nucleosome positioning; regulation of transcription by chromatin organization; single-stranded DNA binding; termination of RNA polymerase II transcription,PF09110;PF00271;PF09111;PF00176;,0,CHOYP_CHD7.2.2,,,,,,,ISW2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; negative regulation of antisense RNA transcription [GO:0060195]; negative regulation of transcription from RNA polymerase II promoter by pheromones [GO:0046020]; nucleosome positioning [GO:0016584]; termination of RNA polymerase II transcription [GO:0006369] comp144093_c1_seq8,464,42.4569,0.52830239,0,0,,3.00E-66,A2AJK6,Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7),Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7),GO:0005524; GO:0003677; GO:0030217; GO:0007512; GO:0007628; GO:0048844; GO:0008015; GO:0043010; GO:0003682; GO:0016568; GO:0050890; GO:0035116; GO:0060429; GO:0060324; GO:0030540; GO:0003007; GO:0004386; GO:0001701; GO:0043584; GO:0005634; GO:0042048; GO:0021772; GO:0021553; GO:0060021; GO:0040018; GO:0006364; GO:0060123; GO:0050767; GO:0006355; GO:0060041; GO:0048752; GO:0007605; GO:0001501; GO:0006351,"ATP binding; DNA binding; T cell differentiation; adult heart development; adult walking behavior; artery morphogenesis; blood circulation; camera-type eye development; chromatin binding; chromatin modification; cognition; embryonic hindlimb morphogenesis; epithelium development; face development; female genitalia development; heart morphogenesis; helicase activity; in utero embryonic development; nose development; nucleus; olfactory behavior; olfactory bulb development; olfactory nerve development; palate development; positive regulation of multicellular organism growth; rRNA processing; regulation of growth hormone secretion; regulation of neurogenesis; regulation of transcription, DNA-dependent; retina development in camera-type eye; semicircular canal morphogenesis; sensory perception of sound; skeletal system development; transcription, DNA-dependent",PF07533;PF00385;PF00271;PF00176;,3.00E-31,CHOYP_CHD7.2.2,,,,,,,CHD7_MOUSE,Mus musculus (Mouse),"adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; aorta development [GO:0035904]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; camera-type eye development [GO:0043010]; cardiac septum morphogenesis [GO:0060411]; central nervous system development [GO:0007417]; chromatin remodeling [GO:0006338]; cognition [GO:0050890]; cranial nerve development [GO:0021545]; ear morphogenesis [GO:0042471]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; genitalia development [GO:0048806]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; innervation [GO:0060384]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; locomotory behavior [GO:0007626]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; palate development [GO:0060021]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; retina development in camera-type eye [GO:0060041]; right ventricular compact myocardium morphogenesis [GO:0003226]; rRNA processing [GO:0006364]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; tissue remodeling [GO:0048771]; transcription, DNA-templated [GO:0006351]; ventricular trabecula myocardium morphogenesis [GO:0003222]" comp144094_c0_seq1,3640,42.3077,0.49650653,1146,5441,,0,Q8BH74,Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107),Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107),GO:0000777; GO:0006406; GO:0031965; GO:0034399; GO:0051292; GO:0031080; GO:0005487; GO:0015031; GO:0017056,condensed chromosome kinetochore; mRNA export from nucleus; nuclear membrane; nuclear periphery; nuclear pore complex assembly; nuclear pore outer ring; nucleocytoplasmic transporter activity; protein transport; structural constituent of nuclear pore,PF04121;,3.00E-73,CHOYP_NU107.1.2,,,,,,,NU107_MOUSE,Mus musculus (Mouse),"mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]" comp144095_c0_seq2,1057,38.8836,0.92222843,44,48,,1.00E-14,Q13641,Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1),Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1),GO:0007155; GO:0005783; GO:0005887,cell adhesion; endoplasmic reticulum; integral to plasma membrane,PF13855;PF01463;PF01462;,,,,,,,,,TPBG_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; positive regulation of synapse assembly [GO:0051965] comp144095_c1_seq3,2254,40.9494,0.35313637,188,589,,2.00E-11,B4S9D0,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,3.00E-14,CHOYP_DNJB5.1.1,,,,,,,DNAJ_PROA2,Prosthecochloris aestuarii (strain DSM 271 / SK 413),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144097_c2_seq1,7831,44.4132,0.50704991,2184,6997,,0,Q92616,Translational activator GCN1 (HsGCN1) (GCN1-like protein 1),eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1),GO:0006417; GO:0005840; GO:0008135,"regulation of translation; ribosome; translation factor activity, nucleic acid binding",,0,CHOYP_GCN1L.1.1,,,,,,,GCN1L_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of translation [GO:0006417] comp144098_c0_seq1,3876,40.1961,1.08973646,1811,4,male>female,1.00E-06,Q8C0Q9,Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF),Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF),GO:0030742; GO:0017034; GO:0005634; GO:0051056; GO:0007264,GTP-dependent protein binding; Rap guanyl-nucleotide exchange factor activity; nucleus; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00610;PF00617;PF00618;,,,,,,,,,RPGF5_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp144099_c0_seq1,2396,47.1202,0.45132751,203,78,,3.00E-127,Q86TZ1,Tetratricopeptide repeat protein 6 (TPR repeat protein 6),Tetratricopeptide repeat protein 6 (TPR repeat protein 6),,,PF00515;PF13181;,0,CHOYP_LOC587791.3.3,,,,,,,TTC6_HUMAN,Homo sapiens (Human), comp144099_c0_seq3,4412,47.1668,0.50912538,96,0,,6.00E-09,Q9M8Y0,Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT),Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT),GO:0007275; GO:0006493; GO:0016757,"multicellular organismal development; protein O-linked glycosylation; transferase activity, transferring glycosyl groups",PF13844;PF00515;PF13414;PF13176;PF13181;,,,,,,,,,SEC_ARATH,Arabidopsis thaliana (Mouse-ear cress),multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493] comp144099_c0_seq4,572,49.3007,0.40382706,2,10,,1.00E-05,Q80W98,Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2),Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2),GO:0030544; GO:0051087; GO:0008022; GO:0006457,Hsp70 protein binding; chaperone binding; protein C-terminus binding; protein folding,PF16546;PF00515;PF13414;,,,,,,,,,SGTB_RAT,Rattus norvegicus (Rat),protein folding [GO:0006457] comp144099_c0_seq5,795,47.9245,0.35100926,2,0,,3.00E-15,Q86TZ1,Tetratricopeptide repeat protein 6 (TPR repeat protein 6),Tetratricopeptide repeat protein 6 (TPR repeat protein 6),,,PF00515;PF13181;,7.00E-112,CHOYP_LOC587791.3.3,,,,,,,TTC6_HUMAN,Homo sapiens (Human), comp144100_c1_seq6,2154,40.4828,0.3126092,468,26,,2.00E-26,Q6IR42,Zinc finger CW-type PWWP domain protein 1,Zinc finger CW-type PWWP domain protein 1,GO:0008270,zinc ion binding,PF00855;PF07496;,5.00E-30,CHOYP_LOC100879901.1.1,,,,,,,ZCPW1_MOUSE,Mus musculus (Mouse), comp144101_c1_seq1,3392,34.3455,0.41574176,89,2342,,2.00E-92,Q29RV1,Protein disulfide-isomerase A4 (EC 5.3.4.1),Protein disulfide-isomerase A4 (EC 5.3.4.1),GO:0045454; GO:0005788; GO:0006662; GO:0042470; GO:0003756; GO:0015035; GO:0006457,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; melanosome; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding,PF00085;,5.00E-134,CHOYP_PDIA3.1.1,,,,,,,PDIA4_BOVIN,Bos taurus (Bovine),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp144101_c1_seq2,3405,34.2731,0.42602898,272,3386,,1.00E-152,Q8JG64,Protein disulfide-isomerase A3 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Glucose-regulated thiol oxidoreductase 58 kDa protein),Protein disulfide-isomerase A3 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Glucose-regulated thiol oxidoreductase 58 kDa protein),GO:0045454; GO:0009986; GO:0005788; GO:0006662; GO:0043065; GO:0003756; GO:0015035; GO:0006457,cell redox homeostasis; cell surface; endoplasmic reticulum lumen; glycerol ether metabolic process; positive regulation of apoptotic process; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding,PF00085;,5.00E-134,CHOYP_PDIA3.1.1,1.00E-45,ruditapes2_c2336,,,,,PDIA3_CHICK,Gallus gallus (Chicken),cell redox homeostasis [GO:0045454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp144104_c0_seq1,2443,35.571,0.40416527,301,28,,1.00E-88,Q4R8G6,Meiosis-specific with OB domain-containing protein,Meiosis-specific with OB domain-containing protein (EC 3.1.-.-),GO:0005737; GO:0007140,cytoplasm; male meiosis,PF16900;,7.00E-48,CHOYP_NEMVEDRAFT_V1G210850.1.1,,,,,,,MEIOB_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),double-strand break repair via homologous recombination [GO:0000724]; female meiosis I [GO:0007144]; fertilization [GO:0009566]; male meiosis [GO:0007140]; resolution of meiotic recombination intermediates [GO:0000712]; synapsis [GO:0007129] comp144105_c1_seq1,1400,36.4286,0.32318853,1488,5314,,1.00E-18,Q24407,"ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)","ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)",GO:0015986; GO:0015078; GO:0046331; GO:0000276,"ATP synthesis coupled proton transport; hydrogen ion transmembrane transporter activity; lateral inhibition; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",PF05511;,,,2.00E-11,ruditapes_lrc32848,,,,,ATP5J_DROME,Drosophila melanogaster (Fruit fly),ATP synthesis coupled proton transport [GO:0015986]; lateral inhibition [GO:0046331]; proton transport [GO:0015992] comp144105_c1_seq6,1572,35.2417,0.34867603,510,2283,,2.00E-18,Q24407,"ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)","ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)",GO:0015986; GO:0015078; GO:0046331; GO:0000276,"ATP synthesis coupled proton transport; hydrogen ion transmembrane transporter activity; lateral inhibition; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",PF05511;,,,3.00E-11,ruditapes_lrc33338,,,,,ATP5J_DROME,Drosophila melanogaster (Fruit fly),ATP synthesis coupled proton transport [GO:0015986]; lateral inhibition [GO:0046331]; proton transport [GO:0015992] comp144106_c0_seq1,1684,41.3895,0.31604895,0,0,,2.00E-173,O60678,Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3),Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3),GO:0005737; GO:0005829; GO:0046872; GO:0031397; GO:0016274; GO:0035242; GO:0005840,cytoplasm; cytosol; metal ion binding; negative regulation of protein ubiquitination; protein-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; ribosome,,2.00E-73,CHOYP_ANM3.1.1,,,,,,,ANM3_HUMAN,Homo sapiens (Human),"negative regulation of protein ubiquitination [GO:0031397]; regulation of transcription, DNA-templated [GO:0006355]" comp144106_c0_seq3,2254,38.2875,0.31014475,0,0,,9.00E-171,O60678,Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3),Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3),GO:0005737; GO:0005829; GO:0046872; GO:0031397; GO:0016274; GO:0035242; GO:0005840,cytoplasm; cytosol; metal ion binding; negative regulation of protein ubiquitination; protein-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; ribosome,,,,,,,,,,ANM3_HUMAN,Homo sapiens (Human),"negative regulation of protein ubiquitination [GO:0031397]; regulation of transcription, DNA-templated [GO:0006355]" comp144107_c0_seq2,3357,42.7167,0.51834662,36,72,,4.00E-34,Q8K4R9,Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP),Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP),GO:0007267; GO:0005737; GO:0000087; GO:0005634; GO:0004721; GO:0031616,cell-cell signaling; cytoplasm; mitotic M phase; nucleus; phosphoprotein phosphatase activity; spindle pole centrosome,PF03359;,2.00E-32,CHOYP_DLGAP5.1.1,,,,,,,DLGP5_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; signaling [GO:0023052] comp144110_c0_seq12,851,36.8978,0.41520525,38,106,,2.00E-34,Q5EBL8,PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein),PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein),GO:0016323; GO:0005737; GO:0005829; GO:0005576,basolateral plasma membrane; cytoplasm; cytosol; extracellular region,PF00595;,2.00E-37,CHOYP_PDZ11.2.2,,,,,,,PDZ11_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; exocytosis [GO:0006887]; ion transmembrane transport [GO:0034220]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; pantothenate metabolic process [GO:0015939]; protein localization to basolateral plasma membrane [GO:1903361]; transmembrane transport [GO:0055085] comp144110_c0_seq2,1113,35.8491,0.42029311,14,122,,1.00E-33,Q5EBL8,PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein),PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein),GO:0016323; GO:0005737; GO:0005829; GO:0005576,basolateral plasma membrane; cytoplasm; cytosol; extracellular region,PF00595;,1.00E-34,CHOYP_PDZ11.2.2,,,,,,,PDZ11_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; exocytosis [GO:0006887]; ion transmembrane transport [GO:0034220]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; pantothenate metabolic process [GO:0015939]; protein localization to basolateral plasma membrane [GO:1903361]; transmembrane transport [GO:0055085] comp144111_c0_seq1,2918,42.0493,0.3962028,298,930,,3.00E-39,Q4QY64,ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein),ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein),GO:0005524; GO:0017111; GO:0005634; GO:0006974,ATP binding; nucleoside-triphosphatase activity; nucleus; response to DNA damage stimulus,PF00004;,,,,,,,,,ATAD5_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; immunoglobulin production [GO:0002377]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990] comp144112_c1_seq2,921,42.5624,0.60914448,0,0,,,,,,,,,2.00E-19,CHOYP_ZC3H4.1.1,,,,,,,,, comp144112_c1_seq4,2376,44.234,0.46897341,210,213,,8.00E-33,Q8BYK8,Zinc finger CCCH domain-containing protein 6,Zinc finger CCCH domain-containing protein 6,GO:0046872,metal ion binding,PF00642;,,,,,,,,,ZC3H6_MOUSE,Mus musculus (Mouse), comp144112_c1_seq6,800,40.375,0.63850239,4,0,,,,,,,,,,,4.00E-24,ruditapes_c9596,,,,,,, comp144112_c1_seq7,910,43.7363,0.61835344,10,0,,4.00E-06,Q1EHT7,Zinc finger CCCH domain-containing protein 4 (OsC3H4) (EC 3.6.4.-),Zinc finger CCCH domain-containing protein 4 (OsC3H4) (EC 3.6.4.-),GO:0005524; GO:0008026; GO:0003677; GO:0046872,ATP binding; ATP-dependent helicase activity; DNA binding; metal ion binding,PF00270;PF00271;PF00642;,2.00E-19,CHOYP_ZC3H4.1.1,,,,,,,C3H4_ORYSJ,Oryza sativa subsp. japonica (Rice),RNA processing [GO:0006396] comp144113_c0_seq1,2882,31.3324,0.38542785,1288,572,,6.00E-06,Q6PIF2,Synaptonemal complex central element protein 2 (Central element synaptonemal complex protein 1),Synaptonemal complex central element protein 2 (Central element synaptonemal complex protein 1),GO:0051301; GO:0000801; GO:0007130,cell division; central element; synaptonemal complex assembly,,,,,,,,,,SYCE2_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; synaptonemal complex assembly [GO:0007130] comp144115_c0_seq1,3725,38.2013,0.51143447,293,485,,0,P62205,Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1),Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1),GO:0005524; GO:0031572; GO:0051301; GO:0005813; GO:0005737; GO:0000776; GO:0030496; GO:0007067; GO:0005634; GO:0071168; GO:0004674; GO:0005819,ATP binding; G2 DNA damage checkpoint; cell division; centrosome; cytoplasm; kinetochore; midbody; mitosis; nucleus; protein localization to chromatin; protein serine/threonine kinase activity; spindle,PF00069;PF00659;,0,CHOYP_PLK1.1.2,,,,,,,PLK1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468] comp144115_c0_seq2,2555,37.7691,0.49645214,10,6,,1.00E-116,P62205,Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1),Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1),GO:0005524; GO:0031572; GO:0051301; GO:0005813; GO:0005737; GO:0000776; GO:0030496; GO:0007067; GO:0005634; GO:0071168; GO:0004674; GO:0005819,ATP binding; G2 DNA damage checkpoint; cell division; centrosome; cytoplasm; kinetochore; midbody; mitosis; nucleus; protein localization to chromatin; protein serine/threonine kinase activity; spindle,PF00069;PF00659;,1.00E-128,CHOYP_PLK1.1.2,,,,,,,PLK1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468] comp144116_c0_seq2,3563,42.2678,0.58952203,51,100,,1.00E-94,Q7ZY18,Zygotic DNA replication licensing factor mcm6-B (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b),Zygotic DNA replication licensing factor mcm6-B (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006270; GO:0042555; GO:0007049; GO:0046872; GO:0005634; GO:0030174,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication initiation; MCM complex; cell cycle; metal ion binding; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF14551;,,,,,,,,,MC6ZB_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp144116_c0_seq3,3475,42.4748,0.57778828,114,1529,,0,Q6DIH3,DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2),DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2),GO:0005524; GO:0006200; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0000785; GO:0046872; GO:0005634; GO:0030174,ATP binding; ATP catabolic process; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; chromatin; metal ion binding; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF12619;PF14551;,0,CHOYP_MCM2.1.1,,,,,,,MCM2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp144116_c0_seq4,3650,42.0548,0.5877355,99,309,,2.00E-102,Q9FL33,DNA replication licensing factor MCM3 homolog (EC 3.6.4.12) (Minichromosome maintenance protein 3 homolog),DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3) (AtMCM3),GO:0005524; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0005634,ATP binding; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; nucleus,PF00493;PF14551;,,,,,,,,,MCM3_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268] comp144116_c0_seq6,3539,42.3283,0.59085636,196,202,,0,Q6DIH3,DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2),DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2),GO:0005524; GO:0006200; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0000785; GO:0046872; GO:0005634; GO:0030174,ATP binding; ATP catabolic process; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; chromatin; metal ion binding; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF12619;PF14551;,0,CHOYP_MCM2.1.1,2.00E-157,ruditapes_c15762,3.00E-97,AM861509.p.cg.6,9,,MCM2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp144120_c0_seq3,815,46.7485,0.51776728,8,8,,2.00E-17,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144120_c0_seq5,1330,47.0677,0.5305068,4,22,,1.00E-16,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144123_c0_seq2,814,35.1351,0.48596347,176,962,,6.00E-07,Q9W4L1,"39S ribosomal protein L33, mitochondrial (L33mt) (MRP-L33)","39S ribosomal protein L33, mitochondrial (L33mt) (MRP-L33)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,,,,,,,,,,RM33_DROME,Drosophila melanogaster (Fruit fly),translation [GO:0006412] comp144123_c0_seq3,2231,30.883,0.64056736,667,52,,3.00E-34,Q9JJ94,Sjoegren syndrome nuclear autoantigen 1 homolog,Sjoegren syndrome nuclear autoantigen 1 homolog,GO:0005813; GO:0060830; GO:0005737; GO:0042073; GO:0005634,centrosome; ciliary receptor clustering involved in smoothened signaling pathway; cytoplasm; intraflagellar transport; nucleus,,1.00E-76,CHOYP_BRAFLDRAFT_57176.5.5,,,5.00E-77,EE677599.p.cg.6,5,,SSNA1_MOUSE,Mus musculus (Mouse),ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; intraciliary transport [GO:0042073] comp144124_c0_seq12,1638,48.2295,0.61987844,0,0,,1.00E-165,Q60520,Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a),Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a),GO:0003677; GO:0006260; GO:0001106; GO:0016580; GO:0002218; GO:0034613; GO:0071333; GO:0003682; GO:0001701; GO:0000776; GO:0043066; GO:1901675; GO:1900181; GO:2000678; GO:0005730; GO:0010971; GO:0031937; GO:0002230; GO:0045944; GO:0033558; GO:0051595; GO:0003700; GO:0005667; GO:0017053,DNA binding; DNA replication; RNA polymerase II transcription corepressor activity; Sin3 complex; activation of innate immune response; cellular protein localization; cellular response to glucose stimulus; chromatin binding; in utero embryonic development; kinetochore; negative regulation of apoptotic process; negative regulation of histone H3-K27 acetylation; negative regulation of protein localization to nucleus; negative regulation of transcription regulatory region DNA binding; nucleolus; positive regulation of G2/M transition of mitotic cell cycle; positive regulation of chromatin silencing; positive regulation of defense response to virus by host; positive regulation of transcription from RNA polymerase II promoter; protein deacetylase activity; response to methylglyoxal; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcriptional repressor complex,PF02671;PF08295;PF16879;,6.00E-148,CHOYP_BRAFLDRAFT_97881.1.1,,,,,,,SIN3A_MOUSE,Mus musculus (Mouse),"activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; chromatin silencing at rDNA [GO:0000183]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of hormone levels [GO:0010817]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144124_c0_seq2,3093,41.7071,0.72575316,8,28,,9.00E-110,O75182,Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b),Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b),GO:0000805; GO:0001741; GO:0000806; GO:0030849; GO:0048738; GO:0044255; GO:0003682; GO:0005737; GO:0045892; GO:0005654; GO:0007519; GO:0044281; GO:0003714; GO:0006351,"X chromosome; XY body; Y chromosome; autosome; cardiac muscle tissue development; cellular lipid metabolic process; chromatin binding; cytoplasm; negative regulation of transcription, DNA-dependent; nucleoplasm; skeletal muscle tissue development; small molecule metabolic process; transcription corepressor activity; transcription, DNA-dependent",PF02671;PF08295;PF16879;,,,,,,,,,SIN3B_HUMAN,Homo sapiens (Human),"cardiac muscle tissue development [GO:0048738]; cellular lipid metabolic process [GO:0044255]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp144124_c0_seq3,3073,41.7833,0.72071801,2,6,,2.00E-96,Q96ST3,Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a),Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a),GO:0003677; GO:0006260; GO:0001106; GO:0016580; GO:0002218; GO:0007568; GO:0007596; GO:0044255; GO:0034613; GO:0071333; GO:0003682; GO:0001701; GO:0000776; GO:0043066; GO:1901675; GO:1900181; GO:0000122; GO:2000678; GO:0005730; GO:0010971; GO:0031937; GO:0002230; GO:0045944; GO:0033558; GO:0043619; GO:0051595; GO:0010243; GO:0003700; GO:0044281; GO:0005667; GO:0017053,DNA binding; DNA replication; RNA polymerase II transcription corepressor activity; Sin3 complex; activation of innate immune response; aging; blood coagulation; cellular lipid metabolic process; cellular protein localization; cellular response to glucose stimulus; chromatin binding; in utero embryonic development; kinetochore; negative regulation of apoptotic process; negative regulation of histone H3-K27 acetylation; negative regulation of protein localization to nucleus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription regulatory region DNA binding; nucleolus; positive regulation of G2/M transition of mitotic cell cycle; positive regulation of chromatin silencing; positive regulation of defense response to virus by host; positive regulation of transcription from RNA polymerase II promoter; protein deacetylase activity; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; response to methylglyoxal; response to organonitrogen compound; sequence-specific DNA binding transcription factor activity; small molecule metabolic process; transcription factor complex; transcriptional repressor complex,PF02671;PF08295;PF16879;,1.00E-91,CHOYP_BRAFLDRAFT_97881.1.1,,,,,,,SIN3A_HUMAN,Homo sapiens (Human),"activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144124_c0_seq5,1242,49.3559,0.60892478,0,0,,7.00E-28,Q09750,Paired amphipathic helix protein pst1 (SIN3 homolog 1),Paired amphipathic helix protein pst1 (SIN3 homolog 1),GO:0033698; GO:0032221; GO:0007049; GO:0051301; GO:0005721; GO:0006338; GO:0030702; GO:0030261; GO:0016575; GO:0003714; GO:0006351,"Rpd3L complex; Rpd3S complex; cell cycle; cell division; centromeric heterochromatin; chromatin remodeling; chromatin silencing at centromere; chromosome condensation; histone deacetylation; transcription corepressor activity; transcription, DNA-dependent",PF02671;PF08295;PF16879;,,,,,,,,,PST1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin remodeling [GO:0006338]; chromatin silencing at centromere [GO:0030702]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp144124_c0_seq7,2912,41.5865,0.71480684,0,0,,3.00E-110,O75182,Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b),Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b),GO:0000805; GO:0001741; GO:0000806; GO:0030849; GO:0048738; GO:0044255; GO:0003682; GO:0005737; GO:0045892; GO:0005654; GO:0007519; GO:0044281; GO:0003714; GO:0006351,"X chromosome; XY body; Y chromosome; autosome; cardiac muscle tissue development; cellular lipid metabolic process; chromatin binding; cytoplasm; negative regulation of transcription, DNA-dependent; nucleoplasm; skeletal muscle tissue development; small molecule metabolic process; transcription corepressor activity; transcription, DNA-dependent",PF02671;PF08295;PF16879;,7.00E-30,CHOYP_PPAN-B.1.1,,,,,,,SIN3B_HUMAN,Homo sapiens (Human),"cardiac muscle tissue development [GO:0048738]; cellular lipid metabolic process [GO:0044255]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp144124_c0_seq8,2932,41.3711,0.7162394,0,0,,4.00E-97,Q96ST3,Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a),Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a),GO:0003677; GO:0006260; GO:0001106; GO:0016580; GO:0002218; GO:0007568; GO:0007596; GO:0044255; GO:0034613; GO:0071333; GO:0003682; GO:0001701; GO:0000776; GO:0043066; GO:1901675; GO:1900181; GO:0000122; GO:2000678; GO:0005730; GO:0010971; GO:0031937; GO:0002230; GO:0045944; GO:0033558; GO:0043619; GO:0051595; GO:0010243; GO:0003700; GO:0044281; GO:0005667; GO:0017053,DNA binding; DNA replication; RNA polymerase II transcription corepressor activity; Sin3 complex; activation of innate immune response; aging; blood coagulation; cellular lipid metabolic process; cellular protein localization; cellular response to glucose stimulus; chromatin binding; in utero embryonic development; kinetochore; negative regulation of apoptotic process; negative regulation of histone H3-K27 acetylation; negative regulation of protein localization to nucleus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription regulatory region DNA binding; nucleolus; positive regulation of G2/M transition of mitotic cell cycle; positive regulation of chromatin silencing; positive regulation of defense response to virus by host; positive regulation of transcription from RNA polymerase II promoter; protein deacetylase activity; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; response to methylglyoxal; response to organonitrogen compound; sequence-specific DNA binding transcription factor activity; small molecule metabolic process; transcription factor complex; transcriptional repressor complex,PF02671;PF08295;PF16879;,,,,,,,,,SIN3A_HUMAN,Homo sapiens (Human),"activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144124_c0_seq9,1662,48.3153,0.61905198,0,0,,9.00E-38,Q9LFQ3,Paired amphipathic helix protein Sin3-like 2,Paired amphipathic helix protein Sin3-like 2,GO:0005829; GO:0005634; GO:0006355; GO:0006351,"cytosol; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02671;PF08295;PF16879;,6.00E-136,CHOYP_BRAFLDRAFT_97881.1.1,,,,,,,SNL2_ARATH,Arabidopsis thaliana (Mouse-ear cress),"histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp144125_c0_seq2,3642,47.419,0.38106387,24,113,,,,,,,,,2.00E-18,CHOYP_BRAFLDRAFT_125701.1.3,,,,,,,,, comp144125_c0_seq3,4283,45.2253,0.40124799,54,152,,,,,,,,,3.00E-18,CHOYP_MATN1.3.5,2.00E-81,ruditapes2_c3122,,,,,,, comp144125_c0_seq4,1228,49.7557,0.38941724,0,0,,,,,,,,,8.00E-19,CHOYP_MATN1.3.5,,,,,,,,, comp144128_c0_seq10,768,43.8802,0.32681738,8,11,,6.00E-154,A8WIP6,Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20),Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20),GO:0005524; GO:0051301; GO:0005929; GO:0060271; GO:0004693; GO:0005737; GO:0007275; GO:0005634,ATP binding; cell division; cilium; cilium morphogenesis; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; multicellular organismal development; nucleus,PF00069;,3.00E-154,CHOYP_CDK20.1.1,,,,,,,CDK20_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle [GO:0007049]; cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275] comp144128_c0_seq5,924,42.8571,0.35756665,9,33,,9.00E-171,A8WIP6,Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20),Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20),GO:0005524; GO:0051301; GO:0005929; GO:0060271; GO:0004693; GO:0005737; GO:0007275; GO:0005634,ATP binding; cell division; cilium; cilium morphogenesis; cyclin-dependent protein serine/threonine kinase activity; cytoplasm; multicellular organismal development; nucleus,PF00069;,6.00E-171,CHOYP_CDK20.1.1,,,,,,,CDK20_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle [GO:0007049]; cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275] comp144129_c0_seq1,3839,32.8471,0.3807103,0,0,,3.00E-32,Q5R4T3,Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1),Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1),GO:0003677; GO:0007050; GO:0005737; GO:0002318; GO:0005634; GO:0006351,"DNA binding; cell cycle arrest; cytoplasm; myeloid progenitor cell differentiation; nucleus; transcription, DNA-dependent",PF10248;,,,,,,,,,MLF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell cycle arrest [GO:0007050]; myeloid progenitor cell differentiation [GO:0002318]; transcription, DNA-templated [GO:0006351]" comp144129_c0_seq4,3858,32.8409,0.37919126,0,0,,3.00E-32,Q5R4T3,Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1),Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1),GO:0003677; GO:0007050; GO:0005737; GO:0002318; GO:0005634; GO:0006351,"DNA binding; cell cycle arrest; cytoplasm; myeloid progenitor cell differentiation; nucleus; transcription, DNA-dependent",PF10248;,,,,,,,,,MLF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell cycle arrest [GO:0007050]; myeloid progenitor cell differentiation [GO:0002318]; transcription, DNA-templated [GO:0006351]" comp144129_c0_seq9,3888,32.8704,0.38520972,0,9,,3.00E-32,Q5R4T3,Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1),Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1),GO:0003677; GO:0007050; GO:0005737; GO:0002318; GO:0005634; GO:0006351,"DNA binding; cell cycle arrest; cytoplasm; myeloid progenitor cell differentiation; nucleus; transcription, DNA-dependent",PF10248;,,,,,,,,,MLF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"cell cycle arrest [GO:0007050]; myeloid progenitor cell differentiation [GO:0002318]; transcription, DNA-templated [GO:0006351]" comp144130_c0_seq1,1648,32.1602,0.50775679,298,1222,,4.00E-58,Q9D7M8,DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D),DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D),GO:0005665; GO:0003899; GO:0000166; GO:0006366,"DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; nucleotide binding; transcription from RNA polymerase II promoter",PF03874;,6.00E-85,CHOYP_LOC100711617.1.1,,,,,,,RPB4_MOUSE,Mus musculus (Mouse),"mRNA export from nucleus in response to heat stress [GO:0031990]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; piRNA metabolic process [GO:0034587]; positive regulation of translational initiation [GO:0045948]; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp144132_c0_seq1,4001,36.7908,0.54212853,588,899,,0,Q17GM7,"Probable citrate synthase 1, mitochondrial (EC 2.3.3.1)","Probable citrate synthase 1, mitochondrial (EC 2.3.3.16)",GO:0005975; GO:0044262; GO:0004108; GO:0005759; GO:0006099,carbohydrate metabolic process; cellular carbohydrate metabolic process; citrate (Si)-synthase activity; mitochondrial matrix; tricarboxylic acid cycle,PF00285;,0,CHOYP_CISY.1.1,3.00E-15,ruditapes_c4163,,,,,CISY1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),carbohydrate metabolic process [GO:0005975]; tricarboxylic acid cycle [GO:0006099] comp144132_c0_seq2,4028,36.6683,0.5420253,419,2346,,0,Q17GM7,"Probable citrate synthase 1, mitochondrial (EC 2.3.3.1)","Probable citrate synthase 1, mitochondrial (EC 2.3.3.16)",GO:0005975; GO:0044262; GO:0004108; GO:0005759; GO:0006099,carbohydrate metabolic process; cellular carbohydrate metabolic process; citrate (Si)-synthase activity; mitochondrial matrix; tricarboxylic acid cycle,PF00285;,0,CHOYP_CISY.1.1,2.00E-130,ruditapes_c2030,,,,,CISY1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),carbohydrate metabolic process [GO:0005975]; tricarboxylic acid cycle [GO:0006099] comp144133_c0_seq1,6599,44.2794,0.51023852,0,0,,7.00E-31,Q5XJV7,SET domain-containing protein 5,SET domain-containing protein 5,,,PF00856;,2.00E-23,CHOYP_LOC580083.1.1,,,,,,,SETD5_MOUSE,Mus musculus (Mouse), comp144133_c0_seq5,6146,44.6307,0.5001037,13,8,,7.00E-31,Q5XJV7,SET domain-containing protein 5,SET domain-containing protein 5,,,PF00856;,1.00E-23,CHOYP_LOC580083.1.1,,,,,,,SETD5_MOUSE,Mus musculus (Mouse), comp144133_c0_seq7,6521,44.2877,0.50989516,0,0,,7.00E-31,Q5XJV7,SET domain-containing protein 5,SET domain-containing protein 5,,,PF00856;,2.00E-23,CHOYP_LOC580083.1.1,,,,,,,SETD5_MOUSE,Mus musculus (Mouse), comp144134_c0_seq1,3980,46.5829,0.42674091,933,1003,,0,A6N6J5,WD repeat-containing protein 35 (Naofen),WD repeat-containing protein 35 (Naofen),GO:0005813; GO:0042384; GO:0035085; GO:0030991; GO:0005932,centrosome; cilium assembly; cilium axoneme; intraflagellar transport particle A; microtubule basal body,PF12894;,0,CHOYP_LOC100379049.1.1,,,,,,,WDR35_RAT,Rattus norvegicus (Rat),cilium assembly [GO:0042384]; intraciliary retrograde transport [GO:0035721]; protein localization to cilium [GO:0061512] comp144135_c1_seq2,1222,34.4517,0.6030576,703,964,,9.00E-13,Q8IXM3,"39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog)","39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog)",GO:0006915; GO:0007049; GO:0005762; GO:0003735; GO:0006412,apoptotic process; cell cycle; mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,PF09809;,,,,,,,,,RM41_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell cycle [GO:0007049]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412] comp144138_c0_seq1,2683,45.7324,0.54963551,482,732,,0,Q5ZIP4,5'-3' exoribonuclease 2 (EC 3.1.13.-),5'-3' exoribonuclease 2 (EC 3.1.13.-),GO:0008409; GO:0004534; GO:0000738; GO:0006353; GO:0016049; GO:0006397; GO:0003676; GO:0005730; GO:0006355; GO:0007283; GO:0008270,"5'-3' exonuclease activity; 5'-3' exoribonuclease activity; DNA catabolic process, exonucleolytic; DNA-dependent transcription, termination; cell growth; mRNA processing; nucleic acid binding; nucleolus; regulation of transcription, DNA-dependent; spermatogenesis; zinc ion binding",PF03159;,0,CHOYP_XRN2.1.1,,,,,,,XRN2_CHICK,Gallus gallus (Chicken),"cell growth [GO:0016049]; DNA catabolic process, exonucleolytic [GO:0000738]; DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]" comp144138_c0_seq3,488,40.7787,0.45166446,12,11,,4.00E-55,Q9H0D6,5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein),5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein),GO:0004534; GO:0000738; GO:0006353; GO:0006401; GO:0006396; GO:0016235; GO:0016049; GO:0006397; GO:0003676; GO:0005730; GO:0006355; GO:0007283; GO:0008270,"5'-3' exoribonuclease activity; DNA catabolic process, exonucleolytic; DNA-dependent transcription, termination; RNA catabolic process; RNA processing; aggresome; cell growth; mRNA processing; nucleic acid binding; nucleolus; regulation of transcription, DNA-dependent; spermatogenesis; zinc ion binding",PF03159;,5.00E-67,CHOYP_XRN2.1.1,,,,,,,XRN2_HUMAN,Homo sapiens (Human),"cell growth [GO:0016049]; DNA catabolic process, exonucleolytic [GO:0000738]; DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283]" comp144139_c0_seq1,4091,40.748,0.55105672,1126,218,,0,Q0V9R4,Coiled-coil domain-containing protein 39,Coiled-coil domain-containing protein 39,GO:0070286; GO:0060285; GO:0035085; GO:0005856; GO:0060287,axonemal dynein complex assembly; ciliary cell motility; cilium axoneme; cytoskeleton; epithelial cilium movement involved in determination of left/right asymmetry,,0,CHOYP_LOC100374491.1.1,,,,,,,CCD39_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; cilium movement [GO:0003341]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inner dynein arm assembly [GO:0036159] comp144139_c0_seq2,1294,44.8223,0.47791297,41,7,,2.00E-06,Q8JHV6,Laminin subunit beta-4,Laminin subunit beta-4,GO:0005604; GO:0007155,basement membrane; cell adhesion,PF00053;PF00055;,,,,,,,,,LAMB4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155] comp144140_c0_seq1,7208,42.8552,0.4054302,220,8,,2.00E-179,Q2IA00,Sperm flagellar protein 2 (Protein KPL2),Sperm flagellar protein 2 (Protein KPL2),GO:0005524; GO:0019205; GO:0006139,ATP binding; nucleobase-containing compound kinase activity; nucleobase-containing compound metabolic process,PF06294;,0,CHOYP_LOC100181095.1.1,8.00E-38,ruditapes_c15268,,,,,SPEF2_PIG,Sus scrofa (Pig), comp144140_c0_seq2,7256,42.9162,0.41681901,226,29,,3.00E-179,Q2IA00,Sperm flagellar protein 2 (Protein KPL2),Sperm flagellar protein 2 (Protein KPL2),GO:0005524; GO:0019205; GO:0006139,ATP binding; nucleobase-containing compound kinase activity; nucleobase-containing compound metabolic process,PF06294;,0,CHOYP_LOC100181095.1.1,,,,,,,SPEF2_PIG,Sus scrofa (Pig), comp144141_c1_seq2,531,31.6384,0.98364735,0,5,,,,,,,,,,,3.00E-11,ruditapes_lrc20076,,,,,,, comp144141_c1_seq4,554,31.769,0.94154032,10,35,,,,,,,,,,,2.00E-13,ruditapes_lrc23864,,,,,,, comp144142_c0_seq1,2925,38.1197,0.5231557,1441,2463,,4.00E-76,Q4R630,Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2),Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2),GO:0031262; GO:0051301; GO:0007059; GO:0000777; GO:0007067; GO:0007052; GO:0005634,Ndc80 complex; cell division; chromosome segregation; condensed chromosome kinetochore; mitosis; mitotic spindle organization; nucleus,PF03801;,,,,,,,,,NDC80_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052] comp144143_c1_seq1,3022,32.0318,0.40095073,252,1390,,1.00E-121,Q5RC74,Derlin-2 (Degradation in endoplasmic reticulum protein 2) (Der1-like protein 2),Derlin-2 (Degradation in endoplasmic reticulum protein 2) (Der1-like protein 2),GO:0030433; GO:0030968; GO:0030176; GO:0030307; GO:0008284; GO:0030970,"ER-associated protein catabolic process; endoplasmic reticulum unfolded protein response; integral to endoplasmic reticulum membrane; positive regulation of cell growth; positive regulation of cell proliferation; retrograde protein transport, ER to cytosol",,8.00E-112,CHOYP_LOC581513.1.1,,,,,,,DERL2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; retrograde protein transport, ER to cytosol [GO:0030970]; suckling behavior [GO:0001967]" comp144144_c0_seq1,3016,38.0968,0.63354127,34,295,,,,,,,,,9.00E-118,CHOYP_LOC100880308.1.1,,,,,,,,, comp144144_c0_seq2,3091,37.7871,0.62756634,49,326,,4.00E-77,Q9CQU1,Microfibrillar-associated protein 1,Microfibrillar-associated protein 1,GO:0005578,proteinaceous extracellular matrix,PF06991;,9.00E-118,CHOYP_LOC100880308.1.1,,,,,,,MFAP1_MOUSE,Mus musculus (Mouse), comp144146_c1_seq1,908,44.6035,0.47033517,52,39,,2.00E-74,P51112,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0005737; GO:0005634; GO:0048513; GO:0008134,cytoplasm; nucleus; organ development; transcription factor binding,PF12372;,6.00E-50,CHOYP_HTT.1.1,,,,,,,HD_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),animal organ development [GO:0048513] comp144147_c1_seq1,1683,34.284,0.6490812,29,121,,7.00E-24,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,2.00E-28,CHOYP_LOC100892567.8.8,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144147_c1_seq3,779,33.3761,0.74480906,47,163,,,,,,,,,3.00E-28,CHOYP_LOC764672.1.1,,,,,,,,, comp144151_c0_seq2,375,36,0.33676908,13,3,,2.00E-12,Q12001,"Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)","Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)",GO:0009060; GO:0042281; GO:0005783; GO:0005789; GO:0016021; GO:0006486,"aerobic respiration; dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein glycosylation",PF03155;,4.00E-41,CHOYP_ALG8.2.2,,,,,,,ALG6_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),aerobic respiration [GO:0009060]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487] comp144151_c0_seq3,2301,33.5941,0.47829768,258,1261,,,,,,,,,7.00E-23,CHOYP_ALG8.1.2,,,,,,,,, comp144151_c0_seq4,691,45.0072,0.40076199,11,53,,3.00E-87,Q9BVK2,"Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase)","Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase)",GO:0000033; GO:0006488; GO:0005789; GO:0016021; GO:0043687; GO:0018279,"alpha-1,3-mannosyltransferase activity; dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum membrane; integral to membrane; post-translational protein modification; protein N-linked glycosylation via asparagine",PF03155;,,,,,,,,,ALG8_HUMAN,Homo sapiens (Human),dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] comp144152_c0_seq1,3984,43.5743,0.96725371,17,106,,1.00E-74,P85521,Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],GO:0006953; GO:0005576; GO:0016021; GO:0005886; GO:0005044,acute-phase response; extracellular region; integral to membrane; plasma membrane; scavenger receptor activity,PF00530;,2.00E-38,CHOYP_LOC757057.1.5,,,,,,,C163A_BOVIN,Bos taurus (Bovine),acute-phase response [GO:0006953] comp144152_c0_seq2,3995,43.6295,0.96203569,57,162,,1.00E-85,Q9UGM3,Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein),Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein),GO:0048306; GO:0051607; GO:0030855; GO:0005576; GO:0019898; GO:0043152; GO:0045087; GO:0001833; GO:0019048; GO:0030670; GO:0030858; GO:0015031; GO:0005578; GO:0005044; GO:0008329; GO:0035375; GO:0042589,calcium-dependent protein binding; defense response to virus; epithelial cell differentiation; extracellular region; extrinsic to membrane; induction of bacterial agglutination; innate immune response; inner cell mass cell proliferation; modulation by virus of host morphology or physiology; phagocytic vesicle membrane; positive regulation of epithelial cell differentiation; protein transport; proteinaceous extracellular matrix; scavenger receptor activity; signaling pattern recognition receptor activity; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,2.00E-38,CHOYP_LOC757057.1.5,,,,,,,DMBT1_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]; viral process [GO:0016032] comp144152_c0_seq3,1088,46.6912,1.02966433,0,4,,5.00E-37,F7J220,Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),GO:0030659; GO:0045087; GO:0016021; GO:0006909; GO:0005044,cytoplasmic vesicle membrane; innate immune response; integral to membrane; phagocytosis; scavenger receptor activity,PF00530;PF00084;,,,,,,,,,SRCR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),innate immune response [GO:0045087]; phagocytosis [GO:0006909] comp144153_c0_seq1,4333,34.2257,0.44146785,70,145,,6.00E-38,P37942,Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase),Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase),GO:0043754; GO:0006096,dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; glycolysis,PF00198;PF00364;PF02817;,,,,,,,,,ODB2_BACSU,Bacillus subtilis (strain 168),glycolytic process [GO:0006096] comp144153_c0_seq2,4177,34.3309,0.40636966,51,131,,1.00E-146,Q90512,"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) (Fragment)","Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) (Fragment)",GO:0033512; GO:0004149; GO:0005739; GO:0045252; GO:0006099,L-lysine catabolic process to acetyl-CoA via saccharopine; dihydrolipoyllysine-residue succinyltransferase activity; mitochondrion; oxoglutarate dehydrogenase complex; tricarboxylic acid cycle,PF00198;PF00364;,3.00E-74,CHOYP_LOC100689951.1.1,,,,,,,ODO2_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099] comp144154_c0_seq1,3535,35.0778,0.52298855,0,0,,3.00E-95,Q24331,"Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)","Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)",GO:0005524; GO:0046872; GO:0005741; GO:0007275; GO:0006457; GO:0009408,ATP binding; metal ion binding; mitochondrial outer membrane; multicellular organismal development; protein folding; response to heat,PF00226;PF01556;PF00684;,,,,,,,,,TID_DROVI,Drosophila virilis (Fruit fly),multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq10,3616,34.9558,0.52373952,0,0,,3.00E-06,Q1I490,Curved DNA-binding protein,Curved DNA-binding protein,GO:0003681; GO:0005737; GO:0009295; GO:0006457,bent DNA binding; cytoplasm; nucleoid; protein folding,PF00226;PF01556;,,,,,,,,,CBPA_PSEE4,Pseudomonas entomophila (strain L48),protein folding [GO:0006457] comp144154_c0_seq11,1445,42.3529,0.51752046,0,0,,7.00E-41,Q8CP18,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,3.00E-31,CHOYP_LOC100909243.1.1,,,,,,,DNAJ_STAES,Staphylococcus epidermidis (strain ATCC 12228),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq12,3130,35.6869,0.52924279,0,8,,1.00E-97,Q24331,"Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)","Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)",GO:0005524; GO:0046872; GO:0005741; GO:0007275; GO:0006457; GO:0009408,ATP binding; metal ion binding; mitochondrial outer membrane; multicellular organismal development; protein folding; response to heat,PF00226;PF01556;PF00684;,2.00E-31,CHOYP_DNJA3.1.1,,,,,,,TID_DROVI,Drosophila virilis (Fruit fly),multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq2,1758,42.0364,0.54760078,0,0,,3.00E-55,A1KR91,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,4.00E-31,CHOYP_LOC100909243.1.1,,,,,,,DNAJ_NEIMF,Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq3,1281,43.5597,0.53198614,0,0,,9.00E-48,C5D4U0,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,7.00E-32,CHOYP_DNJA3.1.1,,,,,,,DNAJ_GEOSW,Geobacillus sp. (strain WCH70),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq4,3765,35.5113,0.55428003,2,0,,4.00E-114,Q27237,"Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID50) (TID56)","Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID50) (TID56)",GO:0005524; GO:0005829; GO:0046872; GO:0005741; GO:0005739; GO:0007275; GO:0006457; GO:0009408; GO:0007224,ATP binding; cytosol; metal ion binding; mitochondrial outer membrane; mitochondrion; multicellular organismal development; protein folding; response to heat; smoothened signaling pathway,PF00226;PF01556;PF00684;,,,,,,,,,TID_DROME,Drosophila melanogaster (Fruit fly),mitochondrion organization [GO:0007005]; multicellular organism development [GO:0007275]; protein folding [GO:0006457]; regulation of apoptotic process [GO:0042981]; response to heat [GO:0009408]; sleep [GO:0030431]; smoothened signaling pathway [GO:0007224] comp144154_c0_seq5,3687,35.6116,0.55403716,0,0,,4.00E-122,Q24331,"Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)","Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)",GO:0005524; GO:0046872; GO:0005741; GO:0007275; GO:0006457; GO:0009408,ATP binding; metal ion binding; mitochondrial outer membrane; multicellular organismal development; protein folding; response to heat,PF00226;PF01556;PF00684;,,,,,,,,,TID_DROVI,Drosophila virilis (Fruit fly),multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq6,3852,35.4881,0.54343915,0,0,,3.00E-52,Q5F5M1,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ_NEIG1,Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq7,1594,42.9737,0.56139261,0,0,,3.00E-129,Q24331,"Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)","Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)",GO:0005524; GO:0046872; GO:0005741; GO:0007275; GO:0006457; GO:0009408,ATP binding; metal ion binding; mitochondrial outer membrane; multicellular organismal development; protein folding; response to heat,PF00226;PF01556;PF00684;,9.00E-32,CHOYP_DNJA3.1.1,,,,,,,TID_DROVI,Drosophila virilis (Fruit fly),multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq8,3930,35.3944,0.54382306,0,0,,2.00E-39,Q8NLY8,Chaperone protein DnaJ 2,Chaperone protein DnaJ 2,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,8.00E-31,CHOYP_LOC100909243.1.1,,,,,,,DNAJ2_CORGL,Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144154_c0_seq9,2319,37.818,0.5314129,0,0,,4.00E-46,C5D4U0,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,1.00E-31,CHOYP_DNJA3.1.1,,,,,,,DNAJ_GEOSW,Geobacillus sp. (strain WCH70),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144155_c0_seq1,2094,45.0334,0.41223182,185,1378,,,,,,,,,2.00E-143,CHOYP_LOC100889564.1.1,,,,,,,,, comp144157_c2_seq11,1278,37.7934,0.28508985,0,0,,2.00E-17,Q80YD6,Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),GO:0005087; GO:0005737; GO:0045111; GO:0050709; GO:0005730; GO:0005634,Ran guanyl-nucleotide exchange factor activity; cytoplasm; intermediate filament cytoskeleton; negative regulation of protein secretion; nucleolus; nucleus,PF00415;,,,,,,,,,SRGEF_MOUSE,Mus musculus (Mouse),negative regulation of protein secretion [GO:0050709] comp144157_c2_seq19,1280,37.8906,0.28318556,0,0,,2.00E-17,Q80YD6,Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),GO:0005087; GO:0005737; GO:0045111; GO:0050709; GO:0005730; GO:0005634,Ran guanyl-nucleotide exchange factor activity; cytoplasm; intermediate filament cytoskeleton; negative regulation of protein secretion; nucleolus; nucleus,PF00415;,,,,,,,,,SRGEF_MOUSE,Mus musculus (Mouse),negative regulation of protein secretion [GO:0050709] comp144157_c2_seq25,1312,37.8811,0.29767474,0,0,,2.00E-17,Q80YD6,Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),GO:0005087; GO:0005737; GO:0045111; GO:0050709; GO:0005730; GO:0005634,Ran guanyl-nucleotide exchange factor activity; cytoplasm; intermediate filament cytoskeleton; negative regulation of protein secretion; nucleolus; nucleus,PF00415;,,,,,,,,,SRGEF_MOUSE,Mus musculus (Mouse),negative regulation of protein secretion [GO:0050709] comp144157_c2_seq32,1289,37.9364,0.28053816,0,0,,2.00E-17,Q80YD6,Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),GO:0005087; GO:0005737; GO:0045111; GO:0050709; GO:0005730; GO:0005634,Ran guanyl-nucleotide exchange factor activity; cytoplasm; intermediate filament cytoskeleton; negative regulation of protein secretion; nucleolus; nucleus,PF00415;,,,,,,,,,SRGEF_MOUSE,Mus musculus (Mouse),negative regulation of protein secretion [GO:0050709] comp144157_c2_seq49,1268,38.0126,0.28403454,0,0,,2.00E-17,Q80YD6,Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),GO:0005087; GO:0005737; GO:0045111; GO:0050709; GO:0005730; GO:0005634,Ran guanyl-nucleotide exchange factor activity; cytoplasm; intermediate filament cytoskeleton; negative regulation of protein secretion; nucleolus; nucleus,PF00415;,,,,,,,,,SRGEF_MOUSE,Mus musculus (Mouse),negative regulation of protein secretion [GO:0050709] comp144159_c0_seq1,3166,35.439,0.50489113,0,0,,6.00E-23,Q12546,Acid phosphatase (EC 3.1.3.2) (APase6) (pH 6-optimum acid phosphatase),Acid phosphatase (EC 3.1.3.2) (APase6) (pH 6-optimum acid phosphatase),GO:0003993; GO:0005576; GO:0046872,acid phosphatase activity; extracellular region; metal ion binding,PF00149;PF14008;PF16656;,9.00E-80,CHOYP_LOC100366862.1.1,1.00E-101,ruditapes_c8668,,,,,PPA_ASPFI,Aspergillus ficuum, comp144159_c0_seq3,3347,34.9567,0.5295855,1,3,,7.00E-21,Q6TPH1,Purple acid phosphatase 23 (EC 3.1.3.2),Purple acid phosphatase 23 (EC 3.1.3.2),GO:0003993; GO:0005576; GO:0046872,acid phosphatase activity; extracellular region; metal ion binding,PF00149;PF16656;,,,,,,,,,PPA23_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp144159_c0_seq4,3442,34.5729,0.53674891,24,221,,9.00E-147,Q8BX37,Iron/zinc purple acid phosphatase-like protein (EC 3.1.3.2),Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form),GO:0003993; GO:0005576; GO:0046872,acid phosphatase activity; extracellular region; metal ion binding,PF00149;PF14008;PF16656;,,,,,,,,,PAPL_MOUSE,Mus musculus (Mouse), comp144159_c0_seq6,3261,34.9893,0.49290124,2,21,,2.00E-147,Q8BX37,Iron/zinc purple acid phosphatase-like protein (EC 3.1.3.2),Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form),GO:0003993; GO:0005576; GO:0046872,acid phosphatase activity; extracellular region; metal ion binding,PF00149;PF14008;PF16656;,9.00E-80,CHOYP_LOC100366862.1.1,3.00E-65,ruditapes_c14324,,,,,PAPL_MOUSE,Mus musculus (Mouse), comp144162_c0_seq2,3633,38.0952,0.50465429,2370,498,,1.00E-69,Q95JL5,WD repeat-containing protein 16,Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16),GO:0005737,cytoplasm,PF00400;,2.00E-37,CHOYP_BRAFLDRAFT_125119.1.1,8.00E-35,ruditapes_c8971,,,,,WDR16_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp144164_c0_seq1,7134,41.7718,0.45349385,31,24,,1.00E-92,Q587J7,Tudor domain-containing protein 12 (ES cell-associated transcript 8 protein),Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF00567;,,,,,,,,,TDR12_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283] comp144164_c0_seq2,7238,41.6275,0.45308581,25,6,,1.00E-92,Q587J7,Tudor domain-containing protein 12 (ES cell-associated transcript 8 protein),Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF00567;,,,,,,,,,TDR12_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283] comp144164_c0_seq4,1638,41.5751,0.53816662,0,3,,7.00E-34,Q8W4R3,DEAD-box ATP-dependent RNA helicase 30 (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase 30 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0000184; GO:0005634; GO:0006364,"ATP binding; ATP-dependent helicase activity; RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; rRNA processing",PF00270;PF00271;,,,,,,,,,RH30_ARATH,Arabidopsis thaliana (Mouse-ear cress),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]" comp144164_c0_seq5,3387,43.3127,0.51613126,3,0,,5.00E-41,Q9CWU0,Tudor domain-containing protein 12 (ES cell-associated transcript 8 protein),Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF04969;PF00270;PF00567;,,,,,,,,,TDR12_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283] comp144164_c0_seq6,3117,42.9901,0.53887009,2,0,,4.00E-95,Q587J7,Tudor domain-containing protein 12 (ES cell-associated transcript 8 protein),Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF00567;,,,,,,,,,TDR12_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283] comp144165_c1_seq1,3308,38.9661,0.42889953,2979,11285,,5.00E-90,Q9BXM7,"Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)","Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)",GO:0005524; GO:0010857; GO:0008219; GO:0097237; GO:0005829; GO:0016021; GO:0007243; GO:0000287; GO:0005741; GO:0005739; GO:0000422; GO:0043524; GO:0018105; GO:0043123; GO:0033603; GO:0090200; GO:0032226; GO:0004674; GO:0043254; GO:0031396; GO:0006950,"ATP binding; calcium-dependent protein kinase activity; cell death; cellular response to toxic substance; cytosol; integral to membrane; intracellular protein kinase cascade; magnesium ion binding; mitochondrial outer membrane; mitochondrion; mitochondrion degradation; negative regulation of neuron apoptotic process; peptidyl-serine phosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of dopamine secretion; positive regulation of release of cytochrome c from mitochondria; positive regulation of synaptic transmission, dopaminergic; protein serine/threonine kinase activity; regulation of protein complex assembly; regulation of protein ubiquitination; response to stress",PF00069;,,,3.00E-52,ruditapes_c7870,,,,,PINK1_HUMAN,Homo sapiens (Human),"activation of protein kinase B activity [GO:0032148]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; establishment of protein localization to mitochondrion [GO:0072655]; intracellular signal transduction [GO:0035556]; macroautophagy [GO:0016236]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1903147]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cristae formation [GO:1903852]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of free ubiquitin chain polymerization [GO:1904544]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of peptidase activity [GO:0010952]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of mitophagy [GO:1903146]; regulation of oxidative phosphorylation [GO:0002082]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein complex assembly [GO:0043254]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of synaptic vesicle transport [GO:1902803]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; response to stress [GO:0006950]; TORC2 signaling [GO:0038203]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp144166_c0_seq1,2195,43.3257,0.55943305,53,189,,1.00E-175,Q503E1,Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein),Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein),GO:0016787; GO:0005634,hydrolase activity; nucleus,PF10996;PF16661;PF07521;,,,,,,,,,INT11_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of RNA splicing [GO:0043484] comp144166_c0_seq4,1972,43.6105,0.59150438,22,43,,0,Q503E1,Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein),Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein),GO:0016787; GO:0005634,hydrolase activity; nucleus,PF10996;PF16661;PF07521;,0,CHOYP_INT11.1.1,,,,,,,INT11_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of RNA splicing [GO:0043484] comp144166_c0_seq6,1074,41.3408,0.65662278,9,0,,,,,,,,,0,CHOYP_INT11.1.1,,,,,,,,, comp144168_c0_seq1,3836,41.0323,0.41564178,784,813,,1.00E-154,Q9VRP9,E3 ubiquitin-protein ligase Bre1 (EC 6.3.2.-) (dBre1),E3 ubiquitin-protein ligase Bre1 (EC 6.3.2.-) (dBre1),GO:0007219; GO:0016574; GO:0016874; GO:0005634; GO:0006909; GO:0006513; GO:0008270,Notch signaling pathway; histone ubiquitination; ligase activity; nucleus; phagocytosis; protein monoubiquitination; zinc ion binding,PF00097;,0,CHOYP_LOC660381.1.1,9.00E-79,ruditapes_c18344,,,,,BRE1_DROME,Drosophila melanogaster (Fruit fly),histone modification [GO:0016570]; histone ubiquitination [GO:0016574]; Notch signaling pathway [GO:0007219]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; protein monoubiquitination [GO:0006513]; sleep [GO:0030431] comp144168_c1_seq1,1558,41.4634,0.6008422,7,15,,5.00E-158,B1H2N3,"Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)","Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)",GO:0005509; GO:0070509; GO:0032592; GO:0051560; GO:0006851; GO:0005743,calcium ion binding; calcium ion import; integral to mitochondrial membrane; mitochondrial calcium ion homeostasis; mitochondrial calcium ion transport; mitochondrial inner membrane,PF13202;PF13833;,1.00E-113,CHOYP_LOC552081.1.1,,,,,,,MICU1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] comp144168_c1_seq3,1546,41.5265,0.60390396,2,0,,4.00E-115,A8WQT4,"Calcium uptake protein 1 homolog, mitochondrial","Calcium uptake protein 1 homolog, mitochondrial",GO:0005509; GO:0016021; GO:0031966,calcium ion binding; integral to membrane; mitochondrial membrane,PF13202;PF13833;,5.00E-111,CHOYP_LOC552081.1.1,,,,,,,MICU1_CAEBR,Caenorhabditis briggsae,calcium ion transport [GO:0006816]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] comp144169_c0_seq5,2250,39.1111,0.96536581,17,0,,8.00E-19,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp144169_c0_seq6,2318,38.654,0.97095565,98,138,,9.00E-19,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp144170_c0_seq1,4084,40.9892,1.02392983,0,848,female,,,,,,,,2.00E-63,CHOYP_LOC100373045.1.1,,,,,,,,, comp144170_c0_seq2,4056,41.0256,1.02378182,6,1047,female>male,,,,,,,,2.00E-63,CHOYP_LOC100373045.1.1,,,,,,,,, comp144171_c0_seq1,490,41.0204,0.68100145,8,1775,female>male,1.00E-12,Q9Y5Z4,Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL),Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL),GO:0005737; GO:0005739,cytoplasm; mitochondrion,PF04832;,,,,,,,,,HEBP2_HUMAN,Homo sapiens (Human),negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] comp144171_c1_seq1,2243,32.1444,0.57165366,170,28132,female>male,2.00E-10,Q6NU05,Heme-binding protein 1,Heme-binding protein 1,GO:0005737; GO:0020037,cytoplasm; heme binding,PF04832;,,,,,,,,,HEBP1_XENLA,Xenopus laevis (African clawed frog), comp144174_c1_seq11,1364,46.8475,0.60622393,0,0,,5.00E-71,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,2.00E-159,CHOYP_DNAH6.3.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144174_c1_seq6,1483,47.4713,0.59146135,257,0,male,4.00E-123,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH6.2.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144175_c1_seq7,1794,41.0256,0.40295562,126,498,,1.00E-91,Q9BWU0,Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein),Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00035;PF00498;,5.00E-86,CHOYP_LOC101169402.1.1,,,,,,,NADAP_HUMAN,Homo sapiens (Human), comp144177_c0_seq1,1674,40.7407,0.41048187,228,763,,2.00E-116,Q5RDP4,"Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)","Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)",GO:0005524; GO:0002161; GO:0004823; GO:0006429; GO:0005759; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; leucine-tRNA ligase activity; leucyl-tRNA aminoacylation; mitochondrial matrix; regulation of translational fidelity,PF08264;PF00133;,2.00E-46,CHOYP_LARS2.1.1,,,,,,,SYLM_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),leucyl-tRNA aminoacylation [GO:0006429] comp144178_c0_seq1,3905,35.1088,0.63306595,3,29,,1.00E-44,Q9YHU0,C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (C-terminal-binding protein A),C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (C-terminal-binding protein A),GO:0051287; GO:0045892; GO:0005634; GO:0016616,"NAD binding; negative regulation of transcription, DNA-dependent; nucleus; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF00389;PF02826;,3.00E-61,CHOYP_PHUM_PHUM549040.1.1,,,,,,,CTBP1_XENLA,Xenopus laevis (African clawed frog),"negative regulation of transcription, DNA-templated [GO:0045892]" comp144178_c0_seq4,5382,37.2352,0.72540293,0,0,,0,O46036,C-terminal-binding protein (CtBP protein) (dCtBP),C-terminal-binding protein (CtBP protein) (dCtBP),GO:0051287; GO:0016055; GO:0022416; GO:0001700; GO:0000122; GO:0005634; GO:0016616; GO:0046427; GO:0042803; GO:0030111; GO:0016360; GO:0003713; GO:0003714; GO:0006351; GO:0035220,"NAD binding; Wnt receptor signaling pathway; chaeta development; embryonic development via the syncytial blastoderm; negative regulation of transcription from RNA polymerase II promoter; nucleus; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; positive regulation of JAK-STAT cascade; protein homodimerization activity; regulation of Wnt receptor signaling pathway; sensory organ precursor cell fate determination; transcription coactivator activity; transcription corepressor activity; transcription, DNA-dependent; wing disc development",PF00389;PF02826;,0,CHOYP_PHUM_PHUM549040.1.1,,,,,,,CTBP_DROME,Drosophila melanogaster (Fruit fly),"ATP-dependent chromatin remodeling [GO:0043044]; chaeta development [GO:0022416]; embryonic development via the syncytial blastoderm [GO:0001700]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of JAK-STAT cascade [GO:0046427]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]; Wnt signaling pathway [GO:0016055]" comp144178_c0_seq5,5397,37.2429,0.72321622,1,0,,0,O46036,C-terminal-binding protein (CtBP protein) (dCtBP),C-terminal-binding protein (CtBP protein) (dCtBP),GO:0051287; GO:0016055; GO:0022416; GO:0001700; GO:0000122; GO:0005634; GO:0016616; GO:0046427; GO:0042803; GO:0030111; GO:0016360; GO:0003713; GO:0003714; GO:0006351; GO:0035220,"NAD binding; Wnt receptor signaling pathway; chaeta development; embryonic development via the syncytial blastoderm; negative regulation of transcription from RNA polymerase II promoter; nucleus; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; positive regulation of JAK-STAT cascade; protein homodimerization activity; regulation of Wnt receptor signaling pathway; sensory organ precursor cell fate determination; transcription coactivator activity; transcription corepressor activity; transcription, DNA-dependent; wing disc development",PF00389;PF02826;,0,CHOYP_PHUM_PHUM549040.1.1,,,,,,,CTBP_DROME,Drosophila melanogaster (Fruit fly),"ATP-dependent chromatin remodeling [GO:0043044]; chaeta development [GO:0022416]; embryonic development via the syncytial blastoderm [GO:0001700]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of JAK-STAT cascade [GO:0046427]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]; Wnt signaling pathway [GO:0016055]" comp144180_c0_seq1,2545,42.7505,0.4451187,32,139,,0,P54351,Vesicle-fusing ATPase 2 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 2) (NEM-sensitive fusion protein 2) (Vesicular-fusion protein NSF2) (dNsf-2) (NSF-2),Vesicle-fusing ATPase 2 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 2) (NEM-sensitive fusion protein 2) (Vesicular-fusion protein NSF2) (dNsf-2) (NSF-2),GO:0005524; GO:0005737; GO:0046872; GO:0007274; GO:0017111; GO:0015031; GO:0008582; GO:0016082,ATP binding; cytoplasm; metal ion binding; neuromuscular synaptic transmission; nucleoside-triphosphatase activity; protein transport; regulation of synaptic growth at neuromuscular junction; synaptic vesicle priming,PF00004;PF02933;PF02359;,0,CHOYP_BRAFLDRAFT_118310.1.1,,,,,,,NSF2_DROME,Drosophila melanogaster (Fruit fly),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; SNARE complex disassembly [GO:0035494]; synaptic vesicle priming [GO:0016082]; terminal branching, open tracheal system [GO:0007430]; trachea morphogenesis [GO:0060439]; vesicle-mediated transport [GO:0016192]" comp144180_c0_seq2,2859,42.5324,0.44762601,34,208,,0,P34732,Vesicular-fusion protein SEC18,Vesicular-fusion protein SEC18,GO:0005524; GO:0005737; GO:0017111; GO:0015031; GO:0016192,ATP binding; cytoplasm; nucleoside-triphosphatase activity; protein transport; vesicle-mediated transport,PF00004;PF02359;,,,,,,,,,SEC18_CANAX,Candida albicans (Yeast),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp144180_c0_seq3,2845,42.5659,0.44085224,68,249,,0,P54351,Vesicle-fusing ATPase 2 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 2) (NEM-sensitive fusion protein 2) (Vesicular-fusion protein NSF2) (dNsf-2) (NSF-2),Vesicle-fusing ATPase 2 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 2) (NEM-sensitive fusion protein 2) (Vesicular-fusion protein NSF2) (dNsf-2) (NSF-2),GO:0005524; GO:0005737; GO:0046872; GO:0007274; GO:0017111; GO:0015031; GO:0008582; GO:0016082,ATP binding; cytoplasm; metal ion binding; neuromuscular synaptic transmission; nucleoside-triphosphatase activity; protein transport; regulation of synaptic growth at neuromuscular junction; synaptic vesicle priming,PF00004;PF02933;PF02359;,,,,,,,,,NSF2_DROME,Drosophila melanogaster (Fruit fly),"ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; SNARE complex disassembly [GO:0035494]; synaptic vesicle priming [GO:0016082]; terminal branching, open tracheal system [GO:0007430]; trachea morphogenesis [GO:0060439]; vesicle-mediated transport [GO:0016192]" comp144182_c0_seq1,4504,38.6323,0.52169315,23,89,,0,P41541,General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein),General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein),GO:0000139; GO:0005829; GO:0006886; GO:0048471; GO:0008565; GO:0048280,Golgi membrane; cytosol; intracellular protein transport; perinuclear region of cytoplasm; protein transporter activity; vesicle fusion with Golgi apparatus,PF04871;PF04869;,,,,,,,,,USO1_BOVIN,Bos taurus (Bovine),ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; protein homooligomerization [GO:0051260]; transcytosis [GO:0045056]; vesicle fusion with Golgi apparatus [GO:0048280] comp144182_c0_seq2,4531,38.5566,0.50837618,51,143,,0,P41541,General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein),General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein),GO:0000139; GO:0005829; GO:0006886; GO:0048471; GO:0008565; GO:0048280,Golgi membrane; cytosol; intracellular protein transport; perinuclear region of cytoplasm; protein transporter activity; vesicle fusion with Golgi apparatus,PF04871;PF04869;,0,CHOYP_USO1.1.11,,,,,,,USO1_BOVIN,Bos taurus (Bovine),ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; protein homooligomerization [GO:0051260]; transcytosis [GO:0045056]; vesicle fusion with Golgi apparatus [GO:0048280] comp144183_c0_seq1,1785,41.3445,0.81372747,73,668,,,,,,,,,4.00E-30,CHOYP_BRAFLDRAFT_91636.1.11,3.00E-17,ruditapes_c9604,,,,,,, comp144183_c0_seq3,1408,41.5483,0.80698781,55,535,,2.00E-51,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,,,,,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp144186_c0_seq1,1855,44.0431,0.87615015,71,0,,5.00E-15,Q28GD5,Transcription factor Sox-7,Transcription factor Sox-7,GO:0001706; GO:0007507; GO:0005634; GO:0045944; GO:0048793; GO:0043565; GO:0044212; GO:0006351,"endoderm formation; heart development; nucleus; positive regulation of transcription from RNA polymerase II promoter; pronephros development; sequence-specific DNA binding; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00505;PF12067;,,,,,,,,,SOX7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"artery development [GO:0060840]; endoderm formation [GO:0001706]; heart development [GO:0007507]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephros development [GO:0048793]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]" comp144186_c0_seq2,4405,41.975,0.94091175,1736,1,male>female,1.00E-13,Q9BT81,Transcription factor SOX-7,Transcription factor SOX-7,GO:0003705; GO:0005737; GO:0001706; GO:0008285; GO:0045892; GO:0005634; GO:0043280; GO:0045893; GO:0060828; GO:0043565; GO:0003700; GO:0044212,"RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; cytoplasm; endoderm formation; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of transcription, DNA-dependent; regulation of canonical Wnt receptor signaling pathway; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding",PF00505;PF12067;,,,,,,,,,SOX7_HUMAN,Homo sapiens (Human),"endoderm formation [GO:0001706]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; regulation of canonical Wnt signaling pathway [GO:0060828]; transcription, DNA-templated [GO:0006351]" comp144186_c0_seq3,875,49.1429,0.87446133,12,0,,1.00E-16,O94993,Transcription factor SOX-30,Transcription factor SOX-30,GO:0005634; GO:0006355; GO:0031960; GO:0043565; GO:0000981; GO:0007283; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; response to corticosteroid stimulus; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; spermatogenesis; transcription, DNA-dependent",PF00505;,,,,,,,,,SOX30_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to corticosteroid [GO:0031960]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144189_c0_seq1,2679,42.5159,0.60087038,504,972,,7.00E-74,Q9UIG0,Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2),Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2),GO:0005524; GO:0043044; GO:0034725; GO:0071778; GO:0005721; GO:0003682; GO:0048096; GO:0000793; GO:0006302; GO:0003007; GO:0070577; GO:0035173; GO:0004715; GO:0032947; GO:0004713; GO:0006351; GO:0071884; GO:0008270,"ATP binding; ATP-dependent chromatin remodeling; DNA replication-dependent nucleosome disassembly; WINAC complex; centromeric heterochromatin; chromatin binding; chromatin-mediated maintenance of transcription; condensed chromosome; double-strand break repair; heart morphogenesis; histone acetyl-lysine binding; histone kinase activity; non-membrane spanning protein tyrosine kinase activity; protein complex scaffold; protein tyrosine kinase activity; transcription, DNA-dependent; vitamin D receptor activator activity; zinc ion binding",PF00439;PF00628;PF10537;PF15612;PF15613;,,,,,,,,,BAZ1B_HUMAN,Homo sapiens (Human),"cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; chromatin-mediated maintenance of transcription [GO:0048096]; double-strand break repair [GO:0006302]; heart morphogenesis [GO:0003007]; histone phosphorylation [GO:0016572]; positive regulation of gene expression, epigenetic [GO:0045815]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144189_c0_seq4,2797,40.0429,0.59962018,202,468,,4.00E-71,Q9Z277,Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor homolog) (Williams-Beuren syndrome chromosomal region 9 protein homolog),Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor homolog) (Williams-Beuren syndrome chromosomal region 9 protein homolog),GO:0005524; GO:0043044; GO:0034725; GO:0071778; GO:0005721; GO:0006333; GO:0003682; GO:0048096; GO:0000793; GO:0006302; GO:0003007; GO:0070577; GO:0035173; GO:0004715; GO:0043596; GO:0005634; GO:0004713; GO:0006351; GO:0071884; GO:0008270,"ATP binding; ATP-dependent chromatin remodeling; DNA replication-dependent nucleosome disassembly; WINAC complex; centromeric heterochromatin; chromatin assembly or disassembly; chromatin binding; chromatin-mediated maintenance of transcription; condensed chromosome; double-strand break repair; heart morphogenesis; histone acetyl-lysine binding; histone kinase activity; non-membrane spanning protein tyrosine kinase activity; nuclear replication fork; nucleus; protein tyrosine kinase activity; transcription, DNA-dependent; vitamin D receptor activator activity; zinc ion binding",PF00439;PF00628;PF10537;PF15612;PF15613;,2.00E-42,CHOYP_BAZ1B.1.1,1.00E-80,ruditapes_c19053,,,,,BAZ1B_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin remodeling [GO:0006338]; double-strand break repair [GO:0006302]; heart morphogenesis [GO:0003007]; histone phosphorylation [GO:0016572]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144191_c0_seq11,4040,42.2277,0.53368564,0,0,,0,Q148N0,"2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)","2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)",GO:0006096; GO:0005759; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrial matrix; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF16078;PF00676;PF16870;PF02779;,,,,,,,,,ODO1_BOVIN,Bos taurus (Bovine),cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099] comp144191_c0_seq12,3542,42.7724,0.55088047,0,0,,0,Q59106,2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase),2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase),GO:0006096; GO:0004591; GO:0030976; GO:0006099,glycolysis; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF16078;PF00676;PF16870;PF02779;,0,CHOYP_ODO1.2.2,,,,,,,ODO1_CUPNH,Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha),glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] comp144191_c0_seq2,2082,46.0134,0.52954931,0,0,,0,Q148N0,"2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)","2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)",GO:0006096; GO:0005759; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrial matrix; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF16078;PF00676;PF16870;PF02779;,,,,,,,,,ODO1_BOVIN,Bos taurus (Bovine),cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099] comp144191_c0_seq4,3560,42.7247,0.54960455,0,0,,0,Q23629,"Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial (EC 1.2.4.2)","Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial (EC 1.2.4.2)",GO:0006096; GO:0005739; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrion; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF00676;PF16870;PF02779;,0,CHOYP_ODO1.2.2,,,,,,,DHTK1_CAEEL,Caenorhabditis elegans,glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] comp144191_c0_seq5,1903,46.0326,0.55022267,0,0,,3.00E-06,O13366,"Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)","Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)",GO:0006096; GO:0005759; GO:0004739,glycolysis; mitochondrial matrix; pyruvate dehydrogenase (acetyl-transferring) activity,PF00676;,4.00E-12,CHOYP_ODO1.1.2,,,,,,,ODPA_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]; pseudohyphal growth [GO:0007124] comp144191_c0_seq6,4726,41.3034,0.55075036,0,0,,0,Q148N0,"2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)","2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)",GO:0006096; GO:0005759; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrial matrix; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF16078;PF00676;PF16870;PF02779;,,,,,,,,,ODO1_BOVIN,Bos taurus (Bovine),cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099] comp144191_c0_seq7,2660,44.4361,0.55833954,0,0,,,,,,,,,,,2.00E-34,ruditapes_c15295,,,,,,, comp144191_c0_seq8,4708,41.3127,0.5524838,11,0,,0,Q148N0,"2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)","2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)",GO:0006096; GO:0005759; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrial matrix; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF16078;PF00676;PF16870;PF02779;,,,,,,,,,ODO1_BOVIN,Bos taurus (Bovine),cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099] comp144191_c0_seq9,3739,42.8724,0.53618302,0,0,,1.00E-11,P86231,"2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase) (Fragments)","2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase) (Fragments)",GO:0006096; GO:0005759; GO:0004591; GO:0030976; GO:0006099,glycolysis; mitochondrial matrix; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,,0,CHOYP_ODO1.2.2,,,,,,,ODO1_MESAU,Mesocricetus auratus (Golden hamster),glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] comp144192_c0_seq2,3002,35.0766,0.76684842,45,43,,,,,,,,,2.00E-18,CHOYP_contig_048420,,,,,,,,, comp144193_c2_seq1,2686,39.8734,0.39863658,24,41,,2.00E-72,Q5TYV4,Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction),Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction),GO:0030154; GO:0005737; GO:0016023; GO:0005769; GO:0061008; GO:0005770; GO:0015031; GO:0055037; GO:0006355; GO:0007283; GO:0006351,"cell differentiation; cytoplasm; cytoplasmic membrane-bounded vesicle; early endosome; hepaticobiliary system development; late endosome; protein transport; recycling endosome; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF04840;,,,,,,,,,SPE39_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell differentiation [GO:0030154]; hepaticobiliary system development [GO:0061008]; intracellular protein transport [GO:0006886]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144194_c0_seq1,2486,27.4336,0.57765075,82,315,,2.00E-24,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,8.00E-33,ruditapes_c19911,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp144194_c0_seq2,2011,27.4988,0.68474806,5,31,,4.00E-30,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp144194_c0_seq3,558,29.7491,0.48750157,1,10,,2.00E-07,Q03274,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00078;,,,,,,,,,PO22_POPJA,Popillia japonica (Japanese beetle), comp144195_c0_seq1,2458,44.2229,0.62913954,369,701,,7.00E-76,Q02241,Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1),GO:0005524; GO:0019886; GO:0007596; GO:0097149; GO:0005813; GO:0000910; GO:0005829; GO:0045171; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018; GO:0030496; GO:0000022; GO:0005654; GO:0032467; GO:0051256,ATP binding; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; centralspindlin complex; centrosome; cytokinesis; cytosol; intercellular bridge; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement; midbody; mitotic spindle elongation; nucleoplasm; positive regulation of cytokinesis; spindle midzone assembly involved in mitosis,PF00225;PF16540;,2.00E-75,CHOYP_LOC373240.1.1,,,,,,,KIF23_HUMAN,Homo sapiens (Human),"actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp144195_c0_seq2,764,46.8586,0.70401872,5,11,,,,,,,,,3.00E-22,CHOYP_LOC373240.1.1,,,,,,,,, comp144196_c0_seq1,3465,45.7143,0.42142855,106,13,,,,,,,,,3.00E-22,CHOYP_RN213.3.13,,,,,,,,, comp144196_c0_seq2,3715,45.1413,0.36032606,22,14,,2.00E-113,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,4.00E-34,CHOYP_RN213.8.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144196_c0_seq5,2294,45.2049,0.32567056,0,0,,,,,,,,,8.00E-22,CHOYP_RN213.6.13,,,,,,,,, comp144196_c0_seq8,2859,44.4561,0.30546452,0,0,,1.00E-73,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,2.00E-18,CHOYP_RN213.8.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144197_c1_seq3,872,39.1055,0.30471244,0,27,,,,,,,,,5.00E-13,CHOYP_contig_024093,,,,,,,,, comp144197_c1_seq5,324,31.1728,0.65156996,8,15,,,,,,,,,2.00E-13,CHOYP_contig_024093,,,,,,,,, comp144197_c1_seq6,337,34.1246,0.716108,0,9,,,,,,,,,6.00E-13,CHOYP_contig_017664,,,,,,,,, comp144198_c0_seq1,1505,35.4153,0.7211631,458,764,,,,,,,,,9.00E-13,CHOYP_contig_032397,,,,,,,,, comp144198_c0_seq2,1178,36.163,0.77967652,119,248,,5.00E-11,Q8N2A0,Putative uncharacterized protein encoded by LINC00269,Putative uncharacterized protein encoded by LINC00269,,,,9.00E-18,CHOYP_RN7SL2.1.1,,,,,,,CX062_HUMAN,Homo sapiens (Human), comp144200_c1_seq1,3912,31.135,0.57172779,27,1101,,7.00E-07,Q28024,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Gamma-S1),Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Gamma-S1),GO:0007186; GO:0005834; GO:0004871,G-protein coupled receptor signaling pathway; heterotrimeric G-protein complex; signal transducer activity,PF00631;,,,,,,,,,GBG12_BOVIN,Bos taurus (Bovine),G-protein coupled receptor signaling pathway [GO:0007186] comp144200_c1_seq3,3814,31.463,0.57398635,18,218,,7.00E-07,Q28024,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Gamma-S1),Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Gamma-S1),GO:0007186; GO:0005834; GO:0004871,G-protein coupled receptor signaling pathway; heterotrimeric G-protein complex; signal transducer activity,PF00631;,,,1.00E-19,ruditapes_c12262,,,,,GBG12_BOVIN,Bos taurus (Bovine),G-protein coupled receptor signaling pathway [GO:0007186] comp144201_c0_seq2,2703,36.8849,0.39562374,140,802,,7.00E-92,Q9BTV4,Transmembrane protein 43 (Protein LUMA),Transmembrane protein 43 (Protein LUMA),GO:0005794; GO:0005783; GO:0016021; GO:0005637,Golgi apparatus; endoplasmic reticulum; integral to membrane; nuclear inner membrane,PF07787;,1.00E-27,CHOYP_BRAFLDRAFT_57622.1.2,,,,,,,TMM43_HUMAN,Homo sapiens (Human),nuclear membrane organization [GO:0071763] comp144203_c0_seq2,1877,35.4822,0.44324631,13,55,,5.00E-36,P0CG11,Chromosome transmission fidelity protein 8 homolog,Chromosome transmission fidelity protein 8 homolog,GO:0003677; GO:0006260; GO:0007049; GO:0005634,DNA binding; DNA replication; cell cycle; nucleus,PF09696;,,,2.00E-51,ruditapes_c19669,,,,,CTF8_BOVIN,Bos taurus (Bovine),DNA replication [GO:0006260]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] comp144205_c1_seq1,1645,43.6474,0.47373556,194,133,,0,Q9EPL8,Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7),Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7),GO:0005794; GO:0042393; GO:0005634; GO:0006606,Golgi apparatus; histone binding; nucleus; protein import into nucleus,PF08506;PF03810;,0,CHOYP_IPO7.1.1,,,,,,,IPO7_MOUSE,Mus musculus (Mouse),innate immune response [GO:0045087]; protein import into nucleus [GO:0006606]; signal transduction [GO:0007165] comp144205_c1_seq2,842,42.8741,0.54340429,0,0,,,,,,,,,,,9.00E-14,ruditapes_c10024,,,,,,, comp144205_c1_seq3,944,42.4788,0.54094137,9,0,,7.00E-15,Q9XZU1,Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein homolog) (Importin-alpha re-exporter),Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein homolog) (Importin-alpha re-exporter),GO:0005737; GO:0022008; GO:0005634; GO:0006909; GO:0051533; GO:0006611,cytoplasm; neurogenesis; nucleus; phagocytosis; positive regulation of NFAT protein import into nucleus; protein export from nucleus,PF03378;PF08506;PF03810;,,,,,,,,,XPO2_DROME,Drosophila melanogaster (Fruit fly),neurogenesis [GO:0022008]; phagocytosis [GO:0006909]; positive regulation of NFAT protein import into nucleus [GO:0051533]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606] comp144206_c0_seq2,1959,37.9786,0.47599435,99,343,,3.00E-116,Q16698,"2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH])","2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)",GO:0008670; GO:0070402; GO:0006635; GO:0005759; GO:0005634; GO:0016651; GO:0051289,"2,4-dienoyl-CoA reductase (NADPH) activity; NADPH binding; fatty acid beta-oxidation; mitochondrial matrix; nucleus; oxidoreductase activity, acting on NAD(P)H; protein homotetramerization",,2.00E-86,CHOYP_NEMVEDRAFT_V1G235656.1.1,,,,,,,DECR_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289] comp144207_c1_seq2,2996,43.1909,0.60626384,32,269,,4.00E-10,Q9Y6Q3,Zinc finger protein 37 homolog (Zfp-37),Zinc finger protein 37 homolog (Zfp-37),GO:0003677; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZFP37_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144207_c1_seq3,3001,42.7191,0.60388789,0,0,,4.00E-69,O54941,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57),GO:0003677; GO:0008080; GO:0003723; GO:0016514; GO:0006338; GO:0071565; GO:0045892; GO:0007399; GO:0071564; GO:0006337; GO:0017053,"DNA binding; N-acetyltransferase activity; RNA binding; SWI/SNF complex; chromatin remodeling; nBAF complex; negative regulation of transcription, DNA-dependent; nervous system development; npBAF complex; nucleosome disassembly; transcriptional repressor complex",PF00505;,3.00E-85,CHOYP_LOC100651274.1.1,,,,,,,SMCE1_MOUSE,Mus musculus (Mouse),"ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; nucleosome disassembly [GO:0006337]" comp144207_c1_seq6,1393,39.5549,0.71855707,0,0,,5.00E-20,G5EBU4,Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),GO:0007411; GO:0046872; GO:0000122; GO:0005634; GO:0045773; GO:0043565; GO:0003700; GO:0006351,"axon guidance; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of axon extension; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF13912;,,,,,,,,,ZAG1_CAEEL,Caenorhabditis elegans,"axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]" comp144207_c1_seq8,1397,39.7996,0.70726998,0,0,,5.00E-20,G5EBU4,Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1),GO:0007411; GO:0046872; GO:0000122; GO:0005634; GO:0045773; GO:0043565; GO:0003700; GO:0006351,"axon guidance; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of axon extension; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF13912;,,,,,,,,,ZAG1_CAEEL,Caenorhabditis elegans,"axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]" comp144209_c0_seq1,2828,45.6153,0.44217812,534,384,,0,I0IUP3,DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8),DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8),GO:0005524; GO:0003677; GO:0006260; GO:0097362; GO:0000724; GO:0004386; GO:0005634,ATP binding; DNA binding; DNA replication; MCM8-MCM9 complex; double-strand break repair via homologous recombination; helicase activity; nucleus,PF00493;,0,CHOYP_LOC100377194.2.2,,,,,,,MCM8_CHICK,Gallus gallus (Chicken),cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; male gamete generation [GO:0048232] comp144209_c0_seq2,459,49.4553,0.32364131,0,0,,,,,,,,,4.00E-17,CHOYP_BRAFLDRAFT_123986.1.1,,,,,,,,, comp144210_c0_seq3,3598,46.6092,0.54454715,980,35,,0,Q6ZR08,"Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)","Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;,0,CHOYP_DNAH12.2.3,2.00E-47,ruditapes_c10161,,,,,DYH12_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144210_c0_seq4,670,43.8806,0.43480773,13,0,,5.00E-13,Q6ZR08,"Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)","Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;,1.00E-13,CHOYP_DNAH12.2.3,,,,,,,DYH12_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144211_c0_seq13,4743,38.3513,0.32254478,289,113,,8.00E-60,Q8NA31,Coiled-coil domain-containing protein 79,Telomere repeats-binding bouquet formation protein 1 (Coiled-coil domain-containing protein 79),GO:0003677; GO:0003682,DNA binding; chromatin binding,PF00249;,,,,,,,,,CCD79_HUMAN,Homo sapiens (Human),meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129] comp144211_c0_seq2,1037,39.2478,0.2568038,0,0,,2.00E-53,Q8NA31,Coiled-coil domain-containing protein 79,Telomere repeats-binding bouquet formation protein 1 (Coiled-coil domain-containing protein 79),GO:0003677; GO:0003682,DNA binding; chromatin binding,PF00249;,,,,,,,,,CCD79_HUMAN,Homo sapiens (Human),meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129] comp144212_c1_seq7,575,33.3913,0.18782666,5,0,,1.00E-11,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144213_c0_seq1,2978,38.1464,0.66883708,623,201,,1.00E-63,Q7T0L6,Cyclin-F,Cyclin-F,GO:0019005; GO:0031146; GO:0051301; GO:0005814; GO:0007067; GO:0010826; GO:0005634; GO:0016567,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; centriole; mitosis; negative regulation of centrosome duplication; nucleus; protein ubiquitination,PF02984;PF00134;PF00646;,,,,,,,,,CCNF_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of centrosome duplication [GO:0010826]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp144213_c1_seq1,900,44,0.5316459,223,66,,,,,,,,,4.00E-52,CHOYP_LOC100374550.1.1,,,,,,,,, comp144214_c0_seq2,4476,36.7962,0.46954927,459,592,,0,Q9ULT8,E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),GO:0005737; GO:0046872; GO:0001843; GO:0005634; GO:0042787; GO:0004842,cytoplasm; metal ion binding; neural tube closure; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12796;PF00632;PF06701;PF07738;,1.00E-130,CHOYP_HECD1.1.1,,,,,,,HECD1_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144214_c0_seq3,4272,36.8446,0.47654817,274,330,,0,Q9ULT8,E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1),GO:0005737; GO:0046872; GO:0001843; GO:0005634; GO:0042787; GO:0004842,cytoplasm; metal ion binding; neural tube closure; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12796;PF00632;PF06701;PF07738;,1.00E-130,CHOYP_HECD1.1.1,,,,,,,HECD1_HUMAN,Homo sapiens (Human),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144216_c1_seq1,4323,39.0007,0.47005929,9,8,,6.00E-12,Q0DZT4,Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C19_ORYSJ,Oryza sativa subsp. japonica (Rice), comp144216_c1_seq11,4265,39.0856,0.47501903,0,7,,6.00E-12,Q0DZT4,Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,1.00E-41,CHOYP_Y0417.2.2,,,,,,,P2C19_ORYSJ,Oryza sativa subsp. japonica (Rice), comp144216_c1_seq12,1430,42.5175,0.49909344,0,0,,6.00E-20,Q9LME4,Probable protein phosphatase 2C 9 (AtPP2C09) (EC 3.1.3.16) (Phytochrome-associated protein phosphatase 2C) (PAPP2C),Probable protein phosphatase 2C 9 (AtPP2C09) (EC 3.1.3.16) (Phytochrome-associated protein phosphatase 2C) (PAPP2C),GO:0008152; GO:0046872; GO:0005634; GO:0004721,metabolic process; metal ion binding; nucleus; phosphoprotein phosphatase activity,PF00481;,4.00E-29,CHOYP_Y0417.1.2,,,,,,,P2C09_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp144216_c1_seq14,2309,39.1945,0.51389404,0,0,,1.00E-73,Q7K4Q5,Probable protein phosphatase CG10417 (EC 3.1.3.16),Probable protein phosphatase CG10417 (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,7.00E-42,CHOYP_Y0417.2.2,,,,,,,Y0417_DROME,Drosophila melanogaster (Fruit fly),protein dephosphorylation [GO:0006470] comp144216_c1_seq15,4297,39.0505,0.4643929,0,0,,5.00E-12,Q0DZT4,Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C19_ORYSJ,Oryza sativa subsp. japonica (Rice), comp144216_c1_seq16,3235,39.5672,0.48765423,0,0,,1.00E-73,Q7K4Q5,Probable protein phosphatase CG10417 (EC 3.1.3.16),Probable protein phosphatase CG10417 (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,Y0417_DROME,Drosophila melanogaster (Fruit fly),protein dephosphorylation [GO:0006470] comp144216_c1_seq17,3318,39.4515,0.47656658,0,0,,5.00E-61,P49595,Probable protein phosphatase 2C F42G9.1 (PP2C) (EC 3.1.3.16),Probable protein phosphatase 2C F42G9.1 (PP2C) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,PP2C1_CAEEL,Caenorhabditis elegans, comp144216_c1_seq3,2368,39.0625,0.50291425,0,0,,2.00E-73,Q7K4Q5,Probable protein phosphatase CG10417 (EC 3.1.3.16),Probable protein phosphatase CG10417 (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,7.00E-42,CHOYP_Y0417.2.2,,,,,,,Y0417_DROME,Drosophila melanogaster (Fruit fly),protein dephosphorylation [GO:0006470] comp144216_c1_seq4,698,43.1232,0.53885402,0,0,,2.00E-21,Q9LME4,Probable protein phosphatase 2C 9 (AtPP2C09) (EC 3.1.3.16) (Phytochrome-associated protein phosphatase 2C) (PAPP2C),Probable protein phosphatase 2C 9 (AtPP2C09) (EC 3.1.3.16) (Phytochrome-associated protein phosphatase 2C) (PAPP2C),GO:0008152; GO:0046872; GO:0005634; GO:0004721,metabolic process; metal ion binding; nucleus; phosphoprotein phosphatase activity,PF00481;,,,,,,,,,P2C09_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp144216_c1_seq5,2344,39.0785,0.50900812,0,0,,1.00E-73,Q7K4Q5,Probable protein phosphatase CG10417 (EC 3.1.3.16),Probable protein phosphatase CG10417 (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,Y0417_DROME,Drosophila melanogaster (Fruit fly),protein dephosphorylation [GO:0006470] comp144216_c1_seq6,1915,42.4021,0.47738268,0,0,,,,,,,,,6.00E-29,CHOYP_Y0417.1.2,,,,,,,,, comp144216_c1_seq7,2285,39.2123,0.52033035,0,0,,1.00E-53,Q653S3,Probable protein phosphatase 2C 70 (OsPP2C70) (EC 3.1.3.16),Probable protein phosphatase 2C 70 (OsPP2C70) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,7.00E-42,CHOYP_Y0417.2.2,,,,,,,P2C70_ORYSJ,Oryza sativa subsp. japonica (Rice), comp144216_c1_seq9,4180,39.0191,0.466297,0,0,,5.00E-12,Q0DZT4,Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16),GO:0046872; GO:0006470; GO:0004722,metal ion binding; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,P2C19_ORYSJ,Oryza sativa subsp. japonica (Rice), comp144220_c0_seq2,4457,30.626,0.39650222,487,2995,,6.00E-88,O77210,Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein),Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein),GO:0005737; GO:0006417; GO:0003743,cytoplasm; regulation of translation; translation initiation factor activity,PF01652;,5.00E-91,CHOYP_IF4E.1.1,2.00E-107,ruditapes_c1058,,,,,IF4E_APLCA,Aplysia californica (California sea hare),regulation of translation [GO:0006417] comp144223_c0_seq1,2125,39.2941,0.50436293,2,4,,9.00E-47,Q54EC2,Probable ATP-dependent RNA helicase ddx55 (EC 3.6.4.13) (DEAD box protein 55),Probable ATP-dependent RNA helicase ddx55 (EC 3.6.4.13) (DEAD box protein 55),GO:0005524; GO:0008026; GO:0003723; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus; rRNA processing,PF00270;PF13959;PF00271;,,,,,,,,,DDX55_DICDI,Dictyostelium discoideum (Slime mold),RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364] comp144223_c0_seq2,3956,40.1416,0.39421473,5,31,,0,Q8K363,ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18),ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18),GO:0005524; GO:0008026; GO:0003723; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus,PF00270;PF13959;PF00271;,0,CHOYP_DDX18.2.2,,,,,,,DDX18_MOUSE,Mus musculus (Mouse),RNA secondary structure unwinding [GO:0010501] comp144223_c0_seq3,4160,39.7115,0.39588985,93,151,,3.00E-43,Q9FVV4,DEAD-box ATP-dependent RNA helicase 55 (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase 55 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0008266,ATP binding; ATP-dependent helicase activity; poly(U) RNA binding,PF00270;PF13959;PF00271;,,,,,,,,,RH55_ARATH,Arabidopsis thaliana (Mouse-ear cress),RNA secondary structure unwinding [GO:0010501] comp144223_c0_seq4,4140,39.9275,0.40574174,34,46,,0,Q8K363,ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18),ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18),GO:0005524; GO:0008026; GO:0003723; GO:0005730,ATP binding; ATP-dependent helicase activity; RNA binding; nucleolus,PF00270;PF13959;PF00271;,0,CHOYP_DDX18.2.2,,,,,,,DDX18_MOUSE,Mus musculus (Mouse),RNA secondary structure unwinding [GO:0010501] comp144225_c2_seq6,4001,40.7148,0.35216048,11,4,,9.00E-49,A9CB34,Protein SFI1 homolog,Protein SFI1 homolog,GO:0005814; GO:0010923; GO:0019902,centriole; negative regulation of phosphatase activity; phosphatase binding,,,,,,,,,,SFI1_PAPAN,Papio anubis (Olive baboon),negative regulation of phosphatase activity [GO:0010923] comp144226_c1_seq2,1690,43.432,0.42455127,183,75,,2.00E-164,Q9HAU5,Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2),Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2),GO:0003723; GO:0005829; GO:0035145; GO:0010467; GO:0001889; GO:0006406; GO:0000184; GO:0031100; GO:0048471,"RNA binding; cytosol; exon-exon junction complex; gene expression; liver development; mRNA export from nucleus; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; organ regeneration; perinuclear region of cytoplasm",PF02854;PF04050;,0,CHOYP_RENT2.1.1,,,,,,,RENT2_HUMAN,Homo sapiens (Human),"liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; organ regeneration [GO:0031100]" comp144226_c1_seq5,1629,36.3413,0.60500502,192,74,,,,,,,,,1.00E-31,CHOYP_RENT2.1.1,,,,,,,,, comp144227_c0_seq1,903,46.8439,0.6324254,42,644,,3.00E-104,A3KMP2,Tetratricopeptide repeat protein 38 (TPR repeat protein 38),Tetratricopeptide repeat protein 38 (TPR repeat protein 38),,,,1.00E-21,CHOYP_LOC100028654.1.1,,,,,,,TTC38_MOUSE,Mus musculus (Mouse), comp144227_c0_seq2,1068,37.5468,0.93100012,144,1439,,,,,,,,,,,2.00E-16,ruditapes_c25195,,,,,,, comp144231_c0_seq1,4126,48.6185,0.48011278,468,152,,3.00E-104,Q7Z6Z7,"E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)","E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)",GO:0003677; GO:0006284; GO:0030154; GO:0005737; GO:0016574; GO:0005634; GO:0006513; GO:0000209; GO:0042787; GO:0004842,DNA binding; base-excision repair; cell differentiation; cytoplasm; histone ubiquitination; nucleus; protein monoubiquitination; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;,2.00E-38,CHOYP_HUWE1.1.2,1.00E-65,ruditapes_c21445,,,,,HUWE1_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144231_c0_seq2,1780,47.6404,0.64523611,522,191,,0,Q7Z6Z7,"E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)","E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)",GO:0003677; GO:0006284; GO:0030154; GO:0005737; GO:0016574; GO:0005634; GO:0006513; GO:0000209; GO:0042787; GO:0004842,DNA binding; base-excision repair; cell differentiation; cytoplasm; histone ubiquitination; nucleus; protein monoubiquitination; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;,0,CHOYP_HUWE1.2.2,,,,,,,HUWE1_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144231_c1_seq1,497,37.4245,0.40686439,52,45,,1.00E-10,B4F6W9,E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),GO:0006281; GO:0009790; GO:2000780; GO:1901315; GO:0005654; GO:0042787; GO:0006974; GO:0004842,DNA repair; embryo development; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity,PF00632;PF02825;,,,,,,,,,TRIPC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144232_c0_seq1,4426,43.6286,0.46936273,994,1444,,1.00E-28,Q06732,Zinc finger protein 33B (Zinc finger protein 11B) (Zinc finger protein KOX2),Zinc finger protein 33B (Zinc finger protein 11B) (Zinc finger protein KOX2),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN33B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144232_c0_seq3,677,42.0975,0.65892727,0,6,,6.00E-09,Q5RBK0,Gypsy retrotransposon integrase-like protein 1 (GIN-1),Gypsy retrotransposon integrase-like protein 1 (GIN-1),GO:0015074; GO:0003676,DNA integration; nucleic acid binding,,,,,,,,,,GIN1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),DNA integration [GO:0015074] comp144233_c0_seq2,2937,41.2666,0.45797486,51,58,,0,O97593,Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A),Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A),GO:0005524; GO:0006310; GO:0006281; GO:0051301; GO:0003682; GO:0030261; GO:0005737; GO:0000776; GO:0007126; GO:0030893; GO:0007067; GO:0007093; GO:0032876; GO:0005634; GO:0009314; GO:0042770; GO:0007062; GO:0019827,ATP binding; DNA recombination; DNA repair; cell division; chromatin binding; chromosome condensation; cytoplasm; kinetochore; meiosis; meiotic cohesin complex; mitosis; mitotic cell cycle checkpoint; negative regulation of DNA endoreduplication; nucleus; response to radiation; signal transduction in response to DNA damage; sister chromatid cohesion; stem cell maintenance,PF06470;PF02463;,0,CHOYP_LOC100374527.1.1,,,,,,,SMC1A_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]; signal transduction in response to DNA damage [GO:0042770] comp144233_c0_seq3,2904,41.3223,0.46231198,6,10,,0,Q920F6,Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B),Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B),GO:0005524; GO:0003677; GO:0006310; GO:0006281; GO:0030261; GO:0000775; GO:0000800; GO:0007126; GO:0034991; GO:0005654; GO:0007062,"ATP binding; DNA binding; DNA recombination; DNA repair; chromosome condensation; chromosome, centromeric region; lateral element; meiosis; nuclear meiotic cohesin complex; nucleoplasm; sister chromatid cohesion",PF06470;PF02463;,,,,,,,,,SMC1B_MOUSE,Mus musculus (Mouse),meiotic nuclear division [GO:0007126]; sister chromatid cohesion [GO:0007062] comp144233_c0_seq4,927,39.698,0.5403457,226,132,,4.00E-17,P41003,Structural maintenance of chromosomes protein 2 (Cell untimely torn protein 14) (Chromosome segregation protein cut14),Structural maintenance of chromosomes protein 2 (Cell untimely torn protein 14) (Chromosome segregation protein cut14),GO:0005524; GO:0016887; GO:0006310; GO:0006281; GO:0051301; GO:0051304; GO:0000939; GO:0000796; GO:0005737; GO:0007076; GO:0005730; GO:0007062,ATP binding; ATPase activity; DNA recombination; DNA repair; cell division; chromosome separation; condensed chromosome inner kinetochore; condensin complex; cytoplasm; mitotic chromosome condensation; nucleolus; sister chromatid cohesion,PF06470;PF02463;,,,,,,,,,SMC2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp144233_c0_seq7,690,35.6522,0.46460126,1,0,,9.00E-13,O93308,Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A) (xSMC1),Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A) (xSMC1),GO:0005524; GO:0006310; GO:0006281; GO:0051301; GO:0003682; GO:0030261; GO:0000776; GO:0007126; GO:0030893; GO:0007067; GO:0007093; GO:0005634; GO:0009314; GO:0042770; GO:0007062,ATP binding; DNA recombination; DNA repair; cell division; chromatin binding; chromosome condensation; kinetochore; meiosis; meiotic cohesin complex; mitosis; mitotic cell cycle checkpoint; nucleus; response to radiation; signal transduction in response to DNA damage; sister chromatid cohesion,PF06470;PF02463;,1.00E-19,CHOYP_LOC100374527.1.1,,,,,,,SMC1A_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]; signal transduction in response to DNA damage [GO:0042770] comp144234_c0_seq1,2464,41.6396,1.07716381,155,800,,0,H2A0M3,Putative amine oxidase [copper-containing] (EC 1.4.3.-),Putative amine oxidase [copper-containing] (EC 1.4.3.-),GO:0009308; GO:0005507; GO:0005576; GO:0008131; GO:0048038,amine metabolic process; copper ion binding; extracellular region; primary amine oxidase activity; quinone binding,PF01179;,,,2.00E-40,ruditapes_c9567,,,,,AMO_PINMG,Pinctada margaritifera (Black-lipped pearl oyster),amine metabolic process [GO:0009308] comp144236_c0_seq1,3694,42.0141,0.56408243,41,87,,,,,,,,,1.00E-90,CHOYP_NUP205.1.1,,,,,,,,, comp144236_c0_seq2,5376,43.5826,0.53223729,240,510,,0,Q92621,Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205),Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205),GO:0005975; GO:0019221; GO:0015758; GO:0051028; GO:0007077; GO:0031965; GO:0034399; GO:0005643; GO:0051292; GO:0000059; GO:0010827; GO:0044281; GO:0017056; GO:0055085; GO:0016032,"carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore complex assembly; protein import into nucleus, docking; regulation of glucose transport; small molecule metabolic process; structural constituent of nuclear pore; transmembrane transport; viral process",PF11894;,3.00E-89,CHOYP_NUP205.1.1,2.00E-24,ruditapes_c19484,,,,,NU205_HUMAN,Homo sapiens (Human),"gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]" comp144236_c0_seq3,3674,41.7801,0.55452299,4,142,,3.00E-176,Q92621,Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205),Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205),GO:0005975; GO:0019221; GO:0015758; GO:0051028; GO:0007077; GO:0031965; GO:0034399; GO:0005643; GO:0051292; GO:0000059; GO:0010827; GO:0044281; GO:0017056; GO:0055085; GO:0016032,"carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore complex assembly; protein import into nucleus, docking; regulation of glucose transport; small molecule metabolic process; structural constituent of nuclear pore; transmembrane transport; viral process",PF11894;,,,4.00E-38,ruditapes2_c1823,,,,,NU205_HUMAN,Homo sapiens (Human),"gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]" comp144238_c5_seq2,2958,37.8634,0.5023995,1099,2921,,5.00E-39,Q1LUA6,Triple functional domain protein (EC 2.7.11.1),Triple functional domain protein (EC 2.7.11.1),GO:0005524; GO:0005089; GO:0005737; GO:0005543; GO:0004674; GO:0035023,ATP binding; Rho guanyl-nucleotide exchange factor activity; cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction,PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,4.00E-52,CHOYP_TRIO.1.1,,,,,,,TRIO_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of Rho protein signal transduction [GO:0035023] comp144238_c5_seq3,1196,40.0502,0.60710456,11,2,,,,,,,,,3.00E-17,CHOYP_KALRN.2.2,,,,,,,,, comp144239_c2_seq3,5243,34.7892,0.78415629,10,61,,1.00E-40,Q6P3Z3,THAP domain-containing protein 4,THAP domain-containing protein 4,GO:0003677; GO:0046872,DNA binding; metal ion binding,PF08768;PF05485;,,,,,,,,,THAP4_MOUSE,Mus musculus (Mouse), comp144239_c2_seq6,5240,34.9427,0.79661113,14,266,,1.00E-40,Q6P3Z3,THAP domain-containing protein 4,THAP domain-containing protein 4,GO:0003677; GO:0046872,DNA binding; metal ion binding,PF08768;PF05485;,,,,,,,,,THAP4_MOUSE,Mus musculus (Mouse), comp144243_c0_seq1,1439,41.1397,0.54658411,367,1330,,0,Q803X1,Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1),Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1),GO:0005524; GO:0005829; GO:0000049; GO:0034227; GO:0002098; GO:0016740,ATP binding; cytosol; tRNA binding; tRNA thio-modification; tRNA wobble uridine modification; transferase activity,PF01171;PF16503;,0,CHOYP_BRAFLDRAFT_127518.1.1,3.00E-92,ruditapes_c7299,,,,,CTU1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] comp144243_c1_seq2,1395,32.1864,0.7227691,0,0,,,,,,,,,,,6.00E-25,ruditapes_c9745,,,,,,, comp144243_c1_seq3,1382,29.3054,0.58334191,29,55,,,,,,,,,,,1.00E-15,ruditapes_c14826,,,,,,, comp144243_c1_seq6,1570,31.2739,0.70824874,0,20,,,,,,,,,,,3.00E-11,ruditapes_c18681,,,,,,, comp144244_c0_seq1,4883,41.6547,0.31689471,5,1148,female>male,2.00E-07,P45745,Dimodular nonribosomal peptide synthase,Dimodular nonribosomal peptide synthase,GO:0009058; GO:0016788; GO:0016874; GO:0031177,"biosynthetic process; hydrolase activity, acting on ester bonds; ligase activity; phosphopantetheine binding",PF00501;PF13193;PF00668;PF00550;PF00975;,,,,,,,,,DHBF_BACSU,Bacillus subtilis (strain 168),biosynthetic process [GO:0009058] comp144244_c0_seq2,4895,41.6752,0.32051788,0,1146,female,2.00E-27,P49327,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0070402; GO:0004313; GO:0004314; GO:0006084; GO:0071353; GO:0005829; GO:0008144; GO:0006112; GO:0047117; GO:0004319; GO:0006633; GO:0006631; GO:0004312; GO:0042587; GO:0035338; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0015939; GO:0005886; GO:0031325; GO:0019432; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; NADPH binding; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; acetyl-CoA metabolic process; cellular response to interleukin-4; cytosol; drug binding; energy reserve metabolic process; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; fatty acid metabolic process; fatty acid synthase activity; glycogen granule; long-chain fatty-acyl-CoA biosynthetic process; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; pantothenate metabolic process; plasma membrane; positive regulation of cellular metabolic process; triglyceride biosynthetic process; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,,,,,,,,,FAS_HUMAN,Homo sapiens (Human),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]; pantothenate metabolic process [GO:0015939]; positive regulation of cellular metabolic process [GO:0031325] comp144248_c0_seq1,6378,39.1659,0.51717955,4,0,,0,P55201,Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140),Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140),GO:0003677; GO:0070776; GO:0005737; GO:0043966; GO:0005886; GO:0045893; GO:0006351; GO:0008270,"DNA binding; MOZ/MORF histone acetyltransferase complex; cytoplasm; histone H3 acetylation; plasma membrane; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF10513;PF00855;,0,CHOYP_LOC100372837.2.2,,,,,,,BRPF1_HUMAN,Homo sapiens (Human),"histone H3 acetylation [GO:0043966]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp144248_c0_seq3,2270,34.141,0.49302588,3,29,,,,,,,,,1.00E-94,CHOYP_BRPF1.1.1,,,,,,,,, comp144248_c0_seq5,6377,39.125,0.51840308,13,9,,0,P55201,Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140),Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140),GO:0003677; GO:0070776; GO:0005737; GO:0043966; GO:0005886; GO:0045893; GO:0006351; GO:0008270,"DNA binding; MOZ/MORF histone acetyltransferase complex; cytoplasm; histone H3 acetylation; plasma membrane; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF10513;PF00855;,0,CHOYP_LOC100372837.2.2,,,,,,,BRPF1_HUMAN,Homo sapiens (Human),"histone H3 acetylation [GO:0043966]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]" comp144250_c0_seq1,6066,45.4995,0.44283487,0,0,,1.00E-38,Q6PA26,Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),GO:0071818; GO:0007420; GO:0016568; GO:0009790; GO:0018393; GO:0042771; GO:0070059; GO:0001822; GO:0030324; GO:0032435; GO:0005634; GO:0031593; GO:0070628; GO:0050821; GO:0043022; GO:0007283; GO:0007130; GO:0071816; GO:0006810; GO:0006511,BAT3 complex; brain development; chromatin modification; embryo development; internal peptidyl-lysine acetylation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; kidney development; lung development; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleus; polyubiquitin binding; proteasome binding; protein stabilization; ribosome binding; spermatogenesis; synaptonemal complex assembly; tail-anchored membrane protein insertion into ER membrane; transport; ubiquitin-dependent protein catabolic process,PF12057;PF00240;,3.00E-38,CHOYP_BAG6A.1.1,,,,,,,BAG6B_XENLA,Xenopus laevis (African clawed frog),brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144250_c0_seq11,6674,44.3812,0.4565445,0,0,,1.00E-38,Q6PA26,Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),GO:0071818; GO:0007420; GO:0016568; GO:0009790; GO:0018393; GO:0042771; GO:0070059; GO:0001822; GO:0030324; GO:0032435; GO:0005634; GO:0031593; GO:0070628; GO:0050821; GO:0043022; GO:0007283; GO:0007130; GO:0071816; GO:0006810; GO:0006511,BAT3 complex; brain development; chromatin modification; embryo development; internal peptidyl-lysine acetylation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; kidney development; lung development; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleus; polyubiquitin binding; proteasome binding; protein stabilization; ribosome binding; spermatogenesis; synaptonemal complex assembly; tail-anchored membrane protein insertion into ER membrane; transport; ubiquitin-dependent protein catabolic process,PF12057;PF00240;,,,,,,,,,BAG6B_XENLA,Xenopus laevis (African clawed frog),brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144250_c0_seq12,6133,45.3286,0.44129703,0,0,,6.00E-07,B0KWT6,Ubiquitin-like protein 4A,Ubiquitin-like protein 4A,GO:0071818; GO:0071816; GO:0006810,BAT3 complex; tail-anchored membrane protein insertion into ER membrane; transport,PF00240;,3.00E-38,CHOYP_BAG6A.1.1,,,,,,,UBL4A_CALJA,Callithrix jacchus (White-tufted-ear marmoset),tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810] comp144250_c0_seq13,6603,44.298,0.45396043,0,0,,1.00E-38,Q6PA26,Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),GO:0071818; GO:0007420; GO:0016568; GO:0009790; GO:0018393; GO:0042771; GO:0070059; GO:0001822; GO:0030324; GO:0032435; GO:0005634; GO:0031593; GO:0070628; GO:0050821; GO:0043022; GO:0007283; GO:0007130; GO:0071816; GO:0006810; GO:0006511,BAT3 complex; brain development; chromatin modification; embryo development; internal peptidyl-lysine acetylation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; kidney development; lung development; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleus; polyubiquitin binding; proteasome binding; protein stabilization; ribosome binding; spermatogenesis; synaptonemal complex assembly; tail-anchored membrane protein insertion into ER membrane; transport; ubiquitin-dependent protein catabolic process,PF12057;PF00240;,,,,,,,,,BAG6B_XENLA,Xenopus laevis (African clawed frog),brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144250_c0_seq14,6590,44.2944,0.45490729,0,0,,7.00E-07,B0KWT6,Ubiquitin-like protein 4A,Ubiquitin-like protein 4A,GO:0071818; GO:0071816; GO:0006810,BAT3 complex; tail-anchored membrane protein insertion into ER membrane; transport,PF00240;,3.00E-38,CHOYP_BAG6A.1.1,,,,,,,UBL4A_CALJA,Callithrix jacchus (White-tufted-ear marmoset),tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810] comp144250_c0_seq4,6049,45.2471,0.43934452,0,0,,1.00E-38,Q6PA26,Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),GO:0071818; GO:0007420; GO:0016568; GO:0009790; GO:0018393; GO:0042771; GO:0070059; GO:0001822; GO:0030324; GO:0032435; GO:0005634; GO:0031593; GO:0070628; GO:0050821; GO:0043022; GO:0007283; GO:0007130; GO:0071816; GO:0006810; GO:0006511,BAT3 complex; brain development; chromatin modification; embryo development; internal peptidyl-lysine acetylation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; kidney development; lung development; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleus; polyubiquitin binding; proteasome binding; protein stabilization; ribosome binding; spermatogenesis; synaptonemal complex assembly; tail-anchored membrane protein insertion into ER membrane; transport; ubiquitin-dependent protein catabolic process,PF12057;PF00240;,3.00E-38,CHOYP_BAG6A.1.1,,,,,,,BAG6B_XENLA,Xenopus laevis (African clawed frog),brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144250_c0_seq8,5982,45.4196,0.44091578,18,9,,1.00E-38,Q6PA26,Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B),GO:0071818; GO:0007420; GO:0016568; GO:0009790; GO:0018393; GO:0042771; GO:0070059; GO:0001822; GO:0030324; GO:0032435; GO:0005634; GO:0031593; GO:0070628; GO:0050821; GO:0043022; GO:0007283; GO:0007130; GO:0071816; GO:0006810; GO:0006511,BAT3 complex; brain development; chromatin modification; embryo development; internal peptidyl-lysine acetylation; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; kidney development; lung development; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleus; polyubiquitin binding; proteasome binding; protein stabilization; ribosome binding; spermatogenesis; synaptonemal complex assembly; tail-anchored membrane protein insertion into ER membrane; transport; ubiquitin-dependent protein catabolic process,PF12057;PF00240;,3.00E-38,CHOYP_BAG6A.1.1,,,,,,,BAG6B_XENLA,Xenopus laevis (African clawed frog),brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144250_c0_seq9,6687,44.3846,0.45560757,0,0,,7.00E-07,B0KWT6,Ubiquitin-like protein 4A,Ubiquitin-like protein 4A,GO:0071818; GO:0071816; GO:0006810,BAT3 complex; tail-anchored membrane protein insertion into ER membrane; transport,PF00240;,,,,,,,,,UBL4A_CALJA,Callithrix jacchus (White-tufted-ear marmoset),tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810] comp144251_c0_seq1,3393,40.9372,0.59913003,173,312,,6.00E-90,P30666,DNA replication licensing factor mcm3 (EC 3.6.4.12) (Minichromosome maintenance protein 3),DNA replication licensing factor mcm3 (EC 3.6.4.12) (Minichromosome maintenance protein 3),GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006270; GO:0031261; GO:0042555; GO:0005829; GO:0051097; GO:0005656; GO:0043596,ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication initiation; DNA replication preinitiation complex; MCM complex; cytosol; negative regulation of helicase activity; nuclear pre-replicative complex; nuclear replication fork,PF00493;PF14551;,,,,,,,,,MCM3_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mitotic DNA replication initiation [GO:1902975]; negative regulation of helicase activity [GO:0051097] comp144251_c0_seq2,3393,41.0256,0.62502647,30,70,,0,Q6NX31,DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7),DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7),GO:0005524; GO:0006200; GO:0003677; GO:0003678; GO:0006270; GO:0006268; GO:0042555; GO:0007049; GO:0000785; GO:0046872; GO:0005634; GO:0030174,ATP binding; ATP catabolic process; DNA binding; DNA helicase activity; DNA replication initiation; DNA unwinding involved in DNA replication; MCM complex; cell cycle; chromatin; metal ion binding; nucleus; regulation of DNA-dependent DNA replication initiation,PF00493;PF14551;,0,CHOYP_MCM7.1.1,2.00E-92,ruditapes_c23855,2.00E-107,AM237674.p.cg.6,9,,MCM7_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174] comp144254_c0_seq1,2577,46.0225,0.47311847,49,111,,1.00E-127,Q8IZH2,5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog),5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog),GO:0008409; GO:0003677; GO:0005794; GO:0003723; GO:0000932; GO:0005829; GO:0043928; GO:0010467; GO:0071044; GO:0045111; GO:0071028; GO:0090305; GO:0005886; GO:0016075,5'-3' exonuclease activity; DNA binding; Golgi apparatus; RNA binding; cytoplasmic mRNA processing body; cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene expression; histone mRNA catabolic process; intermediate filament cytoskeleton; nuclear mRNA surveillance; nucleic acid phosphodiester bond hydrolysis; plasma membrane; rRNA catabolic process,PF03159;,,,,,,,,,XRN1_HUMAN,Homo sapiens (Human),histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; regulation of mRNA stability [GO:0043488]; rRNA catabolic process [GO:0016075] comp144254_c0_seq3,1672,46.1722,0.49040865,2,0,,,,,,,,,6.00E-22,CHOYP_LOC100369596.1.1,5.00E-21,ruditapes_c13995,,,,,,, comp144254_c0_seq6,2266,46.6019,0.50089477,19,19,,,,,,,,,8.00E-22,CHOYP_LOC100369596.1.1,,,,,,,,, comp144255_c1_seq1,9448,41.956,0.60074119,44,0,,3.00E-37,Q4R3S3,Ankyrin repeat domain-containing protein 7,Ankyrin repeat domain-containing protein 7,,,PF12796;,1.00E-59,CHOYP_LOC100371645.2.2,,,,,,,ANKR7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp144255_c1_seq10,9356,42.0479,0.60665956,0,0,,8.00E-48,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq11,9257,42.0115,0.60727946,14,0,,2.00E-46,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,3.00E-59,CHOYP_ANKRD7.2.3,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq12,5263,38.4382,0.77003192,0,0,,,,,,,,,5.00E-60,CHOYP_LOC100371645.2.2,,,,,,,,, comp144255_c1_seq13,9263,42.0382,0.61105693,0,0,,8.00E-48,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq14,9355,41.9348,0.60787754,0,0,,3.00E-37,Q9H560,Putative ankyrin repeat domain-containing protein 19 (Ankyrin repeat domain-containing protein 19 pseudogene),Putative ankyrin repeat domain-containing protein 19 (Ankyrin repeat domain-containing protein 19 pseudogene),,,PF00023;PF12796;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR19_HUMAN,Homo sapiens (Human), comp144255_c1_seq15,9338,42.0218,0.60849864,0,0,,2.00E-47,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq17,9430,41.9194,0.60536761,0,0,,3.00E-46,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq18,5245,38.3794,0.77487235,0,0,,,,,,,,,5.00E-60,CHOYP_LOC100371645.2.2,,,,,,,,, comp144255_c1_seq2,9337,41.9085,0.60972646,0,0,,3.00E-46,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,3.00E-59,CHOYP_ANKRD7.2.3,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq3,9350,42.0428,0.60473799,0,0,,2.00E-46,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq5,9332,42.006,0.60941198,0,0,,3.00E-46,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq8,8046,41.2627,0.63196859,0,0,,1.00E-47,Q9UPS8,Ankyrin repeat domain-containing protein 26,Ankyrin repeat domain-containing protein 26,GO:0005813,centrosome,PF00023;PF12796;PF12001;,8.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANR26_HUMAN,Homo sapiens (Human), comp144255_c1_seq9,9239,42.0067,0.61098057,0,0,,3.00E-37,Q4R3S3,Ankyrin repeat domain-containing protein 7,Ankyrin repeat domain-containing protein 7,,,PF12796;,9.00E-60,CHOYP_LOC100371645.2.2,,,,,,,ANKR7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp144256_c0_seq1,5304,42.8544,0.51894783,524,1370,,0,Q84UQ1,DEAD-box ATP-dependent RNA helicase 42 (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase 42 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723,ATP binding; ATP-dependent helicase activity; RNA binding,PF00270;PF00271;,2.00E-160,CHOYP_LOC100368346.1.2,,,,,,,RH42_ORYSJ,Oryza sativa subsp. japonica (Rice),"mRNA splicing, via spliceosome [GO:0000398]; regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]" comp144256_c0_seq2,4844,43.8068,0.54036845,97,83,,0,Q569Z5,Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46),Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46),GO:0005524; GO:0008026; GO:0015030; GO:0003723; GO:0008380; GO:0006397; GO:0016607; GO:0005730,ATP binding; ATP-dependent helicase activity; Cajal body; RNA binding; RNA splicing; mRNA processing; nuclear speck; nucleolus,PF00270;PF00271;,0,CHOYP_DDX46.1.1,,,,,,,DDX46_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]" comp144259_c1_seq1,4848,43.7294,0.63986094,434,504,,0,Q9HCD6,"Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)","Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)",GO:0001701,in utero embryonic development,PF00023;PF12796;PF13181;,0,CHOYP_LOC658414.2.3,,,,,,,TANC2_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701] comp144260_c0_seq1,3360,39.2857,0.62205449,273,1513,,0,Q04678,FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (T160),FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (T160),GO:0003677; GO:0006281; GO:0006260; GO:0005694; GO:0005730; GO:0006355; GO:0006351,"DNA binding; DNA repair; DNA replication; chromosome; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00505;PF08512;PF03531;,0,CHOYP_SSRP1.1.1,,,,,,,SSRP1_CHICK,Gallus gallus (Chicken),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144260_c0_seq2,3084,39.786,0.60883825,52,362,,0,Q9W602,FACT complex subunit SSRP1 (DNA unwinding factor 87 kDa subunit) (DUF87) (Facilitates chromatin transcription complex subunit ssrp1) (Structure-specific recognition protein 1),FACT complex subunit SSRP1 (DNA unwinding factor 87 kDa subunit) (DUF87) (Facilitates chromatin transcription complex subunit ssrp1) (Structure-specific recognition protein 1),GO:0003677; GO:0006281; GO:0006260; GO:0005694; GO:0005730; GO:0006355; GO:0006351,"DNA binding; DNA repair; DNA replication; chromosome; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00505;PF08512;PF03531;,0,CHOYP_SSRP1.1.1,,,,,,,SSRP1_XENLA,Xenopus laevis (African clawed frog),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144261_c0_seq1,3358,36.2716,0.47365671,150,736,,5.00E-08,Q9C5D2,F-box/LRR-repeat protein 4 (AtFBL4),F-box/LRR-repeat protein 4 (AtFBL4),,,PF12937;PF13516;,,,,,,,,,FBL4_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp144262_c1_seq1,1250,47.68,0.55491001,27,70,,0,B7ZC77,Catenin alpha-2 (Alpha N-catenin),Catenin alpha-2 (Alpha N-catenin),GO:0015629; GO:0005912; GO:0030424; GO:0007409; GO:0048854; GO:0016337; GO:0005737; GO:0048813; GO:0005886; GO:0051823; GO:0005198,actin cytoskeleton; adherens junction; axon; axonogenesis; brain morphogenesis; cell-cell adhesion; cytoplasm; dendrite morphogenesis; plasma membrane; regulation of synapse structural plasticity; structural molecule activity,PF01044;,0,CHOYP_PHUM_PHUM450820.1.1,,,,,,,CTNA2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337] comp144262_c1_seq3,4815,39.5846,0.52852844,13,25,,0,Q5R416,Catenin alpha-2 (Alpha N-catenin),Catenin alpha-2 (Alpha N-catenin),GO:0015629; GO:0005912; GO:0030424; GO:0007409; GO:0016323; GO:0048854; GO:0005913; GO:0016337; GO:0005737; GO:0048813; GO:0030027; GO:0060134; GO:0021942; GO:0051823; GO:0005198,actin cytoskeleton; adherens junction; axon; axonogenesis; basolateral plasma membrane; brain morphogenesis; cell-cell adherens junction; cell-cell adhesion; cytoplasm; dendrite morphogenesis; lamellipodium; prepulse inhibition; radial glia guided migration of Purkinje cell; regulation of synapse structural plasticity; structural molecule activity,PF01044;,0,CHOYP_PHUM_PHUM450820.1.1,,,,,,,CTNA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337] comp144262_c1_seq8,4863,39.4612,0.5216086,35,103,,0,Q5R416,Catenin alpha-2 (Alpha N-catenin),Catenin alpha-2 (Alpha N-catenin),GO:0015629; GO:0005912; GO:0030424; GO:0007409; GO:0016323; GO:0048854; GO:0005913; GO:0016337; GO:0005737; GO:0048813; GO:0030027; GO:0060134; GO:0021942; GO:0051823; GO:0005198,actin cytoskeleton; adherens junction; axon; axonogenesis; basolateral plasma membrane; brain morphogenesis; cell-cell adherens junction; cell-cell adhesion; cytoplasm; dendrite morphogenesis; lamellipodium; prepulse inhibition; radial glia guided migration of Purkinje cell; regulation of synapse structural plasticity; structural molecule activity,PF01044;,0,CHOYP_PHUM_PHUM450820.1.1,,,2.00E-117,AM863520.p.cg.6,3,,CTNA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337] comp144264_c0_seq2,4985,35.0251,0.4393934,129,1378,,0,P31401,V-type proton ATPase subunit B (V-ATPase subunit B) (Vacuolar proton pump subunit B),V-type proton ATPase subunit B (V-ATPase subunit B) (Vacuolar proton pump subunit B),GO:0005524; GO:0015991; GO:0046034; GO:0016820; GO:0033180,"ATP binding; ATP hydrolysis coupled proton transport; ATP metabolic process; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; proton-transporting V-type ATPase, V1 domain",PF00006;PF02874;,0,CHOYP_VATB.2.2,,,,,,,VATB_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),ATP hydrolysis coupled proton transport [GO:0015991]; ATP metabolic process [GO:0046034] comp144265_c0_seq1,2193,41.4957,0.50225699,283,323,,0,O54874,Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0004674; GO:0051056; GO:0005083,ATP binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; protein serine/threonine kinase activity; regulation of small GTPase mediated signal transduction; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;,0,CHOYP_GEK.1.1,,,,,,,MRCKA_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056] comp144265_c0_seq5,2419,41.8768,0.67743211,169,214,,1.00E-07,Q01583,Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),GO:0005524; GO:0003951; GO:0005509; GO:0004143; GO:0035556; GO:0007205,ATP binding; NAD+ kinase activity; calcium ion binding; diacylglycerol kinase activity; intracellular signal transduction; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF14513;PF00609;PF00781;,1.00E-120,CHOYP_CDC42BPA.1.1,,,,,,,DGK1_DROME,Drosophila melanogaster (Fruit fly),intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313] comp144265_c1_seq10,2147,39.5901,0.46904825,0,0,,3.00E-68,Q5VT25,Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0000226; GO:0007097; GO:0005543; GO:0004674; GO:0005083,ATP binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; microtubule cytoskeleton organization; nuclear migration; phospholipid binding; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;,2.00E-53,CHOYP_CDC42BPA.1.1,,,,,,,MRCKA_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp144265_c1_seq17,1299,45.4196,0.47895395,0,0,,,,,,,,,1.00E-53,CHOYP_CDC42BPA.1.1,,,,,,,,, comp144265_c1_seq18,1218,44.9097,0.44024909,0,0,,5.00E-71,Q5VT25,Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0000226; GO:0007097; GO:0005543; GO:0004674; GO:0005083,ATP binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; microtubule cytoskeleton organization; nuclear migration; phospholipid binding; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;,1.00E-42,CHOYP_SI_CH211-89P3.3.1.1,,,,,,,MRCKA_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp144265_c1_seq2,1309,45.3782,0.47614748,0,0,,4.00E-06,Q9Y7U6,Rho1 guanine nucleotide exchange factor 1,Rho1 guanine nucleotide exchange factor 1,GO:0005089; GO:0051666; GO:0000935; GO:0000917; GO:0051285; GO:0009272; GO:0035556; GO:0005634; GO:0005543; GO:0035025; GO:0051518; GO:0032319; GO:0008360; GO:0090334,Rho guanyl-nucleotide exchange factor activity; actin cortical patch localization; barrier septum; barrier septum assembly; cell cortex of cell tip; fungal-type cell wall biogenesis; intracellular signal transduction; nucleus; phospholipid binding; positive regulation of Rho protein signal transduction; positive regulation of bipolar cell growth; regulation of Rho GTPase activity; regulation of cell shape; regulation of cell wall (1->3)-beta-D-glucan biosynthetic process,PF00780;PF00610;PF00621;,,,,,,,,,RGF1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),actin cortical patch localization [GO:0051666]; barrier septum assembly [GO:0000917]; fungal-type cell wall biogenesis [GO:0009272]; intracellular signal transduction [GO:0035556]; positive regulation of bipolar cell growth [GO:0051518]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cell shape [GO:0008360]; regulation of cell wall (1->3)-beta-D-glucan biosynthetic process [GO:0090334]; regulation of GTPase activity [GO:0043087] comp144265_c1_seq22,559,44.186,0.41215173,0,0,,8.00E-07,Q9UTR5,Rho1 guanine nucleotide exchange factor 2,Rho1 guanine nucleotide exchange factor 2,GO:0005089; GO:0051666; GO:0030476; GO:0000935; GO:0000917; GO:0051285; GO:0005829; GO:0035556; GO:0005543; GO:0032319; GO:0060622,Rho guanyl-nucleotide exchange factor activity; actin cortical patch localization; ascospore wall assembly; barrier septum; barrier septum assembly; cell cortex of cell tip; cytosol; intracellular signal transduction; phospholipid binding; regulation of Rho GTPase activity; regulation of ascospore wall beta-glucan biosynthetic process,PF00780;PF00610;PF00621;,,,,,,,,,RGF2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),actin cortical patch localization [GO:0051666]; ascospore wall assembly [GO:0030476]; barrier septum assembly [GO:0000917]; fungal-type cell wall biogenesis [GO:0009272]; intracellular signal transduction [GO:0035556]; regulation of ascospore wall beta-glucan biosynthetic process [GO:0060622]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023] comp144265_c1_seq23,1228,44.8697,0.43743603,0,0,,2.00E-59,Q7TT49,Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta),Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta),GO:0005524; GO:0017048; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0005886; GO:0004674; GO:0005083,ATP binding; Rho GTPase binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;,,,,,,,,,MRCKB_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp144265_c1_seq4,2157,39.592,0.46677843,0,0,,5.00E-40,Q80UW5,Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0031252; GO:0005813; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0004674; GO:0005083,ATP binding; actin cytoskeleton reorganization; cell leading edge; centrosome; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF00069;PF00433;,,,,,,,,,MRCKG_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp144265_c1_seq6,2066,39.061,0.43561654,0,0,,1.00E-68,Q5VT25,Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha),GO:0005524; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0000226; GO:0007097; GO:0005543; GO:0004674; GO:0005083,ATP binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; microtubule cytoskeleton organization; nuclear migration; phospholipid binding; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;,2.00E-53,CHOYP_CDC42BPA.1.1,,,,,,,MRCKA_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp144265_c1_seq7,2076,39.1618,0.43164519,0,0,,1.00E-57,Q7TT49,Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta),Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta),GO:0005524; GO:0017048; GO:0031532; GO:0042641; GO:0031032; GO:0031252; GO:0016477; GO:0005911; GO:0005737; GO:0035556; GO:0000287; GO:0005543; GO:0005886; GO:0004674; GO:0005083,ATP binding; Rho GTPase binding; actin cytoskeleton reorganization; actomyosin; actomyosin structure organization; cell leading edge; cell migration; cell-cell junction; cytoplasm; intracellular signal transduction; magnesium ion binding; phospholipid binding; plasma membrane; protein serine/threonine kinase activity; small GTPase regulator activity,PF00130;PF00780;PF08826;PF15796;PF00069;,,,,,,,,,MRCKB_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp144267_c0_seq1,1523,43.9921,0.48889266,35,148,,2.00E-158,Q6DIK0,Protein asunder homolog (Cell cycle regulator Mat89Bb homolog),Protein asunder homolog (Cell cycle regulator Mat89Bb homolog),GO:0051301; GO:0005737; GO:0007067; GO:0007275; GO:0005634; GO:0080154; GO:0007346; GO:0030317,cell division; cytoplasm; mitosis; multicellular organismal development; nucleus; regulation of fertilization; regulation of mitotic cell cycle; sperm motility,PF10221;,7.00E-103,CHOYP_ASUN.1.1,,,,,,,ASUN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]; regulation of fertilization [GO:0080154]; regulation of mitotic cell cycle [GO:0007346]; sperm motility [GO:0030317] comp144268_c0_seq1,3482,39.3739,0.99545516,46,879,,3.00E-90,Q8BYF6,Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8),Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8),GO:0016324; GO:0006915; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; apoptotic process; integral to membrane; sodium ion transport; symporter activity,PF00474;,3.00E-42,CHOYP_LOC582008.3.3,,,,,,,SC5A8_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; sodium ion transport [GO:0006814] comp144268_c0_seq2,2579,38.038,0.97465574,0,49,,3.00E-29,Q8N695,Sodium-coupled monocarboxylate transporter 1 (Apical iodide transporter) (Electrogenic sodium monocarboxylate cotransporter) (Sodium iodide-related cotransporter) (Solute carrier family 5 member 8),Sodium-coupled monocarboxylate transporter 1 (Apical iodide transporter) (Electrogenic sodium monocarboxylate cotransporter) (Sodium iodide-related cotransporter) (Solute carrier family 5 member 8),GO:0016324; GO:0006915; GO:0016021; GO:0006811; GO:0005886; GO:0006814; GO:0015293; GO:0055085,apical plasma membrane; apoptotic process; integral to membrane; ion transport; plasma membrane; sodium ion transport; symporter activity; transmembrane transport,PF00474;,1.00E-14,CHOYP_LOC582008.3.3,,,,,,,SC5A8_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; ion transport [GO:0006811]; sodium ion transport [GO:0006814] comp144270_c0_seq2,4132,41.8441,0.33540274,0,0,,9.00E-21,Q66PY1,"Signal peptide, CUB and EGF-like domain-containing protein 3","Signal peptide, CUB and EGF-like domain-containing protein 3",GO:0005509; GO:0009986; GO:0005576; GO:0051291; GO:0051260,calcium ion binding; cell surface; extracellular region; protein heterooligomerization; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB3_MOUSE,Mus musculus (Mouse),protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] comp144270_c0_seq3,4430,41.851,0.35518872,26,0,,5.00E-21,Q66PY1,"Signal peptide, CUB and EGF-like domain-containing protein 3","Signal peptide, CUB and EGF-like domain-containing protein 3",GO:0005509; GO:0009986; GO:0005576; GO:0051291; GO:0051260,calcium ion binding; cell surface; extracellular region; protein heterooligomerization; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB3_MOUSE,Mus musculus (Mouse),protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] comp144270_c0_seq5,4448,41.839,0.34338421,16,3,,1.00E-13,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp144270_c0_seq6,4150,41.8313,0.32859403,0,0,,6.00E-21,Q66PY1,"Signal peptide, CUB and EGF-like domain-containing protein 3","Signal peptide, CUB and EGF-like domain-containing protein 3",GO:0005509; GO:0009986; GO:0005576; GO:0051291; GO:0051260,calcium ion binding; cell surface; extracellular region; protein heterooligomerization; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB3_MOUSE,Mus musculus (Mouse),protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] comp144270_c1_seq1,623,40.4494,0.16171082,186,2,,1.00E-08,Q9NYQ8,Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),GO:0005509; GO:0005913; GO:0010631; GO:0007156; GO:0016021; GO:0005634; GO:0005886,calcium ion binding; cell-cell adherens junction; epithelial cell migration; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT2_HUMAN,Homo sapiens (Human),epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp144270_c1_seq2,559,39.5349,0.44927938,138,16,,2.00E-32,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp144271_c0_seq1,5975,45.3724,0.45046753,1635,85,,1.00E-09,Q9QXL7,Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-R7),Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-R7),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0046872; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; metal ion binding; nucleoside diphosphate kinase activity,PF00334;,2.00E-33,CHOYP_LOC100371374.1.1,,,,,,,NDK7_RAT,Rattus norvegicus (Rat),CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] comp144272_c0_seq1,1618,48.2695,0.31851699,131,504,,3.00E-73,P70581,Nucleoporin p58/p45 (Nucleoporin-like protein 1),Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1),GO:0051028; GO:0031965; GO:0005643; GO:0005487; GO:0015031,mRNA transport; nuclear membrane; nuclear pore; nucleocytoplasmic transporter activity; protein transport,,4.00E-68,CHOYP_LOC100089326.1.1,,,,,,,NUPL1_RAT,Rattus norvegicus (Rat),mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein heterooligomerization [GO:0051291]; protein heterotetramerization [GO:0051290]; protein heterotrimerization [GO:0070208]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of protein import into nucleus [GO:0042306] comp144272_c0_seq2,2057,37.1415,0.3965892,381,2048,,2.00E-63,C3YEM5,"Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt)","Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt)",GO:0005739; GO:0003746,mitochondrion; translation elongation factor activity,PF00889;,1.00E-24,CHOYP_EFTS.2.2,,,,,,,EFTS_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),mitochondrial translational elongation [GO:0070125] comp144273_c1_seq1,2275,43.1648,0.44894919,22,120,,2.00E-60,Q8CE46,Pseudouridylate synthase 7 homolog-like protein (EC 5.4.99.-),Pseudouridylate synthase 7 homolog-like protein (EC 5.4.99.-),GO:0003723; GO:0009982; GO:0001522; GO:0008033,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; tRNA processing,PF01142;,,,,,,,,,PUS7L_MOUSE,Mus musculus (Mouse),pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033] comp144273_c1_seq2,2242,43.3988,0.4506597,23,81,,4.00E-174,Q08DI8,Pseudouridylate synthase 7 homolog (EC 5.4.99.-),Pseudouridylate synthase 7 homolog (EC 5.4.99.-),GO:0003723; GO:0009982; GO:0001522; GO:0008033,RNA binding; pseudouridine synthase activity; pseudouridine synthesis; tRNA processing,PF01142;,,,,,,,,,PUS7_BOVIN,Bos taurus (Bovine),pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033] comp144275_c0_seq1,4050,44.0494,0.53130741,671,1684,,0,Q5ZI08,Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit),Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit),GO:0032044; GO:0032784; GO:0006357; GO:0006351,"DSIF complex; regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF00467;PF03439;PF11942;,0,CHOYP_SPT5H.1.1,5.00E-25,ruditapes_c26035,,,,,SPT5H_CHICK,Gallus gallus (Chicken),"regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144277_c2_seq1,3822,45.7614,0.5508516,829,2210,,4.00E-122,Q96KR1,Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog),Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog),GO:0003677; GO:0003723; GO:0005694; GO:0005737; GO:0007275; GO:0005634; GO:0008270,DNA binding; RNA binding; chromosome; cytoplasm; multicellular organismal development; nucleus; zinc ion binding,PF07528;,0,CHOYP_LOC100371229.1.2,,,,,,,ZFR_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp144277_c2_seq2,1718,39.057,0.5575137,145,421,,,,,,,,,2.00E-84,CHOYP_ZFR.1.1,,,,,,,,, comp144278_c0_seq2,1877,26.6383,0.81316977,308,966,,1.00E-52,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,5.00E-17,CHOYP_POL2.2.2,2.00E-32,ruditapes_c19911,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp144278_c0_seq4,549,27.3224,1.0185219,91,118,,7.00E-07,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp144280_c1_seq1,1087,46.9181,0.78699894,79,450,,1.00E-89,A8XFG2,"Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3)","Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3)",GO:0051539; GO:0008137; GO:0046872; GO:0005739; GO:0048038; GO:0070469,"4 iron, 4 sulfur cluster binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; mitochondrion; quinone binding; respiratory chain",PF01058;,4.00E-66,CHOYP_LOC100875987.2.2,6.00E-74,ruditapes2_c270,,,,,NDUS7_CAEBR,Caenorhabditis briggsae, comp144280_c2_seq1,1126,45.6483,0.4155608,222,815,,1.00E-97,Q5XJS5,THO complex subunit 6 homolog (WD repeat-containing protein 58),THO complex subunit 6 homolog (WD repeat-containing protein 58),GO:0003723; GO:0008380; GO:0006915; GO:0006397; GO:0051028; GO:0007275; GO:0005634,RNA binding; RNA splicing; apoptotic process; mRNA processing; mRNA transport; multicellular organismal development; nucleus,PF00400;,1.00E-21,CHOYP_LOC100373136.1.1,,,,,,,THOC6_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; multicellular organism development [GO:0007275]; RNA splicing [GO:0008380] comp144281_c0_seq1,1073,34.8555,0.46116892,542,86,,5.00E-21,Q96CC6,Inactive rhomboid protein 1 (iRhom1) (Epidermal growth factor receptor-related protein) (Rhomboid 5 homolog 1) (Rhomboid family member 1) (p100hRho),Inactive rhomboid protein 1 (iRhom1) (Epidermal growth factor receptor-related protein) (Rhomboid 5 homolog 1) (Rhomboid family member 1) (p100hRho),GO:0000139; GO:0016477; GO:0008283; GO:0005789; GO:0016021; GO:0050709; GO:0015031; GO:0006508; GO:0042058; GO:0061136,Golgi membrane; cell migration; cell proliferation; endoplasmic reticulum membrane; integral to membrane; negative regulation of protein secretion; protein transport; proteolysis; regulation of epidermal growth factor receptor signaling pathway; regulation of proteasomal protein catabolic process,PF01694;PF12595;,,,,,,,,,RHDF1_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] comp144281_c0_seq6,1177,44.1801,0.28703724,4,0,,5.00E-33,Q6GMF8,Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1),Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1),GO:0000139; GO:0016477; GO:0008283; GO:0005789; GO:0016021; GO:0050709; GO:0015031; GO:0006508; GO:0042058; GO:0061136; GO:0004252,Golgi membrane; cell migration; cell proliferation; endoplasmic reticulum membrane; integral to membrane; negative regulation of protein secretion; protein transport; proteolysis; regulation of epidermal growth factor receptor signaling pathway; regulation of proteasomal protein catabolic process; serine-type endopeptidase activity,PF01694;PF12595;,,,,,,,,,RHDF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] comp144283_c0_seq1,4529,49.8123,0.30314934,1228,229,,9.00E-10,Q04164,Putative epidermal cell surface receptor (Stranded at second protein),Putative epidermal cell surface receptor (Stranded at second protein),GO:0016324; GO:0002168; GO:0005887; GO:0004872,apical plasma membrane; instar larval development; integral to plasma membrane; receptor activity,PF00041;,5.00E-22,CHOYP_KCP.1.13,,,,,,,SAS_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; instar larval development [GO:0002168] comp144283_c0_seq2,1653,44.4041,0.34497361,79,8,,,,,,,,,2.00E-14,CHOYP_KCP.1.13,8.00E-151,ruditapes2_c138,,,,,,, comp144283_c0_seq3,1592,46.7337,0.37992181,0,0,,,,,,,,,1.00E-30,CHOYP_LOC100929680.1.2,,,,,,,,, comp144283_c0_seq4,4956,48.9306,0.30113295,5,0,,,,,,,,,8.00E-51,CHOYP_MATN1.3.5,,,,,,,,, comp144283_c0_seq5,3913,48.5305,0.2875878,27,0,,,,,,,,,5.00E-27,CHOYP_CO6A4.1.1,,,,,,,,, comp144283_c0_seq6,1658,44.2702,0.37073191,29,5,,,,,,,,,2.00E-15,CHOYP_LOC100929680.2.2,9.00E-68,ruditapes_c37487,,,,,,, comp144283_c0_seq7,2092,46.9407,0.36463877,0,0,,,,,,,,,4.00E-51,CHOYP_MATN1.3.5,,,,,,,,, comp144283_c0_seq8,1252,49.9201,0.32345855,3,0,,,,,,,,,2.00E-13,CHOYP_RGD1561408.2.2,,,,,,,,, comp144284_c0_seq1,3978,46.2544,0.5122987,218,224,,0,Q92614,Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain),Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain),GO:0043531; GO:0005524; GO:0003677; GO:0006259; GO:0007030; GO:0048194; GO:0051015; GO:0042641; GO:0031032; GO:0016477; GO:0005793; GO:0003774; GO:0016459; GO:0043066; GO:0050714; GO:0005802,ADP binding; ATP binding; DNA binding; DNA metabolic process; Golgi organization; Golgi vesicle budding; actin filament binding; actomyosin; actomyosin structure organization; cell migration; endoplasmic reticulum-Golgi intermediate compartment; motor activity; myosin complex; negative regulation of apoptotic process; positive regulation of protein secretion; trans-Golgi network,PF00063;PF01576;PF00595;,0,CHOYP_MYO18.1.1,,,,,,,MY18A_HUMAN,Homo sapiens (Human),actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; DNA metabolic process [GO:0006259]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714] comp144284_c0_seq2,3222,46.8963,0.51266331,40,13,,0,Q8IUG5,Unconventional myosin-XVIIIb,Unconventional myosin-XVIIIb,GO:0005524; GO:0005737; GO:0003774; GO:0005634; GO:0030017; GO:0016461,ATP binding; cytoplasm; motor activity; nucleus; sarcomere; unconventional myosin complex,PF00063;,,,,,,,,,MY18B_HUMAN,Homo sapiens (Human), comp144284_c0_seq3,2359,41.5854,0.50335293,0,0,,1.00E-39,Q8IUG5,Unconventional myosin-XVIIIb,Unconventional myosin-XVIIIb,GO:0005524; GO:0005737; GO:0003774; GO:0005634; GO:0030017; GO:0016461,ATP binding; cytoplasm; motor activity; nucleus; sarcomere; unconventional myosin complex,PF00063;,1.00E-88,CHOYP_MYO18.1.1,,,,,,,MY18B_HUMAN,Homo sapiens (Human), comp144284_c0_seq5,2370,41.4346,0.50447462,0,0,,7.00E-78,Q9JMH9,Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain),Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain),GO:0043531; GO:0005524; GO:0007030; GO:0048194; GO:0042641; GO:0031032; GO:0016477; GO:0005856; GO:0005793; GO:0003774; GO:0016459; GO:0050714; GO:0005802,ADP binding; ATP binding; Golgi organization; Golgi vesicle budding; actomyosin; actomyosin structure organization; cell migration; cytoskeleton; endoplasmic reticulum-Golgi intermediate compartment; motor activity; myosin complex; positive regulation of protein secretion; trans-Golgi network,PF00063;PF01576;PF00595;,,,,,,,,,MY18A_MOUSE,Mus musculus (Mouse),actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714] comp144285_c0_seq1,2392,38.8378,0.57064648,486,2013,,3.00E-178,Q6PE01,U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57),U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57),GO:0008380; GO:0071013; GO:0005737; GO:0006397,RNA splicing; catalytic step 2 spliceosome; cytoplasm; mRNA processing,PF00400;,,,,,,,,,SNR40_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144285_c0_seq2,1207,44.2419,0.64915972,16,231,,0,Q6PE01,U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57),U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57),GO:0008380; GO:0071013; GO:0005737; GO:0006397,RNA splicing; catalytic step 2 spliceosome; cytoplasm; mRNA processing,PF00400;,2.00E-145,CHOYP_LOC100373287.1.1,,,,,,,SNR40_MOUSE,Mus musculus (Mouse),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144286_c0_seq1,3456,38.1655,0.37491119,41,97,,0,P30260,Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC),Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC),GO:0005680; GO:0031145; GO:0008283; GO:0005813; GO:0005829; GO:0007091; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979; GO:0005876,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell proliferation; centrosome; cytosol; metaphase/anaphase transition of mitotic cell cycle; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; spindle microtubule,PF00515;PF13181;,7.00E-158,CHOYP_CDC27.1.1,,,,,,,CDC27_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell proliferation [GO:0008283]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp144286_c0_seq2,3441,38.3028,0.37375274,0,89,,3.00E-92,Q8LGU6,Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT),Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT),GO:0005680; GO:0030154; GO:0051301; GO:0009504; GO:0007276; GO:0007067; GO:0016567; GO:0051302; GO:0007346; GO:0051510; GO:0009733; GO:0048829; GO:0010071; GO:0005819,anaphase-promoting complex; cell differentiation; cell division; cell plate; gamete generation; mitosis; protein ubiquitination; regulation of cell division; regulation of mitotic cell cycle; regulation of unidimensional cell growth; response to auxin stimulus; root cap development; root meristem specification; spindle,PF00515;PF13181;,,,,,,,,,CD27B_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle [GO:0007346]; response to auxin [GO:0009733]; root cap development [GO:0048829]; root development [GO:0048364]; root meristem specification [GO:0010071] comp144288_c0_seq1,3420,35.4678,0.3096896,790,1429,,0,P36871,Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1),Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1),GO:0015629; GO:0005829; GO:0019388; GO:0006094; GO:0005978; GO:0005980; GO:0006096; GO:0000287; GO:0004614; GO:0044281,actin cytoskeleton; cytosol; galactose catabolic process; gluconeogenesis; glycogen biosynthetic process; glycogen catabolic process; glycolysis; magnesium ion binding; phosphoglucomutase activity; small molecule metabolic process,PF02878;PF02879;PF02880;PF00408;,0,CHOYP_PGM1.1.1,,,,,,,PGM1_HUMAN,Homo sapiens (Human),galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096] comp144289_c0_seq13,1984,47.2278,0.50674703,0,0,,4.00E-67,Q9UPN6,Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8),Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8),GO:0003723; GO:0008380; GO:0006397; GO:0016363; GO:0000166; GO:0005681,RNA binding; RNA splicing; mRNA processing; nuclear matrix; nucleotide binding; spliceosomal complex,PF04818;PF00076;,2.00E-104,CHOYP_PHUM_PHUM600390.1.1,,,,,,,SCAF8_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144289_c0_seq15,1487,48.9576,0.44988682,0,0,,7.00E-10,O60176,Uncharacterized RNA-binding protein C23E6.01c,Uncharacterized RNA-binding protein C23E6.01c,GO:0070935; GO:0071004; GO:0000932; GO:0005829; GO:0003729; GO:0000166,3'-UTR-mediated mRNA stabilization; U2-type prespliceosome; cytoplasmic mRNA processing body; cytosol; mRNA binding; nucleotide binding,PF00076;,,,,,,,,,YG41_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mRNA catabolic process [GO:0006402] comp144289_c0_seq3,3502,47.5157,0.4207662,0,0,,1.00E-64,Q9UPN6,Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8),Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8),GO:0003723; GO:0008380; GO:0006397; GO:0016363; GO:0000166; GO:0005681,RNA binding; RNA splicing; mRNA processing; nuclear matrix; nucleotide binding; spliceosomal complex,PF04818;PF00076;,4.00E-104,CHOYP_PHUM_PHUM600390.1.1,,,,,,,SCAF8_HUMAN,Homo sapiens (Human),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144289_c0_seq6,3116,48.0103,0.40816071,0,0,,6.00E-36,Q63627,"Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) (Fragment)","Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) (Fragment)",GO:0003723; GO:0006397; GO:0000166,RNA binding; mRNA processing; nucleotide binding,PF00076;,,,,,,,,,SFR15_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397] comp144289_c0_seq8,3613,47.1907,0.44368029,0,0,,9.00E-36,Q63627,"Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) (Fragment)","Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) (Fragment)",GO:0003723; GO:0006397; GO:0000166,RNA binding; mRNA processing; nucleotide binding,PF00076;,4.00E-104,CHOYP_PHUM_PHUM600390.1.1,,,,,,,SFR15_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397] comp144290_c0_seq1,1628,37.1622,0.92997861,0,0,,1.00E-38,Q5RGJ8,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0030154; GO:0016021; GO:0005634,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; cell differentiation; integral to membrane; nucleus,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,,,,,,,,,GNPTA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256] comp144290_c0_seq4,1617,37.1058,0.95797436,0,0,,6.00E-09,Q5KA65,3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase (EC 2.7.8.32) (Xylosylphosphotransferase 1),3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase (EC 2.7.8.32) (Xylosylphosphotransferase 1),GO:0042732; GO:0000139; GO:0016021; GO:0016757,"D-xylose metabolic process; Golgi membrane; integral to membrane; transferase activity, transferring glycosyl groups",PF11380;PF17102;PF17103;,,,,,,,,,XPT1_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),D-xylose metabolic process [GO:0042732] comp144290_c0_seq5,2544,37.3821,0.88184352,1,739,female>male,7.00E-54,Q5RGJ8,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0030154; GO:0016021; GO:0005634,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; cell differentiation; integral to membrane; nucleus,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,4.00E-20,CHOYP_GNPTA.1.3,,,,,,,GNPTA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256] comp144290_c0_seq6,1975,37.8734,0.87918672,0,18,,3.00E-28,O69853,Exopolysaccharide phosphotransferase SCO6023 (EC 2.7.-.-) (Stealth protein SCO6023),Exopolysaccharide phosphotransferase SCO6023 (EC 2.7.-.-) (Stealth protein SCO6023),GO:0000271; GO:0016772,"polysaccharide biosynthetic process; transferase activity, transferring phosphorus-containing groups",PF17101;PF11380;PF17102;PF17103;,3.00E-20,CHOYP_GNPTA.1.3,,,,,,,Y6023_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),polysaccharide biosynthetic process [GO:0000271] comp144291_c1_seq1,651,42.2427,0.20770995,76,796,,2.00E-85,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp144295_c0_seq1,2358,38.2103,0.59985771,60,78,,7.00E-93,Q863A5,Dyslexia susceptibility 1 candidate gene 1 protein homolog,Dyslexia susceptibility 1 candidate gene 1 protein homolog,GO:0005737; GO:0030331; GO:0001764; GO:0005634; GO:0033146; GO:0061136,cytoplasm; estrogen receptor binding; neuron migration; nucleus; regulation of intracellular estrogen receptor signaling pathway; regulation of proteasomal protein catabolic process,PF04969;,1.00E-58,CHOYP_DYXC1.1.1,3.00E-32,ruditapes_c20530,,,,,DYXC1_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),neuron migration [GO:0001764]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136] comp144295_c0_seq2,2376,38.2155,0.61792124,75,100,,8.00E-93,Q863A5,Dyslexia susceptibility 1 candidate gene 1 protein homolog,Dyslexia susceptibility 1 candidate gene 1 protein homolog,GO:0005737; GO:0030331; GO:0001764; GO:0005634; GO:0033146; GO:0061136,cytoplasm; estrogen receptor binding; neuron migration; nucleus; regulation of intracellular estrogen receptor signaling pathway; regulation of proteasomal protein catabolic process,PF04969;,,,,,,,,,DYXC1_GORGO,Gorilla gorilla gorilla (Western lowland gorilla),neuron migration [GO:0001764]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136] comp144295_c0_seq3,2076,39.3064,0.58110919,1,17,,4.00E-13,O70593,Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 1),Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 1),GO:0005737,cytoplasm,PF16546;PF00515;PF13181;,4.00E-57,CHOYP_DYXC1.1.1,,,,,,,SGTA_RAT,Rattus norvegicus (Rat),positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071] comp144296_c0_seq1,3398,46.6745,0.55871037,664,356,,0,O75643,U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD),U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD),GO:0005524; GO:0004004; GO:0005682; GO:0071013; GO:0000354; GO:0003676; GO:0005654,ATP binding; ATP-dependent RNA helicase activity; U5 snRNP; catalytic step 2 spliceosome; cis assembly of pre-catalytic spliceosome; nucleic acid binding; nucleoplasm,PF00270;PF00271;PF02889;,0,CHOYP_U520.1.1,1.00E-101,ruditapes_c10984,,,,,U520_HUMAN,Homo sapiens (Human),"cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]" comp144298_c0_seq1,3534,42.5863,0.41950463,24,186,,1.00E-80,A9VS13,DNA mismatch repair protein MutS,DNA mismatch repair protein MutS,GO:0005524; GO:0003684; GO:0006298; GO:0030983,ATP binding; damaged DNA binding; mismatch repair; mismatched DNA binding,PF01624;PF05188;PF05192;PF05190;PF00488;,0,CHOYP_MSH2.1.1,5.00E-18,ruditapes_c17630,,,,,MUTS_BACWK,Bacillus weihenstephanensis (strain KBAB4),mismatch repair [GO:0006298] comp144298_c0_seq2,3544,42.579,0.41842377,12,60,,0,O13396,DNA mismatch repair protein msh-2,DNA mismatch repair protein msh-2,GO:0005524; GO:0008094; GO:0032301; GO:0032302; GO:0000403; GO:0030466; GO:0003684; GO:0000406; GO:0000400; GO:0032137; GO:0000404; GO:0043570; GO:0006311; GO:0000710; GO:0045128; GO:0000228; GO:0006301; GO:0000735; GO:0032138,ATP binding; DNA-dependent ATPase activity; MutSalpha complex; MutSbeta complex; Y-form DNA binding; chromatin silencing at silent mating-type cassette; damaged DNA binding; double-strand/single-strand DNA junction binding; four-way junction DNA binding; guanine/thymine mispair binding; loop DNA binding; maintenance of DNA repeat elements; meiotic gene conversion; meiotic mismatch repair; negative regulation of reciprocal meiotic recombination; nuclear chromosome; postreplication repair; removal of nonhomologous ends; single base insertion or deletion binding,PF01624;PF05188;PF05192;PF05190;PF00488;,0,CHOYP_MSH2.1.1,,,,,,,MSH2_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),maintenance of DNA repeat elements [GO:0043570]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; negative regulation of reciprocal meiotic recombination [GO:0045128]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; removal of nonhomologous ends [GO:0000735] comp144298_c0_seq3,3547,42.4866,0.41369788,0,47,,0,P43247,DNA mismatch repair protein Msh2 (MutS protein homolog 2),DNA mismatch repair protein Msh2 (MutS protein homolog 2),GO:0043531; GO:0005524; GO:0030183; GO:0008094; GO:0032301; GO:0032302; GO:0000403; GO:0007050; GO:0019237; GO:0003684; GO:0008340; GO:0032181; GO:0006302; GO:0000406; GO:0000400; GO:0007281; GO:0032137; GO:0001701; GO:0031573; GO:0042771; GO:0045190; GO:0000404; GO:0000287; GO:0043570; GO:0008584; GO:0006311; GO:0000710; GO:0043524; GO:0045128; GO:0000228; GO:0006119; GO:0032357; GO:0051096; GO:0006301; GO:0010224; GO:0010165; GO:0032138; GO:0032142; GO:0032143; GO:0003697; GO:0016446,ADP binding; ATP binding; B cell differentiation; DNA-dependent ATPase activity; MutSalpha complex; MutSbeta complex; Y-form DNA binding; cell cycle arrest; centromeric DNA binding; damaged DNA binding; determination of adult lifespan; dinucleotide repeat insertion binding; double-strand break repair; double-strand/single-strand DNA junction binding; four-way junction DNA binding; germ cell development; guanine/thymine mispair binding; in utero embryonic development; intra-S DNA damage checkpoint; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; isotype switching; loop DNA binding; magnesium ion binding; maintenance of DNA repeat elements; male gonad development; meiotic gene conversion; meiotic mismatch repair; negative regulation of neuron apoptotic process; negative regulation of reciprocal meiotic recombination; nuclear chromosome; oxidative phosphorylation; oxidized purine DNA binding; positive regulation of helicase activity; postreplication repair; response to UV-B; response to X-ray; single base insertion or deletion binding; single guanine insertion binding; single thymine insertion binding; single-stranded DNA binding; somatic hypermutation of immunoglobulin genes,PF01624;PF05188;PF05192;PF05190;PF00488;,,,,,,,,,MSH2_MOUSE,Mus musculus (Mouse),B cell differentiation [GO:0030183]; B cell mediated immunity [GO:0019724]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; germ cell development [GO:0007281]; intra-S DNA damage checkpoint [GO:0031573]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; in utero embryonic development [GO:0001701]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; male gonad development [GO:0008584]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of reciprocal meiotic recombination [GO:0045128]; oxidative phosphorylation [GO:0006119]; positive regulation of helicase activity [GO:0051096]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204] comp144298_c0_seq4,1194,37.2697,0.32568157,24,180,,5.00E-36,P54275,DNA mismatch repair protein Msh2 (MutS protein homolog 2),DNA mismatch repair protein Msh2 (MutS protein homolog 2),GO:0005524; GO:0008094; GO:0032301; GO:0032302; GO:0000403; GO:0003684; GO:0006302; GO:0000406; GO:0000400; GO:0032137; GO:0031573; GO:0042771; GO:0045190; GO:0000404; GO:0043570; GO:0006311; GO:0000710; GO:0045128; GO:0000228; GO:0006301; GO:0010224; GO:0010165; GO:0043200; GO:0042493; GO:0014070; GO:0032138; GO:0016446; GO:0007283,ATP binding; DNA-dependent ATPase activity; MutSalpha complex; MutSbeta complex; Y-form DNA binding; damaged DNA binding; double-strand break repair; double-strand/single-strand DNA junction binding; four-way junction DNA binding; guanine/thymine mispair binding; intra-S DNA damage checkpoint; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; isotype switching; loop DNA binding; maintenance of DNA repeat elements; meiotic gene conversion; meiotic mismatch repair; negative regulation of reciprocal meiotic recombination; nuclear chromosome; postreplication repair; response to UV-B; response to X-ray; response to amino acid stimulus; response to drug; response to organic cyclic compound; single base insertion or deletion binding; somatic hypermutation of immunoglobulin genes; spermatogenesis,PF01624;PF05188;PF05192;PF05190;PF00488;,,,,,,,,,MSH2_RAT,Rattus norvegicus (Rat),double-strand break repair [GO:0006302]; intra-S DNA damage checkpoint [GO:0031573]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; negative regulation of reciprocal meiotic recombination [GO:0045128]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283] comp144299_c1_seq1,2534,35.438,0.53805345,1304,1751,,0,Q9VWH4,"Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)","Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)",GO:0051287; GO:0004449; GO:0005811; GO:0000287; GO:0005875; GO:0005739; GO:0006099,NAD binding; isocitrate dehydrogenase (NAD+) activity; lipid particle; magnesium ion binding; microtubule associated complex; mitochondrion; tricarboxylic acid cycle,PF00180;,1.00E-147,CHOYP_LOC587700.1.1,,,,,,,IDH3A_DROME,Drosophila melanogaster (Fruit fly),tricarboxylic acid cycle [GO:0006099] comp144300_c0_seq13,3569,37.9938,0.63738346,20,237,,7.00E-149,Q3UDE2,Tubulin--tyrosine ligase-like protein 12,Tubulin--tyrosine ligase-like protein 12,GO:0006464,cellular protein modification process,PF03133;,6.00E-32,CHOYP_TTL12.1.1,,,,,,,TTL12_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464] comp144300_c0_seq22,2300,35.3913,0.61122929,0,24,,3.00E-46,Q3UDE2,Tubulin--tyrosine ligase-like protein 12,Tubulin--tyrosine ligase-like protein 12,GO:0006464,cellular protein modification process,PF03133;,,,,,,,,,TTL12_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464] comp144300_c0_seq3,3533,38.0696,0.63365583,15,226,,6.00E-149,Q3UDE2,Tubulin--tyrosine ligase-like protein 12,Tubulin--tyrosine ligase-like protein 12,GO:0006464,cellular protein modification process,PF03133;,5.00E-33,CHOYP_TTL12.1.1,,,,,,,TTL12_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464] comp144301_c0_seq1,4159,28.9974,0.54931243,1355,6234,,2.00E-63,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp144301_c0_seq2,2461,30.3129,0.54863322,22,91,,3.00E-65,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,6.00E-43,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp144304_c0_seq1,2700,34.4074,0.57090727,459,3650,,5.00E-42,Q7ZZ00,Zinc finger protein 511,Zinc finger protein 511,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,1.00E-25,CHOYP_LOC100691787.1.1,,,,,,,ZN511_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144305_c1_seq1,7247,40.3201,0.52624131,8,24,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq11,7265,40.3716,0.52711811,0,0,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq13,7608,39.6293,0.52933793,0,0,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq15,7217,40.3215,0.52144529,0,0,,0,Q7PLI2,Nipped-B protein (SCC2 homolog),Nipped-B protein (SCC2 homolog),GO:0032116; GO:0034088; GO:0005654; GO:0005700; GO:0070193; GO:0006351; GO:0071733; GO:0035327,"SMC loading complex; maintenance of mitotic sister chromatid cohesion; nucleoplasm; polytene chromosome; synaptonemal complex organization; transcription, DNA-dependent; transcriptional activation by promoter-enhancer looping; transcriptionally active chromatin",PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPB_DROME,Drosophila melanogaster (Fruit fly),"maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; synaptonemal complex organization [GO:0070193]; transcription, DNA-templated [GO:0006351]; transcriptional activation by promoter-enhancer looping [GO:0071733]" comp144305_c1_seq16,7596,39.6524,0.52627929,0,0,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq2,7626,39.6669,0.53059869,0,0,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,,,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq3,7578,39.6147,0.52499638,0,0,,0,Q7PLI2,Nipped-B protein (SCC2 homolog),Nipped-B protein (SCC2 homolog),GO:0032116; GO:0034088; GO:0005654; GO:0005700; GO:0070193; GO:0006351; GO:0071733; GO:0035327,"SMC loading complex; maintenance of mitotic sister chromatid cohesion; nucleoplasm; polytene chromosome; synaptonemal complex organization; transcription, DNA-dependent; transcriptional activation by promoter-enhancer looping; transcriptionally active chromatin",PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPB_DROME,Drosophila melanogaster (Fruit fly),"maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; synaptonemal complex organization [GO:0070193]; transcription, DNA-templated [GO:0006351]; transcriptional activation by promoter-enhancer looping [GO:0071733]" comp144305_c1_seq5,7338,40.4061,0.52786468,0,0,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq6,7320,40.3689,0.52661149,0,0,,0,Q6KC79,Nipped-B-like protein (Delangin) (SCC2 homolog),Nipped-B-like protein (Delangin) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0034088; GO:0001656; GO:0000122; GO:0005654; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; maintenance of mitotic sister chromatid cohesion; metanephros development; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_HUMAN,Homo sapiens (Human),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; metanephros development [GO:0001656]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144305_c1_seq8,6069,41.506,0.50466863,0,0,,0,Q7PLI2,Nipped-B protein (SCC2 homolog),Nipped-B protein (SCC2 homolog),GO:0032116; GO:0034088; GO:0005654; GO:0005700; GO:0070193; GO:0006351; GO:0071733; GO:0035327,"SMC loading complex; maintenance of mitotic sister chromatid cohesion; nucleoplasm; polytene chromosome; synaptonemal complex organization; transcription, DNA-dependent; transcriptional activation by promoter-enhancer looping; transcriptionally active chromatin",PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPB_DROME,Drosophila melanogaster (Fruit fly),"maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; synaptonemal complex organization [GO:0070193]; transcription, DNA-templated [GO:0006351]; transcriptional activation by promoter-enhancer looping [GO:0071733]" comp144305_c1_seq9,7710,39.7147,0.53692764,0,0,,0,Q6KCD5,Nipped-B-like protein (Delangin homolog) (SCC2 homolog),Nipped-B-like protein (Delangin homolog) (SCC2 homolog),GO:0032116; GO:0007420; GO:0034613; GO:0071481; GO:0003682; GO:0050890; GO:0048589; GO:0042471; GO:0048557; GO:0035115; GO:0048703; GO:0035261; GO:0048592; GO:0060325; GO:0045444; GO:0061010; GO:0007507; GO:0034088; GO:0036033; GO:0000122; GO:0003151; GO:0031065; GO:0040018; GO:0045778; GO:0048638; GO:0045995; GO:0042634; GO:0006974; GO:0007605; GO:0019827; GO:0061038,SMC loading complex; brain development; cellular protein localization; cellular response to X-ray; chromatin binding; cognition; developmental growth; ear morphogenesis; embryonic digestive tract morphogenesis; embryonic forelimb morphogenesis; embryonic viscerocranium morphogenesis; external genitalia morphogenesis; eye morphogenesis; face morphogenesis; fat cell differentiation; gall bladder development; heart development; maintenance of mitotic sister chromatid cohesion; mediator complex binding; negative regulation of transcription from RNA polymerase II promoter; outflow tract morphogenesis; positive regulation of histone deacetylation; positive regulation of multicellular organism growth; positive regulation of ossification; regulation of developmental growth; regulation of embryonic development; regulation of hair cycle; response to DNA damage stimulus; sensory perception of sound; stem cell maintenance; uterus morphogenesis,PF12765;PF12830;,0,CHOYP_NIPLB.1.1,,,,,,,NIPBL_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]" comp144307_c0_seq1,1498,32.9773,0.49322212,10,87,,1.00E-07,P08820,Subtilisin inhibitor (Fragment),Subtilisin inhibitor (Fragment),GO:0009611; GO:0004867,response to wounding; serine-type endopeptidase inhibitor activity,PF00280;,,,,,,,,,ICIS_VICFA,Vicia faba (Broad bean) (Faba vulgaris),response to wounding [GO:0009611] comp144307_c0_seq2,1033,34.85,0.67487243,15,130,,9.00E-09,P01054,Subtilisin-chymotrypsin inhibitor CI-1C,Subtilisin-chymotrypsin inhibitor CI-1C,GO:0009611; GO:0004867,response to wounding; serine-type endopeptidase inhibitor activity,PF00280;,,,,,,,,,ICIC_HORVU,Hordeum vulgare (Barley),response to wounding [GO:0009611] comp144307_c0_seq3,1455,33.5395,0.63692069,2,24,,8.00E-12,P82977,Subtilisin-chymotrypsin inhibitor WSCI,Subtilisin-chymotrypsin inhibitor WSCI,GO:0005576; GO:0009611; GO:0004867,extracellular region; response to wounding; serine-type endopeptidase inhibitor activity,PF00280;,,,,,,,,,ICIW_WHEAT,Triticum aestivum (Wheat),response to wounding [GO:0009611] comp144308_c0_seq1,4568,47.3949,0.56306036,1,0,,0,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp144308_c0_seq2,6650,47.7293,0.52833905,5,17,,0,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,6.00E-35,CHOYP_HMCN1.28.44,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp144308_c0_seq3,4401,47.0575,0.55576133,0,0,,1.00E-76,Q6WRH9,Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608),Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608),GO:0030154; GO:0005576; GO:0007275; GO:0001503; GO:0042246,cell differentiation; extracellular region; multicellular organismal development; ossification; tissue regeneration,PF07679;PF13855;,,,,,,,,,IGS10_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; tissue regeneration [GO:0042246] comp144308_c0_seq4,5432,46.8704,0.53487225,10,0,,3.00E-76,Q6WRH9,Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608),Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608),GO:0030154; GO:0005576; GO:0007275; GO:0001503; GO:0042246,cell differentiation; extracellular region; multicellular organismal development; ossification; tissue regeneration,PF07679;PF13855;,,,,,,,,,IGS10_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; tissue regeneration [GO:0042246] comp144308_c0_seq5,6642,47.9223,0.52492941,12,0,,0,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp144308_c0_seq6,2417,47.7038,0.54849842,58,5,,0,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,3.00E-46,CHOYP_HMCN1.28.44,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp144308_c0_seq7,1399,49.035,0.50364483,4,0,,3.00E-15,P35442,Thrombospondin-2,Thrombospondin-2,GO:0005604; GO:0005509; GO:0007155; GO:0005576; GO:0008201; GO:0016525,basement membrane; calcium ion binding; cell adhesion; extracellular region; heparin binding; negative regulation of angiogenesis,PF12947;PF07645;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]; positive regulation of synapse assembly [GO:0051965] comp144308_c0_seq8,831,45.367,0.77271304,3,1,,1.00E-06,P25723,Dorsal-ventral patterning protein tolloid (EC 3.4.24.-),Dorsal-ventral patterning protein tolloid (EC 3.4.24.-),GO:0007378; GO:0005509; GO:0005576; GO:0008586; GO:0007313; GO:0004222; GO:0010629; GO:0030513; GO:0016485; GO:0006508; GO:0017015; GO:0007362; GO:0008293; GO:0008270,"amnioserosa formation; calcium ion binding; extracellular region; imaginal disc-derived wing vein morphogenesis; maternal specification of dorsal/ventral axis, oocyte, soma encoded; metalloendopeptidase activity; negative regulation of gene expression; positive regulation of BMP signaling pathway; protein processing; proteolysis; regulation of transforming growth factor beta receptor signaling pathway; terminal region determination; torso signaling pathway; zinc ion binding",PF01400;PF00431;PF07645;,,,,,,,,,TLD_DROME,Drosophila melanogaster (Fruit fly),"amnioserosa formation [GO:0007378]; embryonic pattern specification [GO:0009880]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; negative regulation of gene expression [GO:0010629]; positive regulation of BMP signaling pathway [GO:0030513]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; zygotic specification of dorsal/ventral axis [GO:0007352]" comp144308_c0_seq9,476,49.1597,0.5925492,0,7,,2.00E-17,O60242,Brain-specific angiogenesis inhibitor 3,Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3),GO:0004930; GO:0016021; GO:0016525; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; negative regulation of angiogenesis; neuropeptide signaling pathway; plasma membrane,PF00002;PF16489;PF01825;PF02793;PF00090;,,,,,,,,,BAI3_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; myoblast fusion [GO:0007520]; negative regulation of angiogenesis [GO:0016525]; positive regulation of synapse assembly [GO:0051965]; regulation of dendrite morphogenesis [GO:0048814] comp144310_c0_seq2,927,29.1262,0.5120006,30,117,,,,,,,,,,,2.00E-17,ruditapes2_c1847,,,,,,, comp144311_c1_seq1,4180,34.8086,0.47609851,1478,6315,,8.00E-166,Q99615,DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2),DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2),GO:0070389; GO:0005737; GO:0005856; GO:0005634,chaperone cofactor-dependent protein refolding; cytoplasm; cytoskeleton; nucleus,PF00226;PF13414;PF13181;,2.00E-127,CHOYP_DNJC7.1.1,,,,,,,DNJC7_HUMAN,Homo sapiens (Human),chaperone cofactor-dependent protein refolding [GO:0070389]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034] comp144312_c0_seq1,2809,43.5742,0.60786133,1092,1237,,3.00E-97,E2RYF8,Targeting protein for Xklp2 homolog (TPX2 homolog) (Microtubule-associated protein TPX2 homolog),Targeting protein for Xklp2 homolog (TPX2 homolog) (Microtubule-associated protein TPX2 homolog),GO:0005737; GO:0005874; GO:0007067; GO:0005634; GO:0005819,cytoplasm; microtubule; mitosis; nucleus; spindle,PF06886;PF12214;,,,,,,,,,TPX2_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),activation of protein kinase activity [GO:0032147]; regulation of mitotic spindle organization [GO:0060236] comp144313_c0_seq1,1940,31.1856,0.59464325,2031,6862,,,,,,,,,,,9.00E-12,ruditapes_c18355,,,,,,, comp144313_c1_seq1,6499,48.2382,0.43354466,1556,4124,,3.00E-129,P17140,Collagen alpha-2(IV) chain (Lethal protein 2),Collagen alpha-2(IV) chain (Lethal protein 2),GO:0016043; GO:0005587; GO:0009792; GO:0030020,cellular component organization; collagen type IV; embryo development ending in birth or egg hatching; extracellular matrix structural constituent conferring tensile strength,PF01413;PF01391;,3.00E-58,CHOYP_CBR-LET-2.2.2,,,,,,,CO4A2_CAEEL,Caenorhabditis elegans,cellular component organization [GO:0016043]; embryo development ending in birth or egg hatching [GO:0009792] comp144314_c0_seq1,7912,37.955,0.3098863,3874,375,,2.00E-32,Q96B97,SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1),SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1),GO:0006915; GO:0016477; GO:0007267; GO:0030659; GO:0005856; GO:0007010; GO:0005829; GO:0006897; GO:0007173; GO:0005925; GO:0042059; GO:0043005; GO:0005886; GO:0008360; GO:0045202,apoptotic process; cell migration; cell-cell signaling; cytoplasmic vesicle membrane; cytoskeleton; cytoskeleton organization; cytosol; endocytosis; epidermal growth factor receptor signaling pathway; focal adhesion; negative regulation of epidermal growth factor receptor signaling pathway; neuron projection; plasma membrane; regulation of cell shape; synapse,PF14604;,7.00E-29,CHOYP_BRAFLDRAFT_90471.2.2,,,,,,,SH3K1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; regulation of cell shape [GO:0008360] comp144314_c1_seq1,251,50.996,0.68092459,4,8,,3.00E-15,Q96B97,SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1),SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1),GO:0006915; GO:0016477; GO:0007267; GO:0030659; GO:0005856; GO:0007010; GO:0005829; GO:0006897; GO:0007173; GO:0005925; GO:0042059; GO:0043005; GO:0005886; GO:0008360; GO:0045202,apoptotic process; cell migration; cell-cell signaling; cytoplasmic vesicle membrane; cytoskeleton; cytoskeleton organization; cytosol; endocytosis; epidermal growth factor receptor signaling pathway; focal adhesion; negative regulation of epidermal growth factor receptor signaling pathway; neuron projection; plasma membrane; regulation of cell shape; synapse,PF14604;,1.00E-21,CHOYP_SH3KBP1.1.1,,,,,,,SH3K1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; regulation of cell shape [GO:0008360] comp144315_c1_seq1,8081,39.7352,0.4000959,145,19714,female>male,1.00E-17,P18948,Vitellogenin-6,Vitellogenin-6,GO:0005576; GO:0005319; GO:0045735,extracellular region; lipid transporter activity; nutrient reservoir activity,PF09172;PF01347;PF00094;,,,,,,,,,VIT6_CAEEL,Caenorhabditis elegans, comp144316_c0_seq1,1219,35.0287,0.52562394,491,1030,,3.00E-73,O60830,Mitochondrial import inner membrane translocase subunit Tim17-B,Mitochondrial import inner membrane translocase subunit Tim17-B,GO:0015450; GO:0044267; GO:0031305; GO:0015630; GO:0005744; GO:0006626,P-P-bond-hydrolysis-driven protein transmembrane transporter activity; cellular protein metabolic process; integral to mitochondrial inner membrane; microtubule cytoskeleton; mitochondrial inner membrane presequence translocase complex; protein targeting to mitochondrion,PF02466;,,,,,,,,,TI17B_HUMAN,Homo sapiens (Human),protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] comp144316_c0_seq2,566,41.5194,0.50400157,83,160,,1.00E-76,O60830,Mitochondrial import inner membrane translocase subunit Tim17-B,Mitochondrial import inner membrane translocase subunit Tim17-B,GO:0015450; GO:0044267; GO:0031305; GO:0015630; GO:0005744; GO:0006626,P-P-bond-hydrolysis-driven protein transmembrane transporter activity; cellular protein metabolic process; integral to mitochondrial inner membrane; microtubule cytoskeleton; mitochondrial inner membrane presequence translocase complex; protein targeting to mitochondrion,PF02466;,,,3.00E-18,ruditapes_c22880,,,,,TI17B_HUMAN,Homo sapiens (Human),protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] comp144316_c1_seq5,3264,35.9988,0.39185815,90,145,,2.00E-09,Q5M9G9,Protein TBRG4 (Transforming growth factor beta regulator 4),Protein TBRG4 (Transforming growth factor beta regulator 4),GO:0045333; GO:0005739; GO:0004672; GO:0006468,cellular respiration; mitochondrion; protein kinase activity; protein phosphorylation,PF06743;PF08368;PF08373;,,,,,,,,,TBRG4_RAT,Rattus norvegicus (Rat),cellular respiration [GO:0045333] comp144318_c0_seq1,7784,41.2384,0.48413399,0,47,,0,Q03001,Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0009925; GO:0005604; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0031252; GO:0048870; GO:0016023; GO:0031122; GO:0005829; GO:0005789; GO:0030198; GO:0030056; GO:0031581; GO:0016021; GO:0007229; GO:0005882; GO:0045111; GO:0045104; GO:0030011; GO:0015630; GO:0000226; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0042803; GO:0031110; GO:0009611; GO:0008090,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; basal plasma membrane; basement membrane; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cell leading edge; cell motility; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; cytosol; endoplasmic reticulum membrane; extracellular matrix organization; hemidesmosome; hemidesmosome assembly; integral to membrane; integrin-mediated signaling pathway; intermediate filament; intermediate filament cytoskeleton; intermediate filament cytoskeleton organization; maintenance of cell polarity; microtubule cytoskeleton; microtubule cytoskeleton organization; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; response to wounding; retrograde axon cargo transport,PF00307;PF13499;PF02187;PF00681;PF00435;,0,CHOYP_LOC100118464.1.1,,,,,,,DYST_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611] comp144318_c0_seq10,694,43.5159,0.67132208,0,0,,,,,,,,,1.00E-45,CHOYP_LOC662585.2.2,,,,,,,,, comp144318_c0_seq11,4786,44.7973,0.36827855,0,0,,,,,,,,,,,5.00E-32,ruditapes_c16373,,,,,,, comp144318_c0_seq12,3213,44.6623,0.32964106,0,0,,2.00E-84,Q91ZU6,Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0016023; GO:0031122; GO:0005789; GO:0005925; GO:0030056; GO:0016021; GO:0014704; GO:0005882; GO:0045104; GO:0009898; GO:0046907; GO:0015630; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0097038; GO:0042803; GO:0031110; GO:0008090; GO:0042383; GO:0001725,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; endoplasmic reticulum membrane; focal adhesion; hemidesmosome; integral to membrane; intercalated disc; intermediate filament; intermediate filament cytoskeleton organization; internal side of plasma membrane; intracellular transport; microtubule cytoskeleton; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; retrograde axon cargo transport; sarcolemma; stress fiber,PF00307;PF13499;PF02187;PF00681;PF00435;,,,,,,,,,DYST_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090] comp144318_c0_seq13,883,45.8664,0.67275581,0,0,,2.00E-17,Q99501,GAS2-like protein 1 (GAS2-related protein on chromosome 22) (Growth arrest-specific protein 2-like 1),GAS2-like protein 1 (GAS2-related protein on chromosome 22) (Growth arrest-specific protein 2-like 1),GO:0007050; GO:0009267; GO:0097067; GO:0005737; GO:0008093; GO:0005874; GO:0008017; GO:0001578; GO:0030308; GO:0045647; GO:0010629; GO:0007026; GO:0051726; GO:0001725; GO:0046966,cell cycle arrest; cellular response to starvation; cellular response to thyroid hormone stimulus; cytoplasm; cytoskeletal adaptor activity; microtubule; microtubule binding; microtubule bundle formation; negative regulation of cell growth; negative regulation of erythrocyte differentiation; negative regulation of gene expression; negative regulation of microtubule depolymerization; regulation of cell cycle; stress fiber; thyroid hormone receptor binding,PF00307;PF02187;,,,,,,,,,GA2L1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of cell cycle [GO:0051726] comp144318_c0_seq14,3794,36.9004,0.57644654,0,0,,4.00E-89,D3ZHV2,Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7),Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7),GO:0016887; GO:0005794; GO:0043001; GO:0016055; GO:0005509; GO:0007050; GO:0005874; GO:0030177; GO:0010632; GO:0051893; GO:0032886; GO:0032587; GO:0042060,ATPase activity; Golgi apparatus; Golgi to plasma membrane protein transport; Wnt receptor signaling pathway; calcium ion binding; cell cycle arrest; microtubule; positive regulation of Wnt receptor signaling pathway; regulation of epithelial cell migration; regulation of focal adhesion assembly; regulation of microtubule-based process; ruffle membrane; wound healing,PF00307;PF13499;PF02187;PF00435;,3.00E-105,CHOYP_LOC662585.2.2,1.00E-39,ruditapes_c21015,,,,,MACF1_RAT,Rattus norvegicus (Rat),cell cycle arrest [GO:0007050]; Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] comp144318_c0_seq2,3818,36.8779,0.57293912,0,0,,9.00E-17,Q8JZP9,GAS2-like protein 1 (Growth arrest-specific protein 2-like 1),GAS2-like protein 1 (Growth arrest-specific protein 2-like 1),GO:0007050; GO:0009267; GO:0097067; GO:0005737; GO:0008093; GO:0005856; GO:0008017; GO:0001578; GO:0030308; GO:0045647; GO:0010629; GO:0007026; GO:0051726; GO:0046966,cell cycle arrest; cellular response to starvation; cellular response to thyroid hormone stimulus; cytoplasm; cytoskeletal adaptor activity; cytoskeleton; microtubule binding; microtubule bundle formation; negative regulation of cell growth; negative regulation of erythrocyte differentiation; negative regulation of gene expression; negative regulation of microtubule depolymerization; regulation of cell cycle; thyroid hormone receptor binding,PF00307;PF02187;,,,,,,,,,GA2L1_MOUSE,Mus musculus (Mouse),cell cycle arrest [GO:0007050]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of cell cycle [GO:0051726] comp144318_c0_seq3,859,46.2165,0.68254061,0,0,,2.00E-16,Q5SSG4,GAS2-like protein 2 (Growth arrest-specific protein 2-like 2),GAS2-like protein 2 (Growth arrest-specific protein 2-like 2),GO:0051015; GO:0007050; GO:0005737; GO:0008093; GO:0005874; GO:0008017; GO:0001578; GO:0007026; GO:0001725,actin filament binding; cell cycle arrest; cytoplasm; cytoskeletal adaptor activity; microtubule; microtubule binding; microtubule bundle formation; negative regulation of microtubule depolymerization; stress fiber,PF00307;PF02187;,8.00E-80,CHOYP_LOC662585.2.2,,,,,,,GA2L2_MOUSE,Mus musculus (Mouse),cell cycle arrest [GO:0007050]; microtubule bundle formation [GO:0001578]; negative regulation of microtubule depolymerization [GO:0007026] comp144318_c0_seq5,4427,45.855,0.45487589,21,0,,0,Q03001,Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0009925; GO:0005604; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0031252; GO:0048870; GO:0016023; GO:0031122; GO:0005829; GO:0005789; GO:0030198; GO:0030056; GO:0031581; GO:0016021; GO:0007229; GO:0005882; GO:0045111; GO:0045104; GO:0030011; GO:0015630; GO:0000226; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0042803; GO:0031110; GO:0009611; GO:0008090,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; basal plasma membrane; basement membrane; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cell leading edge; cell motility; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; cytosol; endoplasmic reticulum membrane; extracellular matrix organization; hemidesmosome; hemidesmosome assembly; integral to membrane; integrin-mediated signaling pathway; intermediate filament; intermediate filament cytoskeleton; intermediate filament cytoskeleton organization; maintenance of cell polarity; microtubule cytoskeleton; microtubule cytoskeleton organization; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; response to wounding; retrograde axon cargo transport,PF00307;PF13499;PF02187;PF00681;PF00435;,,,,,,,,,DYST_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611] comp144318_c0_seq6,7808,41.2141,0.48304008,0,0,,0,Q03001,Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0009925; GO:0005604; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0031252; GO:0048870; GO:0016023; GO:0031122; GO:0005829; GO:0005789; GO:0030198; GO:0030056; GO:0031581; GO:0016021; GO:0007229; GO:0005882; GO:0045111; GO:0045104; GO:0030011; GO:0015630; GO:0000226; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0042803; GO:0031110; GO:0009611; GO:0008090,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; basal plasma membrane; basement membrane; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cell leading edge; cell motility; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; cytosol; endoplasmic reticulum membrane; extracellular matrix organization; hemidesmosome; hemidesmosome assembly; integral to membrane; integrin-mediated signaling pathway; intermediate filament; intermediate filament cytoskeleton; intermediate filament cytoskeleton organization; maintenance of cell polarity; microtubule cytoskeleton; microtubule cytoskeleton organization; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; response to wounding; retrograde axon cargo transport,PF00307;PF13499;PF02187;PF00681;PF00435;,,,,,,,,,DYST_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611] comp144318_c0_seq8,4592,46.2979,0.46768345,0,0,,0,Q03001,Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0009925; GO:0005604; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0031252; GO:0048870; GO:0016023; GO:0031122; GO:0005829; GO:0005789; GO:0030198; GO:0030056; GO:0031581; GO:0016021; GO:0007229; GO:0005882; GO:0045111; GO:0045104; GO:0030011; GO:0015630; GO:0000226; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0042803; GO:0031110; GO:0009611; GO:0008090,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; basal plasma membrane; basement membrane; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cell leading edge; cell motility; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; cytosol; endoplasmic reticulum membrane; extracellular matrix organization; hemidesmosome; hemidesmosome assembly; integral to membrane; integrin-mediated signaling pathway; intermediate filament; intermediate filament cytoskeleton; intermediate filament cytoskeleton organization; maintenance of cell polarity; microtubule cytoskeleton; microtubule cytoskeleton organization; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; response to wounding; retrograde axon cargo transport,PF00307;PF13499;PF02187;PF00681;PF00435;,0,CHOYP_LOC100118464.1.1,,,,,,,DYST_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611] comp144318_c0_seq9,4616,46.2305,0.46640953,0,0,,2.00E-19,P16546,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)",GO:0030018; GO:0051693; GO:0005509; GO:0032437; GO:0005916; GO:0016328; GO:0033270; GO:0046982; GO:0030507,Z disc; actin filament capping; calcium ion binding; cuticular plate; fascia adherens; lateral plasma membrane; paranode region of axon; protein heterodimerization activity; spectrin binding,PF13499;PF08726;PF00018;PF00435;,,,,,,,,,SPTN1_MOUSE,Mus musculus (Mouse),actin filament capping [GO:0051693] comp144319_c0_seq1,5465,47.5572,0.65726927,0,0,,1.00E-61,Q96SB3,Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin),Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin),GO:0008380; GO:0007015; GO:0005912; GO:0019722; GO:0007050; GO:0016477; GO:0071315; GO:0030864; GO:0016358; GO:0043197; GO:0030175; GO:0046847; GO:0030027; GO:0030308; GO:0005654; GO:0008157; GO:0004864; GO:0000164; GO:0001560; GO:0042127; GO:0007096; GO:2000474; GO:0001932; GO:0032587; GO:0045202,RNA splicing; actin filament organization; adherens junction; calcium-mediated signaling; cell cycle arrest; cell migration; cellular response to morphine; cortical actin cytoskeleton; dendrite development; dendritic spine; filopodium; filopodium assembly; lamellipodium; negative regulation of cell growth; nucleoplasm; protein phosphatase 1 binding; protein phosphatase inhibitor activity; protein phosphatase type 1 complex; regulation of cell growth by extracellular stimulus; regulation of cell proliferation; regulation of exit from mitosis; regulation of opioid receptor signaling pathway; regulation of protein phosphorylation; ruffle membrane; synapse,PF00595;,1.00E-81,CHOYP_PHUM_PHUM305910.2.2,,,,,,,NEB2_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to morphine [GO:0071315]; filopodium assembly [GO:0046847]; modulation of synaptic transmission [GO:0050804]; negative regulation of cell growth [GO:0030308]; neuron projection development [GO:0031175]; regulation of cell growth by extracellular stimulus [GO:0001560]; regulation of cell proliferation [GO:0042127]; regulation of exit from mitosis [GO:0007096]; regulation of opioid receptor signaling pathway [GO:2000474]; RNA splicing [GO:0008380] comp144319_c0_seq2,5606,47.1459,0.64925968,0,0,,6.00E-62,O35274,Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130),Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130),GO:0007015; GO:0005912; GO:0019722; GO:0016477; GO:0071315; GO:0030864; GO:0005737; GO:0016358; GO:0043197; GO:0030175; GO:0046847; GO:0030027; GO:0005634; GO:2000474; GO:0001932; GO:0032587; GO:0045202,actin filament organization; adherens junction; calcium-mediated signaling; cell migration; cellular response to morphine; cortical actin cytoskeleton; cytoplasm; dendrite development; dendritic spine; filopodium; filopodium assembly; lamellipodium; nucleus; regulation of opioid receptor signaling pathway; regulation of protein phosphorylation; ruffle membrane; synapse,PF00595;,6.00E-79,CHOYP_NEB1.1.1,,,,,,,NEB2_RAT,Rattus norvegicus (Rat),actin filament depolymerization [GO:0030042]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to drug [GO:0035690]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to light stimulus [GO:0071482]; cellular response to morphine [GO:0071315]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cerebral cortex development [GO:0021987]; dendrite development [GO:0016358]; developmental process involved in reproduction [GO:0003006]; filopodium assembly [GO:0046847]; hippocampus development [GO:0021766]; learning [GO:0007612]; male mating behavior [GO:0060179]; modulation of synaptic transmission [GO:0050804]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; neuron projection development [GO:0031175]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to actin cortical patch [GO:1904372]; protein localization to actin cytoskeleton [GO:1903119]; protein localization to cell periphery [GO:1990778]; regulation of cell proliferation [GO:0042127]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of protein phosphorylation [GO:0001932]; reproductive system development [GO:0061458]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to clozapine [GO:0097338]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to kainic acid [GO:1904373]; response to L-phenylalanine derivative [GO:1904386]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to prostaglandin E [GO:0034695]; response to steroid hormone [GO:0048545] comp144319_c0_seq5,5379,47.4995,0.65641376,2,9,,5.00E-62,O35274,Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130),Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130),GO:0007015; GO:0005912; GO:0019722; GO:0016477; GO:0071315; GO:0030864; GO:0005737; GO:0016358; GO:0043197; GO:0030175; GO:0046847; GO:0030027; GO:0005634; GO:2000474; GO:0001932; GO:0032587; GO:0045202,actin filament organization; adherens junction; calcium-mediated signaling; cell migration; cellular response to morphine; cortical actin cytoskeleton; cytoplasm; dendrite development; dendritic spine; filopodium; filopodium assembly; lamellipodium; nucleus; regulation of opioid receptor signaling pathway; regulation of protein phosphorylation; ruffle membrane; synapse,PF00595;,1.00E-81,CHOYP_PHUM_PHUM305910.2.2,,,,,,,NEB2_RAT,Rattus norvegicus (Rat),actin filament depolymerization [GO:0030042]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to drug [GO:0035690]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to light stimulus [GO:0071482]; cellular response to morphine [GO:0071315]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cerebral cortex development [GO:0021987]; dendrite development [GO:0016358]; developmental process involved in reproduction [GO:0003006]; filopodium assembly [GO:0046847]; hippocampus development [GO:0021766]; learning [GO:0007612]; male mating behavior [GO:0060179]; modulation of synaptic transmission [GO:0050804]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; neuron projection development [GO:0031175]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to actin cortical patch [GO:1904372]; protein localization to actin cytoskeleton [GO:1903119]; protein localization to cell periphery [GO:1990778]; regulation of cell proliferation [GO:0042127]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of protein phosphorylation [GO:0001932]; reproductive system development [GO:0061458]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to clozapine [GO:0097338]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to kainic acid [GO:1904373]; response to L-phenylalanine derivative [GO:1904386]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to prostaglandin E [GO:0034695]; response to steroid hormone [GO:0048545] comp144321_c0_seq11,1698,34.8057,0.89683316,0,0,,,,,,,,,6.00E-16,CHOYP_LOC100632495.3.11,,,,,,,,, comp144321_c0_seq12,1003,35.5932,1.02318573,0,207,female,,,,,,,,,,3.00E-14,ruditapes_c29662,,,,,,, comp144321_c0_seq8,1672,34.7488,0.91556437,0,0,,,,,,,,,5.00E-16,CHOYP_LOC100632495.3.11,,,,,,,,, comp144323_c1_seq6,1373,29.1333,0.68706907,20,0,,,,,,,,,,,2.00E-11,ruditapes_c1831,,,,,,, comp144323_c1_seq9,3057,39.5486,0.50985083,607,2053,,0,Q86VQ6,Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2),Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2),GO:0050661; GO:0030154; GO:0045454; GO:0009055; GO:0005783; GO:0050660; GO:0007275; GO:0005634; GO:0015035; GO:0007283; GO:0004791,NADP binding; cell differentiation; cell redox homeostasis; electron carrier activity; endoplasmic reticulum; flavin adenine dinucleotide binding; multicellular organismal development; nucleus; protein disulfide oxidoreductase activity; spermatogenesis; thioredoxin-disulfide reductase activity,PF00462;PF07992;PF02852;,0,CHOYP_BRAFLDRAFT_122807.1.1,,,,,,,TRXR3_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp144324_c1_seq1,1476,38.0759,0.39331246,1858,233,,,,,,,,,,,1.00E-72,ruditapes_c23986,,,,,,, comp144324_c2_seq1,2590,43.0116,0.47245158,81,5,,0,B0CM26,Uncharacterized protein C7orf63 homolog,Cilia- and flagella-associated protein 69,,,,,,,,,,,,CG063_PAPAN,Papio anubis (Olive baboon), comp144324_c2_seq2,2527,43.1737,0.51467902,57,0,,,,,,,,,0,CHOYP_BRAFLDRAFT_270517.1.1,,,,,,,,, comp144324_c2_seq4,2299,44.4541,0.48840765,2,0,,0,B0VXE6,Uncharacterized protein C7orf63,Cilia- and flagella-associated protein 69,,,,0,CHOYP_BRAFLDRAFT_270517.1.1,1.00E-30,ruditapes_c23848,,,,,CG063_CALJA,Callithrix jacchus (White-tufted-ear marmoset), comp144325_c1_seq1,1581,44.5288,0.50292246,0,0,,,,,,,,,1.00E-62,CHOYP_BRAFLDRAFT_129914.1.3,,,,,,,,, comp144325_c1_seq2,1593,44.57,0.51118846,0,0,,7.00E-17,Q8IYJ2,Uncharacterized protein C10orf67,"Uncharacterized protein C10orf67, mitochondrial",,,PF15821;PF15852;,,,,,,,,,CJ067_HUMAN,Homo sapiens (Human), comp144325_c1_seq6,1952,41.9057,0.54147996,0,0,,,,,,,,,6.00E-61,CHOYP_LOC100893805.1.1,,,,,,,,, comp144325_c1_seq8,1940,41.8557,0.53408966,0,0,,1.00E-16,Q8IYJ2,Uncharacterized protein C10orf67,"Uncharacterized protein C10orf67, mitochondrial",,,PF15821;PF15852;,1.00E-62,CHOYP_BRAFLDRAFT_129914.1.3,,,,,,,CJ067_HUMAN,Homo sapiens (Human), comp144327_c0_seq1,6441,42.3847,0.64607363,15,0,,0,Q5UQE6,DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II),DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II),GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0046872,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; metal ion binding,PF00204;PF00521;PF02518;PF01751;PF16898;,0,CHOYP_TOP2B.1.1,,,,,,,TOP2_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),DNA topological change [GO:0006265] comp144327_c0_seq2,6308,42.7235,0.63056536,0,0,,0,O42131,"DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)","DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)",GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0006261; GO:0071778; GO:0003682; GO:0042826; GO:0046872; GO:0006312; GO:0005654; GO:0005080; GO:0000712; GO:0000819; GO:0000795,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; DNA-dependent DNA replication; WINAC complex; chromatin binding; histone deacetylase binding; metal ion binding; mitotic recombination; nucleoplasm; protein kinase C binding; resolution of meiotic recombination intermediates; sister chromatid segregation; synaptonemal complex,PF00204;PF00521;PF08070;PF02518;PF01751;PF16898;,,,,,,,,,TOP2B_CHICK,Gallus gallus (Chicken),DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic recombination [GO:0006312]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] comp144327_c0_seq3,6078,42.9747,0.636593,4,4,,0,O42131,"DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)","DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)",GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0006261; GO:0071778; GO:0003682; GO:0042826; GO:0046872; GO:0006312; GO:0005654; GO:0005080; GO:0000712; GO:0000819; GO:0000795,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; DNA-dependent DNA replication; WINAC complex; chromatin binding; histone deacetylase binding; metal ion binding; mitotic recombination; nucleoplasm; protein kinase C binding; resolution of meiotic recombination intermediates; sister chromatid segregation; synaptonemal complex,PF00204;PF00521;PF08070;PF02518;PF01751;PF16898;,0,CHOYP_TOP2B.1.1,,,,,,,TOP2B_CHICK,Gallus gallus (Chicken),DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic recombination [GO:0006312]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] comp144327_c0_seq4,4934,44.0413,0.61648069,9,0,,0,Q5UQE6,DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II),DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II),GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0046872,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; metal ion binding,PF00204;PF00521;PF02518;PF01751;PF16898;,0,CHOYP_TOP2A.1.1,,,,,,,TOP2_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),DNA topological change [GO:0006265] comp144327_c0_seq5,5995,43.4028,0.63701779,0,0,,0,O42131,"DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)","DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)",GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0006261; GO:0071778; GO:0003682; GO:0042826; GO:0046872; GO:0006312; GO:0005654; GO:0005080; GO:0000712; GO:0000819; GO:0000795,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; DNA-dependent DNA replication; WINAC complex; chromatin binding; histone deacetylase binding; metal ion binding; mitotic recombination; nucleoplasm; protein kinase C binding; resolution of meiotic recombination intermediates; sister chromatid segregation; synaptonemal complex,PF00204;PF00521;PF08070;PF02518;PF01751;PF16898;,0,CHOYP_TOP2B.1.1,,,,,,,TOP2B_CHICK,Gallus gallus (Chicken),DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic recombination [GO:0006312]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] comp144327_c0_seq6,5720,43.6189,0.64404425,0,5,,,,,,,,,0,CHOYP_TOP2B.1.1,,,,,,,,, comp144328_c0_seq1,2976,37.8024,0.3300402,1,54,,3.00E-43,Q40469,Eukaryotic initiation factor 4A-6 (eIF-4A-6) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-6) (Fragment),Eukaryotic initiation factor 4A-6 (eIF-4A-6) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-6) (Fragment),GO:0005524; GO:0008026; GO:0003743,ATP binding; ATP-dependent helicase activity; translation initiation factor activity,PF00270;PF00271;,2.00E-38,CHOYP_DDX20.1.3,,,,,,,IF4A6_TOBAC,Nicotiana tabacum (Common tobacco), comp144328_c0_seq3,3977,37.5157,0.37199301,176,1202,,9.00E-159,P0C218,Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (DEAD box protein 20),Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (DEAD box protein 20),GO:0005524; GO:0008026; GO:0003677; GO:0008380; GO:0005737; GO:0006397; GO:0005681,ATP binding; ATP-dependent helicase activity; DNA binding; RNA splicing; cytoplasm; mRNA processing; spliceosomal complex,PF00270;PF00271;,7.00E-108,CHOYP_DDX20.3.3,,,,,,,DDX20_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),RNA secondary structure unwinding [GO:0010501]; spliceosomal snRNP assembly [GO:0000387] comp144329_c1_seq1,397,42.8212,0.63440484,0,0,,8.00E-34,O60566,Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1),Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1),GO:0005524; GO:0005680; GO:0031145; GO:0006915; GO:0051301; GO:0008283; GO:0000940; GO:0000778; GO:0005829; GO:0007091; GO:0005815; GO:0007067; GO:0007094; GO:0051436; GO:0048471; GO:0048015; GO:0004672; GO:0071459; GO:0034501; GO:0004674; GO:0051233; GO:0007051,"ATP binding; anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; apoptotic process; cell division; cell proliferation; condensed chromosome outer kinetochore; condensed nuclear chromosome kinetochore; cytosol; metaphase/anaphase transition of mitotic cell cycle; microtubule organizing center; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; perinuclear region of cytoplasm; phosphatidylinositol-mediated signaling; protein kinase activity; protein localization to chromosome, centromeric region; protein localization to kinetochore; protein serine/threonine kinase activity; spindle midzone; spindle organization",PF08311;PF00069;,,,,,,,,,BUB1B_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; apoptotic process [GO:0006915]; cell division [GO:0051301]; cell proliferation [GO:0008283]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization to kinetochore [GO:0034501]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062] comp144329_c1_seq2,1608,42.2886,0.470318,119,179,,1.00E-78,O60566,Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1),Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1),GO:0005524; GO:0005680; GO:0031145; GO:0006915; GO:0051301; GO:0008283; GO:0000940; GO:0000778; GO:0005829; GO:0007091; GO:0005815; GO:0007067; GO:0007094; GO:0051436; GO:0048471; GO:0048015; GO:0004672; GO:0071459; GO:0034501; GO:0004674; GO:0051233; GO:0007051,"ATP binding; anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; apoptotic process; cell division; cell proliferation; condensed chromosome outer kinetochore; condensed nuclear chromosome kinetochore; cytosol; metaphase/anaphase transition of mitotic cell cycle; microtubule organizing center; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; perinuclear region of cytoplasm; phosphatidylinositol-mediated signaling; protein kinase activity; protein localization to chromosome, centromeric region; protein localization to kinetochore; protein serine/threonine kinase activity; spindle midzone; spindle organization",PF08311;PF00069;,9.00E-13,CHOYP_BUB1B.1.1,,,,,,,BUB1B_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; apoptotic process [GO:0006915]; cell division [GO:0051301]; cell proliferation [GO:0008283]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization to kinetochore [GO:0034501]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062] comp144329_c2_seq1,2869,42.2447,0.44731559,14,60,,5.00E-06,Q1ZXI5,Probable serine/threonine-protein kinase DDB_G0278845 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0278845 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,Y1558_DICDI,Dictyostelium discoideum (Slime mold),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] comp144329_c2_seq2,2845,42.2847,0.42652092,32,44,,1.00E-71,O43683,Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A),Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A),GO:0005524; GO:0006915; GO:0051301; GO:0008283; GO:0007059; GO:0000777; GO:0000780; GO:0005829; GO:0007067; GO:0000278; GO:0007094; GO:0019048; GO:0004672; GO:0004674; GO:0007063,"ATP binding; apoptotic process; cell division; cell proliferation; chromosome segregation; condensed chromosome kinetochore; condensed nuclear chromosome, centromeric region; cytosol; mitosis; mitotic cell cycle; mitotic spindle assembly checkpoint; modulation by virus of host morphology or physiology; protein kinase activity; protein serine/threonine kinase activity; regulation of sister chromatid cohesion",PF08311;PF00069;,2.00E-36,CHOYP_LOC100543305.1.1,,,,,,,BUB1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of chromosome segregation [GO:0051983]; regulation of sister chromatid cohesion [GO:0007063]; sister chromatid cohesion [GO:0007062]; spindle assembly checkpoint [GO:0071173]; viral process [GO:0016032] comp144330_c0_seq1,5469,48.5281,0.41504906,6,0,,0,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,0,CHOYP_PHUM_PHUM226120.3.7,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp144330_c0_seq2,4402,48.9777,0.42158506,1,1,,4.00E-57,P16419,"Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)","Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)",GO:0007155; GO:0032982,cell adhesion; myosin filament,PF00041;PF07679;,,,,,,,,,MYPC2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155] comp144330_c0_seq3,5493,48.6073,0.42119933,12,29,,0,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,0,CHOYP_PHUM_PHUM226120.3.7,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp144330_c0_seq4,4378,48.9493,0.41677453,0,0,,1.00E-57,Q00872,"Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)","Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)",GO:0007155; GO:0005829; GO:0030049; GO:0030016; GO:0032982; GO:0008307; GO:0031432,cell adhesion; cytosol; muscle filament sliding; myofibril; myosin filament; structural constituent of muscle; titin binding,PF00041;PF07679;,,,,,,,,,MYPC1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp144330_c0_seq5,1725,49.2174,0.3639856,4,3,,4.00E-141,Q23551,Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),Twitchin (EC 2.7.11.1) (Uncoordinated protein 22),GO:0031672; GO:0005524; GO:0046872; GO:0004674,A band; ATP binding; metal ion binding; protein serine/threonine kinase activity,PF00041;PF07679;PF00069;,,,,,,,,,UNC22_CAEEL,Caenorhabditis elegans,negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] comp144332_c0_seq1,8229,43.2009,0.47190368,6,53,,5.00E-142,Q8TDI0,Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5),Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5),GO:0005524; GO:0008026; GO:0003677; GO:0016568; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"ATP binding; ATP-dependent helicase activity; DNA binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;,0,CHOYP_LOC100115939.1.1,2.00E-72,ruditapes_c18910,,,,,CHD5_HUMAN,Homo sapiens (Human),"cerebral cortex neuron differentiation [GO:0021895]; histone H3-K27 trimethylation [GO:0098532]; histone H4 acetylation [GO:0043967]; negative regulation of cell proliferation [GO:0008285]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of transcription involved in cell fate commitment [GO:0060850]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; transcription, DNA-templated [GO:0006351]" comp144332_c0_seq3,9571,42.4825,0.48447159,384,3097,,1.00E-141,Q8TDI0,Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5),Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5),GO:0005524; GO:0008026; GO:0003677; GO:0016568; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"ATP binding; ATP-dependent helicase activity; DNA binding; chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;,,,,,,,,,CHD5_HUMAN,Homo sapiens (Human),"cerebral cortex neuron differentiation [GO:0021895]; histone H3-K27 trimethylation [GO:0098532]; histone H4 acetylation [GO:0043967]; negative regulation of cell proliferation [GO:0008285]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of transcription involved in cell fate commitment [GO:0060850]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; transcription, DNA-templated [GO:0006351]" comp144335_c2_seq1,3138,32.3136,0.52985147,0,0,,2.00E-37,Q20496,Probable rho GDP-dissociation inhibitor (Rho GDI),Probable rho GDP-dissociation inhibitor (Rho GDI),GO:0005096; GO:0005094; GO:0005829; GO:0016020; GO:0043547,GTPase activator activity; Rho GDP-dissociation inhibitor activity; cytosol; membrane; positive regulation of GTPase activity,PF02115;,,,,,,,,,GDIR_CAEEL,Caenorhabditis elegans, comp144335_c2_seq10,2724,32.0852,0.56388591,12,57,,1.00E-37,Q20496,Probable rho GDP-dissociation inhibitor (Rho GDI),Probable rho GDP-dissociation inhibitor (Rho GDI),GO:0005096; GO:0005094; GO:0005829; GO:0016020; GO:0043547,GTPase activator activity; Rho GDP-dissociation inhibitor activity; cytosol; membrane; positive regulation of GTPase activity,PF02115;,,,,,,,,,GDIR_CAEEL,Caenorhabditis elegans, comp144335_c2_seq15,2686,32.1668,0.55548249,13,39,,1.00E-37,Q20496,Probable rho GDP-dissociation inhibitor (Rho GDI),Probable rho GDP-dissociation inhibitor (Rho GDI),GO:0005096; GO:0005094; GO:0005829; GO:0016020; GO:0043547,GTPase activator activity; Rho GDP-dissociation inhibitor activity; cytosol; membrane; positive regulation of GTPase activity,PF02115;,,,,,,,,,GDIR_CAEEL,Caenorhabditis elegans, comp144338_c0_seq1,2567,41.0206,0.89727477,0,6,,8.00E-42,O15374,Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,2.00E-12,CHOYP_DANA_MCT1.1.1,,,,,,,MOT5_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp144338_c0_seq2,2863,39.9581,0.90058739,0,0,,5.00E-38,Q8R0M8,Monocarboxylate transporter 5 (MCT 5),Monocarboxylate transporter 5 (MCT 5),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT5_MOUSE,Mus musculus (Mouse),plasma membrane lactate transport [GO:0035879] comp144338_c0_seq6,2580,41.124,0.8872339,0,0,,1.00E-44,Q7RTX9,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,2.00E-12,CHOYP_DANA_MCT1.1.1,,,,,,,MOT14_HUMAN,Homo sapiens (Human), comp144339_c1_seq2,1290,32.8682,0.77618734,71,679,,,,,,,,,,,7.00E-11,ruditapes_c21964,,,,,,, comp144341_c0_seq1,4157,41.7128,0.40408547,9,24,,4.00E-84,Q9NZB2,Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A),Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A),GO:0003723; GO:0005737; GO:0005886,RNA binding; cytoplasm; plasma membrane,,,,,,,,,,F120A_HUMAN,Homo sapiens (Human), comp144341_c0_seq2,6272,38.2812,0.41937664,2,29,,2.00E-82,Q6DEZ2,Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A),Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A),GO:0003723; GO:0005737; GO:0005886,RNA binding; cytoplasm; plasma membrane,,3.00E-127,CHOYP_LOC100877311.1.1,,,,,,,F120A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp144341_c0_seq3,7188,37.1452,0.40907892,242,1366,,8.00E-83,Q9NZB2,Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A),Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A),GO:0003723; GO:0005737; GO:0005886,RNA binding; cytoplasm; plasma membrane,,,,,,,,,,F120A_HUMAN,Homo sapiens (Human), comp144341_c0_seq4,4095,41.9048,0.40070549,3,1,,1.00E-83,Q6DEZ2,Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A),Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A),GO:0003723; GO:0005737; GO:0005886,RNA binding; cytoplasm; plasma membrane,,2.00E-127,CHOYP_LOC100877311.1.1,,,,,,,F120A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp144341_c0_seq7,2855,44.5184,0.35095854,0,0,,1.00E-85,Q9NZB2,Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A),Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A),GO:0003723; GO:0005737; GO:0005886,RNA binding; cytoplasm; plasma membrane,,1.00E-127,CHOYP_LOC100877311.1.1,,,,,,,F120A_HUMAN,Homo sapiens (Human), comp144342_c0_seq1,1357,35.7406,0.39231568,2,1,,,,,,,,,1.00E-11,CHOYP_BPTF.1.1,,,,,,,,, comp144342_c0_seq10,1989,38.009,0.47690644,0,0,,7.00E-122,Q12830,Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),GO:0016589; GO:0009952; GO:0007420; GO:0006338; GO:0005737; GO:0001892; GO:0007492; GO:0000122; GO:0045893; GO:0043565; GO:0008134; GO:0006351; GO:0008270,"NURF complex; anterior/posterior pattern specification; brain development; chromatin remodeling; cytoplasm; embryonic placenta development; endoderm development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF00628;PF15612;PF15613;,1.00E-113,CHOYP_BPTF.1.1,,,,,,,BPTF_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]" comp144342_c0_seq11,2700,40.7037,0.36097807,0,0,,1.00E-10,Q09698,Uncharacterized protein C2F7.07c,Uncharacterized protein C2F7.07c,GO:0032221; GO:0006338; GO:0016575; GO:0019787; GO:0005819; GO:0008270,Rpd3S complex; chromatin remodeling; histone deacetylation; small conjugating protein ligase activity; spindle; zinc ion binding,PF00628;,,,,,,,,,YA27_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]" comp144342_c0_seq2,5885,39.4223,0.38267039,87,27,,3.00E-10,Q09698,Uncharacterized protein C2F7.07c,Uncharacterized protein C2F7.07c,GO:0032221; GO:0006338; GO:0016575; GO:0019787; GO:0005819; GO:0008270,Rpd3S complex; chromatin remodeling; histone deacetylation; small conjugating protein ligase activity; spindle; zinc ion binding,PF00628;,,,,,,,,,YA27_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]" comp144342_c0_seq3,5584,38.9148,0.38492621,4,0,,6.00E-115,Q12830,Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),GO:0016589; GO:0009952; GO:0007420; GO:0006338; GO:0005737; GO:0001892; GO:0007492; GO:0000122; GO:0045893; GO:0043565; GO:0008134; GO:0006351; GO:0008270,"NURF complex; anterior/posterior pattern specification; brain development; chromatin remodeling; cytoplasm; embryonic placenta development; endoderm development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF00628;PF15612;PF15613;,,,,,,,,,BPTF_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]" comp144342_c0_seq4,3551,40.0169,0.43348275,0,0,,7.00E-118,Q12830,Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen),GO:0016589; GO:0009952; GO:0007420; GO:0006338; GO:0005737; GO:0001892; GO:0007492; GO:0000122; GO:0045893; GO:0043565; GO:0008134; GO:0006351; GO:0008270,"NURF complex; anterior/posterior pattern specification; brain development; chromatin remodeling; cytoplasm; embryonic placenta development; endoderm development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription factor binding; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF00628;PF15612;PF15613;,2.00E-113,CHOYP_BPTF.1.1,,,,,,,BPTF_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]" comp144342_c0_seq5,4450,38.8989,0.32678196,8,0,,2.00E-10,Q09698,Uncharacterized protein C2F7.07c,Uncharacterized protein C2F7.07c,GO:0032221; GO:0006338; GO:0016575; GO:0019787; GO:0005819; GO:0008270,Rpd3S complex; chromatin remodeling; histone deacetylation; small conjugating protein ligase activity; spindle; zinc ion binding,PF00628;,,,,,,,,,YA27_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]" comp144342_c0_seq7,3371,44.1709,0.26792159,280,149,,2.00E-21,Q03330,Histone acetyltransferase GCN5 (EC 2.3.1.48),Histone acetyltransferase GCN5 (EC 2.3.1.48),GO:0005671; GO:0010484; GO:0000124; GO:0046695; GO:0000775; GO:0005829; GO:0070577; GO:0032968; GO:0034401; GO:0003713; GO:0006351,"Ada2/Gcn5/Ada3 transcription activator complex; H3 histone acetyltransferase activity; SAGA complex; SLIK (SAGA-like) complex; chromosome, centromeric region; cytosol; histone acetyl-lysine binding; positive regulation of transcription elongation from RNA polymerase II promoter; regulation of transcription by chromatin organization; transcription coactivator activity; transcription, DNA-dependent",PF00583;PF00439;,9.00E-17,CHOYP_contig_013909,,,,,,,GCN5_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"chromatin modification [GO:0016568]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription, DNA-templated [GO:0006351]" comp144342_c0_seq8,1138,38.1371,0.30867233,0,0,,,,,,,,,5.00E-103,CHOYP_BPTF.1.1,,,,,,,,, comp144342_c0_seq9,1606,38.8543,0.30031158,0,0,,6.00E-22,Q03330,Histone acetyltransferase GCN5 (EC 2.3.1.48),Histone acetyltransferase GCN5 (EC 2.3.1.48),GO:0005671; GO:0010484; GO:0000124; GO:0046695; GO:0000775; GO:0005829; GO:0070577; GO:0032968; GO:0034401; GO:0003713; GO:0006351,"Ada2/Gcn5/Ada3 transcription activator complex; H3 histone acetyltransferase activity; SAGA complex; SLIK (SAGA-like) complex; chromosome, centromeric region; cytosol; histone acetyl-lysine binding; positive regulation of transcription elongation from RNA polymerase II promoter; regulation of transcription by chromatin organization; transcription coactivator activity; transcription, DNA-dependent",PF00583;PF00439;,,,,,,,,,GCN5_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"chromatin modification [GO:0016568]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription, DNA-templated [GO:0006351]" comp144343_c3_seq1,4216,42.8605,0.50040195,0,0,,,,,,,,,2.00E-114,CHOYP_RAD50.3.4,,,,,,,,, comp144343_c3_seq3,4228,42.7862,0.48967938,25,21,,0,Q92878,DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-),DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-),GO:0005524; GO:0003677; GO:0032508; GO:0030870; GO:0000724; GO:0000784; GO:0004518; GO:0090305; GO:0005654; GO:0033674; GO:0031954; GO:0045120; GO:0030674; GO:0007131; GO:0000019; GO:0035861; GO:0007004; GO:0008270,"ATP binding; DNA binding; DNA duplex unwinding; Mre11 complex; double-strand break repair via homologous recombination; nuclear chromosome, telomeric region; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleoplasm; positive regulation of kinase activity; positive regulation of protein autophosphorylation; pronucleus; protein binding, bridging; reciprocal meiotic recombination; regulation of mitotic recombination; site of double-strand break; telomere maintenance via telomerase; zinc ion binding",PF04423;,2.00E-114,CHOYP_RAD50.3.4,,,,,,,RAD50_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of telomere capping [GO:1904354]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860]; viral process [GO:0016032] comp144343_c3_seq4,4163,42.8297,0.50807673,0,0,,1.00E-117,Q92878,DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-),DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-),GO:0005524; GO:0003677; GO:0032508; GO:0030870; GO:0000724; GO:0000784; GO:0004518; GO:0090305; GO:0005654; GO:0033674; GO:0031954; GO:0045120; GO:0030674; GO:0007131; GO:0000019; GO:0035861; GO:0007004; GO:0008270,"ATP binding; DNA binding; DNA duplex unwinding; Mre11 complex; double-strand break repair via homologous recombination; nuclear chromosome, telomeric region; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleoplasm; positive regulation of kinase activity; positive regulation of protein autophosphorylation; pronucleus; protein binding, bridging; reciprocal meiotic recombination; regulation of mitotic recombination; site of double-strand break; telomere maintenance via telomerase; zinc ion binding",PF04423;,,,5.00E-19,ruditapes_c19538,,,,,RAD50_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of telomere capping [GO:1904354]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860]; viral process [GO:0016032] comp144344_c0_seq2,3473,43.9965,0.71890825,281,550,,0,P97603,Neogenin (Fragment),Neogenin (Fragment),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;PF13895;PF06583;,,,,,,,,,NEO1_RAT,Rattus norvegicus (Rat),axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; negative regulation of neuron death [GO:1901215]; positive regulation of BMP signaling pathway [GO:0030513] comp144344_c0_seq4,2428,45.5519,0.54281479,153,280,,1.00E-16,Q2Q0I9,Fibronectin type III domain-containing protein 1 (Activator of G-protein signaling 8),Fibronectin type III domain-containing protein 1 (Activator of G-protein signaling 8),GO:0005911; GO:0071456; GO:0005576; GO:0031966; GO:0005886; GO:0010666; GO:0001934; GO:0051223,cell-cell junction; cellular response to hypoxia; extracellular region; mitochondrial membrane; plasma membrane; positive regulation of cardiac muscle cell apoptotic process; positive regulation of protein phosphorylation; regulation of protein transport,PF00041;,1.00E-25,CHOYP_NEO1.3.3,,,,,,,FNDC1_RAT,Rattus norvegicus (Rat),cellular response to hypoxia [GO:0071456]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of protein phosphorylation [GO:0001934]; regulation of protein transport [GO:0051223] comp144345_c1_seq1,4329,42.1113,0.37525189,59,13,,,,,,,,,2.00E-40,CHOYP_NCAPG.1.1,,,,,,,,, comp144345_c1_seq2,5560,42.0863,0.37405539,301,266,,0,Q9YHB5,Condensin complex subunit 3 (Chromosome assembly protein xCAP-G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (Non-SMC condensin I complex subunit G),Condensin complex subunit 3 (Chromosome assembly protein xCAP-G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (Non-SMC condensin I complex subunit G),GO:0051301; GO:0000796; GO:0005829; GO:0007076; GO:0005634,cell division; condensin complex; cytosol; mitotic chromosome condensation; nucleus,PF12719;,2.00E-40,CHOYP_NCAPG.1.1,,,,,,,CND3_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp144347_c0_seq1,3640,45.0549,0.63521349,0,0,,0,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,1.00E-92,CHOYP_PB1.2.6,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq11,1618,43.9431,0.57656717,0,0,,,,,,,,,1.00E-23,CHOYP_PHUM_PHUM244090.1.1,,,,,,,,, comp144347_c0_seq12,3672,44.744,0.64948962,0,0,,8.00E-162,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,1.00E-92,CHOYP_PB1.2.6,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq14,3766,45.5125,0.61149265,0,0,,2.00E-15,Q9UTN6,Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21),Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21),GO:0005524; GO:0004003; GO:0003677; GO:0016586; GO:0006338; GO:0000991; GO:0000790,ATP binding; ATP-dependent DNA helicase activity; DNA binding; RSC complex; chromatin remodeling; core RNA polymerase II binding transcription factor activity; nuclear chromatin,PF00439;PF00271;PF07529;PF14619;PF00176;,,,,,,,,,SNF21_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338]; transcription from RNA polymerase II promoter [GO:0006366] comp144347_c0_seq15,3595,45.1182,0.63051942,14,10,,0,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,2.00E-114,CHOYP_PB1.2.6,1.00E-37,ruditapes_c29530,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq17,1309,40.1833,0.62507266,20,0,,,,,,,,,1.00E-23,CHOYP_PHUM_PHUM244090.1.1,,,,,,,,, comp144347_c0_seq18,1960,44.1327,0.65092316,0,0,,1.00E-15,Q9NR48,Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H),Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H),GO:0003677; GO:0006323; GO:0005794; GO:0007267; GO:0005694; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0005923; GO:0006366; GO:0008270,"DNA binding; DNA packaging; Golgi apparatus; cell-cell signaling; chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; tight junction; transcription from RNA polymerase II promoter; zinc ion binding",PF01426;PF00439;PF00856;,1.00E-12,CHOYP_PB1.1.6,,,,,,,ASH1L_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; DNA packaging [GO:0006323]; histone H3-K36 dimethylation [GO:0097676]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp144347_c0_seq19,2571,45.4687,0.61007846,0,0,,9.00E-08,O44757,Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59),Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59),GO:0003677; GO:0001715; GO:0009792; GO:0048566; GO:0034968; GO:0018024; GO:0040011; GO:0002119; GO:0005634; GO:0018991; GO:0045944; GO:0040014; GO:0045138; GO:0006351; GO:0008270,"DNA binding; ectodermal cell fate specification; embryo development ending in birth or egg hatching; embryonic digestive tract development; histone lysine methylation; histone-lysine N-methyltransferase activity; locomotion; nematode larval development; nucleus; oviposition; positive regulation of transcription from RNA polymerase II promoter; regulation of multicellular organism growth; tail tip morphogenesis; transcription, DNA-dependent; zinc ion binding",PF01426;PF00628;PF00856;,,,,,,,,,LIN59_CAEEL,Caenorhabditis elegans,"ectodermal cell fate specification [GO:0001715]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq2,3679,44.9307,0.62649334,5,0,,1.00E-14,Q8K1P7,Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),GO:0005524; GO:0043044; GO:0003677; GO:0016514; GO:0004386; GO:0071565; GO:0007399; GO:0071564; GO:0006337; GO:0032403; GO:0006355; GO:0003714; GO:0006351,"ATP binding; ATP-dependent chromatin remodeling; DNA binding; SWI/SNF complex; helicase activity; nBAF complex; nervous system development; npBAF complex; nucleosome disassembly; protein complex binding; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;,,,,,,,,,SMCA4_RAT,Rattus norvegicus (Rat),"ATP-dependent chromatin remodeling [GO:0043044]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq20,3634,45.1018,0.62963654,0,0,,0,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,2.00E-114,CHOYP_PB1.2.6,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq24,1178,49.6604,0.59285072,0,0,,,,,,,,,4.00E-22,CHOYP_PB1.6.6,,,,,,,,, comp144347_c0_seq27,1492,42.6944,0.63286438,0,0,,,,,,,,,1.00E-23,CHOYP_PHUM_PHUM244090.1.1,,,,,,,,, comp144347_c0_seq28,1024,46.2891,0.56574433,0,0,,,,,,,,,6.00E-13,CHOYP_PB1.1.6,,,,,,,,, comp144347_c0_seq29,3721,45.6329,0.61053973,0,0,,0,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,2.00E-114,CHOYP_PB1.2.6,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq3,1150,47.6522,0.50598837,0,0,,,,,,,,,4.00E-22,CHOYP_PB1.6.6,,,,,,,,, comp144347_c0_seq31,3804,45.4522,0.60700128,0,0,,2.00E-15,Q9UTN6,Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21),Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21),GO:0005524; GO:0004003; GO:0003677; GO:0016586; GO:0006338; GO:0000991; GO:0000790,ATP binding; ATP-dependent DNA helicase activity; DNA binding; RSC complex; chromatin remodeling; core RNA polymerase II binding transcription factor activity; nuclear chromatin,PF00439;PF00271;PF07529;PF14619;PF00176;,,,,,,,,,SNF21_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),chromatin remodeling [GO:0006338]; transcription from RNA polymerase II promoter [GO:0006366] comp144347_c0_seq32,1999,44.022,0.64145357,0,0,,5.00E-14,Q9VW15,Histone-lysine N-methyltransferase ash1 (EC 2.1.1.43) (Absent small and homeotic disks protein 1) (Lysine N-methyltransferase 2H),Histone-lysine N-methyltransferase ash1 (EC 2.1.1.43) (Absent small and homeotic disks protein 1) (Lysine N-methyltransferase 2H),GO:0003677; GO:0048096; GO:0001700; GO:0042800; GO:0046974; GO:0042799; GO:0005634; GO:0048477; GO:0018991; GO:0003727; GO:0006351; GO:0035327; GO:0008270,"DNA binding; chromatin-mediated maintenance of transcription; embryonic development via the syncytial blastoderm; histone methyltransferase activity (H3-K4 specific); histone methyltransferase activity (H3-K9 specific); histone methyltransferase activity (H4-K20 specific); nucleus; oogenesis; oviposition; single-stranded RNA binding; transcription, DNA-dependent; transcriptionally active chromatin; zinc ion binding",PF01426;PF00856;,2.00E-23,CHOYP_PHUM_PHUM244090.1.1,,,,,,,ASH1_DROME,Drosophila melanogaster (Fruit fly),"chromatin-mediated maintenance of transcription [GO:0048096]; embryonic development via the syncytial blastoderm [GO:0001700]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; negative regulation of histone H3-K27 methylation [GO:0061086]; oogenesis [GO:0048477]; oviposition [GO:0018991]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq33,464,32.5431,1.01124065,0,0,,,,,,,,,,,7.00E-25,ruditapes_c37018,,,,,,, comp144347_c0_seq34,3634,44.7991,0.65466061,0,0,,0,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,1.00E-92,CHOYP_PB1.2.6,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq35,2441,44.0803,0.59294882,0,0,,5.00E-14,Q06488,Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2),Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2),GO:0043044; GO:0003677; GO:0016586; GO:0000724; GO:0006303; GO:0006337; GO:0006276; GO:0042173; GO:0006355; GO:0007062; GO:0030435; GO:0006368,"ATP-dependent chromatin remodeling; DNA binding; RSC complex; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end joining; nucleosome disassembly; plasmid maintenance; regulation of sporulation resulting in formation of a cellular spore; regulation of transcription, DNA-dependent; sister chromatid cohesion; sporulation resulting in formation of a cellular spore; transcription elongation from RNA polymerase II promoter",PF01426;PF00439;,,,,,,,,,RSC2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"ATP-dependent chromatin remodeling [GO:0043044]; chromosome segregation [GO:0007059]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleosome disassembly [GO:0006337]; plasmid maintenance [GO:0006276]; regulation of sporulation resulting in formation of a cellular spore [GO:0042173]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid cohesion [GO:0007062]; sporulation resulting in formation of a cellular spore [GO:0030435]; transcription elongation from RNA polymerase II promoter [GO:0006368]; UV-damage excision repair [GO:0070914]" comp144347_c0_seq36,1217,49.3016,0.58216659,0,0,,,,,,,,,4.00E-22,CHOYP_PB1.6.6,,,,,,,,, comp144347_c0_seq37,3627,44.858,0.64883712,0,0,,1.00E-165,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,,,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq5,2486,43.926,0.59448141,0,0,,,,,,,,,2.00E-23,CHOYP_PHUM_PHUM244090.1.1,,,,,,,,, comp144347_c0_seq6,3589,44.915,0.65403741,0,0,,0,Q86U86,Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D),GO:0003677; GO:0003682; GO:0006338; GO:0007507; GO:0000776; GO:0007067; GO:0008285; GO:0000228; GO:0001890; GO:0006355; GO:0006351,"DNA binding; chromatin binding; chromatin remodeling; heart development; kinetochore; mitosis; negative regulation of cell proliferation; nuclear chromosome; placenta development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;PF00439;PF00505;,2.00E-114,CHOYP_PB1.2.6,,,,,,,PB1_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq7,3759,45.5706,0.60602919,0,0,,1.00E-14,Q8K1P7,Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4),GO:0005524; GO:0043044; GO:0003677; GO:0016514; GO:0004386; GO:0071565; GO:0007399; GO:0071564; GO:0006337; GO:0032403; GO:0006355; GO:0003714; GO:0006351,"ATP binding; ATP-dependent chromatin remodeling; DNA binding; SWI/SNF complex; helicase activity; nBAF complex; nervous system development; npBAF complex; nucleosome disassembly; protein complex binding; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;,,,,,,,,,SMCA4_RAT,Rattus norvegicus (Rat),"ATP-dependent chromatin remodeling [GO:0043044]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]" comp144347_c0_seq8,2308,46.0572,0.59686911,0,0,,1.00E-14,Q9NR48,Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H),Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H),GO:0003677; GO:0006323; GO:0005794; GO:0007267; GO:0005694; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0005923; GO:0006366; GO:0008270,"DNA binding; DNA packaging; Golgi apparatus; cell-cell signaling; chromosome; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; tight junction; transcription from RNA polymerase II promoter; zinc ion binding",PF01426;PF00439;PF00856;,1.00E-25,CHOYP_PB1.2.6,,,,,,,ASH1L_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; DNA packaging [GO:0006323]; histone H3-K36 dimethylation [GO:0097676]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366] comp144347_c0_seq9,1304,50.5368,0.54155402,0,0,,,,,,,,,5.00E-22,CHOYP_PB1.6.6,,,,,,,,, comp144348_c0_seq1,14086,47.6501,0.43508288,3408,6574,,0,Q9JHU4,"Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)","Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)",GO:0005524; GO:0006200; GO:0016887; GO:0005794; GO:0005858; GO:0005813; GO:0003341; GO:0005737; GO:0033962; GO:0070062; GO:0030175; GO:0005874; GO:0003777; GO:0034063; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; Golgi apparatus; axonemal dynein complex; centrosome; cilium movement; cytoplasm; cytoplasmic mRNA processing body assembly; extracellular vesicular exosome; filopodium; microtubule; microtubule motor activity; stress granule assembly; transport,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC1.1.1,2.00E-106,ruditapes_c29888,,,,,DYHC1_MOUSE,Mus musculus (Mouse),cilium movement [GO:0003341]; cytoplasmic mRNA processing body assembly [GO:0033962]; establishment of spindle localization [GO:0051293]; stress granule assembly [GO:0034063]; transport [GO:0006810] comp144350_c0_seq2,2423,47.792,0.48025224,754,187,,0,Q9EPU0,Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (mUpf1),Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (mUpf1),GO:0005524; GO:0004004; GO:0003677; GO:0006281; GO:0006260; GO:0003723; GO:0000785; GO:0003682; GO:0000932; GO:0009048; GO:0071044; GO:0000184; GO:0005634; GO:0006449; GO:0008270,"ATP binding; ATP-dependent RNA helicase activity; DNA binding; DNA repair; DNA replication; RNA binding; chromatin; chromatin binding; cytoplasmic mRNA processing body; dosage compensation by inactivation of X chromosome; histone mRNA catabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; regulation of translational termination; zinc ion binding",PF09416;,0,CHOYP_RENT1.1.1,,,,,,,RENT1_MOUSE,Mus musculus (Mouse),"3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; histone mRNA catabolic process [GO:0071044]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of translational termination [GO:0006449]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]" comp144350_c0_seq3,3164,41.182,0.39612954,1,29,,1.00E-17,Q9URU2,DNA replication ATP-dependent helicase/nuclease dna2 [Includes: DNA replication nuclease dna2 (EC 3.1.-.-); DNA replication ATP-dependent helicase dna2 (EC 3.6.4.12)],DNA replication ATP-dependent helicase/nuclease dna2 [Includes: DNA replication nuclease dna2 (EC 3.1.-.-); DNA replication ATP-dependent helicase dna2 (EC 3.6.4.12)],GO:0051539; GO:0017108; GO:0005524; GO:0004003; GO:0006281; GO:0043137; GO:0005829; GO:0004527; GO:0031573; GO:0046872; GO:0000784; GO:0043596; GO:0071932; GO:0043142; GO:0035861; GO:0031860; GO:0042162,"4 iron, 4 sulfur cluster binding; 5'-flap endonuclease activity; ATP binding; ATP-dependent DNA helicase activity; DNA repair; DNA replication, removal of RNA primer; cytosol; exonuclease activity; intra-S DNA damage checkpoint; metal ion binding; nuclear chromosome, telomeric region; nuclear replication fork; replication fork reversal; single-stranded DNA-dependent ATPase activity; site of double-strand break; telomeric 3' overhang formation; telomeric DNA binding",PF01930;PF08696;,,,,,,,,,DNA2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),DNA repair [GO:0006281]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; removal of RNA primer involved in mitotic DNA replication [GO:1903469]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860] comp144350_c0_seq4,1868,47.2698,0.42189195,0,0,,4.00E-111,Q92900,Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1),Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1),GO:0005524; GO:0004004; GO:0003677; GO:0006281; GO:0006260; GO:0003723; GO:0000785; GO:0003682; GO:0000932; GO:0005829; GO:0009048; GO:0035145; GO:0010467; GO:0071044; GO:0006406; GO:0000184; GO:0006449; GO:0044530; GO:0008270,"ATP binding; ATP-dependent RNA helicase activity; DNA binding; DNA repair; DNA replication; RNA binding; chromatin; chromatin binding; cytoplasmic mRNA processing body; cytosol; dosage compensation by inactivation of X chromosome; exon-exon junction complex; gene expression; histone mRNA catabolic process; mRNA export from nucleus; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of translational termination; supraspliceosomal complex; zinc ion binding",PF09416;,,,,,,,,,RENT1_HUMAN,Homo sapiens (Human),"3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; histone mRNA catabolic process [GO:0071044]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of translational termination [GO:0006449]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]" comp144350_c0_seq5,3184,41.1432,0.39423476,23,18,,4.00E-93,Q9VYS3,Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-),Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-),GO:0005524; GO:0003677; GO:0071456; GO:0005737; GO:0004386; GO:0000184; GO:2000624; GO:0008270,"ATP binding; DNA binding; cellular response to hypoxia; cytoplasm; helicase activity; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; zinc ion binding",PF09416;,0,CHOYP_RENT1.1.1,,,,,,,RENT1_DROME,Drosophila melanogaster (Fruit fly),"cellular response to hypoxia [GO:0071456]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000624]" comp144353_c0_seq1,2158,36.747,0.4743155,0,17,,4.00E-84,Q497V5,S1 RNA-binding domain-containing protein 1,S1 RNA-binding domain-containing protein 1,GO:0003723; GO:0016788; GO:0006139,"RNA binding; hydrolase activity, acting on ester bonds; nucleobase-containing compound metabolic process",PF00575;PF09371;PF16921;,,,,,,,,,SRBD1_MOUSE,Mus musculus (Mouse),nucleobase-containing compound metabolic process [GO:0006139] comp144353_c0_seq3,2121,36.728,0.46979039,6,21,,4.00E-11,P0CR72,Transcription elongation factor SPT6 (Chromatin elongation factor SPT6),Transcription elongation factor SPT6 (Chromatin elongation factor SPT6),GO:0003677; GO:0003723; GO:0016788; GO:0005634; GO:0032784; GO:0006357; GO:0006351,"DNA binding; RNA binding; hydrolase activity, acting on ester bonds; nucleus; regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent",PF14878;PF14635;PF14641;PF14633;PF14632;PF14639;,,,,,,,,,SPT6_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),chromatin maintenance [GO:0070827]; chromatin silencing at centromere [GO:0030702]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; CLRC ubiquitin ligase complex localization to heterochromatin [GO:0044382]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of histone exchange [GO:1900050]; negative regulation of histone H3-K14 acetylation [GO:0071441]; nucleosome positioning [GO:0016584]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; regulation of extent of heterochromatin assembly [GO:0031454]; regulation of histone H3-K36 methylation [GO:0000414]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243] comp144353_c0_seq4,2177,36.7938,0.46912902,0,0,,4.00E-91,Q8N5C6,S1 RNA-binding domain-containing protein 1,S1 RNA-binding domain-containing protein 1,GO:0003723; GO:0016788; GO:0006139,"RNA binding; hydrolase activity, acting on ester bonds; nucleobase-containing compound metabolic process",PF00575;PF09371;PF16921;,1.00E-25,CHOYP_BRAFLDRAFT_123927.1.1,,,,,,,SRBD1_HUMAN,Homo sapiens (Human),nucleobase-containing compound metabolic process [GO:0006139] comp144353_c0_seq6,1391,41.9123,0.29752081,73,335,,1.00E-73,Q497V5,S1 RNA-binding domain-containing protein 1,S1 RNA-binding domain-containing protein 1,GO:0003723; GO:0016788; GO:0006139,"RNA binding; hydrolase activity, acting on ester bonds; nucleobase-containing compound metabolic process",PF00575;PF09371;PF16921;,,,,,,,,,SRBD1_MOUSE,Mus musculus (Mouse),nucleobase-containing compound metabolic process [GO:0006139] comp144353_c0_seq7,2213,36.6923,0.44979232,0,0,,6.00E-06,Q3MNT0,Transcription elongation factor SPT6 (Chromatin elongation factor SPT6),Transcription elongation factor SPT6 (Chromatin elongation factor SPT6),GO:0003677; GO:0009267; GO:0036180; GO:0036170; GO:0016788; GO:0005634; GO:1900445; GO:1900436; GO:0032784; GO:0006357; GO:0006368,"DNA binding; cellular response to starvation; filamentous growth of a population of unicellular organisms in response to biotic stimulus; filamentous growth of a population of unicellular organisms in response to starvation; hydrolase activity, acting on ester bonds; nucleus; positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus; positive regulation of filamentous growth of a population of unicellular organisms in response to starvation; regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter",PF14878;PF14635;PF14641;PF14633;PF14632;PF14639;,2.00E-22,CHOYP_BRAFLDRAFT_123927.1.1,,,,,,,SPT6_CANAL,Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast),cellular response to starvation [GO:0009267]; chromatin maintenance [GO:0070827]; chromatin organization involved in regulation of transcription [GO:0034401]; chromatin remodeling [GO:0006338]; chromatin silencing at centromere [GO:0030702]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; CLRC ubiquitin ligase complex localization to heterochromatin [GO:0044382]; filamentous growth [GO:0030447]; filamentous growth of a population of unicellular organisms in response to biotic stimulus [GO:0036180]; filamentous growth of a population of unicellular organisms in response to starvation [GO:0036170]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of histone exchange [GO:1900050]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus [GO:1900445]; positive regulation of filamentous growth of a population of unicellular organisms in response to starvation [GO:1900436]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; regulation of extent of heterochromatin assembly [GO:0031454]; regulation of histone H3-K36 methylation [GO:0000414]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of nucleosome density [GO:0060303]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; transcription elongation from RNA polymerase II promoter [GO:0006368] comp144354_c0_seq1,4135,49.4317,0.53910171,0,8,,2.00E-12,Q9NRA8,Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1),Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1),GO:0016605; GO:0005737; GO:0005829; GO:0016607; GO:0005634; GO:0008565,PML body; cytoplasm; cytosol; nuclear speck; nucleus; protein transporter activity,PF10477;,,,,,,,,,4ET_HUMAN,Homo sapiens (Human),negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; stem cell population maintenance [GO:0019827] comp144354_c0_seq2,5130,47.8558,0.52164061,0,26,,2.00E-10,Q9NRA8,Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1),Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1),GO:0016605; GO:0005737; GO:0005829; GO:0016607; GO:0005634; GO:0008565,PML body; cytoplasm; cytosol; nuclear speck; nucleus; protein transporter activity,PF10477;,5.00E-35,CHOYP_LOC100367084.10.22,,,,,,,4ET_HUMAN,Homo sapiens (Human),negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; stem cell population maintenance [GO:0019827] comp144354_c0_seq3,5353,48.4962,0.53538632,22,27,,,,,,,,,5.00E-35,CHOYP_LOC100367084.10.22,7.00E-12,ruditapes2_c2365,,,,,,, comp144355_c0_seq1,5683,41.369,0.68789226,1497,1375,,2.00E-67,Q8BWW4,La-related protein 4 (La ribonucleoprotein domain family member 4),La-related protein 4 (La ribonucleoprotein domain family member 4),GO:0003723; GO:0007010; GO:0022604,RNA binding; cytoskeleton organization; regulation of cell morphogenesis,PF05383;,8.00E-77,CHOYP_LARP4.1.1,,,,,,,LARP4_MOUSE,Mus musculus (Mouse),cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] comp144357_c1_seq2,730,35.6164,0.64916349,0,0,,3.00E-08,Q71RR4,Snaclec coagulation factor IX/factor X-binding protein subunit A (IX/X-bp subunit A),Snaclec coagulation factor IX/factor X-binding protein subunit A (IX/X-bp subunit A),GO:0030246; GO:0005576; GO:0046872,carbohydrate binding; extracellular region; metal ion binding,PF00059;,,,,,,,,,IXXA_TRIST,Trimeresurus stejnegeri (Chinese green tree viper) (Viridovipera stejnegeri), comp144357_c1_seq4,1161,35.6589,0.76388196,39,487,,2.00E-08,P49300,C-type lectin domain family 10 member A (MMGL) (Macrophage asialoglycoprotein-binding protein 1) (M-ASGP-BP-1) (Macrophage galactose/N-acetylgalactosamine-specific lectin),C-type lectin domain family 10 member A (MMGL) (Macrophage asialoglycoprotein-binding protein 1) (M-ASGP-BP-1) (Macrophage galactose/N-acetylgalactosamine-specific lectin),GO:0030246; GO:0016021,carbohydrate binding; integral to membrane,PF00059;PF03954;,,,,,,,,,CLC10_MOUSE,Mus musculus (Mouse),connective tissue replacement involved in inflammatory response wound healing [GO:0002248] comp144358_c0_seq1,1132,34.5406,0.62370291,11686,211270,,,,,,,,,,,6.00E-11,ruditapes_lrc29311,,,,,,, comp144362_c0_seq1,2138,36.8101,0.52900071,41,233,,4.00E-97,Q767L0,ATP-binding cassette sub-family F member 1,ATP-binding cassette sub-family F member 1,GO:0005524; GO:0006200; GO:0016887; GO:0005635; GO:0005654; GO:0042788; GO:0043022; GO:0008494; GO:0006413,ATP binding; ATP catabolic process; ATPase activity; nuclear envelope; nucleoplasm; polysomal ribosome; ribosome binding; translation activator activity; translational initiation,PF00005;PF12848;,,,,,,,,,ABCF1_PIG,Sus scrofa (Pig),positive regulation of translation [GO:0045727]; translational initiation [GO:0006413] comp144362_c0_seq2,2167,36.9635,0.51723413,6,50,,7.00E-24,P45127,Uncharacterized ABC transporter ATP-binding protein HI_1252,Energy-dependent translational throttle protein EttA (Translational regulatory factor EttA),GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;PF12848;,,,,,,,,,Y1252_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),regulation of translation [GO:0006417]; translation [GO:0006412] comp144362_c0_seq3,2149,36.7148,0.54292941,10,102,,3.00E-56,P40024,ABC transporter ATP-binding protein ARB1 (ATP-binding cassette protein involved in ribosome biogenesis 1),ABC transporter ATP-binding protein ARB1 (ATP-binding cassette protein involved in ribosome biogenesis 1),GO:0005524; GO:0042624; GO:0005737; GO:0005634; GO:0000056,"ATP binding; ATPase activity, uncoupled; cytoplasm; nucleus; ribosomal small subunit export from nucleus",PF00005;PF12848;,,,,,,,,,ARB1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),ribosomal small subunit export from nucleus [GO:0000056]; ribosome biogenesis [GO:0042254] comp144362_c0_seq4,2178,36.8687,0.53064715,0,0,,1.00E-47,P43535,Protein GCN20,Protein GCN20 (General control non-derepressible protein 20),GO:0005524; GO:0016887; GO:0022626; GO:0006448,ATP binding; ATPase activity; cytosolic ribosome; regulation of translational elongation,PF00005;PF12848;,,,,,,,,,GCN20_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to histidine [GO:0071232]; positive regulation of phosphorylation [GO:0042327]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of translational elongation [GO:0006448] comp144362_c0_seq5,1461,43.258,0.44275292,207,983,,7.00E-123,Q7YR37,ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50),ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50),GO:0005524; GO:0006200; GO:0016887; GO:0005635; GO:0005654; GO:0042788; GO:0043022; GO:0008494; GO:0006413,ATP binding; ATP catabolic process; ATPase activity; nuclear envelope; nucleoplasm; polysomal ribosome; ribosome binding; translation activator activity; translational initiation,PF00005;PF12848;,6.00E-135,CHOYP_LOC100863242.1.1,,,,,,,ABCF1_PANTR,Pan troglodytes (Chimpanzee),positive regulation of translation [GO:0045727]; translational initiation [GO:0006413] comp144364_c0_seq1,4046,33.91,0.4216163,1680,4624,,3.00E-13,Q9CQ18,Ribonuclease H2 subunit C (RNase H2 subunit C) (Ribonuclease HI subunit C),Ribonuclease H2 subunit C (RNase H2 subunit C) (Ribonuclease HI subunit C),GO:0006401; GO:0005634; GO:0032299,RNA catabolic process; nucleus; ribonuclease H2 complex,PF08615;,,,,,,,,,RNH2C_MOUSE,Mus musculus (Mouse),RNA catabolic process [GO:0006401] comp144365_c0_seq1,2503,41.5901,0.42636927,13,3,,3.00E-24,Q9PT60,RalA-binding protein 1-A (RalBP1-A) (Ral-interacting protein 1-A) (RIP1-A) (XRLIP2) (XRLIP76-A),RalA-binding protein 1-A (RalBP1-A) (Ral-interacting protein 1-A) (RIP1-A) (XRLIP2) (XRLIP76-A),GO:0005096; GO:0030036; GO:0005829; GO:0001702; GO:0016020; GO:0005886; GO:0043547; GO:0007264,GTPase activator activity; actin cytoskeleton organization; cytosol; gastrulation with mouth forming second; membrane; plasma membrane; positive regulation of GTPase activity; small GTPase mediated signal transduction,PF00620;,,,,,,,,,RBP1A_XENLA,Xenopus laevis (African clawed frog),actin cytoskeleton organization [GO:0030036]; gastrulation with mouth forming second [GO:0001702]; small GTPase mediated signal transduction [GO:0007264] comp144365_c0_seq4,2249,40.996,0.44065814,0,0,,,,,,,,,2.00E-43,CHOYP_RBP1A.1.1,,,,,,,,, comp144365_c1_seq2,720,41.1111,0.50708087,0,21,,2.00E-53,Q15311,RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1),RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1),GO:0043492; GO:0030675; GO:0006935; GO:0005829; GO:0016020; GO:0043089; GO:0007264; GO:0006810,"ATPase activity, coupled to movement of substances; Rac GTPase activator activity; chemotaxis; cytosol; membrane; positive regulation of Cdc42 GTPase activity; small GTPase mediated signal transduction; transport",PF00620;,4.00E-57,CHOYP_RBP1A.1.1,,,,,,,RBP1_HUMAN,Homo sapiens (Human),chemotaxis [GO:0006935]; endocytosis [GO:0006897]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp144368_c1_seq1,3610,42.4654,0.47695238,350,16,,0,Q5ZKD7,Putative helicase MOV-10 (EC 3.6.4.13),Putative helicase MOV-10 (EC 3.6.4.13),GO:0005524; GO:0003723; GO:0000932; GO:0004386; GO:0035279,ATP binding; RNA binding; cytoplasmic mRNA processing body; helicase activity; mRNA cleavage involved in gene silencing by miRNA,,5.00E-52,CHOYP_BRAFLDRAFT_119350.1.1,,,,,,,MOV10_CHICK,Gallus gallus (Chicken),gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279] comp144368_c1_seq3,1802,43.1743,0.43072159,34,0,,1.00E-145,Q5ZKD7,Putative helicase MOV-10 (EC 3.6.4.13),Putative helicase MOV-10 (EC 3.6.4.13),GO:0005524; GO:0003723; GO:0000932; GO:0004386; GO:0035279,ATP binding; RNA binding; cytoplasmic mRNA processing body; helicase activity; mRNA cleavage involved in gene silencing by miRNA,,,,,,,,,,MOV10_CHICK,Gallus gallus (Chicken),gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279] comp144368_c1_seq8,960,42.3958,0.2807892,30,2,,5.00E-56,Q99MV5,Putative helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1),RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog),GO:0005524; GO:0008283; GO:0005737; GO:0004386; GO:0007517; GO:0045786; GO:0007283,ATP binding; cell proliferation; cytoplasm; helicase activity; muscle organ development; negative regulation of cell cycle; spermatogenesis,,3.00E-29,CHOYP_BRAFLDRAFT_119350.1.1,,,,,,,M10L1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp144369_c0_seq1,1183,47.7599,0.47805823,322,264,,5.00E-19,Q9R9N4,Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1),Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1),GO:0006086; GO:0006096; GO:0004739,acetyl-CoA biosynthetic process from pyruvate; glycolysis; pyruvate dehydrogenase (acetyl-transferring) activity,PF00364;PF02779;PF02780;,1.00E-47,CHOYP_RS23.8.9,,,,,,,ODPB_RHIME,Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti),glycolytic process [GO:0006096] comp144369_c0_seq2,2324,34.4234,0.35302163,69,200,,6.00E-58,P86197,"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) (Fragments)","Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) (Fragments)",GO:0004742; GO:0006006; GO:0005759; GO:0006099,dihydrolipoyllysine-residue acetyltransferase activity; glucose metabolic process; mitochondrial matrix; tricarboxylic acid cycle,PF00198;,,,,,,,,,ODP2_MESAU,Mesocricetus auratus (Golden hamster),glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] comp144369_c0_seq3,2312,34.2993,0.35646318,56,112,,1.00E-54,P86197,"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) (Fragments)","Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) (Fragments)",GO:0004742; GO:0006006; GO:0005759; GO:0006099,dihydrolipoyllysine-residue acetyltransferase activity; glucose metabolic process; mitochondrial matrix; tricarboxylic acid cycle,PF00198;,4.00E-57,CHOYP_DLAT.1.1,,,,,,,ODP2_MESAU,Mesocricetus auratus (Golden hamster),glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] comp144374_c0_seq1,1259,39.4758,0.73462295,384,1325,,6.00E-43,Q9CZP0,Ufm1-specific protease 1 (UfSP1) (EC 3.4.22.-),Ufm1-specific protease 1 (UfSP1) (EC 3.4.22.-),GO:0071567; GO:0006508; GO:0016790,UFM1 hydrolase activity; proteolysis; thiolester hydrolase activity,PF07910;,,,,,,,,,UFSP1_MOUSE,Mus musculus (Mouse), comp144374_c1_seq2,1631,45.4936,0.31445798,116,47,,,,,,,,,0,CHOYP_LOC100368525.1.1,,,,,,,,, comp144374_c1_seq3,2932,44.3724,0.37160312,239,74,,0,Q3UGF1,WD repeat-containing protein 19,WD repeat-containing protein 19,GO:0060830; GO:0042384; GO:0005737; GO:0055123; GO:0042471; GO:0031076; GO:0048701; GO:0030326; GO:0001701; GO:0035721; GO:0030991; GO:0005932; GO:0031514; GO:0061055; GO:0050877; GO:0032391; GO:0060831,ciliary receptor clustering involved in smoothened signaling pathway; cilium assembly; cytoplasm; digestive system development; ear morphogenesis; embryonic camera-type eye development; embryonic cranial skeleton morphogenesis; embryonic limb morphogenesis; in utero embryonic development; intraflagellar retrograde transport; intraflagellar transport particle A; microtubule basal body; motile cilium; myotome development; neurological system process; photoreceptor connecting cilium; smoothened signaling pathway involved in dorsal/ventral neural tube patterning,,,,,,,,,,WDR19_MOUSE,Mus musculus (Mouse),cell morphogenesis [GO:0000902]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; digestive system development [GO:0055123]; ear morphogenesis [GO:0042471]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; gonad development [GO:0008406]; intraciliary retrograde transport [GO:0035721]; in utero embryonic development [GO:0001701]; myotome development [GO:0061055]; neurological system process [GO:0050877]; protein localization to cilium [GO:0061512]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] comp144374_c1_seq4,1143,46.3692,0.31533921,0,0,,,,,,,,,0,CHOYP_LOC100368525.1.1,,,,,,,,, comp144377_c0_seq2,1257,34.9244,0.50343349,849,5133,,8.00E-58,P54357,Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain),Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain),GO:0030048; GO:0005509; GO:0016460; GO:0031475; GO:0031476; GO:0031477,actin filament-based movement; calcium ion binding; myosin II complex; myosin V complex; myosin VI complex; myosin VII complex,PF13405;PF13499;,,,1.00E-70,ruditapes_c7414,,,,,MLC2_DROME,Drosophila melanogaster (Fruit fly),actin filament-based movement [GO:0030048] comp144379_c0_seq1,2400,37.5,0.34508929,73,234,,2.00E-54,Q3YBR2,Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2),Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2),GO:0006260; GO:0007050; GO:0008285; GO:0032066; GO:0005634; GO:0050821,DNA replication; cell cycle arrest; negative regulation of cell proliferation; nucleolus to nucleoplasm transport; nucleus; protein stabilization,PF05965;PF05964;,,,,,,,,,TBRG1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; DNA replication [GO:0006260]; negative regulation of cell proliferation [GO:0008285]; nucleolus to nucleoplasm transport [GO:0032066]; protein stabilization [GO:0050821] comp144379_c0_seq4,2303,37.8202,0.35323605,73,464,,2.00E-54,Q3YBR2,Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2),Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2),GO:0006260; GO:0007050; GO:0008285; GO:0032066; GO:0005634; GO:0050821,DNA replication; cell cycle arrest; negative regulation of cell proliferation; nucleolus to nucleoplasm transport; nucleus; protein stabilization,PF05965;PF05964;,,,,,,,,,TBRG1_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; DNA replication [GO:0006260]; negative regulation of cell proliferation [GO:0008285]; nucleolus to nucleoplasm transport [GO:0032066]; protein stabilization [GO:0050821] comp144381_c0_seq1,1832,43.3406,0.49766973,0,7,,0,C4V922,Probable DNA repair helicase RAD25 homolog (EC 3.6.4.12) (General transcription and DNA repair factor IIH subunit RAD25) (TFIIH subunit RAD25),Probable DNA repair helicase RAD25 homolog (EC 3.6.4.12) (General transcription and DNA repair factor IIH subunit RAD25) (TFIIH subunit RAD25),GO:0005524; GO:0004003; GO:0003677; GO:0006289; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent DNA helicase activity; DNA binding; nucleotide-excision repair; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16203;PF13625;PF04851;,2.00E-53,CHOYP_LOC100639240.1.1,,,,,,,RAD25_NOSCE,Nosema ceranae (strain BRL01) (Microsporidian parasite),"nucleotide-excision repair, DNA incision [GO:0033683]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; poly(A)+ mRNA export from nucleus [GO:0016973]; promoter clearance from RNA polymerase II promoter [GO:0001111]; regulation of mitotic recombination [GO:0000019]; regulation of transposition, RNA-mediated [GO:0010525]; transcriptional open complex formation at RNA polymerase II promoter [GO:0001113]" comp144381_c0_seq2,3026,42.4653,0.52189661,40,144,,0,Q60HG1,TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3),TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3),GO:0043138; GO:0005524; GO:0004003; GO:0016887; GO:0003677; GO:0006265; GO:0006915; GO:0035315; GO:0005675; GO:0000717; GO:0033683; GO:0045944; GO:0008022; GO:0047485; GO:0008104; GO:0006468; GO:1901990; GO:0009411; GO:0006979; GO:0006366; GO:0006283,"3'-5' DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; ATPase activity; DNA binding; DNA topological change; apoptotic process; hair cell differentiation; holo TFIIH complex; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; positive regulation of transcription from RNA polymerase II promoter; protein C-terminus binding; protein N-terminus binding; protein localization; protein phosphorylation; regulation of mitotic cell cycle phase transition; response to UV; response to oxidative stress; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF16203;PF13625;PF04851;,,,,,,,,,ERCC3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp144381_c0_seq5,3044,42.3127,0.51515647,7,109,,0,Q1RMT1,TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3),TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3),GO:0043138; GO:0005524; GO:0004003; GO:0016887; GO:0003677; GO:0006265; GO:0008353; GO:0009650; GO:0006915; GO:0000075; GO:0035315; GO:0005675; GO:0000717; GO:0033683; GO:0045944; GO:0008022; GO:0047485; GO:0008104; GO:0006468; GO:1901990; GO:0009411; GO:0006979; GO:0006366; GO:0006283,"3'-5' DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; ATPase activity; DNA binding; DNA topological change; RNA polymerase II carboxy-terminal domain kinase activity; UV protection; apoptotic process; cell cycle checkpoint; hair cell differentiation; holo TFIIH complex; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; positive regulation of transcription from RNA polymerase II promoter; protein C-terminus binding; protein N-terminus binding; protein localization; protein phosphorylation; regulation of mitotic cell cycle phase transition; response to UV; response to oxidative stress; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF16203;PF13625;PF04851;,0,CHOYP_ERCC3.1.1,,,,,,,ERCC3_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; UV protection [GO:0009650]" comp144381_c0_seq6,1639,43.6242,0.50905753,0,3,,0,Q1RMT1,TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3),TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3),GO:0043138; GO:0005524; GO:0004003; GO:0016887; GO:0003677; GO:0006265; GO:0008353; GO:0009650; GO:0006915; GO:0000075; GO:0035315; GO:0005675; GO:0000717; GO:0033683; GO:0045944; GO:0008022; GO:0047485; GO:0008104; GO:0006468; GO:1901990; GO:0009411; GO:0006979; GO:0006366; GO:0006283,"3'-5' DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; ATPase activity; DNA binding; DNA topological change; RNA polymerase II carboxy-terminal domain kinase activity; UV protection; apoptotic process; cell cycle checkpoint; hair cell differentiation; holo TFIIH complex; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; positive regulation of transcription from RNA polymerase II promoter; protein C-terminus binding; protein N-terminus binding; protein localization; protein phosphorylation; regulation of mitotic cell cycle phase transition; response to UV; response to oxidative stress; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF16203;PF13625;PF04851;,0,CHOYP_ERCC3.1.1,,,,,,,ERCC3_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; UV protection [GO:0009650]" comp144382_c0_seq2,3864,40.9938,0.63526152,415,712,,0,Q9NRZ9,Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6),Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6),GO:0005524; GO:0003677; GO:0051301; GO:0005721; GO:0031508; GO:0003682; GO:0004386; GO:0046651; GO:0010216; GO:0006346; GO:0007067; GO:0007275; GO:0043066; GO:0005634; GO:0006351; GO:0001655,"ATP binding; DNA binding; cell division; centromeric heterochromatin; centromeric heterochromatin assembly; chromatin binding; helicase activity; lymphocyte proliferation; maintenance of DNA methylation; methylation-dependent chromatin silencing; mitosis; multicellular organismal development; negative regulation of apoptotic process; nucleus; transcription, DNA-dependent; urogenital system development",PF00271;PF00176;,1.00E-72,CHOYP_HELLS.1.1,,,,,,,HELLS_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; lymphocyte proliferation [GO:0046651]; maintenance of DNA methylation [GO:0010216]; methylation-dependent chromatin silencing [GO:0006346]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]; pericentric heterochromatin assembly [GO:0031508]; transcription, DNA-templated [GO:0006351]" comp144383_c0_seq1,3090,35.8252,1.01994362,143,709,,9.00E-56,P18173,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660; GO:0004344; GO:0006006; GO:0008364; GO:0046693,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding; glucose dehydrogenase activity; glucose metabolic process; pupal chitin-based cuticle development; sperm storage,PF05199;PF00732;,8.00E-17,CHOYP_LOC100877446.2.2,,,,,,,DHGL_DROME,Drosophila melanogaster (Fruit fly),cuticle development [GO:0042335]; glucose metabolic process [GO:0006006]; pupal chitin-based cuticle development [GO:0008364]; sensory perception of pain [GO:0019233]; sperm storage [GO:0046693] comp144383_c0_seq3,2088,39.4636,0.95105302,27,82,,5.00E-59,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,2.00E-16,CHOYP_LOC100646609.1.1,7.00E-20,ruditapes_c10345,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp144384_c0_seq3,1436,38.7883,0.37088675,80,58,,1.00E-77,Q6AXS8,Tubulin polyglutamylase complex subunit 2 (PGs2),Tubulin polyglutamylase complex subunit 2 (PGs2),GO:0005737; GO:0005874,cytoplasm; microtubule,,6.00E-72,CHOYP_LOC100370327.1.1,,,,,,,TPGS2_RAT,Rattus norvegicus (Rat), comp144385_c0_seq3,1938,40.0929,0.27086057,119,1128,,3.00E-06,Q6E2N3,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TRI33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp144386_c0_seq1,1446,35.6155,0.68887864,0,0,,4.00E-35,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,6.00E-21,CHOYP_LOC100892567.3.8,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144386_c0_seq5,1473,35.0984,0.71583837,0,0,,4.00E-42,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144386_c0_seq8,612,33.1699,0.77444327,0,0,,3.00E-12,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,1.00E-18,CHOYP_LOC100892567.3.8,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp144386_c0_seq9,585,34.359,0.69623966,0,0,,,,,,,,,1.00E-11,CHOYP_RTJK.3.3,,,,,,,,, comp144387_c1_seq2,2402,42.423,0.46304155,0,0,,2.00E-69,Q93075,Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),GO:0006987; GO:0044267; GO:0016888; GO:0046872; GO:0090305; GO:0005654,"activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleoplasm",PF01026;,2.00E-36,CHOYP_LOC578076.1.1,,,,,,,TATD2_HUMAN,Homo sapiens (Human),DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498] comp144387_c1_seq4,2626,41.6984,0.45603687,20,18,,5.00E-69,Q93075,Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),GO:0006987; GO:0044267; GO:0016888; GO:0046872; GO:0090305; GO:0005654,"activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleoplasm",PF01026;,2.00E-36,CHOYP_LOC578076.1.1,,,,,,,TATD2_HUMAN,Homo sapiens (Human),DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498] comp144387_c1_seq8,2250,42.7556,0.47690687,0,0,,6.00E-24,P37545,Uncharacterized deoxyribonuclease YabD (EC 3.1.21.-),Uncharacterized metal-dependent hydrolase YabD (EC 3.1.-.-),GO:0016888; GO:0046872; GO:0090305,"endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis",PF01026;,,,,,,,,,YABD_BACSU,Bacillus subtilis (strain 168),DNA catabolic process [GO:0006308] comp144387_c1_seq9,2250,42.6667,0.45952552,0,0,,1.00E-69,Q93075,Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),Putative deoxyribonuclease TATDN2 (EC 3.1.21.-),GO:0006987; GO:0044267; GO:0016888; GO:0046872; GO:0090305; GO:0005654,"activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleoplasm",PF01026;,2.00E-36,CHOYP_LOC578076.1.1,,,,,,,TATD2_HUMAN,Homo sapiens (Human),DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498] comp144388_c0_seq1,3895,46.0077,0.46169202,13,7,,6.00E-58,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,5.00E-90,CHOYP_BRAFLDRAFT_125670.1.1,,,,,,,CL063_HUMAN,, comp144388_c0_seq3,3916,45.9908,0.46440334,46,0,,6.00E-57,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp144388_c0_seq4,2278,43.8543,0.53023397,15,15,,,,,,,,,,,3.00E-44,ruditapes2_c3380,,,,,,, comp144388_c0_seq5,3630,46.1433,0.46694562,1,11,,,,,,,,,5.00E-90,CHOYP_BRAFLDRAFT_125670.1.1,,,,,,,,, comp144388_c0_seq6,3651,46.0148,0.47211686,54,0,,6.00E-51,Q6ZTY8,Putative uncharacterized protein C12orf63,,,,,,,,,,,,,CL063_HUMAN,, comp144388_c0_seq7,245,45.3061,0.20247251,0,0,,,,,,,,,9.00E-35,CHOYP_LOC575277.2.2,,,,,,,,, comp144389_c0_seq1,1932,29.5031,0.96120163,23,2252,female>male,,,,,,,,,,5.00E-15,ruditapes_c18233,,,,,,, comp144390_c1_seq1,3549,42.2936,0.51984095,457,1524,,0,Q17R09,Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38),Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38),GO:0005524; GO:0008026; GO:0008380; GO:0006397; GO:0003676; GO:0005681,ATP binding; ATP-dependent helicase activity; RNA splicing; mRNA processing; nucleic acid binding; spliceosomal complex,PF00270;PF04408;PF00271;PF07717;,0,CHOYP_PRP16.1.1,,,,,,,PRP16_BOVIN,Bos taurus (Bovine),"mRNA splicing, via spliceosome [GO:0000398]" comp144391_c0_seq1,6631,40.1749,0.82625999,475,0,,1.00E-27,Q76MJ5,Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0030263; GO:0007050; GO:0004519; GO:0005789; GO:0016021; GO:0006397; GO:0000287; GO:0045892; GO:0004674; GO:0016075; GO:0006950; GO:0004540; GO:0006351,"ATP binding; apoptotic chromosome condensation; cell cycle arrest; endonuclease activity; endoplasmic reticulum membrane; integral to membrane; mRNA processing; magnesium ion binding; negative regulation of transcription, DNA-dependent; protein serine/threonine kinase activity; rRNA catabolic process; response to stress; ribonuclease activity; transcription, DNA-dependent",PF00069;PF06479;,,,,,,,,,ERN2_HUMAN,Homo sapiens (Human),"apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]" comp144391_c0_seq2,6356,40.7646,0.81475321,462,0,,2.00E-27,Q76MJ5,Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0030263; GO:0007050; GO:0004519; GO:0005789; GO:0016021; GO:0006397; GO:0000287; GO:0045892; GO:0004674; GO:0016075; GO:0006950; GO:0004540; GO:0006351,"ATP binding; apoptotic chromosome condensation; cell cycle arrest; endonuclease activity; endoplasmic reticulum membrane; integral to membrane; mRNA processing; magnesium ion binding; negative regulation of transcription, DNA-dependent; protein serine/threonine kinase activity; rRNA catabolic process; response to stress; ribonuclease activity; transcription, DNA-dependent",PF00069;PF06479;,1.00E-12,CHOYP_PHUM_PHUM319520.1.1,,,,,,,ERN2_HUMAN,Homo sapiens (Human),"apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]" comp144392_c0_seq2,2235,33.1544,0.31252489,274,1914,,1.00E-16,Q8AVK1,Mitochondrial import inner membrane translocase subunit Tim13-B,Mitochondrial import inner membrane translocase subunit Tim13-B,GO:0046872; GO:0005743; GO:0015031,metal ion binding; mitochondrial inner membrane; protein transport,PF02953;,,,7.00E-33,ruditapes_c7200,,,,,TI13B_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp144393_c0_seq1,1755,43.7607,0.9375786,3479,13513,,2.00E-06,Q9UPN9,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0030514; GO:0000122; GO:0005654; GO:0017015; GO:0006367; GO:0007179; GO:0004842; GO:0008270,DNA binding; negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; regulation of transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_HUMAN,Homo sapiens (Human),"negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]" comp144394_c0_seq1,2894,45.1279,0.62925019,76,35,,0,Q61371,Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw),Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw),GO:0009952; GO:0045177; GO:0060411; GO:0005814; GO:0035085; GO:0036064; GO:0060271; GO:0007368; GO:0042733; GO:0048568; GO:0003382; GO:0001654; GO:0048853; GO:0001701; GO:0060426; GO:0031512; GO:0060021; GO:0032391; GO:0045862; GO:0008104; GO:0016485; GO:0042487; GO:0007224; GO:0021513; GO:0021537,anterior/posterior pattern specification; apical part of cell; cardiac septum morphogenesis; centriole; cilium axoneme; cilium basal body; cilium morphogenesis; determination of left/right symmetry; embryonic digit morphogenesis; embryonic organ development; epithelial cell morphogenesis; eye development; forebrain morphogenesis; in utero embryonic development; lung vasculature development; motile primary cilium; palate development; photoreceptor connecting cilium; positive regulation of proteolysis; protein localization; protein processing; regulation of odontogenesis of dentin-containing tooth; smoothened signaling pathway; spinal cord dorsal/ventral patterning; telencephalon development,PF13174;PF13181;,0,CHOYP_BRAFLDRAFT_208090.1.1,,,,,,,IFT88_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cochlea development [GO:0090102]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; epidermal stem cell homeostasis [GO:0036334]; epidermis development [GO:0008544]; epithelial cell morphogenesis [GO:0003382]; eye development [GO:0001654]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; heart formation [GO:0060914]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; limb development [GO:0060173]; liver development [GO:0001889]; lung development [GO:0030324]; lung vasculature development [GO:0060426]; negative regulation of epithelial cell proliferation [GO:0050680]; nervous system development [GO:0007399]; neural precursor cell proliferation [GO:0061351]; nonmotile primary cilium assembly [GO:0035058]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; palate development [GO:0060021]; pancreas development [GO:0031016]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; protein localization [GO:0008104]; regulation of autophagosome assembly [GO:2000785]; regulation of cilium assembly [GO:1902017]; regulation of fat cell differentiation [GO:0045598]; regulation of feeding behavior [GO:0060259]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of protein processing [GO:0070613]; regulation of smoothened signaling pathway [GO:0008589]; response to fluid shear stress [GO:0034405]; smoothened signaling pathway [GO:0007224]; spermatid nucleus elongation [GO:0007290]; sperm axoneme assembly [GO:0007288]; spinal cord dorsal/ventral patterning [GO:0021513]; telencephalon development [GO:0021537] comp144394_c0_seq2,1778,42.8009,0.68651617,78,31,,3.00E-07,Q3UV71,Transmembrane and TPR repeat-containing protein 1,Transmembrane and TPR repeat-containing protein 1,GO:0016021; GO:0005739,integral to membrane; mitochondrion,PF08409;PF13414;,,,,,,,,,TMTC1_MOUSE,Mus musculus (Mouse),RNA processing [GO:0006396] comp144394_c0_seq3,2594,45.7594,0.61485793,0,24,,0,Q61371,Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw),Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw),GO:0009952; GO:0045177; GO:0060411; GO:0005814; GO:0035085; GO:0036064; GO:0060271; GO:0007368; GO:0042733; GO:0048568; GO:0003382; GO:0001654; GO:0048853; GO:0001701; GO:0060426; GO:0031512; GO:0060021; GO:0032391; GO:0045862; GO:0008104; GO:0016485; GO:0042487; GO:0007224; GO:0021513; GO:0021537,anterior/posterior pattern specification; apical part of cell; cardiac septum morphogenesis; centriole; cilium axoneme; cilium basal body; cilium morphogenesis; determination of left/right symmetry; embryonic digit morphogenesis; embryonic organ development; epithelial cell morphogenesis; eye development; forebrain morphogenesis; in utero embryonic development; lung vasculature development; motile primary cilium; palate development; photoreceptor connecting cilium; positive regulation of proteolysis; protein localization; protein processing; regulation of odontogenesis of dentin-containing tooth; smoothened signaling pathway; spinal cord dorsal/ventral patterning; telencephalon development,PF13174;PF13181;,0,CHOYP_BRAFLDRAFT_208090.1.1,,,4.00E-66,ES789731.p.cg.6,7,,IFT88_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cochlea development [GO:0090102]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; epidermal stem cell homeostasis [GO:0036334]; epidermis development [GO:0008544]; epithelial cell morphogenesis [GO:0003382]; eye development [GO:0001654]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; heart formation [GO:0060914]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; limb development [GO:0060173]; liver development [GO:0001889]; lung development [GO:0030324]; lung vasculature development [GO:0060426]; negative regulation of epithelial cell proliferation [GO:0050680]; nervous system development [GO:0007399]; neural precursor cell proliferation [GO:0061351]; nonmotile primary cilium assembly [GO:0035058]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; palate development [GO:0060021]; pancreas development [GO:0031016]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; protein localization [GO:0008104]; regulation of autophagosome assembly [GO:2000785]; regulation of cilium assembly [GO:1902017]; regulation of fat cell differentiation [GO:0045598]; regulation of feeding behavior [GO:0060259]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of protein processing [GO:0070613]; regulation of smoothened signaling pathway [GO:0008589]; response to fluid shear stress [GO:0034405]; smoothened signaling pathway [GO:0007224]; spermatid nucleus elongation [GO:0007290]; sperm axoneme assembly [GO:0007288]; spinal cord dorsal/ventral patterning [GO:0021513]; telencephalon development [GO:0021537] comp144394_c0_seq4,1743,43.0866,0.66575455,0,0,,3.00E-07,Q3UV71,Transmembrane and TPR repeat-containing protein 1,Transmembrane and TPR repeat-containing protein 1,GO:0016021; GO:0005739,integral to membrane; mitochondrion,PF08409;PF13414;,,,,,,,,,TMTC1_MOUSE,Mus musculus (Mouse),RNA processing [GO:0006396] comp144394_c0_seq5,1201,44.6295,0.68036499,49,31,,3.00E-06,P19737,TPR repeat-containing protein SYNPCC7002_A0425,TPR repeat-containing protein SYNPCC7002_A0425,,,PF13414;PF13174;,,,,,,,,,Y425_SYNP2,Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum), comp144395_c0_seq1,2691,42.252,0.32619156,31,0,,,,,,,,,1.00E-44,CHOYP_CT194.1.1,,,,,,,,, comp144395_c0_seq2,5305,40.1508,0.32901172,3,0,,0,Q5TEA3,Uncharacterized protein C20orf194,Uncharacterized protein C20orf194,,,,,,9.00E-11,ruditapes_c7836,,,,,CT194_HUMAN,Homo sapiens (Human), comp144395_c0_seq3,5344,40.1946,0.32583177,14,8,,0,Q5TEA3,Uncharacterized protein C20orf194,Uncharacterized protein C20orf194,,,,3.00E-44,CHOYP_CT194.1.1,,,,,,,CT194_HUMAN,Homo sapiens (Human), comp144395_c0_seq4,583,38.9365,0.36868795,2,0,,,,,,,,,3.00E-45,CHOYP_CT194.1.1,,,,,,,,, comp144396_c0_seq1,3527,42.7275,0.42556546,370,1157,,4.00E-93,Q5TYP4,Uncharacterized protein C1orf112 homolog,Uncharacterized protein C1orf112 homolog,,,PF14868;,,,,,,,,,CA112_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144397_c0_seq1,6158,39.7532,0.48626635,0,0,,,,,,,,,2.00E-47,CHOYP_CRE-FBN-1.2.2,,,,,,,,, comp144397_c0_seq3,8052,38.1644,0.52678926,6,6,,,,,,,,,2.00E-47,CHOYP_CRE-FBN-1.2.2,1.00E-11,ruditapes2_c2054,,,,,,, comp144397_c0_seq5,6043,39.583,0.49106824,0,0,,,,,,,,,2.00E-47,CHOYP_CRE-FBN-1.2.2,,,,,,,,, comp144397_c0_seq6,6077,39.5096,0.49014631,0,0,,,,,,,,,2.00E-47,CHOYP_CRE-FBN-1.2.2,,,,,,,,, comp144398_c0_seq2,3919,37.1013,0.47924693,3,7,,8.00E-129,Q6DG03,Cyclin-D-binding Myb-like transcription factor 1,Cyclin-D-binding Myb-like transcription factor 1,GO:0003677; GO:0007049; GO:0003682; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell cycle; chromatin binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00249;,9.00E-100,CHOYP_DMTF1.1.2,,,,,,,DMTF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144399_c0_seq3,1601,40.9119,0.43012502,52,134,,2.00E-121,Q5RC70,DnaJ homolog subfamily C member 11,DnaJ homolog subfamily C member 11,,,PF00226;PF11875;,,,,,,,,,DJC11_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp144399_c0_seq6,1600,40.9375,0.41538877,31,57,,2.00E-13,C5B7L8,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,1.00E-18,CHOYP_DNAJC11.1.1,,,,,,,DNAJ_EDWI9,Edwardsiella ictaluri (strain 93-146),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp144400_c0_seq1,3287,39.2455,0.57886055,684,3477,,1.00E-46,Q75M08,Protein disulfide isomerase-like 2-1 (OsPDIL2-1) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-1) (OsPDIL4-1),Protein disulfide isomerase-like 2-1 (OsPDIL2-1) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-1) (OsPDIL4-1),GO:0045454; GO:0005783; GO:0005576; GO:0006662; GO:0003756; GO:0015035; GO:0006457,cell redox homeostasis; endoplasmic reticulum; extracellular region; glycerol ether metabolic process; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding,PF07749;PF00085;,,,,,,,,,PDI21_ORYSJ,Oryza sativa subsp. japonica (Rice),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp144400_c0_seq2,3138,38.6233,0.55700013,72,636,,4.00E-180,Q63081,Protein disulfide-isomerase A6 (EC 5.3.4.1) (Calcium-binding protein 1) (CaBP1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7),Protein disulfide-isomerase A6 (EC 5.3.4.1) (Calcium-binding protein 1) (CaBP1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7),GO:0005509; GO:0045454; GO:0005788; GO:0005793; GO:0006662; GO:0042470; GO:0005886; GO:0070527; GO:0003756; GO:0015035; GO:0005790,calcium ion binding; cell redox homeostasis; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; glycerol ether metabolic process; melanosome; plasma membrane; platelet aggregation; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; smooth endoplasmic reticulum,PF00085;,2.00E-108,CHOYP_PDIA6.1.2,,,,,,,PDIA6_RAT,Rattus norvegicus (Rat),apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp144401_c0_seq1,7370,45.5495,0.3954447,46,7,,0,Q7Z6Z7,"E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)","E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)",GO:0003677; GO:0006284; GO:0030154; GO:0005737; GO:0016574; GO:0005634; GO:0006513; GO:0000209; GO:0042787; GO:0004842,DNA binding; base-excision repair; cell differentiation; cytoplasm; histone ubiquitination; nucleus; protein monoubiquitination; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;,,,,,,,,,HUWE1_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144401_c0_seq2,7338,45.5846,0.39389139,19,0,,3.00E-10,Q03280,E3 ubiquitin-protein ligase TOM1 (EC 6.3.2.-) (Suppressor of snRNA protein 2) (Temperature-dependent organization in mitotic nucleus protein 1),E3 ubiquitin-protein ligase TOM1 (EC 6.3.2.-) (Suppressor of snRNA protein 2) (Temperature-dependent organization in mitotic nucleus protein 1),GO:0000448; GO:0000480; GO:0000447; GO:0000472; GO:0051028; GO:0007067; GO:0006913; GO:0005730; GO:0006997; GO:0042787; GO:0006355; GO:0006351; GO:0004842,"cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mRNA transport; mitosis; nucleocytoplasmic transport; nucleolus; nucleus organization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin-protein ligase activity",PF14377;PF06012;PF06025;PF00632;,0,CHOYP_HUWE1.2.2,,,,,,,TOM1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; nucleus organization [GO:0006997]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144401_c0_seq4,1430,41.6783,0.41897254,7,12,,0,Q7TMY8,"E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)","E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)",GO:0003677; GO:0006284; GO:0030154; GO:0005737; GO:0016574; GO:0005634; GO:0006513; GO:0000209; GO:0042787; GO:0004842,DNA binding; base-excision repair; cell differentiation; cytoplasm; histone ubiquitination; nucleus; protein monoubiquitination; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;,0,CHOYP_HUWE1.2.2,,,,,,,HUWE1_MOUSE,Mus musculus (Mouse),base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144403_c1_seq1,2843,36.4756,0.38083623,0,0,,1.00E-150,Q16UN6,Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit),Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit),GO:0006370; GO:0000339; GO:0031047; GO:0045292; GO:0051028; GO:0005846; GO:0005634,"7-methylguanosine mRNA capping; RNA cap binding; gene silencing by RNA; mRNA cis splicing, via spliceosome; mRNA transport; nuclear cap binding complex; nucleus",PF02854;PF09088;PF09090;,,,,,,,,,NCBP1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA transport [GO:0051028]" comp144403_c1_seq2,2874,35.9429,0.38807654,1,41,,4.00E-23,Q55D17,Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit),Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit),GO:0006370; GO:0000339; GO:0031047; GO:0045292; GO:0000398; GO:0051028; GO:0005846; GO:0005634,"7-methylguanosine mRNA capping; RNA cap binding; gene silencing by RNA; mRNA cis splicing, via spliceosome; mRNA splicing, via spliceosome; mRNA transport; nuclear cap binding complex; nucleus",PF02854;PF09088;PF09090;,4.00E-172,CHOYP_LOC661829.1.1,,,,,,,NCBP1_DICDI,Dictyostelium discoideum (Slime mold),"7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]" comp144403_c1_seq3,2917,36.3387,0.37397475,59,294,,2.00E-38,Q10LJ0,Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit),Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit),GO:0006370; GO:0000339; GO:0005737; GO:0031047; GO:0045292; GO:0051028; GO:0005846; GO:0005634,"7-methylguanosine mRNA capping; RNA cap binding; cytoplasm; gene silencing by RNA; mRNA cis splicing, via spliceosome; mRNA transport; nuclear cap binding complex; nucleus",PF02854;PF09088;PF09090;,4.00E-172,CHOYP_LOC661829.1.1,,,,,,,NCBP1_ORYSJ,Oryza sativa subsp. japonica (Rice),"7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA transport [GO:0051028]" comp144403_c1_seq4,1172,42.4061,0.55501754,131,379,,1.00E-180,Q6GQ80,Nuclear cap-binding protein subunit 1-A,Nuclear cap-binding protein subunit 1-A,GO:0000339; GO:0045292; GO:0051028; GO:0005846; GO:0005634,"RNA cap binding; mRNA cis splicing, via spliceosome; mRNA transport; nuclear cap binding complex; nucleus",PF02854;PF09088;PF09090;,,,,,,,,,NBP1A_XENLA,Xenopus laevis (African clawed frog),"7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translation [GO:0006417]" comp144404_c0_seq1,1095,36.895,0.72980233,85,440,,4.00E-09,Q99PP7,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0070412; GO:0070410; GO:0016874; GO:0030514; GO:0005634; GO:0016567; GO:0006355; GO:0017015; GO:0006351; GO:0008270,"DNA binding; R-SMAD binding; co-SMAD binding; ligase activity; negative regulation of BMP signaling pathway; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; regulation of transforming growth factor beta receptor signaling pathway; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_MOUSE,Mus musculus (Mouse),"negative regulation of BMP signaling pathway [GO:0030514]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]" comp144405_c0_seq2,2649,33.8618,0.75284102,366,1438,,4.00E-33,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,2.00E-36,CHOYP_LOC100892567.3.8,3.00E-19,ruditapes_c9179,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144407_c0_seq2,3745,46.6222,0.50244143,0,0,,8.00E-36,Q9UPV0,Centrosomal protein of 164 kDa (Cep164),Centrosomal protein of 164 kDa (Cep164),GO:0006281; GO:0000086; GO:0051301; GO:0005814; GO:0005929; GO:0042384; GO:0005829; GO:0007067; GO:0005634,DNA repair; G2/M transition of mitotic cell cycle; cell division; centriole; cilium; cilium assembly; cytosol; mitosis; nucleus,,2.00E-45,CHOYP_CEP164.1.1,,,,,,,CE164_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cilium assembly [GO:0042384]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067] comp144407_c0_seq3,3722,46.5879,0.50077071,0,0,,,,,,,,,2.00E-45,CHOYP_CEP164.1.1,,,,,,,,, comp144407_c0_seq5,3758,46.5673,0.49653263,0,0,,8.00E-36,Q9UPV0,Centrosomal protein of 164 kDa (Cep164),Centrosomal protein of 164 kDa (Cep164),GO:0006281; GO:0000086; GO:0051301; GO:0005814; GO:0005929; GO:0042384; GO:0005829; GO:0007067; GO:0005634,DNA repair; G2/M transition of mitotic cell cycle; cell division; centriole; cilium; cilium assembly; cytosol; mitosis; nucleus,,,,,,,,,,CE164_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cilium assembly [GO:0042384]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067] comp144407_c0_seq9,3709,46.5355,0.49887716,0,0,,7.00E-36,Q9UPV0,Centrosomal protein of 164 kDa (Cep164),Centrosomal protein of 164 kDa (Cep164),GO:0006281; GO:0000086; GO:0051301; GO:0005814; GO:0005929; GO:0042384; GO:0005829; GO:0007067; GO:0005634,DNA repair; G2/M transition of mitotic cell cycle; cell division; centriole; cilium; cilium assembly; cytosol; mitosis; nucleus,,2.00E-45,CHOYP_CEP164.1.1,5.00E-31,ruditapes_c31895,,,,,CE164_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cilium assembly [GO:0042384]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067] comp144408_c0_seq1,2926,43.985,0.43286015,699,639,,0,Q9YHY6,Condensin complex subunit 1 (Chromosome assembly protein XCAP-D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (Eg7) (Non-SMC condensin I complex subunit D2),Condensin complex subunit 1 (Chromosome assembly protein XCAP-D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (Eg7) (Non-SMC condensin I complex subunit D2),GO:0051301; GO:0005694; GO:0005829; GO:0007076; GO:0005634,cell division; chromosome; cytosol; mitotic chromosome condensation; nucleus,PF12717;PF12922;,,,,,,,,,CND1_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp144408_c1_seq2,1463,44.1558,0.64285744,10,19,,4.00E-53,Q06156,Condensin complex subunit 1 (XCAP-D2 homolog),Condensin complex subunit 1 (XCAP-D2 homolog),GO:0051301; GO:0030466; GO:0043007; GO:0010032; GO:0051307; GO:0007076; GO:0000799; GO:0005730; GO:0007130; GO:0070058,cell division; chromatin silencing at silent mating-type cassette; maintenance of rDNA; meiotic chromosome condensation; meiotic chromosome separation; mitotic chromosome condensation; nuclear condensin complex; nucleolus; synaptonemal complex assembly; tRNA gene clustering,PF12717;PF12922;,1.00E-144,CHOYP_BRAFLDRAFT_283981.1.1,,,,,,,CND1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cell division [GO:0051301]; chromatin silencing at silent mating-type cassette [GO:0030466]; maintenance of rDNA [GO:0043007]; meiotic chromosome condensation [GO:0010032]; meiotic chromosome separation [GO:0051307]; mitotic chromosome condensation [GO:0007076]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of meiotic DNA double-strand break formation [GO:1903342]; synaptonemal complex assembly [GO:0007130]; tRNA gene clustering [GO:0070058] comp144408_c1_seq4,1754,42.9304,0.65133629,43,121,,9.00E-07,Q6ZQK0,Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3),Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3),GO:0051301; GO:0042585; GO:0007076; GO:0000799,cell division; germinal vesicle; mitotic chromosome condensation; nuclear condensin complex,PF12717;,2.00E-143,CHOYP_BRAFLDRAFT_283981.1.1,,,,,,,CNDD3_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076] comp144409_c0_seq1,1979,46.6397,0.52098911,45,0,,6.00E-42,P25655,General negative regulator of transcription subunit 1 (Cell division cycle protein 39),General negative regulator of transcription subunit 1 (Cell division cycle protein 39),GO:0030015; GO:0005737; GO:0000289; GO:0005634; GO:0032968; GO:0007124; GO:0051726; GO:0000749; GO:0006368,CCR4-NOT core complex; cytoplasm; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; positive regulation of transcription elongation from RNA polymerase II promoter; pseudohyphal growth; regulation of cell cycle; response to pheromone involved in conjugation with cellular fusion; transcription elongation from RNA polymerase II promoter,PF16415;PF16418;PF16419;PF16417;PF12842;PF04054;,,,,,,,,,NOT1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; pseudohyphal growth [GO:0007124]; regulation of cell cycle [GO:0051726]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to pheromone involved in conjugation with cellular fusion [GO:0000749]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp144409_c0_seq2,5445,47.236,0.49440924,333,263,,0,Q6ZQ08,CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1),CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1),GO:0030014; GO:0000932; GO:0030331; GO:0031047; GO:0033147; GO:0048387; GO:0000122; GO:0005634; GO:0010606; GO:1900153; GO:0060213; GO:2000036; GO:0006417; GO:0042974; GO:0006351; GO:0001829,"CCR4-NOT complex; cytoplasmic mRNA processing body; estrogen receptor binding; gene silencing by RNA; negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of retinoic acid receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of cytoplasmic mRNA processing body assembly; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; regulation of stem cell maintenance; regulation of translation; retinoic acid receptor binding; transcription, DNA-dependent; trophectodermal cell differentiation",PF16415;PF16418;PF16417;PF12842;PF04054;,0,CHOYP_CNOT1.1.1,,,,,,,CNOT1_MOUSE,Mus musculus (Mouse),"gene silencing by miRNA [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]" comp144411_c0_seq3,1500,37.4,0.32518174,130,573,,4.00E-103,Q9R1S0,B9 domain-containing protein 1 (Endothelial precursor cells protein B9),B9 domain-containing protein 1 (Endothelial precursor cells protein B9),GO:0036038; GO:0043010; GO:0035051; GO:0005813; GO:0042384; GO:0005737; GO:0042733; GO:0008158; GO:0001701; GO:0016020; GO:0005932; GO:0060563; GO:0032880; GO:0007224,TCTN-B9D complex; camera-type eye development; cardiocyte differentiation; centrosome; cilium assembly; cytoplasm; embryonic digit morphogenesis; hedgehog receptor activity; in utero embryonic development; membrane; microtubule basal body; neuroepithelial cell differentiation; regulation of protein localization; smoothened signaling pathway,PF07162;,9.00E-89,CHOYP_LOC100561894.1.1,,,5.00E-89,AM859337.p.cg.6,5,,B9D1_MOUSE,Mus musculus (Mouse),camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; in utero embryonic development [GO:0001701]; neuroepithelial cell differentiation [GO:0060563]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]; vasculature development [GO:0001944] comp144412_c1_seq4,303,44.2244,0.67721834,15,165,,,,,,,,,,,1.00E-12,ruditapes_c28149,,,,,,, comp144412_c1_seq5,459,38.9978,0.80520512,11,388,,,,,,,,,,,9.00E-11,ruditapes_c10156,,,,,,, comp144413_c0_seq2,1734,35.7555,0.57968613,622,1471,,3.00E-87,Q5HZT0,Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z),Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z),GO:0008409; GO:0050779; GO:0034353; GO:0003729; GO:0000287; GO:0071028; GO:0000166; GO:0005634,5'-3' exonuclease activity; RNA destabilization; RNA pyrophosphohydrolase activity; mRNA binding; magnesium ion binding; nuclear mRNA surveillance; nucleotide binding; nucleus,PF08652;,4.00E-37,CHOYP_BRAFLDRAFT_88205.1.1,,,,,,,DOM3Z_XENLA,Xenopus laevis (African clawed frog),metabolic process [GO:0008152]; mRNA catabolic process [GO:0006402]; nuclear mRNA surveillance [GO:0071028]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] comp144414_c0_seq1,2883,47.1384,0.43490695,281,260,,1.00E-172,Q5SRE5,Nucleoporin NUP188 homolog (hNup188),Nucleoporin NUP188 homolog (hNup188),GO:0005975; GO:0019221; GO:0015758; GO:0051028; GO:0007077; GO:0005635; GO:0005643; GO:0015031; GO:0010827; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear envelope; nuclear pore; protein transport; regulation of glucose transport; small molecule metabolic process; transmembrane transport; viral process,PF10487;,,,,,,,,,NU188_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp144414_c0_seq5,607,49.0939,0.49565352,11,6,,2.00E-42,Q5SRE5,Nucleoporin NUP188 homolog (hNup188),Nucleoporin NUP188 homolog (hNup188),GO:0005975; GO:0019221; GO:0015758; GO:0051028; GO:0007077; GO:0005635; GO:0005643; GO:0015031; GO:0010827; GO:0044281; GO:0055085; GO:0016032,carbohydrate metabolic process; cytokine-mediated signaling pathway; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; nuclear envelope; nuclear pore; protein transport; regulation of glucose transport; small molecule metabolic process; transmembrane transport; viral process,PF10487;,7.00E-16,CHOYP_NU188.2.2,,,,,,,NU188_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083] comp144416_c0_seq4,1682,45.1249,0.39872082,15,5,,6.00E-128,A8MWY0,UPF0577 protein KIAA1324-like (Estrogen-induced gene 121-like protein) (hEIG121L),UPF0577 protein KIAA1324-like (Estrogen-induced gene 121-like protein) (hEIG121L),GO:0016021,integral to membrane,,,,,,,,,,K132L_HUMAN,Homo sapiens (Human), comp144416_c0_seq5,1934,44.5191,0.43971574,75,24,,1.00E-142,Q3UZV7,UPF0577 protein KIAA1324-like homolog (Estrogen-induced gene 121-like protein) (EIG121L),UPF0577 protein KIAA1324-like homolog (Estrogen-induced gene 121-like protein) (EIG121L),GO:0016021,integral to membrane,,,,,,,,,,K132L_MOUSE,Mus musculus (Mouse), comp144417_c0_seq1,4689,38.2384,0.26379537,729,807,,3.00E-143,Q6ZU11,,,,,,4.00E-131,CHOYP_LOC101359921.2.2,,,,,,,YD002_HUMAN,, comp144418_c0_seq1,4967,36.3398,0.54448464,251,510,,5.00E-142,Q8WN55,Polypyrimidine tract-binding protein 1 (PTB),Polypyrimidine tract-binding protein 1 (PTB),GO:0003723; GO:0008380; GO:0006397; GO:0051148; GO:0000166; GO:0005634; GO:0000381,"RNA binding; RNA splicing; mRNA processing; negative regulation of muscle cell differentiation; nucleotide binding; nucleus; regulation of alternative mRNA splicing, via spliceosome",PF00076;,2.00E-127,CHOYP_LOC100745429.1.1,,,,,,,PTBP1_BOVIN,Bos taurus (Bovine),"mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" comp144418_c0_seq2,7121,34.321,0.53489301,3634,6754,,3.00E-140,Q8WN55,Polypyrimidine tract-binding protein 1 (PTB),Polypyrimidine tract-binding protein 1 (PTB),GO:0003723; GO:0008380; GO:0006397; GO:0051148; GO:0000166; GO:0005634; GO:0000381,"RNA binding; RNA splicing; mRNA processing; negative regulation of muscle cell differentiation; nucleotide binding; nucleus; regulation of alternative mRNA splicing, via spliceosome",PF00076;,7.00E-92,CHOYP_LOC100871266.1.1,,,,,,,PTBP1_BOVIN,Bos taurus (Bovine),"mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" comp144419_c0_seq1,2090,29.0431,0.62047492,326,704,,1.00E-27,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp144420_c0_seq1,736,41.9837,0.37222291,1,3,,3.00E-31,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144420_c0_seq2,1433,44.1731,0.3744428,2,5,,,,,,,,,1.00E-24,CHOYP_RN213.4.13,,,,,,,,, comp144420_c0_seq6,2905,43.7522,0.37418043,67,23,,8.00E-59,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,1.00E-20,CHOYP_RN213.8.13,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144421_c0_seq1,3488,31.9094,0.44739303,0,0,,4.00E-94,Q5ZIN1,Nuclear migration protein nudC (Nuclear distribution protein C homolog),Nuclear migration protein nudC (Nuclear distribution protein C homolog),GO:0051301; GO:0005737; GO:0005874; GO:0007067,cell division; cytoplasm; microtubule; mitosis,PF04969;PF16273;PF14050;,,,,,,,,,NUDC_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144421_c0_seq2,3525,31.8582,0.46652256,1,19,,6.00E-88,Q17QG2,Nuclear migration protein nudC (Nuclear distribution protein C homolog),Nuclear migration protein nudC (Nuclear distribution protein C homolog),GO:0051301; GO:0005737; GO:0005874; GO:0007067; GO:0005634,cell division; cytoplasm; microtubule; mitosis; nucleus,PF04969;PF16273;PF14050;,,,,,,,,,NUDC_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144421_c0_seq3,1900,35.8421,0.39502559,23,75,,,,,,,,,1.00E-55,CHOYP_RHO1.3.3,,,,,,,,, comp144421_c0_seq4,1888,35.8051,0.38105641,0,0,,,,,,,,,1.00E-55,CHOYP_RHO1.3.3,,,,,,,,, comp144421_c0_seq5,3509,31.8324,0.45804519,1,10,,4.00E-94,Q5ZIN1,Nuclear migration protein nudC (Nuclear distribution protein C homolog),Nuclear migration protein nudC (Nuclear distribution protein C homolog),GO:0051301; GO:0005737; GO:0005874; GO:0007067,cell division; cytoplasm; microtubule; mitosis,PF04969;PF16273;PF14050;,,,,,,,,,NUDC_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144421_c0_seq6,3505,31.8973,0.45702222,4,42,,4.00E-94,Q5ZIN1,Nuclear migration protein nudC (Nuclear distribution protein C homolog),Nuclear migration protein nudC (Nuclear distribution protein C homolog),GO:0051301; GO:0005737; GO:0005874; GO:0007067,cell division; cytoplasm; microtubule; mitosis,PF04969;PF16273;PF14050;,,,,,,,,,NUDC_CHICK,Gallus gallus (Chicken),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144422_c0_seq1,2614,36.5723,0.64499657,0,0,,8.00E-73,P34416,LIM and SH3 domain protein F42H10.3,LIM and SH3 domain protein F42H10.3,GO:0030054; GO:0055120; GO:0008270,cell junction; striated muscle dense body; zinc ion binding,PF00412;PF00880;PF00018;,7.00E-49,CHOYP_LOC663855.1.5,,,,,,,LASP1_CAEEL,Caenorhabditis elegans, comp144422_c0_seq10,2394,36.5497,0.67010348,3,18,,6.00E-15,P34416,LIM and SH3 domain protein F42H10.3,LIM and SH3 domain protein F42H10.3,GO:0030054; GO:0055120; GO:0008270,cell junction; striated muscle dense body; zinc ion binding,PF00412;PF00880;PF00018;,6.00E-17,CHOYP_LOC100631693.1.1,,,,,,,LASP1_CAEEL,Caenorhabditis elegans, comp144422_c0_seq4,2717,36.9525,0.64062041,0,0,,5.00E-55,Q9DC07,LIM zinc-binding domain-containing Nebulette (Actin-binding Z-disk protein),LIM zinc-binding domain-containing Nebulette (Actin-binding Z-disk protein),GO:0005737; GO:0008270,cytoplasm; zinc ion binding,PF00412;PF00880;PF14604;,7.00E-55,CHOYP_LOC663855.5.5,,,,,,,LNEBL_MOUSE,Mus musculus (Mouse), comp144422_c0_seq5,2724,37.1145,0.68759422,0,0,,7.00E-17,O76041,Nebulette (Actin-binding Z-disk protein),Nebulette (Actin-binding Z-disk protein),GO:0030018; GO:0051015; GO:0071691; GO:0001725; GO:0008307,Z disc; actin filament binding; cardiac muscle thin filament assembly; stress fiber; structural constituent of muscle,PF00880;PF14604;,6.00E-12,CHOYP_NEB.1.2,,,,,,,NEBL_HUMAN,Homo sapiens (Human),cardiac muscle thin filament assembly [GO:0071691] comp144422_c0_seq6,2613,36.8542,0.64702418,0,0,,2.00E-75,P34416,LIM and SH3 domain protein F42H10.3,LIM and SH3 domain protein F42H10.3,GO:0030054; GO:0055120; GO:0008270,cell junction; striated muscle dense body; zinc ion binding,PF00412;PF00880;PF00018;,1.00E-52,CHOYP_LOC663855.1.5,,,,,,,LASP1_CAEEL,Caenorhabditis elegans, comp144423_c1_seq1,4400,41.3864,0.63480911,42,29,,3.00E-80,P48996,Chromosome condensation protein dpy-27 (Protein dumpy-27),Chromosome condensation protein dpy-27 (Protein dumpy-27),GO:0005524; GO:0006310; GO:0006281; GO:0000805; GO:0030261; GO:0042464; GO:0046536; GO:0000228; GO:0043565; GO:0007062,ATP binding; DNA recombination; DNA repair; X chromosome; chromosome condensation; dosage compensation by hypoactivation of X chromosome; dosage compensation complex; nuclear chromosome; sequence-specific DNA binding; sister chromatid cohesion,PF06470;PF02463;,,,,,,,,,DPY27_CAEEL,Caenorhabditis elegans,chromosome condensation [GO:0030261]; dosage compensation by hypoactivation of X chromosome [GO:0042464] comp144423_c1_seq2,4445,41.1024,0.63172139,23,60,,0,P50532,Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome assembly protein XCAP-C) (Chromosome-associated protein C),Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome assembly protein XCAP-C) (Chromosome-associated protein C),GO:0005524; GO:0006310; GO:0006281; GO:0051301; GO:0005694; GO:0005829; GO:0007076; GO:0005634; GO:0046982; GO:0007062,ATP binding; DNA recombination; DNA repair; cell division; chromosome; cytosol; mitotic chromosome condensation; nucleus; protein heterodimerization activity; sister chromatid cohesion,PF06470;PF02463;,0,CHOYP_NEMVEDRAFT_V1G106520.1.1,,,8.00E-108,AM859381.p.cg.6,9,,SMC4_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp144424_c0_seq1,2753,47.0396,0.6144874,494,649,,0,P15215,Laminin subunit gamma-1 (Laminin B2 chain),Laminin subunit gamma-1 (Laminin B2 chain),GO:0005605; GO:0007155,basal lamina; cell adhesion,PF00052;PF00053;PF00055;,6.00E-126,CHOYP_PHUM_PHUM500930.1.1,,,,,,,LAMC1_DROME,Drosophila melanogaster (Fruit fly),basement membrane assembly [GO:0070831]; cell adhesion mediated by integrin [GO:0033627]; embryonic morphogenesis [GO:0048598]; endodermal digestive tract morphogenesis [GO:0061031]; extracellular matrix assembly [GO:0085029]; midgut development [GO:0007494]; organ morphogenesis [GO:0009887]; salivary gland morphogenesis [GO:0007435]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] comp144424_c0_seq2,3672,43.5185,0.43982483,154,536,,8.00E-13,P31696,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0007213; GO:0030548; GO:0005605; GO:0005509; GO:0030154; GO:0030054; GO:0035374; GO:0002162; GO:0043395; GO:0008201; GO:0016021; GO:0043236; GO:0007275; GO:0005886; GO:0032321; GO:0051491; GO:0045887; GO:0045944; GO:0043113; GO:0033691; GO:0045202; GO:0030297,G-protein coupled acetylcholine receptor signaling pathway; acetylcholine receptor regulator activity; basal lamina; calcium ion binding; cell differentiation; cell junction; chondroitin sulfate binding; dystroglycan binding; heparan sulfate proteoglycan binding; heparin binding; integral to membrane; laminin binding; multicellular organismal development; plasma membrane; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; sialic acid binding; synapse; transmembrane receptor protein tyrosine kinase activator activity,PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;,1.00E-72,CHOYP_PHUM_PHUM500930.1.1,,,,,,,AGRIN_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113] comp144424_c0_seq3,1689,49.2599,0.33354242,10,9,,1.00E-14,O00468,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0007213; GO:0005796; GO:0007411; GO:0005605; GO:0005509; GO:0005975; GO:0030054; GO:0035374; GO:0030204; GO:0045162; GO:0002162; GO:0030198; GO:0006024; GO:0006027; GO:0043395; GO:0016021; GO:0043236; GO:0043202; GO:0007603; GO:0005886; GO:0032321; GO:0051491; GO:0045887; GO:0045944; GO:0043113; GO:0001523; GO:0033691; GO:0005200; GO:0045202; GO:0050808,"G-protein coupled acetylcholine receptor signaling pathway; Golgi lumen; axon guidance; basal lamina; calcium ion binding; carbohydrate metabolic process; cell junction; chondroitin sulfate binding; chondroitin sulfate metabolic process; clustering of voltage-gated sodium channels; dystroglycan binding; extracellular matrix organization; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; heparan sulfate proteoglycan binding; integral to membrane; laminin binding; lysosomal lumen; phototransduction, visible light; plasma membrane; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; retinoid metabolic process; sialic acid binding; structural constituent of cytoskeleton; synapse; synapse organization",PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;,,,,,,,,,AGRIN_HUMAN,Homo sapiens (Human),clustering of voltage-gated sodium channels [GO:0045162]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]; retinoid metabolic process [GO:0001523]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp144424_c0_seq4,1526,48.2307,0.36178688,11,0,,3.00E-19,Q25092,Laminin subunit B (Fragment),Laminin subunit B (Fragment),GO:0005578,proteinaceous extracellular matrix,PF00053;,,,,,,,,,LAMB_HIRME,Hirudo medicinalis (Medicinal leech), comp144425_c0_seq4,1002,45.9082,0.5569667,116,191,,1.00E-157,P79101,Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73),Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73),GO:0008409; GO:0003723; GO:0004521; GO:0006398; GO:0005847; GO:0046872; GO:0030529,5'-3' exonuclease activity; RNA binding; endoribonuclease activity; histone mRNA 3'-end processing; mRNA cleavage and polyadenylation specificity factor complex; metal ion binding; ribonucleoprotein complex,PF10996;PF11718;PF00753;PF07521;,2.00E-144,CHOYP_BRAFLDRAFT_282200.1.1,,,,,,,CPSF3_BOVIN,Bos taurus (Bovine),mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398] comp144426_c0_seq1,4985,45.2758,0.68620067,1215,6602,,1.00E-09,Q5T200,Zinc finger CCCH domain-containing protein 13,Zinc finger CCCH domain-containing protein 13,GO:0046872,metal ion binding,PF00642;,,,,,,,,,ZC3HD_HUMAN,Homo sapiens (Human), comp144426_c0_seq2,1000,40.4,0.64943296,34,82,,1.00E-07,Q5T200,Zinc finger CCCH domain-containing protein 13,Zinc finger CCCH domain-containing protein 13,GO:0046872,metal ion binding,PF00642;,,,,,,,,,ZC3HD_HUMAN,Homo sapiens (Human), comp144427_c1_seq1,3131,39.6359,0.5044029,462,2435,,5.00E-131,Q9NZN8,CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2),CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2),GO:0030014; GO:0001104; GO:0001226; GO:0005829; GO:0031047; GO:0033147; GO:0000122; GO:0000289; GO:0005634; GO:0010606; GO:2000036; GO:0006417; GO:0001829,CCR4-NOT complex; RNA polymerase II transcription cofactor activity; RNA polymerase II transcription corepressor binding; cytosol; gene silencing by RNA; negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nuclear-transcribed mRNA poly(A) tail shortening; nucleus; positive regulation of cytoplasmic mRNA processing body assembly; regulation of stem cell maintenance; regulation of translation; trophectodermal cell differentiation,PF04153;,1.00E-90,CHOYP_CNOT2.1.2,,,,,,,CNOT2_HUMAN,Homo sapiens (Human),"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]" comp144428_c0_seq1,4438,41.0771,0.37115569,415,351,,0,P50533,Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E),Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E),GO:0005524; GO:0006310; GO:0006281; GO:0051301; GO:0000796; GO:0005829; GO:0007076; GO:0005634; GO:0007062,ATP binding; DNA recombination; DNA repair; cell division; condensin complex; cytosol; mitotic chromosome condensation; nucleus; sister chromatid cohesion,PF06470;PF02463;,0,CHOYP_SMC2.1.4,,,,,,,SMC2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp144428_c0_seq2,3280,41.1585,0.38374273,104,277,,0,P50533,Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E),Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E),GO:0005524; GO:0006310; GO:0006281; GO:0051301; GO:0000796; GO:0005829; GO:0007076; GO:0005634; GO:0007062,ATP binding; DNA recombination; DNA repair; cell division; condensin complex; cytosol; mitotic chromosome condensation; nucleus; sister chromatid cohesion,PF06470;PF02463;,0,CHOYP_SMC2.1.4,4.00E-13,ruditapes_c27792,,,,,SMC2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] comp144429_c0_seq1,3307,46.205,0.37613774,0,0,,8.00E-46,Q99MV7,RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007286; GO:0008270,"cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatid development; zinc ion binding",PF00567;,,,,,,,,,RNF17_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp144429_c0_seq12,1293,48.4919,0.30591035,0,0,,2.00E-10,Q5VCS6,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_MOUSE,Mus musculus (Mouse),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp144429_c0_seq13,5922,44.512,0.38563351,0,0,,2.00E-45,Q99MV7,RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007286; GO:0008270,"cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatid development; zinc ion binding",PF00567;,,,,,,,,,RNF17_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp144429_c0_seq14,3247,46.1349,0.36702543,0,0,,8.00E-46,Q99MV7,RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007286; GO:0008270,"cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatid development; zinc ion binding",PF00567;,,,,,,,,,RNF17_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp144429_c0_seq2,3235,46.2133,0.37285808,12,0,,3.00E-42,Q4R3G4,RING finger protein 17,RING finger protein 17,GO:0030154; GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007283; GO:0008270,"cell differentiation; cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatogenesis; zinc ion binding",PF00567;,,,,,,,,,RNF17_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp144429_c0_seq3,1870,42.9947,0.4194546,0,0,,5.00E-10,Q9Y2W6,Tudor and KH domain-containing protein (Tudor domain-containing protein 2),Tudor and KH domain-containing protein (Tudor domain-containing protein 2),GO:0043046; GO:0003723; GO:0030154; GO:0009566; GO:0031047; GO:0007140; GO:0005739; GO:0071546; GO:0071547; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; RNA binding; cell differentiation; fertilization; gene silencing by RNA; male meiosis; mitochondrion; pi-body; piP-body; piRNA metabolic process; spermatogenesis,PF00013;PF00567;,,,,,,,,,TDRKH_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp144429_c0_seq4,5979,44.4389,0.38632215,0,0,,3.00E-45,Q99MV7,RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007286; GO:0008270,"cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatid development; zinc ion binding",PF00567;,,,,,,,,,RNF17_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp144429_c0_seq5,5910,44.5178,0.38624341,0,0,,8.00E-42,Q4R3G4,RING finger protein 17,RING finger protein 17,GO:0030154; GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007283; GO:0008270,"cell differentiation; cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatogenesis; zinc ion binding",PF00567;,,,,,,,,,RNF17_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp144429_c0_seq6,1810,42.8177,0.41315417,0,0,,3.00E-08,Q9UJV3,Probable E3 ubiquitin-protein ligase MID2 (EC 6.3.2.-) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (Tripartite motif-containing protein 1),Probable E3 ubiquitin-protein ligase MID2 (EC 6.3.2.-) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (Tripartite motif-containing protein 1),GO:0005813; GO:0005737; GO:0016874; GO:0005874; GO:0016567; GO:0008270,centrosome; cytoplasm; ligase activity; microtubule; protein ubiquitination; zinc ion binding,PF00622;PF00643;PF13445;,,,,,,,,,TRIM1_HUMAN,Homo sapiens (Human),innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567] comp144429_c0_seq7,5785,44.5635,0.37966434,0,0,,2.00E-45,Q99MV7,RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2),GO:0005737; GO:0016788; GO:0007275; GO:0003676; GO:0005634; GO:0007286; GO:0008270,"cytoplasm; hydrolase activity, acting on ester bonds; multicellular organismal development; nucleic acid binding; nucleus; spermatid development; zinc ion binding",PF00567;,,,,,,,,,RNF17_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; spermatid development [GO:0007286] comp144429_c0_seq8,941,47.6089,0.2867525,8,4,,2.00E-10,D2H3M0,Tudor domain-containing protein 5,Tudor domain-containing protein 5,GO:0043046; GO:0030719; GO:0033391; GO:0071546; GO:0007286,DNA methylation involved in gamete generation; P granule organization; chromatoid body; pi-body; spermatid development,PF12872;PF00567;,,,,,,,,,TDRD5_AILME,Ailuropoda melanoleuca (Giant panda),DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286] comp144429_c0_seq9,1993,42.9503,0.43834062,0,0,,3.00E-11,Q09654,E3 ubiquitin-protein ligase arc-1 (EC 6.3.2.-) (Putative GTP-binding protein trim-23 homolog),E3 ubiquitin-protein ligase arc-1 (EC 6.3.2.-) (Putative GTP-binding protein trim-23 homolog),GO:0005525; GO:0005622; GO:0016874; GO:0046872; GO:0016567; GO:0007264; GO:0008270,GTP binding; intracellular; ligase activity; metal ion binding; protein ubiquitination; small GTPase mediated signal transduction; zinc ion binding,PF00025;PF00643;PF13445;,,,,,,,,,TRI23_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264] comp144430_c0_seq1,3200,35.7188,0.68291702,11,176,,,,,,,,,3.00E-86,CHOYP_UFD1L.1.1,,,,,,,,, comp144430_c0_seq2,3245,35.7165,0.6726795,6,130,,2.00E-111,Q92890,Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1),Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1),GO:0005829; GO:0005634; GO:0043161; GO:0001501; GO:0006511; GO:0004843,cytosol; nucleus; proteasomal ubiquitin-dependent protein catabolic process; skeletal system development; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF03152;,,,2.00E-41,ruditapes_c15566,,,,,UFD1_HUMAN,Homo sapiens (Human),"ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; retrograde protein transport, ER to cytosol [GO:0030970]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp144431_c0_seq1,3204,35.1748,0.56945243,29,98,,1.00E-82,Q63679,Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) (Testis-specific gene A protein) (Zinc finger protein TSGA),Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) (Testis-specific gene A protein) (Zinc finger protein TSGA),GO:0030154; GO:0016568; GO:0005737; GO:0051213; GO:0046872; GO:0005634; GO:0006355; GO:0007283; GO:0006351,"cell differentiation; chromatin modification; cytoplasm; dioxygenase activity; metal ion binding; nucleus; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF02373;,8.00E-81,CHOYP_LOC100378099.1.1,,,,,,,KDM3A_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; chromatin modification [GO:0016568]; male gonad development [GO:0008584]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp144431_c0_seq2,3235,35.3323,0.56918743,95,418,,2.00E-85,Q6ZPY7,Lysine-specific demethylase 3B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B),Lysine-specific demethylase 3B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B),GO:0016568; GO:0051213; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; dioxygenase activity; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02373;,,,,,,,,,KDM3B_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144431_c0_seq3,3633,43.9031,0.6113767,483,646,,2.00E-107,Q69ZK6,Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C),Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C),GO:0016568; GO:0051213; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; dioxygenase activity; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02373;,2.00E-100,CHOYP_LOC100378099.1.1,1.00E-76,ruditapes_c9997,,,,,JHD2C_MOUSE,Mus musculus (Mouse),"chromatin modification [GO:0016568]; epithelial cell morphogenesis [GO:0003382]; maintenance of cell number [GO:0098727]; male germ-line stem cell population maintenance [GO:0036098]; male gonad development [GO:0008584]; regulation of transcription, DNA-templated [GO:0006355]; reproductive senescence [GO:1990636]; seminiferous tubule development [GO:0072520]; transcription, DNA-templated [GO:0006351]" comp144432_c0_seq1,6209,41.9069,0.48288697,918,474,,0,F1RCR6,E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12),GO:0006281; GO:0009790; GO:2000780; GO:1901315; GO:0005654; GO:0042787; GO:0006974; GO:0004842,DNA repair; embryo development; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; nucleoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; ubiquitin-protein ligase activity,PF00632;,0,CHOYP_TRIPC.1.1,1.00E-84,ruditapes_c23316,,,,,TRIPC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144434_c0_seq1,7716,40.1633,0.38866948,737,0,male,3.00E-144,Q6VVW5,Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),GO:0005524; GO:0005525; GO:0060348; GO:0097011; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0001503; GO:0017046; GO:0005886; GO:0004672; GO:0007168,ATP binding; GTP binding; bone development; cellular response to granulocyte macrophage colony-stimulating factor stimulus; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; ossification; peptide hormone binding; plasma membrane; protein kinase activity; receptor guanylyl cyclase signaling pathway,PF01094;PF00211;PF07714;,1.00E-178,CHOYP_LOC100197876.1.1,,,,,,,ANPRB_MOUSE,Mus musculus (Mouse),bone development [GO:0060348]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]; single organism reproductive process [GO:0044702] comp144434_c0_seq2,7727,40.1579,0.38821296,646,22,,8.00E-144,P46197,Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),GO:0005524; GO:0005525; GO:0004383; GO:0042802; GO:0016021; GO:0035556; GO:0016941; GO:0001503; GO:0004672,ATP binding; GTP binding; guanylate cyclase activity; identical protein binding; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; ossification; protein kinase activity,PF01094;PF00211;PF07714;,1.00E-178,CHOYP_LOC100197876.1.1,3.00E-24,ruditapes_c18931,,,,,ANPRB_BOVIN,Bos taurus (Bovine),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168] comp144435_c0_seq1,5625,47.3778,0.63794701,14,7,,2.00E-137,Q868Z9,Papilin,Papilin,GO:0005604; GO:0030198; GO:0005201; GO:0004222; GO:0007275; GO:0004867; GO:0008270,basement membrane; extracellular matrix organization; extracellular matrix structural constituent; metalloendopeptidase activity; multicellular organismal development; serine-type endopeptidase inhibitor activity; zinc ion binding,PF05986;PF07679;PF00014;PF08686;PF00090;,,,,,,,,,PPN_DROME,Drosophila melanogaster (Fruit fly),extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275] comp144435_c0_seq2,5753,46.8625,0.63259736,9,18,,3.00E-18,Q9Z2I4,Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1),Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1),GO:0030424; GO:0016199; GO:0016021; GO:0001764; GO:0005886,axon; axon midline choice point recognition; integral to membrane; neuron migration; plasma membrane,PF00041;PF07679;,,,,,,,,,ROBO3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; chemoattraction of axon [GO:0061642]; chemorepulsion of axon [GO:0061643]; commissural neuron axon guidance [GO:0071679]; neuron migration [GO:0001764]; Roundabout signaling pathway [GO:0035385] comp144435_c0_seq3,2020,45.2475,0.63409905,63,7,,2.00E-26,P83606,Kunitz-type serine protease inhibitor 6 (BmTI-6) (Fragment),Kunitz-type serine protease inhibitor 6 (BmTI-6) (Fragment),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,BMTI6_BOOMI,Rhipicephalus microplus (Cattle tick) (Boophilus microplus), comp144435_c0_seq4,5576,46.9692,0.62676271,0,0,,1.00E-12,P36335,Neural cell adhesion molecule 1-B (N-CAM-1-B) (NCAM-1-B),Neural cell adhesion molecule 1-B (N-CAM-1-B) (NCAM-1-B),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;,,,,,,,,,NCA12_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167] comp144435_c0_seq6,1304,46.2423,0.5928404,0,3,,1.00E-26,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp144435_c0_seq7,5448,47.4853,0.62595833,0,0,,4.00E-109,Q868Z9,Papilin,Papilin,GO:0005604; GO:0030198; GO:0005201; GO:0004222; GO:0007275; GO:0004867; GO:0008270,basement membrane; extracellular matrix organization; extracellular matrix structural constituent; metalloendopeptidase activity; multicellular organismal development; serine-type endopeptidase inhibitor activity; zinc ion binding,PF05986;PF07679;PF00014;PF08686;PF00090;,,,,,,,,,PPN_DROME,Drosophila melanogaster (Fruit fly),extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275] comp144435_c0_seq8,394,49.2386,0.35406391,8,1,,8.00E-10,Q868Z9,Papilin,Papilin,GO:0005604; GO:0030198; GO:0005201; GO:0004222; GO:0007275; GO:0004867; GO:0008270,basement membrane; extracellular matrix organization; extracellular matrix structural constituent; metalloendopeptidase activity; multicellular organismal development; serine-type endopeptidase inhibitor activity; zinc ion binding,PF05986;PF07679;PF00014;PF08686;PF00090;,,,,,,,,,PPN_DROME,Drosophila melanogaster (Fruit fly),extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275] comp144437_c0_seq11,351,49.5726,0.2791827,24,8,,3.00E-22,Q6R2W3,SCAN domain-containing protein 3 (Protein ZNF452) (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9),SCAN domain-containing protein 3 (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9),GO:0015074; GO:0003676; GO:0005634; GO:0003700,DNA integration; nucleic acid binding; nucleus; sequence-specific DNA binding transcription factor activity,PF14291;PF02023;,,,,,,,,,SCND3_HUMAN,Homo sapiens (Human),DNA integration [GO:0015074] comp144437_c0_seq16,1304,46.6258,0.39622665,0,0,,2.00E-16,Q6R2W3,SCAN domain-containing protein 3 (Protein ZNF452) (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9),SCAN domain-containing protein 3 (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9),GO:0015074; GO:0003676; GO:0005634; GO:0003700,DNA integration; nucleic acid binding; nucleus; sequence-specific DNA binding transcription factor activity,PF14291;PF02023;,,,,,,,,,SCND3_HUMAN,Homo sapiens (Human),DNA integration [GO:0015074] comp144437_c0_seq17,1539,45.5491,0.39360228,0,0,,7.00E-22,Q6ZNG9,KRAB-A domain-containing protein 2,KRAB-A domain-containing protein 2,GO:0015074; GO:0005622; GO:0003676; GO:0006355,"DNA integration; intracellular; nucleic acid binding; regulation of transcription, DNA-dependent",PF01352;,,,,,,,,,KRBA2_HUMAN,Homo sapiens (Human),"DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]" comp144437_c0_seq5,1323,46.6364,0.40433038,2,0,,3.00E-22,Q6ZNG9,KRAB-A domain-containing protein 2,KRAB-A domain-containing protein 2,GO:0015074; GO:0005622; GO:0003676; GO:0006355,"DNA integration; intracellular; nucleic acid binding; regulation of transcription, DNA-dependent",PF01352;,,,,,,,,,KRBA2_HUMAN,Homo sapiens (Human),"DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]" comp144437_c0_seq7,1558,45.5712,0.40094853,0,0,,8.00E-22,Q6ZNG9,KRAB-A domain-containing protein 2,KRAB-A domain-containing protein 2,GO:0015074; GO:0005622; GO:0003676; GO:0006355,"DNA integration; intracellular; nucleic acid binding; regulation of transcription, DNA-dependent",PF01352;,,,,,,,,,KRBA2_HUMAN,Homo sapiens (Human),"DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]" comp144439_c0_seq1,3797,41.4274,0.64399167,0,31,,4.00E-20,P53352,Inner centromere protein,Inner centromere protein,GO:0005721; GO:0007059; GO:0000910; GO:0005737; GO:0005874; GO:0007067; GO:0005634; GO:0005819,centromeric heterochromatin; chromosome segregation; cytokinesis; cytoplasm; microtubule; mitosis; nucleus; spindle,PF03941;PF12178;,,,,,,,,,INCE_CHICK,Gallus gallus (Chicken),chromosome segregation [GO:0007059]; cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067] comp144439_c0_seq4,4502,39.3381,0.6321249,70,120,,5.00E-20,P53352,Inner centromere protein,Inner centromere protein,GO:0005721; GO:0007059; GO:0000910; GO:0005737; GO:0005874; GO:0007067; GO:0005634; GO:0005819,centromeric heterochromatin; chromosome segregation; cytokinesis; cytoplasm; microtubule; mitosis; nucleus; spindle,PF03941;PF12178;,,,,,,,,,INCE_CHICK,Gallus gallus (Chicken),chromosome segregation [GO:0007059]; cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067] comp144440_c0_seq1,5256,44.9201,0.55773366,79,488,,0,O57683,Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155),Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155),GO:0008380; GO:0006397; GO:0005681,RNA splicing; mRNA processing; spliceosomal complex,PF08920;,,,,,,,,,SF3B1_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144440_c0_seq2,5229,44.999,0.5584563,155,369,,0,O57683,Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155),Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155),GO:0008380; GO:0006397; GO:0005681,RNA splicing; mRNA processing; spliceosomal complex,PF08920;,0,CHOYP_SF3B1.1.3,3.00E-35,ruditapes_c18632,,,,,SF3B1_XENLA,Xenopus laevis (African clawed frog),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144442_c0_seq2,4201,39.9191,0.47856592,1297,6669,,0,A0JP85,CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1),CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1),GO:0030014; GO:0000932; GO:0030331; GO:0031047; GO:0033147; GO:0048387; GO:0000122; GO:0005634; GO:0010606; GO:1900153; GO:0060213; GO:0006417; GO:0042974; GO:0006351,"CCR4-NOT complex; cytoplasmic mRNA processing body; estrogen receptor binding; gene silencing by RNA; negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of retinoic acid receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of cytoplasmic mRNA processing body assembly; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; regulation of translation; retinoic acid receptor binding; transcription, DNA-dependent",PF16415;PF16418;PF16417;PF12842;PF04054;,0,CHOYP_CNOT1.1.1,,,,,,,CNOT1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"gene silencing by RNA [GO:0031047]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; transcription, DNA-templated [GO:0006351]" comp144444_c0_seq11,500,48.6,0.61640711,0,0,,,,,,,,,6.00E-22,CHOYP_LOC100186299.3.6,,,,,,,,, comp144444_c0_seq2,1423,49.0513,0.55963637,0,0,,4.00E-14,Q99996,A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),GO:0000086; GO:0005794; GO:0005813; GO:0005829; GO:0000242; GO:0032947; GO:0005102; GO:0007165; GO:0007268; GO:0006810; GO:0008076,G2/M transition of mitotic cell cycle; Golgi apparatus; centrosome; cytosol; pericentriolar material; protein complex scaffold; receptor binding; signal transduction; synaptic transmission; transport; voltage-gated potassium channel complex,PF10495;,5.00E-28,CHOYP_LOC100186299.2.6,,,,,,,AKAP9_HUMAN,Homo sapiens (Human),cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810] comp144444_c0_seq6,1580,47.7848,0.57452426,0,0,,4.00E-14,Q99996,A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),GO:0000086; GO:0005794; GO:0005813; GO:0005829; GO:0000242; GO:0032947; GO:0005102; GO:0007165; GO:0007268; GO:0006810; GO:0008076,G2/M transition of mitotic cell cycle; Golgi apparatus; centrosome; cytosol; pericentriolar material; protein complex scaffold; receptor binding; signal transduction; synaptic transmission; transport; voltage-gated potassium channel complex,PF10495;,7.00E-27,CHOYP_TVAG_193760.2.4,,,,,,,AKAP9_HUMAN,Homo sapiens (Human),cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810] comp144447_c1_seq2,4204,45.5994,0.36620469,40,105,,,,,,,,,,,2.00E-49,ruditapes_c15841,,,,,,, comp144447_c1_seq5,4006,45.5317,0.35187052,0,27,,4.00E-101,Q8R4Y8,Rotatin,Rotatin,GO:0036064; GO:0005737; GO:0007368; GO:0016021,cilium basal body; cytoplasm; determination of left/right symmetry; integral to membrane,PF14726;,2.00E-82,CHOYP_RTTN.2.3,,,,,,,RTTN_MOUSE,Mus musculus (Mouse),cilium organization [GO:0044782]; determination of left/right symmetry [GO:0007368] comp144449_c0_seq5,377,48.5411,0.67742412,0,12,,2.00E-14,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,6.00E-20,CHOYP_LOC100491442.1.2,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144449_c0_seq7,397,46.0957,0.61801634,3,0,,1.00E-15,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,7.00E-20,CHOYP_HARB1.2.3,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144451_c0_seq1,2470,40.5263,0.47462193,431,1823,,0,Q9VUV9,Putative U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13),Putative U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Protein lethal (3) 72Ab),GO:0005524; GO:0004004; GO:0071013; GO:0000398; GO:0007067; GO:0003676; GO:0071011; GO:0000381,"ATP binding; ATP-dependent RNA helicase activity; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; mitosis; nucleic acid binding; precatalytic spliceosome; regulation of alternative mRNA splicing, via spliceosome",PF00270;PF00271;PF02889;,0,CHOYP_U520.1.1,,,,,,,U520_DROME,Drosophila melanogaster (Fruit fly),"mitotic nuclear division [GO:0007067]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; ventral cord development [GO:0007419]" comp144451_c0_seq2,1504,47.2074,0.53760264,294,202,,0,O75643,U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD),U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD),GO:0005524; GO:0004004; GO:0005682; GO:0071013; GO:0000354; GO:0003676; GO:0005654,ATP binding; ATP-dependent RNA helicase activity; U5 snRNP; catalytic step 2 spliceosome; cis assembly of pre-catalytic spliceosome; nucleic acid binding; nucleoplasm,PF00270;PF00271;PF02889;,,,,,,,,,U520_HUMAN,Homo sapiens (Human),"cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]" comp144456_c1_seq2,1987,43.4323,0.49330037,73,380,,0,Q9CSH3,Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44),Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44),GO:0000175; GO:0071034; GO:0003723; GO:0005737; GO:0004519; GO:0005085; GO:0000176; GO:0005730; GO:0005654; GO:0016075; GO:0006364,3'-5'-exoribonuclease activity; CUT catabolic process; RNA binding; cytoplasm; endonuclease activity; guanyl-nucleotide exchange factor activity; nuclear exosome (RNase complex); nucleolus; nucleoplasm; rRNA catabolic process; rRNA processing,PF13638;,0,CHOYP_DIS3.1.1,,,,,,,RRP44_MOUSE,Mus musculus (Mouse),CUT catabolic process [GO:0071034]; mRNA catabolic process [GO:0006402]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364] comp144456_c1_seq3,1207,42.005,0.56420515,203,822,,2.00E-09,O74454,Protein sts5,Protein sts5,GO:0006401; GO:0007049; GO:0032153; GO:0034613; GO:0005829; GO:0004527; GO:0090305; GO:2000115,RNA catabolic process; cell cycle; cell division site; cellular protein localization; cytosol; exonuclease activity; nucleic acid phosphodiester bond hydrolysis; regulation of maintenance of bipolar cell polarity regulating cell shape,,5.00E-34,CHOYP_contig_039310,,,,,,,STS5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell cycle [GO:0007049]; mRNA catabolic process [GO:0006402]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364] comp144457_c0_seq1,4746,41.2769,0.56116444,1567,3960,,0,Q8WVM7,Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1),Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1),GO:0051301; GO:0030054; GO:0000785; GO:0007059; GO:0000775; GO:0005829; GO:0007067; GO:0000278; GO:0005654,"cell division; cell junction; chromatin; chromosome segregation; chromosome, centromeric region; cytosol; mitosis; mitotic cell cycle; nucleoplasm",PF08514;,0,CHOYP_ISCW_ISCW017188.1.1,,,,,,,STAG1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein sumoylation [GO:0016925]; sister chromatid cohesion [GO:0007062] comp144458_c0_seq1,5220,37.3563,0.44613209,77,454,,0,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,0,CHOYP_SMP_089460.1.1.1,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp144458_c0_seq2,5215,37.2771,0.45422695,0,0,,0,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,0,CHOYP_LOC100882339.2.2,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp144458_c0_seq3,4476,38.5389,0.4284363,0,52,,0,P20807,Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1),Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1),GO:0070315; GO:0030315; GO:0030018; GO:0006915; GO:0001896; GO:0005509; GO:0004198; GO:0071277; GO:0071472; GO:0005829; GO:0055103; GO:0046716; GO:0007517; GO:0043066; GO:0033234; GO:0045892; GO:0005634; GO:0051092; GO:0045862; GO:0051281; GO:0014718; GO:0045893; GO:0043234; GO:0006461; GO:0032947; GO:0072657; GO:0043122; GO:0045661; GO:0014850; GO:0045214; GO:0097264; GO:0004871; GO:0031402; GO:0008307,"G1 to G0 transition involved in cell differentiation; T-tubule; Z disc; apoptotic process; autolysis; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cellular response to calcium ion; cellular response to salt stress; cytosol; ligase regulator activity; muscle cell cellular homeostasis; muscle organ development; negative regulation of apoptotic process; negative regulation of protein sumoylation; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of proteolysis; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of satellite cell activation involved in skeletal muscle regeneration; positive regulation of transcription, DNA-dependent; protein complex; protein complex assembly; protein complex scaffold; protein localization to membrane; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of myoblast differentiation; response to muscle activity; sarcomere organization; self proteolysis; signal transducer activity; sodium ion binding; structural constituent of muscle",PF01067;PF13202;PF13833;PF00648;,0,CHOYP_LOC100882339.2.2,,,,,,,CAN3_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; cellular response to calcium ion [GO:0071277]; cellular response to salt stress [GO:0071472]; G1 to G0 transition involved in cell differentiation [GO:0070315]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of satellite cell activation involved in skeletal muscle regeneration [GO:0014718]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex assembly [GO:0006461]; protein localization to membrane [GO:0072657]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of myoblast differentiation [GO:0045661]; response to calcium ion [GO:0051592]; response to muscle activity [GO:0014850]; sarcomere organization [GO:0045214]; self proteolysis [GO:0097264]" comp144458_c0_seq4,5211,37.3441,0.45281442,0,0,,0,O35920,Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4),Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4),GO:0005509; GO:0004198; GO:0005622; GO:0006508,calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; intracellular; proteolysis,PF01067;PF13833;PF00648;,,,,,,,,,CAN9_RAT,Rattus norvegicus (Rat),digestion [GO:0007586] comp144458_c0_seq5,5184,37.2685,0.44019306,0,0,,0,Q11002,Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit],Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit],GO:0021919; GO:0015629; GO:0005509; GO:0004198; GO:0042335; GO:0005737; GO:0008340; GO:0043025; GO:0006909; GO:0016540; GO:0006508,BMP signaling pathway involved in spinal cord dorsal/ventral patterning; actin cytoskeleton; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cuticle development; cytoplasm; determination of adult lifespan; neuronal cell body; phagocytosis; protein autoprocessing; proteolysis,PF01067;PF00648;,0,CHOYP_SMP_089460.1.1.1,,,,,,,CANA_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; BMP signaling pathway involved in spinal cord dorsal/ventral patterning [GO:0021919]; cuticle development [GO:0042335]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; dorsal/ventral pattern formation [GO:0009953]; phagocytosis [GO:0006909]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] comp144458_c0_seq6,5197,37.31,0.45497457,2,17,,0,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,0,CHOYP_SMP_089460.1.1.1,5.00E-26,ruditapes_c21915,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp144458_c0_seq7,3693,40.4278,0.44676807,0,9,,0,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,0,CHOYP_LOC100882339.2.2,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp144458_c0_seq8,3784,40.5655,0.43962343,0,0,,0,O35920,Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4),Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4),GO:0005509; GO:0004198; GO:0005622; GO:0006508,calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; intracellular; proteolysis,PF01067;PF13833;PF00648;,2.00E-14,CHOYP_CAN5.1.1,,,,,,,CAN9_RAT,Rattus norvegicus (Rat),digestion [GO:0007586] comp144460_c0_seq1,5047,42.9166,0.44712408,23,6,,3.00E-170,B5DE93,Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12),Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12),GO:0005524; GO:0008353; GO:0008380; GO:0004693; GO:0006397; GO:0019908; GO:0016607; GO:0070816; GO:0043405,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; RNA splicing; cyclin-dependent protein serine/threonine kinase activity; mRNA processing; nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; phosphorylation of RNA polymerase II C-terminal domain; regulation of MAP kinase activity,PF00069;,0,CHOYP_CDK13.1.1,,,,,,,CDK12_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of MAP kinase activity [GO:0043405]; RNA splicing [GO:0008380] comp144460_c0_seq3,5047,42.9364,0.44676057,2,0,,1.00E-160,Q9VP22,Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12) (dCdk12),Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12) (dCdk12),GO:0005524; GO:0008353; GO:0004693; GO:0022008; GO:0000228; GO:0019908; GO:0006909; GO:0070816; GO:0005703,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein serine/threonine kinase activity; neurogenesis; nuclear chromosome; nuclear cyclin-dependent protein kinase holoenzyme complex; phagocytosis; phosphorylation of RNA polymerase II C-terminal domain; polytene chromosome puff,PF00069;,0,CHOYP_CDK13.1.1,,,,,,,CDK12_DROME,Drosophila melanogaster (Fruit fly),neurogenesis [GO:0022008]; phagocytosis [GO:0006909]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of Ras protein signal transduction [GO:0046579]; protein phosphorylation [GO:0006468] comp144460_c0_seq4,5066,42.8741,0.45088953,7,9,,2.00E-169,B5DE93,Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12),Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12),GO:0005524; GO:0008353; GO:0008380; GO:0004693; GO:0006397; GO:0019908; GO:0016607; GO:0070816; GO:0043405,ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; RNA splicing; cyclin-dependent protein serine/threonine kinase activity; mRNA processing; nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; phosphorylation of RNA polymerase II C-terminal domain; regulation of MAP kinase activity,PF00069;,,,,,,,,,CDK12_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of MAP kinase activity [GO:0043405]; RNA splicing [GO:0008380] comp144460_c0_seq5,5066,42.8148,0.44748697,8,17,,5.00E-164,Q14004,Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller),Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller),GO:0005524; GO:0008353; GO:0000380; GO:0002945; GO:0004693; GO:0030097; GO:0019048; GO:0019908; GO:0016607; GO:0070816; GO:0008284; GO:0007088,"ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; alternative mRNA splicing, via spliceosome; cyclin K-CDK13 complex; cyclin-dependent protein serine/threonine kinase activity; hemopoiesis; modulation by virus of host morphology or physiology; nuclear cyclin-dependent protein kinase holoenzyme complex; nuclear speck; phosphorylation of RNA polymerase II C-terminal domain; positive regulation of cell proliferation; regulation of mitosis",PF00069;,0,CHOYP_CDK13.1.1,,,,,,,CDK13_HUMAN,Homo sapiens (Human),"alternative mRNA splicing, via spliceosome [GO:0000380]; hemopoiesis [GO:0030097]; multicellular organism development [GO:0007275]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cell proliferation [GO:0008284]; regulation of mitotic nuclear division [GO:0007088]; viral process [GO:0016032]" comp144461_c0_seq1,2797,49.4816,0.47520387,7,1,,3.00E-78,P0CE94,Talin-A (Filopodin),Talin-A (Filopodin),GO:0005938; GO:0000902; GO:0016337; GO:0031589; GO:0005856; GO:0032433; GO:0016020; GO:0000281; GO:0006909; GO:0030587,cell cortex; cell morphogenesis; cell-cell adhesion; cell-substrate adhesion; cytoskeleton; filopodium tip; membrane; mitotic cytokinesis; phagocytosis; sorocarp development,PF16511;PF00373;PF09379;,0,CHOYP_TLN1.4.4,,,,,,,TALA_DICDI,Dictyostelium discoideum (Slime mold),actomyosin contractile ring contraction [GO:0000916]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; cleavage furrow ingression [GO:0036090]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; single organismal cell-cell adhesion [GO:0016337]; sorocarp development [GO:0030587]; uropod retraction [GO:0034461] comp144461_c0_seq2,2260,50.4867,0.44506788,7,0,,1.00E-06,Q86UX7,Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2),Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2),GO:0030054; GO:0042995; GO:0033622; GO:0005178; GO:0007159; GO:0005543; GO:0070527; GO:0002102; GO:0033632,cell junction; cell projection; integrin activation; integrin binding; leukocyte cell-cell adhesion; phospholipid binding; platelet aggregation; podosome; regulation of cell-cell adhesion mediated by integrin,PF00373;PF00169;,6.00E-68,CHOYP_TLN1.2.4,,,,,,,URP2_HUMAN,Homo sapiens (Human),integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; substrate adhesion-dependent cell spreading [GO:0034446] comp144461_c0_seq4,3382,48.9651,0.49764055,0,0,,0,P54939,Talin-1,Talin-1,GO:0015629; GO:0007155; GO:0009986; GO:0007016; GO:0005829; GO:0005925; GO:0001726; GO:0032587; GO:0005200,actin cytoskeleton; cell adhesion; cell surface; cytoskeletal anchoring at plasma membrane; cytosol; focal adhesion; ruffle; ruffle membrane; structural constituent of cytoskeleton,PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;,0,CHOYP_TLN2.1.2,,,,,,,TLN1_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016] comp144461_c0_seq5,1014,47.14,0.64334446,0,0,,,,,,,,,6.00E-19,CHOYP_TLN1.1.4,,,,,,,,, comp144461_c0_seq7,3252,49.7232,0.49930167,0,0,,0,P54939,Talin-1,Talin-1,GO:0015629; GO:0007155; GO:0009986; GO:0007016; GO:0005829; GO:0005925; GO:0001726; GO:0032587; GO:0005200,actin cytoskeleton; cell adhesion; cell surface; cytoskeletal anchoring at plasma membrane; cytosol; focal adhesion; ruffle; ruffle membrane; structural constituent of cytoskeleton,PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;,9.00E-112,CHOYP_LOC100742957.1.1,,,3.00E-87,CU999937.p.cg.6,10,,TLN1_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016] comp144461_c1_seq1,2767,50.0904,0.52488921,1051,438,,9.00E-20,Q9ERE8,Mesoderm development candidate 1,Mesoderm development candidate 1,,,,0,CHOYP_TLN1.4.4,,,,,,,MESD1_MOUSE,Mus musculus (Mouse), comp144461_c1_seq2,692,47.6879,0.59605225,108,126,,2.00E-08,P33338,Protein SLA2 (Transmembrane protein MOP2),Protein SLA2 (Transmembrane protein MOP2),GO:0030479; GO:0007015; GO:0007121; GO:0005934; GO:0006897; GO:0006887; GO:0031505; GO:0000131; GO:0016021; GO:0005543; GO:0005886; GO:0030674,"actin cortical patch; actin filament organization; bipolar cellular bud site selection; cellular bud tip; endocytosis; exocytosis; fungal-type cell wall organization; incipient cellular bud site; integral to membrane; phospholipid binding; plasma membrane; protein binding, bridging",PF07651;PF01608;,,,,,,,,,SLA2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),actin filament organization [GO:0007015]; bipolar cellular bud site selection [GO:0007121]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; fungal-type cell wall organization [GO:0031505] comp144461_c1_seq5,2318,51.855,0.69423452,314,373,,2.00E-14,O00291,Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I),Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I),GO:0005794; GO:0006919; GO:0097190; GO:0030154; GO:0030276; GO:0048268; GO:0030136; GO:0030665; GO:0005856; GO:0006897; GO:0012505; GO:0016020; GO:0005634; GO:0035091; GO:0048260; GO:0006355; GO:0005200; GO:0006351,"Golgi apparatus; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic signaling pathway; cell differentiation; clathrin binding; clathrin coat assembly; clathrin-coated vesicle; clathrin-coated vesicle membrane; cytoskeleton; endocytosis; endomembrane system; membrane; nucleus; phosphatidylinositol binding; positive regulation of receptor-mediated endocytosis; regulation of transcription, DNA-dependent; structural constituent of cytoskeleton; transcription, DNA-dependent",PF07651;PF16515;PF01608;,5.00E-170,CHOYP_TLN1.4.4,,,,,,,HIP1_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of apoptotic process [GO:0042981]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144461_c1_seq7,560,51.9643,0.76871347,163,153,,9.00E-71,Q9Y490,Talin-1,Talin-1,GO:0015629; GO:0006987; GO:0007411; GO:0007155; GO:0009986; GO:0005911; GO:0007043; GO:0007044; GO:0044267; GO:0005813; GO:0030866; GO:0007016; GO:0005829; GO:0070062; GO:0005925; GO:0043231; GO:0006936; GO:0005886; GO:0030168; GO:0002576; GO:0001726; GO:0032587; GO:0005200,actin cytoskeleton; activation of signaling protein activity involved in unfolded protein response; axon guidance; cell adhesion; cell surface; cell-cell junction; cell-cell junction assembly; cell-substrate junction assembly; cellular protein metabolic process; centrosome; cortical actin cytoskeleton organization; cytoskeletal anchoring at plasma membrane; cytosol; extracellular vesicular exosome; focal adhesion; intracellular membrane-bounded organelle; muscle contraction; plasma membrane; platelet activation; platelet degranulation; ruffle; ruffle membrane; structural constituent of cytoskeleton,PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;,,,7.00E-32,ruditapes_c20852,,,,,TLN1_HUMAN,Homo sapiens (Human),cell-cell junction assembly [GO:0007043]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; IRE1-mediated unfolded protein response [GO:0036498]; movement of cell or subcellular component [GO:0006928]; muscle contraction [GO:0006936]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; viral process [GO:0016032] comp144463_c0_seq3,1255,39.6813,1.0884245,49,73,,5.00E-10,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp144466_c0_seq1,2100,29.3333,0.93636414,196,1028,,7.00E-15,P21329,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROFU,Drosophila funebris (Fruit fly), comp144467_c0_seq1,2723,47.4477,0.50495457,526,197,,3.00E-165,Q8TEX9,Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4),Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4),GO:0005737; GO:0006886; GO:0005634; GO:0015031,cytoplasm; intracellular protein transport; nucleus; protein transport,PF02985;PF03810;,1.00E-59,CHOYP_BRAFLDRAFT_228853.1.1,,,,,,,IPO4_HUMAN,Homo sapiens (Human),"DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein transport [GO:0015031]; ribosomal protein import into nucleus [GO:0006610]" comp144467_c0_seq3,763,46.1337,0.51836863,44,17,,2.00E-27,Q8TEX9,Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4),Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4),GO:0005737; GO:0006886; GO:0005634; GO:0015031,cytoplasm; intracellular protein transport; nucleus; protein transport,PF02985;PF03810;,,,,,,,,,IPO4_HUMAN,Homo sapiens (Human),"DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein transport [GO:0015031]; ribosomal protein import into nucleus [GO:0006610]" comp144467_c0_seq5,1231,37.5305,0.44345961,0,0,,6.00E-06,Q8BIV3,Ran-binding protein 6 (RanBP6),Ran-binding protein 6 (RanBP6),GO:0005737; GO:0005634; GO:0015031,cytoplasm; nucleus; protein transport,PF02985;,,,,,,,,,RNBP6_MOUSE,Mus musculus (Mouse),"NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]" comp144468_c0_seq1,5930,40.4722,0.58631745,51,50,,1.00E-77,Q13813,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)",GO:0030018; GO:0003779; GO:0051693; GO:0007411; GO:0005509; GO:0006921; GO:0032437; GO:0005829; GO:0005916; GO:0043231; GO:0016328; GO:0016020; GO:0015630; GO:0008091; GO:0005200,Z disc; actin binding; actin filament capping; axon guidance; calcium ion binding; cellular component disassembly involved in execution phase of apoptosis; cuticular plate; cytosol; fascia adherens; intracellular membrane-bounded organelle; lateral plasma membrane; membrane; microtubule cytoskeleton; spectrin; structural constituent of cytoskeleton,PF13499;PF08726;PF00018;PF00435;,0,CHOYP_LOC100743601.1.1,,,,,,,SPTN1_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; ER to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165] comp144468_c0_seq2,5919,40.4122,0.58530414,63,13,,0,Q00963,Spectrin beta chain,Spectrin beta chain,GO:0003779; GO:0051693; GO:0030506; GO:0016327; GO:0030424; GO:0016199; GO:0045169; GO:0045478; GO:0016328; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0005546; GO:0072499; GO:0007009; GO:0008091; GO:0045170; GO:0030721; GO:0005200,"actin binding; actin filament capping; ankyrin binding; apicolateral plasma membrane; axon; axon midline choice point recognition; fusome; fusome organization; lateral plasma membrane; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; phosphatidylinositol-4,5-bisphosphate binding; photoreceptor cell axon guidance; plasma membrane organization; spectrin; spectrosome; spectrosome organization; structural constituent of cytoskeleton",PF00307;PF00435;,,,9.00E-119,ruditapes_c21356,,,,,SPTCB_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721] comp144468_c0_seq3,5722,39.7938,0.5810461,42,12,,0,Q00963,Spectrin beta chain,Spectrin beta chain,GO:0003779; GO:0051693; GO:0030506; GO:0016327; GO:0030424; GO:0016199; GO:0045169; GO:0045478; GO:0016328; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0005546; GO:0072499; GO:0007009; GO:0008091; GO:0045170; GO:0030721; GO:0005200,"actin binding; actin filament capping; ankyrin binding; apicolateral plasma membrane; axon; axon midline choice point recognition; fusome; fusome organization; lateral plasma membrane; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; phosphatidylinositol-4,5-bisphosphate binding; photoreceptor cell axon guidance; plasma membrane organization; spectrin; spectrosome; spectrosome organization; structural constituent of cytoskeleton",PF00307;PF00435;,0,CHOYP_LOC100743601.1.1,,,,,,,SPTCB_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721] comp144468_c0_seq4,5736,39.8013,0.57914847,0,0,,5.00E-78,Q13813,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)",GO:0030018; GO:0003779; GO:0051693; GO:0007411; GO:0005509; GO:0006921; GO:0032437; GO:0005829; GO:0005916; GO:0043231; GO:0016328; GO:0016020; GO:0015630; GO:0008091; GO:0005200,Z disc; actin binding; actin filament capping; axon guidance; calcium ion binding; cellular component disassembly involved in execution phase of apoptosis; cuticular plate; cytosol; fascia adherens; intracellular membrane-bounded organelle; lateral plasma membrane; membrane; microtubule cytoskeleton; spectrin; structural constituent of cytoskeleton,PF13499;PF08726;PF00018;PF00435;,0,CHOYP_LOC100743601.1.1,2.00E-13,ruditapes_c30729,,,,,SPTN1_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; ER to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165] comp144468_c1_seq1,3667,47.8866,0.64068788,2575,929,,0,Q00963,Spectrin beta chain,Spectrin beta chain,GO:0003779; GO:0051693; GO:0030506; GO:0016327; GO:0030424; GO:0016199; GO:0045169; GO:0045478; GO:0016328; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0005546; GO:0072499; GO:0007009; GO:0008091; GO:0045170; GO:0030721; GO:0005200,"actin binding; actin filament capping; ankyrin binding; apicolateral plasma membrane; axon; axon midline choice point recognition; fusome; fusome organization; lateral plasma membrane; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; phosphatidylinositol-4,5-bisphosphate binding; photoreceptor cell axon guidance; plasma membrane organization; spectrin; spectrosome; spectrosome organization; structural constituent of cytoskeleton",PF00307;PF00435;,0,CHOYP_LOC100114310.2.2,,,,,,,SPTCB_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721] comp144469_c0_seq1,1538,31.9246,0.97714327,14,25,,,,,,,,,4.00E-11,CHOYP_LOC100561123.22.28,,,,,,,,, comp144469_c0_seq2,1551,31.7215,0.98040104,98,175,,2.00E-08,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,7.00E-14,CHOYP_LOC100561123.26.28,2.00E-18,ruditapes_c30227,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144469_c0_seq3,991,33.4006,1.1326715,9,3,,2.00E-06,Q10126,Putative uncharacterized transposon-derived protein F52C9.6,Putative uncharacterized transposon-derived protein F52C9.6,GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF00078;,,,,,,,,,YSM6_CAEEL,Caenorhabditis elegans, comp144469_c0_seq4,979,33.7079,1.16023651,0,0,,,,,,,,,2.00E-11,CHOYP_LOC100561123.22.28,,,,,,,,, comp144469_c1_seq2,370,29.7297,0.86308374,33,188,,,,,,,,,,,7.00E-11,ruditapes_c24062,,,,,,, comp144470_c0_seq1,2625,47.0476,0.46741107,85,352,,9.00E-98,P08775,DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit),DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit),GO:0003677; GO:0005665; GO:0003899; GO:0046872; GO:0006366,"DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; metal ion binding; transcription from RNA polymerase II promoter",PF04997;PF00623;PF04983;PF05000;PF04998;PF04992;PF04990;PF05001;,2.00E-86,CHOYP_BH13620.1.1,,,,,,,RPB1_MOUSE,Mus musculus (Mouse),"cellular response to oxygen levels [GO:0071453]; DNA-templated transcription, termination [GO:0006353]; piRNA metabolic process [GO:0034587]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription from RNA polymerase II promoter [GO:0006366]" comp144470_c0_seq2,2274,44.1513,0.53934225,409,589,,0,P24928,DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48),DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48),GO:0006370; GO:0003677; GO:0005665; GO:0003899; GO:0003968; GO:0000398; GO:0046872; GO:0050434; GO:0006355; GO:0006368; GO:0006367; GO:0006283; GO:0016032,"7-methylguanosine mRNA capping; DNA binding; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase activity; RNA-directed RNA polymerase activity; mRNA splicing, via spliceosome; metal ion binding; positive regulation of viral transcription; regulation of transcription, DNA-dependent; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; viral process",PF04997;PF00623;PF04983;PF05000;PF04998;PF04992;PF04990;PF05001;,0,CHOYP_RPB1.1.1,,,,,,,RPB1_HUMAN,Homo sapiens (Human),"7-methylguanosine mRNA capping [GO:0006370]; DNA-templated transcription, termination [GO:0006353]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA splicing [GO:0033120]; positive regulation of viral transcription [GO:0050434]; regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp144470_c0_seq3,2562,47.0336,0.46952512,24,184,,4.00E-29,O28390,DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6),DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6),GO:0003677; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF04998;,,,,,,,,,RPOA2_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126),"transcription, DNA-templated [GO:0006351]" comp144470_c0_seq4,1139,46.532,0.63368587,214,367,,3.00E-30,Q9V113,DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6),DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6),GO:0003677; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF04998;,0,CHOYP_RPB1.1.1,,,,,,,RPOA2_PYRAB,Pyrococcus abyssi (strain GE5 / Orsay),"transcription, DNA-templated [GO:0006351]" comp144472_c1_seq1,2457,38.9092,0.95815884,1100,103,,3.00E-67,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,1.00E-14,CHOYP_LOC100533355.1.2,,,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp144472_c1_seq3,1652,36.7433,1.07855971,314,0,male,8.00E-16,O61788,Innexin-17 (Gap junction innexin) (Protein opu-17),Innexin-17 (Gap junction innexin) (Protein opu-17),GO:0005921; GO:0055077; GO:0016021; GO:0006811; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transport; plasma membrane,PF00876;,2.00E-14,CHOYP_LOC100533354.6.6,,,,,,,INX17_CAEEL,Caenorhabditis elegans,ion transport [GO:0006811] comp144474_c0_seq1,2320,45.9914,0.39602447,0,0,,0,Q63170,"Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)","Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0005509; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; calcium ion binding; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,,,,,,,,,DYH7_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341] comp144474_c0_seq2,1120,45.0893,0.52822585,21,0,,1.00E-07,Q96M86,Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35),Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35),GO:0030031; GO:0001539; GO:0030286; GO:0003777; GO:0007018,cell projection assembly; ciliary or bacterial-type flagellar motility; dynein complex; microtubule motor activity; microtubule-based movement,PF08393;PF03028;PF12777;,4.00E-53,CHOYP_LOC587136.3.3,,,,,,,DNHD1_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144474_c0_seq3,2580,44.6124,0.50098577,0,0,,3.00E-32,Q8IID4,Dynein heavy chain-like protein PF11_0240,Dynein heavy chain-like protein PF11_0240,GO:0005524; GO:0006200; GO:0016887; GO:0005737; GO:0030286; GO:0005874; GO:0005875; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cytoplasm; dynein complex; microtubule; microtubule associated complex; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF00630;PF12777;,0,CHOYP_DNAH7.2.2,,,,,,,DYHC2_PLAF7,Plasmodium falciparum (isolate 3D7),microtubule-based movement [GO:0007018] comp144474_c0_seq4,1230,45.122,0.43447088,0,0,,,,,,,,,3.00E-93,CHOYP_LOC100378331.1.1,,,,,,,,, comp144474_c0_seq5,5772,42.377,0.50430735,1785,285,,0,Q63170,"Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)","Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0005509; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; calcium ion binding; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH12.2.3,,,,,,,DYH7_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341] comp144476_c2_seq1,4214,34.0769,0.86839655,2086,5300,,,,,,,,,,,7.00E-106,ruditapes2_c3594,,,,,,, comp144476_c2_seq2,7747,37.2144,0.63849426,2543,8922,,0,P22314,Ubiquitin-like modifier-activating enzyme 1 (Protein A1S9) (Ubiquitin-activating enzyme E1),Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1),GO:0005524; GO:0008219; GO:0016874; GO:0016567; GO:0008641,ATP binding; cell death; ligase activity; protein ubiquitination; small protein activating enzyme activity,PF16191;PF16190;PF09358;PF00899;PF10585;,0,CHOYP_UBA1.2.2,4.00E-105,ruditapes2_c3812,,,,,UBA1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; modification-dependent protein catabolic process [GO:0019941] comp144477_c0_seq2,9965,43.1109,0.66303569,0,0,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH6.3.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144477_c0_seq3,11404,43.8092,0.6535073,0,0,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH6.2.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144477_c0_seq4,9954,43.0681,0.66064753,0,0,,0,Q63164,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,5.00E-70,CHOYP_DYH1.1.1,,,,,,,DYH1_RAT,Rattus norvegicus (Rat),cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp144477_c0_seq5,11393,43.7725,0.65147851,0,0,,0,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH6.2.3,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144478_c0_seq1,2019,47.4492,0.57184071,93,33,,,,,,,,,2.00E-15,CHOYP_LOC100892567.7.8,,,,,,,,, comp144478_c0_seq2,1452,48.9669,0.64286894,31,14,,5.00E-28,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144478_c0_seq4,1440,48.6806,0.62040103,1,0,,9.00E-10,Q03277,Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment),GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF14529;PF00078;,8.00E-26,CHOYP_LOC100887947.1.2,,,,,,,PO11_SCICO,Bradysia coprophila (Dark-winged fungus gnat) (Sciara coprophila), comp144479_c0_seq1,5745,44.1601,0.57062288,208,171,,1.00E-44,Q6ZQQ6,WD repeat-containing protein 87 (Testis development protein NYD-SP11),WD repeat-containing protein 87 (Testis development protein NYD-SP11),,,PF00400;,,,,,,,,,WDR87_HUMAN,Homo sapiens (Human), comp144479_c0_seq2,4479,44.3626,0.53194563,0,0,,6.00E-45,Q6ZQQ6,WD repeat-containing protein 87 (Testis development protein NYD-SP11),WD repeat-containing protein 87 (Testis development protein NYD-SP11),,,PF00400;,,,,,,,,,WDR87_HUMAN,Homo sapiens (Human), comp144479_c0_seq3,5644,44.0468,0.57283365,325,35,,1.00E-07,Q09715,Transcriptional repressor tup11,Transcriptional repressor tup11,GO:0006342; GO:0005829; GO:0042393; GO:0045014; GO:0000122; GO:0000790; GO:0043234; GO:0003714; GO:0006351,"chromatin silencing; cytosol; histone binding; negative regulation of transcription by glucose; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein complex; transcription corepressor activity; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP11_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp144479_c0_seq4,4283,44.4081,0.52087724,41,42,,5.00E-45,Q6ZQQ6,WD repeat-containing protein 87 (Testis development protein NYD-SP11),WD repeat-containing protein 87 (Testis development protein NYD-SP11),,,PF00400;,,,,,,,,,WDR87_HUMAN,Homo sapiens (Human), comp144479_c0_seq7,4378,44.2668,0.53726595,0,0,,7.00E-08,Q09715,Transcriptional repressor tup11,Transcriptional repressor tup11,GO:0006342; GO:0005829; GO:0042393; GO:0045014; GO:0000122; GO:0000790; GO:0043234; GO:0003714; GO:0006351,"chromatin silencing; cytosol; histone binding; negative regulation of transcription by glucose; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein complex; transcription corepressor activity; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP11_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp144480_c0_seq1,1930,40.5181,0.34482152,498,11,,4.00E-10,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp144480_c0_seq2,2072,40.1544,0.29059566,69,5,,1.00E-41,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp144480_c0_seq3,1317,40.7745,0.24142609,29,0,,5.00E-32,P49013,Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III),GO:0005509; GO:0005615,calcium ion binding; extracellular space,PF01382;PF00431;PF00008;,,,,,,,,,FBP3_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp144480_c0_seq5,934,39.6146,0.33030154,29,0,,9.00E-07,Q8IX30,"Signal peptide, CUB and EGF-like domain-containing protein 3","Signal peptide, CUB and EGF-like domain-containing protein 3",GO:0005509; GO:0009986; GO:0005576; GO:0051291; GO:0051260,calcium ion binding; cell surface; extracellular region; protein heterooligomerization; protein homooligomerization,PF12662;PF00431;PF12947;PF07645;PF07699;,,,,,,,,,SCUB3_HUMAN,Homo sapiens (Human),protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] comp144480_c1_seq2,1861,40.1934,0.3896523,25,0,,4.00E-06,Q8CHN8,Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain],Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain],GO:0005509; GO:0001867; GO:0005615; GO:0006508; GO:0004252,"calcium ion binding; complement activation, lectin pathway; extracellular space; proteolysis; serine-type endopeptidase activity",PF00431;PF07645;PF00084;PF00089;,,,,,,,,,MASP1_RAT,Rattus norvegicus (Rat),"complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]" comp144482_c0_seq1,6567,37.8864,0.55806871,30,20,,2.00E-157,Q08999,Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2),Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2),GO:0003677; GO:0016568; GO:0005737; GO:0000278; GO:0005730; GO:0005654; GO:0051726; GO:0043550; GO:0006357; GO:0005667; GO:0006351,"DNA binding; chromatin modification; cytoplasm; mitotic cell cycle; nucleolus; nucleoplasm; regulation of cell cycle; regulation of lipid kinase activity; regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent",PF11934;PF01858;PF01857;,,,,,,,,,RBL2_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of gene expression [GO:0010629]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144482_c0_seq2,6506,37.8266,0.55641929,44,73,,0,Q08999,Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2),Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2),GO:0003677; GO:0016568; GO:0005737; GO:0000278; GO:0005730; GO:0005654; GO:0051726; GO:0043550; GO:0006357; GO:0005667; GO:0006351,"DNA binding; chromatin modification; cytoplasm; mitotic cell cycle; nucleolus; nucleoplasm; regulation of cell cycle; regulation of lipid kinase activity; regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent",PF11934;PF01858;PF01857;,2.00E-174,CHOYP_BRAFLDRAFT_218889.2.2,,,,,,,RBL2_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of gene expression [GO:0010629]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144483_c1_seq1,6918,41.9919,0.33197044,1796,615,,2.00E-70,Q7Z442,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005509; GO:0030246; GO:0016021; GO:0006811; GO:0007218,calcium ion binding; carbohydrate binding; integral to membrane; ion transport; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982] comp144483_c1_seq2,3539,43.2608,0.36871981,66,16,,4.00E-63,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp144483_c1_seq5,3682,39.924,0.37747965,412,19,,9.00E-24,Q14766,Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1),Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1),GO:0005509; GO:0030198; GO:0005578; GO:0035583; GO:0005024,calcium ion binding; extracellular matrix organization; proteinaceous extracellular matrix; sequestering of TGFbeta in extracellular matrix; transforming growth factor beta-activated receptor activity,PF12662;PF07645;PF00683;,,,,,,,,,LTBP1_HUMAN,Homo sapiens (Human),aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; ventricular septum development [GO:0003281] comp144484_c0_seq1,3576,35.8501,0.37434534,32,213,,3.00E-23,Q14978,Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130),Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130),GO:0005524; GO:0005525; GO:0005737; GO:0007067; GO:0005730; GO:0006364,ATP binding; GTP binding; cytoplasm; mitosis; nucleolus; rRNA processing,PF05022;,,,,,,,,,NOLC1_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; mitotic nuclear division [GO:0007067]; nucleolus organization [GO:0007000]; rRNA processing [GO:0006364] comp144484_c0_seq4,4508,34.827,0.40981331,44,311,,5.00E-23,Q14978,Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130),Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130),GO:0005524; GO:0005525; GO:0005737; GO:0007067; GO:0005730; GO:0006364,ATP binding; GTP binding; cytoplasm; mitosis; nucleolus; rRNA processing,PF05022;,,,,,,,,,NOLC1_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; mitotic nuclear division [GO:0007067]; nucleolus organization [GO:0007000]; rRNA processing [GO:0006364] comp144485_c0_seq1,942,43.4183,0.50454846,0,0,,5.00E-09,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp144485_c0_seq7,696,47.5575,0.56666784,67,252,,5.00E-08,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144486_c0_seq1,4194,36.8383,0.63565644,8,5,,9.00E-71,P42669,Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),GO:0005662; GO:0006268; GO:0046332; GO:0006915; GO:0030154; GO:0008283; GO:0005737; GO:0030425; GO:0003690; GO:0003691; GO:0007093; GO:0045892; GO:0007399; GO:0043025; GO:0008284; GO:0032422; GO:0003700; GO:0003697; GO:0006351; GO:0000900,"DNA replication factor A complex; DNA unwinding involved in DNA replication; SMAD binding; apoptotic process; cell differentiation; cell proliferation; cytoplasm; dendrite; double-stranded DNA binding; double-stranded telomeric DNA binding; mitotic cell cycle checkpoint; negative regulation of transcription, DNA-dependent; nervous system development; neuronal cell body; positive regulation of cell proliferation; purine-rich negative regulatory element binding; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription, DNA-dependent; translation repressor activity, nucleic acid binding",PF04845;,,,,,,,,,PURA_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]" comp144486_c0_seq2,4094,37.0054,0.64603341,0,0,,,,,,,,,,,4.00E-153,ruditapes_c12121,,,,,,, comp144486_c0_seq3,2621,38.6112,0.68204663,347,103,,7.00E-55,Q9UJV8,Purine-rich element-binding protein gamma,Purine-rich element-binding protein gamma,GO:0003677; GO:0005634,DNA binding; nucleus,PF04845;,7.00E-118,CHOYP_ISCW_ISCW005651.1.1,2.00E-180,ruditapes_c8146,,,,,PURG_HUMAN,Homo sapiens (Human), comp144486_c0_seq4,4180,36.7943,0.63905683,0,0,,9.00E-71,P42669,Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),GO:0005662; GO:0006268; GO:0046332; GO:0006915; GO:0030154; GO:0008283; GO:0005737; GO:0030425; GO:0003690; GO:0003691; GO:0007093; GO:0045892; GO:0007399; GO:0043025; GO:0008284; GO:0032422; GO:0003700; GO:0003697; GO:0006351; GO:0000900,"DNA replication factor A complex; DNA unwinding involved in DNA replication; SMAD binding; apoptotic process; cell differentiation; cell proliferation; cytoplasm; dendrite; double-stranded DNA binding; double-stranded telomeric DNA binding; mitotic cell cycle checkpoint; negative regulation of transcription, DNA-dependent; nervous system development; neuronal cell body; positive regulation of cell proliferation; purine-rich negative regulatory element binding; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription, DNA-dependent; translation repressor activity, nucleic acid binding",PF04845;,,,,,,,,,PURA_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]" comp144486_c0_seq5,4114,36.9713,0.64393148,0,0,,,,,,,,,1.00E-117,CHOYP_ISCW_ISCW005651.1.1,,,,,,,,, comp144486_c0_seq6,4214,36.8059,0.63362024,0,0,,9.00E-54,Q9UJV8,Purine-rich element-binding protein gamma,Purine-rich element-binding protein gamma,GO:0003677; GO:0005634,DNA binding; nucleus,PF04845;,,,,,,,,,PURG_HUMAN,Homo sapiens (Human), comp144486_c0_seq7,3670,37.4114,0.64710457,0,0,,4.00E-71,P42669,Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),GO:0005662; GO:0006268; GO:0046332; GO:0006915; GO:0030154; GO:0008283; GO:0005737; GO:0030425; GO:0003690; GO:0003691; GO:0007093; GO:0045892; GO:0007399; GO:0043025; GO:0008284; GO:0032422; GO:0003700; GO:0003697; GO:0006351; GO:0000900,"DNA replication factor A complex; DNA unwinding involved in DNA replication; SMAD binding; apoptotic process; cell differentiation; cell proliferation; cytoplasm; dendrite; double-stranded DNA binding; double-stranded telomeric DNA binding; mitotic cell cycle checkpoint; negative regulation of transcription, DNA-dependent; nervous system development; neuronal cell body; positive regulation of cell proliferation; purine-rich negative regulatory element binding; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription, DNA-dependent; translation repressor activity, nucleic acid binding",PF04845;,,,,,,,,,PURA_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]" comp144486_c0_seq8,2608,38.5736,0.6860008,0,0,,7.00E-55,Q9UJV8,Purine-rich element-binding protein gamma,Purine-rich element-binding protein gamma,GO:0003677; GO:0005634,DNA binding; nucleus,PF04845;,7.00E-118,CHOYP_ISCW_ISCW005651.1.1,,,,,,,PURG_HUMAN,Homo sapiens (Human), comp144486_c0_seq9,4080,36.9608,0.64954579,0,0,,8.00E-71,P42669,Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha),GO:0005662; GO:0006268; GO:0046332; GO:0006915; GO:0030154; GO:0008283; GO:0005737; GO:0030425; GO:0003690; GO:0003691; GO:0007093; GO:0045892; GO:0007399; GO:0043025; GO:0008284; GO:0032422; GO:0003700; GO:0003697; GO:0006351; GO:0000900,"DNA replication factor A complex; DNA unwinding involved in DNA replication; SMAD binding; apoptotic process; cell differentiation; cell proliferation; cytoplasm; dendrite; double-stranded DNA binding; double-stranded telomeric DNA binding; mitotic cell cycle checkpoint; negative regulation of transcription, DNA-dependent; nervous system development; neuronal cell body; positive regulation of cell proliferation; purine-rich negative regulatory element binding; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription, DNA-dependent; translation repressor activity, nucleic acid binding",PF04845;,,,,,,,,,PURA_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]" comp144487_c0_seq1,4543,39.2912,0.46206923,194,441,,3.00E-123,Q15459,Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114),Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114),GO:0003723; GO:0005684; GO:0071013; GO:0000389; GO:0005654,RNA binding; U2-type spliceosomal complex; catalytic step 2 spliceosome; mRNA 3'-splice site recognition; nucleoplasm,PF12230;PF01805;PF00240;,6.00E-65,CHOYP_SF3A1.2.3,,,,,,,SF3A1_HUMAN,Homo sapiens (Human),"mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp144487_c0_seq2,4616,39.5364,0.44914827,251,601,,8.00E-123,Q15459,Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114),Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114),GO:0003723; GO:0005684; GO:0071013; GO:0000389; GO:0005654,RNA binding; U2-type spliceosomal complex; catalytic step 2 spliceosome; mRNA 3'-splice site recognition; nucleoplasm,PF12230;PF01805;PF00240;,0,CHOYP_SF3A1.1.3,,,,,,,SF3A1_HUMAN,Homo sapiens (Human),"mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" comp144489_c0_seq1,14490,40.1656,0.42354375,11361,25114,,6.00E-98,Q9U943,Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)],GO:0016055; GO:0005576; GO:0008289; GO:0005319,Wnt receptor signaling pathway; extracellular region; lipid binding; lipid transporter activity,PF08742;PF06448;PF09172;PF01347;PF00094;,1.00E-16,CHOYP_PHUM_PHUM009400.1.1,,,,,,,APLP_LOCMI,Locusta migratoria (Migratory locust),Wnt signaling pathway [GO:0016055] comp144490_c1_seq13,3147,32.5071,1.07604515,0,0,,6.00E-25,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp144490_c1_seq2,3032,32.7177,1.06467978,0,0,,1.00E-25,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp144490_c1_seq4,3790,33.3509,1.05737324,0,0,,6.00E-25,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp144492_c0_seq1,3868,39.3485,0.45753144,57,175,,0,Q9EPU4,Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),GO:0003730; GO:0006379; GO:0005847; GO:0006378,mRNA 3'-UTR binding; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation,PF03178;,3.00E-143,CHOYP_CPSF1.1.1,,,,,,,CPSF1_MOUSE,Mus musculus (Mouse),mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp144492_c0_seq4,3863,39.3735,0.45780558,86,170,,0,Q9EPU4,Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),GO:0003730; GO:0006379; GO:0005847; GO:0006378,mRNA 3'-UTR binding; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation,PF03178;,4.00E-142,CHOYP_CPSF1.1.1,,,,,,,CPSF1_MOUSE,Mus musculus (Mouse),mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp144492_c0_seq5,1717,39.8369,0.44321011,0,4,,2.00E-19,Q9M0V3,DNA damage-binding protein 1a (UV-damaged DNA-binding protein 1a) (DDB1a),DNA damage-binding protein 1a (UV-damaged DNA-binding protein 1a) (DDB1a),GO:0080008; GO:0003677; GO:0006281; GO:0005829; GO:0010100; GO:0045892; GO:0005634; GO:0016567; GO:0009585,"Cul4-RING ubiquitin ligase complex; DNA binding; DNA repair; cytosol; negative regulation of photomorphogenesis; negative regulation of transcription, DNA-dependent; nucleus; protein ubiquitination; red, far-red light phototransduction",PF03178;,,,1.00E-10,ruditapes_c12182,,,,,DDB1A_ARATH,Arabidopsis thaliana (Mouse-ear cress),"nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; red, far-red light phototransduction [GO:0009585]" comp144495_c0_seq1,1275,33.6471,0.77723682,80,344,,2.00E-13,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,,,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp144495_c0_seq7,589,34.4652,1.08941033,7,0,,6.00E-26,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp144496_c0_seq6,1395,30.5376,0.34319703,35,51,,1.00E-09,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,2.00E-12,ruditapes2_c2681,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144497_c0_seq1,6336,43.9236,0.60229865,993,95,,0,Q6ZU64,Coiled-coil domain-containing protein 108,Coiled-coil domain-containing protein 108,GO:0016021; GO:0005198,integral to membrane; structural molecule activity,,,,,,,,,,CC108_HUMAN,Homo sapiens (Human), comp144497_c0_seq2,5573,46.2767,0.6034035,73,5,,,,,,,,,0,CHOYP_LOC100373429.1.1,,,,,,,,, comp144498_c0_seq3,1998,35.5355,0.3650099,12,24,,2.00E-35,Q8QZZ7,EKC/KEOPS complex subunit Tprkb (TP53RK-binding protein),EKC/KEOPS complex subunit Tprkb (TP53RK-binding protein),GO:0005829; GO:0005634; GO:0019901,cytosol; nucleus; protein kinase binding,PF08617;,6.00E-42,CHOYP_LOC100227090.1.1,,,,,,,TPRKB_MOUSE,Mus musculus (Mouse),tRNA processing [GO:0008033] comp144500_c0_seq3,6926,36.8322,0.51620551,444,1959,,4.00E-143,Q15042,Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP),Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP),GO:0005097; GO:0043010; GO:0005813; GO:0005737; GO:0060325; GO:0021854; GO:0005634,Rab GTPase activator activity; camera-type eye development; centrosome; cytoplasm; face morphogenesis; hypothalamus development; nucleus,PF13890;,1.00E-68,CHOYP_RB3GP.1.2,,,,,,,RB3GP_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid particle organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of short-term neuronal synaptic plasticity [GO:0048172] comp144501_c0_seq10,1294,38.949,0.75720268,1,0,,1.00E-45,P39060,Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin],Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin],GO:0001525; GO:0005604; GO:0007155; GO:0005581; GO:0030574; GO:0005788; GO:0001886; GO:0022617; GO:0005615; GO:0046872; GO:0008285; GO:0009887; GO:0043065; GO:0030335; GO:0008284; GO:0005198; GO:0007601,angiogenesis; basement membrane; cell adhesion; collagen; collagen catabolic process; endoplasmic reticulum lumen; endothelial cell morphogenesis; extracellular matrix disassembly; extracellular space; metal ion binding; negative regulation of cell proliferation; organ morphogenesis; positive regulation of apoptotic process; positive regulation of cell migration; positive regulation of cell proliferation; structural molecule activity; visual perception,PF01391;PF06121;PF06482;PF01392;,,,,,,,,,COIA1_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell proliferation [GO:0008285]; organ morphogenesis [GO:0009887]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601] comp144501_c0_seq11,1380,39.7826,0.75275904,0,0,,3.00E-44,O35206,Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV)],Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV)],GO:0005604; GO:0007155; GO:0005581; GO:0005615; GO:0005198,basement membrane; cell adhesion; collagen; extracellular space; structural molecule activity,PF01391;PF06482;,,,,,,,,,COFA1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp144501_c0_seq2,5059,49.4169,0.48008377,10,44,,1.00E-07,A2VEC9,SCO-spondin,SCO-spondin,GO:0007155; GO:0005615; GO:0010466; GO:0030414,cell adhesion; extracellular space; negative regulation of peptidase activity; peptidase inhibitor activity,PF08742;PF00754;PF00057;PF01826;PF00090;PF00094;,,,,,,,,,SSPO_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp144501_c0_seq3,4929,49.4624,0.47799011,7,14,,3.00E-42,O35206,Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV)],Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV)],GO:0005604; GO:0007155; GO:0005581; GO:0005615; GO:0005198,basement membrane; cell adhesion; collagen; extracellular space; structural molecule activity,PF01391;PF06482;,,,,,,,,,COFA1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp144502_c0_seq1,6504,44.3419,0.48930727,718,314,,4.00E-157,Q14008,Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG),Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG),GO:0000086; GO:0050658; GO:0051301; GO:0005813; GO:0051297; GO:0005829; GO:0030951; GO:0007067; GO:0007051; GO:0000922,G2/M transition of mitotic cell cycle; RNA transport; cell division; centrosome; centrosome organization; cytosol; establishment or maintenance of microtubule cytoskeleton polarity; mitosis; spindle organization; spindle pole,PF12348;,5.00E-125,CHOYP_CKAP5.1.1,,,,,,,CKAP5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; RNA transport [GO:0050658]; sister chromatid cohesion [GO:0007062]; spindle organization [GO:0007051] comp144502_c0_seq3,2395,44.4676,0.46438192,18,10,,4.00E-168,Q14008,Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG),Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG),GO:0000086; GO:0050658; GO:0051301; GO:0005813; GO:0051297; GO:0005829; GO:0030951; GO:0007067; GO:0007051; GO:0000922,G2/M transition of mitotic cell cycle; RNA transport; cell division; centrosome; centrosome organization; cytosol; establishment or maintenance of microtubule cytoskeleton polarity; mitosis; spindle organization; spindle pole,PF12348;,6.00E-106,CHOYP_CKAP5.1.1,,,,,,,CKAP5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; centrosome organization [GO:0051297]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; RNA transport [GO:0050658]; sister chromatid cohesion [GO:0007062]; spindle organization [GO:0007051] comp144502_c0_seq5,1512,45.1058,0.45334552,2,0,,8.00E-28,Q09933,Phosphoprotein p93,Phosphoprotein p93,GO:0008608; GO:0000778; GO:0005829; GO:0005874; GO:0008017; GO:0000070; GO:0044732; GO:0090307,attachment of spindle microtubules to kinetochore; condensed nuclear chromosome kinetochore; cytosol; microtubule; microtubule binding; mitotic sister chromatid segregation; mitotic spindle pole body; spindle assembly involved in mitosis,,,,,,,,,,DIS1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),attachment of mitotic spindle microtubules to kinetochore [GO:0051315] comp144504_c0_seq1,5095,44.2198,0.3336773,82,80,,2.00E-46,Q9ERU9,E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2),E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2),GO:0046907; GO:0016874; GO:0051028; GO:0005739; GO:0033132; GO:0042405; GO:0031965; GO:0044615; GO:0003755; GO:0006457; GO:0000413; GO:0016925; GO:0015031; GO:0090526; GO:0008270,intracellular transport; ligase activity; mRNA transport; mitochondrion; negative regulation of glucokinase activity; nuclear inclusion body; nuclear membrane; nuclear pore nuclear basket; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; protein sumoylation; protein transport; regulation of gluconeogenesis involved in cellular glucose homeostasis; zinc ion binding,PF12185;PF00160;PF00638;PF00641;,1.00E-22,CHOYP_PHUM_PHUM477850.1.1,,,,,,,RBP2_MOUSE,Mus musculus (Mouse),mRNA transport [GO:0051028]; negative regulation of glucokinase activity [GO:0033132]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; response to amphetamine [GO:0001975] comp144504_c0_seq2,5528,43.9399,0.35704819,222,328,,3.00E-46,Q9ERU9,E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2),E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2),GO:0046907; GO:0016874; GO:0051028; GO:0005739; GO:0033132; GO:0042405; GO:0031965; GO:0044615; GO:0003755; GO:0006457; GO:0000413; GO:0016925; GO:0015031; GO:0090526; GO:0008270,intracellular transport; ligase activity; mRNA transport; mitochondrion; negative regulation of glucokinase activity; nuclear inclusion body; nuclear membrane; nuclear pore nuclear basket; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; protein sumoylation; protein transport; regulation of gluconeogenesis involved in cellular glucose homeostasis; zinc ion binding,PF12185;PF00160;PF00638;PF00641;,,,,,,,,,RBP2_MOUSE,Mus musculus (Mouse),mRNA transport [GO:0051028]; negative regulation of glucokinase activity [GO:0033132]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; response to amphetamine [GO:0001975] comp144504_c0_seq5,415,41.4458,0.34121866,58,42,,4.00E-11,P40517,Ran-specific GTPase-activating protein 2 (Ran-binding protein 2) (RANBP2),Ran-specific GTPase-activating protein 2 (Ran-binding protein 2) (RANBP2),GO:0005096; GO:0005829; GO:0005643; GO:0043547; GO:0006611; GO:0031938; GO:0000056,GTPase activator activity; cytosol; nuclear pore; positive regulation of GTPase activity; protein export from nucleus; regulation of chromatin silencing at telomere; ribosomal small subunit export from nucleus,PF00638;,6.00E-27,CHOYP_PHUM_PHUM477850.1.1,,,,,,,YRB2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611]; regulation of chromatin silencing at telomere [GO:0031938]; ribosomal small subunit export from nucleus [GO:0000056] comp144506_c0_seq1,4288,46.5718,0.37001216,233,152,,4.00E-135,Q5U249,Protein ELYS (Protein MEL-28) (xELYS),Protein ELYS (Protein MEL-28) (xELYS),GO:0003677; GO:0051028; GO:0005643; GO:0015031,DNA binding; mRNA transport; nuclear pore; protein transport,PF13934;PF16687;,2.00E-27,CHOYP_AHCTF1.1.1,,,,,,,ELYS_XENLA,Xenopus laevis (African clawed frog),mRNA transport [GO:0051028]; protein transport [GO:0015031] comp144506_c0_seq3,2844,46.4135,0.36636156,2,10,,3.00E-10,O94384,Uncharacterized protein ely5,Uncharacterized protein ely5,GO:0005829; GO:0005643,cytosol; nuclear pore,PF13934;,,,,,,,,,ELY5_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),nuclear pore complex assembly [GO:0051292] comp144506_c0_seq4,1090,42.2018,0.53626028,17,10,,,,,,,,,,,4.00E-13,ruditapes_c27702,,,,,,, comp144506_c0_seq8,2369,46.5597,0.35880025,5,0,,3.00E-96,Q8CJF7,Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1),Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1),GO:0003677; GO:0000785; GO:0000777; GO:0000910; GO:0005737; GO:0030097; GO:0051028; GO:0007067; GO:0016363; GO:0031965; GO:0051292; GO:0031080; GO:0005654; GO:0045893; GO:0015031; GO:0003700; GO:0006351,"DNA binding; chromatin; condensed chromosome kinetochore; cytokinesis; cytoplasm; hemopoiesis; mRNA transport; mitosis; nuclear matrix; nuclear membrane; nuclear pore complex assembly; nuclear pore outer ring; nucleoplasm; positive regulation of transcription, DNA-dependent; protein transport; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF13934;PF16687;,,,,,,,,,ELYS_MOUSE,Mus musculus (Mouse),"cytokinesis [GO:0000910]; hemopoiesis [GO:0030097]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144507_c0_seq1,4276,35.898,0.54785013,12,167,,5.00E-140,Q27245,Putative aminopeptidase W07G4.4 (EC 3.4.11.-),Putative aminopeptidase W07G4.4 (EC 3.4.11.-),GO:0004177; GO:0005737; GO:0030145; GO:0008235; GO:0006508,aminopeptidase activity; cytoplasm; manganese ion binding; metalloexopeptidase activity; proteolysis,PF00883;,6.00E-128,CHOYP_BRAFLDRAFT_130974.1.1,,,,,,,YH24_CAEEL,Caenorhabditis elegans, comp144507_c0_seq2,4294,35.9106,0.53792817,12,378,,7.00E-140,Q27245,Putative aminopeptidase W07G4.4 (EC 3.4.11.-),Putative aminopeptidase W07G4.4 (EC 3.4.11.-),GO:0004177; GO:0005737; GO:0030145; GO:0008235; GO:0006508,aminopeptidase activity; cytoplasm; manganese ion binding; metalloexopeptidase activity; proteolysis,PF00883;,3.00E-126,CHOYP_BRAFLDRAFT_130974.1.1,7.00E-17,ruditapes2_lrc4111,,,,,YH24_CAEEL,Caenorhabditis elegans, comp144508_c0_seq1,3971,38.1012,0.21267104,0,0,,3.00E-09,Q9W735,Prominin-1-A (Prominin-like protein 1),Prominin-1-A (Prominin-like protein 1),GO:0016324; GO:0016021,apical plasma membrane; integral to membrane,PF05478;,,,,,,,,,PRM1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144508_c0_seq3,3990,37.8446,0.22107999,0,0,,4.00E-09,Q9W735,Prominin-1-A (Prominin-like protein 1),Prominin-1-A (Prominin-like protein 1),GO:0016324; GO:0016021,apical plasma membrane; integral to membrane,PF05478;,,,,,,,,,PRM1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144508_c0_seq6,3978,38.0845,0.21964011,0,0,,3.00E-09,Q9W735,Prominin-1-A (Prominin-like protein 1),Prominin-1-A (Prominin-like protein 1),GO:0016324; GO:0016021,apical plasma membrane; integral to membrane,PF05478;,,,,,,,,,PRM1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144509_c0_seq3,3543,36.8896,0.49199989,0,77,,4.00E-152,Q71RI9,Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III),Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III),GO:0006103; GO:0009058; GO:0047804; GO:0047315; GO:0016212; GO:0005739; GO:0030170,2-oxoglutarate metabolic process; biosynthetic process; cysteine-S-conjugate beta-lyase activity; kynurenine-glyoxylate transaminase activity; kynurenine-oxoglutarate transaminase activity; mitochondrion; pyridoxal phosphate binding,PF00155;,7.00E-88,CHOYP_KAT3.1.1,,,,,,,KAT3_MOUSE,Mus musculus (Mouse),2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189] comp144510_c0_seq4,671,43.5171,0.4468095,0,3,,,,,,,,,3.00E-27,CHOYP_LOC100371909.1.1,,,,,,,,, comp144510_c0_seq5,3520,37.1591,0.39064967,47,11,,4.00E-42,Q95K40,Coiled-coil domain-containing protein 83,Coiled-coil domain-containing protein 83,,,,,,,,,,,,CCD83_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp144511_c0_seq1,4574,45.9117,0.48983761,29,26,,,,,,,,,9.00E-12,CHOYP_LOC100184096.1.1,,,,,,,,, comp144511_c0_seq2,1268,41.0883,0.41790937,3,0,,8.00E-63,Q801E2,Actin-binding protein anillin,Actin-binding protein anillin,GO:0005938; GO:0051301; GO:0005856; GO:0007067; GO:0005634; GO:0005543,cell cortex; cell division; cytoskeleton; mitosis; nucleus; phospholipid binding,PF08174;PF16018;PF00169;,,,,,,,,,ANLN_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144511_c0_seq3,2376,43.9815,0.51835119,0,0,,1.00E-90,Q8K298,Actin-binding protein anillin,Actin-binding protein anillin,GO:0005826; GO:0000910; GO:0007067; GO:0005634; GO:0005543,actomyosin contractile ring; cytokinesis; mitosis; nucleus; phospholipid binding,PF08174;PF16018;PF00169;,0,CHOYP_ANLN.1.1,,,,,,,ANLN_MOUSE,Mus musculus (Mouse),glomerular visceral epithelial cell migration [GO:0090521]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067] comp144511_c0_seq4,2298,44.517,0.53221299,0,0,,5.00E-89,Q9NQW6,Actin-binding protein anillin,Actin-binding protein anillin,GO:0003779; GO:0005826; GO:0051301; GO:0007067; GO:0005634; GO:0005543; GO:0007096; GO:0000921,actin binding; actomyosin contractile ring; cell division; mitosis; nucleus; phospholipid binding; regulation of exit from mitosis; septin ring assembly,PF08174;PF16018;PF00169;,0,CHOYP_ANLN.1.1,,,,,,,ANLN_HUMAN,Homo sapiens (Human),glomerular visceral epithelial cell migration [GO:0090521]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of exit from mitosis [GO:0007096]; septin ring assembly [GO:0000921] comp144511_c0_seq6,3296,45.449,0.5297237,9,33,,2.00E-88,Q8K298,Actin-binding protein anillin,Actin-binding protein anillin,GO:0005826; GO:0000910; GO:0007067; GO:0005634; GO:0005543,actomyosin contractile ring; cytokinesis; mitosis; nucleus; phospholipid binding,PF08174;PF16018;PF00169;,,,,,,,,,ANLN_MOUSE,Mus musculus (Mouse),glomerular visceral epithelial cell migration [GO:0090521]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067] comp144511_c0_seq7,1190,42.0168,0.42666653,4,12,,4.00E-63,Q801E2,Actin-binding protein anillin,Actin-binding protein anillin,GO:0005938; GO:0051301; GO:0005856; GO:0007067; GO:0005634; GO:0005543,cell cortex; cell division; cytoskeleton; mitosis; nucleus; phospholipid binding,PF08174;PF16018;PF00169;,,,,,,,,,ANLN_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144511_c0_seq8,4493,46.183,0.4970389,0,0,,7.00E-77,Q9V4P1,Actin-binding protein anillin (Actin-binding protein 8) (ABP8) (Protein scraps),Actin-binding protein anillin (Actin-binding protein 8) (ABP8) (Protein scraps),GO:0003779; GO:0005826; GO:0051297; GO:0000915; GO:0032189; GO:0035323; GO:0030726; GO:0007112; GO:0007126; GO:0008017; GO:0007067; GO:0017022; GO:0022008; GO:0005634; GO:0048477; GO:0005543; GO:0007009; GO:0007279; GO:0051533; GO:0008104; GO:0045035; GO:0031106,"actin binding; actomyosin contractile ring; centrosome organization; cytokinesis, actomyosin contractile ring assembly; maintenance of actomyosin contractile ring localization; male germline ring canal; male germline ring canal formation; male meiosis cytokinesis; meiosis; microtubule binding; mitosis; myosin binding; neurogenesis; nucleus; oogenesis; phospholipid binding; plasma membrane organization; pole cell formation; positive regulation of NFAT protein import into nucleus; protein localization; sensory organ precursor cell division; septin ring organization",PF08174;PF16018;PF00169;,9.00E-12,CHOYP_LOC100184096.1.1,,,,,,,ANLN_DROME,Drosophila melanogaster (Fruit fly),actomyosin contractile ring assembly [GO:0000915]; asymmetric cell division [GO:0008356]; cellularization [GO:0007349]; centrosome organization [GO:0051297]; cytokinesis [GO:0000910]; intercellular bridge organization [GO:0043063]; maintenance of actomyosin contractile ring localization [GO:0032189]; male germline ring canal formation [GO:0030726]; male meiosis cytokinesis [GO:0007112]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; plasma membrane organization [GO:0007009]; pole cell formation [GO:0007279]; positive regulation of NFAT protein import into nucleus [GO:0051533]; protein localization [GO:0008104]; regulation of cytokinesis [GO:0032465]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; septin ring organization [GO:0031106] comp144511_c0_seq9,4613,45.8053,0.4879783,0,0,,,,,,,,,0,CHOYP_ANLN.1.1,,,2.00E-116,AM237648.p.cg.6,7,,,, comp144512_c0_seq1,3257,38.164,0.33088549,677,1179,,1.00E-46,Q68FS3,F-box only protein 7,F-box only protein 7,GO:0005737; GO:0005634; GO:0043234; GO:0016567; GO:0031647,cytoplasm; nucleus; protein complex; protein ubiquitination; regulation of protein stability,PF12937;PF11566;,,,,,,,,,FBX7_RAT,Rattus norvegicus (Rat),mitophagy [GO:0000422]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of lymphocyte differentiation [GO:0045620]; protein targeting to mitochondrion [GO:0006626]; protein ubiquitination [GO:0016567]; regulation of protein stability [GO:0031647] comp144513_c0_seq1,4756,39.3818,0.43982158,3,31,,1.00E-34,Q00808,Vegetative incompatibility protein HET-E-1,Vegetative incompatibility protein HET-E-1,GO:0005525,GTP binding,PF06985;PF00400;,0,CHOYP_COPB2.1.1,,,,,,,HETE1_PODAS,Podospora anserina (Pleurage anserina), comp144513_c0_seq2,3510,43.3333,0.39976145,0,24,,0,P35605,Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102),Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102),GO:0030126; GO:0006891; GO:0006886; GO:0005080; GO:0006890; GO:0005198,"COPI vesicle coat; intra-Golgi vesicle-mediated transport; intracellular protein transport; protein kinase C binding; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",PF04053;PF00400;,,,,,,,,,COPB2_BOVIN,Bos taurus (Bovine),"ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp144513_c0_seq3,4732,39.497,0.43961456,7,176,,0,Q9CAA0,Coatomer subunit beta'-1 (Beta'-coat protein 1) (Beta'-COP 1),Coatomer subunit beta'-1 (Beta'-coat protein 1) (Beta'-COP 1),GO:0030663; GO:0006886; GO:0030117; GO:0005198; GO:0016192,COPI-coated vesicle membrane; intracellular protein transport; membrane coat; structural molecule activity; vesicle-mediated transport,PF04053;PF00400;,,,,,,,,,COB21_ARATH,Arabidopsis thaliana (Mouse-ear cress),"ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp144513_c0_seq4,3536,43.241,0.3985843,0,0,,0,P35605,Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102),Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102),GO:0030126; GO:0006891; GO:0006886; GO:0005080; GO:0006890; GO:0005198,"COPI vesicle coat; intra-Golgi vesicle-mediated transport; intracellular protein transport; protein kinase C binding; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",PF04053;PF00400;,0,CHOYP_COPB2.1.1,,,,,,,COPB2_BOVIN,Bos taurus (Bovine),"ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp144514_c0_seq1,5612,44.9572,0.50900024,3133,91,,3.00E-77,A6NE52,WD repeat-containing protein KIAA1875,WD repeat-containing protein 97,,,PF00400;,5.00E-99,CHOYP_LOC100377114.1.1,,,,,,,K1875_HUMAN,Homo sapiens (Human),generation of catalytic spliceosome for second transesterification step [GO:0000350] comp144517_c0_seq1,2315,45.3132,0.41410876,7,0,,0,Q93008,"Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)","Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)",GO:0030509; GO:0045177; GO:0051301; GO:0007059; GO:0004197; GO:0005829; GO:0007292; GO:0007067; GO:0000122; GO:0016579; GO:0006367; GO:0007179; GO:0004221; GO:0006511,BMP signaling pathway; apical part of cell; cell division; chromosome segregation; cysteine-type endopeptidase activity; cytosol; female gamete generation; mitosis; negative regulation of transcription from RNA polymerase II promoter; protein deubiquitination; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,USP9X_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular protein metabolic process [GO:0044267]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144517_c0_seq3,5045,44.44,0.43750885,0,3,,2.00E-134,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,0,CHOYP_BRAFLDRAFT_275724.1.1,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144517_c0_seq4,6081,44.3841,0.45691916,423,113,,0,Q93008,"Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)","Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)",GO:0030509; GO:0045177; GO:0051301; GO:0007059; GO:0004197; GO:0005829; GO:0007292; GO:0007067; GO:0000122; GO:0016579; GO:0006367; GO:0007179; GO:0004221; GO:0006511,BMP signaling pathway; apical part of cell; cell division; chromosome segregation; cysteine-type endopeptidase activity; cytosol; female gamete generation; mitosis; negative regulation of transcription from RNA polymerase II promoter; protein deubiquitination; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,USP9X_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular protein metabolic process [GO:0044267]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144517_c1_seq1,2530,41.502,0.38760143,60,29,,0,P70398,"Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets homolog) (Fat facets protein-related, X-linked) (Ubiquitin carboxyl-terminal hydrolase FAM) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)","Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets homolog) (Fat facets protein-related, X-linked) (Ubiquitin carboxyl-terminal hydrolase FAM) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)",GO:0030509; GO:0045177; GO:0051301; GO:0007059; GO:0070410; GO:0008234; GO:0005737; GO:0007067; GO:0016579; GO:0007179; GO:0004221; GO:0006511,BMP signaling pathway; apical part of cell; cell division; chromosome segregation; co-SMAD binding; cysteine-type peptidase activity; cytoplasm; mitosis; protein deubiquitination; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,0,CHOYP_BRAFLDRAFT_275724.1.1,,,,,,,USP9X_MOUSE,Mus musculus (Mouse),axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cerebellar cortex structural organization [GO:0021698]; chromosome segregation [GO:0007059]; hippocampus development [GO:0021766]; in utero embryonic development [GO:0001701]; mitotic nuclear division [GO:0007067]; neuron migration [GO:0001764]; neuron projection extension [GO:1990138]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144517_c1_seq3,2454,41.4018,0.35386359,58,10,,4.00E-22,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144518_c0_seq1,7441,47.0232,0.65902084,18,21,,0,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,0,CHOYP_contig_044078,,,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp144518_c0_seq2,7414,47.0461,0.65582937,6,0,,0,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,0,CHOYP_contig_044078,,,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp144518_c0_seq3,4703,50.1807,0.64205101,0,0,,6.00E-31,Q502M6,Ankyrin repeat domain-containing protein 29,Ankyrin repeat domain-containing protein 29,,,PF00023;PF12796;,,,,,,,,,ANR29_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144518_c0_seq4,7554,46.8096,0.63269267,4,11,,0,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,0,CHOYP_contig_044078,,,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp144518_c0_seq5,4816,49.7301,0.611378,0,0,,7.00E-31,Q502M6,Ankyrin repeat domain-containing protein 29,Ankyrin repeat domain-containing protein 29,,,PF00023;PF12796;,,,,,,,,,ANR29_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144518_c0_seq6,3770,49.9735,0.59921973,7,14,,4.00E-40,Q9EQG6,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0030165; GO:0016482; GO:0005829; GO:0016021; GO:0005770; GO:0038180; GO:0010976; GO:0043234; GO:0019901; GO:0019887,PDZ domain binding; cytoplasmic transport; cytosol; integral to membrane; late endosome; nerve growth factor signaling pathway; positive regulation of neuron projection development; protein complex; protein kinase binding; protein kinase regulator activity,PF12796;PF07693;,,,,,,,,,KDIS_RAT,Rattus norvegicus (Rat),activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976] comp144518_c0_seq7,7581,46.8012,0.63318773,0,0,,0,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,0,CHOYP_contig_044078,,,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp144518_c0_seq8,7249,47.2203,0.65323596,0,0,,0,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,0,CHOYP_ANK3.6.9,5.00E-79,ruditapes_c25486,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp144519_c0_seq1,6493,46.604,0.41675635,2,0,,0,Q8BKX6,Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),GO:0005524; GO:0006281; GO:0005737; GO:0046872; GO:0000184; GO:0005634; GO:0018105; GO:0046854; GO:0046777; GO:0004674,"ATP binding; DNA repair; cytoplasm; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; phosphatidylinositol phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity",PF02260;PF00454;PF15785;,0,CHOYP_SMG1.1.1,,,,,,,SMG1_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]" comp144519_c0_seq3,3832,44.4154,0.44973184,2,0,,6.00E-96,Q5BKU6,Putative uncharacterized protein LOC641298,,,,,,,,,,,,,YP026_HUMAN,, comp144519_c0_seq5,6492,46.5958,0.41681896,22,18,,0,Q8BKX6,Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),GO:0005524; GO:0006281; GO:0005737; GO:0046872; GO:0000184; GO:0005634; GO:0018105; GO:0046854; GO:0046777; GO:0004674,"ATP binding; DNA repair; cytoplasm; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; phosphatidylinositol phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity",PF02260;PF00454;PF15785;,0,CHOYP_SMG1.1.1,,,,,,,SMG1_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]" comp144519_c0_seq7,3679,44.2783,0.44882978,0,0,,0,Q8BKX6,Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1),GO:0005524; GO:0006281; GO:0005737; GO:0046872; GO:0000184; GO:0005634; GO:0018105; GO:0046854; GO:0046777; GO:0004674,"ATP binding; DNA repair; cytoplasm; metal ion binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; peptidyl-serine phosphorylation; phosphatidylinositol phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity",PF02260;PF00454;PF15785;,,,,,,,,,SMG1_MOUSE,Mus musculus (Mouse),"DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]" comp144519_c0_seq8,1862,43.1257,0.51603414,0,0,,,,,,,,,1.00E-25,CHOYP_SMG1.1.1,,,,,,,,, comp144521_c0_seq2,509,36.7387,1.18798502,0,3,,,,,,,,,,,8.00E-12,ruditapes2_c2738,,,,,,, comp144521_c0_seq3,914,37.3085,0.78933842,1,0,,,,,,,,,,,4.00E-31,ruditapes_c20030,,,,,,, comp144521_c0_seq4,927,37.7562,0.85070817,47,102,,,,,,,,,,,2.00E-21,ruditapes_c16515,,,,,,, comp144523_c0_seq15,649,40.9861,0.30223844,3,5,,4.00E-06,A2AN08,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),GO:0005737; GO:0005856; GO:0016021; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144523_c0_seq2,541,41.22,0.17738565,0,0,,2.00E-06,A2AN08,E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600),GO:0005737; GO:0005856; GO:0016021; GO:0005634; GO:0042787; GO:0004842; GO:0008270,cytoplasm; cytoskeleton; integral to membrane; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF13764;PF02207;,,,,,,,,,UBR4_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp144525_c0_seq1,2963,48.7344,0.53352694,7,0,,2.00E-64,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp144525_c0_seq2,7733,48.5064,0.52987333,33,12,,9.00E-93,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,0,CHOYP_LOC100876515.2.2,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp144525_c0_seq3,10599,47.712,0.51290118,393,187,,6.00E-28,Q91ZU6,Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0016023; GO:0031122; GO:0005789; GO:0005925; GO:0030056; GO:0016021; GO:0014704; GO:0005882; GO:0045104; GO:0009898; GO:0046907; GO:0015630; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0097038; GO:0042803; GO:0031110; GO:0008090; GO:0042383; GO:0001725,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; endoplasmic reticulum membrane; focal adhesion; hemidesmosome; integral to membrane; intercalated disc; intermediate filament; intermediate filament cytoskeleton organization; internal side of plasma membrane; intracellular transport; microtubule cytoskeleton; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; retrograde axon cargo transport; sarcolemma; stress fiber,PF00307;PF13499;PF02187;PF00681;PF00435;,0,CHOYP_LOC100876515.2.2,,,,,,,DYST_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090] comp144525_c0_seq5,985,45.3807,0.62351662,97,72,,3.00E-23,Q6ZWR6,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005856; GO:0040023; GO:0016021; GO:0005635; GO:0005640; GO:0042803; GO:0030017,cytoskeleton; establishment of nucleus localization; integral to membrane; nuclear envelope; nuclear outer membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_MOUSE,Mus musculus (Mouse),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292] comp144526_c0_seq1,8830,41.1438,0.32123825,2931,607,,5.00E-46,P49790,Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153),Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153),GO:0003677; GO:0005975; GO:0019221; GO:0005737; GO:0015758; GO:0051028; GO:0007077; GO:0019048; GO:0046832; GO:0042405; GO:0031965; GO:0034399; GO:0051292; GO:0044615; GO:0005487; GO:0005730; GO:0005654; GO:0043495; GO:0015031; GO:0010827; GO:0044281; GO:0017056; GO:0055085; GO:0046718; GO:0075732; GO:0016032; GO:0008270,DNA binding; carbohydrate metabolic process; cytokine-mediated signaling pathway; cytoplasm; glucose transport; mRNA transport; mitotic nuclear envelope disassembly; modulation by virus of host morphology or physiology; negative regulation of RNA export from nucleus; nuclear inclusion body; nuclear membrane; nuclear periphery; nuclear pore complex assembly; nuclear pore nuclear basket; nucleocytoplasmic transporter activity; nucleolus; nucleoplasm; protein anchor; protein transport; regulation of glucose transport; small molecule metabolic process; structural constituent of nuclear pore; transmembrane transport; viral entry into host cell; viral penetration into host nucleus; viral process; zinc ion binding,PF08604;PF10599;PF00641;,,,,,,,,,NU153_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; negative regulation of RNA export from nucleus [GO:0046832]; nuclear pore complex assembly [GO:0051292]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]; viral process [GO:0016032]; viral transcription [GO:0019083] comp144527_c0_seq1,6273,40.7142,0.36416089,379,1306,,0,O60306,Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160),Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160),GO:0071013; GO:0000398; GO:0097157,"catalytic step 2 spliceosome; mRNA splicing, via spliceosome; pre-mRNA intronic binding",PF16399;,0,CHOYP_AQR.1.1,,,,,,,AQR_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp144528_c1_seq1,3547,46.7719,0.3823176,79,9,,9.00E-118,Q8BLA1,Deleted in lung and esophageal cancer protein 1 homolog,Deleted in lung and esophageal cancer protein 1 homolog,GO:0005737,cytoplasm,,2.00E-107,CHOYP_LOC100366606.1.2,,,,,,,DLEC1_MOUSE,Mus musculus (Mouse),negative regulation of cell proliferation [GO:0008285] comp144528_c1_seq2,3547,46.8565,0.37597843,94,0,,0,Q9Y238,Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1),Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1),GO:0005737; GO:0008285,cytoplasm; negative regulation of cell proliferation,,,,,,,,,,DLEC1_HUMAN,Homo sapiens (Human),negative regulation of cell proliferation [GO:0008285] comp144528_c2_seq1,3236,38.1644,0.42620598,1402,317,,,,,,,,,7.00E-12,CHOYP_SRC.1.2,,,,,,,,, comp144529_c0_seq1,1177,44.435,0.55990297,29,0,,,,,,,,,1.00E-110,CHOYP_RN213.7.13,1.00E-44,ruditapes_c17600,,,,,,, comp144529_c0_seq3,2399,45.7691,0.44773741,495,115,,2.00E-179,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,5.00E-75,CHOYP_RNF213.2.4,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144529_c0_seq4,863,42.0626,0.58862955,44,16,,,,,,,,,2.00E-61,CHOYP_RNF213.3.4,,,,,,,,, comp144531_c0_seq1,9602,41.8038,0.42386324,0,0,,4.00E-72,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,,,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq10,9569,41.7912,0.42320555,0,0,,7.00E-73,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,6.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq11,6027,42.9235,0.37831461,0,0,,7.00E-10,Q6C0K9,Transcription factor BYE1,Transcription factor BYE1,GO:0005634; GO:0006355; GO:0006351; GO:0008270,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF07744;PF07500;,4.00E-50,CHOYP_LOC100371354.1.1,,,,,,,BYE1_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq13,5964,42.8907,0.37560218,0,0,,1.00E-66,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,4.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq15,5967,42.8859,0.37916648,0,0,,2.00E-67,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,4.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq16,9628,41.8259,0.42216221,0,0,,3.00E-72,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,,,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq17,6009,42.919,0.37590649,0,0,,2.00E-41,Q9BTC0,Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1),Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1),GO:0006915; GO:0005737; GO:0005634; GO:0006351; GO:0008270,"apoptotic process; cytoplasm; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,4.00E-50,CHOYP_LOC100371354.1.1,,,,,,,DIDO1_HUMAN,Homo sapiens (Human),"apoptotic signaling pathway [GO:0097190]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq18,9630,41.8172,0.42477543,0,0,,4.00E-73,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,,,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq19,5994,42.9096,0.37702215,0,0,,3.00E-42,Q9BTC0,Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1),Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1),GO:0006915; GO:0005737; GO:0005634; GO:0006351; GO:0008270,"apoptotic process; cytoplasm; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,4.00E-24,CHOYP_ISCW_ISCW000551.1.1,,,,,,,DIDO1_HUMAN,Homo sapiens (Human),"apoptotic signaling pathway [GO:0097190]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq2,6012,42.9142,0.37943613,0,0,,1.00E-67,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,4.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq20,9586,41.8005,0.4247153,0,0,,7.00E-73,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,6.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq4,9613,41.808,0.42327477,0,0,,4.00E-73,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,6.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq5,9646,41.8204,0.42392881,0,0,,8.00E-11,Q148K0,Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2),Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2),GO:0003677; GO:0005634; GO:0032784; GO:0006357; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of DNA-dependent transcription, elongation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; zinc ion binding",PF08711;PF01096;PF07500;,6.00E-50,CHOYP_LOC100371354.1.1,,,,,,,TCEA2_BOVIN,Bos taurus (Bovine),"regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq6,5949,42.8475,0.37365675,5,7,,2.00E-67,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,4.00E-24,CHOYP_ISCW_ISCW000551.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144531_c0_seq7,5982,42.8954,0.37803409,0,0,,,,,,,,,4.00E-50,CHOYP_LOC100371354.1.1,,,,,,,,, comp144531_c0_seq8,9584,41.7988,0.42231171,0,0,,4.00E-72,Q92576,PHD finger protein 3,PHD finger protein 3,GO:0007275; GO:0005634; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; transcription, DNA-dependent; zinc ion binding",PF00628;PF07744;PF07500;,6.00E-50,CHOYP_LOC100371354.1.1,,,,,,,PHF3_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp144532_c0_seq1,1347,40.3118,0.61225535,100,181,,7.00E-157,Q07864,DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),GO:0051539; GO:0003677; GO:0006270; GO:0000731; GO:0003887; GO:0000082; GO:0006287; GO:0003682; GO:0008622; GO:0005654; GO:0000166; GO:0006297; GO:0000722; GO:0032201; GO:0006283; GO:0008270,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication initiation; DNA synthesis involved in DNA repair; DNA-directed DNA polymerase activity; G1/S transition of mitotic cell cycle; base-excision repair, gap-filling; chromatin binding; epsilon DNA polymerase complex; nucleoplasm; nucleotide binding; nucleotide-excision repair, DNA gap filling; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair; zinc ion binding",PF00136;PF03104;PF08490;,,,,,,,,,DPOE1_HUMAN,Homo sapiens (Human),"base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA synthesis involved in DNA repair [GO:0000731]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; nucleotide-excision repair, DNA gap filling [GO:0006297]; telomere maintenance via recombination [GO:0000722]" comp144532_c0_seq2,6194,43.7036,0.47412143,0,0,,0,Q6FNY7,DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),GO:0051539; GO:0003677; GO:0006260; GO:0003887; GO:0000166; GO:0005634; GO:0008270,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA-directed DNA polymerase activity; nucleotide binding; nucleus; zinc ion binding",PF00136;PF03104;PF08490;,0,CHOYP_DPOE1.1.1,,,,,,,DPOE_CANGA,Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata),DNA repair [GO:0006281]; DNA replication [GO:0006260] comp144532_c0_seq3,6159,43.9519,0.47112371,0,0,,0,Q9WVF7,DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),GO:0051539; GO:0003677; GO:0006260; GO:0000731; GO:0003887; GO:0000082; GO:0006287; GO:0003682; GO:0008622; GO:0000166; GO:0006297; GO:0008270,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA synthesis involved in DNA repair; DNA-directed DNA polymerase activity; G1/S transition of mitotic cell cycle; base-excision repair, gap-filling; chromatin binding; epsilon DNA polymerase complex; nucleotide binding; nucleotide-excision repair, DNA gap filling; zinc ion binding",PF00136;PF03104;PF08490;,0,CHOYP_DPOE1.1.1,,,,,,,DPOE1_MOUSE,Mus musculus (Mouse),"base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; nucleotide-excision repair, DNA gap filling [GO:0006297]" comp144532_c0_seq5,299,46.8227,0.2490171,16,44,,4.00E-49,Q9WVF7,DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A),GO:0051539; GO:0003677; GO:0006260; GO:0000731; GO:0003887; GO:0000082; GO:0006287; GO:0003682; GO:0008622; GO:0000166; GO:0006297; GO:0008270,"4 iron, 4 sulfur cluster binding; DNA binding; DNA replication; DNA synthesis involved in DNA repair; DNA-directed DNA polymerase activity; G1/S transition of mitotic cell cycle; base-excision repair, gap-filling; chromatin binding; epsilon DNA polymerase complex; nucleotide binding; nucleotide-excision repair, DNA gap filling; zinc ion binding",PF00136;PF03104;PF08490;,,,,,,,,,DPOE1_MOUSE,Mus musculus (Mouse),"base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; nucleotide-excision repair, DNA gap filling [GO:0006297]" comp144533_c0_seq1,5900,46.8136,0.52260882,0,0,,,,,,,,,0,CHOYP_ADGB.1.3,,,,,,,,, comp144533_c0_seq2,5752,46.8533,0.50960832,41,11,,1.00E-138,G3UZ78,Androglobin (Calpain-7-like protein),Androglobin (Calpain-7-like protein),GO:0004198; GO:0020037; GO:0005622; GO:0005506; GO:0019825; GO:0015671; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; heme binding; intracellular; iron ion binding; oxygen binding; oxygen transport; proteolysis,PF00648;,1.00E-175,CHOYP_ADGB.1.3,,,,,,,ADGB_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp144533_c0_seq3,5722,46.8717,0.51204482,0,0,,2.00E-138,G3UZ78,Androglobin (Calpain-7-like protein),Androglobin (Calpain-7-like protein),GO:0004198; GO:0020037; GO:0005622; GO:0005506; GO:0019825; GO:0015671; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; heme binding; intracellular; iron ion binding; oxygen binding; oxygen transport; proteolysis,PF00648;,3.00E-171,CHOYP_ADGB.2.3,,,,,,,ADGB_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp144533_c0_seq4,5930,46.7285,0.51865311,0,0,,,,,,,,,0,CHOYP_ADGB.1.3,,,,,,,,, comp144534_c0_seq1,8342,44.4857,0.45210633,6912,84,,0,Q8TD57,"Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b)","Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b)",GO:0005524; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,0,CHOYP_LOC100378331.1.1,,,,,,,DYH3_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144534_c0_seq2,1157,43.4745,0.60520776,1,6,,,,,,,,,0,CHOYP_LOC100378331.1.1,,,,,,,,, comp144535_c0_seq1,5398,38.8848,0.45196362,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq10,5703,38.7165,0.46920244,0,0,,2.00E-113,P0CO94,Pre-mRNA-splicing factor CEF1,Pre-mRNA-splicing factor CEF1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,,,,,,,,,CEF1_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq11,5718,38.6499,0.46954024,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq13,5764,38.6364,0.47524029,0,0,,1.00E-122,P92948,Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),GO:0003677; GO:0008380; GO:0007049; GO:0009507; GO:0003682; GO:0009870; GO:0010204; GO:0042742; GO:0050832; GO:0045087; GO:0006397; GO:0003700; GO:0005681; GO:0006351,"DNA binding; RNA splicing; cell cycle; chloroplast; chromatin binding; defense response signaling pathway, resistance gene-dependent; defense response signaling pathway, resistance gene-independent; defense response to bacterium; defense response to fungus; innate immune response; mRNA processing; sequence-specific DNA binding transcription factor activity; spliceosomal complex; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq14,4633,39.9309,0.45089238,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq15,4624,39.1652,0.44041276,0,0,,2.00E-87,Q52G60,Pre-mRNA-splicing factor CEF1,Pre-mRNA-splicing factor CEF1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,,,,,,,,,CEF1_MAGO7,Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq16,3344,42.9725,0.44151048,2,16,,2.00E-115,P92948,Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),GO:0003677; GO:0008380; GO:0007049; GO:0009507; GO:0003682; GO:0009870; GO:0010204; GO:0042742; GO:0050832; GO:0045087; GO:0006397; GO:0003700; GO:0005681; GO:0006351,"DNA binding; RNA splicing; cell cycle; chloroplast; chromatin binding; defense response signaling pathway, resistance gene-dependent; defense response signaling pathway, resistance gene-independent; defense response to bacterium; defense response to fungus; innate immune response; mRNA processing; sequence-specific DNA binding transcription factor activity; spliceosomal complex; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq17,3392,43.0425,0.44625951,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq18,5073,39.2864,0.45051257,0,0,,3.00E-126,Q4WHG0,Pre-mRNA-splicing factor cef1,Pre-mRNA-splicing factor cef1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CEF1_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq2,3618,43.0072,0.45021177,0,0,,,,,,,,,0,CHOYP_CDC5L.1.1,,,,,,,,, comp144535_c0_seq20,5459,38.7983,0.45843626,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq22,4905,39.4699,0.45116264,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq23,5426,38.7394,0.45298858,0,0,,0,A7SD85,Cell division cycle 5-related protein (Cdc5-like protein),Cell division cycle 5-related protein (Cdc5-like protein),GO:0003677; GO:0003723; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,,,,,,,,,CDC5L_NEMVE,Nematostella vectensis (Starlet sea anemone),cell cycle [GO:0007049]; DNA repair [GO:0006281]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq24,3681,41.7006,0.45656468,0,0,,0,O08837,Cell division cycle 5-like protein (Cdc5-like protein) (Pombe Cdc5-related protein),Cell division cycle 5-like protein (Cdc5-like protein) (Pombe Cdc5-related protein),GO:0003677; GO:0000086; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; G2/M transition of mitotic cell cycle; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_RAT,Rattus norvegicus (Rat),"cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-2 [GO:0071352]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to prolactin [GO:1990646]; cellular response to wortmannin [GO:1904568]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq25,2927,42.7058,0.4425726,0,0,,1.00E-64,P92948,Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),GO:0003677; GO:0008380; GO:0007049; GO:0009507; GO:0003682; GO:0009870; GO:0010204; GO:0042742; GO:0050832; GO:0045087; GO:0006397; GO:0003700; GO:0005681; GO:0006351,"DNA binding; RNA splicing; cell cycle; chloroplast; chromatin binding; defense response signaling pathway, resistance gene-dependent; defense response signaling pathway, resistance gene-independent; defense response to bacterium; defense response to fungus; innate immune response; mRNA processing; sequence-specific DNA binding transcription factor activity; spliceosomal complex; transcription, DNA-dependent",PF11831;,,,2.00E-34,ruditapes_c28817,,,,,CDC5L_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq26,2949,42.7603,0.44542426,0,0,,2.00E-44,Q7SAF6,Pre-mRNA-splicing factor cef-1,Pre-mRNA-splicing factor cef-1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,,,,,,,,,CEF1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq27,3420,42.6316,0.4448241,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq28,3642,41.7353,0.44818203,0,0,,8.00E-115,P92948,Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5),GO:0003677; GO:0008380; GO:0007049; GO:0009507; GO:0003682; GO:0009870; GO:0010204; GO:0042742; GO:0050832; GO:0045087; GO:0006397; GO:0003700; GO:0005681; GO:0006351,"DNA binding; RNA splicing; cell cycle; chloroplast; chromatin binding; defense response signaling pathway, resistance gene-dependent; defense response signaling pathway, resistance gene-independent; defense response to bacterium; defense response to fungus; innate immune response; mRNA processing; sequence-specific DNA binding transcription factor activity; spliceosomal complex; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_ARATH,Arabidopsis thaliana (Mouse-ear cress),"cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq29,3648,41.6393,0.44956518,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq3,5744,38.5272,0.4750764,0,0,,7.00E-126,Q4WHG0,Pre-mRNA-splicing factor cef1,Pre-mRNA-splicing factor cef1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CEF1_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq4,5439,38.6284,0.45448686,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq5,4467,40.1836,0.45581402,0,0,,2.00E-114,P0CO94,Pre-mRNA-splicing factor CEF1,Pre-mRNA-splicing factor CEF1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CEF1_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq6,5731,38.5797,0.47020222,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,,,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144535_c0_seq8,5413,38.814,0.45231468,0,0,,5.00E-126,Q4WHG0,Pre-mRNA-splicing factor cef1,Pre-mRNA-splicing factor cef1,GO:0003677; GO:0008380; GO:0007049; GO:0003682; GO:0005737; GO:0006397; GO:0005681,DNA binding; RNA splicing; cell cycle; chromatin binding; cytoplasm; mRNA processing; spliceosomal complex,PF11831;,0,CHOYP_CDC5L.1.1,,,,,,,CEF1_ASPFU,Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp144535_c0_seq9,5101,39.2668,0.4534604,0,0,,0,Q2KJC1,Cell division cycle 5-like protein (Cdc5-like protein),Cell division cycle 5-like protein (Cdc5-like protein),GO:0003677; GO:0000974; GO:0003723; GO:0071987; GO:0071013; GO:0007049; GO:0003682; GO:0005737; GO:0000398; GO:0016607; GO:0005730; GO:0006355; GO:0006351,"DNA binding; Prp19 complex; RNA binding; WD40-repeat domain binding; catalytic step 2 spliceosome; cell cycle; chromatin binding; cytoplasm; mRNA splicing, via spliceosome; nuclear speck; nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11831;,0,CHOYP_EF2.3.5,,,,,,,CDC5L_BOVIN,Bos taurus (Bovine),"cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]" comp144536_c0_seq1,6282,33.7791,0.43694011,0,0,,5.00E-92,Q80XI3,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0060903; GO:0001934; GO:0045727; GO:0007283; GO:0003743,positive regulation of meiosis I; positive regulation of protein phosphorylation; positive regulation of translation; spermatogenesis; translation initiation factor activity,PF02847;PF02854;PF02020;,,,,,,,,,IF4G3_MOUSE,Mus musculus (Mouse),positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283] comp144536_c0_seq10,4269,36.074,0.44716189,0,0,,7.00E-65,P41110,Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220),Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220),GO:0006417; GO:0003743,regulation of translation; translation initiation factor activity,PF02847;PF02854;PF02020;,1.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G1_RABIT,Oryctolagus cuniculus (Rabbit),regulation of translation [GO:0006417] comp144536_c0_seq11,3389,45.5001,0.45627611,0,0,,8.00E-100,Q6NZJ6,Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1),Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1),GO:0005737; GO:0006417; GO:0003743,cytoplasm; regulation of translation; translation initiation factor activity,PF02847;PF02854;PF02020;,4.00E-72,CHOYP_EIF4G3.1.1,,,,,,,IF4G1_MOUSE,Mus musculus (Mouse),behavioral fear response [GO:0001662]; positive regulation of neuron differentiation [GO:0045666]; regulation of translational initiation [GO:0006446] comp144536_c0_seq12,6279,33.8111,0.4360482,0,0,,2.00E-68,P41110,Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220),Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220),GO:0006417; GO:0003743,regulation of translation; translation initiation factor activity,PF02847;PF02854;PF02020;,2.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G1_RABIT,Oryctolagus cuniculus (Rabbit),regulation of translation [GO:0006417] comp144536_c0_seq13,3353,45.5115,0.46667117,0,0,,2.00E-105,Q6NZJ6,Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1),Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1),GO:0005737; GO:0006417; GO:0003743,cytoplasm; regulation of translation; translation initiation factor activity,PF02847;PF02854;PF02020;,9.00E-74,CHOYP_EIF4G3.1.1,,,,,,,IF4G1_MOUSE,Mus musculus (Mouse),behavioral fear response [GO:0001662]; positive regulation of neuron differentiation [GO:0045666]; regulation of translational initiation [GO:0006446] comp144536_c0_seq14,3389,45.5592,0.46643448,0,0,,,,,,,,,7.00E-18,CHOYP_NEMVEDRAFT_V1G217091.1.4,,,,,,,,, comp144536_c0_seq2,6265,33.759,0.43875004,0,0,,5.00E-92,Q80XI3,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0060903; GO:0001934; GO:0045727; GO:0007283; GO:0003743,positive regulation of meiosis I; positive regulation of protein phosphorylation; positive regulation of translation; spermatogenesis; translation initiation factor activity,PF02847;PF02854;PF02020;,2.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G3_MOUSE,Mus musculus (Mouse),positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283] comp144536_c0_seq3,4284,36.0411,0.44668371,0,0,,2.00E-89,O43432,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0000339; GO:0019221; GO:0005829; GO:0016281; GO:0019048; GO:0006446; GO:0008135; GO:0003743,"RNA cap binding; cytokine-mediated signaling pathway; cytosol; eukaryotic translation initiation factor 4F complex; modulation by virus of host morphology or physiology; regulation of translational initiation; translation factor activity, nucleic acid binding; translation initiation factor activity",PF02847;PF02854;PF02020;,1.00E-67,CHOYP_BRAFLDRAFT_277494.3.3,,,,,,,IF4G3_HUMAN,Homo sapiens (Human),regulation of translational initiation [GO:0006446]; viral process [GO:0016032] comp144536_c0_seq4,6266,33.7855,0.43776196,0,0,,5.00E-92,Q80XI3,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0060903; GO:0001934; GO:0045727; GO:0007283; GO:0003743,positive regulation of meiosis I; positive regulation of protein phosphorylation; positive regulation of translation; spermatogenesis; translation initiation factor activity,PF02847;PF02854;PF02020;,2.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G3_MOUSE,Mus musculus (Mouse),positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283] comp144536_c0_seq5,5205,35.1201,0.44944797,23,79,,1.00E-88,O43432,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0000339; GO:0019221; GO:0005829; GO:0016281; GO:0019048; GO:0006446; GO:0008135; GO:0003743,"RNA cap binding; cytokine-mediated signaling pathway; cytosol; eukaryotic translation initiation factor 4F complex; modulation by virus of host morphology or physiology; regulation of translational initiation; translation factor activity, nucleic acid binding; translation initiation factor activity",PF02847;PF02854;PF02020;,2.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G3_HUMAN,Homo sapiens (Human),regulation of translational initiation [GO:0006446]; viral process [GO:0016032] comp144536_c0_seq6,3353,45.4518,0.45638159,0,0,,7.00E-100,Q6NZJ6,Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1),Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1),GO:0005737; GO:0006417; GO:0003743,cytoplasm; regulation of translation; translation initiation factor activity,PF02847;PF02854;PF02020;,4.00E-72,CHOYP_EIF4G3.1.1,,,,,,,IF4G1_MOUSE,Mus musculus (Mouse),behavioral fear response [GO:0001662]; positive regulation of neuron differentiation [GO:0045666]; regulation of translational initiation [GO:0006446] comp144536_c0_seq7,6295,33.8046,0.43523174,0,0,,5.00E-92,Q80XI3,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0060903; GO:0001934; GO:0045727; GO:0007283; GO:0003743,positive regulation of meiosis I; positive regulation of protein phosphorylation; positive regulation of translation; spermatogenesis; translation initiation factor activity,PF02847;PF02854;PF02020;,,,,,,,,,IF4G3_MOUSE,Mus musculus (Mouse),positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283] comp144536_c0_seq8,6278,33.7846,0.43702704,0,0,,2.00E-68,P41110,Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220),Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220),GO:0006417; GO:0003743,regulation of translation; translation initiation factor activity,PF02847;PF02854;PF02020;,2.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G1_RABIT,Oryctolagus cuniculus (Rabbit),regulation of translation [GO:0006417] comp144536_c0_seq9,3970,36.5743,0.45893811,0,0,,2.00E-93,Q80XI3,Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII),GO:0060903; GO:0001934; GO:0045727; GO:0007283; GO:0003743,positive regulation of meiosis I; positive regulation of protein phosphorylation; positive regulation of translation; spermatogenesis; translation initiation factor activity,PF02847;PF02854;PF02020;,1.00E-78,CHOYP_BRAFLDRAFT_277494.1.3,,,,,,,IF4G3_MOUSE,Mus musculus (Mouse),positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283] comp144537_c1_seq1,1953,31.0292,0.51160216,202,610,,,,,,,,,,,2.00E-14,ruditapes_c19336,,,,,,, comp144540_c0_seq3,6699,44.2156,0.37239714,736,1812,,0,Q8QGX4,DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),GO:0005524; GO:0003677; GO:0004677; GO:0000724; GO:0006303; GO:0070419; GO:0005730; GO:0005654,ATP binding; DNA binding; DNA-dependent protein kinase activity; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end joining; nonhomologous end joining complex; nucleolus; nucleoplasm,PF02259;PF02260;PF08163;PF00454;,3.00E-103,CHOYP_PRKDC.1.1,,,,,,,PRKDC_CHICK,Gallus gallus (Chicken),DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431] comp144540_c0_seq4,206,49.0291,0.16428959,0,0,,2.00E-13,P78527,DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460),DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460),GO:0005524; GO:0002326; GO:0003677; GO:0004677; GO:0005958; GO:0033077; GO:0002360; GO:0033153; GO:0006915; GO:0007420; GO:0032869; GO:0005829; GO:0006303; GO:0035234; GO:0007507; GO:0033152; GO:0045087; GO:0005730; GO:0005654; GO:0018105; GO:0043065; GO:0045944; GO:0032481; GO:0002328; GO:0031648; GO:0010332; GO:0001756; GO:0000723; GO:0005667,ATP binding; B cell lineage commitment; DNA binding; DNA-dependent protein kinase activity; DNA-dependent protein kinase-DNA ligase 4 complex; T cell differentiation in thymus; T cell lineage commitment; T cell receptor V(D)J recombination; apoptotic process; brain development; cellular response to insulin stimulus; cytosol; double-strand break repair via nonhomologous end joining; germ cell programmed cell death; heart development; immunoglobulin V(D)J recombination; innate immune response; nucleolus; nucleoplasm; peptidyl-serine phosphorylation; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of type I interferon production; pro-B cell differentiation; protein destabilization; response to gamma radiation; somitogenesis; telomere maintenance; transcription factor complex,PF02259;PF02260;PF08163;PF00454;,3.00E-14,CHOYP_PRKDC.1.1,,,,,,,PRKDC_HUMAN,Homo sapiens (Human),B cell lineage commitment [GO:0002326]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to insulin stimulus [GO:0032869]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; ectopic germ cell programmed cell death [GO:0035234]; heart development [GO:0007507]; immunoglobulin V(D)J recombination [GO:0033152]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of response to gamma radiation [GO:2001229]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of developmental growth [GO:0048639]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune system process [GO:0002684]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; pro-B cell differentiation [GO:0002328]; protein destabilization [GO:0031648]; regulation of circadian rhythm [GO:0042752]; regulation of smooth muscle cell proliferation [GO:0048660]; response to activity [GO:0014823]; response to gamma radiation [GO:0010332]; rhythmic process [GO:0048511]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]; somitogenesis [GO:0001756]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell receptor V(D)J recombination [GO:0033153]; telomere capping [GO:0016233]; thymus development [GO:0048538] comp144541_c0_seq1,4434,41.6554,0.58336112,1078,2735,,4.00E-06,Q10411,Sporulation-specific protein 15,Sporulation-specific protein 15,GO:0031322; GO:0034613; GO:0005737; GO:0035974; GO:0044732,ascospore-type prospore-specific spindle pole body remodeling; cellular protein localization; cytoplasm; meiotic spindle pole body; mitotic spindle pole body,,3.00E-12,CHOYP_LOC100377654.1.1,,,,,,,SPO15_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),ascospore formation [GO:0030437]; ascospore-type prospore-specific spindle pole body remodeling [GO:0031322]; cellular protein localization [GO:0034613] comp144542_c0_seq11,2805,40.2139,0.45162233,0,0,,,,,,,,,6.00E-50,CHOYP_HFM1.1.1,,,,,,,,, comp144542_c0_seq12,1834,42.0938,0.41914128,0,0,,,,,,,,,4.00E-50,CHOYP_HFM1.1.1,,,,,,,,, comp144542_c0_seq14,456,41.6667,0.30436377,0,0,,3.00E-13,Q09475,Uncharacterized helicase C28H8.3 (EC 3.6.4.-),Uncharacterized helicase C28H8.3 (EC 3.6.4.-),GO:0005524; GO:0008026; GO:0003676; GO:0005634,ATP binding; ATP-dependent helicase activity; nucleic acid binding; nucleus,PF00270;PF00271;,,,,,,,,,YP93_CAEEL,Caenorhabditis elegans, comp144542_c0_seq3,2884,40.1872,0.45642199,7,0,,8.00E-145,A2RUV5,Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12),Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF00271;PF02889;,,,,,,,,,HFM1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),meiotic cell cycle [GO:0051321] comp144542_c0_seq5,2056,41.5856,0.42796458,0,0,,7.00E-148,A2RUV5,Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12),Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF00271;PF02889;,9.00E-65,CHOYP_HFM1.1.1,,,,,,,HFM1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),meiotic cell cycle [GO:0051321] comp144542_c0_seq6,4039,38.8958,0.46705357,92,27,,1.00E-24,P51979,ATP-dependent DNA helicase MER3 (EC 3.6.4.12) (Protein HFM1),ATP-dependent DNA helicase MER3 (EC 3.6.4.12) (Protein HFM1),GO:0005524; GO:0008026; GO:0003677; GO:0003678; GO:0006268; GO:0046872; GO:0005634; GO:0007131; GO:0007129,ATP binding; ATP-dependent helicase activity; DNA binding; DNA helicase activity; DNA unwinding involved in DNA replication; metal ion binding; nucleus; reciprocal meiotic recombination; synapsis,PF00270;PF00271;PF02889;,,,,,,,,,HFM1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),DNA unwinding involved in DNA replication [GO:0006268]; meiotic nuclear division [GO:0007126]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129] comp144542_c0_seq8,3756,39.0575,0.46343536,25,0,,2.00E-20,Q8N3C0,"Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)","Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)",GO:0005524; GO:0043140; GO:0006307; GO:0008283; GO:0005737; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA dealkylation involved in DNA repair; cell proliferation; cytoplasm; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00270;PF00271;PF02889;,,,,,,,,,ASCC3_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144542_c0_seq9,2082,41.6907,0.31113442,0,0,,2.00E-171,A2RUV5,Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12),Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12),GO:0005524; GO:0008026; GO:0003676,ATP binding; ATP-dependent helicase activity; nucleic acid binding,PF00270;PF00271;PF02889;,1.00E-68,CHOYP_HFM1.1.1,,,,,,,HFM1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),meiotic cell cycle [GO:0051321] comp144543_c0_seq1,4714,42.448,0.49082618,1127,6382,,0,P53621,Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin],Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin],GO:0048205; GO:0030126; GO:0005829; GO:0005615; GO:0006886; GO:0030157; GO:0006890; GO:0005198,"COPI coating of Golgi vesicle; COPI vesicle coat; cytosol; extracellular space; intracellular protein transport; pancreatic juice secretion; retrograde vesicle-mediated transport, Golgi to ER; structural molecule activity",PF12894;PF04053;PF06957;PF00400;,0,CHOYP_COPA.1.1,,,,,,,COPA_HUMAN,Homo sapiens (Human),"ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; pancreatic juice secretion [GO:0030157]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp144544_c0_seq1,4699,44.5201,0.47977181,1,21,,1.00E-134,O60318,Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase),Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase),GO:0003677; GO:0006260; GO:0005737; GO:0005829; GO:0005634; GO:0006606,DNA binding; DNA replication; cytoplasm; cytosol; nucleus; protein import into nucleus,PF16766;PF16769;PF16768;PF03399;,2.00E-57,CHOYP_MCM3AP.1.1,,,,,,,MCM3A_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606] comp144544_c0_seq2,6034,45.0282,0.48270387,4,0,,2.00E-31,A6NKF1,SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1),SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1),GO:0051301; GO:0005813; GO:0051298; GO:0005737; GO:0007067; GO:0005819; GO:0051225,cell division; centrosome; centrosome duplication; cytoplasm; mitosis; spindle; spindle assembly,PF03399;,,,,,,,,,SAC31_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144544_c0_seq3,6911,44.0891,0.52137273,7,14,,2.00E-132,O60318,Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase),Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase),GO:0003677; GO:0006260; GO:0005737; GO:0005829; GO:0005634; GO:0006606,DNA binding; DNA replication; cytoplasm; cytosol; nucleus; protein import into nucleus,PF16766;PF16769;PF16768;PF03399;,6.00E-61,CHOYP_MCM3AP.1.1,,,,,,,MCM3A_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606] comp144544_c0_seq4,6927,44.0883,0.51726306,6,165,,2.00E-31,A6NKF1,SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1),SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1),GO:0051301; GO:0005813; GO:0051298; GO:0005737; GO:0007067; GO:0005819; GO:0051225,cell division; centrosome; centrosome duplication; cytoplasm; mitosis; spindle; spindle assembly,PF03399;,4.00E-57,CHOYP_MCM3AP.1.1,,,,,,,SAC31_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp144544_c0_seq8,3535,45.4314,0.49640615,0,0,,2.00E-137,O60318,Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase),Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase),GO:0003677; GO:0006260; GO:0005737; GO:0005829; GO:0005634; GO:0006606,DNA binding; DNA replication; cytoplasm; cytosol; nucleus; protein import into nucleus,PF16766;PF16769;PF16768;PF03399;,,,,,,,,,MCM3A_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606] comp144544_c0_seq9,3479,45.4441,0.50986306,0,0,,2.00E-135,Q9WUU9,Germinal-center associated nuclear protein (GANP) (GC-associated DNA primase),Germinal-center associated nuclear protein (GANP) (GC-associated DNA primase),GO:0005737; GO:0005829; GO:0005634,cytoplasm; cytosol; nucleus,PF16766;PF16769;PF16768;PF03399;,2.00E-57,CHOYP_MCM3AP.1.1,,,,,,,MCM3A_MOUSE,Mus musculus (Mouse),immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein transport [GO:0015031] comp144546_c0_seq1,537,47.6723,0.53175376,149,11,,3.00E-11,Q54FZ8,Putative uncharacterized transmembrane protein DDB_G0290641,Putative uncharacterized transmembrane protein DDB_G0290641,,,,6.00E-111,CHOYP_LOC100030710.4.4,,,,,,,Y8923_DICDI,Dictyostelium discoideum (Slime mold), comp144546_c2_seq1,1140,44.2982,0.47088925,76,38,,2.00E-97,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144546_c2_seq3,824,43.0825,0.52631656,68,0,,,,,,,,,4.00E-52,CHOYP_RN213.13.13,,,,,,,,, comp144546_c2_seq5,726,42.4242,0.40182899,9,0,,3.00E-25,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp144548_c0_seq1,1533,38.3562,0.33846633,99,94,,7.00E-07,Q7PYI7,Cryptochrome-1 (agCRY1),Cryptochrome-1 (agCRY1),GO:0003913; GO:0006281; GO:0009882; GO:0005737; GO:0050660; GO:0045892; GO:0005641; GO:0048471; GO:0000060; GO:0018298; GO:0042752; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; blue light photoreceptor activity; cytoplasm; flavin adenine dinucleotide binding; negative regulation of transcription, DNA-dependent; nuclear envelope lumen; perinuclear region of cytoplasm; protein import into nucleus, translocation; protein-chromophore linkage; regulation of circadian rhythm; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,,,,,,,,,CRY1_ANOGA,Anopheles gambiae (African malaria mosquito),"negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; protein import into nucleus, translocation [GO:0000060]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144548_c0_seq2,1545,38.1877,0.33894134,178,161,,4.00E-20,Q5IZC5,Cryptochrome-1,Cryptochrome-1,GO:0003677; GO:0003913; GO:0006281; GO:0000166; GO:0005634; GO:0009881; GO:0018298; GO:0006355; GO:0048511; GO:0006351,"DNA binding; DNA photolyase activity; DNA repair; nucleotide binding; nucleus; photoreceptor activity; protein-chromophore linkage; regulation of transcription, DNA-dependent; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,3.00E-56,CHOYP_CRY1.2.2,,,,,,,CRY1_ERIRU,Erithacus rubecula (European robin),"protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp144550_c0_seq1,3125,39.84,0.4873537,8,12,,8.00E-123,F4I0P8,Vacuolar protein sorting-associated protein 35B (Vesicle protein sorting 35B),Vacuolar protein sorting-associated protein 35B (Vesicle protein sorting 35B),GO:0005794; GO:0031902; GO:0015031,Golgi apparatus; late endosome membrane; protein transport,PF03635;,,,,,,,,,VP35B_ARATH,Arabidopsis thaliana (Mouse-ear cress),"intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]" comp144550_c0_seq2,3440,39.9419,0.4481531,105,634,,0,Q96QK1,Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35),Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35),GO:0008219; GO:0005829; GO:0005768; GO:0005765; GO:0015031; GO:0042147,"cell death; cytosol; endosome; lysosomal membrane; protein transport; retrograde transport, endosome to Golgi",PF03635;,0,CHOYP_VPS35.1.1,,,,,,,VPS35_HUMAN,Homo sapiens (Human),"intracellular protein transport [GO:0006886]; negative regulation of late endosome to lysosome transport [GO:1902823]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt protein secretion [GO:0061357]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; transcytosis [GO:0045056]; Wnt signaling pathway [GO:0016055]" comp144551_c0_seq1,3074,46.9096,0.46301462,313,1124,,0,P41252,"Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)","Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)",GO:0005524; GO:0002161; GO:0005829; GO:0004822; GO:0006428; GO:0005634; GO:0006450; GO:0006418,ATP binding; aminoacyl-tRNA editing activity; cytosol; isoleucine-tRNA ligase activity; isoleucyl-tRNA aminoacylation; nucleus; regulation of translational fidelity; tRNA aminoacylation for protein translation,PF08264;PF00133;,0,CHOYP_IARS.1.1,,,,,,,SYIC_HUMAN,Homo sapiens (Human),isoleucyl-tRNA aminoacylation [GO:0006428]; osteoblast differentiation [GO:0001649]; tRNA aminoacylation for protein translation [GO:0006418] comp144551_c0_seq2,1871,47.3544,0.42604224,0,61,,0,P41252,"Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)","Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)",GO:0005524; GO:0002161; GO:0005829; GO:0004822; GO:0006428; GO:0005634; GO:0006450; GO:0006418,ATP binding; aminoacyl-tRNA editing activity; cytosol; isoleucine-tRNA ligase activity; isoleucyl-tRNA aminoacylation; nucleus; regulation of translational fidelity; tRNA aminoacylation for protein translation,PF08264;PF00133;,,,,,,,,,SYIC_HUMAN,Homo sapiens (Human),isoleucyl-tRNA aminoacylation [GO:0006428]; osteoblast differentiation [GO:0001649]; tRNA aminoacylation for protein translation [GO:0006418] comp144553_c0_seq1,11361,44.2391,0.45310662,752,179,,0,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYH2.1.1,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp144553_c0_seq2,1229,47.8438,0.43910305,3,0,,,,,,,,,2.00E-19,CHOYP_LOC101242248.2.2,,,,,,,,, comp144553_c0_seq3,10153,46.5183,0.43832998,96,0,,0,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYH2.1.1,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp144556_c0_seq3,999,47.6476,1.11228925,143,412,,4.00E-39,Q04202,Transposable element Tcb2 transposase,Transposable element Tcb2 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,5.00E-71,CHOYP_PMAR_PMAR021704.1.1,,,,,,,TCB2_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp144556_c0_seq4,685,51.8248,1.13230307,11,42,,4.00E-28,Q04202,Transposable element Tcb2 transposase,Transposable element Tcb2 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,3.00E-40,CHOYP_LOC100373346.1.2,,,,,,,TCB2_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp144557_c0_seq1,4722,43.6891,0.56414665,138,262,,0,Q96C45,Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4),Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4),GO:0005524; GO:0060271; GO:0003351; GO:0004674; GO:0021591,ATP binding; cilium morphogenesis; epithelial cilium movement; protein serine/threonine kinase activity; ventricular system development,PF00069;,0,CHOYP_ULK4.2.3,,,,,,,ULK4_HUMAN,Homo sapiens (Human),microtubule cytoskeleton organization [GO:0000226]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036] comp144557_c0_seq2,3671,42.9038,0.55699753,21,85,,,,,,,,,0,CHOYP_ULK4.2.3,,,,,,,,, comp144560_c0_seq2,2834,43.825,0.43321562,59,0,,,,,,,,,5.00E-44,CHOYP_MUD.2.3,,,,,,,,, comp144561_c0_seq1,7191,45.2093,0.41397413,1174,11392,,0,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,0,CHOYP_FASN.3.4,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp144563_c0_seq1,4928,44.1356,0.61184213,29,6,,3.00E-22,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp144563_c0_seq3,1670,45.8084,0.61521758,17,9,,3.00E-23,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp144564_c0_seq1,6356,38.2788,0.37139073,555,80,,2.00E-35,Q9D4I2,Meiosis inhibitor protein 1 (Meiosis defective protein 1),Meiosis inhibitor protein 1 (Meiosis defective protein 1),GO:0007141; GO:0007286,male meiosis I; spermatid development,,,,,,,,,,MEII1_MOUSE,Mus musculus (Mouse),gamete generation [GO:0007276]; male meiosis I [GO:0007141]; meiotic nuclear division [GO:0007126]; meiotic telomere clustering [GO:0045141]; spermatid development [GO:0007286] comp144564_c0_seq2,2515,33.5586,0.36800186,39,71,,,,,,,,,,,8.00E-14,ruditapes_c9566,,,,,,, comp144566_c2_seq1,2066,42.8848,0.54073046,457,838,,0,Q9CQN1,"Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)","Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)",GO:0005524; GO:0005743; GO:0005759; GO:1901856; GO:0006457; GO:0006950,ATP binding; mitochondrial inner membrane; mitochondrial matrix; negative regulation of cellular respiration; protein folding; response to stress,PF00183;,0,CHOYP_TRAP1.1.1,,,,,,,TRAP1_MOUSE,Mus musculus (Mouse),negative regulation of cellular respiration [GO:1901856]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; protein folding [GO:0006457]; response to stress [GO:0006950]; translational attenuation [GO:0009386] comp144567_c0_seq1,1384,39.4509,0.78155061,11,6,,2.00E-10,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp144567_c0_seq4,1041,37.2719,0.63923029,0,0,,2.00E-11,Q7JQ07,Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),GO:0003677; GO:0015074; GO:0006310; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA integration; DNA recombination; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF01359;,,,,,,,,,MOS1T_DROMA,Drosophila mauritiana (Fruit fly),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp144567_c0_seq5,1052,37.2624,0.63281307,50,137,,1.00E-13,Q7JQ07,Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase),GO:0003677; GO:0015074; GO:0006310; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA integration; DNA recombination; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF01359;,,,,,,,,,MOS1T_DROMA,Drosophila mauritiana (Fruit fly),DNA integration [GO:0015074]; DNA recombination [GO:0006310] comp144567_c0_seq7,1023,37.8299,0.91379211,5,23,,2.00E-12,Q3ZCU0,Putative uncharacterized protein FLJ37770,Putative uncharacterized protein FLJ37770,,,,,,,,,,,,YK006_HUMAN,Homo sapiens (Human), comp144568_c0_seq1,1748,34.5538,0.42339362,198,1226,,3.00E-30,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,3.00E-20,CHOYP_LOC101240925.1.1,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144569_c0_seq5,608,46.0526,0.31085787,51,704,,7.00E-16,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp144569_c0_seq9,694,45.6772,0.33373419,69,480,,3.00E-16,Q8YV57,Uncharacterized WD repeat-containing protein all2124,Uncharacterized WD repeat-containing protein all2124,GO:0004197; GO:0006508,cysteine-type endopeptidase activity; proteolysis,PF12894;PF00400;,6.00E-43,CHOYP_BRAFLDRAFT_128562.3.4,,,,,,,Y2124_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp144570_c0_seq1,5773,45.3317,0.46787299,7,0,,0,Q63164,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DYH1.1.1,,,,,,,DYH1_RAT,Rattus norvegicus (Rat),cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp144570_c0_seq10,407,45.9459,0.24182223,0,0,,6.00E-23,Q19542,Cytoplasmic dynein 2 heavy chain 1 (Abnormal chemotaxis protein 3),Cytoplasmic dynein 2 heavy chain 1 (Abnormal chemotaxis protein 3),GO:0005524; GO:0006200; GO:0016887; GO:0007635; GO:0001539; GO:0005929; GO:0042384; GO:0060170; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0007275; GO:0030512; GO:0008104,ATP binding; ATP catabolic process; ATPase activity; chemosensory behavior; ciliary or bacterial-type flagellar motility; cilium; cilium assembly; cilium membrane; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; multicellular organismal development; negative regulation of transforming growth factor beta receptor signaling pathway; protein localization,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,1.00E-42,CHOYP_LOC100378331.1.1,,,,,,,DYHC2_CAEEL,Caenorhabditis elegans,chemosensory behavior [GO:0007635]; cilium assembly [GO:0042384]; dauer entry [GO:0043053]; microtubule-based movement [GO:0007018]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of dauer larval development [GO:0061066]; protein localization [GO:0008104] comp144570_c0_seq2,7605,43.1032,0.45265676,41,5,,0,Q63164,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,,,2.00E-20,ruditapes_c237,,,,,DYH1_RAT,Rattus norvegicus (Rat),cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp144570_c0_seq3,9878,44.0777,0.47398104,3,0,,0,Q63170,"Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)","Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0005509; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; calcium ion binding; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DYH1.1.1,1.00E-17,ruditapes_c22262,,,,,DYH7_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341] comp144570_c0_seq6,10063,43.9432,0.47003877,117,0,,0,Q63164,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DYH1.1.1,,,,,,,DYH1_RAT,Rattus norvegicus (Rat),cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp144570_c0_seq7,3740,45.5615,0.3785519,390,0,male,0,Q9P2D7,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018; GO:0009612,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement; response to mechanical stimulus,PF07728;PF12780;PF08393;PF03028;PF12777;,,,5.00E-31,ruditapes_c19283,,,,,DYH1_HUMAN,Homo sapiens (Human),cilium movement involved in cell motility [GO:0060294]; cilium or flagellum-dependent cell motility [GO:0001539]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; response to mechanical stimulus [GO:0009612]; sperm motility [GO:0030317] comp144570_c0_seq8,1592,43.9698,0.57369719,3,0,,4.00E-118,Q3V0Q1,"Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)","Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0016567,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; protein ubiquitination,PF07728;PF12780;PF08393;PF03028;,1.00E-55,CHOYP_DNAH12.1.3,,,,,,,DYH12_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018]; protein ubiquitination [GO:0016567] comp144570_c0_seq9,1282,43.9938,0.56752727,0,0,,,,,,,,,8.00E-114,CHOYP_DYH1.1.1,,,,,,,,, comp144571_c0_seq1,5062,42.4141,0.43022541,1103,341,,8.00E-99,A9JR78,Tonsoku-like protein (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2),Tonsoku-like protein (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2),GO:0005737; GO:0000724; GO:0042393; GO:0043596; GO:0031297,cytoplasm; double-strand break repair via homologous recombination; histone binding; nuclear replication fork; replication fork processing,PF12796;PF13516;PF13176;PF13181;,,,,,,,,,TONSL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] comp144571_c0_seq2,1998,44.044,0.41752055,35,0,,8.00E-103,A9JR78,Tonsoku-like protein (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2),Tonsoku-like protein (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2),GO:0005737; GO:0000724; GO:0042393; GO:0043596; GO:0031297,cytoplasm; double-strand break repair via homologous recombination; histone binding; nuclear replication fork; replication fork processing,PF12796;PF13516;PF13176;PF13181;,1.00E-18,CHOYP_TONSL.1.1,,,,,,,TONSL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] comp144573_c1_seq2,3653,40.2956,0.28896963,250,36,,5.00E-48,Q5VXU9,Uncharacterized protein C9orf84,Uncharacterized protein C9orf84,,,,,,,,,,,,CI084_HUMAN,Homo sapiens (Human), comp144573_c1_seq5,1408,41.1222,0.2600912,0,0,,2.00E-44,Q5VXU9,Uncharacterized protein C9orf84,Uncharacterized protein C9orf84,,,,,,,,,,,,CI084_HUMAN,Homo sapiens (Human), comp144574_c0_seq1,7238,43.0229,0.60435047,906,508,,0,P62296,Abnormal spindle-like microcephaly-associated protein homolog,Abnormal spindle-like microcephaly-associated protein homolog,GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,7.00E-54,CHOYP_LOC101174988.1.1,,,,,,,ASPM_SAIBB,Saimiri boliviensis boliviensis (Bolivian squirrel monkey),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp144574_c0_seq4,4111,41.7903,0.56018978,0,0,,1.00E-33,P62290,Abnormal spindle-like microcephaly-associated protein homolog,Abnormal spindle-like microcephaly-associated protein homolog,GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0005819,cell division; cytoplasm; mitosis; nucleus; spindle,PF15780;PF00307;PF00612;,,,,,,,,,ASPM_HYLLA,Hylobates lar (Common gibbon) (White-handed gibbon),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051] comp144575_c0_seq2,5586,42.9108,0.59507391,3314,4530,,2.00E-13,Q8QFX1,RIMS-binding protein 2 (RIM-BP2),RIMS-binding protein 2 (RIM-BP2),GO:0030054; GO:0010923; GO:0005886; GO:0045202,cell junction; negative regulation of phosphatase activity; plasma membrane; synapse,PF07653;PF14604;,9.00E-26,CHOYP_TVAG_087170.4.8,1.00E-59,ruditapes2_c440,,,,,RIMB2_CHICK,Gallus gallus (Chicken),negative regulation of phosphatase activity [GO:0010923] comp144576_c0_seq1,4949,42.453,0.44129689,10,11,,0,A8WGF4,Intraflagellar transport protein 122 homolog,Intraflagellar transport protein 122 homolog,GO:0005737; GO:0035721; GO:0030991; GO:0005932; GO:0007275; GO:0045879; GO:0072372,cytoplasm; intraflagellar retrograde transport; intraflagellar transport particle A; microtubule basal body; multicellular organismal development; negative regulation of smoothened signaling pathway; primary cilium,PF00400;,,,,,,,,,IF122_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium assembly [GO:0042384]; intraciliary retrograde transport [GO:0035721]; multicellular organism development [GO:0007275]; negative regulation of smoothened signaling pathway [GO:0045879]; protein localization to cilium [GO:0061512] comp144576_c0_seq2,4854,42.5422,0.4390768,0,0,,0,Q9HBG6,Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140),Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140),GO:0048593; GO:0060830; GO:0060271; GO:0005737; GO:0010172; GO:0042733; GO:0035050; GO:0035721; GO:0030991; GO:0060173; GO:0005932; GO:0045879; GO:0001843; GO:0032391; GO:0060831,camera-type eye morphogenesis; ciliary receptor clustering involved in smoothened signaling pathway; cilium morphogenesis; cytoplasm; embryonic body morphogenesis; embryonic digit morphogenesis; embryonic heart tube development; intraflagellar retrograde transport; intraflagellar transport particle A; limb development; microtubule basal body; negative regulation of smoothened signaling pathway; neural tube closure; photoreceptor connecting cilium; smoothened signaling pathway involved in dorsal/ventral neural tube patterning,PF00400;,0,CHOYP_IF122.2.2,,,,,,,IF122_HUMAN,Homo sapiens (Human),camera-type eye morphogenesis [GO:0048593]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; embryonic body morphogenesis [GO:0010172]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic heart tube development [GO:0035050]; embryonic heart tube left/right pattern formation [GO:0060971]; establishment of protein localization to organelle [GO:0072594]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; neural tube closure [GO:0001843]; protein localization to cilium [GO:0061512]; signal transduction downstream of smoothened [GO:0007227]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] comp144576_c0_seq3,5116,42.9242,0.44785881,11,20,,3.00E-08,Q00808,Vegetative incompatibility protein HET-E-1,Vegetative incompatibility protein HET-E-1,GO:0005525,GTP binding,PF06985;PF00400;,1.00E-136,CHOYP_IF122.1.2,,,,,,,HETE1_PODAS,Podospora anserina (Pleurage anserina), comp144576_c0_seq4,5215,42.8188,0.44557055,5,31,,0,A8WGF4,Intraflagellar transport protein 122 homolog,Intraflagellar transport protein 122 homolog,GO:0005737; GO:0035721; GO:0030991; GO:0005932; GO:0007275; GO:0045879; GO:0072372,cytoplasm; intraflagellar retrograde transport; intraflagellar transport particle A; microtubule basal body; multicellular organismal development; negative regulation of smoothened signaling pathway; primary cilium,PF00400;,0,CHOYP_IF122.2.2,,,,,,,IF122_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium assembly [GO:0042384]; intraciliary retrograde transport [GO:0035721]; multicellular organism development [GO:0007275]; negative regulation of smoothened signaling pathway [GO:0045879]; protein localization to cilium [GO:0061512] comp144577_c0_seq1,1261,48.1364,0.53874985,300,47,,,,,,,,,2.00E-160,CHOYP_LOC100374785.1.3,,,,,,,,, comp144577_c0_seq2,6874,46.7704,0.39110009,2429,326,,3.00E-119,Q8IYW2,Tetratricopeptide repeat protein 40,Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40),,,,,,,,,,,,TTC40_HUMAN,Homo sapiens (Human),axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294] comp144578_c0_seq1,4349,38.8825,0.47049785,1585,5218,,6.00E-36,Q68CJ6,Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),GO:0005525; GO:0006184; GO:0003924; GO:0005634,GTP binding; GTP catabolic process; GTPase activity; nucleus,PF00350;,3.00E-12,CHOYP_SLIP.1.1,,,,,,,SLIP_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp144579_c0_seq1,6389,38.9263,0.52646774,1180,3179,,0,Q6ZQ38,Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1),Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1),GO:0010265; GO:0030154; GO:0031461; GO:0005737; GO:0043086; GO:0005634; GO:0045893; GO:0016567,"SCF complex assembly; cell differentiation; cullin-RING ubiquitin ligase complex; cytoplasm; negative regulation of catalytic activity; nucleus; positive regulation of transcription, DNA-dependent; protein ubiquitination",PF08623;,0,CHOYP_BRAFLDRAFT_118260.1.1,,,,,,,CAND1_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; negative regulation of catalytic activity [GO:0043086]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265]" comp14457_c0_seq1,405,40.4938,0.33565019,10,7,,2.00E-28,Q6DFJ6,Serine/threonine-protein kinase TBK1 (EC 2.7.11.1),Serine/threonine-protein kinase TBK1 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0045087; GO:0004674,ATP binding; cytoplasm; innate immune response; protein serine/threonine kinase activity,PF00069;,,,,,,,,,TBK1_XENLA,Xenopus laevis (African clawed frog),innate immune response [GO:0045087] comp144581_c0_seq1,6869,47.8236,0.37164488,506,42,,0,Q27802,Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),GO:0005524; GO:0006200; GO:0016887; GO:0030031; GO:0001539; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0007275; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; cell projection assembly; ciliary or bacterial-type flagellar motility; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; multicellular organismal development; plasma membrane,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC2.2.2,,,,,,,DYHC2_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275] comp144581_c0_seq10,2921,49.0585,0.45554443,0,0,,0,Q9SMH5,Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein heavy chain 1b) (cDHC1b),Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein heavy chain 1b) (cDHC1b),GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0072594; GO:0005874; GO:0005932; GO:0003777; GO:0007018; GO:0044458; GO:0003774; GO:0007275; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; establishment of protein localization to organelle; microtubule; microtubule basal body; microtubule motor activity; microtubule-based movement; motile cilium assembly; motor activity; multicellular organismal development; plasma membrane,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHC2_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),establishment of protein localization to organelle [GO:0072594]; microtubule-based movement [GO:0007018]; motile cilium assembly [GO:0044458]; multicellular organism development [GO:0007275] comp144581_c0_seq11,1803,49.0849,0.4446287,0,0,,2.00E-06,Q96M86,Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35),Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35),GO:0030031; GO:0001539; GO:0030286; GO:0003777; GO:0007018,cell projection assembly; ciliary or bacterial-type flagellar motility; dynein complex; microtubule motor activity; microtubule-based movement,PF08393;PF03028;PF12777;,,,,,,,,,DNHD1_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144581_c0_seq12,1770,49.435,0.44680466,0,0,,6.00E-84,P38650,"Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) (MAP 1C)","Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) (MAP 1C)",GO:0005524; GO:0006200; GO:0016887; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; transport,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHC1_RAT,Rattus norvegicus (Rat),microtubule-based movement [GO:0007018]; transport [GO:0006810] comp144581_c0_seq13,3513,49.8719,0.44782861,0,0,,0,Q27802,Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),GO:0005524; GO:0006200; GO:0016887; GO:0030031; GO:0001539; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0007275; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; cell projection assembly; ciliary or bacterial-type flagellar motility; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; multicellular organismal development; plasma membrane,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHC2_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275] comp144581_c0_seq14,3480,50.0575,0.4487733,0,0,,0,Q27802,Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),GO:0005524; GO:0006200; GO:0016887; GO:0030031; GO:0001539; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0007275; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; cell projection assembly; ciliary or bacterial-type flagellar motility; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; multicellular organismal development; plasma membrane,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC2.2.2,,,,,,,DYHC2_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275] comp144581_c0_seq5,3415,49.0483,0.39411826,4,0,,0,Q27802,Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),GO:0005524; GO:0006200; GO:0016887; GO:0030031; GO:0001539; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0007275; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; cell projection assembly; ciliary or bacterial-type flagellar motility; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; multicellular organismal development; plasma membrane,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-32,CHOYP_DYHC1.1.1,,,,,,,DYHC2_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275] comp144581_c0_seq7,4056,49.2357,0.3677851,13,0,,0,Q27802,Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B),GO:0005524; GO:0006200; GO:0016887; GO:0030031; GO:0001539; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0007275; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; cell projection assembly; ciliary or bacterial-type flagellar motility; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; multicellular organismal development; plasma membrane,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC2.2.2,,,,,,,DYHC2_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275] comp144581_c0_seq8,2888,49.2729,0.45683666,0,0,,2.00E-89,Q63164,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DYHC2.2.2,,,,,,,DYH1_RAT,Rattus norvegicus (Rat),cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp144582_c0_seq1,3425,38.5401,0.51638984,3,0,,6.00E-57,Q94F88,DNA (cytosine-5)-methyltransferase CMT3 (EC 2.1.1.37) (Chromomethylase 3) (Protein CHROMOMETHYLASE 3),DNA (cytosine-5)-methyltransferase CMT3 (EC 2.1.1.37) (Chromomethylase 3) (Protein CHROMOMETHYLASE 3),GO:0003886; GO:0003677; GO:0010425; GO:0006342; GO:0051567; GO:0005634; GO:0006351; GO:0010069,"DNA (cytosine-5-)-methyltransferase activity; DNA binding; DNA methylation on cytosine within a CNG sequence; chromatin silencing; histone H3-K9 methylation; nucleus; transcription, DNA-dependent; zygote asymmetric cytokinesis in embryo sac",PF01426;PF00385;PF00145;,,,,,,,,,CMT3_ARATH,Arabidopsis thaliana (Mouse-ear cress),"chromatin silencing [GO:0006342]; DNA methylation [GO:0006306]; DNA methylation on cytosine within a CNG sequence [GO:0010425]; histone H3-K9 methylation [GO:0051567]; negative regulation of gene expression, epigenetic [GO:0045814]; transcription, DNA-templated [GO:0006351]; zygote asymmetric cytokinesis in embryo sac [GO:0010069]" comp144582_c0_seq2,6547,41.6068,0.51972838,86,97,,0,Q92072,DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT),DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT),GO:0003886; GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA (cytosine-5-)-methyltransferase activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01426;PF06464;PF00145;PF12047;PF02008;,0,CHOYP_DNMT1.1.1,,,,,,,DNMT1_CHICK,Gallus gallus (Chicken),"positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]" comp144582_c0_seq3,6234,41.5784,0.50364959,10,13,,0,Q92072,DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT),DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT),GO:0003886; GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA (cytosine-5-)-methyltransferase activity; DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01426;PF06464;PF00145;PF12047;PF02008;,0,CHOYP_DNMT1.1.1,,,,,,,DNMT1_CHICK,Gallus gallus (Chicken),"positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]" comp144582_c0_seq4,3101,37.7298,0.54818412,0,10,,9.00E-10,P25265,Modification methylase HgiDII (M.HgiDII) (EC 2.1.1.37) (Cytosine-specific methyltransferase HgiDII),Modification methylase HgiDII (M.HgiDII) (EC 2.1.1.37) (Cytosine-specific methyltransferase HgiDII),GO:0090116; GO:0003886; GO:0003677; GO:0009307,C-5 methylation of cytosine; DNA (cytosine-5-)-methyltransferase activity; DNA binding; DNA restriction-modification system,PF00145;,,,,,,,,,MTD2_HERAU,Herpetosiphon aurantiacus (Herpetosiphon giganteus),DNA restriction-modification system [GO:0009307] comp144584_c0_seq1,3173,50.1733,0.51098209,21,0,,,,,,,,,5.00E-13,CHOYP_TRIADDRAFT_51343.1.2,,,,,,,,, comp144584_c0_seq15,1316,46.8845,0.51211775,0,0,,,,,,,,,4.00E-61,CHOYP_LOC585963.2.2,6.00E-18,ruditapes_c20435,,,,,,, comp144584_c0_seq2,3248,50.3695,0.50983828,19,0,,,,,,,,,6.00E-13,CHOYP_TRIADDRAFT_51343.1.2,,,,,,,,, comp144584_c0_seq4,4749,50.4527,0.56317501,282,13,,,,,,,,,2.00E-91,CHOYP_LOC585963.2.2,,,,,,,,, comp144584_c0_seq9,2209,51.5165,0.60176072,6,0,,,,,,,,,3.00E-26,CHOYP_LOC585963.2.2,,,,,,,,, comp144586_c0_seq11,395,46.8354,0.7431434,0,0,,8.00E-16,Q8K4L3,Supervillin (Archvillin) (p205/p250),Supervillin (Archvillin) (p205/p250),GO:0030054; GO:0043034; GO:0007010; GO:0071437; GO:0005634; GO:0005886; GO:0002102; GO:0007519,cell junction; costamere; cytoskeleton organization; invadopodium; nucleus; plasma membrane; podosome; skeletal muscle tissue development,PF00626;PF02209;,5.00E-28,CHOYP_LOC578781.5.5,,,,,,,SVIL_MOUSE,Mus musculus (Mouse),cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519] comp144586_c0_seq2,6379,45.7282,0.68821235,4,0,,0,O46385,Supervillin (Archvillin) (p205/p250),Supervillin (Archvillin) (p205/p250),GO:0030054; GO:0005737; GO:0007010; GO:0071437; GO:0005886; GO:0002102,cell junction; cytoplasm; cytoskeleton organization; invadopodium; plasma membrane; podosome,PF00626;PF02209;,4.00E-170,CHOYP_LOC578781.3.5,,,,,,,SVIL_BOVIN,Bos taurus (Bovine),cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467] comp144586_c0_seq3,2120,45.2358,0.70691334,12,11,,9.00E-157,O46385,Supervillin (Archvillin) (p205/p250),Supervillin (Archvillin) (p205/p250),GO:0030054; GO:0005737; GO:0007010; GO:0071437; GO:0005886; GO:0002102,cell junction; cytoplasm; cytoskeleton organization; invadopodium; plasma membrane; podosome,PF00626;PF02209;,,,,,,,,,SVIL_BOVIN,Bos taurus (Bovine),cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467] comp144586_c0_seq5,2109,45.2347,0.71083782,0,0,,7.00E-40,Q8WQ85,Villidin,Villidin,GO:0051015; GO:0030864; GO:0007010; GO:0030835; GO:0001891; GO:0045335; GO:0005543; GO:0051707,actin filament binding; cortical actin cytoskeleton; cytoskeleton organization; negative regulation of actin filament depolymerization; phagocytic cup; phagocytic vesicle; phospholipid binding; response to other organism,PF08953;PF00626;PF00169;PF02209;PF00400;,,,,,,,,,VILD_DICDI,Dictyostelium discoideum (Slime mold),cytoskeleton organization [GO:0007010]; positive phototaxis [GO:0046956]; response to other organism [GO:0051707] comp144586_c0_seq7,4665,46.0665,0.68250588,0,0,,6.00E-13,O81644,Villin-2,Villin-2,GO:0051017; GO:0051693; GO:0005737; GO:0005856,actin filament bundle assembly; actin filament capping; cytoplasm; cytoskeleton,PF00626;PF02209;,,,,,,,,,VILI2_ARATH,Arabidopsis thaliana (Mouse-ear cress),actin filament bundle assembly [GO:0051017]; actin filament capping [GO:0051693] comp144586_c0_seq9,6390,45.7121,0.68440975,0,30,,0,O46385,Supervillin (Archvillin) (p205/p250),Supervillin (Archvillin) (p205/p250),GO:0030054; GO:0005737; GO:0007010; GO:0071437; GO:0005886; GO:0002102,cell junction; cytoplasm; cytoskeleton organization; invadopodium; plasma membrane; podosome,PF00626;PF02209;,2.00E-167,CHOYP_LOC578781.3.5,,,,,,,SVIL_BOVIN,Bos taurus (Bovine),cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467] comp144587_c0_seq10,2479,39.6934,0.54106905,24,157,,2.00E-149,Q9BWD1,"Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)","Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)",GO:0003985; GO:0006629; GO:0005739; GO:0005730,acetyl-CoA C-acetyltransferase activity; lipid metabolic process; mitochondrion; nucleolus,PF02803;PF00108;,2.00E-99,CHOYP_BRAFLDRAFT_109688.1.1,,,,,,,THIC_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629] comp144587_c0_seq12,1923,35.8294,0.68285776,27,413,,2.00E-58,Q7SZC2,Exportin-2 (Exp2) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter),Exportin-2 (Exp2) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter),GO:0007589; GO:0005737; GO:0006886; GO:0005634,body fluid secretion; cytoplasm; intracellular protein transport; nucleus,PF03378;PF08506;PF03810;,,,,,,,,,XPO2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),body fluid secretion [GO:0007589]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606] comp144587_c0_seq5,2418,40.4467,0.55380046,31,244,,1.00E-150,Q9BWD1,"Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)","Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)",GO:0003985; GO:0006629; GO:0005739; GO:0005730,acetyl-CoA C-acetyltransferase activity; lipid metabolic process; mitochondrion; nucleolus,PF02803;PF00108;,,,,,,,,,THIC_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629] comp144587_c0_seq7,4468,38.8093,0.58294747,504,3054,,0,Q8AY73,Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter),Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter),GO:0005737; GO:0006886; GO:0005634,cytoplasm; intracellular protein transport; nucleus,PF03378;PF08506;PF03810;,0,CHOYP_XPO2.1.1,,,,,,,XPO2_ORENI,Oreochromis niloticus (Nile tilapia) (Tilapia nilotica),body fluid secretion [GO:0007589]; intracellular protein transport [GO:0006886] comp144588_c0_seq1,877,47.3204,0.53541678,143497,369587,,8.00E-150,P15880,40S ribosomal protein S2 (40S ribosomal protein S4) (Protein LLRep3),40S ribosomal protein S2 (40S ribosomal protein S4) (Protein LLRep3),GO:0006614; GO:0022627; GO:0003729; GO:0000184; GO:0005654; GO:0051347; GO:0003735; GO:0006414; GO:0006413; GO:0006415; GO:0019083,"SRP-dependent cotranslational protein targeting to membrane; cytosolic small ribosomal subunit; mRNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleoplasm; positive regulation of transferase activity; structural constituent of ribosome; translational elongation; translational initiation; translational termination; viral transcription",PF00333;PF03719;,1.00E-178,CHOYP_RS2.2.10,0,ruditapes_c226,,,,,RS2_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transferase activity [GO:0051347]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]" comp144588_c2_seq1,1929,53.2919,1.08710905,28957409,8450932,,1.00E-17,Q8TGM7,Putative uncharacterized protein ART2 (Antisense to ribosomal RNA transcript protein 2),Putative uncharacterized protein ART2 (Antisense to ribosomal RNA transcript protein 2),,,,0,CHOYP_RN45S.3.5,,,,,,,ART2_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp144588_c3_seq1,2362,54.2337,1.09181538,27102977,7139078,,,,,,,,,0,CHOYP_LOC101165464.1.1,,,,,,,,, comp144588_c4_seq1,1889,57.7025,1.07439031,22927597,7434931,,1.00E-06,Q8TGM6,Protein TAR1 (Transcript antisense to ribosomal RNA protein 1),Protein TAR1 (Transcript antisense to ribosomal RNA protein 1),GO:0005739; GO:0043457,mitochondrion; regulation of cellular respiration,,0,CHOYP_RN28S1.1.1,,,,,,,TAR1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),regulation of cellular respiration [GO:0043457] comp144589_c0_seq1,3395,46.8041,0.71887545,2,0,,4.00E-34,Q99996,A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),GO:0000086; GO:0005794; GO:0005813; GO:0005829; GO:0000242; GO:0032947; GO:0005102; GO:0007165; GO:0007268; GO:0006810; GO:0008076,G2/M transition of mitotic cell cycle; Golgi apparatus; centrosome; cytosol; pericentriolar material; protein complex scaffold; receptor binding; signal transduction; synaptic transmission; transport; voltage-gated potassium channel complex,PF10495;,3.00E-16,CHOYP_LOC582174.16.16,,,,,,,AKAP9_HUMAN,Homo sapiens (Human),cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810] comp144589_c0_seq2,4851,47.1655,0.62298473,316,80,,2.00E-28,O95613,Pericentrin (Kendrin) (Pericentrin-B),Pericentrin (Kendrin) (Pericentrin-B),GO:0000086; GO:0006915; GO:0048854; GO:0005814; GO:0005813; GO:0021696; GO:0042384; GO:0005829; GO:0001701; GO:0045171; GO:0035108; GO:0005874; GO:0000226; GO:0035264; GO:0061351; GO:0001764; GO:0021772; GO:0007051,G2/M transition of mitotic cell cycle; apoptotic process; brain morphogenesis; centriole; centrosome; cerebellar cortex morphogenesis; cilium assembly; cytosol; in utero embryonic development; intercellular bridge; limb morphogenesis; microtubule; microtubule cytoskeleton organization; multicellular organism growth; neural precursor cell proliferation; neuron migration; olfactory bulb development; spindle organization,PF10495;,6.00E-34,CHOYP_LOC582174.2.16,,,,,,,PCNT_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; positive regulation of intracellular protein transport [GO:0090316] comp144589_c0_seq5,3009,46.9259,0.71744493,0,0,,5.00E-34,Q99996,A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao),GO:0000086; GO:0005794; GO:0005813; GO:0005829; GO:0000242; GO:0032947; GO:0005102; GO:0007165; GO:0007268; GO:0006810; GO:0008076,G2/M transition of mitotic cell cycle; Golgi apparatus; centrosome; cytosol; pericentriolar material; protein complex scaffold; receptor binding; signal transduction; synaptic transmission; transport; voltage-gated potassium channel complex,PF10495;,,,,,,,,,AKAP9_HUMAN,Homo sapiens (Human),cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810] comp144589_c0_seq6,2954,46.5132,0.71849241,2,0,,2.00E-24,P48725,Pericentrin,Pericentrin,GO:0048854; GO:0005814; GO:0021696; GO:0001701; GO:0045171; GO:0035108; GO:0005874; GO:0035264; GO:0043066; GO:0061351; GO:0001764; GO:0021772; GO:0007051,brain morphogenesis; centriole; cerebellar cortex morphogenesis; in utero embryonic development; intercellular bridge; limb morphogenesis; microtubule; multicellular organism growth; negative regulation of apoptotic process; neural precursor cell proliferation; neuron migration; olfactory bulb development; spindle organization,PF10495;,3.00E-16,CHOYP_LOC582174.16.16,,,,,,,PCNT_MOUSE,Mus musculus (Mouse),brain morphogenesis [GO:0048854]; camera-type eye development [GO:0043010]; cerebellar cortex morphogenesis [GO:0021696]; cilium assembly [GO:0042384]; embryonic brain development [GO:1990403]; embryonic heart tube development [GO:0035050]; head development [GO:0060322]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural precursor cell proliferation [GO:0061351]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; positive regulation of intracellular protein transport [GO:0090316]; spindle organization [GO:0007051]; vasculature development [GO:0001944] comp144589_c1_seq2,2120,46.4151,0.61118752,0,0,,2.00E-06,Q70FJ1,A-kinase anchor protein 9 (AKAP-9) (Protein kinase A-anchoring protein 9) (PRKA9),A-kinase anchor protein 9 (AKAP-9) (Protein kinase A-anchoring protein 9) (PRKA9),GO:0005794; GO:0000242,Golgi apparatus; pericentriolar material,PF10495;,4.00E-25,CHOYP_LOC100368547.20.40,,,,,,,AKAP9_MOUSE,Mus musculus (Mouse),microtubule nucleation [GO:0007020]; Sertoli cell development [GO:0060009]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] comp144590_c0_seq1,2041,38.4615,0.43708372,311,1112,,6.00E-64,O43290,U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1),U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1),GO:0015030; GO:0005794; GO:0071013; GO:0007050; GO:0005829; GO:0097193; GO:0045585; GO:0000387,Cajal body; Golgi apparatus; catalytic step 2 spliceosome; cell cycle arrest; cytosol; intrinsic apoptotic signaling pathway; positive regulation of cytotoxic T cell differentiation; spliceosomal snRNP assembly,PF03343;,3.00E-51,CHOYP_SART1.1.1,,,,,,,SNUT1_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; intrinsic apoptotic signaling pathway [GO:0097193]; maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387]" comp144591_c0_seq1,1822,50,0.38699293,20,0,,,,,,,,,8.00E-40,CHOYP_LOC585963.2.2,,,,,,,,, comp144591_c0_seq4,9215,46.0662,0.63915252,790,453,,,,,,,,,3.00E-66,CHOYP_TRIADDRAFT_51343.2.2,1.00E-50,ruditapes_c25272,,,,,,, comp144591_c0_seq8,668,44.7605,0.62876081,0,0,,,,,,,,,2.00E-54,CHOYP_LOC585963.2.2,,,,,,,,, comp144592_c0_seq2,17170,39.9068,0.42626768,46,91,,2.00E-100,Q9BYW2,Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP),Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP),GO:0001525; GO:0035441; GO:0005694; GO:0060977; GO:0048701; GO:0060669; GO:0030900; GO:0097198; GO:0018024; GO:0048332; GO:0006298; GO:0001763; GO:0001843; GO:0034728; GO:0005634; GO:0060039; GO:0010793; GO:0006355; GO:0048864; GO:0006368,"angiogenesis; cell migration involved in vasculogenesis; chromosome; coronary vasculature morphogenesis; embryonic cranial skeleton morphogenesis; embryonic placenta morphogenesis; forebrain development; histone H3-K36 trimethylation; histone-lysine N-methyltransferase activity; mesoderm morphogenesis; mismatch repair; morphogenesis of a branching structure; neural tube closure; nucleosome organization; nucleus; pericardium development; regulation of mRNA export from nucleus; regulation of transcription, DNA-dependent; stem cell development; transcription elongation from RNA polymerase II promoter",PF00856;PF08236;PF00397;,2.00E-58,CHOYP_SETD2.1.1,,,,,,,SETD2_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic placenta morphogenesis [GO:0060669]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; pericardium development [GO:0060039]; regulation of mRNA export from nucleus [GO:0010793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell development [GO:0048864]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp144592_c0_seq4,18024,39.6249,0.42890394,223,382,,2.00E-100,Q9BYW2,Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP),Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP),GO:0001525; GO:0035441; GO:0005694; GO:0060977; GO:0048701; GO:0060669; GO:0030900; GO:0097198; GO:0018024; GO:0048332; GO:0006298; GO:0001763; GO:0001843; GO:0034728; GO:0005634; GO:0060039; GO:0010793; GO:0006355; GO:0048864; GO:0006368,"angiogenesis; cell migration involved in vasculogenesis; chromosome; coronary vasculature morphogenesis; embryonic cranial skeleton morphogenesis; embryonic placenta morphogenesis; forebrain development; histone H3-K36 trimethylation; histone-lysine N-methyltransferase activity; mesoderm morphogenesis; mismatch repair; morphogenesis of a branching structure; neural tube closure; nucleosome organization; nucleus; pericardium development; regulation of mRNA export from nucleus; regulation of transcription, DNA-dependent; stem cell development; transcription elongation from RNA polymerase II promoter",PF00856;PF08236;PF00397;,2.00E-58,CHOYP_SETD2.1.1,5.00E-26,ruditapes_c23278,,,,,SETD2_HUMAN,Homo sapiens (Human),"angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic placenta morphogenesis [GO:0060669]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; pericardium development [GO:0060039]; regulation of mRNA export from nucleus [GO:0010793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell development [GO:0048864]; transcription elongation from RNA polymerase II promoter [GO:0006368]" comp144593_c0_seq2,4705,43.2944,0.52749082,11,0,,1.00E-36,Q4GZT3,Polycystin-2 (Polycystic kidney disease 2 protein homolog),Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2),GO:0007259; GO:0035904; GO:0045180; GO:0009925; GO:0001658; GO:0005262; GO:0005509; GO:0048763; GO:0007050; GO:0005911; GO:0071498; GO:0071464; GO:0071470; GO:0042994; GO:0050982; GO:0003127; GO:0071910; GO:0001892; GO:0031941; GO:0001947; GO:0071458; GO:0071556; GO:0005887; GO:0030027; GO:0016020; GO:0072177; GO:0072284; GO:0072218; GO:0072214; GO:0072219; GO:0072235; GO:0072075; GO:0035502; GO:0072208; GO:0005932; GO:0072686; GO:0031512; GO:2000134; GO:0060315; GO:0021915; GO:0031513; GO:0060674; GO:0002133; GO:0071158; GO:0031659; GO:0031587; GO:0045429; GO:0045944; GO:0005267; GO:0030814; GO:0090279; GO:0042127; GO:0051209; GO:0061441; GO:0061333; GO:0021510; GO:0005245; GO:0005248,"JAK-STAT cascade; aorta development; basal cortex; basal plasma membrane; branching involved in ureteric bud morphogenesis; calcium channel activity; calcium ion binding; calcium-induced calcium release activity; cell cycle arrest; cell-cell junction; cellular response to fluid shear stress; cellular response to hydrostatic pressure; cellular response to osmotic stress; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; detection of nodal flow; determination of liver left/right asymmetry; embryonic placenta development; filamentous actin; heart looping; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; lamellipodium; membrane; mesonephric duct development; metanephric S-shaped body morphogenesis; metanephric ascending thin limb development; metanephric cortex development; metanephric cortical collecting duct development; metanephric distal tubule development; metanephric mesenchyme development; metanephric part of ureteric bud development; metanephric smooth muscle tissue development; microtubule basal body; mitotic spindle; motile primary cilium; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of ryanodine-sensitive calcium-release channel activity; neural tube development; nonmotile primary cilium; placenta blood vessel development; polycystin complex; positive regulation of cell cycle arrest; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of nitric oxide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; potassium channel activity; regulation of cAMP metabolic process; regulation of calcium ion import; regulation of cell proliferation; release of sequestered calcium ion into cytosol; renal artery morphogenesis; renal tubule morphogenesis; spinal cord development; voltage-gated calcium channel activity; voltage-gated sodium channel activity",PF08016;,3.00E-24,CHOYP_LOC100375380.1.4,,,,,,,PKD2_BOVIN,Bos taurus (Bovine),"aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]" comp144593_c0_seq3,11432,44.0955,0.50002583,11,0,,9.00E-72,Q8TDX9,Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1),Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1),GO:0005262; GO:0016337; GO:0005929; GO:0050982; GO:0003127; GO:0016021; GO:0070986; GO:0016020,calcium channel activity; cell-cell adhesion; cilium; detection of mechanical stimulus; detection of nodal flow; integral to membrane; left/right axis specification; membrane,PF00801;PF08016;PF01477;PF02010;,2.00E-69,CHOYP_LOC100375380.3.4,,,,,,,PK1L1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; left/right axis specification [GO:0070986]; single organismal cell-cell adhesion [GO:0016337] comp144593_c0_seq5,13011,43.225,0.50533519,101,14,,6.00E-72,Q8TDX9,Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1),Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1),GO:0005262; GO:0016337; GO:0005929; GO:0050982; GO:0003127; GO:0016021; GO:0070986; GO:0016020,calcium channel activity; cell-cell adhesion; cilium; detection of mechanical stimulus; detection of nodal flow; integral to membrane; left/right axis specification; membrane,PF00801;PF08016;PF01477;PF02010;,2.00E-69,CHOYP_LOC100375380.3.4,,,,,,,PK1L1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; left/right axis specification [GO:0070986]; single organismal cell-cell adhesion [GO:0016337] comp144593_c0_seq6,410,44.6341,0.59854725,4,0,,1.00E-06,Q26627,Sperm receptor for egg jelly (suREJ),Sperm receptor for egg jelly (suREJ),GO:0030246; GO:0016021; GO:0007218; GO:0005886,carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00008;PF01825;PF00059;PF02010;,,,,,,,,,SUREJ_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),detection of mechanical stimulus [GO:0050982] comp144593_c0_seq8,3748,45.2775,0.52653034,0,0,,4.00E-52,Q7Z442,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005509; GO:0030246; GO:0016021; GO:0006811; GO:0007218,calcium ion binding; carbohydrate binding; integral to membrane; ion transport; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,5.00E-33,CHOYP_LOC100375380.3.4,5.00E-12,ruditapes_c18970,,,,,PK1L2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982] comp144594_c0_seq1,5460,46.1722,0.46887523,36,0,,0,Q8IVF4,"Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)","Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_LOC100374422.2.2,,,,,,,DYH10_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144594_c0_seq4,8160,45.9804,0.4472076,785,67,,0,Q8IVF4,"Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)","Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_LOC100374422.1.2,,,,,,,DYH10_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144594_c0_seq7,2827,44.2519,0.49527152,4,0,,0,Q8IVF4,"Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)","Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_LOC100374422.2.2,,,,,,,DYH10_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144596_c0_seq1,11320,44.417,0.4406573,83,11,,3.00E-175,Q6ZTR5,Uncharacterized protein CXorf22,Cilia- and flagella-associated protein 47,,,,0,CHOYP_BRAFLDRAFT_121927.1.1,,,,,,,CX022_HUMAN,Homo sapiens (Human), comp144596_c0_seq2,11337,44.4386,0.43956874,56,0,,3.00E-175,Q6ZTR5,Uncharacterized protein CXorf22,Cilia- and flagella-associated protein 47,,,,0,CHOYP_BRAFLDRAFT_121927.1.1,,,,,,,CX022_HUMAN,Homo sapiens (Human), comp144596_c0_seq3,6195,46.8281,0.38877603,21,0,,4.00E-178,Q6ZTR5,Uncharacterized protein CXorf22,Cilia- and flagella-associated protein 47,,,,0,CHOYP_BRAFLDRAFT_121927.1.1,,,,,,,CX022_HUMAN,Homo sapiens (Human), comp144597_c0_seq1,2572,44.9067,0.63439945,0,0,,1.00E-35,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,2.00E-37,CHOYP_LOC100708199.1.6,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp144597_c0_seq2,1294,48.9181,0.63372653,0,0,,1.00E-18,Q8I7P9,Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305; GO:0005634; GO:0008233; GO:0006508; GO:0006313,"DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; peptidase activity; proteolysis; transposition, DNA-mediated",PF00665;PF00078;,5.00E-21,CHOYP_LOC100695950.6.6,,,,,,,POL5_DROME,Drosophila melanogaster (Fruit fly),"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp144597_c0_seq3,1347,45.8055,0.60905781,0,0,,,,,,,,,5.00E-15,CHOYP_LOC100891763.2.2,,,,,,,,, comp144597_c0_seq4,7204,42.2682,0.51649773,12,22,,2.00E-78,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,5.00E-37,CHOYP_LOC100708199.1.6,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp144597_c0_seq5,2594,44.8728,0.62999805,0,7,,3.00E-23,P23074,Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (p42In)],Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)],GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0030430; GO:0042025; GO:0046872; GO:0090305; GO:0006508; GO:0004523; GO:0046718; GO:0075732; GO:0019012,DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; host cell cytoplasm; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; viral entry into host cell; viral penetration into host nucleus; virion,PF00075;PF00665;PF00078;PF03539;,6.00E-18,CHOYP_LOC100330808.1.2,,,,,,,POL_SFV1,Simian foamy virus type 1 (SFVmac) (SFV-1),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] comp144597_c0_seq6,1368,45.7602,0.6008986,0,0,,,,,,,,,1.00E-11,CHOYP_LOC100708199.6.6,,,,,,,,, comp144597_c0_seq7,7183,42.2665,0.51802105,1,4,,3.00E-77,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,5.00E-37,CHOYP_LOC100708199.1.6,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp144597_c0_seq8,1315,48.8213,0.62610724,0,0,,,,,,,,,3.00E-30,CHOYP_LOC100330808.2.2,,,,,,,,, comp144599_c0_seq1,6348,41.2413,0.34952889,308,317,,7.00E-50,Q99MV1,Tudor domain-containing protein 1,Tudor domain-containing protein 1,GO:0043046; GO:0033391; GO:0031047; GO:0007281; GO:0007126; GO:0046872; GO:0007275; GO:0071546; GO:0034587; GO:0007283,DNA methylation involved in gamete generation; chromatoid body; gene silencing by RNA; germ cell development; meiosis; metal ion binding; multicellular organismal development; pi-body; piRNA metabolic process; spermatogenesis,PF00567;PF01753;,,,,,,,,,TDRD1_MOUSE,Mus musculus (Mouse),DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283] comp144599_c0_seq2,318,48.4277,0.3959259,21,112,,2.00E-24,Q04832,DNA-binding protein HEXBP (Hexamer-binding protein),DNA-binding protein HEXBP (Hexamer-binding protein),GO:0003677; GO:0005634; GO:0008270,DNA binding; nucleus; zinc ion binding,PF00098;,,,,,,,,,HEXP_LEIMA,Leishmania major, comp144599_c0_seq3,5357,41.8518,0.35707305,9,0,,4.00E-25,P25823,Maternal protein tudor,Maternal protein tudor,GO:0043186; GO:0030719; GO:0008298; GO:0019090; GO:0005739; GO:0005634; GO:0007277,P granule; P granule organization; intracellular mRNA localization; mitochondrial rRNA export from mitochondrion; mitochondrion; nucleus; pole cell development,PF00567;,,,,,,,,,TUD_DROME,Drosophila melanogaster (Fruit fly),germ cell development [GO:0007281]; intracellular mRNA localization [GO:0008298]; mitochondrial rRNA export from mitochondrion [GO:0019090]; P granule organization [GO:0030719]; pole cell development [GO:0007277]; pole cell fate determination [GO:0007278]; pole plasm assembly [GO:0007315] comp144600_c0_seq1,6578,34.2961,0.23503611,0,0,,5.00E-15,P70281,Synaptonemal complex protein 3 (SCP-3),Synaptonemal complex protein 3 (SCP-3),GO:0003677; GO:0051301; GO:0051026; GO:0051309; GO:0007066; GO:0000800; GO:0001673; GO:0007067; GO:0043066; GO:0005654; GO:0015979; GO:0007283; GO:0007130; GO:0000802,DNA binding; cell division; chiasma assembly; female meiosis chromosome separation; female meiosis sister chromatid cohesion; lateral element; male germ cell nucleus; mitosis; negative regulation of apoptotic process; nucleoplasm; photosynthesis; spermatogenesis; synaptonemal complex assembly; transverse filament,PF04803;,,,,,,,,,SYCP3_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; chiasma assembly [GO:0051026]; female meiosis chromosome segregation [GO:0016321]; female meiosis chromosome separation [GO:0051309]; female meiosis sister chromatid cohesion [GO:0007066]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; meiotic nuclear division [GO:0007126]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; spermatogenesis [GO:0007283]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; sperm chromatin condensation [GO:0035092]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]" comp144600_c0_seq2,7394,35.0555,0.24910148,6,0,,9.00E-32,Q5T4T6,Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145),Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145),GO:0005634,nucleus,,,,,,,,,,SYC2L_HUMAN,Homo sapiens (Human), comp144600_c0_seq3,6557,34.2687,0.23083385,0,0,,5.00E-15,P70281,Synaptonemal complex protein 3 (SCP-3),Synaptonemal complex protein 3 (SCP-3),GO:0003677; GO:0051301; GO:0051026; GO:0051309; GO:0007066; GO:0000800; GO:0001673; GO:0007067; GO:0043066; GO:0005654; GO:0015979; GO:0007283; GO:0007130; GO:0000802,DNA binding; cell division; chiasma assembly; female meiosis chromosome separation; female meiosis sister chromatid cohesion; lateral element; male germ cell nucleus; mitosis; negative regulation of apoptotic process; nucleoplasm; photosynthesis; spermatogenesis; synaptonemal complex assembly; transverse filament,PF04803;,,,,,,,,,SYCP3_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; chiasma assembly [GO:0051026]; female meiosis chromosome segregation [GO:0016321]; female meiosis chromosome separation [GO:0051309]; female meiosis sister chromatid cohesion [GO:0007066]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; meiotic nuclear division [GO:0007126]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; spermatogenesis [GO:0007283]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; sperm chromatin condensation [GO:0035092]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]" comp144600_c0_seq5,6666,34.3984,0.24582465,37,0,,2.00E-14,Q90WN7,Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein),Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein),GO:0005730,nucleolus,,,,,,,,,,SYC2L_XENLA,Xenopus laevis (African clawed frog), comp144600_c0_seq7,7373,35.0468,0.24533387,12,0,,3.00E-32,Q5T4T6,Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145),Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145),GO:0005634,nucleus,,,,,,,,,,SYC2L_HUMAN,Homo sapiens (Human), comp144600_c0_seq8,6645,34.3567,0.24713747,6,0,,5.00E-15,P70281,Synaptonemal complex protein 3 (SCP-3),Synaptonemal complex protein 3 (SCP-3),GO:0003677; GO:0051301; GO:0051026; GO:0051309; GO:0007066; GO:0000800; GO:0001673; GO:0007067; GO:0043066; GO:0005654; GO:0015979; GO:0007283; GO:0007130; GO:0000802,DNA binding; cell division; chiasma assembly; female meiosis chromosome separation; female meiosis sister chromatid cohesion; lateral element; male germ cell nucleus; mitosis; negative regulation of apoptotic process; nucleoplasm; photosynthesis; spermatogenesis; synaptonemal complex assembly; transverse filament,PF04803;,,,,,,,,,SYCP3_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; chiasma assembly [GO:0051026]; female meiosis chromosome segregation [GO:0016321]; female meiosis chromosome separation [GO:0051309]; female meiosis sister chromatid cohesion [GO:0007066]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; meiotic nuclear division [GO:0007126]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; spermatogenesis [GO:0007283]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; sperm chromatin condensation [GO:0035092]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]" comp144601_c0_seq1,4758,42.4128,0.58721771,29,12,,2.00E-83,O58451,Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase),Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase),GO:0044205; GO:0006207; GO:0016597; GO:0004070; GO:0006520,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; amino acid binding; aspartate carbamoyltransferase activity; cellular amino acid metabolic process,PF00185;PF02729;,0,CHOYP_PYR1.1.1,,,,,,,PYRB_PYRHO,Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520] comp144601_c0_seq2,8409,44.2026,0.6217506,677,277,,0,Q91437,CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],GO:0044205; GO:0006207; GO:0005524; GO:0016597; GO:0004070; GO:0070409; GO:0004088; GO:0005737; GO:0004151; GO:0006543; GO:0046872,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; ATP binding; amino acid binding; aspartate carbamoyltransferase activity; carbamoyl phosphate biosynthetic process; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; cytoplasm; dihydroorotase activity; glutamine catabolic process; metal ion binding,PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;,0,CHOYP_PYR1.1.1,,,,,,,PYR1_SQUAC,Squalus acanthias (Spiny dogfish),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541] comp144601_c0_seq3,5930,43.4907,0.58969489,0,0,,0,Q91437,CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],GO:0044205; GO:0006207; GO:0005524; GO:0016597; GO:0004070; GO:0070409; GO:0004088; GO:0005737; GO:0004151; GO:0006543; GO:0046872,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; ATP binding; amino acid binding; aspartate carbamoyltransferase activity; carbamoyl phosphate biosynthetic process; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; cytoplasm; dihydroorotase activity; glutamine catabolic process; metal ion binding,PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;,0,CHOYP_PYR1.1.1,,,,,,,PYR1_SQUAC,Squalus acanthias (Spiny dogfish),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541] comp144601_c0_seq6,4727,42.564,0.59126574,0,0,,2.00E-83,O58451,Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase),Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase),GO:0044205; GO:0006207; GO:0016597; GO:0004070; GO:0006520,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; amino acid binding; aspartate carbamoyltransferase activity; cellular amino acid metabolic process,PF00185;PF02729;,,,2.00E-30,ruditapes_c12674,,,,,PYRB_PYRHO,Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520] comp144602_c0_seq1,4195,46.1502,0.48941024,17,0,,,,,,,,,0,CHOYP_CEP290.1.1,,,,,,,,, comp144602_c0_seq10,344,46.5116,0.82143551,0,0,,9.00E-09,O15078,Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2),Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2),GO:0000086; GO:0036038; GO:0009986; GO:0005813; GO:0042384; GO:0005829; GO:0007163; GO:0042462; GO:0030902; GO:0005932; GO:0005634; GO:0030916; GO:0032391; GO:0045893; GO:0048793; GO:0015031; GO:0030814; GO:0060041,"G2/M transition of mitotic cell cycle; TCTN-B9D complex; cell surface; centrosome; cilium assembly; cytosol; establishment or maintenance of cell polarity; eye photoreceptor cell development; hindbrain development; microtubule basal body; nucleus; otic vesicle formation; photoreceptor connecting cilium; positive regulation of transcription, DNA-dependent; pronephros development; protein transport; regulation of cAMP metabolic process; retina development in camera-type eye",PF16574;,,,,,,,,,CE290_HUMAN,Homo sapiens (Human),"cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; eye photoreceptor cell development [GO:0042462]; G2/M transition of mitotic cell cycle [GO:0000086]; hindbrain development [GO:0030902]; otic vesicle formation [GO:0030916]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201]" comp144602_c0_seq2,5478,45.1807,0.49048237,0,16,,0,O15078,Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2),Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2),GO:0000086; GO:0036038; GO:0009986; GO:0005813; GO:0042384; GO:0005829; GO:0007163; GO:0042462; GO:0030902; GO:0005932; GO:0005634; GO:0030916; GO:0032391; GO:0045893; GO:0048793; GO:0015031; GO:0030814; GO:0060041,"G2/M transition of mitotic cell cycle; TCTN-B9D complex; cell surface; centrosome; cilium assembly; cytosol; establishment or maintenance of cell polarity; eye photoreceptor cell development; hindbrain development; microtubule basal body; nucleus; otic vesicle formation; photoreceptor connecting cilium; positive regulation of transcription, DNA-dependent; pronephros development; protein transport; regulation of cAMP metabolic process; retina development in camera-type eye",PF16574;,,,,,,,,,CE290_HUMAN,Homo sapiens (Human),"cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; eye photoreceptor cell development [GO:0042462]; G2/M transition of mitotic cell cycle [GO:0000086]; hindbrain development [GO:0030902]; otic vesicle formation [GO:0030916]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201]" comp144602_c0_seq4,6501,42.7011,0.49265383,365,409,,0,O15078,Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2),Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2),GO:0000086; GO:0036038; GO:0009986; GO:0005813; GO:0042384; GO:0005829; GO:0007163; GO:0042462; GO:0030902; GO:0005932; GO:0005634; GO:0030916; GO:0032391; GO:0045893; GO:0048793; GO:0015031; GO:0030814; GO:0060041,"G2/M transition of mitotic cell cycle; TCTN-B9D complex; cell surface; centrosome; cilium assembly; cytosol; establishment or maintenance of cell polarity; eye photoreceptor cell development; hindbrain development; microtubule basal body; nucleus; otic vesicle formation; photoreceptor connecting cilium; positive regulation of transcription, DNA-dependent; pronephros development; protein transport; regulation of cAMP metabolic process; retina development in camera-type eye",PF16574;,0,CHOYP_CEP290.1.1,,,,,,,CE290_HUMAN,Homo sapiens (Human),"cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; eye photoreceptor cell development [GO:0042462]; G2/M transition of mitotic cell cycle [GO:0000086]; hindbrain development [GO:0030902]; otic vesicle formation [GO:0030916]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201]" comp144603_c0_seq2,8461,36.225,0.59424573,21,15,,4.00E-24,Q99MU0,Protein DBF4 homolog A (ChDBF4),Protein DBF4 homolog A (ChDBF4),GO:0006260; GO:0003993; GO:0007049; GO:0003676; GO:0005634; GO:0008270,DNA replication; acid phosphatase activity; cell cycle; nucleic acid binding; nucleus; zinc ion binding,PF07535;,,,,,,,,,DBF4A_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),cell cycle [GO:0007049]; DNA replication [GO:0006260] comp144604_c0_seq1,13787,43.7078,0.57082106,10784,242,,0,Q8WXX0,"Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2)","Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0005509; GO:0001539; GO:0005929; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; calcium ion binding; ciliary or bacterial-type flagellar motility; cilium; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,0,CHOYP_DNAH7.2.2,3.00E-47,ruditapes_c22262,,,,,DYH7_HUMAN,Homo sapiens (Human),cilium movement [GO:0003341]; cilium or flagellum-dependent cell motility [GO:0001539]; inner dynein arm assembly [GO:0036159] comp144604_c0_seq2,2697,33.5187,0.62201585,904,79,,6.00E-130,Q63170,"Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)","Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0005509; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; calcium ion binding; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,6.00E-113,CHOYP_DNAH7.2.2,,,,,,,DYH7_RAT,Rattus norvegicus (Rat),cilium movement [GO:0003341] comp144605_c0_seq1,7655,42.4428,0.44463576,29,39,,0,Q99PV0,Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8),Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8),GO:0030623; GO:0017070; GO:0071013; GO:0000398; GO:0016607,"U5 snRNA binding; U6 snRNA binding; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nuclear speck",PF01398;PF08082;PF08083;PF08084;PF12134;PF10598;PF10597;PF10596;,0,CHOYP_PRP8.1.1,,,,,,,PRP8_MOUSE,Mus musculus (Mouse),"cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp144605_c0_seq2,7956,42.1569,0.45062596,225,744,,0,Q6P2Q9,Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220),Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220),GO:0030623; GO:0005682; GO:0017070; GO:0071013; GO:0000398; GO:0016607; GO:0005654,"U5 snRNA binding; U5 snRNP; U6 snRNA binding; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nuclear speck; nucleoplasm",PF01398;PF08082;PF08083;PF08084;PF12134;PF10598;PF10597;PF10596;,0,CHOYP_PRP8.1.1,,,,,,,PRP8_HUMAN,Homo sapiens (Human),"cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]" comp144606_c0_seq1,3881,47.3074,0.55486502,375,168,,1.00E-59,Q9JI18,Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),GO:0005509; GO:0016021; GO:0050750; GO:0005041; GO:0016020,calcium ion binding; integral to membrane; low-density lipoprotein particle receptor binding; low-density lipoprotein receptor activity; membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1B_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701] comp144606_c0_seq3,1747,49.7424,0.55070687,0,6,,7.00E-63,Q9JI18,Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),GO:0005509; GO:0016021; GO:0050750; GO:0005041; GO:0016020,calcium ion binding; integral to membrane; low-density lipoprotein particle receptor binding; low-density lipoprotein receptor activity; membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1B_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701] comp144606_c1_seq1,1435,46.4111,0.57207039,0,3,,1.00E-44,A2ASQ1,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0005796; GO:0030548; GO:0005605; GO:0005509; GO:0030154; GO:0030054; GO:0009986; GO:0035374; GO:0002162; GO:0005615; GO:0043395; GO:0016021; GO:0007275; GO:0007528; GO:0045213; GO:0005886; GO:0007009; GO:0032321; GO:0051491; GO:0043525; GO:2000541; GO:0001934; GO:0045887; GO:0045944; GO:0043113; GO:0032314; GO:0033691; GO:0045202,Golgi lumen; acetylcholine receptor regulator activity; basal lamina; calcium ion binding; cell differentiation; cell junction; cell surface; chondroitin sulfate binding; dystroglycan binding; extracellular space; heparan sulfate proteoglycan binding; integral to membrane; multicellular organismal development; neuromuscular junction development; neurotransmitter receptor metabolic process; plasma membrane; plasma membrane organization; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of neuron apoptotic process; positive regulation of protein geranylgeranylation; positive regulation of protein phosphorylation; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; regulation of Rac GTPase activity; sialic acid binding; synapse,PF00008;PF00050;PF07648;PF00053;PF00054;PF01390;,,,,,,,,,AGRIN_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; glycosaminoglycan biosynthetic process [GO:0006024]; multicellular organism development [GO:0007275]; negative regulation of sodium:potassium-exchanging ATPase activity [GO:1903407]; negative regulation of sodium ion export from cell [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of synaptic growth at neuromuscular junction [GO:0008582] comp144606_c1_seq2,3244,49.3218,0.51860132,556,258,,0,P98160,Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide],Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide],GO:0005796; GO:0001525; GO:0005605; GO:0007420; GO:0005975; GO:0048738; GO:0060351; GO:0002062; GO:0030204; GO:0048704; GO:0001958; GO:0030198; GO:0005615; GO:0070062; GO:0006024; GO:0006027; GO:0042157; GO:0043202; GO:0046872; GO:0007603; GO:0005886; GO:0008104; GO:0001523,"Golgi lumen; angiogenesis; basal lamina; brain development; carbohydrate metabolic process; cardiac muscle tissue development; cartilage development involved in endochondral bone morphogenesis; chondrocyte differentiation; chondroitin sulfate metabolic process; embryonic skeletal system morphogenesis; endochondral ossification; extracellular matrix organization; extracellular space; extracellular vesicular exosome; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; lipoprotein metabolic process; lysosomal lumen; metal ion binding; phototransduction, visible light; plasma membrane; protein localization; retinoid metabolic process",PF00008;PF12661;PF07679;PF13895;PF00052;PF00053;PF00054;PF00057;,5.00E-70,CHOYP_HSPG2.1.4,,,,,,,PGBM_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; lipoprotein metabolic process [GO:0042157]; retinoid metabolic process [GO:0001523] comp144606_c1_seq4,2392,49.2893,0.56775409,590,278,,2.00E-33,A2AJ76,Hemicentin-2,Hemicentin-2,GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus,PF12662;PF07645;PF07474;PF07679;,,,,,,,,,HMCN2_MOUSE,Mus musculus (Mouse),response to stimulus [GO:0050896] comp144606_c1_seq5,939,48.0298,0.59748995,0,0,,1.00E-13,P25391,Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),GO:0007411; GO:0060445; GO:0007155; GO:0007166; GO:0005911; GO:0060441; GO:0045198; GO:0030198; GO:0005201; GO:0005615; GO:0043208; GO:0005606; GO:0005608; GO:0002011; GO:0030155; GO:0030334; GO:0045995; GO:0061304,axon guidance; branching involved in salivary gland morphogenesis; cell adhesion; cell surface receptor signaling pathway; cell-cell junction; epithelial tube branching involved in lung morphogenesis; establishment of epithelial cell apical/basal polarity; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; glycosphingolipid binding; laminin-1 complex; laminin-3 complex; morphogenesis of an epithelial sheet; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; retinal blood vessel morphogenesis,PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;,,,,,,,,,LAMA1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995] comp144606_c1_seq6,1603,49.4697,0.57967446,405,180,,5.00E-50,A2AJ76,Hemicentin-2,Hemicentin-2,GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus,PF12662;PF07645;PF07474;PF07679;,,,,,,,,,HMCN2_MOUSE,Mus musculus (Mouse),response to stimulus [GO:0050896] comp144606_c1_seq7,2749,44.6708,0.5438458,188,344,,3.00E-154,P98160,Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide],Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide],GO:0005796; GO:0001525; GO:0005605; GO:0007420; GO:0005975; GO:0048738; GO:0060351; GO:0002062; GO:0030204; GO:0048704; GO:0001958; GO:0030198; GO:0005615; GO:0070062; GO:0006024; GO:0006027; GO:0042157; GO:0043202; GO:0046872; GO:0007603; GO:0005886; GO:0008104; GO:0001523,"Golgi lumen; angiogenesis; basal lamina; brain development; carbohydrate metabolic process; cardiac muscle tissue development; cartilage development involved in endochondral bone morphogenesis; chondrocyte differentiation; chondroitin sulfate metabolic process; embryonic skeletal system morphogenesis; endochondral ossification; extracellular matrix organization; extracellular space; extracellular vesicular exosome; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; lipoprotein metabolic process; lysosomal lumen; metal ion binding; phototransduction, visible light; plasma membrane; protein localization; retinoid metabolic process",PF00008;PF12661;PF07679;PF13895;PF00052;PF00053;PF00054;PF00057;,1.00E-39,CHOYP_HSPG2.1.4,,,,,,,PGBM_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; lipoprotein metabolic process [GO:0042157]; retinoid metabolic process [GO:0001523] comp144607_c0_seq1,6797,46.2557,0.45950876,1353,145,,1.00E-59,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,0,CHOYP_LOC100376274.4.7,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144607_c0_seq3,1755,48.8319,0.46861876,0,0,,7.00E-25,Q9MBF8,"Dynein-1-beta heavy chain, flagellar inner arm I1 complex (1-beta DHC) (Dynein-1, subspecies f)","Dynein-1-beta heavy chain, flagellar inner arm I1 complex (1-beta DHC) (Dynein-1, subspecies f)",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,7.00E-66,CHOYP_LOC100376274.2.7,,,,,,,DYH1B_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159] comp144607_c0_seq4,4202,46.7634,0.45820254,2,0,,4.00E-30,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,7.00E-146,CHOYP_LOC100376274.7.7,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144607_c0_seq6,7785,46.0244,0.46193287,624,43,,5.00E-60,Q96M86,Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35),Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35),GO:0030031; GO:0001539; GO:0030286; GO:0003777; GO:0007018,cell projection assembly; ciliary or bacterial-type flagellar motility; dynein complex; microtubule motor activity; microtubule-based movement,PF08393;PF03028;PF12777;,0,CHOYP_LOC100376274.4.7,,,,,,,DNHD1_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144607_c0_seq7,2160,48.2407,0.46175053,53,1,,7.00E-31,Q9C0G6,"Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)","Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,6.00E-74,CHOYP_LOC100376274.7.7,,,,,,,DYH6_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp144608_c0_seq1,3597,38.0595,0.50013904,50,5,,4.00E-51,Q4GZT3,Polycystin-2 (Polycystic kidney disease 2 protein homolog),Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2),GO:0007259; GO:0035904; GO:0045180; GO:0009925; GO:0001658; GO:0005262; GO:0005509; GO:0048763; GO:0007050; GO:0005911; GO:0071498; GO:0071464; GO:0071470; GO:0042994; GO:0050982; GO:0003127; GO:0071910; GO:0001892; GO:0031941; GO:0001947; GO:0071458; GO:0071556; GO:0005887; GO:0030027; GO:0016020; GO:0072177; GO:0072284; GO:0072218; GO:0072214; GO:0072219; GO:0072235; GO:0072075; GO:0035502; GO:0072208; GO:0005932; GO:0072686; GO:0031512; GO:2000134; GO:0060315; GO:0021915; GO:0031513; GO:0060674; GO:0002133; GO:0071158; GO:0031659; GO:0031587; GO:0045429; GO:0045944; GO:0005267; GO:0030814; GO:0090279; GO:0042127; GO:0051209; GO:0061441; GO:0061333; GO:0021510; GO:0005245; GO:0005248,"JAK-STAT cascade; aorta development; basal cortex; basal plasma membrane; branching involved in ureteric bud morphogenesis; calcium channel activity; calcium ion binding; calcium-induced calcium release activity; cell cycle arrest; cell-cell junction; cellular response to fluid shear stress; cellular response to hydrostatic pressure; cellular response to osmotic stress; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; detection of nodal flow; determination of liver left/right asymmetry; embryonic placenta development; filamentous actin; heart looping; integral to cytosolic side of endoplasmic reticulum membrane; integral to lumenal side of endoplasmic reticulum membrane; integral to plasma membrane; lamellipodium; membrane; mesonephric duct development; metanephric S-shaped body morphogenesis; metanephric ascending thin limb development; metanephric cortex development; metanephric cortical collecting duct development; metanephric distal tubule development; metanephric mesenchyme development; metanephric part of ureteric bud development; metanephric smooth muscle tissue development; microtubule basal body; mitotic spindle; motile primary cilium; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of ryanodine-sensitive calcium-release channel activity; neural tube development; nonmotile primary cilium; placenta blood vessel development; polycystin complex; positive regulation of cell cycle arrest; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; positive regulation of nitric oxide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; potassium channel activity; regulation of cAMP metabolic process; regulation of calcium ion import; regulation of cell proliferation; release of sequestered calcium ion into cytosol; renal artery morphogenesis; renal tubule morphogenesis; spinal cord development; voltage-gated calcium channel activity; voltage-gated sodium channel activity",PF08016;,5.00E-14,CHOYP_TRIADDRAFT_53596.1.1,,,,,,,PKD2_BOVIN,Bos taurus (Bovine),"aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]" comp144608_c0_seq3,7890,39.2776,0.45948171,1803,140,,1.00E-79,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp144609_c0_seq1,17305,45.7267,0.47654562,5623,25,,0,Q4G0P3,Hydrocephalus-inducing protein homolog,Hydrocephalus-inducing protein homolog,,,PF15780;,0,CHOYP_LOC100375784.4.6,,,,,,,HYDIN_HUMAN,Homo sapiens (Human),axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] comp144609_c0_seq2,10483,45.073,0.47833227,370,14,,0,Q4G0P3,Hydrocephalus-inducing protein homolog,Hydrocephalus-inducing protein homolog,,,PF15780;,0,CHOYP_LOC100375784.2.6,1.00E-114,ruditapes_c17645,,,,,HYDIN_HUMAN,Homo sapiens (Human),axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] comp144610_c0_seq1,3406,42.2196,0.3767073,55,50,,8.00E-164,P49793,Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)],Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)],GO:0006260; GO:0000776; GO:0051028; GO:0042405; GO:0031965; GO:0034399; GO:0051292; GO:0044615; GO:0031080; GO:0005654; GO:0042277; GO:0000059; GO:0017056,"DNA replication; kinetochore; mRNA transport; nuclear inclusion body; nuclear membrane; nuclear periphery; nuclear pore complex assembly; nuclear pore nuclear basket; nuclear pore outer ring; nucleoplasm; peptide binding; protein import into nucleus, docking; structural constituent of nuclear pore",PF04096;PF12110;,2.00E-11,CHOYP_NUP98.1.1,,,,,,,NUP98_RAT,Rattus norvegicus (Rat),"DNA replication [GO:0006260]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus, docking [GO:0000059]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398]" comp144610_c0_seq2,5612,44.9038,0.42247346,646,850,,2.00E-36,G5EEH9,Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (CeNup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (CeNup96)],Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (CeNup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (CeNup96)],GO:0043186; GO:0030719; GO:0003723; GO:0009792; GO:0051028; GO:0031965; GO:0005643; GO:0015031,P granule; P granule organization; RNA binding; embryo development ending in birth or egg hatching; mRNA transport; nuclear membrane; nuclear pore; protein transport,PF04096;PF13634;PF12110;,2.00E-53,CHOYP_NUP98.1.1,,,,,,,NUP98_CAEEL,Caenorhabditis elegans,embryo development ending in birth or egg hatching [GO:0009792]; mRNA transport [GO:0051028]; P granule organization [GO:0030719]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398] comp144611_c0_seq1,6890,40.8273,0.56787034,0,0,,0,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,1.00E-106,CHOYP_LRP2.6.7,,,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp144611_c0_seq10,6417,40.4862,0.56993405,0,0,,4.00E-107,O88307,Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),GO:0005794; GO:0008203; GO:0006897; GO:0005768; GO:0016021; GO:0006869; GO:0034362; GO:0030169; GO:0007275; GO:0048471,Golgi apparatus; cholesterol metabolic process; endocytosis; endosome; integral to membrane; lipid transport; low-density lipoprotein particle; low-density lipoprotein particle binding; multicellular organismal development; perinuclear region of cytoplasm,PF00041;PF00057;PF00058;PF15902;PF15901;,,,,,,,,,SORL_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910] comp144611_c0_seq11,332,44.2771,0.37027764,0,0,,4.00E-27,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,,,,,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp144611_c0_seq2,6399,40.4751,0.57179638,0,0,,4.00E-107,O88307,Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA),GO:0005794; GO:0008203; GO:0006897; GO:0005768; GO:0016021; GO:0006869; GO:0034362; GO:0030169; GO:0007275; GO:0048471,Golgi apparatus; cholesterol metabolic process; endocytosis; endosome; integral to membrane; lipid transport; low-density lipoprotein particle; low-density lipoprotein particle binding; multicellular organismal development; perinuclear region of cytoplasm,PF00041;PF00057;PF00058;PF15902;PF15901;,1.00E-106,CHOYP_LRP2.6.7,,,,,,,SORL_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910] comp144611_c0_seq3,7570,41.3606,0.55511647,0,0,,0,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,8.00E-98,CHOYP_PHUM_PHUM470230.1.1,,,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp144611_c0_seq4,12781,42.6492,0.50754322,4,0,,0,A2ARV4,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008283; GO:0005905; GO:0030139; GO:0005783; GO:0005768; GO:0030900; GO:0016021; GO:0004872; GO:0006898; GO:0006766,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cell proliferation; coated pit; endocytic vesicle; endoplasmic reticulum; endosome; forebrain development; integral to membrane; receptor activity; receptor-mediated endocytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,3.00E-105,CHOYP_LRP2.6.7,,,,,,,LRP2_MOUSE,Mus musculus (Mouse),aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; forebrain development [GO:0030900]; heart development [GO:0007507]; receptor-mediated endocytosis [GO:0006898]; ventricular septum development [GO:0003281]; vitamin metabolic process [GO:0006766] comp144611_c0_seq5,14339,42.5832,0.49900202,84,29,,0,A2ARV4,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008283; GO:0005905; GO:0030139; GO:0005783; GO:0005768; GO:0030900; GO:0016021; GO:0004872; GO:0006898; GO:0006766,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cell proliferation; coated pit; endocytic vesicle; endoplasmic reticulum; endosome; forebrain development; integral to membrane; receptor activity; receptor-mediated endocytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,7.00E-108,CHOYP_LRP2.6.7,,,,,,,LRP2_MOUSE,Mus musculus (Mouse),aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; forebrain development [GO:0030900]; heart development [GO:0007507]; receptor-mediated endocytosis [GO:0006898]; ventricular septum development [GO:0003281]; vitamin metabolic process [GO:0006766] comp144611_c0_seq6,13638,42.6822,0.50263437,0,14,,0,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,7.00E-108,CHOYP_LRP2.6.7,3.00E-15,ruditapes_c17767,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp144611_c0_seq7,2291,44.2601,0.4274627,3,0,,2.00E-84,O88572,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0090245; GO:0046849; GO:0060444; GO:0061310; GO:0061324; GO:0005901; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0060026; GO:0015026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0051593; GO:0048705; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; axis elongation involved in somitogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; caveola; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; convergent extension; coreceptor activity; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; response to folic acid; skeletal system morphogenesis; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,,,,,,,,,LRP6_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp144611_c0_seq9,6908,40.8367,0.5661798,0,0,,0,P98158,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0007568; GO:0016324; GO:0031526; GO:0005509; GO:0005905; GO:0016197; GO:0005768; GO:0005615; GO:0030492; GO:0020028; GO:0046879; GO:0016021; GO:0042953; GO:0045121; GO:0010951; GO:0031100; GO:0043234; GO:0004872; GO:0006898; GO:0010165; GO:0042493; GO:0032526; GO:0033280; GO:0045056; GO:0006766,aging; apical plasma membrane; brush border membrane; calcium ion binding; coated pit; endosomal transport; endosome; extracellular space; hemoglobin binding; hemoglobin import; hormone secretion; integral to membrane; lipoprotein transport; membrane raft; negative regulation of endopeptidase activity; organ regeneration; protein complex; receptor activity; receptor-mediated endocytosis; response to X-ray; response to drug; response to retinoic acid; response to vitamin D; transcytosis; vitamin metabolic process,PF12662;PF07645;PF00057;PF00058;,1.00E-106,CHOYP_LRP2.6.7,,,,,,,LRP2_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766] comp144612_c0_seq1,15409,46.3301,0.3707226,86,0,,7.00E-99,Q39565,"Dynein beta chain, flagellar outer arm","Dynein beta chain, flagellar outer arm",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_BRAFLDRAFT_108792.1.5,,,,,,,DYHB_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp144612_c0_seq2,15274,46.2485,0.36666375,50,2,,7.00E-99,Q39565,"Dynein beta chain, flagellar outer arm","Dynein beta chain, flagellar outer arm",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_BRAFLDRAFT_108792.1.5,,,,,,,DYHB_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp144612_c0_seq3,1582,45.0695,0.48826359,234,4,,5.00E-40,Q39565,"Dynein beta chain, flagellar outer arm","Dynein beta chain, flagellar outer arm",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_BRAFLDRAFT_108792.2.5,,,,,,,DYHB_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp144613_c0_seq2,1981,35.2852,0.78127638,320,515,,5.00E-17,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp144613_c0_seq5,1231,36.3119,0.89113983,565,1024,,2.00E-08,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp144613_c0_seq8,2126,39.6049,0.75871399,370,463,,2.00E-07,P21330,Nucleic-acid-binding protein from mobile element jockey (ORF1),Nucleic-acid-binding protein from mobile element jockey (ORF1),GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,PF07530;,,,,,,,,,GAGJ_DROME,Drosophila melanogaster (Fruit fly), comp144614_c0_seq1,10040,47.5797,0.51014123,19,0,,2.00E-135,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_TRIADDRAFT_56463.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp144614_c0_seq10,4042,40.3266,0.55455274,1252,203,,3.00E-34,Q8IVF4,"Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)","Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,7.00E-13,CHOYP_LOC100374716.1.1,,,,,,,DYH10_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp144614_c0_seq2,9993,47.5433,0.50777741,8,8,,2.00E-135,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_TRIADDRAFT_56463.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp144614_c0_seq3,8075,47.2074,0.50238322,0,0,,,,,,,,,0,CHOYP_TRIADDRAFT_56463.1.2,,,,,,,,, comp144614_c0_seq4,3180,44.4654,0.53684209,47,0,,,,,,,,,3.00E-168,CHOYP_LOC577805.4.4,,,,,,,,, comp144614_c0_seq5,8028,47.1973,0.50534289,0,0,,2.00E-135,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_LOC577805.1.4,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp144614_c0_seq6,7859,47.2325,0.50128622,0,0,,4.00E-99,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_TRIADDRAFT_56463.1.2,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp144614_c0_seq8,6760,47.0858,0.48843013,0,0,,4.00E-136,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_TRIADDRAFT_56463.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp144614_c0_seq9,3046,44.0578,0.53130504,0,0,,3.00E-43,Q39575,"Dynein gamma chain, flagellar outer arm","Dynein gamma chain, flagellar outer arm",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-142,CHOYP_LOC577805.4.4,,,,,,,DYHG_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158] comp144617_c0_seq1,840,37.619,0.6484993,68978,127967,,8.00E-47,Q3T0B7,40S ribosomal protein S27-like,40S ribosomal protein S27-like,GO:0046872; GO:0005840; GO:0003735; GO:0006412,metal ion binding; ribosome; structural constituent of ribosome; translation,PF01667;,5.00E-51,CHOYP_LACH.1.1,7.00E-72,ruditapes_lrc34958,,,,,RS27L_BOVIN,Bos taurus (Bovine),ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] comp144618_c0_seq1,583,42.1955,0.54131515,90359,185950,,1.00E-74,P79781,Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a],Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a],GO:0002755; GO:0035419; GO:0007250; GO:0022627; GO:0045087; GO:0046872; GO:0005654; GO:0003735; GO:0035681; GO:0034134; GO:0035682; GO:0034138; GO:0034142; GO:0034146; GO:0034154; GO:0006412; GO:0019985,MyD88-dependent toll-like receptor signaling pathway; activation of MAPK activity involved in innate immune response; activation of NF-kappaB-inducing kinase activity; cytosolic small ribosomal subunit; innate immune response; metal ion binding; nucleoplasm; structural constituent of ribosome; toll-like receptor 15 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 21 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 7 signaling pathway; translation; translesion synthesis,PF01599;PF00240;,8.00E-148,CHOYP_ABCF2.1.2,8.00E-152,ruditapes_lrc33929,,,,,RS27A_CHICK,Gallus gallus (Chicken),DNA repair [GO:0006281]; translation [GO:0006412]; translesion synthesis [GO:0019985] comp144619_c0_seq1,1344,47.0982,0.57892925,68398,298636,,0,P39872,60S ribosomal protein L3,60S ribosomal protein L3,GO:0005730; GO:0005840; GO:0003735; GO:0006412,nucleolus; ribosome; structural constituent of ribosome; translation,PF00297;,0,CHOYP_LOC660560.2.4,0,ruditapes2_c160,,,,,RL3_BOVIN,Bos taurus (Bovine),ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp144621_c0_seq1,625,40.96,0.4613129,31289,84166,,3.00E-92,P62278,40S ribosomal protein S13,40S ribosomal protein S13,GO:0022627; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; structural constituent of ribosome; translation,PF08069;PF00312;,2.00E-118,CHOYP_RS13.3.5,1.00E-149,ruditapes_lrc33726,,,,,RS13_RAT,Rattus norvegicus (Rat),translation [GO:0006412] comp144622_c0_seq1,386,36.0104,0.40996038,21603,33878,,3.00E-40,Q6AZJ9,40S ribosomal protein S21,40S ribosomal protein S21,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01249;,1.00E-60,CHOYP_LOC100701551.6.7,1.00E-70,ruditapes2_c773,,,,,RS21_XENLA,Xenopus laevis (African clawed frog),translation [GO:0006412] comp144624_c0_seq1,615,40.3252,0.69259442,12455,25618,,6.00E-27,P43024,"Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver)","Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver)",GO:0004129; GO:0005751; GO:0005739,cytochrome-c oxidase activity; mitochondrial respiratory chain complex IV; mitochondrion,PF02046;,,,,,,,,,CX6A1_MOUSE,Mus musculus (Mouse), comp144625_c0_seq1,1032,37.5969,0.44340753,5306,23326,,5.00E-30,Q24251,"ATP synthase subunit d, mitochondrial (ATPase subunit d)","ATP synthase subunit d, mitochondrial (ATPase subunit d)",GO:0015986; GO:0015078; GO:0005811; GO:0005875; GO:0000276; GO:0005739,"ATP synthesis coupled proton transport; hydrogen ion transmembrane transporter activity; lipid particle; microtubule associated complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrion",,,,2.00E-23,ruditapes2_c32,,,,,ATP5H_DROME,Drosophila melanogaster (Fruit fly),ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; determination of adult lifespan [GO:0008340]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of TOR signaling [GO:0032007]; proton transport [GO:0015992]; regulation of mitochondrial membrane potential [GO:0051881]; response to oxidative stress [GO:0006979] comp144626_c0_seq1,850,40.3529,0.40510087,2224,14600,,9.00E-39,P86229,Keratinocyte-associated protein 2 (KCP-2),Keratinocyte-associated protein 2 (KCP-2),GO:0016021,integral to membrane,PF09775;,6.00E-25,CHOYP_LOC100049762.1.1,5.00E-61,ruditapes2_c795,,,,,KTAP2_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp144629_c0_seq1,727,43.1912,0.65071427,5965,1002,,2.00E-42,P19178,Histone H2A,Histone H2A,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;PF16211;,1.00E-107,CHOYP_CPIPJ_CPIJ012408.1.1,2.00E-78,ruditapes_c1797,3.00E-98,CU686554.p.cg.6,9,,H2A_PLADU,Platynereis dumerilii (Dumeril's clam worm), comp144632_c0_seq1,743,38.0888,0.92990869,532,3956,,2.00E-13,Q7JWG9,"39S ribosomal protein L52, mitochondrial (L52mt) (MRP-L52)","39S ribosomal protein L52, mitochondrial (L52mt) (MRP-L52)",GO:0005762; GO:0003735; GO:0006412,mitochondrial large ribosomal subunit; structural constituent of ribosome; translation,,,,4.00E-17,ruditapes2_c1668,,,,,RM52_DROME,Drosophila melanogaster (Fruit fly),translation [GO:0006412] comp144634_c0_seq1,850,36.9412,0.9048391,0,3985,,1.00E-09,Q9DAK4,Fatty acid-binding protein 12,Fatty acid-binding protein 12,GO:0008289; GO:0005215,lipid binding; transporter activity,PF00061;,,,,,,,,,FBP12_MOUSE,Mus musculus (Mouse), comp144636_c0_seq1,687,37.8457,0.50887682,234,2962,,8.00E-75,Q8BHG2,UPF0587 protein C1orf123 homolog,UPF0587 protein C1orf123 homolog,,,PF05907;,,,,,,,,,CA123_MOUSE,Mus musculus (Mouse), comp144637_c0_seq1,1020,35.3922,0.99126309,101,3105,,2.00E-16,Q0P5Y3,Tubulin polymerization-promoting protein family member 2,Tubulin polymerization-promoting protein family member 2,GO:0005509; GO:0005737,calcium ion binding; cytoplasm,PF05517;,8.00E-18,CHOYP_LOC100564268.1.1,2.00E-106,ruditapes2_c759,,,,,TPPP2_MOUSE,Mus musculus (Mouse), comp144643_c0_seq1,524,36.6412,0.59288753,273,814,,2.00E-16,B4F7A1,Complex III assembly factor LYRM7 (LYR motif-containing protein 7),Complex III assembly factor LYRM7 (LYR motif-containing protein 7),GO:0005759,mitochondrial matrix,PF05347;,,,,,,,,,LYRM7_RAT,Rattus norvegicus (Rat), comp144665_c0_seq1,362,55.2486,0.39946283,70,260,,5.00E-79,P16410,Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152),Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152),GO:0050853; GO:0005794; GO:0031295; GO:0045334; GO:0009897; GO:0006955; GO:0005887; GO:0030889; GO:0045590; GO:0048471; GO:0043065; GO:0006974,B cell receptor signaling pathway; Golgi apparatus; T cell costimulation; clathrin-coated endocytic vesicle; external side of plasma membrane; immune response; integral to plasma membrane; negative regulation of B cell proliferation; negative regulation of regulatory T cell differentiation; perinuclear region of cytoplasm; positive regulation of apoptotic process; response to DNA damage stimulus,PF07686;,,,,,,,,,CTLA4_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of regulatory T cell differentiation [GO:0045590]; positive regulation of apoptotic process [GO:0043065]; T cell costimulation [GO:0031295] comp144688_c0_seq1,322,47.205,0.84822247,17,179,,,,,,,,,2.00E-31,CHOYP_RNA45S5.4.4,,,,,,,,, comp144694_c0_seq1,325,60.6154,0.30910533,28,142,,3.00E-73,P01375,"Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]","Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]",GO:0007254; GO:0000165; GO:0000187; GO:0000185; GO:0006919; GO:0060555; GO:0019722; GO:0001775; GO:0071230; GO:0071316; GO:0002439; GO:0005125; GO:0050830; GO:0048566; GO:0060664; GO:0009897; GO:0030198; GO:0005615; GO:0008625; GO:0006006; GO:0006959; GO:0042802; GO:0005887; GO:0050901; GO:0031663; GO:0045121; GO:0070265; GO:0002037; GO:0010693; GO:0061048; GO:0008285; GO:0002740; GO:2001240; GO:0045599; GO:0046325; GO:0044130; GO:0032715; GO:0050995; GO:0010888; GO:0045668; GO:0043242; GO:0000122; GO:0045071; GO:0009887; GO:0030316; GO:0001891; GO:0070374; GO:0043123; GO:0046330; GO:0043507; GO:0042346; GO:0051092; GO:0051533; GO:0043065; GO:0060559; GO:2000343; GO:0045080; GO:0002876; GO:0050715; GO:0031622; GO:0051798; GO:0034116; GO:0002925; GO:0032729; GO:0032755; GO:0045416; GO:0051044; GO:0045840; GO:0071677; GO:0043525; GO:0045429; GO:0045672; GO:0033138; GO:0071803; GO:0043243; GO:0051897; GO:2000010; GO:0048661; GO:0050806; GO:0045944; GO:0045994; GO:0060557; GO:0000060; GO:0043491; GO:0032800; GO:0055037; GO:0060693; GO:0051023; GO:0050796; GO:0014823; GO:0042493; GO:0051384; GO:0001666; GO:0009612; GO:0009651; GO:0009615; GO:0030730; GO:0003009; GO:0044212; GO:0006927; GO:0005164; GO:0033209,"JNK cascade; MAPK cascade; activation of MAPK activity; activation of MAPKKK activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of necroptosis by extracellular signals; calcium-mediated signaling; cell activation; cellular response to amino acid stimulus; cellular response to nicotine; chronic inflammatory response to antigenic stimulus; cytokine activity; defense response to Gram-positive bacterium; embryonic digestive tract development; epithelial cell proliferation involved in salivary gland morphogenesis; external side of plasma membrane; extracellular matrix organization; extracellular space; extrinsic apoptotic signaling pathway via death domain receptors; glucose metabolic process; humoral immune response; identical protein binding; integral to plasma membrane; leukocyte tethering or rolling; lipopolysaccharide-mediated signaling pathway; membrane raft; necrotic cell death; negative regulation of L-glutamate transport; negative regulation of alkaline phosphatase activity; negative regulation of branching involved in lung morphogenesis; negative regulation of cell proliferation; negative regulation of cytokine secretion involved in immune response; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of fat cell differentiation; negative regulation of glucose import; negative regulation of growth of symbiont in host; negative regulation of interleukin-6 production; negative regulation of lipid catabolic process; negative regulation of lipid storage; negative regulation of osteoblast differentiation; negative regulation of protein complex disassembly; negative regulation of transcription from RNA polymerase II promoter; negative regulation of viral genome replication; organ morphogenesis; osteoclast differentiation; phagocytic cup; positive regulation of ERK1 and ERK2 cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of NF-kappaB import into nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of NFAT protein import into nucleus; positive regulation of apoptotic process; positive regulation of calcidiol 1-monooxygenase activity; positive regulation of chemokine (C-X-C motif) ligand 2 production; positive regulation of chemokine biosynthetic process; positive regulation of chronic inflammatory response to antigenic stimulus; positive regulation of cytokine secretion; positive regulation of fever generation; positive regulation of hair follicle development; positive regulation of heterotypic cell-cell adhesion; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of interferon-gamma production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 biosynthetic process; positive regulation of membrane protein ectodomain proteolysis; positive regulation of mitosis; positive regulation of mononuclear cell migration; positive regulation of neuron apoptotic process; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of podosome assembly; positive regulation of protein complex disassembly; positive regulation of protein kinase B signaling cascade; positive regulation of protein localization to cell surface; positive regulation of smooth muscle cell proliferation; positive regulation of synaptic transmission; positive regulation of transcription from RNA polymerase II promoter; positive regulation of translational initiation by iron; positive regulation of vitamin D biosynthetic process; protein import into nucleus, translocation; protein kinase B signaling cascade; receptor biosynthetic process; recycling endosome; regulation of branching involved in salivary gland morphogenesis; regulation of immunoglobulin secretion; regulation of insulin secretion; response to activity; response to drug; response to glucocorticoid stimulus; response to hypoxia; response to mechanical stimulus; response to salt stress; response to virus; sequestering of triglyceride; skeletal muscle contraction; transcription regulatory region DNA binding; transformed cell apoptotic process; tumor necrosis factor receptor binding; tumor necrosis factor-mediated signaling pathway",PF00229;,,,,,,,,,TNFA_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cortical actin cytoskeleton organization [GO:0030866]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; establishment of protein localization to plasma membrane [GO:0090002]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein import into nucleus, translocation [GO:0000060]; protein kinase B signaling [GO:0043491]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]" comp144741_c0_seq1,221,57.9186,0.54680923,50,19,,,,,,,,,3.00E-97,CHOYP_LOC100353582.2.2,,,,,,,,, comp144746_c0_seq1,472,44.4915,0.71228555,11,100,,1.00E-56,P42685,Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5),Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5),GO:0005524; GO:0030154; GO:0005737; GO:0008285; GO:0004715; GO:0005634; GO:0005886,ATP binding; cell differentiation; cytoplasm; negative regulation of cell proliferation; non-membrane spanning protein tyrosine kinase activity; nucleus; plasma membrane,PF07714;PF00017;PF00018;,3.00E-69,CHOYP_SRC1.1.1,,,,,,,FRK_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; innate immune response [GO:0045087]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp144760_c0_seq1,254,39.3701,1.06251647,0,61,,8.00E-18,O80501,Ras-related protein RABH1b (AtRABH1b) (Ras-related protein Rab6A) (AtRab6A),Ras-related protein RABH1b (AtRABH1b) (Ras-related protein Rab6A) (AtRab6A),GO:0005525; GO:0000139; GO:0005829; GO:0005768; GO:0005886; GO:0009506; GO:0015031; GO:0032940; GO:0007264; GO:0005802; GO:0005774; GO:0016192,GTP binding; Golgi membrane; cytosol; endosome; plasma membrane; plasmodesma; protein transport; secretion by cell; small GTPase mediated signal transduction; trans-Golgi network; vacuolar membrane; vesicle-mediated transport,PF00071;,,,,,,,,,RAH1B_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp144788_c0_seq1,914,41.2473,0.72883565,21,141,,2.00E-16,P57788,Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3),Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3),GO:0015629; GO:0016021; GO:0031965; GO:0005886; GO:0015355; GO:0015293,actin cytoskeleton; integral to membrane; nuclear membrane; plasma membrane; secondary active monocarboxylate transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT4_CHICK,Gallus gallus (Chicken), comp144810_c0_seq1,249,43.7751,0.69931198,7,53,,3.00E-17,Q54XH6,Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog (EC 1.-.-.-),Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog (EC 1.-.-.-),GO:0051213; GO:0046872,dioxygenase activity; metal ion binding,PF05721;,2.00E-24,CHOYP_PHYD1.2.2,,,,,,,PHYD1_DICDI,Dictyostelium discoideum (Slime mold), comp144817_c0_seq1,265,43.3962,0.24182163,7,36,,5.00E-17,Q8BL99,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,4.00E-20,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp144821_c0_seq1,325,56.9231,1.20630189,0,46,,1.00E-19,Q2YTD1,Alanine dehydrogenase 2 (EC 1.4.1.1),Alanine dehydrogenase 2 (EC 1.4.1.1),GO:0042853; GO:0000286,L-alanine catabolic process; alanine dehydrogenase activity,PF01262;PF05222;,,,,,,,,,DHA2_STAAB,Staphylococcus aureus (strain bovine RF122 / ET3-1),L-alanine catabolic process [GO:0042853] comp144822_c0_seq1,352,38.3523,1.24296778,53,9,,7.00E-06,Q923X4,"Glutaredoxin-2, mitochondrial","Glutaredoxin-2, mitochondrial",GO:0051537; GO:0045454; GO:0009055; GO:0046872; GO:0005739; GO:0005634; GO:0015035; GO:0042542; GO:0010033,"2 iron, 2 sulfur cluster binding; cell redox homeostasis; electron carrier activity; metal ion binding; mitochondrion; nucleus; protein disulfide oxidoreductase activity; response to hydrogen peroxide; response to organic substance",PF00462;,,,,,,,,,GLRX2_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033] comp144861_c0_seq1,465,43.0108,0.56280454,1,108,,2.00E-41,Q6ZMW2,Zinc finger protein 782,Zinc finger protein 782,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN782_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp144869_c0_seq1,568,40.669,0.56004111,12,62,,2.00E-56,Q9V5N8,Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),GO:0004930; GO:0007464; GO:0048057; GO:0016055; GO:0007411; GO:0005509; GO:0016339; GO:0050839; GO:0005911; GO:0048813; GO:0070593; GO:0007156; GO:0005887; GO:0016319; GO:0030178; GO:0007218; GO:0016318; GO:0030177; GO:0005057; GO:0050770; GO:0090175; GO:0051963; GO:0035159; GO:0007367; GO:0004888,"G-protein coupled receptor activity; R3/R4 cell fate commitment; R3/R4 development; Wnt receptor signaling pathway; axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell junction; dendrite morphogenesis; dendrite self-avoidance; homophilic cell adhesion; integral to plasma membrane; mushroom body development; negative regulation of Wnt receptor signaling pathway; neuropeptide signaling pathway; ommatidial rotation; positive regulation of Wnt receptor signaling pathway; receptor signaling protein activity; regulation of axonogenesis; regulation of establishment of planar polarity; regulation of synapse assembly; regulation of tube length, open tracheal system; segment polarity determination; transmembrane signaling receptor activity",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,STAN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]" comp144883_c0_seq1,907,44.6527,0.49001679,17,45,,1.00E-17,O77086,Guanine nucleotide-releasing factor 2 (CRK SH3-binding GNRP) (DC3G),Guanine nucleotide-releasing factor 2 (CRK SH3-binding GNRP) (DC3G),GO:0005088; GO:0007265; GO:0005622; GO:0016203; GO:0032317; GO:0045214; GO:0007525,Ras guanyl-nucleotide exchange factor activity; Ras protein signal transduction; intracellular; muscle attachment; regulation of Rap GTPase activity; sarcomere organization; somatic muscle development,PF00617;PF00618;,6.00E-19,CHOYP_LOC662211.1.1,,,,,,,C3G_DROME,Drosophila melanogaster (Fruit fly),muscle attachment [GO:0016203]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; regulation of GTPase activity [GO:0043087]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525] comp144884_c0_seq1,510,38.6275,1.10629291,8,82,,1.00E-34,Q9I8C7,Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10),Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10),GO:0004889; GO:0005262; GO:0030054; GO:0016021; GO:0045211,acetylcholine-activated cation-selective channel activity; calcium channel activity; cell junction; integral to membrane; postsynaptic membrane,PF02931;PF02932;,1.00E-43,CHOYP_SMP_037960.1.1,,,,,,,ACH10_CHICK,Gallus gallus (Chicken),"signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" comp144886_c0_seq1,285,45.614,0.88757359,9,37,,5.00E-13,A2BFP5,Solute carrier family 12 member 9,Solute carrier family 12 member 9,GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF00324;PF03522;,,,,,,,,,S12A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144897_c0_seq1,615,37.7236,0.66713258,15,60,,1.00E-59,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,5.00E-18,CHOYP_MAN2A1.1.1,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp144905_c0_seq1,262,38.5496,0.31636387,0,50,,,,,,,,,1.00E-14,CHOYP_EF1A.4.4,,,,,,,,, comp144913_c0_seq1,505,42.1782,0.17959254,36,34,,3.00E-61,Q96AG4,Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34),Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34),GO:0005783; GO:0005789; GO:0016021; GO:0042645; GO:0005635,endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; mitochondrial nucleoid; nuclear envelope,PF13855;,4.00E-43,CHOYP_LOC100669963.1.1,5.00E-65,ruditapes2_lrc5740,,,,,LRC59_HUMAN,Homo sapiens (Human), comp144916_c0_seq1,561,43.1373,0.5758215,16,32,,1.00E-55,Q6ZRF8,RING finger protein 207,RING finger protein 207,GO:0005622; GO:0008270,intracellular; zinc ion binding,PF00643;PF00097;,9.00E-33,CHOYP_BRAFLDRAFT_117193.1.2,,,,,,,RN207_HUMAN,Homo sapiens (Human),cell-cell signaling involved in cardiac conduction [GO:0086019]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of gene expression [GO:0010628]; positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [GO:1903954]; positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903762]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart looping [GO:1901207] comp144926_c0_seq1,264,32.5758,0.46007605,3,47,,1.00E-06,P53968,Transcriptional regulator CRZ1,Transcriptional regulator CRZ1,GO:0001077; GO:0006038; GO:0071483; GO:0000987; GO:0005737; GO:0046872; GO:0005634; GO:2001040; GO:0061423; GO:1900622; GO:0007329; GO:0061422; GO:0061400; GO:0061404; GO:0097301,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell wall chitin biosynthetic process; cellular response to blue light; core promoter proximal region sequence-specific DNA binding; cytoplasm; metal ion binding; nucleus; positive regulation of cellular response to drug; positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling; positive regulation of transcription from RNA polymerase II promoter by pheromones; positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion; positive regulation of transcription from RNA polymerase II promoter in response to increased salt; regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter,PF00096;,,,,,,,,,CRZ1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to blue light [GO:0071483]; cell wall chitin biosynthetic process [GO:0006038]; ion homeostasis [GO:0050801]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter [GO:0061423]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling [GO:1900622]; positive regulation of transcription from RNA polymerase II promoter by pheromones [GO:0007329]; positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [GO:0061422]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400]; positive regulation of transcription from RNA polymerase II promoter in response to increased salt [GO:0061404]; regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter [GO:0097301] comp144927_c0_seq1,636,46.3836,0.67622248,24,51,,4.00E-86,O46382,Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1),Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1),GO:0005086; GO:0000139; GO:0007030; GO:0005829; GO:0010256; GO:0034259; GO:0030837; GO:0016363; GO:0005730; GO:0048471; GO:0090284; GO:0090303; GO:0034237; GO:0015031; GO:0032012; GO:2000114; GO:0030532; GO:0005802,ARF guanyl-nucleotide exchange factor activity; Golgi membrane; Golgi organization; cytosol; endomembrane system organization; negative regulation of Rho GTPase activity; negative regulation of actin filament polymerization; nuclear matrix; nucleolus; perinuclear region of cytoplasm; positive regulation of protein glycosylation in Golgi; positive regulation of wound healing; protein kinase A regulatory subunit binding; protein transport; regulation of ARF protein signal transduction; regulation of establishment of cell polarity; small nuclear ribonucleoprotein complex; trans-Golgi network,PF16213;PF09324;PF01369;PF12783;,1.00E-89,CHOYP_BIG1.2.3,,,,,,,BIG1_BOVIN,Bos taurus (Bovine),endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]; vesicle-mediated transport [GO:0016192] comp144956_c0_seq1,376,42.2872,0.24205629,7,48,,3.00E-34,O54956,DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B),DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B),GO:0003677; GO:0006261; GO:0003887; GO:0008622,DNA binding; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; epsilon DNA polymerase complex,PF04042;PF12213;,,,,,,,,,DPOE2_MOUSE,Mus musculus (Mouse),DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] comp144957_c0_seq1,265,44.1509,1.49068125,2,33,,,,,,,,,4.00E-20,CHOYP_LOC100377534.1.1,,,,,,,,, comp144961_c0_seq1,451,31.2639,0.45473061,7,43,,,,,,,,,2.00E-28,CHOYP_LOC100636931.6.8,,,,,,,,, comp144974_c0_seq1,734,39.5095,0.0707787,16,58,,5.00E-85,Q5U3G6,Protein YIF1B (YIP1-interacting factor homolog B),Protein YIF1B (YIP1-interacting factor homolog B),GO:0016021,integral to membrane,,2.00E-68,CHOYP_LOC100176210.1.1,,,,,,,YIF1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp144975_c0_seq1,575,43.1304,0.56426503,5,79,,4.00E-13,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp144991_c0_seq1,206,44.6602,0.88212306,11,31,,3.00E-13,O55071,Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19),Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2BJ_MOUSE,Mus musculus (Mouse),epoxygenase P450 pathway [GO:0019373] comp145004_c0_seq1,262,41.9847,0.54339635,3,32,,,,,,,,,2.00E-31,CHOYP_LOC753295.1.1,2.00E-41,ruditapes_c13121,,,,,,, comp145006_c0_seq1,234,47.8632,0.52877854,1,30,,3.00E-12,P80109,Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),GO:0006507; GO:0002042; GO:0071277; GO:0071397; GO:0035690; GO:0071467; GO:0071401; GO:0002062; GO:0002430; GO:0005737; GO:0005615; GO:0004621; GO:0034364; GO:0008286; GO:0043231; GO:0008285; GO:0010897; GO:0001503; GO:0046470; GO:0010694; GO:0043065; GO:0045919; GO:0010595; GO:0010907; GO:0010983; GO:0035774; GO:0051044; GO:0010867; GO:0005578; GO:1900076; GO:0009749; GO:0017080; GO:0070633,GPI anchor release; cell migration involved in sprouting angiogenesis; cellular response to calcium ion; cellular response to cholesterol; cellular response to drug; cellular response to pH; cellular response to triglyceride; chondrocyte differentiation; complement receptor mediated signaling pathway; cytoplasm; extracellular space; glycosylphosphatidylinositol phospholipase D activity; high-density lipoprotein particle; insulin receptor signaling pathway; intracellular membrane-bounded organelle; negative regulation of cell proliferation; negative regulation of triglyceride catabolic process; ossification; phosphatidylcholine metabolic process; positive regulation of alkaline phosphatase activity; positive regulation of apoptotic process; positive regulation of cytolysis; positive regulation of endothelial cell migration; positive regulation of glucose metabolic process; positive regulation of high-density lipoprotein particle clearance; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of membrane protein ectodomain proteolysis; positive regulation of triglyceride biosynthetic process; proteinaceous extracellular matrix; regulation of cellular response to insulin stimulus; response to glucose stimulus; sodium channel regulator activity; transepithelial transport,PF01839;PF00882;,,,,,,,,,PHLD_BOVIN,Bos taurus (Bovine),cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633] comp145007_c0_seq1,531,43.1262,0.63093203,11,47,,4.00E-80,P49282,Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2),Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2),GO:0005903; GO:0009986; GO:0015087; GO:0048813; GO:0005769; GO:0012505; GO:0010008; GO:0048821; GO:0070627; GO:0015093; GO:0006783; GO:0015078; GO:0016021; GO:0005887; GO:0006811; GO:0055072; GO:0007611; GO:0060586; GO:0055037; GO:0005215,brush border; cell surface; cobalt ion transmembrane transporter activity; dendrite morphogenesis; early endosome; endomembrane system; endosome membrane; erythrocyte development; ferrous iron import; ferrous iron transmembrane transporter activity; heme biosynthetic process; hydrogen ion transmembrane transporter activity; integral to membrane; integral to plasma membrane; ion transport; iron ion homeostasis; learning or memory; multicellular organismal iron ion homeostasis; recycling endosome; transporter activity,PF01566;,2.00E-71,CHOYP_LOC100304514.1.1,,,,,,,NRAM2_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cadmium ion transmembrane transport [GO:0070574]; cellular response to oxidative stress [GO:0034599]; cobalt ion transport [GO:0006824]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detection of oxygen [GO:0003032]; erythrocyte development [GO:0048821]; ferrous iron import [GO:0070627]; ferrous iron transport [GO:0015684]; heme biosynthetic process [GO:0006783]; iron ion transport [GO:0006826]; lead ion transport [GO:0015692]; learning or memory [GO:0007611]; manganese ion transport [GO:0006828]; multicellular organismal iron ion homeostasis [GO:0060586]; nickel cation transport [GO:0015675]; porphyrin-containing compound biosynthetic process [GO:0006779]; porphyrin-containing compound metabolic process [GO:0006778]; proton transport [GO:0015992]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; vanadium ion transport [GO:0015676] comp145010_c0_seq1,608,45.8882,0.44596836,36,18,,2.00E-32,Q8BGG7,Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2),Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2),GO:0005737; GO:0090331; GO:0006469; GO:0005634; GO:0035335; GO:0004725; GO:0051279,cytoplasm; negative regulation of platelet aggregation; negative regulation of protein kinase activity; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; regulation of release of sequestered calcium ion into cytosol,PF00300;PF14604;PF00627;,2.00E-17,CHOYP_UBS3B.1.1,,,,,,,UBS3B_MOUSE,Mus musculus (Mouse),negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of signal transduction [GO:0009968]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of osteoclast differentiation [GO:0045670]; regulation of release of sequestered calcium ion into cytosol [GO:0051279] comp145018_c0_seq1,328,46.3415,0.40891715,12,32,,2.00E-19,P48553,Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),GO:0005794; GO:0016021; GO:0015081; GO:0016192,Golgi apparatus; integral to membrane; sodium ion transmembrane transporter activity; vesicle-mediated transport,PF12584;,,,,,,,,,TPC10_HUMAN,Homo sapiens (Human),COPII vesicle coating [GO:0048208]; early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; sodium ion transport [GO:0006814] comp145038_c0_seq1,418,40.4306,0.52963786,28,19,,1.00E-08,O01346,"Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)","Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)",GO:0007411; GO:0019187; GO:0007298; GO:0045165; GO:0033227; GO:0006688; GO:0016021; GO:0042248; GO:0008049; GO:0045434; GO:0030720; GO:0016325; GO:0001744; GO:0007299; GO:0046662,"axon guidance; beta-1,4-mannosyltransferase activity; border follicle cell migration; cell fate commitment; dsRNA transport; glycosphingolipid biosynthetic process; integral to membrane; maintenance of polarity of follicular epithelium; male courtship behavior; negative regulation of female receptivity, post-mating; oocyte localization involved in germarium-derived egg chamber formation; oocyte microtubule cytoskeleton organization; optic lobe placode formation; ovarian follicle cell-cell adhesion; regulation of oviposition",PF13632;,,,,,,,,,EGH_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell fate commitment [GO:0045165]; dsRNA transport [GO:0033227]; germarium-derived egg chamber formation [GO:0007293]; germ cell development [GO:0007281]; glycosphingolipid biosynthetic process [GO:0006688]; maintenance of polarity of follicular epithelium [GO:0042248]; male courtship behavior [GO:0008049]; morphogenesis of follicular epithelium [GO:0016333]; negative regulation of female receptivity, post-mating [GO:0045434]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; optic lobe placode formation [GO:0001744]; ovarian follicle cell-cell adhesion [GO:0007299]; ovarian follicle cell development [GO:0030707]; peripheral nervous system neuron development [GO:0048935]; regulation of oviposition [GO:0046662]" comp145063_c0_seq1,278,41.3669,0.60728398,0,26,,2.00E-40,Q29P71,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,2.00E-51,CHOYP_MYO7A.1.3,,,,,,,MYO7A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp145065_c0_seq1,286,40.9091,0.67332201,6,22,,6.00E-16,Q9WUH1,Transmembrane protein 115 (Protein PL6 homolog),Transmembrane protein 115 (Protein PL6 homolog),GO:0005794; GO:0016021; GO:0005634,Golgi apparatus; integral to membrane; nucleus,PF08551;,,,,,,,,,TM115_MOUSE,Mus musculus (Mouse),"protein glycosylation [GO:0006486]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp145071_c0_seq1,292,43.1507,0.2228728,2,38,,9.00E-08,Q5JTZ9,"Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)","Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)",GO:0005524; GO:0004813; GO:0046872; GO:0070143; GO:0033108; GO:0005739; GO:0000049,ATP binding; alanine-tRNA ligase activity; metal ion binding; mitochondrial alanyl-tRNA aminoacylation; mitochondrial respiratory chain complex assembly; mitochondrion; tRNA binding,PF01411;PF07973;,,,,,,,,,SYAM_HUMAN,Homo sapiens (Human),mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; mitochondrial respiratory chain complex assembly [GO:0033108]; tRNA modification [GO:0006400] comp145072_c0_seq1,499,45.2906,0.45481039,19,53,,4.00E-17,Q16851,UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),GO:0006011; GO:0006065; GO:0003983; GO:0052695; GO:0005829; GO:0006006; GO:0005978; GO:0046872; GO:0016310; GO:0006805,UDP-glucose metabolic process; UDP-glucuronate biosynthetic process; UTP:glucose-1-phosphate uridylyltransferase activity; cellular glucuronidation; cytosol; glucose metabolic process; glycogen biosynthetic process; metal ion binding; phosphorylation; xenobiotic metabolic process,PF01704;,,,1.00E-73,ruditapes_c21281,,,,,UGPA_HUMAN,Homo sapiens (Human),glucose 1-phosphate metabolic process [GO:0019255]; glycogen biosynthetic process [GO:0005978]; UDP-glucose metabolic process [GO:0006011]; UDP-glucuronate biosynthetic process [GO:0006065] comp145077_c0_seq1,348,42.2414,1.1023874,9,44,,2.00E-09,O02713,Solute carrier family 22 member 2 (Apical organic cation transporter) (Organic cation transporter 2),Solute carrier family 22 member 2 (Apical organic cation transporter) (Organic cation transporter 2),GO:0016021; GO:0015075,integral to membrane; ion transmembrane transporter activity,PF00083;,,,,,,,,,S22A2_PIG,Sus scrofa (Pig),choline transport [GO:0015871]; dopamine transport [GO:0015872] comp145081_c0_seq1,352,46.0227,1.12986737,0,51,,9.00E-17,Q5M9A7,Post-GPI attachment to proteins factor 2,Post-GPI attachment to proteins factor 2,GO:0006506; GO:0000139; GO:0005789; GO:0016021; GO:0008565,GPI anchor biosynthetic process; Golgi membrane; endoplasmic reticulum membrane; integral to membrane; protein transporter activity,PF10277;,,,,,,,,,PGAP2_XENLA,Xenopus laevis (African clawed frog),GPI anchor biosynthetic process [GO:0006506] comp145083_c0_seq1,383,43.342,0.86839127,8,29,,3.00E-18,Q16635,Tafazzin (Protein G4.5),Tafazzin (Protein G4.5),GO:0047184; GO:0060048; GO:0048738; GO:0035965; GO:0032049; GO:0042407; GO:0030097; GO:0016021; GO:0042775; GO:0005743; GO:0032981; GO:0005886; GO:0007519; GO:0044281,1-acylglycerophosphocholine O-acyltransferase activity; cardiac muscle contraction; cardiac muscle tissue development; cardiolipin acyl-chain remodeling; cardiolipin biosynthetic process; cristae formation; hemopoiesis; integral to membrane; mitochondrial ATP synthesis coupled electron transport; mitochondrial inner membrane; mitochondrial respiratory chain complex I assembly; plasma membrane; skeletal muscle tissue development; small molecule metabolic process,PF01553;,,,,,,,,,TAZ_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; cristae formation [GO:0042407]; heart development [GO:0007507]; hemopoiesis [GO:0030097]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial respiratory chain complex I assembly [GO:0032981]; muscle contraction [GO:0006936]; skeletal muscle tissue development [GO:0007519] comp145084_c0_seq1,549,40.8015,0.7894763,3,76,,9.00E-15,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,,,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp145086_c0_seq1,362,43.3702,0.91054207,0,45,,3.00E-14,P16273,Pathogen-related protein,Pathogen-related protein,GO:0006952; GO:0009607,defense response; response to biotic stimulus,,6.00E-14,CHOYP_TRIADDRAFT_29994.1.1,,,,,,,PRPX_HORVU,Hordeum vulgare (Barley),defense response [GO:0006952]; response to biotic stimulus [GO:0009607] comp145089_c0_seq1,475,41.2632,0.67532767,3,79,,1.00E-37,P91253,Probable glutathione S-transferase 7 (EC 2.5.1.18) (GST class-sigma),Probable glutathione S-transferase 7 (EC 2.5.1.18) (GST class-sigma),GO:0004364,glutathione transferase activity,PF14497;PF02798;,,,2.00E-58,ruditapes2_lrc4459,,,,,GST7_CAEEL,Caenorhabditis elegans,innate immune response [GO:0045087] comp145095_c0_seq1,433,35.3349,0.74417407,55,10,,6.00E-29,O79552,Cytochrome c oxidase subunit 3 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide III),Cytochrome c oxidase subunit 3 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide III),GO:0019646; GO:0004129; GO:0016021; GO:0005743; GO:0045277,aerobic electron transport chain; cytochrome-c oxidase activity; integral to membrane; mitochondrial inner membrane; respiratory chain complex IV,PF00510;,3.00E-37,CHOYP_COX2.2.2,,,,,,,COX3_DINSE,Lycodon semicarinatus (Ryukyu odd-tooth snake) (Eumesodon semicarinatus),aerobic electron transport chain [GO:0019646] comp145096_c0_seq1,272,45.2206,0.58615929,5,27,,4.00E-24,A7MB11,Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1),Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1),GO:0005737; GO:0006886; GO:0005083; GO:0016192,cytoplasm; intracellular protein transport; small GTPase regulator activity; vesicle-mediated transport,PF00637;PF00780;PF10366;PF10367;,,,,,,,,,TGFA1_BOVIN,Bos taurus (Bovine),intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] comp145110_c0_seq1,205,46.3415,0.27418576,4,31,,3.00E-14,Q75N73,Zinc transporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14),Zinc transporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14),GO:0015093; GO:0016021; GO:0005886; GO:0005385,ferrous iron transmembrane transporter activity; integral to membrane; plasma membrane; zinc ion transmembrane transporter activity,PF02535;,,,,,,,,,S39AE_MOUSE,Mus musculus (Mouse),cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc II ion transmembrane import [GO:0071578]; zinc II ion transmembrane transport [GO:0071577]; zinc II ion transport [GO:0006829] comp145124_c0_seq1,214,40.1869,0.35834116,1,31,,4.00E-06,P03361,Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)],Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0075713; GO:0090305; GO:0004523; GO:0046718,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; viral entry into host cell,PF00552;PF00075;PF00665;PF00078;,9.00E-15,CHOYP_LOC100708199.3.6,,,,,,,POL_BLVJ,Bovine leukemia virus (isolate Japanese BLV-1) (BLV),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp145142_c0_seq1,256,39.8438,0.59308597,2,27,,2.00E-12,Q9UC06,Zinc finger protein 70 (Zinc finger protein N27C7-1),Zinc finger protein 70 (Zinc finger protein N27C7-1),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZNF70_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp145144_c0_seq1,217,38.2488,0.64043663,3,24,,9.00E-13,P18502,Protein patched (Hedgehog receptor),Protein patched (Hedgehog receptor),GO:0001746; GO:0048099; GO:0007411; GO:0016311; GO:0035225; GO:0009880; GO:0030139; GO:0007455; GO:0042078; GO:0008406; GO:0008158; GO:0007476; GO:0005887; GO:0055088; GO:0030228; GO:0045879; GO:0030707; GO:0048471; GO:0007422; GO:0006508; GO:0007346; GO:0042306; GO:0007367; GO:0007224; GO:0048103; GO:0048100,"Bolwig's organ morphogenesis; anterior/posterior lineage restriction, imaginal disc; axon guidance; dephosphorylation; determination of genital disc primordium; embryonic pattern specification; endocytic vesicle; eye-antennal disc morphogenesis; germ-line stem cell division; gonad development; hedgehog receptor activity; imaginal disc-derived wing morphogenesis; integral to plasma membrane; lipid homeostasis; lipoprotein particle receptor activity; negative regulation of smoothened signaling pathway; ovarian follicle cell development; perinuclear region of cytoplasm; peripheral nervous system development; proteolysis; regulation of mitotic cell cycle; regulation of protein import into nucleus; segment polarity determination; smoothened signaling pathway; somatic stem cell division; wing disc anterior/posterior pattern formation",PF02460;,,,,,,,,,PTC_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior lineage restriction, imaginal disc [GO:0048099]; anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; blastoderm segmentation [GO:0007350]; Bolwig's organ morphogenesis [GO:0001746]; dephosphorylation [GO:0016311]; determination of genital disc primordium [GO:0035225]; embryonic pattern specification [GO:0009880]; eye-antennal disc morphogenesis [GO:0007455]; germ-line stem cell division [GO:0042078]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; lipid homeostasis [GO:0055088]; negative regulation of smoothened signaling pathway [GO:0045879]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein import into nucleus [GO:0042306]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; somatic stem cell division [GO:0048103]; wing disc anterior/posterior pattern formation [GO:0048100]" comp145152_c0_seq1,403,38.9578,1.11675484,4,38,,4.00E-21,Q8CHL0,Frizzled-5 (Fz-5),Frizzled-5 (Fz-5),GO:0004930; GO:0000139; GO:0030165; GO:0033077; GO:0042813; GO:0001525; GO:0006915; GO:0007409; GO:0007420; GO:0060070; GO:0042995; GO:0005737; GO:0031076; GO:0008406; GO:0016021; GO:0060716; GO:0005886; GO:0031077,G-protein coupled receptor activity; Golgi membrane; PDZ domain binding; T cell differentiation in thymus; Wnt-activated receptor activity; angiogenesis; apoptotic process; axonogenesis; brain development; canonical Wnt receptor signaling pathway; cell projection; cytoplasm; embryonic camera-type eye development; gonad development; integral to membrane; labyrinthine layer blood vessel development; plasma membrane; post-embryonic camera-type eye development,PF01534;PF01392;,,,,,,,,,FZD5_RAT,Rattus norvegicus (Rat),canonical Wnt signaling pathway [GO:0060070]; multicellular organism development [GO:0007275]; non-canonical Wnt signaling pathway [GO:0035567] comp145153_c0_seq1,772,40.8031,0.95802854,26,66,,3.00E-20,Q8AWD1,Mid1-interacting protein 1-like (Gastrulation-specific protein G12-like),Mid1-interacting protein 1-like (Gastrulation-specific protein G12-like),GO:0005737; GO:0005874; GO:0005634,cytoplasm; microtubule; nucleus,PF07084;,,,,,,,,,M1I1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp145171_c0_seq1,565,35.7522,0.68083613,13,39,,3.00E-11,Q08DS0,Kelch-like protein 21,Kelch-like protein 21,GO:0031463; GO:0051301; GO:0035853; GO:0005737; GO:0007067; GO:0005827; GO:0016567; GO:0032465,Cul3-RING ubiquitin ligase complex; cell division; chromosome passenger complex localization to spindle midzone; cytoplasm; mitosis; polar microtubule; protein ubiquitination; regulation of cytokinesis,PF07707;PF00651;PF01344;,,,,,,,,,KLH21_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; chromosome passenger complex localization to spindle midzone [GO:0035853]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cytokinesis [GO:0032465] comp145174_c0_seq1,244,58.6066,0.91097421,0,29,,2.00E-24,O06391,Uncharacterized protein Rv0525,Uncharacterized protein Rv0525,GO:0040007; GO:0005886,growth; plasma membrane,PF00300;,,,,,,,,,Y525_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),growth [GO:0040007] comp145177_c0_seq1,607,41.5157,1.13374793,2,69,,,,,,,,,,,5.00E-28,ruditapes_lrc36305,,,,,,, comp145182_c0_seq1,283,41.6961,0.49306171,5,32,,6.00E-07,Q86T29,Zinc finger protein 605,Zinc finger protein 605,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN605_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp145184_c0_seq1,458,43.0131,0.52073268,21,34,,9.00E-54,O75197,Low-density lipoprotein receptor-related protein 5 (LRP-5),Low-density lipoprotein receptor-related protein 5 (LRP-5),GO:0044332; GO:0042813; GO:0017147; GO:0060612; GO:0009952; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042632; GO:0015026; GO:0048596; GO:0030326; GO:0060059; GO:0006897; GO:0005783; GO:0001702; GO:0006007; GO:0016021; GO:0045668; GO:0071901; GO:0002076; GO:0005886; GO:0045600; GO:0002053; GO:0045840; GO:0045944; GO:0043235; GO:0008217; GO:0060828; GO:0061178; GO:0061304,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; Wnt-protein binding; adipose tissue development; anterior/posterior pattern specification; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cholesterol homeostasis; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic limb morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; gastrulation with mouth forming second; glucose catabolic process; integral to membrane; negative regulation of osteoblast differentiation; negative regulation of protein serine/threonine kinase activity; osteoblast development; plasma membrane; positive regulation of fat cell differentiation; positive regulation of mesenchymal cell proliferation; positive regulation of mitosis; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of blood pressure; regulation of canonical Wnt receptor signaling pathway; regulation of insulin secretion involved in cellular response to glucose stimulus; retinal blood vessel morphogenesis,PF00057;PF00058;,9.00E-13,CHOYP_LRP6.3.6,,,,,,,LRP5_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp145193_c0_seq1,209,50.7177,1.08529616,0,37,,2.00E-11,Q3BAI2,Uncharacterized protein ORF91,Uncharacterized protein ORF91,GO:0009507,chloroplast,,1.00E-19,CHOYP_contig_009415,,,,,,,YCX91_PHAAO,Phalaenopsis aphrodite subsp. formosana (Moth orchid), comp145195_c0_seq1,538,44.2379,1.03125356,1,79,,2.00E-27,Q2NL00,Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1),GO:0005737; GO:0004364,cytoplasm; glutathione transferase activity,PF00043;PF02798;,,,,,,,,,GSTT1_BOVIN,Bos taurus (Bovine),glutathione metabolic process [GO:0006749] comp145227_c0_seq1,357,46.4986,0.52454624,6,21,,6.00E-10,Q9Z0J1,Reversion-inducing cysteine-rich protein with Kazal motifs (mRECK),Reversion-inducing cysteine-rich protein with Kazal motifs (mRECK),GO:0031225; GO:0001955; GO:0007566; GO:0004866; GO:0030198; GO:0005886; GO:0004867,anchored to membrane; blood vessel maturation; embryo implantation; endopeptidase inhibitor activity; extracellular matrix organization; plasma membrane; serine-type endopeptidase inhibitor activity,PF07648;,,,,,,,,,RECK_MOUSE,Mus musculus (Mouse),blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684]; positive regulation of Notch signaling pathway [GO:0045747] comp145228_c0_seq1,295,47.7966,0.53731961,6,25,,2.00E-28,Q1PRL4,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:0021915; GO:2000637; GO:0051865; GO:0060964; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; neural tube development; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of gene silencing by miRNA; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,4.00E-21,CHOYP_LOC100367035.1.1,,,,,,,LIN41_CHICK,Gallus gallus (Chicken),fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] comp145234_c0_seq1,389,46.7866,0.53252586,7,28,,7.00E-27,Q5EBM0,"UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6)","UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6)",GO:0005524; GO:0033862; GO:0071222; GO:0004127; GO:0006233; GO:0006227; GO:0005739; GO:0004550; GO:0009142; GO:0005634; GO:0004798,ATP binding; UMP kinase activity; cellular response to lipopolysaccharide; cytidylate kinase activity; dTDP biosynthetic process; dUDP biosynthetic process; mitochondrion; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; nucleus; thymidylate kinase activity,,1.00E-15,CHOYP_LOC100493600.1.1,,,,,,,CMPK2_HUMAN,Homo sapiens (Human),cellular response to lipopolysaccharide [GO:0071222]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp145255_c0_seq1,623,35.313,0.36126137,3,72,,4.00E-28,P17035,Zinc finger protein 28 (Zinc finger protein KOX24),Zinc finger protein 28 (Zinc finger protein KOX24),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZNF28_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp145262_c0_seq1,488,41.3934,0.55112936,10,34,,1.00E-07,Q32PH0,Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein),Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein),GO:0005794; GO:0030154; GO:0005783,Golgi apparatus; cell differentiation; endoplasmic reticulum,PF08626;,,,,,,,,,TPPC9_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154] comp145267_c0_seq1,461,40.9978,0.27017671,6,53,,6.00E-34,O95847,Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27),Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27),GO:0045177; GO:0035356; GO:0006091; GO:0048839; GO:0016021; GO:0005743; GO:0043066; GO:0070997; GO:0043025; GO:0008284; GO:0051562; GO:0006810,apical part of cell; cellular triglyceride homeostasis; generation of precursor metabolites and energy; inner ear development; integral to membrane; mitochondrial inner membrane; negative regulation of apoptotic process; neuron death; neuronal cell body; positive regulation of cell proliferation; reduction of mitochondrial calcium ion concentration; transport,PF00153;,,,,,,,,,UCP4_HUMAN,Homo sapiens (Human),generation of precursor metabolites and energy [GO:0006091]; proton transport [GO:0015992]; translation [GO:0006412] comp145273_c0_seq1,702,37.8917,0.39798541,21,27,,6.00E-29,Q6J1I7,RING finger protein 166,RING finger protein 166,GO:0008270,zinc ion binding,PF05605;,,,,,,,,,RN166_RAT,Rattus norvegicus (Rat),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209] comp145274_c0_seq1,794,43.5768,0.34999548,10,74,,2.00E-36,A0JMU5,Putative protein arginine N-methyltransferase 10 (EC 2.1.1.-),Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-),GO:0005737; GO:0008276,cytoplasm; protein methyltransferase activity,,,,,,,,,,ANM10_XENLA,Xenopus laevis (African clawed frog),protein methylation [GO:0006479] comp145277_c0_seq1,397,40.3023,1.12218757,3,49,,,,,,,,,,,2.00E-19,ruditapes_c7404,,,,,,, comp145281_c0_seq1,448,47.9911,0.62328959,22,26,,3.00E-45,A6QQM4,Zinc finger protein 474,Zinc finger protein 474,GO:0046872,metal ion binding,,1.00E-61,CHOYP_LOC100368109.1.1,,,,,,,ZN474_BOVIN,Bos taurus (Bovine), comp145283_c0_seq1,256,53.9062,1.18858236,0,35,,1.00E-08,Q07051,Elongation factor 1-alpha (EF-1-alpha) (Fragment),Elongation factor 1-alpha (EF-1-alpha) (Fragment),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,,,,,,,,,EF1A_EIMBO,Eimeria bovis, comp145285_c0_seq1,694,41.0663,0.48130294,14,59,,4.00E-28,Q5R800,Transmembrane protein 59,Transmembrane protein 59,GO:0000139; GO:0006914; GO:0016021; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0005886; GO:0010508,Golgi membrane; autophagy; integral to membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; plasma membrane; positive regulation of autophagy,PF12280;,,,,,,,,,TMM59_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),autophagy [GO:0006914]; positive regulation of autophagy [GO:0010508] comp14529_c0_seq1,259,32.4324,0.44445107,4,0,,4.00E-18,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp145300_c0_seq1,284,42.6056,0.78125969,14,28,,1.00E-15,Q8C0I1,"Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)","Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)",GO:0071949; GO:0008762; GO:0008609; GO:0008611; GO:0005739; GO:0005778,FAD binding; UDP-N-acetylmuramate dehydrogenase activity; alkylglycerone-phosphate synthase activity; ether lipid biosynthetic process; mitochondrion; peroxisomal membrane,PF02913;PF01565;,9.00E-17,CHOYP_AGPS.1.1,,,,,,,ADAS_MOUSE,Mus musculus (Mouse),ether lipid biosynthetic process [GO:0008611]; lipid biosynthetic process [GO:0008610] comp145305_c0_seq1,780,49.359,0.34532749,58,15,,3.00E-75,A6QQM4,Zinc finger protein 474,Zinc finger protein 474,GO:0046872,metal ion binding,,2.00E-48,CHOYP_LOC100368109.1.1,,,,,,,ZN474_BOVIN,Bos taurus (Bovine), comp145315_c0_seq1,259,44.0154,0.7312609,0,24,,,,,,,,,,,3.00E-20,ruditapes2_c3329,,,,,,, comp145316_c0_seq1,235,48.9362,1.55071644,0,30,,2.00E-11,Q9SQ80,Gibberellin 2-beta-dioxygenase 1 (EC 1.14.11.13) (GA 2-oxidase 1) (Gibberellin 2-beta-hydroxylase 1) (Gibberellin 2-oxidase 1) (Protein SLENDER),Gibberellin 2-beta-dioxygenase 1 (EC 1.14.11.13) (GA 2-oxidase 1) (Gibberellin 2-beta-hydroxylase 1) (Gibberellin 2-oxidase 1) (Protein SLENDER),GO:0045543; GO:0009686; GO:0005506,gibberellin 2-beta-dioxygenase activity; gibberellin biosynthetic process; iron ion binding,PF03171;PF14226;,,,1.00E-11,ruditapes_c27218,,,,,G2OX1_PEA,Pisum sativum (Garden pea),gibberellin biosynthetic process [GO:0009686] comp145321_c0_seq1,417,46.5228,0.66816241,4,31,,6.00E-49,Q5JWR5,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,3.00E-18,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp145330_c0_seq1,205,40.4878,0.12622849,1,19,,2.00E-10,Q9JJI6,GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O),GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O),GO:0006506; GO:0005789; GO:0016021; GO:0016780,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; phosphotransferase activity, for other substituted phosphate groups",PF01663;,,,,,,,,,PIGO_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp145337_c0_seq1,255,42.7451,0.43716519,0,27,,2.00E-21,P22303,Acetylcholinesterase (AChE) (EC 3.1.1.7),Acetylcholinesterase (AChE) (EC 3.1.1.7),GO:0006260; GO:0005794; GO:0042166; GO:0001507; GO:0003990; GO:0042982; GO:0031225; GO:0030424; GO:0005605; GO:0001540; GO:0004091; GO:0007155; GO:0030054; GO:0008283; GO:0009986; GO:0019695; GO:0005518; GO:0030425; GO:0005788; GO:0005615; GO:0043236; GO:0007517; GO:0032223; GO:0031594; GO:0042136; GO:0045212; GO:0005634; GO:0002076; GO:0048471; GO:0006656; GO:0050714; GO:0045211; GO:0042734; GO:0042803; GO:0051262; GO:0031623; GO:0050770; GO:0048814; GO:0001919; GO:0009611; GO:0060041; GO:0017171; GO:0007416,"DNA replication; Golgi apparatus; acetylcholine binding; acetylcholine catabolic process in synaptic cleft; acetylcholinesterase activity; amyloid precursor protein metabolic process; anchored to membrane; axon; basal lamina; beta-amyloid binding; carboxylesterase activity; cell adhesion; cell junction; cell proliferation; cell surface; choline metabolic process; collagen binding; dendrite; endoplasmic reticulum lumen; extracellular space; laminin binding; muscle organ development; negative regulation of synaptic transmission, cholinergic; neuromuscular junction; neurotransmitter biosynthetic process; neurotransmitter receptor biosynthetic process; nucleus; osteoblast development; perinuclear region of cytoplasm; phosphatidylcholine biosynthetic process; positive regulation of protein secretion; postsynaptic membrane; presynaptic membrane; protein homodimerization activity; protein tetramerization; receptor internalization; regulation of axonogenesis; regulation of dendrite morphogenesis; regulation of receptor recycling; response to wounding; retina development in camera-type eye; serine hydrolase activity; synapse assembly",PF08674;PF00135;,,,,,,,,,ACES_HUMAN,Homo sapiens (Human),"acetylcholine catabolic process [GO:0006581]; acetylcholine catabolic process in synaptic cleft [GO:0001507]; amyloid precursor protein metabolic process [GO:0042982]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; DNA replication [GO:0006260]; muscle organ development [GO:0007517]; negative regulation of synaptic transmission, cholinergic [GO:0032223]; nervous system development [GO:0007399]; neurotransmitter biosynthetic process [GO:0042136]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of protein secretion [GO:0050714]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]" comp145345_c0_seq1,334,42.515,0.54032742,1,30,,1.00E-50,Q63355,Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) (Myosin heavy chain myr 2),Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) (Myosin heavy chain myr 2),GO:0005524; GO:0030898; GO:0009925; GO:0005737; GO:0070062; GO:0031941; GO:0016328; GO:0045121; GO:0003774; GO:0016459; GO:0005634; GO:0038089; GO:0090314; GO:1900748; GO:0006612; GO:2000810; GO:0060171,ATP binding; actin-dependent ATPase activity; basal plasma membrane; cytoplasm; extracellular vesicular exosome; filamentous actin; lateral plasma membrane; membrane raft; motor activity; myosin complex; nucleus; positive regulation of cell migration by vascular endothelial growth factor signaling pathway; positive regulation of protein targeting to membrane; positive regulation of vascular endothelial growth factor signaling pathway; protein targeting to membrane; regulation of tight junction assembly; stereocilium membrane,PF00612;PF00063;PF06017;,8.00E-37,CHOYP_MYO1C.2.3,,,,,,,MYO1C_RAT,Rattus norvegicus (Rat),positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration by vascular endothelial growth factor signaling pathway [GO:0038089]; positive regulation of cellular response to insulin stimulus [GO:1900078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein targeting to membrane [GO:0006612]; regulation of bicellular tight junction assembly [GO:2000810] comp145348_c0_seq1,292,35.6164,0.2167987,6,21,,5.00E-06,Q6BQ61,ATP-dependent rRNA helicase RRP3 (EC 3.6.4.-),ATP-dependent rRNA helicase RRP3 (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005634; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; nucleus; rRNA processing,PF00270;PF00271;,,,,,,,,,RRP3_DEBHA,Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" comp145350_c0_seq1,611,37.1522,0.40197152,8,49,,5.00E-28,Q8K248,4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1),4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1),GO:0003868; GO:0009072; GO:0046872,4-hydroxyphenylpyruvate dioxygenase activity; aromatic amino acid family metabolic process; metal ion binding,,1.00E-19,CHOYP_LOC576414.1.1,,,,,,,HPDL_MOUSE,Mus musculus (Mouse),aromatic amino acid family metabolic process [GO:0009072] comp145353_c0_seq1,242,61.5702,0.87569063,0,43,,2.00E-22,Q9CAX6,40S ribosomal protein S14-2,40S ribosomal protein S14-2,GO:0022627; GO:0005730; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; nucleolus; structural constituent of ribosome; translation,PF00411;,3.00E-28,CHOYP_RS14.5.6,9.00E-20,ruditapes2_lrc4878,,,,,RS142_ARATH,Arabidopsis thaliana (Mouse-ear cress),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]" comp145355_c0_seq1,454,43.3921,1.20218296,16,33,,1.00E-10,O75071,EF-hand calcium-binding domain-containing protein 14,EF-hand calcium-binding domain-containing protein 14,GO:0005509,calcium ion binding,,6.00E-15,CHOYP_EFCAB14.1.1,,,,,,,K0494_HUMAN,Homo sapiens (Human), comp145372_c0_seq1,339,49.8525,0.91192211,0,38,,1.00E-47,Q05733,Histidine decarboxylase (HDC) (EC 4.1.1.22),Histidine decarboxylase (HDC) (EC 4.1.1.22),GO:0042423; GO:0006520; GO:0004398; GO:0030170; GO:0043052,catecholamine biosynthetic process; cellular amino acid metabolic process; histidine decarboxylase activity; pyridoxal phosphate binding; thermotaxis,PF00282;,2.00E-12,CHOYP_DDC.1.1,,,,,,,DCHS_DROME,Drosophila melanogaster (Fruit fly),catecholamine biosynthetic process [GO:0042423]; cellular amino acid metabolic process [GO:0006520]; compound eye photoreceptor development [GO:0042051]; phototransduction [GO:0007602]; thermotaxis [GO:0043052] comp145380_c0_seq1,602,45.0166,0.59156475,11,62,,3.00E-85,Q9P2F8,Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2),GO:0005096; GO:0043547; GO:0051056,GTPase activator activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction,PF02145;PF11881;,4.00E-50,CHOYP_SI1L1.1.2,,,,,,,SI1L2_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056] comp145381_c0_seq1,295,41.6949,0.63316236,2,26,,2.00E-13,O75356,Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (EC 3.6.1.42) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5),Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (EC 3.6.1.42) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5),GO:0051084; GO:0046034; GO:0016049; GO:0008283; GO:0005783; GO:0005789; GO:0006096; GO:0004382; GO:0016021; GO:0006487; GO:0014066; GO:0045134,'de novo' posttranslational protein folding; ATP metabolic process; cell growth; cell proliferation; endoplasmic reticulum; endoplasmic reticulum membrane; glycolysis; guanosine-diphosphatase activity; integral to membrane; protein N-linked glycosylation; regulation of phosphatidylinositol 3-kinase cascade; uridine-diphosphatase activity,PF01150;,,,,,,,,,ENTP5_HUMAN,Homo sapiens (Human),'de novo' posttranslational protein folding [GO:0051084]; ATP metabolic process [GO:0046034]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; positive regulation of glycolytic process [GO:0045821]; protein N-linked glycosylation [GO:0006487]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp145382_c0_seq1,249,43.3735,0.77161738,5,32,,3.00E-30,Q13002,"Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)","Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)",GO:0001662; GO:0030054; GO:0006874; GO:0005234; GO:0005887; GO:0006886; GO:0015277; GO:0032983; GO:0043524; GO:0051967; GO:0043025; GO:0050806; GO:0045211; GO:0042734; GO:0019228; GO:0060079; GO:0060080; GO:0048169; GO:0048172; GO:0007268; GO:0035249,"behavioral fear response; cell junction; cellular calcium ion homeostasis; extracellular-glutamate-gated ion channel activity; integral to plasma membrane; intracellular protein transport; kainate selective glutamate receptor activity; kainate selective glutamate receptor complex; negative regulation of neuron apoptotic process; negative regulation of synaptic transmission, glutamatergic; neuronal cell body; positive regulation of synaptic transmission; postsynaptic membrane; presynaptic membrane; regulation of action potential in neuron; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential; regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; synaptic transmission; synaptic transmission, glutamatergic",PF01094;PF00060;PF10613;,2.00E-18,CHOYP_LOC663783.1.1,,,,,,,GRIK2_HUMAN,Homo sapiens (Human),"behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; glutamate receptor signaling pathway [GO:0007215]; inhibitory postsynaptic potential [GO:0060080]; intracellular protein transport [GO:0006886]; modulation of synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]; transport [GO:0006810]" comp145390_c0_seq1,239,47.2803,0.46154654,6,34,,9.00E-12,P82987,ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2),ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2),GO:0008237; GO:0005578; GO:0008270,metallopeptidase activity; proteinaceous extracellular matrix; zinc ion binding,PF07679;PF08686;PF00090;,,,,,,,,,ATL3_HUMAN,Homo sapiens (Human), comp145394_c0_seq1,437,45.9954,0.57411069,21,24,,8.00E-24,Q5XGI3,F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5),F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5),GO:0019005; GO:0031146; GO:0005506; GO:0055072; GO:0048471; GO:0016567,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; iron ion binding; iron ion homeostasis; perinuclear region of cytoplasm; protein ubiquitination,PF12937;PF01814;PF13516;,,,,,,,,,FBXL5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),iron ion homeostasis [GO:0055072]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp145396_c0_seq1,345,44.058,0.48223402,6,24,,3.00E-06,O44476,Ribonuclease Z (RNase Z) (EC 3.1.26.11) (CeELAC2) (Homolog of ELAC2 protein 1) (tRNA 3 endonuclease) (tRNase Z),Ribonuclease Z (RNase Z) (EC 3.1.26.11) (CeELAC2) (Homolog of ELAC2 protein 1) (tRNA 3 endonuclease) (tRNase Z),GO:0004519; GO:0007281; GO:0007126; GO:0046872; GO:0002119; GO:0090305; GO:0005634; GO:0040026; GO:0008033,endonuclease activity; germ cell development; meiosis; metal ion binding; nematode larval development; nucleic acid phosphodiester bond hydrolysis; nucleus; positive regulation of vulval development; tRNA processing,PF12706;,,,,,,,,,RNZ_CAEEL,Caenorhabditis elegans,"germ cell development [GO:0007281]; meiotic nuclear division [GO:0007126]; mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684]; nematode larval development [GO:0002119]; positive regulation of vulval development [GO:0040026]" comp145405_c0_seq1,452,49.7788,0.75149671,15,13,,6.00E-11,O76050,Neuralized-like protein 1A (h-neu) (h-neuralized 1) (EC 6.3.2.-) (RING finger protein 67),E3 ubiquitin-protein ligase NEURL1 (EC 6.3.2.-) (Neuralized-like protein 1A) (h-neu) (h-neuralized 1) (RING finger protein 67),GO:0007219; GO:0007420; GO:0007595; GO:0016874; GO:0007399; GO:0048471; GO:0005886; GO:0016567; GO:0009605; GO:0007519; GO:0007288; GO:0030317; GO:0008270,Notch signaling pathway; brain development; lactation; ligase activity; nervous system development; perinuclear region of cytoplasm; plasma membrane; protein ubiquitination; response to external stimulus; skeletal muscle tissue development; sperm axoneme assembly; sperm motility; zinc ion binding,PF07177;,,,,,,,,,NEU1A_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; lactation [GO:0007595]; negative regulation of cell proliferation [GO:0008285]; negative regulation of Notch signaling pathway [GO:0045746]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of synapse maturation [GO:0090129]; protein monoubiquitination [GO:0006513]; skeletal muscle tissue development [GO:0007519]; sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317] comp145407_c0_seq1,441,48.7528,0.51075818,4,40,,7.00E-29,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,2.00E-58,CHOYP_LOC100377364.2.2,,,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp145416_c0_seq1,765,42.2222,0.38341356,35,51,,2.00E-49,Q2TAA2,Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-),Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-),GO:0016788; GO:0016042,"hydrolase activity, acting on ester bonds; lipid catabolic process",PF13472;,,,,,,,,,IAH1_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042] comp145418_c0_seq1,493,39.7566,0.4924699,5,46,,1.00E-21,Q8CFG5,Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3],Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3],GO:0005246; GO:0046872; GO:0005245; GO:0005891,calcium channel regulator activity; metal ion binding; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08473;PF13768;PF08399;,,,,,,,,,CA2D3_RAT,Rattus norvegicus (Rat),calcium ion transport [GO:0006816]; regulation of calcium ion transport [GO:0051924] comp145422_c0_seq1,276,39.1304,0.52722428,3,35,,1.00E-07,Q0IHV1,Inverted formin-2,Inverted formin-2,GO:0030036,actin cytoskeleton organization,PF06367;PF06371;PF02181;PF02205;,,,,,,,,,INF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),actin cytoskeleton organization [GO:0030036] comp145423_c0_seq1,281,43.0605,0.47959791,9,20,,2.00E-22,O46469,Regulator of G-protein signaling 9 (RGS9),Regulator of G-protein signaling 9 (RGS9),GO:0007186; GO:0005096; GO:0005737; GO:0005834; GO:0035556; GO:0097381; GO:0004871; GO:0038032; GO:0007601,G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; heterotrimeric G-protein complex; intracellular signal transduction; photoreceptor disc membrane; signal transducer activity; termination of G-protein coupled receptor signaling pathway; visual perception,PF00610;PF00631;PF00615;,,,,,,,,,RGS9_BOVIN,Bos taurus (Bovine),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; visual perception [GO:0007601] comp145429_c0_seq1,274,44.5255,0.89070012,0,31,,4.00E-06,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp145430_c0_seq1,663,45.7014,0.61045581,16,39,,3.00E-83,Q62925,Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),GO:0005524; GO:0004706; GO:0005737; GO:0016020; GO:0032232; GO:0018105; GO:0043507; GO:0043065; GO:0045944; GO:0050434; GO:0046777; GO:0051259; GO:0000209; GO:0042787; GO:0006970; GO:0046625; GO:0004842; GO:0008270,ATP binding; JUN kinase kinase kinase activity; cytoplasm; membrane; negative regulation of actin filament bundle assembly; peptidyl-serine phosphorylation; positive regulation of JUN kinase activity; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; protein autophosphorylation; protein oligomerization; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to osmotic stress; sphingolipid binding; ubiquitin-protein ligase activity; zinc ion binding,PF00069;,4.00E-83,CHOYP_MAP3K1.1.1,,,,,,,M3K1_RAT,Rattus norvegicus (Rat),activation of JNKK activity [GO:0007256]; activation of MAPKK activity [GO:0000186]; MAPK cascade [GO:0000165]; negative regulation of actin filament bundle assembly [GO:0032232]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to osmotic stress [GO:0006970] comp145454_c0_seq1,327,45.2599,0.48235745,3,25,,4.00E-28,Q5EAW4,Protein MCM10 homolog,Protein MCM10 homolog,GO:0003677; GO:0006260; GO:0046872; GO:0005634,DNA binding; DNA replication; metal ion binding; nucleus,PF09332;PF09329;,,,,,,,,,MCM10_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260] comp145458_c0_seq1,509,39.4892,0.46410695,11,25,,4.00E-30,O54922,Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70),Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70),GO:0005829; GO:0000145; GO:0006887; GO:0005886; GO:0015031,cytosol; exocyst; exocytosis; plasma membrane; protein transport,PF03081;,3.00E-19,CHOYP_LOC574569.1.1,,,,,,,EXOC7_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; protein transport [GO:0015031] comp145476_c0_seq1,389,42.6735,0.28409279,5,29,,4.00E-18,O54922,Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70),Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70),GO:0005829; GO:0000145; GO:0006887; GO:0005886; GO:0015031,cytosol; exocyst; exocytosis; plasma membrane; protein transport,PF03081;,,,,,,,,,EXOC7_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; protein transport [GO:0015031] comp145479_c0_seq1,211,44.5498,0.68294217,3,18,,4.00E-13,Q8WVF1,Protein OSCP1 (hOSCP1) (Organic solute transport protein 1) (Oxidored-nitro domain-containing protein 1),Protein OSCP1 (hOSCP1) (Organic solute transport protein 1) (Oxidored-nitro domain-containing protein 1),GO:0009925; GO:0006810,basal plasma membrane; transport,PF10188;,,,,,,,,,OSCP1_HUMAN,Homo sapiens (Human),positive regulation of protein targeting to mitochondrion [GO:1903955]; transport [GO:0006810] comp145483_c0_seq1,207,47.8261,0.59429958,0,28,,6.00E-19,O70489,Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-),Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-),GO:0006464; GO:0005764; GO:0008474,cellular protein modification process; lysosome; palmitoyl-(protein) hydrolase activity,PF02089;,,,,,,,,,PPT2_RAT,Rattus norvegicus (Rat), comp145491_c0_seq1,282,41.1348,1.37924366,0,33,,9.00E-10,Q91VN0,Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),GO:0044332; GO:0042813; GO:0060612; GO:0060033; GO:0009952; GO:1902262; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042074; GO:0060764; GO:0042632; GO:0008203; GO:0015026; GO:0048596; GO:0042733; GO:0060059; GO:0006897; GO:0005783; GO:0035426; GO:0001702; GO:0016021; GO:0005739; GO:0002076; GO:0005886; GO:0033690; GO:0051091; GO:0045944; GO:0043235; GO:0042981; GO:0046850; GO:0045598; GO:0061178; GO:0030278; GO:0061304; GO:0035019,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; adipose tissue development; anatomical structure regression; anterior/posterior pattern specification; apoptotic process involved in patterning of blood vessels; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cell migration involved in gastrulation; cell-cell signaling involved in mammary gland development; cholesterol homeostasis; cholesterol metabolic process; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; extracellular matrix-cell signaling; gastrulation with mouth forming second; integral to membrane; mitochondrion; osteoblast development; plasma membrane; positive regulation of osteoblast proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of apoptotic process; regulation of bone remodeling; regulation of fat cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of ossification; retinal blood vessel morphogenesis; somatic stem cell maintenance,PF00057;PF00058;,,,,,,,,,LRP5_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp145500_c0_seq1,297,45.4545,0.60955236,12,22,,1.00E-27,Q3TLI0,Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1),GO:0005794; GO:0016192,Golgi apparatus; vesicle-mediated transport,PF12584;,,,,,,,,,TPC10_MOUSE,Mus musculus (Mouse),early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891] comp145505_c0_seq1,246,40.6504,0.59304701,8,15,,6.00E-32,F6PTN1,Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A),Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A),GO:0016055; GO:0017147; GO:0060322; GO:0031301; GO:0005887; GO:0046872; GO:0004222; GO:0030178; GO:0018158; GO:0006508,Wnt receptor signaling pathway; Wnt-protein binding; head development; integral to organelle membrane; integral to plasma membrane; metal ion binding; metalloendopeptidase activity; negative regulation of Wnt receptor signaling pathway; protein oxidation; proteolysis,PF01963;,,,,,,,,,TIKI1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),head development [GO:0060322]; negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508]; Wnt signaling pathway [GO:0016055] comp145519_c0_seq1,379,48.0211,0.82639213,10,35,,3.00E-14,Q96NG3,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),GO:0005737,cytoplasm,PF13181;,,,,,,,,,TTC25_HUMAN,Homo sapiens (Human), comp145529_c0_seq1,317,46.3722,0.35333685,1,42,,5.00E-17,P46939,Utrophin (Dystrophin-related protein 1) (DRP-1),Utrophin (Dystrophin-related protein 1) (DRP-1),GO:0003779; GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0016010; GO:0030175; GO:0006936; GO:0007517; GO:0031594; GO:0005634; GO:0005886; GO:0001954; GO:0045211; GO:0043234; GO:2000649; GO:0008270,actin binding; calcium ion binding; cell junction; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; filopodium; muscle contraction; muscle organ development; neuromuscular junction; nucleus; plasma membrane; positive regulation of cell-matrix adhesion; postsynaptic membrane; protein complex; regulation of sodium ion transmembrane transporter activity; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00569;,,,,,,,,,UTRO_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649] comp145543_c0_seq1,302,46.0265,0.7557906,3,22,,4.00E-07,D3ZJP6,Unconventional myosin-X (Unconventional myosin-10),Unconventional myosin-X (Unconventional myosin-10),GO:0005524; GO:0051015; GO:0030898; GO:0005938; GO:0030705; GO:0005829; GO:0031527; GO:0032433; GO:0030027; GO:0016459; GO:0005547; GO:0060002; GO:0008360; GO:0051489; GO:0001726,"ATP binding; actin filament binding; actin-dependent ATPase activity; cell cortex; cytoskeleton-dependent intracellular transport; cytosol; filopodium membrane; filopodium tip; lamellipodium; myosin complex; phosphatidylinositol-3,4,5-trisphosphate binding; plus-end directed microfilament motor activity; regulation of cell shape; regulation of filopodium assembly; ruffle",PF00373;PF00612;PF16735;PF00063;PF00784;PF00169;,1.00E-21,CHOYP_MYO22.2.2,,,,,,,MYO10_RAT,Rattus norvegicus (Rat),cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489] comp145555_c0_seq1,318,44.3396,0.3883967,12,19,,4.00E-25,Q7KTX8,Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240),Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240),GO:0001104; GO:0045165; GO:0022416; GO:0048749; GO:0009790; GO:0036011; GO:0016592; GO:0030177; GO:0045498; GO:0048190,RNA polymerase II transcription cofactor activity; cell fate commitment; chaeta development; compound eye development; embryo development; imaginal disc-derived leg segmentation; mediator complex; positive regulation of Wnt receptor signaling pathway; sex comb development; wing disc dorsal/ventral pattern formation,PF06333;PF11597;,2.00E-18,CHOYP_PHUM_PHUM174820.1.1,,,,,,,MED13_DROME,Drosophila melanogaster (Fruit fly),cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sex comb development [GO:0045498]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] comp145560_c0_seq1,284,44.3662,0.29193704,13,10,,2.00E-10,Q8IWA6,Coiled-coil domain-containing protein 60,Coiled-coil domain-containing protein 60,,,PF15769;,,,,,,,,,CCD60_HUMAN,Homo sapiens (Human), comp145564_c0_seq1,318,36.7925,0.4661063,14,17,,4.00E-12,Q60803,TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN),TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN),GO:0035631; GO:0008063; GO:0006915; GO:0005768; GO:0045087; GO:0009898; GO:0032088; GO:0042981; GO:0050688; GO:0032648; GO:0030162; GO:0002224; GO:0033209; GO:0004842; GO:0008270,CD40 receptor complex; Toll signaling pathway; apoptotic process; endosome; innate immune response; internal side of plasma membrane; negative regulation of NF-kappaB transcription factor activity; regulation of apoptotic process; regulation of defense response to virus; regulation of interferon-beta production; regulation of proteolysis; toll-like receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,TRAF3_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp145575_c0_seq1,519,43.1599,0.71940371,10,41,,,,,,,,,1.00E-61,CHOYP_GBB.2.2,,,,,,,,, comp145576_c0_seq1,277,35.0181,0.23760993,9,8,,,,,,,,,,,2.00E-21,ruditapes2_c1163,,,,,,, comp145578_c0_seq1,255,41.9608,0.71559451,2,21,,4.00E-42,Q9WVL6,Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3),Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3),GO:0001888; GO:0015012; GO:0016021; GO:0031227; GO:0046872,glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; metal ion binding,PF03016;PF09258;,9.00E-29,CHOYP_LOC100121031.2.2,,,,,,,EXTL3_MOUSE,Mus musculus (Mouse),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] comp145586_c0_seq1,246,41.8699,0.46923268,0,26,,2.00E-16,B5DF45,TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),GO:0035631; GO:0007249; GO:0007254; GO:0050852; GO:0042088; GO:0007250; GO:0019886; GO:0045453; GO:0005938; GO:0048468; GO:0005829; GO:0070498; GO:0009898; GO:0005811; GO:0043011; GO:0000122; GO:0001843; GO:0031965; GO:0042475; GO:0001503; GO:0030316; GO:0048471; GO:0043123; GO:0043507; GO:0051092; GO:0002726; GO:0042102; GO:0045084; GO:0032743; GO:0045410; GO:0031666; GO:0045672; GO:0048661; GO:0045944; GO:2000679; GO:0070534; GO:0051865; GO:0043234; GO:0006461; GO:0042981; GO:0051023; GO:0004871; GO:0004842; GO:0008270,CD40 receptor complex; I-kappaB kinase/NF-kappaB cascade; JNK cascade; T cell receptor signaling pathway; T-helper 1 type immune response; activation of NF-kappaB-inducing kinase activity; antigen processing and presentation of exogenous peptide antigen via MHC class II; bone resorption; cell cortex; cell development; cytosol; interleukin-1-mediated signaling pathway; internal side of plasma membrane; lipid particle; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nuclear membrane; odontogenesis of dentin-containing tooth; ossification; osteoclast differentiation; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell cytokine production; positive regulation of T cell proliferation; positive regulation of interleukin-12 biosynthetic process; positive regulation of interleukin-2 production; positive regulation of interleukin-6 biosynthetic process; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of osteoclast differentiation; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription regulatory region DNA binding; protein K63-linked ubiquitination; protein autoubiquitination; protein complex; protein complex assembly; regulation of apoptotic process; regulation of immunoglobulin secretion; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,,,,,,,TRAF6_RAT,Rattus norvegicus (Rat),activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein complex assembly [GO:0006461]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088] comp145598_c0_seq1,251,47.4104,0.79246541,1,31,,,,,,,,,2.00E-17,CHOYP_LOC100378520.1.2,,,,,,,,, comp145603_c0_seq1,276,55.0725,0.91299814,9,23,,,,,,,,,4.00E-14,CHOYP_contig_010708,,,,,,,,, comp145607_c0_seq1,420,50.2381,0.51303253,5,27,,3.00E-67,Q5F364,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,1.00E-55,CHOYP_MRP1.5.10,,,,,,,MRP1_CHICK,Gallus gallus (Chicken), comp145614_c0_seq1,223,42.6009,0.69504944,1,20,,4.00E-15,Q2TBU3,Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28),Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28),GO:0006888; GO:0000139; GO:0005801; GO:0016021; GO:0015031,ER to Golgi vesicle-mediated transport; Golgi membrane; cis-Golgi network; integral to membrane; protein transport,,,,,,,,,,GOSR1_BOVIN,Bos taurus (Bovine),"ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of vesicle targeting, to, from or within Golgi [GO:0048209]; vesicle fusion [GO:0006906]" comp145618_c0_seq1,618,39.1586,0.71198714,26,22,,7.00E-68,Q0IIF6,Fas apoptotic inhibitory molecule 1,Fas apoptotic inhibitory molecule 1,GO:0006915; GO:0005737; GO:0043066,apoptotic process; cytoplasm; negative regulation of apoptotic process,PF06905;,2.00E-30,CHOYP_FAIM1.1.1,,,,,,,FAIM1_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066] comp145634_c0_seq1,296,43.5811,0.58379045,4,31,,1.00E-14,Q10836,Thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) (TRH-degrading ectoenzyme) (EC 3.4.19.6) (Pyroglutamyl-peptidase II) (PAP-II) (TRH-specific aminopeptidase) (Thyroliberinase),Thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) (TRH-degrading ectoenzyme) (EC 3.4.19.6) (Pyroglutamyl-peptidase II) (PAP-II) (TRH-specific aminopeptidase) (Thyroliberinase),GO:0004177; GO:0016021; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; integral to membrane; metallopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,TRHDE_RAT,Rattus norvegicus (Rat),cell-cell signaling [GO:0007267]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] comp145646_c0_seq1,686,42.8571,1.24358584,25,56,,1.00E-09,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp145651_c0_seq1,341,41.0557,0.77027689,7,29,,1.00E-44,O70422,General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit),General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit),GO:0004003; GO:0008353; GO:0000439; GO:0005675; GO:0006289; GO:0006355; GO:0006366,"ATP-dependent DNA helicase activity; RNA polymerase II carboxy-terminal domain kinase activity; core TFIIH complex; holo TFIIH complex; nucleotide-excision repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter",PF03849;,5.00E-33,CHOYP_BRAFLDRAFT_57175.1.1,,,,,,,TF2H4_MOUSE,Mus musculus (Mouse),nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription from RNA polymerase II promoter [GO:0006366] comp145655_c0_seq1,484,41.5289,0.91292246,6,44,,2.00E-30,Q7SIH1,Alpha-2-macroglobulin (Alpha-2-M),Alpha-2-macroglobulin (Alpha-2-M),GO:0005615; GO:0070062; GO:0001869; GO:0010951; GO:0004867; GO:0048863,"extracellular space; extracellular vesicular exosome; negative regulation of complement activation, lectin pathway; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity; stem cell differentiation",PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,A2MG_BOVIN,Bos taurus (Bovine),"negative regulation of complement activation, lectin pathway [GO:0001869]; stem cell differentiation [GO:0048863]" comp145656_c0_seq1,348,44.8276,0.80322873,24,20,,1.00E-09,O15432,Probable low affinity copper uptake protein 2 (Copper transporter 2) (hCTR2) (Solute carrier family 31 member 2),Probable low affinity copper uptake protein 2 (Copper transporter 2) (hCTR2) (Solute carrier family 31 member 2),GO:0005375; GO:0005887,copper ion transmembrane transporter activity; integral to plasma membrane,PF04145;,,,,,,,,,COPT2_HUMAN,Homo sapiens (Human),cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; regulation of copper ion transmembrane transport [GO:1902311] comp145660_c0_seq1,236,42.3729,1.00596034,0,30,,7.00E-18,Q04721,Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)],GO:0000139; GO:0007220; GO:0061314; GO:0006915; GO:0060413; GO:0046849; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0005789; GO:0005576; GO:0030097; GO:0005887; GO:0043066; GO:0008285; GO:0007399; GO:0005654; GO:0046579; GO:0003184; GO:0004872; GO:0006355; GO:0019827; GO:0006367,"Golgi membrane; Notch receptor processing; Notch signaling involved in heart development; apoptotic process; atrial septum morphogenesis; bone remodeling; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; endoplasmic reticulum membrane; extracellular region; hemopoiesis; integral to plasma membrane; negative regulation of apoptotic process; negative regulation of cell proliferation; nervous system development; nucleoplasm; positive regulation of Ras protein signal transduction; pulmonary valve morphogenesis; receptor activity; regulation of transcription, DNA-dependent; stem cell maintenance; transcription initiation from RNA polymerase II promoter",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; hemopoiesis [GO:0030097]; marginal zone B cell differentiation [GO:0002315]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; pulmonary valve morphogenesis [GO:0003184]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp145666_c0_seq1,323,39.0093,0.33333653,11,13,,4.00E-11,A4QN56,Sodium-dependent glucose transporter 1,Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B),GO:0016324; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,NAGT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp145672_c0_seq1,220,48.6364,0.89839255,0,31,,,,,,,,,2.00E-18,CHOYP_ARALYDRAFT_497139.1.1,,,,,,,,, comp145674_c0_seq1,230,47.3913,0.64616606,1,20,,7.00E-19,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,9.00E-28,CHOYP_LOC100378579.1.1,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp145688_c0_seq1,238,36.5546,1.2919147,0,25,,9.00E-12,Q8JG30,Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-),Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-),GO:0005737; GO:0008202; GO:0008146,cytoplasm; steroid metabolic process; sulfotransferase activity,PF00685;,,,,,,,,,ST1B1_CHICK,Gallus gallus (Chicken),steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] comp145702_c0_seq1,314,43.3121,0.27541263,4,33,,2.00E-13,Q28EC1,Ras-GEF domain-containing family member 1B,Ras-GEF domain-containing family member 1B,GO:0005088; GO:0005622; GO:0051056; GO:0007264,Ras guanyl-nucleotide exchange factor activity; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00617;PF00618;,,,,,,,,,RGF1B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),small GTPase mediated signal transduction [GO:0007264] comp145707_c0_seq1,427,49.6487,1.04183767,10,22,,7.00E-43,Q9QZQ0,Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6),Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6),GO:0003677; GO:0005737; GO:0007626; GO:0042711; GO:0005634; GO:0045893; GO:0004871; GO:0001964; GO:0006351,"DNA binding; cytoplasm; locomotory behavior; maternal behavior; nucleus; positive regulation of transcription, DNA-dependent; signal transducer activity; startle response; transcription, DNA-dependent",PF00989;PF08447;,2.00E-39,CHOYP_TRH.1.1,,,,,,,NPAS3_MOUSE,Mus musculus (Mouse),"developmental process [GO:0032502]; locomotory behavior [GO:0007626]; maternal behavior [GO:0042711]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; startle response [GO:0001964]; transcription, DNA-templated [GO:0006351]" comp145712_c0_seq1,239,43.5146,0.89587235,1,21,,5.00E-06,Q9VJB6,Putative neural-cadherin 2 (Cadherin-N2) (dN2-cadherin),Putative neural-cadherin 2 (Cadherin-N2) (dN2-cadherin),GO:0045467; GO:0045463; GO:0048846; GO:0005509; GO:0016339; GO:0050839; GO:0007156; GO:0005887; GO:0016318; GO:0004872,R7 cell development; R8 cell development; axon extension involved in axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; homophilic cell adhesion; integral to plasma membrane; ommatidial rotation; receptor activity,PF00028;PF01049;PF00008;PF02210;,,,,,,,,,CADN2_DROME,Drosophila melanogaster (Fruit fly),axon extension involved in axon guidance [GO:0048846]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463] comp145737_c0_seq1,311,46.6238,0.6842176,8,16,,3.00E-36,B1AVY7,Kinesin-like protein KIF16B,Kinesin-like protein KIF16B,GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,1.00E-46,CHOYP_KI16B.2.3,,,,,,,KI16B_MOUSE,Mus musculus (Mouse),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp145741_c0_seq1,243,48.9712,1.01728941,0,36,,2.00E-18,O43315,Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1),Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1),GO:0005275; GO:0016323; GO:0015722; GO:0046943; GO:0071320; GO:0007588; GO:0015254; GO:0006955; GO:0005887; GO:0043231; GO:0008152; GO:0015288; GO:0005345; GO:0005350; GO:0046689; GO:0006970; GO:0015250; GO:0030104,amine transmembrane transporter activity; basolateral plasma membrane; canalicular bile acid transport; carboxylic acid transmembrane transporter activity; cellular response to cAMP; excretion; glycerol channel activity; immune response; integral to plasma membrane; intracellular membrane-bounded organelle; metabolic process; porin activity; purine nucleobase transmembrane transporter activity; pyrimidine nucleobase transmembrane transporter activity; response to mercury ion; response to osmotic stress; water channel activity; water homeostasis,PF00230;,,,,,,,,,AQP9_HUMAN,Homo sapiens (Human),amine transport [GO:0015837]; canalicular bile acid transport [GO:0015722]; carboxylic acid transport [GO:0046942]; cellular response to cAMP [GO:0071320]; cellular water homeostasis [GO:0009992]; excretion [GO:0007588]; glycerol transport [GO:0015793]; immune response [GO:0006955]; metabolic process [GO:0008152]; polyol transport [GO:0015791]; purine nucleobase transport [GO:0006863]; pyrimidine nucleobase transport [GO:0015855]; response to mercury ion [GO:0046689]; response to organic substance [GO:0010033]; response to osmotic stress [GO:0006970]; transport [GO:0006810]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104]; water transport [GO:0006833] comp145747_c0_seq1,342,43.5673,0.37459366,11,28,,5.00E-18,Q0KI50,"Dystrophin, isoform D (Protein detached)","Dystrophin, isoform D (Protein detached)",GO:0003779; GO:0005509; GO:0005737; GO:0005856; GO:0016010; GO:0030010; GO:0008586; GO:0007474; GO:0046716; GO:0007517; GO:0007274; GO:0046928; GO:0048172; GO:0042383; GO:0005198; GO:0045202; GO:0008270,actin binding; calcium ion binding; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; establishment of cell polarity; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; muscle cell cellular homeostasis; muscle organ development; neuromuscular synaptic transmission; regulation of neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity; sarcolemma; structural molecule activity; synapse; zinc ion binding,PF09068;PF09069;PF00569;,,,,,,,,,DMDD_DROME,Drosophila melanogaster (Fruit fly),establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172] comp145759_c0_seq1,208,46.6346,0.80044403,6,12,,3.00E-13,Q53G44,Interferon-induced protein 44-like,Interferon-induced protein 44-like,GO:0005737; GO:0051607; GO:0006955,cytoplasm; defense response to virus; immune response,PF01926;,9.00E-15,CHOYP_LOC101165968.2.7,,,,,,,IF44L_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607] comp14575_c0_seq1,277,49.8195,0.41940202,3,1,,3.00E-13,Q6ZMP0,Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6),Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6),GO:0048251; GO:0004222; GO:0001527,elastic fiber assembly; metalloendopeptidase activity; microfibril,PF05986;PF08686;PF00090;,,,,,,,,,THSD4_HUMAN,Homo sapiens (Human),elastic fiber assembly [GO:0048251] comp145764_c0_seq1,224,34.8214,0.50944412,1,22,,,,,,,,,1.00E-14,CHOYP_LOC100370477.2.2,,,,,,,,, comp145770_c0_seq1,301,47.1761,0.48080133,5,15,,4.00E-19,P53349,Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),GO:0005524; GO:0008545; GO:0004709; GO:0000186; GO:0008637; GO:0005829; GO:0003382; GO:0061029; GO:0030838; GO:0030334; GO:0007179; GO:0042060; GO:0008270,ATP binding; JUN kinase kinase activity; MAP kinase kinase kinase activity; activation of MAPKK activity; apoptotic mitochondrial changes; cytosol; epithelial cell morphogenesis; eyelid development in camera-type eye; positive regulation of actin filament polymerization; regulation of cell migration; transforming growth factor beta receptor signaling pathway; wound healing; zinc ion binding,PF00069;PF04434;,3.00E-35,CHOYP_MAP3K1.1.1,,,,,,,M3K1_MOUSE,Mus musculus (Mouse),activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060] comp145772_c0_seq1,373,35.6568,0.59772119,8,24,,1.00E-09,Q9VUL9,"Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)","Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)",GO:0033932; GO:0032580; GO:0005797; GO:0036071; GO:0018392; GO:0016021; GO:0007399; GO:0006486,"1,3-alpha-L-fucosidase activity; Golgi cisterna membrane; Golgi medial cisterna; N-glycan fucosylation; glycoprotein 3-alpha-L-fucosyltransferase activity; integral to membrane; nervous system development; protein glycosylation",PF17039;PF00852;,,,,,,,,,FUCTA_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] comp145775_c0_seq1,230,64.7826,0.95731539,0,26,,3.00E-07,Q82LU9,Crotonyl-CoA reductase (EC 1.3.1.86),Crotonyl-CoA reductase (EC 1.3.1.86),GO:0050661; GO:0043880; GO:0006631; GO:0008270,NADP binding; crotonyl-CoA reductase activity; fatty acid metabolic process; zinc ion binding,PF08240;PF00107;,,,,,,,,,CCRA2_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),fatty acid metabolic process [GO:0006631] comp145786_c0_seq1,221,41.1765,0.21765152,1,16,,3.00E-16,Q6ZT12,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0009790; GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,embryo development; in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,3.00E-15,CHOYP_UBR3.1.1,,,,,,,UBR3_HUMAN,Homo sapiens (Human),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp145787_c0_seq1,298,43.2886,1.36564038,0,30,,,,,,,,,7.00E-12,CHOYP_contig_014969,,,,,,,,, comp145796_c0_seq1,326,37.7301,0.97427786,4,23,,1.00E-06,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp145801_c0_seq1,234,43.1624,0.18740374,4,21,,,,,,,,,5.00E-19,CHOYP_IKZF3.2.2,,,,,,,,, comp145808_c0_seq1,215,41.8605,0.75262952,0,26,,5.00E-18,Q66T02,Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX),Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX),GO:0005089; GO:0005911; GO:0030139; GO:0035767; GO:0030027; GO:0048471; GO:0005543; GO:0005886; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell-cell junction; endocytic vesicle; endothelial cell chemotaxis; lamellipodium; perinuclear region of cytoplasm; phospholipid binding; plasma membrane; regulation of Rho protein signal transduction,PF00621;,1.00E-25,CHOYP_BRAFLDRAFT_124569.1.1,,,,,,,PKHG5_MOUSE,Mus musculus (Mouse),endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of Rho protein signal transduction [GO:0035023] comp145830_c0_seq1,265,47.5472,0.6033352,3,26,,2.00E-16,Q96WW4,Invasion protein 1,Invasion protein 1,GO:0007166; GO:0005783; GO:0016021; GO:0005770; GO:0005886; GO:0010570,cell surface receptor signaling pathway; endoplasmic reticulum; integral to membrane; late endosome; plasma membrane; regulation of filamentous growth,PF03381;,,,,,,,,,YNI7_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cell surface receptor signaling pathway [GO:0007166]; regulation of filamentous growth [GO:0010570] comp145857_c0_seq1,276,38.7681,0.39487332,12,11,,,,,,,,,1.00E-72,CHOYP_EF1A.4.4,5.00E-11,ruditapes2_c1686,,,,,,, comp145872_c0_seq1,322,44.7205,0.31371709,9,19,,6.00E-62,Q27955,Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2),Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2),GO:0005737; GO:0016021; GO:0044224; GO:0005249,cytoplasm; integral to membrane; juxtaparanode region of axon; voltage-gated potassium channel activity,PF00248;,2.00E-75,CHOYP_BRAFLDRAFT_67317.2.2,,,,,,,KCAB2_BOVIN,Bos taurus (Bovine),hematopoietic progenitor cell differentiation [GO:0002244]; NADPH oxidation [GO:0070995]; neuromuscular process [GO:0050905]; oxidation-reduction process [GO:0055114]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008] comp145876_c0_seq1,338,42.3077,0.60178042,12,13,,2.00E-29,Q0GGX2,Zinc finger protein 541 (Spermatogenic cell HDAC-interacting protein 1),Zinc finger protein 541 (Spermatogenic cell HDAC-interacting protein 1),GO:0003677; GO:0030154; GO:0003682; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0007283; GO:0006351,"DNA binding; cell differentiation; chromatin binding; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF01448;PF13912;,4.00E-34,CHOYP_LOC100901719.1.1,,,,,,,ZN541_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp145885_c0_seq1,483,48.6542,0.46278516,16,18,,,,,,,,,3.00E-19,CHOYP_LOC101021639.1.1,,,,,,,,, comp145894_c0_seq1,365,39.1781,0.35840457,11,20,,6.00E-13,Q96JJ3,Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A),Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A),GO:0038096; GO:0006915; GO:0060326; GO:0005856; GO:0005829; GO:0045087; GO:0016020; GO:0005543,Fc-gamma receptor signaling pathway involved in phagocytosis; apoptotic process; cell chemotaxis; cytoskeleton; cytosol; innate immune response; membrane; phospholipid binding,PF11841;PF04727;PF16457;,,,,,,,,,ELMO2_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell chemotaxis [GO:0060326]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp145895_c0_seq1,532,42.8571,0.49249423,11,33,,5.00E-21,P26769,Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2),Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2) (AC2),GO:0005524; GO:0008179; GO:0007188; GO:0008294; GO:0005737; GO:0030425; GO:0016021; GO:0005622; GO:0035556; GO:0045121; GO:0046872; GO:0005886; GO:0043234; GO:0046982,ATP binding; adenylate cyclase binding; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; calcium- and calmodulin-responsive adenylate cyclase activity; cytoplasm; dendrite; integral to membrane; intracellular; intracellular signal transduction; membrane raft; metal ion binding; plasma membrane; protein complex; protein heterodimerization activity,PF16214;PF06327;PF00211;,3.00E-20,CHOYP_APLB.1.1,,,,,,,ADCY2_RAT,Rattus norvegicus (Rat),adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to forskolin [GO:1904322] comp145898_c0_seq1,302,34.106,0.58359654,1,31,,,,,,,,,7.00E-12,CHOYP_LOC100877554.1.2,,,,,,,,, comp145901_c0_seq1,519,46.2428,0.73368879,12,39,,2.00E-43,Q8IZD9,Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP),Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP),GO:0005737; GO:0005085; GO:0007264,cytoplasm; guanyl-nucleotide exchange factor activity; small GTPase mediated signal transduction,PF06920;PF14429;PF16172;PF07653;,6.00E-22,CHOYP_DOCK3.2.2,,,,,,,DOCK3_HUMAN,Homo sapiens (Human),small GTPase mediated signal transduction [GO:0007264] comp145931_c0_seq1,413,44.3099,0.34623859,27,11,,4.00E-47,Q08C93,Monoacylglycerol lipase ABHD12 (EC 3.1.1.23) (Abhydrolase domain-containing protein 12),Monoacylglycerol lipase ABHD12 (EC 3.1.1.23) (Abhydrolase domain-containing protein 12),GO:0047372; GO:0016021,acylglycerol lipase activity; integral to membrane,PF12146;,8.00E-13,CHOYP_ABHD12.1.1,,,,,,,ABD12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),acylglycerol catabolic process [GO:0046464] comp145942_c0_seq1,254,41.7323,1.02187376,0,24,,1.00E-11,Q9JKF4,C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2),C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2),GO:0030246; GO:0050832; GO:0045087; GO:0016021; GO:0043123; GO:0050715,carbohydrate binding; defense response to fungus; innate immune response; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cytokine secretion,PF00059;,,,,,,,,,CLC6A_MOUSE,Mus musculus (Mouse),adaptive immune response [GO:0002250]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] comp145953_c0_seq1,477,45.0734,0.25105152,13,22,,2.00E-44,Q95M30,Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK),Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK),GO:0005524; GO:0005794; GO:0005901; GO:0005856; GO:0005829; GO:0006887; GO:0031234; GO:0005925; GO:0006954; GO:0045087; GO:0005764; GO:0004715; GO:0005634; GO:0006909; GO:2000251; GO:0008284; GO:0046777; GO:0004713; GO:0008360; GO:0050764; GO:0071801; GO:0030133,ATP binding; Golgi apparatus; caveola; cytoskeleton; cytosol; exocytosis; extrinsic to internal side of plasma membrane; focal adhesion; inflammatory response; innate immune response; lysosome; non-membrane spanning protein tyrosine kinase activity; nucleus; phagocytosis; positive regulation of actin cytoskeleton reorganization; positive regulation of cell proliferation; protein autophosphorylation; protein tyrosine kinase activity; regulation of cell shape; regulation of phagocytosis; regulation of podosome assembly; transport vesicle,PF07714;PF00017;PF00018;,3.00E-44,CHOYP_SRC1.1.1,,,,,,,HCK_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),exocytosis [GO:0006887]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; regulation of cell shape [GO:0008360]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801] comp145956_c0_seq1,208,46.6346,0.82501907,0,33,,4.00E-11,Q80T91,Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11),Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11),GO:0016323; GO:0034109; GO:0016021; GO:0010842,basolateral plasma membrane; homotypic cell-cell adhesion; integral to membrane; retina layer formation,PF12661;PF00053;,,,,,,,,,MEG11_MOUSE,Mus musculus (Mouse),homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842] comp145965_c0_seq1,201,50.7463,1.1081779,0,27,,6.00E-13,Q54GE1,Beta-galactosidase 1 (EC 3.2.1.23) (Acid beta-galactosidase 1) (Lactase 1),Beta-galactosidase 1 (EC 3.2.1.23) (Acid beta-galactosidase 1) (Lactase 1),GO:0004565; GO:0005975; GO:0005764,beta-galactosidase activity; carbohydrate metabolic process; lysosome,PF01301;,,,,,,,,,BGAL1_DICDI,Dictyostelium discoideum (Slime mold),carbohydrate metabolic process [GO:0005975] comp145991_c0_seq1,202,55.4455,1.16856078,0,24,,8.00E-13,Q9SLQ8,"Oxygen-evolving enhancer protein 2, chloroplastic (OEE2) (23 kDa subunit of oxygen evolving system of photosystem II) (23 kDa thylakoid membrane protein) (OEC 23 kDa subunit) (OEC23)","Oxygen-evolving enhancer protein 2, chloroplastic (OEE2) (23 kDa subunit of oxygen evolving system of photosystem II) (23 kDa thylakoid membrane protein) (OEC 23 kDa subunit) (OEC23)",GO:0005509; GO:0009535; GO:0019898; GO:0015979; GO:0009654,calcium ion binding; chloroplast thylakoid membrane; extrinsic to membrane; photosynthesis; photosystem II oxygen evolving complex,PF01789;,,,,,,,,,PSBP_CUCSA,Cucumis sativus (Cucumber),photosynthesis [GO:0015979] comp145997_c0_seq1,344,42.1512,0.35104082,9,15,,3.00E-30,Q9NY47,Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2],Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2],GO:0006112; GO:0046872; GO:0048747; GO:0007528; GO:0005886; GO:0046622; GO:0050796; GO:0040014; GO:0060024; GO:0044281; GO:0005245; GO:0005891,energy reserve metabolic process; metal ion binding; muscle fiber development; neuromuscular junction development; plasma membrane; positive regulation of organ growth; regulation of insulin secretion; regulation of multicellular organism growth; rhythmic synaptic transmission; small molecule metabolic process; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08473;PF00092;PF08399;,6.00E-26,CHOYP_CA2D2.2.2,,,,,,,CA2D2_HUMAN,Homo sapiens (Human),cardiac conduction [GO:0061337]; muscle fiber development [GO:0048747]; neuromuscular junction development [GO:0007528]; positive regulation of organ growth [GO:0046622]; regulation of insulin secretion [GO:0050796]; regulation of multicellular organism growth [GO:0040014]; rhythmic synaptic transmission [GO:0060024] comp146000_c0_seq1,236,34.7458,0.14311851,3,28,,1.00E-09,B0X0K1,Transcription factor Ken 2,Transcription factor Ken 2,GO:0003677; GO:0045497; GO:0030540; GO:0045496; GO:0030539; GO:0046872; GO:0046426; GO:0005634; GO:0003700; GO:0006351,"DNA binding; female analia development; female genitalia development; male analia development; male genitalia development; metal ion binding; negative regulation of JAK-STAT cascade; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;,,,,,,,,,KEN2_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens),"female analia development [GO:0045497]; female genitalia development [GO:0030540]; male analia development [GO:0045496]; male genitalia development [GO:0030539]; negative regulation of JAK-STAT cascade [GO:0046426]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146021_c0_seq1,763,42.595,0.29133668,29,43,,2.00E-11,Q8BL99,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,5.00E-31,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp146024_c0_seq1,201,46.2687,0.09474906,4,18,,6.00E-10,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp146030_c0_seq1,217,58.0645,0.82473378,0,22,,2.00E-10,P49215,40S ribosomal protein S17,40S ribosomal protein S17,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00833;,,,,,,,,,RS17_SOLLC,Solanum lycopersicum (Tomato) (Lycopersicon esculentum),ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] comp146033_c0_seq1,360,42.7778,0.49922598,14,20,,6.00E-15,A6H8I2,Small G protein signaling modulator 3 homolog (RUN and TBC1 domain-containing protein 3),Small G protein signaling modulator 3 homolog (RUN and TBC1 domain-containing protein 3),GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF02759;PF00018;,2.00E-38,CHOYP_LOC100116018.1.1,,,,,,,SGSM3_XENLA,Xenopus laevis (African clawed frog), comp146036_c0_seq1,476,42.8571,0.59608069,9,35,,7.00E-09,Q63504,Nuclear receptor subfamily 1 group D member 2 (EAR4) (Rev-erb-beta),Nuclear receptor subfamily 1 group D member 2 (EAR4) (Rev-erb-beta),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,9.00E-26,CHOYP_DGRI_GH14972.1.1,,,,,,,NR1D2_RAT,Rattus norvegicus (Rat),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp146040_c0_seq1,224,37.0536,0.66490687,0,14,,7.00E-12,A6NGD5,Zinc finger and SCAN domain-containing protein 5C,Putative zinc finger and SCAN domain-containing protein 5C (Zinc finger and SCAN domain-containing protein 5C pseudogene),GO:0046872; GO:0003676; GO:0005634; GO:0000981,metal ion binding; nucleic acid binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF02023;PF00096;,,,,,,,,,ZSA5C_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp146061_c0_seq1,209,39.7129,0.24390802,0,17,,9.00E-11,Q9QZ48,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein),GO:0003677; GO:0030154; GO:0035035; GO:0046872; GO:0007275; GO:0045892; GO:0005634; GO:0045670; GO:0003700; GO:0006351,"DNA binding; cell differentiation; histone acetyltransferase binding; metal ion binding; multicellular organismal development; negative regulation of transcription, DNA-dependent; nucleus; regulation of osteoclast differentiation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146074_c0_seq1,305,45.9016,0.81201118,1,32,,2.00E-13,A2AGA4,"Rhomboid-related protein 2 (RRP2) (EC 3.4.21.105) [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)]","Rhomboid-related protein 2 (RRP2) (EC 3.4.21.105) [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)]",GO:0016021; GO:0005886; GO:0006508; GO:0004252,integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity,PF01694;,,,,,,,,,RHBL2_MOUSE,Mus musculus (Mouse),protein processing [GO:0016485] comp146075_c0_seq1,250,46.4,0.60574122,6,20,,4.00E-08,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp146078_c0_seq1,256,40.625,0.57027497,4,23,,,,,,,,,6.00E-18,CHOYP_PZRN4.1.1,,,,,,,,, comp146090_c0_seq1,311,42.1222,0.39157031,0,15,,3.00E-15,Q3UDW8,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0016746,"heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; transferase activity, transferring acyl groups",PF07786;,5.00E-14,CHOYP_HGSNAT.1.2,,,,,,,HGNAT_MOUSE,Mus musculus (Mouse),lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp146105_c0_seq1,268,33.5821,0.96863489,2,19,,3.00E-06,B1A193,Ras association domain-containing protein 10,Ras association domain-containing protein 10,GO:0005829; GO:0005815; GO:0007165; GO:0000922,cytosol; microtubule organizing center; signal transduction; spindle pole,,,,,,,,,,RASFA_XENLA,Xenopus laevis (African clawed frog),signal transduction [GO:0007165] comp146115_c0_seq1,273,37.7289,0.42219365,6,21,,4.00E-37,Q9VCU9,Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-),Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-),GO:0005524; GO:0016442; GO:0016443; GO:0005737; GO:0048813; GO:0003725; GO:0033227; GO:0042078; GO:0030727; GO:0007294; GO:0004386; GO:0046872; GO:0045448; GO:0007279; GO:0070883; GO:0031054; GO:0030422; GO:0007367; GO:0035087; GO:0003727,"ATP binding; RISC complex; bidentate ribonuclease III activity; cytoplasm; dendrite morphogenesis; double-stranded RNA binding; dsRNA transport; germ-line stem cell division; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; helicase activity; metal ion binding; mitotic cell cycle, embryonic; pole cell formation; pre-miRNA binding; pre-miRNA processing; production of siRNA involved in RNA interference; segment polarity determination; siRNA loading onto RISC involved in RNA interference; single-stranded RNA binding",PF03368;PF00271;PF02170;PF00636;,6.00E-63,CHOYP_DICER.1.3,,,,,,,DCR1_DROME,Drosophila melanogaster (Fruit fly),"apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line stem cell division [GO:0042078]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; response to starvation [GO:0042594]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]" comp146116_c0_seq1,315,46.9841,0.81160238,4,28,,7.00E-42,P61969,LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4),LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4),GO:0001158; GO:0031333; GO:0001843; GO:0045944; GO:0050865; GO:0042659; GO:0021527; GO:0021522; GO:0048538; GO:0008134; GO:0005667; GO:0006366; GO:0021514; GO:0003281; GO:0008270,enhancer sequence-specific DNA binding; negative regulation of protein complex assembly; neural tube closure; positive regulation of transcription from RNA polymerase II promoter; regulation of cell activation; regulation of cell fate specification; spinal cord association neuron differentiation; spinal cord motor neuron differentiation; thymus development; transcription factor binding; transcription factor complex; transcription from RNA polymerase II promoter; ventral spinal cord interneuron differentiation; ventricular septum development; zinc ion binding,PF00412;,,,,,,,,,LMO4_MOUSE,Mus musculus (Mouse),negative regulation of protein complex assembly [GO:0031333]; neural tube closure [GO:0001843]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell activation [GO:0050865]; regulation of cell fate specification [GO:0042659]; regulation of cell migration [GO:0030334]; spinal cord association neuron differentiation [GO:0021527]; spinal cord motor neuron differentiation [GO:0021522]; thymus development [GO:0048538]; transcription from RNA polymerase II promoter [GO:0006366]; ventral spinal cord interneuron differentiation [GO:0021514]; ventricular septum development [GO:0003281] comp146117_c0_seq1,595,49.5798,0.68663788,32,25,,1.00E-68,Q8BPN8,DmX-like protein 2 (Rabconnectin-3),DmX-like protein 2 (Rabconnectin-3),GO:0030054; GO:0030672,cell junction; synaptic vesicle membrane,PF12234;PF00400;,1.00E-89,CHOYP_AGAP_AGAP010490.1.1,,,,,,,DMXL2_MOUSE,Mus musculus (Mouse), comp146122_c0_seq1,479,37.1608,0.97068168,15,23,,3.00E-08,P02671,Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain],Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain],GO:0005938; GO:0009897; GO:0005577; GO:0030168; GO:0031093; GO:0002576; GO:0051258; GO:0051592; GO:0007165,cell cortex; external side of plasma membrane; fibrinogen complex; platelet activation; platelet alpha granule lumen; platelet degranulation; protein polymerization; response to calcium ion; signal transduction,PF08702;PF12160;PF00147;,,,,,,,,,FIBA_HUMAN,Homo sapiens (Human),"acute-phase response [GO:0006953]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein complex assembly [GO:0043623]; cellular protein metabolic process [GO:0044267]; cellular response to granulocyte colony-stimulating factor [GO:1990643]; cellular response to interleukin-6 [GO:0071354]; cellular response to organic cyclic compound [GO:0071407]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; liver regeneration [GO:0097421]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; protein complex assembly [GO:0006461]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; response to genistein [GO:0033595]; response to morphine [GO:0043278]; signal transduction [GO:0007165]" comp146123_c0_seq1,238,45.7983,0.73464412,0,37,,6.00E-16,Q8BM14,Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2),Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2),GO:0005576; GO:0016788; GO:0016042,"extracellular region; hydrolase activity, acting on ester bonds; lipid catabolic process",PF00561;,,,,,,,,,LIPK_MOUSE,Mus musculus (Mouse),lipid catabolic process [GO:0016042] comp146124_c0_seq1,511,47.9452,0.49143202,16,48,,7.00E-42,Q6ZWJ1,Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip),Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip),GO:0005509; GO:0005737; GO:0015758; GO:0008286; GO:0045111; GO:0005634; GO:0006605,calcium ion binding; cytoplasm; glucose transport; insulin receptor signaling pathway; intermediate filament cytoskeleton; nucleus; protein targeting,PF00595;PF00397;,,,,,,,,,STXB4_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178] comp146127_c0_seq1,403,46.6501,0.28361003,5,13,,3.00E-51,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,2.00E-19,CHOYP_MRP4.1.3,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp146129_c0_seq1,494,43.7247,0.59927606,11,22,,2.00E-53,Q9TRY9,Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),GO:0004565; GO:0005975; GO:0005764,beta-galactosidase activity; carbohydrate metabolic process; lysosome,PF13364;PF01301;,5.00E-23,CHOYP_BGAL.2.2,,,,,,,BGAL_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),carbohydrate metabolic process [GO:0005975] comp146132_c0_seq1,353,42.7762,0.68994175,7,19,,1.00E-53,Q14161,ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2),ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2),GO:0008060; GO:0005654; GO:0043547; GO:0032312; GO:0008277; GO:0008270,ARF GTPase activator activity; nucleoplasm; positive regulation of GTPase activity; regulation of ARF GTPase activity; regulation of G-protein coupled receptor protein signaling pathway; zinc ion binding,PF12796;PF01412;PF12205;PF16559;PF08518;,4.00E-41,CHOYP_GIT1.2.2,,,,,,,GIT2_HUMAN,Homo sapiens (Human),behavioral response to pain [GO:0048266]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp146151_c0_seq1,226,42.9204,1.062574,0,23,,4.00E-11,Q5R2I8,Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (cAPCDD1) (Protein primglo1),Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (cAPCDD1) (Protein primglo1),GO:0016055; GO:0017147; GO:0043615; GO:0001942; GO:0005887; GO:0030178,Wnt receptor signaling pathway; Wnt-protein binding; astrocyte cell migration; hair follicle development; integral to plasma membrane; negative regulation of Wnt receptor signaling pathway,PF14921;,,,,,,,,,APCD1_CHICK,Gallus gallus (Chicken),astrocyte cell migration [GO:0043615]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp146161_c0_seq1,360,40.5556,0.88481075,0,35,,1.00E-41,A4IF78,Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8),Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8),GO:0043027; GO:0005737,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm,PF05527;,3.00E-18,CHOYP_LOC100369290.1.1,3.00E-47,ruditapes2_c2637,,,,,TFIP8_BOVIN,Bos taurus (Bovine), comp146162_c0_seq1,386,43.5233,0.50988485,20,17,,7.00E-31,Q0P483,Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),GO:0015217; GO:0080122; GO:0005347; GO:0043262; GO:0015228; GO:0016021; GO:0005743; GO:0005739,ADP transmembrane transporter activity; AMP transmembrane transporter activity; ATP transmembrane transporter activity; adenosine-diphosphatase activity; coenzyme A transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; mitochondrion,PF00153;,,,,,,,,,S2542_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412] comp146164_c0_seq1,205,40.9756,0.24235871,2,13,,,,,,,,,4.00E-13,CHOYP_contig_055438,,,,,,,,, comp146175_c0_seq1,334,44.3114,0.69437216,4,24,,1.00E-09,Q8TAC1,Rieske domain-containing protein,Rieske domain-containing protein,GO:0051537; GO:0046872; GO:0016491,"2 iron, 2 sulfur cluster binding; metal ion binding; oxidoreductase activity",PF00355;,,,,,,,,,RFESD_HUMAN,Homo sapiens (Human), comp146180_c0_seq1,354,37.2881,0.9039424,11,21,,5.00E-21,Q8TBE0,Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1),Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1),GO:0003677; GO:0003682; GO:0005677; GO:0005694; GO:0031507; GO:0045892; GO:0006351,"DNA binding; chromatin binding; chromatin silencing complex; chromosome; heterochromatin assembly; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;,,,,,,,,,BAHD1_HUMAN,Homo sapiens (Human),"chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp146191_c0_seq1,293,46.7577,0.31343649,1,27,,9.00E-18,P11442,Clathrin heavy chain 1,Clathrin heavy chain 1,GO:0007030; GO:0030315; GO:0030506; GO:0030118; GO:0030132; GO:0030130; GO:0030669; GO:0031072; GO:0006886; GO:0042470; GO:0007067; GO:0042277; GO:0006898; GO:0005819; GO:0005198,Golgi organization; T-tubule; ankyrin binding; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin-coated endocytic vesicle membrane; heat shock protein binding; intracellular protein transport; melanosome; mitosis; peptide binding; receptor-mediated endocytosis; spindle; structural molecule activity,PF00637;PF09268;PF01394;,4.00E-27,CHOYP_CLTC.1.1,,,,,,,CLH_RAT,Rattus norvegicus (Rat),Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic nuclear division [GO:0007067]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; receptor-mediated endocytosis [GO:0006898] comp146228_c0_seq1,232,37.931,1.20353476,0,28,,1.00E-09,Q7LFX5,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0030206; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; chondroitin sulfate biosynthetic process; hexose biosynthetic process; integral to membrane,,,,,,,,,,CHSTF_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319] comp146243_c0_seq1,279,69.1756,1.23362857,2,28,,,,,,,,,3.00E-16,CHOYP_LOC101165464.1.1,,,,,,,,, comp146244_c0_seq1,447,42.953,0.39734123,14,20,,,,,,,,,3.00E-25,CHOYP_BRAFLDRAFT_75632.1.1,,,,,,,,, comp146246_c0_seq1,221,43.8914,1.22811025,0,21,,4.00E-11,Q9Z2W9,"Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3)","Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3)",GO:0004971; GO:0032281; GO:0030054; GO:0005234; GO:0045211,alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; cell junction; extracellular-glutamate-gated ion channel activity; postsynaptic membrane,PF01094;PF00060;PF10613;,,,,,,,,,GRIA3_MOUSE,Mus musculus (Mouse),response to fungicide [GO:0060992] comp146252_c0_seq1,257,42.0233,0.35403623,8,14,,2.00E-24,Q9NY47,Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2],Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2],GO:0006112; GO:0046872; GO:0048747; GO:0007528; GO:0005886; GO:0046622; GO:0050796; GO:0040014; GO:0060024; GO:0044281; GO:0005245; GO:0005891,energy reserve metabolic process; metal ion binding; muscle fiber development; neuromuscular junction development; plasma membrane; positive regulation of organ growth; regulation of insulin secretion; regulation of multicellular organism growth; rhythmic synaptic transmission; small molecule metabolic process; voltage-gated calcium channel activity; voltage-gated calcium channel complex,PF08473;PF00092;PF08399;,,,,,,,,,CA2D2_HUMAN,Homo sapiens (Human),cardiac conduction [GO:0061337]; muscle fiber development [GO:0048747]; neuromuscular junction development [GO:0007528]; positive regulation of organ growth [GO:0046622]; regulation of insulin secretion [GO:0050796]; regulation of multicellular organism growth [GO:0040014]; rhythmic synaptic transmission [GO:0060024] comp146269_c0_seq1,312,45.8333,0.50791597,0,42,,6.00E-36,Q03206,Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1),Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1),GO:0005525; GO:0003924; GO:0006915; GO:0048846; GO:0031103; GO:0010171; GO:0009986; GO:0031410; GO:0005829; GO:0033563; GO:0043652; GO:0016021; GO:0009898; GO:0008045; GO:0002119; GO:0001764; GO:0030334; GO:0050764; GO:0007264,GTP binding; GTPase activity; apoptotic process; axon extension involved in axon guidance; axon regeneration; body morphogenesis; cell surface; cytoplasmic vesicle; cytosol; dorsal/ventral axon guidance; engulfment of apoptotic cell; integral to membrane; internal side of plasma membrane; motor neuron axon guidance; nematode larval development; neuron migration; regulation of cell migration; regulation of phagocytosis; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAC1_CAEEL,Caenorhabditis elegans,"apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; engulfment of apoptotic cell [GO:0043652]; gastrulation [GO:0007369]; motor neuron axon guidance [GO:0008045]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264]" comp146275_c0_seq1,406,57.1429,0.75820132,0,28,,9.00E-12,Q45011,Basic membrane protein B,Basic membrane protein B,GO:0005886,plasma membrane,PF02608;,,,,,,,,,BMPB_BORBU,Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680), comp146281_c0_seq1,440,41.3636,0.21512306,2,45,,1.00E-11,O18023,Ig-like and fibronectin type-III domain-containing protein C25G4.10,Ig-like and fibronectin type-III domain-containing protein 2,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF01682;PF00041;PF00047;PF14625;,,,,,,,,,YPG43_CAEEL,Caenorhabditis elegans,cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] comp146290_c0_seq1,224,45.5357,0.98962388,1,15,,1.00E-09,G2TRN6,Putative aryl-alcohol dehydrogenase C750.01 (EC 1.1.1.-),Putative aryl-alcohol dehydrogenase C750.01 (EC 1.1.1.-),GO:0016491,oxidoreductase activity,PF00248;,,,4.00E-11,ruditapes_c10026,,,,,YLZ1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp146292_c0_seq1,421,45.3682,1.16062261,9,34,,2.00E-34,D2KQB0,Hematopoietically-expressed homeobox protein HHEX homolog (AmHEX) (Homeobox protein HEX) (HEX homeodomain transcription factor),Hematopoietically-expressed homeobox protein HHEX homolog (AmHEX) (Homeobox protein HEX) (HEX homeodomain transcription factor),GO:0007275; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;,2.00E-21,CHOYP_HHEX.2.2,,,,,,,HHEX_ASTMI,Patiria miniata (Bat star) (Asterina miniata),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146295_c0_seq1,216,37.5,0.13248147,4,14,,5.00E-09,Q9SZR9,ABC transporter G family member 9 (ABC transporter ABCG.9) (AtABCG9) (Probable white-brown complex homolog protein 9) (AtWBC9),ABC transporter G family member 9 (ABC transporter ABCG.9) (AtABCG9) (Probable white-brown complex homolog protein 9) (AtWBC9),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF01061;PF00005;,,,,,,,,,AB9G_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp146296_c0_seq1,422,34.8341,0.25079192,2,26,,,,,,,,,,,6.00E-12,ruditapes_c17037,,,,,,, comp146300_c0_seq1,291,50.1718,0.35545155,12,23,,7.00E-09,Q803R5,Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),GO:0006370; GO:0097309; GO:0004483; GO:0003676; GO:0005634,7-methylguanosine mRNA capping; cap1 mRNA methylation; mRNA (nucleoside-2'-O-)-methyltransferase activity; nucleic acid binding; nucleus,PF01728;PF01585;PF00397;,2.00E-12,CHOYP_MTR1.1.1,,,,,,,MTR1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009] comp146303_c0_seq1,300,41.6667,0.93819224,4,13,,2.00E-08,Q7RTS6,Otopetrin-2,Otopetrin-2,GO:0016021,integral to membrane,PF03189;,,,,,,,,,OTOP2_HUMAN,Homo sapiens (Human), comp146316_c0_seq1,485,40.2062,1.03032026,10,33,,,,,,,,,3.00E-13,CHOYP_contig_032382,,,,,,,,, comp146334_c0_seq1,905,41.8785,0.58096424,37,29,,5.00E-19,Q9Y2H8,Zinc finger protein 510,Zinc finger protein 510,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN510_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146345_c0_seq1,332,43.3735,1.0624224,8,20,,4.00E-28,Q9Y5W8,Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1),Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1),GO:0007154; GO:0005769; GO:0031901; GO:0006886; GO:0035091; GO:0043547; GO:0038032,cell communication; early endosome; early endosome membrane; intracellular protein transport; phosphatidylinositol binding; positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway,PF08628;PF00787;PF02194;PF00615;,2.00E-20,CHOYP_BRAFLDRAFT_67769.1.1,,,,,,,SNX13_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547] comp146361_c0_seq1,233,45.4936,0.99966242,14,20,,6.00E-08,Q8TAV3,Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1),Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705; GO:0044281; GO:0006805,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; small molecule metabolic process; xenobiotic metabolic process",PF00067;,,,,,,,,,CP2W1_HUMAN,Homo sapiens (Human),aflatoxin B1 metabolic process [GO:0043390]; xenobiotic metabolic process [GO:0006805] comp146364_c0_seq1,262,45.4198,0.41120049,2,20,,2.00E-10,Q4KL91,Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4),Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4),GO:0006865; GO:0016021; GO:0015293,amino acid transport; integral to membrane; symporter activity,PF01490;,,,,,,,,,S36A4_XENLA,Xenopus laevis (African clawed frog),amino acid transport [GO:0006865] comp146377_c0_seq1,230,57.3913,1.16776105,0,22,,9.00E-32,P72235,Trehalose synthase (EC 5.4.99.16) (Maltose alpha-D-glucosyltransferase),Trehalose synthase (EC 5.4.99.16) (Maltose alpha-D-glucosyltransferase),GO:0005975; GO:0047471; GO:0046872,carbohydrate metabolic process; maltose alpha-D-glucosyltransferase activity; metal ion binding,PF00128;PF16657;,,,,,,,,,TRES_PIMSR,Pimelobacter sp. (strain R48),carbohydrate metabolic process [GO:0005975] comp146383_c0_seq1,419,41.0501,0.51555122,12,30,,2.00E-51,Q14644,Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein),Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein),GO:0005099; GO:0015278; GO:0005737; GO:0035556; GO:0031235; GO:0046872; GO:0046580; GO:0005543; GO:0007165,Ras GTPase activator activity; calcium-release channel activity; cytoplasm; intracellular signal transduction; intrinsic to internal side of plasma membrane; metal ion binding; negative regulation of Ras protein signal transduction; phospholipid binding; signal transduction,PF00779;PF00168;PF00169;PF00616;,,,,,,,,,RASA3_HUMAN,Homo sapiens (Human),MAPK cascade [GO:0000165]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165] comp146391_c0_seq1,373,37.5335,0.460311,16,22,,1.00E-07,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp146403_c0_seq1,201,37.3134,0.74816667,0,19,,5.00E-13,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp146404_c0_seq1,280,39.6429,1.18605409,2,19,,9.00E-06,P42664,Embryonic protein UVS.2 (EC 3.4.24.-),Embryonic protein UVS.2 (EC 3.4.24.-),GO:0004222; GO:0006508; GO:0008270,metalloendopeptidase activity; proteolysis; zinc ion binding,PF01400;PF00431;,,,,,,,,,UVS2_XENLA,Xenopus laevis (African clawed frog), comp146406_c0_seq1,946,43.4461,0.67293647,21,36,,1.00E-18,Q8BGY4,Kelch-like protein 26,Kelch-like protein 26,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH26_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp146407_c0_seq1,206,40.2913,0.61171654,3,18,,2.00E-31,Q4ZIN3,Membralin (Transmembrane protein 259),Membralin (Transmembrane protein 259),GO:0005737; GO:0016021,cytoplasm; integral to membrane,PF09746;,1.00E-19,CHOYP_LOC100712483.1.1,,,,,,,MBRL_HUMAN,Homo sapiens (Human),negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976] comp146415_c0_seq1,221,45.7014,0.78539344,0,23,,2.00E-27,Q704E8,"ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)","ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)",GO:0005524; GO:0042626; GO:0006879; GO:0016021; GO:0005743,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cellular iron ion homeostasis; integral to membrane; mitochondrial inner membrane",PF00664;PF00005;,,,,,,,,,ABCB7_RAT,Rattus norvegicus (Rat),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp146428_c0_seq1,277,44.0433,0.65470385,0,31,,6.00E-19,Q9XT77,Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6),Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00474;,1.00E-14,CHOYP_LOC582008.3.3,,,,,,,SC5A6_RABIT,Oryctolagus cuniculus (Rabbit),sodium ion transport [GO:0006814] comp146444_c0_seq1,284,39.0845,1.0278816,2,23,,1.00E-11,A1YPR0,Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C),Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C),GO:0046872; GO:0003676,metal ion binding; nucleic acid binding,PF00651;,,,,,,,,,ZBT7C_HUMAN,Homo sapiens (Human),positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025] comp146449_c0_seq1,424,37.5,1.02657576,0,48,,5.00E-16,P14600,Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1),Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1),GO:0002526; GO:0002118; GO:0003051; GO:0008306; GO:0048266; GO:0044297; GO:0009986; GO:0005737; GO:0030425; GO:0042755; GO:0007204; GO:0016021; GO:0007616; GO:0035106; GO:0005886; GO:0045760; GO:0045777; GO:0010634; GO:0050679; GO:0046887; GO:0002687; GO:0050671; GO:0045778; GO:0035815; GO:0046878; GO:0051496; GO:0032230; GO:0032224; GO:0070474; GO:0043117; GO:0045907; GO:0014910; GO:0048660; GO:0010996; GO:0032355; GO:0045471; GO:0009408; GO:0043278; GO:0035094; GO:0010193; GO:0032570; GO:0019233; GO:0060083; GO:0042713; GO:0016496,"acute inflammatory response; aggressive behavior; angiotensin-mediated drinking behavior; associative learning; behavioral response to pain; cell body; cell surface; cytoplasm; dendrite; eating behavior; elevation of cytosolic calcium ion concentration; integral to membrane; long-term memory; operant conditioning; plasma membrane; positive regulation of action potential; positive regulation of blood pressure; positive regulation of epithelial cell migration; positive regulation of epithelial cell proliferation; positive regulation of hormone secretion; positive regulation of leukocyte migration; positive regulation of lymphocyte proliferation; positive regulation of ossification; positive regulation of renal sodium excretion; positive regulation of saliva secretion; positive regulation of stress fiber assembly; positive regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, cholinergic; positive regulation of uterine smooth muscle contraction; positive regulation of vascular permeability; positive regulation of vasoconstriction; regulation of smooth muscle cell migration; regulation of smooth muscle cell proliferation; response to auditory stimulus; response to estradiol stimulus; response to ethanol; response to heat; response to morphine; response to nicotine; response to ozone; response to progesterone stimulus; sensory perception of pain; smooth muscle contraction involved in micturition; sperm ejaculation; substance P receptor activity",PF00001;,1.00E-11,CHOYP_LOC100372307.1.1,,,,,,,NK1R_RAT,Rattus norvegicus (Rat),"acute inflammatory response [GO:0002526]; aggressive behavior [GO:0002118]; angiotensin-mediated drinking behavior [GO:0003051]; associative learning [GO:0008306]; behavioral response to pain [GO:0048266]; cell surface receptor signaling pathway [GO:0007166]; eating behavior [GO:0042755]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; neuropeptide signaling pathway [GO:0007218]; operant conditioning [GO:0035106]; positive regulation of action potential [GO:0045760]; positive regulation of blood pressure [GO:0045777]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of hormone secretion [GO:0046887]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of ossification [GO:0045778]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of saliva secretion [GO:0046878]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; positive regulation of vasoconstriction [GO:0045907]; regulation of blood pressure [GO:0008217]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell proliferation [GO:0048660]; response to auditory stimulus [GO:0010996]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to morphine [GO:0043278]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to ozone [GO:0010193]; response to progesterone [GO:0032570]; sensory perception of pain [GO:0019233]; smooth muscle contraction involved in micturition [GO:0060083]; sperm ejaculation [GO:0042713]" comp146452_c0_seq1,336,45.2381,0.83431331,0,30,,4.00E-09,Q8NFZ4,Neuroligin-2,Neuroligin-2,GO:0050839; GO:0030054; GO:0009986; GO:0045217; GO:0097116; GO:0060077; GO:0005887; GO:0035641; GO:0042043; GO:0050885; GO:0007158; GO:2000463; GO:0097151; GO:0051965; GO:0032230; GO:0051968; GO:0097119; GO:0045211; GO:0097104; GO:0042734; GO:0097105; GO:0035418; GO:0004872; GO:2000311; GO:0002087; GO:0019233; GO:0072553,"cell adhesion molecule binding; cell junction; cell surface; cell-cell junction maintenance; gephyrin clustering; inhibitory synapse; integral to plasma membrane; locomotory exploration behavior; neurexin family protein binding; neuromuscular process controlling balance; neuron cell-cell adhesion; positive regulation of excitatory postsynaptic membrane potential; positive regulation of inhibitory postsynaptic membrane potential; positive regulation of synapse assembly; positive regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, glutamatergic; postsynaptic density protein 95 clustering; postsynaptic membrane; postsynaptic membrane assembly; presynaptic membrane; presynaptic membrane assembly; protein localization to synapse; receptor activity; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; regulation of respiratory gaseous exchange by neurological system process; sensory perception of pain; terminal button organization",PF00135;,,,,,,,,,NLGN2_HUMAN,Homo sapiens (Human),"cell-cell junction maintenance [GO:0045217]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; locomotory exploration behavior [GO:0035641]; modulation of synaptic transmission [GO:0050804]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of synaptic vesicle clustering [GO:2000809]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization to synapse [GO:0035418]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; sensory perception of pain [GO:0019233]; single organismal cell-cell adhesion [GO:0016337]; synapse assembly [GO:0007416]; synapse organization [GO:0050808]; terminal button organization [GO:0072553]" comp146453_c0_seq1,300,40,0.91998799,4,25,,1.00E-19,Q9GUM2,"Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)","Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)",GO:0033207; GO:0075015; GO:0016021; GO:0046872; GO:0045747; GO:0006486; GO:0009636,"beta-1,4-N-acetylgalactosaminyltransferase activity; formation of infection structure on or near host; integral to membrane; metal ion binding; positive regulation of Notch signaling pathway; protein glycosylation; response to toxic substance",PF02709;PF13733;,,,,,,,,,BRE4_CAEEL,Caenorhabditis elegans,formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636] comp146457_c0_seq1,232,50.8621,0.54313363,7,11,,1.00E-30,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-42,CHOYP_DNAH5.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp146459_c0_seq1,214,54.2056,0.77062615,0,27,,2.00E-28,A1W4H2,Heat-inducible transcription repressor HrcA,Heat-inducible transcription repressor HrcA,GO:0003677; GO:0006355; GO:0006950; GO:0006351,"DNA binding; regulation of transcription, DNA-dependent; response to stress; transcription, DNA-dependent",PF01628;PF03444;,,,,,,,,,HRCA_ACISJ,Acidovorax sp. (strain JS42),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp146474_c0_seq1,410,43.6585,0.37344459,14,18,,2.00E-29,Q8BMC3,SHC-transforming protein 2 (Protein Sck) (Protein Sli) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2),SHC-transforming protein 2 (Protein Sck) (Protein Sli) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2),GO:0035556,intracellular signal transduction,PF00640;PF00017;,,,,,,,,,SHC2_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; intracellular signal transduction [GO:0035556]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp146501_c0_seq1,269,44.9814,0.23116758,4,14,,4.00E-15,Q9Y5Q9,General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),GO:0042791; GO:0003677; GO:0005654; GO:0042797; GO:0000127,5S class rRNA transcription from RNA polymerase III type 1 promoter; DNA binding; nucleoplasm; tRNA transcription from RNA polymerase III promoter; transcription factor TFIIIC complex,PF13181;,,,,,,,,,TF3C3_HUMAN,Homo sapiens (Human),"5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]" comp146510_c0_seq1,209,35.8852,0.14936331,9,9,,2.00E-14,Q28EW0,Transmembrane protein 87A,Transmembrane protein 87A,GO:0016021,integral to membrane,PF06814;,,,,,,,,,TM87A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp146515_c0_seq1,234,44.4444,0.08851386,5,14,,2.00E-28,Q07889,Son of sevenless homolog 1 (SOS-1),Son of sevenless homolog 1 (SOS-1),GO:0003677; GO:0038095; GO:0007265; GO:0005100; GO:0005089; GO:0097190; GO:0007411; GO:0005829; GO:0007173; GO:0008543; GO:0045087; GO:0008286; GO:0050900; GO:0048011; GO:0005543; GO:0005886; GO:0030168; GO:0043065,DNA binding; Fc-epsilon receptor signaling pathway; Ras protein signal transduction; Rho GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; axon guidance; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; insulin receptor signaling pathway; leukocyte migration; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; platelet activation; positive regulation of apoptotic process,PF00125;PF00169;PF00617;PF00618;PF00621;,5.00E-44,CHOYP_SOS1.1.1,,,,,,,SOS1_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296] comp146520_c0_seq1,235,48.0851,0.29760942,3,23,,4.00E-27,Q90XC2,Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8),Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8),GO:0005524; GO:0051301; GO:0005737; GO:0001947; GO:0046872; GO:0007067; GO:0072372; GO:0072116; GO:0004674; GO:0061326,ATP binding; cell division; cytoplasm; heart looping; metal ion binding; mitosis; primary cilium; pronephros formation; protein serine/threonine kinase activity; renal tubule development,PF00069;PF00415;,5.00E-31,CHOYP_LOC100375651.1.1,,,,,,,NEK8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; mitotic nuclear division [GO:0007067]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326] comp146533_c0_seq1,683,40.7028,0.78375168,12,36,,3.00E-13,P34595,Uncharacterized protein ZC262.3,Immunoglobulin domain and leucine-rich repeat-containing protein 2,GO:0016021,integral to membrane,,,,,,,,,,YOD3_CAEEL,Caenorhabditis elegans,mitochondrial translation [GO:0032543] comp146535_c0_seq1,231,59.7403,1.08321215,2,20,,2.00E-13,P44299,Uncharacterized protein HI_1731,Uncharacterized protein HI_1731,GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF02682;,,,,,,,,,Y1731_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp146537_c0_seq1,325,42.4615,0.21298111,3,25,,3.00E-26,Q8BKD6,E3 ubiquitin-protein ligase RNF144B (EC 6.3.2.-) (IBR domain-containing protein 2) (RING finger protein 144B),E3 ubiquitin-protein ligase RNF144B (EC 6.3.2.-) (IBR domain-containing protein 2) (RING finger protein 144B),GO:0006915; GO:0016021; GO:0031966; GO:0042787; GO:0004842; GO:0008270,apoptotic process; integral to membrane; mitochondrial membrane; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF01485;,9.00E-30,CHOYP_BRAFLDRAFT_125022.1.1,,,,,,,R144B_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp146548_c0_seq1,627,42.9027,0.49095501,10,28,,4.00E-34,Q8CIV2,Membralin (Transmembrane protein 259),Membralin (Transmembrane protein 259),GO:0016021,integral to membrane,PF09746;,2.00E-35,CHOYP_LOC100712483.1.1,,,,,,,MBRL_MOUSE,Mus musculus (Mouse),negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976] comp146557_c0_seq1,242,42.1488,0.95784056,0,27,,5.00E-08,Q8JFN7,Neuronal acetylcholine receptor subunit alpha-9-I (Nicotinic acetylcholine receptor subunit alpha-9-I) (NACHR alpha-9-I),Neuronal acetylcholine receptor subunit alpha-9-I (Nicotinic acetylcholine receptor subunit alpha-9-I) (NACHR alpha-9-I),GO:0004889; GO:0030054; GO:0016021; GO:0045211,acetylcholine-activated cation-selective channel activity; cell junction; integral to membrane; postsynaptic membrane,PF02931;PF02932;,,,,,,,,,ACH91_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri), comp146559_c0_seq1,286,40.2098,0.69450335,1,28,,1.00E-17,P08043,Zinc finger protein 2 (Zfp-2) (Protein mKR2),Zinc finger protein 2 (Zfp-2) (Protein mKR2),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZFP2_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146562_c0_seq1,211,43.6019,1.23979393,4,14,,1.00E-19,A7XYI6,Sine oculis-binding protein homolog (Jackson circler protein 1),Sine oculis-binding protein homolog (Jackson circler protein 1),GO:0032184; GO:0042472; GO:0007626; GO:0046872; GO:0007605,SUMO polymer binding; inner ear morphogenesis; locomotory behavior; metal ion binding; sensory perception of sound,PF15279;,4.00E-38,CHOYP_SOBP.1.1,,,,,,,SOBP_RAT,Rattus norvegicus (Rat),cochlea development [GO:0090102]; cognition [GO:0050890]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp146568_c0_seq1,407,42.7518,0.32692505,16,14,,7.00E-63,Q9NRW7,Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45),Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45),GO:0005794; GO:0000139; GO:0007596; GO:0010008; GO:0016021; GO:0006886; GO:0006904,Golgi apparatus; Golgi membrane; blood coagulation; endosome membrane; integral to membrane; intracellular protein transport; vesicle docking involved in exocytosis,PF00995;,9.00E-63,CHOYP_VPS45.1.1,,,,,,,VPS45_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; intracellular protein transport [GO:0006886]; vesicle docking involved in exocytosis [GO:0006904] comp146569_c0_seq1,202,44.5545,0.70209231,0,18,,2.00E-18,P48056,Sodium- and chloride-dependent betaine transporter (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12),Sodium- and chloride-dependent betaine transporter (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12),GO:0071474; GO:0009992; GO:0005332; GO:0016021; GO:0005887; GO:0006836; GO:0005328; GO:0010033,cellular hyperosmotic response; cellular water homeostasis; gamma-aminobutyric acid:sodium symporter activity; integral to membrane; integral to plasma membrane; neurotransmitter transport; neurotransmitter:sodium symporter activity; response to organic substance,PF00209;,9.00E-15,CHOYP_SC6A5.6.7,,,,,,,S6A12_RAT,Rattus norvegicus (Rat),cellular hyperosmotic response [GO:0071474]; cellular water homeostasis [GO:0009992]; chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836]; response to organic substance [GO:0010033] comp146571_c0_seq1,414,44.686,0.43684465,13,27,,2.00E-07,Q0P4X6,Zinc finger and BTB domain-containing protein 44,Zinc finger and BTB domain-containing protein 44,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT44_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146575_c0_seq1,550,40.7273,0.43925528,11,27,,8.00E-52,Q8VII6,Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92),Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92),GO:0016021; GO:0006810,integral to membrane; transport,PF04515;,1.00E-62,CHOYP_BRAFLDRAFT_130395.1.1,,,,,,,CTL1_RAT,Rattus norvegicus (Rat),transport [GO:0006810] comp146581_c0_seq1,345,43.4783,0.72842717,7,24,,9.00E-33,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,7.00E-19,CHOYP_RN213.9.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp146590_c0_seq1,347,46.6859,0.56484806,10,20,,1.00E-51,Q33DR2,Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1),Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1),GO:0008299; GO:0046872; GO:0005739; GO:0046982; GO:0051290; GO:0000010; GO:0006744,isoprenoid biosynthetic process; metal ion binding; mitochondrion; protein heterodimerization activity; protein heterotetramerization; trans-hexaprenyltranstransferase activity; ubiquinone biosynthetic process,PF00348;,,,,,,,,,DPS1_MOUSE,Mus musculus (Mouse),isoprenoid biosynthetic process [GO:0008299]; protein heterotetramerization [GO:0051290]; ubiquinone biosynthetic process [GO:0006744] comp146593_c0_seq1,276,40.942,0.52396653,5,20,,1.00E-14,Q9NYP3,Protein downstream neighbor of Son (B17),Protein downstream neighbor of Son (B17),GO:0007275; GO:0005634,multicellular organismal development; nucleus,,,,,,,,,,DONS_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp146598_c0_seq1,366,45.082,0.48674103,1,37,,7.00E-49,P79457,Histone demethylase UTY (EC 1.14.11.-) (Male-specific histocompatibility antigen H-YDB) (Ubiquitously transcribed TPR protein on the Y chromosome) (Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein),Histone demethylase UTY (EC 1.14.11.-) (Male-specific histocompatibility antigen H-YDB) (Ubiquitously transcribed TPR protein on the Y chromosome) (Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein),GO:0000978; GO:0060070; GO:0086003; GO:0045184; GO:0007507; GO:0051864; GO:0001701; GO:0046872; GO:0005634; GO:0031935,RNA polymerase II core promoter proximal region sequence-specific DNA binding; canonical Wnt receptor signaling pathway; cardiac muscle cell contraction; establishment of protein localization; heart development; histone demethylase activity (H3-K36 specific); in utero embryonic development; metal ion binding; nucleus; regulation of chromatin silencing,PF02373;PF13181;,1.00E-41,CHOYP_LOC100883412.1.1,,,,,,,UTY_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; cardiac muscle cell contraction [GO:0086003]; embryonic organ development [GO:0048568]; establishment of protein localization [GO:0045184]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; regulation of chromatin silencing [GO:0031935]; regulation of gene expression [GO:0010468] comp146603_c0_seq1,351,43.0199,0.68434631,7,17,,2.00E-34,Q1PRL4,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:0021915; GO:2000637; GO:0051865; GO:0060964; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; neural tube development; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of gene silencing by miRNA; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,4.00E-16,CHOYP_LOC100367035.1.1,,,,,,,LIN41_CHICK,Gallus gallus (Chicken),fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] comp146622_c0_seq1,265,48.6792,0.64035577,17,9,,7.00E-08,Q9ERH3,WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG),WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG),,,PF00400;,,,,,,,,,WDR7_RAT,Rattus norvegicus (Rat),hematopoietic progenitor cell differentiation [GO:0002244] comp146632_c0_seq1,235,40.4255,0.42219011,0,26,,5.00E-22,O73590,Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) (Zinc finger/apterous-related homeobox protein),Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) (Zinc finger/apterous-related homeobox protein),GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;,2.00E-36,CHOYP_LOC100877335.1.1,,,,,,,ZFHX4_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146633_c0_seq1,427,38.6417,0.82625936,3,38,,1.00E-13,P26932,"Calponin-1 (Calponin, smooth muscle)","Calponin-1 (Calponin, smooth muscle)",GO:0031032,actomyosin structure organization,PF00402;PF00307;,,,,,,,,,CNN1_CHICK,Gallus gallus (Chicken),actomyosin structure organization [GO:0031032] comp146635_c0_seq1,406,38.4236,0.33586604,10,21,,6.00E-33,Q05DH4,Protein FAM160A1,Protein FAM160A1,,,PF10257;,,,,,,,,,F16A1_HUMAN,Homo sapiens (Human), comp146645_c0_seq1,508,42.126,0.57922143,8,26,,8.00E-26,Q6NYU2,Probable helicase with zinc finger domain (EC 3.6.4.-),Probable helicase with zinc finger domain (EC 3.6.4.-),GO:0005524; GO:0004386; GO:0046872; GO:0005634; GO:0003700,ATP binding; helicase activity; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity,PF00642;,,,,,,,,,HELZ_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp146646_c0_seq1,485,40.8247,0.24918071,27,0,,9.00E-11,Q99758,ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),GO:0005524; GO:0042626; GO:0097208; GO:0097233; GO:0016021; GO:0005886; GO:0042493,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; alveolar lamellar body; alveolar lamellar body membrane; integral to membrane; plasma membrane; response to drug",PF00005;,3.00E-25,CHOYP_ABCA3.3.6,,,,,,,ABCA3_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp146650_c0_seq1,303,41.9142,0.60618806,6,14,,3.00E-34,Q92562,"Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)","Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)",GO:0000139; GO:0008219; GO:0031901; GO:0031902; GO:0007626; GO:0032288; GO:0031642; GO:0048666; GO:0043813; GO:0004438; GO:0043812; GO:0043473; GO:0010976; GO:0044281; GO:0007033,"Golgi membrane; cell death; early endosome membrane; late endosome membrane; locomotory behavior; myelin assembly; negative regulation of myelination; neuron development; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; pigmentation; positive regulation of neuron projection development; small molecule metabolic process; vacuole organization",PF02383;,,,,,,,,,FIG4_HUMAN,Homo sapiens (Human),locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] comp146659_c0_seq1,294,42.517,0.83078278,3,14,,1.00E-10,Q5F4B8,Solute carrier family 46 member 3,Solute carrier family 46 member 3,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S46A3_CHICK,Gallus gallus (Chicken),transmembrane transport [GO:0055085] comp146661_c0_seq1,256,51.5625,0.53209922,6,11,,1.00E-23,Q9WTW1,Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2),Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2),GO:0030054; GO:0030425; GO:0043198; GO:0043197; GO:0005783; GO:0014069; GO:0045211; GO:0015031,cell junction; dendrite; dendritic shaft; dendritic spine; endoplasmic reticulum; postsynaptic density; postsynaptic membrane; protein transport,PF00595;,,,,,,,,,GRIP2_RAT,Rattus norvegicus (Rat),artery smooth muscle contraction [GO:0014824]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; protein transport [GO:0015031] comp146665_c0_seq1,723,42.7386,0.55888262,31,17,,2.00E-07,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp146669_c0_seq1,336,46.131,0.96839938,1,21,,6.00E-09,P78560,Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain),GO:0006977; GO:0071260; GO:0005737; GO:0008625; GO:0005634; GO:0042981,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular response to mechanical stimulus; cytoplasm; extrinsic apoptotic signaling pathway via death domain receptors; nucleus; regulation of apoptotic process",PF00619;PF00531;,,,,,,,,,CRADD_HUMAN,Homo sapiens (Human),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]" comp14666_c0_seq1,341,46.9208,0.64947544,4,0,,3.00E-06,O43829,Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5),Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5),GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZF161_HUMAN,Homo sapiens (Human),"cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart valve development [GO:0003170]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp146695_c0_seq1,246,49.5935,1.01314225,6,12,,9.00E-10,Q63870,Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen),Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen),GO:0005604; GO:0007155; GO:0005581; GO:0004867,basement membrane; cell adhesion; collagen; serine-type endopeptidase inhibitor activity,PF01391;PF00041;PF00014;PF00092;,,,,,,,,,CO7A1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] comp146708_c0_seq1,249,42.1687,0.63776539,3,20,,1.00E-07,Q88CW6,Oxygen-dependent choline dehydrogenase (CDH) (CHD) (EC 1.1.99.1) (Betaine aldehyde dehydrogenase) (BADH) (EC 1.2.1.8),Oxygen-dependent choline dehydrogenase (CDH) (CHD) (EC 1.1.99.1) (Betaine aldehyde dehydrogenase) (BADH) (EC 1.2.1.8),GO:0008802; GO:0008812; GO:0050660; GO:0019285,betaine-aldehyde dehydrogenase activity; choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline,PF05199;PF00732;,,,,,,,,,BETA_PSEPK,Pseudomonas putida (strain KT2440),glycine betaine biosynthetic process from choline [GO:0019285] comp146713_c0_seq1,222,40.0901,0.45096972,6,15,,2.00E-13,Q7Z6J6,FERM domain-containing protein 5,FERM domain-containing protein 5,GO:0005737; GO:0005856; GO:0019898; GO:0016021,cytoplasm; cytoskeleton; extrinsic to membrane; integral to membrane,PF08736;PF09380;PF00373;PF09379;,,,,,,,,,FRMD5_HUMAN,Homo sapiens (Human), comp146732_c0_seq1,526,47.3384,0.44217276,33,6,,1.00E-67,Q9HC10,Otoferlin (Fer-1-like protein 2),Otoferlin (Fer-1-like protein 2),GO:0016323; GO:0005509; GO:0030054; GO:0005829; GO:0005789; GO:0016021; GO:0061025; GO:0007605; GO:0016079; GO:0030672,basolateral plasma membrane; calcium ion binding; cell junction; cytosol; endoplasmic reticulum membrane; integral to membrane; membrane fusion; sensory perception of sound; synaptic vesicle exocytosis; synaptic vesicle membrane,PF00168;PF08150;PF08151;PF16165;,3.00E-77,CHOYP_OTOF.1.1,,,,,,,OTOF_HUMAN,Homo sapiens (Human),cochlea development [GO:0090102]; membrane fusion [GO:0061025]; sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079] comp146742_c0_seq1,290,48.6207,0.58622776,4,20,,2.00E-34,P53349,Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1),GO:0005524; GO:0008545; GO:0004709; GO:0000186; GO:0008637; GO:0005829; GO:0003382; GO:0061029; GO:0030838; GO:0030334; GO:0007179; GO:0042060; GO:0008270,ATP binding; JUN kinase kinase activity; MAP kinase kinase kinase activity; activation of MAPKK activity; apoptotic mitochondrial changes; cytosol; epithelial cell morphogenesis; eyelid development in camera-type eye; positive regulation of actin filament polymerization; regulation of cell migration; transforming growth factor beta receptor signaling pathway; wound healing; zinc ion binding,PF00069;PF04434;,3.00E-23,CHOYP_LOC100334486.1.1,,,,,,,M3K1_MOUSE,Mus musculus (Mouse),activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060] comp146758_c0_seq1,811,40.9371,0.88453294,20,34,,2.00E-32,Q5IS76,Neuronal acetylcholine receptor subunit alpha-6,Neuronal acetylcholine receptor subunit alpha-6,GO:0015464; GO:0004889; GO:0005892; GO:0035095; GO:0030054; GO:0051899; GO:0007399; GO:0045211; GO:0014059; GO:0060084,acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; behavioral response to nicotine; cell junction; membrane depolarization; nervous system development; postsynaptic membrane; regulation of dopamine secretion; synaptic transmission involved in micturition,PF02931;PF02932;,,,,,,,,,ACHA6_PANTR,Pan troglodytes (Chimpanzee),"behavioral response to nicotine [GO:0035095]; cation transmembrane transport [GO:0098655]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; regulation of dopamine secretion [GO:0014059]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission involved in micturition [GO:0060084]" comp146769_c0_seq1,338,35.7988,0.38988265,5,21,,5.00E-13,Q8TF39,Zinc finger protein 483 (Zinc finger protein with KRAB and SCAN domains 16),Zinc finger protein 483 (Zinc finger protein with KRAB and SCAN domains 16),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZN483_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146772_c0_seq1,253,47.4308,0.21903188,1,8,,2.00E-22,Q54P79,Probable 4-coumarate--CoA ligase 3 (4CL 3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3),Probable 4-coumarate--CoA ligase 3 (4CL 3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3),GO:0016207; GO:0005524; GO:0009698,4-coumarate-CoA ligase activity; ATP binding; phenylpropanoid metabolic process,PF00501;PF13193;,,,,,,,,,4CL3_DICDI,Dictyostelium discoideum (Slime mold),phenylpropanoid metabolic process [GO:0009698] comp146776_c0_seq1,232,46.9828,0.71620183,0,21,,1.00E-18,Q49B93,Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12),Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12),GO:0016324; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; integral to membrane; sodium ion transport; symporter activity,PF00474;,1.00E-13,CHOYP_BRAFLDRAFT_213839.1.2,,,,,,,SC5AC_MOUSE,Mus musculus (Mouse),sodium ion transport [GO:0006814] comp146784_c0_seq1,213,41.3146,0.89588579,0,22,,3.00E-06,P51690,Arylsulfatase E (ASE) (EC 3.1.6.-),Arylsulfatase E (ASE) (EC 3.1.6.-),GO:0005795; GO:0004065; GO:0005788; GO:0006687; GO:0046872; GO:0043687; GO:0001501; GO:0044281,Golgi stack; arylsulfatase activity; endoplasmic reticulum lumen; glycosphingolipid metabolic process; metal ion binding; post-translational protein modification; skeletal system development; small molecule metabolic process,PF00884;,,,,,,,,,ARSE_HUMAN,Homo sapiens (Human),glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]; skeletal system development [GO:0001501] comp146792_c0_seq1,304,34.5395,0.56818797,8,18,,5.00E-12,A5PKJ4,Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24),Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24),GO:0005524; GO:0004707; GO:0000165; GO:0016605; GO:0006915; GO:0007049; GO:0030154; GO:0070301; GO:0071560; GO:0005737; GO:0005829; GO:0051534; GO:2000352; GO:2001240; GO:0034115; GO:1902176; GO:0060761; GO:0018105; GO:0051247; GO:0036003; GO:0045765,ATP binding; MAP kinase activity; MAPK cascade; PML body; apoptotic process; cell cycle; cell differentiation; cellular response to hydrogen peroxide; cellular response to transforming growth factor beta stimulus; cytoplasm; cytosol; negative regulation of NFAT protein import into nucleus; negative regulation of endothelial cell apoptotic process; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of heterotypic cell-cell adhesion; negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of response to cytokine stimulus; peptidyl-serine phosphorylation; positive regulation of protein metabolic process; positive regulation of transcription from RNA polymerase II promoter in response to stress; regulation of angiogenesis,PF00069;,1.00E-20,CHOYP_MAPK7.1.1,,,,,,,MK07_BOVIN,Bos taurus (Bovine),cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK5 cascade [GO:0070377]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of angiogenesis [GO:0045765] comp146806_c0_seq1,211,39.8104,0.36385257,1,20,,7.00E-06,Q01804,OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1),OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1),GO:0071108; GO:0006508; GO:0004843,protein K48-linked deubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,,,,,,,,,OTUD4_HUMAN,Homo sapiens (Human),protein K48-linked deubiquitination [GO:0071108] comp146813_c0_seq1,246,40.2439,0.33080904,6,11,,2.00E-18,Q61102,"ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)","ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)",GO:0005524; GO:0042626; GO:0006879; GO:0016021; GO:0005743,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cellular iron ion homeostasis; integral to membrane; mitochondrial inner membrane",PF00664;PF00005;,,,,,,,,,ABCB7_MOUSE,Mus musculus (Mouse),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp146820_c0_seq1,431,43.3875,0.395335,10,28,,5.00E-24,Q8R5G7,"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) (Dual specificity Rho- and Arf-GTPase-activating protein 1)","Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) (Dual specificity Rho- and Arf-GTPase-activating protein 1)",GO:0008060; GO:0005100; GO:0005737; GO:0005856; GO:0030027; GO:0035021; GO:0035024; GO:0030336; GO:0005547; GO:0043325; GO:0005886; GO:0043547; GO:0032312; GO:0008360; GO:0001726; GO:0007165; GO:0008270,"ARF GTPase activator activity; Rho GTPase activator activity; cytoplasm; cytoskeleton; lamellipodium; negative regulation of Rac protein signal transduction; negative regulation of Rho protein signal transduction; negative regulation of cell migration; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; plasma membrane; positive regulation of GTPase activity; regulation of ARF GTPase activity; regulation of cell shape; ruffle; signal transduction; zinc ion binding",PF01412;PF00169;PF00788;PF00620;PF07647;,,,,,,,,,ARAP3_MOUSE,Mus musculus (Mouse),negative regulation of cell migration [GO:0030336]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of cell shape [GO:0008360]; signal transduction [GO:0007165] comp146827_c0_seq1,440,39.3182,0.69538777,12,23,,5.00E-35,P35626,Beta-adrenergic receptor kinase 2 (Beta-ARK-2) (EC 2.7.11.15) (G-protein-coupled receptor kinase 3),Beta-adrenergic receptor kinase 2 (Beta-ARK-2) (EC 2.7.11.15) (G-protein-coupled receptor kinase 3),GO:0005524; GO:0004703; GO:0047696; GO:0005543; GO:0004672; GO:0031623; GO:0007165; GO:0038032,ATP binding; G-protein coupled receptor kinase activity; beta-adrenergic receptor kinase activity; phospholipid binding; protein kinase activity; receptor internalization; signal transduction; termination of G-protein coupled receptor signaling pathway,PF00169;PF00069;PF00615;,4.00E-49,CHOYP_SMP_159010.1.1.1,,,,,,,ARBK2_HUMAN,Homo sapiens (Human),receptor internalization [GO:0031623]; signal transduction [GO:0007165] comp146838_c0_seq1,220,60.9091,0.79213106,0,21,,6.00E-18,Q06879,Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-),Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-),GO:0051539; GO:0022900; GO:0005506; GO:0009399; GO:0016903; GO:0030976,"4 iron, 4 sulfur cluster binding; electron transport chain; iron ion binding; nitrogen fixation; oxidoreductase activity, acting on the aldehyde or oxo group of donors; thiamine pyrophosphate binding",PF10371;PF17147;PF01558;PF01855;PF02775;,,,,,,,,,NIFJ_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576),electron transport chain [GO:0022900]; nitrogen fixation [GO:0009399] comp146843_c0_seq1,581,35.284,0.83669023,6,50,,8.00E-11,Q87BG9,Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (HTA) (Homoserine transacetylase),Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (HTA) (Homoserine transacetylase),GO:0005737; GO:0004414; GO:0009086,cytoplasm; homoserine O-acetyltransferase activity; methionine biosynthetic process,PF00561;,,,,,,,,,METX_XYLFT,Xylella fastidiosa (strain Temecula1 / ATCC 700964),methionine biosynthetic process [GO:0009086] comp146848_c0_seq1,314,41.4013,0.15202857,5,15,,4.00E-26,Q3SZN3,"Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)","Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)",GO:0042407; GO:0002024; GO:0097009; GO:0006006; GO:0016021; GO:0006629; GO:0046872; GO:0004222; GO:0006515; GO:0005743; GO:0031966; GO:0034982; GO:0010637; GO:0006950,cristae formation; diet induced thermogenesis; energy homeostasis; glucose metabolic process; integral to membrane; lipid metabolic process; metal ion binding; metalloendopeptidase activity; misfolded or incompletely synthesized protein catabolic process; mitochondrial inner membrane; mitochondrial membrane; mitochondrial protein processing; negative regulation of mitochondrial fusion; response to stress,PF01435;,,,,,,,,,OMA1_BOVIN,Bos taurus (Bovine),cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrial protein processing [GO:0034982]; negative regulation of mitochondrial fusion [GO:0010637]; response to stress [GO:0006950] comp146853_c0_seq1,325,34.7692,0.61317195,20,15,,2.00E-14,Q8WVN8,Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2),Ubiquitin-conjugating enzyme E2 Q2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q2) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2),GO:0005524; GO:0005737; GO:0070936; GO:0004842,ATP binding; cytoplasm; protein K48-linked ubiquitination; ubiquitin-protein ligase activity,PF00179;,,,,,,,,,UB2Q2_HUMAN,Homo sapiens (Human),protein K48-linked ubiquitination [GO:0070936] comp146854_c0_seq1,240,42.5,1.51099802,0,3,,3.00E-11,P26632,Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24),Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24),GO:0003677; GO:0043010; GO:0071320; GO:0071371; GO:0005737; GO:0046872; GO:0043066; GO:0005634; GO:0048169; GO:0003700; GO:0035914; GO:0006351,"DNA binding; camera-type eye development; cellular response to cAMP; cellular response to gonadotropin stimulus; cytoplasm; metal ion binding; negative regulation of apoptotic process; nucleus; regulation of long-term neuronal synaptic plasticity; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription, DNA-dependent",PF11914;PF11928;PF00096;,,,,,,,,,EGR1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"camera-type eye development [GO:0043010]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146884_c0_seq1,322,65.8385,1.28419057,0,31,,1.00E-69,Q6A655,Deoxyribose-phosphate aldolase 2 (DERA 2) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase 2) (Phosphodeoxyriboaldolase 2) (Deoxyriboaldolase 2),Deoxyribose-phosphate aldolase 2 (DERA 2) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase 2) (Phosphodeoxyriboaldolase 2) (Deoxyriboaldolase 2),GO:0016052; GO:0005737; GO:0009264; GO:0046386; GO:0004139,carbohydrate catabolic process; cytoplasm; deoxyribonucleotide catabolic process; deoxyribose phosphate catabolic process; deoxyribose-phosphate aldolase activity,PF01791;,,,,,,,,,DEOC2_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386] comp146889_c0_seq1,600,46,0.34803992,23,33,,7.00E-56,Q80UN1,BTB/POZ domain-containing protein KCTD9,BTB/POZ domain-containing protein KCTD9,GO:0051260,protein homooligomerization,PF02214;PF11834;PF00805;,7.00E-22,CHOYP_BRAFLDRAFT_57239.1.1,,,,,,,KCTD9_MOUSE,Mus musculus (Mouse),protein homooligomerization [GO:0051260] comp146891_c0_seq1,236,37.7119,0.35946045,4,12,,4.00E-17,O75346,Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411),Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411),GO:0003677; GO:0045892; GO:0005634; GO:0006351; GO:0008270,"DNA binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZN253_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp146895_c0_seq1,362,61.0497,1.28427835,0,31,,4.00E-22,P0A962,L-asparaginase 1 (EC 3.5.1.1) (L-asparaginase I) (L-ASNase I) (L-asparagine amidohydrolase I),L-asparaginase 1 (EC 3.5.1.1) (L-asparaginase I) (L-ASNase I) (L-asparagine amidohydrolase I),GO:0004067; GO:0033345; GO:0005737; GO:0042802,asparaginase activity; asparagine catabolic process via L-aspartate; cytoplasm; identical protein binding,PF00710;,,,,,,,,,ASPG1_ECOLI,Escherichia coli (strain K12),asparagine catabolic process via L-aspartate [GO:0033345] comp146897_c0_seq1,227,37.8855,0.38688534,2,25,,1.00E-25,Q9H6Q4,Cytosolic Fe-S cluster assembly factor NARFL (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf),Cytosolic Fe-S cluster assembly factor NARFL (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf),GO:0051539; GO:0097361; GO:0016226; GO:0046872; GO:0032364; GO:0006355; GO:0001666; GO:0044281,"4 iron, 4 sulfur cluster binding; CIA complex; iron-sulfur cluster assembly; metal ion binding; oxygen homeostasis; regulation of transcription, DNA-dependent; response to hypoxia; small molecule metabolic process",PF02906;PF02256;,5.00E-31,CHOYP_BRAFLDRAFT_118961.1.1,,,,,,,NARFL_HUMAN,Homo sapiens (Human),"hematopoietic progenitor cell differentiation [GO:0002244]; iron-sulfur cluster assembly [GO:0016226]; oxygen homeostasis [GO:0032364]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]" comp146925_c0_seq1,325,44.6154,0.3751474,7,23,,,,,,,,,3.00E-11,CHOYP_LOC100877335.1.1,,,,,,,,, comp146932_c0_seq1,248,40.3226,0.80486157,10,18,,2.00E-22,P97480,Eyes absent homolog 3 (EC 3.1.3.48),Eyes absent homolog 3 (EC 3.1.3.48),GO:0003682; GO:0005737; GO:0006302; GO:0016576; GO:0046872; GO:0007275; GO:0005634; GO:0045739; GO:0004725; GO:0008138; GO:0006355; GO:0010212; GO:0005667; GO:0006351,"chromatin binding; cytoplasm; double-strand break repair; histone dephosphorylation; metal ion binding; multicellular organismal development; nucleus; positive regulation of DNA repair; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of transcription, DNA-dependent; response to ionizing radiation; transcription factor complex; transcription, DNA-dependent",,8.00E-29,CHOYP_BRAFLDRAFT_83679.2.2,,,,,,,EYA3_MOUSE,Mus musculus (Mouse),"double-strand break repair [GO:0006302]; histone dephosphorylation [GO:0016576]; multicellular organism development [GO:0007275]; positive regulation of DNA repair [GO:0045739]; protein dephosphorylation [GO:0006470]; regulation of transcription, DNA-templated [GO:0006355]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]" comp146941_c0_seq1,321,58.8785,1.18993316,2,23,,2.00E-08,P76128,"Probable D,D-dipeptide-binding periplasmic protein DdpA","Probable D,D-dipeptide-binding periplasmic protein DdpA",GO:0015833; GO:0042597; GO:0015031; GO:0005215,peptide transport; periplasmic space; protein transport; transporter activity,PF00496;,,,,,,,,,DDPA_ECOLI,Escherichia coli (strain K12),dipeptide transport [GO:0042938]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] comp146951_c0_seq1,291,45.0172,0.34369521,4,26,,,,,,,,,5.00E-33,CHOYP_LOC587502.1.1,,,,,,,,, comp146958_c0_seq1,359,35.0975,0.8333398,5,14,,1.00E-36,Q16975,Calcium-independent protein kinase C (EC 2.7.11.13) (APL II),Calcium-independent protein kinase C (EC 2.7.11.13) (APL II),GO:0005524; GO:0035556; GO:0016020; GO:0046872; GO:0004697,ATP binding; intracellular signal transduction; membrane; metal ion binding; protein kinase C activity,PF00130;PF00168;PF00069;PF00433;,5.00E-27,CHOYP_KPC2.3.3,,,,,,,KPC2_APLCA,Aplysia californica (California sea hare),intracellular signal transduction [GO:0035556] comp146959_c0_seq1,276,40.5797,0.62009129,5,16,,2.00E-08,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp146969_c0_seq1,227,70.4846,1.03898936,0,18,,3.00E-18,Q03961,Polysialic acid transport protein KpsD,Polysialic acid transport protein KpsD,GO:0016020; GO:0042597; GO:0015159,membrane; periplasmic space; polysaccharide transmembrane transporter activity,PF02563;PF10531;,,,,,,,,,KPSD1_ECOLX,Escherichia coli, comp146994_c0_seq1,432,42.1296,1.04936787,1,25,,5.00E-06,Q9Z319,"Atrial natriuretic peptide-converting enzyme (EC 3.4.21.-) (Corin) (Low density lipoprotein receptor-related protein 4) (Pro-ANP-converting enzyme) [Cleaved into: Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment]","Atrial natriuretic peptide-converting enzyme (EC 3.4.21.-) (Corin) (Low density lipoprotein receptor-related protein 4) (Pro-ANP-converting enzyme) [Cleaved into: Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment]",GO:0009986; GO:0005576; GO:0007565; GO:0005887; GO:0030182; GO:0016486; GO:0006508; GO:0035813; GO:0003050; GO:0005044; GO:0004252; GO:0070008,cell surface; extracellular region; female pregnancy; integral to plasma membrane; neuron differentiation; peptide hormone processing; proteolysis; regulation of renal sodium excretion; regulation of systemic arterial blood pressure by atrial natriuretic peptide; scavenger receptor activity; serine-type endopeptidase activity; serine-type exopeptidase activity,PF01392;PF00057;PF15494;PF00089;,,,,,,,,,CORIN_MOUSE,Mus musculus (Mouse),female pregnancy [GO:0007565]; neuron differentiation [GO:0030182]; peptide hormone processing [GO:0016486]; regulation of blood pressure [GO:0008217]; regulation of renal sodium excretion [GO:0035813]; regulation of systemic arterial blood pressure by atrial natriuretic peptide [GO:0003050] comp146_c0_seq1,210,54.7619,1.2282754,5,0,,4.00E-31,P37137,LIM/homeobox protein Lhx5 (LIM homeobox protein 5) (Homeobox protein LIM-5) (xLIM-5) (xLIM-2A),LIM/homeobox protein Lhx5 (LIM homeobox protein 5) (Homeobox protein LIM-5) (xLIM-5) (xLIM-2A),GO:0007275; GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;PF00412;,,,,,,,,,LHX5_XENLA,Xenopus laevis (African clawed frog),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp147001_c0_seq1,375,45.6,0.68325898,9,12,,3.00E-61,Q6DIP9,WASH complex subunit strumpellin,WASH complex subunit strumpellin,GO:0071203,WASH complex,PF10266;,4.00E-73,CHOYP_STRUM.1.1,,,,,,,STRUM_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein transport [GO:0015031] comp147006_c0_seq1,461,38.6117,0.59806107,3,41,,2.00E-06,Q8IZ52,Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2),Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2),GO:0032580; GO:0000139; GO:0050510; GO:0005975; GO:0030206; GO:0047238; GO:0016021; GO:0046872; GO:0016758,"Golgi cisterna membrane; Golgi membrane; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; integral to membrane; metal ion binding; transferase activity, transferring hexosyl groups",PF05679;,,,,,,,,,CHSS2_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206] comp14700_c0_seq1,241,48.9627,0.69601428,6,2,,1.00E-19,Q02934,"Endoglucanase 1 (EC 3.2.1.4) (Cellulase I) (Endo-1,4-beta-glucanase) (Endoglucanase I) (EGI)","Endoglucanase 1 (EC 3.2.1.4) (Cellulase I) (Endo-1,4-beta-glucanase) (Endoglucanase I) (EGI)",GO:0008810; GO:0030248; GO:0030245,cellulase activity; cellulose binding; cellulose catabolic process,PF00942;PF00759;,,,,,,,,,GUNI_CLOTH,Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum),cellulose catabolic process [GO:0030245] comp147025_c0_seq1,458,39.5197,0.17390838,15,24,,2.00E-21,Q96NT3,Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4),Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4),,,PF09778;,,,,,,,,,CV013_HUMAN,Homo sapiens (Human), comp147033_c0_seq1,220,69.0909,1.34011778,0,21,,2.00E-12,C5BDQ5,Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (EC 2.4.2.53) (Undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase),Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (EC 2.4.2.53) (Undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase),GO:0036108; GO:0016021; GO:0009245; GO:0009103; GO:0016780; GO:0005886; GO:0046677; GO:0016757,"4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process; integral to membrane; lipid A biosynthetic process; lipopolysaccharide biosynthetic process; phosphotransferase activity, for other substituted phosphate groups; plasma membrane; response to antibiotic; transferase activity, transferring glycosyl groups",PF00535;,,,,,,,,,ARNC_EDWI9,Edwardsiella ictaluri (strain 93-146),4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process [GO:0036108]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; response to antibiotic [GO:0046677] comp147054_c0_seq1,253,37.5494,0.56345157,3,24,,,,,,,,,2.00E-12,CHOYP_AAEL_AAEL013635.1.1,,,,,,,,, comp147066_c0_seq1,740,47.5676,0.38424961,11,32,,2.00E-78,Q5XF89,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,6.00E-81,CHOYP_PHUM_PHUM193930.1.1,,,,,,,AT133_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp147076_c0_seq1,234,45.7265,0.58334399,6,12,,3.00E-18,Q99KD5,Protein unc-45 homolog A (Unc-45A) (Stromal membrane-associated protein 1) (SMAP-1),Protein unc-45 homolog A (Unc-45A) (Stromal membrane-associated protein 1) (SMAP-1),GO:0051879; GO:0030154; GO:0061077; GO:0007517; GO:0005634; GO:0048471,Hsp90 protein binding; cell differentiation; chaperone-mediated protein folding; muscle organ development; nucleus; perinuclear region of cytoplasm,PF13181;PF11701;,1.00E-20,CHOYP_UN45B.1.1,,,,,,,UN45A_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517] comp147083_c0_seq1,349,40.9742,0.70994498,5,16,,2.00E-36,Q9NZV6,Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX),Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX),GO:0003779; GO:0030041; GO:0005737; GO:0005856; GO:0045087; GO:0070191; GO:0005634; GO:0033743; GO:0030091; GO:0008270,actin binding; actin filament polymerization; cytoplasm; cytoskeleton; innate immune response; methionine-R-sulfoxide reductase activity; nucleus; peptide-methionine (R)-S-oxide reductase activity; protein repair; zinc ion binding,PF01641;,3.00E-18,CHOYP_MSRB1.1.2,,,,,,,MSRB1_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; innate immune response [GO:0045087]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp147084_c0_seq1,417,38.3693,0.19621455,16,14,,3.00E-76,Q0GGW5,Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1 homolog) (LKB1),Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1 homolog) (LKB1),GO:0005524; GO:0007050; GO:0005829; GO:0030010; GO:0042593; GO:0072332; GO:0000287; GO:0016020; GO:0005739; GO:0030308; GO:0005634; GO:0002039; GO:0046777; GO:0030295; GO:0004674; GO:0006974; GO:0010212; GO:0001944,ATP binding; cell cycle arrest; cytosol; establishment of cell polarity; glucose homeostasis; intrinsic apoptotic signaling pathway by p53 class mediator; magnesium ion binding; membrane; mitochondrion; negative regulation of cell growth; nucleus; p53 binding; protein autophosphorylation; protein kinase activator activity; protein serine/threonine kinase activity; response to DNA damage stimulus; response to ionizing radiation; vasculature development,PF00069;,1.00E-55,CHOYP_STK11.1.1,,,,,,,STK11_CHICK,Gallus gallus (Chicken),cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212]; vasculature development [GO:0001944] comp147085_c0_seq1,265,45.283,0.5185259,13,10,,1.00E-14,O35308,Monocarboxylate transporter 3 (MCT 3) (Proton-coupled monocarboxylate transporter 3) (Solute carrier family 16 member 8),Monocarboxylate transporter 3 (MCT 3) (Proton-coupled monocarboxylate transporter 3) (Solute carrier family 16 member 8),GO:0016021; GO:0005886; GO:0015355; GO:0015293,integral to membrane; plasma membrane; secondary active monocarboxylate transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT3_MOUSE,Mus musculus (Mouse),plasma membrane lactate transport [GO:0035879] comp147094_c0_seq1,354,44.3503,0.64524639,10,10,,2.00E-40,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp147099_c0_seq1,230,46.087,0.90493164,7,9,,1.00E-10,Q9JLJ0,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Estrogen-enhanced transcript protein) (mEET) (LITAF-like protein) (NEDD4 WW domain-binding protein 3),Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Estrogen-enhanced transcript protein) (mEET) (LITAF-like protein) (NEDD4 WW domain-binding protein 3),GO:0005794; GO:0050699; GO:0006915; GO:0071222; GO:0005765; GO:0042347; GO:0005886; GO:0043123; GO:0001817; GO:0006355; GO:0004871; GO:0006351,"Golgi apparatus; WW domain binding; apoptotic process; cellular response to lipopolysaccharide; lysosomal membrane; negative regulation of NF-kappaB import into nucleus; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of cytokine production; regulation of transcription, DNA-dependent; signal transducer activity; transcription, DNA-dependent",PF10601;,,,,,,,,,LITAF_MOUSE,Mus musculus (Mouse),"aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cytokine production [GO:0001817]; regulation of transcription, DNA-templated [GO:0006355]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]" comp147106_c0_seq1,228,36.8421,0.25964218,0,25,,3.00E-29,Q58CT4,Transmembrane protein 180,Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A),GO:0016021,integral to membrane,,,,,,,,,,TM180_BOVIN,Bos taurus (Bovine), comp147108_c0_seq1,380,46.0526,0.64796367,5,40,,2.00E-08,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,,,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp147117_c0_seq1,625,41.44,0.71307137,12,26,,3.00E-60,P97864,"Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11; Caspase-7, N-terminally processed]",Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11],GO:0004190; GO:0097153; GO:0005737; GO:0097194; GO:0007507; GO:0005634; GO:0043525; GO:0016485; GO:0006508; GO:0001836; GO:0009411,aspartic-type endopeptidase activity; cysteine-type endopeptidase activity involved in apoptotic process; cytoplasm; execution phase of apoptosis; heart development; nucleus; positive regulation of neuron apoptotic process; protein processing; proteolysis; release of cytochrome c from mitochondria; response to UV,,,,,,,,,,CASP7_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; heart development [GO:0007507]; neuron apoptotic process [GO:0051402]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411] comp147121_c0_seq1,522,43.6782,0.12908316,3,41,,,,,,,,,4.00E-12,CHOYP_LOC100632618.3.3,,,,,,,,, comp147128_c0_seq1,300,45.3333,0.21587617,4,17,,3.00E-26,Q9Y573,Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27),Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27),GO:0003779; GO:0015629; GO:0005737,actin binding; actin cytoskeleton; cytoplasm,PF07707;PF00651;PF01344;,,,,,,,,,IPP_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp147129_c0_seq1,275,64.3636,0.82700416,0,19,,1.00E-36,Q9C9C5,60S ribosomal protein L6-3,60S ribosomal protein L6-3,GO:0022625; GO:0005886; GO:0009506; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; plasma membrane; plasmodesma; structural constituent of ribosome; translation,PF01159;PF03868;,,,5.00E-11,ruditapes2_c5134,,,,,RL63_ARATH,Arabidopsis thaliana (Mouse-ear cress),cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] comp147136_c0_seq1,243,51.8519,0.51736895,1,16,,,,,,,,,6.00E-12,CHOYP_LOC100367356.1.1,,,,,,,,, comp147142_c0_seq1,212,42.9245,0.74626285,10,12,,6.00E-19,P13214,Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II),Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II),GO:0005509; GO:0005544,calcium ion binding; calcium-dependent phospholipid binding,PF00191;,6.00E-30,CHOYP_ANXA6.1.2,,,,,,,ANXA4_BOVIN,Bos taurus (Bovine),epithelial cell differentiation [GO:0030855]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp147153_c0_seq1,203,51.2315,0.24687973,3,10,,,,,,,,,6.00E-11,CHOYP_LOC577371.1.2,,,,,,,,, comp147156_c0_seq1,417,41.7266,0.34794873,19,9,,1.00E-23,Q8K2Y0,RING finger protein 219,RING finger protein 219,GO:0008270,zinc ion binding,,1.00E-23,CHOYP_RN219.3.3,,,,,,,RN219_MOUSE,Mus musculus (Mouse),"positive regulation of mRNA splicing, via spliceosome [GO:0048026]" comp147163_c0_seq1,560,38.9286,0.79744391,21,18,,3.00E-74,Q5REX1,Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2),Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2),GO:0005524; GO:0005737; GO:0007243; GO:0000287; GO:0046777; GO:0004674; GO:0046626,ATP binding; cytoplasm; intracellular protein kinase cascade; magnesium ion binding; protein autophosphorylation; protein serine/threonine kinase activity; regulation of insulin receptor signaling pathway,PF00069;,7.00E-79,CHOYP_SIK2.1.1,4.00E-73,ruditapes_c9662,,,,,SIK2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] comp147173_c0_seq1,237,42.1941,0.88550564,0,16,,3.00E-13,Q9XT73,"Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) [Cleaved into: Ferritin heavy chain, N-terminally processed]","Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) [Cleaved into: Ferritin heavy chain, N-terminally processed]",GO:0006879; GO:0008199; GO:0004322; GO:0006955; GO:0006826; GO:0008285,cellular iron ion homeostasis; ferric iron binding; ferroxidase activity; immune response; iron ion transport; negative regulation of cell proliferation,PF00210;,,,,,,,,,FRIH_TRIVU,Trichosurus vulpecula (Brush-tailed possum),cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; iron ion transport [GO:0006826]; negative regulation of cell proliferation [GO:0008285] comp147174_c0_seq1,433,41.3395,0.38271809,4,31,,6.00E-07,Q5FVF4,Transmembrane 7 superfamily member 3,Transmembrane 7 superfamily member 3,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF13886;,,,,,,,,,TM7S3_RAT,Rattus norvegicus (Rat), comp147179_c0_seq1,202,38.6139,0.42292703,0,18,,1.00E-06,Q9ERB4,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments),GO:0031103; GO:0005509; GO:0030246; GO:0007155; GO:0006928; GO:0031012; GO:0005540; GO:0030169; GO:0005578,axon regeneration; calcium ion binding; carbohydrate binding; cell adhesion; cellular component movement; extracellular matrix; hyaluronic acid binding; low-density lipoprotein particle binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_RAT,Rattus norvegicus (Rat),axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; response to wounding [GO:0009611]; skeletal system development [GO:0001501] comp147188_c0_seq1,305,44.2623,0.27818481,10,7,,7.00E-24,Q60821,Zinc finger and BTB domain-containing protein 17 (LP-1) (Polyomavirus late initiator promoter-binding protein) (Zinc finger protein 100) (Zfp-100) (Zinc finger protein 151) (Zinc finger protein Z13),Zinc finger and BTB domain-containing protein 17 (LP-1) (Polyomavirus late initiator promoter-binding protein) (Zinc finger protein 100) (Zfp-100) (Zinc finger protein 151) (Zinc finger protein Z13),GO:0003677; GO:0007398; GO:0001702; GO:0046872; GO:0005634; GO:0045893; GO:0003700; GO:0006351,"DNA binding; ectoderm development; gastrulation with mouth forming second; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT17_MOUSE,Mus musculus (Mouse),"ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitophagy [GO:1903146]; transcription, DNA-templated [GO:0006351]" comp147190_c0_seq1,253,45.0593,0.54877401,5,14,,3.00E-39,Q7SBD5,60S ribosomal protein L7,60S ribosomal protein L7,GO:0005840,ribosome,PF00327;PF08079;,1.00E-84,CHOYP_RL7.1.2,3.00E-52,ruditapes_lrc34372,,,,,RL7_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),"cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]" comp147199_c0_seq1,203,41.8719,0.79957147,3,10,,4.00E-19,Q92611,ER degradation-enhancing alpha-mannosidase-like protein 1,ER degradation-enhancing alpha-mannosidase-like protein 1,GO:0030433; GO:0006987; GO:0005509; GO:0030176; GO:0051787; GO:0043687; GO:0018279; GO:0006457,ER-associated protein catabolic process; activation of signaling protein activity involved in unfolded protein response; calcium ion binding; integral to endoplasmic reticulum membrane; misfolded protein binding; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding,PF01532;,1.00E-12,CHOYP_EDEM1.1.1,,,,,,,EDEM1_HUMAN,Homo sapiens (Human),"endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; IRE1-mediated unfolded protein response [GO:0036498]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on C branch [GO:0036510]" comp147206_c0_seq1,293,58.7031,0.83886847,0,30,,1.00E-37,P19824,"Phosphoribulokinase, chloroplastic (PRK) (PRKase) (EC 2.7.1.19) (Phosphopentokinase)","Phosphoribulokinase, chloroplastic (PRK) (PRKase) (EC 2.7.1.19) (Phosphopentokinase)",GO:0005524; GO:0000165; GO:0048046; GO:0009941; GO:0009902; GO:0009570; GO:0009535; GO:0019344; GO:0042742; GO:0050832; GO:0009595; GO:0009867; GO:0031348; GO:0006098; GO:0008974; GO:0009773; GO:0010207; GO:0006612; GO:0006364; GO:0019253; GO:0010310; GO:0043900; GO:0010363; GO:0035304; GO:0009637; GO:0010200; GO:0009409; GO:0010218; GO:0010114; GO:0009697; GO:0010103; GO:0010319; GO:0009862,"ATP binding; MAPK cascade; apoplast; chloroplast envelope; chloroplast relocation; chloroplast stroma; chloroplast thylakoid membrane; cysteine biosynthetic process; defense response to bacterium; defense response to fungus; detection of biotic stimulus; jasmonic acid mediated signaling pathway; negative regulation of defense response; pentose-phosphate shunt; phosphoribulokinase activity; photosynthetic electron transport in photosystem I; photosystem II assembly; protein targeting to membrane; rRNA processing; reductive pentose-phosphate cycle; regulation of hydrogen peroxide metabolic process; regulation of multi-organism process; regulation of plant-type hypersensitive response; regulation of protein dephosphorylation; response to blue light; response to chitin; response to cold; response to far red light; response to red light; salicylic acid biosynthetic process; stomatal complex morphogenesis; stromule; systemic acquired resistance, salicylic acid mediated signaling pathway",PF00485;,,,,,,,,,KPPR_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),reductive pentose-phosphate cycle [GO:0019253]; response to cytokinin [GO:0009735] comp147209_c0_seq1,370,43.7838,0.4019531,8,18,,4.00E-31,O95864,Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),Fatty acid desaturase 2 (EC 1.14.19.3) (Acyl-CoA 6-desaturase) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),GO:0036109; GO:0005789; GO:0020037; GO:0005887; GO:0005506; GO:0043651; GO:0004768; GO:0006636,alpha-linolenic acid metabolic process; endoplasmic reticulum membrane; heme binding; integral to plasma membrane; iron ion binding; linoleic acid metabolic process; stearoyl-CoA 9-desaturase activity; unsaturated fatty acid biosynthetic process,PF00173;PF00487;,1.00E-15,CHOYP_FADS2.2.2,,,,,,,FADS2_HUMAN,Homo sapiens (Human),alpha-linolenic acid metabolic process [GO:0036109]; linoleic acid metabolic process [GO:0043651]; unsaturated fatty acid biosynthetic process [GO:0006636] comp147215_c0_seq1,248,40.3226,0.42729137,2,18,,2.00E-31,P48544,"G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (IRK-4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5)","G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (IRK-4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5)",GO:0015467; GO:0007268; GO:0008076,G-protein activated inward rectifier potassium channel activity; synaptic transmission; voltage-gated potassium channel complex,PF01007;,2.00E-42,CHOYP_LOC100875023.1.1,,,,,,,IRK5_HUMAN,Homo sapiens (Human),potassium ion import [GO:0010107]; potassium ion transport [GO:0006813] comp147216_c0_seq1,244,46.7213,0.90742265,10,0,,8.00E-26,Q6V5K9,Zinc finger protein 474 (Testis-specific zinc finger protein) (TSZFP),Zinc finger protein 474 (Testis-specific zinc finger protein) (TSZFP),GO:0046872,metal ion binding,,3.00E-22,CHOYP_LOC100368109.1.1,,,,,,,ZN474_MOUSE,Mus musculus (Mouse), comp147225_c0_seq1,261,42.5287,0.25992445,7,21,,6.00E-19,Q9H1A4,Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),GO:0005680; GO:0031145; GO:0051301; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination,PF12859;,5.00E-19,CHOYP_APC1.3.3,,,,,,,APC1_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp147227_c0_seq1,396,44.1919,0.16459475,9,9,,1.00E-24,P68827,N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase),N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase),GO:0032580; GO:0003944; GO:0016021; GO:0006486,Golgi cisterna membrane; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity; integral to membrane; protein glycosylation,PF09992;,,,,,,,,,NAGPA_BOVIN,Bos taurus (Bovine),protein glycosylation [GO:0006486] comp147230_c0_seq1,502,40.8367,0.33552639,6,33,,8.00E-65,Q9WTN0,"Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)","Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)",GO:0005737; GO:0004161; GO:0045337; GO:0004311; GO:0033384; GO:0033386; GO:0004337; GO:0006720; GO:0046872,cytoplasm; dimethylallyltranstransferase activity; farnesyl diphosphate biosynthetic process; farnesyltranstransferase activity; geranyl diphosphate biosynthetic process; geranylgeranyl diphosphate biosynthetic process; geranyltranstransferase activity; isoprenoid metabolic process; metal ion binding,PF00348;,2.00E-47,CHOYP_GGPPS.1.1,,,,,,,GGPPS_MOUSE,Mus musculus (Mouse),farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid metabolic process [GO:0006720] comp147245_c0_seq1,209,51.6746,1.15387257,0,20,,1.00E-12,P31396,Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0000977; GO:0004879; GO:0007552; GO:0016319; GO:0000122; GO:0005634; GO:0045944; GO:0040034; GO:0003707; GO:0004887; GO:0008270,"RNA polymerase II regulatory region sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metamorphosis; mushroom body development; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of development, heterochronic; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,,,,,,,,,HR3_DROME,Drosophila melanogaster (Fruit fly),"metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]" comp147258_c0_seq1,285,37.8947,0.3957157,9,8,,,,,,,,,2.00E-13,CHOYP_LOC100577801.1.1,,,,,,,,, comp147291_c0_seq1,428,44.8598,0.88791334,5,23,,9.00E-38,Q8JIS3,D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),GO:0042732; GO:0050038; GO:0005737; GO:0047880,D-xylose metabolic process; L-xylulose reductase (NADP+) activity; cytoplasm; erythrulose reductase activity,,,,,,,,,,DER_CHICK,Gallus gallus (Chicken),D-xylose metabolic process [GO:0042732] comp147295_c0_seq1,285,36.4912,0.11842796,5,9,,7.00E-06,A2AHG0,Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1),Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1),GO:0030054; GO:0005737; GO:0014069; GO:0045211,cell junction; cytoplasm; postsynaptic density; postsynaptic membrane,,2.00E-24,CHOYP_PROSAPIP1.1.1,,,,,,,PRIP1_MOUSE,Mus musculus (Mouse), comp147297_c0_seq1,226,40.708,0.56300705,0,19,,3.00E-14,Q9CX98,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP2U1_MOUSE,Mus musculus (Mouse), comp147331_c0_seq1,237,44.7257,0.77610077,7,21,,4.00E-39,Q9VLS1,Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,1.00E-58,CHOYP_KPBB.2.2,,,,,,,KPBB_DROME,Drosophila melanogaster (Fruit fly),glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp147339_c0_seq1,225,44,0.29555946,2,8,,3.00E-08,O59028,Malate dehydrogenase (EC 1.1.1.37),Malate dehydrogenase (EC 1.1.1.37),GO:0030060; GO:0005737; GO:0006099,L-malate dehydrogenase activity; cytoplasm; tricarboxylic acid cycle,PF02615;,2.00E-22,CHOYP_LOC101069440.1.3,,,,,,,MDH_PYRHO,Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3),tricarboxylic acid cycle [GO:0006099] comp147355_c0_seq1,221,68.7783,0.96506932,0,25,,7.00E-10,P0AAQ9,Uncharacterized protein YbaA,Uncharacterized protein YbaA,,,PF07237;,,,,,,,,,YBAA_SHIFL,Shigella flexneri, comp147360_c0_seq1,265,43.3962,0.25333694,0,18,,3.00E-23,Q5T890,Putative DNA repair and recombination protein RAD26-like (EC 3.6.4.-),DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0005737; GO:0005815; GO:0005634,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; cytoplasm; microtubule organizing center; nucleus,PF00271;PF00176;PF14773;,,,,,,,,,RAD26_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281] comp147367_c0_seq1,326,46.0123,0.30843527,27,0,,,,,,,,,2.00E-38,CHOYP_BRAFLDRAFT_75956.1.1,,,,,,,,, comp147379_c0_seq1,201,44.2786,0.44939933,4,13,,2.00E-10,Q5VV43,Dyslexia-associated protein KIAA0319,Dyslexia-associated protein KIAA0319,GO:0005769; GO:0031901; GO:0016021; GO:2000171; GO:0001764; GO:0005886,early endosome; early endosome membrane; integral to membrane; negative regulation of dendrite development; neuron migration; plasma membrane,PF02010;,,,,,,,,,K0319_HUMAN,Homo sapiens (Human),negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764] comp147381_c0_seq1,289,62.6298,1.13337947,3,24,,3.00E-09,O06476,Uncharacterized ABC transporter ATP-binding protein YfmR (EC 3.6.3.-),Uncharacterized ABC transporter ATP-binding protein YfmR (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;PF16326;PF12848;,,,,,,,,,YFMR_BACSU,Bacillus subtilis (strain 168),transport [GO:0006810] comp147388_c0_seq1,278,32.3741,0.41518394,2,13,,1.00E-08,Q8CEL2,Uncharacterized protein C20orf26 homolog,Cilia- and flagella-associated protein 61,,,PF16092;,,,,,,,,,CT026_MOUSE,Mus musculus (Mouse), comp147399_c0_seq1,222,31.0811,0.75339367,2,17,,,,,,,,,4.00E-19,CHOYP_BRAFLDRAFT_119002.1.1,,,,,,,,, comp147408_c0_seq1,331,65.5589,0.85012725,0,35,,4.00E-18,A8J785,"ATP synthase subunit b', chloroplastic (ATP synthase F(0) sector subunit b') (ATPase subunit II)","ATP synthase subunit b', chloroplastic (ATP synthase F(0) sector subunit b') (ATPase subunit II)",GO:0005524; GO:0015986; GO:0000165; GO:0009941; GO:0009535; GO:0042742; GO:0050832; GO:0009595; GO:0019761; GO:0015078; GO:0016021; GO:0009867; GO:0031348; GO:0006098; GO:0009853; GO:0010207; GO:0009657; GO:0043085; GO:0006612; GO:0045263; GO:0006364; GO:0010310; GO:0043900; GO:0010363; GO:0035304; GO:0010200; GO:0009409; GO:0009697; GO:0009862,"ATP binding; ATP synthesis coupled proton transport; MAPK cascade; chloroplast envelope; chloroplast thylakoid membrane; defense response to bacterium; defense response to fungus; detection of biotic stimulus; glucosinolate biosynthetic process; hydrogen ion transmembrane transporter activity; integral to membrane; jasmonic acid mediated signaling pathway; negative regulation of defense response; pentose-phosphate shunt; photorespiration; photosystem II assembly; plastid organization; positive regulation of catalytic activity; protein targeting to membrane; proton-transporting ATP synthase complex, coupling factor F(o); rRNA processing; regulation of hydrogen peroxide metabolic process; regulation of multi-organism process; regulation of plant-type hypersensitive response; regulation of protein dephosphorylation; response to chitin; response to cold; salicylic acid biosynthetic process; systemic acquired resistance, salicylic acid mediated signaling pathway",PF00430;,,,,,,,,,ATPX_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),ATP synthesis coupled proton transport [GO:0015986]; response to cytokinin [GO:0009735] comp147411_c0_seq1,207,45.8937,0.75638129,3,14,,2.00E-16,Q08CZ0,Ubiquitin-protein ligase E3B (EC 6.3.2.-),Ubiquitin-protein ligase E3B (EC 6.3.2.-),GO:0004842,ubiquitin-protein ligase activity,PF00632;PF00612;,,,,,,,,,UBE3B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp147417_c0_seq1,344,43.314,0.81873638,0,22,,8.00E-06,Q8NCG7,Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L),Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L),GO:0019369; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0030168; GO:0004806,arachidonic acid metabolic process; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; platelet activation; triglyceride lipase activity,PF01764;,,,,,,,,,DGLB_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136] comp147420_c0_seq1,365,45.7534,0.57845262,4,22,,1.00E-08,Q14416,Metabotropic glutamate receptor 2 (mGluR2),Metabotropic glutamate receptor 2 (mGluR2),GO:0004930; GO:0030424; GO:0005246; GO:0030054; GO:0030425; GO:0008066; GO:0014047; GO:0001641; GO:0005887; GO:0005622; GO:0007194; GO:0042734; GO:0007268,G-protein coupled receptor activity; axon; calcium channel regulator activity; cell junction; dendrite; glutamate receptor activity; glutamate secretion; group II metabotropic glutamate receptor activity; integral to plasma membrane; intracellular; negative regulation of adenylate cyclase activity; presynaptic membrane; synaptic transmission,PF00003;PF01094;PF07562;,,,,,,,,,GRM2_HUMAN,Homo sapiens (Human),"adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; glutamate secretion [GO:0014047]; negative regulation of adenylate cyclase activity [GO:0007194]; regulation of synaptic transmission, glutamatergic [GO:0051966]" comp147423_c0_seq1,216,43.5185,0.50583835,1,16,,8.00E-15,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp147425_c0_seq1,499,41.6834,0.32386546,12,18,,5.00E-17,A4IH88,Uncharacterized protein KIAA2013 homolog,Uncharacterized protein KIAA2013 homolog,GO:0016021,integral to membrane,PF10222;,,,,,,,,,K2013_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp147428_c0_seq1,232,57.3276,1.00114931,0,19,,7.00E-11,O31215,Cytochrome b,Cytochrome b,GO:0009055; GO:0016021; GO:0046872; GO:0016491; GO:0005886; GO:0070469; GO:0022904,electron carrier activity; integral to membrane; metal ion binding; oxidoreductase activity; plasma membrane; respiratory chain; respiratory electron transport chain,PF00032;PF00033;,,,,,,,,,CYB_ALLVD,Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp147429_c0_seq1,231,41.5584,0.30261437,6,9,,7.00E-08,Q6ZT07,TBC1 domain family member 9 (TBC1 domain family member 9A),TBC1 domain family member 9 (TBC1 domain family member 9A),GO:0005097; GO:0005509; GO:0032851,Rab GTPase activator activity; calcium ion binding; positive regulation of Rab GTPase activity,PF02893;PF00566;,,,,,,,,,TBCD9_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp147447_c0_seq1,237,43.4599,0.45594681,2,18,,3.00E-07,Q8IVG5,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_HUMAN,Homo sapiens (Human), comp147448_c0_seq1,399,46.3659,0.42990478,8,23,,4.00E-08,O88871,Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51),Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51),GO:0004965; GO:0038039; GO:0030054; GO:0005737; GO:0007214; GO:0005887; GO:0043005; GO:0045211,G-protein coupled GABA receptor activity; G-protein coupled receptor heterodimeric complex; cell junction; cytoplasm; gamma-aminobutyric acid signaling pathway; integral to plasma membrane; neuron projection; postsynaptic membrane,PF00003;PF01094;,,,,,,,,,GABR2_RAT,Rattus norvegicus (Rat),gamma-aminobutyric acid signaling pathway [GO:0007214] comp147457_c0_seq1,248,37.5,0.46197412,0,17,,3.00E-09,O88277,Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),GO:0005509; GO:0005913; GO:0010631; GO:0007156; GO:0016021; GO:0005634; GO:0005886,calcium ion binding; cell-cell adherens junction; epithelial cell migration; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT2_RAT,Rattus norvegicus (Rat),epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp147469_c0_seq1,252,43.254,0.88462931,3,10,,8.00E-06,Q3MII6,TBC1 domain family member 25,TBC1 domain family member 25,GO:0005097; GO:0005776; GO:0006914; GO:0031410; GO:1901096,Rab GTPase activator activity; autophagic vacuole; autophagy; cytoplasmic vesicle; regulation of autophagic vacuole maturation,PF00566;,,,,,,,,,TBC25_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; regulation of autophagosome maturation [GO:1901096]; regulation of vesicle fusion [GO:0031338] comp14746_c0_seq1,246,47.9675,0.50029762,5,13,,5.00E-07,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp147487_c0_seq1,298,45.6376,0.32394731,10,12,,3.00E-33,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,2.00E-44,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp147495_c0_seq1,239,50.6276,0.60201723,2,18,,8.00E-06,P23049,Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2),Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2),GO:0005524; GO:0004715; GO:0018108,ATP binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF07714;,,,,,,,,,SEA_AVIET,Avian erythroblastosis virus (strain S13), comp147509_c0_seq1,278,64.0288,1.02199125,0,25,,2.00E-17,P55504,Uncharacterized protein y4jD,Uncharacterized protein y4jD,,,PF03050;PF13007;PF13005;,,,,,,,,,Y4JD_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234), comp147535_c0_seq1,218,61.4679,1.41608331,0,17,,3.00E-22,Q9CC91,Uncharacterized protein ML1105,Uncharacterized protein ML1105,,,PF03167;,,,,,,,,,Y1105_MYCLE,Mycobacterium leprae (strain TN), comp147537_c0_seq1,560,46.0714,0.43994832,15,19,,2.00E-86,Q8IUH5,Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17),Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17),GO:0030660; GO:0016021; GO:0042953; GO:0015095; GO:0043123; GO:0018345; GO:0019706; GO:0004871; GO:0008270,Golgi-associated vesicle membrane; integral to membrane; lipoprotein transport; magnesium ion transmembrane transporter activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation; protein-cysteine S-palmitoyltransferase activity; signal transducer activity; zinc ion binding,PF12796;PF01529;,3.00E-51,CHOYP_ZDH17.1.1,,,,,,,ZDH17_HUMAN,Homo sapiens (Human),lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345] comp147550_c0_seq1,256,42.9688,0.60451191,9,14,,2.00E-30,Q5U4S8,Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase),GO:0005794; GO:0000139; GO:0008120; GO:0046479; GO:0016021; GO:0007275,Golgi apparatus; Golgi membrane; ceramide glucosyltransferase activity; glycosphingolipid catabolic process; integral to membrane; multicellular organismal development,PF13506;,,,,,,,,,CEGTB_XENLA,Xenopus laevis (African clawed frog),glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275] comp147551_c0_seq1,364,39.5604,1.03693964,6,19,,5.00E-19,Q6UPE0,"Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)","Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)",GO:0008812; GO:0050660; GO:0019285; GO:0005743,choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline; mitochondrial inner membrane,PF05199;PF00732;,,,,,,,,,CHDH_RAT,Rattus norvegicus (Rat),glycine betaine biosynthetic process from choline [GO:0019285] comp147552_c0_seq1,419,38.6635,0.70513222,7,22,,7.00E-43,Q5RDB5,Protein cornichon homolog 1 (CNIH-1) (Cornichon family AMPA receptor auxiliary protein 1) (Protein cornichon homolog),Protein cornichon homolog 1 (CNIH-1) (Cornichon family AMPA receptor auxiliary protein 1) (Protein cornichon homolog),GO:0000139; GO:0005789; GO:0016021; GO:0035556; GO:0016192,Golgi membrane; endoplasmic reticulum membrane; integral to membrane; intracellular signal transduction; vesicle-mediated transport,PF03311;,6.00E-46,CHOYP_CNIH.1.1,,,,,,,CNIH_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),vesicle-mediated transport [GO:0016192] comp147554_c0_seq1,277,62.4549,1.22812846,0,20,,7.00E-10,A0QNG6,FHA domain-containing protein FhaB (FtsZ-interacting protein A),FHA domain-containing protein FhaB (FtsZ-interacting protein A),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF16697;,,,,,,,,,FHAB_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155), comp147558_c0_seq1,349,48.4241,0.6410309,3,18,,3.00E-11,Q8VCV9,Sodium-dependent glucose transporter 1A,Sodium-dependent glucose transporter 1A (Major facilitator superfamily domain-containing protein 4B1),GO:0016324; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,NAGTA_MOUSE,Mus musculus (Mouse),carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp147563_c0_seq1,381,49.0814,0.92356151,3,20,,1.00E-15,Q9H987,Synaptopodin 2-like protein,Synaptopodin 2-like protein,GO:0030018; GO:0005856; GO:0005634,Z disc; cytoskeleton; nucleus,PF00595;,,,,,,,,,SYP2L_HUMAN,Homo sapiens (Human),positive regulation of actin filament bundle assembly [GO:0032233] comp147575_c0_seq1,282,57.0922,1.22323242,0,17,,2.00E-40,P15106,Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase),GO:0005524; GO:0005737; GO:0004356; GO:0006542; GO:0009399,ATP binding; cytoplasm; glutamate-ammonia ligase activity; glutamine biosynthetic process; nitrogen fixation,PF00120;PF03951;,,,,,,,,,GLNA_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),glutamine biosynthetic process [GO:0006542]; nitrogen fixation [GO:0009399] comp147583_c0_seq1,291,68.3849,1.06204528,0,25,,5.00E-45,A1W4B9,Glutamyl-tRNA reductase (GluTR) (EC 1.2.1.70),Glutamyl-tRNA reductase (GluTR) (EC 1.2.1.70),GO:0050661; GO:0008883; GO:0006782,NADP binding; glutamyl-tRNA reductase activity; protoporphyrinogen IX biosynthetic process,PF00745;PF05201;PF01488;,,,,,,,,,HEM1_ACISJ,Acidovorax sp. (strain JS42),protoporphyrinogen IX biosynthetic process [GO:0006782] comp147590_c0_seq1,499,30.4609,0.27174022,4,42,,9.00E-28,Q3V6T2,Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),GO:0006260; GO:0005794; GO:0031929; GO:0003779; GO:0032148; GO:0016477; GO:0016023; GO:0031410; GO:0005829; GO:0005783; GO:0030027; GO:0030032; GO:0061024; GO:0008017; GO:0035091; GO:0005886; GO:0006275; GO:0032956; GO:0042127; GO:0010975,DNA replication; Golgi apparatus; TOR signaling cascade; actin binding; activation of protein kinase B activity; cell migration; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; endoplasmic reticulum; lamellipodium; lamellipodium assembly; membrane organization; microtubule binding; phosphatidylinositol binding; plasma membrane; regulation of DNA replication; regulation of actin cytoskeleton organization; regulation of cell proliferation; regulation of neuron projection development,PF05622;,,,,,,,,,GRDN_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp147599_c0_seq1,341,41.6422,0.58003467,5,18,,2.00E-14,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp147609_c0_seq1,301,42.1927,1.07256384,5,20,,7.00E-09,Q9NDG8,Acetylcholinesterase 4 (AChE 4) (EC 3.1.1.7),Acetylcholinesterase 4 (AChE 4) (EC 3.1.1.7),GO:0003990; GO:0004091; GO:0030054; GO:0005576; GO:0042135; GO:0005886; GO:0045202,acetylcholinesterase activity; carboxylesterase activity; cell junction; extracellular region; neurotransmitter catabolic process; plasma membrane; synapse,PF00135;,,,,,,,,,ACE4_CAEBR,Caenorhabditis briggsae,neurotransmitter catabolic process [GO:0042135] comp147613_c0_seq1,201,44.2786,0.62995322,2,11,,7.00E-22,Q8NE62,"Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)","Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)",GO:0008812; GO:0050660; GO:0019285; GO:0005743,choline dehydrogenase activity; flavin adenine dinucleotide binding; glycine betaine biosynthetic process from choline; mitochondrial inner membrane,PF05199;PF00732;,5.00E-11,CHOYP_LOC100877554.1.2,,,,,,,CHDH_HUMAN,Homo sapiens (Human),choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285] comp147614_c0_seq1,300,41,0.64627664,10,11,,9.00E-21,Q62132,Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Phosphotyrosine phosphatase 13) (Protein-tyrosine-phosphatase SL),Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Phosphotyrosine phosphatase 13) (Protein-tyrosine-phosphatase SL),GO:0009986; GO:0005737; GO:0001701; GO:0016021; GO:0005634; GO:0005886; GO:0019901; GO:0004725,cell surface; cytoplasm; in utero embryonic development; integral to membrane; nucleus; plasma membrane; protein kinase binding; protein tyrosine phosphatase activity,PF00102;,6.00E-19,CHOYP_LOC100374454.1.1,,,,,,,PTPRR_MOUSE,Mus musculus (Mouse),ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; neuron differentiation [GO:0030182]; protein dephosphorylation [GO:0006470] comp147617_c0_seq1,260,41.5385,0.27000399,4,9,,1.00E-11,Q5F3X0,Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51),Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51),GO:0003841; GO:0016024; GO:0005789; GO:0016021; GO:0007275,1-acylglycerol-3-phosphate O-acyltransferase activity; CDP-diacylglycerol biosynthetic process; endoplasmic reticulum membrane; integral to membrane; multicellular organismal development,PF16076;PF01553;,,,,,,,,,LCLT1_CHICK,Gallus gallus (Chicken),CDP-diacylglycerol biosynthetic process [GO:0016024]; multicellular organism development [GO:0007275] comp147631_c0_seq1,223,44.3946,0.54903065,1,18,,1.00E-09,Q8N4N3,Kelch-like protein 36,Kelch-like protein 36,GO:0016567,protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH36_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp147632_c0_seq1,308,47.0779,0.41153402,1,20,,8.00E-37,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,1.00E-33,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp147649_c0_seq1,277,45.4874,0.64072538,6,24,,5.00E-27,Q640S2,Protein cereblon,Protein cereblon,GO:0004176; GO:0031464; GO:0005737; GO:0005634; GO:0043161; GO:0016567,ATP-dependent peptidase activity; Cul4A-RING ubiquitin ligase complex; cytoplasm; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination,PF02190;PF03226;,,,,,,,,,CRBN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),embryonic pectoral fin morphogenesis [GO:0035118]; limb development [GO:0060173]; otic vesicle morphogenesis [GO:0071600]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] comp147653_c0_seq1,363,33.6088,0.30978959,1,22,,3.00E-09,Q9ESP5,Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like),Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like),GO:0000978; GO:0007411; GO:0007413; GO:0021853; GO:0016358; GO:0021542; GO:0021797; GO:0007626; GO:0046872; GO:0008285; GO:0000122; GO:0005634; GO:0045666; GO:0045893; GO:0006351,"RNA polymerase II core promoter proximal region sequence-specific DNA binding; axon guidance; axonal fasciculation; cerebral cortex GABAergic interneuron migration; dendrite development; dentate gyrus development; forebrain anterior/posterior pattern specification; locomotory behavior; metal ion binding; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,FEZF2_MOUSE,Mus musculus (Mouse),"axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cerebral cortex GABAergic interneuron migration [GO:0021853]; cerebral cortex neuron differentiation [GO:0021895]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; dendrite development [GO:0016358]; dentate gyrus development [GO:0021542]; forebrain anterior/posterior pattern specification [GO:0021797]; forebrain development [GO:0030900]; locomotory behavior [GO:0007626]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron fate determination [GO:0048664]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of axon guidance [GO:1902667]; telencephalon development [GO:0021537]" comp147659_c0_seq1,269,40.1487,0.38961577,3,14,,4.00E-20,Q5DTV4,Probable ribonuclease ZC3H12C (EC 3.1.-.-) (Zinc finger CCCH domain-containing protein 12C),Probable ribonuclease ZC3H12C (EC 3.1.-.-) (Zinc finger CCCH domain-containing protein 12C),GO:0004519; GO:0046872; GO:0090305,endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF11977;,1.00E-32,CHOYP_LOC101065570.1.1,,,,,,,ZC12C_MOUSE,Mus musculus (Mouse), comp147687_c0_seq1,621,40.9018,0.15472677,23,7,,2.00E-43,Q3V384,Lactation elevated protein 1,Lactation elevated protein 1,GO:0005524; GO:0005739,ATP binding; mitochondrion,PF03969;,3.00E-40,CHOYP_LOC100642494.1.1,,,,,,,LACE1_MOUSE,Mus musculus (Mouse), comp147697_c0_seq1,215,40.4651,1.14530579,1,18,,6.00E-11,P51521,Protein ovo (Protein shaven baby),Protein ovo (Protein shaven baby),GO:0008343; GO:0035017; GO:0048067; GO:0005737; GO:0007010; GO:0019099; GO:0016348; GO:0046872; GO:0000122; GO:0035316; GO:0005634; GO:0048477; GO:0045944; GO:0070896; GO:0008360; GO:0043565; GO:0000981,adult feeding behavior; cuticle pattern formation; cuticle pigmentation; cytoplasm; cytoskeleton organization; female germ-line sex determination; imaginal disc-derived leg joint morphogenesis; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; non-sensory hair organization; nucleus; oogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transposon integration; regulation of cell shape; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity,,,,,,,,,,OVO_DROME,Drosophila melanogaster (Fruit fly),"adult feeding behavior [GO:0008343]; cuticle development [GO:0042335]; cuticle pattern formation [GO:0035017]; cuticle pigmentation [GO:0048067]; cytoskeleton organization [GO:0007010]; epidermal cell differentiation [GO:0009913]; female germ-line sex determination [GO:0019099]; germ-line sex determination [GO:0018992]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; non-sensory hair organization [GO:0035316]; oogenesis [GO:0048477]; pheromone metabolic process [GO:0042810]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transposon integration [GO:0070896]; regulation of cell shape [GO:0008360]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp147701_c0_seq1,255,43.1373,0.68267717,3,15,,2.00E-19,Q811B3,A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,1.00E-32,CHOYP_BRAFLDRAFT_85817.1.1,,,,,,,ATS12_MOUSE,Mus musculus (Mouse),cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of cellular response to hepatocyte growth factor stimulus [GO:2001113]; negative regulation of cellular response to vascular endothelial growth factor stimulus [GO:1902548]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of hepatocyte growth factor receptor signaling pathway [GO:1902203]; proteoglycan catabolic process [GO:0030167]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of inflammatory response [GO:0050727] comp147704_c0_seq1,216,43.9815,1.22601498,0,18,,2.00E-23,Q95ZJ1,Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),GO:0000139; GO:0016021; GO:0004653; GO:0018243,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation via threonine,PF00535;PF00652;,,,,,,,,,GALT5_CAEEL,Caenorhabditis elegans,protein O-linked glycosylation via threonine [GO:0018243] comp147710_c0_seq1,240,37.5,0.59981131,10,13,,1.00E-10,Q6DCU6,Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R),Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R),GO:0000247; GO:0005789; GO:0006696; GO:0016021; GO:0006869; GO:0005637; GO:0005640; GO:0005886,C-8 sterol isomerase activity; endoplasmic reticulum membrane; ergosterol biosynthetic process; integral to membrane; lipid transport; nuclear inner membrane; nuclear outer membrane; plasma membrane,PF04622;,,,,,,,,,SGMR1_XENLA,Xenopus laevis (African clawed frog),lipid transport [GO:0006869] comp147713_c0_seq1,228,57.0175,1.13824675,0,13,,1.00E-23,P37791,Putative UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22),Putative UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22),GO:0051287; GO:0003979; GO:0006065; GO:0009103,NAD binding; UDP-glucose 6-dehydrogenase activity; UDP-glucuronate biosynthetic process; lipopolysaccharide biosynthetic process,PF00984;PF03721;,,,,,,,,,UDG_SHIFL,Shigella flexneri,lipopolysaccharide biosynthetic process [GO:0009103]; UDP-glucuronate biosynthetic process [GO:0006065] comp147717_c0_seq1,363,46.0055,0.73113898,1,27,,4.00E-39,Q9I8D1,Unconventional myosin-VI (Unconventional myosin-6),Unconventional myosin-VI (Unconventional myosin-6),GO:0043531; GO:0005524; GO:0030330; GO:0016591; GO:0005794; GO:0051015; GO:0030048; GO:0005516; GO:0005938; GO:0030136; GO:0030665; GO:0005905; GO:0006897; GO:0031941; GO:0030175; GO:0006886; GO:0005902; GO:0016459; GO:0031965; GO:0048471; GO:0060002; GO:0045944; GO:0051046; GO:0001726; GO:0032587; GO:0007605,"ADP binding; ATP binding; DNA damage response, signal transduction by p53 class mediator; DNA-directed RNA polymerase II, holoenzyme; Golgi apparatus; actin filament binding; actin filament-based movement; calmodulin binding; cell cortex; clathrin-coated vesicle; clathrin-coated vesicle membrane; coated pit; endocytosis; filamentous actin; filopodium; intracellular protein transport; microvillus; myosin complex; nuclear membrane; perinuclear region of cytoplasm; plus-end directed microfilament motor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of secretion; ruffle; ruffle membrane; sensory perception of sound",PF16521;PF00063;,4.00E-47,CHOYP_MYO6.1.1,,,,,,,MYO6_CHICK,Gallus gallus (Chicken),"actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]" comp147723_c0_seq1,662,45.4683,0.35266038,25,12,,5.00E-48,Q9TZM3,"Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)","Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)",GO:0005524; GO:0005525; GO:0005794; GO:0048846; GO:0034613; GO:0046872; GO:0043025; GO:0004674; GO:0034976; GO:0006979; GO:0007264; GO:0048489,ATP binding; GTP binding; Golgi apparatus; axon extension involved in axon guidance; cellular protein localization; metal ion binding; neuronal cell body; protein serine/threonine kinase activity; response to endoplasmic reticulum stress; response to oxidative stress; small GTPase mediated signal transduction; synaptic vesicle transport,PF12796;PF16095;PF13855;PF00069;PF08477;,6.00E-17,CHOYP_PHUM_PHUM346120.1.1,,,,,,,LRK1_CAEEL,Caenorhabditis elegans,axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489] comp147725_c0_seq1,206,47.5728,0.65715834,1,9,,,,,,,,,8.00E-41,CHOYP_LOC100374487.5.5,5.00E-22,ruditapes_lrc36854,,,,,,, comp147727_c0_seq1,295,45.7627,0.52459619,6,10,,4.00E-32,Q8N5D0,WD and tetratricopeptide repeats protein 1,WD and tetratricopeptide repeats protein 1,GO:0055082; GO:0032869; GO:0005829; GO:0004857; GO:0006006; GO:0001701; GO:0043231; GO:0035264; GO:0045717; GO:0000122; GO:0005634; GO:0008361,cellular chemical homeostasis; cellular response to insulin stimulus; cytosol; enzyme inhibitor activity; glucose metabolic process; in utero embryonic development; intracellular membrane-bounded organelle; multicellular organism growth; negative regulation of fatty acid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of cell size,PF00400;,2.00E-37,CHOYP_ISCW_ISCW007151.2.2,,,,,,,WDTC1_HUMAN,Homo sapiens (Human),cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361] comp147733_c0_seq1,220,33.1818,0.99701308,4,10,,3.00E-21,Q5R774,Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2),Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2),GO:0031463; GO:0005737; GO:0005634; GO:0010499; GO:0016567; GO:0006355; GO:0006351,"Cul3-RING ubiquitin ligase complex; cytoplasm; nucleus; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07707;PF00651;PF01344;,1.00E-19,CHOYP_KEAP1.1.1,,,,,,,KEAP1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp147736_c0_seq1,210,48.5714,0.99218551,2,13,,1.00E-11,O75452,Retinol dehydrogenase 16 (EC 1.1.-.-) (Microsomal NAD(+)-dependent retinol dehydrogenase 4) (RoDH-4) (Sterol/retinol dehydrogenase),Retinol dehydrogenase 16 (EC 1.1.-.-) (Microsomal NAD(+)-dependent retinol dehydrogenase 4) (RoDH-4) (Short chain dehydrogenase/reductase family 9C member 8) (Sterol/retinol dehydrogenase),GO:0009055; GO:0005789; GO:0016021; GO:0043231; GO:0006629; GO:0004745,electron carrier activity; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bounded organelle; lipid metabolic process; retinol dehydrogenase activity,PF00106;,,,,,,,,,RDH16_HUMAN,Homo sapiens (Human),lipid metabolic process [GO:0006629] comp147737_c0_seq1,278,44.964,0.28792942,8,11,,5.00E-09,Q9DBQ7,Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3),Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3),GO:0005524; GO:0005794; GO:0030027; GO:0004672,ATP binding; Golgi apparatus; lamellipodium; protein kinase activity,PF00069;,,,,,,,,,PACE1_MOUSE,Mus musculus (Mouse), comp147738_c0_seq1,249,38.1526,0.45167847,5,14,,1.00E-30,Q6IQ20,N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),GO:0070290; GO:0009395; GO:0042622; GO:0008270,NAPE-specific phospholipase D activity; phospholipid catabolic process; photoreceptor outer segment membrane; zinc ion binding,PF12706;,,,,,,,,,NAPEP_HUMAN,Homo sapiens (Human),phospholipid catabolic process [GO:0009395]; retinoid metabolic process [GO:0001523] comp147740_c0_seq1,803,42.5903,0.68823938,29,15,,7.00E-31,O00329,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)",GO:0016303; GO:0035005; GO:0005524; GO:0042113; GO:0035754; GO:0001782; GO:0050853; GO:0038095; GO:0010818; GO:0030217; GO:0050852; GO:0002250; GO:0001816; GO:0007173; GO:0008543; GO:0006954; GO:0045087; GO:0002551; GO:0043303; GO:0060374; GO:0035747; GO:0001779; GO:0048011; GO:0030593; GO:0072672; GO:0014065; GO:0005942; GO:0046934; GO:0005886; GO:0006468; GO:0002679; GO:0044281,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; B cell activation; B cell chemotaxis; B cell homeostasis; B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; T cell chemotaxis; T cell differentiation; T cell receptor signaling pathway; adaptive immune response; cytokine production; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; inflammatory response; innate immune response; mast cell chemotaxis; mast cell degranulation; mast cell differentiation; natural killer cell chemotaxis; natural killer cell differentiation; neurotrophin TRK receptor signaling pathway; neutrophil chemotaxis; neutrophil extravasation; phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; plasma membrane; protein phosphorylation; respiratory burst involved in defense response; small molecule metabolic process",PF00454;PF00792;PF02192;PF00794;PF00613;,,,,,,,,,PK3CD_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell chemotaxis [GO:0035754]; B cell receptor signaling pathway [GO:0050853]; cytokine production [GO:0001816]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell chemotaxis [GO:0002551]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; natural killer cell activation [GO:0030101]; natural killer cell chemotaxis [GO:0035747]; natural killer cell differentiation [GO:0001779]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; respiratory burst involved in defense response [GO:0002679]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] comp147742_c0_seq1,360,42.7778,0.80017668,9,14,,,,,,,,,1.00E-41,CHOYP_ACLY.1.1,,,,,,,,, comp147744_c0_seq1,337,43.9169,0.25247655,4,21,,3.00E-09,Q8R508,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT3_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp147755_c0_seq1,390,38.2051,0.35494061,6,28,,5.00E-37,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,7.00E-20,CHOYP_MAN2A1.1.1,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp147757_c0_seq1,390,47.6923,0.49872777,24,0,,3.00E-13,G5E8K5,Ankyrin-3 (ANK-3) (Ankyrin-G),Ankyrin-3 (ANK-3) (Ankyrin-G),GO:0007411; GO:0043194; GO:0005856; GO:0014704; GO:0005764; GO:0016020; GO:0033268; GO:0033270; GO:0045760; GO:0045211; GO:0072661; GO:0019228; GO:0042383; GO:0007165; GO:0045202; GO:0050808,axon guidance; axon initial segment; cytoskeleton; intercalated disc; lysosome; membrane; node of Ranvier; paranode region of axon; positive regulation of action potential; postsynaptic membrane; protein targeting to plasma membrane; regulation of action potential in neuron; sarcolemma; signal transduction; synapse; synapse organization,PF00023;PF12796;PF13606;PF00531;PF00791;,9.00E-31,CHOYP_LOC100369608.3.3,,,,,,,ANK3_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808] comp147760_c0_seq1,227,67.4009,1.05196847,0,21,,1.00E-19,P26724,Uncharacterized 13.2 kDa HIT-like protein in hisE 3'region (ORF2),Uncharacterized 13.2 kDa HIT-like protein in hisE 3'region (ORF2),GO:0003824; GO:0008152,catalytic activity; metabolic process,PF01230;,,,,,,,,,YHIT_AZOBR,Azospirillum brasilense, comp147766_c0_seq1,245,46.1224,0.77800158,0,23,,8.00E-06,P16895,Elastase inhibitor,PI-actitoxin-Avd5a (PI-AITX-Avd5a) (Non-classical Kazal-type elastase inhibitor),GO:0004867,serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,IELA_ANESU,Anemonia sulcata (Mediterranean snakelocks sea anemone), comp147770_c0_seq1,207,49.2754,0.32037713,16,0,,4.00E-30,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp147771_c0_seq1,387,62.2739,1.20348198,0,22,,2.00E-35,A0QVB4,Tyrosine recombinase XerC,Tyrosine recombinase XerC,GO:0003677; GO:0007049; GO:0051301; GO:0007059; GO:0005737; GO:0006313; GO:0009037,"DNA binding; cell cycle; cell division; chromosome segregation; cytoplasm; transposition, DNA-mediated; tyrosine-based site-specific recombinase activity",PF02899;PF00589;,,,,,,,,,XERC_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),"cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; transposition, DNA-mediated [GO:0006313]" comp147774_c0_seq1,291,48.7973,0.81891993,2,21,,5.00E-14,Q09225,Nose resistant to fluoxetine protein 6 (Protein nrf-6),Nose resistant to fluoxetine protein 6 (Protein nrf-6),GO:0016021; GO:0008289; GO:0006869; GO:0007275; GO:0016747,"integral to membrane; lipid binding; lipid transport; multicellular organismal development; transferase activity, transferring acyl groups other than amino-acyl groups",PF01757;,,,,,,,,,NRF6_CAEEL,Caenorhabditis elegans,lipid transport [GO:0006869]; multicellular organism development [GO:0007275] comp147781_c0_seq1,301,42.8571,0.51063366,7,13,,6.00E-07,Q8N3F9,Integral membrane protein GPR137C (Transmembrane 7 superfamily member 1-like 2 protein),Integral membrane protein GPR137C (Transmembrane 7 superfamily member 1-like 2 protein),GO:0016021,integral to membrane,,,,,,,,,,G137C_HUMAN,Homo sapiens (Human), comp147784_c0_seq1,408,38.7255,0.3295749,0,26,,5.00E-26,Q80UX8,Alpha/beta hydrolase domain-containing protein 13 (Abhydrolase domain-containing protein 13) (EC 3.-.-.-),Protein ABHD13 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 13) (Abhydrolase domain-containing protein 13),GO:0016787; GO:0016021,hydrolase activity; integral to membrane,PF12146;,,,,,,,,,ABHDD_MOUSE,Mus musculus (Mouse), comp147787_c0_seq1,481,49.6881,0.66279889,5,24,,9.00E-34,Q296F7,Glutamate [NMDA] receptor subunit 1,Glutamate [NMDA] receptor subunit 1,GO:0017146; GO:0055074; GO:0030054; GO:0005234; GO:0004970; GO:0007616; GO:0008355; GO:0014069; GO:0045211; GO:0042391; GO:0007268,N-methyl-D-aspartate selective glutamate receptor complex; calcium ion homeostasis; cell junction; extracellular-glutamate-gated ion channel activity; ionotropic glutamate receptor activity; long-term memory; olfactory learning; postsynaptic density; postsynaptic membrane; regulation of membrane potential; synaptic transmission,PF01094;PF10562;PF00060;PF10613;,3.00E-44,CHOYP_LOC100533321.1.1,,,,,,,NMDA1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),calcium ion homeostasis [GO:0055074]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term memory [GO:0007616]; olfactory learning [GO:0008355]; regulation of membrane potential [GO:0042391] comp147808_c0_seq1,269,40.1487,0.48301204,2,13,,,,,,,,,3.00E-29,CHOYP_BRAFLDRAFT_128311.2.2,,,,,,,,, comp147812_c0_seq1,204,40.1961,0.49044241,7,0,,1.00E-10,Q9JKV2,Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK),Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK),GO:0005524; GO:0004693; GO:0005829; GO:0043231; GO:0007243; GO:0000287; GO:0007275; GO:0004674,ATP binding; cyclin-dependent protein serine/threonine kinase activity; cytosol; intracellular membrane-bounded organelle; intracellular protein kinase cascade; magnesium ion binding; multicellular organismal development; protein serine/threonine kinase activity,PF00069;,,,,,,,,,ICK_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; intracellular signal transduction [GO:0035556]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] comp147819_c0_seq1,229,62.0087,1.18841694,0,16,,7.00E-11,P42593,"2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) (2,4-dienoyl coenzyme A reductase)","2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) (2,4-dienoyl coenzyme A reductase)",GO:0008670; GO:0051539; GO:0010181; GO:0046872,"2,4-dienoyl-CoA reductase (NADPH) activity; 4 iron, 4 sulfur cluster binding; FMN binding; metal ion binding",PF00724;PF07992;,,,,,,,,,FADH_ECOLI,Escherichia coli (strain K12),"fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway [GO:0033543]" comp147823_c0_seq1,293,43.686,0.94139028,14,5,,5.00E-25,Q28224,Insulin receptor substrate 1 (IRS-1),Insulin receptor substrate 1 (IRS-1),GO:0042169; GO:0005737; GO:0005158; GO:0008286; GO:0005159; GO:0048009; GO:0005634; GO:0043548; GO:0005543; GO:0004871,SH2 domain binding; cytoplasm; insulin receptor binding; insulin receptor signaling pathway; insulin-like growth factor receptor binding; insulin-like growth factor receptor signaling pathway; nucleus; phosphatidylinositol 3-kinase binding; phospholipid binding; signal transducer activity,PF02174;PF00169;,1.00E-14,CHOYP_BRAFLDRAFT_124878.1.1,,,,,,,IRS1_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),insulin-like growth factor receptor signaling pathway [GO:0048009] comp147826_c0_seq1,460,46.7391,0.68243095,11,14,,,,,,,,,1.00E-35,CHOYP_BRAFLDRAFT_121518.1.1,,,,,,,,, comp147846_c0_seq1,357,57.423,1.09168,1,20,,1.00E-47,P55037,Ferredoxin-dependent glutamate synthase 1 (EC 1.4.7.1) (Fd-GOGAT),Ferredoxin-dependent glutamate synthase 1 (EC 1.4.7.1) (Fd-GOGAT),GO:0051538; GO:0097054; GO:0016041; GO:0006541; GO:0046872,"3 iron, 4 sulfur cluster binding; L-glutamate biosynthetic process; glutamate synthase (ferredoxin) activity; glutamine metabolic process; metal ion binding",PF00310;PF04898;PF01645;PF01493;,,,,,,,,,GLTB_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054] comp147853_c0_seq1,263,45.2471,0.52292776,5,12,,1.00E-14,P81559,Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1),Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1),GO:0030284; GO:0005634; GO:0043565; GO:0003700; GO:0005496; GO:0006351; GO:0008270,"estrogen receptor activity; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; transcription, DNA-dependent; zinc ion binding",PF12743;PF00104;PF02159;PF00105;,1.00E-21,CHOYP_ER.2.2,,,,,,,ESR1_XENLA,Xenopus laevis (African clawed frog),"transcription, DNA-templated [GO:0006351]" comp147858_c0_seq1,408,41.1765,0.53448847,1,28,,6.00E-44,P28492,"Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)","Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)",GO:0004359; GO:0006541; GO:0005759; GO:0072593; GO:0042981,glutaminase activity; glutamine metabolic process; mitochondrial matrix; reactive oxygen species metabolic process; regulation of apoptotic process,PF12796;PF04960;,,,,,,,,,GLSL_RAT,Rattus norvegicus (Rat),glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543] comp147868_c0_seq1,483,44.3064,0.51014711,8,14,,7.00E-73,Q6WV17,Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),GO:0000139; GO:0005795; GO:0016021; GO:0009312; GO:0004653; GO:0006486,Golgi membrane; Golgi stack; integral to membrane; oligosaccharide biosynthetic process; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,1.00E-61,CHOYP_GLT13.2.2,,,,,,,GALT5_DROME,Drosophila melanogaster (Fruit fly),oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] comp147873_c0_seq1,496,43.5484,0.64052155,22,6,,9.00E-43,C0HAC0,F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5),F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5),GO:0019005; GO:0031146; GO:0005506; GO:0055072; GO:0048471; GO:0016567,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; iron ion binding; iron ion homeostasis; perinuclear region of cytoplasm; protein ubiquitination,PF12937;PF01814;PF13516;,3.00E-25,CHOYP_BRAFLDRAFT_115491.1.1,,,,,,,FBXL5_SALSA,Salmo salar (Atlantic salmon),iron ion homeostasis [GO:0055072]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp147879_c0_seq1,265,39.2453,0.29787658,10,11,,,,,,,,,,,3.00E-14,ruditapes2_c1288,,,,,,, comp147890_c0_seq1,219,39.726,0.48835646,11,4,,4.00E-20,Q9FHN8,Kinesin-like calmodulin-binding protein (Protein ZWICHEL),Kinesin-like calmodulin-binding protein (Protein ZWICHEL),GO:0043531; GO:0005524; GO:0016887; GO:0005509; GO:0005516; GO:0005871; GO:0008017; GO:0003777; GO:0007018; GO:0016491; GO:0010091,ADP binding; ATP binding; ATPase activity; calcium ion binding; calmodulin binding; kinesin complex; microtubule binding; microtubule motor activity; microtubule-based movement; oxidoreductase activity; trichome branching,PF00373;PF09379;PF00225;PF00784;,8.00E-41,CHOYP_LOC373208.1.1,,,,,,,KCBP_ARATH,Arabidopsis thaliana (Mouse-ear cress),microtubule-based movement [GO:0007018]; trichome branching [GO:0010091] comp147898_c0_seq1,299,47.1572,0.72522971,0,20,,,,,,,,,,,4.00E-12,ruditapes_c28681,,,,,,, comp147908_c0_seq1,298,41.6107,0.26359392,14,6,,9.00E-15,Q2TAC2,Coiled-coil domain-containing protein 57,Coiled-coil domain-containing protein 57,,,,5.00E-26,CHOYP_LOC100368744.1.1,,,,,,,CCD57_HUMAN,Homo sapiens (Human), comp147935_c0_seq1,216,42.5926,0.55727954,1,16,,5.00E-16,P53004,Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase),Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase),GO:0004074; GO:0005829; GO:0042167; GO:0044281; GO:0008270,biliverdin reductase activity; cytosol; heme catabolic process; small molecule metabolic process; zinc ion binding,PF09166;PF01408;,,,,,,,,,BIEA_HUMAN,Homo sapiens (Human),heme catabolic process [GO:0042167]; oxidation-reduction process [GO:0055114] comp147942_c0_seq1,635,44.252,0.87123504,18,22,,2.00E-33,Q5JS13,Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (Ral guanine nucleotide exchange factor 2) (RalGEF 2) (RalA exchange factor RalGPS1),Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (Ral guanine nucleotide exchange factor 2) (RalGEF 2) (RalA exchange factor RalGPS1),GO:0008321; GO:0005737; GO:0035556; GO:0005543; GO:0005886; GO:0032485; GO:0007264,Ral guanyl-nucleotide exchange factor activity; cytoplasm; intracellular signal transduction; phospholipid binding; plasma membrane; regulation of Ral protein signal transduction; small GTPase mediated signal transduction,PF00169;PF00617;,,,,,,,,,RGPS1_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264] comp147947_c0_seq1,463,45.3564,0.17234735,4,33,,6.00E-11,E1BP74,Meiosis arrest female protein 1 (Limkain-b1),Meiosis arrest female protein 1 (Limkain-b1),GO:0003723; GO:0030154; GO:0007143; GO:0010923; GO:0000166; GO:0048477; GO:0005777; GO:0010468,RNA binding; cell differentiation; female meiosis; negative regulation of phosphatase activity; nucleotide binding; oogenesis; peroxisome; regulation of gene expression,PF11608;PF01936;PF12872;,,,,,,,,,MARF1_BOVIN,Bos taurus (Bovine),double-strand break repair [GO:0006302]; female meiotic division [GO:0007143]; negative regulation of phosphatase activity [GO:0010923]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] comp147959_c0_seq1,304,44.0789,0.27397557,6,15,,3.00E-13,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp147963_c0_seq1,521,47.2169,0.5175852,18,8,,3.00E-37,Q8K1P8,Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2),Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2),GO:0016021; GO:0005886; GO:0015293; GO:0015349,integral to membrane; plasma membrane; symporter activity; thyroid hormone transmembrane transporter activity,PF07690;,,,,,,,,,MOT8_RAT,Rattus norvegicus (Rat),hormone transport [GO:0009914]; ion transmembrane transport [GO:0034220]; thyroid hormone transport [GO:0070327] comp147967_c0_seq1,214,47.6636,0.66155291,2,10,,5.00E-15,Q7Z494,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0003283; GO:0060271; GO:0060027; GO:0071908; GO:0071910; GO:0035469; GO:0071909; GO:0060287; GO:0007163; GO:0030198; GO:0001947; GO:0060993; GO:0006629; GO:0030324; GO:0048496; GO:0090090; GO:0045494; GO:0072372; GO:0030814; GO:2000167; GO:0072189,Wnt receptor signaling pathway; atrial septum development; cilium morphogenesis; convergent extension involved in gastrulation; determination of intestine left/right asymmetry; determination of liver left/right asymmetry; determination of pancreatic left/right asymmetry; determination of stomach left/right asymmetry; epithelial cilium movement involved in determination of left/right asymmetry; establishment or maintenance of cell polarity; extracellular matrix organization; heart looping; kidney morphogenesis; lipid metabolic process; lung development; maintenance of organ identity; negative regulation of canonical Wnt receptor signaling pathway; photoreceptor cell maintenance; primary cilium; regulation of cAMP metabolic process; regulation of planar cell polarity pathway involved in neural tube closure; ureter development,PF13176;,,,,,,,,,NPHP3_HUMAN,Homo sapiens (Human),"atrial septum development [GO:0003283]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lung development [GO:0030324]; maintenance of organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055]" comp147978_c0_seq1,334,50.8982,0.46425028,7,9,,,,,,,,,5.00E-33,CHOYP_LOC100179357.6.6,,,,,,,,, comp147991_c0_seq1,205,68.7805,1.04253493,0,15,,1.00E-12,B3R5N3,Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS),Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS),GO:0005524; GO:0005737; GO:0004819; GO:0006425; GO:0006424,ATP binding; cytoplasm; glutamine-tRNA ligase activity; glutaminyl-tRNA aminoacylation; glutamyl-tRNA aminoacylation,PF00749;PF03950;,,,,,,,,,SYQ_CUPTR,Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424)),glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424] comp147992_c0_seq1,264,42.803,0.19414198,7,15,,,,,,,,,,,5.00E-11,ruditapes2_c3065,,,,,,, comp147993_c0_seq1,218,44.0367,0.2882904,5,9,,6.00E-11,Q9CXF4,TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),GO:0005097; GO:0005576; GO:0005739,Rab GTPase activator activity; extracellular region; mitochondrion,PF12068;PF00566;,2.00E-22,CHOYP_TBC15.1.1,,,,,,,TBC15_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338] comp148004_c0_seq1,322,42.236,0.55991873,15,11,,,,,,,,,1.00E-21,CHOYP_ENPL.1.4,,,,,,,,, comp148009_c0_seq1,486,35.5967,0.19558316,5,24,,1.00E-40,Q4VBD9,GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GO:0001658; GO:0005737; GO:0046872; GO:0000122; GO:0005730; GO:0005634; GO:0043565; GO:0006351,"branching involved in ureteric bud morphogenesis; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,GZF1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp148026_c0_seq1,221,44.7964,1.26963384,1,20,,,,,,,,,,,4.00E-11,ruditapes_c7836,,,,,,, comp148029_c0_seq1,213,46.4789,0.52537983,6,10,,8.00E-15,Q502I6,Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R),Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R),GO:0004128; GO:0005783; GO:0020037; GO:0046872,"cytochrome-b5 reductase activity, acting on NAD(P)H; endoplasmic reticulum; heme binding; metal ion binding",PF00173;PF00970;PF00175;,,,,,,,,,NB5R4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),generation of precursor metabolites and energy [GO:0006091]; superoxide metabolic process [GO:0006801] comp148035_c0_seq1,392,44.1327,0.75370354,4,22,,,,,,,,,8.00E-38,CHOYP_LOC100641267.2.2,6.00E-31,ruditapes_c26815,,,,,,, comp148039_c0_seq1,402,43.2836,0.43165349,8,15,,2.00E-48,Q8R418,Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1),Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1),GO:0005524; GO:0008026; GO:0016442; GO:0001525; GO:0048754; GO:0055013; GO:0021987; GO:0005737; GO:0051607; GO:0035116; GO:0071335; GO:0031069; GO:0060119; GO:0060576; GO:0030324; GO:0046872; GO:0035198; GO:0035264; GO:0010626; GO:0000122; GO:0021675; GO:0048812; GO:0021889; GO:0032290; GO:0014040; GO:2000630; GO:0031643; GO:0045944; GO:0009791; GO:0031054; GO:0030422; GO:0016075; GO:0008593; GO:0051726; GO:0070173; GO:0045664; GO:0048713; GO:0001932; GO:0045069; GO:0004525; GO:0021522; GO:0051225; GO:0048536; GO:0019827; GO:0030423; GO:0010070,ATP binding; ATP-dependent helicase activity; RISC complex; angiogenesis; branching morphogenesis of an epithelial tube; cardiac muscle cell development; cerebral cortex development; cytoplasm; defense response to virus; embryonic hindlimb morphogenesis; hair follicle cell proliferation; hair follicle morphogenesis; inner ear receptor cell development; intestinal epithelial cell development; lung development; metal ion binding; miRNA binding; multicellular organism growth; negative regulation of Schwann cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nerve development; neuron projection morphogenesis; olfactory bulb interneuron differentiation; peripheral nervous system myelin formation; positive regulation of Schwann cell differentiation; positive regulation of miRNA metabolic process; positive regulation of myelination; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; pre-miRNA processing; production of siRNA involved in RNA interference; rRNA catabolic process; regulation of Notch signaling pathway; regulation of cell cycle; regulation of enamel mineralization; regulation of neuron differentiation; regulation of oligodendrocyte differentiation; regulation of protein phosphorylation; regulation of viral genome replication; ribonuclease III activity; spinal cord motor neuron differentiation; spindle assembly; spleen development; stem cell maintenance; targeting of mRNA for destruction involved in RNA interference; zygote asymmetric cell division,PF03368;PF00271;PF02170;PF04851;PF00636;,1.00E-60,CHOYP_DICER.2.3,,,,,,,DICER_MOUSE,Mus musculus (Mouse),"anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; chromatin silencing at centromere outer repeat region [GO:1990141]; conversion of ds siRNA to ss siRNA [GO:0036404]; conversion of ds siRNA to ss siRNA involved in RNA interference [GO:0033168]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; olfactory bulb interneuron differentiation [GO:0021889]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of enamel mineralization [GO:0070173]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RNA interference [GO:0016246]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; zygote asymmetric cell division [GO:0010070]" comp148040_c0_seq1,324,55.5556,1.01841942,0,18,,3.00E-13,P96920,Exodeoxyribonuclease V beta chain (EC 3.1.11.5),,GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0005618; GO:0005829; GO:0004519; GO:0008854; GO:0090305; GO:0005886,ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; cell wall; cytosol; endonuclease activity; exodeoxyribonuclease V activity; nucleic acid phosphodiester bond hydrolysis; plasma membrane,,,,,,,,,,EX5B_MYCTU,, comp148042_c0_seq1,318,44.9686,1.00236655,0,22,,1.00E-26,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp148060_c0_seq1,337,36.2018,0.93889716,8,24,,6.00E-15,Q5R573,Rab-like protein 2A,Rab-like protein 2A,GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF00071;,1.00E-27,CHOYP_LOC100371074.1.1,,,,,,,RBL2A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),small GTPase mediated signal transduction [GO:0007264] comp148066_c0_seq1,259,31.6602,0.17196024,3,19,,9.00E-08,Q5SNZ0,Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),GO:0006260; GO:0005794; GO:0031929; GO:0003779; GO:0032148; GO:0016477; GO:0016023; GO:0031410; GO:0005829; GO:0005783; GO:0030027; GO:0030032; GO:0061024; GO:0008017; GO:0035091; GO:0005886; GO:0042803; GO:0006275; GO:0032956; GO:0042127; GO:0010975,DNA replication; Golgi apparatus; TOR signaling cascade; actin binding; activation of protein kinase B activity; cell migration; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; endoplasmic reticulum; lamellipodium; lamellipodium assembly; membrane organization; microtubule binding; phosphatidylinositol binding; plasma membrane; protein homodimerization activity; regulation of DNA replication; regulation of actin cytoskeleton organization; regulation of cell proliferation; regulation of neuron projection development,PF05622;,1.00E-13,CHOYP_GRDN.5.5,,,,,,,GRDN_MOUSE,Mus musculus (Mouse),activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp148070_c0_seq1,271,38.3764,0.60445267,5,11,,3.00E-07,Q0P6H9,Transmembrane protein 62,Transmembrane protein 62,GO:0016021,integral to membrane,PF00149;,,,,,,,,,TMM62_HUMAN,Homo sapiens (Human), comp148071_c0_seq1,315,40.3175,0.24804018,0,21,,2.00E-24,Q28GJ2,Ester hydrolase C11orf54 homolog (EC 3.1.-.-),Ester hydrolase C11orf54 homolog (EC 3.1.-.-),GO:0016787; GO:0046872; GO:0005634,hydrolase activity; metal ion binding; nucleus,PF08925;,,,,,,,,,CK054_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp14807_c0_seq1,406,41.6256,0.62721031,13,0,,6.00E-27,Q91VN0,Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),GO:0044332; GO:0042813; GO:0060612; GO:0060033; GO:0009952; GO:1902262; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042074; GO:0060764; GO:0042632; GO:0008203; GO:0015026; GO:0048596; GO:0042733; GO:0060059; GO:0006897; GO:0005783; GO:0035426; GO:0001702; GO:0016021; GO:0005739; GO:0002076; GO:0005886; GO:0033690; GO:0051091; GO:0045944; GO:0043235; GO:0042981; GO:0046850; GO:0045598; GO:0061178; GO:0030278; GO:0061304; GO:0035019,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; adipose tissue development; anatomical structure regression; anterior/posterior pattern specification; apoptotic process involved in patterning of blood vessels; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cell migration involved in gastrulation; cell-cell signaling involved in mammary gland development; cholesterol homeostasis; cholesterol metabolic process; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; extracellular matrix-cell signaling; gastrulation with mouth forming second; integral to membrane; mitochondrion; osteoblast development; plasma membrane; positive regulation of osteoblast proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of apoptotic process; regulation of bone remodeling; regulation of fat cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of ossification; retinal blood vessel morphogenesis; somatic stem cell maintenance,PF00057;PF00058;,,,,,,,,,LRP5_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp148081_c0_seq1,296,40.2027,0.92603098,23,0,,1.00E-26,O46411,Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II) (Cytosolic IMP/GMP-specific 5'-nucleotidase),Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II) (Cytosolic IMP/GMP-specific 5'-nucleotidase),GO:0008253; GO:0005737; GO:0046872; GO:0000166; GO:0009117,5'-nucleotidase activity; cytoplasm; metal ion binding; nucleotide binding; nucleotide metabolic process,PF05761;,,,,,,,,,5NTC_BOVIN,Bos taurus (Bovine),adenosine metabolic process [GO:0046085]; IMP metabolic process [GO:0046040] comp148093_c0_seq1,329,46.2006,0.47312265,1,22,,4.00E-13,P10040,Protein crumbs (95F),Protein crumbs (95F),GO:0016324; GO:0016327; GO:0005509; GO:0061336; GO:0046664; GO:0045198; GO:0016332; GO:0016334; GO:0016021; GO:0035002; GO:0035090; GO:0061024; GO:0045746; GO:0046621; GO:0048477; GO:0045494; GO:0008284; GO:0042327; GO:0008104; GO:0035330; GO:0045570; GO:0016028; GO:0042052; GO:0007435; GO:0005918; GO:0030507; GO:0035003; GO:0045186; GO:0045218,"apical plasma membrane; apicolateral plasma membrane; calcium ion binding; cell morphogenesis involved in Malpighian tubule morphogenesis; dorsal closure, amnioserosa morphology change; establishment of epithelial cell apical/basal polarity; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of polarity of follicular epithelium; integral to membrane; liquid clearance, open tracheal system; maintenance of apical/basal cell polarity; membrane organization; negative regulation of Notch signaling pathway; negative regulation of organ growth; oogenesis; photoreceptor cell maintenance; positive regulation of cell proliferation; positive regulation of phosphorylation; protein localization; regulation of hippo signaling cascade; regulation of imaginal disc growth; rhabdomere; rhabdomere development; salivary gland morphogenesis; septate junction; spectrin binding; subapical complex; zonula adherens assembly; zonula adherens maintenance",PF00008;PF07645;PF00054;PF02210;,,,,,,,,,CRB_DROME,Drosophila melanogaster (Fruit fly),"adherens junction organization [GO:0034332]; cell-cell junction assembly [GO:0007043]; cell morphogenesis involved in Malpighian tubule morphogenesis [GO:0061336]; centrosome localization [GO:0051642]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor development [GO:0042051]; dorsal closure, amnioserosa morphology change [GO:0046664]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; liquid clearance, open tracheal system [GO:0035002]; maintenance of apical/basal cell polarity [GO:0035090]; Malpighian tubule morphogenesis [GO:0007443]; membrane organization [GO:0061024]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of organ growth [GO:0046621]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nuclear chromosome segregation [GO:0098813]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphorylation [GO:0042327]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of hippo signaling [GO:0035330]; regulation of imaginal disc growth [GO:0045570]; regulation of intracellular protein transport [GO:0033157]; regulation of protein localization [GO:0032880]; rhabdomere development [GO:0042052]; rhabdomere morphogenesis [GO:0061541]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; tube morphogenesis [GO:0035239]; zonula adherens assembly [GO:0045186]; zonula adherens maintenance [GO:0045218]" comp148095_c0_seq1,219,39.726,0.35107115,0,17,,7.00E-09,Q9Z265,Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Checkpoint kinase 2),Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Checkpoint kinase 2),GO:0005524; GO:0006975; GO:0000086; GO:0016605; GO:0051301; GO:0006302; GO:0008630; GO:0046872; GO:0045893; GO:0046777; GO:0042803; GO:0004674; GO:0042176; GO:0010332; GO:0072428; GO:0090307; GO:0006351,"ATP binding; DNA damage induced protein phosphorylation; G2/M transition of mitotic cell cycle; PML body; cell division; double-strand break repair; intrinsic apoptotic signaling pathway in response to DNA damage; metal ion binding; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; regulation of protein catabolic process; response to gamma radiation; signal transduction involved in intra-S DNA damage checkpoint; spindle assembly involved in mitosis; transcription, DNA-dependent",PF00498;PF00069;,2.00E-17,CHOYP_LOC100372241.1.1,,,,,,,CHK2_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; response to doxorubicin [GO:1902520]; response to gamma radiation [GO:0010332]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]; transcription, DNA-templated [GO:0006351]" comp148096_c0_seq1,202,47.0297,0.3618627,4,9,,1.00E-07,Q923L3,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_MOUSE,Mus musculus (Mouse),glucose homeostasis [GO:0042593]; startle response [GO:0001964] comp148127_c0_seq1,235,59.1489,1.0325187,2,13,,1.00E-24,Q6A9R0,Ribosomal RNA small subunit methyltransferase H (EC 2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH),Ribosomal RNA small subunit methyltransferase H (EC 2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH),GO:0005737; GO:0071424; GO:0070475,cytoplasm; rRNA (cytosine-N4-)-methyltransferase activity; rRNA base methylation,PF01795;,,,,,,,,,RSMH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),rRNA base methylation [GO:0070475] comp148138_c0_seq1,402,42.7861,0.38899855,17,5,,,,,,,,,8.00E-13,CHOYP_BRAFLDRAFT_123981.1.1,,,,,,,,, comp148139_c0_seq1,326,47.8528,0.28974223,17,6,,1.00E-44,Q810B6,Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif),Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif),GO:0006897; GO:0010008; GO:0046872,endocytosis; endosome membrane; metal ion binding,PF00023;PF12796;PF00651;PF01363;,9.00E-43,CHOYP_LOC100372945.2.2,,,,,,,ANFY1_MOUSE,Mus musculus (Mouse),"endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" comp148140_c0_seq1,277,43.3213,0.57168783,0,24,,4.00E-10,Q9TTI8,Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R),Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R),GO:0097211; GO:0004968; GO:0016021; GO:0005886,cellular response to gonadotropin-releasing hormone; gonadotropin-releasing hormone receptor activity; integral to membrane; plasma membrane,PF00001;,,,,,,,,,GNRHR_TRIVU,Trichosurus vulpecula (Brush-tailed possum), comp148149_c0_seq1,232,53.0172,1.45154376,1,11,,6.00E-13,A4G7S9,Ribosome maturation factor RimP,Ribosome maturation factor RimP,GO:0005737; GO:0042254,cytoplasm; ribosome biogenesis,PF02576;,,,,,,,,,RIMP_HERAR,Herminiimonas arsenicoxydans,ribosomal small subunit biogenesis [GO:0042274] comp148159_c0_seq1,395,43.5443,0.1620305,10,16,,3.00E-09,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp148187_c0_seq1,284,47.8873,0.61635712,6,11,,2.00E-40,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,1.00E-58,CHOYP_LOC577371.1.2,3.00E-14,ruditapes_c7296,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp148199_c0_seq1,268,44.0299,0.69730234,1,20,,1.00E-06,Q18297,Transient receptor potential cation channel subfamily A member 1 homolog,Transient receptor potential cation channel subfamily A member 1 homolog,GO:0016021; GO:0005216; GO:0043025; GO:0031513; GO:0050896,integral to membrane; ion channel activity; neuronal cell body; nonmotile primary cilium; response to stimulus,PF12796;PF00520;,,,,,,,,,TRPA1_CAEEL,Caenorhabditis elegans,response to stimulus [GO:0050896] comp148212_c0_seq1,348,34.7701,0.57244869,7,15,,4.00E-12,Q9H9S5,Fukutin-related protein (EC 2.-.-.-),Fukutin-related protein (EC 2.-.-.-),GO:0005794; GO:0000139; GO:0016010; GO:0005615; GO:0009101; GO:0016021; GO:0016485; GO:0005791; GO:0042383; GO:0016740,Golgi apparatus; Golgi membrane; dystrophin-associated glycoprotein complex; extracellular space; glycoprotein biosynthetic process; integral to membrane; protein processing; rough endoplasmic reticulum; sarcolemma; transferase activity,PF04991;,,,,,,,,,FKRP_HUMAN,Homo sapiens (Human),protein O-linked mannosylation [GO:0035269]; protein processing [GO:0016485] comp148222_c0_seq1,281,40.2135,0.53108017,11,7,,2.00E-06,Q9JHR7,Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin),Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin),GO:0005524; GO:0050435; GO:0010815; GO:0005576; GO:0004222; GO:0005739; GO:0005886; GO:0006508; GO:0008270,ATP binding; beta-amyloid metabolic process; bradykinin catabolic process; extracellular region; metalloendopeptidase activity; mitochondrion; plasma membrane; proteolysis; zinc ion binding,PF00675;PF05193;PF16187;,,,,,,,,,IDE_MOUSE,Mus musculus (Mouse),beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; peptide catabolic process [GO:0043171]; positive regulation of protein oligomerization [GO:0032461]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992] comp148226_c0_seq1,407,40.2948,0.98864749,7,22,,2.00E-22,Q6DIL6,Protein FAM124A,Protein FAM124A,,,PF15067;,3.00E-31,CHOYP_LOC100378692.1.1,,,,,,,F124A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp148241_c0_seq1,419,43.6754,0.35142443,3,33,,9.00E-28,Q599T9,Myeloid differentiation primary response protein MyD88,Myeloid differentiation primary response protein MyD88,GO:0002755; GO:0005829; GO:0050830; GO:0016064; GO:0006954; GO:0045087; GO:0031663; GO:0044130; GO:0005886; GO:0043123; GO:0046330; GO:0051092; GO:0045080; GO:0032740; GO:0032747; GO:0032755; GO:0050671; GO:0032760; GO:0050727; GO:0002238; GO:0032494; GO:0009615; GO:0045351,MyD88-dependent toll-like receptor signaling pathway; cytosol; defense response to Gram-positive bacterium; immunoglobulin mediated immune response; inflammatory response; innate immune response; lipopolysaccharide-mediated signaling pathway; negative regulation of growth of symbiont in host; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of chemokine biosynthetic process; positive regulation of interleukin-17 production; positive regulation of interleukin-23 production; positive regulation of interleukin-6 production; positive regulation of lymphocyte proliferation; positive regulation of tumor necrosis factor production; regulation of inflammatory response; response to molecule of fungal origin; response to peptidoglycan; response to virus; type I interferon biosynthetic process,PF00531;PF01582;,,,,,,,,,MYD88_BOVIN,Bos taurus (Bovine),defense response to Gram-positive bacterium [GO:0050830]; establishment of endothelial intestinal barrier [GO:0090557]; immunoglobulin mediated immune response [GO:0016064]; induced systemic resistance [GO:0009682]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000338]; regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000341]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil migration [GO:1902622]; response to molecule of fungal origin [GO:0002238]; response to peptidoglycan [GO:0032494]; response to virus [GO:0009615]; type I interferon biosynthetic process [GO:0045351] comp148243_c0_seq1,232,40.9483,0.32910216,5,14,,3.00E-20,Q8NCE2,Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy),Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy),GO:0005829; GO:0035335; GO:0048471; GO:0006661; GO:0004438; GO:0004725; GO:0001726; GO:0044281,cytosol; peptidyl-tyrosine dephosphorylation; perinuclear region of cytoplasm; phosphatidylinositol biosynthetic process; phosphatidylinositol-3-phosphatase activity; protein tyrosine phosphatase activity; ruffle; small molecule metabolic process,,7.00E-17,CHOYP_MTMRE.1.1,,,,,,,MTMRE_HUMAN,Homo sapiens (Human),macroautophagy [GO:0016236]; phosphatidylinositol biosynthetic process [GO:0006661] comp148263_c0_seq1,227,44.0529,0.54808756,7,6,,6.00E-11,Q80TQ5,Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),GO:0007030; GO:0005737; GO:0005543,Golgi organization; cytoplasm; phospholipid binding,PF00169;PF02759;,,,,,,,,,PKHM2_MOUSE,Mus musculus (Mouse),Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880] comp148270_c0_seq1,315,40.3175,0.420217,9,8,,3.00E-08,Q9D845,Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1),Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1),,,,5.00E-27,CHOYP_LOC100892369.1.1,,,,,,,TEX9_MOUSE,Mus musculus (Mouse), comp148276_c0_seq1,236,42.7966,0.74705833,1,12,,,,,,,,,6.00E-11,CHOYP_contig_028547,,,,,,,,, comp148280_c0_seq1,334,47.3054,0.73602147,0,28,,4.00E-12,Q9U637,Pituitary homeobox x (Bicoid type transcription factor Pitx) (BbPtx) (Homeobox protein Ptx) (Paired-like homeodomain transcription factor x),Pituitary homeobox x (Bicoid type transcription factor Pitx) (BbPtx) (Homeobox protein Ptx) (Paired-like homeodomain transcription factor x),GO:0007275; GO:0005634; GO:0043565; GO:0003700,multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;PF03826;,8.00E-18,CHOYP_PITX.1.1,,,,,,,PITX_BRABE,Branchiostoma belcheri (Amphioxus),multicellular organism development [GO:0007275] comp148305_c0_seq1,317,42.5868,0.49313738,2,13,,3.00E-34,Q63615,Vacuolar protein sorting-associated protein 33A (r-vps33a),Vacuolar protein sorting-associated protein 33A (r-vps33a),GO:0031410; GO:0031902; GO:0005765; GO:0015031; GO:0006904,cytoplasmic vesicle; late endosome membrane; lysosomal membrane; protein transport; vesicle docking involved in exocytosis,PF00995;,3.00E-30,CHOYP_VP33A.1.1,,,,,,,VP33A_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp148311_c0_seq1,641,41.3417,0.92860675,12,10,,2.00E-15,P58545,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,,,,,,,,,BTBD3_MOUSE,Mus musculus (Mouse),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813] comp148324_c0_seq1,376,37.766,0.74802116,11,10,,7.00E-14,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp148332_c0_seq1,280,50.3571,0.56562718,8,9,,1.00E-30,Q6AZT7,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0060271; GO:0060027; GO:0090090; GO:0072372; GO:2000095,"Wnt receptor signaling pathway; cilium morphogenesis; convergent extension involved in gastrulation; negative regulation of canonical Wnt receptor signaling pathway; primary cilium; regulation of Wnt receptor signaling pathway, planar cell polarity pathway",PF13374;PF13176;,2.00E-19,CHOYP_NPHP3.1.1,,,,,,,NPHP3_XENLA,Xenopus laevis (African clawed frog),"cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]" comp148338_c0_seq1,367,41.9619,0.68459835,6,6,,2.00E-19,Q5SSL4,Active breakpoint cluster region-related protein,Active breakpoint cluster region-related protein,GO:0030675; GO:0005089; GO:0030036; GO:0007420; GO:0005829; GO:0042472; GO:0035556; GO:0030336; GO:0050728; GO:0043314; GO:0050885; GO:0005543; GO:0005886; GO:0050766; GO:0032496,Rac GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; brain development; cytosol; inner ear morphogenesis; intracellular signal transduction; negative regulation of cell migration; negative regulation of inflammatory response; negative regulation of neutrophil degranulation; neuromuscular process controlling balance; phospholipid binding; plasma membrane; positive regulation of phagocytosis; response to lipopolysaccharide,PF00168;PF00169;PF00620;PF00621;,,,,,,,,,ABR_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; positive regulation of phagocytosis [GO:0050766]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496] comp148342_c0_seq1,266,36.0902,0.1160886,3,14,,4.00E-23,Q8WNU8,Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11),Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11),GO:0005524; GO:0031572; GO:0031573; GO:0007243; GO:0046872; GO:0005730; GO:0004674,ATP binding; G2 DNA damage checkpoint; intra-S DNA damage checkpoint; intracellular protein kinase cascade; metal ion binding; nucleolus; protein serine/threonine kinase activity,PF00069;,6.00E-31,CHOYP_BRAFLDRAFT_121964.1.1,,,,,,,NEK11_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),G2 DNA damage checkpoint [GO:0031572]; intracellular signal transduction [GO:0035556]; intra-S DNA damage checkpoint [GO:0031573]; protein phosphorylation [GO:0006468] comp148362_c0_seq1,265,40.3774,0.74406654,0,21,,4.00E-16,Q9C0D6,FH2 domain-containing protein 1,FH2 domain-containing protein 1,,,PF02181;,2.00E-19,CHOYP_BRAFLDRAFT_122887.1.1,,,,,,,FHDC1_HUMAN,Homo sapiens (Human), comp148363_c0_seq1,546,38.0952,1.36661882,8,19,,4.00E-07,O43511,Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4),Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4),GO:0016324; GO:0031526; GO:0015108; GO:0016021; GO:0015111; GO:0006885; GO:0032880; GO:0008271; GO:0007605; GO:0015116; GO:0008272,apical plasma membrane; brush border membrane; chloride transmembrane transporter activity; integral to membrane; iodide transmembrane transporter activity; regulation of pH; regulation of protein localization; secondary active sulfate transmembrane transporter activity; sensory perception of sound; sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A4_HUMAN,Homo sapiens (Human),bicarbonate transport [GO:0015701]; inorganic anion transport [GO:0015698]; ion transport [GO:0006811]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; regulation of pH [GO:0006885]; regulation of protein localization [GO:0032880]; sensory perception of sound [GO:0007605]; sulfate transport [GO:0008272] comp148370_c0_seq1,223,50.6726,0.44269665,10,7,,4.00E-17,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,6.00E-11,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp148371_c0_seq1,482,42.9461,0.52802851,7,25,,8.00E-16,Q92963,GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1),GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1),GO:0005525; GO:0003924; GO:0007265; GO:0005516; GO:0048011; GO:0005886,GTP binding; GTPase activity; Ras protein signal transduction; calmodulin binding; neurotrophin TRK receptor signaling pathway; plasma membrane,PF00071;,,,,,,,,,RIT1_HUMAN,Homo sapiens (Human),Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] comp148379_c0_seq1,261,40.9962,1.02505417,4,16,,9.00E-13,Q9N658,Zinc finger protein sens (Protein senseless),Zinc finger protein sens (Protein senseless),GO:0007219; GO:0045465; GO:0003705; GO:0007411; GO:0043425; GO:0008407; GO:0042051; GO:0048813; GO:0043066; GO:0000122; GO:0005634; GO:0007422; GO:0008594; GO:0005700; GO:0016360; GO:0043565; GO:0007601; GO:0008270,Notch signaling pathway; R8 cell differentiation; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; axon guidance; bHLH transcription factor binding; chaeta morphogenesis; compound eye photoreceptor development; dendrite morphogenesis; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; peripheral nervous system development; photoreceptor cell morphogenesis; polytene chromosome; sensory organ precursor cell fate determination; sequence-specific DNA binding; visual perception; zinc ion binding,PF00096;PF13912;,,,,,,,,,GFI1_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; chaeta morphogenesis [GO:0008407]; compound eye photoreceptor development [GO:0042051]; dendrite morphogenesis [GO:0048813]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; peripheral nervous system development [GO:0007422]; photoreceptor cell differentiation [GO:0046530]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of rhodopsin gene expression [GO:0045872]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R8 cell differentiation [GO:0045465]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; transcription from RNA polymerase II promoter [GO:0006366]; visual perception [GO:0007601]" comp148384_c0_seq1,373,30.8311,1.841244,0,30,,,,,,,,,,,3.00E-22,ruditapes_c17027,,,,,,, comp148389_c0_seq1,540,38.8889,0.40313104,29,0,,5.00E-42,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,4.00E-43,CHOYP_NEMVEDRAFT_V1G199235.2.15,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp148395_c0_seq1,320,44.0625,0.5812934,1,19,,2.00E-39,Q9Y2I7,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),GO:0000285; GO:0016308; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0045121; GO:0046872; GO:0032288; GO:0048471; GO:0043813; GO:0034504; GO:0042147; GO:0044281,"1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; membrane raft; metal ion binding; myelin assembly; perinuclear region of cytoplasm; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; protein localization to nucleus; retrograde transport, endosome to Golgi; small molecule metabolic process",PF00118;PF00610;PF01363;PF01504;,2.00E-24,CHOYP_FYV1.1.1,,,,,,,FYV1_HUMAN,Homo sapiens (Human),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp148400_c0_seq1,332,42.4699,0.6851914,9,16,,2.00E-09,Q804X6,Coagulation factor IX (EC 3.4.21.22) (Christmas factor) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain],Coagulation factor IX (EC 3.4.21.22) (Christmas factor) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain],GO:0007596; GO:0005509; GO:0005576; GO:0006508; GO:0004252,blood coagulation; calcium ion binding; extracellular region; proteolysis; serine-type endopeptidase activity,PF00008;PF00594;PF00089;,,,,,,,,,FA9_CHICK,Gallus gallus (Chicken),blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] comp148402_c0_seq1,236,65.2542,1.26500205,0,17,,5.00E-46,Q6A6M4,Biotin biosynthesis bifunctional protein BioWF [Includes: 6-carboxyhexanoate--CoA ligase (EC 6.2.1.14) (Pimeloyl-CoA synthase); 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (8-amino-7-ketopelargonate synthase)],Biotin biosynthesis bifunctional protein BioWF [Includes: 6-carboxyhexanoate--CoA ligase (EC 6.2.1.14) (Pimeloyl-CoA synthase); 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (8-amino-7-ketopelargonate synthase)],GO:0042410; GO:0008710; GO:0005524; GO:0009102; GO:0030170,6-carboxyhexanoate-CoA ligase activity; 8-amino-7-oxononanoate synthase activity; ATP binding; biotin biosynthetic process; pyridoxal phosphate binding,PF00155;PF03744;,,,,,,,,,BIOWF_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),biotin biosynthetic process [GO:0009102] comp148403_c0_seq1,344,49.1279,0.59500359,11,14,,1.00E-11,P11717,Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),GO:0009986; GO:0030139; GO:0005768; GO:0001948; GO:0005010; GO:0005887; GO:0005765; GO:0005537; GO:0005641; GO:0051219; GO:0006898; GO:0030140; GO:0005215,cell surface; endocytic vesicle; endosome; glycoprotein binding; insulin-like growth factor-activated receptor activity; integral to plasma membrane; lysosomal membrane; mannose binding; nuclear envelope lumen; phosphoprotein binding; receptor-mediated endocytosis; trans-Golgi network transport vesicle; transporter activity,PF00878;PF00040;,,,,,,,,,MPRI_HUMAN,Homo sapiens (Human),liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] comp148404_c0_seq1,217,40.553,0.67878971,2,9,,2.00E-06,B4F6U4,PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10),PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,PRD10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp148410_c0_seq1,279,42.6523,0.5651745,16,8,,8.00E-14,Q5ZKD7,Putative helicase MOV-10 (EC 3.6.4.13),Putative helicase MOV-10 (EC 3.6.4.13),GO:0005524; GO:0003723; GO:0000932; GO:0004386; GO:0035279,ATP binding; RNA binding; cytoplasmic mRNA processing body; helicase activity; mRNA cleavage involved in gene silencing by miRNA,,,,,,,,,,MOV10_CHICK,Gallus gallus (Chicken),gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279] comp148412_c0_seq1,466,38.1974,0.47315314,18,6,,4.00E-08,Q80V03,Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),GO:0016021; GO:0005739; GO:0004674,integral to membrane; mitochondrion; protein serine/threonine kinase activity,PF03109;,,,,,,,,,ADCK5_MOUSE,Mus musculus (Mouse), comp148415_c0_seq1,285,41.4035,0.65899429,2,19,,5.00E-11,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp148420_c0_seq1,235,39.5745,0.8814352,3,9,,,,,,,,,,,4.00E-24,ruditapes_c14166,,,,,,, comp148422_c0_seq1,248,44.7581,0.81373872,1,13,,6.00E-26,O42602,Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1),Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1),GO:0015056; GO:0051458; GO:0016021; GO:0031226; GO:0010579; GO:2000852,corticotrophin-releasing factor receptor activity; corticotropin secretion; integral to membrane; intrinsic to plasma membrane; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; regulation of corticosterone secretion,PF00002;PF02793;,,,,,,,,,CRFR1_XENLA,Xenopus laevis (African clawed frog),cell surface receptor signaling pathway [GO:0007166]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; corticotropin secretion [GO:0051458]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579]; regulation of corticosterone secretion [GO:2000852] comp148445_c0_seq1,413,47.4576,0.56092043,13,7,,2.00E-22,Q69Z28,A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS16_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] comp148447_c0_seq1,349,42.6934,1.13514445,10,15,,2.00E-47,Q9TTR7,COUP transcription factor 2 (COUP-TF2) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2),COUP transcription factor 2 (COUP-TF2) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2),GO:0009952; GO:0048514; GO:0009566; GO:0030900; GO:0004879; GO:0060173; GO:0001893; GO:0045736; GO:0010596; GO:0001937; GO:0000122; GO:0001764; GO:0005634; GO:0060674; GO:0045893; GO:0009956; GO:0060849; GO:0001972; GO:0043565; GO:0007519; GO:0003707; GO:0060707; GO:0008270,"anterior/posterior pattern specification; blood vessel morphogenesis; fertilization; forebrain development; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; limb development; maternal placenta development; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; negative regulation of transcription from RNA polymerase II promoter; neuron migration; nucleus; placenta blood vessel development; positive regulation of transcription, DNA-dependent; radial pattern formation; regulation of transcription involved in lymphatic endothelial cell fate commitment; retinoic acid binding; sequence-specific DNA binding; skeletal muscle tissue development; steroid hormone receptor activity; trophoblast giant cell differentiation; zinc ion binding",PF00104;PF00105;,2.00E-44,CHOYP_N2F1A.1.1,,,,,,,COT2_BOVIN,Bos taurus (Bovine),"anterior/posterior pattern specification [GO:0009952]; blood vessel morphogenesis [GO:0048514]; fertilization [GO:0009566]; forebrain development [GO:0030900]; limb development [GO:0060173]; maternal placenta development [GO:0001893]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; placenta blood vessel development [GO:0060674]; positive regulation of transcription, DNA-templated [GO:0045893]; radial pattern formation [GO:0009956]; regulation of transcription involved in lymphatic endothelial cell fate commitment [GO:0060849]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]" comp148450_c0_seq1,545,44.7706,0.76583468,10,8,,5.00E-23,Q13393,Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),GO:0005794; GO:0000139; GO:0070290; GO:0007265; GO:0006935; GO:0050830; GO:0005789; GO:0005768; GO:0031902; GO:0016042; GO:0005765; GO:0048471; GO:0006654; GO:0006655; GO:0035091; GO:0004630; GO:0044281,Golgi apparatus; Golgi membrane; NAPE-specific phospholipase D activity; Ras protein signal transduction; chemotaxis; defense response to Gram-positive bacterium; endoplasmic reticulum membrane; endosome; late endosome membrane; lipid catabolic process; lysosomal membrane; perinuclear region of cytoplasm; phosphatidic acid biosynthetic process; phosphatidylglycerol biosynthetic process; phosphatidylinositol binding; phospholipase D activity; small molecule metabolic process,PF00169;PF00614;PF13091;PF00787;,2.00E-21,CHOYP_PLD1.1.1,,,,,,,PLD1_HUMAN,Homo sapiens (Human),cell motility [GO:0048870]; chemotaxis [GO:0006935]; inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of microvillus assembly [GO:0032534]; regulation of phagocytosis [GO:0050764]; small GTPase mediated signal transduction [GO:0007264] comp148451_c0_seq1,213,46.4789,0.26420335,4,15,,2.00E-10,O43149,Zinc finger ZZ-type and EF-hand domain-containing protein 1,Zinc finger ZZ-type and EF-hand domain-containing protein 1,GO:0005509; GO:0008270,calcium ion binding; zinc ion binding,PF03256;PF00569;,,,,,,,,,ZZEF1_HUMAN,Homo sapiens (Human), comp148452_c0_seq1,228,48.2456,0.45437382,7,7,,5.00E-06,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp148460_c0_seq1,274,43.0657,0.8730275,0,20,,6.00E-42,Q9N0N3,Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2),Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2),GO:0000978; GO:0001078; GO:0001077; GO:0060349; GO:0071281; GO:0003682; GO:0048701; GO:0035115; GO:0061029; GO:0042472; GO:0001822; GO:0043066; GO:2000378; GO:0010944; GO:0005634; GO:0021623; GO:0003409; GO:0003404; GO:0060021; GO:0030501; GO:0070172; GO:0007605; GO:0003713; GO:0021559,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; bone morphogenesis; cellular response to iron ion; chromatin binding; embryonic cranial skeleton morphogenesis; embryonic forelimb morphogenesis; eyelid development in camera-type eye; inner ear morphogenesis; kidney development; negative regulation of apoptotic process; negative regulation of reactive oxygen species metabolic process; negative regulation of transcription by competitive promoter binding; nucleus; oculomotor nerve formation; optic cup structural organization; optic vesicle morphogenesis; palate development; positive regulation of bone mineralization; positive regulation of tooth mineralization; sensory perception of sound; transcription coactivator activity; trigeminal nerve development,PF03299;,2.00E-37,CHOYP_TCFAP2B.2.2,,,,,,,AP2A_SHEEP,Ovis aries (Sheep),"bone morphogenesis [GO:0060349]; cellular response to iron ion [GO:0071281]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic forelimb morphogenesis [GO:0035115]; eyelid development in camera-type eye [GO:0061029]; inner ear morphogenesis [GO:0042472]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oculomotor nerve formation [GO:0021623]; optic cup structural organization [GO:0003409]; optic vesicle morphogenesis [GO:0003404]; palate development [GO:0060021]; positive regulation of bone mineralization [GO:0030501]; positive regulation of gene expression [GO:0010628]; positive regulation of tooth mineralization [GO:0070172]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; sensory perception of sound [GO:0007605]; trigeminal nerve development [GO:0021559]" comp14848_c0_seq1,334,44.6108,1.2546929,6,0,,2.00E-33,D8VNS7,Ryncolin-1,Ryncolin-1,GO:0005576,extracellular region,PF01391;PF00147;,,,,,,,,,FCNV1_CERRY,Cerberus rynchops (Dog-faced water snake), comp148506_c0_seq1,352,41.4773,0.40358557,17,0,,2.00E-09,P42337,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)",GO:0016303; GO:0035005; GO:0005943; GO:0005524; GO:0001525; GO:0006006; GO:0044029; GO:0030027; GO:2000811; GO:2000270; GO:0043524; GO:0005942; GO:0046934; GO:0048015; GO:0005886; GO:0033138; GO:0043491; GO:0030295; GO:0006468; GO:0004674; GO:2000653; GO:0040014,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ATP binding; angiogenesis; glucose metabolic process; hypomethylation of CpG island; lamellipodium; negative regulation of anoikis; negative regulation of fibroblast apoptotic process; negative regulation of neuron apoptotic process; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; phosphatidylinositol-mediated signaling; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein kinase B signaling cascade; protein kinase activator activity; protein phosphorylation; protein serine/threonine kinase activity; regulation of genetic imprinting; regulation of multicellular organism growth",PF00454;PF00792;PF02192;PF00794;PF00613;,,,,,,,,,PK3CA_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014] comp148512_c0_seq1,289,38.7543,0.55645054,2,16,,1.00E-38,Q5ZL21,Methylmalonic aciduria and homocystinuria type C protein homolog,Methylmalonic aciduria and homocystinuria type C protein homolog,,,PF16690;,,,,,,,,,MMAC_CHICK,Gallus gallus (Chicken), comp148545_c0_seq1,229,37.9913,0.73172127,8,0,,,,,,,,,2.00E-16,CHOYP_LOC100491753.3.3,,,,,,,,, comp148547_c0_seq1,201,55.7214,0.90440358,0,21,,2.00E-14,P35440,Thrombospondin-2,Thrombospondin-2,GO:0005604; GO:0005509; GO:0007155; GO:0008201; GO:0016525,basement membrane; calcium ion binding; cell adhesion; heparin binding; negative regulation of angiogenesis,PF12947;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525] comp148549_c0_seq1,428,41.8224,0.75000409,10,24,,3.00E-38,P41969,ETS domain-containing protein Elk-1,ETS domain-containing protein Elk-1,GO:0005654; GO:0045944; GO:0043565; GO:0003700; GO:0006351,"nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;,6.00E-59,CHOYP_ISCW_ISCW009238.1.1,,,,,,,ELK1_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]" comp148550_c0_seq1,275,45.0909,0.68638653,4,17,,1.00E-26,Q90578,Vitamin D3 hydroxylase-associated protein (VDHAP),Vitamin D3 hydroxylase-associated protein (VDHAP),GO:0016884; GO:0016811; GO:0005743,"carbon-nitrogen ligase activity, with glutamine as amido-N-donor; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; mitochondrial inner membrane",PF01425;,9.00E-23,CHOYP_LOC100712443.1.1,,,,,,,VDHAP_CHICK,Gallus gallus (Chicken), comp148556_c0_seq1,225,37.7778,0.75334821,2,15,,4.00E-14,Q5R6P6,Glia maturation factor beta (GMF-beta),Glia maturation factor beta (GMF-beta),GO:0005622,intracellular,PF00241;,,,,,,,,,GMFB_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316] comp148559_c0_seq1,318,43.3962,1.14289855,1,22,,5.00E-12,Q684R7,FRAS1-related extracellular matrix protein 1 (Protein QBRICK),FRAS1-related extracellular matrix protein 1 (Protein QBRICK),GO:0005604; GO:0030246; GO:0007154; GO:0007160; GO:0097094; GO:0016021; GO:0046872,basement membrane; carbohydrate binding; cell communication; cell-matrix adhesion; craniofacial suture morphogenesis; integral to membrane; metal ion binding,PF03160;PF00059;,,,,,,,,,FREM1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] comp148562_c0_seq1,528,44.697,0.5740038,20,15,,2.00E-87,P59913,Protein-L-isoaspartate O-methyltransferase domain-containing protein 1,Protein-L-isoaspartate O-methyltransferase domain-containing protein 1,GO:0005737; GO:0004719,cytoplasm; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,,5.00E-61,CHOYP_LOC100642024.2.2,,,,,,,PCMD1_MOUSE,Mus musculus (Mouse), comp148595_c0_seq1,269,84.3866,0.94539122,8,15,,,,,,,,,1.00E-34,CHOYP_RNA45S5.2.4,,,,,,,,, comp148600_c0_seq1,205,44.3902,0.43052226,9,9,,8.00E-10,Q6JAN0,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),GO:0004930; GO:0042462; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; eye photoreceptor cell development; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF03160;,1.00E-31,CHOYP_BRAFLDRAFT_102479.1.1,,,,,,,GPR98_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462] comp148601_c0_seq1,1038,35.0674,0.66262817,68,0,,1.00E-15,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp148607_c0_seq1,256,50.7812,0.43412825,1,11,,6.00E-16,Q8TE57,A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS16_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] comp148617_c0_seq1,364,62.9121,0.89229092,2,16,,6.00E-24,Q9UT61,Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase),Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase),GO:0004559; GO:0030246; GO:0005829; GO:0000329; GO:0006013; GO:0009313; GO:0008270,alpha-mannosidase activity; carbohydrate binding; cytosol; fungal-type vacuole membrane; mannose metabolic process; oligosaccharide catabolic process; zinc ion binding,PF09261;PF01074;PF07748;,,,,,,,,,MAN1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517] comp148619_c0_seq1,228,59.2105,1.05555147,2,9,,3.00E-16,P23314,Extracellular protease (EC 3.4.21.-),Extracellular protease (EC 3.4.21.-),GO:0005576; GO:0006508; GO:0004252,extracellular region; proteolysis; serine-type endopeptidase activity,PF00082;PF04151;,,,,,,,,,EXPR_XANCP,Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25), comp148628_c0_seq1,372,39.2473,0.42028473,5,11,,7.00E-25,Q8CGF5,Transmembrane protein 56,Transmembrane protein 56,GO:0016021,integral to membrane,PF03798;,,,,,,,,,TMM56_MOUSE,Mus musculus (Mouse), comp148631_c0_seq1,278,49.6403,0.58614204,7,10,,4.00E-12,O43900,Prickle-like protein 3 (LIM domain only protein 6) (LMO-6) (Triple LIM domain protein 6),Prickle-like protein 3 (LIM domain only protein 6) (LMO-6) (Triple LIM domain protein 6),GO:0008270,zinc ion binding,PF00412;PF06297;,4.00E-33,CHOYP_LOC100160412.1.2,,,,,,,PRIC3_HUMAN,Homo sapiens (Human), comp148634_c0_seq1,260,43.8462,1.44060573,7,15,,2.00E-10,Q04202,Transposable element Tcb2 transposase,Transposable element Tcb2 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB2_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp148638_c0_seq1,397,45.8438,0.78763641,18,13,,7.00E-50,Q6NRH0,Kelch-like protein 12,Kelch-like protein 12,GO:0048208; GO:0031463; GO:0030134; GO:0016055; GO:0007275; GO:0006513,COPII vesicle coating; Cul3-RING ubiquitin ligase complex; ER to Golgi transport vesicle; Wnt receptor signaling pathway; multicellular organismal development; protein monoubiquitination,PF07707;PF00651;PF01344;,2.00E-33,CHOYP_KLH12.1.3,,,,,,,KLH12_XENLA,Xenopus laevis (African clawed frog),COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; multicellular organism development [GO:0007275]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] comp148641_c0_seq1,276,39.8551,0.56130423,0,15,,4.00E-08,Q9BZA8,Protocadherin-11 Y-linked (Protocadherin-11) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC) (Protocadherin-22),Protocadherin-11 Y-linked (Protocadherin-11) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC) (Protocadherin-22),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF08374;,,,,,,,,,PC11Y_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp148643_c0_seq1,695,47.6259,0.81439396,14,34,,7.00E-18,O62640,Putative inhibitor of apoptosis,Putative inhibitor of apoptosis,GO:0006915; GO:0005737; GO:0070266; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0016567; GO:0042981; GO:0004842; GO:0008270,apoptotic process; cytoplasm; necroptosis; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; protein ubiquitination; regulation of apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,PIAP_PIG,Sus scrofa (Pig),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121] comp148644_c0_seq1,360,45.2778,0.93666779,3,19,,2.00E-41,Q5RCU3,N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54),GO:0070290; GO:0016020; GO:0009395; GO:0008270,NAPE-specific phospholipase D activity; membrane; phospholipid catabolic process; zinc ion binding,PF12706;,1.00E-15,CHOYP_NAPEP.1.1,,,,,,,NAPEP_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),phospholipid catabolic process [GO:0009395] comp148645_c0_seq1,307,46.9055,0.23807016,5,9,,2.00E-13,Q9FGY1,Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55),Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55),GO:0046556; GO:0048046; GO:0005975; GO:0009505; GO:0005578; GO:0010214,alpha-N-arabinofuranosidase activity; apoplast; carbohydrate metabolic process; plant-type cell wall; proteinaceous extracellular matrix; seed coat development,PF14310;PF00933;PF01915;,,,,,,,,,BXL1_ARATH,Arabidopsis thaliana (Mouse-ear cress),arabinan catabolic process [GO:0031222]; seed coat development [GO:0010214]; xylan catabolic process [GO:0045493] comp148650_c0_seq1,225,44.8889,0.8110208,0,18,,,,,,,,,,,6.00E-22,ruditapes_c13249,,,,,,, comp148656_c0_seq1,349,39.5415,0.69922883,9,9,,7.00E-14,A8WGS4,TLC domain-containing protein 2,TLC domain-containing protein 2,GO:0016021,integral to membrane,PF03798;,1.00E-16,CHOYP_SMP_140510.3.3,,,,,,,TLCD2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp148658_c0_seq1,315,41.2698,0.60755239,0,26,,1.00E-13,Q7REH6,Glutathione S-transferase (EC 2.5.1.18),Glutathione S-transferase (EC 2.5.1.18),GO:0004364,glutathione transferase activity,PF14497;PF02798;,,,,,,,,,GST_PLAYO,Plasmodium yoelii yoelii, comp148662_c0_seq1,345,42.6087,0.77032187,7,16,,4.00E-32,Q9UBH6,Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor),Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor),GO:0004930; GO:0005887; GO:0001618,G-protein coupled receptor activity; integral to plasma membrane; virus receptor activity,PF03124;PF03105;,7.00E-32,CHOYP_LOC101159134.1.1,,,,,,,XPR1_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; response to virus [GO:0009615] comp148665_c0_seq1,306,43.1373,0.64632269,13,8,,1.00E-47,Q01887,Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R),Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R),GO:0005524; GO:0016055; GO:0042813; GO:0071679; GO:0022038; GO:0005737; GO:0016021; GO:0050919; GO:0048843; GO:0005634; GO:0005886; GO:0043410; GO:0004672; GO:0048705,ATP binding; Wnt receptor signaling pathway; Wnt-activated receptor activity; commissural neuron axon guidance; corpus callosum development; cytoplasm; integral to membrane; negative chemotaxis; negative regulation of axon extension involved in axon guidance; nucleus; plasma membrane; positive regulation of MAPK cascade; protein kinase activity; skeletal system morphogenesis,PF07714;PF02019;,6.00E-32,CHOYP_LOC100703289.1.1,,,,,,,RYK_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of MAPK cascade [GO:0043410]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] comp148670_c0_seq1,218,36.6972,0.13905054,6,12,,,,,,,,,2.00E-11,CHOYP_LOC100371694.1.1,,,,,,,,, comp148683_c0_seq1,229,46.7249,0.99568998,0,19,,1.00E-09,Q99L04,Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),GO:0005783; GO:0005743; GO:0016491,endoplasmic reticulum; mitochondrial inner membrane; oxidoreductase activity,PF00106;,,,,,,,,,DHRS1_MOUSE,Mus musculus (Mouse), comp148690_c0_seq1,338,46.7456,0.65182432,5,15,,6.00E-31,Q7TS68,Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6),Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6),GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF01189;,2.00E-14,CHOYP_BRAFLDRAFT_116066.1.1,,,,,,,NSUN6_MOUSE,Mus musculus (Mouse),RNA methylation [GO:0001510] comp148696_c0_seq1,300,42.3333,0.37438227,7,17,,6.00E-25,Q1RMK1,Protein FAM92B,Protein FAM92B,,,PF06730;,,,,,,,,,FA92B_BOVIN,Bos taurus (Bovine), comp148700_c0_seq1,656,40.2439,1.02395759,8,36,,5.00E-49,Q96PQ7,Kelch-like protein 5,Kelch-like protein 5,GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF07707;PF00651;PF01344;,,,,,,,,,KLHL5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp148710_c0_seq1,217,46.0829,0.26542771,0,14,,7.00E-10,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp148712_c0_seq1,215,67.907,1.17211838,0,14,,7.00E-22,P45694,Transketolase (TK) (EC 2.2.1.1),Transketolase (TK) (EC 2.2.1.1),GO:0046872; GO:0004802,metal ion binding; transketolase activity,PF02779;PF02780;PF00456;,,,,,,,,,TKT_BACSU,Bacillus subtilis (strain 168),metabolic process [GO:0008152] comp148714_c0_seq1,477,49.2662,0.98051713,6,24,,1.00E-24,Q68SA9,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS7_MOUSE,Mus musculus (Mouse),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp148717_c0_seq1,237,60.7595,1.24056263,0,16,,3.00E-08,Q05491,Protein MutL,Protein MutL,,,PF13941;,,,,,,,,,MUTL_CLOTT,Clostridium tetanomorphum, comp148725_c0_seq1,262,42.7481,1.34571836,0,16,,3.00E-12,B0JZG0,Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2),Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00860;,,,,,,,,,S23A2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp148731_c0_seq1,443,39.7291,0.78595172,6,32,,7.00E-37,A7SG73,Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (Fragment),Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (Fragment),GO:0009435; GO:0004514,NAD biosynthetic process; nicotinate-nucleotide diphosphorylase (carboxylating) activity,PF01729;PF02749;,2.00E-26,CHOYP_BRAFLDRAFT_232705.1.2,,,,,,,NADC_NEMVE,Nematostella vectensis (Starlet sea anemone),NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213] comp148761_c0_seq1,207,40.0966,0.85148186,0,16,,2.00E-12,Q568L5,Alcohol dehydrogenase [NADP(+)] B (EC 1.1.1.2) (Aldehyde reductase-B) (Aldo-keto reductase family 1 member A1-B),Alcohol dehydrogenase [NADP(+)] B (EC 1.1.1.2) (Aldehyde reductase-B) (Aldo-keto reductase family 1 member A1-B),GO:0008106,alcohol dehydrogenase (NADP+) activity,PF00248;,,,,,,,,,A1A1B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp148799_c0_seq1,398,41.4573,0.72545913,17,3,,2.00E-12,P21675,Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250),Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250),GO:0005524; GO:0003677; GO:0006352; GO:0071339; GO:0051123; GO:0070577; GO:0004402; GO:0000080; GO:0019048; GO:0005634; GO:0018105; GO:0018107; GO:0032436; GO:0045944; GO:0060261; GO:0046777; GO:0004674; GO:0000117; GO:0006355; GO:0006974; GO:0043565; GO:0003713; GO:0006368; GO:0005669; GO:0016032,"ATP binding; DNA binding; DNA-dependent transcription, initiation; MLL1 complex; RNA polymerase II transcriptional preinitiation complex assembly; histone acetyl-lysine binding; histone acetyltransferase activity; mitotic G1 phase; modulation by virus of host morphology or physiology; nucleus; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription initiation from RNA polymerase II promoter; protein autophosphorylation; protein serine/threonine kinase activity; regulation of transcription involved in G2/M transition of mitotic cell cycle; regulation of transcription, DNA-dependent; response to DNA damage stimulus; sequence-specific DNA binding; transcription coactivator activity; transcription elongation from RNA polymerase II promoter; transcription factor TFIID complex; viral process",PF00439;PF12157;PF09247;,,,,,,,,,TAF1_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; DNA-templated transcription, initiation [GO:0006352]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp148801_c0_seq1,330,46.9697,0.66756916,7,18,,2.00E-29,P12890,Peptidyl-glycine alpha-amidating monooxygenase B (PAM-B) (Peptide C-terminal alpha-amidating enzyme II) (AE-II) (Peptidyl-glycine alpha-amidating monooxygenase II) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase B (PHM-B) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase B (EC 4.3.2.5) (Peptidylamidoglycolate lyase-B) (PAL-B)],Peptidyl-glycine alpha-amidating monooxygenase B (PAM-B) (Peptide C-terminal alpha-amidating enzyme II) (AE-II) (Peptidyl-glycine alpha-amidating monooxygenase II) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase B (PHM-B) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase B (EC 4.3.2.5) (Peptidylamidoglycolate lyase-B) (PAL-B)],GO:0005507; GO:0016021; GO:0006518; GO:0004598; GO:0004504; GO:0030658,copper ion binding; integral to membrane; peptide metabolic process; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; transport vesicle membrane,PF03712;PF01082;PF01436;,,,,,,,,,AMDB_XENLA,Xenopus laevis (African clawed frog),peptide metabolic process [GO:0006518] comp148812_c0_seq1,708,46.4689,0.57667965,24,7,,7.00E-09,P08F94,Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),GO:0031362; GO:0016324; GO:0016337; GO:0005813; GO:0042384; GO:0005737; GO:0042592; GO:0016021; GO:0001822; GO:0005932; GO:0072686; GO:0051271; GO:0072372; GO:0004872; GO:0010824,anchored to external side of plasma membrane; apical plasma membrane; cell-cell adhesion; centrosome; cilium assembly; cytoplasm; homeostatic process; integral to membrane; kidney development; microtubule basal body; mitotic spindle; negative regulation of cellular component movement; primary cilium; receptor activity; regulation of centrosome duplication,PF10162;PF01833;,,,,,,,,,PKHD1_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337] comp148813_c0_seq1,287,41.8118,0.64071968,8,12,,3.00E-37,Q5M8I4,Protein TSSC1,Protein TSSC1,,,PF00400;,2.00E-37,CHOYP_TSSC1.1.1,,,,,,,TSSC1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp148819_c0_seq1,201,61.194,1.0148321,0,10,,9.00E-39,Q6A6Q4,Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase),GO:0044209; GO:0005524; GO:0004017; GO:0005737,AMP salvage; ATP binding; adenylate kinase activity; cytoplasm,,,,,,,,,,KAD_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),AMP salvage [GO:0044209] comp148821_c0_seq1,411,45.9854,0.79231238,9,18,,2.00E-28,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp148824_c0_seq1,668,42.6647,0.64667422,25,15,,2.00E-65,Q8NFP9,Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B),Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B),GO:0005829; GO:0012505; GO:0005886; GO:0008104; GO:0005802,cytosol; endomembrane system; plasma membrane; protein localization; trans-Golgi network,PF02138;PF06469;PF15787;PF14844;,6.00E-55,CHOYP_LOC100646535.1.1,,,,,,,NBEA_HUMAN,Homo sapiens (Human),protein localization [GO:0008104] comp148830_c0_seq1,267,58.427,1.32151755,0,14,,7.00E-52,Q6A998,Heat-inducible transcription repressor HrcA,Heat-inducible transcription repressor HrcA,GO:0003677; GO:0005622; GO:0006950; GO:0003700; GO:0006351,"DNA binding; intracellular; response to stress; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01628;PF08220;,,,,,,,,,HRCA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp148842_c0_seq1,500,44.8,0.87979279,11,3,,2.00E-12,Q7TT28,RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1),RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1),GO:0004527; GO:0003676; GO:0090305; GO:0005634,exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF15870;,,,8.00E-12,ruditapes2_c1064,,,,,REXO1_MOUSE,Mus musculus (Mouse), comp148846_c0_seq2,504,47.619,0.56126923,2,0,,6.00E-24,Q8IVF5,T-lymphoma invasion and metastasis-inducing protein 2 (TIAM-2) (SIF and TIAM1-like exchange factor),T-lymphoma invasion and metastasis-inducing protein 2 (TIAM-2) (SIF and TIAM1-like exchange factor),GO:0005096; GO:0005089; GO:0097190; GO:0044255; GO:0005829; GO:0030175; GO:0030426; GO:0005085; GO:0030027; GO:0016020; GO:0048011; GO:0005543; GO:0043065; GO:0005057; GO:0035023; GO:0051056; GO:0007264; GO:0044281,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; cellular lipid metabolic process; cytosol; filopodium; growth cone; guanyl-nucleotide exchange factor activity; lamellipodium; membrane; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of apoptotic process; receptor signaling protein activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; small molecule metabolic process,PF00595;PF00169;PF00621;,1.00E-30,CHOYP_AGAP_AGAP006590.1.1,,,,,,,TIAM2_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp148850_c0_seq1,433,48.7298,0.19691575,18,9,,2.00E-62,Q920M9,E3 ubiquitin-protein ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a),E3 ubiquitin-protein ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a),GO:0030877; GO:0007049; GO:0030154; GO:0005829; GO:0005769; GO:0007275; GO:0051402; GO:0005634; GO:0005886; GO:0043065; GO:2001244; GO:0043161; GO:0031648; GO:0042787; GO:0007283; GO:0004842; GO:0008270,beta-catenin destruction complex; cell cycle; cell differentiation; cytosol; early endosome; multicellular organismal development; neuron apoptotic process; nucleus; plasma membrane; positive regulation of apoptotic process; positive regulation of intrinsic apoptotic signaling pathway; proteasomal ubiquitin-dependent protein catabolic process; protein destabilization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; spermatogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF03145;,4.00E-61,CHOYP_LOC100555807.1.1,,,,,,,SIAH1_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; neuron apoptotic process [GO:0051402]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp148852_c0_seq1,299,44.8161,0.33534916,1,10,,8.00E-17,Q54KD0,TPR repeat-containing protein DDB_G0287407,TPR repeat-containing protein DDB_G0287407,GO:0017111; GO:0000166,nucleoside-triphosphatase activity; nucleotide binding,PF13271;,5.00E-26,CHOYP_BRAFLDRAFT_122847.2.2,,,,,,,Y7407_DICDI,Dictyostelium discoideum (Slime mold), comp148858_c0_seq1,264,47.3485,0.40707189,7,7,,2.00E-10,Q9DFQ7,60S ribosomal protein L24,60S ribosomal protein L24,GO:0005840,ribosome,PF01246;,2.00E-55,CHOYP_RL13.1.4,4.00E-31,ruditapes_c34139,,,,,RL24_GILMI,Gillichthys mirabilis (Long-jawed mudsucker), comp148861_c0_seq1,452,42.2566,0.6465776,15,7,,5.00E-19,A6NI28,Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42),Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42),GO:0005096; GO:0005622; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; intracellular; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00169;PF00620;PF14604;,,,,,,,,,RHG42_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp148872_c0_seq1,201,66.1692,1.14204545,0,17,,7.00E-35,B9MEU8,1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS),1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS),GO:0052865; GO:0008661; GO:0000287; GO:0016114; GO:0009228; GO:0030976,1-deoxy-D-xylulose 5-phosphate biosynthetic process; 1-deoxy-D-xylulose-5-phosphate synthase activity; magnesium ion binding; terpenoid biosynthetic process; thiamine biosynthetic process; thiamine pyrophosphate binding,PF13292;PF02779;PF02780;,,,,,,,,,DXS_ACIET,Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)),1-deoxy-D-xylulose 5-phosphate biosynthetic process [GO:0052865]; terpenoid biosynthetic process [GO:0016114]; thiamine biosynthetic process [GO:0009228] comp148879_c0_seq1,360,42.5,0.98803362,16,7,,3.00E-08,Q9QYE3,B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9),B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9),GO:0030183; GO:0030217; GO:0005737; GO:0046872; GO:0010629; GO:0016604; GO:0003676; GO:0016925; GO:0006355; GO:0003714; GO:0006351,"B cell differentiation; T cell differentiation; cytoplasm; metal ion binding; negative regulation of gene expression; nuclear body; nucleic acid binding; protein sumoylation; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",,5.00E-27,CHOYP_YTDC2.1.1,,,,,,,BC11A_MOUSE,Mus musculus (Mouse),B cell differentiation [GO:0030183]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of neuron projection development [GO:0010976]; protein sumoylation [GO:0016925]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366] comp148901_c0_seq1,359,44.2897,0.70381778,20,0,,1.00E-43,Q32PW3,Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),GO:0008237; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"metallopeptidase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01433;,1.00E-22,CHOYP_LOC100706922.1.1,,,,,,,TAF2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp148912_c0_seq1,357,44.2577,1.03668767,0,23,,2.00E-29,Q9UKN7,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,3.00E-56,CHOYP_MYO15.1.1,,,,,,,MYO15_HUMAN,Homo sapiens (Human),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp148922_c0_seq1,229,49.7817,0.78475442,5,6,,,,,,,,,2.00E-18,CHOYP_LOC593338.2.2,,,,,,,,, comp148937_c0_seq1,221,44.7964,0.94069723,3,11,,7.00E-19,Q8IWF2,FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation),GO:0030433; GO:0005788; GO:0050660; GO:0016491,ER-associated protein catabolic process; endoplasmic reticulum lumen; flavin adenine dinucleotide binding; oxidoreductase activity,,,,,,,,,,FXRD2_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114] comp148938_c0_seq1,265,41.5094,0.36932147,4,14,,2.00E-06,Q12770,Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),GO:0012507; GO:0000139; GO:0032933; GO:0007568; GO:0008203; GO:0005783; GO:0005789; GO:0016021; GO:0045541; GO:0045716; GO:0043234; GO:0042304; GO:0001666; GO:0032868; GO:0044281; GO:0051082,ER to Golgi transport vesicle membrane; Golgi membrane; SREBP signaling pathway; aging; cholesterol metabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; negative regulation of cholesterol biosynthetic process; positive regulation of low-density lipoprotein particle receptor biosynthetic process; protein complex; regulation of fatty acid biosynthetic process; response to hypoxia; response to insulin stimulus; small molecule metabolic process; unfolded protein binding,PF12349;PF00400;,,,,,,,,,SCAP_HUMAN,Homo sapiens (Human),aging [GO:0007568]; cholesterol metabolic process [GO:0008203]; negative regulation of cholesterol biosynthetic process [GO:0045541]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933] comp148939_c0_seq1,308,44.8052,2.17553211,0,16,,,,,,,,,9.00E-11,CHOYP_contig_027445,,,,,,,,, comp148953_c0_seq1,201,50.7463,0.38967014,2,8,,6.00E-11,O08653,Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog),Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005634; GO:0030529,"ATP binding; RNA binding; chromosome, telomeric region; nucleus; ribonucleoprotein complex",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_RAT,Rattus norvegicus (Rat),RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722] comp148961_c0_seq1,233,42.4893,0.78196929,3,7,,1.00E-13,Q1EG27,Myosin-IIIb (EC 2.7.11.1),Myosin-IIIb (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0032433; GO:0000146; GO:0016459; GO:0018105; GO:0018107; GO:0001917; GO:0001750; GO:0051491; GO:0046777; GO:0004674; GO:0050896; GO:0032426; GO:0007601,ATP binding; cytoplasm; filopodium tip; microfilament motor activity; myosin complex; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; photoreceptor inner segment; photoreceptor outer segment; positive regulation of filopodium assembly; protein autophosphorylation; protein serine/threonine kinase activity; response to stimulus; stereocilium bundle tip; visual perception,PF00612;PF00063;PF00069;,2.00E-18,CHOYP_MYO3AL.1.1,,,,,,,MYO3B_MOUSE,Mus musculus (Mouse),peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp148970_c0_seq1,543,41.4365,0.69167431,18,8,,3.00E-22,Q01887,Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R),Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R),GO:0005524; GO:0016055; GO:0042813; GO:0071679; GO:0022038; GO:0005737; GO:0016021; GO:0050919; GO:0048843; GO:0005634; GO:0005886; GO:0043410; GO:0004672; GO:0048705,ATP binding; Wnt receptor signaling pathway; Wnt-activated receptor activity; commissural neuron axon guidance; corpus callosum development; cytoplasm; integral to membrane; negative chemotaxis; negative regulation of axon extension involved in axon guidance; nucleus; plasma membrane; positive regulation of MAPK cascade; protein kinase activity; skeletal system morphogenesis,PF07714;PF02019;,,,9.00E-18,ruditapes_c15777,,,,,RYK_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axonogenesis [GO:0007409]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of MAPK cascade [GO:0043410]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] comp148998_c0_seq1,255,40.7843,0.40829974,0,20,,6.00E-32,Q6ZN54,Differentially expressed in FDCP 8 homolog (DEF-8),Differentially expressed in FDCP 8 homolog (DEF-8),GO:0035556; GO:0008270,intracellular signal transduction; zinc ion binding,PF00130;PF13901;,2.00E-31,CHOYP_DFI8A.1.1,,,,,,,DEFI8_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp149002_c0_seq1,230,39.5652,0.8343811,3,11,,,,,,,,,2.00E-11,CHOYP_contig_041133,4.00E-11,ruditapes_lrc31621,,,,,,, comp149007_c0_seq1,205,44.3902,0.7217389,0,17,,5.00E-07,P70117,Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Pancreas cancer-associated protein 4),Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Pancreas cancer-associated protein 4),GO:0007155; GO:0016020; GO:0005578; GO:0005044,cell adhesion; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00530;,,,,,,,,,LG3BP_MESAU,Mesocricetus auratus (Golden hamster),cell adhesion [GO:0007155] comp149012_c0_seq1,336,38.6905,0.81697693,3,19,,1.00E-54,F6PTN1,Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A),Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A),GO:0016055; GO:0017147; GO:0060322; GO:0031301; GO:0005887; GO:0046872; GO:0004222; GO:0030178; GO:0018158; GO:0006508,Wnt receptor signaling pathway; Wnt-protein binding; head development; integral to organelle membrane; integral to plasma membrane; metal ion binding; metalloendopeptidase activity; negative regulation of Wnt receptor signaling pathway; protein oxidation; proteolysis,PF01963;,,,,,,,,,TIKI1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),head development [GO:0060322]; negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508]; Wnt signaling pathway [GO:0016055] comp149025_c0_seq1,604,36.2583,0.71573629,4,36,,8.00E-26,O88561,Long-chain fatty acid transport protein 3 (FATP-3) (Fatty acid transport protein 3) (EC 6.2.1.-) (Solute carrier family 27 member 3),Long-chain fatty acid transport protein 3 (FATP-3) (Fatty acid transport protein 3) (EC 6.2.1.-) (Solute carrier family 27 member 3),GO:0006637; GO:0004321; GO:0016021; GO:0004467; GO:0005739; GO:0000166,acyl-CoA metabolic process; fatty-acyl-CoA synthase activity; integral to membrane; long-chain fatty acid-CoA ligase activity; mitochondrion; nucleotide binding,PF00501;PF13193;,,,,,,,,,S27A3_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676] comp149036_c0_seq1,804,43.1592,0.46043406,35,8,,2.00E-39,O76924,Protein ariadne-2 (Ari-2),Protein ariadne-2 (Ari-2),GO:0003676; GO:0005634; GO:0008270,nucleic acid binding; nucleus; zinc ion binding,PF01485;,1.00E-64,CHOYP_ARI2.1.1,,,,,,,ARI2_DROME,Drosophila melanogaster (Fruit fly),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp149037_c0_seq1,204,67.6471,0.96021043,0,15,,4.00E-08,Q9KU08,Exopolyphosphatase (ExopolyPase) (EC 3.6.1.11) (Metaphosphatase),Exopolyphosphatase (ExopolyPase) (EC 3.6.1.11) (Metaphosphatase),GO:0004309; GO:0000287; GO:0006793; GO:0006798,exopolyphosphatase activity; magnesium ion binding; phosphorus metabolic process; polyphosphate catabolic process,PF02541;,,,,,,,,,PPX_VIBCH,Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961),phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798] comp149039_c0_seq1,387,37.9845,0.28740933,14,12,,3.00E-45,Q5ZL98,DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A),DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A),GO:0003677; GO:0003899; GO:0005634; GO:0032549; GO:0006351; GO:0008270,"DNA binding; DNA-directed RNA polymerase activity; nucleus; ribonucleoside binding; transcription, DNA-dependent; zinc ion binding",PF04997;PF00623;PF04983;PF05000;PF04998;,,,,,,,,,RPC1_CHICK,Gallus gallus (Chicken),transcription from RNA polymerase III promoter [GO:0006383] comp149044_c0_seq1,341,45.7478,0.52037641,7,10,,4.00E-12,Q9TS33,Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),GO:0005509; GO:0006874; GO:0071318; GO:0071313; GO:0071277; GO:0071286; GO:0016021; GO:0006936; GO:0051289; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; cellular response to ATP; cellular response to caffeine; cellular response to calcium ion; cellular response to magnesium ion; integral to membrane; muscle contraction; protein homotetramerization; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,,,,,,,,,RYR3_RABIT,Oryctolagus cuniculus (Rabbit),calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; muscle contraction [GO:0006936]; protein homotetramerization [GO:0051289] comp149045_c0_seq1,244,59.4262,1.26872096,0,12,,2.00E-55,Q6A760,Non-canonical purine NTP pyrophosphatase (EC 3.6.1.19) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase),Non-canonical purine NTP pyrophosphatase (EC 3.6.1.19) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase),GO:0046872; GO:0009143; GO:0017111; GO:0047429; GO:0000166; GO:0006163,metal ion binding; nucleoside triphosphate catabolic process; nucleoside-triphosphatase activity; nucleoside-triphosphate diphosphatase activity; nucleotide binding; purine nucleotide metabolic process,PF01725;,,,,,,,,,NTPA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide metabolic process [GO:0006163] comp149064_c0_seq1,214,43.9252,0.1950156,7,6,,9.00E-17,Q68CP4,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0005975; GO:0006027; GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0044281; GO:0016746,"carbohydrate metabolic process; glycosaminoglycan catabolic process; heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; small molecule metabolic process; transferase activity, transferring acyl groups",PF07786;,,,,,,,,,HGNAT_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp149071_c0_seq1,259,38.2239,0.53192282,2,14,,7.00E-19,Q9HBH5,Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2),Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2) (Short chain dehydrogenase/reductase family 7C member 4),GO:0005783; GO:0005765; GO:0005739; GO:0016491,endoplasmic reticulum; lysosomal membrane; mitochondrion; oxidoreductase activity,PF00106;,,,,,,,,,RDH14_HUMAN,Homo sapiens (Human),osteoblast differentiation [GO:0001649] comp149072_c0_seq1,203,46.798,0.6885413,2,10,,3.00E-10,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp149073_c0_seq1,211,65.4028,0.84623749,0,18,,1.00E-36,Q655S1,"ATP-dependent zinc metalloprotease FTSH 2, chloroplastic (OsFTSH2) (EC 3.4.24.-)","ATP-dependent zinc metalloprotease FTSH 2, chloroplastic (OsFTSH2) (EC 3.4.24.-)",GO:0005524; GO:0009535; GO:0016021; GO:0046872; GO:0004222; GO:0017111; GO:0006508,ATP binding; chloroplast thylakoid membrane; integral to membrane; metal ion binding; metalloendopeptidase activity; nucleoside-triphosphatase activity; proteolysis,PF00004;PF01434;,,,,,,,,,FTSH2_ORYSJ,Oryza sativa subsp. japonica (Rice),photoinhibition [GO:0010205]; photosystem II repair [GO:0010206]; proteolysis [GO:0006508]; PSII associated light-harvesting complex II catabolic process [GO:0010304]; thylakoid membrane organization [GO:0010027] comp149078_c0_seq1,322,39.441,0.5607693,4,16,,4.00E-13,A7MBI1,Zinc finger protein ZFP69 (Zinc finger protein 642),Zinc finger protein ZFP69 (Zinc finger protein 642),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;PF13912;,,,,,,,,,ZN642_BOVIN,Bos taurus (Bovine),"transcription, DNA-templated [GO:0006351]" comp149090_c0_seq1,354,46.6102,0.38671333,2,25,,2.00E-27,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp149091_c0_seq1,259,65.251,0.87765021,0,15,,3.00E-07,P95596,Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes),Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes),GO:0045454; GO:0005737; GO:0004148; GO:0050660; GO:0006096,cell redox homeostasis; cytoplasm; dihydrolipoyl dehydrogenase activity; flavin adenine dinucleotide binding; glycolysis,PF07992;PF02852;,,,,,,,,,DLDH_RHOCA,Rhodobacter capsulatus (Rhodopseudomonas capsulata),cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096] comp149105_c0_seq1,270,41.8519,0.25630869,10,5,,9.00E-14,Q5REW9,Ankyrin repeat domain-containing protein 27,Ankyrin repeat domain-containing protein 27,GO:0005096; GO:0005737; GO:0043547,GTPase activator activity; cytoplasm; positive regulation of GTPase activity,PF12796;PF02204;,2.00E-12,CHOYP_ANKRD27.1.1,,,,,,,ANR27_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp149121_c0_seq1,276,48.1884,0.95915387,5,13,,2.00E-08,Q5UAW9,Probable G-protein coupled receptor 157,Probable G-protein coupled receptor 157,GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00002;,,,,,,,,,GP157_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166] comp149125_c0_seq1,237,45.9916,0.64152086,5,8,,1.00E-34,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,5.00E-19,CHOYP_MRP1.5.10,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp149131_c0_seq1,296,46.9595,0.62421898,3,17,,7.00E-08,P18715,Gastrula zinc finger protein XlCGF26.1 (Fragment),Gastrula zinc finger protein XlCGF26.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG26_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp149140_c0_seq1,218,45.4128,1.18233385,3,14,,2.00E-10,Q9Y2C9,Toll-like receptor 6 (CD antigen CD286),Toll-like receptor 6 (CD antigen CD286),GO:0002755; GO:0042088; GO:0035355; GO:0007250; GO:0071726; GO:0042742; GO:0042496; GO:0042498; GO:0006954; GO:0045087; GO:0005887; GO:0071723; GO:0030670; GO:0043123; GO:0043507; GO:0045410; GO:0004872; GO:0050707; GO:0034134; GO:0034142; GO:0034150; GO:0038123; GO:0038124; GO:0004888,MyD88-dependent toll-like receptor signaling pathway; T-helper 1 type immune response; Toll-like receptor 2-Toll-like receptor 6 protein complex; activation of NF-kappaB-inducing kinase activity; cellular response to diacyl bacterial lipopeptide; defense response to bacterium; detection of diacyl bacterial lipopeptide; diacyl lipopeptide binding; inflammatory response; innate immune response; integral to plasma membrane; lipopeptide binding; phagocytic vesicle membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of interleukin-6 biosynthetic process; receptor activity; regulation of cytokine secretion; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 6 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway; transmembrane signaling receptor activity,PF13855;PF01463;PF01582;,,,,,,,,,TLR6_HUMAN,Homo sapiens (Human),activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; defense response to bacterium [GO:0042742]; detection of diacyl bacterial lipopeptide [GO:0042496]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; regulation of cytokine secretion [GO:0050707]; signal transduction [GO:0007165]; T-helper 1 type immune response [GO:0042088]; toll-like receptor 6 signaling pathway [GO:0034150]; toll-like receptor signaling pathway [GO:0002224]; toll-like receptor TLR6:TLR2 signaling pathway [GO:0038124] comp149154_c0_seq1,249,37.3494,0.36197495,4,7,,,,,,,,,,,8.00E-21,ruditapes2_c1194,,,,,,, comp149168_c0_seq1,262,37.4046,0.22507816,2,14,,2.00E-06,Q16706,"Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0006491; GO:0030246; GO:0016799; GO:0001701; GO:0016021; GO:0001889; GO:0048286; GO:0006013; GO:0004572; GO:0007005; GO:0043687; GO:0018279; GO:0007585; GO:0007033; GO:0008270,"Golgi membrane; N-glycan processing; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; in utero embryonic development; integral to membrane; liver development; lung alveolus development; mannose metabolic process; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; mitochondrion organization; post-translational protein modification; protein N-linked glycosylation via asparagine; respiratory gaseous exchange; vacuole organization; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A1_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033] comp149169_c0_seq1,297,44.7811,0.55288196,7,11,,9.00E-24,Q7PXG4,SAGA-associated factor 11 homolog,SAGA-associated factor 11 homolog,GO:0016568; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08209;,1.00E-21,CHOYP_AT7L3.2.2,,,,,,,SGF11_ANOGA,Anopheles gambiae (African malaria mosquito),"histone deubiquitination [GO:0016578]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp149195_c0_seq1,277,36.1011,0.47705469,0,19,,2.00E-33,Q12965,Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E),Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E),GO:0005524; GO:0042623; GO:0051015; GO:0030048; GO:0005912; GO:0005516; GO:0005911; GO:0030136; GO:0005737; GO:0006897; GO:0032836; GO:0003094; GO:0072015; GO:0001701; GO:0000146; GO:0016459; GO:0035091; GO:0048008; GO:0035166; GO:0001570,"ATP binding; ATPase activity, coupled; actin filament binding; actin filament-based movement; adherens junction; calmodulin binding; cell-cell junction; clathrin-coated vesicle; cytoplasm; endocytosis; glomerular basement membrane development; glomerular filtration; glomerular visceral epithelial cell development; in utero embryonic development; microfilament motor activity; myosin complex; phosphatidylinositol binding; platelet-derived growth factor receptor signaling pathway; post-embryonic hemopoiesis; vasculogenesis",PF00063;PF06017;PF00018;,7.00E-18,CHOYP_MYO1E.1.1,,,,,,,MYO1E_HUMAN,Homo sapiens (Human),actin filament-based movement [GO:0030048]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015]; in utero embryonic development [GO:0001701]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570] comp149199_c0_seq1,239,41.0042,0.70441485,1,15,,2.00E-11,Q8T882,Tauropine dehydrogenase (TaDH) (EC 1.5.1.23) (NAD: tauropine oxidoreductase),Tauropine dehydrogenase (TaDH) (EC 1.5.1.23) (NAD: tauropine oxidoreductase),GO:0051287; GO:0005737; GO:0046168; GO:0016616; GO:0050325,"NAD binding; cytoplasm; glycerol-3-phosphate catabolic process; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; tauropine dehydrogenase activity",PF02317;,,,,,,,,,TADH_ARAIR,Arabella iricolor (Opal worm), comp149207_c0_seq1,358,46.648,0.73480105,15,0,,3.00E-32,P26432,Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3),Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3),GO:0030165; GO:0016324; GO:0031526; GO:0009986; GO:0016021; GO:0006885; GO:0015385,PDZ domain binding; apical plasma membrane; brush border membrane; cell surface; integral to membrane; regulation of pH; sodium:hydrogen antiporter activity,PF00999;,6.00E-64,CHOYP_AAEL_AAEL001503.1.1,,,,,,,SL9A3_RABIT,Oryctolagus cuniculus (Rabbit),regulation of pH [GO:0006885] comp149214_c0_seq1,230,54.7826,0.81565224,0,11,,1.00E-18,P96218,Glutamate synthase [NADPH] large chain (EC 1.4.1.13) (Glutamate synthase subunit alpha) (GLTS alpha chain),Glutamate synthase [NADPH] large chain (EC 1.4.1.13) (Glutamate synthase subunit alpha) (GLTS alpha chain),GO:0051538; GO:0097054; GO:0005829; GO:0004355; GO:0006541; GO:0040007; GO:0046872; GO:0005886,"3 iron, 4 sulfur cluster binding; L-glutamate biosynthetic process; cytosol; glutamate synthase (NADPH) activity; glutamine metabolic process; growth; metal ion binding; plasma membrane",PF00310;PF04898;PF01645;PF01493;,,,,,,,,,GLTB_MYCTU,Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv),ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; growth [GO:0040007]; L-glutamate biosynthetic process [GO:0097054] comp149215_c0_seq1,263,43.7262,0.64000925,4,11,,1.00E-31,O94762,"ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)","ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)",GO:0005524; GO:0008026; GO:0003678; GO:0006310; GO:0006281; GO:0006260; GO:0016591; GO:0000993; GO:0051301; GO:0051304; GO:0005737; GO:0007067; GO:0034244; GO:0031965; GO:0003676; GO:0005730,"ATP binding; ATP-dependent helicase activity; DNA helicase activity; DNA recombination; DNA repair; DNA replication; DNA-directed RNA polymerase II, holoenzyme; RNA polymerase II core binding; cell division; chromosome separation; cytoplasm; mitosis; negative regulation of transcription elongation from RNA polymerase II promoter; nuclear membrane; nucleic acid binding; nucleolus",PF00270;PF00271;PF06959;PF16124;,6.00E-12,CHOYP_RECQL5.1.1,,,,,,,RECQ5_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244] comp149222_c0_seq1,440,40,0.35191032,7,14,,1.00E-60,P79110,"Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)","Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)",GO:0016021; GO:0005743; GO:0055085,integral to membrane; mitochondrial inner membrane; transmembrane transport,PF00153;,9.00E-76,CHOYP_LOC660776.1.1,,,,,,,TXTP_BOVIN,Bos taurus (Bovine),translation [GO:0006412]; transmembrane transport [GO:0055085] comp149249_c0_seq1,248,49.1935,1.14531083,2,20,,2.00E-23,P12527,Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34),Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34),GO:0002526; GO:0004051; GO:0019369; GO:0005829; GO:0030425; GO:0005506; GO:0019370; GO:0019372; GO:0005641; GO:0016363; GO:0031965; GO:0045907; GO:0055093; GO:0007584; GO:0042383; GO:0019233,acute inflammatory response; arachidonate 5-lipoxygenase activity; arachidonic acid metabolic process; cytosol; dendrite; iron ion binding; leukotriene biosynthetic process; lipoxygenase pathway; nuclear envelope lumen; nuclear matrix; nuclear membrane; positive regulation of vasoconstriction; response to hyperoxia; response to nutrient; sarcolemma; sensory perception of pain,PF00305;PF01477;,,,,,,,,,LOX5_RAT,Rattus norvegicus (Rat),acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; leukotriene biosynthetic process [GO:0019370]; lipoxygenase pathway [GO:0019372]; positive regulation of vasoconstriction [GO:0045907]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233] comp149255_c0_seq1,309,61.165,1.07688264,4,16,,3.00E-21,P11880,UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10) (D-alanyl-D-alanine-adding enzyme) (UDP-MurNAc-pentapeptide synthetase),UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10) (D-alanyl-D-alanine-adding enzyme) (UDP-MurNAc-pentapeptide synthetase),GO:0005524; GO:0047480; GO:0008766; GO:0007049; GO:0051301; GO:0005737; GO:0009252; GO:0008360,"ATP binding; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; cell cycle; cell division; cytoplasm; peptidoglycan biosynthetic process; regulation of cell shape",PF01225;PF02875;PF08245;,,,,,,,,,MURF_ECOLI,Escherichia coli (strain K12),cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp149261_c0_seq1,240,42.0833,1.32628089,4,13,,5.00E-07,Q866F1,"Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)","Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)",GO:0032580; GO:0008107; GO:0016021; GO:0006486,Golgi cisterna membrane; galactoside 2-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation,PF01531;,,,,,,,,,FUT1_SAISC,Saimiri sciureus (Common squirrel monkey),protein glycosylation [GO:0006486] comp149271_c0_seq1,205,51.7073,0.44143908,2,16,,2.00E-25,Q9UKP4,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,2.00E-22,CHOYP_BRAFLDRAFT_85817.1.1,,,,,,,ATS7_HUMAN,Homo sapiens (Human),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; protein O-linked fucosylation [GO:0036066]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp149277_c0_seq1,599,43.4057,0.64655353,17,17,,1.00E-18,Q5ZM13,Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A),Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A),GO:0005737; GO:0016020,cytoplasm; membrane,PF09790;,,,,,,,,,HYCCI_CHICK,Gallus gallus (Chicken),establishment of protein localization to plasma membrane [GO:0090002]; myelination [GO:0042552]; phosphatidylinositol phosphorylation [GO:0046854] comp149278_c0_seq1,655,37.4046,0.48770051,4,33,,1.00E-84,Q8IZT8,Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (3-OST-5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5),Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (3-OST-5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5),GO:0050656; GO:0000139; GO:0008467; GO:0005975; GO:0006024; GO:0015015; GO:0016021; GO:0050819; GO:0006477; GO:0046596,"3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; carbohydrate metabolic process; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; integral to membrane; negative regulation of coagulation; protein sulfation; regulation of viral entry into host cell",PF00685;,5.00E-43,CHOYP_LOC101165781.1.1,,,,,,,HS3S5_HUMAN,Homo sapiens (Human),"glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]" comp149283_c0_seq1,366,62.2951,1.07443021,2,18,,9.00E-06,C5D8Q2,"Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH))","Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH))",GO:0044205; GO:0006207; GO:0005737; GO:0004158; GO:0004589,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; cytoplasm; dihydroorotate oxidase activity; orotate reductase (NADH) activity,PF01180;,,,,,,,,,PYRDB_GEOSW,Geobacillus sp. (strain WCH70),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205] comp149290_c0_seq1,386,46.6321,0.66897597,9,9,,7.00E-32,Q8CBE3,WD repeat-containing protein 37,WD repeat-containing protein 37,,,PF00400;,,,,,,,,,WDR37_MOUSE,Mus musculus (Mouse),maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] comp149291_c0_seq1,582,44.3299,0.49719932,17,7,,2.00E-43,Q0KK59,Protein unc-79 homolog,Protein unc-79 homolog,GO:0048149; GO:0016021; GO:0035264,behavioral response to ethanol; integral to membrane; multicellular organism growth,,7.00E-79,CHOYP_UNC79.2.4,,,,,,,UNC79_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] comp149297_c0_seq1,268,39.9254,0.56513392,5,16,,4.00E-07,A2AJ77,PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),GO:0003677; GO:0046872; GO:0008168; GO:0022008; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; neurogenesis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD12_MOUSE,Mus musculus (Mouse),"neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp149324_c0_seq1,382,39.7906,0.54646353,4,9,,6.00E-31,Q9D2V8,Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein),Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein),GO:0006915; GO:0016021; GO:0055085; GO:0005215,apoptotic process; integral to membrane; transmembrane transport; transporter activity,PF07690;,3.00E-36,CHOYP_LOC592950.1.1,,,,,,,MFS10_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; sodium-independent organic anion transport [GO:0043252]; tetracycline transport [GO:0015904]; transmembrane transport [GO:0055085] comp149329_c0_seq1,202,49.505,0.65380024,0,13,,2.00E-29,Q05586,"Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)","Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)",GO:0004972; GO:0017146; GO:0008344; GO:0005262; GO:0005509; GO:0055074; GO:0005516; GO:0006812; GO:0030054; GO:0009986; GO:0006874; GO:0071287; GO:0021987; GO:0001661; GO:0032590; GO:0043197; GO:0060076; GO:0005234; GO:0016595; GO:0016594; GO:0035235; GO:0007616; GO:0060179; GO:0043524; GO:0042165; GO:0008355; GO:0021586; GO:0043065; GO:2000463; GO:0045944; GO:0014069; GO:0045211; GO:0060134; GO:0018964; GO:0050770; GO:0048814; GO:0048169; GO:0043576; GO:0051963; GO:0007585; GO:0001975; GO:0051592; GO:0045471; GO:0060992; GO:0043278; GO:0048511; GO:0019233; GO:0035176; GO:0001967; GO:0043083; GO:0035249; GO:0008021; GO:0043195; GO:0008542; GO:0022843,"N-methyl-D-aspartate selective glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor complex; adult locomotory behavior; calcium channel activity; calcium ion binding; calcium ion homeostasis; calmodulin binding; cation transport; cell junction; cell surface; cellular calcium ion homeostasis; cellular response to manganese ion; cerebral cortex development; conditioned taste aversion; dendrite membrane; dendritic spine; excitatory synapse; extracellular-glutamate-gated ion channel activity; glutamate binding; glycine binding; ionotropic glutamate receptor signaling pathway; long-term memory; male mating behavior; negative regulation of neuron apoptotic process; neurotransmitter binding; olfactory learning; pons maturation; positive regulation of apoptotic process; positive regulation of excitatory postsynaptic membrane potential; positive regulation of transcription from RNA polymerase II promoter; postsynaptic density; postsynaptic membrane; prepulse inhibition; propylene metabolic process; regulation of axonogenesis; regulation of dendrite morphogenesis; regulation of long-term neuronal synaptic plasticity; regulation of respiratory gaseous exchange; regulation of synapse assembly; respiratory gaseous exchange; response to amphetamine; response to calcium ion; response to ethanol; response to fungicide; response to morphine; rhythmic process; sensory perception of pain; social behavior; suckling behavior; synaptic cleft; synaptic transmission, glutamatergic; synaptic vesicle; terminal bouton; visual learning; voltage-gated cation channel activity",PF01094;PF10562;PF00060;PF10613;,7.00E-35,CHOYP_LOC100533321.1.1,,,,,,,NMDZ1_HUMAN,Homo sapiens (Human),"adult locomotory behavior [GO:0008344]; calcium ion homeostasis [GO:0055074]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular response to manganese ion [GO:0071287]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; ephrin receptor signaling pathway [GO:0048013]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term memory [GO:0007616]; male mating behavior [GO:0060179]; MAPK cascade [GO:0000165]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory learning [GO:0008355]; pons maturation [GO:0021586]; positive regulation of apoptotic process [GO:0043065]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prepulse inhibition [GO:0060134]; propylene metabolic process [GO:0018964]; protein tetramerization [GO:0051262]; regulation of axonogenesis [GO:0050770]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of synapse assembly [GO:0051963]; respiratory gaseous exchange [GO:0007585]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to morphine [GO:0043278]; rhythmic process [GO:0048511]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; suckling behavior [GO:0001967]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542]" comp149339_c0_seq1,210,45.7143,1.19263574,0,10,,4.00E-22,P16052,Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein),Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein),GO:0005525; GO:0003924; GO:0071880; GO:0046872; GO:0005886; GO:0032320; GO:0030819; GO:0043950; GO:0004871,GTP binding; GTPase activity; adenylate cyclase-activating adrenergic receptor signaling pathway; metal ion binding; plasma membrane; positive regulation of Ras GTPase activity; positive regulation of cAMP biosynthetic process; positive regulation of cAMP-mediated signaling; signal transducer activity,PF00503;,,,,,,,,,GNAS_CRILO,Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of GTPase activity [GO:0043547] comp149340_c0_seq1,362,48.895,0.2828593,12,7,,4.00E-17,Q9IBG7,Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_XENLA,Xenopus laevis (African clawed frog), comp149345_c0_seq1,335,44.4776,0.49612845,10,7,,4.00E-17,A1L0Y2,Neuralized-like protein 4,Neuralized-like protein 4,GO:0005814,centriole,PF07177;,4.00E-16,CHOYP_NEUL4.2.2,,,,,,,NEUL4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp149352_c0_seq1,313,43.4505,0.4838262,5,11,,3.00E-17,Q5RDF5,Juxtaposed with another zinc finger protein 1,Juxtaposed with another zinc finger protein 1,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,JAZF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"lipid metabolic process [GO:0006629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp149378_c0_seq1,217,42.8571,1.11226852,2,8,,2.00E-31,O35655,Serine/threonine-protein phosphatase with EF-hands 1 (PPEF-1) (EC 3.1.3.16) (DRES10) (Protein phosphatase with EF calcium-binding domain) (PPEF),Serine/threonine-protein phosphatase with EF-hands 1 (PPEF-1) (EC 3.1.3.16) (DRES10) (Protein phosphatase with EF calcium-binding domain) (PPEF),GO:0005509; GO:0050906; GO:0005506; GO:0030145; GO:0004722,calcium ion binding; detection of stimulus involved in sensory perception; iron ion binding; manganese ion binding; protein serine/threonine phosphatase activity,PF13499;PF00149;PF08321;,,,,,,,,,PPE1_MOUSE,Mus musculus (Mouse),detection of stimulus involved in sensory perception [GO:0050906] comp149389_c0_seq1,216,49.0741,0.54154458,7,4,,3.00E-09,Q96JB1,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,8.00E-22,CHOYP_DNAH5.1.2,,,,,,,DYH8_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp149398_c0_seq1,215,60.9302,0.9661226,0,18,,7.00E-20,Q9LTV6,"Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)","Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)",GO:0008670; GO:0006631; GO:0005777; GO:0005774,"2,4-dienoyl-CoA reductase (NADPH) activity; fatty acid metabolic process; peroxisome; vacuolar membrane",,,,,,,,,,DECR2_ARATH,Arabidopsis thaliana (Mouse-ear cress),fatty acid metabolic process [GO:0006631] comp149400_c0_seq1,382,44.2408,0.59355155,16,6,,9.00E-50,Q13574,Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta),Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta),GO:0005524; GO:0003951; GO:0016477; GO:0005737; GO:0004143; GO:0004857; GO:0035556; GO:0030027; GO:0001727; GO:0046872; GO:0031571; GO:0046580; GO:0045930; GO:0005634; GO:0005886; GO:0030168; GO:0008022; GO:0007205,ATP binding; NAD+ kinase activity; cell migration; cytoplasm; diacylglycerol kinase activity; enzyme inhibitor activity; intracellular signal transduction; lamellipodium; lipid kinase activity; metal ion binding; mitotic G1 DNA damage checkpoint; negative regulation of Ras protein signal transduction; negative regulation of mitotic cell cycle; nucleus; plasma membrane; platelet activation; protein C-terminus binding; protein kinase C-activating G-protein coupled receptor signaling pathway,PF12796;PF00130;PF00609;PF00781;,9.00E-50,CHOYP_DGKZA.2.2,,,,,,,DGKZ_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of mitotic cell cycle [GO:0045930]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205] comp149409_c0_seq1,379,43.5356,0.39117919,6,10,,5.00E-34,Q5XF89,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,3.00E-17,CHOYP_LOC660831.1.1,,,,,,,AT133_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp149424_c0_seq1,482,36.3071,0.77280333,7,23,,,,,,,,,1.00E-17,CHOYP_LOC586954.1.1,,,,,,,,, comp149425_c0_seq1,210,44.2857,0.7814992,0,14,,3.00E-14,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp149427_c0_seq1,307,42.3453,0.58541842,5,7,,1.00E-20,A1YPR0,Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C),Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C),GO:0046872; GO:0003676,metal ion binding; nucleic acid binding,PF00651;,,,,,,,,,ZBT7C_HUMAN,Homo sapiens (Human),positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025] comp149428_c0_seq2,258,46.5116,0.2877821,3,6,,5.00E-26,Q15678,Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez),Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez),GO:0005737; GO:0005856; GO:0001946; GO:0008285; GO:0005634; GO:0004725; GO:0046825; GO:0006355; GO:0003712; GO:0006351,"cytoplasm; cytoskeleton; lymphangiogenesis; negative regulation of cell proliferation; nucleus; protein tyrosine phosphatase activity; regulation of protein export from nucleus; regulation of transcription, DNA-dependent; transcription cofactor activity; transcription, DNA-dependent",PF09380;PF00373;PF09379;PF00102;,1.00E-33,CHOYP_PTPN14.1.1,,,,,,,PTN14_HUMAN,Homo sapiens (Human),"lymphangiogenesis [GO:0001946]; negative regulation of cell proliferation [GO:0008285]; protein dephosphorylation [GO:0006470]; regulation of protein export from nucleus [GO:0046825]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp149438_c0_seq1,315,36.8254,0.8579272,5,15,,2.00E-12,A0L9N3,Protein translocase subunit SecA 3,Protein translocase subunit SecA 3,GO:0005524; GO:0005737; GO:0065002; GO:0005886; GO:0017038; GO:0006605,ATP binding; cytoplasm; intracellular protein transmembrane transport; plasma membrane; protein import; protein targeting,PF07517;PF01043;,,,,,,,,,SECA3_MAGSM,Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1),intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605] comp149439_c0_seq1,202,42.0792,1.03573967,1,8,,6.00E-09,A7E3W2,Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein),Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein),GO:0007155; GO:0070062; GO:0016020; GO:0005578; GO:0005044,cell adhesion; extracellular vesicular exosome; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00530;,,,,,,,,,LG3BP_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155] comp149459_c0_seq1,418,40.6699,0.4064602,9,9,,5.00E-28,Q9NXK6,Membrane progestin receptor gamma (mPR gamma) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V),Membrane progestin receptor gamma (mPR gamma) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V),GO:0030154; GO:0016021; GO:0007275; GO:0048477; GO:0005496,cell differentiation; integral to membrane; multicellular organismal development; oogenesis; steroid binding,PF03006;,,,,,,,,,MPRG_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; oogenesis [GO:0048477]; response to steroid hormone [GO:0048545] comp149474_c0_seq1,240,30.8333,0.36935507,1,9,,6.00E-14,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp149476_c0_seq1,224,61.6071,0.9654773,0,12,,7.00E-07,P35684,60S ribosomal protein L3,60S ribosomal protein L3,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00297;,,,,,,,,,RL3_ORYSJ,Oryza sativa subsp. japonica (Rice),ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp149478_c0_seq1,280,47.5,0.8900566,3,7,,1.00E-15,Q7ZWN4,Midnolin-A (Midbrain nucleolar protein A),Midnolin-A (Midbrain nucleolar protein A),GO:0005730,nucleolus,PF00240;,,,,,,,,,MIDNA_XENLA,Xenopus laevis (African clawed frog), comp149479_c0_seq1,289,39.7924,0.61404244,0,24,,2.00E-11,Q80TS3,Latrophilin-3 (Lectomedin-3),Adhesion G protein-coupled receptor L3 (Latrophilin-3) (Lectomedin-3),GO:0004930; GO:0030246; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; carbohydrate binding; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,,,,,,,,,LPHN3_MOUSE,Mus musculus (Mouse),cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; locomotion involved in locomotory behavior [GO:0031987]; neuron migration [GO:0001764]; positive regulation of synapse assembly [GO:0051965]; response to cocaine [GO:0042220]; synapse assembly [GO:0007416] comp14949_c0_seq1,207,38.1643,0.53334578,2,0,,9.00E-10,A6H730,Prostatic acid phosphatase (EC 3.1.3.2),Prostatic acid phosphatase (EC 3.1.3.2),GO:0003993; GO:0005576,acid phosphatase activity; extracellular region,PF00328;,,,,,,,,,PPAP_BOVIN,Bos taurus (Bovine),adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772] comp149512_c0_seq1,202,49.0099,0.08285917,1,11,,3.00E-22,A9L8T6,Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1),Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1),GO:0000139; GO:0016477; GO:0008283; GO:0005789; GO:0016021; GO:0050709; GO:0015031; GO:0006508; GO:0042058; GO:0061136; GO:0004252,Golgi membrane; cell migration; cell proliferation; endoplasmic reticulum membrane; integral to membrane; negative regulation of protein secretion; protein transport; proteolysis; regulation of epidermal growth factor receptor signaling pathway; regulation of proteasomal protein catabolic process; serine-type endopeptidase activity,PF01694;PF12595;,3.00E-20,CHOYP_RHDF1.1.3,,,,,,,RHDF1_PAPAN,Papio anubis (Olive baboon),cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136] comp149514_c0_seq1,223,48.4305,0.4634576,4,9,,1.00E-08,B4F785,"Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)","Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)",GO:0030054; GO:0005578; GO:0045202,cell junction; proteinaceous extracellular matrix; synapse,PF00008;PF00041;PF00054;,,,,,,,,,EGFLA_RAT,Rattus norvegicus (Rat), comp149518_c0_seq1,214,45.7944,0.64400208,2,9,,1.00E-24,A7HHN3,Urease accessory protein UreG,Urease accessory protein UreG,GO:0005524; GO:0005525; GO:0003924; GO:0005737; GO:0016530; GO:0016151,ATP binding; GTP binding; GTPase activity; cytoplasm; metallochaperone activity; nickel cation binding,PF02492;,,,,,,,,,UREG_ANADF,Anaeromyxobacter sp. (strain Fw109-5),nitrogen compound metabolic process [GO:0006807] comp149520_c0_seq1,213,47.8873,0.84922507,0,13,,6.00E-14,Q80XJ3,Tetratricopeptide repeat protein 28 (TPR repeat protein 28),Tetratricopeptide repeat protein 28 (TPR repeat protein 28),GO:0051301; GO:0005813; GO:0005737; GO:0030496; GO:0007067; GO:1990023; GO:0097431; GO:0007346,cell division; centrosome; cytoplasm; midbody; mitosis; mitotic spindle midzone; mitotic spindle pole; regulation of mitotic cell cycle,PF12770;PF13176;,,,,,,,,,TTC28_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp149521_c0_seq1,533,44.4653,0.54426517,7,20,,2.00E-86,Q5F452,Myotubularin-related protein 8 (EC 3.1.3.-),Myotubularin-related protein 8 (EC 3.1.3.-),GO:0005635; GO:0035335; GO:0004725,nuclear envelope; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF06602;,5.00E-93,CHOYP_ISCW_ISCW018501.2.2,,,,,,,MTMR8_CHICK,Gallus gallus (Chicken),phosphatidylinositol dephosphorylation [GO:0046856]; regulation of autophagy [GO:0010506] comp149522_c0_seq1,290,42.4138,0.46685047,3,10,,6.00E-33,P14925,Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)],Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)],GO:0031418; GO:0005509; GO:0009986; GO:0007417; GO:0005507; GO:0005615; GO:0007507; GO:0016021; GO:0007595; GO:0060173; GO:0001676; GO:0060135; GO:0043005; GO:0042476; GO:0022602; GO:0001519; GO:0004598; GO:0004504; GO:0043204; GO:0048471; GO:0005886; GO:0018032; GO:0051260; GO:0032956; GO:0050708; GO:0006357; GO:0046688; GO:0042493; GO:0032355; GO:0051384; GO:0001666; GO:0009268; GO:0030667; GO:0009404; GO:0005802; GO:0030658; GO:0008270,L-ascorbic acid binding; calcium ion binding; cell surface; central nervous system development; copper ion binding; extracellular space; heart development; integral to membrane; lactation; limb development; long-chain fatty acid metabolic process; maternal process involved in female pregnancy; neuron projection; odontogenesis; ovulation cycle process; peptide amidation; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; perikaryon; perinuclear region of cytoplasm; plasma membrane; protein amidation; protein homooligomerization; regulation of actin cytoskeleton organization; regulation of protein secretion; regulation of transcription from RNA polymerase II promoter; response to copper ion; response to drug; response to estradiol stimulus; response to glucocorticoid stimulus; response to hypoxia; response to pH; secretory granule membrane; toxin metabolic process; trans-Golgi network; transport vesicle membrane; zinc ion binding,PF03712;PF01082;PF01436;,1.00E-27,CHOYP_PAM.1.1,,,,,,,AMD_RAT,Rattus norvegicus (Rat),central nervous system development [GO:0007417]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404] comp149525_c0_seq1,442,41.629,0.15768946,18,7,,2.00E-09,P70428,Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog),Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog),GO:0000139; GO:0050509; GO:0030154; GO:0005789; GO:0050508; GO:0006024; GO:0042328; GO:0015012; GO:0015014; GO:0016021; GO:0031227; GO:0001707; GO:0001503; GO:0006486; GO:0042803,"Golgi membrane; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; cell differentiation; endoplasmic reticulum membrane; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; glycosaminoglycan biosynthetic process; heparan sulfate N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; mesoderm formation; ossification; protein glycosylation; protein homodimerization activity",PF03016;PF09258;,,,,,,,,,EXT2_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; cellular polysaccharide biosynthetic process [GO:0033692]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; mesoderm formation [GO:0001707]; ossification [GO:0001503]; protein glycosylation [GO:0006486]" comp149526_c0_seq1,428,46.9626,0.42475479,20,0,,,,,,,,,4.00E-23,CHOYP_LOC100892044.1.2,,,,,,,,, comp149542_c0_seq1,208,50.9615,0.30290555,0,20,,,,,,,,,2.00E-11,CHOYP_LOC100887947.1.2,,,,,,,,, comp149543_c0_seq1,309,57.6052,1.3512962,10,5,,4.00E-25,P18775,Dimethyl sulfoxide reductase DmsA (DMSO reductase) (DMSOR) (Me2SO reductase) (EC 1.8.5.3),Dimethyl sulfoxide reductase DmsA (DMSO reductase) (DMSOR) (Me2SO reductase) (EC 1.8.5.3),GO:0051539; GO:0009061; GO:0009389; GO:0009390; GO:0009055; GO:0005506; GO:0016020; GO:0030151; GO:0016491; GO:0005886,"4 iron, 4 sulfur cluster binding; anaerobic respiration; dimethyl sulfoxide reductase activity; dimethyl sulfoxide reductase complex; electron carrier activity; iron ion binding; membrane; molybdenum ion binding; oxidoreductase activity; plasma membrane",PF04879;PF00384;PF01568;,,,,,,,,,DMSA_ECOLI,Escherichia coli (strain K12),anaerobic respiration [GO:0009061] comp149570_c0_seq1,288,46.5278,0.58581787,3,9,,5.00E-34,Q6GLR7,Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),GO:0030054; GO:0030659; GO:0006887; GO:0046872; GO:0005543; GO:0015031; GO:0045202,cell junction; cytoplasmic vesicle membrane; exocytosis; metal ion binding; phospholipid binding; protein transport; synapse,PF06292;PF00169;,2.00E-44,CHOYP_LOC100372028.1.1,,,,,,,CAPS1_XENLA,Xenopus laevis (African clawed frog),dense core granule exocytosis [GO:1990504]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079] comp149573_c0_seq1,222,59.009,0.94227264,0,13,,3.00E-11,P46336,Protein IolS (EC 1.1.1.-) (AKR11A) (Vegetative protein 147) (VEG147),Protein IolS (EC 1.1.1.-) (AKR11A) (Vegetative protein 147) (VEG147),GO:0016491,oxidoreductase activity,PF00248;,,,,,,,,,IOLS_BACSU,Bacillus subtilis (strain 168), comp149587_c0_seq1,264,32.9545,0.1432453,4,2,,8.00E-11,Q9GPF0,AP-4 complex subunit mu (AP-4 adapter complex mu4 subunit) (Adapter-related protein complex 4 subunit mu) (Clathrin-adaptor medium chain Apm4) (Mu4-adaptin),AP-4 complex subunit mu (AP-4 adaptor complex mu4 subunit) (Adaptor-related protein complex 4 subunit mu) (Clathrin-adaptor medium chain Apm4) (Mu4-adaptin),GO:0030124; GO:0030131; GO:0030659; GO:0006886; GO:0016192,AP-4 adaptor complex; clathrin adaptor complex; cytoplasmic vesicle membrane; intracellular protein transport; vesicle-mediated transport,PF00928;,,,,,,,,,AP4M_DICDI,Dictyostelium discoideum (Slime mold),intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp149591_c0_seq1,323,37.4613,0.90757172,8,8,,9.00E-24,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,7.00E-25,CHOYP_LOC100056407.1.1,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp149593_c0_seq1,257,44.358,0.87458951,5,9,,1.00E-14,Q1ENI8,Peroxidasin homolog (EC 1.11.1.7),Peroxidasin homolog (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF01462;,,,,,,,,,PXDN_CAEEL,Caenorhabditis elegans,hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp149597_c0_seq1,243,48.1481,0.57244371,7,3,,5.00E-21,Q3SXM5,Inactive hydroxysteroid dehydrogenase-like protein 1,Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3),GO:0005739; GO:0055114; GO:0016491,mitochondrion; oxidation-reduction process; oxidoreductase activity,PF00106;,2.00E-17,CHOYP_LOC100371253.1.1,,,,,,,HSDL1_HUMAN,Homo sapiens (Human), comp149601_c0_seq1,211,44.5498,0.5760999,0,13,,5.00E-06,Q8CDF7,Exonuclease 3'-5' domain-containing protein 1 (Exonuclease 3'-5' domain-like-containing protein 1),piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1) (mExd1),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;,,,,,,,,,EXD1_MOUSE,Mus musculus (Mouse),gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587] comp149606_c0_seq1,305,46.5574,0.79928526,12,5,,2.00E-27,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,1.00E-52,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp149622_c0_seq1,282,46.4539,0.9964914,3,14,,6.00E-33,P83053,"Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)","Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)",GO:0004556; GO:0005975; GO:0005615; GO:0046872,alpha-amylase activity; carbohydrate metabolic process; extracellular space; metal ion binding,PF00128;PF02806;,2.00E-25,CHOYP_AMY.3.3,,,,,,,AMYP_STRCA,Struthio camelus (Common ostrich),carbohydrate metabolic process [GO:0005975] comp149629_c0_seq1,263,38.0228,0.31731228,1,10,,2.00E-06,Q9H246,Uncharacterized protein C1orf21 (Cell proliferation-inducing gene 13 protein),Uncharacterized protein C1orf21 (Cell proliferation-inducing gene 13 protein),,,PF15389;,,,,,,,,,CA021_HUMAN,Homo sapiens (Human), comp149630_c0_seq1,227,59.4714,1.10389466,0,11,,2.00E-14,O06434,Biopolymer transport protein ExbD,Biopolymer transport protein ExbD,GO:0016021; GO:0005886; GO:0015031; GO:0005215,integral to membrane; plasma membrane; protein transport; transporter activity,PF02472;,,,,,,,,,EXBD_NEIGO,Neisseria gonorrhoeae,protein transport [GO:0015031] comp149638_c0_seq1,236,39.4068,0.67076676,8,5,,1.00E-06,Q63633,Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Furosemide-sensitive K-Cl cotransporter) (K-Cl cotransporter 2) (rKCC2) (Neuronal K-Cl cotransporter),Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Furosemide-sensitive K-Cl cotransporter) (K-Cl cotransporter 2) (rKCC2) (Neuronal K-Cl cotransporter),GO:0051739; GO:0015696; GO:0032590; GO:0016021; GO:0051452; GO:0043204; GO:0006813; GO:0015379,ammonia transmembrane transporter activity; ammonium transport; dendrite membrane; integral to membrane; intracellular pH reduction; perikaryon; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,2.00E-16,CHOYP_DWIL_GK15715.1.1,,,,,,,S12A5_RAT,Rattus norvegicus (Rat),ammonium transport [GO:0015696]; chemical synaptic transmission [GO:0007268]; chloride transport [GO:0006821]; dendritic spine development [GO:0060996]; intracellular pH reduction [GO:0051452]; potassium ion transport [GO:0006813] comp149662_c0_seq1,234,59.8291,1.20120779,0,13,,9.00E-06,Q58288,Uncharacterized lipoprotein MJ0878,Uncharacterized lipoprotein MJ0878,GO:0005886,plasma membrane,PF01497;,,,,,,,,,Y878_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),transport [GO:0006810] comp149669_c0_seq1,273,46.5201,0.47712083,2,9,,,,,,,,,2.00E-17,CHOYP_LOC100493179.5.15,,,,,,,,, comp149679_c0_seq1,248,39.9194,0.72384898,3,12,,7.00E-11,Q9NZN5,Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF),Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF),GO:0001664; GO:0007186; GO:0005096; GO:0005089; GO:0097190; GO:0007411; GO:0005829; GO:0016020; GO:0048011; GO:0005543; GO:0043547; GO:0043065; GO:0035023; GO:0051056; GO:0007264; GO:0038032,G-protein coupled receptor binding; G-protein coupled receptor signaling pathway; GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; axon guidance; cytosol; membrane; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of GTPase activity; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; termination of G-protein coupled receptor signaling pathway,PF00595;PF09128;PF00621;,,,,,,,,,ARHGC_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp149689_c0_seq1,245,48.1633,0.99654438,5,5,,1.00E-28,Q15811,Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),GO:0005089; GO:0097190; GO:0005509; GO:0030054; GO:0005905; GO:0005829; GO:0030139; GO:0005085; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0048011; GO:0005543; GO:0005886; GO:0043065; GO:0051897; GO:0032947; GO:0035023; GO:0051056; GO:0007264; GO:0045202; GO:0048488,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; calcium ion binding; cell junction; coated pit; cytosol; endocytic vesicle; guanyl-nucleotide exchange factor activity; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; positive regulation of apoptotic process; positive regulation of protein kinase B signaling cascade; protein complex scaffold; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; synapse; synaptic vesicle endocytosis,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,2.00E-23,CHOYP_BRAFLDRAFT_83720.1.1,,,,,,,ITSN1_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488] comp149690_c0_seq1,228,43.4211,0.28388976,5,9,,3.00E-38,P41233,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0071222; GO:0071300; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0007040; GO:0045121; GO:0002790; GO:0045335; GO:0006911; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lysosome organization; membrane raft; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,,,,,,,,,ABCA1_MOUSE,Mus musculus (Mouse),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp149709_c0_seq1,269,48.3271,0.57857942,4,13,,5.00E-23,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,,,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp149714_c0_seq1,316,43.6709,1.27176105,1,17,,2.00E-16,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp149719_c0_seq1,313,40.8946,0.8795608,6,10,,2.00E-16,Q22460,Beta carbonic anhydrase 1 (EC 4.2.1.1),Beta carbonic anhydrase 1 (EC 4.2.1.1),GO:0004089; GO:0008270,carbonate dehydratase activity; zinc ion binding,PF00484;,,,,,,,,,BCA1_CAEEL,Caenorhabditis elegans, comp149738_c0_seq1,227,46.2555,0.75276589,2,8,,8.00E-14,Q864R9,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp149742_c0_seq1,347,42.6513,0.44517914,20,4,,2.00E-13,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp149745_c0_seq1,296,40.8784,0.84184634,0,13,,5.00E-17,Q68CR1,Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3),Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3),GO:0016021,integral to membrane,PF08238;,3.00E-16,CHOYP_BRAFLDRAFT_130493.1.1,,,,,,,SE1L3_HUMAN,Homo sapiens (Human), comp149749_c0_seq1,295,41.6949,0.48658093,1,16,,5.00E-23,Q9JLY7,Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6),Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6),GO:0017017; GO:0005737; GO:0005634; GO:0035335; GO:0004725; GO:0008138,MAP kinase tyrosine/serine/threonine phosphatase activity; cytoplasm; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,,,,,,,,,DUS14_MOUSE,Mus musculus (Mouse),peptidyl-tyrosine dephosphorylation [GO:0035335] comp149757_c0_seq1,223,54.2601,0.9323162,2,8,,3.00E-13,P44023,Uncharacterized protein HI_0594,Uncharacterized protein HI_0594,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF03606;,,,,,,,,,Y594_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),anion transmembrane transport [GO:0098656] comp149761_c0_seq1,314,32.4841,0.24561653,3,16,,1.00E-07,Q17QL9,Transmembrane protein 184C (Transmembrane protein 34),Transmembrane protein 184C (Transmembrane protein 34),GO:0016021,integral to membrane,PF03619;,,,,,,,,,T184C_BOVIN,Bos taurus (Bovine),transport [GO:0006810] comp149775_c0_seq1,202,37.1287,0.29125534,2,10,,1.00E-07,Q4G0N4,"NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)","NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)",GO:0005524; GO:0019674; GO:0003951; GO:0006741; GO:0005739; GO:0042803,ATP binding; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; mitochondrion; protein homodimerization activity,PF01513;,,,,,,,,,NAKD1_HUMAN,Homo sapiens (Human),NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741] comp149792_c0_seq1,317,38.8013,0.84083333,4,16,,1.00E-11,Q9LZG0,Adenosine kinase 2 (AK 2) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase 2),Adenosine kinase 2 (AK 2) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase 2),GO:0044209; GO:0005524; GO:0004001; GO:0006169; GO:0005507; GO:0005829; GO:0019048; GO:0016773; GO:0005886,"AMP salvage; ATP binding; adenosine kinase activity; adenosine salvage; copper ion binding; cytosol; modulation by virus of host morphology or physiology; phosphotransferase activity, alcohol group as acceptor; plasma membrane",PF00294;,,,,,,,,,ADK2_ARATH,Arabidopsis thaliana (Mouse-ear cress),adenosine salvage [GO:0006169]; AMP salvage [GO:0044209]; viral process [GO:0016032] comp149805_c0_seq1,254,42.9134,0.45309871,0,17,,2.00E-39,Q8BHD0,Ras-related protein Rab-39A (Rab-39),Ras-related protein Rab-39A (Rab-39),GO:0005525; GO:0045335; GO:0030670; GO:0090383; GO:0090385; GO:0005886; GO:0015031; GO:0007264,GTP binding; phagocytic vesicle; phagocytic vesicle membrane; phagosome acidification; phagosome-lysosome fusion; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,4.00E-26,CHOYP_LOC100651946.1.1,,,,,,,RB39A_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp149826_c0_seq1,399,41.3534,0.83908229,10,9,,3.00E-07,A6QPT7,Endoplasmic reticulum aminopeptidase 2 (EC 3.4.11.-),Endoplasmic reticulum aminopeptidase 2 (EC 3.4.11.-),GO:0004177; GO:0005789; GO:0016021; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; endoplasmic reticulum membrane; integral to membrane; metallopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,ERAP2_BOVIN,Bos taurus (Bovine),adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217] comp149828_c0_seq1,232,55.6034,0.67701016,0,13,,7.00E-09,Q9SIW5,40S ribosomal protein S25-1,40S ribosomal protein S25-1,GO:0005840,ribosome,PF03297;,,,,,,,,,RS251_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp149871_c0_seq1,265,45.283,0.23443342,8,8,,2.00E-17,Q9VCU9,Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-),Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-),GO:0005524; GO:0016442; GO:0016443; GO:0005737; GO:0048813; GO:0003725; GO:0033227; GO:0042078; GO:0030727; GO:0007294; GO:0004386; GO:0046872; GO:0045448; GO:0007279; GO:0070883; GO:0031054; GO:0030422; GO:0007367; GO:0035087; GO:0003727,"ATP binding; RISC complex; bidentate ribonuclease III activity; cytoplasm; dendrite morphogenesis; double-stranded RNA binding; dsRNA transport; germ-line stem cell division; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; helicase activity; metal ion binding; mitotic cell cycle, embryonic; pole cell formation; pre-miRNA binding; pre-miRNA processing; production of siRNA involved in RNA interference; segment polarity determination; siRNA loading onto RISC involved in RNA interference; single-stranded RNA binding",PF03368;PF00271;PF02170;PF00636;,5.00E-38,CHOYP_DICER.1.3,,,,,,,DCR1_DROME,Drosophila melanogaster (Fruit fly),"apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line stem cell division [GO:0042078]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; response to starvation [GO:0042594]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]" comp149892_c0_seq1,270,44.0741,0.07814409,14,0,,7.00E-31,Q8NB59,Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV),Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV),GO:0008219; GO:0016021; GO:0005543,cell death; integral to membrane; phospholipid binding,PF00168;,5.00E-45,CHOYP_LOC100369472.2.2,,,,,,,SYT14_HUMAN,Homo sapiens (Human),vesicle fusion [GO:0006906] comp149895_c0_seq1,225,41.7778,0.40942838,9,4,,6.00E-08,A0JPH4,Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),GO:0012507; GO:0000139; GO:0008203; GO:0005789; GO:0016021,ER to Golgi transport vesicle membrane; Golgi membrane; cholesterol metabolic process; endoplasmic reticulum membrane; integral to membrane,PF12349;PF00400;,,,,,,,,,SCAP_XENLA,Xenopus laevis (African clawed frog),cholesterol metabolic process [GO:0008203]; SREBP signaling pathway [GO:0032933] comp149907_c0_seq1,212,42.9245,0.63019154,1,12,,8.00E-06,Q9GK38,"Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)","Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)",GO:0031032,actomyosin structure organization,PF00402;PF00307;,,,,,,,,,CNN1_MUSPF,Mustela putorius furo (European domestic ferret) (Mustela furo),actomyosin structure organization [GO:0031032] comp149927_c0_seq1,554,43.8628,0.41729459,15,11,,3.00E-36,Q99KW9,T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1),T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin),GO:0005576; GO:0016021,extracellular region; integral to membrane,,,,,,,,,,TIP_MOUSE,Mus musculus (Mouse), comp149937_c0_seq1,285,46.3158,0.52719543,13,0,,2.00E-10,Q8GYF5,Wall-associated receptor kinase-like 21 (EC 2.7.11.-),Wall-associated receptor kinase-like 21 (EC 2.7.11.-),GO:0005524; GO:0016021; GO:0004674,ATP binding; integral to membrane; protein serine/threonine kinase activity,PF07714;,,,,,,,,,WAKLR_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell surface receptor signaling pathway [GO:0007166] comp149954_c0_seq1,284,43.662,0.23265595,15,0,,8.00E-34,P23098,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-51,CHOYP_DYHC.1.3,,,,,,,DYHC_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp149956_c0_seq1,283,60.0707,0.98489231,0,17,,1.00E-09,P42063,Oligopeptide transport system permease protein AppC,Oligopeptide transport system permease protein AppC,GO:0030420; GO:0016021; GO:0015833; GO:0005886; GO:0015031; GO:0030435; GO:0005215,establishment of competence for transformation; integral to membrane; peptide transport; plasma membrane; protein transport; sporulation resulting in formation of a cellular spore; transporter activity,PF00528;PF12911;,,,,,,,,,APPC_BACSU,Bacillus subtilis (strain 168),establishment of competence for transformation [GO:0030420]; nickel cation transmembrane transport [GO:0035444]; peptide transport [GO:0015833]; protein transport [GO:0015031]; sporulation resulting in formation of a cellular spore [GO:0030435] comp149960_c0_seq1,336,39.2857,0.58003956,8,9,,,,,,,,,,,4.00E-32,ruditapes_c14987,,,,,,, comp149964_c0_seq1,320,46.25,0.35197712,6,7,,3.00E-08,Q8MVR1,Cyclic GMP-binding protein C (EC 2.7.11.1) (Ras guanine nucleotide exchange factor T) (RasGEF domain-containing protein T),Cyclic GMP-binding protein C (EC 2.7.11.1) (Ras guanine nucleotide exchange factor T) (RasGEF domain-containing protein T),GO:0005524; GO:0005525; GO:0005088; GO:0030553; GO:0019934; GO:0031589; GO:0005737; GO:0007163; GO:0005543; GO:0046579; GO:0051272; GO:0045860; GO:0004674; GO:0050920; GO:0007264,ATP binding; GTP binding; Ras guanyl-nucleotide exchange factor activity; cGMP binding; cGMP-mediated signaling; cell-substrate adhesion; cytoplasm; establishment or maintenance of cell polarity; phospholipid binding; positive regulation of Ras protein signal transduction; positive regulation of cellular component movement; positive regulation of protein kinase activity; protein serine/threonine kinase activity; regulation of chemotaxis; small GTPase mediated signal transduction,PF00027;PF16095;PF00610;PF02893;PF07714;PF00617;PF00618;PF08477;,,,,,,,,,GBPC_DICDI,Dictyostelium discoideum (Slime mold),cell-substrate adhesion [GO:0031589]; cGMP-mediated signaling [GO:0019934]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of cellular component movement [GO:0051272]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of chemotaxis [GO:0050920]; small GTPase mediated signal transduction [GO:0007264] comp149966_c0_seq1,203,48.7685,0.99920792,6,5,,3.00E-38,P62282,40S ribosomal protein S11,40S ribosomal protein S11,GO:0022627; GO:0019843; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; rRNA binding; structural constituent of ribosome; translation,PF00366;PF16205;,5.00E-50,CHOYP_RPS11.5.5,2.00E-45,ruditapes_lrc33424,,,,,RS11_RAT,Rattus norvegicus (Rat),osteoblast differentiation [GO:0001649]; translation [GO:0006412] comp149973_c0_seq1,518,38.61,0.83449211,7,26,,2.00E-74,Q5U395,CTD nuclear envelope phosphatase 1A (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard-A),CTD nuclear envelope phosphatase 1A (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard-A),GO:0071595; GO:0005789; GO:0016021; GO:0006998; GO:0031965; GO:0010867; GO:0006470; GO:0004722,Nem1-Spo7 phosphatase complex; endoplasmic reticulum membrane; integral to membrane; nuclear envelope organization; nuclear membrane; positive regulation of triglyceride biosynthetic process; protein dephosphorylation; protein serine/threonine phosphatase activity,PF03031;,3.00E-82,CHOYP_ISCW_ISCW008600.1.1,,,,,,,CNEPA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nuclear envelope organization [GO:0006998]; positive regulation of triglyceride biosynthetic process [GO:0010867]; protein dephosphorylation [GO:0006470] comp149977_c0_seq1,581,38.3821,0.19144794,20,9,,,,,,,,,4.00E-19,CHOYP_BRAFLDRAFT_119590.3.3,,,,,,,,, comp149982_c0_seq1,301,41.8605,0.99142508,2,10,,6.00E-10,Q96MB7,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_HUMAN,Homo sapiens (Human), comp149984_c0_seq1,210,44.7619,0.8596845,0,12,,2.00E-07,Q19673,Putative tyrosinase-like protein tyr-3,Putative tyrosinase-like protein tyr-3,GO:0046872; GO:0004497,metal ion binding; monooxygenase activity,PF01549;PF00264;,,,,,,,,,TYR3_CAEEL,Caenorhabditis elegans, comp150000_c0_seq1,484,47.1074,0.44907599,15,7,,2.00E-41,Q924N4,Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),GO:0016323; GO:0071477; GO:0016021; GO:0006813; GO:0015379,basolateral plasma membrane; cellular hypotonic salinity response; integral to membrane; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,2.00E-33,CHOYP_DPER_GL11178.1.1,,,,,,,S12A6_MOUSE,Mus musculus (Mouse),cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826] comp150004_c0_seq1,319,39.8119,0.55721941,3,9,,6.00E-23,P18713,Gastrula zinc finger protein XlCGF17.1 (Fragment),Gastrula zinc finger protein XlCGF17.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG17_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp150009_c0_seq1,230,57.3913,1.22676066,0,15,,2.00E-10,P50442,"Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase)","Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase)",GO:0015067; GO:0006601; GO:0009790; GO:0015068; GO:0016813; GO:0005743; GO:0005758; GO:0046689; GO:0007584; GO:0006979; GO:0043434; GO:0042246,"amidinotransferase activity; creatine biosynthetic process; embryo development; glycine amidinotransferase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; mitochondrial inner membrane; mitochondrial intermembrane space; response to mercury ion; response to nutrient; response to oxidative stress; response to peptide hormone stimulus; tissue regeneration",,,,,,,,,,GATM_RAT,Rattus norvegicus (Rat),creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; response to mercury ion [GO:0046689]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; tissue regeneration [GO:0042246] comp150017_c0_seq1,273,38.8278,0.98811279,3,15,,5.00E-07,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp150018_c0_seq1,243,43.2099,0.62245952,5,6,,1.00E-08,Q0VCJ6,Zinc finger and BTB domain-containing protein 8A,Zinc finger and BTB domain-containing protein 8A,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT8A_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp150025_c0_seq1,389,41.1311,1.03740319,14,0,,5.00E-08,Q496A3,Spermatogenesis-associated serine-rich protein 1,Spermatogenesis-associated serine-rich protein 1,,,PF15160;,,,,,,,,,SPAS1_HUMAN,Homo sapiens (Human), comp150029_c0_seq1,337,46.2908,0.27782589,9,7,,8.00E-32,A0JM23,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0060271; GO:0090090; GO:0072372; GO:2000095,"Wnt receptor signaling pathway; cilium morphogenesis; negative regulation of canonical Wnt receptor signaling pathway; primary cilium; regulation of Wnt receptor signaling pathway, planar cell polarity pathway",PF13176;,,,,,,,,,NPHP3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cilium morphogenesis [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]" comp150043_c0_seq1,254,43.7008,0.16591018,5,6,,1.00E-08,A4IFI1,Coiled-coil domain-containing protein 157,Coiled-coil domain-containing protein 157,,,,3.00E-15,CHOYP_LOC100367713.1.1,,,,,,,CC157_BOVIN,Bos taurus (Bovine), comp150064_c0_seq1,242,50.8264,0.57827534,0,12,,2.00E-11,P34299,Glutamate receptor 1,Glutamate receptor 1,GO:0004971; GO:0030054; GO:0030425; GO:0005234; GO:0007631; GO:0006972; GO:0008328; GO:0032589; GO:0043025; GO:0014069; GO:0045211; GO:0009612; GO:0050913; GO:0007614; GO:0035249; GO:0001966,"alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; cell junction; dendrite; extracellular-glutamate-gated ion channel activity; feeding behavior; hyperosmotic response; ionotropic glutamate receptor complex; neuron projection membrane; neuronal cell body; postsynaptic density; postsynaptic membrane; response to mechanical stimulus; sensory perception of bitter taste; short-term memory; synaptic transmission, glutamatergic; thigmotaxis",PF01094;PF00060;PF10613;,,,,,,,,,GLR1_CAEEL,Caenorhabditis elegans,"adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; feeding behavior [GO:0007631]; forward locomotion [GO:0043056]; habituation [GO:0046959]; hyperosmotic response [GO:0006972]; ionotropic glutamate receptor signaling pathway [GO:0035235]; regulation of backward locomotion [GO:0043058]; response to mechanical stimulus [GO:0009612]; sensory perception of bitter taste [GO:0050913]; short-term memory [GO:0007614]; synaptic transmission, glutamatergic [GO:0035249]; thigmotaxis [GO:0001966]" comp150068_c0_seq1,333,61.5616,1.17491777,1,9,,1.00E-34,Q73WH4,Exodeoxyribonuclease 7 large subunit (EC 3.1.11.6) (Exodeoxyribonuclease VII large subunit) (Exonuclease VII large subunit),Exodeoxyribonuclease 7 large subunit (EC 3.1.11.6) (Exodeoxyribonuclease VII large subunit) (Exonuclease VII large subunit),GO:0006308; GO:0005737; GO:0008855; GO:0009318; GO:0003676; GO:0090305,DNA catabolic process; cytoplasm; exodeoxyribonuclease VII activity; exodeoxyribonuclease VII complex; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF02601;PF13742;,,,,,,,,,EX7L_MYCPA,Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10),DNA catabolic process [GO:0006308] comp150070_c0_seq1,208,69.7115,0.99792223,0,12,,2.00E-16,O07549,Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (EC 3.6.3.-),Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (EC 3.6.3.-),GO:0005524; GO:0042626; GO:0016021; GO:0005886; GO:0046677,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; response to antibiotic",PF00664;PF00005;,,,,,,,,,YHEH_BACSU,Bacillus subtilis (strain 168),response to antibiotic [GO:0046677] comp150076_c0_seq1,279,44.086,0.30189067,10,4,,5.00E-11,Q5ZKD7,Putative helicase MOV-10 (EC 3.6.4.13),Putative helicase MOV-10 (EC 3.6.4.13),GO:0005524; GO:0003723; GO:0000932; GO:0004386; GO:0035279,ATP binding; RNA binding; cytoplasmic mRNA processing body; helicase activity; mRNA cleavage involved in gene silencing by miRNA,,,,,,,,,,MOV10_CHICK,Gallus gallus (Chicken),gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279] comp150082_c0_seq1,277,46.5704,0.66827794,6,7,,1.00E-18,Q5XF89,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,1.00E-15,CHOYP_PHUM_PHUM193930.1.1,,,,,,,AT133_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp150087_c0_seq1,280,43.9286,0.89634317,3,13,,8.00E-24,O42457,Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1),Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP1A1_SPAAU,Sparus aurata (Gilthead sea bream), comp150090_c0_seq1,294,49.6599,0.56644281,5,11,,4.00E-13,Q5FW46,Protein FAM214A,Protein FAM214A,,,PF13889;PF13915;,,,,,,,,,F214A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp150108_c0_seq1,227,42.2907,0.90041238,4,7,,5.00E-07,Q494W8,CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10),CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10),GO:0005230; GO:0016021,extracellular ligand-gated ion channel activity; integral to membrane,PF02931;PF02932;,,,,,,,,,CRFM7_HUMAN,Homo sapiens (Human), comp150125_c0_seq1,241,43.5685,0.35510516,5,7,,2.00E-11,P18956,Gamma-glutamyltranspeptidase (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain],Gamma-glutamyltranspeptidase (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain],GO:0003840; GO:0006750; GO:0036374; GO:0042597,gamma-glutamyltransferase activity; glutathione biosynthetic process; glutathione hydrolase activity; periplasmic space,PF01019;,,,,,,,,,GGT_ECOLI,Escherichia coli (strain K12),glutathione biosynthetic process [GO:0006750] comp150141_c0_seq1,241,54.7718,1.22252392,0,16,,1.00E-12,A0QX20,Aconitate hydratase (EC 4.2.1.3),"Aconitate hydratase A (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (Iron-responsive protein-like) (IRP-like) (Probable 2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (RNA-binding protein)",GO:0003994; GO:0051536; GO:0046872; GO:0006099,aconitate hydratase activity; iron-sulfur cluster binding; metal ion binding; tricarboxylic acid cycle,PF00330;PF00694;,,,,,,,,,ACON_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),tricarboxylic acid cycle [GO:0006099] comp150143_c0_seq1,576,43.0556,0.6386087,24,0,,9.00E-18,Q8NA19,Lethal(3)malignant brain tumor-like protein 4 (H-l(3)mbt-like protein 4) (L(3)mbt-like protein 4),Lethal(3)malignant brain tumor-like protein 4 (H-l(3)mbt-like protein 4) (L(3)mbt-like protein 4),GO:0016568; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"chromatin modification; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF02820;PF00536;PF01530;,,,,,,,,,LMBL4_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]" comp150146_c0_seq1,210,54.2857,0.78806642,0,11,,2.00E-26,P42656,DNA damage checkpoint protein rad24,DNA damage checkpoint protein rad24,GO:0000077; GO:0006281; GO:0032153; GO:0034613; GO:0034644; GO:0071277; GO:0071472; GO:0009267; GO:0031565; GO:0005829; GO:0007126; GO:0044732; GO:0010515; GO:0043433; GO:0000122; GO:0031031; GO:0004864; GO:0051233,DNA damage checkpoint; DNA repair; cell division site; cellular protein localization; cellular response to UV; cellular response to calcium ion; cellular response to salt stress; cellular response to starvation; cytokinesis checkpoint; cytosol; meiosis; mitotic spindle pole body; negative regulation of induction of conjugation with cellular fusion; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of septation initiation signaling cascade; protein phosphatase inhibitor activity; spindle midzone,PF00244;,,,,,,,,,RAD24_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cellular protein localization [GO:0034613]; cytoplasmic sequestering of protein [GO:0051220]; meiotic cell cycle [GO:0051321]; mitotic cytokinesis checkpoint [GO:0044878]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of induction of conjugation with cellular fusion [GO:0010515]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of septation initiation signaling [GO:0031031] comp150147_c0_seq1,313,33.8658,0.33727519,0,14,,2.00E-12,Q9UDV7,Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1),Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1),GO:0003677; GO:0045892; GO:0005634; GO:0006351; GO:0008270,"DNA binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent; zinc ion binding",PF12417;PF01352;PF00096;PF13912;,,,,,,,,,ZN282_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp150154_c0_seq1,232,46.9828,0.79253173,5,10,,4.00E-34,P32870,Ca(2+)/calmodulin-responsive adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Protein rutabaga),Ca(2+)/calmodulin-responsive adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Protein rutabaga),GO:0005524; GO:0007186; GO:0048675; GO:0048149; GO:0019933; GO:0008294; GO:0001661; GO:0007619; GO:0008340; GO:0007625; GO:0016021; GO:0016020; GO:0046872; GO:0007591; GO:0007528; GO:0007274; GO:0008355; GO:0090328; GO:0009408; GO:0006979; GO:0007614; GO:0030431,"ATP binding; G-protein coupled receptor signaling pathway; axon extension; behavioral response to ethanol; cAMP-mediated signaling; calcium- and calmodulin-responsive adenylate cyclase activity; conditioned taste aversion; courtship behavior; determination of adult lifespan; grooming behavior; integral to membrane; membrane; metal ion binding; molting cycle, chitin-based cuticle; neuromuscular junction development; neuromuscular synaptic transmission; olfactory learning; regulation of olfactory learning; response to heat; response to oxidative stress; short-term memory; sleep",PF16214;PF06327;PF00211;,2.00E-24,CHOYP_APLA.2.2,,,,,,,CYA1_DROME,Drosophila melanogaster (Fruit fly),"adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; associative learning [GO:0008306]; axon extension [GO:0048675]; behavioral response to ethanol [GO:0048149]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; courtship behavior [GO:0007619]; cyclic nucleotide biosynthetic process [GO:0009190]; determination of adult lifespan [GO:0008340]; G-protein coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; learning [GO:0007612]; learning or memory [GO:0007611]; mating behavior [GO:0007617]; memory [GO:0007613]; molting cycle, chitin-based cuticle [GO:0007591]; neuromuscular junction development [GO:0007528]; neuromuscular synaptic transmission [GO:0007274]; olfactory learning [GO:0008355]; regulation of olfactory learning [GO:0090328]; regulation of protein kinase A signaling [GO:0010738]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; short-term memory [GO:0007614]; sleep [GO:0030431]" comp150156_c0_seq1,246,46.3415,0.71068949,4,6,,5.00E-12,Q96AP4,Zinc finger with UFM1-specific peptidase domain protein,Zinc finger with UFM1-specific peptidase domain protein,GO:0046872,metal ion binding,PF07910;,,,,,,,,,ZUFSP_HUMAN,Homo sapiens (Human), comp150159_c0_seq1,216,46.7593,0.35574533,2,9,,3.00E-15,Q7TQF2,F-box only protein 10,F-box only protein 10,,,PF12937;PF05048;,5.00E-44,CHOYP_FBX10.1.1,,,,,,,FBX10_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of apoptotic process [GO:0042981] comp150177_c0_seq1,375,45.0667,0.89524446,9,8,,2.00E-07,O60494,Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0009235; GO:0015889; GO:0005829; GO:0030139; GO:0005783; GO:0010008; GO:0031232; GO:0042157; GO:0042953; GO:0043202; GO:0005765; GO:0042803; GO:0004872; GO:0006898; GO:0001894; GO:0005215; GO:0042359,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; cobalamin metabolic process; cobalamin transport; cytosol; endocytic vesicle; endoplasmic reticulum; endosome membrane; extrinsic to external side of plasma membrane; lipoprotein metabolic process; lipoprotein transport; lysosomal lumen; lysosomal membrane; protein homodimerization activity; receptor activity; receptor-mediated endocytosis; tissue homeostasis; transporter activity; vitamin D metabolic process,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_HUMAN,Homo sapiens (Human),cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359] comp150180_c0_seq1,457,43.7637,0.52479418,20,5,,1.00E-12,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp150189_c0_seq1,304,65.4605,1.00723484,0,23,,2.00E-31,A1WB52,30S ribosomal protein S16,30S ribosomal protein S16,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00886;,,,,,,,,,RS16_ACISJ,Acidovorax sp. (strain JS42),translation [GO:0006412] comp150195_c0_seq1,242,48.7603,0.76811656,0,13,,5.00E-09,H2A0M3,Putative amine oxidase [copper-containing] (EC 1.4.3.-),Putative amine oxidase [copper-containing] (EC 1.4.3.-),GO:0009308; GO:0005507; GO:0005576; GO:0008131; GO:0048038,amine metabolic process; copper ion binding; extracellular region; primary amine oxidase activity; quinone binding,PF01179;,,,,,,,,,AMO_PINMG,Pinctada margaritifera (Black-lipped pearl oyster),amine metabolic process [GO:0009308] comp150202_c0_seq1,333,41.7417,0.43377015,4,11,,5.00E-15,Q6ZSB9,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp150210_c0_seq1,265,40,0.19000271,4,9,,2.00E-32,Q9Y256,CAAX prenyl protease 2 (EC 3.4.22.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1),CAAX prenyl protease 2 (EC 3.4.22.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1),GO:0071586; GO:0004197; GO:0005789; GO:0005887; GO:0004222; GO:0006508,CAAX-box protein processing; cysteine-type endopeptidase activity; endoplasmic reticulum membrane; integral to plasma membrane; metalloendopeptidase activity; proteolysis,PF02517;,4.00E-20,CHOYP_LOC100115515.1.1,,,,,,,FACE2_HUMAN,Homo sapiens (Human),CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508] comp150219_c0_seq1,288,47.5694,0.96120893,5,12,,1.00E-12,P21789,Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase),Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase),GO:0005509; GO:0005576; GO:0016042; GO:0004623; GO:0006644,calcium ion binding; extracellular region; lipid catabolic process; phospholipase A2 activity; phospholipid metabolic process,PF00068;,,,,,,,,,PA2A_CERCE,Cerastes cerastes (Horned desert viper),lipid catabolic process [GO:0016042] comp150263_c0_seq1,202,40.5941,1.10328791,1,15,,7.00E-08,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp150265_c0_seq1,247,38.0567,0.73920735,3,8,,8.00E-15,Q9D818,Suppressor APC domain-containing protein 2 (Protein Ang),Suppressor APC domain-containing protein 2 (Protein Ang),GO:0005737; GO:0005730,cytoplasm; nucleolus,,,,,,,,,,SAPC2_MOUSE,Mus musculus (Mouse), comp150281_c0_seq1,305,44.5902,1.19118928,6,8,,2.00E-23,Q9UL62,Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5),Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5),GO:0007411; GO:0034704; GO:0070679; GO:0005887; GO:0015279,"axon guidance; calcium channel complex; inositol 1,4,5 trisphosphate binding; integral to plasma membrane; store-operated calcium channel activity",PF12796;PF00520;PF08344;,2.00E-32,CHOYP_TRPC6.1.2,,,,,,,TRPC5_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; manganese ion transport [GO:0006828]; nervous system development [GO:0007399]; regulation of cytosolic calcium ion concentration [GO:0051480] comp150285_c0_seq1,262,48.855,0.79397383,18,0,,2.00E-09,Q9ULY5,C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin),C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin),GO:0030246; GO:0006955; GO:0016021; GO:0050715; GO:0004872,carbohydrate binding; immune response; integral to membrane; positive regulation of cytokine secretion; receptor activity,PF00059;,,,,,,,,,CLC4E_HUMAN,Homo sapiens (Human),defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; positive regulation of cytokine secretion [GO:0050715]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell differentiation involved in immune response [GO:0002292] comp150291_c0_seq1,225,38.6667,0.47933078,13,0,,3.00E-08,Q9NZU1,Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1),Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1),GO:0007155; GO:0005887; GO:0030674; GO:0005578; GO:0005057,"cell adhesion; integral to plasma membrane; protein binding, bridging; proteinaceous extracellular matrix; receptor signaling protein activity",PF13855;PF01462;,,,,,,,,,FLRT1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; dendrite development [GO:0016358]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; neuron projection extension [GO:1990138]; positive regulation of synapse assembly [GO:0051965] comp150298_c0_seq1,669,43.0493,0.42022577,24,9,,3.00E-63,Q6VAB6,Kinase suppressor of Ras 2 (hKSR2),Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0035556; GO:0016020; GO:0046872; GO:0004674,ATP binding; cytoplasm; intracellular signal transduction; membrane; metal ion binding; protein serine/threonine kinase activity,PF13543;PF07714;,1.00E-44,CHOYP_KSR2.1.1,,,,,,,KSR2_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp150317_c0_seq1,238,45.7983,0.32407352,1,12,,9.00E-07,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp150352_c0_seq1,201,40.2985,0,3,7,,1.00E-07,Q2QI47,Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog),Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog),GO:0016324; GO:0005604; GO:0005518; GO:0005737; GO:0035315; GO:0060113; GO:0016021; GO:0048496; GO:0045494; GO:0050896; GO:0007605; GO:0002142; GO:0060171; GO:0007601,apical plasma membrane; basement membrane; collagen binding; cytoplasm; hair cell differentiation; inner ear receptor cell differentiation; integral to membrane; maintenance of organ identity; photoreceptor cell maintenance; response to stimulus; sensory perception of sound; stereocilia ankle link complex; stereocilium membrane; visual perception,PF00041;PF00053;PF00054;PF02210;PF00055;,,,,,,,,,USH2A_MOUSE,Mus musculus (Mouse),establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear receptor cell differentiation [GO:0060113]; maintenance of organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp150354_c0_seq1,289,38.0623,0.31798626,3,4,,,,,,,,,3.00E-16,CHOYP_BRAFLDRAFT_63247.1.1,,,,,,,,, comp150362_c0_seq1,292,57.5342,0.99887535,0,15,,9.00E-37,Q9CD72,ATP-dependent DNA helicase UvrD1 (EC 3.6.4.12),ATP-dependent DNA helicase UvrD1 (EC 3.6.4.12),GO:0005524; GO:0004003; GO:0003677; GO:0006281,ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair,PF00580;PF13361;,,,,,,,,,UVRD1_MYCLE,Mycobacterium leprae (strain TN),DNA repair [GO:0006281] comp150363_c0_seq1,265,46.0377,1.00759011,12,0,,7.00E-39,Q9QXN5,Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase),Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase),GO:0050661; GO:0004033; GO:0005737; GO:0008199; GO:0016234; GO:0019310; GO:0050113; GO:0016651,"NADP binding; aldo-keto reductase (NADP) activity; cytoplasm; ferric iron binding; inclusion body; inositol catabolic process; inositol oxygenase activity; oxidoreductase activity, acting on NAD(P)H",PF05153;,,,3.00E-45,ruditapes2_c2191,,,,,MIOX_MOUSE,Mus musculus (Mouse),inositol catabolic process [GO:0019310] comp150391_c0_seq1,243,38.2716,0.56430188,0,15,,,,,,,,,,,1.00E-12,ruditapes_c7836,,,,,,, comp150398_c0_seq1,372,36.828,0.64589211,3,14,,4.00E-13,P13360,Protein glass,Protein glass,GO:0003677; GO:0003705; GO:0001752; GO:0043153; GO:0046872; GO:0005634; GO:0045944; GO:0010114; GO:0035271; GO:0007605; GO:0007601,DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; compound eye photoreceptor fate commitment; entrainment of circadian clock by photoperiod; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to red light; ring gland development; sensory perception of sound; visual perception,PF00096;,,,,,,,,,GLAS_DROME,Drosophila melanogaster (Fruit fly),"circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp150400_c0_seq1,280,49.2857,0.44332321,2,13,,1.00E-12,Q8VHK8,Transmembrane protease serine 11D (EC 3.4.21.-) (Adrenal secretory serine protease) (AsP) (Airway trypsin-like protease) (AT) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain],Transmembrane protease serine 11D (EC 3.4.21.-) (Adrenal secretory serine protease) (AsP) (Airway trypsin-like protease) (AT) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain],GO:0005576; GO:0005887; GO:0006508; GO:0004252,extracellular region; integral to plasma membrane; proteolysis; serine-type endopeptidase activity,PF01390;PF00089;,,,,,,,,,TM11D_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp150411_c0_seq1,221,39.819,0.11473103,1,6,,4.00E-17,Q5ZI67,NHL repeat-containing protein 2,NHL repeat-containing protein 2,,,PF01436;PF13905;,,,,,,,,,NHLC2_CHICK,Gallus gallus (Chicken), comp150418_c0_seq1,237,41.3502,0.39717019,3,10,,2.00E-13,O95263,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)","High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)",GO:0004114; GO:0006198; GO:0009187; GO:0005829; GO:0035556; GO:0046872; GO:0046676; GO:0000156; GO:0006355,"3',5'-cyclic-nucleotide phosphodiesterase activity; cAMP catabolic process; cyclic nucleotide metabolic process; cytosol; intracellular signal transduction; metal ion binding; negative regulation of insulin secretion; phosphorelay response regulator activity; regulation of transcription, DNA-dependent",PF13426;PF08629;PF00233;,,,,,,,,,PDE8B_HUMAN,Homo sapiens (Human),cAMP catabolic process [GO:0006198]; cyclic nucleotide metabolic process [GO:0009187]; negative regulation of insulin secretion [GO:0046676]; signal transduction [GO:0007165] comp150428_c0_seq1,264,42.4242,0.55209125,6,6,,2.00E-18,P07207,Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],GO:0005796; GO:0061382; GO:0007219; GO:0048052; GO:0007464; GO:0045466; GO:0045463; GO:0007460; GO:0007015; GO:0005912; GO:0008356; GO:0007298; GO:0005509; GO:0009986; GO:0008407; GO:0003682; GO:0042676; GO:0046667; GO:0005829; GO:0008340; GO:0046843; GO:0007391; GO:0007451; GO:0007398; GO:0035165; GO:0005788; GO:0005768; GO:0061331; GO:0035153; GO:0035214; GO:0007440; GO:0060288; GO:0030718; GO:0030708; GO:0007403; GO:0008347; GO:0035172; GO:0007157; GO:0007446; GO:0016348; GO:0048803; GO:0008587; GO:0007474; GO:0016021; GO:0035171; GO:0046331; GO:0007616; GO:0035170; GO:0007498; GO:0008045; GO:0007521; GO:0046329; GO:0045316; GO:0035157; GO:0050768; GO:0035155; GO:0000122; GO:0007400; GO:0005654; GO:0007314; GO:0030720; GO:0030713; GO:0007422; GO:1900087; GO:0045747; GO:0008284; GO:0045944; GO:0043234; GO:0045468; GO:0042686; GO:0042689; GO:0051489; GO:0040008; GO:0009608; GO:0016330; GO:0007519; GO:0035003; GO:0006351; GO:0004888; GO:0007419; GO:0048190; GO:0007473,"Golgi lumen; Malpighian tubule tip cell differentiation; Notch signaling pathway; R1/R6 cell differentiation; R3/R4 cell fate commitment; R7 cell differentiation; R8 cell development; R8 cell fate commitment; actin filament organization; adherens junction; asymmetric cell division; border follicle cell migration; calcium ion binding; cell surface; chaeta morphogenesis; chromatin binding; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; cytosol; determination of adult lifespan; dorsal appendage formation; dorsal closure; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; embryonic crystal cell differentiation; endoplasmic reticulum lumen; endosome; epithelial cell proliferation involved in Malpighian tubule morphogenesis; epithelial cell type specification, open tracheal system; eye-antennal disc development; foregut morphogenesis; formation of a compartment boundary; germ-line stem cell maintenance; germarium-derived female germ-line cyst encapsulation; glial cell fate determination; glial cell migration; hemocyte proliferation; heterophilic cell-cell adhesion; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived male genitalia morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; lamellocyte differentiation; lateral inhibition; long-term memory; lymph gland crystal cell differentiation; mesoderm development; motor neuron axon guidance; muscle cell fate determination; negative regulation of JNK cascade; negative regulation of compound eye photoreceptor development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleoplasm; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of Notch signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of R8 cell spacing in compound eye; regulation of cardioblast cell fate specification; regulation of crystal cell differentiation; regulation of filopodium assembly; regulation of growth; response to symbiont; second mitotic wave involved in compound eye morphogenesis; skeletal muscle tissue development; subapical complex; transcription, DNA-dependent; transmembrane signaling receptor activity; ventral cord development; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTCH_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]" comp150432_c0_seq1,217,46.5438,0.51700703,2,9,,4.00E-18,Q1ZXJ0,Chloride channel protein D,Chloride channel protein D,GO:0030554; GO:0034707; GO:0030587; GO:0005247,adenyl nucleotide binding; chloride channel complex; sorocarp development; voltage-gated chloride channel activity,PF00571;PF00654;,,,,,,,,,CLCD_DICDI,Dictyostelium discoideum (Slime mold),sorocarp development [GO:0030587] comp150438_c0_seq1,215,45.1163,0.64838452,5,8,,5.00E-12,Q8C033,Rho guanine nucleotide exchange factor 10,Rho guanine nucleotide exchange factor 10,GO:0005089; GO:0035023,Rho guanyl-nucleotide exchange factor activity; regulation of Rho protein signal transduction,PF00621;,5.00E-12,CHOYP_PHUM_PHUM169900.1.2,,,,,,,ARHGA_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496]; regulation of Rho protein signal transduction [GO:0035023] comp150444_c0_seq1,246,47.9675,0.3632413,1,15,,2.00E-19,Q9Y573,Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27),Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27),GO:0003779; GO:0015629; GO:0005737,actin binding; actin cytoskeleton; cytoplasm,PF07707;PF00651;PF01344;,,,,,,,,,IPP_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp150452_c0_seq1,331,36.858,0.45844108,8,4,,,,,,,,,,,7.00E-29,ruditapes_c21717,,,,,,, comp150457_c0_seq1,404,42.3267,0.8393254,6,19,,6.00E-11,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp150482_c0_seq1,222,58.5586,1.11079104,0,11,,3.00E-07,Q9CIV7,"PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL (EC 2.7.-.-)","PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL (EC 2.7.-.-)",GO:0005524; GO:0019563; GO:0004371,ATP binding; glycerol catabolic process; glycerone kinase activity,PF02734;,,,,,,,,,DHAL_LACLA,Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis),glycerol catabolic process [GO:0019563] comp150488_c0_seq1,471,40.9766,0.42666859,3,18,,6.00E-17,Q99MH6,Protein naked cuticle homolog 1 (Naked-1) (mNkd) (mNkd1),Protein naked cuticle homolog 1 (Naked-1) (mNkd) (mNkd1),GO:0016055; GO:0005509; GO:0030154; GO:0005737; GO:0007275; GO:0090090; GO:1901233; GO:0005886; GO:2000096; GO:1901231; GO:0045732; GO:0000159; GO:0007283,"Wnt receptor signaling pathway; calcium ion binding; cell differentiation; cytoplasm; multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of convergent extension involved in axis elongation; plasma membrane; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade; positive regulation of protein catabolic process; protein phosphatase type 2A complex; spermatogenesis",,4.00E-30,CHOYP_NKD1.1.1,,,,,,,NKD1_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of convergent extension involved in axis elongation [GO:1901233]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of non-canonical Wnt signaling pathway via JNK cascade [GO:1901231]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]" comp150493_c0_seq1,264,40.1515,1.13249488,1,12,,3.00E-31,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp150495_c0_seq1,218,40.8257,0.23422953,3,10,,9.00E-15,Q5SNX7,Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),GO:0005975; GO:0004336; GO:0006683; GO:0005764,carbohydrate metabolic process; galactosylceramidase activity; galactosylceramide catabolic process; lysosome,PF02057;,,,,,,,,,GALC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683] comp150502_c0_seq1,209,38.2775,0.6836094,0,12,,2.00E-07,Q47944,L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32),L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32),GO:0006066; GO:0008812; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding,PF05199;PF00732;,,,,,,,,,SDH_GLUOY,Gluconobacter oxydans (Gluconobacter suboxydans), comp150503_c0_seq1,247,41.2955,0.19136116,0,13,,2.00E-08,Q3UTZ3,Uncharacterized protein C7orf43 homolog,Uncharacterized protein C7orf43 homolog,,,PF15806;,,,,,,,,,CG043_MOUSE,Mus musculus (Mouse), comp150513_c0_seq1,224,44.1964,0.7475232,2,9,,,,,,,,,2.00E-16,CHOYP_LOC100180193.2.2,3.00E-56,ruditapes_c17993,,,,,,, comp150518_c0_seq1,259,42.8571,0.93465446,5,6,,3.00E-30,Q8R3I2,Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (mLPCAT4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2),Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (mLPCAT4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2),GO:0047184; GO:0005783; GO:0016021; GO:0008654,1-acylglycerophosphocholine O-acyltransferase activity; endoplasmic reticulum; integral to membrane; phospholipid biosynthetic process,PF03062;,,,,,,,,,MBOA2_MOUSE,Mus musculus (Mouse),phospholipid biosynthetic process [GO:0008654] comp150531_c0_seq1,251,49.4024,0.26332706,10,4,,1.00E-31,Q96JB1,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-66,CHOYP_DNAH5.2.2,,,,,,,DYH8_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp150541_c0_seq1,318,42.1384,0.35923779,7,14,,5.00E-28,Q9D1E8,1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon),1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon),GO:0003841; GO:0016024; GO:0006639; GO:0005789; GO:0016021; GO:0005739; GO:0005635,1-acylglycerol-3-phosphate O-acyltransferase activity; CDP-diacylglycerol biosynthetic process; acylglycerol metabolic process; endoplasmic reticulum membrane; integral to membrane; mitochondrion; nuclear envelope,PF16076;PF01553;,,,,,,,,,PLCE_MOUSE,Mus musculus (Mouse),acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244] comp150556_c0_seq1,210,48.5714,1.11642743,0,13,,2.00E-09,P80147,"4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)","4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)",GO:0047298; GO:0003867; GO:0032144; GO:0048148; GO:0005829; GO:0009450; GO:0005759; GO:0042135; GO:0042803; GO:0030170; GO:0032145,(S)-3-amino-2-methylpropionate transaminase activity; 4-aminobutyrate transaminase activity; 4-aminobutyrate transaminase complex; behavioral response to cocaine; cytosol; gamma-aminobutyric acid catabolic process; mitochondrial matrix; neurotransmitter catabolic process; protein homodimerization activity; pyridoxal phosphate binding; succinate-semialdehyde dehydrogenase binding,PF00202;,,,,,,,,,GABT_PIG,Sus scrofa (Pig),behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135] comp150590_c0_seq1,231,48.9177,0.4360984,6,4,,3.00E-06,B1AUH1,Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Ftp-1) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase-lamda) (PTP-lambda) (PTPlambda) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi),Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Ftp-1) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase-lamda) (PTP-lambda) (PTPlambda) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi),GO:0060070; GO:0030154; GO:0005911; GO:0034109; GO:0016021; GO:0030336; GO:0008285; GO:0005886; GO:0034394; GO:0004725,canonical Wnt receptor signaling pathway; cell differentiation; cell-cell junction; homotypic cell-cell adhesion; integral to membrane; negative regulation of cell migration; negative regulation of cell proliferation; plasma membrane; protein localization to cell surface; protein tyrosine phosphatase activity,PF00041;PF00629;PF00102;,,,,,,,,,PTPRU_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; homotypic cell-cell adhesion [GO:0034109]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; organ regeneration [GO:0031100]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; response to glucocorticoid [GO:0051384]; single organismal cell-cell adhesion [GO:0016337] comp150596_c0_seq1,298,46.9799,0.37375421,4,7,,4.00E-37,Q9ES34,Ubiquitin-protein ligase E3B (EC 6.3.2.-),Ubiquitin-protein ligase E3B (EC 6.3.2.-),GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;PF00612;,2.00E-44,CHOYP_LOC659339.2.2,,,,,,,UBE3B_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp150606_c0_seq1,346,46.2428,0.71603773,0,23,,2.00E-24,Q497B2,Transmembrane protein 45B,Transmembrane protein 45B,GO:0016021,integral to membrane,PF04819;,8.00E-12,CHOYP_TM45B.1.1,,,,,,,TM45B_RAT,Rattus norvegicus (Rat), comp150615_c0_seq1,548,43.4307,0.58416879,24,0,,5.00E-14,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp150620_c0_seq1,330,45.4545,0.7216636,13,2,,8.00E-41,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp150625_c0_seq1,260,38.0769,0.53266094,4,5,,3.00E-09,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp15068_c0_seq1,285,47.7193,1.00023089,3,0,,1.00E-17,Q149M9,NACHT and WD repeat domain-containing protein 1,NACHT domain- and WD repeat-containing protein 1,GO:0005524,ATP binding,PF12894;PF00400;,5.00E-45,CHOYP_LOC100744637.1.1,,,,,,,NWD1_HUMAN,Homo sapiens (Human), comp150699_c0_seq1,623,45.1043,0.31620635,28,0,,6.00E-96,Q9R1D7,Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1),GO:0005086; GO:0032012,ARF guanyl-nucleotide exchange factor activity; regulation of ARF protein signal transduction,PF01369;PF12783;,2.00E-105,CHOYP_LOC579332.1.1,,,,,,,GBF1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] comp150703_c0_seq1,287,36.5854,0.41800217,7,8,,3.00E-10,Q7YU29,"Dystrophin, isoform E (Protein detached)","Dystrophin, isoform E (Protein detached)",GO:0003779; GO:0005509; GO:0005737; GO:0005856; GO:0016010; GO:0030010; GO:0008586; GO:0007474; GO:0046716; GO:0007517; GO:0007274; GO:0046928; GO:0048172; GO:0042383; GO:0005198; GO:0045202; GO:0008270,actin binding; calcium ion binding; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; establishment of cell polarity; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; muscle cell cellular homeostasis; muscle organ development; neuromuscular synaptic transmission; regulation of neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity; sarcolemma; structural molecule activity; synapse; zinc ion binding,PF09068;PF09069;PF00569;,2.00E-17,CHOYP_UTRO.1.1,,,,,,,DMDE_DROME,Drosophila melanogaster (Fruit fly),establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172] comp150708_c0_seq1,249,44.9799,0.64788865,0,14,,4.00E-11,P34147,Rho-related protein racA,Rho-related protein racA,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00651;PF00071;,,,,,,,,,RACA_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp150710_c0_seq1,473,48.8372,0.68916745,18,0,,1.00E-37,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp150712_c0_seq1,376,31.383,0.54924631,5,8,,4.00E-15,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,,,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp150714_c0_seq1,262,48.4733,0.40712667,5,6,,5.00E-27,Q8MLY8,40S ribosomal protein S8,40S ribosomal protein S8,GO:0022627; GO:0000462; GO:0022008; GO:0003735; GO:0006414,"cytosolic small ribosomal subunit; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neurogenesis; structural constituent of ribosome; translational elongation",PF01201;,6.00E-88,CHOYP_RS8.14.14,2.00E-16,ruditapes_lrc38534,,,,,RS8_DROME,Drosophila melanogaster (Fruit fly),"larval lymph gland hemopoiesis [GO:0035167]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; neurogenesis [GO:0022008]; translation [GO:0006412]" comp150724_c0_seq1,289,48.4429,0.54161263,4,13,,3.00E-14,Q6UXC1,Apical endosomal glycoprotein (MAM domain-containing protein 4),Apical endosomal glycoprotein (MAM domain-containing protein 4),GO:0016021; GO:0015031,integral to membrane; protein transport,PF00057;PF00629;,8.00E-24,CHOYP_LOC580670.1.6,,,,,,,AEGP_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp150725_c0_seq1,389,46.0154,0.51114361,5,11,,3.00E-22,E7F6F9,Kelch-like protein 3,Kelch-like protein 3,GO:0031463; GO:0005856; GO:0005829; GO:0072156; GO:0050801; GO:0070936; GO:0042787; GO:0070294,Cul3-RING ubiquitin ligase complex; cytoskeleton; cytosol; distal tubule morphogenesis; ion homeostasis; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; renal sodium ion absorption,PF07707;PF00651;PF01344;,1.00E-47,CHOYP_LOC100368146.1.1,,,,,,,KLHL3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294] comp150737_c0_seq1,209,41.1483,0.58334669,6,2,,5.00E-11,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp150757_c0_seq1,300,43.3333,0.14279096,11,6,,5.00E-26,Q9H2Y9,Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15),Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15),GO:0016021; GO:0005886; GO:0005215,integral to membrane; plasma membrane; transporter activity,PF07648;PF03137;,4.00E-59,CHOYP_MYSP.9.9,,,,,,,SO5A1_HUMAN,Homo sapiens (Human),sodium-independent organic anion transport [GO:0043252] comp150759_c0_seq1,226,61.0619,1.19199981,0,16,,8.00E-43,Q6A830,Lipoprotein LpqB,Lipoprotein LpqB,GO:0005886,plasma membrane,PF10646;PF10647;,,,,,,,,,LPQB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp150764_c0_seq1,320,46.25,0.87946064,15,0,,1.00E-09,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp150786_c0_seq1,222,45.045,0.89524097,1,12,,2.00E-12,O95279,Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2),Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2),GO:0007588; GO:0005887; GO:0005267; GO:0005244,excretion; integral to plasma membrane; potassium channel activity; voltage-gated ion channel activity,PF07885;,,,,,,,,,KCNK5_HUMAN,Homo sapiens (Human),excretion [GO:0007588]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] comp150795_c0_seq1,205,45.3659,0.48312594,0,8,,5.00E-11,A8MT65,Zinc finger protein 891,Zinc finger protein 891,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN891_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp150805_c0_seq1,227,40.9692,0.46722218,2,9,,1.00E-12,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp150814_c0_seq1,233,41.6309,0.88637996,4,7,,5.00E-16,Q7NDG8,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,4.00E-13,CHOYP_LOC100706374.1.1,,,,,,,DNAJ_GLOVI,Gloeobacter violaceus (strain PCC 7421),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp150821_c0_seq1,265,46.0377,0.78975484,5,11,,8.00E-09,Q6R5J2,Protein dispatched homolog 1 (Protein chameleon),Protein dispatched homolog 1 (Protein chameleon),GO:0021984; GO:0009952; GO:0008015; GO:0048701; GO:0008158; GO:0048839; GO:0016021; GO:0042694; GO:0031290; GO:0007519; GO:0007224,adenohypophysis development; anterior/posterior pattern specification; blood circulation; embryonic cranial skeleton morphogenesis; hedgehog receptor activity; inner ear development; integral to membrane; muscle cell fate specification; retinal ganglion cell axon guidance; skeletal muscle tissue development; smoothened signaling pathway,PF02460;,,,,,,,,,DISP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),adenohypophysis development [GO:0021984]; anterior/posterior pattern specification [GO:0009952]; blood circulation [GO:0008015]; embryonic cranial skeleton morphogenesis [GO:0048701]; inner ear development [GO:0048839]; muscle cell fate specification [GO:0042694]; organ morphogenesis [GO:0009887]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle tissue development [GO:0007519]; smoothened signaling pathway [GO:0007224] comp150824_c0_seq1,211,46.9194,1.0435017,3,7,,3.00E-08,P12260,Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain) (Fragment),Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain) (Fragment),GO:0007596; GO:0005737; GO:0005576; GO:0018149; GO:0003810,blood coagulation; cytoplasm; extracellular region; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00868;,,,,,,,,,F13A_BOVIN,Bos taurus (Bovine),blood coagulation [GO:0007596]; peptide cross-linking [GO:0018149] comp150825_c0_seq1,406,38.9163,1.11310199,8,8,,6.00E-29,A1KZ92,Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1),Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1),GO:0005737; GO:0004519; GO:0005615; GO:0020037; GO:0042744; GO:0046872; GO:0090305; GO:0004601,cytoplasm; endonuclease activity; extracellular space; heme binding; hydrogen peroxide catabolic process; metal ion binding; nucleic acid phosphodiester bond hydrolysis; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDNL_HUMAN,Homo sapiens (Human),hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979] comp150846_c0_seq1,404,31.6832,0.49547649,14,13,,,,,,,,,8.00E-32,CHOYP_LOC100708199.6.6,,,,,,,,, comp150860_c0_seq1,306,43.4641,1.02042875,4,11,,6.00E-20,Q5RC26,Fibulin-5 (FIBL-5),Fibulin-5 (FIBL-5),GO:0005509; GO:0007155; GO:0005576,calcium ion binding; cell adhesion; extracellular region,PF12662;PF07645;,,,,,,,,,FBLN5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell adhesion [GO:0007155]; elastic fiber assembly [GO:0048251] comp150864_c0_seq1,229,41.9214,1.03465761,2,8,,1.00E-06,Q00719,O-methyltransferase MdmC (EC 2.1.1.-),O-methyltransferase MdmC (EC 2.1.1.-),GO:0008171; GO:0017000; GO:0046872,O-methyltransferase activity; antibiotic biosynthetic process; metal ion binding,PF01596;,,,5.00E-23,ruditapes_c16088,,,,,MDMC_STRMY,Streptomyces mycarofaciens,antibiotic biosynthetic process [GO:0017000] comp150868_c0_seq1,241,47.7178,0.36622907,12,0,,2.00E-12,Q5T011,Protein SZT2 (Seizure threshold 2 protein homolog),Protein SZT2 (Seizure threshold 2 protein homolog),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp150881_c0_seq1,244,44.6721,0.49831345,8,0,,1.00E-08,Q96BY7,Autophagy-related protein 2 homolog B,Autophagy-related protein 2 homolog B,GO:0006914; GO:0005811; GO:0034045,autophagy; lipid particle; pre-autophagosomal structure membrane,PF13329;PF09333;PF12624;,,,,,,,,,ATG2B_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp150883_c0_seq1,290,47.2414,0.81884091,7,12,,6.00E-18,P78381,UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),GO:0000139; GO:0005459; GO:0006012; GO:0016021; GO:0005634; GO:0005351,Golgi membrane; UDP-galactose transmembrane transporter activity; galactose metabolic process; integral to membrane; nucleus; sugar:hydrogen symporter activity,PF04142;,,,,,,,,,S35A2_HUMAN,Homo sapiens (Human),galactose metabolic process [GO:0006012]; UDP-galactose transport [GO:0015785] comp150906_c0_seq1,265,45.6604,0.59046346,8,3,,2.00E-37,Q62865,"cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)","cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)",GO:0004115; GO:0030552; GO:0006198; GO:0019933; GO:0004119; GO:0019934; GO:0071321; GO:0071560; GO:0005829; GO:0016101; GO:0016021; GO:0046872; GO:0043066; GO:0043116; GO:0001556; GO:0060282; GO:0043117; GO:0040020; GO:0051591; GO:0042493,"3',5'-cyclic-AMP phosphodiesterase activity; cAMP binding; cAMP catabolic process; cAMP-mediated signaling; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; cGMP-mediated signaling; cellular response to cGMP; cellular response to transforming growth factor beta stimulus; cytosol; diterpenoid metabolic process; integral to membrane; metal ion binding; negative regulation of apoptotic process; negative regulation of vascular permeability; oocyte maturation; positive regulation of oocyte development; positive regulation of vascular permeability; regulation of meiosis; response to cAMP; response to drug",PF00233;,1.00E-52,CHOYP_PDE3A.3.3,,,,,,,PDE3A_RAT,Rattus norvegicus (Rat),cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; diterpenoid metabolic process [GO:0016101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; response to cAMP [GO:0051591]; response to drug [GO:0042493] comp150919_c0_seq1,332,44.5783,0.64199541,7,0,,3.00E-22,Q61555,Fibrillin-2,Fibrillin-2 [Cleaved into: Fibrillin-2 C-terminal peptide],GO:0060346; GO:0005509; GO:0030326; GO:0005201; GO:0001527; GO:0030501; GO:0045669; GO:0035583,bone trabecula formation; calcium ion binding; embryonic limb morphogenesis; extracellular matrix structural constituent; microfibril; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; sequestering of TGFbeta in extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN2_MOUSE,Mus musculus (Mouse),bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; sequestering of TGFbeta in extracellular matrix [GO:0035583] comp150945_c0_seq1,583,45.4545,0.43274181,15,12,,2.00E-21,Q9Y2I7,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),GO:0000285; GO:0016308; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0045121; GO:0046872; GO:0032288; GO:0048471; GO:0043813; GO:0034504; GO:0042147; GO:0044281,"1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; membrane raft; metal ion binding; myelin assembly; perinuclear region of cytoplasm; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; protein localization to nucleus; retrograde transport, endosome to Golgi; small molecule metabolic process",PF00118;PF00610;PF01363;PF01504;,,,,,,,,,FYV1_HUMAN,Homo sapiens (Human),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp150947_c0_seq1,301,41.5282,0.38958118,3,8,,,,,,,,,1.00E-15,CHOYP_LOC100858674.1.1,,,,,,,,, comp150955_c0_seq1,251,36.255,1.10205831,0,11,,1.00E-16,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp150959_c0_seq1,337,42.1365,0.47084992,8,11,,2.00E-38,Q99KY4,Cyclin-G-associated kinase (EC 2.7.11.1),Cyclin-G-associated kinase (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0007049; GO:0005925; GO:0048471; GO:0004674,ATP binding; Golgi apparatus; cell cycle; focal adhesion; perinuclear region of cytoplasm; protein serine/threonine kinase activity,PF00226;PF00069;PF10409;,8.00E-31,CHOYP_GAK.1.1,,,,,,,GAK_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell development [GO:0048468]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; epidermal cell differentiation [GO:0009913]; establishment of skin barrier [GO:0061436]; forebrain morphogenesis [GO:0048853]; Golgi organization [GO:0007030]; intrahepatic bile duct development [GO:0035622]; negative regulation of neuron projection development [GO:0010977]; positive regulation of neural precursor cell proliferation [GO:2000179] comp150963_c0_seq1,295,48.1356,0.60756035,5,11,,2.00E-28,Q4PKH3,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0016021; GO:0005765; GO:0005247,ATP binding; antiporter activity; integral to membrane; lysosomal membrane; voltage-gated chloride channel activity,PF00571;PF00654;,3.00E-35,CHOYP_CLCN7.3.3,,,,,,,CLCN7_BOVIN,Bos taurus (Bovine),chloride transmembrane transport [GO:1902476] comp150965_c0_seq1,228,41.2281,0.74214391,2,7,,9.00E-33,P51793,H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4),H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4),GO:0005524; GO:0015297; GO:0031901; GO:0010008; GO:0016021; GO:0031902; GO:0005247,ATP binding; antiporter activity; early endosome membrane; endosome membrane; integral to membrane; late endosome membrane; voltage-gated chloride channel activity,PF00571;PF00654;,4.00E-32,CHOYP_CLCN3.1.1,,,,,,,CLCN4_HUMAN,Homo sapiens (Human),chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transport [GO:0006810] comp150979_c0_seq1,563,39.4316,0.36983723,16,4,,6.00E-52,Q96LD8,"Sentrin-specific protease 8 (EC 3.4.22.68) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)","Sentrin-specific protease 8 (EC 3.4.22.68) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)",GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF02902;,3.00E-38,CHOYP_BRAFLDRAFT_221105.2.2,8.00E-76,ruditapes_c11343,,,,,SENP8_HUMAN,Homo sapiens (Human), comp150989_c0_seq1,230,43.4783,1.7584467,9,0,,,,,,,,,8.00E-16,CHOYP_LOC100744637.1.1,,,,,,,,, comp150992_c0_seq1,218,44.0367,1.140649,1,14,,8.00E-11,Q7A5L8,L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase),GO:0004794; GO:0070689; GO:0000166; GO:0030170,L-threonine ammonia-lyase activity; L-threonine catabolic process to propionate; nucleotide binding; pyridoxal phosphate binding,PF00291;,,,,,,,,,TDCB_STAAN,Staphylococcus aureus (strain N315),L-threonine catabolic process to propionate [GO:0070689] comp151011_c0_seq1,262,46.1832,0.07330096,2,13,,2.00E-14,Q10725,Phenylserine dehydratase (EC 4.2.1.-),Phenylserine dehydratase (EC 4.2.1.-),GO:0016829,lyase activity,PF00291;,,,,,,,,,FSDH_BURPI,Ralstonia pickettii (Burkholderia pickettii), comp151023_c0_seq1,290,45.1724,0.1360465,4,7,,4.00E-32,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp151031_c0_seq1,327,50.1529,0.43961692,8,0,,1.00E-33,P70475,Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1),Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1),GO:0001105; GO:0030154; GO:0007399; GO:0005634; GO:0044323; GO:0003700; GO:0008270,RNA polymerase II transcription coactivator activity; cell differentiation; nervous system development; nucleus; retinoic acid-responsive element binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF08474;PF01530;,7.00E-25,CHOYP_LOC100313656.1.1,,,,,,,MYT1L_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp151035_c0_seq1,504,45.4365,0.74219042,29,0,,8.00E-35,O35516,Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],GO:0007219; GO:0060413; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0061073; GO:0005829; GO:0030326; GO:0005576; GO:0072104; GO:0072015; GO:0001947; GO:0006959; GO:0001701; GO:0002437; GO:0005887; GO:0072602; GO:0070986; GO:0002011; GO:0008285; GO:0000122; GO:0005654; GO:0060674; GO:0030513; GO:0046579; GO:0043065; GO:0008284; GO:0045672; GO:0072014; GO:0006351; GO:0042060,"Notch signaling pathway; atrial septum morphogenesis; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; ciliary body morphogenesis; cytosol; embryonic limb morphogenesis; extracellular region; glomerular capillary formation; glomerular visceral epithelial cell development; heart looping; humoral immune response; in utero embryonic development; inflammatory response to antigenic stimulus; integral to plasma membrane; interleukin-4 secretion; left/right axis specification; morphogenesis of an epithelial sheet; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; placenta blood vessel development; positive regulation of BMP signaling pathway; positive regulation of Ras protein signal transduction; positive regulation of apoptotic process; positive regulation of cell proliferation; positive regulation of osteoclast differentiation; proximal tubule development; transcription, DNA-dependent; wound healing",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_MOUSE,Mus musculus (Mouse),"atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]" comp151036_c0_seq1,360,42.2222,0.76067312,18,0,,,,,,,,,2.00E-13,CHOYP_ISCW_ISCW014636.1.2,,,,,,,,, comp151053_c0_seq1,351,56.1254,1.38154395,0,14,,1.00E-21,P0CAV7,Chromosome partitioning protein ParA,Chromosome partitioning protein ParA,GO:0005524; GO:0007059,ATP binding; chromosome segregation,PF13614;,,,,,,,,,PARA_CAUCR,Caulobacter crescentus (strain ATCC 19089 / CB15),chromosome segregation [GO:0007059] comp151056_c0_seq1,285,44.2105,0.98543487,0,16,,2.00E-10,Q05585,Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (CD antigen CD204),Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (CD antigen CD204),GO:0005581; GO:0016021; GO:0034362; GO:0005044,collagen; integral to membrane; low-density lipoprotein particle; scavenger receptor activity,PF01391;PF03523;PF00530;,,,,,,,,,MSRE_RABIT,Oryctolagus cuniculus (Rabbit), comp151060_c0_seq1,387,42.6357,0.98831945,6,11,,7.00E-28,P18172,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding,PF05199;PF00732;,,,,,,,,,DHGL_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly), comp151063_c0_seq1,233,43.7768,0.3604225,5,10,,6.00E-23,Q5UQ88,Probable ubiquitin-conjugating enzyme E2 R521 (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Probable ubiquitin-conjugating enzyme E2 R521 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R521) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0042262; GO:0016021; GO:0004842,ATP binding; DNA protection; integral to membrane; ubiquitin-protein ligase activity,PF00179;,7.00E-23,CHOYP_BRAFLDRAFT_85147.1.1,,,,,,,UBC3_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),protein ubiquitination [GO:0016567] comp151088_c0_seq1,201,73.1343,1.01077372,0,14,,6.00E-39,A1W6V9,tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC (tRNA mnm(5)s(2)U biosynthesis bifunctional protein) [Includes: tRNA (mnm(5)s(2)U34)-methyltransferase (EC 2.1.1.61); FAD-dependent cmnm(5)s(2)U34 oxidoreductase (EC 1.5.-.-)],tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC (tRNA mnm(5)s(2)U biosynthesis bifunctional protein) [Includes: tRNA (mnm(5)s(2)U34)-methyltransferase (EC 2.1.1.61); FAD-dependent cmnm(5)s(2)U34 oxidoreductase (EC 1.5.-.-)],GO:0005737; GO:0050660; GO:0016645; GO:0004808; GO:0002097,"cytoplasm; flavin adenine dinucleotide binding; oxidoreductase activity, acting on the CH-NH group of donors; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity; tRNA wobble base modification",PF01266;PF05430;,,,,,,,,,MNMC_ACISJ,Acidovorax sp. (strain JS42),tRNA wobble base modification [GO:0002097] comp151089_c0_seq1,245,45.3061,0.32540225,8,8,,9.00E-25,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,4.00E-26,CHOYP_LOC763281.1.1,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp151097_c0_seq1,299,36.4548,0.50539649,6,10,,5.00E-12,Q8IYB9,Zinc finger protein 595,Zinc finger protein 595,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN595_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp151115_c0_seq1,213,46.4789,1.06646869,1,8,,1.00E-06,P41984,Muscarinic acetylcholine receptor M3,Muscarinic acetylcholine receptor M3,GO:0016907; GO:0007213; GO:0016323; GO:0030054; GO:0005887; GO:0045987; GO:0045211; GO:0046541; GO:0006939,G-protein coupled acetylcholine receptor activity; G-protein coupled acetylcholine receptor signaling pathway; basolateral plasma membrane; cell junction; integral to plasma membrane; positive regulation of smooth muscle contraction; postsynaptic membrane; saliva secretion; smooth muscle contraction,PF00001;,,,,,,,,,ACM3_BOVIN,Bos taurus (Bovine),"adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway [GO:0007197]; phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of vascular smooth muscle contraction [GO:0003056]; saliva secretion [GO:0046541]; smooth muscle contraction [GO:0006939]; synaptic transmission, cholinergic [GO:0007271]" comp151145_c0_seq1,462,40.9091,0.37167605,9,12,,3.00E-29,P49641,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0004572; GO:0043687; GO:0018279; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; post-translational protein modification; protein N-linked glycosylation via asparagine; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A2_HUMAN,Homo sapiens (Human),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp151149_c0_seq1,251,62.1514,1.07764868,1,13,,1.00E-19,Q70AC7,Methylmalonyl-CoA carboxyltransferase 5S subunit (EC 2.1.3.1) (Transcarboxylase 5S subunit),Methylmalonyl-CoA carboxyltransferase 5S subunit (EC 2.1.3.1) (Transcarboxylase 5S subunit),GO:0008152; GO:0046872; GO:0047154,metabolic process; metal ion binding; methylmalonyl-CoA carboxytransferase activity,PF00682;PF02436;,,,,,,,,,5S_PROFR,Propionibacterium freudenreichii subsp. shermanii, comp151159_c0_seq1,237,67.9325,1.18848765,0,9,,8.00E-15,O08394,Probable bifunctional P-450/NADPH-P450 reductase 1 [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)],Bifunctional cytochrome P450/NADPH--P450 reductase 1 (CYP102A2) (Fatty acid hydroxylase CypD) (Flavocytochrome P450 102A2) [Includes: Cytochrome P450 102A2 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)],GO:0010181; GO:0003958; GO:0070330; GO:0005737; GO:0020037; GO:0005506,FMN binding; NADPH-hemoprotein reductase activity; aromatase activity; cytoplasm; heme binding; iron ion binding,PF00667;PF00258;PF00175;PF00067;,,,,,,,,,CYPD_BACSU,Bacillus subtilis (strain 168),fatty acid oxidation [GO:0019395] comp151162_c0_seq1,258,46.5116,0.15097866,4,5,,3.00E-14,Q5ZMR9,Exportin-4,Exportin-4,GO:0005737; GO:0005634; GO:0015031,cytoplasm; nucleus; protein transport,PF08767;,1.00E-14,CHOYP_XPO4.1.1,,,,,,,XPO4_CHICK,Gallus gallus (Chicken),protein export from nucleus [GO:0006611] comp151167_c0_seq1,210,59.0476,1.18082746,2,2,,,,,,,,,5.00E-24,CHOYP_contig_007479,,,,,,,,, comp151170_c0_seq1,216,49.0741,0.23250498,6,5,,2.00E-19,Q2KHT3,Protein CLEC16A,Protein CLEC16A (C-type lectin domain family 16 member A),,,PF09758;,1.00E-25,CHOYP_LOC410511.2.2,,,,,,,CL16A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914] comp151196_c0_seq1,288,36.4583,1.26755914,0,16,,3.00E-08,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp151207_c0_seq1,210,43.3333,0.88194267,11,0,,1.00E-20,Q6VNB8,"WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)","WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)",GO:0005545; GO:0005776; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; autophagic vacuole; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,1.00E-12,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_MOUSE,Mus musculus (Mouse),aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239] comp151208_c0_seq1,210,67.619,0.77196872,3,7,,9.00E-08,A7Z809,2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase),2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (o-succinylbenzoyl-CoA synthetase) (OSB-CoA synthetase),GO:0005524; GO:0009234; GO:0008756,ATP binding; menaquinone biosynthetic process; o-succinylbenzoate-CoA ligase activity,PF00501;PF13193;,,,,,,,,,MENE_BACA2,Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum),menaquinone biosynthetic process [GO:0009234] comp151212_c0_seq1,307,40.0651,0.91321724,3,9,,1.00E-22,Q5KQT7,Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1),Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1),GO:0009308; GO:0070330; GO:0017144; GO:0005789; GO:0020037; GO:0046483; GO:0050665; GO:0005506; GO:0009636; GO:0009404; GO:0070576,amine metabolic process; aromatase activity; drug metabolic process; endoplasmic reticulum membrane; heme binding; heterocycle metabolic process; hydrogen peroxide biosynthetic process; iron ion binding; response to toxic substance; toxin metabolic process; vitamin D 24-hydroxylase activity,PF00067;,,,,,,,,,CP1A1_FELCA,Felis catus (Cat) (Felis silvestris catus),amine metabolic process [GO:0009308]; cellular response to organic cyclic compound [GO:0071407]; drug metabolic process [GO:0017144]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; response to toxic substance [GO:0009636]; toxin metabolic process [GO:0009404] comp151221_c0_seq1,207,40.5797,0.24257126,1,6,,8.00E-10,Q9H1Q7,PC-esterase domain-containing protein 1A (Protein FAM113A) (Sarcoma antigen NY-SAR-23),PC-esterase domain-containing protein 1A (Protein FAM113A) (Sarcoma antigen NY-SAR-23),,,PF13839;,,,,,,,,,PED1A_HUMAN,Homo sapiens (Human), comp151222_c0_seq1,376,55.3191,1.01542466,0,18,,3.00E-08,Q9KEF0,L-arabinose transport system permease protein AraP,L-arabinose transport system permease protein AraP,GO:0008643; GO:0016021; GO:0005886; GO:0005215,carbohydrate transport; integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,ARAP_BACHD,Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125),carbohydrate transport [GO:0008643] comp151227_c0_seq1,294,55.7823,0.93257138,0,13,,3.00E-15,Q9KL06,Maltose transport system permease protein MalF,Maltose transport system permease protein MalF,GO:0016021; GO:0015423; GO:0005886,integral to membrane; maltose-transporting ATPase activity; plasma membrane,PF00528;PF14785;,,,,,,,,,MALF_VIBCH,Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961),maltose transport [GO:0015768] comp15122_c0_seq1,210,42.381,0.96202789,3,0,,9.00E-07,P52181,Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase-2) (TGase-2),Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase-2) (TGase-2),GO:0046872; GO:0018149; GO:0003810,metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,TGM2_PAGMA,Pagrus major (Red sea bream) (Chrysophrys major),peptide cross-linking [GO:0018149] comp151239_c0_seq1,291,39.5189,0.35653657,8,0,,9.00E-08,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp151241_c0_seq1,205,37.561,0.99313658,2,7,,6.00E-06,Q1PSW8,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:2000637; GO:0051865; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,,,,,,,,,LIN41_MOUSE,Mus musculus (Mouse),3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] comp151246_c0_seq1,242,33.0579,0.30394515,3,6,,7.00E-13,Q5EZ72,Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase),Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase),GO:0016021; GO:0004767,integral to membrane; sphingomyelin phosphodiesterase activity,PF01663;,,,,,,,,,ENPP7_RAT,Rattus norvegicus (Rat),sphingomyelin catabolic process [GO:0006685] comp151250_c0_seq1,252,48.0159,1.10602835,0,14,,6.00E-12,P86733,BPTI/Kunitz domain-containing protein (Fragment),BPTI/Kunitz domain-containing protein (Fragment),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,KCP_HALAI,Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone), comp151263_c0_seq1,438,45.6621,1.10147102,4,15,,7.00E-30,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp151277_c0_seq1,252,46.8254,0.07286981,7,9,,1.00E-29,Q7TQP6,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF12796;PF07714;,4.00E-33,CHOYP_LOC576866.1.1,,,,,,,TNI3K_RAT,Rattus norvegicus (Rat),bundle of His cell to Purkinje myocyte communication [GO:0086069]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027] comp151285_c0_seq1,283,51.5901,0.48409695,4,9,,8.00E-35,O54967,Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2),Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2),GO:0005524; GO:0005912; GO:0030424; GO:0030136; GO:0005905; GO:0030659; GO:0030425; GO:0006897; GO:0005768; GO:0030426; GO:0046872; GO:0043025; GO:0004715; GO:0005634; GO:0018108; GO:0005886; GO:0004674,ATP binding; adherens junction; axon; clathrin-coated vesicle; coated pit; cytoplasmic vesicle membrane; dendrite; endocytosis; endosome; growth cone; metal ion binding; neuronal cell body; non-membrane spanning protein tyrosine kinase activity; nucleus; peptidyl-tyrosine phosphorylation; plasma membrane; protein serine/threonine kinase activity,PF09027;PF11555;PF07714;PF14604;,3.00E-23,CHOYP_TNK2.1.1,,,,,,,ACK1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell migration [GO:0016477]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of clathrin-mediated endocytosis [GO:2000369]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp151289_c0_seq1,218,45.4128,0.73676908,2,9,,1.00E-07,Q9WTX4,"Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Cleaved into: Neuregulin-4 (NRG-4)]","Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Cleaved into: Neuregulin-4 (NRG-4)]",GO:0005576; GO:0016021; GO:0005886,extracellular region; integral to membrane; plasma membrane,,,,,,,,,,NRG4_MOUSE,Mus musculus (Mouse),animal organ development [GO:0048513]; intracellular signal transduction [GO:0035556] comp151292_c0_seq1,405,45.679,0.86752666,15,5,,6.00E-22,P98157,Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),GO:0005509; GO:0005905; GO:0006897; GO:0016021,calcium ion binding; coated pit; endocytosis; integral to membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp151305_c0_seq1,413,42.3729,0.32445331,10,7,,2.00E-26,Q25BN1,Endoribonuclease Dicer (EC 3.1.26.-),Endoribonuclease Dicer (EC 3.1.26.3),GO:0005524; GO:0008026; GO:0016442; GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0031054; GO:0030422; GO:0004525; GO:0030423,ATP binding; ATP-dependent helicase activity; RISC complex; RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; pre-miRNA processing; production of siRNA involved in RNA interference; ribonuclease III activity; targeting of mRNA for destruction involved in RNA interference,PF00270;PF03368;PF00271;PF02170;PF00636;,,,,,,,,,DICER_CHICK,Gallus gallus (Chicken),apoptotic DNA fragmentation [GO:0006309]; pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423] comp151313_c0_seq1,277,43.3213,0.23972718,7,2,,3.00E-24,P53396,ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme),ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme),GO:0005524; GO:0006200; GO:0003878; GO:0044262; GO:0009346; GO:0006101; GO:0015936; GO:0048037; GO:0005829; GO:0006112; GO:0035338; GO:0046872; GO:0005739; GO:0005634; GO:0005886; GO:0031325; GO:0004775; GO:0019432,ATP binding; ATP catabolic process; ATP citrate synthase activity; cellular carbohydrate metabolic process; citrate lyase complex; citrate metabolic process; coenzyme A metabolic process; cofactor binding; cytosol; energy reserve metabolic process; long-chain fatty-acyl-CoA biosynthetic process; metal ion binding; mitochondrion; nucleus; plasma membrane; positive regulation of cellular metabolic process; succinate-CoA ligase (ADP-forming) activity; triglyceride biosynthetic process,PF16114;PF00285;PF02629;PF00549;,2.00E-24,CHOYP_ACLY.1.1,,,,,,,ACLY_HUMAN,Homo sapiens (Human),acetyl-CoA biosynthetic process [GO:0006085]; cholesterol biosynthetic process [GO:0006695]; citrate metabolic process [GO:0006101]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; oxaloacetate metabolic process [GO:0006107]; positive regulation of cellular metabolic process [GO:0031325] comp151314_c0_seq1,515,40.1942,0.53196077,13,5,,2.00E-49,Q2HJ95,Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 6) (DHHC-6),Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 6) (DHHC-6),GO:0005789; GO:0016021; GO:0016746; GO:0008270,"endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF07653;PF01529;,5.00E-29,CHOYP_LOC100373598.1.1,,,,,,,ZDHC6_BOVIN,Bos taurus (Bovine),protein palmitoylation [GO:0018345] comp151328_c0_seq1,214,38.785,0.5212235,3,0,,4.00E-13,Q9H2M9,Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0006886; GO:0005886; GO:0046982,GTPase activator activity; cytoplasm; intracellular protein transport; plasma membrane; protein heterodimerization activity,PF14656;PF14655;,,,,,,,,,RBGPR_HUMAN,Homo sapiens (Human),establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp151330_c0_seq1,210,56.6667,0.71567479,0,11,,6.00E-30,Q42687,"ATP synthase delta chain, chloroplastic (F-ATPase delta chain)","ATP synthase delta chain, chloroplastic (F-ATPase delta chain)",GO:0015986; GO:0009535; GO:0046933; GO:0045261,"ATP synthesis coupled proton transport; chloroplast thylakoid membrane; proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATP synthase complex, catalytic core F(1)",PF00213;,,,,,,,,,ATPD_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),ATP synthesis coupled proton transport [GO:0015986] comp151344_c0_seq1,305,46.2295,0.49675859,4,5,,7.00E-19,Q8UWF0,High-affinity choline transporter 1,High-affinity choline transporter 1,GO:0008292; GO:0015220; GO:0016021; GO:0006814; GO:0015293,acetylcholine biosynthetic process; choline transmembrane transporter activity; integral to membrane; sodium ion transport; symporter activity,PF00474;,4.00E-27,CHOYP_BRAFLDRAFT_207989.1.1,,,,,,,SC5A7_TORMA,Torpedo marmorata (Marbled electric ray),acetylcholine biosynthetic process [GO:0008292]; sodium ion transport [GO:0006814] comp151371_c0_seq1,272,40.0735,0.36768174,6,5,,2.00E-06,Q91WF7,"Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)","Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)",GO:0008219; GO:0010008; GO:0007626; GO:0032288; GO:0031642; GO:0048666; GO:0046488; GO:0042578; GO:0043473; GO:0007033,cell death; endosome membrane; locomotory behavior; myelin assembly; negative regulation of myelination; neuron development; phosphatidylinositol metabolic process; phosphoric ester hydrolase activity; pigmentation; vacuole organization,PF02383;,,,,,,,,,FIG4_MOUSE,Mus musculus (Mouse),locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol metabolic process [GO:0046488]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] comp151375_c0_seq1,220,44.5455,0.55435928,1,13,,5.00E-10,Q90678,Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase),Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase),GO:0003847; GO:0005615; GO:0016042,1-alkyl-2-acetylglycerophosphocholine esterase activity; extracellular space; lipid catabolic process,PF03403;,,,,,,,,,PAFA_CHICK,Gallus gallus (Chicken),lipid catabolic process [GO:0016042] comp151383_c0_seq1,320,44.6875,0.64174957,3,11,,6.00E-12,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp151390_c0_seq1,372,37.6344,0.6091083,9,7,,5.00E-27,Q9GV77,Extracellular matrix protein 3 (FREM2 homolog),Extracellular matrix protein 3 (FREM2 homolog),GO:0005509; GO:0007154; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; cell communication; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF03160;,,,,,,,,,FREM2_LYTVA,Lytechinus variegatus (Green sea urchin) (Variegated urchin),cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp151391_c0_seq1,227,41.8502,0.31319289,5,6,,1.00E-06,O93209,Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (p42In)],Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)],GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0030430; GO:0042025; GO:0046872; GO:0090305; GO:0006508; GO:0004523; GO:0046718; GO:0075732; GO:0019012,DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; host cell cytoplasm; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; viral entry into host cell; viral penetration into host nucleus; virion,PF00075;PF00665;PF00078;PF03539;,,,,,,,,,POL_FFV,Feline foamy virus (FFV) (Feline syncytial virus),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] comp151397_c0_seq1,205,61.4634,1.30946416,1,8,,9.00E-08,P0AEM9,Cystine-binding periplasmic protein (CBP) (Protein FliY) (Sulfate starvation-induced protein 7) (SSI7),L-cystine-binding protein FliY (CBP) (Protein FliY) (Sulfate starvation-induced protein 7) (SSI7),GO:0030288; GO:0042597; GO:0005215,outer membrane-bounded periplasmic space; periplasmic space; transporter activity,PF00497;,,,,,,,,,FLIY_ECOLI,Escherichia coli (strain K12),cysteine transport [GO:0042883]; L-cystine transport [GO:0015811] comp151408_c0_seq1,218,41.7431,0.6524467,6,0,,5.00E-06,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp151410_c0_seq1,240,43.3333,0.80334728,2,7,,5.00E-18,Q8CIY2,Dual oxidase 1 (EC 1.11.1.-) (EC 1.6.3.1),Dual oxidase 1 (EC 1.11.1.-) (EC 1.6.3.1),GO:0016174; GO:0016324; GO:0005509; GO:0042335; GO:0019221; GO:0020037; GO:0042446; GO:0042744; GO:0016021; GO:0004601; GO:0051591; GO:0006590,NAD(P)H oxidase activity; apical plasma membrane; calcium ion binding; cuticle development; cytokine-mediated signaling pathway; heme binding; hormone biosynthetic process; hydrogen peroxide catabolic process; integral to membrane; peroxidase activity; response to cAMP; thyroid hormone generation,PF03098;PF00036;PF13499;PF08022;PF01794;PF08030;,,,,,,,,,DUOX1_RAT,Rattus norvegicus (Rat),cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide catabolic process [GO:0042744]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590] comp151412_c0_seq1,207,50.2415,0.31337831,2,6,,2.00E-10,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp151428_c0_seq1,296,45.9459,0.3977724,2,13,,2.00E-22,Q9JIW4,DNA-directed DNA/RNA polymerase mu (Pol Mu) (EC 2.7.7.7) (Terminal transferase),DNA-directed DNA/RNA polymerase mu (Pol Mu) (EC 2.7.7.7) (Terminal transferase),GO:0030183; GO:0003677; GO:0006310; GO:0006281; GO:0003887; GO:0046872; GO:0005634; GO:0016446,B cell differentiation; DNA binding; DNA recombination; DNA repair; DNA-directed DNA polymerase activity; metal ion binding; nucleus; somatic hypermutation of immunoglobulin genes,PF14792;PF14791;PF10391;PF14716;,,,,,,,,,DPOLM_MOUSE,Mus musculus (Mouse),B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp151445_c0_seq1,247,46.5587,0.37530882,1,13,,1.00E-21,P51815,Zinc finger protein 75D (Zinc finger protein 75) (Zinc finger protein 82),Zinc finger protein 75D (Zinc finger protein 75) (Zinc finger protein 82),GO:0003677; GO:0005634; GO:0006355; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF02023;PF00096;,,,,,,,,,ZN75D_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp151447_c0_seq1,415,41.4458,0.61871641,8,12,,1.00E-30,A6H7I3,Protein angel homolog 2,Protein angel homolog 2,,,PF03372;,,,,,,,,,ANGE2_BOVIN,Bos taurus (Bovine),3'-UTR-mediated mRNA stabilization [GO:0070935]; negative regulation of mitotic cell cycle [GO:0045930] comp151451_c0_seq1,309,41.1003,0.2371264,4,10,,6.00E-41,Q5F3L4,Protein DENND6A (DENN domain-containing protein 6A),Protein DENND6A (DENN domain-containing protein 6A),GO:0005085; GO:0055037,guanyl-nucleotide exchange factor activity; recycling endosome,PF09794;,3.00E-48,CHOYP_LOC100372051.1.1,,,,,,,F116A_CHICK,Gallus gallus (Chicken),positive regulation of GTPase activity [GO:0043547] comp151457_c0_seq1,335,55.2239,0.56140851,11,27,,,,,,,,,2.00E-19,CHOYP_contig_002261,,,,,,,,, comp151460_c0_seq1,307,45.6026,0.5095174,13,0,,3.00E-18,P32198,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0071398; GO:0042755; GO:0006635; GO:0006006; GO:0042802; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006810; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; cellular response to fatty acid; eating behavior; fatty acid beta-oxidation; glucose metabolic process; identical protein binding; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; transport; triglyceride metabolic process,PF00755;PF16484;,6.00E-19,CHOYP_LOC577934.1.1,,,,,,,CPT1A_RAT,Rattus norvegicus (Rat),carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641] comp151466_c0_seq1,266,42.4812,0.75757691,4,10,,2.00E-25,P12821,"Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]","Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]",GO:0003779; GO:0002005; GO:0002003; GO:0050482; GO:0001974; GO:0004180; GO:0044267; GO:0031404; GO:0008144; GO:0004175; GO:0005768; GO:0009897; GO:0005615; GO:0060218; GO:0042447; GO:0016021; GO:0001822; GO:0008237; GO:0032943; GO:0043171; GO:0008241; GO:0005886; GO:0006508; GO:0002019; GO:0014910; GO:0019229; GO:0042312; GO:0008270,actin binding; angiotensin catabolic process in blood; angiotensin maturation; arachidonic acid secretion; blood vessel remodeling; carboxypeptidase activity; cellular protein metabolic process; chloride ion binding; drug binding; endopeptidase activity; endosome; external side of plasma membrane; extracellular space; hematopoietic stem cell differentiation; hormone catabolic process; integral to membrane; kidney development; metallopeptidase activity; mononuclear cell proliferation; peptide catabolic process; peptidyl-dipeptidase activity; plasma membrane; proteolysis; regulation of renal output by angiotensin; regulation of smooth muscle cell migration; regulation of vasoconstriction; regulation of vasodilation; zinc ion binding,PF01401;,2.00E-19,CHOYP_ACE.3.4,,,,,,,ACE_HUMAN,Homo sapiens (Human),angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; beta-amyloid metabolic process [GO:0050435]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; regulation of vasodilation [GO:0042312]; spermatogenesis [GO:0007283] comp151469_c0_seq1,248,61.6935,0.85715679,0,13,,1.00E-35,Q6A6U0,Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (EC 2.7.8.7) (4'-phosphopantetheinyl transferase AcpS),Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (EC 2.7.8.7) (4'-phosphopantetheinyl transferase AcpS),GO:0005737; GO:0006633; GO:0008897; GO:0009059; GO:0000287,cytoplasm; fatty acid biosynthetic process; holo-[acyl-carrier-protein] synthase activity; macromolecule biosynthetic process; magnesium ion binding,PF01648;,,,,,,,,,ACPS_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),fatty acid biosynthetic process [GO:0006633] comp151487_c0_seq1,222,37.3874,0.38896138,0,7,,9.00E-17,Q28FF3,Major facilitator superfamily domain-containing protein 7-a,Major facilitator superfamily domain-containing protein 7-a,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,MFS7A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),transmembrane transport [GO:0055085] comp151498_c0_seq1,315,45.7143,0.82358488,7,7,,2.00E-24,O88281,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF12662;PF07645;PF00053;,,,,,,,,,MEGF6_RAT,Rattus norvegicus (Rat), comp151501_c0_seq1,202,65.3465,1.26555861,0,7,,4.00E-08,P0A900,Esterase YqiA (EC 3.1.-.-),Esterase YqiA (EC 3.1.-.-),GO:0004091,carboxylesterase activity,PF05728;,,,,,,,,,YQIA_SHIFL,Shigella flexneri, comp151506_c0_seq1,302,43.0464,0.78888439,6,4,,4.00E-22,P16067,Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),GO:0005524; GO:0005525; GO:0060348; GO:0097011; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0001503; GO:0017046; GO:0005886; GO:0004672; GO:0007168,ATP binding; GTP binding; bone development; cellular response to granulocyte macrophage colony-stimulating factor stimulus; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; ossification; peptide hormone binding; plasma membrane; protein kinase activity; receptor guanylyl cyclase signaling pathway,PF01094;PF00211;PF07714;,,,,,,,,,ANPRB_RAT,Rattus norvegicus (Rat),bone development [GO:0060348]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]; single organism reproductive process [GO:0044702] comp151515_c0_seq1,201,42.7861,0.561125,2,6,,1.00E-22,Q8T498,Probable Ras GTPase-activating protein,Probable Ras GTPase-activating protein,GO:0005096; GO:0005737; GO:0007476; GO:0002121; GO:0046580; GO:0005543; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; negative regulation of Ras protein signal transduction; phospholipid binding; positive regulation of GTPase activity; signal transduction,PF00168;PF12004;PF00616;,6.00E-17,CHOYP_NGAP.2.2,,,,,,,GAP2_DROME,Drosophila melanogaster (Fruit fly),imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165] comp151527_c0_seq1,271,43.9114,0.61574126,8,0,,1.00E-19,Q9JI18,Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT),GO:0005509; GO:0016021; GO:0050750; GO:0005041; GO:0016020,calcium ion binding; integral to membrane; low-density lipoprotein particle receptor binding; low-density lipoprotein receptor activity; membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1B_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701] comp151534_c0_seq1,316,37.9747,0.53790131,1,12,,1.00E-10,Q6NTV6,Inverted formin-2,Inverted formin-2,GO:0030036,actin cytoskeleton organization,PF06367;PF06371;PF02181;,,,,,,,,,INF2_XENLA,Xenopus laevis (African clawed frog),actin cytoskeleton organization [GO:0030036] comp151544_c0_seq1,217,42.3963,0.30908029,1,13,,6.00E-12,Q5R6C7,RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3),RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3),GO:0003723; GO:0000166; GO:0005634,RNA binding; nucleotide binding; nucleus,PF00076;,,,,,,,,,RBM40_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp151559_c0_seq1,240,40.8333,0.40150635,7,0,,1.00E-11,Q8JHZ8,Paladin,Paladin,GO:0005829,cytosol,,9.00E-16,CHOYP_LOC100563071.1.1,,,,,,,PALD_CHICK,Gallus gallus (Chicken), comp151562_c0_seq1,206,48.0583,0.44651613,0,10,,1.00E-18,O02791,Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase),Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase),GO:0005975; GO:0004336; GO:0006683; GO:0005764; GO:0005739,carbohydrate metabolic process; galactosylceramidase activity; galactosylceramide catabolic process; lysosome; mitochondrion,PF02057;,4.00E-25,CHOYP_LOC100376265.3.4,,,,,,,GALC_MACMU,Macaca mulatta (Rhesus macaque),carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683] comp151566_c0_seq1,379,42.2164,0.38000265,9,6,,1.00E-38,Q9Z139,"Tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1)","Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1)",GO:0005524; GO:0005887; GO:0004714; GO:0007169,ATP binding; integral to plasma membrane; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF01392;PF07679;PF00051;PF07714;,9.00E-50,CHOYP_LOC100533220.2.2,,,,,,,ROR1_MOUSE,Mus musculus (Mouse),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055] comp151586_c0_seq1,386,48.7047,0.41287617,13,5,,8.00E-43,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,4.00E-67,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp151589_c0_seq1,262,43.8931,0.50969735,5,5,,7.00E-33,O15442,Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-) (Adult brain protein 239) (239AB),Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-) (Adult brain protein 239) (239AB),GO:0016787,hydrolase activity,PF00149;,1.00E-14,CHOYP_LOC100636083.1.1,,,,,,,MPPD1_HUMAN,Homo sapiens (Human), comp151591_c0_seq1,314,37.2611,0.37612322,12,2,,6.00E-12,F1MH24,AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1),AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1),GO:0035612; GO:0005524; GO:0005112; GO:0031252; GO:0030136; GO:0005905; GO:0006897; GO:0019897; GO:0045747; GO:0046777; GO:0004674; GO:0050821; GO:2000369; GO:0032880; GO:0043195,AP-2 adaptor complex binding; ATP binding; Notch binding; cell leading edge; clathrin-coated vesicle; coated pit; endocytosis; extrinsic to plasma membrane; positive regulation of Notch signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein stabilization; regulation of clathrin-mediated endocytosis; regulation of protein localization; terminal bouton,PF00069;,,,,,,,,,AAK1_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of protein localization [GO:0032880] comp151615_c0_seq1,211,46.4455,0.48073642,4,6,,2.00E-16,P91621,"Protein still life, isoform SIF type 1","Protein still life, isoform SIF type 1",GO:0030676; GO:0030054; GO:0035556; GO:0005543; GO:0051491; GO:0005057; GO:0032314; GO:0050770; GO:0050803; GO:0045202,Rac guanyl-nucleotide exchange factor activity; cell junction; intracellular signal transduction; phospholipid binding; positive regulation of filopodium assembly; receptor signaling protein activity; regulation of Rac GTPase activity; regulation of axonogenesis; regulation of synapse structure and activity; synapse,PF00169;PF02196;PF00621;,7.00E-23,CHOYP_AGAP_AGAP006590.1.1,,,,,,,SIF1_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; positive regulation of filopodium assembly [GO:0051491]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synapse structure or activity [GO:0050803] comp151628_c0_seq1,203,44.335,0.40618208,5,7,,1.00E-14,Q6P2P2,Putative protein arginine N-methyltransferase 10 (EC 2.1.1.-),Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-),GO:0005737; GO:0008276,cytoplasm; protein methyltransferase activity,,,,,,,,,,ANM10_HUMAN,Homo sapiens (Human),protein methylation [GO:0006479] comp151629_c0_seq1,249,38.5542,0.43573688,1,12,,5.00E-13,P17030,Zinc finger protein 25 (Zinc finger protein KOX19),Zinc finger protein 25 (Zinc finger protein KOX19),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF25_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp151635_c0_seq1,286,33.5664,0.24913499,15,0,,2.00E-12,O75140,DEP domain-containing protein 5,DEP domain-containing protein 5,GO:0005096; GO:0005829; GO:0035556; GO:0005765; GO:0048471; GO:0043547,GTPase activator activity; cytosol; intracellular signal transduction; lysosomal membrane; perinuclear region of cytoplasm; positive regulation of GTPase activity,PF00610;PF12257;,,,,,,,,,DEPD5_HUMAN,Homo sapiens (Human),cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007] comp151660_c0_seq1,268,42.1642,0.33709743,6,6,,7.00E-43,O61735,Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1),Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1),GO:0003677; GO:0048148; GO:0032922; GO:0005737; GO:0008062; GO:0045475; GO:0000122; GO:0005634; GO:0045944; GO:0046982; GO:0045187; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"DNA binding; behavioral response to cocaine; circadian regulation of gene expression; cytoplasm; eclosion rhythm; locomotor rhythm; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; regulation of circadian sleep/wake cycle, sleep; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;,5.00E-45,CHOYP_LOC100552330.1.1,,,,,,,CLOCK_DROME,Drosophila melanogaster (Fruit fly),"behavioral response to cocaine [GO:0048148]; circadian regulation of gene expression [GO:0032922]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; eclosion rhythm [GO:0008062]; entrainment of circadian clock [GO:0009649]; locomotor rhythm [GO:0045475]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to temperature stimulus [GO:0009266]; rhythmic behavior [GO:0007622]; transcription, DNA-templated [GO:0006351]" comp151680_c0_seq1,333,40.2402,0.83028997,7,13,,1.00E-18,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,4.00E-22,CHOYP_HSPA12A.20.27,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp151681_c0_seq1,510,43.9216,0.32967869,27,0,,2.00E-06,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp151684_c0_seq1,292,43.4932,0.51585112,10,4,,5.00E-28,Q80XK6,Autophagy-related protein 2 homolog B,Autophagy-related protein 2 homolog B,GO:0006914; GO:0005811; GO:0034045,autophagy; lipid particle; pre-autophagosomal structure membrane,PF13329;PF09333;PF12624;,1.00E-20,CHOYP_ATG2A.1.1,,,,,,,ATG2B_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp151687_c0_seq1,213,38.0282,0.6548492,2,8,,6.00E-09,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp151692_c0_seq1,224,44.6429,0.45290758,4,6,,2.00E-17,Q41254,Rac-like GTP-binding protein RAC9,Rac-like GTP-binding protein RAC9,GO:0005525; GO:0005737; GO:0016020; GO:0007264,GTP binding; cytoplasm; membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAC9_GOSHI,Gossypium hirsutum (Upland cotton) (Gossypium mexicanum),small GTPase mediated signal transduction [GO:0007264] comp151702_c0_seq1,229,37.9913,0.36586064,0,12,,4.00E-17,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp151703_c0_seq1,300,41.6667,0.23454806,10,0,,6.00E-15,Q149M9,NACHT and WD repeat domain-containing protein 1,NACHT domain- and WD repeat-containing protein 1,GO:0005524,ATP binding,PF12894;PF00400;,2.00E-24,CHOYP_LOC100366460.2.2,,,,,,,NWD1_HUMAN,Homo sapiens (Human), comp151717_c0_seq1,203,57.6355,1.319256,0,12,,2.00E-08,Q63P06,Ribose import ATP-binding protein RbsA (EC 3.6.3.17),Ribose import ATP-binding protein RbsA (EC 3.6.3.17),GO:0005524; GO:0006200; GO:0015407; GO:0005886,ATP binding; ATP catabolic process; monosaccharide-transporting ATPase activity; plasma membrane,PF00005;,,,,,,,,,RBSA_BURPS,Burkholderia pseudomallei (strain K96243), comp151720_c0_seq1,408,38.7255,0.85208845,12,0,,7.00E-10,O75626,PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1),GO:0045165; GO:0005737; GO:0001892; GO:0042462; GO:0007281; GO:0001893; GO:0046872; GO:0008168; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0043565; GO:0003700; GO:0006351,"cell fate commitment; cytoplasm; embryonic placenta development; eye photoreceptor cell development; germ cell development; maternal placenta development; metal ion binding; methyltransferase activity; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00856;PF13912;,,,,,,,,,PRDM1_HUMAN,Homo sapiens (Human),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp151738_c0_seq1,358,47.486,0.2027978,12,0,,5.00E-10,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,2.00E-31,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp151741_c0_seq1,297,38.3838,0.65495248,6,6,,2.00E-06,Q95LL3,TBC1 domain family member 22B,TBC1 domain family member 22B,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,,,,,,,,,TB22B_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp151747_c0_seq1,322,45.9627,0.531741,2,14,,3.00E-29,Q5RA75,Protein FAM135A,Protein FAM135A,,,PF12394;PF05057;,,,,,,,,,F135A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp151755_c0_seq1,215,38.1395,0.38919761,3,10,,1.00E-06,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp151759_c0_seq1,223,46.1883,0.94408029,2,11,,,,,,,,,6.00E-11,CHOYP_TVAG_355490.10.22,,,,,,,,, comp151770_c0_seq1,346,47.1098,0.43361812,16,0,,2.00E-35,B1AVY7,Kinesin-like protein KIF16B,Kinesin-like protein KIF16B,GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,8.00E-44,CHOYP_KI16B.1.3,,,,,,,KI16B_MOUSE,Mus musculus (Mouse),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp151771_c0_seq1,348,44.8276,0.63141969,11,5,,2.00E-25,Q9P2H5,Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35),Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP35_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp151772_c0_seq1,246,43.4959,0.69092051,5,4,,9.00E-07,Q8CAS9,Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog),Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog),GO:0003950; GO:0005737; GO:0005829; GO:0006302; GO:0005634; GO:0060330,NAD+ ADP-ribosyltransferase activity; cytoplasm; cytosol; double-strand break repair; nucleus; regulation of response to interferon-gamma,PF01661;,,,,,,,,,PARP9_MOUSE,Mus musculus (Mouse),double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330] comp151773_c0_seq1,304,41.4474,0.38510518,8,1,,,,,,,,,7.00E-12,CHOYP_GEMIN5.2.2,,,,,,,,, comp151776_c0_seq1,274,40.8759,0.43846247,9,5,,6.00E-14,Q9D328,Transmembrane protein 35 (Peroxisomal membrane protein 52) (PMP52),Transmembrane protein 35 (Peroxisomal membrane protein 52) (PMP52),GO:0016023; GO:0016021; GO:0005778,cytoplasmic membrane-bounded vesicle; integral to membrane; peroxisomal membrane,PF13564;,2.00E-17,CHOYP_AGAP_AGAP007501.1.1,,,,,,,TMM35_MOUSE,Mus musculus (Mouse), comp151777_c0_seq1,250,41.2,0.88174713,7,6,,3.00E-07,Q9WWW2,Alcohol dehydrogenase [acceptor] (EC 1.1.99.-),Alcohol dehydrogenase [acceptor] (EC 1.1.99.-),GO:0006066; GO:0008812; GO:0050660; GO:0005886,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding; plasma membrane,PF05199;PF00732;,,,,,,,,,ALKJ_PSEPU,Pseudomonas putida (Arthrobacter siderocapsulatus), comp151784_c0_seq1,345,41.4493,0.27137483,9,0,,1.00E-23,Q8R2R5,Leucine-rich repeat-containing protein 61,Leucine-rich repeat-containing protein 61,,,,,,,,,,,,LRC61_MOUSE,Mus musculus (Mouse), comp151796_c0_seq1,379,62.2691,1.24093752,0,17,,2.00E-09,O86350,NADH-quinone oxidoreductase subunit L (EC 1.6.99.5) (NADH dehydrogenase I subunit L) (NDH-1 subunit L),,GO:0042773; GO:0008137; GO:0016021; GO:0005886; GO:0048038; GO:0052572,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; integral to membrane; plasma membrane; quinone binding; response to host immune response,,,,,,,,,,NUOL_MYCTU,, comp151799_c0_seq1,261,45.2107,0.45212053,1,9,,6.00E-15,Q9JKJ9,24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.13.99) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase),24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase),GO:0033782; GO:0006699; GO:0030573; GO:0006707; GO:0007586; GO:0005789; GO:0020037; GO:0043231; GO:0005506; GO:0008396; GO:0008387,24-hydroxycholesterol 7alpha-hydroxylase activity; bile acid biosynthetic process; bile acid catabolic process; cholesterol catabolic process; digestion; endoplasmic reticulum membrane; heme binding; intracellular membrane-bounded organelle; iron ion binding; oxysterol 7-alpha-hydroxylase activity; steroid 7-alpha-hydroxylase activity,PF00067;,,,,,,,,,CP39A_MOUSE,Mus musculus (Mouse),bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586] comp15180_c0_seq1,265,34.3396,0.9127581,6,0,,1.00E-10,Q80SU7,Interferon-induced very large GTPase 1 (Very large-inducible GTPase-1) (VLIG-1),Interferon-induced very large GTPase 1 (Very large-inducible GTPase-1) (VLIG-1),GO:0005525; GO:0005829; GO:0005634,GTP binding; cytosol; nucleus,,,,,,,,,,GVIN1_MOUSE,Mus musculus (Mouse), comp151812_c0_seq1,247,44.9393,0.25050916,1,13,,1.00E-20,P48067,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),GO:0015375; GO:0005887; GO:0005328,glycine:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,SC6A9_HUMAN,Homo sapiens (Human),"glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp151825_c0_seq1,205,49.7561,0.85656924,1,7,,3.00E-11,P16546,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)",GO:0030018; GO:0051693; GO:0005509; GO:0032437; GO:0005916; GO:0016328; GO:0033270; GO:0046982; GO:0030507,Z disc; actin filament capping; calcium ion binding; cuticular plate; fascia adherens; lateral plasma membrane; paranode region of axon; protein heterodimerization activity; spectrin binding,PF13499;PF08726;PF00018;PF00435;,,,,,,,,,SPTN1_MOUSE,Mus musculus (Mouse),actin filament capping [GO:0051693] comp151856_c0_seq1,203,37.4384,0.56865491,2,6,,,,,,,,,1.00E-13,CHOYP_LOC584740.1.2,,,,,,,,, comp151859_c0_seq1,217,58.5253,0.87728221,0,13,,4.00E-06,Q8YJ22,Leu/Ile/Val-binding protein homolog 2,Leu/Ile/Val-binding protein homolog 2,GO:0006865; GO:0030288,amino acid transport; outer membrane-bounded periplasmic space,PF13458;,,,,,,,,,LIVB2_BRUME,Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094),amino acid transport [GO:0006865] comp151868_c0_seq1,242,47.1074,0.83194698,0,11,,4.00E-11,Q99L04,Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),GO:0005783; GO:0005743; GO:0016491,endoplasmic reticulum; mitochondrial inner membrane; oxidoreductase activity,PF00106;,,,,,,,,,DHRS1_MOUSE,Mus musculus (Mouse), comp151869_c0_seq1,214,46.2617,0.81372677,7,0,,4.00E-14,Q8VIH3,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (rCNT3),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (rCNT3),GO:0016021; GO:0001882; GO:0005415; GO:0001895,integral to membrane; nucleoside binding; nucleoside:sodium symporter activity; retina homeostasis,PF07670;PF07662;PF01773;,9.00E-15,CHOYP_NEMVEDRAFT_V1G135437.1.2,,,,,,,S28A3_RAT,Rattus norvegicus (Rat),pyrimidine nucleoside transport [GO:0015864]; retina homeostasis [GO:0001895] comp151870_c0_seq1,238,45.7983,0.73164557,10,5,,9.00E-33,Q5HZQ9,Pecanex-like protein 4,Pecanex-like protein 4 (Pecanex homolog protein 4),GO:0016021,integral to membrane,PF05041;,1.00E-25,CHOYP_LOC100376367.1.1,,,,,,,PCX4_XENLA,Xenopus laevis (African clawed frog), comp151891_c0_seq1,362,41.7127,0.51950307,10,5,,1.00E-42,Q9W391,Probable phosphorylase b kinase regulatory subunit alpha (Phosphorylase kinase subunit alpha),Probable phosphorylase b kinase regulatory subunit alpha (Phosphorylase kinase subunit alpha),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,7.00E-45,CHOYP_LOC100368228.3.3,,,,,,,KPBA_DROME,Drosophila melanogaster (Fruit fly),glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp151904_c0_seq1,401,49.1272,0.67379426,10,2,,7.00E-47,Q8BVQ5,Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89),Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89),GO:0004091; GO:0051722; GO:0006482; GO:0051721,carboxylesterase activity; protein C-terminal methylesterase activity; protein demethylation; protein phosphatase 2A binding,PF12697;,7.00E-26,CHOYP_PPME1.1.1,,,,,,,PPME1_MOUSE,Mus musculus (Mouse),protein demethylation [GO:0006482] comp151906_c0_seq1,304,40.1316,1.14878833,5,6,,4.00E-23,Q8BMQ3,Zinc finger protein basonuclin-2,Zinc finger protein basonuclin-2,GO:0003677; GO:0005737; GO:0003416; GO:0060485; GO:0046872; GO:0005634; GO:0060021; GO:0005886; GO:0006355; GO:0043586; GO:0006351,"DNA binding; cytoplasm; endochondral bone growth; mesenchyme development; metal ion binding; nucleus; palate development; plasma membrane; regulation of transcription, DNA-dependent; tongue development; transcription, DNA-dependent",,,,,,,,,,BNC2_MOUSE,Mus musculus (Mouse),"endochondral bone growth [GO:0003416]; mesenchyme development [GO:0060485]; palate development [GO:0060021]; regulation of transcription, DNA-templated [GO:0006355]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]" comp151914_c0_seq1,259,45.5598,0.74692294,5,5,,,,,,,,,4.00E-14,CHOYP_TRIADDRAFT_51756.1.1,,,,,,,,, comp151924_c0_seq1,222,35.1351,0.44452729,2,8,,1.00E-23,O96017,Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2),Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2),GO:0005524; GO:0006975; GO:0000086; GO:0016605; GO:0051301; GO:0044257; GO:0006302; GO:0008630; GO:0046872; GO:0045893; GO:0046777; GO:0042803; GO:0004674; GO:0050821; GO:0042176; GO:0090399; GO:0010332; GO:0072428; GO:0090307; GO:0006351,"ATP binding; DNA damage induced protein phosphorylation; G2/M transition of mitotic cell cycle; PML body; cell division; cellular protein catabolic process; double-strand break repair; intrinsic apoptotic signaling pathway in response to DNA damage; metal ion binding; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; protein stabilization; regulation of protein catabolic process; replicative senescence; response to gamma radiation; signal transduction involved in intra-S DNA damage checkpoint; spindle assembly involved in mitosis; transcription, DNA-dependent",PF00498;PF00069;,,,,,,,,,CHK2_HUMAN,Homo sapiens (Human),"cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to doxorubicin [GO:1902520]; response to gamma radiation [GO:0010332]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]; transcription, DNA-templated [GO:0006351]" comp151926_c0_seq1,452,42.2566,0.39737037,8,13,,1.00E-42,Q6P6Y1,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,,,,2.00E-34,CHOYP_K1468.1.1,,,,,,,K1468_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp151932_c0_seq1,201,47.7612,0.96611087,2,6,,,,,,,,,7.00E-16,CHOYP_LOC100560153.3.3,,,,,,,,, comp151934_c0_seq1,240,61.6667,0.96841864,0,15,,2.00E-24,Q9RJ47,Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A),Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A),GO:0051539; GO:0005525; GO:0006777; GO:0016829; GO:0046872; GO:0019008,"4 iron, 4 sulfur cluster binding; GTP binding; Mo-molybdopterin cofactor biosynthetic process; lyase activity; metal ion binding; molybdopterin synthase complex",PF06463;PF04055;,,,,,,,,,MOAA_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp151937_c0_seq1,437,40.7323,0.66768642,14,0,,2.00E-06,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp151950_c0_seq1,210,60.9524,1.1377709,0,13,,4.00E-38,Q6A830,Lipoprotein LpqB,Lipoprotein LpqB,GO:0005886,plasma membrane,PF10646;PF10647;,,,,,,,,,LPQB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp151964_c0_seq1,202,40.099,0.61967331,8,0,,3.00E-06,Q05941,Neuronal acetylcholine receptor subunit alpha-7,Neuronal acetylcholine receptor subunit alpha-7,GO:0051117; GO:0042113; GO:0042110; GO:0042166; GO:0004889; GO:0005892; GO:0016324; GO:0008306; GO:0032279; GO:0030424; GO:0048149; GO:0035095; GO:0006816; GO:0030054; GO:0005737; GO:0043198; GO:0043197; GO:0042416; GO:0008144; GO:0006897; GO:0009897; GO:0060112; GO:0030426; GO:0045121; GO:0007613; GO:0050728; GO:0032691; GO:0032715; GO:0032720; GO:0043025; GO:0001988; GO:0014069; GO:0045211; GO:0042734; GO:0019228; GO:0014061; GO:0032225; GO:0032094; GO:0097110; GO:0030317; GO:0007271,"ATPase binding; B cell activation; T cell activation; acetylcholine binding; acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; apical plasma membrane; associative learning; asymmetric synapse; axon; behavioral response to ethanol; behavioral response to nicotine; calcium ion transport; cell junction; cytoplasm; dendritic shaft; dendritic spine; dopamine biosynthetic process; drug binding; endocytosis; external side of plasma membrane; generation of ovulation cycle rhythm; growth cone; membrane raft; memory; negative regulation of inflammatory response; negative regulation of interleukin-1 beta production; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; neuronal cell body; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure; postsynaptic density; postsynaptic membrane; presynaptic membrane; regulation of action potential in neuron; regulation of norepinephrine secretion; regulation of synaptic transmission, dopaminergic; response to food; scaffold protein binding; sperm motility; synaptic transmission, cholinergic",PF02931;PF02932;,,,,,,,,,ACHA7_RAT,Rattus norvegicus (Rat),"calcium ion transport [GO:0006816]; dopamine biosynthetic process [GO:0042416]; neuronal action potential [GO:0019228]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" comp151967_c0_seq1,294,45.2381,1.13926806,1,9,,7.00E-07,Q47944,L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32),L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32),GO:0006066; GO:0008812; GO:0050660,alcohol metabolic process; choline dehydrogenase activity; flavin adenine dinucleotide binding,PF05199;PF00732;,,,,,,,,,SDH_GLUOY,Gluconobacter oxydans (Gluconobacter suboxydans), comp151992_c0_seq1,358,45.8101,0.75026709,4,8,,2.00E-09,Q9C0A1,Zinc finger homeobox protein 2 (Zinc finger homeodomain protein 2) (ZFH-2),Zinc finger homeobox protein 2 (Zinc finger homeodomain protein 2) (ZFH-2),GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;,,,,,,,,,ZFHX2_HUMAN,Homo sapiens (Human),"adult behavior [GO:0030534]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp151994_c0_seq1,278,33.8129,0.51358235,2,11,,4.00E-09,P18732,Gastrula zinc finger protein XlCGF64.1 (Fragment),Gastrula zinc finger protein XlCGF64.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG64_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp151998_c0_seq1,277,44.4043,0.73507039,7,8,,4.00E-06,Q0ZLH2,Pejvakin (Autosomal recessive deafness type 59 protein homolog),Pejvakin (Autosomal recessive deafness type 59 protein homolog),GO:0043025; GO:0007605,neuronal cell body; sensory perception of sound,PF04598;,,,,,,,,,PJVK_MOUSE,Mus musculus (Mouse),sensory perception of sound [GO:0007605] comp152019_c0_seq1,296,44.2568,0.35206661,2,10,,1.00E-37,P47740,Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A2),Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A2),GO:0004029; GO:0004030; GO:0006081; GO:0005783; GO:0005789; GO:0016021; GO:0005743,aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; cellular aldehyde metabolic process; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; mitochondrial inner membrane,PF00171;,,,,,,,,,AL3A2_MOUSE,Mus musculus (Mouse),cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; formaldehyde metabolic process [GO:0046292]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; response to reactive oxygen species [GO:0000302]; sesquiterpenoid metabolic process [GO:0006714] comp152034_c0_seq1,214,45.3271,0.3723025,3,9,,4.00E-08,P11442,Clathrin heavy chain 1,Clathrin heavy chain 1,GO:0007030; GO:0030315; GO:0030506; GO:0030118; GO:0030132; GO:0030130; GO:0030669; GO:0031072; GO:0006886; GO:0042470; GO:0007067; GO:0042277; GO:0006898; GO:0005819; GO:0005198,Golgi organization; T-tubule; ankyrin binding; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin-coated endocytic vesicle membrane; heat shock protein binding; intracellular protein transport; melanosome; mitosis; peptide binding; receptor-mediated endocytosis; spindle; structural molecule activity,PF00637;PF09268;PF01394;,,,,,,,,,CLH_RAT,Rattus norvegicus (Rat),Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic nuclear division [GO:0007067]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; receptor-mediated endocytosis [GO:0006898] comp152038_c0_seq1,210,43.3333,0.64593301,10,0,,8.00E-24,P48768,Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0033280; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; plasma membrane; response to vitamin D; telencephalon development,PF03160;PF01699;PF16494;,2.00E-30,CHOYP_LOC100371845.1.3,,,,,,,NAC2_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp152049_c0_seq1,249,45.7831,1.0006319,1,6,,7.00E-08,P23342,Monomeric sarcosine oxidase (MSOX) (EC 1.5.3.1),Monomeric sarcosine oxidase (MSOX) (EC 1.5.3.1),GO:0005737; GO:0008115; GO:0046653,cytoplasm; sarcosine oxidase activity; tetrahydrofolate metabolic process,PF01266;,,,,,,,,,MSOX_BACSN,Bacillus sp. (strain NS-129),tetrahydrofolate metabolic process [GO:0046653] comp152055_c0_seq1,233,36.9099,0.63588128,2,8,,2.00E-06,A2VCV0,Opioid growth factor receptor-like protein 1,Opioid growth factor receptor-like protein 1,GO:0016020; GO:0004872,membrane; receptor activity,PF04664;,,,,,,,,,OGRL1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp152072_c0_seq1,384,48.4375,0.40067339,5,10,,2.00E-09,Q8IVV2,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp152076_c0_seq1,346,42.4855,0.45727039,5,11,,5.00E-57,A8WH18,Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein),Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein),GO:0051539; GO:0097361; GO:0016226; GO:0046872,"4 iron, 4 sulfur cluster binding; CIA complex; iron-sulfur cluster assembly; metal ion binding",PF02906;PF02256;,3.00E-48,CHOYP_BRAFLDRAFT_118961.1.1,,,,,,,NARFL_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),iron-sulfur cluster assembly [GO:0016226] comp152084_c0_seq1,327,45.5657,0.4138467,1,13,,1.00E-21,Q66J99,Probable RNA-binding protein 18 (RNA-binding motif protein 18),Probable RNA-binding protein 18 (RNA-binding motif protein 18),GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,,,,,,,,,RBM18_XENLA,Xenopus laevis (African clawed frog), comp152088_c0_seq1,253,37.5494,0.56295206,4,8,,,,,,,,,,,6.00E-16,ruditapes_c27756,,,,,,, comp152090_c0_seq1,233,40.3433,0.42372895,1,8,,5.00E-15,Q5R991,Late secretory pathway protein AVL9 homolog,Late secretory pathway protein AVL9 homolog,GO:0016477; GO:0016021; GO:0055037,cell migration; integral to membrane; recycling endosome,PF09794;,,,,,,,,,AVL9_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell migration [GO:0016477] comp152103_c0_seq1,221,39.819,0.12231655,0,12,,7.00E-21,Q92611,ER degradation-enhancing alpha-mannosidase-like protein 1,ER degradation-enhancing alpha-mannosidase-like protein 1,GO:0030433; GO:0006987; GO:0005509; GO:0030176; GO:0051787; GO:0043687; GO:0018279; GO:0006457,ER-associated protein catabolic process; activation of signaling protein activity involved in unfolded protein response; calcium ion binding; integral to endoplasmic reticulum membrane; misfolded protein binding; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding,PF01532;,,,,,,,,,EDEM1_HUMAN,Homo sapiens (Human),"endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; IRE1-mediated unfolded protein response [GO:0036498]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on C branch [GO:0036510]" comp152109_c0_seq1,213,61.9718,1.03383921,0,9,,2.00E-28,P26829,NADH dehydrogenase (EC 1.6.99.3) (Alkyl hydroperoxide reductase),NADH dehydrogenase (EC 1.6.99.3) (Alkyl hydroperoxide reductase),GO:0051287; GO:0003954; GO:0008785; GO:0045454; GO:0009055; GO:0050660; GO:0005886; GO:0015035; GO:0000302,NAD binding; NADH dehydrogenase activity; alkyl hydroperoxide reductase activity; cell redox homeostasis; electron carrier activity; flavin adenine dinucleotide binding; plasma membrane; protein disulfide oxidoreductase activity; response to reactive oxygen species,PF07992;PF13192;,,,,,,,,,DHNA_BACYN,Bacillus sp. (strain YN-1),cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302] comp152110_c0_seq1,245,46.5306,0.95845753,3,6,,7.00E-16,B3SV56,Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1),Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,2.00E-24,CHOYP_SMP_034860.1.1,,,,,,,NR1D1_SHEEP,Ovis aries (Sheep),"cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; circadian temperature homeostasis [GO:0060086]; glycogen biosynthetic process [GO:0005978]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasomal protein catabolic process [GO:0010498]; regulation of cholesterol homeostasis [GO:2000188]; regulation of circadian rhythm [GO:0042752]; regulation of fat cell differentiation [GO:0045598]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to leptin [GO:0044321]; transcription, DNA-templated [GO:0006351]" comp152113_c0_seq1,238,46.6387,0.70112059,3,4,,2.00E-19,Q4V8U5,Anoctamin-10 (Transmembrane protein 16K),Anoctamin-10 (Transmembrane protein 16K),GO:0016021,integral to membrane,PF04547;,2.00E-29,CHOYP_BRAFLDRAFT_75374.1.1,,,,,,,ANO10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp152129_c0_seq1,210,60.4762,0.93170944,0,9,,9.00E-20,P65336,4-alpha-glucanotransferase (EC 2.4.1.25) (Amylomaltase) (Disproportionating enzyme) (D-enzyme),,GO:0004134; GO:0005829,4-alpha-glucanotransferase activity; cytosol,,,,,,,,,,MALQ_MYCTU,, comp152148_c0_seq1,469,43.0704,0.44918968,16,0,,1.00E-49,Q9UPW8,Protein unc-13 homolog A (Munc13-1),Protein unc-13 homolog A (Munc13-1),GO:0050435; GO:0030054; GO:0005737; GO:0019992; GO:0060384; GO:0035556; GO:0046872; GO:0031594; GO:0007528; GO:0001956; GO:0042734; GO:0048172; GO:0035249; GO:0016081; GO:0016188; GO:0016082,"beta-amyloid metabolic process; cell junction; cytoplasm; diacylglycerol binding; innervation; intracellular signal transduction; metal ion binding; neuromuscular junction; neuromuscular junction development; positive regulation of neurotransmitter secretion; presynaptic membrane; regulation of short-term neuronal synaptic plasticity; synaptic transmission, glutamatergic; synaptic vesicle docking involved in exocytosis; synaptic vesicle maturation; synaptic vesicle priming",PF00130;PF00168;PF06292;PF10540;,3.00E-50,CHOYP_LOC100650524.2.2,,,,,,,UN13A_HUMAN,Homo sapiens (Human),"beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]" comp152154_c0_seq1,250,63.6,1.03588959,0,12,,7.00E-43,B2UEG8,Deoxyguanosinetriphosphate triphosphohydrolase-like protein,Deoxyguanosinetriphosphate triphosphohydrolase-like protein,GO:0046039; GO:0008832; GO:0000287; GO:0008081,GTP metabolic process; dGTPase activity; magnesium ion binding; phosphoric diester hydrolase activity,PF01966;PF13286;,,,,,,,,,DGTL1_RALPJ,Ralstonia pickettii (strain 12J),GTP metabolic process [GO:0046039] comp152156_c0_seq1,245,47.3469,0.52758232,7,0,,6.00E-33,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-54,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp152176_c0_seq1,416,42.0673,1.08963264,14,1,,,,,,,,,,,2.00E-13,ruditapes2_c2711,,,,,,, comp152182_c0_seq1,344,45.0581,0.6958042,12,0,,3.00E-13,Q8YRI1,Uncharacterized WD repeat-containing protein alr3466,Uncharacterized WD repeat-containing protein alr3466,GO:0006355,"regulation of transcription, DNA-dependent",PF00805;PF00400;,,,,,,,,,YY46_NOSS1,Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576), comp152190_c0_seq1,340,39.1176,0.46712733,4,10,,8.00E-10,Q9UPU7,TBC1 domain family member 2B,TBC1 domain family member 2B,GO:0005097; GO:0005543; GO:0032851,Rab GTPase activator activity; phospholipid binding; positive regulation of Rab GTPase activity,PF00169;PF00566;,,,,,,,,,TBD2B_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp152194_c0_seq1,202,51.9802,1.03573967,2,7,,7.00E-20,Q2PG55,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,3.00E-14,CHOYP_LOC100368611.1.1,,,,,,,S6A13_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp152205_c0_seq1,245,48.5714,0.50204918,9,0,,4.00E-19,A8MXQ7,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,,,,,,,,,,,,YH010_HUMAN,Homo sapiens (Human), comp152208_c0_seq1,273,49.0842,0.42765345,4,5,,1.00E-40,Q5RF15,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF12796;PF07714;,3.00E-41,CHOYP_LOC576866.1.1,,,,,,,TNI3K_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp152228_c0_seq1,271,43.1734,0.56332128,6,4,,6.00E-25,Q6NZK8,Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-),GO:0005929; GO:0060271; GO:0035335; GO:0004725; GO:0008138,cilium; cilium morphogenesis; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity,PF00782;,1.00E-14,CHOYP_LOC100890521.1.1,,,,,,,PTPC1_MOUSE,Mus musculus (Mouse),cilium morphogenesis [GO:0060271]; smoothened signaling pathway [GO:0007224] comp152239_c0_seq1,316,45.5696,0.55301969,10,0,,1.00E-27,A2V7M9,Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1),Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1),GO:0006506; GO:0006505; GO:0000139; GO:0016788; GO:0016021; GO:0031227,"GPI anchor biosynthetic process; GPI anchor metabolic process; Golgi membrane; hydrolase activity, acting on ester bonds; integral to membrane; intrinsic to endoplasmic reticulum membrane",PF04080;,1.00E-28,CHOYP_LOC663374.1.1,,,,,,,PGAP3_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505] comp152245_c0_seq1,251,49.4024,0.92164472,2,10,,9.00E-09,Q652N5,"Probable anion transporter 4, chloroplastic (Phosphate transporter 4;4)","Probable anion transporter 4, chloroplastic (Phosphate transporter 4;4)",GO:0031969; GO:0016021; GO:0006811; GO:0055085,chloroplast membrane; integral to membrane; ion transport; transmembrane transport,PF07690;,,,,,,,,,PHT44_ORYSJ,Oryza sativa subsp. japonica (Rice),anion transmembrane transport [GO:0098656] comp152252_c0_seq1,292,45.5479,0.57451654,4,10,,1.00E-09,Q6QNK2,Probable G-protein coupled receptor 133 (G-protein coupled receptor PGR25),Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25),GO:0004930; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF01825;,,,,,,,,,GP133_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579] comp152282_c0_seq1,329,46.2006,0.70626656,1,14,,1.00E-19,Q1KLR6,Beta-secretase 1 (EC 3.4.23.46) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2),Beta-secretase 1 (EC 3.4.23.46) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2),GO:0005794; GO:0004190; GO:0030424; GO:0050435; GO:0009986; GO:0030659; GO:0005783; GO:0005768; GO:0005887; GO:0006508; GO:0005802,Golgi apparatus; aspartic-type endopeptidase activity; axon; beta-amyloid metabolic process; cell surface; cytoplasmic vesicle membrane; endoplasmic reticulum; endosome; integral to plasma membrane; proteolysis; trans-Golgi network,PF00026;,,,,,,,,,BACE1_CAVPO,Cavia porcellus (Guinea pig),beta-amyloid metabolic process [GO:0050435]; proteolysis [GO:0006508] comp152293_c0_seq1,230,45.6522,0,7,4,,3.00E-14,A0FKG7,Calpain-7 (EC 3.4.22.-),Calpain-7 (EC 3.4.22.-),GO:0004198; GO:0005634; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; nucleus; proteolysis,PF01067;PF04212;PF00648;,,,,,,,,,CAN7_PIG,Sus scrofa (Pig),proteolysis [GO:0006508] comp152305_c0_seq1,320,39.375,0.58394541,1,11,,2.00E-21,O76083,"High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)","High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)",GO:0047555; GO:0004114; GO:0005794; GO:0007596; GO:0005829; GO:0005783; GO:0046872; GO:0048471; GO:0032587; GO:0007165,"3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; Golgi apparatus; blood coagulation; cytosol; endoplasmic reticulum; metal ion binding; perinuclear region of cytoplasm; ruffle membrane; signal transduction",PF00233;,1.00E-46,CHOYP_BRAFLDRAFT_67316.1.1,,,,,,,PDE9A_HUMAN,Homo sapiens (Human),cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165] comp152315_c0_seq1,282,40.7801,1.28482245,7,5,,,,,,,,,2.00E-13,CHOYP_LOC100370022.1.1,5.00E-11,ruditapes_c7439,,,,,,, comp152328_c0_seq1,311,38.2637,0.45217859,8,0,,2.00E-08,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp152332_c0_seq1,210,56.6667,0.85180709,3,6,,4.00E-06,P37741,Mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GMP) (GMPP),Mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GMP) (GMPP),GO:0009298; GO:0005525; GO:0009243; GO:0004475,GDP-mannose biosynthetic process; GTP binding; O antigen biosynthetic process; mannose-1-phosphate guanylyltransferase activity,PF01050;PF00483;,,,,,,,,,MANC7_ECOLX,Escherichia coli,GDP-mannose biosynthetic process [GO:0009298]; O antigen biosynthetic process [GO:0009243] comp152338_c0_seq1,226,41.5929,0.51591919,11,0,,8.00E-06,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,1.00E-12,CHOYP_NEMVEDRAFT_V1G239043.2.6,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp152361_c0_seq1,205,52.6829,0.70743442,1,5,,1.00E-18,Q13884,Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43),Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43),GO:0030054; GO:0005737; GO:0005856; GO:0016010; GO:0006936; GO:0005543; GO:0042383; GO:0045202,cell junction; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; muscle contraction; phospholipid binding; sarcolemma; synapse,PF00595;PF00169;,2.00E-17,CHOYP_LOC592864.1.1,,,,,,,SNTB1_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936] comp152368_c0_seq1,229,58.0786,0.93666945,0,12,,2.00E-46,Q6A8Q7,"1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE)","1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE)",GO:0003844; GO:0043169; GO:0005978; GO:0004553,"1,4-alpha-glucan branching enzyme activity; cation binding; glycogen biosynthetic process; hydrolase activity, hydrolyzing O-glycosyl compounds",PF00128;PF02806;PF02922;,,,,,,,,,GLGB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glycogen biosynthetic process [GO:0005978] comp152381_c0_seq1,402,44.5274,0.85595232,12,0,,1.00E-44,Q01240,60 kDa neurofilament protein (NF60),60 kDa neurofilament protein (NF60),GO:0005882; GO:0005198,intermediate filament; structural molecule activity,PF00038;,5.00E-28,CHOYP_NF70.1.4,,,,,,,NF60_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp152394_c0_seq1,206,39.3204,0.26710307,3,3,,1.00E-21,Q9P2C4,Transmembrane protein 181,Transmembrane protein 181,GO:0016021; GO:0009405; GO:0015643,integral to membrane; pathogenesis; toxic substance binding,,8.00E-22,CHOYP_CPIPJ_CPIJ015767.1.1,,,,,,,TM181_HUMAN,Homo sapiens (Human),pathogenesis [GO:0009405] comp152395_c0_seq1,381,45.6693,0.46160361,9,9,,,,,,,,,3.00E-31,CHOYP_FAM122B.1.1,3.00E-40,ruditapes_c9902,,,,,,, comp152397_c0_seq1,301,30.2326,0.88047619,3,9,,5.00E-16,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp152400_c0_seq1,276,40.942,0.86834996,11,0,,3.00E-07,Q19319,Cadherin-4,Cadherin-4,GO:0007411; GO:0005509; GO:0007163; GO:0007156; GO:0016021; GO:0005886,axon guidance; calcium ion binding; establishment or maintenance of cell polarity; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,CADH4_CAEEL,Caenorhabditis elegans,axon guidance [GO:0007411]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuroblast migration [GO:0097402] comp152401_c0_seq1,244,38.1148,1.17226849,1,6,,2.00E-20,P31325,"Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-2)","Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-2)",GO:0005524; GO:0005516; GO:0019899; GO:0005978; GO:0005977; GO:0004689; GO:0005964,ATP binding; calmodulin binding; enzyme binding; glycogen biosynthetic process; glycogen metabolic process; phosphorylase kinase activity; phosphorylase kinase complex,PF00069;,4.00E-33,CHOYP_PHUM_PHUM607620.1.1,,,,,,,PHKG2_RAT,Rattus norvegicus (Rat),glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp152415_c0_seq1,229,54.5852,1.0615587,5,6,,4.00E-36,Q2KIR8,"L-threonine 3-dehydrogenase, mitochondrial (EC 1.1.1.103)","L-threonine 3-dehydrogenase, mitochondrial (EC 1.1.1.103)",GO:0008743; GO:0019518; GO:0050662; GO:0005739,L-threonine 3-dehydrogenase activity; L-threonine catabolic process to glycine; coenzyme binding; mitochondrion,PF01370;,4.00E-32,CHOYP_LOC101234062.1.1,,,,,,,TDH_BOVIN,Bos taurus (Bovine),L-threonine catabolic process to glycine [GO:0019518] comp152433_c0_seq1,227,58.1498,0.88977336,0,12,,4.00E-09,P48504,Cytochrome b-c1 complex subunit 6 (CR7) (Complex III subunit 6) (Complex III subunit VI) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 7.8 kDa protein),Cytochrome b-c1 complex subunit 6 (CR7) (Complex III subunit 6) (Complex III subunit VI) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 7.8 kDa protein),GO:0006122; GO:0005743; GO:0070469; GO:0008121,"mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial inner membrane; respiratory chain; ubiquinol-cytochrome-c reductase activity",PF02320;,,,,,,,,,QCR6_SOLTU,Solanum tuberosum (Potato),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp152447_c0_seq1,232,65.5172,0.96883297,0,8,,1.00E-34,A1WAW8,Elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA),Elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA),GO:0005525; GO:0006184; GO:0003924; GO:0005886; GO:0045727; GO:0043022; GO:0003746; GO:0006414,GTP binding; GTP catabolic process; GTPase activity; plasma membrane; positive regulation of translation; ribosome binding; translation elongation factor activity; translational elongation,PF00679;PF03144;PF06421;,,,,,,,,,LEPA_ACISJ,Acidovorax sp. (strain JS42),positive regulation of translation [GO:0045727] comp152454_c0_seq1,205,40.4878,0.59885146,5,4,,6.00E-08,A8XKV0,Beta carbonic anhydrase 1 (EC 4.2.1.1),Beta carbonic anhydrase 1 (EC 4.2.1.1),GO:0004089; GO:0008270,carbonate dehydratase activity; zinc ion binding,PF00484;,,,,,,,,,BCA1_CAEBR,Caenorhabditis briggsae, comp152466_c0_seq1,272,47.4265,0.39432406,9,0,,5.00E-32,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,1.00E-33,CHOYP_EMAL6.1.1,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp152473_c0_seq1,364,44.2308,0.61979474,3,4,,3.00E-43,Q9Z122,Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0004768; GO:0006636; GO:0042761,endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; stearoyl-CoA 9-desaturase activity; unsaturated fatty acid biosynthetic process; very long-chain fatty acid biosynthetic process,PF00173;PF00487;,6.00E-33,CHOYP_FADS2.1.2,,,,,,,FADS2_RAT,Rattus norvegicus (Rat),alpha-linolenic acid metabolic process [GO:0036109]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] comp152477_c0_seq1,237,40.9283,0.81022719,1,8,,2.00E-15,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,4.00E-13,CHOYP_HSPA12A.20.27,1.00E-11,ruditapes_c25622,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp152490_c0_seq1,307,44.2997,0.46788691,11,0,,1.00E-17,Q9R101,Hormone-sensitive lipase (HSL) (EC 3.1.1.79),Hormone-sensitive lipase (HSL) (EC 3.1.1.79),GO:0005901; GO:0008203; GO:0005829; GO:0033878; GO:0016298; GO:0016042; GO:0005811; GO:0005739; GO:0005634; GO:0042134; GO:0006363; GO:0006361; GO:0019433,caveola; cholesterol metabolic process; cytosol; hormone-sensitive lipase activity; lipase activity; lipid catabolic process; lipid particle; mitochondrion; nucleus; rRNA primary transcript binding; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; triglyceride catabolic process,PF07859;PF06350;,,,,,,,,,LIPS_SPETR,Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus),cholesterol metabolic process [GO:0008203]; lipid catabolic process [GO:0016042]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation from RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433] comp152509_c0_seq1,205,52.1951,0.28994356,5,4,,2.00E-09,Q5U239,Transmembrane protein 145,Transmembrane protein 145,GO:0007186; GO:0016021; GO:0019236,G-protein coupled receptor signaling pathway; integral to membrane; response to pheromone,PF10192;,,,,,,,,,TM145_XENLA,Xenopus laevis (African clawed frog),G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] comp15250_c0_seq1,210,39.0476,0.38225504,3,0,,3.00E-08,Q9EQJ0,Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1),Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1),GO:0072345; GO:0010008; GO:0016021; GO:0005765; GO:0005244,NAADP-sensitive calcium-release channel activity; endosome membrane; integral to membrane; lysosomal membrane; voltage-gated ion channel activity,PF00520;,,,,,,,,,TPC1_MOUSE,Mus musculus (Mouse),membrane depolarization during action potential [GO:0086010]; positive regulation of autophagy [GO:0010508] comp152513_c0_seq1,207,41.0628,0.9213947,8,0,,1.00E-15,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-31,CHOYP_LOC577371.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp152520_c0_seq1,319,44.5141,0.38156178,3,5,,2.00E-25,A6NJL1,Zinc finger and SCAN domain-containing protein 5B,Zinc finger and SCAN domain-containing protein 5B,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF02023;PF00096;PF13912;,,,,,,,,,ZSA5B_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp152539_c0_seq1,350,43.7143,0.60289053,12,0,,4.00E-60,Q28WQ1,Kinesin-like protein unc-104,Kinesin-like protein unc-104,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0005875; GO:0003777; GO:0005543; GO:0048489; GO:0047496,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule associated complex; microtubule motor activity; phospholipid binding; synaptic vesicle transport; vesicle transport along microtubule,PF12473;PF12423;PF00225;PF16183;PF00169;,4.00E-47,CHOYP_LOC100875479.2.2,,,,,,,KIF1A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] comp152541_c0_seq1,206,55.8252,1.06509774,0,9,,3.00E-16,Q8CK24,Arginine biosynthesis bifunctional protein ArgJ [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase (EC 2.3.1.35) (Ornithine acetyltransferase) (OATase) (Ornithine transacetylase); Amino-acid acetyltransferase (EC 2.3.1.1) (N-acetylglutamate synthase) (AGSase)],Arginine biosynthesis bifunctional protein ArgJ [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase (EC 2.3.1.35) (Ornithine acetyltransferase) (OATase) (Ornithine transacetylase); Amino-acid acetyltransferase (EC 2.3.1.1) (N-acetylglutamate synthase) (AGSase)],GO:0004042; GO:0006526; GO:0005737; GO:0004358,acetyl-CoA:L-glutamate N-acetyltransferase activity; arginine biosynthetic process; cytoplasm; glutamate N-acetyltransferase activity,PF01960;,,,,,,,,,ARGJ_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592] comp152544_c0_seq1,446,44.3946,0.50586674,9,0,,3.00E-49,Q9MZT1,"Chloride channel protein 1 (ClC-1) (Chloride channel protein, skeletal muscle)","Chloride channel protein 1 (ClC-1) (Chloride channel protein, skeletal muscle)",GO:0030554; GO:0034707; GO:0019227; GO:0042383; GO:0005247,adenyl nucleotide binding; chloride channel complex; neuronal action potential propagation; sarcolemma; voltage-gated chloride channel activity,PF00654;,2.00E-46,CHOYP_BRAFLDRAFT_118473.1.3,,,,,,,CLCN1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),chloride transmembrane transport [GO:1902476]; muscle contraction [GO:0006936]; neuronal action potential propagation [GO:0019227] comp152560_c0_seq1,213,37.5587,0.97528191,1,10,,,,,,,,,,,8.00E-26,ruditapes_c9255,,,,,,, comp152565_c0_seq1,219,70.7763,1.21488477,0,11,,8.00E-33,Q3IYX6,UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C),UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C),GO:0003677; GO:0009432; GO:0005737; GO:0009381; GO:0009380; GO:0006289,DNA binding; SOS response; cytoplasm; excinuclease ABC activity; excinuclease repair complex; nucleotide-excision repair,PF01541;PF02151;PF08459;,,,,,,,,,UVRC_RHOS4,Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158),nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432] comp152582_c0_seq1,297,46.1279,0.45152027,9,0,,8.00E-08,Q6V595,Kelch-like protein 6,Kelch-like protein 6,GO:0050853; GO:0002467,B cell receptor signaling pathway; germinal center formation,PF07707;PF00651;PF01344;,,,,,,,,,KLHL6_MOUSE,Mus musculus (Mouse),B cell receptor signaling pathway [GO:0050853]; germinal center formation [GO:0002467] comp152604_c0_seq1,436,37.6147,0.80331305,8,5,,6.00E-28,Q8IZN3,Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,5.00E-22,CHOYP_ZDHHC14.2.2,,,,,,,ZDH14_HUMAN,Homo sapiens (Human),protein palmitoylation [GO:0018345] comp152613_c0_seq1,451,43.6807,0.37293913,11,9,,2.00E-30,Q5PQJ7,Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35),Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35),GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF14560;,,,,,,,,,TBCEL_RAT,Rattus norvegicus (Rat), comp152620_c0_seq1,242,45.4545,0.26990465,2,9,,8.00E-34,Q61205,Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma),Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma),GO:0003847; GO:0007420; GO:0005737; GO:0005829; GO:0016042; GO:0007283,1-alkyl-2-acetylglycerophosphocholine esterase activity; brain development; cytoplasm; cytosol; lipid catabolic process; spermatogenesis,PF13472;,3.00E-22,CHOYP_PA1B2.1.2,,,,,,,PA1B3_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; lipid catabolic process [GO:0016042]; spermatogenesis [GO:0007283] comp152625_c0_seq1,313,44.7284,0.19260062,3,7,,5.00E-15,Q8R2E9,ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta),ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta),GO:0005789; GO:0016671; GO:0003756; GO:0006457,"endoplasmic reticulum membrane; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; protein disulfide isomerase activity; protein folding",PF04137;,5.00E-14,CHOYP_LOC592215.1.1,,,,,,,ERO1B_MOUSE,Mus musculus (Mouse),4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; insulin processing [GO:0030070]; protein maturation by protein folding [GO:0022417] comp152627_c0_seq1,297,49.1582,0.62689561,12,0,,2.00E-16,Q86VZ4,Low-density lipoprotein receptor-related protein 11 (LRP-11),Low-density lipoprotein receptor-related protein 11 (LRP-11),GO:0016021,integral to membrane,PF00057;PF07502;,,,,,,,,,LRP11_HUMAN,Homo sapiens (Human),multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414] comp152629_c0_seq1,261,47.1264,0.6386876,3,6,,3.00E-11,P41696,Asparagine-rich zinc finger protein AZF1,Asparagine-rich zinc finger protein AZF1,GO:0000978; GO:0001077; GO:0071322; GO:0005829; GO:0046872; GO:0005634; GO:0060237,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to carbohydrate stimulus; cytosol; metal ion binding; nucleus; regulation of fungal-type cell wall organization,PF13912;,,,,,,,,,AZF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp152643_c0_seq1,258,47.6744,0.97737317,3,9,,6.00E-09,Q61703,Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2),Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2),GO:0005576; GO:0030212; GO:0004867,extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,,,,,,,,,ITIH2_MOUSE,Mus musculus (Mouse),hyaluronan metabolic process [GO:0030212] comp152648_c0_seq1,246,41.4634,0.67120674,7,0,,2.00E-06,Q8WXS8,A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-),GO:0030574; GO:0030199; GO:0030198; GO:0005576; GO:0004222; GO:0005578; GO:0006508; GO:0008270,collagen catabolic process; collagen fibril organization; extracellular matrix organization; extracellular region; metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS14_HUMAN,Homo sapiens (Human),collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199] comp152664_c0_seq1,342,66.3743,1.11848782,3,13,,2.00E-32,Q9RKL4,Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase),Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase),GO:0006189; GO:0005524; GO:0000287; GO:0030145; GO:0004637; GO:0009113,'de novo' IMP biosynthetic process; ATP binding; magnesium ion binding; manganese ion binding; phosphoribosylamine-glycine ligase activity; purine nucleobase biosynthetic process,PF01071;PF02843;PF02844;,,,,,,,,,PUR2_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113] comp152675_c0_seq1,385,40.7792,0.45184251,10,0,,,,,,,,,,,6.00E-12,ruditapes2_lrc4297,,,,,,, comp152684_c0_seq1,218,38.0734,0,6,0,,2.00E-11,Q6AZW8,Zinc finger protein 660,Zinc finger protein 660,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN660_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp152687_c0_seq1,207,36.2319,0.30499246,0,10,,8.00E-10,Q9Y5W7,Sorting nexin-14,Sorting nexin-14,GO:0007154; GO:0016021; GO:0035091; GO:0015031; GO:0038032,cell communication; integral to membrane; phosphatidylinositol binding; protein transport; termination of G-protein coupled receptor signaling pathway,PF08628;PF00787;PF02194;PF00615;,5.00E-12,CHOYP_BRAFLDRAFT_275391.1.1,,,,,,,SNX14_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; protein transport [GO:0015031] comp152690_c0_seq1,290,42.7586,1.32878292,7,4,,7.00E-07,P13944,Collagen alpha-1(XII) chain (Fibrochimerin),Collagen alpha-1(XII) chain (Fibrochimerin),GO:0007155; GO:0005581,cell adhesion; collagen,PF01391;PF00041;PF00092;,,,,,,,,,COCA1_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155] comp152695_c0_seq1,205,45.8537,1.24851456,1,8,,4.00E-11,Q9BPW9,Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE),Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE),GO:0042904; GO:0004022; GO:0008209; GO:0030855; GO:0030176; GO:0042448; GO:0016854; GO:0004745; GO:0042572; GO:0047035,9-cis-retinoic acid biosynthetic process; alcohol dehydrogenase (NAD) activity; androgen metabolic process; epithelial cell differentiation; integral to endoplasmic reticulum membrane; progesterone metabolic process; racemase and epimerase activity; retinol dehydrogenase activity; retinol metabolic process; testosterone dehydrogenase (NAD+) activity,PF00106;,,,,,,,,,DHRS9_HUMAN,Homo sapiens (Human),9-cis-retinoic acid biosynthetic process [GO:0042904]; androgen metabolic process [GO:0008209]; epithelial cell differentiation [GO:0030855]; progesterone metabolic process [GO:0042448]; retinol metabolic process [GO:0042572] comp152703_c0_seq1,249,42.9719,1.04896797,2,9,,3.00E-14,P27216,Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA),Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA),GO:0005509; GO:0005544; GO:0030154; GO:0005886,calcium ion binding; calcium-dependent phospholipid binding; cell differentiation; plasma membrane,PF00191;,,,,,,,,,ANX13_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998] comp152722_c0_seq1,282,43.9716,0.73641311,0,11,,2.00E-24,Q62773,Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (rCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2),Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (rCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2),GO:0016021; GO:0001882; GO:0005415; GO:0034394; GO:0001895,integral to membrane; nucleoside binding; nucleoside:sodium symporter activity; protein localization to cell surface; retina homeostasis,PF07670;PF07662;PF01773;,,,,,,,,,S28A2_RAT,Rattus norvegicus (Rat),protein localization to cell surface [GO:0034394]; purine nucleoside transmembrane transport [GO:0015860]; retina homeostasis [GO:0001895] comp152724_c0_seq1,204,59.8039,0.88364192,4,7,,2.00E-07,O05586,Probable dolichyl-phosphate-mannose--protein mannosyltransferase (EC 2.4.1.109),,GO:0004169; GO:0040007; GO:0016021; GO:0005886; GO:0035269,dolichyl-phosphate-mannose-protein mannosyltransferase activity; growth; integral to membrane; plasma membrane; protein O-linked mannosylation,,,,,,,,,,Y1002_MYCTU,, comp152741_c0_seq1,290,41.3793,0.97109052,5,6,,,,,,,,,1.00E-33,CHOYP_KY.5.5,,,,,,,,, comp152749_c0_seq1,221,44.3439,0.94389688,0,11,,4.00E-23,Q498W5,Transmembrane protein 198-B,Transmembrane protein 198-B,GO:0016021,integral to membrane,PF13886;,6.00E-17,CHOYP_LOC100376630.1.1,,,,,,,T198B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp152756_c0_seq1,235,43.4043,1.46586505,7,0,,1.00E-20,P29476,"Nitric oxide synthase, brain (EC 1.14.13.39) (BNOS) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1)","Nitric oxide synthase, brain (EC 1.14.13.39) (BNOS) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1)",GO:0010181; GO:0050661; GO:0003958; GO:0007568; GO:0016597; GO:0006527; GO:0042582; GO:0048148; GO:0046870; GO:0005516; GO:0071260; GO:0005829; GO:0030425; GO:0043197; GO:0007565; GO:0050660; GO:0020037; GO:0005506; GO:0005741; GO:0006936; GO:0043066; GO:0045776; GO:0008285; GO:0045822; GO:0046676; GO:0045906; GO:0006809; GO:0007263; GO:0004517; GO:0031965; GO:0018119; GO:0048471; GO:0001917; GO:0031284; GO:1900273; GO:1901216; GO:1902307; GO:0045909; GO:0014069; GO:0043234; GO:0042803; GO:0051481; GO:0051930; GO:0014823; GO:0043627; GO:0045471; GO:0009408; GO:0001666; GO:0010288; GO:0032496; GO:0035094; GO:0071731; GO:0043434; GO:0033197; GO:0042383; GO:0017080; GO:0012506,FMN binding; NADP binding; NADPH-hemoprotein reductase activity; aging; amino acid binding; arginine catabolic process; azurophil granule; behavioral response to cocaine; cadmium ion binding; calmodulin binding; cellular response to mechanical stimulus; cytosol; dendrite; dendritic spine; female pregnancy; flavin adenine dinucleotide binding; heme binding; iron ion binding; mitochondrial outer membrane; muscle contraction; negative regulation of apoptotic process; negative regulation of blood pressure; negative regulation of cell proliferation; negative regulation of heart contraction; negative regulation of insulin secretion; negative regulation of vasoconstriction; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; nitric-oxide synthase activity; nuclear membrane; peptidyl-cysteine S-nitrosylation; perinuclear region of cytoplasm; photoreceptor inner segment; positive regulation of guanylate cyclase activity; positive regulation of long-term synaptic potentiation; positive regulation of neuron death; positive regulation of sodium ion transmembrane transport; positive regulation of vasodilation; postsynaptic density; protein complex; protein homodimerization activity; reduction of cytosolic calcium ion concentration; regulation of sensory perception of pain; response to activity; response to estrogen stimulus; response to ethanol; response to heat; response to hypoxia; response to lead ion; response to lipopolysaccharide; response to nicotine; response to nitric oxide; response to peptide hormone stimulus; response to vitamin E; sarcolemma; sodium channel regulator activity; vesicle membrane,PF00667;PF00258;PF00175;PF02898;PF00595;,,,,,,,,,NOS1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of insulin secretion [GO:0046676]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; positive regulation of vasodilation [GO:0045909]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197] comp152757_c0_seq1,213,46.9484,0.80251769,3,4,,9.00E-35,Q811Q9,Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B),Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B),GO:0006657; GO:0004105; GO:0005783; GO:0001541; GO:0007283,CDP-choline pathway; choline-phosphate cytidylyltransferase activity; endoplasmic reticulum; ovarian follicle development; spermatogenesis,PF01467;,1.00E-44,CHOYP_ISCW_ISCW012957.2.2,,,,,,,PCY1B_MOUSE,Mus musculus (Mouse),ovarian follicle development [GO:0001541]; spermatogenesis [GO:0007283] comp152758_c0_seq1,297,44.4444,0.35586742,4,4,,1.00E-17,Q86TP1,Protein prune homolog (hPrune) (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37),Protein prune homolog (hPrune) (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37),GO:0005737; GO:0005925; GO:0004427; GO:0030145; GO:0005634,cytoplasm; focal adhesion; inorganic diphosphatase activity; manganese ion binding; nucleus,PF01368;PF02833;,,,,,,,,,PRUNE_HUMAN,Homo sapiens (Human), comp152759_c0_seq1,279,60.2151,1.03542789,0,11,,5.00E-61,Q6A7Z2,Ketol-acid reductoisomerase (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacyl reductoisomerase),Ketol-acid reductoisomerase (NADP(+)) (KARI) (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (AHIR) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Ketol-acid reductoisomerase type 1) (Ketol-acid reductoisomerase type I),GO:0050662; GO:0009097; GO:0004455; GO:0009099,coenzyme binding; isoleucine biosynthetic process; ketol-acid reductoisomerase activity; valine biosynthetic process,PF01450;PF07991;,,,,,,,,,ILVC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] comp152786_c0_seq1,201,41.791,0.95061176,2,8,,8.00E-20,P33072,Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase),Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase),GO:0005507; GO:0005615; GO:0004720,copper ion binding; extracellular space; protein-lysine 6-oxidase activity,PF01186;,,,,,,,,,LYOX_BOVIN,Bos taurus (Bovine), comp152799_c0_seq1,290,36.8966,0.21508016,3,6,,3.00E-13,Q8BIQ8,Zinc finger protein 770,Zinc finger protein 770,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF13912;,,,,,,,,,ZN770_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp152809_c0_seq1,659,47.3445,0.55147186,18,12,,1.00E-72,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp152818_c0_seq1,286,45.4545,0.20456415,8,1,,4.00E-21,Q03468,DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),GO:0005524; GO:0003677; GO:0008094; GO:0007256; GO:0007257; GO:0006284; GO:0003682; GO:0004386; GO:0008630; GO:0035264; GO:0005730; GO:0045494; GO:0032786; GO:0032403; GO:0006290; GO:0009411; GO:0010224; GO:0010165; GO:0010332; GO:0006979; GO:0000303; GO:0009636; GO:0008023; GO:0006366; GO:0006283,"ATP binding; DNA binding; DNA-dependent ATPase activity; activation of JNKK activity; activation of JUN kinase activity; base-excision repair; chromatin binding; helicase activity; intrinsic apoptotic signaling pathway in response to DNA damage; multicellular organism growth; nucleolus; photoreceptor cell maintenance; positive regulation of DNA-dependent transcription, elongation; protein complex binding; pyrimidine dimer repair; response to UV; response to UV-B; response to X-ray; response to gamma radiation; response to oxidative stress; response to superoxide; response to toxic substance; transcription elongation factor complex; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF00271;PF00176;,,,,,,,,,ERCC6_HUMAN,Homo sapiens (Human),"activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]" comp152829_c0_seq1,290,47.5862,0.49946957,11,0,,,,,,,,,2.00E-18,CHOYP_BRAFLDRAFT_120904.1.1,,,,,,,,, comp152833_c0_seq1,205,39.0244,0.39515007,3,6,,1.00E-23,Q99PV3,Muskelin,Muskelin,GO:0005737,cytoplasm,PF01344;PF06588;,8.00E-22,CHOYP_MKLN1.1.1,,,,,,,MKLN1_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360] comp152843_c0_seq1,261,49.4253,0.63439188,11,0,,8.00E-09,P98156,Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),GO:0005509; GO:0008203; GO:0005905; GO:0005615; GO:0034436; GO:0034437; GO:0016021; GO:0006869; GO:0016020; GO:0000122; GO:1900006; GO:0045860; GO:0038025; GO:0021517; GO:0034361; GO:0034189; GO:0034447; GO:0030229,calcium ion binding; cholesterol metabolic process; coated pit; extracellular space; glycoprotein transport; glycoprotein transporter activity; integral to membrane; lipid transport; membrane; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite development; positive regulation of protein kinase activity; reelin receptor activity; ventral spinal cord development; very-low-density lipoprotein particle; very-low-density lipoprotein particle binding; very-low-density lipoprotein particle clearance; very-low-density lipoprotein particle receptor activity,PF07645;PF00057;PF00058;,,,,,,,,,VLDLR_MOUSE,Mus musculus (Mouse),cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex development [GO:0021987]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; heart development [GO:0007507]; lipid transport [GO:0006869]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] comp152874_c0_seq1,319,44.2006,1.04919064,1,11,,5.00E-13,Q04310,Uncharacterized protein SCO4629,Uncharacterized protein SCO4629,GO:0003677,DNA binding,PF02698;,,,,,,,,,Y4629_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145), comp152905_c0_seq1,220,43.6364,0.76871153,0,9,,6.00E-24,Q10751,Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),GO:0004180; GO:0016021; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,3.00E-15,CHOYP_LOC101076790.1.1,,,,,,,ACE_CHICK,Gallus gallus (Chicken), comp152909_c0_seq1,251,53.7849,0.81179383,7,2,,,,,,,,,2.00E-18,CHOYP_CRLF3.1.2,,,,,,,,, comp152920_c0_seq1,263,45.2471,0.60900534,9,2,,9.00E-07,O60500,Nephrin (Renal glomerulus-specific cell adhesion receptor),Nephrin (Renal glomerulus-specific cell adhesion receptor),GO:0007254; GO:0007155; GO:0042995; GO:0007588; GO:0032836; GO:0072015; GO:0005887; GO:0007520; GO:0030838; GO:0044062; GO:0007519; GO:0036057,JNK cascade; cell adhesion; cell projection; excretion; glomerular basement membrane development; glomerular visceral epithelial cell development; integral to plasma membrane; myoblast fusion; positive regulation of actin filament polymerization; regulation of excretion; skeletal muscle tissue development; slit diaphragm,PF08205;PF00041;PF07686;,,,,,,,,,NPHN_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; excretion [GO:0007588]; glomerular basement membrane development [GO:0032836]; glomerular visceral epithelial cell development [GO:0072015]; JNK cascade [GO:0007254]; myoblast fusion [GO:0007520]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to synapse [GO:0035418]; regulation of excretion [GO:0044062]; skeletal muscle tissue development [GO:0007519] comp152932_c0_seq1,208,56.25,1.0389129,0,11,,9.00E-08,Q08082,Putative transposase for insertion sequence element IS6501,Putative transposase for insertion sequence element IS6501,GO:0003677; GO:0006310; GO:0032196,DNA binding; DNA recombination; transposition,PF01609;,,,,,,,,,T6501_BRUO2,Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512),"transposition, DNA-mediated [GO:0006313]" comp152939_c0_seq1,203,48.2759,0.1705727,0,8,,3.00E-21,Q5F364,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_CHICK,Gallus gallus (Chicken), comp152957_c0_seq1,335,45.0746,0.47508377,15,0,,2.00E-12,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp152958_c0_seq1,410,48.5366,0.41599438,5,12,,1.00E-30,Q5EFZ4,Vacuolar protein 8,Vacuolar protein 8,GO:0005774; GO:0000011,vacuolar membrane; vacuole inheritance,PF00514;,,,,,,,,,VAC8_PICPA,Komagataella pastoris (Yeast) (Pichia pastoris), comp152959_c0_seq1,245,38.3673,0.2332898,10,2,,3.00E-13,Q5ZM13,Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A),Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A),GO:0005737; GO:0016020,cytoplasm; membrane,PF09790;,,,,,,,,,HYCCI_CHICK,Gallus gallus (Chicken),establishment of protein localization to plasma membrane [GO:0090002]; myelination [GO:0042552]; phosphatidylinositol phosphorylation [GO:0046854] comp152975_c0_seq1,251,41.8327,0.7368538,9,0,,2.00E-10,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp152993_c0_seq1,258,43.4109,0.91315474,0,12,,1.00E-17,Q92485,Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),GO:0005615; GO:0016798; GO:0006685; GO:0004767,"extracellular space; hydrolase activity, acting on glycosyl bonds; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity",PF00149;,,,,,,,,,ASM3B_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] comp153002_c0_seq1,245,44.4898,0.41498667,11,0,,8.00E-08,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp153011_c0_seq1,254,38.9764,0.85214353,9,0,,1.00E-05,P00980,Protease inhibitor 1 homolog (Alpha-dendrotoxin) (Alpha-DTX) (Toxin C13S2C3) (Venom basic protease inhibitor 1 homolog),Kunitz-type serine protease inhibitor homolog alpha-dendrotoxin (Alpha-DTX) (Protease inhibitor 1 homolog) (Toxin C13S2C3) (Venom basic protease inhibitor 1 homolog),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,IVBII_DENAN,Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps), comp153018_c0_seq1,205,22.9268,0.37455437,3,4,,,,,,,,,,,1.00E-16,ruditapes_lrc29467,,,,,,, comp153030_c0_seq1,343,48.3965,1.05614933,7,0,,1.00E-24,Q32LQ0,Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249),Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249),GO:0016477; GO:0008283; GO:0016021; GO:0070006; GO:0006508; GO:0003081; GO:0008270,cell migration; cell proliferation; integral to membrane; metalloaminopeptidase activity; proteolysis; regulation of systemic arterial blood pressure by renin-angiotensin; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPE_BOVIN,Bos taurus (Bovine),cell migration [GO:0016477]; cell proliferation [GO:0008283]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] comp153042_c0_seq1,214,43.9252,0.78756298,3,7,,1.00E-23,Q00449,Multidrug resistance protein homolog 49 (EC 3.6.3.44) (P-glycoprotein 49),Multidrug resistance protein homolog 49 (EC 3.6.3.44) (P-glycoprotein 49),GO:0005524; GO:0042626; GO:0015238; GO:0008354; GO:0005887; GO:0001666; GO:0031427; GO:0008559,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; drug transmembrane transporter activity; germ cell migration; integral to plasma membrane; response to hypoxia; response to methotrexate; xenobiotic-transporting ATPase activity",PF00664;PF00005;,5.00E-12,CHOYP_LOC582726.1.1,,,,,,,MDR49_DROME,Drosophila melanogaster (Fruit fly),drug transmembrane transport [GO:0006855]; germ cell migration [GO:0008354]; response to hypoxia [GO:0001666]; response to methotrexate [GO:0031427]; transmembrane transport [GO:0055085] comp153048_c0_seq1,218,62.3853,0.90301379,0,11,,7.00E-23,Q7VMI2,Ribosome-binding ATPase YchF,Ribosome-binding ATPase YchF,GO:0005524; GO:0005525,ATP binding; GTP binding,PF01926;PF06071;,,,,,,,,,ENGD_HAEDU,Haemophilus ducreyi (strain 35000HP / ATCC 700724), comp153052_c0_seq1,228,49.1228,0.67464473,7,0,,9.00E-30,Q9JIL5,Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF07525;PF01167;,1.00E-19,CHOYP_DPSE_GA18988.1.1,,,,,,,TULP4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567] comp153058_c0_seq1,209,48.3254,1.11887807,0,9,,4.00E-14,Q9U8W7,Techylectin-5B,Techylectin-5B,GO:0030246; GO:0016337; GO:0005576; GO:0046872,carbohydrate binding; cell-cell adhesion; extracellular region; metal ion binding,PF00147;,,,,,,,,,TL5B_TACTR,Tachypleus tridentatus (Japanese horseshoe crab),single organismal cell-cell adhesion [GO:0016337] comp153062_c0_seq1,299,46.4883,0.49896608,13,0,,2.00E-16,Q8CI95,Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11),GO:0005794; GO:0031902; GO:0006869; GO:0005543,Golgi apparatus; late endosome membrane; lipid transport; phospholipid binding,PF01237;PF00169;,,,,,,,,,OSB11_MOUSE,Mus musculus (Mouse),fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890] comp153071_c0_seq1,246,39.8374,0.42938563,5,10,,7.00E-07,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp153078_c0_seq1,232,48.7069,0.81366591,1,6,,4.00E-31,Q24352,Gamma-aminobutyric acid receptor alpha-like (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) (GRD),Gamma-aminobutyric acid receptor alpha-like (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) (GRD),GO:0004890; GO:0005261; GO:0030054; GO:0005254; GO:0034707; GO:0016933; GO:0016021; GO:0005886; GO:0045211,GABA-A receptor activity; cation channel activity; cell junction; chloride channel activity; chloride channel complex; extracellular-glycine-gated ion channel activity; integral to membrane; plasma membrane; postsynaptic membrane,PF02931;PF02932;,,,,,,,,,GBRAL_DROME,Drosophila melanogaster (Fruit fly),ion transport [GO:0006811] comp153089_c0_seq1,418,44.0191,0.54980632,16,0,,4.00E-10,F7J220,Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),GO:0030659; GO:0045087; GO:0016021; GO:0006909; GO:0005044,cytoplasmic vesicle membrane; innate immune response; integral to membrane; phagocytosis; scavenger receptor activity,PF00530;PF00084;,,,,,,,,,SRCR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),innate immune response [GO:0045087]; phagocytosis [GO:0006909] comp153092_c0_seq1,232,42.6724,0.6970215,3,7,,8.00E-18,Q8NBN7,Retinol dehydrogenase 13 (EC 1.1.1.-),Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3),GO:0005739; GO:0016491,mitochondrion; oxidoreductase activity,PF00106;,,,,,,,,,RDH13_HUMAN,Homo sapiens (Human),eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842] comp153095_c0_seq1,243,44.0329,0.42807742,4,3,,2.00E-08,P40818,Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),GO:0007265; GO:0001669; GO:0008283; GO:0004197; GO:0005829; GO:0005769; GO:0010008; GO:0007032; GO:0019897; GO:0030496; GO:0000281; GO:0005634; GO:0071108; GO:0070536; GO:0004221; GO:0006511; GO:0004843,Ras protein signal transduction; acrosomal vesicle; cell proliferation; cysteine-type endopeptidase activity; cytosol; early endosome; endosome membrane; endosome organization; extrinsic to plasma membrane; midbody; mitotic cytokinesis; nucleus; protein K48-linked deubiquitination; protein K63-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00581;PF00443;PF08969;,7.00E-17,CHOYP_LOC100367006.2.2,,,,,,,UBP8_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; endosome organization [GO:0007032]; ERBB2 signaling pathway [GO:0038128]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent protein catabolic process [GO:0006511] comp153106_c0_seq1,308,43.5065,0.56594003,7,3,,8.00E-09,Q9NPB8,Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5),Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5),GO:0005829; GO:0006071; GO:0047389; GO:0008889; GO:0046474; GO:0044281; GO:2001070,cytosol; glycerol metabolic process; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; glycerophospholipid biosynthetic process; small molecule metabolic process; starch binding,PF00686;PF03009;,,,,,,,,,GPCP1_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]; skeletal muscle tissue development [GO:0007519] comp153113_c0_seq1,289,60.5536,0.99211714,0,11,,2.00E-12,P94493,Putative metabolite transport protein YncC,Putative metabolite transport protein YncC,GO:0016021; GO:0005886; GO:0022891,integral to membrane; plasma membrane; substrate-specific transmembrane transporter activity,PF00083;,,,,,,,,,YNCC_BACSU,Bacillus subtilis (strain 168), comp153120_c0_seq1,215,66.5116,1.06259678,0,11,,7.00E-12,Q9LV03,"Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)","Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)",GO:0051538; GO:0010181; GO:0097054; GO:0019676; GO:0009570; GO:0048589; GO:0050660; GO:0006537; GO:0016040; GO:0005506; GO:0046686,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; ammonia assimilation cycle; chloroplast stroma; developmental growth; flavin adenine dinucleotide binding; glutamate biosynthetic process; glutamate synthase (NADH) activity; iron ion binding; response to cadmium ion",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,,,,,,,,,GLUT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),ammonia assimilation cycle [GO:0019676]; developmental growth [GO:0048589]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]; response to cadmium ion [GO:0046686]; response to cytokinin [GO:0009735] comp153125_c0_seq1,201,37.8109,0.70730042,9,0,,4.00E-08,Q9C0R2,,,,,,,,,,,,,,RTF22_SCHPO,, comp153130_c0_seq1,313,46.0064,0.30379567,10,1,,5.00E-21,Q9H7F0,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00689;PF00690;PF00122;PF12409;,6.00E-26,CHOYP_PHUM_PHUM193930.1.1,,,,,,,AT133_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874] comp153141_c0_seq1,227,48.8987,1.01369956,8,0,,3.00E-08,Q8CB67,Low-density lipoprotein receptor-related protein 11 (LRP-11),Low-density lipoprotein receptor-related protein 11 (LRP-11),GO:0006897; GO:0016021,endocytosis; integral to membrane,PF00057;PF07502;,,,,,,,,,LRP11_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414] comp153142_c0_seq1,310,45.8065,0.50569632,6,4,,7.00E-23,P97874,Cyclin-G-associated kinase (EC 2.7.11.1),Cyclin-G-associated kinase (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0007049; GO:0030332; GO:0005925; GO:0048471; GO:0004674,ATP binding; Golgi apparatus; cell cycle; cyclin binding; focal adhesion; perinuclear region of cytoplasm; protein serine/threonine kinase activity,PF00226;PF00069;PF10409;,,,,,,,,,GAK_RAT,Rattus norvegicus (Rat),cell cycle [GO:0007049]; receptor-mediated endocytosis [GO:0006898] comp153144_c0_seq1,288,37.8472,0.1950091,8,3,,1.00E-14,Q7Z2H8,Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1),Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1),GO:0015180; GO:0015193; GO:0006865; GO:0005783; GO:0015187; GO:0015078; GO:0016021; GO:0005765; GO:0005886; GO:0015293; GO:0055085,L-alanine transmembrane transporter activity; L-proline transmembrane transporter activity; amino acid transport; endoplasmic reticulum; glycine transmembrane transporter activity; hydrogen ion transmembrane transporter activity; integral to membrane; lysosomal membrane; plasma membrane; symporter activity; transmembrane transport,PF01490;,,,,,,,,,S36A1_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; glycine transport [GO:0015816]; ion transport [GO:0006811] comp153149_c0_seq1,251,41.4343,0.56000889,2,9,,3.00E-20,A8Y236,Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10),Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10),GO:0000139; GO:0016021; GO:0046872; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,1.00E-33,CHOYP_LOC100902628.1.1,,,,,,,GLT10_CAEBR,Caenorhabditis briggsae,protein glycosylation [GO:0006486] comp153185_c0_seq1,202,48.5149,1.18419569,0,9,,2.00E-06,Q9Y6L7,Tolloid-like protein 2 (EC 3.4.24.-),Tolloid-like protein 2 (EC 3.4.24.-),GO:0005509; GO:0030154; GO:0030198; GO:0005576; GO:0004222; GO:0007275; GO:0006508; GO:0008270,calcium ion binding; cell differentiation; extracellular matrix organization; extracellular region; metalloendopeptidase activity; multicellular organismal development; proteolysis; zinc ion binding,PF01400;PF00431;PF07645;,,,,,,,,,TLL2_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; multicellular organism development [GO:0007275]; negative regulation of skeletal muscle tissue growth [GO:0048632] comp153192_c0_seq1,304,40.4605,0.48774515,5,5,,8.00E-20,Q17QJ5,Tetraspanin-5 (Tspan-5),Tetraspanin-5 (Tspan-5),GO:0016021,integral to membrane,PF00335;,7.00E-12,CHOYP_LOC100645644.1.1,,,,,,,TSN5_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604] comp153195_c0_seq1,430,38.6047,0.63308215,8,2,,1.00E-21,Q94407,Nuclear hormone receptor family member nhr-48,Nuclear hormone receptor family member nhr-48,GO:0005634; GO:0043565; GO:0003700; GO:0043401; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone mediated signaling pathway; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00105;,5.00E-47,CHOYP_HR96.1.1,,,,,,,NHR48_CAEEL,Caenorhabditis elegans,"steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]" comp153237_c0_seq1,222,42.3423,1.086061,3,5,,2.00E-12,A8MXQ7,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,Putative IQ motif and ankyrin repeat domain-containing protein LOC642574,,,,2.00E-11,CHOYP_BRAFLDRAFT_128799.1.1,,,,,,,YH010_HUMAN,Homo sapiens (Human), comp153240_c0_seq1,217,51.1521,0.40371228,6,3,,,,,,,,,,,2.00E-22,ruditapes2_c2881,,,,,,, comp153246_c0_seq1,240,47.5,0.45401102,7,0,,1.00E-09,Q9W0T5,Transient receptor potential channel pyrexia,Transient receptor potential channel pyrexia,GO:0005262; GO:0034703; GO:0048060; GO:0051290; GO:0009408,calcium channel activity; cation channel complex; negative gravitaxis; protein heterotetramerization; response to heat,PF12796;PF00520;,,,,,,,,,PYX_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; cation transport [GO:0006812]; negative gravitaxis [GO:0048060]; protein heterotetramerization [GO:0051290]; response to heat [GO:0009408] comp153251_c0_seq1,258,44.5736,0.47177394,0,8,,2.00E-22,Q96JK2,DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22),DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22),GO:0080008; GO:0005739; GO:0016567,Cul4-RING ubiquitin ligase complex; mitochondrion; protein ubiquitination,PF00400;,2.00E-17,CHOYP_DCAF5.1.1,,,,,,,DCAF5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp153269_c0_seq1,379,36.6755,0.63492506,12,0,,7.00E-28,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,2.00E-77,CHOYP_NEMVEDRAFT_V1G244806.2.2,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp153277_c0_seq1,375,44.5333,0.46520591,4,10,,1.00E-09,Q14162,Scavenger receptor class F member 1 (Acetyl LDL receptor) (Scavenger receptor expressed by endothelial cells 1) (SREC-I),Scavenger receptor class F member 1 (Acetyl LDL receptor) (Scavenger receptor expressed by endothelial cells 1) (SREC-I),GO:0007155; GO:0006707; GO:0016358; GO:0030666; GO:0016021; GO:0030169; GO:0016322; GO:0005886; GO:0048680; GO:0005044; GO:0004888,cell adhesion; cholesterol catabolic process; dendrite development; endocytic vesicle membrane; integral to membrane; low-density lipoprotein particle binding; neuron remodeling; plasma membrane; positive regulation of axon regeneration; scavenger receptor activity; transmembrane signaling receptor activity,PF12661;PF00053;,,,,,,,,,SREC_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cholesterol catabolic process [GO:0006707]; dendrite development [GO:0016358]; neuron remodeling [GO:0016322]; positive regulation of axon regeneration [GO:0048680]; positive regulation of neuron projection development [GO:0010976]; receptor-mediated endocytosis [GO:0006898] comp153287_c0_seq1,215,46.0465,0.72667678,2,4,,3.00E-24,Q80U30,Protein CLEC16A,Protein CLEC16A,,,PF09758;,1.00E-20,CHOYP_LOC410511.2.2,,,,,,,CL16A_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; negative regulation of macromitophagy [GO:1901525]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of autophagosome maturation [GO:1901098] comp153295_c0_seq1,279,40.8602,0.4330399,9,0,,2.00E-08,Q6TGW5,Osteoclast-stimulating factor 1,Osteoclast-stimulating factor 1,GO:0005737,cytoplasm,PF12796;PF00018;,,,,,,,,,OSTF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp153310_c0_seq1,497,48.6922,0.44657696,14,0,,7.00E-21,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp153335_c0_seq1,306,44.1176,0.20932042,8,1,,2.00E-31,Q4R526,UPF0364 protein C6orf211 homolog,Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1),,,PF01937;,,,,,,,,,CF211_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cellular response to DNA damage stimulus [GO:0006974]; methylation [GO:0032259]; regulation of response to DNA damage stimulus [GO:2001020] comp153336_c0_seq1,330,34.5455,1.1293528,12,3,,5.00E-07,Q86567,Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3),Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3),GO:0005524; GO:0006200; GO:0042624; GO:0003677; GO:0006260; GO:0003723; GO:0003724; GO:0016888; GO:0042025; GO:0046872; GO:0090305; GO:0016779; GO:0018142,"ATP binding; ATP catabolic process; ATPase activity, uncoupled; DNA binding; DNA replication; RNA binding; RNA helicase activity; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; host cell nucleus; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleotidyltransferase activity; protein-DNA covalent cross-linking",PF00910;PF02407;,,,,,,,,,MREP_BBTVA,Banana bunchy top virus (isolate Autralia) (BBTV),protein-DNA covalent cross-linking [GO:0018142]; rolling circle single-stranded viral DNA replication [GO:0039684] comp153343_c0_seq1,230,51.3043,0.33420771,5,3,,3.00E-06,Q6JAN0,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),GO:0004930; GO:0042462; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; eye photoreceptor cell development; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF03160;,,,,,,,,,GPR98_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462] comp153349_c0_seq1,317,42.5868,0.42063911,11,0,,1.00E-37,A6H7C2,Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3),Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3),GO:0005779; GO:0007031,integral to peroxisomal membrane; peroxisome organization,PF04882;,5.00E-20,CHOYP_PEX3.1.1,,,,,,,PEX3_BOVIN,Bos taurus (Bovine),amino acid transmembrane transport [GO:0003333]; peroxisome organization [GO:0007031] comp153359_c0_seq1,210,48.5714,0.81249436,0,9,,4.00E-07,P82279,Protein crumbs homolog 1,Protein crumbs homolog 1,GO:0016324; GO:0005509; GO:0007267; GO:0007163; GO:0005576; GO:0042462; GO:0016021; GO:0005902; GO:0007009,apical plasma membrane; calcium ion binding; cell-cell signaling; establishment or maintenance of cell polarity; extracellular region; eye photoreceptor cell development; integral to membrane; microvillus; plasma membrane organization,PF00008;PF12661;PF02210;,,,,,,,,,CRUM1_HUMAN,Homo sapiens (Human),cell-cell signaling [GO:0007267]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; plasma membrane organization [GO:0007009] comp153369_c0_seq1,207,47.8261,0.51571451,1,9,,2.00E-20,A7S4N4,Probable serine incorporator,Probable serine incorporator,GO:0005789; GO:0016021; GO:0008654,endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process,PF03348;,8.00E-41,CHOYP_SERC1.1.1,,,,,,,SERIC_NEMVE,Nematostella vectensis (Starlet sea anemone),phospholipid biosynthetic process [GO:0008654] comp153372_c0_seq1,216,43.5185,0.40186047,4,3,,2.00E-06,Q9U2R6,Nuclear hormone receptor family member nhr-91,Nuclear hormone receptor family member nhr-91,GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,,,,,,,,,NHR91_CAEEL,Caenorhabditis elegans,"transcription, DNA-templated [GO:0006351]" comp153398_c0_seq1,210,40.4762,1.08516746,0,9,,2.00E-07,Q16518,Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase),Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase),GO:0052885; GO:0052884; GO:0071257; GO:0005783; GO:0008286; GO:0046872; GO:0031090; GO:0007603; GO:0005886; GO:0007468; GO:0060042; GO:0004744; GO:0042574; GO:0042572; GO:0007601; GO:0006776,"all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity; all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity; cellular response to electrical stimulus; endoplasmic reticulum; insulin receptor signaling pathway; metal ion binding; organelle membrane; phototransduction, visible light; plasma membrane; regulation of rhodopsin gene expression; retina morphogenesis in camera-type eye; retinal isomerase activity; retinal metabolic process; retinol metabolic process; visual perception; vitamin A metabolic process",PF03055;,,,,,,,,,RPE65_HUMAN,Homo sapiens (Human),cellular response to electrical stimulus [GO:0071257]; circadian rhythm [GO:0007623]; detection of light stimulus involved in visual perception [GO:0050908]; insulin receptor signaling pathway [GO:0008286]; neural retina development [GO:0003407]; regulation of rhodopsin gene expression [GO:0007468]; retina homeostasis [GO:0001895]; retinal metabolic process [GO:0042574]; retina morphogenesis in camera-type eye [GO:0060042]; retinoid metabolic process [GO:0001523]; visual perception [GO:0007601]; vitamin A metabolic process [GO:0006776] comp153402_c0_seq1,398,39.4472,0.32855939,9,4,,1.00E-63,Q6GNT9,Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1),Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1),,,PF01875;,7.00E-58,CHOYP_BRAFLDRAFT_114006.1.1,,,,,,,MEMO1_XENLA,Xenopus laevis (African clawed frog), comp153407_c0_seq1,204,47.549,1.31864232,9,0,,4.00E-17,P24733,"Myosin heavy chain, striated muscle","Myosin heavy chain, striated muscle",GO:0005524; GO:0003774; GO:0030016; GO:0032982,ATP binding; motor activity; myofibril; myosin filament,PF00063;PF02736;PF01576;,,,,,,,,,MYS_AEQIR,Argopecten irradians (Bay scallop) (Aequipecten irradians), comp153418_c0_seq1,281,39.8577,0.27011836,10,0,,2.00E-10,Q13075,Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),GO:0005524; GO:0016323; GO:0004869; GO:0005737; GO:0006954; GO:0045087; GO:0046872; GO:0043154; GO:0043524; GO:0007399; GO:0017111,ATP binding; basolateral plasma membrane; cysteine-type endopeptidase inhibitor activity; cytoplasm; inflammatory response; innate immune response; metal ion binding; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of neuron apoptotic process; nervous system development; nucleoside-triphosphatase activity,PF00653;,,,,,,,,,BIRC1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678] comp153419_c0_seq1,202,44.0594,0.62849837,5,0,,7.00E-07,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp153423_c0_seq1,207,40.5797,0.47273831,6,0,,1.00E-06,Q6DIY8,Mpv17-like protein 2,Mpv17-like protein 2,GO:0016021,integral to membrane,PF04117;,,,,,,,,,M17L2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp153431_c0_seq1,201,59.7015,0.73456364,0,3,,6.00E-18,P34737,40S ribosomal protein S15 (S12),40S ribosomal protein S15 (S12),GO:0003723; GO:0015935; GO:0003735; GO:0006412,RNA binding; small ribosomal subunit; structural constituent of ribosome; translation,PF00203;,3.00E-14,CHOYP_ISCW_ISCW016148.5.6,9.00E-19,ruditapes_lrc33878,,,,,RS15_PODAS,Podospora anserina (Pleurage anserina),translation [GO:0006412] comp153443_c0_seq1,294,44.898,1.15156327,4,7,,1.00E-11,O74549,NEDD8-conjugating enzyme ubc12 (EC 6.3.2.-) (RUB1-conjugating enzyme) (RUB1-protein ligase) (Ubiquitin carrier protein 12),NEDD8-conjugating enzyme ubc12 (EC 6.3.2.-) (RUB1-conjugating enzyme) (RUB1-protein ligase) (Ubiquitin carrier protein 12),GO:0005524; GO:0019788; GO:0005829; GO:0005634; GO:0045116; GO:0007346,ATP binding; NEDD8 ligase activity; cytosol; nucleus; protein neddylation; regulation of mitotic cell cycle,PF00179;,,,,,,,,,UBC12_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein neddylation [GO:0045116] comp153469_c0_seq1,248,60.8871,1.39840814,0,10,,7.00E-51,Q6A9W7,Octanoyltransferase (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase),Octanoyltransferase (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase),GO:0006464; GO:0005737; GO:0009107; GO:0033819; GO:0016415,cellular protein modification process; cytoplasm; lipoate biosynthetic process; lipoyl(octanoyl) transferase activity; octanoyltransferase activity,PF03099;,,,,,,,,,LIPB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cellular protein modification process [GO:0006464]; lipoate biosynthetic process [GO:0009107] comp153475_c0_seq1,224,41.5179,0.20833749,3,4,,1.00E-10,B1H2P5,Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),GO:0005737; GO:0005815,cytoplasm; microtubule organizing center,PF00168;PF12416;,,,,,,,,,CE120_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp153481_c0_seq1,355,43.3803,1.0214427,7,5,,4.00E-26,Q6P5U7,Leucine-rich repeat and WD repeat-containing protein KIAA1239,NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239),,,PF13271;,7.00E-32,CHOYP_LOC100744637.1.1,,,,,,,K1239_MOUSE,Mus musculus (Mouse), comp153500_c0_seq1,349,42.4069,0.31981257,8,4,,2.00E-20,Q5E9X5,AP-5 complex subunit mu-1 (Adapter-related protein complex 5 subunit mu-1) (Mu5),AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5),GO:0030119; GO:0030131; GO:0005829; GO:0016197; GO:0006886; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0016192,AP-type membrane coat adaptor complex; clathrin adaptor complex; cytosol; endosomal transport; intracellular protein transport; late endosome; late endosome membrane; lysosomal membrane; lysosome; vesicle-mediated transport,PF00928;,,,,,,,,,AP5M1_BOVIN,Bos taurus (Bovine),endosomal transport [GO:0016197]; protein transport [GO:0015031] comp153509_c0_seq1,293,44.7099,0.89091947,13,0,,,,,,,,,5.00E-14,CHOYP_AGAP_AGAP007127.1.1,,,,,,,,, comp153510_c0_seq1,243,41.1523,0.1001659,2,5,,4.00E-16,Q8K1R3,"Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)","Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)",GO:0000175; GO:0035458; GO:0034599; GO:0035198; GO:0000965; GO:0000964; GO:0045025; GO:0005758; GO:0000958; GO:0097222; GO:0070584; GO:0071850; GO:0045926; GO:0071042; GO:0005886; GO:0034046; GO:0008266; GO:0004654; GO:0061014; GO:2000627; GO:0000962; GO:0070207; GO:0035928; GO:0043457; GO:2000772,3'-5'-exoribonuclease activity; cellular response to interferon-beta; cellular response to oxidative stress; miRNA binding; mitochondrial RNA 3'-end processing; mitochondrial RNA 5'-end processing; mitochondrial degradosome; mitochondrial intermembrane space; mitochondrial mRNA catabolic process; mitochondrial mRNA polyadenylation; mitochondrion morphogenesis; mitotic cell cycle arrest; negative regulation of growth; nuclear polyadenylation-dependent mRNA catabolic process; plasma membrane; poly(G) RNA binding; poly(U) RNA binding; polyribonucleotide nucleotidyltransferase activity; positive regulation of mRNA catabolic process; positive regulation of miRNA catabolic process; positive regulation of mitochondrial RNA catabolic process; protein homotrimerization; rRNA import into mitochondrion; regulation of cellular respiration; regulation of cellular senescence,PF00013;PF03726;PF01138;PF03725;PF00575;,,,,,,,,,PNPT1_MOUSE,Mus musculus (Mouse),cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mitotic cell cycle arrest [GO:0071850]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928] comp153520_c0_seq1,231,49.7835,0.71385953,2,5,,7.00E-32,Q91428,Transcription factor GATA-3 (GATA-binding factor 3),Transcription factor GATA-3 (GATA-binding factor 3),GO:0060788; GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0021514; GO:0008270,"ectodermal placode formation; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ventral spinal cord interneuron differentiation; zinc ion binding",PF00320;,1.00E-14,CHOYP_GATA2.1.2,,,,,,,GATA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; digestive tract development [GO:0048565]; ectodermal placode development [GO:0071696]; ectodermal placode formation [GO:0060788]; embryonic neurocranium morphogenesis [GO:0048702]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fin regeneration [GO:0031101]; heart development [GO:0007507]; otic placode formation [GO:0043049]; positive regulation of cell proliferation [GO:0008284]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron migration [GO:2001224]; positive regulation of T cell differentiation [GO:0045582]; tissue regeneration [GO:0042246]; ventral spinal cord interneuron differentiation [GO:0021514] comp153524_c0_seq1,289,42.9066,0.6041739,9,0,,6.00E-10,Q9Y6R4,Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),GO:0005524; GO:0007254; GO:0004709; GO:0060718; GO:0005737; GO:0019100; GO:0046872; GO:0048471; GO:0001890; GO:0043507; GO:0010468,ATP binding; JNK cascade; MAP kinase kinase kinase activity; chorionic trophoblast cell differentiation; cytoplasm; male germ-line sex determination; metal ion binding; perinuclear region of cytoplasm; placenta development; positive regulation of JUN kinase activity; regulation of gene expression,PF00069;,,,,,,,,,M3K4_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] comp153529_c0_seq1,301,45.515,0.45345846,8,0,,1.00E-46,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,8.00E-62,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp153534_c0_seq1,244,45.4918,1.11437869,3,7,,6.00E-11,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,1.00E-13,CHOYP_BRAFLDRAFT_208197.14.21,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp153551_c0_seq1,346,41.9075,0.84738193,15,0,,4.00E-15,P48768,Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2),GO:1990034; GO:1990035; GO:0060402; GO:0005432; GO:0007154; GO:0043197; GO:0016021; GO:0005874; GO:0005739; GO:0043025; GO:0005886; GO:0033280; GO:0021537,calcium ion export from cell; calcium ion import into cell; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication; dendritic spine; integral to membrane; microtubule; mitochondrion; neuronal cell body; plasma membrane; response to vitamin D; telencephalon development,PF03160;PF01699;PF16494;,2.00E-19,CHOYP_BRAFLDRAFT_78683.4.4,,,,,,,NAC2_RAT,Rattus norvegicus (Rat),calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp153555_c0_seq1,287,46.3415,0.26386028,1,5,,2.00E-06,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp153556_c0_seq1,330,44.2424,0.24962522,11,0,,6.00E-19,A2RRH5,WD repeat-containing protein 27,WD repeat-containing protein 27,,,PF00400;,,,,,,,,,WDR27_HUMAN,Homo sapiens (Human), comp153607_c0_seq1,211,45.9716,0.55790727,0,7,,3.00E-29,O69077,Aspartokinase (EC 2.7.2.4) (Aspartate kinase),Aspartokinase (EC 2.7.2.4) (Aspartate kinase),GO:0005524; GO:0016597; GO:0004072; GO:0006520; GO:0019877; GO:0009089; GO:0009088,ATP binding; amino acid binding; aspartate kinase activity; cellular amino acid metabolic process; diaminopimelate biosynthetic process; lysine biosynthetic process via diaminopimelate; threonine biosynthetic process,PF00696;PF01842;PF13840;,,,,,,,,,AK_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088] comp153610_c0_seq1,205,34.1463,1.20169526,0,9,,2.00E-16,P0A9V4,Lipopolysaccharide export system ATP-binding protein LptB (EC 3.6.3.-),Lipopolysaccharide export system ATP-binding protein LptB (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0005737; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; cytoplasm; plasma membrane; transport,PF00005;PF12399;,,,,,,,,,LPTB_SHIFL,Shigella flexneri,transmembrane transport [GO:0055085] comp153618_c0_seq1,269,53.1599,0.15863909,10,0,,2.00E-31,P05982,NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1),NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1),GO:0003955; GO:0007568; GO:0005829; GO:0043086; GO:0043025; GO:0043525; GO:0032355; GO:0045471; GO:0007584; GO:0006979; GO:0004784; GO:0006801,NAD(P)H dehydrogenase (quinone) activity; aging; cytosol; negative regulation of catalytic activity; neuronal cell body; positive regulation of neuron apoptotic process; response to estradiol stimulus; response to ethanol; response to nutrient; response to oxidative stress; superoxide dismutase activity; superoxide metabolic process,PF02525;,,,,,,,,,NQO1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801] comp153622_c0_seq1,282,40.0709,0.81219134,5,2,,6.00E-12,Q9Y5E4,Protocadherin beta-5 (PCDH-beta-5),Protocadherin beta-5 (PCDH-beta-5),GO:0005509; GO:0016339; GO:0007156; GO:0016021; GO:0005886; GO:0007416; GO:0007268,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to membrane; plasma membrane; synapse assembly; synaptic transmission,PF00028;PF08266;PF16492;,,,,,,,,,PCDB5_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416] comp153647_c0_seq1,278,38.1295,0.49733264,7,0,,1.00E-21,Q96JG6,Coiled-coil domain-containing protein 132,Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50),,,PF10474;PF10475;,2.00E-12,CHOYP_CC132.1.1,,,,,,,CC132_HUMAN,Homo sapiens (Human),endocytic recycling [GO:0032456]; protein transport [GO:0015031] comp153657_c0_seq1,226,60.6195,1.02254254,8,0,,,,,,,,,3.00E-14,CHOYP_RNA45S5.4.4,,,,,,,,, comp153665_c0_seq1,329,41.3374,1.36068965,7,1,,6.00E-11,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp153669_c0_seq1,214,62.1495,1.37445924,0,10,,4.00E-22,P75691,Uncharacterized zinc-type alcohol dehydrogenase-like protein YahK (EC 1.-.-.-),Aldehyde reductase YahK (EC 1.1.1.2) (Zinc-dependent alcohol dehydrogenase YahK),GO:0008106; GO:0048037; GO:0008270,alcohol dehydrogenase (NADP+) activity; cofactor binding; zinc ion binding,PF08240;PF00107;,,,,,,,,,YAHK_ECOLI,Escherichia coli (strain K12), comp153708_c0_seq1,206,41.7476,0.56466142,8,0,,4.00E-11,O15357,"Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)","Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)",GO:0005794; GO:0007015; GO:0007420; GO:0007155; GO:0005856; GO:0005829; GO:0001958; GO:0006897; GO:0030175; GO:0006006; GO:0043647; GO:0032957; GO:0004445; GO:0030027; GO:0008156; GO:0043407; GO:0008285; GO:0010629; GO:0046627; GO:0043569; GO:0010977; GO:0010642; GO:0006661; GO:0046856; GO:0005547; GO:0005886; GO:0009791; GO:0042493; GO:0032868; GO:0097178,"Golgi apparatus; actin filament organization; brain development; cell adhesion; cytoskeleton; cytosol; endochondral ossification; endocytosis; filopodium; glucose metabolic process; inositol phosphate metabolic process; inositol trisphosphate metabolic process; inositol-polyphosphate 5-phosphatase activity; lamellipodium; negative regulation of DNA replication; negative regulation of MAP kinase activity; negative regulation of cell proliferation; negative regulation of gene expression; negative regulation of insulin receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of neuron projection development; negative regulation of platelet-derived growth factor receptor signaling pathway; phosphatidylinositol biosynthetic process; phosphatidylinositol dephosphorylation; phosphatidylinositol-3,4,5-trisphosphate binding; plasma membrane; post-embryonic development; response to drug; response to insulin stimulus; ruffle assembly",PF03372;PF00536;PF00017;,,,,,,,,,SHIP2_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178] comp153713_c0_seq1,207,29.4686,0.89464453,8,0,,,,,,,,,3.00E-15,CHOYP_LOC100537145.3.3,,,,,,,,, comp153714_c0_seq1,262,48.0916,0.39758705,2,9,,2.00E-21,Q9HCK4,Roundabout homolog 2,Roundabout homolog 2,GO:0061364; GO:0030673; GO:0008046; GO:0016199; GO:0009986; GO:0032870; GO:0007156; GO:0042802; GO:0016021; GO:0001656; GO:0050925; GO:0051964; GO:0021891; GO:0050772; GO:0031290; GO:0001657,apoptotic process involved in luteolysis; axolemma; axon guidance receptor activity; axon midline choice point recognition; cell surface; cellular response to hormone stimulus; homophilic cell adhesion; identical protein binding; integral to membrane; metanephros development; negative regulation of negative chemotaxis; negative regulation of synapse assembly; olfactory bulb interneuron development; positive regulation of axonogenesis; retinal ganglion cell axon guidance; ureteric bud development,PF00041;PF07679;,,,,,,,,,ROBO2_HUMAN,Homo sapiens (Human),apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657] comp153736_c0_seq1,310,32.9032,0,8,3,,,,,,,,,,,9.00E-15,ruditapes_c5711,,,,,,, comp153768_c0_seq1,242,46.6942,0.6864524,8,0,,5.00E-09,P47990,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0030151; GO:0043546; GO:0005777; GO:0034418; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; peroxisome; urate biosynthetic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_CHICK,Gallus gallus (Chicken),urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] comp153790_c0_seq1,212,49.5283,0.15525127,4,3,,9.00E-11,Q5JWR5,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,6.00E-17,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp153801_c0_seq1,302,40.0662,0.51211829,9,0,,9.00E-19,Q9UHC1,DNA mismatch repair protein Mlh3 (MutL protein homolog 3),DNA mismatch repair protein Mlh3 (MutL protein homolog 3),GO:0005524; GO:0016887; GO:0032390; GO:0032407; GO:0019237; GO:0005712; GO:0003682; GO:0007144; GO:0001673; GO:0007140; GO:0006298; GO:0030983; GO:0008104; GO:0007131; GO:0003696; GO:0003697; GO:0000795; GO:0007130,ATP binding; ATPase activity; MutLbeta complex; MutSalpha complex binding; centromeric DNA binding; chiasma; chromatin binding; female meiosis I; male germ cell nucleus; male meiosis; mismatch repair; mismatched DNA binding; protein localization; reciprocal meiotic recombination; satellite DNA binding; single-stranded DNA binding; synaptonemal complex; synaptonemal complex assembly,PF01119;PF08676;,,,,,,,,,MLH3_HUMAN,Homo sapiens (Human),female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] comp153817_c0_seq1,279,40.1434,0.98340982,4,4,,6.00E-07,Q96JK2,DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22),DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22),GO:0080008; GO:0005739; GO:0016567,Cul4-RING ubiquitin ligase complex; mitochondrion; protein ubiquitination,PF00400;,,,,,,,,,DCAF5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp153878_c0_seq1,212,44.3396,0.30299394,7,0,,2.00E-10,O70173,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma),Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma),GO:0016303; GO:0035005; GO:0005524; GO:0005794; GO:0006935; GO:0005635; GO:0005942; GO:0035091; GO:0048015; GO:0005886,1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; Golgi apparatus; chemotaxis; nuclear envelope; phosphatidylinositol 3-kinase complex; phosphatidylinositol binding; phosphatidylinositol-mediated signaling; plasma membrane,PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;,5.00E-12,CHOYP_LOC100121969.1.1,,,,,,,P3C2G_RAT,Rattus norvegicus (Rat),chemotaxis [GO:0006935]; phosphatidylinositol-mediated signaling [GO:0048015] comp153897_c0_seq1,207,75.3623,1.02583357,0,8,,8.00E-11,Q8PC99,Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.n16) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC),Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC),GO:0003676; GO:0018364; GO:0036009,nucleic acid binding; peptidyl-glutamine methylation; protein-glutamine N-methyltransferase activity,PF05175;,,,,,,,,,PRMC_XANCP,Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25),peptidyl-glutamine methylation [GO:0018364] comp153917_c0_seq1,469,40.9382,0.15314504,8,9,,2.00E-50,Q3UVG3,Protein FAM91A1,Protein FAM91A1,,,PF14648;PF14647;,3.00E-37,CHOYP_F91A1.1.1,,,,,,,F91A1_MOUSE,Mus musculus (Mouse), comp153919_c0_seq1,341,44.868,0.76000654,8,0,,1.00E-29,P41234,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0016887; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0005765; GO:0005815; GO:0032383; GO:0006357; GO:0048545; GO:0006810,ATP binding; ATPase activity; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lysosomal membrane; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to steroid hormone stimulus; transport,PF00005;,4.00E-16,CHOYP_ABCA3.5.6,,,,,,,ABCA2_MOUSE,Mus musculus (Mouse),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545] comp153942_c0_seq1,262,50,0.98549445,7,4,,1.00E-13,A8MV24,Uncharacterized protein C17orf98,Uncharacterized protein C17orf98,,,PF15075;,,,,,,,,,CQ098_HUMAN,Homo sapiens (Human), comp153956_c0_seq1,264,39.7727,1.21190763,5,5,,8.00E-21,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp153958_c0_seq1,420,41.4286,0.78128757,10,0,,1.00E-25,P24792,L-ascorbate oxidase (ASO) (Ascorbase) (EC 1.10.3.3),L-ascorbate oxidase (ASO) (Ascorbase) (EC 1.10.3.3),GO:0008447; GO:0005507; GO:0005576,L-ascorbate oxidase activity; copper ion binding; extracellular region,PF00394;PF07731;PF07732;,3.00E-11,CHOYP_LOC584333.1.1,,,,,,,ASO_CUCMA,Cucurbita maxima (Pumpkin) (Winter squash), comp153961_c0_seq1,448,45.7589,0.57225775,7,6,,5.00E-53,A8Y236,Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10),Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10),GO:0000139; GO:0016021; GO:0046872; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,2.00E-77,CHOYP_LOC100902628.1.1,,,,,,,GLT10_CAEBR,Caenorhabditis briggsae,protein glycosylation [GO:0006486] comp153973_c0_seq1,281,51.6014,0.59086463,5,4,,3.00E-16,Q7TPD3,Roundabout homolog 2,Roundabout homolog 2,GO:0030673; GO:0016199; GO:0009986; GO:0007156; GO:0042802; GO:0016021; GO:0001656; GO:0021891; GO:0050772; GO:0031290; GO:0001657,axolemma; axon midline choice point recognition; cell surface; homophilic cell adhesion; identical protein binding; integral to membrane; metanephros development; olfactory bulb interneuron development; positive regulation of axonogenesis; retinal ganglion cell axon guidance; ureteric bud development,PF00041;PF07679;,,,,,,,,,ROBO2_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657] comp153982_c0_seq1,226,38.4956,0.37092229,4,3,,1.00E-25,Q9NRW7,Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45),Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45),GO:0005794; GO:0000139; GO:0007596; GO:0010008; GO:0016021; GO:0006886; GO:0006904,Golgi apparatus; Golgi membrane; blood coagulation; endosome membrane; integral to membrane; intracellular protein transport; vesicle docking involved in exocytosis,PF00995;,5.00E-44,CHOYP_VPS45.1.1,,,,,,,VPS45_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; intracellular protein transport [GO:0006886]; vesicle docking involved in exocytosis [GO:0006904] comp154003_c0_seq1,238,50.8403,0.33158188,6,0,,3.00E-22,Q9UPU5,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,2.00E-23,CHOYP_UBP24.1.1,,,,,,,UBP24_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp154008_c0_seq1,265,43.7736,0.5741679,6,0,,3.00E-06,Q9ES34,Ubiquitin-protein ligase E3B (EC 6.3.2.-),Ubiquitin-protein ligase E3B (EC 6.3.2.-),GO:0005737; GO:0005634; GO:0042787; GO:0004842,cytoplasm; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;PF00612;,,,,,,,,,UBE3B_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp154018_c0_seq1,270,48.5185,0.57254307,4,2,,3.00E-09,Q8T674,ABC transporter G family member 20 (ABC transporter ABCG.20),ABC transporter G family member 20 (ABC transporter ABCG.20),GO:0005524; GO:0043190; GO:0042626; GO:0016021,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; integral to membrane",PF00005;,,,,,,,,,ABCGK_DICDI,Dictyostelium discoideum (Slime mold),transport [GO:0006810] comp154022_c0_seq1,204,42.6471,0.5688261,7,0,,4.00E-20,Q6TCG8,Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG),Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG),GO:0000139; GO:0016021,Golgi membrane; integral to membrane,PF03006;,6.00E-30,CHOYP_BRAFLDRAFT_62482.1.1,,,,,,,PAQR3_MOUSE,Mus musculus (Mouse),negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein phosphorylation [GO:0001933]; protein localization to Golgi apparatus [GO:0034067] comp154030_c0_seq1,258,49.2248,0.71656006,8,0,,6.00E-13,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp154078_c0_seq1,206,41.2621,1.20632213,6,0,,4.00E-07,Q96XY5,Uncharacterized protein STK_23830,Uncharacterized protein STK_23830,,,PF01661;,,,,,,,,,Y2383_SULTO,Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7), comp154090_c0_seq1,209,35.4067,0.6153987,1,6,,5.00E-07,O54905,"Beta-1,3-galactosyltransferase 2 (Beta-1,3-GalTase 2) (Beta3Gal-T2) (Beta3GalT2) (EC 2.4.1.-) (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II)","Beta-1,3-galactosyltransferase 2 (Beta-1,3-GalTase 2) (Beta3Gal-T2) (Beta3GalT2) (EC 2.4.1.-) (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II)",GO:0000139; GO:0008499; GO:0016021; GO:0009312; GO:0006486,"Golgi membrane; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; integral to membrane; oligosaccharide biosynthetic process; protein glycosylation",PF01762;,,,,,,,,,B3GT2_MOUSE,Mus musculus (Mouse),oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] comp154103_c0_seq1,285,47.7193,1.40888434,4,4,,,,,,,,,,,1.00E-12,ruditapes2_c811,,,,,,, comp154106_c0_seq1,291,46.0481,0.35705973,4,4,,4.00E-18,Q86VE9,Serine incorporator 5,Serine incorporator 5,GO:0005794; GO:0005789; GO:0016021; GO:0043209; GO:0042552; GO:0006658; GO:0008654; GO:0051347,Golgi apparatus; endoplasmic reticulum membrane; integral to membrane; myelin sheath; myelination; phosphatidylserine metabolic process; phospholipid biosynthetic process; positive regulation of transferase activity,PF03348;,,,,,,,,,SERC5_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; myelination [GO:0042552]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222]; sphingolipid metabolic process [GO:0006665]; viral process [GO:0016032] comp154132_c0_seq1,267,53.5581,0.47369086,4,3,,6.00E-11,Q6ZMP0,Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6),Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6),GO:0048251; GO:0004222; GO:0001527,elastic fiber assembly; metalloendopeptidase activity; microfibril,PF05986;PF08686;PF00090;,,,,,,,,,THSD4_HUMAN,Homo sapiens (Human),elastic fiber assembly [GO:0048251] comp154151_c0_seq1,204,33.3333,0.54377964,2,5,,5.00E-23,Q9NRW4,Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x),Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x),GO:0006915; GO:0008283; GO:0005737; GO:0000188; GO:0007275; GO:0000122; GO:0005634; GO:0035335; GO:0046330; GO:0004725; GO:0008138; GO:0042127; GO:0007179,apoptotic process; cell proliferation; cytoplasm; inactivation of MAPK activity; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; nucleus; peptidyl-tyrosine dephosphorylation; positive regulation of JNK cascade; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; regulation of cell proliferation; transforming growth factor beta receptor signaling pathway,PF00782;,2.00E-16,CHOYP_DANA_GF10970.1.1,,,,,,,DUS22_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; inactivation of MAPK activity [GO:0000188]; multicellular organism development [GO:0007275]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of JNK cascade [GO:0046330]; protein dephosphorylation [GO:0006470]; regulation of cell proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp154155_c0_seq1,205,45.3659,0.76652987,6,0,,2.00E-08,D4A8G9,Zinc finger FYVE domain-containing protein 26,Zinc finger FYVE domain-containing protein 26,GO:0006281; GO:0005813; GO:0000910; GO:0005737; GO:0046872; GO:0030496; GO:0032266,DNA repair; centrosome; cytokinesis; cytoplasm; metal ion binding; midbody; phosphatidylinositol-3-phosphate binding,PF01363;,,,,,,,,,ZFY26_RAT,Rattus norvegicus (Rat),cytokinesis [GO:0000910]; double-strand break repair via homologous recombination [GO:0000724] comp154163_c0_seq1,402,45.0249,0.34528977,6,6,,2.00E-43,Q8IZU2,WD repeat-containing protein 17,WD repeat-containing protein 17,,,PF12894;PF00400;,2.00E-15,CHOYP_WDR17.1.1,,,,,,,WDR17_HUMAN,Homo sapiens (Human), comp154171_c0_seq1,309,52.1036,0.39067832,10,0,,4.00E-37,Q2KJY2,Kinesin-like protein KIF26B,Kinesin-like protein KIF26B,GO:0005524; GO:0005737; GO:0030010; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0022409; GO:0072092,ATP binding; cytoplasm; establishment of cell polarity; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; positive regulation of cell-cell adhesion; ureteric bud invasion,PF00225;,2.00E-37,CHOYP_KIF26A.1.1,,,,,,,KI26B_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; establishment of cell polarity [GO:0030010]; positive regulation of cell-cell adhesion [GO:0022409]; protein localization [GO:0008104]; ureteric bud invasion [GO:0072092] comp154192_c0_seq1,367,41.1444,0.64584544,10,2,,4.00E-21,Q5DRB6,Protocadherin gamma-A4 (PCDH-gamma-A4),Protocadherin gamma-A4 (PCDH-gamma-A4),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG4_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp154197_c0_seq1,393,39.1858,0.20278052,12,0,,,,,,,,,,,7.00E-11,ruditapes_c5291,,,,,,, comp154202_c0_seq1,383,46.9974,0.38309277,11,0,,3.00E-19,Q63191,Apical endosomal glycoprotein (MAM domain-containing protein 4),Apical endosomal glycoprotein (MAM domain-containing protein 4),GO:0005768; GO:0016021; GO:0015031,endosome; integral to membrane; protein transport,PF00057;PF00629;,3.00E-11,CHOYP_LOC580670.1.6,,,,,,,AEGP_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp154208_c0_seq1,374,43.8503,0.34620958,4,7,,3.00E-35,Q2LAM0,Fatty acid 2-hydroxylase (EC 1.-.-.-) (Fatty acid alpha-hydroxylase),Fatty acid 2-hydroxylase (EC 1.-.-.-) (Fatty acid alpha-hydroxylase),GO:0032286; GO:0005789; GO:0080132; GO:0006633; GO:0020037; GO:0016021; GO:0005506; GO:0030258; GO:0032287; GO:0042127; GO:0042634; GO:0001949; GO:0006665,central nervous system myelin maintenance; endoplasmic reticulum membrane; fatty acid alpha-hydroxylase activity; fatty acid biosynthetic process; heme binding; integral to membrane; iron ion binding; lipid modification; peripheral nervous system myelin maintenance; regulation of cell proliferation; regulation of hair cycle; sebaceous gland cell differentiation; sphingolipid metabolic process,PF00173;PF04116;,7.00E-13,CHOYP_BRAFLDRAFT_65126.1.1,,,,,,,FA2H_RAT,Rattus norvegicus (Rat),central nervous system myelin maintenance [GO:0032286]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; lipid modification [GO:0030258]; peripheral nervous system myelin maintenance [GO:0032287]; regulation of cell proliferation [GO:0042127]; regulation of hair cycle [GO:0042634]; sebaceous gland cell differentiation [GO:0001949] comp154209_c0_seq1,239,37.2385,0.36364273,6,2,,1.00E-14,Q2VY69,Zinc finger protein 284,Zinc finger protein 284,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN284_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp154212_c0_seq1,246,50,0.19603499,9,0,,5.00E-18,Q9VTK2,Protein O-mannosyltransferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1) (dPOMT1) (Protein rotated abdomen),Protein O-mannosyltransferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1) (dPOMT1) (Protein rotated abdomen),GO:0004169; GO:0005783; GO:0005789; GO:0016021; GO:0030259; GO:0016203; GO:0035269; GO:0060025; GO:0045214; GO:0007525; GO:0007385,"dolichyl-phosphate-mannose-protein mannosyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; lipid glycosylation; muscle attachment; protein O-linked mannosylation; regulation of synaptic activity; sarcomere organization; somatic muscle development; specification of segmental identity, abdomen",PF02815;PF02366;PF16192;,9.00E-16,CHOYP_LOC100871274.1.1,,,,,,,POMT1_DROME,Drosophila melanogaster (Fruit fly),"cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; lipid glycosylation [GO:0030259]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; protein O-linked mannosylation [GO:0035269]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; regulation of synaptic activity [GO:0060025]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; specification of segmental identity, abdomen [GO:0007385]" comp154234_c0_seq1,212,42.9245,0.20882818,7,0,,8.00E-25,Q5TYW4,Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),GO:0009790; GO:0000184,"embryo development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",PF15492;PF08314;,,,,,,,,,NBAS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp154249_c0_seq1,381,51.4436,0.75857546,15,0,,,,,,,,,,,9.00E-16,ruditapes2_c559,,,,,,, comp154259_c0_seq1,331,41.6918,0.27946383,12,0,,2.00E-25,O08684,Phospholipase D1 (PLD 1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),Phospholipase D1 (PLD 1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),GO:0000139; GO:0070290; GO:0007154; GO:0005789; GO:0031902; GO:0016042; GO:0048471; GO:0035091; GO:0004630,Golgi membrane; NAPE-specific phospholipase D activity; cell communication; endoplasmic reticulum membrane; late endosome membrane; lipid catabolic process; perinuclear region of cytoplasm; phosphatidylinositol binding; phospholipase D activity,PF00169;PF00614;PF13091;PF00787;,,,,,,,,,PLD1_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764] comp154268_c0_seq1,210,61.9048,0.95250437,0,9,,7.00E-21,O50465,Uncharacterized MFS-type transporter Rv1250/MT1289,,GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,,,,,,,,,,Y1250_MYCTU,, comp154286_c0_seq1,325,42.1538,0.70319906,10,0,,,,,,,,,8.00E-12,CHOYP_BRAFLDRAFT_131608.1.1,,,,,,,,, comp154301_c0_seq1,232,33.6207,0.3096403,7,0,,,,,,,,,6.00E-18,CHOYP_LOC100892023.1.1,,,,,,,,, comp154317_c0_seq1,293,45.7338,0.59274884,12,0,,2.00E-43,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,8.00E-43,CHOYP_BTBD2.1.1,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp154325_c0_seq1,268,41.0448,0.71353779,6,0,,8.00E-16,Q6ZPR4,Potassium channel subfamily T member 1,Potassium channel subfamily T member 1,GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,2.00E-23,CHOYP_LOC655919.1.1,,,,,,,KCNT1_MOUSE,Mus musculus (Mouse), comp154329_c0_seq1,204,63.2353,1.24094992,0,7,,2.00E-15,O94467,Putative NADPH dehydrogenase C23G7.10c (EC 1.6.99.1) (Old yellow enzyme homolog 3),Putative NADPH dehydrogenase C23G7.10c (EC 1.6.99.1) (Old yellow enzyme homolog 3),GO:0010181; GO:0003959; GO:0005829; GO:0006091; GO:0005634; GO:0018548; GO:0052690,FMN binding; NADPH dehydrogenase activity; cytosol; generation of precursor metabolites and energy; nucleus; pentaerythritol trinitrate reductase activity; trichloro-p-hydroquinone reductive dehalogenase activity,PF00724;,,,,,,,,,OYEC_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),oxidation-reduction process [GO:0055114] comp154334_c0_seq1,201,44.2786,0.1049922,7,0,,3.00E-17,Q5VV63,Attractin-like protein 1,Attractin-like protein 1,GO:0007186; GO:0030246; GO:0016021; GO:0007275; GO:0004872,G-protein coupled receptor signaling pathway; carbohydrate binding; integral to membrane; multicellular organismal development; receptor activity,PF00431;PF07974;PF01344;PF00059;PF01437;,,,,,,,,,ATRN1_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186] comp154357_c0_seq1,214,51.8692,0.97729407,2,3,,2.00E-06,Q7ZWG6,Proton-coupled folate transporter (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1),Proton-coupled folate transporter (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1),GO:0005542; GO:0016021; GO:0055085,folic acid binding; integral to membrane; transmembrane transport,PF07690;,,,,,,,,,PCFT_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),transmembrane transport [GO:0055085] comp154380_c0_seq1,249,45.7831,0.23148522,8,0,,3.00E-17,Q9Y6Y1,Calmodulin-binding transcription activator 1,Calmodulin-binding transcription activator 1,GO:0003677; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03859;PF00612;PF01833;,,,,,,,,,CMTA1_HUMAN,Homo sapiens (Human),neuromuscular process controlling balance [GO:0050885]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp154386_c0_seq1,467,43.6831,0.18036502,15,2,,6.00E-11,Q5RKH1,Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog),Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog),GO:0005524; GO:0008380; GO:0071013; GO:0005694; GO:0006397; GO:0004674,ATP binding; RNA splicing; catalytic step 2 spliceosome; chromosome; mRNA processing; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PRP4B_RAT,Rattus norvegicus (Rat),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp154387_c0_seq1,374,44.9198,1.12388416,10,0,,3.00E-09,P86860,Shell matrix protein (Fragment),Shell matrix protein (Fragment),GO:0005576,extracellular region,,,,,,,,,,PSM_MYTCA,Mytilus californianus (California mussel), comp154396_c0_seq1,249,47.3896,0.37459399,7,2,,,,,,,,,7.00E-11,CHOYP_BRAFLDRAFT_87529.1.3,,,,,,,,, comp154401_c0_seq1,320,37.1875,0.27640913,8,0,,1.00E-08,Q9SXD9,Flavin-containing monooxygenase FMO GS-OX-like 7 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 7),Flavin-containing monooxygenase FMO GS-OX-like 7 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 7),GO:0004499; GO:0050661; GO:0050660,"N,N-dimethylaniline monooxygenase activity; NADP binding; flavin adenine dinucleotide binding",PF00743;,,,,,,,,,GSXL7_ARATH,Arabidopsis thaliana (Mouse-ear cress),oxidation-reduction process [GO:0055114] comp154405_c0_seq1,281,38.0783,0.59244448,2,5,,2.00E-18,Q6DN14,Multiple C2 and transmembrane domain-containing protein 1,Multiple C2 and transmembrane domain-containing protein 1,GO:0005509; GO:0019722; GO:0016021,calcium ion binding; calcium-mediated signaling; integral to membrane,PF00168;PF08372;,3.00E-28,CHOYP_LOC100900285.1.1,,,,,,,MCTP1_HUMAN,Homo sapiens (Human),calcium-mediated signaling [GO:0019722] comp154411_c0_seq1,302,48.0132,0.43162866,11,0,,2.00E-07,Q96JM4,Leucine-rich repeat and IQ domain-containing protein 1,Leucine-rich repeat and IQ domain-containing protein 1,,,PF00612;,,,,,,,,,LRIQ1_HUMAN,Homo sapiens (Human), comp154412_c0_seq1,238,49.5798,0.41626279,7,0,,2.00E-17,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,2.00E-17,CHOYP_NEMVEDRAFT_V1G239043.2.6,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp154418_c0_seq1,350,47.7143,1.08143488,8,3,,8.00E-50,Q03146,Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a),Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a),GO:0005524; GO:0060444; GO:0005518; GO:0043583; GO:0007566; GO:0016021; GO:0007595; GO:0060749; GO:0046872; GO:0008285; GO:0038083; GO:0005886; GO:0038062; GO:0001558; GO:0001952; GO:0010715; GO:0014909; GO:0061302; GO:0044319,"ATP binding; branching involved in mammary gland duct morphogenesis; collagen binding; ear development; embryo implantation; integral to membrane; lactation; mammary gland alveolus development; metal ion binding; negative regulation of cell proliferation; peptidyl-tyrosine autophosphorylation; plasma membrane; protein tyrosine kinase collagen receptor activity; regulation of cell growth; regulation of cell-matrix adhesion; regulation of extracellular matrix disassembly; smooth muscle cell migration; smooth muscle cell-matrix adhesion; wound healing, spreading of cells",PF00754;PF07714;,5.00E-59,CHOYP_BRAFLDRAFT_225535.1.1,,,,,,,DDR1_MOUSE,Mus musculus (Mouse),"axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell proliferation [GO:0008285]; neuron projection extension [GO:1990138]; organ regeneration [GO:0031100]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; skin development [GO:0043588]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; wound healing, spreading of cells [GO:0044319]" comp154437_c0_seq1,337,45.6973,1.08480685,6,5,,1.00E-12,Q8MJ08,Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor),Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor),GO:0007188; GO:0016021; GO:2000420; GO:0050728; GO:0033624; GO:0005886; GO:0004957,adenylate cyclase-modulating G-protein coupled receptor signaling pathway; integral to membrane; negative regulation of eosinophil extravasation; negative regulation of inflammatory response; negative regulation of integrin activation; plasma membrane; prostaglandin E receptor activity,PF00001;,,,,,,,,,PE2R4_BOVIN,Bos taurus (Bovine),adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cellular response to prostaglandin E stimulus [GO:0071380]; inflammatory response [GO:0006954]; negative regulation of eosinophil extravasation [GO:2000420]; negative regulation of inflammatory response [GO:0050728]; negative regulation of integrin activation [GO:0033624]; positive regulation of cytosolic calcium ion concentration [GO:0007204] comp154447_c0_seq1,288,49.3056,0.77544795,11,0,,7.00E-19,O08762,Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12),GO:0031410; GO:0030425; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252; GO:0043083; GO:0043195; GO:0031638,cytoplasmic vesicle; dendrite; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity; synaptic cleft; terminal bouton; zymogen activation,PF00051;PF00530;PF00089;,4.00E-14,CHOYP_CO6A3.3.5,,,,,,,NETR_MOUSE,Mus musculus (Mouse),exocytosis [GO:0006887]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] comp154454_c0_seq1,263,34.981,0.75179065,8,0,,2.00E-13,Q18779,UDP-sugar transporter sqv-7 (Squashed vulva protein 7),UDP-sugar transporter sqv-7 (Squashed vulva protein 7),GO:0000139; GO:0008643; GO:0005737; GO:0009792; GO:0016021; GO:0002009; GO:0018991; GO:0040025,Golgi membrane; carbohydrate transport; cytoplasm; embryo development ending in birth or egg hatching; integral to membrane; morphogenesis of an epithelium; oviposition; vulval development,PF03151;,,,,,,,,,SQV7_CAEEL,Caenorhabditis elegans,embryo development ending in birth or egg hatching [GO:0009792]; morphogenesis of an epithelium [GO:0002009]; oviposition [GO:0018991]; reproduction [GO:0000003]; UDP-galactose transmembrane transport [GO:0072334]; UDP-glucuronic acid transport [GO:0015787]; UDP-N-acetylgalactosamine transport [GO:0015789]; vulval development [GO:0040025] comp154460_c0_seq1,239,41.0042,0.80268964,7,0,,2.00E-12,O13134,Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4),Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4),GO:0016323; GO:0005452; GO:0016021; GO:0006814; GO:0015293,basolateral plasma membrane; inorganic anion exchanger activity; integral to membrane; sodium ion transport; symporter activity,PF07565;PF00955;,,,,,,,,,S4A4_AMBTI,Ambystoma tigrinum (Eastern tiger salamander),sodium ion transport [GO:0006814] comp154474_c0_seq1,237,40.9283,0.30909641,7,0,,6.00E-28,Q5SQM0,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,2.00E-23,CHOYP_EMAL6.1.1,,,,,,,EMAL6_MOUSE,Mus musculus (Mouse), comp154481_c0_seq1,367,43.5967,0.43229051,3,0,,7.00E-14,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,,,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp154505_c0_seq1,297,66.33,1.11403132,5,0,,2.00E-45,D4H9Y2,Biotin biosynthesis bifunctional protein BioWF [Includes: 6-carboxyhexanoate--CoA ligase (EC 6.2.1.14) (Pimeloyl-CoA synthase); 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (8-amino-7-ketopelargonate synthase)],Biotin biosynthesis bifunctional protein BioWF [Includes: 6-carboxyhexanoate--CoA ligase (EC 6.2.1.14) (Pimeloyl-CoA synthase); 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (8-amino-7-ketopelargonate synthase)],GO:0042410; GO:0008710; GO:0005524; GO:0009102; GO:0030170,6-carboxyhexanoate-CoA ligase activity; 8-amino-7-oxononanoate synthase activity; ATP binding; biotin biosynthetic process; pyridoxal phosphate binding,PF00155;PF03744;,,,,,,,,,BIOWF_PROAS,Propionibacterium acnes (strain SK137),biotin biosynthetic process [GO:0009102] comp154506_c0_seq1,232,43.9655,0.46976679,7,0,,,,,,,,,,,6.00E-28,ruditapes_c26495,,,,,,, comp154513_c0_seq1,265,41.1321,0.80770381,7,1,,2.00E-12,Q13075,Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein),GO:0005524; GO:0016323; GO:0004869; GO:0005737; GO:0006954; GO:0045087; GO:0046872; GO:0043154; GO:0043524; GO:0007399; GO:0017111,ATP binding; basolateral plasma membrane; cysteine-type endopeptidase inhibitor activity; cytoplasm; inflammatory response; innate immune response; metal ion binding; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of neuron apoptotic process; nervous system development; nucleoside-triphosphatase activity,PF00653;,,,,,,,,,BIRC1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678] comp154517_c0_seq1,279,62.3656,1.15059803,1,7,,8.00E-09,A1VJ23,Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK),Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK),GO:0005524; GO:0019563; GO:0004370; GO:0006071; GO:0006072,ATP binding; glycerol catabolic process; glycerol kinase activity; glycerol metabolic process; glycerol-3-phosphate metabolic process,PF02782;PF00370;,,,,,,,,,GLPK_POLNA,Polaromonas naphthalenivorans (strain CJ2),glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071] comp154519_c0_seq1,403,46.402,0.41621135,13,0,,8.00E-17,Q6DIR8,Paladin,Paladin,GO:0005829,cytosol,,,,,,,,,,PALD_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp154528_c0_seq1,317,47.9495,0.3303357,6,0,,2.00E-36,Q7PHR1,Kinesin-like protein unc-104,Kinesin-like protein unc-104,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0005875; GO:0003777; GO:0005543; GO:0048489; GO:0047496,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule associated complex; microtubule motor activity; phospholipid binding; synaptic vesicle transport; vesicle transport along microtubule,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,2.00E-63,CHOYP_LOC100875479.2.2,,,,,,,KIF1A_ANOGA,Anopheles gambiae (African malaria mosquito),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] comp154529_c0_seq1,375,36.2667,1.43480257,9,0,,,,,,,,,,,5.00E-13,ruditapes_c31994,,,,,,, comp154547_c0_seq1,226,43.3628,0.75921219,3,0,,4.00E-10,Q8VHY0,Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2),Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2),GO:0000187; GO:0001525; GO:0016324; GO:0008283; GO:0008347; GO:0016021; GO:0035556; GO:0031258; GO:0005886; GO:0050731; GO:0004871; GO:0048771; GO:0007169,activation of MAPK activity; angiogenesis; apical plasma membrane; cell proliferation; glial cell migration; integral to membrane; intracellular signal transduction; lamellipodium membrane; plasma membrane; positive regulation of peptidyl-tyrosine phosphorylation; signal transducer activity; tissue remodeling; transmembrane receptor protein tyrosine kinase signaling pathway,PF00054;PF02210;,,,,,,,,,CSPG4_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; cell proliferation [GO:0008283]; glial cell migration [GO:0008347]; intracellular signal transduction [GO:0035556]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; tissue remodeling [GO:0048771]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp154551_c0_seq1,352,36.9318,0.41815073,3,6,,5.00E-16,Q58D05,TRAF-type zinc finger domain-containing protein 1,TRAF-type zinc finger domain-containing protein 1,GO:0046872; GO:0045824,metal ion binding; negative regulation of innate immune response,,4.00E-29,CHOYP_LOC100368148.1.1,,,,,,,TRAD1_BOVIN,Bos taurus (Bovine),negative regulation of innate immune response [GO:0045824] comp154557_c0_seq1,223,59.6413,0.75985246,4,1,,8.00E-09,P39045,D-alanyl-D-alanine carboxypeptidase (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein) (PBP),D-alanyl-D-alanine carboxypeptidase (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein) (PBP),GO:0005576; GO:0009252; GO:0006508; GO:0008360; GO:0046677; GO:0009002,extracellular region; peptidoglycan biosynthetic process; proteolysis; regulation of cell shape; response to antibiotic; serine-type D-Ala-D-Ala carboxypeptidase activity,PF02113;,,,,,,,,,DAC_ACTSP,Actinomadura sp. (strain R39),cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677] comp154577_c0_seq1,203,44.8276,0,4,0,,,,,,,,,2.00E-23,CHOYP_UBR3.1.1,,,,,,,,, comp154590_c0_seq1,240,72.9167,1.29572142,0,9,,5.00E-08,P28811,3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31),3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31),GO:0008442; GO:0051287; GO:0004365; GO:0006550; GO:0006552; GO:0006098; GO:0004616; GO:0006574,3-hydroxyisobutyrate dehydrogenase activity; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; isoleucine catabolic process; leucine catabolic process; pentose-phosphate shunt; phosphogluconate dehydrogenase (decarboxylating) activity; valine catabolic process,PF14833;PF03446;,,,,,,,,,MMSB_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),valine catabolic process [GO:0006574] comp154592_c0_seq1,224,62.5,1.15174286,0,8,,1.00E-13,O31427,SkfA peptide export ATP-binding protein SkfE (EC 3.6.3.25),SkfA peptide export ATP-binding protein SkfE (EC 3.6.3.25),GO:0005524; GO:0006200; GO:0005886; GO:0015419,ATP binding; ATP catabolic process; plasma membrane; sulfate transmembrane-transporting ATPase activity,PF00005;,,,,,,,,,SKFE_BACSU,Bacillus subtilis (strain 168),bacteriocin biosynthetic process [GO:0030152] comp154599_c0_seq1,275,45.4545,0.8725089,10,0,,5.00E-47,Q5REC2,Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (Prohormone convertase 2) (Proprotein convertase 2) (PC2),Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (Prohormone convertase 2) (Proprotein convertase 2) (PC2),GO:0034230; GO:0005615; GO:0030070; GO:0016020; GO:0007399; GO:0016540; GO:0006508; GO:0004252; GO:0030133,enkephalin processing; extracellular space; insulin processing; membrane; nervous system development; protein autoprocessing; proteolysis; serine-type endopeptidase activity; transport vesicle,PF01483;PF00082;PF16470;,8.00E-49,CHOYP_PC2.2.2,,,,,,,NEC2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),enkephalin processing [GO:0034230]; insulin processing [GO:0030070]; nervous system development [GO:0007399]; protein autoprocessing [GO:0016540] comp154620_c0_seq1,213,53.5211,0.39827181,7,0,,1.00E-41,Q7QBX2,40S ribosomal protein S14b,40S ribosomal protein S14b,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00411;,2.00E-80,CHOYP_RS14.5.6,3.00E-50,ruditapes2_lrc4878,,,,,RS14B_ANOGA,Anopheles gambiae (African malaria mosquito),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]" comp154621_c0_seq1,258,44.186,0.41124784,8,0,,8.00E-11,Q6UR05,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,7.00E-30,CHOYP_MRP1.5.10,,,,,,,MRP1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp154627_c0_seq1,413,49.3947,0.68465518,11,2,,,,,,,,,1.00E-11,CHOYP_BRAFLDRAFT_63676.1.1,4.00E-21,ruditapes_c14548,,,,,,, comp154633_c0_seq1,223,43.0493,0.78084359,7,0,,5.00E-14,P23978,Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1),Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1),GO:0030424; GO:0009986; GO:0051939; GO:0005332; GO:0005887; GO:0007612; GO:0032229; GO:0043005; GO:0005328; GO:0005886; GO:0014054; GO:0051260; GO:0051592; GO:0042220; GO:0032355; GO:0010288; GO:0014074; GO:0009744; GO:0009636,"axon; cell surface; gamma-aminobutyric acid import; gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; learning; negative regulation of synaptic transmission, GABAergic; neuron projection; neurotransmitter:sodium symporter activity; plasma membrane; positive regulation of gamma-aminobutyric acid secretion; protein homooligomerization; response to calcium ion; response to cocaine; response to estradiol stimulus; response to lead ion; response to purine-containing compound; response to sucrose stimulus; response to toxic substance",PF00209;,,,,,,,,,SC6A1_RAT,Rattus norvegicus (Rat),"gamma-aminobutyric acid import [GO:0051939]; learning [GO:0007612]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neurotransmitter transport [GO:0006836]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; protein homooligomerization [GO:0051260]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]" comp154656_c0_seq1,218,40.8257,0.93691811,2,7,,2.00E-11,P17128,Actin,Actin,GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,,,,,,,,,ACT_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),actomyosin contractile ring contraction [GO:0000916]; ascospore wall assembly [GO:0030476]; cellular response to oxidative stress [GO:0034599]; chronological cell aging [GO:0001300]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; mitotic actomyosin contractile ring assembly [GO:1903475]; protein secretion [GO:0009306]; regulation of endocytosis [GO:0030100]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; vacuole inheritance [GO:0000011] comp154662_c0_seq1,206,63.1068,1.13359814,4,1,,2.00E-12,B2VJR7,Glycogen debranching enzyme (EC 3.2.1.-) (Glycogen operon protein GlgX),Glycogen debranching enzyme (EC 3.2.1.-) (Glycogen operon protein GlgX),GO:0043169; GO:0005980; GO:0004133; GO:0004553,"cation binding; glycogen catabolic process; glycogen debranching enzyme activity; hydrolase activity, hydrolyzing O-glycosyl compounds",PF00128;PF02922;,,,,,,,,,GLGX_ERWT9,Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99),glycogen catabolic process [GO:0005980] comp154682_c0_seq1,233,61.3734,0.88886083,0,6,,8.00E-07,Q10817,Uncharacterized protein Rv2896c/MT2964,,GO:0009294,DNA mediated transformation,,,,,,,,,,Y2896_MYCTU,, comp154700_c0_seq1,667,43.928,0.39542315,18,2,,1.00E-15,A6NDV4,Transmembrane protein 8B (Nasopharyngeal carcinoma-associated gene 6 protein) (Protein NAG-5) (Protein NGX6),Transmembrane protein 8B (Nasopharyngeal carcinoma-associated gene 6 protein) (Protein NAG-5) (Protein NGX6),GO:0009986; GO:0007160; GO:0005783; GO:0016021; GO:0005739; GO:0005634; GO:0005886; GO:0040008; GO:0007346,cell surface; cell-matrix adhesion; endoplasmic reticulum; integral to membrane; mitochondrion; nucleus; plasma membrane; regulation of growth; regulation of mitotic cell cycle,PF12036;,,,,,,,,,TMM8B_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346] comp154714_c0_seq1,531,46.7043,0.51929643,12,0,,6.00E-25,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp154725_c0_seq1,352,40.625,0.69461403,9,1,,4.00E-10,Q498W5,Transmembrane protein 198-B,Transmembrane protein 198-B,GO:0016021,integral to membrane,PF13886;,,,,,,,,,T198B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp154740_c0_seq1,355,43.662,0.88911794,8,0,,9.00E-38,P12822,"Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]","Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]",GO:0004180; GO:0005576; GO:0016021; GO:0046872; GO:0008237; GO:0008241; GO:0005886; GO:0006508,carboxypeptidase activity; extracellular region; integral to membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; plasma membrane; proteolysis,PF01401;,1.00E-28,CHOYP_ACE.1.4,,,,,,,ACE_RABIT,Oryctolagus cuniculus (Rabbit), comp154746_c0_seq1,226,43.8053,0.5605048,6,0,,3.00E-34,Q5R7A4,Ras-related protein Rab-7L1 (Rab-7-like protein 1),Ras-related protein Rab-7L1 (Rab-7-like protein 1),GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,1.00E-45,CHOYP_PHUM_PHUM310360.1.1,,,,,,,RAB7L_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; negative regulation of neuron projection development [GO:0010977]; positive regulation of intracellular protein transport [GO:0090316]; protein transport [GO:0015031]; retrograde transport, plasma membrane to Golgi [GO:0035526]; small GTPase mediated signal transduction [GO:0007264]" comp154747_c0_seq1,213,46.0094,1.18017307,2,3,,4.00E-11,Q5VV43,Dyslexia-associated protein KIAA0319,Dyslexia-associated protein KIAA0319,GO:0005769; GO:0031901; GO:0016021; GO:2000171; GO:0001764; GO:0005886,early endosome; early endosome membrane; integral to membrane; negative regulation of dendrite development; neuron migration; plasma membrane,PF02010;,,,,,,,,,K0319_HUMAN,Homo sapiens (Human),negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764] comp154754_c0_seq1,227,35.2423,0.29400957,2,6,,2.00E-19,O15156,Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK),Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK),GO:0003677; GO:0030154; GO:0007398; GO:0046872; GO:0007275; GO:0005634; GO:0045944; GO:0043370; GO:0043376; GO:0003700; GO:0006366,"DNA binding; cell differentiation; ectoderm development; metal ion binding; multicellular organismal development; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of CD4-positive, alpha-beta T cell differentiation; regulation of CD8-positive, alpha-beta T cell differentiation; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter",PF00651;,,,,,,,,,ZBT7B_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; multicellular organism development [GO:0007275]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp154757_c0_seq1,211,47.8673,0.35422684,4,3,,3.00E-07,Q53HC5,Kelch-like protein 26,Kelch-like protein 26,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH26_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp154758_c0_seq1,220,69.5455,0.96592905,0,8,,3.00E-31,A9BNJ5,Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III),Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III),GO:0005737; GO:0006397; GO:0046872; GO:0090305; GO:0019843; GO:0016075; GO:0006364; GO:0004525; GO:0008033,cytoplasm; mRNA processing; metal ion binding; nucleic acid phosphodiester bond hydrolysis; rRNA binding; rRNA catabolic process; rRNA processing; ribonuclease III activity; tRNA processing,PF00035;PF14622;,,,,,,,,,RNC_DELAS,Delftia acidovorans (strain DSM 14801 / SPH-1),mRNA processing [GO:0006397]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033] comp154760_c0_seq1,201,55.7214,1.29200512,0,4,,4.00E-32,Q6A7M5,Translation initiation factor IF-2,Translation initiation factor IF-2,GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation initiation factor activity,PF11987;PF04760;,,,,,,,,,IF2_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp154781_c0_seq1,333,45.045,0.47511097,7,0,,5.00E-12,Q9V4A7,Plexin-B,Plexin-B,GO:0016021; GO:0005622; GO:0008045; GO:0035021; GO:0005886; GO:0035025; GO:0004872; GO:0007165,integral to membrane; intracellular; motor neuron axon guidance; negative regulation of Rac protein signal transduction; plasma membrane; positive regulation of Rho protein signal transduction; receptor activity; signal transduction,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; negative regulation of Rac protein signal transduction [GO:0035021]; olfactory bulb axon guidance [GO:0071678]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374] comp154784_c0_seq1,275,42.1818,0.75663504,9,0,,4.00E-23,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp154798_c0_seq1,221,42.5339,1.06324016,3,4,,1.00E-12,P54282,"Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide, isoform 4) (Rat brain class A) (RBA-I) (Voltage-gated calcium channel subunit alpha Cav2.1)","Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide, isoform 4) (Rat brain class A) (RBA-I) (Voltage-gated calcium channel subunit alpha Cav2.1)",GO:0070509; GO:0005516; GO:0007204; GO:0008331; GO:0046872; GO:0043204; GO:0019233; GO:0007268; GO:0005891,calcium ion import; calmodulin binding; elevation of cytosolic calcium ion concentration; high voltage-gated calcium channel activity; metal ion binding; perikaryon; sensory perception of pain; synaptic transmission; voltage-gated calcium channel complex,PF08763;PF16905;PF00520;,7.00E-29,CHOYP_LOC100647135.2.2,,,,,,,CAC1A_RAT,Rattus norvegicus (Rat),calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; membrane depolarization during action potential [GO:0086010]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; sensory perception of pain [GO:0019233] comp154804_c0_seq1,206,48.5437,1.49103153,0,4,,3.00E-07,P03737,Minor tail protein M,Tail tip protein M,,,PF05939;,,,,,,,,,VMTM_LAMBD,Enterobacteria phage lambda (Bacteriophage lambda),viral release from host cell [GO:0019076] comp154817_c0_seq1,217,44.7005,0.4646305,4,1,,3.00E-28,Q80U56,Late secretory pathway protein AVL9 homolog,Late secretory pathway protein AVL9 homolog,GO:0016477; GO:0016021; GO:0055037,cell migration; integral to membrane; recycling endosome,PF09794;,7.00E-23,CHOYP_LOC591009.1.1,,,,,,,AVL9_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477] comp154825_c0_seq1,293,38.9078,0.36240792,0,8,,2.00E-26,Q3UDW8,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0016746,"heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; transferase activity, transferring acyl groups",PF07786;,,,,,,,,,HGNAT_MOUSE,Mus musculus (Mouse),lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp154831_c0_seq1,310,46.129,0.91795524,8,0,,2.00E-18,Q6P9Z4,Protein fem-1 homolog A (FEM1a) (FEM1-alpha),Protein fem-1 homolog A (FEM1a) (FEM1-alpha),GO:0005737; GO:0051438; GO:0004842,cytoplasm; regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,PF12796;,,,,,,,,,FEM1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of ubiquitin-protein transferase activity [GO:0051438] comp154859_c0_seq1,293,43.0034,1.00580119,11,0,,2.00E-20,Q9QZ85,Interferon-inducible GTPase 1 (EC 3.6.5.-),Interferon-inducible GTPase 1 (EC 3.6.5.-),GO:0019003; GO:0005525; GO:0003924; GO:0032580; GO:0035458; GO:0019221; GO:0050829; GO:0042832; GO:0005789; GO:0042802; GO:0045087; GO:0031965; GO:0010506; GO:0020005,GDP binding; GTP binding; GTPase activity; Golgi cisterna membrane; cellular response to interferon-beta; cytokine-mediated signaling pathway; defense response to Gram-negative bacterium; defense response to protozoan; endoplasmic reticulum membrane; identical protein binding; innate immune response; nuclear membrane; regulation of autophagy; symbiont-containing vacuole membrane,PF05049;,,,,,,,,,IIGP1_MOUSE,Mus musculus (Mouse),cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506] comp154861_c0_seq1,258,43.7984,0.66796619,8,1,,5.00E-14,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp154877_c0_seq1,222,40.5405,0.77432127,5,0,,,,,,,,,,,3.00E-12,ruditapes2_c3049,,,,,,, comp154883_c0_seq1,282,43.617,0.39024208,1,6,,9.00E-25,Q9VUX2,E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib),E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib),GO:0007219; GO:0045179; GO:0005829; GO:0006897; GO:0046331; GO:0045747; GO:0008104; GO:0007423; GO:0004842; GO:0008270,Notch signaling pathway; apical cortex; cytosol; endocytosis; lateral inhibition; positive regulation of Notch signaling pathway; protein localization; sensory organ development; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB_DROME,Drosophila melanogaster (Fruit fly),compound eye development [GO:0048749]; endocytosis [GO:0006897]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of Notch signaling pathway [GO:0008593]; sensory organ development [GO:0007423] comp154915_c0_seq1,241,35.2697,0.9442749,6,0,,4.00E-08,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp154924_c0_seq1,264,42.803,0.93430828,7,0,,7.00E-33,P79098,Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,6.00E-31,CHOYP_LOC409619.4.4,,,,,,,AMPN_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp154943_c0_seq1,248,39.9194,1.22561468,7,1,,1.00E-13,Q811X6,Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),GO:0003857; GO:0050104; GO:0070403; GO:0005829; GO:0006631,3-hydroxyacyl-CoA dehydrogenase activity; L-gulonate 3-dehydrogenase activity; NAD+ binding; cytosol; fatty acid metabolic process,PF00725;PF02737;,,,,,,,,,CRYL1_RAT,Rattus norvegicus (Rat),fatty acid metabolic process [GO:0006631] comp154973_c0_seq1,221,43.4389,0.78308482,7,0,,6.00E-13,P35382,5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) (Fragment),5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) (Fragment),GO:0030424; GO:0007610; GO:0005901; GO:0016023; GO:0043198; GO:0005887; GO:0050795; GO:0046883; GO:0004993; GO:0007210; GO:0006939,axon; behavior; caveola; cytoplasmic membrane-bounded vesicle; dendritic shaft; integral to plasma membrane; regulation of behavior; regulation of hormone secretion; serotonin receptor activity; serotonin receptor signaling pathway; smooth muscle contraction,PF00001;,,,,,,,,,5HT2A_CAVPO,Cavia porcellus (Guinea pig),behavior [GO:0007610]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; smooth muscle contraction [GO:0006939] comp154976_c0_seq1,282,46.8085,0.65937455,6,0,,4.00E-13,P98164,Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008283; GO:0005905; GO:0030139; GO:0005783; GO:0005768; GO:0030900; GO:0016021; GO:0005765; GO:0007603; GO:0006486; GO:0006898; GO:0001523; GO:0042359,"Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cell proliferation; coated pit; endocytic vesicle; endoplasmic reticulum; endosome; forebrain development; integral to membrane; lysosomal membrane; phototransduction, visible light; protein glycosylation; receptor-mediated endocytosis; retinoid metabolic process; vitamin D metabolic process",PF12662;PF07645;PF00057;PF00058;,,,,,,,,,LRP2_HUMAN,Homo sapiens (Human),aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; endocytosis [GO:0006897]; forebrain development [GO:0030900]; lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486]; receptor-mediated endocytosis [GO:0006898]; retinoid metabolic process [GO:0001523]; ventricular septum development [GO:0003281]; vitamin D metabolic process [GO:0042359] comp154994_c0_seq1,334,44.9102,1.20158896,4,4,,1.00E-47,O95436,Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2),Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2),GO:0007568; GO:0016324; GO:0031526; GO:0030643; GO:0001701; GO:0005887; GO:0042301; GO:0032355; GO:0043627; GO:0009750; GO:0031402; GO:0015321; GO:0005436,aging; apical plasma membrane; brush border membrane; cellular phosphate ion homeostasis; in utero embryonic development; integral to plasma membrane; phosphate ion binding; response to estradiol stimulus; response to estrogen stimulus; response to fructose stimulus; sodium ion binding; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity,PF02690;,,,,,,,,,NPT2B_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; cellular protein metabolic process [GO:0044267]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estrogen [GO:0043627] comp154995_c0_seq1,270,46.6667,0.82960322,5,0,,5.00E-25,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,8.00E-15,ruditapes2_c1330,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp154998_c0_seq1,290,34.8276,1.25826968,2,6,,2.00E-08,Q8TC21,Zinc finger protein 596,Zinc finger protein 596,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN596_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp155042_c0_seq1,348,46.2644,0.54209829,6,1,,7.00E-15,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp155048_c0_seq1,259,48.2625,0.4160062,4,0,,,,,,,,,3.00E-22,CHOYP_MATN1.3.5,,,,,,,,, comp155060_c0_seq1,258,40.6977,0.28949764,4,2,,9.00E-28,Q96DM3,Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1),Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1),GO:0005765,lysosomal membrane,PF07035;,9.00E-35,CHOYP_BRAFLDRAFT_87849.1.1,,,,,,,MIC1_HUMAN,Homo sapiens (Human), comp155063_c0_seq1,238,45.7983,0.24239779,6,0,,2.00E-13,Q55EH8,ABC transporter G family member 23 (ABC transporter ABCG.23),ABC transporter G family member 23 (ABC transporter ABCG.23),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF00005;,1.00E-27,CHOYP_LOC101072538.1.1,,,,,,,ABCGN_DICDI,Dictyostelium discoideum (Slime mold),transport [GO:0006810] comp155068_c0_seq1,214,36.9159,0.27922688,7,0,,,,,,,,,4.00E-26,CHOYP_BM1_14460.1.1,,,,,,,,, comp155086_c0_seq1,212,43.3962,0.80683613,2,6,,,,,,,,,,,6.00E-15,ruditapes_c18410,,,,,,, comp155121_c0_seq1,223,36.7713,0.9378179,2,5,,1.00E-10,A5PJU6,Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1),Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1),GO:0005737; GO:0047992,cytoplasm; hydroxylysine kinase activity,PF01636;,,,,,,,,,AGPD1_BOVIN,Bos taurus (Bovine), comp155130_c0_seq1,240,43.75,0.66261952,5,0,,7.00E-11,P31228,D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),GO:0003884; GO:0008445; GO:0005777,D-amino-acid oxidase activity; D-aspartate oxidase activity; peroxisome,PF01266;,,,,,,,,,OXDD_BOVIN,Bos taurus (Bovine),D-amino acid metabolic process [GO:0046416] comp155141_c0_seq1,201,47.7612,0.26348478,6,0,,9.00E-07,Q9VAC5,ADAM 17-like protease (EC 3.4.24.-),ADAM 17-like protease (EC 3.4.24.-),GO:0016021; GO:0006509; GO:0004222; GO:0008270,integral to membrane; membrane protein ectodomain proteolysis; metalloendopeptidase activity; zinc ion binding,PF16698;PF00200;PF01562;,,,,,,,,,ADA17_DROME,Drosophila melanogaster (Fruit fly),membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] comp155152_c0_seq1,217,43.318,0.31671375,3,2,,1.00E-16,Q90744,Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B),Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B),GO:0008456; GO:0005975; GO:0005764,alpha-N-acetylgalactosaminidase activity; carbohydrate metabolic process; lysosome,PF16499;,,,,,,,,,NAGAB_CHICK,Gallus gallus (Chicken),carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139] comp155156_c0_seq1,206,42.233,0.32823184,4,3,,2.00E-23,Q96JK2,DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22),DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22),GO:0080008; GO:0005739; GO:0016567,Cul4-RING ubiquitin ligase complex; mitochondrion; protein ubiquitination,PF00400;,2.00E-17,CHOYP_DCAF5.1.1,,,,,,,DCAF5_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp155161_c0_seq1,271,41.3284,0.26322939,7,0,,2.00E-17,Q5T447,E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),GO:0005634; GO:0048471; GO:0043161; GO:0042787; GO:0004842,nucleus; perinuclear region of cytoplasm; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF03256;PF00632;,3.00E-16,CHOYP_BRAFLDRAFT_276868.1.1,,,,,,,HECD3_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp155172_c0_seq1,204,60.7843,1.08468215,2,4,,8.00E-12,A1TA72,GTPase Der (GTP-binding protein EngA),GTPase Der (GTP-binding protein EngA),GO:0005525; GO:0017111; GO:0042254,GTP binding; nucleoside-triphosphatase activity; ribosome biogenesis,PF14714;PF01926;,,,,,,,,,DER_MYCVP,Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1),ribosome biogenesis [GO:0042254] comp155178_c0_seq1,218,43.578,0.97162648,3,3,,4.00E-10,Q9H251,Cadherin-23 (Otocadherin),Cadherin-23 (Otocadherin),GO:0005509; GO:0006816; GO:0016339; GO:0051480; GO:0050957; GO:0007156; GO:0016021; GO:0016020; GO:0045494; GO:0005886; GO:0050896; GO:0050953; GO:0007605; GO:0032420; GO:0007601,calcium ion binding; calcium ion transport; calcium-dependent cell-cell adhesion; cytosolic calcium ion homeostasis; equilibrioception; homophilic cell adhesion; integral to membrane; membrane; photoreceptor cell maintenance; plasma membrane; response to stimulus; sensory perception of light stimulus; sensory perception of sound; stereocilium; visual perception,PF00028;,,,,,,,,,CAD23_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp155189_c0_seq1,252,40.873,0.38189281,7,3,,8.00E-06,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp155192_c0_seq1,217,44.2396,0.47640872,4,1,,1.00E-26,Q03468,DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),GO:0005524; GO:0003677; GO:0008094; GO:0007256; GO:0007257; GO:0006284; GO:0003682; GO:0004386; GO:0008630; GO:0035264; GO:0005730; GO:0045494; GO:0032786; GO:0032403; GO:0006290; GO:0009411; GO:0010224; GO:0010165; GO:0010332; GO:0006979; GO:0000303; GO:0009636; GO:0008023; GO:0006366; GO:0006283,"ATP binding; DNA binding; DNA-dependent ATPase activity; activation of JNKK activity; activation of JUN kinase activity; base-excision repair; chromatin binding; helicase activity; intrinsic apoptotic signaling pathway in response to DNA damage; multicellular organism growth; nucleolus; photoreceptor cell maintenance; positive regulation of DNA-dependent transcription, elongation; protein complex binding; pyrimidine dimer repair; response to UV; response to UV-B; response to X-ray; response to gamma radiation; response to oxidative stress; response to superoxide; response to toxic substance; transcription elongation factor complex; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF00271;PF00176;,,,,,,,,,ERCC6_HUMAN,Homo sapiens (Human),"activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]" comp155226_c0_seq1,210,49.5238,0.62450547,5,1,,5.00E-25,Q16827,Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2),Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2),GO:0017147; GO:0016324; GO:0030424; GO:0007411; GO:0043197; GO:0072112; GO:0030426; GO:0005887; GO:0030027; GO:0030032; GO:0016328; GO:0002548; GO:0090090; GO:0010812; GO:0003105; GO:0010977; GO:0090260; GO:0042803; GO:0036060; GO:0005001,Wnt-protein binding; apical plasma membrane; axon; axon guidance; dendritic spine; glomerular visceral epithelial cell differentiation; growth cone; integral to plasma membrane; lamellipodium; lamellipodium assembly; lateral plasma membrane; monocyte chemotaxis; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cell-substrate adhesion; negative regulation of glomerular filtration; negative regulation of neuron projection development; negative regulation of retinal ganglion cell axon guidance; protein homodimerization activity; slit diaphragm assembly; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF00102;,2.00E-16,CHOYP_PHUM_PHUM530510.1.1,,,,,,,PTPRO_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; glomerular visceral epithelial cell differentiation [GO:0072112]; glomerulus development [GO:0032835]; lamellipodium assembly [GO:0030032]; monocyte chemotaxis [GO:0002548]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of glomerular filtration [GO:0003105]; negative regulation of neuron projection development [GO:0010977]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of glomerular filtration [GO:0003093]; slit diaphragm assembly [GO:0036060] comp155228_c0_seq1,307,43.3225,0.49089774,9,0,,1.00E-18,O05218,Putative gamma-glutamyltransferase YwrD (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain],Putative gamma-glutamyltransferase YwrD (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain],GO:0003840; GO:0036374; GO:0006749,gamma-glutamyltransferase activity; glutathione hydrolase activity; glutathione metabolic process,PF01019;,8.00E-24,CHOYP_NEMVEDRAFT_V1G169538.1.2,,,,,,,YWRD_BACSU,Bacillus subtilis (strain 168),glutathione metabolic process [GO:0006749] comp155252_c0_seq1,232,42.6724,0.38041523,5,3,,6.00E-19,A5PKJ4,Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24),Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24),GO:0005524; GO:0004707; GO:0000165; GO:0016605; GO:0006915; GO:0007049; GO:0030154; GO:0070301; GO:0071560; GO:0005737; GO:0005829; GO:0051534; GO:2000352; GO:2001240; GO:0034115; GO:1902176; GO:0060761; GO:0018105; GO:0051247; GO:0036003; GO:0045765,ATP binding; MAP kinase activity; MAPK cascade; PML body; apoptotic process; cell cycle; cell differentiation; cellular response to hydrogen peroxide; cellular response to transforming growth factor beta stimulus; cytoplasm; cytosol; negative regulation of NFAT protein import into nucleus; negative regulation of endothelial cell apoptotic process; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of heterotypic cell-cell adhesion; negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of response to cytokine stimulus; peptidyl-serine phosphorylation; positive regulation of protein metabolic process; positive regulation of transcription from RNA polymerase II promoter in response to stress; regulation of angiogenesis,PF00069;,,,,,,,,,MK07_BOVIN,Bos taurus (Bovine),cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK5 cascade [GO:0070377]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of angiogenesis [GO:0045765] comp155256_c0_seq1,220,46.3636,1.10502283,2,4,,,,,,,,,,,3.00E-19,ruditapes_c26839,,,,,,, comp155259_c0_seq1,329,44.3769,0.37155532,5,3,,4.00E-22,O00750,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta),Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta),GO:0016303; GO:0035005; GO:0005524; GO:0030139; GO:0005783; GO:0043231; GO:0001727; GO:0005634; GO:0005942; GO:0035091; GO:0048015; GO:0005886; GO:0043491; GO:0044281,1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; endocytic vesicle; endoplasmic reticulum; intracellular membrane-bounded organelle; lipid kinase activity; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol binding; phosphatidylinositol-mediated signaling; plasma membrane; protein kinase B signaling cascade; small molecule metabolic process,PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;,2.00E-19,CHOYP_LOC100121969.1.1,,,,,,,P3C2B_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491] comp155272_c0_seq1,216,42.1296,0.6420256,5,0,,4.00E-22,Q86UB9,Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52),Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52),GO:0016021; GO:0005777; GO:0007031,integral to membrane; peroxisome; peroxisome organization,PF02466;PF15982;,,,,,,,,,TM135_HUMAN,Homo sapiens (Human),peroxisome organization [GO:0007031] comp155279_c0_seq1,332,41.2651,1.01746886,8,0,,1.00E-29,Q9H772,"Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)","Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)",GO:0030509; GO:0005576; GO:0005615,BMP signaling pathway; extracellular region; extracellular space,PF03045;,,,,,,,,,GREM2_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal identity [GO:0048263]; embryonic body morphogenesis [GO:0010172]; regulation of cytokine activity [GO:0060300]; sequestering of BMP from receptor via BMP binding [GO:0038098] comp155297_c0_seq1,285,43.5088,0.4468805,3,3,,,,,,,,,8.00E-11,CHOYP_LOC658322.1.1,,,,,,,,, comp155347_c0_seq1,204,38.7255,0.66560041,5,0,,4.00E-11,Q5F4C0,Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1),Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1),GO:0016021; GO:0009268; GO:0010043; GO:0030171,integral to membrane; response to pH; response to zinc ion; voltage-gated proton channel activity,PF00520;PF16799;,,,,,,,,,HVCN1_CHICK,Gallus gallus (Chicken),cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transport [GO:0015992]; response to pH [GO:0009268]; response to zinc ion [GO:0010043] comp155372_c0_seq1,304,49.6711,0.85705177,6,0,,3.00E-39,Q7PHR1,Kinesin-like protein unc-104,Kinesin-like protein unc-104,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0005875; GO:0003777; GO:0005543; GO:0048489; GO:0047496,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule associated complex; microtubule motor activity; phospholipid binding; synaptic vesicle transport; vesicle transport along microtubule,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,8.00E-37,CHOYP_LOC100875479.2.2,,,,,,,KIF1A_ANOGA,Anopheles gambiae (African malaria mosquito),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] comp15537_c0_seq1,253,43.083,0.34232341,0,4,,9.00E-06,Q8WNR0,High affinity copper uptake protein 1 (Copper transporter 1) (CTR1) (Solute carrier family 31 member 1),High affinity copper uptake protein 1 (Copper transporter 1) (CTR1) (Solute carrier family 31 member 1),GO:0005375; GO:0016021; GO:0005886,copper ion transmembrane transporter activity; integral to membrane; plasma membrane,PF04145;,,,,,,,,,COPT1_PIG,Sus scrofa (Pig), comp155401_c0_seq1,278,46.0432,0.48104071,7,0,,1.00E-41,O54967,Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2),Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2),GO:0005524; GO:0005912; GO:0030424; GO:0030136; GO:0005905; GO:0030659; GO:0030425; GO:0006897; GO:0005768; GO:0030426; GO:0046872; GO:0043025; GO:0004715; GO:0005634; GO:0018108; GO:0005886; GO:0004674,ATP binding; adherens junction; axon; clathrin-coated vesicle; coated pit; cytoplasmic vesicle membrane; dendrite; endocytosis; endosome; growth cone; metal ion binding; neuronal cell body; non-membrane spanning protein tyrosine kinase activity; nucleus; peptidyl-tyrosine phosphorylation; plasma membrane; protein serine/threonine kinase activity,PF09027;PF11555;PF07714;PF14604;,1.00E-21,CHOYP_TNK2.1.1,,,,,,,ACK1_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; cell migration [GO:0016477]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of clathrin-mediated endocytosis [GO:2000369]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp155442_c0_seq1,507,43.3925,0.41997518,13,0,,1.00E-11,Q4VNC0,Probable cation-transporting ATPase 13A5 (EC 3.6.3.-) (P5-ATPase isoform 5),Probable cation-transporting ATPase 13A5 (EC 3.6.3.-) (P5-ATPase isoform 5),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,,,,,,,,,AT135_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220] comp155446_c0_seq1,348,44.2529,0.41204591,8,0,,2.00E-07,Q9ULD6,Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6),Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6),GO:0009986; GO:0042384; GO:0005737; GO:0060173; GO:0007399; GO:0008589; GO:0021513,cell surface; cilium assembly; cytoplasm; limb development; nervous system development; regulation of smoothened signaling pathway; spinal cord dorsal/ventral patterning,,,,,,,,,,INTU_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; embryonic digit morphogenesis [GO:0042733]; hair follicle morphogenesis [GO:0031069]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile primary cilium assembly [GO:1903887]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; spinal cord dorsal/ventral patterning [GO:0021513] comp155451_c0_seq1,255,46.6667,0.36158748,10,0,,4.00E-10,P32198,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0071398; GO:0042755; GO:0006635; GO:0006006; GO:0042802; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006810; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; cellular response to fatty acid; eating behavior; fatty acid beta-oxidation; glucose metabolic process; identical protein binding; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; transport; triglyceride metabolic process,PF00755;PF16484;,2.00E-11,CHOYP_LOC577934.1.1,,,,,,,CPT1A_RAT,Rattus norvegicus (Rat),carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641] comp155478_c0_seq1,202,46.5347,0.7351923,3,0,,4.00E-31,Q945U1,40S ribosomal protein S15,40S ribosomal protein S15,GO:0003723; GO:0015935; GO:0003735; GO:0006412,RNA binding; small ribosomal subunit; structural constituent of ribosome; translation,PF00203;,2.00E-73,CHOYP_LOC100186361.3.3,3.00E-37,ruditapes2_c4596,,,,,RS15_ELAOL,Elaeis oleifera (American oil palm) (Corozo oleifera),translation [GO:0006412] comp155499_c0_seq1,249,41.7671,0.37481864,5,0,,9.00E-35,Q92562,"Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)","Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)",GO:0000139; GO:0008219; GO:0031901; GO:0031902; GO:0007626; GO:0032288; GO:0031642; GO:0048666; GO:0043813; GO:0004438; GO:0043812; GO:0043473; GO:0010976; GO:0044281; GO:0007033,"Golgi membrane; cell death; early endosome membrane; late endosome membrane; locomotory behavior; myelin assembly; negative regulation of myelination; neuron development; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; pigmentation; positive regulation of neuron projection development; small molecule metabolic process; vacuole organization",PF02383;,1.00E-32,CHOYP_FIG4.1.2,,,,,,,FIG4_HUMAN,Homo sapiens (Human),locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] comp155508_c0_seq1,206,63.5922,1.06156348,0,9,,7.00E-19,P32717,Uncharacterized protein YjcS,Putative alkyl/aryl-sulfatase YjcS (EC 3.1.6.-),GO:0016787; GO:0032934,hydrolase activity; sterol binding,PF14864;PF14863;PF00753;,,,,,,,,,YJCS_ECOLI,Escherichia coli (strain K12), comp155512_c0_seq1,203,76.8473,1.0456603,0,4,,2.00E-13,A1B502,RNA pyrophosphohydrolase (EC 3.6.1.-) ((Di)nucleoside polyphosphate hydrolase),RNA pyrophosphohydrolase (EC 3.6.1.-) ((Di)nucleoside polyphosphate hydrolase),GO:0016818; GO:0046872,"hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; metal ion binding",PF00293;,,,,,,,,,RPPH_PARDP,Paracoccus denitrificans (strain Pd 1222), comp155526_c0_seq1,304,40.4605,0.18373693,6,0,,8.00E-06,Q96KM6,Zinc finger protein 512B,Zinc finger protein 512B,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,Z512B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp155578_c0_seq1,246,58.5366,1.2100925,1,5,,6.00E-09,Q10817,Uncharacterized protein Rv2896c/MT2964,,GO:0009294,DNA mediated transformation,,,,,,,,,,Y2896_MYCTU,, comp155579_c0_seq1,226,40.2655,0.90170584,6,0,,3.00E-12,O08688,Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3),Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3),GO:0004198; GO:0009986; GO:0005622; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; cell surface; intracellular; proteolysis,PF01067;PF00648;,,,,,,,,,CAN5_MOUSE,Mus musculus (Mouse),granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508] comp155585_c0_seq1,299,44.4816,0.61336443,9,3,,2.00E-18,Q8IZJ6,"Inactive L-threonine 3-dehydrogenase, mitochondrial","Inactive L-threonine 3-dehydrogenase, mitochondrial (Short chain dehydrogenase/reductase family 14E member 1 pseudogene)",GO:0003824; GO:0044237; GO:0050662; GO:0005739,catalytic activity; cellular metabolic process; coenzyme binding; mitochondrion,PF01370;,,,,,,,,,TDH_HUMAN,Homo sapiens (Human),L-threonine catabolic process to glycine [GO:0019518] comp155588_c0_seq1,212,46.2264,0.46285254,6,0,,8.00E-15,Q13370,"cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)","cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)",GO:0005794; GO:0001525; GO:0007596; GO:0006198; GO:0004119; GO:0005829; GO:0031018; GO:0005783; GO:0042593; GO:0032045; GO:0008286; GO:0016021; GO:0016020; GO:0046872; GO:0016525; GO:0043951; GO:0033629; GO:0050995; GO:0043422; GO:0050796,Golgi apparatus; angiogenesis; blood coagulation; cAMP catabolic process; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; cytosol; endocrine pancreas development; endoplasmic reticulum; glucose homeostasis; guanyl-nucleotide exchange factor complex; insulin receptor signaling pathway; integral to membrane; membrane; metal ion binding; negative regulation of angiogenesis; negative regulation of cAMP-mediated signaling; negative regulation of cell adhesion mediated by integrin; negative regulation of lipid catabolic process; protein kinase B binding; regulation of insulin secretion,PF00233;,5.00E-18,CHOYP_PDE3A.3.3,,,,,,,PDE3B_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cAMP catabolic process [GO:0006198]; cellular response to insulin stimulus [GO:0032869]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of lipid catabolic process [GO:0050995]; signal transduction [GO:0007165] comp155617_c0_seq1,332,47.8916,0.27685652,7,0,,2.00E-18,P78536,Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b),Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b),GO:0030183; GO:0060397; GO:0007219; GO:0051088; GO:0033077; GO:0015629; GO:0016324; GO:0097190; GO:0033627; GO:0009986; GO:0030574; GO:0005737; GO:0007173; GO:0035625; GO:0022617; GO:0002467; GO:0005887; GO:0031293; GO:0045121; GO:0004222; GO:0032717; GO:0048011; GO:0002446; GO:0010820; GO:0030307; GO:0008284; GO:0032722; GO:0031659; GO:0030511; GO:0033025; GO:0042493; GO:0055099; GO:0001666; GO:0032496; GO:0048536; GO:0035313; GO:0008270,"B cell differentiation; JAK-STAT cascade involved in growth hormone signaling pathway; Notch signaling pathway; PMA-inducible membrane protein ectodomain proteolysis; T cell differentiation in thymus; actin cytoskeleton; apical plasma membrane; apoptotic signaling pathway; cell adhesion mediated by integrin; cell surface; collagen catabolic process; cytoplasm; epidermal growth factor receptor signaling pathway; epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; extracellular matrix disassembly; germinal center formation; integral to plasma membrane; membrane protein intracellular domain proteolysis; membrane raft; metalloendopeptidase activity; negative regulation of interleukin-8 production; neurotrophin TRK receptor signaling pathway; neutrophil mediated immunity; positive regulation of T cell chemotaxis; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of chemokine production; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of mast cell apoptotic process; response to drug; response to high density lipoprotein particle stimulus; response to hypoxia; response to lipopolysaccharide; spleen development; wound healing, spreading of epidermal cells; zinc ion binding",PF16698;PF00200;PF01562;,,,,,,,,,ADA17_HUMAN,Homo sapiens (Human),"B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway [GO:0035625]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; proteolysis [GO:0006508]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to high density lipoprotein particle [GO:0055099]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]" comp155622_c0_seq1,213,47.8873,0.49672275,2,3,,2.00E-11,Q86UB9,Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52),Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52),GO:0016021; GO:0005777; GO:0007031,integral to membrane; peroxisome; peroxisome organization,PF02466;PF15982;,,,,,,,,,TM135_HUMAN,Homo sapiens (Human),peroxisome organization [GO:0007031] comp155628_c0_seq1,225,49.3333,1.47330159,7,0,,8.00E-19,Q90922,Netrin-1,Netrin-1,GO:0071944; GO:0005578,cell periphery; proteinaceous extracellular matrix,PF00053;PF00055;PF01759;,,,,,,,,,NET1_CHICK,Gallus gallus (Chicken),"anterior/posterior axon guidance [GO:0033564]; Cdc42 protein signal transduction [GO:0032488]; establishment of nucleus localization [GO:0040023]; inner ear morphogenesis [GO:0042472]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of cell proliferation [GO:0008284]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; single organismal cell-cell adhesion [GO:0016337]; substrate-dependent cell migration, cell extension [GO:0006930]" comp155635_c0_seq1,253,71.9368,1.13945705,0,7,,3.00E-14,Q70LM5,Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)],Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)],GO:0017000; GO:0016853; GO:0016874; GO:0031177,antibiotic biosynthetic process; isomerase activity; ligase activity; phosphopantetheine binding,PF00501;PF13193;PF00668;PF00550;,,,,,,,,,LGRC_BREPA,Brevibacillus parabrevis,antibiotic biosynthetic process [GO:0017000] comp155668_c0_seq1,278,47.8417,0.57513342,5,0,,8.00E-22,Q924A2,Protein capicua homolog,Protein capicua homolog,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16090;PF00505;,8.00E-36,CHOYP_CIC.2.2,,,,,,,CIC_MOUSE,Mus musculus (Mouse),"lung alveolus development [GO:0048286]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp155670_c0_seq1,455,37.5824,0.91148356,7,5,,6.00E-08,A8X6H1,cGMP-dependent protein kinase egl-4 (EC 2.7.11.12) (Egg-laying defective protein 4),cGMP-dependent protein kinase egl-4 (EC 2.7.11.12) (Egg-laying defective protein 4),GO:0005524; GO:0030553; GO:0004692; GO:0046872; GO:0007275,ATP binding; cGMP binding; cGMP-dependent protein kinase activity; metal ion binding; multicellular organismal development,PF00027;PF00069;,3.00E-18,CHOYP_LOC100533328.1.1,,,,,,,EGL4_CAEBR,Caenorhabditis briggsae,chemotaxis [GO:0006935]; multicellular organism development [GO:0007275] comp155678_c0_seq1,327,46.4832,0.62639475,4,5,,2.00E-14,Q5R8I8,Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain],"Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]",GO:0005739; GO:0006646; GO:0004609,mitochondrion; phosphatidylethanolamine biosynthetic process; phosphatidylserine decarboxylase activity,PF02666;,,,,,,,,,PISD_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),phospholipid biosynthetic process [GO:0008654] comp155683_c0_seq1,264,45.0758,0.93311198,5,4,,7.00E-09,Q8CG65,SCO-spondin,SCO-spondin,GO:0007155; GO:0005737; GO:0005615,cell adhesion; cytoplasm; extracellular space,PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;,,,,,,,,,SSPO_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp155684_c0_seq1,411,43.5523,0.31212306,9,0,,1.00E-26,Q810J8,Zinc finger FYVE domain-containing protein 1,Zinc finger FYVE domain-containing protein 1,GO:0005545; GO:0005795; GO:0005783; GO:0046872; GO:0010923; GO:0048471; GO:0005547; GO:0043325,"1-phosphatidylinositol binding; Golgi stack; endoplasmic reticulum; metal ion binding; negative regulation of phosphatase activity; perinuclear region of cytoplasm; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding",PF01363;,,,,,,,,,ZFYV1_MOUSE,Mus musculus (Mouse),cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923] comp155697_c0_seq1,255,44.3137,0.16040347,8,0,,3.00E-18,Q5R9B8,DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP),DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP),GO:0080008; GO:0005634; GO:0016567,Cul4-RING ubiquitin ligase complex; nucleus; protein ubiquitination,PF00400;,1.00E-14,CHOYP_DCAF6.2.2,,,,,,,DCAF6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein ubiquitination [GO:0016567] comp155699_c0_seq1,228,43.8596,0.64352904,3,0,,9.00E-12,B2RRL2,Jerky protein homolog-like,Jerky protein homolog-like,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,JERKL_MOUSE,Mus musculus (Mouse), comp155704_c0_seq1,232,50.431,0.41957562,8,0,,6.00E-06,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp155719_c0_seq1,313,44.7284,0.32205457,5,0,,6.00E-32,Q8R5L3,Vam6/Vps39-like protein,Vam6/Vps39-like protein,GO:0006886; GO:0031902; GO:0005765; GO:0005083; GO:0016192,intracellular protein transport; late endosome membrane; lysosomal membrane; small GTPase regulator activity; vesicle-mediated transport,PF00637;PF00780;PF10366;PF10367;,2.00E-45,CHOYP_LOC100378848.1.1,,,,,,,VPS39_MOUSE,Mus musculus (Mouse),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]; vesicle-mediated transport [GO:0016192]" comp155730_c0_seq1,203,61.5764,1.22381687,0,7,,1.00E-11,P0AFF9,Transcription termination/antitermination protein NusA,Transcription termination/antitermination protein NusA,GO:0003677; GO:0006281; GO:0006353; GO:0003723; GO:0005737; GO:0000166; GO:0003700; GO:0031564,"DNA binding; DNA repair; DNA-dependent transcription, termination; RNA binding; cytoplasm; nucleotide binding; sequence-specific DNA binding transcription factor activity; transcription antitermination",PF13184;PF08529;PF00575;,,,,,,,,,NUSA_SHIFL,Shigella flexneri,"DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]" comp155732_c0_seq1,229,48.0349,0.45863287,6,0,,2.00E-16,Q9DAX9,Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2),Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2),GO:0030659; GO:0046907; GO:0005874; GO:0005634; GO:0015031,cytoplasmic vesicle membrane; intracellular transport; microtubule; nucleus; protein transport,PF13374;,,,,,,,,,APBP2_MOUSE,Mus musculus (Mouse),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp155743_c0_seq1,214,38.3178,0.85319323,7,0,,1.00E-14,Q08DC7,Regulator of G-protein signaling 19 (RGS19),Regulator of G-protein signaling 19 (RGS19),GO:0005096; GO:0006914; GO:0005737; GO:0005886; GO:0038032,GTPase activator activity; autophagy; cytoplasm; plasma membrane; termination of G-protein coupled receptor signaling pathway,PF00615;,8.00E-16,CHOYP_AGAP_AGAP007127.1.1,,,,,,,RGS19_BOVIN,Bos taurus (Bovine),"autophagy [GO:0006914]; cell death [GO:0008219]; cell differentiation [GO:0030154]; cellular response to organic cyclic compound [GO:0071407]; dorsal/ventral axis specification [GO:0009950]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of catenin import into nucleus [GO:0035412]; regulation of transcription, DNA-templated [GO:0006355]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp155747_c0_seq1,211,40.7583,0.34472319,6,0,,1.00E-06,Q3KR37,GRAM domain-containing protein 1B,GRAM domain-containing protein 1B,GO:0016021,integral to membrane,PF16016;PF02893;,,,,,,,,,GRM1B_HUMAN,Homo sapiens (Human), comp155758_c0_seq1,230,40.4348,0.42739013,4,1,,3.00E-07,A2A3L6,Tetratricopeptide repeat protein 24 (TPR repeat protein 24),Tetratricopeptide repeat protein 24 (TPR repeat protein 24),,,PF13176;,,,,,,,,,TTC24_HUMAN,Homo sapiens (Human), comp155759_c0_seq1,226,40.2655,0.98984496,6,0,,5.00E-20,Q9P2E3,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,,,,,,,,,ZNFX1_HUMAN,Homo sapiens (Human), comp155767_c0_seq1,220,44.0909,1.07473485,5,0,,3.00E-12,Q2V2M9,FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2),GO:0030018; GO:0007015; GO:0005737; GO:0005856; GO:0030837; GO:0005730; GO:0045214,Z disc; actin filament organization; cytoplasm; cytoskeleton; negative regulation of actin filament polymerization; nucleolus; sarcomere organization,PF02181;,6.00E-49,CHOYP_FHOD3.1.2,,,,,,,FHOD3_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] comp155769_c0_seq1,240,43.3333,0.26897788,2,4,,2.00E-26,Q93650,Putative glutaminase 3 (GLS) (EC 3.5.1.2) (L-glutamine amidohydrolase),Putative glutaminase 3 (GLS) (EC 3.5.1.2) (L-glutamine amidohydrolase),GO:0004359; GO:0006541,glutaminase activity; glutamine metabolic process,PF12796;PF04960;,,,,,,,,,GLSB_CAEEL,Caenorhabditis elegans,glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543] comp155772_c0_seq1,271,43.1734,1.20711703,7,0,,1.00E-12,P91887,Aminopeptidase N (AP-N) (EC 3.4.11.2) (Apn1) (Microsomal aminopeptidase),Aminopeptidase N (AP-N) (EC 3.4.11.2) (Apn1) (Microsomal aminopeptidase),GO:0004177; GO:0031225; GO:0008237; GO:0005886; GO:0006508; GO:0008270,aminopeptidase activity; anchored to membrane; metallopeptidase activity; plasma membrane; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_PLUXY,Plutella xylostella (Diamondback moth) (Plutella maculipennis), comp155780_c0_seq1,379,46.9657,0.24136347,12,0,,3.00E-31,Q9MZD1,Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),GO:0016021; GO:0005765; GO:0015293,integral to membrane; lysosomal membrane; symporter activity,PF07690;,3.00E-36,CHOYP_LOC100121099.1.1,,,,,,,S17A5_SHEEP,Ovis aries (Sheep), comp155794_c0_seq1,227,48.0176,0.62595587,4,0,,2.00E-07,Q08DY9,Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12],GO:0006915; GO:0004197; GO:0005737; GO:0006508,apoptotic process; cysteine-type endopeptidase activity; cytoplasm; proteolysis,,,,,,,,,,CASP3_BOVIN,Bos taurus (Bovine),erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; keratinocyte differentiation [GO:0030216]; neuron differentiation [GO:0030182] comp155795_c0_seq1,241,43.1535,0.44898732,6,0,,4.00E-22,Q17QU5,Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8),Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8),GO:0005737; GO:0032008; GO:0030838; GO:0050731; GO:0032314,cytoplasm; positive regulation of TOR signaling cascade; positive regulation of actin filament polymerization; positive regulation of peptidyl-tyrosine phosphorylation; regulation of Rac GTPase activity,PF00400;,3.00E-28,CHOYP_LOC100376733.1.1,1.00E-23,ruditapes_c5646,,,,,LST8_BOVIN,Bos taurus (Bovine), comp155802_c0_seq1,292,44.1781,0.35386888,3,6,,2.00E-26,Q622K8,Unconventional myosin heavy chain 6,Unconventional myosin heavy chain 6,GO:0005524; GO:0005737; GO:0003774; GO:0016459; GO:0008134,ATP binding; cytoplasm; motor activity; myosin complex; transcription factor binding,PF00373;PF00612;PF00063;PF00784;,2.00E-11,CHOYP_PHUM_PHUM430580.1.1,,,,,,,HUM6_CAEBR,Caenorhabditis briggsae, comp155816_c0_seq1,204,46.5686,0.82886089,6,0,,2.00E-26,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,1.00E-26,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp155821_c0_seq1,227,45.3744,0.43914566,5,0,,1.00E-12,Q9FT51,ABC transporter G family member 27 (ABC transporter ABCG.27) (AtABCG27) (Probable white-brown complex homolog protein 28) (AtWBC28),ABC transporter G family member 27 (ABC transporter ABCG.27) (AtABCG27) (Probable white-brown complex homolog protein 28) (AtWBC28),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF01061;PF00005;,4.00E-20,CHOYP_LOC100166121.1.1,,,,,,,AB27G_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp155831_c0_seq1,341,41.9355,0.53542535,9,0,,3.00E-23,Q9NYL5,24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.13.99) (Cytochrome P450 39A1) (hCYP39A1) (Oxysterol 7-alpha-hydroxylase),24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (hCYP39A1) (Oxysterol 7-alpha-hydroxylase),GO:0033782; GO:0006699; GO:0030573; GO:0006707; GO:0007586; GO:0005789; GO:0020037; GO:0005506; GO:0008396; GO:0008387; GO:0016125; GO:0006805,24-hydroxycholesterol 7alpha-hydroxylase activity; bile acid biosynthetic process; bile acid catabolic process; cholesterol catabolic process; digestion; endoplasmic reticulum membrane; heme binding; iron ion binding; oxysterol 7-alpha-hydroxylase activity; steroid 7-alpha-hydroxylase activity; sterol metabolic process; xenobiotic metabolic process,PF00067;,,,,,,,,,CP39A_HUMAN,Homo sapiens (Human),bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; sterol metabolic process [GO:0016125] comp155848_c0_seq1,259,44.7876,0.85425407,5,0,,,,,,,,,4.00E-14,CHOYP_contig_052751,,,,,,,,, comp155853_c0_seq1,216,43.9815,0.38510142,4,0,,,,,,,,,,,6.00E-15,ruditapes_c25346,,,,,,, comp155878_c0_seq1,282,36.8794,0.2121466,5,2,,,,,,,,,1.00E-14,CHOYP_LOC100375143.1.1,,,,,,,,, comp155879_c0_seq1,206,49.5146,0.48956613,5,0,,2.00E-06,P33224,Putative acyl-CoA dehydrogenase AidB (EC 1.3.99.-),Putative acyl-CoA dehydrogenase AidB (EC 1.3.99.-),GO:0005737; GO:0008470; GO:0045892; GO:0006950; GO:0043565,"cytoplasm; isovaleryl-CoA dehydrogenase activity; negative regulation of transcription, DNA-dependent; response to stress; sequence-specific DNA binding",PF00441;PF02770;,,,,,,,,,AIDB_ECOLI,Escherichia coli (strain K12),"cellular response to DNA damage stimulus [GO:0006974]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]" comp155890_c0_seq1,241,40.249,0.62858225,5,0,,3.00E-09,Q5STE3,Follistatin-related protein 4 (Follistatin-like protein 4) (m-D/Bsp120I 1-1),Follistatin-related protein 4 (Follistatin-like protein 4) (m-D/Bsp120I 1-1),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07648;,,,,,,,,,FSTL4_MOUSE,Mus musculus (Mouse),negative regulation of brain-derived neurotrophic factor receptor signaling pathway [GO:0031549]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; regulation of collateral sprouting [GO:0048670] comp155891_c0_seq1,295,42.7119,1.06121578,7,0,,2.00E-08,Q01791,Protein hunchback,Protein hunchback,GO:0003677; GO:0046872; GO:0005634; GO:0040034; GO:0035282; GO:0000981; GO:0006366,"DNA binding; metal ion binding; nucleus; regulation of development, heterochronic; segmentation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter",,,,,,,,,,HUNB_TRICA,Tribolium castaneum (Red flour beetle),"regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]" comp155897_c0_seq1,249,50.6024,1.02434431,6,0,,5.00E-22,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp155899_c0_seq1,223,35.8744,1.28002574,6,0,,2.00E-08,Q02974,Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),GO:0005524; GO:0016052; GO:0006000; GO:0004454; GO:0009750; GO:0009749; GO:0032868; GO:0009744; GO:0010043,ATP binding; carbohydrate catabolic process; fructose metabolic process; ketohexokinase activity; response to fructose stimulus; response to glucose stimulus; response to insulin stimulus; response to sucrose stimulus; response to zinc ion,PF00294;,,,,,,,,,KHK_RAT,Rattus norvegicus (Rat),carbohydrate catabolic process [GO:0016052]; fructose metabolic process [GO:0006000]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043] comp155908_c0_seq1,345,42.8986,0.18986807,2,4,,7.00E-37,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,4.00E-47,CHOYP_NBEL1.1.1,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp155922_c0_seq1,244,44.2623,0.92422677,3,3,,3.00E-10,P47989,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0006919; GO:0005829; GO:0009055; GO:0005576; GO:0050660; GO:0005506; GO:0007595; GO:0043546; GO:0045602; GO:0001937; GO:0010629; GO:0051898; GO:0001933; GO:1900747; GO:2001213; GO:0005777; GO:1900745; GO:2000379; GO:0006195; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; cytosol; electron carrier activity; extracellular region; flavin adenine dinucleotide binding; iron ion binding; lactation; molybdopterin cofactor binding; negative regulation of endothelial cell differentiation; negative regulation of endothelial cell proliferation; negative regulation of gene expression; negative regulation of protein kinase B signaling cascade; negative regulation of protein phosphorylation; negative regulation of vascular endothelial growth factor signaling pathway; negative regulation of vasculogenesis; peroxisome; positive regulation of p38MAPK cascade; positive regulation of reactive oxygen species metabolic process; purine nucleotide catabolic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; lactation [GO:0007595]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of gene expression [GO:0010629]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; negative regulation of vasculogenesis [GO:2001213]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; purine nucleotide catabolic process [GO:0006195]; xanthine catabolic process [GO:0009115] comp155924_c0_seq1,227,36.5639,0.7944405,6,0,,1.00E-15,Q5DRA3,Protocadherin gamma-C4 (PCDH-gamma-C4),Protocadherin gamma-C4 (PCDH-gamma-C4),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF15974;,,,,,,,,,PCDGL_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp155925_c0_seq1,320,48.75,0.63324636,7,0,,,,,,,,,5.00E-14,CHOYP_LOC579367.1.1,,,,,,,,, comp155949_c0_seq1,221,52.4887,0.46416721,5,2,,1.00E-26,Q8QFV0,Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,2.00E-30,CHOYP_AGAP_AGAP007585.1.1,,,,,,,KCNT1_CHICK,Gallus gallus (Chicken), comp155950_c0_seq1,295,48.4746,1.04267343,7,0,,3.00E-16,Q58DK1,"Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)","Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)",GO:0004095; GO:0006635; GO:0016021; GO:0005741; GO:0006810,carnitine O-palmitoyltransferase activity; fatty acid beta-oxidation; integral to membrane; mitochondrial outer membrane; transport,PF00755;PF16484;,6.00E-19,CHOYP_LOC577934.1.1,,,,,,,CPT1B_BOVIN,Bos taurus (Bovine),fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810] comp155957_c0_seq1,205,40.4878,0.59815593,5,0,,2.00E-29,Q10751,Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),GO:0004180; GO:0016021; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,2.00E-23,CHOYP_ACE.2.4,,,,,,,ACE_CHICK,Gallus gallus (Chicken), comp155970_c0_seq1,243,40.7407,0.50206612,6,0,,6.00E-23,Q5F2L1,"Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)","Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)",GO:0032580; GO:0046920; GO:0036065; GO:0016021; GO:0006486,Golgi cisterna membrane; alpha-(1->3)-fucosyltransferase activity; fucosylation; integral to membrane; protein glycosylation,PF17039;PF00852;,7.00E-11,CHOYP_LOC100369391.1.1,,,,,,,FUT10_RAT,Rattus norvegicus (Rat),protein glycosylation [GO:0006486] comp155980_c0_seq1,254,44.4882,0.48023343,5,0,,4.00E-10,Q9CWL2,Zinc finger protein castor homolog 1 (Castor-related protein),Zinc finger protein castor homolog 1 (Castor-related protein),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,2.00E-37,CHOYP_DNAH5.2.2,,,,,,,CASZ1_MOUSE,Mus musculus (Mouse),"central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]" comp155981_c0_seq1,217,47.4654,0.68608853,5,0,,1.00E-06,Q5SUS0,F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10),F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10),,,PF00400;,,,,,,,,,FBW10_MOUSE,Mus musculus (Mouse), comp156021_c0_seq1,240,48.75,0.30603706,1,4,,,,,,,,,2.00E-18,CHOYP_LOC658322.1.1,,,,,,,,, comp156024_c0_seq1,217,45.6221,0.71359944,2,0,,9.00E-16,A2RV61,GTPase-activating protein and VPS9 domain-containing protein 1,GTPase-activating protein and VPS9 domain-containing protein 1,GO:0032794; GO:0005096; GO:0005829; GO:0006897; GO:0005768; GO:0005085; GO:0016020; GO:0043547; GO:0051223; GO:0051056; GO:0007165,GTPase activating protein binding; GTPase activator activity; cytosol; endocytosis; endosome; guanyl-nucleotide exchange factor activity; membrane; positive regulation of GTPase activity; regulation of protein transport; regulation of small GTPase mediated signal transduction; signal transduction,PF00616;PF02204;,,,,,,,,,GAPD1_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165] comp156028_c0_seq1,252,43.6508,0.92490656,3,3,,4.00E-09,Q0EEE2,Patched domain-containing protein 3 (RND-type protein RNDEu-3),Patched domain-containing protein 3 (RND-type protein RNDEu-3),GO:0008158; GO:0016021,hedgehog receptor activity; integral to membrane,PF02460;,3.00E-21,CHOYP_LOC100372915.5.7,,,,,,,PTHD3_MOUSE,Mus musculus (Mouse), comp156029_c0_seq1,213,39.4366,0.48637436,0,1,,5.00E-15,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp156031_c0_seq1,238,42.8571,0.7396649,3,3,,3.00E-13,P0C1S9,Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-),Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-),GO:0016021; GO:0016042; GO:0046872; GO:0005886; GO:0004806,integral to membrane; lipid catabolic process; metal ion binding; plasma membrane; triglyceride lipase activity,PF01764;,,,,,,,,,DGLB_RAT,Rattus norvegicus (Rat),lipid catabolic process [GO:0016042]; transport [GO:0006810] comp156054_c0_seq1,207,38.1643,0.4149033,3,3,,1.00E-11,Q5M827,"Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase)","Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase)",GO:0005737; GO:0046872; GO:0030224; GO:0005634; GO:0008127; GO:0006355; GO:0003712; GO:0006351,"cytoplasm; metal ion binding; monocyte differentiation; nucleus; quercetin 2,3-dioxygenase activity; regulation of transcription, DNA-dependent; transcription cofactor activity; transcription, DNA-dependent",PF02678;PF05726;,,,,,,,,,PIR_RAT,Rattus norvegicus (Rat),"monocyte differentiation [GO:0030224]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp156064_c0_seq1,286,33.9161,0.38064126,5,0,,,,,,,,,4.00E-14,CHOYP_LOC584740.1.2,,,,,,,,, comp156067_c0_seq1,222,46.3964,0.95747454,5,0,,2.00E-09,P53354,"Alpha-amylase I (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)","Alpha-amylase I (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)",GO:0004556; GO:0005975; GO:0005576; GO:0046872,alpha-amylase activity; carbohydrate metabolic process; extracellular region; metal ion binding,PF00128;PF02806;,,,,,,,,,AMY1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),carbohydrate metabolic process [GO:0005975] comp156079_c0_seq1,249,38.5542,2.76579737,10,0,,,,,,,,,6.00E-12,CHOYP_contig_054881,,,,,,,,, comp156089_c0_seq1,261,47.8927,0.55894154,4,0,,6.00E-22,Q63ZU0,Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase),Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase),GO:0042110; GO:0006154; GO:0004000; GO:0030054; GO:0060205; GO:0005829; GO:0009897; GO:0043103; GO:0046103; GO:0060169; GO:0009117; GO:0009168; GO:0008270,T cell activation; adenosine catabolic process; adenosine deaminase activity; cell junction; cytoplasmic membrane-bounded vesicle lumen; cytosol; external side of plasma membrane; hypoxanthine salvage; inosine biosynthetic process; negative regulation of adenosine receptor signaling pathway; nucleotide metabolic process; purine ribonucleoside monophosphate biosynthetic process; zinc ion binding,PF00962;,,,,,,,,,ADA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),adenosine catabolic process [GO:0006154]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110] comp156091_c0_seq1,358,42.1788,0.94974286,6,0,,1.00E-15,P15541,Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0005886; GO:0006508; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; plasma membrane; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_RABIT,Oryctolagus cuniculus (Rabbit),angiogenesis [GO:0001525]; cell differentiation [GO:0030154] comp156101_c0_seq1,240,38.75,0.34894428,5,0,,2.00E-13,Q5JWR5,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,3.00E-22,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp156104_c0_seq1,217,45.1613,0.27284685,6,0,,3.00E-19,Q9BXS9,Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1),Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1),GO:0030165; GO:0038166; GO:0015301; GO:0016324; GO:0016323; GO:0015106; GO:0031526; GO:0071320; GO:0071332; GO:0071346; GO:0005254; GO:0034707; GO:0015108; GO:0030659; GO:0005783; GO:0042045; GO:0015660; GO:0015659; GO:0016021; GO:0005887; GO:0050892; GO:0051454; GO:0015797; GO:0019531; GO:0046724; GO:0005886; GO:2001150; GO:0070528; GO:0051453; GO:0008271; GO:0048240; GO:0097225; GO:0015116; GO:0008272; GO:0030321; GO:0012506,PDZ domain binding; angiotensin-mediated signaling pathway; anion:anion antiporter activity; apical plasma membrane; basolateral plasma membrane; bicarbonate transmembrane transporter activity; brush border membrane; cellular response to cAMP; cellular response to fructose stimulus; cellular response to interferon-gamma; chloride channel activity; chloride channel complex; chloride transmembrane transporter activity; cytoplasmic vesicle membrane; endoplasmic reticulum; epithelial fluid transport; formate efflux transmembrane transporter activity; formate uptake transmembrane transporter activity; integral to membrane; integral to plasma membrane; intestinal absorption; intracellular pH elevation; mannitol transport; oxalate transmembrane transporter activity; oxalic acid secretion; plasma membrane; positive regulation of dipeptide transmembrane transport; protein kinase C signaling cascade; regulation of intracellular pH; secondary active sulfate transmembrane transporter activity; sperm capacitation; sperm midpiece; sulfate transmembrane transporter activity; sulfate transport; transepithelial chloride transport; vesicle membrane,PF01740;PF00916;,5.00E-18,CHOYP_LOC100552593.2.3,,,,,,,S26A6_HUMAN,Homo sapiens (Human),angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to fructose stimulus [GO:0071332]; cellular response to interferon-gamma [GO:0071346]; chloride transport [GO:0006821]; epithelial fluid transport [GO:0042045]; formate transport [GO:0015724]; intestinal absorption [GO:0050892]; intracellular pH elevation [GO:0051454]; ion transport [GO:0006811]; mannitol transport [GO:0015797]; oxalate transport [GO:0019532]; oxalic acid secretion [GO:0046724]; positive regulation of dipeptide transmembrane transport [GO:2001150]; protein kinase C signaling [GO:0070528]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]; sulfate transport [GO:0008272]; transepithelial chloride transport [GO:0030321]; transepithelial transport [GO:0070633] comp156115_c0_seq1,375,42.6667,0.89524446,6,2,,3.00E-09,Q9Y4K0,Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14),Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14),GO:0007568; GO:0005604; GO:0007155; GO:0003682; GO:0005694; GO:0030199; GO:0005507; GO:0009055; GO:0043542; GO:0001935; GO:0001837; GO:0005615; GO:0016570; GO:0016020; GO:0035064; GO:0045892; GO:0005634; GO:0070492; GO:0032332; GO:0018277; GO:0004720; GO:0046688; GO:0001666; GO:0005044; GO:0002040; GO:0003714; GO:0006351,"aging; basement membrane; cell adhesion; chromatin binding; chromosome; collagen fibril organization; copper ion binding; electron carrier activity; endothelial cell migration; endothelial cell proliferation; epithelial to mesenchymal transition; extracellular space; histone modification; membrane; methylated histone residue binding; negative regulation of transcription, DNA-dependent; nucleus; oligosaccharide binding; positive regulation of chondrocyte differentiation; protein deamination; protein-lysine 6-oxidase activity; response to copper ion; response to hypoxia; scavenger receptor activity; sprouting angiogenesis; transcription corepressor activity; transcription, DNA-dependent",PF01186;PF00530;,,,3.00E-16,ruditapes_c14950,,,,,LOXL2_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; histone modification [GO:0016570]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidation-reduction process [GO:0055114]; positive regulation of chondrocyte differentiation [GO:0032332]; protein deamination [GO:0018277]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]" comp156119_c0_seq1,307,44.6254,0.66437288,6,0,,6.00E-20,P12785,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0070402; GO:0004313; GO:0004314; GO:0006084; GO:0071353; GO:0008144; GO:0047117; GO:0004319; GO:0006633; GO:0004312; GO:0042587; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0005886; GO:0042803; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; NADPH binding; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; acetyl-CoA metabolic process; cellular response to interleukin-4; drug binding; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; fatty acid synthase activity; glycogen granule; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; plasma membrane; protein homodimerization activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,,,,,,,,,FAS_RAT,Rattus norvegicus (Rat),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649] comp156155_c0_seq1,233,51.5021,0.260294,6,0,,3.00E-14,Q6P2S7,Tetratricopeptide repeat protein GNN (TPR repeat protein GNN) (Grp94-neighboring nucleotidase),Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase),GO:0005737,cytoplasm,PF13271;,,,,,,,,,GNN_HUMAN,Homo sapiens (Human), comp156157_c0_seq1,309,44.6602,0.78201366,5,0,,4.00E-19,P74615,Uncharacterized protein sll1483,Uncharacterized protein sll1483,GO:0030288,outer membrane-bounded periplasmic space,PF02469;,,,,,,,,,Y1483_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa), comp156172_c0_seq1,206,45.1456,0.57501355,5,0,,4.00E-12,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp156173_c0_seq1,229,58.952,1.13302653,1,1,,1.00E-06,P64892,UPF0749 protein Mb1854,UPF0749 protein Mb1854,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF05949;,,,,,,,,,Y1854_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp156205_c0_seq1,257,42.0233,0.35697531,6,1,,1.00E-26,A7RU46,Nck-associated protein 1 homolog,Nck-associated protein 1 homolog,GO:0007155,cell adhesion,PF09735;,,,,,,,,,NAPA_NEMVE,Nematostella vectensis (Starlet sea anemone),cell adhesion [GO:0007155] comp156207_c0_seq1,413,48.184,0.46028166,6,0,,5.00E-24,Q7Z304,MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan),MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan),GO:0005783; GO:0005539; GO:0005614; GO:0016020; GO:0019800,endoplasmic reticulum; glycosaminoglycan binding; interstitial matrix; membrane; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan,PF00629;,1.00E-22,CHOYP_NEMVEDRAFT_V1G239043.2.6,,,,,,,MAMC2_HUMAN,Homo sapiens (Human), comp156214_c0_seq1,241,45.6432,0.72216097,8,0,,1.00E-24,Q8R4C2,RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE),RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE),GO:0046872; GO:0005634,metal ion binding; nucleus,PF01363;PF02759;,4.00E-33,CHOYP_LOC100372467.1.1,,,,,,,RUFY2_MOUSE,Mus musculus (Mouse), comp156231_c0_seq1,201,44.2786,0.51011364,5,0,,4.00E-09,O15360,Fanconi anemia group A protein (Protein FACA),Fanconi anemia group A protein (Protein FACA),GO:0006281; GO:0043240; GO:0005737; GO:0008585; GO:0008584; GO:0007140; GO:0006461; GO:0042127,DNA repair; Fanconi anaemia nuclear complex; cytoplasm; female gonad development; male gonad development; male meiosis; protein complex assembly; regulation of cell proliferation,PF03511;PF15865;,,,,,,,,,FANCA_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; female gonad development [GO:0008585]; interstrand cross-link repair [GO:0036297]; male gonad development [GO:0008584]; male meiosis [GO:0007140]; protein complex assembly [GO:0006461]; regulation of cell proliferation [GO:0042127] comp156255_c0_seq1,244,45.082,0.34016538,6,0,,7.00E-23,Q8N3P4,Vacuolar protein sorting-associated protein 8 homolog,Vacuolar protein sorting-associated protein 8 homolog,GO:0008270,zinc ion binding,PF12816;,,,,,,,,,VPS8_HUMAN,Homo sapiens (Human),endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031] comp156274_c0_seq1,251,45.8167,1.22406315,7,0,,9.00E-11,Q9BYK8,"Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)","Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)",GO:0005524; GO:0003677; GO:0044255; GO:0004386; GO:0030374; GO:0046872; GO:0005654; GO:0045944; GO:0044281; GO:0006351,"ATP binding; DNA binding; cellular lipid metabolic process; helicase activity; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; transcription, DNA-dependent",,,,,,,,,,PR285_HUMAN,Homo sapiens (Human),"cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp156296_c0_seq1,274,41.9708,0.1720924,5,0,,2.00E-37,Q5T2R2,Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1),Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1),GO:0008299; GO:0046872; GO:0005759; GO:0046982; GO:0051290; GO:0000010; GO:0050347; GO:0006744,isoprenoid biosynthetic process; metal ion binding; mitochondrial matrix; protein heterodimerization activity; protein heterotetramerization; trans-hexaprenyltranstransferase activity; trans-octaprenyltranstransferase activity; ubiquinone biosynthetic process,PF00348;,,,,,,,,,DPS1_HUMAN,Homo sapiens (Human),isoprenoid biosynthetic process [GO:0008299]; protein heterotetramerization [GO:0051290]; ubiquinone biosynthetic process [GO:0006744] comp15630_c0_seq1,212,42.9245,1.13300393,5,0,,2.00E-07,O54784,Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (ZIP-kinase),Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (ZIP-kinase),GO:0005524; GO:0016605; GO:0097190; GO:0071346; GO:0016568; GO:0000775; GO:0005737; GO:0007243; GO:0005815; GO:0017148; GO:0030182; GO:0090263; GO:2001241; GO:0046777; GO:0042803; GO:0004674; GO:0006355; GO:0006351,"ATP binding; PML body; apoptotic signaling pathway; cellular response to interferon-gamma; chromatin modification; chromosome, centromeric region; cytoplasm; intracellular protein kinase cascade; microtubule organizing center; negative regulation of translation; neuron differentiation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;,,,,,,,,,DAPK3_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; chromatin modification [GO:0016568]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of myosin II filament organization [GO:0043519]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp156320_c0_seq1,277,42.9603,0.57101683,6,0,,2.00E-17,Q923J6,"Dynein heavy chain 12, axonemal (Bm259)","Dynein heavy chain 12, axonemal (Bm259)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;,1.00E-27,CHOYP_LOC587136.1.3,,,,,,,DYH12_RAT,Rattus norvegicus (Rat),microtubule-based movement [GO:0007018] comp156353_c0_seq1,268,50.7463,0.75644575,7,0,,2.00E-06,Q8N328,PiggyBac transposable element-derived protein 3,PiggyBac transposable element-derived protein 3,,,PF13843;,,,,,,,,,PGBD3_HUMAN,Homo sapiens (Human), comp156358_c0_seq1,330,49.0909,0.5045778,7,1,,6.00E-16,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp156373_c0_seq1,278,40.6475,1.07931764,7,0,,3.00E-10,Q8JZQ5,Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase),Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase),GO:0009308; GO:0005261; GO:0097185; GO:0071280; GO:0035874; GO:0071420; GO:0005507; GO:0052597; GO:0008144; GO:0005615; GO:0008201; GO:0052598; GO:0052599; GO:0005886; GO:0008131; GO:0052600; GO:0032403; GO:0048038; GO:0004872; GO:0046677; GO:0042493; GO:0005923; GO:0008270,"amine metabolic process; cation channel activity; cellular response to azide; cellular response to copper ion; cellular response to copper ion starvation; cellular response to histamine; copper ion binding; diamine oxidase activity; drug binding; extracellular space; heparin binding; histamine oxidase activity; methylputrescine oxidase activity; plasma membrane; primary amine oxidase activity; propane-1,3-diamine oxidase activity; protein complex binding; quinone binding; receptor activity; response to antibiotic; response to drug; tight junction; zinc ion binding",PF01179;PF02727;PF02728;,,,,,,,,,ABP1_MOUSE,Mus musculus (Mouse),amiloride transport [GO:0015898]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; response to drug [GO:0042493] comp156374_c0_seq1,297,44.4444,0.61926354,6,0,,7.00E-21,Q86TV6,Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),,,PF13181;,,,,,,,,,TTC7B_HUMAN,Homo sapiens (Human),establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854] comp156383_c0_seq1,381,40.6824,0.44522451,8,1,,2.00E-13,Q9UJX3,Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7),Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7),GO:0005680; GO:0031145; GO:0051301; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination,PF13181;,,,,,,,,,APC7_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp156405_c0_seq1,352,43.1818,0.91816243,9,0,,8.00E-10,O60245,Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh),Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh),GO:0005509; GO:0007156; GO:0005887,calcium ion binding; homophilic cell adhesion; integral to plasma membrane,PF00028;PF08266;PF08374;,,,,,,,,,PCDH7_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; platelet degranulation [GO:0002576] comp156414_c0_seq1,310,43.5484,0.62422594,3,0,,4.00E-10,Q8CFW1,Anoctamin-2 (Transmembrane protein 16B),Anoctamin-2 (Transmembrane protein 16B),GO:0034707; GO:0005229; GO:0005886,chloride channel complex; intracellular calcium activated chloride channel activity; plasma membrane,PF16178;PF04547;,1.00E-14,CHOYP_BRAFLDRAFT_126668.1.2,,,,,,,ANO2_MOUSE,Mus musculus (Mouse),chloride transport [GO:0006821] comp156425_c0_seq1,224,42.4107,0.80502499,0,9,,6.00E-08,Q8CIV7,Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO),Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO),GO:0003677; GO:0001525; GO:0009953; GO:0048557; GO:0060214; GO:0001947; GO:0060347; GO:0060716; GO:0046872; GO:0045746; GO:0008285; GO:0045617; GO:0010944; GO:0045892; GO:0001755; GO:0001842; GO:0005634; GO:0045893; GO:0051726; GO:0010837; GO:0000981; GO:0044212,"DNA binding; angiogenesis; dorsal/ventral pattern formation; embryonic digestive tract morphogenesis; endocardium formation; heart looping; heart trabecula formation; labyrinthine layer blood vessel development; metal ion binding; negative regulation of Notch signaling pathway; negative regulation of cell proliferation; negative regulation of keratinocyte differentiation; negative regulation of transcription by competitive promoter binding; negative regulation of transcription, DNA-dependent; neural crest cell migration; neural fold formation; nucleus; positive regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of keratinocyte proliferation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription regulatory region DNA binding",,,,,,,,,,OVOL2_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; dorsal/ventral pattern formation [GO:0009953]; embryonic digestive tract morphogenesis [GO:0048557]; endocardium formation [GO:0060214]; epidermal cell differentiation [GO:0009913]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of keratinocyte proliferation [GO:0010837]" comp156445_c0_seq1,255,38.0392,0.21824718,4,0,,4.00E-29,Q96GX5,Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L),Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L),GO:0005524; GO:0000086; GO:0051301; GO:0005813; GO:0032154; GO:0005737; GO:0007067; GO:0034048; GO:0005654; GO:0051721; GO:0004674; GO:0051726; GO:0006974,ATP binding; G2/M transition of mitotic cell cycle; cell division; centrosome; cleavage furrow; cytoplasm; mitosis; negative regulation of protein phosphatase type 2A activity; nucleoplasm; protein phosphatase 2A binding; protein serine/threonine kinase activity; regulation of cell cycle; response to DNA damage stimulus,PF00069;,3.00E-21,CHOYP_GWL.1.1,,,,,,,GWL_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; negative regulation of protein phosphatase type 2A activity [GO:0034048]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell cycle [GO:0051726] comp156458_c0_seq1,242,49.1736,0.34615976,5,0,,1.00E-25,Q2PC20,"Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)","Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)",GO:0046872; GO:0005759; GO:0006470; GO:0004722,metal ion binding; mitochondrial matrix; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,PPM1K_BOVIN,Bos taurus (Bovine), comp156485_c0_seq1,203,45.8128,1.23812528,2,3,,9.00E-09,P49457,Complement decay-accelerating factor (CD antigen CD55) (Fragment),Complement decay-accelerating factor (CD antigen CD55) (Fragment),GO:0031225; GO:0006958; GO:0045087; GO:0005886,"anchored to membrane; complement activation, classical pathway; innate immune response; plasma membrane",PF00084;,,,,,,,,,DAF_PONPY,Pongo pygmaeus (Bornean orangutan),"complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]" comp156493_c0_seq1,201,39.801,0.64128571,5,0,,2.00E-10,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp156507_c0_seq1,346,37.2832,0.17135946,7,0,,6.00E-12,O00534,von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein),von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein),GO:0005634,nucleus,PF08487;PF13768;,,,,,,,,,VMA5A_HUMAN,Homo sapiens (Human), comp156562_c0_seq1,227,38.326,0.25909594,4,0,,2.00E-34,Q8MV48,N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),GO:0000139; GO:0005795; GO:0016021; GO:0009312; GO:0004653; GO:0006486,Golgi membrane; Golgi stack; integral to membrane; oligosaccharide biosynthetic process; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,3.00E-40,CHOYP_DWIL_GK25256.1.1,,,,,,,GALT7_DROME,Drosophila melanogaster (Fruit fly),oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] comp156570_c0_seq1,239,50.2092,0.26853617,5,0,,1.00E-34,P32189,Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase),Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase),GO:0005524; GO:0005829; GO:0019563; GO:0004370; GO:0006071; GO:0046167; GO:0005741; GO:0019432,ATP binding; cytosol; glycerol catabolic process; glycerol kinase activity; glycerol metabolic process; glycerol-3-phosphate biosynthetic process; mitochondrial outer membrane; triglyceride biosynthetic process,PF02782;PF00370;,5.00E-50,CHOYP_BRAFLDRAFT_224325.3.3,,,,,,,GLPK_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; regulation of fatty acid metabolic process [GO:0019217]; response to cold [GO:0009409]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641] comp156571_c0_seq1,210,43.8095,0.60086792,3,0,,3.00E-19,Q12697,Vacuolar cation-transporting ATPase YPK9 (EC 3.6.3.-) (PARK9 homolog),Vacuolar cation-transporting ATPase YPK9 (EC 3.6.3.-) (PARK9 homolog),GO:0005524; GO:0006200; GO:0019829; GO:0000329; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; fungal-type vacuole membrane; integral to membrane; metal ion binding,PF00122;PF12409;,,,,,,,,,YPK9_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular calcium ion homeostasis [GO:0006874]; cellular manganese ion homeostasis [GO:0030026]; cellular zinc ion homeostasis [GO:0006882] comp156609_c0_seq1,203,37.931,0.98349494,6,0,,6.00E-19,Q5VIY5,Zinc finger protein 468,Zinc finger protein 468,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN468_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp156616_c0_seq1,217,46.5438,0.46031383,4,0,,6.00E-18,P51112,Huntingtin (Huntington disease protein homolog) (HD protein homolog),Huntingtin (Huntington disease protein homolog) (HD protein homolog),GO:0005737; GO:0005634; GO:0048513; GO:0008134,cytoplasm; nucleus; organ development; transcription factor binding,PF12372;,5.00E-12,CHOYP_HD.1.1,,,,,,,HD_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes),animal organ development [GO:0048513] comp156681_c0_seq1,206,45.1456,0.38837688,2,0,,3.00E-20,Q9JJ59,ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL),ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL),GO:0005524; GO:0042288; GO:0042825; GO:0046978; GO:0046979; GO:0005765; GO:0005764; GO:0015421; GO:0042605; GO:0005886; GO:0001916; GO:0015031; GO:0046980,ATP binding; MHC class I protein binding; TAP complex; TAP1 binding; TAP2 binding; lysosomal membrane; lysosome; oligopeptide-transporting ATPase activity; peptide antigen binding; plasma membrane; positive regulation of T cell mediated cytotoxicity; protein transport; tapasin binding,PF00664;PF00005;,,,,,,,,,ABCB9_MOUSE,Mus musculus (Mouse),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]" comp156685_c0_seq1,209,49.2823,0.17004438,4,0,,6.00E-11,Q9BH11,Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4],Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4],GO:0005794; GO:0060478; GO:0007339; GO:0016021; GO:2000360; GO:0005886; GO:0042102; GO:2000344; GO:0002922; GO:0045860; GO:0010737; GO:0070528; GO:0005578; GO:0030141; GO:0004871,Golgi apparatus; acrosomal vesicle exocytosis; binding of sperm to zona pellucida; integral to membrane; negative regulation of binding of sperm to zona pellucida; plasma membrane; positive regulation of T cell proliferation; positive regulation of acrosome reaction; positive regulation of humoral immune response; positive regulation of protein kinase activity; protein kinase A signaling cascade; protein kinase C signaling cascade; proteinaceous extracellular matrix; secretory granule; signal transducer activity,PF00088;PF00100;,,,,,,,,,ZP4_BOVIN,Bos taurus (Bovine),acrosomal vesicle exocytosis [GO:0060478]; binding of sperm to zona pellucida [GO:0007339]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of humoral immune response [GO:0002922]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of T cell proliferation [GO:0042102]; protein kinase A signaling [GO:0010737]; protein kinase C signaling [GO:0070528] comp156703_c0_seq1,213,42.2535,0.22016946,2,4,,2.00E-23,Q61102,"ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)","ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)",GO:0005524; GO:0042626; GO:0006879; GO:0016021; GO:0005743,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cellular iron ion homeostasis; integral to membrane; mitochondrial inner membrane",PF00664;PF00005;,,,,,,,,,ABCB7_MOUSE,Mus musculus (Mouse),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp156705_c0_seq1,258,42.2481,0.44686662,5,0,,9.00E-11,Q869W9,Probable polyketide synthase 16 (dipks16) (EC 2.3.1.-),Probable polyketide synthase 16 (dipks16) (EC 2.3.1.-),GO:0055114; GO:0016491; GO:0019953; GO:0016747,"oxidation-reduction process; oxidoreductase activity; sexual reproduction; transferase activity, transferring acyl groups other than amino-acyl groups",PF00698;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;,,,,,,,,,PKS16_DICDI,Dictyostelium discoideum (Slime mold),sexual reproduction [GO:0019953] comp156709_c0_seq1,289,38.7543,0.46370878,5,0,,4.00E-09,Q8N988,Zinc finger protein 557,Zinc finger protein 557,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13465;,,,,,,,,,ZN557_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp156711_c0_seq1,234,47.4359,0.71744865,5,0,,1.00E-14,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,2.00E-17,CHOYP_HS12B.10.14,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp156713_c0_seq1,231,44.5887,1.22753623,5,0,,9.00E-06,A6QNU9,PI-PLC X domain-containing protein 3,PI-PLC X domain-containing protein 3,GO:0016042; GO:0008081; GO:0004871,lipid catabolic process; phosphoric diester hydrolase activity; signal transducer activity,,,,,,,,,,PLCX3_BOVIN,Bos taurus (Bovine),lipid catabolic process [GO:0016042] comp156737_c0_seq1,282,46.8085,0.45572232,5,0,,2.00E-15,A6QP84,Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter),Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter),GO:0008508; GO:0016021,bile acid:sodium symporter activity; integral to membrane,PF01758;,,,,,,,,,SOAT_BOVIN,Bos taurus (Bovine),sodium-dependent organic anion transport [GO:0043251] comp156757_c0_seq1,333,43.8438,0.06267649,6,2,,5.00E-26,O95876,WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein),WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein),GO:0035085; GO:0060271; GO:0005856; GO:0005886; GO:0016476; GO:0032880; GO:0032185,cilium axoneme; cilium morphogenesis; cytoskeleton; plasma membrane; regulation of embryonic cell shape; regulation of protein localization; septin cytoskeleton organization,PF11768;,,,,,,,,,FRITZ_HUMAN,Homo sapiens (Human),auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cardiovascular system development [GO:0072358]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; glomerular visceral epithelial cell migration [GO:0090521]; kidney development [GO:0001822]; palate development [GO:0060021]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224] comp156762_c0_seq1,249,41.3655,0.37707999,5,0,,4.00E-06,Q8BSV3,BEN domain-containing protein 7,BEN domain-containing protein 7,,,PF10523;,,,,,,,,,BEND7_MOUSE,Mus musculus (Mouse), comp156773_c0_seq1,489,46.4213,1.21132883,10,0,,2.00E-30,Q8R4K8,Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A),Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A),GO:0030154; GO:0004175; GO:0005576; GO:0016020; GO:0046872; GO:0008237; GO:0006508,cell differentiation; endopeptidase activity; extracellular region; membrane; metal ion binding; metallopeptidase activity; proteolysis,PF05572;PF00084;,,,,,,,,,PAPP1_MOUSE,Mus musculus (Mouse), comp156781_c0_seq1,292,33.2192,0,7,0,,8.00E-10,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp156806_c0_seq1,228,38.5965,0.59636564,5,0,,,,,,,,,5.00E-12,CHOYP_KIAA1009.1.1,,,,,,,,, comp156819_c0_seq1,248,45.5645,0.78008787,5,0,,1.00E-15,Q9DC22,DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP),DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP),GO:0080008; GO:0005634; GO:0016567,Cul4-RING ubiquitin ligase complex; nucleus; protein ubiquitination,PF00400;,4.00E-20,CHOYP_DCAF6.2.2,,,,,,,DCAF6_MOUSE,Mus musculus (Mouse),positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ubiquitination [GO:0016567] comp156832_c0_seq1,228,41.6667,0.30863127,5,0,,6.00E-08,Q8BMN4,Leishmanolysin-like peptidase (EC 3.4.24.-),Leishmanolysin-like peptidase (EC 3.4.24.-),GO:0007155; GO:0051301; GO:0005811; GO:0016020; GO:0046872; GO:0004222; GO:0007067; GO:0006508,cell adhesion; cell division; lipid particle; membrane; metal ion binding; metalloendopeptidase activity; mitosis; proteolysis,PF01457;,,,,,,,,,LMLN_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067] comp156839_c0_seq1,244,34.0164,0.57110516,5,0,,3.00E-24,A0JNW5,UHRF1-binding protein 1-like,UHRF1-binding protein 1-like,,,PF12624;,3.00E-27,CHOYP_LOC101159151.1.1,,,,,,,UH1BL_HUMAN,Homo sapiens (Human), comp156866_c0_seq1,203,58.6207,0.69389439,4,0,,4.00E-40,P46791,40S ribosomal protein S2 (Fragment),40S ribosomal protein S2 (Fragment),GO:0003723; GO:0015935; GO:0003735; GO:0006412,RNA binding; small ribosomal subunit; structural constituent of ribosome; translation,PF00333;PF03719;,1.00E-44,CHOYP_RS2.5.10,8.00E-32,ruditapes_c226,,,,,RS2_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),translation [GO:0006412] comp156898_c0_seq1,223,45.7399,0.43127552,1,4,,3.00E-14,Q9GZT4,Serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase),Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17),GO:0005524; GO:0008721; GO:0070179; GO:0003941; GO:0006563; GO:0007568; GO:0045177; GO:0007420; GO:0005509; GO:0005737; GO:0016594; GO:0000287; GO:0043025; GO:0005886; GO:0042803; GO:0051289; GO:0030170; GO:0042866; GO:0042493; GO:0032496; GO:0043278; GO:0030378; GO:0018114,ATP binding; D-serine ammonia-lyase activity; D-serine biosynthetic process; L-serine ammonia-lyase activity; L-serine metabolic process; aging; apical part of cell; brain development; calcium ion binding; cytoplasm; glycine binding; magnesium ion binding; neuronal cell body; plasma membrane; protein homodimerization activity; protein homotetramerization; pyridoxal phosphate binding; pyruvate biosynthetic process; response to drug; response to lipopolysaccharide; response to morphine; serine racemase activity; threonine racemase activity,PF00291;,,,,,,,,,SRR_HUMAN,Homo sapiens (Human),aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; serine family amino acid metabolic process [GO:0009069] comp156911_c0_seq1,203,60.5911,1.45872184,0,5,,3.00E-17,P75436,Putative type I restriction enzyme MpnORFDP M protein (M.MpnORFDP) (EC 2.1.1.72),Putative type I restriction enzyme MpnORFDP M protein (M.MpnORFDP) (EC 2.1.1.72),GO:0003677; GO:0009307; GO:0008170; GO:0009007,DNA binding; DNA restriction-modification system; N-methyltransferase activity; site-specific DNA-methyltransferase (adenine-specific) activity,PF12161;PF02384;,,,,,,,,,T1MD_MYCPN,Mycoplasma pneumoniae (strain ATCC 29342 / M129),DNA restriction-modification system [GO:0009307] comp156964_c0_seq1,292,39.726,0.61261172,2,1,,2.00E-06,Q9VIQ9,Protein sickie,Protein sickie,GO:0005524; GO:0050829; GO:0045087; GO:0017111,ATP binding; defense response to Gram-negative bacterium; innate immune response; nucleoside-triphosphatase activity,PF00004;PF00307;,,,,,,,,,SICK_DROME,Drosophila melanogaster (Fruit fly),actin filament organization [GO:0007015]; axonogenesis [GO:0007409]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response [GO:0045087]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602] comp156978_c0_seq1,274,40.146,0.4772712,7,0,,6.00E-11,Q9UW02,Thioredoxin (Trx) (allergen Cop c 2),Thioredoxin (Trx) (allergen Cop c 2),GO:0045454; GO:0006662; GO:0015035,cell redox homeostasis; glycerol ether metabolic process; protein disulfide oxidoreductase activity,PF00085;,,,,,,,,,THIO_COPCM,Coprinus comatus (Shaggy mane),cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662] comp156987_c0_seq1,206,43.2039,0.22139559,0,2,,1.00E-06,Q3UYK3,TBC1 domain family member 9,TBC1 domain family member 9,GO:0005097; GO:0005509; GO:0032851,Rab GTPase activator activity; calcium ion binding; positive regulation of Rab GTPase activity,PF02893;PF00566;,,,,,,,,,TBCD9_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp156999_c0_seq1,218,45.4128,0.35843635,4,0,,9.00E-07,P98163,Putative vitellogenin receptor (Protein yolkless) (YL),Putative vitellogenin receptor (Protein yolkless) (YL),GO:0005509; GO:0030135; GO:0016021; GO:0048477; GO:0005886; GO:0008196,calcium ion binding; coated vesicle; integral to membrane; oogenesis; plasma membrane; vitellogenin receptor activity,PF12662;PF07645;PF00057;PF00058;,,,,,,,,,YL_DROME,Drosophila melanogaster (Fruit fly),oogenesis [GO:0048477]; vitellogenesis [GO:0007296] comp157009_c0_seq1,236,45.7627,0.48833294,6,0,,8.00E-21,Q3V0Q1,"Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)","Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0016567,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; protein ubiquitination,PF07728;PF12780;PF08393;PF03028;,1.00E-25,CHOYP_LOC587136.3.3,,,,,,,DYH12_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018]; protein ubiquitination [GO:0016567] comp15700_c0_seq1,316,35.1266,0.51562,11,0,,3.00E-12,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,3.00E-16,CHOYP_LOC100374064.1.4,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp157019_c0_seq1,280,42.1429,0.65789543,3,0,,5.00E-32,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,5.00E-26,CHOYP_UBR3.1.1,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp157024_c0_seq1,294,50.6803,0.42538344,8,0,,,,,,,,,9.00E-17,CHOYP_LOC100929680.1.2,,,,,,,,, comp157036_c0_seq1,221,41.629,0.79816734,7,8,,5.00E-21,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp157048_c0_seq1,255,32.549,0.29837289,4,2,,,,,,,,,,,4.00E-12,ruditapes_c21327,,,,,,, comp157082_c0_seq1,215,43.7209,0.39184521,4,0,,1.00E-23,Q9P959,"Alternative oxidase, mitochondrial (EC 1.-.-.-)","Alternative oxidase, mitochondrial (EC 1.-.-.-)",GO:0009916; GO:0016021; GO:0046872; GO:0005743; GO:0005739; GO:0070469,alternative oxidase activity; integral to membrane; metal ion binding; mitochondrial inner membrane; mitochondrion; respiratory chain,PF01786;,,,,,,,,,AOX_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans), comp157083_c0_seq1,214,41.1215,0.66771644,1,3,,5.00E-19,P56373,P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor),P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor),GO:0005524; GO:0005794; GO:0048266; GO:0043197; GO:0004931; GO:0005887; GO:0045121; GO:0007274; GO:0043025; GO:0030432; GO:0010524; GO:0050850; GO:0051260; GO:0001614; GO:0019228; GO:0048167; GO:0033198; GO:0009743; GO:0009409; GO:0009408; GO:0001666; GO:0005791; GO:0050909; GO:0043195; GO:0014832,ATP binding; Golgi apparatus; behavioral response to pain; dendritic spine; extracellular ATP-gated cation channel activity; integral to plasma membrane; membrane raft; neuromuscular synaptic transmission; neuronal cell body; peristalsis; positive regulation of calcium ion transport into cytosol; positive regulation of calcium-mediated signaling; protein homooligomerization; purinergic nucleotide receptor activity; regulation of action potential in neuron; regulation of synaptic plasticity; response to ATP; response to carbohydrate stimulus; response to cold; response to heat; response to hypoxia; rough endoplasmic reticulum; sensory perception of taste; terminal bouton; urinary bladder smooth muscle contraction,PF00864;,,,,,,,,,P2RX3_HUMAN,Homo sapiens (Human),behavioral response to formalin induced pain [GO:0061368]; blood coagulation [GO:0007596]; neuromuscular synaptic transmission [GO:0007274]; neuronal action potential [GO:0019228]; peristalsis [GO:0030432]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of sensory perception of pain [GO:1904058]; protein homooligomerization [GO:0051260]; regulation of synaptic plasticity [GO:0048167]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; sensory perception of taste [GO:0050909]; signal transduction [GO:0007165]; transport [GO:0006810]; urinary bladder smooth muscle contraction [GO:0014832] comp157103_c0_seq1,224,50.4464,0.80306597,1,3,,4.00E-30,Q06442,Protein Wnt-5a,Protein Wnt-5a,GO:0016055; GO:0007275; GO:0005578,Wnt receptor signaling pathway; multicellular organismal development; proteinaceous extracellular matrix,PF00110;,,,,,,,,,WNT5A_AMBME,Ambystoma mexicanum (Axolotl),multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp157105_c0_seq1,266,45.1128,0.33375472,6,0,,,,,,,,,3.00E-16,CHOYP_BRAFLDRAFT_128799.1.1,,,,,,,,, comp157142_c0_seq1,213,61.5023,1.04904273,0,3,,3.00E-07,B8N2I5,Probable beta-galactosidase C (EC 3.2.1.23) (Lactase C),Probable beta-galactosidase C (EC 3.2.1.23) (Lactase C),GO:0004565; GO:0005576; GO:0000272,beta-galactosidase activity; extracellular region; polysaccharide catabolic process,PF10435;PF13363;PF13364;PF01301;,,,,,,,,,BGALC_ASPFN,Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167),polysaccharide catabolic process [GO:0000272] comp157143_c0_seq1,384,42.7083,0.51910464,5,4,,1.00E-32,Q9Z1T6,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235),GO:0000285; GO:0016308; GO:0052810; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0030659; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0032288; GO:0048471; GO:0012506; GO:0008270,1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; myelin assembly; perinuclear region of cytoplasm; vesicle membrane; zinc ion binding,PF00118;PF00610;PF01363;PF01504;,3.00E-12,CHOYP_FYV1.1.1,,,,,,,FYV1_MOUSE,Mus musculus (Mouse),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp157146_c0_seq1,203,50.2463,0.5492441,4,0,,7.00E-08,Q8NFP4,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,,,,,,,,,MDGA1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp157148_c0_seq1,208,44.7115,0.29082305,3,0,,2.00E-07,Q7TSH8,Uncharacterized protein KIAA0195,Transmembrane protein 94,GO:0016021,integral to membrane,,,,,,,,,,K0195_MOUSE,Mus musculus (Mouse), comp157179_c0_seq1,312,43.2692,0.56320866,6,0,,2.00E-17,Q293P8,Cryptochrome-1,Cryptochrome-1,GO:0003913; GO:0006281; GO:0009882; GO:0005737; GO:0050660; GO:0045892; GO:0005641; GO:0048471; GO:0000060; GO:0018298; GO:0042752; GO:0048511; GO:0006351,"DNA photolyase activity; DNA repair; blue light photoreceptor activity; cytoplasm; flavin adenine dinucleotide binding; negative regulation of transcription, DNA-dependent; nuclear envelope lumen; perinuclear region of cytoplasm; protein import into nucleus, translocation; protein-chromophore linkage; regulation of circadian rhythm; rhythmic process; transcription, DNA-dependent",PF00875;PF03441;,4.00E-22,CHOYP_CRY1.1.2,,,,,,,CRY1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),"negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; protein import into nucleus, translocation [GO:0000060]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp157187_c0_seq1,252,41.6667,0.36720462,5,0,,1.00E-10,O15118,Niemann-Pick C1 protein,Niemann-Pick C1 protein,GO:0005794; GO:0007628; GO:0006914; GO:0008206; GO:0071404; GO:0071383; GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0006897; GO:0005783; GO:0005576; GO:0008158; GO:0005887; GO:0031902; GO:0005765; GO:0007041; GO:0045121; GO:0016242; GO:0005635; GO:0048471; GO:0006486; GO:0042493; GO:0015248; GO:0004888; GO:0031982,Golgi apparatus; adult walking behavior; autophagy; bile acid metabolic process; cellular response to low-density lipoprotein particle stimulus; cellular response to steroid hormone stimulus; cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; endocytosis; endoplasmic reticulum; extracellular region; hedgehog receptor activity; integral to plasma membrane; late endosome membrane; lysosomal membrane; lysosomal transport; membrane raft; negative regulation of macroautophagy; nuclear envelope; perinuclear region of cytoplasm; protein glycosylation; response to drug; sterol transporter activity; transmembrane signaling receptor activity; vesicle,PF16414;PF02460;PF12349;,,,,,,,,,NPC1_HUMAN,Homo sapiens (Human),adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; lysosomal transport [GO:0007041]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; positive regulation of cholesterol homeostasis [GO:2000189]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; viral entry into host cell [GO:0046718] comp157250_c0_seq1,235,43.4043,1.03017738,2,4,,1.00E-16,Q6B9X6,Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),GO:0005524; GO:0005516; GO:0031164; GO:0000331; GO:0005829; GO:0000281; GO:0031038; GO:0018209; GO:0018107; GO:0048471; GO:0004674; GO:0031156; GO:0031288,ATP binding; calmodulin binding; contractile vacuolar membrane; contractile vacuole; cytosol; mitotic cytokinesis; myosin II filament organization; peptidyl-serine modification; peptidyl-threonine phosphorylation; perinuclear region of cytoplasm; protein serine/threonine kinase activity; regulation of sorocarp development; sorocarp morphogenesis,PF02816;,,,4.00E-17,ruditapes_c7830,,,,,VWKA_DICDI,Dictyostelium discoideum (Slime mold),contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288] comp157258_c0_seq1,210,45.2381,0.56874605,5,0,,3.00E-07,Q8N4B1,Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A),Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A),GO:0005794; GO:0030136; GO:0005769; GO:0007032; GO:0005543; GO:0001881; GO:0055037; GO:0042147; GO:0005802,"Golgi apparatus; clathrin-coated vesicle; early endosome; endosome organization; phospholipid binding; receptor recycling; recycling endosome; retrograde transport, endosome to Golgi; trans-Golgi network",PF00169;,,,,,,,,,SESQ1_HUMAN,Homo sapiens (Human),"endosome organization [GO:0007032]; receptor recycling [GO:0001881]; retrograde transport, endosome to Golgi [GO:0042147]" comp157259_c0_seq1,249,47.3896,0.53747796,2,2,,,,,,,,,3.00E-28,CHOYP_LOC594379.1.1,,,,,,,,, comp157291_c0_seq1,204,43.1373,0.84888168,2,2,,2.00E-19,P22001,Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3),Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3),GO:0005251; GO:0045121; GO:0015271; GO:0051260; GO:0007268; GO:0008076,delayed rectifier potassium channel activity; membrane raft; outward rectifier potassium channel activity; protein homooligomerization; synaptic transmission; voltage-gated potassium channel complex,PF02214;PF00520;,,,,,,,,,KCNA3_HUMAN,Homo sapiens (Human),potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260] comp157301_c0_seq1,243,42.7984,0.5432374,2,2,,5.00E-11,O14522,Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho),Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho),GO:0045294; GO:0009986; GO:0045295; GO:0007156; GO:0016021; GO:0005886; GO:0004725; GO:0016790; GO:0007169,alpha-catenin binding; cell surface; gamma-catenin binding; homophilic cell adhesion; integral to membrane; plasma membrane; protein tyrosine phosphatase activity; thiolester hydrolase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF00629;PF00102;,,,,,,,,,PTPRT_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp157321_c0_seq1,348,45.6897,0.39213807,6,0,,6.00E-44,Q9GL59,Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase),Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase),GO:0005789; GO:0008488; GO:0016021; GO:0017187,endoplasmic reticulum membrane; gamma-glutamyl carboxylase activity; integral to membrane; peptidyl-glutamic acid carboxylation,PF05090;,,,,,,,,,VKGC_SHEEP,Ovis aries (Sheep),peptidyl-glutamic acid carboxylation [GO:0017187] comp157342_c0_seq1,272,41.9118,0.9288712,3,0,,3.00E-17,Q9NXG6,Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),GO:0031418; GO:0005509; GO:0005789; GO:0016021; GO:0005506; GO:0016706,"L-ascorbic acid binding; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13640;PF13499;,,,,,,,,,P4HTM_HUMAN,Homo sapiens (Human),regulation of erythrocyte differentiation [GO:0045646] comp157360_c0_seq1,262,45.4198,1.06726192,4,2,,5.00E-16,Q07075,Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),GO:0001525; GO:0002005; GO:0002003; GO:0016324; GO:0005903; GO:0016477; GO:0008283; GO:0007267; GO:0044267; GO:0031410; GO:0009897; GO:0032835; GO:0005887; GO:0005765; GO:0070006; GO:0006508; GO:0008270,angiogenesis; angiotensin catabolic process in blood; angiotensin maturation; apical plasma membrane; brush border; cell migration; cell proliferation; cell-cell signaling; cellular protein metabolic process; cytoplasmic vesicle; external side of plasma membrane; glomerulus development; integral to plasma membrane; lysosomal membrane; metalloaminopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPE_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] comp157397_c0_seq1,273,58.9744,0.9305466,0,3,,8.00E-06,O67781,Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A),Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A),GO:0004069; GO:0080130; GO:0009058; GO:0005737; GO:0030170,L-aspartate:2-oxoglutarate aminotransferase activity; L-phenylalanine:2-oxoglutarate aminotransferase activity; biosynthetic process; cytoplasm; pyridoxal phosphate binding,PF00155;,,,,,,,,,AAT_AQUAE,Aquifex aeolicus (strain VF5),biosynthetic process [GO:0009058] comp157451_c0_seq1,234,41.0256,0.81740623,6,0,,9.00E-09,P13686,Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),GO:0003993; GO:0060349; GO:0045453; GO:0005829; GO:0050830; GO:0008199; GO:0008198; GO:0016021; GO:0005764; GO:0050728; GO:0032691; GO:0032695; GO:0045019; GO:0032929; GO:0032720; GO:0034097; GO:0032496; GO:0006771,acid phosphatase activity; bone morphogenesis; bone resorption; cytosol; defense response to Gram-positive bacterium; ferric iron binding; ferrous iron binding; integral to membrane; lysosome; negative regulation of inflammatory response; negative regulation of interleukin-1 beta production; negative regulation of interleukin-12 production; negative regulation of nitric oxide biosynthetic process; negative regulation of superoxide anion generation; negative regulation of tumor necrosis factor production; response to cytokine stimulus; response to lipopolysaccharide; riboflavin metabolic process,PF00149;,,,,,,,,,PPA5_HUMAN,Homo sapiens (Human),bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell adhesion [GO:0007162]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of cell migration [GO:0030335]; response to cholesterol [GO:0070723]; response to cytokine [GO:0034097]; response to L-ascorbic acid [GO:0033591]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; riboflavin metabolic process [GO:0006771] comp157526_c0_seq1,357,48.1793,0.33901781,6,1,,6.00E-37,Q03720,Calcium-activated potassium channel slowpoke (dSlo) (BK channel) (Maxi K channel) (MaxiK),Calcium-activated potassium channel slowpoke (dSlo) (BK channel) (Maxi K channel) (MaxiK),GO:0048512; GO:0060072; GO:0045433; GO:0043005; GO:0043025; GO:0042493; GO:0005249; GO:0008076,"circadian behavior; large conductance calcium-activated potassium channel activity; male courtship behavior, veined wing generated song production; neuron projection; neuronal cell body; response to drug; voltage-gated potassium channel activity; voltage-gated potassium channel complex",PF03493;PF00520;,,,,,,,,,SLO_DROME,Drosophila melanogaster (Fruit fly),"circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; male courtship behavior, veined wing generated song production [GO:0045433]; negative regulation of neuromuscular synaptic transmission [GO:1900074]; potassium ion transport [GO:0006813]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to drug [GO:0042493]" comp157559_c0_seq1,270,36.2963,0.68753586,5,0,,2.00E-06,Q9WUD2,Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Stretch-activated channel 2B) (Vanilloid receptor-like protein 1) (VRL-1),Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Stretch-activated channel 2B) (Vanilloid receptor-like protein 1) (VRL-1),GO:0044295; GO:0005262; GO:0044297; GO:0009986; GO:0012505; GO:0032584; GO:0016021; GO:0042470; GO:0005886; GO:0045773; GO:0090280; GO:0009408,axonal growth cone; calcium channel activity; cell body; cell surface; endomembrane system; growth cone membrane; integral to membrane; melanosome; plasma membrane; positive regulation of axon extension; positive regulation of calcium ion import; response to heat,PF12796;PF00520;,,,,,,,,,TRPV2_RAT,Rattus norvegicus (Rat),negative regulation of cell proliferation [GO:0008285]; response to heat [GO:0009408] comp157564_c0_seq1,325,43.3846,0.40852517,5,1,,2.00E-15,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp157571_c0_seq1,299,48.1605,0.69565996,5,0,,6.00E-14,Q9JIL5,Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF07525;PF01167;,,,,,,,,,TULP4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567] comp157607_c0_seq1,210,35.7143,0.613386,2,0,,,,,,,,,3.00E-14,CHOYP_LOC100496973.5.8,,,,,,,,, comp157617_c0_seq1,270,35.9259,0.35658384,5,1,,7.00E-14,Q8BZW8,NHL repeat-containing protein 2,NHL repeat-containing protein 2,,,PF01436;PF13905;,,,,,,,,,NHLC2_MOUSE,Mus musculus (Mouse), comp157622_c0_seq1,205,44.878,0.30655491,3,1,,9.00E-26,Q3SWY9,Ras-related protein Rab-28,Ras-related protein Rab-28,GO:0019003; GO:0005525; GO:0035253; GO:0036064; GO:0005886; GO:0007264,GDP binding; GTP binding; ciliary rootlet; cilium basal body; plasma membrane; small GTPase mediated signal transduction,PF00071;,1.00E-25,CHOYP_LOC100366300.1.1,,,,,,,RAB28_BOVIN,Bos taurus (Bovine),small GTPase mediated signal transduction [GO:0007264]; toxin transport [GO:1901998] comp157631_c0_seq1,208,44.7115,0.38776406,5,0,,2.00E-13,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp157641_c0_seq1,236,41.5254,0.55245747,5,0,,1.00E-22,Q5F3L1,Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1),Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0043990; GO:0043987; GO:0043988; GO:0070498; GO:0007243; GO:0000287; GO:0045892; GO:0005634; GO:0051092; GO:0035066; GO:0033129; GO:0045944; GO:0004674; GO:0009605; GO:0006950,"ATP binding; cytoplasm; histone H2A-S1 phosphorylation; histone H3-S10 phosphorylation; histone H3-S28 phosphorylation; interleukin-1-mediated signaling pathway; intracellular protein kinase cascade; magnesium ion binding; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of histone acetylation; positive regulation of histone phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; response to external stimulus; response to stress",PF00069;PF00433;,,,,,,,,,KS6A5_CHICK,Gallus gallus (Chicken),histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; intracellular signal transduction [GO:0035556]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp157658_c0_seq1,206,39.8058,0.99521576,1,3,,,,,,,,,,,2.00E-15,ruditapes_c16421,,,,,,, comp15765_c0_seq1,514,45.3307,0.571547,11,4,,3.00E-27,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,6.00E-16,CHOYP_LOC580670.1.6,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp157664_c0_seq1,213,46.9484,0.51879931,3,0,,3.00E-21,Q29AK2,Leishmanolysin-like peptidase (EC 3.4.24.-),Leishmanolysin-like peptidase (EC 3.4.24.-),GO:0007420; GO:0007155; GO:0051301; GO:0051298; GO:0006338; GO:0005737; GO:0008354; GO:0008406; GO:0007444; GO:0016020; GO:0046872; GO:0004222; GO:0007100; GO:0007076; GO:0007052; GO:0008233; GO:0045842; GO:0006508,brain development; cell adhesion; cell division; centrosome duplication; chromatin remodeling; cytoplasm; germ cell migration; gonad development; imaginal disc development; membrane; metal ion binding; metalloendopeptidase activity; mitotic centrosome separation; mitotic chromosome condensation; mitotic spindle organization; peptidase activity; positive regulation of mitotic metaphase/anaphase transition; proteolysis,PF01457;,5.00E-12,CHOYP_LMLN.1.1,,,,,,,LMLN_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842] comp157671_c0_seq1,248,45.1613,0.49210286,3,0,,4.00E-16,Q62059,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0007507; GO:0005540; GO:0005578; GO:0001657,calcium ion binding; carbohydrate binding; cell adhesion; heart development; hyaluronic acid binding; proteinaceous extracellular matrix; ureteric bud development,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; glial cell migration [GO:0008347]; heart development [GO:0007507]; osteoblast differentiation [GO:0001649]; regulation of phosphoprotein phosphatase activity [GO:0043666]; skeletal system development [GO:0001501]; ureteric bud development [GO:0001657] comp157688_c0_seq1,423,47.0449,0.77106917,9,0,,3.00E-14,Q24306,Apoptosis 1 inhibitor (EC 6.3.2.-) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (dIAP1) (Protein thread),Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread),GO:0019788; GO:0016055; GO:0048800; GO:0007298; GO:0008407; GO:0004869; GO:0005737; GO:0008354; GO:0097340; GO:1990001; GO:0043066; GO:0046673; GO:0005634; GO:0090263; GO:0031398; GO:0042787; GO:0045035; GO:0007289; GO:0004842; GO:0008270,NEDD8 ligase activity; Wnt receptor signaling pathway; antennal morphogenesis; border follicle cell migration; chaeta morphogenesis; cysteine-type endopeptidase inhibitor activity; cytoplasm; germ cell migration; inhibition of cysteine-type endopeptidase activity; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of compound eye retinal cell programmed cell death; nucleus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sensory organ precursor cell division; spermatid nucleus differentiation; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,,,,,,,IAP1_DROME,Drosophila melanogaster (Fruit fly),antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055] comp157697_c0_seq1,234,45.7265,0.74683567,5,0,,5.00E-28,Q5JWR5,Protein dopey-1,Protein dopey-1,GO:0015031,protein transport,PF04118;,6.00E-24,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP1_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp157717_c0_seq1,201,41.2935,0.47087413,4,0,,1.00E-06,Q80ZE5,Membrane progestin receptor beta (mPR beta) (Progestin and adipoQ receptor family member VIII),Membrane progestin receptor beta (mPR beta) (Progestin and adipoQ receptor family member VIII),GO:0030154; GO:0016021; GO:0007275; GO:0048477; GO:0005886; GO:0005496,cell differentiation; integral to membrane; multicellular organismal development; oogenesis; plasma membrane; steroid binding,PF03006;,,,,,,,,,MPRB_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; oogenesis [GO:0048477]; response to steroid hormone [GO:0048545] comp157719_c0_seq1,260,43.4615,0.51581791,4,0,,3.00E-13,Q8NB59,Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV),Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV),GO:0008219; GO:0016021; GO:0005543,cell death; integral to membrane; phospholipid binding,PF00168;,3.00E-28,CHOYP_LOC100369472.2.2,,,,,,,SYT14_HUMAN,Homo sapiens (Human),vesicle fusion [GO:0006906] comp157721_c0_seq1,254,44.8819,0.82126877,3,0,,5.00E-08,Q99KC8,von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog),von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog),,,PF08487;PF13768;,,,,,,,,,VMA5A_MOUSE,Mus musculus (Mouse), comp157734_c0_seq1,227,48.0176,0.53738417,5,0,,7.00E-06,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp157755_c0_seq1,217,46.5438,1.28238017,5,0,,4.00E-07,Q5R9W5,WW domain-containing oxidoreductase (EC 1.1.1.-),WW domain-containing oxidoreductase (EC 1.1.1.-),GO:0016055; GO:0006915; GO:0005737; GO:0005739; GO:0030178; GO:0005634; GO:0016491,Wnt receptor signaling pathway; apoptotic process; cytoplasm; mitochondrion; negative regulation of Wnt receptor signaling pathway; nucleus; oxidoreductase activity,PF00106;PF00397;,,,,,,,,,WWOX_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),apoptotic process [GO:0006915]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp157787_c0_seq1,230,45.6522,0.5164032,5,0,,1.00E-12,Q54KD0,TPR repeat-containing protein DDB_G0287407,TPR repeat-containing protein DDB_G0287407,GO:0017111; GO:0000166,nucleoside-triphosphatase activity; nucleotide binding,PF13271;,5.00E-25,CHOYP_TRIADDRAFT_59003.1.1,,,,,,,Y7407_DICDI,Dictyostelium discoideum (Slime mold), comp157789_c0_seq1,353,44.1926,0.40837506,6,0,,4.00E-11,Q6ZQK0,Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3),Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3),GO:0051301; GO:0042585; GO:0007076; GO:0000799,cell division; germinal vesicle; mitotic chromosome condensation; nuclear condensin complex,PF12717;,,,,,,,,,CNDD3_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076] comp157806_c0_seq1,231,41.1255,0.72372123,4,0,,1.00E-17,Q6P2S7,Tetratricopeptide repeat protein GNN (TPR repeat protein GNN) (Grp94-neighboring nucleotidase),Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase),GO:0005737,cytoplasm,PF13271;,,,,,,,,,GNN_HUMAN,Homo sapiens (Human), comp157816_c0_seq1,219,33.3333,0.16667014,3,0,,,,,,,,,,,9.00E-13,ruditapes2_c1163,,,,,,, comp157834_c0_seq1,253,45.4545,0.23260437,1,0,,7.00E-09,Q5REW9,Ankyrin repeat domain-containing protein 27,Ankyrin repeat domain-containing protein 27,GO:0005096; GO:0005737; GO:0043547,GTPase activator activity; cytoplasm; positive regulation of GTPase activity,PF12796;PF02204;,,,,,,,,,ANR27_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp157845_c0_seq1,234,34.6154,0.75807836,6,0,,7.00E-08,Q8CII0,Zinc finger and BTB domain-containing protein 8B,Zinc finger and BTB domain-containing protein 8B,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT8B_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp157932_c0_seq1,230,40,0.5675783,1,2,,8.00E-20,Q15126,Phosphomevalonate kinase (PMKase) (hPMK) (EC 2.7.4.2),Phosphomevalonate kinase (PMKase) (hPMK) (EC 2.7.4.2),GO:0005524; GO:0006695; GO:0005829; GO:0019287; GO:0005777; GO:0004631; GO:0070723,"ATP binding; cholesterol biosynthetic process; cytosol; isopentenyl diphosphate biosynthetic process, mevalonate pathway; peroxisome; phosphomevalonate kinase activity; response to cholesterol",PF04275;,,,,,,,,,PMVK_HUMAN,Homo sapiens (Human),"cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; response to cholesterol [GO:0070723]; sterol biosynthetic process [GO:0016126]" comp157935_c0_seq1,238,45.3782,0.24801545,5,0,,2.00E-09,Q8TBP0,TBC1 domain family member 16,TBC1 domain family member 16,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,4.00E-13,CHOYP_LOC100374096.1.1,,,,,,,TBC16_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of receptor recycling [GO:0001919]; regulation of vesicle fusion [GO:0031338] comp157948_c0_seq1,244,40.1639,0.51363546,3,0,,3.00E-06,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp157990_c0_seq1,261,46.7433,0.85775069,4,0,,9.00E-11,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp158002_c0_seq1,238,42.437,0.4708515,5,0,,1.00E-25,Q925U4,ER degradation-enhancing alpha-mannosidase-like protein 1,ER degradation-enhancing alpha-mannosidase-like protein 1,GO:0030433; GO:0005509; GO:0030176; GO:0051787; GO:0006986,ER-associated protein catabolic process; calcium ion binding; integral to endoplasmic reticulum membrane; misfolded protein binding; response to unfolded protein,PF01532;,2.00E-17,CHOYP_EDEM1.1.1,,,,,,,EDEM1_MOUSE,Mus musculus (Mouse),"endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on C branch [GO:0036510]" comp158005_c0_seq1,216,37.963,1.31041456,2,0,,7.00E-11,Q866A2,Neuronal acetylcholine receptor subunit alpha-7,Neuronal acetylcholine receptor subunit alpha-7,GO:0042113; GO:0042110; GO:0042166; GO:0015464; GO:0004889; GO:0005892; GO:0000187; GO:0016324; GO:0008306; GO:0048149; GO:0035095; GO:0001540; GO:0006816; GO:0030054; GO:0006874; GO:0017081; GO:0050890; GO:0006897; GO:0009897; GO:0060112; GO:0007613; GO:0050728; GO:0032691; GO:0032715; GO:0032720; GO:0045766; GO:0008284; GO:0001988; GO:0045211; GO:0042803; GO:0042391; GO:0014061; GO:0032225; GO:0032094; GO:0001666; GO:0035094; GO:0030317; GO:0007271; GO:0015643,"B cell activation; T cell activation; acetylcholine binding; acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; activation of MAPK activity; apical plasma membrane; associative learning; behavioral response to ethanol; behavioral response to nicotine; beta-amyloid binding; calcium ion transport; cell junction; cellular calcium ion homeostasis; chloride channel regulator activity; cognition; endocytosis; external side of plasma membrane; generation of ovulation cycle rhythm; memory; negative regulation of inflammatory response; negative regulation of interleukin-1 beta production; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure; postsynaptic membrane; protein homodimerization activity; regulation of membrane potential; regulation of norepinephrine secretion; regulation of synaptic transmission, dopaminergic; response to food; response to hypoxia; response to nicotine; sperm motility; synaptic transmission, cholinergic; toxic substance binding",PF02931;PF02932;,,,,,,,,,ACHA7_MACMU,Macaca mulatta (Rhesus macaque),"activation of MAPK activity [GO:0000187]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; endocytosis [GO:0006897]; generation of ovulation cycle rhythm [GO:0060112]; memory [GO:0007613]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; regulation of membrane potential [GO:0042391]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; sperm motility [GO:0030317]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110]" comp158024_c0_seq1,228,44.7368,0.79515419,3,0,,,,,,,,,1.00E-13,CHOYP_LOC579367.1.1,,,,,,,,, comp158038_c0_seq1,228,68.4211,1.09318975,0,5,,1.00E-15,P59715,Putative cardiolipin synthase YbhO (CL synthase) (EC 2.7.8.-),Cardiolipin synthase B (CL synthase) (EC 2.7.8.-),GO:0008654; GO:0005886; GO:0016740,phospholipid biosynthetic process; plasma membrane; transferase activity,PF13091;,,,,,,,,,YBHO_SHIFL,Shigella flexneri,cardiolipin biosynthetic process [GO:0032049] comp158062_c0_seq1,205,33.1707,0.73573179,3,0,,5.00E-09,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp158063_c0_seq1,299,45.1505,0.73892452,4,0,,4.00E-07,A7J1T2,Mitogen-activated protein kinase kinase kinase 13-A (EC 2.7.11.25),Mitogen-activated protein kinase kinase kinase 13-A (EC 2.7.11.25),GO:0005524; GO:0004709; GO:0000165; GO:0005737; GO:0016020; GO:0046777,ATP binding; MAP kinase kinase kinase activity; MAPK cascade; cytoplasm; membrane; protein autophosphorylation,PF07714;,7.00E-31,CHOYP_LOC590385.1.1,,,,,,,M313A_XENLA,Xenopus laevis (African clawed frog),JNK cascade [GO:0007254]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777] comp158073_c0_seq1,337,41.543,0.80633978,5,2,,2.00E-22,Q9I9R3,Solute carrier family 40 member 1 (Ferroportin-1),Solute carrier family 40 member 1 (Ferroportin-1),GO:0035162; GO:0042541; GO:0016021; GO:0055072; GO:0005381; GO:0043362; GO:0046688; GO:0010039,embryonic hemopoiesis; hemoglobin biosynthetic process; integral to membrane; iron ion homeostasis; iron ion transmembrane transporter activity; nucleate erythrocyte maturation; response to copper ion; response to iron ion,PF06963;,,,,,,,,,S40A1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic hemopoiesis [GO:0035162]; hemoglobin biosynthetic process [GO:0042541]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; nucleate erythrocyte maturation [GO:0043362]; response to copper ion [GO:0046688]; response to iron ion [GO:0010039] comp158081_c0_seq1,259,38.9961,0.41107332,2,2,,8.00E-20,A6NDJ8,Putative Rab-43-like protein ENSP00000330714,,GO:0005525; GO:0015031; GO:0007264,GTP binding; protein transport; small GTPase mediated signal transduction,,7.00E-11,CHOYP_LOC100366735.1.1,,,,,,,RB43L_HUMAN,, comp158085_c0_seq1,226,46.0177,0.26152586,3,0,,2.00E-19,Q8BZW8,NHL repeat-containing protein 2,NHL repeat-containing protein 2,,,PF01436;PF13905;,,,,,,,,,NHLC2_MOUSE,Mus musculus (Mouse), comp158088_c0_seq1,229,38.8646,0.63961175,5,0,,,,,,,,,3.00E-14,CHOYP_LOC100497321.2.4,,,,,,,,, comp158119_c0_seq1,345,38.2609,0.49288163,4,0,,3.00E-08,Q9R0T8,Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i),Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i),GO:0005524; GO:0008384; GO:0004704; GO:0016605; GO:0005737; GO:0008630; GO:0043123,ATP binding; IkappaB kinase activity; NF-kappaB-inducing kinase activity; PML body; cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of I-kappaB kinase/NF-kappaB cascade,PF00069;,,,,,,,,,IKKE_MOUSE,Mus musculus (Mouse),cellular response to virus [GO:0098586]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; response to interferon-beta [GO:0035456]; response to type I interferon [GO:0034340] comp158128_c0_seq1,242,30.5785,1.25722768,5,4,,,,,,,,,,,4.00E-12,ruditapes_c9835,,,,,,, comp158137_c0_seq1,226,43.3628,0.28375556,4,0,,1.00E-11,Q9NQ94,APOBEC1 complementation factor (APOBEC1-stimulating protein),APOBEC1 complementation factor (APOBEC1-stimulating protein),GO:0030895; GO:0016554; GO:0005737; GO:0005783; GO:0010467; GO:0016556; GO:0006397; GO:0005654; GO:0000166; GO:0050821; GO:0003727,apolipoprotein B mRNA editing enzyme complex; cytidine to uridine editing; cytoplasm; endoplasmic reticulum; gene expression; mRNA modification; mRNA processing; nucleoplasm; nucleotide binding; protein stabilization; single-stranded RNA binding,PF00076;,,,,,,,,,A1CF_HUMAN,Homo sapiens (Human),cytidine to uridine editing [GO:0016554]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; protein stabilization [GO:0050821] comp158229_c0_seq1,202,43.0693,0.42964016,3,0,,4.00E-12,Q7TQF2,F-box only protein 10,F-box only protein 10,,,PF12937;PF05048;,,,,,,,,,FBX10_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of apoptotic process [GO:0042981] comp158262_c0_seq1,240,37.0833,1.12735845,5,0,,3.00E-07,Q3UVD5,Leucine-rich repeat-containing G-protein coupled receptor 6,Leucine-rich repeat-containing G-protein coupled receptor 6,GO:0016055; GO:0016021; GO:0005886; GO:0016500,Wnt receptor signaling pathway; integral to membrane; plasma membrane; protein-hormone receptor activity,PF13855;,,,,,,,,,LGR6_MOUSE,Mus musculus (Mouse),positive regulation of cell migration [GO:0030335]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055] comp158285_c0_seq1,250,43.6,0.96540006,5,0,,3.00E-10,P18515,Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2) (Fragment),Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2) (Fragment),GO:0005634; GO:0003708; GO:0043565; GO:0043401; GO:0003707; GO:0008270,nucleus; retinoic acid receptor activity; sequence-specific DNA binding; steroid hormone mediated signaling pathway; steroid hormone receptor activity; zinc ion binding,PF00105;,,,,,,,,,RARB_NOTVI,Notophthalmus viridescens (Eastern newt) (Triturus viridescens),"steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]" comp158291_c0_seq1,460,46.3043,0.62286369,6,0,,1.00E-34,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp158297_c0_seq1,293,48.1229,0.06076962,3,2,,1.00E-08,Q9UGK8,Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein),GO:0005087; GO:0005737; GO:0045111; GO:0050709; GO:0005730; GO:0007165,Ran guanyl-nucleotide exchange factor activity; cytoplasm; intermediate filament cytoskeleton; negative regulation of protein secretion; nucleolus; signal transduction,PF00415;,,,,,,,,,SRGEF_HUMAN,Homo sapiens (Human),negative regulation of protein secretion [GO:0050709]; signal transduction [GO:0007165] comp158352_c0_seq1,239,46.0251,0.9996704,5,0,,1.00E-06,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp158374_c0_seq1,221,41.629,0.95144805,3,0,,3.00E-11,Q0EEE2,Patched domain-containing protein 3 (RND-type protein RNDEu-3),Patched domain-containing protein 3 (RND-type protein RNDEu-3),GO:0008158; GO:0016021,hedgehog receptor activity; integral to membrane,PF02460;,,,,,,,,,PTHD3_MOUSE,Mus musculus (Mouse), comp158436_c0_seq1,252,42.0635,0.18247673,0,5,,3.00E-06,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp158440_c0_seq1,282,44.3262,0.73507418,4,0,,3.00E-27,Q9VN12,Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)-exchange protein CG1090),Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)-exchange protein CG1090),GO:0008273; GO:0016021; GO:0015293,"calcium, potassium:sodium antiporter activity; integral to membrane; symporter activity",PF01699;,3.00E-29,CHOYP_LOC100883998.1.1,,,,,,,NCKXH_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; sodium ion transport [GO:0006814] comp158447_c0_seq1,214,59.8131,1.06253865,0,4,,2.00E-14,P67672,Uncharacterized HTH-type transcriptional regulator Mb1861,Uncharacterized HTH-type transcriptional regulator Mb1861,GO:0003677; GO:0000166; GO:0006355; GO:0006351,"DNA binding; nucleotide binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13411;,,,,,,,,,Y1861_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp158467_c0_seq1,237,45.5696,0.57449299,3,0,,5.00E-18,P28828,Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48),GO:0045296; GO:0005913; GO:0007156; GO:0016021; GO:0030027; GO:0016525; GO:0010596; GO:0001937; GO:0048471; GO:0045909; GO:0042493; GO:0010842; GO:0031290; GO:0005001,cadherin binding; cell-cell adherens junction; homophilic cell adhesion; integral to membrane; lamellipodium; negative regulation of angiogenesis; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; perinuclear region of cytoplasm; positive regulation of vasodilation; response to drug; retina layer formation; retinal ganglion cell axon guidance; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF00047;PF00629;PF00102;,,,,,,,,,PTPRM_MOUSE,Mus musculus (Mouse),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; positive regulation of vasodilation [GO:0045909]; protein dephosphorylation [GO:0006470]; response to drug [GO:0042493]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165] comp158473_c0_seq1,235,43.8298,0.65556743,3,0,,,,,,,,,1.00E-14,CHOYP_TRIADDRAFT_55241.1.1,,,,,,,,, comp158477_c0_seq1,213,43.662,0.50808337,0,3,,6.00E-09,Q13591,Semaphorin-5A (Semaphorin-F) (Sema F),Semaphorin-5A (Semaphorin-F) (Sema F),GO:0007411; GO:0008046; GO:0007155; GO:0007267; GO:0016021; GO:0001569; GO:0005886,axon guidance; axon guidance receptor activity; cell adhesion; cell-cell signaling; integral to membrane; patterning of blood vessels; plasma membrane,PF01403;PF00090;,,,,,,,,,SEM5A_HUMAN,Homo sapiens (Human),axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] comp158493_c0_seq1,331,47.7341,0.90667494,5,0,,3.00E-23,A0JPI9,Uncharacterized protein C14orf166B homolog,Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74),,,PF13516;,9.00E-24,CHOYP_LOC100372392.8.8,,,,,,,CN16B_RAT,Rattus norvegicus (Rat), comp158507_c0_seq1,201,52.2388,0.68193736,3,0,,8.00E-16,A1L0Y5,Septin-2B,Septin-2B,GO:0005525; GO:0051301; GO:0042384; GO:0060170; GO:0032154; GO:0005737; GO:0030496; GO:0007067; GO:0031105; GO:0007224; GO:0005819,GTP binding; cell division; cilium assembly; cilium membrane; cleavage furrow; cytoplasm; midbody; mitosis; septin complex; smoothened signaling pathway; spindle,PF00735;,,,,,,,,,SEP2B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; smoothened signaling pathway [GO:0007224] comp158521_c0_seq1,213,32.8638,0.58153456,3,0,,6.00E-09,Q8I7P9,Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305; GO:0005634; GO:0008233; GO:0006508; GO:0006313,"DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus; peptidase activity; proteolysis; transposition, DNA-mediated",PF00665;PF00078;,,,,,,,,,POL5_DROME,Drosophila melanogaster (Fruit fly),"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp158543_c0_seq1,223,47.5336,0.72702508,4,0,,2.00E-10,Q80TC5,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,2.00E-18,CHOYP_LOC100560153.3.3,,,,,,,POGK_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp158554_c0_seq1,238,60.084,0.89040788,3,0,,8.00E-22,P0A5Z4,DNA-binding response regulator MtrA,,GO:0003677; GO:0005737; GO:0044117; GO:0035556; GO:0046872; GO:0000156; GO:0005886; GO:0045893; GO:0006468; GO:0006351,"DNA binding; cytoplasm; growth of symbiont in host; intracellular signal transduction; metal ion binding; phosphorelay response regulator activity; plasma membrane; positive regulation of transcription, DNA-dependent; protein phosphorylation; transcription, DNA-dependent",,,,,,,,,,MTRA_MYCTU,, comp158562_c0_seq1,219,49.7717,0.67348343,5,0,,2.00E-22,O65353,60S ribosomal protein L5,60S ribosomal protein L5,GO:0008097; GO:0005840; GO:0003735; GO:0006412,5S rRNA binding; ribosome; structural constituent of ribosome; translation,PF14204;PF17144;,3.00E-52,CHOYP_RL5.2.4,2.00E-34,ruditapes_lrc34578,,,,,RL5_HELAN,Helianthus annuus (Common sunflower),translation [GO:0006412] comp158572_c0_seq1,260,46.5385,0.42810912,4,0,,4.00E-09,Q5XK03,Serine incorporator 4,Serine incorporator 4,GO:0016021; GO:0008654,integral to membrane; phospholipid biosynthetic process,PF03348;,2.00E-12,CHOYP_SERC1.1.1,,,,,,,SERC4_MOUSE,Mus musculus (Mouse),phospholipid biosynthetic process [GO:0008654] comp158575_c0_seq1,204,49.0196,0.33012065,2,2,,3.00E-15,Q5ADN9,Palmitoyltransferase PFA3 (EC 2.3.1.225) (Protein fatty acyltransferase 3),Palmitoyltransferase PFA3 (EC 2.3.1.225) (Protein fatty acyltransferase 3),GO:0016021; GO:0016746; GO:0005774; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; vacuolar membrane; zinc ion binding",PF01529;,,,,,,,,,PFA3_CANAL,Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast), comp158580_c0_seq1,215,50.2326,0.74101088,1,2,,6.00E-12,Q9ES88,Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00939;,2.00E-17,CHOYP_S13A2.2.2,,,,,,,S13A2_MOUSE,Mus musculus (Mouse), comp158586_c0_seq1,228,42.1053,0.19887486,3,0,,2.00E-10,Q38SD2,Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1),Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1),GO:0005524; GO:0005525; GO:0046872; GO:0005739; GO:0004674; GO:0007264,ATP binding; GTP binding; metal ion binding; mitochondrion; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF12796;PF16095;PF00069;PF08477;,,,,,,,,,LRRK1_HUMAN,Homo sapiens (Human),bone resorption [GO:0045453]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; small GTPase mediated signal transduction [GO:0007264] comp158605_c0_seq1,213,61.0329,1.17500799,0,4,,1.00E-08,Q7TXK5,Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase),GO:0005524; GO:0071766; GO:0006633; GO:0016874; GO:0008610,ATP binding; Actinobacterium-type cell wall biogenesis; fatty acid biosynthetic process; ligase activity; lipid biosynthetic process,PF00501;,,,,,,,,,FAA29_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),Actinobacterium-type cell wall biogenesis [GO:0071766]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610] comp158622_c0_seq1,208,45.1923,0.67733047,3,0,,2.00E-09,Q96CX3,Zinc finger protein 501 (Zinc finger protein 52),Zinc finger protein 501 (Zinc finger protein 52),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN501_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp158623_c0_seq1,295,38.3051,1.37676001,4,0,,,,,,,,,1.00E-14,CHOYP_TVAG_355490.10.22,,,,,,,,, comp158648_c0_seq1,216,37.037,1.09116104,2,0,,3.00E-07,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp158652_c0_seq1,249,42.9719,0.96088202,4,0,,6.00E-26,P48965,M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A),M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A),GO:0000082; GO:0051301; GO:0005737; GO:0007067; GO:0005634; GO:0035335; GO:0004721; GO:0004725; GO:0009314,G1/S transition of mitotic cell cycle; cell division; cytoplasm; mitosis; nucleus; peptidyl-tyrosine dephosphorylation; phosphoprotein phosphatase activity; protein tyrosine phosphatase activity; response to radiation,PF06617;PF00581;,,,,,,,,,MPIP1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; response to radiation [GO:0009314] comp158656_c0_seq1,216,46.2963,0.78403929,2,2,,1.00E-11,Q99102,Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)],Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)],GO:0005176; GO:0005796; GO:0016266; GO:0007160; GO:0030197; GO:0005887; GO:0043687; GO:0005578,"ErbB-2 class receptor binding; Golgi lumen; O-glycan processing; cell-matrix adhesion; extracellular matrix constituent, lubricant activity; integral to plasma membrane; post-translational protein modification; proteinaceous extracellular matrix",PF06119;PF00094;,,,,,,,,,MUC4_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; maintenance of gastrointestinal epithelium [GO:0030277]; O-glycan processing [GO:0016266] comp158722_c0_seq1,251,51.7928,0.54000857,4,0,,,,,,,,,1.00E-13,CHOYP_CMTA1.2.2,,,,,,,,, comp158736_c0_seq1,270,44.4444,1.09055822,1,2,,4.00E-09,Q8K1C7,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT14_MOUSE,Mus musculus (Mouse), comp158787_c0_seq1,206,43.6893,1.04759554,3,0,,9.00E-17,P17671,"Ecdysone-induced protein 75B, isoforms C/D (E75-A) (Nuclear receptor subfamily 1 group D member 3, isoforms C/D)","Ecdysone-induced protein 75B, isoforms C/D (E75-A) (Nuclear receptor subfamily 1 group D member 3, isoforms C/D)",GO:0003677; GO:0019730; GO:0018990; GO:0035072; GO:0020037; GO:0004879; GO:0005634; GO:0048477; GO:0007553; GO:0043565; GO:0003707; GO:0004887; GO:0008270,"DNA binding; antimicrobial humoral response; ecdysis, chitin-based cuticle; ecdysone-mediated induction of salivary gland cell autophagic cell death; heme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; oogenesis; regulation of ecdysteroid metabolic process; sequence-specific DNA binding; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,1.00E-19,CHOYP_E75BB.1.1,,,,,,,E75BC_DROME,Drosophila melanogaster (Fruit fly),"antimicrobial humoral response [GO:0019730]; ecdysis, chitin-based cuticle [GO:0018990]; molting cycle, chitin-based cuticle [GO:0007591]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; regulation of ecdysteroid metabolic process [GO:0007553]; regulation of gene expression [GO:0010468]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; response to ecdysone [GO:0035075]; transcription, DNA-templated [GO:0006351]" comp158817_c0_seq1,252,41.2698,0.37775884,3,0,,,,,,,,,,,3.00E-13,ruditapes_c12888,,,,,,, comp158828_c0_seq1,231,47.619,0.98411176,4,0,,,,,,,,,,,4.00E-37,ruditapes_c8677,,,,,,, comp158839_c0_seq1,303,39.934,0.49918442,5,0,,4.00E-06,P58215,Lysyl oxidase homolog 3 (EC 1.4.3.-) (Lysyl oxidase-like protein 3),Lysyl oxidase homolog 3 (EC 1.4.3.-) (Lysyl oxidase-like protein 3),GO:0005507; GO:0001837; GO:0005576; GO:0005615; GO:0016020; GO:0045892; GO:0005634; GO:0004720; GO:0005044,"copper ion binding; epithelial to mesenchymal transition; extracellular region; extracellular space; membrane; negative regulation of transcription, DNA-dependent; nucleus; protein-lysine 6-oxidase activity; scavenger receptor activity",PF01186;PF00530;,,,,,,,,,LOXL3_HUMAN,Homo sapiens (Human),"epithelial to mesenchymal transition [GO:0001837]; negative regulation of transcription, DNA-templated [GO:0045892]" comp158854_c0_seq1,205,40,0.3678659,3,0,,2.00E-07,Q967F4,Cadherin-related hmr-1 (Protein Hammerhead),Cadherin-related hmr-1 (Protein Hammerhead),GO:0003384; GO:0005509; GO:0016342; GO:0042074; GO:0005913; GO:0007016; GO:0000132; GO:0007156; GO:0016021; GO:0007399,apical constriction involved in gastrulation; calcium ion binding; catenin complex; cell migration involved in gastrulation; cell-cell adherens junction; cytoskeletal anchoring at plasma membrane; establishment of mitotic spindle orientation; homophilic cell adhesion; integral to membrane; nervous system development,PF00028;PF01049;PF02210;,,,,,,,,,HMR1_CAEEL,Caenorhabditis elegans,apical constriction involved in gastrulation [GO:0003384]; cell migration [GO:0016477]; cell migration involved in gastrulation [GO:0042074]; cytoskeletal anchoring at plasma membrane [GO:0007016]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] comp158868_c0_seq1,212,51.4151,0.36225296,3,0,,6.00E-19,P35440,Thrombospondin-2,Thrombospondin-2,GO:0005604; GO:0005509; GO:0007155; GO:0008201; GO:0016525,basement membrane; calcium ion binding; cell adhesion; heparin binding; negative regulation of angiogenesis,PF12947;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525] comp158875_c0_seq1,207,63.285,0.92381773,0,4,,5.00E-40,Q6A8I8,Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),GO:0005524; GO:0004813; GO:0006419; GO:0005737; GO:0000049; GO:0008270,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytoplasm; tRNA binding; zinc ion binding,PF02272;PF01411;PF07973;,,,,,,,,,SYA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),alanyl-tRNA aminoacylation [GO:0006419] comp158912_c0_seq1,206,41.7476,0.44879106,4,0,,5.00E-08,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp158929_c0_seq1,240,44.5833,0.60122213,3,0,,1.00E-11,Q9WV18,Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1),Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1),GO:0004965; GO:0038039; GO:0007193; GO:0030054; GO:0005737; GO:0030425; GO:0007214; GO:0005887; GO:0045211; GO:0042734,G-protein coupled GABA receptor activity; G-protein coupled receptor heterodimeric complex; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; cell junction; cytoplasm; dendrite; gamma-aminobutyric acid signaling pathway; integral to plasma membrane; postsynaptic membrane; presynaptic membrane,PF00003;PF01094;PF00084;,,,,,,,,,GABR1_MOUSE,Mus musculus (Mouse),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094] comp158945_c0_seq1,257,35.4086,0.74783741,4,0,,,,,,,,,2.00E-11,CHOYP_contig_021369,4.00E-12,ruditapes_lrc31629,,,,,,, comp158964_c0_seq1,217,41.4747,1.18480777,2,0,,1.00E-08,P51690,Arylsulfatase E (ASE) (EC 3.1.6.-),Arylsulfatase E (ASE) (EC 3.1.6.-),GO:0005795; GO:0004065; GO:0005788; GO:0006687; GO:0046872; GO:0043687; GO:0001501; GO:0044281,Golgi stack; arylsulfatase activity; endoplasmic reticulum lumen; glycosphingolipid metabolic process; metal ion binding; post-translational protein modification; skeletal system development; small molecule metabolic process,PF00884;,,,,,,,,,ARSE_HUMAN,Homo sapiens (Human),glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]; skeletal system development [GO:0001501] comp158982_c0_seq1,230,40.4348,0.32505305,0,5,,2.00E-08,Q14643,"Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)","Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)",GO:0038095; GO:0038096; GO:0007202; GO:0005955; GO:0032469; GO:0005789; GO:0006112; GO:0007173; GO:0008543; GO:0045087; GO:0005220; GO:0016021; GO:0005218; GO:0070059; GO:0048011; GO:0005637; GO:0005730; GO:0035091; GO:0030168; GO:0031088; GO:0031095; GO:0009791; GO:0014069; GO:0050796; GO:0051209; GO:0001666; GO:0016529; GO:0044281; GO:0050882,"Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; activation of phospholipase C activity; calcineurin complex; endoplasmic reticulum calcium ion homeostasis; endoplasmic reticulum membrane; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; integral to membrane; intracellular ligand-gated calcium channel activity; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; neurotrophin TRK receptor signaling pathway; nuclear inner membrane; nucleolus; phosphatidylinositol binding; platelet activation; platelet dense granule membrane; platelet dense tubular network membrane; post-embryonic development; postsynaptic density; regulation of insulin secretion; release of sequestered calcium ion into cytosol; response to hypoxia; sarcoplasmic reticulum; small molecule metabolic process; voluntary musculoskeletal movement",PF08709;PF00520;PF02815;PF08454;PF01365;,,,,,,,,,ITPR1_HUMAN,Homo sapiens (Human),calcium ion transport [GO:0006816]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of calcium-mediated signaling [GO:0050849]; platelet activation [GO:0030168]; post-embryonic development [GO:0009791]; regulation of autophagy [GO:0010506]; regulation of cardiac conduction [GO:1903779]; regulation of insulin secretion [GO:0050796]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; voluntary musculoskeletal movement [GO:0050882] comp159001_c0_seq1,227,50.2203,0.50379766,3,0,,2.00E-10,Q709C8,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp159009_c0_seq1,273,39.1941,0.31350535,2,1,,4.00E-43,Q5ZL16,WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B),WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B),GO:0000045; GO:0005737; GO:0080025; GO:0032266,"autophagic vacuole assembly; cytoplasm; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding",,3.00E-41,CHOYP_WIPI3.1.1,,,,,,,WIPI3_CHICK,Gallus gallus (Chicken),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497] comp159036_c0_seq1,221,31.6742,0.74001515,1,0,,,,,,,,,8.00E-16,CHOYP_LOC764672.1.1,,,,,,,,, comp159056_c0_seq1,340,43.8235,0.79874565,5,0,,6.00E-20,P14755,Lambda-crystallin (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),Lambda-crystallin (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH),GO:0003857; GO:0050104; GO:0070403; GO:0005829; GO:0006631; GO:0005212,3-hydroxyacyl-CoA dehydrogenase activity; L-gulonate 3-dehydrogenase activity; NAD+ binding; cytosol; fatty acid metabolic process; structural constituent of eye lens,PF00725;PF02737;,,,9.00E-28,ruditapes_c10043,,,,,CRYL1_RABIT,Oryctolagus cuniculus (Rabbit),fatty acid metabolic process [GO:0006631] comp159087_c0_seq1,208,44.7115,0.39434874,3,0,,1.00E-11,Q7Z407,CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD3_HUMAN,Homo sapiens (Human), comp159089_c0_seq1,213,47.8873,0.76430256,2,0,,4.00E-34,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,8.00E-60,CHOYP_LOC577371.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp159145_c0_seq1,216,62.037,0.93177138,2,1,,9.00E-15,P46836,30S ribosomal protein S1,30S ribosomal protein S1,GO:0003723; GO:0005840; GO:0003735; GO:0006412,RNA binding; ribosome; structural constituent of ribosome; translation,PF00575;,,,,,,,,,RS1_MYCLE,Mycobacterium leprae (strain TN),translation [GO:0006412] comp159203_c0_seq1,229,44.1048,0.27123159,3,0,,1.00E-13,E7FCN8,Protein inturned (Inturned planar cell polarity effector homolog),Protein inturned (Inturned planar cell polarity effector homolog),GO:0009986; GO:0042384; GO:0005737; GO:0060173; GO:0007399; GO:0008589,cell surface; cilium assembly; cytoplasm; limb development; nervous system development; regulation of smoothened signaling pathway,,,,,,,,,,INTU_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; limb development [GO:0060173]; nervous system development [GO:0007399]; regulation of smoothened signaling pathway [GO:0008589] comp159216_c0_seq1,231,45.4545,0.50729814,3,0,,6.00E-24,Q5D1D6,Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1),Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1),GO:0005525; GO:0006184; GO:0003924; GO:0000139; GO:0042742; GO:0051607; GO:0005576,GTP binding; GTP catabolic process; GTPase activity; Golgi membrane; defense response to bacterium; defense response to virus; extracellular region,PF02263;PF02841;,,,,,,,,,GBP1_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607] comp159244_c0_seq1,218,47.2477,0.58069404,2,0,,3.00E-21,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-27,CHOYP_LOC577371.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp159248_c0_seq1,228,38.1579,0.60711666,1,1,,3.00E-09,Q9XWB9,BTB and MATH domain-containing protein 36,BTB and MATH domain-containing protein 36,,,PF00651;PF00917;,,,,,,,,,BAT36_CAEEL,Caenorhabditis elegans, comp159249_c0_seq1,214,33.1776,0.17090993,3,0,,4.00E-11,Q96LW1,Zinc finger protein 354B,Zinc finger protein 354B,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,Z354B_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp159285_c0_seq1,214,36.9159,1.6310701,1,2,,2.00E-08,Q96QE2,Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13),GO:0016021; GO:0005886; GO:0022891; GO:0055085,integral to membrane; plasma membrane; substrate-specific transmembrane transporter activity; transmembrane transport,PF00083;,,,,,,,,,MYCT_HUMAN,Homo sapiens (Human),glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428] comp159292_c0_seq1,267,51.6854,0.17249759,3,0,,,,,,,,,5.00E-13,CHOYP_BRAFLDRAFT_122847.2.2,,,,,,,,, comp159294_c0_seq1,210,43.3333,0.83815207,1,2,,3.00E-10,Q28036,Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1),Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1),GO:0048306; GO:0071468; GO:0005783; GO:0005789; GO:0016021; GO:0005886; GO:0051259; GO:0051453; GO:0001101; GO:0071436; GO:0015385,calcium-dependent protein binding; cellular response to acidity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; plasma membrane; protein oligomerization; regulation of intracellular pH; response to acid; sodium ion export; sodium:hydrogen antiporter activity,PF00999;PF16644;,,,,,,,,,SL9A1_BOVIN,Bos taurus (Bovine),cellular response to acidic pH [GO:0071468]; potassium ion transmembrane transport [GO:0071805]; protein oligomerization [GO:0051259]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; response to acidic pH [GO:0010447]; sodium ion export [GO:0071436]; sodium ion import across plasma membrane [GO:0098719] comp159313_c0_seq1,219,50.2283,0.9163676,3,0,,1.00E-17,Q1PSW8,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:2000637; GO:0051865; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,,,,,,,,,LIN41_MOUSE,Mus musculus (Mouse),3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] comp159327_c0_seq1,212,49.0566,0.94844411,3,0,,2.00E-16,Q6UWW8,Carboxylesterase 3 (EC 3.1.1.1) (Liver carboxylesterase 31 homolog),Carboxylesterase 3 (EC 3.1.1.1) (Liver carboxylesterase 31 homolog),GO:0004091; GO:0005788,carboxylesterase activity; endoplasmic reticulum lumen,PF00135;,,,,,,,,,EST3_HUMAN,Homo sapiens (Human), comp159330_c0_seq1,249,46.988,0.43860357,3,0,,4.00E-39,Q8WPJ2,"Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)","Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)",GO:0046355; GO:0016985,"mannan catabolic process; mannan endo-1,4-beta-mannosidase activity",PF00150;,9.00E-16,CHOYP_MANA.2.3,,,,,,,MANA_MYTED,Mytilus edulis (Blue mussel),mannan catabolic process [GO:0046355] comp159331_c0_seq1,261,49.8084,0.32100447,3,0,,4.00E-47,Q8TFN0,Nucleoside diphosphate kinase (NDP kinase) (EC 2.7.4.6) (AnNDK) (NDK),Nucleoside diphosphate kinase (NDP kinase) (EC 2.7.4.6) (AnNDK) (NDK),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0051211; GO:0005576; GO:0046872; GO:0005739; GO:0004550; GO:0009142,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; anisotropic cell growth; extracellular region; metal ion binding; mitochondrion; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process,PF00334;,4.00E-90,CHOYP_AGAP_AGAP007120.1.1,2.00E-29,ruditapes2_lrc4875,,,,,NDK_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),anisotropic cell growth [GO:0051211]; CDP phosphorylation [GO:0061508]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228] comp159343_c0_seq1,214,46.729,1.04710079,3,0,,1.00E-10,P42916,Collectin-43 (CL-43) (43 kDa collectin),Collectin-43 (CL-43) (43 kDa collectin),GO:0005581; GO:0005537,collagen; mannose binding,PF01391;PF00059;PF09006;,,,,,,,,,CL43_BOVIN,Bos taurus (Bovine), comp159365_c0_seq1,221,40.724,0.4663961,2,0,,2.00E-16,Q9JLU4,SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2),SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2),GO:0030160; GO:0000165; GO:0097114; GO:0097113; GO:0048854; GO:0030054; GO:0060170; GO:0005737; GO:0060997; GO:0097117; GO:0035255; GO:0007612; GO:0035641; GO:0007613; GO:0032232; GO:0045794; GO:0050885; GO:0097481; GO:2000969; GO:0060999; GO:2000463; GO:1900451; GO:0048170; GO:0051835; GO:0051968; GO:0097107; GO:0045211; GO:0051259; GO:0043621; GO:2000822; GO:0061001; GO:2000821; GO:1900452; GO:1900271; GO:0035176; GO:0021773; GO:0071625; GO:0008270,"GKAP/Homer scaffold activity; MAPK cascade; N-methyl-D-aspartate receptor clustering; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering; brain morphogenesis; cell junction; cilium membrane; cytoplasm; dendritic spine morphogenesis; guanylate kinase-associated protein clustering; ionotropic glutamate receptor binding; learning; locomotory exploration behavior; memory; negative regulation of actin filament bundle assembly; negative regulation of cell volume; neuromuscular process controlling balance; neuronal postsynaptic density; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; positive regulation of dendritic spine development; positive regulation of excitatory postsynaptic membrane potential; positive regulation of glutamate receptor signaling pathway; positive regulation of long-term neuronal synaptic plasticity; positive regulation of synapse structural plasticity; positive regulation of synaptic transmission, glutamatergic; postsynaptic density assembly; postsynaptic membrane; protein oligomerization; protein self-association; regulation of behavioral fear response; regulation of dendritic spine morphogenesis; regulation of grooming behavior; regulation of long term synaptic depression; regulation of long-term synaptic potentiation; social behavior; striatal medium spiny neuron differentiation; vocalization behavior; zinc ion binding",PF12796;PF16511;PF00536;PF07653;,8.00E-35,CHOYP_SHANK2.1.1,,,,,,,SHAN3_RAT,Rattus norvegicus (Rat),"AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; locomotory exploration behavior [GO:0035641]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; neuromuscular process controlling balance [GO:0050885]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein oligomerization [GO:0051259]; regulation of behavioral fear response [GO:2000822]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of grooming behavior [GO:2000821]; regulation of long term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]" comp159387_c0_seq1,246,45.935,0.3883712,2,0,,9.00E-18,Q75WE7,von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog) (Mast cell surface antigen 1) (Masa-1),von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog) (Mast cell surface antigen 1) (Masa-1),,,PF08487;PF13768;,,,,,,,,,VWA5A_RAT,Rattus norvegicus (Rat), comp159413_c0_seq1,207,42.9952,0.67534044,3,0,,,,,,,,,7.00E-16,CHOYP_LOC100377364.2.2,,,,,,,,, comp159528_c0_seq1,219,44.2922,0.85716073,1,0,,2.00E-08,P10724,Alanine racemase (EC 5.1.1.1),Alanine racemase (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR_GEOSE,Geobacillus stearothermophilus (Bacillus stearothermophilus),D-alanine biosynthetic process [GO:0030632] comp159533_c0_seq1,217,37.788,1.31645308,2,0,,6.00E-12,Q08AM6,Protein VAC14 homolog (Tax1-binding protein 2),Protein VAC14 homolog (Tax1-binding protein 2),GO:0000139; GO:0031901; GO:0005783; GO:0019209; GO:0031902; GO:0019048; GO:0006661; GO:0004872; GO:0007165; GO:0044281,Golgi membrane; early endosome membrane; endoplasmic reticulum; kinase activator activity; late endosome membrane; modulation by virus of host morphology or physiology; phosphatidylinositol biosynthetic process; receptor activity; signal transduction; small molecule metabolic process,PF12755;PF11916;,,,,,,,,,VAC14_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; regulation of lipid kinase activity [GO:0043550]; signal transduction [GO:0007165]; viral process [GO:0016032] comp159543_c0_seq1,225,46.6667,0.74343574,2,0,,4.00E-06,Q8HYJ5,Galactoside 3(4)-L-fucosyltransferase (EC 2.4.1.65) (Alpha-3/4-fucosyltransferase) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III),Galactoside 3(4)-L-fucosyltransferase (EC 2.4.1.65) (Alpha-3/4-fucosyltransferase) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III),GO:0017060; GO:0032580; GO:0036065; GO:0016021; GO:0006486,3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; Golgi cisterna membrane; fucosylation; integral to membrane; protein glycosylation,PF17039;PF00852;,,,,,,,,,FUT3_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp159550_c0_seq1,214,45.7944,1.17193335,2,0,,1.00E-13,Q8HXQ5,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_BOVIN,Bos taurus (Bovine), comp159552_c0_seq1,228,40.7895,0.36349906,3,0,,,,,,,,,2.00E-41,CHOYP_NAN.1.1,,,,,,,,, comp159583_c0_seq1,207,35.7488,0.456151,3,0,,1.00E-08,Q90593,78 kDa glucose-regulated protein (GRP-78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP),78 kDa glucose-regulated protein (GRP-78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP),GO:0005524; GO:0008180; GO:0006983; GO:0006987; GO:0009986; GO:0042149; GO:0071353; GO:0021680; GO:0021589; GO:0034663; GO:0005788; GO:0005793; GO:0030176; GO:0030496; GO:0043066; GO:0030512; GO:0031398; GO:0051603; GO:0043022,ATP binding; COP9 signalosome; ER overload response; activation of signaling protein activity involved in unfolded protein response; cell surface; cellular response to glucose starvation; cellular response to interleukin-4; cerebellar Purkinje cell layer development; cerebellum structural organization; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; integral to endoplasmic reticulum membrane; midbody; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of protein ubiquitination; proteolysis involved in cellular protein catabolic process; ribosome binding,PF00012;,,,,,,,,,GRP78_CHICK,Gallus gallus (Chicken),activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; ER overload response [GO:0006983]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; proteolysis involved in cellular protein catabolic process [GO:0051603]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998] comp159604_c0_seq1,201,41.2935,0.59694149,2,0,,2.00E-09,Q9Z2H2,Regulator of G-protein signaling 6 (RGS6),Regulator of G-protein signaling 6 (RGS6),GO:0007186; GO:0005096; GO:0005737; GO:0005834; GO:0035556; GO:0005886; GO:0004871; GO:0038032,G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; heterotrimeric G-protein complex; intracellular signal transduction; plasma membrane; signal transducer activity; termination of G-protein coupled receptor signaling pathway,PF00610;PF00631;PF00615;,,,,,,,,,RGS6_MOUSE,Mus musculus (Mouse),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547] comp15965_c0_seq1,237,43.8819,0.35682794,3,0,,8.00E-18,Q6P158,Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57),Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57),GO:0005524; GO:0008026; GO:0046872; GO:0003676,ATP binding; ATP-dependent helicase activity; metal ion binding; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;PF05773;PF00642;,,,,,,,,,DHX57_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp16162_c0_seq1,488,44.0574,0.2972915,13,0,,6.00E-46,Q9W5D0,Uncharacterized protein CG42248,Uncharacterized protein CG43867,GO:0005856; GO:0005543,cytoskeleton; phospholipid binding,PF00373;PF00784;PF00169;,1.00E-50,CHOYP_PKHH2.1.1,,,,,,,Y34F_DROME,Drosophila melanogaster (Fruit fly), comp16398_c0_seq1,419,36.5155,0.65831096,5,0,,4.00E-13,Q5M8T2,Solute carrier family 35 member D3 (Fringe connection-like protein 1),Solute carrier family 35 member D3 (Fringe connection-like protein 1),GO:0008643; GO:0016021,carbohydrate transport; integral to membrane,,,,,,,,,,S35D3_HUMAN,Homo sapiens (Human),carbohydrate transport [GO:0008643] comp16715_c0_seq1,357,41.4566,0.3290467,2,2,,6.00E-16,Q6UR05,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp1675_c0_seq1,204,46.0784,0.38534761,6,0,,2.00E-33,P41042,40S ribosomal protein S4,40S ribosomal protein S4,GO:0051298; GO:0000022; GO:0019843; GO:0005840; GO:0003735; GO:0006412,centrosome duplication; mitotic spindle elongation; rRNA binding; ribosome; structural constituent of ribosome; translation,PF16121;PF00467;PF00900;PF08071;PF01479;,1.00E-64,CHOYP_PDHA1.1.1,1.00E-30,ruditapes2_c3108,,,,,RS4_DROME,Drosophila melanogaster (Fruit fly),centrosome duplication [GO:0051298]; centrosome organization [GO:0051297]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; translation [GO:0006412] comp16791_c0_seq1,312,44.5513,0.67341484,9,0,,2.00E-35,Q98SP7,Bardet-Biedl syndrome 2 protein homolog,Bardet-Biedl syndrome 2 protein homolog,GO:0070121; GO:0042384; GO:0060170; GO:0005737; GO:0007368; GO:0046907; GO:0032402; GO:0005815; GO:0051877,Kupffer's vesicle development; cilium assembly; cilium membrane; cytoplasm; determination of left/right symmetry; intracellular transport; melanosome transport; microtubule organizing center; pigment granule aggregation in cell center,PF14782;PF14783;PF14781;,3.00E-42,CHOYP_LOC100375650.1.1,,,,,,,BBS2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; nonmotile primary cilium assembly [GO:0035058]; pigment granule aggregation in cell center [GO:0051877]; protein localization to ciliary membrane [GO:1903441] comp16799_c0_seq1,294,42.8571,0.22762609,8,0,,1.00E-10,Q38SD2,Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1),Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1),GO:0005524; GO:0005525; GO:0046872; GO:0005739; GO:0004674; GO:0007264,ATP binding; GTP binding; metal ion binding; mitochondrion; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF12796;PF16095;PF00069;PF08477;,,,,,,,,,LRRK1_HUMAN,Homo sapiens (Human),bone resorption [GO:0045453]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; small GTPase mediated signal transduction [GO:0007264] comp1683_c0_seq1,215,40,0.23415141,0,3,,7.00E-07,Q8K078,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0006811; GO:0005886; GO:0005215,integral to membrane; ion transport; plasma membrane; transporter activity,PF07648;PF03137;,,,,,,,,,SO4A1_MOUSE,Mus musculus (Mouse),organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp16857_c0_seq1,216,39.8148,1.70663065,3,0,,2.00E-21,Q6GNL1,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)",GO:0016266; GO:0001525; GO:0016263; GO:0016021; GO:0001822; GO:0046872,O-glycan processing; angiogenesis; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; kidney development; metal ion binding,PF02434;,,,,,,,,,C1GLT_XENLA,Xenopus laevis (African clawed frog),angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing [GO:0016266] comp16918_c0_seq1,207,45.4106,0.65913716,3,0,,4.00E-27,Q9D665,Short-chain dehydrogenase/reductase family 42E member 1 (EC 1.1.1.-),Short-chain dehydrogenase/reductase family 42E member 1 (EC 1.1.1.-),GO:0003854; GO:0016021; GO:0006694,3-beta-hydroxy-delta5-steroid dehydrogenase activity; integral to membrane; steroid biosynthetic process,PF01073;,3.00E-21,CHOYP_D42E1.2.2,,,,,,,D42E1_MOUSE,Mus musculus (Mouse),steroid biosynthetic process [GO:0006694] comp16998_c0_seq1,292,37.3288,0.60330152,8,0,,3.00E-07,P07053,Pathogenesis-related protein 1B (PR-1B),Pathogenesis-related protein 1B (PR-1B),GO:0006952; GO:0005576; GO:0009607; GO:0005773,defense response; extracellular region; response to biotic stimulus; vacuole,PF00188;,,,,,,,,,PR1B_TOBAC,Nicotiana tabacum (Common tobacco),defense response [GO:0006952]; response to biotic stimulus [GO:0009607] comp17045_c0_seq1,338,44.3787,1.03354563,7,0,,6.00E-13,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp17113_c0_seq1,239,40.5858,0.72728546,6,0,,1.00E-10,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp17141_c0_seq1,239,38.4937,0.91430172,3,4,,3.00E-08,Q05654,,,,,,,,,,,,,,RTF21_SCHPO,, comp17180_c0_seq1,306,49.6732,0.32248244,10,0,,1.00E-21,Q9NR16,Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b),Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b),GO:0005576; GO:0016021; GO:0005886; GO:0005044,extracellular region; integral to membrane; plasma membrane; scavenger receptor activity,PF00530;,2.00E-13,CHOYP_DMBT1.9.34,,,,,,,C163B_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp17200_c0_seq1,246,31.7073,1.78635431,0,3,,,,,,,,,,,4.00E-11,ruditapes_c6976,,,,,,, comp17206_c0_seq1,364,45.3297,0.80800492,7,4,,3.00E-10,Q5VYY1,Ankyrin repeat domain-containing protein 22,Ankyrin repeat domain-containing protein 22,,,PF12796;,,,,,,,,,ANR22_HUMAN,Homo sapiens (Human), comp1726_c0_seq1,217,46.0829,0.43618373,4,0,,2.00E-07,P56597,Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5),Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0003351; GO:0043066; GO:0004550; GO:0009116; GO:0036126; GO:0007286; GO:0021591,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; epithelial cilium movement; negative regulation of apoptotic process; nucleoside diphosphate kinase activity; nucleoside metabolic process; sperm flagellum; spermatid development; ventricular system development,PF05186;PF00334;,,,6.00E-15,ruditapes_c10493,,,,,NDK5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591] comp1744_c0_seq1,323,49.8452,0.35108696,5,3,,4.00E-37,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,4.00E-66,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp17683_c0_seq1,212,47.6415,0.67140974,3,0,,4.00E-30,P61866,60S ribosomal protein L12,60S ribosomal protein L12,GO:0003723; GO:0005840; GO:0003735; GO:0006412,RNA binding; ribosome; structural constituent of ribosome; translation,PF00298;PF03946;,3.00E-59,CHOYP_LOC100908688.4.5,6.00E-21,ruditapes2_lrc6060,,,,,RL12_CAEEL,Caenorhabditis elegans,ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp1776_c0_seq1,232,43.1034,1.12971796,0,0,,,,,,,,,1.00E-19,CHOYP_LOC658611.1.1,,,,,,,,, comp17790_c0_seq1,266,47.7444,0.8058464,8,0,,3.00E-08,Q9D5U8,Cyclic nucleotide-binding domain-containing protein 2,Cyclic nucleotide-binding domain-containing protein 2,,,PF00027;,2.00E-12,CHOYP_LOC100376104.1.2,,,,,,,CT152_MOUSE,Mus musculus (Mouse),spermatogenesis [GO:0007283] comp17809_c0_seq1,369,46.8835,0.91584831,6,4,,7.00E-28,O60507,Protein-tyrosine sulfotransferase 1 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 1) (TPST-1),Protein-tyrosine sulfotransferase 1 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 1) (TPST-1),GO:0000139; GO:0006954; GO:0016021; GO:0016020; GO:0006478; GO:0008476,Golgi membrane; inflammatory response; integral to membrane; membrane; peptidyl-tyrosine sulfation; protein-tyrosine sulfotransferase activity,,1.00E-15,CHOYP_BRAFLDRAFT_89531.1.1,,,,,,,TPST1_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; peptidyl-tyrosine sulfation [GO:0006478] comp17902_c0_seq1,218,61.9266,1.16440199,4,0,,3.00E-07,Q5WKY7,Inosose dehydratase (EC 4.2.1.44) (2-keto-myo-inositol dehydratase) (2KMI dehydratase),Inosose dehydratase (EC 4.2.1.44) (2-keto-myo-inositol dehydratase) (2KMI dehydratase),GO:0019310; GO:0030145; GO:0050114,inositol catabolic process; manganese ion binding; myo-inosose-2 dehydratase activity,PF01261;,,,,,,,,,IOLE_BACSK,Bacillus clausii (strain KSM-K16),inositol catabolic process [GO:0019310] comp17978_c0_seq1,636,40.7233,0.11433557,11,0,,6.00E-07,Q9NY15,"Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)","Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)",GO:0007155; GO:0007267; GO:0042742; GO:0030666; GO:0005540; GO:0006954; GO:0005887; GO:0030169; GO:0005041; GO:0016525; GO:0015035; GO:0005044,cell adhesion; cell-cell signaling; defense response to bacterium; endocytic vesicle membrane; hyaluronic acid binding; inflammatory response; integral to plasma membrane; low-density lipoprotein particle binding; low-density lipoprotein receptor activity; negative regulation of angiogenesis; protein disulfide oxidoreductase activity; scavenger receptor activity,PF12947;PF02469;PF00193;,,,,,,,,,STAB1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; receptor-mediated endocytosis [GO:0006898] comp18200_c0_seq1,221,41.629,0.75182962,2,0,,2.00E-08,Q008S8,Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH),Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH),GO:0005089; GO:0035023,Rho guanyl-nucleotide exchange factor activity; regulation of Rho protein signal transduction,PF14252;PF12937;PF00621;,4.00E-26,CHOYP_LOC100369302.3.3,,,,,,,ECT2L_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp18227_c0_seq1,332,44.2771,0.37913057,5,0,,8.00E-47,Q9VI93,Zinc finger protein rotund (Zinc finger protein roughened eye),Zinc finger protein rotund (Zinc finger protein roughened eye),GO:0003705; GO:0048749; GO:0007480; GO:0046872; GO:0000122; GO:0003676; GO:0005634,RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; compound eye development; imaginal disc-derived leg morphogenesis; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleic acid binding; nucleus,PF00096;,6.00E-39,CHOYP_LOC659822.1.1,,,,,,,RN_DROME,Drosophila melanogaster (Fruit fly),"cell fate specification [GO:0001708]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg morphogenesis [GO:0007480]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]" comp18251_c0_seq1,330,46.9697,0.44177917,13,0,,1.00E-17,Q3UGM2,Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10),Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10),GO:0005524; GO:0046872; GO:0018108; GO:0004674; GO:0004713,ATP binding; metal ion binding; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;,,,,,,,,,NEK10_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; protein phosphorylation [GO:0006468] comp18267_c0_seq1,236,44.4915,0.60859493,3,1,,1.00E-08,Q58DA5,Neurotrimin,Neurotrimin,GO:0031225; GO:0007155; GO:0005886,anchored to membrane; cell adhesion; plasma membrane,PF07679;,,,,,,,,,NTRI_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155] comp18293_c0_seq1,203,35.9606,0.45947061,1,1,,5.00E-30,Q63486,Ras-related GTP-binding protein A (Rag A) (RagA),Ras-related GTP-binding protein A (Rag A) (RagA),GO:0005525; GO:0005794; GO:0006915; GO:0008219; GO:0034613; GO:0071230; GO:0005764; GO:0019048; GO:0005634; GO:0051219; GO:0045919; GO:0046982; GO:0042803,GTP binding; Golgi apparatus; apoptotic process; cell death; cellular protein localization; cellular response to amino acid stimulus; lysosome; modulation by virus of host morphology or physiology; nucleus; phosphoprotein binding; positive regulation of cytolysis; protein heterodimerization activity; protein homodimerization activity,PF04670;,2.00E-30,CHOYP_RRAGA.1.1,,,,,,,RRAGA_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; cell death [GO:0008219]; cellular protein localization [GO:0034613]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of autophagy [GO:0010507]; positive regulation of cytolysis [GO:0045919]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506] comp18317_c0_seq1,268,43.2836,0.80347594,11,0,,1.00E-09,Q8IZJ3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,GO:0005615; GO:0010951; GO:0005886; GO:0004867,extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;,3.00E-15,CHOYP_TRIADDRAFT_55768.1.2,,,,,,,CPMD8_HUMAN,Homo sapiens (Human), comp18421_c0_seq1,253,46.6403,0.7876092,6,0,,,,,,,,,1.00E-40,CHOYP_PDE3A.3.3,,,,,,,,, comp18490_c0_seq1,209,40.1914,0.84098035,7,0,,2.00E-06,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp18526_c0_seq1,242,33.0579,0.31074699,1,1,,,,,,,,,4.00E-14,CHOYP_contig_028860,,,,,,,,, comp1868_c0_seq1,310,45.1613,0.57415982,4,4,,5.00E-14,Q8N7A1,Kelch domain-containing protein 1,Kelch domain-containing protein 1,GO:0005737,cytoplasm,,,,,,,,,,KLDC1_HUMAN,Homo sapiens (Human), comp19032_c0_seq1,281,58.0071,0.89161021,3,6,,1.00E-41,P0A522,ATP-dependent Clp protease ATP-binding subunit ClpC1,,GO:0005524; GO:0016887; GO:0005618; GO:0005829; GO:0040007; GO:0005886; GO:0044183,ATP binding; ATPase activity; cell wall; cytosol; growth; plasma membrane; protein binding involved in protein folding,,,,,,,,,,CLPC_MYCTU,, comp1910_c1_seq1,262,41.9847,0.52600766,6,0,,3.00E-21,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp19265_c0_seq1,243,62.5514,0.84488965,0,5,,7.00E-38,Q6A947,Glutamine amidotransferase subunit PdxT (EC 2.6.-.-) (Glutamine amidotransferase glutaminase subunit PdxT),Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2),GO:0006543; GO:0042823; GO:0016740,glutamine catabolic process; pyridoxal phosphate biosynthetic process; transferase activity,PF01174;,,,,,,,,,PDXT_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819] comp19338_c0_seq1,210,38.5714,0.52099947,4,11,,,,,,,,,5.00E-18,CHOYP_BRAFLDRAFT_106560.14.14,,,,,,,,, comp19436_c0_seq1,211,44.5498,0.82132595,3,0,,5.00E-15,Q6ZN30,Zinc finger protein basonuclin-2,Zinc finger protein basonuclin-2,GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,BNC2_HUMAN,Homo sapiens (Human),"endochondral bone growth [GO:0003416]; mesenchyme development [GO:0060485]; palate development [GO:0060021]; regulation of transcription, DNA-templated [GO:0006355]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]" comp19457_c0_seq1,208,38.4615,0.91956871,0,4,,1.00E-09,Q69ZF8,E3 ubiquitin-protein ligase MSL2 (EC 6.3.2.-) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184),E3 ubiquitin-protein ligase MSL2 (EC 6.3.2.-) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184),GO:0072487; GO:0043984; GO:0016874; GO:0008270,MSL complex; histone H4-K16 acetylation; ligase activity; zinc ion binding,PF16682;PF16685;,,,,,,,,,MSL2_MOUSE,Mus musculus (Mouse),histone H4-K16 acetylation [GO:0043984] comp19461_c0_seq1,307,51.7915,0.46667162,9,0,,,,,,,,,1.00E-14,CHOYP_RGD1561408.2.2,,,,,,,,, comp19591_c0_seq1,234,47.0085,0.16456883,3,3,,3.00E-26,Q59H18,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004672; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein kinase activity; protein serine/threonine kinase activity,PF12796;PF07714;,6.00E-18,CHOYP_LOC576866.1.1,,,,,,,TNI3K_HUMAN,Homo sapiens (Human),bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027] comp195_c0_seq1,232,51.7241,0.97764054,1,2,,1.00E-14,Q8HXQ0,Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),Superoxide dismutase [Cu-Zn] (EC 1.15.1.1),GO:0000187; GO:0008089; GO:0006309; GO:0060088; GO:0007569; GO:0006879; GO:0051087; GO:0005507; GO:0031410; GO:0005829; GO:0032839; GO:0006302; GO:0007566; GO:0031012; GO:0005615; GO:0006749; GO:0060047; GO:0050665; GO:0007626; GO:0005739; GO:0046716; GO:0002262; GO:0045541; GO:0043524; GO:0060052; GO:0043025; GO:0005634; GO:0001541; GO:0032287; GO:0005886; GO:0001819; GO:1902177; GO:0032930; GO:0043234; GO:0030346; GO:0032314; GO:0008217; GO:0051881; GO:0040014; GO:0060087; GO:0019430; GO:0048678; GO:0042493; GO:0045471; GO:0009408; GO:0042542; GO:0001895; GO:0008090; GO:0007605; GO:0007283; GO:0042554; GO:0004784; GO:0008270,activation of MAPK activity; anterograde axon cargo transport; apoptotic DNA fragmentation; auditory receptor cell stereocilium organization; cell aging; cellular iron ion homeostasis; chaperone binding; copper ion binding; cytoplasmic vesicle; cytosol; dendrite cytoplasm; double-strand break repair; embryo implantation; extracellular matrix; extracellular space; glutathione metabolic process; heart contraction; hydrogen peroxide biosynthetic process; locomotory behavior; mitochondrion; muscle cell cellular homeostasis; myeloid cell homeostasis; negative regulation of cholesterol biosynthetic process; negative regulation of neuron apoptotic process; neurofilament cytoskeleton organization; neuronal cell body; nucleus; ovarian follicle development; peripheral nervous system myelin maintenance; plasma membrane; positive regulation of cytokine production; positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; positive regulation of superoxide anion generation; protein complex; protein phosphatase 2B binding; regulation of Rac GTPase activity; regulation of blood pressure; regulation of mitochondrial membrane potential; regulation of multicellular organism growth; relaxation of vascular smooth muscle; removal of superoxide radicals; response to axon injury; response to drug; response to ethanol; response to heat; response to hydrogen peroxide; retina homeostasis; retrograde axon cargo transport; sensory perception of sound; spermatogenesis; superoxide anion generation; superoxide dismutase activity; zinc ion binding,PF00080;,,,,,,,,,SODC_MACMU,Macaca mulatta (Rhesus macaque),activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; apoptotic DNA fragmentation [GO:0006309]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; double-strand break repair [GO:0006302]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226] comp19649_c0_seq2,422,41.7062,0.72854145,8,0,,,,,,,,,6.00E-15,CHOYP_SMP_147320.1.1,,,,,,,,, comp19821_c0_seq1,251,41.0359,0.4772803,2,0,,6.00E-06,O14867,Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303),Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303),GO:0001078; GO:0020037; GO:0005634; GO:0061418; GO:0000083; GO:0000117; GO:0043565,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; heme binding; nucleus; regulation of transcription from RNA polymerase II promoter in response to hypoxia; regulation of transcription involved in G1/S transition of mitotic cell cycle; regulation of transcription involved in G2/M transition of mitotic cell cycle; sequence-specific DNA binding,PF00651;PF03131;,,,,,,,,,BACH1_HUMAN,Homo sapiens (Human),"DNA repair [GO:0006281]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0000117]" comp19983_c0_seq1,220,35.9091,0.85660685,4,4,,4.00E-07,Q9N0E3,Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor),Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF13855;,,,,,,,,,RTN4R_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),negative regulation of axon extension [GO:0030517]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547] comp20017_c0_seq1,284,45.7746,0.4739902,9,0,,4.00E-08,P0C091,FRAS1-related extracellular matrix protein 3,FRAS1-related extracellular matrix protein 3,GO:0005604; GO:0007155; GO:0007154; GO:0016021; GO:0046872,basement membrane; cell adhesion; cell communication; integral to membrane; metal ion binding,PF03160;,,,,,,,,,FREM3_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154] comp20101_c0_seq1,201,41.791,0.80160714,3,5,,5.00E-08,Q99NF1,"Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)","Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)",GO:0016121; GO:0016116; GO:0046872; GO:0005739; GO:0016702; GO:0051881; GO:2000377; GO:0042574; GO:0042573,"carotene catabolic process; carotenoid metabolic process; metal ion binding; mitochondrion; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; regulation of mitochondrial membrane potential; regulation of reactive oxygen species metabolic process; retinal metabolic process; retinoic acid metabolic process",PF03055;,,,,,,,,,BCDO2_MOUSE,Mus musculus (Mouse),carotene catabolic process [GO:0016121]; carotene metabolic process [GO:0016119]; carotenoid metabolic process [GO:0016116]; oxidation-reduction process [GO:0055114]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; xanthophyll metabolic process [GO:0016122] comp2011_c0_seq1,256,38.2812,0.69087076,3,1,,,,,,,,,,,1.00E-18,ruditapes_c30970,,,,,,, comp2012_c0_seq1,253,34.3874,0,2,0,,2.00E-19,Q5XIG6,N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2),N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2),GO:0005524; GO:0033858; GO:0005737; GO:0004335; GO:0006012,ATP binding; N-acetylgalactosamine kinase activity; cytoplasm; galactokinase activity; galactose metabolic process,PF10509;PF08544;PF00288;,6.00E-12,CHOYP_GALK2.1.2,,,,,,,GALK2_RAT,Rattus norvegicus (Rat),galactose metabolic process [GO:0006012] comp20142_c0_seq1,682,34.1642,0.15532174,35,17,,1.00E-10,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp20168_c0_seq1,253,38.7352,0.31750496,10,9,,1.00E-38,Q9NSY1,BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1),BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1),GO:0005524; GO:0005634; GO:0019208; GO:0004674; GO:0030500,ATP binding; nucleus; phosphatase regulator activity; protein serine/threonine kinase activity; regulation of bone mineralization,PF15282;PF00069;,3.00E-34,CHOYP_AAK1.1.1,,,,,,,BMP2K_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468]; regulation of bone mineralization [GO:0030500] comp20185_c0_seq1,354,45.4802,0.75187957,7,22,,2.00E-13,Q8IVS8,Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4),Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4),GO:0005524; GO:0005794; GO:0008887; GO:0005739; GO:0006468,ATP binding; Golgi apparatus; glycerate kinase activity; mitochondrion; protein phosphorylation,PF13660;PF05161;,,,,,,,,,GLCTK_HUMAN,Homo sapiens (Human),fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; protein phosphorylation [GO:0006468] comp20190_c0_seq1,354,46.6102,0.62702885,5,22,,1.00E-07,Q5DRB8,Protocadherin gamma-A2 (PCDH-gamma-A2),Protocadherin gamma-A2 (PCDH-gamma-A2),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG2_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp20199_c0_seq1,201,35.3234,0,5,8,,,,,,,,,,,2.00E-21,ruditapes_c13430,,,,,,, comp20230_c0_seq1,485,44.7423,0.84522098,14,16,,3.00E-56,Q3MII6,TBC1 domain family member 25,TBC1 domain family member 25,GO:0005097; GO:0005776; GO:0006914; GO:0031410; GO:1901096,Rab GTPase activator activity; autophagic vacuole; autophagy; cytoplasmic vesicle; regulation of autophagic vacuole maturation,PF00566;,1.00E-67,CHOYP_LOC100678410.1.1,,,,,,,TBC25_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; regulation of autophagosome maturation [GO:1901096]; regulation of vesicle fusion [GO:0031338] comp20233_c0_seq1,348,56.8966,0.90349716,2,26,,2.00E-23,P64314,Probable ATP-dependent helicase DinG homolog (EC 3.6.4.12),,GO:0005524; GO:0008026; GO:0003677; GO:0006310; GO:0006281; GO:0005886,ATP binding; ATP-dependent helicase activity; DNA binding; DNA recombination; DNA repair; plasma membrane,,,,,,,,,,DING_MYCTU,, comp20243_c0_seq1,302,42.7152,0.87297971,7,13,,2.00E-27,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp20248_c0_seq1,230,47.3913,1.09629191,1,17,,4.00E-07,P34257,Transposable element Tc3 transposase,Transposable element Tc3 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF11427;PF01498;,,,,,,,,,TC3A_CAEEL,Caenorhabditis elegans,"developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp20255_c0_seq1,466,28.5408,0.5316509,11,21,,3.00E-18,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp20268_c0_seq1,789,40.1774,0.31612696,24,36,,1.00E-14,O96006,Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog),Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog),GO:0003677; GO:0046872; GO:0000228; GO:0004803,DNA binding; metal ion binding; nuclear chromosome; transposase activity,PF05699;PF02892;,,,,,,,,,ZBED1_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp20275_c0_seq1,303,44.8845,0.46031217,2,13,,6.00E-36,E7EY42,Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II),Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II),GO:0005789; GO:0016021; GO:0006659; GO:0016740,endoplasmic reticulum membrane; integral to membrane; phosphatidylserine biosynthetic process; transferase activity,PF03034;,3.00E-22,CHOYP_PTSS2.1.1,,,,,,,PTSS2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654] comp20276_c0_seq1,325,41.5385,0.57268878,5,24,,1.00E-19,Q86X52,Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1),Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1),GO:0032580; GO:0000139; GO:0050510; GO:0005975; GO:0030206; GO:0005576; GO:0047238; GO:0016021; GO:0046872; GO:0030279; GO:0031667,Golgi cisterna membrane; Golgi membrane; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; extracellular region; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; integral to membrane; metal ion binding; negative regulation of ossification; response to nutrient levels,PF05679;,,,,,,,,,CHSS1_HUMAN,Homo sapiens (Human),bone morphogenesis [GO:0060349]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] comp20291_c0_seq1,208,43.2692,0.65862867,3,23,,4.00E-20,Q8CBW7,Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein),Cysteine-rich hydrophobic domain-containing protein 1 (Brain X-linked protein),GO:0016023; GO:0005886,cytoplasmic membrane-bounded vesicle; plasma membrane,PF10256;,1.00E-31,CHOYP_LOC100366987.2.2,,,,,,,CHIC1_MOUSE,Mus musculus (Mouse),transport [GO:0006810] comp20313_c0_seq1,419,49.8807,0.80769691,9,37,,1.00E-43,P29074,Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),GO:0005737; GO:0005856; GO:0009898; GO:0004726,cytoplasm; cytoskeleton; internal side of plasma membrane; non-membrane spanning protein tyrosine phosphatase activity,PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;,8.00E-70,CHOYP_PTN4.2.2,2.00E-32,ruditapes_c20385,,,,,PTN4_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470] comp20324_c0_seq1,322,48.4472,0.4250041,10,23,,1.00E-29,P19137,Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),GO:0060445; GO:0007155; GO:0007166; GO:0005911; GO:0060441; GO:0045198; GO:0005201; GO:0043208; GO:0005606; GO:0002011; GO:0031175; GO:0030155; GO:0030334; GO:0045995; GO:0061304,branching involved in salivary gland morphogenesis; cell adhesion; cell surface receptor signaling pathway; cell-cell junction; epithelial tube branching involved in lung morphogenesis; establishment of epithelial cell apical/basal polarity; extracellular matrix structural constituent; glycosphingolipid binding; laminin-1 complex; morphogenesis of an epithelial sheet; neuron projection development; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; retinal blood vessel morphogenesis,PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;,,,,,,,,,LAMA1_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888] comp20325_c0_seq1,297,38.0471,0.58014934,0,24,,2.00E-24,Q9V3L1,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)],Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)],GO:0000137; GO:0000139; GO:0016055; GO:0015016; GO:0005783; GO:0007427; GO:0008543; GO:0006024; GO:0007507; GO:0015014; GO:0030210; GO:0016787; GO:0008587; GO:0007474; GO:0016021; GO:0048312; GO:0007509; GO:0007428; GO:0060828; GO:0090097; GO:0045570; GO:0007367; GO:0048488,"Golgi cis cisterna; Golgi membrane; Wnt receptor signaling pathway; [heparan sulfate]-glucosamine N-sulfotransferase activity; endoplasmic reticulum; epithelial cell migration, open tracheal system; fibroblast growth factor receptor signaling pathway; glycosaminoglycan biosynthetic process; heart development; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin biosynthetic process; hydrolase activity; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; intracellular distribution of mitochondria; mesoderm migration involved in gastrulation; primary branching, open tracheal system; regulation of canonical Wnt receptor signaling pathway; regulation of decapentaplegic signaling pathway; regulation of imaginal disc growth; segment polarity determination; synaptic vesicle endocytosis",PF12062;PF00685;,,,,,,,,,NDST_DROME,Drosophila melanogaster (Fruit fly),"cell surface receptor signaling pathway [GO:0007166]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; intracellular distribution of mitochondria [GO:0048312]; mesoderm migration involved in gastrulation [GO:0007509]; primary branching, open tracheal system [GO:0007428]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of decapentaplegic signaling pathway [GO:0090097]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; synaptic vesicle endocytosis [GO:0048488]; Wnt signaling pathway [GO:0016055]" comp20353_c0_seq1,640,42.1875,0.3984526,11,25,,2.00E-10,Q76B49,CD63 antigen (CD antigen CD63),CD63 antigen (CD antigen CD63),GO:0009986; GO:0034613; GO:0016021; GO:0031902; GO:0005765; GO:0005886; GO:2000680,cell surface; cellular protein localization; integral to membrane; late endosome membrane; lysosomal membrane; plasma membrane; regulation of rubidium ion transport,PF00335;,,,,,,,,,CD63_FELCA,Felis catus (Cat) (Felis silvestris catus),cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] comp20372_c0_seq1,416,41.1058,0.62922174,18,13,,,,,,,,,7.00E-14,CHOYP_LOC100372028.1.1,6.00E-44,ruditapes_c13928,,,,,,, comp20378_c0_seq2,810,44.4444,0.47564587,10,1,,5.00E-32,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp20401_c0_seq1,207,40.5797,0.94547661,0,18,,8.00E-16,Q54513,Transposase for insertion sequence IS1202,Transposase for insertion sequence IS1202,GO:0003677; GO:0015074; GO:0006310; GO:0032196,DNA binding; DNA integration; DNA recombination; transposition,PF00665;,,,,,,,,,TRA2_STREE,Streptococcus pneumoniae,DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196] comp20414_c0_seq1,586,43.8567,0.4652495,25,11,,4.00E-23,Q3UGM2,Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10),Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10),GO:0005524; GO:0046872; GO:0018108; GO:0004674; GO:0004713,ATP binding; metal ion binding; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;,,,,,,,,,NEK10_MOUSE,Mus musculus (Mouse),chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; protein phosphorylation [GO:0006468] comp20427_c0_seq1,341,47.8006,0.36350146,5,2,,2.00E-07,O60610,Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1),Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1),GO:0030041; GO:0071420; GO:0005737; GO:0007010; GO:0072686; GO:0043005; GO:0031175; GO:0035372; GO:0005102; GO:0008360; GO:0032886; GO:0051279; GO:0032587; GO:0007605,actin filament polymerization; cellular response to histamine; cytoplasm; cytoskeleton organization; mitotic spindle; neuron projection; neuron projection development; protein localization to microtubule; receptor binding; regulation of cell shape; regulation of microtubule-based process; regulation of release of sequestered calcium ion into cytosol; ruffle membrane; sensory perception of sound,PF06345;PF06346;PF06367;PF06371;PF02181;,4.00E-15,CHOYP_DIAP2.1.1,,,,,,,DIAP1_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; cellular response to histamine [GO:0071420]; cytoskeleton organization [GO:0007010]; positive regulation of cell migration [GO:0030335]; protein localization to microtubule [GO:0035372]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of microtubule-based process [GO:0032886]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; sensory perception of sound [GO:0007605] comp20427_c0_seq2,295,39.661,0.44179612,2,11,,2.00E-12,O70566,Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3),Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3),GO:0003779; GO:0030041; GO:0030154; GO:0007275; GO:0048477,actin binding; actin filament polymerization; cell differentiation; multicellular organismal development; oogenesis,PF06345;PF06367;PF06371;PF02181;,,,,,,,,,DIAP2_MOUSE,Mus musculus (Mouse),actin filament polymerization [GO:0030041]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477] comp20453_c0_seq1,208,41.3462,0.57640604,3,26,,3.00E-25,Q9DBH5,Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36),Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36),GO:0000139; GO:0005793; GO:0016021; GO:0046872; GO:0015031,Golgi membrane; endoplasmic reticulum-Golgi intermediate compartment; integral to membrane; metal ion binding; protein transport,PF03388;,,,,,,,,,LMAN2_MOUSE,Mus musculus (Mouse),"positive regulation of phagocytosis [GO:0050766]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp20457_c0_seq1,218,60.5505,1.01133506,0,24,,1.00E-37,Q9XF97,60S ribosomal protein L4 (L1),60S ribosomal protein L4 (L1),GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF14374;PF00573;,9.00E-28,CHOYP_ADA17.1.3,3.00E-31,ruditapes_c1609,,,,,RL4_PRUAR,Prunus armeniaca (Apricot) (Armeniaca vulgaris),translation [GO:0006412] comp20459_c0_seq1,387,45.7364,0.2977002,12,12,,3.00E-09,P49695,Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1),Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;PF00400;,3.00E-31,CHOYP_LOC100892044.2.2,,,,,,,PKWA_THECU,Thermomonospora curvata, comp20467_c0_seq1,218,44.9541,0.82126728,0,14,,5.00E-27,P57722,Poly(rC)-binding protein 3 (Alpha-CP3),Poly(rC)-binding protein 3 (Alpha-CP3),GO:0003677; GO:0003723; GO:0005829; GO:0005739; GO:0005634; GO:0030529,DNA binding; RNA binding; cytosol; mitochondrion; nucleus; ribonucleoprotein complex,PF00013;,,,,,,,,,PCBP3_MOUSE,Mus musculus (Mouse),negative regulation of transcription from RNA polymerase II promoter [GO:0000122] comp20467_c0_seq2,203,45.3202,0.86769591,5,0,,3.00E-23,O19048,Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1),Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1),GO:0003723; GO:0005634; GO:0030529; GO:0003697,RNA binding; nucleus; ribonucleoprotein complex; single-stranded DNA binding,PF00013;,5.00E-37,CHOYP_LOC100905944.1.1,,,,,,,PCBP1_RABIT,Oryctolagus cuniculus (Rabbit), comp20496_c0_seq1,452,41.8142,0.76348688,6,39,,7.00E-53,A7E300,Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12),Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12),GO:0005096; GO:0005737; GO:0005925; GO:0008289; GO:0016020; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; focal adhesion; lipid binding; membrane; positive regulation of GTPase activity; signal transduction,PF00620;PF07647;PF01852;,4.00E-36,CHOYP_RHG07.1.1,,,,,,,RHG07_BOVIN,Bos taurus (Bovine),regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] comp20514_c0_seq1,268,43.6567,1.02793906,1,27,,5.00E-11,Q92832,Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1),Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1),GO:0005509; GO:0030154; GO:0005576; GO:2000599; GO:0033689; GO:0007399; GO:0005635; GO:0048471; GO:0030501; GO:0045669; GO:0010468,calcium ion binding; cell differentiation; extracellular region; negative regulation of cyclin catabolic process; negative regulation of osteoblast proliferation; nervous system development; nuclear envelope; perinuclear region of cytoplasm; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; regulation of gene expression,PF12947;PF07645;PF12661;PF00093;,,,,,,,,,NELL1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; negative regulation of cyclin catabolic process [GO:2000599]; negative regulation of osteoblast proliferation [GO:0033689]; nervous system development [GO:0007399]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of gene expression [GO:0010468] comp20518_c0_seq1,233,40.3433,0.43985773,2,24,,7.00E-17,O35678,Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL),Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL),GO:0046464; GO:0047372; GO:0019369; GO:0004091; GO:0006633; GO:0060292; GO:2000124; GO:0050727; GO:0051930; GO:0019433,acylglycerol catabolic process; acylglycerol lipase activity; arachidonic acid metabolic process; carboxylesterase activity; fatty acid biosynthetic process; long term synaptic depression; regulation of endocannabinoid signaling pathway; regulation of inflammatory response; regulation of sensory perception of pain; triglyceride catabolic process,PF12146;,,,,,,,,,MGLL_MOUSE,Mus musculus (Mouse),acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; long term synaptic depression [GO:0060292]; regulation of axon extension [GO:0030516]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433] comp20529_c0_seq1,247,44.9393,1.07182608,0,21,,6.00E-14,Q8K4F2,Arachidonate 15-lipoxygenase B (15-LOX-B) (EC 1.13.11.33) (15-lipoxygenase 2) (15-LOX-2) (Arachidonate 15-lipoxygenase type II) (Linoleate 13-lipoxygenase 15-LOb) (EC 1.13.11.-),Arachidonate 15-lipoxygenase B (15-LOX-B) (EC 1.13.11.33) (15-lipoxygenase 2) (15-LOX-2) (Arachidonate 15-lipoxygenase type II) (Linoleate 13-lipoxygenase 15-LOb) (EC 1.13.11.-),GO:0050473; GO:0019369; GO:0005856; GO:0005829; GO:0051122; GO:0005506; GO:0019372; GO:0005634; GO:0005886,arachidonate 15-lipoxygenase activity; arachidonic acid metabolic process; cytoskeleton; cytosol; hepoxilin biosynthetic process; iron ion binding; lipoxygenase pathway; nucleus; plasma membrane,PF00305;PF01477;,7.00E-17,CHOYP_LOC584481.5.10,,,,,,,LX15B_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369]; hepoxilin biosynthetic process [GO:0051122]; lipoxygenase pathway [GO:0019372] comp20539_c0_seq1,341,42.8152,0.45783526,22,12,,7.00E-21,P20715,3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34),3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34),GO:0050661; GO:0006695; GO:0015936; GO:0005789; GO:0004420; GO:0016021; GO:0008299,NADP binding; cholesterol biosynthetic process; coenzyme A metabolic process; endoplasmic reticulum membrane; hydroxymethylglutaryl-CoA reductase (NADPH) activity; integral to membrane; isoprenoid biosynthetic process,PF00368;PF12349;,,,,,,,,,HMDH_XENLA,Xenopus laevis (African clawed frog),cholesterol biosynthetic process [GO:0006695]; coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299] comp20548_c0_seq1,311,39.2283,0.58947978,4,28,,2.00E-15,Q5R8D9,Heat shock 70 kDa protein 13 (Stress-70 protein chaperone microsome-associated 60 kDa protein),Heat shock 70 kDa protein 13 (Stress-70 protein chaperone microsome-associated 60 kDa protein),GO:0005524; GO:0005783,ATP binding; endoplasmic reticulum,PF00012;,7.00E-12,CHOYP_NEMVEDRAFT_V1G243437.1.1,,,,,,,HSP13_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp2058_c0_seq1,268,40.6716,0.28435914,6,6,,,,,,,,,,,1.00E-24,ruditapes_c27756,,,,,,, comp20610_c0_seq1,293,30.7167,1.23530851,5,23,,4.00E-07,P33749,Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4),Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4),GO:0000982; GO:0001324; GO:0006338; GO:0000987; GO:0005829; GO:0046872; GO:0005634; GO:0061401; GO:0061402; GO:0061422; GO:0061412; GO:0061395; GO:0061410; GO:0061409; GO:0061406; GO:0061408; GO:0061407; GO:0061405; GO:0061404; GO:0061403; GO:0097236; GO:0061434; GO:0001302,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; age-dependent response to oxidative stress involved in chronological cell aging; chromatin remodeling; core promoter proximal region sequence-specific DNA binding; cytosol; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment; positive regulation of transcription from RNA polymerase II promoter in response to acidity; positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; positive regulation of transcription from RNA polymerase II promoter in response to ethanol; positive regulation of transcription from RNA polymerase II promoter in response to freezing; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation; positive regulation of transcription from RNA polymerase II promoter in response to heat stress; positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide; positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure; positive regulation of transcription from RNA polymerase II promoter in response to increased salt; positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction; replicative cell aging,PF00096;,,,,,,,,,MSN4_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; cellular response to acidic pH [GO:0071468]; chromatin remodeling [GO:0006338]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [GO:0061401]; positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [GO:0061422]; positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [GO:0061412]; positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [GO:0061395]; positive regulation of transcription from RNA polymerase II promoter in response to cold [GO:0061411]; positive regulation of transcription from RNA polymerase II promoter in response to ethanol [GO:0061410]; positive regulation of transcription from RNA polymerase II promoter in response to freezing [GO:0061409]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [GO:0061407]; positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [GO:0061405]; positive regulation of transcription from RNA polymerase II promoter in response to increased salt [GO:0061404]; positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [GO:0061403]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [GO:0061434]; replicative cell aging [GO:0001302]; transcription, DNA-templated [GO:0006351]" comp20620_c0_seq1,281,40.9253,0.71078405,2,23,,3.00E-17,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp20645_c0_seq1,385,42.8571,1.09889863,14,25,,6.00E-27,Q96I34,Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase-targeting subunit 3),Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase-targeting subunit 3),GO:0005886,plasma membrane,PF12796;,9.00E-31,CHOYP_LOC581083.1.1,,,,,,,PP16A_HUMAN,Homo sapiens (Human), comp20646_c0_seq1,339,40.708,0.86349958,15,12,,6.00E-06,P05617,Ovomucoid (Fragment),Ovomucoid (Fragment),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,IOVO_DACNO,Dacelo novaeguineae (Laughing kookaburra) (Dacelo gigas), comp20647_c0_seq1,1176,48.1293,0.75254865,68,20,,5.00E-56,P29957,"Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)","Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)",GO:0004556; GO:0005975; GO:0046872,alpha-amylase activity; carbohydrate metabolic process; metal ion binding,PF00128;PF02806;,3.00E-61,CHOYP_LOC587610.3.3,1.00E-46,ruditapes_c7745,,,,,AMY_PSEHA,Pseudoalteromonas haloplanktis (Alteromonas haloplanktis),carbohydrate metabolic process [GO:0005975] comp20662_c0_seq1,814,35.258,0.43868729,63,9,,9.00E-50,Q8BSL4,Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5),Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5),GO:0000139; GO:0008467; GO:0015015; GO:0016021; GO:0050819; GO:0006477; GO:0046596,"Golgi membrane; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; integral to membrane; negative regulation of coagulation; protein sulfation; regulation of viral entry into host cell",PF00685;,,,,,,,,,HS3S5_MOUSE,Mus musculus (Mouse),"heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]" comp20700_c0_seq1,263,47.9087,0.93146508,6,12,,1.00E-21,Q8TBF8,Protein FAM81A,Protein FAM81A,,,,4.00E-27,CHOYP_BRAFLDRAFT_98567.1.2,,,,,,,FA81A_HUMAN,Homo sapiens (Human), comp20708_c0_seq1,232,39.6552,1.10167531,2,15,,1.00E-11,P30559,Oxytocin receptor (OT-R),Oxytocin receptor (OT-R),GO:0070371; GO:0016324; GO:0005913; GO:0048565; GO:0042755; GO:0007204; GO:0060206; GO:0007565; GO:0007507; GO:0005887; GO:0007595; GO:0042711; GO:0060137; GO:0007613; GO:0005902; GO:0006936; GO:0060455; GO:0004990; GO:0017046; GO:0045777; GO:0010701; GO:0060406; GO:0051965; GO:0032230; GO:0051968; GO:0070474; GO:0001975; GO:0034059; GO:0042220; GO:0034097; GO:0042493; GO:0032355; GO:0043434; GO:0032570; GO:0030431; GO:0035176; GO:0042713; GO:0001967; GO:0021537; GO:0005000,"ERK1 and ERK2 cascade; apical plasma membrane; cell-cell adherens junction; digestive tract development; eating behavior; elevation of cytosolic calcium ion concentration; estrous cycle phase; female pregnancy; heart development; integral to plasma membrane; lactation; maternal behavior; maternal process involved in parturition; memory; microvillus; muscle contraction; negative regulation of gastric acid secretion; oxytocin receptor activity; peptide hormone binding; positive regulation of blood pressure; positive regulation of norepinephrine secretion; positive regulation of penile erection; positive regulation of synapse assembly; positive regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, glutamatergic; positive regulation of uterine smooth muscle contraction; response to amphetamine; response to anoxia; response to cocaine; response to cytokine stimulus; response to drug; response to estradiol stimulus; response to peptide hormone stimulus; response to progesterone stimulus; sleep; social behavior; sperm ejaculation; suckling behavior; telencephalon development; vasopressin receptor activity",PF00001;,,,,,,,,,OXYR_HUMAN,Homo sapiens (Human),"cell surface receptor signaling pathway [GO:0007166]; cellular response to hormone stimulus [GO:0032870]; digestive tract development [GO:0048565]; eating behavior [GO:0042755]; ERK1 and ERK2 cascade [GO:0070371]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; heart development [GO:0007507]; lactation [GO:0007595]; maternal behavior [GO:0042711]; maternal process involved in parturition [GO:0060137]; memory [GO:0007613]; muscle contraction [GO:0006936]; negative regulation of gastric acid secretion [GO:0060455]; positive regulation of blood pressure [GO:0045777]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of norepinephrine secretion [GO:0010701]; positive regulation of penile erection [GO:0060406]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vasoconstriction [GO:0045907]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; response to amphetamine [GO:0001975]; response to anoxia [GO:0034059]; response to cocaine [GO:0042220]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to peptide [GO:1901652]; response to peptide hormone [GO:0043434]; response to progesterone [GO:0032570]; sleep [GO:0030431]; social behavior [GO:0035176]; sperm ejaculation [GO:0042713]; suckling behavior [GO:0001967]; telencephalon development [GO:0021537]" comp20716_c0_seq1,208,43.75,0.81562861,7,11,,4.00E-10,Q07075,Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),GO:0001525; GO:0002005; GO:0002003; GO:0016324; GO:0005903; GO:0016477; GO:0008283; GO:0007267; GO:0044267; GO:0031410; GO:0009897; GO:0032835; GO:0005887; GO:0005765; GO:0070006; GO:0006508; GO:0008270,angiogenesis; angiotensin catabolic process in blood; angiotensin maturation; apical plasma membrane; brush border; cell migration; cell proliferation; cell-cell signaling; cellular protein metabolic process; cytoplasmic vesicle; external side of plasma membrane; glomerulus development; integral to plasma membrane; lysosomal membrane; metalloaminopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPE_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] comp20717_c0_seq1,257,48.249,0.73849674,3,21,,6.00E-09,Q92887,Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2),Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2),GO:0005524; GO:0042626; GO:0016324; GO:0030644; GO:0006855; GO:0005887; GO:0046581; GO:0008514; GO:0015732; GO:0046685; GO:0009408; GO:0031427; GO:0006979; GO:0070327,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; apical plasma membrane; cellular chloride ion homeostasis; drug transmembrane transport; integral to plasma membrane; intercellular canaliculus; organic anion transmembrane transporter activity; prostaglandin transport; response to arsenic-containing substance; response to heat; response to methotrexate; response to oxidative stress; thyroid hormone transport",PF00664;PF00005;,,,,,,,,,MRP2_HUMAN,Homo sapiens (Human),cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp20736_c0_seq1,371,44.2049,0.39011519,8,26,,4.00E-11,Q3U829,AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5),AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5),GO:0044599; GO:0005737; GO:0000724; GO:0016197; GO:0005730; GO:0005634; GO:0015031,AP-5 adaptor complex; cytoplasm; double-strand break repair via homologous recombination; endosomal transport; nucleolus; nucleus; protein transport,PF14764;,2.00E-13,CHOYP_BRAFLDRAFT_117560.1.1,,,,,,,AP5Z1_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031] comp20791_c0_seq1,325,35.3846,0.51355244,9,23,,4.00E-16,Q14CX7,"N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120)","N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120)",GO:0005737,cytoplasm,PF09797;,,,,,,,,,NAA25_HUMAN,Homo sapiens (Human),N-terminal peptidyl-methionine acetylation [GO:0017196] comp20804_c0_seq1,251,43.4263,0.88796335,3,17,,1.00E-15,Q29AK2,Leishmanolysin-like peptidase (EC 3.4.24.-),Leishmanolysin-like peptidase (EC 3.4.24.-),GO:0007420; GO:0007155; GO:0051301; GO:0051298; GO:0006338; GO:0005737; GO:0008354; GO:0008406; GO:0007444; GO:0016020; GO:0046872; GO:0004222; GO:0007100; GO:0007076; GO:0007052; GO:0008233; GO:0045842; GO:0006508,brain development; cell adhesion; cell division; centrosome duplication; chromatin remodeling; cytoplasm; germ cell migration; gonad development; imaginal disc development; membrane; metal ion binding; metalloendopeptidase activity; mitotic centrosome separation; mitotic chromosome condensation; mitotic spindle organization; peptidase activity; positive regulation of mitotic metaphase/anaphase transition; proteolysis,PF01457;,,,,,,,,,LMLN_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842] comp20811_c0_seq1,670,40.4478,0.40443926,16,37,,4.00E-59,Q5T3F8,Transmembrane protein 63B,CSC1-like protein 2 (Transmembrane protein 63B),GO:0016021; GO:0000166,integral to membrane; nucleotide binding,PF14703;PF02714;PF13967;,2.00E-48,CHOYP_contig_009370,,,,,,,TM63B_HUMAN,Homo sapiens (Human),ion transport [GO:0006811] comp20836_c0_seq1,306,45.7516,0.70354918,8,0,,1.00E-09,Q9BYK8,"Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)","Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)",GO:0005524; GO:0003677; GO:0044255; GO:0004386; GO:0030374; GO:0046872; GO:0005654; GO:0045944; GO:0044281; GO:0006351,"ATP binding; DNA binding; cellular lipid metabolic process; helicase activity; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; transcription, DNA-dependent",,,,,,,,,,PR285_HUMAN,Homo sapiens (Human),"cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp20843_c0_seq1,239,45.1883,0.6593522,4,16,,5.00E-15,O35099,Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),GO:0005524; GO:0007254; GO:0004709; GO:0000187; GO:0070301; GO:0008656; GO:0005783; GO:0045087; GO:0008631; GO:0000287; GO:0043065; GO:0042803,ATP binding; JNK cascade; MAP kinase kinase kinase activity; activation of MAPK activity; cellular response to hydrogen peroxide; cysteine-type endopeptidase activator activity involved in apoptotic process; endoplasmic reticulum; innate immune response; intrinsic apoptotic signaling pathway in response to oxidative stress; magnesium ion binding; positive regulation of apoptotic process; protein homodimerization activity,PF13281;PF00069;,,,,,,,,,M3K5_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931] comp20854_c0_seq1,202,42.0792,0.33721757,3,13,,8.00E-12,Q9QZ48,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein),GO:0003677; GO:0030154; GO:0035035; GO:0046872; GO:0007275; GO:0045892; GO:0005634; GO:0045670; GO:0003700; GO:0006351,"DNA binding; cell differentiation; histone acetyltransferase binding; metal ion binding; multicellular organismal development; negative regulation of transcription, DNA-dependent; nucleus; regulation of osteoclast differentiation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp20854_c1_seq1,225,37.7778,0.50111855,3,1,,8.00E-12,Q9QZP2,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0071363; GO:0031670; GO:0005829; GO:0046872; GO:0008168; GO:0030308; GO:0005654; GO:0006355; GO:0006351,"DNA binding; cellular response to growth factor stimulus; cellular response to nutrient; cytosol; metal ion binding; methyltransferase activity; negative regulation of cell growth; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_RAT,Rattus norvegicus (Rat),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp20875_c0_seq1,259,38.9961,0.61225403,4,15,,2.00E-14,O75382,Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97),GO:0005737; GO:0005769; GO:0007399; GO:0008022; GO:0015031; GO:0008270,cytoplasm; early endosome; nervous system development; protein C-terminus binding; protein transport; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM3_HUMAN,Homo sapiens (Human),nervous system development [GO:0007399]; protein transport [GO:0015031] comp20884_c0_seq1,442,49.5475,0.83671445,0,58,,5.00E-28,P30306,M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B),M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B),GO:0051301; GO:0005813; GO:0005737; GO:0007144; GO:0007067; GO:0005634; GO:0001556; GO:0035335; GO:0032467; GO:0045931; GO:0045860; GO:0006468; GO:0004725; GO:0000922,cell division; centrosome; cytoplasm; female meiosis I; mitosis; nucleus; oocyte maturation; peptidyl-tyrosine dephosphorylation; positive regulation of cytokinesis; positive regulation of mitotic cell cycle; positive regulation of protein kinase activity; protein phosphorylation; protein tyrosine phosphatase activity; spindle pole,PF06617;PF00581;,2.00E-28,CHOYP_LOC100561262.1.1,,,,,,,MPIP2_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; female meiosis I [GO:0007144]; mitotic nuclear division [GO:0007067]; oocyte maturation [GO:0001556]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468] comp20919_c0_seq1,203,41.3793,0.35012291,0,0,,9.00E-06,Q969K4,Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein),Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein),GO:0005737; GO:0005730; GO:0005886; GO:0003746,cytoplasm; nucleolus; plasma membrane; translation elongation factor activity,PF12796;PF00651;,,,,,,,,,ABTB1_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp20920_c1_seq1,622,39.3891,0.62283552,15,44,,2.00E-25,Q9UJN7,Zinc finger protein 391,Zinc finger protein 391,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN391_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp20927_c0_seq1,567,40.2116,0.80918336,7,28,,3.00E-49,Q96PH1,NADPH oxidase 5 (EC 1.6.3.-),NADPH oxidase 5 (EC 1.6.3.-),GO:0050661; GO:0001525; GO:0006915; GO:0005509; GO:0050663; GO:0000910; GO:0005783; GO:0001935; GO:0050660; GO:0020037; GO:0015252; GO:0016021; GO:2000379; GO:0043012; GO:0010155; GO:0042554; GO:0016175,NADP binding; angiogenesis; apoptotic process; calcium ion binding; cytokine secretion; cytokinesis; endoplasmic reticulum; endothelial cell proliferation; flavin adenine dinucleotide binding; heme binding; hydrogen ion channel activity; integral to membrane; positive regulation of reactive oxygen species metabolic process; regulation of fusion of sperm to egg plasma membrane; regulation of proton transport; superoxide anion generation; superoxide-generating NADPH oxidase activity,PF13202;PF13405;PF08022;PF01794;PF08030;,6.00E-29,CHOYP_TRIADDRAFT_29444.1.2,,,,,,,NOX5_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; cytokine secretion [GO:0050663]; cytokinesis [GO:0000910]; endothelial cell proliferation [GO:0001935]; oxidation-reduction process [GO:0055114]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of fusion of sperm to egg plasma membrane [GO:0043012]; regulation of proton transport [GO:0010155]; response to reactive oxygen species [GO:0000302]; superoxide anion generation [GO:0042554] comp20929_c0_seq1,212,38.2075,0.52335317,0,24,,2.00E-08,Q7JQD3,Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1),Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1),GO:0003779; GO:0051693; GO:0030043; GO:0030041; GO:0051014; GO:0045010; GO:0005509; GO:0005737; GO:0005856; GO:0007275,actin binding; actin filament capping; actin filament fragmentation; actin filament polymerization; actin filament severing; actin nucleation; calcium ion binding; cytoplasm; cytoskeleton; multicellular organismal development,PF00626;,5.00E-18,CHOYP_GELS2.2.2,,,,,,,GELS1_LUMTE,Lumbricus terrestris (Common earthworm),actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; multicellular organism development [GO:0007275] comp20942_c0_seq1,547,41.1335,0.8668172,44,0,,1.00E-07,Q69Z37,Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like),,,,,,,,,,,,SAM9L_MOUSE,Mus musculus (Mouse),common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145] comp20959_c0_seq1,440,42.2727,0.36780841,12,21,,8.00E-43,Q54BU4,ABC transporter B family member 1 (ABC transporter ABCB.1),ABC transporter B family member 1 (ABC transporter ABCB.1),GO:0005524; GO:0043190; GO:0006935; GO:0031154; GO:0006972; GO:0016021; GO:0005739; GO:0015421; GO:0005886,ATP binding; ATP-binding cassette (ABC) transporter complex; chemotaxis; culmination involved in sorocarp development; hyperosmotic response; integral to membrane; mitochondrion; oligopeptide-transporting ATPase activity; plasma membrane,PF00664;PF00005;,5.00E-47,CHOYP_BRAFLDRAFT_84327.2.2,,,,,,,ABCB1_DICDI,Dictyostelium discoideum (Slime mold),chemotaxis [GO:0006935]; culmination involved in sorocarp development [GO:0031154]; hyperosmotic response [GO:0006972]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp20963_c0_seq1,265,47.9245,1.45212986,1,20,,1.00E-06,Q99487,"Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (SD-PLA2) (hSD-PLA2)","Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (SD-PLA2) (hSD-PLA2)",GO:0003847; GO:0005737; GO:0016042; GO:0006629; GO:0043066; GO:0005543,1-alkyl-2-acetylglycerophosphocholine esterase activity; cytoplasm; lipid catabolic process; lipid metabolic process; negative regulation of apoptotic process; phospholipid binding,PF03403;,,,,,,,,,PAFA2_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066] comp20969_c0_seq1,464,45.6897,0.24866426,8,26,,3.00E-14,Q9WTN6,Solute carrier family 22 member 21 (Organic cation/carnitine transporter 3) (Solute carrier family 22 member 9),Solute carrier family 22 member 21 (Organic cation/carnitine transporter 3) (Solute carrier family 22 member 9),GO:0005524; GO:0015226; GO:0016021; GO:0031231,ATP binding; carnitine transmembrane transporter activity; integral to membrane; intrinsic to peroxisomal membrane,PF00083;,6.00E-15,CHOYP_BRAFLDRAFT_75990.1.1,,,,,,,S22AL_MOUSE,Mus musculus (Mouse),carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879] comp20974_c0_seq1,202,65.8416,1.07781958,0,18,,4.00E-17,Q9LRB8,60S ribosomal protein L36,60S ribosomal protein L36,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01158;,,,,,,,,,RL36_ENTCP,Ulva compressa (Green alga) (Enteromorpha compressa),translation [GO:0006412] comp20978_c0_seq1,235,49.3617,0.91447259,1,18,,2.00E-06,Q9Z111,Growth arrest and DNA damage-inducible protein GADD45 gamma (Cytokine-responsive protein CR6),Growth arrest and DNA damage-inducible protein GADD45 gamma (Cytokine-responsive protein CR6),GO:0045063; GO:0000186; GO:0006915; GO:0042095; GO:0006469; GO:0005634; GO:0051726; GO:0006950,T-helper 1 cell differentiation; activation of MAPKK activity; apoptotic process; interferon-gamma biosynthetic process; negative regulation of protein kinase activity; nucleus; regulation of cell cycle; response to stress,PF01248;,,,,,,,,,GA45G_MOUSE,Mus musculus (Mouse),activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; interferon-gamma biosynthetic process [GO:0042095]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950]; T-helper 1 cell differentiation [GO:0045063] comp20984_c0_seq1,236,63.9831,0.87779354,0,23,,5.00E-07,P10346,Glutamine transport ATP-binding protein GlnQ,Glutamine transport ATP-binding protein GlnQ,GO:0005524; GO:0006200; GO:0016887; GO:0006865; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; amino acid transport; plasma membrane,PF00005;,,,,,,,,,GLNQ_ECOLI,Escherichia coli (strain K12), comp20990_c0_seq1,257,40.0778,0.68410127,8,15,,8.00E-12,Q6ZQE4,Transmembrane protein 194A,Nuclear envelope integral membrane protein 1,GO:0016021,integral to membrane,PF10225;,,,,,,,,,T194A_MOUSE,Mus musculus (Mouse), comp21004_c0_seq1,445,40.2247,0.53821672,7,28,,1.00E-71,Q8BU31,Ras-related protein Rap-2c,Ras-related protein Rap-2c,GO:0005525; GO:0003924; GO:0032486; GO:0005829; GO:0030336; GO:0031954; GO:0055038; GO:0061097,GTP binding; GTPase activity; Rap protein signal transduction; cytosol; negative regulation of cell migration; positive regulation of protein autophosphorylation; recycling endosome membrane; regulation of protein tyrosine kinase activity,PF00071;,1.00E-79,CHOYP_LOC100168751.1.1,,,,,,,RAP2C_MOUSE,Mus musculus (Mouse),establishment of endothelial intestinal barrier [GO:0090557]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; Rap protein signal transduction [GO:0032486]; regulation of protein tyrosine kinase activity [GO:0061097] comp21014_c0_seq1,370,39.1892,0.70748038,9,24,,3.00E-13,Q6ZNA1,Zinc finger protein 836,Zinc finger protein 836,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN836_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp21023_c0_seq1,323,44.2724,0.89257054,6,14,,2.00E-25,Q62773,Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (rCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2),Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (rCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2),GO:0016021; GO:0001882; GO:0005415; GO:0034394; GO:0001895,integral to membrane; nucleoside binding; nucleoside:sodium symporter activity; protein localization to cell surface; retina homeostasis,PF07670;PF07662;PF01773;,8.00E-12,CHOYP_SLC28A3.1.1,,,,,,,S28A2_RAT,Rattus norvegicus (Rat),protein localization to cell surface [GO:0034394]; purine nucleoside transmembrane transport [GO:0015860]; retina homeostasis [GO:0001895] comp21036_c0_seq1,259,59.4595,1.09928918,0,26,,7.00E-22,O33915,Citrate synthase (EC 2.3.3.1),Citrate synthase (EC 2.3.3.16),GO:0044262; GO:0004108; GO:0005737; GO:0006099,cellular carbohydrate metabolic process; citrate (Si)-synthase activity; cytoplasm; tricarboxylic acid cycle,PF00285;,,,,,,,,,CISY_RHIME,Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti),tricarboxylic acid cycle [GO:0006099] comp21050_c0_seq1,202,44.0594,1.04105115,0,17,,5.00E-11,Q8C4U2,Transmembrane protein 145,Transmembrane protein 145,GO:0007186; GO:0016021; GO:0019236,G-protein coupled receptor signaling pathway; integral to membrane; response to pheromone,PF10192;,,,,,,,,,TM145_MOUSE,Mus musculus (Mouse),G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] comp21056_c0_seq1,218,43.578,0.68134767,0,11,,2.00E-14,Q9H8U3,AN1-type zinc finger protein 3 (Testis-expressed sequence 27),AN1-type zinc finger protein 3 (Testis-expressed sequence 27),GO:0003677; GO:0008270,DNA binding; zinc ion binding,PF01754;PF01428;,,,,,,,,,ZFAN3_HUMAN,Homo sapiens (Human), comp21080_c0_seq1,464,43.319,0.55555814,17,18,,5.00E-62,Q15811,Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17),GO:0005089; GO:0097190; GO:0005509; GO:0030054; GO:0005905; GO:0005829; GO:0030139; GO:0005085; GO:0019209; GO:0030027; GO:0043524; GO:0043005; GO:0048011; GO:0005543; GO:0005886; GO:0043065; GO:0051897; GO:0032947; GO:0035023; GO:0051056; GO:0007264; GO:0045202; GO:0048488,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; calcium ion binding; cell junction; coated pit; cytosol; endocytic vesicle; guanyl-nucleotide exchange factor activity; kinase activator activity; lamellipodium; negative regulation of neuron apoptotic process; neuron projection; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; positive regulation of apoptotic process; positive regulation of protein kinase B signaling cascade; protein complex scaffold; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; synapse; synaptic vesicle endocytosis,PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;,4.00E-43,CHOYP_ITSN1.1.4,,,,,,,ITSN1_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488] comp21086_c0_seq1,1051,45.4805,0.97301808,33,27,,8.00E-36,P29617,Homeobox protein prospero,Homeobox protein prospero,GO:0003677; GO:0007465; GO:0001078; GO:0045179; GO:0008356; GO:0055060; GO:0007411; GO:0060385; GO:0045180; GO:0007420; GO:0001708; GO:0042676; GO:0070983; GO:0007402; GO:0010001; GO:0008049; GO:0005875; GO:0050771; GO:0007406; GO:0007400; GO:0005634; GO:0007422; GO:0006909; GO:0005886; GO:0010628; GO:0008104; GO:0045676; GO:1900180; GO:0042673; GO:0050909; GO:0007416; GO:0007419,DNA binding; R7 cell fate commitment; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; apical cortex; asymmetric cell division; asymmetric neuroblast division resulting in ganglion mother cell formation; axon guidance; axonogenesis involved in innervation; basal cortex; brain development; cell fate specification; compound eye cone cell fate commitment; dendrite guidance; ganglion mother cell fate determination; glial cell differentiation; male courtship behavior; microtubule associated complex; negative regulation of axonogenesis; negative regulation of neuroblast proliferation; neuroblast fate determination; nucleus; peripheral nervous system development; phagocytosis; plasma membrane; positive regulation of gene expression; protein localization; regulation of R7 cell differentiation; regulation of protein localization to nucleus; regulation of retinal cone cell fate specification; sensory perception of taste; synapse assembly; ventral cord development,PF05044;,1.00E-59,CHOYP_ISCW_ISCW008733.1.1,,,,,,,PROS_DROME,Drosophila melanogaster (Fruit fly),"asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; compound eye cone cell fate commitment [GO:0042676]; courtship behavior [GO:0007619]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; eye photoreceptor cell differentiation [GO:0001754]; G1 to G0 transition [GO:0070314]; ganglion mother cell fate determination [GO:0007402]; glial cell differentiation [GO:0010001]; male courtship behavior [GO:0008049]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; R7 cell fate commitment [GO:0007465]; regulation of neuron differentiation [GO:0045664]; regulation of protein localization to nucleus [GO:1900180]; regulation of R7 cell differentiation [GO:0045676]; regulation of retinal cone cell fate specification [GO:0042673]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ development [GO:0007423]; sensory perception of taste [GO:0050909]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp21089_c0_seq1,514,40.856,0.4796963,16,11,,4.00E-18,P0C0T2,Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6),Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6),GO:0005737; GO:0042803,cytoplasm; protein homodimerization activity,PF12796;PF13606;PF00536;,2.00E-27,CHOYP_LOC100378344.1.1,,,,,,,ANKS6_RAT,Rattus norvegicus (Rat), comp21113_c0_seq1,345,50.1449,0.53894534,14,9,,4.00E-18,Q8N0X7,Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1),Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1),GO:0009838; GO:0060612; GO:0008219; GO:0051301; GO:0000910; GO:0005811; GO:0034389; GO:0030496; GO:0005741; GO:0030514; GO:0048698; GO:0050905; GO:0051881; GO:0045202,abscission; adipose tissue development; cell death; cell division; cytokinesis; lipid particle; lipid particle organization; midbody; mitochondrial outer membrane; negative regulation of BMP signaling pathway; negative regulation of collateral sprouting in absence of injury; neuromuscular process; regulation of mitochondrial membrane potential; synapse,PF06911;,2.00E-13,CHOYP_LOC100892454.1.1,,,,,,,SPG20_HUMAN,Homo sapiens (Human),abscission [GO:0009838]; adipose tissue development [GO:0060612]; cell division [GO:0051301]; lipid particle organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881] comp21127_c0_seq1,793,47.0366,0.52504252,22,12,,1.00E-15,P68500,Contactin-5 (Neural recognition molecule NB-2),Contactin-5 (Neural recognition molecule NB-2),GO:0031225; GO:0007155; GO:0005737; GO:0005886; GO:0007605,anchored to membrane; cell adhesion; cytoplasm; plasma membrane; sensory perception of sound,PF00041;PF07679;,,,,,,,,,CNTN5_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605] comp21164_c0_seq1,205,48.7805,0.74910873,3,16,,1.00E-06,Q5VWJ9,Sorting nexin-30,Sorting nexin-30,GO:0007154; GO:0005737; GO:0035091; GO:0015031,cell communication; cytoplasm; phosphatidylinositol binding; protein transport,PF03114;PF00787;,,,,,,,,,SNX30_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle organization [GO:0016050] comp21166_c0_seq1,267,64.0449,1.18226086,0,21,,4.00E-07,Q04304,UPF0659 protein YMR090W,UPF0659 protein YMR090W,GO:0005737,cytoplasm,PF13460;,,,,,,,,,YMY0_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp21191_c0_seq1,264,45.8333,0.50767012,8,16,,9.00E-16,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp21198_c0_seq1,218,50.9174,0.21331618,1,15,,3.00E-10,Q8TGB2,GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Glycosylphosphatidylinositol-anchor biosynthesis protein 7),GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Glycosylphosphatidylinositol-anchor biosynthesis protein 7),GO:0006506; GO:0006505; GO:0009267; GO:0005789; GO:0036180; GO:0036170; GO:0016021; GO:0009405; GO:0016740,GPI anchor biosynthetic process; GPI anchor metabolic process; cellular response to starvation; endoplasmic reticulum membrane; filamentous growth of a population of unicellular organisms in response to biotic stimulus; filamentous growth of a population of unicellular organisms in response to starvation; integral to membrane; pathogenesis; transferase activity,PF01663;,,,,,,,,,GPI7_CANAL,Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast),GPI anchor biosynthetic process [GO:0006506] comp21218_c0_seq1,417,51.3189,0.55349895,11,14,,3.00E-32,P0C0T2,Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6),Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6),GO:0005737; GO:0042803,cytoplasm; protein homodimerization activity,PF12796;PF13606;PF00536;,2.00E-13,CHOYP_LOC100378344.1.1,,,,,,,ANKS6_RAT,Rattus norvegicus (Rat), comp21222_c0_seq1,669,40.9567,0.40122034,12,33,,2.00E-12,O96838,Putative 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (Type III PIP kinase) (PIPkin-III),Putative 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (Type III PIP kinase) (PIPkin-III),GO:0000285; GO:0016308; GO:0005524; GO:0044267; GO:0005768; GO:0010008; GO:0008333; GO:0035556; GO:0012506; GO:0008270,1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; cellular protein metabolic process; endosome; endosome membrane; endosome to lysosome transport; intracellular signal transduction; vesicle membrane; zinc ion binding,PF00118;PF01363;PF01504;,,,,,,,,,FYV1_DROME,Drosophila melanogaster (Fruit fly),autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular signal transduction [GO:0035556]; phosphatidylinositol phosphorylation [GO:0046854]; phosphorylation [GO:0016310] comp21224_c0_seq1,226,51.3274,0.54129227,0,17,,9.00E-08,O54990,Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133),Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133),GO:0016324; GO:0005903; GO:0060219; GO:0009986; GO:0005615; GO:0005887; GO:0031528; GO:0001750; GO:0071914; GO:0010842; GO:0032420,apical plasma membrane; brush border; camera-type eye photoreceptor cell differentiation; cell surface; extracellular space; integral to plasma membrane; microvillus membrane; photoreceptor outer segment; prominosome; retina layer formation; stereocilium,PF05478;,,,,,,,,,PROM1_MOUSE,Mus musculus (Mouse),camera-type eye photoreceptor cell differentiation [GO:0060219]; glomerular parietal epithelial cell differentiation [GO:0072139]; glomerular visceral epithelial cell differentiation [GO:0072112]; photoreceptor cell maintenance [GO:0045494]; positive regulation of nephron tubule epithelial cell differentiation [GO:2000768]; retina layer formation [GO:0010842]; retina morphogenesis in camera-type eye [GO:0060042] comp21226_c0_seq1,304,44.0789,1.24069139,0,27,,6.00E-06,P51663,"Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)","Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)",GO:0020037; GO:0005506; GO:0031966; GO:0004507; GO:0006694,heme binding; iron ion binding; mitochondrial membrane; steroid 11-beta-monooxygenase activity; steroid biosynthetic process,PF00067;,,,,,,,,,C11B1_SHEEP,Ovis aries (Sheep),steroid biosynthetic process [GO:0006694] comp21230_c0_seq1,364,45.8791,0.42840699,20,6,,3.00E-44,O13914,Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS),GO:0005524; GO:0004813; GO:0006419; GO:0005829; GO:0046872; GO:0032543; GO:0005739; GO:0000049,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; cytosol; metal ion binding; mitochondrial translation; mitochondrion; tRNA binding,PF02272;PF01411;PF07973;,9.00E-12,CHOYP_SYAC.1.2,,,,,,,SYA_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),alanyl-tRNA aminoacylation [GO:0006419]; cytoplasmic alanyl-tRNA aminoacylation [GO:1990762]; mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; tRNA modification [GO:0006400] comp21266_c0_seq1,276,63.7681,0.8265547,0,20,,3.00E-55,Q6A7V6,Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS),Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS),GO:0005524; GO:0005737; GO:0000287; GO:0004826; GO:0006432; GO:0000049; GO:0008033,ATP binding; cytoplasm; magnesium ion binding; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding; tRNA processing,PF03483;PF03484;PF03147;PF01588;,,,,,,,,,SYFB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033] comp21293_c0_seq1,217,47.0046,0.25627503,6,16,,3.00E-25,P14410,"Sucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)]","Sucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)]",GO:0005794; GO:0016324; GO:0005903; GO:0030246; GO:0005975; GO:0016021; GO:0004574; GO:0005886; GO:0044245; GO:0044281; GO:0004575,"Golgi apparatus; apical plasma membrane; brush border; carbohydrate binding; carbohydrate metabolic process; integral to membrane; oligo-1,6-glucosidase activity; plasma membrane; polysaccharide digestion; small molecule metabolic process; sucrose alpha-glucosidase activity",PF01055;PF16863;PF00088;,,,,,,,,,SUIS_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245] comp21302_c0_seq1,287,34.1463,0.96604946,1,20,,2.00E-08,Q9DD78,Toll-like receptor 2 type-1,Toll-like receptor 2 type-1,GO:0002755; GO:0006954; GO:0045087; GO:0016021; GO:0005886; GO:0050729; GO:0050707; GO:0002237; GO:0035681; GO:0034134; GO:0034142; GO:0034146; GO:0004888,MyD88-dependent toll-like receptor signaling pathway; inflammatory response; innate immune response; integral to membrane; plasma membrane; positive regulation of inflammatory response; regulation of cytokine secretion; response to molecule of bacterial origin; toll-like receptor 15 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; transmembrane signaling receptor activity,PF13855;PF01582;,,,,,,,,,TLR21_CHICK,Gallus gallus (Chicken),inflammatory response [GO:0006954]; innate immune response [GO:0045087]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor signaling pathway [GO:0002224] comp21334_c0_seq1,261,46.3602,0.859029,0,14,,2.00E-22,Q80WQ4,Putative methyltransferase KIAA1456 (EC 2.1.1.-),Probable tRNA methyltransferase 9-like protein (TRM9L) (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF08241;,2.00E-18,CHOYP_K1456.1.1,,,,,,,K1456_MOUSE,Mus musculus (Mouse),tRNA wobble uridine modification [GO:0002098] comp21338_c0_seq1,257,45.1362,0.38450657,3,19,,4.00E-23,O14657,Torsin-1B (Torsin family 1 member B),Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B),GO:0005524; GO:0051085; GO:0005788; GO:0005635; GO:0071763; GO:0017111; GO:0051260; GO:0006986; GO:0051082,ATP binding; chaperone mediated protein folding requiring cofactor; endoplasmic reticulum lumen; nuclear envelope; nuclear membrane organization; nucleoside-triphosphatase activity; protein homooligomerization; response to unfolded protein; unfolded protein binding,PF06309;,5.00E-13,CHOYP_BRAFLDRAFT_128102.1.1,,,,,,,TOR1B_HUMAN,Homo sapiens (Human),chaperone mediated protein folding requiring cofactor [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein homooligomerization [GO:0051260]; response to unfolded protein [GO:0006986] comp21377_c0_seq1,431,40.1392,0.36923276,2,0,,4.00E-24,Q14112,Nidogen-2 (NID-2) (Osteonidogen),Nidogen-2 (NID-2) (Osteonidogen),GO:0005604; GO:0005509; GO:0007155; GO:0009986; GO:0007160; GO:0005518,basement membrane; calcium ion binding; cell adhesion; cell surface; cell-matrix adhesion; collagen binding,PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;,,,,,,,,,NID2_HUMAN,Homo sapiens (Human),basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198] comp21377_c0_seq2,478,43.0962,0.28385309,2,11,,2.00E-72,O75581,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0034185; GO:0090245; GO:0060349; GO:0046849; GO:0060444; GO:0061310; GO:0044335; GO:0061324; GO:0044340; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0021987; GO:0060026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0030326; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:0005886; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0045598; GO:0030278; GO:0051593; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; apolipoprotein binding; axis elongation involved in somitogenesis; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; canonical Wnt receptor signaling pathway involved in regulation of cell proliferation; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; cerebral cortex development; convergent extension; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic limb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; plasma membrane; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; regulation of fat cell differentiation; regulation of ossification; response to folic acid; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,4.00E-30,CHOYP_LRP6.3.6,,,,,,,LRP6_HUMAN,Homo sapiens (Human),"axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; single organismal cell-cell adhesion [GO:0016337]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp21385_c0_seq1,302,38.7417,0.62530167,6,26,,6.00E-50,Q9WVS8,Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5),Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5),GO:0005524; GO:0004707; GO:0000165; GO:0016605; GO:0007049; GO:0030154; GO:0070301; GO:0071560; GO:0005829; GO:0051534; GO:0043066; GO:2000352; GO:2001240; GO:0034115; GO:1902176; GO:0060761; GO:0018105; GO:0051247; GO:0036003; GO:0004674; GO:0045765,ATP binding; MAP kinase activity; MAPK cascade; PML body; cell cycle; cell differentiation; cellular response to hydrogen peroxide; cellular response to transforming growth factor beta stimulus; cytosol; negative regulation of NFAT protein import into nucleus; negative regulation of apoptotic process; negative regulation of endothelial cell apoptotic process; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of heterotypic cell-cell adhesion; negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; negative regulation of response to cytokine stimulus; peptidyl-serine phosphorylation; positive regulation of protein metabolic process; positive regulation of transcription from RNA polymerase II promoter in response to stress; protein serine/threonine kinase activity; regulation of angiogenesis,PF00069;,1.00E-59,CHOYP_MAPK7.1.1,,,,,,,MK07_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK5 cascade [GO:0070377]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765] comp21387_c0_seq1,814,42.2604,0.96747534,7,62,,,,,,,,,,,3.00E-13,ruditapes_lrc7057,,,,,,, comp21391_c0_seq1,778,40.3599,0.73451521,24,18,,,,,,,,,,,4.00E-12,ruditapes_c4344,,,,,,, comp21415_c0_seq1,782,41.5601,0.41626862,13,43,,8.00E-52,Q58A42,Protein DD3-3,Protein DD3-3,GO:0016021,integral to membrane,,,,,,,,,,DD3_DICDI,Dictyostelium discoideum (Slime mold), comp21430_c0_seq1,332,38.5542,1.01114278,11,11,,2.00E-18,P25723,Dorsal-ventral patterning protein tolloid (EC 3.4.24.-),Dorsal-ventral patterning protein tolloid (EC 3.4.24.-),GO:0007378; GO:0005509; GO:0005576; GO:0008586; GO:0007313; GO:0004222; GO:0010629; GO:0030513; GO:0016485; GO:0006508; GO:0017015; GO:0007362; GO:0008293; GO:0008270,"amnioserosa formation; calcium ion binding; extracellular region; imaginal disc-derived wing vein morphogenesis; maternal specification of dorsal/ventral axis, oocyte, soma encoded; metalloendopeptidase activity; negative regulation of gene expression; positive regulation of BMP signaling pathway; protein processing; proteolysis; regulation of transforming growth factor beta receptor signaling pathway; terminal region determination; torso signaling pathway; zinc ion binding",PF01400;PF00431;PF07645;,,,,,,,,,TLD_DROME,Drosophila melanogaster (Fruit fly),"amnioserosa formation [GO:0007378]; embryonic pattern specification [GO:0009880]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; negative regulation of gene expression [GO:0010629]; positive regulation of BMP signaling pathway [GO:0030513]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; zygotic specification of dorsal/ventral axis [GO:0007352]" comp21444_c0_seq1,802,42.7681,0.55246044,0,5,,2.00E-06,P47137,Uncharacterized oxidoreductase YJR096W (EC 1.-.-.-),Uncharacterized oxidoreductase YJR096W (EC 1.-.-.-),GO:0042843; GO:0004032; GO:0019568; GO:0034599,D-xylose catabolic process; alditol:NADP+ 1-oxidoreductase activity; arabinose catabolic process; cellular response to oxidative stress,PF00248;,,,,,,,,,YJ66_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),arabinose catabolic process [GO:0019568]; cellular response to oxidative stress [GO:0034599]; D-xylose catabolic process [GO:0042843] comp21444_c0_seq2,875,42.8571,0.53023647,7,3,,4.00E-69,P48508,Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit),Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit),GO:0006534; GO:0006536; GO:0004357; GO:0035226; GO:0017109; GO:0006750; GO:0043524; GO:0035229; GO:0046982; GO:0050880; GO:0051900; GO:0042493; GO:0051409; GO:0006979,cysteine metabolic process; glutamate metabolic process; glutamate-cysteine ligase activity; glutamate-cysteine ligase catalytic subunit binding; glutamate-cysteine ligase complex; glutathione biosynthetic process; negative regulation of neuron apoptotic process; positive regulation of glutamate-cysteine ligase activity; protein heterodimerization activity; regulation of blood vessel size; regulation of mitochondrial depolarization; response to drug; response to nitrosative stress; response to oxidative stress,PF00248;,,,,,,,,,GSH0_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; hepatic stellate cell activation [GO:0035733]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of glutamate-cysteine ligase activity [GO:0035229]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to human chorionic gonadotropin [GO:0044752]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979] comp21449_c0_seq1,490,40.6122,0.7980529,18,30,,1.00E-16,Q33DR2,Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1),Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1),GO:0008299; GO:0046872; GO:0005739; GO:0046982; GO:0051290; GO:0000010; GO:0006744,isoprenoid biosynthetic process; metal ion binding; mitochondrion; protein heterodimerization activity; protein heterotetramerization; trans-hexaprenyltranstransferase activity; ubiquinone biosynthetic process,PF00348;,,,,,,,,,DPS1_MOUSE,Mus musculus (Mouse),isoprenoid biosynthetic process [GO:0008299]; protein heterotetramerization [GO:0051290]; ubiquinone biosynthetic process [GO:0006744] comp21464_c0_seq1,493,38.9452,0.56866816,12,39,,1.00E-27,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp21484_c0_seq2,254,36.6142,0.39802906,11,4,,1.00E-07,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp21512_c0_seq1,276,43.1159,0.63134732,9,13,,2.00E-12,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,8.00E-17,CHOYP_SACS.12.17,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp21526_c0_seq1,404,41.5842,0.45925157,7,31,,7.00E-28,Q80V23,Zinc finger protein 32 (Zinc finger protein 637),Zinc finger protein 32 (Zinc finger protein 637),GO:0046872; GO:0003676; GO:0005634,metal ion binding; nucleic acid binding; nucleus,PF00096;,2.00E-32,CHOYP_ZN226.2.2,,,,,,,ZNF32_MOUSE,Mus musculus (Mouse), comp21530_c0_seq1,235,41.2766,0.51755323,9,16,,5.00E-40,Q28HL3,Uncharacterized protein C15orf41 homolog,Uncharacterized protein C15orf41 homolog,,,PF14811;,1.00E-33,CHOYP_CO041.1.1,,,,,,,CO041_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp21534_c0_seq1,596,37.4161,0.43288875,25,12,,3.00E-18,Q99ML4,Protein FAM69B (Pancreatitis-induced protein 49),Protein FAM69B (Pancreatitis-induced protein 49),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF12260;PF14875;,,,,,,,,,FA69B_MOUSE,Mus musculus (Mouse), comp21555_c0_seq1,804,44.1542,0.30701802,28,36,,2.00E-67,Q80TI0,GRAM domain-containing protein 1B,GRAM domain-containing protein 1B,GO:0016021,integral to membrane,PF16016;PF02893;,6.00E-37,CHOYP_GRM1B.1.1,,,,,,,GRM1B_MOUSE,Mus musculus (Mouse), comp21561_c0_seq1,298,51.0067,0.9065556,3,27,,,,,,,,,5.00E-26,CHOYP_LOC100888944.1.1,,,,,,,,, comp21562_c0_seq1,214,47.6636,0.72392153,2,16,,3.00E-08,Q8C3L1,Protein SSUH2 homolog (Protein ssu-2 homolog),Protein SSUH2 homolog (Protein ssu-2 homolog),GO:0005737,cytoplasm,,,,,,,,,,CC032_MOUSE,Mus musculus (Mouse), comp21566_c0_seq1,257,60.7004,1.0179342,0,18,,1.00E-44,Q9FJX2,60S ribosomal protein L26-2,60S ribosomal protein L26-2,GO:0022625; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; structural constituent of ribosome; translation,PF00467;PF16906;,,,,,,,,,RL262_ARATH,Arabidopsis thaliana (Mouse-ear cress),cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273] comp21586_c0_seq1,719,49.5132,0.39030688,28,24,,1.00E-73,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,2.00E-105,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp21607_c0_seq1,341,47.2141,0.29081883,11,23,,4.00E-20,Q8R4C0,Calpain-5 (EC 3.4.22.-),Calpain-5 (EC 3.4.22.-),GO:0004198; GO:0009986; GO:0060014; GO:0005622; GO:0001553; GO:0001541; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; cell surface; granulosa cell differentiation; intracellular; luteinization; ovarian follicle development; proteolysis,PF01067;PF00648;,2.00E-25,CHOYP_CAN5.1.1,,,,,,,CAN5_RAT,Rattus norvegicus (Rat),granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508] comp21637_c0_seq1,379,41.6887,0.67019867,2,37,,6.00E-10,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp21652_c0_seq1,262,37.0229,0.45819483,7,12,,,,,,,,,,,4.00E-94,ruditapes_c1099,,,,,,, comp21667_c0_seq1,340,38.8235,0.24156053,4,28,,,,,,,,,1.00E-10,CHOYP_contig_039575,,,,,,,,, comp21672_c0_seq1,255,43.9216,0.16982019,13,15,,2.00E-19,P49256,Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36),Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36),GO:0000139; GO:0016021; GO:0046872; GO:0015031,Golgi membrane; integral to membrane; metal ion binding; protein transport,PF03388;,,,,,,,,,LMAN2_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),protein transport [GO:0015031] comp21685_c0_seq1,280,69.6429,0.94713658,0,26,,2.00E-12,Q54RU1,ABC transporter B family member 6 (ABC transporter ABCB.6),ABC transporter B family member 6 (ABC transporter ABCB.6),GO:0005524; GO:0042626; GO:0070574; GO:0071585; GO:0016021; GO:0005774,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cadmium ion transmembrane transport; detoxification of cadmium ion; integral to membrane; vacuolar membrane",PF00664;PF00005;,,,,,,,,,ABCB6_DICDI,Dictyostelium discoideum (Slime mold),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp21700_c0_seq1,381,43.0446,0.65299595,10,24,,4.00E-07,Q86UF1,Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane),Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604] comp21702_c0_seq1,425,44.9412,0.34442325,7,29,,8.00E-61,Q28CH8,Protein YIPF6 (YIP1 family member 6),Protein YIPF6 (YIP1 family member 6),GO:0016021,integral to membrane,PF04893;,7.00E-58,CHOYP_LOC100743797.1.1,,,,,,,YIPF6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp21712_c0_seq2,1107,43.8121,0.95527201,29,34,,0,Q4KTY1,Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1),Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,4.00E-142,CHOYP_KPSH1.1.1,,,,,,,KPSH1_PINFU,Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata), comp21718_c0_seq1,267,62.5468,1.11469181,0,24,,9.00E-08,Q51548,L-ornithine 5-monooxygenase (EC 1.13.12.-) (L-ornithine N(5)-oxygenase),L-ornithine N(5)-monooxygenase (EC 1.14.13.195) (L-ornithine N(5)-hydroxylase) (Ornithine hydroxylase) (L-ornithine N(5)-oxygenase) (Pyoverdin biosynthesis protein A),GO:0016491; GO:0002049,oxidoreductase activity; pyoverdine biosynthetic process,PF13434;,,,,,,,,,PVDA_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),pyoverdine biosynthetic process [GO:0002049] comp21735_c0_seq1,472,44.9153,0.3167829,16,25,,7.00E-09,Q6ZRR9,Doublecortin domain-containing protein 5,Doublecortin domain-containing protein 5,GO:0035556,intracellular signal transduction,,1.00E-17,CHOYP_LOC100377058.1.1,,,,,,,DCDC5_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp21739_c0_seq1,284,42.6056,0.31147927,3,25,,2.00E-13,Q5F3V0,SET and MYND domain-containing protein 4 (EC 2.1.1.-),SET and MYND domain-containing protein 4 (EC 2.1.1.-),GO:0046872; GO:0008168,metal ion binding; methyltransferase activity,PF00856;PF01753;,,,,,,,,,SMYD4_CHICK,Gallus gallus (Chicken), comp2176_c1_seq1,319,41.0658,0.74627599,6,0,,2.00E-24,Q8N8C0,Zinc finger protein 781,Zinc finger protein 781,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN781_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp21774_c0_seq1,349,39.8281,1.08967271,12,19,,3.00E-10,O08590,Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1),Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1),GO:0007568; GO:0052595; GO:0009308; GO:0052594; GO:0007155; GO:0009986; GO:0005507; GO:0042755; GO:0005615; GO:0016021; GO:0043231; GO:0002523; GO:0052596; GO:0005886; GO:0002675; GO:0010828; GO:0002687; GO:0008131; GO:0042803; GO:0048038; GO:0008217; GO:0052593,aging; aliphatic-amine oxidase activity; amine metabolic process; aminoacetone:oxygen oxidoreductase(deaminating) activity; cell adhesion; cell surface; copper ion binding; eating behavior; extracellular space; integral to membrane; intracellular membrane-bounded organelle; leukocyte migration involved in inflammatory response; phenethylamine:oxygen oxidoreductase (deaminating) activity; plasma membrane; positive regulation of acute inflammatory response; positive regulation of glucose transport; positive regulation of leukocyte migration; primary amine oxidase activity; protein homodimerization activity; quinone binding; regulation of blood pressure; tryptamine:oxygen oxidoreductase (deaminating) activity,PF01179;PF02727;PF02728;,,,,,,,,,AOC3_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]; eating behavior [GO:0042755]; leukocyte migration involved in inflammatory response [GO:0002523]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of glucose transport [GO:0010828]; positive regulation of leukocyte migration [GO:0002687]; regulation of blood pressure [GO:0008217]; response to immobilization stress [GO:0035902] comp21778_c0_seq1,288,39.5833,0.26984452,7,19,,5.00E-21,Q86TV6,Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),,,PF13181;,,,,,,,,,TTC7B_HUMAN,Homo sapiens (Human),establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854] comp21779_c0_seq1,305,47.541,0.85407617,0,33,,6.00E-40,Q55FI1,4-aminobutyrate aminotransferase (EC 2.6.1.19) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase),4-aminobutyrate aminotransferase (EC 2.6.1.19) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase),GO:0003867; GO:0032144; GO:0009448; GO:0005739; GO:0042803; GO:0030170,4-aminobutyrate transaminase activity; 4-aminobutyrate transaminase complex; gamma-aminobutyric acid metabolic process; mitochondrion; protein homodimerization activity; pyridoxal phosphate binding,PF00202;,5.00E-26,CHOYP_GABT.1.2,,,,,,,GABT_DICDI,Dictyostelium discoideum (Slime mold),gamma-aminobutyric acid catabolic process [GO:0009450] comp21814_c0_seq1,229,40.1747,0.32624736,0,18,,3.00E-17,Q5RFI2,Ras-related protein Rab-28,Ras-related protein Rab-28,GO:0019003; GO:0005525; GO:0035253; GO:0036064; GO:0005886; GO:0007264,GDP binding; GTP binding; ciliary rootlet; cilium basal body; plasma membrane; small GTPase mediated signal transduction,PF00071;,9.00E-22,CHOYP_LOC100366300.1.1,,,,,,,RAB28_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),small GTPase mediated signal transduction [GO:0007264] comp21829_c0_seq1,465,44.3011,1.05509922,24,17,,1.00E-35,P09848,Lactase-phlorizin hydrolase (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)],Lactase-phlorizin hydrolase (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)],GO:0016324; GO:0005975; GO:0017042; GO:0005887; GO:0000016; GO:0044245; GO:0044281,apical plasma membrane; carbohydrate metabolic process; glycosylceramidase activity; integral to plasma membrane; lactase activity; polysaccharide digestion; small molecule metabolic process,PF00232;,2.00E-33,CHOYP_LOC100371429.1.1,,,,,,,LPH_HUMAN,Homo sapiens (Human),carbohydrate metabolic process [GO:0005975]; glycosyl compound metabolic process [GO:1901657]; polysaccharide digestion [GO:0044245]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to nickel cation [GO:0010045]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to sucrose [GO:0009744] comp21853_c0_seq1,269,42.7509,0.9016518,0,32,,1.00E-22,P18502,Protein patched (Hedgehog receptor),Protein patched (Hedgehog receptor),GO:0001746; GO:0048099; GO:0007411; GO:0016311; GO:0035225; GO:0009880; GO:0030139; GO:0007455; GO:0042078; GO:0008406; GO:0008158; GO:0007476; GO:0005887; GO:0055088; GO:0030228; GO:0045879; GO:0030707; GO:0048471; GO:0007422; GO:0006508; GO:0007346; GO:0042306; GO:0007367; GO:0007224; GO:0048103; GO:0048100,"Bolwig's organ morphogenesis; anterior/posterior lineage restriction, imaginal disc; axon guidance; dephosphorylation; determination of genital disc primordium; embryonic pattern specification; endocytic vesicle; eye-antennal disc morphogenesis; germ-line stem cell division; gonad development; hedgehog receptor activity; imaginal disc-derived wing morphogenesis; integral to plasma membrane; lipid homeostasis; lipoprotein particle receptor activity; negative regulation of smoothened signaling pathway; ovarian follicle cell development; perinuclear region of cytoplasm; peripheral nervous system development; proteolysis; regulation of mitotic cell cycle; regulation of protein import into nucleus; segment polarity determination; smoothened signaling pathway; somatic stem cell division; wing disc anterior/posterior pattern formation",PF02460;,,,,,,,,,PTC_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior lineage restriction, imaginal disc [GO:0048099]; anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; blastoderm segmentation [GO:0007350]; Bolwig's organ morphogenesis [GO:0001746]; dephosphorylation [GO:0016311]; determination of genital disc primordium [GO:0035225]; embryonic pattern specification [GO:0009880]; eye-antennal disc morphogenesis [GO:0007455]; germ-line stem cell division [GO:0042078]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; lipid homeostasis [GO:0055088]; negative regulation of smoothened signaling pathway [GO:0045879]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein import into nucleus [GO:0042306]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; somatic stem cell division [GO:0048103]; wing disc anterior/posterior pattern formation [GO:0048100]" comp21854_c0_seq1,341,43.1085,0.57425867,21,14,,2.00E-13,Q6XDT6,Ikaros family zinc finger protein (Ikaros-like transcription factor) (HIL),Ikaros family zinc finger protein (Ikaros-like transcription factor) (HIL),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,1.00E-29,CHOYP_IKZF.1.1,,,,,,,IKZF_MYXGL,Myxine glutinosa (Atlantic hagfish),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp21886_c0_seq1,452,40.708,0.42862422,7,26,,1.00E-47,Q9NPA5,"Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)","Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)",GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZF64A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp21903_c0_seq1,219,41.0959,0.43651704,6,10,,3.00E-14,B6MUN4,"Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)","Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)",GO:0003677; GO:0003682; GO:0006338; GO:0042393; GO:0046872; GO:0008237; GO:0035522; GO:0005634; GO:0045944; GO:0006508; GO:0003713; GO:0006351; GO:0004221; GO:0004843,"DNA binding; chromatin binding; chromatin remodeling; histone binding; metal ion binding; metallopeptidase activity; monoubiquitinated histone H2A deubiquitination; nucleus; positive regulation of transcription from RNA polymerase II promoter; proteolysis; transcription coactivator activity; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-specific protease activity",PF01398;PF04433;,,,,,,,,,MYSM1_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),"chromatin remodeling [GO:0006338]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp21916_c0_seq1,285,44.5614,0.36667118,8,10,,3.00E-36,O46160,60S ribosomal protein L14,60S ribosomal protein L14,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01929;,7.00E-81,CHOYP_RL14.7.9,5.00E-24,ruditapes_lrc34472,,,,,RL14_LUMRU,Lumbricus rubellus (Humus earthworm),translation [GO:0006412] comp21921_c0_seq1,215,42.3256,0.62975123,2,25,,2.00E-11,Q92618,Zinc finger protein 516,Zinc finger protein 516,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN516_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cold [GO:0009409]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]" comp21929_c0_seq1,337,50.7418,1.22430724,6,40,,5.00E-11,Q71MB6,Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),GO:0016323; GO:0030154; GO:0016021; GO:0006811; GO:0007275; GO:0007283; GO:0005215,basolateral plasma membrane; cell differentiation; integral to membrane; ion transport; multicellular organismal development; spermatogenesis; transporter activity,PF07648;PF03137;,,,,,,,,,SO4C1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; sodium-independent organic anion transport [GO:0043252]; spermatogenesis [GO:0007283]; transport [GO:0006810] comp21931_c0_seq1,298,42.953,0.58399095,9,23,,1.00E-44,Q8INB9,RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB),RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB),GO:0005524; GO:0006915; GO:0009986; GO:0008362; GO:0007623; GO:0005829; GO:0031104; GO:0007427; GO:0008286; GO:0035556; GO:0019915; GO:0060292; GO:0043066; GO:0045886; GO:0035091; GO:0005886; GO:0048680; GO:0030307; GO:0045793; GO:0040018; GO:0046622; GO:0004674; GO:0008360; GO:0050773; GO:0035206; GO:0042306; GO:0006979,"ATP binding; apoptotic process; cell surface; chitin-based embryonic cuticle biosynthetic process; circadian rhythm; cytosol; dendrite regeneration; epithelial cell migration, open tracheal system; insulin receptor signaling pathway; intracellular signal transduction; lipid storage; long term synaptic depression; negative regulation of apoptotic process; negative regulation of synaptic growth at neuromuscular junction; phosphatidylinositol binding; plasma membrane; positive regulation of axon regeneration; positive regulation of cell growth; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; protein serine/threonine kinase activity; regulation of cell shape; regulation of dendrite development; regulation of hemocyte proliferation; regulation of protein import into nucleus; response to oxidative stress",PF00169;PF00069;PF00433;,3.00E-48,CHOYP_AKT1.1.2,,,,,,,AKT1_DROME,Drosophila melanogaster (Fruit fly),"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]" comp21942_c0_seq1,365,47.1233,0.56386978,10,26,,6.00E-16,Q9JIR0,Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (RIMS-binding protein 1) (RIM-BP1),Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1),GO:0005739,mitochondrion,PF07653;PF14604;,3.00E-24,CHOYP_RIMB1.5.5,,,,,,,RIMB1_RAT,Rattus norvegicus (Rat), comp21948_c0_seq1,331,48.9426,1.21111335,6,19,,2.00E-11,P41740,Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C),Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C),GO:0008528; GO:0007193; GO:0005887; GO:0016941; GO:0007194; GO:0048662; GO:0002158; GO:0030157; GO:0017046; GO:0048015; GO:0007200; GO:0051000; GO:0035810; GO:0042803; GO:0008217; GO:0033688; GO:0001501,G-protein coupled peptide receptor activity; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; integral to plasma membrane; natriuretic peptide receptor activity; negative regulation of adenylate cyclase activity; negative regulation of smooth muscle cell proliferation; osteoclast proliferation; pancreatic juice secretion; peptide hormone binding; phosphatidylinositol-mediated signaling; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of nitric-oxide synthase activity; positive regulation of urine volume; protein homodimerization activity; regulation of blood pressure; regulation of osteoblast proliferation; skeletal system development,PF01094;,,,,,,,,,ANPRC_RAT,Rattus norvegicus (Rat),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP-mediated signaling [GO:0019933]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of smooth muscle cell proliferation [GO:0048662]; osteoclast proliferation [GO:0002158]; pancreatic juice secretion [GO:0030157]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of urine volume [GO:0035810]; regulation of blood pressure [GO:0008217]; regulation of osteoblast proliferation [GO:0033688]; skeletal system development [GO:0001501] comp21966_c0_seq1,313,44.7284,0.60853334,11,24,,5.00E-13,O15040,Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297),Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297),GO:0006914; GO:0008219,autophagy; cell death,PF06462;,3.00E-23,CHOYP_BRAFLDRAFT_216841.4.4,,,,,,,TCPR2_HUMAN,Homo sapiens (Human),autophagy [GO:0006914] comp21973_c0_seq1,243,51.8519,0.49293764,8,29,,4.00E-10,Q5EAU3,"Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 2 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase II) (Transmembrane protein 55A)","Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 2 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase II) (Transmembrane protein 55A)",GO:0016787; GO:0016021; GO:0031902; GO:0005765,hydrolase activity; integral to membrane; late endosome membrane; lysosomal membrane,PF09788;,1.00E-14,CHOYP_LOC100368816.2.2,,,,,,,TM55A_XENLA,Xenopus laevis (African clawed frog),phosphatidylinositol dephosphorylation [GO:0046856] comp21983_c0_seq1,203,67.9803,1.11995961,0,21,,4.00E-22,P25856,"Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic (EC 1.2.1.13) (NADP-dependent glyceraldehydephosphate dehydrogenase A subunit 1)","Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic (EC 1.2.1.13) (NADP-dependent glyceraldehydephosphate dehydrogenase A subunit 1)",GO:0051287; GO:0050661; GO:0048046; GO:0009941; GO:0031969; GO:0009570; GO:0009535; GO:0006006; GO:0047100; GO:0019253; GO:0009409; GO:0009416; GO:0009744; GO:0010319,NAD binding; NADP binding; apoplast; chloroplast envelope; chloroplast membrane; chloroplast stroma; chloroplast thylakoid membrane; glucose metabolic process; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity; reductive pentose-phosphate cycle; response to cold; response to light stimulus; response to sucrose stimulus; stromule,PF02800;PF00044;,,,,,,,,,G3PA_ARATH,Arabidopsis thaliana (Mouse-ear cress),glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]; response to cold [GO:0009409]; response to light stimulus [GO:0009416]; response to sucrose [GO:0009744] comp21998_c0_seq1,354,43.2203,0.42683267,3,29,,8.00E-23,Q9BZC7,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0043190; GO:0042626; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0006629; GO:0005765; GO:0005764; GO:0005815; GO:0032383; GO:0006357; GO:0042493; GO:0048545,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lipid metabolic process; lysosomal membrane; lysosome; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus",PF00005;,,,,,,,,,ABCA2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp22000_c0_seq1,285,50.5263,0.50630049,12,6,,,,,,,,,8.00E-11,CHOYP_MD12L.1.1,,,,,,,,, comp22000_c0_seq2,222,52.2523,0.53175446,0,0,,3.00E-15,Q8BQM9,Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF09497;PF12145;PF12144;,,,,,,,,,MD12L_MOUSE,Mus musculus (Mouse), comp22001_c0_seq1,233,42.4893,0.67408649,1,23,,5.00E-19,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,2.00E-11,CHOYP_LOC100533356.1.6,,,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp22006_c0_seq1,550,38.3636,0.55503846,8,26,,5.00E-08,Q9NY99,Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5),Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5),GO:0007417; GO:0005737; GO:0005856; GO:0005543; GO:0042383; GO:0016013,central nervous system development; cytoplasm; cytoskeleton; phospholipid binding; sarcolemma; syntrophin complex,PF00595;,,,,,,,,,SNTG2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417] comp22023_c0_seq1,253,43.4783,0.75571429,3,25,,4.00E-09,Q80SY4,E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1),E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1),GO:0007219; GO:0001568; GO:0005813; GO:0031410; GO:0001947; GO:0001701; GO:0045665; GO:0001841; GO:0031965; GO:0005886; GO:0045807; GO:0001756; GO:0004842; GO:0008270,Notch signaling pathway; blood vessel development; centrosome; cytoplasmic vesicle; heart looping; in utero embryonic development; negative regulation of neuron differentiation; neural tube formation; nuclear membrane; plasma membrane; positive regulation of endocytosis; somitogenesis; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB1_MOUSE,Mus musculus (Mouse),blood vessel development [GO:0001568]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756] comp22037_c0_seq1,222,45.4955,0.43726377,4,18,,2.00E-25,Q9Z1C7,Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Fragment),Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Fragment),GO:0017016; GO:0005088; GO:0016324; GO:0030424; GO:0016323; GO:0030552; GO:0005737; GO:0043197; GO:0060076; GO:0006887; GO:0007507; GO:0050805; GO:0001917; GO:0001750; GO:0014911; GO:0043234; GO:0032403; GO:0050773; GO:0051056; GO:0007165; GO:0007264,Ras GTPase binding; Ras guanyl-nucleotide exchange factor activity; apical plasma membrane; axon; basolateral plasma membrane; cAMP binding; cytoplasm; dendritic spine; excitatory synapse; exocytosis; heart development; negative regulation of synaptic transmission; photoreceptor inner segment; photoreceptor outer segment; positive regulation of smooth muscle cell migration; protein complex; protein complex binding; regulation of dendrite development; regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction,PF00617;,,,,,,,,,RPGF4_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; cAMP-mediated signaling [GO:0019933]; cellular response to nerve growth factor stimulus [GO:1990090]; exocytosis [GO:0006887]; ganglion development [GO:0061548]; heart development [GO:0007507]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; response to benzene [GO:1901423]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; spinal cord development [GO:0021510] comp22046_c0_seq1,390,45.641,0.25615997,5,21,,2.00E-24,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-43,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp22061_c0_seq1,451,48.7805,0.86289907,0,46,,1.00E-45,P32242,Homeobox protein OTX1 (Orthodenticle homolog 1),Homeobox protein OTX1 (Orthodenticle homolog 1),GO:0009952; GO:0048852; GO:0042472; GO:0022037; GO:0030901; GO:0007275; GO:0005634; GO:0006357; GO:0043565; GO:0003700,anterior/posterior pattern specification; diencephalon morphogenesis; inner ear morphogenesis; metencephalon development; midbrain development; multicellular organismal development; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;PF03529;,4.00E-61,CHOYP_OTX5B.1.1,,,,,,,OTX1_HUMAN,Homo sapiens (Human),anterior/posterior pattern specification [GO:0009952]; diencephalon morphogenesis [GO:0048852]; inner ear morphogenesis [GO:0042472]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp22069_c0_seq1,802,45.5112,0.60285379,7,52,,7.00E-49,Q8WPJ2,"Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)","Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)",GO:0046355; GO:0016985,"mannan catabolic process; mannan endo-1,4-beta-mannosidase activity",PF00150;,,,,,,,,,MANA_MYTED,Mytilus edulis (Blue mussel),mannan catabolic process [GO:0046355] comp22081_c0_seq1,559,34.1682,0.31152748,4,63,,3.00E-11,O70237,Zinc finger protein Gfi-1b (Growth factor independent protein 1B),Zinc finger protein Gfi-1b (Growth factor independent protein 1B),GO:0003677; GO:0046872; GO:0007275; GO:0051572; GO:0005634; GO:0030854; GO:0051574; GO:0045646; GO:0006355; GO:0006351,"DNA binding; metal ion binding; multicellular organismal development; negative regulation of histone H3-K4 methylation; nucleus; positive regulation of granulocyte differentiation; positive regulation of histone H3-K9 methylation; regulation of erythrocyte differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,GFI1B_MOUSE,Mus musculus (Mouse),"hemopoiesis [GO:0030097]; negative regulation of histone H3-K4 methylation [GO:0051572]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K9 methylation [GO:0051574]; regulation of erythrocyte differentiation [GO:0045646]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp22082_c0_seq1,925,43.4595,0.5771347,8,7,,1.00E-28,Q5W4S4,Folliculin-interacting protein 1,Folliculin-interacting protein 1,GO:0031929; GO:0009267; GO:0005737; GO:0005085; GO:0002327; GO:0032007; GO:0043154; GO:0000122; GO:0002904; GO:0033138; GO:2000973,TOR signaling cascade; cellular response to starvation; cytoplasm; guanyl-nucleotide exchange factor activity; immature B cell differentiation; negative regulation of TOR signaling cascade; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of B cell apoptotic process; positive regulation of peptidyl-serine phosphorylation; regulation of pro-B cell differentiation,PF14638;PF14637;PF14636;,,,,,,,,,FNIP1_CHICK,Gallus gallus (Chicken),cellular response to starvation [GO:0009267]; immature B cell differentiation [GO:0002327]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; regulation of pro-B cell differentiation [GO:2000973]; TOR signaling [GO:0031929] comp22102_c0_seq1,565,43.0088,0.4607259,23,16,,6.00E-32,A7YWD2,Importin-13 (Imp13),Importin-13 (Imp13),GO:0005737; GO:0005634; GO:0006606,cytoplasm; nucleus; protein import into nucleus,PF03810;PF08389;,,,,,,,,,IPO13_BOVIN,Bos taurus (Bovine),protein import into nucleus [GO:0006606] comp22103_c0_seq1,204,36.7647,0.73531179,0,8,,2.00E-08,Q8TF20,Zinc finger protein 721,Zinc finger protein 721,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN721_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp22116_c0_seq1,558,44.4444,0.44462263,12,23,,3.00E-29,P83038,Histone deacetylase 4 (HD4) (EC 3.5.1.98),Histone deacetylase 4 (HD4) (EC 3.5.1.98),GO:0030183; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0006954; GO:0046872; GO:0045843; GO:0045892; GO:0007399; GO:0008134; GO:0006351,"B cell differentiation; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; inflammatory response; metal ion binding; negative regulation of striated muscle tissue development; negative regulation of transcription, DNA-dependent; nervous system development; transcription factor binding; transcription, DNA-dependent",PF12203;PF00850;,4.00E-31,CHOYP_ISCW_ISCW014481.1.1,,,,,,,HDAC4_CHICK,Gallus gallus (Chicken),"B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; inflammatory response [GO:0006954]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]" comp22121_c0_seq1,396,43.6869,0.48115039,2,46,,1.00E-10,Q6GM16,Nucleoredoxin (EC 1.8.1.8),Nucleoredoxin (EC 1.8.1.8),GO:0016055; GO:0072358; GO:0030154; GO:0005829; GO:0030178; GO:0031397; GO:0005634; GO:0047134,Wnt receptor signaling pathway; cardiovascular system development; cell differentiation; cytosol; negative regulation of Wnt receptor signaling pathway; negative regulation of protein ubiquitination; nucleus; protein-disulfide reductase activity,PF13905;,,,,,,,,,NXN_XENLA,Xenopus laevis (African clawed frog),cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp22128_c0_seq1,361,39.8892,0.99314891,25,11,,2.00E-25,Q01664,Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41),Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41),GO:0006978; GO:0070888; GO:0003705; GO:0071549; GO:0043922; GO:0043392; GO:0043066; GO:0071157; GO:0008285; GO:0045736; GO:0045892; GO:0043923; GO:0043065; GO:0045893; GO:0006461; GO:0043565; GO:0017053,"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; E-box binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; cellular response to dexamethasone stimulus; negative regulation by host of viral transcription; negative regulation of DNA binding; negative regulation of apoptotic process; negative regulation of cell cycle arrest; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of transcription, DNA-dependent; positive regulation by host of viral transcription; positive regulation of apoptotic process; positive regulation of transcription, DNA-dependent; protein complex assembly; sequence-specific DNA binding; transcriptional repressor complex",PF00010;,4.00E-29,CHOYP_CEG1A.2.6,,,,,,,TFAP4_HUMAN,Homo sapiens (Human),"cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex assembly [GO:0006461]" comp22146_c0_seq1,494,37.8543,0.51742372,11,18,,4.00E-07,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,,,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp22161_c0_seq1,320,41.875,0.65288773,4,30,,5.00E-08,Q9NYQ8,Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),GO:0005509; GO:0005913; GO:0010631; GO:0007156; GO:0016021; GO:0005634; GO:0005886,calcium ion binding; cell-cell adherens junction; epithelial cell migration; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT2_HUMAN,Homo sapiens (Human),epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp22174_c0_seq1,912,45.8333,0.342453,33,49,,4.00E-106,Q28056,Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase),Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase),GO:0097202; GO:0032237; GO:0070588; GO:0071277; GO:0032541; GO:0060325; GO:0030176; GO:0035108; GO:0008285; GO:0060021; GO:0007389; GO:0004597; GO:0042264; GO:0005886; GO:0010524; GO:0090316; GO:0045862; GO:0045893; GO:0031585; GO:1901879; GO:0031647; GO:0033198,"activation of cysteine-type endopeptidase activity; activation of store-operated calcium channel activity; calcium ion transmembrane transport; cellular response to calcium ion; cortical endoplasmic reticulum; face morphogenesis; integral to endoplasmic reticulum membrane; limb morphogenesis; negative regulation of cell proliferation; palate development; pattern specification process; peptide-aspartate beta-dioxygenase activity; peptidyl-aspartic acid hydroxylation; plasma membrane; positive regulation of calcium ion transport into cytosol; positive regulation of intracellular protein transport; positive regulation of proteolysis; positive regulation of transcription, DNA-dependent; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; regulation of protein depolymerization; regulation of protein stability; response to ATP",PF05279;PF05118;,8.00E-36,CHOYP_ASPH.2.2,,,,,,,ASPH_BOVIN,Bos taurus (Bovine),"activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion transmembrane transport [GO:0070588]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell proliferation [GO:0008285]; palate development [GO:0060021]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]" comp22178_c0_seq1,380,46.3158,0.44302632,8,38,,9.00E-18,Q4V8R6,Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F),GO:0003677; GO:0051301; GO:0005737; GO:0016874; GO:0046872; GO:0007067; GO:0005654; GO:0016567; GO:0040008; GO:0006355; GO:0006351,"DNA binding; cell division; cytoplasm; ligase activity; metal ion binding; mitosis; nucleoplasm; protein ubiquitination; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,2.00E-20,CHOYP_LOC100694005.1.1,,,,,,,E4F1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]" comp22183_c0_seq1,747,43.5074,0.31183259,23,19,,3.00E-23,Q8K448,ATP-binding cassette sub-family A member 5,ATP-binding cassette sub-family A member 5,GO:0005524; GO:0006200; GO:0016887; GO:0000139; GO:0033344; GO:0034375; GO:0016021; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0010745; GO:0043691,ATP binding; ATP catabolic process; ATPase activity; Golgi membrane; cholesterol efflux; high-density lipoprotein particle remodeling; integral to membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; negative regulation of macrophage derived foam cell differentiation; reverse cholesterol transport,PF00005;,,,,,,,,,ABCA5_MOUSE,Mus musculus (Mouse),cholesterol efflux [GO:0033344]; high-density lipoprotein particle remodeling [GO:0034375]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; reverse cholesterol transport [GO:0043691] comp22184_c0_seq1,229,40.6114,0.42554003,11,19,,3.00E-07,O60294,Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein) (tRNA wybutosine-synthesizing protein 4 homolog) (tRNA yW-synthesizing protein 4 homolog),tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase),GO:0008168; GO:0008033,methyltransferase activity; tRNA processing,PF04072;,,,,,,,,,LCMT2_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488]; tRNA modification [GO:0006400]; wybutosine biosynthetic process [GO:0031591] comp22195_c0_seq1,341,46.3343,0.44093852,8,34,,9.00E-15,P97739,Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),GO:0016021; GO:0046872; GO:0004222; GO:0005886; GO:0006508,integral to membrane; metal ion binding; metalloendopeptidase activity; plasma membrane; proteolysis,PF01431;PF05649;,4.00E-34,CHOYP_LOC100118995.1.1,,,,,,,ECE1_CAVPO,Cavia porcellus (Guinea pig),protein processing [GO:0016485] comp22209_c0_seq1,221,41.1765,0.44092263,3,21,,4.00E-33,Q9ERS4,Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1),Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1),GO:0005545; GO:0005794; GO:0016020,1-phosphatidylinositol binding; Golgi apparatus; membrane,PF00169;,7.00E-23,CHOYP_LOC100370358.1.1,,,,,,,PKHA3_MOUSE,Mus musculus (Mouse), comp22219_c0_seq1,486,44.6502,0.95900871,18,11,,1.00E-07,F7J220,Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),GO:0030659; GO:0045087; GO:0016021; GO:0006909; GO:0005044,cytoplasmic vesicle membrane; innate immune response; integral to membrane; phagocytosis; scavenger receptor activity,PF00530;PF00084;,,,,,,,,,SRCR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),innate immune response [GO:0045087]; phagocytosis [GO:0006909] comp22236_c0_seq1,328,48.4756,0.91121733,0,15,,2.00E-64,P05419,Neo-calmodulin (NeoCaM) (Fragment),Neo-calmodulin (NeoCaM) (Fragment),GO:0005509,calcium ion binding,PF13499;,1.00E-22,CHOYP_CALM.23.50,5.00E-56,ruditapes_s39672,,,,,CALN_CHICK,Gallus gallus (Chicken), comp22236_c0_seq2,387,45.478,0.9189535,0,2,,9.00E-69,P62155,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,1.00E-66,CHOYP_LOC100533341.1.1,3.00E-67,ruditapes_lrc35916,,,,,CALM_XENLA,Xenopus laevis (African clawed frog), comp22252_c0_seq1,212,61.3208,1.00854517,0,28,,6.00E-07,Q46170,Arginine/ornithine antiporter,Arginine/ornithine antiporter,GO:0006527; GO:0043858; GO:0005887,arginine catabolic process; arginine:ornithine antiporter activity; integral to plasma membrane,PF13520;,,,,,,,,,ARCD_CLOPE,Clostridium perfringens (strain 13 / Type A),arginine catabolic process [GO:0006527] comp22266_c0_seq1,613,45.0245,0.51759885,22,39,,3.00E-22,Q9VY77,LIM domain-containing protein jub,LIM domain-containing protein jub,GO:0003779; GO:0005912; GO:0035329; GO:0007067; GO:0045572; GO:0071539; GO:0008270,actin binding; adherens junction; hippo signaling cascade; mitosis; positive regulation of imaginal disc growth; protein localization to centrosome; zinc ion binding,PF00412;,1.00E-32,CHOYP_LOC408431.1.1,,,,,,,AJUBA_DROME,Drosophila melanogaster (Fruit fly),hippo signaling [GO:0035329]; mitotic nuclear division [GO:0007067]; ovarian follicle cell development [GO:0030707]; positive regulation of imaginal disc growth [GO:0045572]; positive regulation of organ growth [GO:0046622]; protein localization to centrosome [GO:0071539] comp22272_c0_seq1,337,43.3234,0.76169685,2,24,,9.00E-25,Q3AAW2,Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (HTA) (Homoserine transacetylase),Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (HTA) (Homoserine transacetylase),GO:0005737; GO:0004414; GO:0009086,cytoplasm; homoserine O-acetyltransferase activity; methionine biosynthetic process,PF00561;,1.00E-10,CHOYP_LOC100374280.1.1,,,,,,,METX_CARHZ,Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901),methionine biosynthetic process [GO:0009086] comp22272_c1_seq1,450,47.3333,0.96367997,0,45,,2.00E-39,Q10341,Probable serine-O-acetyltransferase cys2 (EC 2.3.1.-),Probable serine-O-acetyltransferase (EC 2.3.1.30),GO:0019344; GO:0004414; GO:0009086; GO:0005739,cysteine biosynthetic process; homoserine O-acetyltransferase activity; methionine biosynthetic process; mitochondrion,PF00561;,,,,,,,,,CYS2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),cysteine biosynthetic process [GO:0019344]; methionine biosynthetic process [GO:0009086] comp22276_c0_seq1,516,38.9535,0.48732902,12,31,,2.00E-92,Q8INB9,RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB),RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB),GO:0005524; GO:0006915; GO:0009986; GO:0008362; GO:0007623; GO:0005829; GO:0031104; GO:0007427; GO:0008286; GO:0035556; GO:0019915; GO:0060292; GO:0043066; GO:0045886; GO:0035091; GO:0005886; GO:0048680; GO:0030307; GO:0045793; GO:0040018; GO:0046622; GO:0004674; GO:0008360; GO:0050773; GO:0035206; GO:0042306; GO:0006979,"ATP binding; apoptotic process; cell surface; chitin-based embryonic cuticle biosynthetic process; circadian rhythm; cytosol; dendrite regeneration; epithelial cell migration, open tracheal system; insulin receptor signaling pathway; intracellular signal transduction; lipid storage; long term synaptic depression; negative regulation of apoptotic process; negative regulation of synaptic growth at neuromuscular junction; phosphatidylinositol binding; plasma membrane; positive regulation of axon regeneration; positive regulation of cell growth; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; protein serine/threonine kinase activity; regulation of cell shape; regulation of dendrite development; regulation of hemocyte proliferation; regulation of protein import into nucleus; response to oxidative stress",PF00169;PF00069;PF00433;,4.00E-138,CHOYP_AKT1.2.2,,,,,,,AKT1_DROME,Drosophila melanogaster (Fruit fly),"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]" comp2228_c0_seq1,201,42.2886,0.68244932,4,2,,6.00E-13,P28039,Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit],Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit],GO:0050528; GO:0005576; GO:0006954; GO:0006629; GO:0008653; GO:0004465; GO:0050728,acyloxyacyl hydrolase activity; extracellular region; inflammatory response; lipid metabolic process; lipopolysaccharide metabolic process; lipoprotein lipase activity; negative regulation of inflammatory response,PF00657;PF03489;,,,,,,,,,AOAH_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629] comp22295_c0_seq1,701,39.8003,0.505037,8,73,,1.00E-08,Q4KMC9,Uncharacterized protein C1orf198 homolog,Uncharacterized protein C1orf198 homolog,,,PF15797;,3.00E-21,CHOYP_CA198.1.1,,,,,,,CA198_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp22301_c0_seq1,275,48.7273,0.37424224,5,38,,3.00E-20,O95905,Protein SGT1 (hSGT1) (Protein ecdysoneless homolog) (Suppressor of GCR2),Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1),GO:0008283; GO:0005737; GO:0005634; GO:2000045; GO:0006110; GO:0006355; GO:0003713; GO:0006366,"cell proliferation; cytoplasm; nucleus; regulation of G1/S transition of mitotic cell cycle; regulation of glycolysis; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter",PF07093;,,,,,,,,,SGT1_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of glycolytic process [GO:0006110]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp22302_c0_seq1,216,50.9259,1.07605612,3,26,,2.00E-06,P05616,Ovomucoid (Fragment),Ovomucoid (Fragment),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,IOVO_CARRE,Carpococcyx renauldi (Coral-billed ground-cuckoo), comp22307_c0_seq1,303,44.8845,0.26579524,3,30,,5.00E-14,Q1L9A2,Optic atrophy 3 protein homolog,Optic atrophy 3 protein homolog,GO:0007626; GO:0005739; GO:0050881; GO:0031413,locomotory behavior; mitochondrion; musculoskeletal movement; regulation of buoyancy,PF07047;,,,,,,,,,OPA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),locomotory behavior [GO:0007626]; musculoskeletal movement [GO:0050881]; regulation of buoyancy [GO:0031413]; regulation of lipid metabolic process [GO:0019216] comp22326_c0_seq1,811,42.7867,0.2815343,23,45,,2.00E-19,P98063,Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP),Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP),GO:0005794; GO:0005509; GO:0051216; GO:0030154; GO:0005615; GO:0004222; GO:0001503; GO:0061036; GO:0005578; GO:0006508; GO:0008270,Golgi apparatus; calcium ion binding; cartilage development; cell differentiation; extracellular space; metalloendopeptidase activity; ossification; positive regulation of cartilage development; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF01400;PF00431;PF07645;,,,,,,,,,BMP1_MOUSE,Mus musculus (Mouse),BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell development [GO:0048468]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395] comp22328_c0_seq1,892,36.0987,0.31277281,28,54,,4.00E-09,Q7ZVR6,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,7.00E-18,CHOYP_BRAFLDRAFT_71707.1.1,,,,,,,MYNN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp22330_c0_seq1,434,40.553,0.63902583,8,26,,8.00E-35,Q6DDJ3,Differentially expressed in FDCP 8 homolog A (DEF-8-A),Differentially expressed in FDCP 8 homolog A (DEF-8-A),GO:0035556; GO:0008270,intracellular signal transduction; zinc ion binding,PF00130;PF13901;,8.00E-32,CHOYP_DFI8A.1.1,,,,,,,DFI8A_XENLA,Xenopus laevis (African clawed frog),intracellular signal transduction [GO:0035556] comp22335_c0_seq1,506,43.8735,0.82405848,4,47,,8.00E-40,Q27312,ADP-ribosyl cyclase (ADRC) (EC 3.2.2.5) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase),ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase) (ADPRC) (ADRC) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase),GO:0003953; GO:0016023; GO:0007338,NAD+ nucleosidase activity; cytoplasmic membrane-bounded vesicle; single fertilization,PF02267;,,,,,,,,,NADA_APLKU,Aplysia kurodai (Kuroda's sea hare),single fertilization [GO:0007338] comp22340_c0_seq1,472,39.4068,1.17509104,10,42,,1.00E-06,Q6NW40,RGM domain family member B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON),RGM domain family member B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON),GO:0030509; GO:0046658; GO:0007411; GO:0007155; GO:0005793; GO:0042802; GO:0045121; GO:0045893,"BMP signaling pathway; anchored to plasma membrane; axon guidance; cell adhesion; endoplasmic reticulum-Golgi intermediate compartment; identical protein binding; membrane raft; positive regulation of transcription, DNA-dependent",PF06534;PF06535;,,,,,,,,,RGMB_HUMAN,Homo sapiens (Human),"BMP signaling pathway [GO:0030509]; cell adhesion [GO:0007155]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]" comp22343_c0_seq1,297,45.7912,0.90094045,10,21,,2.00E-09,A0JM12,Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10),Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10),GO:0007155; GO:0016021; GO:0006909; GO:0005886; GO:0014719; GO:0014816; GO:0014841,cell adhesion; integral to membrane; phagocytosis; plasma membrane; satellite cell activation; satellite cell differentiation; satellite cell proliferation,PF12661;PF00053;,,,,,,,,,MEG10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell proliferation [GO:0014841] comp22361_c0_seq1,582,44.5017,0.73584783,2,64,,,,,,,,,1.00E-30,CHOYP_LOC657327.1.1,,,,,,,,, comp22366_c0_seq1,238,49.5798,0.82987576,0,26,,1.00E-06,P63047,Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST),GO:0005737; GO:0008202; GO:0008146; GO:0006790,cytoplasm; steroid metabolic process; sulfotransferase activity; sulfur compound metabolic process,PF00685;,,,,,,,,,ST4A1_RAT,Rattus norvegicus (Rat),steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790] comp22389_c0_seq1,599,41.5693,0.78339427,6,70,,4.00E-07,P07207,Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],GO:0005796; GO:0061382; GO:0007219; GO:0048052; GO:0007464; GO:0045466; GO:0045463; GO:0007460; GO:0007015; GO:0005912; GO:0008356; GO:0007298; GO:0005509; GO:0009986; GO:0008407; GO:0003682; GO:0042676; GO:0046667; GO:0005829; GO:0008340; GO:0046843; GO:0007391; GO:0007451; GO:0007398; GO:0035165; GO:0005788; GO:0005768; GO:0061331; GO:0035153; GO:0035214; GO:0007440; GO:0060288; GO:0030718; GO:0030708; GO:0007403; GO:0008347; GO:0035172; GO:0007157; GO:0007446; GO:0016348; GO:0048803; GO:0008587; GO:0007474; GO:0016021; GO:0035171; GO:0046331; GO:0007616; GO:0035170; GO:0007498; GO:0008045; GO:0007521; GO:0046329; GO:0045316; GO:0035157; GO:0050768; GO:0035155; GO:0000122; GO:0007400; GO:0005654; GO:0007314; GO:0030720; GO:0030713; GO:0007422; GO:1900087; GO:0045747; GO:0008284; GO:0045944; GO:0043234; GO:0045468; GO:0042686; GO:0042689; GO:0051489; GO:0040008; GO:0009608; GO:0016330; GO:0007519; GO:0035003; GO:0006351; GO:0004888; GO:0007419; GO:0048190; GO:0007473,"Golgi lumen; Malpighian tubule tip cell differentiation; Notch signaling pathway; R1/R6 cell differentiation; R3/R4 cell fate commitment; R7 cell differentiation; R8 cell development; R8 cell fate commitment; actin filament organization; adherens junction; asymmetric cell division; border follicle cell migration; calcium ion binding; cell surface; chaeta morphogenesis; chromatin binding; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; cytosol; determination of adult lifespan; dorsal appendage formation; dorsal closure; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; embryonic crystal cell differentiation; endoplasmic reticulum lumen; endosome; epithelial cell proliferation involved in Malpighian tubule morphogenesis; epithelial cell type specification, open tracheal system; eye-antennal disc development; foregut morphogenesis; formation of a compartment boundary; germ-line stem cell maintenance; germarium-derived female germ-line cyst encapsulation; glial cell fate determination; glial cell migration; hemocyte proliferation; heterophilic cell-cell adhesion; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived male genitalia morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; lamellocyte differentiation; lateral inhibition; long-term memory; lymph gland crystal cell differentiation; mesoderm development; motor neuron axon guidance; muscle cell fate determination; negative regulation of JNK cascade; negative regulation of compound eye photoreceptor development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleoplasm; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of Notch signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of R8 cell spacing in compound eye; regulation of cardioblast cell fate specification; regulation of crystal cell differentiation; regulation of filopodium assembly; regulation of growth; response to symbiont; second mitotic wave involved in compound eye morphogenesis; skeletal muscle tissue development; subapical complex; transcription, DNA-dependent; transmembrane signaling receptor activity; ventral cord development; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTCH_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]" comp22403_c0_seq1,916,40.8297,0.34188001,31,36,,2.00E-26,A0JPE1,Protein FAM69B,Protein FAM69B,GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF12260;PF14875;,,,,,,,,,FA69B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp22409_c0_seq1,275,41.0909,0.35048082,3,26,,1.00E-12,Q01968,Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein),Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein),GO:0005795; GO:0005798; GO:0030675; GO:0042384; GO:0030136; GO:0005905; GO:0005829; GO:0005769; GO:0031901; GO:0001701; GO:0043647; GO:0052745; GO:0005634; GO:0030670; GO:0006661; GO:0046856; GO:0004439; GO:0001750; GO:0005886; GO:0032314; GO:0007264; GO:0005802,"Golgi stack; Golgi-associated vesicle; Rac GTPase activator activity; cilium assembly; clathrin-coated vesicle; coated pit; cytosol; early endosome; early endosome membrane; in utero embryonic development; inositol phosphate metabolic process; inositol phosphate phosphatase activity; nucleus; phagocytic vesicle membrane; phosphatidylinositol biosynthetic process; phosphatidylinositol dephosphorylation; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; photoreceptor outer segment; plasma membrane; regulation of Rac GTPase activity; small GTPase mediated signal transduction; trans-Golgi network",PF03372;PF16726;PF00620;,,,,,,,,,OCRL_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp22410_c0_seq1,352,44.0341,0.78124567,20,22,,6.00E-19,Q99NH7,Prestin (Solute carrier family 26 member 5),Prestin (Solute carrier family 26 member 5),GO:0016323; GO:0016021; GO:0016328; GO:0008360; GO:0042391; GO:0008271; GO:0007605; GO:0030507; GO:0008272,basolateral plasma membrane; integral to membrane; lateral plasma membrane; regulation of cell shape; regulation of membrane potential; secondary active sulfate transmembrane transporter activity; sensory perception of sound; spectrin binding; sulfate transport,PF01740;PF00916;,6.00E-33,CHOYP_LOC100552593.1.3,,,,,,,S26A5_MOUSE,Mus musculus (Mouse),bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; fructose transport [GO:0015755]; negative regulation of ion transmembrane transport [GO:0034766]; positive regulation of cell motility [GO:2000147]; positive regulation of cell size [GO:0045793]; protein tetramerization [GO:0051262]; regulation of cell shape [GO:0008360]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to ischemia [GO:0002931]; response to potassium ion [GO:0035864]; response to salicylic acid [GO:0009751]; response to salt [GO:1902074]; response to thyroid hormone [GO:0097066]; sensory perception of sound [GO:0007605] comp22413_c0_seq1,915,41.7486,0.33914372,1,5,,4.00E-136,Q5EA75,Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),GO:0004306; GO:0006646,ethanolamine-phosphate cytidylyltransferase activity; phosphatidylethanolamine biosynthetic process,PF01467;,3.00E-149,CHOYP_LOC551931.1.1,,,,,,,PCY2_BOVIN,Bos taurus (Bovine),phosphatidylethanolamine biosynthetic process [GO:0006646] comp22413_c0_seq2,942,41.8259,0.35062319,3,0,,4.00E-132,O88637,Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase),GO:0004306; GO:0006646,ethanolamine-phosphate cytidylyltransferase activity; phosphatidylethanolamine biosynthetic process,PF01467;,,,,,,,,,PCY2_RAT,Rattus norvegicus (Rat),phosphatidylethanolamine biosynthetic process [GO:0006646] comp22425_c0_seq1,447,47.2036,0.933338,37,22,,6.00E-15,Q08DV5,E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220),E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220),GO:0005737; GO:0051865; GO:0004842; GO:0008270,cytoplasm; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF15926;,,,,,,,,,RN220_BOVIN,Bos taurus (Bovine),positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567] comp22435_c0_seq1,421,49.4062,0.58660325,4,34,,1.00E-30,Q9VHA0,Polycomb protein Scm (Sex comb on midleg protein),Polycomb protein Scm (Sex comb on midleg protein),GO:0035102; GO:0007409; GO:0016568; GO:0016458; GO:0030708; GO:0045892; GO:0030713; GO:0005700; GO:0006351; GO:0008270,"PRC1 complex; axonogenesis; chromatin modification; gene silencing; germarium-derived female germ-line cyst encapsulation; negative regulation of transcription, DNA-dependent; ovarian follicle cell stalk formation; polytene chromosome; transcription, DNA-dependent; zinc ion binding",PF12140;PF02820;PF00536;PF06467;,,,,,,,,,SCM_DROME,Drosophila melanogaster (Fruit fly),"axonogenesis [GO:0007409]; chromatin modification [GO:0016568]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp22438_c0_seq1,298,63.0872,0.91739669,0,24,,5.00E-13,Q9F234,Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II),Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II),GO:0030246; GO:0005975; GO:0032450,carbohydrate binding; carbohydrate metabolic process; maltose alpha-glucosidase activity,PF16338;PF17137;PF13802;PF01055;,,,,,,,,,AGL2_BACTQ,Bacillus thermoamyloliquefaciens, comp2243_c0_seq1,295,45.7627,0.26311413,3,2,,3.00E-15,O97394,Protein sidekick,Protein sidekick,GO:0007155; GO:0042675; GO:0005887; GO:0046533; GO:0050931,cell adhesion; compound eye cone cell differentiation; integral to plasma membrane; negative regulation of photoreceptor cell differentiation; pigment cell differentiation,PF00041;PF07679;,,,,,,,,,SDK_DROME,Drosophila melanogaster (Fruit fly),cell adhesion [GO:0007155]; compound eye cone cell differentiation [GO:0042675]; negative regulation of photoreceptor cell differentiation [GO:0046533]; pigment cell differentiation [GO:0050931] comp22440_c0_seq1,201,41.2935,0.35192509,0,19,,1.00E-13,Q9DBE0,Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase),Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase),GO:0019452; GO:0016831; GO:0030170; GO:0004782; GO:0042412,L-cysteine catabolic process to taurine; carboxy-lyase activity; pyridoxal phosphate binding; sulfinoalanine decarboxylase activity; taurine biosynthetic process,PF00282;,,,,,,,,,CSAD_MOUSE,Mus musculus (Mouse),L-cysteine catabolic process to taurine [GO:0019452]; taurine biosynthetic process [GO:0042412]; taurine metabolic process [GO:0019530] comp22455_c0_seq1,396,47.7273,0.8083762,10,28,,2.00E-11,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp22456_c0_seq1,938,45.629,0.37065832,24,61,,3.00E-08,Q9HCS5,Band 4.1-like protein 4A (Protein NBL4),Band 4.1-like protein 4A (Protein NBL4),GO:0005737; GO:0005856; GO:0019898,cytoplasm; cytoskeleton; extrinsic to membrane,PF08736;PF09380;PF00373;PF09379;,,,,,,,,,E41LA_HUMAN,Homo sapiens (Human), comp22461_c0_seq1,501,44.9102,0.3607488,10,44,,4.00E-68,B5X3C1,Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase),GO:0005975; GO:0004336; GO:0006683; GO:0005764,carbohydrate metabolic process; galactosylceramidase activity; galactosylceramide catabolic process; lysosome,PF02057;,3.00E-45,CHOYP_LOC100376265.3.4,,,,,,,GALC_SALSA,Salmo salar (Atlantic salmon),carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683] comp22469_c0_seq1,413,44.5521,0.34243377,22,30,,1.00E-47,Q91V92,ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme),ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme),GO:0005524; GO:0003878; GO:0006085; GO:0044262; GO:0048037; GO:0008610; GO:0046872; GO:0005739; GO:0004775,ATP binding; ATP citrate synthase activity; acetyl-CoA biosynthetic process; cellular carbohydrate metabolic process; cofactor binding; lipid biosynthetic process; metal ion binding; mitochondrion; succinate-CoA ligase (ADP-forming) activity,PF16114;PF00285;PF02629;PF00549;,6.00E-40,CHOYP_ACLY.1.1,,,,,,,ACLY_MOUSE,Mus musculus (Mouse),acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107] comp22473_c0_seq1,329,45.8967,0.81655049,8,35,,1.00E-11,Q5EBH1,Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL),Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL),GO:0006915; GO:0005737; GO:0035556; GO:0046872; GO:0005874; GO:0008285; GO:0005634; GO:0031398; GO:1900180,apoptotic process; cytoplasm; intracellular signal transduction; metal ion binding; microtubule; negative regulation of cell proliferation; nucleus; positive regulation of protein ubiquitination; regulation of protein localization to nucleus,PF00130;PF16517;PF00788;,,,,,,,,,RASF5_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; negative regulation of cell proliferation [GO:0008285]; positive regulation of protein ubiquitination [GO:0031398]; regulation of protein localization to nucleus [GO:1900180] comp22474_c0_seq1,708,42.6554,0.46743237,16,52,,9.00E-71,Q9BRC7,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4) (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4) (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)",GO:0007340; GO:0005509; GO:0005783; GO:0035556; GO:0016042; GO:0016020; GO:0005634; GO:0004435; GO:0005543; GO:0004871,acrosome reaction; calcium ion binding; endoplasmic reticulum; intracellular signal transduction; lipid catabolic process; membrane; nucleus; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF13202;PF09279;PF00169;PF00388;PF00387;,3.00E-40,CHOYP_PLCD1.1.1,1.00E-23,ruditapes2_c2698,,,,,PLCD4_HUMAN,Homo sapiens (Human),acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488] comp22482_c0_seq1,316,45.8861,0.4231545,6,17,,7.00E-08,P20241,Neuroglian,Neuroglian,GO:0008366; GO:0048675; GO:0005509; GO:0061343; GO:0048036; GO:0048813; GO:0007173; GO:0060857; GO:0008050; GO:0030175; GO:0007560; GO:0016021; GO:0016328; GO:0008049; GO:0035011; GO:0016319; GO:0021682; GO:0007158; GO:0005919; GO:0045924; GO:0035151; GO:0019991; GO:0050808; GO:0005923,"axon ensheathment; axon extension; calcium ion binding; cell adhesion involved in heart morphogenesis; central complex development; dendrite morphogenesis; epidermal growth factor receptor signaling pathway; establishment of glial blood-brain barrier; female courtship behavior; filopodium; imaginal disc morphogenesis; integral to membrane; lateral plasma membrane; male courtship behavior; melanotic encapsulation of foreign target; mushroom body development; nerve maturation; neuron cell-cell adhesion; pleated septate junction; regulation of female receptivity; regulation of tube size, open tracheal system; septate junction assembly; synapse organization; tight junction",PF13882;PF00041;PF07679;PF00047;,,,,,,,,,NRG_DROME,Drosophila melanogaster (Fruit fly),"axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]" comp22516_c0_seq1,204,62.7451,0.97474815,0,27,,3.00E-13,P78285,Lysozyme RrrD (EC 3.2.1.17) (Endolysin) (Lysis protein) (Muramidase),Lysozyme RrrD (EC 3.2.1.17) (Endolysin) (Lysis protein) (Muramidase),GO:0016998; GO:0019835; GO:0042742; GO:0003796; GO:0009253,cell wall macromolecule catabolic process; cytolysis; defense response to bacterium; lysozyme activity; peptidoglycan catabolic process,PF00959;,,,,,,,,,LYSD_ECOLI,Escherichia coli (strain K12),cell wall macromolecule catabolic process [GO:0016998]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253] comp22525_c0_seq1,363,48.2094,0.42823854,5,25,,1.00E-16,Q96JI7,Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein),Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein),GO:0008219; GO:0031410; GO:0005829; GO:0016021; GO:0005765; GO:0005730; GO:0005886,cell death; cytoplasmic vesicle; cytosol; integral to membrane; lysosomal membrane; nucleolus; plasma membrane,PF14649;,,,,,,,,,SPTCS_HUMAN,Homo sapiens (Human),axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; synaptic vesicle transport [GO:0048489] comp22539_c0_seq1,649,40.2157,0.45833932,8,58,,2.00E-50,P13705,DNA mismatch repair protein Msh3 (Protein repair-1) (REP-1) (Protein repair-3) (REP-3),DNA mismatch repair protein Msh3 (Protein repair-1) (REP-1) (Protein repair-3) (REP-3),GO:0005524; GO:0008094; GO:0032302; GO:0000403; GO:0019237; GO:0003684; GO:0000406; GO:0000404; GO:0043570; GO:0000710; GO:0000228; GO:0007131; GO:0016447,ATP binding; DNA-dependent ATPase activity; MutSbeta complex; Y-form DNA binding; centromeric DNA binding; damaged DNA binding; double-strand/single-strand DNA junction binding; loop DNA binding; maintenance of DNA repeat elements; meiotic mismatch repair; nuclear chromosome; reciprocal meiotic recombination; somatic recombination of immunoglobulin gene segments,PF01624;PF05188;PF05192;PF00488;,3.00E-65,CHOYP_MSH3.1.2,,,,,,,MSH3_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; reciprocal meiotic recombination [GO:0007131]; somatic recombination of immunoglobulin gene segments [GO:0016447] comp22578_c0_seq1,229,46.2882,0.32857769,5,13,,3.00E-16,O00471,Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10),Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10),GO:0044267; GO:0005829; GO:0006887; GO:0006892; GO:0015031; GO:0048278,cellular protein metabolic process; cytosol; exocytosis; post-Golgi vesicle-mediated transport; protein transport; vesicle docking,PF07393;,,,,,,,,,EXOC5_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; vesicle docking [GO:0048278] comp22579_c0_seq1,588,42.517,0.42156411,16,16,,4.00E-31,O94886,Transmembrane protein 63A,CSC1-like protein 1 (Transmembrane protein 63A),GO:0016021; GO:0005765; GO:0000166,integral to membrane; lysosomal membrane; nucleotide binding,PF14703;PF02714;PF13967;,,,,,,,,,TM63A_HUMAN,Homo sapiens (Human),ion transport [GO:0006811] comp22583_c0_seq1,316,44.9367,1.14007136,0,27,,3.00E-28,O97860,Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),GO:0003993; GO:0008199; GO:0008198; GO:0005764,acid phosphatase activity; ferric iron binding; ferrous iron binding; lysosome,PF00149;,,,,,,,,,PPA5_RABIT,Oryctolagus cuniculus (Rabbit), comp22589_c0_seq1,227,60.3524,1.21797235,1,0,,4.00E-15,Q5WL06,Ribulokinase (EC 2.7.1.16),Ribulokinase (EC 2.7.1.16),GO:0005524; GO:0019569; GO:0008741,ATP binding; L-arabinose catabolic process to xylulose 5-phosphate; ribulokinase activity,PF02782;PF00370;,,,,,,,,,ARAB_BACSK,Bacillus clausii (strain KSM-K16),L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569] comp22592_c0_seq1,287,46.6899,0.32542768,5,27,,7.00E-11,O05218,Putative gamma-glutamyltransferase YwrD (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain],Putative gamma-glutamyltransferase YwrD (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain],GO:0003840; GO:0036374; GO:0006749,gamma-glutamyltransferase activity; glutathione hydrolase activity; glutathione metabolic process,PF01019;,6.00E-19,CHOYP_NEMVEDRAFT_V1G169538.2.2,,,,,,,YWRD_BACSU,Bacillus subtilis (strain 168),glutathione metabolic process [GO:0006749] comp22608_c0_seq1,776,44.201,0.30284934,10,39,,2.00E-42,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp22617_c0_seq1,201,50.7463,0.71661214,0,60,,,,,,,,,3.00E-33,CHOYP_LOC100214376.1.1,,,,,,,,, comp22631_c0_seq1,241,43.5685,0.1844544,4,16,,1.00E-27,O14976,Cyclin-G-associated kinase (EC 2.7.11.1),Cyclin-G-associated kinase (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0007049; GO:0005925; GO:0048471; GO:0004674,ATP binding; Golgi apparatus; cell cycle; focal adhesion; perinuclear region of cytoplasm; protein serine/threonine kinase activity,PF00069;PF10409;,,,,,,,,,GAK_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; establishment of protein localization to Golgi [GO:0072600]; establishment of protein localization to plasma membrane [GO:0090002]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; negative regulation of neuron projection development [GO:0010977]; receptor-mediated endocytosis [GO:0006898] comp22634_c0_seq1,524,39.6947,0.32608814,6,29,,1.00E-06,Q8T390,Endophilin-A (SH3 domain-containing GRB2-like protein),Endophilin-A (SH3 domain-containing GRB2-like protein),GO:0005737; GO:0042171; GO:0016020; GO:0007269; GO:0050803; GO:0048488,cytoplasm; lysophosphatidic acid acyltransferase activity; membrane; neurotransmitter secretion; regulation of synapse structure and activity; synaptic vesicle endocytosis,PF03114;PF00018;,,,,,,,,,SH3G3_DROME,Drosophila melanogaster (Fruit fly),membrane tubulation [GO:0097320]; neurotransmitter secretion [GO:0007269]; regulation of synapse structure or activity [GO:0050803]; synaptic vesicle endocytosis [GO:0048488] comp22636_c0_seq1,303,36.3036,0.21491927,4,33,,2.00E-19,Q6NWH0,UPF0696 protein C11orf68 homolog,UPF0696 protein C11orf68 homolog,,,PF08939;,,,,,,,,,CK068_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp22648_c0_seq1,232,37.931,0.7254935,7,20,,9.00E-10,O35382,Exocyst complex component 4 (Exocyst complex component Sec8),Exocyst complex component 4 (Exocyst complex component Sec8),GO:0000145; GO:0032584; GO:0035748; GO:0015031; GO:0006904,exocyst; growth cone membrane; myelin sheath abaxonal region; protein transport; vesicle docking involved in exocytosis,PF04048;,1.00E-19,CHOYP_EXOC4.2.2,,,,,,,EXOC4_MOUSE,Mus musculus (Mouse),membrane organization [GO:0061024]; paraxial mesoderm formation [GO:0048341]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904] comp22653_c0_seq1,254,49.2126,0.47933074,0,33,,9.00E-17,A5GZY1,Neuromacin-like protein,Neuromacin-like protein,GO:0005576,extracellular region,PF14865;,,,,,,,,,NEURM_APLCA,Aplysia californica (California sea hare),defense response [GO:0006952] comp22658_c0_seq1,403,55.335,0.8116945,9,17,,,,,,,,,3.00E-11,CHOYP_ATS2.2.2,,,,,,,,, comp22659_c0_seq1,510,44.7059,0.95254735,7,30,,1.00E-50,P28039,Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit],Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit],GO:0050528; GO:0005576; GO:0006954; GO:0006629; GO:0008653; GO:0004465; GO:0050728,acyloxyacyl hydrolase activity; extracellular region; inflammatory response; lipid metabolic process; lipopolysaccharide metabolic process; lipoprotein lipase activity; negative regulation of inflammatory response,PF00657;PF03489;,2.00E-14,CHOYP_MONBRDRAFT_34989.1.1,,,,,,,AOAH_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629] comp22675_c0_seq1,445,40,0.80547362,12,27,,2.00E-10,Q6IE52,Murinoglobulin-2,Murinoglobulin-2,GO:0005615; GO:0010951; GO:0004867,extracellular space; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,MUG2_RAT,Rattus norvegicus (Rat), comp22679_c0_seq1,225,40,0.78473772,7,20,,,,,,,,,1.00E-14,CHOYP_PHUM_PHUM215460.1.1,,,,,,,,, comp22690_c0_seq1,316,45.2532,0.87328698,11,20,,1.00E-22,Q7QH73,Chorion peroxidase (EC 1.11.1.7),Chorion peroxidase (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;,,,,,,,,,PERC_ANOGA,Anopheles gambiae (African malaria mosquito),hydrogen peroxide catabolic process [GO:0042744]; oogenesis [GO:0048477]; response to oxidative stress [GO:0006979] comp22698_c0_seq1,201,51.7413,0.58552174,3,12,,1.00E-18,Q3T906,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0046835; GO:0030154; GO:0016021; GO:0005634; GO:0009306,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; carbohydrate phosphorylation; cell differentiation; integral to membrane; nucleus; protein secretion,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,,,,,,,,,GNPTA_HUMAN,Homo sapiens (Human),carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; protein secretion [GO:0009306] comp22725_c0_seq1,444,43.018,0.58591476,5,19,,3.00E-38,Q96PB1,CAS1 domain-containing protein 1,CAS1 domain-containing protein 1,GO:0016021,integral to membrane,PF07779;,,,,,,,,,CASD1_HUMAN,Homo sapiens (Human), comp22763_c0_seq1,219,43.379,1.0727174,0,15,,4.00E-15,Q64403,Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16),Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2DG_CAVPO,Cavia porcellus (Guinea pig), comp22766_c0_seq1,300,42.3333,1.12035984,2,29,,1.00E-27,Q6RUV5,Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),GO:0005525; GO:0003924; GO:0000139; GO:0016601; GO:0060071; GO:0007015; GO:0048532; GO:0002093; GO:0007411; GO:0045453; GO:0008283; GO:0045216; GO:0021799; GO:0090103; GO:0031410; GO:0048813; GO:0071542; GO:0021831; GO:0043652; GO:0003382; GO:0019897; GO:0006972; GO:0030027; GO:0030032; GO:0002551; GO:0042470; GO:0001891; GO:0045740; GO:0030838; GO:0043552; GO:0001934; GO:0030334; GO:0097178; GO:0032587; GO:0034446,"GTP binding; GTPase activity; Golgi membrane; Rac protein signal transduction; Wnt receptor signaling pathway, planar cell polarity pathway; actin filament organization; anatomical structure arrangement; auditory receptor cell morphogenesis; axon guidance; bone resorption; cell proliferation; cell-cell junction organization; cerebral cortex radially oriented cell migration; cochlea morphogenesis; cytoplasmic vesicle; dendrite morphogenesis; dopaminergic neuron differentiation; embryonic olfactory bulb interneuron precursor migration; engulfment of apoptotic cell; epithelial cell morphogenesis; extrinsic to plasma membrane; hyperosmotic response; lamellipodium; lamellipodium assembly; mast cell chemotaxis; melanosome; phagocytic cup; positive regulation of DNA replication; positive regulation of actin filament polymerization; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of protein phosphorylation; regulation of cell migration; ruffle assembly; ruffle membrane; substrate adhesion-dependent cell spreading",PF00071;,,,,,,,,,RAC1_RAT,Rattus norvegicus (Rat),"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp22768_c0_seq1,412,41.7476,0.33509325,12,10,,6.00E-19,Q8C827,Zinc finger protein 62 (Zfp-62) (ZT3),Zinc finger protein 62 (Zfp-62) (ZT3),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZFP62_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp22770_c0_seq1,296,38.5135,0.27457941,8,18,,6.00E-30,O76924,Protein ariadne-2 (Ari-2),Protein ariadne-2 (Ari-2),GO:0003676; GO:0005634; GO:0008270,nucleic acid binding; nucleus; zinc ion binding,PF01485;,7.00E-37,CHOYP_ARI2.1.1,,,,,,,ARI2_DROME,Drosophila melanogaster (Fruit fly),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp22782_c0_seq1,215,39.0698,0.49684801,0,6,,2.00E-15,Q8C5D8,E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),GO:0003677; GO:0016605; GO:0019789; GO:0050681; GO:0060766; GO:0016604; GO:0016607; GO:0045944; GO:0016925; GO:0060765; GO:0045667; GO:0006355; GO:0006351; GO:0008270,"DNA binding; PML body; SUMO ligase activity; androgen receptor binding; negative regulation of androgen receptor signaling pathway; nuclear body; nuclear speck; positive regulation of transcription from RNA polymerase II promoter; protein sumoylation; regulation of androgen receptor signaling pathway; regulation of osteoblast differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS2_MOUSE,Mus musculus (Mouse),"negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp22782_c0_seq2,221,35.7466,0.44758981,1,8,,3.00E-10,Q9JM05,E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma),E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma),GO:0003677; GO:0007259; GO:0016605; GO:0019789; GO:0016055; GO:0005737; GO:0019048; GO:0007275; GO:0032088; GO:0000122; GO:0016363; GO:1902231; GO:1902174; GO:0033235; GO:0016925; GO:0003714; GO:0006351; GO:0008270,"DNA binding; JAK-STAT cascade; PML body; SUMO ligase activity; Wnt receptor signaling pathway; cytoplasm; modulation by virus of host morphology or physiology; multicellular organismal development; negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; nuclear matrix; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of keratinocyte apoptotic process; positive regulation of protein sumoylation; protein sumoylation; transcription corepressor activity; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS4_MOUSE,Mus musculus (Mouse),"JAK-STAT cascade [GO:0007259]; multicellular organism development [GO:0007275]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]" comp22834_c0_seq1,1101,46.2307,0.46299677,48,36,,2.00E-82,P09851,Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),GO:0051020; GO:0005099; GO:0000910; GO:0005737; GO:0009790; GO:0031235; GO:0046580; GO:0001953; GO:0043524; GO:0005543; GO:0005102; GO:0030833; GO:0007165; GO:0001570,GTPase binding; Ras GTPase activator activity; cytokinesis; cytoplasm; embryo development; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; negative regulation of cell-matrix adhesion; negative regulation of neuron apoptotic process; phospholipid binding; receptor binding; regulation of actin filament polymerization; signal transduction; vasculogenesis,PF00168;PF00169;PF00616;PF00017;PF00018;,3.00E-62,CHOYP_LOC100875369.1.1,,,,,,,RASA1_BOVIN,Bos taurus (Bovine),embryo development [GO:0009790]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] comp22840_c0_seq1,361,47.3684,0.95821298,5,27,,2.00E-13,Q8ELR0,NAD-dependent protein deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog),NAD-dependent protein deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog),GO:0070403; GO:0005737; GO:0016787; GO:0046872,NAD+ binding; cytoplasm; hydrolase activity; metal ion binding,PF02146;,,,,,,,,,NPD_OCEIH,Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831), comp2287_c0_seq1,344,36.0465,0.63419654,5,5,,2.00E-17,Q9H160,Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2),Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2),GO:0016602; GO:0003677; GO:0016580; GO:0003682; GO:0016568; GO:0048133; GO:0007141; GO:0035064; GO:0043066; GO:1902166; GO:0035091; GO:0045893; GO:0030511; GO:0032403; GO:2000772; GO:0040008; GO:0072520; GO:0007165; GO:0030317; GO:0007286; GO:0006351; GO:0008270,"CCAAT-binding factor complex; DNA binding; Sin3 complex; chromatin binding; chromatin modification; male germ-line stem cell division; male meiosis I; methylated histone residue binding; negative regulation of apoptotic process; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; phosphatidylinositol binding; positive regulation of transcription, DNA-dependent; positive regulation of transforming growth factor beta receptor signaling pathway; protein complex binding; regulation of cellular senescence; regulation of growth; seminiferous tubule development; signal transduction; sperm motility; spermatid development; transcription, DNA-dependent; zinc ion binding",PF12998;,,,,,,,,,ING2_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; male germ-line stem cell asymmetric division [GO:0048133]; male meiosis I [GO:0007141]; negative regulation of cell proliferation [GO:0008285]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cellular senescence [GO:2000772]; regulation of growth [GO:0040008]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription, DNA-templated [GO:0006355]; seminiferous tubule development [GO:0072520]; signal transduction [GO:0007165]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]" comp22887_c0_seq1,315,49.5238,0.31919514,8,25,,,,,,,,,2.00E-20,CHOYP_DYH8.2.2,,,,,,,,, comp22890_c0_seq1,361,43.4903,0.88121416,17,10,,2.00E-31,Q5TZ24,DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-),DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,4.00E-20,ruditapes_c8290,,,,,MOXD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp22892_c0_seq1,462,46.7532,0.55577728,17,11,,3.00E-79,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-105,CHOYP_DNAH5.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp22894_c0_seq1,312,42.6282,0.35439676,4,28,,4.00E-26,Q6PB70,Anoctamin-8 (Transmembrane protein 16H),Anoctamin-8 (Transmembrane protein 16H),GO:0016021; GO:0005622; GO:0005886,integral to membrane; intracellular; plasma membrane,PF04547;,1.00E-28,CHOYP_LOC100882952.1.1,,,,,,,ANO8_MOUSE,Mus musculus (Mouse),chloride transport [GO:0006821] comp22914_c0_seq1,228,45.614,0.60083615,0,25,,1.00E-13,Q5RER9,Zinc finger protein 813,Zinc finger protein 813,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,2.00E-11,CHOYP_AGAP_AGAP009899.1.1,,,,,,,ZN813_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp22921_c0_seq1,767,41.4602,0.85397866,18,27,,5.00E-35,A1XQX2,Neurexin-1b (Neurexin Ib-alpha) (Neurexin-1b-alpha),Neurexin-1b (Neurexin Ib-alpha) (Neurexin-1b-alpha),GO:0007155; GO:0016021; GO:0046872; GO:0007269; GO:0051965; GO:0090129; GO:0007416,cell adhesion; integral to membrane; metal ion binding; neurotransmitter secretion; positive regulation of synapse assembly; positive regulation of synapse maturation; synapse assembly,PF02210;PF01034;,,,,,,,,,NR1BA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155] comp22923_c0_seq1,211,45.4976,0.27797827,10,9,,1.00E-18,Q98SP7,Bardet-Biedl syndrome 2 protein homolog,Bardet-Biedl syndrome 2 protein homolog,GO:0070121; GO:0042384; GO:0060170; GO:0005737; GO:0007368; GO:0046907; GO:0032402; GO:0005815; GO:0051877,Kupffer's vesicle development; cilium assembly; cilium membrane; cytoplasm; determination of left/right symmetry; intracellular transport; melanosome transport; microtubule organizing center; pigment granule aggregation in cell center,PF14782;PF14783;PF14781;,,,,,,,,,BBS2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; nonmotile primary cilium assembly [GO:0035058]; pigment granule aggregation in cell center [GO:0051877]; protein localization to ciliary membrane [GO:1903441] comp22936_c0_seq1,328,39.0244,0.48621142,10,0,,4.00E-12,P08F94,Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin),GO:0031362; GO:0016324; GO:0016337; GO:0005813; GO:0042384; GO:0005737; GO:0042592; GO:0016021; GO:0001822; GO:0005932; GO:0072686; GO:0051271; GO:0072372; GO:0004872; GO:0010824,anchored to external side of plasma membrane; apical plasma membrane; cell-cell adhesion; centrosome; cilium assembly; cytoplasm; homeostatic process; integral to membrane; kidney development; microtubule basal body; mitotic spindle; negative regulation of cellular component movement; primary cilium; receptor activity; regulation of centrosome duplication,PF10162;PF01833;,,,,,,,,,PKHD1_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337] comp22947_c0_seq1,285,39.2982,0.73053262,0,31,,8.00E-16,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp22955_c0_seq1,317,41.6404,0.66250659,8,6,,2.00E-21,Q460N3,Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),GO:0003950; GO:0005634; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR15_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp22985_c0_seq1,308,51.2987,0.69361001,10,24,,2.00E-12,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp22994_c0_seq1,358,49.7207,0.77292903,4,24,,5.00E-10,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,,,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp22997_c0_seq1,567,47.619,0.65463131,15,21,,1.00E-57,Q60954,Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1),Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1),GO:0003677; GO:0003705; GO:0001525; GO:0048514; GO:0003682; GO:0060216; GO:0002089; GO:0045638; GO:0045665; GO:0005634; GO:0006357; GO:0043565; GO:0005667,DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; angiogenesis; blood vessel morphogenesis; chromatin binding; definitive hemopoiesis; lens morphogenesis in camera-type eye; negative regulation of myeloid cell differentiation; negative regulation of neuron differentiation; nucleus; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription factor complex,PF05920;PF16493;,1.00E-68,CHOYP_LOC100374249.1.1,,,,,,,MEIS1_MOUSE,Mus musculus (Mouse),"angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; definitive hemopoiesis [GO:0060216]; hemopoiesis [GO:0030097]; lens morphogenesis in camera-type eye [GO:0002089]; locomotory behavior [GO:0007626]; megakaryocyte development [GO:0035855]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]" comp23032_c0_seq1,229,64.6288,1.40246577,0,22,,3.00E-16,Q58318,Uncharacterized protein MJ0908,Uncharacterized protein MJ0908,GO:0015995; GO:0009236; GO:0051116; GO:0016851,chlorophyll biosynthetic process; cobalamin biosynthetic process; cobaltochelatase activity; magnesium chelatase activity,PF02514;,,,,,,,,,Y908_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),chlorophyll biosynthetic process [GO:0015995]; cobalamin biosynthetic process [GO:0009236] comp23047_c0_seq1,290,46.5517,0.7983634,12,16,,1.00E-13,Q0VH32,Max-binding protein MNT (Myc antagonist MNT),Max-binding protein MNT (Myc antagonist MNT),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00010;,,,,,,,,,MNT_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp23054_c0_seq1,216,46.2963,0.52416582,9,14,,6.00E-21,P48067,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),GO:0015375; GO:0005887; GO:0005328,glycine:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,SC6A9_HUMAN,Homo sapiens (Human),"glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp23074_c0_seq1,494,34.8178,0.81414807,1,61,,2.00E-20,Q9QZP2,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0071363; GO:0031670; GO:0005829; GO:0046872; GO:0008168; GO:0030308; GO:0005654; GO:0006355; GO:0006351,"DNA binding; cellular response to growth factor stimulus; cellular response to nutrient; cytosol; metal ion binding; methyltransferase activity; negative regulation of cell growth; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_RAT,Rattus norvegicus (Rat),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp23089_c0_seq1,365,42.1918,0.61897979,7,8,,8.00E-41,Q920L7,Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (rELO1) (Very-long-chain 3-oxoacyl-CoA synthase 5),Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (rELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5),GO:0005789; GO:0009922; GO:0034625; GO:0034626; GO:0016021; GO:0006636; GO:0042761,"endoplasmic reticulum membrane; fatty acid elongase activity; fatty acid elongation, monounsaturated fatty acid; fatty acid elongation, polyunsaturated fatty acid; integral to membrane; unsaturated fatty acid biosynthetic process; very long-chain fatty acid biosynthetic process",PF01151;,,,,,,,,,ELOV5_RAT,Rattus norvegicus (Rat),"fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761]" comp23089_c0_seq2,363,42.4242,0.67578572,0,0,,4.00E-58,Q3S8M4,Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very-long-chain 3-oxoacyl-CoA synthase 4),Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4),GO:0019367; GO:0030176; GO:0016740; GO:0042761,"fatty acid elongation, saturated fatty acid; integral to endoplasmic reticulum membrane; transferase activity; very long-chain fatty acid biosynthetic process",PF01151;,2.00E-76,CHOYP_ELOV4.1.3,,,,,,,ELOV4_MACMU,Macaca mulatta (Rhesus macaque),"fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]" comp23125_c0_seq1,301,41.196,0.94376042,4,37,,9.00E-46,P84082,ADP-ribosylation factor 2,ADP-ribosylation factor 2,GO:0005525; GO:0005794; GO:0015031; GO:0007264; GO:0016192,GTP binding; Golgi apparatus; protein transport; small GTPase mediated signal transduction; vesicle-mediated transport,PF00025;,1.00E-15,CHOYP_ARF4.1.2,2.00E-17,ruditapes_c19850,,,,,ARF2_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp23142_c0_seq1,656,39.939,0.5677791,34,20,,4.00E-32,Q6DCF6,EF-hand calcium-binding domain-containing protein 7,EF-hand calcium-binding domain-containing protein 7,GO:0005509,calcium ion binding,PF13202;PF13499;,9.00E-53,CHOYP_EFCB7.1.1,2.00E-91,ruditapes2_c2200,,,,,EFCB7_XENLA,Xenopus laevis (African clawed frog), comp23154_c0_seq1,402,44.7761,0.44800178,8,42,,1.00E-08,Q28EH9,Transmembrane protein 194A,Nuclear envelope integral membrane protein 1,GO:0016021,integral to membrane,PF10225;,,,,,,,,,T194A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),eye development [GO:0001654] comp23158_c0_seq1,411,42.0925,0.27643749,11,15,,2.00E-27,Q9HBF4,Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1),Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1),GO:0005545; GO:0005795; GO:0005783; GO:0010923; GO:0048471; GO:0005547; GO:0043325; GO:0008270,"1-phosphatidylinositol binding; Golgi stack; endoplasmic reticulum; negative regulation of phosphatase activity; perinuclear region of cytoplasm; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; zinc ion binding",PF01363;,2.00E-26,CHOYP_LOC100375831.1.1,,,,,,,ZFYV1_HUMAN,Homo sapiens (Human),cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923] comp23162_c0_seq1,211,43.6019,0.42064437,5,10,,9.00E-10,Q19546,Probable Werner syndrome ATP-dependent helicase homolog 1 (EC 3.6.4.12),Probable Werner syndrome ATP-dependent helicase homolog 1 (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0005694; GO:0008340; GO:0040007; GO:0005654; GO:0010212,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA binding; DNA recombination; DNA repair; DNA replication; chromosome; determination of adult lifespan; growth; nucleoplasm; response to ionizing radiation,PF00270;PF00271;PF00570;PF14493;PF16124;PF09382;,,,,,,,,,WRN_CAEEL,Caenorhabditis elegans,base-excision repair [GO:0006284]; cell aging [GO:0007569]; cellular response to gamma radiation [GO:0071480]; determination of adult lifespan [GO:0008340]; DNA metabolic process [GO:0006259]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; growth [GO:0040007]; replication fork processing [GO:0031297]; response to ionizing radiation [GO:0010212]; telomere maintenance via recombination [GO:0000722] comp23163_c0_seq1,275,41.0909,0.28356539,8,31,,9.00E-15,Q6DN14,Multiple C2 and transmembrane domain-containing protein 1,Multiple C2 and transmembrane domain-containing protein 1,GO:0005509; GO:0019722; GO:0016021,calcium ion binding; calcium-mediated signaling; integral to membrane,PF00168;PF08372;,7.00E-24,CHOYP_LOC100748072.1.1,,,,,,,MCTP1_HUMAN,Homo sapiens (Human),calcium-mediated signaling [GO:0019722] comp23169_c0_seq1,463,44.0605,0.58179284,13,29,,8.00E-42,Q803S3,Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1),Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1),,,PF01875;,2.00E-33,CHOYP_BRAFLDRAFT_114006.1.1,,,,,,,MEMO1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp2316_c0_seq1,213,48.8263,0.80211663,4,0,,2.00E-09,Q61549,EGF-like module-containing mucin-like hormone receptor-like 1 (Cell surface glycoprotein F4/80) (EGF-like module receptor 1) (EMR1 hormone receptor),Adhesion G protein-coupled receptor E1 (Cell surface glycoprotein F4/80) (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor),GO:0004930; GO:0005509; GO:0009897; GO:0016021; GO:0007218,G-protein coupled receptor activity; calcium ion binding; external side of plasma membrane; integral to membrane; neuropeptide signaling pathway,PF00002;PF12662;PF07645;PF01825;,,,,,,,,,EMR1_MOUSE,Mus musculus (Mouse),adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166] comp23174_c0_seq1,252,59.9206,1.24326282,0,30,,1.00E-21,Q9HMM6,Probable cysteine desulfurase (EC 2.8.1.7),Probable cysteine desulfurase (EC 2.8.1.7),GO:0031071; GO:0006534; GO:0030170,cysteine desulfurase activity; cysteine metabolic process; pyridoxal phosphate binding,PF00266;,,,,,,,,,CSD_HALSA,Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium),cysteine metabolic process [GO:0006534] comp23184_c0_seq1,247,45.3441,0.55641938,4,19,,5.00E-39,Q9BZF1,Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8),Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8),GO:0015485; GO:0045444; GO:0006869; GO:0010891; GO:0005543,cholesterol binding; fat cell differentiation; lipid transport; negative regulation of sequestering of triglyceride; phospholipid binding,PF01237;PF00169;,6.00E-37,CHOYP_OSBPL8.1.1,,,,,,,OSBL8_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] comp23231_c0_seq1,202,56.9307,1.30131394,0,22,,3.00E-06,Q31G32,Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase),Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase),GO:0004563; GO:0005975; GO:0007049; GO:0051301; GO:0005737; GO:0009252; GO:0009254; GO:0008360,beta-N-acetylhexosaminidase activity; carbohydrate metabolic process; cell cycle; cell division; cytoplasm; peptidoglycan biosynthetic process; peptidoglycan turnover; regulation of cell shape,PF00933;,,,,,,,,,NAGZ_THICR,Thiomicrospira crunogena (strain XCL-2),carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360] comp23238_c0_seq1,316,45.2532,1.06587302,2,20,,6.00E-09,O75343,Guanylate cyclase soluble subunit beta-2 (GCS-beta-2) (EC 4.6.1.2),Guanylate cyclase soluble subunit beta-2 (GCS-beta-2) (EC 4.6.1.2),GO:0005525; GO:0007596; GO:0005737; GO:0004383; GO:0020037; GO:0035556; GO:0046872,GTP binding; blood coagulation; cytoplasm; guanylate cyclase activity; heme binding; intracellular signal transduction; metal ion binding,PF00211;PF07700;PF07701;,,,,,,,,,GCYB2_HUMAN,Homo sapiens (Human),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165] comp23239_c0_seq1,462,41.5584,0.40300483,8,27,,9.00E-52,Q66L58,Protein VAC14 homolog,Protein VAC14 homolog,GO:0010008; GO:0019209,endosome membrane; kinase activator activity,PF12755;PF11916;,2.00E-46,CHOYP_VAC14.1.1,,,,,,,VAC14_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of lipid kinase activity [GO:0043550] comp23242_c0_seq1,410,43.9024,0.60088077,0,48,,9.00E-27,Q95T12,Calcium channel flower (3L5),Calcium channel flower (3L5),GO:0005262; GO:0030054; GO:0044214; GO:0030285; GO:0046530; GO:0042981; GO:0048488,calcium channel activity; cell junction; fully spanning plasma membrane; integral to synaptic vesicle membrane; photoreceptor cell differentiation; regulation of apoptotic process; synaptic vesicle endocytosis,PF10233;,5.00E-15,CHOYP_CBG07654.1.1,,,,,,,FLOWR_DROME,Drosophila melanogaster (Fruit fly),cell competition in a multicellular organism [GO:0035212]; photoreceptor cell differentiation [GO:0046530]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic process [GO:0042981]; synaptic vesicle endocytosis [GO:0048488] comp23255_c0_seq1,940,44.8936,0.33989563,39,52,,2.00E-51,P54731,FAS-associated factor 1,FAS-associated factor 1,GO:0034098; GO:0006915; GO:0008219; GO:0007253; GO:0005829; GO:0031072; GO:0005635; GO:0048471; GO:1902043; GO:0031334; GO:0019901; GO:0030155; GO:0042176,Cdc48p-Npl4p-Ufd1p AAA ATPase complex; apoptotic process; cell death; cytoplasmic sequestering of NF-kappaB; cytosol; heat shock protein binding; nuclear envelope; perinuclear region of cytoplasm; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of protein complex assembly; protein kinase binding; regulation of cell adhesion; regulation of protein catabolic process,PF00789;,,,,,,,,,FAF1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176] comp23258_c0_seq1,217,44.7005,0.50231481,0,24,,3.00E-19,P51798,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0005254; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; chloride channel activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,5.00E-18,CHOYP_CLCN7.3.3,,,,,,,CLCN7_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810] comp23260_c0_seq1,237,49.789,1.02676548,0,29,,2.00E-19,Q9Z110,Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)],Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)],GO:0005524; GO:0055129; GO:0019240; GO:0004349; GO:0006536; GO:0004350; GO:0005743; GO:0005739; GO:0006592; GO:0006561,ATP binding; L-proline biosynthetic process; citrulline biosynthetic process; glutamate 5-kinase activity; glutamate metabolic process; glutamate-5-semialdehyde dehydrogenase activity; mitochondrial inner membrane; mitochondrion; ornithine biosynthetic process; proline biosynthetic process,PF00696;PF00171;,3.00E-15,CHOYP_LOC100120123.1.1,,,,,,,P5CS_MOUSE,Mus musculus (Mouse),cellular amino acid biosynthetic process [GO:0008652]; citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; ornithine biosynthetic process [GO:0006592]; proline biosynthetic process [GO:0006561] comp23272_c0_seq1,364,40.9341,0.32883131,6,0,,1.00E-42,Q80U30,Protein CLEC16A,Protein CLEC16A,,,PF09758;,3.00E-37,CHOYP_LOC410511.2.2,,,,,,,CL16A_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; negative regulation of macromitophagy [GO:1901525]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of autophagosome maturation [GO:1901098] comp23272_c1_seq1,305,48.8525,0.66522454,2,16,,1.00E-28,P46578,Uncharacterized protein gop-1,Protein CLEC16A homolog,,,PF09758;,,,,,,,,,GOP1_CAEEL,Caenorhabditis elegans,autophagy [GO:0006914] comp23294_c0_seq1,588,40.3061,0.51456177,18,10,,7.00E-15,Q9WU60,Attractin (Protein mahogany),Attractin (Protein mahogany),GO:0030246; GO:0021549; GO:0005737; GO:0005615; GO:0006954; GO:0016021; GO:0042552; GO:0043473; GO:0005886; GO:0004872; GO:0040014; GO:0006979,carbohydrate binding; cerebellum development; cytoplasm; extracellular space; inflammatory response; integral to membrane; myelination; pigmentation; plasma membrane; receptor activity; regulation of multicellular organism growth; response to oxidative stress,PF00431;PF01344;PF00059;PF01437;,1.00E-24,CHOYP_LOC100871946.1.1,,,,,,,ATRN_MOUSE,Mus musculus (Mouse),cerebellum development [GO:0021549]; inflammatory response [GO:0006954]; myelination [GO:0042552]; pigmentation [GO:0043473]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979] comp23297_c0_seq1,216,42.5926,0.43509704,8,6,,,,,,,,,3.00E-15,CHOYP_LOC100367232.2.5,,,,,,,,, comp23314_c0_seq1,304,43.4211,0.35082045,19,0,,4.00E-43,P63031,Mitochondrial pyruvate carrier 1 (Apoptosis-regulating basic protein) (Brain protein 44-like protein),Mitochondrial pyruvate carrier 1 (Apoptosis-regulating basic protein) (Brain protein 44-like protein),GO:0016021; GO:0005743; GO:0006850,integral to membrane; mitochondrial inner membrane; mitochondrial pyruvate transport,PF03650;,,,4.00E-70,ruditapes_c13924,,,,,MPC1_RAT,Rattus norvegicus (Rat),mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; mitochondrial pyruvate transmembrane transport [GO:1902361] comp23350_c0_seq1,849,46.0542,0.38314737,31,9,,4.00E-46,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,3.00E-53,CHOYP_BRAFLDRAFT_251779.2.2,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp23361_c0_seq1,468,39.7436,0.65071404,15,17,,3.00E-06,Q15831,Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19),Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19),GO:0005524; GO:0051645; GO:0032147; GO:0043276; GO:0006914; GO:0007409; GO:0060070; GO:0007050; GO:0005737; GO:0005829; GO:0006112; GO:0030010; GO:0042593; GO:0008286; GO:0072332; GO:0000287; GO:0016020; GO:0005739; GO:0030308; GO:0008285; GO:0060770; GO:0005634; GO:0002039; GO:0050772; GO:0045722; GO:0030511; GO:0046777; GO:0043234; GO:0051291; GO:0030295; GO:0004674; GO:0030111; GO:0042304; GO:0051896; GO:0006974; GO:0033762; GO:0010212; GO:0033993; GO:0044281; GO:0007286; GO:0001894; GO:0001944,ATP binding; Golgi localization; activation of protein kinase activity; anoikis; autophagy; axonogenesis; canonical Wnt receptor signaling pathway; cell cycle arrest; cytoplasm; cytosol; energy reserve metabolic process; establishment of cell polarity; glucose homeostasis; insulin receptor signaling pathway; intrinsic apoptotic signaling pathway by p53 class mediator; magnesium ion binding; membrane; mitochondrion; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation involved in prostate gland development; nucleus; p53 binding; positive regulation of axonogenesis; positive regulation of gluconeogenesis; positive regulation of transforming growth factor beta receptor signaling pathway; protein autophosphorylation; protein complex; protein heterooligomerization; protein kinase activator activity; protein serine/threonine kinase activity; regulation of Wnt receptor signaling pathway; regulation of fatty acid biosynthetic process; regulation of protein kinase B signaling cascade; response to DNA damage stimulus; response to glucagon stimulus; response to ionizing radiation; response to lipid; small molecule metabolic process; spermatid development; tissue homeostasis; vasculature development,PF00069;,,,8.00E-18,ruditapes_c14804,,,,,STK11_HUMAN,Homo sapiens (Human),activation of protein kinase activity [GO:0032147]; anoikis [GO:0043276]; autophagy [GO:0006914]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV-B [GO:0071493]; dendrite extension [GO:0097484]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; Golgi localization [GO:0051645]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; positive regulation of axonogenesis [GO:0050772]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of dendrite morphogenesis [GO:0048814]; regulation of protein kinase B signaling [GO:0051896]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; T cell receptor signaling pathway [GO:0050852]; TCR signalosome assembly [GO:0036399]; tissue homeostasis [GO:0001894]; vasculature development [GO:0001944] comp23370_c0_seq1,427,45.4333,0.23301522,9,14,,3.00E-19,Q7L1I2,Synaptic vesicle glycoprotein 2B,Synaptic vesicle glycoprotein 2B,GO:0001669; GO:0030054; GO:0016021; GO:0006836; GO:0030672; GO:0022857,acrosomal vesicle; cell junction; integral to membrane; neurotransmitter transport; synaptic vesicle membrane; transmembrane transporter activity,PF07690;PF13599;PF00083;,5.00E-66,CHOYP_LOC582715.1.1,,,,,,,SV2B_HUMAN,Homo sapiens (Human),neurotransmitter transport [GO:0006836] comp23375_c0_seq1,742,47.4394,0.19724609,44,4,,7.00E-81,Q03460,"Glutamate synthase [NADH], amyloplastic (EC 1.4.1.14) (NADH-GOGAT)","Glutamate synthase [NADH], amyloplastic (EC 1.4.1.14) (NADH-GOGAT)",GO:0051538; GO:0010181; GO:0097054; GO:0009501; GO:0050660; GO:0016040; GO:0006541; GO:0005506,"3 iron, 4 sulfur cluster binding; FMN binding; L-glutamate biosynthetic process; amyloplast; flavin adenine dinucleotide binding; glutamate synthase (NADH) activity; glutamine metabolic process; iron ion binding",PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;,9.00E-85,CHOYP_BRAFLDRAFT_129259.1.1,,,,,,,GLSN_MEDSA,Medicago sativa (Alfalfa),glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054] comp23410_c0_seq1,282,43.617,0.53167604,5,11,,9.00E-30,O60499,Syntaxin-10 (Syn10),Syntaxin-10 (Syn10),GO:0000139; GO:0048193; GO:0005484; GO:0031201; GO:0016021; GO:0006886; GO:0042147; GO:0006906,"Golgi membrane; Golgi vesicle transport; SNAP receptor activity; SNARE complex; integral to membrane; intracellular protein transport; retrograde transport, endosome to Golgi; vesicle fusion",PF05739;PF09177;,4.00E-27,CHOYP_LOC100367266.1.1,,,,,,,STX10_HUMAN,Homo sapiens (Human),"Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]" comp23411_c0_seq1,263,47.5285,0.34976658,4,15,,4.00E-20,Q08D64,"ATP-binding cassette sub-family B member 6, mitochondrial","ATP-binding cassette sub-family B member 6, mitochondrial",GO:0005524; GO:0006200; GO:0042626; GO:0005794; GO:0005783; GO:0016021; GO:0005741; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; Golgi apparatus; endoplasmic reticulum; integral to membrane; mitochondrial outer membrane; plasma membrane",PF00664;PF00005;PF16185;,,,,,,,,,ABCB6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp23413_c0_seq1,259,42.8571,0.67533474,6,11,,3.00E-09,Q06649,SH3 domain-binding protein 2 (3BP-2),SH3 domain-binding protein 2 (3BP-2),GO:0005543,phospholipid binding,PF00169;PF00017;,,,,,,,,,3BP2_MOUSE,Mus musculus (Mouse), comp23426_c0_seq1,238,30.6723,0.71773039,5,10,,2.00E-07,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp23448_c0_seq1,227,68.2819,1.22624228,0,12,,8.00E-18,P52147,Arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier),Arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier),GO:0008794; GO:0046685,arsenate reductase (glutaredoxin) activity; response to arsenic-containing substance,PF03960;,,,,,,,,,ARSC2_ECOLX,Escherichia coli,response to arsenic-containing substance [GO:0046685] comp23452_c0_seq1,645,44.186,0.92285936,4,41,,2.00E-50,Q6NT55,Cytochrome P450 4F22 (EC 1.14.14.-),Cytochrome P450 4F22 (EC 1.14.14.-),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,6.00E-17,CHOYP_BRAFLDRAFT_58592.1.2,,,,,,,CP4FN_HUMAN,Homo sapiens (Human),icosanoid metabolic process [GO:0006690] comp23509_c0_seq1,221,55.6561,0.837753,0,11,,1.00E-06,Q00750,Multiple sugar-binding transport system permease protein MsmF,Multiple sugar-binding transport system permease protein MsmF,GO:0008643; GO:0016021; GO:0005886; GO:0005215,carbohydrate transport; integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,MSMF_STRMU,Streptococcus mutans serotype c (strain ATCC 700610 / UA159),carbohydrate transport [GO:0008643] comp23521_c0_seq1,597,46.3987,0.31520223,22,16,,6.00E-51,A0JPG1,Protein FAM160B1,Protein FAM160B1,,,PF10257;,2.00E-29,CHOYP_F16B1.1.1,,,,,,,F16B1_XENLA,Xenopus laevis (African clawed frog), comp23529_c0_seq1,214,36.4486,0.88540025,4,8,,6.00E-09,Q290X1,Sugar transporter SWEET1 (Protein saliva),Sugar transporter SWEET1 (Protein saliva),GO:0000139; GO:0016021; GO:0005886; GO:0007431; GO:0051119,Golgi membrane; integral to membrane; plasma membrane; salivary gland development; sugar transmembrane transporter activity,PF03083;,,,,,,,,,SWET1_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),salivary gland development [GO:0007431] comp23534_c0_seq1,241,39.834,1.15741123,3,17,,3.00E-11,Q9Y5G0,Protocadherin gamma-B5 (PCDH-gamma-B5),Protocadherin gamma-B5 (PCDH-gamma-B5),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDGH_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp2353_c0_seq1,278,39.9281,0.58944425,4,0,,,,,,,,,,,2.00E-22,ruditapes_c24585,,,,,,, comp23563_c0_seq1,828,47.343,0.41625325,22,23,,2.00E-85,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,8.00E-118,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp23566_c0_seq1,224,49.1071,1.19168214,4,7,,7.00E-16,Q8LCP6,"Endoglucanase 10 (EC 3.2.1.4) (Endo-1,4-beta glucanase 10)","Endoglucanase 10 (EC 3.2.1.4) (Endo-1,4-beta glucanase 10)",GO:0008810; GO:0030245; GO:0005576; GO:0005886,cellulase activity; cellulose catabolic process; extracellular region; plasma membrane,PF00759;,,,,,,,,,GUN10_ARATH,Arabidopsis thaliana (Mouse-ear cress),cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555] comp23570_c0_seq1,207,42.9952,0.63674955,1,19,,,,,,,,,9.00E-34,CHOYP_RS27L.1.4,,,,,,,,, comp23618_c0_seq1,381,56.9554,0.84370272,1,21,,7.00E-42,P27903,DNA polymerase III subunit beta (EC 2.7.7.7),DNA polymerase III subunit beta (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0009360; GO:0006260; GO:0003887; GO:0005737,3'-5' exonuclease activity; DNA binding; DNA polymerase III complex; DNA replication; DNA-directed DNA polymerase activity; cytoplasm,PF00712;PF02767;PF02768;,,,,,,,,,DPO3B_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),DNA replication [GO:0006260] comp23620_c0_seq1,276,45.6522,0.42561378,2,3,,8.00E-10,Q3U5Q7,"UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Thymidylate kinase LPS-inducible member) (TYKi)","UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Thymidylate kinase LPS-inducible member) (TYKi)",GO:0005524; GO:0033862; GO:0071222; GO:0004127; GO:0005739; GO:0004550; GO:0009142; GO:0005634; GO:0006221,ATP binding; UMP kinase activity; cellular response to lipopolysaccharide; cytidylate kinase activity; mitochondrion; nucleoside diphosphate kinase activity; nucleoside triphosphate biosynthetic process; nucleus; pyrimidine nucleotide biosynthetic process,,,,,,,,,,CMPK2_MOUSE,Mus musculus (Mouse),cellular response to lipopolysaccharide [GO:0071222]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] comp23622_c0_seq1,218,44.0367,0.38170738,8,4,,6.00E-23,Q5BIM8,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC-8,GO:0031464; GO:0016363; GO:0000109; GO:0045739; GO:0043161; GO:0051865; GO:0043234; GO:0032403; GO:0000209; GO:0009411; GO:0006979; GO:0006283; GO:0004842,Cul4A-RING ubiquitin ligase complex; nuclear matrix; nucleotide-excision repair complex; positive regulation of DNA repair; proteasomal ubiquitin-dependent protein catabolic process; protein autoubiquitination; protein complex; protein complex binding; protein polyubiquitination; response to UV; response to oxidative stress; transcription-coupled nucleotide-excision repair; ubiquitin-protein ligase activity,PF00400;,5.00E-18,CHOYP_ERCC8.1.1,,,,,,,ERCC8_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283] comp23623_c0_seq1,268,44.7761,0.45034109,6,12,,3.00E-14,Q9BQ69,O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase),O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase),GO:0019213; GO:0016798; GO:0005739; GO:0005634; GO:0051725; GO:0042278; GO:0006974,"deacetylase activity; hydrolase activity, acting on glycosyl bonds; mitochondrion; nucleus; protein de-ADP-ribosylation; purine nucleoside metabolic process; response to DNA damage stimulus",PF01661;,,,,,,,,,MACD1_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] comp23636_c0_seq1,587,44.9744,0.43893323,19,21,,2.00E-13,Q5T011,Protein SZT2 (Seizure threshold 2 protein homolog),Protein SZT2 (Seizure threshold 2 protein homolog),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp23664_c0_seq1,201,47.7612,0.37408333,2,14,,7.00E-15,Q90405,Major vault protein (MVP100) (P100),Major vault protein (MVP100) (P100),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_DISOM,Diplobatis ommata (Ocellated electric ray) (Discopyge ommata), comp23665_c0_seq1,570,36.8421,0.81254401,11,19,,8.00E-08,Q99689,Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1),Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1),GO:0030424; GO:0007411; GO:0007155; GO:0071363; GO:0005813; GO:0005737; GO:0030425; GO:0051654; GO:0005874; GO:0015630; GO:0005886; GO:0045666; GO:0010976; GO:0006810,axon; axon guidance; cell adhesion; cellular response to growth factor stimulus; centrosome; cytoplasm; dendrite; establishment of mitochondrion localization; microtubule; microtubule cytoskeleton; plasma membrane; positive regulation of neuron differentiation; positive regulation of neuron projection development; transport,PF07763;,,,,,,,,,FEZ1_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to growth factor stimulus [GO:0071363]; establishment of mitochondrion localization [GO:0051654]; negative regulation of autophagosome assembly [GO:1902902]; nervous system development [GO:0007399]; positive regulation of neuron projection development [GO:0010976]; transport [GO:0006810] comp23675_c0_seq1,202,56.4356,1.20046515,0,19,,3.00E-37,Q6A997,Chaperone protein DnaJ 1,Chaperone protein DnaJ 1,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ1_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp23675_c1_seq1,237,62.0253,1.06331007,0,14,,3.00E-06,P67202,Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.193) (16S rRNA m3U1498 methyltransferase),,GO:0005737; GO:0008168; GO:0006364,cytoplasm; methyltransferase activity; rRNA processing,,,,,,,,,,RSME_MYCTU,, comp23696_c0_seq1,298,32.8859,0.37422199,10,9,,3.00E-07,Q96PE6,Zinc finger imprinted 3 (Zinc finger protein 657),Zinc finger imprinted 3 (Zinc finger protein 657),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZIM3_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp23707_c0_seq1,459,40.9586,0.43056247,13,9,,1.00E-12,Q61037,Tuberin (Tuberous sclerosis 2 protein homolog),Tuberin (Tuberous sclerosis 2 protein homolog),GO:0071889; GO:0005096; GO:0033596; GO:0030030; GO:0007507; GO:0048009; GO:0016020; GO:0032007; GO:0030178; GO:0008285; GO:0045792; GO:0014067; GO:0051898; GO:0006469; GO:0001843; GO:0005634; GO:0019902; GO:0014065; GO:0050918; GO:0006606; GO:0043491; GO:0051726; GO:0030100; GO:0046626; GO:0051056; GO:0001666,14-3-3 protein binding; GTPase activator activity; TSC1-TSC2 complex; cell projection organization; heart development; insulin-like growth factor receptor signaling pathway; membrane; negative regulation of TOR signaling cascade; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of protein kinase B signaling cascade; negative regulation of protein kinase activity; neural tube closure; nucleus; phosphatase binding; phosphatidylinositol 3-kinase cascade; positive chemotaxis; protein import into nucleus; protein kinase B signaling cascade; regulation of cell cycle; regulation of endocytosis; regulation of insulin receptor signaling pathway; regulation of small GTPase mediated signal transduction; response to hypoxia,PF11864;PF02145;PF03542;,3.00E-19,CHOYP_LOC101078033.1.1,,,,,,,TSC2_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; cellular response to insulin stimulus [GO:0032869]; glucose import [GO:0046323]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive chemotaxis [GO:0050918]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein transport into plasma membrane raft [GO:0044861]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to hypoxia [GO:0001666] comp23785_c0_seq1,783,42.2733,0.60955301,25,42,,,,,,,,,2.00E-29,CHOYP_CRE-UNC-89.1.3,,,,,,,,, comp23831_c0_seq1,209,66.5072,0.82954082,0,17,,1.00E-11,Q9SGA6,40S ribosomal protein S19-1,40S ribosomal protein S19-1,GO:0005618; GO:0022627; GO:0009506; GO:0003735; GO:0006412,cell wall; cytosolic small ribosomal subunit; plasmodesma; structural constituent of ribosome; translation,PF01090;,,,,,,,,,RS191_ARATH,Arabidopsis thaliana (Mouse-ear cress),ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] comp23851_c0_seq1,416,39.1827,0.56504392,5,23,,4.00E-53,Q9H1N7,Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (3'-phosphoadenosine 5'-phosphosulfate transporter) (PAPS transporter 2) (Solute carrier family 35 member B3),Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (3'-phosphoadenosine 5'-phosphosulfate transporter) (PAPS transporter 2) (Solute carrier family 35 member B3),GO:0050428; GO:0000139; GO:0005975; GO:0030203; GO:0016021; GO:0005739; GO:0055085; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; Golgi membrane; carbohydrate metabolic process; glycosaminoglycan metabolic process; integral to membrane; mitochondrion; transmembrane transport; xenobiotic metabolic process,PF08449;,,,,,,,,,S35B3_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp23866_c0_seq1,245,35.9184,0.77238335,10,5,,,,,,,,,2.00E-23,CHOYP_LOC100375266.1.1,,,,,,,,, comp23904_c0_seq1,261,43.295,0.24670795,5,11,,3.00E-16,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp23912_c0_seq1,310,38.7097,0.78097911,10,10,,5.00E-31,O46404,Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit gamma) (PI3-kinase subunit p85-gamma) (PtdIns-3-kinase regulatory subunit p85-gamma) (p55PIK),Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit gamma) (PI3-kinase subunit p85-gamma) (PtdIns-3-kinase regulatory subunit p85-gamma) (p55PIK),GO:0005942; GO:0035014; GO:0043551,phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity,PF16454;PF00017;,2.00E-25,CHOYP_LOC100372481.1.1,,,,,,,P55G_BOVIN,Bos taurus (Bovine),insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] comp23916_c0_seq2,355,42.5352,0.63937289,5,10,,4.00E-31,Q92887,Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2),Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2),GO:0005524; GO:0042626; GO:0016324; GO:0030644; GO:0006855; GO:0005887; GO:0046581; GO:0008514; GO:0015732; GO:0046685; GO:0009408; GO:0031427; GO:0006979; GO:0070327,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; apical plasma membrane; cellular chloride ion homeostasis; drug transmembrane transport; integral to plasma membrane; intercellular canaliculus; organic anion transmembrane transporter activity; prostaglandin transport; response to arsenic-containing substance; response to heat; response to methotrexate; response to oxidative stress; thyroid hormone transport",PF00664;PF00005;,,,,,,,,,MRP2_HUMAN,Homo sapiens (Human),cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp23919_c0_seq1,606,37.7888,0.64830814,22,28,,2.00E-37,Q80X82,Symplekin,Symplekin,GO:0007155; GO:0005737; GO:0005856; GO:0006378; GO:0005654; GO:0005886; GO:0035307; GO:0005923,cell adhesion; cytoplasm; cytoskeleton; mRNA polyadenylation; nucleoplasm; plasma membrane; positive regulation of protein dephosphorylation; tight junction,PF11935;PF12295;,5.00E-55,CHOYP_SYMPK.1.1,,,,,,,SYMPK_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; mRNA polyadenylation [GO:0006378]; positive regulation of protein dephosphorylation [GO:0035307] comp23922_c0_seq1,221,39.3665,0.23492544,12,0,,,,,,,,,2.00E-11,CHOYP_contig_046704,,,,,,,,, comp23930_c0_seq1,284,41.9014,0.69091766,11,12,,1.00E-47,Q5RDY7,Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5),Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5),GO:0004871,signal transducer activity,PF00400;,2.00E-51,CHOYP_LOC100368053.1.1,,,,,,,GBB5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of voltage-gated calcium channel activity [GO:1901386] comp23947_c0_seq1,329,43.769,0.25482861,2,16,,1.00E-24,Q8IWB9,Testis-expressed sequence 2 protein (Transmembrane protein 96),Testis-expressed sequence 2 protein (Transmembrane protein 96),GO:0016021; GO:0005543; GO:0007165; GO:0006665,integral to membrane; phospholipid binding; signal transduction; sphingolipid metabolic process,,,,,,,,,,TEX2_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665] comp23951_c0_seq1,380,44.7368,0.63359641,5,14,,1.00E-27,P43006,Excitatory amino acid transporter 2 (GLT-1) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2),Excitatory amino acid transporter 2 (GLT-1) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2),GO:0070779; GO:0051938; GO:0030534; GO:0030673; GO:0031668; GO:0015501; GO:0005887; GO:0035264; GO:0010259; GO:0046326; GO:0043200; GO:0042493; GO:0009611; GO:0017153; GO:0021537; GO:0007632,D-aspartate import; L-glutamate import; adult behavior; axolemma; cellular response to extracellular stimulus; glutamate:sodium symporter activity; integral to plasma membrane; multicellular organism growth; multicellular organismal aging; positive regulation of glucose import; response to amino acid stimulus; response to drug; response to wounding; sodium:dicarboxylate symporter activity; telencephalon development; visual behavior,PF00375;,,,,,,,,,EAA2_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; anion transmembrane transport [GO:0098656]; cellular response to extracellular stimulus [GO:0031668]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; positive regulation of glucose import [GO:0046326]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to light stimulus [GO:0009416]; response to wounding [GO:0009611]; telencephalon development [GO:0021537]; visual behavior [GO:0007632] comp23979_c0_seq1,243,51.0288,1.14619239,2,12,,6.00E-09,P24062,Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain],Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain],GO:0005524; GO:0007409; GO:0005901; GO:0030010; GO:0006955; GO:0051389; GO:0043559; GO:0043560; GO:0005520; GO:0005010; GO:0016021; GO:0043231; GO:0010656; GO:0043005; GO:0043548; GO:0048015; GO:0051054; GO:0045740; GO:0030335; GO:0032467; GO:0090031; GO:0046777; GO:0051291; GO:0051262; GO:0046328; GO:0033197,ATP binding; axonogenesis; caveola; establishment of cell polarity; immune response; inactivation of MAPKK activity; insulin binding; insulin receptor substrate binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; integral to membrane; intracellular membrane-bounded organelle; negative regulation of muscle cell apoptotic process; neuron projection; phosphatidylinositol 3-kinase binding; phosphatidylinositol-mediated signaling; positive regulation of DNA metabolic process; positive regulation of DNA replication; positive regulation of cell migration; positive regulation of cytokinesis; positive regulation of steroid hormone biosynthetic process; protein autophosphorylation; protein heterooligomerization; protein tetramerization; regulation of JNK cascade; response to vitamin E,PF00757;PF07714;PF01030;,,,,,,,,,IGF1R_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; axonogenesis [GO:0007409]; cellular response to aldosterone [GO:1904045]; cellular response to angiotensin [GO:1904385]; cellular response to estradiol stimulus [GO:0071392]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to testosterone stimulus [GO:0071394]; cellular senescence [GO:0090398]; cerebellum development [GO:0021549]; establishment of cell polarity [GO:0030010]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of muscle cell apoptotic process [GO:0010656]; neuron projection development [GO:0031175]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; protein autophosphorylation [GO:0046777]; protein heterooligomerization [GO:0051291]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328]; response to insulin [GO:0032868]; response to L-glutamate [GO:1902065]; response to vitamin E [GO:0033197] comp2397_c1_seq1,307,40.7166,0.64570916,3,3,,6.00E-11,Q0IHV1,Inverted formin-2,Inverted formin-2,GO:0030036,actin cytoskeleton organization,PF06367;PF06371;PF02181;PF02205;,,,,,,,,,INF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),actin cytoskeleton organization [GO:0030036] comp24051_c0_seq1,369,43.0894,0.23529585,8,19,,7.00E-30,Q68FJ9,Cysteine protease ATG4D (EC 3.4.22.-) (Autophagin-4) (Autophagy-related protein 4 homolog D),Cysteine protease ATG4D (EC 3.4.22.-) (Autophagin-4) (Autophagy-related protein 4 homolog D),GO:0006914; GO:0008234; GO:0005737; GO:0015031; GO:0006508,autophagy; cysteine-type peptidase activity; cytoplasm; protein transport; proteolysis,PF03416;,9.00E-18,CHOYP_ATG4D.1.1,,,,,,,ATG4D_XENLA,Xenopus laevis (African clawed frog),autophagy [GO:0006914]; protein transport [GO:0015031] comp24098_c0_seq1,248,40.7258,0.21030747,6,9,,1.00E-49,Q9DGD9,Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1),Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1),GO:0005524; GO:0007254; GO:0004707; GO:0048263,ATP binding; JNK cascade; MAP kinase activity; determination of dorsal identity,PF00069;,6.00E-43,CHOYP_JNK.1.1,4.00E-12,ruditapes_c22270,,,,,MK08_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),determination of dorsal identity [GO:0048263]; JNK cascade [GO:0007254]; rhythmic process [GO:0048511] comp24099_c0_seq1,217,48.8479,0.81102913,0,14,,2.00E-07,Q96L93,Kinesin-like protein KIF16B (Sorting nexin-23),Kinesin-like protein KIF16B (Sorting nexin-23),GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,,,,,,,,,KI16B_HUMAN,Homo sapiens (Human),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp24102_c0_seq1,250,46.4,0.59977065,4,11,,5.00E-29,Q5RA75,Protein FAM135A,Protein FAM135A,,,PF12394;PF05057;,1.00E-27,CHOYP_PHUM_PHUM293090.2.2,,,,,,,F135A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp24108_c0_seq1,213,43.1925,0.30866065,6,8,,6.00E-23,Q5QQ56,Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I),Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I),GO:0000139; GO:0008375; GO:0034605; GO:0030206; GO:0005789; GO:0015012; GO:0016021; GO:0030158,Golgi membrane; acetylglucosaminyltransferase activity; cellular response to heat; chondroitin sulfate biosynthetic process; endoplasmic reticulum membrane; heparan sulfate proteoglycan biosynthetic process; integral to membrane; protein xylosyltransferase activity,PF02485;PF12529;,6.00E-17,CHOYP_XYLT.2.2,,,,,,,XYLT1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),chondroitin sulfate biosynthetic process [GO:0030206]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] comp24118_c0_seq1,219,67.1233,1.43072474,0,11,,3.00E-15,Q8RM04,Acetone carboxylase beta subunit (EC 6.4.1.6),Acetone carboxylase beta subunit (EC 6.4.1.6),GO:0005524; GO:0018710; GO:0043443; GO:0016787,ATP binding; acetone carboxylase activity; acetone metabolic process; hydrolase activity,PF05378;PF01968;,,,,,,,,,ACXA_XANP2,Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2),acetone metabolic process [GO:0043443] comp24123_c0_seq1,316,46.8354,0.61114936,1,18,,5.00E-07,Q96PX9,Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B),Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,,,,,,,,,PKH4B_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp24143_c0_seq1,259,57.1429,1.32945736,0,14,,2.00E-51,Q6A6K7,DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta'),DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta'),GO:0003677; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF04997;PF00623;PF04983;PF05000;PF04998;,,,,,,,,,RPOC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"transcription, DNA-templated [GO:0006351]" comp24145_c0_seq1,224,48.6607,0.75810136,4,10,,,,,,,,,,,2.00E-15,ruditapes2_c1468,,,,,,, comp24165_c0_seq1,453,47.2406,0.47651767,2,0,,7.00E-11,Q91WP0,Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain],Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain],GO:0005509; GO:0006958; GO:0001867; GO:0005576; GO:0006508; GO:0004252,"calcium ion binding; complement activation, classical pathway; complement activation, lectin pathway; extracellular region; proteolysis; serine-type endopeptidase activity",PF00431;PF07645;PF00084;PF00089;,,,,,,,,,MASP2_MOUSE,Mus musculus (Mouse),"complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]" comp24165_c0_seq2,500,47.4,0.46389074,8,0,,7.00E-21,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp2419_c0_seq1,236,44.4915,0.68796591,8,0,,1.00E-11,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp24200_c0_seq2,356,66.573,1.09159277,1,25,,5.00E-20,O34971,Sensor protein KdpD (EC 2.7.13.3),Sensor protein KdpD (EC 2.7.13.3),GO:0005524; GO:0016021; GO:0018106; GO:0000155; GO:0005886; GO:0023014,ATP binding; integral to membrane; peptidyl-histidine phosphorylation; phosphorelay sensor kinase activity; plasma membrane; signal transduction by phosphorylation,PF13493;PF02518;PF02702;,,,,,,,,,KDPD_RATRA,Rathayibacter rathayi (Corynebacterium rathayi), comp24212_c0_seq1,249,38.1526,0.44366288,4,8,,,,,,,,,,,1.00E-11,ruditapes_c7836,,,,,,, comp24237_c0_seq1,323,42.4149,0.48399952,12,7,,2.00E-25,O94952,F-box only protein 21,F-box only protein 21,GO:0003677; GO:0000151; GO:0006511; GO:0004842,DNA binding; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF13369;PF08755;,3.00E-11,CHOYP_LOC100373758.1.1,,,,,,,FBX21_HUMAN,Homo sapiens (Human),ubiquitin-dependent protein catabolic process [GO:0006511] comp24249_c0_seq1,232,46.5517,0.65358858,0,12,,5.00E-07,Q8VHX6,Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),GO:0030018; GO:0003779; GO:0015629; GO:0030029; GO:0048747; GO:0042383,Z disc; actin binding; actin cytoskeleton; actin filament-based process; muscle fiber development; sarcolemma,PF00307;PF00630;,,,,,,,,,FLNC_MOUSE,Mus musculus (Mouse),actin filament-based process [GO:0030029]; muscle fiber development [GO:0048747] comp24260_c0_seq1,399,40.8521,0.54249889,10,11,,5.00E-21,P31396,Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0000977; GO:0004879; GO:0007552; GO:0016319; GO:0000122; GO:0005634; GO:0045944; GO:0040034; GO:0003707; GO:0004887; GO:0008270,"RNA polymerase II regulatory region sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metamorphosis; mushroom body development; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of development, heterochronic; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,,,,,,,,,HR3_DROME,Drosophila melanogaster (Fruit fly),"metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]" comp24262_c0_seq1,221,60.6335,1.14153913,1,1,,3.00E-11,P46547,Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),GO:0004177; GO:0005737; GO:0006508,aminopeptidase activity; cytoplasm; proteolysis,PF00561;,,,,,,,,,PIP_AERSO,Aeromonas sobria, comp24282_c0_seq1,323,41.4861,0.50625485,9,7,,1.00E-31,Q09499,Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0030969; GO:0004521; GO:0030176; GO:0002119; GO:0004674,ATP binding; UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response; endoribonuclease activity; integral to endoplasmic reticulum membrane; nematode larval development; protein serine/threonine kinase activity,PF00069;PF01011;PF06479;,1.00E-14,CHOYP_BRAFLDRAFT_118819.2.2,,,,,,,IRE1_CAEEL,Caenorhabditis elegans,endoplasmic reticulum unfolded protein response [GO:0030968]; mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response [GO:0030969]; nematode larval development [GO:0002119]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein phosphorylation [GO:0006468]; response to hypoxia [GO:0001666]; response to topologically incorrect protein [GO:0035966]; response to tunicamycin [GO:1904576] comp24289_c1_seq1,311,44.373,0.45911763,8,23,,1.00E-07,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp24306_c0_seq1,247,38.0567,0.402604,2,24,,2.00E-27,Q5I7G2,Retinoic acid receptor RXR (Retinoid X receptor) (LymRXR),Retinoic acid receptor RXR (Retinoid X receptor) (LymRXR),GO:0030424; GO:0005737; GO:0030426; GO:0016020; GO:0007275; GO:0005634; GO:0016918; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"axon; cytoplasm; growth cone; membrane; multicellular organismal development; nucleus; retinal binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF00105;,7.00E-17,CHOYP_RXR.1.2,,,,,,,RXR_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),"multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]" comp2430_c0_seq1,321,38.0062,0.8655998,10,2,,7.00E-11,Q9Y5I0,Protocadherin alpha-13 (PCDH-alpha-13),Protocadherin alpha-13 (PCDH-alpha-13),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF15974;,,,,,,,,,PCDAD_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp24317_c0_seq1,274,62.4088,1.09397891,0,30,,1.00E-18,P65336,4-alpha-glucanotransferase (EC 2.4.1.25) (Amylomaltase) (Disproportionating enzyme) (D-enzyme),,GO:0004134; GO:0005829,4-alpha-glucanotransferase activity; cytosol,,,,,,,,,,MALQ_MYCTU,, comp24329_c0_seq1,239,44.3515,0.6994658,0,7,,4.00E-06,O75901,Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor),Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor),GO:0005829; GO:0016197; GO:0005768; GO:0006605; GO:0007165; GO:0012510; GO:0005215,cytosol; endosomal transport; endosome; protein targeting; signal transduction; trans-Golgi network transport vesicle membrane; transporter activity,,,,,,,,,,RASF9_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; protein targeting [GO:0006605]; signal transduction [GO:0007165] comp24329_c0_seq2,270,44.4444,0.76641323,0,8,,,,,,,,,2.00E-23,CHOYP_LOC100373782.1.1,,,,,,,,, comp24336_c0_seq1,254,34.6457,0.65994812,2,24,,2.00E-25,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,,,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp24343_c0_seq1,353,39.3768,0.67816636,4,23,,4.00E-13,A5HNF6,Myeloid differentiation primary response protein MyD88,Myeloid differentiation primary response protein MyD88,GO:0002755; GO:0035419; GO:0005829; GO:0050830; GO:0016064; GO:0006954; GO:0045087; GO:0031663; GO:0044130; GO:0005634; GO:0005886; GO:0043123; GO:0046330; GO:0042346; GO:0051092; GO:0045080; GO:0032740; GO:0032747; GO:0032755; GO:0050671; GO:0032760; GO:0050727; GO:0002238; GO:0032494; GO:0009615; GO:0035681; GO:0034134; GO:0035682; GO:0034142; GO:0034146; GO:0034154; GO:0045351,MyD88-dependent toll-like receptor signaling pathway; activation of MAPK activity involved in innate immune response; cytosol; defense response to Gram-positive bacterium; immunoglobulin mediated immune response; inflammatory response; innate immune response; lipopolysaccharide-mediated signaling pathway; negative regulation of growth of symbiont in host; nucleus; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; positive regulation of NF-kappaB import into nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of chemokine biosynthetic process; positive regulation of interleukin-17 production; positive regulation of interleukin-23 production; positive regulation of interleukin-6 production; positive regulation of lymphocyte proliferation; positive regulation of tumor necrosis factor production; regulation of inflammatory response; response to molecule of fungal origin; response to peptidoglycan; response to virus; toll-like receptor 15 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 21 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 7 signaling pathway; type I interferon biosynthetic process,PF00531;PF13676;,,,,,,,,,MYD88_CHICK,Gallus gallus (Chicken),defense response to Gram-positive bacterium [GO:0050830]; establishment of endothelial intestinal barrier [GO:0090557]; immunoglobulin mediated immune response [GO:0016064]; induced systemic resistance [GO:0009682]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000338]; regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000341]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil migration [GO:1902622]; response to molecule of fungal origin [GO:0002238]; response to peptidoglycan [GO:0032494]; response to virus [GO:0009615]; type I interferon biosynthetic process [GO:0045351] comp24373_c0_seq1,216,35.1852,0.75348837,3,0,,6.00E-06,P53708,Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain],Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain],GO:0034678; GO:0045177; GO:0030030; GO:0016337; GO:0007160; GO:0045184; GO:0030198; GO:0042472; GO:0007229; GO:0007613; GO:0046872; GO:0001656; GO:0007399; GO:2000721; GO:0030511; GO:0048745,alpha8-beta1 integrin complex; apical part of cell; cell projection organization; cell-cell adhesion; cell-matrix adhesion; establishment of protein localization; extracellular matrix organization; inner ear morphogenesis; integrin-mediated signaling pathway; memory; metal ion binding; metanephros development; nervous system development; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; positive regulation of transforming growth factor beta receptor signaling pathway; smooth muscle tissue development,PF01839;PF00357;PF08441;,,,,,,,,,ITA8_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; metanephros development [GO:0001656]; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation [GO:2000721]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; single organismal cell-cell adhesion [GO:0016337]; smooth muscle tissue development [GO:0048745]; substrate adhesion-dependent cell spreading [GO:0034446] comp24374_c0_seq1,207,45.4106,0.37733307,0,17,,2.00E-18,Q58DD2,Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11),Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11),GO:0005794; GO:0008509; GO:0015301; GO:0005783; GO:0016021; GO:0005765; GO:0005886; GO:0008271; GO:0008272,Golgi apparatus; anion transmembrane transporter activity; anion:anion antiporter activity; endoplasmic reticulum; integral to membrane; lysosomal membrane; plasma membrane; secondary active sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S2611_BOVIN,Bos taurus (Bovine),bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sulfate transport [GO:0008272] comp24392_c0_seq1,833,46.0984,0.54155922,32,16,,1.00E-83,Q5RBR6,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,7.00E-43,CHOYP_SPRY3.1.1,,,,,,,SPRY3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp24393_c0_seq1,401,38.404,0.40930171,16,8,,,,,,,,,2.00E-27,CHOYP_BRAFLDRAFT_125022.1.1,,,,,,,,, comp24398_c0_seq1,608,42.2697,0.40570604,13,25,,2.00E-41,G3V7P1,Syntaxin-12 (Syntaxin-13),Syntaxin-12 (Syntaxin-13),GO:0031083; GO:0000139; GO:0005484; GO:0000149; GO:0031201; GO:0033344; GO:0010008; GO:0016021; GO:0006886; GO:0045121; GO:0045335; GO:0050821; GO:0016079,BLOC-1 complex; Golgi membrane; SNAP receptor activity; SNARE binding; SNARE complex; cholesterol efflux; endosome membrane; integral to membrane; intracellular protein transport; membrane raft; phagocytic vesicle; protein stabilization; synaptic vesicle exocytosis,PF05739;,9.00E-27,CHOYP_BRAFLDRAFT_59863.1.1,,,,,,,STX12_RAT,Rattus norvegicus (Rat),intracellular protein transport [GO:0006886]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] comp24425_c0_seq1,409,45.7213,0.19289694,10,14,,5.00E-26,Q14728,Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein),Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein),GO:0006915; GO:0016021; GO:0008493; GO:0055085,apoptotic process; integral to membrane; tetracycline transporter activity; transmembrane transport,PF07690;,5.00E-34,CHOYP_NEMVEDRAFT_V1G177762.1.1,,,,,,,MFS10_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; sodium-independent organic anion transport [GO:0043252]; transport [GO:0006810] comp24433_c0_seq1,848,48.9387,0.49303204,32,20,,3.00E-75,Q86X10,Ral GTPase-activating protein subunit beta (p170),Ral GTPase-activating protein subunit beta (p170),GO:0017123; GO:0032484; GO:0032859; GO:0046982; GO:0060178,Ral GTPase activator activity; Ral protein signal transduction; activation of Ral GTPase activity; protein heterodimerization activity; regulation of exocyst localization,,3.00E-48,CHOYP_BRAFLDRAFT_116449.1.1,,,,,,,RLGPB_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] comp24447_c0_seq1,250,47.2,0.64914832,3,9,,7.00E-30,A0JPE9,Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5),Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5),GO:0005524; GO:0019563; GO:0004370,ATP binding; glycerol catabolic process; glycerol kinase activity,PF02782;PF00370;,,,,,,,,,GLPK5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glycerol catabolic process [GO:0019563]; phosphorylation [GO:0016310] comp24448_c0_seq1,253,47.0356,0.28798636,8,8,,,,,,,,,1.00E-20,CHOYP_BRAFLDRAFT_120904.1.1,,,,,,,,, comp24477_c0_seq1,394,46.1929,0.81099556,2,21,,4.00E-16,P40792,Ras-related protein Rac1,Ras-related protein Rac1,GO:0005525; GO:0003924; GO:0007254; GO:0051017; GO:0034334; GO:0048675; GO:0007413; GO:0007298; GO:0035212; GO:0030866; GO:0005829; GO:0048813; GO:0071907; GO:0046843; GO:0046664; GO:0007394; GO:0048615; GO:0042067; GO:0019897; GO:0007390; GO:0008347; GO:0008258; GO:0007516; GO:0035099; GO:0035320; GO:0002433; GO:0030032; GO:0035011; GO:0008078; GO:0007017; GO:0016335; GO:0008045; GO:0048747; GO:0007520; GO:0051450; GO:0010593; GO:0007422; GO:0051491; GO:0071902; GO:0050770; GO:0051726; GO:0048814; GO:0045610; GO:0051963; GO:0006974; GO:0016028; GO:0042052; GO:0007435; GO:0050975; GO:0007264; GO:0007426; GO:0007419,"GTP binding; GTPase activity; JNK cascade; actin filament bundle assembly; adherens junction maintenance; axon extension; axonal fasciculation; border follicle cell migration; cell competition in a multicellular organism; cortical actin cytoskeleton organization; cytosol; dendrite morphogenesis; determination of digestive tract left/right asymmetry; dorsal appendage formation; dorsal closure, amnioserosa morphology change; dorsal closure, elongation of leading edge cells; embryonic anterior midgut (ectodermal) morphogenesis; establishment of ommatidial planar polarity; extrinsic to plasma membrane; germ-band shortening; glial cell migration; head involution; hemocyte development; hemocyte migration; imaginal disc-derived wing hair site selection; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; lamellipodium assembly; melanotic encapsulation of foreign target; mesodermal cell migration; microtubule-based process; morphogenesis of larval imaginal disc epithelium; motor neuron axon guidance; muscle fiber development; myoblast fusion; myoblast proliferation; negative regulation of lamellipodium assembly; peripheral nervous system development; positive regulation of filopodium assembly; positive regulation of protein serine/threonine kinase activity; regulation of axonogenesis; regulation of cell cycle; regulation of dendrite morphogenesis; regulation of hemocyte differentiation; regulation of synapse assembly; response to DNA damage stimulus; rhabdomere; rhabdomere development; salivary gland morphogenesis; sensory perception of touch; small GTPase mediated signal transduction; tracheal outgrowth, open tracheal system; ventral cord development",PF00071;,,,,,,,,,RAC1_DROME,Drosophila melanogaster (Fruit fly),"actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; adherens junction maintenance [GO:0034334]; axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; border follicle cell migration [GO:0007298]; cell-cell junction organization [GO:0045216]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cortical actin cytoskeleton organization [GO:0030866]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; establishment of ommatidial planar polarity [GO:0042067]; establishment of tissue polarity [GO:0007164]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; mesodermal cell migration [GO:0008078]; microtubule-based process [GO:0007017]; morphogenesis of larval imaginal disc epithelium [GO:0016335]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle fiber development [GO:0048747]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of axonogenesis [GO:0050770]; regulation of cell cycle [GO:0051726]; regulation of dendrite morphogenesis [GO:0048814]; regulation of hemocyte differentiation [GO:0045610]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; ventral cord development [GO:0007419]" comp24487_c1_seq1,213,47.4178,0.52624111,0,4,,2.00E-15,Q6P0C6,Lipoma HMGIC fusion partner-like 2 protein,Lipoma HMGIC fusion partner-like 2 protein,GO:0016021,integral to membrane,PF10242;,1.00E-13,CHOYP_BRAFLDRAFT_92907.1.2,,,,,,,LHPL2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp24499_c0_seq1,771,44.2283,0.56586483,30,7,,6.00E-67,Q96FN5,Kinesin-like protein KIF12,Kinesin-like protein KIF12,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,5.00E-101,CHOYP_LOC100902075.1.1,,,,,,,KIF12_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp24510_c0_seq1,387,39.0181,0.34581336,6,14,,1.00E-17,Q60HF6,Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase),GO:0004565; GO:0005975; GO:0005764,beta-galactosidase activity; carbohydrate metabolic process; lysosome,PF13364;PF01301;,,,,,,,,,BGAL_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),carbohydrate metabolic process [GO:0005975] comp24523_c0_seq1,391,44.2455,0.53333682,6,24,,,,,,,,,6.00E-14,CHOYP_PDZRN3.1.1,,,,,,,,, comp24537_c0_seq1,217,33.1797,0.34063223,5,10,,3.00E-07,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp24550_c0_seq1,681,38.326,0.8857162,24,17,,1.00E-52,Q5WA50,Cephalotocin receptor 2,Cephalotocin receptor 2,GO:0016021; GO:0005886; GO:0046887; GO:0016500; GO:0005000,integral to membrane; plasma membrane; positive regulation of hormone secretion; protein-hormone receptor activity; vasopressin receptor activity,PF00001;,,,,,,,,,CTR2_OCTVU,Octopus vulgaris (Common octopus),G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of hormone secretion [GO:0046887] comp24566_c0_seq1,363,36.9146,0.73044033,0,24,,5.00E-35,Q17LW0,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,9.00E-56,CHOYP_MYO7A.1.3,,,,,,,MYO7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp24587_c0_seq1,328,37.8049,0.42973231,6,17,,4.00E-09,E7FDE0,Transmembrane protein 138,Transmembrane protein 138,GO:0005929; GO:0042384; GO:0016021; GO:0005774,cilium; cilium assembly; integral to membrane; vacuolar membrane,PF14935;,6.00E-26,CHOYP_BRAFLDRAFT_277366.1.1,,,,,,,TM138_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384] comp24671_c0_seq1,309,44.0129,0.29087802,6,8,,2.00E-30,Q5XPI4,E3 ubiquitin-protein ligase RNF123 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123),E3 ubiquitin-protein ligase RNF123 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123),GO:0005737; GO:0016874; GO:0016567; GO:0008270,cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,PF00622;,7.00E-25,CHOYP_RN123.1.2,,,,,,,RN123_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp24676_c0_seq1,300,41.3333,0.70547659,9,8,,2.00E-27,Q9R1X5,Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP),Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP),GO:0005524; GO:0006200; GO:0042626; GO:0016021,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane",PF00664;PF00005;,2.00E-30,CHOYP_MRP5.1.3,,,,,,,MRP5_MOUSE,Mus musculus (Mouse), comp24705_c0_seq1,875,44.6857,0.58826766,56,0,,1.00E-114,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-144,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp24724_c0_seq1,459,57.2985,0.80139753,1,31,,2.00E-12,P94408,Uncharacterized transporter YclF,Uncharacterized transporter YclF,GO:0016021; GO:0006857; GO:0015197; GO:0005886,integral to membrane; oligopeptide transport; peptide transporter activity; plasma membrane,PF00854;,,,,,,,,,YCLF_BACSU,Bacillus subtilis (strain 168),oligopeptide transport [GO:0006857] comp24725_c0_seq1,207,59.4203,1.20466132,0,13,,1.00E-10,Q55752,RlpA-like protein,RlpA-like protein,,,PF03330;,,,,,,,,,RLPA_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa), comp24750_c0_seq1,347,43.5159,0.48842511,9,11,,,,,,,,,2.00E-31,CHOYP_NEMVEDRAFT_V1G240929.1.1,,,,,,,,, comp2475_c0_seq1,314,42.6752,0.44025604,11,1,,4.00E-14,Q8R512,UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5),UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5),GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF08059;PF00789;,1.00E-15,CHOYP_LOC100185765.2.2,,,,,,,UBX11_RAT,Rattus norvegicus (Rat),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp24765_c0_seq1,214,49.5327,0.91882348,2,3,,1.00E-21,A3KG59,Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),GO:0016787,hydrolase activity,PF07687;PF01546;,5.00E-12,CHOYP_P20D2.1.2,,,,,,,P20D2_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268] comp24783_c0_seq1,454,44.9339,0.49653019,16,7,,3.00E-11,Q96QT4,Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7),Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7),GO:0005524; GO:0031032; GO:0005262; GO:0016340; GO:0008219; GO:0016021; GO:0046872; GO:0005886; GO:0046777; GO:0004674; GO:0001726,ATP binding; actomyosin structure organization; calcium channel activity; calcium-dependent cell-matrix adhesion; cell death; integral to membrane; metal ion binding; plasma membrane; protein autophosphorylation; protein serine/threonine kinase activity; ruffle,PF02816;PF00520;PF16519;,,,,,,,,,TRPM7_HUMAN,Homo sapiens (Human),actomyosin structure organization [GO:0031032]; calcium-dependent cell-matrix adhesion [GO:0016340]; calcium ion transmembrane transport [GO:0070588]; cellular magnesium ion homeostasis [GO:0010961]; necroptotic process [GO:0070266]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262] comp24814_c0_seq1,334,41.6168,0.41980326,7,20,,4.00E-31,Q32NT4,Leucine-rich repeat-containing protein 58,Leucine-rich repeat-containing protein 58,,,PF13855;,7.00E-25,CHOYP_LOC100376973.1.1,,,,,,,LRC58_XENLA,Xenopus laevis (African clawed frog), comp2484_c0_seq1,239,46.8619,0.84861659,1,5,,1.00E-16,B0JZG0,Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2),Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2),GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF00860;,2.00E-17,CHOYP_BRAFLDRAFT_90196.2.2,,,,,,,S23A2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp24876_c0_seq1,289,50.173,0.66463745,9,5,,4.00E-43,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,4.00E-46,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp24943_c0_seq1,243,42.3868,0.55204555,4,10,,1.00E-07,Q22306,UPF0046 protein T07D4.2,UPF0046 protein T07D4.2,GO:0016787,hydrolase activity,PF00149;,,,,,,,,,YW12_CAEEL,Caenorhabditis elegans, comp24947_c0_seq1,282,43.9716,0.58897723,1,26,,4.00E-20,O42222,Growth/differentiation factor 8 (GDF-8) (Myostatin) (Myostatin-1) (zfMSTN-1) (Myostatin-B),Growth/differentiation factor 8 (GDF-8) (Myostatin) (Myostatin-1) (zfMSTN-1) (Myostatin-B),GO:0005576; GO:0005615; GO:0040007; GO:0008083; GO:0045967; GO:0045843; GO:0007519; GO:0007179,extracellular region; extracellular space; growth; growth factor activity; negative regulation of growth rate; negative regulation of striated muscle tissue development; skeletal muscle tissue development; transforming growth factor beta receptor signaling pathway,PF00019;PF00688;,,,,,,,,,GDF8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell development [GO:0048468]; growth [GO:0040007]; muscle organ development [GO:0007517]; negative regulation of growth [GO:0045926]; negative regulation of growth rate [GO:0045967]; negative regulation of striated muscle tissue development [GO:0045843]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal muscle tissue development [GO:0007519]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp24958_c0_seq1,217,39.1705,0.85444144,1,33,,5.00E-26,Q5U316,Ras-related protein Rab-35,Ras-related protein Rab-35,GO:0019003; GO:0005525; GO:0031253; GO:1990090; GO:0045334; GO:0005905; GO:0000910; GO:0016197; GO:0010008; GO:0045171; GO:0042470; GO:0005739; GO:0031175; GO:0005546; GO:0036010; GO:0015031; GO:0007264,"GDP binding; GTP binding; cell projection membrane; cellular response to nerve growth factor stimulus; clathrin-coated endocytic vesicle; coated pit; cytokinesis; endosomal transport; endosome membrane; intercellular bridge; melanosome; mitochondrion; neuron projection development; phosphatidylinositol-4,5-bisphosphate binding; protein localization to endosome; protein transport; small GTPase mediated signal transduction",PF00071;,7.00E-29,CHOYP_RAB35.1.1,,,,,,,RAB35_RAT,Rattus norvegicus (Rat),antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp24989_c0_seq1,516,41.0853,0.64561834,25,9,,5.00E-49,Q5RDU4,Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17),Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17),GO:0003950,NAD+ ADP-ribosyltransferase activity,PF00644;,6.00E-35,CHOYP_PARP8.1.1,,,,,,,PARP6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp25019_c0_seq1,202,33.6634,1.07694947,9,0,,,,,,,,,,,7.00E-14,ruditapes_c5444,,,,,,, comp25034_c0_seq1,237,64.557,0.89936332,0,12,,6.00E-13,Q15UY7,Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-),Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016021; GO:0034040; GO:0005886,ATP binding; ATP catabolic process; integral to membrane; lipid-transporting ATPase activity; plasma membrane,PF00664;PF00005;,,,,,,,,,MSBA_PSEA6,Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087), comp25042_c0_seq1,374,47.5936,0.58049951,12,10,,1.00E-13,Q6GMK6,Tetraspanin-9 (Tspan-9),Tetraspanin-9 (Tspan-9),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166] comp25044_c0_seq1,331,45.3172,0.47352901,0,0,,7.00E-12,Q5Y5T2,Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 18) (DHHC-18),Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 18) (DHHC-18),GO:0034613; GO:0016021; GO:0016409; GO:0008270,cellular protein localization; integral to membrane; palmitoyltransferase activity; zinc ion binding,PF01529;,,,,,,,,,ZDH18_MOUSE,Mus musculus (Mouse),cellular protein localization [GO:0034613]; protein palmitoylation [GO:0018345] comp25044_c0_seq2,582,40.2062,0.29952382,12,14,,3.00E-14,Q5B3W7,Palmitoyltransferase erf2 (EC 2.3.1.225) (DHHC cysteine-rich domain-containing protein erf2) (Ras protein acyltransferase),Palmitoyltransferase erf2 (EC 2.3.1.225) (DHHC cysteine-rich domain-containing protein erf2) (Ras protein acyltransferase),GO:0005789; GO:0016021; GO:0016746; GO:0008270,"endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ERFB_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans), comp25047_c0_seq1,330,44.8485,0.60846147,5,24,,2.00E-24,P50429,Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S),GO:0005794; GO:0003943; GO:0004065; GO:0006914; GO:0007417; GO:0005764; GO:0046872; GO:0005739; GO:0043627; GO:0051597; GO:0007584; GO:0009268; GO:0005791,Golgi apparatus; N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; autophagy; central nervous system development; lysosome; metal ion binding; mitochondrion; response to estrogen stimulus; response to methylmercury; response to nutrient; response to pH; rough endoplasmic reticulum,PF00884;,2.00E-26,CHOYP_LOC584392.1.1,,,,,,,ARSB_MOUSE,Mus musculus (Mouse),colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632] comp25056_c0_seq1,571,45.1839,0.58448217,21,19,,2.00E-28,Q80Z37,E3 ubiquitin-protein ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3),E3 ubiquitin-protein ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3),GO:0003677; GO:0016605; GO:0019789; GO:0003823; GO:0005814; GO:0036064; GO:0000930; GO:0042771; GO:0051457; GO:0016607; GO:0032391; GO:0045893; GO:0051443; GO:0043161; GO:0070936; GO:0034504; GO:0006513; GO:0016925; GO:0042127; GO:0000922; GO:0004842; GO:0008270,"DNA binding; PML body; SUMO ligase activity; antigen binding; centriole; cilium basal body; gamma-tubulin complex; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; maintenance of protein location in nucleus; nuclear speck; photoreceptor connecting cilium; positive regulation of transcription, DNA-dependent; positive regulation of ubiquitin-protein ligase activity; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein localization to nucleus; protein monoubiquitination; protein sumoylation; regulation of cell proliferation; spindle pole; ubiquitin-protein ligase activity; zinc ion binding",,1.00E-18,CHOYP_LOC576802.1.1,,,,,,,TOPRS_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein localization to nucleus [GO:0034504]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of cell proliferation [GO:0042127]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp25125_c0_seq1,211,46.9194,0.3624013,16,14,,3.00E-08,O61309,Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS),Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS),GO:0010181; GO:0050661; GO:0050660; GO:0020037; GO:0005506; GO:0006809; GO:0004517,FMN binding; NADP binding; flavin adenine dinucleotide binding; heme binding; iron ion binding; nitric oxide biosynthetic process; nitric-oxide synthase activity,PF00667;PF00258;PF00175;PF02898;,,,,,,,,,NOS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),nitric oxide biosynthetic process [GO:0006809] comp25133_c0_seq1,358,46.9274,1.0228,4,10,,3.00E-20,P70579,Metabotropic glutamate receptor 8 (mGluR8),Metabotropic glutamate receptor 8 (mGluR8),GO:0050966; GO:0001642; GO:0005887; GO:0043005; GO:0043025; GO:0045211; GO:0042734; GO:1901214; GO:0046928; GO:0007608; GO:0035249,"detection of mechanical stimulus involved in sensory perception of pain; group III metabotropic glutamate receptor activity; integral to plasma membrane; neuron projection; neuronal cell body; postsynaptic membrane; presynaptic membrane; regulation of neuron death; regulation of neurotransmitter secretion; sensory perception of smell; synaptic transmission, glutamatergic",PF00003;PF01094;PF07562;,,,,,,,,,GRM8_RAT,Rattus norvegicus (Rat),"adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; regulation of neuron death [GO:1901214]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; sensory perception of smell [GO:0007608]; synaptic transmission, glutamatergic [GO:0035249]" comp25150_c0_seq1,229,51.5284,0.72702536,0,15,,1.00E-33,Q3ZC26,Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11),Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11),GO:0006915; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apoptotic process; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF00474;,8.00E-35,CHOYP_SC5A9.3.5,,,,,,,SC5AB_BOVIN,Bos taurus (Bovine),apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp25220_c0_seq1,245,39.5918,0.75527574,7,9,,3.00E-24,P0C091,FRAS1-related extracellular matrix protein 3,FRAS1-related extracellular matrix protein 3,GO:0005604; GO:0007155; GO:0007154; GO:0016021; GO:0046872,basement membrane; cell adhesion; cell communication; integral to membrane; metal ion binding,PF03160;,,,,,,,,,FREM3_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154] comp25234_c0_seq1,528,44.3182,0.75007732,3,52,,6.00E-24,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp25235_c0_seq1,322,32.2981,0.36704899,7,13,,1.00E-10,Q9VYF2,Putative inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3),Putative inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3),GO:0005737; GO:0006021; GO:0008934; GO:0052832; GO:0052833; GO:0016021; GO:0046872; GO:0006661; GO:0046854; GO:0007165,cytoplasm; inositol biosynthetic process; inositol monophosphate 1-phosphatase activity; inositol monophosphate 3-phosphatase activity; inositol monophosphate 4-phosphatase activity; integral to membrane; metal ion binding; phosphatidylinositol biosynthetic process; phosphatidylinositol phosphorylation; signal transduction,PF00459;,9.00E-11,CHOYP_BRAFLDRAFT_119617.1.1,,,,,,,IMPA3_DROME,Drosophila melanogaster (Fruit fly),dephosphorylation [GO:0016311]; inositol biosynthetic process [GO:0006021]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165] comp25242_c0_seq1,201,60.6965,0.97744355,0,21,,2.00E-14,Q82JT9,Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III),Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III),GO:0005737; GO:0006397; GO:0046872; GO:0090305; GO:0019843; GO:0016075; GO:0006364; GO:0004525; GO:0008033,cytoplasm; mRNA processing; metal ion binding; nucleic acid phosphodiester bond hydrolysis; rRNA binding; rRNA catabolic process; rRNA processing; ribonuclease III activity; tRNA processing,PF00035;PF14622;,,,,,,,,,RNC_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),mRNA processing [GO:0006397]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033] comp25254_c0_seq1,325,46.4615,0.24895234,19,0,,2.00E-42,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,4.00E-41,CHOYP_EMAL6.1.1,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp25259_c0_seq1,350,45.7143,0.43882215,7,12,,1.00E-45,O14976,Cyclin-G-associated kinase (EC 2.7.11.1),Cyclin-G-associated kinase (EC 2.7.11.1),GO:0005524; GO:0005794; GO:0007049; GO:0005925; GO:0048471; GO:0004674,ATP binding; Golgi apparatus; cell cycle; focal adhesion; perinuclear region of cytoplasm; protein serine/threonine kinase activity,PF00069;PF10409;,,,,,,,,,GAK_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; establishment of protein localization to Golgi [GO:0072600]; establishment of protein localization to plasma membrane [GO:0090002]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; negative regulation of neuron projection development [GO:0010977]; receptor-mediated endocytosis [GO:0006898] comp25273_c0_seq1,261,47.1264,0.4156592,4,15,,,,,,,,,4.00E-14,CHOYP_contig_007749,,,,,,,,, comp25296_c0_seq1,334,44.3114,0.55068987,3,19,,1.00E-27,Q13884,Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43),Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43),GO:0030054; GO:0005737; GO:0005856; GO:0016010; GO:0006936; GO:0005543; GO:0042383; GO:0045202,cell junction; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; muscle contraction; phospholipid binding; sarcolemma; synapse,PF00595;PF00169;,8.00E-18,CHOYP_LOC592864.1.1,,,,,,,SNTB1_HUMAN,Homo sapiens (Human),muscle contraction [GO:0006936] comp25307_c0_seq1,390,46.6667,0.5617853,8,17,,3.00E-54,P53356,Tyrosine-protein kinase HTK16 (EC 2.7.10.2),Tyrosine-protein kinase HTK16 (EC 2.7.10.2),GO:0005524; GO:0004715; GO:0018108,ATP binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF12796;PF07714;PF00017;,3.00E-55,CHOYP_LOC100118048.1.1,,,,,,,HTK16_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata), comp25327_c0_seq1,247,43.3198,0.88890346,17,3,,9.00E-06,Q96CW5,Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98),Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98),GO:0000086; GO:0005814; GO:0005829; GO:0043015; GO:0007020; GO:0005827; GO:0007338; GO:0005200,G2/M transition of mitotic cell cycle; centriole; cytosol; gamma-tubulin binding; microtubule nucleation; polar microtubule; single fertilization; structural constituent of cytoskeleton,PF04130;,,,,,,,,,GCP3_HUMAN,Homo sapiens (Human),centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; single fertilization [GO:0007338] comp25337_c0_seq1,321,52.9595,0.80233337,4,12,,4.00E-06,Q09YL6,Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5),Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5),,,PF00536;,,,,,,,,,SAMD5_BOVIN,Bos taurus (Bovine), comp25352_c0_seq1,578,45.6747,0.31900922,26,31,,2.00E-84,Q9Y6R4,Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),GO:0005524; GO:0007254; GO:0004709; GO:0060718; GO:0005737; GO:0019100; GO:0046872; GO:0048471; GO:0001890; GO:0043507; GO:0010468,ATP binding; JNK cascade; MAP kinase kinase kinase activity; chorionic trophoblast cell differentiation; cytoplasm; male germ-line sex determination; metal ion binding; perinuclear region of cytoplasm; placenta development; positive regulation of JUN kinase activity; regulation of gene expression,PF00069;,3.00E-46,CHOYP_LOC101174856.1.1,,,,,,,M3K4_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] comp25360_c0_seq1,229,45.4148,0.42593405,4,12,,9.00E-06,Q6DG19,Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),GO:0016021; GO:0006810,integral to membrane; transport,PF05631;,7.00E-17,CHOYP_LOC100181613.1.1,,,,,,,MFSD5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp25378_c0_seq1,240,42.9167,0.27262917,8,9,,2.00E-06,B2RXS4,Plexin-B2,Plexin-B2,GO:0007420; GO:0005887; GO:0005622; GO:0001843; GO:0007405; GO:0050772; GO:0032319; GO:0008360; GO:2001222; GO:0001932; GO:0017154,brain development; integral to plasma membrane; intracellular; neural tube closure; neuroblast proliferation; positive regulation of axonogenesis; regulation of Rho GTPase activity; regulation of cell shape; regulation of neuron migration; regulation of protein phosphorylation; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB2_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp25403_c0_seq1,355,65.9155,1.17106192,0,24,,4.00E-13,O67610,3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),GO:0004316; GO:0051287; GO:0050661; GO:0030497,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NAD binding; NADP binding; fatty acid elongation,,,,,,,,,,FABG_AQUAE,Aquifex aeolicus (strain VF5),fatty acid elongation [GO:0030497] comp25406_c0_seq1,312,48.3974,0.94278077,0,21,,2.00E-12,P13611,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),GO:0005796; GO:0005509; GO:0030246; GO:0005975; GO:0007155; GO:0008037; GO:0030206; GO:0030207; GO:0030208; GO:0030198; GO:0005615; GO:0008347; GO:0007507; GO:0005540; GO:0043202; GO:0007275; GO:0005578,Golgi lumen; calcium ion binding; carbohydrate binding; carbohydrate metabolic process; cell adhesion; cell recognition; chondroitin sulfate biosynthetic process; chondroitin sulfate catabolic process; dermatan sulfate biosynthetic process; extracellular matrix organization; extracellular space; glial cell migration; heart development; hyaluronic acid binding; lysosomal lumen; multicellular organismal development; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell recognition [GO:0008037]; central nervous system development [GO:0007417]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate biosynthetic process [GO:0030208]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; glycosaminoglycan metabolic process [GO:0030203]; multicellular organism development [GO:0007275]; osteoblast differentiation [GO:0001649]; skeletal system development [GO:0001501] comp25420_c0_seq1,230,44.3478,0.44681696,3,14,,4.00E-17,P51799,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,,,,,,,,,CLCN7_RAT,Rattus norvegicus (Rat),response to pH [GO:0009268] comp25443_c0_seq1,390,36.4103,0.48153026,4,16,,3.00E-14,Q54PP7,BEACH domain-containing protein lvsF,BEACH domain-containing protein lvsF,,,PF02138;PF14844;PF00400;,,,,,,,,,LVSF_DICDI,Dictyostelium discoideum (Slime mold), comp25471_c0_seq1,210,41.9048,0.4416636,4,9,,4.00E-08,Q3UYG8,O-acetyl-ADP-ribose deacetylase MACROD2 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 2) ([Protein ADP-ribosylglutamate] hydrolase),O-acetyl-ADP-ribose deacetylase MACROD2 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 2) ([Protein ADP-ribosylglutamate] hydrolase),GO:0007420; GO:0016798; GO:0005634; GO:0051725; GO:0006974,"brain development; hydrolase activity, acting on glycosyl bonds; nucleus; protein de-ADP-ribosylation; response to DNA damage stimulus",PF01661;,,,,,,,,,MACD2_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] comp25483_c0_seq1,274,42.3358,0.98215594,2,9,,2.00E-13,Q9BST9,Rhotekin,Rhotekin,GO:0005525; GO:0017049; GO:0005095; GO:0007266; GO:0006915; GO:0005543,GTP binding; GTP-Rho binding; GTPase inhibitor activity; Rho protein signal transduction; apoptotic process; phospholipid binding,PF08174;PF00169;,2.00E-18,CHOYP_LOC581809.1.2,,,,,,,RTKN_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165] comp25483_c0_seq2,229,48.0349,0.84645308,3,0,,2.00E-19,Q6V7V2,Rhotekin,Rhotekin,GO:0005525; GO:0017049; GO:0005095; GO:0007266; GO:0006915; GO:0005543,GTP binding; GTP-Rho binding; GTPase inhibitor activity; Rho protein signal transduction; apoptotic process; phospholipid binding,PF08174;,5.00E-25,CHOYP_LOC581809.2.2,,,,,,,RTKN_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; Rho protein signal transduction [GO:0007266] comp2548_c0_seq1,294,43.1973,0.95399114,9,0,,1.00E-11,P23642,Mannan polymerase I complex VAN1 subunit (M-pol I subunit VAN1) (Vanadate resistance protein),Mannan polymerase I complex VAN1 subunit (M-pol I subunit VAN1) (Vanadate resistance protein),GO:0000009; GO:0000136; GO:0000032; GO:0005789; GO:0006487; GO:0040008; GO:0030435,"alpha-1,6-mannosyltransferase activity; alpha-1,6-mannosyltransferase complex; cell wall mannoprotein biosynthetic process; endoplasmic reticulum membrane; protein N-linked glycosylation; regulation of growth; sporulation resulting in formation of a cellular spore",,,,,,,,,,VAN1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cell wall mannoprotein biosynthetic process [GO:0000032]; protein N-linked glycosylation [GO:0006487]; regulation of growth [GO:0040008]; sporulation resulting in formation of a cellular spore [GO:0030435] comp25497_c0_seq1,295,44.0678,0.6458256,7,9,,7.00E-10,Q7UC29,Sulfate/thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) (Sulfate-transporting ATPase),Sulfate/thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) (Sulfate-transporting ATPase),GO:0005524; GO:0006200; GO:0005886; GO:0015419; GO:0008272,ATP binding; ATP catabolic process; plasma membrane; sulfate transmembrane-transporting ATPase activity; sulfate transport,PF00005;PF12857;,,,,,,,,,CYSA_SHIFL,Shigella flexneri, comp25505_c0_seq1,204,39.2157,0.67480226,2,7,,1.00E-09,P02707,Hepatic lectin,Hepatic lectin,GO:0030246; GO:0006897; GO:0016021,carbohydrate binding; endocytosis; integral to membrane,PF00059;,,,,,,,,,LECH_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp25508_c0_seq1,349,43.553,0.36363935,3,15,,2.00E-08,Q9FT51,ABC transporter G family member 27 (ABC transporter ABCG.27) (AtABCG27) (Probable white-brown complex homolog protein 28) (AtWBC28),ABC transporter G family member 27 (ABC transporter ABCG.27) (AtABCG27) (Probable white-brown complex homolog protein 28) (AtWBC28),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport,PF01061;PF00005;,4.00E-22,CHOYP_LOC100166121.1.1,,,,,,,AB27G_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp25531_c0_seq1,234,40.5983,1.0472562,0,17,,2.00E-09,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,1.00E-14,CHOYP_LOC100372773.9.9,4.00E-17,ruditapes_c15288,,,,,HS12B_HUMAN,Homo sapiens (Human), comp25570_c0_seq1,224,49.1071,1.04272187,5,8,,5.00E-15,P54793,Arylsulfatase F (ASF) (EC 3.1.6.-),Arylsulfatase F (ASF) (EC 3.1.6.-),GO:0004065; GO:0005788; GO:0005576; GO:0006687; GO:0046872; GO:0043687; GO:0044281,arylsulfatase activity; endoplasmic reticulum lumen; extracellular region; glycosphingolipid metabolic process; metal ion binding; post-translational protein modification; small molecule metabolic process,PF00884;,,,,,,,,,ARSF_HUMAN,Homo sapiens (Human),glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687] comp25607_c0_seq1,312,38.7821,0.48937338,1,23,,2.00E-09,Q96JM7,Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1),Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1),GO:0016568; GO:0005634; GO:0006355; GO:0006351,"chromatin modification; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02820;PF00536;,7.00E-12,CHOYP_LMBL3.1.1,,,,,,,LMBL3_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp25627_c0_seq1,225,40.4444,0.65571895,5,13,,1.00E-27,Q75WS4,Cryptochrome DASH,Cryptochrome DASH,GO:0003913; GO:0006281; GO:0018298,DNA photolyase activity; DNA repair; protein-chromophore linkage,PF00875;PF03441;,,,,,,,,,CRYD_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298] comp2563_c0_seq1,212,48.5849,0.56265403,3,3,,2.00E-13,Q9BYK8,"Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)","Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)",GO:0005524; GO:0003677; GO:0044255; GO:0004386; GO:0030374; GO:0046872; GO:0005654; GO:0045944; GO:0044281; GO:0006351,"ATP binding; DNA binding; cellular lipid metabolic process; helicase activity; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; transcription, DNA-dependent",,7.00E-16,CHOYP_LOC100369525.1.2,,,,,,,PR285_HUMAN,Homo sapiens (Human),"cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp25672_c0_seq1,287,42.1603,0.31493001,5,20,,4.00E-15,Q8N6M6,Aminopeptidase O (AP-O) (EC 3.4.11.-),Aminopeptidase O (AP-O) (EC 3.4.11.-),GO:0004177; GO:0005737; GO:0019370; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; leukotriene biosynthetic process; metallopeptidase activity; proteolysis; zinc ion binding,PF09127;PF01433;,,,,,,,,,AMPO_HUMAN,Homo sapiens (Human),peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp25683_c0_seq1,229,46.2882,0.41667461,7,9,,6.00E-36,Q96PB1,CAS1 domain-containing protein 1,CAS1 domain-containing protein 1,GO:0016021,integral to membrane,PF07779;,7.00E-42,CHOYP_ISCW_ISCW021640.1.1,,,,,,,CASD1_HUMAN,Homo sapiens (Human), comp25684_c0_seq1,314,38.535,0.43701886,8,14,,4.00E-44,Q13042,Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6),Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6),GO:0005680; GO:0031145; GO:0051301; GO:0008283; GO:0005813; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979; GO:0005876,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cell proliferation; centrosome; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; spindle microtubule,,3.00E-36,CHOYP_LOC101158148.1.1,,,,,,,CDC16_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of mitotic nuclear division [GO:0007088]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp25701_c0_seq1,274,44.5255,0.75199252,0,21,,8.00E-16,Q16831,Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3),Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3),GO:0044206; GO:0042149; GO:0005829; GO:0009166; GO:0006206; GO:0046135; GO:0043097; GO:0046108; GO:0004850,UMP salvage; cellular response to glucose starvation; cytosol; nucleotide catabolic process; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; uridine metabolic process; uridine phosphorylase activity,PF01048;,,,,,,,,,UPP1_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218] comp25731_c0_seq1,254,40.1575,0.39459026,1,19,,3.00E-11,D0Z9R0,Tat-linked quality control protein TatD (Deoxyribonuclease TatD) (DNase TatD) (EC 3.1.21.-),3'-5' ssDNA/RNA exonuclease TatD (EC 3.1.11.-) (EC 3.1.13.-) (DNase TatD),GO:0005737; GO:0016888; GO:0046872; GO:0006515; GO:0090305,"cytoplasm; endodeoxyribonuclease activity, producing 5'-phosphomonoesters; metal ion binding; misfolded or incompletely synthesized protein catabolic process; nucleic acid phosphodiester bond hydrolysis",PF01026;,,,,,,,,,TATD_EDWTE,Edwardsiella tarda (strain EIB202), comp25732_c0_seq1,207,37.6812,0.55027739,2,16,,1.00E-20,P51798,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0005254; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; chloride channel activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,,,,,,,,,CLCN7_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810] comp25736_c0_seq1,222,49.5495,0.4644315,0,10,,7.00E-13,Q80V63,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_MOUSE,Mus musculus (Mouse),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp25742_c0_seq1,304,49.0132,0.49728799,26,0,,,,,,,,,,,2.00E-11,ruditapes_c11717,,,,,,, comp25750_c0_seq1,249,42.9719,0.96764404,5,18,,2.00E-46,P25916,Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4),Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4),GO:0031519; GO:0007420; GO:0003682; GO:0005737; GO:0048704; GO:0016573; GO:0016574; GO:0006959; GO:0001701; GO:2001234; GO:0000122; GO:0016604; GO:0030890; GO:0033092; GO:0051443; GO:0021903; GO:0043565; GO:0048103; GO:0006351; GO:0000151; GO:0008270,"PcG protein complex; brain development; chromatin binding; cytoplasm; embryonic skeletal system morphogenesis; histone acetylation; histone ubiquitination; humoral immune response; in utero embryonic development; negative regulation of apoptotic signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nuclear body; positive regulation of B cell proliferation; positive regulation of immature T cell proliferation in thymus; positive regulation of ubiquitin-protein ligase activity; rostrocaudal neural tube patterning; sequence-specific DNA binding; somatic stem cell division; transcription, DNA-dependent; ubiquitin ligase complex; zinc ion binding",PF16207;,3.00E-35,CHOYP_BMI1A.2.2,,,,,,,BMI1_MOUSE,Mus musculus (Mouse),"brain development [GO:0007420]; cellular process [GO:0009987]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-1 [GO:0071347]; DNA methylation [GO:0006306]; embryonic skeletal system development [GO:0048706]; embryonic skeletal system morphogenesis [GO:0048704]; hematopoietic stem cell homeostasis [GO:0061484]; histone acetylation [GO:0016573]; histone ubiquitination [GO:0016574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; rostrocaudal neural tube patterning [GO:0021903]; skeletal system development [GO:0001501]; somatic stem cell division [GO:0048103]; transcription, DNA-templated [GO:0006351]" comp25773_c0_seq1,264,44.3182,0.55373929,19,3,,1.00E-31,Q8TBG4,Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1),Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1),GO:0008453; GO:0006520; GO:0050459; GO:0005739; GO:0030170,alanine-glyoxylate transaminase activity; cellular amino acid metabolic process; ethanolamine-phosphate phospho-lyase activity; mitochondrion; pyridoxal phosphate binding,PF00202;,8.00E-36,CHOYP_LOC101064182.1.1,,,,,,,AT2L1_HUMAN,Homo sapiens (Human),phosphatidylethanolamine biosynthetic process [GO:0006646] comp25792_c0_seq1,275,45.8182,0.20861954,5,11,,2.00E-16,Q8BJZ3,Protein lifeguard 3 (Responsive to centrifugal force and shear stress gene 1 protein) (Protein RECS1) (Transmembrane BAX inhibitor motif-containing protein 1),Protein lifeguard 3 (Responsive to centrifugal force and shear stress gene 1 protein) (Protein RECS1) (Transmembrane BAX inhibitor motif-containing protein 1),GO:0010008; GO:0016021; GO:0005765; GO:0050848,endosome membrane; integral to membrane; lysosomal membrane; regulation of calcium-mediated signaling,,9.00E-61,CHOYP_BRAFLDRAFT_60532.1.1,,,,,,,LFG3_MOUSE,Mus musculus (Mouse),negative regulation of catalytic activity [GO:0043086]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of Fas signaling pathway [GO:1902045]; positive regulation of blood vessel remodeling [GO:2000504]; regulation of calcium-mediated signaling [GO:0050848] comp25796_c0_seq1,307,41.6938,0.30263156,3,15,,2.00E-16,Q64008,Ras-related protein Rab-34 (Ras-related homolog) (Ras-related protein Rab-39) (Ras-related protein Rah),Ras-related protein Rab-34 (Ras-related homolog) (Ras-related protein Rab-39) (Ras-related protein Rah),GO:0005525; GO:0003924; GO:0005794; GO:0005769; GO:0019001; GO:0045335; GO:0030670; GO:0090385; GO:0015031; GO:0001726; GO:0007264,GTP binding; GTPase activity; Golgi apparatus; early endosome; guanyl nucleotide binding; phagocytic vesicle; phagocytic vesicle membrane; phagosome-lysosome fusion; protein transport; ruffle; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAB34_MOUSE,Mus musculus (Mouse),antigen processing and presentation [GO:0019882]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]; lysosome localization [GO:0032418]; phagosome-lysosome fusion [GO:0090385]; phagosome maturation [GO:0090382]; protein localization to plasma membrane [GO:0072659]; small GTPase mediated signal transduction [GO:0007264] comp25823_c0_seq1,407,43.2432,0.69579326,14,8,,9.00E-43,O60260,E3 ubiquitin-protein ligase parkin (EC 6.3.2.-) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2),E3 ubiquitin-protein ligase parkin (Parkin) (EC 6.3.2.-) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2),GO:0005794; GO:0016235; GO:0070842; GO:0007417; GO:0005829; GO:0005783; GO:0005739; GO:0000422; GO:0032232; GO:0043524; GO:0001933; GO:0090201; GO:0070997; GO:0005634; GO:0048471; GO:0043123; GO:0070936; GO:0070534; GO:0051865; GO:0006513; GO:0042787; GO:0010506; GO:2000377; GO:0004842; GO:0008270,Golgi apparatus; aggresome; aggresome assembly; central nervous system development; cytosol; endoplasmic reticulum; mitochondrion; mitochondrion degradation; negative regulation of actin filament bundle assembly; negative regulation of neuron apoptotic process; negative regulation of protein phosphorylation; negative regulation of release of cytochrome c from mitochondria; neuron death; nucleus; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein K48-linked ubiquitination; protein K63-linked ubiquitination; protein autoubiquitination; protein monoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of autophagy; regulation of reactive oxygen species metabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF01485;PF00240;,7.00E-14,CHOYP_PRKN2.1.1,,,,,,,PRKN2_HUMAN,Homo sapiens (Human),"adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; cellular protein catabolic process [GO:0044257]; cellular protein metabolic process [GO:0044267]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; cellular response to unfolded protein [GO:0034620]; central nervous system development [GO:0007417]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; ERAD pathway [GO:0036503]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; macroautophagy [GO:0016236]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of autophagy [GO:0010506]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of dopamine secretion [GO:0014059]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid transport [GO:0032368]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of mitophagy [GO:1903146]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of synaptic vesicle transport [GO:1902803]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]; transcription, DNA-templated [GO:0006351]; zinc ion homeostasis [GO:0055069]" comp25829_c0_seq1,233,44.206,0.73069262,4,13,,,,,,,,,3.00E-27,CHOYP_BRAFLDRAFT_121518.1.1,,,,,,,,, comp25832_c0_seq1,437,44.3936,0.8382819,10,20,,1.00E-15,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp25841_c0_seq1,308,42.5325,0.65932416,4,22,,1.00E-11,Q9QZZ4,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,3.00E-41,CHOYP_LOC100901924.3.3,,,,,,,MYO15_MOUSE,Mus musculus (Mouse),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp25845_c0_seq1,303,43.5644,0.6460519,5,23,,1.00E-57,Q9ULJ6,Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17),Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17),GO:0048844; GO:0007569; GO:0005737; GO:0048589; GO:0003007; GO:0001701; GO:0016607; GO:0048146; GO:0045944; GO:0006351; GO:0001570; GO:0007296; GO:0008270,"artery morphogenesis; cell aging; cytoplasm; developmental growth; heart morphogenesis; in utero embryonic development; nuclear speck; positive regulation of fibroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; vasculogenesis; vitellogenesis; zinc ion binding",PF02891;,2.00E-50,CHOYP_BRAFLDRAFT_130685.1.1,,,,,,,ZMIZ1_HUMAN,Homo sapiens (Human),"artery morphogenesis [GO:0048844]; cell aging [GO:0007569]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296]" comp25847_c0_seq1,349,46.4183,0.32853837,12,19,,2.00E-10,Q54HW1,26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28),,,PF12796;,,,,,,,,,PSD10_DICDI,Dictyostelium discoideum (Slime mold), comp25876_c0_seq1,333,43.2432,0.39418137,0,36,,4.00E-36,Q6NSN2,Amine oxidase [flavin-containing] (EC 1.4.3.4) (Monoamine oxidase) (MAO) (Z-MAO),Amine oxidase [flavin-containing] (EC 1.4.3.4) (Monoamine oxidase) (MAO) (Z-MAO),GO:0006584; GO:0042402; GO:0016021; GO:0005741; GO:0042135; GO:0008131,catecholamine metabolic process; cellular biogenic amine catabolic process; integral to membrane; mitochondrial outer membrane; neurotransmitter catabolic process; primary amine oxidase activity,PF01593;,2.00E-13,CHOYP_AOFA.1.1,,,,,,,AOF_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),catecholamine metabolic process [GO:0006584]; cellular biogenic amine catabolic process [GO:0042402]; neurotransmitter catabolic process [GO:0042135] comp25883_c0_seq1,312,44.2308,0.92214752,8,9,,,,,,,,,2.00E-12,CHOYP_LOC100369716.1.1,,,,,,,,, comp25922_c0_seq1,254,39.3701,0.62424468,7,17,,2.00E-06,Q9EPS3,D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase),D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase),GO:0000139; GO:0050379; GO:0015012; GO:0030210; GO:0047464; GO:0016021,Golgi membrane; UDP-glucuronate 5'-epimerase activity; heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; heparosan-N-sulfate-glucuronate 5-epimerase activity; integral to membrane,PF06662;,,,,,,,,,GLCE_MOUSE,Mus musculus (Mouse),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] comp25938_c0_seq1,256,43.75,1.0684525,1,16,,2.00E-08,Q90Z12,Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a),Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a),GO:0030509; GO:0008283; GO:0033504; GO:0002088; GO:0043066; GO:0000122; GO:0014029; GO:0005634; GO:0021501; GO:0043565; GO:0006351,"BMP signaling pathway; cell proliferation; floor plate development; lens development in camera-type eye; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; neural crest formation; nucleus; prechordal plate formation; sequence-specific DNA binding; transcription, DNA-dependent",PF07527;PF00010;,,,,,,,,,HES4A_XENLA,Xenopus laevis (African clawed frog),"BMP signaling pathway [GO:0030509]; cell proliferation [GO:0008283]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest formation [GO:0014029]; prechordal plate formation [GO:0021501]; transcription, DNA-templated [GO:0006351]" comp2593_c0_seq1,263,62.3574,1.24853064,1,5,,2.00E-07,Q82B58,Putative ABC transporter ATP-binding protein SAV_5847 (EC 3.6.3.-),Putative ABC transporter ATP-binding protein SAV_5847 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; plasma membrane; transport,PF00005;,,,,,,,,,Y5847_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),transport [GO:0006810] comp25953_c0_seq1,230,42.6087,0.19242346,18,0,,6.00E-25,Q8BPU7,Engulfment and cell motility protein 1 (Protein ced-12 homolog),Engulfment and cell motility protein 1 (Protein ced-12 homolog),GO:0016601; GO:0030036; GO:0006915; GO:0006928; GO:0005737; GO:0005856; GO:0006911; GO:0005543; GO:0005886,"Rac protein signal transduction; actin cytoskeleton organization; apoptotic process; cellular component movement; cytoplasm; cytoskeleton; phagocytosis, engulfment; phospholipid binding; plasma membrane",PF11841;PF04727;PF16457;,7.00E-17,CHOYP_ELMO1.1.1,,,,,,,ELMO1_MOUSE,Mus musculus (Mouse),"actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; apoptotic process [GO:0006915]; cell migration [GO:0016477]; movement of cell or subcellular component [GO:0006928]; phagocytosis [GO:0006909]; phagocytosis, engulfment [GO:0006911]; positive regulation of GTPase activity [GO:0043547]; Rac protein signal transduction [GO:0016601]" comp25964_c0_seq1,493,39.7566,0.78330132,0,65,,1.00E-06,Q9P2G3,Kelch-like protein 14 (Protein interactor of Torsin-1A) (Printor) (Protein interactor of torsinA),Kelch-like protein 14 (Protein interactor of Torsin-1A) (Printor) (Protein interactor of torsinA),GO:0005829; GO:0005783; GO:0005789; GO:0043005; GO:0043025,cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; neuron projection; neuronal cell body,PF07707;PF00651;PF01344;,,,,,,,,,KLH14_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp25986_c0_seq1,396,40.404,0.37218987,5,21,,1.00E-13,Q9Y5W7,Sorting nexin-14,Sorting nexin-14,GO:0007154; GO:0016021; GO:0035091; GO:0015031; GO:0038032,cell communication; integral to membrane; phosphatidylinositol binding; protein transport; termination of G-protein coupled receptor signaling pathway,PF08628;PF00787;PF02194;PF00615;,,,,,,,,,SNX14_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; protein transport [GO:0015031] comp25989_c0_seq1,216,44.9074,0.65138617,2,16,,8.00E-24,Q9CWN7,CCR4-NOT transcription complex subunit 11,CCR4-NOT transcription complex subunit 11,GO:0030014; GO:0005737; GO:0031047; GO:0005634; GO:0006355; GO:0006417; GO:0006351,"CCR4-NOT complex; cytoplasm; gene silencing by RNA; nucleus; regulation of transcription, DNA-dependent; regulation of translation; transcription, DNA-dependent",PF10155;,8.00E-35,CHOYP_LOC100367053.1.1,,,,,,,CB029_MOUSE,Mus musculus (Mouse),"gene silencing by RNA [GO:0031047]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]" comp25998_c0_seq1,325,46.4615,0.28748068,9,15,,5.00E-39,P70700,DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),GO:0003677; GO:0005736; GO:0003899; GO:0009790; GO:0007566; GO:0046872; GO:0017126; GO:0005654; GO:0009303; GO:0032549,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; embryo development; embryo implantation; metal ion binding; nucleologenesis; nucleoplasm; rRNA transcription; ribonucleoside binding,PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;,1.00E-14,CHOYP_BRAFLDRAFT_223894.1.1,,,,,,,RPA2_MOUSE,Mus musculus (Mouse),chromatin silencing at rDNA [GO:0000183]; embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; rRNA transcription [GO:0009303]; transcription initiation from RNA polymerase I promoter [GO:0006361] comp26034_c0_seq1,266,39.0977,0.7973237,3,18,,9.00E-17,Q4KL91,Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4),Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4),GO:0006865; GO:0016021; GO:0015293,amino acid transport; integral to membrane; symporter activity,PF01490;,,,,,,,,,S36A4_XENLA,Xenopus laevis (African clawed frog),amino acid transport [GO:0006865] comp26059_c0_seq1,521,38.0038,0.79898254,11,17,,2.00E-33,Q8VI63,MOB kinase activator 2 (Mob2 homolog) (Mps one binder kinase activator-like 2) (Ovary-specific MOB-like protein),MOB kinase activator 2 (Mob2 homolog) (Mps one binder kinase activator-like 2) (Ovary-specific MOB-like protein),GO:0030036; GO:0005737; GO:0046872; GO:0044306; GO:0005634; GO:0048471; GO:0010976; GO:0001934,actin cytoskeleton organization; cytoplasm; metal ion binding; neuron projection terminus; nucleus; perinuclear region of cytoplasm; positive regulation of neuron projection development; positive regulation of protein phosphorylation,PF03637;,5.00E-36,CHOYP_ISCW_ISCW022842.1.1,,,,,,,MOB2_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein phosphorylation [GO:0001934] comp26061_c0_seq1,395,40,0.69976352,4,30,,5.00E-23,P08049,Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10),Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10),GO:0030424; GO:0050435; GO:0005903; GO:0071492; GO:0071493; GO:0071345; GO:0046449; GO:0030425; GO:0016021; GO:0001822; GO:0004222; GO:0044306; GO:0042277; GO:0005886; GO:0006508; GO:0090399; GO:0019233; GO:0008021; GO:0008270,axon; beta-amyloid metabolic process; brush border; cellular response to UV-A; cellular response to UV-B; cellular response to cytokine stimulus; creatinine metabolic process; dendrite; integral to membrane; kidney development; metalloendopeptidase activity; neuron projection terminus; peptide binding; plasma membrane; proteolysis; replicative senescence; sensory perception of pain; synaptic vesicle; zinc ion binding,PF01431;PF05649;,,,,,,,,,NEP_RABIT,Oryctolagus cuniculus (Rabbit),beta-amyloid metabolic process [GO:0050435]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233] comp26112_c0_seq1,357,58.5434,1.11527355,0,28,,2.00E-09,P0AF24,Ribonucleotide monophosphatase NagD (EC 3.1.3.5),Ribonucleotide monophosphatase NagD (EC 3.1.3.5),GO:0008253; GO:0005975; GO:0000287; GO:0034655,5'-nucleotidase activity; carbohydrate metabolic process; magnesium ion binding; nucleobase-containing compound catabolic process,PF13344;,,,,,,,,,NAGD_ECOLI,Escherichia coli (strain K12),carbohydrate metabolic process [GO:0005975]; UMP catabolic process [GO:0046050] comp26113_c0_seq1,281,42.7046,1.1374934,8,16,,4.00E-36,Q8STF0,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,4.00E-15,CHOYP_CALM.37.50,1.00E-19,ruditapes_c3243,,,,,CALM_STRIE,Strongylocentrotus intermedius (Sea urchin), comp2611_c0_seq1,217,62.212,1.00617521,0,3,,2.00E-33,B9MG14,ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Endopeptidase Clp),ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Endopeptidase Clp),GO:0005524; GO:0005737; GO:0006508; GO:0004252,ATP binding; cytoplasm; proteolysis; serine-type endopeptidase activity,PF00574;,,,,,,,,,CLPP_ACIET,Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)), comp26123_c0_seq1,352,44.0341,0.88339051,14,11,,2.00E-34,Q5EAU0,Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A),Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A),GO:0005887; GO:0051928; GO:0015279,integral to plasma membrane; positive regulation of calcium ion transport; store-operated calcium channel activity,PF07856;,1.00E-15,CHOYP_CRCM1.2.2,,,,,,,CRCM1_XENLA,Xenopus laevis (African clawed frog),adaptive immune response [GO:0002250]; positive regulation of calcium ion transport [GO:0051928] comp26156_c0_seq1,253,45.0593,0.57263374,3,18,,9.00E-24,Q8R4P9,Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10),Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP7_MOUSE,Mus musculus (Mouse), comp26160_c0_seq1,285,46.3158,0.46055317,4,15,,1.00E-09,Q9UKP5,A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-),GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS6_HUMAN,Homo sapiens (Human),aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976] comp26180_c0_seq1,760,35.9211,0.82270413,8,35,,7.00E-09,Q1PRL4,E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71),GO:0000082; GO:0000932; GO:0008543; GO:0035198; GO:0010586; GO:0035278; GO:0001843; GO:0021915; GO:2000637; GO:0051865; GO:0060964; GO:2000177; GO:0072089; GO:0004842; GO:0008270,G1/S transition of mitotic cell cycle; cytoplasmic mRNA processing body; fibroblast growth factor receptor signaling pathway; miRNA binding; miRNA metabolic process; negative regulation of translation involved in gene silencing by miRNA; neural tube closure; neural tube development; positive regulation of gene silencing by miRNA; protein autoubiquitination; regulation of gene silencing by miRNA; regulation of neural precursor cell proliferation; stem cell proliferation; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;,,,,,,,,,LIN41_CHICK,Gallus gallus (Chicken),fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] comp26181_c0_seq1,232,45.2586,0.51097441,3,19,,7.00E-17,Q460N3,Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3),GO:0003950; GO:0005634; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR15_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp26216_c0_seq1,293,35.1536,0.89362743,0,19,,5.00E-12,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp26234_c0_seq1,462,59.7403,1.07538511,0,28,,6.00E-17,P12679,Aminodeoxychorismate synthase component 1 (ADC synthase) (ADCS) (EC 2.6.1.85) (4-amino-4-deoxychorismate synthase component 1),Aminodeoxychorismate synthase component 1 (ADC synthase) (ADCS) (EC 2.6.1.85) (4-amino-4-deoxychorismate synthase component 1),GO:0046820; GO:0046656; GO:0000287; GO:0016833; GO:0046654,4-amino-4-deoxychorismate synthase activity; folic acid biosynthetic process; magnesium ion binding; oxo-acid-lyase activity; tetrahydrofolate biosynthetic process,PF04715;PF00425;,,,,,,,,,PABB_ENTAE,Enterobacter aerogenes (Aerobacter aerogenes),folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654] comp26265_c0_seq1,604,38.4106,0.40468338,7,40,,5.00E-27,Q9JLQ2,ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2),ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2),GO:0008060; GO:0005654; GO:0043547; GO:0032312; GO:0008270,ARF GTPase activator activity; nucleoplasm; positive regulation of GTPase activity; regulation of ARF GTPase activity; zinc ion binding,PF12796;PF01412;PF12205;PF08518;,,,,,,,,,GIT2_MOUSE,Mus musculus (Mouse),behavioral response to pain [GO:0048266] comp26272_c0_seq1,500,46.6,0.67218516,15,11,,7.00E-13,Q8QFV0,Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,2.00E-27,CHOYP_LOC655919.1.1,,,,,,,KCNT1_CHICK,Gallus gallus (Chicken), comp26284_c0_seq1,312,44.2308,0.46647275,4,17,,2.00E-08,Q8K1X1,WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2),WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2),GO:0005929; GO:0005737; GO:0016021; GO:0005634,cilium; cytoplasm; integral to membrane; nucleus,,,,,,,,,,WDR11_MOUSE,Mus musculus (Mouse), comp26288_c0_seq1,501,41.9162,1.04878245,38,0,,2.00E-20,Q9BXS9,Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1),Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1),GO:0030165; GO:0038166; GO:0015301; GO:0016324; GO:0016323; GO:0015106; GO:0031526; GO:0071320; GO:0071332; GO:0071346; GO:0005254; GO:0034707; GO:0015108; GO:0030659; GO:0005783; GO:0042045; GO:0015660; GO:0015659; GO:0016021; GO:0005887; GO:0050892; GO:0051454; GO:0015797; GO:0019531; GO:0046724; GO:0005886; GO:2001150; GO:0070528; GO:0051453; GO:0008271; GO:0048240; GO:0097225; GO:0015116; GO:0008272; GO:0030321; GO:0012506,PDZ domain binding; angiotensin-mediated signaling pathway; anion:anion antiporter activity; apical plasma membrane; basolateral plasma membrane; bicarbonate transmembrane transporter activity; brush border membrane; cellular response to cAMP; cellular response to fructose stimulus; cellular response to interferon-gamma; chloride channel activity; chloride channel complex; chloride transmembrane transporter activity; cytoplasmic vesicle membrane; endoplasmic reticulum; epithelial fluid transport; formate efflux transmembrane transporter activity; formate uptake transmembrane transporter activity; integral to membrane; integral to plasma membrane; intestinal absorption; intracellular pH elevation; mannitol transport; oxalate transmembrane transporter activity; oxalic acid secretion; plasma membrane; positive regulation of dipeptide transmembrane transport; protein kinase C signaling cascade; regulation of intracellular pH; secondary active sulfate transmembrane transporter activity; sperm capacitation; sperm midpiece; sulfate transmembrane transporter activity; sulfate transport; transepithelial chloride transport; vesicle membrane,PF01740;PF00916;,,,,,,,,,S26A6_HUMAN,Homo sapiens (Human),angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to fructose stimulus [GO:0071332]; cellular response to interferon-gamma [GO:0071346]; chloride transport [GO:0006821]; epithelial fluid transport [GO:0042045]; formate transport [GO:0015724]; intestinal absorption [GO:0050892]; intracellular pH elevation [GO:0051454]; ion transport [GO:0006811]; mannitol transport [GO:0015797]; oxalate transport [GO:0019532]; oxalic acid secretion [GO:0046724]; positive regulation of dipeptide transmembrane transport [GO:2001150]; protein kinase C signaling [GO:0070528]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]; sulfate transport [GO:0008272]; transepithelial chloride transport [GO:0030321]; transepithelial transport [GO:0070633] comp26302_c0_seq1,760,34.4737,1.14388125,50,0,,4.00E-09,P04630,Calmodulin-like protein,Calmodulin-like protein,GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CALL_CAEEL,Caenorhabditis elegans, comp26317_c0_seq1,260,46.1538,0.87098063,3,21,,2.00E-11,Q90592,"Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2)","Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2)",GO:0005975; GO:0005355; GO:0015758; GO:0016021; GO:0005886; GO:0044281,carbohydrate metabolic process; glucose transmembrane transporter activity; glucose transport; integral to membrane; plasma membrane; small molecule metabolic process,PF00083;,4.00E-14,CHOYP_GTR1.1.1,,,,,,,GTR2_CHICK,Gallus gallus (Chicken),glucose transport [GO:0015758] comp2631_c0_seq1,281,45.5516,1.10184546,11,0,,9.00E-08,Q9ULI1,Leucine-rich repeat and WD repeat-containing protein KIAA1239,NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239),,,PF13271;,,,,,,,,,K1239_HUMAN,Homo sapiens (Human), comp26329_c0_seq1,303,46.5347,0.80686873,0,22,,2.00E-19,Q99NF1,"Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)","Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)",GO:0016121; GO:0016116; GO:0046872; GO:0005739; GO:0016702; GO:0051881; GO:2000377; GO:0042574; GO:0042573,"carotene catabolic process; carotenoid metabolic process; metal ion binding; mitochondrion; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; regulation of mitochondrial membrane potential; regulation of reactive oxygen species metabolic process; retinal metabolic process; retinoic acid metabolic process",PF03055;,,,,,,,,,BCDO2_MOUSE,Mus musculus (Mouse),carotene catabolic process [GO:0016121]; carotene metabolic process [GO:0016119]; carotenoid metabolic process [GO:0016116]; oxidation-reduction process [GO:0055114]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; xanthophyll metabolic process [GO:0016122] comp26344_c0_seq1,357,44.8179,0.39162676,20,8,,5.00E-38,P10180,Homeobox protein cut,Homeobox protein cut,GO:0061332; GO:0048098; GO:0007417; GO:0070983; GO:0008585; GO:0060288; GO:0008587; GO:0000278; GO:0045746; GO:0000122; GO:0005634; GO:0030713; GO:0007422; GO:0007605; GO:0003700; GO:0035277; GO:0000976; GO:0006351,"Malpighian tubule bud morphogenesis; antennal joint development; central nervous system development; dendrite guidance; female gonad development; formation of a compartment boundary; imaginal disc-derived wing margin morphogenesis; mitotic cell cycle; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; ovarian follicle cell stalk formation; peripheral nervous system development; sensory perception of sound; sequence-specific DNA binding transcription factor activity; spiracle morphogenesis, open tracheal system; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF02376;PF00046;,3.00E-62,CHOYP_CUX1.2.2,,,,,,,CUT_DROME,Drosophila melanogaster (Fruit fly),"antennal development [GO:0007469]; antennal joint development [GO:0048098]; cell fate commitment [GO:0045165]; central nervous system development [GO:0007417]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; female gonad development [GO:0008585]; formation of a compartment boundary [GO:0060288]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cell cycle [GO:0000278]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ boundary specification [GO:0008052]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of sound [GO:0007605]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription, DNA-templated [GO:0006351]" comp26345_c0_seq1,249,38.9558,0.88418756,8,10,,2.00E-12,Q91ZY8,E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),GO:0030054; GO:0005856; GO:0030425; GO:0035544; GO:0045955; GO:0043161; GO:0008021; GO:0016079; GO:0004842; GO:0008270,cell junction; cytoskeleton; dendrite; negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; proteasomal ubiquitin-dependent protein catabolic process; synaptic vesicle; synaptic vesicle exocytosis; ubiquitin-protein ligase activity; zinc ion binding,PF00041;PF00622;PF00643;,,,,,,,,,TRIM9_RAT,Rattus norvegicus (Rat),negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079] comp26348_c0_seq1,298,37.2483,0.30000338,7,21,,4.00E-34,Q969X5,Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32),Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32),GO:0006888; GO:0000139; GO:0005789; GO:0005793; GO:0033116; GO:0016021,ER to Golgi vesicle-mediated transport; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane,PF07970;,5.00E-39,CHOYP_ERGI1.1.1,,,,,,,ERGI1_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888] comp26350_c0_seq1,223,46.1883,0.1748669,3,9,,1.00E-10,Q5XKL5,BTB/POZ domain-containing protein 8,BTB/POZ domain-containing protein 8,GO:0005634,nucleus,PF00651;,,,,,,,,,BTBD8_HUMAN,Homo sapiens (Human),"positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]" comp26355_c0_seq1,383,43.342,0.54339993,6,18,,4.00E-43,C3YZ51,Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5),Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5),GO:0005524; GO:0048037; GO:0046872; GO:0016616,"ATP binding; cofactor binding; metal ion binding; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",PF00899;,4.00E-73,CHOYP_UBA5.1.2,,,,,,,UBA5_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),cyclic threonylcarbamoyladenosine biosynthetic process [GO:0061504]; protein ufmylation [GO:0071569] comp26357_c0_seq1,402,43.2836,0.58575944,11,13,,1.00E-13,Q8IYR2,SET and MYND domain-containing protein 4 (EC 2.1.1.-),SET and MYND domain-containing protein 4 (EC 2.1.1.-),GO:0046872; GO:0008168,metal ion binding; methyltransferase activity,PF00856;PF01753;,,,,,,,,,SMYD4_HUMAN,Homo sapiens (Human), comp26361_c0_seq1,350,45.4286,0.22285896,1,24,,2.00E-15,Q5DRD5,Protocadherin beta-14 (PCDH-beta-14),Protocadherin beta-14 (PCDH-beta-14),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;,,,,,,,,,PCDBE_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp26368_c0_seq1,273,48.3516,0.88388283,0,21,,2.00E-34,P52785,Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E),Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E),GO:0005524; GO:0005525; GO:0004383; GO:0016021; GO:0035556; GO:0004672; GO:0007601,ATP binding; GTP binding; guanylate cyclase activity; integral to membrane; intracellular signal transduction; protein kinase activity; visual perception,PF01094;PF00211;PF07701;PF07714;,1.00E-21,CHOYP_ANPRB.2.2,4.00E-19,ruditapes_c24373,,,,,GUC2E_MOUSE,Mus musculus (Mouse),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; receptor guanylyl cyclase signaling pathway [GO:0007168]; visual perception [GO:0007601] comp26369_c0_seq1,355,49.2958,0.52592413,12,11,,9.00E-43,Q03042,"cGMP-dependent protein kinase, isozyme 1 (cGK) (EC 2.7.11.12)","cGMP-dependent protein kinase, isozyme 1 (cGK) (EC 2.7.11.12)",GO:0005524; GO:0030553; GO:0004692; GO:0007526,ATP binding; cGMP binding; cGMP-dependent protein kinase activity; larval somatic muscle development,PF00027;PF00069;,8.00E-50,CHOYP_LOC100533328.1.1,,,,,,,KGP1_DROME,Drosophila melanogaster (Fruit fly),larval somatic muscle development [GO:0007526]; protein phosphorylation [GO:0006468]; regulation of glucose metabolic process [GO:0010906] comp26400_c0_seq1,221,48.4163,0.9314876,4,10,,4.00E-20,Q91ZY8,E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),GO:0030054; GO:0005856; GO:0030425; GO:0035544; GO:0045955; GO:0043161; GO:0008021; GO:0016079; GO:0004842; GO:0008270,cell junction; cytoskeleton; dendrite; negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; proteasomal ubiquitin-dependent protein catabolic process; synaptic vesicle; synaptic vesicle exocytosis; ubiquitin-protein ligase activity; zinc ion binding,PF00041;PF00622;PF00643;,,,,,,,,,TRIM9_RAT,Rattus norvegicus (Rat),negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079] comp26403_c0_seq1,247,46.5587,0.38799134,2,15,,3.00E-11,Q9U2C4,Probable N-acetylgalactosaminyltransferase 9 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9) (pp-GaNTase 9),Probable N-acetylgalactosaminyltransferase 9 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9) (pp-GaNTase 9),GO:0000139; GO:0016021; GO:0006486; GO:0016757,"Golgi membrane; integral to membrane; protein glycosylation; transferase activity, transferring glycosyl groups",PF00535;PF00652;,3.00E-16,CHOYP_GALT9.1.1,,,,,,,GALT9_CAEEL,Caenorhabditis elegans,protein glycosylation [GO:0006486] comp26409_c0_seq1,305,36.0656,0.91042301,3,15,,2.00E-17,Q80SU7,Interferon-induced very large GTPase 1 (Very large-inducible GTPase-1) (VLIG-1),Interferon-induced very large GTPase 1 (Very large-inducible GTPase-1) (VLIG-1),GO:0005525; GO:0005829; GO:0005634,GTP binding; cytosol; nucleus,,,,,,,,,,GVIN1_MOUSE,Mus musculus (Mouse), comp26428_c0_seq1,500,42.4,0.67484106,2,22,,2.00E-11,O57429,Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2),Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2),GO:0046872; GO:0048471; GO:0016579; GO:0004221; GO:0006511; GO:0004843,metal ion binding; perinuclear region of cytoplasm; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00443;,,,,,,,,,UBP2_CHICK,Gallus gallus (Chicken),protein deubiquitination [GO:0016579]; rhythmic process [GO:0048511]; ubiquitin-dependent protein catabolic process [GO:0006511] comp26428_c0_seq2,422,42.4171,0.63945937,6,0,,6.00E-49,P0C8Z3,Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22),Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22),GO:0010485; GO:0000124; GO:0007049; GO:0016578; GO:0016574; GO:0030374; GO:0045931; GO:0045893; GO:0006351; GO:0004221; GO:0006511; GO:0004843; GO:0008270,"H4 histone acetyltransferase activity; SAGA complex; cell cycle; histone deubiquitination; histone ubiquitination; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding",PF00443;PF02148;,3.00E-57,CHOYP_UBP22.3.3,,,,,,,UBP22_BOVIN,Bos taurus (Bovine),"cell cycle [GO:0007049]; histone deubiquitination [GO:0016578]; histone ubiquitination [GO:0016574]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp26432_c0_seq1,244,36.8852,0.62469178,10,4,,1.00E-12,Q6QI06,Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo),Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo),GO:0031929; GO:0031932; GO:0031532; GO:0009790; GO:0032008; GO:0030838; GO:0050731; GO:0032314; GO:0030334; GO:0051896; GO:0043022,TOR signaling cascade; TORC2 complex; actin cytoskeleton reorganization; embryo development; positive regulation of TOR signaling cascade; positive regulation of actin filament polymerization; positive regulation of peptidyl-tyrosine phosphorylation; regulation of Rac GTPase activity; regulation of cell migration; regulation of protein kinase B signaling cascade; ribosome binding,PF14663;PF14666;PF14664;PF14665;PF14668;,,,,,,,,,RICTR_MOUSE,Mus musculus (Mouse),actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp26444_c0_seq1,479,44.4676,0.26181932,14,10,,5.00E-46,Q9P1Q0,Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p),Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p),GO:0000938; GO:0040007; GO:0048873; GO:0050881; GO:0060052; GO:0015031; GO:0042147,"GARP complex; growth; homeostasis of number of cells within a tissue; musculoskeletal movement; neurofilament cytoskeleton organization; protein transport; retrograde transport, endosome to Golgi",PF07928;PF10475;,1.00E-37,CHOYP_VPS54.1.1,,,,,,,VPS54_HUMAN,Homo sapiens (Human),"Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp26448_c0_seq1,382,49.4764,1.17538882,6,17,,1.00E-06,P30205,Antigen WC1.1,Antigen WC1.1,GO:0005576; GO:0016020; GO:0005044,extracellular region; membrane; scavenger receptor activity,PF00530;,,,,,,,,,WC11_BOVIN,Bos taurus (Bovine), comp26455_c0_seq1,284,47.5352,0.446714,8,16,,9.00E-22,Q13569,G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG),G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG),GO:0080111; GO:0016605; GO:0001104; GO:0016568; GO:0003684; GO:0045008; GO:0009790; GO:0006298; GO:0030983; GO:0035562; GO:0032091; GO:0000122; GO:0005654; GO:0042803; GO:0008263,DNA demethylation; PML body; RNA polymerase II transcription cofactor activity; chromatin modification; damaged DNA binding; depyrimidination; embryo development; mismatch repair; mismatched DNA binding; negative regulation of chromatin binding; negative regulation of protein binding; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; protein homodimerization activity; pyrimidine-specific mismatch base pair DNA N-glycosylase activity,PF03167;,1.00E-20,CHOYP_LOC586471.1.1,,,,,,,TDG_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; chromatin modification [GO:0016568]; depyrimidination [GO:0045008]; DNA demethylation [GO:0080111]; embryo development [GO:0009790]; mismatch repair [GO:0006298]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oxidative DNA demethylation [GO:0035511]; protein sumoylation [GO:0016925]; regulation of gene expression, epigenetic [GO:0040029]; transcription, DNA-templated [GO:0006351]" comp26456_c0_seq1,304,41.1184,0.64653588,10,18,,4.00E-22,Q3UR70,Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1),Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1),GO:0005737; GO:0006886; GO:0016020; GO:0006355; GO:0007165; GO:0005083; GO:0016192,"cytoplasm; intracellular protein transport; membrane; regulation of transcription, DNA-dependent; signal transduction; small GTPase regulator activity; vesicle-mediated transport",PF00637;PF00780;PF10366;PF10367;,1.00E-20,CHOYP_BRAFLDRAFT_268910.1.1,,,,,,,TGFA1_MOUSE,Mus musculus (Mouse),"endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]" comp26472_c0_seq1,245,48.1633,1.07991264,1,26,,7.00E-26,Q16831,Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3),Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3),GO:0044206; GO:0042149; GO:0005829; GO:0009166; GO:0006206; GO:0046135; GO:0043097; GO:0046108; GO:0004850,UMP salvage; cellular response to glucose starvation; cytosol; nucleotide catabolic process; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; uridine metabolic process; uridine phosphorylase activity,PF01048;,4.00E-20,CHOYP_LOC100876012.1.1,,,,,,,UPP1_HUMAN,Homo sapiens (Human),cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218] comp2647_c0_seq1,229,42.7948,0.39655929,6,0,,5.00E-21,P41925,Ras-like GTP-binding protein RYL2,Ras-like GTP-binding protein RYL2,GO:0005525; GO:0005886; GO:0015031; GO:0007264,GTP binding; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,8.00E-54,CHOYP_LOC100115628.1.1,,,,,,,RYL2_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),"intracellular protein transport [GO:0006886]; negative regulation of vacuole fusion, non-autophagic [GO:0061192]; small GTPase mediated signal transduction [GO:0007264]" comp26480_c0_seq1,217,44.2396,0.37848026,0,21,,2.00E-06,Q7XJR2,"Probable anion transporter 3, chloroplastic (Phosphate transporter PHT4;2)","Probable anion transporter 3, chloroplastic (Phosphate transporter PHT4;2)",GO:0031969; GO:0005315; GO:0016021; GO:0009536,chloroplast membrane; inorganic phosphate transmembrane transporter activity; integral to membrane; plastid,PF07690;,3.00E-40,CHOYP_PHUM_PHUM504500.1.1,,,,,,,ANTR3_ARATH,Arabidopsis thaliana (Mouse-ear cress),anion transmembrane transport [GO:0098656] comp26509_c0_seq1,455,37.3626,0.39446557,10,16,,1.00E-10,A2AAY5,SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains),SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains),GO:0042169; GO:0060612; GO:0060348; GO:0007154; GO:0030154; GO:0030054; GO:0042995; GO:0005737; GO:0022617; GO:0001654; GO:0007507; GO:0080025; GO:0032266; GO:0070273; GO:0010314; GO:0002102; GO:0071800; GO:0045600; GO:0072657; GO:0006801,"SH2 domain binding; adipose tissue development; bone development; cell communication; cell differentiation; cell junction; cell projection; cytoplasm; extracellular matrix disassembly; eye development; heart development; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; podosome; podosome assembly; positive regulation of fat cell differentiation; protein localization to membrane; superoxide metabolic process",PF00787;PF00018;PF07653;,,,,,,,,,SPD2B_MOUSE,Mus musculus (Mouse),adipose tissue development [GO:0060612]; bone development [GO:0060348]; cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; positive regulation of fat cell differentiation [GO:0045600]; protein localization to membrane [GO:0072657]; skeletal system development [GO:0001501]; superoxide metabolic process [GO:0006801] comp26515_c0_seq1,420,44.7619,0.28747176,10,26,,2.00E-39,P48651,Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I),Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I),GO:0005789; GO:0016021; GO:0006659; GO:0016740,endoplasmic reticulum membrane; integral to membrane; phosphatidylserine biosynthetic process; transferase activity,PF03034;,,,,,,,,,PTSS1_HUMAN,Homo sapiens (Human),phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654] comp26519_c0_seq1,244,43.4426,0.62478281,10,8,,,,,,,,,,,4.00E-11,ruditapes_c7564,,,,,,, comp26522_c0_seq1,320,40.9375,0.67532216,16,6,,4.00E-14,Q7Z402,Transmembrane channel-like protein 7,Transmembrane channel-like protein 7,GO:0016021; GO:0006811,integral to membrane; ion transport,PF07810;,,,,,,,,,TMC7_HUMAN,Homo sapiens (Human),ion transport [GO:0006811] comp26531_c0_seq1,288,43.0556,0.92161621,4,12,,,,,,,,,,,5.00E-11,ruditapes2_c1122,,,,,,, comp26540_c0_seq1,359,44.2897,0.29325741,18,6,,1.00E-28,Q8N0W3,L-fucose kinase (Fucokinase) (EC 2.7.1.52),L-fucose kinase (Fucokinase) (EC 2.7.1.52),GO:0005524; GO:0005737; GO:0050201,ATP binding; cytoplasm; fucokinase activity,PF07959;PF08544;PF00288;,2.00E-19,CHOYP_FUK.1.1,,,,,,,FUK_HUMAN,Homo sapiens (Human), comp26555_c0_seq1,535,49.3458,1.01801795,1,53,,4.00E-33,P22003,Bone morphogenetic protein 5 (BMP-5),Bone morphogenetic protein 5 (BMP-5),GO:0051216; GO:0005125; GO:0005615; GO:0040007; GO:0030539; GO:0031988; GO:0032348; GO:0008285; GO:2000065; GO:0010719; GO:1902042; GO:0043569; GO:0071676; GO:0001503; GO:0007389; GO:2000105; GO:1900006; GO:0050679; GO:0010862; GO:0045944; GO:0001501; GO:0003323,cartilage development; cytokine activity; extracellular space; growth; male genitalia development; membrane-bounded vesicle; negative regulation of aldosterone biosynthetic process; negative regulation of cell proliferation; negative regulation of cortisol biosynthetic process; negative regulation of epithelial to mesenchymal transition; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of mononuclear cell migration; ossification; pattern specification process; positive regulation of DNA-dependent DNA replication; positive regulation of dendrite development; positive regulation of epithelial cell proliferation; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; skeletal system development; type B pancreatic cell development,PF00019;PF00688;,2.00E-16,CHOYP_LOC100650311.1.1,,,,,,,BMP5_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; growth [GO:0040007]; male genitalia development [GO:0030539]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of steroid biosynthetic process [GO:0010894]; ossification [GO:0001503]; pattern specification process [GO:0007389]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-dependent DNA replication [GO:2000105]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; type B pancreatic cell development [GO:0003323] comp26576_c0_seq1,260,43.8462,0.68392758,0,14,,2.00E-24,P97479,Unconventional myosin-VIIa,Unconventional myosin-VIIa,GO:0005524; GO:0030048; GO:0016324; GO:0060088; GO:0005516; GO:0005938; GO:0005829; GO:0050957; GO:0006886; GO:0005765; GO:0007040; GO:0042470; GO:0000146; GO:0016459; GO:0001845; GO:0032391; GO:0001917; GO:0001750; GO:0051904; GO:0048563; GO:0007605; GO:0032420; GO:0045202; GO:0007601,ATP binding; actin filament-based movement; apical plasma membrane; auditory receptor cell stereocilium organization; calmodulin binding; cell cortex; cytosol; equilibrioception; intracellular protein transport; lysosomal membrane; lysosome organization; melanosome; microfilament motor activity; myosin complex; phagolysosome assembly; photoreceptor connecting cilium; photoreceptor inner segment; photoreceptor outer segment; pigment granule transport; post-embryonic organ morphogenesis; sensory perception of sound; stereocilium; synapse; visual perception,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_MOUSE,Mus musculus (Mouse),actin filament-based movement [GO:0030048]; auditory receptor cell differentiation [GO:0042491]; auditory receptor cell stereocilium organization [GO:0060088]; cell projection organization [GO:0030030]; equilibrioception [GO:0050957]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagocytosis [GO:0006909]; phagolysosome assembly [GO:0001845]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; post-embryonic organ morphogenesis [GO:0048563]; sensory perception [GO:0007600]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp26576_c0_seq2,255,44.3137,0.68040913,2,0,,4.00E-18,Q17LW0,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp26589_c0_seq1,519,40.0771,0.24780877,10,35,,1.00E-14,Q8C3S2,Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7),Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7),GO:0016021,integral to membrane,PF10363;PF10304;,,,,,,,,,TMCO7_MOUSE,Mus musculus (Mouse), comp26597_c0_seq1,514,40.856,0.28976104,17,26,,5.00E-23,Q8BSY0,Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase),Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase),GO:0097202; GO:0032237; GO:0070588; GO:0071277; GO:0032541; GO:0005737; GO:0060325; GO:0030176; GO:0016021; GO:0035108; GO:0008285; GO:0060021; GO:0007389; GO:0004597; GO:0042264; GO:0005886; GO:0010524; GO:0090316; GO:0045862; GO:0045893; GO:0031585; GO:1901879; GO:0031647; GO:0033198,"activation of cysteine-type endopeptidase activity; activation of store-operated calcium channel activity; calcium ion transmembrane transport; cellular response to calcium ion; cortical endoplasmic reticulum; cytoplasm; face morphogenesis; integral to endoplasmic reticulum membrane; integral to membrane; limb morphogenesis; negative regulation of cell proliferation; palate development; pattern specification process; peptide-aspartate beta-dioxygenase activity; peptidyl-aspartic acid hydroxylation; plasma membrane; positive regulation of calcium ion transport into cytosol; positive regulation of intracellular protein transport; positive regulation of proteolysis; positive regulation of transcription, DNA-dependent; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; regulation of protein depolymerization; regulation of protein stability; response to ATP",PF05279;PF05118;,,,,,,,,,ASPH_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion transmembrane transport [GO:0070588]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell proliferation [GO:0008285]; palate development [GO:0060021]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]" comp26598_c0_seq1,760,42.7632,0.51874664,52,0,,9.00E-100,O15118,Niemann-Pick C1 protein,Niemann-Pick C1 protein,GO:0005794; GO:0007628; GO:0006914; GO:0008206; GO:0071404; GO:0071383; GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0006897; GO:0005783; GO:0005576; GO:0008158; GO:0005887; GO:0031902; GO:0005765; GO:0007041; GO:0045121; GO:0016242; GO:0005635; GO:0048471; GO:0006486; GO:0042493; GO:0015248; GO:0004888; GO:0031982,Golgi apparatus; adult walking behavior; autophagy; bile acid metabolic process; cellular response to low-density lipoprotein particle stimulus; cellular response to steroid hormone stimulus; cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; endocytosis; endoplasmic reticulum; extracellular region; hedgehog receptor activity; integral to plasma membrane; late endosome membrane; lysosomal membrane; lysosomal transport; membrane raft; negative regulation of macroautophagy; nuclear envelope; perinuclear region of cytoplasm; protein glycosylation; response to drug; sterol transporter activity; transmembrane signaling receptor activity; vesicle,PF16414;PF02460;PF12349;,5.00E-76,CHOYP_BRAFLDRAFT_116988.3.3,,,,,,,NPC1_HUMAN,Homo sapiens (Human),adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; lysosomal transport [GO:0007041]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; positive regulation of cholesterol homeostasis [GO:2000189]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; viral entry into host cell [GO:0046718] comp26608_c0_seq1,337,38.2789,0.25037257,4,13,,4.00E-39,A0JNC4,Elongation of very long chain fatty acids protein 7 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Very-long-chain 3-oxoacyl-CoA synthase 7),Elongation of very long chain fatty acids protein 7 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Very long chain 3-ketoacyl-CoA synthase 7) (Very long chain 3-oxoacyl-CoA synthase 7),GO:0005783; GO:0005789; GO:0034626; GO:0019367; GO:0016021; GO:0016740; GO:0042761,"endoplasmic reticulum; endoplasmic reticulum membrane; fatty acid elongation, polyunsaturated fatty acid; fatty acid elongation, saturated fatty acid; integral to membrane; transferase activity; very long-chain fatty acid biosynthetic process",PF01151;,,,,,,,,,ELOV7_BOVIN,Bos taurus (Bovine),"fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]" comp26632_c0_seq1,304,45.0658,1.10508442,9,22,,6.00E-08,O43586,Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP),Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP),GO:0005826; GO:0007155; GO:0032154; GO:0005829; GO:0045087; GO:0030027; GO:0035872; GO:0048471; GO:0001725,"actomyosin contractile ring; cell adhesion; cleavage furrow; cytosol; innate immune response; lamellipodium; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; perinuclear region of cytoplasm; stress fiber",PF00611;PF14604;,,,,,,,,,PPIP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell migration [GO:0016477]; endocytosis [GO:0006897]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; signal transduction [GO:0007165] comp26633_c0_seq1,418,39.4737,0.43452101,5,36,,9.00E-11,Q2EI20,RE1-silencing transcription factor (Neural-restrictive silencer factor),RE1-silencing transcription factor (Neural-restrictive silencer factor),GO:0021785; GO:0021610; GO:0046872; GO:0010629; GO:0045879; GO:0001764; GO:0003676; GO:0005634; GO:0043065; GO:0000981; GO:0060831,branchiomotor neuron axon guidance; facial nerve morphogenesis; metal ion binding; negative regulation of gene expression; negative regulation of smoothened signaling pathway; neuron migration; nucleic acid binding; nucleus; positive regulation of apoptotic process; sequence-specific DNA binding RNA polymerase II transcription factor activity; smoothened signaling pathway involved in dorsal/ventral neural tube patterning,,,,,,,,,,REST_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"branchiomotor neuron axon guidance [GO:0021785]; facial nerve morphogenesis [GO:0021610]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron migration [GO:0001764]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; transcription, DNA-templated [GO:0006351]" comp26638_c0_seq1,348,38.2184,0.39515725,7,16,,4.00E-07,Q60542,Zinc finger E-box-binding homeobox 1 (Transcription factor 8) (TCF-8) (Zinc finger protein BZP),Zinc finger E-box-binding homeobox 1 (Transcription factor 8) (TCF-8) (Zinc finger protein BZP),GO:0070888; GO:0046872; GO:0045892; GO:0005634; GO:0045666; GO:0043565; GO:0003700; GO:0006351,"E-box binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of neuron differentiation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF05605;,,,,,,,,,ZEB1_MESAU,Mesocricetus auratus (Golden hamster),"negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neuron differentiation [GO:0045666]; transcription, DNA-templated [GO:0006351]" comp26639_c0_seq1,465,38.9247,0.70928791,13,41,,1.00E-49,P50692,Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II),Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II),GO:0005507; GO:0004129; GO:0022900; GO:0016021; GO:0005743; GO:0070469,copper ion binding; cytochrome-c oxidase activity; electron transport chain; integral to membrane; mitochondrial inner membrane; respiratory chain,PF00116;PF02790;,4.00E-80,CHOYP_COX2.2.2,,,,,,,COX2_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),electron transport chain [GO:0022900] comp26644_c0_seq1,639,45.2269,0.39927154,21,24,,4.00E-10,A2A9C3,Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_MOUSE,Mus musculus (Mouse),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp26653_c0_seq1,333,38.4384,0.08451493,4,26,,5.00E-15,Q8N6Q8,Methyltransferase-like protein 25 (EC 2.1.1.-),Methyltransferase-like protein 25 (EC 2.1.1.-),GO:0008168,methyltransferase activity,PF13679;,,,,,,,,,MET25_HUMAN,Homo sapiens (Human), comp2665_c0_seq1,205,40.4878,0.59815593,8,0,,3.00E-15,O01346,"Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)","Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)",GO:0007411; GO:0019187; GO:0007298; GO:0045165; GO:0033227; GO:0006688; GO:0016021; GO:0042248; GO:0008049; GO:0045434; GO:0030720; GO:0016325; GO:0001744; GO:0007299; GO:0046662,"axon guidance; beta-1,4-mannosyltransferase activity; border follicle cell migration; cell fate commitment; dsRNA transport; glycosphingolipid biosynthetic process; integral to membrane; maintenance of polarity of follicular epithelium; male courtship behavior; negative regulation of female receptivity, post-mating; oocyte localization involved in germarium-derived egg chamber formation; oocyte microtubule cytoskeleton organization; optic lobe placode formation; ovarian follicle cell-cell adhesion; regulation of oviposition",PF13632;,,,,,,,,,EGH_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell fate commitment [GO:0045165]; dsRNA transport [GO:0033227]; germarium-derived egg chamber formation [GO:0007293]; germ cell development [GO:0007281]; glycosphingolipid biosynthetic process [GO:0006688]; maintenance of polarity of follicular epithelium [GO:0042248]; male courtship behavior [GO:0008049]; morphogenesis of follicular epithelium [GO:0016333]; negative regulation of female receptivity, post-mating [GO:0045434]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; optic lobe placode formation [GO:0001744]; ovarian follicle cell-cell adhesion [GO:0007299]; ovarian follicle cell development [GO:0030707]; peripheral nervous system neuron development [GO:0048935]; regulation of oviposition [GO:0046662]" comp26664_c0_seq1,204,38.7255,0.79152481,0,13,,6.00E-10,Q8BQN6,Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146),Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146),GO:0003677; GO:0005737; GO:0046872; GO:0005730,DNA binding; cytoplasm; metal ion binding; nucleolus,PF00096;,,,,,,,,,OZF_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp26694_c0_seq1,328,43.2927,0.72308364,1,20,,3.00E-15,Q59228,Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A),Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A),GO:0004069; GO:0080130; GO:0009058; GO:0005737; GO:0030170,L-aspartate:2-oxoglutarate aminotransferase activity; L-phenylalanine:2-oxoglutarate aminotransferase activity; biosynthetic process; cytoplasm; pyridoxal phosphate binding,PF00155;,,,,,,,,,AAT_GEOSE,Geobacillus stearothermophilus (Bacillus stearothermophilus),biosynthetic process [GO:0009058] comp26706_c0_seq1,348,45.4023,0.44996343,7,23,,2.00E-26,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,,,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp26707_c0_seq1,558,45.6989,0.31086358,18,26,,9.00E-40,A1EC95,HEAT repeat-containing protein 6,HEAT repeat-containing protein 6,,,PF13251;,9.00E-33,CHOYP_HEAT6.1.1,,,,,,,HEAT6_RAT,Rattus norvegicus (Rat), comp2670_c0_seq1,340,43.5294,0.69773669,3,5,,1.00E-29,Q6ZQY2,Leucine-rich repeat-containing protein LOC400891,Leucine-rich repeat-containing protein 74B,,,PF13516;,1.00E-29,CHOYP_LOC100372392.4.8,,,,,,,YV012_HUMAN,Homo sapiens (Human), comp26778_c0_seq1,275,39.2727,0.58065284,0,19,,6.00E-16,Q9HAS3,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3),GO:0016021; GO:0001882; GO:0005886; GO:0015390; GO:0015864; GO:0015389; GO:0055085,integral to membrane; nucleoside binding; plasma membrane; purine-specific nucleoside:sodium symporter activity; pyrimidine nucleoside transport; pyrimidine- and adenine-specific:sodium symporter activity; transmembrane transport,PF07670;PF07662;PF01773;,,,,,,,,,S28A3_HUMAN,Homo sapiens (Human),pyrimidine nucleoside transport [GO:0015864]; retina homeostasis [GO:0001895] comp26801_c0_seq1,400,47.25,0.2285175,10,18,,3.00E-25,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp26822_c0_seq1,932,40.4506,0.81445802,39,11,,1.00E-76,O94967,WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin),WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin),GO:0005737; GO:0005874; GO:0007275,cytoplasm; microtubule; multicellular organismal development,PF12894;PF00400;,2.00E-56,CHOYP_WDR47.1.1,,,,,,,WDR47_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp26824_c0_seq1,331,44.713,0.60628749,7,11,,,,,,,,,8.00E-12,CHOYP_SMP_159780.1.2,,,,,,,,, comp26829_c0_seq1,334,38.6228,0.2415887,0,34,,9.00E-18,Q96JC1,Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p),Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p),GO:0030897; GO:0031902; GO:0005765; GO:0015031; GO:0005083,HOPS complex; late endosome membrane; lysosomal membrane; protein transport; small GTPase regulator activity,PF00780;PF10366;PF10367;,,,,,,,,,VPS39_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]" comp26845_c0_seq1,316,43.038,0.2863624,16,8,,4.00E-44,Q9W6S5,Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase),Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase),GO:0004037; GO:0000256; GO:0006144,allantoicase activity; allantoin catabolic process; purine nucleobase metabolic process,PF03561;,1.00E-35,CHOYP_NEMVEDRAFT_V1G235970.1.1,,,,,,,ALLC_XENLA,Xenopus laevis (African clawed frog),allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] comp26847_c0_seq1,317,44.795,0.88951934,18,5,,6.00E-24,Q5HYK9,Zinc finger protein 667,Zinc finger protein 667,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN667_HUMAN,Homo sapiens (Human),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp26850_c0_seq1,483,55.6936,1.01737354,0,27,,4.00E-06,Q49741,Uncharacterized protein ML0393,Uncharacterized protein ML0393,,,PF13419;,,,,,,,,,Y393_MYCLE,Mycobacterium leprae (strain TN), comp26853_c0_seq1,214,69.6262,1.2811764,0,13,,2.00E-06,Q51551,Dihydroorotase-like protein (Aspartate carbamoyltransferase 44 kDa non-catalytic chain),Dihydroorotase-like protein (Aspartate carbamoyltransferase 44 kDa non-catalytic chain),GO:0004151; GO:0009117; GO:0006221; GO:0008270,dihydroorotase activity; nucleotide metabolic process; pyrimidine nucleotide biosynthetic process; zinc ion binding,PF01979;,,,,,,,,,PYRX_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),pyrimidine nucleotide biosynthetic process [GO:0006221] comp26866_c0_seq1,475,38.9474,0.74698544,13,16,,4.00E-11,O82504,RNA-dependent RNA polymerase 2 (AtRDRP2) (EC 2.7.7.48) (Protein SILENCING MOVEMENT DEFICIENT 1) (RNA-directed RNA polymerase 2),RNA-dependent RNA polymerase 2 (AtRDRP2) (EC 2.7.7.48) (Protein SILENCING MOVEMENT DEFICIENT 1) (RNA-directed RNA polymerase 2),GO:0003723; GO:0003968; GO:0007267; GO:0050832; GO:0010495; GO:0005730; GO:0005654; GO:0030422,RNA binding; RNA-directed RNA polymerase activity; cell-cell signaling; defense response to fungus; long-distance posttranscriptional gene silencing; nucleolus; nucleoplasm; production of siRNA involved in RNA interference,PF05183;,,,,,,,,,RDR2_ARATH,Arabidopsis thaliana (Mouse-ear cress),defense response to fungus [GO:0050832]; gene silencing [GO:0016458]; long-distance posttranscriptional gene silencing [GO:0010495]; production of siRNA involved in chromatin silencing by small RNA [GO:0070919]; production of siRNA involved in RNA interference [GO:0030422] comp26870_c0_seq1,835,46.1078,0.74630849,25,33,,3.00E-28,Q08E39,Protein sprouty homolog 2 (Spry-2),Protein sprouty homolog 2 (Spry-2),GO:0048754; GO:0045165; GO:0005737; GO:0042472; GO:0060437; GO:0060425; GO:0005874; GO:0070373; GO:0043407; GO:0034261; GO:0046580; GO:0043066; GO:0008285; GO:0040037; GO:0051387; GO:0010801; GO:0070374; GO:0010628; GO:0033138; GO:0051897; GO:0043539; GO:0032587; GO:0007605,branching morphogenesis of an epithelial tube; cell fate commitment; cytoplasm; inner ear morphogenesis; lung growth; lung morphogenesis; microtubule; negative regulation of ERK1 and ERK2 cascade; negative regulation of MAP kinase activity; negative regulation of Ras GTPase activity; negative regulation of Ras protein signal transduction; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of neurotrophin TRK receptor signaling pathway; negative regulation of peptidyl-threonine phosphorylation; positive regulation of ERK1 and ERK2 cascade; positive regulation of gene expression; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase B signaling cascade; protein serine/threonine kinase activator activity; ruffle membrane; sensory perception of sound,PF05210;,,,,,,,,,SPY2_BOVIN,Bos taurus (Bovine),bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; establishment of mitotic spindle orientation [GO:0000132]; inner ear morphogenesis [GO:0042472]; lung growth [GO:0060437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of GTPase activity [GO:0034260]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cell differentiation [GO:0045595]; sensory perception of sound [GO:0007605] comp26881_c0_seq1,389,39.3316,0.55595521,7,14,,8.00E-17,Q07722,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) (Fragment)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) (Fragment)",GO:0005509; GO:0035556; GO:0016042; GO:0004435; GO:0004871,calcium ion binding; intracellular signal transduction; lipid catabolic process; phosphatidylinositol phospholipase C activity; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,,,,,,,,,PLCB4_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042] comp26891_c0_seq1,226,34.0708,0.46014414,4,8,,3.00E-10,Q640K1,Neurochondrin,Neurochondrin,GO:0005829; GO:0030425; GO:0031175; GO:0043025,cytosol; dendrite; neuron projection development; neuronal cell body,PF05536;,,,,,,,,,NCDN_XENLA,Xenopus laevis (African clawed frog),neuron projection development [GO:0031175] comp26893_c0_seq1,214,40.1869,0.34960113,2,9,,2.00E-20,Q99104,"Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle)","Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle)",GO:0005524; GO:0005794; GO:0003779; GO:0042641; GO:0042640; GO:0005509; GO:0005516; GO:0032869; GO:0005829; GO:0051643; GO:0006887; GO:0030073; GO:0032593; GO:0005882; GO:0031987; GO:0042759; GO:0042438; GO:0030318; GO:0042470; GO:0032402; GO:0000146; GO:0035371; GO:0042552; GO:0016459; GO:0043025; GO:0042476; GO:0001750; GO:0072659; GO:0031585; GO:0001726; GO:0032252; GO:0050808; GO:0007268; GO:0030050; GO:0007601,"ATP binding; Golgi apparatus; actin binding; actomyosin; anagen; calcium ion binding; calmodulin binding; cellular response to insulin stimulus; cytosol; endoplasmic reticulum localization; exocytosis; insulin secretion; insulin-responsive compartment; intermediate filament; locomotion involved in locomotory behavior; long-chain fatty acid biosynthetic process; melanin biosynthetic process; melanocyte differentiation; melanosome; melanosome transport; microfilament motor activity; microtubule plus end; myelination; myosin complex; neuronal cell body; odontogenesis; photoreceptor outer segment; protein localization to plasma membrane; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ruffle; secretory granule localization; synapse organization; synaptic transmission; vesicle transport along actin filament; visual perception",PF01843;PF00612;PF00063;,3.00E-40,CHOYP_MYO22.2.2,,,,,,,MYO5A_MOUSE,Mus musculus (Mouse),"actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; developmental pigmentation [GO:0048066]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; membrane organization [GO:0061024]; myelination [GO:0042552]; odontogenesis [GO:0042476]; pigmentation [GO:0043473]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]" comp26900_c0_seq1,221,42.9864,0.92245656,2,20,,5.00E-26,A8E0R9,Glutamate receptor-interacting protein 2 (xGRIP2) (xGRIP2.1),Glutamate receptor-interacting protein 2 (xGRIP2) (xGRIP2.1),GO:0005938; GO:0007281; GO:0008354; GO:0032019; GO:0007275; GO:0045495,cell cortex; germ cell development; germ cell migration; mitochondrial cloud; multicellular organismal development; pole plasm,PF00595;,,,,,,,,,GRIP2_XENLA,Xenopus laevis (African clawed frog),germ cell development [GO:0007281]; germ cell migration [GO:0008354]; multicellular organism development [GO:0007275] comp26906_c0_seq1,214,52.3364,0.55005998,2,16,,7.00E-19,Q9UBH6,Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor),Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor),GO:0004930; GO:0005887; GO:0001618,G-protein coupled receptor activity; integral to plasma membrane; virus receptor activity,PF03124;PF03105;,2.00E-16,CHOYP_LOC101159134.1.1,,,,,,,XPR1_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; response to virus [GO:0009615] comp26909_c0_seq1,265,42.2642,0.76953844,4,11,,6.00E-27,Q8K4S1,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)",GO:0000139; GO:0000187; GO:0005509; GO:0005829; GO:0019899; GO:0032835; GO:0005085; GO:0016042; GO:0004435; GO:0007200; GO:0005886; GO:0008277; GO:0046578; GO:0004871; GO:0007264,Golgi membrane; activation of MAPK activity; calcium ion binding; cytosol; enzyme binding; glomerulus development; guanyl-nucleotide exchange factor activity; lipid catabolic process; phosphatidylinositol phospholipase C activity; phospholipase C-activating G-protein coupled receptor signaling pathway; plasma membrane; regulation of G-protein coupled receptor protein signaling pathway; regulation of Ras protein signal transduction; signal transducer activity; small GTPase mediated signal transduction,PF00168;PF00388;PF00387;PF00788;PF00617;,6.00E-37,CHOYP_FUCTA.2.4,,,,,,,PLCE1_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; glomerulus development [GO:0032835]; lipid catabolic process [GO:0016042]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; Ras protein signal transduction [GO:0007265]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of protein kinase activity [GO:0045859]; regulation of Ras protein signal transduction [GO:0046578] comp26913_c0_seq1,335,32.2388,0.46154257,5,22,,9.00E-36,Q91X88,"Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)","Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)",GO:0000139; GO:0008375; GO:0016021; GO:0006493,Golgi membrane; acetylglucosaminyltransferase activity; integral to membrane; protein O-linked glycosylation,PF03071;,5.00E-14,CHOYP_POMGNT1.1.1,,,,,,,PMGT1_MOUSE,Mus musculus (Mouse),protein O-linked glycosylation [GO:0006493] comp26917_c0_seq1,345,36.5217,0.17594859,7,13,,9.00E-12,Q9UHC1,DNA mismatch repair protein Mlh3 (MutL protein homolog 3),DNA mismatch repair protein Mlh3 (MutL protein homolog 3),GO:0005524; GO:0016887; GO:0032390; GO:0032407; GO:0019237; GO:0005712; GO:0003682; GO:0007144; GO:0001673; GO:0007140; GO:0006298; GO:0030983; GO:0008104; GO:0007131; GO:0003696; GO:0003697; GO:0000795; GO:0007130,ATP binding; ATPase activity; MutLbeta complex; MutSalpha complex binding; centromeric DNA binding; chiasma; chromatin binding; female meiosis I; male germ cell nucleus; male meiosis; mismatch repair; mismatched DNA binding; protein localization; reciprocal meiotic recombination; satellite DNA binding; single-stranded DNA binding; synaptonemal complex; synaptonemal complex assembly,PF01119;PF08676;,,,,,,,,,MLH3_HUMAN,Homo sapiens (Human),female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] comp2695_c0_seq1,229,61.1354,0.79944276,2,2,,3.00E-44,Q6A911,Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase),Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase),GO:0044205; GO:0006207; GO:0004590,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; orotidine-5'-phosphate decarboxylase activity,PF00215;,,,,,,,,,PYRF_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205] comp26967_c1_seq1,247,41.7004,1.07318832,1,4,,2.00E-37,O75845,Lathosterol oxidase (EC 1.14.21.6) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase),Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase),GO:0000248; GO:0006695; GO:0033490; GO:0005789; GO:0006633; GO:0016021; GO:0005506; GO:0050046,C-5 sterol desaturase activity; cholesterol biosynthetic process; cholesterol biosynthetic process via lathosterol; endoplasmic reticulum membrane; fatty acid biosynthetic process; integral to membrane; iron ion binding; lathosterol oxidase activity,PF04116;,9.00E-35,CHOYP_SC5D.1.1,4.00E-18,ruditapes_c27639,,,,,SC5D_HUMAN,Homo sapiens (Human),cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] comp26991_c0_seq1,435,34.9425,1.05697528,2,29,,2.00E-15,Q8N608,Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase IV-related protein 3) (DPRP-3) (Dipeptidyl peptidase X) (DPP X) (Dipeptidyl peptidase-like protein 2) (DPL2),Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase IV-related protein 3) (DPRP-3) (Dipeptidyl peptidase X) (DPP X) (Dipeptidyl peptidase-like protein 2) (DPL2),GO:0016021; GO:0016020; GO:0006508; GO:0008236,integral to membrane; membrane; proteolysis; serine-type peptidase activity,PF00930;PF00326;,,,,,,,,,DPP10_HUMAN,Homo sapiens (Human),positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379] comp26998_c0_seq1,208,45.1923,0.6635074,4,9,,6.00E-27,P41233,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0071222; GO:0071300; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0007040; GO:0045121; GO:0002790; GO:0045335; GO:0006911; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lysosome organization; membrane raft; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,1.00E-20,CHOYP_ABCA1.1.3,,,,,,,ABCA1_MOUSE,Mus musculus (Mouse),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp27006_c0_seq1,278,44.2446,0.67139906,8,17,,7.00E-06,A7E2Y6,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),,,,,,,,,,,,HRT7A_BOVIN,Bos taurus (Bovine), comp27014_c0_seq1,814,39.9263,0.58655392,24,29,,3.00E-50,P09851,Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),GO:0051020; GO:0005099; GO:0000910; GO:0005737; GO:0009790; GO:0031235; GO:0046580; GO:0001953; GO:0043524; GO:0005543; GO:0005102; GO:0030833; GO:0007165; GO:0001570,GTPase binding; Ras GTPase activator activity; cytokinesis; cytoplasm; embryo development; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; negative regulation of cell-matrix adhesion; negative regulation of neuron apoptotic process; phospholipid binding; receptor binding; regulation of actin filament polymerization; signal transduction; vasculogenesis,PF00168;PF00169;PF00616;PF00017;PF00018;,,,,,,,,,RASA1_BOVIN,Bos taurus (Bovine),embryo development [GO:0009790]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] comp27036_c0_seq1,272,36.7647,0.87923894,6,14,,9.00E-49,A2VD83,Mannose-1-phosphate guanyltransferase beta-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B-B) (GTP-mannose-1-phosphate guanylyltransferase beta-B),Mannose-1-phosphate guanyltransferase beta-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B-B) (GTP-mannose-1-phosphate guanylyltransferase beta-B),GO:0009298; GO:0005525; GO:0004475,GDP-mannose biosynthetic process; GTP binding; mannose-1-phosphate guanylyltransferase activity,PF00132;PF00483;,1.00E-39,CHOYP_NEMVEDRAFT_V1G162365.1.1,,,,,,,GMPBB_XENLA,Xenopus laevis (African clawed frog),GDP-mannose biosynthetic process [GO:0009298] comp27042_c0_seq1,225,61.3333,1.06241415,0,12,,8.00E-32,A7MM56,Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase),Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase),GO:0006464; GO:0008113,cellular protein modification process; peptide-methionine (S)-S-oxide reductase activity,PF01625;,,,,,,,,,MSRA_CROS8,Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii),cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp27074_c0_seq1,255,36.4706,0.39958991,5,13,,,,,,,,,,,2.00E-15,ruditapes2_lrc4444,,,,,,, comp27084_c0_seq1,454,45.815,0.93595592,5,27,,2.00E-36,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp27090_c0_seq1,222,39.6396,0.58074095,5,11,,1.00E-07,Q9WU60,Attractin (Protein mahogany),Attractin (Protein mahogany),GO:0030246; GO:0021549; GO:0005737; GO:0005615; GO:0006954; GO:0016021; GO:0042552; GO:0043473; GO:0005886; GO:0004872; GO:0040014; GO:0006979,carbohydrate binding; cerebellum development; cytoplasm; extracellular space; inflammatory response; integral to membrane; myelination; pigmentation; plasma membrane; receptor activity; regulation of multicellular organism growth; response to oxidative stress,PF00431;PF01344;PF00059;PF01437;,,,,,,,,,ATRN_MOUSE,Mus musculus (Mouse),cerebellum development [GO:0021549]; inflammatory response [GO:0006954]; myelination [GO:0042552]; pigmentation [GO:0043473]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979] comp27091_c0_seq1,292,44.5205,0.13899594,0,26,,8.00E-24,Q11073,Uncharacterized protein B0416.5,Uncharacterized protein B0416.5,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,YT45_CAEEL,Caenorhabditis elegans,transmembrane transport [GO:0055085] comp27117_c0_seq1,412,41.9903,0.6704585,13,14,,9.00E-48,P45447,Ecdysone-induced protein 78C (DR-78) (Nuclear receptor subfamily 1 group E member 1),Ecdysone-induced protein 78C (DR-78) (Nuclear receptor subfamily 1 group E member 1),GO:0004879; GO:0005634; GO:0043565; GO:0003707; GO:0008270,ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,2.00E-52,CHOYP_LOC100377194.2.2,,,,,,,E78C_DROME,Drosophila melanogaster (Fruit fly),"instar larval or pupal development [GO:0002165]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]" comp27130_c0_seq1,287,44.9477,0.76375083,3,11,,4.00E-19,P54276,DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS-alpha 160 kDa subunit) (p160),DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160),GO:0043531; GO:0005524; GO:0008094; GO:0032301; GO:0003682; GO:0003684; GO:0008340; GO:0000400; GO:0032137; GO:0008630; GO:0045190; GO:0000287; GO:0043570; GO:0000710; GO:0035064; GO:0045910; GO:0000790; GO:0032357; GO:0051096; GO:0007131; GO:0009411; GO:0032138; GO:0032142; GO:0032143; GO:0016446,ADP binding; ATP binding; DNA-dependent ATPase activity; MutSalpha complex; chromatin binding; damaged DNA binding; determination of adult lifespan; four-way junction DNA binding; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; magnesium ion binding; maintenance of DNA repeat elements; meiotic mismatch repair; methylated histone residue binding; negative regulation of DNA recombination; nuclear chromatin; oxidized purine DNA binding; positive regulation of helicase activity; reciprocal meiotic recombination; response to UV; single base insertion or deletion binding; single guanine insertion binding; single thymine insertion binding; somatic hypermutation of immunoglobulin genes,PF01624;PF05188;PF05192;PF05190;PF00488;PF00855;,,,,,,,,,MSH6_MOUSE,Mus musculus (Mouse),determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching [GO:0045830]; reciprocal meiotic recombination [GO:0007131]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447] comp27135_c0_seq2,502,42.2311,0.45254341,6,16,,5.00E-22,Q80TY5,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp27146_c0_seq1,525,46.2857,0.85528766,6,25,,3.00E-52,P10351,Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus),Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus),GO:0051537; GO:0008762; GO:0006525; GO:0048072; GO:0008340; GO:0009055; GO:0050660; GO:0006650; GO:0005506; GO:0005875; GO:0043546; GO:0005777; GO:0006206; GO:0006568; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; arginine metabolic process; compound eye pigmentation; determination of adult lifespan; electron carrier activity; flavin adenine dinucleotide binding; glycerophospholipid metabolic process; iron ion binding; microtubule associated complex; molybdopterin cofactor binding; peroxisome; pyrimidine nucleobase metabolic process; tryptophan metabolic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,7.00E-15,CHOYP_XDH.1.3,,,,,,,XDH_DROME,Drosophila melanogaster (Fruit fly),arginine metabolic process [GO:0006525]; compound eye pigmentation [GO:0048072]; determination of adult lifespan [GO:0008340]; glycerophospholipid metabolic process [GO:0006650]; purine nucleobase metabolic process [GO:0006144]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ethanol [GO:0045471]; tryptophan metabolic process [GO:0006568]; xanthine catabolic process [GO:0009115] comp27178_c0_seq1,372,44.086,1.33136001,4,28,,8.00E-21,Q8BFV3,Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48),Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48),GO:0017017; GO:0001706; GO:0005654; GO:0035335; GO:0004725,MAP kinase tyrosine/serine/threonine phosphatase activity; endoderm formation; nucleoplasm; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00782;PF00581;,,,,,,,,,DUS4_MOUSE,Mus musculus (Mouse),dephosphorylation [GO:0016311]; endoderm formation [GO:0001706]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335] comp27183_c0_seq2,323,43.6533,0.78419469,13,1,,2.00E-24,Q0P4M4,Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),GO:0005829; GO:0004181; GO:0006508; GO:0008270,cytosol; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,1.00E-40,CHOYP_LOC580601.4.5,,,,,,,CBPC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein side chain deglutamylation [GO:0035610] comp27199_c0_seq1,317,45.7413,0.24293595,8,9,,1.00E-21,Q6PDH0,Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha),GO:0005543,phospholipid binding,PF00169;,1.00E-14,CHOYP_PHLB1.1.1,,,,,,,PHLB1_MOUSE,Mus musculus (Mouse),positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507] comp27200_c0_seq1,253,42.2925,1.17094028,4,11,,9.00E-33,P91119,"Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)","Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)",GO:0004114; GO:0008152; GO:0046872; GO:0007165,"3',5'-cyclic-nucleotide phosphodiesterase activity; metabolic process; metal ion binding; signal transduction",PF01590;PF00233;,2.00E-30,CHOYP_TRIADDRAFT_21752.1.1,,,,,,,PDE5_CAEEL,Caenorhabditis elegans,chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP biosynthetic process [GO:0030827]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542] comp27207_c0_seq1,260,45,0.76272315,7,8,,4.00E-22,E1BD52,Transmembrane protein 245,Transmembrane protein 245,GO:0016021,integral to membrane,PF01594;,2.00E-23,CHOYP_BRAFLDRAFT_85004.1.1,,,,,,,TM245_BOVIN,Bos taurus (Bovine), comp27211_c0_seq1,280,40,0.5734767,11,4,,9.00E-11,Q5TZ51,Protein Mpv17,Protein Mpv17,GO:0016021; GO:0005743,integral to membrane; mitochondrial inner membrane,PF04117;,,,2.00E-36,ruditapes_c8324,,,,,MPV17_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp27232_c0_seq1,245,44.4898,0.66939891,0,17,,1.00E-24,P31650,Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11),Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11),GO:0007420; GO:0042995; GO:0005737; GO:0005332; GO:0005887; GO:0042165; GO:0005328; GO:0042493,brain development; cell projection; cytoplasm; gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter binding; neurotransmitter:sodium symporter activity; response to drug,PF00209;,,,,,,,,,S6A11_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836]; response to drug [GO:0042493] comp27236_c0_seq1,204,45.098,1.16314852,4,8,,1.00E-07,O01367,Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F),Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F),GO:0007475; GO:0008366; GO:0007155; GO:0005737; GO:0030718; GO:0008347; GO:0003730; GO:0008078; GO:0016203; GO:0007521; GO:0005634; GO:0007438; GO:0000381; GO:0008016; GO:0045214; GO:0007525; GO:0007284,"apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon ensheathment; cell adhesion; cytoplasm; germ-line stem cell maintenance; glial cell migration; mRNA 3'-UTR binding; mesodermal cell migration; muscle attachment; muscle cell fate determination; nucleus; oenocyte development; regulation of alternative mRNA splicing, via spliceosome; regulation of heart contraction; sarcomere organization; somatic muscle development; spermatogonial cell division",PF00013;PF16544;,5.00E-18,CHOYP_HOW.2.5,,,,,,,HOW_DROME,Drosophila melanogaster (Fruit fly),"apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]" comp27245_c0_seq1,251,62.9482,1.01992877,0,20,,7.00E-20,Q73SP5,3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III),3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III),GO:0004315; GO:0033818; GO:0005737; GO:0006633,3-oxoacyl-[acyl-carrier-protein] synthase activity; beta-ketoacyl-acyl-carrier-protein synthase III activity; cytoplasm; fatty acid biosynthetic process,PF08545;PF08541;,,,,,,,,,FABH_MYCPA,Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10),fatty acid biosynthetic process [GO:0006633] comp27246_c0_seq1,203,33.0049,0.72858911,4,13,,6.00E-18,Q08B22,"GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)","GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)",GO:0004377; GO:0009058; GO:0016021,"GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity; biosynthetic process; integral to membrane",PF15924;PF00534;,,,,,,,,,ALG11_XENLA,Xenopus laevis (African clawed frog), comp27258_c0_seq1,232,56.8966,1.13607869,0,14,,1.00E-07,Q6A761,Thymidylate synthase (TS) (TSase) (EC 2.1.1.45),Thymidylate synthase (TS) (TSase) (EC 2.1.1.45),GO:0005737; GO:0006231; GO:0006235; GO:0004799,cytoplasm; dTMP biosynthetic process; dTTP biosynthetic process; thymidylate synthase activity,PF00303;,,,,,,,,,TYSY_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235] comp27268_c0_seq1,278,45.6835,0.36788451,2,13,,4.00E-29,Q9NUB1,"Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)","Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)",GO:0016208; GO:0005524; GO:0019413; GO:0003987; GO:0006085; GO:0019427; GO:0006069; GO:0005759; GO:0019542; GO:0006805,AMP binding; ATP binding; acetate biosynthetic process; acetate-CoA ligase activity; acetyl-CoA biosynthetic process; acetyl-CoA biosynthetic process from acetate; ethanol oxidation; mitochondrial matrix; propionate biosynthetic process; xenobiotic metabolic process,PF16177;PF00501;PF13193;,1.00E-27,CHOYP_BRAFLDRAFT_59014.1.1,,,,,,,ACS2L_HUMAN,Homo sapiens (Human),acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; ethanol oxidation [GO:0006069]; propionate biosynthetic process [GO:0019542] comp2726_c0_seq1,519,38.5356,0.36403776,15,0,,1.00E-19,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp27271_c0_seq1,623,44.3018,0.49152046,17,11,,2.00E-25,Q80XK6,Autophagy-related protein 2 homolog B,Autophagy-related protein 2 homolog B,GO:0006914; GO:0005811; GO:0034045,autophagy; lipid particle; pre-autophagosomal structure membrane,PF13329;PF09333;PF12624;,,,,,,,,,ATG2B_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp27317_c0_seq1,225,42.6667,0.4066657,7,11,,5.00E-21,Q5RKI3,DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-),DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-),GO:0003677; GO:0006260; GO:0003887; GO:0016829; GO:0046872; GO:0006289; GO:0005634,DNA binding; DNA replication; DNA-directed DNA polymerase activity; lyase activity; metal ion binding; nucleotide-excision repair; nucleus,PF14792;PF14791;PF10391;PF14716;,1.00E-26,CHOYP_BRAFLDRAFT_235602.1.1,,,,,,,DPOLL_RAT,Rattus norvegicus (Rat),DNA replication [GO:0006260]; nucleotide-excision repair [GO:0006289] comp27338_c0_seq1,442,41.629,0.75276511,9,19,,4.00E-09,Q9ERK0,Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-associated protein kinase) (PKC-regulated protein kinase),Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-associated protein kinase) (PKC-regulated protein kinase),GO:0005524; GO:0005737; GO:0016020; GO:0004674,ATP binding; cytoplasm; membrane; protein serine/threonine kinase activity,PF12796;PF00069;,,,,,,,,,RIPK4_MOUSE,Mus musculus (Mouse),morphogenesis of an epithelium [GO:0002009]; positive regulation of NF-kappaB transcription factor activity [GO:0051092] comp2733_c0_seq1,236,45.7627,0.7406383,2,4,,2.00E-19,Q5RE34,Regulator of telomere elongation helicase 1 (EC 3.6.4.12),Regulator of telomere elongation helicase 1 (EC 3.6.4.12),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0046872; GO:0005634; GO:0010569; GO:0000723,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; metal ion binding; nucleus; regulation of double-strand break repair via homologous recombination; telomere maintenance",PF06733;PF13307;,8.00E-16,CHOYP_RTEL1.1.1,,,,,,,RTEL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723] comp27348_c0_seq1,296,49.6622,0.60952188,6,0,,5.00E-28,P32138,Alpha-glucosidase YihQ (EC 3.2.1.20),Sulfoquinovosidase (SQase) (EC 3.2.1.-),GO:0030246; GO:0005975; GO:0032450,carbohydrate binding; carbohydrate metabolic process; maltose alpha-glucosidase activity,PF01055;,,,,,,,,,YIHQ_ECOLI,Escherichia coli (strain K12),carbohydrate metabolic process [GO:0005975] comp27350_c0_seq1,814,45.086,0.49146791,13,33,,9.00E-72,O60706,ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2),ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2),GO:0005524; GO:0006200; GO:0008282; GO:0042626; GO:0051607; GO:0005267; GO:0015459; GO:0010107; GO:0042383; GO:0030017; GO:0008281; GO:0007268; GO:0005215; GO:0008076,"ATP binding; ATP catabolic process; ATP-sensitive potassium channel complex; ATPase activity, coupled to transmembrane movement of substances; defense response to virus; potassium channel activity; potassium channel regulator activity; potassium ion import; sarcolemma; sarcomere; sulfonylurea receptor activity; synaptic transmission; transporter activity; voltage-gated potassium channel complex",PF00664;PF00005;,4.00E-45,CHOYP_BRAFLDRAFT_118957.1.1,,,,,,,ABCC9_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; potassium ion import [GO:0010107]; potassium ion transport [GO:0006813]; regulation of cardiac conduction [GO:1903779]; transmembrane transport [GO:0055085] comp27358_c0_seq1,280,50,0.63082437,6,12,,8.00E-28,Q5T4F7,Secreted frizzled-related protein 5 (sFRP-5) (Frizzled-related protein 1b) (FRP-1b) (Secreted apoptosis-related protein 3) (SARP-3),Secreted frizzled-related protein 5 (sFRP-5) (Frizzled-related protein 1b) (FRP-1b) (Secreted apoptosis-related protein 3) (SARP-3),GO:0030165; GO:0042813; GO:0017147; GO:0009653; GO:0006915; GO:0007420; GO:0030154; GO:0060028; GO:0005737; GO:0048546; GO:0009790; GO:0007163; GO:0005615; GO:0008406; GO:0043508; GO:2000057; GO:0090090; GO:0035414; GO:0008285; GO:2000041; GO:0051898; GO:0043433; GO:0090179; GO:0005886; GO:0036342; GO:0001944; GO:0007601,PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; anatomical structure morphogenesis; apoptotic process; brain development; cell differentiation; convergent extension involved in axis elongation; cytoplasm; digestive tract morphogenesis; embryo development; establishment or maintenance of cell polarity; extracellular space; gonad development; negative regulation of JUN kinase activity; negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of catenin import into nucleus; negative regulation of cell proliferation; negative regulation of planar cell polarity pathway involved in axis elongation; negative regulation of protein kinase B signaling cascade; negative regulation of sequence-specific DNA binding transcription factor activity; planar cell polarity pathway involved in neural tube closure; plasma membrane; post-anal tail morphogenesis; vasculature development; visual perception,PF01392;PF01759;,,,,,,,,,SFRP5_HUMAN,Homo sapiens (Human),anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; establishment or maintenance of cell polarity [GO:0007163]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of catenin import into nucleus [GO:0035414]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis [GO:2000057]; non-canonical Wnt signaling pathway [GO:0035567]; signal transduction [GO:0007165]; visual perception [GO:0007601] comp27372_c0_seq1,245,42.0408,0.56552666,6,10,,3.00E-08,D3ZQG6,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_RAT,Rattus norvegicus (Rat),regulation of neuron apoptotic process [GO:0043523] comp27380_c0_seq1,446,42.6009,0.59494532,10,26,,1.00E-38,Q5R4G2,Platelet-activating factor acetylhydrolase IB subunit beta (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta),Platelet-activating factor acetylhydrolase IB subunit beta (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta),GO:0003847; GO:0005737; GO:0016042,1-alkyl-2-acetylglycerophosphocholine esterase activity; cytoplasm; lipid catabolic process,PF13472;,,,,,,,,,PA1B2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),lipid catabolic process [GO:0016042] comp27387_c0_seq1,227,44.0529,0.829107,0,0,,5.00E-14,Q8IUM7,Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (Class E basic helix-loop-helix protein 79) (bHLHe79) (HLH-PAS transcription factor NXF) (PAS domain-containing protein 10),Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (Class E basic helix-loop-helix protein 79) (bHLHe79) (HLH-PAS transcription factor NXF) (PAS domain-containing protein 10),GO:0003677; GO:0005634; GO:0045944; GO:0004871; GO:0005667; GO:0006351,"DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF08447;,,,,,,,,,NPAS4_HUMAN,Homo sapiens (Human),cellular response to corticosterone stimulus [GO:0071386]; inhibitory postsynaptic potential [GO:0060080]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp27387_c0_seq2,244,47.9508,0.7163863,4,0,,,,,,,,,1.00E-25,CHOYP_BRAFLDRAFT_121518.1.1,,,,,,,,, comp2738_c0_seq1,282,41.4894,0.41350608,8,0,,5.00E-11,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp2742_c0_seq1,248,50,0.51943478,11,0,,2.00E-52,Q9WVL6,Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3),Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3),GO:0001888; GO:0015012; GO:0016021; GO:0031227; GO:0046872,glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; metal ion binding,PF03016;PF09258;,8.00E-48,CHOYP_EXTL3.1.1,,,,,,,EXTL3_MOUSE,Mus musculus (Mouse),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] comp27474_c0_seq1,455,37.8022,0.49431133,14,22,,1.00E-52,Q96QU8,Exportin-6 (Exp6) (Ran-binding protein 20),Exportin-6 (Exp6) (Ran-binding protein 20),GO:0005737; GO:0005730; GO:0005886; GO:0006611; GO:0008565,cytoplasm; nucleolus; plasma membrane; protein export from nucleus; protein transporter activity,PF03810;PF08389;,1.00E-48,CHOYP_XPO6.1.1,,,,,,,XPO6_HUMAN,Homo sapiens (Human),protein export from nucleus [GO:0006611] comp27507_c0_seq1,479,39.2484,0.74712969,12,26,,4.00E-20,Q92551,Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1),Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1),GO:0005524; GO:0005829; GO:0052723; GO:0052724; GO:0000832; GO:0043647; GO:0008440; GO:0005730; GO:0005654; GO:0046854,"ATP binding; cytosol; inositol hexakisphosphate 1-kinase activity; inositol hexakisphosphate 3-kinase activity; inositol hexakisphosphate 5-kinase activity; inositol phosphate metabolic process; inositol-1,4,5-trisphosphate 3-kinase activity; nucleolus; nucleoplasm; phosphatidylinositol phosphorylation",PF03770;,,,,,,,,,IP6K1_HUMAN,Homo sapiens (Human),inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol phosphorylation [GO:0046854] comp27522_c0_seq1,208,43.2692,0.11611379,0,19,,7.00E-34,Q4JIJ3,Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),GO:0031419; GO:0005737; GO:0008898; GO:0008705; GO:0042558; GO:0008270,cobalamin binding; cytoplasm; homocysteine S-methyltransferase activity; methionine synthase activity; pteridine-containing compound metabolic process; zinc ion binding,PF02310;PF02607;PF02965;PF00809;PF02574;,1.00E-26,CHOYP_METH.1.1,,,,,,,METH_BOVIN,Bos taurus (Bovine),pteridine-containing compound metabolic process [GO:0042558] comp27527_c0_seq1,330,46.9697,0.27694364,4,14,,6.00E-09,Q9FGY1,Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55),Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55),GO:0046556; GO:0048046; GO:0005975; GO:0009505; GO:0005578; GO:0010214,alpha-N-arabinofuranosidase activity; apoplast; carbohydrate metabolic process; plant-type cell wall; proteinaceous extracellular matrix; seed coat development,PF14310;PF00933;PF01915;,,,,,,,,,BXL1_ARATH,Arabidopsis thaliana (Mouse-ear cress),arabinan catabolic process [GO:0031222]; seed coat development [GO:0010214]; xylan catabolic process [GO:0045493] comp27533_c0_seq1,242,47.1074,0.67334894,5,16,,2.00E-11,Q3T1L0,Aldehyde dehydrogenase family 16 member A1,Aldehyde dehydrogenase family 16 member A1,GO:0016620,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",PF00171;,,,,,,,,,A16A1_RAT,Rattus norvegicus (Rat), comp27540_c0_seq1,242,39.2562,0.33136929,0,20,,4.00E-11,Q0JL46,Neutral ceramidase (N-CDase) (NCDase) (OsCDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase),Neutral ceramidase (N-CDase) (NCDase) (OsCDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase),GO:0005794; GO:0017040; GO:0005783; GO:0005576,Golgi apparatus; ceramidase activity; endoplasmic reticulum; extracellular region,PF04734;PF17048;,,,,,,,,,NCASE_ORYSJ,Oryza sativa subsp. japonica (Rice), comp27577_c0_seq1,368,41.0326,0.4533203,13,15,,1.00E-10,Q9QZ48,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein),GO:0003677; GO:0030154; GO:0035035; GO:0046872; GO:0007275; GO:0045892; GO:0005634; GO:0045670; GO:0003700; GO:0006351,"DNA binding; cell differentiation; histone acetyltransferase binding; metal ion binding; multicellular organismal development; negative regulation of transcription, DNA-dependent; nucleus; regulation of osteoclast differentiation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_RAT,Rattus norvegicus (Rat),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp27582_c0_seq1,217,60.3687,1.33430329,0,13,,5.00E-30,Q6A9H8,GTPase obg (GTP-binding protein obg),GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0000287,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; magnesium ion binding,PF09269;PF01018;PF01926;,,,,,,,,,OBG_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),ribosome biogenesis [GO:0042254] comp27596_c0_seq1,241,41.0788,0.30000517,6,17,,2.00E-12,Q25BN1,Endoribonuclease Dicer (EC 3.1.26.-),Endoribonuclease Dicer (EC 3.1.26.3),GO:0005524; GO:0008026; GO:0016442; GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0031054; GO:0030422; GO:0004525; GO:0030423,ATP binding; ATP-dependent helicase activity; RISC complex; RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; pre-miRNA processing; production of siRNA involved in RNA interference; ribonuclease III activity; targeting of mRNA for destruction involved in RNA interference,PF00270;PF03368;PF00271;PF02170;PF00636;,,,,,,,,,DICER_CHICK,Gallus gallus (Chicken),apoptotic DNA fragmentation [GO:0006309]; pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423] comp27626_c0_seq1,243,42.3868,0.85117721,0,29,,7.00E-09,Q96AY4,Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio),GO:0051301; GO:0005737; GO:0005815; GO:0030496; GO:0007067; GO:0000922,cell division; cytoplasm; microtubule organizing center; midbody; mitosis; spindle pole,PF12770;PF13176;PF13181;,3.00E-27,CHOYP_TTC28.1.1,,,,,,,TTC28_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346] comp27629_c1_seq1,368,39.9457,1.39456812,4,22,,8.00E-52,Q8BKG4,Frizzled-10 (Fz-10) (CD antigen CD350),Frizzled-10 (Fz-10) (CD antigen CD350),GO:0004930; GO:0030165; GO:0042813; GO:0007420; GO:0060070; GO:0042995; GO:0009986; GO:0005737; GO:0009790; GO:0008406; GO:0016021; GO:0034259; GO:0038031; GO:0005886; GO:0043507; GO:0032855; GO:0032956; GO:0006357; GO:0001944,G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; brain development; canonical Wnt receptor signaling pathway; cell projection; cell surface; cytoplasm; embryo development; gonad development; integral to membrane; negative regulation of Rho GTPase activity; non-canonical Wnt receptor signaling pathway via JNK cascade; plasma membrane; positive regulation of JUN kinase activity; positive regulation of Rac GTPase activity; regulation of actin cytoskeleton organization; regulation of transcription from RNA polymerase II promoter; vasculature development,PF01534;PF01392;,,,,,,,,,FZD10_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; multicellular organism development [GO:0007275]; negative regulation of GTPase activity [GO:0034260]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; regulation of actin cytoskeleton organization [GO:0032956]; Wnt signaling pathway [GO:0016055] comp27645_c1_seq1,320,50.3125,0.99166863,1,27,,1.00E-19,Q95ZJ1,Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5),GO:0000139; GO:0016021; GO:0004653; GO:0018243,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation via threonine,PF00535;PF00652;,,,,,,,,,GALT5_CAEEL,Caenorhabditis elegans,protein O-linked glycosylation via threonine [GO:0018243] comp2764_c0_seq1,241,45.2282,0.40823915,3,0,,,,,,,,,6.00E-37,CHOYP_CAHD1.4.6,,,,,,,,, comp2764_c1_seq1,301,43.5216,0.28237806,4,6,,5.00E-43,Q5VU97,VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1),VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1),GO:0006816; GO:0016021,calcium ion transport; integral to membrane,PF00092;PF08399;,,,,,,,,,CAHD1_HUMAN,Homo sapiens (Human),calcium ion transport [GO:0006816] comp27657_c0_seq1,377,46.4191,0.87026614,17,6,,5.00E-21,Q9NRA2,Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),GO:0006865; GO:0030054; GO:0005887; GO:0005765; GO:0015136; GO:0015739; GO:0005351; GO:0030672,amino acid transport; cell junction; integral to plasma membrane; lysosomal membrane; sialic acid transmembrane transporter activity; sialic acid transport; sugar:hydrogen symporter activity; synaptic vesicle membrane,PF07690;,,,,,,,,,S17A5_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739] comp27668_c0_seq2,524,43.3206,0.58139747,15,9,,2.00E-62,A5D794,GTPase-activating protein and VPS9 domain-containing protein 1,GTPase-activating protein and VPS9 domain-containing protein 1,GO:0032794; GO:0005096; GO:0005829; GO:0006897; GO:0005768; GO:0005085; GO:0016020; GO:0043547; GO:0051223; GO:0051056; GO:0007165,GTPase activating protein binding; GTPase activator activity; cytosol; endocytosis; endosome; guanyl-nucleotide exchange factor activity; membrane; positive regulation of GTPase activity; regulation of protein transport; regulation of small GTPase mediated signal transduction; signal transduction,PF00616;PF02204;,3.00E-38,CHOYP_LOC100866049.1.1,,,,,,,GAPD1_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165] comp27675_c0_seq2,312,38.7821,0.76968004,2,3,,5.00E-07,O15033,Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-),Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-),GO:0006915; GO:0005829; GO:0016021; GO:0043066; GO:0005634; GO:0042787; GO:0004842,apoptotic process; cytosol; integral to membrane; negative regulation of apoptotic process; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00630;PF00632;,3.00E-11,CHOYP_CG4238.1.1,,,,,,,K0317_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp27679_c0_seq1,708,43.3616,0.3916802,23,34,,2.00E-25,Q68EA5,Zinc finger protein 57 (Zinc finger protein 424),Zinc finger protein 57 (Zinc finger protein 424),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,1.00E-18,ruditapes_c25897,,,,,ZNF57_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp27694_c0_seq1,203,40.3941,0.73515297,0,11,,9.00E-06,E0W481,"1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD)","1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD)",GO:0019509; GO:0010309; GO:0005737; GO:0005506; GO:0005634,L-methionine salvage from methylthioadenosine; acireductone dioxygenase [iron(II)-requiring] activity; cytoplasm; iron ion binding; nucleus,PF03079;,,,,,,,,,MTND_PEDHC,Pediculus humanus subsp. corporis (Body louse),L-methionine biosynthetic process from methylthioadenosine [GO:0019509] comp27708_c0_seq1,428,41.1215,0.95671518,3,28,,2.00E-19,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,,,,,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp27725_c0_seq1,645,48.3721,0.85115698,24,17,,5.00E-40,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp27762_c0_seq1,206,38.3495,0.61334779,2,4,,2.00E-06,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp27762_c1_seq1,221,41.1765,0.53624286,1,13,,5.00E-11,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp27773_c0_seq1,250,40.8,0.51079368,6,12,,1.00E-24,A2A8U2,Transmembrane protein 201 (Spindle-associated membrane protein 1),Transmembrane protein 201 (Spindle-associated membrane protein 1),GO:0051015; GO:0010761; GO:0016021; GO:0005521; GO:0005637; GO:0031965; GO:0007097,actin filament binding; fibroblast migration; integral to membrane; lamin binding; nuclear inner membrane; nuclear membrane; nuclear migration,PF10476;PF09779;,6.00E-18,CHOYP_LOC100720883.1.1,,,,,,,TM201_MOUSE,Mus musculus (Mouse),fibroblast migration [GO:0010761]; nuclear migration [GO:0007097]; nuclear migration along microtubule [GO:0030473] comp27777_c0_seq1,205,46.3415,0.66027212,4,11,,7.00E-17,P22304,Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain],Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain],GO:0005975; GO:0030207; GO:0004423; GO:0043202; GO:0046872,carbohydrate metabolic process; chondroitin sulfate catabolic process; iduronate-2-sulfatase activity; lysosomal lumen; metal ion binding,PF00884;,,,,,,,,,IDS_HUMAN,Homo sapiens (Human),chondroitin sulfate catabolic process [GO:0030207]; glycosaminoglycan catabolic process [GO:0006027] comp2777_c0_seq1,282,40.4255,1.04654629,8,4,,4.00E-07,Q90773,Protein CEPU-1,Protein CEPU-1,GO:0031225; GO:0007155; GO:0005886,anchored to membrane; cell adhesion; plasma membrane,PF07679;PF00047;,,,,,,,,,CEPU1_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155] comp27785_c0_seq1,536,42.5373,0.66625542,18,26,,6.00E-74,O00329,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)",GO:0016303; GO:0035005; GO:0005524; GO:0042113; GO:0035754; GO:0001782; GO:0050853; GO:0038095; GO:0010818; GO:0030217; GO:0050852; GO:0002250; GO:0001816; GO:0007173; GO:0008543; GO:0006954; GO:0045087; GO:0002551; GO:0043303; GO:0060374; GO:0035747; GO:0001779; GO:0048011; GO:0030593; GO:0072672; GO:0014065; GO:0005942; GO:0046934; GO:0005886; GO:0006468; GO:0002679; GO:0044281,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; B cell activation; B cell chemotaxis; B cell homeostasis; B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; T cell chemotaxis; T cell differentiation; T cell receptor signaling pathway; adaptive immune response; cytokine production; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; inflammatory response; innate immune response; mast cell chemotaxis; mast cell degranulation; mast cell differentiation; natural killer cell chemotaxis; natural killer cell differentiation; neurotrophin TRK receptor signaling pathway; neutrophil chemotaxis; neutrophil extravasation; phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; plasma membrane; protein phosphorylation; respiratory burst involved in defense response; small molecule metabolic process",PF00454;PF00792;PF02192;PF00794;PF00613;,6.00E-60,CHOYP_PK3CD.1.1,,,,,,,PK3CD_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell chemotaxis [GO:0035754]; B cell receptor signaling pathway [GO:0050853]; cytokine production [GO:0001816]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell chemotaxis [GO:0002551]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; natural killer cell activation [GO:0030101]; natural killer cell chemotaxis [GO:0035747]; natural killer cell differentiation [GO:0001779]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; respiratory burst involved in defense response [GO:0002679]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] comp27806_c0_seq1,222,41.8919,1.34091527,4,8,,1.00E-13,Q9BPW9,Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE),Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE),GO:0042904; GO:0004022; GO:0008209; GO:0030855; GO:0030176; GO:0042448; GO:0016854; GO:0004745; GO:0042572; GO:0047035,9-cis-retinoic acid biosynthetic process; alcohol dehydrogenase (NAD) activity; androgen metabolic process; epithelial cell differentiation; integral to endoplasmic reticulum membrane; progesterone metabolic process; racemase and epimerase activity; retinol dehydrogenase activity; retinol metabolic process; testosterone dehydrogenase (NAD+) activity,PF00106;,,,,,,,,,DHRS9_HUMAN,Homo sapiens (Human),9-cis-retinoic acid biosynthetic process [GO:0042904]; androgen metabolic process [GO:0008209]; epithelial cell differentiation [GO:0030855]; progesterone metabolic process [GO:0042448]; retinol metabolic process [GO:0042572] comp27810_c0_seq1,428,57.7103,0.9282112,9,15,,2.00E-09,P18777,Anaerobic dimethyl sulfoxide reductase chain C (DMSO reductase anchor subunit),Anaerobic dimethyl sulfoxide reductase chain C (DMSO reductase anchor subunit),GO:0019645; GO:0009061; GO:0009390; GO:0016021; GO:0016491; GO:0005886,anaerobic electron transport chain; anaerobic respiration; dimethyl sulfoxide reductase complex; integral to membrane; oxidoreductase activity; plasma membrane,PF04976;,,,,,,,,,DMSC_ECOLI,Escherichia coli (strain K12),anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061] comp27823_c0_seq1,262,40.458,0.57845417,10,19,,2.00E-17,Q5ZKS8,UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-),UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-),GO:0016209; GO:0072358; GO:0005783; GO:0005789; GO:0001885; GO:0030173; GO:0009234; GO:0005739; GO:0004659; GO:0006744; GO:0042371,antioxidant activity; cardiovascular system development; endoplasmic reticulum; endoplasmic reticulum membrane; endothelial cell development; integral to Golgi membrane; menaquinone biosynthetic process; mitochondrion; prenyltransferase activity; ubiquinone biosynthetic process; vitamin K biosynthetic process,PF01040;,8.00E-17,CHOYP_UBIA1.1.1,,,,,,,UBIA1_CHICK,Gallus gallus (Chicken),cardiovascular system development [GO:0072358]; endothelial cell development [GO:0001885]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]; vitamin K biosynthetic process [GO:0042371] comp27858_c0_seq1,294,40.4762,0.16695156,13,8,,5.00E-23,Q7TPQ3,"E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)","E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)",GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0016874; GO:0000786; GO:0006334; GO:0005634; GO:0016567; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; ligase activity; nucleosome; nucleosome assembly; nucleus; protein ubiquitination; zinc ion binding,PF00271;PF00538;PF00176;,,,,,,,,,SHPRH_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] comp27868_c0_seq1,228,51.7544,0.65805864,2,16,,2.00E-27,Q8MVS5,Polypeptide N-acetylgalactosaminyltransferase 35A (EC 2.4.1.41) (Protein l(2)35Aa) (Protein-UDP acetylgalactosaminyltransferase 35A) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 35A) (pp-GaNTase 35A) (dGalNAc-T1),Polypeptide N-acetylgalactosaminyltransferase 35A (EC 2.4.1.41) (Protein l(2)35Aa) (Protein-UDP acetylgalactosaminyltransferase 35A) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 35A) (pp-GaNTase 35A) (dGalNAc-T1),GO:0000139; GO:0005795; GO:0016021; GO:0009312; GO:0007424; GO:0004653; GO:0006486,Golgi membrane; Golgi stack; integral to membrane; oligosaccharide biosynthetic process; open tracheal system development; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,,,,,,,,,GLT35_DROME,Drosophila melanogaster (Fruit fly),oligosaccharide biosynthetic process [GO:0009312]; open tracheal system development [GO:0007424]; protein glycosylation [GO:0006486] comp27872_c0_seq1,216,68.9815,1.14006067,0,12,,2.00E-17,Q42450,"Ribulose bisphosphate carboxylase/oxygenase activase B, chloroplastic (RA B) (RuBisCO activase B)","Ribulose bisphosphate carboxylase/oxygenase activase B, chloroplastic (RA B) (RuBisCO activase B)",GO:0005524; GO:0009570,ATP binding; chloroplast stroma,PF00004;,,,,,,,,,RCAB_HORVU,Hordeum vulgare (Barley), comp27876_c0_seq1,274,56.2044,1.06969123,0,29,,5.00E-06,Q9CDE9,Probable peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Rotamase A),Probable peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Rotamase A),GO:0005737; GO:0003755; GO:0006457; GO:0000413,cytoplasm; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,,,,,,,,,PPIA_MYCLE,Mycobacterium leprae (strain TN),protein folding [GO:0006457] comp27880_c0_seq1,221,69.6833,1.14258644,0,14,,5.00E-13,O78518,Acetolactate synthase large subunit (AHAS) (EC 2.2.1.6) (Acetohydroxy-acid synthase large subunit) (ALS),Acetolactate synthase large subunit (AHAS) (EC 2.2.1.6) (Acetohydroxy-acid synthase large subunit) (ALS),GO:0003984; GO:0009507; GO:0050660; GO:0009097; GO:0000287; GO:0030976; GO:0009099,acetolactate synthase activity; chloroplast; flavin adenine dinucleotide binding; isoleucine biosynthetic process; magnesium ion binding; thiamine pyrophosphate binding; valine biosynthetic process,PF02775;PF00205;PF02776;,,,,,,,,,ILVB_GUITH,Guillardia theta (Cryptomonas phi),isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] comp27892_c0_seq1,204,39.7059,0.39678373,1,10,,4.00E-20,Q63356,Unconventional myosin-Ie (Myosin heavy chain myr 3) (Unconventional myosin 1E),Unconventional myosin-Ie (Myosin heavy chain myr 3) (Unconventional myosin 1E),GO:0005524; GO:0042623; GO:0051015; GO:0005912; GO:0005516; GO:0005911; GO:0030136; GO:0005737; GO:0005856; GO:0006897; GO:0032836; GO:0003094; GO:0072015; GO:0003774; GO:0016459; GO:0035091; GO:0043234,"ATP binding; ATPase activity, coupled; actin filament binding; adherens junction; calmodulin binding; cell-cell junction; clathrin-coated vesicle; cytoplasm; cytoskeleton; endocytosis; glomerular basement membrane development; glomerular filtration; glomerular visceral epithelial cell development; motor activity; myosin complex; phosphatidylinositol binding; protein complex",PF00063;PF06017;PF00018;,,,,,,,,,MYO1E_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015] comp27914_c0_seq1,635,41.2598,0.71351145,28,127,,7.00E-126,Q5R8Z8,Ras-related protein Rab-14,Ras-related protein Rab-14,GO:0019003; GO:0005525; GO:0003924; GO:0000139; GO:0006895; GO:0031901; GO:0009790; GO:0032456; GO:0008543; GO:0045335; GO:0030670; GO:0015031; GO:0055037; GO:0032880; GO:0007264,GDP binding; GTP binding; GTPase activity; Golgi membrane; Golgi to endosome transport; early endosome membrane; embryo development; endocytic recycling; fibroblast growth factor receptor signaling pathway; phagocytic vesicle; phagocytic vesicle membrane; protein transport; recycling endosome; regulation of protein localization; small GTPase mediated signal transduction,PF00071;,2.00E-142,CHOYP_LOC762871.1.1,,,,,,,RAB14_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),defense response to bacterium [GO:0042742]; embryo development [GO:0009790]; endocytic recycling [GO:0032456]; fibroblast growth factor receptor signaling pathway [GO:0008543]; Golgi to endosome transport [GO:0006895]; phagosome maturation [GO:0090382]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]; small GTPase mediated signal transduction [GO:0007264] comp27970_c0_seq1,650,38.7692,0.84353941,18,148,,9.00E-12,Q9SAR5,Ankyrin repeat domain-containing protein 2 (AtAKR2),Ankyrin repeat domain-containing protein 2A (AtAKR2),,,,5.00E-18,CHOYP_LOC100368623.1.1,4.00E-61,ruditapes_c14382,,,,,AKR2_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp28020_c0_seq1,415,40.241,0.55368556,20,78,,2.00E-28,Q5R5J3,PRKR-interacting protein 1,PRKR-interacting protein 1,GO:0003725; GO:0005730; GO:0004860,double-stranded RNA binding; nucleolus; protein kinase inhibitor activity,PF06658;,2.00E-38,CHOYP_LOC100068258.1.1,,,,,,,PKRI1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of phosphorylation [GO:0042326]; negative regulation of protein kinase activity [GO:0006469]; renal system process [GO:0003014] comp28068_c0_seq1,220,43.1818,0.1976785,6,47,,3.00E-22,Q9UBZ4,DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2),DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2),GO:0003677; GO:0006310; GO:0006281; GO:0003906; GO:0007049; GO:0004519; GO:0004527; GO:0005743; GO:0090305; GO:0005634; GO:0008270,DNA binding; DNA recombination; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; cell cycle; endonuclease activity; exonuclease activity; mitochondrial inner membrane; nucleic acid phosphodiester bond hydrolysis; nucleus; zinc ion binding,PF03372;PF06839;,,,,,,,,,APEX2_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310] comp2813_c0_seq1,221,46.1538,0.60586036,7,0,,6.00E-18,Q9ERB4,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments),GO:0031103; GO:0005509; GO:0030246; GO:0007155; GO:0006928; GO:0031012; GO:0005540; GO:0030169; GO:0005578,axon regeneration; calcium ion binding; carbohydrate binding; cell adhesion; cellular component movement; extracellular matrix; hyaluronic acid binding; low-density lipoprotein particle binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_RAT,Rattus norvegicus (Rat),axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; response to wounding [GO:0009611]; skeletal system development [GO:0001501] comp28151_c0_seq1,471,39.0658,0.87798015,2,81,,3.00E-12,Q6DCC7,LysM and putative peptidoglycan-binding domain-containing protein 4,LysM and putative peptidoglycan-binding domain-containing protein 4,GO:0016998; GO:0016021,cell wall macromolecule catabolic process; integral to membrane,,,,,,,,,,LYSM4_XENLA,Xenopus laevis (African clawed frog), comp28163_c0_seq1,235,35.3191,0.70239367,3,25,,1.00E-07,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,,,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp28188_c0_seq1,280,44.2857,0.46990566,4,59,,6.00E-33,Q0VD26,MORN repeat-containing protein 4,MORN repeat-containing protein 4,,,PF02493;,6.00E-31,CHOYP_MBLK1.1.1,,,,,,,MORN4_BOVIN,Bos taurus (Bovine), comp28203_c0_seq2,1572,35.5598,0.56601663,7,0,,8.00E-16,Q8VDN4,Coiled-coil domain-containing protein 92,Coiled-coil domain-containing protein 92,GO:0005814,centriole,,8.00E-20,CHOYP_LOC100767201.1.1,,,,,,,CCD92_MOUSE,Mus musculus (Mouse), comp28226_c0_seq1,307,57.329,0.73188895,43,215,,,,,,,,,8.00E-132,CHOYP_RN7SL2.1.1,,,,,,,,, comp28248_c0_seq1,577,39.688,0.71857248,881,1590,,2.00E-42,Q7ZUH5,"39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14)","39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF00238;,,,1.00E-48,ruditapes_c11279,,,,,RM14_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),translation [GO:0006412] comp28249_c0_seq1,1383,37.961,0.59098302,763,4531,,1.00E-109,Q28H87,Pre-mRNA-splicing factor 38A,Pre-mRNA-splicing factor 38A,GO:0008380; GO:0006397; GO:0005681,RNA splicing; mRNA processing; spliceosomal complex,PF03371;,3.00E-113,CHOYP_PR38A.1.1,,,,,,,PR38A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp28254_c0_seq1,1057,35.667,1.11909763,289,4063,,2.00E-14,P0CW97,Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3),GO:0016021,integral to membrane,PF04749;,,,3.00E-58,ruditapes2_c3305,,,,,PCR3_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp28257_c0_seq1,711,31.5049,0.29132627,417,2226,,6.00E-14,Q9W2D6,Mitochondrial import inner membrane translocase subunit Tim10,Mitochondrial import inner membrane translocase subunit Tim10,GO:0050829; GO:0046872; GO:0005743; GO:0042719; GO:0045824; GO:0045039; GO:0008565,defense response to Gram-negative bacterium; metal ion binding; mitochondrial inner membrane; mitochondrial intermembrane space protein transporter complex; negative regulation of innate immune response; protein import into mitochondrial inner membrane; protein transporter activity,PF02953;,,,,,,,,,TIM10_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; negative regulation of innate immune response [GO:0045824]; protein import into mitochondrial inner membrane [GO:0045039]; protein transport [GO:0015031] comp28264_c0_seq1,496,44.5565,0.6133808,39345,95679,,6.00E-70,Q7ZUB2,40S ribosomal protein S17,40S ribosomal protein S17,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00833;,2.00E-79,CHOYP_RS17.10.11,6.00E-115,ruditapes_lrc33333,,,,,RS17_COTJA,Coturnix coturnix japonica (Japanese quail) (Coturnix japonica),translation [GO:0006412] comp28265_c0_seq1,361,42.1053,0.5644534,62695,78660,,8.00E-26,Q90YP3,40S ribosomal protein S28,40S ribosomal protein S28,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01200;,1.00E-53,CHOYP_LOC764436.7.9,6.00E-37,ruditapes2_c40,,,,,RS28_ICTPU,Ictalurus punctatus (Channel catfish) (Silurus punctatus),translation [GO:0006412] comp28266_c0_seq1,632,40.981,0.65656052,93279,131807,,1.00E-71,P61354,60S ribosomal protein L27,60S ribosomal protein L27,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00467;PF01777;,1.00E-101,CHOYP_LOC100373506.2.8,9.00E-120,ruditapes_lrc32536,,,,,RL27_RAT,Rattus norvegicus (Rat),response to aldosterone [GO:1904044]; translation [GO:0006412] comp28267_c0_seq1,503,47.1173,0.78963423,56610,174423,,4.00E-45,P27085,40S ribosomal protein S26,40S ribosomal protein S26,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01283;,5.00E-67,CHOYP_RS26.7.15,2.00E-89,ruditapes2_c278,,,,,RS26_OCTVU,Octopus vulgaris (Common octopus),translation [GO:0006412] comp28268_c0_seq1,735,42.3129,0.45695449,55524,158593,,9.00E-81,P30050,60S ribosomal protein L12,60S ribosomal protein L12,GO:0003723; GO:0006614; GO:0022625; GO:0000184; GO:0003735; GO:0006414; GO:0006413; GO:0006415; GO:0019083,"RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosolic large ribosomal subunit; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; structural constituent of ribosome; translational elongation; translational initiation; translational termination; viral transcription",PF00298;PF03946;,7.00E-80,CHOYP_LOC100908688.3.5,2.00E-134,ruditapes_lrc7141,,,,,RL12_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]" comp28269_c0_seq1,580,40.1724,0.68524456,31836,107245,,4.00E-64,P61255,60S ribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20),60S ribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20),GO:0022625; GO:0006364; GO:0042273; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; rRNA processing; ribosomal large subunit biogenesis; structural constituent of ribosome; translation,PF00467;PF16906;,1.00E-76,CHOYP_LOC585872.5.6,1.00E-130,ruditapes_lrc32788,,,,,RL26_MOUSE,Mus musculus (Mouse),cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] comp28270_c0_seq1,1146,43.3682,0.46477927,61391,275155,,1.00E-144,Q9DG68,60S acidic ribosomal protein P0 (60S ribosomal protein L10E),60S acidic ribosomal protein P0 (60S ribosomal protein L10E),GO:0005840; GO:0042254; GO:0003735; GO:0006414,ribosome; ribosome biogenesis; structural constituent of ribosome; translational elongation,PF00466;,4.00E-142,CHOYP_RLA0.5.7,0,ruditapes2_c1283,,,,,RLA0_RANSY,Rana sylvatica (Wood frog),ribosome biogenesis [GO:0042254] comp28271_c0_seq1,1085,42.6728,0.43257121,78421,182502,,1.00E-153,Q0Z8U2,40S ribosomal protein S3,40S ribosomal protein S3 (EC 4.2.99.18),GO:0003723; GO:0030529; GO:0015935; GO:0003735; GO:0006412,RNA binding; ribonucleoprotein complex; small ribosomal subunit; structural constituent of ribosome; translation,PF07650;,0,CHOYP_RS3.7.7,0,ruditapes_lrc13423,,,,,RS3_PIG,Sus scrofa (Pig),"apoptotic process [GO:0006915]; cell division [GO:0051301]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]" comp28272_c0_seq1,615,40.4878,0.71544905,48269,103697,,2.00E-78,P46778,60S ribosomal protein L21,60S ribosomal protein L21,GO:0003723; GO:0006614; GO:0022625; GO:0000184; GO:0003735; GO:0006414; GO:0006413; GO:0006415; GO:0019083,"RNA binding; SRP-dependent cotranslational protein targeting to membrane; cytosolic large ribosomal subunit; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; structural constituent of ribosome; translational elongation; translational initiation; translational termination; viral transcription",PF01157;,2.00E-60,CHOYP_RL21.2.4,2.00E-116,ruditapes2_lrc4805,,,,,RL21_HUMAN,Homo sapiens (Human),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]" comp28273_c0_seq1,860,34.5349,0.70343232,3214,16709,,2.00E-54,P61805,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (EC 2.4.99.18) (Defender against cell death 1) (DAD-1),Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (EC 2.4.99.18) (Defender against cell death 1) (DAD-1),GO:0006915; GO:0001824; GO:0004579; GO:0016021; GO:0043066; GO:0008250; GO:0006486; GO:0042493; GO:0007584,apoptotic process; blastocyst development; dolichyl-diphosphooligosaccharide-protein glycotransferase activity; integral to membrane; negative regulation of apoptotic process; oligosaccharyltransferase complex; protein glycosylation; response to drug; response to nutrient,PF02109;,3.00E-47,CHOYP_LOC578220.2.2,6.00E-67,ruditapes_c613,,,,,DAD1_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of apoptotic process [GO:0043066]; protein glycosylation [GO:0006486]; response to drug [GO:0042493]; response to nutrient [GO:0007584] comp28275_c0_seq1,2407,34.275,0.31167125,6660,557,,3.00E-81,Q8AVY1,Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3),Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3),GO:0005737,cytoplasm,PF07004;,4.00E-70,CHOYP_BRAFLDRAFT_275083.1.2,,,,,,,ODF3A_XENLA,Xenopus laevis (African clawed frog), comp28276_c0_seq1,1258,46.1049,1.03391206,3616,485,,1.00E-89,P84239,Histone H3,Histone H3,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;,1.00E-142,CHOYP_LOC100902368.1.1,8.00E-99,ruditapes2_c1713,,,,,H3_URECA,Urechis caupo (Innkeeper worm) (Spoonworm), comp28277_c0_seq1,241,54.7718,0.89074457,984,2767,,8.00E-49,Q32KN8,Tubulin alpha-3 chain (Alpha-tubulin 3),Tubulin alpha-3 chain (Alpha-tubulin 3),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,4.00E-71,CHOYP_LOC584364.2.2,2.00E-73,ruditapes_c25365,,,,,TBA3_BOVIN,Bos taurus (Bovine),microtubule-based process [GO:0007017] comp28278_c0_seq1,600,37.8333,0.89266977,841,2127,,8.00E-23,Q9DGJ3,Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog),Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog),GO:0008203; GO:0005783; GO:0005576,cholesterol metabolic process; endoplasmic reticulum; extracellular region,PF02221;,,,7.00E-39,ruditapes_c11462,,,,,NPC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cholesterol metabolic process [GO:0008203] comp28280_c0_seq1,1766,39.4111,0.41401138,2004,7969,,0,P62335,26S protease regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Conserved ATPase domain protein 44) (CADp44) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42),26S protease regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Conserved ATPase domain protein 44) (CADp44) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42),GO:0005524; GO:0005737; GO:0017111; GO:0005634; GO:0005886; GO:0022624; GO:0030163,ATP binding; cytoplasm; nucleoside-triphosphatase activity; nucleus; plasma membrane; proteasome accessory complex; protein catabolic process,PF00004;,0,CHOYP_PSMC6.1.1,0,ruditapes2_c461,2.00E-135,AM868500.p.cg.6,8,,PRS10_SPETR,Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus),protein catabolic process [GO:0030163] comp28281_c0_seq1,2368,41.0895,0.51349088,6251,17554,,8.00E-176,Q9NR30,Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu),Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu),GO:0005524; GO:0004004; GO:0003725; GO:0005730; GO:0043330; GO:0009615,ATP binding; ATP-dependent RNA helicase activity; double-stranded RNA binding; nucleolus; response to exogenous dsRNA; response to virus,PF00270;PF08152;PF00271;,,,,,,,,,DDX21_HUMAN,Homo sapiens (Human),"osteoblast differentiation [GO:0001649]; positive regulation of gene expression, epigenetic [GO:0045815]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]; transcription from RNA polymerase II promoter [GO:0006366]" comp28282_c0_seq1,1635,35.9021,0.93392085,3789,1103,,6.00E-55,P83863,Histone H2B (Fragments),Histone H2B (Fragments),GO:0003677; GO:0042742; GO:0005811; GO:0000786; GO:0006334; GO:0005634,DNA binding; defense response to bacterium; lipid particle; nucleosome; nucleosome assembly; nucleus,PF00125;,2.00E-96,CHOYP_H2B.1.2,,,,,,,H2B_LITVA,Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei),defense response to bacterium [GO:0042742] comp28285_c0_seq1,919,45.8107,0.83088832,1463,8493,,6.00E-38,P35003,Chymotrypsin-like serine proteinase (EC 3.4.21.-),Chymotrypsin-like serine proteinase (EC 3.4.21.-),GO:0005615; GO:0006508; GO:0004252,extracellular space; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,CTRL_HALRU,Haliotis rufescens (California red abalone), comp28288_c0_seq1,870,43.2184,0.62544963,711,9154,,3.00E-39,Q49117,Uncharacterized oxidoreductase MexAM1_META1p0182 (EC 1.-.-.-) (ORFC),Uncharacterized oxidoreductase MexAM1_META1p0182 (EC 1.-.-.-) (ORFC),GO:0016491,oxidoreductase activity,,3.00E-86,CHOYP_LOC101161976.1.1,4.00E-120,ruditapes2_c116,,,,,Y182_METEA,Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1), comp28296_c0_seq1,914,33.0416,0.7339581,240,1590,,1.00E-44,A5PLH4,TM2 domain-containing protein 1,TM2 domain-containing protein 1,GO:0016021,integral to membrane,PF05154;,2.00E-36,CHOYP_ISCW_ISCW020476.1.1,,,,,,,TM2D1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp28298_c0_seq1,1186,37.0152,0.51769507,525,2219,,5.00E-80,Q8WUJ0,Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein),Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein),GO:0005737; GO:0004721; GO:0007283,cytoplasm; phosphoprotein phosphatase activity; spermatogenesis,PF00782;,2.00E-27,CHOYP_NEMVEDRAFT_V1G246990.1.1,,,,,,,STYX_HUMAN,Homo sapiens (Human),MAPK export from nucleus [GO:0045204]; regulation of ERK1 and ERK2 cascade [GO:0070372]; spermatogenesis [GO:0007283] comp28299_c0_seq1,603,45.937,0.88674741,509,778,,4.00E-11,Q15582,Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP),Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP),GO:0001525; GO:0007155; GO:0008283; GO:0050840; GO:0030198; GO:0005615; GO:0070062; GO:0005178; GO:0007162; GO:0005886; GO:0005578; GO:0050896; GO:0007601,angiogenesis; cell adhesion; cell proliferation; extracellular matrix binding; extracellular matrix organization; extracellular space; extracellular vesicular exosome; integrin binding; negative regulation of cell adhesion; plasma membrane; proteinaceous extracellular matrix; response to stimulus; visual perception,PF02469;,,,5.00E-15,ruditapes2_c1646,,,,,BGH3_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cellular protein metabolic process [GO:0044267]; chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]; negative regulation of cell adhesion [GO:0007162]; response to stimulus [GO:0050896]; visual perception [GO:0007601] comp28301_c0_seq1,688,46.0756,0.93360631,2491,1449,,1.00E-49,Q6WV74,Histone H4,Histone H4,GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,,7.00E-99,CHOYP_LOC100903522.2.3,,,,,,,H4_MYTCH,Mytilus chilensis (Chilean blue mussel),"DNA-templated transcription, initiation [GO:0006352]; nucleosome assembly [GO:0006334]" comp28304_c0_seq1,873,35.2806,0.51700748,227,1471,,7.00E-52,Q6P1X6,UPF0598 protein C8orf82,UPF0598 protein C8orf82,GO:0005739,mitochondrion,PF14956;,1.00E-52,CHOYP_LOC579016.1.1,,,,,,,CH082_HUMAN,Homo sapiens (Human), comp28306_c0_seq1,1391,38.9648,0.39803942,17629,1292,,5.00E-86,Q4V7T8,Ropporin-1-like protein,Ropporin-1-like protein,,,PF02197;,5.00E-91,CHOYP_LOC589108.2.2,6.00E-164,ruditapes2_c2763,3.00E-91,AM861826.p.cg.6,5,,ROP1L_XENLA,Xenopus laevis (African clawed frog), comp28321_c0_seq1,1523,40.0525,0.37648238,67,94,,3.00E-18,Q8RY89,Phosphatidylinositol 4-phosphate 5-kinase 8 (AtPIP5K8) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 8) (Diphosphoinositide kinase 8) (PtdIns(4)P-5-kinase 8),Phosphatidylinositol 4-phosphate 5-kinase 8 (AtPIP5K8) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 8) (Diphosphoinositide kinase 8) (PtdIns(4)P-5-kinase 8),GO:0016308; GO:0005524; GO:0046854,1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; phosphatidylinositol phosphorylation,PF02493;PF01504;,3.00E-133,CHOYP_QCR2.1.1,,,,,,,PI5K8_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp28321_c0_seq2,1553,39.9227,0.37057768,716,28,,3.00E-79,Q8VIG3,Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein),Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein),GO:0005694; GO:0005829; GO:0007126; GO:0005634,chromosome; cytosol; meiosis; nucleus,PF02493;,2.00E-134,CHOYP_LOC100375551.2.2,,,,,,,RSPH1_MOUSE,Mus musculus (Mouse),axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] comp28323_c0_seq1,1163,32.5881,0.6483962,1815,6075,,3.00E-30,Q3B8G7,Immediate early response 3-interacting protein 1,Immediate early response 3-interacting protein 1,GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF08571;,,,,,,,,,IR3IP_XENLA,Xenopus laevis (African clawed frog), comp28344_c0_seq1,974,41.0678,1.07637608,9514,66,male>female,2.00E-23,Q9DAN9,Uncharacterized protein C17orf105 homolog,Uncharacterized protein C17orf105 homolog,,,PF13879;,2.00E-25,CHOYP_NEMVEDRAFT_V1G240545.1.3,,,,,,,CQ105_MOUSE,Mus musculus (Mouse), comp2835_c0_seq1,227,42.2907,0.91608921,5,0,,2.00E-07,P45380,Sulfate anion transporter 1 (SAT-1) (Canalicular sulfate transporter) (Solute carrier family 26 member 1) (Sulfate/carbonate antiporter),Sulfate anion transporter 1 (SAT-1) (Canalicular sulfate transporter) (Solute carrier family 26 member 1) (Sulfate/carbonate antiporter),GO:0015301; GO:0015108; GO:0016021; GO:0019531; GO:0008271; GO:0015116; GO:0008272,anion:anion antiporter activity; chloride transmembrane transporter activity; integral to membrane; oxalate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A1_RAT,Rattus norvegicus (Rat),bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sulfate transport [GO:0008272] comp2838_c0_seq1,315,46.3492,0.54608845,6,0,,3.00E-29,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp28391_c0_seq1,1403,29.5795,0.39554887,11018,504,,7.00E-25,A7SMR0,Meiosis expressed gene 1 protein homolog,Meiosis expressed gene 1 protein homolog,GO:0005634,nucleus,PF15163;,1.00E-11,CHOYP_UBC.2.3,,,,,,,MEIG1_NEMVE,Nematostella vectensis (Starlet sea anemone), comp28457_c0_seq1,521,47.2169,1.01190212,0,68,,2.00E-20,Q9BI23,Protein yellow,Protein yellow,GO:0005576; GO:0007275,extracellular region; multicellular organismal development,PF03022;,,,,,,,,,YELL_DROER,Drosophila erecta (Fruit fly),male mating behavior [GO:0060179]; melanin biosynthetic process [GO:0042438]; multicellular organism development [GO:0007275] comp28465_c0_seq1,224,42.4107,0.87978293,0,34,,9.00E-11,Q9ULI3,Protein HEG homolog 1,Protein HEG homolog 1,GO:0005509; GO:0003209; GO:0005911; GO:0045216; GO:0001886; GO:0009897; GO:0005576; GO:0001701; GO:0016021; GO:0030324; GO:0003017; GO:0001945; GO:0035264; GO:0060039; GO:0009791; GO:0050878; GO:0001570; GO:0048845; GO:0003281,calcium ion binding; cardiac atrium morphogenesis; cell-cell junction; cell-cell junction organization; endothelial cell morphogenesis; external side of plasma membrane; extracellular region; in utero embryonic development; integral to membrane; lung development; lymph circulation; lymph vessel development; multicellular organism growth; pericardium development; post-embryonic development; regulation of body fluid levels; vasculogenesis; venous blood vessel morphogenesis; ventricular septum development,PF00008;PF07645;,,,,,,,,,HEG1_HUMAN,Homo sapiens (Human),cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp28468_c0_seq1,281,46.2633,0.9364445,2,27,,9.00E-12,Q640D5,Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B),Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B),GO:0031519; GO:0016568; GO:0006355; GO:0006351; GO:0008270,"PcG protein complex; chromatin modification; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF16207;,,,,,,,,,BMI1B_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; negative regulation of gene expression, epigenetic [GO:0045814]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp28508_c0_seq1,417,45.0839,0.26753866,7,31,,1.00E-14,Q9VUX2,E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib),E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib),GO:0007219; GO:0045179; GO:0005829; GO:0006897; GO:0046331; GO:0045747; GO:0008104; GO:0007423; GO:0004842; GO:0008270,Notch signaling pathway; apical cortex; cytosol; endocytosis; lateral inhibition; positive regulation of Notch signaling pathway; protein localization; sensory organ development; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB_DROME,Drosophila melanogaster (Fruit fly),compound eye development [GO:0048749]; endocytosis [GO:0006897]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of Notch signaling pathway [GO:0008593]; sensory organ development [GO:0007423] comp28515_c0_seq1,336,43.1548,1.02980286,1,49,,2.00E-18,Q95R48,Organic cation transporter-like protein,Organic cation transporter-like protein,GO:0007390; GO:0016021; GO:0015101; GO:0030307; GO:0040018,germ-band shortening; integral to membrane; organic cation transmembrane transporter activity; positive regulation of cell growth; positive regulation of multicellular organism growth,PF00083;,,,,,,,,,OCTL_DROME,Drosophila melanogaster (Fruit fly),germ-band shortening [GO:0007390]; organic cation transport [GO:0015695]; positive regulation of cell growth [GO:0030307]; positive regulation of multicellular organism growth [GO:0040018] comp28518_c0_seq1,322,45.3416,0.48819666,5,51,,5.00E-08,Q80U72,Protein scribble homolog (Scribble) (Protein LAP4),Protein scribble homolog (Scribble) (Protein LAP4),GO:0032863; GO:0060561; GO:0008105; GO:0016323; GO:0016477; GO:0008283; GO:0005913; GO:0016337; GO:0005737; GO:0035089; GO:0060603; GO:0035748; GO:0045930; GO:0001843; GO:0050918; GO:0043065; GO:0048488; GO:0016080; GO:0042060,activation of Rac GTPase activity; apoptotic process involved in morphogenesis; asymmetric protein localization; basolateral plasma membrane; cell migration; cell proliferation; cell-cell adherens junction; cell-cell adhesion; cytoplasm; establishment of apical/basal cell polarity; mammary gland duct morphogenesis; myelin sheath abaxonal region; negative regulation of mitotic cell cycle; neural tube closure; positive chemotaxis; positive regulation of apoptotic process; synaptic vesicle endocytosis; synaptic vesicle targeting; wound healing,PF13855;PF00595;,,,,,,,,,SCRIB_MOUSE,Mus musculus (Mouse),"activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; asymmetric protein localization [GO:0008105]; auditory receptor cell morphogenesis [GO:0002093]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; mammary gland duct morphogenesis [GO:0060603]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; protein localization to adherens junction [GO:0071896]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp28527_c0_seq1,558,48.9247,0.45017862,2,7,,2.00E-06,Q91Y25,WASH complex subunit FAM21,WASH complex subunit FAM21,GO:0071203; GO:0005769; GO:0031901; GO:0042147,"WASH complex; early endosome; early endosome membrane; retrograde transport, endosome to Golgi",PF15255;,,,,,,,,,FAM21_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),"protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp28536_c0_seq1,409,42.0538,1.09610899,13,35,,1.00E-29,Q5XIY2,Transmembrane protein 56-B,Transmembrane protein 56-B,GO:0016021,integral to membrane,PF03798;,,,,,,,,,TM56B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp28549_c0_seq1,1038,41.2331,0.91086503,47,60,,6.00E-19,Q8N8M0,Putative N-acetyltransferase 16 (EC 2.3.1.-),Probable N-acetyltransferase 16 (EC 2.3.1.-),GO:0008080,N-acetyltransferase activity,,,,,,,,,,NAT16_HUMAN,Homo sapiens (Human),N-terminal protein amino acid acetylation [GO:0006474] comp28556_c0_seq1,670,48.806,0.47702718,36,41,,5.00E-44,Q9VYY9,Ecotropic viral integration site 5 ortholog,Ecotropic viral integration site 5 ortholog,GO:0005097; GO:0007298; GO:0005737; GO:0005768; GO:0030334; GO:0032880; GO:0031982,Rab GTPase activator activity; border follicle cell migration; cytoplasm; endosome; regulation of cell migration; regulation of protein localization; vesicle,PF00566;,3.00E-46,CHOYP_LOC100378224.1.1,,,,,,,Y1727_DROME,Drosophila melanogaster (Fruit fly),activation of GTPase activity [GO:0090630]; border follicle cell migration [GO:0007298]; intracellular protein transport [GO:0006886]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338] comp28584_c0_seq1,361,42.6593,0.430005,1,42,,1.00E-08,Q9QZD5,Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2),Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2),GO:0005096; GO:0004663; GO:0005968; GO:0006886; GO:0043547,GTPase activator activity; Rab geranylgeranyltransferase activity; Rab-protein geranylgeranyltransferase complex; intracellular protein transport; positive regulation of GTPase activity,PF00996;,,,,,,,,,RAE2_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; protein geranylgeranylation [GO:0018344]; small GTPase mediated signal transduction [GO:0007264] comp28596_c0_seq1,226,38.9381,0.12126306,5,0,,3.00E-14,O14975,"Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)","Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)",GO:0005524; GO:0006699; GO:0005788; GO:0001561; GO:0006635; GO:0015245; GO:0030176; GO:0005779; GO:0044539; GO:0004467; GO:0097089; GO:0005739; GO:0050197; GO:0070251; GO:0042760; GO:0031957,ATP binding; bile acid biosynthetic process; endoplasmic reticulum lumen; fatty acid alpha-oxidation; fatty acid beta-oxidation; fatty acid transporter activity; integral to endoplasmic reticulum membrane; integral to peroxisomal membrane; long-chain fatty acid import; long-chain fatty acid-CoA ligase activity; methyl-branched fatty acid metabolic process; mitochondrion; phytanate-CoA ligase activity; pristanate-CoA ligase activity; very long-chain fatty acid catabolic process; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,S27A2_HUMAN,Homo sapiens (Human),bile acid biosynthetic process [GO:0006699]; fatty acid alpha-oxidation [GO:0001561]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; methyl-branched fatty acid metabolic process [GO:0097089]; very long-chain fatty acid catabolic process [GO:0042760] comp28644_c0_seq1,270,47.037,0.83385759,1,22,,2.00E-16,Q12553,Xanthine dehydrogenase (EC 1.17.1.4) (Purine hydroxylase I),Xanthine dehydrogenase (EC 1.17.1.4) (Purine hydroxylase I),GO:0051537; GO:0008762; GO:0009055; GO:0050660; GO:0005506; GO:0043546; GO:0005777; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdopterin cofactor binding; peroxisome; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),purine nucleobase catabolic process [GO:0006145]; xanthine catabolic process [GO:0009115] comp28669_c0_seq1,316,58.8608,1.03210336,0,27,,4.00E-57,Q9M5Z9,40S ribosomal protein S23,40S ribosomal protein S23,GO:0015935; GO:0003735; GO:0006412,small ribosomal subunit; structural constituent of ribosome; translation,PF00164;,4.00E-47,CHOYP_RS23.7.9,1.00E-39,ruditapes2_c142,,,,,RS23_EUPES,Euphorbia esula (Leafy spurge),translation [GO:0006412] comp28681_c0_seq1,605,47.9339,0.76392936,14,71,,3.00E-55,Q9CZR2,N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II),N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II),GO:0050129; GO:0004180; GO:0016805; GO:0016021; GO:0046872; GO:0008237; GO:0042135; GO:0006508,N-formylglutamate deformylase activity; carboxypeptidase activity; dipeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; neurotransmitter catabolic process; proteolysis,PF02225;PF04389;PF04253;,7.00E-22,CHOYP_LOC579656.3.5,,,,,,,NALD2_MOUSE,Mus musculus (Mouse),neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] comp28684_c0_seq1,265,66.0377,1.07736052,0,44,,5.00E-29,Q9XHS0,40S ribosomal protein S12,40S ribosomal protein S12,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01248;,,,,,,,,,RS12_HORVU,Hordeum vulgare (Barley),translation [GO:0006412] comp28688_c0_seq1,318,38.9937,0.59979105,0,48,,3.00E-20,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp28734_c0_seq1,966,39.9586,1.01256653,6,114,,2.00E-13,Q9VQB7,EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),GO:0005788; GO:0008363; GO:0016262; GO:0097363; GO:0097370,endoplasmic reticulum lumen; larval chitin-based cuticle development; protein N-acetylglucosaminyltransferase activity; protein O-GlcNAc transferase activity; protein O-GlcNAcylation via threonine,PF04577;,,,,,,,,,EOGT_DROME,Drosophila melanogaster (Fruit fly),larval chitin-based cuticle development [GO:0008363]; metabolic process [GO:0008152]; protein O-GlcNAcylation via threonine [GO:0097370]; protein O-linked glycosylation [GO:0006493] comp28752_c0_seq1,342,41.2281,1.38196186,5,14,,8.00E-11,Q05707,Collagen alpha-1(XIV) chain (Undulin),Collagen alpha-1(XIV) chain (Undulin),GO:0016337; GO:0005518; GO:0030574; GO:0030199; GO:0005596; GO:0005788; GO:0022617; GO:0005201; GO:0005615; GO:0048873; GO:0005614; GO:0030674; GO:0061050; GO:0003229,"cell-cell adhesion; collagen binding; collagen catabolic process; collagen fibril organization; collagen type XIV; endoplasmic reticulum lumen; extracellular matrix disassembly; extracellular matrix structural constituent; extracellular space; homeostasis of number of cells within a tissue; interstitial matrix; protein binding, bridging; regulation of cell growth involved in cardiac muscle cell development; ventricular cardiac muscle tissue development",PF01391;PF00041;PF00092;,8.00E-12,CHOYP_COCA1.5.6,,,,,,,COEA1_HUMAN,Homo sapiens (Human),collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; single organismal cell-cell adhesion [GO:0016337] comp28754_c0_seq1,362,42.2652,0.78065112,0,50,,2.00E-32,Q5EA62,Fibulin-5 (FIBL-5),Fibulin-5 (FIBL-5),GO:0005509; GO:0007155; GO:0005576,calcium ion binding; cell adhesion; extracellular region,PF12662;PF07645;,,,,,,,,,FBLN5_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; elastic fiber assembly [GO:0048251] comp28768_c0_seq1,809,48.0841,0.471579,24,37,,2.00E-34,Q9HCK4,Roundabout homolog 2,Roundabout homolog 2,GO:0061364; GO:0030673; GO:0008046; GO:0016199; GO:0009986; GO:0032870; GO:0007156; GO:0042802; GO:0016021; GO:0001656; GO:0050925; GO:0051964; GO:0021891; GO:0050772; GO:0031290; GO:0001657,apoptotic process involved in luteolysis; axolemma; axon guidance receptor activity; axon midline choice point recognition; cell surface; cellular response to hormone stimulus; homophilic cell adhesion; identical protein binding; integral to membrane; metanephros development; negative regulation of negative chemotaxis; negative regulation of synapse assembly; olfactory bulb interneuron development; positive regulation of axonogenesis; retinal ganglion cell axon guidance; ureteric bud development,PF00041;PF07679;,,,,,,,,,ROBO2_HUMAN,Homo sapiens (Human),apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657] comp28769_c0_seq1,479,35.9081,0.69015398,14,64,,5.00E-20,Q7T2B9,Myotrophin,Myotrophin,GO:0005634; GO:0048471,nucleus; perinuclear region of cytoplasm,PF12796;,,,,,,,,,MTPN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp28799_c0_seq1,948,40.2954,0.67293585,16,112,,3.00E-52,Q58DL5,Breast cancer anti-estrogen resistance protein 3,Breast cancer anti-estrogen resistance protein 3,GO:0005085; GO:0005622; GO:0007264,guanyl-nucleotide exchange factor activity; intracellular; small GTPase mediated signal transduction,PF00617;PF00017;,,,,,,,,,BCAR3_BOVIN,Bos taurus (Bovine),small GTPase mediated signal transduction [GO:0007264] comp28824_c0_seq1,482,38.3817,0.22692134,10,50,,6.00E-20,Q5RED8,Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD),Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD),GO:0016055; GO:0005829; GO:0005874; GO:0042347; GO:0032088; GO:0090090; GO:0048471; GO:0005886; GO:0070536; GO:0004221; GO:0006511; GO:0004843; GO:0008270,Wnt receptor signaling pathway; cytosol; microtubule; negative regulation of NF-kappaB import into nucleus; negative regulation of NF-kappaB transcription factor activity; negative regulation of canonical Wnt receptor signaling pathway; perinuclear region of cytoplasm; plasma membrane; protein K63-linked deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding,PF01302;PF00443;,2.00E-28,CHOYP_BRAFLDRAFT_230143.1.1,,,,,,,CYLD_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein K63-linked deubiquitination [GO:0070536]; regulation of cilium assembly [GO:1902017]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] comp28833_c0_seq1,259,37.8378,0.66753242,5,22,,7.00E-10,Q76MJ5,Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0030263; GO:0007050; GO:0004519; GO:0005789; GO:0016021; GO:0006397; GO:0000287; GO:0045892; GO:0004674; GO:0016075; GO:0006950; GO:0004540; GO:0006351,"ATP binding; apoptotic chromosome condensation; cell cycle arrest; endonuclease activity; endoplasmic reticulum membrane; integral to membrane; mRNA processing; magnesium ion binding; negative regulation of transcription, DNA-dependent; protein serine/threonine kinase activity; rRNA catabolic process; response to stress; ribonuclease activity; transcription, DNA-dependent",PF00069;PF06479;,,,,,,,,,ERN2_HUMAN,Homo sapiens (Human),"apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]" comp28839_c0_seq1,989,43.6805,0.51111116,46,31,,1.00E-130,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,1.00E-59,CHOYP_BRAFLDRAFT_119774.1.4,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp28846_c0_seq1,571,55.5166,0.91554085,3,80,,2.00E-29,P11680,Properdin (Complement factor P),Properdin (Complement factor P),GO:0006957; GO:0031012; GO:0005576,"complement activation, alternative pathway; extracellular matrix; extracellular region",PF00090;,,,,,,,,,PROP_MOUSE,Mus musculus (Mouse),"complement activation, alternative pathway [GO:0006957]" comp28847_c0_seq1,378,44.1799,0.3411365,11,46,,7.00E-41,Q2KJA1,Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1),Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1),GO:0030054; GO:0042995; GO:0031901; GO:0006897; GO:0008289; GO:0002102,cell junction; cell projection; early endosome membrane; endocytosis; lipid binding; podosome,PF03114;PF00018;,3.00E-31,CHOYP_ISCW_ISCW008555.1.1,,,,,,,SH3G1_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897] comp28892_c0_seq1,203,33.4975,0.73714526,3,29,,1.00E-20,Q3KNS6,Zinc finger protein 829,Zinc finger protein 829,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,2.00E-11,CHOYP_PRDM9.1.1,,,,,,,ZN829_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp28900_c0_seq1,288,45.1389,0.48618707,13,29,,1.00E-48,Q8BX09,Retinoblastoma-binding protein 5 (RBBP-5),Retinoblastoma-binding protein 5 (RBBP-5),GO:0071339; GO:0048188; GO:0042800; GO:0006355; GO:0006974; GO:0043627; GO:0044212; GO:0006351,"MLL1 complex; Set1C/COMPASS complex; histone methyltransferase activity (H3-K4 specific); regulation of transcription, DNA-dependent; response to DNA damage stimulus; response to estrogen stimulus; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00400;,2.00E-56,CHOYP_BRAFLDRAFT_203393.2.2,,,,,,,RBBP5_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]" comp28905_c0_seq1,356,42.4157,1.12777303,20,23,,1.00E-16,Q9DBG1,"Sterol 26-hydroxylase, mitochondrial (EC 1.14.13.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)","Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)",GO:0036378; GO:0047749; GO:0031073; GO:0008203; GO:0020037; GO:0005506; GO:0005743; GO:0030343,calcitriol biosynthetic process from calciol; cholestanetriol 26-monooxygenase activity; cholesterol 26-hydroxylase activity; cholesterol metabolic process; heme binding; iron ion binding; mitochondrial inner membrane; vitamin D3 25-hydroxylase activity,PF00067;,,,,,,,,,CP27A_MOUSE,Mus musculus (Mouse), comp28915_c0_seq1,743,40.646,0.5553224,18,51,,4.00E-15,Q60674,Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),GO:0003677; GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0004887; GO:0008270,DNA binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR1D2_MOUSE,Mus musculus (Mouse),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp28920_c0_seq1,537,44.5065,0.68690833,3,43,,2.00E-06,P27352,Gastric intrinsic factor (Intrinsic factor) (IF) (INF),Gastric intrinsic factor (Intrinsic factor) (IF) (INF),GO:0016324; GO:0031419; GO:0009235; GO:0015889; GO:0006824; GO:0005768; GO:0005615; GO:0043202; GO:0005902,apical plasma membrane; cobalamin binding; cobalamin metabolic process; cobalamin transport; cobalt ion transport; endosome; extracellular space; lysosomal lumen; microvillus,PF01122;PF14478;,,,,,,,,,IF_HUMAN,Homo sapiens (Human),cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; cobalt ion transport [GO:0006824] comp28924_c0_seq1,506,45.4545,0.77257445,6,42,,6.00E-08,Q8IVG9,Putative humanin peptide,Humanin (Humanin mitochondrial) (HNM),GO:0006915; GO:0006879; GO:0005576; GO:0030595; GO:0005739; GO:0043066; GO:0048471; GO:0048019,apoptotic process; cellular iron ion homeostasis; extracellular region; leukocyte chemotaxis; mitochondrion; negative regulation of apoptotic process; perinuclear region of cytoplasm; receptor antagonist activity,PF15040;,0,CHOYP_MTRNR2L14.1.2,1.00E-15,ruditapes_c16723,,,,,HUNIN_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular iron ion homeostasis [GO:0006879]; leukocyte chemotaxis [GO:0030595]; negative regulation of apoptotic process [GO:0043066] comp28956_c0_seq1,432,42.3611,0.42161862,9,36,,1.00E-11,O49286,F-box protein SKP2B (F-box/LRR-repeat protein 5) (AtFB5) (SKP2-like protein 2) (AtSKP2;2),F-box protein SKP2B (F-box/LRR-repeat protein 5) (AtFB5) (SKP2-like protein 2) (AtSKP2;2),GO:0010286; GO:1901332; GO:0051603,heat acclimation; negative regulation of lateral root development; proteolysis involved in cellular protein catabolic process,PF00646;PF13516;,,,,,,,,,SKP2B_ARATH,Arabidopsis thaliana (Mouse-ear cress),heat acclimation [GO:0010286]; negative regulation of lateral root development [GO:1901332]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp28959_c0_seq1,527,41.9355,0.65249864,8,61,,3.00E-14,Q9ULL5,Proline-rich protein 12,Proline-rich protein 12,GO:0003677,DNA binding,PF13926;,,,,,,,,,PRR12_HUMAN,Homo sapiens (Human), comp28962_c0_seq1,383,40.9922,0.64516569,0,63,,4.00E-22,Q99M80,Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (RPTPmam4) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho) (mRPTPrho),Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (RPTPmam4) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho) (mRPTPrho),GO:0051393; GO:0045294; GO:0008013; GO:0009986; GO:0007156; GO:0016021; GO:0005886; GO:0004725; GO:0016790; GO:0007169,alpha-actinin binding; alpha-catenin binding; beta-catenin binding; cell surface; homophilic cell adhesion; integral to membrane; plasma membrane; protein tyrosine phosphatase activity; thiolester hydrolase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF00041;PF00629;PF00102;,,,,,,,,,PTPRT_MOUSE,Mus musculus (Mouse),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp2896_c0_seq1,242,47.1074,0.22465715,6,0,,4.00E-16,Q8NFP4,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,5.00E-25,CHOYP_LOC580670.1.6,,,,,,,MDGA1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp28983_c0_seq1,361,40.1662,0.36084806,20,12,,5.00E-14,Q9HCU4,Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3),GO:0004930; GO:0016055; GO:0005509; GO:0033326; GO:0042384; GO:0003341; GO:0005737; GO:0048813; GO:0007156; GO:0016021; GO:0021999; GO:0001764; GO:0007218; GO:0005886; GO:0022407; GO:0032880; GO:0006355; GO:0021591,"G-protein coupled receptor activity; Wnt receptor signaling pathway; calcium ion binding; cerebrospinal fluid secretion; cilium assembly; cilium movement; cytoplasm; dendrite morphogenesis; homophilic cell adhesion; integral to membrane; neural plate anterior/posterior regionalization; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of cell-cell adhesion; regulation of protein localization; regulation of transcription, DNA-dependent; ventricular system development",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR2_HUMAN,Homo sapiens (Human),"dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp28984_c0_seq1,254,40.9449,1.07720564,0,41,,4.00E-10,Q684R7,FRAS1-related extracellular matrix protein 1 (Protein QBRICK),FRAS1-related extracellular matrix protein 1 (Protein QBRICK),GO:0005604; GO:0030246; GO:0007154; GO:0007160; GO:0097094; GO:0016021; GO:0046872,basement membrane; carbohydrate binding; cell communication; cell-matrix adhesion; craniofacial suture morphogenesis; integral to membrane; metal ion binding,PF03160;PF00059;,,,,,,,,,FREM1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] comp29007_c0_seq1,212,29.2453,0,13,19,,2.00E-12,Q7TQN8,Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119),Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119),GO:0004930; GO:0030073; GO:0016021; GO:0031210; GO:0005886,G-protein coupled receptor activity; insulin secretion; integral to membrane; phosphatidylcholine binding; plasma membrane,PF00001;,,,,,,,,,GP119_RAT,Rattus norvegicus (Rat),insulin secretion [GO:0030073] comp29010_c0_seq1,904,42.8097,0.51453929,24,70,,5.00E-94,Q9NP78,ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL),ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL),GO:0005524; GO:0042288; GO:0042825; GO:0046978; GO:0046979; GO:0005765; GO:0015421; GO:0042605; GO:0005886; GO:0001916; GO:0042803; GO:0015031; GO:0046980,ATP binding; MHC class I protein binding; TAP complex; TAP1 binding; TAP2 binding; lysosomal membrane; oligopeptide-transporting ATPase activity; peptide antigen binding; plasma membrane; positive regulation of T cell mediated cytotoxicity; protein homodimerization activity; protein transport; tapasin binding,PF00664;PF00005;,,,,,,,,,ABCB9_HUMAN,Homo sapiens (Human),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]" comp29011_c0_seq1,638,41.0658,0.3431188,12,59,,3.00E-20,Q9QY66,Zinc finger HIT domain-containing protein 2 (Protein FON),Zinc finger HIT domain-containing protein 2 (Protein FON),GO:0046872,metal ion binding,PF04438;,,,,,,,,,ZNHI2_MOUSE,Mus musculus (Mouse), comp29016_c0_seq1,751,42.743,0.23780578,23,21,,2.00E-11,Q9ER24,Ataxin-10 (Neuronal beta-catenin-like protein) (Spinocerebellar ataxia type 10 protein homolog),Ataxin-10 (Neuronal beta-catenin-like protein) (Spinocerebellar ataxia type 10 protein homolog),GO:0005829; GO:0030425; GO:0042802; GO:0031175; GO:0043025; GO:0048471,cytosol; dendrite; identical protein binding; neuron projection development; neuronal cell body; perinuclear region of cytoplasm,PF09759;,,,,,,,,,ATX10_RAT,Rattus norvegicus (Rat),cilium assembly [GO:0042384]; neuron projection development [GO:0031175]; protein homotrimerization [GO:0070207] comp29036_c0_seq1,484,38.6364,1.00901956,7,43,,2.00E-21,O75460,Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0070055; GO:0006987; GO:0006915; GO:0007050; GO:0004521; GO:0030176; GO:0000287; GO:0005739; GO:0005637; GO:1900103; GO:0046777; GO:0004674; GO:0006355; GO:0006351,"ATP binding; HAC1-type intron splice site recognition and cleavage; activation of signaling protein activity involved in unfolded protein response; apoptotic process; cell cycle arrest; endoribonuclease activity; integral to endoplasmic reticulum membrane; magnesium ion binding; mitochondrion; nuclear inner membrane; positive regulation of endoplasmic reticulum unfolded protein response; protein autophosphorylation; protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;PF06479;,,,,,,,,,ERN1_HUMAN,Homo sapiens (Human),"activation of JUN kinase activity [GO:0007257]; activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cell cycle arrest [GO:0007050]; cellular response to glucose stimulus [GO:0071333]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial cell proliferation [GO:0001935]; insulin metabolic process [GO:1901142]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA catabolic process [GO:0006402]; mRNA cleavage [GO:0006379]; mRNA endonucleolytic cleavage involved in unfolded protein response [GO:0070055]; mRNA splicing, via endonucleolytic cleavage and ligation [GO:0070054]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine trans-autophosphorylation [GO:1990579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of macroautophagy [GO:0016241]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]" comp29037_c0_seq1,367,44.9591,0.86512544,0,0,,4.00E-08,Q01728,Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1),Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1),GO:0030315; GO:0030018; GO:1901660; GO:0070509; GO:0060402; GO:0005432; GO:0086064; GO:0071320; GO:0034614; GO:0043198; GO:0043197; GO:0005887; GO:0014704; GO:0046872; GO:0005874; GO:0005739; GO:0010763; GO:0010881; GO:0002028; GO:0033198; GO:0042493; GO:0009749; GO:0042542; GO:0001666; GO:0007584; GO:0071436; GO:0097369; GO:0021537,T-tubule; Z disc; calcium ion export; calcium ion import; calcium ion transport into cytosol; calcium:sodium antiporter activity; cell communication by electrical coupling involved in cardiac conduction; cellular response to cAMP; cellular response to reactive oxygen species; dendritic shaft; dendritic spine; integral to plasma membrane; intercalated disc; metal ion binding; microtubule; mitochondrion; positive regulation of fibroblast migration; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of sodium ion transport; response to ATP; response to drug; response to glucose stimulus; response to hydrogen peroxide; response to hypoxia; response to nutrient; sodium ion export; sodium ion import; telencephalon development,PF03160;PF01699;PF16494;,3.00E-11,CHOYP_LOC100371845.1.3,,,,,,,NAC1_RAT,Rattus norvegicus (Rat),calcium ion export [GO:1901660]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; cellular response to reactive oxygen species [GO:0034614]; cellular sodium ion homeostasis [GO:0006883]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of the force of heart contraction [GO:0098735]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of sodium ion transport [GO:0002028]; response to ATP [GO:0033198]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to muscle stretch [GO:0035994]; response to nutrient [GO:0007584]; sodium ion export [GO:0071436]; sodium ion import [GO:0097369]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537] comp29037_c0_seq2,490,45.3061,0.79727538,7,6,,,,,,,,,4.00E-11,CHOYP_LOC100371845.3.3,,,,,,,,, comp29042_c0_seq1,608,44.2434,0.88118076,19,58,,2.00E-78,O01346,"Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)","Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)",GO:0007411; GO:0019187; GO:0007298; GO:0045165; GO:0033227; GO:0006688; GO:0016021; GO:0042248; GO:0008049; GO:0045434; GO:0030720; GO:0016325; GO:0001744; GO:0007299; GO:0046662,"axon guidance; beta-1,4-mannosyltransferase activity; border follicle cell migration; cell fate commitment; dsRNA transport; glycosphingolipid biosynthetic process; integral to membrane; maintenance of polarity of follicular epithelium; male courtship behavior; negative regulation of female receptivity, post-mating; oocyte localization involved in germarium-derived egg chamber formation; oocyte microtubule cytoskeleton organization; optic lobe placode formation; ovarian follicle cell-cell adhesion; regulation of oviposition",PF13632;,,,,,,,,,EGH_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell fate commitment [GO:0045165]; dsRNA transport [GO:0033227]; germarium-derived egg chamber formation [GO:0007293]; germ cell development [GO:0007281]; glycosphingolipid biosynthetic process [GO:0006688]; maintenance of polarity of follicular epithelium [GO:0042248]; male courtship behavior [GO:0008049]; morphogenesis of follicular epithelium [GO:0016333]; negative regulation of female receptivity, post-mating [GO:0045434]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; optic lobe placode formation [GO:0001744]; ovarian follicle cell-cell adhesion [GO:0007299]; ovarian follicle cell development [GO:0030707]; peripheral nervous system neuron development [GO:0048935]; regulation of oviposition [GO:0046662]" comp29056_c0_seq1,257,43.9689,1.01178002,11,27,,2.00E-16,Q922Z0,D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),GO:0019478; GO:0003884; GO:0008445; GO:0006533; GO:0006531; GO:0048037; GO:0007625; GO:0042445; GO:0007320; GO:0005777,D-amino acid catabolic process; D-amino-acid oxidase activity; D-aspartate oxidase activity; aspartate catabolic process; aspartate metabolic process; cofactor binding; grooming behavior; hormone metabolic process; insemination; peroxisome,PF01266;,,,,,,,,,OXDD_MOUSE,Mus musculus (Mouse),aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; D-amino acid catabolic process [GO:0019478]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insemination [GO:0007320] comp29070_c0_seq1,517,45.2611,0.68518775,10,40,,1.00E-15,Q9GZV8,PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14),PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14),GO:0003677; GO:0001708; GO:0000902; GO:0009566; GO:0007281; GO:0048873; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell fate specification; cell morphogenesis; fertilization; germ cell development; homeostasis of number of cells within a tissue; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD14_HUMAN,Homo sapiens (Human),"cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of DNA methylation [GO:0044030]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]" comp29083_c0_seq1,248,32.2581,0.77862429,8,26,,7.00E-07,Q01514,Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (GBP-1) (mGBP-1) (mGBP1) (Guanine nucleotide-binding protein 1) (Interferon-gamma-inducible protein MAG-1),Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (mGBP-1) (mGBP1) (Guanine nucleotide-binding protein 1) (Interferon-gamma-inducible protein MAG-1) (Interferon-induced guanylate-binding protein 1),GO:0019002; GO:0005525; GO:0006184; GO:0003924; GO:0000139; GO:0051856; GO:0035458; GO:0071346; GO:0031410; GO:0050830; GO:0042832; GO:0051607; GO:0020005,GMP binding; GTP binding; GTP catabolic process; GTPase activity; Golgi membrane; adhesion to symbiont; cellular response to interferon-beta; cellular response to interferon-gamma; cytoplasmic vesicle; defense response to Gram-positive bacterium; defense response to protozoan; defense response to virus; symbiont-containing vacuole membrane,PF02263;PF02841;,,,,,,,,,GBP1_MOUSE,Mus musculus (Mouse),adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to interferon-gamma [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607] comp29117_c0_seq1,359,38.4401,0.92308409,3,40,,6.00E-10,Q6P698,Plastin-2 (L-plastin) (Lymphocyte cytosolic plastin 1),Plastin-2 (L-plastin) (Lymphocyte cytosolic plastin 1),GO:0005509; GO:0005737,calcium ion binding; cytoplasm,PF00307;PF13499;,,,,,,,,,PLSL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp29126_c0_seq1,291,42.9553,0.86252361,4,27,,7.00E-26,Q8AY68,SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) (p60Shc),SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) (p60Shc),GO:0005737; GO:0035556; GO:0040008,cytoplasm; intracellular signal transduction; regulation of growth,PF00640;PF00017;,1.00E-34,CHOYP_LOC100118291.1.1,,,,,,,SHC1_XENLA,Xenopus laevis (African clawed frog),angiogenesis [GO:0001525]; intracellular signal transduction [GO:0035556]; regulation of growth [GO:0040008] comp29129_c0_seq1,249,40.9639,0.38462159,5,24,,4.00E-11,E1BD52,Transmembrane protein 245,Transmembrane protein 245,GO:0016021,integral to membrane,PF01594;,,,,,,,,,TM245_BOVIN,Bos taurus (Bovine), comp29135_c0_seq1,308,44.4805,0.52911517,6,31,,2.00E-10,Q7LFX5,Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST),GO:0050656; GO:0000139; GO:0050659; GO:0030206; GO:0019319; GO:0016021,3'-phosphoadenosine 5'-phosphosulfate binding; Golgi membrane; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; chondroitin sulfate biosynthetic process; hexose biosynthetic process; integral to membrane,,,,,,,,,,CHSTF_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319] comp29154_c0_seq1,316,42.0886,0.65137639,1,45,,3.00E-16,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp29171_c0_seq1,477,44.2348,0.51872176,2,45,,8.00E-49,P97524,"Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)","Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)",GO:0005524; GO:0005788; GO:0005789; GO:0005779; GO:0004467; GO:0031957,ATP binding; endoplasmic reticulum lumen; endoplasmic reticulum membrane; integral to peroxisomal membrane; long-chain fatty acid-CoA ligase activity; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,1.00E-35,CHOYP_BRAFLDRAFT_102226.1.1,,,,,,,S27A2_RAT,Rattus norvegicus (Rat),fatty acid transport [GO:0015908]; long-chain fatty acid metabolic process [GO:0001676] comp29172_c1_seq1,208,42.3077,0.33000763,0,35,,5.00E-08,Q63634,Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor),Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor),GO:0003214; GO:0005737; GO:0042755; GO:0060112; GO:0016021; GO:0043066; GO:0014050; GO:0032229; GO:0003151; GO:0001602; GO:0001601; GO:0005886; GO:0002675; GO:0048661,"cardiac left ventricle morphogenesis; cytoplasm; eating behavior; generation of ovulation cycle rhythm; integral to membrane; negative regulation of apoptotic process; negative regulation of glutamate secretion; negative regulation of synaptic transmission, GABAergic; outflow tract morphogenesis; pancreatic polypeptide receptor activity; peptide YY receptor activity; plasma membrane; positive regulation of acute inflammatory response; positive regulation of smooth muscle cell proliferation",PF00001;,,,,,,,,,NPY5R_RAT,Rattus norvegicus (Rat),"aging [GO:0007568]; cardiac left ventricle morphogenesis [GO:0003214]; cell surface receptor signaling pathway [GO:0007166]; chemical synaptic transmission [GO:0007268]; eating behavior [GO:0042755]; generation of ovulation cycle rhythm [GO:0060112]; negative regulation of acute inflammatory response to antigenic stimulus [GO:0002865]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; outflow tract morphogenesis [GO:0003151]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of smooth muscle cell proliferation [GO:0048661]" comp29201_c0_seq1,315,42.5397,1.03753391,1,30,,4.00E-17,P54923,[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme),GO:0003875; GO:0006464; GO:0000287; GO:0051725,ADP-ribosylarginine hydrolase activity; cellular protein modification process; magnesium ion binding; protein de-ADP-ribosylation,PF03747;,,,,,,,,,ADPRH_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725] comp2920_c0_seq1,221,60.181,1.02970568,0,8,,4.00E-10,Q1J1X6,Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,,,,,,,,,PURA_DEIGD,Deinococcus geothermalis (strain DSM 11300),'de novo' AMP biosynthetic process [GO:0044208] comp2920_c1_seq1,256,60.1562,1.31841957,0,4,,3.00E-42,Q6A6A3,Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,,,,,,,,,PURA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' AMP biosynthetic process [GO:0044208] comp29237_c0_seq1,502,64.741,0.82870061,0,67,,3.00E-82,Q42690,"Fructose-bisphosphate aldolase 1, chloroplastic (EC 4.1.2.13)","Fructose-bisphosphate aldolase 1, chloroplastic (EC 4.1.2.13)",GO:0009507; GO:0004332; GO:0006096,chloroplast; fructose-bisphosphate aldolase activity; glycolysis,PF00274;,7.00E-15,CHOYP_LOC101487903.1.1,,,,,,,ALFC_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),glycolytic process [GO:0006096] comp29289_c0_seq1,386,43.7824,0.28624452,11,41,,1.00E-24,Q9DGG6,Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9),Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9),GO:0005524; GO:0004016; GO:0016021; GO:0035556; GO:0046872,ATP binding; adenylate cyclase activity; integral to membrane; intracellular signal transduction; metal ion binding,PF00211;,8.00E-32,CHOYP_APLD.1.1,,,,,,,ADCY9_CHICK,Gallus gallus (Chicken),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933] comp2929_c0_seq1,260,41.1538,0.82946142,1,5,,4.00E-08,Q9NP73,Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (EC 2.4.1.141) (EC 3.4.19.12) (Asparagine-linked glycosylation 13 homolog) (Glycosyltransferase 28 domain-containing protein 1) (UDP-N-acetylglucosamine transferase subunit ALG13 homolog),Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (EC 2.4.1.141) (EC 3.4.19.12) (Asparagine-linked glycosylation 13 homolog) (Glycosyltransferase 28 domain-containing protein 1) (UDP-N-acetylglucosamine transferase subunit ALG13 homolog),GO:0004577; GO:0030246; GO:0008234; GO:0006488; GO:0005789; GO:0030259; GO:0043687; GO:0018279; GO:0006508,N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity; carbohydrate binding; cysteine-type peptidase activity; dolichol-linked oligosaccharide biosynthetic process; endoplasmic reticulum membrane; lipid glycosylation; post-translational protein modification; protein N-linked glycosylation via asparagine; proteolysis,PF04101;PF02338;,,,,,,,,,ALG13_HUMAN,Homo sapiens (Human),dolichol-linked oligosaccharide biosynthetic process [GO:0006488] comp29305_c0_seq1,1078,41.3729,1.22395179,39,72,,2.00E-07,Q14BI2,Metabotropic glutamate receptor 2 (mGluR2),Metabotropic glutamate receptor 2 (mGluR2),GO:0030424; GO:0005246; GO:0030054; GO:0030425; GO:0014047; GO:0001641; GO:0016021; GO:0005622; GO:0043005; GO:0042734,axon; calcium channel regulator activity; cell junction; dendrite; glutamate secretion; group II metabotropic glutamate receptor activity; integral to membrane; intracellular; neuron projection; presynaptic membrane,PF00003;PF01094;PF07562;,,,,,,,,,GRM2_MOUSE,Mus musculus (Mouse),"glutamate secretion [GO:0014047]; regulation of synaptic transmission, glutamatergic [GO:0051966]" comp29306_c0_seq1,445,50.1124,0.25607085,7,50,,9.00E-26,O75095,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07645;PF00053;,,,,,,,,,MEGF6_HUMAN,Homo sapiens (Human), comp29313_c0_seq2,378,42.0635,0.55826905,3,45,,3.00E-32,O60292,Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3),Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3),GO:0005096; GO:0043547; GO:0051056,GTPase activator activity; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction,PF02145;PF11881;,3.00E-50,CHOYP_SI1L1.2.2,,,,,,,SI1L3_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell polarity [GO:0090162]; eye development [GO:0001654]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of small GTPase mediated signal transduction [GO:0051056] comp29317_c0_seq1,1208,43.957,0.55772152,30,115,,,,,,,,,6.00E-20,CHOYP_BRAFLDRAFT_124696.2.3,3.00E-15,ruditapes_c27447,,,,,,, comp29325_c0_seq1,524,44.2748,0.84710259,15,0,,3.00E-19,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp29351_c0_seq1,433,37.6443,0.59615703,8,46,,6.00E-07,Q4R6D9,Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1),Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1),GO:0032886,regulation of microtubule-based process,PF01875;,,,,,,,,,MEMO1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),regulation of microtubule-based process [GO:0032886] comp29355_c0_seq1,639,46.6354,0.37482634,16,47,,1.00E-52,Q9BZC7,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0043190; GO:0042626; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0006629; GO:0005765; GO:0005764; GO:0005815; GO:0032383; GO:0006357; GO:0042493; GO:0048545,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lipid metabolic process; lysosomal membrane; lysosome; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus",PF00005;,,,,,,,,,ABCA2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp29392_c0_seq1,265,47.9245,0.73114484,9,27,,1.00E-10,Q9P215,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,,,,,,,,,POGK_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp29399_c0_seq1,221,52.4887,0.61610882,0,37,,2.00E-16,Q9LEV3,"CBS domain-containing protein CBSX3, mitochondrial","CBS domain-containing protein CBSX3, mitochondrial",GO:0030554; GO:0045454; GO:0050897; GO:0005739; GO:0009651,adenyl nucleotide binding; cell redox homeostasis; cobalt ion binding; mitochondrion; response to salt stress,PF00571;,,,,,,,,,CBSX3_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell redox homeostasis [GO:0045454]; response to salt stress [GO:0009651] comp29422_c0_seq1,841,33.8882,0.54054397,152,1477,,,,,,,,,7.00E-11,CHOYP_contig_036710,,,,,,,,, comp29428_c0_seq1,253,37.1542,1.51958195,2,39,,2.00E-11,Q5DRD8,Protocadherin beta-11 (PCDH-beta-11),Protocadherin beta-11 (PCDH-beta-11),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;,,,,,,,,,PCDBB_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp29439_c0_seq1,444,47.0721,0.49307729,17,26,,3.00E-14,Q91X43,SH3 domain-containing protein 19 (Kryn),SH3 domain-containing protein 19 (Kryn),GO:0005737; GO:0007010; GO:0022604,cytoplasm; cytoskeleton organization; regulation of cell morphogenesis,PF00018;PF07653;PF14604;,,,,,,,,,SH319_MOUSE,Mus musculus (Mouse),cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604] comp29440_c0_seq1,304,44.4079,0.9561232,1,38,,2.00E-14,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp29442_c0_seq1,253,45.0593,1.1029949,0,36,,3.00E-17,Q24524,Protein singed,Protein singed,GO:0015629; GO:0051015; GO:0048800; GO:0008407; GO:0035017; GO:0005737; GO:0016358; GO:0007163; GO:0046847; GO:0035099; GO:0035317; GO:0030034; GO:0043005; GO:0048812; GO:0043025; GO:0048477; GO:0042060,actin cytoskeleton; actin filament binding; antennal morphogenesis; chaeta morphogenesis; cuticle pattern formation; cytoplasm; dendrite development; establishment or maintenance of cell polarity; filopodium assembly; hemocyte migration; imaginal disc-derived wing hair organization; microvillar actin bundle assembly; neuron projection; neuron projection morphogenesis; neuronal cell body; oogenesis; wound healing,PF06268;,,,,,,,,,SING_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060] comp29451_c0_seq1,445,46.0674,0.69120845,9,38,,2.00E-39,Q32PH0,Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein),Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein),GO:0005794; GO:0030154; GO:0005783,Golgi apparatus; cell differentiation; endoplasmic reticulum,PF08626;,3.00E-13,CHOYP_TRAPPC9.1.1,,,,,,,TPPC9_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154] comp29464_c0_seq1,758,43.1398,0.32141263,13,77,,2.00E-131,Q9NRD5,PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein),PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein),GO:0016887; GO:0043045; GO:0043046; GO:0005794; GO:0030054; GO:0030666; GO:0046872; GO:0005739; GO:0015844; GO:0045161; GO:0048471; GO:0042734; GO:0005080; GO:0007205; GO:0006468; GO:0006605; GO:0005102; GO:0043113; GO:0006890; GO:0007268,"ATPase activity; DNA methylation involved in embryo development; DNA methylation involved in gamete generation; Golgi apparatus; cell junction; endocytic vesicle membrane; metal ion binding; mitochondrion; monoamine transport; neuronal ion channel clustering; perinuclear region of cytoplasm; presynaptic membrane; protein kinase C binding; protein kinase C-activating G-protein coupled receptor signaling pathway; protein phosphorylation; protein targeting; receptor binding; receptor clustering; retrograde vesicle-mediated transport, Golgi to ER; synaptic transmission",PF06456;PF00595;,6.00E-157,CHOYP_LOC100370426.1.2,,,,,,,PICK1_HUMAN,Homo sapiens (Human),"cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; glial cell development [GO:0021782]; long term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neuronal ion channel clustering [GO:0045161]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; receptor clustering [GO:0043113]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp29472_c0_seq1,587,37.6491,0.55263318,5,56,,8.00E-19,Q9BUY5,Zinc finger protein 426,Zinc finger protein 426,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN426_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp29475_c0_seq1,272,45.2206,1.10916992,2,24,,2.00E-07,Q54KZ0,TM2 domain-containing protein DDB_G0287015,TM2 domain-containing protein DDB_G0287015,GO:0016021,integral to membrane,PF05154;,,,,,,,,,TM2D3_DICDI,Dictyostelium discoideum (Slime mold), comp29483_c0_seq1,404,36.8812,0.36685007,8,18,,4.00E-36,Q8BTX9,Inactive hydroxysteroid dehydrogenase-like protein 1,Inactive hydroxysteroid dehydrogenase-like protein 1,GO:0005739; GO:0055114; GO:0016491,mitochondrion; oxidation-reduction process; oxidoreductase activity,PF00106;,3.00E-44,CHOYP_LOC100371253.1.1,,,,,,,HSDL1_MOUSE,Mus musculus (Mouse), comp29485_c0_seq1,567,41.7989,0.97469201,3,58,,6.00E-13,P07451,Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III),Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III),GO:0015701; GO:0004089; GO:0005829; GO:0016151; GO:0006730; GO:0006979; GO:0044281; GO:0008270,bicarbonate transport; carbonate dehydratase activity; cytosol; nickel cation binding; one-carbon metabolic process; response to oxidative stress; small molecule metabolic process; zinc ion binding,PF00194;,,,,,,,,,CAH3_HUMAN,Homo sapiens (Human),bicarbonate transport [GO:0015701]; one-carbon metabolic process [GO:0006730]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979] comp29497_c0_seq1,380,38.4211,0.99698758,0,45,,,,,,,,,9.00E-31,CHOYP_contig_009415,,,,,,,,, comp29498_c0_seq1,687,40.6114,0.39928332,7,73,,1.00E-85,O35509,Ras-related protein Rab-11B,Ras-related protein Rab-11B,GO:0019003; GO:0005525; GO:0003924; GO:0030054; GO:0006928; GO:0071468; GO:0045054; GO:0035773; GO:0032402; GO:0005739; GO:0045335; GO:0030670; GO:0001881; GO:0055037; GO:0055038; GO:0045055; GO:0044070; GO:2001135; GO:2000008; GO:1990126; GO:0007264; GO:0008021; GO:0030672; GO:0033572,"GDP binding; GTP binding; GTPase activity; cell junction; cellular component movement; cellular response to acidity; constitutive secretory pathway; insulin secretion involved in cellular response to glucose stimulus; melanosome transport; mitochondrion; phagocytic vesicle; phagocytic vesicle membrane; receptor recycling; recycling endosome; recycling endosome membrane; regulated secretory pathway; regulation of anion transport; regulation of endocytic recycling; regulation of protein localization to cell surface; retrograde transport, endosome to plasma membrane; small GTPase mediated signal transduction; synaptic vesicle; synaptic vesicle membrane; transferrin transport",PF00071;,3.00E-58,CHOYP_RB11B.1.1,,,,,,,RB11B_RAT,Rattus norvegicus (Rat),"cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; establishment of protein localization to membrane [GO:0090150]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]" comp29507_c0_seq1,439,52.164,1.22279467,1,74,,,,,,,,,2.00E-15,CHOYP_PHUM_PHUM377430.2.2,,,,,,,,, comp29529_c0_seq1,284,35.2113,0.23399305,6,42,,3.00E-14,Q3U288,Zinc finger protein 710,Zinc finger protein 710,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZN710_MOUSE,Mus musculus (Mouse),"regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp29560_c0_seq1,267,39.3258,0.69482456,3,60,,2.00E-11,Q28G88,Fez family zinc finger protein 2,Fez family zinc finger protein 2,GO:0003677; GO:0030154; GO:0046872; GO:0007399; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell differentiation; metal ion binding; nervous system development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,FEZF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"axon guidance [GO:0007411]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp29582_c0_seq1,432,40.5093,0.79200842,5,62,,1.00E-21,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp29583_c0_seq1,465,36.5591,1.05669423,50,0,,1.00E-06,O66112,Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1),Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1),GO:0006096; GO:0043231; GO:0004739,glycolysis; intracellular membrane-bounded organelle; pyruvate dehydrogenase (acetyl-transferring) activity,PF00676;,,,,,,,,,ODPA_ZYMMO,Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4),acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] comp29602_c0_seq1,474,42.616,1.23797664,2,73,,6.00E-12,Q4ZJM9,Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11),GO:0005581,collagen,PF00386;,,,,,,,,,C1QL4_MOUSE,Mus musculus (Mouse),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] comp29603_c0_seq1,1044,35.6322,0.31127158,38,137,,3.00E-07,P15924,Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen),Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen),GO:0034332; GO:0016323; GO:0086069; GO:0016337; GO:0006921; GO:0001533; GO:0030057; GO:0002934; GO:0014704; GO:0005882; GO:0045109; GO:0030216; GO:0005739; GO:0018149; GO:0005886; GO:0030674; GO:0071896; GO:0086091; GO:0086005; GO:0005200; GO:0003223,"adherens junction organization; basolateral plasma membrane; bundle of His cell to Purkinje myocyte communication; cell-cell adhesion; cellular component disassembly involved in execution phase of apoptosis; cornified envelope; desmosome; desmosome organization; intercalated disc; intermediate filament; intermediate filament organization; keratinocyte differentiation; mitochondrion; peptide cross-linking; plasma membrane; protein binding, bridging; protein localization to adherens junction; regulation of heart rate by cardiac conduction; regulation of ventricular cardiac muscle cell action potential; structural constituent of cytoskeleton; ventricular compact myocardium morphogenesis",PF00681;,3.00E-23,CHOYP_LOC100881043.1.1,,,,,,,DESP_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; desmosome organization [GO:0002934]; epidermis development [GO:0008544]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to adherens junction [GO:0071896]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060] comp29614_c0_seq1,325,39.3846,0.63688027,3,13,,5.00E-32,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp29615_c0_seq1,312,38.7821,1.65012794,6,68,,2.00E-07,P02693,"Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty acid-binding protein) (I-FABP)","Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty acid-binding protein) (I-FABP)",GO:0045179; GO:0005504; GO:0006631; GO:0050892; GO:0005324; GO:0005902; GO:0005886,apical cortex; fatty acid binding; fatty acid metabolic process; intestinal absorption; long-chain fatty acid transporter activity; microvillus; plasma membrane,PF00061;,,,,,,,,,FABPI_RAT,Rattus norvegicus (Rat),fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909] comp29623_c0_seq2,805,29.1925,1.11019455,52,48,,,,,,,,,2.00E-11,CHOYP_contig_011432,,,,,,,,, comp296_c0_seq1,202,62.3762,1.73149759,0,3,,1.00E-11,P59966,Replicative DNA helicase (EC 3.6.4.12) [Cleaved into: Endonuclease PI-MboHIP (EC 3.1.-.-) (Mbo dnaB intein)],Replicative DNA helicase (EC 3.6.4.12) [Cleaved into: Endonuclease PI-MboHIP (EC 3.1.-.-) (Mbo dnaB intein)],GO:0005524; GO:0003677; GO:0032508; GO:0003678; GO:0006269; GO:0004519; GO:0016539; GO:0006314; GO:0090305; GO:1990077,"ATP binding; DNA binding; DNA duplex unwinding; DNA helicase activity; DNA replication, synthesis of RNA primer; endonuclease activity; intein-mediated protein splicing; intron homing; nucleic acid phosphodiester bond hydrolysis; primosome complex",PF00772;PF03796;PF14528;,,,,,,,,,DNAB_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),"DNA replication, synthesis of RNA primer [GO:0006269]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]" comp29746_c0_seq1,248,52.8226,1.05212978,40,32,,,,,,,,,9.00E-92,CHOYP_LOC100353582.2.2,,,,,,,,, comp29761_c0_seq1,299,40.8027,0.16194513,6,41,,,,,,,,,2.00E-12,CHOYP_MYO1B.1.1,,,,,,,,, comp29767_c0_seq2,515,41.5534,0.67894993,10,14,,1.00E-12,Q63789,Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),GO:0046935; GO:0005942,1-phosphatidylinositol-3-kinase regulator activity; phosphatidylinositol 3-kinase complex,PF16454;PF00017;,,,,,,,,,P55G_RAT,Rattus norvegicus (Rat),insulin receptor signaling pathway [GO:0008286]; positive regulation of glucose import in response to insulin stimulus [GO:2001275] comp29778_c0_seq1,1048,37.6908,0.6196903,36,57,,3.00E-51,Q920F5,"Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)","Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)",GO:0006085; GO:0005829; GO:0006633; GO:0019395; GO:2001294; GO:0050080; GO:0005759; GO:0005782; GO:0005777; GO:0046321; GO:0031998; GO:0010906; GO:0002931,acetyl-CoA biosynthetic process; cytosol; fatty acid biosynthetic process; fatty acid oxidation; malonyl-CoA catabolic process; malonyl-CoA decarboxylase activity; mitochondrial matrix; peroxisomal matrix; peroxisome; positive regulation of fatty acid oxidation; regulation of fatty acid beta-oxidation; regulation of glucose metabolic process; response to ischemia,PF05292;,4.00E-22,CHOYP_PHUM_PHUM479110.1.1,,,,,,,DCMC_RAT,Rattus norvegicus (Rat),acetyl-CoA biosynthetic process [GO:0006085]; fatty acid biosynthetic process [GO:0006633]; fatty acid oxidation [GO:0019395]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose metabolic process [GO:0010906]; response to ischemia [GO:0002931] comp29788_c0_seq1,298,41.9463,0.61713801,0,43,,2.00E-25,Q9GP38,Probable mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI),Probable mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI),GO:0009298; GO:0005975; GO:0005737; GO:0004476; GO:0008270,GDP-mannose biosynthetic process; carbohydrate metabolic process; cytoplasm; mannose-6-phosphate isomerase activity; zinc ion binding,PF01238;,,,,,,,,,MPI_ECHMU,Echinococcus multilocularis (Fox tapeworm),carbohydrate metabolic process [GO:0005975]; GDP-mannose biosynthetic process [GO:0009298] comp29823_c0_seq1,302,46.6887,0.12198201,9,62,,4.00E-08,P55265,Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP),Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP),GO:0003677; GO:0003723; GO:0006382; GO:0005737; GO:0051607; GO:0003726; GO:0010467; GO:0031047; GO:0016556; GO:0006397; GO:0046872; GO:0043066; GO:0044387; GO:0005730; GO:0005654; GO:0005634; GO:0045070; GO:0006611; GO:0006606; GO:0035455; GO:0009615; GO:0044530; GO:0060337,DNA binding; RNA binding; adenosine to inosine editing; cytoplasm; defense response to virus; double-stranded RNA adenosine deaminase activity; gene expression; gene silencing by RNA; mRNA modification; mRNA processing; metal ion binding; negative regulation of apoptotic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; nucleoplasm; nucleus; positive regulation of viral genome replication; protein export from nucleus; protein import into nucleus; response to interferon-alpha; response to virus; supraspliceosomal complex; type I interferon-mediated signaling pathway,PF02137;PF00035;PF02295;,,,,,,,,,DSRAD_HUMAN,Homo sapiens (Human),adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337] comp29827_c0_seq1,207,45.8937,0.73760587,0,38,,,,,,,,,6.00E-11,CHOYP_BRAFLDRAFT_127065.6.7,,,,,,,,, comp29842_c0_seq1,692,41.185,0.4521238,33,50,,8.00E-58,P92208,Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket),Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket),GO:0005524; GO:0004705; GO:0016055; GO:0019731; GO:0030424; GO:0048675; GO:0007411; GO:0007298; GO:0071243; GO:0071276; GO:0034614; GO:0048674; GO:0005737; GO:0030425; GO:0071907; GO:0046843; GO:0007391; GO:0048615; GO:0043652; GO:0001736; GO:0046529; GO:0048803; GO:0035006; GO:0046844; GO:0043508; GO:0010508; GO:0009408; GO:0035313,"ATP binding; JUN kinase activity; Wnt receptor signaling pathway; antibacterial humoral response; axon; axon extension; axon guidance; border follicle cell migration; cellular response to arsenic-containing substance; cellular response to cadmium ion; cellular response to reactive oxygen species; collateral sprouting of injured axon; cytoplasm; dendrite; determination of digestive tract left/right asymmetry; dorsal appendage formation; dorsal closure; embryonic anterior midgut (ectodermal) morphogenesis; engulfment of apoptotic cell; establishment of planar polarity; imaginal disc fusion, thorax closure; imaginal disc-derived male genitalia morphogenesis; melanization defense response; micropyle formation; negative regulation of JUN kinase activity; positive regulation of autophagy; response to heat; wound healing, spreading of epidermal cells",PF00069;,2.00E-67,CHOYP_JNK.1.1,,,,,,,JNK_DROME,Drosophila melanogaster (Fruit fly),"antibacterial humoral response [GO:0019731]; axon extension [GO:0048675]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; collateral sprouting of injured axon [GO:0048674]; defense response [GO:0006952]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; engulfment of apoptotic cell [GO:0043652]; establishment of planar polarity [GO:0001736]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc fusion, thorax closure [GO:0046529]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; long-term memory [GO:0007616]; MAPK cascade [GO:0000165]; melanization defense response [GO:0035006]; micropyle formation [GO:0046844]; mushroom body development [GO:0016319]; negative regulation of JUN kinase activity [GO:0043508]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; ovarian follicle cell development [GO:0030707]; positive regulation of autophagy [GO:0010508]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of neuron remodeling [GO:1904801]; protein phosphorylation [GO:0006468]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060]; wound healing, spreading of epidermal cells [GO:0035313]" comp29867_c0_seq1,248,43.9516,0.34016947,3,19,,2.00E-11,Q8K358,Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U),Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U),GO:0006506; GO:0042765,GPI anchor biosynthetic process; GPI-anchor transamidase complex,PF06728;,,,,,,,,,PIGU_MOUSE,Mus musculus (Mouse),attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; regulation of JAK-STAT cascade [GO:0046425] comp29954_c0_seq1,459,47.4946,0.54209012,13,21,,7.00E-18,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp29959_c0_seq1,205,46.3415,0.37218591,7,19,,1.00E-22,Q3E811,Regulator of rDNA transcription protein 15,Regulator of rDNA transcription protein 15,GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",,4.00E-64,CHOYP_MTR_5G050970.1.1,,,,,,,RRT15_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp29961_c0_seq1,570,33.6842,0.64483541,7,85,,7.00E-08,B5FY93,UPF0184 protein C9orf16 homolog,UPF0184 protein C9orf16 homolog,,,PF03670;,,,,,,,,,CI016_TAEGU,Taeniopygia guttata (Zebra finch) (Poephila guttata), comp29984_c0_seq1,293,49.1468,0.29312405,4,34,,3.00E-40,Q99707,Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),GO:0034641; GO:0031419; GO:0009235; GO:0005829; GO:0008898; GO:0008705; GO:0032259; GO:0007399; GO:0042558; GO:0000096; GO:0006805; GO:0008270,cellular nitrogen compound metabolic process; cobalamin binding; cobalamin metabolic process; cytosol; homocysteine S-methyltransferase activity; methionine synthase activity; methylation; nervous system development; pteridine-containing compound metabolic process; sulfur amino acid metabolic process; xenobiotic metabolic process; zinc ion binding,PF02310;PF02607;PF02965;PF00809;PF02574;,5.00E-64,CHOYP_METH.1.1,,,,,,,METH_HUMAN,Homo sapiens (Human),axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; nervous system development [GO:0007399]; pteridine-containing compound metabolic process [GO:0042558]; response to axon injury [GO:0048678]; sulfur amino acid metabolic process [GO:0000096] comp30073_c1_seq1,301,45.8472,0.82618757,1,19,,,,,,,,,1.00E-20,CHOYP_LOC100374815.1.1,,,,,,,,, comp30095_c0_seq1,284,41.1972,0.58334057,3,35,,2.00E-12,Q96SC8,Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5),Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5),GO:0046872; GO:0005634; GO:0043565; GO:0003700; GO:0035914,metal ion binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation,PF00751;PF03474;,,,,,,,,,DMTA2_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; cerebral cortex regionalization [GO:0021796]; dopaminergic neuron differentiation [GO:0071542]; neuron fate specification [GO:0048665]; positive regulation of neuroblast proliferation [GO:0002052]; sex differentiation [GO:0007548]; skeletal muscle cell differentiation [GO:0035914] comp30107_c0_seq1,205,41.4634,0.68516043,0,28,,4.00E-22,Q9WTW7,Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1),Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1),GO:0008520; GO:0016324; GO:0009925; GO:0007420; GO:0005903; GO:0005737; GO:0033300; GO:0005887; GO:0043229; GO:0030324; GO:0009636; GO:0070890; GO:0070904,L-ascorbate:sodium symporter activity; apical plasma membrane; basal plasma membrane; brain development; brush border; cytoplasm; dehydroascorbic acid transporter activity; integral to plasma membrane; intracellular organelle; lung development; response to toxic substance; sodium-dependent L-ascorbate transmembrane transporter activity; transepithelial L-ascorbic acid transport,PF00860;,,,,,,,,,S23A1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904] comp30140_c0_seq1,623,44.3018,0.62813407,7,84,,,,,,,,,4.00E-13,CHOYP_LOC100708054.1.1,,,,,,,,, comp3014_c0_seq1,210,45.7143,0.27486511,1,4,,3.00E-11,Q8K078,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0006811; GO:0005886; GO:0005215,integral to membrane; ion transport; plasma membrane; transporter activity,PF07648;PF03137;,7.00E-16,CHOYP_SO4A1.1.1,,,,,,,SO4A1_MOUSE,Mus musculus (Mouse),organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp30167_c0_seq1,448,45.5357,0.57907035,7,47,,1.00E-27,Q28DE7,Kelch domain-containing protein 10,Kelch domain-containing protein 10,GO:0005737; GO:0005634,cytoplasm; nucleus,PF01344;,,,,,,,,,KLD10_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp30195_c0_seq1,201,58.7065,1.16836986,0,6,,8.00E-29,Q6A7L9,Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS),Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS),GO:0005524; GO:0002161; GO:0005737; GO:0004827; GO:0006433; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; proline-tRNA ligase activity; prolyl-tRNA aminoacylation; regulation of translational fidelity,PF03129;PF00587;PF04073;,,,,,,,,,SYP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),prolyl-tRNA aminoacylation [GO:0006433] comp30221_c0_seq1,238,43.2773,0.54692041,6,21,,3.00E-07,Q71MB6,Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),GO:0016323; GO:0030154; GO:0016021; GO:0006811; GO:0007275; GO:0007283; GO:0005215,basolateral plasma membrane; cell differentiation; integral to membrane; ion transport; multicellular organismal development; spermatogenesis; transporter activity,PF07648;PF03137;,2.00E-24,CHOYP_MYSP.9.9,,,,,,,SO4C1_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; sodium-independent organic anion transport [GO:0043252]; spermatogenesis [GO:0007283]; transport [GO:0006810] comp30239_c0_seq1,201,46.2687,0.77322488,0,17,,3.00E-12,P51175,Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4),Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4),GO:0006783; GO:0031304; GO:0004729; GO:0006782,heme biosynthetic process; intrinsic to mitochondrial inner membrane; oxygen-dependent protoporphyrinogen oxidase activity; protoporphyrinogen IX biosynthetic process,PF01593;,,,,,,,,,PPOX_MOUSE,Mus musculus (Mouse),heme biosynthetic process [GO:0006783]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to drug [GO:0042493] comp30247_c0_seq2,387,46.2532,0.69534514,2,0,,5.00E-22,Q497V6,Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1),Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1),GO:0003677; GO:0003682; GO:0005677; GO:0005694; GO:0031507; GO:0045892; GO:0006351,"DNA binding; chromatin binding; chromatin silencing complex; chromosome; heterochromatin assembly; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01426;,3.00E-12,CHOYP_ISCW_ISCW000975.1.1,,,,,,,BAHD1_MOUSE,Mus musculus (Mouse),"chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp30273_c0_seq1,236,31.7797,0.35532872,11,0,,2.00E-09,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp30328_c0_seq1,223,57.3991,1.25814496,1,6,,2.00E-39,Q8GBW6,Methylmalonyl-CoA carboxyltransferase 12S subunit (EC 2.1.3.1) (Transcarboxylase 12S subunit),Methylmalonyl-CoA carboxyltransferase 12S subunit (EC 2.1.3.1) (Transcarboxylase 12S subunit),GO:0003989; GO:0009317; GO:0006633; GO:0047154,acetyl-CoA carboxylase activity; acetyl-CoA carboxylase complex; fatty acid biosynthetic process; methylmalonyl-CoA carboxytransferase activity,PF01039;,,,,,,,,,12S_PROFR,Propionibacterium freudenreichii subsp. shermanii,fatty acid biosynthetic process [GO:0006633] comp30345_c0_seq1,205,36.5854,0.32339859,0,7,,1.00E-08,P27466,Calcium/calmodulin-dependent protein kinase I (EC 2.7.11.17),Calcium/calmodulin-dependent protein kinase I (EC 2.7.11.17),GO:0005524; GO:0004683; GO:0005737; GO:0007165,ATP binding; calmodulin-dependent protein kinase activity; cytoplasm; signal transduction,PF00069;,,,,,,,,,KCC1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] comp30348_c0_seq1,253,48.6166,0.34399237,13,12,,1.00E-26,Q6ZMW3,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,2.00E-12,CHOYP_EMAL6.1.1,,,,,,,EMAL6_HUMAN,Homo sapiens (Human), comp30355_c0_seq1,356,39.6067,0.43203245,10,9,,2.00E-38,Q5GN48,Dystrophin,Dystrophin,GO:0005509; GO:0030054; GO:0005737; GO:0005856; GO:0045211; GO:0042383; GO:0008270,calcium ion binding; cell junction; cytoplasm; cytoskeleton; postsynaptic membrane; sarcolemma; zinc ion binding,PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;,8.00E-25,CHOYP_DLP.1.1,,,,,,,DMD_PIG,Sus scrofa (Pig),muscle attachment [GO:0016203] comp30377_c0_seq1,315,43.8095,0.79714909,0,0,,3.00E-16,Q63164,"Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)","Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08393;PF03028;PF12777;,,,,,,,,,DYH1_RAT,Rattus norvegicus (Rat),cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317] comp30377_c0_seq2,336,44.9405,0.71474652,2,0,,3.00E-55,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-75,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp30390_c0_seq1,219,37.4429,0.79280932,2,7,,2.00E-21,Q96G23,Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Tumor metastasis-suppressor gene 1 protein),Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Tumor metastasis-suppressor gene 1 protein),GO:0046513; GO:0005789; GO:0016021; GO:0031965; GO:0043565; GO:0003700; GO:0044281; GO:0030148; GO:0050291,ceramide biosynthetic process; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; small molecule metabolic process; sphingolipid biosynthetic process; sphingosine N-acyltransferase activity,PF00046;PF03798;,1.00E-20,CHOYP_LOC100742830.1.1,,,,,,,CERS2_HUMAN,Homo sapiens (Human),ceramide biosynthetic process [GO:0046513]; negative regulation of axon regeneration [GO:0048681]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation involved in axon regeneration [GO:1905045]; sphingolipid biosynthetic process [GO:0030148] comp30429_c0_seq1,367,41.4169,0.38655749,13,10,,2.00E-12,O54829,Regulator of G-protein signaling 7 (RGS7),Regulator of G-protein signaling 7 (RGS7),GO:0007186; GO:0005096; GO:0005737; GO:0044292; GO:0005834; GO:0035556; GO:0005634; GO:0005886; GO:0008277; GO:0004871; GO:0038032,G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; dendrite terminus; heterotrimeric G-protein complex; intracellular signal transduction; nucleus; plasma membrane; regulation of G-protein coupled receptor protein signaling pathway; signal transducer activity; termination of G-protein coupled receptor signaling pathway,PF00610;PF00631;PF00615;,,,,,,,,,RGS7_MOUSE,Mus musculus (Mouse),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp30445_c0_seq1,282,58.156,0.71935713,0,14,,3.00E-09,Q9DEX7,Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(5)/Delta(6) fatty acid desaturase) (D5D/D6D fatty acid desaturase) (Delta-5/Delta-6 fatty acid desaturase),Fatty acid desaturase 2 (EC 1.14.19.3) (Acyl-CoA 6-desaturase) (Delta(5)/Delta(6) fatty acid desaturase) (D5D/D6D fatty acid desaturase) (Delta-5/Delta-6 fatty acid desaturase),GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0016717; GO:0006636,"endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; unsaturated fatty acid biosynthetic process",PF00173;PF00487;,,,,,,,,,FADS2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),liver development [GO:0001889]; unsaturated fatty acid biosynthetic process [GO:0006636] comp30473_c0_seq1,215,40.9302,0.11538711,4,0,,3.00E-18,Q7ZU91,"Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)","Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)",GO:0005524; GO:0047325; GO:0032957; GO:0052726; GO:0052725; GO:0005622; GO:0016853; GO:0000287,"ATP binding; inositol tetrakisphosphate 1-kinase activity; inositol trisphosphate metabolic process; inositol-1,3,4-trisphosphate 5-kinase activity; inositol-1,3,4-trisphosphate 6-kinase activity; intracellular; isomerase activity; magnesium ion binding",PF05770;,,,,,,,,,ITPK1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),inositol trisphosphate metabolic process [GO:0032957] comp30495_c0_seq1,264,30.6818,0.82299317,3,22,,,,,,,,,,,1.00E-17,ruditapes_c1813,,,,,,, comp30507_c0_seq1,224,58.9286,0.87811667,2,30,,3.00E-24,P0AB70,NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase subunit beta) (Pyridine nucleotide transhydrogenase subunit beta),NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase subunit beta) (Pyridine nucleotide transhydrogenase subunit beta),GO:0008750; GO:0050661; GO:0016021; GO:0005886,NAD(P)+ transhydrogenase (AB-specific) activity; NADP binding; integral to membrane; plasma membrane,PF02233;,,,,,,,,,PNTB_SHIFL,Shigella flexneri, comp30517_c0_seq1,313,43.4505,0.34704156,3,10,,2.00E-07,Q8BHC7,Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (mRHBDD1) (Rhomboid-like protein 4),Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (mRHBDD1) (Rhomboid-like protein 4),GO:0030433; GO:0006915; GO:0034644; GO:0034620; GO:0044322; GO:0030176; GO:0031293; GO:0005739; GO:0043066; GO:0045732; GO:0010954; GO:0051047; GO:0043687; GO:0004252; GO:0048515,ER-associated protein catabolic process; apoptotic process; cellular response to UV; cellular response to unfolded protein; endoplasmic reticulum quality control compartment; integral to endoplasmic reticulum membrane; membrane protein intracellular domain proteolysis; mitochondrion; negative regulation of apoptotic process; positive regulation of protein catabolic process; positive regulation of protein processing; positive regulation of secretion; post-translational protein modification; serine-type endopeptidase activity; spermatid differentiation,PF01694;,,,,,,,,,RHBL4_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515]" comp3052_c0_seq1,269,46.4684,0.3577156,5,0,,1.00E-06,Q6P158,Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57),Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57),GO:0005524; GO:0008026; GO:0046872; GO:0003676,ATP binding; ATP-dependent helicase activity; metal ion binding; nucleic acid binding,PF00270;PF04408;PF00271;PF07717;PF05773;PF00642;,,,,,,,,,DHX57_HUMAN,Homo sapiens (Human),RNA processing [GO:0006396] comp30563_c0_seq1,258,41.4729,0.27553605,8,3,,,,,,,,,2.00E-17,CHOYP_BRAFLDRAFT_124005.1.1,,,,,,,,, comp30587_c0_seq1,294,40.1361,0.25489926,4,56,,2.00E-06,A7SAZ1,UPF0669 protein v1g209471,UPF0669 protein v1g209471,GO:0005576,extracellular region,PF17065;,,,,,,,,,U669_NEMVE,Nematostella vectensis (Starlet sea anemone), comp30593_c0_seq1,277,40.4332,0.53616899,3,7,,8.00E-29,Q8NHY6,Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6),Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP28_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp30634_c0_seq1,285,44.5614,0.44000542,13,26,,2.00E-24,Q8CHN6,Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),GO:0016831; GO:0019752; GO:0006672; GO:0005789; GO:0097194; GO:0016021; GO:0030170; GO:0008117,carboxy-lyase activity; carboxylic acid metabolic process; ceramide metabolic process; endoplasmic reticulum membrane; execution phase of apoptosis; integral to membrane; pyridoxal phosphate binding; sphinganine-1-phosphate aldolase activity,PF00282;,9.00E-23,CHOYP_SGPL1.1.1,,,,,,,SGPL1_RAT,Rattus norvegicus (Rat),androgen metabolic process [GO:0008209]; apoptotic signaling pathway [GO:0097190]; ceramide metabolic process [GO:0006672]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; fatty acid metabolic process [GO:0006631]; fibroblast migration [GO:0010761]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; regulation of multicellular organism growth [GO:0040014]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]; sphingolipid catabolic process [GO:0030149]; vasculogenesis [GO:0001570] comp30662_c0_seq1,265,43.0189,0.65578746,4,18,,1.00E-37,Q29S22,Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47),Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47),GO:0005524; GO:0008026; GO:0003723; GO:0008380; GO:0008625; GO:0006397; GO:0005730; GO:0006364,ATP binding; ATP-dependent helicase activity; RNA binding; RNA splicing; extrinsic apoptotic signaling pathway via death domain receptors; mRNA processing; nucleolus; rRNA processing,PF00270;PF00271;,,,,,,,,,DDX47_BOVIN,Bos taurus (Bovine),extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] comp30679_c0_seq1,295,45.0847,0.60272186,13,4,,2.00E-07,Q4PRC6,Snaclec 7 (C-type lectin-like 7),Snaclec 7 (C-type lectin-like 7),GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,CLEC7_DABSI,Daboia siamensis (Eastern Russel's viper) (Daboia russelii siamensis), comp30705_c0_seq1,278,43.1655,1.16400736,4,0,,,,,,,,,1.00E-15,CHOYP_contig_033669,,,,,,,,, comp30740_c0_seq1,278,43.5252,0.76230495,14,0,,1.00E-08,Q8JHV9,Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp30741_c0_seq1,303,46.2046,0.44528629,9,0,,1.00E-24,Q17R13,Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Activated CDC42 kinase 2) (Tyrosine kinase non-receptor protein 2),Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Activated CDC42 kinase 2) (Tyrosine kinase non-receptor protein 2),GO:0005524; GO:0005912; GO:0030136; GO:0005905; GO:0030659; GO:0006897; GO:0005768; GO:0046872; GO:0004715; GO:0005634; GO:0018108; GO:0005886; GO:0004674,ATP binding; adherens junction; clathrin-coated vesicle; coated pit; cytoplasmic vesicle membrane; endocytosis; endosome; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleus; peptidyl-tyrosine phosphorylation; plasma membrane; protein serine/threonine kinase activity,PF09027;PF11555;PF07714;PF14604;,9.00E-30,CHOYP_TNK2.1.1,,,,,,,ACK1_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; cell migration [GO:0016477]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp30776_c0_seq1,372,30.6452,0.57473451,3,11,,2.00E-07,Q13478,Interleukin-18 receptor 1 (IL-18R-1) (IL-18R1) (CD218 antigen-like family member A) (CDw218a) (IL1 receptor-related protein) (IL-1Rrp) (IL1R-rp) (CD antigen CD218a),Interleukin-18 receptor 1 (IL-18R-1) (IL-18R1) (CD218 antigen-like family member A) (CDw218a) (IL1 receptor-related protein) (IL-1Rrp) (IL1R-rp) (CD antigen CD218a),GO:0045063; GO:0006955; GO:0016021; GO:0004908; GO:0042008; GO:0030101; GO:0005886; GO:0042346; GO:0032729; GO:0004872; GO:0007165,T-helper 1 cell differentiation; immune response; integral to membrane; interleukin-1 receptor activity; interleukin-18 receptor activity; natural killer cell activation; plasma membrane; positive regulation of NF-kappaB import into nucleus; positive regulation of interferon-gamma production; receptor activity; signal transduction,PF01582;,,,,,,,,,IL18R_HUMAN,Homo sapiens (Human),immune response [GO:0006955]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; signal transduction [GO:0007165]; T-helper 1 cell differentiation [GO:0045063] comp30827_c0_seq1,344,40.9884,0.51780026,6,36,,1.00E-13,A1L244,Phosphatidylinositide phosphatase SAC1-A (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein A),Phosphatidylinositide phosphatase SAC1-A (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein A),GO:0005789; GO:0016021; GO:0016791,endoplasmic reticulum membrane; integral to membrane; phosphatase activity,PF02383;,3.00E-29,CHOYP_SAC1.1.1,,,,,,,SAC1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),phosphatidylinositol dephosphorylation [GO:0046856] comp30836_c0_seq1,258,41.8605,0.38499278,3,19,,6.00E-11,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,,,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp30850_c0_seq1,605,45.2893,0.48596765,23,22,,2.00E-24,P25407,STI1-like protein (Fragment),STI1-like protein (Fragment),,,PF13181;,,,,,,,,,STI1L_PLAFA,Plasmodium falciparum, comp30861_c0_seq1,233,46.3519,0.89781912,0,25,,2.00E-15,P98063,Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP),Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP),GO:0005794; GO:0005509; GO:0051216; GO:0030154; GO:0005615; GO:0004222; GO:0001503; GO:0061036; GO:0005578; GO:0006508; GO:0008270,Golgi apparatus; calcium ion binding; cartilage development; cell differentiation; extracellular space; metalloendopeptidase activity; ossification; positive regulation of cartilage development; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF01400;PF00431;PF07645;,1.00E-20,CHOYP_LOC100643173.2.2,1.00E-23,ruditapes2_c2239,,,,,BMP1_MOUSE,Mus musculus (Mouse),BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell development [GO:0048468]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395] comp30878_c0_seq1,355,36.338,0.34479692,16,6,,7.00E-30,Q5FWL7,Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15 homolog) (DHHC-15),Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15 homolog) (DHHC-15),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,2.00E-39,CHOYP_BRAFLDRAFT_117157.3.3,,,,,,,ZDH15_XENLA,Xenopus laevis (African clawed frog), comp30887_c0_seq1,207,45.8937,0.8642861,0,25,,4.00E-14,Q6DN14,Multiple C2 and transmembrane domain-containing protein 1,Multiple C2 and transmembrane domain-containing protein 1,GO:0005509; GO:0019722; GO:0016021,calcium ion binding; calcium-mediated signaling; integral to membrane,PF00168;PF08372;,8.00E-22,CHOYP_LOC100748072.1.1,,,,,,,MCTP1_HUMAN,Homo sapiens (Human),calcium-mediated signaling [GO:0019722] comp30914_c0_seq1,291,41.5808,0.39956684,5,13,,3.00E-07,Q66HW4,Lysosomal protein NCU-G1,Glycosylated lysosomal membrane protein (Lysosomal protein NCU-G1),GO:0016021; GO:0005765; GO:0005764,integral to membrane; lysosomal membrane; lysosome,PF15065;,,,,,,,,,NCUG1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp3091_c0_seq1,269,47.9554,0.86667864,3,7,,1.00E-21,Q6Q4G4,Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE),Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE),GO:0004180; GO:0005615; GO:0016020; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; extracellular space; membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,,,,,,,,,ACE_THETS,Theromyzon tessulatum (Duck leech), comp30923_c0_seq1,389,46.0154,0.68421505,8,7,,3.00E-54,O43795,Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa),Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa),GO:0005524; GO:0051017; GO:0030048; GO:0005903; GO:0005737; GO:0030175; GO:0000146; GO:0016459; GO:0005547; GO:0005546; GO:0005886,"ATP binding; actin filament bundle assembly; actin filament-based movement; brush border; cytoplasm; filopodium; microfilament motor activity; myosin complex; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane",PF00612;PF00063;PF06017;,2.00E-39,CHOYP_MYO1B.1.1,,,,,,,MYO1B_HUMAN,Homo sapiens (Human),actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; post-Golgi vesicle-mediated transport [GO:0006892] comp30991_c0_seq1,317,49.5268,0.31642106,14,0,,1.00E-22,Q9JIL5,Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF07525;PF01167;,2.00E-39,CHOYP_DPSE_GA18988.1.1,,,,,,,TULP4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567] comp31008_c0_seq1,423,51.3002,0.72219787,11,21,,6.00E-57,Q5HZQ9,Pecanex-like protein 4,Pecanex-like protein 4 (Pecanex homolog protein 4),GO:0016021,integral to membrane,PF05041;,7.00E-39,CHOYP_LOC100376367.1.1,,,,,,,PCX4_XENLA,Xenopus laevis (African clawed frog), comp31031_c0_seq1,244,48.3607,0.70708258,9,2,,2.00E-07,Q92823,Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related),Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related),GO:0001525; GO:0030506; GO:0007411; GO:0043194; GO:0007413; GO:0016337; GO:0007417; GO:0045162; GO:0009897; GO:0034113; GO:0005887; GO:0001764; GO:0019227; GO:0045666; GO:0008104; GO:0030516; GO:0031290; GO:0045202; GO:0007416,angiogenesis; ankyrin binding; axon guidance; axon initial segment; axonal fasciculation; cell-cell adhesion; central nervous system development; clustering of voltage-gated sodium channels; external side of plasma membrane; heterotypic cell-cell adhesion; integral to plasma membrane; neuron migration; neuronal action potential propagation; positive regulation of neuron differentiation; protein localization; regulation of axon extension; retinal ganglion cell axon guidance; synapse; synapse assembly,PF13882;PF00041;PF07679;,,,,,,,,,NRCAM_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; clustering of voltage-gated sodium channels [GO:0045162]; heterotypic cell-cell adhesion [GO:0034113]; neuronal action potential propagation [GO:0019227]; neuron migration [GO:0001764]; positive regulation of neuron differentiation [GO:0045666]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; retinal ganglion cell axon guidance [GO:0031290]; single organismal cell-cell adhesion [GO:0016337]; synapse assembly [GO:0007416] comp31033_c0_seq1,470,41.2766,0.50493368,3,4,,2.00E-32,Q6NUT3,Major facilitator superfamily domain-containing protein 12,Major facilitator superfamily domain-containing protein 12,GO:0016021; GO:0005765; GO:0006810,integral to membrane; lysosomal membrane; transport,,2.00E-22,CHOYP_LOC101158385.1.1,,,,,,,MFS12_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp3103_c0_seq1,333,51.952,0.35808417,2,0,,2.00E-30,Q502W6,von Willebrand factor A domain-containing protein 3B,von Willebrand factor A domain-containing protein 3B,,,PF15057;PF13768;,3.00E-62,CHOYP_BRAFLDRAFT_117157.3.3,,,,,,,VWA3B_HUMAN,Homo sapiens (Human), comp31078_c0_seq1,221,38.914,0.48052932,5,9,,5.00E-23,Q8TCX5,Rhophilin-1 (GTP-Rho-binding protein 1),Rhophilin-1 (GTP-Rho-binding protein 1),GO:0007165; GO:0005083,signal transduction; small GTPase regulator activity,PF03097;PF02185;PF00595;,2.00E-18,CHOYP_LOC580747.1.1,,,,,,,RHPN1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp31101_c0_seq1,318,42.7673,0.29435124,9,0,,6.00E-37,Q8VEJ1,GPN-loop GTPase 2 (ATP-binding domain 1 family member B),GPN-loop GTPase 2 (ATP-binding domain 1 family member B),GO:0005525,GTP binding,PF03029;,6.00E-32,CHOYP_GPN2.1.1,,,,,,,GPN2_MOUSE,Mus musculus (Mouse), comp31120_c0_seq1,227,44.0529,0.18247653,2,0,,2.00E-22,Q5ZIT8,Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150),GO:0008237; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"metallopeptidase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01433;,,,,,,,,,TAF2_CHICK,Gallus gallus (Chicken),positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp31124_c0_seq1,236,31.3559,0.87133917,7,2,,,,,,,,,2.00E-16,CHOYP_LOC100537145.2.3,,,,,,,,, comp31154_c0_seq1,261,33.7165,0.27991864,9,0,,1.00E-09,P10401,Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0090305,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00665;PF00078;,,,,,,,,,POLY_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp31156_c0_seq1,274,63.1387,1.2857707,6,11,,8.00E-16,Q8CZD5,Glucose-specific phosphotransferase enzyme IIA component (EC 2.7.1.-) (EIIA-Glc) (EIII-Glc) (PTS system glucose-specific EIIA component),PTS system glucose-specific EIIA component (EIIA-Glc) (EIII-Glc) (Glucose-specific phosphotransferase enzyme IIA component) (EC 2.7.1.199),GO:0005737; GO:0016301; GO:0016020; GO:0009401; GO:0005351,cytoplasm; kinase activity; membrane; phosphoenolpyruvate-dependent sugar phosphotransferase system; sugar:hydrogen symporter activity,PF00358;,,,,,,,,,PTGA_OCEIH,Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831),phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401] comp31178_c0_seq1,261,50.5747,1.21664196,0,16,,6.00E-14,Q8BXB6,Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9),Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9),GO:0016021; GO:0006811; GO:0005886; GO:0005215,integral to membrane; ion transport; plasma membrane; transporter activity,PF03137;,,,,,,,,,SO2B1_MOUSE,Mus musculus (Mouse),bile acid and bile salt transport [GO:0015721]; organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252] comp31181_c0_seq1,265,40.7547,0.54808473,6,0,,,,,,,,,3.00E-15,CHOYP_KLC.1.3,,,,,,,,, comp31181_c0_seq2,211,39.3365,0.74387636,0,0,,3.00E-12,P46825,Kinesin light chain (KLC),Kinesin light chain (KLC),GO:0005737; GO:0005871; GO:0005874; GO:0003777,cytoplasm; kinesin complex; microtubule; microtubule motor activity,PF13374;,,,,,,,,,KLC_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp31186_c0_seq1,246,56.0976,1.09041112,0,12,,7.00E-22,P59811,Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC),Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC),GO:0016021; GO:0005886; GO:0051205; GO:0015031,integral to membrane; plasma membrane; protein insertion into membrane; protein transport,PF02096;,,,,,,,,,YIDC_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),protein insertion into membrane [GO:0051205]; protein transport [GO:0015031] comp31201_c0_seq1,252,39.6825,0.81091021,5,7,,7.00E-16,Q9CWL2,Zinc finger protein castor homolog 1 (Castor-related protein),Zinc finger protein castor homolog 1 (Castor-related protein),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,CASZ1_MOUSE,Mus musculus (Mouse),"central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]" comp31207_c0_seq1,286,41.6084,0.49426551,8,0,,2.00E-09,A2A863,Integrin beta-4 (CD antigen CD104),Integrin beta-4 (CD antigen CD104),GO:0009925; GO:0005604; GO:0007155; GO:0031252; GO:0048870; GO:0007160; GO:0046847; GO:0030056; GO:0031581; GO:0008305; GO:0007229; GO:0007275; GO:0004872; GO:0009611,basal plasma membrane; basement membrane; cell adhesion; cell leading edge; cell motility; cell-matrix adhesion; filopodium assembly; hemidesmosome; hemidesmosome assembly; integrin complex; integrin-mediated signaling pathway; multicellular organismal development; receptor activity; response to wounding,PF03160;PF00041;PF07965;PF00362;,,,,,,,,,ITB4_MOUSE,Mus musculus (Mouse),amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; digestive tract development [GO:0048565]; filopodium assembly [GO:0046847]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]; trophoblast cell migration [GO:0061450] comp31234_c0_seq1,296,40.5405,0.66000753,1,14,,2.00E-19,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp31238_c0_seq1,334,46.4072,0.39240646,10,0,,5.00E-19,Q8C5V5,WD repeat-containing protein 27,WD repeat-containing protein 27,,,PF00400;,,,,,,,,,WDR27_MOUSE,Mus musculus (Mouse), comp31296_c0_seq1,227,39.6476,1.2692554,2,7,,,,,,,,,8.00E-29,CHOYP_LOC100371059.1.1,,,,,,,,, comp31306_c0_seq1,315,40.6349,0.54123374,7,5,,1.00E-18,Q6DEL1,Putative sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7),Putative sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7),GO:0006865; GO:0016021; GO:0006814,amino acid transport; integral to membrane; sodium ion transport,PF01490;,,,,,,,,,S38A7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),asparagine transport [GO:0006867]; aspartate transport [GO:0015810]; L-alanine transport [GO:0015808]; L-serine transport [GO:0015825]; sodium ion transport [GO:0006814] comp31340_c0_seq1,390,51.5385,0.77441587,3,16,,5.00E-16,Q8MQW8,Protein sprint (SH2 poly-proline-containing Ras-interactor protein),Protein sprint (SH2 poly-proline-containing Ras-interactor protein),GO:0005096; GO:0007298; GO:0005938; GO:0030139; GO:0006897; GO:0005085; GO:0007275; GO:0043547; GO:0007165,GTPase activator activity; border follicle cell migration; cell cortex; endocytic vesicle; endocytosis; guanyl-nucleotide exchange factor activity; multicellular organismal development; positive regulation of GTPase activity; signal transduction,PF00788;PF00017;PF02204;,,,,,,,,,SPRI_DROME,Drosophila melanogaster (Fruit fly),axon extension [GO:0048675]; border follicle cell migration [GO:0007298]; endocytosis [GO:0006897]; regulation of Rab protein signal transduction [GO:0032483]; signal transduction [GO:0007165] comp31387_c0_seq1,222,47.2973,0.48904501,0,9,,3.00E-12,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp31409_c0_seq1,244,37.7049,0.69768614,7,0,,6.00E-15,P0C6F1,"Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)","Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,7.00E-17,CHOYP_DYH2.1.1,,,,,,,DYH2_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp31412_c0_seq1,333,51.0511,0.6486395,6,16,,,,,,,,,3.00E-23,CHOYP_BRAFLDRAFT_75632.1.1,,,,,,,,, comp31421_c0_seq1,236,47.8814,0.68366612,7,0,,5.00E-21,A6QQM4,Zinc finger protein 474,Zinc finger protein 474,GO:0046872,metal ion binding,,7.00E-42,CHOYP_LOC100368109.1.1,,,,,,,ZN474_BOVIN,Bos taurus (Bovine), comp31424_c0_seq1,372,39.5161,0.28087552,13,21,,9.00E-18,Q6TEK3,Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1),Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4),GO:0016021,integral to membrane,PF07884;,,,,,,,,,VKORL_RAT,Rattus norvegicus (Rat),cellular response to oxidative stress [GO:0034599]; peptidyl-glutamic acid carboxylation [GO:0017187]; vitamin K metabolic process [GO:0042373] comp31438_c1_seq1,860,40.4651,0.40111864,24,7,,7.00E-45,A1L1W9,Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10),GO:0016021; GO:0005886; GO:0055085,integral to membrane; plasma membrane; transmembrane transport,PF07690;,,,,,,,,,MOT10_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ion transmembrane transport [GO:0034220] comp31468_c0_seq1,337,50.1484,1.11728492,7,11,,7.00E-33,P26224,"Endoglucanase F (EGF) (EC 3.2.1.4) (Cellulase F) (Endo-1,4-beta-glucanase)","Endoglucanase F (EGF) (EC 3.2.1.4) (Cellulase F) (Endo-1,4-beta-glucanase)",GO:0008810; GO:0030248; GO:0030245,cellulase activity; cellulose binding; cellulose catabolic process,PF00942;PF00404;PF00759;,,,,,,,,,GUNF_CLOTH,Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum),cellulose catabolic process [GO:0030245] comp31475_c0_seq1,213,47.8873,0.58700353,3,7,,1.00E-16,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,1.00E-19,CHOYP_LOC591417.2.2,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp31507_c0_seq1,307,46.9055,0.53514081,17,0,,6.00E-37,A6H8I2,Small G protein signaling modulator 3 homolog (RUN and TBC1 domain-containing protein 3),Small G protein signaling modulator 3 homolog (RUN and TBC1 domain-containing protein 3),GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF02759;PF00018;,1.00E-40,CHOYP_LOC100116018.1.1,,,,,,,SGSM3_XENLA,Xenopus laevis (African clawed frog), comp31509_c0_seq1,273,43.2234,0.78736689,15,0,,1.00E-20,Q01792,Protein krueppel (Fragment),Protein krueppel (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0035282,DNA binding; metal ion binding; nucleus; segmentation,PF00096;,,,,,,,,,KRUP_SCICO,Bradysia coprophila (Dark-winged fungus gnat) (Sciara coprophila),segmentation [GO:0035282] comp3150_c0_seq1,316,37.9747,0.72257318,6,4,,2.00E-06,Q9Y4C8,Probable RNA-binding protein 19 (RNA-binding motif protein 19),Probable RNA-binding protein 19 (RNA-binding motif protein 19),GO:0003723; GO:0005694; GO:0005737; GO:0007275; GO:0005730; GO:0005654; GO:0000166; GO:0040019,RNA binding; chromosome; cytoplasm; multicellular organismal development; nucleolus; nucleoplasm; nucleotide binding; positive regulation of embryonic development,PF00076;,,,,,,,,,RBM19_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019] comp31525_c0_seq1,284,42.2535,0.39983661,12,34,,9.00E-22,Q8BU14,Translocation protein SEC62 (Translocation protein 1) (TP-1),Translocation protein SEC62 (Translocation protein 1) (TP-1),GO:0016235; GO:0005789; GO:0016021; GO:0045111; GO:0016020; GO:0006620; GO:0008565,aggresome; endoplasmic reticulum membrane; integral to membrane; intermediate filament cytoskeleton; membrane; posttranslational protein targeting to membrane; protein transporter activity,PF03839;,,,,,,,,,SEC62_MOUSE,Mus musculus (Mouse),posttranslational protein targeting to membrane [GO:0006620] comp3154_c0_seq1,430,40.6977,0.5631073,9,0,,2.00E-38,P24399,Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2),Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN239_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp31550_c0_seq1,527,44.4023,0.65879136,19,0,,3.00E-07,Q5RBR6,SPRY domain-containing protein 3,SPRY domain-containing protein 3,,,PF00622;,,,,,,,,,SPRY3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp31568_c0_seq1,237,40.9283,0.50596139,12,0,,4.00E-07,Q8NBI5,Solute carrier family 43 member 3 (Protein FOAP-13),Solute carrier family 43 member 3 (Protein FOAP-13),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S43A3_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp31578_c1_seq1,371,42.0485,0.79960898,5,17,,2.00E-07,Q24143,Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1),Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1),GO:0000977; GO:0042632; GO:0004879; GO:0005634; GO:0070873; GO:0042594; GO:0003707; GO:0070328; GO:0008270,RNA polymerase II regulatory region sequence-specific DNA binding; cholesterol homeostasis; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; regulation of glycogen metabolic process; response to starvation; steroid hormone receptor activity; triglyceride homeostasis; zinc ion binding,PF00104;PF00105;,,,,,,,,,HR96_DROME,Drosophila melanogaster (Fruit fly),"cholesterol homeostasis [GO:0042632]; regulation of glucose metabolic process [GO:0010906]; regulation of glycogen metabolic process [GO:0070873]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to starvation [GO:0042594]; steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]" comp31614_c0_seq1,203,61.0837,1.32815723,1,9,,4.00E-41,Q6A8F7,Cytidylate kinase (CK) (EC 2.7.4.25) (Cytidine monophosphate kinase) (CMP kinase),Cytidylate kinase (CK) (EC 2.7.4.25) (Cytidine monophosphate kinase) (CMP kinase),GO:0005524; GO:0004127; GO:0005737; GO:0006220,ATP binding; cytidylate kinase activity; cytoplasm; pyrimidine nucleotide metabolic process,PF02224;,,,,,,,,,KCY_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),pyrimidine nucleotide metabolic process [GO:0006220] comp31643_c0_seq1,279,40.5018,0,4,36,,,,,,,,,2.00E-13,CHOYP_contig_043126,,,,,,,,, comp31660_c0_seq1,228,42.9825,0.47768962,1,7,,2.00E-09,Q6ZTB9,Putative zinc finger protein 833,Putative zinc finger protein 833,GO:0046872; GO:0003676,metal ion binding; nucleic acid binding,PF13912;,,,,,,,,,ZN833_HUMAN,Homo sapiens (Human), comp31665_c0_seq1,415,46.747,0.53333643,20,1,,2.00E-36,Q9QYP1,Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),GO:0016055; GO:0005509; GO:0030154; GO:0009953; GO:0042733; GO:0006897; GO:0001942; GO:0016021; GO:0001822; GO:0090090; GO:0030279; GO:0042475; GO:0005886; GO:0009954; GO:0043113; GO:0001932; GO:0051124,Wnt receptor signaling pathway; calcium ion binding; cell differentiation; dorsal/ventral pattern formation; embryonic digit morphogenesis; endocytosis; hair follicle development; integral to membrane; kidney development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of ossification; odontogenesis of dentin-containing tooth; plasma membrane; proximal/distal pattern formation; receptor clustering; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF12662;PF00057;PF00058;,,,,,,,,,LRP4_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] comp31669_c0_seq1,363,38.5675,0.66871297,1,15,,3.00E-11,P58365,Cadherin-23 (Otocadherin),Cadherin-23 (Otocadherin),GO:0005509; GO:0050910; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; detection of mechanical stimulus involved in sensory perception of sound; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;,,,,,,,,,CAD23_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp31676_c0_seq1,249,38.1526,0.34949306,10,0,,2.00E-17,Q91437,CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],GO:0044205; GO:0006207; GO:0005524; GO:0016597; GO:0004070; GO:0070409; GO:0004088; GO:0005737; GO:0004151; GO:0006543; GO:0046872,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; ATP binding; amino acid binding; aspartate carbamoyltransferase activity; carbamoyl phosphate biosynthetic process; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; cytoplasm; dihydroorotase activity; glutamine catabolic process; metal ion binding,PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;,,,,,,,,,PYR1_SQUAC,Squalus acanthias (Spiny dogfish),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541] comp31692_c0_seq1,229,45.8515,0.77645892,0,12,,5.00E-17,P86982,Insoluble matrix shell protein 1 (IMSP1) (Fragment),Insoluble matrix shell protein 1 (IMSP1) (Fragment),GO:0005576,extracellular region,,,,,,,,,,IMSP1_VENPH,Ruditapes philippinarum (Japanese littleneck clam) (Venerupis philippinarum), comp31721_c0_seq1,202,46.0396,0.37909426,5,6,,5.00E-27,Q91XQ0,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0031514,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; motile cilium,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-36,CHOYP_DNAH5.1.2,,,,,,,DYH8_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp31731_c0_seq1,268,44.403,0.53283141,10,0,,4.00E-49,P23640,Ras-related protein Rab-27A (Rab-27) (GTP-binding protein Ram) (Ram p25),Ras-related protein Rab-27A (Rab-27) (GTP-binding protein Ram) (Ram p25),GO:0019003; GO:0005525; GO:0003924; GO:0005794; GO:0016324; GO:0007596; GO:0043316; GO:0030425; GO:0070382; GO:0006887; GO:0005764; GO:0030318; GO:0042470; GO:0032402; GO:0032585; GO:0071985; GO:0043320; GO:0001750; GO:0045921; GO:0006605; GO:0030667; GO:0007264,GDP binding; GTP binding; GTPase activity; Golgi apparatus; apical plasma membrane; blood coagulation; cytotoxic T cell degranulation; dendrite; exocytic vesicle; exocytosis; lysosome; melanocyte differentiation; melanosome; melanosome transport; multivesicular body membrane; multivesicular body sorting pathway; natural killer cell degranulation; photoreceptor outer segment; positive regulation of exocytosis; protein targeting; secretory granule membrane; small GTPase mediated signal transduction,PF00071;,2.00E-36,CHOYP_RB27A.1.1,,,,,,,RB27A_RAT,Rattus norvegicus (Rat),antigen processing and presentation [GO:0019882]; blood coagulation [GO:0007596]; complement-dependent cytotoxicity [GO:0097278]; cytotoxic T cell degranulation [GO:0043316]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; multivesicular body organization [GO:0036257]; multivesicular body sorting pathway [GO:0071985]; natural killer cell degranulation [GO:0043320]; positive regulation of constitutive secretory pathway [GO:1903435]; positive regulation of exocytosis [GO:0045921]; positive regulation of gene expression [GO:0010628]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of regulated secretory pathway [GO:1903307]; protein targeting [GO:0006605]; small GTPase mediated signal transduction [GO:0007264] comp31755_c1_seq1,224,63.8393,1.01234412,0,11,,9.00E-39,Q6A6H1,NADH-quinone oxidoreductase subunit N (EC 1.6.99.5) (NADH dehydrogenase I subunit N) (NDH-1 subunit N),NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N),GO:0042773; GO:0008137; GO:0016021; GO:0005886; GO:0048038; GO:0006810,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; integral to membrane; plasma membrane; quinone binding; transport,PF00361;,,,,,,,,,NUON_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),ATP synthesis coupled electron transport [GO:0042773]; transport [GO:0006810] comp31767_c0_seq1,294,42.517,0.91949116,1,6,,2.00E-14,Q61147,Ceruloplasmin (EC 1.16.3.1) (Ferroxidase),Ceruloplasmin (EC 1.16.3.1) (Ferroxidase),GO:0006879; GO:0005507; GO:0006825; GO:0005615; GO:0004322,cellular iron ion homeostasis; copper ion binding; copper ion transport; extracellular space; ferroxidase activity,PF00394;PF07731;PF07732;,,,,,,,,,CERU_MOUSE,Mus musculus (Mouse),cellular iron ion homeostasis [GO:0006879]; copper ion transport [GO:0006825] comp31797_c0_seq1,280,35.3571,0.3545041,2,10,,9.00E-12,Q8TEQ8,GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O),GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O),GO:0006501; GO:0005789; GO:0016021; GO:0016254; GO:0016740,C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane; transferase activity,PF01663;,,,,,,,,,PIGO_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506] comp31800_c0_seq1,459,45.5338,1.35810168,0,0,,,,,,,,,,,2.00E-12,ruditapes_c7550,,,,,,, comp31817_c0_seq1,275,45.0909,0.4312557,9,6,,8.00E-41,P25391,Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),GO:0007411; GO:0060445; GO:0007155; GO:0007166; GO:0005911; GO:0060441; GO:0045198; GO:0030198; GO:0005201; GO:0005615; GO:0043208; GO:0005606; GO:0005608; GO:0002011; GO:0030155; GO:0030334; GO:0045995; GO:0061304,axon guidance; branching involved in salivary gland morphogenesis; cell adhesion; cell surface receptor signaling pathway; cell-cell junction; epithelial tube branching involved in lung morphogenesis; establishment of epithelial cell apical/basal polarity; extracellular matrix organization; extracellular matrix structural constituent; extracellular space; glycosphingolipid binding; laminin-1 complex; laminin-3 complex; morphogenesis of an epithelial sheet; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; retinal blood vessel morphogenesis,PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;,3.00E-15,CHOYP_LAMA2.1.1,,,,,,,LAMA1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995] comp31827_c0_seq1,256,46.4844,0.50819984,7,5,,4.00E-15,Q8BHT7,Retrograde Golgi transport protein RGP1 homolog,RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog),,,PF08737;,,,,,,,,,RGP1_MOUSE,Mus musculus (Mouse),"negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]" comp31843_c0_seq1,245,47.7551,0.88596914,2,0,,3.00E-06,Q98ST7,DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_CHICK,Gallus gallus (Chicken), comp31869_c0_seq1,272,52.9412,0.21568532,10,0,,7.00E-34,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,4.00E-40,CHOYP_MRP4.1.3,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp31896_c0_seq1,295,45.7627,0.32628241,6,10,,2.00E-20,Q9W1V1,Protein arginine N-methyltransferase 7 (Dart7) (EC 2.1.1.-),Protein arginine N-methyltransferase 7 (Dart7) (EC 2.1.1.-),GO:0005737; GO:0019919; GO:0035243,"cytoplasm; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; protein-arginine omega-N symmetric methyltransferase activity",,,,,,,,,,ANM7_DROME,Drosophila melanogaster (Fruit fly),"peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of transcription, DNA-templated [GO:0006355]" comp31900_c0_seq1,230,68.2609,0.97787586,0,11,,3.00E-22,B1XT71,4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8),4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8),GO:0008839; GO:0051287; GO:0070402; GO:0005737; GO:0019877; GO:0009089; GO:0016726,"4-hydroxy-tetrahydrodipicolinate reductase; NAD binding; NADPH binding; cytoplasm; diaminopimelate biosynthetic process; lysine biosynthetic process via diaminopimelate; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor",PF05173;PF01113;,,,,,,,,,DAPB_POLNS,Polynucleobacter necessarius subsp. necessarius (strain STIR1),diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089] comp3191_c0_seq1,550,34.3636,0.86383264,8,5,,6.00E-20,A5D794,GTPase-activating protein and VPS9 domain-containing protein 1,GTPase-activating protein and VPS9 domain-containing protein 1,GO:0032794; GO:0005096; GO:0005829; GO:0006897; GO:0005768; GO:0005085; GO:0016020; GO:0043547; GO:0051223; GO:0051056; GO:0007165,GTPase activating protein binding; GTPase activator activity; cytosol; endocytosis; endosome; guanyl-nucleotide exchange factor activity; membrane; positive regulation of GTPase activity; regulation of protein transport; regulation of small GTPase mediated signal transduction; signal transduction,PF00616;PF02204;,8.00E-21,CHOYP_LOC100645706.1.1,,,,,,,GAPD1_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165] comp31997_c0_seq1,416,42.7885,0.57917001,15,28,,3.00E-15,O35507,Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1),Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1),GO:0008144; GO:0070166; GO:0008544; GO:0006631; GO:0004879; GO:0008289; GO:0032099; GO:0010887; GO:0010871; GO:0010891; GO:0000122; GO:0005634; GO:0046321; GO:0045893; GO:0072366; GO:0072363; GO:0072369; GO:0043565; GO:0003707; GO:0042060; GO:0008270,"drug binding; enamel mineralization; epidermis development; fatty acid metabolic process; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; lipid binding; negative regulation of appetite; negative regulation of cholesterol storage; negative regulation of receptor biosynthetic process; negative regulation of sequestering of triglyceride; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of fatty acid oxidation; positive regulation of transcription, DNA-dependent; regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter; regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; steroid hormone receptor activity; wound healing; zinc ion binding",PF00104;PF00105;,1.00E-36,CHOYP_DGRI_GH14972.1.1,,,,,,,PPARA_CAVPO,Cavia porcellus (Guinea pig),"circadian regulation of gene expression [GO:0032922]; enamel mineralization [GO:0070166]; epidermis development [GO:0008544]; fatty acid metabolic process [GO:0006631]; negative regulation of appetite [GO:0032099]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902894]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072366]; regulation of circadian rhythm [GO:0042752]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; wound healing [GO:0042060]" comp32013_c1_seq1,229,39.3013,0.23663003,6,0,,,,,,,,,1.00E-14,CHOYP_LOC101171601.1.1,,,,,,,,, comp32067_c0_seq1,220,45.4545,0.44846706,10,0,,1.00E-09,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp32101_c0_seq1,333,46.2462,0.78920543,4,21,,9.00E-06,Q8QFX1,RIMS-binding protein 2 (RIM-BP2),RIMS-binding protein 2 (RIM-BP2),GO:0030054; GO:0010923; GO:0005886; GO:0045202,cell junction; negative regulation of phosphatase activity; plasma membrane; synapse,PF07653;PF14604;,,,,,,,,,RIMB2_CHICK,Gallus gallus (Chicken),negative regulation of phosphatase activity [GO:0010923] comp32150_c0_seq1,212,41.9811,0.6553992,0,23,,1.00E-23,Q4R4Y9,Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2),Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2),GO:0005524; GO:0008026; GO:0003743,ATP binding; ATP-dependent helicase activity; translation initiation factor activity,PF00270;PF00271;,2.00E-28,CHOYP_EF1A.3.4,,,,,,,IF4A2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),regulation of translational initiation [GO:0006446] comp32151_c0_seq1,265,58.8679,1.00975196,0,17,,8.00E-21,P26905,Dipeptide transport ATP-binding protein DppD,Dipeptide transport ATP-binding protein DppD,GO:0005524; GO:0006200; GO:0016887; GO:0015197; GO:0005886; GO:0015031; GO:0030435,ATP binding; ATP catabolic process; ATPase activity; peptide transporter activity; plasma membrane; protein transport; sporulation resulting in formation of a cellular spore,PF00005;PF08352;,,,,,,,,,DPPD_BACSU,Bacillus subtilis (strain 168),peptide transport [GO:0015833]; protein transport [GO:0015031]; sporulation resulting in formation of a cellular spore [GO:0030435] comp32168_c0_seq1,263,46.3878,0.93848773,2,24,,2.00E-11,Q9UT25,Uncharacterized N-acetyltransferase C9.02c (EC 2.3.1.-),Uncharacterized N-acetyltransferase C9.02c (EC 2.3.1.-),GO:0004059; GO:0004145,aralkylamine N-acetyltransferase activity; diamine N-acetyltransferase activity,PF13673;,,,,,,,,,YFY2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast), comp32169_c0_seq1,222,48.1982,0.23842251,9,2,,3.00E-24,A0JNG7,Protein FAM160B1,Protein FAM160B1,,,PF10257;,4.00E-19,CHOYP_F16B1.1.1,,,,,,,F16B1_BOVIN,Bos taurus (Bovine), comp32183_c0_seq1,387,39.7933,0.93898639,13,7,,2.00E-09,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp32224_c0_seq1,337,44.8071,0.29711935,3,7,,2.00E-18,Q6DCL5,E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1),E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1),GO:0032580; GO:0000139; GO:0007030; GO:0017137; GO:0007049; GO:0005783; GO:0061025; GO:0070936; GO:0042787; GO:0030334; GO:0004842,Golgi cisterna membrane; Golgi membrane; Golgi organization; Rab GTPase binding; cell cycle; endoplasmic reticulum; membrane fusion; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of cell migration; ubiquitin-protein ligase activity,PF12796;PF00632;,,,,,,,,,HACE1_XENLA,Xenopus laevis (African clawed frog),cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell migration [GO:0030334] comp32237_c0_seq1,284,44.7183,0.87693395,5,7,,2.00E-40,Q704E8,"ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)","ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)",GO:0005524; GO:0042626; GO:0006879; GO:0016021; GO:0005743,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; cellular iron ion homeostasis; integral to membrane; mitochondrial inner membrane",PF00664;PF00005;,,,,,,,,,ABCB7_RAT,Rattus norvegicus (Rat),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp32238_c0_seq1,425,37.4118,0.28687028,8,13,,3.00E-07,Q8K3Y6,Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger antiviral protein) (ZAP) (rZAP),Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger antiviral protein) (ZAP) (rZAP),GO:0003723; GO:0005737; GO:0051607; GO:0045087; GO:0046872; GO:0045071; GO:0005634; GO:0061014; GO:0050691; GO:0009615,RNA binding; cytoplasm; defense response to virus; innate immune response; metal ion binding; negative regulation of viral genome replication; nucleus; positive regulation of mRNA catabolic process; regulation of defense response to virus by host; response to virus,PF02825;,,,,,,,,,ZCCHV_RAT,Rattus norvegicus (Rat),defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615] comp32244_c0_seq1,306,44.7712,0.52479193,3,9,,2.00E-12,Q24145,Tyrosine-protein kinase shark (EC 2.7.10.2),Tyrosine-protein kinase shark (EC 2.7.10.2),GO:0005524; GO:0007254; GO:0043277; GO:0005938; GO:0046843; GO:0007394; GO:0045199; GO:0048812; GO:0004715,"ATP binding; JNK cascade; apoptotic cell clearance; cell cortex; dorsal appendage formation; dorsal closure, elongation of leading edge cells; maintenance of epithelial cell apical/basal polarity; neuron projection morphogenesis; non-membrane spanning protein tyrosine kinase activity",PF12796;PF07714;PF00017;,,,,,,,,,SHARK_DROME,Drosophila melanogaster (Fruit fly),"apoptotic cell clearance [GO:0043277]; cell migration [GO:0016477]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, elongation of leading edge cells [GO:0007394]; eggshell chorion assembly [GO:0007306]; innate immune response [GO:0045087]; JNK cascade [GO:0007254]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neuron projection morphogenesis [GO:0048812]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; regulation of glucose metabolic process [GO:0010906]; sleep [GO:0030431]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" comp32247_c0_seq1,283,42.0495,0.24081703,5,12,,1.00E-34,A1L258,"D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)","D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)",GO:0008762; GO:0050660; GO:0005739,UDP-N-acetylmuramate dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrion,PF02913;PF01565;,,,,,,,,,D2HDH_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp32247_c1_seq1,246,45.5285,0.4000714,1,7,,3.00E-32,O23240,"D-2-hydroxyglutarate dehydrogenase, mitochondrial (AtD-2HGDH) (EC 1.1.99.-)","D-2-hydroxyglutarate dehydrogenase, mitochondrial (AtD-2HGDH) (EC 1.1.99.39)",GO:0051990; GO:0008762; GO:0050660; GO:0005739,(R)-2-hydroxyglutarate dehydrogenase activity; UDP-N-acetylmuramate dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrion,PF02913;PF01565;,2.00E-29,CHOYP_LOC100367659.1.1,,,,,,,D2HDH_ARATH,Arabidopsis thaliana (Mouse-ear cress),nitrogen compound metabolic process [GO:0006807]; photorespiration [GO:0009853] comp3224_c0_seq1,257,51.3619,0.89855087,6,1,,5.00E-18,Q9H324,A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAM-TS 10) (ADAM-TS10) (ADAMTS-10) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAM-TS 10) (ADAM-TS10) (ADAMTS-10) (EC 3.4.24.-),GO:0004222; GO:0001527; GO:0006508; GO:0008270,metalloendopeptidase activity; microfibril; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS10_HUMAN,Homo sapiens (Human), comp32257_c0_seq1,287,39.3728,0.83560009,0,20,,3.00E-06,Q9MZT2,Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1),Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1),GO:0016021; GO:0001882; GO:0005415; GO:0005886,integral to membrane; nucleoside binding; nucleoside:sodium symporter activity; plasma membrane,PF07670;PF07662;PF01773;,,,,,,,,,S28A1_RABIT,Oryctolagus cuniculus (Rabbit), comp32274_c0_seq1,330,43.3333,0.72242727,5,10,,2.00E-14,Q9Y345,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0015375; GO:0016021; GO:0005328; GO:0005886; GO:0007268,glycine:sodium symporter activity; integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane; synaptic transmission,PF00209;,,,,,,,,,SC6A5_HUMAN,Homo sapiens (Human),"chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp32280_c0_seq1,208,40.8654,0.58056897,1,9,,8.00E-12,A4IF63,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_BOVIN,Bos taurus (Bovine),regulation of neuron apoptotic process [GO:0043523] comp32311_c0_seq1,255,43.1373,0.62201581,1,17,,5.00E-08,Q54IT3,Probable flavin-containing monoamine oxidase A (EC 1.4.3.4),Probable flavin-containing monoamine oxidase A (EC 1.4.3.4),GO:0016491,oxidoreductase activity,PF01593;,1.00E-13,CHOYP_SMP_012720.2.2,,,,,,,AOFA_DICDI,Dictyostelium discoideum (Slime mold), comp32331_c0_seq1,214,64.0187,0.83227624,1,5,,2.00E-32,Q9APC2,Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) (Fragment),Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) (Fragment),GO:0051539; GO:0046872; GO:0009399; GO:0016491,"4 iron, 4 sulfur cluster binding; metal ion binding; nitrogen fixation; oxidoreductase activity",PF17147;PF01855;,,,,,,,,,NIFJ_ANASO,Nostoc sp. (strain ATCC 29151 / PCC 7119) (Anabaena sp.),nitrogen fixation [GO:0009399] comp32350_c0_seq1,346,54.0462,0.67525747,3,5,,9.00E-16,P32399,Uncharacterized protein YhgE (ORFB),Uncharacterized protein YhgE (ORFB),GO:0016021; GO:0005886,integral to membrane; plasma membrane,,,,,,,,,,YHGE_BACSU,Bacillus subtilis (strain 168),transmembrane transport [GO:0055085] comp32355_c1_seq1,436,38.5321,0.5757606,7,13,,7.00E-11,O08648,Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),GO:0005524; GO:0004709; GO:0000165; GO:0000186; GO:0060718; GO:0005737; GO:0048263; GO:0019100; GO:0046872; GO:0048471; GO:0001890; GO:0043507; GO:0004672; GO:0010468,ATP binding; MAP kinase kinase kinase activity; MAPK cascade; activation of MAPKK activity; chorionic trophoblast cell differentiation; cytoplasm; determination of dorsal identity; male germ-line sex determination; metal ion binding; perinuclear region of cytoplasm; placenta development; positive regulation of JUN kinase activity; protein kinase activity; regulation of gene expression,PF00069;,,,,,,,,,M3K4_MOUSE,Mus musculus (Mouse),activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; determination of dorsal identity [GO:0048263]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] comp32372_c0_seq1,218,62.844,1.31873743,0,10,,4.00E-42,Q6A9J8,UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C),UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C),GO:0003677; GO:0009432; GO:0005737; GO:0009381; GO:0009380; GO:0006289,DNA binding; SOS response; cytoplasm; excinuclease ABC activity; excinuclease repair complex; nucleotide-excision repair,PF01541;PF02151;PF08459;,,,,,,,,,UVRC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432] comp32375_c0_seq1,243,40.7407,0.49919012,3,13,,4.00E-15,Q96MR6,WD repeat-containing protein 65,Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65),,,PF00400;,6.00E-18,CHOYP_LOC100371909.1.1,,,,,,,WDR65_HUMAN,Homo sapiens (Human), comp32405_c0_seq1,238,40.3361,0.62675932,5,4,,6.00E-10,Q642A2,Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein),Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein),GO:0000139; GO:0004945; GO:0005938; GO:0030659; GO:0005789; GO:0016021; GO:0005886; GO:0008217; GO:0001666,Golgi membrane; angiotensin type II receptor activity; cell cortex; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; integral to membrane; plasma membrane; regulation of blood pressure; response to hypoxia,PF06396;,,,,,,,,,ATRAP_RAT,Rattus norvegicus (Rat),regulation of blood pressure [GO:0008217]; response to hypoxia [GO:0001666] comp32434_c0_seq1,343,37.3178,0.17135887,20,0,,1.00E-13,Q6IE36,Ovostatin homolog 2,Ovostatin homolog 2,GO:0005615; GO:0010951; GO:0004867,extracellular space; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,OVOS2_HUMAN,Homo sapiens (Human), comp32450_c0_seq1,241,42.7386,0.46148773,11,0,,5.00E-30,P23470,Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48),GO:0005887; GO:0007169; GO:0005001,integral to plasma membrane; transmembrane receptor protein tyrosine kinase signaling pathway; transmembrane receptor protein tyrosine phosphatase activity,PF00194;PF00041;PF00102;,1.00E-13,CHOYP_LOC660278.2.2,,,,,,,PTPRG_HUMAN,Homo sapiens (Human),negative regulation of epithelial cell migration [GO:0010633]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp32451_c1_seq1,300,47.3333,0.48735615,8,0,,3.00E-10,A1ZAJ2,Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104),Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104),GO:0005524; GO:0048490; GO:0007411; GO:0005737; GO:0005871; GO:0008345; GO:0005874; GO:0005875; GO:0003777; GO:0007528; GO:0005543; GO:0016188; GO:0047496,ATP binding; anterograde synaptic vesicle transport; axon guidance; cytoplasm; kinesin complex; larval locomotory behavior; microtubule; microtubule associated complex; microtubule motor activity; neuromuscular junction development; phospholipid binding; synaptic vesicle maturation; vesicle transport along microtubule,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,,,,,,,,,KIF1A_DROME,Drosophila melanogaster (Fruit fly),anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; axo-dendritic transport [GO:0008088]; axon guidance [GO:0007411]; filopodium assembly [GO:0046847]; larval locomotory behavior [GO:0008345]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuromuscular junction development [GO:0007528]; positive regulation of insulin secretion [GO:0032024]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotion [GO:0040012]; regulation of synapse assembly [GO:0051963]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192]; vesicle transport along microtubule [GO:0047496] comp32484_c0_seq1,421,39.1924,1.01932942,10,4,,6.00E-15,Q32LN0,ETS homologous factor (ETS domain-containing transcription factor),ETS homologous factor (ETS domain-containing transcription factor),GO:0030855; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"epithelial cell differentiation; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,5.00E-16,CHOYP_LOC100878929.1.1,1.00E-34,ruditapes_c25355,,,,,EHF_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp3249_c0_seq1,209,45.933,1.25060124,3,0,,2.00E-35,Q8JZP9,GAS2-like protein 1 (Growth arrest-specific protein 2-like 1),GAS2-like protein 1 (Growth arrest-specific protein 2-like 1),GO:0007050; GO:0009267; GO:0097067; GO:0005737; GO:0008093; GO:0005856; GO:0008017; GO:0001578; GO:0030308; GO:0045647; GO:0010629; GO:0007026; GO:0051726; GO:0046966,cell cycle arrest; cellular response to starvation; cellular response to thyroid hormone stimulus; cytoplasm; cytoskeletal adaptor activity; cytoskeleton; microtubule binding; microtubule bundle formation; negative regulation of cell growth; negative regulation of erythrocyte differentiation; negative regulation of gene expression; negative regulation of microtubule depolymerization; regulation of cell cycle; thyroid hormone receptor binding,PF00307;PF02187;,7.00E-35,CHOYP_PHUM_PHUM215460.1.1,,,,,,,GA2L1_MOUSE,Mus musculus (Mouse),cell cycle arrest [GO:0007050]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of cell cycle [GO:0051726] comp32503_c0_seq1,819,45.6654,0.56804818,12,62,,3.00E-72,Q68CP4,Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76),GO:0005975; GO:0006027; GO:0015019; GO:0016021; GO:0005765; GO:0007041; GO:0051259; GO:0044281; GO:0016746,"carbohydrate metabolic process; glycosaminoglycan catabolic process; heparan-alpha-glucosaminide N-acetyltransferase activity; integral to membrane; lysosomal membrane; lysosomal transport; protein oligomerization; small molecule metabolic process; transferase activity, transferring acyl groups",PF07786;,2.00E-63,CHOYP_HGSNAT.1.2,,,,,,,HGNAT_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259] comp32515_c0_seq1,238,47.8992,0.3035938,1,8,,2.00E-08,Q8WXG9,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0009986; GO:0016337; GO:0005737; GO:0050910; GO:0060122; GO:0016021; GO:0048496; GO:0007399; GO:0007218; GO:0045494; GO:0005886; GO:0050953; GO:0007605; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell surface; cell-cell adhesion; cytoplasm; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor stereocilium organization; integral to membrane; maintenance of organ identity; nervous system development; neuropeptide signaling pathway; photoreceptor cell maintenance; plasma membrane; sensory perception of light stimulus; sensory perception of sound; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp32522_c0_seq1,340,44.4118,0.53899307,4,15,,2.00E-44,O15438,Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3),Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3),GO:0005524; GO:0042626; GO:0015721; GO:0008206; GO:0005887; GO:0008514,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; bile acid and bile salt transport; bile acid metabolic process; integral to plasma membrane; organic anion transmembrane transporter activity",PF00664;PF00005;,3.00E-42,CHOYP_MRP1.5.10,,,,,,,MRP3_HUMAN,Homo sapiens (Human),bile acid and bile salt transport [GO:0015721]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp32527_c0_seq1,412,39.0777,0.84899298,9,5,,1.00E-12,Q08AN1,Zinc finger protein 616,Zinc finger protein 616,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN616_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp32529_c0_seq1,367,61.0354,1.08546724,1,21,,8.00E-22,O07399,3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase),GO:0004316; GO:0050661; GO:0030497,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NADP binding; fatty acid elongation,,,,,,,,,,FABG_MYCAV,Mycobacterium avium,fatty acid elongation [GO:0030497] comp3252_c0_seq1,486,47.1193,0.45030242,15,1,,4.00E-43,Q8TE57,A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,,,,,,,,,ATS16_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] comp32546_c0_seq1,278,41.0072,0.43417929,11,0,,3.00E-12,Q9ESQ5,Transient receptor potential cation channel subfamily M member 4 (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (MLS2s) (Melastatin-like 2),Transient receptor potential cation channel subfamily M member 4 (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (MLS2s) (Melastatin-like 2),GO:0005524; GO:0005794; GO:0005227; GO:0005262; GO:0002407; GO:0005783; GO:0016021; GO:0005886; GO:0090263; GO:0008284; GO:0016925; GO:0002724,ATP binding; Golgi apparatus; calcium activated cation channel activity; calcium channel activity; dendritic cell chemotaxis; endoplasmic reticulum; integral to membrane; plasma membrane; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell proliferation; protein sumoylation; regulation of T cell cytokine production,PF00520;,,,,,,,,,TRPM4_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; cardiac conduction [GO:0061337]; dendritic cell chemotaxis [GO:0002407]; negative regulation of bone mineralization [GO:0030502]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of atrial cardiac muscle cell action potential [GO:1903949]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of heart rate [GO:0010460]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of regulation of vascular smooth muscle cell membrane depolarization [GO:1904199]; positive regulation of vasoconstriction [GO:0045907]; protein sumoylation [GO:0016925]; regulation of T cell cytokine production [GO:0002724]; vasoconstriction [GO:0042310] comp32663_c0_seq1,265,72.8302,1.14262795,0,11,,9.00E-15,P43899,Oxygen-independent coproporphyrinogen-III oxidase-like protein HI_0463 (EC 1.3.99.-),Oxygen-independent coproporphyrinogen-III oxidase-like protein HI_0463 (EC 1.3.99.-),GO:0051539; GO:0004109; GO:0005737; GO:0046872; GO:0006779,"4 iron, 4 sulfur cluster binding; coproporphyrinogen oxidase activity; cytoplasm; metal ion binding; porphyrin-containing compound biosynthetic process",PF06969;PF04055;,,,,,,,,,Y463_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782] comp32687_c0_seq1,406,38.67,0.47642429,6,9,,3.00E-80,Q8N9R8,Protein SCAI (Suppressor of cancer cell invasion protein),Protein SCAI (Suppressor of cancer cell invasion protein),GO:0005737; GO:0016021; GO:0035024; GO:0030336; GO:0005634; GO:0006355; GO:0003714; GO:0006351,"cytoplasm; integral to membrane; negative regulation of Rho protein signal transduction; negative regulation of cell migration; nucleus; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF12070;,1.00E-98,CHOYP_ISCW_ISCW022658.2.2,,,,,,,SCAI_HUMAN,Homo sapiens (Human),"negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp32689_c0_seq1,475,48.4211,0.57588157,6,49,,2.00E-29,Q58DL5,Breast cancer anti-estrogen resistance protein 3,Breast cancer anti-estrogen resistance protein 3,GO:0005085; GO:0005622; GO:0007264,guanyl-nucleotide exchange factor activity; intracellular; small GTPase mediated signal transduction,PF00617;PF00017;,,,,,,,,,BCAR3_BOVIN,Bos taurus (Bovine),small GTPase mediated signal transduction [GO:0007264] comp32713_c0_seq1,398,42.4623,1.01384039,1,60,,9.00E-07,Q9UKN7,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,9.00E-31,CHOYP_MYO15.1.1,,,,,,,MYO15_HUMAN,Homo sapiens (Human),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp32718_c0_seq1,486,43.0041,0.23485825,11,10,,1.00E-48,Q8N0W3,L-fucose kinase (Fucokinase) (EC 2.7.1.52),L-fucose kinase (Fucokinase) (EC 2.7.1.52),GO:0005524; GO:0005737; GO:0050201,ATP binding; cytoplasm; fucokinase activity,PF07959;PF08544;PF00288;,6.00E-28,CHOYP_FUK.1.1,,,,,,,FUK_HUMAN,Homo sapiens (Human), comp32725_c0_seq1,520,38.0769,0.64024814,7,44,,1.00E-11,Q9BRZ2,E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (RING finger protein 109) (Tripartite motif-containing protein 56),E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (RING finger protein 109) (Tripartite motif-containing protein 56),GO:0005829; GO:0051607; GO:0032608; GO:0032481; GO:0070534; GO:0034340; GO:0004842; GO:0008270,cytosol; defense response to virus; interferon-beta production; positive regulation of type I interferon production; protein K63-linked ubiquitination; response to type I interferon; ubiquitin-protein ligase activity; zinc ion binding,PF00643;PF13445;,,,,,,,,,TRI56_HUMAN,Homo sapiens (Human),defense response to virus [GO:0051607]; interferon-beta production [GO:0032608]; protein K63-linked ubiquitination [GO:0070534]; regulation of type I interferon production [GO:0032479]; response to type I interferon [GO:0034340] comp32731_c0_seq1,250,48,1.11588337,3,0,,5.00E-22,Q9UA35,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT),GO:0016021; GO:0005415,integral to membrane; nucleoside:sodium symporter activity,PF07670;PF07662;PF01773;,,,,,,,,,S28A3_EPTST,Eptatretus stoutii (Pacific hagfish), comp32758_c0_seq1,281,61.5658,1.01244033,0,10,,6.00E-14,Q9MUT3,Magnesium-chelatase subunit ChlI (Mg-chelatase subunit I-1) (EC 6.6.1.1) (Mg-protoporphyrin IX chelatase subunit ChlI),Magnesium-chelatase subunit ChlI (Mg-chelatase subunit I-1) (EC 6.6.1.1) (Mg-protoporphyrin IX chelatase subunit ChlI),GO:0005524; GO:0015995; GO:0009507; GO:0016851; GO:0017111; GO:0015979,ATP binding; chlorophyll biosynthetic process; chloroplast; magnesium chelatase activity; nucleoside-triphosphatase activity; photosynthesis,PF01078;,,,,,,,,,CHLI_MESVI,Mesostigma viride (Green alga),chlorophyll biosynthetic process [GO:0015995]; photosynthesis [GO:0015979] comp32765_c0_seq1,447,41.6107,0.69958308,14,7,,2.00E-17,Q5TZE1,BTB/POZ domain-containing protein 6-B,BTB/POZ domain-containing protein 6-B,GO:0030154; GO:0000932; GO:0007399,cell differentiation; cytoplasmic mRNA processing body; nervous system development,PF07707;PF00651;PF08005;,,,,,,,,,BTB6B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell differentiation [GO:0030154]; nervous system development [GO:0007399] comp3278_c0_seq1,351,40.1709,0.507,6,1,,,,,,,,,8.00E-12,CHOYP_F16B1.1.1,,,,,,,,, comp32828_c0_seq1,450,49.5556,0.95009382,14,2,,2.00E-32,Q6P0Q8,Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1),Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0000287; GO:0015630; GO:0005886; GO:0006468; GO:0004674; GO:0045075; GO:0048515,ATP binding; cytoplasm; magnesium ion binding; microtubule cytoskeleton; plasma membrane; protein phosphorylation; protein serine/threonine kinase activity; regulation of interleukin-12 biosynthetic process; spermatid differentiation,PF08926;PF00595;PF00069;,8.00E-20,CHOYP_MAST4.1.1,,,,,,,MAST2_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of interleukin-12 biosynthetic process [GO:0045075]; spermatid differentiation [GO:0048515] comp32845_c0_seq1,279,49.4624,0.61337042,7,8,,2.00E-08,Q6NYM1,Kelch-like protein 21,Kelch-like protein 21,GO:0031463; GO:0051301; GO:0035853; GO:0005737; GO:0007067; GO:0005827; GO:0016567; GO:0032465,Cul3-RING ubiquitin ligase complex; cell division; chromosome passenger complex localization to spindle midzone; cytoplasm; mitosis; polar microtubule; protein ubiquitination; regulation of cytokinesis,PF07707;PF00651;PF01344;,,,,,,,,,KLH21_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; chromosome passenger complex localization to spindle midzone [GO:0035853]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cytokinesis [GO:0032465] comp3284_c0_seq1,359,46.2396,0.36601591,12,0,,7.00E-08,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,8.00E-12,CHOYP_NEMVEDRAFT_V1G198667.1.15,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp32874_c0_seq1,203,44.335,0.20806216,2,5,,3.00E-23,Q5XF89,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0019829; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; cation-transporting ATPase activity; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,7.00E-29,CHOYP_LOC660831.1.1,,,,,,,AT133_MOUSE,Mus musculus (Mouse),cellular calcium ion homeostasis [GO:0006874] comp32901_c0_seq1,236,43.6441,0.63907157,7,0,,6.00E-09,Q07E02,Caveolin-1,Caveolin-1,GO:0000139; GO:0031295; GO:0005901; GO:0005768,Golgi membrane; T cell costimulation; caveola; endosome,PF01146;,,,,,,,,,CAV1_ORNAN,Ornithorhynchus anatinus (Duckbill platypus),caveola assembly [GO:0070836]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; receptor internalization [GO:0031623]; T cell costimulation [GO:0031295] comp32932_c0_seq1,283,38.5159,0.38639938,12,2,,5.00E-19,Q9H2M9,Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit),GO:0005096; GO:0005737; GO:0006886; GO:0005886; GO:0046982,GTPase activator activity; cytoplasm; intracellular protein transport; plasma membrane; protein heterodimerization activity,PF14656;PF14655;,7.00E-12,CHOYP_RBGPR.1.1,,,,,,,RBGPR_HUMAN,Homo sapiens (Human),establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] comp32973_c0_seq1,213,44.1315,0.48637436,6,0,,6.00E-18,P54802,Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],GO:0004561; GO:0005975; GO:0021680; GO:0006027; GO:0060119; GO:0045475; GO:0043202; GO:0007040; GO:0042474; GO:0007399; GO:0046548; GO:0044281,alpha-N-acetylglucosaminidase activity; carbohydrate metabolic process; cerebellar Purkinje cell layer development; glycosaminoglycan catabolic process; inner ear receptor cell development; locomotor rhythm; lysosomal lumen; lysosome organization; middle ear morphogenesis; nervous system development; retinal rod cell development; small molecule metabolic process,PF05089;PF12972;PF12971;,9.00E-15,CHOYP_NAGLU.2.2,,,,,,,ANAG_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] comp32974_c0_seq1,315,36.8254,1.04448168,0,21,,3.00E-16,P20678,Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (Cytochrome P450 PCHP7),Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (Cytochrome P450 PCHP7),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2H2_CHICK,Gallus gallus (Chicken),epoxygenase P450 pathway [GO:0019373] comp32984_c0_seq1,306,37.9085,0.91506193,14,0,,2.00E-21,Q62865,"cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)","cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)",GO:0004115; GO:0030552; GO:0006198; GO:0019933; GO:0004119; GO:0019934; GO:0071321; GO:0071560; GO:0005829; GO:0016101; GO:0016021; GO:0046872; GO:0043066; GO:0043116; GO:0001556; GO:0060282; GO:0043117; GO:0040020; GO:0051591; GO:0042493,"3',5'-cyclic-AMP phosphodiesterase activity; cAMP binding; cAMP catabolic process; cAMP-mediated signaling; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; cGMP-mediated signaling; cellular response to cGMP; cellular response to transforming growth factor beta stimulus; cytosol; diterpenoid metabolic process; integral to membrane; metal ion binding; negative regulation of apoptotic process; negative regulation of vascular permeability; oocyte maturation; positive regulation of oocyte development; positive regulation of vascular permeability; regulation of meiosis; response to cAMP; response to drug",PF00233;,2.00E-26,CHOYP_PDE3A.3.3,,,,,,,PDE3A_RAT,Rattus norvegicus (Rat),cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; diterpenoid metabolic process [GO:0016101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; response to cAMP [GO:0051591]; response to drug [GO:0042493] comp32999_c0_seq1,247,46.5587,0.33067209,8,6,,1.00E-08,Q66H54,FTS and Hook-interacting protein (FHIP) (Protein FAM160A2),FTS and Hook-interacting protein (FHIP) (Protein FAM160A2),GO:0070695; GO:0045022; GO:0007032; GO:0008333; GO:0007040; GO:0015031,FHF complex; early endosome to late endosome transport; endosome organization; endosome to lysosome transport; lysosome organization; protein transport,PF10257;,,,,,,,,,F16A2_RAT,Rattus norvegicus (Rat),early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; protein transport [GO:0015031] comp33006_c0_seq1,213,62.4413,0.97230676,3,8,,2.00E-18,Q6AB62,Thymidylate kinase (EC 2.7.4.9) (dTMP kinase),Thymidylate kinase (EC 2.7.4.9) (dTMP kinase),GO:0005524; GO:0006233; GO:0006235; GO:0004798,ATP binding; dTDP biosynthetic process; dTTP biosynthetic process; thymidylate kinase activity,,,,,,,,,,KTHY_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235] comp33049_c0_seq1,430,44.4186,0.47953085,14,0,,,,,,,,,1.00E-16,CHOYP_LOC100367864.2.3,,,,,,,,, comp33069_c0_seq1,238,42.437,0.65919209,7,15,,,,,,,,,4.00E-20,CHOYP_LOC100518275.1.1,,,,,,,,, comp33069_c1_seq1,303,45.5446,0.72641174,5,0,,7.00E-23,Q8I7Z8,Transcription factor hamlet,Transcription factor hamlet,GO:0003677; GO:0007219; GO:0048813; GO:0046872; GO:0005634; GO:0050773; GO:0003700; GO:0006351,"DNA binding; Notch signaling pathway; dendrite morphogenesis; metal ion binding; nucleus; regulation of dendrite development; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,2.00E-18,CHOYP_LOC664087.1.1,,,,,,,HAM_DROME,Drosophila melanogaster (Fruit fly),"dendrite morphogenesis [GO:0048813]; negative regulation of cell proliferation [GO:0008285]; neuroblast fate commitment [GO:0014017]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; regulation of dendrite development [GO:0050773]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp33128_c0_seq1,219,63.4703,1.0025064,0,8,,8.00E-17,A1W4M3,NADH-quinone oxidoreductase subunit B (EC 1.6.99.5) (NADH dehydrogenase I subunit B) (NDH-1 subunit B),NADH-quinone oxidoreductase subunit B (EC 1.6.5.11) (NADH dehydrogenase I subunit B) (NDH-1 subunit B),GO:0051539; GO:0008137; GO:0005506; GO:0005886; GO:0048038; GO:0006810,"4 iron, 4 sulfur cluster binding; NADH dehydrogenase (ubiquinone) activity; iron ion binding; plasma membrane; quinone binding; transport",PF01058;,,,,,,,,,NUOB_ACISJ,Acidovorax sp. (strain JS42),transport [GO:0006810] comp33161_c0_seq1,330,58.7879,0.73947488,0,20,,1.00E-08,P10056,Caricain (EC 3.4.22.30) (Papaya peptidase A) (Papaya proteinase III) (PPIII) (Papaya proteinase omega),Caricain (EC 3.4.22.30) (Papaya peptidase A) (Papaya proteinase III) (PPIII) (Papaya proteinase omega),GO:0008234; GO:0006508,cysteine-type peptidase activity; proteolysis,PF08246;PF00112;,,,,,,,,,PAPA3_CARPA,Carica papaya (Papaya), comp33184_c0_seq1,294,44.2177,1.06782123,0,16,,6.00E-08,Q8BS40,Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP),Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP),GO:0005794; GO:1902387; GO:1902389; GO:1902388; GO:0005829; GO:0010008; GO:0051861; GO:0046836; GO:0017089; GO:0005640; GO:0005886,Golgi apparatus; ceramide 1-phosphate binding; ceramide 1-phosphate transport; ceramide 1-phosphate transporter activity; cytosol; endosome membrane; glycolipid binding; glycolipid transport; glycolipid transporter activity; nuclear outer membrane; plasma membrane,PF08718;,,,4.00E-12,ruditapes_c31633,,,,,GLTD1_MOUSE,Mus musculus (Mouse),ceramide 1-phosphate transport [GO:1902389] comp33187_c0_seq1,654,42.2018,0.52127669,22,6,,7.00E-08,Q54KD0,TPR repeat-containing protein DDB_G0287407,TPR repeat-containing protein DDB_G0287407,GO:0017111; GO:0000166,nucleoside-triphosphatase activity; nucleotide binding,PF13271;,,,,,,,,,Y7407_DICDI,Dictyostelium discoideum (Slime mold), comp33207_c0_seq1,245,39.1837,0.21693483,3,3,,4.00E-09,Q6PB70,Anoctamin-8 (Transmembrane protein 16H),Anoctamin-8 (Transmembrane protein 16H),GO:0016021; GO:0005622; GO:0005886,integral to membrane; intracellular; plasma membrane,PF04547;,,,,,,,,,ANO8_MOUSE,Mus musculus (Mouse),chloride transport [GO:0006821] comp33214_c0_seq1,252,38.8889,0.5548333,7,7,,7.00E-11,Q8TDX7,Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7),Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7),GO:0005524; GO:0000910; GO:0005737; GO:0046872; GO:0005874; GO:0005815; GO:0005634; GO:0004674; GO:0007346; GO:0051225; GO:0000922,ATP binding; cytokinesis; cytoplasm; metal ion binding; microtubule; microtubule organizing center; nucleus; protein serine/threonine kinase activity; regulation of mitotic cell cycle; spindle assembly; spindle pole,PF00069;,,,9.00E-20,ruditapes_c25051,,,,,NEK7_HUMAN,Homo sapiens (Human),cytokinesis [GO:0000910]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] comp33215_c0_seq1,388,41.4948,0.42747537,9,14,,5.00E-28,B4J913,Facilitated trehalose transporter Tret1,Facilitated trehalose transporter Tret1,GO:0016021; GO:0005886; GO:0015574,integral to membrane; plasma membrane; trehalose transmembrane transporter activity,PF00083;,,,,,,,,,TRET1_DROGR,Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi),trehalose transport [GO:0015771] comp33237_c0_seq1,369,47.4255,0.82763766,6,10,,,,,,,,,,,6.00E-31,ruditapes_c16679,,,,,,, comp33243_c0_seq1,312,49.0385,0.9812013,3,12,,2.00E-16,P97402,"N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase)","N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase)",GO:0000139; GO:0008109; GO:0008375; GO:0016021; GO:0006486,"Golgi membrane; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity; integral to membrane; protein glycosylation",PF02485;,,,,,,,,,GCNT2_MOUSE,Mus musculus (Mouse),maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; posttranscriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp33244_c0_seq1,563,44.2274,0.55049627,17,12,,7.00E-71,Q923S9,Ras-related protein Rab-30,Ras-related protein Rab-30,GO:0005525; GO:0031985; GO:0007030; GO:0005801; GO:0016020; GO:0015031; GO:0007264; GO:0005802,GTP binding; Golgi cisterna; Golgi organization; cis-Golgi network; membrane; protein transport; small GTPase mediated signal transduction; trans-Golgi network,PF00071;,1.00E-56,CHOYP_LOC659383.2.2,5.00E-15,ruditapes_c7176,,,,,RAB30_MOUSE,Mus musculus (Mouse),Golgi organization [GO:0007030]; small GTPase mediated signal transduction [GO:0007264] comp33252_c0_seq1,221,42.5339,0.510825,7,0,,2.00E-16,Q9UGM3,Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein),Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein),GO:0048306; GO:0051607; GO:0030855; GO:0005576; GO:0019898; GO:0043152; GO:0045087; GO:0001833; GO:0019048; GO:0030670; GO:0030858; GO:0015031; GO:0005578; GO:0005044; GO:0008329; GO:0035375; GO:0042589,calcium-dependent protein binding; defense response to virus; epithelial cell differentiation; extracellular region; extrinsic to membrane; induction of bacterial agglutination; innate immune response; inner cell mass cell proliferation; modulation by virus of host morphology or physiology; phagocytic vesicle membrane; positive regulation of epithelial cell differentiation; protein transport; proteinaceous extracellular matrix; scavenger receptor activity; signaling pattern recognition receptor activity; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,,,,,,,,,DMBT1_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]; viral process [GO:0016032] comp33269_c0_seq1,419,50.8353,0.52566007,9,0,,2.00E-44,Q9R279,H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3),H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3),GO:0005524; GO:0005794; GO:0030165; GO:0015297; GO:0005769; GO:0031901; GO:0016021; GO:0005770; GO:0031902; GO:0030658; GO:0012506; GO:0005247,ATP binding; Golgi apparatus; PDZ domain binding; antiporter activity; early endosome; early endosome membrane; integral to membrane; late endosome; late endosome membrane; transport vesicle membrane; vesicle membrane; voltage-gated chloride channel activity,PF00571;PF00654;,1.00E-55,CHOYP_CLCN3.1.1,,,,,,,CLCN3_CAVPO,Cavia porcellus (Guinea pig), comp33281_c0_seq1,534,47.0037,0.98508282,22,8,,2.00E-33,Q6RI88,Electrogenic sodium bicarbonate cotransporter 4 (Solute carrier family 4 member 5),Electrogenic sodium bicarbonate cotransporter 4 (Solute carrier family 4 member 5),GO:0016323; GO:0005452; GO:0016021; GO:0006885; GO:0006814,basolateral plasma membrane; inorganic anion exchanger activity; integral to membrane; regulation of pH; sodium ion transport,PF07565;PF00955;,,,,,,,,,S4A5_RAT,Rattus norvegicus (Rat),anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; cerebrospinal fluid secretion [GO:0033326]; epithelial cell development [GO:0002064]; mitochondrion distribution [GO:0048311]; regulation of gene expression [GO:0010468]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; regulation of systemic arterial blood pressure [GO:0003073]; renal system process [GO:0003014]; retina development in camera-type eye [GO:0060041]; sodium ion transport [GO:0006814] comp33320_c0_seq1,216,43.5185,0.58968655,0,8,,2.00E-06,Q9VN14,Contactin,Contactin,GO:0031225; GO:0008366; GO:0030246; GO:0061343; GO:0060857; GO:0045197; GO:0021682; GO:0005886; GO:0005918; GO:0019991,anchored to membrane; axon ensheathment; carbohydrate binding; cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; establishment or maintenance of epithelial cell apical/basal polarity; nerve maturation; plasma membrane; septate junction; septate junction assembly,PF00041;PF00047;PF00059;,,,,,,,,,CONT_DROME,Drosophila melanogaster (Fruit fly),axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] comp33327_c0_seq1,216,43.5185,0.69046934,5,0,,1.00E-08,Q92521,GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B),GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B),GO:0006501; GO:0005789; GO:0016021; GO:0000030; GO:0016254,C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; mannosyltransferase activity; preassembly of GPI anchor in ER membrane,PF03901;,,,,,,,,,PIGB_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp33345_c0_seq1,217,46.5438,0.51700703,3,6,,2.00E-06,Q86TV6,Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),,,PF13181;,,,,,,,,,TTC7B_HUMAN,Homo sapiens (Human),establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854] comp33423_c0_seq1,240,68.3333,1.11709475,0,11,,4.00E-11,B8GAA4,6-phosphofructokinase (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase),ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase),GO:0003872; GO:0005945; GO:0005524; GO:0006002; GO:0006096; GO:0046872,6-phosphofructokinase activity; 6-phosphofructokinase complex; ATP binding; fructose 6-phosphate metabolic process; glycolysis; metal ion binding,PF00365;,,,,,,,,,K6PF_CHLAD,Chloroflexus aggregans (strain MD-66 / DSM 9485),fructose 6-phosphate metabolic process [GO:0006002] comp33435_c0_seq1,233,48.0687,0.53618009,0,17,,2.00E-06,O70244,Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),GO:0031526; GO:0005509; GO:0008203; GO:0031419; GO:0030666; GO:0010008; GO:0030492; GO:0020028; GO:0042802; GO:0001701; GO:0043202; GO:0005765; GO:0043234; GO:0070207; GO:0004872; GO:0006898; GO:0007584; GO:0006766,brush border membrane; calcium ion binding; cholesterol metabolic process; cobalamin binding; endocytic vesicle membrane; endosome membrane; hemoglobin binding; hemoglobin import; identical protein binding; in utero embryonic development; lysosomal lumen; lysosomal membrane; protein complex; protein homotrimerization; receptor activity; receptor-mediated endocytosis; response to nutrient; vitamin metabolic process,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_RAT,Rattus norvegicus (Rat),cholesterol metabolic process [GO:0008203]; cobalamin transport [GO:0015889]; hemoglobin import [GO:0020028]; in utero embryonic development [GO:0001701]; protein homotrimerization [GO:0070207]; receptor-mediated endocytosis [GO:0006898]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] comp33491_c0_seq1,495,38.1818,0.22217336,19,0,,1.00E-11,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp33531_c0_seq1,207,48.3092,0.08333528,1,8,,2.00E-13,Q99MU3,Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1),Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1),GO:0003723; GO:0006382; GO:0005737; GO:0051607; GO:0003726; GO:0031047; GO:0045087; GO:0003692; GO:0006397; GO:0046872; GO:0043066; GO:0044387; GO:0005730; GO:0045070; GO:0006611; GO:0006606; GO:0006355; GO:0035455; GO:0009615; GO:0044530; GO:0006351,"RNA binding; adenosine to inosine editing; cytoplasm; defense response to virus; double-stranded RNA adenosine deaminase activity; gene silencing by RNA; innate immune response; left-handed Z-DNA binding; mRNA processing; metal ion binding; negative regulation of apoptotic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; positive regulation of viral genome replication; protein export from nucleus; protein import into nucleus; regulation of transcription, DNA-dependent; response to interferon-alpha; response to virus; supraspliceosomal complex; transcription, DNA-dependent",PF02137;PF00035;PF02295;,,,,,,,,,DSRAD_MOUSE,Mus musculus (Mouse),"adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; transcription, DNA-templated [GO:0006351]" comp33562_c0_seq1,201,25.8706,0.93089862,2,8,,,,,,,,,,,3.00E-12,ruditapes2_c2493,,,,,,, comp33566_c0_seq1,393,40.9669,1.03556638,2,12,,2.00E-22,Q684R7,FRAS1-related extracellular matrix protein 1 (Protein QBRICK),FRAS1-related extracellular matrix protein 1 (Protein QBRICK),GO:0005604; GO:0030246; GO:0007154; GO:0007160; GO:0097094; GO:0016021; GO:0046872,basement membrane; carbohydrate binding; cell communication; cell-matrix adhesion; craniofacial suture morphogenesis; integral to membrane; metal ion binding,PF03160;PF00059;,8.00E-13,CHOYP_FREM1.1.1,,,,,,,FREM1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] comp33644_c0_seq1,325,46.1538,0.81369998,1,51,,9.00E-14,P26262,Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain],GO:0007596; GO:0005576; GO:0042730; GO:0006954; GO:0006508; GO:0004252,blood coagulation; extracellular region; fibrinolysis; inflammatory response; proteolysis; serine-type endopeptidase activity,PF00024;PF00089;,,,4.00E-64,ruditapes_lrc33051,,,,,KLKB1_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919] comp33662_c0_seq1,265,42.6415,0.35349341,12,0,,9.00E-30,Q9CXF7,Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),GO:0005524; GO:0016887; GO:0003677; GO:0006281; GO:0006338; GO:0004386; GO:0000166; GO:0005634; GO:0006974,ATP binding; ATPase activity; DNA binding; DNA repair; chromatin remodeling; helicase activity; nucleotide binding; nucleus; response to DNA damage stimulus,PF00271;PF00176;,,,,,,,,,CHD1L_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] comp33683_c0_seq1,223,48.8789,0.57437052,1,0,,5.00E-06,P35352,Cyclic AMP receptor 3 (cAMP receptor 3),Cyclic AMP receptor 3 (cAMP receptor 3),GO:0004930; GO:0032861; GO:0007190; GO:0031152; GO:0030552; GO:0001646; GO:0006935; GO:0005887,G-protein coupled receptor activity; activation of Rap GTPase activity; activation of adenylate cyclase activity; aggregation involved in sorocarp development; cAMP binding; cAMP receptor activity; chemotaxis; integral to plasma membrane,,,,,,,,,,CAR3_DICDI,Dictyostelium discoideum (Slime mold),activation of adenylate cyclase activity [GO:0007190]; activation of GTPase activity [GO:0090630]; aggregation involved in sorocarp development [GO:0031152]; cAMP-mediated signaling [GO:0019933]; cGMP-mediated signaling [GO:0019934]; chemotaxis [GO:0006935]; regulation of Ras protein signal transduction [GO:0046578] comp33688_c0_seq1,248,46.7742,0.59233791,5,9,,4.00E-25,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,1.00E-20,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp33689_c0_seq1,269,57.2491,1.27855648,6,7,,1.00E-41,P13567,UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A),UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A),GO:0005524; GO:0006200; GO:0043190; GO:0016887; GO:0003677; GO:0009432; GO:0005737; GO:0009381; GO:0009380; GO:0090305; GO:0006289; GO:0006810; GO:0008270,ATP binding; ATP catabolic process; ATP-binding cassette (ABC) transporter complex; ATPase activity; DNA binding; SOS response; cytoplasm; excinuclease ABC activity; excinuclease repair complex; nucleic acid phosphodiester bond hydrolysis; nucleotide-excision repair; transport; zinc ion binding,PF00005;,,,,,,,,,UVRA_MICLU,Micrococcus luteus (Micrococcus lysodeikticus),nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432] comp33694_c0_seq1,331,44.713,0.72967699,9,12,,4.00E-07,Q9DC26,Solute carrier family 46 member 3,Solute carrier family 46 member 3,GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,S46A3_MOUSE,Mus musculus (Mouse),transmembrane transport [GO:0055085] comp33700_c0_seq1,305,41.6393,0.38003389,7,9,,1.00E-37,Q4L208,Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8),Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8),GO:0000139; GO:0016021; GO:0006885; GO:0015385,Golgi membrane; integral to membrane; regulation of pH; sodium:hydrogen antiporter activity,PF00999;,4.00E-53,CHOYP_LOC578765.1.1,,,,,,,SL9A8_RAT,Rattus norvegicus (Rat),regulation of pH [GO:0006885] comp33759_c0_seq1,216,42.1296,0.73596539,1,18,,,,,,,,,4.00E-13,CHOYP_BRAFLDRAFT_208436.24.32,,,,,,,,, comp33765_c0_seq1,262,44.2748,0.24033247,1,13,,2.00E-21,Q9Y2I1,Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein),Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein),GO:0008227; GO:0016601; GO:0030036; GO:0006915; GO:0005829; GO:0005769; GO:0006006; GO:0030336; GO:0048243; GO:0035091; GO:0005886; GO:0055037; GO:0008217; GO:0032228,"G-protein coupled amine receptor activity; Rac protein signal transduction; actin cytoskeleton organization; apoptotic process; cytosol; early endosome; glucose metabolic process; negative regulation of cell migration; norepinephrine secretion; phosphatidylinositol binding; plasma membrane; recycling endosome; regulation of blood pressure; regulation of synaptic transmission, GABAergic",PF00787;,,,,,,,,,NISCH_HUMAN,Homo sapiens (Human),"actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]" comp33777_c0_seq1,226,40.708,0.10773823,6,7,,2.00E-14,P10611,Cytochrome P450 4A4 (EC 1.14.14.1) (CYPIVA4) (Cytochrome P450-P-2) (Prostaglandin omega-hydroxylase),Cytochrome P450 4A4 (EC 1.14.14.1) (CYPIVA4) (Cytochrome P450-P-2) (Prostaglandin omega-hydroxylase),GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding,PF00067;,,,,,,,,,CP4A4_RABIT,Oryctolagus cuniculus (Rabbit), comp33783_c0_seq1,336,47.9167,0.98904182,2,22,,,,,,,,,6.00E-13,CHOYP_LOC100641969.1.1,,,,,,,,, comp33815_c0_seq1,204,77.451,1.15430702,0,9,,1.00E-09,C0SP82,Probable oxidoreductase YoaE (EC 1.-.-.-),Probable oxidoreductase YoaE (EC 1.-.-.-),GO:0009055; GO:0051536; GO:0030151; GO:0016491,electron carrier activity; iron-sulfur cluster binding; molybdenum ion binding; oxidoreductase activity,PF04879;PF00384;PF01568;,,,,,,,,,YOAE_BACSU,Bacillus subtilis (strain 168), comp33835_c0_seq1,224,45.0893,0.62800295,2,5,,2.00E-10,Q6XUX0,Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),GO:0005524; GO:0005737; GO:0018108; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00069;,4.00E-19,CHOYP_LOC100370896.4.4,,,,,,,DUSTY_CHICK,Gallus gallus (Chicken),intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp33841_c0_seq1,284,39.0845,0.65410647,6,5,,1.00E-19,A6H7B8,Post-GPI attachment to proteins factor 2,Post-GPI attachment to proteins factor 2,GO:0006506; GO:0000139; GO:0005789; GO:0016021; GO:0008565,GPI anchor biosynthetic process; Golgi membrane; endoplasmic reticulum membrane; integral to membrane; protein transporter activity,PF10277;,,,,,,,,,PGAP2_BOVIN,Bos taurus (Bovine),GPI anchor biosynthetic process [GO:0006506]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; signal transduction in response to DNA damage [GO:0042770] comp33885_c0_seq1,222,60.3604,1.04671096,0,13,,2.00E-25,Q10530,Citrate synthase 1 (EC 2.3.3.1),,GO:0044262; GO:0004108; GO:0005829; GO:0005886; GO:0006099,cellular carbohydrate metabolic process; citrate (Si)-synthase activity; cytosol; plasma membrane; tricarboxylic acid cycle,,,,,,,,,,CISY1_MYCTU,, comp33923_c0_seq1,359,39.8329,0.49842159,12,3,,6.00E-30,O14657,Torsin-1B (Torsin family 1 member B),Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B),GO:0005524; GO:0051085; GO:0005788; GO:0005635; GO:0071763; GO:0017111; GO:0051260; GO:0006986; GO:0051082,ATP binding; chaperone mediated protein folding requiring cofactor; endoplasmic reticulum lumen; nuclear envelope; nuclear membrane organization; nucleoside-triphosphatase activity; protein homooligomerization; response to unfolded protein; unfolded protein binding,PF06309;,3.00E-30,CHOYP_BRAFLDRAFT_128102.1.1,,,,,,,TOR1B_HUMAN,Homo sapiens (Human),chaperone mediated protein folding requiring cofactor [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein homooligomerization [GO:0051260]; response to unfolded protein [GO:0006986] comp33941_c0_seq1,229,46.2882,0.42451898,2,13,,2.00E-07,Q7Z2H8,Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1),Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1),GO:0015180; GO:0015193; GO:0006865; GO:0005783; GO:0015187; GO:0015078; GO:0016021; GO:0005765; GO:0005886; GO:0015293; GO:0055085,L-alanine transmembrane transporter activity; L-proline transmembrane transporter activity; amino acid transport; endoplasmic reticulum; glycine transmembrane transporter activity; hydrogen ion transmembrane transporter activity; integral to membrane; lysosomal membrane; plasma membrane; symporter activity; transmembrane transport,PF01490;,2.00E-17,CHOYP_LOC100892108.1.1,,,,,,,S36A1_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; glycine transport [GO:0015816]; ion transport [GO:0006811] comp33962_c0_seq1,322,31.3665,0.39713498,4,23,,3.00E-11,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,,,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp33988_c0_seq1,221,61.991,1.1833931,0,8,,2.00E-08,Q9X8Z9,Potassium-transporting ATPase B chain (EC 3.6.3.12) (ATP phosphohydrolase [potassium-transporting] B chain) (Potassium-binding and translocating subunit B) (Potassium-translocating ATPase B chain),Potassium-transporting ATPase ATP-binding subunit (EC 3.6.3.12) (ATP phosphohydrolase [potassium-transporting] B chain) (Potassium-binding and translocating subunit B) (Potassium-translocating ATPase B chain),GO:0005524; GO:0016021; GO:0000287; GO:0005886; GO:0008556,ATP binding; integral to membrane; magnesium ion binding; plasma membrane; potassium-transporting ATPase activity,PF00122;,,,,,,,,,ATKB_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145), comp34023_c0_seq1,613,48.2871,0.50912242,12,26,,8.00E-13,Q99MU3,Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1),Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1),GO:0003723; GO:0006382; GO:0005737; GO:0051607; GO:0003726; GO:0031047; GO:0045087; GO:0003692; GO:0006397; GO:0046872; GO:0043066; GO:0044387; GO:0005730; GO:0045070; GO:0006611; GO:0006606; GO:0006355; GO:0035455; GO:0009615; GO:0044530; GO:0006351,"RNA binding; adenosine to inosine editing; cytoplasm; defense response to virus; double-stranded RNA adenosine deaminase activity; gene silencing by RNA; innate immune response; left-handed Z-DNA binding; mRNA processing; metal ion binding; negative regulation of apoptotic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; nucleolus; positive regulation of viral genome replication; protein export from nucleus; protein import into nucleus; regulation of transcription, DNA-dependent; response to interferon-alpha; response to virus; supraspliceosomal complex; transcription, DNA-dependent",PF02137;PF00035;PF02295;,,,,,,,,,DSRAD_MOUSE,Mus musculus (Mouse),"adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; transcription, DNA-templated [GO:0006351]" comp34024_c0_seq1,479,43.0063,0.65116563,7,20,,9.00E-43,Q8N264,Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP),Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP),GO:0030675; GO:0032863; GO:0001525; GO:0030154; GO:0042995; GO:0005856; GO:0005829; GO:0005925; GO:0035021; GO:1900028; GO:0005543; GO:0005886; GO:0051056; GO:0007264; GO:0035313,"Rac GTPase activator activity; activation of Rac GTPase activity; angiogenesis; cell differentiation; cell projection; cytoskeleton; cytosol; focal adhesion; negative regulation of Rac protein signal transduction; negative regulation of ruffle assembly; phospholipid binding; plasma membrane; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; wound healing, spreading of epidermal cells",PF00169;PF00620;,,,,,,,,,RHG24_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp34031_c0_seq1,378,41.5344,0.30903674,2,8,,1.00E-20,Q1M4T3,Pseudouridine-5'-phosphate glycosidase 2 (PsiMP glycosidase 2) (EC 3.2.-.-),Pseudouridine-5'-phosphate glycosidase 2 (PsiMP glycosidase 2) (EC 4.2.1.70),GO:0016798; GO:0046872,"hydrolase activity, acting on glycosyl bonds; metal ion binding",PF04227;,,,,,,,,,PSUG2_RHIL3,Rhizobium leguminosarum bv. viciae (strain 3841),nucleobase catabolic process [GO:0046113] comp34034_c0_seq1,356,49.4382,0.56044398,5,13,,4.00E-39,Q9UHW9,Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),GO:0001525; GO:0016323; GO:0071477; GO:0016021; GO:0006813; GO:0015379,angiogenesis; basolateral plasma membrane; cellular hypotonic salinity response; integral to membrane; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,2.00E-46,CHOYP_DWIL_GK15715.1.1,,,,,,,S12A6_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826] comp34044_c0_seq1,202,40.099,0.61891761,3,10,,7.00E-24,Q9H237,Protein-cysteine N-palmitoyltransferase porcupine (EC 2.3.1.-) (Protein MG61),Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.-) (Protein MG61),GO:0016055; GO:0032281; GO:0009100; GO:0030176; GO:0016746,"Wnt receptor signaling pathway; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; glycoprotein metabolic process; integral to endoplasmic reticulum membrane; transferase activity, transferring acyl groups",PF03062;,4.00E-19,CHOYP_LOC577959.1.2,,,,,,,PORCN_HUMAN,Homo sapiens (Human),canonical Wnt signaling pathway [GO:0060070]; glycoprotein metabolic process [GO:0009100]; protein lipidation [GO:0006497]; protein palmitoleylation [GO:0045234]; Wnt signaling pathway [GO:0016055] comp34051_c0_seq1,456,41.886,0.25110011,16,3,,2.00E-12,Q8BR76,Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67),Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67),GO:0036038; GO:0048754; GO:0042384; GO:0030659; GO:0005789; GO:0016021; GO:0005932; GO:0010826; GO:0005886,TCTN-B9D complex; branching morphogenesis of an epithelial tube; cilium assembly; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; integral to membrane; microtubule basal body; negative regulation of centrosome duplication; plasma membrane,PF09773;,,,,,,,,,MKS3_MOUSE,Mus musculus (Mouse),branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; heart development [GO:0007507]; negative regulation of centrosome duplication [GO:0010826] comp34072_c0_seq1,282,42.1986,1.05598343,0,29,,,,,,,,,1.00E-28,CHOYP_NEMVEDRAFT_V1G86755.1.1,,,,,,,,, comp34088_c0_seq2,241,49.3776,0.27345104,2,0,,1.00E-15,D4A929,WD repeat-containing protein 81,WD repeat-containing protein 81,GO:0010923; GO:0016772,"negative regulation of phosphatase activity; transferase activity, transferring phosphorus-containing groups",PF02138;PF00400;,,,,,,,,,WDR81_RAT,Rattus norvegicus (Rat),establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; negative regulation of phosphatase activity [GO:0010923]; neurogenesis [GO:0022008]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496] comp34104_c0_seq1,248,51.2097,0.1244398,3,10,,,,,,,,,4.00E-27,CHOYP_BRAFLDRAFT_82864.1.1,,,,,,,,, comp34126_c0_seq1,471,39.9151,0.62165031,22,3,,7.00E-62,F1MH24,AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1),AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1),GO:0035612; GO:0005524; GO:0005112; GO:0031252; GO:0030136; GO:0005905; GO:0006897; GO:0019897; GO:0045747; GO:0046777; GO:0004674; GO:0050821; GO:2000369; GO:0032880; GO:0043195,AP-2 adaptor complex binding; ATP binding; Notch binding; cell leading edge; clathrin-coated vesicle; coated pit; endocytosis; extrinsic to plasma membrane; positive regulation of Notch signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein stabilization; regulation of clathrin-mediated endocytosis; regulation of protein localization; terminal bouton,PF00069;,4.00E-74,CHOYP_AAK1.1.1,,,,,,,AAK1_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of protein localization [GO:0032880] comp34152_c0_seq1,225,39.5556,0.344519,5,0,,9.00E-08,P10419,Antho-RFamide neuropeptides type 1 [Cleaved into: Antho-RFamide],Antho-RFamide neuropeptides type 1 [Cleaved into: Antho-RFamide],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,,,,,,,,,FMR1_ANTEL,Anthopleura elegantissima (Sea anemone),neuropeptide signaling pathway [GO:0007218] comp34154_c0_seq1,297,43.0976,0.73040044,0,16,,2.00E-47,Q7KVW5,Small conductance calcium-activated potassium channel protein (Protein SK) (dSK),Small conductance calcium-activated potassium channel protein (Protein SK) (dSK),GO:0016021; GO:0009881; GO:0016057; GO:0016286,integral to membrane; photoreceptor activity; regulation of membrane potential in photoreceptor cell; small conductance calcium-activated potassium channel activity,PF02888;PF07885;PF03530;,2.00E-31,CHOYP_DGRI_GH24618.2.2,,,,,,,KCNN_DROME,Drosophila melanogaster (Fruit fly),potassium ion transport [GO:0006813]; regulation of membrane potential in photoreceptor cell [GO:0016057] comp34170_c0_seq1,684,44.5906,0.26823065,44,33,,6.00E-76,Q7Z3C6,Autophagy-related protein 9A (APG9-like 1) (mATG9),Autophagy-related protein 9A (APG9-like 1) (mATG9),GO:0005794; GO:0000045; GO:0000421; GO:0031410; GO:0005789; GO:0045087; GO:0016021; GO:0031902; GO:0034067; GO:0015031,Golgi apparatus; autophagic vacuole assembly; autophagic vacuole membrane; cytoplasmic vesicle; endoplasmic reticulum membrane; innate immune response; integral to membrane; late endosome membrane; protein localization to Golgi apparatus; protein transport,PF04109;,6.00E-36,CHOYP_LOC100561934.1.1,,,,,,,ATG9A_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein localization to pre-autophagosomal structure [GO:0034497]; protein transport [GO:0015031] comp34206_c0_seq1,327,57.1865,1.16339761,0,25,,6.00E-16,Q47162,Ferrichrysobactin receptor,Ferrichrysobactin receptor,GO:0009279; GO:0016021; GO:0005506; GO:0004872; GO:0044718; GO:0015343,cell outer membrane; integral to membrane; iron ion binding; receptor activity; siderophore transmembrane transport; siderophore transmembrane transporter activity,PF07715;PF00593;,,,,,,,,,FCT_DICD3,Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; siderophore transport [GO:0015891] comp34214_c0_seq1,265,46.7925,0.49065257,7,7,,1.00E-09,Q7Z5J8,Ankyrin and armadillo repeat-containing protein,Ankyrin and armadillo repeat-containing protein,GO:0016021,integral to membrane,PF12796;PF00514;,,,,,,,,,ANKAR_HUMAN,Homo sapiens (Human), comp34223_c0_seq1,318,49.0566,0.15753242,2,11,,9.00E-28,P0C091,FRAS1-related extracellular matrix protein 3,FRAS1-related extracellular matrix protein 3,GO:0005604; GO:0007155; GO:0007154; GO:0016021; GO:0046872,basement membrane; cell adhesion; cell communication; integral to membrane; metal ion binding,PF03160;,,,,,,,,,FREM3_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154] comp34244_c0_seq1,239,61.5063,1.12953785,1,12,,1.00E-20,O53226,Putative peroxiredoxin Rv2521/MT2597 (EC 1.11.1.15) (Bacterioferritin comigratory protein) (Thioredoxin reductase),,GO:0005829; GO:0004601; GO:0051920; GO:0005886,cytosol; peroxidase activity; peroxiredoxin activity; plasma membrane,,,,,,,,,,BCP_MYCTU,, comp34262_c0_seq1,243,43.2099,0.54546378,1,7,,2.00E-22,Q4VBI7,Syntaxin-18,Syntaxin-18,GO:0005789; GO:0016021; GO:0006886; GO:0016192,endoplasmic reticulum membrane; integral to membrane; intracellular protein transport; vesicle-mediated transport,PF10496;,,,,,,,,,STX18_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp34276_c0_seq1,265,45.283,0.60181852,2,11,,1.00E-11,Q19319,Cadherin-4,Cadherin-4,GO:0007411; GO:0005509; GO:0007163; GO:0007156; GO:0016021; GO:0005886,axon guidance; calcium ion binding; establishment or maintenance of cell polarity; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,CADH4_CAEEL,Caenorhabditis elegans,axon guidance [GO:0007411]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuroblast migration [GO:0097402] comp3427_c0_seq1,633,41.5482,0.44616579,14,0,,2.00E-39,Q9UBZ9,DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase),DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase),GO:0006260; GO:0003887; GO:0003684; GO:0017125; GO:0042276; GO:0000287; GO:0005654; GO:0009411,DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; deoxycytidyl transferase activity; error-prone translesion synthesis; magnesium ion binding; nucleoplasm; response to UV,PF16589;PF14377;PF00817;PF11799;PF16727;,,,,,,,,,REV1_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] comp34280_c0_seq1,221,40.2715,0.44985723,6,3,,3.00E-11,Q8NB14,Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38),Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP38_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp34311_c0_seq1,211,37.9147,0.40381859,0,9,,,,,,,,,2.00E-16,CHOYP_LOC100891447.1.1,,,,,,,,, comp34317_c0_seq1,284,46.831,0.64744101,0,27,,8.00E-06,Q9VJB6,Putative neural-cadherin 2 (Cadherin-N2) (dN2-cadherin),Putative neural-cadherin 2 (Cadherin-N2) (dN2-cadherin),GO:0045467; GO:0045463; GO:0048846; GO:0005509; GO:0016339; GO:0050839; GO:0007156; GO:0005887; GO:0016318; GO:0004872,R7 cell development; R8 cell development; axon extension involved in axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; homophilic cell adhesion; integral to plasma membrane; ommatidial rotation; receptor activity,PF00028;PF01049;PF00008;PF02210;,,,,,,,,,CADN2_DROME,Drosophila melanogaster (Fruit fly),axon extension involved in axon guidance [GO:0048846]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463] comp34359_c0_seq1,1048,47.3282,0.93469163,43,16,,2.00E-12,Q9P2S2,Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha),Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha),GO:0005246; GO:0007155; GO:0050839; GO:0097116; GO:0016021; GO:0046872; GO:0097118; GO:0097109; GO:0007269; GO:0097119; GO:0097104,calcium channel regulator activity; cell adhesion; cell adhesion molecule binding; gephyrin clustering; integral to membrane; metal ion binding; neuroligin clustering; neuroligin family protein binding; neurotransmitter secretion; postsynaptic density protein 95 clustering; postsynaptic membrane assembly,PF00054;PF02210;PF01034;,,,,,,,,,NRX2A_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter secretion [GO:0007269]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]; vocal learning [GO:0042297] comp34378_c0_seq1,336,46.131,0.40912607,15,0,,1.00E-56,Q9R1S3,GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GO:0006506; GO:0005789; GO:0016021; GO:0016780,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; phosphotransferase activity, for other substituted phosphate groups",PF01663;PF04987;,9.00E-62,CHOYP_PIGN.1.1,,,,,,,PIGN_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp34391_c0_seq1,208,37.5,0.27555021,1,13,,4.00E-08,Q3V0M2,Leucine-rich repeat-containing protein 36,Leucine-rich repeat-containing protein 36,,,,6.00E-23,CHOYP_LOC100375747.1.1,,,,,,,LRC36_MOUSE,Mus musculus (Mouse), comp34430_c0_seq1,224,53.125,1.01869602,0,10,,4.00E-07,O34518,Putative ABC transporter permease protein AmyC,Putative ABC transporter permease protein AmyC,GO:0016021; GO:0005886; GO:0005215,integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,AMYC_BACSU,Bacillus subtilis (strain 168),transport [GO:0006810] comp34444_c0_seq1,250,45.6,0.79231066,1,16,,1.00E-14,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp34467_c0_seq1,671,40.3875,0.48297321,19,2,,9.00E-22,Q06527,Ankyrin homolog,Ankyrin homolog,,,PF12796;,,,,,,,,,ANKH_ALLVD,Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum), comp34491_c0_seq1,384,42.7083,0.93291561,8,54,,6.00E-12,P49910,Zinc finger protein 165 (Cancer/testis antigen 53) (CT53) (LD65) (Zinc finger and SCAN domain-containing protein 7),Zinc finger protein 165 (Cancer/testis antigen 53) (CT53) (LD65) (Zinc finger and SCAN domain-containing protein 7),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;,,,,,,,,,ZN165_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp34493_c0_seq1,290,46.2069,0.33487165,8,5,,6.00E-06,Q8CCC3,Uncharacterized protein C12orf56 homolog,Uncharacterized protein C12orf56 homolog,,,PF15087;,,,,,,,,,CL056_MOUSE,Mus musculus (Mouse), comp34499_c0_seq1,263,48.6692,1.11311133,0,32,,9.00E-20,P15428,15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1),15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1),GO:0016404; GO:0070403; GO:0019371; GO:0005829; GO:0097070; GO:0007565; GO:2001300; GO:0019372; GO:0045786; GO:0005634; GO:0030728; GO:0007567; GO:0004957; GO:0042803; GO:0070493; GO:0007179,15-hydroxyprostaglandin dehydrogenase (NAD+) activity; NAD+ binding; cyclooxygenase pathway; cytosol; ductus arteriosus closure; female pregnancy; lipoxin metabolic process; lipoxygenase pathway; negative regulation of cell cycle; nucleus; ovulation; parturition; prostaglandin E receptor activity; protein homodimerization activity; thrombin receptor signaling pathway; transforming growth factor beta receptor signaling pathway,PF00106;,2.00E-11,CHOYP_HPGD.1.3,,,,,,,PGDH_HUMAN,Homo sapiens (Human),ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; lipoxin metabolic process [GO:2001300]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; thrombin receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp34500_c0_seq1,224,61.6071,1.25002491,1,15,,2.00E-10,P37391,Bifunctional NAD(P)H-hydrate repair enzyme Nnr (Nicotinamide nucleotide repair protein) [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)],Bifunctional NAD(P)H-hydrate repair enzyme Nnr (Nicotinamide nucleotide repair protein) [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)],GO:0005524; GO:0016853; GO:0016829; GO:0046872,ATP binding; isomerase activity; lyase activity; metal ion binding,PF01256;PF03853;,,,,,,,,,NNR_MYCLE,Mycobacterium leprae (strain TN),metabolic process [GO:0008152] comp34502_c0_seq1,227,63.8767,0.95435642,0,11,,3.00E-07,P55183,Sensor histidine kinase YxjM (EC 2.7.13.3),Sensor histidine kinase YxjM (EC 2.7.13.3),GO:0005524; GO:0016021; GO:0018106; GO:0000155; GO:0005886; GO:0023014,ATP binding; integral to membrane; peptidyl-histidine phosphorylation; phosphorelay sensor kinase activity; plasma membrane; signal transduction by phosphorylation,PF07730;,,,,,,,,,YXJM_BACSU,Bacillus subtilis (strain 168), comp34506_c0_seq1,409,42.0538,0.60117661,15,6,,3.00E-49,P13706,"Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)","Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)",GO:0031430; GO:0051287; GO:0030018; GO:0005975; GO:0007629; GO:0046168; GO:0004367; GO:0009331; GO:0006650; GO:0005811; GO:0006641,M band; NAD binding; Z disc; carbohydrate metabolic process; flight behavior; glycerol-3-phosphate catabolic process; glycerol-3-phosphate dehydrogenase [NAD+] activity; glycerol-3-phosphate dehydrogenase complex; glycerophospholipid metabolic process; lipid particle; triglyceride metabolic process,PF07479;PF01210;,3.00E-25,CHOYP_GPDA.1.2,8.00E-17,ruditapes_c25968,,,,,GPDA_DROME,Drosophila melanogaster (Fruit fly),carbohydrate metabolic process [GO:0005975]; ethanol metabolic process [GO:0006067]; flight behavior [GO:0007629]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophosphate shuttle [GO:0006127]; glycerophospholipid metabolic process [GO:0006650]; triglyceride metabolic process [GO:0006641] comp34526_c0_seq1,221,38.009,0.76202933,2,6,,7.00E-26,Q9NU19,TBC1 domain family member 22B,TBC1 domain family member 22B,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,6.00E-30,CHOYP_TBC1D22A.1.1,,,,,,,TB22B_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp34565_c0_seq1,285,60,0.97973253,0,15,,3.00E-45,Q945U1,40S ribosomal protein S15,40S ribosomal protein S15,GO:0003723; GO:0015935; GO:0003735; GO:0006412,RNA binding; small ribosomal subunit; structural constituent of ribosome; translation,PF00203;,,,,,,,,,RS15_ELAOL,Elaeis oleifera (American oil palm) (Corozo oleifera),translation [GO:0006412] comp34576_c1_seq1,221,68.7783,1.20845319,0,14,,2.00E-17,Q39654,"Photosystem I reaction center subunit XI, chloroplastic (PSI-L) (PSI subunit V)","Photosystem I reaction center subunit XI, chloroplastic (PSI-L) (PSI subunit V)",GO:0009535; GO:0016021; GO:0015979; GO:0009538,chloroplast thylakoid membrane; integral to membrane; photosynthesis; photosystem I reaction center,PF02605;,,,,,,,,,PSAL_CUCSA,Cucumis sativus (Cucumber),photosynthesis [GO:0015979] comp34578_c0_seq1,248,49.1935,0.53534867,2,10,,2.00E-12,Q53HC5,Kelch-like protein 26,Kelch-like protein 26,,,PF07707;PF00651;PF01344;,1.00E-26,CHOYP_LOC101071980.1.1,,,,,,,KLH26_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp34593_c0_seq1,267,39.7004,0.95715628,5,9,,4.00E-31,Q9P1Q0,Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p),Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p),GO:0000938; GO:0040007; GO:0048873; GO:0050881; GO:0060052; GO:0015031; GO:0042147,"GARP complex; growth; homeostasis of number of cells within a tissue; musculoskeletal movement; neurofilament cytoskeleton organization; protein transport; retrograde transport, endosome to Golgi",PF07928;PF10475;,,,,,,,,,VPS54_HUMAN,Homo sapiens (Human),"Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp34634_c0_seq1,209,59.8086,1.0758443,0,8,,7.00E-43,Q6AAX3,Phosphate import ATP-binding protein PstB (EC 3.6.3.27) (ABC phosphate transporter) (Phosphate-transporting ATPase),Phosphate import ATP-binding protein PstB (EC 3.6.3.27) (ABC phosphate transporter) (Phosphate-transporting ATPase),GO:0005524; GO:0006200; GO:0005315; GO:0015415; GO:0005886,ATP binding; ATP catabolic process; inorganic phosphate transmembrane transporter activity; phosphate ion transmembrane-transporting ATPase activity; plasma membrane,PF00005;,,,,,,,,,PSTB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp34637_c0_seq1,328,38.7195,0.41730474,2,21,,2.00E-36,Q6NUD4,Putative hydroxypyruvate isomerase (EC 5.3.1.22),Putative hydroxypyruvate isomerase (EC 5.3.1.22),GO:0008903,hydroxypyruvate isomerase activity,PF01261;,,,,,,,,,HYI_XENLA,Xenopus laevis (African clawed frog), comp34667_c0_seq1,695,41.1511,0.80180482,14,17,,4.00E-10,Q99676,Zinc finger protein 184,Zinc finger protein 184,GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZN184_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp34682_c0_seq1,206,37.3786,0.70795102,2,2,,1.00E-13,Q8BM47,Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3),Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3),GO:0035556; GO:0046872; GO:0005543,intracellular signal transduction; metal ion binding; phospholipid binding,PF00169;PF13901;,6.00E-23,CHOYP_PKHM1.1.1,,,,,,,PKHM3_MOUSE,Mus musculus (Mouse), comp34683_c0_seq1,240,42.0833,0.47292815,7,6,,3.00E-08,P31792,Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)] (Fragment),Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (Fragment),GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0075713; GO:0090305; GO:0004523; GO:0046718,DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; viral entry into host cell,PF00075;PF00665;PF00078;PF09337;,2.00E-12,CHOYP_contig_006627,,,,,,,POL_FENV1,Feline endogenous virus ECE1,DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp34688_c0_seq1,244,45.082,0.25128627,7,6,,4.00E-20,P24386,Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein),Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein),GO:0005096; GO:0004663; GO:0005968; GO:0001568; GO:0006886; GO:0043547; GO:0018344; GO:0050896; GO:0007601,GTPase activator activity; Rab geranylgeranyltransferase activity; Rab-protein geranylgeranyltransferase complex; blood vessel development; intracellular protein transport; positive regulation of GTPase activity; protein geranylgeranylation; response to stimulus; visual perception,PF00996;,,,,,,,,,RAE1_HUMAN,Homo sapiens (Human),protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; regulation of apoptotic process [GO:0042981]; small GTPase mediated signal transduction [GO:0007264]; visual perception [GO:0007601] comp34700_c0_seq1,238,42.0168,0.4810874,2,7,,2.00E-28,P42695,Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3),Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3),GO:0051301; GO:0035064; GO:0007076; GO:0031618; GO:0000799,cell division; methylated histone residue binding; mitotic chromosome condensation; nuclear centromeric heterochromatin; nuclear condensin complex,PF12717;,,,,,,,,,CNDD3_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076] comp34722_c0_seq1,286,54.1958,1.1549437,0,14,,1.00E-06,P14827,Modification methylase EcaI (M.EcaI) (EC 2.1.1.72) (Adenine-specific methyltransferase EcaI),Modification methylase EcaI (M.EcaI) (EC 2.1.1.72) (Adenine-specific methyltransferase EcaI),GO:0003677; GO:0032775; GO:0009307; GO:0008170; GO:0009007,DNA binding; DNA methylation on adenine; DNA restriction-modification system; N-methyltransferase activity; site-specific DNA-methyltransferase (adenine-specific) activity,PF01555;,,,,,,,,,MTEC_ENTCL,Enterobacter cloacae,DNA restriction-modification system [GO:0009307] comp34747_c0_seq1,342,44.152,1.1579701,9,7,,5.00E-26,Q29RY7,Fibroleukin (Fibrinogen-like protein 2),Fibroleukin (Fibrinogen-like protein 2),GO:0009986; GO:0005576; GO:0016504,cell surface; extracellular region; peptidase activator activity,PF00147;,,,,,,,,,FGL2_BOVIN,Bos taurus (Bovine), comp34750_c0_seq1,218,42.2018,0.11248311,3,4,,2.00E-10,Q6JAN0,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),GO:0004930; GO:0042462; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; eye photoreceptor cell development; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF03160;,,,,,,,,,GPR98_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462] comp34774_c0_seq1,266,42.8571,0.2648847,2,7,,4.00E-35,Q1JPD3,"D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)","D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)",GO:0008762; GO:0050660; GO:0005739,UDP-N-acetylmuramate dehydrogenase activity; flavin adenine dinucleotide binding; mitochondrion,PF02913;PF01565;,1.00E-34,CHOYP_LOC100367659.1.1,,,,,,,D2HDH_BOVIN,Bos taurus (Bovine), comp34790_c0_seq1,205,43.9024,0.30534323,4,2,,3.00E-10,P52429,Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon),Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon),GO:0005524; GO:0003951; GO:0005737; GO:0004143; GO:0016021; GO:0035556; GO:0046872; GO:0008654; GO:0005886; GO:0030168; GO:0007205,ATP binding; NAD+ kinase activity; cytoplasm; diacylglycerol kinase activity; integral to membrane; intracellular signal transduction; metal ion binding; phospholipid biosynthetic process; plasma membrane; platelet activation; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF00609;PF00781;,6.00E-11,CHOYP_ISCW_ISCW016328.1.1,,,,,,,DGKE_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; phospholipid biosynthetic process [GO:0008654]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205] comp34793_c0_seq1,228,50.8772,0.41040216,2,5,,9.00E-15,Q9ULX7,Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV),Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV),GO:0015701; GO:0004089; GO:0016021; GO:0046872; GO:0005886; GO:0044281,bicarbonate transport; carbonate dehydratase activity; integral to membrane; metal ion binding; plasma membrane; small molecule metabolic process,PF00194;,,,,,,,,,CAH14_HUMAN,Homo sapiens (Human),bicarbonate transport [GO:0015701] comp34804_c0_seq1,267,41.9476,0.26872035,7,6,,3.00E-12,Q9WTK3,Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1),Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1),GO:0034235; GO:0006506; GO:0003923; GO:0042765; GO:0005887,GPI anchor binding; GPI anchor biosynthetic process; GPI-anchor transamidase activity; GPI-anchor transamidase complex; integral to plasma membrane,PF04114;,,,,,,,,,GPAA1_MOUSE,Mus musculus (Mouse),attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506] comp34811_c0_seq1,297,45.7912,0.58014934,2,15,,7.00E-08,A9VFD6,Methylthioribose kinase (MTR kinase) (EC 2.7.1.100),Methylthioribose kinase (MTR kinase) (EC 2.7.1.100),GO:0005524; GO:0019284; GO:0019509; GO:0046522,ATP binding; L-methionine biosynthetic process from S-adenosylmethionine; L-methionine salvage from methylthioadenosine; S-methyl-5-thioribose kinase activity,PF01636;,,,,,,,,,MTNK_BACWK,Bacillus weihenstephanensis (strain KBAB4),L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284] comp34846_c0_seq1,231,50.2165,0.48406272,4,5,,2.00E-13,P0C090,Roquin-2 (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2),Roquin-2 (EC 6.3.2.-) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2),GO:0003677; GO:0003723; GO:0009986; GO:0000932; GO:0016020; GO:0008270,DNA binding; RNA binding; cell surface; cytoplasmic mRNA processing body; membrane; zinc ion binding,PF00642;PF13445;,,,,,,,,,RC3H2_MOUSE,Mus musculus (Mouse),B cell homeostasis [GO:0001782]; limb development [GO:0060173]; lung alveolus development [GO:0048286]; lymph node development [GO:0048535]; multicellular organism growth [GO:0035264]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-embryonic development [GO:0009791]; posttranscriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of gene expression [GO:0010468]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T follicular helper cell differentiation [GO:0061470] comp34872_c0_seq1,209,41.6268,1.11349315,4,4,,5.00E-07,Q8ZWC4,Putative ankyrin repeat protein PAE1861,Putative ankyrin repeat protein PAE1861,,,PF12796;,,,,,,,,,Y1861_PYRAE,Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827), comp34886_c0_seq1,233,40.7725,0.52846502,3,8,,5.00E-26,Q8K4Y7,Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog),Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog),GO:0032580; GO:0005509; GO:0005789; GO:0016021; GO:0043123; GO:0030166; GO:0004871; GO:0045134,Golgi cisterna membrane; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteoglycan biosynthetic process; signal transducer activity; uridine-diphosphatase activity,PF06079;,,,,,,,,,CANT1_RAT,Rattus norvegicus (Rat),positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166] comp34936_c0_seq1,426,44.1315,0.48878474,16,0,,4.00E-34,Q8IYI6,Exocyst complex component 8 (Exocyst complex 84 kDa subunit),Exocyst complex component 8 (Exocyst complex 84 kDa subunit),GO:0034613; GO:0044267; GO:0005737; GO:0000145; GO:0006887; GO:0030426; GO:0005634; GO:0005543; GO:0005886; GO:0015031,cellular protein localization; cellular protein metabolic process; cytoplasm; exocyst; exocytosis; growth cone; nucleus; phospholipid binding; plasma membrane; protein transport,PF16528;,2.00E-46,CHOYP_LOC100699161.1.1,,,,,,,EXOC8_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; exocyst assembly [GO:0001927]; exocyst localization [GO:0051601]; extracellular matrix disassembly [GO:0022617]; protein transport [GO:0015031]; regulation of macroautophagy [GO:0016241] comp34967_c0_seq1,300,41.6667,0.30919707,5,21,,9.00E-10,Q5ZM20,RecQ-mediated genome instability protein 2,RecQ-mediated genome instability protein 2,GO:0003677; GO:0006260; GO:0005737; GO:0005634,DNA binding; DNA replication; cytoplasm; nucleus,PF16100;,,,,,,,,,RMI2_CHICK,Gallus gallus (Chicken),DNA replication [GO:0006260] comp34979_c0_seq1,237,46.4135,0.73761644,7,5,,2.00E-21,Q58DA6,UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),GO:0000139; GO:0016021; GO:0005338; GO:0015780; GO:0005351,Golgi membrane; integral to membrane; nucleotide-sugar transmembrane transporter activity; nucleotide-sugar transport; sugar:hydrogen symporter activity,PF04142;,1.00E-14,CHOYP_LOC100703978.1.1,,,,,,,S35A2_BOVIN,Bos taurus (Bovine), comp34984_c0_seq1,224,33.4821,0.33333998,0,10,,4.00E-07,Q9JKN1,Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2),Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2),GO:0000139; GO:0008324; GO:0016023; GO:0016021; GO:0048471; GO:0032119; GO:0008270; GO:0006829,Golgi membrane; cation transmembrane transporter activity; cytoplasmic membrane-bounded vesicle; integral to membrane; perinuclear region of cytoplasm; sequestering of zinc ion; zinc ion binding; zinc ion transport,PF01545;,6.00E-11,CHOYP_BRAFLDRAFT_276675.1.1,,,,,,,ZNT7_MOUSE,Mus musculus (Mouse),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; zinc II ion transport [GO:0006829] comp35006_c0_seq1,251,41.8327,0.09389121,2,7,,1.00E-11,Q7PRB5,Protein OPI10 homolog,Protein OPI10 homolog,,,PF05603;,,,,,,,,,OPI10_ANOGA,Anopheles gambiae (African malaria mosquito), comp35018_c1_seq1,505,45.3465,0.46514661,6,9,,2.00E-27,Q96PE2,Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4),Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4),GO:0005089; GO:0030036; GO:0097190; GO:0005829; GO:0005085; GO:0048011; GO:0043065; GO:0035023; GO:0051056; GO:0007264,Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; apoptotic signaling pathway; cytosol; guanyl-nucleotide exchange factor activity; neurotrophin TRK receptor signaling pathway; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00621;,1.00E-43,CHOYP_LOC658611.1.1,,,,,,,ARHGH_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp35019_c0_seq1,225,45.3333,0.26725006,6,0,,4.00E-29,Q9DC53,Copine-8 (Copine VIII),Copine-8 (Copine VIII),,,PF00168;PF07002;,6.00E-30,CHOYP_CPNE8.2.2,,,,,,,CPNE8_MOUSE,Mus musculus (Mouse), comp35051_c0_seq1,289,43.2526,1.05073722,6,8,,5.00E-18,Q4I1Y5,Mannose-1-phosphate guanyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GTP-mannose-1-phosphate guanylyltransferase),Mannose-1-phosphate guanyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GTP-mannose-1-phosphate guanylyltransferase),GO:0009298; GO:0005525; GO:0007049; GO:0005737; GO:0004475,GDP-mannose biosynthetic process; GTP binding; cell cycle; cytoplasm; mannose-1-phosphate guanylyltransferase activity,PF00132;PF00483;,8.00E-24,CHOYP_NEMVEDRAFT_V1G162365.1.1,,,,,,,MPG1_GIBZE,Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum),cell cycle [GO:0007049]; cell wall mannoprotein biosynthetic process [GO:0000032]; fungal-type cell wall biogenesis [GO:0009272]; GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486] comp35086_c0_seq1,231,62.7706,0.97480818,0,9,,6.00E-22,P65336,4-alpha-glucanotransferase (EC 2.4.1.25) (Amylomaltase) (Disproportionating enzyme) (D-enzyme),,GO:0004134; GO:0005829,4-alpha-glucanotransferase activity; cytosol,,,,,,,,,,MALQ_MYCTU,, comp35096_c0_seq1,279,48.0287,0.77778777,7,1,,,,,,,,,3.00E-42,CHOYP_PUS3.1.1,,,,,,,,, comp35105_c0_seq1,218,36.2385,0.84885507,1,5,,1.00E-23,Q80U62,Run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon),Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon),GO:0005794; GO:0006914; GO:0005769; GO:0006897; GO:0005770; GO:0005764; GO:0010507; GO:0045806,Golgi apparatus; autophagy; early endosome; endocytosis; late endosome; lysosome; negative regulation of autophagy; negative regulation of endocytosis,PF02759;PF13901;,,,,,,,,,RUBIC_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; endocytosis [GO:0006897]; immune system process [GO:0002376]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553] comp35112_c1_seq1,322,37.8882,0.26104778,0,7,,3.00E-12,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp35132_c0_seq1,301,46.1794,0.20953053,7,0,,7.00E-19,C8YR32,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,1.00E-15,CHOYP_LOC100175334.1.2,,,,,,,LOXH1_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp35177_c0_seq1,281,44.8399,0.28535651,4,9,,3.00E-39,Q9CVD2,Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1 homolog),Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1 homolog),GO:0001012; GO:0034605; GO:0071218; GO:0035640; GO:0070932; GO:0006515; GO:0005759; GO:0031966; GO:0035520; GO:0042405; GO:0008242; GO:0043161; GO:0010810; GO:0006355; GO:0006351; GO:0004221; GO:0004843,"RNA polymerase II regulatory region DNA binding; cellular response to heat; cellular response to misfolded protein; exploration behavior; histone H3 deacetylation; misfolded or incompletely synthesized protein catabolic process; mitochondrial matrix; mitochondrial membrane; monoubiquitinated protein deubiquitination; nuclear inclusion body; omega peptidase activity; proteasomal ubiquitin-dependent protein catabolic process; regulation of cell-substrate adhesion; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-specific protease activity",PF02099;PF02809;,3.00E-28,CHOYP_BRAFLDRAFT_126822.1.1,,,,,,,ATX3_MOUSE,Mus musculus (Mouse),"actin cytoskeleton organization [GO:0030036]; cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; exploration behavior [GO:0035640]; histone H3 deacetylation [GO:0070932]; intermediate filament cytoskeleton organization [GO:0045104]; microtubule cytoskeleton organization [GO:0000226]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; monoubiquitinated protein deubiquitination [GO:0035520]; positive regulation of ERAD pathway [GO:1904294]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; regulation of cell-substrate adhesion [GO:0010810]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp35228_c0_seq1,265,34.717,0.53334093,9,0,,1.00E-15,Q8BWP8,"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)","Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)",GO:0000139; GO:0008532; GO:0007411; GO:0016021; GO:0030311; GO:0006486,"Golgi membrane; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; axon guidance; integral to membrane; poly-N-acetyllactosamine biosynthetic process; protein glycosylation",,,,,,,,,,B3GN1_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] comp3522_c0_seq1,424,42.9245,0.98958884,6,6,,1.00E-12,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp35237_c0_seq1,223,60.9865,0.97224177,0,7,,8.00E-14,Q9Z6S5,Ribonucleoside-diphosphate reductase subunit alpha (EC 1.17.4.1) (Ribonucleotide reductase),Ribonucleoside-diphosphate reductase subunit alpha (EC 1.17.4.1) (Ribonucleotide reductase),GO:0005524; GO:0006260; GO:0004748; GO:0005971,"ATP binding; DNA replication; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ribonucleoside-diphosphate reductase complex",PF03477;PF02867;PF00317;,,,,,,,,,RIR1_CHLPN,Chlamydia pneumoniae (Chlamydophila pneumoniae),DNA replication [GO:0006260] comp35260_c0_seq1,246,49.5935,0.47279972,10,0,,6.00E-29,Q9WTW1,Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2),Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2),GO:0030054; GO:0030425; GO:0043198; GO:0043197; GO:0005783; GO:0014069; GO:0045211; GO:0015031,cell junction; dendrite; dendritic shaft; dendritic spine; endoplasmic reticulum; postsynaptic density; postsynaptic membrane; protein transport,PF00595;,,,,,,,,,GRIP2_RAT,Rattus norvegicus (Rat),artery smooth muscle contraction [GO:0014824]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; protein transport [GO:0015031] comp35277_c0_seq1,340,47.6471,0.52365318,7,13,,3.00E-43,Q9Z272,ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1),ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1),GO:0008060; GO:0005737; GO:0005925; GO:0042803; GO:0032312; GO:0008277; GO:0031267; GO:0008270,ARF GTPase activator activity; cytoplasm; focal adhesion; protein homodimerization activity; regulation of ARF GTPase activity; regulation of G-protein coupled receptor protein signaling pathway; small GTPase binding; zinc ion binding,PF12796;PF01412;PF12205;PF16559;PF08518;,2.00E-57,CHOYP_GIT1.2.2,,,,,,,GIT1_RAT,Rattus norvegicus (Rat),dendritic spine development [GO:0060996]; immunological synapse formation [GO:0001771]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp35306_c0_seq1,218,49.0826,0.38530016,1,0,,1.00E-12,Q5SP46,Glucoside xylosyltransferase 1 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 3),Glucoside xylosyltransferase 1 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 3),GO:0016266; GO:0035252; GO:0016021,O-glycan processing; UDP-xylosyltransferase activity; integral to membrane,PF01501;,,,,,,,,,GXLT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),O-glycan processing [GO:0016266] comp3532_c0_seq1,277,48.0144,0.31576968,7,0,,1.00E-18,Q8N1W0,Transmembrane protein FLJ37396,,GO:0016021,integral to membrane,,1.00E-15,CHOYP_LOC579367.1.1,,,,,,,YF005_HUMAN,, comp35361_c0_seq1,248,57.2581,0.98869982,0,11,,1.00E-26,Q6A9J8,UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C),UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C),GO:0003677; GO:0009432; GO:0005737; GO:0009381; GO:0009380; GO:0006289,DNA binding; SOS response; cytoplasm; excinuclease ABC activity; excinuclease repair complex; nucleotide-excision repair,PF01541;PF02151;PF08459;,,,,,,,,,UVRC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432] comp35369_c0_seq1,314,45.5414,0.61620343,11,6,,2.00E-24,O57382,Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid),Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid),GO:0005509; GO:0030154; GO:0005576; GO:0004222; GO:0007275; GO:0006508; GO:0008270,calcium ion binding; cell differentiation; extracellular region; metalloendopeptidase activity; multicellular organismal development; proteolysis; zinc ion binding,PF01400;PF00431;PF00008;,6.00E-13,CHOYP_LOC591417.2.2,,,,,,,TLL2_XENLA,Xenopus laevis (African clawed frog),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp35372_c0_seq1,285,57.193,0.96326967,3,10,,2.00E-15,Q9KEE9,L-arabinose transport system permease protein AraQ,L-arabinose transport system permease protein AraQ,GO:0008643; GO:0016021; GO:0005886; GO:0005215,carbohydrate transport; integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,ARAQ_BACHD,Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125),carbohydrate transport [GO:0008643] comp35385_c0_seq1,244,65.1639,1.05369721,0,8,,5.00E-07,Q54F05,ATP-dependent RNA helicase dhx8 (EC 3.6.4.13) (DEAH box protein 8),ATP-dependent RNA helicase dhx8 (EC 3.6.4.13) (DEAH box protein 8),GO:0005524; GO:0004004; GO:0003723; GO:0008380; GO:0006397; GO:0005681,ATP binding; ATP-dependent RNA helicase activity; RNA binding; RNA splicing; mRNA processing; spliceosomal complex,PF00270;PF04408;PF00271;PF07717;PF00575;,,,,,,,,,DHX8_DICDI,Dictyostelium discoideum (Slime mold),"mRNA splicing, via spliceosome [GO:0000398]" comp35388_c0_seq1,204,49.0196,0.4928003,1,8,,1.00E-19,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp35393_c0_seq1,323,58.2043,0.95435377,0,17,,3.00E-15,Q83RZ7,Anaerobic dimethyl sulfoxide reductase chain B (DMSO reductase iron-sulfur subunit),Anaerobic dimethyl sulfoxide reductase chain B (DMSO reductase iron-sulfur subunit),GO:0051539; GO:0046872; GO:0055114,"4 iron, 4 sulfur cluster binding; metal ion binding; oxidation-reduction process",PF13247;PF12800;,,,,,,,,,DMSB_SHIFL,Shigella flexneri,oxidation-reduction process [GO:0055114] comp35442_c0_seq1,301,64.4518,1.12928597,1,15,,9.00E-12,P0A9W5,Uncharacterized ABC transporter ATP-binding protein YjjK,Energy-dependent translational throttle protein EttA (Translational regulatory factor EttA),GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;PF12848;,,,,,,,,,YJJK_SHIFL,Shigella flexneri,regulation of translation [GO:0006417]; translation [GO:0006412] comp35461_c0_seq1,430,49.3023,0.30962811,5,11,,5.00E-41,Q5PQY6,"Lon protease homolog 2, peroxisomal (EC 3.4.21.-)","Lon protease homolog 2, peroxisomal (EC 3.4.21.-)",GO:0005524; GO:0004176; GO:0006515; GO:0009295; GO:0005782; GO:0016558; GO:0016485; GO:0043565; GO:0004252,ATP binding; ATP-dependent peptidase activity; misfolded or incompletely synthesized protein catabolic process; nucleoid; peroxisomal matrix; protein import into peroxisome matrix; protein processing; sequence-specific DNA binding; serine-type endopeptidase activity,PF00004;PF05362;PF02190;,3.00E-62,CHOYP_BRAFLDRAFT_67608.1.2,,,,,,,LONP2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),misfolded or incompletely synthesized protein catabolic process [GO:0006515]; protein import into peroxisome matrix [GO:0016558]; protein processing [GO:0016485]; protein targeting to peroxisome [GO:0006625] comp35537_c0_seq1,673,42.3477,0.5339683,23,4,,2.00E-69,Q62904,3-keto-steroid reductase (EC 1.1.1.270) (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (PRL receptor-associated protein) (PRAP),3-keto-steroid reductase (EC 1.1.1.270) (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (PRL receptor-associated protein) (PRAP),GO:0000253; GO:0006695; GO:0005783; GO:0004303; GO:0006703; GO:0016021; GO:0005886; GO:0005148,3-keto sterol reductase activity; cholesterol biosynthetic process; endoplasmic reticulum; estradiol 17-beta-dehydrogenase activity; estrogen biosynthetic process; integral to membrane; plasma membrane; prolactin receptor binding,PF00106;,,,,,,,,,DHB7_RAT,Rattus norvegicus (Rat),estrogen biosynthetic process [GO:0006703]; hippocampus development [GO:0021766]; maternal process involved in female pregnancy [GO:0060135]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to organic cyclic compound [GO:0014070]; response to prolactin [GO:1990637] comp35551_c0_seq1,912,45.8333,0.36007467,26,69,,,,,,,,,2.00E-36,CHOYP_LOC662357.1.1,,,,,,,,, comp35552_c0_seq1,268,40.2985,0.37103965,0,19,,3.00E-12,Q52KB5,Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450),Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT24_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp35558_c0_seq1,561,49.3761,0.29719819,10,9,,4.00E-60,Q90XC2,Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8),Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8),GO:0005524; GO:0051301; GO:0005737; GO:0001947; GO:0046872; GO:0007067; GO:0072372; GO:0072116; GO:0004674; GO:0061326,ATP binding; cell division; cytoplasm; heart looping; metal ion binding; mitosis; primary cilium; pronephros formation; protein serine/threonine kinase activity; renal tubule development,PF00069;PF00415;,2.00E-41,CHOYP_LOC100375651.1.1,,,,,,,NEK8_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; mitotic nuclear division [GO:0007067]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326] comp35563_c0_seq1,235,42.5532,0.28331846,7,0,,,,,,,,,5.00E-25,CHOYP_RGD1561408.1.2,,,,,,,,, comp35575_c0_seq1,280,40,0.18396307,3,13,,1.00E-23,Q6DGX3,Ankyrin repeat domain-containing protein 54,Ankyrin repeat domain-containing protein 54,GO:0005737; GO:0030496; GO:0005634,cytoplasm; midbody; nucleus,PF00023;PF12796;,,,,,,,,,ANR54_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp35586_c0_seq1,226,46.4602,0.16485435,6,0,,3.00E-24,Q7Z4N2,Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1),Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1),GO:0007216; GO:0005262; GO:0060402; GO:0071482; GO:0005887; GO:0035841; GO:0046548; GO:0007601,G-protein coupled glutamate receptor signaling pathway; calcium channel activity; calcium ion transport into cytosol; cellular response to light stimulus; integral to plasma membrane; new growing cell tip; retinal rod cell development; visual perception,PF00520;PF16519;,1.00E-25,CHOYP_TRPM3.6.7,,,,,,,TRPM1_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cellular response to light stimulus [GO:0071482]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; protein tetramerization [GO:0051262]; retinal rod cell development [GO:0046548]; transport [GO:0006810]; visual perception [GO:0007601] comp35588_c0_seq1,226,61.9469,1.26009868,0,10,,6.00E-34,A1VM73,NADH-quinone oxidoreductase subunit N (EC 1.6.99.5) (NADH dehydrogenase I subunit N) (NDH-1 subunit N),NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N),GO:0042773; GO:0008137; GO:0016021; GO:0005886; GO:0048038; GO:0006810,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; integral to membrane; plasma membrane; quinone binding; transport,PF00361;,,,,,,,,,NUON_POLNA,Polaromonas naphthalenivorans (strain CJ2),ATP synthesis coupled electron transport [GO:0042773]; transport [GO:0006810] comp35602_c0_seq1,334,39.521,0.6923139,13,18,,3.00E-27,Q8BJL1,F-box only protein 30,F-box only protein 30 (Muscle ubiquitin ligase of SCF complex in atrophy-1) (MUSA1),GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,PF15966;PF15965;,,,,,,,,,FBX30_MOUSE,Mus musculus (Mouse), comp35624_c0_seq1,259,43.6293,0.49057335,1,13,,5.00E-09,Q9WU63,Heme-binding protein 2 (Protein SOUL),Heme-binding protein 2 (Protein SOUL),GO:0005737; GO:0005739,cytoplasm; mitochondrion,PF04832;,,,,,,,,,HEBP2_MOUSE,Mus musculus (Mouse),negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] comp35627_c0_seq1,274,44.8905,0.21883581,6,5,,5.00E-12,Q8MY86,Fibroblast growth factor receptor 1 (DjFgfr1) (FGFR-1) (EC 2.7.10.1) (DjPTK3),Fibroblast growth factor receptor 1 (DjFgfr1) (FGFR-1) (EC 2.7.10.1) (DjPTK3),GO:0005524; GO:0016021; GO:0018108; GO:0004714,ATP binding; integral to membrane; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity,PF07714;,,,,,,,,,FGFR1_DUGJA,Dugesia japonica (Planarian), comp35635_c0_seq1,240,42.9167,1.58801207,9,0,,2.00E-12,Q3UHR0,BAH and coiled-coil domain-containing protein 1,BAH and coiled-coil domain-containing protein 1,GO:0003677,DNA binding,PF01426;,4.00E-13,CHOYP_LOC100369237.2.3,,,,,,,BAHC1_MOUSE,Mus musculus (Mouse),chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507] comp35648_c0_seq1,202,45.0495,0.98070036,0,2,,3.00E-16,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,6.00E-17,CHOYP_LOC100533316.2.2,7.00E-14,ruditapes_c1110,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp35658_c0_seq1,205,56.0976,0.88359946,3,6,,7.00E-10,Q49729,Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205),Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205),GO:0006177; GO:0003938; GO:0030554; GO:0046872,GMP biosynthetic process; IMP dehydrogenase activity; adenyl nucleotide binding; metal ion binding,PF00571;PF00478;,,,,,,,,,IMDH_MYCLE,Mycobacterium leprae (strain TN),GMP biosynthetic process [GO:0006177] comp35691_c0_seq1,246,39.8374,1.24278783,0,8,,8.00E-07,Q6PCJ9,Lysosomal thioesterase PPT2-A (PPT-2-A) (EC 3.1.2.-),Lysosomal thioesterase PPT2-A (PPT-2-A) (EC 3.1.2.-),GO:0006464; GO:0005764; GO:0008474,cellular protein modification process; lysosome; palmitoyl-(protein) hydrolase activity,PF02089;,,,,,,,,,PPT2A_XENLA,Xenopus laevis (African clawed frog), comp35753_c0_seq1,212,59.9057,0.79836859,0,8,,2.00E-16,P46349,GABA permease (4-amino butyrate transport carrier) (Gamma-aminobutyrate permease),GABA permease (4-amino butyrate transport carrier) (Gamma-aminobutyrate permease) (Proline transporter GabP),GO:0009450; GO:0015185; GO:0016021; GO:0005886,gamma-aminobutyric acid catabolic process; gamma-aminobutyric acid transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,GABP_BACSU,Bacillus subtilis (strain 168),gamma-aminobutyric acid catabolic process [GO:0009450] comp35761_c0_seq1,338,42.8994,0.80174135,1,25,,,,,,,,,4.00E-28,CHOYP_LOC582121.1.1,,,,,,,,, comp35803_c0_seq1,536,63.0597,0.93391629,0,49,,9.00E-45,P29551,Elongation factor 3 (EF-3),Elongation factor 3 (EF-3),GO:0005524; GO:0006200; GO:0016887; GO:0003746,ATP binding; ATP catabolic process; ATPase activity; translation elongation factor activity,PF00005;,,,,,,,,,EF3_PNECA,Pneumocystis carinii, comp35869_c0_seq1,264,46.5909,0.56353812,5,4,,1.00E-14,Q2TAW0,Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2),Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2),GO:0051301; GO:0030261; GO:0007067; GO:0005634,cell division; chromosome condensation; mitosis; nucleus,PF12422;,,,,,,,,,CNDG2_XENLA,Xenopus laevis (African clawed frog),cell division [GO:0051301]; chromosome condensation [GO:0030261]; mitotic nuclear division [GO:0007067] comp35872_c0_seq1,306,45.7516,0.89505329,3,27,,4.00E-06,Q7M4T0,"Endo-1,6-beta-D-glucanase (EC 3.2.1.75) (Beta-1,6-glucanase Neg1) (Glucan endo-1,6-beta-glucosidase)","Endo-1,6-beta-D-glucanase (EC 3.2.1.75) (Beta-1,6-glucanase Neg1) (Glucan endo-1,6-beta-glucosidase)",GO:0005975; GO:0005576; GO:0046557; GO:0004348; GO:0006665,"carbohydrate metabolic process; extracellular region; glucan endo-1,6-beta-glucosidase activity; glucosylceramidase activity; sphingolipid metabolic process",PF02055;,,,,,,,,,NEG1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),carbohydrate metabolic process [GO:0005975]; sphingolipid metabolic process [GO:0006665] comp35899_c0_seq1,469,48.4009,0.43925433,9,11,,2.00E-82,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-98,CHOYP_DNAH5.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp35927_c0_seq1,357,36.9748,0.32874454,19,0,,2.00E-15,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp35947_c0_seq1,266,46.6165,0.27812893,8,0,,5.00E-21,Q5T011,Protein SZT2 (Seizure threshold 2 protein homolog),Protein SZT2 (Seizure threshold 2 protein homolog),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,2.00E-11,CHOYP_SZT2.1.1,,,,,,,SZT2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp35955_c0_seq1,223,43.9462,0.58410562,2,7,,3.00E-08,Q6IQ21,Zinc finger protein 770,Zinc finger protein 770,GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF13912;,,,,,,,,,ZN770_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp35996_c0_seq1,368,38.8587,0.88916319,8,28,,2.00E-08,Q9NRF2,"SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)","SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)",GO:0007596; GO:0006928; GO:0005829; GO:0035556; GO:0030032; GO:0016020; GO:0005634; GO:0005543; GO:0045840; GO:2000278; GO:0004871,blood coagulation; cellular component movement; cytosol; intracellular signal transduction; lamellipodium assembly; membrane; nucleus; phospholipid binding; positive regulation of mitosis; regulation of DNA biosynthetic process; signal transducer activity,PF00169;PF08916;PF00017;,,,,,,,,,SH2B1_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of DNA biosynthetic process [GO:2000278] comp36050_c0_seq1,202,31.6832,0.6000147,2,9,,,,,,,,,1.00E-18,CHOYP_LOC101237406.1.1,,,,,,,,, comp36059_c1_seq1,406,36.6995,0.47234329,9,6,,4.00E-08,Q20681,BTB and MATH domain-containing protein 38,BTB and MATH domain-containing protein 38,,,PF00651;PF00917;,,,,,,,,,BAT38_CAEEL,Caenorhabditis elegans, comp36084_c0_seq1,322,49.0683,0.53690677,6,8,,6.00E-20,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,,,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp36152_c0_seq1,366,48.0874,0.71235004,7,7,,4.00E-12,Q7TN83,Synaptotagmin-16 (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein),Synaptotagmin-16 (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein),GO:0016021; GO:0005543; GO:0042803,integral to membrane; phospholipid binding; protein homodimerization activity,PF00168;,2.00E-13,CHOYP_LOC100369472.2.2,,,,,,,SYT16_MOUSE,Mus musculus (Mouse),exocytosis [GO:0006887]; vesicle fusion [GO:0006906] comp36154_c0_seq1,240,44.1667,0.86910993,4,22,,5.00E-07,Q96T23,Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),GO:0034080; GO:0006352; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0005654; GO:0016584; GO:0045893; GO:0050434; GO:0008270,"CENP-A containing nucleosome assembly at centromere; DNA-dependent transcription, initiation; RSF complex; histone binding; negative regulation of DNA binding; negative regulation of transcription, DNA-dependent; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; positive regulation of viral transcription; zinc ion binding",PF00628;PF15612;,,,,,,,,,RSF1_HUMAN,Homo sapiens (Human),"CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]" comp36155_c0_seq1,209,61.244,0.66913297,0,12,,6.00E-10,P20707,2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase),2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase),GO:0006096; GO:0004591; GO:0030976; GO:0006099,glycolysis; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding; tricarboxylic acid cycle,PF16078;PF00676;PF16870;PF02779;,,,,,,,,,ODO1_AZOVI,Azotobacter vinelandii,glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] comp36188_c0_seq1,426,40.8451,0.73964432,1,0,,4.00E-34,A1ZAU8,Short spindle protein 4,Patronin (Short spindle protein 4),GO:0005813; GO:0005737; GO:0005874; GO:0051011; GO:0051013; GO:0030496; GO:0000022; GO:0007026; GO:0005819,centrosome; cytoplasm; microtubule; microtubule minus-end binding; microtubule severing; midbody; mitotic spindle elongation; negative regulation of microtubule depolymerization; spindle,PF17095;PF11971;PF08683;,2.00E-27,CHOYP_CPIPJ_CPIJ005871.1.1,,,,,,,SSP4_DROME,Drosophila melanogaster (Fruit fly),microtubule severing [GO:0051013]; mitotic spindle elongation [GO:0000022]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175] comp36288_c0_seq1,333,46.5465,0.61377099,2,10,,4.00E-28,O73590,Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) (Zinc finger/apterous-related homeobox protein),Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) (Zinc finger/apterous-related homeobox protein),GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;,4.00E-47,CHOYP_LOC100877335.1.1,,,,,,,ZFHX4_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp36289_c0_seq1,339,44.8378,0.61250758,5,18,,1.00E-14,O19010,Cysteine-rich secretory protein 3 (CRISP-3) (Acidic epididymal glycoprotein 2) (AEG2),Cysteine-rich secretory protein 3 (CRISP-3) (Acidic epididymal glycoprotein 2) (AEG2),GO:0016337; GO:0005576; GO:0009566; GO:0042581; GO:0007283,cell-cell adhesion; extracellular region; fertilization; specific granule; spermatogenesis,PF00188;PF08562;,,,,,,,,,CRIS3_HORSE,Equus caballus (Horse),fertilization [GO:0009566]; single organismal cell-cell adhesion [GO:0016337]; spermatogenesis [GO:0007283] comp36297_c0_seq1,307,42.0195,0.51827473,4,1,,9.00E-11,Q6NRK3,Ankyrin repeat domain-containing protein SOWAHB (Ankyrin repeat domain-containing protein 56) (Protein sosondowah homolog B),Ankyrin repeat domain-containing protein SOWAHB (Ankyrin repeat domain-containing protein 56) (Protein sosondowah homolog B),,,PF12796;,,,,,,,,,SWAHB_XENLA,Xenopus laevis (African clawed frog), comp36327_c0_seq1,258,43.7984,0.16928359,7,6,,6.00E-16,Q9Y2I7,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),GO:0000285; GO:0016308; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0045121; GO:0046872; GO:0032288; GO:0048471; GO:0043813; GO:0034504; GO:0042147; GO:0044281,"1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; membrane raft; metal ion binding; myelin assembly; perinuclear region of cytoplasm; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; protein localization to nucleus; retrograde transport, endosome to Golgi; small molecule metabolic process",PF00118;PF00610;PF01363;PF01504;,,,,,,,,,FYV1_HUMAN,Homo sapiens (Human),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp36370_c0_seq1,248,44.3548,0.49405565,0,5,,5.00E-11,O15943,Neural-cadherin (Cadherin-N) (dN-cadherin),Neural-cadherin (Cadherin-N) (dN-cadherin),GO:0045467; GO:0045463; GO:0030424; GO:0048846; GO:0007412; GO:0007413; GO:0008013; GO:0005509; GO:0016339; GO:0050839; GO:0044331; GO:0005911; GO:0030425; GO:0007156; GO:0005887; GO:0050774; GO:0016318; GO:0004872; GO:0048841; GO:0031290,R7 cell development; R8 cell development; axon; axon extension involved in axon guidance; axon target recognition; axonal fasciculation; beta-catenin binding; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell adhesion mediated by cadherin; cell-cell junction; dendrite; homophilic cell adhesion; integral to plasma membrane; negative regulation of dendrite morphogenesis; ommatidial rotation; receptor activity; regulation of axon extension involved in axon guidance; retinal ganglion cell axon guidance,PF00028;PF01049;PF00008;PF12661;PF02210;,,,,,,,,,CADN_DROME,Drosophila melanogaster (Fruit fly),axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233] comp36370_c1_seq1,202,49.0099,0.49756121,0,10,,5.00E-08,Q99PF4,Cadherin-23 (Otocadherin),Cadherin-23 (Otocadherin),GO:0060088; GO:0005509; GO:0016339; GO:0005929; GO:0007156; GO:0016021; GO:0007626; GO:0005932; GO:0001917; GO:0005886; GO:0048563; GO:0050953; GO:0007605; GO:0032420; GO:0032426; GO:0045202,auditory receptor cell stereocilium organization; calcium ion binding; calcium-dependent cell-cell adhesion; cilium; homophilic cell adhesion; integral to membrane; locomotory behavior; microtubule basal body; photoreceptor inner segment; plasma membrane; post-embryonic organ morphogenesis; sensory perception of light stimulus; sensory perception of sound; stereocilium; stereocilium bundle tip; synapse,PF00028;,,,,,,,,,CAD23_MOUSE,Mus musculus (Mouse),auditory receptor cell differentiation [GO:0042491]; auditory receptor cell stereocilium organization [GO:0060088]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; cell adhesion [GO:0007155]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] comp36378_c0_seq1,475,43.7895,0.81136723,5,5,,2.00E-21,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp36387_c0_seq1,218,36.2385,0.28628053,2,21,,2.00E-09,Q1EGL0,Leucine-rich repeat LGI family member 3 (Leucine-rich glioma-inactivated protein 3),Leucine-rich repeat LGI family member 3 (Leucine-rich glioma-inactivated protein 3),GO:0003824; GO:0030054; GO:0006887; GO:0005576; GO:0008152; GO:0043005; GO:0017157; GO:0008021,catalytic activity; cell junction; exocytosis; extracellular region; metabolic process; neuron projection; regulation of exocytosis; synaptic vesicle,PF03736;PF13855;,,,,,,,,,LGI3_PANTR,Pan troglodytes (Chimpanzee),exocytosis [GO:0006887]; regulation of exocytosis [GO:0017157] comp36396_c0_seq1,327,38.5321,1.08416981,17,0,,7.00E-13,Q9PW71,Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2),Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2),GO:0017017; GO:0001706; GO:0005654; GO:0035335; GO:0004725,MAP kinase tyrosine/serine/threonine phosphatase activity; endoderm formation; nucleoplasm; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00782;PF00581;,,,,,,,,,DUS4_CHICK,Gallus gallus (Chicken),dephosphorylation [GO:0016311]; endoderm formation [GO:0001706]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335] comp36397_c0_seq1,318,60.0629,1.21348258,0,11,,1.00E-21,P65064,Uncharacterized protein Mb3100c,Uncharacterized protein Mb3100c,,,PF04343;,,,,,,,,,Y3100_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp36413_c0_seq1,498,34.739,1.27057602,18,0,,,,,,,,,,,2.00E-38,ruditapes_c12922,,,,,,, comp36432_c0_seq1,207,61.3527,0.98164238,0,1,,4.00E-14,P0CQ76,ATP-dependent RNA helicase DBP2-A (EC 3.6.4.13),ATP-dependent RNA helicase DBP2-A (EC 3.6.4.13),GO:0005524; GO:0008026; GO:0003723; GO:0005737; GO:0000184; GO:0005634; GO:0006364,"ATP binding; ATP-dependent helicase activity; RNA binding; cytoplasm; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; rRNA processing",PF00270;PF00271;,,,,,,,,,DBP2_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]" comp36437_c0_seq1,210,46.1905,0.71831416,8,0,,3.00E-18,Q8K212,Phosphofurin acidic cluster sorting protein 1 (PACS-1),Phosphofurin acidic cluster sorting protein 1 (PACS-1),GO:0030137; GO:0000042; GO:0072661,COPI-coated vesicle; protein targeting to Golgi; protein targeting to plasma membrane,PF10254;,2.00E-11,CHOYP_BRAFLDRAFT_73177.1.1,,,,,,,PACS1_MOUSE,Mus musculus (Mouse),positive regulation of protein binding [GO:0032092]; protein targeting to Golgi [GO:0000042]; protein targeting to plasma membrane [GO:0072661] comp36445_c0_seq1,367,43.3243,0.35821161,14,19,,8.00E-42,Q09499,Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0030969; GO:0004521; GO:0030176; GO:0002119; GO:0004674,ATP binding; UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response; endoribonuclease activity; integral to endoplasmic reticulum membrane; nematode larval development; protein serine/threonine kinase activity,PF00069;PF01011;PF06479;,2.00E-46,CHOYP_BRAFLDRAFT_118819.2.2,,,,,,,IRE1_CAEEL,Caenorhabditis elegans,endoplasmic reticulum unfolded protein response [GO:0030968]; mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response [GO:0030969]; nematode larval development [GO:0002119]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein phosphorylation [GO:0006468]; response to hypoxia [GO:0001666]; response to topologically incorrect protein [GO:0035966]; response to tunicamycin [GO:1904576] comp36472_c0_seq1,829,42.4608,1.08582052,39,0,,2.00E-13,Q9PVY0,Retinal homeobox protein Rx1 (cRax1),Retinal homeobox protein Rx1 (cRax1),GO:0007275; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF03826;,6.00E-18,CHOYP_LOC100366437.1.1,,,,,,,RX1_CHICK,Gallus gallus (Chicken),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp3649_c0_seq1,227,50.2203,0.77793073,3,0,,5.00E-06,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp36546_c0_seq1,210,38.0952,0,0,8,,3.00E-07,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp36579_c0_seq1,247,41.7004,0.82256738,1,11,,9.00E-13,Q6NY73,Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B),Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B),GO:0007155; GO:0016020; GO:0005578; GO:0005044,cell adhesion; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00651;PF00530;,,,,,,,,,L3BPB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155] comp36583_c0_seq1,239,59.4142,1.19120608,0,18,,3.00E-06,P33642,Probable D-amino acid oxidase PA4548,Probable D-amino acid oxidase PA4548,GO:0050660; GO:0016491,flavin adenine dinucleotide binding; oxidoreductase activity,PF01266;,,,,,,,,,Y4548_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), comp36591_c0_seq1,232,40.0862,1.09289085,0,18,,,,,,,,,6.00E-11,CHOYP_PZRN4.1.1,,,,,,,,, comp36627_c0_seq1,262,46.1832,0.51082875,6,5,,9.00E-20,Q3UY23,Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1),Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1),GO:0005524; GO:0000287; GO:0004826; GO:0006432; GO:0000049; GO:0008033,ATP binding; magnesium ion binding; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding; tRNA processing,PF10354;PF03147;,,,,,,,,,FDXA1_MOUSE,Mus musculus (Mouse),rRNA base methylation [GO:0070475]; tRNA processing [GO:0008033] comp36628_c0_seq1,222,54.0541,0.62014606,1,12,,,,,,,,,,,1.00E-61,ruditapes2_lrc1763,,,,,,, comp36654_c0_seq1,230,45.6522,0.45366136,11,1,,6.00E-29,Q17QF0,"Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)","Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)",GO:0047305; GO:0008453; GO:0008152; GO:0005739; GO:0030170,(R)-3-amino-2-methylpropionate-pyruvate transaminase activity; alanine-glyoxylate transaminase activity; metabolic process; mitochondrion; pyridoxal phosphate binding,PF00202;,6.00E-11,CHOYP_TRIADDRAFT_63204.2.2,,,,,,,AGT2_BOVIN,Bos taurus (Bovine),"glyoxylate catabolic process [GO:0009436]; L-alanine catabolic process, by transamination [GO:0019481]; positive regulation of nitric oxide biosynthetic process [GO:0045429]" comp36691_c1_seq1,209,58.8517,0.98457852,0,11,,6.00E-09,P94390,Proline dehydrogenase 2 (PRODH 2) (EC 1.5.99.8) (Proline oxidase 2),Proline dehydrogenase 2 (PRODH 2) (EC 1.5.5.2) (Proline oxidase 2),GO:0006537; GO:0010133; GO:0004657,glutamate biosynthetic process; proline catabolic process to glutamate; proline dehydrogenase activity,PF01619;,,,,,,,,,PROD2_BACSU,Bacillus subtilis (strain 168),proline catabolic process to glutamate [GO:0010133] comp36735_c0_seq1,285,47.7193,0.43531738,6,0,,2.00E-08,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,2.00E-17,CHOYP_LOC580670.1.6,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp36742_c0_seq1,255,40.7843,0.75768831,8,4,,2.00E-07,Q03601,RING finger protein nhl-1,RING finger protein nhl-1,GO:0008270,zinc ion binding,PF01436;PF00097;,,,,,,,,,NHL1_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567] comp36781_c0_seq1,203,59.6059,0.83608586,0,8,,3.00E-22,P0A4Z8,Aspartokinase (EC 2.7.2.4) (Aspartate kinase) (ASK),,GO:0005524; GO:0016597; GO:0004072; GO:0005618; GO:0019877; GO:0040007; GO:0009089; GO:0005886; GO:0009088,ATP binding; amino acid binding; aspartate kinase activity; cell wall; diaminopimelate biosynthetic process; growth; lysine biosynthetic process via diaminopimelate; plasma membrane; threonine biosynthetic process,,,,,,,,,,AK_MYCTU,, comp36803_c0_seq1,205,62.9268,1.0449524,0,2,,2.00E-08,P0A5J3,Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M),Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M),GO:0004177; GO:0009987; GO:0046872; GO:0008235; GO:0006508,aminopeptidase activity; cellular process; metal ion binding; metalloexopeptidase activity; proteolysis,PF00557;,,,,,,,,,AMPM_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),protein initiator methionine removal [GO:0070084] comp36806_c0_seq1,254,41.7323,0.63569361,3,9,,,,,,,,,,,2.00E-21,ruditapes_c31873,,,,,,, comp36816_c0_seq1,446,35.8744,0.4926808,8,29,,6.00E-41,P51523,Zinc finger protein 84 (Zinc finger protein HPF2),Zinc finger protein 84 (Zinc finger protein HPF2),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZNF84_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp36823_c0_seq1,213,42.723,0.31196023,0,11,,2.00E-07,Q04202,Transposable element Tcb2 transposase,Transposable element Tcb2 transposase,GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,3.00E-21,CHOYP_LOC100207270.3.3,,,,,,,TCB2_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp36858_c0_seq1,214,71.028,0.96848962,0,7,,5.00E-34,A1TSA3,Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT),Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT),GO:0006564; GO:0004648; GO:0005737; GO:0030170; GO:0008615,L-serine biosynthetic process; O-phospho-L-serine:2-oxoglutarate aminotransferase activity; cytoplasm; pyridoxal phosphate binding; pyridoxine biosynthetic process,PF00266;,,,,,,,,,SERC_ACIAC,Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli),L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615] comp36865_c0_seq1,558,41.5771,0.48524461,9,60,,1.00E-75,P13234,Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR) (Calspermin),Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR) (Calspermin),GO:0005524; GO:0004683; GO:0005829; GO:0006954; GO:0007616; GO:0043011; GO:0005730; GO:0005654; GO:0045893,"ATP binding; calmodulin-dependent protein kinase activity; cytosol; inflammatory response; long-term memory; myeloid dendritic cell differentiation; nucleolus; nucleoplasm; positive regulation of transcription, DNA-dependent",PF00069;,3.00E-51,CHOYP_CAMK4.1.1,,,,,,,KCC4_RAT,Rattus norvegicus (Rat),"adaptive immune response [GO:0002250]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; myeloid dendritic cell differentiation [GO:0043011]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]" comp3686_c1_seq1,315,43.1746,0.35088073,7,0,,,,,,,,,7.00E-12,CHOYP_BRAFLDRAFT_80394.5.9,,,,,,,,, comp36912_c0_seq1,206,44.6602,0.58947758,1,6,,3.00E-15,Q8BS35,Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195),Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195),GO:0005783; GO:0005789; GO:0046485; GO:0006633; GO:0050479; GO:0016021; GO:0005506; GO:0006643,endoplasmic reticulum; endoplasmic reticulum membrane; ether lipid metabolic process; fatty acid biosynthetic process; glyceryl-ether monooxygenase activity; integral to membrane; iron ion binding; membrane lipid metabolic process,PF04116;,,,,,,,,,ALKMO_MOUSE,Mus musculus (Mouse),ether lipid metabolic process [GO:0046485]; fatty acid biosynthetic process [GO:0006633]; membrane lipid metabolic process [GO:0006643] comp36913_c0_seq1,311,45.3376,0.56727859,6,6,,5.00E-26,Q9NYU2,UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1),UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1),GO:0051084; GO:0003980; GO:0005788; GO:0005793; GO:0043687; GO:0018279; GO:0051082,'de novo' posttranslational protein folding; UDP-glucose:glycoprotein glucosyltransferase activity; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; post-translational protein modification; protein N-linked glycosylation via asparagine; unfolded protein binding,PF06427;,,,,,,,,,UGGG1_HUMAN,Homo sapiens (Human),'de novo' posttranslational protein folding [GO:0051084]; endoplasmic reticulum mannose trimming [GO:1904380]; protein glycosylation [GO:0006486] comp36927_c0_seq1,217,38.2488,0.64422172,3,0,,5.00E-10,O14746,Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2),Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2),GO:0022616; GO:0016605; GO:0003723; GO:0006278; GO:0003964; GO:0005737; GO:0046872; GO:2001240; GO:0000783; GO:0005730; GO:0005654; GO:0042803; GO:0090399; GO:0005697; GO:0032203; GO:0007004; GO:0042162; GO:0070034; GO:0003721,DNA strand elongation; PML body; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; cytoplasm; metal ion binding; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; nuclear telomere cap complex; nucleolus; nucleoplasm; protein homodimerization activity; replicative senescence; telomerase holoenzyme complex; telomere formation via telomerase; telomere maintenance via telomerase; telomeric DNA binding; telomeric RNA binding; telomeric template RNA reverse transcriptase activity,PF00078;PF12009;,,,,,,,,,TERT_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; cellular response to hypoxia [GO:0071456]; DNA biosynthetic process [GO:0071897]; DNA strand elongation [GO:0022616]; establishment of protein localization to telomere [GO:0070200]; mitochondrion organization [GO:0007005]; negative regulation of cellular senescence [GO:2000773]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of production of siRNA involved in RNA interference [GO:1903704]; positive regulation of hair cycle [GO:0042635]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of Wnt signaling pathway [GO:0030177]; production of siRNA involved in RNA interference [GO:0030422]; regulation of protein stability [GO:0031647]; replicative senescence [GO:0090399]; RNA biosynthetic process [GO:0032774]; RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; transcription, RNA-templated [GO:0001172]" comp36951_c0_seq1,454,44.0529,1.2844099,21,0,,5.00E-17,Q5F3G7,"Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)","Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)",GO:0016266; GO:0001525; GO:0016263; GO:0016021; GO:0001822; GO:0046872,O-glycan processing; angiogenesis; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; integral to membrane; kidney development; metal ion binding,PF02434;,,,,,,,,,C1GLT_CHICK,Gallus gallus (Chicken),"angiogenesis [GO:0001525]; intestinal epithelial cell development [GO:0060576]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]" comp36961_c0_seq1,437,44.8513,0.59343719,19,0,,2.00E-35,Q9ESR9,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0016887; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0005765; GO:0005815; GO:0032383; GO:0006357; GO:0048545; GO:0006810,ATP binding; ATPase activity; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lysosomal membrane; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to steroid hormone stimulus; transport,PF00005;,,,,,,,,,ABCA2_RAT,Rattus norvegicus (Rat),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp37007_c0_seq1,234,31.1966,0.53008487,2,4,,6.00E-06,A1YPR0,Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C),Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C),GO:0046872; GO:0003676,metal ion binding; nucleic acid binding,PF00651;,,,,,,,,,ZBT7C_HUMAN,Homo sapiens (Human),positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025] comp37065_c0_seq1,242,61.5702,1.18860725,2,2,,7.00E-25,P0A620,DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme),,GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0005618; GO:0005829; GO:0040007; GO:0000287; GO:0060701; GO:0005886,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; cell wall; cytosol; growth; magnesium ion binding; negative regulation of ribonuclease activity; plasma membrane,,,,,,,,,,TOP1_MYCTU,, comp37090_c0_seq1,273,46.1538,0.42724066,3,5,,5.00E-39,Q9P2S5,WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),GO:0005813; GO:0005737,centrosome; cytoplasm,PF12894;,1.00E-32,CHOYP_LOC100368359.2.2,,,,,,,WRP73_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp37161_c0_seq1,218,72.4771,1.26328568,0,12,,4.00E-09,P0ADP4,Uncharacterized protein YigI,Uncharacterized protein YigI,,,PF03061;,,,,,,,,,YIGI_SHIFL,Shigella flexneri, comp37178_c0_seq1,280,44.6429,0.43231321,13,0,,3.00E-31,Q810J8,Zinc finger FYVE domain-containing protein 1,Zinc finger FYVE domain-containing protein 1,GO:0005545; GO:0005795; GO:0005783; GO:0046872; GO:0010923; GO:0048471; GO:0005547; GO:0043325,"1-phosphatidylinositol binding; Golgi stack; endoplasmic reticulum; metal ion binding; negative regulation of phosphatase activity; perinuclear region of cytoplasm; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding",PF01363;,,,,,,,,,ZFYV1_MOUSE,Mus musculus (Mouse),cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923] comp37189_c0_seq1,305,40,0.76692554,6,3,,1.00E-15,Q96K62,Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499),Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT45_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp37189_c1_seq1,340,45,0.52444063,16,13,,2.00E-12,P0CG31,Putative zinc finger protein 286B,Putative zinc finger protein 286B,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13465;,,,,,,,,,Z286B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp37191_c0_seq1,243,55.9671,1.0080623,0,10,,4.00E-14,O58969,Uncharacterized ABC transporter extracellular-binding protein PH1214,Uncharacterized ABC transporter extracellular-binding protein PH1214,GO:0005886; GO:0005215,plasma membrane; transporter activity,PF01547;,,,,,,,,,Y1214_PYRHO,Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3), comp37223_c0_seq1,259,44.7876,0.54103066,9,20,,6.00E-09,P71667,Carboxylesterase NlhH (EC 3.1.1.1),,GO:0004091; GO:0009056; GO:0034338,carboxylesterase activity; catabolic process; short-chain carboxylesterase activity,,,,,,,,,,NLHH_MYCTU,, comp37248_c0_seq1,327,42.5076,0.33968835,9,4,,2.00E-23,Q5R9A7,Integral membrane protein GPR155,Integral membrane protein GPR155,GO:0016021; GO:0035556; GO:0055085,integral to membrane; intracellular signal transduction; transmembrane transport,PF00610;PF03547;,,,,,,,,,GP155_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] comp37280_c0_seq1,204,70.5882,1.14704666,0,12,,4.00E-20,P27830,"dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46)","dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46)",GO:0009243; GO:0050662; GO:0008460; GO:0019305; GO:0045226; GO:0009103,"O antigen biosynthetic process; coenzyme binding; dTDP-glucose 4,6-dehydratase activity; dTDP-rhamnose biosynthetic process; extracellular polysaccharide biosynthetic process; lipopolysaccharide biosynthetic process",PF16363;,,,,,,,,,RMLB2_ECOLI,Escherichia coli (strain K12),enterobacterial common antigen biosynthetic process [GO:0009246]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; nucleotide-sugar metabolic process [GO:0009225] comp37319_c0_seq1,282,44.6809,0.71592097,0,19,,1.00E-07,Q58461,Uncharacterized membrane protein MJ1061,Uncharacterized membrane protein MJ1061,GO:0009058,biosynthetic process,PF02719;,,,,,,,,,Y1061_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii), comp37364_c0_seq1,289,35.6401,0.4393992,0,12,,3.00E-06,Q6IR37,Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 24) (DHHC-24),Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 24) (DHHC-24),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDH24_MOUSE,Mus musculus (Mouse), comp37370_c0_seq1,201,57.7114,1.3214719,0,5,,3.00E-22,Q6A8B4,50S ribosomal protein L31,50S ribosomal protein L31,GO:0046872; GO:0019843; GO:0005840; GO:0003735; GO:0006412,metal ion binding; rRNA binding; ribosome; structural constituent of ribosome; translation,PF01197;,,,,,,,,,RL31_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),translation [GO:0006412] comp37379_c0_seq1,365,40.274,0.47798866,11,6,,1.00E-36,Q06190,Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B),Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B),GO:0090244; GO:0005509; GO:0001754; GO:0090090; GO:0090263; GO:0045732; GO:0006470; GO:0000159; GO:0008601; GO:0090249; GO:0007525; GO:0061053,Wnt receptor signaling pathway involved in somitogenesis; calcium ion binding; eye photoreceptor cell differentiation; negative regulation of canonical Wnt receptor signaling pathway; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein catabolic process; protein dephosphorylation; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; regulation of cell motility involved in somitogenic axis elongation; somatic muscle development; somite development,PF13499;,,,,,,,,,P2R3A_HUMAN,Homo sapiens (Human),eye photoreceptor cell differentiation [GO:0001754]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein catabolic process [GO:0045732]; protein dephosphorylation [GO:0006470]; regulation of cell motility involved in somitogenic axis elongation [GO:0090249]; somatic muscle development [GO:0007525]; somite development [GO:0061053]; Wnt signaling pathway involved in somitogenesis [GO:0090244] comp37389_c0_seq1,239,42.6778,0.47981648,0,9,,3.00E-07,Q8RH03,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ_FUSNN,Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp37395_c0_seq1,227,74.0088,1.03535428,0,11,,1.00E-13,Q72V65,Probable spermidine synthase (EC 2.5.1.16) (Putrescine aminopropyltransferase) (PAPT) (SPDSY),Polyamine aminopropyltransferase (Putrescine aminopropyltransferase) (PAPT) (Spermidine synthase) (SPDS) (SPDSY) (EC 2.5.1.16),GO:0008295; GO:0004766,spermidine biosynthetic process; spermidine synthase activity,,,,,,,,,,SPEE_LEPIC,Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130),spermidine biosynthetic process [GO:0008295] comp37430_c0_seq1,233,44.206,0.55715312,9,0,,4.00E-19,P31650,Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11),Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11),GO:0007420; GO:0042995; GO:0005737; GO:0005332; GO:0005887; GO:0042165; GO:0005328; GO:0042493,brain development; cell projection; cytoplasm; gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter binding; neurotransmitter:sodium symporter activity; response to drug,PF00209;,,,,,,,,,S6A11_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836]; response to drug [GO:0042493] comp37470_c0_seq1,241,39.0041,0.98598348,0,8,,1.00E-19,Q9VLC0,Vacuolar protein sorting-associated protein 54 (Protein scattered),Vacuolar protein sorting-associated protein 54 (Protein scattered),GO:0005794; GO:0006896; GO:0005739; GO:0015031; GO:0042147; GO:0007291,"Golgi apparatus; Golgi to vacuole transport; mitochondrion; protein transport; retrograde transport, endosome to Golgi; sperm individualization",PF07928;PF10475;,,,,,,,,,VPS54_DROME,Drosophila melanogaster (Fruit fly),"endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]" comp37481_c0_seq1,495,40,0.77694553,13,5,,5.00E-50,Q9N0Z4,Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (RING finger-binding protein) (Fragment),Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) (RING finger-binding protein) (Fragment),GO:0005524; GO:0019829; GO:0005769; GO:0005783; GO:0016021; GO:0000287; GO:0005637; GO:0004012; GO:0055038,ATP binding; cation-transporting ATPase activity; early endosome; endoplasmic reticulum; integral to membrane; magnesium ion binding; nuclear inner membrane; phospholipid-translocating ATPase activity; recycling endosome membrane,PF00122;PF16212;PF16209;,9.00E-39,CHOYP_LOC101173537.1.1,,,,,,,AT11B_RABIT,Oryctolagus cuniculus (Rabbit), comp37496_c0_seq1,271,73.0627,1.19446071,0,8,,7.00E-11,P27303,Multidrug resistance protein A,Multidrug export protein EmrA,GO:0009276; GO:0015238; GO:0016021; GO:0031237; GO:0046677,"Gram-negative-bacterium-type cell wall; drug transmembrane transporter activity; integral to membrane; intrinsic to external side of plasma membrane, in periplasmic space; response to antibiotic",PF00529;PF16576;,,,,,,,,,EMRA_ECOLI,Escherichia coli (strain K12),response to antibiotic [GO:0046677] comp37511_c0_seq1,246,48.7805,0.70998586,6,0,,2.00E-20,P27867,Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase),Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase),GO:0003939; GO:0042802; GO:0031966; GO:0031514; GO:0046686; GO:0046688; GO:0042493; GO:0009725; GO:0031667; GO:0006970; GO:0030317; GO:0008270,L-iditol 2-dehydrogenase activity; identical protein binding; mitochondrial membrane; motile cilium; response to cadmium ion; response to copper ion; response to drug; response to hormone stimulus; response to nutrient levels; response to osmotic stress; sperm motility; zinc ion binding,PF08240;PF00107;,4.00E-26,CHOYP_DHSO.2.2,2.00E-35,ruditapes_c17614,,,,,DHSO_RAT,Rattus norvegicus (Rat),fructose biosynthetic process [GO:0046370]; L-xylitol catabolic process [GO:0051160]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]; sperm motility [GO:0030317] comp37555_c0_seq1,1058,35.7278,1.49302262,26,66,,2.00E-18,Q8C119,Protein NDNF (Epidermacan) (Neuron-derived neurotrophic factor),Protein NDNF (Epidermacan) (Neuron-derived neurotrophic factor),GO:0016049; GO:0031012; GO:0030198; GO:0005576; GO:0008201; GO:0043524; GO:0001764; GO:0019800; GO:0010811; GO:0010976,cell growth; extracellular matrix; extracellular matrix organization; extracellular region; heparin binding; negative regulation of neuron apoptotic process; neuron migration; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; positive regulation of cell-substrate adhesion; positive regulation of neuron projection development,PF10179;,,,,,,,,,NDNF_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; nitric oxide mediated signal transduction [GO:0007263]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of neuron projection development [GO:0010976]; response to ischemia [GO:0002931]; vascular wound healing [GO:0061042] comp37568_c0_seq1,430,48.6047,0.39469078,12,0,,1.00E-06,Q02357,Ankyrin-1 (ANK-1) (Erythrocyte ankyrin),Ankyrin-1 (ANK-1) (Erythrocyte ankyrin),GO:0030863; GO:0048821; GO:0016020; GO:0015672; GO:0006779; GO:0016529; GO:0007165; GO:0014731,cortical cytoskeleton; erythrocyte development; membrane; monovalent inorganic cation transport; porphyrin-containing compound biosynthetic process; sarcoplasmic reticulum; signal transduction; spectrin-associated cytoskeleton,PF12796;PF00531;PF00791;,1.00E-42,CHOYP_TRIADDRAFT_51756.1.1,,,,,,,ANK1_MOUSE,Mus musculus (Mouse),ER to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; iron ion homeostasis [GO:0055072]; monovalent inorganic cation transport [GO:0015672]; porphyrin-containing compound biosynthetic process [GO:0006779]; protein targeting to plasma membrane [GO:0072661]; signal transduction [GO:0007165] comp37568_c1_seq1,283,47.3498,0.56990678,3,8,,4.00E-06,Q7T2B9,Myotrophin,Myotrophin,GO:0005634; GO:0048471,nucleus; perinuclear region of cytoplasm,PF12796;,,,,,,,,,MTPN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp37602_c0_seq1,274,33.9416,0.63599367,3,32,,5.00E-13,O95479,GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)],GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)],GO:0017057; GO:0050661; GO:0030246; GO:0005788; GO:0047936; GO:0004345; GO:0005739; GO:0006098; GO:0097305,6-phosphogluconolactonase activity; NADP binding; carbohydrate binding; endoplasmic reticulum lumen; glucose 1-dehydrogenase [NAD(P)] activity; glucose-6-phosphate dehydrogenase activity; mitochondrion; pentose-phosphate shunt; response to alcohol,PF02781;PF00479;PF01182;,,,,,,,,,G6PE_HUMAN,Homo sapiens (Human),glucose metabolic process [GO:0006006]; pentose-phosphate shunt [GO:0006098] comp37627_c0_seq1,461,46.4208,0.57213892,6,11,,5.00E-13,Q92581,Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6),Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6),GO:0031901; GO:0005789; GO:0016021; GO:0005886; GO:0055038; GO:0006885; GO:0015385,early endosome membrane; endoplasmic reticulum membrane; integral to membrane; plasma membrane; recycling endosome membrane; regulation of pH; sodium:hydrogen antiporter activity,PF00999;,3.00E-25,CHOYP_SL9A7.2.2,,,,,,,SL9A6_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; dendrite extension [GO:0097484]; dendritic spine development [GO:0060996]; ion transport [GO:0006811]; neuron projection morphogenesis [GO:0048812]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386]; sodium ion import across plasma membrane [GO:0098719]; synapse organization [GO:0050808]; transport [GO:0006810] comp37683_c0_seq1,577,45.234,0.61135452,2,73,,2.00E-10,Q8R508,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT3_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp37690_c0_seq1,260,30,0.3452432,3,5,,,,,,,,,,,2.00E-16,ruditapes_c11534,,,,,,, comp37749_c0_seq1,285,45.614,0.5546735,13,0,,8.00E-26,Q9NZL6,Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1),Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1),GO:0008321; GO:0044255; GO:0005829; GO:0051056; GO:0007264; GO:0044281,Ral guanyl-nucleotide exchange factor activity; cellular lipid metabolic process; cytosol; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; small molecule metabolic process,PF00788;PF00617;PF00618;,6.00E-38,CHOYP_LOC655842.1.1,,,,,,,RGL1_HUMAN,Homo sapiens (Human),small GTPase mediated signal transduction [GO:0007264] comp37749_c1_seq1,377,44.8276,0.68843297,9,5,,2.00E-20,Q60695,Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1),Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1),GO:0005085; GO:0005622; GO:0051056; GO:0007264,guanyl-nucleotide exchange factor activity; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00788;PF00617;PF00618;,,,,,,,,,RGL1_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp37769_c0_seq1,220,48.6364,0.71754729,3,5,,2.00E-27,Q5EAJ7,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp37772_c0_seq1,295,41.3559,0.87598531,4,10,,1.00E-18,Q7ZU45,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,,,,,,,,,,TTC25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp37792_c0_seq1,424,43.8679,0.29537984,12,22,,1.00E-14,Q505K2,Protein FAM160A1,Protein FAM160A1,,,PF10257;,1.00E-16,CHOYP_F16A2.3.3,,,,,,,F16A1_MOUSE,Mus musculus (Mouse), comp37851_c0_seq1,436,38.9908,0.72833716,8,9,,8.00E-38,O88529,Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1),Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1),GO:0003677; GO:0032922; GO:0005737; GO:0005634; GO:0006355; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"DNA binding; circadian regulation of gene expression; cytoplasm; nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;PF00989;,3.00E-18,CHOYP_BMAL1.1.1,,,,,,,BMAL1_MESAU,Mesocricetus auratus (Golden hamster),"circadian regulation of gene expression [GO:0032922]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp37910_c0_seq1,288,45.1389,0.55564236,2,24,,1.00E-39,Q921E2,Ras-related protein Rab-31,Ras-related protein Rab-31,GO:0019003; GO:0005525; GO:0005794; GO:0043001; GO:0032869; GO:0005769; GO:0045335; GO:0030670; GO:0090382; GO:0031623; GO:0045055; GO:0007264; GO:0032588,GDP binding; GTP binding; Golgi apparatus; Golgi to plasma membrane protein transport; cellular response to insulin stimulus; early endosome; phagocytic vesicle; phagocytic vesicle membrane; phagosome maturation; receptor internalization; regulated secretory pathway; small GTPase mediated signal transduction; trans-Golgi network membrane,PF00071;,4.00E-34,CHOYP_LOC585164.1.1,,,,,,,RAB31_MOUSE,Mus musculus (Mouse),cellular response to insulin stimulus [GO:0032869]; Golgi to plasma membrane protein transport [GO:0043001]; phagosome maturation [GO:0090382]; receptor internalization [GO:0031623]; regulated exocytosis [GO:0045055]; small GTPase mediated signal transduction [GO:0007264] comp37911_c0_seq1,463,41.0367,0.66286024,13,3,,5.00E-12,B0S5N4,Plexin A3,Plexin A3,GO:0048675; GO:0048755; GO:0060272; GO:0016021; GO:0005622; GO:0008045; GO:0005886; GO:0004872; GO:0048696; GO:0007165,axon extension; branching morphogenesis of a nerve; embryonic skeletal joint morphogenesis; integral to membrane; intracellular; motor neuron axon guidance; plasma membrane; receptor activity; regulation of collateral sprouting in absence of injury; signal transduction,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp37912_c0_seq1,220,42.7273,0.30695079,11,0,,5.00E-16,Q96BY7,Autophagy-related protein 2 homolog B,Autophagy-related protein 2 homolog B,GO:0006914; GO:0005811; GO:0034045,autophagy; lipid particle; pre-autophagosomal structure membrane,PF13329;PF09333;PF12624;,,,,,,,,,ATG2B_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp3794_c0_seq1,320,40.3125,0.15440266,5,0,,2.00E-29,Q8BJ51,UNC93-like protein MFSD11 (Major facilitator superfamily domain-containing protein 11) (Protein ET),UNC93-like protein MFSD11 (Major facilitator superfamily domain-containing protein 11) (Protein ET),GO:0016021,integral to membrane,PF05978;,2.00E-45,CHOYP_LOC100369212.1.1,,,,,,,MFS11_MOUSE,Mus musculus (Mouse), comp37974_c0_seq1,319,47.0219,0.81396149,10,6,,5.00E-19,O14512,"Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)","Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)",GO:0017124; GO:0005737; GO:0045444; GO:0008286; GO:0035556; GO:0009968; GO:0005634; GO:0005886; GO:0016567; GO:0040008,SH3 domain binding; cytoplasm; fat cell differentiation; insulin receptor signaling pathway; intracellular signal transduction; negative regulation of signal transduction; nucleus; plasma membrane; protein ubiquitination; regulation of growth,PF00017;PF07525;,2.00E-26,CHOYP_LOC588073.1.1,,,,,,,SOCS7_HUMAN,Homo sapiens (Human),cytokine-mediated signaling pathway [GO:0019221]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; layer formation in cerebral cortex [GO:0021819]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; protein ubiquitination [GO:0016567]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of growth [GO:0040008] comp38061_c0_seq1,326,29.7546,0.16925625,1,7,,4.00E-07,P75261,UPF0134 protein MPN_137,UPF0134 protein MPN_137,,,PF01519;,,,,,,,,,Y137_MYCPN,Mycoplasma pneumoniae (strain ATCC 29342 / M129), comp3808_c0_seq1,267,44.9438,0.52242448,4,0,,7.00E-14,P98161,Polycystin-1 (Autosomal dominant polycystic kidney disease 1 protein),Polycystin-1 (Autosomal dominant polycystic kidney disease 1 protein),GO:0007259; GO:0016323; GO:0048754; GO:0005262; GO:0007161; GO:0030246; GO:0001502; GO:0051216; GO:0007050; GO:0005737; GO:0042994; GO:0050982; GO:0048565; GO:0001892; GO:0048806; GO:0007507; GO:0007156; GO:0005887; GO:0001889; GO:0060428; GO:0072177; GO:0072218; GO:0072205; GO:0072287; GO:0072237; GO:0031512; GO:0021915; GO:0007218; GO:0006807; GO:0005634; GO:0018105; GO:0060674; GO:0002133; GO:0031659; GO:0032092; GO:0045944; GO:0006611; GO:0060236; GO:0043588; GO:0021510,JAK-STAT cascade; basolateral plasma membrane; branching morphogenesis of an epithelial tube; calcium channel activity; calcium-independent cell-matrix adhesion; carbohydrate binding; cartilage condensation; cartilage development; cell cycle arrest; cytoplasm; cytoplasmic sequestering of transcription factor; detection of mechanical stimulus; digestive tract development; embryonic placenta development; genitalia development; heart development; homophilic cell adhesion; integral to plasma membrane; liver development; lung epithelium development; mesonephric duct development; metanephric ascending thin limb development; metanephric collecting duct development; metanephric distal tubule morphogenesis; metanephric proximal tubule development; motile primary cilium; neural tube development; neuropeptide signaling pathway; nitrogen compound metabolic process; nucleus; peptidyl-serine phosphorylation; placenta blood vessel development; polycystin complex; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of protein binding; positive regulation of transcription from RNA polymerase II promoter; protein export from nucleus; regulation of mitotic spindle organization; skin development; spinal cord development,PF00059;PF13855;PF00801;PF08016;PF01477;PF02010;PF01822;,,,,,,,,,PKD1_HUMAN,Homo sapiens (Human),anatomical structure morphogenesis [GO:0009653]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-independent cell-matrix adhesion [GO:0007161]; calcium ion transmembrane transport [GO:0070588]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; digestive tract development [GO:0048565]; embryonic placenta development [GO:0001892]; establishment of cell polarity [GO:0030010]; genitalia development [GO:0048806]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; JAK-STAT cascade [GO:0007259]; kidney development [GO:0001822]; liver development [GO:0001889]; lung epithelium development [GO:0060428]; lymph vessel morphogenesis [GO:0036303]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric collecting duct development [GO:0072205]; metanephric distal tubule morphogenesis [GO:0072287]; metanephric proximal tubule development [GO:0072237]; neural tube development [GO:0021915]; nitrogen compound metabolic process [GO:0006807]; peptidyl-serine phosphorylation [GO:0018105]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein export from nucleus [GO:0006611]; regulation of cell adhesion [GO:0030155]; regulation of mitotic spindle organization [GO:0060236]; regulation of proteasomal protein catabolic process [GO:0061136]; response to fluid shear stress [GO:0034405]; single organismal cell-cell adhesion [GO:0016337]; skin development [GO:0043588]; spinal cord development [GO:0021510] comp38090_c0_seq1,523,41.4914,0.17835327,18,6,,4.00E-41,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,1.00E-43,CHOYP_UBR3.1.1,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp38132_c0_seq1,247,67.2065,1.00858589,0,7,,2.00E-09,P0AG37,Homoserine/homoserine lactone efflux protein,Homoserine/homoserine lactone efflux protein,GO:0006865; GO:0016021; GO:0005886,amino acid transport; integral to membrane; plasma membrane,PF01810;,,,,,,,,,RHTB_SHIFL,Shigella flexneri,amino acid transport [GO:0006865] comp38192_c0_seq1,513,43.6647,0.25237412,12,16,,2.00E-16,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,,,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp38195_c0_seq1,224,42.4107,0.50314062,4,20,,8.00E-30,Q9NVH2,Integrator complex subunit 7 (Int7),Integrator complex subunit 7 (Int7),GO:0000077; GO:0071479; GO:0005694; GO:0032039; GO:0016180,DNA damage checkpoint; cellular response to ionizing radiation; chromosome; integrator complex; snRNA processing,,1.00E-38,CHOYP_INT7.1.1,,,,,,,INT7_HUMAN,Homo sapiens (Human),cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint [GO:0000077]; snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp38207_c0_seq1,234,61.5385,1.13528643,0,10,,4.00E-06,P46731,18 kDa antigen 2 (Clone MAVC83),18 kDa antigen 2 (Clone MAVC83),,,PF00011;,,,,,,,,,18K2_MYCAV,Mycobacterium avium, comp38230_c0_seq1,324,37.037,0.54182233,4,20,,6.00E-07,Q4P6L3,Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),GO:0000139; GO:0031901; GO:0016021; GO:0016746; GO:0008270,"Golgi membrane; early endosome membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,2.00E-13,CHOYP_LOC764485.2.2,,,,,,,AKR1_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus), comp38243_c0_seq1,310,40,0.41533552,10,0,,3.00E-27,Q6ZT07,TBC1 domain family member 9 (TBC1 domain family member 9A),TBC1 domain family member 9 (TBC1 domain family member 9A),GO:0005097; GO:0005509; GO:0032851,Rab GTPase activator activity; calcium ion binding; positive regulation of Rab GTPase activity,PF02893;PF00566;,1.00E-33,CHOYP_BRAFLDRAFT_153908.2.2,,,,,,,TBCD9_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp38245_c0_seq1,212,69.3396,1.26459214,0,15,,1.00E-31,Q8XWM7,L-aspartate oxidase 1 (LASPO 1) (EC 1.4.3.16) (Quinolinate synthase B 1),L-aspartate oxidase 1 (LASPO 1) (EC 1.4.3.16) (Quinolinate synthase B 1),GO:0008734; GO:0044318; GO:0009435; GO:0005737,L-aspartate oxidase activity; L-aspartate:fumarate oxidoreductase activity; NAD biosynthetic process; cytoplasm,PF00890;PF02910;,,,,,,,,,NADB1_RALSO,Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum),NAD biosynthetic process [GO:0009435] comp38275_c0_seq1,212,60.8491,0.92165512,0,6,,2.00E-08,Q42698,"Geranylgeranyl pyrophosphate synthase, chloroplastic (GGPP synthase) (GGPS) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranyltranstransferase) (EC 2.5.1.10)","Geranylgeranyl pyrophosphate synthase, chloroplastic (GGPP synthase) (GGPS) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranyltranstransferase) (EC 2.5.1.10)",GO:0016117; GO:0009507; GO:0004161; GO:0045337; GO:0004311; GO:0033384; GO:0033386; GO:0004337; GO:0046872,carotenoid biosynthetic process; chloroplast; dimethylallyltranstransferase activity; farnesyl diphosphate biosynthetic process; farnesyltranstransferase activity; geranyl diphosphate biosynthetic process; geranylgeranyl diphosphate biosynthetic process; geranyltranstransferase activity; metal ion binding,PF00348;,,,,,,,,,GGPPS_CATRO,Catharanthus roseus (Madagascar periwinkle) (Vinca rosea),carotenoid biosynthetic process [GO:0016117]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386] comp38306_c0_seq1,257,40.856,0.38710264,1,3,,1.00E-08,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp38315_c0_seq1,716,48.743,0.37726988,13,0,,8.00E-15,Q99PW8,Kinesin-like protein KIF17 (MmKIF17),Kinesin-like protein KIF17 (MmKIF17),GO:0005524; GO:0036064; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007017; GO:0031503; GO:0015031; GO:0016192,ATP binding; cilium basal body; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; microtubule-based process; protein complex localization; protein transport; vesicle-mediated transport,PF00225;,,,,,,,,,KIF17_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neurogenesis [GO:0022008]; protein complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] comp38315_c0_seq2,535,46.9159,0.44297675,4,0,,2.00E-14,Q6RT24,Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10),Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10),GO:0005524; GO:0008608; GO:0051301; GO:0000940; GO:0000778; GO:0005737; GO:0045184; GO:0005871; GO:0043515; GO:0003777; GO:0007018; GO:0007080; GO:0007094; GO:0007275; GO:0051987; GO:0045842; GO:0045860; GO:0050793; GO:0051233,ATP binding; attachment of spindle microtubules to kinetochore; cell division; condensed chromosome outer kinetochore; condensed nuclear chromosome kinetochore; cytoplasm; establishment of protein localization; kinesin complex; kinetochore binding; microtubule motor activity; microtubule-based movement; mitotic metaphase plate congression; mitotic spindle assembly checkpoint; multicellular organismal development; positive regulation of attachment of spindle microtubules to kinetochore; positive regulation of mitotic metaphase/anaphase transition; positive regulation of protein kinase activity; regulation of developmental process; spindle midzone,PF00225;,,,,,,,,,CENPE_MOUSE,Mus musculus (Mouse),attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; establishment of protein localization [GO:0045184]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint [GO:0007094]; multicellular organism development [GO:0007275]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein kinase activity [GO:0045860]; regulation of developmental process [GO:0050793]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic nuclear division [GO:0007088] comp38330_c0_seq1,214,46.2617,0.26391738,0,5,,7.00E-25,Q66K14,TBC1 domain family member 9B,TBC1 domain family member 9B,GO:0005097; GO:0005509; GO:0016021; GO:0032851,Rab GTPase activator activity; calcium ion binding; integral to membrane; positive regulation of Rab GTPase activity,PF02893;PF00566;,3.00E-15,CHOYP_BRAFLDRAFT_153908.2.2,,,,,,,TBC9B_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp38334_c0_seq1,279,59.4982,0.94153256,0,20,,3.00E-24,P29767,Sialidase (EC 3.2.1.18) (Neuraminidase),Sialidase (EC 3.2.1.18) (Neuraminidase),GO:0005975; GO:0007155; GO:0052794; GO:0052795; GO:0052796; GO:0005576,carbohydrate metabolic process; cell adhesion; exo-alpha-(2->3)-sialidase activity; exo-alpha-(2->6)-sialidase activity; exo-alpha-(2->8)-sialidase activity; extracellular region,PF13088;PF00754;PF02973;,,,,,,,,,NANH_CLOSE,Clostridium septicum,carbohydrate metabolic process [GO:0005975] comp38340_c0_seq1,223,55.6054,0.7265011,0,12,,6.00E-30,Q6A9Q5,Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP-MurNAc-pentapeptide phosphotransferase),Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP-MurNAc-pentapeptide phosphotransferase),GO:0051992; GO:0007049; GO:0051301; GO:0016021; GO:0009252; GO:0008963; GO:0005886; GO:0008360,"UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity; cell cycle; cell division; integral to membrane; peptidoglycan biosynthetic process; phospho-N-acetylmuramoyl-pentapeptide-transferase activity; plasma membrane; regulation of cell shape",PF00953;PF10555;,,,,,,,,,MRAY_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp38343_c0_seq1,255,60.3922,1.1858134,0,8,,2.00E-20,Q6ABX9,Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2),Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2),GO:0004742; GO:0006096,dihydrolipoyllysine-residue acetyltransferase activity; glycolysis,PF00198;PF00364;PF02817;,,,,,,,,,ODP2_LEIXX,Leifsonia xyli subsp. xyli (strain CTCB07),glycolytic process [GO:0006096] comp38350_c0_seq1,341,48.6804,0.4990558,6,6,,2.00E-12,A8DYE2,Transient receptor potential cation channel trpm,"Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)",GO:0005261; GO:0034703; GO:0016049; GO:0070838; GO:0010960; GO:0046873; GO:0007005; GO:0055069,cation channel activity; cation channel complex; cell growth; divalent metal ion transport; magnesium ion homeostasis; metal ion transmembrane transporter activity; mitochondrion organization; zinc ion homeostasis,PF00520;PF16519;,,,,,,,,,TRPCG_DROME,Drosophila melanogaster (Fruit fly),cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069] comp38355_c0_seq1,201,44.7761,0.40401,1,4,,8.00E-10,A8MPX8,Protein phosphatase 2C-like domain-containing protein 1,Protein phosphatase 2C-like domain-containing protein 1,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF00481;,,,,,,,,,PP2D1_HUMAN,Homo sapiens (Human), comp38359_c0_seq1,237,40.9283,0.62196229,4,0,,6.00E-10,Q5RBE1,Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1),Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1),GO:0005525; GO:0006184; GO:0003924; GO:0000139; GO:0051607; GO:0005576,GTP binding; GTP catabolic process; GTPase activity; Golgi membrane; defense response to virus; extracellular region,PF02263;PF02841;,,,,,,,,,GBP1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),defense response to virus [GO:0051607] comp38364_c0_seq1,327,36.6972,0.91111963,4,3,,2.00E-13,Q6XQG9,"Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2)","Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2)",GO:0032580; GO:0009058; GO:0001733; GO:0016021,Golgi cisterna membrane; biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane,PF06990;,,,,,,,,,G3ST2_PIG,Sus scrofa (Pig),glycolipid biosynthetic process [GO:0009247] comp38406_c0_seq1,317,46.3722,0.76527974,11,0,,,,,,,,,1.00E-33,CHOYP_LOC100369720.1.1,,,,,,,,, comp38427_c0_seq1,207,63.285,0.7464289,0,6,,9.00E-17,Q9SDM1,"Chlorophyll a-b binding protein 1B-21, chloroplastic (LHCI type I CAB-1B-21) (LHCI-730 chlorophyll a/b binding protein) (Light-harvesting complex I 21 kDa protein)","Chlorophyll a-b binding protein 1B-21, chloroplastic (LHCI type I CAB-1B-21) (LHCI-730 chlorophyll a/b binding protein) (Light-harvesting complex I 21 kDa protein)",GO:0016168; GO:0009535; GO:0016021; GO:0046872; GO:0009765; GO:0009522; GO:0009523; GO:0018298,"chlorophyll binding; chloroplast thylakoid membrane; integral to membrane; metal ion binding; photosynthesis, light harvesting; photosystem I; photosystem II; protein-chromophore linkage",PF00504;,,,,,,,,,CB121_HORVU,Hordeum vulgare (Barley),"photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]" comp38464_c0_seq1,269,37.5465,0.34615863,5,6,,1.00E-14,Q6DFV5,Probable helicase with zinc finger domain (EC 3.6.4.-),Probable helicase with zinc finger domain (EC 3.6.4.-),GO:0005524; GO:0004386; GO:0046872; GO:0005634,ATP binding; helicase activity; metal ion binding; nucleus,PF00642;,,,,,,,,,HELZ_MOUSE,Mus musculus (Mouse), comp38471_c0_seq1,278,46.4029,0.60390392,2,12,,3.00E-07,Q5U580,Kelch domain-containing protein 10,Kelch domain-containing protein 10,GO:0005737; GO:0005634,cytoplasm; nucleus,PF01344;,,,,,,,,,KLD10_XENLA,Xenopus laevis (African clawed frog), comp38498_c0_seq1,242,60.3306,1.33468188,2,12,,1.00E-39,Q6A7J9,Uridylate kinase (UK) (EC 2.7.4.22) (Uridine monophosphate kinase) (UMP kinase) (UMPK),Uridylate kinase (UK) (EC 2.7.4.22) (Uridine monophosphate kinase) (UMP kinase) (UMPK),GO:0044210; GO:0005524; GO:0033862; GO:0005737,'de novo' CTP biosynthetic process; ATP binding; UMP kinase activity; cytoplasm,PF00696;,,,,,,,,,PYRH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' CTP biosynthetic process [GO:0044210] comp38499_c0_seq1,238,46.2185,0.403587,8,3,,4.00E-27,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,3.00E-27,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp38561_c0_seq1,300,45.6667,0.32089909,12,0,,7.00E-18,Q9H9Y6,DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135),GO:0003677; GO:0005736; GO:0003899; GO:0005737; GO:0009790; GO:0007566; GO:0046872; GO:0017126; GO:0005654; GO:0009303; GO:0032549; GO:0006363; GO:0006362; GO:0006361,DNA binding; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase activity; cytoplasm; embryo development; embryo implantation; metal ion binding; nucleologenesis; nucleoplasm; rRNA transcription; ribonucleoside binding; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter,PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;,,,,,,,,,RPA2_HUMAN,Homo sapiens (Human),"embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]" comp38567_c0_seq1,277,46.5704,0.5590822,2,5,,3.00E-40,Q6DFH5,SH3 domain-containing YSC84-like protein 1,SH3 domain-containing YSC84-like protein 1,,,PF00018;PF04366;,,,,,,,,,SH3Y1_XENLA,Xenopus laevis (African clawed frog), comp38574_c0_seq2,426,41.784,1.11416139,4,38,,3.00E-16,Q9NFT7,Hexokinase type 2 (EC 2.7.1.1),Hexokinase type 2 (EC 2.7.1.1),GO:0005524; GO:0001678; GO:0005829; GO:0008865; GO:0004340; GO:0006096; GO:0019158,ATP binding; cellular glucose homeostasis; cytosol; fructokinase activity; glucokinase activity; glycolysis; mannokinase activity,PF00349;PF03727;,,,,,,,,,HXK2_DROME,Drosophila melanogaster (Fruit fly),cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013] comp38589_c0_seq1,265,47.5472,1.11269558,9,5,,6.00E-16,Q9UEW3,Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2),Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2),GO:0043277; GO:0007166; GO:0005581; GO:0030666; GO:0045087; GO:0005887; GO:0005044; GO:0008329; GO:0004888,apoptotic cell clearance; cell surface receptor signaling pathway; collagen; endocytic vesicle membrane; innate immune response; integral to plasma membrane; scavenger receptor activity; signaling pattern recognition receptor activity; transmembrane signaling receptor activity,PF01391;PF00530;,,,,,,,,,MARCO_HUMAN,Homo sapiens (Human),apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898] comp38689_c0_seq1,252,43.254,1.02916875,10,6,,3.00E-24,P26433,Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3),Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3),GO:0030165; GO:0016324; GO:0031526; GO:0007623; GO:0016021; GO:0006898; GO:0006885; GO:0002028; GO:0051384; GO:0015385,PDZ domain binding; apical plasma membrane; brush border membrane; circadian rhythm; integral to membrane; receptor-mediated endocytosis; regulation of pH; regulation of sodium ion transport; response to glucocorticoid stimulus; sodium:hydrogen antiporter activity,PF00999;,2.00E-31,CHOYP_AAEL_AAEL001503.1.1,,,,,,,SL9A3_RAT,Rattus norvegicus (Rat),circadian rhythm [GO:0007623]; receptor-mediated endocytosis [GO:0006898]; regulation of pH [GO:0006885]; regulation of sodium ion transport [GO:0002028]; response to glucocorticoid [GO:0051384]; sodium ion transport [GO:0006814] comp38734_c0_seq1,432,43.287,0.46827937,10,13,,2.00E-11,P87319,Vacuolar protein sorting-associated protein 13a,Vacuolar protein sorting-associated protein 13a,GO:0005794; GO:0005829; GO:0005768; GO:0006886; GO:0045324; GO:0045053,Golgi apparatus; cytosol; endosome; intracellular protein transport; late endosome to vacuole transport; protein retention in Golgi apparatus,PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13A_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; vesicle-mediated transport [GO:0016192] comp38766_c0_seq1,215,48.8372,0.31579631,1,15,,1.00E-35,Q963B7,60S ribosomal protein L9,60S ribosomal protein L9,GO:0019843; GO:0005840; GO:0003735; GO:0006412,rRNA binding; ribosome; structural constituent of ribosome; translation,PF00347;,1.00E-77,CHOYP_RL9.5.6,2.00E-40,ruditapes_lrc34996,,,,,RL9_SPOFR,Spodoptera frugiperda (Fall armyworm),translation [GO:0006412] comp38855_c0_seq1,321,46.729,0.36207248,7,7,,4.00E-32,Q812E4,Synaptotagmin-like protein 5,Synaptotagmin-like protein 5,GO:0006886; GO:0016020; GO:0046872,intracellular protein transport; membrane; metal ion binding,PF00168;PF02318;,3.00E-36,CHOYP_SYTL5.1.1,,,,,,,SYTL5_RAT,Rattus norvegicus (Rat),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; intracellular protein transport [GO:0006886]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906] comp38863_c0_seq1,212,68.8679,1.00228091,0,9,,6.00E-06,P02942,Methyl-accepting chemotaxis protein I (MCP-I) (Serine chemoreceptor protein),Methyl-accepting chemotaxis protein I (MCP-I) (Serine chemoreceptor protein),GO:0048870; GO:0006935; GO:0016021; GO:0005886; GO:0007165; GO:0004888,cell motility; chemotaxis; integral to membrane; plasma membrane; signal transduction; transmembrane signaling receptor activity,PF00672;PF00015;PF02203;,,,,,,,,,MCP1_ECOLI,Escherichia coli (strain K12),cell motility [GO:0048870]; chemotaxis [GO:0006935]; response to amino acid [GO:0043200]; signal transduction [GO:0007165] comp38877_c0_seq1,247,45.749,0.24140564,7,5,,2.00E-07,Q9UBN7,Histone deacetylase 6 (HD6) (EC 3.5.1.98),Histone deacetylase 6 (HD6) (EC 3.5.1.98),GO:0070846; GO:0051879; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016235; GO:0070842; GO:0043014; GO:0005901; GO:0031252; GO:0070301; GO:0071218; GO:0035967; GO:0005881; GO:0005829; GO:0070840; GO:0019899; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0032418; GO:0016236; GO:0005874; GO:0005875; GO:0008017; GO:0006515; GO:0010727; GO:0007026; GO:0051354; GO:0043242; GO:0045861; GO:0045892; GO:0034983; GO:0048471; GO:0031593; GO:0070845; GO:0090035; GO:0010634; GO:1901300; GO:0010870; GO:0009967; GO:0043241; GO:0000209; GO:0060765; GO:0070201; GO:0060632; GO:0010469; GO:0070848; GO:0051788; GO:0009636; GO:0048156; GO:0006351; GO:0042903; GO:0043162; GO:0008270,"Hsp90 deacetylation; Hsp90 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); aggresome; aggresome assembly; alpha-tubulin binding; caveola; cell leading edge; cellular response to hydrogen peroxide; cellular response to misfolded protein; cellular response to topologically incorrect protein; cytoplasmic microtubule; cytosol; dynein complex binding; enzyme binding; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; lysosome localization; macroautophagy; microtubule; microtubule associated complex; microtubule binding; misfolded or incompletely synthesized protein catabolic process; negative regulation of hydrogen peroxide metabolic process; negative regulation of microtubule depolymerization; negative regulation of oxidoreductase activity; negative regulation of protein complex disassembly; negative regulation of proteolysis; negative regulation of transcription, DNA-dependent; peptidyl-lysine deacetylation; perinuclear region of cytoplasm; polyubiquitin binding; polyubiquitinated misfolded protein transport; positive regulation of chaperone-mediated protein complex assembly; positive regulation of epithelial cell migration; positive regulation of hydrogen peroxide-mediated programmed cell death; positive regulation of receptor biosynthetic process; positive regulation of signal transduction; protein complex disassembly; protein polyubiquitination; regulation of androgen receptor signaling pathway; regulation of establishment of protein localization; regulation of microtubule-based movement; regulation of receptor activity; response to growth factor stimulus; response to misfolded protein; response to toxic substance; tau protein binding; transcription, DNA-dependent; tubulin deacetylase activity; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; zinc ion binding",PF00850;PF02148;,,,,,,,,,HDAC6_HUMAN,Homo sapiens (Human),"aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; organelle organization [GO:0006996]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of microtubule-based movement [GO:0060632]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]" comp3895_c0_seq1,236,38.1356,0.9595314,2,0,,4.00E-08,Q27274,60 kDa SS-A/Ro ribonucleoprotein homolog,60 kDa SS-A/Ro ribonucleoprotein homolog,GO:0003723; GO:0005737; GO:0046872; GO:0030529,RNA binding; cytoplasm; metal ion binding; ribonucleoprotein complex,PF05731;,,,,,,,,,RO60_CAEEL,Caenorhabditis elegans, comp38998_c0_seq1,212,69.8113,1.01300955,0,10,,2.00E-14,Q55CV9,CaiB/baiF CoA-transferase family protein DDB_G0269880 (EC 2.-.-.-),CaiB/baiF CoA-transferase family protein DDB_G0269880 (EC 2.-.-.-),GO:0016740,transferase activity,PF02515;,,,,,,,,,Y9880_DICDI,Dictyostelium discoideum (Slime mold), comp39136_c0_seq1,414,48.0676,0.71566658,7,14,,2.00E-29,P31732,Muscle cell intermediate filament protein OV71 (Fragment),Muscle cell intermediate filament protein OV71 (Fragment),GO:0005882; GO:0005198,intermediate filament; structural molecule activity,PF00038;,2.00E-45,CHOYP_NF70.4.4,,,,,,,OV71_ONCVO,Onchocerca volvulus, comp39190_c0_seq1,242,69.4215,0.93316911,0,11,,9.00E-11,A1JTG3,Pesticin receptor (IPR65) (IRPC),Pesticin receptor (IPR65) (IRPC),GO:0009279; GO:0016021; GO:0005506; GO:0004872; GO:0044718; GO:0015343,cell outer membrane; integral to membrane; iron ion binding; receptor activity; siderophore transmembrane transport; siderophore transmembrane transporter activity,PF07715;PF00593;,,,,,,,,,FYUA_YERE8,Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; siderophore transport [GO:0015891] comp39206_c0_seq1,210,36.1905,0.87735877,3,5,,6.00E-11,P98074,Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain],Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain],GO:0016021; GO:0006508; GO:0005044; GO:0004252,integral to membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00431;PF00057;PF00629;PF01390;PF00530;PF00089;,,,,,,,,,ENTK_PIG,Sus scrofa (Pig), comp39218_c0_seq1,260,40.3846,0.37964198,8,9,,9.00E-34,Q8VDS4,Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein),Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein),GO:0016591; GO:0070940,"DNA-directed RNA polymerase II, holoenzyme; dephosphorylation of RNA polymerase II C-terminal domain",PF16566;PF04818;,7.00E-30,CHOYP_LOC100181755.1.1,,,,,,,RPR1A_MOUSE,Mus musculus (Mouse),dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940] comp39224_c0_seq1,292,40.0685,0.8638073,2,14,,1.00E-17,P12791,Cytochrome P450 2B10 (EC 1.14.14.1) (CYPIIB10) (CYPIIB20) (Cytochrome P450 2B20) (Cytochrome P450 clone PF3/46) (Cytochrome P450-16-alpha) (P24) (Testosterone 16-alpha hydroxylase),Cytochrome P450 2B10 (EC 1.14.14.1) (CYPIIB10) (CYPIIB20) (Cytochrome P450 2B20) (Cytochrome P450 clone PF3/46) (Cytochrome P450-16-alpha) (P24) (Testosterone 16-alpha hydroxylase),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2BA_MOUSE,Mus musculus (Mouse),cellular ketone metabolic process [GO:0042180]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805] comp39247_c0_seq1,280,47.8571,0.81668826,3,16,,2.00E-19,Q80V23,Zinc finger protein 32 (Zinc finger protein 637),Zinc finger protein 32 (Zinc finger protein 637),GO:0046872; GO:0003676; GO:0005634,metal ion binding; nucleic acid binding; nucleus,PF00096;,,,,,,,,,ZNF32_MOUSE,Mus musculus (Mouse), comp39283_c0_seq1,227,47.1366,0.33703537,3,11,,1.00E-23,Q8WND5,Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein),Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein),GO:0033588; GO:0005737; GO:0008607; GO:0030335; GO:0006357; GO:0008023; GO:0006351,"Elongator holoenzyme complex; cytoplasm; phosphorylase kinase regulator activity; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; transcription elongation factor complex; transcription, DNA-dependent",PF04762;,4.00E-13,CHOYP_ELP1.2.2,,,,,,,ELP1_RABIT,Oryctolagus cuniculus (Rabbit),"positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]" comp39293_c0_seq1,210,45.7143,0.73392969,5,0,,2.00E-17,Q9P2K8,Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein),eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein),GO:0005524; GO:0009267; GO:0022626; GO:0030968; GO:0004694; GO:0017148; GO:0006446; GO:0043558,ATP binding; cellular response to starvation; cytosolic ribosome; endoplasmic reticulum unfolded protein response; eukaryotic translation initiation factor 2alpha kinase activity; negative regulation of translation; regulation of translational initiation; regulation of translational initiation in response to stress,PF12745;PF00069;PF05773;,,,,,,,,,E2AK4_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; cell cycle arrest [GO:0007050]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; induction by virus of host autophagy [GO:0039520]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] comp39305_c0_seq1,392,60.4592,1.1548957,2,7,,7.00E-89,Q6A6A3,Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase),GO:0044208; GO:0005525; GO:0004019; GO:0005737; GO:0000287,'de novo' AMP biosynthetic process; GTP binding; adenylosuccinate synthase activity; cytoplasm; magnesium ion binding,PF00709;,,,,,,,,,PURA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' AMP biosynthetic process [GO:0044208] comp39309_c0_seq1,644,31.2112,0.76953854,663,0,,1.00E-09,Q96M34,Uncharacterized protein C3orf30,Uncharacterized protein C3orf30,,,,,,,,,,,,CC030_HUMAN,Homo sapiens (Human), comp39336_c0_seq1,210,57.1429,1.23223039,1,7,,2.00E-14,A0QUX7,Acetolactate synthase small subunit (EC 2.2.1.6) (Acetohydroxy-acid synthase small subunit) (AHAS) (ALS),Acetolactate synthase small subunit (EC 2.2.1.6) (Acetohydroxy-acid synthase small subunit) (AHAS) (ALS),GO:0003984; GO:0009097; GO:0009099,acetolactate synthase activity; isoleucine biosynthetic process; valine biosynthetic process,PF10369;,,,,,,,,,ILVH_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] comp39387_c0_seq1,202,48.5149,0.59185124,0,10,,2.00E-06,O70145,Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox),Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox),GO:0006742; GO:0001669; GO:0007568; GO:0032870; GO:0005829; GO:0016020; GO:0005730; GO:0045777; GO:0043525; GO:0014823; GO:0042493; GO:0009749; GO:0055093; GO:0034616; GO:0032496; GO:0032570; GO:0042554,NADP catabolic process; acrosomal vesicle; aging; cellular response to hormone stimulus; cytosol; membrane; nucleolus; positive regulation of blood pressure; positive regulation of neuron apoptotic process; response to activity; response to drug; response to glucose stimulus; response to hyperoxia; response to laminar fluid shear stress; response to lipopolysaccharide; response to progesterone stimulus; superoxide anion generation,PF00564;PF00018;PF00515;PF13181;,,,,,,,,,NCF2_MOUSE,Mus musculus (Mouse),NADP catabolic process [GO:0006742]; oxidation-reduction process [GO:0055114]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] comp39461_c0_seq1,236,38.5593,1.14605539,3,7,,2.00E-12,Q8C0R9,Leucine-rich repeat and death domain-containing protein 1,Leucine-rich repeat and death domain-containing protein 1,,,PF13855;,,,,,,,,,LRRD1_MOUSE,Mus musculus (Mouse), comp39504_c0_seq1,353,38.5269,0.38353504,10,0,,2.00E-30,Q8BJ90,Zinc finger protein 771,Zinc finger protein 771,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN771_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp39511_c0_seq1,220,49.0909,1.0364572,4,0,,7.00E-21,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp39511_c1_seq1,202,48.5149,0.7875193,4,0,,3.00E-06,Q9WTS5,"Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]","Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]",GO:0005794; GO:0016605; GO:0007411; GO:0035584; GO:0050839; GO:0005911; GO:0043197; GO:0005783; GO:0030175; GO:0030426; GO:0007157; GO:0005887; GO:0000122; GO:0051491; GO:0045211; GO:0046982; GO:0042803; GO:0005102; GO:0006351,"Golgi apparatus; PML body; axon guidance; calcium-mediated signaling using intracellular calcium source; cell adhesion molecule binding; cell-cell junction; dendritic spine; endoplasmic reticulum; filopodium; growth cone; heterophilic cell-cell adhesion; integral to plasma membrane; negative regulation of transcription from RNA polymerase II promoter; positive regulation of filopodium assembly; postsynaptic membrane; protein heterodimerization activity; protein homodimerization activity; receptor binding; transcription, DNA-dependent",PF12661;PF06484;PF15636;,,,,,,,,,TEN2_MOUSE,Mus musculus (Mouse),"axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]" comp39522_c0_seq1,331,37.4622,0.95030792,10,4,,4.00E-11,P08361,Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Integrase p46 (IN)] (Fragment),Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Integrase p46 (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (Fragment),GO:0015074; GO:0075713; GO:0046872; GO:0003676; GO:0046718,DNA integration; establishment of integrated proviral latency; metal ion binding; nucleic acid binding; viral entry into host cell,PF00665;,,,,,,,,,POL_MLVCB,Cas-Br-E murine leukemia virus,DNA integration [GO:0015074]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp39537_c0_seq1,352,39.7727,0.57928673,1,25,,5.00E-22,Q64430,Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog),Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog),GO:0005524; GO:0042093; GO:0001568; GO:0001974; GO:0051216; GO:0006878; GO:0021702; GO:0030199; GO:0015677; GO:0004008; GO:0048813; GO:0010273; GO:0042417; GO:0048251; GO:0051542; GO:0042414; GO:0031069; GO:0016021; GO:0007626; GO:0048286; GO:0048553; GO:0043524; GO:0043005; GO:0043025; GO:0042421; GO:0018205; GO:0043473; GO:0005886; GO:0048554; GO:0021860; GO:0010468; GO:0002082; GO:0001836; GO:0019430; GO:0042428; GO:0016532; GO:0005802; GO:0030140; GO:0006568; GO:0006570,ATP binding; T-helper cell differentiation; blood vessel development; blood vessel remodeling; cartilage development; cellular copper ion homeostasis; cerebellar Purkinje cell differentiation; collagen fibril organization; copper ion import; copper-exporting ATPase activity; dendrite morphogenesis; detoxification of copper ion; dopamine metabolic process; elastic fiber assembly; elastin biosynthetic process; epinephrine metabolic process; hair follicle morphogenesis; integral to membrane; locomotory behavior; lung alveolus development; negative regulation of metalloenzyme activity; negative regulation of neuron apoptotic process; neuron projection; neuronal cell body; norepinephrine biosynthetic process; peptidyl-lysine modification; pigmentation; plasma membrane; positive regulation of metalloenzyme activity; pyramidal neuron development; regulation of gene expression; regulation of oxidative phosphorylation; release of cytochrome c from mitochondria; removal of superoxide radicals; serotonin metabolic process; superoxide dismutase copper chaperone activity; trans-Golgi network; trans-Golgi network transport vesicle; tryptophan metabolic process; tyrosine metabolic process,PF00122;PF00403;,,,,,,,,,ATP7A_MOUSE,Mus musculus (Mouse),ATP metabolic process [GO:0046034]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of neuron apoptotic process [GO:0043524]; neuron projection morphogenesis [GO:0048812]; norepinephrine biosynthetic process [GO:0042421]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of oxidoreductase activity [GO:0051353]; pyramidal neuron development [GO:0021860]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]; tyrosine metabolic process [GO:0006570] comp3959_c0_seq1,233,45.0644,0.51504984,3,5,,3.00E-16,Q54728,Uncharacterized oxidoreductase SP_1686 (EC 1.-.-.-),Uncharacterized oxidoreductase SP_1686 (EC 1.-.-.-),GO:0016491,oxidoreductase activity,PF01408;PF02894;,2.00E-16,CHOYP_BRAFLDRAFT_268591.1.1,,,,,,,Y1686_STRPN,Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4), comp39654_c0_seq1,203,53.202,0.92989634,0,8,,1.00E-29,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp39675_c0_seq1,375,44.5333,0.70534412,7,8,,7.00E-32,A6H8I0,Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22),Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22),GO:0007049; GO:0016568; GO:0008234; GO:0005634; GO:0006355; GO:0006351; GO:0004221; GO:0006511; GO:0008270,"cell cycle; chromatin modification; cysteine-type peptidase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding",PF00443;PF02148;,,,,,,,,,UBP22_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell cycle [GO:0007049]; histone deubiquitination [GO:0016578]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp39686_c0_seq1,251,46.2151,0.71592045,4,0,,1.00E-17,Q0IHV1,Inverted formin-2,Inverted formin-2,GO:0030036,actin cytoskeleton organization,PF06367;PF06371;PF02181;PF02205;,6.00E-18,CHOYP_INF2.2.5,,,,,,,INF2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),actin cytoskeleton organization [GO:0030036] comp39702_c0_seq1,231,45.4545,0.42963768,5,5,,3.00E-14,Q8WN22,DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1),GO:0005524; GO:0003677; GO:0006310; GO:0004677; GO:0006303; GO:0070419; GO:0005730,ATP binding; DNA binding; DNA recombination; DNA-dependent protein kinase activity; double-strand break repair via nonhomologous end joining; nonhomologous end joining complex; nucleolus,PF02259;PF02260;PF08163;PF00454;,1.00E-13,CHOYP_NEMVEDRAFT_V1G126379.2.2,,,,,,,PRKDC_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein phosphorylation [GO:0001933]; regulation of circadian rhythm [GO:0042752]; regulation of smooth muscle cell proliferation [GO:0048660]; rhythmic process [GO:0048511]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431] comp39706_c0_seq1,273,35.5311,0.5116782,1,11,,1.00E-07,A8MT65,Zinc finger protein 891,Zinc finger protein 891,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN891_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp39715_c0_seq1,276,69.9275,1.1952692,0,21,,1.00E-06,Q3S4A7,Histidine kinase 5 (EC 2.7.13.3) (Arabidopsis histidine kinase 5) (AtHK5) (Protein AUTHENTIC HIS-KINASE 5) (Protein CYTOKININ-INDEPENDENT 2),Histidine kinase 5 (EC 2.7.13.3) (Arabidopsis histidine kinase 5) (AtHK5) (Protein AUTHENTIC HIS-KINASE 5) (Protein CYTOKININ-INDEPENDENT 2),GO:0005524; GO:0009738; GO:0070301; GO:0071219; GO:0071732; GO:0009736; GO:0006952; GO:0009873; GO:0035556; GO:0009788; GO:0010105; GO:0000156; GO:0000155; GO:0005886; GO:0004673; GO:0090333; GO:0006355; GO:0048364; GO:0023014; GO:0005773,"ATP binding; abscisic acid mediated signaling pathway; cellular response to hydrogen peroxide; cellular response to molecule of bacterial origin; cellular response to nitric oxide; cytokinin mediated signaling pathway; defense response; ethylene mediated signaling pathway; intracellular signal transduction; negative regulation of abscisic acid mediated signaling pathway; negative regulation of ethylene mediated signaling pathway; phosphorelay response regulator activity; phosphorelay sensor kinase activity; plasma membrane; protein histidine kinase activity; regulation of stomatal closure; regulation of transcription, DNA-dependent; root development; signal transduction by phosphorylation; vacuole",PF02518;PF00512;PF00072;,,,,,,,,,AHK5_ARATH,Arabidopsis thaliana (Mouse-ear cress),abscisic acid-activated signaling pathway [GO:0009738]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to nitric oxide [GO:0071732]; cytokinin-activated signaling pathway [GO:0009736]; defense response [GO:0006952]; ethylene-activated signaling pathway [GO:0009873]; negative regulation of abscisic acid-activated signaling pathway [GO:0009788]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; regulation of stomatal closure [GO:0090333]; root development [GO:0048364] comp39724_c1_seq1,392,47.7041,0.22586354,24,0,,9.00E-08,Q4G0Z9,MCM domain-containing protein 2,MCM domain-containing protein 2,GO:0005524; GO:0003677; GO:0006260,ATP binding; DNA binding; DNA replication,PF00493;,,,,,,,,,MCMD2_HUMAN,Homo sapiens (Human),DNA replication [GO:0006260] comp39746_c0_seq1,405,39.7531,0.76483983,5,14,,4.00E-09,Q3MIX3,Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),GO:0016021; GO:0016301; GO:0005739; GO:0004674,integral to membrane; kinase activity; mitochondrion; protein serine/threonine kinase activity,PF03109;,,,,,,,,,ADCK5_HUMAN,Homo sapiens (Human), comp39800_c0_seq1,213,44.6009,0.39195003,7,3,,4.00E-26,P41233,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0071222; GO:0071300; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0007040; GO:0045121; GO:0002790; GO:0045335; GO:0006911; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lysosome organization; membrane raft; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,5.00E-31,CHOYP_ABCA1.3.3,,,,,,,ABCA1_MOUSE,Mus musculus (Mouse),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp39806_c0_seq1,227,72.6872,0.97323054,0,13,,6.00E-06,P33663,Laccase domain protein PA4543,Laccase domain protein PA4543,,,PF02578;,,,,,,,,,Y4543_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), comp39813_c0_seq1,487,43.1211,0.40364107,13,8,,1.00E-21,Q9H2Y9,Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15),Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15),GO:0016021; GO:0005886; GO:0005215,integral to membrane; plasma membrane; transporter activity,PF07648;PF03137;,7.00E-27,CHOYP_MYSP.9.9,,,,,,,SO5A1_HUMAN,Homo sapiens (Human),sodium-independent organic anion transport [GO:0043252] comp39822_c0_seq1,360,43.6111,0.78478866,8,8,,3.00E-32,Q9BXS9,Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1),Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1),GO:0030165; GO:0038166; GO:0015301; GO:0016324; GO:0016323; GO:0015106; GO:0031526; GO:0071320; GO:0071332; GO:0071346; GO:0005254; GO:0034707; GO:0015108; GO:0030659; GO:0005783; GO:0042045; GO:0015660; GO:0015659; GO:0016021; GO:0005887; GO:0050892; GO:0051454; GO:0015797; GO:0019531; GO:0046724; GO:0005886; GO:2001150; GO:0070528; GO:0051453; GO:0008271; GO:0048240; GO:0097225; GO:0015116; GO:0008272; GO:0030321; GO:0012506,PDZ domain binding; angiotensin-mediated signaling pathway; anion:anion antiporter activity; apical plasma membrane; basolateral plasma membrane; bicarbonate transmembrane transporter activity; brush border membrane; cellular response to cAMP; cellular response to fructose stimulus; cellular response to interferon-gamma; chloride channel activity; chloride channel complex; chloride transmembrane transporter activity; cytoplasmic vesicle membrane; endoplasmic reticulum; epithelial fluid transport; formate efflux transmembrane transporter activity; formate uptake transmembrane transporter activity; integral to membrane; integral to plasma membrane; intestinal absorption; intracellular pH elevation; mannitol transport; oxalate transmembrane transporter activity; oxalic acid secretion; plasma membrane; positive regulation of dipeptide transmembrane transport; protein kinase C signaling cascade; regulation of intracellular pH; secondary active sulfate transmembrane transporter activity; sperm capacitation; sperm midpiece; sulfate transmembrane transporter activity; sulfate transport; transepithelial chloride transport; vesicle membrane,PF01740;PF00916;,,,,,,,,,S26A6_HUMAN,Homo sapiens (Human),angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to fructose stimulus [GO:0071332]; cellular response to interferon-gamma [GO:0071346]; chloride transport [GO:0006821]; epithelial fluid transport [GO:0042045]; formate transport [GO:0015724]; intestinal absorption [GO:0050892]; intracellular pH elevation [GO:0051454]; ion transport [GO:0006811]; mannitol transport [GO:0015797]; oxalate transport [GO:0019532]; oxalic acid secretion [GO:0046724]; positive regulation of dipeptide transmembrane transport [GO:2001150]; protein kinase C signaling [GO:0070528]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]; sulfate transport [GO:0008272]; transepithelial chloride transport [GO:0030321]; transepithelial transport [GO:0070633] comp39849_c0_seq1,282,48.227,0.26799579,5,4,,1.00E-16,Q3SYU9,Major vault protein (MVP),Major vault protein (MVP),GO:0005737; GO:0005634; GO:0030529,cytoplasm; nucleus; ribonucleoprotein complex,PF11978;PF01505;,,,,,,,,,MVP_BOVIN,Bos taurus (Bovine), comp39859_c0_seq1,233,70.8155,1.16578234,0,15,,1.00E-15,Q9FY46,"Sulfate transporter 4.1, chloroplastic (AST82)","Sulfate transporter 4.1, chloroplastic (AST82)",GO:0031969; GO:0016021; GO:0006950; GO:0008271; GO:0008272; GO:0015293,chloroplast membrane; integral to membrane; response to stress; secondary active sulfate transmembrane transporter activity; sulfate transport; symporter activity,PF01740;PF00916;,,,,,,,,,SUT41_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp39886_c0_seq1,228,54.8246,1.00182061,1,7,,9.00E-23,P46920,Glycine betaine transport ATP-binding protein OpuAA (EC 3.6.3.32) (Quaternary-amine-transporting ATPase),Glycine betaine transport ATP-binding protein OpuAA (EC 3.6.3.32) (Quaternary-amine-transporting ATPase),GO:0005524; GO:0006200; GO:0031460; GO:0016020; GO:0015418,ATP binding; ATP catabolic process; glycine betaine transport; membrane; quaternary-ammonium-compound-transporting ATPase activity,PF00005;PF00571;,,,,,,,,,OPUAA_BACSU,Bacillus subtilis (strain 168),amino acid transport [GO:0006865]; glycine betaine transport [GO:0031460] comp39888_c0_seq1,346,41.0405,0.62001709,8,6,,2.00E-07,Q01177,"Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]","Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]",GO:0006915; GO:0007596; GO:0004175; GO:0022617; GO:0005615; GO:0031232; GO:0042730; GO:0043231; GO:0060716; GO:0071674; GO:0046716; GO:0045445; GO:0010812; GO:0051918; GO:0005886; GO:0051919; GO:0051603; GO:0004252; GO:0042246; GO:0048771; GO:0060707,apoptotic process; blood coagulation; endopeptidase activity; extracellular matrix disassembly; extracellular space; extrinsic to external side of plasma membrane; fibrinolysis; intracellular membrane-bounded organelle; labyrinthine layer blood vessel development; mononuclear cell migration; muscle cell cellular homeostasis; myoblast differentiation; negative regulation of cell-substrate adhesion; negative regulation of fibrinolysis; plasma membrane; positive regulation of fibrinolysis; proteolysis involved in cellular protein catabolic process; serine-type endopeptidase activity; tissue regeneration; tissue remodeling; trophoblast giant cell differentiation,PF00051;PF00024;PF00089;,,,,,,,,,PLMN_RAT,Rattus norvegicus (Rat),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trophoblast giant cell differentiation [GO:0060707] comp39920_c0_seq1,513,37.8168,0.54651989,9,9,,2.00E-10,Q8C8N2,Protein SCAI (Suppressor of cancer cell invasion protein),Protein SCAI (Suppressor of cancer cell invasion protein),GO:0005737; GO:0016021; GO:0035024; GO:0030336; GO:0005634; GO:0006355; GO:0003714; GO:0006351,"cytoplasm; integral to membrane; negative regulation of Rho protein signal transduction; negative regulation of cell migration; nucleus; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",PF12070;,1.00E-17,CHOYP_ISCW_ISCW022658.1.2,,,,,,,SCAI_MOUSE,Mus musculus (Mouse),"negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp39924_c0_seq1,309,33.9806,1.27050511,5,7,,2.00E-07,Q7Z2Y8,Interferon-induced very large GTPase 1 (Interferon-induced very large GTPase pseudogene 1),Interferon-induced very large GTPase 1 (Interferon-induced very large GTPase pseudogene 1),GO:0005525; GO:0005829; GO:0005634,GTP binding; cytosol; nucleus,,,,,,,,,,GVIN1_HUMAN,Homo sapiens (Human), comp39940_c0_seq1,231,35.4978,0.62987606,3,11,,,,,,,,,3.00E-28,CHOYP_contig_025445,2.00E-15,ruditapes_c3910,,,,,,, comp39995_c0_seq1,337,35.3116,0.59125885,12,7,,9.00E-07,Q9NP78,ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL),ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL),GO:0005524; GO:0042288; GO:0042825; GO:0046978; GO:0046979; GO:0005765; GO:0015421; GO:0042605; GO:0005886; GO:0001916; GO:0042803; GO:0015031; GO:0046980,ATP binding; MHC class I protein binding; TAP complex; TAP1 binding; TAP2 binding; lysosomal membrane; oligopeptide-transporting ATPase activity; peptide antigen binding; plasma membrane; positive regulation of T cell mediated cytotoxicity; protein homodimerization activity; protein transport; tapasin binding,PF00664;PF00005;,,,,,,,,,ABCB9_HUMAN,Homo sapiens (Human),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]" comp40012_c0_seq1,244,62.7049,1.10938819,1,15,,2.00E-10,P0AE76,Bifunctional adenosylcobalamin biosynthesis protein CobU (Adenosylcobinamide kinase) (EC 2.7.1.156) (Adenosylcobinamide-phosphate guanylyltransferase) (EC 2.7.7.62),Bifunctional adenosylcobalamin biosynthesis protein CobU (Adenosylcobinamide kinase) (EC 2.7.1.156) (Adenosylcobinamide-phosphate guanylyltransferase) (EC 2.7.7.62),GO:0005524; GO:0005525; GO:0043752; GO:0009236; GO:0008819; GO:0008820; GO:0006779; GO:0006974,ATP binding; GTP binding; adenosylcobinamide kinase activity; cobalamin biosynthetic process; cobinamide kinase activity; cobinamide phosphate guanylyltransferase activity; porphyrin-containing compound biosynthetic process; response to DNA damage stimulus,PF02283;,,,,,,,,,COBU_ECOLI,Escherichia coli (strain K12),cellular response to DNA damage stimulus [GO:0006974]; cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779] comp40048_c0_seq1,201,36.8159,1.04511086,0,11,,1.00E-05,P05179,Cytochrome P450 2C7 (EC 1.14.14.1) (CYPIIC7) (Cytochrome P450F) (PTF1),Cytochrome P450 2C7 (EC 1.14.14.1) (CYPIIC7) (Cytochrome P450F) (PTF1),GO:0070330; GO:0005789; GO:0020037; GO:0043231; GO:0005506; GO:0042493; GO:0045471; GO:0032496; GO:0007584; GO:0014070; GO:0043434; GO:0032526,aromatase activity; endoplasmic reticulum membrane; heme binding; intracellular membrane-bounded organelle; iron ion binding; response to drug; response to ethanol; response to lipopolysaccharide; response to nutrient; response to organic cyclic compound; response to peptide hormone stimulus; response to retinoic acid,PF00067;,,,,,,,,,CP2C7_RAT,Rattus norvegicus (Rat),epoxygenase P450 pathway [GO:0019373]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to retinoic acid [GO:0032526] comp40066_c0_seq1,303,42.5743,0.59259905,7,0,,,,,,,,,6.00E-13,CHOYP_LOC100889942.1.1,,,,,,,,, comp40122_c0_seq1,287,41.8118,0.3200928,3,8,,2.00E-15,Q9DG25,Popeye domain-containing protein 3 (Popeye protein 3),Popeye domain-containing protein 3 (Popeye protein 3),GO:0016021,integral to membrane,PF04831;,,,,,,,,,POPD3_CHICK,Gallus gallus (Chicken),regulation of membrane potential [GO:0042391] comp40127_c0_seq1,258,47.6744,0.54873706,4,11,,6.00E-10,Q9W6V5,Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Supporting-cell antigen),Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Supporting-cell antigen),GO:0005911; GO:0016021; GO:0043407; GO:0050860; GO:0042059; GO:0051898; GO:0035335; GO:0016791; GO:0005886; GO:0048008; GO:0051894; GO:0004725; GO:0032587,cell-cell junction; integral to membrane; negative regulation of MAP kinase activity; negative regulation of T cell receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of protein kinase B signaling cascade; peptidyl-tyrosine dephosphorylation; phosphatase activity; plasma membrane; platelet-derived growth factor receptor signaling pathway; positive regulation of focal adhesion assembly; protein tyrosine phosphatase activity; ruffle membrane,PF00041;PF00102;,,,,,,,,,PTPRJ_CHICK,Gallus gallus (Chicken),negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell receptor signaling pathway [GO:0050860]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell adhesion [GO:0045785]; positive regulation of focal adhesion assembly [GO:0051894] comp40147_c0_seq1,494,43.3198,0.4464304,17,30,,6.00E-46,O75131,Copine-3 (Copine III),Copine-3 (Copine III),GO:0005544; GO:0005829; GO:0006629; GO:0004674; GO:0005215; GO:0016192,calcium-dependent phospholipid binding; cytosol; lipid metabolic process; protein serine/threonine kinase activity; transporter activity; vesicle-mediated transport,PF00168;PF07002;,,,,,,,,,CPNE3_HUMAN,Homo sapiens (Human),cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; glycerophospholipid biosynthetic process [GO:0046474]; lipid metabolic process [GO:0006629]; positive regulation of cell migration [GO:0030335]; vesicle-mediated transport [GO:0016192] comp40204_c1_seq1,263,38.7833,0.71490395,5,0,,3.00E-12,Q8NDZ4,Deleted in autism protein 1 (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF),Deleted in autism protein 1 (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF),GO:0030126; GO:0060038; GO:0005615; GO:0014066,COPI vesicle coat; cardiac muscle cell proliferation; extracellular space; regulation of phosphatidylinositol 3-kinase cascade,PF12260;,,,,,,,,,DIA1_HUMAN,Homo sapiens (Human),cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp40234_c0_seq1,356,41.573,0.52164795,7,15,,1.00E-26,Q6AX23,Sulfhydryl oxidase 2 (EC 1.8.3.2) (Quiescin Q6-like protein 1),Sulfhydryl oxidase 2 (EC 1.8.3.2) (Quiescin Q6-like protein 1),GO:0045454; GO:0016021; GO:0016972,cell redox homeostasis; integral to membrane; thiol oxidase activity,PF04777;PF00085;,,,,,,,,,QSOX2_XENLA,Xenopus laevis (African clawed frog),cell redox homeostasis [GO:0045454] comp40242_c0_seq1,217,59.447,0.95014124,0,13,,7.00E-10,Q44270,DNA gyrase subunit B (EC 5.99.1.3) (Fragment),DNA gyrase subunit B (EC 5.99.1.3) (Fragment),GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0005737,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; cytoplasm,PF00204;PF01751;,,,,,,,,,GYRB_ACIG3,Acinetobacter pittii (Acinetobacter genomosp. 3),DNA topological change [GO:0006265] comp40275_c0_seq1,283,46.6431,0.32969996,4,9,,2.00E-47,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-55,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp40293_c0_seq1,201,46.2687,0.57171226,0,12,,1.00E-26,P70426,GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1),GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1),GO:0005525; GO:0003924; GO:0005886; GO:0007264,GTP binding; GTPase activity; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RIT1_MOUSE,Mus musculus (Mouse),Ras protein signal transduction [GO:0007265] comp40293_c1_seq1,208,41.8269,0.79082909,1,4,,2.00E-07,Q55BW0,Ras-related protein rapC,Ras-related protein rapC,GO:0005525; GO:0003924; GO:0005886; GO:0007264,GTP binding; GTPase activity; plasma membrane; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAPC_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp40305_c0_seq1,317,48.5804,0.59158377,6,0,,,,,,,,,9.00E-11,CHOYP_BRAFLDRAFT_117157.1.3,,,,,,,,, comp40305_c1_seq1,410,49.7561,0.7395086,7,11,,1.00E-24,Q502W6,von Willebrand factor A domain-containing protein 3B,von Willebrand factor A domain-containing protein 3B,,,PF15057;PF13768;,,,,,,,,,VWA3B_HUMAN,Homo sapiens (Human), comp40310_c0_seq1,354,39.2655,0.44375354,4,9,,2.00E-14,Q9C0D6,FH2 domain-containing protein 1,FH2 domain-containing protein 1,,,PF02181;,,,,,,,,,FHDC1_HUMAN,Homo sapiens (Human), comp40311_c0_seq1,408,39.7059,0.31245413,8,47,,1.00E-11,Q8VHI5,Vitrin,Vitrin,GO:0030198; GO:0005539; GO:0005614; GO:0010811,extracellular matrix organization; glycosaminoglycan binding; interstitial matrix; positive regulation of cell-substrate adhesion,PF03815;PF00092;,,,,,,,,,VITRN_MOUSE,Mus musculus (Mouse),extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811] comp40383_c0_seq1,544,46.875,1.17385012,12,6,,3.00E-25,Q90963,Paired mesoderm homeobox protein 2 (PRX-2) (Fragment),Paired mesoderm homeobox protein 2 (PRX-2) (Fragment),GO:0007275; GO:0005634; GO:0043565; GO:0003700,multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;PF03826;,3.00E-33,CHOYP_LOC100547648.1.1,,,,,,,PRRX2_CHICK,Gallus gallus (Chicken),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp40403_c0_seq2,330,37.5758,0,2,2,,2.00E-12,Q6ZQX7,Uncharacterized protein C17orf97,Protein LIAT1 (Ligand of ATE1 protein),,,,,,,,,,,,CQ097_HUMAN,Homo sapiens (Human),protein arginylation [GO:0016598] comp4042_c0_seq1,218,38.5321,0.62217218,6,0,,2.00E-42,Q90718,Serum response factor (SRF) (Fragment),Serum response factor (SRF) (Fragment),GO:0003677; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00319;,8.00E-54,CHOYP_LOC100370177.1.1,,,,,,,SRF_CHICK,Gallus gallus (Chicken),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp40451_c0_seq1,309,41.4239,0.22755315,11,0,,2.00E-33,Q10569,Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit),GO:0003730; GO:0006379; GO:0005847; GO:0006378,mRNA 3'-UTR binding; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA polyadenylation,PF03178;,1.00E-21,CHOYP_CPSF1.1.1,,,,,,,CPSF1_BOVIN,Bos taurus (Bovine),mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378] comp40467_c0_seq1,467,44.9679,0.34157624,19,0,,2.00E-27,Q95216,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (RUSH-1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (RUSH-1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),GO:0005524; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005730; GO:0005654; GO:0016567; GO:0006351; GO:0008270,"ATP binding; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleolus; nucleoplasm; protein ubiquitination; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;PF00097;,2.00E-26,CHOYP_HLTF.1.1,,,,,,,HLTF_RABIT,Oryctolagus cuniculus (Rabbit),"chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp40507_c0_seq1,245,44.898,0.57229268,0,16,,6.00E-20,P48067,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9),GO:0015375; GO:0005887; GO:0005328,glycine:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,SC6A9_HUMAN,Homo sapiens (Human),"glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]" comp40510_c0_seq1,338,42.8994,0.27207301,3,17,,1.00E-21,Q9WU79,"Proline dehydrogenase 1, mitochondrial (EC 1.5.99.8) (Proline oxidase)","Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase)",GO:0071949; GO:0006537; GO:0005743; GO:0005759; GO:0010133; GO:0004657,FAD binding; glutamate biosynthetic process; mitochondrial inner membrane; mitochondrial matrix; proline catabolic process to glutamate; proline dehydrogenase activity,PF01619;,4.00E-15,CHOYP_LOC101078914.1.1,,,,,,,PROD_MOUSE,Mus musculus (Mouse),proline catabolic process to glutamate [GO:0010133] comp40569_c0_seq1,367,47.4114,0.39416546,14,1,,7.00E-49,Q6PCN7,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (P113) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (P113) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein),GO:0005524; GO:0016887; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005730; GO:0005654; GO:0016567; GO:0006357; GO:0006351; GO:0008270,"ATP binding; ATPase activity; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleolus; nucleoplasm; protein ubiquitination; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;,6.00E-33,CHOYP_HLTF.1.1,,,,,,,HLTF_MOUSE,Mus musculus (Mouse),chromatin modification [GO:0016568]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp40571_c0_seq1,528,39.2045,0.77414912,9,11,,2.00E-13,Q8RB30,Macro domain-containing protein TTE0995,Macro domain-containing protein TTE0995,,,PF01661;,,,,,,,,,Y995_THETN,Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis), comp40583_c0_seq1,265,38.4906,0.20580564,7,22,,6.00E-07,O94889,Kelch-like protein 18,Kelch-like protein 18,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH18_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp40624_c0_seq1,232,40.0862,1.30048928,0,17,,5.00E-07,Q8BSL4,Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5),Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5),GO:0000139; GO:0008467; GO:0015015; GO:0016021; GO:0050819; GO:0006477; GO:0046596,"Golgi membrane; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; integral to membrane; negative regulation of coagulation; protein sulfation; regulation of viral entry into host cell",PF00685;,,,,,,,,,HS3S5_MOUSE,Mus musculus (Mouse),"heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]" comp40641_c0_seq1,403,44.9132,0.5430141,4,19,,6.00E-33,Q68FG0,Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127 homolog),Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127 homolog),GO:0030054; GO:0005737; GO:0046872; GO:0007528; GO:0005634; GO:0045211; GO:0021522,cell junction; cytoplasm; metal ion binding; neuromuscular junction development; nucleus; postsynaptic membrane; spinal cord motor neuron differentiation,PF10146;,4.00E-29,CHOYP_ZC4H2.1.1,,,,,,,ZC4H2_MOUSE,Mus musculus (Mouse),nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; spinal cord motor neuron differentiation [GO:0021522] comp40667_c0_seq1,317,41.3249,0.91292775,0,26,,2.00E-39,Q9Y3Z3,Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1),Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1),GO:0003723; GO:0051607; GO:0006955; GO:0045087; GO:0008152; GO:0046872; GO:0005634; GO:0008081; GO:0045088,RNA binding; defense response to virus; immune response; innate immune response; metabolic process; metal ion binding; nucleus; phosphoric diester hydrolase activity; regulation of innate immune response,PF01966;PF07647;,1.00E-33,CHOYP_SAMH1.1.12,,,,,,,SAMH1_HUMAN,Homo sapiens (Human),dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; immune response [GO:0006955]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; type I interferon signaling pathway [GO:0060337] comp40693_c0_seq1,260,47.3077,0.62143776,2,14,,6.00E-41,O75600,"2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)","2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)",GO:0019518; GO:0009058; GO:0006520; GO:0008890; GO:0005739; GO:0005634; GO:0030170,L-threonine catabolic process to glycine; biosynthetic process; cellular amino acid metabolic process; glycine C-acetyltransferase activity; mitochondrion; nucleus; pyridoxal phosphate binding,PF00155;,7.00E-43,CHOYP_ISCW_ISCW015295.1.1,,,,,,,KBL_HUMAN,Homo sapiens (Human),biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; L-threonine catabolic process to glycine [GO:0019518] comp40768_c0_seq1,287,42.1603,0.55537864,4,0,,5.00E-14,Q6DFK0,Putative sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9),Sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9),GO:0006865; GO:0016021; GO:0006814,amino acid transport; integral to membrane; sodium ion transport,PF01490;,1.00E-21,CHOYP_LOC574943.1.1,,,,,,,S38A9_XENLA,Xenopus laevis (African clawed frog),amino acid transmembrane transport [GO:0003333]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of TOR signaling [GO:0032008] comp40800_c0_seq1,252,42.0635,0.81091021,2,11,,2.00E-14,Q6DHL5,Leucine-rich repeat-containing protein 57,Leucine-rich repeat-containing protein 57,,,PF13855;,,,,,,,,,LRC57_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp40805_c0_seq1,323,45.5108,0.45161723,28,0,,2.00E-12,P00982,Protease inhibitor K (Dendrotoxin delta-DaTX) (Toxin C13S1C3) (Venom basic protease inhibitor K),Kunitz-type serine protease inhibitor homolog delta-dendrotoxin (Delta-DTX) (Dendrotoxin delta-DaTX) (Protease inhibitor K) (Toxin C13S1C3) (Venom basic protease inhibitor K),GO:0005576; GO:0004867,extracellular region; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,IVBIK_DENAN,Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps), comp4081_c0_seq1,225,38.2222,0.36669194,4,0,,4.00E-09,Q9Y5E4,Protocadherin beta-5 (PCDH-beta-5),Protocadherin beta-5 (PCDH-beta-5),GO:0005509; GO:0016339; GO:0007156; GO:0016021; GO:0005886; GO:0007416; GO:0007268,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to membrane; plasma membrane; synapse assembly; synaptic transmission,PF00028;PF08266;PF16492;,,,,,,,,,PCDB5_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416] comp40837_c0_seq1,308,41.8831,0.15007443,7,8,,4.00E-20,Q8C456,WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein),WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein),GO:0035085; GO:0060271; GO:0005856; GO:0005886; GO:0016476; GO:0032880; GO:0032185,cilium axoneme; cilium morphogenesis; cytoskeleton; plasma membrane; regulation of embryonic cell shape; regulation of protein localization; septin cytoskeleton organization,PF11768;,8.00E-18,CHOYP_FRITZ.1.1,,,,,,,FRITZ_MOUSE,Mus musculus (Mouse),auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cardiovascular system development [GO:0072358]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cilium organization [GO:0044782]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; glomerular visceral epithelial cell migration [GO:0090521]; kidney development [GO:0001822]; nervous system development [GO:0007399]; palate development [GO:0060021]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224] comp40844_c0_seq1,277,47.2924,0.52727098,1,1,,3.00E-31,Q5RDF5,Juxtaposed with another zinc finger protein 1,Juxtaposed with another zinc finger protein 1,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,JAZF1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"lipid metabolic process [GO:0006629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp40854_c0_seq1,242,49.1736,0.85016029,2,0,,8.00E-19,P46530,Neurogenic locus notch homolog protein 1,Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)],GO:0007219; GO:0005509; GO:0007368; GO:0031017; GO:0021986; GO:0055016; GO:0016021; GO:0001840; GO:0048936; GO:0048337; GO:0004872; GO:0042663; GO:0048259; GO:0006355; GO:0021523; GO:0001756; GO:0021531; GO:0006351,"Notch signaling pathway; calcium ion binding; determination of left/right symmetry; exocrine pancreas development; habenula development; hypochord development; integral to membrane; neural plate development; peripheral nervous system neuron axonogenesis; positive regulation of mesodermal cell fate specification; receptor activity; regulation of endodermal cell fate specification; regulation of receptor-mediated endocytosis; regulation of transcription, DNA-dependent; somatic motor neuron differentiation; somitogenesis; spinal cord radial glial cell differentiation; transcription, DNA-dependent",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal aorta development [GO:0035907]; exocrine pancreas development [GO:0031017]; generation of neurons [GO:0048699]; habenula development [GO:0021986]; hematopoietic progenitor cell differentiation [GO:0002244]; hypochord development [GO:0055016]; negative regulation of neurogenesis [GO:0050768]; neural plate development [GO:0001840]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; positive regulation of mesodermal cell fate specification [GO:0048337]; regulation of endodermal cell fate specification [GO:0042663]; regulation of receptor-mediated endocytosis [GO:0048259]; regulation of transcription, DNA-templated [GO:0006355]; somatic motor neuron differentiation [GO:0021523]; somitogenesis [GO:0001756]; spinal cord radial glial cell differentiation [GO:0021531]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron differentiation [GO:0021514]" comp40855_c0_seq1,215,44.6512,0.37500811,7,3,,1.00E-13,A6NCI4,von Willebrand factor A domain-containing protein 3A,von Willebrand factor A domain-containing protein 3A,GO:0005576,extracellular region,PF13768;,1.00E-19,CHOYP_LOC592709.1.1,,,,,,,VWA3A_HUMAN,Homo sapiens (Human), comp40857_c0_seq1,399,43.1078,0.44126036,8,14,,1.00E-13,Q6ZPQ6,"Membrane-associated phosphatidylinositol transfer protein 2 (Drosophila retinal degeneration B homolog 2) (RdgB2) (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)","Membrane-associated phosphatidylinositol transfer protein 2 (Drosophila retinal degeneration B homolog 2) (RdgB2) (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)",GO:0005737; GO:0005856; GO:0012505; GO:0005622; GO:0043231; GO:0016020; GO:0046872; GO:0005543; GO:0006810,cytoplasm; cytoskeleton; endomembrane system; intracellular; intracellular membrane-bounded organelle; membrane; metal ion binding; phospholipid binding; transport,PF02862;PF02121;,,,,,,,,,PITM2_MOUSE,Mus musculus (Mouse),transport [GO:0006810] comp40889_c0_seq1,284,39.0845,0.47980393,5,11,,1.00E-20,Q9P2E3,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,,,,,,,,,ZNFX1_HUMAN,Homo sapiens (Human), comp40890_c0_seq1,474,43.8819,0.21960338,15,6,,9.00E-61,Q5RDU4,Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17),Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17),GO:0003950,NAD+ ADP-ribosyltransferase activity,PF00644;,4.00E-30,CHOYP_PARP8.1.1,,,,,,,PARP6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp40902_c0_seq1,964,41.7012,0.31463216,27,54,,9.00E-118,Q7TSV4,Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-1) (Phosphopentomutase) (EC 5.4.2.7),Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-1) (Phosphopentomutase) (EC 5.4.2.7),GO:0016052; GO:0005829; GO:0046386; GO:0006006; GO:0000287; GO:0004614; GO:0008973,carbohydrate catabolic process; cytosol; deoxyribose phosphate catabolic process; glucose metabolic process; magnesium ion binding; phosphoglucomutase activity; phosphopentomutase activity,PF02878;PF02879;PF02880;PF00408;,8.00E-49,CHOYP_PGM2.1.1,,,,,,,PGM2_MOUSE,Mus musculus (Mouse),deoxyribose phosphate catabolic process [GO:0046386]; glucose metabolic process [GO:0006006] comp40910_c0_seq1,474,47.6793,0.6729664,9,20,,8.00E-11,Q8R508,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT3_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp40919_c0_seq1,527,47.6281,0.37374652,22,15,,3.00E-35,Q5RGJ6,WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53),WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53),GO:0071203,WASH complex,PF10152;,4.00E-24,CHOYP_CCD53.1.1,,,,,,,CCD53_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp40927_c0_seq1,254,42.126,0.72035015,0,23,,,,,,,,,,,1.00E-31,ruditapes_c7472,,,,,,, comp40933_c0_seq1,264,43.9394,0.39576434,7,5,,1.00E-11,Q7TN83,Synaptotagmin-16 (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein),Synaptotagmin-16 (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein),GO:0016021; GO:0005543; GO:0042803,integral to membrane; phospholipid binding; protein homodimerization activity,PF00168;,7.00E-30,CHOYP_LOC100369472.2.2,,,,,,,SYT16_MOUSE,Mus musculus (Mouse),exocytosis [GO:0006887]; vesicle fusion [GO:0006906] comp40960_c0_seq1,659,47.4962,0.48616907,19,2,,3.00E-52,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,2.00E-60,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp40979_c0_seq1,464,46.7672,0.59615662,0,8,,1.00E-05,Q684R7,FRAS1-related extracellular matrix protein 1 (Protein QBRICK),FRAS1-related extracellular matrix protein 1 (Protein QBRICK),GO:0005604; GO:0030246; GO:0007154; GO:0007160; GO:0097094; GO:0016021; GO:0046872,basement membrane; carbohydrate binding; cell communication; cell-matrix adhesion; craniofacial suture morphogenesis; integral to membrane; metal ion binding,PF03160;PF00059;,,,,,,,,,FREM1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] comp40979_c0_seq2,452,46.6814,0.5726956,7,0,,7.00E-14,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp40991_c0_seq1,421,42.2803,0.60090954,5,25,,5.00E-35,Q7L9B9,Endonuclease/exonuclease/phosphatase family domain-containing protein 1,Endonuclease/exonuclease/phosphatase family domain-containing protein 1,GO:0003677; GO:0006281,DNA binding; DNA repair,PF03372;,,,,,,,,,EEPD1_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281] comp40992_c0_seq1,276,43.4783,0.76966834,3,15,,4.00E-17,O95427,GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GO:0006501; GO:0005789; GO:0016021; GO:0016254; GO:0016740,C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane; transferase activity,PF01663;PF04987;,,,,,,,,,PIGN_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp41032_c0_seq1,578,44.4637,0.3506976,9,3,,4.00E-36,O95544,NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase),NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase),GO:0005524; GO:0046034; GO:0019674; GO:0003951; GO:0006741; GO:0005829; GO:0046872; GO:0006767,ATP binding; ATP metabolic process; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; cytosol; metal ion binding; water-soluble vitamin metabolic process,PF01513;,4.00E-25,CHOYP_LOC100875114.1.1,3.00E-12,ruditapes_c29740,,,,,NADK_HUMAN,Homo sapiens (Human),ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310] comp41036_c0_seq1,323,46.4396,0.63462147,7,22,,,,,,,,,5.00E-14,CHOYP_ISCW_ISCW000333.1.1,,,,,,,,, comp41092_c0_seq1,212,37.7358,1.00813602,0,18,,7.00E-10,P81900,cAMP-dependent protein kinase type II regulatory subunit,cAMP-dependent protein kinase type II regulatory subunit,GO:0007411; GO:0048148; GO:0048149; GO:0030552; GO:0005952; GO:0008603; GO:0005737; GO:0045475,axon guidance; behavioral response to cocaine; behavioral response to ethanol; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; cytoplasm; locomotor rhythm,PF00027;,,,,,,,,,KAPR2_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; rhythmic behavior [GO:0007622] comp41145_c0_seq1,236,45.7627,1.086792,3,8,,1.00E-22,Q4R632,Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2),GO:0005829; GO:0004181; GO:0006508; GO:0008270,cytosol; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,4.00E-20,CHOYP_LOC580601.4.5,,,,,,,CBPC2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),protein side chain deglutamylation [GO:0035610] comp41172_c0_seq1,378,47.619,0.60895248,6,4,,4.00E-32,Q59I64,Y+L amino acid transporter 2 (Solute carrier family 7 member 6) (zfSlc7a6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2),Y+L amino acid transporter 2 (Solute carrier family 7 member 6) (zfSlc7a6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2),GO:0015171; GO:0016323; GO:0016021,amino acid transmembrane transporter activity; basolateral plasma membrane; integral to membrane,PF13520;,4.00E-16,CHOYP_LAT1.2.2,,,,,,,YLAT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp41178_c0_seq1,370,51.0811,1.16327837,4,16,,1.00E-58,P23824,GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b),GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b),GO:0001077; GO:0000980; GO:0021533; GO:0001709; GO:0048469; GO:0021954; GO:0003682; GO:0060216; GO:0001892; GO:0035854; GO:0048873; GO:0042472; GO:0045746; GO:0045599; GO:0070345; GO:0045650; GO:2000178; GO:0000122; GO:0048663; GO:0005634; GO:0021983; GO:0045766; GO:0045648; GO:0045654; GO:0043234; GO:0035065; GO:0060872; GO:0035019; GO:0001655; GO:0021514; GO:0008270,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding; cell differentiation in hindbrain; cell fate determination; cell maturation; central nervous system neuron development; chromatin binding; definitive hemopoiesis; embryonic placenta development; eosinophil fate commitment; homeostasis of number of cells within a tissue; inner ear morphogenesis; negative regulation of Notch signaling pathway; negative regulation of fat cell differentiation; negative regulation of fat cell proliferation; negative regulation of macrophage differentiation; negative regulation of neural precursor cell proliferation; negative regulation of transcription from RNA polymerase II promoter; neuron fate commitment; nucleus; pituitary gland development; positive regulation of angiogenesis; positive regulation of erythrocyte differentiation; positive regulation of megakaryocyte differentiation; protein complex; regulation of histone acetylation; semicircular canal development; somatic stem cell maintenance; urogenital system development; ventral spinal cord interneuron differentiation; zinc ion binding,PF00320;,6.00E-46,CHOYP_GATA2.2.2,,,,,,,GATA2_CHICK,Gallus gallus (Chicken),anatomical structure formation involved in morphogenesis [GO:0048646]; cell development [GO:0048468]; cell differentiation in hindbrain [GO:0021533]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; cell maturation [GO:0048469]; central nervous system neuron development [GO:0021954]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; definitive hemopoiesis [GO:0060216]; digestive tract development [GO:0048565]; eosinophil fate commitment [GO:0035854]; GABAergic neuron differentiation [GO:0097154]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; inner ear morphogenesis [GO:0042472]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; organ morphogenesis [GO:0009887]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of forebrain neuron differentiation [GO:2000977]; regulation of histone acetylation [GO:0035065]; regulation of primitive erythrocyte differentiation [GO:0010725]; semicircular canal development [GO:0060872]; somatic stem cell population maintenance [GO:0035019]; tissue development [GO:0009888]; urogenital system development [GO:0001655]; ventral spinal cord interneuron differentiation [GO:0021514] comp41188_c0_seq1,242,42.9752,0.81362996,0,9,,7.00E-20,Q9PB89,Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme),Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme),GO:0016208; GO:0005524; GO:0003987; GO:0019427; GO:0046872,AMP binding; ATP binding; acetate-CoA ligase activity; acetyl-CoA biosynthetic process from acetate; metal ion binding,PF16177;PF00501;PF13193;,4.00E-14,CHOYP_BRAFLDRAFT_59014.1.1,2.00E-33,ruditapes_c9865,,,,,ACSA_XYLFA,Xylella fastidiosa (strain 9a5c),acetyl-CoA biosynthetic process from acetate [GO:0019427] comp41189_c0_seq1,319,39.4984,0.48980073,8,9,,5.00E-06,Q5DU41,Leucine-rich repeat-containing protein 8B (T-cell activation leucine repeat-rich protein) (TA-LRRP),Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP),GO:0016021,integral to membrane,PF13855;PF12534;,,,,,,,,,LRC8B_MOUSE,Mus musculus (Mouse),anion transmembrane transport [GO:0098656] comp41244_c0_seq1,244,38.1148,1.02085048,6,13,,2.00E-12,Q9Y115,UNC93-like protein,UNC93-like protein,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF05978;,,,,,,,,,UN93L_DROME,Drosophila melanogaster (Fruit fly), comp41275_c0_seq1,277,58.1227,0.82429289,3,16,,7.00E-06,P09085,Homeotic protein caudal,Homeotic protein caudal,GO:0007443; GO:0000977; GO:0007487; GO:0009948; GO:0007350; GO:0005737; GO:0035224; GO:0007377; GO:0005634; GO:0002807; GO:0008284; GO:0045944; GO:0007379; GO:0003700; GO:0006351,"Malpighian tubule morphogenesis; RNA polymerase II regulatory region sequence-specific DNA binding; analia development; anterior/posterior axis specification; blastoderm segmentation; cytoplasm; genital disc anterior/posterior pattern formation; germ-band extension; nucleus; positive regulation of antimicrobial peptide biosynthetic process; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; segment specification; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;,8.00E-11,CHOYP_CDX1.1.1,,,,,,,CAD_DROME,Drosophila melanogaster (Fruit fly),"analia development [GO:0007487]; anterior/posterior axis specification [GO:0009948]; blastoderm segmentation [GO:0007350]; cell differentiation [GO:0030154]; gastrulation involving germ band extension [GO:0010004]; genital disc anterior/posterior pattern formation [GO:0035224]; genital disc development [GO:0035215]; germ-band extension [GO:0007377]; hindgut morphogenesis [GO:0007442]; Malpighian tubule morphogenesis [GO:0007443]; organ morphogenesis [GO:0009887]; positive regulation of antimicrobial peptide biosynthetic process [GO:0002807]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; transcription, DNA-templated [GO:0006351]" comp41286_c0_seq1,243,44.4444,0.43324597,5,3,,1.00E-19,Q9BVA6,Adenosine monophosphate-protein transferase FICD (EC 2.7.7.n1) (AMPylator FICD) (FIC domain-containing protein) (Huntingtin yeast partner E) (Huntingtin-interacting protein 13) (HIP-13) (Huntingtin-interacting protein E),Adenosine monophosphate-protein transferase FICD (EC 2.7.7.n1) (AMPylator FICD) (FIC domain-containing protein) (Huntingtin yeast partner E) (Huntingtin-interacting protein 13) (HIP-13) (Huntingtin-interacting protein E),GO:0005524; GO:0016021; GO:0034259; GO:0070733,ATP binding; integral to membrane; negative regulation of Rho GTPase activity; protein adenylyltransferase activity,PF02661;,,,,,,,,,FICD_HUMAN,Homo sapiens (Human),negative regulation of GTPase activity [GO:0034260]; protein adenylylation [GO:0018117] comp4130_c0_seq1,283,43.4629,0.45199503,8,0,,1.00E-38,O00750,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta),Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta),GO:0016303; GO:0035005; GO:0005524; GO:0030139; GO:0005783; GO:0043231; GO:0001727; GO:0005634; GO:0005942; GO:0035091; GO:0048015; GO:0005886; GO:0043491; GO:0044281,1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; endocytic vesicle; endoplasmic reticulum; intracellular membrane-bounded organelle; lipid kinase activity; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol binding; phosphatidylinositol-mediated signaling; plasma membrane; protein kinase B signaling cascade; small molecule metabolic process,PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;,1.00E-46,CHOYP_LOC100121969.1.1,,,,,,,P3C2B_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491] comp41322_c1_seq1,236,66.9492,1.04560701,0,10,,2.00E-48,Q6A6Y8,Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)],Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)],GO:0006189; GO:0003937; GO:0004643,'de novo' IMP biosynthetic process; IMP cyclohydrolase activity; phosphoribosylaminoimidazolecarboxamide formyltransferase activity,PF01808;PF02142;,,,,,,,,,PUR9_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' IMP biosynthetic process [GO:0006189] comp41356_c0_seq1,293,44.7099,0.34719346,8,0,,1.00E-06,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp41424_c0_seq1,408,46.8137,0.1797813,0,10,,7.00E-25,Q9QW07,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)",GO:0005509; GO:0005737; GO:0035556; GO:0016042; GO:0043267; GO:0004435; GO:0007602; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid catabolic process; negative regulation of potassium ion transport; phosphatidylinositol phospholipase C activity; phototransduction; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,2.00E-34,CHOYP_PLCB4.1.2,,,,,,,PLCB4_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602] comp41434_c0_seq1,226,45.5752,0.86247889,10,0,,2.00E-16,D3YXS5,Kinesin-like protein KLP6 (Kinesin-like protein 6),Kinesin-like protein KIF28P (Kinesin-like protein 6),GO:0005524; GO:0005871; GO:0003777; GO:0031966; GO:0007005; GO:0072384,ATP binding; kinesin complex; microtubule motor activity; mitochondrial membrane; mitochondrion organization; organelle transport along microtubule,PF00498;PF12423;PF00225;,1.00E-26,CHOYP_LOC100366906.1.1,,,,,,,KLP6_MOUSE,Mus musculus (Mouse),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] comp41441_c0_seq1,230,42.1739,0.49529238,1,5,,1.00E-15,A2RRU4,Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),GO:0012507; GO:0000139; GO:0032933; GO:0007568; GO:0008203; GO:0005789; GO:0016021; GO:0043231; GO:0043234,ER to Golgi transport vesicle membrane; Golgi membrane; SREBP signaling pathway; aging; cholesterol metabolic process; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bounded organelle; protein complex,PF12349;PF00400;,3.00E-33,CHOYP_BRAFLDRAFT_118545.2.2,,,,,,,SCAP_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cholesterol metabolic process [GO:0008203]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933] comp41469_c0_seq1,210,59.5238,0.98294154,0,13,,2.00E-18,Q829X3,UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A),UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A),GO:0005524; GO:0006200; GO:0043190; GO:0016887; GO:0003677; GO:0009432; GO:0005737; GO:0009381; GO:0009380; GO:0090305; GO:0006289; GO:0006810; GO:0008270,ATP binding; ATP catabolic process; ATP-binding cassette (ABC) transporter complex; ATPase activity; DNA binding; SOS response; cytoplasm; excinuclease ABC activity; excinuclease repair complex; nucleic acid phosphodiester bond hydrolysis; nucleotide-excision repair; transport; zinc ion binding,PF00005;,,,,,,,,,UVRA_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432] comp41502_c0_seq1,400,39,0.4620605,3,11,,3.00E-09,Q96JT2,Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein),Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,5.00E-22,CHOYP_BRAFLDRAFT_79652.1.1,,,,,,,S45A3_HUMAN,Homo sapiens (Human),positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glucose metabolic process [GO:0010907]; regulation of oligodendrocyte differentiation [GO:0048713]; sucrose transport [GO:0015770] comp4152_c0_seq1,209,41.6268,0.34616177,4,0,,1.00E-17,Q5R7A7,Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3),Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3),GO:0005524; GO:0007154; GO:0016023; GO:0005769; GO:0043066; GO:0035091; GO:0004674; GO:0055037,ATP binding; cell communication; cytoplasmic membrane-bounded vesicle; early endosome; negative regulation of apoptotic process; phosphatidylinositol binding; protein serine/threonine kinase activity; recycling endosome,PF00069;PF00433;PF00787;,6.00E-23,CHOYP_LOC100367908.1.2,,,,,,,SGK3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp41538_c0_seq1,212,43.3962,0.61120442,2,13,,1.00E-06,Q8CJH3,Plexin-B1,Plexin-B1,GO:0005887; GO:0005622; GO:0033689; GO:0048812; GO:0043931; GO:0032321; GO:0050772; GO:0014068; GO:0008360; GO:0051493; GO:0017154; GO:0002116; GO:1900220,integral to plasma membrane; intracellular; negative regulation of osteoblast proliferation; neuron projection morphogenesis; ossification involved in bone maturation; positive regulation of Rho GTPase activity; positive regulation of axonogenesis; positive regulation of phosphatidylinositol 3-kinase cascade; regulation of cell shape; regulation of cytoskeleton organization; semaphorin receptor activity; semaphorin receptor complex; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB1_MOUSE,Mus musculus (Mouse),axon extension [GO:0048675]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] comp41559_c0_seq1,226,44.2478,0.63586679,4,11,,8.00E-23,A5PJX7,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,,,,,,,,,S6A13_BOVIN,Bos taurus (Bovine),chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836] comp41565_c0_seq1,242,39.6694,0.9508858,0,15,,6.00E-32,Q55E31,Ras-related protein Rab-32B,Ras-related protein Rab-32B,GO:0005525; GO:0015031; GO:0007264,GTP binding; protein transport; small GTPase mediated signal transduction,PF00071;,7.00E-11,CHOYP_NEMVEDRAFT_V1G245354.1.1,1.00E-42,ruditapes_c12471,,,,,RB32B_DICDI,Dictyostelium discoideum (Slime mold),melanosome organization [GO:0032438]; small GTPase mediated signal transduction [GO:0007264] comp41570_c0_seq1,555,45.7658,0.41875489,14,0,,2.00E-07,Q14159,DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair),DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair),GO:0072757; GO:0072711; GO:0071479; GO:0000724; GO:0000228; GO:2000781; GO:0031334; GO:0010569; GO:0070202,cellular response to camptothecin; cellular response to hydroxyurea; cellular response to ionizing radiation; double-strand break repair via homologous recombination; nuclear chromosome; positive regulation of double-strand break repair; positive regulation of protein complex assembly; regulation of double-strand break repair via homologous recombination; regulation of establishment of protein localization to chromosome,PF14950;PF14951;,,,,,,,,,K0146_HUMAN,Homo sapiens (Human),cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of protein complex assembly [GO:0031334]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of establishment of protein localization to chromosome [GO:0070202] comp41573_c0_seq1,218,49.0826,0.31064483,2,0,,7.00E-19,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,6.00E-24,CHOYP_NBEL1.1.1,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp41577_c0_seq1,270,45.1852,0.66188154,0,11,,2.00E-24,Q9H1A4,Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),GO:0005680; GO:0031145; GO:0051301; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination,PF12859;,7.00E-24,CHOYP_APC1.3.3,,,,,,,APC1_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp41607_c0_seq1,212,38.6792,1.5244321,7,0,,1.00E-08,Q9GSL0,FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,,,,,,,,,FMRF_LOLOP,Doryteuthis opalescens (California market squid) (Loligo opalescens),neuropeptide signaling pathway [GO:0007218] comp41647_c0_seq1,248,44.7581,0.88987802,3,8,,1.00E-13,Q8N357,Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog),Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog),GO:0005794; GO:0016021; GO:0005765; GO:0005739; GO:1901029; GO:0005634; GO:0008284; GO:0006810,Golgi apparatus; integral to membrane; lysosomal membrane; mitochondrion; negative regulation of mitochondrial outer membrane permeabilization; nucleus; positive regulation of cell proliferation; transport,PF06027;,6.00E-24,CHOYP_BRAFLDRAFT_74627.1.1,,,,,,,CB018_HUMAN,Homo sapiens (Human),negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; positive regulation of cell proliferation [GO:0008284] comp41651_c0_seq1,221,49.3213,1.17338555,2,11,,3.00E-20,Q5RD71,Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase),GO:0005524; GO:0006000; GO:0004454,ATP binding; fructose metabolic process; ketohexokinase activity,PF00294;,,,,,,,,,KHK_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),fructose metabolic process [GO:0006000] comp41654_c0_seq1,230,42.6087,0.59307925,0,17,,4.00E-08,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,2.00E-11,CHOYP_HSPA12A.16.27,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp41673_c0_seq1,288,43.4028,1.06028532,0,10,,,,,,,,,4.00E-14,CHOYP_PHUM_PHUM041660.1.1,,,,,,,,, comp41684_c0_seq1,268,42.5373,0.91075445,4,15,,8.00E-20,P02712,Acetylcholine receptor subunit beta,Acetylcholine receptor subunit beta,GO:0004889; GO:0030054; GO:0016021; GO:0045211,acetylcholine-activated cation-selective channel activity; cell junction; integral to membrane; postsynaptic membrane,PF02931;PF02932;,,,,,,,,,ACHB_TORCA,Tetronarce californica (Pacific electric ray) (Torpedo californica), comp41727_c0_seq1,235,43.4043,0.37460996,1,2,,8.00E-07,D4A8G9,Zinc finger FYVE domain-containing protein 26,Zinc finger FYVE domain-containing protein 26,GO:0006281; GO:0005813; GO:0000910; GO:0005737; GO:0046872; GO:0030496; GO:0032266,DNA repair; centrosome; cytokinesis; cytoplasm; metal ion binding; midbody; phosphatidylinositol-3-phosphate binding,PF01363;,,,,,,,,,ZFY26_RAT,Rattus norvegicus (Rat),cytokinesis [GO:0000910]; double-strand break repair via homologous recombination [GO:0000724] comp41752_c0_seq1,393,39.6947,0.65634275,15,7,,5.00E-06,Q56R14,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_XENLA,Xenopus laevis (African clawed frog),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp4176_c0_seq1,430,39.3023,1.04552506,8,0,,3.00E-08,Q2R1Z5,Putative calmodulin-like protein 6,Putative calmodulin-like protein 6,GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CML6_ORYSJ,Oryza sativa subsp. japonica (Rice), comp41776_c0_seq1,307,43.3225,0.58113824,0,28,,1.00E-11,O43490,Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133),Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133),GO:0042805; GO:0016324; GO:0005903; GO:0060219; GO:0009986; GO:0005615; GO:0072139; GO:0072112; GO:0005887; GO:0031528; GO:0045494; GO:0042622; GO:0005886; GO:2000768; GO:0010842; GO:0032420,actinin binding; apical plasma membrane; brush border; camera-type eye photoreceptor cell differentiation; cell surface; extracellular space; glomerular parietal epithelial cell differentiation; glomerular visceral epithelial cell differentiation; integral to plasma membrane; microvillus membrane; photoreceptor cell maintenance; photoreceptor outer segment membrane; plasma membrane; positive regulation of nephron tubule epithelial cell differentiation; retina layer formation; stereocilium,PF05478;,,,,,,,,,PROM1_HUMAN,Homo sapiens (Human),camera-type eye photoreceptor cell differentiation [GO:0060219]; glomerular parietal epithelial cell differentiation [GO:0072139]; glomerular visceral epithelial cell differentiation [GO:0072112]; photoreceptor cell maintenance [GO:0045494]; positive regulation of nephron tubule epithelial cell differentiation [GO:2000768]; retina layer formation [GO:0010842]; retina morphogenesis in camera-type eye [GO:0060042] comp41792_c0_seq1,231,48.0519,1.33816495,2,0,,,,,,,,,4.00E-13,CHOYP_contig_002523,,,,,,,,, comp41798_c0_seq1,338,48.2249,0.89599665,7,35,,2.00E-13,Q9NRA2,Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),GO:0006865; GO:0030054; GO:0005887; GO:0005765; GO:0015136; GO:0015739; GO:0005351; GO:0030672,amino acid transport; cell junction; integral to plasma membrane; lysosomal membrane; sialic acid transmembrane transporter activity; sialic acid transport; sugar:hydrogen symporter activity; synaptic vesicle membrane,PF07690;,,,,,,,,,S17A5_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739] comp41800_c0_seq1,226,41.1504,0.84782239,3,11,,8.00E-35,Q6Q4G4,Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE),Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE),GO:0004180; GO:0005615; GO:0016020; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; extracellular space; membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,1.00E-51,CHOYP_ACE.3.4,,,,,,,ACE_THETS,Theromyzon tessulatum (Duck leech), comp41815_c0_seq1,313,45.3674,0.24915946,4,9,,1.00E-25,Q9H0R1,AP-5 complex subunit mu-1 (Adapter-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein),AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein),GO:0030119; GO:0030131; GO:0005829; GO:0016197; GO:0006886; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0016192,AP-type membrane coat adaptor complex; clathrin adaptor complex; cytosol; endosomal transport; intracellular protein transport; late endosome; late endosome membrane; lysosomal membrane; lysosome; vesicle-mediated transport,PF00928;,,,,,,,,,AP5M1_HUMAN,Homo sapiens (Human),endosomal transport [GO:0016197]; protein transport [GO:0015031] comp41819_c0_seq1,265,47.5472,0.53956144,9,3,,4.00E-33,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp41824_c0_seq1,221,38.914,0.48446164,5,0,,2.00E-11,Q9C8G9,ABC transporter C family member 1 (ABC transporter ABCC.1) (AtABCC1) (EC 3.6.3.44) (ATP-energized glutathione S-conjugate pump 1) (Glutathione S-conjugate-transporting ATPase 1) (Multidrug resistance-associated protein 1),ABC transporter C family member 1 (ABC transporter ABCC.1) (AtABCC1) (EC 3.6.3.44) (ATP-energized glutathione S-conjugate pump 1) (Glutathione S-conjugate-transporting ATPase 1) (Multidrug resistance-associated protein 1),GO:0005524; GO:0015700; GO:0015446; GO:0016021; GO:0071992; GO:0000325; GO:0009506; GO:0046685; GO:0005774; GO:0008559,ATP binding; arsenite transport; arsenite-transmembrane transporting ATPase activity; integral to membrane; phytochelatin transmembrane transporter activity; plant-type vacuole; plasmodesma; response to arsenic-containing substance; vacuolar membrane; xenobiotic-transporting ATPase activity,PF00664;PF00005;,,,,,,,,,AB1C_ARATH,Arabidopsis thaliana (Mouse-ear cress),(+)-abscisic acid D-glucopyranosyl ester transmembrane transport [GO:1902418]; arsenite transport [GO:0015700]; response to arsenic-containing substance [GO:0046685] comp41859_c0_seq1,235,40.8511,0.93200459,3,45,,3.00E-12,Q8NFP4,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,,,,,,,,,MDGA1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp41892_c0_seq1,217,48.3871,0.23904016,5,9,,7.00E-25,Q4KLQ5,WD repeat-containing protein 76,WD repeat-containing protein 76,,,,,,,,,,,,WDR76_XENLA,Xenopus laevis (African clawed frog),cellular response to DNA damage stimulus [GO:0006974] comp41955_c0_seq1,215,40,0.73304753,5,16,,,,,,,,,3.00E-46,CHOYP_BRAFLDRAFT_117315.2.2,,,,,,,,, comp41957_c0_seq1,209,44.0191,0.09929305,2,0,,9.00E-08,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp41979_c0_seq1,259,36.2934,1.07686833,0,6,,,,,,,,,,,4.00E-12,ruditapes_c8979,,,,,,, comp41989_c0_seq1,509,44.0079,0.51346788,18,16,,5.00E-37,Q11002,Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit],Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit],GO:0021919; GO:0015629; GO:0005509; GO:0004198; GO:0042335; GO:0005737; GO:0008340; GO:0043025; GO:0006909; GO:0016540; GO:0006508,BMP signaling pathway involved in spinal cord dorsal/ventral patterning; actin cytoskeleton; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cuticle development; cytoplasm; determination of adult lifespan; neuronal cell body; phagocytosis; protein autoprocessing; proteolysis,PF01067;PF00648;,4.00E-62,CHOYP_LOC100747565.2.2,,,,,,,CANA_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; BMP signaling pathway involved in spinal cord dorsal/ventral patterning [GO:0021919]; cuticle development [GO:0042335]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; dorsal/ventral pattern formation [GO:0009953]; phagocytosis [GO:0006909]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] comp41993_c0_seq1,252,51.5873,0.77865809,9,6,,5.00E-08,Q13183,Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),GO:0005887; GO:0015361,integral to plasma membrane; low affinity sodium:dicarboxylate symporter activity,PF00939;,7.00E-11,CHOYP_S13A5.1.2,,,,,,,S13A2_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp42004_c0_seq1,345,49.2754,1.05415648,7,10,,3.00E-45,Q5REG4,Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3),Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3),GO:0007219; GO:0005737; GO:0016874; GO:0016567; GO:0008270,Notch signaling pathway; cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,,7.00E-19,CHOYP_DTX3L.4.4,,,,,,,DTX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] comp42008_c0_seq1,379,45.9103,0.36220296,2,13,,3.00E-14,Q7TSH8,Uncharacterized protein KIAA0195,Transmembrane protein 94,GO:0016021,integral to membrane,,,,,,,,,,K0195_MOUSE,Mus musculus (Mouse), comp42008_c0_seq2,255,45.098,0.5513931,0,0,,,,,,,,,2.00E-12,CHOYP_LOC100123810.2.2,,,,,,,,, comp42012_c0_seq1,256,43.75,0.49423831,8,2,,6.00E-17,Q80YE7,Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),GO:0005524; GO:0015629; GO:0005516; GO:0004683; GO:0071346; GO:0005829; GO:0008625; GO:0007243; GO:0043066; GO:1902042; GO:0017148; GO:0046777; GO:0004672; GO:2000310,ATP binding; actin cytoskeleton; calmodulin binding; calmodulin-dependent protein kinase activity; cellular response to interferon-gamma; cytosol; extrinsic apoptotic signaling pathway via death domain receptors; intracellular protein kinase cascade; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of translation; protein autophosphorylation; protein kinase activity; regulation of N-methyl-D-aspartate selective glutamate receptor activity,PF12796;PF00531;PF00069;,,,,,,,,,DAPK1_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310] comp42021_c0_seq1,476,44.3277,0.83468779,1,39,,3.00E-10,O88277,Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1),GO:0005509; GO:0005913; GO:0010631; GO:0007156; GO:0016021; GO:0005634; GO:0005886,calcium ion binding; cell-cell adherens junction; epithelial cell migration; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT2_RAT,Rattus norvegicus (Rat),epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp42041_c0_seq1,248,39.9194,0.40853823,10,4,,7.00E-21,Q86UB9,Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52),Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52),GO:0016021; GO:0005777; GO:0007031,integral to membrane; peroxisome; peroxisome organization,PF02466;PF15982;,,,,,,,,,TM135_HUMAN,Homo sapiens (Human),peroxisome organization [GO:0007031] comp42044_c0_seq1,351,42.4501,0.64706408,6,9,,1.00E-17,Q8C0J2,Autophagy-related protein 16-1 (APG16-like 1),Autophagy-related protein 16-1 (APG16-like 1),GO:0000045; GO:0000421; GO:0034045; GO:0015031,autophagic vacuole assembly; autophagic vacuole membrane; pre-autophagosomal structure membrane; protein transport,PF08614;PF00400;,2.00E-20,CHOYP_BRAFLDRAFT_123636.1.1,,,,,,,A16L1_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; protein transport [GO:0015031] comp42059_c0_seq1,260,44.2308,0.4869475,2,9,,9.00E-23,O95045,Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3),Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3),GO:0044206; GO:0005829; GO:0009166; GO:0006206; GO:0046135; GO:0043097; GO:0045098; GO:0046108; GO:0004850,UMP salvage; cytosol; nucleotide catabolic process; pyrimidine nucleobase metabolic process; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; type III intermediate filament; uridine metabolic process; uridine phosphorylase activity,PF01048;,1.00E-21,CHOYP_LOC100646810.1.1,,,,,,,UPP2_HUMAN,Homo sapiens (Human),nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine metabolic process [GO:0046108] comp42104_c0_seq1,555,40.1802,1.00482254,3,75,,2.00E-42,Q76G19,PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein),PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein),GO:0005938,cell cortex,PF00595;,5.00E-74,CHOYP_PDZRN3.1.1,,,,,,,PDZD4_HUMAN,Homo sapiens (Human), comp42116_c0_seq1,435,44.5977,0.64901991,16,0,,8.00E-16,Q6VNB8,"WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)","WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)",GO:0005545; GO:0005776; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; autophagic vacuole; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,1.00E-24,CHOYP_BRAFLDRAFT_202950.1.1,,,,,,,WDFY3_MOUSE,Mus musculus (Mouse),aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239] comp42123_c0_seq1,511,43.0528,1.016297,7,17,,2.00E-27,P98187,Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8),Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8),GO:0018685; GO:0070330; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0006693; GO:0006805,alkane 1-monooxygenase activity; aromatase activity; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; prostaglandin metabolic process; xenobiotic metabolic process,PF00067;,,,,,,,,,CP4F8_HUMAN,Homo sapiens (Human),icosanoid metabolic process [GO:0006690]; prostaglandin metabolic process [GO:0006693] comp42138_c0_seq1,269,45.7249,0.52500726,1,5,,6.00E-42,Q5ZMA6,Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase),Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase),GO:0005524; GO:0009435; GO:0003952; GO:0016810,"ATP binding; NAD biosynthetic process; NAD+ synthase (glutamine-hydrolyzing) activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",PF00795;PF02540;,7.00E-56,CHOYP_NEMVEDRAFT_V1G173435.1.1,,,,,,,NADE_CHICK,Gallus gallus (Chicken),NAD biosynthetic process [GO:0009435] comp42145_c0_seq1,434,43.7788,0.48285305,1,56,,1.00E-08,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp42165_c0_seq1,283,46.2898,0.39832194,3,8,,6.00E-13,Q9NZM6,Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2),Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2),GO:0005262; GO:0005509; GO:0050982; GO:0016021,calcium channel activity; calcium ion binding; detection of mechanical stimulus; integral to membrane,PF08016;,,,,,,,,,PK2L2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982] comp42183_c0_seq1,477,46.9602,0.74108853,0,33,,2.00E-20,Q9P283,Semaphorin-5B,Semaphorin-5B,GO:0030154; GO:0016021; GO:0007399; GO:0004872,cell differentiation; integral to membrane; nervous system development; receptor activity,PF01437;PF01403;PF00090;,,,,,,,,,SEM5B_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; detection of light stimulus involved in visual perception [GO:0050908]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neuron projection guidance [GO:0097485]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526] comp42208_c0_seq1,386,42.487,0.46739444,3,0,,1.00E-33,P49327,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0070402; GO:0004313; GO:0004314; GO:0006084; GO:0071353; GO:0005829; GO:0008144; GO:0006112; GO:0047117; GO:0004319; GO:0006633; GO:0006631; GO:0004312; GO:0042587; GO:0035338; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0015939; GO:0005886; GO:0031325; GO:0019432; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; NADPH binding; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; acetyl-CoA metabolic process; cellular response to interleukin-4; cytosol; drug binding; energy reserve metabolic process; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; fatty acid metabolic process; fatty acid synthase activity; glycogen granule; long-chain fatty-acyl-CoA biosynthetic process; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; pantothenate metabolic process; plasma membrane; positive regulation of cellular metabolic process; triglyceride biosynthetic process; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,2.00E-21,CHOYP_FASN.3.4,,,,,,,FAS_HUMAN,Homo sapiens (Human),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]; pantothenate metabolic process [GO:0015939]; positive regulation of cellular metabolic process [GO:0031325] comp42219_c0_seq1,396,44.4444,1.07881123,10,0,,9.00E-16,P28570,Sodium- and chloride-dependent creatine transporter 1 (CHOT1) (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8),Sodium- and chloride-dependent creatine transporter 1 (CHOT1) (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8),GO:0015220; GO:0005309; GO:0005887; GO:0005328; GO:0005886,choline transmembrane transporter activity; creatine:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,,,,,,,,,SC6A8_RAT,Rattus norvegicus (Rat),creatine transport [GO:0015881]; embryonic brain development [GO:1990403] comp42231_c0_seq1,380,47.6316,0.47153792,2,17,,9.00E-24,P16960,Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor),Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor),GO:0005509; GO:0071313; GO:0016021; GO:0006936; GO:0043931; GO:0003151; GO:0014808; GO:0005219; GO:0033017; GO:0048741; GO:0043588; GO:0005245,calcium ion binding; cellular response to caffeine; integral to membrane; muscle contraction; ossification involved in bone maturation; outflow tract morphogenesis; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane; skeletal muscle fiber development; skin development; voltage-gated calcium channel activity,PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,8.00E-19,CHOYP_LOC100643070.1.1,,,,,,,RYR1_PIG,Sus scrofa (Pig),cellular response to caffeine [GO:0071313]; muscle contraction [GO:0006936]; ossification involved in bone maturation [GO:0043931]; outflow tract morphogenesis [GO:0003151]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; skeletal muscle fiber development [GO:0048741]; skin development [GO:0043588] comp42240_c0_seq1,338,46.1538,0.73206621,0,0,,3.00E-40,Q5RF24,WD repeat-containing protein 13,WD repeat-containing protein 13,GO:0005634,nucleus,PF00400;,1.00E-34,CHOYP_WDR13.1.1,,,,,,,WDR13_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp42240_c0_seq2,339,46.0177,0.73864279,0,0,,5.00E-06,Q5BK30,Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69),Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69),GO:0005929,cilium,PF00400;,,,,,,,,,WDR69_RAT,Rattus norvegicus (Rat),determination of left/right symmetry [GO:0007368]; heart development [GO:0007507] comp42273_c0_seq1,391,36.0614,0.9468661,6,6,,5.00E-46,P30279,G1/S-specific cyclin-D2,G1/S-specific cyclin-D2,GO:0007049; GO:0051301; GO:0000785; GO:0000307; GO:0005829; GO:0031965; GO:0005730; GO:0045737,cell cycle; cell division; chromatin; cyclin-dependent protein kinase holoenzyme complex; cytosol; nuclear membrane; nucleolus; positive regulation of cyclin-dependent protein kinase activity,PF02984;PF00134;,,,3.00E-29,ruditapes_c29368,,,,,CCND2_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of protein phosphorylation [GO:0001934] comp42282_c0_seq1,467,40.0428,0.53571674,30,0,,,,,,,,,2.00E-33,CHOYP_CHGG_05501.1.1,,,,,,,,, comp42284_c0_seq1,240,47.0833,0.75787479,5,4,,6.00E-08,A0JNW5,UHRF1-binding protein 1-like,UHRF1-binding protein 1-like,,,PF12624;,,,,,,,,,UH1BL_HUMAN,Homo sapiens (Human), comp42291_c0_seq1,371,43.3962,0.63699093,20,0,,2.00E-40,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,1.00E-59,CHOYP_RN213.1.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp42315_c0_seq1,286,47.2028,0.69599616,8,13,,2.00E-06,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp42413_c0_seq1,494,50,0.68244765,22,0,,,,,,,,,2.00E-15,CHOYP_PHUM_PHUM244880.2.2,,,,,,,,, comp4242_c0_seq1,248,41.129,0.67013777,7,0,,1.00E-10,Q9GV77,Extracellular matrix protein 3 (FREM2 homolog),Extracellular matrix protein 3 (FREM2 homolog),GO:0005509; GO:0007154; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; cell communication; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF03160;,,,,,,,,,FREM2_LYTVA,Lytechinus variegatus (Green sea urchin) (Variegated urchin),cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp42440_c0_seq1,231,40.2597,0.32830804,10,6,,1.00E-10,Q6IV77,Tafazzin,Tafazzin,GO:0016021; GO:0016746,"integral to membrane; transferase activity, transferring acyl groups",PF01553;,,,,,,,,,TAZ_MACMU,Macaca mulatta (Rhesus macaque),cardiolipin acyl-chain remodeling [GO:0035965]; heart development [GO:0007507]; inner mitochondrial membrane organization [GO:0007007] comp42450_c0_seq1,311,42.1222,0.36414942,16,3,,2.00E-39,Q8N6T7,NAD-dependent protein deacetylase sirtuin-6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6),NAD-dependent protein deacetylase sirtuin-6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6),GO:0003956; GO:0003950; GO:0070403; GO:0046969; GO:0005724; GO:0005654; GO:0006471; GO:0010569; GO:0008270,NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity (H3-K9 specific); nuclear telomeric heterochromatin; nucleoplasm; protein ADP-ribosylation; regulation of double-strand break repair via homologous recombination; zinc ion binding,PF02146;,,,,,,,,,SIR6_HUMAN,Homo sapiens (Human),"base-excision repair [GO:0006284]; glucose homeostasis [GO:0042593]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of stem cell proliferation [GO:2000648]; post-embryonic cardiac muscle cell growth involved in heart morphogenesis [GO:0003247]; protein ADP-ribosylation [GO:0006471]; protein destabilization [GO:0031648]; regulation of double-strand break repair via homologous recombination [GO:0010569]; response to nutrient levels [GO:0031667]" comp42469_c0_seq1,236,48.3051,0.44107492,8,5,,4.00E-14,P42694,Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein),Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein),GO:0005524; GO:0004386; GO:0046872; GO:0005634,ATP binding; helicase activity; metal ion binding; nucleus,PF00642;,3.00E-15,CHOYP_HELZ.2.2,,,,,,,HELZ_HUMAN,Homo sapiens (Human), comp42499_c0_seq1,552,40.2174,0.27070334,14,7,,3.00E-43,Q08BG1,Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-),Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-),GO:0016787; GO:0016021; GO:0046872,hydrolase activity; integral to membrane; metal ion binding,PF00149;,,,,,,,,,TMPPE_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp42547_c0_seq1,732,31.694,0.3878021,30,13,,2.00E-34,O14662,Syntaxin-16 (Syn16),Syntaxin-16 (Syn16),GO:0005794; GO:0000139; GO:0005484; GO:0031201; GO:0016021; GO:0006891; GO:0006886; GO:0005730; GO:0042147,"Golgi apparatus; Golgi membrane; SNAP receptor activity; SNARE complex; integral to membrane; intra-Golgi vesicle-mediated transport; intracellular protein transport; nucleolus; retrograde transport, endosome to Golgi",PF05739;PF00804;,1.00E-20,CHOYP_LOC100372071.1.1,,,,,,,STX16_HUMAN,Homo sapiens (Human),"Golgi ribbon formation [GO:0090161]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]" comp42602_c1_seq1,228,45.1754,0.69871672,2,10,,3.00E-25,Q07071,Glucokinase regulatory protein (Glucokinase regulator),Glucokinase regulatory protein (Glucokinase regulator),GO:0030246; GO:0001678; GO:0005829; GO:0051594; GO:0019899; GO:0004857; GO:0070095; GO:0006006; GO:0005739; GO:0033132; GO:0005654; GO:0033133; GO:0000060; GO:0009750,"carbohydrate binding; cellular glucose homeostasis; cytosol; detection of glucose; enzyme binding; enzyme inhibitor activity; fructose-6-phosphate binding; glucose metabolic process; mitochondrion; negative regulation of glucokinase activity; nucleoplasm; positive regulation of glucokinase activity; protein import into nucleus, translocation; response to fructose stimulus",,,,,,,,,,GCKR_RAT,Rattus norvegicus (Rat),"cellular glucose homeostasis [GO:0001678]; detection of glucose [GO:0051594]; glucose metabolic process [GO:0006006]; negative regulation of catalytic activity [GO:0043086]; negative regulation of glucokinase activity [GO:0033132]; positive regulation of glucokinase activity [GO:0033133]; protein import into nucleus, translocation [GO:0000060]; response to fructose [GO:0009750]" comp42613_c1_seq1,272,45.2206,0.87594767,3,6,,8.00E-26,Q99MD8,Myoneurin,Myoneurin,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,MYNN_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp42623_c0_seq1,252,40.4762,0.68116457,4,8,,1.00E-42,Q5ZKN1,Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9),Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9),GO:0005524; GO:0016605; GO:0008353; GO:0071345; GO:0004693; GO:0071157; GO:0008024; GO:0006282; GO:0031056; GO:0006355; GO:0043111; GO:0044212; GO:0006351,"ATP binding; PML body; RNA polymerase II carboxy-terminal domain kinase activity; cellular response to cytokine stimulus; cyclin-dependent protein serine/threonine kinase activity; negative regulation of cell cycle arrest; positive transcription elongation factor complex b; regulation of DNA repair; regulation of histone modification; regulation of transcription, DNA-dependent; replication fork arrest; transcription regulatory region DNA binding; transcription, DNA-dependent",PF00069;,,,,,,,,,CDK9_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp42727_c0_seq1,466,48.927,0.4707683,7,11,,9.00E-21,A0JP70,WD repeat-containing protein 90,WD repeat-containing protein 90,,,PF05018;PF00400;,,,,,,,,,WDR90_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp42737_c0_seq1,238,41.1765,0.5150953,6,2,,8.00E-16,Q9GZV3,High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7),High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7),GO:0008292; GO:0008219; GO:0033265; GO:0005307; GO:0016021; GO:0007274; GO:0043025; GO:0007269; GO:0005886; GO:0007271,"acetylcholine biosynthetic process; cell death; choline binding; choline:sodium symporter activity; integral to membrane; neuromuscular synaptic transmission; neuronal cell body; neurotransmitter secretion; plasma membrane; synaptic transmission, cholinergic",PF00474;,2.00E-12,CHOYP_BRAFLDRAFT_207989.1.1,,,,,,,SC5A7_HUMAN,Homo sapiens (Human),"acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; synaptic transmission, cholinergic [GO:0007271]; transmembrane transport [GO:0055085]" comp42746_c0_seq1,483,38.5093,0.67277017,18,36,,1.00E-31,Q5U2Z7,Rho GTPase-activating protein 24 (Down-regulated in nephrectomized rat kidney #2) (Rho-type GTPase-activating protein 24),Rho GTPase-activating protein 24 (Down-regulated in nephrectomized rat kidney #2) (Rho-type GTPase-activating protein 24),GO:0005096; GO:0001525; GO:0030154; GO:0042995; GO:0005737; GO:0005856; GO:0005925; GO:0005543; GO:0005886; GO:0043547; GO:0007165,GTPase activator activity; angiogenesis; cell differentiation; cell projection; cytoplasm; cytoskeleton; focal adhesion; phospholipid binding; plasma membrane; positive regulation of GTPase activity; signal transduction,PF00169;PF00620;,2.00E-15,CHOYP_RHG24.1.2,,,,,,,RHG24_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; signal transduction [GO:0007165] comp42764_c0_seq1,459,42.4837,0.39715276,17,8,,1.00E-09,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,4.00E-17,CHOYP_LOC658092.2.2,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp42775_c0_seq1,231,66.6667,1.02014427,0,11,,6.00E-11,P30177,Uncharacterized protein YbiB,Uncharacterized protein YbiB,GO:0016757,"transferase activity, transferring glycosyl groups",PF02885;,,,,,,,,,YBIB_ECOLI,Escherichia coli (strain K12),metabolic process [GO:0008152] comp42844_c0_seq1,453,39.7351,0.34050166,8,25,,4.00E-16,Q3UY23,Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1),Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1),GO:0005524; GO:0000287; GO:0004826; GO:0006432; GO:0000049; GO:0008033,ATP binding; magnesium ion binding; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding; tRNA processing,PF10354;PF03147;,,,,,,,,,FDXA1_MOUSE,Mus musculus (Mouse),rRNA base methylation [GO:0070475]; tRNA processing [GO:0008033] comp42861_c0_seq1,417,40.7674,0.23257889,21,0,,,,,,,,,1.00E-11,CHOYP_BRAFLDRAFT_80394.5.9,,,,,,,,, comp42915_c0_seq1,218,43.1193,0.50695511,1,22,,6.00E-06,P22105,Tenascin-X (TN-X) (Hexabrachion-like protein),Tenascin-X (TN-X) (Hexabrachion-like protein),GO:0030036; GO:0007155; GO:0016337; GO:0007160; GO:0030199; GO:0032963; GO:0048251; GO:0043206; GO:0005615; GO:0006631; GO:0008201; GO:0005178; GO:0005622; GO:0005578; GO:0043506; GO:0006641,actin cytoskeleton organization; cell adhesion; cell-cell adhesion; cell-matrix adhesion; collagen fibril organization; collagen metabolic process; elastic fiber assembly; extracellular fibril organization; extracellular space; fatty acid metabolic process; heparin binding; integrin binding; intracellular; proteinaceous extracellular matrix; regulation of JUN kinase activity; triglyceride metabolic process,PF07974;PF00147;PF00041;PF12661;,,,,,,,,,TENX_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; fatty acid metabolic process [GO:0006631]; regulation of JUN kinase activity [GO:0043506]; single organismal cell-cell adhesion [GO:0016337]; triglyceride metabolic process [GO:0006641] comp42934_c0_seq1,495,38.7879,0.43285875,23,4,,8.00E-41,Q9EQG7,Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-),Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-),GO:0007154; GO:0005576; GO:0005887; GO:0009166; GO:0004551,cell communication; extracellular region; integral to plasma membrane; nucleotide catabolic process; nucleotide diphosphatase activity,PF01663;,6.00E-22,CHOYP_BRAFLDRAFT_85509.1.1,,,,,,,ENPP5_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; nucleotide catabolic process [GO:0009166] comp42943_c0_seq1,510,43.1373,0.72518853,5,23,,2.00E-67,Q08201,Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (Multidrug resistance protein 2) (P-glycoprotein 2) (P-glycoprotein 3),Phosphatidylcholine translocator ABCB4 (ATP-binding cassette sub-family B member 4) (Multidrug resistance protein 2) (Multidrug resistance protein 3) (EC 3.6.3.44) (P-glycoprotein 2) (P-glycoprotein 3),GO:0005524; GO:0042626; GO:0000139; GO:0016324; GO:0016021; GO:0046581; GO:0042493; GO:0051384; GO:0008559,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; Golgi membrane; apical plasma membrane; integral to membrane; intercellular canaliculus; response to drug; response to glucocorticoid stimulus; xenobiotic-transporting ATPase activity",PF00664;PF00005;,1.00E-36,CHOYP_LOC582726.1.1,2.00E-26,ruditapes_c26195,,,,,MDR3_RAT,Rattus norvegicus (Rat),"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; bile acid secretion [GO:0032782]; cellular response to bile acid [GO:1903413]; lipid homeostasis [GO:0055088]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of phospholipid translocation [GO:0061092]; positive regulation of phospholipid transport [GO:2001140]; response to drug [GO:0042493]; response to fenofibrate [GO:1901557]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]" comp42948_c0_seq2,1119,51.832,1.25376833,41,31,,4.00E-111,Q9ET80,Junctophilin-1 (JP-1) (Junctophilin type 1),Junctophilin-1 (JP-1) (Junctophilin type 1),GO:0030018; GO:0016021; GO:0030314; GO:0014701; GO:0007517; GO:0005886; GO:0008307,Z disc; integral to membrane; junctional membrane complex; junctional sarcoplasmic reticulum membrane; muscle organ development; plasma membrane; structural constituent of muscle,PF02493;,4.00E-168,CHOYP_LOC662408.1.1,,,,,,,JPH1_MOUSE,Mus musculus (Mouse),muscle organ development [GO:0007517] comp42984_c0_seq1,243,45.679,0.16431255,1,17,,9.00E-11,A2RT67,DENN domain-containing protein 3,DENN domain-containing protein 3,GO:0017112; GO:0044257; GO:0008333,Rab guanyl-nucleotide exchange factor activity; cellular protein catabolic process; endosome to lysosome transport,PF02141;,,,,,,,,,DEND3_MOUSE,Mus musculus (Mouse),cellular protein catabolic process [GO:0044257]; endosome to lysosome transport [GO:0008333] comp42989_c0_seq1,352,40.9091,0.47897266,9,13,,,,,,,,,3.00E-18,CHOYP_RN123.1.2,,,,,,,,, comp43002_c0_seq2,363,44.0771,0.62572752,2,0,,2.00E-19,Q9Y6X6,Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16),Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16),GO:0005524; GO:0051015; GO:0021549; GO:0005829; GO:0003774; GO:0016459; GO:2000134; GO:0008285; GO:0048812; GO:0005730; GO:0005654; GO:0048471; GO:0014065; GO:0005886,ATP binding; actin filament binding; cerebellum development; cytosol; motor activity; myosin complex; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell proliferation; neuron projection morphogenesis; nucleolus; nucleoplasm; perinuclear region of cytoplasm; phosphatidylinositol 3-kinase cascade; plasma membrane,PF12796;PF00063;,,,,,,,,,MYO16_HUMAN,Homo sapiens (Human),cerebellum development [GO:0021549]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134] comp43047_c0_seq1,206,46.1165,0.82655009,0,5,,2.00E-13,P42891,Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),GO:0016021; GO:0016020; GO:0046872; GO:0004222; GO:0016486; GO:0005886; GO:0006508,integral to membrane; membrane; metal ion binding; metalloendopeptidase activity; peptide hormone processing; plasma membrane; proteolysis,PF01431;PF05649;,4.00E-13,CHOYP_ECE2.1.1,,,,,,,ECE1_BOVIN,Bos taurus (Bovine),peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; proteolysis [GO:0006508] comp43062_c0_seq1,451,38.5809,0.83881643,23,4,,7.00E-09,Q8IZJ3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,GO:0005615; GO:0010951; GO:0005886; GO:0004867,extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;,,,,,,,,,CPMD8_HUMAN,Homo sapiens (Human), comp43077_c0_seq1,232,50,0.7766811,0,15,,8.00E-14,Q9VVE5,RNA-binding protein Musashi homolog Rbp6,RNA-binding protein Musashi homolog Rbp6,GO:0005737; GO:0000166; GO:0008266; GO:0005844; GO:0048864,cytoplasm; nucleotide binding; poly(U) RNA binding; polysome; stem cell development,PF00076;,7.00E-17,CHOYP_RBP6.2.2,,,,,,,MSIR6_DROME,Drosophila melanogaster (Fruit fly),stem cell development [GO:0048864] comp43168_c0_seq1,223,42.6009,0.30352914,0,19,,2.00E-11,Q642A7,Protein FAM151A,Protein FAM151A,GO:0016021,integral to membrane,PF10223;,,,,,,,,,F151A_RAT,Rattus norvegicus (Rat), comp43171_c0_seq1,285,42.4561,0.86955189,2,10,,,,,,,,,7.00E-12,CHOYP_LOC100376472.1.1,,,,,,,,, comp43258_c0_seq1,264,39.0152,0.61248953,7,13,,2.00E-15,Q5R6R6,Poly(A)-specific ribonuclease PARN-like domain-containing protein 1,Poly(A)-specific ribonuclease PARN-like domain-containing protein 1,GO:0016021; GO:0003676; GO:0005634,integral to membrane; nucleic acid binding; nucleus,PF04857;,,,,,,,,,PNDC1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp43311_c0_seq2,406,37.1921,0.64286104,12,0,,3.00E-12,Q96MZ0,Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1-L1),Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1-L1),,,PF13417;,,,,,,,,,GD1L1_HUMAN,Homo sapiens (Human),glutathione metabolic process [GO:0006749] comp43312_c0_seq1,277,37.5451,0.72075013,1,0,,6.00E-10,Q5I0I9,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial","Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",GO:0005743,mitochondrial inner membrane,PF03364;,,,,,,,,,CQ10B_RAT,Rattus norvegicus (Rat), comp43317_c0_seq1,447,44.0716,0.69278697,25,0,,1.00E-38,Q8WPJ2,"Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)","Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)",GO:0046355; GO:0016985,"mannan catabolic process; mannan endo-1,4-beta-mannosidase activity",PF00150;,,,8.00E-30,ruditapes_c18590,,,,,MANA_MYTED,Mytilus edulis (Blue mussel),mannan catabolic process [GO:0046355] comp43324_c0_seq1,352,41.7614,0.8312469,2,19,,2.00E-09,A2VE15,Fatty acid desaturase 6 (EC 1.14.19.-),Fatty acid desaturase 6 (EC 1.14.19.-),GO:0006633; GO:0016021; GO:0016491,fatty acid biosynthetic process; integral to membrane; oxidoreductase activity,PF00487;,,,,,,,,,FADS6_BOVIN,Bos taurus (Bovine),fatty acid biosynthetic process [GO:0006633] comp43342_c0_seq1,260,48.0769,0.88131174,12,4,,5.00E-11,Q6ZQ12,Ninein-like protein,Ninein-like protein,GO:0005509; GO:0005737; GO:0005874; GO:0005815,calcium ion binding; cytoplasm; microtubule; microtubule organizing center,PF13499;,,,,,,,,,NINL_MOUSE,Mus musculus (Mouse),microtubule cytoskeleton organization [GO:0000226] comp43347_c0_seq1,349,47.851,0.35292713,18,0,,3.00E-08,Q6PQD5,Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog),GO:0016303; GO:0005524; GO:0003677; GO:0006281; GO:0016023; GO:0071044; GO:0007094; GO:0005634; GO:0002331; GO:0047485; GO:0004674; GO:0010212; GO:0005840; GO:0003735; GO:0006412,1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA repair; cytoplasmic membrane-bounded vesicle; histone mRNA catabolic process; mitotic spindle assembly checkpoint; nucleus; pre-B cell allelic exclusion; protein N-terminus binding; protein serine/threonine kinase activity; response to ionizing radiation; ribosome; structural constituent of ribosome; translation,PF02259;PF02260;PF00454;PF11640;,,,,,,,,,ATM_PIG,Sus scrofa (Pig),DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; mitotic spindle assembly checkpoint [GO:0007094]; pre-B cell allelic exclusion [GO:0002331]; replicative senescence [GO:0090399]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; translation [GO:0006412] comp43353_c0_seq1,468,44.2308,0.39515252,17,14,,4.00E-23,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-35,CHOYP_DNAH5.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp43356_c0_seq1,522,48.8506,0.55409651,17,12,,9.00E-32,Q9NVP4,Double zinc ribbon and ankyrin repeat-containing protein 1,Double zinc ribbon and ankyrin repeat-containing protein 1,GO:0008270,zinc ion binding,PF12773;PF13287;,,,,,,,,,DZAN1_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779] comp43402_c0_seq1,312,40.0641,0.48327825,5,11,,1.00E-08,Q5RDQ6,Zinc finger protein 507,Zinc finger protein 507,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN507_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp43422_c0_seq2,264,66.2879,0.83138448,0,11,,1.00E-06,Q9UT61,Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase),Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase),GO:0004559; GO:0030246; GO:0005829; GO:0000329; GO:0006013; GO:0009313; GO:0008270,alpha-mannosidase activity; carbohydrate binding; cytosol; fungal-type vacuole membrane; mannose metabolic process; oligosaccharide catabolic process; zinc ion binding,PF09261;PF01074;PF07748;,,,,,,,,,MAN1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517] comp43441_c0_seq1,229,61.5721,1.49353497,0,12,,2.00E-16,Q8XV41,Thiol:disulfide interchange protein DsbD (EC 1.8.1.8) (Protein-disulfide reductase) (Disulfide reductase),Thiol:disulfide interchange protein DsbD (EC 1.8.1.8) (Protein-disulfide reductase) (Disulfide reductase),GO:0045454; GO:0017004; GO:0009055; GO:0016021; GO:0005886; GO:0047134,cell redox homeostasis; cytochrome complex assembly; electron carrier activity; integral to membrane; plasma membrane; protein-disulfide reductase activity,PF11412;PF02683;,,,,,,,,,DSBD_RALSO,Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum),cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004] comp43464_c0_seq1,206,34.9515,0.6433718,0,0,,,,,,,,,2.00E-11,CHOYP_contig_019843,,,,,,,,, comp43464_c0_seq2,336,33.9286,0.52006633,11,4,,,,,,,,,6.00E-13,CHOYP_contig_032932,,,,,,,,, comp43473_c0_seq1,270,41.1111,0.97165609,20,0,,1.00E-18,A5PJX7,Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13),GO:0005332; GO:0005887; GO:0005328,gamma-aminobutyric acid:sodium symporter activity; integral to plasma membrane; neurotransmitter:sodium symporter activity,PF00209;,2.00E-12,CHOYP_SC6A5.4.7,,,,,,,S6A13_BOVIN,Bos taurus (Bovine),chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836] comp43476_c0_seq1,208,42.7885,0.95098255,1,6,,7.00E-09,Q6DDL7,Protein unc-93 homolog A (Unc-93A),Protein unc-93 homolog A (Unc-93A),GO:0016021,integral to membrane,PF05978;,,,,,,,,,UN93A_XENLA,Xenopus laevis (African clawed frog), comp434_c0_seq1,276,43.4783,0.77722681,7,0,,8.00E-10,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp43526_c0_seq1,260,43.8462,0.72860879,11,8,,5.00E-09,Q9VEG6,Chorion peroxidase (EC 1.11.1.7) (Peroxinectin-related protein) (Dpxt),Chorion peroxidase (EC 1.11.1.7) (Peroxinectin-related protein) (Dpxt),GO:0007306; GO:0005615; GO:0020037; GO:0042744; GO:0042743; GO:0046872; GO:0005875; GO:0004601; GO:0001516; GO:0004666,eggshell chorion assembly; extracellular space; heme binding; hydrogen peroxide catabolic process; hydrogen peroxide metabolic process; metal ion binding; microtubule associated complex; peroxidase activity; prostaglandin biosynthetic process; prostaglandin-endoperoxide synthase activity,PF03098;,,,,,,,,,PERC_DROME,Drosophila melanogaster (Fruit fly),chorion-containing eggshell formation [GO:0007304]; eggshell chorion assembly [GO:0007306]; hydrogen peroxide catabolic process [GO:0042744]; hydrogen peroxide metabolic process [GO:0042743]; ovarian follicle cell development [GO:0030707]; prostaglandin biosynthetic process [GO:0001516]; response to oxidative stress [GO:0006979] comp43529_c0_seq1,222,44.1441,0.37151941,2,9,,4.00E-10,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,1.00E-26,CHOYP_BRAFLDRAFT_128562.1.4,9.00E-32,ruditapes_c13734,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp43571_c0_seq1,330,40,1.06997057,14,13,,5.00E-08,Q32KY0,Apolipoprotein D (Apo-D) (ApoD),Apolipoprotein D (Apo-D) (ApoD),GO:0007568; GO:0007420; GO:0015485; GO:0022626; GO:0030425; GO:0005783; GO:0005615; GO:0006006; GO:0006629; GO:2000405; GO:1900016; GO:0051895; GO:0060588; GO:0071638; GO:0010642; GO:0042308; GO:0048662; GO:2000098; GO:0043025; GO:0048471; GO:0014012; GO:0042493; GO:0000302; GO:0042246; GO:0005215,aging; brain development; cholesterol binding; cytosolic ribosome; dendrite; endoplasmic reticulum; extracellular space; glucose metabolic process; lipid metabolic process; negative regulation of T cell migration; negative regulation of cytokine production involved in inflammatory response; negative regulation of focal adhesion assembly; negative regulation of lipoprotein lipid oxidation; negative regulation of monocyte chemotactic protein-1 production; negative regulation of platelet-derived growth factor receptor signaling pathway; negative regulation of protein import into nucleus; negative regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell-matrix adhesion; neuronal cell body; perinuclear region of cytoplasm; peripheral nervous system axon regeneration; response to drug; response to reactive oxygen species; tissue regeneration; transporter activity,PF08212;,,,,,,,,,APOD_BOVIN,Bos taurus (Bovine),aging [GO:0007568]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246] comp43577_c0_seq1,213,46.9484,0.68591255,7,0,,3.00E-13,Q6X893,Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92),Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92),GO:0015220; GO:0016021; GO:0005741; GO:0005886,choline transmembrane transporter activity; integral to membrane; mitochondrial outer membrane; plasma membrane,PF04515;,2.00E-24,CHOYP_BRAFLDRAFT_130395.1.1,,,,,,,CTL1_MOUSE,Mus musculus (Mouse),choline transport [GO:0015871] comp43662_c0_seq1,628,47.1338,0.31624012,27,6,,3.00E-36,Q5PR68,Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46),Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46),GO:0005813; GO:0005737,centrosome; cytoplasm,PF14846;,6.00E-42,CHOYP_CE112.2.2,,,,,,,CE112_MOUSE,Mus musculus (Mouse),receptor localization to synapse [GO:0097120] comp43671_c0_seq1,239,43.9331,0.43637128,0,13,,9.00E-21,Q6TUI4,Endoribonuclease Dicer (EC 3.1.26.-),Endoribonuclease Dicer (EC 3.1.26.3),GO:0005524; GO:0008026; GO:0016442; GO:0003723; GO:0005737; GO:0046872; GO:0090305; GO:0031054; GO:0030422; GO:0004525; GO:0030423,ATP binding; ATP-dependent helicase activity; RISC complex; RNA binding; cytoplasm; metal ion binding; nucleic acid phosphodiester bond hydrolysis; pre-miRNA processing; production of siRNA involved in RNA interference; ribonuclease III activity; targeting of mRNA for destruction involved in RNA interference,PF00270;PF03368;PF00271;PF02170;PF00636;,3.00E-21,CHOYP_BRAFLDRAFT_202604.1.1,,,,,,,DICER_BOVIN,Bos taurus (Bovine),apoptotic DNA fragmentation [GO:0006309]; pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423] comp43817_c0_seq1,289,42.5606,0.38400884,13,9,,3.00E-17,P0C0T2,Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6),Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6),GO:0005737; GO:0042803,cytoplasm; protein homodimerization activity,PF12796;PF13606;PF00536;,2.00E-30,CHOYP_LOC100378344.1.1,,,,,,,ANKS6_RAT,Rattus norvegicus (Rat), comp43817_c1_seq1,211,51.1848,1.01785551,3,0,,9.00E-06,Q8IV38,Ankyrin repeat and MYND domain-containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,GO:0005929; GO:0046872,cilium; metal ion binding,PF12796;PF01753;,,,,,,,,,ANKY2_HUMAN,Homo sapiens (Human), comp43826_c0_seq1,448,39.2857,0.81435825,9,11,,3.00E-15,Q2TGI5,Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Membrane-associated zinc finger protein DHHC25) (Zinc finger DHHC domain-containing protein 24) (DHHC-24),Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Membrane-associated zinc finger protein DHHC25) (Zinc finger DHHC domain-containing protein 24) (DHHC-24),GO:0016021; GO:0016746; GO:0008270,"integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDH24_RAT,Rattus norvegicus (Rat), comp43835_c0_seq1,286,43.007,0.38513622,2,20,,2.00E-11,Q9QXE5,Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16),Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16),GO:0016023; GO:0005768; GO:0005764; GO:0006508; GO:0008236,cytoplasmic membrane-bounded vesicle; endosome; lysosome; proteolysis; serine-type peptidase activity,PF05577;,,,,,,,,,TSSP_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp43938_c0_seq1,249,43.3735,1.05821813,4,6,,2.00E-14,O43548,Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5),Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5),GO:0006464; GO:0005737; GO:0008544; GO:0046872; GO:0018149; GO:0003810,cellular protein modification process; cytoplasm; epidermis development; metal ion binding; peptide cross-linking; protein-glutamine gamma-glutamyltransferase activity,PF00927;PF01841;PF00868;,,,,,,,,,TGM5_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; epidermis development [GO:0008544]; peptide cross-linking [GO:0018149] comp43950_c0_seq1,238,44.1176,0.26016424,2,0,,9.00E-14,Q08890,Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase),Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase),GO:0004423; GO:0005764; GO:0046872; GO:0008484,iduronate-2-sulfatase activity; lysosome; metal ion binding; sulfuric ester hydrolase activity,PF00884;,2.00E-17,CHOYP_LOC100185385.1.1,,,,,,,IDS_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp43984_c0_seq1,254,40.5512,0.48077668,11,0,,4.00E-20,Q6GQU2,Kelch-like protein 23,Kelch-like protein 23,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH23_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp43991_c0_seq1,268,45.8955,0.78489156,2,11,,5.00E-26,Q54G06,"Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)","Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)",GO:0010815; GO:0005737; GO:0030145; GO:0070006; GO:0006508,bradykinin catabolic process; cytoplasm; manganese ion binding; metalloaminopeptidase activity; proteolysis,PF01321;PF00557;PF16188;,,,,,,,,,XPP1_DICDI,Dictyostelium discoideum (Slime mold),bradykinin catabolic process [GO:0010815] comp43996_c0_seq1,280,38.5714,0.68970024,4,0,,2.00E-46,Q2KHT3,Protein CLEC16A,Protein CLEC16A (C-type lectin domain family 16 member A),,,PF09758;,3.00E-41,CHOYP_LOC410511.1.2,,,,,,,CL16A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914] comp44009_c0_seq1,324,42.284,0.97850394,4,33,,2.00E-06,Q13349,Integrin alpha-D (ADB2) (CD11 antigen-like family member D) (Leukointegrin alpha D) (CD antigen CD11d),Integrin alpha-D (ADB2) (CD11 antigen-like family member D) (Leukointegrin alpha D) (CD antigen CD11d),GO:0050798; GO:0016337; GO:0007160; GO:0006955; GO:0008305; GO:0007229; GO:0046872,activated T cell proliferation; cell-cell adhesion; cell-matrix adhesion; immune response; integrin complex; integrin-mediated signaling pathway; metal ion binding,PF01839;PF00357;PF08441;PF00092;,,,,,,,,,ITAD_HUMAN,Homo sapiens (Human),extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229] comp44052_c0_seq1,406,33.9901,1.22802469,12,3,,6.00E-07,Q4FE47,Putative E3 ubiquitin-protein ligase XBAT35 (EC 6.3.2.-) (Ankyrin repeat domain and RING finger-containing protein XBAT35) (Protein XB3 homolog 5),Putative E3 ubiquitin-protein ligase XBAT35 (EC 6.3.2.-) (Ankyrin repeat domain and RING finger-containing protein XBAT35) (Protein XB3 homolog 5),GO:0005737; GO:0005634; GO:0004842; GO:0008270,cytoplasm; nucleus; ubiquitin-protein ligase activity; zinc ion binding,PF00023;,,,,,,,,,XB35_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp44055_c0_seq1,363,46.281,0.5703747,2,16,,2.00E-29,Q96PE2,Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4),Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4),GO:0005089; GO:0030036; GO:0097190; GO:0005829; GO:0005085; GO:0048011; GO:0043065; GO:0035023; GO:0051056; GO:0007264,Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; apoptotic signaling pathway; cytosol; guanyl-nucleotide exchange factor activity; neurotrophin TRK receptor signaling pathway; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00621;,2.00E-32,CHOYP_LOC658611.1.1,,,,,,,ARHGH_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] comp44072_c0_seq1,367,40.5995,0.4158223,16,0,,2.00E-11,O15031,Plexin-B2 (MM1),Plexin-B2 (MM1),GO:0005096; GO:0007420; GO:0005887; GO:0005622; GO:0001843; GO:0007405; GO:0043547; GO:0050772; GO:0032319; GO:0008360; GO:2001222; GO:0001932; GO:0017154,GTPase activator activity; brain development; integral to plasma membrane; intracellular; neural tube closure; neuroblast proliferation; positive regulation of GTPase activity; positive regulation of axonogenesis; regulation of Rho GTPase activity; regulation of cell shape; regulation of neuron migration; regulation of protein phosphorylation; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB2_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp44074_c0_seq1,355,48.7324,0.96321111,11,2,,1.00E-14,P16066,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0008528; GO:0005525; GO:0007589; GO:0042417; GO:0004383; GO:0042562; GO:0005887; GO:0035556; GO:0016941; GO:0016525; GO:0030308; GO:0048662; GO:0017046; GO:0030828; GO:0035815; GO:0035810; GO:0004672; GO:0007168; GO:0008217; GO:0050880; GO:0043114; GO:0042312,ATP binding; G-protein coupled peptide receptor activity; GTP binding; body fluid secretion; dopamine metabolic process; guanylate cyclase activity; hormone binding; integral to plasma membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of angiogenesis; negative regulation of cell growth; negative regulation of smooth muscle cell proliferation; peptide hormone binding; positive regulation of cGMP biosynthetic process; positive regulation of renal sodium excretion; positive regulation of urine volume; protein kinase activity; receptor guanylyl cyclase signaling pathway; regulation of blood pressure; regulation of blood vessel size; regulation of vascular permeability; regulation of vasodilation,PF01094;PF00211;PF07714;,4.00E-41,CHOYP_LOC726069.1.1,,,,,,,ANPRA_HUMAN,Homo sapiens (Human),body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of cardiac conduction [GO:1903779]; regulation of vascular permeability [GO:0043114]; regulation of vasodilation [GO:0042312] comp44079_c0_seq1,222,55.8559,0.98725962,0,13,,4.00E-22,P49211,60S ribosomal protein L32-1,60S ribosomal protein L32-1,GO:0022625; GO:0005730; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; nucleolus; structural constituent of ribosome; translation,PF01655;,,,,,,,,,RL321_ARATH,Arabidopsis thaliana (Mouse-ear cress),translation [GO:0006412] comp44084_c0_seq1,312,39.1026,1.09618583,9,10,,8.00E-19,Q8NEA9,Putative germ cell-less protein-like 1-like,Putative germ cell-less protein-like 1-like,GO:0030154; GO:0007275; GO:0016363; GO:0016567; GO:0007283,cell differentiation; multicellular organismal development; nuclear matrix; protein ubiquitination; spermatogenesis,PF00651;,,,,,,,,,GMCLL_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] comp44130_c0_seq1,379,47.7573,0.44776431,14,2,,2.00E-07,Q924A2,Protein capicua homolog,Protein capicua homolog,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF16090;PF00505;,,,,,,,,,CIC_MOUSE,Mus musculus (Mouse),"lung alveolus development [GO:0048286]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp44152_c0_seq1,270,41.4815,0.52930414,9,5,,,,,,,,,,,3.00E-13,ruditapes_c21802,,,,,,, comp44155_c0_seq1,248,44.3548,0.84094579,9,0,,7.00E-28,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,2.00E-31,CHOYP_RNF213.3.4,5.00E-17,ruditapes_c17600,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp44192_c0_seq1,229,41.048,0.46371852,6,1,,1.00E-13,Q6ZWJ1,Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip),Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip),GO:0005509; GO:0005737; GO:0015758; GO:0008286; GO:0045111; GO:0005634; GO:0006605,calcium ion binding; cytoplasm; glucose transport; insulin receptor signaling pathway; intermediate filament cytoskeleton; nucleus; protein targeting,PF00595;PF00397;,,,,,,,,,STXB4_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178] comp44205_c0_seq1,259,47.4903,0.96758487,3,31,,,,,,,,,2.00E-11,CHOYP_BRAFLDRAFT_69134.2.13,,,,,,,,, comp44210_c0_seq1,230,46.5217,0.89410557,5,0,,2.00E-11,P35033,Trypsin-3 (EC 3.4.21.4) (Trypsin III) (Fragment),Trypsin-3 (EC 3.4.21.4) (Trypsin III) (Fragment),GO:0007586; GO:0005615; GO:0046872; GO:0006508; GO:0004252,digestion; extracellular space; metal ion binding; proteolysis; serine-type endopeptidase activity,PF00089;,,,,,,,,,TRY3_SALSA,Salmo salar (Atlantic salmon),digestion [GO:0007586] comp44216_c0_seq1,227,50.6608,0.23701084,0,8,,6.00E-28,Q28CZ9,Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R),Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R),GO:0004128; GO:0005783; GO:0020037; GO:0046872,"cytochrome-b5 reductase activity, acting on NAD(P)H; endoplasmic reticulum; heme binding; metal ion binding",PF04969;PF00173;PF00970;PF00175;,4.00E-20,CHOYP_NB5R4.1.1,,,,,,,NB5R4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),generation of precursor metabolites and energy [GO:0006091]; superoxide metabolic process [GO:0006801] comp44240_c0_seq1,236,41.1017,0.70717382,3,14,,4.00E-18,O88845,"A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)","A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)",GO:0005739; GO:0005886; GO:0051018; GO:0008104; GO:0038032,mitochondrion; plasma membrane; protein kinase A binding; protein localization; termination of G-protein coupled receptor signaling pathway,PF00615;,,,,,,,,,AKA10_MOUSE,Mus musculus (Mouse),protein localization [GO:0008104] comp44256_c0_seq1,389,38.3033,0.563384,10,31,,1.00E-07,Q9VGG5,Cadherin-87A,Cadherin-87A,GO:0005509; GO:0016339; GO:0007156; GO:0005887,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to plasma membrane,PF00028;,,,,,,,,,CAD87_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp44274_c0_seq1,226,40.2655,0.33813969,11,0,,4.00E-17,Q99MS3,Mpv17-like protein (M-LP),Mpv17-like protein (M-LP),GO:0016021; GO:0005739; GO:0005778; GO:0005777; GO:0072593,integral to membrane; mitochondrion; peroxisomal membrane; peroxisome; reactive oxygen species metabolic process,PF04117;,,,,,,,,,MP17L_MOUSE,Mus musculus (Mouse),negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; reactive oxygen species metabolic process [GO:0072593] comp44280_c0_seq1,207,39.1304,0.12698709,2,0,,6.00E-14,Q9Y5X2,Sorting nexin-8,Sorting nexin-8,GO:0007154; GO:0031901; GO:0034498; GO:0006886; GO:0035091,cell communication; early endosome membrane; early endosome to Golgi transport; intracellular protein transport; phosphatidylinositol binding,PF00787;,6.00E-36,CHOYP_LOC575600.1.1,,,,,,,SNX8_HUMAN,Homo sapiens (Human),early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] comp44290_c0_seq1,216,47.2222,1.50233989,0,12,,2.00E-08,Q9CXI3,DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X),GO:0006584; GO:0005507; GO:0004500; GO:0005789; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; endoplasmic reticulum membrane; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD1_MOUSE,Mus musculus (Mouse), comp44291_c0_seq1,320,39.6875,0.42326363,15,9,,7.00E-08,Q06AU5,Ras-related protein Rab-32,Ras-related protein Rab-32,GO:0005525; GO:0005739; GO:0045335; GO:0030670; GO:0090382; GO:0015031; GO:0007264,GTP binding; mitochondrion; phagocytic vesicle; phagocytic vesicle membrane; phagosome maturation; protein transport; small GTPase mediated signal transduction,PF00071;,2.00E-18,CHOYP_PHUM_PHUM310360.1.1,,,,,,,RAB32_PIG,Sus scrofa (Pig),melanosome organization [GO:0032438]; phagosome maturation [GO:0090382]; small GTPase mediated signal transduction [GO:0007264] comp44301_c0_seq2,250,40.4,1.28720008,4,8,,8.00E-07,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp44362_c0_seq1,329,42.8571,0.41130417,6,9,,8.00E-36,Q924N4,Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3),GO:0016323; GO:0071477; GO:0016021; GO:0006813; GO:0015379,basolateral plasma membrane; cellular hypotonic salinity response; integral to membrane; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,7.00E-63,CHOYP_S12A4.1.1,,,,,,,S12A6_MOUSE,Mus musculus (Mouse),cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826] comp44376_c0_seq1,226,41.5929,0.83572736,7,5,,1.00E-07,Q98931,Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B),Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B),GO:0005509; GO:0006897; GO:0016021; GO:0021517,calcium ion binding; endocytosis; integral to membrane; ventral spinal cord development,PF00057;PF00058;,,,,,,,,,LRP8_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897]; ventral spinal cord development [GO:0021517] comp44379_c0_seq1,243,47.3251,0.88567743,2,11,,3.00E-06,O02713,Solute carrier family 22 member 2 (Apical organic cation transporter) (Organic cation transporter 2),Solute carrier family 22 member 2 (Apical organic cation transporter) (Organic cation transporter 2),GO:0016021; GO:0015075,integral to membrane; ion transmembrane transporter activity,PF00083;,,,,,,,,,S22A2_PIG,Sus scrofa (Pig),choline transport [GO:0015871]; dopamine transport [GO:0015872] comp44492_c0_seq1,355,48.4507,0.38512814,7,6,,1.00E-40,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,,,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp44503_c0_seq1,230,49.5652,1.05001985,3,0,,4.00E-27,P02594,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,7.00E-23,CHOYP_CALM.47.50,1.00E-18,ruditapes_lrc36488,,,,,CALM_ELEEL,Electrophorus electricus (Electric eel) (Gymnotus electricus), comp44508_c0_seq1,227,40.5286,0.43616341,3,0,,3.00E-13,Q7ZU45,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,,,,,,,,,,TTC25_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp44509_c0_seq1,394,44.4162,0.42795509,10,8,,1.00E-20,A0JM23,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0060271; GO:0090090; GO:0072372; GO:2000095,"Wnt receptor signaling pathway; cilium morphogenesis; negative regulation of canonical Wnt receptor signaling pathway; primary cilium; regulation of Wnt receptor signaling pathway, planar cell polarity pathway",PF13176;,4.00E-23,CHOYP_NPHP3.1.1,,,,,,,NPHP3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cilium morphogenesis [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]" comp44531_c0_seq1,273,47.9853,0.57928896,4,11,,,,,,,,,6.00E-12,CHOYP_SDK2.1.1,,,,,,,,, comp44542_c0_seq1,211,44.5498,0.3840666,8,10,,8.00E-18,Q2HZX7,Protein fuzzy homolog (Xfy),Protein fuzzy homolog (Xfy),GO:0042384; GO:0005737; GO:0005856; GO:0010172; GO:0048704; GO:0001736; GO:0001843; GO:0015031; GO:0008589,cilium assembly; cytoplasm; cytoskeleton; embryonic body morphogenesis; embryonic skeletal system morphogenesis; establishment of planar polarity; neural tube closure; protein transport; regulation of smoothened signaling pathway,,2.00E-17,CHOYP_FUZZY.1.1,,,,,,,FUZZY_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium assembly [GO:0042384]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589] comp44543_c0_seq1,541,41.0351,0.6289288,5,17,,2.00E-58,Q99L88,Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin-2),Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin-2),GO:0030054; GO:0005737; GO:0005856; GO:0005543; GO:0043234; GO:0042383; GO:0045202,cell junction; cytoplasm; cytoskeleton; phospholipid binding; protein complex; sarcolemma; synapse,PF00595;PF00169;,6.00E-54,CHOYP_LOC592864.1.1,,,,,,,SNTB1_MOUSE,Mus musculus (Mouse), comp44578_c0_seq1,215,49.3023,0.54001168,3,10,,7.00E-30,Q92736,Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor),Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor),GO:0030509; GO:0086029; GO:0030018; GO:0034704; GO:0005509; GO:0048763; GO:0035584; GO:0005516; GO:0060070; GO:0060048; GO:0003300; GO:0086064; GO:0071313; GO:0071872; GO:0005513; GO:0003143; GO:0072599; GO:0044325; GO:0014701; GO:0003220; GO:0005886; GO:1901896; GO:0010460; GO:0086094; GO:0051284; GO:0034236; GO:0034237; GO:0010881; GO:0086005; GO:0014808; GO:0001666; GO:0051775; GO:0005219; GO:0043924; GO:0097050,BMP signaling pathway; Purkinje myocyte to ventricular cardiac muscle cell signaling; Z disc; calcium channel complex; calcium ion binding; calcium-induced calcium release activity; calcium-mediated signaling using intracellular calcium source; calmodulin binding; canonical Wnt receptor signaling pathway; cardiac muscle contraction; cardiac muscle hypertrophy; cell communication by electrical coupling involved in cardiac conduction; cellular response to caffeine; cellular response to epinephrine stimulus; detection of calcium ion; embryonic heart tube morphogenesis; establishment of protein localization to endoplasmic reticulum; ion channel binding; junctional sarcoplasmic reticulum membrane; left ventricular cardiac muscle tissue morphogenesis; plasma membrane; positive regulation of calcium-transporting ATPase activity; positive regulation of heart rate; positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction; positive regulation of sequestering of calcium ion; protein kinase A catalytic subunit binding; protein kinase A regulatory subunit binding; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of ventricular cardiac muscle cell action potential; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; response to hypoxia; response to redox state; ryanodine-sensitive calcium-release channel activity; suramin binding; type B pancreatic cell apoptotic process,PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,2.00E-48,CHOYP_LOC100643070.1.1,,,,,,,RYR2_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; calcium-mediated signaling [GO:0019722]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to epinephrine stimulus [GO:0071872]; detection of calcium ion [GO:0005513]; embryonic heart tube morphogenesis [GO:0003143]; establishment of protein localization to endoplasmic reticulum [GO:0072599]; ion transmembrane transport [GO:0034220]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; positive regulation of calcium-transporting ATPase activity [GO:1901896]; positive regulation of heart rate [GO:0010460]; positive regulation of sequestering of calcium ion [GO:0051284]; positive regulation of the force of heart contraction [GO:0098735]; Purkinje myocyte to ventricular cardiac muscle cell signaling [GO:0086029]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart rate [GO:0002027]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; release of sequestered calcium ion into cytosol [GO:0051209]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to caffeine [GO:0031000]; response to hypoxia [GO:0001666]; response to muscle activity [GO:0014850]; response to muscle stretch [GO:0035994]; response to redox state [GO:0051775]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; type B pancreatic cell apoptotic process [GO:0097050]; ventricular cardiac muscle cell action potential [GO:0086005] comp44593_c0_seq1,283,36.7491,0.42579242,6,6,,1.00E-10,Q99M85,Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt),Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,SCRT1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; transcription, DNA-templated [GO:0006351]" comp44597_c0_seq1,209,33.0144,1.11113655,3,10,,,,,,,,,,,6.00E-15,ruditapes2_c1055,,,,,,, comp44606_c0_seq1,698,41.2607,0.50684108,26,13,,1.00E-33,Q21653,Uncharacterized protein R02F2.2,Rho guanine nucleotide exchange factor osg-1 (Oxidative stress-susceptible GEF1),GO:0005089; GO:0035556; GO:0035023,Rho guanyl-nucleotide exchange factor activity; intracellular signal transduction; regulation of Rho protein signal transduction,PF00621;,2.00E-68,CHOYP_LOC658611.1.1,,,,,,,YNG2_CAEEL,Caenorhabditis elegans,intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979] comp44693_c1_seq1,290,43.7931,0.57824831,14,3,,9.00E-16,Q80WK7,Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3),Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3),GO:0016021; GO:0031902; GO:0005765; GO:0005337; GO:0015858,integral to membrane; late endosome membrane; lysosomal membrane; nucleoside transmembrane transporter activity; nucleoside transport,PF01733;,,,,,,,,,S29A3_RAT,Rattus norvegicus (Rat),nucleoside transport [GO:0015858] comp44715_c0_seq1,392,49.2347,0.43473734,9,27,,3.00E-19,Q5T011,Protein SZT2 (Seizure threshold 2 protein homolog),Protein SZT2 (Seizure threshold 2 protein homolog),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp44720_c0_seq1,328,57.9268,1.41862619,7,2,,4.00E-18,Q86AX3,Probable urocanate hydratase (Urocanase) (EC 4.2.1.49) (Imidazolonepropionate hydrolase),Probable urocanate hydratase (Urocanase) (EC 4.2.1.49) (Imidazolonepropionate hydrolase),GO:0019556; GO:0019557; GO:0016153,histidine catabolic process to glutamate and formamide; histidine catabolic process to glutamate and formate; urocanate hydratase activity,PF01175;,,,,,,,,,HUTU_DICDI,Dictyostelium discoideum (Slime mold),histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] comp44722_c0_seq1,452,40.9292,0.84772345,3,25,,7.00E-45,O61735,Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1),Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1),GO:0003677; GO:0048148; GO:0032922; GO:0005737; GO:0008062; GO:0045475; GO:0000122; GO:0005634; GO:0045944; GO:0046982; GO:0045187; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"DNA binding; behavioral response to cocaine; circadian regulation of gene expression; cytoplasm; eclosion rhythm; locomotor rhythm; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; regulation of circadian sleep/wake cycle, sleep; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;,6.00E-47,CHOYP_LOC100552330.1.1,,,,,,,CLOCK_DROME,Drosophila melanogaster (Fruit fly),"behavioral response to cocaine [GO:0048148]; circadian regulation of gene expression [GO:0032922]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; eclosion rhythm [GO:0008062]; entrainment of circadian clock [GO:0009649]; locomotor rhythm [GO:0045475]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to temperature stimulus [GO:0009266]; rhythmic behavior [GO:0007622]; transcription, DNA-templated [GO:0006351]" comp44725_c0_seq1,283,47.3498,0.92038186,0,12,,2.00E-12,A2AJ76,Hemicentin-2,Hemicentin-2,GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus,PF12662;PF07645;PF07474;PF07679;,,,,,,,,,HMCN2_MOUSE,Mus musculus (Mouse),response to stimulus [GO:0050896] comp44726_c0_seq1,230,48.2609,0.99835664,6,0,,9.00E-09,P41950,EGF-like domain-containing protein D1044.2,Dendrite extension defective protein 1,GO:0003391; GO:0005509; GO:0007160; GO:0032590; GO:0016021,amphid sensory organ dendrite retrograde extension; calcium ion binding; cell-matrix adhesion; dendrite membrane; integral to membrane,PF12947;PF06119;,,,,,,,,,YLK2_CAEEL,Caenorhabditis elegans,amphid sensory organ dendrite retrograde extension [GO:0003391]; cell-matrix adhesion [GO:0007160] comp44732_c0_seq1,259,48.6486,0.45867619,12,0,,,,,,,,,1.00E-13,CHOYP_LOC100367864.2.3,,,,,,,,, comp44801_c1_seq1,232,39.2241,0.67733817,5,0,,3.00E-10,O46564,Bone morphogenetic protein 2 (BMP-2),Bone morphogenetic protein 2 (BMP-2),GO:0070700; GO:0003130; GO:0007219; GO:0046332; GO:0060395; GO:0000187; GO:0003181; GO:0035630; GO:0001658; GO:0060317; GO:0055007; GO:0055008; GO:0035051; GO:0009986; GO:0071773; GO:0071407; GO:0002062; GO:0060128; GO:0035054; GO:0003203; GO:0005615; GO:0040007; GO:0001701; GO:0006954; GO:0048839; GO:0072138; GO:0003308; GO:0032348; GO:0051042; GO:0090090; GO:2000726; GO:0045786; GO:0008285; GO:2000065; GO:0043569; GO:0000122; GO:0042475; GO:0001649; GO:0060389; GO:0060039; GO:0019211; GO:0070374; GO:0060804; GO:0043065; GO:0048711; GO:0030501; GO:0061036; GO:0030335; GO:0001938; GO:0010718; GO:0045600; GO:0045666; GO:0042482; GO:0045669; GO:0033690; GO:1900745; GO:0010862; GO:0010922; GO:0045944; GO:1901522; GO:0031648; GO:0006029; GO:0042487; GO:0001666; GO:0004745; GO:0021537; GO:0021978; GO:0060129,BMP receptor binding; BMP signaling pathway involved in heart induction; Notch signaling pathway; SMAD binding; SMAD protein signal transduction; activation of MAPK activity; atrioventricular valve morphogenesis; bone mineralization involved in bone maturation; branching involved in ureteric bud morphogenesis; cardiac epithelial to mesenchymal transition; cardiac muscle cell differentiation; cardiac muscle tissue morphogenesis; cardiocyte differentiation; cell surface; cellular response to BMP stimulus; cellular response to organic cyclic compound; chondrocyte differentiation; corticotropin hormone secreting cell differentiation; embryonic heart tube anterior/posterior pattern specification; endocardial cushion morphogenesis; extracellular space; growth; in utero embryonic development; inflammatory response; inner ear development; mesenchymal cell proliferation involved in ureteric bud development; negative regulation of Wnt receptor signaling pathway involved in heart development; negative regulation of aldosterone biosynthetic process; negative regulation of calcium-independent cell-cell adhesion; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cardiac muscle cell differentiation; negative regulation of cell cycle; negative regulation of cell proliferation; negative regulation of cortisol biosynthetic process; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; odontogenesis of dentin-containing tooth; osteoblast differentiation; pathway-restricted SMAD protein phosphorylation; pericardium development; phosphatase activator activity; positive regulation of ERK1 and ERK2 cascade; positive regulation of Wnt receptor signaling pathway by BMP signaling pathway; positive regulation of apoptotic process; positive regulation of astrocyte differentiation; positive regulation of bone mineralization; positive regulation of cartilage development; positive regulation of cell migration; positive regulation of endothelial cell proliferation; positive regulation of epithelial to mesenchymal transition; positive regulation of fat cell differentiation; positive regulation of neuron differentiation; positive regulation of odontogenesis; positive regulation of osteoblast differentiation; positive regulation of osteoblast proliferation; positive regulation of p38MAPK cascade; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of phosphatase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; protein destabilization; proteoglycan metabolic process; regulation of odontogenesis of dentin-containing tooth; response to hypoxia; retinol dehydrogenase activity; telencephalon development; telencephalon regionalization; thyroid-stimulating hormone-secreting cell differentiation,PF00019;PF00688;,,,,,,,,,BMP2_RABIT,Oryctolagus cuniculus (Rabbit),"BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart induction [GO:0003130]; bone mineralization involved in bone maturation [GO:0035630]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiocyte differentiation [GO:0035051]; cartilage development [GO:0051216]; epithelial to mesenchymal transition [GO:0001837]; growth [GO:0040007]; mesenchymal cell differentiation [GO:0048762]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; osteoblast differentiation [GO:0001649]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatase activity [GO:0010922]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; SMAD protein signal transduction [GO:0060395]; telencephalon development [GO:0021537]" comp44826_c0_seq1,309,64.7249,1.30671782,1,6,,1.00E-19,P53382,Protein mrp homolog,Iron-sulfur cluster carrier protein,GO:0005524,ATP binding,PF01883;PF10609;,,,,,,,,,MRP_MYCLE,Mycobacterium leprae (strain TN), comp44830_c0_seq1,386,41.1917,0.8196536,15,5,,4.00E-30,O88576,Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3),Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3),GO:0006865; GO:0005887; GO:0005328; GO:0005886; GO:0005215,amino acid transport; integral to plasma membrane; neurotransmitter:sodium symporter activity; plasma membrane; transporter activity,PF00209;,3.00E-18,CHOYP_S620B.1.1,,,,,,,S6A18_MOUSE,Mus musculus (Mouse),amino acid transmembrane transport [GO:0003333]; transport [GO:0006810] comp44849_c0_seq1,238,44.1176,0.35619109,3,11,,3.00E-29,P22907,Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase),Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase),GO:0004418; GO:0018160; GO:0006782,hydroxymethylbilane synthase activity; peptidyl-pyrromethane cofactor linkage; protoporphyrinogen IX biosynthetic process,PF01379;PF03900;,,,4.00E-30,ruditapes_c7564,,,,,HEM3_MOUSE,Mus musculus (Mouse),astrocyte differentiation [GO:0048708]; cellular response to amine stimulus [GO:0071418]; cellular response to antibiotic [GO:0071236]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cytokine stimulus [GO:0071345]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to lead ion [GO:0071284]; organ regeneration [GO:0031100]; peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to amino acid [GO:0043200]; response to carbohydrate [GO:0009743]; response to cobalt ion [GO:0032025]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to methylmercury [GO:0051597]; response to vitamin [GO:0033273]; response to zinc ion [GO:0010043] comp44872_c0_seq1,381,40.1575,0.92048827,5,46,,9.00E-21,Q69DJ1,Sulfate transporter (Solute carrier family 26 member 2),Sulfate transporter (Solute carrier family 26 member 2),GO:0016021; GO:0008271; GO:0008272,integral to membrane; secondary active sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A2_BUBBU,Bubalus bubalis (Domestic water buffalo),ossification [GO:0001503] comp44878_c0_seq1,238,44.958,1.23295827,3,6,,5.00E-42,Q6NYB4,Protein mab-21-like 1,Protein mab-21-like 1,GO:0048568; GO:0005634,embryonic organ development; nucleus,PF03281;,5.00E-38,CHOYP_LOC661084.1.1,,,,,,,MB211_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),multicellular organism development [GO:0007275] comp44884_c0_seq1,235,47.234,0.57005863,4,27,,3.00E-25,O54924,Exocyst complex component 8 (Exocyst complex 84 kDa subunit),Exocyst complex component 8 (Exocyst complex 84 kDa subunit),GO:0034613; GO:0000145; GO:0006887; GO:0030426; GO:0005634; GO:0048471; GO:0005543; GO:0015031,cellular protein localization; exocyst; exocytosis; growth cone; nucleus; perinuclear region of cytoplasm; phospholipid binding; protein transport,PF16528;,4.00E-32,CHOYP_LOC100699161.1.1,,,,,,,EXOC8_RAT,Rattus norvegicus (Rat),cellular protein localization [GO:0034613]; endosome organization [GO:0007032]; exocyst assembly [GO:0001927]; exocyst localization [GO:0051601]; exocytosis [GO:0006887]; extracellular matrix disassembly [GO:0022617]; protein transport [GO:0015031] comp44906_c0_seq1,227,42.7313,0.40319085,0,14,,2.00E-10,O94868,FCH and double SH3 domains protein 2 (Carom) (SH3 multiple domains protein 3),F-BAR and double SH3 domains protein 2 (Carom) (SH3 multiple domains protein 3),,,PF00611;PF00018;PF14604;,,,,,,,,,FCSD2_HUMAN,Homo sapiens (Human), comp44929_c0_seq1,431,49.42,0.65164503,6,32,,4.00E-14,Q9VN14,Contactin,Contactin,GO:0031225; GO:0008366; GO:0030246; GO:0061343; GO:0060857; GO:0045197; GO:0021682; GO:0005886; GO:0005918; GO:0019991,anchored to membrane; axon ensheathment; carbohydrate binding; cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; establishment or maintenance of epithelial cell apical/basal polarity; nerve maturation; plasma membrane; septate junction; septate junction assembly,PF00041;PF00047;PF00059;,,,,,,,,,CONT_DROME,Drosophila melanogaster (Fruit fly),axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] comp44940_c0_seq1,222,43.2432,0.58995906,5,0,,3.00E-29,Q9WTN0,"Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)","Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)",GO:0005737; GO:0004161; GO:0045337; GO:0004311; GO:0033384; GO:0033386; GO:0004337; GO:0006720; GO:0046872,cytoplasm; dimethylallyltranstransferase activity; farnesyl diphosphate biosynthetic process; farnesyltranstransferase activity; geranyl diphosphate biosynthetic process; geranylgeranyl diphosphate biosynthetic process; geranyltranstransferase activity; isoprenoid metabolic process; metal ion binding,PF00348;,1.00E-25,CHOYP_GGPPS.1.1,,,,,,,GGPPS_MOUSE,Mus musculus (Mouse),farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid metabolic process [GO:0006720] comp44941_c0_seq1,242,46.281,0.23516531,11,0,,3.00E-21,Q5YLM1,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0071926; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0004806,arachidonic acid metabolic process; endocannabinoid signaling pathway; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; triglyceride lipase activity,PF01764;,7.00E-17,CHOYP_INAE.1.1,,,,,,,DGLA_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136] comp44946_c0_seq1,656,44.5122,0.34097744,24,1,,,,,,,,,7.00E-29,CHOYP_BRAFLDRAFT_80394.4.9,,,,,,,,, comp44966_c0_seq1,372,41.6667,0.71982976,19,0,,2.00E-16,A4Q9E4,Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 2),Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 2),GO:0006464; GO:0016874,cellular protein modification process; ligase activity,PF03133;,2.00E-25,CHOYP_BRAFLDRAFT_279373.1.1,,,,,,,TTLL2_MOUSE,Mus musculus (Mouse),cellular protein modification process [GO:0006464] comp44968_c0_seq1,221,48.4163,0.70852515,7,0,,3.00E-18,Q9EPQ0,Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) (Fragment),Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) (Fragment),GO:0008273; GO:0006874; GO:0016021; GO:0005886; GO:0015293,"calcium, potassium:sodium antiporter activity; cellular calcium ion homeostasis; integral to membrane; plasma membrane; symporter activity",PF01699;,,,,,,,,,NCKX3_RAT,Rattus norvegicus (Rat),calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874] comp44972_c0_seq1,409,42.7873,0.54333746,4,17,,9.00E-25,P27046,"Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0006491; GO:0030246; GO:0005801; GO:0016799; GO:0001701; GO:0016021; GO:0001889; GO:0048286; GO:0006013; GO:0015923; GO:0004572; GO:0007005; GO:0050769; GO:0007585; GO:0060042; GO:0007033; GO:0008270,"Golgi membrane; N-glycan processing; carbohydrate binding; cis-Golgi network; hydrolase activity, hydrolyzing N-glycosyl compounds; in utero embryonic development; integral to membrane; liver development; lung alveolus development; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; mitochondrion organization; positive regulation of neurogenesis; respiratory gaseous exchange; retina morphogenesis in camera-type eye; vacuole organization; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A1_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033] comp44996_c0_seq1,247,55.8704,1.00320997,1,4,,2.00E-06,P96919,Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) (Exodeoxyribonuclease V 67 kDa polypeptide),,GO:0005524; GO:0006281; GO:0005618; GO:0005829; GO:0004519; GO:0008854; GO:0009338; GO:0004386; GO:0090305; GO:0005886,ATP binding; DNA repair; cell wall; cytosol; endonuclease activity; exodeoxyribonuclease V activity; exodeoxyribonuclease V complex; helicase activity; nucleic acid phosphodiester bond hydrolysis; plasma membrane,,,,,,,,,,EX5A_MYCTU,, comp45018_c0_seq1,413,39.7094,1.17421199,15,1,,4.00E-12,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,,,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp45028_c0_seq1,207,39.6135,0.37934016,3,13,,2.00E-07,Q9P278,Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein),Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein),GO:0005737; GO:0008630; GO:0000122; GO:0005634; GO:0005886; GO:0033138; GO:0006468,cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of transcription from RNA polymerase II promoter; nucleus; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein phosphorylation,PF14638;PF14637;PF14636;,,,,,,,,,FNIP2_HUMAN,Homo sapiens (Human),intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] comp45102_c0_seq1,218,47.2477,0.8436233,3,8,,6.00E-11,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp45121_c0_seq1,300,44.3333,0.54455603,3,6,,9.00E-46,Q8BFW7,Lipoma-preferred partner homolog,Lipoma-preferred partner homolog,GO:0007155; GO:0005737; GO:0005925; GO:0005634; GO:0008270,cell adhesion; cytoplasm; focal adhesion; nucleus; zinc ion binding,PF00412;,,,,,,,,,LPP_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp45122_c0_seq1,216,47.2222,0.75552877,1,10,,9.00E-06,Q5FVR3,CD302 antigen (C-type lectin domain family 13 member A) (CD antigen CD302),CD302 antigen (C-type lectin domain family 13 member A) (CD antigen CD302),GO:0030246; GO:0005938; GO:0030175; GO:0016021; GO:0005902,carbohydrate binding; cell cortex; filopodium; integral to membrane; microvillus,PF00059;,,,,,,,,,CD302_RAT,Rattus norvegicus (Rat), comp45123_c0_seq1,372,41.9355,0.49338981,9,12,,2.00E-51,P40692,DNA mismatch repair protein Mlh1 (MutL protein homolog 1),DNA mismatch repair protein Mlh1 (MutL protein homolog 1),GO:0005524; GO:0016887; GO:0032389; GO:0032390; GO:0005712; GO:0006303; GO:0032137; GO:0008630; GO:0045190; GO:0001673; GO:0007060; GO:0043060; GO:0006298; GO:0045950; GO:0000289; GO:0048477; GO:0007131; GO:0000712; GO:0016446; GO:0007283; GO:0051257; GO:0007129; GO:0000795,ATP binding; ATPase activity; MutLalpha complex; MutLbeta complex; chiasma; double-strand break repair via nonhomologous end joining; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; male germ cell nucleus; male meiosis chromosome segregation; meiotic metaphase I plate congression; mismatch repair; negative regulation of mitotic recombination; nuclear-transcribed mRNA poly(A) tail shortening; oogenesis; reciprocal meiotic recombination; resolution of meiotic recombination intermediates; somatic hypermutation of immunoglobulin genes; spermatogenesis; spindle midzone assembly involved in meiosis; synapsis; synaptonemal complex,PF01119;PF16413;,2.00E-32,CHOYP_MLH1.1.1,,,,,,,MLH1_HUMAN,Homo sapiens (Human),double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp45151_c0_seq1,247,42.915,0.36364232,7,5,,2.00E-12,Q9D565,WD repeat-containing protein 64,WD repeat-containing protein 64,,,PF00400;,,,,,,,,,WDR64_MOUSE,Mus musculus (Mouse), comp45169_c0_seq1,571,43.0823,1.02089155,26,0,,,,,,,,,3.00E-13,CHOYP_ACDOPBH.7.9,,,,,,,,, comp45169_c0_seq2,232,46.1207,0.89554424,0,0,,6.00E-10,Q7Z0T3,Temptin,Temptin,GO:0005576,extracellular region,,,,1.00E-11,ruditapes2_c1699,,,,,TEMPT_APLCA,Aplysia californica (California sea hare), comp45178_c0_seq1,209,41.6268,0.57190852,1,3,,3.00E-10,Q9Z139,"Tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1)","Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1)",GO:0005524; GO:0005887; GO:0004714; GO:0007169,ATP binding; integral to plasma membrane; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF01392;PF07679;PF00051;PF07714;,,,,,,,,,ROR1_MOUSE,Mus musculus (Mouse),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055] comp45202_c0_seq1,319,43.5737,0.41830476,7,13,,9.00E-09,Q90Z04,Cell adhesion molecule-related/down-regulated by oncogenes,Cell adhesion molecule-related/down-regulated by oncogenes,GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;,,,,,,,,,CDON_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155]; embryonic morphogenesis [GO:0048598]; positive regulation of myoblast differentiation [GO:0045663]; regulation of neuron differentiation [GO:0045664]; smoothened signaling pathway [GO:0007224] comp45212_c0_seq1,270,41.4815,0.3484458,9,0,,7.00E-11,P20478,Glutamine synthetase 2 cytoplasmic (EC 6.3.1.2) (Glutamate--ammonia ligase 2),Glutamine synthetase 2 cytoplasmic (EC 6.3.1.2) (Glutamate--ammonia ligase 2),GO:0005524; GO:0005737; GO:0006538; GO:0004356; GO:0006542; GO:0045213; GO:0007416,ATP binding; cytoplasm; glutamate catabolic process; glutamate-ammonia ligase activity; glutamine biosynthetic process; neurotransmitter receptor metabolic process; synapse assembly,PF00120;PF03951;,,,,,,,,,GLNA2_DROME,Drosophila melanogaster (Fruit fly),glutamate catabolic process [GO:0006538]; glutamine biosynthetic process [GO:0006542]; neurotransmitter receptor metabolic process [GO:0045213]; synapse assembly [GO:0007416] comp45233_c0_seq1,368,65.7609,1.05854207,2,17,,1.00E-17,Q8XXY9,Nod factor export ATP-binding protein I (EC 3.6.3.-) (Nodulation ATP-binding protein I),Nod factor export ATP-binding protein I (EC 3.6.3.-) (Nodulation ATP-binding protein I),GO:0005524; GO:0006200; GO:0016887; GO:0009877; GO:0005886; GO:0005215,ATP binding; ATP catabolic process; ATPase activity; nodulation; plasma membrane; transporter activity,PF00005;,,,,,,,,,NODI_RALSO,Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum),nodulation [GO:0009877] comp45280_c0_seq1,306,38.8889,0.97885103,0,0,,6.00E-07,P10077,Zinc finger protein 27 (Zfp-27) (Protein mKR4),Zinc finger protein 27 (Zfp-27) (Protein mKR4),GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZFP27_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp45280_c0_seq2,365,39.4521,1.06644157,0,16,,6.00E-06,Q14591,Zinc finger protein 271 (CT-ZFP48) (Epstein-Barr virus-induced zinc finger protein) (EBV-induced zinc finger protein) (ZNF-EB) (Zinc finger protein HZF7) (Zinc finger protein ZNFphex133) (Zinc finger protein dp) (ZNF-dp),,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,ZN271_HUMAN,, comp45291_c0_seq1,272,43.3824,1.10082133,7,8,,3.00E-21,Q9U1M8,Myosin-I heavy chain (Class VII unconventional myosin) (DdMVII) (DdM7),Myosin-I heavy chain (Class VII unconventional myosin) (DdMVII) (DdM7),GO:0005524; GO:0003779; GO:0030048; GO:0030898; GO:0031252; GO:0000902; GO:0031589; GO:0005829; GO:0030175; GO:0046847; GO:0003774; GO:0016459; GO:0001891; GO:0006909; GO:0043621; GO:0009847,ATP binding; actin binding; actin filament-based movement; actin-dependent ATPase activity; cell leading edge; cell morphogenesis; cell-substrate adhesion; cytosol; filopodium; filopodium assembly; motor activity; myosin complex; phagocytic cup; phagocytosis; protein self-association; spore germination,PF00063;PF00784;PF07653;,,,,,,,,,MYOI_DICDI,Dictyostelium discoideum (Slime mold),actin filament-based movement [GO:0030048]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; filopodium assembly [GO:0046847]; phagocytosis [GO:0006909]; spore germination [GO:0009847] comp45316_c0_seq1,383,46.9974,0.43886013,9,8,,2.00E-14,Q9ULM0,Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1),Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1),GO:0005856; GO:0005543,cytoskeleton; phospholipid binding,PF00373;PF00784;PF00169;,,,,,,,,,PKHH1_HUMAN,Homo sapiens (Human), comp45331_c0_seq1,358,59.2179,1.02325551,0,22,,1.00E-22,P11652,Methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) (MCB-beta),Methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) (MCB-beta),GO:0031419; GO:0019652; GO:0046872; GO:0004494,cobalamin binding; lactate fermentation to propionate and acetate; metal ion binding; methylmalonyl-CoA mutase activity,PF01642;,,,,,,,,,MUTA_PROFR,Propionibacterium freudenreichii subsp. shermanii,lactate fermentation to propionate and acetate [GO:0019652] comp45337_c0_seq1,258,42.6357,0.2569483,5,5,,2.00E-27,Q9W422,Josephin-like protein (EC 3.4.19.12),Josephin-like protein (EC 3.4.19.12),GO:0008242; GO:0006508,omega peptidase activity; proteolysis,PF02099;,,,,,,,,,JOSL_DROME,Drosophila melanogaster (Fruit fly),protein deubiquitination [GO:0016579] comp45392_c0_seq1,403,39.9504,0.44022687,7,4,,4.00E-21,Q3UX43,Ankyrin repeat domain-containing protein 13C,Ankyrin repeat domain-containing protein 13C,GO:0005789; GO:0048471; GO:0006621; GO:2000209; GO:0010869,endoplasmic reticulum membrane; perinuclear region of cytoplasm; protein retention in ER lumen; regulation of anoikis; regulation of receptor biosynthetic process,PF12796;PF11904;,5.00E-34,CHOYP_LOC100120406.1.1,,,,,,,AN13C_MOUSE,Mus musculus (Mouse),protein retention in ER lumen [GO:0006621]; regulation of anoikis [GO:2000209]; regulation of receptor biosynthetic process [GO:0010869] comp45405_c0_seq2,366,43.1694,0.35373758,2,3,,4.00E-31,Q9HAV4,Exportin-5 (Exp5) (Ran-binding protein 21),Exportin-5 (Exp5) (Ran-binding protein 21),GO:0003723; GO:0005829; GO:0010467; GO:0031047; GO:0005654; GO:0006611; GO:0008565; GO:0000049,RNA binding; cytosol; gene expression; gene silencing by RNA; nucleoplasm; protein export from nucleus; protein transporter activity; tRNA binding,PF08389;,,,,,,,,,XPO5_HUMAN,Homo sapiens (Human),gene silencing by RNA [GO:0031047]; positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825] comp45434_c0_seq1,299,44.1472,0.71651148,6,4,,4.00E-16,Q5RDY3,Kelch repeat and BTB domain-containing protein 2,Kelch repeat and BTB domain-containing protein 2,,,PF07707;PF00651;PF01344;,,,,,,,,,KBTB2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp45485_c0_seq1,266,43.985,0.39035639,1,9,,1.00E-15,Q2KHX6,Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein),Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein),GO:0050661; GO:0005739; GO:0000122; GO:0005634; GO:0005886; GO:0007605; GO:0047127; GO:0070324; GO:0042403; GO:0070327; GO:0003714,NADP binding; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; nucleus; plasma membrane; sensory perception of sound; thiomorpholine-carboxylate dehydrogenase activity; thyroid hormone binding; thyroid hormone metabolic process; thyroid hormone transport; transcription corepressor activity,PF02423;,2.00E-11,CHOYP_CRYM.1.1,,,,,,,CRYM_BOVIN,Bos taurus (Bovine),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; sensory perception of sound [GO:0007605]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp45490_c0_seq2,353,42.7762,1.00106848,0,9,,3.00E-06,Q6UXD5,Seizure 6-like protein 2,Seizure 6-like protein 2,GO:0005789; GO:0016021; GO:0005886,endoplasmic reticulum membrane; integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,SE6L2_HUMAN,Homo sapiens (Human), comp45535_c0_seq1,435,59.0805,1.13748933,0,19,,1.00E-35,P25310,"Lysozyme M1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase M1)","Lysozyme M1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase M1)",GO:0005975; GO:0016998; GO:0005615; GO:0003796; GO:0009253,carbohydrate metabolic process; cell wall macromolecule catabolic process; extracellular space; lysozyme activity; peptidoglycan catabolic process,PF01183;,,,,,,,,,LYSM1_STRGL,Streptomyces globisporus,carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253] comp45567_c0_seq1,257,46.6926,0.22933681,6,15,,2.00E-28,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,4.00E-20,CHOYP_FRAS1.4.4,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp45576_c0_seq1,366,37.9781,0.45590402,6,14,,4.00E-39,D3ZDK2,Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1),Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1),GO:0005524; GO:0005737; GO:0031398; GO:0070936; GO:0006511; GO:0004842,ATP binding; cytoplasm; positive regulation of protein ubiquitination; protein K48-linked ubiquitination; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00179;,1.00E-22,CHOYP_UBC2.2.3,1.00E-20,ruditapes2_c904,,,,,UB2D1_RAT,Rattus norvegicus (Rat),positive regulation of protein ubiquitination [GO:0031398]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] comp45596_c0_seq1,234,39.3162,0.44614009,9,2,,1.00E-08,Q5W8I8,Vesicular glutamate transporter 2.1 (Protein blumenkohl) (Solute carrier family 17 member 6-B) (Vesicular glutamate transporter 2-A),Vesicular glutamate transporter 2.1 (Protein blumenkohl) (Solute carrier family 17 member 6-B) (Vesicular glutamate transporter 2-A),GO:0030054; GO:0016021; GO:0043005; GO:0006836; GO:0050896; GO:0006814; GO:0015293; GO:0007268; GO:0030672; GO:0007601,cell junction; integral to membrane; neuron projection; neurotransmitter transport; response to stimulus; sodium ion transport; symporter activity; synaptic transmission; synaptic vesicle membrane; visual perception,PF07690;,1.00E-13,CHOYP_LOC659204.1.1,,,,,,,VGL2A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),chemical synaptic transmission [GO:0007268]; L-glutamate transmembrane transport [GO:0089711]; neurotransmitter transport [GO:0006836]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814]; visual perception [GO:0007601] comp455_c0_seq1,229,42.7948,1.24585709,2,0,,,,,,,,,2.00E-30,CHOYP_SIK3.1.1,,,,,,,,, comp455_c1_seq1,202,43.5644,0.52673839,2,0,,1.00E-32,Q9Y2K2,Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK),Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK),GO:0005524; GO:0005737; GO:0000287; GO:0004674,ATP binding; cytoplasm; magnesium ion binding; protein serine/threonine kinase activity,PF00069;,,,,,,,,,SIK3_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468] comp45667_c0_seq2,220,24.0909,1.29621446,0,4,,,,,,,,,,,4.00E-11,ruditapes2_c3033,,,,,,, comp45673_c0_seq1,300,38.6667,0.54088651,3,15,,4.00E-10,Q5DRE1,Protocadherin alpha-C2 (PCDH-alpha-C2),Protocadherin alpha-C2 (PCDH-alpha-C2),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDC2_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] comp45708_c0_seq1,227,46.696,0.16612344,3,1,,4.00E-14,P80108,Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),GO:0006507; GO:0002042; GO:0071277; GO:0071397; GO:0035690; GO:0071467; GO:0071401; GO:0002062; GO:0002430; GO:0005615; GO:0004621; GO:0097241; GO:0008286; GO:0005765; GO:0008285; GO:0010897; GO:0001503; GO:0046470; GO:0010694; GO:0043065; GO:0045919; GO:0010595; GO:0010907; GO:0010983; GO:0035774; GO:0051044; GO:0010867; GO:0005578; GO:1900076; GO:0009749; GO:0017080; GO:0070633,GPI anchor release; cell migration involved in sprouting angiogenesis; cellular response to calcium ion; cellular response to cholesterol; cellular response to drug; cellular response to pH; cellular response to triglyceride; chondrocyte differentiation; complement receptor mediated signaling pathway; extracellular space; glycosylphosphatidylinositol phospholipase D activity; hematopoietic stem cell migration to bone marrow; insulin receptor signaling pathway; lysosomal membrane; negative regulation of cell proliferation; negative regulation of triglyceride catabolic process; ossification; phosphatidylcholine metabolic process; positive regulation of alkaline phosphatase activity; positive regulation of apoptotic process; positive regulation of cytolysis; positive regulation of endothelial cell migration; positive regulation of glucose metabolic process; positive regulation of high-density lipoprotein particle clearance; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of membrane protein ectodomain proteolysis; positive regulation of triglyceride biosynthetic process; proteinaceous extracellular matrix; regulation of cellular response to insulin stimulus; response to glucose stimulus; sodium channel regulator activity; transepithelial transport,PF01839;PF00882;,,,,,,,,,PHLD_HUMAN,Homo sapiens (Human),cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633] comp45730_c0_seq1,201,51.7413,1.04627081,1,11,,2.00E-18,Q804S5,E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Protein mind bomb),E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Protein mind bomb),GO:0007219; GO:0005737; GO:0007275; GO:0005886; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; multicellular organismal development; plasma membrane; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),anterior lateral line development [GO:0048899]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; central nervous system development [GO:0007417]; determination of left/right symmetry [GO:0007368]; diencephalon development [GO:0021536]; digestive tract morphogenesis [GO:0048546]; embryonic camera-type eye development [GO:0031076]; embryonic pattern specification [GO:0009880]; endothelial cell development [GO:0001885]; epithelial cell development [GO:0002064]; floor plate formation [GO:0021508]; formation of anatomical boundary [GO:0048859]; generation of neurons [GO:0048699]; glial cell differentiation [GO:0010001]; habenula development [GO:0021986]; hair cell differentiation [GO:0035315]; heart development [GO:0007507]; hematopoietic stem cell differentiation [GO:0060218]; hemopoiesis [GO:0030097]; hindbrain development [GO:0030902]; inner ear receptor cell differentiation [GO:0060113]; lateral line nerve development [GO:0048892]; melanocyte differentiation [GO:0030318]; neural retina development [GO:0003407]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuron fate specification [GO:0048665]; Notch signaling pathway [GO:0007219]; notochord cell development [GO:0060035]; notochord development [GO:0030903]; optic cup formation involved in camera-type eye development [GO:0003408]; otic vesicle development [GO:0071599]; positive regulation of cell proliferation [GO:0008284]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein ubiquitination [GO:0031398]; posterior lateral line development [GO:0048916]; pronephric duct development [GO:0039022]; pronephros development [GO:0048793]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of glial cell differentiation [GO:0045685]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of receptor internalization [GO:0002090]; regulation of receptor-mediated endocytosis [GO:0048259]; rhombomere boundary formation [GO:0021654]; rhombomere development [GO:0021546]; somitogenesis [GO:0001756]; spinal cord association neuron specification [GO:0021519]; spinal cord development [GO:0021510]; spinal cord motor neuron cell fate specification [GO:0021520]; taste bud formation [GO:0061195]; trigeminal ganglion development [GO:0061551]; ubiquitin-dependent endocytosis [GO:0070086]; vasculogenesis [GO:0001570]; ventral spinal cord interneuron differentiation [GO:0021514]; ventral spinal cord interneuron specification [GO:0021521] comp45732_c0_seq1,285,64.2105,1.00146125,0,2,,3.00E-58,A1W9V0,Flagellar transcriptional regulator FlhD,Flagellar transcriptional regulator FlhD,GO:0003677; GO:0044780; GO:0005737; GO:0045893; GO:1902208; GO:0006351,"DNA binding; bacterial-type flagellum assembly; cytoplasm; positive regulation of transcription, DNA-dependent; regulation of bacterial-type flagellum assembly; transcription, DNA-dependent",PF05247;,,,,,,,,,FLHD_ACISJ,Acidovorax sp. (strain JS42),"bacterial-type flagellum assembly [GO:0044780]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of bacterial-type flagellum assembly [GO:1902208]; transcription, DNA-templated [GO:0006351]" comp45781_c0_seq1,637,42.5432,0.52209621,29,34,,1.00E-12,P86854,Perlucin-like protein,Perlucin-like protein,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,PLCL_MYTGA,Mytilus galloprovincialis (Mediterranean mussel), comp45791_c0_seq1,201,36.8159,0.44396703,3,4,,2.00E-12,Q149G0,UPF0561 protein C2orf68 homolog,UPF0561 protein C2orf68 homolog,,,PF10573;,,,,,,,,,CB068_MOUSE,Mus musculus (Mouse), comp45812_c0_seq1,302,41.7219,1.3060488,5,11,,2.00E-08,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp45825_c0_seq1,355,41.6901,0.13484955,8,0,,1.00E-18,Q8BNA6,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_MOUSE,Mus musculus (Mouse),cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842] comp45852_c0_seq1,220,40.9091,1.0332681,0,13,,,,,,,,,,,1.00E-11,ruditapes_c1892,,,,,,, comp45887_c0_seq1,201,45.2736,0.88340379,0,13,,3.00E-07,Q64285,Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase),Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase),GO:0047372; GO:0004091; GO:0046514; GO:0006707; GO:0005829; GO:0005615; GO:0030157; GO:0004771; GO:0004806,acylglycerol lipase activity; carboxylesterase activity; ceramide catabolic process; cholesterol catabolic process; cytosol; extracellular space; pancreatic juice secretion; sterol esterase activity; triglyceride lipase activity,PF00135;,,,,,,,,,CEL_MOUSE,Mus musculus (Mouse),ceramide catabolic process [GO:0046514]; cholesterol catabolic process [GO:0006707]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; pancreatic juice secretion [GO:0030157]; retinol metabolic process [GO:0042572]; synapse assembly [GO:0007416] comp45897_c0_seq1,337,43.0267,0.71144905,4,10,,3.00E-38,O08653,Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog),Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005634; GO:0030529,"ATP binding; RNA binding; chromosome, telomeric region; nucleus; ribonucleoprotein complex",PF13271;PF05386;PF05731;PF00400;,2.00E-44,CHOYP_BRAFLDRAFT_128562.1.4,,,,,,,TEP1_RAT,Rattus norvegicus (Rat),RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722] comp45907_c0_seq1,505,42.7723,0.54530973,10,12,,6.00E-29,Q91WC9,Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-),Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-),GO:0019369; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0004806,arachidonic acid metabolic process; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; triglyceride lipase activity,PF01764;,,,,,,,,,DGLB_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136] comp45945_c0_seq1,231,43.29,0.18590092,2,4,,1.00E-13,P52734,"FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)","FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)",GO:0005794; GO:0005089; GO:0030036; GO:0005856; GO:0007010; GO:0046847; GO:0030027; GO:0046872; GO:0005634; GO:0005543; GO:0005886; GO:0043088; GO:0008360; GO:0001726,Golgi apparatus; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; cytoskeleton; cytoskeleton organization; filopodium assembly; lamellipodium; metal ion binding; nucleus; phospholipid binding; plasma membrane; regulation of Cdc42 GTPase activity; regulation of cell shape; ruffle,PF01363;PF00169;PF00621;,,,,,,,,,FGD1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023] comp45964_c0_seq1,371,38.2749,0.60488244,15,0,,2.00E-21,Q61542,StAR-related lipid transfer protein 3 (Protein ES 64) (Protein MLN 64) (START domain-containing protein 3) (StARD3),StAR-related lipid transfer protein 3 (Protein ES 64) (Protein MLN 64) (START domain-containing protein 3) (StARD3),GO:0015485; GO:0030301; GO:0017127; GO:0016021; GO:0005770; GO:0031902; GO:0005739; GO:0006701,cholesterol binding; cholesterol transport; cholesterol transporter activity; integral to membrane; late endosome; late endosome membrane; mitochondrion; progesterone biosynthetic process,PF10457;PF01852;,,,,,,,,,STAR3_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869]; progesterone biosynthetic process [GO:0006701] comp45993_c0_seq1,203,44.335,0.90713664,0,8,,3.00E-15,Q9QZP2,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0071363; GO:0031670; GO:0005829; GO:0046872; GO:0008168; GO:0030308; GO:0005654; GO:0006355; GO:0006351,"DNA binding; cellular response to growth factor stimulus; cellular response to nutrient; cytosol; metal ion binding; methyltransferase activity; negative regulation of cell growth; nucleoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_RAT,Rattus norvegicus (Rat),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp46051_c0_seq1,235,44.2553,0.43785579,2,5,,5.00E-08,Q70JS2,Ring canal kelch homolog (Kelch-like protein 1) [Cleaved into: Kelch short protein],Ring canal kelch homolog (Kelch-like protein 1) [Cleaved into: Kelch short protein],GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF07707;PF00651;PF01344;,,,,,,,,,KELC_ANOST,Anopheles stephensi (Indo-Pakistan malaria mosquito), comp46082_c0_seq1,221,46.1538,0.59770455,2,4,,1.00E-07,Q622K8,Unconventional myosin heavy chain 6,Unconventional myosin heavy chain 6,GO:0005524; GO:0005737; GO:0003774; GO:0016459; GO:0008134,ATP binding; cytoplasm; motor activity; myosin complex; transcription factor binding,PF00373;PF00612;PF00063;PF00784;,6.00E-11,CHOYP_MYO22.2.2,,,,,,,HUM6_CAEBR,Caenorhabditis briggsae, comp46121_c0_seq1,539,41.9295,0.50783874,0,75,,7.00E-26,P18428,Lipopolysaccharide-binding protein (LBP),Lipopolysaccharide-binding protein (LBP),GO:0006953; GO:0009986; GO:0006968; GO:0071223; GO:0050829; GO:0050830; GO:0032490; GO:0005615; GO:0045087; GO:0002232; GO:0001530; GO:0015920; GO:0031663; GO:0070891; GO:0002281; GO:0044130; GO:0032720; GO:0008228; GO:0032722; GO:0032755; GO:0032757; GO:0043032; GO:0090023; GO:0060265; GO:0034145; GO:0042535; GO:0032760; GO:0005102; GO:0034142,acute-phase response; cell surface; cellular defense response; cellular response to lipoteichoic acid; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; detection of molecule of bacterial origin; extracellular space; innate immune response; leukocyte chemotaxis involved in inflammatory response; lipopolysaccharide binding; lipopolysaccharide transport; lipopolysaccharide-mediated signaling pathway; lipoteichoic acid binding; macrophage activation involved in immune response; negative regulation of growth of symbiont in host; negative regulation of tumor necrosis factor production; opsonization; positive regulation of chemokine production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of macrophage activation; positive regulation of neutrophil chemotaxis; positive regulation of respiratory burst involved in inflammatory response; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of tumor necrosis factor production; receptor binding; toll-like receptor 4 signaling pathway,PF01273;PF02886;,,,,,,,,,LBP_HUMAN,Homo sapiens (Human),"acute-phase response [GO:0006953]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lipopolysaccharide transport [GO:0015920]; liver development [GO:0001889]; macrophage activation involved in immune response [GO:0002281]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of tumor necrosis factor production [GO:0032720]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of membrane permeability [GO:0090559]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142]" comp46150_c0_seq1,578,43.4256,0.55694665,14,12,,1.00E-95,Q07722,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) (Fragment)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) (Fragment)",GO:0005509; GO:0035556; GO:0016042; GO:0004435; GO:0004871,calcium ion binding; intracellular signal transduction; lipid catabolic process; phosphatidylinositol phospholipase C activity; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,2.00E-54,CHOYP_PLCB4.1.2,,,,,,,PLCB4_BOVIN,Bos taurus (Bovine),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042] comp4615_c0_seq1,313,39.6166,0.49063001,7,0,,6.00E-09,A6QPT6,Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274),Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274),GO:0005813; GO:0005737; GO:0046872; GO:0005166; GO:0005730; GO:0005634; GO:0043565; GO:0000981,centrosome; cytoplasm; metal ion binding; neurotrophin p75 receptor binding; nucleolus; nucleus; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF01352;PF02023;PF00096;,,,,,,,,,ZN274_BOVIN,Bos taurus (Bovine),"regulation of histone H3-K9 trimethylation [GO:1900112]; transcription, DNA-templated [GO:0006351]" comp46175_c0_seq1,303,36.3036,0.60800662,6,9,,2.00E-28,Q9NPI0,Transmembrane protein 138,Transmembrane protein 138,GO:0005929; GO:0042384; GO:0016021; GO:0005774,cilium; cilium assembly; integral to membrane; vacuolar membrane,PF14935;,3.00E-23,CHOYP_BRAFLDRAFT_277366.1.1,,,,,,,TM138_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384] comp46193_c0_seq1,681,39.7944,0.63168928,13,82,,2.00E-21,Q3ZC91,Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-),Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-),GO:0005615; GO:0016798; GO:0006685; GO:0004767,"extracellular space; hydrolase activity, acting on glycosyl bonds; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity",PF00149;,,,,,,,,,ASM3A_BOVIN,Bos taurus (Bovine),nucleoside triphosphate catabolic process [GO:0009143] comp46194_c0_seq1,883,40.2039,0.59264538,36,1,,3.00E-11,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp46339_c0_seq1,295,44.7458,0.56556657,0,2,,4.00E-19,Q8IUA7,ATP-binding cassette sub-family A member 9,ATP-binding cassette sub-family A member 9,GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0005739; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; mitochondrion; transport,PF00005;,2.00E-11,CHOYP_TRIADDRAFT_53677.1.1,,,,,,,ABCA9_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869] comp46351_c0_seq1,294,45.2381,0.50613331,7,14,,7.00E-07,O89040,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)",GO:0031680; GO:0031683; GO:0005794; GO:0005509; GO:0005829; GO:0001580; GO:0035556; GO:0004435; GO:0005543; GO:0009395; GO:0005886; GO:0004871,G-protein beta/gamma-subunit complex; G-protein beta/gamma-subunit complex binding; Golgi apparatus; calcium ion binding; cytosol; detection of chemical stimulus involved in sensory perception of bitter taste; intracellular signal transduction; phosphatidylinositol phospholipase C activity; phospholipid binding; phospholipid catabolic process; plasma membrane; signal transducer activity,PF00168;PF09279;PF00388;PF00387;PF08703;,3.00E-36,CHOYP_PLCB4.2.2,,,,,,,PLCB2_RAT,Rattus norvegicus (Rat),detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395] comp46351_c1_seq1,397,40.0504,0.44719385,4,11,,8.00E-55,Q9QW07,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)",GO:0005509; GO:0005737; GO:0035556; GO:0016042; GO:0043267; GO:0004435; GO:0007602; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid catabolic process; negative regulation of potassium ion transport; phosphatidylinositol phospholipase C activity; phototransduction; signal transducer activity,PF00168;PF06631;PF09279;PF00388;PF00387;,4.00E-54,CHOYP_PLCB4.1.2,,,,,,,PLCB4_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602] comp46394_c0_seq1,268,36.5672,0.5622988,9,4,,1.00E-11,Q61116,Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93),Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN235_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp46402_c0_seq1,273,58.9744,0.88962233,0,14,,3.00E-14,B9MEZ2,"2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.11)","2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.11)",GO:0046538; GO:0006096,"2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; glycolysis",PF00300;,,,,,,,,,GPMA_ACIET,Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)),gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096] comp46416_c0_seq1,297,42.7609,0.22205915,6,7,,6.00E-43,Q8BLR9,Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase),Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase),GO:0005112; GO:0071532; GO:0031406; GO:0048037; GO:0005506; GO:0045746; GO:0061428; GO:0005634; GO:0036140; GO:0042265; GO:0042264; GO:0036139; GO:0036138; GO:0048471; GO:0045663; GO:0006351; GO:0008270,"Notch binding; ankyrin repeat binding; carboxylic acid binding; cofactor binding; iron ion binding; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; nucleus; peptidyl-asparagine 3-dioxygenase activity; peptidyl-asparagine hydroxylation; peptidyl-aspartic acid hydroxylation; peptidyl-histidine dioxygenase activity; peptidyl-histidine hydroxylation; perinuclear region of cytoplasm; positive regulation of myoblast differentiation; transcription, DNA-dependent; zinc ion binding",,2.00E-30,CHOYP_HIF1N.1.1,,,,,,,HIF1N_MOUSE,Mus musculus (Mouse),"negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; transcription, DNA-templated [GO:0006351]" comp46438_c0_seq1,257,60.7004,1.27556315,2,5,,3.00E-41,Q6A8H3,S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (MAT) (Methionine adenosyltransferase),S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (MAT) (Methionine adenosyltransferase),GO:0005524; GO:0006556; GO:0005737; GO:0000287; GO:0004478; GO:0006730,ATP binding; S-adenosylmethionine biosynthetic process; cytoplasm; magnesium ion binding; methionine adenosyltransferase activity; one-carbon metabolic process,PF02773;PF02772;PF00438;,,,,,,,,,METK_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] comp46460_c0_seq1,224,59.8214,1.3058296,2,4,,2.00E-06,P16528,Acetate operon repressor,Acetate operon repressor,GO:0003677; GO:0006097; GO:0006355; GO:0006351,"DNA binding; glyoxylate cycle; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09339;PF01614;,,,,,,,,,ICLR_ECOLI,Escherichia coli (strain K12),"glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp46474_c0_seq1,228,61.4035,0.95859963,0,22,,6.00E-51,P11482,Tubulin beta chain (Beta-tubulin),Tubulin beta chain (Beta-tubulin),GO:0005525; GO:0003924; GO:0005737; GO:0005874; GO:0007017; GO:0051258; GO:0005200,GTP binding; GTPase activity; cytoplasm; microtubule; microtubule-based process; protein polymerization; structural constituent of cytoskeleton,PF00091;PF03953;,2.00E-43,CHOYP_TBB4B.5.7,7.00E-46,ruditapes_lrc33589,,,,,TBB1_VOLCA,Volvox carteri (Green alga),microtubule-based process [GO:0007017] comp46478_c0_seq1,475,32.4211,0.72304118,8,15,,8.00E-30,Q2PYN8,Transcription factor LBX1 (Ladybird homeobox protein homolog 1),Transcription factor LBX1 (Ladybird homeobox protein homolog 1),GO:0030154; GO:0007517; GO:0051450; GO:0000122; GO:0005634; GO:0003700; GO:0005667; GO:0000976; GO:0006351,"cell differentiation; muscle organ development; myoblast proliferation; negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00046;,5.00E-16,CHOYP_LBX1.1.1,,,,,,,LBX1_XENLA,Xenopus laevis (African clawed frog),"cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp46493_c0_seq1,279,39.0681,1.04125746,3,11,,5.00E-09,O15156,Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK),Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK),GO:0003677; GO:0030154; GO:0007398; GO:0046872; GO:0007275; GO:0005634; GO:0045944; GO:0043370; GO:0043376; GO:0003700; GO:0006366,"DNA binding; cell differentiation; ectoderm development; metal ion binding; multicellular organismal development; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of CD4-positive, alpha-beta T cell differentiation; regulation of CD8-positive, alpha-beta T cell differentiation; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter",PF00651;,,,,,,,,,ZBT7B_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; multicellular organism development [GO:0007275]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp46512_c0_seq1,233,45.9227,0.73896098,3,14,,1.00E-12,Q15051,IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ),IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ),GO:0005516; GO:0005813; GO:0042384; GO:0005737; GO:0048496; GO:0045494; GO:0032391; GO:0001750,calmodulin binding; centrosome; cilium assembly; cytoplasm; maintenance of organ identity; photoreceptor cell maintenance; photoreceptor connecting cilium; photoreceptor outer segment,PF00612;,,,,,,,,,IQCB1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; maintenance of organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494] comp46549_c0_seq1,240,36.6667,0.12771817,6,8,,8.00E-08,Q9VS24,Protein melted,Protein melted,GO:0045464; GO:0007398; GO:0008286; GO:0006629; GO:0008152; GO:0007422; GO:0010314; GO:0005886; GO:2001020; GO:0030730,R8 cell fate specification; ectoderm development; insulin receptor signaling pathway; lipid metabolic process; metabolic process; peripheral nervous system development; phosphatidylinositol-5-phosphate binding; plasma membrane; regulation of response to DNA damage stimulus; sequestering of triglyceride,,,,,,,,,,MELT_DROME,Drosophila melanogaster (Fruit fly),cell fate specification [GO:0001708]; ectoderm development [GO:0007398]; insulin receptor signaling pathway [GO:0008286]; lipid metabolic process [GO:0006629]; metabolic process [GO:0008152]; peripheral nervous system development [GO:0007422]; R8 cell fate specification [GO:0045464]; regulation of response to DNA damage stimulus [GO:2001020]; sequestering of triglyceride [GO:0030730] comp46552_c0_seq1,278,47.1223,0.45546298,9,17,,2.00E-33,Q1LZH9,N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S),N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S),GO:0008449; GO:0030203; GO:0005764; GO:0046872,N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan metabolic process; lysosome; metal ion binding,PF00884;,,,,,,,,,GNS_BOVIN,Bos taurus (Bovine),glycosaminoglycan metabolic process [GO:0030203] comp46563_c0_seq1,212,57.5472,0.97550662,1,6,,3.00E-31,Q6A7E7,Trigger factor (TF) (EC 5.2.1.8) (PPIase),Trigger factor (TF) (EC 5.2.1.8) (PPIase),GO:0007049; GO:0051301; GO:0005737; GO:0003755; GO:0006457; GO:0000413; GO:0015031,cell cycle; cell division; cytoplasm; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization; protein transport,PF00254;PF05698;PF05697;,,,,,,,,,TIG_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cell cycle [GO:0007049]; cell division [GO:0051301]; protein folding [GO:0006457]; protein transport [GO:0015031] comp46570_c0_seq1,391,31.7136,0.61330258,22,8,,5.00E-15,Q9NV72,Zinc finger protein 701,Zinc finger protein 701,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN701_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp46582_c0_seq1,555,44.5045,0.40514175,19,15,,2.00E-43,Q810B6,Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif),Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif),GO:0006897; GO:0010008; GO:0046872,endocytosis; endosome membrane; metal ion binding,PF00023;PF12796;PF00651;PF01363;,7.00E-34,CHOYP_LOC100372945.2.2,,,,,,,ANFY1_MOUSE,Mus musculus (Mouse),"endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" comp46612_c0_seq1,613,41.7618,0.48721365,20,13,,1.00E-08,Q86VZ4,Low-density lipoprotein receptor-related protein 11 (LRP-11),Low-density lipoprotein receptor-related protein 11 (LRP-11),GO:0016021,integral to membrane,PF00057;PF07502;,,,,,,,,,LRP11_HUMAN,Homo sapiens (Human),multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414] comp46648_c0_seq1,279,45.5197,0.85671677,0,44,,4.00E-09,O88923,Latrophilin-2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2),Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2),GO:0004930; GO:0007420; GO:0030246; GO:0016021; GO:0043005; GO:0007218; GO:0005886,G-protein coupled receptor activity; brain development; carbohydrate binding; integral to membrane; neuron projection; neuropeptide signaling pathway; plasma membrane,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,,,,,,,,,LPHN2_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166] comp46663_c1_seq1,292,41.0959,0.48888226,4,14,,2.00E-06,Q5H8C1,FRAS1-related extracellular matrix protein 1 (Protein QBRICK),FRAS1-related extracellular matrix protein 1 (Protein QBRICK),GO:0005604; GO:0030246; GO:0007154; GO:0007160; GO:0097094; GO:0016021; GO:0046872,basement membrane; carbohydrate binding; cell communication; cell-matrix adhesion; craniofacial suture morphogenesis; integral to membrane; metal ion binding,PF03160;PF00059;,,,,,,,,,FREM1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] comp46665_c0_seq1,451,41.4634,0.31093939,17,4,,6.00E-12,Q9R1K7,Tubulin delta chain (Delta-tubulin),Tubulin delta chain (Delta-tubulin),GO:0005525; GO:0003924; GO:0030154; GO:0005814; GO:0005737; GO:0005874; GO:0007017; GO:0007275; GO:0005634; GO:0051258; GO:0007283; GO:0005200,GTP binding; GTPase activity; cell differentiation; centriole; cytoplasm; microtubule; microtubule-based process; multicellular organismal development; nucleus; protein polymerization; spermatogenesis; structural constituent of cytoskeleton,PF00091;,,,,,,,,,TBD_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; microtubule-based process [GO:0007017]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp46667_c0_seq1,559,44.0072,0.4465724,17,6,,5.00E-33,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp46691_c0_seq1,344,44.7674,0.23469586,18,0,,,,,,,,,5.00E-14,CHOYP_LOC100367864.2.3,,,,,,,,, comp46719_c0_seq1,358,34.3575,0.59014159,7,18,,3.00E-25,Q9CXE7,Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2),Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2),GO:0005794; GO:0090161; GO:0005801; GO:0070971; GO:0005789; GO:0005793; GO:0033116; GO:0016021; GO:0015031,Golgi apparatus; Golgi ribbon formation; cis-Golgi network; endoplasmic reticulum exit site; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; protein transport,PF01105;,,,,,,,,,TMED5_MOUSE,Mus musculus (Mouse),Golgi ribbon formation [GO:0090161]; protein transport [GO:0015031] comp4677_c0_seq1,212,67.9245,0.99554309,0,3,,2.00E-22,P25539,Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (DRAP deaminase) (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)],Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (DRAP deaminase) (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)],GO:0008703; GO:0050661; GO:0008835; GO:0009231; GO:0008270,5-amino-6-(5-phosphoribosylamino)uracil reductase activity; NADP binding; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity; riboflavin biosynthetic process; zinc ion binding,PF00383;PF01872;,,,,,,,,,RIBD_ECOLI,Escherichia coli (strain K12),riboflavin biosynthetic process [GO:0009231]; RNA modification [GO:0009451] comp46781_c0_seq1,514,38.5214,0.57894956,28,0,,7.00E-10,Q8WUA8,Tsukushin (Tsukushi) (E2-induced gene 4 protein) (Leucine-rich repeat-containing protein 54),Tsukushin (Tsukushi) (E2-induced gene 4 protein) (Leucine-rich repeat-containing protein 54),GO:0021960; GO:0061073; GO:0021540; GO:0005615; GO:0021670; GO:0030178; GO:0010468,anterior commissure morphogenesis; ciliary body morphogenesis; corpus callosum morphogenesis; extracellular space; lateral ventricle development; negative regulation of Wnt receptor signaling pathway; regulation of gene expression,PF13855;,,,,,,,,,TSK_HUMAN,Homo sapiens (Human),anterior commissure morphogenesis [GO:0021960]; ciliary body morphogenesis [GO:0061073]; corpus callosum morphogenesis [GO:0021540]; lateral ventricle development [GO:0021670]; negative regulation of Wnt signaling pathway [GO:0030178]; regulation of gene expression [GO:0010468] comp46808_c0_seq1,258,42.2481,0.46920995,7,0,,,,,,,,,6.00E-18,CHOYP_DDHD1.1.1,,,,,,,,, comp46808_c1_seq1,301,47.5083,0.53190411,14,0,,5.00E-12,Q8NEL9,Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1),Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1),GO:0008219; GO:0005737; GO:0016787; GO:0016042; GO:0046872,cell death; cytoplasm; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;,,,,,,,,,DDHD1_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of mitochondrial fission [GO:0090141] comp46810_c0_seq1,275,55.6364,1.09525258,1,12,,2.00E-19,P64320,ATP-dependent DNA helicase UvrD2 (EC 3.6.4.12),,GO:0005524; GO:0004003; GO:0003677; GO:0003678; GO:0006281; GO:0008094; GO:0040007; GO:0005622; GO:0000287,ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA helicase activity; DNA repair; DNA-dependent ATPase activity; growth; intracellular; magnesium ion binding,,,,,,,,,,UVRD2_MYCTU,, comp46825_c0_seq1,393,55.2163,0.80340367,2,10,,8.00E-06,Q38ZZ5,Disulfide bond formation protein B 2 (Disulfide oxidoreductase 2),Disulfide bond formation protein B 2 (Disulfide oxidoreductase 2),GO:0009055; GO:0016021; GO:0005886; GO:0015035,electron carrier activity; integral to membrane; plasma membrane; protein disulfide oxidoreductase activity,PF02600;,,,,,,,,,DSBB2_BURS3,Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383), comp46838_c0_seq1,222,70.7207,1.12299225,0,10,,2.00E-08,P39376,HTH-type transcriptional regulator YjiE (Hypochlorite-response regulator protein YjiE) (Quorum-sensing regulator protein D),HTH-type transcriptional regulator YjiE (Hypochlorite-response regulator protein YjiE) (Quorum-sensing regulator protein D),GO:0001017; GO:0042802; GO:0006355; GO:0003700; GO:0000976; GO:0006351,"bacterial-type RNA polymerase regulatory region DNA binding; identical protein binding; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription regulatory region sequence-specific DNA binding; transcription, DNA-dependent",PF00126;PF03466;,,,,,,,,,YJIE_ECOLI,Escherichia coli (strain K12),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp46864_c0_seq1,283,45.583,1.21369037,3,15,,5.00E-15,Q9UBX5,Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50),Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50),GO:0005509; GO:0007160; GO:0005737; GO:0071953; GO:0048251; GO:0005615; GO:0005178; GO:0034394; GO:0005578; GO:0001558; GO:2000121,calcium ion binding; cell-matrix adhesion; cytoplasm; elastic fiber; elastic fiber assembly; extracellular space; integrin binding; protein localization to cell surface; proteinaceous extracellular matrix; regulation of cell growth; regulation of removal of superoxide radicals,PF12662;PF07645;,,,,,,,,,FBLN5_HUMAN,Homo sapiens (Human),cell-matrix adhesion [GO:0007160]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; protein localization to cell surface [GO:0034394]; regulation of cell growth [GO:0001558]; regulation of removal of superoxide radicals [GO:2000121]; secretion [GO:0046903] comp46877_c0_seq1,352,40.3409,0.56199459,3,7,,,,,,,,,4.00E-180,CHOYP_MTRNR2L14.1.2,,,,,,,,, comp4687_c0_seq1,326,47.2393,0.49671353,10,0,,2.00E-12,Q0PMG2,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0021799; GO:0001764,anchored to plasma membrane; cerebral cortex radially oriented cell migration; neuron migration,PF00629;,,,,,,,,,MDGA1_MOUSE,Mus musculus (Mouse),cerebral cortex radially oriented cell migration [GO:0021799]; neuron migration [GO:0001764] comp46887_c0_seq1,247,44.5344,0.53143728,3,7,,1.00E-06,Q8IUZ5,5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2),5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2),GO:0016829; GO:0008152; GO:0005739; GO:0030170; GO:0008483,lyase activity; metabolic process; mitochondrion; pyridoxal phosphate binding; transaminase activity,PF00202;,,,,,,,,,AT2L2_HUMAN,Homo sapiens (Human),collagen catabolic process [GO:0030574]; lysine catabolic process [GO:0006554] comp46892_c0_seq1,206,45.1456,1.07408191,2,0,,2.00E-08,Q7TT41,DBH-like monooxygenase protein 2 (EC 1.14.17.-) (Dopamine-beta-hydroxylase-like protein),DBH-like monooxygenase protein 2 (EC 1.14.17.-) (Dopamine-beta-hydroxylase-like protein),GO:0006584; GO:0005507; GO:0004500; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOXD2_MOUSE,Mus musculus (Mouse), comp46930_c0_seq1,270,47.4074,0.33284662,6,15,,4.00E-06,Q9V5N8,Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night),GO:0004930; GO:0007464; GO:0048057; GO:0016055; GO:0007411; GO:0005509; GO:0016339; GO:0050839; GO:0005911; GO:0048813; GO:0070593; GO:0007156; GO:0005887; GO:0016319; GO:0030178; GO:0007218; GO:0016318; GO:0030177; GO:0005057; GO:0050770; GO:0090175; GO:0051963; GO:0035159; GO:0007367; GO:0004888,"G-protein coupled receptor activity; R3/R4 cell fate commitment; R3/R4 development; Wnt receptor signaling pathway; axon guidance; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell-cell junction; dendrite morphogenesis; dendrite self-avoidance; homophilic cell adhesion; integral to plasma membrane; mushroom body development; negative regulation of Wnt receptor signaling pathway; neuropeptide signaling pathway; ommatidial rotation; positive regulation of Wnt receptor signaling pathway; receptor signaling protein activity; regulation of axonogenesis; regulation of establishment of planar polarity; regulation of synapse assembly; regulation of tube length, open tracheal system; segment polarity determination; transmembrane signaling receptor activity",PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,STAN_DROME,Drosophila melanogaster (Fruit fly),"axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]" comp46958_c0_seq1,285,74.386,1.11124527,0,12,,1.00E-21,P10503,Bifunctional protein PutA [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)],Bifunctional protein PutA [Includes: Proline dehydrogenase (EC 1.5.5.2) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)],GO:0003842; GO:0006537; GO:0016020; GO:0016620; GO:0006561; GO:0006562; GO:0010133; GO:0004657; GO:0043565; GO:0003700; GO:0006351,"1-pyrroline-5-carboxylate dehydrogenase activity; glutamate biosynthetic process; membrane; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; proline biosynthetic process; proline catabolic process; proline catabolic process to glutamate; proline dehydrogenase activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00171;PF01619;PF14850;,,,,,,,,,PUTA_SALTY,Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720),"oxidation-reduction process [GO:0055114]; proline biosynthetic process [GO:0006561]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; transcription, DNA-templated [GO:0006351]" comp46959_c1_seq1,228,61.4035,1.35534207,0,10,,2.00E-13,P29422,Catalase (EC 1.11.1.6),Catalase (EC 1.11.1.6),GO:0004096; GO:0005737; GO:0020037; GO:0042744; GO:0046872,catalase activity; cytoplasm; heme binding; hydrogen peroxide catabolic process; metal ion binding,PF00199;PF06628;,,,,,,,,,CATA_MICLU,Micrococcus luteus (Micrococcus lysodeikticus),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp46979_c0_seq1,247,44.9393,0.32979264,2,8,,8.00E-08,Q6A548,Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit),Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit),GO:0003677; GO:0016605; GO:0003723; GO:0006278; GO:0000781; GO:0005737; GO:0046872; GO:0005730; GO:0030529; GO:0003721,"DNA binding; PML body; RNA binding; RNA-dependent DNA replication; chromosome, telomeric region; cytoplasm; metal ion binding; nucleolus; ribonucleoprotein complex; telomeric template RNA reverse transcriptase activity",PF00078;PF12009;,,,,,,,,,TERT_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),telomere maintenance via telomerase [GO:0007004] comp46980_c0_seq1,285,41.0526,0.75264085,5,15,,,,,,,,,2.00E-24,CHOYP_PHUM_PHUM504500.1.1,,,,,,,,, comp46984_c0_seq1,643,46.1897,0.86025081,24,9,,1.00E-21,Q6ZRR9,Doublecortin domain-containing protein 5,Doublecortin domain-containing protein 5,GO:0035556,intracellular signal transduction,,1.00E-62,CHOYP_LOC100377058.1.1,,,,,,,DCDC5_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp46996_c0_seq1,231,37.6623,0.30130435,3,8,,,,,,,,,1.00E-13,CHOYP_MANSC1.1.1,,,,,,,,, comp47024_c0_seq1,206,42.7184,0.92412892,9,0,,1.00E-07,Q32LJ3,Uncharacterized protein CXorf65 homolog,Uncharacterized protein CXorf65 homolog,,,,,,,,,,,,CX065_BOVIN,Bos taurus (Bovine), comp47032_c0_seq1,283,44.8763,0.95897301,4,16,,3.00E-10,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp47096_c0_seq1,251,47.8088,0.5701448,9,8,,4.00E-16,Q6PCD5,E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201),E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201),GO:0006281; GO:0016605; GO:0005737; GO:0031571; GO:0005634; GO:0010212; GO:0004842; GO:0008270,DNA repair; PML body; cytoplasm; mitotic G1 DNA damage checkpoint; nucleus; response to ionizing radiation; ubiquitin-protein ligase activity; zinc ion binding,PF13639;,,,,,,,,,RFWD3_HUMAN,Homo sapiens (Human),DNA repair [GO:0006281]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mitotic G1 DNA damage checkpoint [GO:0031571]; positive regulation of defense response to virus by host [GO:0002230]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; xenophagy [GO:0098792] comp47103_c1_seq1,341,38.7097,0.6600553,5,11,,1.00E-13,Q91YU6,Leucine zipper putative tumor suppressor 2 (Protein LAPSER1),Leucine zipper putative tumor suppressor 2 (Protein LAPSER1),GO:0016055; GO:0051301; GO:0005737; GO:0005874; GO:0005815; GO:0007067,Wnt receptor signaling pathway; cell division; cytoplasm; microtubule; microtubule organizing center; mitosis,,2.00E-26,CHOYP_PROSAPIP1.1.1,,,,,,,LZTS2_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; kidney development [GO:0001822]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Wnt signaling pathway [GO:0030178]; nuclear export [GO:0051168]; positive regulation of cell death [GO:0010942]; renal system development [GO:0072001]; spindle midzone assembly [GO:0051255]; Wnt signaling pathway [GO:0016055] comp47108_c0_seq1,229,61.5721,1.13582413,0,13,,8.00E-29,P67126,UPF0051 protein Mb1496 [Cleaved into: Endonuclease PI-MtuHIIP (EC 3.1.-.-) (Mtu pps1 intein)],UPF0051 protein Mb1496 [Cleaved into: Endonuclease PI-MtuHIIP (EC 3.1.-.-) (Mtu pps1 intein)],GO:0004519; GO:0016539; GO:0006314; GO:0016226; GO:0090305,endonuclease activity; intein-mediated protein splicing; intron homing; iron-sulfur cluster assembly; nucleic acid phosphodiester bond hydrolysis,PF01458;,,,,,,,,,Y1496_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; iron-sulfur cluster assembly [GO:0016226] comp47134_c0_seq1,224,43.3036,0.67136888,9,0,,9.00E-16,Q61391,Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10),Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10),GO:0030424; GO:0050435; GO:0005903; GO:0071492; GO:0071493; GO:0071345; GO:0046449; GO:0030425; GO:0016021; GO:0001822; GO:0004222; GO:0044306; GO:0042277; GO:0005886; GO:0006508; GO:0090399; GO:0019233; GO:0008021; GO:0008270,axon; beta-amyloid metabolic process; brush border; cellular response to UV-A; cellular response to UV-B; cellular response to cytokine stimulus; creatinine metabolic process; dendrite; integral to membrane; kidney development; metalloendopeptidase activity; neuron projection terminus; peptide binding; plasma membrane; proteolysis; replicative senescence; sensory perception of pain; synaptic vesicle; zinc ion binding,PF01431;PF05649;,,,,,,,,,NEP_MOUSE,Mus musculus (Mouse),beta-amyloid metabolic process [GO:0050435]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233] comp47155_c0_seq1,261,45.5939,1.13323463,5,15,,5.00E-38,Q16975,Calcium-independent protein kinase C (EC 2.7.11.13) (APL II),Calcium-independent protein kinase C (EC 2.7.11.13) (APL II),GO:0005524; GO:0035556; GO:0016020; GO:0046872; GO:0004697,ATP binding; intracellular signal transduction; membrane; metal ion binding; protein kinase C activity,PF00130;PF00168;PF00069;PF00433;,4.00E-39,CHOYP_KPC2.3.3,,,,,,,KPC2_APLCA,Aplysia californica (California sea hare),intracellular signal transduction [GO:0035556] comp47157_c0_seq1,327,58.7156,0.99696981,2,13,,1.00E-15,Q82U73,Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase) (EC 2.4.2.-),Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase) (EC 2.4.2.-),GO:0016021; GO:0009252; GO:0009274; GO:0005886; GO:0008360; GO:0016763,"integral to membrane; peptidoglycan biosynthetic process; peptidoglycan-based cell wall; plasma membrane; regulation of cell shape; transferase activity, transferring pentosyl groups",PF00912;,,,,,,,,,MTGA_NITEU,Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298),cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp47167_c0_seq1,251,40.6375,0.40304518,6,4,,9.00E-07,Q9UGI0,Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1),Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1),GO:0070530; GO:0016055; GO:0016477; GO:0005737; GO:0007010; GO:0005634; GO:0030177; GO:0035523; GO:1990168; GO:0070536; GO:0071947; GO:0022604; GO:0004221; GO:0004843; GO:0008270,K63-linked polyubiquitin binding; Wnt receptor signaling pathway; cell migration; cytoplasm; cytoskeleton organization; nucleus; positive regulation of Wnt receptor signaling pathway; protein K29-linked deubiquitination; protein K33-linked deubiquitination; protein K63-linked deubiquitination; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of cell morphogenesis; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding,PF02338;PF00641;,,,,,,,,,ZRAN1_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] comp47179_c0_seq2,880,37.6136,0.45040958,8,14,,8.00E-42,Q9XYM0,Adapter molecule Crk,Adapter molecule Crk,GO:0005070; GO:0007298; GO:0048013; GO:0046529; GO:0007520; GO:0046330; GO:0032319; GO:0032956,"SH3/SH2 adaptor activity; border follicle cell migration; ephrin receptor signaling pathway; imaginal disc fusion, thorax closure; myoblast fusion; positive regulation of JNK cascade; regulation of Rho GTPase activity; regulation of actin cytoskeleton organization",PF00017;PF00018;PF07653;,8.00E-17,CHOYP_PHUM_PHUM332570.1.1,,,,,,,CRK_DROME,Drosophila melanogaster (Fruit fly),"border follicle cell migration [GO:0007298]; ephrin receptor signaling pathway [GO:0048013]; imaginal disc fusion, thorax closure [GO:0046529]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of JNK cascade [GO:0046330]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]" comp47203_c0_seq1,266,49.2481,0.81480025,0,12,,4.00E-08,O95714,E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2),GO:0006281; GO:0032183; GO:0005814; GO:0005737; GO:0005085; GO:0020037; GO:0006886; GO:0005634; GO:0042787; GO:0004842; GO:0008270,DNA repair; SUMO binding; centriole; cytoplasm; guanyl-nucleotide exchange factor activity; heme binding; intracellular protein transport; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;,,,,,,,,,HERC2_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283] comp47209_c0_seq1,296,48.3108,0.49438767,2,12,,3.00E-38,A1K5T6,UPF0061 protein azo1574,UPF0061 protein azo1574,,,PF02696;,9.00E-36,CHOYP_LOC100371716.1.1,,,,,,,Y1574_AZOSB,Azoarcus sp. (strain BH72), comp47211_c0_seq1,246,44.3089,0.59335229,6,3,,1.00E-11,P57760,Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2),Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2),GO:0005524; GO:0005798; GO:0001077; GO:0071560; GO:0016020; GO:0004715; GO:0048471; GO:0046777; GO:0004672; GO:0004674,ATP binding; Golgi-associated vesicle; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cellular response to transforming growth factor beta stimulus; membrane; non-membrane spanning protein tyrosine kinase activity; perinuclear region of cytoplasm; protein autophosphorylation; protein kinase activity; protein serine/threonine kinase activity,PF00069;,6.00E-12,CHOYP_LOC100745596.1.1,,,,,,,STK16_RAT,Rattus norvegicus (Rat),cellular response to transforming growth factor beta stimulus [GO:0071560]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777] comp47237_c1_seq1,250,44.8,0.32180002,1,10,,3.00E-31,Q2TA25,Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1),Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1),GO:0005524; GO:0031572; GO:0000086; GO:0007092; GO:0005813; GO:0051297; GO:0000942; GO:0000910; GO:0005737; GO:0000776; GO:0008017; GO:0001578; GO:0030496; GO:0000070; GO:0007094; GO:0043066; GO:0045736; GO:0000122; GO:0005634; GO:0018105; GO:0010800; GO:0031648; GO:0071168; GO:0004674; GO:0016567; GO:0043393; GO:0005876; GO:0051233; GO:0000922,ATP binding; G2 DNA damage checkpoint; G2/M transition of mitotic cell cycle; activation of mitotic anaphase-promoting complex activity; centrosome; centrosome organization; condensed nuclear chromosome outer kinetochore; cytokinesis; cytoplasm; kinetochore; microtubule binding; microtubule bundle formation; midbody; mitotic sister chromatid segregation; mitotic spindle assembly checkpoint; negative regulation of apoptotic process; negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of transcription from RNA polymerase II promoter; nucleus; peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; protein destabilization; protein localization to chromatin; protein serine/threonine kinase activity; protein ubiquitination; regulation of protein binding; spindle microtubule; spindle midzone; spindle pole,PF00069;PF00659;,8.00E-23,CHOYP_LOC584420.1.1,,,,,,,PLK1_BOVIN,Bos taurus (Bovine),centrosome organization [GO:0051297]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; G2 DNA damage checkpoint [GO:0031572]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; synaptonemal complex disassembly [GO:0070194] comp47240_c0_seq1,255,43.1373,0.17204566,3,3,,1.00E-26,A4IGH2,"Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (EC 1.3.99.-) (Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1)","Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (EC 1.3.99.-) (Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1)",GO:0051539; GO:0004109; GO:0046872; GO:0005739; GO:0006779,"4 iron, 4 sulfur cluster binding; coproporphyrinogen oxidase activity; metal ion binding; mitochondrion; porphyrin-containing compound biosynthetic process",PF06969;PF04055;,,,,,,,,,RSAD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),porphyrin-containing compound biosynthetic process [GO:0006779] comp47259_c0_seq1,437,34.0961,0.86811265,16,6,,8.00E-11,Q9ESN6,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2) (Neural activity-related RING finger protein),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2) (Neural activity-related RING finger protein),GO:0005737; GO:0017022; GO:0043523; GO:0004842; GO:0008270,cytoplasm; myosin binding; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_MOUSE,Mus musculus (Mouse),regulation of neuron apoptotic process [GO:0043523] comp47266_c0_seq1,280,46.4286,0.21075269,8,11,,2.00E-24,A2AV36,Protein arginine N-methyltransferase 7 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT7) (EC 2.1.1.125) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) (EC 2.1.1.126),Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7),GO:0043046; GO:0016277; GO:0030154; GO:0005829; GO:0044020; GO:0005634; GO:0035243; GO:0006349; GO:0006355; GO:0000387; GO:0006351,"DNA methylation involved in gamete generation; [myelin basic protein]-arginine N-methyltransferase activity; cell differentiation; cytosol; histone methyltransferase activity (H4-R3 specific); nucleus; protein-arginine omega-N symmetric methyltransferase activity; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; spliceosomal snRNP assembly; transcription, DNA-dependent",,2.00E-24,CHOYP_LOC100867962.1.1,,,,,,,ANM7_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]; transcription, DNA-templated [GO:0006351]" comp47275_c0_seq1,652,42.638,0.77879364,16,17,,8.00E-11,Q55E58,Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),GO:0005524; GO:0005525; GO:0042641; GO:0000281; GO:0004721; GO:0006470; GO:0004674; GO:0007264,ATP binding; GTP binding; actomyosin; mitotic cytokinesis; phosphoprotein phosphatase activity; protein dephosphorylation; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF16095;PF06602;PF07714;PF08477;,,,,,,,,,PATS1_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176] comp47296_c0_seq1,269,34.5725,0.50420865,5,4,,,,,,,,,,,2.00E-15,ruditapes_c27988,,,,,,, comp47355_c0_seq1,311,64.3087,1.04001075,0,15,,9.00E-42,A0JYN1,Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37),Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37),GO:0005737; GO:0006782; GO:0004853,cytoplasm; protoporphyrinogen IX biosynthetic process; uroporphyrinogen decarboxylase activity,PF01208;,,,,,,,,,DCUP_ARTS2,Arthrobacter sp. (strain FB24),protoporphyrinogen IX biosynthetic process [GO:0006782] comp47356_c0_seq1,296,59.7973,0.9874793,0,14,,2.00E-28,Q894M8,Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase),Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase),GO:0030170; GO:0009034,pyridoxal phosphate binding; tryptophanase activity,PF01212;,,,,,,,,,TNAA_CLOTE,Clostridium tetani (strain Massachusetts / E88), comp47416_c1_seq1,508,45.8661,0.33933465,7,29,,,,,,,,,3.00E-13,CHOYP_LOC100378520.1.2,,,,,,,,, comp47441_c0_seq1,249,46.5863,0.60332798,6,5,,9.00E-17,P39770,Homeotic protein spalt-major,Homeotic protein spalt-major,GO:0003677; GO:0045466; GO:0045465; GO:0048098; GO:0046845; GO:0007427; GO:0008586; GO:0030539; GO:0008584; GO:0046872; GO:0048644; GO:0045892; GO:0035310; GO:0005634; GO:0007438; GO:0042659; GO:0007605; GO:0007525; GO:0035277; GO:0006351,"DNA binding; R7 cell differentiation; R8 cell differentiation; antennal joint development; branched duct epithelial cell fate determination, open tracheal system; epithelial cell migration, open tracheal system; imaginal disc-derived wing vein morphogenesis; male genitalia development; male gonad development; metal ion binding; muscle organ morphogenesis; negative regulation of transcription, DNA-dependent; notum cell fate specification; nucleus; oenocyte development; regulation of cell fate specification; sensory perception of sound; somatic muscle development; spiracle morphogenesis, open tracheal system; transcription, DNA-dependent",PF00096;,,,,,,,,,SALM_DROME,Drosophila melanogaster (Fruit fly),"antennal joint development [GO:0048098]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; epithelial cell migration, open tracheal system [GO:0007427]; glial cell development [GO:0021782]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; muscle organ morphogenesis [GO:0048644]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription, DNA-templated [GO:0045892]; notum cell fate specification [GO:0035310]; oenocyte development [GO:0007438]; open tracheal system development [GO:0007424]; R7 cell differentiation [GO:0045466]; R8 cell differentiation [GO:0045465]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell fate specification [GO:0042659]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; somatic muscle development [GO:0007525]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]" comp47456_c0_seq1,205,46.3415,1.09674305,0,5,,4.00E-11,Q6IMI4,Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2),Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,,,,,,,,,ST6B1_HUMAN,Homo sapiens (Human), comp47511_c0_seq2,227,40.5286,0,6,0,,6.00E-09,P09933,Thyroid peroxidase (TPO) (EC 1.11.1.8),Thyroid peroxidase (TPO) (EC 1.11.1.8),GO:0005509; GO:0020037; GO:0042446; GO:0042744; GO:0016021; GO:0004447; GO:0006590,calcium ion binding; heme binding; hormone biosynthetic process; hydrogen peroxide catabolic process; integral to membrane; iodide peroxidase activity; thyroid hormone generation,PF03098;PF00084;,,,,,,,,,PERT_PIG,Sus scrofa (Pig),hormone biosynthetic process [GO:0042446]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590] comp47519_c0_seq1,441,38.0952,0.57761296,18,0,,3.00E-19,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp47584_c0_seq1,226,43.3628,0.56751111,3,6,,2.00E-25,Q6GMF8,Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1),Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1),GO:0000139; GO:0016477; GO:0008283; GO:0005789; GO:0016021; GO:0050709; GO:0015031; GO:0006508; GO:0042058; GO:0061136; GO:0004252,Golgi membrane; cell migration; cell proliferation; endoplasmic reticulum membrane; integral to membrane; negative regulation of protein secretion; protein transport; proteolysis; regulation of epidermal growth factor receptor signaling pathway; regulation of proteasomal protein catabolic process; serine-type endopeptidase activity,PF01694;PF12595;,,,,,,,,,RHDF1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] comp47601_c0_seq1,258,39.5349,0.49865978,3,6,,2.00E-13,Q8AYS7,Centromere protein I (CENP-I),Centromere protein I (CENP-I),GO:0034508; GO:0000776; GO:0005634,centromere complex assembly; kinetochore; nucleus,PF07778;,,,,,,,,,CENPI_CHICK,Gallus gallus (Chicken),centromere complex assembly [GO:0034508] comp47614_c0_seq1,249,57.4297,1.07718149,0,15,,2.00E-29,Q8FDQ2,Arabinose 5-phosphate isomerase KpsF (API) (EC 5.3.1.13) (K-antigen-specific arabinose 5-phosphate isomerase) (K-API),Arabinose 5-phosphate isomerase KpsF (API) (EC 5.3.1.13) (K-antigen-specific arabinose 5-phosphate isomerase) (K-API),GO:0005524; GO:0019146; GO:0030246; GO:0009103; GO:0046872,ATP binding; arabinose-5-phosphate isomerase activity; carbohydrate binding; lipopolysaccharide biosynthetic process; metal ion binding,PF00571;PF01380;,,,,,,,,,KPSF_ECOL6,Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC),lipopolysaccharide biosynthetic process [GO:0009103] comp47617_c0_seq1,374,43.0481,0.58139951,13,44,,8.00E-41,Q5R5W9,UPF0489 protein C5orf22 homolog,UPF0489 protein C5orf22 homolog,,,PF12640;,3.00E-12,CHOYP_LOC101381408.1.1,2.00E-18,ruditapes_c13603,,,,,CE022_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp47656_c0_seq1,237,45.1477,1.01783708,10,0,,7.00E-11,Q4R7U3,Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase),Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase),GO:0005524; GO:0004351; GO:0004356; GO:0006542; GO:0005739,ATP binding; glutamate decarboxylase activity; glutamate-ammonia ligase activity; glutamine biosynthetic process; mitochondrion,PF00120;PF03951;,,,,,,,,,GLNA_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),glutamine biosynthetic process [GO:0006542] comp47702_c0_seq1,304,40.7895,0.83608361,0,15,,7.00E-06,Q575S8,Cytoglobin-2,Cytoglobin-2,GO:0005737; GO:0020037; GO:0005506; GO:0019825; GO:0005344,cytoplasm; heme binding; iron ion binding; oxygen binding; oxygen transporter activity,PF00042;,,,,,,,,,CYGB2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp47731_c0_seq1,272,35.2941,1.19319795,1,13,,2.00E-22,Q6AX44,Fibrinogen C domain-containing protein 1-A,Fibrinogen C domain-containing protein 1-A,GO:0008061; GO:0016021; GO:0046872,chitin binding; integral to membrane; metal ion binding,PF00147;,,,,,,,,,FBCDA_XENLA,Xenopus laevis (African clawed frog), comp47756_c0_seq1,257,60.3113,1.03098464,2,8,,5.00E-36,P64326,Transcription-repair-coupling factor (TRCF) (EC 3.6.4.-),,GO:0005524; GO:0008026; GO:0006281; GO:0005829; GO:0003684; GO:0005886,ATP binding; ATP-dependent helicase activity; DNA repair; cytosol; damaged DNA binding; plasma membrane,,,,,,,,,,MFD_MYCTU,, comp47759_c0_seq1,568,38.2042,0.45837951,30,2,,5.00E-23,Q2VUH7,Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1),Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1),GO:0043679; GO:0043010; GO:0060070; GO:0005938; GO:0007049; GO:0021695; GO:0021799; GO:0005829; GO:0005925; GO:0030900; GO:0021869; GO:0043015; GO:0031435; GO:0045665; GO:0043025; GO:0046330; GO:0050772; GO:0090263; GO:0043234; GO:0032956; GO:0070507; GO:0004871,axon terminus; camera-type eye development; canonical Wnt receptor signaling pathway; cell cortex; cell cycle; cerebellar cortex development; cerebral cortex radially oriented cell migration; cytosol; focal adhesion; forebrain development; forebrain ventricular zone progenitor cell division; gamma-tubulin binding; mitogen-activated protein kinase kinase kinase binding; negative regulation of neuron differentiation; neuronal cell body; positive regulation of JNK cascade; positive regulation of axonogenesis; positive regulation of canonical Wnt receptor signaling pathway; protein complex; regulation of actin cytoskeleton organization; regulation of microtubule cytoskeleton organization; signal transducer activity,PF00307;PF00778;,,,,,,,,,DIXC1_RAT,Rattus norvegicus (Rat),canonical Wnt signaling pathway [GO:0060070]; cerebellar cortex development [GO:0021695]; positive regulation of axonogenesis [GO:0050772]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330] comp47791_c0_seq1,396,46.7172,0.37515004,12,15,,9.00E-66,B4KD90,Glutamate [NMDA] receptor subunit 1,Glutamate [NMDA] receptor subunit 1,GO:0017146; GO:0055074; GO:0030054; GO:0005234; GO:0004970; GO:0007616; GO:0008355; GO:0014069; GO:0045211; GO:0042391; GO:0007268,N-methyl-D-aspartate selective glutamate receptor complex; calcium ion homeostasis; cell junction; extracellular-glutamate-gated ion channel activity; ionotropic glutamate receptor activity; long-term memory; olfactory learning; postsynaptic density; postsynaptic membrane; regulation of membrane potential; synaptic transmission,PF01094;PF10562;PF00060;PF10613;,2.00E-70,CHOYP_LOC100533321.1.1,,,,,,,NMDA1_DROMO,Drosophila mojavensis (Fruit fly),calcium ion homeostasis [GO:0055074]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term memory [GO:0007616]; olfactory learning [GO:0008355]; regulation of membrane potential [GO:0042391] comp47845_c0_seq1,228,52.193,0.58719078,5,4,,,,,,,,,3.00E-27,CHOYP_LOC100368368.1.1,,,,,,,,, comp47846_c0_seq1,327,46.4832,0.5220208,6,28,,2.00E-07,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp4786_c1_seq1,426,41.0798,0.79707106,12,0,,2.00E-47,Q27256,Protein white,Protein white,GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0031409; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; pigment binding; transport,PF01061;PF00005;,7.00E-39,CHOYP_LOC100374352.1.3,,,,,,,WHITE_ANOGA,Anopheles gambiae (African malaria mosquito),eye pigment precursor transport [GO:0006856]; ommochrome biosynthetic process [GO:0006727] comp47870_c0_seq1,257,37.3541,0.67217692,6,0,,1.00E-16,Q562C6,Leucine zipper transcription factor-like protein 1,Leucine zipper transcription factor-like protein 1,GO:0005737; GO:0072594,cytoplasm; establishment of protein localization to organelle,,5.00E-26,CHOYP_BRAFLDRAFT_268354.1.1,,,,,,,LZTL1_RAT,Rattus norvegicus (Rat),negative regulation of protein localization to ciliary membrane [GO:1903568] comp47915_c0_seq1,237,41.7722,0.3976679,5,0,,1.00E-24,Q8R420,ATP-binding cassette sub-family A member 3,ATP-binding cassette sub-family A member 3,GO:0005524; GO:0006200; GO:0016887; GO:0097233; GO:0016021; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; alveolar lamellar body membrane; integral to membrane; plasma membrane; transport,PF00005;,2.00E-18,CHOYP_TRIADDRAFT_53677.1.1,,,,,,,ABCA3_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810] comp47928_c0_seq1,214,52.8037,1.08794279,0,7,,2.00E-08,P23888,Polysialic acid transport ATP-binding protein KpsT,Polysialic acid transport ATP-binding protein KpsT,GO:0005524; GO:0006200; GO:0016887; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; plasma membrane; transport,PF00005;,,,,,,,,,KPST1_ECOLX,Escherichia coli,transport [GO:0006810] comp47956_c0_seq1,1948,32.8542,0.45681484,22916,65682,,5.00E-33,Q5RAZ9,60S ribosomal protein L36,60S ribosomal protein L36,GO:0022625; GO:0005730; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; nucleolus; structural constituent of ribosome; translation,PF01158;,2.00E-34,CHOYP_RL36.8.8,7.00E-64,ruditapes_lrc11074,,,,,RL36_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),translation [GO:0006412] comp47992_c0_seq1,214,37.8505,0.7924006,1,9,,3.00E-14,Q13360,Zinc finger protein 177,Zinc finger protein 177,GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN177_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp48052_c0_seq1,573,45.7243,0.50528323,35602,116234,,1.00E-87,Q1HR24,40S ribosomal protein S14,40S ribosomal protein S14,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00411;,2.00E-124,CHOYP_ZSWM8.1.1,1.00E-124,ruditapes2_lrc4878,,,,,RS14_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),translation [GO:0006412] comp48055_c0_seq1,495,36.5657,0.48520619,23499,44051,,2.00E-19,Q8HXB8,60S ribosomal protein L29,60S ribosomal protein L29,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01779;,3.00E-25,CHOYP_SMP_066940.5.11,3.00E-30,ruditapes2_c886,,,,,RL29_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),translation [GO:0006412] comp48058_c0_seq1,642,41.9003,0.57289369,82912,185155,,8.00E-98,Q90YV7,60S ribosomal protein L11,60S ribosomal protein L11,GO:0005730; GO:0034504; GO:0019843; GO:0005840; GO:0003735; GO:0006412,nucleolus; protein localization to nucleus; rRNA binding; ribosome; structural constituent of ribosome; translation,PF00281;PF00673;,2.00E-110,CHOYP_RL11.2.7,2.00E-135,ruditapes_lrc33892,,,,,RL11_ICTPU,Ictalurus punctatus (Channel catfish) (Silurus punctatus),protein localization to nucleus [GO:0034504]; translation [GO:0006412] comp48116_c0_seq1,548,42.8832,0.51702577,45025,114657,,3.00E-57,Q56K03,60S ribosomal protein L27a,60S ribosomal protein L27a,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00828;,4.00E-100,CHOYP_RS4.3.11,5.00E-103,ruditapes2_c58,,,,,RL27A_BOVIN,Bos taurus (Bovine),translation [GO:0006412] comp48128_c0_seq1,224,44.6429,0.45455451,3929,10012,,2.00E-21,Q8SWD4,Ubiquitin,Ubiquitin,GO:0005737; GO:0005634,cytoplasm; nucleus,PF00240;,7.00E-42,CHOYP_LOC100695843.4.4,3.00E-44,ruditapes_lrc22398,,,,,UBIQ_ENCCU,Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite), comp48128_c1_seq1,362,41.989,0.31510657,28043,61274,,2.00E-58,P18101,Ubiquitin-60S ribosomal protein L40 (CEP52) [Cleaved into: Ubiquitin; 60S ribosomal protein L40],Ubiquitin-60S ribosomal protein L40 (CEP52) [Cleaved into: Ubiquitin; 60S ribosomal protein L40],GO:0006464; GO:0022625; GO:0005875; GO:0005634; GO:0003735; GO:0006412; GO:0006511,cellular protein modification process; cytosolic large ribosomal subunit; microtubule associated complex; nucleus; structural constituent of ribosome; translation; ubiquitin-dependent protein catabolic process,PF01020;PF00240;,1.00E-85,CHOYP_LOC101209425.2.2,1.00E-82,ruditapes2_lrc5109,,,,,RL40_DROME,Drosophila melanogaster (Fruit fly),cellular protein modification process [GO:0006464]; Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]; translation [GO:0006412]; ubiquitin-dependent protein catabolic process [GO:0006511] comp48129_c0_seq1,895,38.5475,0.63247138,44753,121588,,1.00E-51,P83732,60S ribosomal protein L24 (L30),60S ribosomal protein L24 (L30),GO:0022625; GO:0003735; GO:0006412,cytosolic large ribosomal subunit; structural constituent of ribosome; translation,PF01246;,3.00E-60,CHOYP_BRAFLDRAFT_273508.3.4,1.00E-125,ruditapes_c34139,,,,,RL24_RAT,Rattus norvegicus (Rat),assembly of large subunit precursor of preribosome [GO:1902626]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp48148_c0_seq1,522,44.4444,0.70385305,49353,126862,,1.00E-51,O46160,60S ribosomal protein L14,60S ribosomal protein L14,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01929;,2.00E-27,CHOYP_RL14.7.9,8.00E-69,ruditapes_lrc13269,,,,,RL14_LUMRU,Lumbricus rubellus (Humus earthworm),translation [GO:0006412] comp48159_c0_seq1,343,35.277,1.05995299,12852,424,,,,,,,,,,,5.00E-25,ruditapes_c8977,,,,,,, comp48169_c0_seq1,529,38.1853,0.72852494,54474,75049,,1.00E-62,Q9IA76,60S ribosomal protein L31,60S ribosomal protein L31,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01198;,2.00E-97,CHOYP_LOC100180716.1.2,6.00E-83,ruditapes2_c157,,,,,RL31_PAROL,Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus),translation [GO:0006412] comp48171_c0_seq1,667,43.7781,0.75384568,64909,183355,,1.00E-92,Q0PXY6,60S ribosomal protein L18,60S ribosomal protein L18,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF17135;,5.00E-88,CHOYP_RL18.2.2,1.00E-124,ruditapes2_c5058,,,,,RL18_DIACI,Diaphorina citri (Asian citrus psyllid),translation [GO:0006412] comp48177_c0_seq1,446,42.8251,0.54572971,24,39,,5.00E-59,O02373,UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Protein sugarless) (Protein suppenkasper),UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Protein sugarless) (Protein suppenkasper),GO:0051287; GO:0003979; GO:0006065; GO:0016055; GO:0030206; GO:0007427; GO:0008543; GO:0007507; GO:0015014; GO:0007476; GO:0002121; GO:0007509; GO:0016319; GO:0042048; GO:0007428; GO:0007367; GO:0007224,"NAD binding; UDP-glucose 6-dehydrogenase activity; UDP-glucuronate biosynthetic process; Wnt receptor signaling pathway; chondroitin sulfate biosynthetic process; epithelial cell migration, open tracheal system; fibroblast growth factor receptor signaling pathway; heart development; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; imaginal disc-derived wing morphogenesis; inter-male aggressive behavior; mesoderm migration involved in gastrulation; mushroom body development; olfactory behavior; primary branching, open tracheal system; segment polarity determination; smoothened signaling pathway",PF00984;PF03720;PF03721;,8.00E-39,CHOYP_BRAFLDRAFT_126506.1.1,,,,,,,UGDH_DROME,Drosophila melanogaster (Fruit fly),"carbohydrate metabolic process [GO:0005975]; cell surface receptor signaling pathway [GO:0007166]; chondroitin sulfate biosynthetic process [GO:0030206]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; mesoderm migration involved in gastrulation [GO:0007509]; mushroom body development [GO:0016319]; olfactory behavior [GO:0042048]; primary branching, open tracheal system [GO:0007428]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; UDP-glucuronate biosynthetic process [GO:0006065]; Wnt signaling pathway [GO:0016055]" comp48206_c0_seq1,220,39.5455,0.3508009,6,0,,,,,,,,,2.00E-17,CHOYP_IAV.1.1,,,,,,,,, comp48214_c0_seq1,491,41.7515,0.65575291,57640,88380,,4.00E-64,P58375,60S ribosomal protein L30,60S ribosomal protein L30,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01248;,2.00E-85,CHOYP_DC1I2.2.3,3.00E-92,ruditapes_lrc34197,,,,,RL30_SPOFR,Spodoptera frugiperda (Fall armyworm),translation [GO:0006412] comp48215_c0_seq1,225,39.1111,0.58368922,3,4,,4.00E-10,E7FCN8,Protein inturned (Inturned planar cell polarity effector homolog),Protein inturned (Inturned planar cell polarity effector homolog),GO:0009986; GO:0042384; GO:0005737; GO:0060173; GO:0007399; GO:0008589,cell surface; cilium assembly; cytoplasm; limb development; nervous system development; regulation of smoothened signaling pathway,,,,,,,,,,INTU_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; limb development [GO:0060173]; nervous system development [GO:0007399]; regulation of smoothened signaling pathway [GO:0008589] comp48233_c0_seq1,892,43.0493,0.73061071,69558,207874,,5.00E-108,Q9BMX5,40S ribosomal protein S6,40S ribosomal protein S6,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01092;,4.00E-97,CHOYP_RS6.7.12,1.00E-163,ruditapes2_c1043,,,,,RS6_APLCA,Aplysia californica (California sea hare),translation [GO:0006412] comp48239_c0_seq1,657,40.1826,0.41542885,64978,151226,,2.00E-63,P62752,60S ribosomal protein L23a,60S ribosomal protein L23a,GO:0008283; GO:0022625; GO:0000166; GO:0005634; GO:0019843; GO:0003735; GO:0006412,cell proliferation; cytosolic large ribosomal subunit; nucleotide binding; nucleus; rRNA binding; structural constituent of ribosome; translation,PF00276;PF03939;,2.00E-74,CHOYP_RL23A.3.6,3.00E-119,ruditapes_lrc34507,,,,,RL23A_RAT,Rattus norvegicus (Rat),ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] comp48241_c0_seq1,264,45.0758,0.07528517,8,0,,4.00E-08,Q8QFV0,Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,,,,,,,,,KCNT1_CHICK,Gallus gallus (Chicken), comp48259_c0_seq1,471,38.6412,0.17353019,19,67,,5.00E-41,Q86Y56,HEAT repeat-containing protein 2,"Dynein assembly factor 5, axonemal (HEAT repeat-containing protein 2)",GO:0005737,cytoplasm,PF02985;,1.00E-36,CHOYP_BRAFLDRAFT_64948.1.1,,,,,,,HEAT2_HUMAN,Homo sapiens (Human),cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158] comp4825_c0_seq2,340,38.2353,0.32314897,5,0,,5.00E-06,P31795,Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN)] (Fragment),Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (Fragment),GO:0015074; GO:0006310; GO:0003964; GO:0075713; GO:0003676; GO:0090305; GO:0004523; GO:0046718,DNA integration; DNA recombination; RNA-directed DNA polymerase activity; establishment of integrated proviral latency; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; viral entry into host cell,PF00075;PF00665;,,,,,,,,,POL_MLVRK,Radiation murine leukemia virus (strain Kaplan),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp48332_c0_seq1,582,41.4089,0.7725647,10,1021,female>male,6.00E-15,Q9DGJ3,Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog),Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog),GO:0008203; GO:0005783; GO:0005576,cholesterol metabolic process; endoplasmic reticulum; extracellular region,PF02221;,,,1.00E-42,ruditapes_lrc32645,,,,,NPC2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cholesterol metabolic process [GO:0008203] comp48342_c1_seq1,278,48.2014,0.9535325,2,8,,3.00E-16,Q6NP60,MOXD1 homolog 2,MOXD1 homolog 2,GO:0006584; GO:0005507; GO:0004500; GO:0005615; GO:0016021,catecholamine metabolic process; copper ion binding; dopamine beta-monooxygenase activity; extracellular space; integral to membrane,PF03712;PF01082;PF03351;,,,,,,,,,MOX12_DROME,Drosophila melanogaster (Fruit fly), comp48382_c0_seq1,1977,37.9868,0.58816548,18535,92370,,1.00E-43,Q99020,Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A),Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A),GO:0003677; GO:0003723; GO:0005737; GO:0001837; GO:0000166; GO:0005634; GO:0045893; GO:0030529; GO:0006351,"DNA binding; RNA binding; cytoplasm; epithelial to mesenchymal transition; nucleotide binding; nucleus; positive regulation of transcription, DNA-dependent; ribonucleoprotein complex; transcription, DNA-dependent",PF08143;PF00076;,,,2.00E-77,ruditapes2_c681,,,,,ROAA_MOUSE,Mus musculus (Mouse),"epithelial to mesenchymal transition [GO:0001837]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp48392_c0_seq1,228,64.0351,1.03213253,1,5,,4.00E-06,Q58288,Uncharacterized lipoprotein MJ0878,Uncharacterized lipoprotein MJ0878,GO:0005886,plasma membrane,PF01497;,,,,,,,,,Y878_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),transport [GO:0006810] comp48402_c0_seq1,1285,44.4358,0.31751538,70,111,,1.00E-31,O00268,Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135),Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135),GO:0003677; GO:0071339; GO:0005737; GO:0019048; GO:0001541; GO:0045893; GO:0006357; GO:0003700; GO:0003713; GO:0006368; GO:0005669; GO:0033276; GO:0006367; GO:0016032,"DNA binding; MLL1 complex; cytoplasm; modulation by virus of host morphology or physiology; ovarian follicle development; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription elongation from RNA polymerase II promoter; transcription factor TFIID complex; transcription factor TFTC complex; transcription initiation from RNA polymerase II promoter; viral process",PF05236;PF07531;,1.00E-47,CHOYP_SI_DKEY-219C3.2.1.1,,,,,,,TAF4_HUMAN,Homo sapiens (Human),"DNA-templated transcription, initiation [GO:0006352]; ovarian follicle development [GO:0001541]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp48419_c0_seq1,316,39.557,0.49224095,14,0,,2.00E-13,Q9Y5W7,Sorting nexin-14,Sorting nexin-14,GO:0007154; GO:0016021; GO:0035091; GO:0015031; GO:0038032,cell communication; integral to membrane; phosphatidylinositol binding; protein transport; termination of G-protein coupled receptor signaling pathway,PF08628;PF00787;PF02194;PF00615;,3.00E-11,CHOYP_BRAFLDRAFT_275391.1.1,,,,,,,SNX14_HUMAN,Homo sapiens (Human),autophagosome maturation [GO:0097352]; protein transport [GO:0015031] comp48421_c0_seq1,835,38.4431,0.5969542,22286,18899,,5.00E-64,P08991,Histone H2A.V (H2A.F/Z) (Fragment),Histone H2A.V (H2A.F/Z) (Fragment),GO:0003677; GO:0000786; GO:0006334; GO:0005634,DNA binding; nucleosome; nucleosome assembly; nucleus,PF00125;PF16211;,4.00E-103,CHOYP_H2AV.4.7,3.00E-133,ruditapes2_lrc3839,1.00E-102,BQ427163.p.cg.6,8,,H2AV_STRPU,Strongylocentrotus purpuratus (Purple sea urchin),chromatin silencing [GO:0006342] comp48459_c0_seq1,475,41.2632,0.84335965,46903,147448,,7.00E-61,P17078,60S ribosomal protein L35,60S ribosomal protein L35,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00831;,2.00E-58,CHOYP_RL35.1.4,6.00E-89,ruditapes_c422,,,,,RL35_RAT,Rattus norvegicus (Rat),"cellular response to UV-B [GO:0071493]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; translation [GO:0006412]" comp48465_c0_seq1,299,44.8161,0.67205053,1,5,,8.00E-26,Q8MLZ5,Ras GTPase-activating protein gap-2 (GTPase-activating protein 2),Ras GTPase-activating protein gap-2 (GTPase-activating protein 2),GO:0005099; GO:0005737; GO:0031235; GO:0046580; GO:0005543; GO:0007165,Ras GTPase activator activity; cytoplasm; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; phospholipid binding; signal transduction,PF00168;PF00616;,3.00E-41,CHOYP_NGAP.1.2,,,,,,,GAP2_CAEEL,Caenorhabditis elegans,associative learning [GO:0008306]; long-term memory [GO:0007616]; negative regulation of Ras protein signal transduction [GO:0046580]; short-term memory [GO:0007614]; signal transduction [GO:0007165] comp48479_c0_seq1,510,47.451,1.12991037,4,96,,1.00E-09,Q9D0L6,BMP and activin membrane-bound inhibitor homolog (Putative transmembrane protein NMA),BMP and activin membrane-bound inhibitor homolog (Putative transmembrane protein NMA),GO:0016477; GO:0005737; GO:0016021; GO:0016020; GO:0030512; GO:0005886; GO:0090263; GO:0035413; GO:0008284; GO:0010718; GO:0032092; GO:0045893; GO:0008360; GO:0007179,"cell migration; cytoplasm; integral to membrane; membrane; negative regulation of transforming growth factor beta receptor signaling pathway; plasma membrane; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of catenin import into nucleus; positive regulation of cell proliferation; positive regulation of epithelial to mesenchymal transition; positive regulation of protein binding; positive regulation of transcription, DNA-dependent; regulation of cell shape; transforming growth factor beta receptor signaling pathway",PF06211;,,,,,,,,,BAMBI_MOUSE,Mus musculus (Mouse),"cell migration [GO:0016477]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell shape [GO:0008360]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp48488_c0_seq1,212,43.3962,0.20142292,3,4,,2.00E-06,Q96MH6,Transmembrane protein 68,Transmembrane protein 68,GO:0016021; GO:0016746,"integral to membrane; transferase activity, transferring acyl groups",PF01553;,,,,,,,,,TMM68_HUMAN,Homo sapiens (Human),metabolic process [GO:0008152] comp48519_c0_seq1,507,49.9014,0.4890277,13,3,,,,,,,,,5.00E-29,CHOYP_LOC585963.1.2,,,,,,,,, comp48557_c0_seq1,1393,41.7085,0.55434811,23561,145683,,2.00E-127,P18238,"ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3)","ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3)",GO:0005471; GO:0009061; GO:0015886; GO:0016021; GO:0005743,ATP:ADP antiporter activity; anaerobic respiration; heme transport; integral to membrane; mitochondrial inner membrane,PF00153;,3.00E-170,CHOYP_LOC100633390.5.5,0,ruditapes_c408,,,,,ADT3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),anaerobic respiration [GO:0009061]; heme transport [GO:0015886]; translation [GO:0006412]; transmembrane transport [GO:0055085] comp48607_c0_seq1,358,48.8827,1.36092565,0,54,,6.00E-19,O97860,Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),GO:0003993; GO:0008199; GO:0008198; GO:0005764,acid phosphatase activity; ferric iron binding; ferrous iron binding; lysosome,PF00149;,,,,,,,,,PPA5_RABIT,Oryctolagus cuniculus (Rabbit), comp48610_c0_seq1,320,37.8125,0.52709874,0,15,,7.00E-08,O75467,Zinc finger protein 324A (Zinc finger protein ZF5128),Zinc finger protein 324A (Zinc finger protein ZF5128),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,Z324A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp48617_c0_seq1,314,42.6752,0.93302382,8,46,,5.00E-27,Q8R3H7,Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2-OST) (2OST) (EC 2.8.2.-),Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2-OST) (2OST) (EC 2.8.2.-),GO:0000139; GO:0004394; GO:0015014; GO:0030202; GO:0016021; GO:0060676,"Golgi membrane; heparan sulfate 2-O-sulfotransferase activity; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin metabolic process; integral to membrane; ureteric bud formation",PF03567;,,,,,,,,,HS2ST_MOUSE,Mus musculus (Mouse),"heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin metabolic process [GO:0030202]; ureteric bud formation [GO:0060676]" comp48638_c0_seq1,1130,44.0708,0.53148538,2500,29578,,1.00E-106,Q6DRC4,Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4),Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4),GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0000166; GO:0006446; GO:0003743; GO:0006413,eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; nucleotide binding; regulation of translational initiation; translation initiation factor activity; translational initiation,PF12353;PF00076;,2.00E-134,CHOYP_EIF3G.1.1,0,ruditapes2_c1673,,,,,EIF3G_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp4864_c0_seq1,223,49.7758,0.4406646,1,1,,8.00E-39,Q9WTI7,Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb),Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb),GO:0005524; GO:0003779; GO:0009925; GO:0005903; GO:0005516; GO:0005829; GO:0070062; GO:0031941; GO:0016328; GO:0051028; GO:0016020; GO:0045121; GO:0003774; GO:0045160; GO:0005643; GO:0005730; GO:0005654; GO:0005543; GO:0038089; GO:0090314; GO:1900748; GO:0006612; GO:2000810; GO:0032420; GO:0060171; GO:0006810,ATP binding; actin binding; basal plasma membrane; brush border; calmodulin binding; cytosol; extracellular vesicular exosome; filamentous actin; lateral plasma membrane; mRNA transport; membrane; membrane raft; motor activity; myosin I complex; nuclear pore; nucleolus; nucleoplasm; phospholipid binding; positive regulation of cell migration by vascular endothelial growth factor signaling pathway; positive regulation of protein targeting to membrane; positive regulation of vascular endothelial growth factor signaling pathway; protein targeting to membrane; regulation of tight junction assembly; stereocilium; stereocilium membrane; transport,PF00612;PF00063;PF06017;,2.00E-41,CHOYP_MYO1C.2.3,3.00E-18,ruditapes_c15733,,,,,MYO1C_MOUSE,Mus musculus (Mouse),membrane organization [GO:0061024]; mRNA transport [GO:0051028]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration by vascular endothelial growth factor signaling pathway [GO:0038089]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein targeting [GO:0006605]; protein targeting to membrane [GO:0006612]; regulation of bicellular tight junction assembly [GO:2000810]; transport [GO:0006810] comp48654_c0_seq1,285,50.1754,0.61905524,2,2,,8.00E-28,Q9WU45,Chloride channel protein 2 (ClC-2),Chloride channel protein 2 (ClC-2),GO:0030554; GO:0060689; GO:0034707; GO:0060041; GO:0005247,adenyl nucleotide binding; cell differentiation involved in salivary gland development; chloride channel complex; retina development in camera-type eye; voltage-gated chloride channel activity,PF00654;,,,,,,,,,CLCN2_CAVPO,Cavia porcellus (Guinea pig), comp48662_c0_seq1,1445,44.7059,0.49086383,105,45,,7.00E-08,A7X413,C-type lectin lectoxin-Lio3 (CTL),C-type lectin lectoxin-Lio3 (CTL),GO:0030246; GO:0005576; GO:0046872,carbohydrate binding; extracellular region; metal ion binding,PF00059;,,,,,,,,,LEC3_LIOPO,Erythrolamprus poecilogyrus (Water snake) (Liophis poecilogyrus), comp48724_c0_seq1,1260,39.9206,1.07880296,6554,28154,,,,,,,,,,,2.00E-99,ruditapes2_c3321,,,,,,, comp48754_c0_seq1,218,40.367,0.93591713,0,20,,7.00E-18,Q8GUQ8,Xanthine dehydrogenase 1 (AtXDH1) (EC 1.17.1.4),Xanthine dehydrogenase 1 (AtXDH1) (EC 1.17.1.4),GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0006145; GO:0000302; GO:0009414; GO:0042554; GO:0004854; GO:0046110,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; purine nucleobase catabolic process; response to reactive oxygen species; response to water deprivation; superoxide anion generation; xanthine dehydrogenase activity; xanthine metabolic process",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH1_ARATH,Arabidopsis thaliana (Mouse-ear cress),purine nucleobase catabolic process [GO:0006145]; response to reactive oxygen species [GO:0000302]; response to water deprivation [GO:0009414]; superoxide anion generation [GO:0042554]; xanthine metabolic process [GO:0046110] comp48788_c0_seq1,432,37.963,0.19741747,9,33,,1.00E-07,Q13163,Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5),Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5),GO:0005524; GO:0070375; GO:0000187; GO:0071499; GO:0005829; GO:0007507; GO:0046872; GO:0032088; GO:0043066; GO:0090051; GO:2000342; GO:0043154; GO:2001240; GO:0034115; GO:0045415; GO:0060761; GO:0000122; GO:0048011; GO:0005634; GO:0018108; GO:0030307; GO:0050679; GO:0045944; GO:0004672; GO:0004674; GO:0004713; GO:0005819,ATP binding; ERK5 cascade; activation of MAPK activity; cellular response to laminar fluid shear stress; cytosol; heart development; metal ion binding; negative regulation of NF-kappaB transcription factor activity; negative regulation of apoptotic process; negative regulation of cell migration involved in sprouting angiogenesis; negative regulation of chemokine (C-X-C motif) ligand 2 production; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of heterotypic cell-cell adhesion; negative regulation of interleukin-8 biosynthetic process; negative regulation of response to cytokine stimulus; negative regulation of transcription from RNA polymerase II promoter; neurotrophin TRK receptor signaling pathway; nucleus; peptidyl-tyrosine phosphorylation; positive regulation of cell growth; positive regulation of epithelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; spindle,PF00564;PF00069;,,,,,,,,,MP2K5_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165] comp48791_c0_seq1,1435,35.8188,0.86043552,102,56,,3.00E-28,Q5R5D2,Sclerostin domain-containing protein 1,Sclerostin domain-containing protein 1,GO:0016055; GO:0005615; GO:0031069; GO:0060648; GO:0030514; GO:0090090; GO:0010454; GO:0042475; GO:0007389,Wnt receptor signaling pathway; extracellular space; hair follicle morphogenesis; mammary gland bud morphogenesis; negative regulation of BMP signaling pathway; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cell fate commitment; odontogenesis of dentin-containing tooth; pattern specification process,PF05463;,,,,,,,,,SOSD1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),hair follicle morphogenesis [GO:0031069]; mammary gland bud morphogenesis [GO:0060648]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell fate commitment [GO:0010454]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; Wnt signaling pathway [GO:0016055] comp48811_c0_seq1,225,42.2222,0.50089642,1,9,,1.00E-06,P49021,Protein timeless,Protein timeless,GO:0071482; GO:0060086; GO:0007620; GO:0005737; GO:0008062; GO:0009649; GO:0045475; GO:0007617; GO:0046957; GO:0000122; GO:2000678; GO:0005634; GO:0048471; GO:0009648; GO:0043234; GO:0046982; GO:0006606; GO:0045187; GO:0042306; GO:0030431,"cellular response to light stimulus; circadian temperature homeostasis; copulation; cytoplasm; eclosion rhythm; entrainment of circadian clock; locomotor rhythm; mating behavior; negative phototaxis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription regulatory region DNA binding; nucleus; perinuclear region of cytoplasm; photoperiodism; protein complex; protein heterodimerization activity; protein import into nucleus; regulation of circadian sleep/wake cycle, sleep; regulation of protein import into nucleus; sleep",PF04821;,,,,,,,,,TIM_DROME,Drosophila melanogaster (Fruit fly),"cellular response to light stimulus [GO:0071482]; circadian behavior [GO:0048512]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; circadian temperature homeostasis [GO:0060086]; copulation [GO:0007620]; eclosion rhythm [GO:0008062]; entrainment of circadian clock [GO:0009649]; locomotor rhythm [GO:0045475]; mating behavior [GO:0007617]; negative phototaxis [GO:0046957]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; photoperiodism [GO:0009648]; positive regulation of phagocytosis [GO:0050766]; protein import into nucleus [GO:0006606]; regulation of circadian sleep/wake cycle [GO:0042749]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of phagocytosis [GO:0050764]; regulation of protein import into nucleus [GO:0042306]; rhythmic behavior [GO:0007622]; sleep [GO:0030431]" comp48818_c0_seq1,443,43.7923,0.37755294,10,4,,3.00E-77,Q07243,Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1),Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1),GO:0000979; GO:0046872; GO:0005634; GO:0045944; GO:0046686; GO:0006979; GO:0003700; GO:0006351,"RNA polymerase II core promoter sequence-specific DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to cadmium ion; response to oxidative stress; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,1.00E-60,CHOYP_LOC100693092.1.1,,,,,,,MTF1_MOUSE,Mus musculus (Mouse),"positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]" comp48819_c0_seq1,964,39.834,0.55920477,392,2232,,6.00E-39,Q9NP64,Nucleolar protein of 40 kDa (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein) (Zinc finger CCHC domain-containing protein 17),Nucleolar protein of 40 kDa (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein) (Zinc finger CCHC domain-containing protein 17),GO:0003723; GO:0022625; GO:0005730; GO:0008270,RNA binding; cytosolic large ribosomal subunit; nucleolus; zinc ion binding,PF00575;,,,,,,,,,NO40_HUMAN,Homo sapiens (Human),mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp48834_c0_seq1,461,42.0824,0.25000118,4,38,,1.00E-25,Q64612,Receptor-type tyrosine-protein phosphatase V (R-PTP-V) (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase) (Osteotesticular protein-tyrosine phosphatase) (OST-PTP),Receptor-type tyrosine-protein phosphatase V (R-PTP-V) (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase) (Osteotesticular protein-tyrosine phosphatase) (OST-PTP),GO:0046849; GO:0016021; GO:0035335; GO:0004725,bone remodeling; integral to membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00041;PF00102;,7.00E-46,CHOYP_LOC100909333.1.1,,,,,,,PTPRV_RAT,Rattus norvegicus (Rat),bone remodeling [GO:0046849] comp48842_c0_seq1,713,36.7461,0.33521193,6,110,,4.00E-12,Q99PV8,B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (mRit1),B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (mRit1),GO:0000978; GO:0001077; GO:0033077; GO:0033153; GO:0046632; GO:0003382; GO:0003334; GO:0046872; GO:0043066; GO:0008285; GO:0005634; GO:0042475; GO:0071678; GO:0043368; GO:0031077; GO:0010837; GO:0019216; GO:0045664; GO:0021773; GO:0048538,RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; T cell differentiation in thymus; T cell receptor V(D)J recombination; alpha-beta T cell differentiation; epithelial cell morphogenesis; keratinocyte development; metal ion binding; negative regulation of apoptotic process; negative regulation of cell proliferation; nucleus; odontogenesis of dentin-containing tooth; olfactory bulb axon guidance; positive T cell selection; post-embryonic camera-type eye development; regulation of keratinocyte proliferation; regulation of lipid metabolic process; regulation of neuron differentiation; striatal medium spiny neuron differentiation; thymus development,PF00096;,,,,,,,,,BC11B_MOUSE,Mus musculus (Mouse),alpha-beta T cell differentiation [GO:0046632]; axonogenesis [GO:0007409]; central nervous system neuron differentiation [GO:0021953]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; odontogenesis of dentin-containing tooth [GO:0042475]; olfactory bulb axon guidance [GO:0071678]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive T cell selection [GO:0043368]; post-embryonic camera-type eye development [GO:0031077]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of keratinocyte proliferation [GO:0010837]; regulation of lipid metabolic process [GO:0019216]; regulation of neuron differentiation [GO:0045664]; signal transduction [GO:0007165]; skin development [GO:0043588]; striatal medium spiny neuron differentiation [GO:0021773]; T cell differentiation in thymus [GO:0033077]; T cell receptor V(D)J recombination [GO:0033153]; thymus development [GO:0048538] comp48981_c0_seq1,1765,33.0878,1.05991208,2717,68,,,,,,,,,6.00E-22,CHOYP_LOC100185271.1.1,4.00E-34,ruditapes_c7463,,,,,,, comp48985_c0_seq1,491,48.0652,0.86014343,11,0,,3.00E-34,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,1.00E-12,CHOYP_LOC100374755.3.3,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp49053_c0_seq1,306,43.1373,0.42768044,3,30,,6.00E-16,Q9V3Z6,Myosin-VIIa (DmVIIa) (Protein crinkled),Myosin-VIIa (DmVIIa) (Protein crinkled),GO:0005524; GO:0003779; GO:0007015; GO:0030048; GO:0030898; GO:0048800; GO:0045179; GO:0008407; GO:0035293; GO:0035317; GO:0008586; GO:0005902; GO:0003774; GO:0031477; GO:0007605,ATP binding; actin binding; actin filament organization; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; apical cortex; chaeta morphogenesis; chitin-based larval cuticle pattern formation; imaginal disc-derived wing hair organization; imaginal disc-derived wing vein morphogenesis; microvillus; motor activity; myosin VII complex; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_DROME,Drosophila melanogaster (Fruit fly),actin filament-based movement [GO:0030048]; actin filament organization [GO:0007015]; antennal development [GO:0007469]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; chitin-based larval cuticle pattern formation [GO:0035293]; follicle cell microvillus organization [GO:0032529]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605] comp49060_c0_seq1,501,42.7146,0.55917794,18,9,,3.00E-43,Q7ZU90,Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12),GO:0005524; GO:0016887; GO:0003677; GO:0006281; GO:0006338; GO:0004386; GO:0000166; GO:0005634; GO:0006974,ATP binding; ATPase activity; DNA binding; DNA repair; chromatin remodeling; helicase activity; nucleotide binding; nucleus; response to DNA damage stimulus,PF00271;PF16759;PF00176;,,,,,,,,,CHD1L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] comp49065_c0_seq1,1172,36.6041,0.3339102,505,7686,,1.00E-129,Q8UVY2,Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) (Bx24),Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) (Bx24),GO:0005730; GO:0042254,nucleolus; ribosome biogenesis,PF04427;,9.00E-132,CHOYP_BRX1.1.1,5.00E-152,ruditapes_c7544,,,,,BRX1_XENLA,Xenopus laevis (African clawed frog),ribosome biogenesis [GO:0042254] comp49096_c0_seq1,456,49.3421,0.47210971,4,18,,5.00E-27,Q9JLI3,"Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]","Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]",GO:0005794; GO:0005783; GO:0005615; GO:0016021; GO:0004222; GO:0006508; GO:0008270,Golgi apparatus; endoplasmic reticulum; extracellular space; integral to membrane; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01431;PF05649;,,,,,,,,,MMEL1_MOUSE,Mus musculus (Mouse), comp49102_c0_seq1,453,40.6181,0.5066989,14,40,,8.00E-31,Q66HY7,Eukaryotic translation initiation factor 4E type 3 (eIF-4E type 3) (eIF-4E3) (eIF4E type 3) (eIF4E-3),Eukaryotic translation initiation factor 4E type 3 (eIF-4E type 3) (eIF-4E3) (eIF4E type 3) (eIF4E-3),GO:0005737; GO:0005845; GO:0006417; GO:0003743,cytoplasm; mRNA cap binding complex; regulation of translation; translation initiation factor activity,PF01652;,,,,,,,,,IF4E3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of translation [GO:0006417] comp49170_c0_seq1,277,47.6534,0.33902881,2,17,,3.00E-19,Q8WZA2,Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII),Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII),GO:0007186; GO:0017016; GO:0005088; GO:0030552; GO:0005952; GO:0008603; GO:0019933; GO:0017156; GO:0005829; GO:0006112; GO:0030073; GO:0005886; GO:0030168; GO:0017157; GO:0050796; GO:0051056; GO:0007264; GO:0044281,G-protein coupled receptor signaling pathway; Ras GTPase binding; Ras guanyl-nucleotide exchange factor activity; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; cAMP-mediated signaling; calcium ion-dependent exocytosis; cytosol; energy reserve metabolic process; insulin secretion; plasma membrane; platelet activation; regulation of exocytosis; regulation of insulin secretion; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; small molecule metabolic process,PF00027;PF00610;PF00617;PF00618;,1.00E-32,CHOYP_LOC100373735.1.1,,,,,,,RPGF4_HUMAN,Homo sapiens (Human),calcium ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; regulation of exocytosis [GO:0017157]; regulation of insulin secretion [GO:0050796]; small GTPase mediated signal transduction [GO:0007264] comp49170_c0_seq2,224,47.3214,0.41529067,0,17,,5.00E-07,O95398,Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI),Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI),GO:0017034; GO:0032486; GO:0001525; GO:0030552; GO:0005952; GO:0008603; GO:0019933; GO:0008283; GO:0071320; GO:0012505; GO:0006112; GO:0061028; GO:0005886; GO:0030168; GO:0032854; GO:0045766; GO:0030822; GO:0051496; GO:2000249; GO:0050796; GO:0044281,Rap guanyl-nucleotide exchange factor activity; Rap protein signal transduction; angiogenesis; cAMP binding; cAMP-dependent protein kinase complex; cAMP-dependent protein kinase regulator activity; cAMP-mediated signaling; cell proliferation; cellular response to cAMP; endomembrane system; energy reserve metabolic process; establishment of endothelial barrier; plasma membrane; platelet activation; positive regulation of Rap GTPase activity; positive regulation of angiogenesis; positive regulation of cAMP catabolic process; positive regulation of stress fiber assembly; regulation of actin cytoskeleton reorganization; regulation of insulin secretion; small molecule metabolic process,PF00027;PF00610;PF00617;PF00618;,,,,,,,,,RPGF3_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; artery development [GO:0060840]; brain development [GO:0007420]; cAMP-mediated signaling [GO:0019933]; cell proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to L-dopa [GO:1904474]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dorsal root ganglion development [GO:1990791]; establishment of endothelial barrier [GO:0061028]; liver regeneration [GO:0097421]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of syncytium formation by plasma membrane fusion [GO:0034242]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcium ion transmembrane transport [GO:1904427]; positive regulation of cAMP catabolic process [GO:0030822]; positive regulation of cell size [GO:0045793]; positive regulation of GTPase activity [GO:0043547]; positive regulation of GTP binding [GO:1904426]; positive regulation of hydrogen:potassium-exchanging ATPase activity [GO:1904453]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; Rap protein signal transduction [GO:0032486]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of insulin secretion [GO:0050796]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; spinal cord development [GO:0021510] comp49192_c0_seq1,290,40,0.26075579,4,5,,4.00E-13,Q9UJ41,Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5),Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5),GO:0003677; GO:0017112; GO:0005769; GO:0006897; GO:0015031; GO:0055037; GO:0008270,DNA binding; Rab guanyl-nucleotide exchange factor activity; early endosome; endocytosis; protein transport; recycling endosome; zinc ion binding,PF02204;PF01754;,5.00E-20,CHOYP_RABX5.1.2,,,,,,,RABX5_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein targeting to membrane [GO:0006612]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] comp49199_c0_seq1,838,38.4248,0.52128064,23,94,,4.00E-07,Q8K2R5,Zinc finger protein 668,Zinc finger protein 668,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN668_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp49220_c0_seq1,277,31.769,0.3102719,3,5,,5.00E-22,P52963,Band 4.1-like protein 4A (Protein NBL4),Band 4.1-like protein 4A (Protein NBL4),GO:0005737; GO:0005856; GO:0019898,cytoplasm; cytoskeleton; extrinsic to membrane,PF08736;PF09380;PF00373;PF09379;,6.00E-44,CHOYP_LOC100163621.2.2,,,,,,,E41LA_MOUSE,Mus musculus (Mouse), comp49226_c0_seq1,707,38.1895,0.70311865,547,3688,,3.00E-25,Q9Y3D5,"28S ribosomal protein S18c, mitochondrial (MRP-S18-c) (Mrps18-c) (S18mt-c) (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1)","28S ribosomal protein S18c, mitochondrial (MRP-S18-c) (Mrps18-c) (S18mt-c) (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1)",GO:0005763; GO:0003735; GO:0006412,mitochondrial small ribosomal subunit; structural constituent of ribosome; translation,PF01084;,,,6.00E-28,ruditapes_c429,,,,,RT18C_HUMAN,Homo sapiens (Human),mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412] comp49242_c0_seq1,381,44.357,1.02623969,518,1252,,2.00E-21,P26686,Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed),Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed),GO:0071013; GO:0003729; GO:0006376; GO:0007067; GO:0016607; GO:0000166; GO:0005700; GO:0071011; GO:0000381; GO:0035327,"catalytic step 2 spliceosome; mRNA binding; mRNA splice site selection; mitosis; nuclear speck; nucleotide binding; polytene chromosome; precatalytic spliceosome; regulation of alternative mRNA splicing, via spliceosome; transcriptionally active chromatin",PF00076;,2.00E-33,CHOYP_SRSF4.5.6,,,,,,,SRR55_DROME,Drosophila melanogaster (Fruit fly),"mitotic nuclear division [GO:0007067]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]" comp49249_c0_seq1,708,42.7966,1.0925964,431,3383,,3.00E-62,Q26551,Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin),Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin),GO:0005788; GO:0042277; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum lumen; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,3.00E-15,CHOYP_PPID.1.1,2.00E-22,ruditapes_c4268,,,,,PPIB_SCHMA,Schistosoma mansoni (Blood fluke),protein folding [GO:0006457] comp49306_c0_seq1,362,57.4586,1.27829722,0,22,,8.00E-74,Q6A780,Error-prone DNA polymerase (EC 2.7.7.7),Error-prone DNA polymerase (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0006281; GO:0006260; GO:0003887; GO:0005737,3'-5' exonuclease activity; DNA binding; DNA repair; DNA replication; DNA-directed DNA polymerase activity; cytoplasm,PF07733;PF14579;PF02811;PF01336;,,,,,,,,,DNAE2_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA repair [GO:0006281]; DNA replication [GO:0006260] comp49343_c0_seq1,466,43.5622,0.45463605,16,54,,4.00E-06,Q2EI20,RE1-silencing transcription factor (Neural-restrictive silencer factor),RE1-silencing transcription factor (Neural-restrictive silencer factor),GO:0021785; GO:0021610; GO:0046872; GO:0010629; GO:0045879; GO:0001764; GO:0003676; GO:0005634; GO:0043065; GO:0000981; GO:0060831,branchiomotor neuron axon guidance; facial nerve morphogenesis; metal ion binding; negative regulation of gene expression; negative regulation of smoothened signaling pathway; neuron migration; nucleic acid binding; nucleus; positive regulation of apoptotic process; sequence-specific DNA binding RNA polymerase II transcription factor activity; smoothened signaling pathway involved in dorsal/ventral neural tube patterning,,,,,,,,,,REST_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"branchiomotor neuron axon guidance [GO:0021785]; facial nerve morphogenesis [GO:0021610]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron migration [GO:0001764]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; transcription, DNA-templated [GO:0006351]" comp49358_c0_seq1,439,57.631,0.85464103,0,76,,1.00E-20,P41203,Elongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu),Elongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF03144;PF03143;,,,,,,,,,EF1A_DESMO,Desulfurococcus mobilis, comp49381_c0_seq1,206,38.835,0.91479428,6,4,,4.00E-06,E1PL40,O-acetyl-ADP-ribose deacetylase 2 (EC 3.5.1.-) (Regulator of RNase III activity 2),O-acetyl-ADP-ribose deacetylase 2 (EC 3.5.1.-) (Regulator of RNase III activity 2),GO:0019213; GO:0060701; GO:0001883; GO:0042278; GO:0008428,deacetylase activity; negative regulation of ribonuclease activity; purine nucleoside binding; purine nucleoside metabolic process; ribonuclease inhibitor activity,PF01661;,,,,,,,,,YMDB2_PANVC,Pantoea vagans (strain C9-1) (Pantoea agglomerans (strain C9-1)),negative regulation of ribonuclease activity [GO:0060701]; purine nucleoside metabolic process [GO:0042278] comp49385_c0_seq1,638,43.1034,0.71052806,25,72,,2.00E-12,Q80X66,BTB/POZ domain-containing protein 10,BTB/POZ domain-containing protein 10 (Glucose metabolism-related protein 1),GO:0005634,nucleus,,9.00E-15,CHOYP_LOC657718.1.1,,,,,,,BTBDA_MOUSE,Mus musculus (Mouse),negative regulation of neuron death [GO:1901215]; positive regulation of phosphorylation [GO:0042327] comp49388_c0_seq1,667,42.2789,0.88648627,409,639,,,,,,,,,0,CHOYP_COX1.5.15,2.00E-20,ruditapes_c16723,,,,,,, comp49395_c0_seq1,685,45.2555,1.00004378,30,0,,1.00E-16,P13908,Neuronal acetylcholine receptor subunit non-alpha-2 (GFN-alpha-2),Neuronal acetylcholine receptor subunit non-alpha-2 (GFN-alpha-2),GO:0004889; GO:0030054; GO:0016021; GO:0045211,acetylcholine-activated cation-selective channel activity; cell junction; integral to membrane; postsynaptic membrane,PF02931;PF02932;,,,,,,,,,ACHN2_CARAU,Carassius auratus (Goldfish), comp49405_c0_seq1,2026,41.1155,0.55052252,56,263,,4.00E-48,Q05481,Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10),Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10),GO:0003677; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZNF91_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transposon integration [GO:0070895]; transcription, DNA-templated [GO:0006351]" comp49411_c0_seq1,647,42.6584,1.32815117,97,38,,6.00E-26,Q90XN9,Homeobox protein HMX3-B (Homeobox protein H6 family member 3-B) (Homeobox protein Nkx-5.1.2) (OlNkx-5.1.2),Homeobox protein HMX3-B (Homeobox protein H6 family member 3-B) (Homeobox protein Nkx-5.1.2) (OlNkx-5.1.2),GO:0030154; GO:0007399; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"cell differentiation; nervous system development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;,1.00E-26,CHOYP_HMX1.1.1,,,,,,,HMX3B_ORYLA,Oryzias latipes (Japanese rice fish) (Japanese killifish),"cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp49454_c0_seq1,223,37.2197,1.46669616,5,38,,,,,,,,,,,8.00E-14,ruditapes_c25199,,,,,,, comp49455_c0_seq1,531,43.8795,0.55740356,2,86,,2.00E-43,Q9CXR1,Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4),Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4),GO:0016491,oxidoreductase activity,PF00106;,,,,,,,,,DHRS7_MOUSE,Mus musculus (Mouse), comp49482_c0_seq1,423,40.1891,0.88468988,156,2066,,1.00E-32,P50238,Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP),Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP),GO:0003680; GO:0008301; GO:0008283; GO:0071493; GO:0071236; GO:0005737; GO:0007507; GO:0006955; GO:0008630; GO:0042277; GO:0060741; GO:0010468; GO:0010033; GO:0010043; GO:0008270,"AT DNA binding; DNA binding, bending; cell proliferation; cellular response to UV-B; cellular response to antibiotic; cytoplasm; heart development; immune response; intrinsic apoptotic signaling pathway in response to DNA damage; peptide binding; prostate gland stromal morphogenesis; regulation of gene expression; response to organic substance; response to zinc ion; zinc ion binding",PF00412;,,,2.00E-51,ruditapes_lrc38487,,,,,CRIP1_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; cellular response to antibiotic [GO:0071236]; cellular response to UV-B [GO:0071493]; heart development [GO:0007507]; immune response [GO:0006955]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; prostate gland stromal morphogenesis [GO:0060741]; regulation of gene expression [GO:0010468]; response to organic substance [GO:0010033]; response to zinc ion [GO:0010043] comp49500_c0_seq1,477,38.1551,0.59810073,8,85,,3.00E-33,Q9NYQ7,Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_HUMAN,Homo sapiens (Human),"axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp49524_c0_seq1,232,46.9828,0.39980153,3,0,,2.00E-11,P97459,Neuronal PAS domain-containing protein 1 (Neuronal PAS1),Neuronal PAS domain-containing protein 1 (Neuronal PAS1),GO:0003677; GO:0042711; GO:0000122; GO:0005634; GO:0004871; GO:0001964; GO:0006351,"DNA binding; maternal behavior; negative regulation of transcription from RNA polymerase II promoter; nucleus; signal transducer activity; startle response; transcription, DNA-dependent",PF00010;PF00989;PF08447;,1.00E-19,CHOYP_TRH.1.1,,,,,,,NPAS1_MOUSE,Mus musculus (Mouse),"developmental process [GO:0032502]; maternal behavior [GO:0042711]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; startle response [GO:0001964]; transcription, DNA-templated [GO:0006351]" comp49578_c0_seq2,359,38.1616,0.46154204,10,51,,2.00E-55,Q32L63,Vacuolar protein sorting-associated protein VTA1 homolog,Vacuolar protein sorting-associated protein VTA1 homolog,GO:0010008; GO:0015031,endosome membrane; protein transport,,1.00E-34,CHOYP_VTA1.1.1,,,,,,,VTA1_BOVIN,Bos taurus (Bovine),protein transport [GO:0015031] comp49588_c0_seq1,574,42.1603,1.23399475,35,44,,2.00E-08,A6NEN9,Uncharacterized protein CXorf65,Uncharacterized protein CXorf65,,,,,,1.00E-41,ruditapes_c14604,,,,,CX065_HUMAN,Homo sapiens (Human), comp49600_c0_seq1,563,44.9378,0.42406149,11,63,,6.00E-10,Q9FJX6,Formin-like protein 6 (AtFH6) (AtFORMIN-6),Formin-like protein 6 (AtFH6) (AtFORMIN-6),GO:0003779; GO:0005884; GO:0045010; GO:0005618; GO:0016021; GO:0005730; GO:0009524; GO:0005886; GO:0005819,actin binding; actin filament; actin nucleation; cell wall; integral to membrane; nucleolus; phragmoplast; plasma membrane; spindle,PF02181;,2.00E-15,CHOYP_INF2.3.5,,,,,,,FH6_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp49600_c1_seq1,559,43.8283,0.37848188,10,76,,8.00E-18,Q9C0D6,FH2 domain-containing protein 1,FH2 domain-containing protein 1,,,PF02181;,,,,,,,,,FHDC1_HUMAN,Homo sapiens (Human), comp49643_c0_seq1,390,33.3333,0.38818821,431,863,,2.00E-25,P0CM86,Cytochrome c oxidase assembly protein COX19,Cytochrome c oxidase assembly protein COX19,GO:0005758,mitochondrial intermembrane space,PF06747;,,,,,,,,,COX19_CRYNJ,Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans),aerobic respiration [GO:0009060]; mitochondrial respiratory chain complex IV assembly [GO:0033617] comp49647_c0_seq1,267,62.9213,1.35707922,3,1,,2.00E-06,P0CF99,GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.57) (Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase) (Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase) (Phosphatidylinositol alpha-mannosyltransferase) (PI alpha-mannosyltransferase),GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.57) (Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase) (Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase) (Phosphatidylinositol alpha-mannosyltransferase) (PI alpha-mannosyltransferase),GO:0046474; GO:0033164; GO:0009247; GO:0047264; GO:0016020; GO:0009405; GO:0043750; GO:0046488,glycerophospholipid biosynthetic process; glycolipid 6-alpha-mannosyltransferase activity; glycolipid biosynthetic process; heteroglycan alpha-mannosyltransferase activity; membrane; pathogenesis; phosphatidylinositol alpha-mannosyltransferase activity; phosphatidylinositol metabolic process,PF13579;PF00534;,,,,,,,,,PIMC_MYCTU,Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh),glycerophospholipid biosynthetic process [GO:0046474]; glycolipid biosynthetic process [GO:0009247]; pathogenesis [GO:0009405]; phosphatidylinositol metabolic process [GO:0046488] comp49671_c0_seq1,373,38.874,1.71429804,7,0,,,,,,,,,4.00E-23,CHOYP_contig_046226,4.00E-26,ruditapes2_c1704,,,,,,, comp4973_c0_seq1,306,45.098,0.96744731,0,0,,3.00E-08,Q99N01,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0005886; GO:0042403; GO:0015349,integral to membrane; plasma membrane; thyroid hormone metabolic process; thyroid hormone transmembrane transporter activity,PF07648;PF03137;,,,,,,,,,SO4A1_RAT,Rattus norvegicus (Rat),sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] comp4973_c0_seq2,343,46.3557,1.03418601,0,4,,4.00E-10,Q96BD0,Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0005886; GO:0043252; GO:0055085; GO:0005215,integral to membrane; plasma membrane; sodium-independent organic anion transport; transmembrane transport; transporter activity,PF07648;PF03137;,,,,,,,,,SO4A1_HUMAN,Homo sapiens (Human),sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp49761_c0_seq2,503,31.8091,0,1,13,,2.00E-06,Q79FL2,Uncharacterized PPE family protein PPE24,,GO:0040007,growth,,,,,,,,,,PPE24_MYCTU,, comp49792_c0_seq1,433,45.9584,0.44088004,9,47,,1.00E-18,Q5ZIJ9,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB2_CHICK,Gallus gallus (Chicken),Notch signaling pathway [GO:0007219] comp49809_c0_seq2,378,44.4444,0.53721141,2,38,,9.00E-59,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,5.00E-85,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp49820_c0_seq1,768,38.9323,0.53284458,648,6920,,4.00E-36,Q5ZJ39,Density-regulated protein (DRP),Density-regulated protein (DRP),GO:0003743,translation initiation factor activity,PF01253;,9.00E-60,CHOYP_PHUM_PHUM319040.1.1,3.00E-70,ruditapes_c8658,,,,,DENR_CHICK,Gallus gallus (Chicken),formation of translation preinitiation complex [GO:0001731]; IRES-dependent translational initiation [GO:0002192]; ribosome disassembly [GO:0032790] comp49873_c0_seq1,1680,36.7262,0.5251995,290,3709,,2.00E-74,Q9NQT5,Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10),Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10),GO:0000175; GO:0071034; GO:0045006; GO:0003723; GO:0000177; GO:0005829; GO:0043928; GO:0045190; GO:0000176; GO:0005730; GO:0045830; GO:0006364; GO:0035327,3'-5'-exoribonuclease activity; CUT catabolic process; DNA deamination; RNA binding; cytoplasmic exosome (RNase complex); cytosol; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; isotype switching; nuclear exosome (RNase complex); nucleolus; positive regulation of isotype switching; rRNA processing; transcriptionally active chromatin,PF15985;,8.00E-46,CHOYP_EXOS3.1.1,,,,,,,EXOS3_HUMAN,Homo sapiens (Human),"CUT catabolic process [GO:0071034]; DNA deamination [GO:0045006]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; isotype switching [GO:0045190]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of isotype switching [GO:0045830]; regulation of mRNA stability [GO:0043488]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475]" comp49884_c0_seq2,553,43.3996,0.51921444,2,0,,1.00E-10,A7MCS3,UPF0764 protein C16orf89 homolog,UPF0764 protein C16orf89 homolog,GO:0005576,extracellular region,PF15882;,,,,,,,,,CP089_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp49971_c0_seq2,202,36.6337,0.8903727,0,5,,4.00E-14,P47736,Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1),Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1),GO:0005096; GO:0003924; GO:0000139; GO:0005829; GO:0016020; GO:0032318; GO:0007165,GTPase activator activity; GTPase activity; Golgi membrane; cytosol; membrane; regulation of Ras GTPase activity; signal transduction,PF02188;PF02145;,,,,,,,,,RPGP1_HUMAN,Homo sapiens (Human),cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp49982_c0_seq1,525,49.9048,0.61359219,14,2,,8.00E-74,Q9Z2V5,Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2),Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2),GO:0070846; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0016235; GO:0070842; GO:0048487; GO:0005901; GO:0031252; GO:0070301; GO:0071218; GO:0005881; GO:0005829; GO:0030286; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0032418; GO:0016236; GO:0008017; GO:0006515; GO:0007026; GO:0045861; GO:0005634; GO:0034983; GO:0048471; GO:0070845; GO:0090035; GO:0010634; GO:1901300; GO:0010870; GO:0009967; GO:0043241; GO:0000209; GO:0070201; GO:0010469; GO:0006355; GO:0070848; GO:0009636; GO:0006351; GO:0042903; GO:0043130; GO:0043162; GO:0008270,"Hsp90 deacetylation; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); aggresome; aggresome assembly; beta-tubulin binding; caveola; cell leading edge; cellular response to hydrogen peroxide; cellular response to misfolded protein; cytoplasmic microtubule; cytosol; dynein complex; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; lysosome localization; macroautophagy; microtubule binding; misfolded or incompletely synthesized protein catabolic process; negative regulation of microtubule depolymerization; negative regulation of proteolysis; nucleus; peptidyl-lysine deacetylation; perinuclear region of cytoplasm; polyubiquitinated misfolded protein transport; positive regulation of chaperone-mediated protein complex assembly; positive regulation of epithelial cell migration; positive regulation of hydrogen peroxide-mediated programmed cell death; positive regulation of receptor biosynthetic process; positive regulation of signal transduction; protein complex disassembly; protein polyubiquitination; regulation of establishment of protein localization; regulation of receptor activity; regulation of transcription, DNA-dependent; response to growth factor stimulus; response to toxic substance; transcription, DNA-dependent; tubulin deacetylase activity; ubiquitin binding; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; zinc ion binding",PF00850;PF02148;,2.00E-54,CHOYP_LOC100877749.1.1,,,,,,,HDAC6_MOUSE,Mus musculus (Mouse),"aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]" comp50003_c0_seq1,241,35.6846,1.08461251,5,3,,6.00E-12,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp50027_c0_seq1,297,47.138,1.09829255,8,0,,5.00E-09,Q28008,C-type lectin domain family 3 member A (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin),C-type lectin domain family 3 member A (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin),GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,CLC3A_BOVIN,Bos taurus (Bovine), comp5002_c0_seq1,203,42.3645,0.82640894,0,1,,1.00E-21,O75503,Ceroid-lipofuscinosis neuronal protein 5 (Protein CLN5),Ceroid-lipofuscinosis neuronal protein 5 (Protein CLN5),GO:0005794; GO:0007420; GO:0008219; GO:0005783; GO:0070085; GO:0016021; GO:0007042; GO:0005765; GO:0005537; GO:0042551; GO:0048471; GO:0030163; GO:0006465; GO:0005775; GO:0007601,Golgi apparatus; brain development; cell death; endoplasmic reticulum; glycosylation; integral to membrane; lysosomal lumen acidification; lysosomal membrane; mannose binding; neuron maturation; perinuclear region of cytoplasm; protein catabolic process; signal peptide processing; vacuolar lumen; visual perception,PF15014;,9.00E-15,CHOYP_BRAFLDRAFT_220284.1.1,,,,,,,CLN5_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; glycosylation [GO:0070085]; lysosomal lumen acidification [GO:0007042]; neurogenesis [GO:0022008]; neuron maturation [GO:0042551]; protein catabolic process [GO:0030163]; signal peptide processing [GO:0006465] comp50078_c0_seq1,367,45.5041,0.87463513,10,4,,1.00E-29,P59894,Doublecortin domain-containing protein 1,Doublecortin domain-containing protein 1,GO:0035556,intracellular signal transduction,,,,,,,,,,DCDC1_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556] comp50109_c0_seq1,618,37.055,0.61474569,5,51,,3.00E-09,Q2XWK0,Synaptic vesicle 2-related protein (SV2-related protein),Synaptic vesicle 2-related protein (SV2-related protein),GO:0030054; GO:0016021; GO:0030672; GO:0022857,cell junction; integral to membrane; synaptic vesicle membrane; transmembrane transporter activity,PF07690;PF00083;,1.00E-50,CHOYP_SVOP.1.2,,,,,,,SVOP_XENLA,Xenopus laevis (African clawed frog), comp50186_c0_seq2,393,43.5115,0.43154715,8,0,,3.00E-61,Q95LL3,TBC1 domain family member 22B,TBC1 domain family member 22B,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,2.00E-52,CHOYP_TBC1D22A.1.1,,,,,,,TB22B_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp50191_c0_seq1,210,45.7143,0.46785983,5,0,,1.00E-24,P30825,High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter),High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter),GO:0006865; GO:0015181; GO:0005887; GO:0055085,amino acid transport; arginine transmembrane transporter activity; integral to plasma membrane; transmembrane transport,PF13520;PF13906;,6.00E-30,CHOYP_CTR2.1.1,,,,,,,CTR1_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; L-ornithine transmembrane transport [GO:1903352]; transport [GO:0006810] comp50226_c0_seq1,420,57.1429,0.90859607,0,35,,5.00E-39,O28058,Uncharacterized protein AF_2225,Uncharacterized protein AF_2225,GO:0003824; GO:0046872,catalytic activity; metal ion binding,PF01557;,,,,,,,,,Y2225_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126),metabolic process [GO:0008152] comp50253_c0_seq1,541,46.0259,1.31158067,13,972,,6.00E-38,P15090,"Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein) (ALBP) (Adipocyte-type fatty acid-binding protein) (A-FABP) (AFABP) (Fatty acid-binding protein 4)","Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein) (ALBP) (Adipocyte-type fatty acid-binding protein) (A-FABP) (AFABP) (Fatty acid-binding protein 4)",GO:0050873; GO:0071285; GO:0042632; GO:0001816; GO:0005504; GO:0005811; GO:0006469; GO:0045892; GO:0005634; GO:0050729; GO:0044281; GO:0005215; GO:0019433; GO:0050872,"brown fat cell differentiation; cellular response to lithium ion; cholesterol homeostasis; cytokine production; fatty acid binding; lipid particle; negative regulation of protein kinase activity; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of inflammatory response; small molecule metabolic process; transporter activity; triglyceride catabolic process; white fat cell differentiation",PF00061;,,,1.00E-47,ruditapes_c11269,,,,,FABP4_HUMAN,Homo sapiens (Human),"brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of inflammatory response [GO:0050729]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]" comp50260_c0_seq1,202,45.0495,0.49035018,5,41,,2.00E-07,P42858,Huntingtin (Huntington disease protein) (HD protein),Huntingtin (Huntington disease protein) (HD protein),GO:0006888; GO:0005794; GO:0007030; GO:0051938; GO:0009952; GO:0005776; GO:0030424; GO:0008088; GO:0048487; GO:0007569; GO:0000052; GO:0030659; GO:0005829; GO:0030425; GO:0008340; GO:0050809; GO:0007212; GO:0045505; GO:0005783; GO:0007029; GO:0016197; GO:0000132; GO:0042445; GO:0016234; GO:0030073; GO:0055072; GO:0019244; GO:0005770; GO:0007626; GO:2001237; GO:0043524; GO:0021990; GO:0051402; GO:0048666; GO:0005634; GO:0021988; GO:0048513; GO:0048341; GO:0043234; GO:0006606; GO:0019805; GO:0046902; GO:0051881; GO:0046825; GO:0034047; GO:0048167; GO:0051592; GO:0006890; GO:0035176; GO:0007283; GO:0021756; GO:0008134; GO:0000050; GO:0047496; GO:0008542,"ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi organization; L-glutamate import; anterior/posterior pattern specification; autophagic vacuole; axon; axon cargo transport; beta-tubulin binding; cell aging; citrulline metabolic process; cytoplasmic vesicle membrane; cytosol; dendrite; determination of adult lifespan; diazepam binding; dopamine receptor signaling pathway; dynein intermediate chain binding; endoplasmic reticulum; endoplasmic reticulum organization; endosomal transport; establishment of mitotic spindle orientation; hormone metabolic process; inclusion body; insulin secretion; iron ion homeostasis; lactate biosynthetic process from pyruvate; late endosome; locomotory behavior; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of neuron apoptotic process; neural plate formation; neuron apoptotic process; neuron development; nucleus; olfactory lobe development; organ development; paraxial mesoderm formation; protein complex; protein import into nucleus; quinolinate biosynthetic process; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; regulation of protein export from nucleus; regulation of protein phosphatase type 2A activity; regulation of synaptic plasticity; response to calcium ion; retrograde vesicle-mediated transport, Golgi to ER; social behavior; spermatogenesis; striatum development; transcription factor binding; urea cycle; vesicle transport along microtubule; visual learning",PF12372;,,,,,,,,,HD_HUMAN,Homo sapiens (Human),"animal organ development [GO:0048513]; apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; mRNA transport [GO:0051028]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; regulation of protein phosphatase type 2A activity [GO:0034047]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]" comp50297_c0_seq1,894,40.3803,0.49532715,23,86,,5.00E-14,Q8N302,Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (hVG5Q) (G patch domain-containing protein 7) (Vasculogenesis gene on 5q protein),Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (hVG5Q) (G patch domain-containing protein 7) (Vasculogenesis gene on 5q protein),GO:0006396; GO:0001525; GO:0007155; GO:0005576; GO:0003676; GO:0048471; GO:0045766; GO:0001938; GO:0001570,RNA processing; angiogenesis; cell adhesion; extracellular region; nucleic acid binding; perinuclear region of cytoplasm; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; vasculogenesis,PF00498;PF01585;,,,,,,,,,AGGF1_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; mRNA processing [GO:0006397]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of RNA splicing [GO:0043484]; RNA processing [GO:0006396]; vasculogenesis [GO:0001570] comp50304_c0_seq1,482,43.5685,0.49649779,14,0,,1.00E-14,Q9QYJ3,DnaJ homolog subfamily B member 1 (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40),DnaJ homolog subfamily B member 1 (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40),GO:0070389; GO:0051085; GO:0005737; GO:0005730; GO:0006950,chaperone cofactor-dependent protein refolding; chaperone mediated protein folding requiring cofactor; cytoplasm; nucleolus; response to stress,PF00226;PF01556;,8.00E-20,CHOYP_LOC100372334.1.1,,,,,,,DNJB1_MOUSE,Mus musculus (Mouse),chaperone cofactor-dependent protein refolding [GO:0070389]; chaperone mediated protein folding requiring cofactor [GO:0051085]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781] comp50308_c0_seq1,245,42.0408,0.47381375,10,43,,2.00E-17,Q9D7V1,SH2 domain-containing protein 4A,SH2 domain-containing protein 4A,GO:0005737; GO:0010923; GO:0005634; GO:0019902,cytoplasm; negative regulation of phosphatase activity; nucleus; phosphatase binding,PF00017;,,,,,,,,,SH24A_MOUSE,Mus musculus (Mouse),negative regulation of phosphatase activity [GO:0010923] comp50310_c0_seq1,761,44.8095,0.76734628,2,104,,3.00E-25,Q62059,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0007507; GO:0005540; GO:0005578; GO:0001657,calcium ion binding; carbohydrate binding; cell adhesion; heart development; hyaluronic acid binding; proteinaceous extracellular matrix; ureteric bud development,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; glial cell migration [GO:0008347]; heart development [GO:0007507]; osteoblast differentiation [GO:0001649]; regulation of phosphoprotein phosphatase activity [GO:0043666]; skeletal system development [GO:0001501]; ureteric bud development [GO:0001657] comp50339_c0_seq1,586,45.7338,0.91555525,39,19,,1.00E-71,Q9H1V8,Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17),Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17),GO:0032328; GO:0030054; GO:0015816; GO:0005887; GO:0015820; GO:0005328; GO:0015824; GO:0008021; GO:0030672,alanine transport; cell junction; glycine transport; integral to plasma membrane; leucine transport; neurotransmitter:sodium symporter activity; proline transport; synaptic vesicle; synaptic vesicle membrane,PF00209;,1.00E-62,CHOYP_S620B.1.1,,,,,,,S6A17_HUMAN,Homo sapiens (Human),alanine transport [GO:0032328]; brain development [GO:0007420]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824] comp50344_c0_seq1,240,43.3333,0.36309482,7,5,,3.00E-32,Q5BJ53,GPN-loop GTPase 2 (ATP-binding domain 1 family member B),GPN-loop GTPase 2 (ATP-binding domain 1 family member B),GO:0005525,GTP binding,PF03029;,4.00E-14,CHOYP_GPN2.1.1,,,,,,,GPN2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp50346_c0_seq1,513,47.3684,1.10791688,9,51,,9.00E-37,P34678,Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (GalNAc-T1) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) (pp-GaNTase 3),Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (GalNAc-T1) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) (pp-GaNTase 3),GO:0000139; GO:0016021; GO:0004653; GO:0018243,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation via threonine,PF00535;PF00652;,,,,,,,,,GALT3_CAEEL,Caenorhabditis elegans,protein O-linked glycosylation via threonine [GO:0018243] comp50353_c0_seq1,1757,38.8731,0.36694451,2251,10573,,0,F1LMZ8,26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6),26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6),GO:0005829; GO:0005634; GO:0022624; GO:0043248; GO:0048863; GO:0006511,cytosol; nucleus; proteasome accessory complex; proteasome assembly; stem cell differentiation; ubiquitin-dependent protein catabolic process,PF01399;,0,CHOYP_LOC100370665.1.1,1.00E-104,ruditapes_c10218,,,,,PSD11_RAT,Rattus norvegicus (Rat),proteasome assembly [GO:0043248]; stem cell differentiation [GO:0048863]; ubiquitin-dependent protein catabolic process [GO:0006511] comp50358_c0_seq1,217,42.8571,1.14739279,1,7,,3.00E-09,Q24040,Protein big brother,Protein big brother,GO:0005634; GO:0046982; GO:0035206; GO:0006357; GO:0003713; GO:0008134,nucleus; protein heterodimerization activity; regulation of hemocyte proliferation; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; transcription factor binding,PF02312;,5.00E-18,CHOYP_PEBB.2.2,2.00E-26,ruditapes_c13419,,,,,BGB_DROME,Drosophila melanogaster (Fruit fly),regulation of hemocyte proliferation [GO:0035206]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp50391_c0_seq1,259,43.2432,1.08334948,0,7,,3.00E-09,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp50429_c0_seq1,329,43.1611,0.52381436,13,6,,3.00E-30,P00918,Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II),Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II),GO:0038166; GO:0045177; GO:0030424; GO:0016323; GO:0015701; GO:0015670; GO:0004089; GO:0005829; GO:0005615; GO:0001822; GO:0005902; GO:0002009; GO:0042475; GO:0006730; GO:0005886; GO:0045780; GO:0032849; GO:2001150; GO:0045672; GO:0044070; GO:0051453; GO:0043627; GO:0009268; GO:0006950; GO:0010043; GO:0046903; GO:0044281; GO:0008270,angiotensin-mediated signaling pathway; apical part of cell; axon; basolateral plasma membrane; bicarbonate transport; carbon dioxide transport; carbonate dehydratase activity; cytosol; extracellular space; kidney development; microvillus; morphogenesis of an epithelium; odontogenesis of dentin-containing tooth; one-carbon metabolic process; plasma membrane; positive regulation of bone resorption; positive regulation of cellular pH reduction; positive regulation of dipeptide transmembrane transport; positive regulation of osteoclast differentiation; regulation of anion transport; regulation of intracellular pH; response to estrogen stimulus; response to pH; response to stress; response to zinc ion; secretion; small molecule metabolic process; zinc ion binding,PF00194;,9.00E-11,CHOYP_CAH2.1.1,,,,,,,CAH2_HUMAN,Homo sapiens (Human),"angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; one-carbon metabolic process [GO:0006730]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]; secretion [GO:0046903]" comp50440_c0_seq1,747,37.8849,0.48834961,359,2020,,7.00E-27,A9UMQ3,LYR motif-containing protein 1,LYR motif-containing protein 1,,,PF05347;,,,2.00E-16,ruditapes_c19282,,,,,LYRM1_XENLA,Xenopus laevis (African clawed frog), comp50498_c0_seq1,652,40.9509,0.95748026,7,6544,female>male,8.00E-07,B2RUY7,von Willebrand factor C domain-containing protein 2-like (Brorin-like),von Willebrand factor C domain-containing protein 2-like (Brorin-like),GO:0032281; GO:0030054; GO:0005615; GO:0030514; GO:0045666; GO:0045202,alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; cell junction; extracellular space; negative regulation of BMP signaling pathway; positive regulation of neuron differentiation; synapse,,,,,,,,,,VWC2L_HUMAN,Homo sapiens (Human),negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of neuron differentiation [GO:0045666] comp50519_c0_seq1,1131,35.1901,0.89710426,1,134,,2.00E-09,O88992,C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1),C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1),GO:0005581; GO:0005737,collagen; cytoplasm,PF00386;PF01391;,,,,,,,,,C1QRF_MOUSE,Mus musculus (Mouse),maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322] comp50519_c0_seq2,1167,35.4756,0.88518443,1,1355,female>male,2.00E-06,Q3Y5Z3,"Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipose most abundant gene transcript 1 protein) (apM-1)","Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipose most abundant gene transcript 1 protein) (apM-1)",GO:0050873; GO:0071944; GO:0009986; GO:0035690; GO:0032869; GO:0005581; GO:0070994; GO:0005783; GO:0005615; GO:0006635; GO:0042593; GO:0006006; GO:0005179; GO:0034383; GO:2000279; GO:0070373; GO:0043124; GO:0043407; GO:0045776; GO:0045599; GO:0045721; GO:0030853; GO:0034115; GO:0050728; GO:0090317; GO:0045715; GO:0010745; GO:0045650; GO:2000590; GO:0050765; GO:2000584; GO:0031953; GO:0014912; GO:0048662; GO:0050805; GO:0045892; GO:0032720; GO:0010804; GO:0048471; GO:0043123; GO:2000481; GO:0010875; GO:0045923; GO:0046326; GO:2000467; GO:0032757; GO:2000478; GO:0071639; GO:0033034; GO:0010739; GO:2000534; GO:0070208; GO:0051260; GO:0072659; GO:0009749; GO:0034612; GO:0033691,"brown fat cell differentiation; cell periphery; cell surface; cellular response to drug; cellular response to insulin stimulus; collagen; detection of oxidative stress; endoplasmic reticulum; extracellular space; fatty acid beta-oxidation; glucose homeostasis; glucose metabolic process; hormone activity; low-density lipoprotein particle clearance; negative regulation of DNA biosynthetic process; negative regulation of ERK1 and ERK2 cascade; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of MAP kinase activity; negative regulation of blood pressure; negative regulation of fat cell differentiation; negative regulation of gluconeogenesis; negative regulation of granulocyte differentiation; negative regulation of heterotypic cell-cell adhesion; negative regulation of inflammatory response; negative regulation of intracellular protein transport; negative regulation of low-density lipoprotein particle receptor biosynthetic process; negative regulation of macrophage derived foam cell differentiation; negative regulation of macrophage differentiation; negative regulation of metanephric mesenchymal cell migration; negative regulation of phagocytosis; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway; negative regulation of protein autophosphorylation; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of synaptic transmission; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor production; negative regulation of tumor necrosis factor-mediated signaling pathway; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cAMP-dependent protein kinase activity; positive regulation of cholesterol efflux; positive regulation of fatty acid metabolic process; positive regulation of glucose import; positive regulation of glycogen (starch) synthase activity; positive regulation of interleukin-8 production; positive regulation of metanephric glomerular visceral epithelial cell development; positive regulation of monocyte chemotactic protein-1 production; positive regulation of myeloid cell apoptotic process; positive regulation of protein kinase A signaling cascade; positive regulation of renal albumin absorption; protein heterotrimerization; protein homooligomerization; protein localization to plasma membrane; response to glucose stimulus; response to tumor necrosis factor; sialic acid binding",PF00386;PF01391;,,,,,,,,,ADIPO_BOVIN,Bos taurus (Bovine),"brown fat cell differentiation [GO:0050873]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; detection of oxidative stress [GO:0070994]; fatty acid beta-oxidation [GO:0006635]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intracellular protein transport [GO:0090317]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metanephric mesenchymal cell migration [GO:2000590]; negative regulation of phagocytosis [GO:0050765]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of receptor binding [GO:1900121]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of fatty acid metabolic process [GO:0045923]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of metanephric glomerular visceral epithelial cell development [GO:2000478]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of renal albumin absorption [GO:2000534]; positive regulation of signal transduction [GO:0009967]; protein heterotrimerization [GO:0070208]; protein homooligomerization [GO:0051260]; protein localization to plasma membrane [GO:0072659]; regulation of glucose metabolic process [GO:0010906]; response to glucose [GO:0009749]; response to tumor necrosis factor [GO:0034612]" comp50528_c0_seq1,1015,39.2118,0.44372554,3576,11649,,9.00E-106,Q0MQI9,"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 24 kDa subunit)","NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 24 kDa subunit)",GO:0051537; GO:0008137; GO:0046872; GO:0006120; GO:0005747,"2 iron, 2 sulfur cluster binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I",,7.00E-63,CHOYP_CRE_00778.1.1,1.00E-140,ruditapes2_c3215,1.00E-64,AM858935.p.cg.6,8,,NDUV2_PANTR,Pan troglodytes (Chimpanzee),"mitochondrial electron transport, NADH to ubiquinone [GO:0006120]" comp50540_c0_seq1,2735,44.4241,0.87730447,13023,13,male>female,0,Q9XTL9,Glycogen phosphorylase (EC 2.4.1.1),Glycogen phosphorylase (EC 2.4.1.1),GO:0050829; GO:0060361; GO:0005980; GO:0008184; GO:0045824; GO:0030170,defense response to Gram-negative bacterium; flight; glycogen catabolic process; glycogen phosphorylase activity; negative regulation of innate immune response; pyridoxal phosphate binding,PF00343;,3.00E-161,CHOYP_LOC100883864.1.1,4.00E-12,ruditapes_c10446,,,,,PYG_DROME,Drosophila melanogaster (Fruit fly),defense response to Gram-negative bacterium [GO:0050829]; determination of adult lifespan [GO:0008340]; flight [GO:0060361]; glycogen catabolic process [GO:0005980]; negative regulation of innate immune response [GO:0045824]; positive regulation of glycogen catabolic process [GO:0045819] comp50557_c0_seq1,882,37.3016,0.50151522,360,2170,,9.00E-51,Q9H446,RWD domain-containing protein 1 (DRG family-regulatory protein 2),RWD domain-containing protein 1 (DRG family-regulatory protein 2),,,PF16543;PF05773;,3.00E-41,CHOYP_LOC100710965.1.1,7.00E-41,ruditapes2_c1640,,,,,RWDD1_HUMAN,Homo sapiens (Human), comp50585_c0_seq1,204,48.5294,0.33634935,2,7,,5.00E-26,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp50630_c0_seq1,1101,35.3315,0.5826993,1379,507,,8.00E-104,Q567I9,Cytochrome b5 domain-containing protein 1,Cytochrome b5 domain-containing protein 1,GO:0020037; GO:0046872,heme binding; metal ion binding,PF00173;,3.00E-143,CHOYP_LOC593741.1.1,6.00E-138,ruditapes2_c2163,1.00E-141,CU983935.p.cg.6,5,,CB5D1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp50635_c0_seq1,516,29.2636,0.18570472,329,1486,,,,,,,,,,,7.00E-13,ruditapes_lrc38206,,,,,,, comp50670_c0_seq1,436,38.3028,0.79095439,2,13,,2.00E-10,P51814,Zinc finger protein 41,Zinc finger protein 41,GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZNF41_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp50689_c1_seq1,351,43.5897,0.78464286,0,24,,2.00E-30,Q91ZY8,E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9),GO:0030054; GO:0005856; GO:0030425; GO:0035544; GO:0045955; GO:0043161; GO:0008021; GO:0016079; GO:0004842; GO:0008270,cell junction; cytoskeleton; dendrite; negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; proteasomal ubiquitin-dependent protein catabolic process; synaptic vesicle; synaptic vesicle exocytosis; ubiquitin-protein ligase activity; zinc ion binding,PF00041;PF00622;PF00643;,9.00E-18,CHOYP_PHUM_PHUM349810.2.2,,,,,,,TRIM9_RAT,Rattus norvegicus (Rat),negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079] comp50838_c1_seq1,358,44.1341,0.28928509,12,0,,2.00E-06,Q5XI14,MCM domain-containing protein 2,MCM domain-containing protein 2,GO:0005524; GO:0003677; GO:0006260,ATP binding; DNA binding; DNA replication,PF00493;,,,,,,,,,MCMD2_RAT,Rattus norvegicus (Rat),DNA replication [GO:0006260] comp51010_c1_seq1,303,40.9241,0.63284582,2,10,,4.00E-13,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp51066_c0_seq1,223,39.9103,0.46961112,0,0,,,,,,,,,5.00E-12,CHOYP_ITIH4.1.1,,,,,,,,, comp51086_c0_seq1,425,43.7647,0.61679878,9,4,,2.00E-39,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,3.00E-37,CHOYP_SACS.3.17,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp51089_c0_seq1,238,51.6807,1.06224098,2,6,,,,,,,,,4.00E-13,CHOYP_LOC100371136.5.5,,,,,,,,, comp51144_c0_seq1,269,43.4944,0.95859313,6,4,,1.00E-11,Q7Z2Q7,Leucine-rich repeat-containing protein 70 (Synleurin),Leucine-rich repeat-containing protein 70 (Synleurin),GO:0016021,integral to membrane,PF13855;,,,,,,,,,LRR70_HUMAN,Homo sapiens (Human),axonogenesis [GO:0007409] comp5114_c0_seq1,274,42.7007,1.04655961,1,4,,4.00E-08,P25119,Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b),Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b),GO:0050779; GO:0008283; GO:0071363; GO:0071222; GO:0006955; GO:0006954; GO:0016021; GO:0008630; GO:0045121; GO:0050728; GO:0043025; GO:0005634; GO:0048471; GO:0051044; GO:0005031; GO:0043196,RNA destabilization; cell proliferation; cellular response to growth factor stimulus; cellular response to lipopolysaccharide; immune response; inflammatory response; integral to membrane; intrinsic apoptotic signaling pathway in response to DNA damage; membrane raft; negative regulation of inflammatory response; neuronal cell body; nucleus; perinuclear region of cytoplasm; positive regulation of membrane protein ectodomain proteolysis; tumor necrosis factor-activated receptor activity; varicosity,PF00020;,,,,,,,,,TNR1B_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipopolysaccharide [GO:0071222]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism development [GO:0007275]; negative regulation of inflammatory response [GO:0050728]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; response to lipopolysaccharide [GO:0032496]; RNA destabilization [GO:0050779] comp51160_c0_seq1,232,46.1207,1.13024488,0,3,,4.00E-11,Q8I136,Polypeptide N-acetylgalactosaminyltransferase 4 (pp-GaNTase 4) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4),Polypeptide N-acetylgalactosaminyltransferase 4 (pp-GaNTase 4) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4),GO:0000139; GO:0016021; GO:0004653; GO:0018243,Golgi membrane; integral to membrane; polypeptide N-acetylgalactosaminyltransferase activity; protein O-linked glycosylation via threonine,PF00535;PF00652;,,,,,,,,,GALT4_CAEEL,Caenorhabditis elegans,protein O-linked glycosylation via threonine [GO:0018243] comp51172_c0_seq1,235,38.2979,0.4958073,1,9,,5.00E-07,Q9H9V4,RING finger protein 122,RING finger protein 122,GO:0005794; GO:0005783; GO:0016021; GO:0008270,Golgi apparatus; endoplasmic reticulum; integral to membrane; zinc ion binding,PF13639;,,,,,,,,,RN122_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp51201_c0_seq1,236,61.4407,0.85772969,0,6,,1.00E-06,P06971,Ferrichrome-iron receptor (Ferric hydroxamate receptor) (Ferric hydroxamate uptake),Ferrichrome-iron receptor (Ferric hydroxamate receptor) (Ferric hydroxamate uptake),GO:0009279; GO:0048037; GO:0016021; GO:0005506; GO:0004872; GO:0044718; GO:0015343; GO:0015643; GO:0046790,cell outer membrane; cofactor binding; integral to membrane; iron ion binding; receptor activity; siderophore transmembrane transport; siderophore transmembrane transporter activity; toxic substance binding; virion binding,PF07715;PF00593;,,,,,,,,,FHUA_ECOLI,Escherichia coli (strain K12),iron ion homeostasis [GO:0055072] comp51247_c0_seq1,560,49.6429,0.37746614,19,0,,4.00E-11,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp51321_c0_seq1,300,41.6667,0.2443209,9,16,,,,,,,,,7.00E-12,CHOYP_BRAFLDRAFT_127093.1.3,,,,,,,,, comp51329_c0_seq1,226,61.0619,1.06325267,4,4,,2.00E-49,Q6A786,Oligoribonuclease (EC 3.1.-.-),Oligoribonuclease (EC 3.1.-.-),GO:0005737; GO:0016896; GO:0003676; GO:0090305,"cytoplasm; exoribonuclease activity, producing 5'-phosphomonoesters; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis",PF00929;,,,,,,,,,ORN_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp51382_c0_seq1,221,44.7964,0.6342987,7,0,,3.00E-07,Q8BGC3,Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT12_MOUSE,Mus musculus (Mouse),creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879] comp51389_c0_seq1,1174,35.4344,0.58599359,75,343,,7.00E-35,Q9DAK9,14 kDa phosphohistidine phosphatase (EC 3.1.3.-) (Phosphohistidine phosphatase 1),14 kDa phosphohistidine phosphatase (EC 3.1.3.-) (Phosphohistidine phosphatase 1),GO:0019855; GO:0005829; GO:2000984; GO:0050860; GO:0051350; GO:0035971; GO:0008969; GO:0004721; GO:2000147; GO:2000249,calcium channel inhibitor activity; cytosol; negative regulation of ATP citrate synthase activity; negative regulation of T cell receptor signaling pathway; negative regulation of lyase activity; peptidyl-histidine dephosphorylation; phosphohistidine phosphatase activity; phosphoprotein phosphatase activity; positive regulation of cell motility; regulation of actin cytoskeleton reorganization,PF05005;,,,,,,,,,PHP14_MOUSE,Mus musculus (Mouse),negative regulation of ATP citrate synthase activity [GO:2000984]; negative regulation of lyase activity [GO:0051350]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-histidine dephosphorylation [GO:0035971]; positive regulation of cell motility [GO:2000147]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein dephosphorylation [GO:0006470]; regulation of actin cytoskeleton reorganization [GO:2000249] comp5139_c0_seq1,210,45.2381,0.75832807,2,0,,4.00E-30,Q10751,Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment),GO:0004180; GO:0016021; GO:0046872; GO:0008237; GO:0008241; GO:0006508,carboxypeptidase activity; integral to membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; proteolysis,PF01401;,2.00E-23,CHOYP_LRP6.3.6,,,,,,,ACE_CHICK,Gallus gallus (Chicken), comp51405_c0_seq1,212,43.3962,0.9274517,1,2,,3.00E-20,P37276,"Dynein heavy chain, cytoplasmic (Dynein heavy chain, cytosolic) (DYHC)","Dynein heavy chain, cytoplasmic (Dynein heavy chain, cytosolic) (DYHC)",GO:0005524; GO:0042623; GO:0005794; GO:0050658; GO:0008088; GO:0005938; GO:0007098; GO:0051642; GO:0040003; GO:0007282; GO:0005868; GO:0048813; GO:0051683; GO:0045198; GO:0040001; GO:0007301; GO:0045169; GO:0048134; GO:0007294; GO:0045172; GO:0008298; GO:0006886; GO:0000776; GO:0051237; GO:0035011; GO:0005874; GO:0003777; GO:0048311; GO:0047497; GO:0007067; GO:0007052; GO:0043148; GO:0016319; GO:0007405; GO:0007312; GO:0030723; GO:0007279; GO:0046604; GO:2001019; GO:0034501; GO:0030071; GO:0030529; GO:0034063,"ATP binding; ATPase activity, coupled; Golgi apparatus; RNA transport; axon cargo transport; cell cortex; centrosome cycle; centrosome localization; chitin-based cuticle development; cystoblast division; cytoplasmic dynein complex; dendrite morphogenesis; establishment of Golgi localization; establishment of epithelial cell apical/basal polarity; establishment of mitotic spindle localization; female germline ring canal formation; fusome; germ-line cyst formation; germarium-derived oocyte fate determination; germline ring canal; intracellular mRNA localization; intracellular protein transport; kinetochore; maintenance of RNA location; melanotic encapsulation of foreign target; microtubule; microtubule motor activity; mitochondrion distribution; mitochondrion transport along microtubule; mitosis; mitotic spindle organization; mitotic spindle stabilization; mushroom body development; neuroblast proliferation; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; ovarian fusome organization; pole cell formation; positive regulation of mitotic centrosome separation; positive regulation of retrograde axon cargo transport; protein localization to kinetochore; regulation of mitotic metaphase/anaphase transition; ribonucleoprotein complex; stress granule assembly",PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,,,,,,,,,DYHC_DROME,Drosophila melanogaster (Fruit fly),axo-dendritic transport [GO:0008088]; border follicle cell migration [GO:0007298]; cellularization [GO:0007349]; centrosome cycle [GO:0007098]; centrosome localization [GO:0051642]; chitin-based cuticle development [GO:0040003]; cystoblast division [GO:0007282]; dendrite morphogenesis [GO:0048813]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment of mitotic spindle localization [GO:0040001]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; female germline ring canal formation [GO:0007301]; fusome organization [GO:0045478]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; intracellular mRNA localization [GO:0008298]; intracellular protein transport [GO:0006886]; maintenance of RNA location [GO:0051237]; melanotic encapsulation of foreign target [GO:0035011]; microtubule-based movement [GO:0007018]; mitochondrion distribution [GO:0048311]; mitochondrion transport along microtubule [GO:0047497]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; mushroom body development [GO:0016319]; neuroblast proliferation [GO:0007405]; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification [GO:0007312]; oogenesis [GO:0048477]; ovarian fusome organization [GO:0030723]; pole cell formation [GO:0007279]; positive regulation of mitotic centrosome separation [GO:0046604]; positive regulation of neuron remodeling [GO:1904801]; protein localization to kinetochore [GO:0034501]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; retrograde axonal transport [GO:0008090]; RNA transport [GO:0050658]; spindle organization [GO:0007051]; stress granule assembly [GO:0034063] comp51427_c0_seq1,355,42.2535,0.25428773,8,5,,4.00E-42,Q86WJ1,Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12) (Amplified in liver cancer protein 1),Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12) (Amplified in liver cancer protein 1),GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0006338; GO:0005737; GO:0000166; GO:0005634; GO:0005886,ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; chromatin remodeling; cytoplasm; nucleotide binding; nucleus; plasma membrane,PF00271;PF00176;,,,,,,,,,CHD1L_HUMAN,Homo sapiens (Human),"cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]" comp51493_c0_seq1,211,30.3318,0,9,3,,,,,,,,,,,3.00E-12,ruditapes_c16730,,,,,,, comp5150_c0_seq1,204,39.2157,0.41000985,5,4,,3.00E-18,Q9Z1N4,"3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP) (scHAL2 analogous 3)","3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP) (scHAL2 analogous 3)",GO:0008441; GO:0004441; GO:0000287; GO:0046854,"3'(2'),5'-bisphosphate nucleotidase activity; inositol-1,4-bisphosphate 1-phosphatase activity; magnesium ion binding; phosphatidylinositol phosphorylation",PF00459;,,,,,,,,,BPNT1_RAT,Rattus norvegicus (Rat),nucleobase-containing compound metabolic process [GO:0006139]; phosphatidylinositol phosphorylation [GO:0046854] comp51516_c0_seq1,361,39.3352,0.43790659,24,0,,2.00E-06,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp51523_c0_seq1,330,38.1818,0.4174061,11,3,,3.00E-14,Q5UPX0,Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13),Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13),GO:0005524; GO:0043140; GO:0006310; GO:0006281; GO:0006260; GO:0003676,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA recombination; DNA repair; DNA replication; nucleic acid binding,PF00270;PF00271;PF16124;PF09382;,,,,,,,,,YR290_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp51572_c0_seq1,643,44.79,1.24324625,219,0,,7.00E-09,P18519,Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD),Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD),GO:0006915; GO:0030154; GO:0016021; GO:0007399; GO:0007165,apoptotic process; cell differentiation; integral to membrane; nervous system development; signal transduction,PF00531;PF00020;,,,,,,,,,TNR16_CHICK,Gallus gallus (Chicken),apoptotic signaling pathway [GO:0097190]; axon guidance [GO:0007411]; circadian regulation of gene expression [GO:0032922]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of neuron projection development [GO:0010977]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; response to lipopolysaccharide [GO:0032496] comp51620_c0_seq1,321,38.9408,2.1975788,22,0,,7.00E-07,Q8IFN0,Uncharacterized protein PFD1115c,Uncharacterized protein PFD1115c,GO:0016021,integral to membrane,,,,,,,,,,YD115_PLAF7,Plasmodium falciparum (isolate 3D7), comp51636_c0_seq1,228,49.5614,0.78917558,6,0,,1.00E-32,Q8TE60,A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,1.00E-31,CHOYP_BRAFLDRAFT_95556.2.2,,,,,,,ATS18_HUMAN,Homo sapiens (Human),eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331] comp51668_c0_seq2,314,44.2675,0.71769576,3,5,,8.00E-35,Q8IUZ5,5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2),5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2),GO:0016829; GO:0008152; GO:0005739; GO:0030170; GO:0008483,lyase activity; metabolic process; mitochondrion; pyridoxal phosphate binding; transaminase activity,PF00202;,5.00E-14,CHOYP_LOC101064182.1.1,,,,,,,AT2L2_HUMAN,Homo sapiens (Human),collagen catabolic process [GO:0030574]; lysine catabolic process [GO:0006554] comp51696_c0_seq1,261,34.8659,1.30091284,2,46,,2.00E-06,A2AJ77,PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12),GO:0003677; GO:0046872; GO:0008168; GO:0022008; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; neurogenesis; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD12_MOUSE,Mus musculus (Mouse),"neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp51726_c0_seq1,1301,36.9716,0.95454602,96,186,,,,,,,,,2.00E-20,CHOYP_LOC100378133.1.1,,,,,,,,, comp51768_c0_seq1,261,37.1648,1.11396193,5,0,,2.00E-11,O43511,Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4),Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4),GO:0016324; GO:0031526; GO:0015108; GO:0016021; GO:0015111; GO:0006885; GO:0032880; GO:0008271; GO:0007605; GO:0015116; GO:0008272,apical plasma membrane; brush border membrane; chloride transmembrane transporter activity; integral to membrane; iodide transmembrane transporter activity; regulation of pH; regulation of protein localization; secondary active sulfate transmembrane transporter activity; sensory perception of sound; sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A4_HUMAN,Homo sapiens (Human),bicarbonate transport [GO:0015701]; inorganic anion transport [GO:0015698]; ion transport [GO:0006811]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; regulation of pH [GO:0006885]; regulation of protein localization [GO:0032880]; sensory perception of sound [GO:0007605]; sulfate transport [GO:0008272] comp51776_c0_seq1,331,40.1813,0.30319911,8,24,,2.00E-16,Q5RCW2,"Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (Polynucleotide phosphorylase 1) (PNPase 1)","Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (Polynucleotide phosphorylase 1) (PNPase 1)",GO:0000175; GO:0034599; GO:0016020; GO:0035198; GO:0000965; GO:0000964; GO:0045025; GO:0005758; GO:0000958; GO:0097222; GO:0070584; GO:0071850; GO:0045926; GO:0071042; GO:0034046; GO:0008266; GO:0004654; GO:0061014; GO:2000627; GO:0000962; GO:0070207; GO:0035928; GO:0043457; GO:2000772,3'-5'-exoribonuclease activity; cellular response to oxidative stress; membrane; miRNA binding; mitochondrial RNA 3'-end processing; mitochondrial RNA 5'-end processing; mitochondrial degradosome; mitochondrial intermembrane space; mitochondrial mRNA catabolic process; mitochondrial mRNA polyadenylation; mitochondrion morphogenesis; mitotic cell cycle arrest; negative regulation of growth; nuclear polyadenylation-dependent mRNA catabolic process; poly(G) RNA binding; poly(U) RNA binding; polyribonucleotide nucleotidyltransferase activity; positive regulation of mRNA catabolic process; positive regulation of miRNA catabolic process; positive regulation of mitochondrial RNA catabolic process; protein homotrimerization; rRNA import into mitochondrion; regulation of cellular respiration; regulation of cellular senescence,PF00013;PF03726;PF01138;PF03725;PF00575;,,,,,,,,,PNPT1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular response to oxidative stress [GO:0034599]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mitotic cell cycle arrest [GO:0071850]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928] comp51778_c0_seq1,244,37.7049,0.69603442,0,0,,4.00E-10,Q8C0K5,Graves disease carrier protein homolog (GDC) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16),Graves disease carrier protein homolog (GDC) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16),GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,,,,,,,,,GDC_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transmembrane transport [GO:0055085] comp51778_c0_seq2,269,37.1747,0.75601045,3,0,,6.00E-07,Q9BV35,Calcium-binding mitochondrial carrier protein SCaMC-3 (Mitochondrial ATP-Mg/Pi carrier protein 2) (Mitochondrial Ca(2+)-dependent solute carrier protein 2) (Small calcium-binding mitochondrial carrier protein 3) (Solute carrier family 25 member 23),Calcium-binding mitochondrial carrier protein SCaMC-3 (Mitochondrial ATP-Mg/Pi carrier protein 2) (Mitochondrial Ca(2+)-dependent solute carrier protein 2) (Small calcium-binding mitochondrial carrier protein 3) (Solute carrier family 25 member 23),GO:0005509; GO:0016021; GO:0005743; GO:0055085,calcium ion binding; integral to membrane; mitochondrial inner membrane; transmembrane transport,PF13202;PF13499;PF00153;,,,,,,,,,SCMC3_HUMAN,Homo sapiens (Human),adenine nucleotide transport [GO:0051503]; cellular response to calcium ion [GO:0071277]; regulation of cellular respiration [GO:0043457]; regulation of oxidative phosphorylation [GO:0002082]; regulation of sequestering of calcium ion [GO:0051282]; translation [GO:0006412]; transmembrane transport [GO:0055085]; urea homeostasis [GO:0097274] comp51820_c0_seq1,310,35.4839,0.42530357,6,58,,2.00E-09,Q8BT51,"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (Coiled-coil-helix-coiled-coil-helix domain-containing protein 8)","Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (Coiled-coil-helix-coiled-coil-helix domain-containing protein 8)",GO:0005739,mitochondrion,PF06747;,,,,,,,,,CHCH8_MOUSE,Mus musculus (Mouse),mitochondrial respiratory chain complex IV assembly [GO:0033617] comp5183_c0_seq1,202,68.3168,1.066875,0,1,,5.00E-13,Q4L8G8,Putative formate dehydrogenase SH0748 (EC 1.2.1.2),Putative formate dehydrogenase SH0748 (EC 1.2.1.2),GO:0051537; GO:0051539; GO:0009055; GO:0008863; GO:0015942; GO:0030151,"2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; electron carrier activity; formate dehydrogenase (NAD+) activity; formate metabolic process; molybdenum ion binding",PF12838;PF04879;PF00384;PF01568;PF10588;,,,,,,,,,FDHL_STAHJ,Staphylococcus haemolyticus (strain JCSC1435),formate metabolic process [GO:0015942] comp51862_c0_seq1,267,46.0674,0.63810419,9,50,,2.00E-09,Q60584,F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6),F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6),GO:0005737,cytoplasm,PF12937;PF00400;,,,,,,,,,FBXW2_MOUSE,Mus musculus (Mouse), comp51875_c0_seq1,257,41.2451,0.73900152,7,0,,,,,,,,,7.00E-11,CHOYP_TRIADDRAFT_51756.1.1,,,,,,,,, comp51877_c0_seq1,283,42.0495,0.32090796,6,1,,2.00E-07,Q17RM4,Coiled-coil domain-containing protein 142,Coiled-coil domain-containing protein 142,,,,,,,,,,,,CC142_HUMAN,Homo sapiens (Human), comp51922_c0_seq1,232,32.3276,0.49929499,7,0,,8.00E-07,Q66JZ4,"T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)","T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)",GO:0005739,mitochondrion,PF14687;PF14688;,,,,,,,,,CC023_MOUSE,Mus musculus (Mouse), comp51940_c0_seq1,373,34.8525,0.84807866,4,12,,1.00E-41,Q24212,Protein stoned-B (Stn-B) (StonedB),Protein stoned-B (Stn-B) (StonedB),GO:0030054; GO:0030131; GO:0030139; GO:0006886; GO:0007269; GO:0005886; GO:1900242; GO:0008021; GO:0016183,cell junction; clathrin adaptor complex; endocytic vesicle; intracellular protein transport; neurotransmitter secretion; plasma membrane; regulation of synaptic vesicle endocytosis; synaptic vesicle; synaptic vesicle coating,PF00928;,2.00E-65,CHOYP_STNB.1.1,,,,,,,STNB_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle endocytosis [GO:1900242]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; vesicle coating [GO:0006901] comp51992_c0_seq1,205,45.8537,0.83969389,2,5,,4.00E-10,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp51994_c0_seq1,490,45.102,0.72633439,19,0,,5.00E-12,P17213,Bactericidal permeability-increasing protein (BPI) (CAP 57),Bactericidal permeability-increasing protein (BPI) (CAP 57),GO:0005737; GO:0042742; GO:0005576; GO:0006955; GO:0005887; GO:0001530; GO:0032715; GO:0032717; GO:0043031; GO:0032720,cytoplasm; defense response to bacterium; extracellular region; immune response; integral to plasma membrane; lipopolysaccharide binding; negative regulation of interleukin-6 production; negative regulation of interleukin-8 production; negative regulation of macrophage activation; negative regulation of tumor necrosis factor production,PF01273;PF02886;,,,,,,,,,BPI_HUMAN,Homo sapiens (Human),defense response to Gram-negative bacterium [GO:0050829]; immune response [GO:0006955]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of macrophage activation [GO:0043031]; negative regulation of tumor necrosis factor production [GO:0032720] comp52032_c0_seq1,238,42.0168,0.59281741,3,4,,3.00E-15,P42893,Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71),GO:0006915; GO:0005769; GO:0009897; GO:0016021; GO:0046872; GO:0004222; GO:0045745; GO:0030819; GO:0010613; GO:0001921; GO:0042803; GO:0016485; GO:0006508; GO:0070372; GO:0008217; GO:0042312; GO:0046686; GO:0042493; GO:0001666; GO:0035994; GO:0030141,apoptotic process; early endosome; external side of plasma membrane; integral to membrane; metal ion binding; metalloendopeptidase activity; positive regulation of G-protein coupled receptor protein signaling pathway; positive regulation of cAMP biosynthetic process; positive regulation of cardiac muscle hypertrophy; positive regulation of receptor recycling; protein homodimerization activity; protein processing; proteolysis; regulation of ERK1 and ERK2 cascade; regulation of blood pressure; regulation of vasodilation; response to cadmium ion; response to drug; response to hypoxia; response to muscle stretch; secretory granule,PF01431;PF05649;,,,,,,,,,ECE1_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of vasodilation [GO:0042312]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994] comp52057_c0_seq1,1044,37.6437,0.89800093,6,242,,3.00E-11,Q9I927,Fucolectin-5,Fucolectin-5,GO:0005509; GO:0007155; GO:0005615; GO:0042806; GO:0010185; GO:0001868,"calcium ion binding; cell adhesion; extracellular space; fucose binding; regulation of cellular defense response; regulation of complement activation, lectin pathway",PF00754;,,,,,,,,,FUCL5_ANGJA,Anguilla japonica (Japanese eel),"regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088]" comp52064_c0_seq1,265,36.9811,0.78072391,2,20,,3.00E-14,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp52116_c0_seq1,262,62.9771,1.16270483,0,7,,7.00E-54,B9MEQ7,CTP synthase (EC 6.3.4.2) (CTP synthetase) (UTP--ammonia ligase),CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase),GO:0044210; GO:0005524; GO:0003883; GO:0006541,'de novo' CTP biosynthetic process; ATP binding; CTP synthase activity; glutamine metabolic process,PF06418;PF00117;,,,,,,,,,PYRG_ACIET,Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)),'de novo' CTP biosynthetic process [GO:0044210]; glutamine metabolic process [GO:0006541] comp52229_c0_seq2,545,36.3303,0.50654742,0,0,,2.00E-14,Q3UI66,Coiled-coil domain-containing protein 34,Coiled-coil domain-containing protein 34,,,,6.00E-22,CHOYP_LOC100494757.1.1,,,,,,,CCD34_MOUSE,Mus musculus (Mouse), comp52262_c0_seq1,227,44.4934,0,0,12,,6.00E-09,Q8I335,"Translation factor GUF1 homolog, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1 homolog) (Ribosomal back-translocase)","Translation factor GUF1 homolog, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1 homolog) (Ribosomal back-translocase)",GO:0005525; GO:0006184; GO:0003924; GO:0020011; GO:0005743; GO:0006412,GTP binding; GTP catabolic process; GTPase activity; apicoplast; mitochondrial inner membrane; translation,PF00679;PF06421;,,,,,,,,,GUF1_PLAF7,Plasmodium falciparum (isolate 3D7),translation [GO:0006412] comp52312_c1_seq1,308,53.8961,0.44854588,8,6,,5.00E-12,A2VCL2,Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene),Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene),,,,1.00E-52,CHOYP_LOC579367.1.1,,,,,,,CC162_HUMAN,Homo sapiens (Human), comp52322_c0_seq1,462,37.013,0.4904684,6,118,,2.00E-19,P05413,"Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP) (Mammary-derived growth inhibitor) (MDGI) (Muscle fatty acid-binding protein) (M-FABP)","Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP) (Mammary-derived growth inhibitor) (MDGI) (Muscle fatty acid-binding protein) (M-FABP)",GO:0005829; GO:0006631; GO:0050543; GO:0008289; GO:0005324; GO:0008285; GO:0042493; GO:0070542; GO:0032868; GO:0016528,cytosol; fatty acid metabolic process; icosatetraenoic acid binding; lipid binding; long-chain fatty acid transporter activity; negative regulation of cell proliferation; response to drug; response to fatty acid; response to insulin stimulus; sarcoplasm,PF00061;,2.00E-14,CHOYP_LOC100057425.1.1,,,,,,,FABPH_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid import [GO:0044539]; negative regulation of cell proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433] comp52360_c0_seq1,221,46.6063,0.59541449,3,6,,,,,,,,,4.00E-13,CHOYP_CRE_02254.1.1,,,,,,,,, comp52405_c0_seq1,316,43.3544,0.67851707,6,9,,1.00E-18,P53356,Tyrosine-protein kinase HTK16 (EC 2.7.10.2),Tyrosine-protein kinase HTK16 (EC 2.7.10.2),GO:0005524; GO:0004715; GO:0018108,ATP binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF12796;PF07714;PF00017;,,,,,,,,,HTK16_HYDVU,Hydra vulgaris (Hydra) (Hydra attenuata), comp52408_c0_seq1,251,45.0199,1.02697555,3,6,,3.00E-11,Q6MZM0,Hephaestin-like protein 1 (EC 1.-.-.-),Hephaestin-like protein 1 (EC 1.-.-.-),GO:0005507; GO:0006825; GO:0004322; GO:0016021,copper ion binding; copper ion transport; ferroxidase activity; integral to membrane,PF07731;PF07732;,,,,,,,,,HPHL1_HUMAN,Homo sapiens (Human),copper ion transport [GO:0006825]; oxidation-reduction process [GO:0055114] comp52425_c0_seq2,493,40.9736,0.38986054,7,0,,1.00E-61,Q68FE2,Autophagy-related protein 9A (APG9-like 1),Autophagy-related protein 9A (APG9-like 1),GO:0005794; GO:0005776; GO:0000045; GO:0000421; GO:0031410; GO:0045087; GO:0016021; GO:0031902; GO:0034067; GO:0015031,Golgi apparatus; autophagic vacuole; autophagic vacuole assembly; autophagic vacuole membrane; cytoplasmic vesicle; innate immune response; integral to membrane; late endosome membrane; protein localization to Golgi apparatus; protein transport,PF04109;,1.00E-48,CHOYP_LOC100561934.1.1,,,,,,,ATG9A_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; innate immune response [GO:0045087]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; negative regulation of interferon-beta production [GO:0032688]; piecemeal microautophagy of nucleus [GO:0034727]; protein localization to Golgi apparatus [GO:0034067]; protein localization to pre-autophagosomal structure [GO:0034497]; protein transport [GO:0015031] comp52441_c0_seq1,239,42.2594,0.47619881,2,0,,7.00E-06,Q84M24,ABC transporter A family member 1 (ABC transporter ABCA.1) (AtABCA1) (ABC one homolog protein 1) (AtAOH1),ABC transporter A family member 1 (ABC transporter ABCA.1) (AtABCA1) (ABC one homolog protein 1) (AtAOH1),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0006810; GO:0005774,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; transport; vacuolar membrane,PF00005;,,,,,,,,,AB1A_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869] comp52450_c0_seq1,237,46.8354,0.46364462,6,0,,1.00E-06,Q9BX84,Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6),Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6),GO:0005524; GO:0016324; GO:0031526; GO:0005262; GO:0016021; GO:0046872; GO:0004674; GO:0009636,ATP binding; apical plasma membrane; brush border membrane; calcium channel activity; integral to membrane; metal ion binding; protein serine/threonine kinase activity; response to toxic substance,PF02816;PF00520;PF16519;,,,,,,,,,TRPM6_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636] comp52482_c0_seq1,246,58.5366,0.9196703,0,7,,4.00E-08,Q3LXA3,Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)],Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)],GO:0005524; GO:0034012; GO:0005829; GO:0006071; GO:0004371; GO:0045087; GO:0046872; GO:0050354,ATP binding; FAD-AMP lyase (cyclizing) activity; cytosol; glycerol metabolic process; glycerone kinase activity; innate immune response; metal ion binding; triokinase activity,PF02733;PF02734;,,,,,,,,,DHAK_HUMAN,Homo sapiens (Human),carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol metabolic process [GO:0006071]; innate immune response [GO:0045087]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088] comp52494_c0_seq1,218,61.9266,1.3465369,0,7,,6.00E-11,P99173,Zinc-type alcohol dehydrogenase-like protein SA1988,Zinc-type alcohol dehydrogenase-like protein SA1988,GO:0016491; GO:0008270,oxidoreductase activity; zinc ion binding,PF08240;PF00107;,,,,,,,,,ZDH1_STAAN,Staphylococcus aureus (strain N315), comp52508_c0_seq1,282,50.3546,0.67704201,9,0,,3.00E-41,Q62910,"Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)","Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)",GO:0003723; GO:0017124; GO:0007420; GO:0005737; GO:0006897; GO:0043005; GO:0000166; GO:0046856; GO:0034595; GO:0004439; GO:0014015; GO:0048260; GO:0043234; GO:0032403; GO:0034097; GO:0032526,"RNA binding; SH3 domain binding; brain development; cytoplasm; endocytosis; neuron projection; nucleotide binding; phosphatidylinositol dephosphorylation; phosphatidylinositol phosphate 5-phosphatase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; positive regulation of gliogenesis; positive regulation of receptor-mediated endocytosis; protein complex; protein complex binding; response to cytokine stimulus; response to retinoic acid",PF08952;PF03372;PF02383;,3.00E-35,CHOYP_SYNJ1.1.1,,,,,,,SYNJ1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488] comp52542_c0_seq1,288,44.4444,1.06486177,0,13,,6.00E-21,Q90953,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp52585_c0_seq1,466,45.279,0.97663661,0,149,,1.00E-29,Q5R8A5,Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],GO:0005509; GO:0005544; GO:0016023; GO:0004622; GO:0004623; GO:0009395,calcium ion binding; calcium-dependent phospholipid binding; cytoplasmic membrane-bounded vesicle; lysophospholipase activity; phospholipase A2 activity; phospholipid catabolic process,PF00168;PF01735;,3.00E-32,CHOYP_PA24A.2.3,,,,,,,PA24A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),phospholipid catabolic process [GO:0009395] comp52647_c0_seq1,338,45.858,0.22653055,11,4,,7.00E-21,Q9Y5Q9,General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma),GO:0042791; GO:0003677; GO:0005654; GO:0042797; GO:0000127,5S class rRNA transcription from RNA polymerase III type 1 promoter; DNA binding; nucleoplasm; tRNA transcription from RNA polymerase III promoter; transcription factor TFIIIC complex,PF13181;,4.00E-15,CHOYP_TF3C3.2.3,,,,,,,TF3C3_HUMAN,Homo sapiens (Human),"5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]" comp52655_c0_seq1,512,50.3906,0.83359731,12,3,,2.00E-48,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp52700_c0_seq1,641,43.9938,0.35585876,25,0,,2.00E-47,Q96AE7,Tetratricopeptide repeat protein 17 (TPR repeat protein 17),Tetratricopeptide repeat protein 17 (TPR repeat protein 17),,,PF13181;,,,,,,,,,TTC17_HUMAN,Homo sapiens (Human),actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] comp52714_c0_seq1,278,35.6115,0.45775818,11,0,,4.00E-19,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp52716_c0_seq1,341,42.2287,0.19853112,17,0,,8.00E-07,Q96S38,Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein),Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein),GO:0005524; GO:0005769; GO:0016020; GO:0035091; GO:0004674; GO:0007165,ATP binding; early endosome; membrane; phosphatidylinositol binding; protein serine/threonine kinase activity; signal transduction,PF04212;PF00069;PF00787;,,,,,,,,,KS6C1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp52814_c1_seq1,239,43.9331,0.96001681,5,7,,7.00E-11,O32231,Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog),Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog),GO:0003723; GO:0016070; GO:0005737; GO:0008859; GO:0090305,RNA binding; RNA metabolic process; cytoplasm; exoribonuclease II activity; nucleic acid phosphodiester bond hydrolysis,PF08206;PF00575;,,,,,,,,,RNR_BACSU,Bacillus subtilis (strain 168),RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364] comp52818_c0_seq1,272,45.5882,0.49831182,4,7,,5.00E-48,Q93099,"Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)","Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)",GO:0006559; GO:0034641; GO:0005829; GO:0004411; GO:0046872; GO:0006572,"L-phenylalanine catabolic process; cellular nitrogen compound metabolic process; cytosol; homogentisate 1,2-dioxygenase activity; metal ion binding; tyrosine catabolic process",PF04209;,9.00E-48,CHOYP_BRAFLDRAFT_73486.1.1,,,,,,,HGD_HUMAN,Homo sapiens (Human),L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp52843_c0_seq1,311,45.3376,0.25679278,7,4,,2.00E-28,P15064,Ras-like protein rasG,Ras-like protein rasG,GO:0005525; GO:0003924; GO:0007265; GO:0032861; GO:0007190; GO:0007188; GO:0031152; GO:0000902; GO:0008283; GO:0031589; GO:0043327; GO:0000281; GO:0045335; GO:0005886; GO:0030828; GO:0008284; GO:0031284; GO:0043552; GO:0050927; GO:0051897; GO:0046586; GO:0001932,GTP binding; GTPase activity; Ras protein signal transduction; activation of Rap GTPase activity; activation of adenylate cyclase activity; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; aggregation involved in sorocarp development; cell morphogenesis; cell proliferation; cell-substrate adhesion; chemotaxis to cAMP; mitotic cytokinesis; phagocytic vesicle; plasma membrane; positive regulation of cGMP biosynthetic process; positive regulation of cell proliferation; positive regulation of guanylate cyclase activity; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of positive chemotaxis; positive regulation of protein kinase B signaling cascade; regulation of calcium-dependent cell-cell adhesion; regulation of protein phosphorylation,PF00071;,6.00E-13,CHOYP_RAS.1.1,,,,,,,RASG_DICDI,Dictyostelium discoideum (Slime mold),activation of adenylate cyclase activity [GO:0007190]; activation of GTPase activity [GO:0090630]; activation of protein kinase B activity [GO:0032148]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; aggregation involved in sorocarp development [GO:0031152]; asexual reproduction [GO:0019954]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; chemotaxis to cAMP [GO:0043327]; chemotaxis to folate [GO:0043326]; macropinocytosis [GO:0044351]; mitotic cytokinesis [GO:0000281]; negative regulation of MAP kinase activity [GO:0043407]; positive regulation of asexual reproduction [GO:1903666]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; Ras protein signal transduction [GO:0007265]; regulation of calcium-dependent cell-cell adhesion [GO:0046586]; regulation of protein phosphorylation [GO:0001932] comp52939_c0_seq1,205,35.122,0.31815429,7,0,,2.00E-07,P47843,"Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)","Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)",GO:0005355; GO:0015758; GO:0016021,glucose transmembrane transporter activity; glucose transport; integral to membrane,PF00083;,,,,,,,,,GTR3_SHEEP,Ovis aries (Sheep),glucose transmembrane transport [GO:1904659] comp52945_c0_seq1,239,38.4937,0.7076291,5,4,,5.00E-06,Q9TZM3,"Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)","Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)",GO:0005524; GO:0005525; GO:0005794; GO:0048846; GO:0034613; GO:0046872; GO:0043025; GO:0004674; GO:0034976; GO:0006979; GO:0007264; GO:0048489,ATP binding; GTP binding; Golgi apparatus; axon extension involved in axon guidance; cellular protein localization; metal ion binding; neuronal cell body; protein serine/threonine kinase activity; response to endoplasmic reticulum stress; response to oxidative stress; small GTPase mediated signal transduction; synaptic vesicle transport,PF12796;PF16095;PF13855;PF00069;PF08477;,,,,,,,,,LRK1_CAEEL,Caenorhabditis elegans,axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489] comp53011_c0_seq1,254,57.0866,1.11716017,3,9,,4.00E-14,P34699,DNA polymerase III subunit alpha (EC 2.7.7.7),DNA polymerase III subunit alpha (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0006260; GO:0003887; GO:0005737,3'-5' exonuclease activity; DNA binding; DNA replication; DNA-directed DNA polymerase activity; cytoplasm,PF07733;PF14579;PF02811;PF01336;,,,,,,,,,DPO3A_SACEN,Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338),DNA replication [GO:0006260] comp53020_c0_seq1,384,46.6146,0.24774943,5,0,,3.00E-46,Q6PBY7,Trafficking protein particle complex subunit 13,Trafficking protein particle complex subunit 13,,,PF06159;,4.00E-29,CHOYP_BRAFLDRAFT_282065.2.2,,,,,,,CE044_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp53044_c0_seq1,373,41.8231,0.4305952,3,2,,2.00E-45,P36406,E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23),E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23),GO:0019003; GO:0005525; GO:0003924; GO:0000139; GO:0008047; GO:0005765; GO:0019048; GO:0005634; GO:0007264; GO:0004842; GO:0008270,GDP binding; GTP binding; GTPase activity; Golgi membrane; enzyme activator activity; lysosomal membrane; modulation by virus of host morphology or physiology; nucleus; small GTPase mediated signal transduction; ubiquitin-protein ligase activity; zinc ion binding,PF00025;PF00643;PF14634;,2.00E-32,CHOYP_TRI23.4.7,,,,,,,TRI23_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264]; viral process [GO:0016032] comp53070_c0_seq1,208,60.0962,0.94748857,9,74,,,,,,,,,5.00E-12,CHOYP_LOC100353582.2.2,,,,,,,,, comp53072_c0_seq1,248,44.3548,0.33832072,5,0,,3.00E-09,Q5EA42,Abhydrolase domain-containing protein 2 (EC 3.1.1.-),Monoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2),GO:0004091; GO:0016021; GO:0030336; GO:0009611,carboxylesterase activity; integral to membrane; negative regulation of cell migration; response to wounding,PF00561;,,,,,,,,,ABHD2_BOVIN,Bos taurus (Bovine),acylglycerol catabolic process [GO:0046464]; negative regulation of cell migration [GO:0030336]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; steroid hormone mediated signaling pathway [GO:0043401] comp5308_c0_seq1,212,48.5849,1.0808203,6,0,,,,,,,,,,,4.00E-11,ruditapes_c12650,,,,,,, comp53131_c0_seq1,267,46.4419,0.49854539,9,0,,,,,,,,,4.00E-52,CHOYP_PHUM_PHUM035190.1.1,,,,,,,,, comp53131_c1_seq1,305,45.2459,0.45769723,8,0,,2.00E-30,Q9Y4E6,WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG),WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG),,,PF00400;,,,,,,,,,WDR7_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244] comp53165_c0_seq1,229,44.1048,0.63890107,7,0,,8.00E-11,Q9LQV2,RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1),RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1),GO:0003723; GO:0003968; GO:0006952; GO:0031047; GO:0060148; GO:0009751; GO:0009615; GO:0010025,RNA binding; RNA-directed RNA polymerase activity; defense response; gene silencing by RNA; positive regulation of posttranscriptional gene silencing; response to salicylic acid stimulus; response to virus; wax biosynthetic process,PF05183;,,,,,,,,,RDR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),defense response [GO:0006952]; positive regulation of posttranscriptional gene silencing [GO:0060148]; production of siRNA involved in RNA interference [GO:0030422]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; wax biosynthetic process [GO:0010025] comp5318_c0_seq1,237,38.8186,0.59028829,1,2,,4.00E-09,P55159,Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (Serum aryldialkylphosphatase 1),Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (Serum aryldialkylphosphatase 1),GO:0019439; GO:0004063; GO:0004064; GO:0005509; GO:0046395; GO:0008203; GO:0005615; GO:0043231; GO:0006629; GO:0046434; GO:0046470; GO:0005543; GO:0051099; GO:0010875; GO:0032411; GO:0009636; GO:0034366,aromatic compound catabolic process; aryldialkylphosphatase activity; arylesterase activity; calcium ion binding; carboxylic acid catabolic process; cholesterol metabolic process; extracellular space; intracellular membrane-bounded organelle; lipid metabolic process; organophosphate catabolic process; phosphatidylcholine metabolic process; phospholipid binding; positive regulation of binding; positive regulation of cholesterol efflux; positive regulation of transporter activity; response to toxic substance; spherical high-density lipoprotein particle,PF01731;,,,,,,,,,PON1_RAT,Rattus norvegicus (Rat),aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; cholesterol metabolic process [GO:0008203]; lipid metabolic process [GO:0006629]; organophosphate catabolic process [GO:0046434]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of binding [GO:0051099]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transporter activity [GO:0032411]; response to fatty acid [GO:0070542]; response to fluoride [GO:1902617]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636] comp53190_c1_seq1,202,38.1188,0.71179865,1,2,,4.00E-13,Q8BGY9,High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7),High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7),GO:0008292; GO:0033265; GO:0015220; GO:0005307; GO:0016021; GO:0007274; GO:0043025; GO:0005886; GO:0007271,"acetylcholine biosynthetic process; choline binding; choline transmembrane transporter activity; choline:sodium symporter activity; integral to membrane; neuromuscular synaptic transmission; neuronal cell body; plasma membrane; synaptic transmission, cholinergic",PF00474;,,,,,,,,,SC5A7_MOUSE,Mus musculus (Mouse),"acetylcholine biosynthetic process [GO:0008292]; choline transport [GO:0015871]; neuromuscular synaptic transmission [GO:0007274]; synaptic transmission, cholinergic [GO:0007271]" comp53225_c0_seq1,428,46.028,0.49197516,18,0,,5.00E-34,P23249,Putative helicase MOV-10 (EC 3.6.4.13) (Moloney leukemia virus 10 protein),Putative helicase MOV-10 (EC 3.6.4.13) (Moloney leukemia virus 10 protein),GO:0005524; GO:0003723; GO:0000932; GO:0004386; GO:0035279,ATP binding; RNA binding; cytoplasmic mRNA processing body; helicase activity; mRNA cleavage involved in gene silencing by miRNA,,4.00E-11,CHOYP_BRAFLDRAFT_119350.1.1,,,,,,,MOV10_MOUSE,Mus musculus (Mouse),gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279] comp53415_c0_seq1,398,45.4774,0.56486843,3,3,,8.00E-11,P19137,Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha),GO:0060445; GO:0007155; GO:0007166; GO:0005911; GO:0060441; GO:0045198; GO:0005201; GO:0043208; GO:0005606; GO:0002011; GO:0031175; GO:0030155; GO:0030334; GO:0045995; GO:0061304,branching involved in salivary gland morphogenesis; cell adhesion; cell surface receptor signaling pathway; cell-cell junction; epithelial tube branching involved in lung morphogenesis; establishment of epithelial cell apical/basal polarity; extracellular matrix structural constituent; glycosphingolipid binding; laminin-1 complex; morphogenesis of an epithelial sheet; neuron projection development; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; retinal blood vessel morphogenesis,PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;,,,,,,,,,LAMA1_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888] comp53423_c0_seq1,495,47.6768,0.5184045,4,37,,3.00E-60,Q01240,60 kDa neurofilament protein (NF60),60 kDa neurofilament protein (NF60),GO:0005882; GO:0005198,intermediate filament; structural molecule activity,PF00038;,9.00E-45,CHOYP_NF70.1.4,,,,,,,NF60_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp53469_c1_seq1,341,49.5601,0.28747796,11,0,,9.00E-08,Q9R0M3,Sushi-repeat-containing protein SRPX (DRS protein),Sushi-repeat-containing protein SRPX (DRS protein),GO:0005776; GO:0006914; GO:0009986; GO:0005783; GO:0060244; GO:0001845; GO:2001241; GO:0034976,autophagic vacuole; autophagy; cell surface; endoplasmic reticulum; negative regulation of cell proliferation involved in contact inhibition; phagolysosome assembly; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; response to endoplasmic reticulum stress,PF13778;PF02494;PF00084;,,,,,,,,,SRPX_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; phagolysosome assembly [GO:0001845]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; response to endoplasmic reticulum stress [GO:0034976] comp53471_c0_seq1,262,45.4198,0.44830199,4,9,,1.00E-10,P30994,5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (5-HT-2F) (Serotonin receptor 2B) (Stomach fundus serotonin receptor),5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (5-HT-2F) (Serotonin receptor 2B) (Stomach fundus serotonin receptor),GO:0070371; GO:0001965; GO:0002031; GO:0005099; GO:0007610; GO:0006182; GO:0005262; GO:0019722; GO:0003300; GO:0030054; GO:0071502; GO:0005737; GO:0008144; GO:0048598; GO:0003007; GO:0005887; GO:0014827; GO:0043066; GO:0010507; GO:0001755; GO:0043005; GO:0014065; GO:0004435; GO:0016310; GO:0005886; GO:0070374; GO:0043123; GO:0051781; GO:0001819; GO:0050715; GO:0001938; GO:0051000; GO:0010513; GO:0070528; GO:0007205; GO:0050795; GO:0051209; GO:0042493; GO:0051378; GO:0004993; GO:0045202; GO:0042310,ERK1 and ERK2 cascade; G-protein alpha-subunit binding; G-protein coupled receptor internalization; Ras GTPase activator activity; behavior; cGMP biosynthetic process; calcium channel activity; calcium-mediated signaling; cardiac muscle hypertrophy; cell junction; cellular response to temperature stimulus; cytoplasm; drug binding; embryonic morphogenesis; heart morphogenesis; integral to plasma membrane; intestine smooth muscle contraction; negative regulation of apoptotic process; negative regulation of autophagy; neural crest cell migration; neuron projection; phosphatidylinositol 3-kinase cascade; phosphatidylinositol phospholipase C activity; phosphorylation; plasma membrane; positive regulation of ERK1 and ERK2 cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cell division; positive regulation of cytokine production; positive regulation of cytokine secretion; positive regulation of endothelial cell proliferation; positive regulation of nitric-oxide synthase activity; positive regulation of phosphatidylinositol biosynthetic process; protein kinase C signaling cascade; protein kinase C-activating G-protein coupled receptor signaling pathway; regulation of behavior; release of sequestered calcium ion into cytosol; response to drug; serotonin binding; serotonin receptor activity; synapse; vasoconstriction,PF00001;,,,,,,,,,5HT2B_RAT,Rattus norvegicus (Rat),behavior [GO:0007610]; calcium-mediated signaling [GO:0019722]; cardiac muscle hypertrophy [GO:0003300]; cellular response to amine stimulus [GO:0071418]; cellular response to serotonin [GO:1904015]; cellular response to temperature stimulus [GO:0071502]; cGMP biosynthetic process [GO:0006182]; embryonic morphogenesis [GO:0048598]; ERK1 and ERK2 cascade [GO:0070371]; G-protein coupled receptor signaling pathway [GO:0007186]; heart morphogenesis [GO:0003007]; hepatic stellate cell activation [GO:0035733]; inositol phosphate metabolic process [GO:0043647]; intestine smooth muscle contraction [GO:0014827]; ion transmembrane transport [GO:0034220]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; neural crest cell differentiation [GO:0014033]; neural crest cell migration [GO:0001755]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of behavior [GO:0050795]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; serotonin receptor signaling pathway [GO:0007210]; vasoconstriction [GO:0042310] comp53513_c0_seq1,319,58.3072,1.07495554,1,15,,9.00E-12,Q8GRC3,"Alpha,alpha-trehalose phosphorylase (TPase) (EC 2.4.1.64)","Alpha,alpha-trehalose phosphorylase (TPase) (EC 2.4.1.64)",GO:0047656; GO:0030246; GO:0005993,"alpha,alpha-trehalose phosphorylase activity; carbohydrate binding; trehalose catabolic process",PF03633;PF03632;PF03636;,,,,,,,,,TREP_GEOSE,Geobacillus stearothermophilus (Bacillus stearothermophilus),trehalose catabolic process [GO:0005993] comp53651_c0_seq2,320,43.4375,0.41207078,5,0,,,,,,,,,2.00E-44,CHOYP_LOC579391.1.1,,,,,,,,, comp53658_c0_seq1,254,50.7874,1.11843839,2,0,,1.00E-10,Q6TL19,Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G),Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G),GO:0005524; GO:0005525; GO:0009897; GO:0004383; GO:0016021; GO:0035556; GO:0004672,ATP binding; GTP binding; external side of plasma membrane; guanylate cyclase activity; integral to membrane; intracellular signal transduction; protein kinase activity,PF01094;PF00211;PF07714;,5.00E-19,CHOYP_GCY.1.4,,,,,,,GUC2G_MOUSE,Mus musculus (Mouse),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165] comp53658_c1_seq1,236,46.6102,1.02701844,6,0,,7.00E-20,P18910,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0005525; GO:0007166; GO:0042417; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0048662; GO:0017046; GO:0005886; GO:0030828; GO:0004672; GO:0019901; GO:0007168; GO:0050880,ATP binding; GTP binding; cell surface receptor signaling pathway; dopamine metabolic process; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of smooth muscle cell proliferation; peptide hormone binding; plasma membrane; positive regulation of cGMP biosynthetic process; protein kinase activity; protein kinase binding; receptor guanylyl cyclase signaling pathway; regulation of blood vessel size,PF01094;PF00211;PF07714;,7.00E-36,CHOYP_LOC726069.1.1,,,,,,,ANPRA_RAT,Rattus norvegicus (Rat),cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880] comp53664_c0_seq1,270,45.1852,0.6570672,0,3,,2.00E-20,O43451,"Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase)]","Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase)]",GO:0004558; GO:0016160; GO:0016324; GO:0030246; GO:0004339; GO:0016021; GO:0032450; GO:0005886; GO:0044245; GO:0044281; GO:0005983,"alpha-glucosidase activity; amylase activity; apical plasma membrane; carbohydrate binding; glucan 1,4-alpha-glucosidase activity; integral to membrane; maltose alpha-glucosidase activity; plasma membrane; polysaccharide digestion; small molecule metabolic process; starch catabolic process",PF01055;PF16863;PF00088;,,,,,,,,,MGA_HUMAN,Homo sapiens (Human),polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983] comp5369_c0_seq1,288,58.6806,1.34628952,2,6,,1.00E-24,Q73EU1,DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13),DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13),GO:0005524; GO:0004004; GO:0003723; GO:0043590; GO:0005737,ATP binding; ATP-dependent RNA helicase activity; RNA binding; bacterial nucleoid; cytoplasm,PF00270;PF00271;,,,,,,,,,CSHA_BACC1,Bacillus cereus (strain ATCC 10987 / NRS 248),RNA catabolic process [GO:0006401]; RNA secondary structure unwinding [GO:0010501] comp5371_c0_seq1,250,48.4,0.82431532,2,0,,3.00E-09,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp53875_c0_seq1,261,60.5364,1.13512578,1,7,,1.00E-17,Q1B3X9,Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B),Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B),GO:0005524; GO:0016021; GO:0009405; GO:0018106; GO:0004721; GO:0000155; GO:0005886; GO:0006950; GO:0023014,ATP binding; integral to membrane; pathogenesis; peptidyl-histidine phosphorylation; phosphoprotein phosphatase activity; phosphorelay sensor kinase activity; plasma membrane; response to stress; signal transduction by phosphorylation,PF00672;PF02518;PF00512;,,,,,,,,,MPRB_MYCSS,Mycobacterium sp. (strain MCS),pathogenesis [GO:0009405] comp53897_c0_seq1,826,40.9201,0.40904494,26,7,,2.00E-114,Q8BUV8,Protein GPR107,Protein GPR107,GO:0016021,integral to membrane,PF06814;,1.00E-78,CHOYP_SMAG1.1.1,,,,,,,GP107_MOUSE,Mus musculus (Mouse),clathrin-mediated endocytosis [GO:0072583] comp53931_c0_seq1,205,60,1.43750066,0,3,,1.00E-31,Q47BK5,Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS),Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS),GO:0005524; GO:0002161; GO:0005737; GO:0004822; GO:0006428; GO:0006450; GO:0008270,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; isoleucine-tRNA ligase activity; isoleucyl-tRNA aminoacylation; regulation of translational fidelity; zinc ion binding,PF08264;PF00133;PF06827;,,,,,,,,,SYI_DECAR,Dechloromonas aromatica (strain RCB),isoleucyl-tRNA aminoacylation [GO:0006428] comp53975_c1_seq1,452,44.9115,0.31051856,13,24,,2.00E-14,Q2KHT3,Protein CLEC16A,Protein CLEC16A (C-type lectin domain family 16 member A),,,PF09758;,5.00E-29,CHOYP_LOC410511.1.2,,,,,,,CL16A_HUMAN,Homo sapiens (Human),autophagy [GO:0006914] comp53999_c0_seq1,812,39.6552,0.98081562,4,369,,,,,,,,,,,2.00E-14,ruditapes_c8071,,,,,,, comp54097_c0_seq2,245,38.3673,0.44870789,4,0,,6.00E-16,Q9Y5W8,Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1),Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1),GO:0007154; GO:0005769; GO:0031901; GO:0006886; GO:0035091; GO:0043547; GO:0038032,cell communication; early endosome; early endosome membrane; intracellular protein transport; phosphatidylinositol binding; positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway,PF08628;PF00787;PF02194;PF00615;,,,,,,,,,SNX13_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547] comp54153_c0_seq1,387,36.1757,1.18800548,14,0,,,,,,,,,,,1.00E-14,ruditapes_c19609,,,,,,, comp54161_c1_seq1,295,50.5085,0.76826986,14,5,,5.00E-36,O60333,Kinesin-like protein KIF1B (Klp),Kinesin-like protein KIF1B (Klp),GO:0005524; GO:0016887; GO:0008089; GO:0006915; GO:0030659; GO:0019894; GO:0005871; GO:0005874; GO:0005875; GO:0003777; GO:0005739; GO:0047497; GO:0007274; GO:0043005; GO:0007270; GO:0005543,ATP binding; ATPase activity; anterograde axon cargo transport; apoptotic process; cytoplasmic vesicle membrane; kinesin binding; kinesin complex; microtubule; microtubule associated complex; microtubule motor activity; mitochondrion; mitochondrion transport along microtubule; neuromuscular synaptic transmission; neuron projection; neuron-neuron synaptic transmission; phospholipid binding,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,1.00E-20,CHOYP_LOC100875479.1.2,,,,,,,KIF1B_HUMAN,Homo sapiens (Human),anterograde axonal transport [GO:0008089]; apoptotic process [GO:0006915]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270] comp54192_c0_seq1,291,38.8316,0.6589375,6,0,,6.00E-15,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp54228_c0_seq1,268,42.9104,0.57304511,8,10,,2.00E-18,Q5R4L1,Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2),Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2),GO:0005524; GO:0000082; GO:0032486; GO:0005814; GO:0030425; GO:0060292; GO:0060291; GO:0007613; GO:0007093; GO:0007052; GO:0043066; GO:0043123; GO:0004674; GO:0046599; GO:0004871,ATP binding; G1/S transition of mitotic cell cycle; Rap protein signal transduction; centriole; dendrite; long term synaptic depression; long-term synaptic potentiation; memory; mitotic cell cycle checkpoint; mitotic spindle organization; negative regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein serine/threonine kinase activity; regulation of centriole replication; signal transducer activity,PF00069;PF00659;,2.00E-24,CHOYP_LOC584420.1.1,,,,,,,PLK2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),G1/S transition of mitotic cell cycle [GO:0000082]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitotic cell cycle checkpoint [GO:0007093]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of centriole replication [GO:0046599]; regulation of synaptic plasticity [GO:0048167] comp54267_c0_seq1,203,39.4089,0.51033133,18,78,,5.00E-07,O77788,Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein),Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein),GO:0005882; GO:0005198,intermediate filament; structural molecule activity,PF00038;PF04732;,,,,,,,,,NFM_BOVIN,Bos taurus (Bovine),axon development [GO:0061564] comp54277_c0_seq1,578,39.9654,0.88844826,10,10,,3.00E-35,O93470,Matrix metalloproteinase-21 (MMP-21) (xMMP) (EC 3.4.24.-),Matrix metalloproteinase-21 (MMP-21) (xMMP) (EC 3.4.24.-),GO:0005509; GO:0031012; GO:0005576; GO:0004222; GO:0006508; GO:0008270,calcium ion binding; extracellular matrix; extracellular region; metalloendopeptidase activity; proteolysis; zinc ion binding,PF00045;PF00413;PF01471;,3.00E-32,CHOYP_MMP21.1.1,,,,,,,MMP21_XENLA,Xenopus laevis (African clawed frog), comp54304_c0_seq1,210,54.7619,0.32462275,2,19,,2.00E-08,Q9H2J1,Uncharacterized protein C9orf37,Uncharacterized protein ARRDC1-AS1 (ARRDC1 antisense RNA 1) (ARRDC1 antisense gene protein 1),,,,,,,,,,,,CI037_HUMAN,Homo sapiens (Human), comp54329_c0_seq1,615,43.0894,0.80711162,20,10,,2.00E-74,Q0VC91,Suppressor of cytokine signaling 4 (SOCS-4),Suppressor of cytokine signaling 4 (SOCS-4),GO:0035556; GO:0007175; GO:0032436; GO:0016567; GO:0040008,intracellular signal transduction; negative regulation of epidermal growth factor-activated receptor activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; regulation of growth,PF00017;PF12610;PF07525;,6.00E-55,CHOYP_SOCS-5.1.1,,,,,,,SOCS4_BOVIN,Bos taurus (Bovine),cytokine-mediated signaling pathway [GO:0019221]; intracellular signal transduction [GO:0035556]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008] comp54365_c0_seq1,596,41.7785,0.61673727,0,383,,1.00E-21,Q86UP9,Lipoma HMGIC fusion partner-like 3 protein,Lipoma HMGIC fusion partner-like 3 protein,GO:0016021,integral to membrane,PF10242;,9.00E-27,CHOYP_LOC578003.1.1,,,,,,,LHPL3_HUMAN,Homo sapiens (Human), comp54381_c0_seq1,225,50.2222,1.02662638,0,54,,4.00E-11,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp54411_c0_seq1,201,40.796,1.08216964,0,16,,5.00E-15,Q6RY07,Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),Acidic mammalian chitinase (AMCase) (EC 3.2.1.14),GO:0006915; GO:0008061; GO:0006032; GO:0004568; GO:0005737; GO:0005615; GO:0000272; GO:0090197; GO:0002532,apoptotic process; chitin binding; chitin catabolic process; chitinase activity; cytoplasm; extracellular space; polysaccharide catabolic process; positive regulation of chemokine secretion; production of molecular mediator involved in inflammatory response,PF01607;PF00704;,5.00E-11,CHOYP_CHIA.3.3,,,,,,,CHIA_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532] comp54424_c0_seq1,212,35.3774,0.92879974,4,10,,5.00E-06,Q4UMH6,Putative ankyrin repeat protein RF_0381,Putative ankyrin repeat protein RF_0381,GO:0015969,guanosine tetraphosphate metabolic process,PF00023;PF12796;PF04607;,,,,,,,,,Y381_RICFE,Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi),guanosine tetraphosphate metabolic process [GO:0015969] comp54425_c0_seq1,455,41.3187,1.23913642,0,70,,2.00E-14,Q9ES30,Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26),GO:0005581; GO:0005615; GO:0042593; GO:0042802; GO:0045721; GO:0070374; GO:0070165; GO:0050715; GO:0051897; GO:0051259,collagen; extracellular space; glucose homeostasis; identical protein binding; negative regulation of gluconeogenesis; positive regulation of ERK1 and ERK2 cascade; positive regulation of adiponectin secretion; positive regulation of cytokine secretion; positive regulation of protein kinase B signaling cascade; protein oligomerization,PF00386;PF01391;,,,,,,,,,C1QT3_MOUSE,Mus musculus (Mouse),cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206] comp5447_c0_seq1,326,47.8528,0.37679367,8,0,,1.00E-13,Q8N3P4,Vacuolar protein sorting-associated protein 8 homolog,Vacuolar protein sorting-associated protein 8 homolog,GO:0008270,zinc ion binding,PF12816;,5.00E-52,CHOYP_VPS8.1.1,,,,,,,VPS8_HUMAN,Homo sapiens (Human),endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031] comp54520_c0_seq1,254,49.6063,0.26507687,7,14,,1.00E-05,P10074,Zinc finger and BTB domain-containing protein 48 (Krueppel-related zinc finger protein 3) (Protein HKR3) (Zinc finger protein 855),Zinc finger and BTB domain-containing protein 48 (Krueppel-related zinc finger protein 3) (Protein HKR3) (Zinc finger protein 855),GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT48_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp54544_c0_seq1,247,46.1538,0.15342039,3,0,,3.00E-11,P36007,Threo-3-hydroxyaspartate ammonia-lyase (EC 4.3.1.16) (L-threo-3-hydroxyaspartate dehydratase),Threo-3-hydroxyaspartate ammonia-lyase (EC 4.3.1.16) (L-threo-3-hydroxyaspartate dehydratase),GO:0042219; GO:0030170; GO:0030848,cellular modified amino acid catabolic process; pyridoxal phosphate binding; threo-3-hydroxyaspartate ammonia-lyase activity,PF00291;,9.00E-41,CHOYP_DAR1.2.4,,,,,,,SRY1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular amino acid metabolic process [GO:0006520]; cellular modified amino acid catabolic process [GO:0042219] comp54544_c1_seq1,213,45.5399,0.18772344,1,9,,1.00E-16,Q54HH2,Probable serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase),Probable serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase),GO:0005524; GO:0008721; GO:0070179; GO:0003941; GO:0006563; GO:0005737; GO:0000287; GO:0018249; GO:0030170; GO:0030378,ATP binding; D-serine ammonia-lyase activity; D-serine biosynthetic process; L-serine ammonia-lyase activity; L-serine metabolic process; cytoplasm; magnesium ion binding; protein dehydration; pyridoxal phosphate binding; serine racemase activity,PF00291;,,,,,,,,,SRR_DICDI,Dictyostelium discoideum (Slime mold),D-serine biosynthetic process [GO:0070179]; L-serine metabolic process [GO:0006563]; protein dehydration [GO:0018249] comp54594_c0_seq1,1354,33.2349,0.64976359,0,0,,,,,,,,,8.00E-13,CHOYP_contig_046260,,,,,,,,, comp54594_c0_seq3,702,36.4672,0.22106963,0,0,,,,,,,,,4.00E-13,CHOYP_contig_046260,,,,,,,,, comp54602_c0_seq1,237,43.8819,0.84498546,2,1,,1.00E-06,Q8K1C7,Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT14_MOUSE,Mus musculus (Mouse), comp54610_c0_seq1,1074,40.0372,0.46917662,0,0,,3.00E-20,Q2KJ72,Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21),Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21),GO:0019784; GO:0005737; GO:0016578; GO:0046872; GO:0005634; GO:0045893; GO:0003713; GO:0006351; GO:0004221; GO:0006511; GO:0004843,"NEDD8-specific protease activity; cytoplasm; histone deubiquitination; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity",PF00443;,,,,,,,,,UBP21_BOVIN,Bos taurus (Bovine),"histone deubiquitination [GO:0016578]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp54610_c0_seq2,1322,40.7716,0.4955884,8,9,,0,Q5RBQ4,Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46),Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46),GO:0007610; GO:0016579; GO:0032228; GO:0004221; GO:0006511; GO:0004843,"behavior; protein deubiquitination; regulation of synaptic transmission, GABAergic; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity",PF00443;,0,CHOYP_BRAFLDRAFT_63924.1.1,,,,,,,UBP46_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"behavior [GO:0007610]; protein deubiquitination [GO:0016579]; regulation of synaptic transmission, GABAergic [GO:0032228]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp54617_c0_seq1,825,41.5758,0.33880279,9,36,,3.00E-18,Q8BWA5,Kelch-like protein 31 (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL),Kelch-like protein 31 (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL),GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07707;PF00651;PF01344;,,,,,,,,,KLH31_MOUSE,Mus musculus (Mouse),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]" comp54636_c0_seq1,415,42.6506,0.3732398,3,71,,2.00E-24,P41247,Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2),Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2),GO:0016042; GO:0004806,lipid catabolic process; triglyceride lipase activity,PF01734;,,,,,,,,,PLPL4_HUMAN,Homo sapiens (Human),cellular lipid metabolic process [GO:0044255]; lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] comp54676_c0_seq1,209,43.5407,0.30464914,1,3,,2.00E-13,P23786,"Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)","Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)",GO:0004095; GO:0006853; GO:0006635; GO:0005743; GO:0005730,carnitine O-palmitoyltransferase activity; carnitine shuttle; fatty acid beta-oxidation; mitochondrial inner membrane; nucleolus,PF00755;,,,,,,,,,CPT2_HUMAN,Homo sapiens (Human),carnitine shuttle [GO:0006853]; fatty acid beta-oxidation [GO:0006635] comp54676_c1_seq1,305,47.2131,0.65385318,9,2,,7.00E-23,Q9DC50,Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137),Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137),GO:0008458; GO:0006635; GO:0015908; GO:0005739; GO:0005777,carnitine O-octanoyltransferase activity; fatty acid beta-oxidation; fatty acid transport; mitochondrion; peroxisome,PF00755;,,,,,,,,,OCTC_MOUSE,Mus musculus (Mouse),carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243] comp54692_c0_seq1,203,36.4532,0.60715759,26,61,,,,,,,,,,,8.00E-13,ruditapes2_c1288,,,,,,, comp54703_c0_seq1,315,29.5238,0.29313839,13,48,,,,,,,,,,,3.00E-15,ruditapes_c16868,,,,,,, comp54728_c1_seq1,378,46.0317,0.55676138,3,13,,2.00E-16,Q8BX70,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp54775_c0_seq1,240,65.4167,0.84633576,0,9,,3.00E-09,A1B3Z0,LexA repressor (EC 3.4.21.88),LexA repressor (EC 3.4.21.88),GO:0003677; GO:0006281; GO:0006260; GO:0009432; GO:0045892; GO:0006508; GO:0004252; GO:0006351,"DNA binding; DNA repair; DNA replication; SOS response; negative regulation of transcription, DNA-dependent; proteolysis; serine-type endopeptidase activity; transcription, DNA-dependent",PF01726;PF00717;,,,,,,,,,LEXA_PARDP,Paracoccus denitrificans (strain Pd 1222),"DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]" comp54781_c0_seq1,425,43.5294,0.49801538,13,4,,1.00E-14,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp54793_c0_seq1,305,45.5738,0.38170888,7,0,,,,,,,,,5.00E-33,CHOYP_LOC100368365.2.2,,,,,,,,, comp54847_c0_seq1,455,45.0549,0.6683636,14,0,,,,,,,,,,,3.00E-17,ruditapes_c26045,,,,,,, comp54864_c0_seq1,230,35.6522,0.4125078,3,4,,1.00E-08,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp54864_c1_seq1,293,41.9795,0.78359122,5,6,,1.00E-32,Q9GV77,Extracellular matrix protein 3 (FREM2 homolog),Extracellular matrix protein 3 (FREM2 homolog),GO:0005509; GO:0007154; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; cell communication; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF03160;,,,,,,,,,FREM2_LYTVA,Lytechinus variegatus (Green sea urchin) (Variegated urchin),cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp54880_c0_seq1,269,44.6097,0.37667931,5,9,,6.00E-16,Q5E9L7,Vacuolar protein sorting-associated protein 16 homolog,Vacuolar protein sorting-associated protein 16 homolog,GO:0006886; GO:0031902; GO:0005765,intracellular protein transport; late endosome membrane; lysosomal membrane,PF04840;PF04841;,,,,,,,,,VPS16_BOVIN,Bos taurus (Bovine),"endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]; vacuole organization [GO:0007033]" comp54896_c0_seq1,289,41.5225,0.5741019,8,5,,3.00E-35,B1AVY7,Kinesin-like protein KIF16B,Kinesin-like protein KIF16B,GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,1.00E-27,CHOYP_KI16B.2.3,,,,,,,KI16B_MOUSE,Mus musculus (Mouse),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp54919_c0_seq1,371,40.7008,0.73202679,38,255,,3.00E-21,Q9CQW0,ER membrane protein complex subunit 6 (Transmembrane protein 93),ER membrane protein complex subunit 6 (Transmembrane protein 93),GO:0072546,ER membrane protein complex,PF07019;,8.00E-19,CHOYP_LOC100369729.2.3,2.00E-61,ruditapes_c17468,,,,,EMC6_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; protein folding in endoplasmic reticulum [GO:0034975] comp54966_c0_seq1,547,36.5631,0.55471387,48,44,,6.00E-31,Q6XZP4,Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),GO:0009055; GO:0016021; GO:0046872; GO:0005743; GO:0016491; GO:0070469; GO:0022904,electron carrier activity; integral to membrane; metal ion binding; mitochondrial inner membrane; oxidoreductase activity; respiratory chain; respiratory electron transport chain,PF00032;PF00033;,2.00E-34,CHOYP_CYTB.4.6,,,,,,,CYB_DELKE,Deltamys kempi (Kemp's grass mouse),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp54967_c0_seq1,643,40.902,0.74796929,10,75,,3.00E-16,Q5NDF2,"Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)","Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)",GO:0008375; GO:0005783; GO:0005789; GO:0016021; GO:0006493,acetylglucosaminyltransferase activity; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein O-linked glycosylation,PF04577;,,,,,,,,,GTDC2_BOVIN,Bos taurus (Bovine),neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] comp54983_c0_seq1,411,45.4988,0.47129082,10,0,,5.00E-39,Q5T699,Putative uncharacterized protein C6orf183,Putative uncharacterized protein C6orf183,,,PF15082;,7.00E-20,CHOYP_LOC579367.1.1,,,,,,,CF183_HUMAN,Homo sapiens (Human), comp55039_c0_seq1,230,63.913,1.15716473,0,4,,3.00E-10,Q9RZE7,Probable chromosome 2-partitioning protein ParB (Probable chromosome II-partitioning protein ParB),Probable chromosome 2-partitioning protein ParB (Probable chromosome II-partitioning protein ParB),GO:0003677; GO:0007059,DNA binding; chromosome segregation,PF02195;,,,,,,,,,PARB2_DEIRA,Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422),chromosome segregation [GO:0007059] comp55078_c0_seq1,919,39.7171,0.35969967,6,61,,4.00E-32,Q96FB5,Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1),Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1),GO:0016021; GO:0000179; GO:0031167,"integral to membrane; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation",PF13679;,,,,,,,,,RRNAD_HUMAN,Homo sapiens (Human), comp55078_c0_seq2,763,37.2215,0.41811017,0,0,,9.00E-30,Q8BZG5,Protein RRNAD1,Protein RRNAD1,GO:0016021,integral to membrane,PF13679;,,,,,,,,,RRNAD_MOUSE,Mus musculus (Mouse), comp55135_c0_seq1,241,42.7386,0.55168123,0,9,,7.00E-12,Q9UPR3,Protein SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5),Protein SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5),GO:0005829; GO:0010467; GO:0006406; GO:0000184; GO:0005634; GO:0051721; GO:0035303,"cytosol; gene expression; mRNA export from nucleus; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nucleus; protein phosphatase 2A binding; regulation of dephosphorylation",PF10374;PF10373;PF13638;,,,,,,,,,SMG5_HUMAN,Homo sapiens (Human),"mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]; regulation of telomere maintenance via telomerase [GO:0032210]" comp55155_c0_seq1,280,41.0714,0.76637341,7,43,,8.00E-13,Q9NR61,Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4),Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4),GO:0005112; GO:0007220; GO:0061314; GO:0008015; GO:0072554; GO:0001974; GO:0005509; GO:0003209; GO:0044344; GO:0035924; GO:0035912; GO:0016021; GO:0090051; GO:0008285; GO:0000122; GO:0001569; GO:0003344; GO:0005886; GO:0050767; GO:0003222,Notch binding; Notch receptor processing; Notch signaling involved in heart development; blood circulation; blood vessel lumenization; blood vessel remodeling; calcium ion binding; cardiac atrium morphogenesis; cellular response to fibroblast growth factor stimulus; cellular response to vascular endothelial growth factor stimulus; dorsal aorta morphogenesis; integral to membrane; negative regulation of cell migration involved in sprouting angiogenesis; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; pericardium morphogenesis; plasma membrane; regulation of neurogenesis; ventricular trabecula myocardium morphogenesis,PF01414;PF00008;PF12661;PF07657;,,,,,,,,,DLL4_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; blood circulation [GO:0008015]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; cardiac atrium morphogenesis [GO:0003209]; cardiac ventricle morphogenesis [GO:0003208]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; dorsal aorta morphogenesis [GO:0035912]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of gene expression [GO:0010629]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; patterning of blood vessels [GO:0001569]; pericardium morphogenesis [GO:0003344]; positive regulation of gene expression [GO:0010628]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; ventral spinal cord interneuron fate commitment [GO:0060579]; ventricular trabecula myocardium morphogenesis [GO:0003222]; visual perception [GO:0007601] comp55160_c0_seq1,234,40.5983,0.62501141,0,10,,3.00E-21,P59481,VIP36-like protein (Lectin mannose-binding 2-like) (LMAN2-like protein),VIP36-like protein (Lectin mannose-binding 2-like) (LMAN2-like protein),GO:0005794; GO:0000139; GO:0005789; GO:0016021; GO:0046872; GO:0015031,Golgi apparatus; Golgi membrane; endoplasmic reticulum membrane; integral to membrane; metal ion binding; protein transport,PF03388;,6.00E-24,CHOYP_ISCW_ISCW012623.1.1,,,,,,,LMA2L_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp55222_c0_seq1,207,43.4783,0.52632807,2,0,,4.00E-13,Q6CLN2,GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Glycosylphosphatidylinositol-anchor biosynthesis protein 7),GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Glycosylphosphatidylinositol-anchor biosynthesis protein 7),GO:0006506; GO:0005789; GO:0016021; GO:0016740,GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity,PF01663;,,,,,,,,,GPI7_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica),GPI anchor biosynthetic process [GO:0006506] comp55222_c1_seq1,202,36.6337,0.59488637,4,6,,1.00E-24,Q5H8A4,GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G),GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G),GO:0006501; GO:0051267; GO:0005789; GO:0016021; GO:0016254,C-terminal protein lipidation; CP2 mannose-ethanolamine phosphotransferase activity; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane,PF01663;,5.00E-18,CHOYP_PIGG.1.1,,,,,,,PIGG_HUMAN,Homo sapiens (Human),GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] comp55224_c1_seq1,256,54.6875,0.79956776,4,0,,1.00E-07,Q99MQ5,Collagen alpha-1(XXV) chain (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)],Collagen alpha-1(XXV) chain (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)],GO:0001540; GO:0005581; GO:0005615; GO:0008201; GO:0005887,beta-amyloid binding; collagen; extracellular space; heparin binding; integral to plasma membrane,PF01391;,,,,,,,,,COPA1_MOUSE,Mus musculus (Mouse),axonogenesis involved in innervation [GO:0060385] comp55243_c0_seq1,280,25.7143,0.22301872,7,26,,,,,,,,,,,1.00E-11,ruditapes_c15790,,,,,,, comp55304_c0_seq1,279,61.6487,1.26024532,1,10,,5.00E-57,Q6A7K8,1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase),1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase),GO:0030604; GO:0070402; GO:0019288; GO:0046872; GO:0016114,"1-deoxy-D-xylulose-5-phosphate reductoisomerase activity; NADPH binding; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; metal ion binding; terpenoid biosynthetic process",PF08436;PF02670;PF13288;,,,,,,,,,DXR_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]" comp55331_c0_seq1,395,45.0633,0.60366241,15,36,,2.00E-10,O95980,Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein),Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein),GO:0031225; GO:0001955; GO:0007566; GO:0030198; GO:0016020; GO:0008191; GO:0005886; GO:0004867,anchored to membrane; blood vessel maturation; embryo implantation; extracellular matrix organization; membrane; metalloendopeptidase inhibitor activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF07648;,,,,,,,,,RECK_HUMAN,Homo sapiens (Human),blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684] comp55332_c0_seq1,512,35.7422,0.68683319,9,101,,6.00E-45,Q6P3N5,Protein cornichon homolog 4 (CNIH-4) (Cornichon family AMPA receptor auxiliary protein 4),Protein cornichon homolog 4 (CNIH-4) (Cornichon family AMPA receptor auxiliary protein 4),GO:0016021; GO:0035556,integral to membrane; intracellular signal transduction,PF03311;,2.00E-35,CHOYP_LOC657256.1.1,,,,,,,CNIH4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] comp55367_c0_seq1,221,63.8009,1.07248573,0,9,,1.00E-26,P57010,Signal recognition particle receptor FtsY (SRP receptor),Signal recognition particle receptor FtsY (SRP receptor),GO:0005525; GO:0003924; GO:0006614; GO:0005737; GO:0031226,GTP binding; GTPase activity; SRP-dependent cotranslational protein targeting to membrane; cytoplasm; intrinsic to plasma membrane,PF00448;PF02881;,,,,,,,,,FTSY_NEIMA,Neisseria meningitidis serogroup A / serotype 4A (strain Z2491),SRP-dependent cotranslational protein targeting to membrane [GO:0006614] comp55397_c0_seq1,414,49.0338,0.34051481,11,0,,4.00E-43,Q8NBF2,NHL repeat-containing protein 2,NHL repeat-containing protein 2,,,PF01436;PF13905;,7.00E-20,CHOYP_NHLC2.1.1,,,,,,,NHLC2_HUMAN,Homo sapiens (Human), comp55414_c0_seq1,238,60.9244,0.8672804,1,6,,4.00E-10,P37593,Nitrate/nitrite transporter NarU (Nitrite extrusion protein 2) (Nitrite facilitator 2),Nitrate/nitrite transporter NarU (Nitrite extrusion protein 2) (Nitrite facilitator 2),GO:0016021; GO:0042128; GO:0015112; GO:0015113; GO:0005886,integral to membrane; nitrate assimilation; nitrate transmembrane transporter activity; nitrite transmembrane transporter activity; plasma membrane,PF07690;,,,,,,,,,NARU_SALTY,Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720),nitrate assimilation [GO:0042128]; nitrite transport [GO:0015707] comp55451_c0_seq1,598,33.4448,0.4850707,63,384,,,,,,,,,,,2.00E-14,ruditapes_c22302,,,,,,, comp55480_c0_seq2,309,43.0421,0.42120006,3,4,,4.00E-17,Q9WVM3,Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen),Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen),GO:0005680; GO:0051301; GO:0007067; GO:0070979,anaphase-promoting complex; cell division; mitosis; protein K11-linked ubiquitination,PF13181;,,,,,,,,,APC7_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979] comp55487_c0_seq1,829,39.0832,0.76961824,14,145,,7.00E-58,A1L259,2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) (EC 4.1.1.n1) (Parahox neighbor) (Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase),2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) (EC 4.1.1.97) (Parahox neighbor) (Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase),GO:0019428; GO:0016831; GO:0005777; GO:0006144; GO:0019628,allantoin biosynthetic process; carboxy-lyase activity; peroxisome; purine nucleobase metabolic process; urate catabolic process,PF09349;,4.00E-26,CHOYP_BRAFLDRAFT_276474.1.1,,,,,,,URAD_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] comp5550_c0_seq1,270,45.5556,0.21611142,9,0,,3.00E-21,Q8N1W0,Transmembrane protein FLJ37396,,GO:0016021,integral to membrane,,6.00E-25,CHOYP_LOC579367.1.1,,,,,,,YF005_HUMAN,, comp55553_c0_seq1,268,43.6567,1.06293273,7,2,,3.00E-07,P14533,Squidulin (Optic lobe calcium-binding protein) (SCABP),Squidulin (Optic lobe calcium-binding protein) (SCABP),GO:0005509,calcium ion binding,PF13499;,,,,,,,,,CABO_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii), comp55553_c1_seq1,281,39.8577,1.47694178,2,9,,3.00E-16,A9JTH1,Neurocalcin-delta A,Neurocalcin-delta A,GO:0005509,calcium ion binding,PF13499;PF13833;,,,,,,,,,NCLDA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp55596_c1_seq1,203,40.3941,0.62007584,3,2,,6.00E-31,O60658,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)","High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)",GO:0004115; GO:0004114; GO:0006198; GO:0009187; GO:0005829; GO:0035556; GO:0046872; GO:0000156; GO:0006355,"3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; cAMP catabolic process; cyclic nucleotide metabolic process; cytosol; intracellular signal transduction; metal ion binding; phosphorelay response regulator activity; regulation of transcription, DNA-dependent",PF00989;PF00233;,6.00E-42,CHOYP_PDE8B.1.1,,,,,,,PDE8A_HUMAN,Homo sapiens (Human),"cAMP catabolic process [GO:0006198]; cyclic nucleotide metabolic process [GO:0009187]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]" comp55601_c0_seq1,324,40.1235,1.15632031,3,18,,2.00E-20,Q8BRK9,"Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0030246; GO:0016799; GO:0016021; GO:0006013; GO:0015923; GO:0004572; GO:0006486; GO:0008270,"Golgi membrane; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; integral to membrane; mannose metabolic process; mannosidase activity; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; protein glycosylation; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A2_MOUSE,Mus musculus (Mouse),mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517] comp55632_c1_seq1,429,48.0186,1.0136783,4,80,,1.00E-14,P32314,Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor),Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor),GO:0005634; GO:0043565; GO:0003700; GO:0035914; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription, DNA-dependent",PF00250;,1.00E-17,CHOYP_BRAFLDRAFT_114734.8.8,,,,,,,FOXN2_HUMAN,Homo sapiens (Human),"skeletal muscle cell differentiation [GO:0035914]; transcription, DNA-templated [GO:0006351]" comp55666_c0_seq1,205,59.5122,1.1099402,0,17,,3.00E-08,P42176,Nitrate reductase beta chain (EC 1.7.99.4),Nitrate reductase beta chain (EC 1.7.99.4),GO:0051538; GO:0051539; GO:0046872; GO:0042128; GO:0008940; GO:0009325; GO:0005886,"3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; metal ion binding; nitrate assimilation; nitrate reductase activity; nitrate reductase complex; plasma membrane",PF13247;PF14711;,,,,,,,,,NARH_BACSU,Bacillus subtilis (strain 168),anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128] comp55704_c0_seq1,255,52.9412,1.18000059,0,12,,3.00E-10,Q9C4M5,Glyoxylate reductase (EC 1.1.1.26),Glyoxylate reductase (EC 1.1.1.26),GO:0051287; GO:0005737; GO:0047964,NAD binding; cytoplasm; glyoxylate reductase activity,PF00389;PF02826;,,,,,,,,,GYAR_THELI,Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C), comp55704_c1_seq1,276,53.6232,1.17115508,1,8,,6.00E-23,Q54UH8,D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95),D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95),GO:0006564; GO:0051287; GO:0045335; GO:0004617; GO:0009070,L-serine biosynthetic process; NAD binding; phagocytic vesicle; phosphoglycerate dehydrogenase activity; serine family amino acid biosynthetic process,PF00389;PF02826;,,,,,,,,,SERA_DICDI,Dictyostelium discoideum (Slime mold),L-serine biosynthetic process [GO:0006564]; serine family amino acid biosynthetic process [GO:0009070] comp55713_c0_seq1,874,43.9359,0.71401464,36,33,,2.00E-84,B2RVL6,Zinc finger CCHC domain-containing protein 24,Zinc finger CCHC domain-containing protein 24,GO:0003676; GO:0008270,nucleic acid binding; zinc ion binding,PF17180;PF13696;,1.00E-64,CHOYP_LOC100746981.1.1,,,,,,,ZCH24_MOUSE,Mus musculus (Mouse), comp55775_c0_seq1,265,50.1887,0.72513527,0,23,,1.00E-15,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp55779_c0_seq1,1088,39.4301,0.64973317,250,1152,,5.00E-15,Q9VCA8,Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein),Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein),GO:0003723; GO:0019730; GO:0051298; GO:0001751; GO:0005811; GO:0043066; GO:0046427; GO:0007169,RNA binding; antimicrobial humoral response; centrosome duplication; compound eye photoreceptor cell differentiation; lipid particle; negative regulation of apoptotic process; positive regulation of JAK-STAT cascade; transmembrane receptor protein tyrosine kinase signaling pathway,PF12796;PF00013;,,,,,,,,,ANKHM_DROME,Drosophila melanogaster (Fruit fly),antimicrobial humoral response [GO:0019730]; cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; compound eye photoreceptor cell differentiation [GO:0001751]; negative regulation of apoptotic process [GO:0043066]; positive regulation of JAK-STAT cascade [GO:0046427]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp55804_c0_seq1,436,47.9358,0.3205004,15,4,,8.00E-09,Q8VHN7,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1) (Neurepin) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1) (Neurepin) (Very large G-protein coupled receptor 1),GO:0004930; GO:0005509; GO:0016337; GO:0050910; GO:0005576; GO:0060122; GO:0016021; GO:0007218; GO:0005886; GO:0002142; GO:0007601,G-protein coupled receptor activity; calcium ion binding; cell-cell adhesion; detection of mechanical stimulus involved in sensory perception of sound; extracellular region; inner ear receptor stereocilium organization; integral to membrane; neuropeptide signaling pathway; plasma membrane; stereocilia ankle link complex; visual perception,PF00002;PF03160;PF03736;,,,,,,,,,GPR98_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; inner ear development [GO:0048839]; inner ear receptor stereocilium organization [GO:0060122]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein kinase A signaling [GO:0010739]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601] comp55850_c0_seq1,360,41.1111,1.05105625,0,71,,7.00E-14,Q8K2J9,BTB/POZ domain-containing protein 6,BTB/POZ domain-containing protein 6,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD6_MOUSE,Mus musculus (Mouse), comp55855_c0_seq1,370,39.4595,0.20921205,11,4,,,,,,,,,8.00E-19,CHOYP_BRAFLDRAFT_78229.1.1,,,,,,,,, comp5590_c0_seq1,210,41.9048,0.98091067,1,4,,2.00E-11,P20385,Chorion transcription factor Cf2,Chorion transcription factor Cf2,GO:0001077; GO:0007527; GO:0046872; GO:0005634; GO:0032968; GO:0043565,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; adult somatic muscle development; metal ion binding; nucleus; positive regulation of transcription elongation from RNA polymerase II promoter; sequence-specific DNA binding,PF00096;PF13465;,,,,,,,,,CF2_DROME,Drosophila melanogaster (Fruit fly),"adult somatic muscle development [GO:0007527]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of transcription, DNA-templated [GO:0006355]" comp55922_c0_seq1,309,39.8058,0.95465725,2,62,,6.00E-15,Q647I9,"NACHT, LRR and PYD domains-containing protein 5 (Mater protein homolog)","NACHT, LRR and PYD domains-containing protein 5 (Mater protein homolog)",GO:0005524; GO:0005739; GO:0005730; GO:0017111,ATP binding; mitochondrion; nucleolus; nucleoside-triphosphatase activity,PF13516;PF02758;,2.00E-12,CHOYP_NAL14.1.1,,,,,,,NALP5_BOVIN,Bos taurus (Bovine), comp55933_c0_seq1,451,45.4545,0.91498426,207,273,,3.00E-30,Q6DII2,"Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1)","Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1)",GO:0003723; GO:0008380; GO:0006397; GO:0000166; GO:0005634,RNA binding; RNA splicing; mRNA processing; nucleotide binding; nucleus,PF00076;,2.00E-47,CHOYP_ISCW_ISCW014398.3.3,,,,,,,SRSF1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),mRNA processing [GO:0006397]; RNA splicing [GO:0008380] comp55942_c0_seq1,205,46.3415,0.54837152,7,0,,,,,,,,,4.00E-19,CHOYP_LOC579391.1.1,,,,,,,,, comp55953_c0_seq1,361,43.7673,0.46770385,3,26,,7.00E-60,P41233,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0071222; GO:0071300; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0007040; GO:0045121; GO:0002790; GO:0045335; GO:0006911; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lysosome organization; membrane raft; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,4.00E-73,CHOYP_ABCA1.3.3,,,,,,,ABCA1_MOUSE,Mus musculus (Mouse),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp55963_c0_seq2,904,34.292,0.30547272,4,79,,9.00E-06,P19965,SITS-binding protein (SP105),SITS-binding protein (SP105),GO:0005975; GO:0004553; GO:0016021,"carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; integral to membrane",PF01055;,,,,,,,,,SP15_TORCA,Tetronarce californica (Pacific electric ray) (Torpedo californica),carbohydrate metabolic process [GO:0005975] comp55981_c0_seq1,351,46.7236,1.25659208,6,62,,8.00E-26,Q7QH73,Chorion peroxidase (EC 1.11.1.7),Chorion peroxidase (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;,,,,,,,,,PERC_ANOGA,Anopheles gambiae (African malaria mosquito),hydrogen peroxide catabolic process [GO:0042744]; oogenesis [GO:0048477]; response to oxidative stress [GO:0006979] comp55998_c0_seq1,1373,38.7473,0.36900524,126,69,,6.00E-87,Q5QJC4,DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A),DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A),GO:0016787; GO:0005654; GO:0000715,"hydrolase activity; nucleoplasm; nucleotide-excision repair, DNA damage recognition",PF07522;,1.00E-42,CHOYP_DCLRE1A.1.2,,,,,,,DCR1A_CHICK,Gallus gallus (Chicken),"DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protection from non-homologous end joining at telomere [GO:0031848]" comp56002_c0_seq1,261,39.8467,0.3043018,1,7,,3.00E-11,Q4L235,Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (Aminoadipate-semialdehyde dehydrogenase) (Protein NRPS998),Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (Aminoadipate-semialdehyde dehydrogenase) (Protein NRPS998),GO:0005524; GO:0016878; GO:0006631,ATP binding; acid-thiol ligase activity; fatty acid metabolic process,PF00501;PF00550;PF13360;PF13570;,,,,,,,,,ACSF4_HUMAN,Homo sapiens (Human),fatty acid metabolic process [GO:0006631] comp56034_c0_seq1,272,35.2941,0.119791,8,0,,,,,,,,,2.00E-17,CHOYP_LOC100636931.1.8,,,,,,,,, comp56074_c0_seq1,293,44.3686,0.76836248,2,0,,2.00E-27,Q28970,Unconventional myosin-VIIa (Fragment),Unconventional myosin-VIIa (Fragment),GO:0005524; GO:0005938; GO:0003774; GO:0016459; GO:0007605,ATP binding; cell cortex; motor activity; myosin complex; sensory perception of sound,PF00063;,6.00E-25,CHOYP_MYO7A.1.3,,,,,,,MYO7A_PIG,Sus scrofa (Pig),sensory perception of sound [GO:0007605] comp56164_c0_seq1,212,57.5472,1.20341661,0,12,,3.00E-07,Q6A5N2,50S ribosomal protein L9,50S ribosomal protein L9,GO:0019843; GO:0005840; GO:0003735; GO:0006412,rRNA binding; ribosome; structural constituent of ribosome; translation,PF03948;PF01281;,,,,,,,,,RL9_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),translation [GO:0006412] comp56225_c0_seq1,383,37.0757,0.38209216,3,17,,2.00E-21,A6NK53,Zinc finger protein 233,Zinc finger protein 233,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN233_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp56299_c0_seq1,467,52.6767,0.77751553,6,4,,2.00E-26,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp56338_c0_seq1,213,44.6009,0.50377758,0,43,,5.00E-38,P91791,Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase),Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase),GO:0005737; GO:0042277; GO:0003755; GO:0006457; GO:0000413,cytoplasm; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,6.00E-36,CHOYP_LOC101156984.2.2,9.00E-51,ruditapes_lrc31823,,,,,PPIA_HEMPU,Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus),protein folding [GO:0006457] comp5640_c0_seq1,212,35.8491,0.88751975,4,0,,7.00E-09,Q21751,Putative sodium-dependent excitatory amino acid transporter glt-6,Putative sodium-dependent excitatory amino acid transporter glt-6,GO:0016021; GO:0017153,integral to membrane; sodium:dicarboxylate symporter activity,PF00375;,,,,,,,,,EAA6_CAEEL,Caenorhabditis elegans, comp56467_c0_seq1,392,39.7959,0.57080981,14,72,,3.00E-52,Q6P8Y1,Calcyphosin-like protein,Calcyphosin-like protein,GO:0005509; GO:0005737,calcium ion binding; cytoplasm,PF13499;,9.00E-12,CHOYP_CAPSLB.1.1,,,,,,,CAPSL_MOUSE,Mus musculus (Mouse), comp56484_c0_seq1,296,45.6081,0.63432143,3,52,,,,,,,,,8.00E-30,CHOYP_contig_009415,,,,,,,,, comp56519_c0_seq1,352,36.6477,0.67885163,28,5,,,,,,,,,,,4.00E-13,ruditapes_c14887,,,,,,, comp56550_c0_seq1,392,35.4592,0.75287846,0,50,,4.00E-11,P07476,Involucrin,Involucrin,GO:0001533; GO:0005737; GO:0018153; GO:0031424; GO:0030216; GO:0030674; GO:0010224; GO:0005198,"cornified envelope; cytoplasm; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; keratinization; keratinocyte differentiation; protein binding, bridging; response to UV-B; structural molecule activity",PF00904;PF10583;,,,,,,,,,INVO_HUMAN,Homo sapiens (Human),isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; response to UV-B [GO:0010224] comp56573_c0_seq1,515,43.4951,0.556221,16,11,,7.00E-49,Q90YB1,DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4),DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4),GO:0005524; GO:0003677; GO:0003910; GO:0032807; GO:0051103; GO:0033151; GO:0007049; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0046872; GO:0070419; GO:0005654; GO:0006289,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase IV complex; DNA ligation involved in DNA repair; V(D)J recombination; cell cycle; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; metal ion binding; nonhomologous end joining complex; nucleoplasm; nucleotide-excision repair,PF00533;PF04679;PF01068;PF04675;PF11411;,2.00E-40,CHOYP_LIG4.1.1,,,,,,,DNLI4_CHICK,Gallus gallus (Chicken),"cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; nucleotide-excision repair, DNA gap filling [GO:0006297]" comp56577_c0_seq1,239,65.6904,1.36454631,0,5,,3.00E-47,Q6AAD7,"Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)","Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)",GO:0052908; GO:0003723; GO:0005737; GO:0000179; GO:0031167,"16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity; RNA binding; cytoplasm; rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methylation",PF00398;,,,,,,,,,RSMA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp56581_c0_seq1,201,69.1542,1.08784797,0,10,,2.00E-17,Q58283,Uncharacterized ABC transporter ATP-binding protein MJ0873,Uncharacterized ABC transporter ATP-binding protein MJ0873,GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;,,,,,,,,,Y873_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),transport [GO:0006810] comp56611_c0_seq1,385,59.7403,1.19894748,1,6,,2.00E-15,P07071,Anaerobic ribonucleoside-triphosphate reductase (EC 1.17.4.2),Anaerobic ribonucleoside-triphosphate reductase (EC 1.17.4.2),GO:0006260; GO:0046872; GO:0008998,DNA replication; metal ion binding; ribonucleoside-triphosphate reductase activity,PF13597;,,,,,,,,,NRDD_BPT4,Enterobacteria phage T4 (Bacteriophage T4),DNA replication [GO:0006260] comp56620_c0_seq1,223,68.1614,1.05166434,0,3,,4.00E-33,A1WBL5,Protoheme IX farnesyltransferase (EC 2.5.1.-) (Heme B farnesyltransferase) (Heme O synthase),Protoheme IX farnesyltransferase (EC 2.5.1.-) (Heme B farnesyltransferase) (Heme O synthase),GO:0048034; GO:0016021; GO:0005886; GO:0008495,heme O biosynthetic process; integral to membrane; plasma membrane; protoheme IX farnesyltransferase activity,PF01040;,,,,,,,,,COXX_ACISJ,Acidovorax sp. (strain JS42),heme O biosynthetic process [GO:0048034] comp56683_c0_seq1,208,59.1346,0.71956112,4,3,,7.00E-14,Q9F7Y9,CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase),CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase),GO:0003881; GO:0016021; GO:0046488; GO:0008654; GO:0005886,CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; integral to membrane; phosphatidylinositol metabolic process; phospholipid biosynthetic process; plasma membrane,PF01066;,,,,,,,,,PISA_MYCSM,Mycobacterium smegmatis,phosphatidylinositol metabolic process [GO:0046488]; phospholipid biosynthetic process [GO:0008654] comp56749_c0_seq1,353,45.3258,0.99578858,5,8,,2.00E-06,Q07970,Kinesin-1 (Kinesin-like protein A),Kinesin-1 (Kinesin-like protein A),GO:0005524; GO:0009971; GO:0051301; GO:0005874; GO:0007018; GO:0005872; GO:0008569; GO:0007067; GO:0005634; GO:0009524,ATP binding; anastral spindle assembly involved in male meiosis; cell division; microtubule; microtubule-based movement; minus-end kinesin complex; minus-end-directed microtubule motor activity; mitosis; nucleus; phragmoplast,PF00225;,1.00E-15,CHOYP_BRAFLDRAFT_84054.1.2,,,,,,,ATK1_ARATH,Arabidopsis thaliana (Mouse-ear cress),anastral spindle assembly involved in male meiosis [GO:0009971]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067] comp56778_c0_seq1,347,43.5159,0.68017622,10,0,,4.00E-10,Q8HY11,C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299),C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299),GO:0006897; GO:0045087; GO:0016021; GO:0005537; GO:0046872,endocytosis; innate immune response; integral to membrane; mannose binding; metal ion binding,PF00059;,,,,,,,,,CLC4M_HYLSY,Symphalangus syndactylus (Siamang) (Hylobates syndactylus),adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; innate immune response [GO:0045087] comp56807_c0_seq1,1005,38.209,0.36039498,153,1225,,,,,,,,,,,6.00E-144,ruditapes2_c327,,,,,,, comp56807_c0_seq2,992,38.1048,0.39503336,1,137,,6.00E-98,Q9UBQ5,Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28),Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28),GO:0005829; GO:0016282; GO:0033290; GO:0005852; GO:0001731; GO:0005634; GO:0006446; GO:0043022; GO:0003743; GO:0006413,cytosol; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; formation of translation preinitiation complex; nucleus; regulation of translational initiation; ribosome binding; translation initiation factor activity; translational initiation,PF10075;,8.00E-62,CHOYP_EIF3K.1.1,,,,,,,EIF3K_HUMAN,Homo sapiens (Human),formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] comp56808_c0_seq1,1016,38.3858,0.46569742,1494,401,,2.00E-109,Q96AX2,Ras-related protein Rab-37,Ras-related protein Rab-37,GO:0005525; GO:0005793; GO:0015031; GO:0030141; GO:0007264,GTP binding; endoplasmic reticulum-Golgi intermediate compartment; protein transport; secretory granule; small GTPase mediated signal transduction,PF00071;,1.00E-110,CHOYP_RAB37.1.1,5.00E-12,ruditapes_c10335,,,,,RAB37_HUMAN,Homo sapiens (Human),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp56892_c0_seq1,339,42.4779,0.59211042,8,5,,3.00E-15,Q9DGG6,Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9),Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9),GO:0005524; GO:0004016; GO:0016021; GO:0035556; GO:0046872,ATP binding; adenylate cyclase activity; integral to membrane; intracellular signal transduction; metal ion binding,PF00211;,,,,,,,,,ADCY9_CHICK,Gallus gallus (Chicken),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933] comp56995_c0_seq1,240,42.0833,0.49835439,12,0,,1.00E-31,P49327,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0070402; GO:0004313; GO:0004314; GO:0006084; GO:0071353; GO:0005829; GO:0008144; GO:0006112; GO:0047117; GO:0004319; GO:0006633; GO:0006631; GO:0004312; GO:0042587; GO:0035338; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0015939; GO:0005886; GO:0031325; GO:0019432; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; NADPH binding; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; acetyl-CoA metabolic process; cellular response to interleukin-4; cytosol; drug binding; energy reserve metabolic process; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; fatty acid metabolic process; fatty acid synthase activity; glycogen granule; long-chain fatty-acyl-CoA biosynthetic process; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; pantothenate metabolic process; plasma membrane; positive regulation of cellular metabolic process; triglyceride biosynthetic process; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,4.00E-26,CHOYP_FASN.3.4,,,,,,,FAS_HUMAN,Homo sapiens (Human),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]; pantothenate metabolic process [GO:0015939]; positive regulation of cellular metabolic process [GO:0031325] comp57010_c0_seq1,330,44.5455,0.80101257,9,4,,3.00E-20,P16163,Uricase (EC 1.7.3.3) (Urate oxidase),Uricase (EC 1.7.3.3) (Urate oxidase),GO:0019428; GO:0005777; GO:0006144; GO:0019628; GO:0004846,allantoin biosynthetic process; peroxisome; purine nucleobase metabolic process; urate catabolic process; urate oxidase activity,PF01014;,,,,,,,,,URIC_DROME,Drosophila melanogaster (Fruit fly),allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; response to ethanol [GO:0045471]; urate catabolic process [GO:0019628] comp57013_c0_seq1,437,43.2494,0.44502378,15,35,,4.00E-15,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,,,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp57016_c0_seq1,747,39.4913,0.41364129,29,0,,8.00E-31,Q8BTJ4,Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4),Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4),GO:0047710; GO:0007596; GO:0016021; GO:0005886,bis(5'-adenosyl)-triphosphatase activity; blood coagulation; integral to membrane; plasma membrane,PF01663;,,,,,,,,,ENPP4_MOUSE,Mus musculus (Mouse),blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; purine ribonucleoside catabolic process [GO:0046130] comp57045_c0_seq1,220,65.9091,1.02673434,3,0,,4.00E-06,Q91X52,L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase),GO:0042732; GO:0050038; GO:0006739; GO:0016324; GO:0005903; GO:0005881; GO:0006006; GO:0005902; GO:0016655; GO:0051289; GO:0005997,"D-xylose metabolic process; L-xylulose reductase (NADP+) activity; NADP metabolic process; apical plasma membrane; brush border; cytoplasmic microtubule; glucose metabolic process; microvillus; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein homotetramerization; xylulose metabolic process",,,,,,,,,,DCXR_MOUSE,Mus musculus (Mouse),D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997] comp57057_c0_seq1,222,42.3423,0.92918552,0,42,,,,,,,,,,,8.00E-14,ruditapes_c3836,,,,,,, comp57069_c0_seq1,214,39.2523,0.99539211,1,10,,1.00E-11,P50392,Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)],GO:0016023; GO:0004622; GO:0046872; GO:0001541; GO:0004623; GO:0009395,cytoplasmic membrane-bounded vesicle; lysophospholipase activity; metal ion binding; ovarian follicle development; phospholipase A2 activity; phospholipid catabolic process,PF00168;PF01735;,,,,,,,,,PA24A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ovarian follicle development [GO:0001541]; phospholipid catabolic process [GO:0009395]; response to wounding [GO:0009611] comp57091_c0_seq1,486,43.0041,0.22446629,22,3,,2.00E-18,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,,,,,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp57150_c0_seq1,785,38.5987,0.28475728,29,5,,7.00E-10,Q8R179,Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4),Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4),,,PF07707;PF00651;,,,,,,,,,KBTB4_MOUSE,Mus musculus (Mouse), comp57175_c0_seq1,389,46.7866,0.23688203,9,0,,3.00E-26,Q8AVC3,Sugar phosphate exchanger 2 (Solute carrier family 37 member 2),Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2),GO:0008643; GO:0016021; GO:0055085; GO:0005215,carbohydrate transport; integral to membrane; transmembrane transport; transporter activity,PF07690;,2.00E-21,CHOYP_LOC100695416.1.1,,,,,,,SPX2_XENLA,Xenopus laevis (African clawed frog),carbohydrate transport [GO:0008643]; glucose-6-phosphate transport [GO:0015760]; phosphate ion transmembrane transport [GO:0035435] comp57193_c0_seq1,274,59.854,1.315807,0,14,,2.00E-06,O31568,Probable siderophore transport system permease protein YfiZ,Probable siderophore transport system permease protein YfiZ,GO:0016021; GO:0006811; GO:0055072; GO:0005886; GO:0005215,integral to membrane; ion transport; iron ion homeostasis; plasma membrane; transporter activity,PF01032;,,,,,,,,,YFIZ_BACSU,Bacillus subtilis (strain 168),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] comp57204_c0_seq1,202,63.8614,1.24146878,0,0,,4.00E-18,Q9V253,Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase),Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase),GO:0006189; GO:0051539; GO:0004044; GO:0006541; GO:0046872; GO:0009116; GO:0009113,"'de novo' IMP biosynthetic process; 4 iron, 4 sulfur cluster binding; amidophosphoribosyltransferase activity; glutamine metabolic process; metal ion binding; nucleoside metabolic process; purine nucleobase biosynthetic process",PF13537;PF00156;,,,,,,,,,PUR1_PYRAB,Pyrococcus abyssi (strain GE5 / Orsay),'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113] comp57211_c0_seq1,402,47.0149,0.56561754,13,2,,1.00E-51,Q3MIX3,Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-),GO:0016021; GO:0016301; GO:0005739; GO:0004674,integral to membrane; kinase activity; mitochondrion; protein serine/threonine kinase activity,PF03109;,3.00E-69,CHOYP_ADCK5.1.2,,,,,,,ADCK5_HUMAN,Homo sapiens (Human), comp57279_c0_seq1,662,39.426,0.54654532,26,36,,1.00E-06,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp57294_c0_seq1,395,42.0253,0.4641788,15,9,,2.00E-06,Q7ZXX1,Cell adhesion molecule 3 (Immunoglobulin superfamily member 4B) (IgSF4B),Cell adhesion molecule 3 (Immunoglobulin superfamily member 4B) (IgSF4B),GO:0007155; GO:0016021,cell adhesion; integral to membrane,PF08205;PF07679;,,,,,,,,,CADM3_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155] comp57298_c0_seq2,463,40.3888,0.42471594,0,4,,5.00E-41,Q7SY48,HEAT repeat-containing protein 1 (Protein BAP28),HEAT repeat-containing protein 1 (Protein BAP28),GO:0000462; GO:0043066; GO:0005730; GO:0043487; GO:0030529,"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of apoptotic process; nucleolus; regulation of RNA stability; ribonucleoprotein complex",PF08146;PF12397;,,,,,,,,,HEAT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; regulation of RNA stability [GO:0043487]" comp57325_c0_seq1,346,63.0058,1.13915093,0,28,,2.00E-19,P23888,Polysialic acid transport ATP-binding protein KpsT,Polysialic acid transport ATP-binding protein KpsT,GO:0005524; GO:0006200; GO:0016887; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; plasma membrane; transport,PF00005;,,,,,,,,,KPST1_ECOLX,Escherichia coli,transport [GO:0006810] comp57348_c0_seq1,364,40.9341,1.05263952,7,7,,3.00E-17,A4IGL7,Peroxidasin (EC 1.11.1.7),Peroxidasin (EC 1.11.1.7),GO:0005576; GO:0020037; GO:0042744; GO:0046872; GO:0004601,extracellular region; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity,PF03098;PF07679;PF13855;PF00093;,,,,,,,,,PXDN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp57390_c0_seq1,217,61.2903,0.87407517,0,8,,2.00E-12,A1DM65,Probable beta-galactosidase C (EC 3.2.1.23) (Lactase C),Probable beta-galactosidase C (EC 3.2.1.23) (Lactase C),GO:0004565; GO:0005576; GO:0000272,beta-galactosidase activity; extracellular region; polysaccharide catabolic process,PF10435;PF13363;PF13364;PF01301;,,,,,,,,,BGALC_NEOFI,Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus),polysaccharide catabolic process [GO:0000272] comp57401_c1_seq1,311,40.1929,0.63935087,11,2,,2.00E-39,B1AY13,Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP24_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp57401_c2_seq1,257,42.8016,0.76990556,7,0,,,,,,,,,1.00E-39,CHOYP_UBP24.1.1,,,,,,,,, comp57408_c0_seq1,502,37.8486,0.1727342,13,0,,1.00E-05,Q8K2I2,Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein),Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein),GO:0030154; GO:0005814; GO:0007275; GO:0005634; GO:0006611,cell differentiation; centriole; multicellular organismal development; nucleus; protein export from nucleus,PF07111;,,,,,,,,,CCHCR_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein export from nucleus [GO:0006611] comp57419_c1_seq1,767,46.2842,1.02615177,6,92,,4.00E-66,O01393,Innexin unc-9 (Uncoordinated protein 9),Innexin unc-9 (Uncoordinated protein 9),GO:0005921; GO:0055077; GO:0016021; GO:0034220; GO:0005886,gap junction; gap junction hemi-channel activity; integral to membrane; ion transmembrane transport; plasma membrane,PF00876;,6.00E-94,CHOYP_LOC100533355.1.2,1.00E-12,ruditapes_c18123,,,,,UNC9_CAEEL,Caenorhabditis elegans,ion transmembrane transport [GO:0034220] comp57471_c0_seq1,281,41.637,1.26270256,7,8,,5.00E-06,Q9UPN9,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0030514; GO:0000122; GO:0005654; GO:0017015; GO:0006367; GO:0007179; GO:0004842; GO:0008270,DNA binding; negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; regulation of transforming growth factor beta receptor signaling pathway; transcription initiation from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF00439;PF00628;PF00643;PF13445;,,,,,,,,,TRI33_HUMAN,Homo sapiens (Human),"negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]" comp57490_c1_seq1,227,46.696,0.61080405,5,9,,4.00E-19,Q01082,"Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)","Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)",GO:0043001; GO:0031430; GO:0007184; GO:0003779; GO:0051693; GO:0030506; GO:0030673; GO:0007411; GO:0007182; GO:0032437; GO:0005829; GO:0071709; GO:0000281; GO:0005730; GO:0005543; GO:0072661; GO:0008091; GO:0014731; GO:0005200,Golgi to plasma membrane protein transport; M band; SMAD protein import into nucleus; actin binding; actin filament capping; ankyrin binding; axolemma; axon guidance; common-partner SMAD protein phosphorylation; cuticular plate; cytosol; membrane assembly; mitotic cytokinesis; nucleolus; phospholipid binding; protein targeting to plasma membrane; spectrin; spectrin-associated cytoskeleton; structural constituent of cytoskeleton,PF00307;PF00435;,3.00E-15,CHOYP_LOC100377364.1.2,,,,,,,SPTB2_HUMAN,Homo sapiens (Human),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184] comp57527_c0_seq1,243,64.6091,0.87200957,0,6,,1.00E-08,O30446,UPF0065 protein BP0148 (ORF5),UPF0065 protein BP0148 (ORF5),GO:0030288,outer membrane-bounded periplasmic space,PF03401;,,,,,,,,,Y148_BORPE,Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251), comp57552_c0_seq1,206,69.4175,0.8656118,2,0,,4.00E-16,Q9HZQ3,"Aerobic cobaltochelatase subunit CobN (EC 6.6.1.2) (Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobN)","Aerobic cobaltochelatase subunit CobN (EC 6.6.1.2) (Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobN)",GO:0005524; GO:0009236; GO:0051116; GO:0051188; GO:0005737; GO:0006779,ATP binding; cobalamin biosynthetic process; cobaltochelatase activity; cofactor biosynthetic process; cytoplasm; porphyrin-containing compound biosynthetic process,PF02514;,,,,,,,,,COBN_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779] comp57596_c0_seq1,827,34.8247,0.36111702,27,84,,1.00E-11,Q80WT5,Aftiphilin,Aftiphilin,GO:0005737; GO:0015031,cytoplasm; protein transport,PF15045;,,,,,,,,,AFTIN_MOUSE,Mus musculus (Mouse),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp57662_c0_seq1,320,55.625,0.69032932,5,3,,2.00E-08,P0AAE0,D-serine/D-alanine/glycine transporter,D-serine/D-alanine/glycine transporter,GO:0042944; GO:0042945; GO:0015180; GO:0042895; GO:0001761; GO:0015187; GO:0016021; GO:0005886,D-alanine transmembrane transporter activity; D-serine transmembrane transporter activity; L-alanine transmembrane transporter activity; antibiotic transporter activity; beta-alanine transmembrane transporter activity; glycine transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,CYCA_ECOLI,Escherichia coli (strain K12),antibiotic transport [GO:0042891]; beta-alanine transport [GO:0001762]; D-alanine transport [GO:0042941]; D-serine transport [GO:0042942]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808] comp57697_c1_seq1,277,40.0722,0.36245583,5,0,,2.00E-25,Q91ZX7,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0005887; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0048471; GO:0010875; GO:0006898; GO:0032956; GO:0032429,aorta morphogenesis; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; integral to plasma membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; perinuclear region of cytoplasm; positive regulation of cholesterol efflux; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429] comp57699_c0_seq1,205,43.4146,0.21593805,5,0,,4.00E-24,O95164,Ubiquitin-like protein 3 (Membrane-anchored ubiquitin-fold protein) (HsMUB) (MUB) (Protein HCG-1),Ubiquitin-like protein 3 (Membrane-anchored ubiquitin-fold protein) (HsMUB) (MUB) (Protein HCG-1),GO:0005622; GO:0005886,intracellular; plasma membrane,,6.00E-23,CHOYP_UBL3.1.1,,,,,,,UBL3_HUMAN,Homo sapiens (Human), comp57711_c0_seq1,264,39.7727,0.8660255,5,0,,1.00E-10,Q91YE3,Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20),Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20),GO:0031418; GO:0055008; GO:0005737; GO:0060347; GO:0005506; GO:0060711; GO:0043433; GO:0005634; GO:0032364; GO:0031545; GO:0018401; GO:0045765; GO:0001666; GO:0071731; GO:0060412,L-ascorbic acid binding; cardiac muscle tissue morphogenesis; cytoplasm; heart trabecula formation; iron ion binding; labyrinthine layer development; negative regulation of sequence-specific DNA binding transcription factor activity; nucleus; oxygen homeostasis; peptidyl-proline 4-dioxygenase activity; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; regulation of angiogenesis; response to hypoxia; response to nitric oxide; ventricular septum morphogenesis,PF13640;PF01753;,,,,,,,,,EGLN1_MOUSE,Mus musculus (Mouse),cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of neuron death [GO:1901214]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412] comp57713_c0_seq1,255,60.3922,1.17552828,2,7,,1.00E-51,Q6A8J7,Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS),Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS),GO:0005524; GO:0005737; GO:0004821; GO:0006427,ATP binding; cytoplasm; histidine-tRNA ligase activity; histidyl-tRNA aminoacylation,PF03129;,,,,,,,,,SYH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),histidyl-tRNA aminoacylation [GO:0006427] comp57723_c1_seq1,269,66.5428,1.21380299,1,5,,2.00E-09,P29853,Beta-galactosidase (EC 3.2.1.23) (Lactase-N) (Lactase) (Tilactase),Beta-galactosidase (EC 3.2.1.23) (Lactase-N) (Lactase) (Tilactase),GO:0004565; GO:0005975,beta-galactosidase activity; carbohydrate metabolic process,PF10435;PF13363;PF13364;PF01301;,,,,,,,,,BGAL_ASPNG,Aspergillus niger,carbohydrate metabolic process [GO:0005975] comp57728_c0_seq1,308,39.6104,0.59147465,9,0,,5.00E-15,O14917,Protocadherin-17 (Protocadherin-68),Protocadherin-17 (Protocadherin-68),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;,,,,,,,,,PCD17_HUMAN,Homo sapiens (Human),adult behavior [GO:0030534]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of synaptic transmission [GO:0050805]; presynaptic active zone assembly [GO:1904071]; regulation of synaptic vesicle clustering [GO:2000807] comp57777_c0_seq1,212,70.7547,1.29324306,0,11,,7.00E-12,P76594,Uncharacterized protein YfiQ,Protein lysine acetyltransferase Pka (EC 2.3.1.-),GO:0005524; GO:0048037; GO:0018393; GO:0004468; GO:0046872; GO:0052858; GO:0009408; GO:0006979,ATP binding; cofactor binding; internal peptidyl-lysine acetylation; lysine N-acetyltransferase activity; metal ion binding; peptidyl-lysine N-acetyltransferase activity; response to heat; response to oxidative stress,PF00583;PF13380;PF13607;,,,,,,,,,YFIQ_ECOLI,Escherichia coli (strain K12),internal peptidyl-lysine acetylation [GO:0018393]; protein homotetramerization [GO:0051289]; regulation of protein homooligomerization [GO:0032462]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979] comp57782_c0_seq1,625,42.24,0.79154177,9,89,,9.00E-39,Q6QHF9,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase),Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase),GO:0052899; GO:0052904; GO:0052903; GO:0005782; GO:0006598; GO:0046592; GO:1901307; GO:0009446; GO:0009447; GO:0044281; GO:0046203; GO:0052902; GO:0046208; GO:0052901; GO:0006805,"N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; peroxisomal matrix; polyamine catabolic process; polyamine oxidase activity; positive regulation of spermidine biosynthetic process; putrescine biosynthetic process; putrescine catabolic process; small molecule metabolic process; spermidine catabolic process; spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity; spermine catabolic process; spermine:oxygen oxidoreductase (spermidine-forming) activity; xenobiotic metabolic process",PF01593;,,,,,,,,,PAOX_HUMAN,Homo sapiens (Human),polyamine biosynthetic process [GO:0006596]; polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208] comp5785_c0_seq1,221,40.724,1.11616162,5,0,,2.00E-13,O00602,Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin),Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin),GO:0003823; GO:0005509; GO:0030246; GO:0005581; GO:0001867; GO:0005576; GO:0008228,"antigen binding; calcium ion binding; carbohydrate binding; collagen; complement activation, lectin pathway; extracellular region; opsonization",PF01391;PF00147;,,,,,,,,,FCN1_HUMAN,Homo sapiens (Human),"cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]" comp5787_c0_seq1,228,41.6667,0.52863436,2,5,,3.00E-06,Q8BHW9,Schlafen-like protein 1,Schlafen-like protein 1,GO:0005524,ATP binding,PF04326;,,,,,,,,,SLNL1_MOUSE,Mus musculus (Mouse), comp57914_c0_seq1,273,50.1832,0.17792447,4,6,,1.00E-26,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,3.00E-28,CHOYP_LOC580791.1.1,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp57915_c0_seq1,232,34.4828,0.87431268,10,0,,2.00E-16,Q9P2N4,A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-),GO:0005615; GO:0006516; GO:0004222; GO:0008237; GO:0007275; GO:0045636; GO:0005578; GO:0006508; GO:0008270,extracellular space; glycoprotein catabolic process; metalloendopeptidase activity; metallopeptidase activity; multicellular organismal development; positive regulation of melanocyte differentiation; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF08685;PF01562;PF01421;PF00090;,,,,,,,,,ATS9_HUMAN,Homo sapiens (Human),glycoprotein catabolic process [GO:0006516]; multicellular organism development [GO:0007275]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; vesicle-mediated transport [GO:0016192] comp57963_c0_seq1,225,42.6667,0.39390756,1,9,,7.00E-09,O35099,Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),GO:0005524; GO:0007254; GO:0004709; GO:0000187; GO:0070301; GO:0008656; GO:0005783; GO:0045087; GO:0008631; GO:0000287; GO:0043065; GO:0042803,ATP binding; JNK cascade; MAP kinase kinase kinase activity; activation of MAPK activity; cellular response to hydrogen peroxide; cysteine-type endopeptidase activator activity involved in apoptotic process; endoplasmic reticulum; innate immune response; intrinsic apoptotic signaling pathway in response to oxidative stress; magnesium ion binding; positive regulation of apoptotic process; protein homodimerization activity,PF13281;PF00069;,,,,,,,,,M3K5_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931] comp58030_c1_seq1,336,42.5595,0.86925373,8,2,,2.00E-15,Q91Z46,Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48),Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48),GO:0017017; GO:0005829; GO:0006470; GO:0004725,MAP kinase tyrosine/serine/threonine phosphatase activity; cytosol; protein dephosphorylation; protein tyrosine phosphatase activity,PF00782;PF00581;,,,,,,,,,DUS7_MOUSE,Mus musculus (Mouse),negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335] comp58033_c0_seq1,336,46.7262,0.6569259,10,0,,7.00E-27,Q6VNB8,"WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)","WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)",GO:0005545; GO:0005776; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; autophagic vacuole; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,,,,,,,,,WDFY3_MOUSE,Mus musculus (Mouse),aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239] comp58037_c0_seq1,238,42.437,0.47234035,3,4,,3.00E-29,Q9NRM2,Zinc finger protein 277 (Nuclear receptor-interacting factor 4),Zinc finger protein 277 (Nuclear receptor-interacting factor 4),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF12756;,3.00E-22,CHOYP_LOC100702329.1.1,,,,,,,ZN277_HUMAN,Homo sapiens (Human),"cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp58059_c0_seq1,471,41.4013,0.29854657,1,131,,5.00E-53,O14972,Down syndrome critical region protein 3 (Down syndrome critical region protein A),Down syndrome critical region protein 3 (Down syndrome critical region protein A),GO:0005634; GO:0030904; GO:0007034,nucleus; retromer complex; vacuolar transport,PF03643;,2.00E-65,CHOYP_LOC100640206.1.1,7.00E-25,ruditapes_c16788,,,,,DSCR3_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886] comp5810_c0_seq1,234,42.3077,0.58555887,3,3,,2.00E-38,Q1HKZ5,Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25),Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25),GO:0005524; GO:0008385; GO:0007254; GO:0004709; GO:0016020; GO:0046872; GO:0051092; GO:0046777,ATP binding; IkappaB kinase complex; JNK cascade; MAP kinase kinase kinase activity; membrane; metal ion binding; positive regulation of NF-kappaB transcription factor activity; protein autophosphorylation,PF07714;,2.00E-36,CHOYP_LOC590385.1.1,,,,,,,M3K13_MOUSE,Mus musculus (Mouse),activation of MAPKK activity [GO:0000186]; JNK cascade [GO:0007254]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp5819_c0_seq1,364,45.8791,0.47198632,12,0,,1.00E-29,Q8NEN9,PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104),PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104),GO:0007010; GO:0035556; GO:0046872; GO:0019048; GO:0022604,cytoskeleton organization; intracellular signal transduction; metal ion binding; modulation by virus of host morphology or physiology; regulation of cell morphogenesis,PF00130;PF00595;,,,,,,,,,PDZD8_HUMAN,Homo sapiens (Human),cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; regulation of cell morphogenesis [GO:0022604]; viral process [GO:0016032] comp58205_c0_seq1,427,48.2436,0.24205996,11,33,,4.00E-07,Q8BXJ2,Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132),Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132),GO:0003677; GO:0003682; GO:0046872; GO:0005634; GO:0045893; GO:0003700; GO:0006351,"DNA binding; chromatin binding; metal ion binding; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01448;PF13912;,6.00E-15,CHOYP_LOC100889942.1.1,,,,,,,TREF1_MOUSE,Mus musculus (Mouse),"positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp58221_c0_seq1,236,39.4068,0.54963881,2,0,,5.00E-11,Q59E55,NGFI-A-binding protein homolog (dNAB),NGFI-A-binding protein homolog (dNAB),GO:0008283; GO:0007626; GO:0045892; GO:0014019; GO:0048666; GO:0005634; GO:0003712; GO:0006351; GO:0035222,"cell proliferation; locomotory behavior; negative regulation of transcription, DNA-dependent; neuroblast development; neuron development; nucleus; transcription cofactor activity; transcription, DNA-dependent; wing disc pattern formation",PF04904;PF04905;,,,,,,,,,NAB_DROME,Drosophila melanogaster (Fruit fly),"cell proliferation [GO:0008283]; locomotory behavior [GO:0007626]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroblast development [GO:0014019]; neuron development [GO:0048666]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]" comp58233_c0_seq1,425,51.0588,1.02281479,9,6,,1.00E-17,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,,,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp58265_c0_seq1,457,44.4201,0.84518664,6,14,,1.00E-10,O60494,Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),GO:0005794; GO:0016324; GO:0031526; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0009235; GO:0015889; GO:0005829; GO:0030139; GO:0005783; GO:0010008; GO:0031232; GO:0042157; GO:0042953; GO:0043202; GO:0005765; GO:0042803; GO:0004872; GO:0006898; GO:0001894; GO:0005215; GO:0042359,Golgi apparatus; apical plasma membrane; brush border membrane; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; cobalamin metabolic process; cobalamin transport; cytosol; endocytic vesicle; endoplasmic reticulum; endosome membrane; extrinsic to external side of plasma membrane; lipoprotein metabolic process; lipoprotein transport; lysosomal lumen; lysosomal membrane; protein homodimerization activity; receptor activity; receptor-mediated endocytosis; tissue homeostasis; transporter activity; vitamin D metabolic process,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_HUMAN,Homo sapiens (Human),cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359] comp58272_c0_seq1,901,41.9534,0.53081192,36,32,,4.00E-30,P57071,PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298),PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRD15_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp58298_c0_seq1,234,64.1026,1.1280206,0,14,,8.00E-11,Q9K0I2,"Phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase)","Phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase)",GO:0005524; GO:0006094; GO:0046872; GO:0006090; GO:0008986,"ATP binding; gluconeogenesis; metal ion binding; pyruvate metabolic process; pyruvate, water dikinase activity",PF00391;PF02896;PF01326;,,,,,,,,,PPSA_NEIMB,Neisseria meningitidis serogroup B (strain MC58),gluconeogenesis [GO:0006094]; pyruvate metabolic process [GO:0006090] comp58358_c0_seq1,759,40.7115,0.86371336,22,21,,1.00E-95,Q16975,Calcium-independent protein kinase C (EC 2.7.11.13) (APL II),Calcium-independent protein kinase C (EC 2.7.11.13) (APL II),GO:0005524; GO:0035556; GO:0016020; GO:0046872; GO:0004697,ATP binding; intracellular signal transduction; membrane; metal ion binding; protein kinase C activity,PF00130;PF00168;PF00069;PF00433;,8.00E-105,CHOYP_KPC2.3.3,,,,,,,KPC2_APLCA,Aplysia californica (California sea hare),intracellular signal transduction [GO:0035556] comp58369_c1_seq1,218,48.6239,0.57524663,1,3,,2.00E-11,Q69ZJ7,Protein RIC1 homolog,RAB6A-GEF complex partner protein 1 (Protein RIC1 homolog),GO:0016021,integral to membrane,PF07064;,,,,,,,,,RIC1_MOUSE,Mus musculus (Mouse),"negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]" comp58374_c1_seq1,214,40.6542,1.02383188,4,2,,,,,,,,,1.00E-25,CHOYP_contig_055381,,,,,,,,, comp58419_c0_seq1,788,40.8629,0.70182269,21,34,,1.00E-19,Q60674,Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta),GO:0003677; GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0004887; GO:0008270,DNA binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,NR1D2_MOUSE,Mus musculus (Mouse),"lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]" comp58422_c0_seq1,274,43.7956,0.7333431,8,6,,1.00E-36,Q5ZKJ0,Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein),Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein),GO:0006915; GO:0016021,apoptotic process; integral to membrane,PF05602;,1.00E-13,CHOYP_BRAFLDRAFT_238322.1.1,,,,,,,CLP1L_CHICK,Gallus gallus (Chicken),apoptotic process [GO:0006915] comp58424_c0_seq1,355,43.662,0.65201983,1,7,,4.00E-43,Q3S8M4,Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very-long-chain 3-oxoacyl-CoA synthase 4),Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4),GO:0019367; GO:0030176; GO:0016740; GO:0042761,"fatty acid elongation, saturated fatty acid; integral to endoplasmic reticulum membrane; transferase activity; very long-chain fatty acid biosynthetic process",PF01151;,9.00E-56,CHOYP_ZGC_112263.2.2,,,,,,,ELOV4_MACMU,Macaca mulatta (Rhesus macaque),"fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]" comp58450_c0_seq1,202,68.8119,1.18173374,3,0,,2.00E-14,Q48GY7,Putative ribose/galactose/methyl galactoside import ATP-binding protein (EC 3.6.3.17),Putative ribose/galactose/methyl galactoside import ATP-binding protein (EC 3.6.3.17),GO:0005524; GO:0006200; GO:0015407; GO:0005886,ATP binding; ATP catabolic process; monosaccharide-transporting ATPase activity; plasma membrane,PF00005;,,,,,,,,,RGMG_PSE14,Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) (Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)), comp58468_c0_seq1,668,47.1557,0.74071354,16,7,,2.00E-70,Q9ULL1,Pleckstrin homology domain-containing family G member 1,Pleckstrin homology domain-containing family G member 1,GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,,,,,,,,,PKHG1_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp58511_c0_seq1,284,48.2394,0.49351261,7,9,,1.00E-18,P18737,Gastrula zinc finger protein XlCGF8.2DB (Fragment),Gastrula zinc finger protein XlCGF8.2DB (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZG8_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp58565_c0_seq1,398,42.7136,0.44235313,10,25,,1.00E-13,Q8TBB1,E3 ubiquitin-protein ligase LNX (EC 6.3.2.-) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2),E3 ubiquitin-protein ligase LNX (EC 6.3.2.-) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2),GO:0005737; GO:0051260; GO:0042787; GO:0004842; GO:0008270,cytoplasm; protein homooligomerization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF00595;PF00097;,1.00E-17,CHOYP_LNX2.1.1,,,,,,,LNX1_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp58588_c0_seq1,648,34.7222,0.56902734,7,30,,,,,,,,,,,4.00E-23,ruditapes_c31713,,,,,,, comp58594_c0_seq1,443,63.8826,1.07734853,1,18,,2.00E-37,O29781,2-oxoglutarate synthase subunit KorA (EC 1.2.7.3) (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit alpha),2-oxoglutarate synthase subunit KorA (EC 1.2.7.3) (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit alpha),GO:0047553,2-oxoglutarate synthase activity,PF17147;PF01855;,,,,,,,,,KORA_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126), comp58608_c0_seq1,354,46.6102,0.47235741,14,37,,2.00E-12,Q6RG02,Vitellogenin [Cleaved into: Vitellin],Vitellogenin [Cleaved into: Vitellin],GO:0008289; GO:0005319; GO:0045735; GO:0048477,lipid binding; lipid transporter activity; nutrient reservoir activity; oogenesis,PF06448;PF09172;PF01347;PF00094;,,,,,,,,,VIT_FENME,Fenneropenaeus merguiensis (Banana prawn) (Penaeus merguiensis),oogenesis [GO:0048477] comp58635_c0_seq1,511,38.9432,0.31206946,15,20,,,,,,,,,4.00E-11,CHOYP_LOC100485694.2.2,,,,,,,,, comp58637_c0_seq1,729,43.8957,0.65957069,15,69,,7.00E-42,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,1.00E-19,CHOYP_LOC100704608.1.1,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp58643_c0_seq1,693,37.518,0.9156241,22,7,,1.00E-15,Q8TF44,C2 calcium-dependent domain-containing protein 4C (Nuclear-localized factor 3) (Protein FAM148C),C2 calcium-dependent domain-containing protein 4C (Nuclear-localized factor 3) (Protein FAM148C),,,PF00168;,2.00E-17,CHOYP_LOC100371008.1.1,,,,,,,C2C4C_HUMAN,Homo sapiens (Human), comp58671_c0_seq1,358,35.7542,0.5279453,16,19,,7.00E-30,Q5ZKJ5,Transmembrane protein 180,Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A),GO:0016021,integral to membrane,,,,,,,,,,TM180_CHICK,Gallus gallus (Chicken), comp58691_c0_seq1,328,43.2927,0.32736623,9,15,,1.00E-22,P69527,Aminopeptidase O (AP-O) (EC 3.4.11.-),Aminopeptidase O (AP-O) (EC 3.4.11.-),GO:0004177; GO:0005737; GO:0019370; GO:0008237; GO:0006508; GO:0008270,aminopeptidase activity; cytoplasm; leukotriene biosynthetic process; metallopeptidase activity; proteolysis; zinc ion binding,PF09127;PF01433;,6.00E-13,CHOYP_AMPO.1.1,,,,,,,AMPO_RAT,Rattus norvegicus (Rat),peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp58694_c0_seq1,597,43.8861,0.46495346,27,35,,4.00E-10,Q6GR00,SUZ domain-containing protein 1,SUZ domain-containing protein 1,,,PF12752;PF12901;,,,,,,,,,SZRD1_XENLA,Xenopus laevis (African clawed frog), comp58714_c0_seq1,275,42.5455,1.14796527,4,7,,3.00E-11,O08746,Matrilin-2,Matrilin-2,GO:0007411; GO:0005604; GO:0005509; GO:0031104; GO:0008347; GO:0001764; GO:0048678,axon guidance; basement membrane; calcium ion binding; dendrite regeneration; glial cell migration; neuron migration; response to axon injury,PF07645;PF10393;PF00092;,,,,,,,,,MATN2_MOUSE,Mus musculus (Mouse),axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; response to axon injury [GO:0048678] comp58719_c0_seq1,221,41.629,0.31490006,2,0,,3.00E-19,P84060,Dystrobrevin beta (DTN-B) (Beta-dystrobrevin),Dystrobrevin beta (DTN-B) (Beta-dystrobrevin),GO:0005509; GO:0005737; GO:0008270,calcium ion binding; cytoplasm; zinc ion binding,PF09068;PF09069;PF00569;,,,,,,,,,DTNB_RAT,Rattus norvegicus (Rat), comp58747_c0_seq1,324,47.5309,0.36111455,4,8,,5.00E-24,Q9STT5,ABC transporter A family member 7 (ABC transporter ABCA.7) (AtABCA7) (Probable ABC2 homolog 6),ABC transporter A family member 7 (ABC transporter ABCA.7) (AtABCA7) (Probable ABC2 homolog 6),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0005886; GO:0009506; GO:0005215,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; plasma membrane; plasmodesma; transporter activity,PF00005;,,,,,,,,,AB7A_ARATH,Arabidopsis thaliana (Mouse-ear cress),lipid transport [GO:0006869] comp58755_c0_seq1,365,43.0137,1.09691133,4,27,,2.00E-20,Q99L04,Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-),GO:0005783; GO:0005743; GO:0016491,endoplasmic reticulum; mitochondrial inner membrane; oxidoreductase activity,PF00106;,,,,,,,,,DHRS1_MOUSE,Mus musculus (Mouse), comp58780_c0_seq1,655,39.084,0.56274641,4,31,,2.00E-08,O43734,Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2),Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2),GO:0001783; GO:0006959; GO:0048305; GO:0035556; GO:0043123,B cell apoptotic process; humoral immune response; immunoglobulin secretion; intracellular signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade,PF08357;,,,,,,,,,CIKS_HUMAN,Homo sapiens (Human),B cell apoptotic process [GO:0001783]; humoral immune response [GO:0006959]; immunoglobulin secretion [GO:0048305]; intracellular signal transduction [GO:0035556]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp58847_c0_seq1,366,31.9672,1.08196562,7,0,,7.00E-07,Q8Z4N2,Chaperone protein HscA (Hsc66),Chaperone protein HscA (Hsc66),GO:0005524; GO:0016887; GO:0016226; GO:0006457,ATP binding; ATPase activity; iron-sulfur cluster assembly; protein folding,PF00012;,,,,,,,,,HSCA_SALTI,Salmonella typhi,iron-sulfur cluster assembly [GO:0016226]; protein folding [GO:0006457] comp58882_c0_seq1,286,40.9091,0.3515046,0,30,,2.00E-16,Q54FB7,Xanthine dehydrogenase (XD) (EC 1.17.1.4),Xanthine dehydrogenase (XD) (EC 1.17.1.4),GO:0051537; GO:0008762; GO:0009055; GO:0050660; GO:0005506; GO:0043546; GO:0005777; GO:0009115; GO:0004854,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdopterin cofactor binding; peroxisome; xanthine catabolic process; xanthine dehydrogenase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_DICDI,Dictyostelium discoideum (Slime mold),xanthine catabolic process [GO:0009115] comp58888_c0_seq1,434,41.9355,0.31985464,21,8,,7.00E-10,P22897,Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206),GO:0010008; GO:0005887; GO:0005537; GO:0004872; GO:0006898,endosome membrane; integral to plasma membrane; mannose binding; receptor activity; receptor-mediated endocytosis,PF00040;PF00059;PF00652;,,,,,,,,,MRC1_HUMAN,Homo sapiens (Human),cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898] comp58913_c0_seq1,410,41.7073,0.45239675,19,17,,1.00E-27,Q1LU86,Protein FAM92A1,Protein FAM92A1,,,PF06730;,3.00E-18,CHOYP_BRAFLDRAFT_57402.3.3,,,,,,,F92A1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp58918_c0_seq1,375,47.2,0.91239474,5,21,,2.00E-13,A1XQX0,Neurexin-1a (Neurexin Ia-alpha) (Neurexin-1a-alpha),Neurexin-1a (Neurexin Ia-alpha) (Neurexin-1a-alpha),GO:0007155; GO:0016021; GO:0046872; GO:0007269; GO:0051965; GO:0090129; GO:0007416,cell adhesion; integral to membrane; metal ion binding; neurotransmitter secretion; positive regulation of synapse assembly; positive regulation of synapse maturation; synapse assembly,PF00008;PF02210;PF01034;,,,,,,,,,NR1AA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; sprouting angiogenesis [GO:0002040] comp58930_c0_seq1,284,42.2535,0.48593953,14,10,,2.00E-34,Q5E9N9,DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2),DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2),GO:0003677; GO:0006310; GO:0006281; GO:0003906; GO:0007049; GO:0004519; GO:0004527; GO:0005739; GO:0090305; GO:0005634; GO:0008270,DNA binding; DNA recombination; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; cell cycle; endonuclease activity; exonuclease activity; mitochondrion; nucleic acid phosphodiester bond hydrolysis; nucleus; zinc ion binding,PF03372;PF06839;,5.00E-32,CHOYP_BRAFLDRAFT_124956.1.1,,,,,,,APEX2_BOVIN,Bos taurus (Bovine),base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310] comp58939_c0_seq1,255,43.5294,0.27686078,5,7,,2.00E-11,F1N9Y5,Tyrosine-protein kinase SYK (EC 2.7.10.2),Tyrosine-protein kinase SYK (EC 2.7.10.2),GO:0005524; GO:0019815; GO:0050853; GO:0042101; GO:0007257; GO:0002250; GO:0043366; GO:0048514; GO:0071226; GO:0005829; GO:0042742; GO:0032009; GO:0007167; GO:0045087; GO:0007229; GO:0007159; GO:0019370; GO:0001945; GO:0002281; GO:0002283; GO:0030593; GO:0004715; GO:0045579; GO:0046638; GO:0046641; GO:0045780; GO:0050850; GO:0033630; GO:0050715; GO:0045588; GO:0045425; GO:0045401; GO:0043306; GO:0050731; GO:0046777; GO:0004716; GO:0070372; GO:0090237; GO:0043313; GO:0050764; GO:0090330; GO:0032928; GO:0002554,ATP binding; B cell receptor complex; B cell receptor signaling pathway; T cell receptor complex; activation of JUN kinase activity; adaptive immune response; beta selection; blood vessel morphogenesis; cellular response to molecule of fungal origin; cytosol; defense response to bacterium; early phagosome; enzyme linked receptor protein signaling pathway; innate immune response; integrin-mediated signaling pathway; leukocyte cell-cell adhesion; leukotriene biosynthetic process; lymph vessel development; macrophage activation involved in immune response; neutrophil activation involved in immune response; neutrophil chemotaxis; non-membrane spanning protein tyrosine kinase activity; positive regulation of B cell differentiation; positive regulation of alpha-beta T cell differentiation; positive regulation of alpha-beta T cell proliferation; positive regulation of bone resorption; positive regulation of calcium-mediated signaling; positive regulation of cell adhesion mediated by integrin; positive regulation of cytokine secretion; positive regulation of gamma-delta T cell differentiation; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of interleukin-3 biosynthetic process; positive regulation of mast cell degranulation; positive regulation of peptidyl-tyrosine phosphorylation; protein autophosphorylation; receptor signaling protein tyrosine kinase activity; regulation of ERK1 and ERK2 cascade; regulation of arachidonic acid secretion; regulation of neutrophil degranulation; regulation of phagocytosis; regulation of platelet aggregation; regulation of superoxide anion generation; serotonin secretion by platelet,PF07714;PF00017;,,,,,,,,,KSYK_CHICK,Gallus gallus (Chicken),adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cellular response to molecule of fungal origin [GO:0071226]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of mast cell degranulation [GO:0043306]; protein phosphorylation [GO:0006468]; regulation of arachidonic acid secretion [GO:0090237]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; serotonin secretion by platelet [GO:0002554]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp58939_c1_seq1,344,47.6744,0.35964563,14,0,,,,,,,,,2.00E-14,CHOYP_LOC589201.1.1,,,,,,,,, comp58940_c0_seq1,320,42.1875,0.91998253,18,15,,1.00E-48,Q9C0H5,Rho GTPase-activating protein 39,Rho GTPase-activating protein 39,GO:0007411; GO:0005856; GO:0005829; GO:0005634; GO:0051056; GO:0007264,axon guidance; cytoskeleton; cytosol; nucleus; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00784;PF00620;PF00397;,4.00E-34,CHOYP_RHG39.1.1,3.00E-39,ruditapes_c17550,,,,,RHG39_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp58943_c0_seq1,360,61.3889,1.12406636,2,23,,3.00E-23,P06225,DNA polymerase (EC 2.7.7.7),DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-),GO:0003677; GO:0006260; GO:0003887; GO:0004527; GO:0090305,DNA binding; DNA replication; DNA-directed DNA polymerase activity; exonuclease activity; nucleic acid phosphodiester bond hydrolysis,PF00476;,,,,,,,,,DPOL_BPSP2,Bacillus phage SP02 (Bacteriophage SP02),viral DNA genome replication [GO:0039693] comp58968_c0_seq1,209,46.89,0.17759392,2,13,,4.00E-09,Q8WZA1,"Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)","Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)",GO:0000139; GO:0047223; GO:0016021; GO:0006493,"Golgi membrane; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; integral to membrane; protein O-linked glycosylation",PF03071;,,,,,,,,,PMGT1_HUMAN,Homo sapiens (Human),protein O-linked glycosylation [GO:0006493] comp58986_c0_seq1,306,44.4444,0.53860224,1,16,,4.00E-07,F7E235,Failed axon connections homolog,Failed axon connections homolog,GO:0016021,integral to membrane,PF17171;PF17172;,,,,,,,,,FAXC_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp58991_c0_seq1,206,46.6019,0.46961179,11,13,,3.00E-21,Q9Z1Q9,Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS),Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS),GO:0005524; GO:0002161; GO:0005739; GO:0006450; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; mitochondrion; regulation of translational fidelity; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00043;PF00133;,3.00E-14,CHOYP_BRAFLDRAFT_66627.1.1,,,,,,,SYVC_MOUSE,Mus musculus (Mouse),valyl-tRNA aminoacylation [GO:0006438] comp58995_c0_seq1,347,39.1931,0.97922891,7,34,,5.00E-30,Q28HW9,CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard),CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard),GO:0071595; GO:0030154; GO:0005789; GO:0016021; GO:0007399; GO:0006998; GO:0031965; GO:0048471; GO:0010867; GO:0006470; GO:0004722,Nem1-Spo7 phosphatase complex; cell differentiation; endoplasmic reticulum membrane; integral to membrane; nervous system development; nuclear envelope organization; nuclear membrane; perinuclear region of cytoplasm; positive regulation of triglyceride biosynthetic process; protein dephosphorylation; protein serine/threonine phosphatase activity,PF03031;,8.00E-50,CHOYP_ISCW_ISCW008600.1.1,,,,,,,CNEP1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell differentiation [GO:0030154]; nervous system development [GO:0007399]; nuclear envelope organization [GO:0006998]; positive regulation of triglyceride biosynthetic process [GO:0010867]; protein dephosphorylation [GO:0006470] comp59011_c0_seq1,287,41.8118,0.64448335,8,4,,9.00E-42,Q8TBZ3,WD repeat-containing protein 20 (Protein DMR),WD repeat-containing protein 20 (Protein DMR),,,PF00400;,,,,,,,,,WDR20_HUMAN,Homo sapiens (Human), comp59011_c1_seq1,208,39.4231,0.39188406,1,19,,5.00E-23,Q08274,Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein DMR-N9),Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein DMR-N9),,,PF00400;,2.00E-16,CHOYP_WDR20.1.1,,,,,,,DMWD_MOUSE,Mus musculus (Mouse), comp5902_c0_seq1,243,75.7202,1.21136803,0,7,,1.00E-07,P58388,3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) (Rhodanese-like protein),3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) (Rhodanese-like protein),GO:0016784; GO:0005737; GO:0004792,3-mercaptopyruvate sulfurtransferase activity; cytoplasm; thiosulfate sulfurtransferase activity,PF00581;,,,,,,,,,THTM_ECO57,Escherichia coli O157:H7, comp59058_c0_seq1,314,48.4076,0.0992136,12,15,,,,,,,,,5.00E-20,CHOYP_contig_018567,,,,,,,,, comp59073_c0_seq1,350,56,0.80404655,0,22,,7.00E-09,P46697,Probable peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Rotamase B),Probable peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Rotamase B),GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00160;,,,,,,,,,PPIB_MYCLE,Mycobacterium leprae (strain TN),protein folding [GO:0006457] comp59098_c0_seq1,456,44.7368,0.26480089,22,19,,6.00E-50,Q8IV38,Ankyrin repeat and MYND domain-containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,GO:0005929; GO:0046872,cilium; metal ion binding,PF12796;PF01753;,2.00E-33,CHOYP_ANKMY2.1.1,,,,,,,ANKY2_HUMAN,Homo sapiens (Human), comp59109_c0_seq1,246,45.5285,0.15752811,1,11,,2.00E-13,Q8N4W9,Zinc finger protein 808,Zinc finger protein 808,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN808_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp59124_c0_seq1,568,47.1831,0.66561035,6,33,,5.00E-34,P15062,Transforming protein p68/c-ets-1,Transforming protein p68/c-ets-1,GO:0005634; GO:0010595; GO:0045765; GO:0043565; GO:0003700; GO:0006351,"nucleus; positive regulation of endothelial cell migration; regulation of angiogenesis; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00178;PF02198;,,,,,,,,,ETS1B_CHICK,Gallus gallus (Chicken),"cell differentiation [GO:0030154]; positive regulation of endothelial cell migration [GO:0010595]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp59231_c0_seq1,856,44.3925,0.50880734,21,40,,6.00E-24,Q95K09,Gamma-tubulin complex component 5 (GCP-5) (Fragment),Gamma-tubulin complex component 5 (GCP-5) (Fragment),GO:0008274; GO:0005874; GO:0008017; GO:0007020; GO:0000922,gamma-tubulin ring complex; microtubule; microtubule binding; microtubule nucleation; spindle pole,PF04130;,,,,,,,,,GCP5_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),microtubule nucleation [GO:0007020] comp59238_c0_seq1,308,66.2338,1.09284972,0,13,,4.00E-08,Q9ZCE4,Uncharacterized protein RP812,Uncharacterized protein RP812,,,PF01722;,,,,,,,,,Y812_RICPR,Rickettsia prowazekii (strain Madrid E), comp59282_c0_seq1,288,46.5278,0.66898955,4,27,,1.00E-28,O95477,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0044255; GO:0071222; GO:0071300; GO:0015485; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0042157; GO:0007040; GO:0045121; GO:0010887; GO:0010745; GO:0002790; GO:0045335; GO:0006911; GO:0005543; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular lipid metabolic process; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol binding; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lipoprotein metabolic process; lysosome organization; membrane raft; negative regulation of cholesterol storage; negative regulation of macrophage derived foam cell differentiation; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid binding; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,,,,,,,,,ABCA1_HUMAN,Homo sapiens (Human),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp59328_c0_seq1,500,48,0.56327961,17,11,,2.00E-45,Q9JIM3,Putative DNA repair and recombination protein RAD26-like (EC 3.6.4.-),DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0005737; GO:0005815; GO:0005634,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; cytoplasm; microtubule organizing center; nucleus,PF00271;PF00176;PF14773;,3.00E-38,CHOYP_LOC100014225.1.1,,,,,,,RAD26_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281] comp59337_c0_seq1,400,47,0.54484036,5,22,,6.00E-10,P40483,Putative zinc metalloproteinase YIL108W (EC 3.4.24.-),Putative zinc metalloproteinase YIL108W (EC 3.4.24.-),GO:0005737; GO:0046872; GO:0008237; GO:0006508,cytoplasm; metal ion binding; metallopeptidase activity; proteolysis,PF12044;,4.00E-35,CHOYP_LOC100199415.1.1,,,,,,,YIK8_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast), comp59362_c0_seq1,630,42.8571,0.873673,13,20,,1.00E-27,Q9H4G4,Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2),Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2),GO:0000139; GO:0005576,Golgi membrane; extracellular region,PF00188;,2.00E-41,CHOYP_GAPR1.1.1,1.00E-11,ruditapes_c23133,,,,,GAPR1_HUMAN,Homo sapiens (Human),positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] comp59369_c0_seq1,212,72.1698,1.23797626,0,1,,1.00E-09,P46420,Glutathione S-transferase 4 (EC 2.5.1.18) (GST class-phi member 4) (GST-27) (GST-IV),Glutathione S-transferase 4 (EC 2.5.1.18) (GST class-phi member 4) (GST-27) (GST-IV),GO:0004364,glutathione transferase activity,PF00043;PF02798;,,,,,,,,,GSTF4_MAIZE,Zea mays (Maize), comp59378_c0_seq1,316,59.4937,1.14122615,0,26,,4.00E-45,Q655S1,"ATP-dependent zinc metalloprotease FTSH 2, chloroplastic (OsFTSH2) (EC 3.4.24.-)","ATP-dependent zinc metalloprotease FTSH 2, chloroplastic (OsFTSH2) (EC 3.4.24.-)",GO:0005524; GO:0009535; GO:0016021; GO:0046872; GO:0004222; GO:0017111; GO:0006508,ATP binding; chloroplast thylakoid membrane; integral to membrane; metal ion binding; metalloendopeptidase activity; nucleoside-triphosphatase activity; proteolysis,PF00004;PF01434;,,,,,,,,,FTSH2_ORYSJ,Oryza sativa subsp. japonica (Rice),photoinhibition [GO:0010205]; photosystem II repair [GO:0010206]; proteolysis [GO:0006508]; PSII associated light-harvesting complex II catabolic process [GO:0010304]; thylakoid membrane organization [GO:0010027] comp59400_c0_seq1,1094,40.0366,0.41096782,99,6,,7.00E-23,F5H4B4,Protein FAM227A,Protein FAM227A,,,PF14922;,2.00E-96,CHOYP_BRAFLDRAFT_85206.1.1,,,2.00E-66,AM864903.p.cg.6,5,male gonad,F227A_HUMAN,Homo sapiens (Human), comp59407_c0_seq1,541,46.7652,0.3469478,12,8,,6.00E-81,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,9.00E-96,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp59411_c0_seq1,828,45.0483,0.50210618,27,26,,6.00E-09,Q92870,Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1),Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1),GO:0007411; GO:0001540; GO:0007050; GO:0005737; GO:0030198; GO:0030426; GO:0035556; GO:0030027; GO:0016020; GO:0043066; GO:0030308; GO:0001764; GO:0005634; GO:0043065; GO:0006355; GO:0045202; GO:0008134,"axon guidance; beta-amyloid binding; cell cycle arrest; cytoplasm; extracellular matrix organization; growth cone; intracellular signal transduction; lamellipodium; membrane; negative regulation of apoptotic process; negative regulation of cell growth; neuron migration; nucleus; positive regulation of apoptotic process; regulation of transcription, DNA-dependent; synapse; transcription factor binding",PF00640;PF00397;,2.00E-17,CHOYP_PHUM_PHUM122670.1.1,,,,,,,APBB2_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; regulation of transcription, DNA-templated [GO:0006355]" comp59436_c0_seq1,268,37.3134,0,4,0,,4.00E-17,P38766,ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (Regulation of Ty1 transposition protein 104) (rDNA recombination mutation protein 3),ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (Regulation of Ty1 transposition protein 104) (rDNA recombination mutation protein 3),GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0006260; GO:0000002; GO:0005724; GO:0005657; GO:0097046; GO:0000723,ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; DNA replication; mitochondrial genome maintenance; nuclear telomeric heterochromatin; replication fork; replication fork progression beyond termination site; telomere maintenance,PF05970;,,,,,,,,,RRM3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),DNA repair [GO:0006281]; DNA replication [GO:0006260]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; replication fork progression beyond termination site [GO:0097046]; replication fork reversal [GO:0071932]; telomere maintenance [GO:0000723] comp59473_c0_seq1,555,42.7027,0.84084963,18,48,,4.00E-14,Q8N9F8,Zinc finger protein 454,Zinc finger protein 454,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN454_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp59485_c0_seq1,616,41.7208,0.84352696,18,35,,2.00E-37,Q6IMK3,DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein),DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein),GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF00226;PF00071;,4.00E-51,CHOYP_LOC100368102.1.1,4.00E-92,ruditapes2_c2735,,,,,DJC27_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),small GTPase mediated signal transduction [GO:0007264] comp59496_c0_seq1,416,44.9519,0.86276361,20,0,,4.00E-16,Q91ZI0,Cadherin EGF LAG seven-pass G-type receptor 3,Cadherin EGF LAG seven-pass G-type receptor 3,GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_MOUSE,Mus musculus (Mouse),axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp59504_c0_seq1,208,39.9038,0.48605775,0,18,,6.00E-09,Q1JQA0,Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-),Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-),GO:0006464; GO:0005764; GO:0008474,cellular protein modification process; lysosome; palmitoyl-(protein) hydrolase activity,PF02089;,,,,,,,,,PPT2_BOVIN,Bos taurus (Bovine), comp59523_c0_seq1,258,39.9225,0.30566942,0,12,,7.00E-18,Q6DHR8,Nogo-B receptor (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog),"Dehydrodolichyl diphosphate synthase complex subunit nus1 (EC 2.5.1.87) (Di-trans,poly-cis-decaprenylcistransferase) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)",GO:0005789; GO:0016021; GO:0006486; GO:0002040; GO:0016765,"endoplasmic reticulum membrane; integral to membrane; protein glycosylation; sprouting angiogenesis; transferase activity, transferring alkyl or aryl (other than methyl) groups",PF01255;,,,,,,,,,NGBR_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein glycosylation [GO:0006486]; sprouting angiogenesis [GO:0002040] comp5953_c0_seq1,257,39.6887,0.51191251,9,0,,1.00E-15,Q6P4Z6,Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1),Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1),GO:0008168,methyltransferase activity,PF04072;,,,,,,,,,LCMT1_RAT,Rattus norvegicus (Rat),C-terminal protein methylation [GO:0006481] comp59578_c0_seq1,252,43.254,1.02638533,8,15,,5.00E-13,Q80TC5,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,1.00E-20,CHOYP_LOC100560153.3.3,,,,,,,POGK_MOUSE,Mus musculus (Mouse),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp59586_c0_seq1,230,65.6522,1.30372835,0,12,,7.00E-19,P23669,Threonine synthase (TS) (EC 4.2.3.1),Threonine synthase (TS) (EC 4.2.3.1),GO:0030170; GO:0009088; GO:0004795,pyridoxal phosphate binding; threonine biosynthetic process; threonine synthase activity,PF00291;PF14821;,,,,,,,,,THRC_CORGL,Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025),threonine biosynthetic process [GO:0009088] comp59590_c0_seq1,316,60.443,0.90433208,0,5,,1.00E-09,O34738,Putative HMP/thiamine permease protein YkoE,Putative HMP/thiamine permease protein YkoE,GO:0016021; GO:0005886; GO:0006810,integral to membrane; plasma membrane; transport,PF09819;,,,,,,,,,YKOE_BACSU,Bacillus subtilis (strain 168),transport [GO:0006810] comp59593_c0_seq1,211,38.3886,0.13022406,5,0,,2.00E-18,Q5SPW0,Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog),Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog),GO:0000938; GO:0040007; GO:0048873; GO:0050881; GO:0060052; GO:0015031; GO:0042147,"GARP complex; growth; homeostasis of number of cells within a tissue; musculoskeletal movement; neurofilament cytoskeleton organization; protein transport; retrograde transport, endosome to Golgi",PF07928;PF10475;,,,,,,,,,VPS54_MOUSE,Mus musculus (Mouse),"Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp59598_c0_seq1,429,41.7249,0.43336088,14,28,,5.00E-16,O00189,AP-4 complex subunit mu-1 (AP-4 adapter complex mu subunit) (Adapter-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4),AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4),GO:0030119; GO:0006895; GO:0000138; GO:0030131; GO:0005905; GO:0006886; GO:0005802; GO:0005215,AP-type membrane coat adaptor complex; Golgi to endosome transport; Golgi trans cisterna; clathrin adaptor complex; coated pit; intracellular protein transport; trans-Golgi network; transporter activity,PF00928;PF01217;,,,,,,,,,AP4M1_HUMAN,Homo sapiens (Human),Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] comp59626_c0_seq1,325,42.1538,0.50599149,10,21,,2.00E-27,Q28GV1,Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2),Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2),GO:0030261; GO:0005634,chromosome condensation; nucleus,PF16858;PF06278;,,,,,,,,,CNDH2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),chromosome condensation [GO:0030261] comp59643_c0_seq1,233,39.9142,1.19389954,1,14,,4.00E-07,Q68EK2,Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor),Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor),GO:0001525; GO:0048844; GO:0004948; GO:0016021; GO:0005886; GO:0001756,angiogenesis; artery morphogenesis; calcitonin receptor activity; integral to membrane; plasma membrane; somitogenesis,PF00002;PF02793;,,,,,,,,,CALRL_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; cell surface receptor signaling pathway [GO:0007166]; somitogenesis [GO:0001756] comp59654_c0_seq1,289,65.0519,0.98640637,0,12,,5.00E-56,A1W8Z4,Translation initiation factor IF-2,Translation initiation factor IF-2,GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation initiation factor activity,PF11987;PF08364;PF04760;,,,,,,,,,IF2_ACISJ,Acidovorax sp. (strain JS42), comp59654_c1_seq1,229,66.8122,1.02715803,0,5,,5.00E-22,Q97I51,Translation initiation factor IF-2,Translation initiation factor IF-2,GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation initiation factor activity,PF11987;PF04760;,,,,,,,,,IF2_CLOAB,Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787), comp59682_c0_seq1,599,48.0801,1.04686234,14,21,,1.00E-14,Q2VLH6,Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],GO:0006953; GO:0005576; GO:0016021; GO:0005886; GO:0005044,acute-phase response; extracellular region; integral to membrane; plasma membrane; scavenger receptor activity,PF00530;,,,,,,,,,C163A_MOUSE,Mus musculus (Mouse),acute-phase response [GO:0006953] comp59682_c0_seq2,524,48.0916,1.02941551,0,7,,1.00E-08,O43866,CD5 antigen-like (CT-2) (IgM-associated peptide) (SP-alpha),CD5 antigen-like (Apoptosis inhibitor expressed by macrophages) (hAIM) (CT-2) (IgM-associated peptide) (SP-alpha),GO:0006915; GO:0006968; GO:0005615; GO:0016020; GO:0005044,apoptotic process; cellular defense response; extracellular space; membrane; scavenger receptor activity,PF00530;,,,,,,,,,CD5L_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; cellular defense response [GO:0006968]; immune system process [GO:0002376]; inflammatory response [GO:0006954] comp59687_c0_seq1,235,46.8085,0.81268689,7,0,,8.00E-12,Q4R5L5,Annexin A7 (Annexin VII) (Annexin-7),Annexin A7 (Annexin VII) (Annexin-7),GO:0005509; GO:0005544,calcium ion binding; calcium-dependent phospholipid binding,PF00191;,,,,,,,,,ANXA7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp59704_c0_seq1,299,48.8294,0.62347193,9,12,,2.00E-41,P27085,40S ribosomal protein S26,40S ribosomal protein S26,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01283;,3.00E-98,CHOYP_RS26.14.15,1.00E-76,ruditapes2_c278,,,,,RS26_OCTVU,Octopus vulgaris (Common octopus),translation [GO:0006412] comp59734_c0_seq1,351,43.8746,0.36115204,6,24,,5.00E-12,Q6PA97,Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein homolog),Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein homolog),GO:0005794; GO:0030154; GO:0005783,Golgi apparatus; cell differentiation; endoplasmic reticulum,PF08626;,,,,,,,,,TPPC9_XENLA,Xenopus laevis (African clawed frog),cell differentiation [GO:0030154] comp59735_c0_seq1,240,42.0833,1.03962589,0,16,,2.00E-07,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp59757_c0_seq1,387,40.8269,0.24967992,10,17,,2.00E-11,Q9EPW0,"Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)","Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)",GO:0016316; GO:0034597; GO:0006798,"phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity; polyphosphate catabolic process",,2.00E-13,CHOYP_LOC655115.1.1,,,,,,,INP4A_MOUSE,Mus musculus (Mouse),polyphosphate catabolic process [GO:0006798]; signal transduction [GO:0007165] comp5975_c0_seq1,311,45.0161,0.51453841,11,0,,5.00E-26,P12785,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0005794; GO:0070402; GO:0004313; GO:0004314; GO:0006084; GO:0071353; GO:0008144; GO:0047117; GO:0004319; GO:0006633; GO:0004312; GO:0042587; GO:0042470; GO:0005739; GO:0016295; GO:0004320; GO:0016296; GO:0005886; GO:0042803; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; Golgi apparatus; NADPH binding; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; acetyl-CoA metabolic process; cellular response to interleukin-4; drug binding; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; fatty acid synthase activity; glycogen granule; melanosome; mitochondrion; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; plasma membrane; protein homodimerization activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;,,,,,,,,,FAS_RAT,Rattus norvegicus (Rat),acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649] comp59776_c0_seq1,221,45.7014,0.78354545,3,19,,4.00E-06,Q9P215,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,,,,,,,,,POGK_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp59785_c1_seq1,958,41.7537,0.8652641,30,18,,,,,,,,,4.00E-27,CHOYP_MYLIP.2.3,,,,,,,,, comp59790_c0_seq1,255,45.4902,0.23167777,4,0,,2.00E-12,Q08D51,Autophagy-related protein 2 homolog A,Autophagy-related protein 2 homolog A,GO:0006914,autophagy,PF13329;PF09333;PF12624;,,,,,,,,,ATG2A_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp59820_c0_seq1,238,57.9832,0.96107517,0,7,,8.00E-25,A5CRV6,Tryptophan synthase beta chain (EC 4.2.1.20),Tryptophan synthase beta chain (EC 4.2.1.20),GO:0004834,tryptophan synthase activity,PF00291;,,,,,,,,,TRPB_CLAM3,Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382), comp59849_c0_seq1,530,47.9245,0.79146623,7,7,,9.00E-46,Q80V70,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF12662;PF07974;PF07645;PF00053;,2.00E-15,CHOYP_MEGF6.37.59,,,,,,,MEGF6_MOUSE,Mus musculus (Mouse), comp59856_c0_seq1,338,44.9704,0.42527254,12,15,,1.00E-30,Q6GNG3,Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3),Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3),GO:0045454; GO:0005789; GO:0006662; GO:0016021; GO:0003756; GO:0015035; GO:0006457,cell redox homeostasis; endoplasmic reticulum membrane; glycerol ether metabolic process; integral to membrane; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein folding,PF00085;,,,,,,,,,TMX3_XENLA,Xenopus laevis (African clawed frog),cell redox homeostasis [GO:0045454] comp59857_c0_seq1,208,41.8269,0.23196985,5,2,,2.00E-06,Q14159,DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair),DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair),GO:0072757; GO:0072711; GO:0071479; GO:0000724; GO:0000228; GO:2000781; GO:0031334; GO:0010569; GO:0070202,cellular response to camptothecin; cellular response to hydroxyurea; cellular response to ionizing radiation; double-strand break repair via homologous recombination; nuclear chromosome; positive regulation of double-strand break repair; positive regulation of protein complex assembly; regulation of double-strand break repair via homologous recombination; regulation of establishment of protein localization to chromosome,PF14950;PF14951;,,,,,,,,,K0146_HUMAN,Homo sapiens (Human),cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of protein complex assembly [GO:0031334]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of establishment of protein localization to chromosome [GO:0070202] comp59858_c1_seq1,222,45.4955,0.9971747,2,8,,1.00E-08,Q9P6J4,Uncharacterized protein C1683.06c,Uncharacterized protein C1683.06c,GO:0034356; GO:0005829; GO:0070635; GO:0019358; GO:0070636; GO:0005634; GO:0046135; GO:0008655; GO:0045437,NAD biosynthesis via nicotinamide riboside salvage pathway; cytosol; nicotinamide riboside hydrolase activity; nicotinate nucleotide salvage; nicotinic acid riboside hydrolase activity; nucleus; pyrimidine nucleoside catabolic process; pyrimidine-containing compound salvage; uridine nucleosidase activity,PF01156;,,,,,,,,,YHD6_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinate nucleotide salvage [GO:0019358]; purine nucleoside catabolic process [GO:0006152]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside catabolic process [GO:0046135] comp59878_c0_seq1,353,43.6261,0.61193231,1,23,,3.00E-07,Q570Y9,DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6),DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6),GO:0005622; GO:0035556; GO:0032007; GO:0045792; GO:0006469; GO:2001236,intracellular; intracellular signal transduction; negative regulation of TOR signaling cascade; negative regulation of cell size; negative regulation of protein kinase activity; regulation of extrinsic apoptotic signaling pathway,PF00610;,,,,,,,,,DPTOR_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] comp59885_c0_seq1,209,71.7703,1.05002404,0,1,,7.00E-23,Q21RH9,Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) (EC 6.3.5.-),Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) (EC 6.3.5.7),GO:0005524; GO:0050567; GO:0006412,ATP binding; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; translation,PF01425;,,,,,,,,,GATA_RHOFD,Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens),translation [GO:0006412] comp59897_c0_seq1,433,41.8014,0.42393389,16,6,,,,,,,,,,,9.00E-42,ruditapes_c17839,,,,,,, comp59927_c0_seq1,629,38.4738,1.1157053,14,75,,2.00E-10,Q8BUH7,Ring finger protein 26,Ring finger protein 26,GO:0016021; GO:0008270,integral to membrane; zinc ion binding,,3.00E-20,CHOYP_RNF26.1.1,,,,,,,RNF26_MOUSE,Mus musculus (Mouse), comp59935_c0_seq1,334,41.3174,0.83086062,10,26,,,,,,,,,,,1.00E-13,ruditapes_c31830,,,,,,, comp5994_c0_seq1,201,45.7711,0.38847115,7,0,,4.00E-07,Q9D119,Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1),Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1),GO:0010923; GO:0019902; GO:0004864,negative regulation of phosphatase activity; phosphatase binding; protein phosphatase inhibitor activity,PF12796;,,,,,,,,,PPR27_MOUSE,Mus musculus (Mouse),negative regulation of phosphatase activity [GO:0010923] comp59951_c0_seq1,481,41.9958,0.23708907,3,23,,1.00E-14,Q5ZL36,Protrudin (Zinc finger FYVE domain-containing protein 27),Protrudin (Zinc finger FYVE domain-containing protein 27),GO:0030424; GO:0030425; GO:0005783; GO:0005789; GO:0032584; GO:0016021; GO:0046872; GO:0031175; GO:0048011; GO:0072659; GO:0055038,axon; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; growth cone membrane; integral to membrane; metal ion binding; neuron projection development; neurotrophin TRK receptor signaling pathway; protein localization to plasma membrane; recycling endosome membrane,PF01363;,,,,,,,,,ZFY27_CHICK,Gallus gallus (Chicken),neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; protein localization to plasma membrane [GO:0072659] comp59958_c0_seq1,677,40.6204,0.5384953,34,25,,1.00E-06,Q8NA66,Cyclic nucleotide-binding domain-containing protein 1,Cyclic nucleotide-binding domain-containing protein 1,,,,2.00E-35,CHOYP_LOC100378053.1.1,,,,,,,CNBD1_HUMAN,Homo sapiens (Human), comp59971_c0_seq1,283,38.8693,0.75734279,15,14,,6.00E-13,Q9W2U4,Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2-related protein),Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2-related protein),GO:0000278; GO:0022008,mitotic cell cycle; neurogenesis,PF09184;,,,,,,,,,PP4R2_DROME,Drosophila melanogaster (Fruit fly),mitotic cell cycle [GO:0000278]; neurogenesis [GO:0022008]; regulation of protein dephosphorylation [GO:0035304] comp59972_c1_seq1,432,46.0648,0.39363847,7,0,,6.00E-58,Q9UMX1,Suppressor of fused homolog (SUFUH),Suppressor of fused homolog (SUFUH),GO:0005737; GO:0042994; GO:0001947; GO:0045668; GO:2000059; GO:0043433; GO:0045879; GO:1901621; GO:0042992; GO:0000122; GO:0001843; GO:0005634; GO:0072372; GO:0006508; GO:0004871; GO:0001501; GO:0043588; GO:0021776; GO:0021775; GO:0003714; GO:0008134,cytoplasm; cytoplasmic sequestering of transcription factor; heart looping; negative regulation of osteoblast differentiation; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of smoothened signaling pathway; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; negative regulation of transcription factor import into nucleus; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; primary cilium; proteolysis; signal transducer activity; skeletal system development; skin development; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; smoothened signaling pathway involved in ventral spinal cord interneuron specification; transcription corepressor activity; transcription factor binding,PF05076;PF12470;,9.00E-19,CHOYP_LOC100313743.2.2,,,,,,,SUFU_HUMAN,Homo sapiens (Human),"aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart looping [GO:0001947]; multicellular organism development [GO:0007275]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skin development [GO:0043588]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; ventricular septum development [GO:0003281]" comp59999_c0_seq1,221,61.5385,0.9635614,0,15,,1.00E-06,Q72SI0,Ferrous iron transport protein B,Ferrous iron transport protein B,GO:0005525; GO:0015093; GO:0016021; GO:0055072; GO:0005886,GTP binding; ferrous iron transmembrane transporter activity; integral to membrane; iron ion homeostasis; plasma membrane,PF07664;PF02421;PF07670;,,,,,,,,,FEOB_LEPIC,Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130),iron ion homeostasis [GO:0055072] comp60045_c0_seq1,346,44.2197,0.48959845,3,18,,4.00E-22,Q6JAN0,G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1),GO:0004930; GO:0042462; GO:0016021; GO:0007218; GO:0005886,G-protein coupled receptor activity; eye photoreceptor cell development; integral to membrane; neuropeptide signaling pathway; plasma membrane,PF00002;PF03160;,,,,,,,,,GPR98_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462] comp60053_c0_seq1,204,43.1373,0.31833063,0,11,,2.00E-08,O88923,Latrophilin-2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2),Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2),GO:0004930; GO:0007420; GO:0030246; GO:0016021; GO:0043005; GO:0007218; GO:0005886,G-protein coupled receptor activity; brain development; carbohydrate binding; integral to membrane; neuron projection; neuropeptide signaling pathway; plasma membrane,PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;,,,,,,,,,LPHN2_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166] comp60083_c0_seq1,238,44.958,0.58868034,0,19,,6.00E-06,Q5DRC2,Protocadherin gamma-A1 (PCDH-gamma-A1),Protocadherin gamma-A1 (PCDH-gamma-A1),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG1_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp60083_c1_seq1,300,41.3333,0.70474248,4,7,,7.00E-06,Q96JQ0,Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1),Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1),GO:0005509; GO:0016339; GO:0007156; GO:0016021; GO:0016020; GO:0005886,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to membrane; membrane; plasma membrane,PF00028;,,,,,,,,,PCD16_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cochlea development [GO:0090102]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; post-anal tail morphogenesis [GO:0036342] comp60092_c1_seq1,231,45.8874,0.75653592,3,13,,2.00E-33,Q9VKJ0,"Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)","Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)",GO:0006559; GO:0004411; GO:0046872; GO:0006572,"L-phenylalanine catabolic process; homogentisate 1,2-dioxygenase activity; metal ion binding; tyrosine catabolic process",PF04209;,,,,,,,,,HGD_DROME,Drosophila melanogaster (Fruit fly),L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp60106_c0_seq1,224,57.1429,1.43139628,0,11,,7.00E-44,Q6A917,Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase),Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase),GO:0044205; GO:0006207; GO:0016597; GO:0004070; GO:0006520,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; amino acid binding; aspartate carbamoyltransferase activity; cellular amino acid metabolic process,PF00185;PF02729;,,,,,,,,,PYRB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520] comp60109_c0_seq1,270,46.6667,0.54748226,13,1,,3.00E-39,Q9P2R3,Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif),Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif),GO:0010008; GO:0005765; GO:0046872,endosome membrane; lysosomal membrane; metal ion binding,PF00023;PF12796;PF00651;PF01363;,3.00E-41,CHOYP_LOC100372945.2.2,,,,,,,ANFY1_HUMAN,Homo sapiens (Human),"endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" comp60112_c0_seq1,237,43.4599,0.63540414,6,12,,4.00E-17,Q1LXE6,Tetratricopeptide repeat protein 39C (TPR repeat protein 39C),Tetratricopeptide repeat protein 39C (TPR repeat protein 39C),,,PF10300;,,,,,,,,,TT39C_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474] comp60112_c1_seq1,445,38.6517,0.64525789,12,6,,2.00E-06,Q8BYY4,Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),,,PF10300;PF13174;,6.00E-21,CHOYP_TT39C.1.1,,,,,,,TT39B_MOUSE,Mus musculus (Mouse), comp60132_c0_seq1,501,47.3054,0.67736402,23,9,,6.00E-16,A2T929,Retinoic acid receptor RXR-alpha-A (Nuclear receptor subfamily 2 group B member 1-A) (RXRalpha-B) (Retinoid X receptor alpha-A),Retinoic acid receptor RXR-alpha-A (Nuclear receptor subfamily 2 group B member 1-A) (RXRalpha-B) (Retinoid X receptor alpha-A),GO:0005634; GO:0043565; GO:0003700; GO:0003707; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription, DNA-dependent; zinc ion binding",PF00104;PF11825;PF00105;,6.00E-28,CHOYP_NR2.1.1,,,,,,,RXRAA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"transcription, DNA-templated [GO:0006351]" comp60239_c1_seq1,203,45.3202,0.97145215,6,0,,2.00E-13,P81122,Insulin receptor substrate 2 (IRS-2) (4PS),Insulin receptor substrate 2 (IRS-2) (4PS),GO:0007420; GO:0008283; GO:0005829; GO:0008286; GO:0030879; GO:0002903; GO:0033673; GO:0010748; GO:0043548; GO:0005543; GO:0005886; GO:0030890; GO:0030335; GO:0032000; GO:0046326; GO:0045725; GO:0032024; GO:0002053; GO:0019901; GO:0009749; GO:0004871,brain development; cell proliferation; cytosol; insulin receptor signaling pathway; mammary gland development; negative regulation of B cell apoptotic process; negative regulation of kinase activity; negative regulation of plasma membrane long-chain fatty acid transport; phosphatidylinositol 3-kinase binding; phospholipid binding; plasma membrane; positive regulation of B cell proliferation; positive regulation of cell migration; positive regulation of fatty acid beta-oxidation; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of insulin secretion; positive regulation of mesenchymal cell proliferation; protein kinase binding; response to glucose stimulus; signal transducer activity,PF02174;PF00169;,,,,,,,,,IRS2_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway [GO:0008286]; mammary gland development [GO:0030879]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of kinase activity [GO:0033673]; negative regulation of plasma membrane long-chain fatty acid transport [GO:0010748]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of lipid metabolic process [GO:0019216]; response to glucose [GO:0009749] comp60243_c0_seq1,266,57.1429,1.11639208,1,14,,1.00E-12,Q8DVR0,Biofilm regulatory protein A,Biofilm regulatory protein A,GO:0031975; GO:0009405; GO:0001101,envelope; pathogenesis; response to acid,PF03816;,,,,,,,,,BRPA_STRMU,Streptococcus mutans serotype c (strain ATCC 700610 / UA159),pathogenesis [GO:0009405] comp60264_c0_seq2,696,41.092,0.41032999,4,0,,1.00E-06,Q6A000,Uncharacterized protein KIAA0753,Protein moonraker (MNR),,,PF15718;,,,,,,,,,K0753_MOUSE,Mus musculus (Mouse),centriole replication [GO:0007099]; protein localization to centrosome [GO:0071539] comp60302_c0_seq1,487,62.0123,1.05782353,10,21,,3.00E-57,P0C1D9,Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase),Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase),GO:0071266; GO:0003942; GO:0051287; GO:0050661; GO:0004073; GO:0005737; GO:0019877; GO:0009097; GO:0009089; GO:0009088,'de novo' L-methionine biosynthetic process; N-acetyl-gamma-glutamyl-phosphate reductase activity; NAD binding; NADP binding; aspartate-semialdehyde dehydrogenase activity; cytoplasm; diaminopimelate biosynthetic process; isoleucine biosynthetic process; lysine biosynthetic process via diaminopimelate; threonine biosynthetic process,PF01118;PF02774;,,,,,,,,,DHAS_CORML,Corynebacterium melassecola,'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088] comp60304_c0_seq1,285,71.2281,1.08724828,0,16,,5.00E-18,Q65N90,DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III),DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0046872,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; metal ion binding,PF01131;PF01751;,,,,,,,,,TOP3_BACLD,Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46),DNA topological change [GO:0006265] comp60308_c0_seq1,585,40,0.08793543,21,9,,2.00E-11,O83142,Probable 5'-nucleotidase (EC 3.1.3.5),Probable 5'-nucleotidase (EC 3.1.3.5),GO:0008253; GO:0046872; GO:0000166; GO:0009166; GO:0005886,5'-nucleotidase activity; metal ion binding; nucleotide binding; nucleotide catabolic process; plasma membrane,PF02872;PF00149;,3.00E-45,CHOYP_LOC591937.1.1,,,,,,,5NTD_TREPA,Treponema pallidum (strain Nichols),nucleotide catabolic process [GO:0009166] comp6031_c0_seq1,281,37.7224,0.70300036,3,4,,4.00E-15,A4D0V7,Cadherin-like and PC-esterase domain-containing protein 1,Cadherin-like and PC-esterase domain-containing protein 1,GO:0005783,endoplasmic reticulum,PF12733;,,,,,,,,,CPED1_HUMAN,Homo sapiens (Human), comp60357_c0_seq1,302,37.7483,1.03382027,7,16,,3.00E-10,Q28BQ6,Transmembrane emp24 domain-containing protein 1 (p24 family protein gamma-1) (p24gamma1),Transmembrane emp24 domain-containing protein 1 (p24 family protein gamma-1) (p24gamma1),GO:0005794; GO:0005789; GO:0033116; GO:0016021; GO:0005886; GO:0015031,Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; plasma membrane; protein transport,PF01105;,,,,,,,,,TMED1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein transport [GO:0015031] comp60393_c0_seq1,229,49.345,1.03605579,0,14,,2.00E-10,Q9HFY6,Calmodulin (CaM),Calmodulin (CaM),GO:0005509,calcium ion binding,PF13499;,8.00E-35,CHOYP_DGRI_GH12737.1.1,2.00E-46,ruditapes_c14521,,,,,CALM_BLAEM,Blastocladiella emersonii (Aquatic fungus), comp60404_c0_seq1,213,46.0094,0.62496163,8,9,,,,,,,,,6.00E-11,CHOYP_BRAFLDRAFT_128562.2.4,,,,,,,,, comp60417_c0_seq1,443,43.7923,0.52107382,13,17,,3.00E-15,Q99758,ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),GO:0005524; GO:0042626; GO:0097208; GO:0097233; GO:0016021; GO:0005886; GO:0042493,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; alveolar lamellar body; alveolar lamellar body membrane; integral to membrane; plasma membrane; response to drug",PF00005;,,,,,,,,,ABCA3_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp60418_c0_seq1,467,45.3961,0.47026798,18,39,,1.00E-37,Q17R14,Unconventional myosin-Id,Unconventional myosin-Id,GO:0005524; GO:0003774; GO:0016459; GO:0010923,ATP binding; motor activity; myosin complex; negative regulation of phosphatase activity,PF00612;PF00063;PF06017;,2.00E-26,CHOYP_LOC373223.1.1,,,,,,,MYO1D_BOVIN,Bos taurus (Bovine),cellular localization [GO:0051641]; early endosome to recycling endosome transport [GO:0061502]; negative regulation of phosphatase activity [GO:0010923] comp60442_c0_seq1,301,42.1927,0.91934044,6,0,,3.00E-21,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,2.00E-11,CHOYP_BRAFLDRAFT_119774.4.4,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp60442_c1_seq1,272,39.7059,1.0330377,2,6,,2.00E-21,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp60450_c0_seq1,210,34.2857,1.19889082,2,11,,3.00E-12,P91119,"Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)","Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)",GO:0004114; GO:0008152; GO:0046872; GO:0007165,"3',5'-cyclic-nucleotide phosphodiesterase activity; metabolic process; metal ion binding; signal transduction",PF01590;PF00233;,,,,,,,,,PDE5_CAEEL,Caenorhabditis elegans,chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP biosynthetic process [GO:0030827]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542] comp60479_c0_seq1,276,35.5072,0.46321678,6,28,,7.00E-07,Q08BB2,Probable carboxypeptidase PM20D1.2 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1.2),Probable carboxypeptidase PM20D1.2 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1.2),GO:0005576; GO:0046872; GO:0008233; GO:0006508,extracellular region; metal ion binding; peptidase activity; proteolysis,PF07687;PF01546;,,,,,,,,,P2012_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),peptide catabolic process [GO:0043171] comp60490_c0_seq1,553,39.9638,0.42945877,35,4,,2.00E-17,Q80U95,Ubiquitin-protein ligase E3C (EC 6.3.2.-),Ubiquitin-protein ligase E3C (EC 6.3.2.-),GO:0005737; GO:0005634; GO:0000209; GO:0042787; GO:0004842,cytoplasm; nucleus; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF00632;,,,,,,,,,UBE3C_MOUSE,Mus musculus (Mouse),protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp60510_c0_seq1,224,45.9821,1.2295327,0,11,,3.00E-26,Q64611,Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase),Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase),GO:0019752; GO:0005829; GO:0030170; GO:0004782; GO:0042412,carboxylic acid metabolic process; cytosol; pyridoxal phosphate binding; sulfinoalanine decarboxylase activity; taurine biosynthetic process,PF00282;,,,,,,,,,CSAD_RAT,Rattus norvegicus (Rat),sulfur amino acid catabolic process [GO:0000098]; taurine biosynthetic process [GO:0042412] comp60558_c0_seq1,220,44.0909,0.86105675,0,18,,2.00E-09,Q27874,Integrin beta pat-3 (Paralyzed arrest at two-fold protein 3),Integrin beta pat-3 (Paralyzed arrest at two-fold protein 3),GO:0031430; GO:0007155; GO:0009986; GO:0008305; GO:0007229; GO:0007275; GO:0055001; GO:0043005; GO:0043025; GO:0040017; GO:0004872; GO:0055120,M band; cell adhesion; cell surface; integrin complex; integrin-mediated signaling pathway; multicellular organismal development; muscle cell development; neuron projection; neuronal cell body; positive regulation of locomotion; receptor activity; striated muscle dense body,PF07974;PF08725;PF07965;PF00362;,,,,,,,,,PAT3_CAEEL,Caenorhabditis elegans,cell adhesion [GO:0007155]; integrin-mediated signaling pathway [GO:0007229]; muscle cell development [GO:0055001]; positive regulation of distal tip cell migration [GO:1903356]; positive regulation of locomotion [GO:0040017]; positive regulation of myosin II filament organization [GO:1904901]; positive regulation of ovulation [GO:0060279]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of actin cytoskeleton organization [GO:0032956] comp60578_c0_seq1,441,39.6825,0.80847032,5,31,,4.00E-23,Q9P2Y5,UV radiation resistance-associated gene protein (p63),UV radiation resistance-associated gene protein (p63),GO:0006281; GO:0005769; GO:0005770; GO:0005764; GO:0010508; GO:0043234,DNA repair; early endosome; late endosome; lysosome; positive regulation of autophagy; protein complex,PF10186;,,,,,,,,,UVRAG_HUMAN,Homo sapiens (Human),"autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; centrosome organization [GO:0051297]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; maintenance of Golgi location [GO:0051684]; multivesicular body sorting pathway [GO:0071985]; positive regulation of autophagy [GO:0010508]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of vesicle-mediated transport [GO:0060627]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; SNARE complex assembly [GO:0035493]; spindle organization [GO:0007051]; viral entry into host cell [GO:0046718]" comp60596_c0_seq1,231,65.8009,1.24863451,0,17,,8.00E-06,B9KNZ1,50S ribosomal protein L34,50S ribosomal protein L34,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00468;,,,,,,,,,RL34_RHOSK,Rhodobacter sphaeroides (strain KD131 / KCTC 12085),translation [GO:0006412] comp60609_c0_seq1,276,66.3043,1.16584022,2,15,,4.00E-54,Q6AAP6,Cobyric acid synthase,Cobyric acid synthase,GO:0009236; GO:0015420; GO:0006541,cobalamin biosynthetic process; cobalamin-transporting ATPase activity; glutamine metabolic process,PF01656;PF07685;,,,,,,,,,COBQ_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cobalamin biosynthetic process [GO:0009236]; glutamine metabolic process [GO:0006541] comp60616_c0_seq1,317,38.8013,0.42673533,16,14,,2.00E-43,F8W2M1,E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1),E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1),GO:0032580; GO:0000139; GO:0007030; GO:0017137; GO:0007049; GO:0005783; GO:0061025; GO:0070936; GO:0042787; GO:0030334; GO:0004842,Golgi cisterna membrane; Golgi membrane; Golgi organization; Rab GTPase binding; cell cycle; endoplasmic reticulum; membrane fusion; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of cell migration; ubiquitin-protein ligase activity,PF12796;PF00632;,3.00E-35,CHOYP_HACE1.1.2,,,,,,,HACE1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell migration [GO:0030334] comp60634_c0_seq1,266,47.7444,0.79504846,0,14,,5.00E-12,P23818,"Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)","Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)",GO:0004971; GO:0032281; GO:0030054; GO:0009986; GO:0032590; GO:0043197; GO:0005783; GO:0005789; GO:0005234; GO:0007616; GO:0043025; GO:0014069; GO:0045211; GO:0031623; GO:0007268; GO:0008021,alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; cell junction; cell surface; dendrite membrane; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; extracellular-glutamate-gated ion channel activity; long-term memory; neuronal cell body; postsynaptic density; postsynaptic membrane; receptor internalization; synaptic transmission; synaptic vesicle,PF01094;PF00060;PF10613;,,,,,,,,,GRIA1_MOUSE,Mus musculus (Mouse),chemical synaptic transmission [GO:0007268]; long-term memory [GO:0007616]; long term synaptic depression [GO:0060292]; receptor internalization [GO:0031623] comp60636_c0_seq1,284,48.9437,0.81897567,2,17,,9.00E-26,P51658,Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239),GO:0004303; GO:0001701; GO:0016021; GO:0001890; GO:0032526; GO:0006694; GO:0047035,estradiol 17-beta-dehydrogenase activity; in utero embryonic development; integral to membrane; placenta development; response to retinoic acid; steroid biosynthetic process; testosterone dehydrogenase (NAD+) activity,PF00106;,,,,,,,,,DHB2_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694] comp60649_c0_seq1,441,59.4104,1.18478553,0,28,,5.00E-10,C1FTC4,Cysteine desulfurase (EC 2.8.1.7),Cysteine desulfurase IscS (EC 2.8.1.7),GO:0031071; GO:0006534; GO:0030170,cysteine desulfurase activity; cysteine metabolic process; pyridoxal phosphate binding,PF00266;,,,,,,,,,ISCS_CLOBJ,Clostridium botulinum (strain Kyoto / Type A2),[2Fe-2S] cluster assembly [GO:0044571]; cellular amino acid metabolic process [GO:0006520] comp60656_c0_seq1,261,62.069,0.96079217,0,4,,2.00E-10,O34364,"Probable oligo-1,6-glucosidase 2 (EC 3.2.1.10) (Oligosaccharide alpha-1,6-glucosidase 2) (Sucrase-isomaltase 2) (Isomaltase 2)","Probable oligo-1,6-glucosidase 2 (EC 3.2.1.10) (Oligosaccharide alpha-1,6-glucosidase 2) (Sucrase-isomaltase 2) (Isomaltase 2)",GO:0005975; GO:0043169; GO:0005737; GO:0004574,"carbohydrate metabolic process; cation binding; cytoplasm; oligo-1,6-glucosidase activity",PF00128;PF16657;,,,,,,,,,O16G2_BACSU,Bacillus subtilis (strain 168),carbohydrate metabolic process [GO:0005975] comp60673_c1_seq1,287,47.7352,0.38315321,6,0,,8.00E-32,Q4VC17,A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-),GO:0004222; GO:0005578; GO:0006508; GO:0008270,metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF08686;PF01421;PF00090;,3.00E-28,CHOYP_ATS18.2.2,,,,,,,ATS18_MOUSE,Mus musculus (Mouse),eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331] comp60685_c0_seq1,230,51.7391,1.17526247,0,8,,1.00E-14,P63383,UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A),UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A),GO:0005524; GO:0006200; GO:0043190; GO:0016887; GO:0003677; GO:0009432; GO:0005737; GO:0009381; GO:0009380; GO:0090305; GO:0006289; GO:0006810; GO:0008270,ATP binding; ATP catabolic process; ATP-binding cassette (ABC) transporter complex; ATPase activity; DNA binding; SOS response; cytoplasm; excinuclease ABC activity; excinuclease repair complex; nucleic acid phosphodiester bond hydrolysis; nucleotide-excision repair; transport; zinc ion binding,PF00005;,,,,,,,,,UVRA_STAAN,Staphylococcus aureus (strain N315),nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432] comp60696_c0_seq1,209,72.2488,0.9582529,0,11,,1.00E-06,A7HD43,Globin-coupled histidine kinase (EC 2.7.13.3) (AfGcHK) (Heme-based oxygen-sensor histidine kinase),Globin-coupled histidine kinase (EC 2.7.13.3) (AfGcHK) (Heme-based oxygen-sensor histidine kinase),GO:0005524; GO:0020037; GO:0005506; GO:0016020; GO:0019825; GO:0015671; GO:0000155; GO:0042803,ATP binding; heme binding; iron ion binding; membrane; oxygen binding; oxygen transport; phosphorelay sensor kinase activity; protein homodimerization activity,PF02518;PF00512;,,,,,,,,,GCHK_ANADF,Anaeromyxobacter sp. (strain Fw109-5),peptidyl-histidine phosphorylation [GO:0018106]; phosphorelay signal transduction system [GO:0000160] comp60709_c0_seq2,317,51.1041,0.81578493,7,5,,,,,,,,,8.00E-18,CHOYP_LOC100214376.1.1,,,,,,,,, comp60715_c0_seq1,204,42.6471,0.43618069,0,26,,2.00E-08,Q02979,Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46),Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46),GO:0005737; GO:0006071; GO:0047389; GO:0008889; GO:0046475,cytoplasm; glycerol metabolic process; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; glycerophospholipid catabolic process,PF12796;PF03009;PF03105;,5.00E-31,CHOYP_V014.1.1,,,,,,,GDE1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475] comp60727_c0_seq1,517,46.4217,0.36468737,6,56,,1.00E-82,O95258,Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14),Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14),GO:0009060; GO:0005887; GO:0005743; GO:0006839; GO:0005739; GO:0006810,aerobic respiration; integral to plasma membrane; mitochondrial inner membrane; mitochondrial transport; mitochondrion; transport,PF00153;,8.00E-33,CHOYP_KMCP1.2.2,,,,,,,UCP5_HUMAN,Homo sapiens (Human),aerobic respiration [GO:0009060]; mitochondrial transport [GO:0006839]; proton transport [GO:0015992]; translation [GO:0006412]; transport [GO:0006810] comp60736_c0_seq1,301,45.8472,0.38067647,11,6,,3.00E-14,A2BDA5,DDB1- and CUL4-associated factor 15,DDB1- and CUL4-associated factor 15,GO:0016567,protein ubiquitination,PF14939;,1.00E-28,CHOYP_DCA15.1.1,,,,,,,DCA15_XENLA,Xenopus laevis (African clawed frog),protein ubiquitination [GO:0016567] comp60788_c0_seq1,485,41.4433,0.67446758,26,28,,9.00E-15,Q6PBN5,Ancient ubiquitous protein 1,Ancient ubiquitous protein 1,GO:0005789; GO:0016021; GO:0016746,"endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups",PF02845;,,,,,,,,,AUP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433] comp60811_c1_seq1,280,59.2857,0.98410711,3,6,,4.00E-59,Q6A7L2,4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (EC 1.17.7.1) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase),4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (EC 1.17.7.3) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase),GO:0051539; GO:0046429; GO:0005506; GO:0019288; GO:0016114,"4 iron, 4 sulfur cluster binding; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity; iron ion binding; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; terpenoid biosynthetic process",PF04551;,,,,,,,,,ISPG_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]" comp60854_c0_seq1,1083,41.3666,0.51974872,82,48,,8.00E-63,Q9NRL2,Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1),Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1),GO:0016590; GO:0008623; GO:0006261; GO:0006338; GO:0000228; GO:0006355; GO:0006351; GO:0008270,"ACF complex; CHRAC; DNA-dependent DNA replication; chromatin remodeling; nuclear chromosome; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF02791;PF00628;PF10537;PF15612;PF15613;,5.00E-46,CHOYP_BAZ1A.1.1,4.00E-19,ruditapes_c14023,,,,,BAZ1A_HUMAN,Homo sapiens (Human),"chromatin remodeling [GO:0006338]; DNA-dependent DNA replication [GO:0006261]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp60855_c0_seq1,266,33.8346,0.40050566,4,0,,1.00E-08,Q04095,Gag-Pro-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; p3; Capsid protein p27; Nucleocapsid protein p12; Protease p15 (EC 3.4.23.-); Reverse transcriptase beta-subunit (RT-beta) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Reverse transcriptase alpha-subunit (RT-alpha) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (pp32); p4],Gag-Pro-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; p3; Capsid protein p27; Nucleocapsid protein p12; Protease p15 (EC 3.4.23.-); Reverse transcriptase beta-subunit (RT-beta) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Reverse transcriptase alpha-subunit (RT-alpha) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (pp32); p4],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0090305; GO:0006508; GO:0004523; GO:0005198; GO:0019028; GO:0046718; GO:0008270,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; structural molecule activity; viral capsid; viral entry into host cell; zinc ion binding,PF00607;PF00552;PF02022;PF02813;PF00665;PF00077;PF00078;PF06817;PF00098;,,,,,,,,,POL_RSVSA,Avian leukosis virus RSA (RSV-SRA) (Rous sarcoma virus (strain Schmidt-Ruppin A)),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp60855_c0_seq2,278,33.4532,0.3925942,2,0,,5.00E-07,P04589,Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide p2; Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN)],Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0075713; GO:0004533; GO:0030430; GO:0042025; GO:0020002; GO:0039651; GO:0016020; GO:0090305; GO:0006508; GO:0004523; GO:0005198; GO:0039604; GO:0046718; GO:0019013; GO:0075732; GO:0046797; GO:0008270,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; establishment of integrated proviral latency; exoribonuclease H activity; host cell cytoplasm; host cell nucleus; host cell plasma membrane; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process; membrane; nucleic acid phosphodiester bond hydrolysis; proteolysis; ribonuclease H activity; structural molecule activity; suppression by virus of host translation; viral entry into host cell; viral nucleocapsid; viral penetration into host nucleus; viral procapsid maturation; zinc ion binding,PF00540;PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF06815;PF06817;PF00098;,,,,,,,,,POL_HV1EL,Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]; viral release from host cell [GO:0019076] comp60889_c0_seq1,230,41.3043,0.30745923,9,0,,5.00E-13,O93295,Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase),Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase),GO:0005524; GO:0016787; GO:0016021; GO:0046872; GO:0005886,ATP binding; hydrolase activity; integral to membrane; metal ion binding; plasma membrane,PF01150;,,,,,,,,,ENTP8_CHICK,Gallus gallus (Chicken), comp60913_c0_seq1,309,42.7184,0.60979247,11,16,,8.00E-08,Q5FWF4,DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],GO:0005524; GO:0003677; GO:0006281; GO:0036292; GO:0070530; GO:0036310; GO:0004520; GO:0004386; GO:0045910; GO:0043596; GO:0031297; GO:0048478; GO:0009411; GO:0008270,ATP binding; DNA binding; DNA repair; DNA rewinding; K63-linked polyubiquitin binding; annealing helicase activity; endodeoxyribonuclease activity; helicase activity; negative regulation of DNA recombination; nuclear replication fork; replication fork processing; replication fork protection; response to UV; zinc ion binding,PF00271;PF01844;PF00176;PF00641;,,,,,,,,,ZRAB3_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411] comp60927_c0_seq1,287,60.9756,0.61440746,0,29,,7.00E-16,P0CE53,Transposase InsH for insertion sequence element IS5H,Transposase InsH for insertion sequence element IS5H,GO:0003677; GO:0004803; GO:0006313,"DNA binding; transposase activity; transposition, DNA-mediated",PF01609;PF05598;,,,,,,,,,INSH6_ECOLI,Escherichia coli (strain K12),"transposition, DNA-mediated [GO:0006313]" comp60929_c0_seq1,570,40.7018,0.46678206,24,20,,1.00E-17,Q5QJC4,DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A),DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A),GO:0016787; GO:0005654; GO:0000715,"hydrolase activity; nucleoplasm; nucleotide-excision repair, DNA damage recognition",PF07522;,,,,,,,,,DCR1A_CHICK,Gallus gallus (Chicken),"DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protection from non-homologous end joining at telomere [GO:0031848]" comp60935_c0_seq1,253,33.5968,0.98560298,3,21,,4.00E-06,Q8TF20,Zinc finger protein 721,Zinc finger protein 721,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN721_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp60940_c0_seq1,564,40.7801,0.27784695,13,35,,2.00E-21,Q9NX74,tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.-) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2),tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.-) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2),GO:0005737; GO:0003725; GO:0005783; GO:0050660; GO:0005739; GO:0060548; GO:0004860; GO:0017150; GO:0002943,cytoplasm; double-stranded RNA binding; endoplasmic reticulum; flavin adenine dinucleotide binding; mitochondrion; negative regulation of cell death; protein kinase inhibitor activity; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF00035;PF01207;,,,,,,,,,DUS2L_HUMAN,Homo sapiens (Human),negative regulation of cell death [GO:0060548] comp60959_c0_seq1,414,40.0966,0.30336434,5,17,,9.00E-43,Q8AWB5,"Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)","Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)",GO:0032580; GO:0046920; GO:0036065; GO:0016021; GO:0006486,Golgi cisterna membrane; alpha-(1->3)-fucosyltransferase activity; fucosylation; integral to membrane; protein glycosylation,PF17039;PF00852;,8.00E-26,CHOYP_LOC100369391.1.1,,,,,,,FUT10_CHICK,Gallus gallus (Chicken),protein glycosylation [GO:0006486] comp60973_c0_seq1,661,44.0242,0.50404608,14,25,,3.00E-122,Q96RV3,Pecanex-like protein 1 (Pecanex homolog),Pecanex-like protein 1 (Pecanex homolog protein 1),GO:0016021,integral to membrane,PF05041;,1.00E-108,CHOYP_PCX1.1.1,,,,,,,PCX1_HUMAN,Homo sapiens (Human), comp61055_c0_seq1,387,49.0956,0.51613248,14,23,,4.00E-09,O35646,Calpain-6,Calpain-6,GO:0004198; GO:0005874; GO:0008017; GO:0001578; GO:0048471; GO:0006508; GO:0051493; GO:0005876,calcium-dependent cysteine-type endopeptidase activity; microtubule; microtubule binding; microtubule bundle formation; perinuclear region of cytoplasm; proteolysis; regulation of cytoskeleton organization; spindle microtubule,PF00168;PF01067;PF00648;,,,,,,,,,CAN6_MOUSE,Mus musculus (Mouse),microtubule bundle formation [GO:0001578]; proteolysis [GO:0006508]; regulation of cytoskeleton organization [GO:0051493] comp61058_c0_seq1,536,41.791,0.30442283,15,38,,6.00E-54,B3DLH6,Myoferlin (Fer-1-like protein 3),Myoferlin (Fer-1-like protein 3),GO:0005901; GO:0030659; GO:0016021; GO:0031965; GO:0005543; GO:0001778,caveola; cytoplasmic vesicle membrane; integral to membrane; nuclear membrane; phospholipid binding; plasma membrane repair,PF00168;PF08165;PF08150;PF08151;PF16165;,6.00E-29,CHOYP_MYOF.3.3,,,,,,,MYOF_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778] comp61081_c0_seq1,432,38.1944,0.70292584,9,47,,3.00E-14,P18715,Gastrula zinc finger protein XlCGF26.1 (Fragment),Gastrula zinc finger protein XlCGF26.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG26_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp61081_c1_seq1,493,42.1907,0.82832199,3,46,,4.00E-11,Q9UJQ4,Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4),Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4),GO:0003677; GO:0005737; GO:0030326; GO:0000792; GO:0001833; GO:0046872; GO:0000122; GO:0001843; GO:0005634; GO:0045944; GO:0043234; GO:0019827; GO:0006351; GO:0003281,"DNA binding; cytoplasm; embryonic limb morphogenesis; heterochromatin; inner cell mass cell proliferation; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein complex; stem cell maintenance; transcription, DNA-dependent; ventricular septum development",PF00096;,,,,,,,,,SALL4_HUMAN,Homo sapiens (Human),"embryonic limb morphogenesis [GO:0030326]; inner cell mass cell proliferation [GO:0001833]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281]" comp61104_c0_seq2,260,48.0769,0.47878067,0,13,,3.00E-34,Q9H0R3,Transmembrane protein 222,Transmembrane protein 222,GO:0016021,integral to membrane,PF05608;,8.00E-42,CHOYP_TM222.1.1,,,,,,,TM222_HUMAN,Homo sapiens (Human), comp61108_c0_seq1,292,42.4658,0.30560984,5,25,,5.00E-28,Q5XHB4,Zinc transporter 8 (ZnT-8) (Solute carrier family 30 member 8),Zinc transporter 8 (ZnT-8) (Solute carrier family 30 member 8),GO:0008324; GO:0016021; GO:0005886; GO:0030658; GO:0006829,cation transmembrane transporter activity; integral to membrane; plasma membrane; transport vesicle membrane; zinc ion transport,PF01545;,5.00E-26,CHOYP_LOC100178917.1.1,,,,,,,ZNT8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),insulin secretion [GO:0030073]; regulation of sequestering of zinc ion [GO:0061088]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043] comp61119_c0_seq1,492,32.5203,0.54133557,9,18,,,,,,,,,,,6.00E-178,ruditapes_c1099,,,,,,, comp61121_c0_seq1,428,42.2897,0.53962559,16,6,,5.00E-54,Q9Z280,Phospholipase D1 (PLD 1) (mPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),Phospholipase D1 (PLD 1) (mPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1),GO:0005794; GO:0000139; GO:0070290; GO:0007154; GO:0050830; GO:0005789; GO:0005768; GO:0031902; GO:0016042; GO:0048471; GO:0006654; GO:0035091; GO:0004630,Golgi apparatus; Golgi membrane; NAPE-specific phospholipase D activity; cell communication; defense response to Gram-positive bacterium; endoplasmic reticulum membrane; endosome; late endosome membrane; lipid catabolic process; perinuclear region of cytoplasm; phosphatidic acid biosynthetic process; phosphatidylinositol binding; phospholipase D activity,PF00169;PF00614;PF13091;PF00787;,5.00E-28,CHOYP_PLD1.1.1,,,,,,,PLD1_MOUSE,Mus musculus (Mouse),cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylglycerol biosynthetic process [GO:0006655]; phospholipid biosynthetic process [GO:0008654]; regulation of cell migration [GO:0030334]; regulation of microvillus assembly [GO:0032534]; regulation of phagocytosis [GO:0050764] comp61139_c0_seq1,691,39.0738,0.19290852,15,9,,3.00E-68,O75691,Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6),Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6),GO:0030686; GO:0005737; GO:0000480; GO:0000447; GO:0000472; GO:0008285; GO:0005730; GO:0005654; GO:0030688; GO:0032040,"90S preribosome; cytoplasm; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of cell proliferation; nucleolus; nucleoplasm; preribosome, small subunit precursor; small-subunit processome",PF07539;,,,,,,,,,UTP20_HUMAN,Homo sapiens (Human),"endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of cell proliferation [GO:0008285]; rRNA processing [GO:0006364]" comp61151_c0_seq1,236,38.1356,1.52830125,0,8,,5.00E-10,P34147,Rho-related protein racA,Rho-related protein racA,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00651;PF00071;,,,,,,,,,RACA_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp61186_c0_seq1,326,43.5583,0.84935864,10,16,,4.00E-15,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,5.00E-14,CHOYP_LOC100369716.1.1,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp61228_c0_seq1,348,45.6897,0.94716619,10,0,,2.00E-07,Q8JIS3,D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),GO:0042732; GO:0050038; GO:0005737; GO:0047880,D-xylose metabolic process; L-xylulose reductase (NADP+) activity; cytoplasm; erythrulose reductase activity,,,,,,,,,,DER_CHICK,Gallus gallus (Chicken),D-xylose metabolic process [GO:0042732] comp61242_c0_seq1,211,47.3934,0.76444025,3,5,,1.00E-24,Q5RGJ8,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0030154; GO:0016021; GO:0005634,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; cell differentiation; integral to membrane; nucleus,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,2.00E-30,CHOYP_GNPTA.2.3,,,,,,,GNPTA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256] comp6126_c0_seq1,345,47.2464,0.3131248,6,2,,3.00E-46,A4D161,Protein FAM221A,Protein FAM221A,,,PF14753;,1.00E-48,CHOYP_BRAFLDRAFT_239751.3.3,,,,,,,F221A_HUMAN,Homo sapiens (Human), comp61278_c0_seq1,271,48.3395,0.634337,9,4,,3.00E-10,Q13886,Krueppel-like factor 9 (Basic transcription element-binding protein 1) (BTE-binding protein 1) (GC-box-binding protein 1) (Transcription factor BTEB1),Krueppel-like factor 9 (Basic transcription element-binding protein 1) (BTE-binding protein 1) (GC-box-binding protein 1) (Transcription factor BTEB1),GO:0003677; GO:0097067; GO:0007566; GO:0046872; GO:0005634; GO:0050847; GO:0006357; GO:0003700; GO:0006351,"DNA binding; cellular response to thyroid hormone stimulus; embryo implantation; metal ion binding; nucleus; progesterone receptor signaling pathway; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,,,,,,,,,KLF9_HUMAN,Homo sapiens (Human),"cellular response to cortisol stimulus [GO:0071387]; cellular response to thyroid hormone stimulus [GO:0097067]; circadian rhythm [GO:0007623]; negative regulation of keratinocyte proliferation [GO:0010839]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp61294_c0_seq1,569,42.1793,0.71294779,6,13,,2.00E-09,A6NM28,Zinc finger protein 92 homolog (Zfp-92),Zinc finger protein 92 homolog (Zfp-92),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP92_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp61316_c0_seq1,424,44.3396,0.48895808,0,17,,1.00E-10,Q8BJL1,F-box only protein 30,F-box only protein 30 (Muscle ubiquitin ligase of SCF complex in atrophy-1) (MUSA1),GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,PF15966;PF15965;,,,,,,,,,FBX30_MOUSE,Mus musculus (Mouse), comp61350_c1_seq1,456,47.807,0.85493608,19,0,,2.00E-26,Q761V0,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5),GO:0016021; GO:0005328,integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,9.00E-13,CHOYP_SC6A7.1.1,,,,,,,SC6A5_MOUSE,Mus musculus (Mouse),"glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]" comp61351_c0_seq2,800,41.875,0.45729037,11,0,,,,,,,,,,,2.00E-14,ruditapes_s37379,,,,,,, comp61353_c0_seq1,341,41.6422,0.34255102,12,16,,8.00E-11,Q5RGE5,Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein),Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein),GO:0006310; GO:0006281; GO:0004519; GO:0004527; GO:0090305; GO:0005634,DNA recombination; DNA repair; endonuclease activity; exonuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF07522;PF12706;,,,,,,,,,DCR1C_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848] comp61358_c0_seq1,876,43.0365,0.57664455,53,18,,5.00E-80,Q5ZM45,Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48),Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48),GO:0008234; GO:0005737; GO:0005634; GO:0004221; GO:0006511,cysteine-type peptidase activity; cytoplasm; nucleus; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00240;PF00443;,,,,,,,,,UBP48_CHICK,Gallus gallus (Chicken),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp61443_c0_seq1,342,50.5848,0.32332622,11,5,,1.00E-08,Q80T14,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_MOUSE,Mus musculus (Mouse),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp6148_c0_seq1,291,36.0825,0.10618307,7,0,,,,,,,,,6.00E-19,CHOYP_LOC100877335.1.1,,,,,,,,, comp61495_c0_seq1,282,35.461,0.33974017,6,17,,6.00E-07,Q9PVG3,RE1-silencing transcription factor B (Neural-restrictive silencer factor B) (Fragment),RE1-silencing transcription factor B (Neural-restrictive silencer factor B) (Fragment),GO:0046872; GO:0050768; GO:0045665; GO:0003676; GO:0005634; GO:0043065; GO:0000981; GO:0006366,metal ion binding; negative regulation of neurogenesis; negative regulation of neuron differentiation; nucleic acid binding; nucleus; positive regulation of apoptotic process; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter,,,,,,,,,,RESTB_XENLA,Xenopus laevis (African clawed frog),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp61514_c0_seq2,329,39.8176,0.39118427,2,3,,6.00E-31,Q9UBH6,Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor),Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor),GO:0004930; GO:0005887; GO:0001618,G-protein coupled receptor activity; integral to plasma membrane; virus receptor activity,PF03124;PF03105;,6.00E-45,CHOYP_LOC101159134.1.1,,,,,,,XPR1_HUMAN,Homo sapiens (Human),cellular phosphate ion homeostasis [GO:0030643]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; response to virus [GO:0009615] comp61527_c0_seq1,465,39.7849,0.76898045,16,29,,9.00E-10,Q8K1N1,Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8),Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8),GO:0000139; GO:0019369; GO:0050482; GO:0047499; GO:0008219; GO:0005789; GO:0006631; GO:0016021; GO:0043651; GO:0004622; GO:0048471; GO:0005778; GO:0034638; GO:0046338; GO:0001516,Golgi membrane; arachidonic acid metabolic process; arachidonic acid secretion; calcium-independent phospholipase A2 activity; cell death; endoplasmic reticulum membrane; fatty acid metabolic process; integral to membrane; linoleic acid metabolic process; lysophospholipase activity; perinuclear region of cytoplasm; peroxisomal membrane; phosphatidylcholine catabolic process; phosphatidylethanolamine catabolic process; prostaglandin biosynthetic process,PF01734;,,,,,,,,,PLPL8_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cell death [GO:0008219]; fatty acid metabolic process [GO:0006631]; linoleic acid metabolic process [GO:0043651]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; prostaglandin biosynthetic process [GO:0001516] comp61555_c0_seq1,346,50.8671,0.81170269,17,4,,3.00E-06,Q9Y5P8,Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit),Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit),GO:0000082; GO:0005509; GO:0007050; GO:0005654; GO:0006470; GO:0000159; GO:0008601; GO:0004722,G1/S transition of mitotic cell cycle; calcium ion binding; cell cycle arrest; nucleoplasm; protein dephosphorylation; protein phosphatase type 2A complex; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity,PF13499;,,,,,,,,,P2R3B_HUMAN,Homo sapiens (Human),cell cycle arrest [GO:0007050]; protein dephosphorylation [GO:0006470] comp61570_c0_seq1,413,44.7942,0.50402049,5,12,,1.00E-58,Q5ZI89,Trafficking protein particle complex subunit 11,Trafficking protein particle complex subunit 11,GO:0005794; GO:0016192,Golgi apparatus; vesicle-mediated transport,PF11817;PF12742;,2.00E-78,CHOYP_BRAFLDRAFT_87429.1.1,,,,,,,TPC11_CHICK,Gallus gallus (Chicken),vesicle-mediated transport [GO:0016192] comp61586_c0_seq1,361,61.7729,0.99338938,2,15,,1.00E-07,B1W0K0,Lipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II),Lipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II),GO:0004190; GO:0016021; GO:0005886; GO:0006508,aspartic-type endopeptidase activity; integral to membrane; plasma membrane; proteolysis,PF01252;,,,,,,,,,LSPA_STRGG,Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350), comp61596_c0_seq1,225,40.4444,0.66147648,8,4,,2.00E-07,Q8R422,CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109),CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_MOUSE,Mus musculus (Mouse),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp61602_c0_seq1,298,39.9329,1.3075949,1,0,,2.00E-10,P18433,Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),GO:0007411; GO:0008286; GO:0005887; GO:0006468; GO:0005001,axon guidance; insulin receptor signaling pathway; integral to plasma membrane; protein phosphorylation; transmembrane receptor protein tyrosine phosphatase activity,PF00102;,,,,,,,,,PTPRA_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165] comp61612_c0_seq1,400,44,0.67456426,5,27,,2.00E-37,B2GUN4,Meiosis arrest female protein 1 homolog (Limkain-b1),Meiosis arrest female protein 1 homolog (Limkain-b1),GO:0003723; GO:0000166; GO:0048477; GO:0005777; GO:0010468,RNA binding; nucleotide binding; oogenesis; peroxisome; regulation of gene expression,PF11608;PF01936;PF12872;PF00076;,4.00E-42,CHOYP_MARF1.1.1,,,,,,,MARF1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),meiotic cell cycle [GO:0051321]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] comp61617_c0_seq1,357,37.8151,0.71378495,13,21,,1.00E-11,A6QPM3,Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.43) (PR domain zinc finger protein 6) (PR domain-containing protein 6),Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.43) (PR domain zinc finger protein 6) (PR domain-containing protein 6),GO:0034968; GO:0018024; GO:0046872; GO:0051151; GO:0045892; GO:0022008; GO:0003676; GO:0005634; GO:0006351,"histone lysine methylation; histone-lysine N-methyltransferase activity; metal ion binding; negative regulation of smooth muscle cell differentiation; negative regulation of transcription, DNA-dependent; neurogenesis; nucleic acid binding; nucleus; transcription, DNA-dependent",PF00856;,,,,,,,,,PRDM6_BOVIN,Bos taurus (Bovine),"negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; transcription, DNA-templated [GO:0006351]" comp61627_c0_seq2,425,45.4118,0.73639129,13,12,,4.00E-38,Q8BYI6,Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1),Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1),GO:0003841; GO:0047184; GO:0047192; GO:0000139; GO:0005795; GO:0005509; GO:0005783; GO:0005789; GO:0016021; GO:0005811; GO:0061024; GO:0006663,1-acylglycerol-3-phosphate O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 1-alkylglycerophosphocholine O-acetyltransferase activity; Golgi membrane; Golgi stack; calcium ion binding; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; lipid particle; membrane organization; platelet activating factor biosynthetic process,PF01553;PF13499;,,,,,,,,,PCAT2_MOUSE,Mus musculus (Mouse),membrane organization [GO:0061024]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; platelet activating factor biosynthetic process [GO:0006663] comp6162_c0_seq1,426,43.662,0.49421569,8,5,,3.00E-15,P0C870,JmjC domain-containing protein 7 (Jumonji domain-containing protein 7),JmjC domain-containing protein 7 (Jumonji domain-containing protein 7),,,,6.00E-34,CHOYP_LOC100888222.3.3,,,,,,,JMJD7_HUMAN,Homo sapiens (Human), comp61652_c0_seq2,283,42.7562,0.23640695,2,10,,4.00E-52,O00160,Unconventional myosin-If (Myosin-Ie),Unconventional myosin-If (Myosin-Ie),GO:0005524; GO:0003779; GO:0005516; GO:0030864; GO:0050830; GO:0031941; GO:0003774; GO:0007162; GO:0043312; GO:0030335; GO:0032956; GO:0045088; GO:0016461,ATP binding; actin binding; calmodulin binding; cortical actin cytoskeleton; defense response to Gram-positive bacterium; filamentous actin; motor activity; negative regulation of cell adhesion; neutrophil degranulation; positive regulation of cell migration; regulation of actin cytoskeleton organization; regulation of innate immune response; unconventional myosin complex,PF00063;PF06017;PF14604;,2.00E-68,CHOYP_MYO1E.1.1,,,,,,,MYO1F_HUMAN,Homo sapiens (Human), comp61671_c0_seq1,354,46.8927,0.93860914,2,51,,,,,,,,,3.00E-18,CHOYP_DPER_GL17438.1.1,,,,,,,,, comp61677_c0_seq1,375,38.6667,0.43086632,2,0,,6.00E-13,Q3SYV5,Tetraspanin-33 (Tspan-33),Tetraspanin-33 (Tspan-33),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_BOVIN,Bos taurus (Bovine),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747] comp61677_c0_seq2,305,40,0.50000537,0,7,,2.00E-13,Q86UF1,Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane),Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604] comp61695_c0_seq1,679,45.8027,0.70364391,32,32,,3.00E-84,P31596,Excitatory amino acid transporter 2 (GLT-1) (Sodium-dependent glutamate/aspartate transporter 2) (GLUT-R) (Solute carrier family 1 member 2),Excitatory amino acid transporter 2 (GLT-1) (Sodium-dependent glutamate/aspartate transporter 2) (GLUT-R) (Solute carrier family 1 member 2),GO:0043198; GO:0043197; GO:0005314; GO:0016021; GO:0006836; GO:0042734; GO:0017153,dendritic shaft; dendritic spine; high-affinity glutamate transmembrane transporter activity; integral to membrane; neurotransmitter transport; presynaptic membrane; sodium:dicarboxylate symporter activity,PF00375;,3.00E-40,CHOYP_TBB4B.3.7,2.00E-15,ruditapes_c22391,,,,,EAA2_RAT,Rattus norvegicus (Rat),L-glutamate transport [GO:0015813]; neurotransmitter transport [GO:0006836] comp61718_c0_seq1,429,44.9883,0.46177227,19,15,,5.00E-32,P35234,Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP),Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP),GO:0005737; GO:0035335; GO:0004725,cytoplasm; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00102;,2.00E-59,CHOYP_LOC100374454.1.1,,,,,,,PTN5_RAT,Rattus norvegicus (Rat),"exploration behavior [GO:0035640]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein import into nucleus, translocation [GO:0033160]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of receptor internalization [GO:0002092]; positive regulation of response to drug [GO:2001025]; response to acetylsalicylate [GO:1903492]; response to amphetamine [GO:0001975]; response to drug [GO:0042493]; response to immobilization stress [GO:0035902]" comp61748_c0_seq1,829,41.737,0.41604071,70,19,,4.00E-61,Q5VYK3,Proteasome-associated protein ECM29 homolog (Ecm29),Proteasome-associated protein ECM29 homolog (Ecm29),GO:0030134; GO:0030433; GO:0005813; GO:0005769; GO:0030139; GO:0005783; GO:0005793; GO:0005771; GO:0005634; GO:0000502,ER to Golgi transport vesicle; ER-associated protein catabolic process; centrosome; early endosome; endocytic vesicle; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; multivesicular body; nucleus; proteasome complex,PF13001;PF12755;,2.00E-37,CHOYP_ECM29.1.1,,,,,,,ECM29_HUMAN,Homo sapiens (Human),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; proteasome assembly [GO:0043248] comp61765_c1_seq1,258,44.9612,0.82511593,4,11,,,,,,,,,5.00E-19,CHOYP_LOC100377077.1.1,,,,,,,,, comp61778_c0_seq1,457,38.7309,0.43500887,14,5,,,,,,,,,4.00E-24,CHOYP_LOC100377077.1.1,,,,,,,,, comp61785_c0_seq1,262,43.8931,0.65423839,2,19,,4.00E-27,Q91ZT9,Ankyrin repeat and SOCS box protein 8 (ASB-8),Ankyrin repeat and SOCS box protein 8 (ASB-8),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF12796;PF07525;,2.00E-11,CHOYP_LOC100703270.1.1,,,,,,,ASB8_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] comp61786_c0_seq1,593,40.8094,0.36717137,17,33,,9.00E-83,Q86YQ8,Copine-8 (Copine VIII),Copine-8 (Copine VIII),,,PF00168;PF07002;,1.00E-94,CHOYP_CPNE8.1.2,2.00E-134,ruditapes_c6973,,,,,CPNE8_HUMAN,Homo sapiens (Human), comp61800_c0_seq1,271,43.1734,0.47692058,8,29,,1.00E-12,Q6NU27,Eukaryotic translation initiation factor 4E type 3-B (eIF-4E type 3-B) (eIF-4E3-B) (eIF4E type 3-B) (eIF4E-3-B),Eukaryotic translation initiation factor 4E type 3-B (eIF-4E type 3-B) (eIF-4E3-B) (eIF4E type 3-B) (eIF4E-3-B),GO:0005737; GO:0005845; GO:0006417; GO:0003743,cytoplasm; mRNA cap binding complex; regulation of translation; translation initiation factor activity,PF01652;,3.00E-15,CHOYP_LOC100370061.1.1,,,,,,,I4E3B_XENLA,Xenopus laevis (African clawed frog),regulation of translation [GO:0006417] comp61832_c1_seq1,293,38.2253,1.03126201,16,18,,3.00E-08,Q8BND4,Protein DDX26B,Integrator complex subunit 6-like (Protein DDX26B),,,PF15300;PF13519;,,,,,,,,,DX26B_MOUSE,Mus musculus (Mouse), comp61834_c1_seq1,324,41.0494,0.81621782,4,31,,6.00E-11,Q99MK9,Ras association domain-containing protein 1 (Protein 123F2),Ras association domain-containing protein 1 (Protein 123F2),GO:0007265; GO:0007050; GO:0005737; GO:0046872; GO:0005874; GO:0015630; GO:0005815; GO:0071157; GO:0005634; GO:0005886; GO:0031398; GO:0050821; GO:0006974; GO:0000922,Ras protein signal transduction; cell cycle arrest; cytoplasm; metal ion binding; microtubule; microtubule cytoskeleton; microtubule organizing center; negative regulation of cell cycle arrest; nucleus; plasma membrane; positive regulation of protein ubiquitination; protein stabilization; response to DNA damage stimulus; spindle pole,PF00130;PF16517;PF00788;,,,,,,,,,RASF1_MOUSE,Mus musculus (Mouse),cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of protein ubiquitination [GO:0031398]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265] comp61882_c1_seq1,342,64.6199,0.92794694,0,17,,3.00E-60,Q6A6V2,tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.-) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD) (tRNA threonylcarbamoyladenosine biosynthesis protein TsaD),tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD) (tRNA threonylcarbamoyladenosine biosynthesis protein TsaD),GO:0005737; GO:0005506; GO:0004222; GO:0070526; GO:0016747,"cytoplasm; iron ion binding; metalloendopeptidase activity; threonylcarbamoyladenosine biosynthetic process; transferase activity, transferring acyl groups other than amino-acyl groups",PF00814;,,,,,,,,,GCP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),tRNA threonylcarbamoyladenosine modification [GO:0002949] comp61934_c0_seq1,360,37.7778,0.31563085,1,45,,4.00E-11,Q8IYB9,Zinc finger protein 595,Zinc finger protein 595,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN595_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp61935_c1_seq1,233,43.7768,0.46429427,1,9,,9.00E-24,A4IHM6,Rab-like protein 3,Rab-like protein 3,GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF08477;,4.00E-26,CHOYP_LOC587439.1.1,,,,,,,RABL3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),small GTPase mediated signal transduction [GO:0007264] comp61939_c0_seq1,628,43.7898,0.43610777,14,29,,9.00E-61,Q5R4G0,Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),GO:0006915; GO:0016831; GO:0019752; GO:0005789; GO:0016021; GO:0030170; GO:0008117; GO:0006665,apoptotic process; carboxy-lyase activity; carboxylic acid metabolic process; endoplasmic reticulum membrane; integral to membrane; pyridoxal phosphate binding; sphinganine-1-phosphate aldolase activity; sphingolipid metabolic process,PF00282;,1.00E-13,CHOYP_SGPL1.1.1,,,,,,,SGPL1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),apoptotic process [GO:0006915]; fatty acid metabolic process [GO:0006631]; sphingolipid catabolic process [GO:0030149] comp61966_c0_seq1,412,45.3883,0.80590466,4,28,,6.00E-14,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp61986_c0_seq2,230,47.8261,0.76466192,8,0,,,,,,,,,1.00E-32,CHOYP_NCKX6.1.1,,,,,,,,, comp61996_c0_seq1,239,46.0251,0.07936647,2,17,,3.00E-13,Q08CZ0,Ubiquitin-protein ligase E3B (EC 6.3.2.-),Ubiquitin-protein ligase E3B (EC 6.3.2.-),GO:0004842,ubiquitin-protein ligase activity,PF00632;PF00612;,6.00E-37,CHOYP_LOC659339.2.2,,,,,,,UBE3B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp62019_c0_seq1,216,75,1.00760556,0,21,,5.00E-09,Q9I2A8,Acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase),Acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase),GO:0008137; GO:0003985; GO:0044255; GO:0005737; GO:0006631,NADH dehydrogenase (ubiquinone) activity; acetyl-CoA C-acetyltransferase activity; cellular lipid metabolic process; cytoplasm; fatty acid metabolic process,PF02803;PF00108;,,,,,,,,,ATOB_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),fatty acid metabolic process [GO:0006631] comp62044_c0_seq1,335,60,1.06519673,0,28,,2.00E-10,Q3SL03,Transaldolase (EC 2.2.1.2),Transaldolase (EC 2.2.1.2),GO:0005737; GO:0006098; GO:0004801,cytoplasm; pentose-phosphate shunt; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity,PF00923;,,,,,,,,,TAL_THIDA,Thiobacillus denitrificans (strain ATCC 25259),carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098] comp62049_c0_seq1,249,41.7671,0.27747395,0,0,,5.00E-11,Q6NU98,Serine/threonine-protein kinase pdik1l-B (EC 2.7.11.1),Serine/threonine-protein kinase pdik1l-B (EC 2.7.11.1),GO:0005524; GO:0005634; GO:0004674,ATP binding; nucleus; protein serine/threonine kinase activity,PF00069;,,,,,,,,,PDK1B_XENLA,Xenopus laevis (African clawed frog), comp62049_c0_seq2,345,39.7101,0.3687158,3,5,,1.00E-47,Q5ZJH6,Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3),Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3),GO:0005524; GO:0006914; GO:0005737; GO:0045879; GO:0045880; GO:0046777; GO:0004674,ATP binding; autophagy; cytoplasm; negative regulation of smoothened signaling pathway; positive regulation of smoothened signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity,PF04212;PF00069;,1.00E-34,CHOYP_BRAFLDRAFT_110776.1.1,,,,,,,ULK3_CHICK,Gallus gallus (Chicken),autophagy [GO:0006914]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777] comp62056_c0_seq1,312,41.9872,0.29472996,0,33,,4.00E-07,Q9Y5H1,Protocadherin gamma-A2 (PCDH-gamma-A2),Protocadherin gamma-A2 (PCDH-gamma-A2),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG2_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp62059_c0_seq1,287,45.993,0.79504071,2,0,,,,,,,,,4.00E-27,CHOYP_LOC100374249.1.1,,,,,,,,, comp62090_c0_seq1,446,46.1883,0.54857257,9,9,,7.00E-28,Q14185,Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180),GO:0038096; GO:0005096; GO:0006915; GO:0007411; GO:0007596; GO:0016477; GO:0005829; GO:0005085; GO:0045087; GO:0007229; GO:0016020; GO:0006911; GO:0007264,"Fc-gamma receptor signaling pathway involved in phagocytosis; GTPase activator activity; apoptotic process; axon guidance; blood coagulation; cell migration; cytosol; guanyl-nucleotide exchange factor activity; innate immune response; integrin-mediated signaling pathway; membrane; phagocytosis, engulfment; small GTPase mediated signal transduction",PF06920;PF14429;PF16172;PF14604;,,,,,,,,,DOCK1_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]" comp62091_c0_seq1,524,47.9008,0.67838469,3,16,,2.00E-15,P48766,Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1),Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1),GO:0030315; GO:0030018; GO:1901660; GO:0055074; GO:0070509; GO:0006816; GO:0005432; GO:0007154; GO:0034614; GO:0005887; GO:0014704; GO:0046872; GO:0002026; GO:0055119; GO:0071436; GO:0097369,T-tubule; Z disc; calcium ion export; calcium ion homeostasis; calcium ion import; calcium ion transport; calcium:sodium antiporter activity; cell communication; cellular response to reactive oxygen species; integral to plasma membrane; intercalated disc; metal ion binding; regulation of the force of heart contraction; relaxation of cardiac muscle; sodium ion export; sodium ion import,PF03160;PF01699;PF16494;,,,,,,,,,NAC1_CAVPO,Cavia porcellus (Guinea pig),calcium ion homeostasis [GO:0055074]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell communication [GO:0007154]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; sodium ion transmembrane transport [GO:0035725] comp62091_c0_seq2,283,47.3498,0.65741562,2,0,,3.00E-11,P48767,Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1),Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1),GO:0005432; GO:0007154; GO:0016021; GO:0046872; GO:0005886,calcium:sodium antiporter activity; cell communication; integral to membrane; metal ion binding; plasma membrane,PF03160;PF01699;PF16494;,,,,,,,,,NAC1_FELCA,Felis catus (Cat) (Felis silvestris catus),calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; sodium ion transmembrane transport [GO:0035725] comp62093_c0_seq1,215,48.3721,0.88691728,0,17,,7.00E-10,P29074,Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),GO:0005737; GO:0005856; GO:0009898; GO:0004726,cytoplasm; cytoskeleton; internal side of plasma membrane; non-membrane spanning protein tyrosine phosphatase activity,PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;,,,,,,,,,PTN4_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470] comp62165_c0_seq1,587,37.4787,0.77984311,25,14,,1.00E-28,Q5RD86,DET1- and DDB1-associated protein 1,DET1- and DDB1-associated protein 1,,,PF10172;,3.00E-32,CHOYP_LOC100636433.3.4,,,,,,,DDA1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp62248_c0_seq1,597,41.876,0.46115418,10,52,,3.00E-24,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,2.00E-79,CHOYP_LOC100377364.2.2,,,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp62266_c0_seq1,388,47.1649,0.83162021,14,6,,2.00E-37,P04069,Carboxypeptidase B (EC 3.4.17.2),Carboxypeptidase B (EC 3.4.17.2),GO:0005576; GO:0004181; GO:0006508; GO:0008270,extracellular region; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;,1.00E-42,CHOYP_LOC590567.1.1,4.00E-58,ruditapes_c1317,,,,,CBPB_ASTFL,Astacus astacus (Noble crayfish) (Astacus fluviatilis), comp62310_c0_seq1,344,43.314,0.32717204,9,13,,5.00E-11,Q9XYM0,Adapter molecule Crk,Adapter molecule Crk,GO:0005070; GO:0007298; GO:0048013; GO:0046529; GO:0007520; GO:0046330; GO:0032319; GO:0032956,"SH3/SH2 adaptor activity; border follicle cell migration; ephrin receptor signaling pathway; imaginal disc fusion, thorax closure; myoblast fusion; positive regulation of JNK cascade; regulation of Rho GTPase activity; regulation of actin cytoskeleton organization",PF00017;PF00018;PF07653;,2.00E-33,CHOYP_TPC2.1.2,,,,,,,CRK_DROME,Drosophila melanogaster (Fruit fly),"border follicle cell migration [GO:0007298]; ephrin receptor signaling pathway [GO:0048013]; imaginal disc fusion, thorax closure [GO:0046529]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of JNK cascade [GO:0046330]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]" comp62324_c0_seq1,372,47.043,0.77972866,5,29,,1.00E-05,Q91ZI0,Cadherin EGF LAG seven-pass G-type receptor 3,Cadherin EGF LAG seven-pass G-type receptor 3,GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_MOUSE,Mus musculus (Mouse),axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp62326_c0_seq1,243,39.9177,0.32649973,4,10,,9.00E-23,Q7ZYA0,LMBR1 domain-containing protein 2,LMBR1 domain-containing protein 2,GO:0016021,integral to membrane,PF04791;,1.00E-19,CHOYP_LMBD2.1.1,,,,,,,LMBD2_XENLA,Xenopus laevis (African clawed frog), comp62332_c0_seq1,662,39.7281,0.5212276,20,33,,1.00E-119,Q4KMP7,TBC1 domain family member 10B (Rab27A-GAP-beta),TBC1 domain family member 10B (Rab27A-GAP-beta),GO:0005097; GO:0005737,Rab GTPase activator activity; cytoplasm,PF00566;,5.00E-113,CHOYP_BRAFLDRAFT_84319.1.1,1.00E-22,ruditapes_c19256,,,,,TB10B_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]" comp62333_c0_seq1,327,49.5413,0.55126566,10,6,,9.00E-26,A0JM13,C2 domain-containing protein 3,C2 domain-containing protein 3,GO:0005814; GO:0005929; GO:0005932; GO:0035058,centriole; cilium; microtubule basal body; nonmotile primary cilium assembly,PF00168;,,,,,,,,,C2CD3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),centriole elongation [GO:0061511]; nonmotile primary cilium assembly [GO:0035058]; protein localization to centrosome [GO:0071539] comp62364_c0_seq1,356,27.2472,0.63693634,4,20,,2.00E-12,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,1.00E-22,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp62372_c0_seq1,234,40.5983,0.41667428,6,11,,2.00E-09,P49842,Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1),Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1),GO:0005524; GO:0005634; GO:0004674,ATP binding; nucleus; protein serine/threonine kinase activity,PF10494;,,,,,,,,,STK19_HUMAN,Homo sapiens (Human),protein phosphorylation [GO:0006468] comp62394_c0_seq1,224,38.8393,0.52632628,0,7,,3.00E-07,Q5F4C0,Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1),Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1),GO:0016021; GO:0009268; GO:0010043; GO:0030171,integral to membrane; response to pH; response to zinc ion; voltage-gated proton channel activity,PF00520;PF16799;,2.00E-24,CHOYP_NEMVEDRAFT_V1G246569.1.1,,,,,,,HVCN1_CHICK,Gallus gallus (Chicken),cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transport [GO:0015992]; response to pH [GO:0009268]; response to zinc ion [GO:0010043] comp62406_c0_seq1,754,41.9098,0.52430648,12,87,,4.00E-89,Q6DCQ8,Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta),Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta),GO:0004430; GO:0005524; GO:0005737; GO:0016020,1-phosphatidylinositol 4-kinase activity; ATP binding; cytoplasm; membrane,PF00454;,8.00E-92,CHOYP_LOC655570.2.2,,,,,,,P4K2B_XENLA,Xenopus laevis (African clawed frog), comp62422_c0_seq1,241,57.2614,1.18181835,2,5,,7.00E-06,P69828,Galactitol-specific phosphotransferase enzyme IIA component (EC 2.7.1.-) (EIIA-Gat) (PTS system galactitol-specific EIIA component),PTS system galactitol-specific EIIA component (EIIB-Gat) (Galactitol-specific phosphotransferase enzyme IIA component) (EC 2.7.1.200),GO:0005737; GO:0019402; GO:0016301; GO:0009401; GO:0005215,cytoplasm; galactitol metabolic process; kinase activity; phosphoenolpyruvate-dependent sugar phosphotransferase system; transporter activity,PF00359;,,,,,,,,,PTKA_ECOLI,Escherichia coli (strain K12),galactitol metabolic process [GO:0019402]; galactitol transport [GO:0015796]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401] comp62447_c0_seq1,873,47.4227,0.37350476,37,17,,7.00E-15,Q9BVV6,Protein TALPID3,Protein TALPID3,GO:0005813; GO:0060271; GO:0005737; GO:0007224,centrosome; cilium morphogenesis; cytoplasm; smoothened signaling pathway,PF15324;,,,,,,,,,K0586_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of establishment of protein localization [GO:0070201]; smoothened signaling pathway [GO:0007224] comp62468_c0_seq1,727,45.2545,0.49523903,36,15,,6.00E-08,Q9DE14,Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein),GO:0005524; GO:0003677; GO:0006281; GO:0005634; GO:0018105; GO:0004674,ATP binding; DNA binding; DNA repair; nucleus; peptidyl-serine phosphorylation; protein serine/threonine kinase activity,PF02259;PF02260;PF00454;PF08064;,,,,,,,,,ATR_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105] comp62471_c0_seq1,336,36.9048,0.44577114,7,21,,1.00E-18,Q6GQB9,"ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)","ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)",GO:0005509; GO:0005788; GO:0004571; GO:0016020; GO:0006986,"calcium ion binding; endoplasmic reticulum lumen; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; membrane; response to unfolded protein",PF01532;PF02225;,2.00E-26,CHOYP_EDEM3.1.1,,,,,,,EDEM3_XENLA,Xenopus laevis (African clawed frog),protein glycosylation [GO:0006486]; response to unfolded protein [GO:0006986] comp62481_c0_seq1,259,43.6293,0.84968587,0,20,,1.00E-14,Q8BNA6,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_MOUSE,Mus musculus (Mouse),cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842] comp62489_c0_seq1,325,40.3077,0.23397351,5,0,,6.00E-09,Q6P1G0,HEAT repeat-containing protein 6,HEAT repeat-containing protein 6,,,PF13251;,,,,,,,,,HEAT6_MOUSE,Mus musculus (Mouse), comp62512_c0_seq1,433,42.9561,0.65240866,20,3,,1.00E-17,Q80V63,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_MOUSE,Mus musculus (Mouse),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp62538_c0_seq1,201,37.8109,0,6,7,,,,,,,,,4.00E-32,CHOYP_LOC100907797.3.4,,,,,,,,, comp62596_c0_seq1,230,41.3043,1.02943122,5,5,,1.00E-09,Q24307,Apoptosis 2 inhibitor (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2) (dIAP2),Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2),GO:0050829; GO:0043066; GO:0043154; GO:0061057; GO:0006964; GO:0033160; GO:0070534; GO:0007423; GO:0008270,"defense response to Gram-negative bacterium; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidoglycan recognition protein signaling pathway; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; positive regulation of protein import into nucleus, translocation; protein K63-linked ubiquitination; sensory organ development; zinc ion binding",PF00653;,,,,,,,,,IAP2_DROME,Drosophila melanogaster (Fruit fly),"defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]" comp62672_c0_seq1,447,44.7427,0.58333625,26,0,,2.00E-46,Q86NP2,Negative elongation factor A,Negative elongation factor A,GO:0032021; GO:0003723; GO:0005694; GO:0007275; GO:0034244; GO:0007070; GO:0006351; GO:0017053,"NELF complex; RNA binding; chromosome; multicellular organismal development; negative regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter during mitosis; transcription, DNA-dependent; transcriptional repressor complex",,,,,,,,,,NELFA_DROME,Drosophila melanogaster (Fruit fly),"multicellular organism development [GO:0007275]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; transcription, DNA-templated [GO:0006351]" comp62675_c0_seq1,289,45.3287,0.55003029,7,4,,2.00E-29,Q22036,Calpain-5 (EC 3.4.22.-) (Sex-determining transformer protein 3),Calpain-5 (EC 3.4.22.-) (Sex-determining transformer protein 3),GO:0004198; GO:0030154; GO:0019099; GO:0042004; GO:0005622; GO:0016020; GO:0031293; GO:0016540; GO:0007548,calcium-dependent cysteine-type endopeptidase activity; cell differentiation; female germ-line sex determination; feminization of hermaphrodite soma; intracellular; membrane; membrane protein intracellular domain proteolysis; protein autoprocessing; sex differentiation,PF01067;PF00648;,2.00E-31,CHOYP_LOC100543709.1.1,,,,,,,CAN5_CAEEL,Caenorhabditis elegans,cell differentiation [GO:0030154]; female germ-line sex determination [GO:0019099]; feminization of hermaphrodite soma [GO:0042004]; hermaphrodite somatic sex determination [GO:0042001]; membrane protein intracellular domain proteolysis [GO:0031293]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sex differentiation [GO:0007548] comp62675_c0_seq2,328,44.2073,0.77809158,8,0,,1.00E-22,Q9VT65,Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2],GO:0007298; GO:0005509; GO:0004198; GO:0005737; GO:0016020; GO:0016540; GO:0006508,border follicle cell migration; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; membrane; protein autoprocessing; proteolysis,PF01067;PF00648;,3.00E-30,CHOYP_LOC101061191.1.1,,,,,,,CANB_DROME,Drosophila melanogaster (Fruit fly),border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233] comp62690_c0_seq1,1179,43.5963,0.51888618,47,24,,8.00E-34,Q6AZ28,E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2),GO:0003677; GO:0016605; GO:0019789; GO:0030521; GO:0016607; GO:0005634; GO:0050775; GO:0045893; GO:0016925; GO:0060765; GO:0033574; GO:0007283; GO:0006351; GO:0008270,"DNA binding; PML body; SUMO ligase activity; androgen receptor signaling pathway; nuclear speck; nucleus; positive regulation of dendrite morphogenesis; positive regulation of transcription, DNA-dependent; protein sumoylation; regulation of androgen receptor signaling pathway; response to testosterone stimulus; spermatogenesis; transcription, DNA-dependent; zinc ion binding",PF14324;PF02891;,,,,,,,,,PIAS2_RAT,Rattus norvegicus (Rat),"androgen receptor signaling pathway [GO:0030521]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription, DNA-templated [GO:0045893]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; response to organic substance [GO:0010033]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp62690_c1_seq1,255,41.1765,0.46478565,4,2,,1.00E-09,Q5XIU2,Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor),Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN143_RAT,Rattus norvegicus (Rat),"positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp62691_c0_seq1,253,53.3597,1.00396825,0,19,,4.00E-17,Q6DDK3,Dual oxidase maturation factor 1 (Dual oxidase activator 1),Dual oxidase maturation factor 1 (Dual oxidase activator 1),GO:0005789; GO:0016021; GO:0015031,endoplasmic reticulum membrane; integral to membrane; protein transport,PF10204;,5.00E-19,CHOYP_LOC100367809.1.2,,,,,,,DOXA1_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp62713_c0_seq1,647,37.558,0.40343207,21,38,,1.00E-29,P43403,Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase),Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase),GO:0005524; GO:0042113; GO:0070489; GO:0072678; GO:0042101; GO:0050852; GO:0002250; GO:0043366; GO:0005829; GO:0001772; GO:0007243; GO:0045060; GO:0004715; GO:0045582; GO:0046638; GO:0046641; GO:0050850; GO:0045059; GO:0046777,ATP binding; B cell activation; T cell aggregation; T cell migration; T cell receptor complex; T cell receptor signaling pathway; adaptive immune response; beta selection; cytosol; immunological synapse; intracellular protein kinase cascade; negative thymic T cell selection; non-membrane spanning protein tyrosine kinase activity; positive regulation of T cell differentiation; positive regulation of alpha-beta T cell differentiation; positive regulation of alpha-beta T cell proliferation; positive regulation of calcium-mediated signaling; positive thymic T cell selection; protein autophosphorylation,PF07714;PF00017;,2.00E-36,CHOYP_LOC589201.1.1,,,,,,,ZAP70_HUMAN,Homo sapiens (Human),adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; macrophage activation involved in immune response [GO:0002281]; negative thymic T cell selection [GO:0045060]; neutrophil activation involved in immune response [GO:0002283]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; T cell activation [GO:0042110]; T cell aggregation [GO:0070489]; T cell differentiation [GO:0030217]; T cell migration [GO:0072678]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp62722_c0_seq1,764,47.5131,0.42452903,29,30,,2.00E-95,A7MB45,"Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1)","Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1)",GO:0005524; GO:0003987; GO:0005739,ATP binding; acetate-CoA ligase activity; mitochondrion,PF16177;PF00501;PF13193;,1.00E-71,CHOYP_ACSS3.1.1,,,,,,,ACSS3_BOVIN,Bos taurus (Bovine),metabolic process [GO:0008152] comp62739_c0_seq1,229,66.3755,1.38287341,0,43,,7.00E-06,P55502,Uncharacterized protein y4jB,Uncharacterized protein y4jB,GO:0043565; GO:0004803; GO:0006313,"sequence-specific DNA binding; transposase activity; transposition, DNA-mediated",PF01527;,,,,,,,,,Y4JB_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234),"transposition, DNA-mediated [GO:0006313]" comp62781_c0_seq1,247,45.749,0.23619435,0,24,,2.00E-12,Q9BRR6,ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147) (RbBP-35),ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147) (RbBP-35),GO:0043843; GO:0005576; GO:0006096; GO:0046872,ADP-specific glucokinase activity; extracellular region; glycolysis; metal ion binding,PF04587;,,,,,,,,,ADPGK_HUMAN,Homo sapiens (Human),glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] comp62788_c1_seq1,211,47.3934,0.61349042,1,5,,3.00E-08,Q06561,Basement membrane proteoglycan (Perlecan homolog) (Uncoordinated protein 52) (Protein unc-52),Basement membrane proteoglycan (Perlecan homolog) (Uncoordinated protein 52) (Protein unc-52),GO:0005604; GO:0016477; GO:0009792; GO:0007173; GO:0031581; GO:0048644; GO:0030239; GO:0040017; GO:0005198,basement membrane; cell migration; embryo development ending in birth or egg hatching; epidermal growth factor receptor signaling pathway; hemidesmosome assembly; muscle organ morphogenesis; myofibril assembly; positive regulation of locomotion; structural molecule activity,PF07679;PF13895;PF00052;PF00053;PF00054;PF02210;PF00057;,,,,,,,,,UNC52_CAEEL,Caenorhabditis elegans,cell migration [GO:0016477]; embryo development ending in birth or egg hatching [GO:0009792]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hemidesmosome assembly [GO:0031581]; locomotion [GO:0040011]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; myofibril assembly [GO:0030239]; positive regulation of locomotion [GO:0040017] comp62794_c0_seq1,211,60.6635,1.41441279,2,0,,1.00E-18,A7GMJ3,Lactate utilization protein B,Lactate utilization protein B,GO:0051539; GO:0019516; GO:0046872,"4 iron, 4 sulfur cluster binding; lactate oxidation; metal ion binding",PF02589;PF11870;PF13183;,,,,,,,,,LUTB_BACCN,Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98),lactate oxidation [GO:0019516] comp62829_c0_seq1,250,43.2,1.03863731,1,25,,1.00E-36,Q9V3Z6,Myosin-VIIa (DmVIIa) (Protein crinkled),Myosin-VIIa (DmVIIa) (Protein crinkled),GO:0005524; GO:0003779; GO:0007015; GO:0030048; GO:0030898; GO:0048800; GO:0045179; GO:0008407; GO:0035293; GO:0035317; GO:0008586; GO:0005902; GO:0003774; GO:0031477; GO:0007605,ATP binding; actin binding; actin filament organization; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; apical cortex; chaeta morphogenesis; chitin-based larval cuticle pattern formation; imaginal disc-derived wing hair organization; imaginal disc-derived wing vein morphogenesis; microvillus; motor activity; myosin VII complex; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,7.00E-30,CHOYP_MYO7A.1.3,,,,,,,MYO7A_DROME,Drosophila melanogaster (Fruit fly),actin filament-based movement [GO:0030048]; actin filament organization [GO:0007015]; antennal development [GO:0007469]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; chitin-based larval cuticle pattern formation [GO:0035293]; follicle cell microvillus organization [GO:0032529]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605] comp62871_c0_seq1,215,55.814,0.8692341,3,4,,9.00E-17,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp62872_c0_seq1,577,42.9809,0.65981933,33,7,,3.00E-21,Q9NRA2,Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter),GO:0006865; GO:0030054; GO:0005887; GO:0005765; GO:0015136; GO:0015739; GO:0005351; GO:0030672,amino acid transport; cell junction; integral to plasma membrane; lysosomal membrane; sialic acid transmembrane transporter activity; sialic acid transport; sugar:hydrogen symporter activity; synaptic vesicle membrane,PF07690;,2.00E-15,CHOYP_LOC100378615.2.2,,,,,,,S17A5_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739] comp62873_c0_seq1,388,39.6907,0.19955673,7,19,,,,,,,,,2.00E-13,CHOYP_LOC100373433.1.1,,,,,,,,, comp62957_c0_seq1,459,44.6623,0.79234826,17,16,,1.00E-38,Q9I993,"Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1)","Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1)",GO:0003834; GO:0046872; GO:0004497; GO:0001523; GO:0042572,"beta-carotene 15,15'-monooxygenase activity; metal ion binding; monooxygenase activity; retinoid metabolic process; retinol metabolic process",PF03055;,,,,,,,,,BCDO1_CHICK,Gallus gallus (Chicken),beta-carotene metabolic process [GO:1901810]; response to retinoic acid [GO:0032526]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] comp62963_c0_seq1,556,42.8058,0.52198842,11,30,,8.00E-14,P80108,Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D),GO:0006507; GO:0002042; GO:0071277; GO:0071397; GO:0035690; GO:0071467; GO:0071401; GO:0002062; GO:0002430; GO:0005615; GO:0004621; GO:0097241; GO:0008286; GO:0005765; GO:0008285; GO:0010897; GO:0001503; GO:0046470; GO:0010694; GO:0043065; GO:0045919; GO:0010595; GO:0010907; GO:0010983; GO:0035774; GO:0051044; GO:0010867; GO:0005578; GO:1900076; GO:0009749; GO:0017080; GO:0070633,GPI anchor release; cell migration involved in sprouting angiogenesis; cellular response to calcium ion; cellular response to cholesterol; cellular response to drug; cellular response to pH; cellular response to triglyceride; chondrocyte differentiation; complement receptor mediated signaling pathway; extracellular space; glycosylphosphatidylinositol phospholipase D activity; hematopoietic stem cell migration to bone marrow; insulin receptor signaling pathway; lysosomal membrane; negative regulation of cell proliferation; negative regulation of triglyceride catabolic process; ossification; phosphatidylcholine metabolic process; positive regulation of alkaline phosphatase activity; positive regulation of apoptotic process; positive regulation of cytolysis; positive regulation of endothelial cell migration; positive regulation of glucose metabolic process; positive regulation of high-density lipoprotein particle clearance; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of membrane protein ectodomain proteolysis; positive regulation of triglyceride biosynthetic process; proteinaceous extracellular matrix; regulation of cellular response to insulin stimulus; response to glucose stimulus; sodium channel regulator activity; transepithelial transport,PF01839;PF00882;,,,,,,,,,PHLD_HUMAN,Homo sapiens (Human),cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633] comp62970_c0_seq1,423,47.7541,1.07320636,9,21,,6.00E-39,O75095,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07645;PF00053;,,,,,,,,,MEGF6_HUMAN,Homo sapiens (Human), comp62971_c0_seq1,574,43.2056,0.85757158,1,2,,3.00E-17,Q9PVE8,Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30),Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,C330_FUNHE,Fundulus heteroclitus (Killifish) (Mummichog), comp62971_c0_seq2,496,43.75,0.87887183,0,0,,4.00E-08,P49430,Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1),Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1),GO:0030644; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705; GO:0045907; GO:0001516; GO:0004796,"cellular chloride ion homeostasis; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; positive regulation of vasoconstriction; prostaglandin biosynthetic process; thromboxane-A synthase activity",PF00067;,,,,,,,,,THAS_RAT,Rattus norvegicus (Rat),cellular chloride ion homeostasis [GO:0030644]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542] comp62988_c0_seq1,437,46.2243,0.30562361,35,0,,,,,,,,,6.00E-40,CHOYP_LOC100186692.1.1,,,,,,,,, comp62988_c1_seq1,608,45.0658,0.53046036,44,3,,2.00E-16,P07524,Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase),Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase),GO:0042438; GO:0046872; GO:0004503,melanin biosynthetic process; metal ion binding; monophenol monooxygenase activity,PF00264;,,,,,,,,,TYRO_STRAT,Streptomyces antibioticus,melanin biosynthetic process [GO:0042438] comp63015_c1_seq1,215,43.7209,0.71643341,2,5,,8.00E-35,Q99707,Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),GO:0034641; GO:0031419; GO:0009235; GO:0005829; GO:0008898; GO:0008705; GO:0032259; GO:0007399; GO:0042558; GO:0000096; GO:0006805; GO:0008270,cellular nitrogen compound metabolic process; cobalamin binding; cobalamin metabolic process; cytosol; homocysteine S-methyltransferase activity; methionine synthase activity; methylation; nervous system development; pteridine-containing compound metabolic process; sulfur amino acid metabolic process; xenobiotic metabolic process; zinc ion binding,PF02310;PF02607;PF02965;PF00809;PF02574;,1.00E-38,CHOYP_METH.1.1,,,,,,,METH_HUMAN,Homo sapiens (Human),axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; nervous system development [GO:0007399]; pteridine-containing compound metabolic process [GO:0042558]; response to axon injury [GO:0048678]; sulfur amino acid metabolic process [GO:0000096] comp63063_c1_seq1,382,34.8168,1.00741962,10,4,,4.00E-38,Q9VPF8,Transmembrane protein 104 homolog,Transmembrane protein 104 homolog,GO:0016021,integral to membrane,PF01490;,5.00E-28,CHOYP_BRAFLDRAFT_266463.2.2,,,,,,,TM104_DROME,Drosophila melanogaster (Fruit fly), comp63080_c0_seq1,253,62.4506,1.02157323,4,5,,1.00E-07,P30144,Na(+)-linked D-alanine glycine permease,Na(+)-linked D-alanine glycine permease,GO:0015655; GO:0016021; GO:0005886,alanine:sodium symporter activity; integral to membrane; plasma membrane,PF01235;,,,,,,,,,DAGA_PSEHA,Pseudoalteromonas haloplanktis (Alteromonas haloplanktis), comp63119_c1_seq1,244,43.8525,1.42444253,7,3,,1.00E-30,P05934,Calmodulin (CaM) (Fragment),Calmodulin (CaM) (Fragment),GO:0005509,calcium ion binding,PF13499;,8.00E-29,CHOYP_LOC100533341.1.1,4.00E-31,ruditapes_lrc8201,,,,,CALM_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp63132_c0_seq1,296,40.5405,0.75000856,9,10,,5.00E-37,Q9CXF4,TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),GO:0005097; GO:0005576; GO:0005739,Rab GTPase activator activity; extracellular region; mitochondrion,PF12068;PF00566;,2.00E-43,CHOYP_TBC15.1.1,,,,,,,TBC15_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338] comp63162_c0_seq1,311,39.2283,0,16,17,,7.00E-45,A0JMD2,Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28),Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28),GO:0005829; GO:0031901; GO:0046872; GO:0007175; GO:0032266,cytosol; early endosome membrane; metal ion binding; negative regulation of epidermal growth factor-activated receptor activity; phosphatidylinositol-3-phosphate binding,PF01363;,1.00E-53,CHOYP_LOC100747478.1.1,,,,,,,LST2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059] comp63162_c1_seq1,242,46.281,0.50625864,4,5,,8.00E-30,B0WAQ0,Lateral signaling target protein 2 homolog,Lateral signaling target protein 2 homolog,GO:0046872,metal ion binding,PF01363;,,,,,,,,,LST2_CULQU,Culex quinquefasciatus (Southern house mosquito) (Culex pungens), comp63193_c0_seq3,393,46.5649,0.59772827,2,0,,2.00E-06,Q5VYJ5,MAM and LDL-receptor class A domain-containing protein C10orf112,MAM and LDL-receptor class A domain-containing protein 1,GO:0016021,integral to membrane,PF00008;PF00057;PF00629;,,,,,,,,,CJ112_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] comp63207_c0_seq1,255,43.5294,0.24984119,0,0,,2.00E-08,P51589,Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2),GO:0008405; GO:0008404; GO:0070330; GO:0005789; GO:0019373; GO:0020037; GO:0005506; GO:0071614; GO:0043651; GO:0008016; GO:0006805,"arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; aromatase activity; endoplasmic reticulum membrane; epoxygenase P450 pathway; heme binding; iron ion binding; linoleic acid epoxygenase activity; linoleic acid metabolic process; regulation of heart contraction; xenobiotic metabolic process",PF00067;,,,,,,,,,CP2J2_HUMAN,Homo sapiens (Human),epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805] comp63207_c0_seq2,383,42.5587,0.34688583,8,0,,1.00E-18,Q09660,Probable cytochrome P450 CYP44 (EC 1.14.-.-),Probable cytochrome P450 CYP44 (EC 1.14.-.-),GO:0020037; GO:0005506; GO:0004497; GO:0016705,"heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CC44_CAEEL,Caenorhabditis elegans, comp63208_c0_seq1,221,62.4434,1.10593557,0,10,,4.00E-09,O84832,DNA recombination protein RmuC homolog,DNA recombination protein RmuC homolog,GO:0006310,DNA recombination,PF02646;,,,,,,,,,RMUC_CHLTR,Chlamydia trachomatis (strain D/UW-3/Cx),DNA recombination [GO:0006310] comp63223_c0_seq1,203,39.9015,0.49757305,2,8,,2.00E-10,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,,,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp63223_c0_seq2,228,42.1053,0.39913622,0,10,,5.00E-08,Q8N972,Zinc finger protein 709,Zinc finger protein 709,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN709_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp63230_c0_seq1,221,61.086,1.15418276,4,17,,6.00E-08,O50453,Trehalose transport system permease protein SugB,,GO:0008643; GO:0044117; GO:0016021; GO:0005886; GO:0005215,carbohydrate transport; growth of symbiont in host; integral to membrane; plasma membrane; transporter activity,,,,,,,,,,SUGB_MYCTU,, comp63251_c0_seq1,203,42.3645,1.01271073,1,0,,1.00E-12,Q92485,Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-),GO:0005615; GO:0016798; GO:0006685; GO:0004767,"extracellular space; hydrolase activity, acting on glycosyl bonds; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity",PF00149;,,,,,,,,,ASM3B_HUMAN,Homo sapiens (Human),inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] comp63282_c0_seq1,268,69.7761,0.99103383,0,26,,7.00E-06,P49309,Probable rhizopine catabolism regulatory protein MocR,Probable rhizopine catabolism regulatory protein MocR,GO:0003677; GO:0030170; GO:0003700; GO:0008483; GO:0006351,"DNA binding; pyridoxal phosphate binding; sequence-specific DNA binding transcription factor activity; transaminase activity; transcription, DNA-dependent",PF00155;PF00392;,,,,,,,,,MOCR_RHIML,Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti),"transcription, DNA-templated [GO:0006351]" comp63311_c0_seq1,416,45.4327,0.60746653,4,16,,9.00E-42,P07872,"Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain]","Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain]",GO:0003995; GO:0033540; GO:0005504; GO:0050660; GO:0006091; GO:0016401; GO:0005777; GO:0006693,acyl-CoA dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid binding; flavin adenine dinucleotide binding; generation of precursor metabolites and energy; palmitoyl-CoA oxidase activity; peroxisome; prostaglandin metabolic process,PF01756;PF02770;PF14749;,2.00E-27,CHOYP_BRAFLDRAFT_278832.1.1,,,,,,,ACOX1_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693] comp63327_c0_seq1,719,38.3866,0.89224311,21,30,,3.00E-17,P18749,Oocyte zinc finger protein XlCOF6 (Fragment),Oocyte zinc finger protein XlCOF6 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZO6_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp63337_c0_seq1,228,40.7895,0.88078617,3,11,,4.00E-22,Q9WU06,Advillin (Peripheral nervous system villin-like protein) (Pervin),Advillin (Peripheral nervous system villin-like protein) (Pervin),GO:0003779; GO:0051693; GO:0030424; GO:0060271; GO:0005737; GO:0005856; GO:0007010; GO:0043005; GO:0010976,actin binding; actin filament capping; axon; cilium morphogenesis; cytoplasm; cytoskeleton; cytoskeleton organization; neuron projection; positive regulation of neuron projection development,PF00626;PF02209;,1.00E-14,CHOYP_LOC100369378.1.1,,,,,,,AVIL_RAT,Rattus norvegicus (Rat),actin filament capping [GO:0051693]; cilium morphogenesis [GO:0060271]; cytoskeleton organization [GO:0007010]; nervous system development [GO:0007399]; positive regulation of neuron projection development [GO:0010976] comp63358_c0_seq1,203,39.4089,1.02258121,8,13,,8.00E-10,Q24306,Apoptosis 1 inhibitor (EC 6.3.2.-) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (dIAP1) (Protein thread),Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread),GO:0019788; GO:0016055; GO:0048800; GO:0007298; GO:0008407; GO:0004869; GO:0005737; GO:0008354; GO:0097340; GO:1990001; GO:0043066; GO:0046673; GO:0005634; GO:0090263; GO:0031398; GO:0042787; GO:0045035; GO:0007289; GO:0004842; GO:0008270,NEDD8 ligase activity; Wnt receptor signaling pathway; antennal morphogenesis; border follicle cell migration; chaeta morphogenesis; cysteine-type endopeptidase inhibitor activity; cytoplasm; germ cell migration; inhibition of cysteine-type endopeptidase activity; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of compound eye retinal cell programmed cell death; nucleus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sensory organ precursor cell division; spermatid nucleus differentiation; ubiquitin-protein ligase activity; zinc ion binding,PF00653;,,,5.00E-16,ruditapes2_c1114,,,,,IAP1_DROME,Drosophila melanogaster (Fruit fly),antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055] comp63401_c0_seq1,305,46.8852,0.48284543,6,0,,6.00E-22,Q8BUZ3,Tigger transposable element-derived protein 4,Tigger transposable element-derived protein 4,GO:0003677; GO:0005634,DNA binding; nucleus,PF04218;PF03184;PF03221;,,,,,,,,,TIGD4_MOUSE,Mus musculus (Mouse), comp63430_c0_seq1,441,42.6304,0.31028591,15,3,,1.00E-45,Q6PB70,Anoctamin-8 (Transmembrane protein 16H),Anoctamin-8 (Transmembrane protein 16H),GO:0016021; GO:0005622; GO:0005886,integral to membrane; intracellular; plasma membrane,PF04547;,,,,,,,,,ANO8_MOUSE,Mus musculus (Mouse),chloride transport [GO:0006821] comp63469_c0_seq1,269,51.6729,1.06212648,0,9,,2.00E-16,P94369,Putative purine-cytosine permease YxlA,Putative purine-cytosine permease YxlA,GO:0016021; GO:0015205; GO:0005886,integral to membrane; nucleobase transmembrane transporter activity; plasma membrane,PF02133;,,,,,,,,,YXLA_BACSU,Bacillus subtilis (strain 168),transmembrane transport [GO:0055085] comp63491_c0_seq1,441,47.619,1.02503184,3,63,,8.00E-22,Q61555,Fibrillin-2,Fibrillin-2 [Cleaved into: Fibrillin-2 C-terminal peptide],GO:0060346; GO:0005509; GO:0030326; GO:0005201; GO:0001527; GO:0030501; GO:0045669; GO:0035583,bone trabecula formation; calcium ion binding; embryonic limb morphogenesis; extracellular matrix structural constituent; microfibril; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; sequestering of TGFbeta in extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN2_MOUSE,Mus musculus (Mouse),bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; sequestering of TGFbeta in extracellular matrix [GO:0035583] comp63510_c0_seq1,407,45.4545,0.57223347,19,10,,2.00E-31,Q5F362,Cell cycle control protein 50A (Transmembrane protein 30A),Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A),GO:0016021,integral to membrane,PF03381;,3.00E-12,CHOYP_LOC100646416.1.1,,,,,,,CC50A_CHICK,Gallus gallus (Chicken),phospholipid transport [GO:0015914] comp63557_c0_seq1,351,40.7407,0.21204991,9,9,,5.00E-56,Q6NSI8,Uncharacterized protein KIAA1841,Uncharacterized protein KIAA1841,,,PF11822;,3.00E-62,CHOYP_K1841.1.1,,,,,,,K1841_HUMAN,Homo sapiens (Human), comp63580_c0_seq1,259,39.7683,0.3966497,7,14,,5.00E-20,Q96IK5,Germ cell-less protein-like 1,Germ cell-less protein-like 1,GO:0030154; GO:0007275; GO:0005635; GO:0016363; GO:0006355; GO:0007283,"cell differentiation; multicellular organismal development; nuclear envelope; nuclear matrix; regulation of transcription, DNA-dependent; spermatogenesis",PF07707;PF00651;,,,,,,,,,GMCL1_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]" comp63599_c1_seq1,224,44.1964,0.45956798,1,9,,7.00E-10,P42577,Soma ferritin (EC 1.16.3.1),Soma ferritin (EC 1.16.3.1),GO:0006879; GO:0005737; GO:0008199; GO:0004322; GO:0006826,cellular iron ion homeostasis; cytoplasm; ferric iron binding; ferroxidase activity; iron ion transport,PF00210;,7.00E-36,CHOYP_LOC100881468.1.1,,,,,,,FRIS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] comp63637_c0_seq1,237,32.0675,0.19070852,4,0,,,,,,,,,,,7.00E-59,ruditapes_c22472,,,,,,, comp63657_c0_seq1,210,43.8095,0.50455472,6,18,,7.00E-19,O75581,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0034185; GO:0090245; GO:0060349; GO:0046849; GO:0060444; GO:0061310; GO:0044335; GO:0061324; GO:0044340; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0021987; GO:0060026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0030326; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:0005886; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0045598; GO:0030278; GO:0051593; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; apolipoprotein binding; axis elongation involved in somitogenesis; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; canonical Wnt receptor signaling pathway involved in regulation of cell proliferation; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; cerebral cortex development; convergent extension; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic limb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; plasma membrane; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; regulation of fat cell differentiation; regulation of ossification; response to folic acid; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,1.00E-12,CHOYP_LRP6.3.6,,,,,,,LRP6_HUMAN,Homo sapiens (Human),"axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; single organismal cell-cell adhesion [GO:0016337]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp63736_c0_seq1,292,46.9178,0.74968896,5,17,,8.00E-07,Q7T163,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0016021; GO:0005770; GO:0007399,integral to membrane; late endosome; nervous system development,PF00023;PF12796;PF07693;,,,,,,,,,KDIS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859] comp63773_c0_seq1,530,44.3396,0.76120687,0,8,,8.00E-17,Q8WU39,Marginal zone B- and B1-cell-specific protein (Mesenteric estrogen-dependent adipose 7) (MEDA-7) (Plasma cell-induced resident endoplasmic reticulum protein) (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein),Marginal zone B- and B1-cell-specific protein (Mesenteric estrogen-dependent adipose 7) (MEDA-7) (Plasma cell-induced resident endoplasmic reticulum protein) (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein),GO:0006915; GO:0005737; GO:0034663; GO:0005788; GO:0005576; GO:0033622; GO:2001274; GO:0008284; GO:0002642; GO:0030888,apoptotic process; cytoplasm; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; extracellular region; integrin activation; negative regulation of glucose import in response to insulin stimulus; positive regulation of cell proliferation; positive regulation of immunoglobulin biosynthetic process; regulation of B cell proliferation,PF11938;,,,,,,,,,PERP1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; integrin activation [GO:0033622]; negative regulation of glucose import in response to insulin stimulus [GO:2001274]; positive regulation of cell proliferation [GO:0008284]; positive regulation of immunoglobulin biosynthetic process [GO:0002642]; regulation of B cell proliferation [GO:0030888]; regulation of cell proliferation [GO:0042127] comp63829_c0_seq1,293,38.5666,0.64717735,6,18,,9.00E-21,Q6PBT5,Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-),Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-),GO:0016491,oxidoreductase activity,PF07992;,7.00E-18,CHOYP_PYRD1.1.1,,,,,,,PYRD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp63845_c0_seq1,577,44.1941,0.39285832,0,16,,7.00E-15,Q8NHG8,E3 ubiquitin-protein ligase ZNRF2 (EC 6.3.2.-) (Protein Ells2) (RING finger protein 202) (Zinc/RING finger protein 2),E3 ubiquitin-protein ligase ZNRF2 (EC 6.3.2.-) (Protein Ells2) (RING finger protein 202) (Zinc/RING finger protein 2),GO:0030054; GO:0010008; GO:0016874; GO:0005765; GO:0042734; GO:0016567; GO:0008270,cell junction; endosome membrane; ligase activity; lysosomal membrane; presynaptic membrane; protein ubiquitination; zinc ion binding,PF13639;,,,,,,,,,ZNRF2_HUMAN,Homo sapiens (Human),protein polyubiquitination [GO:0000209] comp63848_c0_seq1,374,41.7112,0.50505412,14,24,,9.00E-26,Q96T23,Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),GO:0034080; GO:0006352; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0005654; GO:0016584; GO:0045893; GO:0050434; GO:0008270,"CENP-A containing nucleosome assembly at centromere; DNA-dependent transcription, initiation; RSF complex; histone binding; negative regulation of DNA binding; negative regulation of transcription, DNA-dependent; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; positive regulation of viral transcription; zinc ion binding",PF00628;PF15612;,2.00E-14,CHOYP_SI_DKEY-21N12.1.1.1,,,,,,,RSF1_HUMAN,Homo sapiens (Human),"CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]" comp63884_c0_seq1,235,63.4043,1.31259329,0,14,,4.00E-34,O06465,Alkyl hydroperoxide reductase subunit F (EC 1.8.1.-),Alkyl hydroperoxide reductase subunit F (EC 1.8.1.-),GO:0051287; GO:0008785; GO:0045454; GO:0009055; GO:0050660; GO:0015035; GO:0000302,NAD binding; alkyl hydroperoxide reductase activity; cell redox homeostasis; electron carrier activity; flavin adenine dinucleotide binding; protein disulfide oxidoreductase activity; response to reactive oxygen species,PF07992;PF13192;,,,,,,,,,AHPF_XANCH,Xanthomonas campestris pv. phaseoli,cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302] comp63898_c0_seq1,221,41.1765,0.33980288,1,10,,4.00E-29,Q91YJ2,Sorting nexin-4,Sorting nexin-4,GO:0007154; GO:0005868; GO:0031901; GO:0032456; GO:0035091; GO:0015031,cell communication; cytoplasmic dynein complex; early endosome membrane; endocytic recycling; phosphatidylinositol binding; protein transport,PF00787;,2.00E-36,CHOYP_BRAFLDRAFT_120826.1.1,,,,,,,SNX4_MOUSE,Mus musculus (Mouse),endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; vesicle organization [GO:0016050] comp63918_c0_seq1,353,35.1275,0.20557656,13,15,,9.00E-10,Q24732,Protein glass,Protein glass,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0050896; GO:0006351; GO:0007601,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; response to stimulus; transcription, DNA-dependent; visual perception",PF00096;,,,,,,,,,GLAS_DROVI,Drosophila virilis (Fruit fly),"regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp63919_c0_seq1,721,45.215,0.57472747,28,22,,,,,,,,,2.00E-16,CHOYP_LOC657912.1.1,,,,,,,,, comp63943_c0_seq1,410,58.7805,1.27394338,0,22,,4.00E-57,O53204,Uncharacterized ABC transporter ATP-binding protein Rv2477c/MT2552,,GO:0005524; GO:0006200; GO:0016887; GO:0005618; GO:0005829; GO:0040007; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; cell wall; cytosol; growth; plasma membrane; transport,,,,,,,,,,Y2477_MYCTU,, comp63957_c0_seq1,425,42.3529,0.95623425,15,29,,1.00E-10,Q1RMT8,Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1),Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1),GO:0005524; GO:0001816; GO:0019221; GO:0005737; GO:0045087; GO:0000287; GO:0004674,ATP binding; cytokine production; cytokine-mediated signaling pathway; cytoplasm; innate immune response; magnesium ion binding; protein serine/threonine kinase activity,PF07714;,,,,,,,,,IRAK4_BOVIN,Bos taurus (Bovine),cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp63962_c0_seq1,358,36.8715,0.58347332,3,0,,5.00E-20,P00533,Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1),Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1),GO:0005524; GO:0038095; GO:0000139; GO:0004709; GO:0070435; GO:0051015; GO:0043006; GO:0007202; GO:0007411; GO:0016323; GO:0008283; GO:0016337; GO:0071392; GO:0021795; GO:0003682; GO:0048546; GO:0003690; GO:0001892; GO:0030139; GO:0005789; GO:0005768; GO:0010008; GO:0005006; GO:0005615; GO:0008543; GO:0001942; GO:0045087; GO:0016021; GO:0045121; GO:0060571; GO:0043066; GO:0042059; GO:0042177; GO:0048011; GO:0031965; GO:0005634; GO:0001503; GO:0048471; GO:0048015; GO:0045739; GO:0045740; GO:0070374; GO:0043406; GO:0035413; GO:0030335; GO:0031659; GO:0050679; GO:0048146; GO:0045429; GO:0051897; GO:0045944; GO:0046777; GO:0046982; GO:0051205; GO:0004716; GO:0050999; GO:0050730; GO:0070141; GO:0007435,ATP binding; Fc-epsilon receptor signaling pathway; Golgi membrane; MAP kinase kinase kinase activity; Shc-EGFR complex; actin filament binding; activation of phospholipase A2 activity by calcium-mediated signaling; activation of phospholipase C activity; axon guidance; basolateral plasma membrane; cell proliferation; cell-cell adhesion; cellular response to estradiol stimulus; cerebral cortex cell migration; chromatin binding; digestive tract morphogenesis; double-stranded DNA binding; embryonic placenta development; endocytic vesicle; endoplasmic reticulum membrane; endosome; endosome membrane; epidermal growth factor-activated receptor activity; extracellular space; fibroblast growth factor receptor signaling pathway; hair follicle development; innate immune response; integral to membrane; membrane raft; morphogenesis of an epithelial fold; negative regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of protein catabolic process; neurotrophin TRK receptor signaling pathway; nuclear membrane; nucleus; ossification; perinuclear region of cytoplasm; phosphatidylinositol-mediated signaling; positive regulation of DNA repair; positive regulation of DNA replication; positive regulation of ERK1 and ERK2 cascade; positive regulation of MAP kinase activity; positive regulation of catenin import into nucleus; positive regulation of cell migration; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of nitric oxide biosynthetic process; positive regulation of protein kinase B signaling cascade; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; protein heterodimerization activity; protein insertion into membrane; receptor signaling protein tyrosine kinase activity; regulation of nitric-oxide synthase activity; regulation of peptidyl-tyrosine phosphorylation; response to UV-A; salivary gland morphogenesis,PF00757;PF14843;PF07714;PF01030;,,,,,,,,,EGFR_HUMAN,Homo sapiens (Human),activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cerebral cortex cell migration [GO:0021795]; digestive tract morphogenesis [GO:0048546]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein catabolic process [GO:0042177]; ossification [GO:0001503]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to stress [GO:0006950]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337] comp63980_c0_seq1,250,46.8,0.30517206,3,5,,7.00E-09,Q38SD2,Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1),Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1),GO:0005524; GO:0005525; GO:0046872; GO:0005739; GO:0004674; GO:0007264,ATP binding; GTP binding; metal ion binding; mitochondrion; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF12796;PF16095;PF00069;PF08477;,,,,,,,,,LRRK1_HUMAN,Homo sapiens (Human),bone resorption [GO:0045453]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; small GTPase mediated signal transduction [GO:0007264] comp63987_c0_seq1,432,46.2963,1.08348093,10,11,,3.00E-11,A2AX52,Collagen alpha-4(VI) chain,Collagen alpha-4(VI) chain,GO:0007155; GO:0005581; GO:0005576; GO:0043234; GO:0070208,cell adhesion; collagen; extracellular region; protein complex; protein heterotrimerization,PF01391;PF00092;,,,,,,,,,CO6A4_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; protein heterotrimerization [GO:0070208] comp64031_c1_seq1,205,45.3659,0.67637632,3,0,,,,,,,,,6.00E-11,CHOYP_LOC100905944.1.1,,,,,,,,, comp64040_c0_seq1,615,45.3659,0.31870945,14,6,,5.00E-93,Q5BQE6,Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase),Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase),GO:0000139; GO:0007265; GO:0008762; GO:0042987; GO:0006695; GO:0005856; GO:0005829; GO:0050614; GO:0005783; GO:0005789; GO:0019899; GO:0050660; GO:0016021; GO:0030539; GO:0016020; GO:0043066; GO:0008285; GO:0043154; GO:0005634; GO:0042605; GO:0031639; GO:0008104; GO:0009725; GO:0006979; GO:0043588; GO:0009888,Golgi membrane; Ras protein signal transduction; UDP-N-acetylmuramate dehydrogenase activity; amyloid precursor protein catabolic process; cholesterol biosynthetic process; cytoskeleton; cytosol; delta24-sterol reductase activity; endoplasmic reticulum; endoplasmic reticulum membrane; enzyme binding; flavin adenine dinucleotide binding; integral to membrane; male genitalia development; membrane; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nucleus; peptide antigen binding; plasminogen activation; protein localization; response to hormone stimulus; response to oxidative stress; skin development; tissue development,PF01565;,4.00E-82,CHOYP_DHCR24.1.1,,,,,,,DHC24_RAT,Rattus norvegicus (Rat),amyloid precursor protein catabolic process [GO:0042987]; cholesterol biosynthetic process [GO:0006695]; male genitalia development [GO:0030539]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; plasminogen activation [GO:0031639]; protein localization [GO:0008104]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; response to oxidative stress [GO:0006979]; skin development [GO:0043588]; steroid metabolic process [GO:0008202]; tissue development [GO:0009888] comp64047_c0_seq1,379,43.7995,1.1163415,6,4,,4.00E-10,Q27513,Putative cytochrome P450 CYP13A4 (EC 1.14.-.-),Putative cytochrome P450 CYP13A4 (EC 1.14.-.-),GO:0020037; GO:0005506; GO:0004497; GO:0016705,"heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,C13A4_CAEEL,Caenorhabditis elegans, comp64057_c0_seq1,285,62.4561,1.1477164,2,16,,2.00E-13,P46547,Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),GO:0004177; GO:0005737; GO:0006508,aminopeptidase activity; cytoplasm; proteolysis,PF00561;,,,,,,,,,PIP_AERSO,Aeromonas sobria, comp64069_c0_seq1,383,43.342,0.64341642,3,0,,6.00E-16,Q5SSG4,GAS2-like protein 2 (Growth arrest-specific protein 2-like 2),GAS2-like protein 2 (Growth arrest-specific protein 2-like 2),GO:0051015; GO:0007050; GO:0005737; GO:0008093; GO:0005874; GO:0008017; GO:0001578; GO:0007026; GO:0001725,actin filament binding; cell cycle arrest; cytoplasm; cytoskeletal adaptor activity; microtubule; microtubule binding; microtubule bundle formation; negative regulation of microtubule depolymerization; stress fiber,PF00307;PF02187;,,,,,,,,,GA2L2_MOUSE,Mus musculus (Mouse),cell cycle arrest [GO:0007050]; microtubule bundle formation [GO:0001578]; negative regulation of microtubule depolymerization [GO:0007026] comp64075_c0_seq1,351,43.0199,0.30888282,8,10,,2.00E-07,Q63772,Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) (Growth-potentiating factor) (GPF),Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) (Growth-potentiating factor) (GPF),GO:0035754; GO:0032148; GO:0043277; GO:0060090; GO:0007596; GO:0005509; GO:0031589; GO:0035690; GO:0071333; GO:0071363; GO:0035457; GO:0009267; GO:0071307; GO:0043027; GO:0005737; GO:0007167; GO:0085029; GO:0005615; GO:0019064; GO:0008083; GO:0097241; GO:0010934; GO:0070168; GO:2000669; GO:2000352; GO:2000270; GO:0032689; GO:0050711; GO:1900165; GO:1900142; GO:0033159; GO:2000533; GO:0043433; GO:0045892; GO:0032720; GO:0010804; GO:0001764; GO:0031100; GO:0018105; GO:0001786; GO:0032008; GO:0001961; GO:0048146; GO:0010628; GO:0003104; GO:0032825; GO:0033138; GO:0050766; GO:0046827; GO:0051897; GO:0043491; GO:0072661; GO:0030296; GO:0030971; GO:0040008; GO:0042246; GO:0048771; GO:0019079; GO:0046813; GO:0005245,"B cell chemotaxis; activation of protein kinase B activity; apoptotic cell clearance; binding, bridging; blood coagulation; calcium ion binding; cell-substrate adhesion; cellular response to drug; cellular response to glucose stimulus; cellular response to growth factor stimulus; cellular response to interferon-alpha; cellular response to starvation; cellular response to vitamin K; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; enzyme linked receptor protein signaling pathway; extracellular matrix assembly; extracellular space; fusion of virus membrane with host plasma membrane; growth factor activity; hematopoietic stem cell migration to bone marrow; macrophage cytokine production; negative regulation of biomineral tissue development; negative regulation of dendritic cell apoptotic process; negative regulation of endothelial cell apoptotic process; negative regulation of fibroblast apoptotic process; negative regulation of interferon-gamma production; negative regulation of interleukin-1 secretion; negative regulation of interleukin-6 secretion; negative regulation of oligodendrocyte apoptotic process; negative regulation of protein import into nucleus, translocation; negative regulation of renal albumin absorption; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor production; negative regulation of tumor necrosis factor-mediated signaling pathway; neuron migration; organ regeneration; peptidyl-serine phosphorylation; phosphatidylserine binding; positive regulation of TOR signaling cascade; positive regulation of cytokine-mediated signaling pathway; positive regulation of fibroblast proliferation; positive regulation of gene expression; positive regulation of glomerular filtration; positive regulation of natural killer cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of phagocytosis; positive regulation of protein export from nucleus; positive regulation of protein kinase B signaling cascade; protein kinase B signaling cascade; protein targeting to plasma membrane; protein tyrosine kinase activator activity; receptor tyrosine kinase binding; regulation of growth; tissue regeneration; tissue remodeling; viral genome replication; virion attachment, binding of host cell surface receptor; voltage-gated calcium channel activity",PF07645;PF00594;PF00054;PF02210;,,,,,,,,,GAS6_RAT,Rattus norvegicus (Rat),"activation of protein kinase B activity [GO:0032148]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; blood coagulation [GO:0007596]; cell-substrate adhesion [GO:0031589]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; enzyme linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; macrophage cytokine production [GO:0010934]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; organ regeneration [GO:0031100]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein targeting to plasma membrane [GO:0072661]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]" comp64082_c0_seq1,227,44.0529,0.28752134,8,8,,5.00E-37,O75582,Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL),Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL),GO:0005524; GO:0002755; GO:0035666; GO:0007411; GO:0005737; GO:0007173; GO:0043990; GO:0043987; GO:0043988; GO:0006954; GO:0045087; GO:0070498; GO:0000287; GO:0001818; GO:0045892; GO:0048011; GO:0005654; GO:0032793; GO:0051092; GO:0035066; GO:0033129; GO:0045944; GO:0004674; GO:0051403; GO:0034166; GO:0034134; GO:0034138; GO:0034142; GO:0034146; GO:0034162; GO:0038123; GO:0038124,"ATP binding; MyD88-dependent toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; axon guidance; cytoplasm; epidermal growth factor receptor signaling pathway; histone H2A-S1 phosphorylation; histone H3-S10 phosphorylation; histone H3-S28 phosphorylation; inflammatory response; innate immune response; interleukin-1-mediated signaling pathway; magnesium ion binding; negative regulation of cytokine production; negative regulation of transcription, DNA-dependent; neurotrophin TRK receptor signaling pathway; nucleoplasm; positive regulation of CREB transcription factor activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of histone acetylation; positive regulation of histone phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; stress-activated MAPK cascade; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway",PF00069;PF00433;,2.00E-29,CHOYP_KS6A5.1.1,,,,,,,KS6A5_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; histone H2A-S1 phosphorylation [GO:0043990]; histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; histone phosphorylation [GO:0016572]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]" comp64104_c0_seq1,429,61.3054,1.11979775,0,37,,2.00E-40,Q9X909,DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme),DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0046872,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; metal ion binding,PF01131;PF01751;PF13368;,,,,,,,,,TOP1_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),DNA topological change [GO:0006265] comp64105_c0_seq1,634,40.3785,0.79261259,22,31,,1.00E-14,Q24292,Protein dachsous (Adherin),Protein dachsous (Adherin),GO:0005509; GO:0016339; GO:0050839; GO:0000904; GO:0008283; GO:0045317; GO:0045198; GO:0001737; GO:0007156; GO:0007480; GO:0005887; GO:0090176; GO:0016318; GO:0018149; GO:0004872; GO:0090175; GO:0035159; GO:0004871; GO:0035222,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; homophilic cell adhesion; imaginal disc-derived leg morphogenesis; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; ommatidial rotation; peptide cross-linking; receptor activity; regulation of establishment of planar polarity; regulation of tube length, open tracheal system; signal transducer activity; wing disc pattern formation",PF00028;,,,,,,,,,DS_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]" comp64114_c0_seq1,250,48.4,0.55501164,8,0,,7.00E-31,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-36,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp64114_c1_seq1,292,48.2877,0.59192613,11,0,,,,,,,,,2.00E-24,CHOYP_DYHC.1.3,,,,,,,,, comp64122_c0_seq1,286,52.7972,0.9517434,9,18,,1.00E-22,Q80V70,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF12662;PF07974;PF07645;PF00053;,,,,,,,,,MEGF6_MOUSE,Mus musculus (Mouse), comp64131_c0_seq1,431,47.5638,0.58435097,14,24,,1.00E-18,Q4KSH7,Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2),Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2),GO:0005524; GO:0008545; GO:0006915; GO:0072709; GO:0005829; GO:0000287; GO:0005634; GO:0018108; GO:0043525; GO:0004674; GO:0004713,ATP binding; JUN kinase kinase activity; apoptotic process; cellular response to sorbitol; cytosol; magnesium ion binding; nucleus; peptidyl-tyrosine phosphorylation; positive regulation of neuron apoptotic process; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF00069;,1.00E-23,CHOYP_MP2K7.2.2,9.00E-23,ruditapes_c24907,,,,,MP2K7_RAT,Rattus norvegicus (Rat),activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to sorbitol [GO:0072709]; JNK cascade [GO:0007254]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; response to stress [GO:0006950]; stress-activated MAPK cascade [GO:0051403] comp64152_c0_seq1,319,43.8871,0.40816728,8,9,,5.00E-06,Q9VFD5,Protein fem-1 homolog CG6966,Protein fem-1 homolog CG6966,GO:0051438; GO:0004842,regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,PF12796;PF13606;,7.00E-12,CHOYP_AGAP_AGAP004499.1.1,,,,,,,FEM1A_DROME,Drosophila melanogaster (Fruit fly),regulation of ubiquitin-protein transferase activity [GO:0051438] comp64174_c0_seq1,689,44.8476,0.34769537,18,104,,5.00E-98,Q9VQX4,Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21),Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21),GO:0009435; GO:0005829; GO:0016874; GO:0019358; GO:0004516; GO:0004514; GO:0006979,NAD biosynthetic process; cytosol; ligase activity; nicotinate nucleotide salvage; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; response to oxidative stress,PF04095;,3.00E-84,CHOYP_PNCB.1.1,,,,,,,PNCB_DROME,Drosophila melanogaster (Fruit fly),NAD biosynthetic process [GO:0009435]; nicotinate nucleotide salvage [GO:0019358]; response to oxidative stress [GO:0006979] comp64176_c0_seq1,295,45.0847,0.75588203,2,13,,5.00E-08,P97479,Unconventional myosin-VIIa,Unconventional myosin-VIIa,GO:0005524; GO:0030048; GO:0016324; GO:0060088; GO:0005516; GO:0005938; GO:0005829; GO:0050957; GO:0006886; GO:0005765; GO:0007040; GO:0042470; GO:0000146; GO:0016459; GO:0001845; GO:0032391; GO:0001917; GO:0001750; GO:0051904; GO:0048563; GO:0007605; GO:0032420; GO:0045202; GO:0007601,ATP binding; actin filament-based movement; apical plasma membrane; auditory receptor cell stereocilium organization; calmodulin binding; cell cortex; cytosol; equilibrioception; intracellular protein transport; lysosomal membrane; lysosome organization; melanosome; microfilament motor activity; myosin complex; phagolysosome assembly; photoreceptor connecting cilium; photoreceptor inner segment; photoreceptor outer segment; pigment granule transport; post-embryonic organ morphogenesis; sensory perception of sound; stereocilium; synapse; visual perception,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_MOUSE,Mus musculus (Mouse),actin filament-based movement [GO:0030048]; auditory receptor cell differentiation [GO:0042491]; auditory receptor cell stereocilium organization [GO:0060088]; cell projection organization [GO:0030030]; equilibrioception [GO:0050957]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagocytosis [GO:0006909]; phagolysosome assembly [GO:0001845]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; post-embryonic organ morphogenesis [GO:0048563]; sensory perception [GO:0007600]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp64178_c0_seq1,250,43.6,0.34034443,2,9,,1.00E-30,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,3.00E-22,CHOYP_NBEL1.1.1,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp64188_c0_seq2,217,41.0138,0.34603909,0,0,,2.00E-08,Q15438,"Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)","Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)",GO:0005086; GO:0005737; GO:0090162; GO:0005543; GO:0005886; GO:0032012; GO:0030155; GO:0005923; GO:0016192,ARF guanyl-nucleotide exchange factor activity; cytoplasm; establishment of epithelial cell polarity; phospholipid binding; plasma membrane; regulation of ARF protein signal transduction; regulation of cell adhesion; tight junction; vesicle-mediated transport,PF00169;PF01369;,2.00E-23,CHOYP_CYH1.1.1,,,,,,,CYH1_HUMAN,Homo sapiens (Human),regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192] comp64200_c0_seq1,244,38.5246,1.4745618,2,26,,1.00E-09,Q9Y2F9,BTB/POZ domain-containing protein 3,BTB/POZ domain-containing protein 3,,,PF07707;PF00651;PF08005;,,,,,,,,,BTBD3_HUMAN,Homo sapiens (Human),cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp64226_c0_seq1,360,39.4444,0.58975338,5,38,,2.00E-30,P49916,DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006284; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0043504; GO:0045910; GO:0005654; GO:0006289; GO:0007131; GO:0007283; GO:0000795; GO:0008270,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; base-excision repair; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; mitochondrial DNA repair; negative regulation of DNA recombination; nucleoplasm; nucleotide-excision repair; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex; zinc ion binding,PF04679;PF01068;PF04675;PF16759;PF00645;,7.00E-45,CHOYP_BRAFLDRAFT_119901.1.1,,,,,,,DNLI3_HUMAN,Homo sapiens (Human),"base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp64268_c0_seq2,344,43.6047,0.68060116,1,23,,9.00E-30,Q91YN5,UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)],UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)],GO:0006048; GO:0003977; GO:0005737,UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine diphosphorylase activity; cytoplasm,PF01704;,,,,,,,,,UAP1_MOUSE,Mus musculus (Mouse),UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp64284_c0_seq1,202,32.6733,0,0,9,,,,,,,,,,,6.00E-21,ruditapes_c3510,,,,,,, comp64291_c0_seq1,637,44.113,0.48866542,25,19,,7.00E-79,Q6P2B1,Transportin-3,Transportin-3,GO:0005737; GO:0005634; GO:0035048,cytoplasm; nucleus; splicing factor protein import into nucleus,PF08389;,6.00E-55,CHOYP_TNPO3.1.1,,,,,,,TNPO3_MOUSE,Mus musculus (Mouse),protein import into nucleus [GO:0006606]; splicing factor protein import into nucleus [GO:0035048] comp64329_c0_seq1,299,45.4849,0.27100574,6,33,,3.00E-10,Q5MNV6,Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7),Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7),GO:0005794; GO:0008324; GO:0016021; GO:0006829,Golgi apparatus; cation transmembrane transporter activity; integral to membrane; zinc ion transport,PF01545;,5.00E-45,CHOYP_BRAFLDRAFT_276675.1.1,,,,,,,ZNT7_CHICK,Gallus gallus (Chicken),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp64344_c0_seq1,209,54.5455,0.7118807,2,8,,,,,,,,,,,4.00E-29,ruditapes_lrc29311,,,,,,, comp64417_c0_seq2,390,46.4103,0.47741462,14,6,,3.00E-08,Q0V8T7,Contactin-associated protein like 5-3 (Cell recognition molecule Caspr5-3) (Cell recognition molecule Caspr5c) (Contactin-associated protein-like 5c),Contactin-associated protein like 5-3 (Cell recognition molecule Caspr5-3) (Cell recognition molecule Caspr5c) (Contactin-associated protein-like 5c),GO:0007155; GO:0016021,cell adhesion; integral to membrane,PF00754;PF02210;,,,,,,,,,CTP5C_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp64422_c0_seq1,366,42.0765,0.57096364,9,13,,5.00E-10,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp64428_c0_seq1,236,68.6441,1.04736729,0,4,,1.00E-11,P63540,Endonuclease III (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase),,GO:0051539; GO:0019104; GO:0006281; GO:0003906; GO:0006284; GO:0005618; GO:0003690; GO:0046872; GO:0005886,"4 iron, 4 sulfur cluster binding; DNA N-glycosylase activity; DNA repair; DNA-(apurinic or apyrimidinic site) lyase activity; base-excision repair; cell wall; double-stranded DNA binding; metal ion binding; plasma membrane",,,,,,,,,,END3_MYCTU,, comp64487_c0_seq1,371,40.4313,0.33072787,2,36,,,,,,,,,1.00E-15,CHOYP_DS.1.1,,,,,,,,, comp64529_c0_seq2,370,41.0811,0.39363683,4,8,,2.00E-51,Q8R1F6,Protein HID1 (HID1 domain-containing protein) (Protein hid-1 homolog),Protein HID1 (HID1 domain-containing protein) (Protein hid-1 homolog),GO:0005797; GO:0000138; GO:0005881; GO:0090498; GO:0006886; GO:0005886; GO:0031001,Golgi medial cisterna; Golgi trans cisterna; cytoplasmic microtubule; extrinsic to Golgi membrane; intracellular protein transport; plasma membrane; response to brefeldin A,,4.00E-73,CHOYP_BRAFLDRAFT_200209.1.1,,,,,,,HID1_MOUSE,Mus musculus (Mouse),intracellular protein transport [GO:0006886]; response to brefeldin A [GO:0031001] comp64549_c0_seq1,207,41.0628,0.57651013,3,4,,1.00E-08,Q921Y4,Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),GO:0016021; GO:0006810,integral to membrane; transport,PF05631;,,,,,,,,,MFSD5_MOUSE,Mus musculus (Mouse), comp64550_c0_seq1,363,44.3526,0.73025246,3,10,,6.00E-15,P15328,"Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18)","Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18)",GO:0031225; GO:0008219; GO:0005576; GO:0005542; GO:0046655; GO:0015884; GO:0005887; GO:0004872; GO:0006898,anchored to membrane; cell death; extracellular region; folic acid binding; folic acid metabolic process; folic acid transport; integral to plasma membrane; receptor activity; receptor-mediated endocytosis,PF03024;,,,,,,,,,FOLR1_HUMAN,Homo sapiens (Human),anterior neural tube closure [GO:0061713]; axon regeneration [GO:0031103]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; cellular response to folic acid [GO:0071231]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; folic acid metabolic process [GO:0046655]; folic acid transport [GO:0015884]; heart looping [GO:0001947]; neural crest cell migration involved in heart formation [GO:0003147]; pharyngeal arch artery morphogenesis [GO:0061626]; receptor-mediated endocytosis [GO:0006898]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] comp64577_c0_seq1,220,30.4545,0,2,8,,,,,,,,,1.00E-14,CHOYP_LOC101238346.2.2,,,,,,,,, comp64583_c0_seq2,690,44.7826,0.34781952,19,12,,5.00E-13,Q9VMA7,Transport and Golgi organization protein 1,Transport and Golgi organization protein 1,GO:0000137; GO:0000139; GO:0007030; GO:0070971; GO:0006887; GO:0016021; GO:0009306,Golgi cis cisterna; Golgi membrane; Golgi organization; endoplasmic reticulum exit site; exocytosis; integral to membrane; protein secretion,,2.00E-11,CHOYP_LOC100373461.2.2,,,,,,,TGO1_DROME,Drosophila melanogaster (Fruit fly),exocytosis [GO:0006887]; Golgi organization [GO:0007030]; positive regulation of secretion [GO:0051047]; protein secretion [GO:0009306]; secretory granule organization [GO:0033363] comp64593_c0_seq1,280,35.7143,0.34213099,1,41,,1.00E-06,Q8TF32,Zinc finger protein 431,Zinc finger protein 431,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN431_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp64618_c0_seq1,201,43.2836,0.32546455,0,17,,8.00E-17,P91443,Unconventional myosin heavy chain 6,Unconventional myosin heavy chain 6,GO:0005524; GO:0005737; GO:0003774; GO:0031476; GO:0007165,ATP binding; cytoplasm; motor activity; myosin VI complex; signal transduction,PF00373;PF00612;PF00063;PF00784;,1.00E-26,CHOYP_MYO7A.1.3,,,,,,,HUM6_CAEEL,Caenorhabditis elegans,signal transduction [GO:0007165] comp64618_c1_seq1,336,51.7857,0.58258495,0,7,,3.00E-30,Q17LW0,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp64623_c0_seq1,345,40,0.47182215,5,31,,1.00E-22,Q90660,Inhibitor of apoptosis protein (IAP) (Inhibitor of T-cell apoptosis protein),Inhibitor of apoptosis protein (IAP) (Inhibitor of T-cell apoptosis protein),GO:0006915; GO:0005737; GO:0043066; GO:0005634; GO:0008270,apoptotic process; cytoplasm; negative regulation of apoptotic process; nucleus; zinc ion binding,PF00653;PF00619;,,,,,,,,,BIR_CHICK,Gallus gallus (Chicken),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; regulation of toll-like receptor signaling pathway [GO:0034121] comp64630_c0_seq1,376,46.5426,0.78809024,2,12,,,,,,,,,2.00E-19,CHOYP_LOC100375118.2.7,,,,,,,,, comp64631_c0_seq1,307,47.2313,0.67143003,4,9,,2.00E-32,O08688,Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3),Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3),GO:0004198; GO:0009986; GO:0005622; GO:0006508,calcium-dependent cysteine-type endopeptidase activity; cell surface; intracellular; proteolysis,PF01067;PF00648;,3.00E-29,CHOYP_CAN5.1.1,,,,,,,CAN5_MOUSE,Mus musculus (Mouse),granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508] comp64651_c0_seq1,233,47.2103,0.70459645,1,20,,8.00E-06,Q9IA95,Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1),Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1),GO:0030165; GO:0016055; GO:0042813; GO:0017147; GO:0007420; GO:0030154; GO:0090103; GO:0005737; GO:0060429; GO:0005615; GO:0008406; GO:0060056; GO:0090090; GO:0061037; GO:0070367; GO:0001944,PDZ domain binding; Wnt receptor signaling pathway; Wnt-activated receptor activity; Wnt-protein binding; brain development; cell differentiation; cochlea morphogenesis; cytoplasm; epithelium development; extracellular space; gonad development; mammary gland involution; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cartilage development; negative regulation of hepatocyte differentiation; vasculature development,PF01392;PF01759;,,,,,,,,,SFRP3_CHICK,Gallus gallus (Chicken),canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of Wnt signaling pathway [GO:0030178]; non-canonical Wnt signaling pathway [GO:0035567] comp64657_c0_seq1,740,36.2162,0.84613343,52,0,,3.00E-46,Q9PWA1,Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP),Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP),GO:0005096; GO:0005737; GO:0005634; GO:0005886; GO:0038032,GTPase activator activity; cytoplasm; nucleus; plasma membrane; termination of G-protein coupled receptor signaling pathway,PF00615;,5.00E-69,CHOYP_AGAP_AGAP007127.1.1,,,,,,,RGS20_CHICK,Gallus gallus (Chicken),"cell death [GO:0008219]; cell differentiation [GO:0030154]; cellular response to organic cyclic compound [GO:0071407]; dorsal/ventral axis specification [GO:0009950]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of catenin import into nucleus [GO:0035412]; regulation of transcription, DNA-templated [GO:0006355]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp64662_c0_seq1,245,44.898,0.57001943,5,0,,5.00E-32,Q5F3L4,Protein DENND6A (DENN domain-containing protein 6A),Protein DENND6A (DENN domain-containing protein 6A),GO:0005085; GO:0055037,guanyl-nucleotide exchange factor activity; recycling endosome,PF09794;,9.00E-41,CHOYP_LOC100372051.1.1,,,,,,,F116A_CHICK,Gallus gallus (Chicken),positive regulation of GTPase activity [GO:0043547] comp64680_c0_seq1,423,37.3522,0.68036324,4,11,,7.00E-09,Q8INB9,RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB),RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB),GO:0005524; GO:0006915; GO:0009986; GO:0008362; GO:0007623; GO:0005829; GO:0031104; GO:0007427; GO:0008286; GO:0035556; GO:0019915; GO:0060292; GO:0043066; GO:0045886; GO:0035091; GO:0005886; GO:0048680; GO:0030307; GO:0045793; GO:0040018; GO:0046622; GO:0004674; GO:0008360; GO:0050773; GO:0035206; GO:0042306; GO:0006979,"ATP binding; apoptotic process; cell surface; chitin-based embryonic cuticle biosynthetic process; circadian rhythm; cytosol; dendrite regeneration; epithelial cell migration, open tracheal system; insulin receptor signaling pathway; intracellular signal transduction; lipid storage; long term synaptic depression; negative regulation of apoptotic process; negative regulation of synaptic growth at neuromuscular junction; phosphatidylinositol binding; plasma membrane; positive regulation of axon regeneration; positive regulation of cell growth; positive regulation of cell size; positive regulation of multicellular organism growth; positive regulation of organ growth; protein serine/threonine kinase activity; regulation of cell shape; regulation of dendrite development; regulation of hemocyte proliferation; regulation of protein import into nucleus; response to oxidative stress",PF00169;PF00069;PF00433;,,,,,,,,,AKT1_DROME,Drosophila melanogaster (Fruit fly),"apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]" comp6468_c0_seq1,223,43.4978,0.09605682,4,4,,3.00E-23,Q04721,Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain],Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)],GO:0000139; GO:0007220; GO:0061314; GO:0006915; GO:0060413; GO:0046849; GO:0005509; GO:0007050; GO:0001709; GO:0016049; GO:0009986; GO:0005789; GO:0005576; GO:0030097; GO:0005887; GO:0043066; GO:0008285; GO:0007399; GO:0005654; GO:0046579; GO:0003184; GO:0004872; GO:0006355; GO:0019827; GO:0006367,"Golgi membrane; Notch receptor processing; Notch signaling involved in heart development; apoptotic process; atrial septum morphogenesis; bone remodeling; calcium ion binding; cell cycle arrest; cell fate determination; cell growth; cell surface; endoplasmic reticulum membrane; extracellular region; hemopoiesis; integral to plasma membrane; negative regulation of apoptotic process; negative regulation of cell proliferation; nervous system development; nucleoplasm; positive regulation of Ras protein signal transduction; pulmonary valve morphogenesis; receptor activity; regulation of transcription, DNA-dependent; stem cell maintenance; transcription initiation from RNA polymerase II promoter",PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;,,,,,,,,,NOTC2_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; hemopoiesis [GO:0030097]; marginal zone B cell differentiation [GO:0002315]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; pulmonary valve morphogenesis [GO:0003184]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp64712_c0_seq1,421,47.981,0.75922467,5,39,,1.00E-20,Q5T1H1,Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog),Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog),GO:0005509; GO:0005576; GO:0050896; GO:0007601,calcium ion binding; extracellular region; response to stimulus; visual perception,PF00008;PF12661;PF00054;PF02210;,,,,,,,,,EYS_HUMAN,Homo sapiens (Human),detection of light stimulus involved in visual perception [GO:0050908]; skeletal muscle tissue regeneration [GO:0043403] comp64718_c1_seq1,342,48.8304,0.6038784,11,6,,4.00E-42,E9PZQ0,Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor),Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor),GO:0031674; GO:0030315; GO:0005509; GO:0005938; GO:0071313; GO:0016021; GO:0030314; GO:0006936; GO:0043931; GO:0003151; GO:0006937; GO:0014808; GO:0001666; GO:0005219; GO:0033017; GO:0048741; GO:0043588; GO:0005245,I band; T-tubule; calcium ion binding; cell cortex; cellular response to caffeine; integral to membrane; junctional membrane complex; muscle contraction; ossification involved in bone maturation; outflow tract morphogenesis; regulation of muscle contraction; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; response to hypoxia; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane; skeletal muscle fiber development; skin development; voltage-gated calcium channel activity,PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,1.00E-46,CHOYP_LOC100643070.1.1,,,,,,,RYR1_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816]; cellular response to caffeine [GO:0071313]; muscle contraction [GO:0006936]; ossification involved in bone maturation [GO:0043931]; outflow tract morphogenesis [GO:0003151]; regulation of muscle contraction [GO:0006937]; release of sequestered calcium ion into cytosol [GO:0051209]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to hypoxia [GO:0001666]; skeletal muscle fiber development [GO:0048741]; skin development [GO:0043588] comp64746_c0_seq2,335,48.9552,1.1074256,3,0,,7.00E-10,F7H9X2,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,2.00E-70,CHOYP_SMP_039300.1.1,,,,,,,TRIM2_CALJA,Callithrix jacchus (White-tufted-ear marmoset),regulation of neuron apoptotic process [GO:0043523] comp64748_c0_seq1,315,43.1746,0.56745802,5,20,,1.00E-46,Q96QK1,Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35),Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35),GO:0008219; GO:0005829; GO:0005768; GO:0005765; GO:0015031; GO:0042147,"cell death; cytosol; endosome; lysosomal membrane; protein transport; retrograde transport, endosome to Golgi",PF03635;,8.00E-37,CHOYP_VPS35.1.1,,,,,,,VPS35_HUMAN,Homo sapiens (Human),"intracellular protein transport [GO:0006886]; negative regulation of late endosome to lysosome transport [GO:1902823]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt protein secretion [GO:0061357]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; transcytosis [GO:0045056]; Wnt signaling pathway [GO:0016055]" comp64770_c0_seq1,225,42.2222,0.50089642,0,26,,1.00E-14,P40792,Ras-related protein Rac1,Ras-related protein Rac1,GO:0005525; GO:0003924; GO:0007254; GO:0051017; GO:0034334; GO:0048675; GO:0007413; GO:0007298; GO:0035212; GO:0030866; GO:0005829; GO:0048813; GO:0071907; GO:0046843; GO:0046664; GO:0007394; GO:0048615; GO:0042067; GO:0019897; GO:0007390; GO:0008347; GO:0008258; GO:0007516; GO:0035099; GO:0035320; GO:0002433; GO:0030032; GO:0035011; GO:0008078; GO:0007017; GO:0016335; GO:0008045; GO:0048747; GO:0007520; GO:0051450; GO:0010593; GO:0007422; GO:0051491; GO:0071902; GO:0050770; GO:0051726; GO:0048814; GO:0045610; GO:0051963; GO:0006974; GO:0016028; GO:0042052; GO:0007435; GO:0050975; GO:0007264; GO:0007426; GO:0007419,"GTP binding; GTPase activity; JNK cascade; actin filament bundle assembly; adherens junction maintenance; axon extension; axonal fasciculation; border follicle cell migration; cell competition in a multicellular organism; cortical actin cytoskeleton organization; cytosol; dendrite morphogenesis; determination of digestive tract left/right asymmetry; dorsal appendage formation; dorsal closure, amnioserosa morphology change; dorsal closure, elongation of leading edge cells; embryonic anterior midgut (ectodermal) morphogenesis; establishment of ommatidial planar polarity; extrinsic to plasma membrane; germ-band shortening; glial cell migration; head involution; hemocyte development; hemocyte migration; imaginal disc-derived wing hair site selection; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; lamellipodium assembly; melanotic encapsulation of foreign target; mesodermal cell migration; microtubule-based process; morphogenesis of larval imaginal disc epithelium; motor neuron axon guidance; muscle fiber development; myoblast fusion; myoblast proliferation; negative regulation of lamellipodium assembly; peripheral nervous system development; positive regulation of filopodium assembly; positive regulation of protein serine/threonine kinase activity; regulation of axonogenesis; regulation of cell cycle; regulation of dendrite morphogenesis; regulation of hemocyte differentiation; regulation of synapse assembly; response to DNA damage stimulus; rhabdomere; rhabdomere development; salivary gland morphogenesis; sensory perception of touch; small GTPase mediated signal transduction; tracheal outgrowth, open tracheal system; ventral cord development",PF00071;,,,,,,,,,RAC1_DROME,Drosophila melanogaster (Fruit fly),"actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; adherens junction maintenance [GO:0034334]; axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; border follicle cell migration [GO:0007298]; cell-cell junction organization [GO:0045216]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cortical actin cytoskeleton organization [GO:0030866]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; establishment of ommatidial planar polarity [GO:0042067]; establishment of tissue polarity [GO:0007164]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; mesodermal cell migration [GO:0008078]; microtubule-based process [GO:0007017]; morphogenesis of larval imaginal disc epithelium [GO:0016335]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle fiber development [GO:0048747]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of axonogenesis [GO:0050770]; regulation of cell cycle [GO:0051726]; regulation of dendrite morphogenesis [GO:0048814]; regulation of hemocyte differentiation [GO:0045610]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; ventral cord development [GO:0007419]" comp64779_c0_seq1,755,43.4437,0.51438382,27,44,,7.00E-115,Q810B6,Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif),Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif),GO:0006897; GO:0010008; GO:0046872,endocytosis; endosome membrane; metal ion binding,PF00023;PF12796;PF00651;PF01363;,1.00E-96,CHOYP_LOC100372945.2.2,,,,,,,ANFY1_MOUSE,Mus musculus (Mouse),"endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" comp64784_c0_seq1,446,49.7758,0.94519018,7,42,,5.00E-68,Q498S8,Frizzled-8 (Fz-8),Frizzled-8 (Fz-8),GO:0004930; GO:0005794; GO:0030165; GO:0033077; GO:0042813; GO:0017147; GO:0007409; GO:0007420; GO:0060070; GO:0042995; GO:0005737; GO:0009790; GO:0008406; GO:0016021; GO:0005886; GO:0001944,G-protein coupled receptor activity; Golgi apparatus; PDZ domain binding; T cell differentiation in thymus; Wnt-activated receptor activity; Wnt-protein binding; axonogenesis; brain development; canonical Wnt receptor signaling pathway; cell projection; cytoplasm; embryo development; gonad development; integral to membrane; plasma membrane; vasculature development,PF01534;PF01392;,4.00E-42,CHOYP_LOC100313610.1.2,,,,,,,FZD8_RAT,Rattus norvegicus (Rat),canonical Wnt signaling pathway [GO:0060070]; multicellular organism development [GO:0007275]; non-canonical Wnt signaling pathway [GO:0035567] comp64801_c0_seq2,654,43.578,0.93876863,16,13,,9.00E-31,Q3UHR0,BAH and coiled-coil domain-containing protein 1,BAH and coiled-coil domain-containing protein 1,GO:0003677,DNA binding,PF01426;,,,,,,,,,BAHC1_MOUSE,Mus musculus (Mouse),chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507] comp64802_c0_seq1,292,43.8356,0.58381756,0,28,,6.00E-08,P33450,Cadherin-related tumor suppressor (Protein fat),Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito],GO:0005509; GO:0016339; GO:0050839; GO:0030054; GO:0000904; GO:0008283; GO:0045317; GO:0048105; GO:0045198; GO:0001737; GO:0035329; GO:0007156; GO:0007446; GO:0005887; GO:0090176; GO:0030178; GO:0008285; GO:0045571; GO:0016318; GO:0018149; GO:0004872; GO:0035159,"calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; cell junction; cell morphogenesis involved in differentiation; cell proliferation; equator specification; establishment of body hair planar orientation; establishment of epithelial cell apical/basal polarity; establishment of imaginal disc-derived wing hair orientation; hippo signaling cascade; homophilic cell adhesion; imaginal disc growth; integral to plasma membrane; microtubule cytoskeleton organization involved in establishment of planar polarity; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of imaginal disc growth; ommatidial rotation; peptide cross-linking; receptor activity; regulation of tube length, open tracheal system",PF00028;PF00008;PF00054;PF02210;,,,,,,,,,FAT_DROME,Drosophila melanogaster (Fruit fly),"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]" comp64812_c0_seq1,300,41,0.39794202,12,6,,1.00E-23,Q92820,Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase),Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase),GO:0005829; GO:0005615; GO:0034722; GO:0006541; GO:0005764; GO:0042470; GO:0042493; GO:0045471; GO:0032868; GO:0010043,cytosol; extracellular space; gamma-glutamyl-peptidase activity; glutamine metabolic process; lysosome; melanosome; response to drug; response to ethanol; response to insulin stimulus; response to zinc ion,PF07722;,,,,,,,,,GGH_HUMAN,Homo sapiens (Human),glutamine metabolic process [GO:0006541]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900] comp64814_c0_seq1,286,47.9021,0.49060429,3,19,,2.00E-44,A7SMW7,"L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)","L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)",GO:0047545; GO:0005739,2-hydroxyglutarate dehydrogenase activity; mitochondrion,PF01266;,1.00E-33,CHOYP_PHUM_PHUM349810.1.2,,,,,,,L2HDH_NEMVE,Nematostella vectensis (Starlet sea anemone), comp64839_c0_seq1,208,43.2692,1.26926011,4,5,,9.00E-15,O00548,Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) (H-Delta-1),Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) (H-Delta-1),GO:0007220; GO:0007219; GO:0005509; GO:0001709; GO:0007267; GO:0007386; GO:0031410; GO:0005576; GO:0001947; GO:0030097; GO:0048839; GO:0005887; GO:0070986; GO:0072070; GO:0045608; GO:0045638; GO:0097150; GO:0045747; GO:0045944; GO:0072014; GO:0030155; GO:0001757,Notch receptor processing; Notch signaling pathway; calcium ion binding; cell fate determination; cell-cell signaling; compartment pattern specification; cytoplasmic vesicle; extracellular region; heart looping; hemopoiesis; inner ear development; integral to plasma membrane; left/right axis specification; loop of Henle development; negative regulation of auditory receptor cell differentiation; negative regulation of myeloid cell differentiation; neuronal stem cell maintenance; positive regulation of Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; proximal tubule development; regulation of cell adhesion; somite specification,PF01414;PF00008;PF07657;,,,,,,,,,DLL1_HUMAN,Homo sapiens (Human),astrocyte development [GO:0014002]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-mediated endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; negative regulation of auditory receptor cell differentiation [GO:0045608]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; nephron development [GO:0072006]; neuronal stem cell population maintenance [GO:0097150]; neuron fate specification [GO:0048665]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proximal/distal pattern formation [GO:0009954]; proximal tubule development [GO:0072014]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of energy homeostasis [GO:2000505]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] comp64857_c0_seq1,344,41.8605,0.62249925,1,19,,9.00E-37,P11416,Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1),Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1),GO:0060010; GO:0043277; GO:0071391; GO:0071222; GO:0071300; GO:0060591; GO:0031490; GO:0005737; GO:0030425; GO:0007281; GO:0003417; GO:0030520; GO:0035264; GO:0061037; GO:0045596; GO:0030853; GO:0032689; GO:0000122; GO:0045892; GO:0045947; GO:0032720; GO:0043025; GO:0000790; GO:0005634; GO:0045630; GO:0051099; GO:0045787; GO:0008284; GO:0010628; GO:0032736; GO:0032753; GO:0032754; GO:0045944; GO:0006468; GO:0030852; GO:0032355; GO:0032526; GO:0001972; GO:0003708; GO:0044323; GO:0043565; GO:0007283; GO:0003707; GO:0003713; GO:0003714; GO:0044212; GO:0001657; GO:0055012; GO:0008270,"Sertoli cell fate commitment; apoptotic cell clearance; cellular response to estrogen stimulus; cellular response to lipopolysaccharide; cellular response to retinoic acid; chondroblast differentiation; chromatin DNA binding; cytoplasm; dendrite; germ cell development; growth plate cartilage development; intracellular estrogen receptor signaling pathway; multicellular organism growth; negative regulation of cartilage development; negative regulation of cell differentiation; negative regulation of granulocyte differentiation; negative regulation of interferon-gamma production; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of translational initiation; negative regulation of tumor necrosis factor production; neuronal cell body; nuclear chromatin; nucleus; positive regulation of T-helper 2 cell differentiation; positive regulation of binding; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of gene expression; positive regulation of interleukin-13 production; positive regulation of interleukin-4 production; positive regulation of interleukin-5 production; positive regulation of transcription from RNA polymerase II promoter; protein phosphorylation; regulation of granulocyte differentiation; response to estradiol stimulus; response to retinoic acid; retinoic acid binding; retinoic acid receptor activity; retinoic acid-responsive element binding; sequence-specific DNA binding; spermatogenesis; steroid hormone receptor activity; transcription coactivator activity; transcription corepressor activity; transcription regulatory region DNA binding; ureteric bud development; ventricular cardiac muscle cell differentiation; zinc ion binding",PF00104;PF00105;,2.00E-20,CHOYP_RARB.1.3,,,,,,,RARA_MOUSE,Mus musculus (Mouse),"apoptotic cell clearance [GO:0043277]; bone development [GO:0060348]; cellular response to estrogen stimulus [GO:0071391]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; chondroblast differentiation [GO:0060591]; embryonic camera-type eye development [GO:0031076]; face development [GO:0060324]; female pregnancy [GO:0007565]; germ cell development [GO:0007281]; glandular epithelial cell development [GO:0002068]; growth plate cartilage development [GO:0003417]; hippocampus development [GO:0021766]; limb development [GO:0060173]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; negative regulation of tumor necrosis factor production [GO:0032720]; neural tube closure [GO:0001843]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of binding [GO:0051099]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland development [GO:0030850]; protein phosphorylation [GO:0006468]; regulation of granulocyte differentiation [GO:0030852]; regulation of myelination [GO:0031641]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]; retinoic acid receptor signaling pathway [GO:0048384]; Sertoli cell fate commitment [GO:0060010]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; trachea cartilage development [GO:0060534]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ventricular cardiac muscle cell differentiation [GO:0055012]" comp64890_c0_seq1,482,41.2863,0.64006392,0,74,,2.00E-15,Q6CGG3,FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase),GO:0005783; GO:0003755; GO:0006457; GO:0000413,endoplasmic reticulum; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF00254;,,,,,,,,,FKBP2_YARLI,Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica),chaperone-mediated protein folding [GO:0061077] comp64895_c0_seq1,781,44.0461,0.67083114,31,53,,4.00E-41,Q9NW15,Anoctamin-10 (Transmembrane protein 16K),Anoctamin-10 (Transmembrane protein 16K),GO:0008219; GO:0016021; GO:0005622; GO:0034220; GO:0005886,cell death; integral to membrane; intracellular; ion transmembrane transport; plasma membrane,PF04547;,2.00E-18,CHOYP_BRAFLDRAFT_75374.1.1,,,,,,,ANO10_HUMAN,Homo sapiens (Human),cation transport [GO:0006812]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220] comp64902_c0_seq1,450,35.1111,1.14332152,8,14,,3.00E-06,Q9NBX4,Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,1.00E-14,ruditapes_c12969,,,,,RTXE_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp64907_c0_seq1,250,40,0.60240964,2,23,,2.00E-07,Q6E2N3,E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33),GO:0003677; GO:0016874; GO:0005634; GO:0016567; GO:0006355; GO:0006351; GO:0008270,"DNA binding; ligase activity; nucleus; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00439;PF00628;PF00643;,,,,,,,,,TRI33_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]" comp64968_c0_seq1,342,38.3041,0.77485602,5,29,,1.00E-13,Q16YG0,Cdc42 homolog,Cdc42 homolog,GO:0005525; GO:0005912; GO:0005622; GO:0045185; GO:0007275; GO:0005886; GO:0045860; GO:0007264,GTP binding; adherens junction; intracellular; maintenance of protein location; multicellular organismal development; plasma membrane; positive regulation of protein kinase activity; small GTPase mediated signal transduction,PF00071;,7.00E-13,CHOYP_CDC42.4.11,,,,,,,CDC42_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),maintenance of protein location [GO:0045185]; multicellular organism development [GO:0007275]; positive regulation of protein kinase activity [GO:0045860]; small GTPase mediated signal transduction [GO:0007264] comp64974_c0_seq1,593,44.688,0.44060379,14,53,,2.00E-12,O15146,"Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)","Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)",GO:0005524; GO:0030154; GO:0030054; GO:0030198; GO:0005887; GO:0007613; GO:0007275; GO:0031594; GO:0010628; GO:0043525; GO:2000541; GO:0001934; GO:0045211; GO:0046777; GO:0004713; GO:0008582; GO:0006355; GO:0071340; GO:0004714; GO:0007169,"ATP binding; cell differentiation; cell junction; extracellular matrix organization; integral to plasma membrane; memory; multicellular organismal development; neuromuscular junction; positive regulation of gene expression; positive regulation of neuron apoptotic process; positive regulation of protein geranylgeranylation; positive regulation of protein phosphorylation; postsynaptic membrane; protein autophosphorylation; protein tyrosine kinase activity; regulation of synaptic growth at neuromuscular junction; regulation of transcription, DNA-dependent; skeletal muscle acetylcholine-gated channel clustering; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway",PF01392;PF07679;PF07714;,,,,,,,,,MUSK_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; memory [GO:0007613]; multicellular organism development [GO:0007275]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp64978_c0_seq1,223,68.1614,1.0927049,0,8,,1.00E-12,P67666,Uncharacterized HTH-type transcriptional regulator Mb2007c,Uncharacterized HTH-type transcriptional regulator Mb2007c,GO:0003677; GO:0003700; GO:0006351,"DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00126;PF03466;,,,,,,,,,Y2007_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),"transcription, DNA-templated [GO:0006351]" comp64992_c0_seq1,662,45.6193,0.50407092,14,44,,9.00E-22,Q8N9B5,Junction-mediating and -regulatory protein,Junction-mediating and -regulatory protein,GO:0070060; GO:0034314; GO:0006281; GO:0070358; GO:0007050; GO:0031252; GO:0005737; GO:0005856; GO:0005634; GO:0043065; GO:0051091; GO:0006357; GO:0003713,'de novo' actin filament nucleation; Arp2/3 complex-mediated actin nucleation; DNA repair; actin polymerization-dependent cell motility; cell cycle arrest; cell leading edge; cytoplasm; cytoskeleton; nucleus; positive regulation of apoptotic process; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of transcription from RNA polymerase II promoter; transcription coactivator activity,PF15871;PF15920;,,,,,,,,,JMY_HUMAN,Homo sapiens (Human),'de novo' actin filament nucleation [GO:0070060]; actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; cell cycle arrest [GO:0007050]; DNA repair [GO:0006281]; positive regulation of apoptotic process [GO:0043065]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp64992_c1_seq1,594,39.0572,0.52126621,16,41,,7.00E-18,A8E4X8,Junction-mediating and -regulatory protein,Junction-mediating and -regulatory protein,GO:0070060; GO:0034314; GO:0006281; GO:0070358; GO:0031252; GO:0005737; GO:0005856; GO:0005634,'de novo' actin filament nucleation; Arp2/3 complex-mediated actin nucleation; DNA repair; actin polymerization-dependent cell motility; cell leading edge; cytoplasm; cytoskeleton; nucleus,PF15871;PF15920;,,,,,,,,,JMY_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),'de novo' actin filament nucleation [GO:0070060]; actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; DNA repair [GO:0006281]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp65020_c0_seq1,944,41.6314,0.50599757,22,90,,3.00E-21,Q3USL1,Kelch domain-containing protein 9,Kelch domain-containing protein 9,,,,,,,,,,,,KLDC9_MOUSE,Mus musculus (Mouse), comp65023_c0_seq1,245,35.102,0.54275587,2,20,,,,,,,,,1.00E-20,CHOYP_BRAFLDRAFT_106560.2.14,,,,,,,,, comp65050_c0_seq1,228,46.4912,0.58080827,2,10,,1.00E-17,Q8TD20,"Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)","Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)",GO:0012505; GO:0015758; GO:0016021; GO:0048471; GO:0005886; GO:0022891; GO:0055085,endomembrane system; glucose transport; integral to membrane; perinuclear region of cytoplasm; plasma membrane; substrate-specific transmembrane transporter activity; transmembrane transport,PF00083;,2.00E-24,CHOYP_GTR12.1.1,,,,,,,GTR12_HUMAN,Homo sapiens (Human),glucose import [GO:0046323] comp65069_c0_seq1,251,33.8645,0.45818909,5,0,,8.00E-10,Q9P2E3,NFX1-type zinc finger-containing protein 1,NFX1-type zinc finger-containing protein 1,GO:0046872,metal ion binding,,,,,,,,,,ZNFX1_HUMAN,Homo sapiens (Human), comp65076_c0_seq1,221,49.7738,1.17462722,0,10,,9.00E-21,Q5FVR2,Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase),Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase),GO:0004645; GO:0006206; GO:0006213; GO:0016154; GO:0009032,phosphorylase activity; pyrimidine nucleobase metabolic process; pyrimidine nucleoside metabolic process; pyrimidine-nucleoside phosphorylase activity; thymidine phosphorylase activity,PF02885;PF00591;PF07831;,,,,,,,,,TYPH_RAT,Rattus norvegicus (Rat),pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleotide metabolic process [GO:0006220] comp65095_c0_seq1,267,40.0749,0.49084938,4,20,,,,,,,,,,,3.00E-13,ruditapes_c9537,,,,,,, comp65139_c1_seq1,441,41.4966,0.7924975,6,29,,4.00E-14,Q24307,Apoptosis 2 inhibitor (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2) (dIAP2),Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2),GO:0050829; GO:0043066; GO:0043154; GO:0061057; GO:0006964; GO:0033160; GO:0070534; GO:0007423; GO:0008270,"defense response to Gram-negative bacterium; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidoglycan recognition protein signaling pathway; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; positive regulation of protein import into nucleus, translocation; protein K63-linked ubiquitination; sensory organ development; zinc ion binding",PF00653;,,,,,,,,,IAP2_DROME,Drosophila melanogaster (Fruit fly),"defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]" comp65142_c0_seq1,337,45.9941,0.45339098,21,17,,6.00E-15,Q802D3,Exportin-4,Exportin-4,GO:0005737; GO:0005634; GO:0015031,cytoplasm; nucleus; protein transport,PF08767;,6.00E-13,CHOYP_XPO4.1.1,,,,,,,XPO4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein export from nucleus [GO:0006611] comp65162_c0_seq1,230,46.9565,0.7139558,2,0,,9.00E-18,Q9Z258,Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,,,,,,,,,KCNT1_RAT,Rattus norvegicus (Rat),potassium ion transport [GO:0006813] comp65162_c0_seq2,241,47.3029,0.59754115,3,0,,5.00E-16,Q6UVM4,Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1),Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1),GO:0005524; GO:0015269; GO:0005228; GO:0005249; GO:0008076,ATP binding; calcium-activated potassium channel activity; intracellular sodium activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,,,,,,,,,KCNT2_RAT,Rattus norvegicus (Rat), comp65254_c0_seq1,231,41.5584,1.06277759,0,28,,,,,,,,,,,5.00E-23,ruditapes2_c2362,,,,,,, comp65285_c0_seq1,401,44.8878,0.49636066,12,7,,7.00E-13,Q80TY5,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp65292_c0_seq1,330,34.5455,0.61202411,4,32,,3.00E-09,P21520,Protein scabrous,Protein scabrous,GO:0007219; GO:0007460; GO:0005576; GO:0016321; GO:0008587; GO:0005770; GO:0046331; GO:0016318; GO:0045468; GO:0097305; GO:0004871,Notch signaling pathway; R8 cell fate commitment; extracellular region; female meiosis chromosome segregation; imaginal disc-derived wing margin morphogenesis; late endosome; lateral inhibition; ommatidial rotation; regulation of R8 cell spacing in compound eye; response to alcohol; signal transducer activity,PF00147;,,,,,,,,,SCA_DROME,Drosophila melanogaster (Fruit fly),chaeta morphogenesis [GO:0008407]; compound eye development [GO:0048749]; female meiosis chromosome segregation [GO:0016321]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; ommatidial rotation [GO:0016318]; R8 cell fate commitment [GO:0007460]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to alcohol [GO:0097305] comp65294_c0_seq1,231,31.1688,0.35913986,28,40,,1.00E-23,Q9BSK1,Zinc finger protein 577,Zinc finger protein 577,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,1.00E-14,CHOYP_PRDM9.1.1,,,,,,,ZN577_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp65298_c0_seq1,245,39.1837,0.32087491,7,0,,3.00E-08,Q0P4X6,Zinc finger and BTB domain-containing protein 44,Zinc finger and BTB domain-containing protein 44,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT44_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp65319_c0_seq1,253,42.2925,0.63365209,10,1,,5.00E-18,Q08882,Probable nuclear hormone receptor HR3 (mHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (mHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0005634; GO:0043565; GO:0003707; GO:0004887; GO:0008270,nucleus; sequence-specific DNA binding; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,,,,,,,,,HR3_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm),"transcription, DNA-templated [GO:0006351]" comp65320_c0_seq1,270,37.7778,0.64092326,10,16,,5.00E-09,Q9CEF5,Probable serine/threonine-protein kinase PknB (EC 2.7.11.1),Probable serine/threonine-protein kinase PknB (EC 2.7.11.1),GO:0005524; GO:0008658; GO:0004674,ATP binding; penicillin binding; protein serine/threonine kinase activity,PF03793;PF00069;,4.00E-14,CHOYP_LOC100169297.1.1,,,,,,,PKNB_LACLA,Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis), comp65363_c1_seq1,295,44.0678,0.6458256,0,6,,2.00E-24,Q9ES38,Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR),Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR),GO:0005524; GO:0009925; GO:0006699; GO:0008206; GO:0047747; GO:0015245; GO:0030176; GO:0043231; GO:0046951; GO:0015911; GO:0043234; GO:0032403; GO:0006642; GO:0000038; GO:0031957,ATP binding; basal plasma membrane; bile acid biosynthetic process; bile acid metabolic process; cholate-CoA ligase activity; fatty acid transporter activity; integral to endoplasmic reticulum membrane; intracellular membrane-bounded organelle; ketone body biosynthetic process; plasma membrane long-chain fatty acid transport; protein complex; protein complex binding; triglyceride mobilization; very long-chain fatty acid metabolic process; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,S27A5_RAT,Rattus norvegicus (Rat),bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; ketone body biosynthetic process [GO:0046951]; plasma membrane long-chain fatty acid transport [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038] comp65374_c1_seq1,354,38.4181,0.7814282,10,10,,8.00E-20,Q96LK0,Centrosomal protein of 19 kDa (Cep19),Centrosomal protein of 19 kDa (Cep19),GO:0005814; GO:0000922,centriole; spindle pole,PF14933;,,,,,,,,,CEP19_HUMAN,Homo sapiens (Human), comp65379_c0_seq1,244,40.9836,0.30384967,5,16,,1.00E-08,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,7.00E-17,CHOYP_BRAFLDRAFT_93030.1.1,,,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp65388_c0_seq1,282,44.6809,0.93282106,10,0,,8.00E-15,O14975,"Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)","Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)",GO:0005524; GO:0006699; GO:0005788; GO:0001561; GO:0006635; GO:0015245; GO:0030176; GO:0005779; GO:0044539; GO:0004467; GO:0097089; GO:0005739; GO:0050197; GO:0070251; GO:0042760; GO:0031957,ATP binding; bile acid biosynthetic process; endoplasmic reticulum lumen; fatty acid alpha-oxidation; fatty acid beta-oxidation; fatty acid transporter activity; integral to endoplasmic reticulum membrane; integral to peroxisomal membrane; long-chain fatty acid import; long-chain fatty acid-CoA ligase activity; methyl-branched fatty acid metabolic process; mitochondrion; phytanate-CoA ligase activity; pristanate-CoA ligase activity; very long-chain fatty acid catabolic process; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,S27A2_HUMAN,Homo sapiens (Human),bile acid biosynthetic process [GO:0006699]; fatty acid alpha-oxidation [GO:0001561]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; methyl-branched fatty acid metabolic process [GO:0097089]; very long-chain fatty acid catabolic process [GO:0042760] comp65398_c0_seq1,274,35.7664,0.92593826,6,42,,9.00E-30,Q13360,Zinc finger protein 177,Zinc finger protein 177,GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN177_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp65414_c0_seq1,291,41.5808,0.41667159,7,0,,3.00E-09,Q6NRS1,Inhibitor of Bruton tyrosine kinase (IBtk),Inhibitor of Bruton tyrosine kinase (IBtk),GO:0005737; GO:0016020,cytoplasm; membrane,PF12796;PF00651;PF00415;,,,,,,,,,IBTK_XENLA,Xenopus laevis (African clawed frog), comp65427_c0_seq1,280,61.4286,1.22391652,0,11,,3.00E-12,C5C3F6,50S ribosomal protein L28,50S ribosomal protein L28,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF00830;,,,,,,,,,RL28_BEUC1,Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432),translation [GO:0006412] comp65430_c0_seq1,344,42.7326,0.46264759,15,18,,1.00E-47,A0MGZ7,Heparan-sulfate 6-O-sulfotransferase 3 (HS 6-OST-3) (EC 2.8.2.-),Heparan-sulfate 6-O-sulfotransferase 3 (HS 6-OST-3) (EC 2.8.2.-),GO:0016021; GO:0008146,integral to membrane; sulfotransferase activity,PF03567;,,,,,,,,,H6ST3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" comp65458_c0_seq1,235,46.8085,0.78121242,2,22,,4.00E-06,Q8JIV8,Snaclec clone 2100755 (C-type lectin clone 2100755),Snaclec clone 2100755 (C-type lectin clone 2100755),GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,SVLEC_DEIAC,Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus), comp65494_c0_seq2,338,55.9172,1.4458039,0,16,,4.00E-06,Q6XPR3,Repetin,Repetin,GO:0005509; GO:0005578,calcium ion binding; proteinaceous extracellular matrix,PF01023;,,,,,,,,,RPTN_HUMAN,Homo sapiens (Human), comp65508_c0_seq1,286,43.7063,1.17624389,3,11,,4.00E-13,P50234,3-alpha-hydroxysteroid sulfotransferase (EC 2.8.2.2) (Alcohol sulfotransferase) (HST1),3-alpha-hydroxysteroid sulfotransferase (EC 2.8.2.2) (Alcohol sulfotransferase) (HST1),GO:0004027; GO:0005737; GO:0008202,alcohol sulfotransferase activity; cytoplasm; steroid metabolic process,PF00685;,,,,,,,,,SUHA_CAVPO,Cavia porcellus (Guinea pig),steroid metabolic process [GO:0008202] comp65529_c0_seq1,268,40.6716,0.55388554,5,6,,6.00E-08,O94761,"ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)","ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)",GO:0005524; GO:0043140; GO:0006310; GO:0006281; GO:0006260; GO:0000733; GO:0000405; GO:0005737; GO:0007275; GO:0005634; GO:0008270,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA recombination; DNA repair; DNA replication; DNA strand renaturation; bubble DNA binding; cytoplasm; multicellular organismal development; nucleus; zinc ion binding,PF00270;PF11719;PF00271;,,,,,,,,,RECQ4_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; multicellular organism development [GO:0007275] comp65530_c0_seq1,243,42.7984,0.77832259,9,4,,1.00E-06,O08653,Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog),Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005634; GO:0030529,"ATP binding; RNA binding; chromosome, telomeric region; nucleus; ribonucleoprotein complex",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_RAT,Rattus norvegicus (Rat),RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722] comp65540_c0_seq1,254,39.3701,0.51082523,10,0,,9.00E-26,A1A4L0,Sorting nexin-4,Sorting nexin-4,GO:0007154; GO:0005868; GO:0031901; GO:0032456; GO:0035091; GO:0015031,cell communication; cytoplasmic dynein complex; early endosome membrane; endocytic recycling; phosphatidylinositol binding; protein transport,PF00787;,1.00E-51,CHOYP_BRAFLDRAFT_120826.1.1,,,,,,,SNX4_BOVIN,Bos taurus (Bovine),endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; vesicle organization [GO:0016050] comp65540_c1_seq1,276,39.8551,0.2884453,6,6,,3.00E-25,Q91YJ2,Sorting nexin-4,Sorting nexin-4,GO:0007154; GO:0005868; GO:0031901; GO:0032456; GO:0035091; GO:0015031,cell communication; cytoplasmic dynein complex; early endosome membrane; endocytic recycling; phosphatidylinositol binding; protein transport,PF00787;,,,,,,,,,SNX4_MOUSE,Mus musculus (Mouse),endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; vesicle organization [GO:0016050] comp65561_c0_seq1,342,37.1345,0.25789694,6,25,,3.00E-16,Q00657,Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen),Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen),GO:0001525; GO:0016324; GO:0006954; GO:0005887; GO:0031258; GO:0010977; GO:0048663; GO:0016322; GO:0010226; GO:0004871; GO:0048771,angiogenesis; apical plasma membrane; inflammatory response; integral to plasma membrane; lamellipodium membrane; negative regulation of neuron projection development; neuron fate commitment; neuron remodeling; response to lithium ion; signal transducer activity; tissue remodeling,PF00054;PF02210;,,,,,,,,,CSPG4_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; cell migration [GO:0016477]; inflammatory response [GO:0006954]; negative regulation of neuron projection development [GO:0010977]; neuron remodeling [GO:0016322]; response to lithium ion [GO:0010226]; tissue remodeling [GO:0048771] comp65609_c0_seq1,1054,47.0588,0.5339771,51,41,,1.00E-141,Q9VQX4,Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21),Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21),GO:0009435; GO:0005829; GO:0016874; GO:0019358; GO:0004516; GO:0004514; GO:0006979,NAD biosynthetic process; cytosol; ligase activity; nicotinate nucleotide salvage; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; response to oxidative stress,PF04095;,2.00E-121,CHOYP_PNCB.1.1,,,,,,,PNCB_DROME,Drosophila melanogaster (Fruit fly),NAD biosynthetic process [GO:0009435]; nicotinate nucleotide salvage [GO:0019358]; response to oxidative stress [GO:0006979] comp65628_c0_seq1,237,48.5232,0.36458982,2,0,,2.00E-16,Q9JHB4,WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD),WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD),,,PF00400;,,,,,,,,,WDR31_MOUSE,Mus musculus (Mouse), comp65631_c0_seq2,565,44.0708,0.8398736,5,24,,2.00E-28,Q92766,Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1),Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1),GO:0003677; GO:0007265; GO:0005737; GO:0046872; GO:0007275; GO:0045892; GO:0016604; GO:0016607; GO:0045893; GO:0003700; GO:0006366,"DNA binding; Ras protein signal transduction; cytoplasm; metal ion binding; multicellular organismal development; negative regulation of transcription, DNA-dependent; nuclear body; nuclear speck; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter",PF13912;,1.00E-37,CHOYP_ZN836.1.1,,,,,,,RREB1_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; Ras protein signal transduction [GO:0007265]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp6563_c0_seq1,254,59.0551,1.19225009,0,4,,9.00E-06,P63629,Homoserine dehydrogenase (HDH) (EC 1.1.1.3),,GO:0050661; GO:0016597; GO:0005618; GO:0040007; GO:0004412; GO:0009097; GO:0009086; GO:0005886; GO:0009088,NADP binding; amino acid binding; cell wall; growth; homoserine dehydrogenase activity; isoleucine biosynthetic process; methionine biosynthetic process; plasma membrane; threonine biosynthetic process,,,,,,,,,,DHOM_MYCTU,, comp65673_c0_seq2,883,38.3918,0.37920975,12,31,,2.00E-40,Q8N3C0,"Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)","Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)",GO:0005524; GO:0043140; GO:0006307; GO:0008283; GO:0005737; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA dealkylation involved in DNA repair; cell proliferation; cytoplasm; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00270;PF00271;PF02889;,5.00E-38,CHOYP_ASCC3.1.1,,,,,,,ASCC3_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp65681_c0_seq1,236,36.8644,0.38726186,5,7,,1.00E-13,Q5UR67,Uncharacterized protein R617,N-glycosidase R617 (EC 3.2.2.-) (Riboflavin biosynthesis intermediates N-glycosidase),,,PF08719;,,,,,,,,,YR617_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),metabolic process [GO:0008152] comp65702_c0_seq1,208,67.3077,1.10991128,0,13,,2.00E-26,Q8XWD0,Tyrosine recombinase XerD,Tyrosine recombinase XerD,GO:0003677; GO:0007049; GO:0051301; GO:0007059; GO:0005737; GO:0006313; GO:0009037,"DNA binding; cell cycle; cell division; chromosome segregation; cytoplasm; transposition, DNA-mediated; tyrosine-based site-specific recombinase activity",PF02899;PF00589;,,,,,,,,,XERD_RALSO,Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum),"cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; transposition, DNA-mediated [GO:0006313]" comp65717_c0_seq1,570,48.2456,0.85653323,1,71,,1.00E-28,Q96KG7,Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10),Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10),GO:0016323; GO:0042995; GO:0034109; GO:0016021; GO:0055001; GO:0001891; GO:0043654; GO:0051147; GO:0048641; GO:0014719; GO:0014816; GO:0014841,basolateral plasma membrane; cell projection; homotypic cell-cell adhesion; integral to membrane; muscle cell development; phagocytic cup; recognition of apoptotic cell; regulation of muscle cell differentiation; regulation of skeletal muscle tissue development; satellite cell activation; satellite cell differentiation; satellite cell proliferation,PF12661;PF00053;,,,,,,,,,MEG10_HUMAN,Homo sapiens (Human),homotypic cell-cell adhesion [GO:0034109]; muscle cell development [GO:0055001]; recognition of apoptotic cell [GO:0043654]; regulation of muscle cell differentiation [GO:0051147]; regulation of skeletal muscle tissue development [GO:0048641]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell proliferation [GO:0014841] comp65734_c0_seq1,252,46.8254,0.50891606,10,12,,4.00E-23,Q9VAC5,ADAM 17-like protease (EC 3.4.24.-),ADAM 17-like protease (EC 3.4.24.-),GO:0016021; GO:0006509; GO:0004222; GO:0008270,integral to membrane; membrane protein ectodomain proteolysis; metalloendopeptidase activity; zinc ion binding,PF16698;PF00200;PF01562;,2.00E-12,CHOYP_LOC100645870.1.1,,,,,,,ADA17_DROME,Drosophila melanogaster (Fruit fly),membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] comp65763_c0_seq1,433,44.8037,0.2844984,1,19,,6.00E-71,Q20636,Guanine nucleotide-binding protein subunit beta-2,Guanine nucleotide-binding protein subunit beta-2,GO:0007213; GO:0007212; GO:0007631; GO:0043025; GO:0008277; GO:0040012; GO:0046662; GO:0043051; GO:0032094; GO:0004871,G-protein coupled acetylcholine receptor signaling pathway; dopamine receptor signaling pathway; feeding behavior; neuronal cell body; regulation of G-protein coupled receptor protein signaling pathway; regulation of locomotion; regulation of oviposition; regulation of pharyngeal pumping; response to food; signal transducer activity,PF00400;,1.00E-79,CHOYP_LOC100368053.1.1,,,,,,,GBB2_CAEEL,Caenorhabditis elegans,dopamine receptor signaling pathway [GO:0007212]; feeding behavior [GO:0007631]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of locomotion [GO:0040012]; regulation of oviposition [GO:0046662]; regulation of pharyngeal pumping [GO:0043051]; response to food [GO:0032094] comp65765_c0_seq1,230,50.8696,0.94507923,6,0,,4.00E-12,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp65765_c1_seq1,366,45.3552,0.49350436,17,0,,5.00E-14,Q63191,Apical endosomal glycoprotein (MAM domain-containing protein 4),Apical endosomal glycoprotein (MAM domain-containing protein 4),GO:0005768; GO:0016021; GO:0015031,endosome; integral to membrane; protein transport,PF00057;PF00629;,,,,,,,,,AEGP_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp65766_c0_seq1,355,40.8451,0.61192235,8,17,,7.00E-19,Q5Y5T3,Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (DHHC-containing protein 11) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23),Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (DHHC-containing protein 11) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23),GO:0016021; GO:0072659; GO:0018345; GO:0016746; GO:0008270,"integral to membrane; protein localization to plasma membrane; protein palmitoylation; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,,,,,,,,,ZDH23_MOUSE,Mus musculus (Mouse),protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345] comp65780_c0_seq1,451,48.337,0.34251242,7,31,,2.00E-08,Q2EMV9,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6),GO:0003950; GO:0005737; GO:0003676; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleic acid binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,,,,,,,,,PAR14_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp65781_c0_seq1,368,45.3804,0.42894824,7,0,,2.00E-06,Q5ZLC8,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_CHICK,Gallus gallus (Chicken), comp65799_c0_seq1,328,36.5854,0.18462573,4,13,,1.00E-22,Q9UPT9,Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22),Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22),GO:0000124; GO:0007049; GO:0009790; GO:0043967; GO:0016578; GO:0016574; GO:0030374; GO:0045931; GO:0045893; GO:0006351; GO:0004221; GO:0006511; GO:0004843; GO:0008270,"SAGA complex; cell cycle; embryo development; histone H4 acetylation; histone deubiquitination; histone ubiquitination; ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity; zinc ion binding",PF00443;PF02148;,3.00E-29,CHOYP_UBP22.3.3,,,,,,,UBP22_HUMAN,Homo sapiens (Human),"cell cycle [GO:0007049]; embryo development [GO:0009790]; histone deubiquitination [GO:0016578]; histone H4 acetylation [GO:0043967]; histone ubiquitination [GO:0016574]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp65823_c0_seq1,393,50.3817,0.40303043,16,25,,4.00E-26,O75161,Nephrocystin-4 (Nephroretinin),Nephrocystin-4 (Nephroretinin),GO:0030036; GO:0016337; GO:0005911; GO:0005813; GO:0005929; GO:0005829; GO:0035329; GO:0016020; GO:0005932; GO:0060041; GO:0005198; GO:0005923; GO:0007632,actin cytoskeleton organization; cell-cell adhesion; cell-cell junction; centrosome; cilium; cytosol; hippo signaling cascade; membrane; microtubule basal body; retina development in camera-type eye; structural molecule activity; tight junction; visual behavior,,,,,,,,,,NPHP4_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; hippo signaling [GO:0035329]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; sperm motility [GO:0030317]; visual behavior [GO:0007632] comp65824_c0_seq1,214,32.7103,0.18282712,4,0,,3.00E-06,P20054,Protein PYR1-3 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],Protein PYR1-3 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)],GO:0044205; GO:0006207; GO:0005524; GO:0016597; GO:0004070; GO:0070409; GO:0004088; GO:0005737; GO:0004151; GO:0006543; GO:0006541; GO:0046872,'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; ATP binding; amino acid binding; aspartate carbamoyltransferase activity; carbamoyl phosphate biosynthetic process; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; cytoplasm; dihydroorotase activity; glutamine catabolic process; glutamine metabolic process; metal ion binding,PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;,,,,,,,,,PYR1_DICDI,Dictyostelium discoideum (Slime mold),'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; urea cycle [GO:0000050] comp65838_c0_seq1,307,52.1173,0.38797451,6,11,,3.00E-16,A2AKG8,Focadhesin,Focadhesin,GO:0005925; GO:0016021,focal adhesion; integral to membrane,PF11229;PF12530;,,,,,,,,,FOCAD_MOUSE,Mus musculus (Mouse), comp65855_c0_seq1,508,47.6378,0.66710612,13,6,,2.00E-23,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,7.00E-19,ruditapes_s38420,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp65862_c0_seq1,201,42.2886,0.45040134,6,15,,1.00E-10,P79745,"POU domain, class 3, transcription factor 3-B (Brain-specific homeobox/POU domain protein 1.0) (Brain-1.0) (zfBrn-1.0) (POU domain protein 1) (ZFPOU1) (POU domain protein 23) (ZP-23)","POU domain, class 3, transcription factor 3-B (Brain-specific homeobox/POU domain protein 1.0) (Brain-1.0) (zfBrn-1.0) (POU domain protein 1) (ZFPOU1) (POU domain protein 23) (ZP-23)",GO:0007275; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF00157;,,,,,,,,,P3F3B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"brain development [GO:0007420]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp65883_c0_seq1,403,39.206,0.13307065,9,0,,5.00E-22,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp65940_c0_seq1,254,33.4646,0.28912013,9,10,,,,,,,,,,,3.00E-13,ruditapes2_c1163,,,,,,, comp65983_c0_seq1,489,46.6258,0.42205172,13,10,,,,,,,,,1.00E-37,CHOYP_PHUM_PHUM044580.1.1,,,,,,,,, comp66003_c0_seq1,255,62.3529,1.10100451,0,25,,1.00E-22,Q6A6Y0,Succinyl-CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta),Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta),GO:0005524; GO:0000287; GO:0030145; GO:0004775; GO:0006099,ATP binding; magnesium ion binding; manganese ion binding; succinate-CoA ligase (ADP-forming) activity; tricarboxylic acid cycle,PF08442;PF00549;,,,,,,,,,SUCC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),tricarboxylic acid cycle [GO:0006099] comp66018_c0_seq1,526,43.1559,0.45105983,21,34,,6.00E-21,Q06187,Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase),Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase),GO:0005524; GO:0042113; GO:0050853; GO:0038095; GO:0007249; GO:0002755; GO:0002250; GO:0097190; GO:0019722; GO:0048469; GO:0031410; GO:0005829; GO:0045087; GO:0045121; GO:0007498; GO:0046872; GO:0004715; GO:0005634; GO:0005547; GO:0005886; GO:0045579; GO:0051092; GO:0002902; GO:0002721; GO:0034134; GO:0034142; GO:0038123; GO:0038124; GO:0006351,"ATP binding; B cell activation; B cell receptor signaling pathway; Fc-epsilon receptor signaling pathway; I-kappaB kinase/NF-kappaB cascade; MyD88-dependent toll-like receptor signaling pathway; adaptive immune response; apoptotic signaling pathway; calcium-mediated signaling; cell maturation; cytoplasmic vesicle; cytosol; innate immune response; membrane raft; mesoderm development; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleus; phosphatidylinositol-3,4,5-trisphosphate binding; plasma membrane; positive regulation of B cell differentiation; positive regulation of NF-kappaB transcription factor activity; regulation of B cell apoptotic process; regulation of B cell cytokine production; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor TLR1:TLR2 signaling pathway; toll-like receptor TLR6:TLR2 signaling pathway; transcription, DNA-dependent",PF00779;PF00169;PF07714;PF00017;PF00018;,,,,,,,,,BTK_HUMAN,Homo sapiens (Human),"adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]; regulation of cell proliferation [GO:0042127]; transcription, DNA-templated [GO:0006351]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" comp66046_c1_seq1,435,47.1264,0.96889401,12,17,,,,,,,,,4.00E-23,CHOYP_LOC662408.1.1,,,,,,,,, comp66047_c0_seq2,550,43.2727,0.62273286,11,15,,2.00E-32,Q9D8N3,Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A),Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A),GO:0016021,integral to membrane,PF07947;,1.00E-30,CHOYP_LOC100741906.1.1,,,,,,,TM86A_MOUSE,Mus musculus (Mouse), comp66081_c0_seq1,281,45.5516,0.20659602,9,14,,,,,,,,,3.00E-16,CHOYP_PHUM_PHUM219220.1.1,,,,,,,,, comp66082_c0_seq1,357,45.3782,1.10205575,4,25,,1.00E-13,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,,,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp66135_c0_seq1,363,35.8127,0.61486953,7,21,,,,,,,,,,,1.00E-33,ruditapes_c23312,,,,,,, comp66135_c1_seq1,355,42.8169,0.24658204,9,29,,1.00E-55,Q2NL17,Cleft lip and palate transmembrane protein 1 homolog,Cleft lip and palate transmembrane protein 1 homolog,GO:0030154; GO:0016021; GO:0007275,cell differentiation; integral to membrane; multicellular organismal development,PF05602;,1.00E-40,CHOYP_CLPT1.1.1,,,,,,,CLPT1_BOVIN,Bos taurus (Bovine),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp66138_c0_seq1,217,44.2396,0.48338055,1,9,,2.00E-18,Q5SGD7,Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (Maguin-like protein) (Parturition-related protein 4),Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (Maguin-like protein) (Parturition-related protein 4),GO:0005737; GO:0016020; GO:0070373; GO:0033137; GO:0010765,cytoplasm; membrane; negative regulation of ERK1 and ERK2 cascade; negative regulation of peptidyl-serine phosphorylation; positive regulation of sodium ion transport,PF10534;PF06663;PF00595;PF00536;,,,,,,,,,CNKR3_RAT,Rattus norvegicus (Rat),negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; positive regulation of sodium ion transport [GO:0010765] comp66164_c0_seq1,276,45.2899,0.4287982,4,8,,5.00E-31,Q1KKV8,Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog),GO:0016021; GO:0006810,integral to membrane; transport,PF05631;,8.00E-30,CHOYP_LOC574704.1.1,,,,,,,MFSD5_TAKRU,Takifugu rubripes (Japanese pufferfish) (Fugu rubripes), comp66180_c1_seq1,265,50.9434,0.75934327,5,17,,2.00E-14,Q61037,Tuberin (Tuberous sclerosis 2 protein homolog),Tuberin (Tuberous sclerosis 2 protein homolog),GO:0071889; GO:0005096; GO:0033596; GO:0030030; GO:0007507; GO:0048009; GO:0016020; GO:0032007; GO:0030178; GO:0008285; GO:0045792; GO:0014067; GO:0051898; GO:0006469; GO:0001843; GO:0005634; GO:0019902; GO:0014065; GO:0050918; GO:0006606; GO:0043491; GO:0051726; GO:0030100; GO:0046626; GO:0051056; GO:0001666,14-3-3 protein binding; GTPase activator activity; TSC1-TSC2 complex; cell projection organization; heart development; insulin-like growth factor receptor signaling pathway; membrane; negative regulation of TOR signaling cascade; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of protein kinase B signaling cascade; negative regulation of protein kinase activity; neural tube closure; nucleus; phosphatase binding; phosphatidylinositol 3-kinase cascade; positive chemotaxis; protein import into nucleus; protein kinase B signaling cascade; regulation of cell cycle; regulation of endocytosis; regulation of insulin receptor signaling pathway; regulation of small GTPase mediated signal transduction; response to hypoxia,PF11864;PF02145;PF03542;,,,,,,,,,TSC2_MOUSE,Mus musculus (Mouse),cell projection organization [GO:0030030]; cellular response to insulin stimulus [GO:0032869]; glucose import [GO:0046323]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive chemotaxis [GO:0050918]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein transport into plasma membrane raft [GO:0044861]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to hypoxia [GO:0001666] comp66183_c0_seq1,274,45.9854,0.21127042,4,19,,1.00E-37,O17214,"Probable fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)","Probable fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)",GO:0004333; GO:0006106; GO:0005739; GO:0006099; GO:0045239,fumarate hydratase activity; fumarate metabolic process; mitochondrion; tricarboxylic acid cycle; tricarboxylic acid cycle enzyme complex,PF10415;PF00206;,,,,,,,,,FUMH_CAEEL,Caenorhabditis elegans,fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099] comp66201_c0_seq1,234,41.0256,0.31264429,5,17,,2.00E-10,A4FUP9,Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-),Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-),GO:0009058; GO:0005576; GO:0016757,"biosynthetic process; extracellular region; transferase activity, transferring glycosyl groups",PF00534;,,,,,,,,,GL1D1_MOUSE,Mus musculus (Mouse), comp66203_c0_seq1,361,42.3823,1.17774876,0,36,,2.00E-30,P55214,"Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11; Caspase-7, N-terminally processed]",Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11],GO:0006915; GO:0004197; GO:0005737; GO:0006508,apoptotic process; cysteine-type endopeptidase activity; cytoplasm; proteolysis,,,,,,,,,,CASP7_MESAU,Mesocricetus auratus (Golden hamster),apoptotic process [GO:0006915] comp66244_c1_seq1,238,48.7395,0.36612166,6,14,,5.00E-12,Q9D9Q0,Leucine-rich repeat-containing protein 69,Leucine-rich repeat-containing protein 69,,,PF00560;PF13855;,,,,,,,,,LRC69_MOUSE,Mus musculus (Mouse), comp66281_c0_seq1,222,39.6396,0.61433753,2,0,,2.00E-07,Q68CJ6,Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center),GO:0005525; GO:0006184; GO:0003924; GO:0005634,GTP binding; GTP catabolic process; GTPase activity; nucleus,PF00350;,,,,,,,,,SLIP_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp66338_c0_seq1,553,50.8137,0.31357517,11,28,,2.00E-28,P09086,"POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)","POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)",GO:0048469; GO:0005737; GO:0006959; GO:0002380; GO:0002335; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006366,"cell maturation; cytoplasm; humoral immune response; immunoglobulin secretion involved in immune response; mature B cell differentiation; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter",PF00046;PF00157;,2.00E-34,CHOYP_PO2F1.1.1,,,,,,,PO2F2_HUMAN,Homo sapiens (Human),cell maturation [GO:0048469]; humoral immune response [GO:0006959]; immunoglobulin secretion involved in immune response [GO:0002380]; mature B cell differentiation [GO:0002335]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription from RNA polymerase II promoter [GO:0006366] comp66375_c0_seq1,224,41.9643,0.10204285,0,9,,4.00E-21,P36406,E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23),E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23),GO:0019003; GO:0005525; GO:0003924; GO:0000139; GO:0008047; GO:0005765; GO:0019048; GO:0005634; GO:0007264; GO:0004842; GO:0008270,GDP binding; GTP binding; GTPase activity; Golgi membrane; enzyme activator activity; lysosomal membrane; modulation by virus of host morphology or physiology; nucleus; small GTPase mediated signal transduction; ubiquitin-protein ligase activity; zinc ion binding,PF00025;PF00643;PF14634;,,,,,,,,,TRI23_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264]; viral process [GO:0016032] comp66420_c0_seq1,264,50,0.91338627,0,29,,4.00E-27,P70665,Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit],Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit],GO:0004091; GO:0005764; GO:0001681,carboxylesterase activity; lysosome; sialate O-acetylesterase activity,PF03629;,,,,,,,,,SIAE_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975]; regulation of immune system process [GO:0002682] comp66423_c0_seq1,707,46.1103,0.58704373,8,39,,3.00E-50,P45447,Ecdysone-induced protein 78C (DR-78) (Nuclear receptor subfamily 1 group E member 1),Ecdysone-induced protein 78C (DR-78) (Nuclear receptor subfamily 1 group E member 1),GO:0004879; GO:0005634; GO:0043565; GO:0003707; GO:0008270,ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,2.00E-43,CHOYP_LOC100161053.1.1,,,,,,,E78C_DROME,Drosophila melanogaster (Fruit fly),"instar larval or pupal development [GO:0002165]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]" comp66428_c0_seq2,649,41.2943,0.40395576,5,26,,2.00E-25,Q9BQI3,Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase),Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase),GO:0005524; GO:0005737; GO:0004694; GO:0020037; GO:0008285; GO:0046986; GO:0045993; GO:0046777; GO:0042803; GO:0046501; GO:0010999; GO:0009605; GO:0006950,ATP binding; cytoplasm; eukaryotic translation initiation factor 2alpha kinase activity; heme binding; negative regulation of cell proliferation; negative regulation of hemoglobin biosynthetic process; negative regulation of translational initiation by iron; protein autophosphorylation; protein homodimerization activity; protoporphyrinogen IX metabolic process; regulation of eIF2 alpha phosphorylation by heme; response to external stimulus; response to stress,PF00069;,8.00E-28,CHOYP_EIF2AK1.1.1,,,,,,,E2AK1_HUMAN,Homo sapiens (Human),acute inflammatory response [GO:0002526]; iron ion homeostasis [GO:0055072]; macrophage differentiation [GO:0030225]; negative regulation of cell proliferation [GO:0008285]; negative regulation of hemoglobin biosynthetic process [GO:0046986]; negative regulation of translational initiation by iron [GO:0045993]; phagocytosis [GO:0006909]; protein autophosphorylation [GO:0046777]; protoporphyrinogen IX metabolic process [GO:0046501]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]; response to external stimulus [GO:0009605]; response to stress [GO:0006950] comp66455_c1_seq1,350,44.2857,0.44318544,8,18,,4.00E-06,Q502M6,Ankyrin repeat domain-containing protein 29,Ankyrin repeat domain-containing protein 29,,,PF00023;PF12796;,,,,,,,,,ANR29_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp66550_c0_seq1,225,53.7778,0.68148276,1,13,,5.00E-16,Q5RFF0,Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20),GO:0016323; GO:0030154; GO:0016021; GO:0006811; GO:0007275; GO:0007283; GO:0005215,basolateral plasma membrane; cell differentiation; integral to membrane; ion transport; multicellular organismal development; spermatogenesis; transporter activity,PF07648;PF03137;,4.00E-26,CHOYP_MYSP.9.9,,,,,,,SO4C1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cell differentiation [GO:0030154]; ion transport [GO:0006811]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp66562_c0_seq1,430,42.5581,0.88920384,17,3,,8.00E-28,Q5T0B9,Zinc finger protein 362,Zinc finger protein 362,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN362_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp66563_c0_seq1,207,62.3188,0.76322721,5,2,,8.00E-10,Q9KBR3,Glycerol-1-phosphate dehydrogenase [NAD(P)+] (G1P dehydrogenase) (G1PDH) (EC 1.1.1.261) (Enantiomeric glycerophosphate synthase) (sn-glycerol-1-phosphate dehydrogenase),Glycerol-1-phosphate dehydrogenase [NAD(P)+] (G1P dehydrogenase) (G1PDH) (EC 1.1.1.261) (Enantiomeric glycerophosphate synthase) (sn-glycerol-1-phosphate dehydrogenase),GO:0005737; GO:0050492; GO:0046872; GO:0008654,cytoplasm; glycerol-1-phosphate dehydrogenase [NAD(P)+] activity; metal ion binding; phospholipid biosynthetic process,PF13685;,,,,,,,,,G1PDH_BACHD,Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125),phospholipid biosynthetic process [GO:0008654] comp66587_c0_seq2,370,43.2432,0.8700814,2,25,,2.00E-45,P43003,Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3),Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3),GO:0070779; GO:0051938; GO:0005313; GO:0031223; GO:0048667; GO:0042995; GO:0009986; GO:0021545; GO:0043205; GO:0009449; GO:0016595; GO:0006537; GO:0005314; GO:0016021; GO:0050885; GO:0043025; GO:0001504; GO:0005886; GO:0050806; GO:0046677; GO:0042493; GO:0009416; GO:0009611; GO:0007605; GO:0017153,D-aspartate import; L-glutamate import; L-glutamate transmembrane transporter activity; auditory behavior; cell morphogenesis involved in neuron differentiation; cell projection; cell surface; cranial nerve development; fibril; gamma-aminobutyric acid biosynthetic process; glutamate binding; glutamate biosynthetic process; high-affinity glutamate transmembrane transporter activity; integral to membrane; neuromuscular process controlling balance; neuronal cell body; neurotransmitter uptake; plasma membrane; positive regulation of synaptic transmission; response to antibiotic; response to drug; response to light stimulus; response to wounding; sensory perception of sound; sodium:dicarboxylate symporter activity,PF00375;,1.00E-15,CHOYP_LOC100691601.2.2,,,,,,,EAA1_HUMAN,Homo sapiens (Human),auditory behavior [GO:0031223]; cell morphogenesis involved in neuron differentiation [GO:0048667]; chemical synaptic transmission [GO:0007268]; cranial nerve development [GO:0021545]; D-aspartate import [GO:0070779]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; glutamate biosynthetic process [GO:0006537]; glutamate secretion [GO:0014047]; ion transport [GO:0006811]; L-glutamate import [GO:0051938]; malate-aspartate shuttle [GO:0043490]; mitophagy in response to mitochondrial depolarization [GO:0098779]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter uptake [GO:0001504]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of synaptic transmission [GO:0050806]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to light stimulus [GO:0009416]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; xenophagy [GO:0098792] comp6661_c0_seq1,367,40.8719,0.53488769,16,0,,1.00E-11,P08603,Complement factor H (H factor 1),Complement factor H (H factor 1),GO:0006956; GO:0006957; GO:0005615; GO:0043395; GO:0008201; GO:0045087; GO:0030449,"complement activation; complement activation, alternative pathway; extracellular space; heparan sulfate proteoglycan binding; heparin binding; innate immune response; regulation of complement activation",PF00084;,,,,,,,,,CFAH_HUMAN,Homo sapiens (Human),"complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]" comp66659_c0_seq1,708,45.904,0.64709591,45,11,,2.00E-42,O94915,Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein),Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein),GO:0006355; GO:0006351,"regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14225;PF14228;PF14222;,2.00E-55,CHOYP_LOC657755.1.1,,,,,,,FRYL_HUMAN,Homo sapiens (Human),"actin filament reorganization [GO:0090527]; cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp66664_c0_seq1,326,45.3988,0.77687135,4,20,,3.00E-39,O15439,Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B),GO:0016404; GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886; GO:0030168; GO:0002576; GO:0031088; GO:0055085,"15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; platelet activation; platelet degranulation; platelet dense granule membrane; transmembrane transport",PF00664;PF00005;,4.00E-28,CHOYP_MRP4.1.3,,,,,,,MRP4_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085] comp66699_c0_seq1,433,39.261,0.84202223,11,14,,6.00E-13,Q503R4,Kelch-like protein 36,Kelch-like protein 36,GO:0016567,protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH36_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp66724_c0_seq1,781,46.3508,0.88361727,12,69,,2.00E-58,O70531,Sulfate transporter (Diastrophic dysplasia protein homolog) (Solute carrier family 26 member 2),Sulfate transporter (Diastrophic dysplasia protein homolog) (Solute carrier family 26 member 2),GO:0016021; GO:0001503; GO:0008271; GO:0015116; GO:0008272,integral to membrane; ossification; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; sulfate transport,PF01740;PF00916;,1.00E-39,CHOYP_LOC100552593.3.3,,,,,,,S26A2_RAT,Rattus norvegicus (Rat),bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; ossification [GO:0001503]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sulfate transport [GO:0008272] comp66734_c0_seq1,224,40.625,0.97828037,0,6,,6.00E-18,P29074,Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1),GO:0005737; GO:0005856; GO:0009898; GO:0004726,cytoplasm; cytoskeleton; internal side of plasma membrane; non-membrane spanning protein tyrosine phosphatase activity,PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;,3.00E-28,CHOYP_PTN4.1.2,,,,,,,PTN4_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470] comp66740_c0_seq1,488,43.8525,0.65726082,18,34,,1.00E-33,E1C2Z0,Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),GO:0035101; GO:0042555; GO:0000724; GO:0043596; GO:0031297,FACT complex; MCM complex; double-strand break repair via homologous recombination; nuclear replication fork; replication fork processing,PF14911;PF14910;,,,,,,,,,MMS22_CHICK,Gallus gallus (Chicken),double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] comp66756_c0_seq1,365,46.5753,0.355836,5,8,,7.00E-36,Q9D9V7,Protein DENND6B (DENN domain-containing protein 6B),Protein DENND6B (DENN domain-containing protein 6B),GO:0017112; GO:0055037,Rab guanyl-nucleotide exchange factor activity; recycling endosome,PF09794;,9.00E-37,CHOYP_LOC100372051.1.1,,,,,,,F116B_MOUSE,Mus musculus (Mouse),positive regulation of GTPase activity [GO:0043547] comp66768_c0_seq1,339,46.6077,0.11039057,26,0,,1.00E-06,Q5TH69,Brefeldin A-inhibited guanine nucleotide-exchange protein 3,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3),GO:0005086; GO:0016021; GO:0010923; GO:0032012; GO:0005802; GO:0016192,ARF guanyl-nucleotide exchange factor activity; integral to membrane; negative regulation of phosphatase activity; regulation of ARF protein signal transduction; trans-Golgi network; vesicle-mediated transport,PF16213;PF09324;,9.00E-24,CHOYP_BIG3.1.1,,,,,,,BIG3_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012] comp66806_c0_seq1,239,44.7699,0.45249661,7,12,,7.00E-31,Q3UPY5,Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),Beta-galactosidase-1-like protein 2 (EC 3.2.1.-),GO:0004565; GO:0005975; GO:0005576,beta-galactosidase activity; carbohydrate metabolic process; extracellular region,PF01301;,1.00E-20,CHOYP_GLB1L2.1.1,,,,,,,GLBL2_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975] comp66818_c0_seq1,203,57.6355,0.99941188,5,2,,7.00E-10,P0AAE0,D-serine/D-alanine/glycine transporter,D-serine/D-alanine/glycine transporter,GO:0042944; GO:0042945; GO:0015180; GO:0042895; GO:0001761; GO:0015187; GO:0016021; GO:0005886,D-alanine transmembrane transporter activity; D-serine transmembrane transporter activity; L-alanine transmembrane transporter activity; antibiotic transporter activity; beta-alanine transmembrane transporter activity; glycine transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,CYCA_ECOLI,Escherichia coli (strain K12),antibiotic transport [GO:0042891]; beta-alanine transport [GO:0001762]; D-alanine transport [GO:0042941]; D-serine transport [GO:0042942]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808] comp66828_c1_seq1,337,62.6113,0.84313381,0,23,,4.00E-06,P0AAV4,Uncharacterized protein YbgJ,Uncharacterized protein YbgJ,GO:0003755; GO:0006457; GO:0000413,peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF02682;,,,,,,,,,YBGJ_ECOLI,Escherichia coli (strain K12), comp66835_c0_seq1,276,45.6522,0.14046838,7,11,,3.00E-10,P31696,Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)],GO:0007213; GO:0030548; GO:0005605; GO:0005509; GO:0030154; GO:0030054; GO:0035374; GO:0002162; GO:0043395; GO:0008201; GO:0016021; GO:0043236; GO:0007275; GO:0005886; GO:0032321; GO:0051491; GO:0045887; GO:0045944; GO:0043113; GO:0033691; GO:0045202; GO:0030297,G-protein coupled acetylcholine receptor signaling pathway; acetylcholine receptor regulator activity; basal lamina; calcium ion binding; cell differentiation; cell junction; chondroitin sulfate binding; dystroglycan binding; heparan sulfate proteoglycan binding; heparin binding; integral to membrane; laminin binding; multicellular organismal development; plasma membrane; positive regulation of Rho GTPase activity; positive regulation of filopodium assembly; positive regulation of synaptic growth at neuromuscular junction; positive regulation of transcription from RNA polymerase II promoter; receptor clustering; sialic acid binding; synapse; transmembrane receptor protein tyrosine kinase activator activity,PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;,,,,,,,,,AGRIN_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113] comp66875_c1_seq1,382,48.4293,0.44764215,21,6,,2.00E-64,Q8VDG6,Mitogen-activated protein kinase kinase kinase MLK4 (EC 2.7.11.25) (Mixed lineage kinase 4),Mitogen-activated protein kinase kinase kinase MLK4 (EC 2.7.11.25) (Mixed lineage kinase 4),GO:0005524; GO:0004709; GO:0000165; GO:0000186; GO:0018108; GO:0004713,ATP binding; MAP kinase kinase kinase activity; MAPK cascade; activation of MAPKK activity; peptidyl-tyrosine phosphorylation; protein tyrosine kinase activity,PF07714;PF14604;,4.00E-60,CHOYP_LOC100366440.1.1,,,,,,,M3KL4_MOUSE,Mus musculus (Mouse), comp66877_c0_seq1,205,44.878,0.09777167,6,0,,3.00E-13,A3A9H6,Probable ascorbate-specific transmembrane electron transporter 1 (EC 1.-.-.-) (Cytochrome b561-1),Probable ascorbate-specific transmembrane electron transporter 1 (EC 1.-.-.-) (Cytochrome b561-1),GO:0016021; GO:0046872; GO:0016491,integral to membrane; metal ion binding; oxidoreductase activity,PF03188;,,,,,,,,,ACET1_ORYSJ,Oryza sativa subsp. japonica (Rice),oxidation-reduction process [GO:0055114] comp66877_c1_seq1,335,44.1791,0.24765284,4,6,,1.00E-20,P34465,Putative cytochrome b561 (Cytochrome b-561),Putative cytochrome b561 (Cytochrome b-561),GO:0016021; GO:0046872; GO:0055114,integral to membrane; metal ion binding; oxidation-reduction process,PF03188;,3.00E-24,CHOYP_LOC100693612.1.1,,,,,,,CY561_CAEEL,Caenorhabditis elegans,oxidation-reduction process [GO:0055114] comp66877_c2_seq1,237,51.0549,0.39017088,4,23,,1.00E-11,Q53TN4,Cytochrome b reductase 1 (EC 1.-.-.-) (Duodenal cytochrome b) (Ferric-chelate reductase 3),Cytochrome b reductase 1 (EC 1.-.-.-) (Duodenal cytochrome b) (Ferric-chelate reductase 3),GO:0031526; GO:0006879; GO:0000293; GO:0016021; GO:0046872; GO:0005886; GO:0010039; GO:0055085,brush border membrane; cellular iron ion homeostasis; ferric-chelate reductase activity; integral to membrane; metal ion binding; plasma membrane; response to iron ion; transmembrane transport,PF03188;,,,,,,,,,CYBR1_HUMAN,Homo sapiens (Human),cellular iron ion homeostasis [GO:0006879]; response to iron ion [GO:0010039] comp66886_c0_seq1,277,46.5704,0.67509379,5,8,,5.00E-17,Q15413,Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor),GO:0005509; GO:0006874; GO:0071318; GO:0071313; GO:0071277; GO:0071286; GO:0016021; GO:0030314; GO:0051289; GO:0005219; GO:0033017; GO:0006941,calcium ion binding; cellular calcium ion homeostasis; cellular response to ATP; cellular response to caffeine; cellular response to calcium ion; cellular response to magnesium ion; integral to membrane; junctional membrane complex; protein homotetramerization; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane; striated muscle contraction,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,2.00E-25,CHOYP_LOC100643070.1.1,,,,,,,RYR3_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; ion transmembrane transport [GO:0034220]; protein homotetramerization [GO:0051289]; regulation of cardiac conduction [GO:1903779] comp66895_c0_seq1,211,43.128,0.83139122,3,12,,4.00E-06,Q96PZ7,CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1),GO:0016021,integral to membrane,PF00431;PF00084;,,,,,,,,,CSMD1_HUMAN,Homo sapiens (Human), comp6690_c0_seq1,243,40.7407,0.60050238,6,0,,1.00E-26,P23338,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase),UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase),GO:0003975; GO:0005789; GO:0016021; GO:0008963; GO:0006486; GO:0016757,"UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity; endoplasmic reticulum membrane; integral to membrane; phospho-N-acetylmuramoyl-pentapeptide-transferase activity; protein glycosylation; transferase activity, transferring glycosyl groups",PF00953;,4.00E-39,CHOYP_LOC100368253.1.1,,,,,,,GPT_CRILO,Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster),protein glycosylation [GO:0006486] comp66925_c0_seq1,251,44.6215,0.91941758,4,10,,6.00E-22,Q5R9C2,Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3),Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3),GO:0005887; GO:0015820; GO:0005328; GO:0005298,integral to plasma membrane; leucine transport; neurotransmitter:sodium symporter activity; proline:sodium symporter activity,PF00209;,4.00E-14,CHOYP_SMP_028690.1.1,,,,,,,S6A15_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824] comp66936_c0_seq1,226,44.6903,0.71385045,1,1,,1.00E-06,Q6XHB2,Probable serine/threonine-protein kinase roco4 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 4),Probable serine/threonine-protein kinase roco4 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 4),GO:0005524; GO:0005525; GO:0005829; GO:0004672; GO:0004674; GO:0031153; GO:0007264; GO:0031150,ATP binding; GTP binding; cytosol; protein kinase activity; protein serine/threonine kinase activity; slug development involved in sorocarp development; small GTPase mediated signal transduction; sorocarp stalk development,PF16095;PF07714;PF08477;,3.00E-28,CHOYP_TRIADDRAFT_57945.3.3,,,,,,,ROCO4_DICDI,Dictyostelium discoideum (Slime mold),slug development involved in sorocarp development [GO:0031153]; small GTPase mediated signal transduction [GO:0007264]; sorocarp stalk development [GO:0031150] comp66957_c1_seq1,245,47.3469,0.58572404,6,0,,,,,,,,,7.00E-11,CHOYP_BRAFLDRAFT_117157.3.3,,,,,,,,, comp66962_c0_seq1,404,38.6139,0.13455232,1,13,,4.00E-23,Q5RAG4,RING finger and transmembrane domain-containing protein 2 (Transmembrane protein 118),RING finger and transmembrane domain-containing protein 2 (Transmembrane protein 118),GO:0016021; GO:0008270,integral to membrane; zinc ion binding,,,,5.00E-19,ruditapes_c24219,,,,,RNFT2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp66968_c0_seq1,236,47.0339,0.63033047,7,13,,4.00E-08,Q969K4,Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein),Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein),GO:0005737; GO:0005730; GO:0005886; GO:0003746,cytoplasm; nucleolus; plasma membrane; translation elongation factor activity,PF12796;PF00651;,,,,,,,,,ABTB1_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp66975_c0_seq1,432,44.4444,0.57991382,12,17,,1.00E-53,Q6GQ76,Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2),GO:0006370; GO:0097309; GO:0004483; GO:0003676; GO:0005634,7-methylguanosine mRNA capping; cap1 mRNA methylation; mRNA (nucleoside-2'-O-)-methyltransferase activity; nucleic acid binding; nucleus,PF01728;PF01585;,4.00E-30,CHOYP_MTR1.1.1,,,,,,,MTR1_XENLA,Xenopus laevis (African clawed frog),7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009] comp66980_c0_seq1,231,68.3983,0.85844595,0,18,,8.00E-09,Q93WI0,Rhodanese-like/PpiC domain-containing protein 12 (Sulfurtransferase 12) (AtStr12),"Rhodanese-like/PpiC domain-containing protein 12, chloroplastic (Sulfurtransferase 12) (AtStr12)",GO:0009507; GO:0016853,chloroplast; isomerase activity,PF00581;,,,,,,,,,STR12_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to cytokinin [GO:0009735] comp66998_c0_seq1,791,43.9949,0.83845703,24,38,,5.00E-09,P05084,Protein hunchback,Protein hunchback,GO:0000980; GO:0003705; GO:0007355; GO:0007427; GO:0007402; GO:0046872; GO:0001763; GO:0000122; GO:0007400; GO:0005634; GO:0045944; GO:0035289; GO:0040034; GO:0044324; GO:0007431; GO:0007362; GO:0008293; GO:0035290; GO:0007419,"RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; anterior region determination; epithelial cell migration, open tracheal system; ganglion mother cell fate determination; metal ion binding; morphogenesis of a branching structure; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleus; positive regulation of transcription from RNA polymerase II promoter; posterior head segmentation; regulation of development, heterochronic; regulation of transcription involved in anterior/posterior axis specification; salivary gland development; terminal region determination; torso signaling pathway; trunk segmentation; ventral cord development",,,,,,,,,,HUNB_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior axis specification, embryo [GO:0008595]; anterior region determination [GO:0007355]; epithelial cell migration, open tracheal system [GO:0007427]; ganglion mother cell fate determination [GO:0007402]; generation of neurons [GO:0048699]; morphogenesis of a branching structure [GO:0001763]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; open tracheal system development [GO:0007424]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; posterior head segmentation [GO:0035289]; regulation of development, heterochronic [GO:0040034]; regulation of transcription involved in anterior/posterior axis specification [GO:0044324]; salivary gland development [GO:0007431]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; transcription, DNA-templated [GO:0006351]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]" comp66998_c1_seq1,1060,47.6415,0.48719088,53,36,,1.00E-28,Q8TC21,Zinc finger protein 596,Zinc finger protein 596,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN596_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp67027_c1_seq1,201,44.2786,0.30919133,2,0,,,,,,,,,8.00E-22,CHOYP_LOC101171601.1.1,,,,,,,,, comp67069_c0_seq1,841,44.1141,0.36800751,32,17,,2.00E-49,P11717,Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222),GO:0009986; GO:0030139; GO:0005768; GO:0001948; GO:0005010; GO:0005887; GO:0005765; GO:0005537; GO:0005641; GO:0051219; GO:0006898; GO:0030140; GO:0005215,cell surface; endocytic vesicle; endosome; glycoprotein binding; insulin-like growth factor-activated receptor activity; integral to plasma membrane; lysosomal membrane; mannose binding; nuclear envelope lumen; phosphoprotein binding; receptor-mediated endocytosis; trans-Golgi network transport vesicle; transporter activity,PF00878;PF00040;,,,,,,,,,MPRI_HUMAN,Homo sapiens (Human),liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] comp67087_c0_seq1,327,63.3028,1.30827434,0,18,,5.00E-38,O33062,Putative phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT),Putative phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT),GO:0006564; GO:0004648; GO:0005737; GO:0030170; GO:0008615,L-serine biosynthetic process; O-phospho-L-serine:2-oxoglutarate aminotransferase activity; cytoplasm; pyridoxal phosphate binding; pyridoxine biosynthetic process,PF00266;,,,,,,,,,SERC_MYCLE,Mycobacterium leprae (strain TN),L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615] comp67088_c0_seq3,270,43.3333,0.72806969,0,0,,3.00E-08,P11584,Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C),Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C),GO:0007015; GO:0007475; GO:0007411; GO:0009925; GO:0007298; GO:0016339; GO:0016340; GO:0050839; GO:0031252; GO:0007417; GO:0008340; GO:0007391; GO:0035001; GO:0007427; GO:0007629; GO:0005925; GO:0007377; GO:0030718; GO:0035099; GO:0007157; GO:0048803; GO:0008305; GO:0007229; GO:0007508; GO:0016328; GO:0035160; GO:0007494; GO:0016203; GO:0030336; GO:0003344; GO:0004872; GO:0008360; GO:0051492; GO:0007431; GO:0007608; GO:0006930; GO:0007426; GO:0007601,"actin filament organization; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; basal plasma membrane; border follicle cell migration; calcium-dependent cell-cell adhesion; calcium-dependent cell-matrix adhesion; cell adhesion molecule binding; cell leading edge; central nervous system development; determination of adult lifespan; dorsal closure; dorsal trunk growth, open tracheal system; epithelial cell migration, open tracheal system; flight behavior; focal adhesion; germ-band extension; germ-line stem cell maintenance; hemocyte migration; heterophilic cell-cell adhesion; imaginal disc-derived male genitalia morphogenesis; integrin complex; integrin-mediated signaling pathway; larval heart development; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; midgut development; muscle attachment; negative regulation of cell migration; pericardium morphogenesis; receptor activity; regulation of cell shape; regulation of stress fiber assembly; salivary gland development; sensory perception of smell; substrate-dependent cell migration, cell extension; tracheal outgrowth, open tracheal system; visual perception",PF07974;PF08725;PF07965;PF00362;,,,,,,,,,ITBX_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-dependent cell-matrix adhesion [GO:0016340]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; central nervous system development [GO:0007417]; central nervous system morphogenesis [GO:0021551]; determination of adult lifespan [GO:0008340]; dorsal closure [GO:0007391]; dorsal trunk growth, open tracheal system [GO:0035001]; epithelial cell migration, open tracheal system [GO:0007427]; flight behavior [GO:0007629]; germ-band extension [GO:0007377]; germ-line stem cell population maintenance [GO:0030718]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; integrin-mediated signaling pathway [GO:0007229]; larval heart development [GO:0007508]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; negative regulation of cell migration [GO:0030336]; pericardium morphogenesis [GO:0003344]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; tracheal outgrowth, open tracheal system [GO:0007426]; visual perception [GO:0007601]" comp67095_c0_seq1,447,41.1633,0.22335896,8,14,,2.00E-51,Q8WZA0,Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein),Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein),GO:0007417; GO:0010212,central nervous system development; response to ionizing radiation,PF06384;,2.00E-52,CHOYP_LZIC.1.1,,,,,,,LZIC_HUMAN,Homo sapiens (Human),response to ionizing radiation [GO:0010212] comp67124_c0_seq1,373,43.1635,0.29109798,13,19,,3.00E-09,Q98943,Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12],GO:0006915; GO:0004197; GO:0005622; GO:0006508; GO:0042981,apoptotic process; cysteine-type endopeptidase activity; intracellular; proteolysis; regulation of apoptotic process,PF00619;,,,,,,,,,CASP2_CHICK,Gallus gallus (Chicken),regulation of apoptotic process [GO:0042981] comp67217_c0_seq1,402,44.5274,1.00649973,4,0,,2.00E-12,Q7TN88,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005262; GO:0005509; GO:0030246; GO:0050982; GO:0016021; GO:0016020; GO:0007218,calcium channel activity; calcium ion binding; carbohydrate binding; detection of mechanical stimulus; integral to membrane; membrane; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_MOUSE,Mus musculus (Mouse),detection of mechanical stimulus [GO:0050982] comp67217_c1_seq1,323,45.2012,0.85909914,16,0,,3.00E-12,Q7Z442,Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2),GO:0005509; GO:0030246; GO:0016021; GO:0006811; GO:0007218,calcium ion binding; carbohydrate binding; integral to membrane; ion transport; neuropeptide signaling pathway,PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;,,,,,,,,,PK1L2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982] comp67222_c0_seq1,483,39.7516,0.63082708,21,10,,1.00E-06,P03364,Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)],Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)],GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0075713; GO:0090305; GO:0004523; GO:0046718; GO:0008270,DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; establishment of integrated proviral latency; nucleic acid phosphodiester bond hydrolysis; ribonuclease H activity; viral entry into host cell; zinc ion binding,PF00552;PF02022;PF00075;PF00665;PF00078;PF06817;,1.00E-12,CHOYP_LOC100493440.1.2,,,,,,,POL_SMRVH,Squirrel monkey retrovirus (SMRV-H) (SMRV-HLB),DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718] comp67255_c0_seq1,285,44.2105,0.67294946,2,15,,5.00E-13,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp67265_c1_seq1,275,40.7273,0.53077625,6,2,,2.00E-23,Q8WPJ2,"Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)","Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)",GO:0046355; GO:0016985,"mannan catabolic process; mannan endo-1,4-beta-mannosidase activity",PF00150;,,,,,,,,,MANA_MYTED,Mytilus edulis (Blue mussel),mannan catabolic process [GO:0046355] comp67266_c0_seq1,442,48.19,0.28739721,12,13,,2.00E-23,Q6NY73,Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B),Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B),GO:0007155; GO:0016020; GO:0005578; GO:0005044,cell adhesion; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00651;PF00530;,,,,,,,,,L3BPB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155] comp67272_c0_seq1,245,46.1224,0.69623801,9,14,,8.00E-11,Q9WTN5,Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1),Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1),GO:0072345; GO:0010008; GO:0016021; GO:0005765; GO:0005244,NAADP-sensitive calcium-release channel activity; endosome membrane; integral to membrane; lysosomal membrane; voltage-gated ion channel activity,PF00520;,1.00E-19,CHOYP_LOC567534.1.1,,,,,,,TPC1_RAT,Rattus norvegicus (Rat),membrane depolarization during action potential [GO:0086010] comp67273_c0_seq1,301,36.5449,0.82066123,8,16,,4.00E-08,Q5XIH9,4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1),4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1),GO:0003868; GO:0009072; GO:0046872,4-hydroxyphenylpyruvate dioxygenase activity; aromatic amino acid family metabolic process; metal ion binding,,,,,,,,,,HPDL_RAT,Rattus norvegicus (Rat),aromatic amino acid family metabolic process [GO:0009072] comp67276_c0_seq1,252,42.4603,0.35434732,1,24,,3.00E-22,Q70EL4,Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.4.19.12) (Deubiquitinating enzyme 43) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43),Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.4.19.12) (Deubiquitinating enzyme 43) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP43_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511] comp67278_c0_seq1,343,43.7318,0.24677398,0,0,,,,,,,,,4.00E-15,CHOYP_LOC591009.1.1,,,,,,,,, comp67278_c0_seq2,470,44.8936,0.25556274,1,16,,3.00E-16,Q80U56,Late secretory pathway protein AVL9 homolog,Late secretory pathway protein AVL9 homolog,GO:0016477; GO:0016021; GO:0055037,cell migration; integral to membrane; recycling endosome,PF09794;,6.00E-15,CHOYP_LOC591009.1.1,,,,,,,AVL9_MOUSE,Mus musculus (Mouse),cell migration [GO:0016477] comp67290_c0_seq1,316,36.0759,0.49026164,3,19,,1.00E-27,Q147U1,Zinc finger protein 846,Zinc finger protein 846,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN846_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp67290_c0_seq2,220,37.2727,0.92914833,7,24,,1.00E-20,P18146,Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24),Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24),GO:0030509; GO:0001077; GO:0000979; GO:0030217; GO:0071236; GO:0071320; GO:0035690; GO:0071372; GO:0071480; GO:0071371; GO:0071363; GO:0071504; GO:0071455; GO:0071456; GO:0032869; GO:0071317; GO:0071260; GO:0071506; GO:0071383; GO:0007623; GO:0005737; GO:0003690; GO:0072110; GO:0070498; GO:0007611; GO:0060291; GO:0046872; GO:0043066; GO:0090090; GO:0000122; GO:0005654; GO:0048709; GO:0072303; GO:0043525; GO:0045944; GO:0048169; GO:0033233; GO:0001975; GO:0034465; GO:0042220; GO:0051602; GO:0045471; GO:0009749; GO:0071873; GO:0031667; GO:0003700; GO:0035914; GO:0006366; GO:0000976; GO:0060337,BMP signaling pathway; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; T cell differentiation; cellular response to antibiotic; cellular response to cAMP; cellular response to drug; cellular response to follicle-stimulating hormone stimulus; cellular response to gamma radiation; cellular response to gonadotropin stimulus; cellular response to growth factor stimulus; cellular response to heparin; cellular response to hyperoxia; cellular response to hypoxia; cellular response to insulin stimulus; cellular response to isoquinoline alkaloid; cellular response to mechanical stimulus; cellular response to mycophenolic acid; cellular response to steroid hormone stimulus; circadian rhythm; cytoplasm; double-stranded DNA binding; glomerular mesangial cell proliferation; interleukin-1-mediated signaling pathway; learning or memory; long-term synaptic potentiation; metal ion binding; negative regulation of apoptotic process; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleoplasm; oligodendrocyte differentiation; positive regulation of glomerular metanephric mesangial cell proliferation; positive regulation of neuron apoptotic process; positive regulation of transcription from RNA polymerase II promoter; regulation of long-term neuronal synaptic plasticity; regulation of protein sumoylation; response to amphetamine; response to carbon monoxide; response to cocaine; response to electrical stimulus; response to ethanol; response to glucose stimulus; response to norepinephrine stimulus; response to nutrient levels; sequence-specific DNA binding transcription factor activity; skeletal muscle cell differentiation; transcription from RNA polymerase II promoter; transcription regulatory region sequence-specific DNA binding; type I interferon-mediated signaling pathway,PF11914;PF11928;,,,,,,,,,EGR1_HUMAN,Homo sapiens (Human),"BMP signaling pathway [GO:0030509]; cellular response to gamma radiation [GO:0071480]; cellular response to heparin [GO:0071504]; cellular response to mycophenolic acid [GO:0071506]; glomerular mesangial cell proliferation [GO:0072110]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of glomerular metanephric mesangial cell proliferation [GO:0072303]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of protein sumoylation [GO:0033233]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; skeletal muscle cell differentiation [GO:0035914]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366]; type I interferon signaling pathway [GO:0060337]" comp67292_c0_seq1,304,62.1711,0.88822646,1,5,,8.00E-25,P22554,Cytochrome c biogenesis protein ccsA,Cytochrome c biogenesis protein CcsA,GO:0009535; GO:0017004; GO:0016021; GO:0008535,chloroplast thylakoid membrane; cytochrome complex assembly; integral to membrane; respiratory chain complex IV assembly,PF01578;,,,,,,,,,CCSA_GUITH,Guillardia theta (Cryptomonas phi),cytochrome complex assembly [GO:0017004] comp6729_c0_seq1,201,40.2985,0.66014706,5,0,,2.00E-08,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp67314_c0_seq1,368,42.663,0.80217984,4,21,,2.00E-37,Q80U87,Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8),GO:0007265; GO:0007049; GO:0005829; GO:0007032; GO:0031313; GO:0030496; GO:0005634; GO:0005886; GO:0016579; GO:0004221; GO:0006511; GO:0004843,Ras protein signal transduction; cell cycle; cytosol; endosome organization; extrinsic to endosome membrane; midbody; nucleus; plasma membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF00581;PF00443;PF08969;,1.00E-23,CHOYP_LOC100367006.2.2,,,,,,,UBP8_MOUSE,Mus musculus (Mouse),endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; ubiquitin-dependent protein catabolic process [GO:0006511] comp67328_c0_seq1,412,41.9903,0.84562333,14,14,,2.00E-24,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,6.00E-21,CHOYP_BRAFLDRAFT_208436.13.32,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp67339_c0_seq1,403,40.6948,0.60083654,3,5,,2.00E-28,Q13572,"Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)","Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)",GO:0005524; GO:0007596; GO:0005829; GO:0043647; GO:0047325; GO:0032957; GO:0052825; GO:0052831; GO:0052830; GO:0052726; GO:0052725; GO:0052835; GO:0016853; GO:0000287; GO:0007165,"ATP binding; blood coagulation; cytosol; inositol phosphate metabolic process; inositol tetrakisphosphate 1-kinase activity; inositol trisphosphate metabolic process; inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity; inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity; inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity; inositol-1,3,4-trisphosphate 5-kinase activity; inositol-1,3,4-trisphosphate 6-kinase activity; inositol-3,4,6-trisphosphate 1-kinase activity; isomerase activity; magnesium ion binding; signal transduction",PF05770;,,,,,,,,,ITPK1_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate metabolic process [GO:0032957]; neural tube development [GO:0021915]; signal transduction [GO:0007165] comp67339_c0_seq2,365,39.1781,0.64462323,0,9,,,,,,,,,7.00E-13,CHOYP_ITPK1.1.1,,,,,,,,, comp67348_c1_seq1,287,45.6446,0.50603024,6,5,,3.00E-32,Q8NAG6,Ankyrin repeat and LEM domain-containing protein 1 (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3),Ankyrin repeat and LEM domain-containing protein 1 (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3),,,PF12796;PF03020;,3.00E-23,CHOYP_ISCW_ISCW011180.1.1,,,,,,,ANKL1_HUMAN,Homo sapiens (Human), comp67354_c0_seq1,341,43.1085,0.85632478,9,17,,5.00E-25,Q63767,Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas),Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas),GO:0050853; GO:0007186; GO:0007015; GO:0007155; GO:0016477; GO:0005737; GO:0007173; GO:0005925; GO:0008286; GO:0007229; GO:0048011; GO:0005886; GO:0048008; GO:0030335; GO:0001726,B cell receptor signaling pathway; G-protein coupled receptor signaling pathway; actin filament organization; cell adhesion; cell migration; cytoplasm; epidermal growth factor receptor signaling pathway; focal adhesion; insulin receptor signaling pathway; integrin-mediated signaling pathway; neurotrophin TRK receptor signaling pathway; plasma membrane; platelet-derived growth factor receptor signaling pathway; positive regulation of cell migration; ruffle,PF12026;PF08824;PF00018;,,,,,,,,,BCAR1_RAT,Rattus norvegicus (Rat),actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; epidermal growth factor receptor signaling pathway [GO:0007173]; G-protein coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335] comp67354_c0_seq2,241,49.3776,0.77160749,0,0,,3.00E-26,P56945,Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas),Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas),GO:0050853; GO:0007186; GO:0050852; GO:0007015; GO:0007155; GO:0060326; GO:0051301; GO:0008283; GO:0035729; GO:0005829; GO:0007173; GO:0005925; GO:0048012; GO:0008286; GO:0007229; GO:0030027; GO:0048011; GO:0030168; GO:0048008; GO:0010595; GO:0042981; GO:0001558; GO:0001726; GO:0004871; GO:0048010,B cell receptor signaling pathway; G-protein coupled receptor signaling pathway; T cell receptor signaling pathway; actin filament organization; cell adhesion; cell chemotaxis; cell division; cell proliferation; cellular response to hepatocyte growth factor stimulus; cytosol; epidermal growth factor receptor signaling pathway; focal adhesion; hepatocyte growth factor receptor signaling pathway; insulin receptor signaling pathway; integrin-mediated signaling pathway; lamellipodium; neurotrophin TRK receptor signaling pathway; platelet activation; platelet-derived growth factor receptor signaling pathway; positive regulation of endothelial cell migration; regulation of apoptotic process; regulation of cell growth; ruffle; signal transducer activity; vascular endothelial growth factor receptor signaling pathway,PF12026;PF08824;PF00018;,9.00E-22,CHOYP_LOC100374152.1.1,,,,,,,BCAR1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell division [GO:0051301]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; epidermal growth factor receptor signaling pathway [GO:0007173]; G-protein coupled receptor signaling pathway [GO:0007186]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell migration [GO:0010595]; regulation of apoptotic process [GO:0042981]; regulation of cell growth [GO:0001558]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp67355_c0_seq1,361,43.2133,0.30471614,2,23,,2.00E-22,P27088,DNA repair protein complementing XP-A cells homolog (Xeroderma pigmentosum group A-complementing protein homolog),DNA repair protein complementing XP-A cells homolog (Xeroderma pigmentosum group A-complementing protein homolog),GO:0003684; GO:0046872; GO:0000166; GO:0006289; GO:0005634,damaged DNA binding; metal ion binding; nucleotide binding; nucleotide-excision repair; nucleus,PF05181;PF01286;,,,,,,,,,XPA_XENLA,Xenopus laevis (African clawed frog),nucleotide-excision repair [GO:0006289] comp67356_c0_seq1,578,39.1003,0.68037806,9,18,,1.00E-11,Q13489,Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (IAP-1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1),Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1),GO:0038061; GO:0035666; GO:0006915; GO:0007166; GO:0005829; GO:0045087; GO:0070266; GO:0043066; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0043123; GO:0039535; GO:2000116; GO:0050727; GO:0060544; GO:0070424; GO:0034121; GO:0034138; GO:0034142; GO:0004842; GO:0008270,NIK/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; apoptotic process; cell surface receptor signaling pathway; cytosol; innate immune response; necroptosis; negative regulation of apoptotic process; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of RIG-I signaling pathway; regulation of cysteine-type endopeptidase activity; regulation of inflammatory response; regulation of necroptosis; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,BIRC3_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; protein heterooligomerization [GO:0051291]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; spermatogenesis [GO:0007283]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp67419_c0_seq1,281,45.5516,0.77628611,11,19,,2.00E-06,A1BQQ5,Cysteine-rich venom protein Mr30 (CRVP) (Cysteine-rich secretory protein Mr30) (GlaCrisp isoform 1/2/3) (Mr30-1/2),Cysteine-rich venom protein Mr30 (CRVP) (Cysteine-rich secretory protein Mr30) (GlaCrisp isoform 1/2/3) (Mr30-1/2),GO:0005576,extracellular region,PF00188;,,,,,,,,,MR30_CONMR,Conus marmoreus (Marble cone), comp67421_c0_seq1,391,41.9437,0.46981581,5,20,,4.00E-34,Q9CYK2,Glutaminyl-peptide cyclotransferase (EC 2.3.2.5) (Glutaminyl cyclase) (QC) (Glutaminyl-tRNA cyclotransferase),Glutaminyl-peptide cyclotransferase (EC 2.3.2.5) (Glutaminyl cyclase) (QC) (Glutaminyl-tRNA cyclotransferase),GO:0005576; GO:0016603; GO:0008233; GO:0017186; GO:0006508; GO:0008270,"extracellular region; glutaminyl-peptide cyclotransferase activity; peptidase activity; peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; proteolysis; zinc ion binding",PF04389;,,,,,,,,,QPCT_MOUSE,Mus musculus (Mouse),"peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase [GO:0017186]" comp67496_c0_seq1,349,40.6877,1.04229563,19,4,,1.00E-07,A2AJA9,Uncharacterized protein C9orf172 homolog,Uncharacterized protein C9orf172 homolog,,,,,,,,,,,,CI172_MOUSE,Mus musculus (Mouse), comp67517_c0_seq1,232,50.431,0.52955529,2,14,,3.00E-13,P21139,Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1),Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1),GO:0004559; GO:0030246; GO:0005783; GO:0006013; GO:0008270,alpha-mannosidase activity; carbohydrate binding; endoplasmic reticulum; mannose metabolic process; zinc ion binding,PF09261;PF01074;PF07748;,,,,,,,,,MA2C1_RAT,Rattus norvegicus (Rat),mannose metabolic process [GO:0006013]; protein deglycosylation [GO:0006517] comp67521_c1_seq1,230,39.5652,1.00436681,1,20,,2.00E-11,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp67531_c0_seq1,202,28.7129,0.73198909,3,24,,1.00E-10,P47043,Zinc-responsive transcriptional regulator ZAP1,Zinc-responsive transcriptional regulator ZAP1,GO:0000977; GO:0005634; GO:0045944; GO:0034225; GO:0000981; GO:0008270,RNA polymerase II regulatory region sequence-specific DNA binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; sequence-specific DNA binding RNA polymerase II transcription factor activity; zinc ion binding,PF00096;PF13912;,,,,,,,,,ZAP1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0034225]; transcription, DNA-templated [GO:0006351]" comp67550_c0_seq1,203,36.9458,0.62964491,0,13,,3.00E-10,P31843,RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog),RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog),GO:0003723; GO:0006278; GO:0003964; GO:0003968; GO:0005739,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; RNA-directed RNA polymerase activity; mitochondrion,PF00078;,1.00E-12,CHOYP_LOC580404.3.3,,,,,,,RRPO_OENBE,Oenothera berteroana (Bertero's evening primrose), comp67572_c0_seq2,1054,44.4972,0.73146322,29,27,,1.00E-80,Q9JM13,Rab5 GDP/GTP exchange factor (Rabex-5),Rab5 GDP/GTP exchange factor (Rabex-5),GO:0003677; GO:0005769; GO:0006897; GO:1900235; GO:0046580; GO:0050728; GO:1900165; GO:0002686; GO:0043305; GO:0001933; GO:0048261; GO:0015031; GO:0055037; GO:0060368; GO:0004842; GO:0031982; GO:0008270,DNA binding; early endosome; endocytosis; negative regulation of Kit signaling pathway; negative regulation of Ras protein signal transduction; negative regulation of inflammatory response; negative regulation of interleukin-6 secretion; negative regulation of leukocyte migration; negative regulation of mast cell degranulation; negative regulation of protein phosphorylation; negative regulation of receptor-mediated endocytosis; protein transport; recycling endosome; regulation of Fc receptor mediated stimulatory signaling pathway; ubiquitin-protein ligase activity; vesicle; zinc ion binding,PF02204;PF01754;,3.00E-73,CHOYP_RABX5.2.2,,,,,,,RABX5_MOUSE,Mus musculus (Mouse),endocytosis [GO:0006897]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein targeting to membrane [GO:0006612]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] comp67585_c0_seq1,239,60.6695,1.2328983,0,32,,4.00E-46,Q6A8J7,Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS),Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS),GO:0005524; GO:0005737; GO:0004821; GO:0006427,ATP binding; cytoplasm; histidine-tRNA ligase activity; histidyl-tRNA aminoacylation,PF03129;,,,,,,,,,SYH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),histidyl-tRNA aminoacylation [GO:0006427] comp67594_c0_seq1,270,61.4815,0.9444134,4,10,,5.00E-17,Q9UT61,Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase),Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase),GO:0004559; GO:0030246; GO:0005829; GO:0000329; GO:0006013; GO:0009313; GO:0008270,alpha-mannosidase activity; carbohydrate binding; cytosol; fungal-type vacuole membrane; mannose metabolic process; oligosaccharide catabolic process; zinc ion binding,PF09261;PF01074;PF07748;,,,,,,,,,MAN1_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517] comp67611_c0_seq1,207,35.7488,0.76472373,1,12,,3.00E-06,Q8BW94,"Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3)","Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3)",GO:0005524; GO:0035085; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; cilium axoneme; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF12780;PF08393;PF03028;PF12777;,,,,,,,,,DYH3_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp67614_c0_seq1,543,39.0424,0.96970026,9,29,,9.00E-17,P51522,Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1),Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZNF83_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp6764_c0_seq1,283,43.8163,0.22450873,6,0,,1.00E-20,P82450,Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit],Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit],GO:0004091; GO:0005764; GO:0001681,carboxylesterase activity; lysosome; sialate O-acetylesterase activity,PF03629;,,,,,,,,,SIAE_RAT,Rattus norvegicus (Rat), comp67655_c0_seq1,394,43.1472,0.82567422,32,0,,2.00E-14,P83553,Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP),Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP),GO:0007155; GO:0005578,cell adhesion; proteinaceous extracellular matrix,,,,,,,,,,DERM_BIOGL,Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail),cell adhesion [GO:0007155] comp67667_c0_seq1,380,46.0526,0.50800352,12,12,,2.00E-23,Q6PDJ1,VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1),VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1),GO:0006816; GO:0016021,calcium ion transport; integral to membrane,PF00092;PF08399;,8.00E-25,CHOYP_CAHD1.4.6,,,,,,,CAHD1_MOUSE,Mus musculus (Mouse),calcium ion transport [GO:0006816] comp67675_c0_seq1,279,51.2545,0.60918504,1,31,,3.00E-39,Q9Z2J0,Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3),Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3),GO:0008520; GO:0016324; GO:0009925; GO:0007420; GO:0005903; GO:0005737; GO:0033300; GO:0016021; GO:0043229; GO:0030324; GO:0009636; GO:0070890; GO:0070904,L-ascorbate:sodium symporter activity; apical plasma membrane; basal plasma membrane; brain development; brush border; cytoplasm; dehydroascorbic acid transporter activity; integral to membrane; intracellular organelle; lung development; response to toxic substance; sodium-dependent L-ascorbate transmembrane transporter activity; transepithelial L-ascorbic acid transport,PF00860;,1.00E-53,CHOYP_BRAFLDRAFT_90196.1.2,2.00E-34,ruditapes_c20247,,,,,S23A1_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; lung development [GO:0030324]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904] comp67678_c0_seq1,255,61.5686,0.92027559,1,15,,3.00E-51,Q6AAT0,Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS),Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS),GO:0005524; GO:0004817; GO:0006423; GO:0005737; GO:0008270,ATP binding; cysteine-tRNA ligase activity; cysteinyl-tRNA aminoacylation; cytoplasm; zinc ion binding,PF09190;PF01406;,,,,,,,,,SYC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cysteinyl-tRNA aminoacylation [GO:0006423] comp67689_c0_seq1,242,46.6942,0.4570611,9,6,,1.00E-10,Q2KIP2,Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein),Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein),GO:0005524; GO:0005813; GO:0005694; GO:0005737; GO:2000751; GO:0072354; GO:0007064; GO:0005634; GO:0071459; GO:0090231; GO:0005819,"ATP binding; centrosome; chromosome; cytoplasm; histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; histone kinase activity (H3-T3 specific); mitotic sister chromatid cohesion; nucleus; protein localization to chromosome, centromeric region; regulation of spindle checkpoint; spindle",PF12330;,2.00E-18,CHOYP_LOC579644.1.1,4.00E-31,ruditapes_c13526,,,,,HASP_BOVIN,Bos taurus (Bovine),"histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore [GO:2000751]; intracellular signal transduction [GO:0035556]; mitotic sister chromatid cohesion [GO:0007064]; protein localization to chromosome, centromeric region [GO:0071459]; regulation of spindle checkpoint [GO:0090231]" comp67690_c0_seq1,659,44.9165,0.4835176,29,20,,2.00E-08,G3V893,Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1),Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1),GO:0007420; GO:0080182; GO:0035097; GO:0046872; GO:0048812; GO:0005634; GO:2000327; GO:0050671; GO:0002052; GO:0040029; GO:0006355; GO:0044212; GO:0006351,"brain development; histone H3-K4 trimethylation; histone methyltransferase complex; metal ion binding; neuron projection morphogenesis; nucleus; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; positive regulation of lymphocyte proliferation; positive regulation of neuroblast proliferation; regulation of gene expression, epigenetic; regulation of transcription, DNA-dependent; transcription regulatory region DNA binding; transcription, DNA-dependent",PF13912;,,,,,,,,,ZN335_RAT,Rattus norvegicus (Rat),"brain development [GO:0007420]; histone H3-K4 trimethylation [GO:0080182]; neuron projection morphogenesis [GO:0048812]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of neuroblast proliferation [GO:0002052]; regulation of gene expression, epigenetic [GO:0040029]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp67698_c0_seq1,216,49.537,0.1517515,0,9,,3.00E-12,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp67706_c0_seq1,472,41.7373,0.39002443,19,0,,2.00E-18,Q91V01,Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5),Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5),GO:0047184; GO:0005789; GO:0016021; GO:0008654; GO:0097006,1-acylglycerophosphocholine O-acyltransferase activity; endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process; regulation of plasma lipoprotein particle levels,PF03062;,,,,,,,,,MBOA5_MOUSE,Mus musculus (Mouse),phospholipid biosynthetic process [GO:0008654]; regulation of plasma lipoprotein particle levels [GO:0097006] comp67713_c1_seq1,271,42.4354,0.41137886,3,0,,4.00E-34,Q7ZX75,Protein LMBR1L,Protein LMBR1L,GO:0006897; GO:0016021; GO:0005886,endocytosis; integral to membrane; plasma membrane,PF04791;,1.00E-27,CHOYP_LOC100376583.1.1,,,,,,,LMBRL_XENLA,Xenopus laevis (African clawed frog),endocytosis [GO:0006897] comp67740_c0_seq1,231,42.4242,1.08505435,4,0,,3.00E-13,P36423,Thromboxane-A synthase (TS) (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1),Thromboxane-A synthase (TS) (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1),GO:0030644; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0004497; GO:0016705; GO:0045907; GO:0001516; GO:0004796,"cellular chloride ion homeostasis; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; positive regulation of vasoconstriction; prostaglandin biosynthetic process; thromboxane-A synthase activity",PF00067;,,,,,,,,,THAS_MOUSE,Mus musculus (Mouse),cellular chloride ion homeostasis [GO:0030644]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516] comp67755_c0_seq1,261,58.6207,1.14512171,2,14,,3.00E-49,Q6A5D0,Uronate isomerase (EC 5.3.1.12) (Glucuronate isomerase) (Uronic isomerase),Uronate isomerase (EC 5.3.1.12) (Glucuronate isomerase) (Uronic isomerase),GO:0006064; GO:0008880,glucuronate catabolic process; glucuronate isomerase activity,PF02614;,,,,,,,,,UXAC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glucuronate catabolic process [GO:0006064] comp67757_c0_seq2,902,47.0067,0.32149572,34,22,,6.00E-107,Q5RIW8,Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23),Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11573;,4.00E-110,CHOYP_MED23.1.1,,,,,,,MED23_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cardiovascular system development [GO:0072358]; negative regulation of neurogenesis [GO:0050768]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp67761_c0_seq1,408,46.5686,0.40900246,8,24,,7.00E-21,Q9D565,WD repeat-containing protein 64,WD repeat-containing protein 64,,,PF00400;,1.00E-30,CHOYP_LOC582771.1.1,,,,,,,WDR64_MOUSE,Mus musculus (Mouse), comp67778_c0_seq1,348,58.908,1.23973758,0,22,,6.00E-19,Q6GEP3,Zinc-type alcohol dehydrogenase-like protein SAR2277,Zinc-type alcohol dehydrogenase-like protein SAR2277,GO:0016491; GO:0008270,oxidoreductase activity; zinc ion binding,PF08240;PF00107;,,,,,,,,,ZDH1_STAAR,Staphylococcus aureus (strain MRSA252), comp67789_c0_seq1,350,69.1429,0.83960499,0,12,,2.00E-60,A1W857,Serine/threonine transporter SstT (Na(+)/serine-threonine symporter),Serine/threonine transporter SstT (Na(+)/serine-threonine symporter),GO:0003333; GO:0016021; GO:0005886; GO:0022889; GO:0017153; GO:0015565,amino acid transmembrane transport; integral to membrane; plasma membrane; serine transmembrane transporter activity; sodium:dicarboxylate symporter activity; threonine efflux transmembrane transporter activity,PF00375;,,,,,,,,,SSTT_ACISJ,Acidovorax sp. (strain JS42),serine transport [GO:0032329]; threonine transport [GO:0015826] comp67815_c0_seq1,723,43.0152,0.36770004,22,36,,7.00E-48,F1N9Y5,Tyrosine-protein kinase SYK (EC 2.7.10.2),Tyrosine-protein kinase SYK (EC 2.7.10.2),GO:0005524; GO:0019815; GO:0050853; GO:0042101; GO:0007257; GO:0002250; GO:0043366; GO:0048514; GO:0071226; GO:0005829; GO:0042742; GO:0032009; GO:0007167; GO:0045087; GO:0007229; GO:0007159; GO:0019370; GO:0001945; GO:0002281; GO:0002283; GO:0030593; GO:0004715; GO:0045579; GO:0046638; GO:0046641; GO:0045780; GO:0050850; GO:0033630; GO:0050715; GO:0045588; GO:0045425; GO:0045401; GO:0043306; GO:0050731; GO:0046777; GO:0004716; GO:0070372; GO:0090237; GO:0043313; GO:0050764; GO:0090330; GO:0032928; GO:0002554,ATP binding; B cell receptor complex; B cell receptor signaling pathway; T cell receptor complex; activation of JUN kinase activity; adaptive immune response; beta selection; blood vessel morphogenesis; cellular response to molecule of fungal origin; cytosol; defense response to bacterium; early phagosome; enzyme linked receptor protein signaling pathway; innate immune response; integrin-mediated signaling pathway; leukocyte cell-cell adhesion; leukotriene biosynthetic process; lymph vessel development; macrophage activation involved in immune response; neutrophil activation involved in immune response; neutrophil chemotaxis; non-membrane spanning protein tyrosine kinase activity; positive regulation of B cell differentiation; positive regulation of alpha-beta T cell differentiation; positive regulation of alpha-beta T cell proliferation; positive regulation of bone resorption; positive regulation of calcium-mediated signaling; positive regulation of cell adhesion mediated by integrin; positive regulation of cytokine secretion; positive regulation of gamma-delta T cell differentiation; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of interleukin-3 biosynthetic process; positive regulation of mast cell degranulation; positive regulation of peptidyl-tyrosine phosphorylation; protein autophosphorylation; receptor signaling protein tyrosine kinase activity; regulation of ERK1 and ERK2 cascade; regulation of arachidonic acid secretion; regulation of neutrophil degranulation; regulation of phagocytosis; regulation of platelet aggregation; regulation of superoxide anion generation; serotonin secretion by platelet,PF07714;PF00017;,1.00E-20,CHOYP_LOC589201.1.1,,,,,,,KSYK_CHICK,Gallus gallus (Chicken),adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cellular response to molecule of fungal origin [GO:0071226]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of mast cell degranulation [GO:0043306]; protein phosphorylation [GO:0006468]; regulation of arachidonic acid secretion [GO:0090237]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; serotonin secretion by platelet [GO:0002554]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp67818_c0_seq1,481,44.2827,0.68115468,3,19,,4.00E-60,Q8K2V6,Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11),Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11),GO:0005737; GO:0005634; GO:0008565; GO:0006610,cytoplasm; nucleus; protein transporter activity; ribosomal protein import into nucleus,PF03810;,8.00E-39,CHOYP_IPO11.1.1,,,,,,,IPO11_MOUSE,Mus musculus (Mouse),ribosomal protein import into nucleus [GO:0006610]; transcription factor import into nucleus [GO:0042991] comp67849_c0_seq1,241,40.6639,0.30698203,2,27,,7.00E-09,B0BNX3,Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C),Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C),GO:0006777,Mo-molybdopterin cofactor biosynthetic process,PF01967;,2.00E-11,CHOYP_MTR_5G015740.1.1,,,,,,,MOAC_ACTPJ,Actinobacillus pleuropneumoniae serotype 3 (strain JL03),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp67862_c1_seq1,333,42.3423,0.0701687,1,17,,7.00E-36,Q14376,UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase),UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase),GO:0003978; GO:0044237; GO:0050662; GO:0005829; GO:0019388; GO:0044281,UDP-glucose 4-epimerase activity; cellular metabolic process; coenzyme binding; cytosol; galactose catabolic process; small molecule metabolic process,PF16363;,4.00E-16,CHOYP_LOC100370520.1.1,,,,,,,GALE_HUMAN,Homo sapiens (Human),galactose catabolic process [GO:0019388] comp67866_c0_seq1,225,40.4444,0.88629202,6,5,,2.00E-10,Q6AZB8,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,2.00E-17,CHOYP_LOC100537368.2.2,,,,,,,HARB1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp67868_c0_seq1,216,34.7222,0.61736743,1,11,,,,,,,,,2.00E-11,CHOYP_contig_022990,,,,,,,,, comp67910_c0_seq1,402,44.0299,0.92762722,0,34,,3.00E-21,O35899,Sodium-dependent serotonin transporter (5HT transporter) (5HTT) (Solute carrier family 6 member 4),Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4),GO:0051015; GO:0012505; GO:0010008; GO:0005887; GO:0005886; GO:0051259; GO:0051610; GO:0005335,actin filament binding; endomembrane system; endosome membrane; integral to plasma membrane; plasma membrane; protein oligomerization; serotonin uptake; serotonin:sodium symporter activity,PF03491;PF00209;,,,,,,,,,SC6A4_CAVPO,Cavia porcellus (Guinea pig),protein oligomerization [GO:0051259]; serotonin uptake [GO:0051610] comp67911_c0_seq1,216,34.7222,0.30912343,0,9,,6.00E-07,P21328,RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF14529;PF00078;,,,,,,,,,RTJK_DROME,Drosophila melanogaster (Fruit fly), comp67956_c0_seq2,305,50.1639,0.53292109,8,0,,2.00E-43,P80457,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0009055; GO:0005576; GO:0050660; GO:0005506; GO:0043546; GO:0005777; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; extracellular region; flavin adenine dinucleotide binding; iron ion binding; molybdopterin cofactor binding; peroxisome; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,2.00E-31,CHOYP_XDH.2.3,,,,,,,XDH_BOVIN,Bos taurus (Bovine),xanthine catabolic process [GO:0009115] comp67960_c0_seq1,271,42.4354,1.06858598,8,24,,3.00E-27,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,,,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp67963_c0_seq1,321,47.352,0.89336744,0,11,,2.00E-33,P15396,Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],GO:0035529; GO:0005576; GO:0006955; GO:0016021; GO:0046872; GO:0003676; GO:0004528; GO:0030247; GO:0005044,NADH pyrophosphatase activity; extracellular region; immune response; integral to membrane; metal ion binding; nucleic acid binding; phosphodiesterase I activity; polysaccharide binding; scavenger receptor activity,PF01223;PF01663;PF01033;,,,,,,,,,ENPP3_BOVIN,Bos taurus (Bovine),immune response [GO:0006955] comp67974_c0_seq1,269,36.803,0.44190463,8,0,,4.00E-08,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp68009_c0_seq1,440,47.5,0.61938522,10,15,,3.00E-50,A7MB45,"Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1)","Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1)",GO:0005524; GO:0003987; GO:0005739,ATP binding; acetate-CoA ligase activity; mitochondrion,PF16177;PF00501;PF13193;,5.00E-54,CHOYP_ACSS3.1.1,,,,,,,ACSS3_BOVIN,Bos taurus (Bovine),metabolic process [GO:0008152] comp6800_c0_seq1,356,33.7079,0.69591192,5,2,,3.00E-08,Q5XXR3,Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6),Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6),GO:0005089; GO:0035556; GO:0030027; GO:0030032; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; intracellular signal transduction; lamellipodium; lamellipodium assembly; phospholipid binding; regulation of Rho protein signal transduction,PF16523;PF00307;PF00169;PF00621;PF14604;,,,,,,,,,ARHG6_RAT,Rattus norvegicus (Rat),intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; regulation of Rho protein signal transduction [GO:0035023] comp68022_c0_seq1,217,39.6313,0.53695722,3,24,,4.00E-15,Q5PQS7,Coiled-coil domain-containing protein 174,Coiled-coil domain-containing protein 174,,,PF13300;,,,,,,,,,CC019_RAT,Rattus norvegicus (Rat), comp68049_c0_seq1,229,52.4017,0.4126873,2,17,,7.00E-09,Q47690,Homocysteine S-methyltransferase (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase),Homocysteine S-methyltransferase (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase),GO:0008898; GO:0046872; GO:0009086; GO:0006974,homocysteine S-methyltransferase activity; metal ion binding; methionine biosynthetic process; response to DNA damage stimulus,PF02574;,,,,,,,,,MMUM_ECOLI,Escherichia coli (strain K12),cellular response to DNA damage stimulus [GO:0006974]; methionine biosynthetic process [GO:0009086]; S-methylmethionine metabolic process [GO:0033477] comp68077_c0_seq1,255,47.8431,0.28829272,6,0,,8.00E-23,Q9WVR3,"Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)","Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)",GO:0005794; GO:0007015; GO:0007420; GO:0007155; GO:0005856; GO:0005829; GO:0001958; GO:0006897; GO:0030175; GO:0006006; GO:0032957; GO:0004445; GO:0030027; GO:0008156; GO:0043407; GO:0008285; GO:0010629; GO:0046627; GO:0043569; GO:0010977; GO:0010642; GO:0006661; GO:0046856; GO:0005547; GO:0005886; GO:0009791; GO:0042493; GO:0032868; GO:0097178,"Golgi apparatus; actin filament organization; brain development; cell adhesion; cytoskeleton; cytosol; endochondral ossification; endocytosis; filopodium; glucose metabolic process; inositol trisphosphate metabolic process; inositol-polyphosphate 5-phosphatase activity; lamellipodium; negative regulation of DNA replication; negative regulation of MAP kinase activity; negative regulation of cell proliferation; negative regulation of gene expression; negative regulation of insulin receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of neuron projection development; negative regulation of platelet-derived growth factor receptor signaling pathway; phosphatidylinositol biosynthetic process; phosphatidylinositol dephosphorylation; phosphatidylinositol-3,4,5-trisphosphate binding; plasma membrane; post-embryonic development; response to drug; response to insulin stimulus; ruffle assembly",PF03372;PF00536;PF00017;,1.00E-20,CHOYP_SHIP2.1.1,,,,,,,SHIP2_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; cell adhesion [GO:0007155]; endochondral ossification [GO:0001958]; immune system process [GO:0002376]; inositol trisphosphate metabolic process [GO:0032957]; negative regulation of DNA replication [GO:0008156]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; phosphatidylinositol dephosphorylation [GO:0046856]; response to drug [GO:0042493] comp68087_c0_seq1,428,39.0187,0.49367358,17,32,,8.00E-12,Q86UZ6,Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340),Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340),GO:0046872; GO:2001199; GO:0030853; GO:0045650; GO:0045656; GO:0003676; GO:0005634; GO:2001200; GO:0006355; GO:0006351,"metal ion binding; negative regulation of dendritic cell differentiation; negative regulation of granulocyte differentiation; negative regulation of macrophage differentiation; negative regulation of monocyte differentiation; nucleic acid binding; nucleus; positive regulation of dendritic cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;,,,,,,,,,ZBT46_HUMAN,Homo sapiens (Human),"negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp68097_c0_seq1,330,47.8788,0.59107686,6,24,,9.00E-32,Q8VHQ2,Suppressor of cytokine signaling 7 (SOCS-7),Suppressor of cytokine signaling 7 (SOCS-7),GO:0005737; GO:0045444; GO:0008286; GO:0035556; GO:0009968; GO:0005634; GO:0005886; GO:0016567; GO:0040008,cytoplasm; fat cell differentiation; insulin receptor signaling pathway; intracellular signal transduction; negative regulation of signal transduction; nucleus; plasma membrane; protein ubiquitination; regulation of growth,PF00017;PF07525;,2.00E-39,CHOYP_LOC588073.1.1,,,,,,,SOCS7_MOUSE,Mus musculus (Mouse),cerebral cortex radially oriented cell migration [GO:0021799]; cytokine-mediated signaling pathway [GO:0019221]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; layer formation in cerebral cortex [GO:0021819]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; protein ubiquitination [GO:0016567]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of growth [GO:0040008] comp68114_c0_seq1,238,42.437,1.25385587,2,16,,2.00E-09,Q5RJI4,"Protein kinase domain-containing protein, cytoplasmic (EC 2.7.-.-) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)","Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)",GO:0005524; GO:0005794; GO:0030282; GO:0030154; GO:0048566; GO:0048286; GO:0035264; GO:0042997; GO:0060021; GO:0030501; GO:0032332; GO:0004672; GO:0015031; GO:0001501,ATP binding; Golgi apparatus; bone mineralization; cell differentiation; embryonic digestive tract development; lung alveolus development; multicellular organism growth; negative regulation of Golgi to plasma membrane protein transport; palate development; positive regulation of bone mineralization; positive regulation of chondrocyte differentiation; protein kinase activity; protein transport; skeletal system development,PF12260;,,,,,,,,,PKDCC_MOUSE,Mus musculus (Mouse),bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; palate development [GO:0060021]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; skeletal system development [GO:0001501] comp68125_c0_seq1,299,64.5485,1.25916174,3,15,,1.00E-07,Q66HG3,Beta-Ala-His dipeptidase (EC 3.4.13.20) (CNDP dipeptidase 1) (Carnosine dipeptidase 1),Beta-Ala-His dipeptidase (EC 3.4.13.20) (CNDP dipeptidase 1) (Carnosine dipeptidase 1),GO:0004180; GO:0016805; GO:0046872; GO:0008237; GO:0006508; GO:0034701,carboxypeptidase activity; dipeptidase activity; metal ion binding; metallopeptidase activity; proteolysis; tripeptidase activity,PF07687;PF01546;,,,,,,,,,CNDP1_RAT,Rattus norvegicus (Rat),peptide catabolic process [GO:0043171] comp68130_c0_seq1,202,34.6535,0.50373443,0,12,,4.00E-06,P03010,Putative AC9 transposase,Putative AC9 transposase,GO:0003677; GO:0006310; GO:0032196,DNA binding; DNA recombination; transposition,PF05699;PF14372;,,,,,,,,,TRAC9_MAIZE,Zea mays (Maize),DNA recombination [GO:0006310]; transposition [GO:0032196] comp68135_c0_seq1,510,44.5098,0.75615556,14,16,,1.00E-61,E9Q4S1,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)","High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)",GO:0004114; GO:0006198; GO:0035556; GO:0046872; GO:0000156; GO:0006355,"3',5'-cyclic-nucleotide phosphodiesterase activity; cAMP catabolic process; intracellular signal transduction; metal ion binding; phosphorelay response regulator activity; regulation of transcription, DNA-dependent",PF13426;PF08629;PF00233;,,,,,,,,,PDE8B_MOUSE,Mus musculus (Mouse),behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] comp68137_c0_seq1,471,43.949,0.62328144,23,25,,3.00E-73,Q28CH3,UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-),UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-),GO:0016779,nucleotidyltransferase activity,PF01704;,4.00E-42,CHOYP_BRAFLDRAFT_125327.1.1,,,,,,,UAP1L_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp68148_c0_seq1,288,42.3611,0.23401092,0,5,,,,,,,,,2.00E-19,CHOYP_LOC100862954.1.1,,,,,,,,, comp68150_c0_seq1,349,43.8395,0.41952399,9,11,,3.00E-21,O15040,Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297),Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297),GO:0006914; GO:0008219,autophagy; cell death,PF06462;,3.00E-18,CHOYP_BRAFLDRAFT_216841.3.4,,,,,,,TCPR2_HUMAN,Homo sapiens (Human),autophagy [GO:0006914] comp68169_c0_seq1,223,45.7399,1.12131635,5,23,,4.00E-32,Q03206,Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1),Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1),GO:0005525; GO:0003924; GO:0006915; GO:0048846; GO:0031103; GO:0010171; GO:0009986; GO:0031410; GO:0005829; GO:0033563; GO:0043652; GO:0016021; GO:0009898; GO:0008045; GO:0002119; GO:0001764; GO:0030334; GO:0050764; GO:0007264,GTP binding; GTPase activity; apoptotic process; axon extension involved in axon guidance; axon regeneration; body morphogenesis; cell surface; cytoplasmic vesicle; cytosol; dorsal/ventral axon guidance; engulfment of apoptotic cell; integral to membrane; internal side of plasma membrane; motor neuron axon guidance; nematode larval development; neuron migration; regulation of cell migration; regulation of phagocytosis; small GTPase mediated signal transduction,PF00071;,,,3.00E-13,ruditapes2_c2197,,,,,RAC1_CAEEL,Caenorhabditis elegans,"apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; engulfment of apoptotic cell [GO:0043652]; gastrulation [GO:0007369]; motor neuron axon guidance [GO:0008045]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264]" comp68169_c1_seq1,342,43.5673,0.74728308,5,21,,1.00E-30,Q9TU25,Ras-related C3 botulinum toxin substrate 2 (p21-Rac2),Ras-related C3 botulinum toxin substrate 2 (p21-Rac2),GO:0005525; GO:0003924; GO:0030036; GO:0030031; GO:0006935; GO:0005737; GO:0016020; GO:0005635; GO:0008284; GO:0060263; GO:0007264,GTP binding; GTPase activity; actin cytoskeleton organization; cell projection assembly; chemotaxis; cytoplasm; membrane; nuclear envelope; positive regulation of cell proliferation; regulation of respiratory burst; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAC2_BOVIN,Bos taurus (Bovine),actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; G-protein coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of cell-substrate adhesion [GO:0010810]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of respiratory burst [GO:0060263]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264] comp68172_c0_seq1,240,45.8333,0.74155134,2,3,,4.00E-23,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp68188_c1_seq1,551,43.3757,0.66157521,39,11,,,,,,,,,4.00E-37,CHOYP_BRAFLDRAFT_119590.3.3,,,,,,,,, comp68191_c0_seq1,228,37.2807,1.03856873,4,27,,3.00E-15,Q9JME2,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),GO:0000139; GO:0001537; GO:0050659; GO:0016051; GO:0002063; GO:0047756; GO:0030206; GO:0048589; GO:0042733; GO:0048703; GO:0016021; GO:0043066; GO:0030512; GO:0033037; GO:0036342; GO:0009791; GO:0042127; GO:0007585,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; carbohydrate biosynthetic process; chondrocyte development; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; developmental growth; embryonic digit morphogenesis; embryonic viscerocranium morphogenesis; integral to membrane; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; polysaccharide localization; post-anal tail morphogenesis; post-embryonic development; regulation of cell proliferation; respiratory gaseous exchange,PF03567;,,,,,,,,,CHSTB_MOUSE,Mus musculus (Mouse),carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585] comp68222_c0_seq1,204,63.7255,0.92191564,0,0,,6.00E-07,P52667,HTH-type transcriptional regulator EstR (Esterase operon transcriptional regulator),HTH-type transcriptional regulator EstR (Esterase operon transcriptional regulator),GO:0003677; GO:0003700; GO:0006351,"DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00126;PF03466;,,,,,,,,,ESTR_ACIAD,Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1),"transcription, DNA-templated [GO:0006351]" comp68272_c0_seq1,461,40.9978,0.5281232,29,14,,5.00E-47,Q8N960,Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100),GO:0030953; GO:0005813; GO:0021987; GO:0005737; GO:0022027; GO:0022008; GO:0032886; GO:0032880,astral microtubule organization; centrosome; cerebral cortex development; cytoplasm; interkinetic nuclear migration; neurogenesis; regulation of microtubule-based process; regulation of protein localization,PF00168;PF12416;,2.00E-41,CHOYP_CE120.2.2,,,,,,,CE120_HUMAN,Homo sapiens (Human),astral microtubule organization [GO:0030953]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; regulation of protein localization [GO:0032880] comp68277_c1_seq1,649,38.5208,0.81116777,8,88,,3.00E-42,Q3ZCC3,TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6),GO:0035631; GO:0007249; GO:0050852; GO:0042088; GO:0007250; GO:0019886; GO:0045453; GO:0005938; GO:0048468; GO:0005829; GO:0070498; GO:0009898; GO:0005811; GO:0043011; GO:0000122; GO:0001843; GO:0031965; GO:0042475; GO:0001503; GO:0030316; GO:0048471; GO:0043123; GO:0043507; GO:0051092; GO:0002726; GO:0042102; GO:0045084; GO:0032743; GO:0045410; GO:0031666; GO:0045672; GO:0045944; GO:2000679; GO:0070534; GO:0051865; GO:0042981; GO:0051023; GO:0004871; GO:0004842; GO:0008270,CD40 receptor complex; I-kappaB kinase/NF-kappaB cascade; T cell receptor signaling pathway; T-helper 1 type immune response; activation of NF-kappaB-inducing kinase activity; antigen processing and presentation of exogenous peptide antigen via MHC class II; bone resorption; cell cortex; cell development; cytosol; interleukin-1-mediated signaling pathway; internal side of plasma membrane; lipid particle; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nuclear membrane; odontogenesis of dentin-containing tooth; ossification; osteoclast differentiation; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell cytokine production; positive regulation of T cell proliferation; positive regulation of interleukin-12 biosynthetic process; positive regulation of interleukin-2 production; positive regulation of interleukin-6 biosynthetic process; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription regulatory region DNA binding; protein K63-linked ubiquitination; protein autoubiquitination; regulation of apoptotic process; regulation of immunoglobulin secretion; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF02176;,,,4.00E-42,ruditapes_c28561,,,,,TRAF6_BOVIN,Bos taurus (Bovine),activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088] comp68284_c0_seq1,327,60.2446,1.01864307,0,30,,3.00E-30,P43329,ATP-dependent RNA helicase HrpA (EC 3.6.4.13),ATP-dependent RNA helicase HrpA (EC 3.6.4.13),GO:0005524; GO:0004004; GO:0009451; GO:0006397; GO:0003676,ATP binding; ATP-dependent RNA helicase activity; RNA modification; mRNA processing; nucleic acid binding,PF00270;PF11898;PF04408;PF00271;PF07717;,,,,,,,,,HRPA_ECOLI,Escherichia coli (strain K12),mRNA processing [GO:0006397]; RNA modification [GO:0009451] comp68304_c0_seq1,258,46.8992,1.13411665,1,18,,4.00E-15,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp68376_c0_seq1,216,46.7593,0.35028999,7,5,,,,,,,,,7.00E-23,CHOYP_LOC577371.1.2,,,,,,,,, comp68376_c1_seq1,509,46.3654,0.60337411,24,19,,8.00E-55,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-74,CHOYP_DNAH5.2.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp68389_c0_seq1,369,43.9024,0.73357257,10,13,,5.00E-12,P12111,Collagen alpha-3(VI) chain,Collagen alpha-3(VI) chain,GO:0007411; GO:0007155; GO:0030574; GO:0005589; GO:0005788; GO:0022617; GO:0005615; GO:0007517; GO:0042383; GO:0004867,axon guidance; cell adhesion; collagen catabolic process; collagen type VI; endoplasmic reticulum lumen; extracellular matrix disassembly; extracellular space; muscle organ development; sarcolemma; serine-type endopeptidase inhibitor activity,PF01391;PF00014;PF00092;,,,,,,,,,CO6A3_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; muscle organ development [GO:0007517] comp68420_c0_seq1,1114,45.4219,0.59359634,4,31,,4.00E-16,A2RAF3,Dicer-like protein 1 [Includes: Endoribonuclease dcl1 (EC 3.1.26.-); ATP-dependent helicase dcl1 (EC 3.6.4.-)],Dicer-like protein 1 [Includes: Endoribonuclease dcl1 (EC 3.1.26.-); ATP-dependent helicase dcl1 (EC 3.6.4.-)],GO:0005524; GO:0008026; GO:0003723; GO:0006396; GO:0051607; GO:0046872; GO:0050688; GO:0004525,ATP binding; ATP-dependent helicase activity; RNA binding; RNA processing; defense response to virus; metal ion binding; regulation of defense response to virus; ribonuclease III activity,PF03368;PF00271;PF04851;PF00636;,,,,,,,,,DCL1_ASPNC,Aspergillus niger (strain CBS 513.88 / FGSC A1513),defense response to virus [GO:0051607]; regulation of defense response to virus [GO:0050688]; RNA processing [GO:0006396] comp68429_c0_seq1,202,44.5545,0.42648104,0,6,,3.00E-08,P91685,Metabotropic glutamate receptor (DmGluRA),Metabotropic glutamate receptor (DmGluRA),GO:0015485; GO:0016595; GO:0001641; GO:0005887; GO:0045121; GO:0007528; GO:0051966,"cholesterol binding; glutamate binding; group II metabotropic glutamate receptor activity; integral to plasma membrane; membrane raft; neuromuscular junction development; regulation of synaptic transmission, glutamatergic",PF00003;PF01094;PF07562;,,,,,,,,,GRM_DROME,Drosophila melanogaster (Fruit fly),"G-protein coupled glutamate receptor signaling pathway [GO:0007216]; neuromuscular junction development [GO:0007528]; regulation of synaptic transmission, glutamatergic [GO:0051966]; terminal button organization [GO:0072553]" comp68446_c0_seq1,212,38.2075,0.39011857,1,7,,5.00E-17,Q6XPS3,"Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)","Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)",GO:0000139; GO:0005789; GO:0016021; GO:0005216; GO:0035335; GO:0006661; GO:0016314; GO:0004725; GO:0008138; GO:0044281,"Golgi membrane; endoplasmic reticulum membrane; integral to membrane; ion channel activity; peptidyl-tyrosine dephosphorylation; phosphatidylinositol biosynthetic process; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; small molecule metabolic process",PF00782;PF10409;,2.00E-11,CHOYP_LOC752773.1.2,,,,,,,TPTE2_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661] comp6844_c0_seq1,234,64.1026,1.31405719,0,8,,8.00E-19,A4QDF8,Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A),Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A),GO:0051539; GO:0005525; GO:0006777; GO:0016829; GO:0046872; GO:0019008,"4 iron, 4 sulfur cluster binding; GTP binding; Mo-molybdopterin cofactor biosynthetic process; lyase activity; metal ion binding; molybdopterin synthase complex",PF06463;PF04055;,,,,,,,,,MOAA_CORGB,Corynebacterium glutamicum (strain R),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp68453_c0_seq1,266,43.2331,0.16360525,6,0,,,,,,,,,1.00E-20,CHOYP_PHUM_PHUM302370.1.1,,,,,,,,, comp68461_c0_seq1,409,39.3643,0.38618755,7,23,,4.00E-12,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp68467_c0_seq1,211,39.3365,0.99649712,0,7,,8.00E-11,Q91ZD1,Protein odd-skipped-related 2,Protein odd-skipped-related 2,GO:0060349; GO:0002062; GO:0042733; GO:0035115; GO:0035116; GO:0036023; GO:0061029; GO:0060322; GO:0001823; GO:0046872; GO:0001656; GO:0042474; GO:0000122; GO:0005634; GO:0042476; GO:0033687; GO:0060021; GO:0030501; GO:0050679; GO:2000543; GO:0045944; GO:0045893; GO:0048793; GO:0043565,"bone morphogenesis; chondrocyte differentiation; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic skeletal limb joint morphogenesis; eyelid development in camera-type eye; head development; mesonephros development; metal ion binding; metanephros development; middle ear morphogenesis; negative regulation of transcription from RNA polymerase II promoter; nucleus; odontogenesis; osteoblast proliferation; palate development; positive regulation of bone mineralization; positive regulation of epithelial cell proliferation; positive regulation of gastrulation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; pronephros development; sequence-specific DNA binding",PF00096;PF13912;,,,,,,,,,OSR2_MOUSE,Mus musculus (Mouse),"bone morphogenesis [GO:0060349]; cell differentiation [GO:0030154]; chondrocyte differentiation [GO:0002062]; embryo development [GO:0009790]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal joint development [GO:0072498]; embryonic skeletal joint morphogenesis [GO:0060272]; embryonic skeletal limb joint morphogenesis [GO:0036023]; embryonic skeletal system morphogenesis [GO:0048704]; eyelid development in camera-type eye [GO:0061029]; head development [GO:0060322]; mesonephros development [GO:0001823]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; osteoblast proliferation [GO:0033687]; palate development [GO:0060021]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gastrulation [GO:2000543]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephros development [GO:0048793]" comp68471_c0_seq1,287,64.4599,1.08424846,3,12,,2.00E-14,P0A3Z2,Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase I) (Aminopeptidase P I) (APP) (PEPP I) (X-Pro aminopeptidase I) (Xaa-Pro aminopeptidase I),Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase I) (Aminopeptidase P I) (APP) (PEPP I) (X-Pro aminopeptidase I) (Xaa-Pro aminopeptidase I),GO:0004177; GO:0009987; GO:0030145; GO:0008237; GO:0006508,aminopeptidase activity; cellular process; manganese ion binding; metallopeptidase activity; proteolysis,PF05195;PF00557;,,,,,,,,,AMPP1_STRLI,Streptomyces lividans, comp68499_c0_seq1,686,47.2303,0.86547235,8,53,,,,,,,,,1.00E-13,CHOYP_LOC100313559.1.1,,,,,,,,, comp68518_c0_seq1,240,43.3333,0.17852162,8,2,,2.00E-40,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-59,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp68530_c0_seq1,916,48.1441,0.925882,38,59,,1.00E-51,P61376,LIM/homeobox protein Lhx5 (LIM homeobox protein 5) (Homeobox protein LIM-2),LIM/homeobox protein Lhx5 (LIM homeobox protein 5) (Homeobox protein LIM-2),GO:0021846; GO:0021702; GO:0021937; GO:0021879; GO:0021766; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0021527; GO:0006351; GO:0008270,"cell proliferation in forebrain; cerebellar Purkinje cell differentiation; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; forebrain neuron differentiation; hippocampus development; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; spinal cord association neuron differentiation; transcription, DNA-dependent; zinc ion binding",PF00046;PF00412;,8.00E-55,CHOYP_LHX1.2.2,,,,,,,LHX5_RAT,Rattus norvegicus (Rat),"cell proliferation in forebrain [GO:0021846]; cerebellar Purkinje cell differentiation [GO:0021702]; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation [GO:0021937]; forebrain neuron differentiation [GO:0021879]; hippocampus development [GO:0021766]; positive regulation of transcription, DNA-templated [GO:0045893]; spinal cord association neuron differentiation [GO:0021527]; transcription, DNA-templated [GO:0006351]" comp68545_c0_seq1,462,39.3939,0.6177106,12,12,,6.00E-06,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,9.00E-13,CHOYP_LOC100695950.3.6,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp68551_c0_seq1,348,46.2644,0.76463855,5,0,,7.00E-26,Q5R522,"Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)","Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)",GO:0046872; GO:0005759; GO:0006470; GO:0004722,metal ion binding; mitochondrial matrix; protein dephosphorylation; protein serine/threonine phosphatase activity,PF00481;,,,,,,,,,PPM1K_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp68590_c0_seq1,248,53.2258,1.03107266,2,2,,2.00E-12,B2HGV4,Long-chain-fatty-acid--CoA ligase FadD15 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase),Long-chain-fatty-acid--CoA ligase FadD15 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase),GO:0005524; GO:0006633; GO:0001676; GO:0004467,ATP binding; fatty acid biosynthetic process; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;,,,,,,,,,FAC15_MYCMM,Mycobacterium marinum (strain ATCC BAA-535 / M),fatty acid biosynthetic process [GO:0006633] comp68591_c0_seq1,276,65.2174,0.9922314,0,28,,1.00E-15,O86428,Branched-chain-amino-acid aminotransferase (BCAT) (EC 2.6.1.42),Branched-chain-amino-acid aminotransferase (BCAT) (EC 2.6.1.42),GO:0052656; GO:0052654; GO:0052655; GO:0006520; GO:0009097; GO:0009098; GO:0009099,L-isoleucine transaminase activity; L-leucine transaminase activity; L-valine transaminase activity; cellular amino acid metabolic process; isoleucine biosynthetic process; leucine biosynthetic process; valine biosynthetic process,PF01063;,,,,,,,,,ILVE_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),aspartate biosynthetic process [GO:0006532]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099] comp68593_c0_seq1,308,45.1299,0.57602099,11,7,,4.00E-28,Q4V7P7,Sorting nexin-30,Sorting nexin-30,GO:0007154; GO:0005737; GO:0035091; GO:0015031,cell communication; cytoplasm; phosphatidylinositol binding; protein transport,PF03114;PF00787;,4.00E-34,CHOYP_LOC100376049.1.1,,,,,,,SNX30_XENLA,Xenopus laevis (African clawed frog),protein transport [GO:0015031] comp68616_c0_seq1,277,32.491,0.27470714,0,21,,7.00E-06,Q9H0W9,Ester hydrolase C11orf54 (EC 3.1.-.-),Ester hydrolase C11orf54 (EC 3.1.-.-),GO:0016788; GO:0005634; GO:0008270,"hydrolase activity, acting on ester bonds; nucleus; zinc ion binding",PF08925;,,,,,,,,,CK054_HUMAN,Homo sapiens (Human), comp68629_c0_seq1,237,72.1519,1.04216415,0,16,,6.00E-10,Q2S8F7,Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase),Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase),GO:0005524; GO:0004357; GO:0006750,ATP binding; glutamate-cysteine ligase activity; glutathione biosynthetic process,PF04262;,,,,,,,,,GSH1_HAHCH,Hahella chejuensis (strain KCTC 2396),glutathione biosynthetic process [GO:0006750] comp68635_c0_seq1,206,39.3204,0.63342986,0,3,,8.00E-06,O75197,Low-density lipoprotein receptor-related protein 5 (LRP-5),Low-density lipoprotein receptor-related protein 5 (LRP-5),GO:0044332; GO:0042813; GO:0017147; GO:0060612; GO:0009952; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042632; GO:0015026; GO:0048596; GO:0030326; GO:0060059; GO:0006897; GO:0005783; GO:0001702; GO:0006007; GO:0016021; GO:0045668; GO:0071901; GO:0002076; GO:0005886; GO:0045600; GO:0002053; GO:0045840; GO:0045944; GO:0043235; GO:0008217; GO:0060828; GO:0061178; GO:0061304,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; Wnt-protein binding; adipose tissue development; anterior/posterior pattern specification; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cholesterol homeostasis; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic limb morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; gastrulation with mouth forming second; glucose catabolic process; integral to membrane; negative regulation of osteoblast differentiation; negative regulation of protein serine/threonine kinase activity; osteoblast development; plasma membrane; positive regulation of fat cell differentiation; positive regulation of mesenchymal cell proliferation; positive regulation of mitosis; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of blood pressure; regulation of canonical Wnt receptor signaling pathway; regulation of insulin secretion involved in cellular response to glucose stimulus; retinal blood vessel morphogenesis,PF00057;PF00058;,,,,,,,,,LRP5_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp68691_c0_seq1,203,40.8867,0.47720456,5,46,,7.00E-06,Q54LN4,Gamma-glutamyl hydrolase A (EC 3.4.19.9) (Conjugase A) (GH A) (Gamma-Glu-X carboxypeptidase A),Gamma-glutamyl hydrolase A (EC 3.4.19.9) (Conjugase A) (GH A) (Gamma-Glu-X carboxypeptidase A),GO:0005618; GO:0005615; GO:0034722; GO:0006541; GO:0008242,cell wall; extracellular space; gamma-glutamyl-peptidase activity; glutamine metabolic process; omega peptidase activity,PF07722;,,,,,,,,,GGHA_DICDI,Dictyostelium discoideum (Slime mold),glutamine metabolic process [GO:0006541]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900] comp68707_c0_seq1,213,42.2535,0.52866778,3,6,,7.00E-22,Q5F364,Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane",PF00664;PF00005;,,,,,,,,,MRP1_CHICK,Gallus gallus (Chicken), comp68726_c0_seq1,520,37.6923,0.32549058,21,29,,2.00E-33,Q8NFA0,Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),GO:0005794; GO:0005509; GO:0008234; GO:0016020; GO:0016579; GO:0004221; GO:0006511,Golgi apparatus; calcium ion binding; cysteine-type peptidase activity; membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF06337;PF13202;PF14836;PF00443;,1.00E-31,CHOYP_UBP32.1.1,,,,,,,UBP32_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp68727_c0_seq1,261,46.3602,0.50137423,5,0,,6.00E-15,O95544,NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase),NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase),GO:0005524; GO:0046034; GO:0019674; GO:0003951; GO:0006741; GO:0005829; GO:0046872; GO:0006767,ATP binding; ATP metabolic process; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; cytosol; metal ion binding; water-soluble vitamin metabolic process,PF01513;,1.00E-20,CHOYP_LOC100875114.1.1,,,,,,,NADK_HUMAN,Homo sapiens (Human),ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310] comp68766_c0_seq1,234,42.3077,0.57552071,2,17,,7.00E-14,Q6ZR37,Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7),Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,1.00E-14,CHOYP_LOC577927.1.1,,,,,,,PKHG7_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp68778_c0_seq1,238,45.3782,0.16415125,7,0,,,,,,,,,,,1.00E-31,ruditapes_lrc19277,,,,,,, comp68778_c1_seq1,248,43.1452,0.43962579,6,0,,,,,,,,,,,1.00E-36,ruditapes_lrc31629,,,,,,, comp68848_c0_seq1,277,42.9603,0.55632515,12,0,,6.00E-23,Q9UNQ0,ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338),ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338),GO:0005524; GO:0006879; GO:0015232; GO:0016021; GO:0005886; GO:0042803; GO:0046415; GO:0008559,ATP binding; cellular iron ion homeostasis; heme transporter activity; integral to membrane; plasma membrane; protein homodimerization activity; urate metabolic process; xenobiotic-transporting ATPase activity,PF01061;PF00005;,7.00E-18,CHOYP_ABCG2.1.1,,,,,,,ABCG2_HUMAN,Homo sapiens (Human),cellular iron ion homeostasis [GO:0006879]; cellular response to dexamethasone stimulus [GO:0071549]; drug export [GO:0046618]; embryonic process involved in female pregnancy [GO:0060136]; response to drug [GO:0042493]; response to folic acid [GO:0051593]; response to iron ion [GO:0010039]; transport [GO:0006810]; urate metabolic process [GO:0046415] comp68864_c0_seq1,303,45.8746,1.33334786,11,15,,4.00E-23,Q13360,Zinc finger protein 177,Zinc finger protein 177,GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;PF13465;,,,,,,,,,ZN177_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp68870_c0_seq1,245,61.2245,1.04980412,0,25,,2.00E-11,Q35136,Probable intron-encoded endonuclease 4 (EC 3.1.-.-),Probable intron-encoded endonuclease 4 (EC 3.1.-.-),GO:0042773; GO:0003677; GO:0008137; GO:0004519; GO:0016021; GO:0006314; GO:0031966; GO:0090305,ATP synthesis coupled electron transport; DNA binding; NADH dehydrogenase (ubiquinone) activity; endonuclease activity; integral to membrane; intron homing; mitochondrial membrane; nucleic acid phosphodiester bond hydrolysis,PF00961;PF00361;PF00662;,,,,,,,,,IEND4_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),intron homing [GO:0006314] comp68878_c0_seq1,604,48.6755,0.92046085,20,27,,4.00E-64,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,9.00E-27,CHOYP_LOC100493788.1.1,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp68883_c0_seq1,256,42.9688,0.43932294,11,6,,1.00E-18,A2AFR3,FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso),FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso),GO:0005856; GO:0043197; GO:0005546; GO:0051835,"cytoskeleton; dendritic spine; phosphatidylinositol-4,5-bisphosphate binding; positive regulation of synapse structural plasticity",PF00373;PF00595;,,,,,,,,,FRPD4_MOUSE,Mus musculus (Mouse),positive regulation of synapse structural plasticity [GO:0051835] comp68887_c0_seq1,505,46.5347,0.62560245,16,13,,3.00E-62,Q9UL03,Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1),Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1),GO:0015629; GO:0032039; GO:0016180; GO:0004888,actin cytoskeleton; integrator complex; snRNA processing; transmembrane signaling receptor activity,PF15300;PF13519;,4.00E-49,CHOYP_INT6.1.1,,,,,,,INT6_HUMAN,Homo sapiens (Human),snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795] comp68911_c0_seq1,227,42.7313,0.97188587,0,4,,1.00E-15,P20678,Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (Cytochrome P450 PCHP7),Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (Cytochrome P450 PCHP7),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2H2_CHICK,Gallus gallus (Chicken),epoxygenase P450 pathway [GO:0019373] comp68927_c0_seq1,669,44.6936,0.65986359,36,3,,9.00E-17,Q6KEQ9,Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X),Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X),GO:0005509; GO:0007156; GO:0016021; GO:0010923; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; negative regulation of phosphatase activity; plasma membrane,PF00028;PF08266;PF08374;,,,,,,,,,PC11X_PIG,Sus scrofa (Pig),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of phosphatase activity [GO:0010923] comp6892_c0_seq1,260,41.1538,0.28064931,6,1,,8.00E-08,A9GP79,Urease accessory protein UreD,Urease accessory protein UreD,GO:0005737; GO:0016151; GO:0006807,cytoplasm; nickel cation binding; nitrogen compound metabolic process,PF01774;,,,,,,,,,URED_SORC5,Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)),nitrogen compound metabolic process [GO:0006807] comp68931_c0_seq1,562,44.6619,0.22613541,4,33,,1.00E-27,Q6ZVD8,PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like),PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like),GO:0038095; GO:0005829; GO:0007173; GO:0008543; GO:0045087; GO:0046872; GO:0048011; GO:0005634; GO:0048015; GO:0001917; GO:0042622; GO:0006470; GO:0004722,Fc-epsilon receptor signaling pathway; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; metal ion binding; neurotrophin TRK receptor signaling pathway; nucleus; phosphatidylinositol-mediated signaling; photoreceptor inner segment; photoreceptor outer segment membrane; protein dephosphorylation; protein serine/threonine phosphatase activity,PF13855;PF00481;,4.00E-18,CHOYP_BRAFLDRAFT_214316.1.1,,,,,,,PHLP2_HUMAN,Homo sapiens (Human),hippocampus development [GO:0021766] comp68936_c0_seq1,347,40.0576,0.66076498,24,3,,1.00E-08,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,3.00E-11,CHOYP_RN213.12.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp68951_c1_seq1,456,41.2281,0.67358601,8,23,,2.00E-64,Q1JQ66,Solute carrier family 35 member E3,Solute carrier family 35 member E3,GO:0016021,integral to membrane,PF03151;,2.00E-60,CHOYP_S35E3.1.1,,,,,,,S35E3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp68968_c0_seq1,406,37.4384,0.56410599,13,3,,7.00E-22,P40506,Phosphopantothenate--cysteine ligase CAB2 (EC 6.3.2.5) (Coenzyme A biosynthesis protein 2) (Phosphopantothenoylcysteine synthetase) (PPC synthetase),Phosphopantothenate--cysteine ligase CAB2 (EC 6.3.2.5) (Coenzyme A biosynthesis protein 2) (Phosphopantothenoylcysteine synthetase) (PPC synthetase),GO:0015937; GO:0005737; GO:0005634; GO:0004632,coenzyme A biosynthetic process; cytoplasm; nucleus; phosphopantothenate--cysteine ligase activity,PF04127;,7.00E-14,CHOYP_BRAFLDRAFT_282135.1.1,,,,,,,PPCS_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),coenzyme A biosynthetic process [GO:0015937] comp68969_c0_seq1,310,43.871,0.47244415,7,0,,1.00E-18,Q9LMP1,Wall-associated receptor kinase 2 (EC 2.7.11.-),Wall-associated receptor kinase 2 (EC 2.7.11.-),GO:0005524; GO:0005509; GO:0009992; GO:0016021; GO:0009311; GO:0030247; GO:0004674; GO:0009751; GO:0009826,ATP binding; calcium ion binding; cellular water homeostasis; integral to membrane; oligosaccharide metabolic process; polysaccharide binding; protein serine/threonine kinase activity; response to salicylic acid stimulus; unidimensional cell growth,PF07645;PF13947;PF07714;,9.00E-17,CHOYP_YR826.1.1,,,,,,,WAK2_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell surface receptor signaling pathway [GO:0007166]; cellular water homeostasis [GO:0009992]; oligosaccharide metabolic process [GO:0009311]; response to salicylic acid [GO:0009751]; unidimensional cell growth [GO:0009826] comp68987_c0_seq1,278,43.5252,1.40674089,5,0,,2.00E-11,Q8K135,Dyslexia-associated protein KIAA0319-like protein,Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR),GO:0031410; GO:0016021,cytoplasmic vesicle; integral to membrane,,,,,,,,,,K319L_MOUSE,Mus musculus (Mouse), comp69021_c0_seq1,286,61.5385,1.22651072,0,24,,1.00E-21,Q9EVR0,L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27),L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27),GO:0004459; GO:0044262; GO:0005737; GO:0006096,L-lactate dehydrogenase activity; cellular carbohydrate metabolic process; cytoplasm; glycolysis,PF02866;PF00056;,,,,,,,,,LDH_SELRU,Selenomonas ruminantium,carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752] comp69027_c0_seq1,217,44.2396,0.47392311,12,12,,8.00E-17,Q5BJW3,Protein TEX261,Protein TEX261,GO:0016021; GO:0043065,integral to membrane; positive regulation of apoptotic process,PF04148;,,,,,,,,,TX261_RAT,Rattus norvegicus (Rat),ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of apoptotic process [GO:0043065] comp69051_c0_seq1,224,68.3036,1.07768142,0,2,,1.00E-29,A1WBK4,Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT),Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT),GO:0005524; GO:0015937; GO:0005737; GO:0004595,ATP binding; coenzyme A biosynthetic process; cytoplasm; pantetheine-phosphate adenylyltransferase activity,PF01467;,,,,,,,,,COAD_ACISJ,Acidovorax sp. (strain JS42),coenzyme A biosynthetic process [GO:0015937] comp69088_c1_seq1,289,43.9446,0.57540371,9,3,,6.00E-23,Q80Y50,Calmodulin-binding transcription activator 2,Calmodulin-binding transcription activator 2,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03859;PF01833;,4.00E-52,CHOYP_CMTA1.2.2,,,,,,,CMTA2_MOUSE,Mus musculus (Mouse),cardiac muscle hypertrophy in response to stress [GO:0014898]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp69091_c1_seq1,486,44.4444,0.54507334,23,16,,3.00E-09,P0C1X8,AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1),AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1),GO:0035612; GO:0005524; GO:0005112; GO:0031252; GO:0071439; GO:0005905; GO:0006897; GO:0019897; GO:0045747; GO:0046777; GO:0004674; GO:0050821; GO:2000369; GO:0032880; GO:0043195,AP-2 adaptor complex binding; ATP binding; Notch binding; cell leading edge; clathrin complex; coated pit; endocytosis; extrinsic to plasma membrane; positive regulation of Notch signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity; protein stabilization; regulation of clathrin-mediated endocytosis; regulation of protein localization; terminal bouton,PF00069;,6.00E-22,CHOYP_AAK1.1.1,,,,,,,AAK1_RAT,Rattus norvegicus (Rat),endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of protein localization [GO:0032880] comp69105_c1_seq1,680,40.8824,0.5999702,14,35,,8.00E-53,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp69111_c0_seq1,280,49.2857,1.01101819,2,20,,9.00E-26,Q8BGN2,UPF0462 protein C4orf33 homolog,UPF0462 protein C4orf33 homolog,,,,8.00E-11,CHOYP_LOC101422627.1.1,,,,,,,CD033_MOUSE,Mus musculus (Mouse), comp69111_c1_seq1,269,46.4684,1.10770762,3,0,,,,,,,,,4.00E-14,CHOYP_NEMVEDRAFT_V1G110064.1.1,,,,,,,,, comp69158_c0_seq1,546,45.2381,0.26623647,18,0,,3.00E-53,Q8TD19,Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8),Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8),GO:0005524; GO:0051301; GO:0005829; GO:0046872; GO:0005739; GO:0007067; GO:0007077; GO:0005634; GO:0004674,ATP binding; cell division; cytosol; metal ion binding; mitochondrion; mitosis; mitotic nuclear envelope disassembly; nucleus; protein serine/threonine kinase activity,PF00069;PF00415;,4.00E-50,CHOYP_NEK9.1.1,,,,,,,NEK9_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; protein phosphorylation [GO:0006468] comp69171_c0_seq1,480,40.4167,0.73571826,0,0,,,,,,,,,,,7.00E-12,ruditapes2_c1331,,,,,,, comp69174_c0_seq1,273,49.0842,0.67202685,5,18,,,,,,,,,3.00E-15,CHOYP_MYO22.2.2,,,,,,,,, comp6917_c0_seq1,203,64.532,1.1444878,0,3,,9.00E-16,P52965,Putative pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-),Putative pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-),GO:0051539; GO:0022900; GO:0005506; GO:0009399; GO:0016903; GO:0030976,"4 iron, 4 sulfur cluster binding; electron transport chain; iron ion binding; nitrogen fixation; oxidoreductase activity, acting on the aldehyde or oxo group of donors; thiamine pyrophosphate binding",PF10371;PF17147;PF01558;PF01855;PF02775;,,,,,,,,,NIFJ_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),electron transport chain [GO:0022900]; nitrogen fixation [GO:0009399]; response to oxidative stress [GO:0006979] comp69203_c0_seq1,569,39.5431,0.31541599,18,0,,1.00E-13,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp69230_c0_seq1,413,44.3099,0.56712661,9,42,,8.00E-32,P58027,Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A),Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A),GO:0042420; GO:0016021; GO:0005741; GO:0042135; GO:0016491,dopamine catabolic process; integral to membrane; mitochondrial outer membrane; neurotransmitter catabolic process; oxidoreductase activity,PF01593;,,,,,,,,,AOFA_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),dopamine catabolic process [GO:0042420]; neurotransmitter catabolic process [GO:0042135] comp69258_c0_seq2,642,44.081,0.58015178,18,11,,1.00E-07,Q9C0G0,Zinc finger protein 407,Zinc finger protein 407,GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",,,,,,,,,,ZN407_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp69266_c0_seq1,220,40,0.59028997,1,21,,2.00E-13,Q6P3H7,Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4),Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4),GO:0033186; GO:0006260; GO:0035098; GO:0007049; GO:0031497; GO:0006338; GO:0006355; GO:0006351,"CAF-1 complex; DNA replication; ESC/E(Z) complex; cell cycle; chromatin assembly; chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12265;PF00400;,,,,,,,,,RBBP4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; chromatin remodeling [GO:0006338]; DNA replication [GO:0006260]; fin regeneration [GO:0031101]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp69272_c0_seq1,545,46.6055,0.54929762,2,29,,5.00E-10,Q0KK55,Protein very KIND (KIND domain-containing protein 1) (Kinase non-catalytic C-lobe domain-containing protein 1) (Ras-GEF domain-containing family member 2),Protein very KIND (KIND domain-containing protein 1) (Kinase non-catalytic C-lobe domain-containing protein 1) (Ras-GEF domain-containing family member 2),GO:0005088; GO:0021707; GO:0030425; GO:0032045; GO:0043025; GO:0001934; GO:0004674; GO:0048814; GO:0051056; GO:0007264,Ras guanyl-nucleotide exchange factor activity; cerebellar granule cell differentiation; dendrite; guanyl-nucleotide exchange factor complex; neuronal cell body; positive regulation of protein phosphorylation; protein serine/threonine kinase activity; regulation of dendrite morphogenesis; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF16474;PF00617;PF00618;,,,,,,,,,VKIND_MOUSE,Mus musculus (Mouse),cerebellar granule cell differentiation [GO:0021707]; positive regulation of protein phosphorylation [GO:0001934]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; small GTPase mediated signal transduction [GO:0007264] comp69290_c0_seq1,346,43.3526,0.43213312,9,20,,2.00E-39,Q12756,Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104),Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104),GO:0005524; GO:0008089; GO:0008219; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0003774; GO:0043005; GO:0043025; GO:0005634; GO:0005543,ATP binding; anterograde axon cargo transport; cell death; cytoplasm; kinesin complex; microtubule; microtubule motor activity; motor activity; neuron projection; neuronal cell body; nucleus; phospholipid binding,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,8.00E-44,CHOYP_LOC100875479.2.2,,,,,,,KIF1A_HUMAN,Homo sapiens (Human),anterograde axonal transport [GO:0008089] comp69292_c0_seq2,790,42.6582,0.45119502,25,0,,5.00E-35,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp69311_c1_seq1,239,56.4854,1.37024797,0,14,,3.00E-11,P44849,Uncharacterized sodium-dependent transporter HI_0736,Uncharacterized sodium-dependent transporter HI_0736,GO:0016021; GO:0005328; GO:0005886,integral to membrane; neurotransmitter:sodium symporter activity; plasma membrane,PF00209;,,,,,,,,,Y736_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),transport [GO:0006810] comp69314_c0_seq1,237,43.038,0.29359075,7,10,,3.00E-11,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,3.00E-15,CHOYP_LOC100056407.1.1,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp69323_c0_seq1,291,60.8247,1.10319177,0,21,,2.00E-31,Q0WM29,"Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MM-ALDH) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member B2)","Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MM-ALDH) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member B2)",GO:0005507; GO:0004491; GO:0005739; GO:0006979,copper ion binding; methylmalonate-semialdehyde dehydrogenase (acylating) activity; mitochondrion; response to oxidative stress,PF00171;,,,,,,,,,MMSA_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to oxidative stress [GO:0006979] comp69329_c0_seq1,278,46.4029,0.79632582,3,20,,2.00E-15,Q68LP1,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide),GO:0007219; GO:0005768; GO:0043123; GO:0004871; GO:0004842; GO:0008270,Notch signaling pathway; endosome; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding,PF00023;PF12796;PF06701;PF00569;,1.00E-14,CHOYP_LOC100374277.2.3,,,,,,,MIB2_RAT,Rattus norvegicus (Rat),Notch signaling pathway [GO:0007219] comp69341_c0_seq1,256,45.3125,0.46182196,5,0,,1.00E-18,Q8IYT3,Coiled-coil domain-containing protein 170,Coiled-coil domain-containing protein 170,,,,4.00E-26,CHOYP_VATB.2.2,,,,,,,CC170_HUMAN,Homo sapiens (Human), comp69355_c0_seq1,314,42.9936,0.55312238,3,34,,2.00E-24,Q96MW5,Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8),Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8),GO:0000139; GO:0017119; GO:0015031,Golgi membrane; Golgi transport complex; protein transport,PF04124;,2.00E-20,CHOYP_COG8.1.1,,,,,,,COG8_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] comp69361_c1_seq1,437,45.3089,1.34068654,7,26,,9.00E-27,P20905,5-hydroxytryptamine receptor 1 (5-HT receptor) (5HT-dro) (Serotonin receptor 1),5-hydroxytryptamine receptor 1 (5-HT receptor) (5HT-dro) (Serotonin receptor 1),GO:0007192; GO:0004952; GO:0007212; GO:0060180; GO:0016021; GO:0005887; GO:0016543; GO:0016546; GO:0016545; GO:0004993,"adenylate cyclase-activating serotonin receptor signaling pathway; dopamine neurotransmitter receptor activity; dopamine receptor signaling pathway; female mating behavior; integral to membrane; integral to plasma membrane; male courtship behavior, orientation prior to leg tapping and wing vibration; male courtship behavior, proboscis-mediated licking; male courtship behavior, veined wing vibration; serotonin receptor activity",PF00001;,,,,,,,,,5HT1R_DROME,Drosophila melanogaster (Fruit fly),"adenylate cyclase-activating serotonin receptor signaling pathway [GO:0007192]; courtship behavior [GO:0007619]; female mating behavior [GO:0060180]; male courtship behavior, orientation prior to leg tapping and wing vibration [GO:0016543]; male courtship behavior, proboscis-mediated licking [GO:0016546]; male courtship behavior, veined wing vibration [GO:0016545]; male mating behavior [GO:0060179]; serotonin receptor signaling pathway [GO:0007210]" comp69373_c0_seq2,441,43.5374,0.33806992,7,19,,2.00E-52,Q9V3L1,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)],Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)],GO:0000137; GO:0000139; GO:0016055; GO:0015016; GO:0005783; GO:0007427; GO:0008543; GO:0006024; GO:0007507; GO:0015014; GO:0030210; GO:0016787; GO:0008587; GO:0007474; GO:0016021; GO:0048312; GO:0007509; GO:0007428; GO:0060828; GO:0090097; GO:0045570; GO:0007367; GO:0048488,"Golgi cis cisterna; Golgi membrane; Wnt receptor signaling pathway; [heparan sulfate]-glucosamine N-sulfotransferase activity; endoplasmic reticulum; epithelial cell migration, open tracheal system; fibroblast growth factor receptor signaling pathway; glycosaminoglycan biosynthetic process; heart development; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin biosynthetic process; hydrolase activity; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; intracellular distribution of mitochondria; mesoderm migration involved in gastrulation; primary branching, open tracheal system; regulation of canonical Wnt receptor signaling pathway; regulation of decapentaplegic signaling pathway; regulation of imaginal disc growth; segment polarity determination; synaptic vesicle endocytosis",PF12062;PF00685;,7.00E-27,CHOYP_NDST.1.1,,,,,,,NDST_DROME,Drosophila melanogaster (Fruit fly),"cell surface receptor signaling pathway [GO:0007166]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; intracellular distribution of mitochondria [GO:0048312]; mesoderm migration involved in gastrulation [GO:0007509]; primary branching, open tracheal system [GO:0007428]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of decapentaplegic signaling pathway [GO:0090097]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; synaptic vesicle endocytosis [GO:0048488]; Wnt signaling pathway [GO:0016055]" comp69375_c0_seq1,224,47.7679,1.11558287,1,9,,7.00E-08,Q8WXD0,Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2),Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2),GO:0007189; GO:0007193; GO:0016021; GO:0008584; GO:0043066; GO:0008285; GO:0001556; GO:0017046; GO:0005886; GO:0030819; GO:0016500,adenylate cyclase-activating G-protein coupled receptor signaling pathway; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; integral to membrane; male gonad development; negative regulation of apoptotic process; negative regulation of cell proliferation; oocyte maturation; peptide hormone binding; plasma membrane; positive regulation of cAMP biosynthetic process; protein-hormone receptor activity,PF00001;PF00057;PF13855;,,,,,,,,,RXFP2_HUMAN,Homo sapiens (Human),adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; male gonad development [GO:0008584]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; oocyte maturation [GO:0001556]; positive regulation of cAMP biosynthetic process [GO:0030819] comp69408_c0_seq1,470,49.1489,0.46093253,18,24,,6.00E-49,Q8BRH4,Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog),Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog),GO:0003677; GO:0042800; GO:0035097; GO:0035556; GO:0006355; GO:0006351; GO:0008270,"DNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase complex; intracellular signal transduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,2.00E-84,CHOYP_LOC591084.2.2,,,,,,,MLL3_MOUSE,Mus musculus (Mouse),"eyelid development in camera-type eye [GO:0061029]; histone methylation [GO:0016571]; multicellular organism growth [GO:0035264]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; single fertilization [GO:0007338]; transcription, DNA-templated [GO:0006351]" comp69430_c0_seq1,367,59.9455,1.00315933,2,22,,1.00E-19,A1TEL6,Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B),Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B),GO:0005524; GO:0016021; GO:0009405; GO:0018106; GO:0004721; GO:0000155; GO:0005886; GO:0006950; GO:0023014,ATP binding; integral to membrane; pathogenesis; peptidyl-histidine phosphorylation; phosphoprotein phosphatase activity; phosphorelay sensor kinase activity; plasma membrane; response to stress; signal transduction by phosphorylation,PF00672;PF02518;PF00512;,,,,,,,,,MPRB_MYCVP,Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1),pathogenesis [GO:0009405] comp69486_c0_seq1,208,41.8269,0.11224749,9,9,,3.00E-06,O35242,Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation),Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation),GO:0005123,death receptor binding,PF02138;PF02893;PF00400;,,,,,,,,,FAN_MOUSE,Mus musculus (Mouse),positive regulation of apoptotic process [GO:0043065] comp69498_c0_seq1,287,48.7805,0.47107503,5,10,,3.00E-13,Q7TT36,Probable G-protein coupled receptor 125,Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125),GO:0004930; GO:0009897; GO:0016021; GO:0007218,G-protein coupled receptor activity; external side of plasma membrane; integral to membrane; neuropeptide signaling pathway,PF00002;PF07679;PF13855;,,,,,,,,,GP125_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166] comp69500_c0_seq1,355,43.9437,0.3569547,9,33,,4.00E-44,Q5F389,WW domain-containing oxidoreductase (EC 1.1.1.-),WW domain-containing oxidoreductase (EC 1.1.1.-),GO:0016055; GO:0006915; GO:0005737; GO:0005634; GO:0016491,Wnt receptor signaling pathway; apoptotic process; cytoplasm; nucleus; oxidoreductase activity,PF00106;PF00397;,,,,,,,,,WWOX_CHICK,Gallus gallus (Chicken),apoptotic process [GO:0006915]; Wnt signaling pathway [GO:0016055] comp69504_c0_seq1,291,42.268,0.69487864,0,20,,4.00E-10,Q91VN0,Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),GO:0044332; GO:0042813; GO:0060612; GO:0060033; GO:0009952; GO:1902262; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042074; GO:0060764; GO:0042632; GO:0008203; GO:0015026; GO:0048596; GO:0042733; GO:0060059; GO:0006897; GO:0005783; GO:0035426; GO:0001702; GO:0016021; GO:0005739; GO:0002076; GO:0005886; GO:0033690; GO:0051091; GO:0045944; GO:0043235; GO:0042981; GO:0046850; GO:0045598; GO:0061178; GO:0030278; GO:0061304; GO:0035019,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; adipose tissue development; anatomical structure regression; anterior/posterior pattern specification; apoptotic process involved in patterning of blood vessels; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cell migration involved in gastrulation; cell-cell signaling involved in mammary gland development; cholesterol homeostasis; cholesterol metabolic process; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; extracellular matrix-cell signaling; gastrulation with mouth forming second; integral to membrane; mitochondrion; osteoblast development; plasma membrane; positive regulation of osteoblast proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of apoptotic process; regulation of bone remodeling; regulation of fat cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of ossification; retinal blood vessel morphogenesis; somatic stem cell maintenance,PF00057;PF00058;,,,,,,,,,LRP5_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp69512_c0_seq1,218,44.4954,0.55868523,1,0,,2.00E-10,Q3UTY6,Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4),Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4),GO:0048251; GO:0004222; GO:0001527,elastic fiber assembly; metalloendopeptidase activity; microfibril,PF05986;PF08686;PF00090;,,,,,,,,,THSD4_MOUSE,Mus musculus (Mouse),elastic fiber assembly [GO:0048251] comp69513_c0_seq1,677,42.2452,0.43110879,10,27,,1.00E-24,P12080,Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain],Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain],GO:0016324; GO:0007475; GO:0007411; GO:0007414; GO:0009925; GO:0007298; GO:0050839; GO:0007160; GO:0007427; GO:0035099; GO:0007157; GO:0008305; GO:0007229; GO:0016328; GO:0035160; GO:0045185; GO:0007494; GO:0016203; GO:0030239; GO:0004872; GO:0008360; GO:0051492; GO:0007435; GO:0042383; GO:0007608; GO:0007426,"apical plasma membrane; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; axonal defasciculation; basal plasma membrane; border follicle cell migration; cell adhesion molecule binding; cell-matrix adhesion; epithelial cell migration, open tracheal system; hemocyte migration; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; maintenance of protein location; midgut development; muscle attachment; myofibril assembly; receptor activity; regulation of cell shape; regulation of stress fiber assembly; salivary gland morphogenesis; sarcolemma; sensory perception of smell; tracheal outgrowth, open tracheal system",PF01839;PF00357;PF08441;,,,,,,,,,ITA2_DROME,Drosophila melanogaster (Fruit fly),"apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; epithelial cell migration, open tracheal system [GO:0007427]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; maintenance of protein location [GO:0045185]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; myofibril assembly [GO:0030239]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]" comp69515_c0_seq1,379,44.8549,0.84257793,11,19,,4.00E-61,Q5RGJ8,N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta],GO:0000139; GO:0003976; GO:0005509; GO:0030154; GO:0016021; GO:0005634,Golgi membrane; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; calcium ion binding; cell differentiation; integral to membrane; nucleus,PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;,1.00E-47,CHOYP_GNPTA.1.3,,,,,,,GNPTA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256] comp69525_c0_seq1,417,30.2158,0.42653307,4,8,,3.00E-07,P11369,Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element-1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease],LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)],GO:0003723; GO:0006278; GO:0003964; GO:0004519; GO:0046872; GO:0090305,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF08333;PF03372;PF00078;,,,2.00E-11,ruditapes_c19911,,,,,POL2_MOUSE,Mus musculus (Mouse),DNA recombination [GO:0006310] comp69549_c0_seq1,202,29.703,0,4,0,,,,,,,,,,,8.00E-13,ruditapes2_c1163,,,,,,, comp69574_c0_seq2,326,39.2638,0.57011744,0,0,,1.00E-15,Q5SQS7,SH2 domain-containing protein 4B,SH2 domain-containing protein 4B,,,PF00017;,,,,,,,,,SH24B_HUMAN,Homo sapiens (Human), comp69581_c0_seq1,291,46.7354,0.44358163,3,15,,9.00E-30,P59913,Protein-L-isoaspartate O-methyltransferase domain-containing protein 1,Protein-L-isoaspartate O-methyltransferase domain-containing protein 1,GO:0005737; GO:0004719,cytoplasm; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,,,,,,,,,,PCMD1_MOUSE,Mus musculus (Mouse), comp69626_c0_seq1,218,42.6606,0.53942022,4,9,,6.00E-24,Q16549,Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),GO:0030173; GO:0016486; GO:0006508; GO:0004252,integral to Golgi membrane; peptide hormone processing; proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,4.00E-20,CHOYP_PCSK7.1.1,,,,,,,PCSK7_HUMAN,Homo sapiens (Human),peptide hormone processing [GO:0016486]; protein processing [GO:0016485] comp69644_c0_seq1,273,53.8462,0.46793797,1,31,,9.00E-07,P35072,Transposable element Tcb1 transposase (Transposable element Barney transposase),Transposable element Tcb1 transposase (Transposable element Barney transposase),GO:0003677; GO:0015074; GO:0005634; GO:0004803; GO:0006313,"DNA binding; DNA integration; nucleus; transposase activity; transposition, DNA-mediated",PF01498;,,,,,,,,,TCB1_CAEBR,Caenorhabditis briggsae,"DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]" comp69650_c0_seq1,313,38.9776,0.53447354,2,11,,2.00E-25,Q8NG66,Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11),Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11),GO:0005524; GO:0031572; GO:0031573; GO:0007243; GO:0046872; GO:0005730; GO:0004674,ATP binding; G2 DNA damage checkpoint; intra-S DNA damage checkpoint; intracellular protein kinase cascade; metal ion binding; nucleolus; protein serine/threonine kinase activity,PF00069;,6.00E-32,CHOYP_BRAFLDRAFT_63676.1.1,,,,,,,NEK11_HUMAN,Homo sapiens (Human),G2 DNA damage checkpoint [GO:0031572]; histone phosphorylation [GO:0016572]; intracellular signal transduction [GO:0035556]; intra-S DNA damage checkpoint [GO:0031573]; mitotic cell cycle phase transition [GO:0044772]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle phase transition [GO:1901990] comp69664_c0_seq1,433,41.8014,0.49543643,19,18,,2.00E-19,Q14790,Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10],Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10],GO:0031265; GO:0030690; GO:0035666; GO:0006919; GO:0001525; GO:0044297; GO:0006921; GO:0071260; GO:0005813; GO:0097153; GO:0005829; GO:0031264; GO:0097191; GO:0007507; GO:0045087; GO:0097193; GO:0030225; GO:0045121; GO:0005741; GO:0019048; GO:0043124; GO:0001841; GO:0043005; GO:0070423; GO:0005634; GO:0043123; GO:0045651; GO:1900740; GO:0045862; GO:0051291; GO:0051603; GO:2001239; GO:0046677; GO:0032025; GO:0009409; GO:0032355; GO:0045471; GO:0032496; GO:0034612; GO:0097342; GO:0034138; GO:0034142,CD95 death-inducing signaling complex; Noc1p-Noc2p complex; TRIF-dependent toll-like receptor signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; angiogenesis; cell body; cellular component disassembly involved in execution phase of apoptosis; cellular response to mechanical stimulus; centrosome; cysteine-type endopeptidase activity involved in apoptotic process; cytosol; death-inducing signaling complex; extrinsic apoptotic signaling pathway; heart development; innate immune response; intrinsic apoptotic signaling pathway; macrophage differentiation; membrane raft; mitochondrial outer membrane; modulation by virus of host morphology or physiology; negative regulation of I-kappaB kinase/NF-kappaB cascade; neural tube formation; neuron projection; nucleotide-binding oligomerization domain containing signaling pathway; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of macrophage differentiation; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; positive regulation of proteolysis; protein heterooligomerization; proteolysis involved in cellular protein catabolic process; regulation of extrinsic apoptotic signaling pathway in absence of ligand; response to antibiotic; response to cobalt ion; response to cold; response to estradiol stimulus; response to ethanol; response to lipopolysaccharide; response to tumor necrosis factor; ripoptosome; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway,PF01335;,,,,,,,,,CASP8_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; protein heterooligomerization [GO:0051291]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necrotic cell death [GO:0010939]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] comp69670_c0_seq1,321,43.3022,0.66750233,8,6,,2.00E-26,Q8CB19,Putative homeodomain transcription factor 2,Putative homeodomain transcription factor 2,GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12129;,,,,,,,,,PHTF2_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp69715_c1_seq1,354,47.1751,0.51006154,6,21,,4.00E-11,Q9BYN7,Zinc finger protein 341,Zinc finger protein 341,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN341_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp69716_c0_seq1,251,41.8327,0.40064229,8,0,,4.00E-06,Q8IVV2,Lipoxygenase homology domain-containing protein 1,Lipoxygenase homology domain-containing protein 1,GO:0005262; GO:0050982; GO:0016020; GO:0007605; GO:0032420,calcium channel activity; detection of mechanical stimulus; membrane; sensory perception of sound; stereocilium,PF01477;,,,,,,,,,LOXH1_HUMAN,Homo sapiens (Human),detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605] comp69749_c0_seq1,294,47.9592,0.89575935,6,15,,2.00E-16,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,,,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp69752_c0_seq1,305,48.5246,0.44909674,18,10,,5.00E-15,O01761,Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),Muscle M-line assembly protein unc-89 (Uncoordinated protein 89),GO:0005524; GO:0031430; GO:0005089; GO:0005543; GO:0004672; GO:0035023; GO:0030241,ATP binding; M band; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein kinase activity; regulation of Rho protein signal transduction; skeletal muscle myosin thick filament assembly,PF00041;PF07679;PF00069;PF05177;PF00621;,,,,,,,,,UNC89_CAEEL,Caenorhabditis elegans,myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241] comp69779_c0_seq1,299,41.4716,0.4702247,1,26,,1.00E-14,Q16706,"Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)","Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)",GO:0000139; GO:0006491; GO:0030246; GO:0016799; GO:0001701; GO:0016021; GO:0001889; GO:0048286; GO:0006013; GO:0004572; GO:0007005; GO:0043687; GO:0018279; GO:0007585; GO:0007033; GO:0008270,"Golgi membrane; N-glycan processing; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; in utero embryonic development; integral to membrane; liver development; lung alveolus development; mannose metabolic process; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; mitochondrion organization; post-translational protein modification; protein N-linked glycosylation via asparagine; respiratory gaseous exchange; vacuole organization; zinc ion binding",PF09261;PF01074;PF07748;,,,,,,,,,MA2A1_HUMAN,Homo sapiens (Human),in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033] comp69793_c0_seq1,291,45.0172,0.68966332,18,0,,7.00E-16,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp69812_c0_seq2,622,43.0868,0.32992142,8,26,,5.00E-26,Q149N8,"E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)","E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)",GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0016874; GO:0000786; GO:0006334; GO:0005634; GO:0016567; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; ligase activity; nucleosome; nucleosome assembly; nucleus; protein ubiquitination; zinc ion binding,PF00271;PF00538;PF00176;,,,,,,,,,SHPRH_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] comp69826_c0_seq1,415,44.3373,0.34551696,26,5,,1.00E-53,Q7ZYC4,Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2),Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2),GO:0005524; GO:0005737; GO:0001676; GO:0004467,ATP binding; cytoplasm; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;,7.00E-14,CHOYP_LOC100372454.1.1,,,,,,,ACBG2_XENLA,Xenopus laevis (African clawed frog), comp6983_c0_seq1,270,39.6296,1.06238093,6,0,,5.00E-07,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp69840_c0_seq1,393,44.2748,0.2605837,2,0,,2.00E-17,Q9F234,Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II),Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II),GO:0030246; GO:0005975; GO:0032450,carbohydrate binding; carbohydrate metabolic process; maltose alpha-glucosidase activity,PF16338;PF17137;PF13802;PF01055;,,,,,,,,,AGL2_BACTQ,Bacillus thermoamyloliquefaciens, comp69840_c0_seq2,419,46.0621,0.27120258,2,7,,3.00E-34,Q9MYM4,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),GO:0030246; GO:0005975; GO:0060048; GO:0005765; GO:0032450; GO:0043587; GO:0043181; GO:0055010,carbohydrate binding; carbohydrate metabolic process; cardiac muscle contraction; lysosomal membrane; maltose alpha-glucosidase activity; tongue morphogenesis; vacuolar sequestering; ventricular cardiac muscle tissue morphogenesis,PF13802;PF01055;PF16863;PF00088;,,,,,,,,,LYAG_BOVIN,Bos taurus (Bovine),cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] comp69840_c1_seq1,324,44.4444,0.38515081,11,13,,2.00E-32,O04893,Alpha-glucosidase (EC 3.2.1.20) (Maltase),Alpha-glucosidase (EC 3.2.1.20) (Maltase),GO:0030246; GO:0005975; GO:0032450,carbohydrate binding; carbohydrate metabolic process; maltose alpha-glucosidase activity,PF13802;PF01055;PF16863;,2.00E-24,CHOYP_LOC100553663.1.1,,,,,,,AGLU_SPIOL,Spinacia oleracea (Spinach), comp69851_c1_seq1,291,61.1684,0.96444228,0,26,,2.00E-26,P45313,Probable arabinose 5-phosphate isomerase (API) (EC 5.3.1.13),Probable arabinose 5-phosphate isomerase (API) (EC 5.3.1.13),GO:0030554; GO:0019146; GO:0030246; GO:0005975; GO:0046872,adenyl nucleotide binding; arabinose-5-phosphate isomerase activity; carbohydrate binding; carbohydrate metabolic process; metal ion binding,PF00571;PF01380;,,,,,,,,,API_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),carbohydrate metabolic process [GO:0005975] comp69860_c1_seq1,238,43.2773,0.36076109,6,0,,1.00E-19,P51537,Myoglobin,Myoglobin,GO:0020037; GO:0046872; GO:0005344,heme binding; metal ion binding; oxygen transporter activity,PF01231;,,,,,,,,,MYG_HALMK,Haliotis madaka (Giant abalone) (Nordotis madaka), comp69881_c0_seq1,392,45.1531,0.51372883,6,25,,4.00E-36,B9VTT2,Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12),Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12),GO:0005096; GO:0005737; GO:0005925; GO:0008289; GO:0016020; GO:0043547; GO:0007165,GTPase activator activity; cytoplasm; focal adhesion; lipid binding; membrane; positive regulation of GTPase activity; signal transduction,PF00620;PF07647;PF01852;,5.00E-41,CHOYP_RHG07.1.1,,,,,,,RHG07_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] comp69892_c0_seq1,266,46.9925,0.54685873,14,0,,5.00E-18,Q8S920,Ubiquitin-conjugating enzyme E2 5A (EC 6.3.2.19) (Ubiquitin carrier protein 5a) (OsUBC5a) (Ubiquitin-protein ligase 5A),Ubiquitin-conjugating enzyme E2 5A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 5A) (Ubiquitin carrier protein 5a) (OsUBC5a) (Ubiquitin-protein ligase 5A),GO:0005524; GO:0004842,ATP binding; ubiquitin-protein ligase activity,PF00179;,4.00E-52,CHOYP_PHUM_PHUM044580.1.1,,,,,,,UBC5A_ORYSJ,Oryza sativa subsp. japonica (Rice),protein ubiquitination [GO:0016567] comp69941_c0_seq1,387,45.9948,1.22847831,9,28,,9.00E-60,Q92193,Actin (Fragment),Actin (Fragment),GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,2.00E-25,CHOYP_ACT1.4.7,6.00E-18,ruditapes_c127,,,,,ACT_CRAVI,Crassostrea virginica (Eastern oyster), comp69941_c1_seq1,265,39.6226,1.05724876,6,9,,2.00E-26,P10994,"Actin, alpha skeletal muscle (Fragment)","Actin, alpha skeletal muscle (Fragment)",GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,3.00E-16,CHOYP_ACT3.3.3,9.00E-14,ruditapes2_lrc4267,,,,,ACTS_PLEWA,Pleurodeles waltl (Iberian ribbed newt), comp69956_c0_seq1,970,41.7526,0.5130333,49,29,,3.00E-33,Q460N5,Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2),GO:0003950; GO:0005737; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"NAD+ ADP-ribosyltransferase activity; cytoplasm; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01661;PF00644;,3.00E-16,CHOYP_BRAFLDRAFT_91321.7.10,,,,,,,PAR14_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp69960_c0_seq1,210,42.8571,0.52125688,0,12,,,,,,,,,2.00E-17,CHOYP_LOC100376222.1.1,,,,,,,,, comp69967_c0_seq1,230,42.6087,0.86735056,5,8,,2.00E-28,Q9UKP4,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,6.00E-37,CHOYP_BRAFLDRAFT_85817.1.1,,,,,,,ATS7_HUMAN,Homo sapiens (Human),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; protein O-linked fucosylation [GO:0036066]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp70000_c0_seq1,262,45.8015,0.88059319,6,22,,2.00E-11,Q8K078,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0006811; GO:0005886; GO:0005215,integral to membrane; ion transport; plasma membrane; transporter activity,PF07648;PF03137;,,,,,,,,,SO4A1_MOUSE,Mus musculus (Mouse),organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] comp70017_c0_seq1,228,39.4737,0.57251101,2,16,,7.00E-06,Q8CFZ5,Solute carrier family 22 member 12 (Renal-specific transporter) (RST) (Urate anion exchanger 1),Solute carrier family 22 member 12 (Renal-specific transporter) (RST) (Urate anion exchanger 1),GO:0030165; GO:0016324; GO:0031526; GO:0016021; GO:0042493; GO:0046415; GO:0015143; GO:0015747,PDZ domain binding; apical plasma membrane; brush border membrane; integral to membrane; response to drug; urate metabolic process; urate transmembrane transporter activity; urate transport,PF00083;,,,,,,,,,S22AC_MOUSE,Mus musculus (Mouse),response to drug [GO:0042493]; sodium-independent organic anion transport [GO:0043252]; urate metabolic process [GO:0046415]; urate transport [GO:0015747] comp70060_c0_seq1,1220,46.4754,0.56783598,30,29,,6.00E-87,Q9BYT9,Anoctamin-3 (Transmembrane protein 16C),Anoctamin-3 (Transmembrane protein 16C),GO:0016021; GO:0034220; GO:0005886,integral to membrane; ion transmembrane transport; plasma membrane,PF16178;PF04547;,,,,,,,,,ANO3_HUMAN,Homo sapiens (Human),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; ion transmembrane transport [GO:0034220] comp70060_c0_seq2,626,47.1246,0.66376861,0,3,,2.00E-66,A2AHL1,Anoctamin-3 (Transmembrane protein 16C),Anoctamin-3 (Transmembrane protein 16C),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF16178;PF04547;,2.00E-55,CHOYP_TMEM16.1.2,,,,,,,ANO3_MOUSE,Mus musculus (Mouse),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048] comp70065_c0_seq1,1373,43.6271,0.5410182,54,45,,4.00E-51,Q9VC61,Protein CREBRF homolog,Protein CREBRF homolog,GO:0005634; GO:0042803; GO:0043565; GO:0003700; GO:0006351,"nucleus; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",,2.00E-14,CHOYP_LOC100114844.1.1,,,,,,,CRERF_DROME,Drosophila melanogaster (Fruit fly),"positive regulation of transcription, DNA-templated [GO:0045893]; regulation of multicellular organismal metabolic process [GO:0044246]; response to starvation [GO:0042594]; sleep [GO:0030431]; TORC1 signaling [GO:0038202]; transcription, DNA-templated [GO:0006351]" comp70087_c0_seq1,224,66.0714,1.07538908,0,14,,5.00E-39,Q475S5,Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS),Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS),GO:0005524; GO:0003723; GO:0005737; GO:0004831; GO:0006437,ATP binding; RNA binding; cytoplasm; tyrosine-tRNA ligase activity; tyrosyl-tRNA aminoacylation,PF01479;PF00579;,,,,,,,,,SYY_CUPPJ,Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134)),tyrosyl-tRNA aminoacylation [GO:0006437] comp70089_c0_seq1,343,44.898,0.69671478,8,19,,1.00E-15,B2RU80,Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP),Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP),GO:0001525; GO:0016021; GO:0035335; GO:0004725,angiogenesis; integral to membrane; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00041;PF00102;,,,,,,,,,PTPRB_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; dephosphorylation [GO:0016311] comp70096_c0_seq1,573,47.4695,0.78193351,15,18,,4.00E-22,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp70099_c0_seq2,1348,43.9911,0.55533478,19,19,,2.00E-91,Q9VY77,LIM domain-containing protein jub,LIM domain-containing protein jub,GO:0003779; GO:0005912; GO:0035329; GO:0007067; GO:0045572; GO:0071539; GO:0008270,actin binding; adherens junction; hippo signaling cascade; mitosis; positive regulation of imaginal disc growth; protein localization to centrosome; zinc ion binding,PF00412;,2.00E-90,CHOYP_LOC408431.1.1,,,,,,,AJUBA_DROME,Drosophila melanogaster (Fruit fly),hippo signaling [GO:0035329]; mitotic nuclear division [GO:0007067]; ovarian follicle cell development [GO:0030707]; positive regulation of imaginal disc growth [GO:0045572]; positive regulation of organ growth [GO:0046622]; protein localization to centrosome [GO:0071539] comp70101_c0_seq1,627,47.0494,1.07116732,25,6,,2.00E-18,Q5G267,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_MACMU,Macaca mulatta (Rhesus macaque),exocytosis [GO:0006887] comp70102_c0_seq1,225,45.3333,0.17438616,1,8,,1.00E-28,O70546,Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein),Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein),GO:0000978; GO:0060070; GO:0051213; GO:0007507; GO:0071558; GO:0035097; GO:0001701; GO:0048333; GO:0046872; GO:0001843; GO:0048570; GO:0003016; GO:0032525,RNA polymerase II core promoter proximal region sequence-specific DNA binding; canonical Wnt receptor signaling pathway; dioxygenase activity; heart development; histone demethylase activity (H3-K27 specific); histone methyltransferase complex; in utero embryonic development; mesodermal cell differentiation; metal ion binding; neural tube closure; notochord morphogenesis; respiratory system process; somite rostral/caudal axis specification,PF02373;PF13181;,6.00E-30,CHOYP_LOC100883412.1.1,,,,,,,KDM6A_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; cardiovascular system development [GO:0072358]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] comp70103_c0_seq1,211,45.9716,0.55790727,2,15,,5.00E-10,A2RT67,DENN domain-containing protein 3,DENN domain-containing protein 3,GO:0017112; GO:0044257; GO:0008333,Rab guanyl-nucleotide exchange factor activity; cellular protein catabolic process; endosome to lysosome transport,PF02141;,,,,,,,,,DEND3_MOUSE,Mus musculus (Mouse),cellular protein catabolic process [GO:0044257]; endosome to lysosome transport [GO:0008333] comp70115_c0_seq1,390,38.9744,0.44331357,9,32,,2.00E-09,B0V3H4,UPF0692 protein C19orf54 homolog,UPF0692 protein C19orf54 homolog,,,,,,,,,,,,CS054_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp70117_c0_seq1,286,44.4056,0.35696954,5,14,,1.00E-34,Q6ZS30,Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein),,,PF02138;PF15787;PF14844;PF00400;,1.00E-34,CHOYP_LOC580791.1.1,,,,,,,NBEL1_HUMAN,Homo sapiens (Human), comp70132_c0_seq1,532,44.1729,0.50451613,10,15,,9.00E-15,Q8BX70,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp70141_c0_seq1,258,44.5736,0.78628989,7,4,,2.00E-19,O83041,Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),GO:0004177; GO:0005737; GO:0006508,aminopeptidase activity; cytoplasm; proteolysis,PF00561;,,,,,,,,,PIP_PLEBO,Leptolyngbya boryana (Plectonema boryanum), comp70154_c0_seq1,315,39.6825,0.89037783,3,21,,5.00E-16,P24628,D(2) dopamine receptor A (D2R-A) (D2R 1),D(2) dopamine receptor A (D2R-A) (D2R 1),GO:0007195; GO:0004935; GO:0071875; GO:0004952; GO:0005887,adenylate cyclase-inhibiting dopamine receptor signaling pathway; adrenergic receptor activity; adrenergic receptor signaling pathway; dopamine neurotransmitter receptor activity; integral to plasma membrane,PF00001;,,,,,,,,,DRD2A_XENLA,Xenopus laevis (African clawed frog),adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195] comp70155_c1_seq1,233,39.9142,0.43698284,1,6,,1.00E-07,Q80WQ9,Zinc finger BED domain-containing protein 4,Zinc finger BED domain-containing protein 4,GO:0003677; GO:0005737; GO:0046872; GO:0005634,DNA binding; cytoplasm; metal ion binding; nucleus,PF05699;PF02892;,,,,,,,,,ZBED4_MOUSE,Mus musculus (Mouse),regulation of transcription from RNA polymerase II promoter [GO:0006357] comp70157_c0_seq1,211,64.9289,1.04592654,0,8,,1.00E-14,O86788,tRNA threonylcarbamoyladenosine biosynthesis protein TsaE (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE),tRNA threonylcarbamoyladenosine biosynthesis protein TsaE (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE),GO:0005524; GO:0005737; GO:0046872; GO:0070526,ATP binding; cytoplasm; metal ion binding; threonylcarbamoyladenosine biosynthetic process,PF02367;,,,,,,,,,Y4747_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),tRNA threonylcarbamoyladenosine modification [GO:0002949] comp70163_c0_seq1,344,47.9651,1.08199839,0,12,,1.00E-06,Q28EM7,Homeobox protein otx5 (Orthodenticle homolog 5),Homeobox protein otx5 (Orthodenticle homolog 5),GO:0009952; GO:0042706; GO:0005634; GO:0045872; GO:0045944; GO:0043565; GO:0003700; GO:0006351,"anterior/posterior pattern specification; eye photoreceptor cell fate commitment; nucleus; positive regulation of rhodopsin gene expression; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;PF03529;,6.00E-39,CHOYP_EMX1.1.2,,,,,,,OTX5_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"anterior/posterior pattern specification [GO:0009952]; eye photoreceptor cell fate commitment [GO:0042706]; positive regulation of rhodopsin gene expression [GO:0045872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp70174_c0_seq1,201,47.7612,0.4391413,2,0,,4.00E-20,Q86UP3,Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4),Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4),GO:0005634; GO:0043565; GO:0003700; GO:0006351; GO:0008270,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF00046;,3.00E-46,CHOYP_LOC100877335.1.1,,,,,,,ZFHX4_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp70176_c0_seq1,201,40.796,0.60228086,1,6,,1.00E-07,Q1RMW5,Growth factor receptor-bound protein 7 (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein),Growth factor receptor-bound protein 7 (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein),GO:0003723; GO:0042995; GO:0010494; GO:0005829; GO:0005925; GO:0017148; GO:0035091; GO:0005886; GO:0030335; GO:0007165; GO:0034063,RNA binding; cell projection; cytoplasmic stress granule; cytosol; focal adhesion; negative regulation of translation; phosphatidylinositol binding; plasma membrane; positive regulation of cell migration; signal transduction; stress granule assembly,PF08947;PF00169;PF00788;PF00017;,,,,,,,,,GRB7_BOVIN,Bos taurus (Bovine),negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; signal transduction [GO:0007165]; stress granule assembly [GO:0034063] comp7018_c0_seq1,215,45.5814,0.90302957,4,2,,,,,,,,,9.00E-15,CHOYP_PHUM_PHUM490910.1.1,,,,,,,,, comp70193_c0_seq1,490,44.4898,0.70261235,14,7,,4.00E-29,O00522,Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein),Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein),GO:0001525; GO:0045454; GO:0005911; GO:0005737; GO:0005874; GO:0008017; GO:0016525; GO:2000352; GO:0010596; GO:0001937; GO:0005546; GO:0005886; GO:0032092; GO:2000114; GO:0007264; GO:0005083,"angiogenesis; cell redox homeostasis; cell-cell junction; cytoplasm; microtubule; microtubule binding; negative regulation of angiogenesis; negative regulation of endothelial cell apoptotic process; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane; positive regulation of protein binding; regulation of establishment of cell polarity; small GTPase mediated signal transduction; small GTPase regulator activity",PF00373;PF16705;,,,,,,,,,KRIT1_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell redox homeostasis [GO:0045454]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of protein binding [GO:0032092]; regulation of establishment of cell polarity [GO:2000114]; small GTPase mediated signal transduction [GO:0007264] comp70199_c0_seq1,381,40.1575,0.59174246,11,10,,2.00E-35,Q9UNQ0,ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338),ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338),GO:0005524; GO:0006879; GO:0015232; GO:0016021; GO:0005886; GO:0042803; GO:0046415; GO:0008559,ATP binding; cellular iron ion homeostasis; heme transporter activity; integral to membrane; plasma membrane; protein homodimerization activity; urate metabolic process; xenobiotic-transporting ATPase activity,PF01061;PF00005;,2.00E-20,CHOYP_ABCG2.1.1,,,,,,,ABCG2_HUMAN,Homo sapiens (Human),cellular iron ion homeostasis [GO:0006879]; cellular response to dexamethasone stimulus [GO:0071549]; drug export [GO:0046618]; embryonic process involved in female pregnancy [GO:0060136]; response to drug [GO:0042493]; response to folic acid [GO:0051593]; response to iron ion [GO:0010039]; transport [GO:0006810]; urate metabolic process [GO:0046415] comp70200_c0_seq1,227,40.9692,0.42777566,3,15,,2.00E-11,Q28DZ1,Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA),Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA),GO:0005524; GO:0007252; GO:0008384; GO:0071356; GO:0005737; GO:0005634; GO:0045944; GO:0046982; GO:0042803,ATP binding; I-kappaB phosphorylation; IkappaB kinase activity; cellular response to tumor necrosis factor; cytoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; protein heterodimerization activity; protein homodimerization activity,PF00069;,,,,,,,,,IKKA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to tumor necrosis factor [GO:0071356]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp70250_c1_seq1,326,42.638,0.5542425,2,15,,,,,,,,,1.00E-15,CHOYP_LOC100900284.1.1,,,,,,,,, comp70259_c0_seq1,356,54.2135,1.07995666,0,27,,9.00E-17,P74068,Uncharacterized transporter sll1263,Uncharacterized transporter sll1263,GO:0008324; GO:0016021; GO:0005886,cation transmembrane transporter activity; integral to membrane; plasma membrane,PF01545;PF16916;,,,,,,,,,Y1263_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa),cadmium ion transmembrane transport [GO:0070574]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp70275_c0_seq1,559,45.4383,0.34982621,6,46,,4.00E-30,Q98T88,Twisted gastrulation protein homolog 1-A,Twisted gastrulation protein homolog 1-A,GO:0005576; GO:0007275,extracellular region; multicellular organismal development,PF04668;,8.00E-21,CHOYP_LOC100871815.1.1,,,,,,,TWS1A_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275] comp70276_c0_seq1,262,46.1832,0.51569379,2,19,,4.00E-23,Q68SA9,A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase),GO:0009986; GO:0004222; GO:0008237; GO:0005578; GO:0006508; GO:0008270,cell surface; metalloendopeptidase activity; metallopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,2.00E-37,CHOYP_BRAFLDRAFT_85817.1.1,,,,,,,ATS7_MOUSE,Mus musculus (Mouse),cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp70279_c0_seq1,408,41.9118,0.45444717,18,0,,7.00E-26,Q8NAA4,Autophagy-related protein 16-2 (APG16-like 2) (WD repeat-containing protein 80),Autophagy-related protein 16-2 (APG16-like 2) (WD repeat-containing protein 80),GO:0006914; GO:0005737; GO:0015031,autophagy; cytoplasm; protein transport,PF08614;PF00400;,,,,,,,,,A16L2_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; negative stranded viral RNA replication [GO:0039689]; protein transport [GO:0015031] comp70279_c1_seq1,343,40.2332,0.53846612,13,6,,3.00E-46,Q5I0B9,Autophagy-related protein 16 (APG16-like 1),Autophagy-related protein 16 (APG16-like 1),GO:0006914; GO:0005737; GO:0016020; GO:0015031,autophagy; cytoplasm; membrane; protein transport,PF08614;PF00400;,1.00E-29,CHOYP_BRAFLDRAFT_123636.1.1,,,,,,,ATG16_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),autophagosome assembly [GO:0000045]; negative stranded viral RNA replication [GO:0039689]; protein transport [GO:0015031] comp70290_c0_seq1,508,49.0157,0.33753446,12,24,,1.00E-71,Q5SQM0,Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like),GO:0005737; GO:0005874,cytoplasm; microtubule,PF12894;PF03451;PF00400;,3.00E-70,CHOYP_EMAL6.1.1,,,,,,,EMAL6_MOUSE,Mus musculus (Mouse), comp70315_c0_seq1,271,52.3985,0.65807348,2,13,,3.00E-08,P35556,Fibrillin-2,Fibrillin-2 [Cleaved into: Fibrillin-2 C-terminal peptide],GO:0060346; GO:0005509; GO:0030326; GO:0030198; GO:0005201; GO:0001527; GO:0030501; GO:0045669; GO:0035583,bone trabecula formation; calcium ion binding; embryonic limb morphogenesis; extracellular matrix organization; extracellular matrix structural constituent; microfibril; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; sequestering of TGFbeta in extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN2_HUMAN,Homo sapiens (Human),bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of TGFbeta in extracellular matrix [GO:0035583] comp70330_c0_seq1,244,46.3115,0.30721519,1,0,,2.00E-11,Q7TPQ9,Arrestin domain-containing protein 3,Arrestin domain-containing protein 3,GO:0005737; GO:0060613; GO:0031651; GO:0090327; GO:0044252; GO:0071879; GO:0043588; GO:0001659,cytoplasm; fat pad development; negative regulation of heat generation; negative regulation of locomotion involved in locomotory behavior; negative regulation of multicellular organismal metabolic process; positive regulation of adrenergic receptor signaling pathway; skin development; temperature homeostasis,PF02752;PF00339;,1.00E-13,CHOYP_LOC100176335.2.7,,,,,,,ARRD3_MOUSE,Mus musculus (Mouse),fat pad development [GO:0060613]; negative regulation of heat generation [GO:0031651]; negative regulation of locomotion involved in locomotory behavior [GO:0090327]; negative regulation of multicellular organismal metabolic process [GO:0044252]; positive regulation of adrenergic receptor signaling pathway [GO:0071879]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; skin development [GO:0043588]; temperature homeostasis [GO:0001659] comp70344_c0_seq1,540,60.1852,1.16807219,3,22,,7.00E-37,Q82KJ6,Ferrochelatase (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase),Ferrochelatase (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase),GO:0005737; GO:0004325; GO:0006783; GO:0046872,cytoplasm; ferrochelatase activity; heme biosynthetic process; metal ion binding,PF00762;,,,,,,,,,HEMH_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),heme biosynthetic process [GO:0006783] comp70376_c0_seq1,282,31.2057,0.14686225,7,4,,,,,,,,,5.00E-13,CHOYP_contig_017473,,,,,,,,, comp70378_c0_seq1,333,34.5345,0.30983582,4,26,,6.00E-13,Q9P2E5,Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase),Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase),GO:0032580; GO:0000139; GO:0050510; GO:0005975; GO:0030206; GO:0016021,Golgi cisterna membrane; Golgi membrane; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; integral to membrane,PF05679;,,,,,,,,,CHPF2_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206] comp70406_c0_seq1,266,46.9925,0.89001258,0,11,,6.00E-13,P51871,Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),GO:0070330; GO:0005789; GO:0020037; GO:0006954; GO:0005506; GO:0006691,aromatase activity; endoplasmic reticulum membrane; heme binding; inflammatory response; iron ion binding; leukotriene metabolic process,PF00067;,,,,,,,,,CP4F6_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691] comp70415_c0_seq1,272,64.3382,0.9984461,0,22,,2.00E-59,Q6AAW5,D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-),D-aminoacyl-tRNA deacylase (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase),GO:0019478; GO:0005737; GO:0016788,"D-amino acid catabolic process; cytoplasm; hydrolase activity, acting on ester bonds",PF02580;,,,,,,,,,DTD_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),D-amino acid catabolic process [GO:0019478] comp70415_c1_seq1,345,60.2899,0.96049664,0,15,,3.00E-11,Q6AAW4,UPF0678 fatty acid-binding protein-like protein PPA0347,UPF0678 fatty acid-binding protein-like protein PPA0347,GO:0006810,transport,PF08768;,,,,,,,,,Y347_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),transport [GO:0006810] comp70434_c0_seq1,206,65.0485,0.83078881,0,9,,5.00E-16,P37739,C4-dicarboxylate transport sensor protein DctS (EC 2.7.13.3),C4-dicarboxylate transport sensor protein DctS (EC 2.7.13.3),GO:0005524; GO:0016021; GO:0018106; GO:0000155; GO:0005886; GO:0006355; GO:0023014,"ATP binding; integral to membrane; peptidyl-histidine phosphorylation; phosphorelay sensor kinase activity; plasma membrane; regulation of transcription, DNA-dependent; signal transduction by phosphorylation",PF02518;PF00512;PF00989;,,,,,,,,,DCTS_RHOCA,Rhodobacter capsulatus (Rhodopseudomonas capsulata),"regulation of transcription, DNA-templated [GO:0006355]" comp70439_c0_seq1,236,52.9661,1.1179446,9,6,,7.00E-14,Q10133,GTP-binding protein rho2,GTP-binding protein rho2,GO:0005525; GO:0003924; GO:0032153; GO:0051286; GO:0005829; GO:0030950; GO:0071963; GO:0005634; GO:0005886; GO:0032949; GO:0030427; GO:0007264,GTP binding; GTPase activity; cell division site; cell tip; cytosol; establishment or maintenance of actin cytoskeleton polarity; establishment or maintenance of cell polarity regulating cell shape; nucleus; plasma membrane; regulation of alpha-glucan biosynthetic process; site of polarized growth; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RHO2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; regulation of alpha-glucan biosynthetic process [GO:0032949]; small GTPase mediated signal transduction [GO:0007264] comp70491_c0_seq1,264,43.9394,0.39814273,4,24,,2.00E-06,Q8NCU4,Coiled-coil domain-containing protein KIAA1407,Coiled-coil domain-containing protein 191,,,,,,,,,,,,K1407_HUMAN,Homo sapiens (Human), comp70502_c1_seq1,235,46.383,0.80001449,3,9,,,,,,,,,2.00E-24,CHOYP_LOC101165212.3.6,,,,,,,,, comp70504_c0_seq1,206,41.2621,0.91798172,0,0,,6.00E-14,P08575,Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45),Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45),GO:0042100; GO:0050853; GO:0030217; GO:0050852; GO:0007411; GO:0048539; GO:0051607; GO:0009897; GO:0005925; GO:0002244; GO:0002378; GO:0005887; GO:0045121; GO:0001915; GO:0006933; GO:0001960; GO:0006469; GO:0030890; GO:0042102; GO:0050857; GO:2000473; GO:0045860; GO:2000648; GO:0051726; GO:0051209; GO:0048864; GO:0005001,B cell proliferation; B cell receptor signaling pathway; T cell differentiation; T cell receptor signaling pathway; axon guidance; bone marrow development; defense response to virus; external side of plasma membrane; focal adhesion; hematopoietic progenitor cell differentiation; immunoglobulin biosynthetic process; integral to plasma membrane; membrane raft; negative regulation of T cell mediated cytotoxicity; negative regulation of cell adhesion involved in substrate-bound cell migration; negative regulation of cytokine-mediated signaling pathway; negative regulation of protein kinase activity; positive regulation of B cell proliferation; positive regulation of T cell proliferation; positive regulation of antigen receptor-mediated signaling pathway; positive regulation of hematopoietic stem cell migration; positive regulation of protein kinase activity; positive regulation of stem cell proliferation; regulation of cell cycle; release of sequestered calcium ion into cytosol; stem cell development; transmembrane receptor protein tyrosine phosphatase activity,PF12567;PF00041;PF12453;PF00102;,,,,,,,,,PTPRC_HUMAN,Homo sapiens (Human),B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; hematopoietic progenitor cell differentiation [GO:0002244]; immunoglobulin biosynthetic process [GO:0002378]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell proliferation [GO:0042102]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; release of sequestered calcium ion into cytosol [GO:0051209]; stem cell development [GO:0048864]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] comp70514_c0_seq1,396,46.7172,0.46893755,6,40,,6.00E-28,Q9ULH1,"Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)","Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)",GO:0008060; GO:0060271; GO:0005737; GO:0016020; GO:0005543; GO:0043547; GO:0032312; GO:0008270,ARF GTPase activator activity; cilium morphogenesis; cytoplasm; membrane; phospholipid binding; positive regulation of GTPase activity; regulation of ARF GTPase activity; zinc ion binding,PF12796;PF01412;PF00169;PF00018;,,,,,,,,,ASAP1_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; negative regulation of dendritic spine development [GO:0061000] comp70516_c0_seq1,276,48.1884,0.75170593,12,14,,2.00E-32,A8X2R1,"L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)","L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)",GO:0047545; GO:0005739,2-hydroxyglutarate dehydrogenase activity; mitochondrion,PF01266;,,,,,,,,,L2HDH_CAEBR,Caenorhabditis briggsae, comp70527_c1_seq1,206,66.9903,0.91788481,0,10,,4.00E-18,P65633,Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Component of peroxynitrite reductase/peroxidase complex) (Component of PNR/P) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDH component E2),,GO:0016209; GO:0045454; GO:0005618; GO:0005829; GO:0004148; GO:0004742; GO:0006096; GO:0040007; GO:0031405; GO:0009405; GO:0005886; GO:0045254; GO:0052572,antioxidant activity; cell redox homeostasis; cell wall; cytosol; dihydrolipoyl dehydrogenase activity; dihydrolipoyllysine-residue acetyltransferase activity; glycolysis; growth; lipoic acid binding; pathogenesis; plasma membrane; pyruvate dehydrogenase complex; response to host immune response,,,,,,,,,,ODO2_MYCTU,, comp70575_c0_seq1,242,59.0909,0.95295745,0,17,,5.00E-52,Q6A5P0,Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase),GO:0005524; GO:0005737; GO:0016260; GO:0097056; GO:0004828; GO:0006434,ATP binding; cytoplasm; selenocysteine biosynthetic process; selenocysteinyl-tRNA(Sec) biosynthetic process; serine-tRNA ligase activity; seryl-tRNA aminoacylation,PF02403;PF00587;,,,,,,,,,SYS_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] comp70583_c0_seq1,644,41.9255,0.46010866,28,5,,8.00E-69,O60427,Fatty acid desaturase 1 (EC 1.14.19.-) (Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase),Fatty acid desaturase 1 (EC 1.14.19.-) (Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase),GO:0000248; GO:0007568; GO:0036109; GO:0019369; GO:0007267; GO:0009267; GO:0005789; GO:0020037; GO:0046456; GO:0016021; GO:0005506; GO:0043651; GO:0005739; GO:0005634; GO:0008654; GO:0045595; GO:0006355; GO:0032868; GO:0014070; GO:0009744; GO:0033189; GO:0006636,"C-5 sterol desaturase activity; aging; alpha-linolenic acid metabolic process; arachidonic acid metabolic process; cell-cell signaling; cellular response to starvation; endoplasmic reticulum membrane; heme binding; icosanoid biosynthetic process; integral to membrane; iron ion binding; linoleic acid metabolic process; mitochondrion; nucleus; phospholipid biosynthetic process; regulation of cell differentiation; regulation of transcription, DNA-dependent; response to insulin stimulus; response to organic cyclic compound; response to sucrose stimulus; response to vitamin A; unsaturated fatty acid biosynthetic process",PF00173;PF00487;,9.00E-53,CHOYP_LOC100373185.1.1,,,,,,,FADS1_HUMAN,Homo sapiens (Human),"alpha-linolenic acid metabolic process [GO:0036109]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; icosanoid biosynthetic process [GO:0046456]; linoleic acid metabolic process [GO:0043651]; phospholipid biosynthetic process [GO:0008654]; regulation of cell differentiation [GO:0045595]; regulation of transcription, DNA-templated [GO:0006355]; unsaturated fatty acid biosynthetic process [GO:0006636]" comp70606_c0_seq1,472,49.3644,0.76740757,8,36,,2.00E-76,Q6GLD8,Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9),Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9),GO:0005524; GO:0008353; GO:0004693; GO:0005634; GO:0006355; GO:0006351,"ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein serine/threonine kinase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;,1.00E-49,CHOYP_CDK9.1.1,,,,,,,CDK9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp70644_c0_seq2,357,41.7367,0.58646256,5,3,,1.00E-37,Q96RR4,Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta),Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta),GO:0005524; GO:0000165; GO:0005509; GO:0019722; GO:0005516; GO:0004683; GO:0042995; GO:0005737; GO:0005634; GO:0045893; GO:0046777; GO:0004713; GO:0045859,"ATP binding; MAPK cascade; calcium ion binding; calcium-mediated signaling; calmodulin binding; calmodulin-dependent protein kinase activity; cell projection; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein tyrosine kinase activity; regulation of protein kinase activity",PF00069;,4.00E-35,CHOYP_CAMKK1.1.1,,,,,,,KKCC2_HUMAN,Homo sapiens (Human),"calcium-mediated signaling [GO:0019722]; MAPK cascade [GO:0000165]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein kinase activity [GO:0045859]" comp70650_c2_seq1,497,46.6801,0.70449247,16,29,,,,,,,,,2.00E-27,CHOYP_BRAFLDRAFT_71629.1.1,,,,,,,,, comp70658_c0_seq1,204,75.9804,1.26335481,0,2,,1.00E-07,A3Q5L8,Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B),Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B),GO:0005524; GO:0016021; GO:0009405; GO:0018106; GO:0004721; GO:0000155; GO:0005886; GO:0006950; GO:0023014,ATP binding; integral to membrane; pathogenesis; peptidyl-histidine phosphorylation; phosphoprotein phosphatase activity; phosphorelay sensor kinase activity; plasma membrane; response to stress; signal transduction by phosphorylation,PF00672;PF02518;PF00512;,,,,,,,,,MPRB_MYCSJ,Mycobacterium sp. (strain JLS),pathogenesis [GO:0009405] comp70671_c0_seq1,323,40.8669,0.6694279,4,0,,,,,,,,,1.00E-16,CHOYP_PLXB2.2.2,,,,,,,,, comp70702_c0_seq1,403,37.2208,0.87179102,5,37,,,,,,,,,,,2.00E-18,ruditapes_c10113,,,,,,, comp70705_c0_seq1,251,42.6295,0.90324014,0,21,,2.00E-08,Q8IYS1,Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2),GO:0016787,hydrolase activity,PF07687;PF01546;,,,,,,,,,P20D2_HUMAN,Homo sapiens (Human),proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268] comp70729_c1_seq1,266,43.985,1.18073603,0,21,,8.00E-11,Q86UD0,Suppressor APC domain-containing protein 2 (Tumor specificity and mitosis phase-dependent expression protein) (TS/MDEP) (p42.3),Suppressor APC domain-containing protein 2 (Tumor specificity and mitosis phase-dependent expression protein) (TS/MDEP) (p42.3),GO:0005737; GO:0005730,cytoplasm; nucleolus,,,,,,,,,,SAPC2_HUMAN,Homo sapiens (Human), comp70767_c1_seq1,364,32.967,0.30724138,6,11,,,,,,,,,1.00E-34,CHOYP_WU_FC28F08.1.1,,,,,,,,, comp70788_c0_seq1,569,39.5431,0.80056427,2,2,,6.00E-120,Q3SZ41,Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa),Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa),GO:0030183; GO:0002193; GO:0000978; GO:0001077; GO:0000979; GO:0001525; GO:0060844; GO:0036302; GO:0009912; GO:0097101; GO:0072554; GO:0001974; GO:0003214; GO:0003682; GO:0005737; GO:0042742; GO:0035912; GO:0003160; GO:0009957; GO:0003198; GO:0048820; GO:0006959; GO:0002437; GO:0072602; GO:0030216; GO:0060716; GO:0008285; GO:0030279; GO:0000122; GO:0005730; GO:0005634; GO:0003151; GO:0021983; GO:0030513; GO:1901186; GO:0060045; GO:2000138; GO:1901189; GO:0007221; GO:0048505; GO:0003256; GO:0048733; GO:0035019; GO:0005667; GO:0003222,B cell differentiation; MAML1-RBP-Jkappa- ICN1 complex; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; angiogenesis; arterial endothelial cell fate commitment; atrioventricular canal development; auditory receptor cell fate commitment; blood vessel endothelial cell fate specification; blood vessel lumenization; blood vessel remodeling; cardiac left ventricle morphogenesis; chromatin binding; cytoplasm; defense response to bacterium; dorsal aorta morphogenesis; endocardium morphogenesis; epidermal cell fate specification; epithelial to mesenchymal transition involved in endocardial cushion formation; hair follicle maturation; humoral immune response; inflammatory response to antigenic stimulus; interleukin-4 secretion; keratinocyte differentiation; labyrinthine layer blood vessel development; negative regulation of cell proliferation; negative regulation of ossification; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; outflow tract morphogenesis; pituitary gland development; positive regulation of BMP signaling pathway; positive regulation of ERBB signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation involved in heart morphogenesis; positive regulation of ephrin receptor signaling pathway; positive regulation of transcription of Notch receptor target; regulation of timing of cell differentiation; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; sebaceous gland development; somatic stem cell maintenance; transcription factor complex; ventricular trabecula myocardium morphogenesis,PF09270;PF09271;,4.00E-126,CHOYP_SUH.1.1,,,,,,,SUH_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; arterial endothelial cell fate commitment [GO:0060844]; atrioventricular canal development [GO:0036302]; auditory receptor cell fate commitment [GO:0009912]; B cell differentiation [GO:0030183]; blood vessel endothelial cell fate specification [GO:0097101]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; cardiac left ventricle morphogenesis [GO:0003214]; Clara cell differentiation [GO:0060486]; defense response to bacterium [GO:0042742]; dorsal aorta morphogenesis [GO:0035912]; endocardium morphogenesis [GO:0003160]; epidermal cell fate specification [GO:0009957]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; hair follicle maturation [GO:0048820]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; labyrinthine layer blood vessel development [GO:0060716]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ossification [GO:0030279]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; pituitary gland development [GO:0021983]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:1901297]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell proliferation involved in heart morphogenesis [GO:2000138]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of ERBB signaling pathway [GO:1901186]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of timing of cell differentiation [GO:0048505]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; sebaceous gland development [GO:0048733]; secondary heart field specification [GO:0003139]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp70792_c0_seq1,208,59.1346,0.71841957,0,5,,1.00E-20,A1SHV9,Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS),Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS),GO:0005524; GO:0002161; GO:0005737; GO:0004823; GO:0006429; GO:0006450,ATP binding; aminoacyl-tRNA editing activity; cytoplasm; leucine-tRNA ligase activity; leucyl-tRNA aminoacylation; regulation of translational fidelity,PF08264;PF00133;PF13603;PF09334;,,,,,,,,,SYL_NOCSJ,Nocardioides sp. (strain ATCC BAA-499 / JS614),leucyl-tRNA aminoacylation [GO:0006429] comp70822_c0_seq1,292,41.4384,0.403586,2,19,,7.00E-46,A0MLS5,Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1),Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1),GO:0003677; GO:0032922; GO:0005737; GO:0005634; GO:0006355; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"DNA binding; circadian regulation of gene expression; cytoplasm; nucleus; regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;PF00989;,,,,,,,,,BMAL1_HORSE,Equus caballus (Horse),"circadian regulation of gene expression [GO:0032922]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; regulation of type B pancreatic cell development [GO:2000074]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp70833_c0_seq1,265,46.4151,0.28283231,3,0,,1.00E-10,Q5R1P0,"Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor 1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)","Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor 1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)",GO:0030054; GO:0005234; GO:0016021; GO:0004970; GO:0035235; GO:0014069; GO:0045211,cell junction; extracellular-glutamate-gated ion channel activity; integral to membrane; ionotropic glutamate receptor activity; ionotropic glutamate receptor signaling pathway; postsynaptic density; postsynaptic membrane,PF01094;PF10562;PF00060;PF10613;,,,,,,,,,NMDZ1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp70845_c0_seq1,254,49.2126,0.72369543,0,11,,9.00E-15,Q6AUV1,Xanthine dehydrogenase (EC 1.17.1.4),Xanthine dehydrogenase (EC 1.17.1.4),GO:0051537; GO:0008762; GO:0009055; GO:0050660; GO:0005506; GO:0004854,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; xanthine dehydrogenase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_ORYSJ,Oryza sativa subsp. japonica (Rice), comp70875_c0_seq1,290,41.7241,0.55962204,5,18,,2.00E-27,Q95LT8,Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),Tetratricopeptide repeat protein 39B (TPR repeat protein 39B),,,PF10300;PF13181;,,,,,,,,,TT39B_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp70888_c1_seq1,559,49.9106,0.17770313,12,27,,1.00E-15,Q93015,N-acetyltransferase 6 (EC 2.3.1.-) (Protein fusion-2) (Protein fus-2),N-acetyltransferase 6 (EC 2.3.1.-) (Protein fusion-2) (Protein fus-2),GO:0008080; GO:0005739,N-acetyltransferase activity; mitochondrion,PF00583;,,,,,,,,,NAT6_HUMAN,Homo sapiens (Human), comp70889_c0_seq1,581,42.685,0.53412154,7,29,,7.00E-41,Q58A42,Protein DD3-3,Protein DD3-3,GO:0016021,integral to membrane,,1.00E-18,CHOYP_BRAFLDRAFT_120072.1.1,,,,,,,DD3_DICDI,Dictyostelium discoideum (Slime mold), comp70911_c0_seq1,295,48.8136,1.13411265,6,15,,1.00E-09,O00339,Matrilin-2,Matrilin-2,GO:0007411; GO:0005604; GO:0005509; GO:0031104; GO:0008347; GO:0001764; GO:0005578; GO:0048678,axon guidance; basement membrane; calcium ion binding; dendrite regeneration; glial cell migration; neuron migration; proteinaceous extracellular matrix; response to axon injury,PF12662;PF07645;PF10393;PF00092;,,,,,,,,,MATN2_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; response to axon injury [GO:0048678] comp70932_c0_seq1,681,42.7313,0.22552959,20,8,,3.00E-96,Q1RLX4,Trafficking protein particle complex subunit 11 (Protein foie gras),Trafficking protein particle complex subunit 11 (Protein foie gras),GO:0005794; GO:0001889; GO:0060041; GO:0016192,Golgi apparatus; liver development; retina development in camera-type eye; vesicle-mediated transport,PF11817;PF12742;,2.00E-123,CHOYP_BRAFLDRAFT_87429.1.1,,,,,,,TPC11_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),liver development [GO:0001889]; retina development in camera-type eye [GO:0060041]; vesicle-mediated transport [GO:0016192] comp70934_c0_seq1,224,58.9286,0.77480883,0,9,,4.00E-30,P48629,"Omega-6 fatty acid desaturase, chloroplastic (EC 1.14.19.-)","Omega-6 fatty acid desaturase, chloroplastic (EC 1.14.19.23)",GO:0031969; GO:0016491; GO:0006636,chloroplast membrane; oxidoreductase activity; unsaturated fatty acid biosynthetic process,PF00487;,,,,,,,,,FAD6C_SPIOL,Spinacia oleracea (Spinach),unsaturated fatty acid biosynthetic process [GO:0006636] comp70944_c1_seq1,257,41.6342,0.38914616,10,0,,8.00E-07,Q9UPQ7,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0031594; GO:0007528; GO:0004842; GO:0008270,neuromuscular junction; neuromuscular junction development; ubiquitin-protein ligase activity; zinc ion binding,PF00595;,,,,,,,,,PZRN3_HUMAN,Homo sapiens (Human),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp70949_c0_seq1,394,40.6091,0.77148934,1,28,,2.00E-35,Q9Y2P5,"Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Fatty-acid-coenzyme A ligase, very long-chain 3) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase homolog 2) (VLCS-H2) (VLCSH2) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR)","Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Fatty-acid-coenzyme A ligase, very long-chain 3) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase homolog 2) (VLCS-H2) (VLCSH2) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR)",GO:0005524; GO:0009925; GO:0015721; GO:0006699; GO:0047747; GO:0015245; GO:0030176; GO:0046951; GO:0015911; GO:0043234; GO:0006642; GO:0000038; GO:0031957,ATP binding; basal plasma membrane; bile acid and bile salt transport; bile acid biosynthetic process; cholate-CoA ligase activity; fatty acid transporter activity; integral to endoplasmic reticulum membrane; ketone body biosynthetic process; plasma membrane long-chain fatty acid transport; protein complex; triglyceride mobilization; very long-chain fatty acid metabolic process; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,,,,,,,,,S27A5_HUMAN,Homo sapiens (Human),bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; ketone body biosynthetic process [GO:0046951]; plasma membrane long-chain fatty acid transport [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038] comp70949_c0_seq2,279,36.9176,0.54645511,0,4,,,,,,,,,8.00E-11,CHOYP_SLC27A2.1.1,,,,,,,,, comp70970_c0_seq1,324,44.4444,0.69016101,0,23,,3.00E-06,G3V8T1,M-phase phosphoprotein 8,M-phase phosphoprotein 8,GO:0035064; GO:0045892; GO:0005720; GO:0000788; GO:0044030; GO:0006351,"methylated histone residue binding; negative regulation of transcription, DNA-dependent; nuclear heterochromatin; nuclear nucleosome; regulation of DNA methylation; transcription, DNA-dependent",PF12796;PF00385;,,,,,,,,,MPP8_RAT,Rattus norvegicus (Rat),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of DNA methylation [GO:0044030]; transcription, DNA-templated [GO:0006351]" comp70985_c0_seq1,843,43.1791,0.71482254,25,29,,5.00E-65,Q05AQ3,Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42),GO:0015217; GO:0080122; GO:0005347; GO:0043262; GO:0015228; GO:0016021; GO:0005743; GO:0005739,ADP transmembrane transporter activity; AMP transmembrane transporter activity; ATP transmembrane transporter activity; adenosine-diphosphatase activity; coenzyme A transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; mitochondrion,PF00153;,9.00E-16,CHOYP_LOC576399.1.1,,,,,,,S2542_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412] comp71009_c0_seq1,508,46.2598,1.15818123,15,29,,2.00E-23,Q8R0M8,Monocarboxylate transporter 5 (MCT 5),Monocarboxylate transporter 5 (MCT 5),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT5_MOUSE,Mus musculus (Mouse),plasma membrane lactate transport [GO:0035879] comp71019_c0_seq1,262,48.0916,0.50027903,8,20,,4.00E-29,Q5U374,Kelch-like protein 12,Kelch-like protein 12,GO:0048208; GO:0031463; GO:0030134; GO:0016055; GO:0009952; GO:0060028; GO:0006513,COPII vesicle coating; Cul3-RING ubiquitin ligase complex; ER to Golgi transport vesicle; Wnt receptor signaling pathway; anterior/posterior pattern specification; convergent extension involved in axis elongation; protein monoubiquitination,PF07707;PF00651;PF01344;,3.00E-28,CHOYP_KLH12.1.3,,,,,,,KLH12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] comp71022_c0_seq1,774,35.1421,0.46516147,40,53,,3.00E-21,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp71067_c0_seq1,379,44.3272,0.78235839,7,4,,6.00E-15,A9ULE9,DnaJ homolog subfamily C member 22,DnaJ homolog subfamily C member 22,GO:0016021,integral to membrane,PF00226;PF05154;,,,,,,,,,DJC22_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp71089_c0_seq1,271,39.4834,0.39250174,3,9,,6.00E-10,Q28CB1,TBC1 domain family member 2B,TBC1 domain family member 2B,GO:0005097; GO:0005543; GO:0032851,Rab GTPase activator activity; phospholipid binding; positive regulation of Rab GTPase activity,PF00169;PF00566;,,,,,,,,,TBD2B_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp71091_c0_seq1,542,40.0369,0.93492054,3,54,,2.00E-10,Q0V9W6,BTB/POZ domain-containing protein 6,BTB/POZ domain-containing protein 6,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp71098_c0_seq1,519,46.2428,0.77206169,18,10,,1.00E-38,Q9VLS1,Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,2.00E-28,CHOYP_KPBB.2.2,,,,,,,KPBB_DROME,Drosophila melanogaster (Fruit fly),glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp71103_c0_seq1,206,38.835,0.6472948,5,0,,3.00E-19,Q6A051,Attractin-like protein 1,Attractin-like protein 1,GO:0007186; GO:0030246; GO:0016021; GO:0007275; GO:0005886; GO:0004872,G-protein coupled receptor signaling pathway; carbohydrate binding; integral to membrane; multicellular organismal development; plasma membrane; receptor activity,PF00431;PF07974;PF01344;PF00053;PF00059;PF01437;,1.00E-38,CHOYP_LOC100871946.1.1,,,,,,,ATRN1_MOUSE,Mus musculus (Mouse),G-protein coupled receptor signaling pathway [GO:0007186] comp71122_c0_seq1,330,39.697,0.23310073,3,26,,1.00E-23,P30793,GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I),GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I),GO:0035998; GO:0005525; GO:0006184; GO:0003934; GO:0005509; GO:0050662; GO:0031410; GO:0005829; GO:0042416; GO:0045776; GO:0050884; GO:0006809; GO:0031965; GO:0051000; GO:0043234; GO:0051291; GO:0051260; GO:0008217; GO:0014916; GO:0034341; GO:0032496; GO:0048265; GO:0034612; GO:0006729; GO:0046654; GO:0042311; GO:0008270,"7,8-dihydroneopterin 3'-triphosphate biosynthetic process; GTP binding; GTP catabolic process; GTP cyclohydrolase I activity; calcium ion binding; coenzyme binding; cytoplasmic vesicle; cytosol; dopamine biosynthetic process; negative regulation of blood pressure; neuromuscular process controlling posture; nitric oxide biosynthetic process; nuclear membrane; positive regulation of nitric-oxide synthase activity; protein complex; protein heterooligomerization; protein homooligomerization; regulation of blood pressure; regulation of lung blood pressure; response to interferon-gamma; response to lipopolysaccharide; response to pain; response to tumor necrosis factor; tetrahydrobiopterin biosynthetic process; tetrahydrofolate biosynthetic process; vasodilation; zinc ion binding",PF01227;,3.00E-11,CHOYP_GCH1.1.2,,,,,,,GCH1_HUMAN,Homo sapiens (Human),"7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]" comp71142_c0_seq1,711,48.2419,0.54275922,34,45,,7.00E-60,Q5T8I3,Protein FAM102B,Protein FAM102B,,,PF10358;,7.00E-23,CHOYP_LOC100890710.1.1,,,,,,,F102B_HUMAN,Homo sapiens (Human), comp71157_c0_seq1,356,38.2022,0.9266783,6,10,,3.00E-11,P14404,MDS1 and EVI1 complex locus protein EVI1 (Ecotropic virus integration site 1 protein) (EVI-1),MDS1 and EVI1 complex locus protein EVI1 (Ecotropic virus integration site 1 protein) (EVI-1),GO:0003677; GO:0006915; GO:0030154; GO:0035115; GO:0035116; GO:0030900; GO:0071425; GO:0001701; GO:0006954; GO:0046872; GO:0046329; GO:0043069; GO:0045892; GO:0001780; GO:0016607; GO:0060039; GO:0045944; GO:0009791; GO:0042803; GO:0051726; GO:0042127; GO:0072001; GO:0009617; GO:0003700; GO:0006351,"DNA binding; apoptotic process; cell differentiation; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; forebrain development; hematopoietic stem cell proliferation; in utero embryonic development; inflammatory response; metal ion binding; negative regulation of JNK cascade; negative regulation of programmed cell death; negative regulation of transcription, DNA-dependent; neutrophil homeostasis; nuclear speck; pericardium development; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein homodimerization activity; regulation of cell cycle; regulation of cell proliferation; renal system development; response to bacterium; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,EVI1_MOUSE,Mus musculus (Mouse),"apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; forebrain development [GO:0030900]; hematopoietic stem cell proliferation [GO:0071425]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; maintenance of cell number [GO:0098727]; negative regulation of JNK cascade [GO:0046329]; negative regulation of programmed cell death [GO:0043069]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil homeostasis [GO:0001780]; pericardium development [GO:0060039]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of cell cycle [GO:0051726]; regulation of cell proliferation [GO:0042127]; renal system development [GO:0072001]; response to bacterium [GO:0009617]; transcription, DNA-templated [GO:0006351]" comp71159_c0_seq1,430,39.7674,0.41306357,15,33,,5.00E-17,Q7TT18,Activating transcription factor 7-interacting protein 1 (ATFa-associated modulator) (mAM) (MBD1-containing chromatin-associated factor 1),Activating transcription factor 7-interacting protein 1 (ATFa-associated modulator) (mAM) (MBD1-containing chromatin-associated factor 1),GO:0016887; GO:0006306; GO:0000122; GO:0005634; GO:0045893; GO:0045898; GO:0003714; GO:0005667; GO:0006351,"ATPase activity; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription, DNA-dependent; regulation of RNA polymerase II transcriptional preinitiation complex assembly; transcription corepressor activity; transcription factor complex; transcription, DNA-dependent",PF16788;PF16794;,6.00E-27,CHOYP_LOC100881659.1.1,,,,,,,MCAF1_MOUSE,Mus musculus (Mouse),"DNA methylation [GO:0006306]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045898]; transcription, DNA-templated [GO:0006351]" comp71163_c0_seq1,569,48.5062,0.54014381,30,4,,1.00E-16,Q9JIL5,Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF07525;PF01167;,2.00E-23,CHOYP_DPSE_GA18988.1.1,,,,,,,TULP4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567] comp71173_c0_seq1,271,37.2694,0.81368629,1,15,,2.00E-15,P24399,Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2),Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN239_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp71267_c0_seq1,426,41.784,0.48572057,8,25,,2.00E-33,Q8VHK0,Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.27) (Choloyl-coenzyme A thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1),Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.27) (Choloyl-coenzyme A thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1),GO:0047617; GO:0006637; GO:0004091; GO:0033882; GO:0005777; GO:0007031,acyl-CoA hydrolase activity; acyl-CoA metabolic process; carboxylesterase activity; choloyl-CoA hydrolase activity; peroxisome; peroxisome organization,,,,,,,,,,ACOT8_RAT,Rattus norvegicus (Rat),acyl-CoA metabolic process [GO:0006637]; negative regulation of CD4 biosynthetic process [GO:0045225]; peroxisome organization [GO:0007031] comp71275_c0_seq1,311,35.6913,1.01299749,4,10,,3.00E-31,Q37370,Cytochrome c oxidase subunit 1+2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I+II),Cytochrome c oxidase subunit 1+2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I+II),GO:0009060; GO:0005507; GO:0004129; GO:0009055; GO:0022900; GO:0020037; GO:0016021; GO:0005506; GO:0005743; GO:0006119; GO:0070469,aerobic respiration; copper ion binding; cytochrome-c oxidase activity; electron carrier activity; electron transport chain; heme binding; integral to membrane; iron ion binding; mitochondrial inner membrane; oxidative phosphorylation; respiratory chain,PF00115;PF00116;PF02790;,7.00E-63,CHOYP_COX1.15.15,,,,,,,COX1_ACACA,Acanthamoeba castellanii (Amoeba),aerobic respiration [GO:0009060]; electron transport chain [GO:0022900]; oxidative phosphorylation [GO:0006119] comp71278_c0_seq1,355,40.5634,0.27661447,14,0,,1.00E-22,Q6PIJ4,Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B),Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B),GO:0003677; GO:0006310; GO:0006281; GO:0031011; GO:0005634; GO:0006355; GO:0006351,"DNA binding; DNA recombination; DNA repair; Ino80 complex; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF14465;,,,,,,,,,NFRKB_MOUSE,Mus musculus (Mouse),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp71279_c0_seq1,214,44.8598,0.28302505,1,29,,6.00E-38,Q6P886,Lariat debranching enzyme (EC 3.1.-.-),Lariat debranching enzyme (EC 3.1.-.-),GO:0008419; GO:0000375; GO:0006397; GO:0005634,"RNA lariat debranching enzyme activity; RNA splicing, via transesterification reactions; mRNA processing; nucleus",PF05011;PF00149;,4.00E-25,CHOYP_LOC577338.1.1,,,,,,,DBR1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"mRNA splicing, via spliceosome [GO:0000398]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA splicing, via transesterification reactions [GO:0000375]" comp71283_c0_seq1,311,38.9068,0.59705374,21,12,,4.00E-46,Q9D6N5,Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha),Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha),GO:0000122; GO:0005634; GO:0043565; GO:0003714; GO:0008134; GO:0006351,"negative regulation of transcription from RNA polymerase II promoter; nucleus; sequence-specific DNA binding; transcription corepressor activity; transcription factor binding; transcription, DNA-dependent",PF00808;,3.00E-30,CHOYP_NC2A.1.1,,,,,,,NC2A_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp71304_c0_seq1,383,37.5979,0.59271097,21,4,,3.00E-10,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp71306_c0_seq1,444,45.4955,0.41408399,10,25,,6.00E-70,C3YWU0,Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),GO:0004560; GO:0005576; GO:0006004,alpha-L-fucosidase activity; extracellular region; fucose metabolic process,PF01120;PF16757;,6.00E-53,CHOYP_LOC592142.7.9,,,,,,,FUCO_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),fucose metabolic process [GO:0006004] comp71322_c0_seq1,321,65.109,1.10952837,1,29,,1.00E-12,P44331,Ribokinase (EC 2.7.1.15),Ribokinase (RK) (EC 2.7.1.15),GO:0005524; GO:0019303; GO:0005737; GO:0004747,ATP binding; D-ribose catabolic process; cytoplasm; ribokinase activity,PF00294;,,,,,,,,,RBSK_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),D-ribose catabolic process [GO:0019303] comp71360_c0_seq1,577,42.6343,0.45955217,20,19,,2.00E-91,Q8CIV2,Membralin (Transmembrane protein 259),Membralin (Transmembrane protein 259),GO:0016021,integral to membrane,PF09746;,7.00E-123,CHOYP_LOC100712483.1.1,,,,,,,MBRL_MOUSE,Mus musculus (Mouse),negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976] comp71385_c0_seq1,450,40.4444,0.98221901,5,38,,4.00E-08,Q8C4V4,F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) (Protein after-hours) (Protein overtime),F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) (Protein after-hours) (Protein overtime),GO:0019005; GO:0031146; GO:0005829; GO:0043153; GO:0005654; GO:0016567; GO:0048511,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cytosol; entrainment of circadian clock by photoperiod; nucleoplasm; protein ubiquitination; rhythmic process,PF00646;,,,,,,,,,FBXL3_MOUSE,Mus musculus (Mouse),circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp71400_c0_seq1,480,45.4167,0.72879104,2,43,,2.00E-22,Q80WN8,"Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]","Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]",GO:0032580; GO:0003945; GO:0003831; GO:0016021; GO:0046872; GO:0006486,"Golgi cisterna membrane; N-acetyllactosamine synthase activity; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; integral to membrane; metal ion binding; protein glycosylation",PF02709;PF13733;,,,,,,,,,B4GT3_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),protein glycosylation [GO:0006486] comp71416_c0_seq1,565,43.3628,0.60397682,18,18,,,,,,,,,1.00E-18,CHOYP_LOC100369720.1.1,,,,,,,,, comp71427_c0_seq1,272,42.2794,0.49727448,3,31,,2.00E-28,Q9PT62,Frizzled-4 (Fz-4) (Xfz4),Frizzled-4 (Fz-4) (Xfz4),GO:0004930; GO:0016055; GO:0042813; GO:0016021; GO:0007275; GO:0005886,G-protein coupled receptor activity; Wnt receptor signaling pathway; Wnt-activated receptor activity; integral to membrane; multicellular organismal development; plasma membrane,PF01534;PF01392;,2.00E-23,CHOYP_FZD4.1.1,,,,,,,FZD4_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275] comp71432_c1_seq1,303,39.2739,0.63371744,2,6,,8.00E-21,Q03468,DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),GO:0005524; GO:0003677; GO:0008094; GO:0007256; GO:0007257; GO:0006284; GO:0003682; GO:0004386; GO:0008630; GO:0035264; GO:0005730; GO:0045494; GO:0032786; GO:0032403; GO:0006290; GO:0009411; GO:0010224; GO:0010165; GO:0010332; GO:0006979; GO:0000303; GO:0009636; GO:0008023; GO:0006366; GO:0006283,"ATP binding; DNA binding; DNA-dependent ATPase activity; activation of JNKK activity; activation of JUN kinase activity; base-excision repair; chromatin binding; helicase activity; intrinsic apoptotic signaling pathway in response to DNA damage; multicellular organism growth; nucleolus; photoreceptor cell maintenance; positive regulation of DNA-dependent transcription, elongation; protein complex binding; pyrimidine dimer repair; response to UV; response to UV-B; response to X-ray; response to gamma radiation; response to oxidative stress; response to superoxide; response to toxic substance; transcription elongation factor complex; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF00271;PF00176;,1.00E-20,CHOYP_ERCC6.1.1,,,,,,,ERCC6_HUMAN,Homo sapiens (Human),"activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]" comp71454_c0_seq1,264,56.8182,1.27564676,0,1,,1.00E-29,P0A0K7,DNA gyrase subunit B (EC 5.99.1.3),DNA gyrase subunit B (EC 5.99.1.3),GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0006261; GO:0005694; GO:0005737; GO:0000287,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; DNA-dependent DNA replication; chromosome; cytoplasm; magnesium ion binding,PF00204;PF00986;PF02518;PF01751;,,,,,,,,,GYRB_STAAW,Staphylococcus aureus (strain MW2),DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265] comp71458_c0_seq1,535,46.1682,0.47556814,9,5,,1.00E-54,Q76NQ1,Inactive rhomboid protein 1 (iRhom) (Rhomboid family protein rhomboid-5),Inactive rhomboid protein 1 (iRhom) (Rhomboid family protein rhomboid-5),GO:0005789; GO:0016021; GO:0042059; GO:0010841; GO:0015031; GO:0006508; GO:0030431,"endoplasmic reticulum membrane; integral to membrane; negative regulation of epidermal growth factor receptor signaling pathway; positive regulation of circadian sleep/wake cycle, wakefulness; protein transport; proteolysis; sleep",PF01694;,,,,,,,,,RHDF1_DROME,Drosophila melanogaster (Fruit fly),"negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of circadian sleep/wake cycle, wakefulness [GO:0010841]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of protein secretion [GO:0050708]; sleep [GO:0030431]" comp71458_c1_seq1,578,47.2318,0.47304063,22,0,,,,,,,,,8.00E-34,CHOYP_RHDF1.1.3,,,,,,,,, comp71461_c0_seq1,384,55.9896,1.13688456,0,15,,3.00E-11,P94476,Uncharacterized protein YebA,Uncharacterized protein YebA,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF13559;PF01841;,,,,,,,,,YEBA_BACSU,Bacillus subtilis (strain 168), comp71466_c1_seq1,338,45.5621,0.51888209,2,8,,3.00E-13,Q9DA37,Sphingomyelin synthase-related protein 1 (SMSr) (EC 2.7.8.-) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8),Sphingomyelin synthase-related protein 1 (SMSr) (EC 2.7.8.-) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8),GO:0046513; GO:0030176; GO:2000303; GO:0006686; GO:0016740,ceramide biosynthetic process; integral to endoplasmic reticulum membrane; regulation of ceramide biosynthetic process; sphingomyelin biosynthetic process; transferase activity,PF14360;PF00536;,,,,,,,,,SAMD8_MOUSE,Mus musculus (Mouse),ceramide biosynthetic process [GO:0046513]; regulation of ceramide biosynthetic process [GO:2000303]; sphingomyelin biosynthetic process [GO:0006686] comp71467_c0_seq1,517,41.5861,0.18262011,16,13,,1.00E-39,Q6P9U1,Nucleoside diphosphate-linked moiety X motif 22 (Nudix motif 22),Nucleoside diphosphate-linked moiety X motif 22 (Nudix motif 22),GO:0016787,hydrolase activity,,,,,,,,,,NUD22_RAT,Rattus norvegicus (Rat), comp71468_c0_seq1,431,41.5313,0.48881329,5,37,,5.00E-10,O93567,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),GO:0003677; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_CHICK,Gallus gallus (Chicken),"transcription, DNA-templated [GO:0006351]" comp71488_c0_seq1,293,60.4096,1.31721964,0,34,,2.00E-10,Q9I472,"Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Corrinoid adenosyltransferase)","Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Corrinoid adenosyltransferase)",GO:0005524; GO:0008817; GO:0009236; GO:0051188; GO:0005737; GO:0006779,"ATP binding; cob(I)yrinic acid a,c-diamide adenosyltransferase activity; cobalamin biosynthetic process; cofactor biosynthetic process; cytoplasm; porphyrin-containing compound biosynthetic process",PF12557;PF02572;,,,,,,,,,COBO_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779] comp71515_c0_seq1,559,42.0394,1.03981319,0,25,,1.00E-07,Q10131,Calexcitin-1,Calexcitin-1,GO:0005509,calcium ion binding,,,,,,,,,,CEX1_CAEEL,Caenorhabditis elegans, comp71527_c0_seq1,527,34.7249,0.94941603,4,62,,2.00E-08,Q0VD19,Sphingomyelin phosphodiesterase (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase),Sphingomyelin phosphodiesterase (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase),GO:0016798; GO:0005764; GO:0043407; GO:0035307; GO:0006685; GO:0004767; GO:0023021,"hydrolase activity, acting on glycosyl bonds; lysosome; negative regulation of MAP kinase activity; positive regulation of protein dephosphorylation; sphingomyelin catabolic process; sphingomyelin phosphodiesterase activity; termination of signal transduction",PF00149;,,,1.00E-10,ruditapes_c16504,,,,,ASM_BOVIN,Bos taurus (Bovine),ceramide biosynthetic process [GO:0046513]; negative regulation of MAP kinase activity [GO:0043407]; positive regulation of protein dephosphorylation [GO:0035307]; sphingomyelin catabolic process [GO:0006685]; termination of signal transduction [GO:0023021] comp71544_c0_seq1,615,39.8374,0.61575533,15,19,,1.00E-46,Q8AVI4,Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog),Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog),GO:0005634; GO:0046579; GO:0019903; GO:0000164,nucleus; positive regulation of Ras protein signal transduction; protein phosphatase binding; protein phosphatase type 1 complex,PF13855;,1.00E-32,CHOYP_LOC100863920.1.1,,,,,,,SHOC2_XENLA,Xenopus laevis (African clawed frog),positive regulation of Ras protein signal transduction [GO:0046579] comp71550_c0_seq1,284,39.4366,0.40042646,2,16,,4.00E-24,Q2NKQ1,Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2),Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2),GO:0005794; GO:0005097; GO:0032851,Golgi apparatus; Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF02759;,3.00E-29,CHOYP_SGSM1.1.2,,,,,,,SGSM1_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp71601_c0_seq1,244,49.1803,0.75196576,5,17,,5.00E-18,Q9D565,WD repeat-containing protein 64,WD repeat-containing protein 64,,,PF00400;,,,,,,,,,WDR64_MOUSE,Mus musculus (Mouse), comp71620_c0_seq1,346,44.5087,0.23666012,13,0,,2.00E-59,Q8K010,5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase),5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase),GO:0017168; GO:0005524; GO:0006749,5-oxoprolinase (ATP-hydrolyzing) activity; ATP binding; glutathione metabolic process,PF05378;PF01968;PF02538;,3.00E-68,CHOYP_BRAFLDRAFT_214348.1.2,,,,,,,OPLA_MOUSE,Mus musculus (Mouse),glutathione metabolic process [GO:0006749] comp71633_c0_seq1,236,41.9492,0.50212766,5,0,,,,,,,,,2.00E-30,CHOYP_MYSM1.1.1,,,,,,,,, comp71635_c0_seq1,346,49.1329,0.91265989,12,12,,1.00E-59,Q8VI36,Paxillin,Paxillin,GO:0000187; GO:0048754; GO:0005938; GO:0006928; GO:0005856; GO:0007010; GO:0005925; GO:0048041; GO:0007229; GO:0030027; GO:0030032; GO:0018108; GO:0030159; GO:0008270,activation of MAPK activity; branching morphogenesis of an epithelial tube; cell cortex; cellular component movement; cytoskeleton; cytoskeleton organization; focal adhesion; focal adhesion assembly; integrin-mediated signaling pathway; lamellipodium; lamellipodium assembly; peptidyl-tyrosine phosphorylation; receptor signaling complex scaffold activity; zinc ion binding,PF00412;,8.00E-63,CHOYP_CPIPJ_CPIJ003871.1.1,,,,,,,PAXI_MOUSE,Mus musculus (Mouse),activation of MAPK activity [GO:0000187]; branching morphogenesis of an epithelial tube [GO:0048754]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; growth hormone receptor signaling pathway [GO:0060396]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp71667_c0_seq1,472,48.5169,0.68613837,23,16,,9.00E-52,Q95JN5,Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1) (Fragment),Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1) (Fragment),GO:0005524; GO:0006200; GO:0016887; GO:0006812; GO:0016021; GO:0046872,ATP binding; ATP catabolic process; ATPase activity; cation transport; integral to membrane; metal ion binding,PF00690;PF00122;PF12409;,2.00E-34,CHOYP_LOC582670.1.1,,,,,,,AT133_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),cation transport [GO:0006812] comp71707_c0_seq1,335,50.1493,0.57273238,8,0,,1.00E-52,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-58,CHOYP_LOC577371.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp71738_c0_seq1,384,40.1042,0.47247866,1,29,,2.00E-44,Q9VVE5,RNA-binding protein Musashi homolog Rbp6,RNA-binding protein Musashi homolog Rbp6,GO:0005737; GO:0000166; GO:0008266; GO:0005844; GO:0048864,cytoplasm; nucleotide binding; poly(U) RNA binding; polysome; stem cell development,PF00076;,6.00E-52,CHOYP_RBP6.2.2,,,,,,,MSIR6_DROME,Drosophila melanogaster (Fruit fly),stem cell development [GO:0048864] comp71747_c0_seq1,289,44.9827,0.41193675,2,15,,4.00E-22,Q27J81,Inverted formin-2 (HBEBP2-binding protein C),Inverted formin-2 (HBEBP2-binding protein C),GO:0030036; GO:0005783; GO:0005634; GO:0048471; GO:0090140,actin cytoskeleton organization; endoplasmic reticulum; nucleus; perinuclear region of cytoplasm; regulation of mitochondrial fission,PF06367;PF06371;PF02181;PF02205;,4.00E-15,CHOYP_INF2.3.5,,,,,,,INF2_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; regulation of mitochondrial fission [GO:0090140] comp71763_c0_seq1,394,42.132,0.46037593,19,30,,4.00E-18,P18433,Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),GO:0007411; GO:0008286; GO:0005887; GO:0006468; GO:0005001,axon guidance; insulin receptor signaling pathway; integral to plasma membrane; protein phosphorylation; transmembrane receptor protein tyrosine phosphatase activity,PF00102;,,,,,,,,,PTPRA_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165] comp71769_c0_seq1,439,41.9134,0.64327819,4,29,,3.00E-28,Q8CD19,LanC-like protein 3,LanC-like protein 3,GO:0003824; GO:0008152,catalytic activity; metabolic process,PF05147;,,,,,,,,,LANC3_MOUSE,Mus musculus (Mouse), comp71771_c0_seq1,326,46.6258,0.9666236,1,23,,2.00E-07,O48882,1-aminocyclopropane-1-carboxylate oxidase 2 (ACC oxidase 2) (EC 1.14.17.4) (Ethylene-forming enzyme) (EFE),1-aminocyclopropane-1-carboxylate oxidase 2 (ACC oxidase 2) (EC 1.14.17.4) (Ethylene-forming enzyme) (EFE),GO:0009815; GO:0031418; GO:0009693; GO:0009835; GO:0046872; GO:0016706,"1-aminocyclopropane-1-carboxylate oxidase activity; L-ascorbic acid binding; ethylene biosynthetic process; fruit ripening; metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF03171;PF14226;,,,3.00E-15,ruditapes_c20326,,,,,ACCO2_MALDO,Malus domestica (Apple) (Pyrus malus),ethylene biosynthetic process [GO:0009693]; fruit ripening [GO:0009835] comp71776_c0_seq1,202,45.0495,0.58898929,2,9,,7.00E-16,Q9VYA0,Probable glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]),Probable glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]),GO:0005524; GO:0009435; GO:0003952; GO:0016810,"ATP binding; NAD biosynthetic process; NAD+ synthase (glutamine-hydrolyzing) activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",PF00795;PF02540;,,,,,,,,,NADE_DROME,Drosophila melanogaster (Fruit fly),NAD biosynthetic process [GO:0009435] comp71802_c0_seq1,242,41.7355,0.382082,3,7,,2.00E-14,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp71805_c0_seq1,503,37.7734,0.63000249,8,33,,2.00E-08,Q9TU23,Centrosomal protein of 290 kDa (Cep290) (Nephrocystin-6) (Fragment),Centrosomal protein of 290 kDa (Cep290) (Nephrocystin-6) (Fragment),GO:0036038; GO:0005813; GO:0060271; GO:0005829; GO:0005932; GO:0005634; GO:0032391; GO:0045893; GO:0015031,"TCTN-B9D complex; centrosome; cilium morphogenesis; cytosol; microtubule basal body; nucleus; photoreceptor connecting cilium; positive regulation of transcription, DNA-dependent; protein transport",PF16574;,4.00E-18,CHOYP_NEMVEDRAFT_V1G246279.1.1,,,,,,,CE290_BOVIN,Bos taurus (Bovine),"cilium morphogenesis [GO:0060271]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; protein transport [GO:0015031]" comp7180_c0_seq1,375,38.6667,0.58980812,11,0,,3.00E-22,Q5F3F2,"Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)","Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)",GO:0003677; GO:0003682; GO:0006338; GO:0042393; GO:0046872; GO:0008237; GO:0035522; GO:0005634; GO:0045944; GO:0006508; GO:0003713; GO:0006351; GO:0004221; GO:0004843,"DNA binding; chromatin binding; chromatin remodeling; histone binding; metal ion binding; metallopeptidase activity; monoubiquitinated histone H2A deubiquitination; nucleus; positive regulation of transcription from RNA polymerase II promoter; proteolysis; transcription coactivator activity; transcription, DNA-dependent; ubiquitin thiolesterase activity; ubiquitin-specific protease activity",PF01398;PF00249;PF04433;,,,,,,,,,MYSM1_CHICK,Gallus gallus (Chicken),"chromatin remodeling [GO:0006338]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp71845_c0_seq1,702,46.8661,0.26618759,36,30,,9.00E-25,Q99558,Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK),Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK),GO:0005524; GO:0007249; GO:0004709; GO:0000165; GO:0004704; GO:0031295; GO:0000186; GO:0071260; GO:0005829; GO:0006955; GO:0005634; GO:0043123,ATP binding; I-kappaB kinase/NF-kappaB cascade; MAP kinase kinase kinase activity; MAPK cascade; NF-kappaB-inducing kinase activity; T cell costimulation; activation of MAPKK activity; cellular response to mechanical stimulus; cytosol; immune response; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade,PF00069;,4.00E-13,CHOYP_BRAFLDRAFT_84620.1.1,,,,,,,M3K14_HUMAN,Homo sapiens (Human),cellular response to mechanical stimulus [GO:0071260]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209] comp71857_c0_seq1,277,47.6534,0.77223229,10,12,,,,,,,,,,,2.00E-15,ruditapes_c7243,,,,,,, comp71874_c0_seq1,460,42.3913,0.72897245,11,8,,3.00E-37,Q8AXV1,Endophilin-A1 (Endophilin-1) (SH3 domain-containing GRB2-like protein 1) (SH3p4),Endophilin-A1 (Endophilin-1) (SH3 domain-containing GRB2-like protein 1) (SH3p4),GO:0005737; GO:0008289; GO:0016020; GO:0002090; GO:0048488,cytoplasm; lipid binding; membrane; regulation of receptor internalization; synaptic vesicle endocytosis,PF03114;PF00018;,,,,,,,,,SH3G2_CHICK,Gallus gallus (Chicken),regulation of receptor internalization [GO:0002090]; synaptic vesicle endocytosis [GO:0048488] comp71874_c1_seq1,295,41.3559,0.32698525,11,11,,,,,,,,,1.00E-46,CHOYP_ISCW_ISCW008555.1.1,,,,,,,,, comp71887_c0_seq1,292,66.0959,0.88102408,0,12,,1.00E-38,O48557,60S ribosomal protein L17,60S ribosomal protein L17,GO:0015934; GO:0003735; GO:0006412,large ribosomal subunit; structural constituent of ribosome; translation,PF00237;,,,,,,,,,RL17_MAIZE,Zea mays (Maize),translation [GO:0006412] comp71891_c1_seq1,242,40.9091,1.09371753,4,8,,3.00E-23,Q03206,Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1),Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1),GO:0005525; GO:0003924; GO:0006915; GO:0048846; GO:0031103; GO:0010171; GO:0009986; GO:0031410; GO:0005829; GO:0033563; GO:0043652; GO:0016021; GO:0009898; GO:0008045; GO:0002119; GO:0001764; GO:0030334; GO:0050764; GO:0007264,GTP binding; GTPase activity; apoptotic process; axon extension involved in axon guidance; axon regeneration; body morphogenesis; cell surface; cytoplasmic vesicle; cytosol; dorsal/ventral axon guidance; engulfment of apoptotic cell; integral to membrane; internal side of plasma membrane; motor neuron axon guidance; nematode larval development; neuron migration; regulation of cell migration; regulation of phagocytosis; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAC1_CAEEL,Caenorhabditis elegans,"apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; engulfment of apoptotic cell [GO:0043652]; gastrulation [GO:0007369]; motor neuron axon guidance [GO:0008045]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264]" comp71914_c0_seq1,231,37.6623,0.98411176,0,17,,3.00E-08,Q9UK13,Zinc finger protein 221,Zinc finger protein 221,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN221_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp71930_c1_seq1,242,48.7603,0.82885136,4,8,,2.00E-19,O94925,"Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase)","Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase)",GO:0007610; GO:0034641; GO:0005829; GO:0006537; GO:0014047; GO:0004359; GO:0006543; GO:0005759; GO:0007269; GO:0051289; GO:0002087,behavior; cellular nitrogen compound metabolic process; cytosol; glutamate biosynthetic process; glutamate secretion; glutaminase activity; glutamine catabolic process; mitochondrial matrix; neurotransmitter secretion; protein homotetramerization; regulation of respiratory gaseous exchange by neurological system process,PF12796;PF04960;,,,,,,,,,GLSK_HUMAN,Homo sapiens (Human),cellular amino acid biosynthetic process [GO:0008652]; chemical synaptic transmission [GO:0007268]; glutamate biosynthetic process [GO:0006537]; glutamate secretion [GO:0014047]; glutamine catabolic process [GO:0006543]; protein homotetramerization [GO:0051289]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; suckling behavior [GO:0001967] comp72017_c1_seq1,797,46.5496,0.71904543,27,13,,,,,,,,,5.00E-32,CHOYP_DWIL_GK20806.1.1,,,,,,,,, comp72074_c0_seq1,530,42.8302,0.34324621,20,20,,1.00E-60,Q7L273,BTB/POZ domain-containing protein KCTD9,BTB/POZ domain-containing protein KCTD9,GO:0051260,protein homooligomerization,PF02214;PF11834;PF00805;,1.00E-75,CHOYP_BRAFLDRAFT_57239.1.1,,,,,,,KCTD9_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260] comp72084_c0_seq1,355,45.6338,0.43467988,2,39,,3.00E-10,Q9HC78,Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288),Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288),GO:0003677; GO:0001078; GO:0046872; GO:0005634,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; metal ion binding; nucleus,PF00651;PF00096;,,,,,,,,,ZBT20_HUMAN,Homo sapiens (Human),"positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; transcription, DNA-templated [GO:0006351]" comp72114_c1_seq1,839,38.7366,0.34992097,18,56,,1.00E-21,Q5R454,ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Protein TBX2),ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Protein TBX2),GO:0005784; GO:0006613; GO:0005829; GO:0016021,Sec61 translocon complex; cotranslational protein targeting to membrane; cytosol; integral to membrane,,,,,,,,,,AR6P1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),apoptotic process [GO:0006915]; cotranslational protein targeting to membrane [GO:0006613]; endoplasmic reticulum tubular network assembly [GO:0071787]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of L-glutamate transport [GO:0002038] comp72123_c0_seq1,241,60.9959,0.99889149,0,7,,5.00E-38,Q6A830,Lipoprotein LpqB,Lipoprotein LpqB,GO:0005886,plasma membrane,PF10646;PF10647;,,,,,,,,,LPQB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp72148_c0_seq1,298,45.6376,0.91799279,9,16,,6.00E-07,P12822,"Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]","Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]",GO:0004180; GO:0005576; GO:0016021; GO:0046872; GO:0008237; GO:0008241; GO:0005886; GO:0006508,carboxypeptidase activity; extracellular region; integral to membrane; metal ion binding; metallopeptidase activity; peptidyl-dipeptidase activity; plasma membrane; proteolysis,PF01401;,,,,,,,,,ACE_RABIT,Oryctolagus cuniculus (Rabbit), comp72180_c0_seq1,640,43.9062,0.37872044,22,11,,4.00E-09,O88509,DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB),DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB),GO:0003886; GO:0003677; GO:0043045; GO:0071230; GO:0000775; GO:0046872; GO:0006346; GO:0000122; GO:0005720; GO:0031503; GO:0006349,"DNA (cytosine-5-)-methyltransferase activity; DNA binding; DNA methylation involved in embryo development; cellular response to amino acid stimulus; chromosome, centromeric region; metal ion binding; methylation-dependent chromatin silencing; negative regulation of transcription from RNA polymerase II promoter; nuclear heterochromatin; protein complex localization; regulation of gene expression by genetic imprinting",PF00145;PF00855;,,,,,,,,,DNM3B_MOUSE,Mus musculus (Mouse),"cellular response to amino acid stimulus [GO:0071230]; chromatin silencing at rDNA [GO:0000183]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; inactivation of X chromosome by DNA methylation [GO:0060821]; methylation-dependent chromatin silencing [GO:0006346]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; protein complex localization [GO:0031503]; regulation of gene expression by genetic imprinting [GO:0006349]" comp72180_c1_seq1,308,45.4545,0.56860137,11,10,,4.00E-11,Q9Y6K1,DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA),DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA),GO:0003886; GO:0051718; GO:0003677; GO:0043045; GO:0043046; GO:0010424; GO:0046498; GO:0046499; GO:0071230; GO:0003682; GO:0000775; GO:0005737; GO:0000791; GO:0044027; GO:0046872; GO:0006346; GO:0000122; GO:0005720; GO:0016363; GO:0006349; GO:0007283; GO:0045322,"DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; DNA binding; DNA methylation involved in embryo development; DNA methylation involved in gamete generation; DNA methylation on cytosine within a CG sequence; S-adenosylhomocysteine metabolic process; S-adenosylmethioninamine metabolic process; cellular response to amino acid stimulus; chromatin binding; chromosome, centromeric region; cytoplasm; euchromatin; hypermethylation of CpG island; metal ion binding; methylation-dependent chromatin silencing; negative regulation of transcription from RNA polymerase II promoter; nuclear heterochromatin; nuclear matrix; regulation of gene expression by genetic imprinting; spermatogenesis; unmethylated CpG binding",PF00145;PF00855;,,,,,,,,,DNM3A_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; DNA methylation on cytosine within a CG sequence [GO:0010424]; hepatocyte apoptotic process [GO:0097284]; hypermethylation of CpG island [GO:0044027]; methylation-dependent chromatin silencing [GO:0006346]; mitotic cell cycle [GO:0000278]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; regulation of gene expression by genetic imprinting [GO:0006349]; response to antidepressant [GO:0036276]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; spermatogenesis [GO:0007283]" comp72193_c0_seq1,253,37.1542,0.34558363,0,47,,1.00E-30,Q9BRR0,Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47),Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47),GO:0006914; GO:0003682; GO:0005737; GO:0007040; GO:0046872; GO:0010507; GO:2000773; GO:0045892; GO:0005634; GO:0045893; GO:0043565; GO:0003700; GO:0006351,"autophagy; chromatin binding; cytoplasm; lysosome organization; metal ion binding; negative regulation of autophagy; negative regulation of cellular senescence; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of transcription, DNA-dependent; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF02023;PF00096;,,,,,,,,,ZKSC3_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; negative regulation of cellular senescence [GO:2000773]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp72227_c0_seq1,212,60.3774,0.88426876,0,8,,2.00E-35,Q6A7W0,Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS),Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS),GO:0005524; GO:0003723; GO:0005737; GO:0004831; GO:0006437,ATP binding; RNA binding; cytoplasm; tyrosine-tRNA ligase activity; tyrosyl-tRNA aminoacylation,PF00579;,,,,,,,,,SYY_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),tyrosyl-tRNA aminoacylation [GO:0006437] comp72231_c0_seq1,266,47.3684,0.40373554,3,9,,1.00E-15,Q15477,Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP),Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP),GO:0005524; GO:0004004; GO:0003723; GO:0055087; GO:0005634,ATP binding; ATP-dependent RNA helicase activity; RNA binding; Ski complex; nucleus,PF00270;PF08148;PF00271;PF13234;,,,,,,,,,SKIV2_HUMAN,Homo sapiens (Human),RNA catabolic process [GO:0006401] comp72242_c1_seq1,225,58.2222,1.21224409,0,5,,8.00E-16,P21638,Precorrin-8X methylmutase (EC 5.4.1.2) (HBA synthase) (Precorrin isomerase),Precorrin-8X methylmutase (EC 5.4.99.61) (HBA synthase) (Precorrin isomerase),GO:0009236; GO:0016993,cobalamin biosynthetic process; precorrin-8X methylmutase activity,PF02570;,,,,,,,,,COBH_PSEDE,Pseudomonas denitrificans,cobalamin biosynthetic process [GO:0009236] comp72245_c0_seq1,254,38.9764,0.42359461,3,12,,4.00E-08,P17030,Zinc finger protein 25 (Zinc finger protein KOX19),Zinc finger protein 25 (Zinc finger protein KOX19),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF25_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp7224_c0_seq1,256,58.9844,0.95186638,2,4,,5.00E-22,P58655,Phosphate transport system permease protein PstA,Phosphate transport system permease protein PstA,GO:0005315; GO:0005887; GO:0035435,inorganic phosphate transmembrane transporter activity; integral to plasma membrane; phosphate ion transmembrane transport,PF00528;,,,,,,,,,PSTA_YERPE,Yersinia pestis, comp72259_c1_seq1,205,47.8049,0.90353027,2,14,,5.00E-15,P51906,Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1),Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1),GO:0070779; GO:0051938; GO:0016595; GO:0015501; GO:0016021; GO:0005886; GO:0051260; GO:0017153,D-aspartate import; L-glutamate import; glutamate binding; glutamate:sodium symporter activity; integral to membrane; plasma membrane; protein homooligomerization; sodium:dicarboxylate symporter activity,PF00375;,,,3.00E-18,ruditapes_c22391,,,,,EAA3_MOUSE,Mus musculus (Mouse),cysteine transport [GO:0042883]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260] comp72260_c0_seq1,364,48.9011,0.55640664,8,6,,,,,,,,,3.00E-11,CHOYP_BRAFLDRAFT_124709.1.1,,,,,,,,, comp72266_c0_seq1,216,46.7593,0.42886295,1,0,,4.00E-17,Q8BX17,Gem-associated protein 5 (Gemin5),Gem-associated protein 5 (Gemin5),GO:0008380; GO:0005737; GO:0006397; GO:0017069; GO:0005681,RNA splicing; cytoplasm; mRNA processing; snRNA binding; spliceosomal complex,PF12894;PF00400;,,,,,,,,,GEMI5_MOUSE,Mus musculus (Mouse),spliceosomal snRNP assembly [GO:0000387] comp72306_c0_seq1,1037,39.6336,0.75399586,50,35,,1.00E-41,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp72334_c0_seq1,359,40.1114,1.25606712,5,37,,,,,,,,,,,1.00E-20,ruditapes_c29520,,,,,,, comp72337_c0_seq1,500,40.6,0.29874896,12,41,,3.00E-23,P24942,Excitatory amino acid transporter 1 (Glial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3),Excitatory amino acid transporter 1 (Glial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3),GO:0016323; GO:0043197; GO:0005314; GO:0016021; GO:0043490; GO:0005743; GO:0006836; GO:0010035; GO:0017153; GO:0045202,basolateral plasma membrane; dendritic spine; high-affinity glutamate transmembrane transporter activity; integral to membrane; malate-aspartate shuttle; mitochondrial inner membrane; neurotransmitter transport; response to inorganic substance; sodium:dicarboxylate symporter activity; synapse,PF00375;,1.00E-18,CHOYP_TBB4B.3.7,,,,,,,EAA1_RAT,Rattus norvegicus (Rat),L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; neurotransmitter transport [GO:0006836]; response to inorganic substance [GO:0010035] comp72349_c0_seq1,275,47.6364,0.81177544,7,0,,9.00E-31,O75081,Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4),Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4),GO:0000139; GO:0008283; GO:0003682; GO:0030851; GO:0046872; GO:0005730; GO:0005654; GO:0045944; GO:0003700; GO:0006351,"Golgi membrane; cell proliferation; chromatin binding; granulocyte differentiation; metal ion binding; nucleolus; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF08788;PF07531;PF01753;,1.00E-26,CHOYP_LOC100375491.1.1,,,,,,,MTG16_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; granulocyte differentiation [GO:0030851]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glycolytic process [GO:0045820]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp72351_c0_seq1,279,49.4624,0.53651956,7,0,,3.00E-35,P51464,Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase),Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase),GO:0042450; GO:0004056; GO:0000050,arginine biosynthetic process via ornithine; argininosuccinate lyase activity; urea cycle,PF14698;PF00206;,,,,,,,,,ARLY_LITCT,Lithobates catesbeiana (American bullfrog) (Rana catesbeiana),arginine biosynthetic process via ornithine [GO:0042450]; urea cycle [GO:0000050] comp72399_c0_seq1,217,60.8295,1.1606728,0,9,,2.00E-11,P21335,tRNA-specific adenosine deaminase (EC 3.5.4.33),tRNA-specific adenosine deaminase (EC 3.5.4.33),GO:0016787; GO:0008033; GO:0008270,hydrolase activity; tRNA processing; zinc ion binding,PF14437;,,,,,,,,,TADA_BACSU,Bacillus subtilis (strain 168),tRNA wobble adenosine to inosine editing [GO:0002100] comp72413_c0_seq1,223,42.1525,0.72594052,0,26,,6.00E-27,Q8WWF8,Calcyphosin-like protein,Calcyphosin-like protein,GO:0005509; GO:0005737,calcium ion binding; cytoplasm,PF13499;,,,,,,,,,CAPSL_HUMAN,Homo sapiens (Human), comp72442_c0_seq1,315,39.0476,0.25552818,16,14,,,,,,,,,2.00E-13,CHOYP_GBB.2.2,,,,,,,,, comp72443_c0_seq1,453,38.4106,0.65988694,32,12,,4.00E-45,Q8WXG6,MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor),MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor),GO:0017112; GO:0000187; GO:0007166; GO:0005737; GO:0005123; GO:0097194; GO:0016021; GO:0005886; GO:0030295; GO:0032483; GO:0051726; GO:1902041,Rab guanyl-nucleotide exchange factor activity; activation of MAPK activity; cell surface receptor signaling pathway; cytoplasm; death receptor binding; execution phase of apoptosis; integral to membrane; plasma membrane; protein kinase activator activity; regulation of Rab protein signal transduction; regulation of cell cycle; regulation of extrinsic apoptotic signaling pathway via death domain receptors,PF02141;PF03456;,4.00E-43,CHOYP_MADD.1.3,,,,,,,MADD_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803] comp72457_c1_seq1,285,35.0877,0.45925897,1,3,,2.00E-21,Q8R2M0,Transcription elongation factor A N-terminal and central domain-containing protein 2,Transcription elongation factor A N-terminal and central domain-containing protein 2,GO:0003677; GO:0005634; GO:0006351,"DNA binding; nucleus; transcription, DNA-dependent",PF08711;,3.00E-16,CHOYP_TEAN2.1.1,,,,,,,TEAN2_MOUSE,Mus musculus (Mouse),"transcription, DNA-templated [GO:0006351]" comp72472_c0_seq1,263,42.5856,0.42213594,9,3,,3.00E-09,Q6NYU2,Probable helicase with zinc finger domain (EC 3.6.4.-),Probable helicase with zinc finger domain (EC 3.6.4.-),GO:0005524; GO:0004386; GO:0046872; GO:0005634; GO:0003700,ATP binding; helicase activity; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity,PF00642;,2.00E-18,CHOYP_HELZ.2.2,,,,,,,HELZ_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp72479_c0_seq1,511,42.4658,0.47923941,13,23,,2.00E-55,Q7ZW24,"GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)","GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)",GO:0004377; GO:0009058; GO:0016021,"GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity; biosynthetic process; integral to membrane",PF15924;PF00534;,1.00E-17,CHOYP_ALG11.1.1,,,,,,,ALG11_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp72494_c0_seq1,328,42.6829,0.73872905,5,8,,3.00E-20,Q53HC5,Kelch-like protein 26,Kelch-like protein 26,,,PF07707;PF00651;PF01344;,8.00E-75,CHOYP_BRAFLDRAFT_223623.1.1,,,,,,,KLH26_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp72494_c1_seq1,327,46.789,0.75980753,4,22,,2.00E-10,Q5U374,Kelch-like protein 12,Kelch-like protein 12,GO:0048208; GO:0031463; GO:0030134; GO:0016055; GO:0009952; GO:0060028; GO:0006513,COPII vesicle coating; Cul3-RING ubiquitin ligase complex; ER to Golgi transport vesicle; Wnt receptor signaling pathway; anterior/posterior pattern specification; convergent extension involved in axis elongation; protein monoubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] comp72529_c0_seq1,443,42.2122,0.66713239,0,0,,4.00E-25,P00529,Tyrosine-protein kinase transforming protein ros (EC 2.7.10.1),Tyrosine-protein kinase transforming protein ros (EC 2.7.10.1),GO:0005524; GO:0016020; GO:0018108; GO:0004714; GO:0007169,ATP binding; membrane; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;,1.00E-73,CHOYP_SRC1.1.1,,,,,,,ROS_AVISU,UR2 sarcoma virus (UR2SV) (Avian sarcoma virus (strain UR2)),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp72529_c0_seq2,570,37.8947,0.54414098,2,26,,5.00E-25,Q9DE49,Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor),Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor),GO:0005524; GO:0006935; GO:0016021; GO:0007275; GO:0018108; GO:0005886; GO:0005018; GO:0035790,ATP binding; chemotaxis; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; plasma membrane; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor receptor-alpha signaling pathway,PF07679;PF07714;,,,,,,,,,PGFRA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cerebellum vasculature development [GO:0061300]; chemotaxis [GO:0006935]; embryonic cranial skeleton morphogenesis [GO:0048701]; palate development [GO:0060021] comp72529_c0_seq3,416,41.5865,0.61903192,0,0,,6.00E-46,Q02977,Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2) (Yes-related kinase) (p60-Yrk),Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2) (Yes-related kinase) (p60-Yrk),GO:0005524; GO:0004715; GO:0018108,ATP binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF07714;PF00017;PF00018;,1.00E-73,CHOYP_SRC1.1.1,,,,,,,YRK_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; cell migration [GO:0016477]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp72562_c0_seq1,352,42.3295,0.44862381,3,7,,9.00E-17,Q9EPR5,VPS10 domain-containing receptor SorCS2,VPS10 domain-containing receptor SorCS2,GO:0016021,integral to membrane,PF00801;PF15902;PF15901;,,,,,,,,,SORC2_MOUSE,Mus musculus (Mouse), comp72582_c0_seq1,361,46.5374,0.62128623,10,13,,1.00E-44,O75096,Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),GO:0016055; GO:0005509; GO:0030154; GO:0009953; GO:0042733; GO:0006897; GO:0030198; GO:0001942; GO:0016021; GO:0001822; GO:0090090; GO:0030279; GO:0042475; GO:0005886; GO:0009954; GO:0043113; GO:0001932; GO:0051124,Wnt receptor signaling pathway; calcium ion binding; cell differentiation; dorsal/ventral pattern formation; embryonic digit morphogenesis; endocytosis; extracellular matrix organization; hair follicle development; integral to membrane; kidney development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of ossification; odontogenesis of dentin-containing tooth; plasma membrane; proximal/distal pattern formation; receptor clustering; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF12662;PF00057;PF00058;,1.00E-16,CHOYP_LRP4.5.5,,,,,,,LRP4_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] comp72595_c0_seq1,525,45.1429,0.58696835,16,17,,3.00E-14,Q5JSH3,WD repeat-containing protein 44 (Rabphilin-11),WD repeat-containing protein 44 (Rabphilin-11),GO:0005794; GO:0005829; GO:0010008; GO:0048471,Golgi apparatus; cytosol; endosome membrane; perinuclear region of cytoplasm,PF00400;,,,,,,,,,WDR44_HUMAN,Homo sapiens (Human),regulation of cell migration [GO:0030334] comp72614_c0_seq1,541,44.3623,0.79179401,9,15,,4.00E-40,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,,,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp72619_c0_seq1,349,36.9628,0.67308245,8,15,,3.00E-37,Q2KIF8,"Cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)","Cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)",GO:0005524; GO:0004817; GO:0006423; GO:0005829; GO:0046872; GO:0005759,ATP binding; cysteine-tRNA ligase activity; cysteinyl-tRNA aminoacylation; cytosol; metal ion binding; mitochondrial matrix,PF01406;,,,,,,,,,SYCM_BOVIN,Bos taurus (Bovine),cysteinyl-tRNA aminoacylation [GO:0006423] comp72662_c0_seq1,616,50,0.47027563,0,0,,,,,,,,,4.00E-32,CHOYP_LOC100643070.1.1,,,,,,,,, comp72674_c1_seq1,398,43.7186,0.79073032,6,18,,2.00E-20,Q6IE52,Murinoglobulin-2,Murinoglobulin-2,GO:0005615; GO:0010951; GO:0004867,extracellular space; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,MUG2_RAT,Rattus norvegicus (Rat), comp72682_c0_seq1,301,43.5216,0.14381111,5,6,,6.00E-35,Q07175,Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase),Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase),GO:0005789; GO:0008488; GO:0016021; GO:0017187,endoplasmic reticulum membrane; gamma-glutamyl carboxylase activity; integral to membrane; peptidyl-glutamic acid carboxylation,PF05090;,,,,,,,,,VKGC_BOVIN,Bos taurus (Bovine),peptidyl-glutamic acid carboxylation [GO:0017187] comp72685_c0_seq1,318,46.2264,0.66058635,7,9,,2.00E-08,P51841,"Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)","Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)",GO:0005524; GO:0005525; GO:0004383; GO:0005887; GO:0035556; GO:0005640; GO:0097381; GO:0004672; GO:0004872; GO:0007168; GO:0022400; GO:0016056; GO:0007601,ATP binding; GTP binding; guanylate cyclase activity; integral to plasma membrane; intracellular signal transduction; nuclear outer membrane; photoreceptor disc membrane; protein kinase activity; receptor activity; receptor guanylyl cyclase signaling pathway; regulation of rhodopsin mediated signaling pathway; rhodopsin mediated signaling pathway; visual perception,PF01094;PF00211;PF07701;PF07714;,,,,,,,,,GUC2F_HUMAN,Homo sapiens (Human),detection of light stimulus involved in visual perception [GO:0050908]; intracellular signal transduction [GO:0035556]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; visual perception [GO:0007601] comp72687_c0_seq1,456,41.886,0.55157167,19,25,,1.00E-59,Q3U487,E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),GO:0005634; GO:0048471; GO:0043161; GO:0042787; GO:0004842,nucleus; perinuclear region of cytoplasm; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF03256;PF00632;,5.00E-54,CHOYP_BRAFLDRAFT_276868.1.1,,,,,,,HECD3_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp72747_c1_seq1,266,41.7293,0.34902454,7,0,,1.00E-10,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp72748_c0_seq1,217,50.2304,1.07542805,0,5,,1.00E-07,B8D0W1,Alanine racemase (EC 5.1.1.1),Alanine racemase (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR_HALOH,Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562),D-alanine biosynthetic process [GO:0030632] comp72755_c0_seq1,290,43.4483,0.378123,4,10,,,,,,,,,3.00E-22,CHOYP_NEMVEDRAFT_V1G240929.1.1,,,,,,,,, comp72756_c0_seq1,614,42.5081,0.76158947,16,6,,4.00E-74,P51905,Sodium-dependent serotonin transporter (5HT transporter) (5HTT) (Cocaine-sensitive serotonin transporter) (dSERT1),Sodium-dependent serotonin transporter (5HT transporter) (5HTT) (Cocaine-sensitive serotonin transporter) (dSERT1),GO:0043679; GO:0005261; GO:0016021; GO:0005328; GO:0006909; GO:0015222; GO:0051610,axon terminus; cation channel activity; integral to membrane; neurotransmitter:sodium symporter activity; phagocytosis; serotonin transmembrane transporter activity; serotonin uptake,PF00209;,,,,,,,,,SC6A4_DROME,Drosophila melanogaster (Fruit fly),chemical synaptic transmission [GO:0007268]; monoamine transport [GO:0015844]; phagocytosis [GO:0006909]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610] comp72762_c0_seq1,323,44.2724,0.13810874,2,12,,2.00E-09,Q9Y6Y0,Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3),Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3),GO:0008380; GO:0005737; GO:0005856; GO:0019048; GO:0043066; GO:0005654; GO:0009615; GO:0005681; GO:0005667; GO:0006383,RNA splicing; cytoplasm; cytoskeleton; modulation by virus of host morphology or physiology; negative regulation of apoptotic process; nucleoplasm; response to virus; spliceosomal complex; transcription factor complex; transcription from RNA polymerase III promoter,PF07707;PF00651;PF01344;,4.00E-34,CHOYP_LOC100372040.1.1,,,,,,,NS1BP_HUMAN,Homo sapiens (Human),negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; response to virus [GO:0009615]; RNA splicing [GO:0008380]; transcription from RNA polymerase III promoter [GO:0006383]; viral process [GO:0016032] comp72814_c0_seq1,729,38.6831,1.23412117,12,45,,1.00E-32,P29617,Homeobox protein prospero,Homeobox protein prospero,GO:0003677; GO:0007465; GO:0001078; GO:0045179; GO:0008356; GO:0055060; GO:0007411; GO:0060385; GO:0045180; GO:0007420; GO:0001708; GO:0042676; GO:0070983; GO:0007402; GO:0010001; GO:0008049; GO:0005875; GO:0050771; GO:0007406; GO:0007400; GO:0005634; GO:0007422; GO:0006909; GO:0005886; GO:0010628; GO:0008104; GO:0045676; GO:1900180; GO:0042673; GO:0050909; GO:0007416; GO:0007419,DNA binding; R7 cell fate commitment; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; apical cortex; asymmetric cell division; asymmetric neuroblast division resulting in ganglion mother cell formation; axon guidance; axonogenesis involved in innervation; basal cortex; brain development; cell fate specification; compound eye cone cell fate commitment; dendrite guidance; ganglion mother cell fate determination; glial cell differentiation; male courtship behavior; microtubule associated complex; negative regulation of axonogenesis; negative regulation of neuroblast proliferation; neuroblast fate determination; nucleus; peripheral nervous system development; phagocytosis; plasma membrane; positive regulation of gene expression; protein localization; regulation of R7 cell differentiation; regulation of protein localization to nucleus; regulation of retinal cone cell fate specification; sensory perception of taste; synapse assembly; ventral cord development,PF05044;,2.00E-42,CHOYP_ISCW_ISCW008733.1.1,,,,,,,PROS_DROME,Drosophila melanogaster (Fruit fly),"asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; compound eye cone cell fate commitment [GO:0042676]; courtship behavior [GO:0007619]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; eye photoreceptor cell differentiation [GO:0001754]; G1 to G0 transition [GO:0070314]; ganglion mother cell fate determination [GO:0007402]; glial cell differentiation [GO:0010001]; male courtship behavior [GO:0008049]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; R7 cell fate commitment [GO:0007465]; regulation of neuron differentiation [GO:0045664]; regulation of protein localization to nucleus [GO:1900180]; regulation of R7 cell differentiation [GO:0045676]; regulation of retinal cone cell fate specification [GO:0042673]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ development [GO:0007423]; sensory perception of taste [GO:0050909]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp72815_c0_seq1,1225,44.0816,0.52295872,44,74,,3.00E-147,Q6ZXV5,Transmembrane and TPR repeat-containing protein 3 (Protein SMILE),Transmembrane and TPR repeat-containing protein 3 (Protein SMILE),GO:0060447; GO:0016021; GO:0048286; GO:0048747; GO:0009791; GO:0010468,bud outgrowth involved in lung branching; integral to membrane; lung alveolus development; muscle fiber development; post-embryonic development; regulation of gene expression,PF08409;PF13174;PF13181;,1.00E-72,CHOYP_BRAFLDRAFT_199459.1.1,,,,,,,TMTC3_HUMAN,Homo sapiens (Human), comp72873_c0_seq1,250,40,0.34057533,13,0,,1.00E-20,Q64512,Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP),GO:0005737; GO:0005856; GO:0030027; GO:0005634; GO:0004725,cytoplasm; cytoskeleton; lamellipodium; nucleus; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,,,,,,,,,PTN13_MOUSE,Mus musculus (Mouse),peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp72923_c0_seq1,206,45.1456,0.19256268,2,2,,9.00E-11,Q6WQJ1,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0071926; GO:0016021; GO:0016042; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0004806,arachidonic acid metabolic process; endocannabinoid signaling pathway; integral to membrane; lipid catabolic process; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; triglyceride lipase activity,PF01764;,,,,,,,,,DGLA_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136] comp72955_c0_seq1,630,42.8571,0.416045,2,42,,,,,,,,,,,3.00E-68,ruditapes2_c2362,,,,,,, comp72982_c0_seq1,288,42.7083,0.53775236,11,8,,4.00E-25,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp73026_c0_seq1,273,42.1245,0.66344716,0,4,,5.00E-09,Q91ZI0,Cadherin EGF LAG seven-pass G-type receptor 3,Cadherin EGF LAG seven-pass G-type receptor 3,GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_MOUSE,Mus musculus (Mouse),axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp73053_c0_seq1,361,43.7673,0.46403176,0,37,,,,,,,,,9.00E-12,CHOYP_BRAFLDRAFT_121964.1.1,,,,,,,,, comp73054_c0_seq1,575,50.2609,0.44138065,13,21,,6.00E-86,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,1.00E-133,CHOYP_LOC577371.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp73064_c1_seq1,232,43.9655,1.3458086,7,6,,4.00E-21,Q6NVP8,"Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)","Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)",GO:0032580; GO:0036071; GO:0008424; GO:0016021; GO:0033578,Golgi cisterna membrane; N-glycan fucosylation; glycoprotein 6-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation in Golgi,PF14604;,,,,,,,,,FUT8_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] comp73085_c0_seq1,240,48.3333,0.67361418,0,32,,6.00E-38,Q16549,Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),GO:0030173; GO:0016486; GO:0006508; GO:0004252,integral to Golgi membrane; peptide hormone processing; proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,2.00E-29,CHOYP_PCSK7.1.1,,,,,,,PCSK7_HUMAN,Homo sapiens (Human),peptide hormone processing [GO:0016486]; protein processing [GO:0016485] comp73094_c0_seq1,295,47.1186,0.43275351,9,15,,3.00E-30,Q9VLS1,Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta),GO:0005977; GO:0004553; GO:0005886,"glycogen metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plasma membrane",PF00723;,2.00E-26,CHOYP_KPBB.2.2,,,,,,,KPBB_DROME,Drosophila melanogaster (Fruit fly),glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] comp73097_c0_seq1,540,43.3333,1.23416421,0,40,,4.00E-11,O75197,Low-density lipoprotein receptor-related protein 5 (LRP-5),Low-density lipoprotein receptor-related protein 5 (LRP-5),GO:0044332; GO:0042813; GO:0017147; GO:0060612; GO:0009952; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042632; GO:0015026; GO:0048596; GO:0030326; GO:0060059; GO:0006897; GO:0005783; GO:0001702; GO:0006007; GO:0016021; GO:0045668; GO:0071901; GO:0002076; GO:0005886; GO:0045600; GO:0002053; GO:0045840; GO:0045944; GO:0043235; GO:0008217; GO:0060828; GO:0061178; GO:0061304,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; Wnt-protein binding; adipose tissue development; anterior/posterior pattern specification; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cholesterol homeostasis; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic limb morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; gastrulation with mouth forming second; glucose catabolic process; integral to membrane; negative regulation of osteoblast differentiation; negative regulation of protein serine/threonine kinase activity; osteoblast development; plasma membrane; positive regulation of fat cell differentiation; positive regulation of mesenchymal cell proliferation; positive regulation of mitosis; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of blood pressure; regulation of canonical Wnt receptor signaling pathway; regulation of insulin secretion involved in cellular response to glucose stimulus; retinal blood vessel morphogenesis,PF00057;PF00058;,,,,,,,,,LRP5_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp73110_c0_seq1,222,40.991,0.10835983,7,10,,2.00E-12,Q9NYP3,Protein downstream neighbor of Son (B17),Protein downstream neighbor of Son (B17),GO:0007275; GO:0005634,multicellular organismal development; nucleus,,5.00E-12,CHOYP_LOC592697.1.1,,,,,,,DONS_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp73112_c0_seq1,233,45.9227,0.83872513,0,27,,4.00E-16,Q8IWU5,Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-),Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-),GO:0005795; GO:0008449; GO:0004065; GO:0060348; GO:0005509; GO:0009986; GO:0002063; GO:0048706; GO:0005783; GO:0014846; GO:0005615; GO:0035860; GO:0032836; GO:0003094; GO:0030201; GO:0060384; GO:0040037; GO:0005886; GO:0030177; GO:0010575,Golgi stack; N-acetylglucosamine-6-sulfatase activity; arylsulfatase activity; bone development; calcium ion binding; cell surface; chondrocyte development; embryonic skeletal system development; endoplasmic reticulum; esophagus smooth muscle contraction; extracellular space; glial cell-derived neurotrophic factor receptor signaling pathway; glomerular basement membrane development; glomerular filtration; heparan sulfate proteoglycan metabolic process; innervation; negative regulation of fibroblast growth factor receptor signaling pathway; plasma membrane; positive regulation of Wnt receptor signaling pathway; positive regulation vascular endothelial growth factor production,PF12548;PF00884;,,,,,,,,,SULF2_HUMAN,Homo sapiens (Human),bone development [GO:0060348]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; liver regeneration [GO:0097421]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of hepatocyte proliferation [GO:2000345]; response to wounding [GO:0009611] comp73151_c1_seq1,282,43.2624,0.53468958,14,7,,8.00E-34,Q6DFV5,Probable helicase with zinc finger domain (EC 3.6.4.-),Probable helicase with zinc finger domain (EC 3.6.4.-),GO:0005524; GO:0004386; GO:0046872; GO:0005634,ATP binding; helicase activity; metal ion binding; nucleus,PF00642;,,,,,,,,,HELZ_MOUSE,Mus musculus (Mouse), comp73194_c0_seq2,1087,36.7065,0.60307433,25,39,,1.00E-36,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp73205_c0_seq1,329,40.1216,0.46316217,7,0,,3.00E-07,Q5U374,Kelch-like protein 12,Kelch-like protein 12,GO:0048208; GO:0031463; GO:0030134; GO:0016055; GO:0009952; GO:0060028; GO:0006513,COPII vesicle coating; Cul3-RING ubiquitin ligase complex; ER to Golgi transport vesicle; Wnt receptor signaling pathway; anterior/posterior pattern specification; convergent extension involved in axis elongation; protein monoubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] comp73223_c0_seq1,471,36.0934,0.41037716,13,58,,1.00E-15,Q09429,ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1),ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1),GO:0005524; GO:0006200; GO:0008282; GO:0042626; GO:0046676; GO:0043268; GO:0005267; GO:0042493; GO:0032868; GO:0032496; GO:0009268; GO:0010043; GO:0042383; GO:0008281; GO:0030672; GO:0019905,"ATP binding; ATP catabolic process; ATP-sensitive potassium channel complex; ATPase activity, coupled to transmembrane movement of substances; negative regulation of insulin secretion; positive regulation of potassium ion transport; potassium channel activity; response to drug; response to insulin stimulus; response to lipopolysaccharide; response to pH; response to zinc ion; sarcolemma; sulfonylurea receptor activity; synaptic vesicle membrane; syntaxin binding",PF00664;PF00005;,,,,,,,,,ABCC8_RAT,Rattus norvegicus (Rat),cellular response to organic substance [GO:0071310]; negative regulation of insulin secretion [GO:0046676]; positive regulation of potassium ion transport [GO:0043268]; response to drug [GO:0042493]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; response to zinc ion [GO:0010043] comp73232_c0_seq1,288,40.2778,0.17264246,9,21,,5.00E-06,Q5FW17,Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1),Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1),GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0046872; GO:0005634,DNA binding; DNA recombination; DNA repair; DNA replication; metal ion binding; nucleus,PF04057;PF08646;PF16900;PF01336;,,,,,,,,,RFA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] comp73233_c0_seq1,278,39.9281,0.72515558,8,26,,6.00E-09,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp73361_c0_seq1,447,42.0582,1.21053237,12,22,,1.00E-21,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp73380_c0_seq1,218,41.2844,0.87209401,0,25,,3.00E-13,P42118,DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase),DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase),GO:0003677; GO:0006304; GO:0003912; GO:0003887; GO:0046872; GO:0005634,DNA binding; DNA modification; DNA nucleotidylexotransferase activity; DNA-directed DNA polymerase activity; metal ion binding; nucleus,PF14792;PF14791;PF10391;PF14716;,,,,,,,,,TDT_XENLA,Xenopus laevis (African clawed frog),DNA metabolic process [GO:0006259]; DNA modification [GO:0006304] comp73382_c0_seq1,291,62.1993,1.06987096,3,19,,3.00E-35,P40812,L-asparagine permease (L-asparagine transport protein),L-asparagine permease (L-asparagine transport protein),GO:0015171; GO:0016021; GO:0005886,amino acid transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,ANSP_SALTY,Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720), comp73391_c0_seq1,212,42.4528,0.42410102,6,13,,2.00E-23,Q5IGR8,Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a),Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a),GO:0050509; GO:0050508; GO:0015012; GO:0030176; GO:0006486,N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to endoplasmic reticulum membrane; protein glycosylation,PF03016;PF09258;,,,,,,,,,EXT1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486] comp73391_c1_seq1,265,40,0.47619726,6,12,,5.00E-41,Q9Y169,Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Protein sister of tout-velu),Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Protein sister of tout-velu),GO:0005794; GO:0000139; GO:0006044; GO:0050509; GO:0016055; GO:0030206; GO:0008101; GO:0005783; GO:0050508; GO:0015014; GO:0030210; GO:0016021; GO:0031227; GO:0007275; GO:0006486; GO:0007224,"Golgi apparatus; Golgi membrane; N-acetylglucosamine metabolic process; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; Wnt receptor signaling pathway; chondroitin sulfate biosynthetic process; decapentaplegic signaling pathway; endoplasmic reticulum; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; multicellular organismal development; protein glycosylation; smoothened signaling pathway",PF03016;PF09258;,5.00E-26,CHOYP_EXT2.1.1,,,,,,,EXT2_DROME,Drosophila melanogaster (Fruit fly),"chondroitin sulfate biosynthetic process [GO:0030206]; decapentaplegic signaling pathway [GO:0008101]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; multicellular organism development [GO:0007275]; N-acetylglucosamine metabolic process [GO:0006044]; protein glycosylation [GO:0006486]; smoothened signaling pathway [GO:0007224]; Wnt signaling pathway [GO:0016055]" comp73399_c0_seq1,888,42.2297,0.43212155,33,18,,5.00E-79,Q8TB40,Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Alpha/beta-hydrolase 4) (Lyso-N-acylphosphatidylethanolamine lipase),Protein ABHD4 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 4) (Abhydrolase domain-containing protein 4) (Alpha/beta-hydrolase 4) (Lyso-N-acylphosphatidylethanolamine lipase),GO:0016787; GO:0016042,hydrolase activity; lipid catabolic process,PF00561;,2.00E-44,CHOYP_ABHD4.1.1,,,,,,,ABHD4_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; phospholipid metabolic process [GO:0006644] comp73409_c0_seq1,1260,39.3651,0.38995793,40,30,,2.00E-29,Q4VBD9,GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GDNF-inducible zinc finger protein 1 (Zinc finger protein 336),GO:0001658; GO:0005737; GO:0046872; GO:0000122; GO:0005730; GO:0005634; GO:0043565; GO:0006351,"branching involved in ureteric bud morphogenesis; cytoplasm; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleolus; nucleus; sequence-specific DNA binding; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,GZF1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp73410_c0_seq1,262,59.1603,1.15586538,1,26,,1.00E-22,P94325,Citrate synthase (EC 2.3.3.1),Citrate synthase (EC 2.3.3.16),GO:0044262; GO:0004108; GO:0005737; GO:0006099,cellular carbohydrate metabolic process; citrate (Si)-synthase activity; cytoplasm; tricarboxylic acid cycle,PF00285;,,,,,,,,,CISY_BRAJA,Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110),tricarboxylic acid cycle [GO:0006099] comp73435_c0_seq1,217,43.7788,0.29067284,6,0,,2.00E-11,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp73437_c0_seq1,228,35.9649,0.28324602,0,7,,1.00E-07,Q9ERV7,p53-induced protein with a death domain (Leucine-rich repeat and death domain-containing protein),p53-induced death domain-containing protein 1 (Leucine-rich repeat and death domain-containing protein),GO:0006977; GO:0006919; GO:0005737; GO:0043066; GO:0005634; GO:1902043,"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; activation of cysteine-type endopeptidase activity involved in apoptotic process; cytoplasm; negative regulation of apoptotic process; nucleus; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors",PF00531;PF13855;PF10461;PF00791;,,,,,,,,,PIDD_MOUSE,Mus musculus (Mouse),"activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]" comp73439_c0_seq1,252,52.7778,0.806479,9,2,,3.00E-27,Q7T2Z5,Netrin receptor UNC5C (Protein unc-5 homolog 3) (cUNC-5H3) (Protein unc-5 homolog C),Netrin receptor UNC5C (Protein unc-5 homolog 3) (cUNC-5H3) (Protein unc-5 homolog C),GO:0016021; GO:0007275; GO:0007165,integral to membrane; multicellular organismal development; signal transduction,PF00531;PF07679;PF00090;PF00791;,,,,,,,,,UNC5C_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275]; signal transduction [GO:0007165] comp73439_c1_seq1,221,49.7738,0.36890087,4,7,,2.00E-13,Q6ZN44,Netrin receptor UNC5A (Protein unc-5 homolog 1) (Protein unc-5 homolog A),Netrin receptor UNC5A (Protein unc-5 homolog 1) (Protein unc-5 homolog A),GO:0033564; GO:0006915; GO:0007411; GO:0016021; GO:0005886; GO:0043065; GO:0007165,anterior/posterior axon guidance; apoptotic process; axon guidance; integral to membrane; plasma membrane; positive regulation of apoptotic process; signal transduction,PF00531;PF07679;PF00791;,2.00E-11,CHOYP_LOC100569275.1.1,,,,,,,UNC5A_HUMAN,Homo sapiens (Human),anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; netrin-activated signaling pathway [GO:0038007]; neuron projection development [GO:0031175] comp73442_c0_seq1,737,43.2836,1.07997351,14,53,,2.00E-21,Q99NA2,Protein atonal homolog 8 (Helix-loop-helix protein mATH-6) (mATH6) (Okadin),Protein atonal homolog 8 (Helix-loop-helix protein mATH-6) (mATH6) (Okadin),GO:0003677; GO:0030154; GO:0007399; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cell differentiation; nervous system development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00010;,7.00E-23,CHOYP_ATOH8.1.1,,,,,,,ATOH8_MOUSE,Mus musculus (Mouse),"cell differentiation [GO:0030154]; formation of primary germ layer [GO:0001704]; myoblast proliferation [GO:0051450]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription, DNA-templated [GO:0045893]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]" comp73463_c0_seq1,447,44.2953,0.41562934,3,39,,,,,,,,,1.00E-30,CHOYP_contig_045436,,,,,,,,, comp73465_c1_seq1,216,38.4259,0.25380661,2,7,,,,,,,,,2.00E-16,CHOYP_contig_006588,,,,,,,,, comp73471_c0_seq1,293,43.686,1.15097989,4,21,,3.00E-20,Q9D6X5,"Solute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (RFT2)","Solute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (RFT2)",GO:0034605; GO:0005887; GO:0032217; GO:0007605,cellular response to heat; integral to plasma membrane; riboflavin transporter activity; sensory perception of sound,PF06237;,,,,,,,,,S52A3_MOUSE,Mus musculus (Mouse),cellular response to heat [GO:0034605]; riboflavin transport [GO:0032218]; sensory perception of sound [GO:0007605] comp73473_c0_seq1,313,48.2428,0.55282254,9,3,,4.00E-23,P10731,Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)],Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)],GO:0031418; GO:0005507; GO:0016021; GO:0006518; GO:0004598; GO:0004504; GO:0030658,L-ascorbic acid binding; copper ion binding; integral to membrane; peptide metabolic process; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; transport vesicle membrane,PF03712;PF01082;PF01436;,9.00E-11,CHOYP_PAM.1.1,,,,,,,AMD_BOVIN,Bos taurus (Bovine),peptide metabolic process [GO:0006518] comp73486_c0_seq1,726,41.0468,0.20536762,2,28,,2.00E-53,Q5RI75,Ras and EF-hand domain-containing protein homolog,Ras and EF-hand domain-containing protein homolog,GO:0005525; GO:0048471; GO:0015031; GO:0007264,GTP binding; perinuclear region of cytoplasm; protein transport; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RASEF_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp73486_c0_seq2,453,44.8124,0.27158657,0,0,,8.00E-24,Q5UQ27,Probable Rab-related GTPase,Probable Rab-related GTPase,GO:0005525; GO:0020002; GO:0016020; GO:0015031; GO:0007264,GTP binding; host cell plasma membrane; membrane; protein transport; small GTPase mediated signal transduction,PF00071;,2.00E-53,CHOYP_LOC100377113.1.3,2.00E-12,ruditapes_c7176,,,,,RABL_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp73503_c0_seq1,432,62.2685,0.98300637,0,29,,2.00E-08,Q57252,Uncharacterized protein HI_1163,Uncharacterized protein HI_1163,GO:0008762; GO:0050660; GO:0051536,UDP-N-acetylmuramate dehydrogenase activity; flavin adenine dinucleotide binding; iron-sulfur cluster binding,PF02913;PF01565;PF13183;,,,,,,,,,Y1163_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp73507_c0_seq1,249,32.5301,0.16846633,10,4,,3.00E-13,Q96F63,Coiled-coil domain-containing protein 97,Coiled-coil domain-containing protein 97,,,PF09747;,1.00E-21,CHOYP_LOC100370539.1.1,,,,,,,CCD97_HUMAN,Homo sapiens (Human), comp73508_c0_seq1,898,38.7528,1.06985026,24,6,,2.00E-07,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp73533_c0_seq1,206,36.8932,1.00627371,0,8,,3.00E-10,Q14585,Zinc finger protein 345 (Zinc finger protein HZF10),Zinc finger protein 345 (Zinc finger protein HZF10),GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006359; GO:0006366; GO:0006383,DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter,PF00096;PF13912;PF13465;,,,,,,,,,ZN345_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366] comp73540_c0_seq1,334,44.3114,0.79894314,3,23,,8.00E-16,Q00519,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0006919; GO:0009055; GO:0005576; GO:0050660; GO:0005506; GO:0007595; GO:0030151; GO:0043546; GO:0045602; GO:0001937; GO:0010629; GO:0051898; GO:0001933; GO:1900747; GO:2001213; GO:0005777; GO:1900745; GO:2000379; GO:0030856; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; electron carrier activity; extracellular region; flavin adenine dinucleotide binding; iron ion binding; lactation; molybdenum ion binding; molybdopterin cofactor binding; negative regulation of endothelial cell differentiation; negative regulation of endothelial cell proliferation; negative regulation of gene expression; negative regulation of protein kinase B signaling cascade; negative regulation of protein phosphorylation; negative regulation of vascular endothelial growth factor signaling pathway; negative regulation of vasculogenesis; peroxisome; positive regulation of p38MAPK cascade; positive regulation of reactive oxygen species metabolic process; regulation of epithelial cell differentiation; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; lactation [GO:0007595]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of gene expression [GO:0010629]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; negative regulation of vasculogenesis [GO:2001213]; oxidation-reduction process [GO:0055114]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of epithelial cell differentiation [GO:0030856]; xanthine catabolic process [GO:0009115] comp73575_c0_seq1,567,38.6243,0.56876011,22,37,,2.00E-35,Q9D9N8,Protease-associated domain-containing protein 1 (Protease-associated domain-containing protein of 21 kDa),Protease-associated domain-containing protein 1 (Protease-associated domain-containing protein of 21 kDa),GO:0005576,extracellular region,PF02225;,3.00E-14,CHOYP_NEMVEDRAFT_V1G187084.1.1,,,,,,,PADC1_MOUSE,Mus musculus (Mouse), comp73585_c0_seq1,391,36.5729,1.01111772,13,11,,,,,,,,,3.00E-18,CHOYP_NEMVEDRAFT_V1G244806.2.2,,,,,,,,, comp73591_c0_seq1,204,61.7647,0.8297695,0,17,,2.00E-21,Q6A9J2,Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase),Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase),GO:0005737; GO:0006094; GO:0006096; GO:0006098; GO:0004807,cytoplasm; gluconeogenesis; glycolysis; pentose-phosphate shunt; triose-phosphate isomerase activity,PF00121;,,,,,,,,,TPIS_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098] comp73604_c0_seq1,239,39.749,0.63830905,2,8,,2.00E-09,Q9FJR0,Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-) (ATP-dependent helicase UPF1),Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-) (ATP-dependent helicase UPF1),GO:0005524; GO:0003677; GO:0003723; GO:0016246; GO:0000932; GO:0005829; GO:0042742; GO:0004386; GO:0009867; GO:0048571; GO:0000184; GO:0005886; GO:0009506; GO:0009744; GO:0009611; GO:0009863; GO:0010182; GO:0008270,"ATP binding; DNA binding; RNA binding; RNA interference; cytoplasmic mRNA processing body; cytosol; defense response to bacterium; helicase activity; jasmonic acid mediated signaling pathway; long-day photoperiodism; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; plasma membrane; plasmodesma; response to sucrose stimulus; response to wounding; salicylic acid mediated signaling pathway; sugar mediated signaling pathway; zinc ion binding",PF09416;,,,,,,,,,RENT1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; long-day photoperiodism [GO:0048571]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; response to wounding [GO:0009611]; salicylic acid mediated signaling pathway [GO:0009863]; sugar mediated signaling pathway [GO:0010182]" comp73605_c0_seq1,498,61.6466,0.91074221,3,10,,9.00E-14,P96687,Membrane protein YdfJ,Membrane protein YdfJ,GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF03176;,,,,,,,,,YDFJ_BACSU,Bacillus subtilis (strain 168), comp73616_c0_seq1,273,42.4908,0.89623564,6,0,,7.00E-29,A1L3M3,Y+L amino acid transporter 2 (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2),Y+L amino acid transporter 2 (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2),GO:0015171; GO:0016323; GO:0016021,amino acid transmembrane transporter activity; basolateral plasma membrane; integral to membrane,PF13520;,4.00E-14,CHOYP_LOC411935.1.1,,,,,,,YLAT2_XENLA,Xenopus laevis (African clawed frog), comp73652_c0_seq1,306,48.366,0.76943178,13,0,,,,,,,,,8.00E-37,CHOYP_LOC100372012.1.1,,,,,,,,, comp73652_c1_seq1,350,43.4286,0.74207794,8,0,,1.00E-23,O14513,Nck-associated protein 5 (NAP-5) (Peripheral clock protein),Nck-associated protein 5 (NAP-5) (Peripheral clock protein),,,PF15246;,,,,,,,,,NCKP5_HUMAN,Homo sapiens (Human), comp73657_c0_seq1,305,42.2951,0.96930867,4,18,,6.00E-06,Q9R016,Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5),Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5),GO:0005524; GO:0072557; GO:0006915; GO:0050829; GO:0016045; GO:0006954; GO:0045087; GO:0046872; GO:0070269,ATP binding; IPAF inflammasome complex; apoptotic process; defense response to Gram-negative bacterium; detection of bacterium; inflammatory response; innate immune response; metal ion binding; pyroptosis,PF00653;,,,,,,,,,BIR1E_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; detection of bacterium [GO:0016045]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pyroptosis [GO:0070269]; regulation of signal transduction [GO:0009966] comp73672_c0_seq1,359,45.1253,0.16463542,10,13,,2.00E-14,O60081,Uncharacterized protein C1494.07,Uncharacterized protein C1494.07,GO:0005829; GO:0005634; GO:0043234; GO:0030488,cytosol; nucleus; protein complex; tRNA methylation,PF10350;,,,,,,,,,YQK7_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),tRNA methylation [GO:0030488] comp73684_c0_seq1,963,47.2482,0.61973709,40,27,,4.00E-145,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,3.00E-99,CHOYP_LOC100369716.1.1,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp73689_c0_seq1,295,62.7119,1.13113313,1,15,,4.00E-16,P59968,Uncharacterized tRNA/rRNA methyltransferase Mb0905 (EC 2.1.1.-),Uncharacterized tRNA/rRNA methyltransferase Mb0905 (EC 2.1.1.-),GO:0003723; GO:0001510; GO:0008173; GO:0006396,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing,PF00588;,,,,,,,,,Y905_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),RNA processing [GO:0006396] comp73692_c0_seq1,256,57.0312,1.001379,0,17,,1.00E-10,Q9L1A5,Arginine repressor,Arginine repressor,GO:0003677; GO:0034618; GO:0006526; GO:0005737; GO:0051259; GO:0003700; GO:0006351,"DNA binding; arginine binding; arginine biosynthetic process; cytoplasm; protein oligomerization; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01316;PF02863;,,,,,,,,,ARGR_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),"arginine biosynthetic process [GO:0006526]; protein oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]" comp73695_c0_seq1,360,62.2222,1.35304074,3,15,,6.00E-18,Q9K4E3,Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.n16) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC),Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC),GO:0003676; GO:0018364; GO:0036009,nucleic acid binding; peptidyl-glutamine methylation; protein-glutamine N-methyltransferase activity,PF05175;,,,,,,,,,PRMC_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),peptidyl-glutamine methylation [GO:0018364] comp73718_c0_seq1,233,46.3519,0.64552913,9,14,,2.00E-25,P55162,Membrane-associated protein Hem (dHem-2),Membrane-associated protein Hem (dHem-2),GO:0031209; GO:0007409; GO:0030031; GO:0007417; GO:0008407; GO:0030866; GO:0016021; GO:0007520; GO:0007528; GO:0001764; GO:0006909; GO:0005886; GO:0008360,SCAR complex; axonogenesis; cell projection assembly; central nervous system development; chaeta morphogenesis; cortical actin cytoskeleton organization; integral to membrane; myoblast fusion; neuromuscular junction development; neuron migration; phagocytosis; plasma membrane; regulation of cell shape,PF09735;,4.00E-13,CHOYP_NCKP1.2.4,,,,,,,HEM_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; cell adhesion mediated by integrin [GO:0033627]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; neuron migration [GO:0001764]; oocyte growth [GO:0001555]; phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360] comp73786_c1_seq1,243,48.5597,0.07017663,3,0,,6.00E-15,O43826,Glucose-6-phosphate translocase (Glucose-5-phosphate transporter) (Solute carrier family 37 member 4) (Transformation-related gene 19 protein) (TRG-19),Glucose-6-phosphate exchanger SLC37A4 (Glucose-5-phosphate transporter) (Glucose-6-phosphate translocase) (Solute carrier family 37 member 4) (Transformation-related gene 19 protein) (TRG-19),GO:0005789; GO:0042593; GO:0006006; GO:0015758; GO:0015152; GO:0030176; GO:0016021; GO:0044281,endoplasmic reticulum membrane; glucose homeostasis; glucose metabolic process; glucose transport; glucose-6-phosphate transmembrane transporter activity; integral to endoplasmic reticulum membrane; integral to membrane; small molecule metabolic process,PF07690;,,,,,,,,,G6PT1_HUMAN,Homo sapiens (Human),glucose-6-phosphate transport [GO:0015760]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glucose transport [GO:0015758]; mitophagy in response to mitochondrial depolarization [GO:0098779]; phosphate ion transmembrane transport [GO:0035435]; positive regulation of defense response to virus by host [GO:0002230]; transport [GO:0006810]; xenophagy [GO:0098792] comp73789_c1_seq1,215,53.9535,1.05271848,0,5,,2.00E-39,P42798,40S ribosomal protein S15a-1,40S ribosomal protein S15a-1,GO:0005618; GO:0022627; GO:0005886; GO:0009506; GO:0003735; GO:0006412; GO:0005774,cell wall; cytosolic small ribosomal subunit; plasma membrane; plasmodesma; structural constituent of ribosome; translation; vacuolar membrane,PF00410;,,,6.00E-21,ruditapes2_c203,,,,,R15A1_ARATH,Arabidopsis thaliana (Mouse-ear cress),translation [GO:0006412] comp73810_c0_seq1,642,45.7944,0.76094859,27,0,,6.00E-63,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,1.00E-75,CHOYP_HMCN1.28.44,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp73818_c1_seq1,449,46.3252,0.83705772,16,30,,4.00E-08,O94810,Regulator of G-protein signaling 11 (RGS11),Regulator of G-protein signaling 11 (RGS11),GO:0007186; GO:0005096; GO:0005737; GO:0044292; GO:0005834; GO:0035556; GO:0005886; GO:0043234; GO:0008277; GO:0004871; GO:0038032,G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; dendrite terminus; heterotrimeric G-protein complex; intracellular signal transduction; plasma membrane; protein complex; regulation of G-protein coupled receptor protein signaling pathway; signal transducer activity; termination of G-protein coupled receptor signaling pathway,PF00610;PF00631;PF00615;,,,,,,,,,RGS11_HUMAN,Homo sapiens (Human),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp73849_c1_seq1,214,45.3271,0.82977798,7,11,,1.00E-12,A4IF63,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_BOVIN,Bos taurus (Bovine),regulation of neuron apoptotic process [GO:0043523] comp73854_c0_seq1,259,72.973,0.96082059,0,14,,3.00E-20,P00632,3-oxoadipate enol-lactonase 2 (EC 3.1.1.24) (3-oxoadipate enol-lactonase II) (Beta-ketoadipate enol-lactone hydrolase II) (Enol-lactone hydrolase II),3-oxoadipate enol-lactonase 2 (EC 3.1.1.24) (3-oxoadipate enol-lactonase II) (Beta-ketoadipate enol-lactone hydrolase II) (Enol-lactone hydrolase II),GO:0047570; GO:0042952,3-oxoadipate enol-lactonase activity; beta-ketoadipate pathway,PF12146;,,,,,,,,,ELH2_ACIAD,Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1),beta-ketoadipate pathway [GO:0042952] comp73864_c0_seq1,249,36.9478,0.36285055,5,0,,5.00E-18,Q90YB1,DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4),DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4),GO:0005524; GO:0003677; GO:0003910; GO:0032807; GO:0051103; GO:0033151; GO:0007049; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0046872; GO:0070419; GO:0005654; GO:0006289,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase IV complex; DNA ligation involved in DNA repair; V(D)J recombination; cell cycle; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; metal ion binding; nonhomologous end joining complex; nucleoplasm; nucleotide-excision repair,PF00533;PF04679;PF01068;PF04675;PF11411;,,,,,,,,,DNLI4_CHICK,Gallus gallus (Chicken),"cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; nucleotide-excision repair, DNA gap filling [GO:0006297]" comp73865_c0_seq1,400,44.5,0.56263107,22,35,,2.00E-51,Q9GKU5,Histone deacetylase 11 (HD11) (EC 3.5.1.98),Histone deacetylase 11 (HD11) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0006355; GO:0008134; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF00850;,6.00E-52,CHOYP_HDA11.1.1,,,,,,,HDA11_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp73878_c0_seq1,247,45.3441,1.03103705,3,8,,3.00E-26,Q5R4M8,Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)],Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)],GO:0005524; GO:0055129; GO:0019240; GO:0004349; GO:0006536; GO:0004350; GO:0005743; GO:0006561,ATP binding; L-proline biosynthetic process; citrulline biosynthetic process; glutamate 5-kinase activity; glutamate metabolic process; glutamate-5-semialdehyde dehydrogenase activity; mitochondrial inner membrane; proline biosynthetic process,PF00696;PF00171;,,,,,,,,,P5CS_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561] comp73882_c0_seq1,227,43.6123,0.373166,5,10,,2.00E-15,P81282,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp73882_c1_seq1,501,45.509,0.42650977,9,12,,7.00E-42,P07207,Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein],GO:0005796; GO:0061382; GO:0007219; GO:0048052; GO:0007464; GO:0045466; GO:0045463; GO:0007460; GO:0007015; GO:0005912; GO:0008356; GO:0007298; GO:0005509; GO:0009986; GO:0008407; GO:0003682; GO:0042676; GO:0046667; GO:0005829; GO:0008340; GO:0046843; GO:0007391; GO:0007451; GO:0007398; GO:0035165; GO:0005788; GO:0005768; GO:0061331; GO:0035153; GO:0035214; GO:0007440; GO:0060288; GO:0030718; GO:0030708; GO:0007403; GO:0008347; GO:0035172; GO:0007157; GO:0007446; GO:0016348; GO:0048803; GO:0008587; GO:0007474; GO:0016021; GO:0035171; GO:0046331; GO:0007616; GO:0035170; GO:0007498; GO:0008045; GO:0007521; GO:0046329; GO:0045316; GO:0035157; GO:0050768; GO:0035155; GO:0000122; GO:0007400; GO:0005654; GO:0007314; GO:0030720; GO:0030713; GO:0007422; GO:1900087; GO:0045747; GO:0008284; GO:0045944; GO:0043234; GO:0045468; GO:0042686; GO:0042689; GO:0051489; GO:0040008; GO:0009608; GO:0016330; GO:0007519; GO:0035003; GO:0006351; GO:0004888; GO:0007419; GO:0048190; GO:0007473,"Golgi lumen; Malpighian tubule tip cell differentiation; Notch signaling pathway; R1/R6 cell differentiation; R3/R4 cell fate commitment; R7 cell differentiation; R8 cell development; R8 cell fate commitment; actin filament organization; adherens junction; asymmetric cell division; border follicle cell migration; calcium ion binding; cell surface; chaeta morphogenesis; chromatin binding; compound eye cone cell fate commitment; compound eye retinal cell programmed cell death; cytosol; determination of adult lifespan; dorsal appendage formation; dorsal closure; dorsal/ventral lineage restriction, imaginal disc; ectoderm development; embryonic crystal cell differentiation; endoplasmic reticulum lumen; endosome; epithelial cell proliferation involved in Malpighian tubule morphogenesis; epithelial cell type specification, open tracheal system; eye-antennal disc development; foregut morphogenesis; formation of a compartment boundary; germ-line stem cell maintenance; germarium-derived female germ-line cyst encapsulation; glial cell fate determination; glial cell migration; hemocyte proliferation; heterophilic cell-cell adhesion; imaginal disc growth; imaginal disc-derived leg joint morphogenesis; imaginal disc-derived male genitalia morphogenesis; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein specification; integral to membrane; lamellocyte differentiation; lateral inhibition; long-term memory; lymph gland crystal cell differentiation; mesoderm development; motor neuron axon guidance; muscle cell fate determination; negative regulation of JNK cascade; negative regulation of compound eye photoreceptor development; negative regulation of fusion cell fate specification; negative regulation of neurogenesis; negative regulation of terminal cell fate specification, open tracheal system; negative regulation of transcription from RNA polymerase II promoter; neuroblast fate determination; nucleoplasm; oocyte anterior/posterior axis specification; oocyte localization involved in germarium-derived egg chamber formation; ovarian follicle cell stalk formation; peripheral nervous system development; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of Notch signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein complex; regulation of R8 cell spacing in compound eye; regulation of cardioblast cell fate specification; regulation of crystal cell differentiation; regulation of filopodium assembly; regulation of growth; response to symbiont; second mitotic wave involved in compound eye morphogenesis; skeletal muscle tissue development; subapical complex; transcription, DNA-dependent; transmembrane signaling receptor activity; ventral cord development; wing disc dorsal/ventral pattern formation; wing disc proximal/distal pattern formation",PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;,,,,,,,,,NOTCH_DROME,Drosophila melanogaster (Fruit fly),"actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]" comp73883_c0_seq1,297,45.7912,0.38971671,12,13,,2.00E-36,Q91XQ0,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0031514,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; motile cilium,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-51,CHOYP_LOC577371.1.2,4.00E-12,ruditapes_c7296,,,,,DYH8_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp73891_c0_seq1,391,43.734,0.53669573,15,0,,9.00E-21,Q9H5I5,Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B),Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B),GO:0005261; GO:0006812; GO:0016021; GO:0008381; GO:0042391,cation channel activity; cation transport; integral to membrane; mechanically-gated ion channel activity; regulation of membrane potential,PF15917;PF12166;,,,,,,,,,PIEZ2_HUMAN,Homo sapiens (Human),cation transport [GO:0006812]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; response to mechanical stimulus [GO:0009612] comp73896_c0_seq1,234,42.735,0.282118,0,11,,1.00E-28,Q2KJ28,"CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)","CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)",GO:0005524; GO:0008444; GO:0005783; GO:0005739; GO:0006655,ATP binding; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity; endoplasmic reticulum; mitochondrion; phosphatidylglycerol biosynthetic process,,,,,,,,,,PGPS1_BOVIN,Bos taurus (Bovine),phosphatidylglycerol biosynthetic process [GO:0006655] comp73896_c1_seq2,319,42.3197,0.53156669,2,18,,5.00E-26,Q5ZHN9,"CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)","CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)",GO:0005524; GO:0008444; GO:0005783; GO:0005739; GO:0006655,ATP binding; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity; endoplasmic reticulum; mitochondrion; phosphatidylglycerol biosynthetic process,,,,,,,,,,PGPS1_CHICK,Gallus gallus (Chicken),phosphatidylglycerol biosynthetic process [GO:0006655] comp73907_c1_seq1,334,46.1078,0.50929511,11,11,,1.00E-36,P43125,Protein retinal degeneration B (Probable calcium transporter rdgB),Protein retinal degeneration B (Probable calcium transporter rdgB),GO:0005388; GO:0016059; GO:0005887; GO:0046872; GO:0008525; GO:0046488; GO:0008526; GO:0016056; GO:0007608; GO:0016029; GO:0007601,calcium-transporting ATPase activity; deactivation of rhodopsin mediated signaling; integral to plasma membrane; metal ion binding; phosphatidylcholine transporter activity; phosphatidylinositol metabolic process; phosphatidylinositol transporter activity; rhodopsin mediated signaling pathway; sensory perception of smell; subrhabdomeral cisterna; visual perception,PF02862;PF02121;,3.00E-36,CHOYP_PITM2.2.2,,,,,,,RDGB_DROME,Drosophila melanogaster (Fruit fly),"cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; phosphatidylinositol metabolic process [GO:0046488]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]" comp73951_c0_seq1,477,47.5891,0.34115931,16,23,,5.00E-28,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,3.00E-31,CHOYP_LOC100377364.2.2,,,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp73974_c0_seq1,242,39.6694,0.10588416,7,0,,3.00E-07,Q9H0J9,Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),GO:0003950; GO:0046872; GO:0005634,NAD+ ADP-ribosyltransferase activity; metal ion binding; nucleus,PF00644;PF02825;PF00642;,,,,,,,,,PAR12_HUMAN,Homo sapiens (Human), comp73995_c0_seq1,299,41.4716,0.71147041,6,23,,8.00E-32,Q9NUJ3,T-complex protein 11-like protein 1,T-complex protein 11-like protein 1,GO:0005874,microtubule,PF05794;,7.00E-31,CHOYP_LOC100372245.1.1,,,,,,,T11L1_HUMAN,Homo sapiens (Human), comp73999_c0_seq1,534,44.7566,0.37465117,6,41,,6.00E-40,Q96AA3,Protein RFT1 homolog,Protein RFT1 homolog,GO:0008643; GO:0006488; GO:0016021; GO:0005319; GO:0043687; GO:0018279,carbohydrate transport; dolichol-linked oligosaccharide biosynthetic process; integral to membrane; lipid transporter activity; post-translational protein modification; protein N-linked glycosylation via asparagine,PF04506;,5.00E-11,CHOYP_BRAFLDRAFT_93651.1.1,,,,,,,RFT1_HUMAN,Homo sapiens (Human),carbohydrate transport [GO:0008643]; glycolipid translocation [GO:0034203] comp74004_c0_seq1,529,37.8072,1.00740656,18,18,,3.00E-06,P59511,A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-),A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-),GO:0030198; GO:0005615; GO:0004222; GO:0043066; GO:0045636; GO:0009967; GO:0005578; GO:0006508; GO:0008270,extracellular matrix organization; extracellular space; metalloendopeptidase activity; negative regulation of apoptotic process; positive regulation of melanocyte differentiation; positive regulation of signal transduction; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF08685;PF01562;PF01421;PF00090;,,,,,,,,,ATS20_MOUSE,Mus musculus (Mouse),extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]; proteolysis [GO:0006508]; regulation of developmental pigmentation [GO:0048070] comp74014_c0_seq1,278,47.8417,0.80675743,10,11,,5.00E-08,O75197,Low-density lipoprotein receptor-related protein 5 (LRP-5),Low-density lipoprotein receptor-related protein 5 (LRP-5),GO:0044332; GO:0042813; GO:0017147; GO:0060612; GO:0009952; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042632; GO:0015026; GO:0048596; GO:0030326; GO:0060059; GO:0006897; GO:0005783; GO:0001702; GO:0006007; GO:0016021; GO:0045668; GO:0071901; GO:0002076; GO:0005886; GO:0045600; GO:0002053; GO:0045840; GO:0045944; GO:0043235; GO:0008217; GO:0060828; GO:0061178; GO:0061304,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; Wnt-protein binding; adipose tissue development; anterior/posterior pattern specification; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cholesterol homeostasis; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic limb morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; gastrulation with mouth forming second; glucose catabolic process; integral to membrane; negative regulation of osteoblast differentiation; negative regulation of protein serine/threonine kinase activity; osteoblast development; plasma membrane; positive regulation of fat cell differentiation; positive regulation of mesenchymal cell proliferation; positive regulation of mitosis; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of blood pressure; regulation of canonical Wnt receptor signaling pathway; regulation of insulin secretion involved in cellular response to glucose stimulus; retinal blood vessel morphogenesis,PF00057;PF00058;,,,,,,,,,LRP5_HUMAN,Homo sapiens (Human),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp74019_c0_seq1,424,38.6792,0.31907084,12,23,,4.00E-55,Q922B6,E3 ubiquitin-protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor-associated factor 7),E3 ubiquitin-protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor-associated factor 7),GO:0000185; GO:0016023; GO:0097194; GO:0005886; GO:0043410; GO:0006355; GO:0006351; GO:0000151; GO:0004842; GO:0008270,"activation of MAPKKK activity; cytoplasmic membrane-bounded vesicle; execution phase of apoptosis; plasma membrane; positive regulation of MAPK cascade; regulation of transcription, DNA-dependent; transcription, DNA-dependent; ubiquitin ligase complex; ubiquitin-protein ligase activity; zinc ion binding",PF00400;PF13445;,7.00E-58,CHOYP_TRAF7.1.1,,,,,,,TRAF7_MOUSE,Mus musculus (Mouse),"activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cellular response to interleukin-6 [GO:0071354]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein sumoylation [GO:0033235]; protein ubiquitination [GO:0016567]; regulation of protein localization [GO:0032880]; transcription, DNA-templated [GO:0006351]" comp74029_c0_seq1,206,41.7476,0.56098883,3,8,,4.00E-15,Q28J44,Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11),Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11),GO:0016021; GO:0046873; GO:0006829,integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,,,,,,,,,S39AB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),zinc II ion transmembrane transport [GO:0071577] comp74039_c0_seq1,600,41.3333,0.66486812,24,10,,9.00E-58,Q8BX57,"PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)","PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)",GO:0005524; GO:0007154; GO:0005813; GO:0005737; GO:0006954; GO:0032780; GO:0043271; GO:0005634; GO:0035091; GO:0005886; GO:0004672; GO:0050804,ATP binding; cell communication; centrosome; cytoplasm; inflammatory response; negative regulation of ATPase activity; negative regulation of ion transport; nucleus; phosphatidylinositol binding; plasma membrane; protein kinase activity; regulation of synaptic transmission,PF00069;PF00787;PF02205;,,,,,,,,,PXK_MOUSE,Mus musculus (Mouse),inflammatory response [GO:0006954]; modulation of synaptic transmission [GO:0050804]; negative regulation of ATPase activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; regulation of membrane potential [GO:0042391] comp74041_c0_seq2,261,47.8927,0.13804207,3,1,,3.00E-10,Q6UX73,UPF0764 protein C16orf89,UPF0764 protein C16orf89,GO:0005576,extracellular region,PF15882;,,,,,,,,,CP089_HUMAN,Homo sapiens (Human), comp74041_c0_seq4,312,39.7436,0.25740396,0,0,,2.00E-09,Q8N2A0,Putative uncharacterized protein encoded by LINC00269,Putative uncharacterized protein encoded by LINC00269,,,,3.00E-11,CHOYP_RN7SL2.1.1,,,,,,,CX062_HUMAN,Homo sapiens (Human), comp74042_c1_seq1,665,49.1729,0.87297029,27,8,,,,,,,,,9.00E-15,CHOYP_LOC756958.2.2,,,,,,,,, comp74081_c0_seq1,440,45.6818,0.35181674,16,8,,1.00E-08,Q9NPA5,"Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)","Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)",GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13912;,,,,,,,,,ZF64A_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp74101_c0_seq1,577,36.7418,0.56997034,14,28,,8.00E-22,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp74106_c1_seq1,382,44.2408,0.26979616,9,11,,5.00E-29,Q8BHY8,Sorting nexin-14,Sorting nexin-14,GO:0007154; GO:0016021; GO:0035091; GO:0015031; GO:0038032,cell communication; integral to membrane; phosphatidylinositol binding; protein transport; termination of G-protein coupled receptor signaling pathway,PF08628;PF00787;PF02194;PF00615;,,,,,,,,,SNX14_MOUSE,Mus musculus (Mouse),autophagosome maturation [GO:0097352]; protein transport [GO:0015031] comp74109_c0_seq1,301,42.8571,0.73587557,3,8,,8.00E-15,Q5ZMC3,"WD repeat, SAM and U-box domain-containing protein 1","WD repeat, SAM and U-box domain-containing protein 1",GO:0000151; GO:0004842,ubiquitin ligase complex; ubiquitin-protein ligase activity,PF07647;PF04564;PF00400;,4.00E-27,CHOYP_LOC100893535.1.1,,,,,,,WSDU1_CHICK,Gallus gallus (Chicken), comp74109_c1_seq1,344,47.6744,0.36574593,12,7,,3.00E-09,Q7ZVF0,POC1 centriolar protein homolog A (WD repeat domain 51A),POC1 centriolar protein homolog A (WD repeat domain 51A),GO:0030030,cell projection organization,PF00400;,,,,,,,,,POC1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell projection organization [GO:0030030] comp74129_c0_seq1,236,43.6441,0.27558634,2,0,,4.00E-34,Q8BGQ7,"Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)","Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)",GO:0005524; GO:0004813; GO:0006419; GO:0016597; GO:0002161; GO:0021680; GO:0005737; GO:0030968; GO:0001942; GO:0046872; GO:0043524; GO:0050885; GO:0006457; GO:0043200; GO:0000049; GO:0006400,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; amino acid binding; aminoacyl-tRNA editing activity; cerebellar Purkinje cell layer development; cytoplasm; endoplasmic reticulum unfolded protein response; hair follicle development; metal ion binding; negative regulation of neuron apoptotic process; neuromuscular process controlling balance; protein folding; response to amino acid stimulus; tRNA binding; tRNA modification,PF02272;PF01411;PF07973;,4.00E-13,CHOYP_SYAC.1.2,,,,,,,SYAC_MOUSE,Mus musculus (Mouse),alanyl-tRNA aminoacylation [GO:0006419]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; endoplasmic reticulum unfolded protein response [GO:0030968]; hair follicle development [GO:0001942]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; protein folding [GO:0006457]; response to amino acid [GO:0043200]; skin development [GO:0043588]; tRNA modification [GO:0006400] comp74136_c1_seq1,435,43.6782,0.53194602,7,8,,,,,,,,,,,2.00E-12,ruditapes_c31843,,,,,,, comp74172_c0_seq1,341,41.349,0.55273203,7,49,,1.00E-38,Q6ZPR4,Potassium channel subfamily T member 1,Potassium channel subfamily T member 1,GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,1.00E-60,CHOYP_LOC655919.1.1,,,,,,,KCNT1_MOUSE,Mus musculus (Mouse), comp74176_c0_seq1,209,66.0287,0.90519314,0,18,,3.00E-42,Q6AB49,tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase),tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase),GO:0005524; GO:0005737; GO:0016879; GO:0006400,"ATP binding; cytoplasm; ligase activity, forming carbon-nitrogen bonds; tRNA modification",PF01171;,,,,,,,,,TILS_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),tRNA modification [GO:0006400] comp74185_c0_seq1,444,43.2432,0.63210548,7,15,,2.00E-11,A2ASS6,Titin (EC 2.7.11.1) (Connectin),Titin (EC 2.7.11.1) (Connectin),GO:0005524; GO:0031430; GO:0030018; GO:0007512; GO:0055003; GO:0043056; GO:0003007; GO:0001701; GO:0046872; GO:0006936; GO:0005859; GO:0005634; GO:0018108; GO:0004674; GO:0004713; GO:1901897; GO:0045214; GO:0001756; GO:0005200,ATP binding; M band; Z disc; adult heart development; cardiac myofibril assembly; forward locomotion; heart morphogenesis; in utero embryonic development; metal ion binding; muscle contraction; muscle myosin complex; nucleus; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of relaxation of cardiac muscle; sarcomere organization; somitogenesis; structural constituent of cytoskeleton,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_MOUSE,Mus musculus (Mouse),adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591] comp74215_c0_seq1,221,44.3439,1.03828656,1,8,,1.00E-21,B1MTL0,Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Solute carrier family 4 member 3),Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Solute carrier family 4 member 3),GO:0005452; GO:0016021,inorganic anion exchanger activity; integral to membrane,PF07565;PF00955;,8.00E-35,CHOYP_S4A10.3.4,,,,,,,B3A3_CALMO,Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch), comp74218_c0_seq1,356,42.1348,0.70125553,9,4,,1.00E-44,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,7.00E-70,CHOYP_DNAH5.2.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp74252_c0_seq1,294,44.2177,0.77465685,3,7,,2.00E-25,Q5F3I6,Transmembrane protein 104,Transmembrane protein 104,GO:0016021,integral to membrane,PF01490;,,,,,,,,,TM104_CHICK,Gallus gallus (Chicken), comp74274_c0_seq1,337,42.1365,0.33854465,3,14,,9.00E-22,P46635,Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese),GO:0008097; GO:0005759; GO:0035928; GO:0004792,5S rRNA binding; mitochondrial matrix; rRNA import into mitochondrion; thiosulfate sulfurtransferase activity,PF00581;,,,7.00E-17,ruditapes_c9218,,,,,THTR_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029] comp74281_c0_seq1,338,42.0118,0.27093144,6,8,,7.00E-12,Q9BQ50,Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2),Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2),GO:0008296; GO:0006281; GO:0008853; GO:0000287; GO:0003676; GO:0005634,3'-5'-exodeoxyribonuclease activity; DNA repair; exodeoxyribonuclease III activity; magnesium ion binding; nucleic acid binding; nucleus,,,,,,,,,,TREX2_HUMAN,Homo sapiens (Human),DNA metabolic process [GO:0006259]; DNA repair [GO:0006281] comp74285_c0_seq1,359,47.3538,0.72664924,6,6,,6.00E-30,Q810B6,Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif),Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif),GO:0006897; GO:0010008; GO:0046872,endocytosis; endosome membrane; metal ion binding,PF00023;PF12796;PF00651;PF01363;,2.00E-39,CHOYP_LOC100372945.1.2,,,,,,,ANFY1_MOUSE,Mus musculus (Mouse),"endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" comp74285_c1_seq1,266,40.2256,0.47577294,1,20,,1.00E-06,B7U179,ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1),ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1),GO:0031261; GO:0006261; GO:2000104; GO:0008285; GO:0016567,DNA replication preinitiation complex; DNA-dependent DNA replication; negative regulation of DNA-dependent DNA replication; negative regulation of cell proliferation; protein ubiquitination,PF00514;PF00651;,3.00E-34,CHOYP_LOC100372945.2.2,,,,,,,ABAP1_ARATH,Arabidopsis thaliana (Mouse-ear cress),DNA-dependent DNA replication [GO:0006261]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA-dependent DNA replication [GO:2000104]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127] comp74304_c0_seq1,246,48.374,0.58845523,4,0,,6.00E-20,Q4R5L5,Annexin A7 (Annexin VII) (Annexin-7),Annexin A7 (Annexin VII) (Annexin-7),GO:0005509; GO:0005544,calcium ion binding; calcium-dependent phospholipid binding,PF00191;,,,,,,,,,ANXA7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp74344_c0_seq1,886,42.3251,0.28507604,11,12,,7.00E-17,Q5UQ88,Probable ubiquitin-conjugating enzyme E2 R521 (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),Probable ubiquitin-conjugating enzyme E2 R521 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R521) (Ubiquitin carrier protein) (Ubiquitin-protein ligase),GO:0005524; GO:0042262; GO:0016021; GO:0004842,ATP binding; DNA protection; integral to membrane; ubiquitin-protein ligase activity,PF00179;,2.00E-43,CHOYP_BRAFLDRAFT_85147.1.1,,,,,,,UBC3_MIMIV,Acanthamoeba polyphaga mimivirus (APMV),protein ubiquitination [GO:0016567] comp74344_c0_seq2,633,41.3902,0.26304001,3,5,,,,,,,,,1.00E-38,CHOYP_BRAFLDRAFT_85147.1.1,,,,,,,,, comp74384_c0_seq1,218,46.3303,0.52393447,2,3,,2.00E-07,Q27757,Luciferin 4-monooxygenase (Luciferase) (EC 1.13.12.7),Luciferin 4-monooxygenase (Luciferase) (EC 1.13.12.7),GO:0005524; GO:0047077; GO:0008218; GO:0046872; GO:0005777,ATP binding; Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity; bioluminescence; metal ion binding; peroxisome,PF00501;PF13193;,,,,,,,,,LUCI_PHOPE,Photuris pensylvanica (Pennsylania firefly),bioluminescence [GO:0008218] comp74385_c0_seq1,216,46.7593,1.11504366,2,7,,7.00E-18,P10155,60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2),60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2),GO:0003723; GO:0060271; GO:0005737; GO:0046872; GO:0005634; GO:0030529; GO:0006383,RNA binding; cilium morphogenesis; cytoplasm; metal ion binding; nucleus; ribonucleoprotein complex; transcription from RNA polymerase III promoter,PF05731;,,,8.00E-26,ruditapes_c1148,,,,,RO60_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]; transcription from RNA polymerase III promoter [GO:0006383] comp7440_c0_seq1,255,44.7059,0.32979573,4,0,,5.00E-25,P47990,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0030151; GO:0043546; GO:0005777; GO:0034418; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; peroxisome; urate biosynthetic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,9.00E-16,CHOYP_XDH.2.3,,,,,,,XDH_CHICK,Gallus gallus (Chicken),urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] comp74413_c0_seq1,417,44.8441,0.47980074,12,12,,2.00E-37,Q8CI15,Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91),Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91),GO:0005524; GO:0017050; GO:0003677; GO:0003951; GO:0001568; GO:0007420; GO:0019722; GO:0005516; GO:0005737; GO:0004143; GO:0006954; GO:0000287; GO:0005634; GO:0005886; GO:0042346; GO:0051092; GO:0045766; GO:0030307; GO:0030335; GO:0008284; GO:0048146; GO:0045931; GO:0031398; GO:0045987; GO:0007205; GO:0032651; GO:0010803; GO:0008481; GO:0006670,ATP binding; D-erythro-sphingosine kinase activity; DNA binding; NAD+ kinase activity; blood vessel development; brain development; calcium-mediated signaling; calmodulin binding; cytoplasm; diacylglycerol kinase activity; inflammatory response; magnesium ion binding; nucleus; plasma membrane; positive regulation of NF-kappaB import into nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of angiogenesis; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of fibroblast proliferation; positive regulation of mitotic cell cycle; positive regulation of protein ubiquitination; positive regulation of smooth muscle contraction; protein kinase C-activating G-protein coupled receptor signaling pathway; regulation of interleukin-1 beta production; regulation of tumor necrosis factor-mediated signaling pathway; sphinganine kinase activity; sphingosine metabolic process,PF00781;,,,,,,,,,SPHK1_MOUSE,Mus musculus (Mouse),blood vessel development [GO:0001568]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of interleukin-1 beta production [GO:0032651]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to amine [GO:0014075]; response to ATP [GO:0033198]; response to interleukin-1 [GO:0070555]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; sphingosine biosynthetic process [GO:0046512]; sphingosine metabolic process [GO:0006670] comp74427_c0_seq1,237,45.1477,0.92445149,5,7,,2.00E-12,Q8TEK3,"Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)","Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)",GO:0003677; GO:0018024; GO:0005634; GO:0046425; GO:2000677,DNA binding; histone-lysine N-methyltransferase activity; nucleus; regulation of JAK-STAT cascade; regulation of transcription regulatory region DNA binding,PF08123;,3.00E-21,CHOYP_PABP4.2.6,,,,,,,DOT1L_HUMAN,Homo sapiens (Human),chromatin silencing [GO:0006342]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200] comp74435_c0_seq1,266,43.985,0.86689537,2,9,,3.00E-51,P00414,Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III),Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III),GO:0019646; GO:0004129; GO:0016021; GO:0006123; GO:0005743; GO:0045277; GO:0008535; GO:0044281,"aerobic electron transport chain; cytochrome-c oxidase activity; integral to membrane; mitochondrial electron transport, cytochrome c to oxygen; mitochondrial inner membrane; respiratory chain complex IV; respiratory chain complex IV assembly; small molecule metabolic process",PF00510;,3.00E-54,CHOYP_COX3.1.3,,,,,,,COX3_HUMAN,Homo sapiens (Human),"aerobic electron transport chain [GO:0019646]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; respiratory chain complex IV assembly [GO:0008535]" comp74437_c0_seq1,381,48.0315,0.41342276,10,4,,8.00E-18,Q12923,Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1),Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1),GO:0005737; GO:0005856; GO:0030027; GO:0005634; GO:0005886; GO:0004725,cytoplasm; cytoskeleton; lamellipodium; nucleus; plasma membrane; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00595;PF00102;,,,,,,,,,PTN13_HUMAN,Homo sapiens (Human),peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] comp7444_c0_seq1,224,37.9464,0.95456448,5,13,,5.00E-13,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,7.00E-17,CHOYP_LOC100372741.2.3,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp74487_c0_seq1,324,45.9877,0.6490621,7,0,,7.00E-18,Q9UMZ2,Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin),Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin),GO:0030121; GO:0005509; GO:0006897; GO:0006886,AP-1 adaptor complex; calcium ion binding; endocytosis; intracellular protein transport,,,,,,,,,,SYNRG_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] comp74490_c1_seq1,304,45.0658,0.35697952,4,42,,3.00E-13,A0JND9,Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5),Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5),GO:0005524; GO:0016787; GO:0016021; GO:0046872; GO:0005886,ATP binding; hydrolase activity; integral to membrane; metal ion binding; plasma membrane,PF01150;,,,,,,,,,ENTP8_BOVIN,Bos taurus (Bovine), comp74500_c0_seq2,552,35.5072,0.23836285,3,0,,8.00E-11,P31843,RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog),RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog),GO:0003723; GO:0006278; GO:0003964; GO:0003968; GO:0005739,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; RNA-directed RNA polymerase activity; mitochondrion,PF00078;,5.00E-11,CHOYP_contig_014865,,,,,,,RRPO_OENBE,Oenothera berteroana (Bertero's evening primrose), comp74506_c0_seq1,274,60.9489,0.98780051,4,14,,4.00E-34,Q6A6N1,50S ribosomal protein L22,50S ribosomal protein L22,GO:0015934; GO:0019843; GO:0003735; GO:0006412,large ribosomal subunit; rRNA binding; structural constituent of ribosome; translation,PF00237;,,,,,,,,,RL22_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),translation [GO:0006412] comp74507_c0_seq1,455,41.7582,0.60962861,13,6,,1.00E-13,Q60636,PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1),GO:0003677; GO:0045165; GO:0005737; GO:0042462; GO:0007281; GO:0042826; GO:0001893; GO:0046872; GO:0008168; GO:0007275; GO:0030889; GO:0031665; GO:0000122; GO:0005634; GO:0045579; GO:0010628; GO:0006355; GO:0043565; GO:0006351; GO:0060707,"DNA binding; cell fate commitment; cytoplasm; eye photoreceptor cell development; germ cell development; histone deacetylase binding; maternal placenta development; metal ion binding; methyltransferase activity; multicellular organismal development; negative regulation of B cell proliferation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of B cell differentiation; positive regulation of gene expression; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent; trophoblast giant cell differentiation",PF00856;PF13912;,,,,,,,,,PRDM1_MOUSE,Mus musculus (Mouse),"aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]" comp74512_c1_seq1,241,41.0788,0.59314747,8,0,,7.00E-37,Q658Y4,Protein FAM91A1,Protein FAM91A1,,,PF14648;PF14647;,1.00E-46,CHOYP_F91A1.1.1,,,,,,,F91A1_HUMAN,Homo sapiens (Human), comp74528_c0_seq1,488,36.4754,0.37342654,19,9,,7.00E-33,Q5R5J6,Gamma-tubulin complex component 2 (GCP-2),Gamma-tubulin complex component 2 (GCP-2),GO:0005737; GO:0005874; GO:0000226; GO:0005815; GO:0000922,cytoplasm; microtubule; microtubule cytoskeleton organization; microtubule organizing center; spindle pole,PF04130;,8.00E-33,CHOYP_GCP2.1.1,,,,,,,GCP2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),microtubule nucleation [GO:0007020] comp74534_c0_seq1,622,44.2122,0.26462848,21,4,,8.00E-64,Q0KK59,Protein unc-79 homolog,Protein unc-79 homolog,GO:0048149; GO:0016021; GO:0035264,behavioral response to ethanol; integral to membrane; multicellular organism growth,,4.00E-95,CHOYP_UNC79.2.4,,,,,,,UNC79_MOUSE,Mus musculus (Mouse),adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] comp74535_c1_seq1,384,44.0104,1.33334238,2,38,,1.00E-10,P04916,Retinol-binding protein 4 (Plasma retinol-binding protein) (PRBP) (RBP),Retinol-binding protein 4 (Plasma retinol-binding protein) (PRBP) (RBP),GO:0048738; GO:0048562; GO:0060059; GO:0048706; GO:0005615; GO:0048807; GO:0006094; GO:0042593; GO:0060347; GO:0030324; GO:0030277; GO:0060044; GO:0051024; GO:0032024; GO:0043234; GO:0046982; GO:0045471; GO:0032526; GO:0016918; GO:0019841; GO:0042572; GO:0034632; GO:0060157; GO:0060065; GO:0060068,cardiac muscle tissue development; embryonic organ morphogenesis; embryonic retina morphogenesis in camera-type eye; embryonic skeletal system development; extracellular space; female genitalia morphogenesis; gluconeogenesis; glucose homeostasis; heart trabecula formation; lung development; maintenance of gastrointestinal epithelium; negative regulation of cardiac muscle cell proliferation; positive regulation of immunoglobulin secretion; positive regulation of insulin secretion; protein complex; protein heterodimerization activity; response to ethanol; response to retinoic acid; retinal binding; retinol binding; retinol metabolic process; retinol transporter activity; urinary bladder development; uterus development; vagina development,PF00061;,,,6.00E-31,ruditapes_c4025,,,,,RET4_RAT,Rattus norvegicus (Rat),eye development [GO:0001654]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; maintenance of gastrointestinal epithelium [GO:0030277]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; transport [GO:0006810] comp74559_c0_seq1,608,38.6513,1.32353299,4,85,,,,,,,,,,,2.00E-20,ruditapes_c13703,,,,,,, comp74583_c0_seq1,268,47.0149,0.94982407,1,8,,1.00E-19,Q3YIX4,Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)],Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)],GO:0005524; GO:0005737; GO:0008289; GO:0004867,ATP binding; cytoplasm; lipid binding; serine-type endopeptidase inhibitor activity,PF01161;,,,,,,,,,PEBP1_CANFA,Canis lupus familiaris (Dog) (Canis familiaris), comp74616_c0_seq1,260,38.8462,0.62441115,7,2,,8.00E-29,Q6DFF9,Mitogen-activated protein kinase-binding protein 1,Mitogen-activated protein kinase-binding protein 1,,,PF00400;,3.00E-15,CHOYP_MABP1.2.2,,,,,,,MABP1_XENLA,Xenopus laevis (African clawed frog), comp74631_c0_seq1,289,43.2526,0.38198561,3,19,,5.00E-10,Q5SYL3,UPF0378 protein KIAA0100,Protein KIAA0100,GO:0005576,extracellular region,PF10351;PF10344;PF10347;,,,,,,,,,K0100_MOUSE,Mus musculus (Mouse), comp74664_c0_seq1,710,41.1268,0.50035286,10,20,,9.00E-07,Q4G017,Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline-1 receptor) (I1R),Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline-1 receptor) (I1R),GO:0008227; GO:0006915; GO:0005829; GO:0005769; GO:0006006; GO:0016020; GO:0048243; GO:0035091; GO:0005886; GO:0055037; GO:0008217; GO:0032228,"G-protein coupled amine receptor activity; apoptotic process; cytosol; early endosome; glucose metabolic process; membrane; norepinephrine secretion; phosphatidylinositol binding; plasma membrane; recycling endosome; regulation of blood pressure; regulation of synaptic transmission, GABAergic",PF00787;,1.00E-12,CHOYP_NISCH.1.2,,,,,,,NISCH_RAT,Rattus norvegicus (Rat),"actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]" comp74672_c0_seq1,233,45.9227,0.86476094,7,0,,4.00E-36,A7SG73,Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (Fragment),Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (Fragment),GO:0009435; GO:0004514,NAD biosynthetic process; nicotinate-nucleotide diphosphorylase (carboxylating) activity,PF01729;PF02749;,2.00E-35,CHOYP_BRAFLDRAFT_232705.1.2,,,,,,,NADC_NEMVE,Nematostella vectensis (Starlet sea anemone),NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213] comp74702_c0_seq1,350,44.2857,0.242238,3,48,,9.00E-06,Q01082,"Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)","Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)",GO:0043001; GO:0031430; GO:0007184; GO:0003779; GO:0051693; GO:0030506; GO:0030673; GO:0007411; GO:0007182; GO:0032437; GO:0005829; GO:0071709; GO:0000281; GO:0005730; GO:0005543; GO:0072661; GO:0008091; GO:0014731; GO:0005200,Golgi to plasma membrane protein transport; M band; SMAD protein import into nucleus; actin binding; actin filament capping; ankyrin binding; axolemma; axon guidance; common-partner SMAD protein phosphorylation; cuticular plate; cytosol; membrane assembly; mitotic cytokinesis; nucleolus; phospholipid binding; protein targeting to plasma membrane; spectrin; spectrin-associated cytoskeleton; structural constituent of cytoskeleton,PF00307;PF00435;,,,,,,,,,SPTB2_HUMAN,Homo sapiens (Human),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184] comp74737_c0_seq1,377,40.3183,0.67416205,14,8,,2.00E-53,Q5R573,Rab-like protein 2A,Rab-like protein 2A,GO:0005525; GO:0007264,GTP binding; small GTPase mediated signal transduction,PF00071;,6.00E-52,CHOYP_LOC100371074.1.1,,,,,,,RBL2A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),small GTPase mediated signal transduction [GO:0007264] comp74761_c1_seq1,312,39.4231,0.74722253,8,13,,2.00E-19,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,,,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp74781_c0_seq1,401,47.1322,0.49552079,18,10,,,,,,,,,8.00E-57,CHOYP_MROH1.1.1,,,,,,,,, comp74781_c1_seq2,436,44.9541,0.27870045,7,4,,1.00E-41,A7E2Y6,Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A),,,,,,,,,,,,HRT7A_BOVIN,Bos taurus (Bovine), comp74783_c0_seq1,854,43.6768,0.24882171,14,55,,2.00E-40,O60287,Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog),Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog),GO:0005730,nucleolus,PF16201;PF11707;,,,,,,,,,NPA1P_HUMAN,Homo sapiens (Human), comp7478_c0_seq1,266,36.4662,1.25514594,5,5,,,,,,,,,,,3.00E-13,ruditapes_c8935,,,,,,, comp74792_c0_seq1,354,44.6328,0.28482256,11,7,,9.00E-36,Q14155,Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85),Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85),GO:0005089; GO:0097190; GO:0005938; GO:0005829; GO:0007173; GO:0005925; GO:0005085; GO:0030027; GO:0030032; GO:0042059; GO:0007399; GO:0043005; GO:0043025; GO:0048011; GO:0005543; GO:0043547; GO:0043065; GO:0043234; GO:0035023; GO:0051056; GO:0001726; GO:0007264,Rho guanyl-nucleotide exchange factor activity; apoptotic signaling pathway; cell cortex; cytosol; epidermal growth factor receptor signaling pathway; focal adhesion; guanyl-nucleotide exchange factor activity; lamellipodium; lamellipodium assembly; negative regulation of epidermal growth factor receptor signaling pathway; nervous system development; neuron projection; neuronal cell body; neurotrophin TRK receptor signaling pathway; phospholipid binding; positive regulation of GTPase activity; positive regulation of apoptotic process; protein complex; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; ruffle; small GTPase mediated signal transduction,PF00307;PF00169;PF00621;PF07653;,4.00E-16,CHOYP_ARHG7.1.5,,,,,,,ARHG7_HUMAN,Homo sapiens (Human),ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of protein binding [GO:0032092]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp74793_c0_seq1,214,63.5514,1.00268678,1,0,,3.00E-29,Q6AAP6,Cobyric acid synthase,Cobyric acid synthase,GO:0009236; GO:0015420; GO:0006541,cobalamin biosynthetic process; cobalamin-transporting ATPase activity; glutamine metabolic process,PF01656;PF07685;,,,,,,,,,COBQ_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cobalamin biosynthetic process [GO:0009236]; glutamine metabolic process [GO:0006541] comp74797_c0_seq1,537,46.9274,0.34311343,10,8,,4.00E-13,Q9NSC2,Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1),GO:0003677; GO:0016581; GO:0030325; GO:0008013; GO:0001658; GO:0003682; GO:0010369; GO:0005737; GO:0048566; GO:0042733; GO:0035136; GO:0008406; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:0045879; GO:0000122; GO:0001843; GO:0005634; GO:0021889; GO:0061034; GO:0021553; GO:0042473; GO:0021983; GO:0030177; GO:0045666; GO:0045944; GO:2000177; GO:0003700; GO:0006351; GO:0072092; GO:0003281,"DNA binding; NuRD complex; adrenal gland development; beta-catenin binding; branching involved in ureteric bud morphogenesis; chromatin binding; chromocenter; cytoplasm; embryonic digestive tract development; embryonic digit morphogenesis; forelimb morphogenesis; gonad development; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; nucleus; olfactory bulb interneuron differentiation; olfactory bulb mitral cell layer development; olfactory nerve development; outer ear morphogenesis; pituitary gland development; positive regulation of Wnt receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of neural precursor cell proliferation; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; ureteric bud invasion; ventricular septum development",PF00096;,,,,,,,,,SALL1_HUMAN,Homo sapiens (Human),"adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp74809_c0_seq1,314,70.0637,1.0673662,0,24,,2.00E-25,P23484,Probable RNA polymerase sigma factor FecI,Probable RNA polymerase sigma factor FecI,GO:0003677; GO:0006352; GO:0006811; GO:0055072; GO:0003700; GO:0016987,"DNA binding; DNA-dependent transcription, initiation; ion transport; iron ion homeostasis; sequence-specific DNA binding transcription factor activity; sigma factor activity",PF04542;PF08281;,,,,,,,,,FECI_ECOLI,Escherichia coli (strain K12),"DNA-templated transcription, initiation [GO:0006352]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]" comp74811_c0_seq1,704,40.625,0.44827677,0,0,,6.00E-12,P52429,Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon),Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon),GO:0005524; GO:0003951; GO:0005737; GO:0004143; GO:0016021; GO:0035556; GO:0046872; GO:0008654; GO:0005886; GO:0030168; GO:0007205,ATP binding; NAD+ kinase activity; cytoplasm; diacylglycerol kinase activity; integral to membrane; intracellular signal transduction; metal ion binding; phospholipid biosynthetic process; plasma membrane; platelet activation; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF00609;PF00781;,,,,,,,,,DGKE_HUMAN,Homo sapiens (Human),intracellular signal transduction [GO:0035556]; phospholipid biosynthetic process [GO:0008654]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205] comp74811_c0_seq2,680,41.4706,0.44550217,0,0,,5.00E-48,Q01583,Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107),GO:0005524; GO:0003951; GO:0005509; GO:0004143; GO:0035556; GO:0007205,ATP binding; NAD+ kinase activity; calcium ion binding; diacylglycerol kinase activity; intracellular signal transduction; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00130;PF14513;PF00609;PF00781;,1.00E-64,CHOYP_DGKB.1.1,,,,,,,DGK1_DROME,Drosophila melanogaster (Fruit fly),intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313] comp74818_c0_seq1,250,38,0.44902328,3,18,,2.00E-08,P28665,Murinoglobulin-1 (MuG1),Murinoglobulin-1 (MuG1),GO:0007566; GO:0005615; GO:0010951; GO:0004867,embryo implantation; extracellular space; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,MUG1_MOUSE,Mus musculus (Mouse),embryo implantation [GO:0007566] comp74831_c0_seq1,252,41.2698,0.09583484,6,20,,3.00E-29,O08811,TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein),TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein),GO:0051539; GO:0043139; GO:0005524; GO:0004003; GO:0003677; GO:0071817; GO:0008353; GO:0009650; GO:0007568; GO:0006915; GO:0030282; GO:0000075; GO:0008283; GO:0032289; GO:0007059; GO:0019907; GO:0005737; GO:0040016; GO:0043249; GO:0030198; GO:0035315; GO:0048820; GO:0060218; GO:0005675; GO:0001701; GO:0046872; GO:0035264; GO:0033683; GO:0043388; GO:0045944; GO:0009791; GO:0006979; GO:0021510; GO:0006366; GO:0006283,"4 iron, 4 sulfur cluster binding; 5'-3' DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; DNA binding; MMXD complex; RNA polymerase II carboxy-terminal domain kinase activity; UV protection; aging; apoptotic process; bone mineralization; cell cycle checkpoint; cell proliferation; central nervous system myelin formation; chromosome segregation; cyclin-dependent protein kinase activating kinase holoenzyme complex; cytoplasm; embryonic cleavage; erythrocyte maturation; extracellular matrix organization; hair cell differentiation; hair follicle maturation; hematopoietic stem cell differentiation; holo TFIIH complex; in utero embryonic development; metal ion binding; multicellular organism growth; nucleotide-excision repair, DNA incision; positive regulation of DNA binding; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; response to oxidative stress; spinal cord development; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF06733;PF06777;PF13307;,5.00E-44,CHOYP_ERCC2.1.1,,,,,,,ERCC2_MOUSE,Mus musculus (Mouse),"aging [GO:0007568]; apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; cell proliferation [GO:0008283]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair cycle process [GO:0022405]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; skin development [GO:0043588]; spinal cord development [GO:0021510]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; UV protection [GO:0009650]" comp74838_c1_seq1,223,41.2556,1.06062739,0,31,,7.00E-13,Q5GIG6,Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (TNNI3-interacting kinase),Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (TNNI3-interacting kinase),GO:0005524; GO:0005737; GO:0046872; GO:0005634; GO:0004674,ATP binding; cytoplasm; metal ion binding; nucleus; protein serine/threonine kinase activity,PF00023;PF12796;PF07714;,,,,,,,,,TNI3K_MOUSE,Mus musculus (Mouse),bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027] comp74881_c0_seq1,320,59.0625,0.88349487,3,21,,3.00E-27,P18275,Arginine/ornithine antiporter,Arginine/ornithine antiporter,GO:0006527; GO:0043858; GO:0006520; GO:0005887; GO:0016020; GO:0006810,arginine catabolic process; arginine:ornithine antiporter activity; cellular amino acid metabolic process; integral to plasma membrane; membrane; transport,PF13520;,,,,,,,,,ARCD_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),arginine deiminase pathway [GO:0019546] comp74896_c0_seq1,231,44.5887,0.80931749,5,11,,2.00E-13,Q03567,Uncharacterized transporter C38C10.2,Uncharacterized transporter slc-17.2,GO:0016021; GO:0006814; GO:0015293,integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,YLD2_CAEEL,Caenorhabditis elegans,anion transport [GO:0006820]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085] comp74913_c1_seq1,334,38.6228,0.81350899,6,5,,5.00E-33,P98999,Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (xlAC),Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (xlAC),GO:0005524; GO:0004016; GO:0016021; GO:0035556; GO:0046872,ATP binding; adenylate cyclase activity; integral to membrane; intracellular signal transduction; metal ion binding,PF00211;,4.00E-41,CHOYP_APLD.1.1,,,,,,,ADCY9_XENLA,Xenopus laevis (African clawed frog),adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556] comp74928_c0_seq1,244,46.7213,0.45245451,4,0,,3.00E-15,Q6P2B1,Transportin-3,Transportin-3,GO:0005737; GO:0005634; GO:0035048,cytoplasm; nucleus; splicing factor protein import into nucleus,PF08389;,,,,,,,,,TNPO3_MOUSE,Mus musculus (Mouse),protein import into nucleus [GO:0006606]; splicing factor protein import into nucleus [GO:0035048] comp74975_c0_seq1,217,59.9078,1.13759532,0,23,,4.00E-13,P0C0V0,Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do),Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do),GO:0006515; GO:0030288; GO:0005886; GO:0006457; GO:0006979; GO:0009266; GO:0004252,misfolded or incompletely synthesized protein catabolic process; outer membrane-bounded periplasmic space; plasma membrane; protein folding; response to oxidative stress; response to temperature stimulus; serine-type endopeptidase activity,PF00595;,,,,,,,,,DEGP_ECOLI,Escherichia coli (strain K12),misfolded or incompletely synthesized protein catabolic process [GO:0006515]; protein folding [GO:0006457]; proteolysis [GO:0006508]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266] comp74995_c1_seq1,351,43.0199,0.5667309,0,34,,4.00E-09,Q63276,Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Kan-1) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Kan-1) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2),GO:0016410; GO:0006637; GO:0006699; GO:0002152; GO:0004091; GO:0005829; GO:0006631; GO:0047963; GO:0006544; GO:0001889; GO:0052815; GO:0031100; GO:0016290; GO:0005777; GO:0019530; GO:0052817,N-acyltransferase activity; acyl-CoA metabolic process; bile acid biosynthetic process; bile acid conjugation; carboxylesterase activity; cytosol; fatty acid metabolic process; glycine N-choloyltransferase activity; glycine metabolic process; liver development; medium-chain acyl-CoA hydrolase activity; organ regeneration; palmitoyl-CoA hydrolase activity; peroxisome; taurine metabolic process; very long chain acyl-CoA hydrolase activity,PF08840;PF04775;,,,,,,,,,BAAT_RAT,Rattus norvegicus (Rat),acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530] comp75017_c1_seq1,537,44.1341,0.59069155,14,0,,8.00E-21,Q6P3V7,Tetratricopeptide repeat protein GNN (TPR repeat protein GNN) (Grp94-neighboring nucleotidase),Tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase),GO:0005737,cytoplasm,,,,,,,,,,GNN_RAT,Rattus norvegicus (Rat), comp75033_c0_seq1,315,42.5397,0.35585944,14,15,,7.00E-09,P82596,Perlucin,Perlucin,GO:0030246,carbohydrate binding,PF00059;,,,,,,,,,PLC_HALLA,Haliotis laevigata (Abalone), comp75046_c0_seq1,228,50.4386,0.97035765,9,9,,8.00E-06,Q14644,Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein),Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein),GO:0005099; GO:0015278; GO:0005737; GO:0035556; GO:0031235; GO:0046872; GO:0046580; GO:0005543; GO:0007165,Ras GTPase activator activity; calcium-release channel activity; cytoplasm; intracellular signal transduction; intrinsic to internal side of plasma membrane; metal ion binding; negative regulation of Ras protein signal transduction; phospholipid binding; signal transduction,PF00779;PF00168;PF00169;PF00616;,,,,,,,,,RASA3_HUMAN,Homo sapiens (Human),MAPK cascade [GO:0000165]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165] comp75063_c0_seq1,232,46.5517,0.3197315,3,20,,,,,,,,,7.00E-23,CHOYP_NEMVEDRAFT_V1G197267.1.1,,,,,,,,, comp75071_c0_seq1,246,47.9675,0.63880366,0,16,,3.00E-11,Q90953,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp75071_c1_seq1,428,44.8598,0.6638701,2,17,,5.00E-23,P10040,Protein crumbs (95F),Protein crumbs (95F),GO:0016324; GO:0016327; GO:0005509; GO:0061336; GO:0046664; GO:0045198; GO:0016332; GO:0016334; GO:0016021; GO:0035002; GO:0035090; GO:0061024; GO:0045746; GO:0046621; GO:0048477; GO:0045494; GO:0008284; GO:0042327; GO:0008104; GO:0035330; GO:0045570; GO:0016028; GO:0042052; GO:0007435; GO:0005918; GO:0030507; GO:0035003; GO:0045186; GO:0045218,"apical plasma membrane; apicolateral plasma membrane; calcium ion binding; cell morphogenesis involved in Malpighian tubule morphogenesis; dorsal closure, amnioserosa morphology change; establishment of epithelial cell apical/basal polarity; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of polarity of follicular epithelium; integral to membrane; liquid clearance, open tracheal system; maintenance of apical/basal cell polarity; membrane organization; negative regulation of Notch signaling pathway; negative regulation of organ growth; oogenesis; photoreceptor cell maintenance; positive regulation of cell proliferation; positive regulation of phosphorylation; protein localization; regulation of hippo signaling cascade; regulation of imaginal disc growth; rhabdomere; rhabdomere development; salivary gland morphogenesis; septate junction; spectrin binding; subapical complex; zonula adherens assembly; zonula adherens maintenance",PF00008;PF07645;PF00054;PF02210;,,,,,,,,,CRB_DROME,Drosophila melanogaster (Fruit fly),"adherens junction organization [GO:0034332]; cell-cell junction assembly [GO:0007043]; cell morphogenesis involved in Malpighian tubule morphogenesis [GO:0061336]; centrosome localization [GO:0051642]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor development [GO:0042051]; dorsal closure, amnioserosa morphology change [GO:0046664]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; liquid clearance, open tracheal system [GO:0035002]; maintenance of apical/basal cell polarity [GO:0035090]; Malpighian tubule morphogenesis [GO:0007443]; membrane organization [GO:0061024]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of organ growth [GO:0046621]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nuclear chromosome segregation [GO:0098813]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphorylation [GO:0042327]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of hippo signaling [GO:0035330]; regulation of imaginal disc growth [GO:0045570]; regulation of intracellular protein transport [GO:0033157]; regulation of protein localization [GO:0032880]; rhabdomere development [GO:0042052]; rhabdomere morphogenesis [GO:0061541]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; tube morphogenesis [GO:0035239]; zonula adherens assembly [GO:0045186]; zonula adherens maintenance [GO:0045218]" comp75081_c0_seq1,233,42.0601,0.48811913,5,0,,6.00E-07,Q9UBS8,E3 ubiquitin-protein ligase RNF14 (EC 6.3.2.-) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) (Triad2 protein),E3 ubiquitin-protein ligase RNF14 (EC 6.3.2.-) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) (Triad2 protein),GO:0030521; GO:0005737; GO:0005634; GO:0045893; GO:0016567; GO:0060765; GO:0006357; GO:0032355; GO:0019787; GO:0003713; GO:0006351; GO:0008270,"androgen receptor signaling pathway; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; protein ubiquitination; regulation of androgen receptor signaling pathway; regulation of transcription from RNA polymerase II promoter; response to estradiol stimulus; small conjugating protein ligase activity; transcription coactivator activity; transcription, DNA-dependent; zinc ion binding",PF01485;PF05773;,,,,,,,,,RNF14_HUMAN,Homo sapiens (Human),"androgen receptor signaling pathway [GO:0030521]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription, DNA-templated [GO:0045893]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp75100_c0_seq1,201,45.7711,0.20750385,5,6,,,,,,,,,1.00E-19,CHOYP_contig_039575,3.00E-12,ruditapes_c3910,,,,,,, comp75102_c0_seq1,276,40.942,0.79497217,6,2,,3.00E-13,Q9NXG6,Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4),GO:0031418; GO:0005509; GO:0005789; GO:0016021; GO:0005506; GO:0016706,"L-ascorbic acid binding; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",PF13640;PF13499;,,,,,,,,,P4HTM_HUMAN,Homo sapiens (Human),regulation of erythrocyte differentiation [GO:0045646] comp75121_c0_seq1,341,44.868,0.52705933,3,45,,2.00E-06,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp75126_c0_seq1,857,49.0082,0.37961117,18,0,,6.00E-59,Q8TEQ6,Gem-associated protein 5 (Gemin5),Gem-associated protein 5 (Gemin5),GO:0097504; GO:0005829; GO:0034660; GO:0016604; GO:0006461; GO:0017069; GO:0005681; GO:0000387,Gemini of coiled bodies; cytosol; ncRNA metabolic process; nuclear body; protein complex assembly; snRNA binding; spliceosomal complex; spliceosomal snRNP assembly,PF12894;PF00400;,,,,,,,,,GEMI5_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; protein complex assembly [GO:0006461]; spliceosomal snRNP assembly [GO:0000387]" comp75189_c0_seq1,211,47.8673,0.93506511,3,0,,2.00E-29,P15541,Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0005886; GO:0006508; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; plasma membrane; proteolysis; zinc ion binding,PF11838;PF01433;,1.00E-18,CHOYP_LOC409619.3.4,,,,,,,AMPN_RABIT,Oryctolagus cuniculus (Rabbit),angiogenesis [GO:0001525]; cell differentiation [GO:0030154] comp75217_c0_seq1,357,36.6947,1.26831416,16,0,,1.00E-10,Q13183,Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter),GO:0005887; GO:0015361,integral to plasma membrane; low affinity sodium:dicarboxylate symporter activity,PF00939;,,,,,,,,,S13A2_HUMAN,Homo sapiens (Human),transport [GO:0006810] comp7521_c0_seq1,212,50,0.45758268,4,0,,2.00E-19,Q14432,"cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)","cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)",GO:0004115; GO:0007596; GO:0030552; GO:0006198; GO:0019933; GO:0004119; GO:0019934; GO:0071321; GO:0071560; GO:0005829; GO:0016101; GO:0016021; GO:0006629; GO:0046872; GO:0043066; GO:0043116; GO:0001556; GO:0060282; GO:0043117; GO:0040020; GO:0051591; GO:0042493,"3',5'-cyclic-AMP phosphodiesterase activity; blood coagulation; cAMP binding; cAMP catabolic process; cAMP-mediated signaling; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; cGMP-mediated signaling; cellular response to cGMP; cellular response to transforming growth factor beta stimulus; cytosol; diterpenoid metabolic process; integral to membrane; lipid metabolic process; metal ion binding; negative regulation of apoptotic process; negative regulation of vascular permeability; oocyte maturation; positive regulation of oocyte development; positive regulation of vascular permeability; regulation of meiosis; response to cAMP; response to drug",PF00233;,2.00E-22,CHOYP_PDE3A.3.3,,,,,,,PDE3A_HUMAN,Homo sapiens (Human),cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; diterpenoid metabolic process [GO:0016101]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; response to cAMP [GO:0051591]; response to drug [GO:0042493] comp75248_c0_seq1,210,45.2381,0.66713347,3,2,,6.00E-15,Q94KD8,Probable beta-D-xylosidase 2 (AtBXL2) (EC 3.2.1.-),Probable beta-D-xylosidase 2 (AtBXL2) (EC 3.2.1.-),GO:0005975; GO:0004553; GO:0009505; GO:0005578,"carbohydrate metabolic process; hydrolase activity, hydrolyzing O-glycosyl compounds; plant-type cell wall; proteinaceous extracellular matrix",PF14310;PF00933;PF01915;,,,,,,,,,BXL2_ARATH,Arabidopsis thaliana (Mouse-ear cress),arabinan catabolic process [GO:0031222]; xylan catabolic process [GO:0045493] comp75256_c0_seq1,203,46.798,0.54304778,3,10,,,,,,,,,4.00E-13,CHOYP_NEMVEDRAFT_V1G239043.2.6,,,,,,,,, comp75256_c1_seq1,329,48.6322,0.67126266,8,0,,4.00E-19,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp75281_c0_seq1,204,51.9608,0.46154955,4,5,,4.00E-19,Q9GV77,Extracellular matrix protein 3 (FREM2 homolog),Extracellular matrix protein 3 (FREM2 homolog),GO:0005509; GO:0007154; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; cell communication; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF03160;,1.00E-12,CHOYP_FREM2.1.1,,,,,,,FREM2_LYTVA,Lytechinus variegatus (Green sea urchin) (Variegated urchin),cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp75288_c1_seq1,334,42.515,0.40264784,17,15,,2.00E-38,Q7ZYC4,Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2),Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2),GO:0005524; GO:0005737; GO:0001676; GO:0004467,ATP binding; cytoplasm; long-chain fatty acid metabolic process; long-chain fatty acid-CoA ligase activity,PF00501;,3.00E-11,CHOYP_LOC100372454.1.1,,,,,,,ACBG2_XENLA,Xenopus laevis (African clawed frog), comp75293_c0_seq1,655,47.1756,0.66542843,20,31,,3.00E-19,O89026,Roundabout homolog 1,Roundabout homolog 1,GO:0030673; GO:0016199; GO:0016021; GO:0060763; GO:0008285; GO:0021891,axolemma; axon midline choice point recognition; integral to membrane; mammary duct terminal end bud growth; negative regulation of cell proliferation; olfactory bulb interneuron development,PF00041;PF07679;,,,,,,,,,ROBO1_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Rho protein signal transduction [GO:0035025]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281] comp75294_c0_seq1,279,45.1613,0.70994827,4,0,,5.00E-17,Q3UPC7,Uncharacterized protein KIAA0825 homolog,Uncharacterized protein KIAA0825 homolog,,,PF14906;,2.00E-13,CHOYP_LOC100889442.1.1,,,,,,,K0825_MOUSE,Mus musculus (Mouse), comp75295_c0_seq1,250,43.6,0.1783966,5,23,,3.00E-41,Q5ZKQ6,DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B),DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B),GO:0003677; GO:0006281; GO:0006261; GO:0003887; GO:0008622,DNA binding; DNA repair; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; epsilon DNA polymerase complex,PF04042;PF12213;,5.00E-51,CHOYP_DPOE2.1.1,,,,,,,DPOE2_CHICK,Gallus gallus (Chicken),DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] comp75308_c0_seq1,442,38.914,0.23962259,10,31,,8.00E-12,Q9BU70,Nef-associated protein 1 (EC 3.1.2.-) (Thioesterase NAP1),tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O),GO:0016787; GO:0019048,hydrolase activity; modulation by virus of host morphology or physiology,PF01980;,,,,,,,,,NAP1_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp75318_c0_seq1,734,44.6866,0.63457325,4,0,,3.00E-43,Q9UL59,Zinc finger protein 214 (BWSCR2-associated zinc finger protein 1) (BAZ-1),Zinc finger protein 214 (BWSCR2-associated zinc finger protein 1) (BAZ-1),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZN214_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp75318_c0_seq2,564,45.3901,0.5211232,0,0,,7.00E-61,Q8VDL9,Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5),Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5),GO:0001077; GO:0030154; GO:0005737; GO:0046872; GO:0043433; GO:0045879; GO:0000122; GO:0007399; GO:0016607; GO:0005667; GO:0044212,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; cell differentiation; cytoplasm; metal ion binding; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; nervous system development; nuclear speck; transcription factor complex; transcription regulatory region DNA binding,PF13912;,1.00E-56,CHOYP_LOC101159893.1.1,,,,,,,GLIS2_MOUSE,Mus musculus (Mouse),"cell differentiation involved in kidney development [GO:0061005]; kidney development [GO:0001822]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of transcription from RNA polymerase II promoter involved in kidney development [GO:0060994]" comp75335_c0_seq1,588,39.2857,0.61869927,17,48,,1.00E-11,Q5RAE6,Zinc finger protein 24,Zinc finger protein 24,GO:0046872; GO:0042552; GO:0045892; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"metal ion binding; myelination; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZNF24_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"myelination [GO:0042552]; transcription, DNA-templated [GO:0006351]" comp75338_c0_seq1,386,61.399,1.14713031,0,50,,3.00E-12,P09122,DNA polymerase III subunit gamma/tau (EC 2.7.7.7),DNA polymerase III subunit gamma/tau (EC 2.7.7.7),GO:0005524; GO:0003677; GO:0009360; GO:0006260; GO:0003887; GO:0017111,ATP binding; DNA binding; DNA polymerase III complex; DNA replication; DNA-directed DNA polymerase activity; nucleoside-triphosphatase activity,PF12169;,,,,,,,,,DPO3X_BACSU,Bacillus subtilis (strain 168),DNA-dependent DNA replication [GO:0006261] comp75361_c0_seq1,514,37.9377,0.96357398,17,46,,6.00E-28,P70345,Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W) (c98),Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W) (c98),GO:0060011; GO:0005829; GO:0097192; GO:0031966; GO:0043066,Sertoli cell proliferation; cytosol; extrinsic apoptotic signaling pathway in absence of ligand; mitochondrial membrane; negative regulation of apoptotic process,PF00452;PF02180;,,,,,,,,,B2CL2_MOUSE,Mus musculus (Mouse),extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; Sertoli cell proliferation [GO:0060011] comp75362_c0_seq1,496,39.9194,0.92217672,4,0,,7.00E-06,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp75362_c0_seq2,552,39.4928,1.13320044,0,8,,5.00E-06,Q9NYQ6,Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2),GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007417; GO:0048105; GO:0001736; GO:0042249; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity; establishment of planar polarity of embryonic epithelium; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_HUMAN,Homo sapiens (Human),"anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" comp75377_c1_seq1,501,46.9062,0.76859449,16,19,,3.00E-56,P00518,"Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)","Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)",GO:0005524; GO:0005978; GO:0004689; GO:0005964; GO:0050321,ATP binding; glycogen biosynthetic process; phosphorylase kinase activity; phosphorylase kinase complex; tau-protein kinase activity,PF00069;,2.00E-77,CHOYP_PHUM_PHUM607620.1.1,,,,,,,PHKG1_RABIT,Oryctolagus cuniculus (Rabbit),glycogen biosynthetic process [GO:0005978] comp75379_c0_seq2,262,35.4962,0.74929867,4,0,,3.00E-29,Q800H9,Heparan-sulfate 6-O-sulfotransferase 2 (HS 6-OST-2) (HS6ST-2) (EC 2.8.2.-),Heparan-sulfate 6-O-sulfotransferase 2 (HS 6-OST-2) (HS6ST-2) (EC 2.8.2.-),GO:0030154; GO:0048048; GO:0017095; GO:0016021; GO:0007517; GO:0001569,cell differentiation; embryonic eye morphogenesis; heparan sulfate 6-O-sulfotransferase activity; integral to membrane; muscle organ development; patterning of blood vessels,PF03567;,,,,,,,,,H6ST2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; muscle organ development [GO:0007517]; patterning of blood vessels [GO:0001569]" comp75386_c0_seq1,259,43.6293,0.43190013,6,2,,2.00E-23,Q7RTS9,Dymeclin (Dyggve-Melchior-Clausen syndrome protein),Dymeclin (Dyggve-Melchior-Clausen syndrome protein),GO:0005794; GO:0007030; GO:0060348; GO:0005634; GO:0005886,Golgi apparatus; Golgi organization; bone development; nucleus; plasma membrane,,7.00E-24,CHOYP_LOC100374358.1.1,,,,,,,DYM_HUMAN,Homo sapiens (Human),bone development [GO:0060348]; Golgi organization [GO:0007030] comp75397_c0_seq1,336,45.5357,0.63346426,8,6,,5.00E-10,Q9GMT4,MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment),GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF00629;,,,,,,,,,MDGA2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp75427_c0_seq1,721,42.7184,0.24371355,31,38,,4.00E-27,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp75444_c0_seq1,330,39.3939,0.62913384,0,31,,5.00E-19,Q5YKK9,Melanopsin (Opsin-4),Melanopsin (Opsin-4),GO:0005502; GO:0008020; GO:0016021; GO:0007602; GO:0005886; GO:0018298; GO:0042752; GO:0016056; GO:0048511; GO:0007601,11-cis retinal binding; G-protein coupled photoreceptor activity; integral to membrane; phototransduction; plasma membrane; protein-chromophore linkage; regulation of circadian rhythm; rhodopsin mediated signaling pathway; rhythmic process; visual perception,PF00001;,,,,,,,,,OPN4_FELCA,Felis catus (Cat) (Felis silvestris catus),cellular response to light stimulus [GO:0071482]; G-protein coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; rhodopsin mediated signaling pathway [GO:0016056]; rhythmic process [GO:0048511]; visual perception [GO:0007601] comp75464_c0_seq1,228,62.7193,0.94444079,0,6,,9.00E-14,P0AGI0,Phosphate transport system permease protein PstC,Phosphate transport system permease protein PstC,GO:0005315; GO:0016021; GO:0006817; GO:0005886,inorganic phosphate transmembrane transporter activity; integral to membrane; phosphate ion transport; plasma membrane,PF00528;,,,,,,,,,PSTC_SHIFL,Shigella flexneri,phosphate ion transport [GO:0006817] comp75473_c0_seq1,632,37.5,0.80354144,20,8,,,,,,,,,1.00E-12,CHOYP_DPSE_GA18988.1.1,,,,,,,,, comp75543_c0_seq2,358,45.8101,0.69449947,4,0,,9.00E-29,Q7Z7M0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872; GO:0005198,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity; structural molecule activity,PF00431;PF12947;PF07645;PF00053;PF01437;,9.00E-18,CHOYP_LOC100749345.1.1,,,,,,,MEGF8_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp75587_c0_seq1,281,44.1281,0.8122648,2,17,,4.00E-08,Q8AXY6,"Muscle, skeletal receptor tyrosine protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)","Muscle, skeletal receptor tyrosine protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)",GO:0005524; GO:0030154; GO:0030054; GO:0016021; GO:0007275; GO:0018108; GO:0005886; GO:0045211; GO:0008582; GO:0004714,ATP binding; cell differentiation; cell junction; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; plasma membrane; postsynaptic membrane; regulation of synaptic growth at neuromuscular junction; transmembrane receptor protein tyrosine kinase activity,PF01392;PF07679;PF00051;PF07714;,,,,,,,,,MUSK_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of synaptic growth at neuromuscular junction [GO:0008582] comp75588_c0_seq1,291,41.9244,1.02044216,12,35,,,,,,,,,1.00E-15,CHOYP_KLTH0E11946G.1.1,,,,,,,,, comp7559_c0_seq1,269,53.5316,0.49002492,4,3,,2.00E-45,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,4.00E-39,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp75605_c0_seq1,605,49.5868,0.43326451,20,18,,4.00E-10,Q6IN97,Putative protein FRMPD2-like (FERM and PDZ domain-containing protein 2 pseudogene 1) (PDZ domain-containing protein 5A),Putative protein FRMPD2-like (FERM and PDZ domain-containing protein 2 pseudogene 1) (FERM and PDZ domain-containing protein 2B pseudogene) (PDZ domain-containing protein 5A),,,PF00595;,,,,,,,,,FRP2L_HUMAN,Homo sapiens (Human),bicellular tight junction assembly [GO:0070830] comp75643_c0_seq1,396,39.3939,0.91898734,14,0,,2.00E-07,Q8MJV2,Neuropeptides B/W receptor type 2 (G-protein coupled receptor 8),Neuropeptides B/W receptor type 2 (G-protein coupled receptor 8),GO:0016021; GO:0008188; GO:0007218; GO:0005886,integral to membrane; neuropeptide receptor activity; neuropeptide signaling pathway; plasma membrane,PF00001;,,,,,,,,,NPBW2_BOVIN,Bos taurus (Bovine),"chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; neuropeptide signaling pathway [GO:0007218]" comp75684_c0_seq1,239,36.8201,0,53,14,,,,,,,,,4.00E-13,CHOYP_contig_052767,,,,,,,,, comp75695_c0_seq1,795,44.6541,0.27841062,25,33,,1.00E-68,Q16739,Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase),Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase),GO:0000139; GO:0008120; GO:0008544; GO:0006679; GO:0016021; GO:0044281,Golgi membrane; ceramide glucosyltransferase activity; epidermis development; glucosylceramide biosynthetic process; integral to membrane; small molecule metabolic process,PF13506;,2.00E-56,CHOYP_SMP_160210.1.1,,,,,,,CEGT_HUMAN,Homo sapiens (Human),epidermis development [GO:0008544]; glucosylceramide biosynthetic process [GO:0006679]; glycosphingolipid biosynthetic process [GO:0006688]; glycosphingolipid metabolic process [GO:0006687]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp75698_c1_seq1,1000,43.6,0.50825133,45,11,,1.00E-76,Q5HYM0,Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B),Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B),GO:0004519; GO:0046872; GO:0090305,endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,PF11977;,7.00E-69,CHOYP_LOC101065570.1.1,,,,,,,ZC12B_HUMAN,Homo sapiens (Human), comp75707_c0_seq1,229,41.048,0.41667461,0,19,,1.00E-10,B3A0P4,Uncharacterized shell protein 26 (BMSP-like protein) (Fragment),Uncharacterized shell protein 26 (BMSP-like protein) (Fragment),GO:0005576,extracellular region,,,,,,,,,,USP26_LOTGI,Lottia gigantea (Giant owl limpet), comp75743_c0_seq1,252,67.4603,1.29727653,0,13,,6.00E-11,Q44879,Carboxy-terminal-processing protease (C-terminal-processing protease) (EC 3.4.21.102),Carboxy-terminal-processing protease (C-terminal-processing protease) (EC 3.4.21.102),GO:0005576; GO:0006508; GO:0008236,extracellular region; proteolysis; serine-type peptidase activity,PF13180;PF03572;,,,,,,,,,CTPA_BARBK,Bartonella bacilliformis (strain ATCC 35685 / KC583), comp75750_c0_seq1,423,45.3901,0.57459384,11,8,,6.00E-21,Q32NU8,Tetratricopeptide repeat protein 25 (TPR repeat protein 25),Tetratricopeptide repeat protein 25 (TPR repeat protein 25),,,PF13181;,6.00E-15,CHOYP_LOC100372889.2.2,,,,,,,TTC25_XENLA,Xenopus laevis (African clawed frog), comp75757_c0_seq2,334,42.2156,0.81377248,7,12,,1.00E-08,Q9C0R2,,,,,,,,,,,,,,RTF22_SCHPO,, comp75765_c0_seq2,793,49.5586,0.69927066,8,0,,1.00E-34,B2GV17,Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5),Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5),GO:0005829; GO:0004181; GO:0005634; GO:0035611; GO:0006508; GO:0015631; GO:0008270,cytosol; metallocarboxypeptidase activity; nucleus; protein branching point deglutamylation; proteolysis; tubulin binding; zinc ion binding,PF00246;,5.00E-51,CHOYP_CBPC5.1.1,,,,,,,CBPC5_RAT,Rattus norvegicus (Rat),defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608] comp75766_c0_seq1,510,45.4902,1.10162481,9,29,,1.00E-08,Q63155,Netrin receptor DCC (Tumor suppressor protein DCC),Netrin receptor DCC (Tumor suppressor protein DCC),GO:0033564; GO:0006915; GO:0030424; GO:0007411; GO:0033563; GO:0032584; GO:0016021; GO:0045121; GO:0005042; GO:0001764; GO:0070374; GO:0010976; GO:0001975; GO:0021965; GO:0003713,anterior/posterior axon guidance; apoptotic process; axon; axon guidance; dorsal/ventral axon guidance; growth cone membrane; integral to membrane; membrane raft; netrin receptor activity; neuron migration; positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron projection development; response to amphetamine; spinal cord ventral commissure morphogenesis; transcription coactivator activity,PF00041;PF07679;PF13895;PF06583;,,,,,,,,,DCC_RAT,Rattus norvegicus (Rat),apoptotic process [GO:0006915]; axon guidance [GO:0007411]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron projection development [GO:0010976]; response to amphetamine [GO:0001975] comp75774_c0_seq1,208,38.9423,0.63720985,2,6,,4.00E-07,Q62645,"Glutamate receptor ionotropic, NMDA 2D (GluN2D) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)","Glutamate receptor ionotropic, NMDA 2D (GluN2D) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)",GO:0004972; GO:0017146; GO:0030054; GO:0005234; GO:0016595; GO:0042165; GO:0045211; GO:0035249; GO:0022843,"N-methyl-D-aspartate selective glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor complex; cell junction; extracellular-glutamate-gated ion channel activity; glutamate binding; neurotransmitter binding; postsynaptic membrane; synaptic transmission, glutamatergic; voltage-gated cation channel activity",PF01094;PF00060;PF10613;,,,,,,,,,NMDE4_RAT,Rattus norvegicus (Rat),"synaptic transmission, glutamatergic [GO:0035249]" comp75783_c1_seq1,651,46.0829,1.08451973,10,77,,3.00E-63,Q5R7L7,Ras-related protein Rab-5C,Ras-related protein Rab-5C,GO:0019003; GO:0005525; GO:0031901; GO:0005811; GO:0005886; GO:0015031; GO:0007264,GDP binding; GTP binding; early endosome membrane; lipid particle; plasma membrane; protein transport; small GTPase mediated signal transduction,PF00071;,1.00E-32,CHOYP_LOC578627.1.1,,,,,,,RAB5C_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),plasma membrane to endosome transport [GO:0048227]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp75793_c0_seq1,460,38.913,0.40652749,14,31,,2.00E-16,Q8N9F8,Zinc finger protein 454,Zinc finger protein 454,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN454_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp75794_c0_seq1,483,51.9669,0.99168052,0,57,,1.00E-19,Q6GNV7,Disrupted in renal carcinoma protein 2 homolog,Disrupted in renal carcinoma protein 2 homolog,GO:0016021; GO:0005765; GO:0055085,integral to membrane; lysosomal membrane; transmembrane transport,PF07690;,,,,,,,,,DIRC2_XENLA,Xenopus laevis (African clawed frog),transmembrane transport [GO:0055085] comp75808_c0_seq1,222,37.8378,0.25515392,3,5,,2.00E-20,Q8CHJ1,Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) (Liver regeneration-related protein LRRGT00059),Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) (Liver regeneration-related protein LRRGT00059),GO:0006506; GO:0042765,GPI anchor biosynthetic process; GPI-anchor transamidase complex,PF06728;,,,,,,,,,PIGU_RAT,Rattus norvegicus (Rat),GPI anchor biosynthetic process [GO:0006506] comp75812_c0_seq1,897,43.3668,0.35834043,34,16,,9.00E-138,Q24K02,Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin),Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin),GO:0005524; GO:0050435; GO:0010815; GO:0009986; GO:0005829; GO:0008340; GO:0005615; GO:0043559; GO:1901143; GO:0004222; GO:0005739; GO:0005634; GO:0005777; GO:0005886; GO:0032461; GO:0051260; GO:0051603; GO:0010992; GO:0008270,ATP binding; beta-amyloid metabolic process; bradykinin catabolic process; cell surface; cytosol; determination of adult lifespan; extracellular space; insulin binding; insulin catabolic process; metalloendopeptidase activity; mitochondrion; nucleus; peroxisome; plasma membrane; positive regulation of protein oligomerization; protein homooligomerization; proteolysis involved in cellular protein catabolic process; ubiquitin homeostasis; zinc ion binding,PF00675;PF05193;PF16187;,5.00E-58,CHOYP_IDE.1.3,,,,,,,IDE_BOVIN,Bos taurus (Bovine),beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; insulin catabolic process [GO:1901143]; peptide catabolic process [GO:0043171]; positive regulation of protein oligomerization [GO:0032461]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992] comp75827_c0_seq1,222,63.0631,0.8792459,0,13,,6.00E-20,B9MJ16,Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase),Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase),GO:0005525; GO:0044206; GO:0000287; GO:0004845; GO:0006223,GTP binding; UMP salvage; magnesium ion binding; uracil phosphoribosyltransferase activity; uracil salvage,PF14681;,,,,,,,,,UPP_ACIET,Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)),UMP salvage [GO:0044206]; uracil salvage [GO:0006223] comp75854_c0_seq1,246,62.6016,1.2081495,0,6,,6.00E-50,Q6A9W5,Probable cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase) (LAP) (EC 3.4.11.10) (Leucyl aminopeptidase),Probable cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase) (LAP) (EC 3.4.11.10) (Leucyl aminopeptidase),GO:0004177; GO:0005737; GO:0030145; GO:0008235; GO:0006508,aminopeptidase activity; cytoplasm; manganese ion binding; metalloexopeptidase activity; proteolysis,PF00883;PF02789;,,,,,,,,,AMPA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp75897_c0_seq1,260,45.3846,0.77197238,4,8,,2.00E-36,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,4.00E-52,CHOYP_DNAH5.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp7589_c0_seq1,257,43.1907,0.42157501,2,8,,1.00E-15,Q8N7A1,Kelch domain-containing protein 1,Kelch domain-containing protein 1,GO:0005737,cytoplasm,,,,,,,,,,KLDC1_HUMAN,Homo sapiens (Human), comp75920_c0_seq1,381,41.9948,0.96465311,20,8,,1.00E-06,Q8C206,Probable G-protein coupled receptor 157,Probable G-protein coupled receptor 157,GO:0004930; GO:0016021; GO:0005886,G-protein coupled receptor activity; integral to membrane; plasma membrane,PF00002;,,,,,,,,,GP157_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166] comp75940_c0_seq1,313,37.6997,0.47048727,6,20,,4.00E-12,Q62255,Sal-like protein 3 (MSal) (Spalt-like protein 3),Sal-like protein 3 (MSal) (Spalt-like protein 3),GO:0003677; GO:0035136; GO:0035137; GO:0046872; GO:0045879; GO:0005634; GO:0021891; GO:0006355; GO:0006351,"DNA binding; forelimb morphogenesis; hindlimb morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; nucleus; olfactory bulb interneuron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,SALL3_MOUSE,Mus musculus (Mouse),"forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp75966_c0_seq1,525,37.5238,1.03073806,8,25,,8.00E-17,Q64458,Cytochrome P450 2C29 (EC 1.14.14.1) (Aldehyde oxygenase) (CYPIIC29) (Cytochrome P-450 MUT-2),Cytochrome P450 2C29 (EC 1.14.14.1) (Aldehyde oxygenase) (CYPIIC29) (Cytochrome P-450 MUT-2),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2CT_MOUSE,Mus musculus (Mouse),epoxygenase P450 pathway [GO:0019373] comp75987_c0_seq1,242,47.5207,0.80903318,5,8,,6.00E-29,O57382,Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid),Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid),GO:0005509; GO:0030154; GO:0005576; GO:0004222; GO:0007275; GO:0006508; GO:0008270,calcium ion binding; cell differentiation; extracellular region; metalloendopeptidase activity; multicellular organismal development; proteolysis; zinc ion binding,PF01400;PF00431;PF00008;,2.00E-55,CHOYP_LOC100643173.2.2,,,,,,,TLL2_XENLA,Xenopus laevis (African clawed frog),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp75998_c0_seq1,247,49.7976,1.00271185,2,0,,3.00E-14,P04629,High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA),High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA),GO:0005524; GO:0030183; GO:0007265; GO:0060009; GO:0000186; GO:0007190; GO:0007202; GO:0007568; GO:0030424; GO:0007411; GO:0060385; GO:0009986; GO:0071316; GO:0031410; GO:0030425; GO:0050966; GO:0050965; GO:0010623; GO:0005769; GO:0031901; GO:0005887; GO:0005770; GO:0031902; GO:0007611; GO:0042490; GO:0008285; GO:0043524; GO:0048406; GO:0010465; GO:0043025; GO:0048011; GO:0021553; GO:0048015; GO:0070374; GO:0051092; GO:0032320; GO:0046579; GO:0045766; GO:0010976; GO:0043068; GO:0051968; GO:0046777; GO:0043234; GO:0042803; GO:0014823; GO:0048678; GO:0042493; GO:0051602; GO:0045471; GO:0051599; GO:0031667; GO:0009314; GO:0048485; GO:0004714,"ATP binding; B cell differentiation; Ras protein signal transduction; Sertoli cell development; activation of MAPKK activity; activation of adenylate cyclase activity; activation of phospholipase C activity; aging; axon; axon guidance; axonogenesis involved in innervation; cell surface; cellular response to nicotine; cytoplasmic vesicle; dendrite; detection of mechanical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception of pain; developmental programmed cell death; early endosome; early endosome membrane; integral to plasma membrane; late endosome; late endosome membrane; learning or memory; mechanoreceptor differentiation; negative regulation of cell proliferation; negative regulation of neuron apoptotic process; nerve growth factor binding; nerve growth factor receptor activity; neuronal cell body; neurotrophin TRK receptor signaling pathway; olfactory nerve development; phosphatidylinositol-mediated signaling; positive regulation of ERK1 and ERK2 cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of Ras GTPase activity; positive regulation of Ras protein signal transduction; positive regulation of angiogenesis; positive regulation of neuron projection development; positive regulation of programmed cell death; positive regulation of synaptic transmission, glutamatergic; protein autophosphorylation; protein complex; protein homodimerization activity; response to activity; response to axon injury; response to drug; response to electrical stimulus; response to ethanol; response to hydrostatic pressure; response to nutrient levels; response to radiation; sympathetic nervous system development; transmembrane receptor protein tyrosine kinase activity",PF13855;PF07714;PF16920;,,,,,,,,,NTRK1_HUMAN,Homo sapiens (Human),"activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; microtubule-based movement [GO:0007018]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to activity [GO:0014823]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]" comp75998_c0_seq2,247,40.8907,1.07066119,2,0,,1.00E-18,Q62371,"Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)","Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)",GO:0005524; GO:0031214; GO:0007155; GO:0035988; GO:0005518; GO:0030199; GO:0003416; GO:0016021; GO:0001503; GO:0005886; GO:0090091; GO:0010763; GO:0048146; GO:0045669; GO:0045860; GO:0051091; GO:0046777; GO:0038062; GO:0030500,ATP binding; biomineral tissue development; cell adhesion; chondrocyte proliferation; collagen binding; collagen fibril organization; endochondral bone growth; integral to membrane; ossification; plasma membrane; positive regulation of extracellular matrix disassembly; positive regulation of fibroblast migration; positive regulation of fibroblast proliferation; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; positive regulation of sequence-specific DNA binding transcription factor activity; protein autophosphorylation; protein tyrosine kinase collagen receptor activity; regulation of bone mineralization,PF00754;PF07714;,3.00E-22,CHOYP_LOC100903889.1.1,,,,,,,DDR2_MOUSE,Mus musculus (Mouse),biomineral tissue development [GO:0031214]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell proliferation [GO:0008284]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp76004_c0_seq1,204,45.098,1.16480072,0,6,,8.00E-12,P84076,Neuron-specific calcium-binding protein hippocalcin (P23K),Neuron-specific calcium-binding protein hippocalcin (P23K),GO:0003779; GO:0005509,actin binding; calcium ion binding,PF00036;PF13499;,,,,,,,,,HPCA_RAT,Rattus norvegicus (Rat),activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to electrical stimulus [GO:0071257]; cellular response to monosodium glutamate [GO:1904009]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein targeting to membrane [GO:0090314]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; response to L-glutamate [GO:1902065]; response to organic cyclic compound [GO:0014070]; retina development in camera-type eye [GO:0060041] comp76019_c0_seq1,679,43.7408,0.99080444,11,51,,5.00E-39,Q17QK8,Sepiapterin reductase (SPR) (EC 1.1.1.153),Sepiapterin reductase (SPR) (EC 1.1.1.153),GO:0005737; GO:0006809; GO:0005634; GO:0004757; GO:0006729,cytoplasm; nitric oxide biosynthetic process; nucleus; sepiapterin reductase activity; tetrahydrobiopterin biosynthetic process,PF00106;,,,,,,,,,SPRE_BOVIN,Bos taurus (Bovine),tetrahydrobiopterin biosynthetic process [GO:0006729] comp76031_c0_seq1,355,62.2535,1.02664089,0,21,,1.00E-70,Q6A6H1,NADH-quinone oxidoreductase subunit N (EC 1.6.99.5) (NADH dehydrogenase I subunit N) (NDH-1 subunit N),NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N),GO:0042773; GO:0008137; GO:0016021; GO:0005886; GO:0048038; GO:0006810,ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; integral to membrane; plasma membrane; quinone binding; transport,PF00361;,,,,,,,,,NUON_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),ATP synthesis coupled electron transport [GO:0042773]; transport [GO:0006810] comp76058_c0_seq1,347,55.0432,0.78115127,6,5,,7.00E-22,Q99N01,Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12),GO:0016021; GO:0005886; GO:0042403; GO:0015349,integral to membrane; plasma membrane; thyroid hormone metabolic process; thyroid hormone transmembrane transporter activity,PF07648;PF03137;,,,,,,,,,SO4A1_RAT,Rattus norvegicus (Rat),sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] comp76082_c0_seq1,357,40.6162,1.17400613,8,18,,7.00E-06,Q8CGM1,Brain-specific angiogenesis inhibitor 2,Adhesion G protein-coupled receptor B2 (Brain-specific angiogenesis inhibitor 2),GO:0004930; GO:0016021; GO:0016525; GO:0007218; GO:0007422; GO:0005886,G-protein coupled receptor activity; integral to membrane; negative regulation of angiogenesis; neuropeptide signaling pathway; peripheral nervous system development; plasma membrane,PF00002;PF16489;PF01825;PF00090;,,,,,,,,,BAI2_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166]; negative regulation of angiogenesis [GO:0016525]; peripheral nervous system development [GO:0007422]; positive regulation of synapse assembly [GO:0051965] comp76084_c0_seq1,553,45.9313,0.3806859,24,7,,5.00E-52,Q1LZA0,GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B),GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B),GO:0006506; GO:0005789; GO:0016021; GO:0016757,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring glycosyl groups",PF03901;,3.00E-45,CHOYP_PIGB.1.1,,,,,,,PIGB_BOVIN,Bos taurus (Bovine),GPI anchor biosynthetic process [GO:0006506] comp76087_c1_seq1,392,51.0204,0.99052968,24,4,,,,,,,,,3.00E-11,CHOYP_LOC100489553.10.14,,,,,,,,, comp76116_c0_seq1,226,69.0265,1.15837659,0,8,,1.00E-11,P76113,NADPH-dependent curcumin reductase (EC 1.3.1.n3) (NADPH-dependent curcumin/dihydrocurcumin reductase),NADPH-dependent curcumin reductase (EC 1.3.1.n3) (NADPH-dependent curcumin/dihydrocurcumin reductase),GO:0016628; GO:0008270,"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; zinc ion binding",PF00107;,,,,,,,,,CURA_ECOLI,Escherichia coli (strain K12), comp76117_c0_seq1,279,39.7849,0.54652621,5,0,,1.00E-15,Q811B1,Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I),Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I),GO:0000139; GO:0008375; GO:0034605; GO:0030206; GO:0005789; GO:0015012; GO:0016021; GO:0030158,Golgi membrane; acetylglucosaminyltransferase activity; cellular response to heat; chondroitin sulfate biosynthetic process; endoplasmic reticulum membrane; heparan sulfate proteoglycan biosynthetic process; integral to membrane; protein xylosyltransferase activity,PF02485;PF12529;,,,,,,,,,XYLT1_MOUSE,Mus musculus (Mouse),cellular response to heat [GO:0034605]; chondroitin sulfate biosynthetic process [GO:0030206]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] comp76148_c0_seq1,271,50.5535,0.40684315,3,10,,1.00E-10,Q8NE09,Regulator of G-protein signaling 22 (RGS22),Regulator of G-protein signaling 22 (RGS22),GO:0005096; GO:0005737; GO:0005886; GO:0038032,GTPase activator activity; cytoplasm; plasma membrane; termination of G-protein coupled receptor signaling pathway,PF00615;,,,,,,,,,RGS22_HUMAN,Homo sapiens (Human),negative regulation of signal transduction [GO:0009968] comp76153_c1_seq1,339,45.1327,0.93151496,0,52,,6.00E-10,Q9CZJ2,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_MOUSE,Mus musculus (Mouse), comp76161_c0_seq1,238,43.6975,0.18356699,2,16,,2.00E-23,Q8AYC9,Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1),Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1),GO:0005524; GO:0006975; GO:0031572; GO:0005813; GO:0000785; GO:0048096; GO:0000794; GO:0005737; GO:0000724; GO:0035402; GO:0045839; GO:0005654; GO:0010569; GO:2000615; GO:0046602; GO:0010767,ATP binding; DNA damage induced protein phosphorylation; G2 DNA damage checkpoint; centrosome; chromatin; chromatin-mediated maintenance of transcription; condensed nuclear chromosome; cytoplasm; double-strand break repair via homologous recombination; histone kinase activity (H3-T11 specific); negative regulation of mitosis; nucleoplasm; regulation of double-strand break repair via homologous recombination; regulation of histone H3-K9 acetylation; regulation of mitotic centrosome separation; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage,PF00069;,3.00E-22,CHOYP_LOC100367549.1.1,,,,,,,CHK1_CHICK,Gallus gallus (Chicken),cellular response to DNA damage stimulus [GO:0006974]; chromatin-mediated maintenance of transcription [GO:0048096]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; G2 DNA damage checkpoint [GO:0031572]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767] comp76165_c0_seq1,213,66.6667,1.07865281,0,11,,2.00E-32,A1WAX8,3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III),3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III),GO:0004315; GO:0033818; GO:0005737; GO:0006633,3-oxoacyl-[acyl-carrier-protein] synthase activity; beta-ketoacyl-acyl-carrier-protein synthase III activity; cytoplasm; fatty acid biosynthetic process,PF08545;PF08541;,,,,,,,,,FABH_ACISJ,Acidovorax sp. (strain JS42),fatty acid biosynthetic process [GO:0006633] comp76213_c1_seq1,329,58.9666,0.87832175,1,15,,1.00E-18,P36938,Phosphoglucomutase (PGM) (EC 5.4.2.2) (Glucose phosphomutase),Phosphoglucomutase (PGM) (EC 5.4.2.2) (Glucose phosphomutase),GO:0005829; GO:0006006; GO:0000287; GO:0004614,cytosol; glucose metabolic process; magnesium ion binding; phosphoglucomutase activity,PF02878;PF02879;PF02880;PF00408;,,,,,,,,,PGM_ECOLI,Escherichia coli (strain K12),galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978] comp76217_c0_seq1,333,38.1381,0.33184601,7,39,,6.00E-10,Q3UF25,Transmembrane protein 110,Store-operated calcium entry regulator STIMATE (STIM-activating enhancer encoded by TMEM110) (STIMATE) (Transmembrane protein 110),GO:0016021,integral to membrane,PF12400;,1.00E-29,CHOYP_LOC100371786.1.1,,,,,,,TM110_MOUSE,Mus musculus (Mouse),activation of store-operated calcium channel activity [GO:0032237]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; positive regulation of NFAT protein import into nucleus [GO:0051533] comp76226_c0_seq1,596,48.9933,0.79256778,36,0,,4.00E-72,Q8UVC3,Inversin,Inversin,GO:0016055; GO:0005737; GO:0005856; GO:0007275,Wnt receptor signaling pathway; cytoplasm; cytoskeleton; multicellular organismal development,PF12796;PF00612;,2.00E-78,CHOYP_INVS.5.6,,,,,,,INVS_CHICK,Gallus gallus (Chicken),multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055] comp76243_c0_seq1,751,38.8815,0.39278322,30,53,,6.00E-97,Q6DEL2,Cleft lip and palate transmembrane protein 1 homolog,Cleft lip and palate transmembrane protein 1 homolog,GO:0030154; GO:0016021; GO:0007275,cell differentiation; integral to membrane; multicellular organismal development,PF05602;,4.00E-71,CHOYP_CLPT1.1.1,,,,,,,CLPT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp76250_c0_seq1,221,44.7964,0.54815937,5,27,,1.00E-18,Q8N0X4,"Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (EC 4.1.-.-)","Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (Beta-methylmalate synthase) (EC 2.3.3.-) (Malate synthase) (EC 2.3.3.9)",GO:0006725; GO:0008815; GO:0009346; GO:0046872; GO:0005739,cellular aromatic compound metabolic process; citrate (pro-3S)-lyase activity; citrate lyase complex; metal ion binding; mitochondrion,PF03328;,,,,,,,,,CLYBL_HUMAN,Homo sapiens (Human), comp76257_c0_seq1,293,41.6382,0.39505969,5,4,,1.00E-48,A4IID4,Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67),Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67),GO:0004430; GO:0005524; GO:0005741; GO:0006661; GO:0048015; GO:0030867,1-phosphatidylinositol 4-kinase activity; ATP binding; mitochondrial outer membrane; phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling; rough endoplasmic reticulum membrane,PF00454;,2.00E-63,CHOYP_PI4KB.1.1,,,,,,,PI4KB_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),phosphatidylinositol-mediated signaling [GO:0048015] comp76257_c2_seq1,303,43.2343,0.43080299,3,9,,4.00E-39,O08561,Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67),Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67),GO:0004430; GO:0005524; GO:0005794; GO:0005829; GO:0005741; GO:0006661; GO:0048015; GO:0005886; GO:0030867; GO:0007165,1-phosphatidylinositol 4-kinase activity; ATP binding; Golgi apparatus; cytosol; mitochondrial outer membrane; phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling; plasma membrane; rough endoplasmic reticulum membrane; signal transduction,PF00454;,,,,,,,,,PI4KB_RAT,Rattus norvegicus (Rat),phosphatidylinositol-mediated signaling [GO:0048015]; signal transduction [GO:0007165] comp76351_c0_seq1,305,44.2623,1.23887971,5,24,,1.00E-11,Q9U489,Protein lin-41 (Abnormal cell lineage protein 41),Protein lin-41 (Abnormal cell lineage protein 41),GO:0005737; GO:0009957; GO:0007276; GO:0044268; GO:0042787; GO:0040034; GO:0045604; GO:0045138; GO:0004842; GO:0008270,"cytoplasm; epidermal cell fate specification; gamete generation; multicellular organismal protein metabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of development, heterochronic; regulation of epidermal cell differentiation; tail tip morphogenesis; ubiquitin-protein ligase activity; zinc ion binding",PF00630;PF01436;,,,,,,,,,LIN41_CAEEL,Caenorhabditis elegans,"epidermal cell fate specification [GO:0009957]; gamete generation [GO:0007276]; multicellular organismal protein metabolic process [GO:0044268]; nematode male tail tip morphogenesis [GO:0045138]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of development, heterochronic [GO:0040034]; regulation of epidermal cell differentiation [GO:0045604]" comp76378_c0_seq1,202,39.604,0.7631766,6,0,,3.00E-12,Q8R307,Vacuolar protein sorting-associated protein 18 homolog,Vacuolar protein sorting-associated protein 18 homolog,GO:0030897; GO:0003779; GO:0005884; GO:0005769; GO:0007032; GO:0006886; GO:0031902; GO:0005765; GO:0007040; GO:0046872; GO:0016192,HOPS complex; actin binding; actin filament; early endosome; endosome organization; intracellular protein transport; late endosome membrane; lysosomal membrane; lysosome organization; metal ion binding; vesicle-mediated transport,PF00637;PF05131;,2.00E-17,CHOYP_VPS18.1.1,,,,,,,VPS18_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904]; viral entry into host cell [GO:0046718] comp76382_c0_seq1,494,47.3684,0.47132691,25,8,,1.00E-22,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp76418_c0_seq1,314,55.414,1.34311822,4,11,,8.00E-57,Q6A9H6,Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase),Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase),GO:0055129; GO:0050661; GO:0005737; GO:0004350,L-proline biosynthetic process; NADP binding; cytoplasm; glutamate-5-semialdehyde dehydrogenase activity,PF00171;,,,,,,,,,PROA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),L-proline biosynthetic process [GO:0055129] comp76443_c0_seq1,499,32.2645,0.61728643,12,18,,3.00E-10,Q96NI8,Zinc finger protein 570,Zinc finger protein 570,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN570_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp76470_c0_seq1,755,43.8411,0.66248108,16,32,,1.00E-36,Q96JQ0,Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1),Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1),GO:0005509; GO:0016339; GO:0007156; GO:0016021; GO:0016020; GO:0005886,calcium ion binding; calcium-dependent cell-cell adhesion; homophilic cell adhesion; integral to membrane; membrane; plasma membrane,PF00028;,,,,,,,,,PCD16_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cochlea development [GO:0090102]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; post-anal tail morphogenesis [GO:0036342] comp76470_c1_seq1,313,39.6166,0.57314796,2,36,,2.00E-06,Q99JH7,Calsyntenin-3 (Alcadein-beta) (Alc-beta),Calsyntenin-3 (Alcadein-beta) (Alc-beta),GO:0000139; GO:0005509; GO:0005789; GO:0007156; GO:0016021; GO:0045211,Golgi membrane; calcium ion binding; endoplasmic reticulum membrane; homophilic cell adhesion; integral to membrane; postsynaptic membrane,PF00028;,,,,,,,,,CSTN3_MOUSE,Mus musculus (Mouse),"homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell growth [GO:0001558]; synapse assembly [GO:0007416]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249]" comp76494_c1_seq1,540,36.6667,0.39675359,12,35,,2.00E-20,Q9HC78,Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288),Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288),GO:0003677; GO:0001078; GO:0046872; GO:0005634,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; metal ion binding; nucleus,PF00651;PF00096;,,,,,,,,,ZBT20_HUMAN,Homo sapiens (Human),"positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; transcription, DNA-templated [GO:0006351]" comp76521_c0_seq1,472,42.3729,0.85447995,9,28,,1.00E-65,Q63340,Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase MKP-X) (Fragment),Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase MKP-X) (Fragment),GO:0017017; GO:0005829; GO:0004725,MAP kinase tyrosine/serine/threonine phosphatase activity; cytosol; protein tyrosine phosphatase activity,PF00782;,8.00E-58,CHOYP_BRAFLDRAFT_60200.2.3,,,,,,,DUS7_RAT,Rattus norvegicus (Rat), comp76528_c0_seq1,248,50.8065,0.62991158,1,13,,1.00E-19,P10079,Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),GO:0032579; GO:0005509; GO:0016023; GO:0005615,apical lamina of hyaline layer; calcium ion binding; cytoplasmic membrane-bounded vesicle; extracellular space,PF01382;PF00431;PF00008;,,,,,,,,,FBP1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp76528_c1_seq1,289,44.9827,0.87680566,0,27,,1.00E-10,Q7Z3S9,Notch homolog 2 N-terminal-like protein,Notch homolog 2 N-terminal-like protein,GO:0007219; GO:0005509; GO:0030154; GO:0005737; GO:0005576; GO:0007275,Notch signaling pathway; calcium ion binding; cell differentiation; cytoplasm; extracellular region; multicellular organismal development,PF00008;PF07645;,,,,,,,,,NT2NL_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; Notch signaling pathway [GO:0007219] comp76552_c1_seq1,653,34.7626,1.16767857,22,48,,4.00E-06,P83425,Heavy metal-binding protein HIP,Heavy metal-binding protein HIP,GO:0005576; GO:0046872,extracellular region; metal ion binding,PF00386;,,,,,,,,,HIP_MYTED,Mytilus edulis (Blue mussel), comp76565_c0_seq1,369,61.2466,1.13444229,3,15,,1.00E-32,Q3SRI8,Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS),Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS),GO:0005524; GO:0005737; GO:0004819; GO:0006425; GO:0006424,ATP binding; cytoplasm; glutamine-tRNA ligase activity; glutaminyl-tRNA aminoacylation; glutamyl-tRNA aminoacylation,PF00749;PF03950;,,,,,,,,,SYQ_NITWN,Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255),glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424] comp76588_c0_seq1,211,50.7109,1.20886536,2,7,,,,,,,,,,,2.00E-26,ruditapes_c25162,,,,,,, comp76596_c0_seq1,604,37.4172,0.64256712,6,19,,3.00E-06,Q8BGF9,Solute carrier family 25 member 44,Solute carrier family 25 member 44,GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,,,,,,,,,S2544_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transmembrane transport [GO:0055085] comp76631_c0_seq1,245,34.6939,0.95988221,1,0,,1.00E-07,Q9ER74,Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3),GO:0016581; GO:0001105; GO:0001658; GO:0003682; GO:0042733; GO:0001158; GO:0035136; GO:0000792; GO:0035137; GO:0016575; GO:0031129; GO:0003337; GO:0046872; GO:2000384; GO:2000381; GO:0045879; GO:0000122; GO:0001843; GO:0021889; GO:0021553; GO:0045666; GO:2000177; GO:0072092; GO:0003281,NuRD complex; RNA polymerase II transcription coactivator activity; branching involved in ureteric bud morphogenesis; chromatin binding; embryonic digit morphogenesis; enhancer sequence-specific DNA binding; forelimb morphogenesis; heterochromatin; hindlimb morphogenesis; histone deacetylation; inductive cell-cell signaling; mesenchymal to epithelial transition involved in metanephros morphogenesis; metal ion binding; negative regulation of ectoderm development; negative regulation of mesoderm development; negative regulation of smoothened signaling pathway; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; olfactory bulb interneuron differentiation; olfactory nerve development; positive regulation of neuron differentiation; regulation of neural precursor cell proliferation; ureteric bud invasion; ventricular septum development,PF00096;,,,,,,,,,SALL1_MOUSE,Mus musculus (Mouse),"branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]" comp76637_c0_seq1,472,40.4661,0.41821585,9,16,,6.00E-39,A1A4R8,Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8),Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8),GO:0005680; GO:0051301; GO:0007080; GO:0070979; GO:0030071,anaphase-promoting complex; cell division; mitotic metaphase plate congression; protein K11-linked ubiquitination; regulation of mitotic metaphase/anaphase transition,PF04049;PF13414;PF13181;,,,,,,,,,CDC23_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071] comp76644_c0_seq1,201,49.7512,0.51996139,6,0,,,,,,,,,2.00E-17,CHOYP_FUCTA.2.4,,,,,,,,, comp76647_c0_seq1,382,35.6021,1.24675334,5,45,,6.00E-10,Q96CX6,Leucine-rich repeat-containing protein 58,Leucine-rich repeat-containing protein 58,,,PF13855;,,,,,,,,,LRC58_HUMAN,Homo sapiens (Human), comp76665_c0_seq1,501,40.9182,0.47873546,14,6,,1.00E-06,B3DIY3,Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like),GO:0000724; GO:0043596; GO:0031297,double-strand break repair via homologous recombination; nuclear replication fork; replication fork processing,PF14911;PF14910;,,,,,,,,,MMS22_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] comp76684_c0_seq1,255,44.7059,0.49105615,3,0,,3.00E-15,Q5G267,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_MACMU,Macaca mulatta (Rhesus macaque),exocytosis [GO:0006887] comp76694_c0_seq1,721,41.0541,0.46250375,0,6,,1.00E-21,Q9Z176,"Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta (PP2A B''-PR59) (PP2A PR59) (Protein phosphatase 2A, 59 kDa regulatory subunit B) (Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha)","Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta (PP2A B''-PR59) (PP2A PR59) (Protein phosphatase 2A, 59 kDa regulatory subunit B) (Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha)",GO:0005509; GO:0003682; GO:2000134; GO:0008285; GO:0006470; GO:0008601,calcium ion binding; chromatin binding; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell proliferation; protein dephosphorylation; protein phosphatase type 2A regulator activity,PF13499;,,,,,,,,,P2R3A_MOUSE,Mus musculus (Mouse),negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; protein dephosphorylation [GO:0006470] comp76694_c0_seq2,784,39.5408,0.42563466,7,8,,7.00E-113,Q803V3,Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma,Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma,GO:0005509; GO:0005737; GO:0005634,calcium ion binding; cytoplasm; nucleus,,3.00E-110,CHOYP_P2R3C.1.1,,,,,,,P2R3C_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; T cell homeostasis [GO:0043029] comp76701_c0_seq1,563,41.5631,0.49735607,1,79,,1.00E-07,Q2PZL6,Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0045177; GO:0001658; GO:0005509; GO:0048565; GO:0001736; GO:0003007; GO:0007156; GO:0060122; GO:0016021; GO:0001822; GO:0043931; GO:0005886; GO:0007009,apical part of cell; branching involved in ureteric bud morphogenesis; calcium ion binding; digestive tract development; establishment of planar polarity; heart morphogenesis; homophilic cell adhesion; inner ear receptor stereocilium organization; integral to membrane; kidney development; ossification involved in bone maturation; plasma membrane; plasma membrane organization,PF00028;PF00008;PF07645;PF02210;,,,,,,,,,FAT4_MOUSE,Mus musculus (Mouse),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp76728_c0_seq1,225,45.3333,0.95580512,3,8,,3.00E-20,Q8TDB6,E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),GO:0005737; GO:0006302; GO:0042393; GO:0010390; GO:0005634; GO:0004842; GO:0008270,cytoplasm; double-strand break repair; histone binding; histone monoubiquitination; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,DTX3L_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209] comp76735_c0_seq1,226,38.9381,0.58627181,0,14,,1.00E-06,O46640,Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1),Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1),GO:0047685; GO:0005737,amine sulfotransferase activity; cytoplasm,PF00685;,,,,,,,,,ST3A1_RABIT,Oryctolagus cuniculus (Rabbit), comp76750_c0_seq1,278,44.964,0.50026262,5,8,,1.00E-18,Q8N0W3,L-fucose kinase (Fucokinase) (EC 2.7.1.52),L-fucose kinase (Fucokinase) (EC 2.7.1.52),GO:0005524; GO:0005737; GO:0050201,ATP binding; cytoplasm; fucokinase activity,PF07959;PF08544;PF00288;,,,,,,,,,FUK_HUMAN,Homo sapiens (Human), comp76782_c0_seq1,210,50.9524,0.73322126,6,4,,5.00E-06,A5PJU9,Septin-1,Septin-1,GO:0005525; GO:0007049; GO:0051301; GO:0005815; GO:0030496; GO:0031105,GTP binding; cell cycle; cell division; microtubule organizing center; midbody; septin complex,PF00735;,,,,,,,,,SEPT1_BOVIN,Bos taurus (Bovine),cell division [GO:0051301]; meiotic metaphase plate congression [GO:0051311]; spindle assembly involved in female meiosis [GO:0007056] comp76783_c0_seq1,505,43.1683,0.29814932,8,32,,1.00E-06,Q3TCV3,Gamma-secretase-activating protein (GSAP) (Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form (GSAP-16K)],Gamma-secretase-activating protein (GSAP) (Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form (GSAP-16K)],GO:0005794; GO:0001540; GO:0034205; GO:0030162; GO:0005802,Golgi apparatus; beta-amyloid binding; beta-amyloid formation; regulation of proteolysis; trans-Golgi network,PF14959;,,,,,,,,,GSAP_MOUSE,Mus musculus (Mouse),positive regulation of beta-amyloid formation [GO:1902004]; regulation of proteolysis [GO:0030162] comp76841_c0_seq1,512,37.1094,1.35062328,0,42,,8.00E-16,O57337,Transcription factor HES-1 (C-HAIRY1) (Hairy and enhancer of split 1),Transcription factor HES-1 (C-HAIRY1) (Hairy and enhancer of split 1),GO:0003677; GO:0005634; GO:0006355; GO:0006351,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07527;PF00010;,,,,,,,,,HES1_CHICK,Gallus gallus (Chicken),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp76901_c0_seq1,557,42.0108,0.47563113,7,25,,1.00E-43,Q6NT16,MFS-type transporter SLC18B1 (Solute carrier family 18 member B1),MFS-type transporter SLC18B1 (Solute carrier family 18 member B1),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,2.00E-15,CHOYP_C6ORF192.1.1,,,,,,,S18B1_HUMAN,Homo sapiens (Human), comp76926_c0_seq1,209,42.5837,0.64616864,2,3,,3.00E-30,P41044,Calbindin-32,Calbindin-32,GO:0005509,calcium ion binding,PF00036;PF13499;,8.00E-22,CHOYP_CAB32.1.1,,,,,,,CAB32_DROME,Drosophila melanogaster (Fruit fly),negative regulation of response to wounding [GO:1903035]; regulation of cytosolic calcium ion concentration [GO:0051480] comp76935_c0_seq1,1232,29.5455,0.52423504,76,142,,,,,,,,,,,2.00E-23,ruditapes_c16084,,,,,,, comp76958_c0_seq1,438,47.4886,0.40894484,13,0,,3.00E-16,Q6PFX9,Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I),GO:0005794; GO:0000139; GO:0003950; GO:0016055; GO:0051301; GO:0000775; GO:0051028; GO:0007067; GO:0043392; GO:0000784; GO:0005643; GO:0018105; GO:0018107; GO:0090263; GO:0032212; GO:0045944; GO:0070213; GO:0070198; GO:0070212; GO:0000209; GO:0015031; GO:0000922; GO:0008270,"Golgi apparatus; Golgi membrane; NAD+ ADP-ribosyltransferase activity; Wnt receptor signaling pathway; cell division; chromosome, centromeric region; mRNA transport; mitosis; negative regulation of DNA binding; nuclear chromosome, telomeric region; nuclear pore; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of telomere maintenance via telomerase; positive regulation of transcription from RNA polymerase II promoter; protein auto-ADP-ribosylation; protein localization to chromosome, telomeric region; protein poly-ADP-ribosylation; protein polyubiquitination; protein transport; spindle pole; zinc ion binding",PF00023;PF12796;PF13606;PF00644;PF07647;,,,,,,,,,TNKS1_MOUSE,Mus musculus (Mouse),"cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]" comp76981_c0_seq1,334,41.3174,0.35189391,3,15,,1.00E-32,Q562D6,Nef-associated protein 1 (EC 3.1.2.-) (Thioesterase NAP1),tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O),GO:0016787,hydrolase activity,PF01980;,3.00E-24,CHOYP_NAP1.1.1,,,,,,,NAP1_MOUSE,Mus musculus (Mouse),tRNA methylation [GO:0030488] comp76987_c0_seq1,475,40.4211,0.88043041,10,7,,,,,,,,,5.00E-16,CHOYP_TBCD4.1.1,3.00E-49,ruditapes_c13854,,,,,,, comp76992_c0_seq1,412,44.6602,0.60153286,6,34,,2.00E-48,Q5F3L1,Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1),Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0043990; GO:0043987; GO:0043988; GO:0070498; GO:0007243; GO:0000287; GO:0045892; GO:0005634; GO:0051092; GO:0035066; GO:0033129; GO:0045944; GO:0004674; GO:0009605; GO:0006950,"ATP binding; cytoplasm; histone H2A-S1 phosphorylation; histone H3-S10 phosphorylation; histone H3-S28 phosphorylation; interleukin-1-mediated signaling pathway; intracellular protein kinase cascade; magnesium ion binding; negative regulation of transcription, DNA-dependent; nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of histone acetylation; positive regulation of histone phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein serine/threonine kinase activity; response to external stimulus; response to stress",PF00069;PF00433;,2.00E-27,CHOYP_KS6A5.1.1,,,,,,,KS6A5_CHICK,Gallus gallus (Chicken),histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; intracellular signal transduction [GO:0035556]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp76993_c0_seq1,440,44.3182,0.79468293,20,10,,3.00E-19,Q80TI0,GRAM domain-containing protein 1B,GRAM domain-containing protein 1B,GO:0016021,integral to membrane,PF16016;PF02893;,,,,,,,,,GRM1B_MOUSE,Mus musculus (Mouse), comp77022_c0_seq1,774,45.6072,0.58642682,40,46,,2.00E-47,Q9Y6R4,Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),GO:0005524; GO:0007254; GO:0004709; GO:0060718; GO:0005737; GO:0019100; GO:0046872; GO:0048471; GO:0001890; GO:0043507; GO:0010468,ATP binding; JNK cascade; MAP kinase kinase kinase activity; chorionic trophoblast cell differentiation; cytoplasm; male germ-line sex determination; metal ion binding; perinuclear region of cytoplasm; placenta development; positive regulation of JUN kinase activity; regulation of gene expression,PF00069;,6.00E-37,CHOYP_LOC101174856.1.1,,,,,,,M3K4_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] comp77022_c1_seq1,456,47.1491,0.52233415,12,20,,,,,,,,,2.00E-22,CHOYP_LOC101174856.1.1,,,,,,,,, comp77034_c0_seq1,221,60.181,1.11204463,1,15,,4.00E-44,Q6AB12,4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) (4-(phosphohydroxy)-L-threonine dehydrogenase),4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) (4-(phosphohydroxy)-L-threonine dehydrogenase),GO:0050570; GO:0051287; GO:0005737; GO:0046872; GO:0042823; GO:0008615,4-hydroxythreonine-4-phosphate dehydrogenase activity; NAD binding; cytoplasm; metal ion binding; pyridoxal phosphate biosynthetic process; pyridoxine biosynthetic process,PF04166;,,,,,,,,,PDXA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615] comp77055_c0_seq1,325,48.3077,0.70563439,24,0,,1.00E-16,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,,,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp77105_c1_seq1,362,45.8564,0.48436248,5,27,,7.00E-41,O45870,Putative neutral sphingomyelinase (EC 3.1.4.12),Putative neutral sphingomyelinase (EC 3.1.4.12),GO:0016021; GO:0046872; GO:0006665; GO:0004767,integral to membrane; metal ion binding; sphingolipid metabolic process; sphingomyelin phosphodiesterase activity,PF03372;,7.00E-19,CHOYP_LOC100878974.1.1,,,,,,,NSMA_CAEEL,Caenorhabditis elegans,sphingolipid metabolic process [GO:0006665] comp77113_c0_seq1,205,37.561,0.97434751,0,0,,6.00E-25,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp77147_c0_seq2,275,39.2727,0.80379658,0,17,,1.00E-06,P13608,Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP),Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,PGCA_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp77213_c0_seq1,323,45.2012,1.29232008,18,19,,2.00E-07,O15016,Tripartite motif-containing protein 66,Tripartite motif-containing protein 66,GO:0016235; GO:0005634; GO:0008270,aggresome; nucleus; zinc ion binding,PF00439;PF00628;PF00643;,,,,,,,,,TRI66_HUMAN,Homo sapiens (Human), comp77238_c0_seq1,500,57.6,0.82545397,2,41,,4.00E-50,D7GIS1,Cobalt transport protein CbiM (Energy-coupling factor transporter probable substrate-capture protein CbiM) (ECF transporter S component CbiM),Cobalt transport protein CbiM (Energy-coupling factor transporter probable substrate-capture protein CbiM) (ECF transporter S component CbiM),GO:0043190; GO:0009236; GO:0006824; GO:0016021; GO:0005886,ATP-binding cassette (ABC) transporter complex; cobalamin biosynthetic process; cobalt ion transport; integral to membrane; plasma membrane,PF01891;,,,,,,,,,CBIM_PROFC,Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1),cobalamin biosynthetic process [GO:0009236] comp77243_c0_seq1,431,44.5476,0.64648673,23,38,,1.00E-39,P31751,RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta),RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta),GO:0005524; GO:0032859; GO:0006915; GO:0008643; GO:0005938; GO:0005829; GO:0045444; GO:0006006; GO:0005978; GO:0008286; GO:0065002; GO:0030027; GO:0060644; GO:0010748; GO:0005634; GO:0032287; GO:0005543; GO:2000147; GO:0032000; GO:0046326; GO:2001275; GO:0045725; GO:0001934; GO:0090314; GO:0031340; GO:0072659; GO:0004674; GO:0046328; GO:0071156; GO:0030334; GO:0006417; GO:0032587,ATP binding; activation of Ral GTPase activity; apoptotic process; carbohydrate transport; cell cortex; cytosol; fat cell differentiation; glucose metabolic process; glycogen biosynthetic process; insulin receptor signaling pathway; intracellular protein transmembrane transport; lamellipodium; mammary gland epithelial cell differentiation; negative regulation of plasma membrane long-chain fatty acid transport; nucleus; peripheral nervous system myelin maintenance; phospholipid binding; positive regulation of cell motility; positive regulation of fatty acid beta-oxidation; positive regulation of glucose import; positive regulation of glucose import in response to insulin stimulus; positive regulation of glycogen biosynthetic process; positive regulation of protein phosphorylation; positive regulation of protein targeting to membrane; positive regulation of vesicle fusion; protein localization to plasma membrane; protein serine/threonine kinase activity; regulation of JNK cascade; regulation of cell cycle arrest; regulation of cell migration; regulation of translation; ruffle membrane,PF00169;PF00069;PF00433;,6.00E-34,CHOYP_AKT1.2.2,,,,,,,AKT2_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; cellular protein modification process [GO:0006464]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; fat cell differentiation [GO:0045444]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; insulin receptor signaling pathway [GO:0008286]; intracellular protein transmembrane transport [GO:0065002]; intracellular signal transduction [GO:0035556]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of plasma membrane long-chain fatty acid transport [GO:0010748]; negative regulation of RNA splicing [GO:0033119]; peptidyl-serine phosphorylation [GO:0018105]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of cell migration [GO:0030335]; positive regulation of cell motility [GO:2000147]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of signal transduction [GO:0009967]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vesicle fusion [GO:0031340]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of cell cycle arrest [GO:0071156]; regulation of cell migration [GO:0030334]; regulation of translation [GO:0006417]; response to muscle activity [GO:0014850]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165] comp77250_c0_seq1,341,41.6422,0.41371324,1,40,,1.00E-06,P33545,Desmocollin-2 (Epithelial type 2 desmocollin) (Fragment),Desmocollin-2 (Epithelial type 2 desmocollin) (Fragment),GO:0005509; GO:0030057; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; desmosome; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;PF08758;,,,,,,,,,DSC2_BOVIN,Bos taurus (Bovine),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp77255_c0_seq1,283,35.3357,0.45604744,10,5,,4.00E-10,Q6GQH4,Early growth response protein 1-A (EGR-1-A) (Xegr-1),Early growth response protein 1-A (EGR-1-A) (Xegr-1),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF11914;PF11928;,,,,,,,,,EGR1A_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp77276_c0_seq1,340,45.5882,0.62454753,0,42,,3.00E-13,Q00727,Putative sterigmatocystin biosynthesis dehydrogenase stcV (EC 1.1.1.-),Putative sterigmatocystin biosynthesis dehydrogenase stcV (EC 1.1.1.-),GO:1900560; GO:1900563; GO:0016491; GO:0045461,austinol biosynthetic process; dehydroaustinol biosynthetic process; oxidoreductase activity; sterigmatocystin biosynthetic process,PF00248;,,,,,,,,,STCV_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),sterigmatocystin biosynthetic process [GO:0045461] comp77283_c0_seq1,575,46.6087,0.48128488,38,3,,1.00E-54,Q8N8S7,Protein enabled homolog,Protein enabled homolog,GO:0050852; GO:0008154; GO:0007411; GO:0005829; GO:0030175; GO:0005925; GO:0046907; GO:0030027; GO:0001843; GO:0005886; GO:0001725; GO:0045202,T cell receptor signaling pathway; actin polymerization or depolymerization; axon guidance; cytosol; filopodium; focal adhesion; intracellular transport; lamellipodium; neural tube closure; plasma membrane; stress fiber; synapse,PF08776;PF00568;,1.00E-38,CHOYP_EVL.1.1,,,,,,,ENAH_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411] comp77291_c0_seq1,403,41.6873,0.40914604,5,30,,2.00E-58,Q99PV3,Muskelin,Muskelin,GO:0005737,cytoplasm,PF01344;PF06588;,8.00E-19,CHOYP_MKLN1.1.1,,,,,,,MKLN1_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360] comp77309_c1_seq1,554,34.296,0.53877132,11,44,,9.00E-65,Q64531,Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (HPRT A) (EC 2.4.2.8) (Fragment),Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (HPRT A) (EC 2.4.2.8) (Fragment),GO:0046038; GO:0046040; GO:0032264; GO:0007610; GO:0005737; GO:0052657; GO:0006178; GO:0004422; GO:0043103; GO:0000287; GO:0000166; GO:0045964; GO:0042803; GO:0051289; GO:0006164; GO:0006166,GMP catabolic process; IMP metabolic process; IMP salvage; behavior; cytoplasm; guanine phosphoribosyltransferase activity; guanine salvage; hypoxanthine phosphoribosyltransferase activity; hypoxanthine salvage; magnesium ion binding; nucleotide binding; positive regulation of dopamine metabolic process; protein homodimerization activity; protein homotetramerization; purine nucleotide biosynthetic process; purine ribonucleoside salvage,PF00156;,1.00E-74,CHOYP_HPRT.1.1,,,,,,,HPRT_MUSSP,Mus spretus (Western Mediterranean mouse) (Algerian mouse),adenine metabolic process [GO:0046083]; adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; cytolysis [GO:0019835]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; response to amphetamine [GO:0001975]; striatum development [GO:0021756] comp77330_c0_seq1,308,46.4286,0.24819539,1,18,,,,,,,,,6.00E-51,CHOYP_PHUM_PHUM293090.2.2,,,,,,,,, comp77330_c1_seq1,634,42.5868,0.27875399,16,57,,2.00E-48,Q641I1,Protein FAM135B,Protein FAM135B,,,PF12394;PF05057;,,,,,,,,,F135B_XENLA,Xenopus laevis (African clawed frog), comp77340_c1_seq1,242,49.5868,0.74333861,0,14,,3.00E-06,A7SMW7,"L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)","L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)",GO:0047545; GO:0005739,2-hydroxyglutarate dehydrogenase activity; mitochondrion,PF01266;,,,,,,,,,L2HDH_NEMVE,Nematostella vectensis (Starlet sea anemone), comp77369_c0_seq1,339,52.8024,0.85859333,1,20,,2.00E-16,P17985,Insertion element ISR1 uncharacterized 10 kDa protein A3,Insertion element ISR1 uncharacterized 10 kDa protein A3,GO:0003677; GO:0004803; GO:0006313,"DNA binding; transposase activity; transposition, DNA-mediated",PF01527;,,,,,,,,,YIA3_RHISP,Rhizobium sp.,"transposition, DNA-mediated [GO:0006313]" comp77379_c0_seq1,338,46.7456,0.54881491,13,32,,6.00E-58,Q9QXK7,Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73),Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73),GO:0008409; GO:0003723; GO:0004521; GO:0006398; GO:0005847; GO:0046872; GO:0030529,5'-3' exonuclease activity; RNA binding; endoribonuclease activity; histone mRNA 3'-end processing; mRNA cleavage and polyadenylation specificity factor complex; metal ion binding; ribonucleoprotein complex,PF10996;PF11718;PF00753;PF07521;,6.00E-58,CHOYP_BRAFLDRAFT_282200.1.1,,,,,,,CPSF3_MOUSE,Mus musculus (Mouse),mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398] comp77390_c0_seq1,243,43.6214,0.7011613,6,20,,2.00E-21,P32198,"Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)","Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)",GO:0004095; GO:0009437; GO:0071398; GO:0042755; GO:0006635; GO:0006006; GO:0042802; GO:0031307; GO:0001676; GO:0005743; GO:0032000; GO:0051260; GO:0050796; GO:0042493; GO:0014070; GO:0006810; GO:0006641,carnitine O-palmitoyltransferase activity; carnitine metabolic process; cellular response to fatty acid; eating behavior; fatty acid beta-oxidation; glucose metabolic process; identical protein binding; integral to mitochondrial outer membrane; long-chain fatty acid metabolic process; mitochondrial inner membrane; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic compound; transport; triglyceride metabolic process,PF00755;PF16484;,1.00E-19,CHOYP_LOC577934.1.1,,,,,,,CPT1A_RAT,Rattus norvegicus (Rat),carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641] comp77422_c0_seq1,519,46.0501,1.20209246,14,14,,2.00E-16,P16066,Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A),GO:0005524; GO:0008528; GO:0005525; GO:0007589; GO:0042417; GO:0004383; GO:0042562; GO:0005887; GO:0035556; GO:0016941; GO:0016525; GO:0030308; GO:0048662; GO:0017046; GO:0030828; GO:0035815; GO:0035810; GO:0004672; GO:0007168; GO:0008217; GO:0050880; GO:0043114; GO:0042312,ATP binding; G-protein coupled peptide receptor activity; GTP binding; body fluid secretion; dopamine metabolic process; guanylate cyclase activity; hormone binding; integral to plasma membrane; intracellular signal transduction; natriuretic peptide receptor activity; negative regulation of angiogenesis; negative regulation of cell growth; negative regulation of smooth muscle cell proliferation; peptide hormone binding; positive regulation of cGMP biosynthetic process; positive regulation of renal sodium excretion; positive regulation of urine volume; protein kinase activity; receptor guanylyl cyclase signaling pathway; regulation of blood pressure; regulation of blood vessel size; regulation of vascular permeability; regulation of vasodilation,PF01094;PF00211;PF07714;,,,,,,,,,ANPRA_HUMAN,Homo sapiens (Human),body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of cardiac conduction [GO:1903779]; regulation of vascular permeability [GO:0043114]; regulation of vasodilation [GO:0042312] comp77434_c0_seq1,504,50,0.9271958,7,20,,5.00E-22,Q80TF4,Kelch-like protein 13 (BTB and kelch domain-containing protein 2),Kelch-like protein 13 (BTB and kelch domain-containing protein 2),GO:0031463; GO:0000910; GO:0007067; GO:0016567,Cul3-RING ubiquitin ligase complex; cytokinesis; mitosis; protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH13_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp77443_c0_seq1,215,49.7674,0.45763702,3,9,,5.00E-18,Q8IZE3,Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3),Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3),GO:0005524; GO:0005794; GO:0016477; GO:0030027; GO:0006468; GO:0016772,"ATP binding; Golgi apparatus; cell migration; lamellipodium; protein phosphorylation; transferase activity, transferring phosphorus-containing groups",PF00069;,,,,,,,,,PACE1_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; protein phosphorylation [GO:0006468] comp77444_c0_seq1,210,40.9524,0.68470996,2,6,,8.00E-06,Q08D64,"ATP-binding cassette sub-family B member 6, mitochondrial","ATP-binding cassette sub-family B member 6, mitochondrial",GO:0005524; GO:0006200; GO:0042626; GO:0005794; GO:0005783; GO:0016021; GO:0005741; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; Golgi apparatus; endoplasmic reticulum; integral to membrane; mitochondrial outer membrane; plasma membrane",PF00664;PF00005;PF16185;,,,,,,,,,ABCB6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085] comp77466_c0_seq1,228,42.5439,0.19489737,3,5,,2.00E-15,P57770,"A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) (Fragment)","A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) (Fragment)",GO:0005739; GO:0005886; GO:0008104; GO:0038032,mitochondrion; plasma membrane; protein localization; termination of G-protein coupled receptor signaling pathway,PF00615;,,,,,,,,,AKA10_PIG,Sus scrofa (Pig),protein localization [GO:0008104] comp77467_c0_seq1,255,45.8824,0.54869184,4,16,,3.00E-06,Q6DGM8,Jun dimerization protein 2,Jun dimerization protein 2,GO:0005634; GO:0043565; GO:0003700; GO:0006351,"nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00170;,,,,,,,,,JDP2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"transcription, DNA-templated [GO:0006351]" comp77478_c0_seq1,331,44.1088,0.57628298,7,4,,4.00E-57,O75165,DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8),GO:0005765,lysosomal membrane,PF00226;PF14237;,3.00E-48,CHOYP_DJC13.1.1,,,,,,,DJC13_HUMAN,Homo sapiens (Human),endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] comp7748_c0_seq1,339,39.233,0.23776431,9,0,,,,,,,,,7.00E-13,CHOYP_LOC100891939.7.7,,,,,,,,, comp77494_c0_seq1,207,41.0628,0.23060405,1,5,,3.00E-11,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp77500_c0_seq1,215,39.5349,0.35881175,1,15,,5.00E-33,Q8IUH5,Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17),Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17),GO:0030660; GO:0016021; GO:0042953; GO:0015095; GO:0043123; GO:0018345; GO:0019706; GO:0004871; GO:0008270,Golgi-associated vesicle membrane; integral to membrane; lipoprotein transport; magnesium ion transmembrane transporter activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation; protein-cysteine S-palmitoyltransferase activity; signal transducer activity; zinc ion binding,PF12796;PF01529;,1.00E-18,CHOYP_ZDHHC17.1.1,,,,,,,ZDH17_HUMAN,Homo sapiens (Human),lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345] comp77527_c0_seq1,311,58.1994,1.26177775,0,13,,6.00E-33,P66004,Dihydrolipoyl dehydrogenase (LPD) (EC 1.8.1.4) (Component of peroxynitrite reductase/peroxidase complex) (Component of PNR/P) (Dihydrolipoamide dehydrogenase) (E3 component of alpha-ketoacid dehydrogenase complexes),,GO:0070404; GO:0016209; GO:0045454; GO:0005829; GO:0004148; GO:0015036; GO:0005576; GO:0050660; GO:0006096; GO:0040007; GO:0016655; GO:0009405; GO:0005886; GO:0045254; GO:0052572; GO:0006099,"NADH binding; antioxidant activity; cell redox homeostasis; cytosol; dihydrolipoyl dehydrogenase activity; disulfide oxidoreductase activity; extracellular region; flavin adenine dinucleotide binding; glycolysis; growth; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; pathogenesis; plasma membrane; pyruvate dehydrogenase complex; response to host immune response; tricarboxylic acid cycle",,,,,,,,,,DLDH_MYCTU,, comp77527_c1_seq1,255,60,1.14839585,2,6,,1.00E-21,P50970,Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes),Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes),GO:0045454; GO:0005737; GO:0004148; GO:0050660; GO:0006096,cell redox homeostasis; cytoplasm; dihydrolipoyl dehydrogenase activity; flavin adenine dinucleotide binding; glycolysis,PF07992;PF02852;,,,,,,,,,DLDH_ZYMMO,Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4),cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096] comp77542_c0_seq1,375,39.4667,0.42510195,3,59,,3.00E-51,Q8BUB4,WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain-containing protein 2),WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2),GO:0046872,metal ion binding,PF01363;PF00400;,4.00E-42,CHOYP_BRAFLDRAFT_70886.1.1,,,,,,,WDFY2_MOUSE,Mus musculus (Mouse),positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934] comp77545_c0_seq1,369,44.9864,0.72179402,3,8,,3.00E-19,Q8TCT0,Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4),Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4),GO:0005524; GO:0003951; GO:0001729; GO:0006672; GO:0005737; GO:0004143; GO:0006687; GO:0016021; GO:0000287; GO:0005739; GO:0005634; GO:0005543; GO:0005886; GO:0007205; GO:0044281,ATP binding; NAD+ kinase activity; ceramide kinase activity; ceramide metabolic process; cytoplasm; diacylglycerol kinase activity; glycosphingolipid metabolic process; integral to membrane; magnesium ion binding; mitochondrion; nucleus; phospholipid binding; plasma membrane; protein kinase C-activating G-protein coupled receptor signaling pathway; small molecule metabolic process,PF00781;,,,,,,,,,CERK1_HUMAN,Homo sapiens (Human),ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687] comp77553_c0_seq1,285,44.5614,0.57172118,14,0,,1.00E-06,Q93971,Transient receptor potential channel (Abnormal gonad development protein 2),Transient receptor potential channel (Abnormal gonad development protein 2),GO:0008324; GO:0030421; GO:0008406; GO:0016021; GO:0005216; GO:0007067; GO:0005886,cation transmembrane transporter activity; defecation; gonad development; integral to membrane; ion channel activity; mitosis; plasma membrane,PF00520;,,,,,,,,,TRPG_CAEEL,Caenorhabditis elegans,cation transport [GO:0006812]; defecation [GO:0030421]; gonad development [GO:0008406]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067] comp77566_c0_seq1,496,50,0.72315109,0,80,,2.00E-26,O94778,Aquaporin-8 (AQP-8),Aquaporin-8 (AQP-8),GO:0045177; GO:0015722; GO:0071320; GO:0005887; GO:0046691; GO:0043231; GO:0015250,apical part of cell; canalicular bile acid transport; cellular response to cAMP; integral to plasma membrane; intracellular canaliculus; intracellular membrane-bounded organelle; water channel activity,PF00230;,,,,,,,,,AQP8_HUMAN,Homo sapiens (Human),cellular response to cAMP [GO:0071320]; cellular water homeostasis [GO:0009992]; ion transmembrane transport [GO:0034220]; transport [GO:0006810]; water transport [GO:0006833] comp77602_c0_seq1,255,49.0196,0.9204045,0,41,,4.00E-16,Q9NL40,T-box protein 1 (T-brain) (Ap-TBR),T-box protein 1 (T-brain) (Ap-TBR),GO:0003677; GO:0005634; GO:0003700; GO:0006351,"DNA binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00907;,2.00E-12,CHOYP_TBR1.1.1,,,,,,,TBR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),"transcription, DNA-templated [GO:0006351]" comp77632_c0_seq1,235,40,0.96547203,4,0,,2.00E-19,P92523,Uncharacterized mitochondrial protein AtMg00860 (ORF158),Uncharacterized mitochondrial protein AtMg00860 (ORF158),GO:0005739,mitochondrion,,,,,,,,,,M860_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp77633_c0_seq1,393,42.2392,0.68992129,5,10,,9.00E-12,Q9R189,Protein unc-13 homolog D (Munc13-4),Protein unc-13 homolog D (Munc13-4),GO:0006887; GO:0005770; GO:0005764; GO:0016020; GO:0055037; GO:0046903,exocytosis; late endosome; lysosome; membrane; recycling endosome; secretion,PF00168;PF10540;,,,,,,,,,UN13D_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; secretion [GO:0046903] comp7764_c0_seq1,272,43.0147,1.03773332,1,3,,2.00E-07,Q9Y5X5,Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor),Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor),GO:0004930; GO:0015629; GO:0009582; GO:0005887; GO:0008188; GO:0007218; GO:0043408; GO:0045761; GO:2000479,G-protein coupled receptor activity; actin cytoskeleton; detection of abiotic stimulus; integral to plasma membrane; neuropeptide receptor activity; neuropeptide signaling pathway; regulation of MAPK cascade; regulation of adenylate cyclase activity; regulation of cAMP-dependent protein kinase activity,PF00001;,,,,,,,,,NPFF2_HUMAN,Homo sapiens (Human),cellular response to hormone stimulus [GO:0032870]; chemical synaptic transmission [GO:0007268]; detection of abiotic stimulus [GO:0009582]; G-protein coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408]; response to peptide [GO:1901652] comp77674_c0_seq1,323,45.2012,0.73014784,6,0,,8.00E-37,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,8.00E-12,CHOYP_LOC100374692.1.1,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp77680_c0_seq1,247,45.3441,1.21095735,3,7,,6.00E-13,P0CI71,Dyslexia-associated protein KIAA0319 homolog,Dyslexia-associated protein KIAA0319 homolog,GO:0031901; GO:0016021; GO:2000171; GO:0001764; GO:0005886,early endosome membrane; integral to membrane; negative regulation of dendrite development; neuron migration; plasma membrane,,,,,,,,,,K0319_RAT,Rattus norvegicus (Rat),negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764] comp77682_c1_seq1,255,44.3137,0.2406052,6,0,,2.00E-44,O17214,"Probable fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)","Probable fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)",GO:0004333; GO:0006106; GO:0005739; GO:0006099; GO:0045239,fumarate hydratase activity; fumarate metabolic process; mitochondrion; tricarboxylic acid cycle; tricarboxylic acid cycle enzyme complex,PF10415;PF00206;,1.00E-32,CHOYP_FUMH.2.2,,,,,,,FUMH_CAEEL,Caenorhabditis elegans,fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099] comp77722_c0_seq1,605,42.6446,0.70139081,10,52,,,,,,,,,1.00E-37,CHOYP_BRAFLDRAFT_71436.1.2,,,,,,,,, comp77755_c0_seq1,238,45.7983,0.40646976,4,12,,3.00E-14,Q13395,Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185),Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185),GO:0003723; GO:0001510; GO:0008173; GO:0006396; GO:0005634; GO:0006357,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing; nucleus; regulation of transcription from RNA polymerase II promoter,PF00588;,4.00E-20,CHOYP_LOC100700626.1.2,,,,,,,TARB1_HUMAN,Homo sapiens (Human),regulation of transcription from RNA polymerase II promoter [GO:0006357]; tRNA methylation [GO:0030488] comp77765_c0_seq2,573,46.0733,0.93009543,0,29,,1.00E-54,Q6DDL7,Protein unc-93 homolog A (Unc-93A),Protein unc-93 homolog A (Unc-93A),GO:0016021,integral to membrane,PF05978;,2.00E-40,CHOYP_UN93A.2.3,,,,,,,UN93A_XENLA,Xenopus laevis (African clawed frog), comp77766_c1_seq1,292,46.5753,0.51813163,8,12,,2.00E-25,P54098,DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha),DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha),GO:0003677; GO:0006261; GO:0003887; GO:0007568; GO:0006287; GO:0008219; GO:0003682; GO:0004527; GO:0005760; GO:0006264; GO:0005743; GO:0042645,"DNA binding; DNA-dependent DNA replication; DNA-directed DNA polymerase activity; aging; base-excision repair, gap-filling; cell death; chromatin binding; exonuclease activity; gamma DNA polymerase complex; mitochondrial DNA replication; mitochondrial inner membrane; mitochondrial nucleoid",PF00476;,,,,,,,,,DPOG1_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-dependent DNA replication [GO:0006261]; DNA metabolic process [GO:0006259]; mitochondrial DNA replication [GO:0006264]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416]" comp77797_c0_seq1,255,40.7843,0.6689166,8,5,,2.00E-16,O94911,ATP-binding cassette sub-family A member 8,ATP-binding cassette sub-family A member 8,GO:0005524; GO:0006200; GO:0016887; GO:0042626; GO:0016021; GO:0005743; GO:0005886,"ATP binding; ATP catabolic process; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; mitochondrial inner membrane; plasma membrane",PF00005;,,,,,,,,,ABCA8_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp77797_c1_seq1,302,45.6954,0.63978742,5,0,,4.00E-31,Q7TNJ2,ATP-binding cassette sub-family A member 7,ATP-binding cassette sub-family A member 7,GO:0005524; GO:0006200; GO:0016887; GO:0000139; GO:0010008; GO:0016021; GO:0006909; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; Golgi membrane; endosome membrane; integral to membrane; phagocytosis; plasma membrane,PF00005;,2.00E-24,CHOYP_ABCA3.5.6,,,,,,,ABCA7_RAT,Rattus norvegicus (Rat),apolipoprotein A-I-mediated signaling pathway [GO:0038027]; cholesterol efflux [GO:0033344]; high-density lipoprotein particle assembly [GO:0034380]; lipid transport [GO:0006869]; memory [GO:0007613]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of ATPase activity [GO:0032780]; negative regulation of beta-amyloid formation [GO:1902430]; peptide cross-linking [GO:0018149]; phagocytosis [GO:0006909]; phospholipid efflux [GO:0033700]; phospholipid scrambling [GO:0017121]; positive regulation of ATPase activity [GO:0032781]; positive regulation of beta-amyloid clearance [GO:1900223]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of engulfment of apoptotic cell [GO:1901076]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phospholipid efflux [GO:1902995]; protein localization to nucleus [GO:0034504] comp77842_c0_seq1,248,72.1774,1.18424954,0,16,,6.00E-16,P54721,"Catechol-2,3-dioxygenase (EC 1.13.11.2) (Catechol-induced ring cleavage extradiol dioxygenase)","Catechol-2,3-dioxygenase (EC 1.13.11.2) (Catechol-induced ring cleavage extradiol dioxygenase)",GO:0019439; GO:0018577; GO:0008198; GO:0009636,"aromatic compound catabolic process; catechol 2,3-dioxygenase activity; ferrous iron binding; response to toxic substance",PF00903;,,,,,,,,,CADE_BACSU,Bacillus subtilis (strain 168),aromatic compound catabolic process [GO:0019439]; response to toxic substance [GO:0009636] comp77878_c0_seq1,259,53.2819,1.05175083,11,7,,3.00E-07,Q9R001,A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (ADMP-2) (Aggrecanase-2) (Implantin),A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (ADMP-2) (Aggrecanase-2) (Implantin),GO:0005737; GO:0004222; GO:0008237; GO:0005634; GO:0005578; GO:0006508; GO:0008270,cytoplasm; metalloendopeptidase activity; metallopeptidase activity; nucleus; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF05986;PF01562;PF01421;PF00090;,,,,,,,,,ATS5_MOUSE,Mus musculus (Mouse),defense response to bacterium [GO:0042742] comp77894_c0_seq1,291,44.6735,0.62931778,5,28,,2.00E-25,O89032,SH3 and PX domain-containing protein 2A (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains),SH3 and PX domain-containing protein 2A (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains),GO:0007154; GO:0030054; GO:0042995; GO:0005737; GO:0035091; GO:0002102; GO:0072593,cell communication; cell junction; cell projection; cytoplasm; phosphatidylinositol binding; podosome; reactive oxygen species metabolic process,PF00787;PF00018;,,,,,,,,,SPD2A_MOUSE,Mus musculus (Mouse),osteoclast fusion [GO:0072675]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; reactive oxygen species metabolic process [GO:0072593]; superoxide metabolic process [GO:0006801] comp77910_c0_seq2,268,40.2985,0.56042447,2,0,,4.00E-16,P51798,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0005254; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; chloride channel activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,,,,,,,,,CLCN7_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810] comp77926_c0_seq1,387,33.5917,0.46015488,11,0,,,,,,,,,2.00E-20,CHOYP_SCHCODRAFT_237230.2.2,,,,,,,,, comp77933_c0_seq1,204,36.7647,0.2958224,4,0,,5.00E-07,Q5DRE1,Protocadherin alpha-C2 (PCDH-alpha-C2),Protocadherin alpha-C2 (PCDH-alpha-C2),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDC2_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] comp77953_c0_seq1,383,47.2585,0.70347329,7,19,,7.00E-25,O18956,Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39),Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39),GO:0005524; GO:0016787; GO:0016021,ATP binding; hydrolase activity; integral to membrane,PF01150;,,,,,,,,,ENTP1_BOVIN,Bos taurus (Bovine), comp78016_c0_seq1,526,41.0646,0.55015423,11,13,,6.00E-40,Q9C0D9,Ethanolaminephosphotransferase 1 (hEPT1) (EC 2.7.8.1) (Selenoprotein I) (SelI),Ethanolaminephosphotransferase 1 (hEPT1) (EC 2.7.8.1) (Selenoprotein I) (SelI),GO:0005789; GO:0004307; GO:0016021; GO:0046872; GO:0006646; GO:0044281,endoplasmic reticulum membrane; ethanolaminephosphotransferase activity; integral to membrane; metal ion binding; phosphatidylethanolamine biosynthetic process; small molecule metabolic process,PF01066;,1.00E-30,CHOYP_BRAFLDRAFT_123523.1.1,,,,,,,EPT1_HUMAN,Homo sapiens (Human),phosphatidylethanolamine biosynthetic process [GO:0006646]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp78016_c1_seq1,221,43.8914,0.47315547,1,0,,2.00E-09,Q550W1,Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 3 (Developmental gene 1056 protein),Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 3 (Developmental gene 1056 protein),GO:0016021; GO:0008654; GO:0016780,"integral to membrane; phospholipid biosynthetic process; phosphotransferase activity, for other substituted phosphate groups",PF01066;,,,,,,,,,CAPTC_DICDI,Dictyostelium discoideum (Slime mold),phospholipid biosynthetic process [GO:0008654] comp78022_c0_seq1,233,67.382,1.17838428,0,18,,6.00E-48,B9MH63,Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase),Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase),GO:0055129; GO:0050661; GO:0005737; GO:0004350,L-proline biosynthetic process; NADP binding; cytoplasm; glutamate-5-semialdehyde dehydrogenase activity,PF00171;,,,,,,,,,PROA_ACIET,Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)),L-proline biosynthetic process [GO:0055129] comp78022_c1_seq1,224,62.9464,1.00576717,0,2,,6.00E-10,P0A2J9,Trk system potassium uptake protein TrkA (K(+)-uptake protein TrkA),Trk system potassium uptake protein TrkA (K(+)-uptake protein TrkA),GO:0005886; GO:0071805; GO:0015079,plasma membrane; potassium ion transmembrane transport; potassium ion transmembrane transporter activity,PF02080;PF02254;,,,,,,,,,TRKA_SALTY,Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720),secondary metabolite biosynthetic process [GO:0044550] comp78023_c0_seq1,423,50.3546,0.48624125,11,5,,7.00E-28,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,3.00E-31,CHOYP_LOC577371.1.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp78061_c0_seq1,354,48.0226,0.54048874,12,24,,6.00E-32,Q9WTQ1,Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu),Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu),GO:0005524; GO:0005794; GO:0007030; GO:0048193; GO:0001525; GO:0006915; GO:0005938; GO:0005911; GO:0034599; GO:0035924; GO:0005829; GO:0006954; GO:0045087; GO:0007243; GO:0035556; GO:0046872; GO:0060548; GO:0005634; GO:0018105; GO:0005543; GO:0005886; GO:0032793; GO:0043123; GO:0051092; GO:0045766; GO:0043536; GO:0038033; GO:0010595; GO:0001938; GO:1901727; GO:0010976; GO:0045669; GO:0033138; GO:0045944; GO:0004697; GO:0004674; GO:0010837; GO:0005802,ATP binding; Golgi apparatus; Golgi organization; Golgi vesicle transport; angiogenesis; apoptotic process; cell cortex; cell-cell junction; cellular response to oxidative stress; cellular response to vascular endothelial growth factor stimulus; cytosol; inflammatory response; innate immune response; intracellular protein kinase cascade; intracellular signal transduction; metal ion binding; negative regulation of cell death; nucleus; peptidyl-serine phosphorylation; phospholipid binding; plasma membrane; positive regulation of CREB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of histone deacetylase activity; positive regulation of neuron projection development; positive regulation of osteoblast differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein kinase C activity; protein serine/threonine kinase activity; regulation of keratinocyte proliferation; trans-Golgi network,PF00130;PF00169;PF00069;,8.00E-31,CHOYP_KPCD3.1.1,,,,,,,KPCD1_RAT,Rattus norvegicus (Rat),angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of cell death [GO:0060548]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; Ras protein signal transduction [GO:0007265]; regulation of keratinocyte proliferation [GO:0010837]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279] comp78074_c0_seq1,280,41.0714,0.69170113,4,1,,3.00E-16,Q86XU0,Zinc finger protein 677,Zinc finger protein 677,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN677_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp78103_c0_seq1,271,44.6494,0.30072272,4,2,,1.00E-36,Q8TD22,Sideroflexin-5,Sideroflexin-5,GO:0008324; GO:0015137; GO:0016021; GO:0055072; GO:0005743,cation transmembrane transporter activity; citrate transmembrane transporter activity; integral to membrane; iron ion homeostasis; mitochondrial inner membrane,PF03820;,3.00E-15,CHOYP_SFXN5.1.1,,,,,,,SFXN5_HUMAN,Homo sapiens (Human),iron ion homeostasis [GO:0055072] comp78105_c0_seq1,391,45.7801,0.72306138,8,8,,4.00E-36,P68827,N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase),N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase),GO:0032580; GO:0003944; GO:0016021; GO:0006486,Golgi cisterna membrane; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity; integral to membrane; protein glycosylation,PF09992;,,,,,,,,,NAGPA_BOVIN,Bos taurus (Bovine),protein glycosylation [GO:0006486] comp78112_c1_seq1,314,44.9045,1.01532053,5,5,,4.00E-21,P14943,Liver carboxylesterase 2 (EC 3.1.1.1),Liver carboxylesterase 2 (EC 3.1.1.1),GO:0004091; GO:0005788,carboxylesterase activity; endoplasmic reticulum lumen,PF00135;,,,,,,,,,EST2_RABIT,Oryctolagus cuniculus (Rabbit), comp78117_c0_seq1,352,46.875,0.37024572,14,0,,1.00E-15,O94759,Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7),Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7),GO:0047631; GO:0005262; GO:0005887; GO:0005384; GO:0033194; GO:0005272; GO:0035725,ADP-ribose diphosphatase activity; calcium channel activity; integral to plasma membrane; manganese ion transmembrane transporter activity; response to hydroperoxide; sodium channel activity; sodium ion transmembrane transport,PF00520;,,,,,,,,,TRPM2_HUMAN,Homo sapiens (Human),calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; estrous cycle [GO:0044849]; positive regulation of insulin secretion [GO:0032024]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; response to oxidative stress [GO:0006979] comp78123_c0_seq1,201,60.199,0.94342995,3,0,,6.00E-18,O06476,Uncharacterized ABC transporter ATP-binding protein YfmR (EC 3.6.3.-),Uncharacterized ABC transporter ATP-binding protein YfmR (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; transport,PF00005;PF16326;PF12848;,,,,,,,,,YFMR_BACSU,Bacillus subtilis (strain 168),transport [GO:0006810] comp78138_c0_seq2,264,37.5,0.33015424,1,11,,3.00E-06,Q66J54,Solute carrier family 22 member 6-A (Organic cation transporter 1-A) (Renal organic anion transporter 1-A) (ROAT1-A),Solute carrier family 22 member 6-A (Organic cation transporter 1-A) (Renal organic anion transporter 1-A) (ROAT1-A),GO:0016021; GO:0015075; GO:0005886,integral to membrane; ion transmembrane transporter activity; plasma membrane,PF00083;,,,,,,,,,S226A_XENLA,Xenopus laevis (African clawed frog), comp78173_c0_seq1,549,35.7013,0.4019222,20,16,,5.00E-17,Q01791,Protein hunchback,Protein hunchback,GO:0003677; GO:0046872; GO:0005634; GO:0040034; GO:0035282; GO:0000981; GO:0006366,"DNA binding; metal ion binding; nucleus; regulation of development, heterochronic; segmentation; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription from RNA polymerase II promoter",,2.00E-29,CHOYP_HB.1.1,,,,,,,HUNB_TRICA,Tribolium castaneum (Red flour beetle),"regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]" comp78200_c0_seq1,284,42.2535,0.7925571,4,10,,3.00E-20,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,,,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp78226_c0_seq1,249,59.4378,1.2792604,1,2,,6.00E-51,Q6A651,"Putative pyruvate, phosphate dikinase regulatory protein (PPDK regulatory protein) (EC 2.7.11.32) (EC 2.7.4.27)","Putative pyruvate, phosphate dikinase regulatory protein (PPDK regulatory protein) (EC 2.7.11.32) (EC 2.7.4.27)",GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF03618;,,,,,,,,,PDRP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),protein dephosphorylation [GO:0006470] comp78374_c0_seq1,618,46.6019,0.53826228,24,11,,7.00E-76,Q5RD33,Amyloid beta A4 precursor protein-binding family A member 2,Amyloid beta A4 precursor protein-binding family A member 2,GO:0015031,protein transport,PF00595;PF00640;,2.00E-93,CHOYP_LOC100868101.1.1,,,,,,,APBA2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),chemical synaptic transmission [GO:0007268]; protein transport [GO:0015031] comp78402_c0_seq1,270,43.7037,0.79706976,4,17,,4.00E-09,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp78418_c0_seq1,208,61.0577,1.09399338,2,4,,1.00E-15,Q6AHF2,Ferrochelatase (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase),Ferrochelatase (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase),GO:0005737; GO:0004325; GO:0006783; GO:0046872,cytoplasm; ferrochelatase activity; heme biosynthetic process; metal ion binding,PF00762;,,,,,,,,,HEMH_LEIXX,Leifsonia xyli subsp. xyli (strain CTCB07),heme biosynthetic process [GO:0006783] comp78454_c0_seq1,275,61.4545,1.29193198,1,2,,2.00E-21,P46392,Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase (EC 6.3.4.14); Biotin carboxyl carrier protein (BCCP)],Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase (EC 6.3.4.14); Biotin carboxyl carrier protein (BCCP)],GO:0005524; GO:0004075; GO:0006633; GO:0046872,ATP binding; biotin carboxylase activity; fatty acid biosynthetic process; metal ion binding,PF02785;PF00289;PF00364;PF02786;,,,,,,,,,BCCA_MYCLE,Mycobacterium leprae (strain TN),fatty acid biosynthetic process [GO:0006633] comp78469_c0_seq1,426,36.385,0.42671787,11,0,,,,,,,,,3.00E-12,CHOYP_contig_006627,,,,,,,,, comp78475_c0_seq1,399,42.1053,0.46143044,5,45,,3.00E-19,Q4R8E0,Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Hemin-sensitive initiation factor 2-alpha kinase),Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Hemin-sensitive initiation factor 2-alpha kinase),GO:0005524; GO:0005737; GO:0017148; GO:0004674,ATP binding; cytoplasm; negative regulation of translation; protein serine/threonine kinase activity,PF00069;,,,,,,,,,E2AK1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),negative regulation of translation [GO:0017148] comp78507_c0_seq1,299,38.4615,0.46382708,7,5,,4.00E-23,Q8TF76,Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase),Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase),GO:0005524; GO:0003677; GO:0005813; GO:0005694; GO:0005737; GO:2000751; GO:0072354; GO:0007243; GO:0007064; GO:0031965; GO:0071459; GO:0090231; GO:0005819,"ATP binding; DNA binding; centrosome; chromosome; cytoplasm; histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; histone kinase activity (H3-T3 specific); intracellular protein kinase cascade; mitotic sister chromatid cohesion; nuclear membrane; protein localization to chromosome, centromeric region; regulation of spindle checkpoint; spindle",PF12330;,,,,,,,,,HASP_HUMAN,Homo sapiens (Human),"histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore [GO:2000751]; intracellular signal transduction [GO:0035556]; mitotic sister chromatid cohesion [GO:0007064]; protein localization to chromosome, centromeric region [GO:0071459]; protein phosphorylation [GO:0006468]; regulation of spindle checkpoint [GO:0090231]" comp78532_c0_seq1,524,47.3282,0.45237787,41,29,,7.00E-37,Q9Y4D2,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0008219; GO:0046340; GO:0071926; GO:0016021; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0030168; GO:0004806,arachidonic acid metabolic process; cell death; diacylglycerol catabolic process; endocannabinoid signaling pathway; integral to membrane; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; platelet activation; triglyceride lipase activity,PF01764;,7.00E-28,CHOYP_INAE.1.1,,,,,,,DGLA_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136] comp78557_c0_seq1,531,42.5612,0.46006452,13,19,,6.00E-16,Q6PAJ1,Breakpoint cluster region protein (EC 2.7.11.1),Breakpoint cluster region protein (EC 2.7.11.1),GO:0005524; GO:0030675; GO:0005089; GO:0030036; GO:0007420; GO:0005829; GO:0042472; GO:0035556; GO:0030336; GO:0050728; GO:0043314; GO:0050885; GO:0005543; GO:0005886; GO:0050766; GO:0004674; GO:0051726; GO:0032496,ATP binding; Rac GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; brain development; cytosol; inner ear morphogenesis; intracellular signal transduction; negative regulation of cell migration; negative regulation of inflammatory response; negative regulation of neutrophil degranulation; neuromuscular process controlling balance; phospholipid binding; plasma membrane; positive regulation of phagocytosis; protein serine/threonine kinase activity; regulation of cell cycle; response to lipopolysaccharide,PF09036;PF00168;PF00620;PF00621;,,,,,,,,,BCR_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496] comp78590_c0_seq1,328,41.4634,0.57935824,2,43,,7.00E-10,Q14315,Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),GO:0030018; GO:0034329; GO:0043034; GO:0005856; GO:0005829; GO:0048747; GO:0042383; GO:0016528,Z disc; cell junction assembly; costamere; cytoskeleton; cytosol; muscle fiber development; sarcolemma; sarcoplasm,PF00307;PF00630;,,,,,,,,,FLNC_HUMAN,Homo sapiens (Human),cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747] comp78609_c0_seq1,208,53.8462,0.77487467,5,0,,1.00E-10,Q7N3A6,Lipoprotein-releasing system ATP-binding protein LolD (EC 3.6.3.-),Lipoprotein-releasing system ATP-binding protein LolD (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0042954; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; lipoprotein transporter activity; plasma membrane,PF00005;,,,,,,,,,LOLD_PHOLL,Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01), comp78619_c0_seq1,259,32.4324,0.45481728,3,0,,,,,,,,,3.00E-16,CHOYP_CHGG_05501.1.1,,,,,,,,, comp78621_c0_seq1,364,63.1868,1.01319293,2,12,,5.00E-24,P68908,Uncharacterized protein Mb2921c,Uncharacterized protein Mb2921c,GO:0015995; GO:0016851; GO:0017111; GO:0000166; GO:0015979,chlorophyll biosynthetic process; magnesium chelatase activity; nucleoside-triphosphatase activity; nucleotide binding; photosynthesis,PF01078;PF13335;,,,,,,,,,Y2921_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp78621_c1_seq1,221,61.991,0.91657678,0,23,,4.00E-13,P68908,Uncharacterized protein Mb2921c,Uncharacterized protein Mb2921c,GO:0015995; GO:0016851; GO:0017111; GO:0000166; GO:0015979,chlorophyll biosynthetic process; magnesium chelatase activity; nucleoside-triphosphatase activity; nucleotide binding; photosynthesis,PF01078;PF13335;,,,,,,,,,Y2921_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp78660_c0_seq1,248,62.5,0.79970874,0,4,,5.00E-08,P41177,Monensin polyketide synthase putative ketoacyl reductase (EC 1.3.1.-) (ORF5),Monensin polyketide synthase putative ketoacyl reductase (EC 1.3.1.-) (ORF5),GO:0017000; GO:0016491,antibiotic biosynthetic process; oxidoreductase activity,PF00106;,,,,,,,,,DHKR_STRCM,Streptomyces cinnamonensis,antibiotic biosynthetic process [GO:0017000] comp78679_c0_seq1,563,45.1155,0.7004493,16,32,,3.00E-06,Q9UDY8,Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase),Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase),GO:0001923; GO:0032449; GO:0038095; GO:0042098; GO:0050852; GO:0007250; GO:0004197; GO:0005829; GO:0045087; GO:0043066; GO:0051168; GO:0005634; GO:0048471; GO:0005886; GO:0043123; GO:0051092; GO:0050870; GO:0002726; GO:0032743; GO:0031398; GO:0051259; GO:0006508; GO:0050856; GO:0009620; GO:0002237; GO:0004871; GO:0004842,B-1 B cell differentiation; CBM complex; Fc-epsilon receptor signaling pathway; T cell proliferation; T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; cysteine-type endopeptidase activity; cytosol; innate immune response; negative regulation of apoptotic process; nuclear export; nucleus; perinuclear region of cytoplasm; plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; positive regulation of T cell cytokine production; positive regulation of interleukin-2 production; positive regulation of protein ubiquitination; protein oligomerization; proteolysis; regulation of T cell receptor signaling pathway; response to fungus; response to molecule of bacterial origin; signal transducer activity; ubiquitin-protein ligase activity,PF13895;,,,,,,,,,MALT1_HUMAN,Homo sapiens (Human),activation of NF-kappaB-inducing kinase activity [GO:0007250]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; protein oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; response to molecule of bacterial origin [GO:0002237]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] comp78731_c1_seq1,331,39.577,0.46499024,4,26,,,,,,,,,,,3.00E-14,ruditapes_c13464,,,,,,, comp78731_c2_seq1,321,44.8598,0.62415802,10,9,,4.00E-23,C0HBT3,E3 ubiquitin-protein ligase rnf146 (EC 6.3.2.-) (RING finger protein 146),E3 ubiquitin-protein ligase rnf146 (EC 6.3.2.-) (RING finger protein 146),GO:0016055; GO:0005829; GO:0005634; GO:0072572; GO:0090263; GO:0070936; GO:0051865; GO:0042787; GO:0004842; GO:0008270,Wnt receptor signaling pathway; cytosol; nucleus; poly-ADP-D-ribose binding; positive regulation of canonical Wnt receptor signaling pathway; protein K48-linked ubiquitination; protein autoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02825;,2.00E-18,CHOYP_ND5.2.6,,,,,,,RN146_SALSA,Salmo salar (Atlantic salmon),positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; Wnt signaling pathway [GO:0016055] comp78754_c0_seq2,505,42.1782,0.45709303,17,14,,6.00E-31,Q9DAM5,Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19),Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19),GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,,,,,,,,,TPC_MOUSE,Mus musculus (Mouse),positive regulation of defense response to virus by host [GO:0002230]; translation [GO:0006412]; transmembrane transport [GO:0055085]; xenophagy [GO:0098792] comp78768_c0_seq1,225,43.1111,0.88053687,0,0,,3.00E-08,O62787,"Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3) (Fragment)","Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3) (Fragment)",GO:0008643; GO:0016021; GO:0022857,carbohydrate transport; integral to membrane; transmembrane transporter activity,PF00083;,5.00E-25,CHOYP_GTR1.1.1,,,,,,,GTR3_PIG,Sus scrofa (Pig),glucose transmembrane transport [GO:1904659] comp78768_c0_seq2,306,42.8105,1.01178105,5,7,,1.00E-14,Q8IRI6,Glucose transporter type 1,Glucose transporter type 1,GO:0008643; GO:0016021; GO:0022891,carbohydrate transport; integral to membrane; substrate-specific transmembrane transporter activity,PF00083;,,,,,,,,,GTR1_DROME,Drosophila melanogaster (Fruit fly),adult chitin-containing cuticle pigmentation [GO:0048085]; positive regulation of peptide hormone secretion [GO:0090277]; sensory perception of pain [GO:0019233] comp78789_c0_seq1,507,37.8698,0.60871697,4,0,,2.00E-08,P20645,Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46),Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46),GO:0009986; GO:0005768; GO:0008333; GO:0005887; GO:0005770; GO:0005765; GO:0005537; GO:0015578; GO:0006898; GO:0004888,cell surface; endosome; endosome to lysosome transport; integral to plasma membrane; late endosome; lysosomal membrane; mannose binding; mannose transmembrane transporter activity; receptor-mediated endocytosis; transmembrane signaling receptor activity,PF02157;,,,,,,,,,MPRD_HUMAN,Homo sapiens (Human),endosome to lysosome transport [GO:0008333]; receptor-mediated endocytosis [GO:0006898] comp78834_c0_seq1,315,44.4444,0.65574431,1,17,,1.00E-65,Q63487,Ras-related GTP-binding protein B (Rag B) (RagB),Ras-related GTP-binding protein B (Rag B) (RagB),GO:0005525; GO:0034613; GO:0071230; GO:0005764; GO:0005634; GO:0032008,GTP binding; cellular protein localization; cellular response to amino acid stimulus; lysosome; nucleus; positive regulation of TOR signaling cascade,PF04670;,3.00E-86,CHOYP_RRAGA.1.1,,,,,,,RRAGB_RAT,Rattus norvegicus (Rat),cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506] comp78841_c0_seq2,474,44.0928,0.65319323,8,13,,7.00E-21,Q8CAT8,F-box only protein 48,F-box only protein 48,,,PF12937;,,,,,,,,,FBX48_MOUSE,Mus musculus (Mouse), comp78844_c0_seq2,1339,38.2375,0.43026659,26,62,,2.00E-64,Q66JA6,45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4),45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4),GO:0005796; GO:0005509,Golgi lumen; calcium ion binding,PF13202;PF13499;,7.00E-26,CHOYP_CAB45.1.1,,,,,,,CAB45_XENLA,Xenopus laevis (African clawed frog), comp78864_c0_seq1,201,41.2935,1.31327128,0,6,,9.00E-25,Q8IXL6,Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi-enriched fraction casein kinase) (GEF-CK) (Protein FAM20C),Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi casein kinase) (Golgi-enriched fraction casein kinase) (GEF-CK),GO:0005509; GO:0097187; GO:0070166; GO:0005615; GO:0071895; GO:0036179; GO:0030501; GO:0045669; GO:0004674; GO:0040036; GO:0051174; GO:0001501,calcium ion binding; dentinogenesis; enamel mineralization; extracellular space; odontoblast differentiation; osteoclast maturation; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; protein serine/threonine kinase activity; regulation of fibroblast growth factor receptor signaling pathway; regulation of phosphorus metabolic process; skeletal system development,PF06702;,,,,,,,,,DMP4_HUMAN,Homo sapiens (Human),biomineral tissue development [GO:0031214]; dentinogenesis [GO:0097187]; enamel mineralization [GO:0070166]; odontoblast differentiation [GO:0071895]; osteoclast maturation [GO:0036179]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; protein phosphorylation [GO:0006468]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of phosphorus metabolic process [GO:0051174] comp78871_c0_seq1,249,40.9639,0.67386532,3,26,,2.00E-16,Q6DBQ8,Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP),Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP),GO:0005794; GO:1902387; GO:1902389; GO:1902388; GO:0005829; GO:0010008; GO:0051861; GO:0046836; GO:0017089; GO:0005640; GO:0005886,Golgi apparatus; ceramide 1-phosphate binding; ceramide 1-phosphate transport; ceramide 1-phosphate transporter activity; cytosol; endosome membrane; glycolipid binding; glycolipid transport; glycolipid transporter activity; nuclear outer membrane; plasma membrane,PF08718;,4.00E-14,CHOYP_DSIM_GD25210.1.1,,,,,,,GLTD1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ceramide 1-phosphate transport [GO:1902389] comp78903_c0_seq1,295,40,0.59954393,5,23,,,,,,,,,,,4.00E-12,ruditapes_c4344,,,,,,, comp78914_c0_seq1,363,46.832,0.9223043,2,8,,1.00E-34,O61397,Probable N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7),Probable N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7),GO:0000139; GO:0016021; GO:0006486; GO:0016757,"Golgi membrane; integral to membrane; protein glycosylation; transferase activity, transferring glycosyl groups",PF00535;PF00652;,2.00E-32,CHOYP_GALT9.1.1,,,,,,,GALT7_CAEEL,Caenorhabditis elegans,protein glycosylation [GO:0006486] comp78928_c0_seq1,272,52.9412,0.53165276,7,6,,7.00E-06,Q10925,Tyrosine-protein kinase sid-3 (EC 2.7.10.2) (Systemic RNA interference defective protein 3) (Systemic RNAi enabling protein),Tyrosine-protein kinase sid-3 (EC 2.7.10.2) (Systemic RNA interference defective protein 3) (Systemic RNAi enabling protein),GO:0005524; GO:0016246; GO:0005737; GO:0004715; GO:0018108,ATP binding; RNA interference; cytoplasm; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation,PF09027;PF07714;PF07653;,5.00E-19,CHOYP_TNK2.1.1,,,,,,,KIN25_CAEEL,Caenorhabditis elegans,cell differentiation [GO:0030154]; cell migration [GO:0016477]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell proliferation [GO:0042127]; RNA interference [GO:0016246]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp78932_c1_seq1,289,47.4048,0.92751644,10,11,,4.00E-17,Q14315,Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin),GO:0030018; GO:0034329; GO:0043034; GO:0005856; GO:0005829; GO:0048747; GO:0042383; GO:0016528,Z disc; cell junction assembly; costamere; cytoskeleton; cytosol; muscle fiber development; sarcolemma; sarcoplasm,PF00307;PF00630;,,,,,,,,,FLNC_HUMAN,Homo sapiens (Human),cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747] comp78977_c0_seq1,388,44.8454,0.67131735,6,16,,,,,,,,,2.00E-20,CHOYP_LOC100377600.2.2,,,,,,,,, comp79027_c0_seq1,344,38.3721,0,0,47,,2.00E-06,O61309,Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS),Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS),GO:0010181; GO:0050661; GO:0050660; GO:0020037; GO:0005506; GO:0006809; GO:0004517,FMN binding; NADP binding; flavin adenine dinucleotide binding; heme binding; iron ion binding; nitric oxide biosynthetic process; nitric-oxide synthase activity,PF00667;PF00258;PF00175;PF02898;,,,,,,,,,NOS_LYMST,Lymnaea stagnalis (Great pond snail) (Helix stagnalis),nitric oxide biosynthetic process [GO:0006809] comp79028_c0_seq1,201,46.7662,0.54967347,5,0,,1.00E-27,Q60700,Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase),Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase),GO:0005524; GO:0007254; GO:0004709; GO:0030424; GO:0005829; GO:0030426; GO:0016572; GO:0018105; GO:0018107; GO:0005886; GO:0046777; GO:0042803; GO:0004674,ATP binding; JNK cascade; MAP kinase kinase kinase activity; axon; cytosol; growth cone; histone phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; plasma membrane; protein autophosphorylation; protein homodimerization activity; protein serine/threonine kinase activity,PF07714;,9.00E-21,CHOYP_LOC590385.1.1,,,,,,,M3K12_MOUSE,Mus musculus (Mouse),histone phosphorylation [GO:0016572]; JNK cascade [GO:0007254]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of motor neuron apoptotic process [GO:2000672]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] comp79032_c0_seq1,316,45.8861,0.37294491,9,0,,,,,,,,,1.00E-33,CHOYP_LOC100649375.1.1,,,,,,,,, comp79033_c0_seq1,269,35.6877,0.47059474,5,8,,,,,,,,,5.00E-13,CHOYP_LOC100370465.2.2,,,,,,,,, comp7905_c0_seq1,303,44.2244,0.81429458,9,0,,3.00E-14,Q5HZQ9,Pecanex-like protein 4,Pecanex-like protein 4 (Pecanex homolog protein 4),GO:0016021,integral to membrane,PF05041;,,,,,,,,,PCX4_XENLA,Xenopus laevis (African clawed frog), comp79072_c0_seq1,1099,46.6788,0.33633,56,5,,7.00E-53,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,8.00E-18,CHOYP_BRAFLDRAFT_119774.3.4,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp79074_c0_seq2,429,39.1608,0.43877789,0,0,,4.00E-29,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,8.00E-26,CHOYP_LOC580404.1.3,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp79093_c0_seq1,566,48.0565,0.37125668,22,29,,3.00E-36,Q9HBZ2,Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1),Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1),GO:0003677; GO:0017162; GO:0007417; GO:0005737; GO:0001701; GO:0043066; GO:0005634; GO:0008284; GO:0045944; GO:0045893; GO:0046982; GO:0032355; GO:0001666; GO:0003700; GO:0004871; GO:0005667; GO:0006351,"DNA binding; aryl hydrocarbon receptor binding; central nervous system development; cytoplasm; in utero embryonic development; negative regulation of apoptotic process; nucleus; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein heterodimerization activity; response to estradiol stimulus; response to hypoxia; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor complex; transcription, DNA-dependent",PF00010;PF00989;PF08447;,1.00E-44,CHOYP_ARNT.1.1,,,,,,,ARNT2_HUMAN,Homo sapiens (Human),"brain development [GO:0007420]; central nervous system development [GO:0007417]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]" comp79104_c0_seq1,224,59.8214,1.35817596,0,27,,3.00E-20,O34618,Uncharacterized amino acid permease YtnA,Uncharacterized amino acid permease YtnA,GO:0015171; GO:0016021; GO:0005886,amino acid transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,YTNA_BACSU,Bacillus subtilis (strain 168), comp7911_c0_seq1,227,40.5286,0.54520427,2,0,,5.00E-23,Q801S4,Uncharacterized protein KIAA0930 homolog,Uncharacterized protein KIAA0930 homolog,,,PF09741;,,,,,,,,,K0930_XENLA,Xenopus laevis (African clawed frog), comp79145_c0_seq1,264,44.3182,0.46628235,0,24,,1.00E-08,E1BZ85,Meiosis arrest female protein 1 homolog (Limkain-b1),Meiosis arrest female protein 1 homolog (Limkain-b1),GO:0003723; GO:0010923; GO:0000166; GO:0048477; GO:0005777; GO:0010468,RNA binding; negative regulation of phosphatase activity; nucleotide binding; oogenesis; peroxisome; regulation of gene expression,PF11608;PF01936;PF12872;,1.00E-26,CHOYP_MARF1.1.1,,,,,,,MARF1_CHICK,Gallus gallus (Chicken),meiotic cell cycle [GO:0051321]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] comp79150_c0_seq1,293,43.3447,0,5,15,,7.00E-30,A3KPA3,N-alpha-acetyltransferase 60 (EC 2.3.1.48) (EC 2.3.1.88) (N-acetyltransferase 15) (NatF catalytic subunit),N-alpha-acetyltransferase 60 (EC 2.3.1.48) (EC 2.3.1.88) (N-acetyltransferase 15) (NatF catalytic subunit),GO:0000139; GO:0010485; GO:0017196; GO:0008283; GO:0007059; GO:0006334; GO:0004596,Golgi membrane; H4 histone acetyltransferase activity; N-terminal peptidyl-methionine acetylation; cell proliferation; chromosome segregation; nucleosome assembly; peptide alpha-N-acetyltransferase activity,PF00583;,2.00E-25,CHOYP_BRAFLDRAFT_225211.1.1,,,,,,,NAA60_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell proliferation [GO:0008283]; chromosome segregation [GO:0007059]; histone H4 acetylation [GO:0043967]; N-terminal peptidyl-methionine acetylation [GO:0017196]; nucleosome assembly [GO:0006334] comp79159_c0_seq1,894,43.5123,0.74248113,23,45,,2.00E-58,Q5R685,Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha),GO:0005942; GO:0035014; GO:0043551; GO:0007165,phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity; signal transduction,PF16454;PF00620;PF00017;,,,,,,,,,P85A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165] comp79163_c0_seq1,644,34.3168,1.24267346,27,3,,9.00E-07,Q9JKQ2,Prestin (Solute carrier family 26 member 5),Prestin (Solute carrier family 26 member 5),GO:0016323; GO:0016021; GO:0008360; GO:0008271; GO:0007605; GO:0008272,basolateral plasma membrane; integral to membrane; regulation of cell shape; secondary active sulfate transmembrane transporter activity; sensory perception of sound; sulfate transport,PF01740;PF00916;,,,,,,,,,S26A5_MERUN,Meriones unguiculatus (Mongolian jird) (Mongolian gerbil),regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605] comp79187_c0_seq1,282,40.7801,1.23969018,5,6,,,,,,,,,2.00E-11,CHOYP_contig_031422,,,,,,,,, comp79195_c0_seq1,310,35.8065,0.40654018,6,7,,2.00E-15,Q5RBY9,Zinc finger protein 2,Zinc finger protein 2,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13465;,,,,,,,,,ZNF2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp79204_c0_seq1,379,36.9393,0.63612077,19,28,,5.00E-57,Q9ULJ7,Ankyrin repeat domain-containing protein 50,Ankyrin repeat domain-containing protein 50,,,PF00023;PF12796;,3.00E-55,CHOYP_LOC100369716.1.1,,,,,,,ANR50_HUMAN,Homo sapiens (Human),"protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]" comp79205_c0_seq1,248,42.7419,0.2674587,3,12,,9.00E-29,Q9D711,"Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase)","Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase)",GO:0005737; GO:0046872; GO:0030224; GO:0005634; GO:0008127; GO:0006355; GO:0003712; GO:0006351,"cytoplasm; metal ion binding; monocyte differentiation; nucleus; quercetin 2,3-dioxygenase activity; regulation of transcription, DNA-dependent; transcription cofactor activity; transcription, DNA-dependent",PF02678;PF05726;,2.00E-29,CHOYP_PIR.1.1,,,,,,,PIR_MOUSE,Mus musculus (Mouse),"monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp79205_c1_seq1,285,46.3158,0.28373365,2,18,,1.00E-28,Q9SEE4,Pirin-like protein,Pirin-like protein,GO:0005634,nucleus,PF02678;PF05726;,,,,,,,,,PIRL_SOLLC,Solanum lycopersicum (Tomato) (Lycopersicon esculentum), comp79240_c0_seq1,339,52.2124,1.21553662,3,10,,,,,,,,,1.00E-10,CHOYP_LOC100908993.1.1,,,,,,,,, comp79253_c0_seq1,1149,39.2515,0.49157341,43,108,,3.00E-76,Q5RD03,Armadillo repeat-containing protein 6,Armadillo repeat-containing protein 6,,,PF00514;,,,,,,,,,ARMC6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp79253_c1_seq1,440,43.6364,0.44635858,20,44,,5.00E-26,Q8BNU0,Armadillo repeat-containing protein 6,Armadillo repeat-containing protein 6,,,PF00514;,,,,,,,,,ARMC6_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244] comp79256_c1_seq1,255,44.7059,1.10858494,1,15,,5.00E-15,Q7Z449,Cytochrome P450 2U1 (EC 1.14.14.1),Cytochrome P450 2U1 (EC 1.14.14.1),GO:0070330; GO:0008219; GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0097267; GO:0006805,aromatase activity; cell death; endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; omega-hydroxylase P450 pathway; xenobiotic metabolic process,PF00067;,,,,,,,,,CP2U1_HUMAN,Homo sapiens (Human),omega-hydroxylase P450 pathway [GO:0097267] comp79264_c0_seq1,232,48.7069,0.38072603,5,17,,4.00E-34,Q07075,Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249),GO:0001525; GO:0002005; GO:0002003; GO:0016324; GO:0005903; GO:0016477; GO:0008283; GO:0007267; GO:0044267; GO:0031410; GO:0009897; GO:0032835; GO:0005887; GO:0005765; GO:0070006; GO:0006508; GO:0008270,angiogenesis; angiotensin catabolic process in blood; angiotensin maturation; apical plasma membrane; brush border; cell migration; cell proliferation; cell-cell signaling; cellular protein metabolic process; cytoplasmic vesicle; external side of plasma membrane; glomerulus development; integral to plasma membrane; lysosomal membrane; metalloaminopeptidase activity; proteolysis; zinc ion binding,PF11838;PF01433;,7.00E-36,CHOYP_LOC409619.2.4,,,,,,,AMPE_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] comp79281_c0_seq1,403,36.9727,0.8068314,19,14,,3.00E-13,P09523,Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)],GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF02160;PF00078;,1.00E-36,CHOYP_LOC586954.1.1,,,,,,,POL_FMVD,Figwort mosaic virus (strain DxS) (FMV), comp79281_c1_seq1,477,41.2998,0.55080904,20,17,,1.00E-18,P20825,Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL2_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp79285_c0_seq1,225,41.7778,1.02310758,3,10,,2.00E-21,Q5T3U5,Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10),Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005765; GO:0005886; GO:0055085,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; lysosomal membrane; plasma membrane; transmembrane transport",PF00664;PF00005;,,,,,,,,,MRP7_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp79291_c0_seq1,222,44.5946,0.38120432,13,11,,5.00E-20,P14735,Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin),Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin),GO:0005524; GO:0016887; GO:0001540; GO:0050435; GO:0031626; GO:0010815; GO:0009986; GO:0005829; GO:0031597; GO:0008340; GO:0005615; GO:0042447; GO:0043559; GO:1901143; GO:0008286; GO:0004222; GO:0005739; GO:0019048; GO:0045861; GO:0005634; GO:0005782; GO:0005777; GO:0005886; GO:0032461; GO:0051291; GO:0051260; GO:0051289; GO:0051603; GO:0010992; GO:0008270,ATP binding; ATPase activity; beta-amyloid binding; beta-amyloid metabolic process; beta-endorphin binding; bradykinin catabolic process; cell surface; cytosol; cytosolic proteasome complex; determination of adult lifespan; extracellular space; hormone catabolic process; insulin binding; insulin catabolic process; insulin receptor signaling pathway; metalloendopeptidase activity; mitochondrion; modulation by virus of host morphology or physiology; negative regulation of proteolysis; nucleus; peroxisomal matrix; peroxisome; plasma membrane; positive regulation of protein oligomerization; protein heterooligomerization; protein homooligomerization; protein homotetramerization; proteolysis involved in cellular protein catabolic process; ubiquitin homeostasis; zinc ion binding,PF00675;PF05193;PF16187;,,,,,,,,,IDE_HUMAN,Homo sapiens (Human),beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; hormone catabolic process [GO:0042447]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; insulin receptor signaling pathway [GO:0008286]; negative regulation of proteolysis [GO:0045861]; positive regulation of protein oligomerization [GO:0032461]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992] comp79340_c0_seq1,485,41.8557,0.42690012,0,1,,4.00E-13,Q62255,Sal-like protein 3 (MSal) (Spalt-like protein 3),Sal-like protein 3 (MSal) (Spalt-like protein 3),GO:0003677; GO:0035136; GO:0035137; GO:0046872; GO:0045879; GO:0005634; GO:0021891; GO:0006355; GO:0006351,"DNA binding; forelimb morphogenesis; hindlimb morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; nucleus; olfactory bulb interneuron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,SALL3_MOUSE,Mus musculus (Mouse),"forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp79342_c0_seq1,211,51.6588,0.76078264,0,33,,3.00E-08,Q5QNQ9,Collagen alpha-1(XXVII) chain,Collagen alpha-1(XXVII) chain,GO:0005201; GO:0005583; GO:0046872,extracellular matrix structural constituent; fibrillar collagen; metal ion binding,PF01410;PF01391;,,,,,,,,,CORA1_MOUSE,Mus musculus (Mouse),extracellular matrix organization [GO:0030198]; growth plate cartilage chondrocyte development [GO:0003431] comp79346_c0_seq1,247,45.3441,0.63448434,6,6,,3.00E-27,Q9XYM0,Adapter molecule Crk,Adapter molecule Crk,GO:0005070; GO:0007298; GO:0048013; GO:0046529; GO:0007520; GO:0046330; GO:0032319; GO:0032956,"SH3/SH2 adaptor activity; border follicle cell migration; ephrin receptor signaling pathway; imaginal disc fusion, thorax closure; myoblast fusion; positive regulation of JNK cascade; regulation of Rho GTPase activity; regulation of actin cytoskeleton organization",PF00017;PF00018;PF07653;,,,,,,,,,CRK_DROME,Drosophila melanogaster (Fruit fly),"border follicle cell migration [GO:0007298]; ephrin receptor signaling pathway [GO:0048013]; imaginal disc fusion, thorax closure [GO:0046529]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of JNK cascade [GO:0046330]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]" comp79346_c1_seq1,291,42.9553,0.4569694,6,13,,1.00E-08,P42685,Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5),Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5),GO:0005524; GO:0030154; GO:0005737; GO:0008285; GO:0004715; GO:0005634; GO:0005886,ATP binding; cell differentiation; cytoplasm; negative regulation of cell proliferation; non-membrane spanning protein tyrosine kinase activity; nucleus; plasma membrane,PF07714;PF00017;PF00018;,,,,,,,,,FRK_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; innate immune response [GO:0045087]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp79352_c0_seq1,359,40.1114,1.04348636,15,0,,6.00E-08,Q9Z339,Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R),GO:0019853; GO:0030424; GO:0005604; GO:0044297; GO:0071243; GO:0005829; GO:0045174; GO:0004364; GO:0050610; GO:0043209; GO:0031965; GO:0042178,L-ascorbic acid biosynthetic process; axon; basement membrane; cell body; cellular response to arsenic-containing substance; cytosol; glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; methylarsonate reductase activity; myelin sheath; nuclear membrane; xenobiotic catabolic process,PF00043;PF13417;,,,,,,,,,GSTO1_RAT,Rattus norvegicus (Rat),cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; xenobiotic catabolic process [GO:0042178] comp79353_c0_seq1,400,38.25,0.54875471,10,19,,4.00E-37,Q9BU79,Transmembrane protein 243,Transmembrane protein 243,GO:0016021,integral to membrane,PF10856;,,,9.00E-48,ruditapes_c27723,,,,,CG023_HUMAN,Homo sapiens (Human), comp79356_c0_seq1,310,46.7742,0.24174367,9,0,,4.00E-10,P53355,Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1),GO:0005524; GO:0015629; GO:0097190; GO:0005516; GO:0004683; GO:0071346; GO:0005737; GO:0007243; GO:0043066; GO:0017148; GO:0043065; GO:0046777; GO:2000310; GO:0010506,ATP binding; actin cytoskeleton; apoptotic signaling pathway; calmodulin binding; calmodulin-dependent protein kinase activity; cellular response to interferon-gamma; cytoplasm; intracellular protein kinase cascade; negative regulation of apoptotic process; negative regulation of translation; positive regulation of apoptotic process; protein autophosphorylation; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of autophagy,PF12796;PF00531;PF00069;,,,,,,,,,DAPK1_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310] comp79369_c0_seq1,270,37.4074,1.33280517,11,0,,6.00E-07,Q96K80,Zinc finger CCCH domain-containing protein 10,Zinc finger CCCH domain-containing protein 10,GO:0046872,metal ion binding,PF00642;,5.00E-13,CHOYP_ZC3HA.1.1,,,,,,,ZC3HA_HUMAN,Homo sapiens (Human), comp79378_c0_seq1,1457,37.4056,0.45203839,181,0,,6.00E-52,Q708W2,Forkhead box protein J1-A (FoxJ1-A) (FoxJ1a) (xFoxJ1) (Forkhead protein 5) (xFKH5),Forkhead box protein J1-A (FoxJ1-A) (FoxJ1a) (xFoxJ1) (Forkhead protein 5) (xFKH5),GO:0003677; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"DNA binding; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00250;,3.00E-81,CHOYP_FOXJ1.1.1,,,,,,,FXJ1A_XENLA,Xenopus laevis (African clawed frog),"cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp79426_c0_seq1,362,47.7901,0.39190582,14,24,,2.00E-20,Q9P2K2,Thioredoxin domain-containing protein 16,Thioredoxin domain-containing protein 16,GO:0045454; GO:0005576,cell redox homeostasis; extracellular region,PF00085;,,,,,,,,,TXD16_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454] comp79474_c0_seq1,320,41.5625,0.44276294,10,0,,1.00E-55,Q5ZL98,DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A),DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A),GO:0003677; GO:0003899; GO:0005634; GO:0032549; GO:0006351; GO:0008270,"DNA binding; DNA-directed RNA polymerase activity; nucleus; ribonucleoside binding; transcription, DNA-dependent; zinc ion binding",PF04997;PF00623;PF04983;PF05000;PF04998;,4.00E-72,CHOYP_RPC1.1.1,,,,,,,RPC1_CHICK,Gallus gallus (Chicken),transcription from RNA polymerase III promoter [GO:0006383] comp79480_c0_seq1,1270,42.9134,0.38133837,25,9,,1.00E-98,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp79562_c0_seq1,283,41.6961,0.32719303,1,0,,2.00E-07,Q8NFP4,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,2.00E-12,CHOYP_NEMVEDRAFT_V1G239043.2.6,,,,,,,MDGA1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp79568_c1_seq1,328,44.2073,0.38211737,5,18,,3.00E-43,Q9Z0S8,Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Non-erythroid band 3-like protein) (Solute carrier family 4 member 2),Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Non-erythroid band 3-like protein) (Solute carrier family 4 member 2),GO:0005452; GO:0016021,inorganic anion exchanger activity; integral to membrane,PF07565;PF00955;,1.00E-22,CHOYP_B3A2.2.2,,,,,,,B3A2_CAVPO,Cavia porcellus (Guinea pig), comp7956_c0_seq1,517,40.8124,0.46666841,12,2,,3.00E-42,Q1LZA0,GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B),GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B),GO:0006506; GO:0005789; GO:0016021; GO:0016757,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring glycosyl groups",PF03901;,7.00E-34,CHOYP_PIGB.1.1,,,,,,,PIGB_BOVIN,Bos taurus (Bovine),GPI anchor biosynthetic process [GO:0006506] comp79591_c1_seq1,498,38.755,0.38258643,30,52,,7.00E-51,Q12996,Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77),Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77),GO:0003723; GO:0006379; GO:0006378; GO:0000398; GO:0005654; GO:0006369,"RNA binding; mRNA cleavage; mRNA polyadenylation; mRNA splicing, via spliceosome; nucleoplasm; termination of RNA polymerase II transcription",PF05843;,5.00E-61,CHOYP_CSTF3.1.1,,,,,,,CSTF3_HUMAN,Homo sapiens (Human),"mRNA 3'-end processing [GO:0031124]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; termination of RNA polymerase II transcription [GO:0006369]" comp79599_c0_seq1,424,36.3208,0.22898834,8,0,,1.00E-05,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp79660_c0_seq1,400,36.5,0.77713664,9,8,,6.00E-09,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp79683_c0_seq1,294,50.3401,0.88523155,0,34,,2.00E-22,Q5U405,Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease),Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease),GO:0016021; GO:0006508; GO:0005044; GO:0004252,integral to membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF15494;PF00089;,,,7.00E-35,ruditapes_c19446,,,,,TMPSD_MOUSE,Mus musculus (Mouse),establishment of skin barrier [GO:0061436] comp79699_c0_seq1,506,37.5494,1.04464694,24,0,,6.00E-19,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp79757_c0_seq1,378,42.328,0.89177095,4,21,,3.00E-14,Q6V595,Kelch-like protein 6,Kelch-like protein 6,GO:0050853; GO:0002467,B cell receptor signaling pathway; germinal center formation,PF07707;PF00651;PF01344;,,,,,,,,,KLHL6_MOUSE,Mus musculus (Mouse),B cell receptor signaling pathway [GO:0050853]; germinal center formation [GO:0002467] comp79776_c0_seq1,246,36.5854,0.73186395,4,1,,2.00E-10,Q8BGN3,Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) (GPC-Cpde),Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) (GPC-Cpde),GO:0031225; GO:0019695; GO:0005576; GO:0047390; GO:0008889; GO:0016042; GO:0006629; GO:0005886,anchored to membrane; choline metabolic process; extracellular region; glycerophosphocholine cholinephosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; lipid catabolic process; lipid metabolic process; plasma membrane,PF01663;,,,,,,,,,ENPP6_MOUSE,Mus musculus (Mouse),choline metabolic process [GO:0019695]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629] comp79778_c0_seq1,326,62.8834,0.84295856,0,15,,8.00E-26,P81989,Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase),Purine nucleoside phosphorylase (PNP) (Pu-NPase) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase),GO:0009116; GO:0004731,nucleoside metabolic process; purine-nucleoside phosphorylase activity,PF01048;,,,,,,,,,PUNA_CELSP,Cellulomonas sp.,nucleoside metabolic process [GO:0009116] comp79802_c0_seq1,679,45.8027,0.51428683,30,21,,,,,,,,,9.00E-28,CHOYP_LOC100558121.1.1,,,,,,,,, comp79819_c0_seq1,262,32.4427,1.22612509,3,13,,,,,,,,,,,5.00E-11,ruditapes_c3364,,,,,,, comp79846_c0_seq1,358,29.3296,1.18526237,14,5,,9.00E-09,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,,,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp79876_c1_seq1,375,42.1333,0.30435703,5,9,,8.00E-23,Q01974,"Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)","Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)",GO:0005524; GO:0007254; GO:0007223; GO:0060071; GO:0001502; GO:0030154; GO:0030538; GO:0042472; GO:0005887; GO:0007275; GO:0090090; GO:0008285; GO:0090263; GO:0030335; GO:0045893; GO:0001756; GO:0004714; GO:0007169,"ATP binding; JNK cascade; Wnt receptor signaling pathway, calcium modulating pathway; Wnt receptor signaling pathway, planar cell polarity pathway; cartilage condensation; cell differentiation; embryonic genitalia morphogenesis; inner ear morphogenesis; integral to plasma membrane; multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cell proliferation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell migration; positive regulation of transcription, DNA-dependent; somitogenesis; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway",PF01392;PF07679;PF00051;PF07714;,,,,,,,,,ROR2_HUMAN,Homo sapiens (Human),"BMP signaling pathway [GO:0030509]; cartilage condensation [GO:0001502]; cell fate commitment [GO:0045165]; embryonic digit morphogenesis [GO:0042733]; embryonic genitalia morphogenesis [GO:0030538]; inner ear morphogenesis [GO:0042472]; JNK cascade [GO:0007254]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; somitogenesis [GO:0001756]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp79884_c0_seq1,721,43.2732,0.56406359,59,0,,3.00E-68,O60308,Centrosomal protein of 104 kDa (Cep104),Centrosomal protein of 104 kDa (Cep104),GO:0005814,centriole,,2.00E-93,CHOYP_LOC100369449.1.1,,,,,,,CE104_HUMAN,Homo sapiens (Human), comp79896_c1_seq1,291,64.6048,1.09252991,0,14,,3.00E-23,A9LZ77,Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase (Urogen III methylase) (EC 2.1.1.107) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)],Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase (Urogen III methylase) (EC 2.1.1.107) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)],GO:0051287; GO:0009236; GO:0043115; GO:0019354; GO:0051266; GO:0004851,NAD binding; cobalamin biosynthetic process; precorrin-2 dehydrogenase activity; siroheme biosynthetic process; sirohydrochlorin ferrochelatase activity; uroporphyrin-III C-methyltransferase activity,PF10414;PF13241;PF14824;PF00590;,,,,,,,,,CYSG_NEIM0,Neisseria meningitidis serogroup C (strain 053442),cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354] comp79903_c0_seq1,298,62.0805,1.2939327,0,30,,1.00E-18,P0A4M0,DNA gyrase subunit B (EC 5.99.1.3),DNA gyrase subunit B (EC 5.99.1.3),GO:0005524; GO:0003677; GO:0003918; GO:0006265; GO:0006261; GO:0005694; GO:0005737; GO:0000287,ATP binding; DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; DNA topological change; DNA-dependent DNA replication; chromosome; cytoplasm; magnesium ion binding,PF00204;PF00986;PF02518;PF01751;,,,,,,,,,GYRB_STRR6,Streptococcus pneumoniae (strain ATCC BAA-255 / R6),chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268] comp7_c0_seq1,210,33.3333,1.38818937,7,0,,,,,,,,,,,4.00E-11,ruditapes_c4664,,,,,,, comp80029_c0_seq1,370,65.9459,0.99812405,1,8,,1.00E-40,A8LY38,"Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12); GTP cyclohydrolase-2 (EC 3.5.4.25) (GTP cyclohydrolase II)]","Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12); GTP cyclohydrolase-2 (EC 3.5.4.25) (GTP cyclohydrolase II)]",GO:0008686; GO:0005525; GO:0003935; GO:0000287; GO:0030145; GO:0009231; GO:0008270,"3,4-dihydroxy-2-butanone-4-phosphate synthase activity; GTP binding; GTP cyclohydrolase II activity; magnesium ion binding; manganese ion binding; riboflavin biosynthetic process; zinc ion binding",PF00926;PF00925;,,,,,,,,,RIBBA_SALAI,Salinispora arenicola (strain CNS-205),riboflavin biosynthetic process [GO:0009231] comp80040_c0_seq1,220,41.8182,0.11077923,2,38,,4.00E-06,C3YWU0,Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase),GO:0004560; GO:0005576; GO:0006004,alpha-L-fucosidase activity; extracellular region; fucose metabolic process,PF01120;PF16757;,,,,,,,,,FUCO_BRAFL,Branchiostoma floridae (Florida lancelet) (Amphioxus),fucose metabolic process [GO:0006004] comp80054_c0_seq1,288,68.0556,0.90511583,0,11,,8.00E-12,Q146E7,Taurine import ATP-binding protein TauB 1 (EC 3.6.3.36),Taurine import ATP-binding protein TauB 1 (EC 3.6.3.36),GO:0005524; GO:0006200; GO:0005886; GO:0015734; GO:0015411,ATP binding; ATP catabolic process; plasma membrane; taurine transport; taurine-transporting ATPase activity,PF00005;,,,,,,,,,TAUB1_BURXL,Burkholderia xenovorans (strain LB400),taurine transport [GO:0015734] comp80065_c0_seq1,516,45.7364,0.37140944,34,6,,2.00E-13,O60462,Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2),Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2),GO:0001525; GO:0030424; GO:0048846; GO:0007155; GO:0019955; GO:0005576; GO:0019838; GO:0007507; GO:0008201; GO:0016021; GO:0046872; GO:0050919; GO:0021675; GO:0001755; GO:0005886; GO:0010595; GO:0001938; GO:0017154; GO:0002116; GO:1902285; GO:0061549; GO:0097490; GO:0097491; GO:0048010; GO:0005021,angiogenesis; axon; axon extension involved in axon guidance; cell adhesion; cytokine binding; extracellular region; growth factor binding; heart development; heparin binding; integral to membrane; metal ion binding; negative chemotaxis; nerve development; neural crest cell migration; plasma membrane; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; semaphorin receptor activity; semaphorin receptor complex; semaphorin-plexin signaling pathway involved in neuron projection guidance; sympathetic ganglion development; sympathetic neuron projection extension; sympathetic neuron projection guidance; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor-activated receptor activity,PF00431;PF11980;PF00754;PF00629;,,,,,,,,,NRP2_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; nerve development [GO:0021675]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp80100_c0_seq1,466,42.2747,0.39618422,21,5,,,,,,,,,,,6.00E-19,ruditapes_c22175,,,,,,, comp80104_c2_seq1,265,45.6604,0.58238377,16,0,,1.00E-06,P24043,Laminin subunit alpha-2 (Laminin M chain) (Laminin-12 subunit alpha) (Laminin-2 subunit alpha) (Laminin-4 subunit alpha) (Merosin heavy chain),Laminin subunit alpha-2 (Laminin M chain) (Laminin-12 subunit alpha) (Laminin-2 subunit alpha) (Laminin-4 subunit alpha) (Merosin heavy chain),GO:0007411; GO:0005604; GO:0007155; GO:0030198; GO:0005606; GO:0007517; GO:0032224; GO:0030155; GO:0030334; GO:0045995; GO:0042383; GO:0005198,"axon guidance; basement membrane; cell adhesion; extracellular matrix organization; laminin-1 complex; muscle organ development; positive regulation of synaptic transmission, cholinergic; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; sarcolemma; structural molecule activity",PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;,,,,,,,,,LAMA2_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; muscle organ development [GO:0007517]; myelination in peripheral nervous system [GO:0022011]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]" comp80127_c0_seq1,455,37.3626,0.44180144,14,17,,,,,,,,,6.00E-21,CHOYP_WU_FC28F08.1.1,,,,,,,,, comp80136_c0_seq1,232,65.9483,1.08842853,0,8,,1.00E-08,P0C0L7,Proline/betaine transporter (Proline porter II) (PPII),Proline/betaine transporter (Proline porter II) (PPII),GO:0015653; GO:0005297; GO:0042538; GO:0005887,glycine betaine:hydrogen symporter activity; hydrogen:proline symporter activity; hyperosmotic salinity response; integral to plasma membrane,PF08946;PF00083;,,,,,,,,,PROP_ECOLI,Escherichia coli (strain K12),amino acid transport [GO:0006865] comp80147_c0_seq1,416,35.0962,0.54786353,10,23,,7.00E-07,Q8C525,Protein MB21D2 (Mab-21 domain-containing protein 2),Protein MB21D2 (Mab-21 domain-containing protein 2),,,PF03281;,,,,,,,,,M21D2_MOUSE,Mus musculus (Mouse), comp80150_c0_seq1,648,38.7346,0.66233096,1,0,,1.00E-36,P00789,Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase) (CANP) (Calpain-1 large subunit) (Mu/M-type),Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase) (CANP) (Calpain-1 large subunit) (Mu/M-type),GO:0005509; GO:0004198; GO:0005737; GO:0005886; GO:0006508; GO:0032801,calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; plasma membrane; proteolysis; receptor catabolic process,PF01067;PF00648;,,,,,,,,,CANX_CHICK,Gallus gallus (Chicken),proteolysis [GO:0006508] comp80150_c0_seq2,630,38.254,0.65375217,5,0,,1.00E-33,P13135,Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit),Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit),GO:0005509; GO:0004198; GO:0005737; GO:0005886,calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; plasma membrane,PF13833;,,,,,,,,,CPNS1_BOVIN,Bos taurus (Bovine),proteolysis [GO:0006508] comp80157_c0_seq2,627,37.6396,0.19117248,12,3,,,,,,,,,,,1.00E-16,ruditapes_c18492,,,,,,, comp80167_c0_seq1,302,48.3444,0.28868457,13,6,,9.00E-40,Q5RIW8,Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23),Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11573;,1.00E-34,CHOYP_MED23.1.1,,,,,,,MED23_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"cardiovascular system development [GO:0072358]; negative regulation of neurogenesis [GO:0050768]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp80168_c0_seq1,474,41.5612,0.72677919,2,15,,7.00E-49,Q6PFP6,NADPH-dependent diflavin oxidoreductase 1 (EC 1.6.-.-) (NADPH-dependent FMN and FAD-containing oxidoreductase),NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase),GO:0010181; GO:0003958; GO:0008219; GO:0036245; GO:0005829; GO:0005506; GO:0016709; GO:0048471,"FMN binding; NADPH-hemoprotein reductase activity; cell death; cellular response to menadione; cytosol; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; perinuclear region of cytoplasm",PF00667;PF00258;PF00175;,7.00E-21,CHOYP_BRAFLDRAFT_122922.1.1,,,,,,,NDOR1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226] comp80168_c0_seq2,392,43.3673,0.74432303,0,4,,2.00E-11,P29474,"Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII)","Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII)",GO:0010181; GO:0000139; GO:0050661; GO:0003958; GO:0001525; GO:0034618; GO:0006527; GO:0007596; GO:0001974; GO:0046870; GO:0005901; GO:0005856; GO:0005829; GO:0030666; GO:0043542; GO:0050660; GO:0020037; GO:0001701; GO:0051701; GO:0005506; GO:0031663; GO:0030324; GO:0007005; GO:0045776; GO:0051926; GO:0008285; GO:1902042; GO:0051346; GO:0014740; GO:0010544; GO:0043267; GO:0006809; GO:0007263; GO:0004517; GO:0005634; GO:0001542; GO:0090382; GO:0045766; GO:0031284; GO:0045909; GO:0050880; GO:0050999; GO:0002028; GO:0003100; GO:0003057; GO:0034405; GO:0009408; GO:0014806; GO:0034617,FMN binding; Golgi membrane; NADP binding; NADPH-hemoprotein reductase activity; angiogenesis; arginine binding; arginine catabolic process; blood coagulation; blood vessel remodeling; cadmium ion binding; caveola; cytoskeleton; cytosol; endocytic vesicle membrane; endothelial cell migration; flavin adenine dinucleotide binding; heme binding; in utero embryonic development; interaction with host; iron ion binding; lipopolysaccharide-mediated signaling pathway; lung development; mitochondrion organization; negative regulation of blood pressure; negative regulation of calcium ion transport; negative regulation of cell proliferation; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of hydrolase activity; negative regulation of muscle hyperplasia; negative regulation of platelet activation; negative regulation of potassium ion transport; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; nitric-oxide synthase activity; nucleus; ovulation from ovarian follicle; phagosome maturation; positive regulation of angiogenesis; positive regulation of guanylate cyclase activity; positive regulation of vasodilation; regulation of blood vessel size; regulation of nitric-oxide synthase activity; regulation of sodium ion transport; regulation of systemic arterial blood pressure by endothelin; regulation of the force of heart contraction by chemical signal; response to fluid shear stress; response to heat; smooth muscle hyperplasia; tetrahydrobiopterin binding,PF00667;PF00258;PF00175;PF02898;,,,,,,,,,NOS3_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; arginine catabolic process [GO:0006527]; blood vessel remodeling [GO:0001974]; cell redox homeostasis [GO:0045454]; endothelial cell migration [GO:0043542]; in utero embryonic development [GO:0001701]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of muscle hyperplasia [GO:0014740]; negative regulation of platelet activation [GO:0010544]; negative regulation of potassium ion transport [GO:0043267]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; ovulation from ovarian follicle [GO:0001542]; positive regulation of angiogenesis [GO:0045766]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of vasodilation [GO:0045909]; regulation of blood pressure [GO:0008217]; regulation of blood vessel size [GO:0050880]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of sodium ion transport [GO:0002028]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of the force of heart contraction by chemical signal [GO:0003057]; removal of superoxide radicals [GO:0019430]; response to fluid shear stress [GO:0034405]; response to heat [GO:0009408]; smooth muscle hyperplasia [GO:0014806] comp80172_c0_seq1,515,44.2718,0.59722447,18,19,,6.00E-27,Q9Y6K1,DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA),DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA),GO:0003886; GO:0051718; GO:0003677; GO:0043045; GO:0043046; GO:0010424; GO:0046498; GO:0046499; GO:0071230; GO:0003682; GO:0000775; GO:0005737; GO:0000791; GO:0044027; GO:0046872; GO:0006346; GO:0000122; GO:0005720; GO:0016363; GO:0006349; GO:0007283; GO:0045322,"DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; DNA binding; DNA methylation involved in embryo development; DNA methylation involved in gamete generation; DNA methylation on cytosine within a CG sequence; S-adenosylhomocysteine metabolic process; S-adenosylmethioninamine metabolic process; cellular response to amino acid stimulus; chromatin binding; chromosome, centromeric region; cytoplasm; euchromatin; hypermethylation of CpG island; metal ion binding; methylation-dependent chromatin silencing; negative regulation of transcription from RNA polymerase II promoter; nuclear heterochromatin; nuclear matrix; regulation of gene expression by genetic imprinting; spermatogenesis; unmethylated CpG binding",PF00145;PF00855;,,,,,,,,,DNM3A_HUMAN,Homo sapiens (Human),"aging [GO:0007568]; cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; DNA methylation on cytosine within a CG sequence [GO:0010424]; hepatocyte apoptotic process [GO:0097284]; hypermethylation of CpG island [GO:0044027]; methylation-dependent chromatin silencing [GO:0006346]; mitotic cell cycle [GO:0000278]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; regulation of gene expression by genetic imprinting [GO:0006349]; response to antidepressant [GO:0036276]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; spermatogenesis [GO:0007283]" comp80198_c1_seq1,252,36.5079,0.83855487,7,0,,1.00E-07,A1YFW2,Zinc finger and SCAN domain-containing protein 12 (Zinc finger protein 96),Zinc finger and SCAN domain-containing protein 12 (Zinc finger protein 96),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;PF13912;,,,,,,,,,ZSC12_PANPA,Pan paniscus (Pygmy chimpanzee) (Bonobo),"transcription, DNA-templated [GO:0006351]" comp80198_c1_seq2,207,37.6812,0.96298544,0,0,,3.00E-12,Q5EXX3,Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon),GO:0003677; GO:0046872; GO:0005634; GO:0045944; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF13912;,,,,,,,,,ZBT38_RAT,Rattus norvegicus (Rat),"cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]" comp80217_c0_seq1,354,42.3729,0.44977734,5,43,,1.00E-17,Q4J9D2,Uncharacterized protein Saci_1252,Uncharacterized protein Saci_1252,,,PF01661;,,,,,,,,,Y1252_SULAC,Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770), comp80221_c1_seq1,426,41.0798,1.10924866,7,18,,1.00E-28,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp80295_c1_seq1,294,41.4966,1.11743717,9,5,,3.00E-06,P61315,"Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)","Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)",GO:0032580; GO:0009058; GO:0001733; GO:0016021,Golgi cisterna membrane; biosynthetic process; galactosylceramide sulfotransferase activity; integral to membrane,PF06990;,,,,,,,,,G3ST3_MOUSE,Mus musculus (Mouse),glycolipid biosynthetic process [GO:0009247] comp80321_c0_seq1,238,35.2941,0.13556677,6,4,,,,,,,,,5.00E-19,CHOYP_BRAFLDRAFT_132233.4.4,3.00E-26,ruditapes_c23115,,,,,,, comp80374_c1_seq1,250,68,1.39137481,0,10,,1.00E-21,B7GH22,3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase),3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase),GO:0003861; GO:0009316; GO:0009098,3-isopropylmalate dehydratase activity; 3-isopropylmalate dehydratase complex; leucine biosynthetic process,PF00694;,,,,,,,,,LEUD_ANOFW,Anoxybacillus flavithermus (strain DSM 21510 / WK1),leucine biosynthetic process [GO:0009098] comp80375_c0_seq1,287,43.2056,0.303561,5,9,,8.00E-13,Q9HA65,TBC1 domain family member 17,TBC1 domain family member 17,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF12068;PF00566;,4.00E-14,CHOYP_TBC15.1.1,,,,,,,TBC17_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" comp8039_c0_seq1,208,37.9808,0.53659777,0,7,,5.00E-10,Q8TBB6,Probable cationic amino acid transporter (Solute carrier family 7 member 14),Probable cationic amino acid transporter (Solute carrier family 7 member 14),GO:0015171; GO:0016021; GO:0010923,amino acid transmembrane transporter activity; integral to membrane; negative regulation of phosphatase activity,PF13520;PF13906;,,,,,,,,,S7A14_HUMAN,Homo sapiens (Human),negative regulation of phosphatase activity [GO:0010923] comp80412_c0_seq1,299,35.1171,0.33161756,5,13,,,,,,,,,,,1.00E-13,ruditapes_c15855,,,,,,, comp8047_c0_seq1,286,44.0559,0.80270496,2,0,,3.00E-13,Q3SWX0,Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog),Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog),GO:0005769; GO:0016021; GO:0015095; GO:0005886,early endosome; integral to membrane; magnesium ion transmembrane transporter activity; plasma membrane,PF05653;,2.00E-18,CHOYP_NIPA2.1.1,,,,,,,NIPA2_BOVIN,Bos taurus (Bovine),magnesium ion transport [GO:0015693] comp80493_c0_seq1,212,41.9811,0.75763881,3,0,,5.00E-06,Q6V1P9,Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ),Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;,,,,,,,,,PCD23_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp80509_c0_seq1,397,45.8438,0.62669971,16,3,,2.00E-08,Q9QYE3,B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9),B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9),GO:0030183; GO:0030217; GO:0005737; GO:0046872; GO:0010629; GO:0016604; GO:0003676; GO:0016925; GO:0006355; GO:0003714; GO:0006351,"B cell differentiation; T cell differentiation; cytoplasm; metal ion binding; negative regulation of gene expression; nuclear body; nucleic acid binding; protein sumoylation; regulation of transcription, DNA-dependent; transcription corepressor activity; transcription, DNA-dependent",,,,,,,,,,BC11A_MOUSE,Mus musculus (Mouse),B cell differentiation [GO:0030183]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of neuron projection development [GO:0010976]; protein sumoylation [GO:0016925]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366] comp80516_c0_seq1,233,60.0858,0.9553146,0,16,,6.00E-09,Q6D3B1,Glutathione transport system permease protein GsiC,Glutathione transport system permease protein GsiC,GO:0016021; GO:0005886; GO:0005215,integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,GSIC_ERWCT,Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica),transport [GO:0006810] comp80519_c0_seq1,294,34.6939,0.23256083,14,11,,4.00E-27,Q5FVI3,Leucine-rich repeat-containing protein 57,Leucine-rich repeat-containing protein 57,,,PF00560;PF13855;,,,,,,,,,LRC57_RAT,Rattus norvegicus (Rat), comp80562_c0_seq2,466,45.279,0.75661915,3,0,,4.00E-54,Q9JJ22,Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP),Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP),GO:0004177; GO:0019882; GO:0005788; GO:0005789; GO:0005576; GO:0016021; GO:0005138; GO:0006509; GO:0008235; GO:0008270,aminopeptidase activity; antigen processing and presentation; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular region; integral to membrane; interleukin-6 receptor binding; membrane protein ectodomain proteolysis; metalloexopeptidase activity; zinc ion binding,PF11838;PF01433;,5.00E-16,CHOYP_PHUM_PHUM512710.1.2,,,,,,,ERAP1_RAT,Rattus norvegicus (Rat),adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217] comp80583_c0_seq1,492,43.0894,0.13163102,15,10,,9.00E-09,Q7Z7G8,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp80634_c0_seq1,576,44.4444,0.49412921,26,13,,2.00E-51,Q9JLB4,Cubilin (Intrinsic factor-cobalamin receptor),Cubilin (Intrinsic factor-cobalamin receptor),GO:0005794; GO:0016324; GO:0005903; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0030139; GO:0005783; GO:0005768; GO:0010008; GO:0042953; GO:0005765; GO:0004872; GO:0006898,Golgi apparatus; apical plasma membrane; brush border; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; endocytic vesicle; endoplasmic reticulum; endosome; endosome membrane; lipoprotein transport; lysosomal membrane; receptor activity; receptor-mediated endocytosis,PF00431;PF00008;PF12947;PF07645;,1.00E-24,CHOYP_LOC591417.2.2,,,,,,,CUBN_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898] comp80677_c0_seq1,354,44.0678,0.24365328,6,8,,4.00E-33,Q99758,ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3),GO:0005524; GO:0042626; GO:0097208; GO:0097233; GO:0016021; GO:0005886; GO:0042493,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; alveolar lamellar body; alveolar lamellar body membrane; integral to membrane; plasma membrane; response to drug",PF00005;,,,,,,,,,ABCA3_HUMAN,Homo sapiens (Human),cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp80686_c0_seq1,728,38.3242,0.30173898,13,83,,2.00E-27,Q9BS31,Zinc finger protein 649,Zinc finger protein 649,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN649_HUMAN,Homo sapiens (Human),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp80695_c0_seq1,409,42.7873,0.6980136,10,8,,6.00E-27,P47736,Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1),Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1),GO:0005096; GO:0003924; GO:0000139; GO:0005829; GO:0016020; GO:0032318; GO:0007165,GTPase activator activity; GTPase activity; Golgi membrane; cytosol; membrane; regulation of Ras GTPase activity; signal transduction,PF02188;PF02145;,2.00E-19,CHOYP_LOC100889245.2.2,,,,,,,RPGP1_HUMAN,Homo sapiens (Human),cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp80710_c0_seq1,471,44.586,0.51754619,0,0,,3.00E-22,Q6ZN16,Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15),Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15),GO:0005524; GO:0004709; GO:0000165; GO:0000186; GO:0046872,ATP binding; MAP kinase kinase kinase activity; MAPK cascade; activation of MAPKK activity; metal ion binding,PF13281;PF00069;,1.00E-16,CHOYP_ASK1.2.2,,,,,,,M3K15_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186] comp80710_c0_seq2,618,42.8803,0.46247248,5,3,,1.00E-21,Q99683,Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5),GO:0005524; GO:0004709; GO:0007257; GO:0070301; GO:0008656; GO:0005783; GO:0045087; GO:0008631; GO:0000287; GO:0019048; GO:0043065; GO:0042803,ATP binding; MAP kinase kinase kinase activity; activation of JUN kinase activity; cellular response to hydrogen peroxide; cysteine-type endopeptidase activator activity involved in apoptotic process; endoplasmic reticulum; innate immune response; intrinsic apoptotic signaling pathway in response to oxidative stress; magnesium ion binding; modulation by virus of host morphology or physiology; positive regulation of apoptotic process; protein homodimerization activity,PF13281;PF00069;,,,,,,,,,M3K5_HUMAN,Homo sapiens (Human),activation of JUN kinase activity [GO:0007257]; activation of MAPKK activity [GO:0000186]; apoptotic signaling pathway [GO:0097190]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]; viral process [GO:0016032] comp80713_c1_seq1,389,59.6401,1.04410596,0,36,,2.00E-84,Q6AB26,UPF0271 protein PPA0282,UPF0271 protein PPA0282,GO:0005975; GO:0003824,carbohydrate metabolic process; catalytic activity,PF03746;,,,,,,,,,Y282_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),carbohydrate metabolic process [GO:0005975] comp80715_c0_seq1,547,44.6069,0.48413346,17,17,,4.00E-38,Q8NFA0,Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),GO:0005794; GO:0005509; GO:0008234; GO:0016020; GO:0016579; GO:0004221; GO:0006511,Golgi apparatus; calcium ion binding; cysteine-type peptidase activity; membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF06337;PF13202;PF14836;PF00443;,,,,,,,,,UBP32_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp80752_c0_seq1,299,31.1037,0.73892452,3,22,,,,,,,,,,,5.00E-11,ruditapes_c17176,,,,,,, comp80771_c0_seq1,206,59.2233,1.13210215,0,16,,7.00E-20,Q7NWN7,Chaperone protein ClpB,Chaperone protein ClpB,GO:0005524; GO:0005737; GO:0017111; GO:0016485; GO:0009408,ATP binding; cytoplasm; nucleoside-triphosphatase activity; protein processing; response to heat,PF00004;PF07724;PF02861;PF10431;,,,,,,,,,CLPB_CHRVO,Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757),protein processing [GO:0016485]; response to heat [GO:0009408] comp80788_c0_seq1,744,44.6237,0.33135716,19,21,,3.00E-58,Q149N8,"E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)","E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)",GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0016874; GO:0000786; GO:0006334; GO:0005634; GO:0016567; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; ligase activity; nucleosome; nucleosome assembly; nucleus; protein ubiquitination; zinc ion binding,PF00271;PF00538;PF00176;,2.00E-17,CHOYP_SHPRH.1.3,,,,,,,SHPRH_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] comp80808_c0_seq1,563,38.0107,0.61978218,22,5,,3.00E-23,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,5.00E-42,CHOYP_BRAFLDRAFT_106560.14.14,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp80810_c0_seq1,543,44.0147,0.96467911,9,36,,5.00E-38,Q8BYI9,Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin),Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin),GO:0008306; GO:0009986; GO:0005737; GO:0030198; GO:0035641; GO:0060291; GO:0045121; GO:0048692; GO:0022408; GO:0050805; GO:0050885; GO:0007158; GO:0005634; GO:0072534; GO:0051968; GO:0005578; GO:0046625; GO:0050808; GO:0022029,"associative learning; cell surface; cytoplasm; extracellular matrix organization; locomotory exploration behavior; long-term synaptic potentiation; membrane raft; negative regulation of axon extension involved in regeneration; negative regulation of cell-cell adhesion; negative regulation of synaptic transmission; neuromuscular process controlling balance; neuron cell-cell adhesion; nucleus; perineuronal net; positive regulation of synaptic transmission, glutamatergic; proteinaceous extracellular matrix; sphingolipid binding; synapse organization; telencephalon cell migration",PF00147;PF00041;,,,,,,,,,TENR_MOUSE,Mus musculus (Mouse),"associative learning [GO:0008306]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; synapse organization [GO:0050808]; telencephalon cell migration [GO:0022029]" comp80826_c0_seq1,208,69.2308,1.22106036,0,7,,3.00E-41,A1W8S8,Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21),Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21),GO:0009435; GO:0005737; GO:0016874; GO:0019357; GO:0004516; GO:0004514,NAD biosynthetic process; cytoplasm; ligase activity; nicotinate nucleotide biosynthetic process; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity,PF04095;,,,,,,,,,PNCB_ACISJ,Acidovorax sp. (strain JS42),NAD biosynthetic process [GO:0009435]; nicotinate nucleotide biosynthetic process [GO:0019357] comp80835_c0_seq1,531,44.6328,0.79880163,0,21,,4.00E-61,Q1JPJ2,"Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)","Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)",GO:0010815; GO:0005737; GO:0030145; GO:0070006; GO:0006508,bradykinin catabolic process; cytoplasm; manganese ion binding; metalloaminopeptidase activity; proteolysis,PF01321;PF00557;PF16188;,4.00E-30,CHOYP_TRIADDRAFT_64367.1.1,,,,,,,XPP1_BOVIN,Bos taurus (Bovine),bradykinin catabolic process [GO:0010815] comp80835_c0_seq2,513,44.0546,0.76698634,0,3,,,,,,,,,8.00E-27,CHOYP_XPP1.2.2,,,,,,,,, comp80887_c0_seq1,448,43.9732,0.51383943,5,67,,2.00E-15,O70582,"Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (Epidermis-type lipoxygenase 2) (e-LOX 2)","Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (Epidermis-type lipoxygenase 2) (e-LOX 2)",GO:0004052; GO:0019369; GO:0046513; GO:0005737; GO:0061436; GO:0051122; GO:0005506; GO:1990136; GO:0043651; GO:0019372; GO:0043410; GO:0010628; GO:0070257; GO:0006497,arachidonate 12-lipoxygenase activity; arachidonic acid metabolic process; ceramide biosynthetic process; cytoplasm; establishment of skin barrier; hepoxilin biosynthetic process; iron ion binding; linoleate 9S-lipoxygenase activity; linoleic acid metabolic process; lipoxygenase pathway; positive regulation of MAPK cascade; positive regulation of gene expression; positive regulation of mucus secretion; protein lipidation,PF00305;PF01477;,,,,,,,,,LX12B_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipoxygenase pathway [GO:0019372]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; protein lipidation [GO:0006497]; sphingolipid metabolic process [GO:0006665] comp80887_c1_seq1,293,36.5188,0.6255392,0,41,,3.00E-07,O16025,Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)],GO:0047677; GO:0019369; GO:0004096; GO:0005737; GO:0020037; GO:0047987; GO:0005506; GO:0016020; GO:0031408,arachidonate 8(R)-lipoxygenase activity; arachidonic acid metabolic process; catalase activity; cytoplasm; heme binding; hydroperoxide dehydratase activity; iron ion binding; membrane; oxylipin biosynthetic process,PF00305;PF01477;,,,,,,,,,AOSL_PLEHO,Plexaura homomalla (Black sea rod),arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408] comp80942_c0_seq1,451,42.1286,0.75200015,2,22,,6.00E-65,Q8R3D1,TBC1 domain family member 13,TBC1 domain family member 13,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,1.00E-36,CHOYP_TBC13.1.1,,,,,,,TBC13_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp80957_c0_seq1,235,59.1489,1.24474828,0,16,,7.00E-21,P64326,Transcription-repair-coupling factor (TRCF) (EC 3.6.4.-),,GO:0005524; GO:0008026; GO:0006281; GO:0005829; GO:0003684; GO:0005886,ATP binding; ATP-dependent helicase activity; DNA repair; cytosol; damaged DNA binding; plasma membrane,,,,,,,,,,MFD_MYCTU,, comp80964_c0_seq1,259,43.6293,0.82909399,4,12,,3.00E-13,Q6DDK2,Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0016717; GO:0006636,"endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; unsaturated fatty acid biosynthetic process",PF00173;PF00487;,,,,,,,,,FADS2_XENLA,Xenopus laevis (African clawed frog),unsaturated fatty acid biosynthetic process [GO:0006636] comp81012_c0_seq1,202,50,1.27676085,7,20,,2.00E-35,Q54BE0,Heat shock cognate 70 kDa protein 3 (HSC70-3),Heat shock cognate 70 kDa protein 3 (HSC70-3),GO:0005524,ATP binding,PF00012;,8.00E-28,CHOYP_HSPA8.1.1,,,,,,,HS7C3_DICDI,Dictyostelium discoideum (Slime mold), comp81018_c2_seq1,275,49.0909,0.492424,3,11,,2.00E-32,Q96L93,Kinesin-like protein KIF16B (Sorting nexin-23),Kinesin-like protein KIF16B (Sorting nexin-23),GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,6.00E-31,CHOYP_KI16B.3.3,,,,,,,KI16B_HUMAN,Homo sapiens (Human),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp81078_c0_seq1,229,58.952,0.75725764,0,23,,4.00E-08,Q70LM5,Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)],Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)],GO:0017000; GO:0016853; GO:0016874; GO:0031177,antibiotic biosynthetic process; isomerase activity; ligase activity; phosphopantetheine binding,PF00501;PF13193;PF00668;PF00550;,,,,,,,,,LGRC_BREPA,Brevibacillus parabrevis,antibiotic biosynthetic process [GO:0017000] comp81093_c0_seq1,224,46.875,0.25724598,5,4,,2.00E-13,Q03601,RING finger protein nhl-1,RING finger protein nhl-1,GO:0008270,zinc ion binding,PF01436;PF00097;,,,,,,,,,NHL1_CAEEL,Caenorhabditis elegans,protein ubiquitination [GO:0016567] comp81095_c0_seq1,281,50.1779,0.69345141,6,14,,4.00E-46,Q9NUB1,"Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)","Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)",GO:0016208; GO:0005524; GO:0019413; GO:0003987; GO:0006085; GO:0019427; GO:0006069; GO:0005759; GO:0019542; GO:0006805,AMP binding; ATP binding; acetate biosynthetic process; acetate-CoA ligase activity; acetyl-CoA biosynthetic process; acetyl-CoA biosynthetic process from acetate; ethanol oxidation; mitochondrial matrix; propionate biosynthetic process; xenobiotic metabolic process,PF16177;PF00501;PF13193;,1.00E-34,CHOYP_BRAFLDRAFT_59014.1.1,,,,,,,ACS2L_HUMAN,Homo sapiens (Human),acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; ethanol oxidation [GO:0006069]; propionate biosynthetic process [GO:0019542] comp81127_c0_seq1,316,41.1392,1.07588956,4,48,,,,,,,,,9.00E-11,CHOYP_TVAG_355490.4.22,,,,,,,,, comp81148_c1_seq1,203,50.2463,0.62746621,0,10,,6.00E-26,Q96IG2,F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like),GO:0005737,cytoplasm,PF12937;PF13516;,1.00E-24,CHOYP_ISCW_ISCW014887.1.1,,,,,,,FXL20_HUMAN,Homo sapiens (Human),behavioral fear response [GO:0001662] comp81158_c0_seq1,279,42.2939,0.48485471,0,29,,9.00E-11,Q92928,Putative Ras-related protein Rab-1C (hRab1c),Putative Ras-related protein Rab-1C (hRab1c),GO:0005525; GO:0005737; GO:0016020; GO:0015031; GO:0007264,GTP binding; cytoplasm; membrane; protein transport; small GTPase mediated signal transduction,PF00071;,,,,,,,,,RAB1C_HUMAN,Homo sapiens (Human),ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] comp81194_c0_seq1,310,44.8387,0.64954728,7,9,,7.00E-09,Q7TSH8,Uncharacterized protein KIAA0195,Transmembrane protein 94,GO:0016021,integral to membrane,,,,,,,,,,K0195_MOUSE,Mus musculus (Mouse), comp81261_c0_seq1,575,45.2174,0.61791712,10,27,,4.00E-48,P51871,Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),GO:0070330; GO:0005789; GO:0020037; GO:0006954; GO:0005506; GO:0006691,aromatase activity; endoplasmic reticulum membrane; heme binding; inflammatory response; iron ion binding; leukotriene metabolic process,PF00067;,3.00E-27,CHOYP_BRAFLDRAFT_61250.12.14,,,,,,,CP4F6_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691] comp81263_c0_seq1,694,45.6772,0.28341956,11,59,,5.00E-14,Q792I0,Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3),Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3),GO:0016323; GO:0005911; GO:0006887; GO:0043005; GO:0007269; GO:0014069; GO:0045211; GO:0015031; GO:0045202; GO:0005923,basolateral plasma membrane; cell-cell junction; exocytosis; neuron projection; neurotransmitter secretion; postsynaptic density; postsynaptic membrane; protein transport; synapse; tight junction,PF02828;PF00595;,3.00E-28,CHOYP_LOC100372510.1.1,,,,,,,LIN7C_RAT,Rattus norvegicus (Rat),exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031] comp81269_c0_seq1,767,45.1108,0.84964441,35,5,,1.00E-133,Q9UPW8,Protein unc-13 homolog A (Munc13-1),Protein unc-13 homolog A (Munc13-1),GO:0050435; GO:0030054; GO:0005737; GO:0019992; GO:0060384; GO:0035556; GO:0046872; GO:0031594; GO:0007528; GO:0001956; GO:0042734; GO:0048172; GO:0035249; GO:0016081; GO:0016188; GO:0016082,"beta-amyloid metabolic process; cell junction; cytoplasm; diacylglycerol binding; innervation; intracellular signal transduction; metal ion binding; neuromuscular junction; neuromuscular junction development; positive regulation of neurotransmitter secretion; presynaptic membrane; regulation of short-term neuronal synaptic plasticity; synaptic transmission, glutamatergic; synaptic vesicle docking involved in exocytosis; synaptic vesicle maturation; synaptic vesicle priming",PF00130;PF00168;PF06292;PF10540;,2.00E-130,CHOYP_LOC100650524.2.2,,,,,,,UN13A_HUMAN,Homo sapiens (Human),"beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]" comp81271_c0_seq1,474,35.654,0.4716333,1,33,,1.00E-28,Q9D2G9,HHIP-like protein 2,HHIP-like protein 2,GO:0005975; GO:0005576; GO:0016901; GO:0048038,"carbohydrate metabolic process; extracellular region; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; quinone binding",PF03024;PF07995;,,,,,,,,,HIPL2_MOUSE,Mus musculus (Mouse),carbohydrate metabolic process [GO:0005975] comp81271_c1_seq1,446,41.0314,0.74767401,9,31,,6.00E-06,Q94F08,HIPL2 protein,HIPL2 protein,GO:0046658; GO:0005975; GO:0016901; GO:0048038,"anchored to plasma membrane; carbohydrate metabolic process; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; quinone binding",PF03024;PF07995;,,,,,,,,,HIPL2_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975] comp81274_c0_seq1,421,40.1425,0.43225295,9,25,,1.00E-11,Q8NBP0,Tetratricopeptide repeat protein 13 (TPR repeat protein 13),Tetratricopeptide repeat protein 13 (TPR repeat protein 13),,,PF00515;PF13181;,,,,,,,,,TTC13_HUMAN,Homo sapiens (Human), comp81300_c0_seq1,762,47.6378,0.48835805,3,0,,4.00E-50,Q9Y485,DmX-like protein 1 (X-like 1 protein),DmX-like protein 1 (X-like 1 protein),,,PF12234;PF00400;,,,,,,,,,DMXL1_HUMAN,Homo sapiens (Human), comp81300_c0_seq3,735,47.483,0.48516899,0,0,,,,,,,,,2.00E-80,CHOYP_AGAP_AGAP010490.1.1,,,,,,,,, comp81301_c0_seq2,318,47.1698,0.4700728,5,4,,2.00E-30,Q1RLX4,Trafficking protein particle complex subunit 11 (Protein foie gras),Trafficking protein particle complex subunit 11 (Protein foie gras),GO:0005794; GO:0001889; GO:0060041; GO:0016192,Golgi apparatus; liver development; retina development in camera-type eye; vesicle-mediated transport,PF11817;PF12742;,5.00E-39,CHOYP_BRAFLDRAFT_87429.1.1,,,,,,,TPC11_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),liver development [GO:0001889]; retina development in camera-type eye [GO:0060041]; vesicle-mediated transport [GO:0016192] comp81306_c0_seq1,406,29.3103,0.81447035,8,26,,2.00E-17,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,1.00E-13,ruditapes_c19911,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp81334_c0_seq1,294,45.2381,0.86726467,8,0,,2.00E-22,Q07954,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0034185; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0030666; GO:0005887; GO:0070325; GO:0042954; GO:0005765; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0007603; GO:0010875; GO:0032403; GO:0004872; GO:0006898; GO:0032956; GO:0032429; GO:0001523,"aorta morphogenesis; apolipoprotein binding; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; endocytic vesicle membrane; integral to plasma membrane; lipoprotein particle receptor binding; lipoprotein transporter activity; lysosomal membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; phototransduction, visible light; positive regulation of cholesterol efflux; protein complex binding; receptor activity; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; retinoid metabolic process",PF12662;PF16472;PF07645;PF00057;PF00058;,,,,,,,,,LRP1_HUMAN,Homo sapiens (Human),aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523] comp81337_c0_seq1,318,35.5346,0.60531908,10,25,,3.00E-16,Q6J212,RING finger protein 114 (Zinc finger protein 313),E3 ubiquitin-protein ligase RNF114 (EC 6.3.2.-) (RING finger protein 114) (Zinc finger protein 313),GO:0030154; GO:0007275; GO:0007283; GO:0008270,cell differentiation; multicellular organismal development; spermatogenesis; zinc ion binding,PF05605;PF13445;,,,,,,,,,RN114_PANTR,Pan troglodytes (Chimpanzee),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283] comp81345_c0_seq1,251,39.4422,0.83307107,14,0,,8.00E-12,Q54M77,Probable serine/threonine-protein kinase roco8 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 8),Probable serine/threonine-protein kinase roco8 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 8),GO:0005524; GO:0035556; GO:0004674,ATP binding; intracellular signal transduction; protein serine/threonine kinase activity,PF16095;PF00610;PF13855;PF07714;PF08477;,,,,,,,,,ROCO8_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp81351_c0_seq1,334,30.2395,0.13432358,5,0,,,,,,,,,,,4.00E-13,ruditapes_c27413,,,,,,, comp81362_c0_seq1,410,49.5122,0.39895403,6,11,,1.00E-45,Q91XQ0,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0035085; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018; GO:0031514,ATP binding; ATP catabolic process; ATPase activity; cilium axoneme; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement; motile cilium,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,9.00E-57,CHOYP_DNAH5.2.2,,,,,,,DYH8_MOUSE,Mus musculus (Mouse),microtubule-based movement [GO:0007018] comp81394_c0_seq1,433,43.649,0.43799292,6,13,,8.00E-35,Q2HZX7,Protein fuzzy homolog (Xfy),Protein fuzzy homolog (Xfy),GO:0042384; GO:0005737; GO:0005856; GO:0010172; GO:0048704; GO:0001736; GO:0001843; GO:0015031; GO:0008589,cilium assembly; cytoplasm; cytoskeleton; embryonic body morphogenesis; embryonic skeletal system morphogenesis; establishment of planar polarity; neural tube closure; protein transport; regulation of smoothened signaling pathway,,1.00E-24,CHOYP_FUZZY.1.1,,,,,,,FUZZY_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cilium assembly [GO:0042384]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589] comp81422_c0_seq1,226,43.8053,1.05807156,0,24,,4.00E-09,Q80Z71,Tenascin-N (TN-N),Tenascin-N (TN-N),GO:0007409; GO:0016049; GO:0016477; GO:0009986; GO:0007160; GO:0042802; GO:0005178; GO:0005578,axonogenesis; cell growth; cell migration; cell surface; cell-matrix adhesion; identical protein binding; integrin binding; proteinaceous extracellular matrix,PF00147;PF00041;,,,,,,,,,TENN_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell growth [GO:0016049]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477] comp81434_c0_seq1,653,42.879,1.14950642,6,31,,3.00E-06,P35969,Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT),Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT),GO:0005524; GO:0005794; GO:0036326; GO:0036327; GO:0030154; GO:0016477; GO:0048598; GO:0005768; GO:0005887; GO:0002548; GO:0005634; GO:0001569; GO:0036332; GO:0043406; GO:0045766; GO:0030335; GO:0043552; GO:0014068; GO:0010863; GO:0030949; GO:0046777; GO:0002040; GO:0048010; GO:0005021,ATP binding; Golgi apparatus; VEGF-A-activated receptor activity; VEGF-B-activated receptor activity; cell differentiation; cell migration; embryonic morphogenesis; endosome; integral to plasma membrane; monocyte chemotaxis; nucleus; patterning of blood vessels; placental growth factor-activated receptor activity; positive regulation of MAP kinase activity; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phospholipase C activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein autophosphorylation; sprouting angiogenesis; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor-activated receptor activity,PF07679;PF07714;,,,,,,,,,VGFR1_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; patterning of blood vessels [GO:0001569]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; post-embryonic camera-type eye morphogenesis [GO:0048597]; protein autophosphorylation [GO:0046777]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp81444_c1_seq1,1355,43.1734,0.40002854,48,134,,5.00E-160,Q0IHY4,TBC1 domain family member 12,TBC1 domain family member 12,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,5.00E-136,CHOYP_LOC100551549.1.1,,,,,,,TBC12_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of autophagosome assembly [GO:2000785]; regulation of vesicle fusion [GO:0031338] comp81454_c0_seq2,1327,34.9661,0.52635781,35,45,,1.00E-67,Q5RDU7,Protein yippee-like 5,Protein yippee-like 5,,,PF03226;,3.00E-68,CHOYP_LOC100372803.2.2,,,,,,,YPEL5_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp81464_c0_seq1,221,47.5113,0.24165952,0,13,,5.00E-19,Q9QXE5,Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16),Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16),GO:0016023; GO:0005768; GO:0005764; GO:0006508; GO:0008236,cytoplasmic membrane-bounded vesicle; endosome; lysosome; proteolysis; serine-type peptidase activity,PF05577;,2.00E-18,CHOYP_LOC100377982.1.1,,,,,,,TSSP_MOUSE,Mus musculus (Mouse),proteolysis [GO:0006508] comp81466_c0_seq1,538,44.2379,0.85278971,17,18,,2.00E-42,P0CI65,Nephrocystin-3,Nephrocystin-3,GO:0016055; GO:0060271; GO:0072372,Wnt receptor signaling pathway; cilium morphogenesis; primary cilium,PF13176;,4.00E-31,CHOYP_NPHP3.1.1,,,,,,,NPHP3_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; Wnt signaling pathway [GO:0016055] comp81479_c0_seq1,352,42.3295,0.59830991,8,2,,2.00E-25,Q96JC1,Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p),Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p),GO:0030897; GO:0031902; GO:0005765; GO:0015031; GO:0005083,HOPS complex; late endosome membrane; lysosomal membrane; protein transport; small GTPase regulator activity,PF00780;PF10366;PF10367;,,,,,,,,,VPS39_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]" comp81519_c0_seq1,246,36.1789,1.20294196,1,7,,7.00E-14,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp81566_c0_seq1,223,60.5381,1.28002574,1,2,,8.00E-14,P65441,Protein mrp homolog,,GO:0005524; GO:0040007,ATP binding; growth,,,,,,,,,,MRP_MYCTU,, comp81632_c1_seq1,530,44.1509,0.73449889,6,60,,3.00E-28,Q9HAS3,Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3),Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3),GO:0016021; GO:0001882; GO:0005886; GO:0015390; GO:0015864; GO:0015389; GO:0055085,integral to membrane; nucleoside binding; plasma membrane; purine-specific nucleoside:sodium symporter activity; pyrimidine nucleoside transport; pyrimidine- and adenine-specific:sodium symporter activity; transmembrane transport,PF07670;PF07662;PF01773;,,,,,,,,,S28A3_HUMAN,Homo sapiens (Human),pyrimidine nucleoside transport [GO:0015864]; retina homeostasis [GO:0001895] comp81669_c1_seq1,218,46.789,0.92620173,5,0,,1.00E-08,O15417,Trinucleotide repeat-containing gene 18 protein (Long CAG trinucleotide repeat-containing gene 79 protein),Trinucleotide repeat-containing gene 18 protein (Long CAG trinucleotide repeat-containing gene 79 protein),GO:0003677,DNA binding,PF01426;,,,,,,,,,TNC18_HUMAN,Homo sapiens (Human),chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507] comp81671_c0_seq1,224,62.9464,1.15268691,0,5,,4.00E-14,Q9HXZ3,tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase),tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase),GO:0005524; GO:0005737; GO:0016879; GO:0006400,"ATP binding; cytoplasm; ligase activity, forming carbon-nitrogen bonds; tRNA modification",PF01171;PF09179;PF11734;,,,,,,,,,TILS_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),tRNA modification [GO:0006400] comp81677_c0_seq1,423,37.1158,0.90065863,4,50,,6.00E-11,P24464,Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8) (Cytochrome P450-KP1) (Cytochrome P450-PP1),Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8) (Cytochrome P450-KP1) (Cytochrome P450-PP1),GO:0019369; GO:0070330; GO:0005789; GO:0020037; GO:0043231; GO:0005506; GO:0001822; GO:0048252; GO:0004497; GO:0033574,arachidonic acid metabolic process; aromatase activity; endoplasmic reticulum membrane; heme binding; intracellular membrane-bounded organelle; iron ion binding; kidney development; lauric acid metabolic process; monooxygenase activity; response to testosterone stimulus,PF00067;,,,,,,,,,CP4AC_RAT,Rattus norvegicus (Rat),arachidonic acid metabolic process [GO:0019369]; fatty acid metabolic process [GO:0006631]; kidney development [GO:0001822]; lauric acid metabolic process [GO:0048252]; response to testosterone [GO:0033574] comp81733_c0_seq1,617,37.4392,0.41694262,27,40,,9.00E-20,Q9IB61,Bladder cancer-associated protein (ZfBc10),Bladder cancer-associated protein (ZfBc10),GO:0016021,integral to membrane,,8.00E-28,CHOYP_PHUM_PHUM520920.1.1,,,,,,,BLCAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp81739_c0_seq1,299,58.194,0.76122646,0,15,,2.00E-19,O32222,Copper-sensing transcriptional repressor CsoR (Copper-sensitive operon repressor),Copper-sensing transcriptional repressor CsoR (Copper-sensitive operon repressor),GO:0003677; GO:0005737; GO:0046872; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF02583;,,,,,,,,,CSOR_BACSU,Bacillus subtilis (strain 168),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp81775_c0_seq1,485,43.9175,0.56613144,11,51,,1.00E-63,Q62902,Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58),Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58),GO:0006888; GO:0005794; GO:0000139; GO:0005509; GO:0005783; GO:0005789; GO:0005793; GO:0033116; GO:0042802; GO:0016021; GO:0005537; GO:0015031,ER to Golgi vesicle-mediated transport; Golgi apparatus; Golgi membrane; calcium ion binding; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; identical protein binding; integral to membrane; mannose binding; protein transport,PF03388;,8.00E-58,CHOYP_LOC660183.1.1,,,,,,,LMAN1_RAT,Rattus norvegicus (Rat),ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] comp81779_c0_seq1,509,44.7937,0.36559281,21,5,,,,,,,,,5.00E-17,CHOYP_MPHOSPH9.1.1,,,,,,,,, comp81784_c0_seq1,206,71.3592,1.16513065,0,4,,2.00E-13,Q9HZP5,Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase),Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase),GO:0051539; GO:0004174; GO:0006091; GO:0046872,"4 iron, 4 sulfur cluster binding; electron-transferring-flavoprotein dehydrogenase activity; generation of precursor metabolites and energy; metal ion binding",PF05187;,,,,,,,,,ETFD_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), comp81804_c1_seq1,221,52.4887,0.79405501,0,8,,5.00E-16,P00919,Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II),Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II),GO:0038166; GO:0045177; GO:0015670; GO:0004089; GO:0005737; GO:0005829; GO:0002009; GO:0006730; GO:0005886; GO:2001150; GO:0044070; GO:0051453; GO:0046903; GO:0008270,angiotensin-mediated signaling pathway; apical part of cell; carbon dioxide transport; carbonate dehydratase activity; cytoplasm; cytosol; morphogenesis of an epithelium; one-carbon metabolic process; plasma membrane; positive regulation of dipeptide transmembrane transport; regulation of anion transport; regulation of intracellular pH; secretion; zinc ion binding,PF00194;,,,,,,,,,CAH2_RABIT,Oryctolagus cuniculus (Rabbit),"angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; one-carbon metabolic process [GO:0006730]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; secretion [GO:0046903]" comp81840_c0_seq1,422,43.8389,0.80822044,15,10,,1.00E-87,Q8MQJ9,Brain tumor protein,Brain tumor protein,GO:0008356; GO:0055060; GO:0007411; GO:0007420; GO:0005737; GO:0007402; GO:0007406; GO:0048477; GO:0006909; GO:0009303; GO:0035282; GO:0030371; GO:0008270,asymmetric cell division; asymmetric neuroblast division resulting in ganglion mother cell formation; axon guidance; brain development; cytoplasm; ganglion mother cell fate determination; negative regulation of neuroblast proliferation; oogenesis; phagocytosis; rRNA transcription; segmentation; translation repressor activity; zinc ion binding,PF01436;PF00643;,5.00E-92,CHOYP_LOC100902046.1.1,,,,,,,BRAT_DROME,Drosophila melanogaster (Fruit fly),asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419] comp81859_c0_seq1,479,44.0501,0.34520107,3,44,,3.00E-11,Q96ME1,F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18),F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18),,,PF00646;,,,,,,,,,FXL18_HUMAN,Homo sapiens (Human), comp81888_c0_seq1,217,45.1613,0.93967513,13,0,,1.00E-08,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp81891_c0_seq1,306,51.634,0.79329013,7,2,,,,,,,,,9.00E-17,CHOYP_LOC590385.1.1,,,,,,,,, comp81893_c0_seq1,474,48.7342,0.32220523,8,16,,4.00E-29,Q5SYL3,UPF0378 protein KIAA0100,Protein KIAA0100,GO:0005576,extracellular region,PF10351;PF10344;PF10347;,3.00E-32,CHOYP_LOC100165500.1.1,,,,,,,K0100_MOUSE,Mus musculus (Mouse), comp8189_c0_seq1,457,48.5777,0.57441747,6,7,,4.00E-21,Q6ZNJ1,Neurobeachin-like protein 2,Neurobeachin-like protein 2,GO:0005783; GO:0030220,endoplasmic reticulum; platelet formation,PF02138;PF15787;PF14844;PF00400;,6.00E-15,CHOYP_NBEL1.1.1,,,,,,,NBEL2_HUMAN,Homo sapiens (Human),platelet formation [GO:0030220] comp8194_c0_seq1,284,45.0704,0.34867083,8,0,,3.00E-22,Q9QZ05,Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2),eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2),GO:0005524; GO:0009267; GO:0022626; GO:0030968; GO:0004694; GO:0017148; GO:0043558,ATP binding; cellular response to starvation; cytosolic ribosome; endoplasmic reticulum unfolded protein response; eukaryotic translation initiation factor 2alpha kinase activity; negative regulation of translation; regulation of translational initiation in response to stress,PF12745;PF00069;PF05773;,2.00E-13,CHOYP_E2AK4.1.1,,,,,,,E2AK4_MOUSE,Mus musculus (Mouse),adaptive immune response [GO:0002250]; cell cycle arrest [GO:0007050]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; induction by virus of host autophagy [GO:0039520]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] comp81950_c0_seq1,241,55.6017,1.0325801,0,17,,3.00E-49,Q6A5H2,Alanine racemase (EC 5.1.1.1),Alanine racemase (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),D-alanine biosynthetic process [GO:0030632] comp81961_c0_seq1,753,44.6215,0.56172939,26,23,,7.00E-65,Q9BZ29,Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1),Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1),GO:0005089; GO:0007596; GO:0005829; GO:0012505; GO:0016020; GO:0005543; GO:0007264,Rho guanyl-nucleotide exchange factor activity; blood coagulation; cytosol; endomembrane system; membrane; phospholipid binding; small GTPase mediated signal transduction,PF06920;PF14429;PF11878;PF00169;,2.00E-30,CHOYP_DOCK9.1.2,,,,,,,DOCK9_HUMAN,Homo sapiens (Human),blood coagulation [GO:0007596]; small GTPase mediated signal transduction [GO:0007264] comp81978_c0_seq1,274,59.854,1.06479453,3,12,,2.00E-20,A0R4M9,Trehalose-phosphate synthase (TPS) (EC 2.4.1.-) (Trehalose-6-phosphate synthase),Trehalose-phosphate synthase (TPS) (EC 2.4.1.-) (Trehalose-6-phosphate synthase),GO:0016757; GO:0005992,"transferase activity, transferring glycosyl groups; trehalose biosynthetic process",PF00982;,,,,,,,,,OTSA_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),trehalose biosynthetic process [GO:0005992] comp81983_c0_seq1,310,42.9032,0.56264719,0,22,,6.00E-12,Q6DCW1,Zinc finger protein Gfi-1b (Growth factor independent protein 1B),Zinc finger protein Gfi-1b (Growth factor independent protein 1B),GO:0003677; GO:0016568; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,GFI1B_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp8201_c0_seq1,294,44.2177,0.9131058,7,4,,9.00E-17,Q9VFD5,Protein fem-1 homolog CG6966,Protein fem-1 homolog CG6966,GO:0051438; GO:0004842,regulation of ubiquitin-protein ligase activity; ubiquitin-protein ligase activity,PF12796;PF13606;,,,,,,,,,FEM1A_DROME,Drosophila melanogaster (Fruit fly),regulation of ubiquitin-protein transferase activity [GO:0051438] comp82033_c1_seq1,601,62.5624,1.19638068,2,26,,6.00E-23,Q82DT3,NADH-quinone oxidoreductase subunit I 2 (EC 1.6.99.5) (NADH dehydrogenase I subunit I 2) (NDH-1 subunit I 2),NADH-quinone oxidoreductase subunit I 2 (EC 1.6.5.11) (NADH dehydrogenase I subunit I 2) (NDH-1 subunit I 2),GO:0051539; GO:0050136; GO:0005506; GO:0005886; GO:0048038,"4 iron, 4 sulfur cluster binding; NADH dehydrogenase (quinone) activity; iron ion binding; plasma membrane; quinone binding",PF00037;,,,,,,,,,NUOI2_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680), comp82051_c1_seq1,238,46.6387,0.47421472,3,12,,7.00E-22,P51798,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0005254; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; chloride channel activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,7.00E-23,CHOYP_CLCN7.3.3,,,,,,,CLCN7_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810] comp82057_c0_seq1,428,36.9159,1.30793397,0,47,,,,,,,,,,,4.00E-14,ruditapes_c9625,,,,,,, comp82064_c0_seq1,531,43.8795,0.74974305,2,85,,6.00E-14,Q01177,"Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]","Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]",GO:0006915; GO:0007596; GO:0004175; GO:0022617; GO:0005615; GO:0031232; GO:0042730; GO:0043231; GO:0060716; GO:0071674; GO:0046716; GO:0045445; GO:0010812; GO:0051918; GO:0005886; GO:0051919; GO:0051603; GO:0004252; GO:0042246; GO:0048771; GO:0060707,apoptotic process; blood coagulation; endopeptidase activity; extracellular matrix disassembly; extracellular space; extrinsic to external side of plasma membrane; fibrinolysis; intracellular membrane-bounded organelle; labyrinthine layer blood vessel development; mononuclear cell migration; muscle cell cellular homeostasis; myoblast differentiation; negative regulation of cell-substrate adhesion; negative regulation of fibrinolysis; plasma membrane; positive regulation of fibrinolysis; proteolysis involved in cellular protein catabolic process; serine-type endopeptidase activity; tissue regeneration; tissue remodeling; trophoblast giant cell differentiation,PF00051;PF00024;PF00089;,,,,,,,,,PLMN_RAT,Rattus norvegicus (Rat),blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trophoblast giant cell differentiation [GO:0060707] comp82073_c0_seq1,230,53.4783,1.22159898,0,10,,1.00E-48,Q6A964,Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS),Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS),GO:0005524; GO:0005737; GO:0004820; GO:0006426; GO:0046983,ATP binding; cytoplasm; glycine-tRNA ligase activity; glycyl-tRNA aminoacylation; protein dimerization activity,PF03129;PF00587;,,,,,,,,,SYG_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glycyl-tRNA aminoacylation [GO:0006426] comp82088_c1_seq1,435,43.4483,0.40286653,14,7,,3.00E-07,Q5XJ85,Myeloid differentiation primary response protein MyD88,Myeloid differentiation primary response protein MyD88,GO:0002755; GO:0002218; GO:0005737; GO:0006954; GO:0045087; GO:0043123; GO:0002237,MyD88-dependent toll-like receptor signaling pathway; activation of innate immune response; cytoplasm; inflammatory response; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; response to molecule of bacterial origin,PF00531;PF01582;,,,,,,,,,MYD88_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),activation of innate immune response [GO:0002218]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237] comp82093_c0_seq1,215,41.8605,0.74705173,7,0,,4.00E-13,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp82097_c0_seq1,265,43.3962,0.40598869,2,9,,6.00E-21,Q8AV57,Protein sidekick-2,Protein sidekick-2,GO:0007155; GO:0030054; GO:0016021; GO:0005886; GO:0045202,cell adhesion; cell junction; integral to membrane; plasma membrane; synapse,PF00041;PF07679;,,,,,,,,,SDK2_CHICK,Gallus gallus (Chicken),camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] comp82102_c1_seq1,203,45.8128,0.66112715,4,0,,6.00E-09,Q6TCH7,Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG),Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG),GO:0000139; GO:0016021,Golgi membrane; integral to membrane,PF03006;,,,,,,,,,PAQR3_HUMAN,Homo sapiens (Human),MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein phosphorylation [GO:0001933]; protein localization to Golgi apparatus [GO:0034067] comp82118_c0_seq1,333,46.5465,0.44504066,4,0,,7.00E-08,Q4P6L3,Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1),GO:0000139; GO:0031901; GO:0016021; GO:0016746; GO:0008270,"Golgi membrane; early endosome membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF12796;PF01529;,,,,,,,,,AKR1_USTMA,Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus), comp82123_c0_seq1,347,44.9568,0.23065643,11,0,,3.00E-16,A6H8Z2,Protein FAM221B,Protein FAM221B,,,PF14753;,1.00E-59,CHOYP_LOC100368368.1.1,,,,,,,F221B_HUMAN,Homo sapiens (Human), comp82153_c0_seq1,547,35.2834,0.48678821,28,7,,5.00E-33,Q9CQU8,Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein),Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein),GO:0042720; GO:0005739; GO:0006627; GO:0006508; GO:0008236,mitochondrial inner membrane peptidase complex; mitochondrion; protein processing involved in protein targeting to mitochondrion; proteolysis; serine-type peptidase activity,PF00717;PF10502;,,,,,,,,,IMP1L_MOUSE,Mus musculus (Mouse),mitochondrial respiratory chain complex assembly [GO:0033108]; protein processing involved in protein targeting to mitochondrion [GO:0006627]; signal peptide processing [GO:0006465] comp82171_c0_seq1,545,48.4404,0.37866393,33,0,,3.00E-24,Q9QYP0,Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4),GO:0005509; GO:0071907; GO:0061371; GO:0016021; GO:0005634; GO:0004872,calcium ion binding; determination of digestive tract left/right asymmetry; determination of heart left/right asymmetry; integral to membrane; nucleus; receptor activity,PF00431;PF12947;PF07645;PF00053;PF01437;,,,,,,,,,MEGF8_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] comp82176_c0_seq1,238,48.3193,0.57940417,5,10,,1.00E-15,Q8JG54,Repulsive guidance molecule A,Repulsive guidance molecule A,GO:0031225; GO:0005886,anchored to membrane; plasma membrane,PF06534;PF06535;,,,,,,,,,RGMA_CHICK,Gallus gallus (Chicken),BMP signaling pathway [GO:0030509] comp82186_c0_seq1,817,39.7797,0.06948702,43,18,,,,,,,,,3.00E-16,CHOYP_GLIPR1.3.3,4.00E-18,ruditapes_c23151,,,,,,, comp82199_c0_seq1,659,42.9439,0.40170512,17,45,,2.00E-28,O88480,Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN),GO:0016568; GO:0005737; GO:0060548; GO:0005634; GO:0019904; GO:0030346; GO:0004864,chromatin modification; cytoplasm; negative regulation of cell death; nucleus; protein domain specific binding; protein phosphatase 2B binding; protein phosphatase inhibitor activity,PF09047;,,,,,,,,,CABIN_RAT,Rattus norvegicus (Rat),chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823] comp82260_c1_seq1,488,46.3115,0.26815624,9,32,,4.00E-47,Q9P2S5,WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene),GO:0005813; GO:0005737,centrosome; cytoplasm,PF12894;,1.00E-29,CHOYP_LOC100368359.2.2,,,,,,,WRP73_HUMAN,Homo sapiens (Human),cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857] comp82262_c0_seq1,380,44.7368,0.73010529,13,3,,5.00E-57,Q8TBZ3,WD repeat-containing protein 20 (Protein DMR),WD repeat-containing protein 20 (Protein DMR),,,PF00400;,6.00E-58,CHOYP_WDR20.1.1,,,,,,,WDR20_HUMAN,Homo sapiens (Human), comp82271_c0_seq1,351,44.7293,0.17742079,6,10,,9.00E-21,B4F785,"Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)","Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)",GO:0030054; GO:0005578; GO:0045202,cell junction; proteinaceous extracellular matrix; synapse,PF00008;PF00041;PF00054;,,,,,,,,,EGFLA_RAT,Rattus norvegicus (Rat), comp82334_c0_seq1,462,41.9913,0.58319293,11,15,,1.00E-09,B4MXW3,Kelch-like protein diablo,Kelch-like protein diablo,GO:0016049; GO:0016567; GO:0050807,cell growth; protein ubiquitination; regulation of synapse organization,PF07707;PF00651;PF01344;,,,,,,,,,KLHDB_DROWI,Drosophila willistoni (Fruit fly),cell growth [GO:0016049]; protein ubiquitination [GO:0016567]; regulation of synapse organization [GO:0050807] comp82371_c0_seq1,423,41.3712,0.2218746,2,50,,1.00E-20,Q8VBT2,L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19),L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19),GO:0003941; GO:0006565; GO:0004794; GO:0006094; GO:0005739; GO:0030170; GO:0042866; GO:0043200; GO:0033590,L-serine ammonia-lyase activity; L-serine catabolic process; L-threonine ammonia-lyase activity; gluconeogenesis; mitochondrion; pyridoxal phosphate binding; pyruvate biosynthetic process; response to amino acid stimulus; response to cobalamin,PF00291;,,,,,,,,,SDHL_MOUSE,Mus musculus (Mouse),gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; pyruvate biosynthetic process [GO:0042866] comp82381_c0_seq1,258,43.4109,0.50340892,1,22,,2.00E-20,Q75WS4,Cryptochrome DASH,Cryptochrome DASH,GO:0003913; GO:0006281; GO:0018298,DNA photolyase activity; DNA repair; protein-chromophore linkage,PF00875;PF03441;,,,,,,,,,CRYD_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298] comp82397_c0_seq1,206,66.9903,1.0443803,0,13,,2.00E-11,Q8K9C8,GTP-binding protein TypA/BipA homolog,GTP-binding protein TypA/BipA homolog,GO:0005525; GO:0006184; GO:0003924,GTP binding; GTP catabolic process; GTPase activity,PF00679;PF03144;,,,,,,,,,TYPA_BUCAP,Buchnera aphidicola subsp. Schizaphis graminum (strain Sg), comp82403_c0_seq1,219,61.1872,0.94146107,0,13,,3.00E-09,Q6A8I2,3-dehydroquinate synthase (EC 4.2.3.4),3-dehydroquinate synthase (EC 4.2.3.4),GO:0003856; GO:0009073; GO:0009423; GO:0005737,3-dehydroquinate synthase activity; aromatic amino acid family biosynthetic process; chorismate biosynthetic process; cytoplasm,PF01761;,,,,,,,,,AROB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423] comp82418_c0_seq1,528,46.0227,0.50271698,11,30,,2.00E-62,Q8CHN6,Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase),GO:0016831; GO:0019752; GO:0006672; GO:0005789; GO:0097194; GO:0016021; GO:0030170; GO:0008117,carboxy-lyase activity; carboxylic acid metabolic process; ceramide metabolic process; endoplasmic reticulum membrane; execution phase of apoptosis; integral to membrane; pyridoxal phosphate binding; sphinganine-1-phosphate aldolase activity,PF00282;,3.00E-83,CHOYP_SGPL1.1.1,,,,,,,SGPL1_RAT,Rattus norvegicus (Rat),androgen metabolic process [GO:0008209]; apoptotic signaling pathway [GO:0097190]; ceramide metabolic process [GO:0006672]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; fatty acid metabolic process [GO:0006631]; fibroblast migration [GO:0010761]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; regulation of multicellular organism growth [GO:0040014]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]; sphingolipid catabolic process [GO:0030149]; vasculogenesis [GO:0001570] comp82420_c0_seq1,603,45.1078,0.93066512,4,29,,8.00E-33,Q9Y2M2,Protein SSUH2 homolog (Protein ssu-2 homolog),Protein SSUH2 homolog (Protein ssu-2 homolog),GO:0005737,cytoplasm,,,,2.00E-13,ruditapes_c15961,,,,,CC032_HUMAN,Homo sapiens (Human), comp82424_c0_seq1,485,44.7423,0.78923412,10,22,,6.00E-27,Q9VHA0,Polycomb protein Scm (Sex comb on midleg protein),Polycomb protein Scm (Sex comb on midleg protein),GO:0035102; GO:0007409; GO:0016568; GO:0016458; GO:0030708; GO:0045892; GO:0030713; GO:0005700; GO:0006351; GO:0008270,"PRC1 complex; axonogenesis; chromatin modification; gene silencing; germarium-derived female germ-line cyst encapsulation; negative regulation of transcription, DNA-dependent; ovarian follicle cell stalk formation; polytene chromosome; transcription, DNA-dependent; zinc ion binding",PF12140;PF02820;PF00536;PF06467;,1.00E-18,CHOYP_SCMH1.1.1,,,,,,,SCM_DROME,Drosophila melanogaster (Fruit fly),"axonogenesis [GO:0007409]; chromatin modification [GO:0016568]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]" comp82486_c0_seq1,239,43.5146,0.46083756,6,0,,7.00E-07,Q5EB73,Transmembrane protein 246,Transmembrane protein 246,GO:0016021,integral to membrane,,,,,,,,,,TM246_RAT,Rattus norvegicus (Rat), comp82490_c0_seq1,319,44.8276,0.31335991,2,38,,1.00E-57,P58375,60S ribosomal protein L30,60S ribosomal protein L30,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01248;,3.00E-112,CHOYP_DC1I2.2.3,3.00E-78,ruditapes2_c4916,,,,,RL30_SPOFR,Spodoptera frugiperda (Fall armyworm),translation [GO:0006412] comp82534_c1_seq1,276,45.6522,0.35467815,4,0,,,,,,,,,2.00E-18,CHOYP_BRAFLDRAFT_120072.1.1,,,,,,,,, comp82553_c0_seq1,375,52.8,0.93688374,0,42,,6.00E-36,P27639,Eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Initiation factor 1),Eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Initiation factor 1),GO:0005524; GO:0008026; GO:0003743,ATP binding; ATP-dependent helicase activity; translation initiation factor activity,PF00270;PF00271;,2.00E-27,CHOYP_EF1A.3.4,5.00E-25,ruditapes_c8263,,,,,IF4A_CAEEL,Caenorhabditis elegans,regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; translational initiation [GO:0006413] comp82571_c0_seq2,304,38.4868,0.47068411,1,17,,2.00E-14,Q4ZHG4,Fibronectin type III domain-containing protein 1 (Activation-associated cDNA protein) (Expressed in synovial lining protein),Fibronectin type III domain-containing protein 1 (Activation-associated cDNA protein) (Expressed in synovial lining protein),GO:0005911; GO:0071456; GO:0005576; GO:0031966; GO:0005886; GO:0010666; GO:0001934; GO:0051223,cell-cell junction; cellular response to hypoxia; extracellular region; mitochondrial membrane; plasma membrane; positive regulation of cardiac muscle cell apoptotic process; positive regulation of protein phosphorylation; regulation of protein transport,PF00041;,,,,,,,,,FNDC1_HUMAN,Homo sapiens (Human), comp82592_c0_seq1,423,39.9527,0.7198682,10,44,,2.00E-16,Q8CJ44,Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter),Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter),GO:0016323; GO:0015137; GO:0016021; GO:0017153; GO:0015141,basolateral plasma membrane; citrate transmembrane transporter activity; integral to membrane; sodium:dicarboxylate symporter activity; succinate transmembrane transporter activity,PF00939;,,,,,,,,,S13A5_RAT,Rattus norvegicus (Rat),citrate transport [GO:0015746]; succinate transport [GO:0015744] comp82609_c0_seq1,392,64.7959,1.14698958,0,15,,1.00E-76,Q6A9Z4,Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) (Glutamine-synthetase adenylyltransferase) (ATase) ([Glutamate--ammonia-ligase] adenylyltransferase),Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) (Glutamine-synthetase adenylyltransferase) (ATase) ([Glutamate--ammonia-ligase] adenylyltransferase),GO:0005524; GO:0008882,ATP binding; [glutamate-ammonia-ligase] adenylyltransferase activity,PF08335;PF03710;,,,,,,,,,GLNE_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp82641_c0_seq1,763,43.6435,0.30337212,23,9,,5.00E-28,Q80TY5,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog),GO:0015031,protein transport,PF12624;PF06650;PF16909;,,,,,,,,,VP13B_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp82669_c1_seq1,664,40.9639,0.56143539,16,45,,1.00E-32,Q02338,"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase)","D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)",GO:0003858; GO:0060612; GO:0007420; GO:0044255; GO:0046951; GO:0046952; GO:0001889; GO:0005743; GO:0005759; GO:0005634; GO:0005543; GO:0046686; GO:0051412; GO:0042493; GO:0032355; GO:0045471; GO:0060416; GO:0032868; GO:0007584; GO:0042594; GO:0009636,3-hydroxybutyrate dehydrogenase activity; adipose tissue development; brain development; cellular lipid metabolic process; ketone body biosynthetic process; ketone body catabolic process; liver development; mitochondrial inner membrane; mitochondrial matrix; nucleus; phospholipid binding; response to cadmium ion; response to corticosterone stimulus; response to drug; response to estradiol stimulus; response to ethanol; response to growth hormone stimulus; response to insulin stimulus; response to nutrient; response to starvation; response to toxic substance,PF00106;,3.00E-40,CHOYP_LOC100374321.1.1,,,,,,,BDH_HUMAN,Homo sapiens (Human),adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636] comp82672_c0_seq1,370,38.3784,0.44591672,3,9,,5.00E-07,P17023,Zinc finger protein 19 (Zinc finger protein KOX12),Zinc finger protein 19 (Zinc finger protein KOX12),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZNF19_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp82676_c0_seq1,353,36.8272,0.24172266,8,17,,,,,,,,,9.00E-18,CHOYP_contig_005392,,,,,,,,, comp82683_c0_seq1,302,48.0132,1.15561908,7,6,,5.00E-19,P17342,Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C),Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C),GO:0008528; GO:0007193; GO:0005887; GO:0016941; GO:0007194; GO:0002158; GO:0017046; GO:0007200; GO:0051000; GO:0035810; GO:0008217; GO:0033688; GO:0001501,G-protein coupled peptide receptor activity; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; integral to plasma membrane; natriuretic peptide receptor activity; negative regulation of adenylate cyclase activity; osteoclast proliferation; peptide hormone binding; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of nitric-oxide synthase activity; positive regulation of urine volume; regulation of blood pressure; regulation of osteoblast proliferation; skeletal system development,PF01094;,1.00E-39,CHOYP_GCY.4.4,,,,,,,ANPRC_HUMAN,Homo sapiens (Human),adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP-mediated signaling [GO:0019933]; negative regulation of smooth muscle cell proliferation [GO:0048662]; osteoclast proliferation [GO:0002158]; pancreatic juice secretion [GO:0030157]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of urine volume [GO:0035810]; regulation of blood pressure [GO:0008217]; regulation of osteoblast proliferation [GO:0033688]; skeletal system development [GO:0001501] comp82743_c0_seq1,500,44,0.49789019,14,15,,2.00E-67,B2LU20,Sideroflexin-1,Sideroflexin-1,GO:0008324; GO:0016021; GO:0055072; GO:0031966,cation transmembrane transporter activity; integral to membrane; iron ion homeostasis; mitochondrial membrane,PF03820;,1.00E-75,CHOYP_SFXN1.1.1,,,,,,,SFXN1_SHEEP,Ovis aries (Sheep),iron ion homeostasis [GO:0055072] comp82757_c0_seq1,471,48.1953,0.62003564,10,15,,,,,,,,,1.00E-30,CHOYP_LOC100882444.1.1,,,,,,,,, comp82757_c0_seq2,283,48.4099,0.50088809,0,0,,1.00E-22,A4IFD2,Forkhead box protein P1,Forkhead box protein P1,GO:0008301; GO:0055007; GO:0003682; GO:0005737; GO:0009790; GO:0033152; GO:0030324; GO:0046872; GO:0008045; GO:0005634; GO:0007389; GO:0050679; GO:0002639; GO:0002053; GO:0045893; GO:0002329; GO:0046982; GO:0042803; GO:0043565; GO:0003700; GO:0007519; GO:0048745; GO:0006351; GO:0021517,"DNA binding, bending; cardiac muscle cell differentiation; chromatin binding; cytoplasm; embryo development; immunoglobulin V(D)J recombination; lung development; metal ion binding; motor neuron axon guidance; nucleus; pattern specification process; positive regulation of epithelial cell proliferation; positive regulation of immunoglobulin production; positive regulation of mesenchymal cell proliferation; positive regulation of transcription, DNA-dependent; pre-B cell differentiation; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; skeletal muscle tissue development; smooth muscle tissue development; transcription, DNA-dependent; ventral spinal cord development",PF00250;PF16159;,7.00E-31,CHOYP_LOC100882444.1.1,,,,,,,FOXP1_BOVIN,Bos taurus (Bovine),"cardiac muscle cell differentiation [GO:0055007]; immunoglobulin V(D)J recombination [GO:0033152]; interleukin-21 secretion [GO:0072619]; in utero embryonic development [GO:0001701]; lung secretory cell differentiation [GO:0061140]; motor neuron axon guidance [GO:0008045]; negative regulation of lung goblet cell differentiation [GO:1901250]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pre-B cell differentiation [GO:0002329]; regulation of cardiac muscle cell proliferation [GO:0060043]; sarcomere organization [GO:0045214]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; T follicular helper cell differentiation [GO:0061470]; transcription, DNA-templated [GO:0006351]; ventral spinal cord development [GO:0021517]" comp82759_c0_seq1,302,64.2384,1.03757157,1,13,,5.00E-06,Q8Y652,Manganese transport system membrane protein MntC,Manganese transport system membrane protein MntC,GO:0005524; GO:0042626; GO:0016021; GO:0006811; GO:0005886,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; ion transport; plasma membrane",PF00950;,,,,,,,,,MNTC_LISMO,Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e),ion transport [GO:0006811]; response to zinc ion [GO:0010043] comp82760_c0_seq1,220,40.9091,1.11113407,0,5,,5.00E-08,Q8TB73,Protein NDNF (Neuron-derived neurotrophic factor),Protein NDNF (Neuron-derived neurotrophic factor),GO:0016049; GO:0031012; GO:0030198; GO:0005576; GO:0008201; GO:0043524; GO:0001764; GO:0019800; GO:0010811; GO:0010976,cell growth; extracellular matrix; extracellular matrix organization; extracellular region; heparin binding; negative regulation of neuron apoptotic process; neuron migration; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; positive regulation of cell-substrate adhesion; positive regulation of neuron projection development,PF10179;,,,,,,,,,NDNF_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; nitric oxide mediated signal transduction [GO:0007263]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of neuron projection development [GO:0010976]; response to ischemia [GO:0002931]; vascular wound healing [GO:0061042] comp82783_c0_seq1,505,49.1089,0.33123984,15,35,,6.00E-32,P53995,Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein),GO:0005680; GO:0051301; GO:0007067; GO:0070979,anaphase-promoting complex; cell division; mitosis; protein K11-linked ubiquitination,PF12859;PF01851;,,,,,,,,,APC1_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979] comp82784_c0_seq1,359,35.0975,0.45363255,5,16,,1.00E-08,P17036,Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25),Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25),GO:0003677; GO:0030154; GO:0045321; GO:0007275; GO:0005634; GO:0003700; GO:0006351; GO:0008270,"DNA binding; cell differentiation; leukocyte activation; multicellular organismal development; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZNF3_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; leukocyte activation [GO:0045321]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp82801_c0_seq1,213,58.216,0.96245508,0,9,,7.00E-09,Q44470,Putative tartrate transporter,Putative tartrate transporter,GO:0016021; GO:0005886; GO:0055085; GO:0005215,integral to membrane; plasma membrane; transmembrane transport; transporter activity,PF07690;,,,,,,,,,TUB4_AGRVI,Agrobacterium vitis (Rhizobium vitis),transmembrane transport [GO:0055085] comp82887_c0_seq1,358,36.5922,0.60120086,7,18,,1.00E-06,A2A935,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;,,,,,,,,,PRD16_MOUSE,Mus musculus (Mouse),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp82891_c0_seq1,474,46.4135,0.35436166,25,0,,1.00E-13,Q6ZMV9,Kinesin-like protein KIF6,Kinesin-like protein KIF6,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,1.00E-35,CHOYP_KIF6.1.1,,,,,,,KIF6_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp82905_c0_seq1,754,44.0318,0.2198366,15,43,,2.00E-67,Q9Y2E6,E3 ubiquitin-protein ligase DTX4 (EC 6.3.2.-) (Protein deltex-4) (Deltex4) (RING finger protein 155),E3 ubiquitin-protein ligase DTX4 (EC 6.3.2.-) (Protein deltex-4) (Deltex4) (RING finger protein 155),GO:0007219; GO:0005829; GO:0045087; GO:0016874; GO:0032481; GO:0016567; GO:0008270,Notch signaling pathway; cytosol; innate immune response; ligase activity; positive regulation of type I interferon production; protein ubiquitination; zinc ion binding,PF02825;PF00097;,3.00E-34,CHOYP_DTX4.1.1,,,,,,,DTX4_HUMAN,Homo sapiens (Human),Notch signaling pathway [GO:0007219]; regulation of type I interferon production [GO:0032479] comp82908_c0_seq1,440,45.9091,0.48626955,9,28,,1.00E-55,Q9UKM7,"Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)","Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)",GO:0030433; GO:0005509; GO:0005789; GO:0044322; GO:0016021; GO:0004571; GO:0009311; GO:0043687; GO:0018279; GO:0006457,"ER-associated protein catabolic process; calcium ion binding; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; integral to membrane; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; oligosaccharide metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; protein folding",PF01532;,6.00E-34,CHOYP_MA1B1.1.1,,,,,,,MA1B1_HUMAN,Homo sapiens (Human),"endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein alpha-1,2-demannosylation [GO:0036508]; trimming of terminal mannose on B branch [GO:0036509]" comp82908_c1_seq1,238,47.8992,0.51493676,5,1,,1.00E-11,Q9SXC9,Probable alpha-mannosidase I MNS5 (EC 3.2.1.-),Alpha-mannosidase I MNS5 (EC 3.2.1.-),GO:0005509; GO:0005789; GO:0016021; GO:0004571; GO:0006486,"calcium ion binding; endoplasmic reticulum membrane; integral to membrane; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; protein glycosylation",PF01532;,,,,,,,,,MNS5_ARATH,Arabidopsis thaliana (Mouse-ear cress),endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; N-glycan processing [GO:0006491] comp82944_c0_seq1,775,43.7419,0.57481577,35,0,,1.00E-78,Q6NUP7,Serine/threonine-protein phosphatase 4 regulatory subunit 4,Serine/threonine-protein phosphatase 4 regulatory subunit 4,GO:0005737; GO:0032515; GO:0019888; GO:0008287; GO:0080163,cytoplasm; negative regulation of phosphoprotein phosphatase activity; protein phosphatase regulator activity; protein serine/threonine phosphatase complex; regulation of protein serine/threonine phosphatase activity,,1.00E-108,CHOYP_PPP4R4.2.3,,,,,,,PP4R4_HUMAN,Homo sapiens (Human),negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163] comp82972_c0_seq1,434,41.9355,0.63066663,4,5,,2.00E-11,Q6NZG4,Nitric oxide-inducible gene protein,DNA damage-induced apoptosis suppressor protein (Nitric oxide-inducible gene protein),GO:0006915; GO:0034644; GO:0071345; GO:0071480; GO:0071447; GO:0005737; GO:0030097; GO:0071850; GO:2000270; GO:0005634; GO:0006974; GO:0007286,apoptotic process; cellular response to UV; cellular response to cytokine stimulus; cellular response to gamma radiation; cellular response to hydroperoxide; cytoplasm; hemopoiesis; mitotic cell cycle arrest; negative regulation of fibroblast apoptotic process; nucleus; response to DNA damage stimulus; spermatid development,PF08646;,,,,,,,,,NOXIN_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to hydroperoxide [GO:0071447]; cellular response to UV [GO:0034644]; hemopoiesis [GO:0030097]; mitotic cell cycle arrest [GO:0071850]; negative regulation of fibroblast apoptotic process [GO:2000270]; spermatid development [GO:0007286] comp83021_c1_seq1,284,60.2113,1.23085951,0,11,,5.00E-10,A7GMJ3,Lactate utilization protein B,Lactate utilization protein B,GO:0051539; GO:0019516; GO:0046872,"4 iron, 4 sulfur cluster binding; lactate oxidation; metal ion binding",PF02589;PF11870;PF13183;,,,,,,,,,LUTB_BACCN,Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98),lactate oxidation [GO:0019516] comp83033_c0_seq1,232,37.931,0.38072603,6,11,,,,,,,,,2.00E-16,CHOYP_SLFN5.1.1,,,,,,,,, comp83104_c0_seq1,672,45.5357,0.4315403,23,9,,2.00E-16,Q5U312,Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14),Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14),GO:0005938; GO:0005856; GO:0005634,cell cortex; cytoskeleton; nucleus,PF12796;,4.00E-70,CHOYP_LOC100367361.1.1,,,,,,,RAI14_RAT,Rattus norvegicus (Rat), comp83119_c0_seq1,312,41.0256,0.38671017,12,11,,9.00E-36,Q8AW42,Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13),Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13),GO:0000139; GO:0016021; GO:0046873; GO:0006829,Golgi membrane; integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,8.00E-43,CHOYP_BRAFLDRAFT_126133.1.1,,,,,,,S39AD_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular zinc ion homeostasis [GO:0006882]; zinc II ion transmembrane transport [GO:0071577]; zinc II ion transport [GO:0006829] comp83150_c0_seq1,337,44.8071,0.53387623,0,47,,2.00E-34,Q8BM89,Arylsulfatase J (ASJ) (EC 3.1.6.-),Arylsulfatase J (ASJ) (EC 3.1.6.-),GO:0005576; GO:0046872; GO:0008484,extracellular region; metal ion binding; sulfuric ester hydrolase activity,PF00884;,5.00E-40,CHOYP_BRAFLDRAFT_206907.8.11,,,,,,,ARSJ_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp83154_c0_seq1,322,46.8944,0.51506521,7,15,,9.00E-12,Q9Z1T6,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235),GO:0000285; GO:0016308; GO:0052810; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0030659; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0032288; GO:0048471; GO:0012506; GO:0008270,1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; myelin assembly; perinuclear region of cytoplasm; vesicle membrane; zinc ion binding,PF00118;PF00610;PF01363;PF01504;,2.00E-18,CHOYP_FYV1.1.1,,,,,,,FYV1_MOUSE,Mus musculus (Mouse),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp83157_c0_seq1,371,43.9353,0.40675085,15,5,,3.00E-43,Q91ZX7,Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)],GO:0035909; GO:0043277; GO:0097242; GO:0005509; GO:0008203; GO:0005905; GO:0005887; GO:0030178; GO:2000587; GO:0014912; GO:0005634; GO:0048471; GO:0010875; GO:0006898; GO:0032956; GO:0032429,aorta morphogenesis; apoptotic cell clearance; beta-amyloid clearance; calcium ion binding; cholesterol metabolic process; coated pit; integral to plasma membrane; negative regulation of Wnt receptor signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; negative regulation of smooth muscle cell migration; nucleus; perinuclear region of cytoplasm; positive regulation of cholesterol efflux; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,8.00E-19,CHOYP_LRP1.5.5,,,,,,,LRP1_MOUSE,Mus musculus (Mouse),aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429] comp83157_c1_seq1,339,48.0826,0.63433388,5,7,,3.00E-11,Q95RU0,Protein cueball,Protein cueball,GO:0044332; GO:0042813; GO:0017147; GO:0060070; GO:0016021; GO:0048477; GO:0005886; GO:0007285,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; Wnt-protein binding; canonical Wnt receptor signaling pathway; integral to membrane; oogenesis; plasma membrane; primary spermatocyte growth,PF00058;,,,,,,,,,CUE_DROME,Drosophila melanogaster (Fruit fly),oogenesis [GO:0048477]; primary spermatocyte growth [GO:0007285]; sleep [GO:0030431]; spermatogenesis [GO:0007283]; triglyceride homeostasis [GO:0070328] comp83162_c0_seq1,212,59.9057,1.29093781,0,4,,9.00E-08,P0A5Y0,Molybdate-binding protein,,GO:0044119; GO:0015412; GO:0030288; GO:0005886,growth of symbiont in host cell; molybdate transmembrane-transporting ATPase activity; outer membrane-bounded periplasmic space; plasma membrane,,,,,,,,,,MODA_MYCTU,, comp83165_c0_seq1,208,38.9423,1.01953576,3,13,,6.00E-08,Q5DRB6,Protocadherin gamma-A4 (PCDH-gamma-A4),Protocadherin gamma-A4 (PCDH-gamma-A4),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG4_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp83165_c1_seq1,233,42.4893,0.58017598,2,10,,2.00E-10,O35161,Cadherin EGF LAG seven-pass G-type receptor 1,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0004930; GO:0007266; GO:0009952; GO:0045176; GO:0005509; GO:0007267; GO:0007417; GO:0048105; GO:0042249; GO:0001702; GO:0001942; GO:0007156; GO:0042472; GO:0005887; GO:0060490; GO:0007626; GO:0001843; GO:0001764; GO:0007218; GO:0060488; GO:0090179; GO:0060489; GO:0046983; GO:0090251; GO:0032956; GO:0046928; GO:0042060,G-protein coupled receptor activity; Rho protein signal transduction; anterior/posterior pattern specification; apical protein localization; calcium ion binding; cell-cell signaling; central nervous system development; establishment of body hair planar orientation; establishment of planar polarity of embryonic epithelium; gastrulation with mouth forming second; hair follicle development; homophilic cell adhesion; inner ear morphogenesis; integral to plasma membrane; lateral sprouting involved in lung morphogenesis; locomotory behavior; neural tube closure; neuron migration; neuropeptide signaling pathway; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar cell polarity pathway involved in neural tube closure; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; protein dimerization activity; protein localization involved in establishment of planar polarity; regulation of actin cytoskeleton organization; regulation of neurotransmitter secretion; wound healing,PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;,,,,,,,,,CELR1_MOUSE,Mus musculus (Mouse),anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060] comp83165_c2_seq1,204,38.7255,0.79872049,2,10,,2.00E-11,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,,,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp83207_c0_seq1,249,57.8313,1.11703929,0,11,,5.00E-11,Q6A5H2,Alanine racemase (EC 5.1.1.1),Alanine racemase (EC 5.1.1.1),GO:0030632; GO:0008784; GO:0030170,D-alanine biosynthetic process; alanine racemase activity; pyridoxal phosphate binding,PF00842;PF01168;,,,,,,,,,ALR_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),D-alanine biosynthetic process [GO:0030632] comp83232_c0_seq1,585,27.8632,0.81219919,66,47,,,,,,,,,5.00E-43,CHOYP_ACTB3.1.1,,,,,,,,, comp83242_c0_seq1,509,44.9902,1.30183052,15,7,,,,,,,,,,,2.00E-19,ruditapes_c12248,,,,,,, comp83250_c0_seq1,212,43.8679,0.30342555,1,0,,2.00E-07,Q91WQ5,TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta),TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta),GO:0030914; GO:0043966; GO:0004402; GO:0006355; GO:0003713; GO:0033276; GO:0006351,"STAGA complex; histone H3 acetylation; histone acetyltransferase activity; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription factor TFTC complex; transcription, DNA-dependent",PF04494;PF00400;,,,,,,,,,TAF5L_MOUSE,Mus musculus (Mouse),"histone H3 acetylation [GO:0043966]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp83250_c1_seq1,232,43.5345,0.82625649,1,31,,4.00E-21,Q9JHB4,WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD),WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD),,,PF00400;,4.00E-20,CHOYP_WDR31.2.2,,,,,,,WDR31_MOUSE,Mus musculus (Mouse), comp83261_c0_seq1,238,45.3782,0.58661625,3,0,,1.00E-13,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp83308_c0_seq1,611,38.7889,0.78685925,15,19,,2.00E-31,Q6PKC3,Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1),Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1),GO:0045454; GO:0005789; GO:0016021,cell redox homeostasis; endoplasmic reticulum membrane; integral to membrane,PF00085;,2.00E-17,CHOYP_TXD11.1.1,,,,,,,TXD11_HUMAN,Homo sapiens (Human),cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp83338_c0_seq1,358,48.0447,0.44067447,13,36,,7.00E-13,Q63186,Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta),Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta),GO:0005851; GO:0005085; GO:0042552; GO:0032057; GO:0014003; GO:0001541; GO:0009749; GO:0009408; GO:0043434; GO:0003743; GO:0031369,eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor activity; myelination; negative regulation of translational initiation in response to stress; oligodendrocyte development; ovarian follicle development; response to glucose stimulus; response to heat; response to peptide hormone stimulus; translation initiation factor activity; translation initiation factor binding,PF01008;,,,,,,,,,EI2BD_RAT,Rattus norvegicus (Rat),cellular response to stimulus [GO:0051716]; hippocampus development [GO:0021766]; myelination [GO:0042552]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413] comp83342_c0_seq1,364,43.6813,0.98492807,0,21,,8.00E-52,P09034,Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase),Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase),GO:0005524; GO:0006953; GO:0007568; GO:0006526; GO:0000053; GO:0004055; GO:0070852; GO:0071418; GO:0071230; GO:0071242; GO:0071320; GO:0071549; GO:0071377; GO:0071346; GO:0071222; GO:0071400; GO:0071356; GO:0060539; GO:0005783; GO:0001822; GO:0001889; GO:0005764; GO:0007494; GO:0005741; GO:0005634; GO:0043204; GO:0042493; GO:0032355; GO:0060416; GO:0010046; GO:0007584; GO:0010043; GO:0015643; GO:0000050,ATP binding; acute-phase response; aging; arginine biosynthetic process; argininosuccinate metabolic process; argininosuccinate synthase activity; cell body fiber; cellular response to amine stimulus; cellular response to amino acid stimulus; cellular response to ammonium ion; cellular response to cAMP; cellular response to dexamethasone stimulus; cellular response to glucagon stimulus; cellular response to interferon-gamma; cellular response to lipopolysaccharide; cellular response to oleic acid; cellular response to tumor necrosis factor; diaphragm development; endoplasmic reticulum; kidney development; liver development; lysosome; midgut development; mitochondrial outer membrane; nucleus; perikaryon; response to drug; response to estradiol stimulus; response to growth hormone stimulus; response to mycotoxin; response to nutrient; response to zinc ion; toxic substance binding; urea cycle,PF00764;,,,,,,,,,ASSY_RAT,Rattus norvegicus (Rat),acute-phase response [GO:0006953]; aging [GO:0007568]; arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; aspartate metabolic process [GO:0006531]; cellular response to amine stimulus [GO:0071418]; cellular response to amino acid stimulus [GO:0071230]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to interferon-gamma [GO:0071346]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oleic acid [GO:0071400]; cellular response to tumor necrosis factor [GO:0071356]; citrulline metabolic process [GO:0000052]; diaphragm development [GO:0060539]; kidney development [GO:0001822]; liver development [GO:0001889]; midgut development [GO:0007494]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to mycotoxin [GO:0010046]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050] comp8334_c0_seq1,261,47.8927,0.47835861,3,7,,7.00E-13,Q8BFR2,Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2),Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07648;,7.00E-11,CHOYP_LOC659040.2.2,,,,,,,FSTL5_MOUSE,Mus musculus (Mouse), comp83359_c0_seq1,290,33.7931,0.50587303,2,19,,1.00E-06,O93567,Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF),GO:0003677; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF00651;PF00096;,,,,,,,,,ZBT7A_CHICK,Gallus gallus (Chicken),"transcription, DNA-templated [GO:0006351]" comp83367_c0_seq1,203,55.665,1.02644,0,5,,2.00E-10,P80064,4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) (EC 1.13.11.27),4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) (EC 1.13.11.27),GO:0003868; GO:0006559; GO:0046872; GO:0006572,4-hydroxyphenylpyruvate dioxygenase activity; L-phenylalanine catabolic process; metal ion binding; tyrosine catabolic process,PF00903;,,,,,,,,,HPPD_PSEUJ,Pseudomonas sp. (strain P.J. 874),L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp83368_c1_seq1,252,59.9206,1.20733609,1,15,,9.00E-15,Q9HZE0,NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2) (NAD(+)-dependent glutamate dehydrogenase),NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2) (NAD(+)-dependent glutamate dehydrogenase),GO:0006520; GO:0004352,cellular amino acid metabolic process; glutamate dehydrogenase (NAD+) activity,PF05088;,,,,,,,,,DHE2_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),glutamate catabolic process to 2-oxoglutarate [GO:0019551] comp83389_c0_seq1,411,37.9562,0.75735742,18,0,,9.00E-14,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp83392_c0_seq1,228,50.8772,0.51068201,0,8,,7.00E-12,Q556K3,Probable flavin-containing monoamine oxidase B (EC 1.4.3.4),Probable flavin-containing monoamine oxidase B (EC 1.4.3.4),GO:0016491,oxidoreductase activity,PF01593;,,,,,,,,,AOFB_DICDI,Dictyostelium discoideum (Slime mold), comp83396_c0_seq1,367,45.7766,0.31656149,4,12,,6.00E-41,Q5ZKV9,Coiled-coil domain-containing protein 132,Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50),,,PF10474;PF10475;,2.00E-38,CHOYP_CC132.1.1,,,,,,,CC132_CHICK,Gallus gallus (Chicken),endocytic recycling [GO:0032456]; protein transport [GO:0015031] comp83400_c0_seq1,276,43.8406,0.30273621,12,0,,1.00E-32,Q9D071,MMS19 nucleotide excision repair protein homolog (MET18 homolog) (MMS19-like protein),MMS19 nucleotide excision repair protein homolog (MET18 homolog) (MMS19-like protein),GO:0097361; GO:0006281; GO:0071817; GO:0007059; GO:0016226; GO:0005634; GO:0045893; GO:0003713; GO:0006351,"CIA complex; DNA repair; MMXD complex; chromosome segregation; iron-sulfur cluster assembly; nucleus; positive regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent",PF12460;,,,,,,,,,MMS19_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp83408_c0_seq1,202,56.9307,1.10595931,2,4,,1.00E-20,P52279,Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP),GO:0004177; GO:0005737; GO:0006508,aminopeptidase activity; cytoplasm; proteolysis,PF00561;,,,,,,,,,PIP_XANCI,Xanthomonas citri (Xanthomonas campestris pv. citri), comp83433_c0_seq1,230,40.4348,0.94673921,3,12,,5.00E-07,Q5ZIJ9,E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2),GO:0007219; GO:0005737; GO:0004842; GO:0008270,Notch signaling pathway; cytoplasm; ubiquitin-protein ligase activity; zinc ion binding,PF12796;PF06701;PF00569;,,,,,,,,,MIB2_CHICK,Gallus gallus (Chicken),Notch signaling pathway [GO:0007219] comp83444_c0_seq1,273,38.0952,0.81096168,3,28,,,,,,,,,2.00E-11,CHOYP_HSPA12A.2.27,,,,,,,,, comp83477_c0_seq1,219,45.2055,0.83264983,0,24,,1.00E-06,Q91ZU6,Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2),GO:0031673; GO:0030018; GO:0015629; GO:0030424; GO:0007409; GO:0005509; GO:0007155; GO:0005938; GO:0007050; GO:0016023; GO:0031122; GO:0005789; GO:0005925; GO:0030056; GO:0016021; GO:0014704; GO:0005882; GO:0045104; GO:0009898; GO:0046907; GO:0015630; GO:0035371; GO:0051010; GO:0060053; GO:0005635; GO:0005634; GO:0097038; GO:0042803; GO:0031110; GO:0008090; GO:0042383; GO:0001725,H zone; Z disc; actin cytoskeleton; axon; axonogenesis; calcium ion binding; cell adhesion; cell cortex; cell cycle arrest; cytoplasmic membrane-bounded vesicle; cytoplasmic microtubule organization; endoplasmic reticulum membrane; focal adhesion; hemidesmosome; integral to membrane; intercalated disc; intermediate filament; intermediate filament cytoskeleton organization; internal side of plasma membrane; intracellular transport; microtubule cytoskeleton; microtubule plus end; microtubule plus-end binding; neurofilament cytoskeleton; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; protein homodimerization activity; regulation of microtubule polymerization or depolymerization; retrograde axon cargo transport; sarcolemma; stress fiber,PF00307;PF13499;PF02187;PF00681;PF00435;,3.00E-14,CHOYP_DYST.1.2,6.00E-34,ruditapes_c22212,,,,,DYST_MOUSE,Mus musculus (Mouse),axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090] comp83506_c0_seq1,204,43.6275,0.27816137,4,6,,1.00E-18,Q8MV48,N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),GO:0000139; GO:0005795; GO:0016021; GO:0009312; GO:0004653; GO:0006486,Golgi membrane; Golgi stack; integral to membrane; oligosaccharide biosynthetic process; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,,,,,,,,,GALT7_DROME,Drosophila melanogaster (Fruit fly),oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] comp83536_c0_seq1,261,52.4904,0.68319125,11,0,,8.00E-14,Q9P215,Pogo transposable element with KRAB domain,Pogo transposable element with KRAB domain,GO:0003677; GO:0007275; GO:0005634; GO:0006355,"DNA binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent",PF09607;PF03184;PF03221;PF01352;,,,,,,,,,POGK_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]" comp83577_c0_seq1,359,47.6323,0.87379319,19,3,,9.00E-59,P23098,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,2.00E-64,CHOYP_DYHC.1.3,,,,,,,DYHC_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp83580_c1_seq1,401,47.6309,0.96172847,11,0,,5.00E-12,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp8358_c0_seq1,230,42.1739,0.39286457,3,4,,2.00E-15,Q562E7,WD repeat-containing protein 81,WD repeat-containing protein 81,GO:0010923; GO:0016772,"negative regulation of phosphatase activity; transferase activity, transferring phosphorus-containing groups",PF02138;PF00400;,,,1.00E-18,ruditapes_lrc17761,,,,,WDR81_HUMAN,Homo sapiens (Human),establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; negative regulation of phosphatase activity [GO:0010923]; neurogenesis [GO:0022008]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496] comp83601_c0_seq1,203,60.0985,0.88891046,0,1,,3.00E-15,Q6AK95,Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase),Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase),GO:0006189; GO:0005524; GO:0004639,'de novo' IMP biosynthetic process; ATP binding; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity,PF01259;,,,,,,,,,PUR7_DESPS,Desulfotalea psychrophila (strain LSv54 / DSM 12343),'de novo' IMP biosynthetic process [GO:0006189] comp83617_c0_seq1,910,39.7802,0.78923363,24,60,,3.00E-23,Q32L97,Vesicle-associated membrane protein 4 (VAMP-4),Vesicle-associated membrane protein 4 (VAMP-4),GO:0005794; GO:0016021; GO:0016192,Golgi apparatus; integral to membrane; vesicle-mediated transport,PF00957;,8.00E-30,CHOYP_LOC100081619.1.1,,,,,,,VAMP4_BOVIN,Bos taurus (Bovine),exocytosis [GO:0006887]; Golgi ribbon formation [GO:0090161]; microtubule cytoskeleton organization [GO:0000226]; SNARE complex assembly [GO:0035493]; vesicle fusion [GO:0006906] comp83620_c0_seq1,354,62.4294,1.1113946,0,11,,9.00E-33,Q8NNN0,"UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) (Meso-A2pm-adding enzyme) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase) (UDP-MurNAc-tripeptide synthetase) (UDP-N-acetylmuramyl-tripeptide synthetase)","UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) (Meso-A2pm-adding enzyme) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase) (UDP-MurNAc-tripeptide synthetase) (UDP-N-acetylmuramyl-tripeptide synthetase)",GO:0005524; GO:0008765; GO:0007049; GO:0051301; GO:0005737; GO:0009252; GO:0008360,"ATP binding; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity; cell cycle; cell division; cytoplasm; peptidoglycan biosynthetic process; regulation of cell shape",PF01225;PF02875;PF08245;,,,,,,,,,MURE_CORGL,Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025),cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp83633_c0_seq1,440,48.8636,0.54158174,18,0,,,,,,,,,9.00E-13,CHOYP_BRAFLDRAFT_124709.1.1,,,,,,,,, comp8364_c0_seq1,273,36.63,0.33360837,7,2,,2.00E-06,A6QM03,GDP-fucose transporter 1 (Solute carrier family 35 member C1),GDP-fucose transporter 1 (Solute carrier family 35 member C1),GO:0000139; GO:0008643; GO:0016021,Golgi membrane; carbohydrate transport; integral to membrane,PF03151;,,,,,,,,,FUCT1_BOVIN,Bos taurus (Bovine),carbohydrate transport [GO:0008643]; lipid glycosylation [GO:0030259]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp83657_c0_seq2,374,42.7807,0.58603326,8,3,,2.00E-16,Q7Z3F1,Integral membrane protein GPR155 (G-protein coupled receptor PGR22),Integral membrane protein GPR155 (G-protein coupled receptor PGR22),GO:0016021; GO:0035556; GO:0055085,integral to membrane; intracellular signal transduction; transmembrane transport,PF00610;PF03547;,,,,,,,,,GP155_HUMAN,Homo sapiens (Human),cognition [GO:0050890]; intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] comp8365_c0_seq1,245,32.6531,0.48047675,4,0,,3.00E-10,Q9NPF2,Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1),GO:0000139; GO:0001537; GO:0050659; GO:0016051; GO:0005975; GO:0002063; GO:0047756; GO:0030206; GO:0048589; GO:0042733; GO:0048703; GO:0016021; GO:0043066; GO:0030512; GO:0033037; GO:0036342; GO:0009791; GO:0042127; GO:0007585,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; carbohydrate biosynthetic process; carbohydrate metabolic process; chondrocyte development; chondroitin 4-sulfotransferase activity; chondroitin sulfate biosynthetic process; developmental growth; embryonic digit morphogenesis; embryonic viscerocranium morphogenesis; integral to membrane; negative regulation of apoptotic process; negative regulation of transforming growth factor beta receptor signaling pathway; polysaccharide localization; post-anal tail morphogenesis; post-embryonic development; regulation of cell proliferation; respiratory gaseous exchange,PF03567;,,,,,,,,,CHSTB_HUMAN,Homo sapiens (Human),carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585] comp83708_c0_seq1,237,48.9451,0.50257305,7,19,,,,,,,,,4.00E-14,CHOYP_ISCW_ISCW014636.1.2,,,,,,,,, comp83730_c0_seq1,293,44.3686,0.34826276,6,8,,,,,,,,,4.00E-21,CHOYP_LOC100376250.1.1,,,,,,,,, comp83730_c1_seq1,314,37.2611,0.18806161,3,24,,1.00E-17,Q5E9X5,AP-5 complex subunit mu-1 (Adapter-related protein complex 5 subunit mu-1) (Mu5),AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5),GO:0030119; GO:0030131; GO:0005829; GO:0016197; GO:0006886; GO:0005770; GO:0031902; GO:0005765; GO:0005764; GO:0016192,AP-type membrane coat adaptor complex; clathrin adaptor complex; cytosol; endosomal transport; intracellular protein transport; late endosome; late endosome membrane; lysosomal membrane; lysosome; vesicle-mediated transport,PF00928;,,,,,,,,,AP5M1_BOVIN,Bos taurus (Bovine),endosomal transport [GO:0016197]; protein transport [GO:0015031] comp83736_c0_seq1,277,41.5162,1.03155333,6,30,,1.00E-07,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp83745_c0_seq1,234,44.4444,0.63173197,6,0,,2.00E-06,Q7LHG5,Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,,,,,,,,,YI31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp83752_c0_seq1,242,41.3223,0.48620278,3,0,,1.00E-10,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp83755_c0_seq1,583,42.1955,0.58898849,19,28,,2.00E-29,Q2NKY9,Protein jagunal homolog 1,Protein jagunal homolog 1,GO:0005789; GO:0007029; GO:0016021,endoplasmic reticulum membrane; endoplasmic reticulum organization; integral to membrane,PF07086;,,,,,,,,,JAGN1_BOVIN,Bos taurus (Bovine),defense response to fungus [GO:0050832]; endoplasmic reticulum organization [GO:0007029]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; neutrophil differentiation [GO:0030223]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp83758_c0_seq1,209,60.2871,0.95240276,0,0,,9.00E-41,Q6A6R1,DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha),DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha),GO:0003677; GO:0003899; GO:0006351,"DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",PF01000;PF03118;PF01193;,,,,,,,,,RPOA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"transcription, DNA-templated [GO:0006351]" comp83762_c0_seq2,307,48.8599,0.76713143,10,5,,1.00E-31,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,,,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp83764_c0_seq1,361,41.8283,0.19153586,8,8,,9.00E-09,Q5M7Z0,RING finger and transmembrane domain-containing protein 1 (Protein PTD016),RING finger and transmembrane domain-containing protein 1 (Protein PTD016),GO:0016021; GO:0008270,integral to membrane; zinc ion binding,,,,,,,,,,RNFT1_HUMAN,Homo sapiens (Human), comp83789_c0_seq1,250,49.6,0.72127591,8,25,,2.00E-35,Q66H76,Paxillin,Paxillin,GO:0005938; GO:0007160; GO:0005856; GO:0005925; GO:0008270,cell cortex; cell-matrix adhesion; cytoskeleton; focal adhesion; zinc ion binding,PF00412;,6.00E-31,CHOYP_CPIPJ_CPIJ003871.1.1,,,,,,,PAXI_RAT,Rattus norvegicus (Rat),cell-matrix adhesion [GO:0007160]; cellular response to reactive oxygen species [GO:0034614]; growth hormone receptor signaling pathway [GO:0060396]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp83795_c0_seq2,263,38.0228,0.31731228,1,36,,2.00E-29,Q7SXP8,Mannose-1-phosphate guanyltransferase alpha-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-B) (GTP-mannose-1-phosphate guanylyltransferase apha-B),Mannose-1-phosphate guanyltransferase alpha-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-B) (GTP-mannose-1-phosphate guanylyltransferase alpha-b),GO:0009298; GO:0005525; GO:0004475,GDP-mannose biosynthetic process; GTP binding; mannose-1-phosphate guanylyltransferase activity,PF00132;PF00483;,1.00E-33,CHOYP_GMPAA.1.1,,,,,,,GMPAB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),GDP-mannose biosynthetic process [GO:0009298] comp83810_c0_seq1,442,48.8688,0.50345568,18,0,,3.00E-34,Q5U2Q4,Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 15) (ARTD15) (Poly [ADP-ribose] polymerase 16) (PARP-16),Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16),GO:0003950; GO:0005789; GO:0016021; GO:0031965; GO:0006986,NAD+ ADP-ribosyltransferase activity; endoplasmic reticulum membrane; integral to membrane; nuclear membrane; response to unfolded protein,PF00644;,,,,,,,,,PAR16_RAT,Rattus norvegicus (Rat),response to unfolded protein [GO:0006986] comp83857_c0_seq1,642,40.9657,0.52149356,21,4,,4.00E-36,Q4R8W3,Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 3.4.19.12) (EC 6.3.2.-) [Cleaved into: A20p50; A20p37],Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 3.4.19.12) (EC 6.3.2.-) [Cleaved into: A20p50; A20p37],GO:0003677; GO:0006915; GO:0070301; GO:0006954; GO:0005764; GO:0043124; GO:0050728; GO:0045824; GO:0005634; GO:0035871; GO:0071108; GO:0070936; GO:0070536; GO:0006508; GO:0004221; GO:0004842; GO:0004843; GO:0008270,DNA binding; apoptotic process; cellular response to hydrogen peroxide; inflammatory response; lysosome; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of inflammatory response; negative regulation of innate immune response; nucleus; protein K11-linked deubiquitination; protein K48-linked deubiquitination; protein K48-linked ubiquitination; protein K63-linked deubiquitination; proteolysis; ubiquitin thiolesterase activity; ubiquitin-protein ligase activity; ubiquitin-specific protease activity; zinc ion binding,PF02338;PF01754;,,,,,,,,,TNAP3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),apoptotic process [GO:0006915]; cellular response to hydrogen peroxide [GO:0070301]; inflammatory response [GO:0006954]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536] comp83870_c0_seq1,2396,35.0167,0.37724275,114,68,,5.00E-25,Q5QJC4,DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A),DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A),GO:0016787; GO:0005654; GO:0000715,"hydrolase activity; nucleoplasm; nucleotide-excision repair, DNA damage recognition",PF07522;,2.00E-17,CHOYP_DCLRE1A.1.2,,,,,,,DCR1A_CHICK,Gallus gallus (Chicken),"DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protection from non-homologous end joining at telomere [GO:0031848]" comp83919_c0_seq1,339,48.0826,0.78341696,13,30,,4.00E-25,Q502M6,Ankyrin repeat domain-containing protein 29,Ankyrin repeat domain-containing protein 29,,,PF00023;PF12796;,2.00E-44,CHOYP_LOC100369901.1.2,,,,,,,ANR29_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp83920_c0_seq1,498,39.3574,0.4157051,16,10,,2.00E-16,Q9R1S3,GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GO:0006506; GO:0005789; GO:0016021; GO:0016780,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; phosphotransferase activity, for other substituted phosphate groups",PF01663;PF04987;,,,,,,,,,PIGN_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp83926_c0_seq1,490,40.6122,0.79401988,19,32,,1.00E-42,P30337,N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2),N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2),GO:0005096; GO:0048013; GO:0005622; GO:0035556; GO:0046872; GO:0008045; GO:0001565; GO:0050770,GTPase activator activity; ephrin receptor signaling pathway; intracellular; intracellular signal transduction; metal ion binding; motor neuron axon guidance; phorbol ester receptor activity; regulation of axonogenesis,PF00130;PF00620;,3.00E-26,CHOYP_CHIN.1.1,,,,,,,CHIN_RAT,Rattus norvegicus (Rat),ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165] comp83946_c0_seq1,264,44.3182,0.2416448,7,9,,3.00E-36,Q27556,"Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)","Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)",GO:0051287; GO:0005975; GO:0046168; GO:0004367; GO:0009331; GO:0006650,NAD binding; carbohydrate metabolic process; glycerol-3-phosphate catabolic process; glycerol-3-phosphate dehydrogenase [NAD+] activity; glycerol-3-phosphate dehydrogenase complex; glycerophospholipid metabolic process,PF07479;PF01210;,7.00E-30,CHOYP_GPDA.2.2,,,,,,,GPDA_DROAE,Drosophila americana (Fruit fly),carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophospholipid metabolic process [GO:0006650] comp83976_c0_seq1,230,42.6087,0.48838133,3,1,,2.00E-25,A1A535,Ventricular zone-expressed PH domain-containing protein 1 (Protein melted homolog),Ventricular zone-expressed PH domain-containing protein 1 (Protein melted homolog),GO:0005543; GO:0005886,phospholipid binding; plasma membrane,PF00169;,2.00E-37,CHOYP_LOC100167479.1.1,,,,,,,MELT_MOUSE,Mus musculus (Mouse), comp84036_c0_seq1,210,51.4286,0.30197465,2,11,,2.00E-16,O13134,Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4),Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4),GO:0016323; GO:0005452; GO:0016021; GO:0006814; GO:0015293,basolateral plasma membrane; inorganic anion exchanger activity; integral to membrane; sodium ion transport; symporter activity,PF07565;PF00955;,,,,,,,,,S4A4_AMBTI,Ambystoma tigrinum (Eastern tiger salamander),sodium ion transport [GO:0006814] comp84036_c1_seq1,355,41.6901,0.58897526,8,6,,6.00E-30,O18917,Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Anion exchanger 3 brain isoform) (Neuronal band 3-like protein) (Solute carrier family 4 member 3),Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Anion exchanger 3 brain isoform) (Neuronal band 3-like protein) (Solute carrier family 4 member 3),GO:0005452; GO:0016021,inorganic anion exchanger activity; integral to membrane,PF07565;PF00955;,,,,,,,,,B3A3_RABIT,Oryctolagus cuniculus (Rabbit), comp84045_c0_seq1,233,40.7725,0.63415802,5,0,,2.00E-14,Q6ZQW0,"Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1)","Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1)",GO:0005829; GO:0020037; GO:0033754; GO:0046872; GO:0004833; GO:0019441,"cytosol; heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; tryptophan 2,3-dioxygenase activity; tryptophan catabolic process to kynurenine",PF01231;,,,,,,,,,I23O2_HUMAN,Homo sapiens (Human),immune system process [GO:0002376]; tryptophan catabolic process [GO:0006569]; tryptophan catabolic process to kynurenine [GO:0019441] comp84079_c0_seq1,220,38.6364,0.93759513,3,0,,2.00E-13,P10040,Protein crumbs (95F),Protein crumbs (95F),GO:0016324; GO:0016327; GO:0005509; GO:0061336; GO:0046664; GO:0045198; GO:0016332; GO:0016334; GO:0016021; GO:0035002; GO:0035090; GO:0061024; GO:0045746; GO:0046621; GO:0048477; GO:0045494; GO:0008284; GO:0042327; GO:0008104; GO:0035330; GO:0045570; GO:0016028; GO:0042052; GO:0007435; GO:0005918; GO:0030507; GO:0035003; GO:0045186; GO:0045218,"apical plasma membrane; apicolateral plasma membrane; calcium ion binding; cell morphogenesis involved in Malpighian tubule morphogenesis; dorsal closure, amnioserosa morphology change; establishment of epithelial cell apical/basal polarity; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of polarity of follicular epithelium; integral to membrane; liquid clearance, open tracheal system; maintenance of apical/basal cell polarity; membrane organization; negative regulation of Notch signaling pathway; negative regulation of organ growth; oogenesis; photoreceptor cell maintenance; positive regulation of cell proliferation; positive regulation of phosphorylation; protein localization; regulation of hippo signaling cascade; regulation of imaginal disc growth; rhabdomere; rhabdomere development; salivary gland morphogenesis; septate junction; spectrin binding; subapical complex; zonula adherens assembly; zonula adherens maintenance",PF00008;PF07645;PF00054;PF02210;,,,,,,,,,CRB_DROME,Drosophila melanogaster (Fruit fly),"adherens junction organization [GO:0034332]; cell-cell junction assembly [GO:0007043]; cell morphogenesis involved in Malpighian tubule morphogenesis [GO:0061336]; centrosome localization [GO:0051642]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor development [GO:0042051]; dorsal closure, amnioserosa morphology change [GO:0046664]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; liquid clearance, open tracheal system [GO:0035002]; maintenance of apical/basal cell polarity [GO:0035090]; Malpighian tubule morphogenesis [GO:0007443]; membrane organization [GO:0061024]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of organ growth [GO:0046621]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nuclear chromosome segregation [GO:0098813]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphorylation [GO:0042327]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of hippo signaling [GO:0035330]; regulation of imaginal disc growth [GO:0045570]; regulation of intracellular protein transport [GO:0033157]; regulation of protein localization [GO:0032880]; rhabdomere development [GO:0042052]; rhabdomere morphogenesis [GO:0061541]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; tube morphogenesis [GO:0035239]; zonula adherens assembly [GO:0045186]; zonula adherens maintenance [GO:0045218]" comp84083_c0_seq1,607,39.7035,0.68123434,16,13,,4.00E-26,Q07E38,Caveolin-1,Caveolin-1,GO:0000139; GO:0031295; GO:0005901; GO:0005768,Golgi membrane; T cell costimulation; caveola; endosome,PF01146;,5.00E-18,CHOYP_LOC101073024.1.1,5.00E-28,ruditapes_lrc37804,,,,,CAV1_NEONE,Neofelis nebulosa (Clouded leopard),caveola assembly [GO:0070836]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; receptor internalization [GO:0031623]; T cell costimulation [GO:0031295] comp84123_c0_seq1,274,36.8613,1.07844574,0,32,,3.00E-16,Q68DU8,BTB/POZ domain-containing protein KCTD16 (Potassium channel tetramerization domain-containing protein 16),BTB/POZ domain-containing protein KCTD16 (Potassium channel tetramerization domain-containing protein 16),GO:0030054; GO:0045211; GO:0042734; GO:0051260; GO:0043235; GO:0008277,cell junction; postsynaptic membrane; presynaptic membrane; protein homooligomerization; receptor complex; regulation of G-protein coupled receptor protein signaling pathway,PF02214;,3.00E-16,CHOYP_LOC100879129.1.1,,,,,,,KCD16_HUMAN,Homo sapiens (Human),protein homooligomerization [GO:0051260]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] comp84140_c0_seq1,227,39.207,0.34546125,5,17,,1.00E-27,A5A761,Sideroflexin-1,Sideroflexin-1,GO:0008324; GO:0030218; GO:0016021; GO:0055072; GO:0006826; GO:0005743,cation transmembrane transporter activity; erythrocyte differentiation; integral to membrane; iron ion homeostasis; iron ion transport; mitochondrial inner membrane,PF03820;,,,,,,,,,SFXN1_PIG,Sus scrofa (Pig),erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826] comp84158_c0_seq1,605,40.4959,0.28565735,21,54,,2.00E-79,O00628,Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7),GO:0005829; GO:0001958; GO:0008611; GO:0006635; GO:0001764; GO:0005782; GO:0005053; GO:0042803; GO:0016558,cytosol; endochondral ossification; ether lipid biosynthetic process; fatty acid beta-oxidation; neuron migration; peroxisomal matrix; peroxisome matrix targeting signal-2 binding; protein homodimerization activity; protein import into peroxisome matrix,PF00400;,5.00E-43,CHOYP_LOC100370808.1.1,,,,,,,PEX7_HUMAN,Homo sapiens (Human),endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] comp84159_c0_seq1,988,48.1781,0.70819979,38,10,,,,,,,,,9.00E-11,CHOYP_LOC756958.2.2,,,,,,,,, comp84171_c0_seq1,318,46.2264,0.24719346,19,14,,3.00E-47,P26640,Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS),Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS),GO:0005524; GO:0002161; GO:0005829; GO:0005739; GO:0006450; GO:0006418; GO:0006414; GO:0004832; GO:0006438,ATP binding; aminoacyl-tRNA editing activity; cytosol; mitochondrion; regulation of translational fidelity; tRNA aminoacylation for protein translation; translational elongation; valine-tRNA ligase activity; valyl-tRNA aminoacylation,PF08264;PF00043;PF00133;,5.00E-39,CHOYP_LOC101158795.1.1,,,,,,,SYVC_HUMAN,Homo sapiens (Human),tRNA aminoacylation for protein translation [GO:0006418]; valyl-tRNA aminoacylation [GO:0006438] comp8417_c0_seq1,228,64.0351,1.19827886,2,2,,7.00E-28,Q6A7M5,Translation initiation factor IF-2,Translation initiation factor IF-2,GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003743,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation initiation factor activity,PF11987;PF04760;,,,,,,,,,IF2_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp84206_c0_seq1,391,48.3376,0.70806514,8,0,,2.00E-09,Q6P3V7,Tetratricopeptide repeat protein GNN (TPR repeat protein GNN) (Grp94-neighboring nucleotidase),Tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase),GO:0005737,cytoplasm,,,,,,,,,,GNN_RAT,Rattus norvegicus (Rat), comp84212_c0_seq1,298,39.2617,0.96679513,9,0,,2.00E-16,Q80X44,Zinc finger and BTB domain-containing protein 24 (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1) (Zinc finger protein 450),Zinc finger and BTB domain-containing protein 24 (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1) (Zinc finger protein 450),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT24_MOUSE,Mus musculus (Mouse),"hematopoietic progenitor cell differentiation [GO:0002244]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp84214_c0_seq1,599,39.2321,0.39119205,35,35,,2.00E-51,Q5PPX0,Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67),Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67),GO:0003779; GO:0005813; GO:0005737; GO:0045502; GO:0002177; GO:0015631,actin binding; centrosome; cytoplasm; dynein binding; manchette; tubulin binding,PF12799;,6.00E-48,CHOYP_BRAFLDRAFT_124305.1.1,,,,,,,PPR42_XENLA,Xenopus laevis (African clawed frog), comp84225_c1_seq1,277,37.5451,0.93779333,2,30,,2.00E-32,Q5RBC3,Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog),Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog),GO:0000139; GO:0050509; GO:0050508; GO:0015012; GO:0016021; GO:0031227; GO:0006486,Golgi membrane; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; protein glycosylation,PF03016;PF09258;,8.00E-11,CHOYP_EXT1A.1.1,,,,,,,EXT1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486] comp84241_c0_seq1,589,37.691,1.05357447,14,37,,1.00E-16,Q8NCH0,Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1) (hD4ST1),Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1) (hD4ST1),GO:0000139; GO:0001537; GO:0016051; GO:0005975; GO:0030204; GO:0030208; GO:0016021; GO:0042301,Golgi membrane; N-acetylgalactosamine 4-O-sulfotransferase activity; carbohydrate biosynthetic process; carbohydrate metabolic process; chondroitin sulfate metabolic process; dermatan sulfate biosynthetic process; integral to membrane; phosphate ion binding,PF03567;,,,,,,,,,CHSTE_HUMAN,Homo sapiens (Human),carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate proteoglycan metabolic process [GO:0050655] comp84243_c0_seq1,206,63.1068,0.98362974,0,2,,5.00E-40,Q6A7V6,Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS),Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS),GO:0005524; GO:0005737; GO:0000287; GO:0004826; GO:0006432; GO:0000049; GO:0008033,ATP binding; cytoplasm; magnesium ion binding; phenylalanine-tRNA ligase activity; phenylalanyl-tRNA aminoacylation; tRNA binding; tRNA processing,PF03483;PF03484;PF03147;PF01588;,,,,,,,,,SYFB_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033] comp84249_c0_seq1,528,47.5379,0.45112993,4,11,,4.00E-26,Q8CGY6,Protein unc-45 homolog B (Unc-45B),Protein unc-45 homolog B (Unc-45B),GO:0051879; GO:0030154; GO:0061077; GO:0005829; GO:0007517,Hsp90 protein binding; cell differentiation; chaperone-mediated protein folding; cytosol; muscle organ development,PF11701;,,,,,,,,,UN45B_MOUSE,Mus musculus (Mouse),cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517] comp84249_c0_seq2,467,47.7516,0.46753461,0,0,,,,,,,,,1.00E-23,CHOYP_UN45B.1.1,,,,,,,,, comp84276_c0_seq1,281,56.5836,1.38763662,2,4,,2.00E-06,Q49ZI0,Lipid II:glycine glycyltransferase (EC 2.3.2.16) (Factor essential for expression of methicillin resistance X),Lipid II:glycine glycyltransferase (EC 2.3.2.16) (Factor essential for expression of methicillin resistance X),GO:0005737; GO:0009252; GO:0008360; GO:0016755,"cytoplasm; peptidoglycan biosynthetic process; regulation of cell shape; transferase activity, transferring amino-acyl groups",PF02388;,,,,,,,,,FEMX_STAS1,Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229),cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360] comp84292_c0_seq1,634,44.3218,0.68384786,11,33,,8.00E-15,Q17LW0,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp84299_c0_seq1,655,43.9695,0.39346321,15,26,,1.00E-21,O34313,"Trifunctional nucleotide phosphoesterase protein YfkN [Includes: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16); 5'-nucleotidase (EC 3.1.3.5)]","Trifunctional nucleotide phosphoesterase protein YfkN [Includes: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16); 5'-nucleotidase (EC 3.1.3.5)]",GO:0008663; GO:0008254; GO:0008253; GO:0005618; GO:0005576; GO:0046872; GO:0000166; GO:0009166,"2',3'-cyclic-nucleotide 2'-phosphodiesterase activity; 3'-nucleotidase activity; 5'-nucleotidase activity; cell wall; extracellular region; metal ion binding; nucleotide binding; nucleotide catabolic process",PF02872;PF00149;,2.00E-11,CHOYP_LOC591937.1.1,,,,,,,NTPES_BACSU,Bacillus subtilis (strain 168),nucleotide catabolic process [GO:0009166] comp84313_c0_seq1,294,42.8571,0.69412568,0,21,,3.00E-10,P04574,Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit),Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit),GO:0005509; GO:0004198; GO:0005737; GO:0005886,calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoplasm; plasma membrane,PF13833;,,,,,,,,,CPNS1_PIG,Sus scrofa (Pig),proteolysis [GO:0006508] comp84313_c0_seq2,261,41.7625,0.80533969,0,5,,7.00E-06,Q8W4L0,Probable calcium-binding protein CML49 (Calmodulin-like protein 49),Probable calcium-binding protein CML49 (Calmodulin-like protein 49),GO:0005509,calcium ion binding,PF13202;PF13405;,,,,,,,,,CML49_ARATH,Arabidopsis thaliana (Mouse-ear cress),proteolysis [GO:0006508] comp84324_c0_seq1,331,48.3384,0.74025202,4,22,,,,,,,,,9.00E-24,CHOYP_MYO22.2.2,,,,,,,,, comp84368_c1_seq1,233,34.7639,0.85611333,3,10,,1.00E-11,Q9VQU9,Protein bowel (Brother of odd with entrails limited),Protein bowel (Brother of odd with entrails limited),GO:0048617; GO:0048619; GO:0016348; GO:0046331; GO:0046872; GO:0000122; GO:0003676; GO:0005634; GO:0007366; GO:0045944; GO:0000981; GO:0007362; GO:0035220,embryonic foregut morphogenesis; embryonic hindgut morphogenesis; imaginal disc-derived leg joint morphogenesis; lateral inhibition; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleic acid binding; nucleus; periodic partitioning by pair rule gene; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding RNA polymerase II transcription factor activity; terminal region determination; wing disc development,PF00096;PF13912;,,,,,,,,,BOWEL_DROME,Drosophila melanogaster (Fruit fly),"embryonic foregut morphogenesis [GO:0048617]; embryonic hindgut morphogenesis [GO:0048619]; embryonic pattern specification [GO:0009880]; hindgut morphogenesis [GO:0007442]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; lateral inhibition [GO:0046331]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; periodic partitioning by pair rule gene [GO:0007366]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; terminal region determination [GO:0007362]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]" comp84389_c0_seq1,259,37.8378,1.08470536,5,19,,1.00E-23,Q09324,"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)","Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)",GO:0031985; GO:0000139; GO:0003829; GO:0060352; GO:0009101; GO:0016021; GO:0060993; GO:0050901; GO:0006486; GO:0048729,"Golgi cisterna; Golgi membrane; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; cell adhesion molecule production; glycoprotein biosynthetic process; integral to membrane; kidney morphogenesis; leukocyte tethering or rolling; protein glycosylation; tissue morphogenesis",PF02485;,,,,,,,,,GCNT1_MOUSE,Mus musculus (Mouse),cell adhesion molecule production [GO:0060352]; glycoprotein biosynthetic process [GO:0009101]; kidney morphogenesis [GO:0060993]; leukocyte tethering or rolling [GO:0050901]; protein glycosylation [GO:0006486]; response to insulin [GO:0032868]; tissue morphogenesis [GO:0048729] comp84390_c0_seq1,337,37.092,0.78483663,9,27,,3.00E-06,Q80TD3,Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein),Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein),GO:0005737; GO:0008630; GO:0000122; GO:0005634; GO:0005886; GO:0033138; GO:0006468,cytoplasm; intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of transcription from RNA polymerase II promoter; nucleus; plasma membrane; positive regulation of peptidyl-serine phosphorylation; protein phosphorylation,PF14638;PF14637;PF14636;,,,,,,,,,FNIP2_MOUSE,Mus musculus (Mouse),intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] comp84399_c0_seq1,378,46.8254,0.77724205,10,0,,1.00E-21,Q9UHI7,Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3),Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3),GO:0008520; GO:0019852; GO:0016324; GO:0009925; GO:0007420; GO:0005903; GO:0005737; GO:0033300; GO:0005887; GO:0043229; GO:0030324; GO:0015205; GO:0006139; GO:0009636; GO:0070890; GO:0070904,L-ascorbate:sodium symporter activity; L-ascorbic acid metabolic process; apical plasma membrane; basal plasma membrane; brain development; brush border; cytoplasm; dehydroascorbic acid transporter activity; integral to plasma membrane; intracellular organelle; lung development; nucleobase transmembrane transporter activity; nucleobase-containing compound metabolic process; response to toxic substance; sodium-dependent L-ascorbate transmembrane transporter activity; transepithelial L-ascorbic acid transport,PF00860;,5.00E-15,CHOYP_LOC100486632.1.2,,,,,,,S23A1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transport [GO:0015882]; lung development [GO:0030324]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904] comp84415_c0_seq1,827,40.5079,1.15098543,47,0,,4.00E-06,B0BN95,Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease),GO:0005813; GO:0005737; GO:0046872; GO:0004518; GO:0090305; GO:0005634,centrosome; cytoplasm; metal ion binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; nucleus,PF13359;,,,,,,,,,HARB1_RAT,Rattus norvegicus (Rat), comp84416_c1_seq1,712,43.3989,0.57769837,11,9,,3.00E-24,Q8IZD9,Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP),Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP),GO:0005737; GO:0005085; GO:0007264,cytoplasm; guanyl-nucleotide exchange factor activity; small GTPase mediated signal transduction,PF06920;PF14429;PF16172;PF07653;,,,,,,,,,DOCK3_HUMAN,Homo sapiens (Human),small GTPase mediated signal transduction [GO:0007264] comp84430_c1_seq1,229,44.1048,1.17257138,0,7,,1.00E-08,Q6ZR37,Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7),Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,,,,,,,,,PKHG7_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp84467_c0_seq1,390,47.4359,0.38446664,9,3,,1.00E-22,P12080,Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain],Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain],GO:0016324; GO:0007475; GO:0007411; GO:0007414; GO:0009925; GO:0007298; GO:0050839; GO:0007160; GO:0007427; GO:0035099; GO:0007157; GO:0008305; GO:0007229; GO:0016328; GO:0035160; GO:0045185; GO:0007494; GO:0016203; GO:0030239; GO:0004872; GO:0008360; GO:0051492; GO:0007435; GO:0042383; GO:0007608; GO:0007426,"apical plasma membrane; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; axonal defasciculation; basal plasma membrane; border follicle cell migration; cell adhesion molecule binding; cell-matrix adhesion; epithelial cell migration, open tracheal system; hemocyte migration; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; maintenance of protein location; midgut development; muscle attachment; myofibril assembly; receptor activity; regulation of cell shape; regulation of stress fiber assembly; salivary gland morphogenesis; sarcolemma; sensory perception of smell; tracheal outgrowth, open tracheal system",PF01839;PF00357;PF08441;,,,,,,,,,ITA2_DROME,Drosophila melanogaster (Fruit fly),"apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; epithelial cell migration, open tracheal system [GO:0007427]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; maintenance of protein location [GO:0045185]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; myofibril assembly [GO:0030239]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]" comp84470_c0_seq1,388,41.2371,0.18234496,1,23,,,,,,,,,3.00E-30,CHOYP_LOC100372842.1.1,,,,,,,,, comp84517_c0_seq1,255,58.0392,1.07603994,1,3,,5.00E-15,P96921,Exodeoxyribonuclease V gamma chain (EC 3.1.11.5),,GO:0005524; GO:0006281; GO:0005618; GO:0004519; GO:0008854; GO:0009338; GO:0005576; GO:0004386; GO:0090305; GO:0005886,ATP binding; DNA repair; cell wall; endonuclease activity; exodeoxyribonuclease V activity; exodeoxyribonuclease V complex; extracellular region; helicase activity; nucleic acid phosphodiester bond hydrolysis; plasma membrane,,,,,,,,,,EX5C_MYCTU,, comp84518_c0_seq1,215,42.7907,0.53072401,4,6,,1.00E-07,Q9Y2M2,Protein SSUH2 homolog (Protein ssu-2 homolog),Protein SSUH2 homolog (Protein ssu-2 homolog),GO:0005737,cytoplasm,,,,,,,,,,CC032_HUMAN,Homo sapiens (Human), comp84577_c0_seq1,207,52.1739,1.18184576,2,2,,5.00E-11,Q96RW7,Hemicentin-1 (Fibulin-6) (FIBL-6),Hemicentin-1 (Fibulin-6) (FIBL-6),GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896; GO:0007601,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus; visual perception,PF12662;PF07645;PF07474;PF07679;PF00090;,,,,,,,,,HMCN1_HUMAN,Homo sapiens (Human),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp84599_c1_seq1,563,39.254,0.70336105,8,24,,,,,,,,,,,1.00E-35,ruditapes_c16197,,,,,,, comp84606_c0_seq1,323,40.5573,0.23253811,0,0,,2.00E-07,Q58DK1,"Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)","Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)",GO:0004095; GO:0006635; GO:0016021; GO:0005741; GO:0006810,carnitine O-palmitoyltransferase activity; fatty acid beta-oxidation; integral to membrane; mitochondrial outer membrane; transport,PF00755;PF16484;,,,,,,,,,CPT1B_BOVIN,Bos taurus (Bovine),fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810] comp84606_c0_seq2,431,41.7633,0.27235048,10,3,,1.00E-57,Q5U3U3,"Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)","Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)",GO:0004095; GO:0006635; GO:0005743; GO:0006810,carnitine O-palmitoyltransferase activity; fatty acid beta-oxidation; mitochondrial inner membrane; transport,PF00755;,2.00E-27,CHOYP_CPT2.1.1,,,,,,,CPT2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810] comp84635_c0_seq1,263,47.5285,0.20381149,6,7,,2.00E-29,Q5ZLN0,Leucine-rich repeat-containing protein 40,Leucine-rich repeat-containing protein 40,,,PF13855;,2.00E-12,CHOYP_LRC40.1.2,,,,,,,LRC40_CHICK,Gallus gallus (Chicken), comp84640_c0_seq1,426,50.2347,0.44759156,8,26,,7.00E-14,Q1RMI3,GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2),GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2),GO:0005634; GO:0045944; GO:0044212; GO:0006351,"nucleus; positive regulation of transcription from RNA polymerase II promoter; transcription regulatory region DNA binding; transcription, DNA-dependent",PF12796;,,,,,,,,,GABP1_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp84640_c1_seq1,279,47.6703,0.57065951,11,0,,2.00E-15,Q18297,Transient receptor potential cation channel subfamily A member 1 homolog,Transient receptor potential cation channel subfamily A member 1 homolog,GO:0016021; GO:0005216; GO:0043025; GO:0031513; GO:0050896,integral to membrane; ion channel activity; neuronal cell body; nonmotile primary cilium; response to stimulus,PF12796;PF00520;,1.00E-39,CHOYP_LOC593338.1.2,,,,,,,TRPA1_CAEEL,Caenorhabditis elegans,response to stimulus [GO:0050896] comp84643_c0_seq1,238,57.9832,0.94240437,0,6,,6.00E-25,P0AAE0,D-serine/D-alanine/glycine transporter,D-serine/D-alanine/glycine transporter,GO:0042944; GO:0042945; GO:0015180; GO:0042895; GO:0001761; GO:0015187; GO:0016021; GO:0005886,D-alanine transmembrane transporter activity; D-serine transmembrane transporter activity; L-alanine transmembrane transporter activity; antibiotic transporter activity; beta-alanine transmembrane transporter activity; glycine transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,CYCA_ECOLI,Escherichia coli (strain K12),antibiotic transport [GO:0042891]; beta-alanine transport [GO:0001762]; D-alanine transport [GO:0042941]; D-serine transport [GO:0042942]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808] comp84708_c0_seq1,403,45.9057,0.52196704,13,0,,2.00E-42,A6H5Z3,Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2),Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2),GO:0000145; GO:0006904,exocyst; vesicle docking involved in exocytosis,PF04091;,3.00E-25,CHOYP_EXC6B.1.1,,,,,,,EXC6B_MOUSE,Mus musculus (Mouse),vesicle docking involved in exocytosis [GO:0006904] comp84722_c0_seq1,529,41.2098,0.58703456,4,28,,3.00E-63,O55055,tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog MmuIIP) (DNA MTase homolog MmuIIP) (M.MmuIIP) (Met-2),tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog MmuIIP) (DNA MTase homolog MmuIIP) (M.MmuIIP) (Met-2),GO:0003677; GO:0006306; GO:0003723; GO:0008168; GO:0005634; GO:0001975; GO:0008033,DNA binding; DNA methylation; RNA binding; methyltransferase activity; nucleus; response to amphetamine; tRNA processing,PF00145;,4.00E-24,CHOYP_TRDMT1.1.1,,,,,,,TRDMT_MOUSE,Mus musculus (Mouse),response to amphetamine [GO:0001975]; tRNA methylation [GO:0030488] comp84728_c1_seq1,465,44.3011,0.79065311,8,32,,3.00E-19,Q9QUH6,Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) (p135 SynGAP),Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) (p135 SynGAP),GO:0005099; GO:0030054; GO:0005737; GO:0031235; GO:0046580; GO:0005543; GO:0014069; GO:0048167; GO:0007165,Ras GTPase activator activity; cell junction; cytoplasm; intrinsic to internal side of plasma membrane; negative regulation of Ras protein signal transduction; phospholipid binding; postsynaptic density; regulation of synaptic plasticity; signal transduction,PF00168;PF12004;PF00616;,1.00E-11,CHOYP_NGAP.2.2,,,,,,,SYGP1_RAT,Rattus norvegicus (Rat),negative regulation of Ras protein signal transduction [GO:0046580]; regulation of synaptic plasticity [GO:0048167]; signal transduction [GO:0007165] comp84732_c0_seq1,296,40.5405,0.35880808,6,25,,3.00E-35,Q9Y4E8,Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4),Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4),GO:0030509; GO:0004197; GO:0005737; GO:0035520; GO:0030512; GO:0005634; GO:0060389; GO:0007179; GO:0004221; GO:0006511; GO:0004843,BMP signaling pathway; cysteine-type endopeptidase activity; cytoplasm; monoubiquitinated protein deubiquitination; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; pathway-restricted SMAD protein phosphorylation; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;PF14533;,,,,,,,,,UBP15_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp84733_c0_seq2,401,61.596,1.1074449,0,33,,4.00E-19,P60119,Putative replication protein,Putative replication protein,GO:0006276,plasmid maintenance,PF10134;,,,,,,,,,REPX_WIGBR,Wigglesworthia glossinidia brevipalpis,plasmid maintenance [GO:0006276] comp84734_c0_seq1,586,36.6894,0.30829922,21,44,,1.00E-17,Q9NZJ4,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0030424; GO:0070852; GO:0008219; GO:0051087; GO:0030425; GO:0005739; GO:0090084; GO:0005634; GO:0006457,ATP binding; axon; cell body fiber; cell death; chaperone binding; dendrite; mitochondrion; negative regulation of inclusion body assembly; nucleus; protein folding,PF05168;PF00240;,,,,,,,,,SACS_HUMAN,Homo sapiens (Human),negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] comp84746_c1_seq1,218,45.8716,0.2680595,7,0,,4.00E-07,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp84772_c0_seq1,258,61.6279,0.94347315,0,5,,4.00E-19,P63629,Homoserine dehydrogenase (HDH) (EC 1.1.1.3),,GO:0050661; GO:0016597; GO:0005618; GO:0040007; GO:0004412; GO:0009097; GO:0009086; GO:0005886; GO:0009088,NADP binding; amino acid binding; cell wall; growth; homoserine dehydrogenase activity; isoleucine biosynthetic process; methionine biosynthetic process; plasma membrane; threonine biosynthetic process,,,,,,,,,,DHOM_MYCTU,, comp84786_c0_seq1,721,43.5506,0.5565348,26,0,,5.00E-16,Q9NYQ7,Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;,,,,,,,,,CELR3_HUMAN,Homo sapiens (Human),"axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp84789_c0_seq1,405,42.2222,0.51076632,4,22,,3.00E-14,P68907,E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3),GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,PF00595;,1.00E-35,CHOYP_PDZRN3.1.1,,,,,,,PZRN3_RAT,Rattus norvegicus (Rat),neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] comp84840_c0_seq1,236,43.6441,0.80613692,9,0,,3.00E-07,Q91VN0,Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3),GO:0044332; GO:0042813; GO:0060612; GO:0060033; GO:0009952; GO:1902262; GO:0048539; GO:0060349; GO:0046849; GO:0060444; GO:0060070; GO:0042074; GO:0060764; GO:0042632; GO:0008203; GO:0015026; GO:0048596; GO:0042733; GO:0060059; GO:0006897; GO:0005783; GO:0035426; GO:0001702; GO:0016021; GO:0005739; GO:0002076; GO:0005886; GO:0033690; GO:0051091; GO:0045944; GO:0043235; GO:0042981; GO:0046850; GO:0045598; GO:0061178; GO:0030278; GO:0061304; GO:0035019,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt-activated receptor activity; adipose tissue development; anatomical structure regression; anterior/posterior pattern specification; apoptotic process involved in patterning of blood vessels; bone marrow development; bone morphogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; cell migration involved in gastrulation; cell-cell signaling involved in mammary gland development; cholesterol homeostasis; cholesterol metabolic process; coreceptor activity; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic retina morphogenesis in camera-type eye; endocytosis; endoplasmic reticulum; extracellular matrix-cell signaling; gastrulation with mouth forming second; integral to membrane; mitochondrion; osteoblast development; plasma membrane; positive regulation of osteoblast proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; receptor complex; regulation of apoptotic process; regulation of bone remodeling; regulation of fat cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of ossification; retinal blood vessel morphogenesis; somatic stem cell maintenance,PF00057;PF00058;,,,,,,,,,LRP5_MOUSE,Mus musculus (Mouse),"adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]" comp84840_c1_seq1,204,47.549,0.36575366,3,0,,2.00E-18,Q6NY73,Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B),Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B),GO:0007155; GO:0016020; GO:0005578; GO:0005044,cell adhesion; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00651;PF00530;,,,,,,,,,L3BPB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155] comp84840_c2_seq1,241,53.112,0.59140803,8,0,,2.00E-07,Q61003,T-cell differentiation antigen CD6 (CD antigen CD6),T-cell differentiation antigen CD6 (CD antigen CD6),GO:0007155; GO:0009986; GO:0016021; GO:0005044,cell adhesion; cell surface; integral to membrane; scavenger receptor activity,PF00530;,,,,,,,,,CD6_MOUSE,Mus musculus (Mouse),acute inflammatory response to antigenic stimulus [GO:0002438]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immunological synapse formation [GO:0001771]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of T cell proliferation [GO:0042102]; response to lipopolysaccharide [GO:0032496] comp84842_c0_seq1,249,50.6024,0.84002389,0,10,,4.00E-07,Q9VN14,Contactin,Contactin,GO:0031225; GO:0008366; GO:0030246; GO:0061343; GO:0060857; GO:0045197; GO:0021682; GO:0005886; GO:0005918; GO:0019991,anchored to membrane; axon ensheathment; carbohydrate binding; cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; establishment or maintenance of epithelial cell apical/basal polarity; nerve maturation; plasma membrane; septate junction; septate junction assembly,PF00041;PF00047;PF00059;,,,,,,,,,CONT_DROME,Drosophila melanogaster (Fruit fly),axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991] comp84868_c1_seq1,440,42.9545,0.79014966,7,0,,8.00E-19,Q5XX13,F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor),F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor),,,PF00400;,,,,,,,,,FBW10_HUMAN,Homo sapiens (Human), comp84875_c0_seq1,405,42.2222,0.45401451,1,45,,8.00E-42,A2RT91,Ankyrin and armadillo repeat-containing protein,Ankyrin and armadillo repeat-containing protein,GO:0016021,integral to membrane,PF00514;,3.00E-12,CHOYP_BRAFLDRAFT_75707.1.1,,,,,,,ANKAR_MOUSE,Mus musculus (Mouse), comp84884_c0_seq1,257,73.5409,1.09862712,0,3,,6.00E-07,Q9KPQ4,Membrane-bound lytic murein transglycosylase A (EC 4.2.2.n1) (Murein hydrolase A),Membrane-bound lytic murein transglycosylase A (EC 4.2.2.n1) (Murein hydrolase A),GO:0016837; GO:0003824; GO:0009279; GO:0004553; GO:0009253; GO:0009254,"carbon-oxygen lyase activity, acting on polysaccharides; catalytic activity; cell outer membrane; hydrolase activity, hydrolyzing O-glycosyl compounds; peptidoglycan catabolic process; peptidoglycan turnover",PF06725;PF03562;,,,,,,,,,MLTA_VIBCH,Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961),cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254] comp84903_c0_seq1,274,41.2409,0.881422,2,0,,2.00E-11,Q767I8,Protocadherin alpha-4 (PCDH-alpha-4) (Cadherin-related neuronal receptor 4),Protocadherin alpha-4 (PCDH-alpha-4) (Cadherin-related neuronal receptor 4),GO:0005509; GO:0007156; GO:0016021; GO:0042476; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; odontogenesis; plasma membrane,PF00028;PF08266;PF15974;,,,,,,,,,PCDA4_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; odontogenesis [GO:0042476] comp84907_c0_seq1,354,50.2825,0.89635862,4,8,,5.00E-29,P22534,"Endoglucanase A (EC 3.2.1.4) (Cellulase A) (Endo-1,4-beta-glucanase A)","Endoglucanase A (EC 3.2.1.4) (Cellulase A) (Endo-1,4-beta-glucanase A)",GO:0008810; GO:0030248; GO:0030245,cellulase activity; cellulose binding; cellulose catabolic process,PF00942;PF02011;PF00759;,,,6.00E-37,ruditapes_c6979,,,,,GUNA_CALSA,Caldicellulosiruptor saccharolyticus (Caldocellum saccharolyticum),cellulose catabolic process [GO:0030245] comp84907_c0_seq2,275,51.6364,0.7666768,3,0,,,,,,,,,6.00E-12,CHOYP_NEMVEDRAFT_V1G83869.3.3,1.00E-13,ruditapes_c17736,,,,,,, comp84909_c0_seq1,244,58.1967,0.97514076,0,10,,1.00E-10,Q9KHT9,Carnitine transport ATP-binding protein OpuCA (EC 3.6.3.32),Carnitine transport ATP-binding protein OpuCA (EC 3.6.3.32),GO:0005524; GO:0006200; GO:0031460; GO:0016020; GO:0015418; GO:0006950,ATP binding; ATP catabolic process; glycine betaine transport; membrane; quaternary-ammonium-compound-transporting ATPase activity; response to stress,PF00005;PF00571;,,,,,,,,,OPUCA_LISMN,Listeria monocytogenes,glycine betaine transport [GO:0031460] comp84913_c0_seq1,550,36.3636,1.10598519,4,34,,2.00E-40,Q9VUL9,"Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)","Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)",GO:0033932; GO:0032580; GO:0005797; GO:0036071; GO:0018392; GO:0016021; GO:0007399; GO:0006486,"1,3-alpha-L-fucosidase activity; Golgi cisterna membrane; Golgi medial cisterna; N-glycan fucosylation; glycoprotein 3-alpha-L-fucosyltransferase activity; integral to membrane; nervous system development; protein glycosylation",PF17039;PF00852;,7.00E-15,CHOYP_DANA_GF23688.1.1,,,,,,,FUCTA_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] comp84916_c0_seq1,361,38.7812,0.54565449,5,37,,1.00E-16,Q7ZYY4,Protein FAM3C,Protein FAM3C,GO:0005576; GO:0007275,extracellular region; multicellular organismal development,,,,,,,,,,FAM3C_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),multicellular organism development [GO:0007275] comp84916_c1_seq1,214,35.0467,0.16337743,1,12,,,,,,,,,,,5.00E-16,ruditapes_c27786,,,,,,, comp84933_c0_seq1,564,42.7305,0.39334571,15,22,,3.00E-23,Q53HC5,Kelch-like protein 26,Kelch-like protein 26,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH26_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp84975_c0_seq1,337,47.181,0.43403271,3,8,,5.00E-29,Q95000,Cholinesterase 1 (EC 3.1.1.8) (Fragment),Cholinesterase 1 (EC 3.1.1.8) (Fragment),GO:0004091; GO:0004104,carboxylesterase activity; cholinesterase activity,PF00135;,,,,,,,,,CHLE1_BRALA,Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum), comp84983_c1_seq1,233,39.9142,0.97955293,5,0,,2.00E-12,P85977,Zinc finger protein (Fragment),Zinc finger protein (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNFP_CHLAE,Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp84984_c0_seq1,250,44,1.33158629,0,21,,3.00E-21,Q5NA18,Metal tolerance protein 5 (OsMTP5),Metal tolerance protein 5 (OsMTP5),GO:0008324; GO:0016021; GO:0005774,cation transmembrane transporter activity; integral to membrane; vacuolar membrane,PF01545;PF16916;,,,,,,,,,MTP5_ORYSJ,Oryza sativa subsp. japonica (Rice),regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp85007_c0_seq1,260,46.1538,0.79773339,2,24,,2.00E-15,Q9WTW7,Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1),Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1),GO:0008520; GO:0016324; GO:0009925; GO:0007420; GO:0005903; GO:0005737; GO:0033300; GO:0005887; GO:0043229; GO:0030324; GO:0009636; GO:0070890; GO:0070904,L-ascorbate:sodium symporter activity; apical plasma membrane; basal plasma membrane; brain development; brush border; cytoplasm; dehydroascorbic acid transporter activity; integral to plasma membrane; intracellular organelle; lung development; response to toxic substance; sodium-dependent L-ascorbate transmembrane transporter activity; transepithelial L-ascorbic acid transport,PF00860;,,,,,,,,,S23A1_RAT,Rattus norvegicus (Rat),brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904] comp85014_c1_seq1,378,43.1217,0.35060375,15,2,,2.00E-42,A2ACP1,Tetratricopeptide repeat protein 39A (TPR repeat protein 39A),Tetratricopeptide repeat protein 39A (TPR repeat protein 39A),,,PF10300;,9.00E-50,CHOYP_BRAFLDRAFT_205333.1.1,,,,,,,TT39A_MOUSE,Mus musculus (Mouse), comp85027_c0_seq1,358,42.4581,0.44438897,6,12,,2.00E-13,O29548,"Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase)","Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase)",GO:0005524; GO:0006094; GO:0046872; GO:0006090; GO:0008986,"ATP binding; gluconeogenesis; metal ion binding; pyruvate metabolic process; pyruvate, water dikinase activity",PF00391;PF02896;PF01326;,,,,,,,,,PPSA_ARCFU,Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126),gluconeogenesis [GO:0006094]; pyruvate metabolic process [GO:0006090] comp85042_c0_seq1,330,36.0606,0.37721144,13,7,,2.00E-10,Q8AW42,Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13),Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13),GO:0000139; GO:0016021; GO:0046873; GO:0006829,Golgi membrane; integral to membrane; metal ion transmembrane transporter activity; zinc ion transport,PF02535;,,,,,,,,,S39AD_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cellular zinc ion homeostasis [GO:0006882]; zinc II ion transmembrane transport [GO:0071577]; zinc II ion transport [GO:0006829] comp85056_c0_seq1,489,39.2638,0.9074112,3,30,,4.00E-22,Q866F1,"Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)","Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)",GO:0032580; GO:0008107; GO:0016021; GO:0006486,Golgi cisterna membrane; galactoside 2-alpha-L-fucosyltransferase activity; integral to membrane; protein glycosylation,PF01531;,,,,,,,,,FUT1_SAISC,Saimiri sciureus (Common squirrel monkey),protein glycosylation [GO:0006486] comp85065_c0_seq1,621,43.3172,0.48491049,22,10,,9.00E-40,Q9UHC1,DNA mismatch repair protein Mlh3 (MutL protein homolog 3),DNA mismatch repair protein Mlh3 (MutL protein homolog 3),GO:0005524; GO:0016887; GO:0032390; GO:0032407; GO:0019237; GO:0005712; GO:0003682; GO:0007144; GO:0001673; GO:0007140; GO:0006298; GO:0030983; GO:0008104; GO:0007131; GO:0003696; GO:0003697; GO:0000795; GO:0007130,ATP binding; ATPase activity; MutLbeta complex; MutSalpha complex binding; centromeric DNA binding; chiasma; chromatin binding; female meiosis I; male germ cell nucleus; male meiosis; mismatch repair; mismatched DNA binding; protein localization; reciprocal meiotic recombination; satellite DNA binding; single-stranded DNA binding; synaptonemal complex; synaptonemal complex assembly,PF01119;PF08676;,,,,,,,,,MLH3_HUMAN,Homo sapiens (Human),female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] comp85073_c0_seq1,587,44.4634,0.62925272,1,73,,1.00E-10,Q51330,Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein),Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein),GO:0015297; GO:0016021; GO:0006811; GO:0005886,antiporter activity; integral to membrane; ion transport; plasma membrane,PF07690;,,,,,,,,,OXLT_OXAFO,Oxalobacter formigenes,ion transport [GO:0006811] comp85137_c0_seq1,246,44.3089,1.164329,0,23,,1.00E-18,A9C3R9,All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b),All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b),GO:0005737; GO:0016787; GO:0046872; GO:0005886,cytoplasm; hydrolase activity; metal ion binding; plasma membrane,PF03055;,,,,,,,,,RP65B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp85162_c0_seq1,573,41.8848,1.05515027,18,33,,8.00E-32,Q495T6,"Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]","Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]",GO:0005794; GO:0005783; GO:0005615; GO:0016021; GO:0004222; GO:0006508; GO:0008270,Golgi apparatus; endoplasmic reticulum; extracellular space; integral to membrane; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01431;PF05649;,,,,,,,,,MMEL1_HUMAN,Homo sapiens (Human), comp85168_c0_seq1,289,61.5917,1.03572669,0,20,,2.00E-20,P64678,Uncharacterized protein Mb0050,Uncharacterized protein Mb0050,,,,,,,,,,,,Y050_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp85194_c0_seq1,533,40.5253,0.32677797,21,23,,,,,,,,,9.00E-71,CHOYP_BRAFLDRAFT_280343.1.1,,,,,,,,, comp85194_c1_seq1,513,39.1813,0.51565204,24,12,,1.00E-67,Q8MJJ1,Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog),Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog),GO:0042609; GO:0005829; GO:0005634; GO:0030140,CD4 receptor binding; cytosol; nucleus; trans-Golgi network transport vesicle,PF00561;,,,,,,,,,SPG21_BOVIN,Bos taurus (Bovine), comp85219_c0_seq1,310,44.5161,0.60954467,0,0,,5.00E-17,Q62739,Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein),Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein),GO:0017112; GO:0005856; GO:0005829; GO:0030027; GO:0005634; GO:0015031,Rab guanyl-nucleotide exchange factor activity; cytoskeleton; cytosol; lamellipodium; nucleus; protein transport,PF06428;,4.00E-21,CHOYP_ISCW_ISCW014818.1.1,,,,,,,RAB3I_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp85244_c0_seq1,369,49.8645,0.96583529,1,21,,3.00E-18,P34308,Calpain clp-1 (EC 3.4.22.-),Calpain clp-1 (EC 3.4.22.-),GO:0031430; GO:0004198; GO:0010940; GO:0006508,M band; calcium-dependent cysteine-type endopeptidase activity; positive regulation of necrotic cell death; proteolysis,PF01067;PF00648;,9.00E-18,CHOYP_LOC100882339.1.2,,,,,,,CAN_CAEEL,Caenorhabditis elegans,positive regulation of necrotic cell death [GO:0010940]; proteolysis [GO:0006508] comp85261_c0_seq1,412,44.9029,0.14481151,8,12,,3.00E-07,Q6ZT07,TBC1 domain family member 9 (TBC1 domain family member 9A),TBC1 domain family member 9 (TBC1 domain family member 9A),GO:0005097; GO:0005509; GO:0032851,Rab GTPase activator activity; calcium ion binding; positive regulation of Rab GTPase activity,PF02893;PF00566;,,,,,,,,,TBCD9_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp85270_c0_seq1,657,36.6819,0.54719461,7,30,,6.00E-11,D3YXK1,Atherin (Sterile alpha motif domain-containing protein 1) (SAM domain-containing protein 1),Atherin (Sterile alpha motif domain-containing protein 1) (SAM domain-containing protein 1),GO:0005737; GO:0005576,cytoplasm; extracellular region,PF00536;,,,,,,,,,SAMD1_MOUSE,Mus musculus (Mouse), comp85282_c0_seq1,381,50.6562,1.03782502,12,10,,6.00E-19,Q5G265,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,1.00E-13,ruditapes2_lrc4264,,,,,NETR_SAGLB,Saguinus labiatus (Red-chested mustached tamarin),exocytosis [GO:0006887] comp85314_c0_seq1,312,43.9103,0.27006317,10,7,,5.00E-19,E1BB03,DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)],GO:0005524; GO:0003677; GO:0006281; GO:0036292; GO:0070530; GO:0036310; GO:0004520; GO:0004386; GO:0045910; GO:0043596; GO:0031297; GO:0048478; GO:0009411; GO:0008270,ATP binding; DNA binding; DNA repair; DNA rewinding; K63-linked polyubiquitin binding; annealing helicase activity; endodeoxyribonuclease activity; helicase activity; negative regulation of DNA recombination; nuclear replication fork; replication fork processing; replication fork protection; response to UV; zinc ion binding,PF00271;PF01844;PF00176;,,,,,,,,,ZRAB3_BOVIN,Bos taurus (Bovine),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411] comp85317_c1_seq1,379,45.1187,0.74930099,4,5,,4.00E-19,P16546,"Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)","Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)",GO:0030018; GO:0051693; GO:0005509; GO:0032437; GO:0005916; GO:0016328; GO:0033270; GO:0046982; GO:0030507,Z disc; actin filament capping; calcium ion binding; cuticular plate; fascia adherens; lateral plasma membrane; paranode region of axon; protein heterodimerization activity; spectrin binding,PF13499;PF08726;PF00018;PF00435;,2.00E-33,CHOYP_LOC100377364.2.2,,,,,,,SPTN1_MOUSE,Mus musculus (Mouse),actin filament capping [GO:0051693] comp85317_c2_seq1,222,45.4955,0.71533127,4,11,,4.00E-07,Q00963,Spectrin beta chain,Spectrin beta chain,GO:0003779; GO:0051693; GO:0030506; GO:0016327; GO:0030424; GO:0016199; GO:0045169; GO:0045478; GO:0016328; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0005546; GO:0072499; GO:0007009; GO:0008091; GO:0045170; GO:0030721; GO:0005200,"actin binding; actin filament capping; ankyrin binding; apicolateral plasma membrane; axon; axon midline choice point recognition; fusome; fusome organization; lateral plasma membrane; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; phosphatidylinositol-4,5-bisphosphate binding; photoreceptor cell axon guidance; plasma membrane organization; spectrin; spectrosome; spectrosome organization; structural constituent of cytoskeleton",PF00307;PF00435;,,,,,,,,,SPTCB_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721] comp85326_c1_seq1,254,36.6142,0.47222954,7,21,,6.00E-26,Q8TF20,Zinc finger protein 721,Zinc finger protein 721,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN721_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp85329_c0_seq1,239,50.2092,0.93360901,1,0,,2.00E-10,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp85360_c0_seq1,554,46.9314,0.40681826,27,0,,9.00E-27,O70244,Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor),GO:0031526; GO:0005509; GO:0008203; GO:0031419; GO:0030666; GO:0010008; GO:0030492; GO:0020028; GO:0042802; GO:0001701; GO:0043202; GO:0005765; GO:0043234; GO:0070207; GO:0004872; GO:0006898; GO:0007584; GO:0006766,brush border membrane; calcium ion binding; cholesterol metabolic process; cobalamin binding; endocytic vesicle membrane; endosome membrane; hemoglobin binding; hemoglobin import; identical protein binding; in utero embryonic development; lysosomal lumen; lysosomal membrane; protein complex; protein homotrimerization; receptor activity; receptor-mediated endocytosis; response to nutrient; vitamin metabolic process,PF00431;PF00008;PF12947;PF07645;,4.00E-31,CHOYP_LOC100705265.3.3,,,,,,,CUBN_RAT,Rattus norvegicus (Rat),cholesterol metabolic process [GO:0008203]; cobalamin transport [GO:0015889]; hemoglobin import [GO:0020028]; in utero embryonic development [GO:0001701]; protein homotrimerization [GO:0070207]; receptor-mediated endocytosis [GO:0006898]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] comp85383_c0_seq1,331,51.0574,0.44464692,6,14,,5.00E-08,Q9Y226,Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3),Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3),GO:0005887; GO:0015101,integral to plasma membrane; organic cation transmembrane transporter activity,PF00083;,4.00E-22,CHOYP_DWIL_GK11734.1.1,,,,,,,S22AD_HUMAN,Homo sapiens (Human),nicotinate transport [GO:2001142]; organic cation transport [GO:0015695]; urate transport [GO:0015747] comp85398_c0_seq1,214,36.9159,0.46807989,4,0,,6.00E-43,O35963,Ras-related protein Rab-33B,Ras-related protein Rab-33B,GO:0005525; GO:0005796; GO:0000139; GO:0006914; GO:0015031; GO:2000785; GO:2000156; GO:0007264,"GTP binding; Golgi lumen; Golgi membrane; autophagy; protein transport; regulation of autophagic vacuole assembly; regulation of retrograde vesicle-mediated transport, Golgi to ER; small GTPase mediated signal transduction",PF00071;,6.00E-11,CHOYP_RAB8A.2.3,,,,,,,RB33B_MOUSE,Mus musculus (Mouse),"autophagy [GO:0006914]; intra-Golgi vesicle-mediated transport [GO:0006891]; negative regulation of constitutive secretory pathway [GO:1903434]; protein targeting to Golgi [GO:0000042]; regulation of autophagosome assembly [GO:2000785]; regulation of Golgi organization [GO:1903358]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; skeletal system morphogenesis [GO:0048705]; small GTPase mediated signal transduction [GO:0007264]" comp85398_c1_seq1,516,41.8605,0.4589861,9,57,,2.00E-52,O35963,Ras-related protein Rab-33B,Ras-related protein Rab-33B,GO:0005525; GO:0005796; GO:0000139; GO:0006914; GO:0015031; GO:2000785; GO:2000156; GO:0007264,"GTP binding; Golgi lumen; Golgi membrane; autophagy; protein transport; regulation of autophagic vacuole assembly; regulation of retrograde vesicle-mediated transport, Golgi to ER; small GTPase mediated signal transduction",PF00071;,6.00E-85,CHOYP_LOC100367291.1.1,,,,,,,RB33B_MOUSE,Mus musculus (Mouse),"autophagy [GO:0006914]; intra-Golgi vesicle-mediated transport [GO:0006891]; negative regulation of constitutive secretory pathway [GO:1903434]; protein targeting to Golgi [GO:0000042]; regulation of autophagosome assembly [GO:2000785]; regulation of Golgi organization [GO:1903358]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; skeletal system morphogenesis [GO:0048705]; small GTPase mediated signal transduction [GO:0007264]" comp85482_c0_seq1,474,40.7173,0.25871575,4,7,,8.00E-28,Q6IND4,Endonuclease/exonuclease/phosphatase family domain-containing protein 1,Endonuclease/exonuclease/phosphatase family domain-containing protein 1,GO:0003677; GO:0006281,DNA binding; DNA repair,PF03372;,2.00E-28,CHOYP_EEPD1.1.1,,,,,,,EEPD1_XENLA,Xenopus laevis (African clawed frog),DNA repair [GO:0006281] comp85496_c0_seq1,635,44.8819,0.37876024,19,32,,6.00E-64,Q8K370,Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),GO:0003995; GO:0050660; GO:0016787; GO:0005739; GO:0016772,"acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; hydrolase activity; mitochondrion; transferase activity, transferring phosphorus-containing groups",PF00441;PF02770;PF02771;PF01636;PF13419;,1.00E-13,CHOYP_LOC100375888.1.1,,,,,,,ACD10_MOUSE,Mus musculus (Mouse),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp85500_c0_seq1,610,42.2951,0.45379834,27,38,,1.00E-55,P55017,Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter),Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter),GO:0016324; GO:0005829; GO:0005887; GO:0035725; GO:0015378,apical plasma membrane; cytosol; integral to plasma membrane; sodium ion transmembrane transport; sodium:chloride symporter activity,PF00324;PF08403;PF03522;,6.00E-74,CHOYP_S12A2.1.2,,,,,,,S12A3_HUMAN,Homo sapiens (Human),ion transport [GO:0006811]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transport [GO:0006810] comp8550_c0_seq1,240,61.25,1.1612507,0,7,,4.00E-20,Q8FTQ2,Translation initiation factor IF-3,Translation initiation factor IF-3,GO:0005737; GO:0003743,cytoplasm; translation initiation factor activity,PF00707;PF05198;,,,,,,,,,IF3_COREF,Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395), comp85517_c0_seq1,274,41.6058,0.17118186,13,0,,1.00E-06,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp85544_c0_seq1,376,44.1489,0.60514072,10,0,,4.00E-36,Q9JLB4,Cubilin (Intrinsic factor-cobalamin receptor),Cubilin (Intrinsic factor-cobalamin receptor),GO:0005794; GO:0016324; GO:0005903; GO:0005509; GO:0008203; GO:0005905; GO:0031419; GO:0030139; GO:0005783; GO:0005768; GO:0010008; GO:0042953; GO:0005765; GO:0004872; GO:0006898,Golgi apparatus; apical plasma membrane; brush border; calcium ion binding; cholesterol metabolic process; coated pit; cobalamin binding; endocytic vesicle; endoplasmic reticulum; endosome; endosome membrane; lipoprotein transport; lysosomal membrane; receptor activity; receptor-mediated endocytosis,PF00431;PF00008;PF12947;PF07645;,8.00E-19,CHOYP_LOC591417.2.2,,,,,,,CUBN_MOUSE,Mus musculus (Mouse),cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898] comp85572_c0_seq1,375,60.5333,1.05093915,0,30,,5.00E-55,Q6A7J8,Elongation factor Ts (EF-Ts),Elongation factor Ts (EF-Ts),GO:0005737; GO:0003746,cytoplasm; translation elongation factor activity,PF00889;,,,,,,,,,EFTS_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp8557_c0_seq1,215,35.3488,0.4566695,2,2,,6.00E-15,A6MVL7,Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit),GO:0009055; GO:0016021; GO:0046872; GO:0005743; GO:0016491; GO:0070469; GO:0022904,electron carrier activity; integral to membrane; metal ion binding; mitochondrial inner membrane; oxidoreductase activity; respiratory chain; respiratory electron transport chain,PF00032;PF00033;,3.00E-27,CHOYP_COX2.2.2,,,,,,,CYB_MYZSE,Myzostoma seymourcollegiorum (Polychaete worm),"mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]" comp85580_c1_seq1,509,43.8114,0.45169256,12,20,,1.00E-13,Q2TBA3,Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase),Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase),GO:0001923; GO:0042098; GO:0050852; GO:0007250; GO:0004197; GO:0005829; GO:0045087; GO:0019209; GO:0051168; GO:0005634; GO:0048471; GO:0043123; GO:0051092; GO:0050870; GO:0002726; GO:0032743; GO:0043234; GO:0051259; GO:0006508; GO:0050856; GO:0042981; GO:0009620; GO:0002237; GO:0004871; GO:0004842,B-1 B cell differentiation; T cell proliferation; T cell receptor signaling pathway; activation of NF-kappaB-inducing kinase activity; cysteine-type endopeptidase activity; cytosol; innate immune response; kinase activator activity; nuclear export; nucleus; perinuclear region of cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; positive regulation of T cell cytokine production; positive regulation of interleukin-2 production; protein complex; protein oligomerization; proteolysis; regulation of T cell receptor signaling pathway; regulation of apoptotic process; response to fungus; response to molecule of bacterial origin; signal transducer activity; ubiquitin-protein ligase activity,PF13895;,,,,,,,,,MALT1_MOUSE,Mus musculus (Mouse),activation of NF-kappaB-inducing kinase activity [GO:0007250]; B-1 B cell differentiation [GO:0001923]; B cell activation [GO:0042113]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; protein oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; response to molecule of bacterial origin [GO:0002237]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] comp85619_c0_seq1,685,42.4818,0.81434172,17,70,,2.00E-27,A5A8Y8,Epidermal growth factor-like protein 8 (EGF-like protein 8),Epidermal growth factor-like protein 8 (EGF-like protein 8),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF00008;PF07645;PF07546;,,,,,,,,,EGFL8_PIG,Sus scrofa (Pig), comp85629_c0_seq1,704,42.4716,0.38211459,5,78,,1.00E-21,Q503R4,Kelch-like protein 36,Kelch-like protein 36,GO:0016567,protein ubiquitination,PF07707;PF00651;PF01344;,,,,,,,,,KLH36_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein ubiquitination [GO:0016567] comp85645_c1_seq1,359,43.7326,0.58823986,0,25,,,,,,,,,,,9.00E-54,ruditapes2_c3030,,,,,,, comp85650_c0_seq1,318,39.6226,0.56318338,4,0,,,,,,,,,2.00E-26,CHOYP_contig_016497,,,,,,,,, comp85656_c0_seq1,239,36.8201,0.75354537,6,8,,5.00E-24,A0JPA0,Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4),Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4),GO:0030554; GO:0016021; GO:0006811; GO:0005886,adenyl nucleotide binding; integral to membrane; ion transport; plasma membrane,PF00571;PF01595;,,,,,,,,,CNNM4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),ion transport [GO:0006811] comp85670_c1_seq1,371,43.1267,0.41791348,12,0,,1.00E-24,Q8R5H1,Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15),Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15),GO:0030509; GO:0004197; GO:0005737; GO:0035520; GO:0005634; GO:0060389; GO:0007179; GO:0004221; GO:0006511; GO:0004843,BMP signaling pathway; cysteine-type endopeptidase activity; cytoplasm; monoubiquitinated protein deubiquitination; nucleus; pathway-restricted SMAD protein phosphorylation; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;PF14533;,,,,,,,,,UBP15_MOUSE,Mus musculus (Mouse),BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp85676_c0_seq1,204,67.1569,0.79152481,0,3,,1.00E-10,P43712,Malonyl CoA-acyl carrier protein transacylase (MCT) (EC 2.3.1.39),Malonyl CoA-acyl carrier protein transacylase (MCT) (EC 2.3.1.39),GO:0004314; GO:0006633,[acyl-carrier-protein] S-malonyltransferase activity; fatty acid biosynthetic process,PF00698;,,,,,,,,,FABD_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),fatty acid biosynthetic process [GO:0006633] comp85692_c0_seq1,383,43.342,0.50349994,0,23,,9.00E-11,Q622K8,Unconventional myosin heavy chain 6,Unconventional myosin heavy chain 6,GO:0005524; GO:0005737; GO:0003774; GO:0016459; GO:0008134,ATP binding; cytoplasm; motor activity; myosin complex; transcription factor binding,PF00373;PF00612;PF00063;PF00784;,9.00E-31,CHOYP_MYO7A.1.3,,,,,,,HUM6_CAEBR,Caenorhabditis briggsae, comp85692_c0_seq2,254,46.4567,0.60338114,0,0,,4.00E-34,Q29P71,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,,,,,,,,,MYO7A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp85697_c0_seq1,223,54.7085,1.44519035,2,0,,1.00E-15,Q92GI2,Hemolysin C homolog,Hemolysin C homolog,GO:0030554; GO:0050660; GO:0016614,"adenyl nucleotide binding; flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors",PF00571;PF03471;,,,,,,,,,HLYC_RICCN,Rickettsia conorii (strain ATCC VR-613 / Malish 7), comp85711_c0_seq1,232,66.8103,0.97085137,0,21,,2.00E-10,A4VRG3,UPF0312 protein PST_3941,UPF0312 protein PST_3941,GO:0042597,periplasmic space,PF04264;,,,,,,,,,Y3941_PSEU5,Pseudomonas stutzeri (strain A1501), comp85723_c0_seq1,231,42.4242,0.90744856,1,8,,2.00E-12,A7Y2W8,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),GO:0005887; GO:0005328; GO:0005283,integral to plasma membrane; neurotransmitter:sodium symporter activity; sodium:amino acid symporter activity,PF00209;,,,,,,,,,SC6A9_XENLA,Xenopus laevis (African clawed frog), comp85737_c0_seq1,835,43.2335,0.18078494,33,11,,5.00E-30,O88738,Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON),GO:0005794; GO:0006915; GO:0051301; GO:0004869; GO:0005768; GO:0060711; GO:0016020; GO:0005815; GO:0030496; GO:0007067; GO:0043066; GO:0008284; GO:0032465; GO:0000922; GO:0060712; GO:0005802; GO:0004842,Golgi apparatus; apoptotic process; cell division; cysteine-type endopeptidase inhibitor activity; endosome; labyrinthine layer development; membrane; microtubule organizing center; midbody; mitosis; negative regulation of apoptotic process; positive regulation of cell proliferation; regulation of cytokinesis; spindle pole; spongiotrophoblast layer development; trans-Golgi network; ubiquitin-protein ligase activity,PF00653;PF12356;PF00179;,8.00E-23,CHOYP_BRAFLDRAFT_85147.1.1,,,,,,,BIRC6_MOUSE,Mus musculus (Mouse),apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; placenta development [GO:0001890]; positive regulation of cell proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of signal transduction [GO:0009966]; spongiotrophoblast layer development [GO:0060712] comp85756_c0_seq1,232,59.0517,1.29170843,2,10,,4.00E-09,P0A4Y4,Glycogen operon protein GlgX homolog (EC 3.2.1.-),,GO:0043169; GO:0005980; GO:0004133; GO:0004553,"cation binding; glycogen catabolic process; glycogen debranching enzyme activity; hydrolase activity, hydrolyzing O-glycosyl compounds",,,,,,,,,,GLGX_MYCTU,, comp85801_c0_seq1,244,41.8033,0.772579,12,0,,,,,,,,,1.00E-13,CHOYP_NEMVEDRAFT_V1G247129.3.3,,,,,,,,, comp85836_c0_seq1,216,43.0556,0.30195452,4,0,,5.00E-27,P78381,UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),GO:0000139; GO:0005459; GO:0006012; GO:0016021; GO:0005634; GO:0005351,Golgi membrane; UDP-galactose transmembrane transporter activity; galactose metabolic process; integral to membrane; nucleus; sugar:hydrogen symporter activity,PF04142;,5.00E-12,CHOYP_LOC100703978.1.1,,,,,,,S35A2_HUMAN,Homo sapiens (Human),galactose metabolic process [GO:0006012]; UDP-galactose transport [GO:0015785] comp85854_c0_seq1,440,40.6818,0.50702868,11,15,,2.00E-07,Q8BGE5,Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM),Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM),GO:0005524; GO:0008026; GO:0003677; GO:0006281; GO:0071821; GO:0043240; GO:0003682; GO:0004518; GO:0090305; GO:0031297; GO:0000712,ATP binding; ATP-dependent helicase activity; DNA binding; DNA repair; FANCM-MHF complex; Fanconi anaemia nuclear complex; chromatin binding; nuclease activity; nucleic acid phosphodiester bond hydrolysis; replication fork processing; resolution of meiotic recombination intermediates,PF02732;PF16783;PF00271;PF04851;,,,,,,,,,FANCM_MOUSE,Mus musculus (Mouse),DNA repair [GO:0006281]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] comp85864_c0_seq1,225,40,0.44842156,6,5,,7.00E-31,P59723,Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase),Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase),GO:0046872; GO:0005634; GO:0036140; GO:0042265; GO:0042264; GO:0036139; GO:0036138; GO:0048471; GO:0006355; GO:0006351,"metal ion binding; nucleus; peptidyl-asparagine 3-dioxygenase activity; peptidyl-asparagine hydroxylation; peptidyl-aspartic acid hydroxylation; peptidyl-histidine dioxygenase activity; peptidyl-histidine hydroxylation; perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,1.00E-25,CHOYP_HIF1N.1.1,,,,,,,HIF1N_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"negative regulation of vasculature development [GO:1901343]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; transcription, DNA-templated [GO:0006351]" comp85878_c0_seq1,223,43.0493,0.39734724,4,7,,9.00E-11,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp85908_c0_seq1,357,43.1373,1.15425986,13,16,,4.00E-15,Q5U4V1,Ammonium transporter Rh type C (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein),Ammonium transporter Rh type C (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein),GO:0072488; GO:0008519; GO:0016324; GO:0016021,ammonium transmembrane transport; ammonium transmembrane transporter activity; apical plasma membrane; integral to membrane,PF00909;,,,,,,,,,RHCG_XENLA,Xenopus laevis (African clawed frog), comp8592_c0_seq1,405,45.4321,0.19950982,5,1,,5.00E-56,Q9JIS8,Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1),Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1),GO:0016021; GO:0006813; GO:0015379,integral to membrane; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,5.00E-66,CHOYP_S12A4.1.1,,,,,,,S12A4_MOUSE,Mus musculus (Mouse),chemical synaptic transmission [GO:0007268] comp85959_c0_seq1,274,43.7956,0.45884927,3,13,,9.00E-17,Q7TT36,Probable G-protein coupled receptor 125,Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125),GO:0004930; GO:0009897; GO:0016021; GO:0007218,G-protein coupled receptor activity; external side of plasma membrane; integral to membrane; neuropeptide signaling pathway,PF00002;PF07679;PF13855;,,,,,,,,,GP125_MOUSE,Mus musculus (Mouse),cell surface receptor signaling pathway [GO:0007166] comp85960_c0_seq1,330,39.3939,0.31344985,9,0,,2.00E-06,A6QQW0,Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN143_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp85962_c0_seq1,259,47.8764,0.88022146,7,7,,4.00E-09,Q22795,Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43),GO:0009792; GO:0034968; GO:0018024; GO:0005634; GO:0006355; GO:0006351,"embryo development ending in birth or egg hatching; histone lysine methylation; histone-lysine N-methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00856;,,,,,,,,,SET1_CAEEL,Caenorhabditis elegans,"embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp85973_c0_seq1,297,43.4343,0.71842666,3,20,,9.00E-22,Q9UBV7,"Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) [Includes: Xylosylprotein 4-beta-galactosyltransferase (EC 2.4.1.133) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein beta-1,4-galactosyltransferase)]","Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) [Includes: Xylosylprotein 4-beta-galactosyltransferase (EC 2.4.1.133) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein beta-1,4-galactosyltransferase)]",GO:0032580; GO:0000139; GO:0005975; GO:0006464; GO:0030204; GO:0043206; GO:0006024; GO:0016021; GO:0046872; GO:0048147; GO:0006486; GO:0046525,Golgi cisterna membrane; Golgi membrane; carbohydrate metabolic process; cellular protein modification process; chondroitin sulfate metabolic process; extracellular fibril organization; glycosaminoglycan biosynthetic process; integral to membrane; metal ion binding; negative regulation of fibroblast proliferation; protein glycosylation; xylosylprotein 4-beta-galactosyltransferase activity,PF02709;PF13733;,,,,,,,,,B4GT7_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; extracellular fibril organization [GO:0043206]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; negative regulation of fibroblast proliferation [GO:0048147]; protein N-linked glycosylation [GO:0006487]; proteoglycan metabolic process [GO:0006029] comp85989_c0_seq2,223,44.843,0.63125263,0,0,,5.00E-06,Q13263,Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (Tripartite motif-containing protein 28),Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (Tripartite motif-containing protein 28),GO:0003677; GO:0006281; GO:0035851; GO:0060028; GO:0060669; GO:0001837; GO:0000122; GO:0045892; GO:0005719; GO:0005720; GO:0005654; GO:0045739; GO:0042993; GO:0045893; GO:0046777; GO:0004672; GO:0051259; GO:0016925; GO:0043565; GO:0003700; GO:0003713; GO:0003714; GO:0006367; GO:0031625; GO:0004842; GO:0008270,"DNA binding; DNA repair; Krueppel-associated box domain binding; convergent extension involved in axis elongation; embryonic placenta morphogenesis; epithelial to mesenchymal transition; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nuclear euchromatin; nuclear heterochromatin; nucleoplasm; positive regulation of DNA repair; positive regulation of transcription factor import into nucleus; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein kinase activity; protein oligomerization; protein sumoylation; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; transcription initiation from RNA polymerase II promoter; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; zinc ion binding",PF00628;PF00643;PF14634;,,,,,,,,,TIF1B_HUMAN,Homo sapiens (Human),"chromatin modification [GO:0016568]; convergent extension involved in axis elongation [GO:0060028]; DNA methylation involved in embryo development [GO:0043045]; DNA repair [GO:0006281]; embryo implantation [GO:0007566]; embryonic placenta morphogenesis [GO:0060669]; epithelial to mesenchymal transition [GO:0001837]; innate immune response [GO:0045087]; negative regulation of DNA demethylation [GO:1901536]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral release from host cell [GO:1902187]; positive regulation of DNA repair [GO:0045739]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription factor import into nucleus [GO:0042993]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein sumoylation [GO:0016925]; Ras protein signal transduction [GO:0007265]; regulation of genetic imprinting [GO:2000653]; transcription initiation from RNA polymerase II promoter [GO:0006367]" comp85995_c0_seq1,268,42.9104,1.05842878,5,43,,2.00E-13,Q7TS99,Hairy and enhancer of split-related protein HELT (HES/HEY-like transcription factor) (Protein Hes-like) (Protein megane),Hairy and enhancer of split-related protein HELT (HES/HEY-like transcription factor) (Protein Hes-like) (Protein megane),GO:0003677; GO:0021858; GO:0007417; GO:0010467; GO:0035264; GO:0010259; GO:0000122; GO:0005634; GO:0045944; GO:0009791; GO:0042803; GO:0003700; GO:0001967; GO:0005667; GO:0006351,"DNA binding; GABAergic neuron differentiation in basal ganglia; central nervous system development; gene expression; multicellular organism growth; multicellular organismal aging; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; suckling behavior; transcription factor complex; transcription, DNA-dependent",PF07527;PF00010;,1.00E-21,CHOYP_LOC100141592.1.1,,,,,,,HELT_MOUSE,Mus musculus (Mouse),"central nervous system development [GO:0007417]; GABAergic neuron differentiation in basal ganglia [GO:0021858]; gene expression [GO:0010467]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; suckling behavior [GO:0001967]; transcription, DNA-templated [GO:0006351]" comp86014_c1_seq1,252,36.5079,0.83855487,1,6,,7.00E-08,Q01797,Escargot/snail protein homolog (Fragment),Escargot/snail protein homolog (Fragment),GO:0003677; GO:0046872; GO:0005634,DNA binding; metal ion binding; nucleus,PF00096;,,,,,,,,,ESCA_CALVI,Calliphora vicina (Blue blowfly) (Calliphora erythrocephala), comp86021_c0_seq1,652,42.638,0.50960007,17,23,,4.00E-47,Q9P2C4,Transmembrane protein 181,Transmembrane protein 181,GO:0016021; GO:0009405; GO:0015643,integral to membrane; pathogenesis; toxic substance binding,,2.00E-60,CHOYP_CPIPJ_CPIJ015767.1.1,,,,,,,TM181_HUMAN,Homo sapiens (Human),pathogenesis [GO:0009405] comp86022_c0_seq1,205,37.561,1.02151191,7,11,,4.00E-16,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp86032_c0_seq1,407,37.1007,0.42962702,7,29,,4.00E-29,A0JNB1,Zinc finger protein 227,Zinc finger protein 227,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN227_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp86057_c0_seq1,219,66.6667,0.99082569,0,14,,5.00E-17,P16100,Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),GO:0005737; GO:0006097; GO:0004450; GO:0046872; GO:0006099,cytoplasm; glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; metal ion binding; tricarboxylic acid cycle,PF03971;,,,,,,,,,IDH_AZOVI,Azotobacter vinelandii,glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] comp86080_c1_seq1,362,45.5801,1.3010852,0,37,,2.00E-37,A7Y2W8,Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9),GO:0005887; GO:0005328; GO:0005283,integral to plasma membrane; neurotransmitter:sodium symporter activity; sodium:amino acid symporter activity,PF00209;,2.00E-26,CHOYP_SC6A5.4.7,,,,,,,SC6A9_XENLA,Xenopus laevis (African clawed frog), comp86089_c0_seq1,303,61.0561,1.31649374,4,6,,1.00E-33,P63454,3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase 1) (KAS 1),,GO:0004315; GO:0005618; GO:0005829; GO:0019367; GO:0040007; GO:0005886,"3-oxoacyl-[acyl-carrier-protein] synthase activity; cell wall; cytosol; fatty acid elongation, saturated fatty acid; growth; plasma membrane",,,,,,,,,,FAB1_MYCTU,, comp86112_c0_seq1,469,63.9659,0.91915614,0,31,,5.00E-85,Q6A7K8,1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase),1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase),GO:0030604; GO:0070402; GO:0019288; GO:0046872; GO:0016114,"1-deoxy-D-xylulose-5-phosphate reductoisomerase activity; NADPH binding; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; metal ion binding; terpenoid biosynthetic process",PF08436;PF02670;PF13288;,,,,,,,,,DXR_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),"isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]" comp86127_c0_seq1,460,42.1739,0.44138506,24,4,,6.00E-09,Q9UKZ4,Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)],Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)],GO:0005794; GO:0005856; GO:0005783; GO:0005576; GO:0008201; GO:0006955; GO:0005887; GO:0008285; GO:0007399; GO:0007218; GO:0016363; GO:0016607; GO:0048471; GO:0043406; GO:0030838; GO:0051491; GO:0090316; GO:0033138; GO:0046982; GO:0042803; GO:0006359; GO:0006950; GO:0006351,"Golgi apparatus; cytoskeleton; endoplasmic reticulum; extracellular region; heparin binding; immune response; integral to plasma membrane; negative regulation of cell proliferation; nervous system development; neuropeptide signaling pathway; nuclear matrix; nuclear speck; perinuclear region of cytoplasm; positive regulation of MAP kinase activity; positive regulation of actin filament polymerization; positive regulation of filopodium assembly; positive regulation of intracellular protein transport; positive regulation of peptidyl-serine phosphorylation; protein heterodimerization activity; protein homodimerization activity; regulation of transcription from RNA polymerase III promoter; response to stress; transcription, DNA-dependent",PF12661;PF06484;PF15636;,,,,,,,,,TEN1_HUMAN,Homo sapiens (Human),"immune response [GO:0006955]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; neuropeptide signaling pathway [GO:0007218]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription, DNA-templated [GO:0006351]" comp86164_c0_seq1,256,48.0469,0.6043596,6,9,,,,,,,,,2.00E-12,CHOYP_LOC101021639.1.1,,,,,,,,, comp86169_c0_seq1,453,43.2671,0.69366266,18,8,,2.00E-11,Q28832,Low-density lipoprotein receptor (LDL receptor) (Fragment),Low-density lipoprotein receptor (LDL receptor) (Fragment),GO:0005794; GO:0005509; GO:0009986; GO:0008203; GO:0005905; GO:0005769; GO:0006897; GO:0016021; GO:0005770; GO:0006869; GO:0034362; GO:0005764; GO:0005886,Golgi apparatus; calcium ion binding; cell surface; cholesterol metabolic process; coated pit; early endosome; endocytosis; integral to membrane; late endosome; lipid transport; low-density lipoprotein particle; lysosome; plasma membrane,PF07645;PF00057;PF00058;,,,,,,,,,LDLR_PIG,Sus scrofa (Pig),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; transcytosis [GO:0045056] comp86176_c0_seq1,216,43.9815,0.31389294,5,11,,1.00E-12,A2RRU4,Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),GO:0012507; GO:0000139; GO:0032933; GO:0007568; GO:0008203; GO:0005789; GO:0016021; GO:0043231; GO:0043234,ER to Golgi transport vesicle membrane; Golgi membrane; SREBP signaling pathway; aging; cholesterol metabolic process; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bounded organelle; protein complex,PF12349;PF00400;,,,,,,,,,SCAP_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cholesterol metabolic process [GO:0008203]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933] comp86205_c0_seq1,362,53.5912,1.10000839,0,8,,9.00E-08,P71369,Putative metabolite transport protein HI_1104,Putative metabolite transport protein HI_1104,GO:0016021; GO:0005886; GO:0055085; GO:0005215,integral to membrane; plasma membrane; transmembrane transport; transporter activity,PF07690;,,,,,,,,,Y1104_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd),transmembrane transport [GO:0055085] comp86207_c0_seq1,227,55.5066,0.58387817,0,31,,5.00E-15,Q9LZH9,60S ribosomal protein L7a-2,60S ribosomal protein L7a-2,GO:0022625; GO:0042254; GO:0005774,cytosolic large ribosomal subunit; ribosome biogenesis; vacuolar membrane,PF01248;,,,,,,,,,RL7A2_ARATH,Arabidopsis thaliana (Mouse-ear cress),maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412] comp86208_c0_seq1,229,46.2882,0.24784955,7,8,,3.00E-21,Q8VCH6,Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase),Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase),GO:0000139; GO:0007265; GO:0008762; GO:0042987; GO:0006695; GO:0005856; GO:0005829; GO:0050614; GO:0005783; GO:0005789; GO:0019899; GO:0050660; GO:0016021; GO:0030539; GO:0061024; GO:0043066; GO:0008285; GO:0043154; GO:0005634; GO:0016628; GO:0042605; GO:0031639; GO:0008104; GO:0009725; GO:0006979; GO:0043588; GO:0009888,"Golgi membrane; Ras protein signal transduction; UDP-N-acetylmuramate dehydrogenase activity; amyloid precursor protein catabolic process; cholesterol biosynthetic process; cytoskeleton; cytosol; delta24-sterol reductase activity; endoplasmic reticulum; endoplasmic reticulum membrane; enzyme binding; flavin adenine dinucleotide binding; integral to membrane; male genitalia development; membrane organization; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nucleus; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; peptide antigen binding; plasminogen activation; protein localization; response to hormone stimulus; response to oxidative stress; skin development; tissue development",PF01565;,2.00E-16,CHOYP_DHCR24.1.1,,,,,,,DHC24_MOUSE,Mus musculus (Mouse),amyloid precursor protein catabolic process [GO:0042987]; cholesterol biosynthetic process [GO:0006695]; cholesterol metabolic process [GO:0008203]; male genitalia development [GO:0030539]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; oxidation-reduction process [GO:0055114]; plasminogen activation [GO:0031639]; protein localization [GO:0008104]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; response to oxidative stress [GO:0006979]; skin development [GO:0043588]; sterol metabolic process [GO:0016125]; tissue development [GO:0009888] comp86213_c1_seq1,286,44.0559,0.50938757,4,8,,1.00E-15,P42338,"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)","Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)",GO:0016303; GO:0035005; GO:0005524; GO:0038095; GO:0038096; GO:0007186; GO:0050852; GO:0000187; GO:0006914; GO:0006874; GO:0006935; GO:0040016; GO:0007173; GO:0008543; GO:0007156; GO:0045087; GO:0008286; GO:0050900; GO:0048011; GO:0005634; GO:0014065; GO:0005942; GO:0046934; GO:0005886; GO:0070527; GO:0010508; GO:0001952; GO:2000369; GO:0044281,"1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; G-protein coupled receptor signaling pathway; T cell receptor signaling pathway; activation of MAPK activity; autophagy; cellular calcium ion homeostasis; chemotaxis; embryonic cleavage; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; homophilic cell adhesion; innate immune response; insulin receptor signaling pathway; leukocyte migration; neurotrophin TRK receptor signaling pathway; nucleus; phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase complex; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; plasma membrane; platelet aggregation; positive regulation of autophagy; regulation of cell-matrix adhesion; regulation of clathrin-mediated endocytosis; small molecule metabolic process",PF00454;PF00792;PF02192;PF00794;PF00613;,,,,,,,,,PK3CB_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; angiogenesis involved in wound healing [GO:0060055]; autophagy [GO:0006914]; cell migration [GO:0016477]; cellular calcium ion homeostasis [GO:0006874]; chemotaxis [GO:0006935]; embryonic cleavage [GO:0040016]; endothelial cell proliferation [GO:0001935]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of autophagy [GO:0010508]; positive regulation of gene expression [GO:0010628]; regulation of cell-matrix adhesion [GO:0001952]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] comp86216_c0_seq1,623,46.3884,0.29928135,8,7,,1.00E-25,Q8BLN6,Protein unc-80 homolog (mUNC-80),Protein unc-80 homolog (mUNC-80),GO:0016021,integral to membrane,PF15778;,7.00E-41,CHOYP_PHUM_PHUM244880.1.2,,,,,,,UNC80_MOUSE,Mus musculus (Mouse), comp86231_c0_seq1,222,41.4414,0.34361252,4,19,,1.00E-09,Q5R8D5,Transmembrane protein 183,Transmembrane protein 183,GO:0016021,integral to membrane,,,,,,,,,,TM183_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp86233_c0_seq1,346,36.4162,1.39920524,0,44,,1.00E-12,Q9VUL9,"Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)","Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)",GO:0033932; GO:0032580; GO:0005797; GO:0036071; GO:0018392; GO:0016021; GO:0007399; GO:0006486,"1,3-alpha-L-fucosidase activity; Golgi cisterna membrane; Golgi medial cisterna; N-glycan fucosylation; glycoprotein 3-alpha-L-fucosyltransferase activity; integral to membrane; nervous system development; protein glycosylation",PF17039;PF00852;,,,,,,,,,FUCTA_DROME,Drosophila melanogaster (Fruit fly),nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] comp86236_c1_seq1,670,45.0746,0.5592415,2,5,,1.00E-23,Q95YM8,Mushroom body large-type Kenyon cell-specific protein 1,Mushroom body large-type Kenyon cell-specific protein 1,GO:0007613; GO:0005634; GO:0045893; GO:0042803; GO:0043565; GO:0006351,"memory; nucleus; positive regulation of transcription, DNA-dependent; protein homodimerization activity; sequence-specific DNA binding; transcription, DNA-dependent",PF05225;,,,,,,,,,MBLK1_APIME,Apis mellifera (Honeybee),"memory [GO:0007613]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp86236_c1_seq2,603,43.6153,0.52400375,2,0,,2.00E-23,Q95YM8,Mushroom body large-type Kenyon cell-specific protein 1,Mushroom body large-type Kenyon cell-specific protein 1,GO:0007613; GO:0005634; GO:0045893; GO:0042803; GO:0043565; GO:0006351,"memory; nucleus; positive regulation of transcription, DNA-dependent; protein homodimerization activity; sequence-specific DNA binding; transcription, DNA-dependent",PF05225;,8.00E-47,CHOYP_MBLK1.1.1,,,,,,,MBLK1_APIME,Apis mellifera (Honeybee),"memory [GO:0007613]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp86243_c0_seq1,210,36.6667,0.28475679,6,2,,4.00E-15,Q96PQ6,Zinc finger protein 317,Zinc finger protein 317,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN317_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp86261_c0_seq1,352,42.8977,0.49806398,10,14,,3.00E-38,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,3.00E-43,CHOYP_BRAFLDRAFT_98113.1.1,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp86280_c0_seq1,339,40.118,0.59285607,4,23,,8.00E-21,Q9VVE2,Protein rogdi,Protein rogdi,GO:0048149; GO:0005635; GO:0008355,behavioral response to ethanol; nuclear envelope; olfactory learning,PF10259;,4.00E-16,CHOYP_AGAP_AGAP006653.1.1,,,,,,,ROGDI_DROME,Drosophila melanogaster (Fruit fly),behavioral response to ethanol [GO:0048149]; learning or memory [GO:0007611]; olfactory learning [GO:0008355] comp86284_c0_seq1,317,40.3785,0.63363022,1,35,,2.00E-06,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp86311_c0_seq1,237,40.0844,0.52889831,2,0,,1.00E-06,Q54U31,Dual specificity protein kinase shkD (EC 2.7.11.1) (SH2 domain-containing protein 4) (SH2 domain-containing protein D),Dual specificity protein kinase shkD (EC 2.7.11.1) (SH2 domain-containing protein 4) (SH2 domain-containing protein D),GO:0005524; GO:0016020; GO:0018108; GO:0051219; GO:0004674; GO:0004713,ATP binding; membrane; peptidyl-tyrosine phosphorylation; phosphoprotein binding; protein serine/threonine kinase activity; protein tyrosine kinase activity,PF07714;PF00017;,,,,,,,,,SHKD_DICDI,Dictyostelium discoideum (Slime mold), comp86311_c0_seq2,242,42.9752,0.63117961,5,0,,4.00E-26,P53670,LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1),LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1),GO:0005524; GO:0005801; GO:0005829; GO:0005634; GO:0004674; GO:0007286; GO:0008270,ATP binding; cis-Golgi network; cytosol; nucleus; protein serine/threonine kinase activity; spermatid development; zinc ion binding,PF00412;PF00595;PF07714;,2.00E-16,CHOYP_LOC100748762.1.1,,,,,,,LIMK2_RAT,Rattus norvegicus (Rat),protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] comp86345_c0_seq1,325,45.5385,0.89561287,6,33,,7.00E-17,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp86349_c0_seq1,387,45.7364,0.450003,11,10,,1.00E-29,O60336,Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1),Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1),GO:0007256,activation of JNKK activity,PF00400;,,,,,,,,,MABP1_HUMAN,Homo sapiens (Human), comp86349_c1_seq1,295,37.6271,0.0970503,7,0,,,,,,,,,5.00E-33,CHOYP_MABP1.2.2,,,,,,,,, comp86372_c0_seq1,365,46.0274,0.31886402,12,0,,1.00E-32,Q8IV35,WD repeat-containing protein 49,WD repeat-containing protein 49,,,PF00400;,2.00E-65,CHOYP_LOC579391.1.1,,,,,,,WDR49_HUMAN,Homo sapiens (Human), comp86376_c0_seq1,602,38.7043,0.58940012,19,60,,4.00E-27,P08045,Zinc finger protein Xfin (Xenopus fingers protein) (Xfin),Zinc finger protein Xfin (Xenopus fingers protein) (Xfin),GO:0003723; GO:0005737; GO:0046872; GO:0006355,"RNA binding; cytoplasm; metal ion binding; regulation of transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,XFIN_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]" comp86405_c0_seq1,228,39.4737,0.90874764,1,15,,4.00E-08,Q9CQV4,Protein FAM134C,Protein FAM134C,GO:0016021,integral to membrane,,,,,,,,,,F134C_MOUSE,Mus musculus (Mouse),positive regulation of neuron projection development [GO:0010976] comp86412_c0_seq1,414,39.372,0.70123297,18,12,,7.00E-27,P34519,"Putative tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP)","Putative tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP)",GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,4.00E-29,CHOYP_LOC660776.1.1,,,,,,,TXTP_CAEEL,Caenorhabditis elegans,translation [GO:0006412]; transport [GO:0006810] comp86416_c0_seq1,208,45.6731,0.83379587,1,18,,2.00E-07,Q8WMH2,Neuroligin-3 (Gliotactin homolog) (Fragment),Neuroligin-3 (Gliotactin homolog) (Fragment),GO:0007155; GO:0030054; GO:0009986; GO:0005887; GO:0042043; GO:0004872; GO:0045202; GO:0007416,cell adhesion; cell junction; cell surface; integral to plasma membrane; neurexin family protein binding; receptor activity; synapse; synapse assembly,PF00135;,,,,,,,,,NLGN3_MACMU,Macaca mulatta (Rhesus macaque),cell adhesion [GO:0007155] comp86448_c1_seq1,430,41.3953,1.07298798,2,44,,3.00E-12,P34410,TWiK family of potassium channels protein 7,TWiK family of potassium channels protein 7,GO:0016021; GO:0005267,integral to membrane; potassium channel activity,PF07885;,,,,,,,,,TWK7_CAEEL,Caenorhabditis elegans,potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322] comp86473_c0_seq1,201,38.806,0.79896506,0,0,,7.00E-14,Q5T2D3,OTU domain-containing protein 3 (EC 3.4.19.12),OTU domain-containing protein 3 (EC 3.4.19.12),GO:0035871; GO:0044313; GO:0006508; GO:0004843,protein K11-linked deubiquitination; protein K6-linked deubiquitination; proteolysis; ubiquitin-specific protease activity,PF02338;,2.00E-17,CHOYP_LOC755749.1.1,,,,,,,OTUD3_HUMAN,Homo sapiens (Human),protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313] comp86484_c0_seq1,355,38.5915,0.17198204,4,13,,3.00E-47,Q8WVQ1,Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107),Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107),GO:0032580; GO:0005509; GO:0005789; GO:0016021; GO:0043123; GO:0030166; GO:0004871; GO:0045134,Golgi cisterna membrane; calcium ion binding; endoplasmic reticulum membrane; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteoglycan biosynthetic process; signal transducer activity; uridine-diphosphatase activity,PF06079;,,,,,,,,,CANT1_HUMAN,Homo sapiens (Human),positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166] comp86514_c0_seq1,355,47.0423,0.86805049,2,23,,3.00E-74,Q6RUV5,Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),Ras-related C3 botulinum toxin substrate 1 (p21-Rac1),GO:0005525; GO:0003924; GO:0000139; GO:0016601; GO:0060071; GO:0007015; GO:0048532; GO:0002093; GO:0007411; GO:0045453; GO:0008283; GO:0045216; GO:0021799; GO:0090103; GO:0031410; GO:0048813; GO:0071542; GO:0021831; GO:0043652; GO:0003382; GO:0019897; GO:0006972; GO:0030027; GO:0030032; GO:0002551; GO:0042470; GO:0001891; GO:0045740; GO:0030838; GO:0043552; GO:0001934; GO:0030334; GO:0097178; GO:0032587; GO:0034446,"GTP binding; GTPase activity; Golgi membrane; Rac protein signal transduction; Wnt receptor signaling pathway, planar cell polarity pathway; actin filament organization; anatomical structure arrangement; auditory receptor cell morphogenesis; axon guidance; bone resorption; cell proliferation; cell-cell junction organization; cerebral cortex radially oriented cell migration; cochlea morphogenesis; cytoplasmic vesicle; dendrite morphogenesis; dopaminergic neuron differentiation; embryonic olfactory bulb interneuron precursor migration; engulfment of apoptotic cell; epithelial cell morphogenesis; extrinsic to plasma membrane; hyperosmotic response; lamellipodium; lamellipodium assembly; mast cell chemotaxis; melanosome; phagocytic cup; positive regulation of DNA replication; positive regulation of actin filament polymerization; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of protein phosphorylation; regulation of cell migration; ruffle assembly; ruffle membrane; substrate adhesion-dependent cell spreading",PF00071;,2.00E-63,CHOYP_RAC1.3.3,7.00E-68,ruditapes2_c2197,,,,,RAC1_RAT,Rattus norvegicus (Rat),"actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" comp86519_c0_seq1,461,43.3839,0.29568139,10,41,,2.00E-27,Q14393,Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand),Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand),GO:0035754; GO:0005796; GO:0032148; GO:0043277; GO:0060090; GO:0005509; GO:0007050; GO:0008283; GO:0031589; GO:0035690; GO:0071333; GO:0071363; GO:0035457; GO:0009267; GO:0071307; GO:0043027; GO:0097028; GO:0005788; GO:0007167; GO:0085029; GO:0005615; GO:0019064; GO:0097241; GO:0010934; GO:0070168; GO:2000669; GO:2000352; GO:2000270; GO:0032689; GO:0050711; GO:0032715; GO:1900165; GO:1900142; GO:0033159; GO:2000533; GO:0043433; GO:0045892; GO:0032720; GO:0010804; GO:0001764; GO:0031100; GO:0017187; GO:0018105; GO:0001786; GO:0070527; GO:0031093; GO:0002576; GO:0070374; GO:0032008; GO:0001961; GO:2000510; GO:0048146; GO:0010628; GO:0003104; GO:0032825; GO:0033138; GO:0050766; GO:0046827; GO:0051897; GO:0043687; GO:0043491; GO:0072661; GO:0030296; GO:0006508; GO:0048018; GO:0040008; GO:0019079; GO:0046813; GO:0005245,"B cell chemotaxis; Golgi lumen; activation of protein kinase B activity; apoptotic cell clearance; binding, bridging; calcium ion binding; cell cycle arrest; cell proliferation; cell-substrate adhesion; cellular response to drug; cellular response to glucose stimulus; cellular response to growth factor stimulus; cellular response to interferon-alpha; cellular response to starvation; cellular response to vitamin K; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; dendritic cell differentiation; endoplasmic reticulum lumen; enzyme linked receptor protein signaling pathway; extracellular matrix assembly; extracellular space; fusion of virus membrane with host plasma membrane; hematopoietic stem cell migration to bone marrow; macrophage cytokine production; negative regulation of biomineral tissue development; negative regulation of dendritic cell apoptotic process; negative regulation of endothelial cell apoptotic process; negative regulation of fibroblast apoptotic process; negative regulation of interferon-gamma production; negative regulation of interleukin-1 secretion; negative regulation of interleukin-6 production; negative regulation of interleukin-6 secretion; negative regulation of oligodendrocyte apoptotic process; negative regulation of protein import into nucleus, translocation; negative regulation of renal albumin absorption; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor production; negative regulation of tumor necrosis factor-mediated signaling pathway; neuron migration; organ regeneration; peptidyl-glutamic acid carboxylation; peptidyl-serine phosphorylation; phosphatidylserine binding; platelet aggregation; platelet alpha granule lumen; platelet degranulation; positive regulation of ERK1 and ERK2 cascade; positive regulation of TOR signaling cascade; positive regulation of cytokine-mediated signaling pathway; positive regulation of dendritic cell chemotaxis; positive regulation of fibroblast proliferation; positive regulation of gene expression; positive regulation of glomerular filtration; positive regulation of natural killer cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of phagocytosis; positive regulation of protein export from nucleus; positive regulation of protein kinase B signaling cascade; post-translational protein modification; protein kinase B signaling cascade; protein targeting to plasma membrane; protein tyrosine kinase activator activity; proteolysis; receptor agonist activity; regulation of growth; viral genome replication; virion attachment, binding of host cell surface receptor; voltage-gated calcium channel activity",PF07645;PF00594;PF00054;PF02210;,,,,,,,,,GAS6_HUMAN,Homo sapiens (Human),"activation of protein kinase B activity [GO:0032148]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; enzyme linked receptor protein signaling pathway [GO:0007167]; ER to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; organ regeneration [GO:0031100]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein targeting to plasma membrane [GO:0072661]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal peptide processing [GO:0006465]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]" comp86526_c0_seq1,244,32.377,0.78830153,4,13,,1.00E-07,Q9HC56,Protocadherin-9,Protocadherin-9,GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF08374;,,,,,,,,,PCDH9_HUMAN,Homo sapiens (Human),forebrain development [GO:0030900]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp8652_c0_seq1,250,39.2,0.64914832,8,0,,,,,,,,,4.00E-20,CHOYP_LOC764850.4.8,,,,,,,,, comp86532_c0_seq1,222,47.2973,0.08577097,2,0,,3.00E-13,Q8NAG6,Ankyrin repeat and LEM domain-containing protein 1 (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3),Ankyrin repeat and LEM domain-containing protein 1 (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3),,,PF12796;PF03020;,,,,,,,,,ANKL1_HUMAN,Homo sapiens (Human), comp86539_c0_seq1,507,41.6174,0.64537456,10,22,,2.00E-12,Q3TYA6,M-phase phosphoprotein 8,M-phase phosphoprotein 8,GO:0005737; GO:0035064; GO:0045892; GO:0005720; GO:0000788; GO:0005730; GO:0005886; GO:0044030; GO:0006351,"cytoplasm; methylated histone residue binding; negative regulation of transcription, DNA-dependent; nuclear heterochromatin; nuclear nucleosome; nucleolus; plasma membrane; regulation of DNA methylation; transcription, DNA-dependent",PF12796;PF00385;,,,,,,,,,MPP8_MOUSE,Mus musculus (Mouse),"negative regulation of transcription, DNA-templated [GO:0045892]; regulation of DNA methylation [GO:0044030]; transcription, DNA-templated [GO:0006351]" comp86543_c1_seq1,257,44.358,0.47778501,7,0,,,,,,,,,6.00E-18,CHOYP_LOC580708.1.1,,,,,,,,, comp86563_c0_seq1,203,45.3202,1.0650472,3,15,,3.00E-08,Q9R008,Mevalonate kinase (MK) (EC 2.7.1.36),Mevalonate kinase (MK) (EC 2.7.1.36),GO:0005524; GO:0006695; GO:0005829; GO:0019287; GO:0004496; GO:0050728,"ATP binding; cholesterol biosynthetic process; cytosol; isopentenyl diphosphate biosynthetic process, mevalonate pathway; mevalonate kinase activity; negative regulation of inflammatory response",PF08544;PF00288;,,,,,,,,,KIME_MOUSE,Mus musculus (Mouse),"cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]" comp86570_c0_seq1,936,44.8718,0.51112382,50,42,,4.00E-114,Q3U487,E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3),GO:0005634; GO:0048471; GO:0043161; GO:0042787; GO:0004842,nucleus; perinuclear region of cytoplasm; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF03256;PF00632;,1.00E-58,CHOYP_BRAFLDRAFT_276868.1.1,,,,,,,HECD3_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp86578_c0_seq2,374,43.8503,0.72502006,6,15,,2.00E-16,Q96T23,Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex),GO:0034080; GO:0006352; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0005654; GO:0016584; GO:0045893; GO:0050434; GO:0008270,"CENP-A containing nucleosome assembly at centromere; DNA-dependent transcription, initiation; RSF complex; histone binding; negative regulation of DNA binding; negative regulation of transcription, DNA-dependent; nucleoplasm; nucleosome positioning; positive regulation of transcription, DNA-dependent; positive regulation of viral transcription; zinc ion binding",PF00628;PF15612;,,,,,,,,,RSF1_HUMAN,Homo sapiens (Human),"CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]" comp86580_c0_seq1,248,44.3548,0,1,13,,5.00E-07,Q8BGQ7,"Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)","Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)",GO:0005524; GO:0004813; GO:0006419; GO:0016597; GO:0002161; GO:0021680; GO:0005737; GO:0030968; GO:0001942; GO:0046872; GO:0043524; GO:0050885; GO:0006457; GO:0043200; GO:0000049; GO:0006400,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; amino acid binding; aminoacyl-tRNA editing activity; cerebellar Purkinje cell layer development; cytoplasm; endoplasmic reticulum unfolded protein response; hair follicle development; metal ion binding; negative regulation of neuron apoptotic process; neuromuscular process controlling balance; protein folding; response to amino acid stimulus; tRNA binding; tRNA modification,PF02272;PF01411;PF07973;,,,,,,,,,SYAC_MOUSE,Mus musculus (Mouse),alanyl-tRNA aminoacylation [GO:0006419]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; endoplasmic reticulum unfolded protein response [GO:0030968]; hair follicle development [GO:0001942]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; protein folding [GO:0006457]; response to amino acid [GO:0043200]; skin development [GO:0043588]; tRNA modification [GO:0006400] comp86625_c0_seq1,252,45.6349,0.4619671,3,0,,7.00E-07,Q5F226,Protocadherin Fat 2 (FAT tumor suppressor homolog 2),Protocadherin Fat 2 (FAT tumor suppressor homolog 2),GO:0005509; GO:0005913; GO:0010631; GO:0007156; GO:0016021; GO:0005634; GO:0005886,calcium ion binding; cell-cell adherens junction; epithelial cell migration; homophilic cell adhesion; integral to membrane; nucleus; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT2_MOUSE,Mus musculus (Mouse),epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp86638_c0_seq1,251,53.7849,0.81179383,2,16,,6.00E-28,Q923I7,Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2),Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2),GO:0008643; GO:0016021; GO:0006814; GO:0015293,carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF00474;,4.00E-52,CHOYP_ISCW_ISCW012232.1.1,,,,,,,SC5A2_MOUSE,Mus musculus (Mouse), comp86678_c0_seq1,547,40.4022,0.60027164,5,0,,1.00E-98,O35156,UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),GO:0003983; GO:0005737; GO:0046872,UTP:glucose-1-phosphate uridylyltransferase activity; cytoplasm; metal ion binding,PF01704;,2.00E-99,CHOYP_UGPA.1.1,,,,,,,UGPA_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),UDP-glucose metabolic process [GO:0006011] comp86678_c1_seq1,461,39.0456,0.52112039,14,20,,7.00E-48,O59819,Probable UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),Probable UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),GO:0006011; GO:0005829; GO:0016779; GO:0005634,UDP-glucose metabolic process; cytosol; nucleotidyltransferase activity; nucleus,PF01704;,,,1.00E-20,ruditapes_c21281,,,,,UGPA2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),UDP-glucose metabolic process [GO:0006011] comp86708_c0_seq1,507,40.0394,0.88811534,6,63,,7.00E-18,Q9UT67,Inositol phosphoceramide mannosyltransferase 2 (EC 2.4.-.-) (IPC mannosyltransferase 2),Inositol phosphoceramide mannosyltransferase 2 (EC 2.4.-.-) (IPC mannosyltransferase 2),GO:0005794; GO:0033106; GO:0007038; GO:0006897; GO:0016021; GO:0051999; GO:0000030; GO:0031501; GO:0032588,Golgi apparatus; cis-Golgi network membrane; endocytosed protein transport to vacuole; endocytosis; integral to membrane; mannosyl-inositol phosphorylceramide biosynthetic process; mannosyltransferase activity; mannosyltransferase complex; trans-Golgi network membrane,PF04488;,,,,,,,,,IMT2_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),endocytosis [GO:0006897]; mannosyl-inositol phosphorylceramide biosynthetic process [GO:0051999] comp86720_c0_seq1,545,46.789,0.67549405,38,23,,2.00E-23,Q5GJ77,"Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15)","Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15)",GO:0016024; GO:0004366; GO:0016021; GO:0005741; GO:0005886,CDP-diacylglycerol biosynthetic process; glycerol-3-phosphate O-acyltransferase activity; integral to membrane; mitochondrial outer membrane; plasma membrane,PF01553;,,,,,,,,,GPAT1_BOVIN,Bos taurus (Bovine),CDP-diacylglycerol biosynthetic process [GO:0016024] comp86757_c0_seq1,256,55.8594,0.90849776,0,6,,4.00E-19,Q6A6J6,UPF0336 protein PPA1896,UPF0336 protein PPA1896,,,,,,,,,,,,Y1896_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp8675_c0_seq1,258,41.4729,0.54680624,6,0,,8.00E-09,Q6YKA8,Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk),Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk),GO:0005070; GO:0005886; GO:0004871,SH3/SH2 adaptor activity; plasma membrane; signal transducer activity,PF00017;PF00018;,,,,,,,,,DRK_DROSI,Drosophila simulans (Fruit fly), comp86824_c0_seq1,256,62.1094,1.39186577,0,21,,4.00E-31,A0R3I8,Response regulator MprA (Mycobacterial persistence regulator A),Response regulator MprA (Mycobacterial persistence regulator A),GO:0003677; GO:0005737; GO:0035556; GO:0009405; GO:0000156; GO:0006355; GO:0006950; GO:0006351,"DNA binding; cytoplasm; intracellular signal transduction; pathogenesis; phosphorelay response regulator activity; regulation of transcription, DNA-dependent; response to stress; transcription, DNA-dependent",PF00072;PF00486;,,,,,,,,,MPRA_MYCS2,Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155),"pathogenesis [GO:0009405]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp86833_c1_seq1,287,42.5087,0.6274586,11,0,,6.00E-48,O35787,Kinesin-like protein KIF1C (Kinesin-like protein KIF1D),Kinesin-like protein KIF1C (Kinesin-like protein KIF1D),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0007017; GO:0003774,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; microtubule-based process; motor activity,PF00498;PF00225;PF16183;,1.00E-47,CHOYP_LOC100875479.2.2,,,,,,,KIF1C_RAT,Rattus norvegicus (Rat),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] comp86845_c1_seq1,367,42.2343,0.49479359,5,19,,1.00E-33,Q566I1,INO80 complex subunit D,INO80 complex subunit D,GO:0006310; GO:0006281; GO:0005634; GO:0006355; GO:0006351,"DNA recombination; DNA repair; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF13891;,9.00E-50,CHOYP_INO80D.1.1,,,,,,,IN80D_XENLA,Xenopus laevis (African clawed frog),"DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp86886_c0_seq1,513,46.5887,0.66048224,29,2,,2.00E-49,Q15058,Kinesin-like protein KIF14,Kinesin-like protein KIF14,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018; GO:0005634; GO:0005819,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement; nucleus; spindle,PF00498;PF00225;PF16183;,1.00E-30,CHOYP_LOC100371468.1.2,,,,,,,KIF14_HUMAN,Homo sapiens (Human),activation of protein kinase activity [GO:0032147]; cell division [GO:0051301]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebellar granular layer structural organization [GO:0021685]; cerebellar Purkinje cell layer structural organization [GO:0021693]; cerebral cortex development [GO:0021987]; cytoskeleton-dependent intracellular transport [GO:0030705]; establishment of protein localization [GO:0045184]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; mitotic cell cycle process [GO:1903047]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of integrin activation [GO:0033624]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory bulb development [GO:0021772]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell maturation [GO:1903429]; regulation of cell migration [GO:0030334]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of myelination [GO:0031641]; regulation of neuron apoptotic process [GO:0043523]; regulation of Rap protein signal transduction [GO:0032487]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; substrate adhesion-dependent cell spreading [GO:0034446] comp86927_c0_seq1,307,43.6482,0.61806676,0,0,,,,,,,,,2.00E-30,CHOYP_PHUM_PHUM479110.1.1,,,,,,,,, comp86927_c0_seq2,418,43.7799,0.65155875,2,16,,2.00E-45,P12617,"Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)","Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)",GO:0006085; GO:0006633; GO:2001294; GO:0050080; GO:0005759; GO:0005777; GO:0046321,acetyl-CoA biosynthetic process; fatty acid biosynthetic process; malonyl-CoA catabolic process; malonyl-CoA decarboxylase activity; mitochondrial matrix; peroxisome; positive regulation of fatty acid oxidation,PF05292;,,,,,,,,,DCMC_ANSAN,Anser anser anser (Western greylag goose),acetyl-CoA biosynthetic process [GO:0006085]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321] comp86931_c0_seq1,366,39.8907,0.55764899,1,16,,1.00E-07,P17030,Zinc finger protein 25 (Zinc finger protein KOX19),Zinc finger protein 25 (Zinc finger protein KOX19),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZNF25_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp86975_c0_seq1,290,50,1.05235359,0,12,,,,,,,,,,,1.00E-19,ruditapes_c14477,,,,,,, comp87014_c0_seq1,202,68.3168,1.28348772,0,12,,9.00E-14,A6X2G6,HTH-type transcriptional regulator BetI,HTH-type transcriptional regulator BetI,GO:0003677; GO:0019285; GO:0045892; GO:0003700; GO:0006351,"DNA binding; glycine betaine biosynthetic process from choline; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00440;,,,,,,,,,BETI_OCHA4,Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168),"glycine betaine biosynthetic process from choline [GO:0019285]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp8701_c0_seq1,205,44.878,0.29899115,3,0,,5.00E-14,Q13042,Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6),Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6),GO:0005680; GO:0031145; GO:0051301; GO:0008283; GO:0005813; GO:0005829; GO:0007067; GO:0007094; GO:0051436; GO:0005654; GO:0051437; GO:0070979; GO:0005876,anaphase-promoting complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; cell proliferation; centrosome; cytosol; mitosis; mitotic spindle assembly checkpoint; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; nucleoplasm; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; spindle microtubule,,,,,,,,,,CDC16_HUMAN,Homo sapiens (Human),anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of mitotic nuclear division [GO:0007088]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439] comp87073_c0_seq1,273,43.5897,0.94375549,2,23,,7.00E-07,O43301,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_HUMAN,Homo sapiens (Human), comp87081_c0_seq1,455,41.5385,0.20425631,9,21,,1.00E-13,Q6AXM8,Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2),Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2),GO:0004064; GO:0005576; GO:0005764; GO:0016020; GO:0046872; GO:0005739; GO:0005634; GO:0006979,arylesterase activity; extracellular region; lysosome; membrane; metal ion binding; mitochondrion; nucleus; response to oxidative stress,PF01731;,,,,,,,,,PON2_RAT,Rattus norvegicus (Rat),aromatic compound catabolic process [GO:0019439]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636] comp87119_c0_seq1,204,61.7647,1.24749448,0,5,,2.00E-29,Q6A8L2,Imidazole glycerol phosphate synthase subunit HisH (EC 2.4.2.-) (IGP synthase glutamine amidotransferase subunit) (IGP synthase subunit HisH) (ImGP synthase subunit HisH) (IGPS subunit HisH),Imidazole glycerol phosphate synthase subunit HisH (EC 2.4.2.-) (IGP synthase glutamine amidotransferase subunit) (IGP synthase subunit HisH) (ImGP synthase subunit HisH) (IGPS subunit HisH),GO:0005737; GO:0006541; GO:0000105; GO:0000107,cytoplasm; glutamine metabolic process; histidine biosynthetic process; imidazoleglycerol-phosphate synthase activity,PF00117;,,,,,,,,,HIS5_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105] comp87130_c1_seq1,398,41.7085,0.54699508,9,0,,6.00E-16,Q9QYR7,Acyl-coenzyme A thioesterase 3 (Acyl-CoA thioesterase 3) (EC 3.1.2.2) (PTE-Ia) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-CoA thioesterase 2),Acyl-coenzyme A thioesterase 3 (Acyl-CoA thioesterase 3) (EC 3.1.2.2) (PTE-Ia) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-CoA thioesterase 2),GO:0047617; GO:0006637; GO:0004091; GO:0005829; GO:0001676; GO:0016290; GO:0005777; GO:0032788; GO:0032789; GO:0000038,acyl-CoA hydrolase activity; acyl-CoA metabolic process; carboxylesterase activity; cytosol; long-chain fatty acid metabolic process; palmitoyl-CoA hydrolase activity; peroxisome; saturated monocarboxylic acid metabolic process; unsaturated monocarboxylic acid metabolic process; very long-chain fatty acid metabolic process,PF08840;PF04775;,,,,,,,,,ACOT3_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676]; saturated monocarboxylic acid metabolic process [GO:0032788]; unsaturated monocarboxylic acid metabolic process [GO:0032789]; very long-chain fatty acid metabolic process [GO:0000038] comp87136_c0_seq1,661,38.5779,0.7125507,5,87,,3.00E-15,Q5R602,Syntaxin-7,Syntaxin-7,GO:0031901; GO:0016021; GO:0006886; GO:0016192,early endosome membrane; integral to membrane; intracellular protein transport; vesicle-mediated transport,PF05739;,,,,,,,,,STX7_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; vesicle-mediated transport [GO:0016192] comp87137_c1_seq1,225,45.3333,0.4359654,4,0,,4.00E-10,Q9CRG1,Transmembrane 7 superfamily member 3 (NARP1),Transmembrane 7 superfamily member 3 (NARP1),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF13886;,,,,,,,,,TM7S3_MOUSE,Mus musculus (Mouse), comp87140_c0_seq1,331,46.5257,0.39197524,9,0,,2.00E-12,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,,,,,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp87140_c1_seq1,202,50.9901,0.46032874,5,0,,3.00E-10,Q8NFP4,MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3),GO:0046658; GO:0007420; GO:0001764; GO:0021527,anchored to plasma membrane; brain development; neuron migration; spinal cord association neuron differentiation,PF00629;,,,,,,,,,MDGA1_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527] comp87140_c2_seq1,238,46.6387,0.54319141,2,0,,9.00E-09,A2AJA7,Apical endosomal glycoprotein (MAM domain-containing protein 4),Apical endosomal glycoprotein (MAM domain-containing protein 4),GO:0016021; GO:0015031,integral to membrane; protein transport,PF00057;PF00629;,,,,,,,,,AEGP_MOUSE,Mus musculus (Mouse),protein transport [GO:0015031] comp87147_c0_seq1,233,41.6309,0.8062164,0,13,,2.00E-06,Q68CR1,Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3),Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3),GO:0016021,integral to membrane,PF08238;,,,,,,,,,SE1L3_HUMAN,Homo sapiens (Human), comp87160_c0_seq1,313,44.0895,0.59370354,12,4,,4.00E-15,Q8JIY1,Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (xKuz),Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (xKuz),GO:0005798; GO:0007219; GO:0009986; GO:0016021; GO:0006509; GO:0004222; GO:0008237; GO:0007162; GO:0005634; GO:0042803; GO:0019901; GO:0006468; GO:0008270,Golgi-associated vesicle; Notch signaling pathway; cell surface; integral to membrane; membrane protein ectodomain proteolysis; metalloendopeptidase activity; metallopeptidase activity; negative regulation of cell adhesion; nucleus; protein homodimerization activity; protein kinase binding; protein phosphorylation; zinc ion binding,PF00200;PF01562;,,,,,,,,,ADA10_XENLA,Xenopus laevis (African clawed frog),membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cell adhesion [GO:0007162]; Notch signaling pathway [GO:0007219]; protein phosphorylation [GO:0006468] comp87192_c0_seq1,299,43.8127,0.63025915,5,21,,1.00E-10,Q9SCX5,Probable potassium channel AKT5,Probable potassium channel AKT5,GO:0016021; GO:0005249,integral to membrane; voltage-gated potassium channel activity,PF12796;PF00027;PF00520;PF11834;,,,,,,,,,AKT5_ARATH,Arabidopsis thaliana (Mouse-ear cress),regulation of membrane potential [GO:0042391] comp87199_c0_seq1,220,65.9091,0.88401826,0,12,,3.00E-10,P42501,Capsule polysaccharide export inner-membrane protein KpsE,Capsule polysaccharide export inner-membrane protein KpsE,GO:0009276; GO:0006859; GO:0016021; GO:0005886; GO:0015774; GO:0015542,Gram-negative-bacterium-type cell wall; extracellular carbohydrate transport; integral to membrane; plasma membrane; polysaccharide transport; sugar efflux transmembrane transporter activity,,,,,,,,,,KPSE1_ECOLX,Escherichia coli,extracellular carbohydrate transport [GO:0006859]; polysaccharide transport [GO:0015774] comp87201_c0_seq2,384,42.4479,0.11613955,2,34,,5.00E-13,Q80TQ5,Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),GO:0007030; GO:0005737; GO:0005543,Golgi organization; cytoplasm; phospholipid binding,PF00169;PF02759;,,,,,,,,,PKHM2_MOUSE,Mus musculus (Mouse),Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880] comp87227_c0_seq1,281,44.484,0.79539469,5,13,,4.00E-14,Q08AN1,Zinc finger protein 616,Zinc finger protein 616,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN616_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp87246_c0_seq1,202,59.4059,1.5242309,0,5,,6.00E-18,Q9WUA3,6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphofructokinase 1) (Phosphohexokinase),"ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)",GO:0003872; GO:0005945; GO:0005524; GO:0006002; GO:0006096; GO:0046872,6-phosphofructokinase activity; 6-phosphofructokinase complex; ATP binding; fructose 6-phosphate metabolic process; glycolysis; metal ion binding,PF00365;,,,,,,,,,K6PP_MOUSE,Mus musculus (Mouse),fructose 6-phosphate metabolic process [GO:0006002]; glycolytic process through fructose-6-phosphate [GO:0061615]; mitophagy in response to mitochondrial depolarization [GO:0098779] comp87252_c0_seq1,430,43.2558,0.46047258,25,3,,,,,,,,,8.00E-32,CHOYP_LOC100888507.1.1,,,,,,,,, comp87259_c1_seq1,251,45.4183,0.23276232,1,2,,7.00E-43,Q0P5C0,Lipase maturation factor 1 (Transmembrane protein 112),Lipase maturation factor 1 (Transmembrane protein 112),GO:0005789; GO:0016021,endoplasmic reticulum membrane; integral to membrane,PF06762;,3.00E-41,CHOYP_BRAFLDRAFT_200916.1.1,,,,,,,LMF1_BOVIN,Bos taurus (Bovine),chylomicron remnant clearance [GO:0034382]; ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of lipoprotein lipase activity [GO:0051006]; protein glycosylation in Golgi [GO:0033578]; protein maturation [GO:0051604]; protein secretion [GO:0009306]; regulation of cholesterol metabolic process [GO:0090181]; regulation of triglyceride metabolic process [GO:0090207]; triglyceride metabolic process [GO:0006641] comp8725_c0_seq1,250,48.4,0.61756046,7,0,,5.00E-30,P47990,Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)],GO:0051537; GO:0008762; GO:0005829; GO:0009055; GO:0050660; GO:0005506; GO:0030151; GO:0043546; GO:0005777; GO:0034418; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; cytosol; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdenum ion binding; molybdopterin cofactor binding; peroxisome; urate biosynthetic process; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_CHICK,Gallus gallus (Chicken),urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] comp8727_c0_seq1,242,43.8017,0.44851264,2,4,,1.00E-07,Q9Y6X6,Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16),Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16),GO:0005524; GO:0051015; GO:0021549; GO:0005829; GO:0003774; GO:0016459; GO:2000134; GO:0008285; GO:0048812; GO:0005730; GO:0005654; GO:0048471; GO:0014065; GO:0005886,ATP binding; actin filament binding; cerebellum development; cytosol; motor activity; myosin complex; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell proliferation; neuron projection morphogenesis; nucleolus; nucleoplasm; perinuclear region of cytoplasm; phosphatidylinositol 3-kinase cascade; plasma membrane,PF12796;PF00063;,,,,,,,,,MYO16_HUMAN,Homo sapiens (Human),cerebellum development [GO:0021549]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134] comp87280_c0_seq2,304,44.7368,0.33094976,3,0,,1.00E-23,Q5RAY1,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha),Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha),GO:0035005; GO:0005524; GO:0005794; GO:0030136; GO:0005737; GO:0006897; GO:0006887; GO:0005634; GO:0035091; GO:0048015; GO:0005886; GO:0031982,1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; Golgi apparatus; clathrin-coated vesicle; cytoplasm; endocytosis; exocytosis; nucleus; phosphatidylinositol binding; phosphatidylinositol-mediated signaling; plasma membrane; vesicle,PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;,2.00E-31,CHOYP_LOC100121969.1.1,,,,,,,P3C2A_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),endocytosis [GO:0006897]; exocytosis [GO:0006887]; phosphatidylinositol-mediated signaling [GO:0048015] comp87291_c0_seq1,875,44.9143,0.63616641,50,67,,6.00E-100,O88572,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0090245; GO:0046849; GO:0060444; GO:0061310; GO:0061324; GO:0005901; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0060026; GO:0015026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0051593; GO:0048705; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; axis elongation involved in somitogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; caveola; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; convergent extension; coreceptor activity; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; response to folic acid; skeletal system morphogenesis; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,6.00E-31,CHOYP_LRP6.3.6,,,,,,,LRP6_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp87301_c0_seq1,394,42.6396,1.35584397,0,35,,,,,,,,,,,5.00E-19,ruditapes2_c1820,,,,,,, comp87464_c0_seq1,247,45.749,0.78432658,7,18,,6.00E-09,O70546,Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein),Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein),GO:0000978; GO:0060070; GO:0051213; GO:0007507; GO:0071558; GO:0035097; GO:0001701; GO:0048333; GO:0046872; GO:0001843; GO:0048570; GO:0003016; GO:0032525,RNA polymerase II core promoter proximal region sequence-specific DNA binding; canonical Wnt receptor signaling pathway; dioxygenase activity; heart development; histone demethylase activity (H3-K27 specific); histone methyltransferase complex; in utero embryonic development; mesodermal cell differentiation; metal ion binding; neural tube closure; notochord morphogenesis; respiratory system process; somite rostral/caudal axis specification,PF02373;PF13181;,,,,,,,,,KDM6A_MOUSE,Mus musculus (Mouse),canonical Wnt signaling pathway [GO:0060070]; cardiovascular system development [GO:0072358]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] comp87470_c0_seq1,303,44.5545,0.67168208,13,13,,7.00E-29,Q91ZN5,Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Solute carrier family 35 member B2),Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Solute carrier family 35 member B2),GO:0046964; GO:0046963; GO:0000139; GO:0016021; GO:0043123; GO:0004871,3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; 3'-phosphoadenosine 5'-phosphosulfate transport; Golgi membrane; integral to membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transducer activity,PF08449;,1.00E-22,CHOYP_LOC578873.1.1,,,,,,,S35B2_MOUSE,Mus musculus (Mouse),3'-phosphoadenosine 5'-phosphosulfate transport [GO:0046963]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] comp87499_c0_seq1,398,47.4874,0.46084837,12,19,,7.00E-44,Q8BG87,Methylcytosine dioxygenase TET3 (EC 1.14.11.n2),Methylcytosine dioxygenase TET3 (EC 1.14.11.n2),GO:0080111; GO:0044727; GO:0005737; GO:0001939; GO:0080182; GO:0001940; GO:0046872; GO:0070579; GO:0045944; GO:0006493,DNA demethylation; DNA demethylation of male pronucleus; cytoplasm; female pronucleus; histone H3-K4 trimethylation; male pronucleus; metal ion binding; methylcytosine dioxygenase activity; positive regulation of transcription from RNA polymerase II promoter; protein O-linked glycosylation,PF12851;,2.00E-33,CHOYP_TET1.1.1,,,,,,,TET3_MOUSE,Mus musculus (Mouse),DNA demethylation [GO:0080111]; DNA demethylation of male pronucleus [GO:0044727]; histone H3-K4 trimethylation [GO:0080182]; oxidative DNA demethylation [GO:0035511]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein O-linked glycosylation [GO:0006493] comp87540_c0_seq1,252,46.4286,0.8132799,7,0,,5.00E-15,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp87557_c2_seq1,294,36.7347,0.50583576,5,36,,6.00E-06,Q0VA40,Transcription factor Sp9,Transcription factor Sp9,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,SP9_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"embryonic limb morphogenesis [GO:0030326]; embryonic pectoral fin morphogenesis [GO:0035118]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp87564_c0_seq1,312,39.7436,0.6541342,3,33,,3.00E-22,A6QR55,Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4),GO:0005737; GO:0046872; GO:0031397; GO:0005634; GO:0016579; GO:0034394; GO:0031647; GO:0004221; GO:0006511; GO:0004843,cytoplasm; metal ion binding; negative regulation of protein ubiquitination; nucleus; protein deubiquitination; protein localization to cell surface; regulation of protein stability; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;,9.00E-17,CHOYP_UBP15.4.4,,,,,,,UBP4_BOVIN,Bos taurus (Bovine),negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511] comp87603_c0_seq1,203,74.3842,1.04010963,0,6,,2.00E-18,Q21YT7,"Bifunctional enzyme IspD/IspF [Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECDP-synthase) (MECPP-synthase) (MECPS) (EC 4.6.1.12)]","Bifunctional enzyme IspD/IspF [Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECDP-synthase) (MECPP-synthase) (MECPS) (EC 4.6.1.12)]",GO:0008685; GO:0050518; GO:0019288; GO:0046872; GO:0016114,"2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; metal ion binding; terpenoid biosynthetic process",PF01128;PF02542;,,,,,,,,,ISPDF_RHOFD,Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens),"isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]" comp87610_c0_seq1,207,39.1304,0.26839336,7,20,,2.00E-19,Q9GKU5,Histone deacetylase 11 (HD11) (EC 3.5.1.98),Histone deacetylase 11 (HD11) (EC 3.5.1.98),GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0005737; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0006355; GO:0008134; GO:0006351,"NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); cytoplasm; histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; regulation of transcription, DNA-dependent; transcription factor binding; transcription, DNA-dependent",PF00850;,6.00E-23,CHOYP_HDA11.1.1,,,,,,,HDA11_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp87624_c0_seq1,250,35.6,1.18398121,1,4,,,,,,,,,5.00E-19,CHOYP_contig_055049,3.00E-19,ruditapes_c19609,,,,,,, comp87628_c0_seq1,263,43.7262,0.39952151,7,15,,7.00E-08,B2RZ17,F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6),F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6),,,PF12937;PF00400;,,,,,,,,,FBXW2_RAT,Rattus norvegicus (Rat), comp87640_c0_seq1,370,44.5946,0.35333591,5,38,,1.00E-23,Q32KH7,Arylsulfatase I (ASI) (EC 3.1.6.-),Arylsulfatase I (ASI) (EC 3.1.6.-),GO:0005783; GO:0005576; GO:0046872; GO:0008484,endoplasmic reticulum; extracellular region; metal ion binding; sulfuric ester hydrolase activity,PF00884;,,,,,,,,,ARSI_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),metabolic process [GO:0008152] comp87644_c0_seq1,849,40.8716,0.59322116,22,39,,3.00E-26,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp87649_c0_seq1,485,45.9794,0.58980833,19,4,,4.00E-42,Q9BZC7,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0043190; GO:0042626; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0006629; GO:0005765; GO:0005764; GO:0005815; GO:0032383; GO:0006357; GO:0042493; GO:0048545,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lipid metabolic process; lysosomal membrane; lysosome; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus",PF00005;,,,,,,,,,ABCA2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp87700_c0_seq1,268,45.5224,0.44341277,3,16,,7.00E-22,Q9P2K9,Patched domain-containing protein 2 (Protein dispatched homolog 3),Protein dispatched homolog 3 (Patched domain-containing protein 2),GO:0042632; GO:0005783; GO:0008158; GO:0016021; GO:0031965; GO:0032368; GO:0007224,cholesterol homeostasis; endoplasmic reticulum; hedgehog receptor activity; integral to membrane; nuclear membrane; regulation of lipid transport; smoothened signaling pathway,PF03176;PF02460;,,,,,,,,,PTHD2_HUMAN,Homo sapiens (Human),cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; regulation of lipid transport [GO:0032368]; smoothened signaling pathway [GO:0007224] comp87711_c0_seq1,256,64.4531,1.21933296,2,0,,4.00E-17,Q10641,Nicotinate phosphoribosyltransferase pncB1 (NAPRTase pncB1) (EC 6.3.4.21),,GO:0034355; GO:0005618; GO:0016874; GO:0047280; GO:0019358; GO:0004516; GO:0004514,NAD salvage; cell wall; ligase activity; nicotinamide phosphoribosyltransferase activity; nicotinate nucleotide salvage; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity,,,,,,,,,,PNCB1_MYCTU,, comp87729_c0_seq1,490,47.3469,0.82257425,3,38,,1.00E-18,P13395,Spectrin alpha chain,Spectrin alpha chain,GO:0005794; GO:0003779; GO:0051693; GO:0016199; GO:0016323; GO:0005509; GO:0007417; GO:0045169; GO:0045478; GO:0030727; GO:0007294; GO:0005811; GO:0042062; GO:0048790; GO:0008017; GO:0007026; GO:0031594; GO:0007274; GO:0007308; GO:0030707; GO:0007009; GO:0008360; GO:0008091; GO:0045170; GO:0030721,Golgi apparatus; actin binding; actin filament capping; axon midline choice point recognition; basolateral plasma membrane; calcium ion binding; central nervous system development; fusome; fusome organization; germarium-derived female germ-line cyst formation; germarium-derived oocyte fate determination; lipid particle; long-term strengthening of neuromuscular junction; maintenance of presynaptic active zone structure; microtubule binding; negative regulation of microtubule depolymerization; neuromuscular junction; neuromuscular synaptic transmission; oocyte construction; ovarian follicle cell development; plasma membrane organization; regulation of cell shape; spectrin; spectrosome; spectrosome organization,PF13499;PF08726;PF00018;PF00435;,2.00E-27,CHOYP_LOC100377364.2.2,,,,,,,SPTCA_DROME,Drosophila melanogaster (Fruit fly),actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721] comp87753_c0_seq1,396,45.9596,0.53256437,18,3,,9.00E-60,Q6DJR2,Protein WWC2 (WW domain-containing protein 2),Protein WWC2 (WW domain-containing protein 2),,,PF00397;,1.00E-61,CHOYP_LOC100879690.1.1,,,,,,,WWC2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp87767_c1_seq1,334,50,0.87481583,5,16,,2.00E-10,Q8R508,Protocadherin Fat 3 (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF00008;PF02210;,,,,,,,,,FAT3_RAT,Rattus norvegicus (Rat),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp87767_c2_seq1,214,41.1215,0.83986209,4,0,,4.00E-15,Q90953,Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M),GO:0005509; GO:0030246; GO:0007155; GO:0005540; GO:0005578,calcium ion binding; carbohydrate binding; cell adhesion; hyaluronic acid binding; proteinaceous extracellular matrix,PF00008;PF00059;PF00084;PF07686;PF00193;,,,,,,,,,CSPG2_CHICK,Gallus gallus (Chicken),cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] comp87801_c0_seq1,297,61.6162,1.06811247,0,22,,3.00E-63,Q6A5X5,Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI),Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI),GO:0005737; GO:0006094; GO:0004347; GO:0006096,cytoplasm; gluconeogenesis; glucose-6-phosphate isomerase activity; glycolysis,PF00342;,,,,,,,,,G6PI_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096] comp87804_c0_seq1,298,59.7315,1.28750183,2,23,,9.00E-42,P50852,PTS system mannitol-specific EIICB component (EIICB-Mtl) (EII-Mtl) [Includes: Mannitol permease IIC component (PTS system mannitol-specific EIIC component); Mannitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.69) (PTS system mannitol-specific EIIB component)],PTS system mannitol-specific EIICB component (EIICB-Mtl) (EII-Mtl) [Includes: Mannitol permease IIC component (PTS system mannitol-specific EIIC component); Mannitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.197) (PTS system mannitol-specific EIIB component)],GO:0016021; GO:0016301; GO:0009401; GO:0005886; GO:0008982; GO:0005351,integral to membrane; kinase activity; phosphoenolpyruvate-dependent sugar phosphotransferase system; plasma membrane; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; sugar:hydrogen symporter activity,PF02378;PF02302;,,,,,,,,,PTMCB_GEOSE,Geobacillus stearothermophilus (Bacillus stearothermophilus),phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401] comp87810_c0_seq1,557,37.8815,0.4025987,15,22,,2.00E-28,Q9JMD3,PCTP-like protein (PCTP-L) (START domain-containing protein 10) (StARD10) (Serologically defined colon cancer antigen 28 homolog) (StAR-related lipid transfer protein 10),PCTP-like protein (PCTP-L) (START domain-containing protein 10) (StARD10) (Serologically defined colon cancer antigen 28 homolog) (StAR-related lipid transfer protein 10),GO:0005929; GO:0005737; GO:0008289; GO:0006869; GO:0016020,cilium; cytoplasm; lipid binding; lipid transport; membrane,PF01852;,,,,,,,,,PCTL_MOUSE,Mus musculus (Mouse),bile acid secretion [GO:0032782]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360] comp87813_c0_seq1,708,36.7232,1.1333277,19,10,,,,,,,,,,,2.00E-22,ruditapes_c7836,,,,,,, comp87822_c0_seq1,1338,45.142,0.53344872,40,61,,2.00E-125,Q5TYW4,Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog),GO:0009790; GO:0000184,"embryo development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",PF15492;PF08314;,,,,,,,,,NBAS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]" comp87834_c0_seq1,332,38.5542,0.56965326,10,4,,8.00E-20,Q8TDW7,Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3),GO:0005509; GO:0007156; GO:0016021; GO:0007275; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; multicellular organismal development; plasma membrane,PF00028;PF02210;,,,,,,,,,FAT3_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275] comp87864_c0_seq1,331,41.0876,0.50303489,11,32,,,,,,,,,2.00E-20,CHOYP_LOC591426.1.1,,,,,,,,, comp87897_c0_seq1,229,45.4148,0.5151274,0,0,,1.00E-09,P10253,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase],Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase],GO:0004558; GO:0030246; GO:0060048; GO:0002086; GO:0006006; GO:0005980; GO:0007626; GO:0005765; GO:0007040; GO:0032450; GO:0000023; GO:0046716; GO:0050885; GO:0050884; GO:0002026; GO:0005985; GO:0043587; GO:0043181; GO:0055010,alpha-glucosidase activity; carbohydrate binding; cardiac muscle contraction; diaphragm contraction; glucose metabolic process; glycogen catabolic process; locomotory behavior; lysosomal membrane; lysosome organization; maltose alpha-glucosidase activity; maltose metabolic process; muscle cell cellular homeostasis; neuromuscular process controlling balance; neuromuscular process controlling posture; regulation of the force of heart contraction; sucrose metabolic process; tongue morphogenesis; vacuolar sequestering; ventricular cardiac muscle tissue morphogenesis,PF13802;PF01055;PF16863;PF00088;,,,,,,,,,LYAG_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] comp87897_c0_seq2,386,40.9326,0.50000336,8,4,,7.00E-08,Q6P7A9,Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase),GO:0004558; GO:0030246; GO:0005980; GO:0005765; GO:0005764; GO:0032450,alpha-glucosidase activity; carbohydrate binding; glycogen catabolic process; lysosomal membrane; lysosome; maltose alpha-glucosidase activity,PF13802;PF01055;PF16863;PF00088;,,,,,,,,,LYAG_RAT,Rattus norvegicus (Rat),glycogen catabolic process [GO:0005980] comp87944_c0_seq1,503,43.34,0.38191613,29,0,,2.00E-24,Q5XK92,Protein CIP2A homolog,Protein CIP2A homolog,GO:0006526; GO:0005737; GO:0004358; GO:0016021,arginine biosynthetic process; cytoplasm; glutamate N-acetyltransferase activity; integral to membrane,,,,,,,,,,CIP2A_XENLA,Xenopus laevis (African clawed frog), comp87950_c0_seq1,222,45.9459,0.51761205,0,13,,2.00E-36,Q8CFK2,Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1),Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1),GO:0006352; GO:0005634; GO:0045893; GO:0043488; GO:0008270,"DNA-dependent transcription, initiation; nucleus; positive regulation of transcription, DNA-dependent; regulation of mRNA stability; zinc ion binding",PF07741;PF08271;PF00382;,,,,,,,,,TF3B_MOUSE,Mus musculus (Mouse),"regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase III promoter [GO:0006384]" comp87950_c1_seq1,329,45.5927,0.47346205,6,32,,,,,,,,,2.00E-20,CHOYP_BRF1.1.1,,,,,,,,, comp87963_c0_seq1,205,36.5854,0.73363569,5,24,,3.00E-13,Q5REG4,Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3),Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3),GO:0007219; GO:0005737; GO:0016874; GO:0016567; GO:0008270,Notch signaling pathway; cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,,,,,,,,,,DTX3_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] comp88031_c1_seq1,347,55.9078,0.59691748,13,26,,3.00E-14,O75970,Multiple PDZ domain protein (Multi-PDZ domain protein 1),Multiple PDZ domain protein (Multi-PDZ domain protein 1),GO:0043220; GO:0016324; GO:0016327; GO:0007155; GO:0005737; GO:0031410; GO:0030425; GO:0019048; GO:0042552; GO:0014069; GO:0045211; GO:0005923,Schmidt-Lanterman incisure; apical plasma membrane; apicolateral plasma membrane; cell adhesion; cytoplasm; cytoplasmic vesicle; dendrite; modulation by virus of host morphology or physiology; myelination; postsynaptic density; postsynaptic membrane; tight junction,PF09045;PF16667;PF00595;,3.00E-24,CHOYP_MPDZ.3.3,,,,,,,MPDZ_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032] comp88092_c0_seq1,278,48.2014,0.37500485,7,7,,1.00E-13,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp88111_c0_seq1,586,49.8294,0.993048,41,18,,,,,,,,,2.00E-28,CHOYP_LOC100378881.1.1,,,,,,,,, comp88113_c0_seq1,244,40.9836,0.69603442,3,25,,5.00E-29,Q9NRK6,"ATP-binding cassette sub-family B member 10, mitochondrial (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2)","ATP-binding cassette sub-family B member 10, mitochondrial (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2)",GO:0005524; GO:0032592; GO:0005743; GO:0015421,ATP binding; integral to mitochondrial membrane; mitochondrial inner membrane; oligopeptide-transporting ATPase activity,PF00664;PF00005;,,,,,,,,,ABCBA_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085]; transport [GO:0006810] comp88131_c0_seq1,655,39.3893,0.55202389,14,42,,,,,,,,,1.00E-24,CHOYP_BTBD17.1.1,,,,,,,,, comp88140_c0_seq1,404,39.1089,1.43133407,5,30,,4.00E-10,Q7SZ59,Ras-like protein family member 12 (RAS-like protein Ris),Ras-like protein family member 12 (RAS-like protein Ris),GO:0005525; GO:0003924; GO:0016020; GO:0007264,GTP binding; GTPase activity; membrane; small GTPase mediated signal transduction,PF00071;,7.00E-20,CHOYP_RASLC.1.1,,,,,,,RASLC_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),small GTPase mediated signal transduction [GO:0007264] comp88142_c1_seq1,222,46.8468,0.83107276,0,2,,4.00E-09,Q9BVR0,Putative HERC2-like protein 3,Putative HERC2-like protein 3,GO:0046872; GO:0004842,metal ion binding; ubiquitin-protein ligase activity,PF06701;,,,,,,,,,HRC23_HUMAN,Homo sapiens (Human), comp88147_c0_seq1,569,37.4341,0.30185442,8,45,,3.00E-57,Q95KC8,T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Fragment),T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin) (Fragment),GO:0005576; GO:0016021; GO:0005886,extracellular region; integral to membrane; plasma membrane,,2.00E-46,CHOYP_ITFG1.1.1,,,,,,,TIP_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp88222_c0_seq1,245,43.6735,0.08939102,7,9,,3.00E-27,Q9QYM7,DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4),DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4),GO:0003684; GO:0000724; GO:0004519; GO:0032205; GO:0000784; GO:0000110; GO:0006295; GO:0006296; GO:0009411; GO:0003697,"damaged DNA binding; double-strand break repair via homologous recombination; endonuclease activity; negative regulation of telomere maintenance; nuclear chromosome, telomeric region; nucleotide-excision repair factor 1 complex; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; response to UV; single-stranded DNA binding",PF02732;,,,,,,,,,XPF_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),"double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; response to UV [GO:0009411]" comp88231_c0_seq1,313,38.6581,0.68860352,2,10,,1.00E-09,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp88232_c0_seq1,251,47.012,0.58334259,9,0,,7.00E-37,Q9WVL6,Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3),Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3),GO:0001888; GO:0015012; GO:0016021; GO:0031227; GO:0046872,glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; metal ion binding,PF03016;PF09258;,2.00E-17,CHOYP_EXTL3.1.1,,,,,,,EXTL3_MOUSE,Mus musculus (Mouse),glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] comp88232_c1_seq1,207,49.2754,0.56523058,8,0,,,,,,,,,1.00E-20,CHOYP_LOC100121031.2.2,,,,,,,,, comp88254_c0_seq1,316,35.7595,0.30325559,5,8,,3.00E-33,P08630,Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C) (Dsrc29a),Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C) (Dsrc29a),GO:0005524; GO:0042023; GO:0007254; GO:0030036; GO:0007349; GO:0007619; GO:0005737; GO:0008340; GO:0007391; GO:0007301; GO:0045172; GO:0008258; GO:0007485; GO:0007476; GO:0030717; GO:0046872; GO:0004715; GO:0007424; GO:0030723; GO:0005543; GO:0005886; GO:0004713; GO:0030833; GO:0007435; GO:0046960,ATP binding; DNA endoreduplication; JNK cascade; actin cytoskeleton organization; cellularization; courtship behavior; cytoplasm; determination of adult lifespan; dorsal closure; female germline ring canal formation; germline ring canal; head involution; imaginal disc-derived male genitalia development; imaginal disc-derived wing morphogenesis; karyosome formation; metal ion binding; non-membrane spanning protein tyrosine kinase activity; open tracheal system development; ovarian fusome organization; phospholipid binding; plasma membrane; protein tyrosine kinase activity; regulation of actin filament polymerization; salivary gland morphogenesis; sensitization,PF00779;PF00169;PF07714;PF00017;PF00018;,7.00E-31,CHOYP_BTKL.1.1,,,,,,,BTKL_DROME,Drosophila melanogaster (Fruit fly),"actin cytoskeleton organization [GO:0030036]; cellularization [GO:0007349]; courtship behavior [GO:0007619]; determination of adult lifespan [GO:0008340]; DNA endoreduplication [GO:0042023]; dorsal closure [GO:0007391]; female germline ring canal formation [GO:0007301]; head involution [GO:0008258]; imaginal disc-derived male genitalia development [GO:0007485]; imaginal disc-derived wing morphogenesis [GO:0007476]; innate immune response [GO:0045087]; JNK cascade [GO:0007254]; karyosome formation [GO:0030717]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian fusome organization [GO:0030723]; ovarian nurse cell to oocyte transport [GO:0007300]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of cell proliferation [GO:0042127]; regulation of imaginal disc-derived wing size [GO:0044719]; salivary gland morphogenesis [GO:0007435]; sensitization [GO:0046960]; spiracle morphogenesis, open tracheal system [GO:0035277]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" comp88254_c1_seq1,275,42.1818,0.492424,5,7,,2.00E-28,P24604,Tyrosine-protein kinase Tec (EC 2.7.10.2),Tyrosine-protein kinase Tec (EC 2.7.10.2),GO:0005524; GO:0005856; GO:0005829; GO:0035556; GO:0046872; GO:0004715; GO:0018108; GO:0005543; GO:0005886,ATP binding; cytoskeleton; cytosol; intracellular signal transduction; metal ion binding; non-membrane spanning protein tyrosine kinase activity; peptidyl-tyrosine phosphorylation; phospholipid binding; plasma membrane,PF00779;PF00169;PF07714;PF00017;PF00018;,,,,,,,,,TEC_MOUSE,Mus musculus (Mouse),adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of platelet activation [GO:0010543]; tissue regeneration [GO:0042246]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp88262_c0_seq1,459,38.5621,0.53474808,12,3,,2.00E-21,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,1.00E-55,CHOYP_NEMVEDRAFT_V1G244806.2.2,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp88275_c0_seq1,225,48.4444,0.38993179,6,5,,3.00E-25,P54802,Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form],GO:0004561; GO:0005975; GO:0021680; GO:0006027; GO:0060119; GO:0045475; GO:0043202; GO:0007040; GO:0042474; GO:0007399; GO:0046548; GO:0044281,alpha-N-acetylglucosaminidase activity; carbohydrate metabolic process; cerebellar Purkinje cell layer development; glycosaminoglycan catabolic process; inner ear receptor cell development; locomotor rhythm; lysosomal lumen; lysosome organization; middle ear morphogenesis; nervous system development; retinal rod cell development; small molecule metabolic process,PF05089;PF12972;PF12971;,3.00E-14,CHOYP_NAGLU.2.2,,,,,,,ANAG_HUMAN,Homo sapiens (Human),cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] comp88281_c0_seq1,364,44.5055,0.50137741,6,49,,8.00E-07,Q9Y6N8,Cadherin-10 (T2-cadherin),Cadherin-10 (T2-cadherin),GO:0034332; GO:0005509; GO:0034329; GO:0007156; GO:0016021; GO:0005886,adherens junction organization; calcium ion binding; cell junction assembly; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF01049;,,,,,,,,,CAD10_HUMAN,Homo sapiens (Human),adherens junction organization [GO:0034332]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp88299_c0_seq1,308,38.3117,0.98665772,1,29,,2.00E-11,Q58DI9,ADP-ribosylation factor-like protein 11,ADP-ribosylation factor-like protein 11,GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00025;,,,,,,,,,ARL11_BOVIN,Bos taurus (Bovine),small GTPase mediated signal transduction [GO:0007264] comp88299_c1_seq1,231,41.5584,0.62619257,1,26,,6.00E-23,P61208,ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like 7),ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like 7),GO:0005525; GO:0043014; GO:0005737; GO:0032456; GO:0030175; GO:0005886; GO:0007264,GTP binding; alpha-tubulin binding; cytoplasm; endocytic recycling; filopodium; plasma membrane; small GTPase mediated signal transduction,PF00025;,,,,,,,,,ARL4C_MOUSE,Mus musculus (Mouse),endocytic recycling [GO:0032456]; small GTPase mediated signal transduction [GO:0007264] comp88302_c0_seq1,562,45.1957,0.32681992,35,1,,5.00E-16,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,5.00E-30,CHOYP_LOC584771.1.1,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp88311_c0_seq1,706,43.0595,0.61297158,20,26,,2.00E-92,Q7SXV1,TBC1 domain family member 23,TBC1 domain family member 23,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;PF00581;,1.00E-63,CHOYP_LOC100375955.1.1,,,,,,,TBC23_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp88314_c0_seq1,637,40.5024,0.61713471,13,41,,3.00E-24,A9JR56,CDC42 small effector protein 2,CDC42 small effector protein 2,GO:0005737; GO:0005856; GO:0005886; GO:0008360; GO:0009966; GO:0005198,cytoplasm; cytoskeleton; plasma membrane; regulation of cell shape; regulation of signal transduction; structural molecule activity,PF00786;,,,,,,,,,C42S2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),regulation of cell shape [GO:0008360]; regulation of signal transduction [GO:0009966]; signal transduction [GO:0007165] comp88321_c1_seq1,230,45.2174,0.25975004,5,0,,9.00E-33,A2CI34,Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),GO:0005524; GO:0005737; GO:0018108; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00069;,4.00E-32,CHOYP_NEMVEDRAFT_V1G241055.1.1,,,,,,,DUSTY_PIMPR,Pimephales promelas (Fathead minnow),embryonic organ development [GO:0048568] comp88324_c0_seq1,256,45.7031,0.90653941,1,11,,4.00E-21,P18173,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660; GO:0004344; GO:0006006; GO:0008364; GO:0046693,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding; glucose dehydrogenase activity; glucose metabolic process; pupal chitin-based cuticle development; sperm storage,PF05199;PF00732;,,,,,,,,,DHGL_DROME,Drosophila melanogaster (Fruit fly),cuticle development [GO:0042335]; glucose metabolic process [GO:0006006]; pupal chitin-based cuticle development [GO:0008364]; sensory perception of pain [GO:0019233]; sperm storage [GO:0046693] comp88330_c0_seq1,352,46.5909,0.95924687,21,17,,6.00E-13,P97924,Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain),GO:0005524; GO:0005089; GO:0007409; GO:0005856; GO:0005085; GO:0035556; GO:0046872; GO:0043005; GO:0043025; GO:0048471; GO:0005543; GO:0004674; GO:0035023; GO:0050773,ATP binding; Rho guanyl-nucleotide exchange factor activity; axonogenesis; cytoskeleton; guanyl-nucleotide exchange factor activity; intracellular signal transduction; metal ion binding; neuron projection; neuronal cell body; perinuclear region of cytoplasm; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; regulation of dendrite development,PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;,,,,,,,,,KALRN_RAT,Rattus norvegicus (Rat),axonogenesis [GO:0007409]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023] comp88345_c0_seq2,547,43.3272,0.6749769,9,10,,2.00E-40,Q0V989,Coiled-coil domain-containing protein 85C,Coiled-coil domain-containing protein 85C,GO:0007275,multicellular organismal development,PF10226;,1.00E-44,CHOYP_CC85C.1.1,,,,,,,CC85C_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),multicellular organism development [GO:0007275] comp8834_c0_seq1,283,45.9364,0.41754993,5,0,,,,,,,,,,,1.00E-31,ruditapes2_c2440,,,,,,, comp88406_c0_seq1,469,49.2537,0.38773238,21,5,,1.00E-07,O46339,Homeobox protein homothorax (Homeobox protein dorsotonals),Homeobox protein homothorax (Homeobox protein dorsotonals),GO:0003677; GO:0003705; GO:0007420; GO:0001752; GO:0005737; GO:0048735; GO:0007480; GO:0007476; GO:0007479; GO:0005634; GO:0007422; GO:0045944; GO:0000060; GO:0042659; GO:0045664; GO:0007432; GO:0043565; GO:0007525; GO:0010092; GO:0007383; GO:0005667,"DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; brain development; compound eye photoreceptor fate commitment; cytoplasm; haltere morphogenesis; imaginal disc-derived leg morphogenesis; imaginal disc-derived wing morphogenesis; leg disc proximal/distal pattern formation; nucleus; peripheral nervous system development; positive regulation of transcription from RNA polymerase II promoter; protein import into nucleus, translocation; regulation of cell fate specification; regulation of neuron differentiation; salivary gland boundary specification; sequence-specific DNA binding; somatic muscle development; specification of organ identity; specification of segmental identity, antennal segment; transcription factor complex",PF05920;PF16493;,1.00E-48,CHOYP_LOC100374249.1.1,3.00E-30,ruditapes_c29026,,,,,HTH_DROME,Drosophila melanogaster (Fruit fly),"brain development [GO:0007420]; compound eye development [GO:0048749]; compound eye photoreceptor fate commitment [GO:0001752]; eye development [GO:0001654]; haltere morphogenesis [GO:0048735]; head morphogenesis [GO:0060323]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; leg disc proximal/distal pattern formation [GO:0007479]; peripheral nervous system development [GO:0007422]; positive regulation of decapentaplegic signaling pathway [GO:0090098]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus, translocation [GO:0000060]; protein localization to nucleus [GO:0034504]; proximal/distal pattern formation [GO:0009954]; regulation of cell fate specification [GO:0042659]; regulation of neuron differentiation [GO:0045664]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; salivary gland boundary specification [GO:0007432]; segmentation [GO:0035282]; somatic muscle development [GO:0007525]; specification of organ identity [GO:0010092]; specification of segmental identity, antennal segment [GO:0007383]; specification of segmental identity, head [GO:0007380]" comp8843_c0_seq1,206,42.233,0.21905278,4,0,,7.00E-19,Q8NE09,Regulator of G-protein signaling 22 (RGS22),Regulator of G-protein signaling 22 (RGS22),GO:0005096; GO:0005737; GO:0005886; GO:0038032,GTPase activator activity; cytoplasm; plasma membrane; termination of G-protein coupled receptor signaling pathway,PF00615;,1.00E-13,CHOYP_RGS22.1.2,,,,,,,RGS22_HUMAN,Homo sapiens (Human),negative regulation of signal transduction [GO:0009968] comp88449_c1_seq1,233,44.206,0.65001197,5,6,,,,,,,,,,,4.00E-11,ruditapes_c19123,,,,,,, comp88461_c0_seq1,502,38.8446,0.85471877,8,27,,1.00E-17,P17871,TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit),TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit),GO:0003677; GO:0001169; GO:0000120; GO:0000991; GO:0000995; GO:0005669; GO:0000126; GO:0006367; GO:0006384,DNA binding; RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity; RNA polymerase I transcription factor complex; core RNA polymerase II binding transcription factor activity; core RNA polymerase III binding transcription factor activity; transcription factor TFIID complex; transcription factor TFIIIB complex; transcription initiation from RNA polymerase II promoter; transcription initiation from RNA polymerase III promoter,PF00352;,,,,,,,,,TBP_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript [GO:1903357]; transcription from RNA polymerase I promoter [GO:0006360]; transcription initiation from RNA polymerase III promoter [GO:0006384]; transcription initiation from RNA polymerase II promoter [GO:0006367] comp88469_c0_seq1,207,58.9372,1.23013624,0,5,,5.00E-08,P25737,Lysine-specific permease,Lysine-specific permease,GO:1902022; GO:0015171; GO:0016021; GO:0005886,L-lysine transport; amino acid transmembrane transporter activity; integral to membrane; plasma membrane,PF00324;,,,,,,,,,LYSP_ECOLI,Escherichia coli (strain K12),protein homooligomerization [GO:0051260] comp88477_c0_seq1,684,35.5263,0.3832176,16,24,,2.00E-09,Q9HC07,Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL),Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL),GO:0005794; GO:0032472; GO:0000139; GO:0006874; GO:0031901; GO:0010008; GO:0016021; GO:0031902; GO:0005765; GO:0006487; GO:0035751; GO:0032588,Golgi apparatus; Golgi calcium ion transport; Golgi membrane; cellular calcium ion homeostasis; early endosome membrane; endosome membrane; integral to membrane; late endosome membrane; lysosomal membrane; protein N-linked glycosylation; regulation of lysosomal lumen pH; trans-Golgi network membrane,PF01169;,,,,,,,,,TM165_HUMAN,Homo sapiens (Human),cellular calcium ion homeostasis [GO:0006874]; Golgi calcium ion transport [GO:0032472]; protein N-linked glycosylation [GO:0006487]; regulation of lysosomal lumen pH [GO:0035751] comp88485_c0_seq2,350,43.1429,0.49280852,3,6,,3.00E-23,Q9NP87,DNA-directed DNA/RNA polymerase mu (Pol Mu) (EC 2.7.7.7) (Terminal transferase),DNA-directed DNA/RNA polymerase mu (Pol Mu) (EC 2.7.7.7) (Terminal transferase),GO:0030183; GO:0003677; GO:0006310; GO:0006281; GO:0003887; GO:0046872; GO:0005634; GO:0016446,B cell differentiation; DNA binding; DNA recombination; DNA repair; DNA-directed DNA polymerase activity; metal ion binding; nucleus; somatic hypermutation of immunoglobulin genes,PF14792;PF14791;PF10391;PF14716;,,,,,,,,,DPOLM_HUMAN,Homo sapiens (Human),B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp88489_c0_seq1,873,35.2806,0.40709742,0,317,,,,,,,,,,,1.00E-49,ruditapes_c23951,,,,,,, comp88524_c0_seq1,355,64.507,1.08786196,0,10,,3.00E-17,Q88IU8,Acyl-homoserine lactone acylase PvdQ (AHL acylase PvdQ) (Acyl-HSL acylase PvdQ) (EC 3.5.1.97) [Cleaved into: Acyl-homoserine lactone acylase PvdQ subunit alpha (Acyl-HSL acylase PvdQ subunit alpha); Acyl-homoserine lactone acylase PvdQ subunit beta (Acyl-HSL acylase PvdQ subunit beta)],Acyl-homoserine lactone acylase PvdQ (AHL acylase PvdQ) (Acyl-HSL acylase PvdQ) (EC 3.5.1.97) [Cleaved into: Acyl-homoserine lactone acylase PvdQ subunit alpha (Acyl-HSL acylase PvdQ subunit alpha); Acyl-homoserine lactone acylase PvdQ subunit beta (Acyl-HSL acylase PvdQ subunit beta)],GO:0017000; GO:0016811; GO:0042597; GO:0009372,"antibiotic biosynthetic process; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; periplasmic space; quorum sensing",PF01804;,,,,,,,,,PVDQ_PSEPK,Pseudomonas putida (strain KT2440),antibiotic biosynthetic process [GO:0017000]; quorum sensing [GO:0009372] comp88533_c0_seq4,286,50,0.5072725,2,0,,7.00E-31,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,7.00E-31,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp88543_c0_seq1,324,45.0617,0.43683212,10,10,,6.00E-26,Q5ZLG9,WD repeat-containing protein 59,WD repeat-containing protein 59,,,PF00400;,,,,,,,,,WDR59_CHICK,Gallus gallus (Chicken),cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008] comp8856_c0_seq1,345,51.5942,0.39318512,6,0,,8.00E-47,Q8TE73,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,6.00E-64,CHOYP_LOC577371.1.2,,,,,,,DYH5_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp88572_c0_seq1,225,62.6667,1.05224751,1,4,,8.00E-24,P65567,NADH-quinone oxidoreductase subunit F (EC 1.6.99.5) (NADH dehydrogenase I subunit F) (NDH-1 subunit F),,GO:0051539; GO:0010181; GO:0051287; GO:0008137; GO:0046872; GO:0048038,"4 iron, 4 sulfur cluster binding; FMN binding; NAD binding; NADH dehydrogenase (ubiquinone) activity; metal ion binding; quinone binding",,,,,,,,,,NUOF_MYCTU,, comp88577_c1_seq1,240,46.25,0.63463906,0,4,,2.00E-07,P07271,ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (Petite integration frequency protein 1) (Telomere stability protein 1),ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (Petite integration frequency protein 1) (Telomere stability protein 1),GO:0005524; GO:0003678; GO:0051880; GO:0000727; GO:0000002; GO:0005743; GO:0031966; GO:0032211; GO:0005730; GO:0005634; GO:0010521; GO:0000723,ATP binding; DNA helicase activity; G-quadruplex DNA binding; double-strand break repair via break-induced replication; mitochondrial genome maintenance; mitochondrial inner membrane; mitochondrial membrane; negative regulation of telomere maintenance via telomerase; nucleolus; nucleus; telomerase inhibitor activity; telomere maintenance,PF05970;,,,,,,,,,PIF1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),chromosome organization [GO:0051276]; DNA recombination [GO:0006310]; DNA strand renaturation [GO:0000733]; double-strand break repair via break-induced replication [GO:0000727]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomere maintenance via telomerase [GO:0032211]; replication fork reversal [GO:0071932]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] comp88587_c0_seq1,440,45.2273,0.40458925,9,23,,4.00E-70,Q03468,DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB),GO:0005524; GO:0003677; GO:0008094; GO:0007256; GO:0007257; GO:0006284; GO:0003682; GO:0004386; GO:0008630; GO:0035264; GO:0005730; GO:0045494; GO:0032786; GO:0032403; GO:0006290; GO:0009411; GO:0010224; GO:0010165; GO:0010332; GO:0006979; GO:0000303; GO:0009636; GO:0008023; GO:0006366; GO:0006283,"ATP binding; DNA binding; DNA-dependent ATPase activity; activation of JNKK activity; activation of JUN kinase activity; base-excision repair; chromatin binding; helicase activity; intrinsic apoptotic signaling pathway in response to DNA damage; multicellular organism growth; nucleolus; photoreceptor cell maintenance; positive regulation of DNA-dependent transcription, elongation; protein complex binding; pyrimidine dimer repair; response to UV; response to UV-B; response to X-ray; response to gamma radiation; response to oxidative stress; response to superoxide; response to toxic substance; transcription elongation factor complex; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair",PF00271;PF00176;,2.00E-58,CHOYP_ERCC6.1.1,,,,,,,ERCC6_HUMAN,Homo sapiens (Human),"activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]" comp88587_c1_seq2,346,45.6647,0.45204742,2,15,,3.00E-28,Q759G7,Helicase SWR1 (EC 3.6.4.12),Helicase SWR1 (EC 3.6.4.12),GO:0005524; GO:0003677; GO:0016568; GO:0004386; GO:0005634; GO:0006355; GO:0006351,"ATP binding; DNA binding; chromatin modification; helicase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00271;PF07529;PF00176;,,,,,,,,,SWR1_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),"histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp88590_c0_seq1,1071,40.7096,1.06522429,3,646,female>male,,,,,,,,4.00E-85,CHOYP_ODPX.1.1,,,,,,,,, comp88597_c0_seq1,532,41.7293,0.60740955,13,19,,2.00E-19,Q64259,Von Hippel-Lindau disease tumor suppressor (pVHL),Von Hippel-Lindau disease tumor suppressor (pVHL),GO:0030891; GO:0001525; GO:0043534; GO:0005829; GO:0030198; GO:0016020; GO:0005739; GO:0000122; GO:0030182; GO:0005634; GO:0010498; GO:0051291; GO:0016567; GO:0042069; GO:0045471; GO:0001666; GO:0008134; GO:0005667,VCB complex; angiogenesis; blood vessel endothelial cell migration; cytosol; extracellular matrix organization; membrane; mitochondrion; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; nucleus; proteasomal protein catabolic process; protein heterooligomerization; protein ubiquitination; regulation of catecholamine metabolic process; response to ethanol; response to hypoxia; transcription factor binding; transcription factor complex,PF01847;,,,,,,,,,VHL_RAT,Rattus norvegicus (Rat),"angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; ciliary body morphogenesis [GO:0061073]; extracellular matrix organization [GO:0030198]; eye pigmentation [GO:0048069]; homeostasis of number of retina cells [GO:0048877]; iris morphogenesis [GO:0061072]; melanin metabolic process [GO:0006582]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902072]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; NLS-bearing protein import into nucleus [GO:0006607]; pancreatic A cell differentiation [GO:0003310]; positive regulation of epithelial cell proliferation [GO:0050679]; proteasomal protein catabolic process [GO:0010498]; protein heterooligomerization [GO:0051291]; protein ubiquitination [GO:0016567]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of catecholamine metabolic process [GO:0042069]; regulation of cellular protein localization [GO:1903827]; regulation of transcription, DNA-templated [GO:0006355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; type B pancreatic cell differentiation [GO:0003309]" comp88643_c0_seq1,324,42.5926,0.62274385,11,0,,4.00E-12,A1L0Z0,Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1),Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF10744;,,,,,,,,,MED1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"cellular response to thyroid hormone stimulus [GO:0097067]; transcription, DNA-templated [GO:0006351]" comp88643_c1_seq1,262,45.0382,0.60599961,8,5,,9.00E-14,Q172G3,Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1),Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1),GO:0001104; GO:0016592,RNA polymerase II transcription cofactor activity; mediator complex,PF10744;,,,,,,,,,MED1_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),"transcription, DNA-templated [GO:0006351]" comp88653_c0_seq1,253,58.498,0.7956638,1,11,,8.00E-08,P40979,Putative ABC transporter permease protein ORF1 (Fragment),Putative ABC transporter permease protein ORF1 (Fragment),GO:0016021; GO:0005886; GO:0005215,integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,YOR1_CALSR,Caldicellulosiruptor sp. (strain Rt8B.4),transport [GO:0006810] comp88656_c0_seq1,360,41.9444,0.66926731,2,1,,2.00E-31,Q0P5N1,Protein canopy homolog 3,Protein canopy homolog 3,GO:0005783; GO:0045087,endoplasmic reticulum; innate immune response,PF11938;,3.00E-30,CHOYP_LOC100184874.1.1,,,,,,,CNPY3_BOVIN,Bos taurus (Bovine),innate immune response [GO:0045087] comp88656_c0_seq2,348,37.931,0.68098123,0,0,,,,,,,,,1.00E-28,CHOYP_LOC100184874.1.1,,,,,,,,, comp88660_c0_seq1,356,44.9438,0.75945616,18,379,,,,,,,,,1.00E-67,CHOYP_LOC100843429.2.2,,,,,,,,, comp88680_c1_seq1,312,35.2564,0.31041641,6,0,,,,,,,,,,,6.00E-11,ruditapes2_c1288,,,,,,, comp88691_c0_seq1,465,45.3763,0.68278704,30,25,,9.00E-13,Q90610,Neogenin (Fragment),Neogenin (Fragment),GO:0007155; GO:0016021; GO:0005886,cell adhesion; integral to membrane; plasma membrane,PF00041;PF07679;PF06583;,,,,,,,,,NEO1_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; positive regulation of BMP signaling pathway [GO:0030513] comp88705_c0_seq1,364,46.4286,0.4620288,10,9,,1.00E-15,Q90687,Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2),Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2),GO:0000077; GO:0038127; GO:0000187; GO:0036302; GO:0007409; GO:0007420; GO:0005737; GO:0048013; GO:0060325; GO:0048806; GO:0042593; GO:0042445; GO:0009755; GO:0048839; GO:0048609; GO:0051463; GO:0060125; GO:0046676; GO:0048011; GO:0004726; GO:0005634; GO:0035265; GO:2001275; GO:0046887; GO:0033628; GO:0040014; GO:0046825; GO:0006641,DNA damage checkpoint; ERBB signaling pathway; activation of MAPK activity; atrioventricular canal development; axonogenesis; brain development; cytoplasm; ephrin receptor signaling pathway; face morphogenesis; genitalia development; glucose homeostasis; hormone metabolic process; hormone-mediated signaling pathway; inner ear development; multicellular organismal reproductive process; negative regulation of cortisol secretion; negative regulation of growth hormone secretion; negative regulation of insulin secretion; neurotrophin TRK receptor signaling pathway; non-membrane spanning protein tyrosine phosphatase activity; nucleus; organ growth; positive regulation of glucose import in response to insulin stimulus; positive regulation of hormone secretion; regulation of cell adhesion mediated by integrin; regulation of multicellular organism growth; regulation of protein export from nucleus; triglyceride metabolic process,PF00017;PF00102;,,,,,,,,,PTN11_CHICK,Gallus gallus (Chicken),abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; face morphogenesis [GO:0060325]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of hormone secretion [GO:0046887]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of multicellular organism growth [GO:0040014]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; triglyceride metabolic process [GO:0006641] comp88706_c0_seq1,482,41.4938,0.39412654,10,4,,1.00E-67,Q6GLR7,Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),GO:0030054; GO:0030659; GO:0006887; GO:0046872; GO:0005543; GO:0015031; GO:0045202,cell junction; cytoplasmic vesicle membrane; exocytosis; metal ion binding; phospholipid binding; protein transport; synapse,PF06292;PF00169;,3.00E-76,CHOYP_LOC100372028.1.1,,,,,,,CAPS1_XENLA,Xenopus laevis (African clawed frog),dense core granule exocytosis [GO:1990504]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079] comp88757_c0_seq1,251,52.1912,0.53390678,7,0,,7.00E-11,O15031,Plexin-B2 (MM1),Plexin-B2 (MM1),GO:0005096; GO:0007420; GO:0005887; GO:0005622; GO:0001843; GO:0007405; GO:0043547; GO:0050772; GO:0032319; GO:0008360; GO:2001222; GO:0001932; GO:0017154,GTPase activator activity; brain development; integral to plasma membrane; intracellular; neural tube closure; neuroblast proliferation; positive regulation of GTPase activity; positive regulation of axonogenesis; regulation of Rho GTPase activity; regulation of cell shape; regulation of neuron migration; regulation of protein phosphorylation; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB2_HUMAN,Homo sapiens (Human),brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp88757_c1_seq1,416,48.3173,0.49643144,9,9,,2.00E-14,Q9V4A7,Plexin-B,Plexin-B,GO:0016021; GO:0005622; GO:0008045; GO:0035021; GO:0005886; GO:0035025; GO:0004872; GO:0007165,integral to membrane; intracellular; motor neuron axon guidance; negative regulation of Rac protein signal transduction; plasma membrane; positive regulation of Rho protein signal transduction; receptor activity; signal transduction,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; negative regulation of Rac protein signal transduction [GO:0035021]; olfactory bulb axon guidance [GO:0071678]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374] comp88773_c0_seq1,237,67.5105,0.89475277,0,5,,6.00E-49,A1W6R1,Molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase),Molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase),GO:0005525; GO:0006777; GO:0005737; GO:0070568; GO:0046872,GTP binding; Mo-molybdopterin cofactor biosynthetic process; cytoplasm; guanylyltransferase activity; metal ion binding,PF12804;,,,,,,,,,MOBA_ACISJ,Acidovorax sp. (strain JS42),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp88798_c0_seq1,230,37.3913,0.81291859,7,11,,5.00E-28,Q15831,Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19),Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19),GO:0005524; GO:0051645; GO:0032147; GO:0043276; GO:0006914; GO:0007409; GO:0060070; GO:0007050; GO:0005737; GO:0005829; GO:0006112; GO:0030010; GO:0042593; GO:0008286; GO:0072332; GO:0000287; GO:0016020; GO:0005739; GO:0030308; GO:0008285; GO:0060770; GO:0005634; GO:0002039; GO:0050772; GO:0045722; GO:0030511; GO:0046777; GO:0043234; GO:0051291; GO:0030295; GO:0004674; GO:0030111; GO:0042304; GO:0051896; GO:0006974; GO:0033762; GO:0010212; GO:0033993; GO:0044281; GO:0007286; GO:0001894; GO:0001944,ATP binding; Golgi localization; activation of protein kinase activity; anoikis; autophagy; axonogenesis; canonical Wnt receptor signaling pathway; cell cycle arrest; cytoplasm; cytosol; energy reserve metabolic process; establishment of cell polarity; glucose homeostasis; insulin receptor signaling pathway; intrinsic apoptotic signaling pathway by p53 class mediator; magnesium ion binding; membrane; mitochondrion; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation involved in prostate gland development; nucleus; p53 binding; positive regulation of axonogenesis; positive regulation of gluconeogenesis; positive regulation of transforming growth factor beta receptor signaling pathway; protein autophosphorylation; protein complex; protein heterooligomerization; protein kinase activator activity; protein serine/threonine kinase activity; regulation of Wnt receptor signaling pathway; regulation of fatty acid biosynthetic process; regulation of protein kinase B signaling cascade; response to DNA damage stimulus; response to glucagon stimulus; response to ionizing radiation; response to lipid; small molecule metabolic process; spermatid development; tissue homeostasis; vasculature development,PF00069;,,,,,,,,,STK11_HUMAN,Homo sapiens (Human),activation of protein kinase activity [GO:0032147]; anoikis [GO:0043276]; autophagy [GO:0006914]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV-B [GO:0071493]; dendrite extension [GO:0097484]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; Golgi localization [GO:0051645]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; positive regulation of axonogenesis [GO:0050772]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of dendrite morphogenesis [GO:0048814]; regulation of protein kinase B signaling [GO:0051896]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; T cell receptor signaling pathway [GO:0050852]; TCR signalosome assembly [GO:0036399]; tissue homeostasis [GO:0001894]; vasculature development [GO:0001944] comp88806_c0_seq1,240,45,0.6898152,0,16,,3.00E-15,P18433,Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48),GO:0007411; GO:0008286; GO:0005887; GO:0006468; GO:0005001,axon guidance; insulin receptor signaling pathway; integral to plasma membrane; protein phosphorylation; transmembrane receptor protein tyrosine phosphatase activity,PF00102;,,,,,,,,,PTPRA_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165] comp88817_c0_seq1,280,44.6429,0.36155891,2,5,,4.00E-20,C4XGV9,Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK),Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK),GO:0005524; GO:0019563; GO:0004370; GO:0006071; GO:0006072,ATP binding; glycerol catabolic process; glycerol kinase activity; glycerol metabolic process; glycerol-3-phosphate metabolic process,PF02782;PF00370;,4.00E-34,CHOYP_BRAFLDRAFT_224325.3.3,,,,,,,GLPK_DESMR,Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1),glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071] comp88817_c1_seq1,260,47.6923,0.50082978,1,1,,6.00E-34,Q14409,"Putative glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase, testis specific 1)","Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1)",GO:0005524; GO:0019563; GO:0004370; GO:0006071; GO:0006072; GO:0005741,ATP binding; glycerol catabolic process; glycerol kinase activity; glycerol metabolic process; glycerol-3-phosphate metabolic process; mitochondrial outer membrane,PF02782;PF00370;,,,,,,,,,GLPK3_HUMAN,Homo sapiens (Human),glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; triglyceride metabolic process [GO:0006641] comp88817_c2_seq1,223,47.0852,0.16434667,6,9,,4.00E-29,B1MFT1,Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK),Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK),GO:0005524; GO:0019563; GO:0004370; GO:0006071; GO:0006072,ATP binding; glycerol catabolic process; glycerol kinase activity; glycerol metabolic process; glycerol-3-phosphate metabolic process,PF02782;PF00370;,,,,,,,,,GLPK_MYCA9,Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543),glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071] comp88829_c1_seq1,266,36.0902,1.05953878,0,13,,1.00E-09,Q9Y661,Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (3-OST-4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4),Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (3-OST-4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4),GO:0000139; GO:0008467; GO:0005576; GO:0030201; GO:0016021,Golgi membrane; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; extracellular region; heparan sulfate proteoglycan metabolic process; integral to membrane,PF00685;,,,,,,,,,HS3S4_HUMAN,Homo sapiens (Human),heparan sulfate proteoglycan metabolic process [GO:0030201] comp88831_c1_seq1,209,45.933,0.36522575,2,0,,4.00E-25,Q93099,"Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)","Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)",GO:0006559; GO:0034641; GO:0005829; GO:0004411; GO:0046872; GO:0006572,"L-phenylalanine catabolic process; cellular nitrogen compound metabolic process; cytosol; homogentisate 1,2-dioxygenase activity; metal ion binding; tyrosine catabolic process",PF04209;,4.00E-13,CHOYP_BRAFLDRAFT_73486.1.1,,,,,,,HGD_HUMAN,Homo sapiens (Human),L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] comp88844_c1_seq1,510,43.1373,0.51100196,9,10,,8.00E-94,O46470,Regulator of G-protein signaling 7 (RGS7),Regulator of G-protein signaling 7 (RGS7),GO:0007186; GO:0005096; GO:0005737; GO:0044292; GO:0005834; GO:0035556; GO:0005634; GO:0005886; GO:0004871; GO:0038032,G-protein coupled receptor signaling pathway; GTPase activator activity; cytoplasm; dendrite terminus; heterotrimeric G-protein complex; intracellular signal transduction; nucleus; plasma membrane; signal transducer activity; termination of G-protein coupled receptor signaling pathway,PF00610;PF00631;PF00615;,8.00E-128,CHOYP_LOC655987.2.3,,,,,,,RGS7_BOVIN,Bos taurus (Bovine),G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968] comp88882_c0_seq1,428,39.9533,0.88030576,2,29,,7.00E-11,A0PJY2,Fez family zinc finger protein 1 (Zinc finger protein 312B),Fez family zinc finger protein 1 (Zinc finger protein 312B),GO:0000978; GO:0007411; GO:0021797; GO:0046872; GO:0008285; GO:0000122; GO:0001764; GO:0005634; GO:0021772; GO:0045666; GO:0045893; GO:0006351,"RNA polymerase II core promoter proximal region sequence-specific DNA binding; axon guidance; forebrain anterior/posterior pattern specification; metal ion binding; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; neuron migration; nucleus; olfactory bulb development; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,FEZF1_HUMAN,Homo sapiens (Human),"axon guidance [GO:0007411]; forebrain anterior/posterior pattern specification [GO:0021797]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp88886_c0_seq1,1574,49.5553,0.42556644,2,16,,,,,,,,,3.00E-37,CHOYP_PHUM_PHUM292420.1.1,,,,,,,,, comp88886_c0_seq2,1703,49.266,0.4661205,16,12,,2.00E-40,P83038,Histone deacetylase 4 (HD4) (EC 3.5.1.98),Histone deacetylase 4 (HD4) (EC 3.5.1.98),GO:0030183; GO:0032041; GO:0097372; GO:0046969; GO:0046970; GO:0070932; GO:0070933; GO:0004407; GO:0000118; GO:0006954; GO:0046872; GO:0045843; GO:0045892; GO:0007399; GO:0008134; GO:0006351,"B cell differentiation; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone H3 deacetylation; histone H4 deacetylation; histone deacetylase activity; histone deacetylase complex; inflammatory response; metal ion binding; negative regulation of striated muscle tissue development; negative regulation of transcription, DNA-dependent; nervous system development; transcription factor binding; transcription, DNA-dependent",PF12203;PF00850;,,,,,,,,,HDAC4_CHICK,Gallus gallus (Chicken),"B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; inflammatory response [GO:0006954]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]" comp88910_c0_seq1,253,32.0158,0.61952187,5,0,,1.00E-06,Q6ZN30,Zinc finger protein basonuclin-2,Zinc finger protein basonuclin-2,GO:0003677; GO:0005737; GO:0046872; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"DNA binding; cytoplasm; metal ion binding; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,5.00E-25,CHOYP_LOC100378553.1.1,,,,,,,BNC2_HUMAN,Homo sapiens (Human),"endochondral bone growth [GO:0003416]; mesenchyme development [GO:0060485]; palate development [GO:0060021]; regulation of transcription, DNA-templated [GO:0006355]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]" comp88933_c0_seq1,222,40.5405,0.66206192,0,17,,,,,,,,,2.00E-22,CHOYP_contig_006788,,,,,,,,, comp88969_c2_seq1,598,37.9599,0.37655299,25,36,,9.00E-69,Q32L27,Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2),Ubiquitin-conjugating enzyme E2 Q2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q2) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2),GO:0005524; GO:0005737; GO:0070936; GO:0004842,ATP binding; cytoplasm; protein K48-linked ubiquitination; ubiquitin-protein ligase activity,PF00179;,6.00E-61,CHOYP_ISCW_ISCW000642.1.1,,,,,,,UB2Q2_BOVIN,Bos taurus (Bovine),protein K48-linked ubiquitination [GO:0070936] comp88986_c0_seq1,309,62.4595,1.16542574,0,15,,6.00E-11,P37512,Uncharacterized protein YyaL,Uncharacterized protein YyaL,GO:0006013; GO:0004476,mannose metabolic process; mannose-6-phosphate isomerase activity,PF03190;,,,,,,,,,YYAL_BACSU,Bacillus subtilis (strain 168), comp88988_c0_seq1,954,44.5493,0.62376195,17,3,,2.00E-169,Q5SPC5,Otoferlin (Fer-1-like protein 2),Otoferlin (Fer-1-like protein 2),GO:0016323; GO:0005509; GO:0030054; GO:0005789; GO:0016021; GO:0016079; GO:0030672,basolateral plasma membrane; calcium ion binding; cell junction; endoplasmic reticulum membrane; integral to membrane; synaptic vesicle exocytosis; synaptic vesicle membrane,PF00168;PF08150;PF08151;PF16165;,0,CHOYP_OTOF.1.1,,,,,,,OTOF_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),neuromuscular process controlling balance [GO:0050885]; response to auditory stimulus [GO:0010996]; synaptic vesicle exocytosis [GO:0016079] comp88988_c0_seq2,764,45.4188,0.5686589,0,0,,1.00E-26,Q17388,Sperm vesicle fusion protein fer-1,Sperm vesicle fusion protein fer-1,GO:0030154; GO:0031301; GO:0005887; GO:0061025; GO:0007275; GO:0032809; GO:0007009; GO:0031260; GO:0031268; GO:0030317; GO:0007283,cell differentiation; integral to organelle membrane; integral to plasma membrane; membrane fusion; multicellular organismal development; neuronal cell body membrane; plasma membrane organization; pseudopodium membrane; pseudopodium organization; sperm motility; spermatogenesis,PF00168;PF08165;PF08150;PF16165;,2.00E-24,CHOYP_MYOF.1.3,,,,,,,FER1_CAEEL,Caenorhabditis elegans,cell differentiation [GO:0030154]; membrane fusion [GO:0061025]; multicellular organism development [GO:0007275]; plasma membrane organization [GO:0007009]; pseudopodium organization [GO:0031268]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317] comp89004_c0_seq1,385,43.1169,0.73010823,4,20,,2.00E-28,Q5R621,Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-),Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-),GO:0000139; GO:0016021; GO:0008146,Golgi membrane; integral to membrane; sulfotransferase activity,PF03567;,,,,,,,,,HS2ST_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp89025_c0_seq1,1838,28.6725,0.34964033,1636,2996,,8.00E-53,Q9Z336,Dynein light chain Tctex-type 1 (Activator of G-protein signaling 2) (AGS2) (T-complex testis-specific protein 1 homolog),Dynein light chain Tctex-type 1 (Activator of G-protein signaling 2) (AGS2) (T-complex testis-specific protein 1 homolog),GO:0005794; GO:0051301; GO:0005868; GO:0000132; GO:0006886; GO:0019060; GO:0005874; GO:0007067; GO:0003774; GO:0050768; GO:0048812; GO:0008277; GO:0032314; GO:0051493; GO:0005819,Golgi apparatus; cell division; cytoplasmic dynein complex; establishment of mitotic spindle orientation; intracellular protein transport; intracellular transport of viral proteins in host cell; microtubule; mitosis; motor activity; negative regulation of neurogenesis; neuron projection morphogenesis; regulation of G-protein coupled receptor protein signaling pathway; regulation of Rac GTPase activity; regulation of cytoskeleton organization; spindle,PF03645;,1.00E-82,CHOYP_LOC100370790.1.1,4.00E-104,ruditapes2_c1749,,,,,DYLT1_RAT,Rattus norvegicus (Rat),cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; intracellular protein transport [GO:0006886]; intracellular transport of viral protein in host cell [GO:0019060]; mitotic nuclear division [GO:0007067]; negative regulation of neurogenesis [GO:0050768]; neuron projection morphogenesis [GO:0048812]; regulation of cytoskeleton organization [GO:0051493]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of GTPase activity [GO:0043087] comp89035_c0_seq1,508,49.2126,0.55382959,29,9,,8.00E-13,Q6IEE6,Transmembrane protein 132E,Transmembrane protein 132E,GO:0016021,integral to membrane,PF16070;PF15706;PF15705;,,,,,,,,,T132E_MOUSE,Mus musculus (Mouse), comp89053_c0_seq1,1221,41.1957,0.56608453,67,31,,0,Q6ZMV9,Kinesin-like protein KIF6,Kinesin-like protein KIF6,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0003777; GO:0007018,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule motor activity; microtubule-based movement,PF00225;,0,CHOYP_KIF6.1.1,,,,,,,KIF6_HUMAN,Homo sapiens (Human),microtubule-based movement [GO:0007018] comp89061_c1_seq1,472,42.3729,0.19245331,12,5,,1.00E-37,Q9UK97,F-box only protein 9 (Cross-immune reaction antigen 1) (Renal carcinoma antigen NY-REN-57),F-box only protein 9 (Cross-immune reaction antigen 1) (Renal carcinoma antigen NY-REN-57),GO:0019005; GO:0031146; GO:0005737; GO:0032006; GO:0004842,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cytoplasm; regulation of TOR signaling cascade; ubiquitin-protein ligase activity,PF12937;,3.00E-18,CHOYP_FBX9.1.1,,,,,,,FBX9_HUMAN,Homo sapiens (Human),fat cell differentiation [GO:0045444]; innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of TOR signaling [GO:0032006]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp89061_c1_seq2,337,43.0267,0.32600596,0,6,,3.00E-07,Q9XI00,F-box protein 7 (SKP1-interacting partner 32),F-box protein 7 (SKP1-interacting partner 32),GO:0005739; GO:0005634; GO:0090406; GO:0016567; GO:0006417; GO:0009409; GO:0009408,mitochondrion; nucleus; pollen tube; protein ubiquitination; regulation of translation; response to cold; response to heat,PF12937;,,,,,,,,,SKI32_ARATH,Arabidopsis thaliana (Mouse-ear cress),protein ubiquitination [GO:0016567]; regulation of translation [GO:0006417]; response to cold [GO:0009409]; response to heat [GO:0009408] comp89066_c0_seq1,238,59.2437,1.06224098,1,2,,2.00E-21,C5BR54,Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase),Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase),GO:0033743; GO:0008270,peptide-methionine (R)-S-oxide reductase activity; zinc ion binding,PF01641;,,,,,,,,,MSRB_TERTT,Teredinibacter turnerae (strain ATCC 39867 / T7901),protein repair [GO:0030091]; response to oxidative stress [GO:0006979] comp89085_c0_seq1,221,50.2262,0.72788376,7,197,,2.00E-16,Q8TGM6,Protein TAR1 (Transcript antisense to ribosomal RNA protein 1),Protein TAR1 (Transcript antisense to ribosomal RNA protein 1),GO:0005739; GO:0043457,mitochondrion; regulation of cellular respiration,,1.00E-33,CHOYP_LOC100214376.1.1,,,,,,,TAR1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),regulation of cellular respiration [GO:0043457] comp89085_c1_seq1,358,48.0447,0.70392706,7,179,,,,,,,,,5.00E-27,CHOYP_RNA45S5.1.4,,,,,,,,, comp89087_c1_seq2,270,34.0741,0.25663231,0,0,,3.00E-07,A2VD33,Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase),Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase),GO:0006777; GO:0008265; GO:0030151; GO:0043545; GO:0030170; GO:0016740,Mo-molybdopterin cofactor biosynthetic process; Mo-molybdopterin cofactor sulfurase activity; molybdenum ion binding; molybdopterin cofactor metabolic process; pyridoxal phosphate binding; transferase activity,PF00266;PF03473;PF03476;,,,,,,,,,MOCOS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),molybdopterin cofactor metabolic process [GO:0043545]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp89101_c0_seq1,606,46.3696,0.52280009,21,16,,6.00E-88,Q93063,Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2),Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2),GO:0000139; GO:0050509; GO:0030154; GO:0005789; GO:0050508; GO:0006024; GO:0042328; GO:0015014; GO:0016021; GO:0031227; GO:0001707; GO:0001503; GO:0006486; GO:0007165,"Golgi membrane; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; cell differentiation; endoplasmic reticulum membrane; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; glycosaminoglycan biosynthetic process; heparan sulfate N-acetylglucosaminyltransferase activity; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; integral to membrane; intrinsic to endoplasmic reticulum membrane; mesoderm formation; ossification; protein glycosylation; signal transduction",PF03016;PF09258;,3.00E-45,CHOYP_EXT2.1.1,,,,,,,EXT2_HUMAN,Homo sapiens (Human),"cell differentiation [GO:0030154]; cellular polysaccharide biosynthetic process [GO:0033692]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; mesoderm formation [GO:0001707]; ossification [GO:0001503]; protein glycosylation [GO:0006486]; signal transduction [GO:0007165]" comp89102_c0_seq1,305,58.6885,0.9574571,0,27,,1.00E-58,Q6A780,Error-prone DNA polymerase (EC 2.7.7.7),Error-prone DNA polymerase (EC 2.7.7.7),GO:0008408; GO:0003677; GO:0006281; GO:0006260; GO:0003887; GO:0005737,3'-5' exonuclease activity; DNA binding; DNA repair; DNA replication; DNA-directed DNA polymerase activity; cytoplasm,PF07733;PF14579;PF02811;PF01336;,,,,,,,,,DNAE2_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA repair [GO:0006281]; DNA replication [GO:0006260] comp89121_c0_seq1,263,58.9354,1.31913966,0,21,,2.00E-16,Q9T0A7,UDP-glucose 4-epimerase 2 (AtUGE2) (EC 5.1.3.2) (UDP-galactose 4-epimerase 2),UDP-glucose 4-epimerase 2 (AtUGE2) (EC 5.1.3.2) (UDP-galactose 4-epimerase 2),GO:0003978; GO:0042546; GO:0044237; GO:0050662; GO:0005829; GO:0006012,UDP-glucose 4-epimerase activity; cell wall biogenesis; cellular metabolic process; coenzyme binding; cytosol; galactose metabolic process,PF16363;,,,,,,,,,GALE3_ARATH,Arabidopsis thaliana (Mouse-ear cress),cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; galactose metabolic process [GO:0006012] comp89125_c0_seq2,439,43.7358,0.23965266,2,0,,4.00E-13,Q803E0,Paladin,Paladin,GO:0001525; GO:0005829,angiogenesis; cytosol,,,,,,,,,,PALD_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525] comp89125_c1_seq1,314,43.3121,0.47779466,6,3,,2.00E-14,Q9ULE6,Paladin,Paladin,GO:0005829,cytosol,,8.00E-18,CHOYP_LOC100563071.1.1,,,,,,,PALD_HUMAN,Homo sapiens (Human), comp89126_c0_seq1,316,41.7722,0.14584917,2,24,,3.00E-11,Q5REC2,Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (Prohormone convertase 2) (Proprotein convertase 2) (PC2),Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (Prohormone convertase 2) (Proprotein convertase 2) (PC2),GO:0034230; GO:0005615; GO:0030070; GO:0016020; GO:0007399; GO:0016540; GO:0006508; GO:0004252; GO:0030133,enkephalin processing; extracellular space; insulin processing; membrane; nervous system development; protein autoprocessing; proteolysis; serine-type endopeptidase activity; transport vesicle,PF01483;PF00082;PF16470;,,,,,,,,,NEC2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),enkephalin processing [GO:0034230]; insulin processing [GO:0030070]; nervous system development [GO:0007399]; protein autoprocessing [GO:0016540] comp89126_c0_seq2,395,44.3038,0.21052767,1,15,,8.00E-11,P51559,Endoprotease bli-4 (EC 3.4.21.-) (Blisterase) (Blistered cuticle protein 4),Endoprotease bli-4 (EC 3.4.21.-) (Blisterase) (Blistered cuticle protein 4),GO:0040002; GO:0016021; GO:0005634; GO:0006508; GO:0004252,collagen and cuticulin-based cuticle development; integral to membrane; nucleus; proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,,,,,,,,,BLI4_CAEEL,Caenorhabditis elegans,collagen and cuticulin-based cuticle development [GO:0040002] comp89126_c1_seq1,209,43.5407,0.30732411,4,0,,2.00E-07,Q16549,Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7),GO:0030173; GO:0016486; GO:0006508; GO:0004252,integral to Golgi membrane; peptide hormone processing; proteolysis; serine-type endopeptidase activity,PF01483;PF00082;PF16470;,,,,,,,,,PCSK7_HUMAN,Homo sapiens (Human),peptide hormone processing [GO:0016486]; protein processing [GO:0016485] comp89127_c1_seq1,403,41.9355,0.51443441,17,6,,6.00E-38,Q6NRP2,Proteasome activator complex subunit 4 (Proteasome activator PA200),Proteasome activator complex subunit 4 (Proteasome activator PA200),GO:0006281; GO:0005829; GO:0070577; GO:0016607; GO:0005634; GO:0016504; GO:0010499; GO:0035093; GO:1990111,"DNA repair; cytosol; histone acetyl-lysine binding; nuclear speck; nucleus; peptidase activator activity; proteasomal ubiquitin-independent protein catabolic process; spermatogenesis, exchange of chromosomal proteins; spermatoproteasome complex",PF16507;PF11919;,,,,,,,,,PSME4_XENLA,Xenopus laevis (African clawed frog),"cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]" comp89149_c0_seq1,219,35.1598,0.31609854,0,8,,1.00E-08,Q5SUE8,Ankyrin repeat domain-containing protein 40,Ankyrin repeat domain-containing protein 40,,,,,,,,,,,,ANR40_MOUSE,Mus musculus (Mouse), comp89153_c0_seq1,297,34.3434,1.14372299,0,29,,2.00E-11,Q9WUB9,Macrophage receptor MARCO (Macrophage receptor with collagenous structure),Macrophage receptor MARCO (Macrophage receptor with collagenous structure),GO:0005581; GO:0045087; GO:0016021; GO:0005044,collagen; innate immune response; integral to membrane; scavenger receptor activity,PF01391;PF00530;,,,,,,,,,MARCO_MESAU,Mesocricetus auratus (Golden hamster),innate immune response [GO:0045087] comp89162_c0_seq1,205,41.9512,0.33496732,0,3,,2.00E-25,A2AKB9,DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32),DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32),GO:0080008; GO:0016567,Cul4-RING ubiquitin ligase complex; protein ubiquitination,PF00400;,3.00E-15,CHOYP_RAB6B.1.1,,,,,,,DCA10_MOUSE,Mus musculus (Mouse),protein ubiquitination [GO:0016567] comp89162_c1_seq1,412,43.2039,0.575358,4,26,,2.00E-39,Q9VAT2,DDB1- and CUL4-associated factor 10 homolog (WD repeat-containing protein 32 homolog),DDB1- and CUL4-associated factor 10 homolog (WD repeat-containing protein 32 homolog),,,PF00400;,,,,,,,,,DCA10_DROME,Drosophila melanogaster (Fruit fly), comp89172_c0_seq1,874,38.2151,0.35438191,225,1012,,8.00E-56,Q7YRH6,Phosphatidylethanolamine N-methyltransferase (PEAMT) (PEMT) (EC 2.1.1.17) (EC 2.1.1.71) (PEMT2),Phosphatidylethanolamine N-methyltransferase (PEAMT) (PEMT) (EC 2.1.1.17) (EC 2.1.1.71) (PEMT2),GO:0005789; GO:0016021; GO:0031966; GO:0080101; GO:0000773; GO:0006656; GO:0004608,endoplasmic reticulum membrane; integral to membrane; mitochondrial membrane; phosphatidyl-N-dimethylethanolamine N-methyltransferase activity; phosphatidyl-N-methylethanolamine N-methyltransferase activity; phosphatidylcholine biosynthetic process; phosphatidylethanolamine N-methyltransferase activity,PF04191;,,,,,,,,,PEMT_BOVIN,Bos taurus (Bovine),phosphatidylcholine biosynthetic process [GO:0006656] comp89201_c0_seq1,244,40.1639,0.51042524,7,7,,4.00E-13,Q0D2D2,F-box only protein 31,F-box only protein 31,GO:0019005; GO:0031146; GO:0008054; GO:0031571; GO:0016567,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cyclin catabolic process; mitotic G1 DNA damage checkpoint; protein ubiquitination,PF12937;,,,,,,,,,FBX31_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cellular response to DNA damage stimulus [GO:0006974]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp89219_c0_seq1,371,46.9003,0.44951991,12,17,,1.00E-20,Q924H5,DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2),DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2),GO:0005524; GO:0003677; GO:0006281; GO:0008094; GO:0048476; GO:0008821; GO:0007066; GO:0007141; GO:0005739; GO:0005634; GO:0048471; GO:0007131; GO:0007283,ATP binding; DNA binding; DNA repair; DNA-dependent ATPase activity; Holliday junction resolvase complex; crossover junction endodeoxyribonuclease activity; female meiosis sister chromatid cohesion; male meiosis I; mitochondrion; nucleus; perinuclear region of cytoplasm; reciprocal meiotic recombination; spermatogenesis,PF08423;,,,,,,,,,RA51C_MOUSE,Mus musculus (Mouse),DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722] comp89225_c0_seq1,222,37.8378,0.13250417,9,0,,9.00E-10,P10746,Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase),Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase),GO:0071418; GO:0071243; GO:0048037; GO:0005829; GO:0006783; GO:0005739; GO:0006782; GO:0046677; GO:0006780; GO:0004852,cellular response to amine stimulus; cellular response to arsenic-containing substance; cofactor binding; cytosol; heme biosynthetic process; mitochondrion; protoporphyrinogen IX biosynthetic process; response to antibiotic; uroporphyrinogen III biosynthetic process; uroporphyrinogen-III synthase activity,PF02602;,,,,,,,,,HEM4_HUMAN,Homo sapiens (Human),cellular response to amine stimulus [GO:0071418]; cellular response to arsenic-containing substance [GO:0071243]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to antibiotic [GO:0046677]; uroporphyrinogen III biosynthetic process [GO:0006780] comp89226_c0_seq1,237,64.557,0.96544929,0,8,,7.00E-18,Q48935,Acetylpolyamine aminohydrolase,Acetylpolyamine aminohydrolase,GO:0016787; GO:0046872,hydrolase activity; metal ion binding,PF00850;,,,,,,,,,APHA_MYCRA,Mycoplana ramosa (Mycoplana bullata), comp89232_c0_seq1,319,42.3197,0.49188011,11,1,,9.00E-43,Q5MB13,ATP-binding cassette sub-family G member 2 (Urate exporter) (CD antigen CD338),ATP-binding cassette sub-family G member 2 (Urate exporter) (CD antigen CD338),GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; plasma membrane; transport,PF01061;PF00005;,2.00E-39,CHOYP_ABCG2.1.1,,,,,,,ABCG2_MACMU,Macaca mulatta (Rhesus macaque),drug transmembrane transport [GO:0006855] comp89233_c0_seq2,235,25.9574,0.76294485,5,1,,1.00E-09,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,6.00E-11,CHOYP_LOC100562878.2.2,5.00E-23,ruditapes_c19911,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp89234_c0_seq1,343,45.1895,0.28782038,0,23,,1.00E-09,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp89237_c0_seq1,247,49.7976,0.7213233,2,11,,1.00E-37,Q9JIL5,Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4),GO:0005737; GO:0035556; GO:0016567,cytoplasm; intracellular signal transduction; protein ubiquitination,PF07525;PF01167;,1.00E-45,CHOYP_DPSE_GA18988.1.1,,,,,,,TULP4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567] comp89243_c0_seq1,463,64.1469,1.11549101,0,42,,2.00E-07,Q9LBQ3,Ribulokinase (EC 2.7.1.16),Ribulokinase (EC 2.7.1.16),GO:0005524; GO:0019569; GO:0008741,ATP binding; L-arabinose catabolic process to xylulose 5-phosphate; ribulokinase activity,PF02782;PF00370;,,,,,,,,,ARAB_MYCSM,Mycobacterium smegmatis,L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569] comp89258_c1_seq1,389,47.8149,0.91037016,8,11,,3.00E-06,Q8WZ42,Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14),GO:0005524; GO:0005794; GO:0031430; GO:0030018; GO:0051015; GO:0042805; GO:0007512; GO:0005509; GO:0005516; GO:0060048; GO:0048739; GO:0003300; GO:0055008; GO:0055003; GO:0000794; GO:0005829; GO:0035995; GO:0005576; GO:0043056; GO:0001701; GO:0007076; GO:0030049; GO:0018108; GO:0030168; GO:0002576; GO:0043621; GO:0004674; GO:0004713; GO:0045859; GO:0051592; GO:0045214; GO:0048769; GO:0030241; GO:0030240; GO:0005865; GO:0008307; GO:0097493; GO:0031433,ATP binding; Golgi apparatus; M band; Z disc; actin filament binding; actinin binding; adult heart development; calcium ion binding; calmodulin binding; cardiac muscle contraction; cardiac muscle fiber development; cardiac muscle hypertrophy; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; condensed nuclear chromosome; cytosol; detection of muscle stretch; extracellular region; forward locomotion; in utero embryonic development; mitotic chromosome condensation; muscle filament sliding; peptidyl-tyrosine phosphorylation; platelet activation; platelet degranulation; protein self-association; protein serine/threonine kinase activity; protein tyrosine kinase activity; regulation of protein kinase activity; response to calcium ion; sarcomere organization; sarcomerogenesis; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle thin filament; structural constituent of muscle; structural molecule activity conferring elasticity; telethonin binding,PF00041;PF07679;PF00069;PF02818;PF09042;,,,,,,,,,TITIN_HUMAN,Homo sapiens (Human),cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] comp89310_c0_seq1,218,71.5596,1.2632105,0,15,,2.00E-06,P44093,Uncharacterized protein HI_1011,Uncharacterized protein HI_1011,,,PF17042;PF07005;,,,,,,,,,Y1011_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp89319_c0_seq1,468,45.7265,0.54632866,12,17,,3.00E-06,A4IH88,Uncharacterized protein KIAA2013 homolog,Uncharacterized protein KIAA2013 homolog,GO:0016021,integral to membrane,PF10222;,,,,,,,,,K2013_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp89325_c0_seq1,262,47.3282,0.35321492,13,0,,2.00E-06,Q9BXW9,Fanconi anemia group D2 protein (Protein FACD2),Fanconi anemia group D2 protein (Protein FACD2),GO:0006281; GO:0000793; GO:0007276; GO:0005654; GO:0010332; GO:0007129,DNA repair; condensed chromosome; gamete generation; nucleoplasm; response to gamma radiation; synapsis,PF14631;,4.00E-14,CHOYP_BRAFLDRAFT_216683.1.1,,,,,,,FACD2_HUMAN,Homo sapiens (Human),gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129] comp89336_c0_seq1,713,47.1248,0.82364978,6,29,,1.00E-38,P83851,Inosine-uridine preferring nucleoside hydrolase (IU-NH) (IU-nucleoside hydrolase) (EC 3.2.2.-) (Non-specific nucleoside hydrolase) (Purine nucleosidase),Inosine-uridine preferring nucleoside hydrolase (IU-NH) (IU-nucleoside hydrolase) (EC 3.2.2.-) (Non-specific nucleoside hydrolase) (Purine nucleosidase),GO:0005509; GO:0047724; GO:0009117; GO:0043101; GO:0045437,calcium ion binding; inosine nucleosidase activity; nucleotide metabolic process; purine-containing compound salvage; uridine nucleosidase activity,PF01156;,,,,,,,,,IUNH_LEIMA,Leishmania major,nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101] comp89340_c0_seq1,503,48.5089,1.18588704,26,0,,,,,,,,,,,1.00E-15,ruditapes_lrc34931,,,,,,, comp89359_c1_seq1,268,48.1343,0.32488375,3,12,,8.00E-15,Q5EA43,Sideroflexin-2,Sideroflexin-2,GO:0008324; GO:0016021; GO:0055072; GO:0005743,cation transmembrane transporter activity; integral to membrane; iron ion homeostasis; mitochondrial inner membrane,PF03820;,2.00E-19,CHOYP_LOC100113883.1.1,,,,,,,SFXN2_BOVIN,Bos taurus (Bovine),iron ion homeostasis [GO:0055072] comp89365_c0_seq1,367,44.6866,0.49322779,11,11,,2.00E-48,Q8IV61,Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1),Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1),GO:0000165; GO:0046582; GO:0005088; GO:0007265; GO:0005509; GO:0019992; GO:0005085; GO:0032045; GO:0005887; GO:0048471; GO:0004871; GO:0007264,MAPK cascade; Rap GTPase activator activity; Ras guanyl-nucleotide exchange factor activity; Ras protein signal transduction; calcium ion binding; diacylglycerol binding; guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor complex; integral to plasma membrane; perinuclear region of cytoplasm; signal transducer activity; small GTPase mediated signal transduction,PF00130;PF13202;PF00617;,3.00E-81,CHOYP_LOC100889329.1.1,,,,,,,GRP3_HUMAN,Homo sapiens (Human),MAPK cascade [GO:0000165]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] comp89366_c1_seq1,349,38.6819,0.46522314,8,4,,3.00E-39,Q7T163,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0016021; GO:0005770; GO:0007399,integral to membrane; late endosome; nervous system development,PF00023;PF12796;PF07693;,,,,,,,,,KDIS_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859] comp89376_c0_seq1,399,36.0902,0.30864391,0,5,,3.00E-15,Q9H2I8,Leucine-rich repeat-containing protein C10orf11,Leucine-rich repeat-containing protein C10orf11,GO:0030318,melanocyte differentiation,,6.00E-14,CHOYP_CAOG_00801.2.2,,,,,,,CJ011_HUMAN,Homo sapiens (Human),melanocyte differentiation [GO:0030318] comp89376_c0_seq2,450,36.6667,0.46770601,6,11,,5.00E-26,Q9D9B4,Leucine-rich repeat-containing protein C10orf11 homolog,Leucine-rich repeat-containing protein C10orf11 homolog,GO:0030318,melanocyte differentiation,,7.00E-14,CHOYP_CAOG_00801.1.2,,,,,,,CJ011_MOUSE,Mus musculus (Mouse),melanocyte differentiation [GO:0030318] comp89399_c0_seq1,541,42.8835,1.05859737,3,52,,4.00E-49,P55202,Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),GO:0005524; GO:0005525; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0001503; GO:0004672; GO:0006950,ATP binding; GTP binding; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; ossification; protein kinase activity; response to stress,PF01094;PF00211;PF07714;,3.00E-14,CHOYP_ANPRB.2.2,,,,,,,ANPRB_ANGJA,Anguilla japonica (Japanese eel),intracellular signal transduction [GO:0035556]; ossification [GO:0001503] comp89406_c0_seq1,446,36.9955,0.2655196,11,17,,4.00E-12,Q17QS1,Sorting nexin-24,Sorting nexin-24,GO:0007154; GO:0030659; GO:0035091; GO:0015031,cell communication; cytoplasmic vesicle membrane; phosphatidylinositol binding; protein transport,PF00787;,,,,,,,,,SNX24_BOVIN,Bos taurus (Bovine),protein transport [GO:0015031] comp89412_c0_seq1,720,41.25,0.49451399,28,19,,3.00E-11,Q5RCN7,Major facilitator superfamily domain-containing protein 4,Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4),GO:0016021; GO:0055085,integral to membrane; transmembrane transport,PF07690;,,,,,,,,,MFSD4_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),transmembrane transport [GO:0055085] comp89432_c0_seq1,1143,46.9816,0.44487687,54,18,,1.00E-128,Q8QFV0,Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit),GO:0015269; GO:0005249; GO:0008076,calcium-activated potassium channel activity; voltage-gated potassium channel activity; voltage-gated potassium channel complex,PF03493;PF07885;,9.00E-151,CHOYP_LOC655919.1.1,,,,,,,KCNT1_CHICK,Gallus gallus (Chicken), comp89443_c0_seq1,357,43.6975,0.71032303,8,18,,4.00E-39,Q8CFD4,Sorting nexin-8,Sorting nexin-8,GO:0007154; GO:0031901; GO:0034498; GO:0006886; GO:0035091; GO:0030904,cell communication; early endosome membrane; early endosome to Golgi transport; intracellular protein transport; phosphatidylinositol binding; retromer complex,PF00787;,4.00E-41,CHOYP_LOC575600.1.1,,,,,,,SNX8_MOUSE,Mus musculus (Mouse),early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] comp89443_c1_seq1,230,42.6087,0.4812591,3,4,,7.00E-22,Q8CFD4,Sorting nexin-8,Sorting nexin-8,GO:0007154; GO:0031901; GO:0034498; GO:0006886; GO:0035091; GO:0030904,cell communication; early endosome membrane; early endosome to Golgi transport; intracellular protein transport; phosphatidylinositol binding; retromer complex,PF00787;,,,,,,,,,SNX8_MOUSE,Mus musculus (Mouse),early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] comp89447_c0_seq1,278,39.9281,0.3647106,8,7,,4.00E-31,Q9D4H8,Cullin-2 (CUL-2),Cullin-2 (CUL-2),GO:0031462; GO:0030163; GO:0016567; GO:0006511,Cul2-RING ubiquitin ligase complex; protein catabolic process; protein ubiquitination; ubiquitin-dependent protein catabolic process,PF00888;PF10557;,9.00E-29,CHOYP_CUL2.1.1,,,,,,,CUL2_MOUSE,Mus musculus (Mouse),protein catabolic process [GO:0030163]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp89476_c0_seq1,483,43.2712,0.45191604,11,1,,9.00E-07,Q9ULI1,Leucine-rich repeat and WD repeat-containing protein KIAA1239,NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239),,,PF13271;,,,,,,,,,K1239_HUMAN,Homo sapiens (Human), comp89476_c1_seq1,206,43.2039,0.32044099,6,0,,4.00E-07,Q99973,Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog),GO:0005524; GO:0003723; GO:0000781; GO:0005737; GO:0016363; GO:0005697; GO:0000722,"ATP binding; RNA binding; chromosome, telomeric region; cytoplasm; nuclear matrix; telomerase holoenzyme complex; telomere maintenance via recombination",PF13271;PF05386;PF05731;PF00400;,,,,,,,,,TEP1_HUMAN,Homo sapiens (Human),telomere maintenance via recombination [GO:0000722] comp89479_c0_seq1,337,41.2463,0.35135445,6,13,,1.00E-18,P35822,Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48),GO:0030424; GO:0030425; GO:0016021; GO:0043025; GO:0001750; GO:0004725,axon; dendrite; integral to membrane; neuronal cell body; photoreceptor outer segment; protein tyrosine phosphatase activity,PF00041;PF07679;PF00629;PF00102;,,,,,,,,,PTPRK_MOUSE,Mus musculus (Mouse),"cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]" comp89508_c0_seq2,301,42.8571,0.50817869,2,7,,4.00E-29,Q6PBY7,Trafficking protein particle complex subunit 13,Trafficking protein particle complex subunit 13,,,PF06159;,4.00E-21,CHOYP_BRAFLDRAFT_282065.2.2,,,,,,,CE044_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp89549_c0_seq1,246,41.8699,1.05311818,0,21,,5.00E-12,Q80TS8,Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3),Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3),GO:0016021,integral to membrane,PF08238;,3.00E-15,CHOYP_BRAFLDRAFT_130493.1.1,,,,,,,SE1L3_MOUSE,Mus musculus (Mouse), comp89556_c0_seq1,692,40.896,0.70707218,72,410,,2.00E-23,P41437,E3 ubiquitin-protein ligase IAP-3 (EC 6.3.2.-) (IAP-3),E3 ubiquitin-protein ligase IAP-3 (EC 6.3.2.-) (IAP-3),GO:0006915; GO:0016874; GO:0039648; GO:0008270,apoptotic process; ligase activity; modulation by virus of host protein ubiquitination; zinc ion binding,PF00653;,1.00E-12,CHOYP_BIRC7.2.5,,,,,,,IAP3_NPVOP,Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV),modulation by virus of host protein ubiquitination [GO:0039648] comp89561_c0_seq2,454,44.2731,1.01521791,0,16,,2.00E-25,Q75A26,ADP-ribosylation factor,ADP-ribosylation factor,GO:0006888; GO:0005525; GO:0005794; GO:0006893; GO:0016236; GO:0015031; GO:0007264,ER to Golgi vesicle-mediated transport; GTP binding; Golgi apparatus; Golgi to plasma membrane transport; macroautophagy; protein transport; small GTPase mediated signal transduction,PF00025;,,,,,,,,,ARF_ASHGO,Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii),protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] comp89567_c0_seq1,279,44.8029,1.36622197,12,8,,4.00E-19,Q8JIS3,D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10),GO:0042732; GO:0050038; GO:0005737; GO:0047880,D-xylose metabolic process; L-xylulose reductase (NADP+) activity; cytoplasm; erythrulose reductase activity,,,,,,,,,,DER_CHICK,Gallus gallus (Chicken),D-xylose metabolic process [GO:0042732] comp89596_c0_seq1,250,44,0,55,10,,,,,,,,,7.00E-11,CHOYP_contig_010754,,,,,,,,, comp89596_c0_seq2,227,43.1718,0,27,1,,,,,,,,,6.00E-11,CHOYP_contig_030401,,,,,,,,, comp89597_c1_seq1,1083,41.5512,0.90881585,38,46,,3.00E-15,Q9VZW5,FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor),FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor),GO:0002209; GO:0007204; GO:0005887; GO:0008345; GO:0008188,behavioral defense response; elevation of cytosolic calcium ion concentration; integral to plasma membrane; larval locomotory behavior; neuropeptide receptor activity,PF10324;,9.00E-30,CHOYP_CRE_21950.1.1,,,,,,,FMAR_DROME,Drosophila melanogaster (Fruit fly),adult locomotory behavior [GO:0008344]; behavioral defense response [GO:0002209]; G-protein coupled receptor signaling pathway [GO:0007186]; larval locomotory behavior [GO:0008345]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration [GO:0007204] comp89610_c0_seq1,567,35.6261,0.50157142,627,2297,,1.00E-18,Q5M8Z2,"Protein preY, mitochondrial","Protein preY, mitochondrial",GO:0005739,mitochondrion,PF03966;,,,3.00E-24,ruditapes_c23202,,,,,PREY_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp89623_c0_seq2,339,48.3776,0.81340421,0,0,,6.00E-22,Q7Z3S7,Voltage-dependent calcium channel subunit alpha-2/delta-4 (Voltage-gated calcium channel subunit alpha-2/delta-4) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4],Voltage-dependent calcium channel subunit alpha-2/delta-4 (Voltage-gated calcium channel subunit alpha-2/delta-4) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4],GO:0005262; GO:0016021; GO:0046872; GO:0005244,calcium channel activity; integral to membrane; metal ion binding; voltage-gated ion channel activity,PF08473;PF13768;PF08399;,3.00E-24,CHOYP_NEMVEDRAFT_V1G240929.1.1,,,,,,,CA2D4_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; cardiac conduction [GO:0061337]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924] comp89624_c0_seq1,438,44.7489,0.82355823,2,13,,8.00E-11,P35236,Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) (Protein-tyrosine phosphatase LC-PTP),Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) (Protein-tyrosine phosphatase LC-PTP),GO:0005856; GO:0005829; GO:0009898; GO:0004725,cytoskeleton; cytosol; internal side of plasma membrane; protein tyrosine phosphatase activity,PF00102;,,,,,,,,,PTN7_HUMAN,Homo sapiens (Human),protein dephosphorylation [GO:0006470] comp89659_c0_seq1,208,43.75,1.21514437,23,0,,,,,,,,,1.00E-13,CHOYP_LOC101076707.1.1,,,,,,,,, comp89664_c0_seq1,3887,40.8541,0.29750361,1377,6022,,2.00E-45,Q7TPD6,Ribonucleoprotein PTB-binding 2 (Protein raver-2),Ribonucleoprotein PTB-binding 2 (Protein raver-2),GO:0003723; GO:0005737; GO:0000166; GO:0005634,RNA binding; cytoplasm; nucleotide binding; nucleus,PF00076;,,,,,,,,,RAVR2_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]" comp89678_c1_seq2,330,44.8485,0.48676918,2,8,,8.00E-12,Q5CZL1,Ganglioside-induced differentiation-associated protein 2,Ganglioside-induced differentiation-associated protein 2,,,PF13716;PF01661;,,,,,,,,,GDAP2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp89699_c0_seq1,713,45.3015,0.27375255,26,10,,6.00E-39,A2VCL2,Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene),Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene),,,,1.00E-38,CHOYP_LOC579367.1.1,,,,,,,CC162_HUMAN,Homo sapiens (Human), comp89707_c0_seq1,329,42.5532,0.67846022,1,14,,1.00E-11,Q90687,Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2),Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2),GO:0000077; GO:0038127; GO:0000187; GO:0036302; GO:0007409; GO:0007420; GO:0005737; GO:0048013; GO:0060325; GO:0048806; GO:0042593; GO:0042445; GO:0009755; GO:0048839; GO:0048609; GO:0051463; GO:0060125; GO:0046676; GO:0048011; GO:0004726; GO:0005634; GO:0035265; GO:2001275; GO:0046887; GO:0033628; GO:0040014; GO:0046825; GO:0006641,DNA damage checkpoint; ERBB signaling pathway; activation of MAPK activity; atrioventricular canal development; axonogenesis; brain development; cytoplasm; ephrin receptor signaling pathway; face morphogenesis; genitalia development; glucose homeostasis; hormone metabolic process; hormone-mediated signaling pathway; inner ear development; multicellular organismal reproductive process; negative regulation of cortisol secretion; negative regulation of growth hormone secretion; negative regulation of insulin secretion; neurotrophin TRK receptor signaling pathway; non-membrane spanning protein tyrosine phosphatase activity; nucleus; organ growth; positive regulation of glucose import in response to insulin stimulus; positive regulation of hormone secretion; regulation of cell adhesion mediated by integrin; regulation of multicellular organism growth; regulation of protein export from nucleus; triglyceride metabolic process,PF00017;PF00102;,,,,,,,,,PTN11_CHICK,Gallus gallus (Chicken),abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; face morphogenesis [GO:0060325]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of hormone secretion [GO:0046887]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of multicellular organism growth [GO:0040014]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; triglyceride metabolic process [GO:0006641] comp89709_c0_seq1,290,46.2069,0.68746388,6,0,,2.00E-14,P12080,Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain],Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain],GO:0016324; GO:0007475; GO:0007411; GO:0007414; GO:0009925; GO:0007298; GO:0050839; GO:0007160; GO:0007427; GO:0035099; GO:0007157; GO:0008305; GO:0007229; GO:0016328; GO:0035160; GO:0045185; GO:0007494; GO:0016203; GO:0030239; GO:0004872; GO:0008360; GO:0051492; GO:0007435; GO:0042383; GO:0007608; GO:0007426,"apical plasma membrane; apposition of dorsal and ventral imaginal disc-derived wing surfaces; axon guidance; axonal defasciculation; basal plasma membrane; border follicle cell migration; cell adhesion molecule binding; cell-matrix adhesion; epithelial cell migration, open tracheal system; hemocyte migration; heterophilic cell-cell adhesion; integrin complex; integrin-mediated signaling pathway; lateral plasma membrane; maintenance of epithelial integrity, open tracheal system; maintenance of protein location; midgut development; muscle attachment; myofibril assembly; receptor activity; regulation of cell shape; regulation of stress fiber assembly; salivary gland morphogenesis; sarcolemma; sensory perception of smell; tracheal outgrowth, open tracheal system",PF01839;PF00357;PF08441;,,,,,,,,,ITA2_DROME,Drosophila melanogaster (Fruit fly),"apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; epithelial cell migration, open tracheal system [GO:0007427]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; maintenance of protein location [GO:0045185]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; myofibril assembly [GO:0030239]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]" comp89717_c0_seq1,250,40,0.50281253,4,0,,3.00E-15,P51691,Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase),Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase),GO:0004065; GO:0044248; GO:0005737; GO:0046872,arylsulfatase activity; cellular catabolic process; cytoplasm; metal ion binding,PF00884;,,,,,,,,,ARS_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),metabolic process [GO:0008152] comp89717_c2_seq1,281,47.331,0.44641,7,1,,8.00E-38,Q8BM89,Arylsulfatase J (ASJ) (EC 3.1.6.-),Arylsulfatase J (ASJ) (EC 3.1.6.-),GO:0005576; GO:0046872; GO:0008484,extracellular region; metal ion binding; sulfuric ester hydrolase activity,PF00884;,1.00E-53,CHOYP_LOC100377677.1.2,,,,,,,ARSJ_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp89728_c0_seq1,316,41.1392,0.45710624,8,12,,4.00E-26,Q96L93,Kinesin-like protein KIF16B (Sorting nexin-23),Kinesin-like protein KIF16B (Sorting nexin-23),GO:0005524; GO:0006895; GO:0005769; GO:0031901; GO:0045022; GO:0007492; GO:0007173; GO:0008543; GO:0001704; GO:0005871; GO:0005874; GO:0007018; GO:0005547; GO:0043325; GO:0080025; GO:0032266; GO:0008574; GO:0032801; GO:0001919,"ATP binding; Golgi to endosome transport; early endosome; early endosome membrane; early endosome to late endosome transport; endoderm development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; formation of primary germ layer; kinesin complex; microtubule; microtubule-based movement; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; plus-end-directed microtubule motor activity; receptor catabolic process; regulation of receptor recycling",PF00498;PF00225;PF00787;,,,,,,,,,KI16B_HUMAN,Homo sapiens (Human),cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] comp89734_c0_seq1,533,45.2158,0.99917192,13,0,,3.00E-16,Q8NFZ3,"Neuroligin-4, Y-linked (Neuroligin Y)","Neuroligin-4, Y-linked (Neuroligin Y)",GO:0007155; GO:0030054; GO:0009986; GO:0005887; GO:0042043; GO:0014069; GO:0045211; GO:0004872; GO:0045202; GO:0007416,cell adhesion; cell junction; cell surface; integral to plasma membrane; neurexin family protein binding; postsynaptic density; postsynaptic membrane; receptor activity; synapse; synapse assembly,PF00135;,,,,,,,,,NLGNY_HUMAN,Homo sapiens (Human),learning [GO:0007612]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625] comp89734_c0_seq2,426,45.0704,1.02476838,0,0,,6.00E-06,Q64419,Liver carboxylesterase (EC 3.1.1.1),Liver carboxylesterase (EC 3.1.1.1),GO:0004091; GO:0005788,carboxylesterase activity; endoplasmic reticulum lumen,PF00135;,,,,,,,,,EST1_MESAU,Mesocricetus auratus (Golden hamster), comp89747_c1_seq1,475,43.3684,0.49354541,22,0,,2.00E-11,Q6V0I7,Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF07645;PF02210;,,,,,,,,,FAT4_HUMAN,Homo sapiens (Human),branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] comp89754_c0_seq1,795,48.6792,0.25515587,48,15,,8.00E-13,P41437,E3 ubiquitin-protein ligase IAP-3 (EC 6.3.2.-) (IAP-3),E3 ubiquitin-protein ligase IAP-3 (EC 6.3.2.-) (IAP-3),GO:0006915; GO:0016874; GO:0039648; GO:0008270,apoptotic process; ligase activity; modulation by virus of host protein ubiquitination; zinc ion binding,PF00653;,,,,,,,,,IAP3_NPVOP,Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV),modulation by virus of host protein ubiquitination [GO:0039648] comp8976_c0_seq1,339,44.2478,0.54487654,6,0,,6.00E-33,Q14CM0,FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso),FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso),GO:0005856; GO:0043197; GO:0005546; GO:0051835,"cytoskeleton; dendritic spine; phosphatidylinositol-4,5-bisphosphate binding; positive regulation of synapse structural plasticity",PF00373;PF00595;,5.00E-33,CHOYP_BRAFLDRAFT_63883.1.1,,,,,,,FRPD4_HUMAN,Homo sapiens (Human),positive regulation of synapse structural plasticity [GO:0051835] comp89802_c0_seq1,482,46.6805,0.49896909,7,40,,5.00E-22,Q96N96,Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2),Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2),GO:0030676; GO:0016477; GO:0005737; GO:0030175; GO:0046847; GO:0030027; GO:0030032; GO:0005634; GO:0005543; GO:0035023; GO:0030334; GO:0032587,Rac guanyl-nucleotide exchange factor activity; cell migration; cytoplasm; filopodium; filopodium assembly; lamellipodium; lamellipodium assembly; nucleus; phospholipid binding; regulation of Rho protein signal transduction; regulation of cell migration; ruffle membrane,PF00169;PF00621;PF00018;,3.00E-45,CHOYP_ISCW_ISCW011606.2.2,,,,,,,SPT13_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; regulation of cell migration [GO:0030334]; regulation of Rho protein signal transduction [GO:0035023] comp89812_c0_seq1,571,40.9807,0.89876819,196,1539,,,,,,,,,9.00E-14,CHOYP_TAGL3.1.1,2.00E-27,ruditapes_lrc33479,,,,,,, comp89826_c0_seq1,376,40.4255,0.26126311,8,15,,1.00E-07,Q7Z118,Putative transporter B0361.11,Putative transporter B0361.11,GO:0008643; GO:0016021; GO:0022857,carbohydrate transport; integral to membrane; transmembrane transporter activity,PF00083;,,,,,,,,,YMPB_CAEEL,Caenorhabditis elegans,carbohydrate transport [GO:0008643] comp89826_c1_seq1,529,40.8318,0.45630813,12,66,,1.00E-35,Q9VCA2,Organic cation transporter protein,Organic cation transporter protein,GO:0006915; GO:0016021; GO:0006811; GO:0022857,apoptotic process; integral to membrane; ion transport; transmembrane transporter activity,PF00083;,,,,,,,,,ORCT_DROME,Drosophila melanogaster (Fruit fly),apoptotic process [GO:0006915]; ion transport [GO:0006811] comp89842_c0_seq1,216,68.5185,1.19430188,0,25,,1.00E-07,P21362,Protein YciF,Protein YciF,GO:0006974,response to DNA damage stimulus,PF05974;,,,,,,,,,YCIF_ECOLI,Escherichia coli (strain K12),cellular response to DNA damage stimulus [GO:0006974] comp89855_c0_seq1,255,62.3529,0.89284823,0,8,,3.00E-22,P77894,Probable copper-exporting P-type ATPase V (EC 3.6.3.54) (Cu(+)-exporting ATPase),,GO:0005524; GO:0019829; GO:0005618; GO:0006825; GO:0005887; GO:0046872; GO:0009405; GO:0046688; GO:0052572,ATP binding; cation-transporting ATPase activity; cell wall; copper ion transport; integral to plasma membrane; metal ion binding; pathogenesis; response to copper ion; response to host immune response,,,,,,,,,,CTPV_MYCTU,, comp89857_c0_seq1,597,41.0385,0.28188631,25,12,,,,,,,,,4.00E-12,CHOYP_BRAFLDRAFT_118099.3.6,,,,,,,,, comp89879_c0_seq1,225,45.7778,0.17082726,0,4,,2.00E-16,Q94BV5,Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4),Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4),GO:0004499; GO:0050661; GO:0050660; GO:0005773,"N,N-dimethylaniline monooxygenase activity; NADP binding; flavin adenine dinucleotide binding; vacuole",PF00743;,1.00E-14,CHOYP_BRAFLDRAFT_278918.2.5,,,,,,,GSXL4_ARATH,Arabidopsis thaliana (Mouse-ear cress),oxidation-reduction process [GO:0055114] comp89879_c0_seq2,234,44.4444,0.17440022,0,3,,4.00E-12,Q9FLK4,Flavin-containing monooxygenase FMO GS-OX-like 8 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 8),Flavin-containing monooxygenase FMO GS-OX-like 8 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 8),GO:0004499; GO:0050661; GO:0050660,"N,N-dimethylaniline monooxygenase activity; NADP binding; flavin adenine dinucleotide binding",PF00743;,,,,,,,,,GSXL8_ARATH,Arabidopsis thaliana (Mouse-ear cress),oxidation-reduction process [GO:0055114] comp89897_c0_seq1,221,44.7964,0.54501934,0,18,,5.00E-14,Q8BPM0,Disheveled-associated activator of morphogenesis 1,Disheveled-associated activator of morphogenesis 1,GO:0030036; GO:0005737; GO:0005886; GO:0001725,actin cytoskeleton organization; cytoplasm; plasma membrane; stress fiber,PF06367;PF06371;PF02181;,2.00E-35,CHOYP_LOC658864.1.1,,,,,,,DAAM1_MOUSE,Mus musculus (Mouse),actin cytoskeleton organization [GO:0030036] comp89905_c0_seq1,210,38.0952,0.40813305,0,7,,3.00E-16,Q96IZ5,RNA-binding protein 41 (RNA-binding motif protein 41),RNA-binding protein 41 (RNA-binding motif protein 41),GO:0003723; GO:0000166,RNA binding; nucleotide binding,PF00076;,,,,,,,,,RBM41_HUMAN,Homo sapiens (Human),"developmental process [GO:0032502]; mRNA splicing, via spliceosome [GO:0000398]" comp89909_c0_seq1,335,47.4627,0.15949509,18,2,,7.00E-23,Q95216,Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (RUSH-1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (RUSH-1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3),GO:0005524; GO:0003677; GO:0016568; GO:0005737; GO:0004386; GO:0016874; GO:0005730; GO:0005654; GO:0016567; GO:0006351; GO:0008270,"ATP binding; DNA binding; chromatin modification; cytoplasm; helicase activity; ligase activity; nucleolus; nucleoplasm; protein ubiquitination; transcription, DNA-dependent; zinc ion binding",PF00271;PF08797;PF00176;PF00097;,,,,,,,,,HLTF_RABIT,Oryctolagus cuniculus (Rabbit),"chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]" comp89920_c0_seq1,255,52.9412,0.86655104,3,5,,3.00E-24,Q684M4,Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2),Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2),GO:0031463; GO:0005737; GO:0005634; GO:0010499; GO:0016567; GO:0006355; GO:0006351,"Cul3-RING ubiquitin ligase complex; cytoplasm; nucleus; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF07707;PF00651;PF01344;,6.00E-37,CHOYP_KEAP1.1.1,,,,,,,KEAP1_PIG,Sus scrofa (Pig),"cytoplasmic sequestering of transcription factor [GO:0042994]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; transcription, DNA-templated [GO:0006351]" comp89926_c0_seq1,359,43.1755,0.23984197,5,13,,1.00E-27,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,1.00E-15,CHOYP_HSPA12A.16.27,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp89927_c0_seq1,483,45.1346,0.85729112,11,32,,3.00E-06,Q9NJB5,Homeobox protein onecut,Homeobox protein onecut,GO:0001077; GO:0005634; GO:0043565,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; nucleus; sequence-specific DNA binding,PF02376;PF00046;,,,,,,,,,ONEC_DROME,Drosophila melanogaster (Fruit fly),"cell differentiation [GO:0030154]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; sensory perception of pain [GO:0019233]; system development [GO:0048731]" comp89927_c1_seq1,488,44.877,0.58115694,0,5,,5.00E-49,Q6XBJ3,One cut domain family member 2 (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2),One cut domain family member 2 (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2),GO:0003677; GO:0045165; GO:0042384; GO:0031018; GO:0002064; GO:0001889; GO:0030512; GO:0005634; GO:0048935; GO:0030335; GO:0045944; GO:0001952; GO:0043565; GO:0003700; GO:0006351,"DNA binding; cell fate commitment; cilium assembly; endocrine pancreas development; epithelial cell development; liver development; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; peripheral nervous system neuron development; positive regulation of cell migration; positive regulation of transcription from RNA polymerase II promoter; regulation of cell-matrix adhesion; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02376;PF00046;,,,,,,,,,ONEC2_MOUSE,Mus musculus (Mouse),anatomical structure morphogenesis [GO:0009653]; cell fate commitment [GO:0045165]; cilium assembly [GO:0042384]; endocrine pancreas development [GO:0031018]; epithelial cell development [GO:0002064]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; pancreas development [GO:0031016]; peripheral nervous system neuron development [GO:0048935]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952] comp89927_c1_seq2,509,44.9902,0.55229174,4,0,,4.00E-50,O08755,Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1),Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1),GO:0030183; GO:0003677; GO:0045165; GO:0042384; GO:0031018; GO:0007492; GO:0002064; GO:0006006; GO:0001889; GO:0030512; GO:0005654; GO:0030335; GO:0045944; GO:0001952; GO:0043565; GO:0003700; GO:0048536; GO:0006351,"B cell differentiation; DNA binding; cell fate commitment; cilium assembly; endocrine pancreas development; endoderm development; epithelial cell development; glucose metabolic process; liver development; negative regulation of transforming growth factor beta receptor signaling pathway; nucleoplasm; positive regulation of cell migration; positive regulation of transcription from RNA polymerase II promoter; regulation of cell-matrix adhesion; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; spleen development; transcription, DNA-dependent",PF02376;PF00046;,9.00E-58,CHOYP_ONEC2.1.3,,,,,,,HNF6_MOUSE,Mus musculus (Mouse),anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cilium assembly [GO:0042384]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; epithelial cell development [GO:0002064]; glucose metabolic process [GO:0006006]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spleen development [GO:0048536] comp89946_c0_seq1,286,40.5594,0.26091228,8,12,,3.00E-25,Q9V3A6,Ero1-like protein (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein),Ero1-like protein (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductin-1-like protein),GO:0051085; GO:0005783; GO:0005789; GO:0016491; GO:0016671; GO:0003756,"chaperone mediated protein folding requiring cofactor; endoplasmic reticulum; endoplasmic reticulum membrane; oxidoreductase activity; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; protein disulfide isomerase activity",PF04137;,,,,,,,,,ERO1L_DROME,Drosophila melanogaster (Fruit fly),chaperone mediated protein folding requiring cofactor [GO:0051085] comp89969_c0_seq1,652,49.3865,0.63690069,25,14,,6.00E-32,Q495T6,"Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]","Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]",GO:0005794; GO:0005783; GO:0005615; GO:0016021; GO:0004222; GO:0006508; GO:0008270,Golgi apparatus; endoplasmic reticulum; extracellular space; integral to membrane; metalloendopeptidase activity; proteolysis; zinc ion binding,PF01431;PF05649;,2.00E-11,CHOYP_MMEL1.3.3,,,,,,,MMEL1_HUMAN,Homo sapiens (Human), comp89970_c0_seq1,262,43.5115,0.85390854,3,0,,2.00E-29,Q07E01,Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met),GO:0005524; GO:0016021; GO:0007275; GO:0018108; GO:0004714; GO:0007169,ATP binding; integral to membrane; multicellular organismal development; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway,PF07714;PF01403;PF01833;,2.00E-30,CHOYP_BRAFLDRAFT_118213.2.2,,,,,,,MET_ORNAN,Ornithorhynchus anatinus (Duckbill platypus),positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] comp89974_c0_seq1,353,35.9773,0.35224163,9,0,,1.00E-20,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp89978_c0_seq1,436,46.1009,0.30323316,14,4,,5.00E-07,Q86XX4,Extracellular matrix protein FRAS1,Extracellular matrix protein FRAS1,GO:0005604; GO:0007154; GO:0016021; GO:0046872; GO:0002009; GO:0005886; GO:0015031; GO:0043588,basement membrane; cell communication; integral to membrane; metal ion binding; morphogenesis of an epithelium; plasma membrane; protein transport; skin development,PF03160;PF00093;,,,,,,,,,FRAS1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588] comp89985_c0_seq1,404,40.3465,0.3658559,0,0,,9.00E-16,P13360,Protein glass,Protein glass,GO:0003677; GO:0003705; GO:0001752; GO:0043153; GO:0046872; GO:0005634; GO:0045944; GO:0010114; GO:0035271; GO:0007605; GO:0007601,DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; compound eye photoreceptor fate commitment; entrainment of circadian clock by photoperiod; metal ion binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to red light; ring gland development; sensory perception of sound; visual perception,PF00096;,,,,,,,,,GLAS_DROME,Drosophila melanogaster (Fruit fly),"circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]" comp89985_c0_seq2,508,38.7795,0.42214553,2,5,,3.00E-16,P18748,Oocyte zinc finger protein XlCOF29,Oocyte zinc finger protein XlCOF29,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZO29_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp89986_c0_seq1,412,44.1748,0.551874,8,8,,2.00E-45,P13686,Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase),GO:0003993; GO:0060349; GO:0045453; GO:0005829; GO:0050830; GO:0008199; GO:0008198; GO:0016021; GO:0005764; GO:0050728; GO:0032691; GO:0032695; GO:0045019; GO:0032929; GO:0032720; GO:0034097; GO:0032496; GO:0006771,acid phosphatase activity; bone morphogenesis; bone resorption; cytosol; defense response to Gram-positive bacterium; ferric iron binding; ferrous iron binding; integral to membrane; lysosome; negative regulation of inflammatory response; negative regulation of interleukin-1 beta production; negative regulation of interleukin-12 production; negative regulation of nitric oxide biosynthetic process; negative regulation of superoxide anion generation; negative regulation of tumor necrosis factor production; response to cytokine stimulus; response to lipopolysaccharide; riboflavin metabolic process,PF00149;,,,,,,,,,PPA5_HUMAN,Homo sapiens (Human),bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell adhesion [GO:0007162]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of cell migration [GO:0030335]; response to cholesterol [GO:0070723]; response to cytokine [GO:0034097]; response to L-ascorbic acid [GO:0033591]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; riboflavin metabolic process [GO:0006771] comp89990_c3_seq1,293,65.8703,1.25584469,0,13,,8.00E-19,Q99338,Insertion sequence IS232 putative ATP-binding protein,Insertion sequence IS232 putative ATP-binding protein,GO:0005524; GO:0017111,ATP binding; nucleoside-triphosphatase activity,PF01695;,,,,,,,,,ISTB_BACTB,Bacillus thuringiensis subsp. berliner, comp89994_c1_seq1,532,37.782,0.52772464,7,14,,6.00E-19,Q9JLC8,Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29),GO:0005524; GO:0050750; GO:0005739; GO:0090084; GO:0005634,ATP binding; low-density lipoprotein particle receptor binding; mitochondrion; negative regulation of inclusion body assembly; nucleus,PF05168;,,,,,,,,,SACS_MOUSE,Mus musculus (Mouse), comp89996_c0_seq1,874,47.0252,0.45590245,42,16,,2.00E-14,Q9NWM3,CUE domain-containing protein 1,CUE domain-containing protein 1,,,PF02845;,,,,,,,,,CUED1_HUMAN,Homo sapiens (Human), comp89999_c0_seq1,312,43.5897,0.83840147,0,18,,1.00E-26,P79371,Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),GO:0033514; GO:0050031; GO:0005777; GO:0008115; GO:0046653,L-lysine catabolic process to acetyl-CoA via L-pipecolate; L-pipecolate oxidase activity; peroxisome; sarcosine oxidase activity; tetrahydrofolate metabolic process,PF01266;,,,,,,,,,SOX_RABIT,Oryctolagus cuniculus (Rabbit),L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; oxidation-reduction process [GO:0055114]; tetrahydrofolate metabolic process [GO:0046653] comp90003_c1_seq1,515,46.9903,0.39971982,9,24,,2.00E-17,A4UTP7,Myocyte-specific enhancer factor 2C,Myocyte-specific enhancer factor 2C,GO:0001782; GO:0042100; GO:0050853; GO:0000165; GO:0001077; GO:0000983; GO:0000977; GO:0001568; GO:0001974; GO:0003211; GO:0071277; GO:0035690; GO:0071498; GO:0071222; GO:0071374; GO:0071560; GO:0035984; GO:0002062; GO:0005737; GO:0001958; GO:2001013; GO:0002467; GO:0072102; GO:0001947; GO:0006959; GO:0007611; GO:0030318; GO:0035198; GO:0007521; GO:0043524; GO:0030279; GO:0000122; GO:0072160; GO:0014033; GO:0048666; GO:0016607; GO:0001649; GO:0003151; GO:0030220; GO:0030890; GO:0010694; GO:2000987; GO:0030501; GO:2000727; GO:0060045; GO:2000111; GO:0045663; GO:0045666; GO:0045669; GO:0090073; GO:2001016; GO:0048643; GO:0003138; GO:0043234; GO:0002634; GO:0045652; GO:0060025; GO:0003139; GO:0003185; GO:0007519; GO:0051145; GO:0055012,B cell homeostasis; B cell proliferation; B cell receptor signaling pathway; MAPK cascade; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding; blood vessel development; blood vessel remodeling; cardiac ventricle formation; cellular response to calcium ion; cellular response to drug; cellular response to fluid shear stress; cellular response to lipopolysaccharide; cellular response to parathyroid hormone stimulus; cellular response to transforming growth factor beta stimulus; cellular response to trichostatin A; chondrocyte differentiation; cytoplasm; endochondral ossification; epithelial cell proliferation involved in renal tubule morphogenesis; germinal center formation; glomerulus morphogenesis; heart looping; humoral immune response; learning or memory; melanocyte differentiation; miRNA binding; muscle cell fate determination; negative regulation of neuron apoptotic process; negative regulation of ossification; negative regulation of transcription from RNA polymerase II promoter; nephron tubule epithelial cell differentiation; neural crest cell differentiation; neuron development; nuclear speck; osteoblast differentiation; outflow tract morphogenesis; platelet formation; positive regulation of B cell proliferation; positive regulation of alkaline phosphatase activity; positive regulation of behavioral fear response; positive regulation of bone mineralization; positive regulation of cardiac muscle cell differentiation; positive regulation of cardiac muscle cell proliferation; positive regulation of macrophage apoptotic process; positive regulation of myoblast differentiation; positive regulation of neuron differentiation; positive regulation of osteoblast differentiation; positive regulation of protein homodimerization activity; positive regulation of skeletal muscle cell differentiation; positive regulation of skeletal muscle tissue development; primary heart field specification; protein complex; regulation of germinal center formation; regulation of megakaryocyte differentiation; regulation of synaptic activity; secondary heart field specification; sinoatrial valve morphogenesis; skeletal muscle tissue development; smooth muscle cell differentiation; ventricular cardiac muscle cell differentiation,PF12347;PF00319;,7.00E-15,CHOYP_MEF2C.1.1,,,,,,,MEF2C_PIG,Sus scrofa (Pig),"B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012]" comp90022_c0_seq1,702,45.4416,0.37686674,18,18,,3.00E-32,Q6DI48,Delta-like protein A (DeltaA),Delta-like protein A (DeltaA),GO:0007219; GO:0001525; GO:0005509; GO:0030154; GO:0016021; GO:0007399,Notch signaling pathway; angiogenesis; calcium ion binding; cell differentiation; integral to membrane; nervous system development,PF01414;PF00008;PF07657;,,,,,,,,,DLLA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),angiogenesis [GO:0001525]; diencephalon development [GO:0021536]; embryonic pattern specification [GO:0009880]; floor plate development [GO:0033504]; hypochord development [GO:0055016]; inner ear receptor cell differentiation [GO:0060113]; midbrain development [GO:0030901]; neural crest cell development [GO:0014032]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; notochord cell differentiation [GO:0060034]; regulation of Notch signaling pathway [GO:0008593]; ventral spinal cord interneuron differentiation [GO:0021514] comp90030_c0_seq1,695,42.0144,0.2285719,27,12,,6.00E-11,Q9DER7,Tolloid-like protein 1 (EC 3.4.24.-) (Chicken tolloid-like protein 1) (Metalloprotease colloid),Tolloid-like protein 1 (EC 3.4.24.-) (Chicken tolloid-like protein 1) (Metalloprotease colloid),GO:0005509; GO:0030154; GO:0005576; GO:0004222; GO:0007275; GO:0006508; GO:0008270,calcium ion binding; cell differentiation; extracellular region; metalloendopeptidase activity; multicellular organismal development; proteolysis; zinc ion binding,PF01400;PF00431;,,,,,,,,,TLL1_CHICK,Gallus gallus (Chicken),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp90039_c0_seq1,271,47.2325,0.99830085,0,26,,4.00E-08,O08590,Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1),Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1),GO:0007568; GO:0052595; GO:0009308; GO:0052594; GO:0007155; GO:0009986; GO:0005507; GO:0042755; GO:0005615; GO:0016021; GO:0043231; GO:0002523; GO:0052596; GO:0005886; GO:0002675; GO:0010828; GO:0002687; GO:0008131; GO:0042803; GO:0048038; GO:0008217; GO:0052593,aging; aliphatic-amine oxidase activity; amine metabolic process; aminoacetone:oxygen oxidoreductase(deaminating) activity; cell adhesion; cell surface; copper ion binding; eating behavior; extracellular space; integral to membrane; intracellular membrane-bounded organelle; leukocyte migration involved in inflammatory response; phenethylamine:oxygen oxidoreductase (deaminating) activity; plasma membrane; positive regulation of acute inflammatory response; positive regulation of glucose transport; positive regulation of leukocyte migration; primary amine oxidase activity; protein homodimerization activity; quinone binding; regulation of blood pressure; tryptamine:oxygen oxidoreductase (deaminating) activity,PF01179;PF02727;PF02728;,,,,,,,,,AOC3_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]; eating behavior [GO:0042755]; leukocyte migration involved in inflammatory response [GO:0002523]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of glucose transport [GO:0010828]; positive regulation of leukocyte migration [GO:0002687]; regulation of blood pressure [GO:0008217]; response to immobilization stress [GO:0035902] comp90048_c0_seq1,659,33.2322,1.26626918,18,21,,3.00E-18,Q8N7M0,Tctex1 domain-containing protein 1,Tctex1 domain-containing protein 1,,,PF03645;,,,,,,,,,TC1D1_HUMAN,Homo sapiens (Human), comp90050_c0_seq1,579,37.9965,0.8181918,19,12,,8.00E-06,Q9HAZ2,PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1),GO:0050873; GO:0046872; GO:0030853; GO:0000122; GO:0030512; GO:0022008; GO:0060021; GO:0045893; GO:0043457; GO:0043565; GO:0035019; GO:0043586; GO:0003713; GO:0006351; GO:0017053; GO:0050872,"brown fat cell differentiation; metal ion binding; negative regulation of granulocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; neurogenesis; palate development; positive regulation of transcription, DNA-dependent; regulation of cellular respiration; sequence-specific DNA binding; somatic stem cell maintenance; tongue development; transcription coactivator activity; transcription, DNA-dependent; transcriptional repressor complex; white fat cell differentiation",PF00096;PF13912;,,,,,,,,,PRD16_HUMAN,Homo sapiens (Human),"brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]" comp90052_c0_seq1,228,64.9123,0.88078617,0,19,,6.00E-11,Q6JQN1,Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-),GO:0003995; GO:0050660; GO:0016787; GO:0005739; GO:0016772,"acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; hydrolase activity; mitochondrion; transferase activity, transferring phosphorus-containing groups",PF00441;PF02770;PF02771;PF01636;PF13419;,,,,,,,,,ACD10_HUMAN,Homo sapiens (Human),fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088] comp90053_c0_seq1,449,42.7617,0.34818344,9,30,,3.00E-56,Q9D404,"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase)","3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase)",GO:0004315; GO:0006637; GO:0051792; GO:0005739; GO:0051790,3-oxoacyl-[acyl-carrier-protein] synthase activity; acyl-CoA metabolic process; medium-chain fatty acid biosynthetic process; mitochondrion; short-chain fatty acid biosynthetic process,PF00109;PF02801;,2.00E-33,CHOYP_OXSM.1.1,,,,,,,OXSM_MOUSE,Mus musculus (Mouse),acyl-CoA metabolic process [GO:0006637]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790] comp90071_c0_seq1,541,39.7412,0.19333043,14,12,,6.00E-29,Q9R1S3,GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N),GO:0006506; GO:0005789; GO:0016021; GO:0016780,"GPI anchor biosynthetic process; endoplasmic reticulum membrane; integral to membrane; phosphotransferase activity, for other substituted phosphate groups",PF01663;PF04987;,,,,,,,,,PIGN_MOUSE,Mus musculus (Mouse),GPI anchor biosynthetic process [GO:0006506] comp90087_c0_seq1,493,44.6247,0.32685603,8,21,,1.00E-41,O88496,Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase),Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase),GO:0009790; GO:0005789; GO:0008488; GO:0016021; GO:0043231; GO:0042277; GO:0017187; GO:0032571; GO:0019842,embryo development; endoplasmic reticulum membrane; gamma-glutamyl carboxylase activity; integral to membrane; intracellular membrane-bounded organelle; peptide binding; peptidyl-glutamic acid carboxylation; response to vitamin K; vitamin binding,PF05090;,2.00E-14,CHOYP_LOC101067681.1.1,,,,,,,VKGC_RAT,Rattus norvegicus (Rat),lung growth [GO:0060437]; peptidyl-glutamic acid carboxylation [GO:0017187]; response to dexamethasone [GO:0071548]; response to manganese ion [GO:0010042]; response to oxygen levels [GO:0070482]; response to parathyroid hormone [GO:0071107]; response to Thyroglobulin triiodothyronine [GO:1904016]; response to vitamin D [GO:0033280]; response to vitamin K [GO:0032571] comp90090_c0_seq1,264,44.3182,0.6217098,0,23,,8.00E-11,Q5DRD9,Protocadherin beta-10 (PCDH-beta-10),Protocadherin beta-10 (PCDH-beta-10),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;,,,,,,,,,PCDBA_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp90115_c0_seq1,377,41.6446,0.45184744,6,20,,2.00E-19,P49916,DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3),GO:0005524; GO:0003677; GO:0003910; GO:0051103; GO:0006284; GO:0051301; GO:0005694; GO:0006303; GO:0006273; GO:0043504; GO:0045910; GO:0005654; GO:0006289; GO:0007131; GO:0007283; GO:0000795; GO:0008270,ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligation involved in DNA repair; base-excision repair; cell division; chromosome; double-strand break repair via nonhomologous end joining; lagging strand elongation; mitochondrial DNA repair; negative regulation of DNA recombination; nucleoplasm; nucleotide-excision repair; reciprocal meiotic recombination; spermatogenesis; synaptonemal complex; zinc ion binding,PF04679;PF01068;PF04675;PF16759;PF00645;,4.00E-16,CHOYP_BRAFLDRAFT_119901.1.1,,,,,,,DNLI3_HUMAN,Homo sapiens (Human),"base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]" comp90121_c0_seq1,294,41.8367,0.47326751,15,2,,2.00E-33,Q8IV35,WD repeat-containing protein 49,WD repeat-containing protein 49,,,PF00400;,3.00E-48,CHOYP_LOC579391.1.1,,,,,,,WDR49_HUMAN,Homo sapiens (Human), comp90123_c0_seq1,650,42.7692,0.7418821,3,39,,4.00E-55,Q6VVW5,Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B),GO:0005524; GO:0005525; GO:0060348; GO:0097011; GO:0004383; GO:0016021; GO:0035556; GO:0016941; GO:0001503; GO:0017046; GO:0005886; GO:0004672; GO:0007168,ATP binding; GTP binding; bone development; cellular response to granulocyte macrophage colony-stimulating factor stimulus; guanylate cyclase activity; integral to membrane; intracellular signal transduction; natriuretic peptide receptor activity; ossification; peptide hormone binding; plasma membrane; protein kinase activity; receptor guanylyl cyclase signaling pathway,PF01094;PF00211;PF07714;,1.00E-45,CHOYP_ANPRB.2.2,,,,,,,ANPRB_MOUSE,Mus musculus (Mouse),bone development [GO:0060348]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]; single organism reproductive process [GO:0044702] comp90138_c0_seq1,595,40.8403,0.93315444,35,0,,4.00E-10,Q24155,Protein trunk,Protein trunk,GO:0005576; GO:0008358; GO:0007362; GO:0005122; GO:0008293,"extracellular region; maternal determination of anterior/posterior axis, embryo; terminal region determination; torso binding; torso signaling pathway",,,,,,,,,,TRUNK_DROME,Drosophila melanogaster (Fruit fly),"anterior/posterior axis specification, embryo [GO:0008595]; maternal determination of anterior/posterior axis, embryo [GO:0008358]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]" comp90144_c4_seq1,476,46.8487,0.28106185,9,19,,2.00E-38,Q8K4M9,Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1),Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1),GO:0005770; GO:0006869; GO:0005543,late endosome; lipid transport; phospholipid binding,PF12796;PF01237;,,,,,,,,,OSBL1_RAT,Rattus norvegicus (Rat),lipid transport [GO:0006869] comp90146_c0_seq1,392,48.4694,0.79092644,1,30,,,,,,,,,,,5.00E-19,ruditapes_c7954,,,,,,, comp90154_c0_seq1,583,45.6261,0.6936672,21,21,,1.00E-16,O14981,TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),GO:0005524; GO:0003677; GO:0004386; GO:0045892; GO:0005634; GO:0003700,"ATP binding; DNA binding; helicase activity; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity",PF12054;PF00271;PF00176;,5.00E-24,CHOYP_BTAF1.2.2,,,,,,,BTAF1_HUMAN,Homo sapiens (Human),"negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]" comp90179_c0_seq1,829,45.4765,0.47078911,35,10,,2.00E-143,P23098,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,0,CHOYP_DYHC.1.3,,,,,,,DYHC_TRIGR,Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp90180_c0_seq1,994,44.2656,0.86475975,2,0,,6.00E-111,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,4.00E-66,CHOYP_FASN.3.4,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp90180_c0_seq3,1063,44.9671,0.89466231,2,0,,1.00E-118,P12276,Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)],GO:0047451; GO:0004317; GO:0004316; GO:0004315; GO:0004313; GO:0004314; GO:0047117; GO:0004319; GO:0006633; GO:0016295; GO:0004320; GO:0016296; GO:0008270,"3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid biosynthetic process; myristoyl-[acyl-carrier-protein] hydrolase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding",PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;,,,,,,,,,FAS_CHICK,Gallus gallus (Chicken),fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] comp90185_c0_seq1,599,40.2337,0.74482966,19,27,,3.00E-46,Q9C0G0,Zinc finger protein 407,Zinc finger protein 407,GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",,8.00E-34,CHOYP_ZN407.1.1,,,,,,,ZN407_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp90188_c0_seq1,332,42.1687,0.68308312,11,5,,7.00E-40,Q2KIA0,Myocyte-specific enhancer factor 2C,Myocyte-specific enhancer factor 2C,GO:0001782; GO:0042100; GO:0050853; GO:0000165; GO:0001077; GO:0000983; GO:0003705; GO:0000977; GO:0006915; GO:0001568; GO:0001974; GO:0014898; GO:0003211; GO:0060536; GO:0071277; GO:0035690; GO:0071498; GO:0071222; GO:0071374; GO:0071560; GO:0035984; GO:0002062; GO:0003682; GO:0000987; GO:0001046; GO:0005737; GO:0048703; GO:0001958; GO:2001013; GO:0002467; GO:0072102; GO:0001947; GO:0006959; GO:0007611; GO:0030318; GO:0035198; GO:0030224; GO:0007521; GO:0050680; GO:0043524; GO:0030279; GO:0000122; GO:0072160; GO:0014033; GO:0048666; GO:0016607; GO:0001649; GO:0003151; GO:0060021; GO:0030220; GO:0030890; GO:0010694; GO:2000987; GO:0030501; GO:2000727; GO:0060045; GO:0071864; GO:2000111; GO:0045663; GO:0045666; GO:0045669; GO:0090073; GO:2001016; GO:0048643; GO:0003138; GO:0043234; GO:0002634; GO:0045652; GO:0060297; GO:0060025; GO:0003139; GO:0003185; GO:0035914; GO:0007519; GO:0051145; GO:0055012,B cell homeostasis; B cell proliferation; B cell receptor signaling pathway; MAPK cascade; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding; apoptotic process; blood vessel development; blood vessel remodeling; cardiac muscle hypertrophy in response to stress; cardiac ventricle formation; cartilage morphogenesis; cellular response to calcium ion; cellular response to drug; cellular response to fluid shear stress; cellular response to lipopolysaccharide; cellular response to parathyroid hormone stimulus; cellular response to transforming growth factor beta stimulus; cellular response to trichostatin A; chondrocyte differentiation; chromatin binding; core promoter proximal region sequence-specific DNA binding; core promoter sequence-specific DNA binding; cytoplasm; embryonic viscerocranium morphogenesis; endochondral ossification; epithelial cell proliferation involved in renal tubule morphogenesis; germinal center formation; glomerulus morphogenesis; heart looping; humoral immune response; learning or memory; melanocyte differentiation; miRNA binding; monocyte differentiation; muscle cell fate determination; negative regulation of epithelial cell proliferation; negative regulation of neuron apoptotic process; negative regulation of ossification; negative regulation of transcription from RNA polymerase II promoter; nephron tubule epithelial cell differentiation; neural crest cell differentiation; neuron development; nuclear speck; osteoblast differentiation; outflow tract morphogenesis; palate development; platelet formation; positive regulation of B cell proliferation; positive regulation of alkaline phosphatase activity; positive regulation of behavioral fear response; positive regulation of bone mineralization; positive regulation of cardiac muscle cell differentiation; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation in bone marrow; positive regulation of macrophage apoptotic process; positive regulation of myoblast differentiation; positive regulation of neuron differentiation; positive regulation of osteoblast differentiation; positive regulation of protein homodimerization activity; positive regulation of skeletal muscle cell differentiation; positive regulation of skeletal muscle tissue development; primary heart field specification; protein complex; regulation of germinal center formation; regulation of megakaryocyte differentiation; regulation of sarcomere organization; regulation of synaptic activity; secondary heart field specification; sinoatrial valve morphogenesis; skeletal muscle cell differentiation; skeletal muscle tissue development; smooth muscle cell differentiation; ventricular cardiac muscle cell differentiation,PF12347;PF00319;,9.00E-62,CHOYP_MEF2A.1.1,,,,,,,MEF2C_BOVIN,Bos taurus (Bovine),"apoptotic process [GO:0006915]; B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012]" comp90196_c0_seq1,697,43.472,0.46946559,8,22,,,,,,,,,3.00E-21,CHOYP_GEPH.2.2,,,,,,,,, comp90197_c0_seq1,317,38.4858,0.85553717,0,46,,3.00E-27,Q6DCW1,Zinc finger protein Gfi-1b (Growth factor independent protein 1B),Zinc finger protein Gfi-1b (Growth factor independent protein 1B),GO:0003677; GO:0016568; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; chromatin modification; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,5.00E-12,ruditapes_c18716,,,,,GFI1B_XENLA,Xenopus laevis (African clawed frog),"chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp90210_c0_seq1,404,62.3762,1.23980351,0,12,,2.00E-17,P0AGG2,Acyl-CoA thioesterase 2 (EC 3.1.2.-) (Acyl-CoA thioesterase II) (TEII),Acyl-CoA thioesterase 2 (EC 3.1.2.-) (Acyl-CoA thioesterase II) (TEII),GO:0047617; GO:0006637; GO:0009062,acyl-CoA hydrolase activity; acyl-CoA metabolic process; fatty acid catabolic process,,,,,,,,,,TESB_ECOLI,Escherichia coli (strain K12),acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062] comp90215_c1_seq1,485,37.9381,0.17234116,22,6,,5.00E-08,Q9QUN3,B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Lymphocyte antigen 57) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65),B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Lymphocyte antigen 57) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65),GO:0042113; GO:0005737; GO:0035556; GO:0005886,B cell activation; cytoplasm; intracellular signal transduction; plasma membrane,PF00017;,,,,,,,,,BLNK_MOUSE,Mus musculus (Mouse),B cell activation [GO:0042113]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556] comp90222_c0_seq1,298,43.9597,0.36163929,12,2,,5.00E-14,Q9Y3C0,WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53),WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53),GO:0071203,WASH complex,PF10152;,,,,,,,,,CCD53_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp90239_c0_seq1,237,50.6329,0.52904526,1,28,,,,,,,,,3.00E-34,CHOYP_BRAFLDRAFT_213839.1.2,,,,,,,,, comp90239_c1_seq1,355,42.8169,0.92468266,0,0,,,,,,,,,,,9.00E-35,ruditapes_c30619,,,,,,, comp90239_c1_seq2,617,48.9465,0.90591922,2,22,,1.00E-46,Q9Y289,Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6),Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6),GO:0006768; GO:0015878; GO:0031526; GO:0005887; GO:0015939; GO:0015887; GO:0008523; GO:0012506,biotin metabolic process; biotin transport; brush border membrane; integral to plasma membrane; pantothenate metabolic process; pantothenate transmembrane transport; sodium-dependent multivitamin transmembrane transporter activity; vesicle membrane,PF00474;,2.00E-11,CHOYP_BRAFLDRAFT_268046.1.3,8.00E-19,ruditapes_c23443,,,,,SC5A6_HUMAN,Homo sapiens (Human),biotin metabolic process [GO:0006768]; biotin transport [GO:0015878]; pantothenate metabolic process [GO:0015939]; pantothenate transmembrane transport [GO:0015887]; transmembrane transport [GO:0055085]; transport [GO:0006810] comp90246_c0_seq1,571,36.6025,0.38448361,464,254,,3.00E-75,Q9CQ46,EF-hand calcium-binding domain-containing protein 2,EF-hand calcium-binding domain-containing protein 2,GO:0005509,calcium ion binding,,1.00E-76,CHOYP_BRAFLDRAFT_122339.1.1,2.00E-128,ruditapes_c10366,,,,,EFCB2_MOUSE,Mus musculus (Mouse), comp90259_c0_seq2,424,38.4434,0.64102921,5,14,,,,,,,,,2.00E-26,CHOYP_LOC100569021.1.2,,,,,,,,, comp9025_c0_seq1,204,37.2549,0.99379119,3,0,,6.00E-06,Q9XSK2,CD63 antigen (CD antigen CD63),CD63 antigen (CD antigen CD63),GO:0016021; GO:0031902; GO:0005765; GO:0005886,integral to membrane; late endosome membrane; lysosomal membrane; plasma membrane,PF00335;,,,,,,,,,CD63_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] comp90261_c0_seq1,305,45.2459,0.32306091,9,13,,2.00E-25,O95905,Protein SGT1 (hSGT1) (Protein ecdysoneless homolog) (Suppressor of GCR2),Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1),GO:0008283; GO:0005737; GO:0005634; GO:2000045; GO:0006110; GO:0006355; GO:0003713; GO:0006366,"cell proliferation; cytoplasm; nucleus; regulation of G1/S transition of mitotic cell cycle; regulation of glycolysis; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription from RNA polymerase II promoter",PF07093;,9.00E-17,CHOYP_ECD.1.1,,,,,,,SGT1_HUMAN,Homo sapiens (Human),cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of glycolytic process [GO:0006110]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366] comp90268_c0_seq1,516,42.8295,0.72516774,8,25,,2.00E-22,Q8N859,Zinc finger protein 713,Zinc finger protein 713,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN713_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp90268_c2_seq1,242,47.9339,0.72777523,3,1,,4.00E-18,Q9BSG1,Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661),Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;,,,,,,,,,ZNF2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp90275_c0_seq1,540,46.6667,0.60304449,24,11,,2.00E-42,P35831,Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (MPTP-PEST) (Protein-tyrosine phosphatase P19) (P19-PTP),Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (MPTP-PEST) (Protein-tyrosine phosphatase P19) (P19-PTP),GO:0030054; GO:0042995; GO:0005829; GO:0035335; GO:0004721; GO:0002102; GO:0004725,cell junction; cell projection; cytosol; peptidyl-tyrosine dephosphorylation; phosphoprotein phosphatase activity; podosome; protein tyrosine phosphatase activity,PF00102;,2.00E-15,CHOYP_PHUM_PHUM574190.1.1,,,,,,,PTN12_MOUSE,Mus musculus (Mouse),cellular response to epidermal growth factor stimulus [GO:0071364]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; tissue regeneration [GO:0042246] comp90280_c0_seq1,746,48.5255,0.50177179,0,3,,2.00E-45,P91620,"Protein still life, isoforms C/SIF type 2","Protein still life, isoforms C/SIF type 2",GO:0030676; GO:0030054; GO:0035556; GO:0005543; GO:0051491; GO:0005057; GO:0032314; GO:0050770; GO:0050803; GO:0045202,Rac guanyl-nucleotide exchange factor activity; cell junction; intracellular signal transduction; phospholipid binding; positive regulation of filopodium assembly; receptor signaling protein activity; regulation of Rac GTPase activity; regulation of axonogenesis; regulation of synapse structure and activity; synapse,PF00169;PF02196;PF00621;,4.00E-26,CHOYP_AGAP_AGAP006590.1.1,,,,,,,SIF2_DROME,Drosophila melanogaster (Fruit fly),actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; positive regulation of filopodium assembly [GO:0051491]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synapse structure or activity [GO:0050803] comp90280_c0_seq2,773,47.9948,0.49494328,2,0,,3.00E-10,Q96N96,Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2),Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2),GO:0030676; GO:0016477; GO:0005737; GO:0030175; GO:0046847; GO:0030027; GO:0030032; GO:0005634; GO:0005543; GO:0035023; GO:0030334; GO:0032587,Rac guanyl-nucleotide exchange factor activity; cell migration; cytoplasm; filopodium; filopodium assembly; lamellipodium; lamellipodium assembly; nucleus; phospholipid binding; regulation of Rho protein signal transduction; regulation of cell migration; ruffle membrane,PF00169;PF00621;PF00018;,,,,,,,,,SPT13_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; regulation of cell migration [GO:0030334]; regulation of Rho protein signal transduction [GO:0035023] comp90287_c0_seq1,634,32.1767,0.61034369,42,6,,2.00E-07,P08548,LINE-1 reverse transcriptase homolog (EC 2.7.7.49),LINE-1 reverse transcriptase homolog (EC 2.7.7.49),GO:0003723; GO:0006278; GO:0003964; GO:0046872,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; metal ion binding,PF08333;PF03372;PF00078;,,,,,,,,,LIN1_NYCCO,Nycticebus coucang (Slow loris), comp90304_c0_seq1,283,44.523,0.72009013,12,5,,6.00E-10,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp90305_c0_seq1,1623,31.7314,0.66065521,89347,2317,,1.00E-64,B0FWD8,NADH-ubiquinone oxidoreductase chain 1 (EC 1.6.5.3) (NADH dehydrogenase subunit 1),NADH-ubiquinone oxidoreductase chain 1 (EC 1.6.5.3) (NADH dehydrogenase subunit 1),GO:0008137; GO:0016021; GO:0005743; GO:0070469,NADH dehydrogenase (ubiquinone) activity; integral to membrane; mitochondrial inner membrane; respiratory chain,PF00146;,,,5.00E-27,ruditapes_c60,,,,,NU1M_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp90308_c0_seq1,350,46,0.87422881,8,12,,4.00E-25,Q28WQ1,Kinesin-like protein unc-104,Kinesin-like protein unc-104,GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0005875; GO:0003777; GO:0005543; GO:0048489; GO:0047496,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule associated complex; microtubule motor activity; phospholipid binding; synaptic vesicle transport; vesicle transport along microtubule,PF12473;PF12423;PF00225;PF16183;PF00169;,,,,,,,,,KIF1A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] comp90308_c1_seq1,476,42.0168,0.62916268,13,23,,,,,,,,,2.00E-22,CHOYP_LOC100875479.2.2,,,,,,,,, comp90312_c0_seq1,683,46.5593,0.24967607,18,2,,,,,,,,,2.00E-16,CHOYP_LOC581313.2.2,,,,,,,,, comp90331_c0_seq1,430,46.0465,0.35212609,23,4,,9.00E-37,Q6R327,Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3),Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3),GO:0038095; GO:0031295; GO:0031929; GO:0031932; GO:0031532; GO:0005829; GO:0009790; GO:0007173; GO:0008543; GO:0045087; GO:0048011; GO:0048015; GO:0032008; GO:0030838; GO:0050731; GO:0032314; GO:0032956; GO:0030334; GO:0051896; GO:0043022,Fc-epsilon receptor signaling pathway; T cell costimulation; TOR signaling cascade; TORC2 complex; actin cytoskeleton reorganization; cytosol; embryo development; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; neurotrophin TRK receptor signaling pathway; phosphatidylinositol-mediated signaling; positive regulation of TOR signaling cascade; positive regulation of actin filament polymerization; positive regulation of peptidyl-tyrosine phosphorylation; regulation of Rac GTPase activity; regulation of actin cytoskeleton organization; regulation of cell migration; regulation of protein kinase B signaling cascade; ribosome binding,PF14663;PF14666;PF14664;PF14665;PF14668;,1.00E-23,CHOYP_LOC100367446.1.1,,,,,,,RICTR_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment of cell polarity [GO:0030010]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of phosphorylation [GO:0042325]; regulation of protein kinase B signaling [GO:0051896]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929] comp90334_c0_seq1,2036,43.9587,0.39881034,51420,152607,,0,Q5R546,"ATP synthase subunit alpha, mitochondrial","ATP synthase subunit alpha, mitochondrial",GO:0005524; GO:0015991; GO:0015986; GO:0005753; GO:0005886; GO:0046933; GO:0045261; GO:0046961,"ATP binding; ATP hydrolysis coupled proton transport; ATP synthesis coupled proton transport; mitochondrial proton-transporting ATP synthase complex; plasma membrane; proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATP synthase complex, catalytic core F(1); proton-transporting ATPase activity, rotational mechanism",PF00006;PF00306;PF02874;,0,CHOYP_ATPA.1.1,0,ruditapes2_c343,,,,,ATPA_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986] comp90340_c0_seq1,878,29.6128,0.73767492,48243,584,,1.00E-13,Q34946,ATP synthase subunit a (F-ATPase protein 6),ATP synthase subunit a (F-ATPase protein 6),GO:0015986; GO:0015078; GO:0016021; GO:0005743; GO:0045263,"ATP synthesis coupled proton transport; hydrogen ion transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; proton-transporting ATP synthase complex, coupling factor F(o)",PF00119;,,,,,,,,,ATP6_LUMTE,Lumbricus terrestris (Common earthworm),ATP synthesis coupled proton transport [GO:0015986] comp90340_c1_seq1,506,39.1304,0.87489557,69366,1674,,,,,,,,,2.00E-35,CHOYP_MTRNR2L8.1.1,5.00E-40,ruditapes_c16723,,,,,,, comp90340_c2_seq1,669,24.2152,1.00752105,21196,367,,,,,,,,,,,1.00E-23,ruditapes2_c3039,,,,,,, comp90343_c0_seq1,209,49.7608,0.80647008,4,0,,2.00E-20,P23659,"Endoglucanase Z (EC 3.2.1.4) (Avicelase I) (Endo-1,4-beta-glucanase) (Thermoactive cellulase)","Endoglucanase Z (EC 3.2.1.4) (Avicelase I) (Endo-1,4-beta-glucanase) (Thermoactive cellulase)",GO:0008810; GO:0030248; GO:0030245,cellulase activity; cellulose binding; cellulose catabolic process,PF00942;PF03442;PF00759;,1.00E-20,CHOYP_NEMVEDRAFT_V1G83869.1.3,,,,,,,GUNZ_CLOSR,Clostridium stercorarium,cellulose catabolic process [GO:0030245] comp90384_c0_seq1,2131,41.5767,0.77923994,21280,104061,,3.00E-14,Q8NC51,Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1),Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1),GO:0005737; GO:0003730; GO:0005634; GO:0048471; GO:0005886; GO:0043488,cytoplasm; mRNA 3'-UTR binding; nucleus; perinuclear region of cytoplasm; plasma membrane; regulation of mRNA stability,PF04774;PF16174;,4.00E-13,CHOYP_BRAFLDRAFT_60200.1.3,3.00E-24,ruditapes2_c304,,,,,PAIRB_HUMAN,Homo sapiens (Human),regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488] comp90415_c0_seq1,225,61.3333,0.95260048,0,14,,3.00E-46,Q6A9X0,Lipoyl synthase (EC 2.8.1.8) (Lip-syn) (LS) (Lipoate synthase) (Lipoic acid synthase) (Sulfur insertion protein LipA),Lipoyl synthase (EC 2.8.1.8) (Lip-syn) (LS) (Lipoate synthase) (Lipoic acid synthase) (Sulfur insertion protein LipA),GO:0051539; GO:0005737; GO:0016992; GO:0046872; GO:0009249,"4 iron, 4 sulfur cluster binding; cytoplasm; lipoate synthase activity; metal ion binding; protein lipoylation",PF16881;PF04055;,,,,,,,,,LIPA_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),protein lipoylation [GO:0009249] comp90418_c1_seq1,293,48.4642,0.46695005,8,12,,1.00E-18,O15013,Rho guanine nucleotide exchange factor 10,Rho guanine nucleotide exchange factor 10,GO:0005089; GO:0005813; GO:0051298; GO:0005829; GO:0022011; GO:0033126; GO:0051496; GO:0035023; GO:0090307,Rho guanyl-nucleotide exchange factor activity; centrosome; centrosome duplication; cytosol; myelination in peripheral nervous system; positive regulation of GTP catabolic process; positive regulation of stress fiber assembly; regulation of Rho protein signal transduction; spindle assembly involved in mitosis,PF00621;,2.00E-13,CHOYP_PHUM_PHUM169900.2.2,,,,,,,ARHGA_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496]; regulation of Rho protein signal transduction [GO:0035023] comp90420_c0_seq1,284,43.3099,0.90573157,1,18,,2.00E-17,Q17RR3,Pancreatic lipase-related protein 3 (PL-RP3) (EC 3.1.1.3),Pancreatic lipase-related protein 3 (PL-RP3) (EC 3.1.1.3),GO:0005576; GO:0016042; GO:0004806,extracellular region; lipid catabolic process; triglyceride lipase activity,PF00151;PF01477;,,,,,,,,,LIPR3_HUMAN,Homo sapiens (Human),lipid catabolic process [GO:0016042] comp90421_c0_seq1,1302,42.4731,0.41629418,60597,219062,,2.00E-148,Q4PMB3,40S ribosomal protein S4,40S ribosomal protein S4,GO:0019843; GO:0005840; GO:0003735; GO:0006412,rRNA binding; ribosome; structural constituent of ribosome; translation,PF16121;PF00467;PF00900;PF08071;PF01479;,4.00E-136,CHOYP_RS4.2.11,0,ruditapes2_c3108,,,,,RS4_IXOSC,Ixodes scapularis (Black-legged tick) (Deer tick),translation [GO:0006412] comp90424_c0_seq1,2421,41.5944,0.53922373,43038,413437,,0,P63018,Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8),Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8),GO:0043531; GO:0005524; GO:0042623; GO:0000974; GO:0008380; GO:0051085; GO:0070062; GO:0006397; GO:0042470; GO:0045892; GO:0043005; GO:0043025; GO:0005730; GO:0006950; GO:0030529; GO:0005681; GO:0008021; GO:0006351; GO:0051082,"ADP binding; ATP binding; ATPase activity, coupled; Prp19 complex; RNA splicing; chaperone mediated protein folding requiring cofactor; extracellular vesicular exosome; mRNA processing; melanosome; negative regulation of transcription, DNA-dependent; neuron projection; neuronal cell body; nucleolus; response to stress; ribonucleoprotein complex; spliceosomal complex; synaptic vesicle; transcription, DNA-dependent; unfolded protein binding",PF00012;,0,CHOYP_HSP7D.2.3,4.00E-100,ruditapes2_c147,,,,,HSP7C_RAT,Rattus norvegicus (Rat),"aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]" comp90429_c0_seq1,763,44.8231,0.28741499,55800,162926,,1.00E-100,Q4R5P3,60S ribosomal protein L10a,60S ribosomal protein L10a,GO:0003723; GO:0015934; GO:0003735; GO:0006412,RNA binding; large ribosomal subunit; structural constituent of ribosome; translation,PF00687;,2.00E-100,CHOYP_RL10A.1.2,2.00E-168,ruditapes_lrc16646,,,,,RL10A_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),translation [GO:0006412] comp90430_c0_seq1,430,44.6512,0.75226762,46524,84358,,1.00E-33,Q9VXX8,Probable 60S ribosomal protein L37-A,Probable 60S ribosomal protein L37-A,GO:0046872; GO:0019843; GO:0005840; GO:0003735; GO:0006412,metal ion binding; rRNA binding; ribosome; structural constituent of ribosome; translation,PF01907;,3.00E-38,CHOYP_LOC100533258.1.6,2.00E-82,ruditapes_c1897,,,,,RL371_DROME,Drosophila melanogaster (Fruit fly),translation [GO:0006412] comp90431_c1_seq1,555,35.8559,0.22885442,42366,40851,,2.00E-24,Q95V84,60S ribosomal protein L38,60S ribosomal protein L38,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01781;,9.00E-52,CHOYP_NEMVEDRAFT_V1G226298.1.7,2.00E-63,ruditapes2_c5457,,,,,RL38_BRABE,Branchiostoma belcheri (Amphioxus),translation [GO:0006412] comp90436_c0_seq1,743,41.7227,0.46500084,85596,157250,,2.00E-75,Q9VNE9,60S ribosomal protein L13a,60S ribosomal protein L13a,GO:0007219; GO:0051298; GO:0008407; GO:0015934; GO:0005840; GO:0003735; GO:0006412,Notch signaling pathway; centrosome duplication; chaeta morphogenesis; large ribosomal subunit; ribosome; structural constituent of ribosome; translation,PF00572;,3.00E-91,CHOYP_ISCW_ISCW019130.1.2,1.00E-131,ruditapes_lrc32357,,,,,RL13A_DROME,Drosophila melanogaster (Fruit fly),centrosome duplication [GO:0051298]; chaeta morphogenesis [GO:0008407]; Notch signaling pathway [GO:0007219]; translation [GO:0006412] comp90437_c0_seq1,516,44.3798,0.44415974,45922,112538,,9.00E-71,P84175,40S ribosomal protein S12,40S ribosomal protein S12,GO:0022627; GO:0003735; GO:0006412,cytosolic small ribosomal subunit; structural constituent of ribosome; translation,PF01248;,1.00E-113,CHOYP_Y059.1.1,1.00E-117,ruditapes2_c4069,,,,,RS12_CHICK,Gallus gallus (Chicken),translation [GO:0006412] comp90438_c0_seq1,544,40.2574,0.59748895,26,33,,8.00E-22,Q5T0B9,Zinc finger protein 362,Zinc finger protein 362,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN362_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp90450_c0_seq2,844,43.9573,0.54056488,0,0,,5.00E-38,Q12979,Active breakpoint cluster region-related protein,Active breakpoint cluster region-related protein,GO:0005096; GO:0030675; GO:0005089; GO:0030036; GO:0097190; GO:0007420; GO:0005829; GO:0042472; GO:0030336; GO:0050728; GO:0043314; GO:0050885; GO:0048011; GO:0005543; GO:0005886; GO:0043065; GO:0050766; GO:0051056; GO:0032496; GO:0007264,GTPase activator activity; Rac GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; actin cytoskeleton organization; apoptotic signaling pathway; brain development; cytosol; inner ear morphogenesis; negative regulation of cell migration; negative regulation of inflammatory response; negative regulation of neutrophil degranulation; neuromuscular process controlling balance; neurotrophin TRK receptor signaling pathway; phospholipid binding; plasma membrane; positive regulation of apoptotic process; positive regulation of phagocytosis; regulation of small GTPase mediated signal transduction; response to lipopolysaccharide; small GTPase mediated signal transduction,PF00168;PF00169;PF00620;PF00621;,,,,,,,,,ABR_HUMAN,Homo sapiens (Human),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phagocytosis [GO:0050766]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]; small GTPase mediated signal transduction [GO:0007264] comp90451_c0_seq1,1020,39.902,0.64167333,142851,342754,,5.00E-109,O01802,60S ribosomal protein L7,60S ribosomal protein L7,GO:0003723; GO:0005840,RNA binding; ribosome,PF00327;PF08079;,5.00E-115,CHOYP_RL7.1.2,8.00E-180,ruditapes2_lrc3447,,,,,RL7_CAEEL,Caenorhabditis elegans,"cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]" comp90456_c0_seq1,325,45.8462,0.65271823,12,4,,7.00E-43,Q92831,Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF),Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF),GO:0031672; GO:0005671; GO:0031674; GO:0018076; GO:0007219; GO:0000125; GO:0042641; GO:0007050; GO:0032869; GO:0006338; GO:0004861; GO:0043966; GO:0004402; GO:0000776; GO:0004468; GO:0019048; GO:0008285; GO:0045736; GO:0045944; GO:0032403; GO:0019901; GO:0010835; GO:0003713; GO:0006361; GO:0006367,A band; Ada2/Gcn5/Ada3 transcription activator complex; I band; N-terminal peptidyl-lysine acetylation; Notch signaling pathway; PCAF complex; actomyosin; cell cycle arrest; cellular response to insulin stimulus; chromatin remodeling; cyclin-dependent protein serine/threonine kinase inhibitor activity; histone H3 acetylation; histone acetyltransferase activity; kinetochore; lysine N-acetyltransferase activity; modulation by virus of host morphology or physiology; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; positive regulation of transcription from RNA polymerase II promoter; protein complex binding; protein kinase binding; regulation of protein ADP-ribosylation; transcription coactivator activity; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter,PF00583;PF00439;PF06466;,1.00E-22,CHOYP_KAT2B.1.1,,,,,,,KAT2B_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to parathyroid hormone stimulus [GO:0071374]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; memory [GO:0007613]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of chromatin binding [GO:0035563]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vasodilation [GO:0045909]; protein acetylation [GO:0006473]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]" comp90466_c0_seq1,475,42.1053,0.3332348,12,0,,4.00E-34,Q5XPI4,E3 ubiquitin-protein ligase RNF123 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123),E3 ubiquitin-protein ligase RNF123 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123),GO:0005737; GO:0016874; GO:0016567; GO:0008270,cytoplasm; ligase activity; protein ubiquitination; zinc ion binding,PF00622;,,,,,,,,,RN123_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp90469_c0_seq1,761,43.1012,0.66469565,55656,216866,,2.00E-111,Q8WQI5,40S ribosomal protein S8,40S ribosomal protein S8,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01201;,8.00E-67,CHOYP_NPL4.1.1,3.00E-164,ruditapes_lrc33842,,,,,RS8_SPOFR,Spodoptera frugiperda (Fall armyworm),translation [GO:0006412] comp90471_c0_seq1,524,44.2748,0.60919229,48093,143269,,7.00E-23,O61463,60S acidic ribosomal protein P2,60S acidic ribosomal protein P2,GO:0005840; GO:0003735; GO:0006414,ribosome; structural constituent of ribosome; translational elongation,,6.00E-22,CHOYP_RLA2.4.9,2.00E-57,ruditapes_lrc26499,,,,,RLA2_CRYST,Cryptochiton stelleri (Giant gumboot chiton),translational elongation [GO:0006414] comp90475_c0_seq1,719,40.612,0.47290732,104239,149393,,1.00E-93,P62083,40S ribosomal protein S7 (S8),40S ribosomal protein S7 (S8),GO:0030686; GO:0022627; GO:0005815; GO:0006364; GO:0042274; GO:0032040; GO:0003735; GO:0006412,90S preribosome; cytosolic small ribosomal subunit; microtubule organizing center; rRNA processing; ribosomal small subunit biogenesis; small-subunit processome; structural constituent of ribosome; translation,PF01251;,5.00E-139,CHOYP_RS7.6.9,0,ruditapes_lrc12146,,,,,RS7_RAT,Rattus norvegicus (Rat),ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] comp9050_c0_seq1,284,47.5352,2.10654786,10,0,,,,,,,,,5.00E-45,CHOYP_contig_008404,,,,,,,,, comp90510_c0_seq1,1327,41.5976,0.61606196,29618,62437,,4.00E-56,Q96AJ9,Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2),Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2),GO:0005794; GO:0000139; GO:0005484; GO:0031201; GO:0016023; GO:0016021; GO:0006886; GO:0042147,"Golgi apparatus; Golgi membrane; SNAP receptor activity; SNARE complex; cytoplasmic membrane-bounded vesicle; integral to membrane; intracellular protein transport; retrograde transport, endosome to Golgi",PF05008;,1.00E-66,CHOYP_NEMVEDRAFT_V1G237122.6.6,2.00E-95,ruditapes2_c4998,,,,,VTI1A_HUMAN,Homo sapiens (Human),"autophagy [GO:0006914]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi ribbon formation [GO:0090161]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion with Golgi apparatus [GO:0048280]; voluntary musculoskeletal movement [GO:0050882]" comp90512_c0_seq1,933,39.2283,1.04998146,51,9,,2.00E-20,Q9Y5H1,Protocadherin gamma-A2 (PCDH-gamma-A2),Protocadherin gamma-A2 (PCDH-gamma-A2),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;PF15974;,,,,,,,,,PCDG2_HUMAN,Homo sapiens (Human),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp90541_c0_seq1,564,49.1135,0.47201485,23,0,,2.00E-29,Q0WYX8,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,MAM domain-containing glycosylphosphatidylinositol anchor protein 1,GO:0046658; GO:0001764,anchored to plasma membrane; neuron migration,PF00629;,9.00E-14,CHOYP_NEMVEDRAFT_V1G239043.2.6,2.00E-14,ruditapes_c12717,,,,,MDGA1_CHICK,Gallus gallus (Chicken),neuron migration [GO:0001764] comp90556_c0_seq2,520,35,0.69215232,504,1542,,6.00E-11,P05632,"ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon)","ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon)",GO:0015986; GO:0005753; GO:0000275; GO:0046933; GO:0046961,"ATP synthesis coupled proton transport; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1); proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATPase activity, rotational mechanism",PF04627;,,,,,,,,,ATP5E_BOVIN,Bos taurus (Bovine),ATP synthesis coupled proton transport [GO:0015986] comp9055_c0_seq1,229,69.4323,0.83969855,0,8,,7.00E-12,A3DHH6,GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I),GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I),GO:0035998; GO:0005525; GO:0003934; GO:0005737; GO:0006730; GO:0046654; GO:0008270,"7,8-dihydroneopterin 3'-triphosphate biosynthetic process; GTP binding; GTP cyclohydrolase I activity; cytoplasm; one-carbon metabolic process; tetrahydrofolate biosynthetic process; zinc ion binding",PF01227;,,,,,,,,,GCH1_CLOTH,Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum),"7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]" comp90565_c0_seq1,1141,37.3357,0.55553387,9,38,,8.00E-91,A2AIL4,"NADH dehydrogenase (ubiquinone) complex I, assembly factor 6","NADH dehydrogenase (ubiquinone) complex I, assembly factor 6",GO:0009058; GO:0005743; GO:0032981; GO:0005739; GO:0016740,biosynthetic process; mitochondrial inner membrane; mitochondrial respiratory chain complex I assembly; mitochondrion; transferase activity,PF00494;,,,,,,,,,NDUF6_MOUSE,Mus musculus (Mouse),biosynthetic process [GO:0009058]; mitochondrial respiratory chain complex I assembly [GO:0032981] comp90565_c0_seq3,1084,37.6384,0.52269049,4,0,,1.00E-08,P17056,Phytoene synthase (PSase) (EC 2.5.1.-),Phytoene synthase (PSase) (EC 2.5.1.-),GO:0016117; GO:0016767; GO:0046872,carotenoid biosynthetic process; geranylgeranyl-diphosphate geranylgeranyltransferase activity; metal ion binding,PF00494;,,,,,,,,,CRTB_RHOCB,Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003),carotenoid biosynthetic process [GO:0016117] comp90575_c0_seq1,294,47.9592,0.29858645,10,0,,5.00E-15,Q86TV6,Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1),,,PF13181;,,,,,,,,,TTC7B_HUMAN,Homo sapiens (Human),establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854] comp90583_c0_seq1,313,47.2843,0.175225,13,22,,6.00E-25,O09012,Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (PXR1P) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1),Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (PXR1P) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1),GO:0048468; GO:0021795; GO:0021895; GO:0005829; GO:0007029; GO:0006635; GO:0007006; GO:0050905; GO:0001764; GO:0005778; GO:0005052; GO:0040018; GO:0008022; GO:0016560; GO:0006625; GO:0000038,"cell development; cerebral cortex cell migration; cerebral cortex neuron differentiation; cytosol; endoplasmic reticulum organization; fatty acid beta-oxidation; mitochondrial membrane organization; neuromuscular process; neuron migration; peroxisomal membrane; peroxisome matrix targeting signal-1 binding; positive regulation of multicellular organism growth; protein C-terminus binding; protein import into peroxisome matrix, docking; protein targeting to peroxisome; very long-chain fatty acid metabolic process",PF13374;,2.00E-19,CHOYP_PEX5.2.2,,,,,,,PEX5_MOUSE,Mus musculus (Mouse),"cell development [GO:0048468]; cellular lipid metabolic process [GO:0044255]; cerebral cortex cell migration [GO:0021795]; cerebral cortex neuron differentiation [GO:0021895]; endoplasmic reticulum organization [GO:0007029]; fatty acid beta-oxidation [GO:0006635]; mitochondrial membrane organization [GO:0007006]; mitochondrion organization [GO:0007005]; negative regulation of protein homotetramerization [GO:1901094]; neuromuscular process [GO:0050905]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; positive regulation of multicellular organism growth [GO:0040018]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein import into peroxisome matrix, translocation [GO:0016561]; protein import into peroxisome membrane [GO:0045046]; protein targeting to peroxisome [GO:0006625]; protein tetramerization [GO:0051262]; very long-chain fatty acid metabolic process [GO:0000038]" comp90590_c0_seq1,276,33.6957,0.65331046,10,13,,5.00E-06,Q5R8Z6,Multiple coagulation factor deficiency protein 2 homolog,Multiple coagulation factor deficiency protein 2 homolog,GO:0005794; GO:0005509; GO:0005783; GO:0005793; GO:0015031; GO:0016192,Golgi apparatus; calcium ion binding; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; protein transport; vesicle-mediated transport,PF13499;,8.00E-11,CHOYP_DPSE_GA30097.1.1,,,,,,,MCFD2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp90606_c1_seq1,209,57.8947,0.9180538,0,4,,2.00E-08,O34518,Putative ABC transporter permease protein AmyC,Putative ABC transporter permease protein AmyC,GO:0016021; GO:0005886; GO:0005215,integral to membrane; plasma membrane; transporter activity,PF00528;,,,,,,,,,AMYC_BACSU,Bacillus subtilis (strain 168),transport [GO:0006810] comp90611_c0_seq1,473,41.8605,0.48486305,6,12,,6.00E-36,Q9Y2L5,Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),Trafficking protein particle complex subunit 8 (Protein TRS85 homolog),GO:0006888; GO:0005794; GO:0005801,ER to Golgi vesicle-mediated transport; Golgi apparatus; cis-Golgi network,PF12739;,,,,,,,,,TPPC8_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497] comp90620_c0_seq1,539,42.4861,0.49930824,9,41,,2.00E-08,P30432,Furin-like protease 2 (Furin-2) (EC 3.4.21.75),Furin-like protease 2 (Furin-2) (EC 3.4.21.75),GO:0016021; GO:0005886; GO:0006508; GO:0004252,integral to membrane; plasma membrane; proteolysis; serine-type endopeptidase activity,PF14843;PF01483;PF00082;PF16470;,,,,,,,,,FUR2_DROME,Drosophila melanogaster (Fruit fly),negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906] comp90622_c0_seq1,399,36.3409,0.38358507,7,12,,3.00E-48,Q7T385,V-type proton ATPase subunit C 1-A (V-ATPase subunit C 1-A) (Vacuolar proton pump subunit C 1-A),V-type proton ATPase subunit C 1-A (V-ATPase subunit C 1-A) (Vacuolar proton pump subunit C 1-A),GO:0015991; GO:0015078; GO:0033180,"ATP hydrolysis coupled proton transport; hydrogen ion transmembrane transporter activity; proton-transporting V-type ATPase, V1 domain",PF03223;,3.00E-11,CHOYP_VATC1.1.1,,,,,,,VTC1A_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),ATP hydrolysis coupled proton transport [GO:0015991] comp90626_c0_seq1,630,35.2381,0.41377153,8398,11788,,1.00E-32,Q02366,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit),GO:0005747; GO:0055114; GO:0006979,mitochondrial respiratory chain complex I; oxidation-reduction process; response to oxidative stress,PF05347;,,,4.00E-35,ruditapes2_c1438,,,,,NDUA6_BOVIN,Bos taurus (Bovine),oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979] comp90643_c0_seq1,564,36.8794,0.78618058,2206,16618,,3.00E-28,Q76LT9,Transmembrane protein 258 (Protein NEF1),Transmembrane protein 258 (Protein NEF1),GO:0016021,integral to membrane,PF05251;,2.00E-41,CHOYP_TM258.3.3,3.00E-69,ruditapes2_c158,,,,,NEF1_CHICK,Gallus gallus (Chicken), comp90652_c1_seq1,298,43.9597,1.00144668,0,40,,2.00E-20,Q5T1H1,Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog),Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog),GO:0005509; GO:0005576; GO:0050896; GO:0007601,calcium ion binding; extracellular region; response to stimulus; visual perception,PF00008;PF12661;PF00054;PF02210;,,,,,,,,,EYS_HUMAN,Homo sapiens (Human),detection of light stimulus involved in visual perception [GO:0050908]; skeletal muscle tissue regeneration [GO:0043403] comp90652_c2_seq1,218,44.9541,0.7551883,0,1,,5.00E-11,Q5R6R1,Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) (Fragment),Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) (Fragment),GO:0005576; GO:0050896; GO:0007601,extracellular region; response to stimulus; visual perception,PF00008;PF00054;,,,,,,,,,EYS_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),response to stimulus [GO:0050896]; visual perception [GO:0007601] comp90654_c0_seq1,1090,41.0092,0.50254388,40,4,,4.00E-122,Q8IY22,C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip),C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip),GO:0005737; GO:0005634; GO:0005543,cytoplasm; nucleus; phospholipid binding,,6.00E-165,CHOYP_LOC101168708.1.1,,,,,,,CMIP_HUMAN,Homo sapiens (Human), comp90657_c0_seq1,934,45.3961,0.41615715,31,26,,1.00E-24,A2A9C3,Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_MOUSE,Mus musculus (Mouse),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp90667_c0_seq2,582,47.5945,0.33913374,6,1,,4.00E-21,Q6GPJ8,Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2),Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2),GO:0030030; GO:0005737; GO:0005815,cell projection organization; cytoplasm; microtubule organizing center,,,,,,,,,,CEP97_XENLA,Xenopus laevis (African clawed frog),cell projection organization [GO:0030030] comp90682_c0_seq1,723,43.9834,0.40107706,41,8,,2.00E-22,Q8R420,ATP-binding cassette sub-family A member 3,ATP-binding cassette sub-family A member 3,GO:0005524; GO:0006200; GO:0016887; GO:0097233; GO:0016021; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; alveolar lamellar body membrane; integral to membrane; plasma membrane; transport,PF00005;,,,,,,,,,ABCA3_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810] comp90695_c1_seq1,228,47.3684,1.02093871,4,8,,,,,,,,,8.00E-16,CHOYP_LOC585963.1.2,,,,,,,,, comp90699_c1_seq1,226,49.5575,0.38254878,0,9,,8.00E-12,Q99884,Sodium-dependent proline transporter (Solute carrier family 6 member 7),Sodium-dependent proline transporter (Solute carrier family 6 member 7),GO:0005887; GO:0005328; GO:0015824; GO:0055085,integral to plasma membrane; neurotransmitter:sodium symporter activity; proline transport; transmembrane transport,PF00209;,,,,,,,,,SC6A7_HUMAN,Homo sapiens (Human),proline transport [GO:0015824]; transport [GO:0006810] comp90702_c0_seq1,362,48.3425,0.96800739,7,15,,3.00E-09,Q2VLG6,Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)],GO:0006953; GO:0005576; GO:0016021; GO:0005886; GO:0005044,acute-phase response; extracellular region; integral to membrane; plasma membrane; scavenger receptor activity,PF00530;,,,,,,,,,C163A_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),acute-phase response [GO:0006953] comp90708_c1_seq1,219,36.9863,0.55556714,24,119,,,,,,,,,,,3.00E-12,ruditapes_c27792,,,,,,, comp90710_c0_seq1,463,49.0281,0.28860343,17,0,,8.00E-19,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,2.00E-71,CHOYP_LOC584771.1.1,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp90715_c0_seq1,354,60.1695,0.97200917,0,27,,8.00E-23,O34245,Anaerobic C4-dicarboxylate transporter DcuA,Anaerobic C4-dicarboxylate transporter DcuA,GO:0015556; GO:0016021; GO:0005886,C4-dicarboxylate transmembrane transporter activity; integral to membrane; plasma membrane,PF03605;,,,,,,,,,DCUA_WOLSU,Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes), comp90724_c0_seq1,240,54.1667,1.12204839,0,8,,9.00E-33,Q8NR12,Ribose import ATP-binding protein RbsA (EC 3.6.3.17),Ribose import ATP-binding protein RbsA (EC 3.6.3.17),GO:0005524; GO:0006200; GO:0015407; GO:0005886,ATP binding; ATP catabolic process; monosaccharide-transporting ATPase activity; plasma membrane,PF00005;,,,,,,,,,RBSA_CORGL,Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025), comp90726_c0_seq1,693,42.8571,0.38652267,14,24,,6.00E-92,Q8R059,UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase),UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-galactose 4-epimerase),GO:0003978; GO:0044237; GO:0050662; GO:0019388; GO:0006012,UDP-glucose 4-epimerase activity; cellular metabolic process; coenzyme binding; galactose catabolic process; galactose metabolic process,PF16363;,5.00E-82,CHOYP_LOC100370520.1.1,4.00E-24,ruditapes_c23539,,,,,GALE_MOUSE,Mus musculus (Mouse),galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] comp90737_c0_seq1,399,38.3459,0.54738626,9,14,,9.00E-21,Q92562,"Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)","Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)",GO:0000139; GO:0008219; GO:0031901; GO:0031902; GO:0007626; GO:0032288; GO:0031642; GO:0048666; GO:0043813; GO:0004438; GO:0043812; GO:0043473; GO:0010976; GO:0044281; GO:0007033,"Golgi membrane; cell death; early endosome membrane; late endosome membrane; locomotory behavior; myelin assembly; negative regulation of myelination; neuron development; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; pigmentation; positive regulation of neuron projection development; small molecule metabolic process; vacuole organization",PF02383;,,,,,,,,,FIG4_HUMAN,Homo sapiens (Human),locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] comp90791_c0_seq1,224,45.5357,0.52632628,6,2,,1.00E-17,P51569,Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase),GO:0005794; GO:0004557; GO:0005576; GO:0016139; GO:0046477; GO:0005764; GO:0045019; GO:0051001; GO:0009311; GO:0042803; GO:0052692; GO:0005102,Golgi apparatus; alpha-galactosidase activity; extracellular region; glycoside catabolic process; glycosylceramide catabolic process; lysosome; negative regulation of nitric oxide biosynthetic process; negative regulation of nitric-oxide synthase activity; oligosaccharide metabolic process; protein homodimerization activity; raffinose alpha-galactosidase activity; receptor binding,PF16499;,,,,,,,,,AGAL_MOUSE,Mus musculus (Mouse),glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311] comp90812_c0_seq1,567,44.7972,0.53571595,14,21,,2.00E-22,Q04786,Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase),Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase),GO:0004563; GO:0006032; GO:0030247; GO:0000272,beta-N-acetylhexosaminidase activity; chitin catabolic process; polysaccharide binding; polysaccharide catabolic process,PF03173;PF00728;PF02838;,,,,,,,,,HEX_VIBVL,Vibrio vulnificus,chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] comp90820_c0_seq2,474,44.7257,0.56238866,14,3,,3.00E-17,Q3U829,AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5),AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5),GO:0044599; GO:0005737; GO:0000724; GO:0016197; GO:0005730; GO:0005634; GO:0015031,AP-5 adaptor complex; cytoplasm; double-strand break repair via homologous recombination; endosomal transport; nucleolus; nucleus; protein transport,PF14764;,,,,,,,,,AP5Z1_MOUSE,Mus musculus (Mouse),double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031] comp90852_c0_seq1,278,38.4892,0.69256215,1,9,,1.00E-17,Q5SZK8,FRAS1-related extracellular matrix protein 2 (ECM3 homolog),FRAS1-related extracellular matrix protein 2 (ECM3 homolog),GO:0005604; GO:0005509; GO:0007154; GO:0007156; GO:0048839; GO:0016021; GO:0002009; GO:0005886,basement membrane; calcium ion binding; cell communication; homophilic cell adhesion; inner ear development; integral to membrane; morphogenesis of an epithelium; plasma membrane,PF03160;,,,,,,,,,FREM2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009] comp90856_c0_seq1,505,44.7525,1.11665003,254,1134,,,,,,,,,5.00E-48,CHOYP_RNU2.1.1,,,,,,,,, comp90873_c0_seq1,276,52.5362,0.75360492,7,5,,9.00E-08,Q96DM1,PiggyBac transposable element-derived protein 4,PiggyBac transposable element-derived protein 4,,,PF13843;PF13842;,,,,,,,,,PGBD4_HUMAN,Homo sapiens (Human), comp90875_c0_seq1,1327,44.838,0.31659987,51,30,,4.00E-54,Q55GU0,Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1),Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF07714;,4.00E-48,CHOYP_BRAFLDRAFT_119173.1.4,,,,,,,Y9955_DICDI,Dictyostelium discoideum (Slime mold), comp90887_c0_seq1,762,49.6063,0.80937639,0,4,,2.00E-20,Q4A3R3,Deleted in malignant brain tumors 1 protein (Hensin),Deleted in malignant brain tumors 1 protein (Hensin),GO:0030154; GO:0005576; GO:0019898; GO:0016021; GO:0007275; GO:0015031; GO:0005044; GO:0030658; GO:0035375; GO:0042589,cell differentiation; extracellular region; extrinsic to membrane; integral to membrane; multicellular organismal development; protein transport; scavenger receptor activity; transport vesicle membrane; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,,,,,,,,,DMBT1_PIG,Sus scrofa (Pig),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein transport [GO:0015031] comp90887_c0_seq2,795,50.1887,0.8370794,0,5,,2.00E-31,Q5G266,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_TRAPH,Trachypithecus phayrei (Phayre's leaf monkey),exocytosis [GO:0006887] comp90893_c0_seq1,1414,39.8161,0.54645891,90,6,,5.00E-122,Q3MHH0,DDB1- and CUL4-associated factor 12 (WD repeat-containing protein 40A),DDB1- and CUL4-associated factor 12 (WD repeat-containing protein 40A),GO:0080008; GO:0005813; GO:0005737,Cul4-RING ubiquitin ligase complex; centrosome; cytoplasm,,2.00E-58,CHOYP_ISCW_ISCW019533.1.1,,,,,,,DCA12_BOVIN,Bos taurus (Bovine), comp90895_c0_seq1,1200,35.25,0.6991944,1313,6561,,1.00E-14,P53568,CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-BP) (GPE1-binding protein) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1),CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-BP) (GPE1-binding protein) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1),GO:0030183; GO:0006338; GO:0003690; GO:0043353; GO:0001889; GO:0016071; GO:0042267; GO:0043433; GO:0006337; GO:0005634; GO:0045739; GO:0045078; GO:0046982; GO:0042803; GO:0006357; GO:0043565; GO:0008134; GO:0006351,"B cell differentiation; chromatin remodeling; double-stranded DNA binding; enucleate erythrocyte differentiation; liver development; mRNA metabolic process; natural killer cell mediated cytotoxicity; negative regulation of sequence-specific DNA binding transcription factor activity; nucleosome disassembly; nucleus; positive regulation of DNA repair; positive regulation of interferon-gamma biosynthetic process; protein heterodimerization activity; protein homodimerization activity; regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding; transcription factor binding; transcription, DNA-dependent",PF07716;,6.00E-14,CHOYP_LOC100073409.2.2,2.00E-68,ruditapes2_c824,,,,,CEBPG_MOUSE,Mus musculus (Mouse),B cell differentiation [GO:0030183]; chromatin remodeling [GO:0006338]; enucleate erythrocyte differentiation [GO:0043353]; immune response [GO:0006955]; liver development [GO:0001889]; mRNA metabolic process [GO:0016071]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; nucleosome disassembly [GO:0006337]; positive regulation of DNA repair [GO:0045739]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp90911_c0_seq1,213,59.6244,0.98771408,0,14,,2.00E-14,P0A996,Anaerobic glycerol-3-phosphate dehydrogenase subunit C (G-3-P dehydrogenase),Anaerobic glycerol-3-phosphate dehydrogenase subunit C (G-3-P dehydrogenase),GO:0051539; GO:0019563; GO:0046872; GO:0055114; GO:0005886; GO:0006810,"4 iron, 4 sulfur cluster binding; glycerol catabolic process; metal ion binding; oxidation-reduction process; plasma membrane; transport",PF02754;PF13183;,,,,,,,,,GLPC_ECOLI,Escherichia coli (strain K12),anaerobic respiration [GO:0009061]; electron transport chain [GO:0022900]; glycerol catabolic process [GO:0019563]; transport [GO:0006810] comp90914_c0_seq1,359,39.2758,0.44444789,400,3245,,3.00E-13,Q24JV4,UPF0390 protein zgc136864,UPF0390 protein zgc136864,,,PF09495;,,,2.00E-31,ruditapes2_c2188,,,,,U390_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp90933_c0_seq1,419,47.0167,0.55082281,5,0,,4.00E-24,Q62735,Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14),Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14),GO:0003677; GO:0000980; GO:0003705; GO:0001190; GO:0032052; GO:0008206; GO:0038181; GO:0071229; GO:0071417; GO:1902122; GO:0048565; GO:0038185; GO:0070858; GO:0000122; GO:0005719; GO:0005634; GO:0042277; GO:2001250; GO:0045944; GO:0006109; GO:0034255; GO:0009749; GO:0032496; GO:0003707; GO:0004887; GO:0008270,DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; bile acid binding; bile acid metabolic process; bile acid receptor activity; cellular response to acid; cellular response to organonitrogen compound; chenodeoxycholic acid binding; digestive tract development; intracellular bile acid receptor signaling pathway; negative regulation of bile acid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; nuclear euchromatin; nucleus; peptide binding; positive regulation of ammonia assimilation cycle; positive regulation of transcription from RNA polymerase II promoter; regulation of carbohydrate metabolic process; regulation of urea metabolic process; response to glucose stimulus; response to lipopolysaccharide; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,8.00E-45,CHOYP_ECR.1.1,,,,,,,NR1H4_RAT,Rattus norvegicus (Rat),bile acid metabolic process [GO:0008206]; digestive tract development [GO:0048565]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of carbohydrate metabolic process [GO:0006109]; response to glucose [GO:0009749]; response to lipopolysaccharide [GO:0032496] comp90933_c0_seq2,392,44.1327,0.43812994,1,0,,,,,,,,,2.00E-21,CHOYP_ECR.1.1,,,,,,,,, comp90944_c0_seq1,229,62.4454,0.86794108,0,10,,1.00E-22,Q70LM5,Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)],Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)],GO:0017000; GO:0016853; GO:0016874; GO:0031177,antibiotic biosynthetic process; isomerase activity; ligase activity; phosphopantetheine binding,PF00501;PF13193;PF00668;PF00550;,,,,,,,,,LGRC_BREPA,Brevibacillus parabrevis,antibiotic biosynthetic process [GO:0017000] comp90960_c0_seq1,621,38.8084,0.42855285,44,13,,1.00E-14,Q6P2C0,WD repeat-containing protein 93,WD repeat-containing protein 93,GO:0022900; GO:0016651,"electron transport chain; oxidoreductase activity, acting on NAD(P)H",,,,,,,,,,WDR93_HUMAN,Homo sapiens (Human),electron transport chain [GO:0022900] comp90980_c0_seq2,329,34.6505,0.41667052,5,9,,6.00E-16,O43505,"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)","Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)",GO:0008532; GO:0030173; GO:0018146; GO:0030311; GO:0006486,"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; integral to Golgi membrane; keratan sulfate biosynthetic process; poly-N-acetyllactosamine biosynthetic process; protein glycosylation",,,,,,,,,,B3GN1_HUMAN,Homo sapiens (Human),axon guidance [GO:0007411]; keratan sulfate biosynthetic process [GO:0018146]; poly-N-acetyllactosamine biosynthetic process [GO:0030311]; protein O-linked mannosylation [GO:0035269] comp90981_c0_seq1,285,43.1579,0.38012164,2,20,,3.00E-08,Q9UKN7,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,,,,,,,,,MYO15_HUMAN,Homo sapiens (Human),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp90983_c0_seq1,269,41.6357,0.26037004,13,0,,9.00E-32,Q8C0P0,Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L),Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L),GO:0005524; GO:0000086; GO:0051301; GO:0005813; GO:0032154; GO:0005737; GO:0007067; GO:0034048; GO:0005634; GO:0051721; GO:0004674; GO:0051726; GO:0006974,ATP binding; G2/M transition of mitotic cell cycle; cell division; centrosome; cleavage furrow; cytoplasm; mitosis; negative regulation of protein phosphatase type 2A activity; nucleus; protein phosphatase 2A binding; protein serine/threonine kinase activity; regulation of cell cycle; response to DNA damage stimulus,PF00069;,1.00E-20,CHOYP_GWL.1.1,,,,,,,GWL_MOUSE,Mus musculus (Mouse),cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; negative regulation of protein phosphatase type 2A activity [GO:0034048]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle [GO:0051441]; regulation of cell cycle [GO:0051726] comp90996_c0_seq1,344,43.314,0.94781021,2,23,,8.00E-07,Q63226,"Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)","Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)",GO:0030054; GO:0005234; GO:0016021; GO:0004970; GO:0035235; GO:0014069; GO:0045211,cell junction; extracellular-glutamate-gated ion channel activity; integral to membrane; ionotropic glutamate receptor activity; ionotropic glutamate receptor signaling pathway; postsynaptic density; postsynaptic membrane,PF01094;PF00060;PF10613;,,,,,,,,,GRID2_RAT,Rattus norvegicus (Rat),cellular protein localization [GO:0034613]; cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157] comp91004_c0_seq1,807,41.14,0.29597115,18,24,,1.00E-64,Q96S38,Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein),Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein),GO:0005524; GO:0005769; GO:0016020; GO:0035091; GO:0004674; GO:0007165,ATP binding; early endosome; membrane; phosphatidylinositol binding; protein serine/threonine kinase activity; signal transduction,PF04212;PF00069;PF00787;,,,,,,,,,KS6C1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp91009_c0_seq2,503,41.1531,0.84785382,5,16,,,,,,,,,8.00E-14,CHOYP_LOC664189.2.2,,,,,,,,, comp91016_c0_seq1,383,41.2533,0.61568481,8,14,,7.00E-29,P13670,"N,N'-diacetylchitobiase (Chitobiase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)","N,N'-diacetylchitobiase (Chitobiase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)",GO:0004563; GO:0009279; GO:0006032; GO:0030247; GO:0000272,beta-N-acetylhexosaminidase activity; cell outer membrane; chitin catabolic process; polysaccharide binding; polysaccharide catabolic process,PF03173;PF00728;PF02838;,,,,,,,,,CHB_VIBHA,Vibrio harveyi (Beneckea harveyi),chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] comp91025_c0_seq1,206,42.7184,0.32344512,11,5,,2.00E-15,Q99NI4,"Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase)","Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase)",GO:0005524; GO:0032958; GO:0000824; GO:0008440; GO:0000823; GO:0001841; GO:0005634,"ATP binding; inositol phosphate biosynthetic process; inositol tetrakisphosphate 3-kinase activity; inositol-1,4,5-trisphosphate 3-kinase activity; inositol-1,4,5-trisphosphate 6-kinase activity; neural tube formation; nucleus",PF03770;,,,,,,,,,IPMK_RAT,Rattus norvegicus (Rat),inositol phosphate biosynthetic process [GO:0032958]; neural tube formation [GO:0001841] comp91034_c1_seq1,294,45.9184,0.38952915,5,18,,7.00E-13,Q99K67,"Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]","Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]",GO:0019477; GO:0033512; GO:0006091; GO:0005739; GO:0047131; GO:0047130,"L-lysine catabolic process; L-lysine catabolic process to acetyl-CoA via saccharopine; generation of precursor metabolites and energy; mitochondrion; saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity; saccharopine dehydrogenase (NADP+, L-lysine-forming) activity",PF05222;PF16653;PF03435;,,,,,,,,,AASS_MOUSE,Mus musculus (Mouse),generation of precursor metabolites and energy [GO:0006091]; L-lysine catabolic process [GO:0019477]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512] comp91040_c1_seq2,380,51.8421,0.39392332,5,0,,2.00E-24,Q8TD19,Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8),Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8),GO:0005524; GO:0051301; GO:0005829; GO:0046872; GO:0005739; GO:0007067; GO:0007077; GO:0005634; GO:0004674,ATP binding; cell division; cytosol; metal ion binding; mitochondrion; mitosis; mitotic nuclear envelope disassembly; nucleus; protein serine/threonine kinase activity,PF00069;PF00415;,,,,,,,,,NEK9_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; protein phosphorylation [GO:0006468] comp91048_c2_seq1,759,47.8261,0.41552833,16,36,,3.00E-69,Q6PIJ6,F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA),F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA),GO:0005737; GO:0005634,cytoplasm; nucleus,PF00646;,,,,,,,,,FBX38_HUMAN,Homo sapiens (Human),positive regulation of neuron projection development [GO:0010976] comp91050_c0_seq2,755,40.2649,0.50232646,21,119,,4.00E-87,Q9CX00,IST1 homolog,IST1 homolog,GO:0007049; GO:0051301; GO:0016023; GO:0048672,cell cycle; cell division; cytoplasmic membrane-bounded vesicle; positive regulation of collateral sprouting,PF03398;,4.00E-89,CHOYP_LOC100115002.1.1,,,,,,,IST1_MOUSE,Mus musculus (Mouse),abscission [GO:0009838]; cell division [GO:0051301]; cytokinesis [GO:0000910]; establishment of protein localization [GO:0045184]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of proteolysis [GO:0045862]; protein localization [GO:0008104]; protein transport [GO:0015031]; viral capsid secondary envelopment [GO:0046745]; viral release from host cell [GO:0019076]; xenophagy [GO:0098792] comp91067_c0_seq1,244,39.3443,0.63803155,0,20,,4.00E-17,Q80V63,PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4),GO:0003677; GO:0046872; GO:0008168; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; methyltransferase activity; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,PRDM4_MOUSE,Mus musculus (Mouse),"cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp91072_c0_seq1,314,57.0064,0.79970347,0,16,,1.00E-09,Q9RUE8,Probable ABC transporter-binding protein DR_1438,Probable ABC transporter-binding protein DR_1438,GO:0005215,transporter activity,PF01547;,,,,,,,,,UE38_DEIRA,Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422), comp91086_c0_seq1,1263,37.4505,0.66878349,479,5466,,5.00E-39,Q5QJE6,Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2),Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2),GO:0005730; GO:0006355; GO:0006351,"nucleolus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF08698;,3.00E-36,CHOYP_LOC100560380.1.1,6.00E-31,ruditapes_c21075,,,,,TDIF2_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp91101_c0_seq2,582,36.7698,0.31251767,7,64,,,,,,,,,1.00E-11,CHOYP_contig_050111,,,,,,,,, comp91125_c0_seq1,233,40.3433,0.8478417,5,11,,9.00E-18,P30551,Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R),Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R),GO:0031532; GO:0032870; GO:0004951; GO:0007204; GO:0005783; GO:0005768; GO:0001696; GO:0030073; GO:0016021; GO:0005764; GO:0031100; GO:0031016; GO:0030157; GO:0005886; GO:0090274; GO:0002023; GO:0051924; GO:0043266; GO:0051384; GO:0009408; GO:0032496; GO:0007584; GO:0009314; GO:0042594; GO:0001659; GO:0043195,actin cytoskeleton reorganization; cellular response to hormone stimulus; cholecystokinin receptor activity; elevation of cytosolic calcium ion concentration; endoplasmic reticulum; endosome; gastric acid secretion; insulin secretion; integral to membrane; lysosome; organ regeneration; pancreas development; pancreatic juice secretion; plasma membrane; positive regulation of somatostatin secretion; reduction of food intake in response to dietary excess; regulation of calcium ion transport; regulation of potassium ion transport; response to glucocorticoid stimulus; response to heat; response to lipopolysaccharide; response to nutrient; response to radiation; response to starvation; temperature homeostasis; terminal bouton,PF00001;PF09193;,,,,,,,,,CCKAR_RAT,Rattus norvegicus (Rat),actin cytoskeleton reorganization [GO:0031532]; cellular response to hormone stimulus [GO:0032870]; eating behavior [GO:0042755]; feeding behavior [GO:0007631]; gastric acid secretion [GO:0001696]; insulin secretion [GO:0030073]; organ regeneration [GO:0031100]; pancreas development [GO:0031016]; pancreatic juice secretion [GO:0030157]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of somatostatin secretion [GO:0090274]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of calcium ion transport [GO:0051924]; regulation of hormone secretion [GO:0046883]; regulation of potassium ion transport [GO:0043266]; response to glucocorticoid [GO:0051384]; response to heat [GO:0009408]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to radiation [GO:0009314]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; temperature homeostasis [GO:0001659] comp9113_c0_seq1,402,38.5572,0.87844273,14,0,,7.00E-44,P91766,Acetylcholine receptor subunit alpha-like (MARA1),Acetylcholine receptor subunit alpha-like (MARA1),GO:0004889; GO:0030054; GO:0016021; GO:0045211,acetylcholine-activated cation-selective channel activity; cell junction; integral to membrane; postsynaptic membrane,PF02931;PF02932;,4.00E-54,CHOYP_LOC100533249.1.1,,,,,,,ACH1_MANSE,Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm), comp91141_c0_seq1,1007,46.8719,0.65352055,51,10,,4.00E-89,Q9ESJ0,Exportin-4 (Exp4),Exportin-4 (Exp4),GO:0005737; GO:0005634; GO:0046827; GO:0015031,cytoplasm; nucleus; positive regulation of protein export from nucleus; protein transport,PF08767;,5.00E-26,CHOYP_XPO4.1.1,,,,,,,XPO4_MOUSE,Mus musculus (Mouse),positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611] comp91147_c0_seq1,414,37.9227,0.33685261,10,21,,8.00E-15,Q5R8Z6,Multiple coagulation factor deficiency protein 2 homolog,Multiple coagulation factor deficiency protein 2 homolog,GO:0005794; GO:0005509; GO:0005783; GO:0005793; GO:0015031; GO:0016192,Golgi apparatus; calcium ion binding; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; protein transport; vesicle-mediated transport,PF13499;,1.00E-30,CHOYP_DPSE_GA30097.1.1,,,,,,,MCFD2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] comp91158_c0_seq1,289,41.1765,0.98640637,3,13,,,,,,,,,5.00E-14,CHOYP_LOC100378936.1.1,,,,,,,,, comp91167_c0_seq1,453,44.1501,0.27573775,21,14,,8.00E-23,Q5T011,Protein SZT2 (Seizure threshold 2 protein homolog),Protein SZT2 (Seizure threshold 2 protein homolog),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,8.00E-20,CHOYP_SZT2.1.1,,,,,,,SZT2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp91170_c0_seq1,221,32.5792,0.3468821,3,8,,1.00E-08,Q1DDZ9,UPF0061 protein MXAN_0863,UPF0061 protein MXAN_0863,,,PF02696;,,,,,,,,,Y863_MYXXD,Myxococcus xanthus (strain DK 1622), comp91170_c1_seq1,507,33.1361,0.21610975,10,20,,8.00E-06,A3NW79,UPF0061 protein BURPS1106A_2336,UPF0061 protein BURPS1106A_2336,,,PF02696;,,,,,,,,,Y2336_BURP0,Burkholderia pseudomallei (strain 1106a), comp91185_c0_seq1,445,43.3708,0.14480593,16,16,,6.00E-34,Q9JK91,DNA mismatch repair protein Mlh1 (MutL protein homolog 1),DNA mismatch repair protein Mlh1 (MutL protein homolog 1),GO:0005524; GO:0016887; GO:0032389; GO:0032390; GO:0032407; GO:0005712; GO:0006303; GO:0032137; GO:0008630; GO:0045190; GO:0001673; GO:0007060; GO:0043060; GO:0006298; GO:0045950; GO:0000289; GO:0005654; GO:0048477; GO:0000712; GO:0003697; GO:0016446; GO:0007283; GO:0051257; GO:0007129; GO:0000795,ATP binding; ATPase activity; MutLalpha complex; MutLbeta complex; MutSalpha complex binding; chiasma; double-strand break repair via nonhomologous end joining; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; male germ cell nucleus; male meiosis chromosome segregation; meiotic metaphase I plate congression; mismatch repair; negative regulation of mitotic recombination; nuclear-transcribed mRNA poly(A) tail shortening; nucleoplasm; oogenesis; resolution of meiotic recombination intermediates; single-stranded DNA binding; somatic hypermutation of immunoglobulin genes; spermatogenesis; spindle midzone assembly involved in meiosis; synapsis; synaptonemal complex,PF01119;PF16413;,2.00E-15,CHOYP_MLH1.1.1,,,,,,,MLH1_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome segregation [GO:0045143]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis [GO:0007140]; male meiosis chromosome segregation [GO:0007060]; meiotic chromosome segregation [GO:0045132]; meiotic metaphase I plate congression [GO:0043060]; meiotic nuclear division [GO:0007126]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp91186_c0_seq1,428,41.1215,0.51350194,19,12,,6.00E-46,Q8K449,ATP-binding cassette sub-family A member 9,ATP-binding cassette sub-family A member 9,GO:0005524; GO:0006200; GO:0016887; GO:0016021; GO:0005739; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; integral to membrane; mitochondrion; transport,PF00005;,6.00E-46,CHOYP_TRIADDRAFT_53677.1.1,,,,,,,ABCA9_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869] comp91204_c0_seq1,565,48.6726,0.88791796,44,0,,4.00E-55,Q6GQ29,Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase),Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase),GO:0005794; GO:0004180; GO:0005783; GO:0005615; GO:0005764; GO:0046872; GO:0070573; GO:0043171; GO:0042803; GO:0006508,Golgi apparatus; carboxypeptidase activity; endoplasmic reticulum; extracellular space; lysosome; metal ion binding; metallodipeptidase activity; peptide catabolic process; protein homodimerization activity; proteolysis,PF04389;,3.00E-19,CHOYP_CBPQ.1.1,,,,,,,CBPQ_XENLA,Xenopus laevis (African clawed frog),peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp91205_c0_seq1,540,45.9259,0.83314648,4,30,,9.00E-38,P51906,Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1),Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1),GO:0070779; GO:0051938; GO:0016595; GO:0015501; GO:0016021; GO:0005886; GO:0051260; GO:0017153,D-aspartate import; L-glutamate import; glutamate binding; glutamate:sodium symporter activity; integral to membrane; plasma membrane; protein homooligomerization; sodium:dicarboxylate symporter activity,PF00375;,,,,,,,,,EAA3_MOUSE,Mus musculus (Mouse),cysteine transport [GO:0042883]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260] comp91207_c1_seq1,276,47.1014,0.97708514,0,16,,3.00E-07,Q99K41,EMILIN-1 (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1),EMILIN-1 (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1),GO:0007155; GO:0005581; GO:0030023; GO:0030198; GO:0070062; GO:0042802; GO:0010811; GO:0005578,cell adhesion; collagen; extracellular matrix constituent conferring elasticity; extracellular matrix organization; extracellular vesicular exosome; identical protein binding; positive regulation of cell-substrate adhesion; proteinaceous extracellular matrix,PF00386;PF01391;PF07546;,,,,,,,,,EMIL1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811] comp91218_c0_seq1,471,39.9151,0.53472542,13,14,,4.00E-30,Q6EBV9,Autophagy-related protein 9B (APG9-like 2) (Nitric oxide synthase 3-overlapping antisense gene protein),Autophagy-related protein 9B (APG9-like 2) (Nitric oxide synthase 3-overlapping antisense gene protein),GO:0005776; GO:0000045; GO:0000421; GO:0031410; GO:0016021,autophagic vacuole; autophagic vacuole assembly; autophagic vacuole membrane; cytoplasmic vesicle; integral to membrane,PF04109;,5.00E-22,CHOYP_LOC100561934.1.1,,,,,,,ATG9B_MOUSE,Mus musculus (Mouse),autophagosome assembly [GO:0000045]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein localization to pre-autophagosomal structure [GO:0034497] comp91236_c0_seq1,415,46.0241,0.13714365,3,16,,8.00E-59,Q8VHE6,"Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)","Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-85,CHOYP_DNAH5.2.2,,,,,,,DYH5_MOUSE,Mus musculus (Mouse),cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317] comp91236_c1_seq1,335,47.1642,0.27357352,4,10,,5.00E-29,Q39575,"Dynein gamma chain, flagellar outer arm","Dynein gamma chain, flagellar outer arm",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,7.00E-63,CHOYP_LOC577371.1.2,,,,,,,DYHG_CHLRE,Chlamydomonas reinhardtii (Chlamydomonas smithii),cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158] comp91251_c0_seq1,725,39.7241,1.19246604,1967,7949,,2.00E-45,P79382,Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I),Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I),GO:0005783; GO:0005789; GO:0004364; GO:0016021; GO:0005741; GO:0070207,endoplasmic reticulum; endoplasmic reticulum membrane; glutathione transferase activity; integral to membrane; mitochondrial outer membrane; protein homotrimerization,PF01124;,,,2.00E-15,ruditapes_c6317,,,,,MGST1_PIG,Sus scrofa (Pig),protein homotrimerization [GO:0070207] comp91253_c0_seq1,460,39.1304,0.75822727,8,33,,2.00E-23,A1A4M6,StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5),StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5),GO:0008289; GO:0006869,lipid binding; lipid transport,PF01852;,5.00E-29,CHOYP_STAR5.2.2,,,,,,,STAR5_BOVIN,Bos taurus (Bovine),lipid transport [GO:0006869] comp91259_c1_seq1,537,37.4302,0.31979505,7,6,,2.00E-31,Q0P6H9,Transmembrane protein 62,Transmembrane protein 62,GO:0016021,integral to membrane,PF00149;,,,,,,,,,TMM62_HUMAN,Homo sapiens (Human), comp91265_c0_seq1,365,38.3562,0.77806706,9,19,,1.00E-07,Q0IES7,Protein mab-21-like,Protein mab-21-like,GO:0048568,embryonic organ development,PF03281;,,,,,,,,,MB21L_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti), comp91266_c0_seq1,930,31.9355,0.42430092,3092,4045,,2.00E-25,Q02370,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit),NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit),GO:0005747; GO:0055114,mitochondrial respiratory chain complex I; oxidation-reduction process,PF05047;,,,2.00E-41,ruditapes2_c940,,,,,NDUA2_BOVIN,Bos taurus (Bovine),oxidation-reduction process [GO:0055114] comp91280_c0_seq1,726,44.3526,0.65072508,21,48,,2.00E-36,Q8BGQ7,"Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)","Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)",GO:0005524; GO:0004813; GO:0006419; GO:0016597; GO:0002161; GO:0021680; GO:0005737; GO:0030968; GO:0001942; GO:0046872; GO:0043524; GO:0050885; GO:0006457; GO:0043200; GO:0000049; GO:0006400,ATP binding; alanine-tRNA ligase activity; alanyl-tRNA aminoacylation; amino acid binding; aminoacyl-tRNA editing activity; cerebellar Purkinje cell layer development; cytoplasm; endoplasmic reticulum unfolded protein response; hair follicle development; metal ion binding; negative regulation of neuron apoptotic process; neuromuscular process controlling balance; protein folding; response to amino acid stimulus; tRNA binding; tRNA modification,PF02272;PF01411;PF07973;,,,,,,,,,SYAC_MOUSE,Mus musculus (Mouse),alanyl-tRNA aminoacylation [GO:0006419]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; endoplasmic reticulum unfolded protein response [GO:0030968]; hair follicle development [GO:0001942]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; protein folding [GO:0006457]; response to amino acid [GO:0043200]; skin development [GO:0043588]; tRNA modification [GO:0006400] comp91297_c1_seq1,461,48.3731,0.63853959,28,15,,3.00E-67,Q8N5D0,WD and tetratricopeptide repeats protein 1,WD and tetratricopeptide repeats protein 1,GO:0055082; GO:0032869; GO:0005829; GO:0004857; GO:0006006; GO:0001701; GO:0043231; GO:0035264; GO:0045717; GO:0000122; GO:0005634; GO:0008361,cellular chemical homeostasis; cellular response to insulin stimulus; cytosol; enzyme inhibitor activity; glucose metabolic process; in utero embryonic development; intracellular membrane-bounded organelle; multicellular organism growth; negative regulation of fatty acid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of cell size,PF00400;,3.00E-82,CHOYP_BRAFLDRAFT_74529.1.1,,,,,,,WDTC1_HUMAN,Homo sapiens (Human),cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361] comp91306_c0_seq1,201,52.7363,0.72559267,0,5,,7.00E-16,P77783,Probable dimethyl sulfoxide reductase chain YnfF (DMSO reductase) (EC 1.8.99.-),Probable dimethyl sulfoxide reductase chain YnfF (DMSO reductase) (EC 1.8.99.-),GO:0051539; GO:0045333; GO:0009389; GO:0009055; GO:0016020; GO:0030151; GO:0005886; GO:0033797,"4 iron, 4 sulfur cluster binding; cellular respiration; dimethyl sulfoxide reductase activity; electron carrier activity; membrane; molybdenum ion binding; plasma membrane; selenate reductase activity",PF04879;PF00384;PF01568;,,,,,,,,,YNFF_ECOLI,Escherichia coli (strain K12), comp91308_c0_seq1,661,42.5113,0.8800511,5,39,,2.00E-39,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,9.00E-15,CHOYP_HSPA12A.12.27,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp91317_c0_seq2,350,46,0.54930026,4,0,,2.00E-07,Q54KA7,"Ankyrin repeat, PH and SEC7 domain containing protein secG","Ankyrin repeat, PH and SEC7 domain containing protein secG",GO:0005086; GO:0031589; GO:0006935; GO:0005829; GO:0005764; GO:0005543; GO:0032012,ARF guanyl-nucleotide exchange factor activity; cell-substrate adhesion; chemotaxis; cytosol; lysosome; phospholipid binding; regulation of ARF protein signal transduction,PF00023;PF12796;PF00169;PF01369;,,,,,,,,,SECG_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012] comp91324_c0_seq1,214,56.5421,1.06613898,0,8,,9.00E-10,Q6A7M3,Ribosome maturation factor RimP,Ribosome maturation factor RimP,GO:0005737; GO:0042254,cytoplasm; ribosome biogenesis,PF02576;,,,,,,,,,RIMP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),ribosomal small subunit biogenesis [GO:0042274] comp91327_c1_seq1,275,44.3636,0.15333536,9,7,,6.00E-07,P01266,Thyroglobulin (Tg),Thyroglobulin (Tg),GO:0005615; GO:0042446; GO:0015705; GO:0031641; GO:0007165; GO:0030878; GO:0006590,extracellular space; hormone biosynthetic process; iodide transport; regulation of myelination; signal transduction; thyroid gland development; thyroid hormone generation,PF00135;PF07699;PF00086;,,,,,,,,,THYG_HUMAN,Homo sapiens (Human),hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; transcytosis [GO:0045056] comp91331_c0_seq1,575,47.6522,0.65032455,8900,1,male>female,4.00E-18,P22975,Sperm-specific protein PL-I (PL-I) (Sperm-specific linker histone H1-like protein) (Fragment),Sperm-specific protein PL-I (PL-I) (Sperm-specific linker histone H1-like protein) (Fragment),GO:0003677; GO:0030154; GO:0030261; GO:0007275; GO:0000786; GO:0006334; GO:0005634; GO:0007283,DNA binding; cell differentiation; chromosome condensation; multicellular organismal development; nucleosome; nucleosome assembly; nucleus; spermatogenesis,PF00538;,,,,,,,,,H1L_SPISO,Spisula solidissima (Atlantic surf-clam),cell differentiation [GO:0030154]; chromosome condensation [GO:0030261]; multicellular organism development [GO:0007275]; nucleosome assembly [GO:0006334]; spermatogenesis [GO:0007283] comp91334_c0_seq1,663,40.5732,0.73581728,6,0,,1.00E-09,Q1L673,"Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)","Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)",GO:0008434; GO:0005634; GO:0043565; GO:0003707; GO:0070561; GO:0008270,calcitriol receptor activity; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; vitamin D receptor signaling pathway; zinc ion binding,PF00104;PF00105;,,,,,,,,,VDRB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"heart jogging [GO:0003146]; heart looping [GO:0001947]; transcription, DNA-templated [GO:0006351]" comp91334_c0_seq2,617,40.8428,0.74528917,0,3,,8.00E-10,Q1L673,"Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)","Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)",GO:0008434; GO:0005634; GO:0043565; GO:0003707; GO:0070561; GO:0008270,calcitriol receptor activity; nucleus; sequence-specific DNA binding; steroid hormone receptor activity; vitamin D receptor signaling pathway; zinc ion binding,PF00104;PF00105;,,,,,,,,,VDRB_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"heart jogging [GO:0003146]; heart looping [GO:0001947]; transcription, DNA-templated [GO:0006351]" comp91334_c1_seq1,356,42.4157,0.50123246,10,3,,6.00E-06,P68306,Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2),Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2),GO:0005634; GO:0043565; GO:0003707; GO:0070324; GO:0004887; GO:0008270,nucleus; sequence-specific DNA binding; steroid hormone receptor activity; thyroid hormone binding; thyroid hormone receptor activity; zinc ion binding,PF00104;PF00105;,2.00E-13,CHOYP_HR96.1.1,,,,,,,THB_CHICK,Gallus gallus (Chicken),"female courtship behavior [GO:0008050]; negative regulation of female receptivity [GO:0007621]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; organ morphogenesis [GO:0009887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart contraction [GO:0008016]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; Type I pneumocyte differentiation [GO:0060509]" comp91349_c0_seq1,329,60.4863,1.20146741,1,10,,3.00E-69,Q6A6L5,Elongation factor G (EF-G),Elongation factor G (EF-G),GO:0005525; GO:0006184; GO:0003924; GO:0005737; GO:0003746,GTP binding; GTP catabolic process; GTPase activity; cytoplasm; translation elongation factor activity,PF00679;PF14492;PF03764;PF03144;,,,,,,,,,EFG_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp91361_c0_seq1,1150,43.3043,0.37966779,1,6,,9.00E-36,Q01968,Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein),Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein),GO:0005795; GO:0005798; GO:0030675; GO:0042384; GO:0030136; GO:0005905; GO:0005829; GO:0005769; GO:0031901; GO:0001701; GO:0043647; GO:0052745; GO:0005634; GO:0030670; GO:0006661; GO:0046856; GO:0004439; GO:0001750; GO:0005886; GO:0032314; GO:0007264; GO:0005802,"Golgi stack; Golgi-associated vesicle; Rac GTPase activator activity; cilium assembly; clathrin-coated vesicle; coated pit; cytosol; early endosome; early endosome membrane; in utero embryonic development; inositol phosphate metabolic process; inositol phosphate phosphatase activity; nucleus; phagocytic vesicle membrane; phosphatidylinositol biosynthetic process; phosphatidylinositol dephosphorylation; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; photoreceptor outer segment; plasma membrane; regulation of Rac GTPase activity; small GTPase mediated signal transduction; trans-Golgi network",PF03372;PF16726;PF00620;,2.00E-14,CHOYP_LOC101170302.1.1,,,,,,,OCRL_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp91396_c0_seq1,335,43.5821,0.7617676,2,13,,2.00E-10,Q6NRD5,Exonuclease 3'-5' domain-containing protein 1 (Exonuclease 3'-5' domain-like-containing protein 1),piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1),GO:0008408; GO:0003676; GO:0090305,3'-5' exonuclease activity; nucleic acid binding; nucleic acid phosphodiester bond hydrolysis,PF01612;,8.00E-12,CHOYP_EGL.2.3,,,,,,,EXD1_XENLA,Xenopus laevis (African clawed frog),gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587] comp91397_c0_seq2,404,39.3564,0.44900497,2,0,,,,,,,,,,,3.00E-22,ruditapes_c24899,,,,,,, comp91405_c0_seq1,264,65.1515,1.46168672,0,13,,1.00E-44,Q06734,Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase),Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase),GO:0005524; GO:0006526; GO:0004055; GO:0005737,ATP binding; arginine biosynthetic process; argininosuccinate synthase activity; cytoplasm,PF00764;,,,,,,,,,ASSY_STRLA,Streptomyces lavendulae,arginine biosynthetic process [GO:0006526] comp91409_c0_seq1,206,61.165,1.20078492,71,22,,,,,,,,,2.00E-79,CHOYP_LOC100353582.2.2,,,,,,,,, comp91423_c0_seq1,224,60.2679,1.05801482,0,22,,3.00E-45,Q6A9C3,L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27),L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27),GO:0004459; GO:0044262; GO:0005737; GO:0006096,L-lactate dehydrogenase activity; cellular carbohydrate metabolic process; cytoplasm; glycolysis,PF02866;PF00056;,,,,,,,,,LDH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glycolytic process [GO:0006096] comp91437_c0_seq1,569,43.9367,1.3817108,4,36,,2.00E-11,Q29143,Early lactation protein,Early lactation protein,GO:0005576; GO:0007595; GO:0004867,extracellular region; lactation; serine-type endopeptidase inhibitor activity,PF00014;,,,,,,,,,ELAC_TRIVU,Trichosurus vulpecula (Brush-tailed possum),lactation [GO:0007595] comp91440_c0_seq1,230,58.6957,1.14307154,0,12,,3.00E-32,Q6A7W9,Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase) (EC 2.7.1.23),NAD kinase (EC 2.7.1.23) (ATP-dependent NAD kinase),GO:0005524; GO:0019674; GO:0003951; GO:0006741; GO:0005737; GO:0046872,ATP binding; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; cytoplasm; metal ion binding,PF01513;,,,,,,,,,PPNK_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741] comp91458_c0_seq1,304,47.6974,0.06044457,2,4,,4.00E-29,Q8N0W3,L-fucose kinase (Fucokinase) (EC 2.7.1.52),L-fucose kinase (Fucokinase) (EC 2.7.1.52),GO:0005524; GO:0005737; GO:0050201,ATP binding; cytoplasm; fucokinase activity,PF07959;PF08544;PF00288;,2.00E-44,CHOYP_FUK.1.1,,,,,,,FUK_HUMAN,Homo sapiens (Human), comp91468_c0_seq1,368,39.1304,0.72581181,9,22,,5.00E-15,C0LGI2,Probable LRR receptor-like serine/threonine-protein kinase At1g67720 (EC 2.7.11.1),Probable LRR receptor-like serine/threonine-protein kinase At1g67720 (EC 2.7.11.1),GO:0005524; GO:0016021; GO:0004674,ATP binding; integral to membrane; protein serine/threonine kinase activity,PF12819;PF07714;,,,,,,,,,Y1677_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp91470_c0_seq1,722,38.9197,0.43996028,28,50,,,,,,,,,8.00E-16,CHOYP_BRAFLDRAFT_115379.1.1,,,,,,,,, comp91470_c1_seq1,242,38.843,0.35303266,9,0,,9.00E-35,O75908,Sterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2),Sterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2),GO:0005903; GO:0034736; GO:0015485; GO:0033344; GO:0034435; GO:0042632; GO:0008203; GO:0005789; GO:0000062; GO:0016021; GO:0030299; GO:0010742; GO:0034379,brush border; cholesterol O-acyltransferase activity; cholesterol binding; cholesterol efflux; cholesterol esterification; cholesterol homeostasis; cholesterol metabolic process; endoplasmic reticulum membrane; fatty-acyl-CoA binding; integral to membrane; intestinal cholesterol absorption; macrophage derived foam cell differentiation; very-low-density lipoprotein particle assembly,PF03062;,7.00E-36,CHOYP_LOC100716750.1.1,,,,,,,SOAT2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; intestinal cholesterol absorption [GO:0030299]; macrophage derived foam cell differentiation [GO:0010742]; very-low-density lipoprotein particle assembly [GO:0034379] comp91476_c0_seq1,288,35.4167,0.84117438,9,12,,,,,,,,,5.00E-13,CHOYP_LOC578054.5.7,,,,,,,,, comp91481_c0_seq1,352,38.6364,0.56172311,6,7,,2.00E-74,P53361,TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit),TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit),GO:0003677; GO:0006352; GO:0005634,"DNA binding; DNA-dependent transcription, initiation; nucleus",PF00352;,5.00E-65,CHOYP_TBP.1.1,,,,,,,TBP_SPOFR,Spodoptera frugiperda (Fall armyworm),"DNA-templated transcription, initiation [GO:0006352]" comp91482_c0_seq1,1875,41.7067,0.77453624,1468,9368,,1.00E-20,Q8NFZ5,TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein),TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein),GO:0023035; GO:0007249; GO:0006915; GO:0071222; GO:0005829; GO:0006954; GO:0070498; GO:2000352; GO:0005634; GO:0031593; GO:0050871; GO:0043123; GO:0043032; GO:0045944; GO:0019901; GO:0050821; GO:0034134; GO:0034138; GO:0034162; GO:0006351,"CD40 signaling pathway; I-kappaB kinase/NF-kappaB cascade; apoptotic process; cellular response to lipopolysaccharide; cytosol; inflammatory response; interleukin-1-mediated signaling pathway; negative regulation of endothelial cell apoptotic process; nucleus; polyubiquitin binding; positive regulation of B cell activation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of macrophage activation; positive regulation of transcription from RNA polymerase II promoter; protein kinase binding; protein stabilization; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 9 signaling pathway; transcription, DNA-dependent",PF12180;,,,,,,,,,TNIP2_HUMAN,Homo sapiens (Human),"apoptotic process [GO:0006915]; CD40 signaling pathway [GO:0023035]; cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of endothelial cell apoptotic process [GO:2000352]; positive regulation of B cell activation [GO:0050871]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage activation [GO:0043032]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 9 signaling pathway [GO:0034162]; transcription, DNA-templated [GO:0006351]" comp91485_c0_seq1,504,48.6111,0.61435765,33,7,,,,,,,,,3.00E-20,CHOYP_BMBL.1.1,,,,,,,,, comp91488_c0_seq2,1910,33.8743,0.49716728,491,1710,,1.00E-119,O73817,Proteasome subunit beta type-3 (EC 3.4.25.1) (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain),Proteasome subunit beta type-3 (EC 3.4.25.1) (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain),GO:0005737; GO:0005634; GO:0005839; GO:0051603; GO:0004298,cytoplasm; nucleus; proteasome core complex; proteolysis involved in cellular protein catabolic process; threonine-type endopeptidase activity,PF00227;,6.00E-73,CHOYP_BRAFLDRAFT_281217.1.1,1.00E-174,ruditapes_c7354,3.00E-73,AM864330.p.cg.6,8,,PSB3_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),proteolysis involved in cellular protein catabolic process [GO:0051603] comp91515_c1_seq1,343,38.7755,0.32453106,11,28,,3.00E-06,Q5M7P6,Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-),GO:0005524; GO:0005576; GO:0004674,ATP binding; extracellular region; protein serine/threonine kinase activity,PF03109;,,,,,,,,,ADCK1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp91520_c0_seq1,436,57.1101,0.99383239,1,19,,2.00E-42,P50216,Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase),GO:0006097; GO:0004450; GO:0046872; GO:0006099,glyoxylate cycle; isocitrate dehydrogenase (NADP+) activity; metal ion binding; tricarboxylic acid cycle,PF03971;,,,,,,,,,IDH_CORGL,Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025),glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] comp91523_c0_seq1,1021,39.4711,0.90777289,1140,8644,,7.00E-67,Q9BEA9,Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3),Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3),GO:0005737; GO:0006749; GO:0004364,cytoplasm; glutathione metabolic process; glutathione transferase activity,PF00043;PF02798;,8.00E-24,CHOYP_BRAFLDRAFT_72748.1.1,2.00E-79,ruditapes2_c352,,,,,GSTM3_MACFU,Macaca fuscata fuscata (Japanese macaque),glutathione metabolic process [GO:0006749] comp91529_c0_seq1,622,41.4791,0.71652728,11,22,,2.00E-88,Q61831,Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3),Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3),GO:0005524; GO:0004705; GO:0005739; GO:0005634; GO:0005886,ATP binding; JUN kinase activity; mitochondrion; nucleus; plasma membrane,PF00069;,4.00E-89,CHOYP_JNK.1.1,,,,,,,MK10_MOUSE,Mus musculus (Mouse),JNK cascade [GO:0007254]; locomotor rhythm [GO:0045475]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; response to light stimulus [GO:0009416] comp91541_c0_seq1,951,44.9001,0.33697661,41,26,,3.00E-13,Q80Z37,E3 ubiquitin-protein ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3),E3 ubiquitin-protein ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3),GO:0003677; GO:0016605; GO:0019789; GO:0003823; GO:0005814; GO:0036064; GO:0000930; GO:0042771; GO:0051457; GO:0016607; GO:0032391; GO:0045893; GO:0051443; GO:0043161; GO:0070936; GO:0034504; GO:0006513; GO:0016925; GO:0042127; GO:0000922; GO:0004842; GO:0008270,"DNA binding; PML body; SUMO ligase activity; antigen binding; centriole; cilium basal body; gamma-tubulin complex; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; maintenance of protein location in nucleus; nuclear speck; photoreceptor connecting cilium; positive regulation of transcription, DNA-dependent; positive regulation of ubiquitin-protein ligase activity; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein localization to nucleus; protein monoubiquitination; protein sumoylation; regulation of cell proliferation; spindle pole; ubiquitin-protein ligase activity; zinc ion binding",,,,,,,,,,TOPRS_MOUSE,Mus musculus (Mouse),"cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein localization to nucleus [GO:0034504]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of cell proliferation [GO:0042127]; ubiquitin-dependent protein catabolic process [GO:0006511]" comp91551_c0_seq1,356,40.4494,0.4897158,5,27,,5.00E-29,Q5U247,Exocyst complex component 8,Exocyst complex component 8,GO:0005737; GO:0006887; GO:0005543; GO:0015031,cytoplasm; exocytosis; phospholipid binding; protein transport,PF16528;,,,,,,,,,EXOC8_XENLA,Xenopus laevis (African clawed frog),exocytosis [GO:0006887]; protein transport [GO:0015031] comp91553_c0_seq1,219,39.726,0.50001043,0,6,,1.00E-06,P31843,RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog),RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog),GO:0003723; GO:0006278; GO:0003964; GO:0003968; GO:0005739,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; RNA-directed RNA polymerase activity; mitochondrion,PF00078;,,,,,,,,,RRPO_OENBE,Oenothera berteroana (Bertero's evening primrose), comp91555_c0_seq1,421,47.981,0.50039808,16,0,,3.00E-18,Q80U22,Iporin (Interacting protein of Rab1) (RUN and SH3 domain-containing protein 2),Iporin (Interacting protein of Rab1) (RUN and SH3 domain-containing protein 2),GO:0005829,cytosol,PF02759;PF14604;,,,,,,,,,RUSC2_MOUSE,Mus musculus (Mouse), comp91624_c0_seq1,232,46.5517,0.96183418,0,13,,1.00E-09,P35448,Thrombospondin-1,Thrombospondin-1,GO:0005509; GO:0007155; GO:0005576; GO:0008201; GO:0016529,calcium ion binding; cell adhesion; extracellular region; heparin binding; sarcoplasmic reticulum,PF12947;PF00090;PF02412;PF05735;PF00093;,,,,,,,,,TSP1_XENLA,Xenopus laevis (African clawed frog),cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; response to unfolded protein [GO:0006986] comp91639_c0_seq1,400,52.25,0.77513371,7,5,,,,,,,,,8.00E-13,CHOYP_LOC100163621.2.2,,,,,,,,, comp91655_c0_seq1,410,42.9268,0.48524492,5,21,,2.00E-33,Q07646,Mesoderm-specific transcript protein (EC 3.-.-.-) (Paternally-expressed gene 1 protein),Mesoderm-specific transcript protein (EC 3.-.-.-) (Paternally-expressed gene 1 protein),GO:0005783; GO:0005789; GO:0016787; GO:0016021; GO:0008152; GO:0010883; GO:0032526,endoplasmic reticulum; endoplasmic reticulum membrane; hydrolase activity; integral to membrane; metabolic process; regulation of lipid storage; response to retinoic acid,PF00561;,,,,,,,,,MEST_MOUSE,Mus musculus (Mouse),mesoderm development [GO:0007498]; regulation of lipid storage [GO:0010883]; response to retinoic acid [GO:0032526] comp91664_c0_seq1,253,51.7787,1.09958428,13,121,,9.00E-09,Q6CQE5,Protein TAR1,Protein TAR1,GO:0005739,mitochondrion,,2.00E-17,CHOYP_LOC100214376.1.1,,,,,,,TAR1_KLULA,Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica), comp91667_c0_seq1,553,41.0488,0.43533067,32,0,,3.00E-68,Q80YA3,Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1),Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1),GO:0005737; GO:0016787; GO:0016042; GO:0046872,cytoplasm; hydrolase activity; lipid catabolic process; metal ion binding,PF02862;,4.00E-69,CHOYP_DDHD1.1.1,,,,,,,DDHD1_MOUSE,Mus musculus (Mouse),lipid catabolic process [GO:0016042]; positive regulation of mitochondrial fission [GO:0090141]; sperm mitochondrion organization [GO:0030382] comp91679_c0_seq1,518,41.8919,0.57755737,1331,4848,,3.00E-46,Q6DBT3,Thioredoxin domain-containing protein 17 (Thioredoxin-like protein 5),Thioredoxin domain-containing protein 17 (Thioredoxin-like protein 5),GO:0005737,cytoplasm,PF06110;,5.00E-23,CHOYP_LOC100755189.1.1,1.00E-35,ruditapes_c3082,,,,,TXD17_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp9167_c0_seq1,208,52.8846,0.38384726,4,0,,,,,,,,,,,1.00E-16,ruditapes2_lrc3006,,,,,,, comp91689_c0_seq1,333,42.3423,0.60998927,9,0,,,,,,,,,2.00E-18,CHOYP_LOC100489553.10.14,,,,,,,,, comp91695_c1_seq1,314,45.2229,0.76830048,15,10,,7.00E-39,Q7ZVG6,E3 ubiquitin-protein ligase Siah1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1),E3 ubiquitin-protein ligase Siah1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1),GO:0005829; GO:0007275; GO:0051402; GO:0005634; GO:0043161; GO:0042787; GO:0004842; GO:0008270,cytosol; multicellular organismal development; neuron apoptotic process; nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF03145;,3.00E-74,CHOYP_LOC100555807.1.1,,,,,,,SIAH1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; neuron apoptotic process [GO:0051402]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp91701_c0_seq1,374,45.4545,0.37202647,0,0,,2.00E-17,Q9BRI3,Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),GO:0008324; GO:0016021; GO:0005770; GO:0005765; GO:0061090; GO:0055085; GO:0006829,cation transmembrane transporter activity; integral to membrane; late endosome; lysosomal membrane; positive regulation of sequestering of zinc ion; transmembrane transport; zinc ion transport,PF01545;,2.00E-14,CHOYP_LOC100178917.1.1,,,,,,,ZNT2_HUMAN,Homo sapiens (Human),positive regulation of sequestering of zinc ion [GO:0061090]; response to zinc ion [GO:0010043] comp91701_c0_seq2,845,43.0769,0.53909953,15,16,,3.00E-49,Q2HJ10,Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2),GO:0008324; GO:0016021; GO:0005774; GO:0006829,cation transmembrane transporter activity; integral to membrane; vacuolar membrane; zinc ion transport,PF01545;,3.00E-15,CHOYP_LOC100123888.1.1,,,,,,,ZNT2_MOUSE,Mus musculus (Mouse),positive regulation of sequestering of zinc ion [GO:0061090]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043] comp91711_c0_seq1,486,46.9136,0.38226221,12,33,,2.00E-67,Q6DKP5,WD repeat-containing protein 13,WD repeat-containing protein 13,GO:0005634,nucleus,PF00400;,7.00E-59,CHOYP_WDR13.1.1,,,,,,,WDR13_PANTR,Pan troglodytes (Chimpanzee), comp91740_c0_seq1,482,44.1909,0.51192589,18,14,,2.00E-15,P50748,Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod),GO:0051301; GO:0000777; GO:0005829; GO:0005828; GO:0007067; GO:0000278; GO:0007093; GO:0005634; GO:0006461; GO:0007096; GO:0000922,cell division; condensed chromosome kinetochore; cytosol; kinetochore microtubule; mitosis; mitotic cell cycle; mitotic cell cycle checkpoint; nucleus; protein complex assembly; regulation of exit from mitosis; spindle pole,PF10493;,5.00E-16,CHOYP_KNTC1.1.1,,,,,,,KNTC1_HUMAN,Homo sapiens (Human),cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062] comp91745_c2_seq1,301,44.186,0.41655632,6,0,,5.00E-47,Q8NFA0,Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),GO:0005794; GO:0005509; GO:0008234; GO:0016020; GO:0016579; GO:0004221; GO:0006511,Golgi apparatus; calcium ion binding; cysteine-type peptidase activity; membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF06337;PF13202;PF14836;PF00443;,9.00E-49,CHOYP_UBP32.1.1,,,,,,,UBP32_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp91749_c0_seq1,233,45.9227,0.57353998,0,13,,,,,,,,,5.00E-12,CHOYP_LOC100709254.1.1,,,,,,,,, comp91777_c3_seq1,206,43.2039,0.43810556,2,9,,2.00E-09,Q8L7W2,Nudix hydrolase 8 (AtNUDT8) (EC 3.6.1.-),Nudix hydrolase 8 (AtNUDT8) (EC 3.6.1.-),GO:0016787; GO:0046872; GO:0009611,hydrolase activity; metal ion binding; response to wounding,PF00293;,,,,,,,,,NUDT8_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to wounding [GO:0009611] comp91786_c0_seq1,556,36.3309,0.61239578,6,25,,2.00E-06,Q15399,Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281),Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281),GO:0002755; GO:0042088; GO:0035354; GO:0071727; GO:0042496; GO:0042495; GO:0006955; GO:0006954; GO:0045087; GO:0005887; GO:0042116; GO:0030670; GO:0045410; GO:0042535; GO:0046982; GO:0050707; GO:0034150; GO:0004888,MyD88-dependent toll-like receptor signaling pathway; T-helper 1 type immune response; Toll-like receptor 1-Toll-like receptor 2 protein complex; cellular response to triacyl bacterial lipopeptide; detection of diacyl bacterial lipopeptide; detection of triacyl bacterial lipopeptide; immune response; inflammatory response; innate immune response; integral to plasma membrane; macrophage activation; phagocytic vesicle membrane; positive regulation of interleukin-6 biosynthetic process; positive regulation of tumor necrosis factor biosynthetic process; protein heterodimerization activity; regulation of cytokine secretion; toll-like receptor 6 signaling pathway; transmembrane signaling receptor activity,PF13855;PF01463;PF01582;,,,,,,,,,TLR1_HUMAN,Homo sapiens (Human),cellular response to triacyl bacterial lipopeptide [GO:0071727]; defense response to bacterium [GO:0042742]; detection of triacyl bacterial lipopeptide [GO:0042495]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation [GO:0042116]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of cytokine secretion [GO:0050707]; signal transduction [GO:0007165]; toll-like receptor 1 signaling pathway [GO:0034130]; toll-like receptor signaling pathway [GO:0002224]; toll-like receptor TLR1:TLR2 signaling pathway [GO:0038123] comp91803_c0_seq2,224,46.875,0.73530877,0,6,,7.00E-18,Q0CDB3,Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),GO:0004177; GO:0009987; GO:0046872; GO:0008237; GO:0006508,aminopeptidase activity; cellular process; metal ion binding; metallopeptidase activity; proteolysis,PF01321;PF00557;PF16188;,,,,,,,,,AMPP1_ASPTN,Aspergillus terreus (strain NIH 2624 / FGSC A1156), comp91803_c1_seq1,235,44.6809,0.86695447,0,13,,1.00E-08,E3QCU0,Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase),GO:0004177; GO:0009987; GO:0046872; GO:0008237; GO:0006508,aminopeptidase activity; cellular process; metal ion binding; metallopeptidase activity; proteolysis,PF01321;PF00557;PF16188;,,,,,,,,,AMPP1_COLGM,Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola),negative regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034396] comp91805_c0_seq1,571,45.359,0.44489786,4,56,,1.00E-35,Q60HF3,Hermansky-Pudlak syndrome 1 protein homolog,Hermansky-Pudlak syndrome 1 protein homolog,,,,,,,,,,,,HPS1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp91807_c1_seq1,424,44.1038,0.92497651,10,14,,1.00E-41,P41233,ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1),GO:0005524; GO:0006200; GO:0016887; GO:0007186; GO:0005794; GO:0008509; GO:0034188; GO:0071222; GO:0071300; GO:0033344; GO:0042632; GO:0008203; GO:0017127; GO:0016197; GO:0034380; GO:0005887; GO:0050702; GO:0032367; GO:0007040; GO:0045121; GO:0002790; GO:0045335; GO:0006911; GO:0033700; GO:0055091; GO:0045332; GO:0005548; GO:0060155; GO:0030819; GO:0010875; GO:0006497; GO:0032489; GO:0034616; GO:0055098; GO:0043691,"ATP binding; ATP catabolic process; ATPase activity; G-protein coupled receptor signaling pathway; Golgi apparatus; anion transmembrane transporter activity; apolipoprotein A-I receptor activity; cellular response to lipopolysaccharide; cellular response to retinoic acid; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transporter activity; endosomal transport; high-density lipoprotein particle assembly; integral to plasma membrane; interleukin-1 beta secretion; intracellular cholesterol transport; lysosome organization; membrane raft; peptide secretion; phagocytic vesicle; phagocytosis, engulfment; phospholipid efflux; phospholipid homeostasis; phospholipid translocation; phospholipid transporter activity; platelet dense granule organization; positive regulation of cAMP biosynthetic process; positive regulation of cholesterol efflux; protein lipidation; regulation of Cdc42 protein signal transduction; response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; reverse cholesterol transport",PF00005;,2.00E-51,CHOYP_ABCA1.3.3,,,,,,,ABCA1_MOUSE,Mus musculus (Mouse),"cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]" comp91813_c0_seq1,482,38.5892,0.51793384,12,20,,1.00E-32,A6QR44,Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog),Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog),GO:0005737; GO:0003725; GO:0046872; GO:0015630; GO:0005730; GO:0031053,cytoplasm; double-stranded RNA binding; metal ion binding; microtubule cytoskeleton; nucleolus; primary miRNA processing,PF00035;,,,,,,,,,DGCR8_BOVIN,Bos taurus (Bovine),primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091] comp91834_c0_seq1,416,57.9327,1.22647768,2,35,,4.00E-19,Q9KBQ3,Ribulokinase (EC 2.7.1.16),Ribulokinase (EC 2.7.1.16),GO:0005524; GO:0019569; GO:0008741,ATP binding; L-arabinose catabolic process to xylulose 5-phosphate; ribulokinase activity,PF02782;PF00370;,,,,,,,,,ARAB_BACHD,Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125),L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569] comp9183_c0_seq1,356,40.1685,0.28044212,5,0,,2.00E-47,Q9Y3Z3,Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1),Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1),GO:0003723; GO:0051607; GO:0006955; GO:0045087; GO:0008152; GO:0046872; GO:0005634; GO:0008081; GO:0045088,RNA binding; defense response to virus; immune response; innate immune response; metabolic process; metal ion binding; nucleus; phosphoric diester hydrolase activity; regulation of innate immune response,PF01966;PF07647;,7.00E-32,CHOYP_SAMH1.12.12,,,,,,,SAMH1_HUMAN,Homo sapiens (Human),dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; immune response [GO:0006955]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; type I interferon signaling pathway [GO:0060337] comp91842_c0_seq1,691,37.3372,0.54062613,13,4,,1.00E-29,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,5.00E-18,CHOYP_LOC754648.1.3,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp91851_c1_seq1,937,41.9424,0.50525239,24,215,,6.00E-89,Q62415,Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B),Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B),GO:0005737; GO:0072332; GO:0045786; GO:0005634; GO:0005886,cytoplasm; intrinsic apoptotic signaling pathway by p53 class mediator; negative regulation of cell cycle; nucleus; plasma membrane,PF12796;PF00018;,4.00E-103,CHOYP_LOC100646232.1.1,,,,,,,ASPP1_MOUSE,Mus musculus (Mouse),intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell cycle [GO:0045786] comp91869_c0_seq1,874,47.5973,0.44759173,28,30,,6.00E-28,O14686,Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.43) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2),Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.43) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2),GO:0006342; GO:0051568; GO:0035097; GO:0018024; GO:0001701; GO:0001555; GO:0008284; GO:0033148; GO:0045944; GO:0043627; GO:0044212; GO:0006351; GO:0008270,"chromatin silencing; histone H3-K4 methylation; histone methyltransferase complex; histone-lysine N-methyltransferase activity; in utero embryonic development; oocyte growth; positive regulation of cell proliferation; positive regulation of intracellular estrogen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; response to estrogen stimulus; transcription regulatory region DNA binding; transcription, DNA-dependent; zinc ion binding",PF05965;PF05964;PF00628;PF00856;,7.00E-18,CHOYP_MLL2.1.1,,,,,,,MLL2_HUMAN,Homo sapiens (Human),"beta-catenin-TCF complex assembly [GO:1904837]; chromatin silencing [GO:0006342]; histone H3-K4 methylation [GO:0051568]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]" comp91878_c0_seq1,329,43.1611,0.33266436,10,2,,2.00E-32,Q5R4F9,Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89),Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89),GO:0004091; GO:0051722; GO:0006482; GO:0051721,carboxylesterase activity; protein C-terminal methylesterase activity; protein demethylation; protein phosphatase 2A binding,PF12697;,5.00E-27,CHOYP_PPME1.1.1,,,,,,,PPME1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein demethylation [GO:0006482] comp91879_c0_seq1,2142,39.1223,1.03855957,4037,1,male>female,1.00E-08,Q6B9X6,Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase),GO:0005524; GO:0005516; GO:0031164; GO:0000331; GO:0005829; GO:0000281; GO:0031038; GO:0018209; GO:0018107; GO:0048471; GO:0004674; GO:0031156; GO:0031288,ATP binding; calmodulin binding; contractile vacuolar membrane; contractile vacuole; cytosol; mitotic cytokinesis; myosin II filament organization; peptidyl-serine modification; peptidyl-threonine phosphorylation; perinuclear region of cytoplasm; protein serine/threonine kinase activity; regulation of sorocarp development; sorocarp morphogenesis,PF02816;,,,,,,,,,VWKA_DICDI,Dictyostelium discoideum (Slime mold),contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288] comp91881_c0_seq1,961,49.0114,0.6851609,43,16,,6.00E-20,Q811L6,Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1),Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1),GO:0005524; GO:0005737; GO:0000287; GO:0004674,ATP binding; cytoplasm; magnesium ion binding; protein serine/threonine kinase activity,PF08926;PF00595;PF00069;,7.00E-18,CHOYP_MAST4.1.1,,,,,,,MAST4_MOUSE,Mus musculus (Mouse),intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] comp91892_c0_seq1,233,59.2275,1.1390686,0,4,,7.00E-08,P55679,Uncharacterized zinc protease y4wA (EC 3.4.24.-),Uncharacterized zinc protease y4wA (EC 3.4.24.-),GO:0016021; GO:0046872; GO:0004222; GO:0005886; GO:0006508,integral to membrane; metal ion binding; metalloendopeptidase activity; plasma membrane; proteolysis,PF00675;PF05193;,,,,,,,,,Y4WA_RHISN,Sinorhizobium fredii (strain NBRC 101917 / NGR234), comp91924_c1_seq1,360,45.8333,0.44431112,8,34,,2.00E-26,P31228,D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1),GO:0003884; GO:0008445; GO:0005777,D-amino-acid oxidase activity; D-aspartate oxidase activity; peroxisome,PF01266;,,,,,,,,,OXDD_BOVIN,Bos taurus (Bovine),D-amino acid metabolic process [GO:0046416] comp91925_c0_seq1,208,63.4615,1.34377388,0,6,,1.00E-18,P0C0X1,Dihydropteroate synthase 1 (DHPS 1) (EC 2.5.1.15) (Dihydropteroate pyrophosphorylase 1),Dihydropteroate synthase (DHPS) (EC 2.5.1.15) (Dihydropteroate pyrophosphorylase),GO:0004156; GO:0046656; GO:0046872; GO:0046677; GO:0046654,dihydropteroate synthase activity; folic acid biosynthetic process; metal ion binding; response to antibiotic; tetrahydrofolate biosynthetic process,PF00809;,,,,,,,,,DHPS1_MYCLE,Mycobacterium leprae (strain TN),folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654] comp91938_c0_seq2,405,45.679,0.67139554,3,22,,2.00E-07,P70475,Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1),Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1),GO:0001105; GO:0030154; GO:0007399; GO:0005634; GO:0044323; GO:0003700; GO:0008270,RNA polymerase II transcription coactivator activity; cell differentiation; nervous system development; nucleus; retinoic acid-responsive element binding; sequence-specific DNA binding transcription factor activity; zinc ion binding,PF08474;PF01530;,,,,,,,,,MYT1L_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp91965_c0_seq1,402,45.0249,0.78730646,9,12,,2.00E-17,Q5T619,Zinc finger protein 648,Zinc finger protein 648,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,7.00E-20,CHOYP_ZN181.1.1,,,,,,,ZN648_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp91968_c1_seq1,246,38.6179,0.34529928,1,0,,4.00E-29,Q8JZW4,Copine-5 (Copine V),Copine-5 (Copine V),GO:0043005; GO:0043025,neuron projection; neuronal cell body,PF00168;PF07002;,3.00E-35,CHOYP_LOC586076.1.1,6.00E-22,ruditapes_c6973,,,,,CPNE5_MOUSE,Mus musculus (Mouse),positive regulation of dendrite extension [GO:1903861] comp92001_c1_seq1,701,38.8017,0.73257687,29,10,,3.00E-15,Q9V4A7,Plexin-B,Plexin-B,GO:0016021; GO:0005622; GO:0008045; GO:0035021; GO:0005886; GO:0035025; GO:0004872; GO:0007165,integral to membrane; intracellular; motor neuron axon guidance; negative regulation of Rac protein signal transduction; plasma membrane; positive regulation of Rho protein signal transduction; receptor activity; signal transduction,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; negative regulation of Rac protein signal transduction [GO:0035021]; olfactory bulb axon guidance [GO:0071678]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374] comp92001_c2_seq1,275,45.0909,0.71819841,8,15,,2.00E-08,B2RXS4,Plexin-B2,Plexin-B2,GO:0007420; GO:0005887; GO:0005622; GO:0001843; GO:0007405; GO:0050772; GO:0032319; GO:0008360; GO:2001222; GO:0001932; GO:0017154,brain development; integral to plasma membrane; intracellular; neural tube closure; neuroblast proliferation; positive regulation of axonogenesis; regulation of Rho GTPase activity; regulation of cell shape; regulation of neuron migration; regulation of protein phosphorylation; semaphorin receptor activity,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXB2_MOUSE,Mus musculus (Mouse),brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] comp92018_c1_seq1,371,42.3181,0.78507064,7,27,,5.00E-12,Q16587,Zinc finger protein 74 (Zinc finger protein 520) (hZNF7),Zinc finger protein 74 (Zinc finger protein 520) (hZNF7),GO:0003677; GO:0003723; GO:0015629; GO:0046872; GO:0007275; GO:0005634; GO:0006355; GO:0006351,"DNA binding; RNA binding; actin cytoskeleton; metal ion binding; multicellular organismal development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZNF74_HUMAN,Homo sapiens (Human),"multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp92023_c1_seq1,645,40.9302,0.66751022,34,0,,5.00E-16,Q86WI1,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1),GO:0005829; GO:0005615; GO:0006955; GO:0016021; GO:0004872,cytosol; extracellular space; immune response; integral to membrane; receptor activity,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_HUMAN,Homo sapiens (Human),immune response [GO:0006955] comp92061_c0_seq1,518,39.9614,0.59655395,18,0,,1.00E-18,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp92070_c0_seq1,222,38.2883,0.74087882,2,23,,8.00E-27,O35156,UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase),GO:0003983; GO:0005737; GO:0046872,UTP:glucose-1-phosphate uridylyltransferase activity; cytoplasm; metal ion binding,PF01704;,3.00E-28,CHOYP_UGPA.1.1,,,,,,,UGPA_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),UDP-glucose metabolic process [GO:0006011] comp92093_c0_seq1,452,42.4779,0.84887982,8,24,,7.00E-25,Q8HXG8,"Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)","Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)",GO:0016119; GO:0046872; GO:0005739; GO:0016702,"carotene metabolic process; metal ion binding; mitochondrion; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen",PF03055;,,,,,,,,,BCDO2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),carotene metabolic process [GO:0016119] comp92095_c0_seq1,334,38.024,0.33483559,19,0,,3.00E-08,P51798,H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7),GO:0005524; GO:0015297; GO:0005254; GO:0031410; GO:0016021; GO:0005765; GO:0009268; GO:0005247,ATP binding; antiporter activity; chloride channel activity; cytoplasmic vesicle; integral to membrane; lysosomal membrane; response to pH; voltage-gated chloride channel activity,PF00571;PF00654;,,,,,,,,,CLCN7_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810] comp92102_c0_seq1,414,47.343,0.45772326,92,625,,2.00E-06,Q5NVE2,Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein),Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein),GO:0048471; GO:0006355; GO:0006351,"perinuclear region of cytoplasm; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09073;,,,,,,,,,SRFB1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp92107_c0_seq1,581,44.7504,0.76128414,13,17,,3.00E-52,Q7Z5R6,Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Rap1-GTP-interacting adapter molecule) (RIAM) (Retinoic acid-responsive proline-rich protein 1) (RARP-1),Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Rap1-GTP-interacting adapter molecule) (RIAM) (Retinoic acid-responsive proline-rich protein 1) (RARP-1),GO:0005856; GO:0005829; GO:0005925; GO:0030027; GO:0005543; GO:0005886; GO:0030168; GO:0007165,cytoskeleton; cytosol; focal adhesion; lamellipodium; phospholipid binding; plasma membrane; platelet activation; signal transduction,PF00169;PF00788;,1.00E-63,CHOYP_ISCW_ISCW014636.2.2,,,,,,,AB1IP_HUMAN,Homo sapiens (Human),positive regulation of cell adhesion [GO:0045785]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] comp92125_c0_seq1,335,48.6567,0.87742717,6,13,,2.00E-40,Q5ZI58,Protein FAM214A,Protein FAM214A,,,PF13889;PF13915;,2.00E-38,CHOYP_FAM214A.1.1,,,,,,,F214A_CHICK,Gallus gallus (Chicken), comp92129_c0_seq1,255,36.0784,0.37427476,7,0,,1.00E-18,Q9P2C4,Transmembrane protein 181,Transmembrane protein 181,GO:0016021; GO:0009405; GO:0015643,integral to membrane; pathogenesis; toxic substance binding,,2.00E-17,CHOYP_CPIPJ_CPIJ015767.1.1,,,,,,,TM181_HUMAN,Homo sapiens (Human),pathogenesis [GO:0009405] comp92141_c0_seq1,380,45.5263,0.71348809,9,12,,1.00E-09,Q8NFW9,Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c),Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c),GO:0015629; GO:0031045; GO:0000145; GO:0006886; GO:0042470; GO:0048471; GO:0001750; GO:0032024; GO:0045202; GO:0030133; GO:0008270,actin cytoskeleton; dense core granule; exocyst; intracellular protein transport; melanosome; perinuclear region of cytoplasm; photoreceptor outer segment; positive regulation of insulin secretion; synapse; transport vesicle; zinc ion binding,PF02318;PF04698;,,,,,,,,,MYRIP_HUMAN,Homo sapiens (Human),intracellular protein transport [GO:0006886]; positive regulation of insulin secretion [GO:0032024] comp92145_c0_seq1,225,52.8889,1.4165522,0,9,,1.00E-15,P65052,Uncharacterized protein Mb2925c,Uncharacterized protein Mb2925c,,,PF10611;,,,,,,,,,Y2925_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97), comp92146_c1_seq1,694,39.049,0.6814482,24,5,,4.00E-38,Q7LHG5,Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)],GO:0005524; GO:0003677; GO:0015074; GO:0006310; GO:0003887; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0005737; GO:0008233; GO:0006508; GO:0000943; GO:0004523; GO:0004540; GO:0032197; GO:0046797; GO:0008270,"ATP binding; DNA binding; DNA integration; DNA recombination; DNA-directed DNA polymerase activity; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; cytoplasm; peptidase activity; proteolysis; retrotransposon nucleocapsid; ribonuclease H activity; ribonuclease activity; transposition, RNA-mediated; viral procapsid maturation; zinc ion binding",PF12384;PF00665;PF00078;,9.00E-53,CHOYP_LOC100708199.3.6,,,,,,,YI31B_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]" comp92152_c0_seq1,282,41.1348,0.17866386,1,0,,3.00E-15,Q4V7Q6,Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3),Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3),GO:0005524; GO:0006914; GO:0005737; GO:0045879; GO:0045880; GO:0046777; GO:0004674,ATP binding; autophagy; cytoplasm; negative regulation of smoothened signaling pathway; positive regulation of smoothened signaling pathway; protein autophosphorylation; protein serine/threonine kinase activity,PF04212;PF00069;,2.00E-12,CHOYP_BRAFLDRAFT_110776.1.1,,,,,,,ULK3_XENLA,Xenopus laevis (African clawed frog),autophagy [GO:0006914]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777] comp92160_c0_seq1,226,42.9204,0.67618345,7,0,,9.00E-06,E1CHH8,Vertnin,Vertnin,GO:0043565,sequence-specific DNA binding,,,,,,,,,,VRTN_PIG,Sus scrofa (Pig), comp92161_c0_seq1,781,38.2843,0.45710507,19,47,,4.00E-13,F1MBP6,Kelch-like protein 3,Kelch-like protein 3,GO:0031463; GO:0005856; GO:0005829; GO:0072156; GO:0050801; GO:0070936; GO:0042787; GO:0070294,Cul3-RING ubiquitin ligase complex; cytoskeleton; cytosol; distal tubule morphogenesis; ion homeostasis; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; renal sodium ion absorption,PF07707;PF00651;PF01344;,1.00E-51,CHOYP_ISCW_ISCW016591.1.1,,,,,,,KLHL3_BOVIN,Bos taurus (Bovine),distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294] comp92163_c0_seq1,469,48.8273,0.39769412,0,0,,2.00E-18,Q9FHN8,Kinesin-like calmodulin-binding protein (Protein ZWICHEL),Kinesin-like calmodulin-binding protein (Protein ZWICHEL),GO:0043531; GO:0005524; GO:0016887; GO:0005509; GO:0005516; GO:0005871; GO:0008017; GO:0003777; GO:0007018; GO:0016491; GO:0010091,ADP binding; ATP binding; ATPase activity; calcium ion binding; calmodulin binding; kinesin complex; microtubule binding; microtubule motor activity; microtubule-based movement; oxidoreductase activity; trichome branching,PF00373;PF09379;PF00225;PF00784;,,,,,,,,,KCBP_ARATH,Arabidopsis thaliana (Mouse-ear cress),microtubule-based movement [GO:0007018]; trichome branching [GO:0010091] comp92163_c0_seq2,519,48.1696,0.33539856,3,0,,7.00E-31,P23678,Kinesin-like protein unc-104 (Uncoordinated protein 104),Kinesin-like protein unc-104 (Uncoordinated protein 104),GO:0005524; GO:0008089; GO:0030424; GO:0007049; GO:0051301; GO:0005737; GO:0030421; GO:0030425; GO:0007631; GO:0005871; GO:0005874; GO:0008017; GO:0018996; GO:0002119; GO:0007270; GO:0005546; GO:0070273; GO:0008574; GO:0040010; GO:0040018; GO:0010940; GO:0045887; GO:0043113; GO:0045055; GO:0030516; GO:0006942; GO:0000003; GO:0045202; GO:0007271,"ATP binding; anterograde axon cargo transport; axon; cell cycle; cell division; cytoplasm; defecation; dendrite; feeding behavior; kinesin complex; microtubule; microtubule binding; molting cycle, collagen and cuticulin-based cuticle; nematode larval development; neuron-neuron synaptic transmission; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; plus-end-directed microtubule motor activity; positive regulation of growth rate; positive regulation of multicellular organism growth; positive regulation of necrotic cell death; positive regulation of synaptic growth at neuromuscular junction; receptor clustering; regulated secretory pathway; regulation of axon extension; regulation of striated muscle contraction; reproduction; synapse; synaptic transmission, cholinergic",PF12473;PF12423;PF00225;PF16183;PF00169;,2.00E-14,CHOYP_LOC576465.1.1,,,,,,,UN104_CAEEL,Caenorhabditis elegans,"anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; cell cycle [GO:0007049]; cell division [GO:0051301]; defecation [GO:0030421]; feeding behavior [GO:0007631]; microtubule-based movement [GO:0007018]; molting cycle, collagen and cuticulin-based cuticle [GO:0018996]; negative regulation of dense core granule transport [GO:1904810]; nematode larval development [GO:0002119]; neuron-neuron synaptic transmission [GO:0007270]; neuron remodeling [GO:0016322]; positive regulation of growth rate [GO:0040010]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of pharyngeal pumping [GO:1903746]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; receptor clustering [GO:0043113]; regulated exocytosis [GO:0045055]; regulation of axon extension [GO:0030516]; regulation of protein localization to synapse [GO:1902473]; regulation of striated muscle contraction [GO:0006942]; reproduction [GO:0000003]; synaptic transmission, cholinergic [GO:0007271]; vesicle-mediated transport [GO:0016192]" comp92164_c0_seq1,225,44.8889,0.62040441,11,3,,3.00E-10,P74615,Uncharacterized protein sll1483,Uncharacterized protein sll1483,GO:0030288,outer membrane-bounded periplasmic space,PF02469;,,,,,,,,,Y1483_SYNY3,Synechocystis sp. (strain PCC 6803 / Kazusa), comp92171_c0_seq1,279,40.5018,0.79446166,6,0,,1.00E-08,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp92172_c1_seq1,369,41.4634,0.70635715,14,9,,,,,,,,,4.00E-22,CHOYP_LOC100185060.1.2,,,,,,,,, comp92178_c0_seq1,378,62.6984,1.08054926,3,12,,1.00E-31,B1MGY6,Uncharacterized tRNA/rRNA methyltransferase MAB_0572 (EC 2.1.1.-),Uncharacterized tRNA/rRNA methyltransferase MAB_0572 (EC 2.1.1.-),GO:0003723; GO:0001510; GO:0008173; GO:0006396,RNA binding; RNA methylation; RNA methyltransferase activity; RNA processing,PF00588;PF08032;,,,,,,,,,Y572_MYCA9,Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543),RNA processing [GO:0006396] comp92204_c0_seq1,913,42.9354,1.09729749,57,8,,2.00E-44,O75897,Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2),GO:0050427; GO:0005829; GO:0051923; GO:0008146; GO:0006805,3'-phosphoadenosine 5'-phosphosulfate metabolic process; cytosol; sulfation; sulfotransferase activity; xenobiotic metabolic process,PF00685;,,,,,,,,,ST1C4_HUMAN,Homo sapiens (Human),3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923] comp92223_c1_seq1,446,32.9596,0.4356747,0,7,,,,,,,,,1.00E-24,CHOYP_PHUM_PHUM267720.2.2,,,,,,,,, comp92223_c1_seq2,542,33.7638,0.54354539,7,26,,6.00E-27,Q61233,Plastin-2 (65 kDa macrophage protein) (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (pp65),Plastin-2 (65 kDa macrophage protein) (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (pp65),GO:0002286; GO:0005884; GO:0051015; GO:0051017; GO:0005509; GO:0030054; GO:0005829; GO:0001891; GO:0033157; GO:0001726; GO:0032587,T cell activation involved in immune response; actin filament; actin filament binding; actin filament bundle assembly; calcium ion binding; cell junction; cytosol; phagocytic cup; regulation of intracellular protein transport; ruffle; ruffle membrane,PF00307;PF13499;,1.00E-24,CHOYP_FIM.1.1,,,,,,,PLSL_MOUSE,Mus musculus (Mouse),actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; organ regeneration [GO:0031100]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; response to wounding [GO:0009611]; T cell activation involved in immune response [GO:0002286] comp92251_c0_seq2,491,43.1772,0.26275142,3,0,,5.00E-31,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,3.00E-38,CHOYP_UBR3.1.1,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp92260_c0_seq1,384,44.0104,0.48734508,16,0,,1.00E-32,P33173,Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles),Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles),GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0008017; GO:0003777; GO:0007018; GO:0043005; GO:0043025; GO:0005543,ATP binding; cytoplasm; kinesin complex; microtubule; microtubule binding; microtubule motor activity; microtubule-based movement; neuron projection; neuronal cell body; phospholipid binding,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,,,,,,,,,KIF1A_MOUSE,Mus musculus (Mouse),cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018] comp92267_c0_seq1,352,65.9091,1.1031339,0,20,,5.00E-27,A4WNM9,(3S)-malyl-CoA thioesterase (EC 3.1.2.n2) ((3S)-malyl-CoA thiolesterase),(3S)-malyl-CoA thioesterase (EC 3.1.2.30) ((3S)-malyl-CoA thiolesterase),GO:0006725; GO:0008815; GO:0009346; GO:0046872; GO:0016790,cellular aromatic compound metabolic process; citrate (pro-3S)-lyase activity; citrate lyase complex; metal ion binding; thiolester hydrolase activity,PF03328;,,,,,,,,,MCTE_RHOS5,Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3), comp92270_c0_seq1,408,49.7549,0.35835496,10,12,,2.00E-49,O75417,DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta),GO:0005524; GO:0008026; GO:0006281; GO:0006260; GO:0003887; GO:0003684; GO:0005654; GO:0043142,ATP binding; ATP-dependent helicase activity; DNA repair; DNA replication; DNA-directed DNA polymerase activity; damaged DNA binding; nucleoplasm; single-stranded DNA-dependent ATPase activity,PF00270;PF00476;PF00271;,1.00E-42,CHOYP_BRAFLDRAFT_251779.2.2,,,,,,,DPOLQ_HUMAN,Homo sapiens (Human),base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] comp92272_c0_seq2,551,43.9201,0.49013207,13,40,,7.00E-72,Q5XXA6,Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2),Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2),GO:0034707; GO:0005737; GO:0005229; GO:0007275; GO:0005886; GO:0042391,chloride channel complex; cytoplasm; intracellular calcium activated chloride channel activity; multicellular organismal development; plasma membrane; regulation of membrane potential,PF16178;PF04547;,9.00E-52,CHOYP_AAEL_AAEL006656.1.1,,,,,,,ANO1_HUMAN,Homo sapiens (Human),cation transport [GO:0006812]; cellular response to heat [GO:0034605]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; iodide transport [GO:0015705]; ion transmembrane transport [GO:0034220]; multicellular organism development [GO:0007275]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] comp92303_c0_seq1,239,56.9038,1.1421355,0,13,,3.00E-49,Q6ABL2,DNA replication and repair protein RecF,DNA replication and repair protein RecF,GO:0005524; GO:0006281; GO:0006260; GO:0009432; GO:0005737; GO:0003697,ATP binding; DNA repair; DNA replication; SOS response; cytoplasm; single-stranded DNA binding,PF02463;,,,,,,,,,RECF_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] comp92317_c0_seq1,318,42.7673,0.34501747,10,13,,1.00E-31,Q8R5L3,Vam6/Vps39-like protein,Vam6/Vps39-like protein,GO:0006886; GO:0031902; GO:0005765; GO:0005083; GO:0016192,intracellular protein transport; late endosome membrane; lysosomal membrane; small GTPase regulator activity; vesicle-mediated transport,PF00637;PF00780;PF10366;PF10367;,4.00E-22,CHOYP_LOC100378848.1.1,,,,,,,VPS39_MOUSE,Mus musculus (Mouse),"autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]; vesicle-mediated transport [GO:0016192]" comp92335_c0_seq2,538,39.9628,0.374112,9,0,,4.00E-16,Q91V93,Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein homolog),Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein homolog),GO:0005525; GO:0005622; GO:0007264,GTP binding; intracellular; small GTPase mediated signal transduction,PF00651;PF00071;,,,,,,,,,RHBT2_MOUSE,Mus musculus (Mouse),small GTPase mediated signal transduction [GO:0007264] comp92341_c0_seq1,379,47.2296,1.09114368,3,25,,2.00E-39,P97872,Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5),GO:0004499; GO:0050661; GO:0005789; GO:0050660; GO:0016021,"N,N-dimethylaniline monooxygenase activity; NADP binding; endoplasmic reticulum membrane; flavin adenine dinucleotide binding; integral to membrane",PF00743;,,,,,,,,,FMO5_MOUSE,Mus musculus (Mouse),drug metabolic process [GO:0017144] comp92374_c0_seq1,389,35.7326,0.43103733,19,6,,4.00E-08,Q9ESK9,RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180),RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180),GO:0007254; GO:0070969; GO:0000045; GO:0007049; GO:0005829; GO:0007507; GO:0001889; GO:0043066; GO:2001237; GO:0005634; GO:0045793; GO:0001934; GO:0034045; GO:0010506; GO:0006355; GO:0006351,"JNK cascade; ULK1-ATG13-FIP200 complex; autophagic vacuole assembly; cell cycle; cytosol; heart development; liver development; negative regulation of apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; nucleus; positive regulation of cell size; positive regulation of protein phosphorylation; pre-autophagosomal structure membrane; regulation of autophagy; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF10377;,2.00E-14,CHOYP_RBCC1.2.2,,,,,,,RBCC1_MOUSE,Mus musculus (Mouse),"autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell cycle [GO:0007049]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell size [GO:0045793]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp92382_c0_seq1,265,51.3208,0.57839484,5,5,,,,,,,,,5.00E-13,CHOYP_BRAFLDRAFT_117157.1.3,,,,,,,,, comp92385_c0_seq2,1112,46.1331,0.18610358,35,24,,2.00E-144,Q8NFP9,Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B),Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B),GO:0005829; GO:0012505; GO:0005886; GO:0008104; GO:0005802,cytosol; endomembrane system; plasma membrane; protein localization; trans-Golgi network,PF02138;PF06469;PF15787;PF14844;,2.00E-165,CHOYP_LOC100646535.1.1,,,,,,,NBEA_HUMAN,Homo sapiens (Human),protein localization [GO:0008104] comp92390_c0_seq1,404,43.0693,0.32258262,11,2,,1.00E-62,Q9BZC7,ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2),GO:0005524; GO:0043190; GO:0042626; GO:0042632; GO:0016023; GO:0005768; GO:0010008; GO:0016021; GO:0006629; GO:0005765; GO:0005764; GO:0005815; GO:0032383; GO:0006357; GO:0042493; GO:0048545,"ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity, coupled to transmembrane movement of substances; cholesterol homeostasis; cytoplasmic membrane-bounded vesicle; endosome; endosome membrane; integral to membrane; lipid metabolic process; lysosomal membrane; lysosome; microtubule organizing center; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus",PF00005;,5.00E-22,CHOYP_ABCA1.1.3,,,,,,,ABCA2_HUMAN,Homo sapiens (Human),cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810] comp92404_c0_seq1,535,34.5794,0.43862674,14,13,,1.00E-30,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp92405_c0_seq1,369,44.4444,0.99285166,22,8,,2.00E-14,P15304,Hormone-sensitive lipase (HSL) (EC 3.1.1.79),Hormone-sensitive lipase (HSL) (EC 3.1.1.79),GO:0047372; GO:0005901; GO:0008203; GO:0005829; GO:0005615; GO:0007565; GO:0033878; GO:0005811; GO:0005739; GO:0005634; GO:0042134; GO:0042493; GO:0006363; GO:0006361; GO:0019433,acylglycerol lipase activity; caveola; cholesterol metabolic process; cytosol; extracellular space; female pregnancy; hormone-sensitive lipase activity; lipid particle; mitochondrion; nucleus; rRNA primary transcript binding; response to drug; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; triglyceride catabolic process,PF07859;PF06350;,,,,,,,,,LIPS_RAT,Rattus norvegicus (Rat),cholesterol metabolic process [GO:0008203]; female pregnancy [GO:0007565]; lipid catabolic process [GO:0016042]; response to drug [GO:0042493]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation from RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433] comp92415_c0_seq1,601,46.589,0.37790437,16,24,,3.00E-68,Q0WML0,ABC transporter B family member 27 (ABC transporter ABCB.27) (AtABCB27) (Aluminum tolerance-related ATP-binding cassette transporter) (Antigen peptide transporter-like 2) (Transporter associated with antigen processing-like protein 2) (AtTAP2),ABC transporter B family member 27 (ABC transporter ABCB.27) (AtABCB27) (Aluminum tolerance-related ATP-binding cassette transporter) (Antigen peptide transporter-like 2) (Transporter associated with antigen processing-like protein 2) (AtTAP2),GO:0005524; GO:0016021; GO:0015421; GO:0000325; GO:0005886; GO:0010044; GO:0005774,ATP binding; integral to membrane; oligopeptide-transporting ATPase activity; plant-type vacuole; plasma membrane; response to aluminum ion; vacuolar membrane,PF00664;PF00005;,2.00E-93,CHOYP_BRAFLDRAFT_84327.1.2,,,,,,,AB27B_ARATH,Arabidopsis thaliana (Mouse-ear cress),response to aluminum ion [GO:0010044]; transmembrane transport [GO:0055085] comp92421_c0_seq1,256,64.8438,0.93483167,0,27,,5.00E-11,P0AAR4,Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK (EC 4.2.-.-),Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK (EC 4.2.-.-),GO:0002161; GO:0005737; GO:0016829; GO:0006450; GO:0006412,aminoacyl-tRNA editing activity; cytoplasm; lyase activity; regulation of translational fidelity; translation,PF04073;,,,,,,,,,YBAK_SHIFL,Shigella flexneri,translation [GO:0006412] comp92422_c0_seq2,561,47.0588,0.90645449,8,29,,1.00E-32,Q09128,"1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.13.126) (Cytochrome P450 24A1) (Cytochrome P450-CC24)","1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24)",GO:0030342; GO:0008403; GO:0020037; GO:0005506; GO:0005739; GO:0001649; GO:0033280; GO:0042369,"1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; 25-hydroxycholecalciferol-24-hydroxylase activity; heme binding; iron ion binding; mitochondrion; osteoblast differentiation; response to vitamin D; vitamin D catabolic process",PF00067;,,,,,,,,,CP24A_RAT,Rattus norvegicus (Rat),osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359] comp92423_c1_seq2,282,41.1348,0.4712014,0,0,,,,,,,,,,,4.00E-12,ruditapes2_c2420,,,,,,, comp92432_c0_seq1,220,46.8182,0.67430836,0,7,,1.00E-12,Q09225,Nose resistant to fluoxetine protein 6 (Protein nrf-6),Nose resistant to fluoxetine protein 6 (Protein nrf-6),GO:0016021; GO:0008289; GO:0006869; GO:0007275; GO:0016747,"integral to membrane; lipid binding; lipid transport; multicellular organismal development; transferase activity, transferring acyl groups other than amino-acyl groups",PF01757;,,,,,,,,,NRF6_CAEEL,Caenorhabditis elegans,lipid transport [GO:0006869]; multicellular organism development [GO:0007275] comp92445_c0_seq1,243,41.5638,0.21747249,2,0,,8.00E-10,Q5XIS7,Ubiquitin-associated protein 1 (UBAP-1),Ubiquitin-associated protein 1 (UBAP-1),GO:0000813; GO:0005829; GO:0015031; GO:0043130; GO:0043162,ESCRT I complex; cytosol; protein transport; ubiquitin binding; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,,,,,,,,,,UBAP1_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] comp92460_c0_seq1,315,43.1746,0.69850394,10,9,,3.00E-08,P08478,Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)],Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)],GO:0005507; GO:0016021; GO:0006518; GO:0004598; GO:0004504; GO:0030658,copper ion binding; integral to membrane; peptide metabolic process; peptidylamidoglycolate lyase activity; peptidylglycine monooxygenase activity; transport vesicle membrane,PF03712;PF01082;PF01436;,,,,,,,,,AMDA_XENLA,Xenopus laevis (African clawed frog),peptide metabolic process [GO:0006518] comp92464_c1_seq1,393,47.5827,1.0906645,6,0,,2.00E-39,P10079,Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1),GO:0032579; GO:0005509; GO:0016023; GO:0005615,apical lamina of hyaline layer; calcium ion binding; cytoplasmic membrane-bounded vesicle; extracellular space,PF01382;PF00431;PF00008;,8.00E-19,CHOYP_LOC575161.3.5,,,,,,,FBP1_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp92468_c1_seq1,846,40.6619,0.34450782,41,4,,6.00E-16,Q8R0J4,Transmembrane protein 134,Transmembrane protein 134,GO:0016021,integral to membrane,PF05915;,,,,,,,,,TM134_MOUSE,Mus musculus (Mouse), comp92470_c0_seq1,319,43.8871,0.39256162,4,16,,2.00E-28,A4FV48,Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase),GO:0005789; GO:0020037; GO:0016021; GO:0005506; GO:0004768; GO:0006636,endoplasmic reticulum membrane; heme binding; integral to membrane; iron ion binding; stearoyl-CoA 9-desaturase activity; unsaturated fatty acid biosynthetic process,PF00173;PF00487;,5.00E-20,CHOYP_FADS2.1.2,,,,,,,FADS2_BOVIN,Bos taurus (Bovine),unsaturated fatty acid biosynthetic process [GO:0006636] comp92483_c0_seq1,541,32.5323,1.12917052,5,57,,2.00E-08,Q95SX7,Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase),GO:0003723; GO:0006278; GO:0003964; GO:0006313,"RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; transposition, DNA-mediated",PF14529;PF00078;,1.00E-12,CHOYP_LOC100561123.28.28,,,,,,,RTBS_DROME,Drosophila melanogaster (Fruit fly),"transposition, DNA-mediated [GO:0006313]" comp92485_c0_seq1,239,43.9331,0.75413732,10,6,,7.00E-12,Q05096,Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1),Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1),GO:0005524; GO:0003779; GO:0051017; GO:0030048; GO:0030898; GO:0005903; GO:0005516; GO:0005737; GO:0005856; GO:0030175; GO:0000146; GO:0016459; GO:0007399; GO:0005547; GO:0005546; GO:0005886,"ATP binding; actin binding; actin filament bundle assembly; actin filament-based movement; actin-dependent ATPase activity; brush border; calmodulin binding; cytoplasm; cytoskeleton; filopodium; microfilament motor activity; myosin complex; nervous system development; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane",PF00612;PF00063;PF06017;,,,,,,,,,MYO1B_RAT,Rattus norvegicus (Rat),actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892] comp92490_c0_seq1,281,43.0605,1.26119665,5,13,,7.00E-17,P18173,"Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]","Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]",GO:0006066; GO:0008812; GO:0005576; GO:0050660; GO:0004344; GO:0006006; GO:0008364; GO:0046693,alcohol metabolic process; choline dehydrogenase activity; extracellular region; flavin adenine dinucleotide binding; glucose dehydrogenase activity; glucose metabolic process; pupal chitin-based cuticle development; sperm storage,PF05199;PF00732;,,,,,,,,,DHGL_DROME,Drosophila melanogaster (Fruit fly),cuticle development [GO:0042335]; glucose metabolic process [GO:0006006]; pupal chitin-based cuticle development [GO:0008364]; sensory perception of pain [GO:0019233]; sperm storage [GO:0046693] comp92491_c0_seq1,310,49.3548,0.43045431,19,0,,7.00E-07,Q8NF91,Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1),GO:0005794; GO:0007030; GO:0034993; GO:0003779; GO:0008219; GO:0090286; GO:0005856; GO:0016021; GO:0042692; GO:0090292; GO:0031965; GO:0005640; GO:0045211; GO:0042803; GO:0030017,Golgi apparatus; Golgi organization; SUN-KASH complex; actin binding; cell death; cytoskeletal anchoring at nuclear membrane; cytoskeleton; integral to membrane; muscle cell differentiation; nuclear matrix anchoring at nuclear membrane; nuclear membrane; nuclear outer membrane; postsynaptic membrane; protein homodimerization activity; sarcomere,PF00307;PF10541;PF00435;,,,,,,,,,SYNE1_HUMAN,Homo sapiens (Human),cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997] comp92496_c1_seq1,251,41.0359,0.43637056,8,0,,2.00E-13,A4QN56,Sodium-dependent glucose transporter 1,Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B),GO:0016324; GO:0008643; GO:0016021; GO:0006814; GO:0015293,apical plasma membrane; carbohydrate transport; integral to membrane; sodium ion transport; symporter activity,PF07690;,,,,,,,,,NAGT1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] comp92498_c0_seq1,734,43.5967,0.37325746,26,11,,4.00E-12,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp92502_c0_seq1,389,48.329,1.0799656,14,7,,6.00E-10,P91682,Protein smoothened (SMOH) (Smooth) (dSMO),Protein smoothened (SMOH) (Smooth) (dSMO),GO:0001746; GO:0004930; GO:0030165; GO:0042813; GO:0017147; GO:0007193; GO:0048099; GO:0048846; GO:0007350; GO:0060070; GO:0010002; GO:0021696; GO:0060830; GO:0005929; GO:0007368; GO:0005768; GO:0007455; GO:0008406; GO:0003007; GO:0008158; GO:0005887; GO:2000134; GO:0045746; GO:0043066; GO:0048663; GO:0031102; GO:0043025; GO:0030707; GO:0090004; GO:0002052; GO:0045880; GO:0021938; GO:0035019; GO:0001570; GO:0048100,"Bolwig's organ morphogenesis; G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; anterior/posterior lineage restriction, imaginal disc; axon extension involved in axon guidance; blastoderm segmentation; canonical Wnt receptor signaling pathway; cardioblast differentiation; cerebellar cortex morphogenesis; ciliary receptor clustering involved in smoothened signaling pathway; cilium; determination of left/right symmetry; endosome; eye-antennal disc morphogenesis; gonad development; heart morphogenesis; hedgehog receptor activity; integral to plasma membrane; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of Notch signaling pathway; negative regulation of apoptotic process; neuron fate commitment; neuron projection regeneration; neuronal cell body; ovarian follicle cell development; positive regulation of establishment of protein localization to plasma membrane; positive regulation of neuroblast proliferation; positive regulation of smoothened signaling pathway; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; somatic stem cell maintenance; vasculogenesis; wing disc anterior/posterior pattern formation",PF01534;PF01392;,,,,,,,,,SMO_DROME,Drosophila melanogaster (Fruit fly),"adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; anterior/posterior lineage restriction, imaginal disc [GO:0048099]; blastoderm segmentation [GO:0007350]; Bolwig's organ morphogenesis [GO:0001746]; eye-antennal disc morphogenesis [GO:0007455]; eye morphogenesis [GO:0048592]; mucosal immune response [GO:0002385]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle cell development [GO:0030707]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; regulation of apoptotic process [GO:0042981]; regulation of mitotic cell cycle [GO:0007346]; signal transduction [GO:0007165]; smoothened signaling pathway [GO:0007224]; somatic stem cell population maintenance [GO:0035019]; wing disc anterior/posterior pattern formation [GO:0048100]" comp92527_c0_seq1,413,44.5521,0.88894712,17,14,,7.00E-22,Q91145,Collagen alpha-1(XII) chain (Fragment),Collagen alpha-1(XII) chain (Fragment),GO:0007155; GO:0005581,cell adhesion; collagen,PF00041;PF00092;,4.00E-16,CHOYP_LOC100538183.2.2,,,,,,,COCA1_NOTVI,Notophthalmus viridescens (Eastern newt) (Triturus viridescens),cell adhesion [GO:0007155] comp92552_c0_seq1,1111,42.8443,0.96577472,182,1478,,8.00E-100,Q2HJF4,Phenazine biosynthesis-like domain-containing protein (EC 5.1.-.-),Phenazine biosynthesis-like domain-containing protein (EC 5.1.-.-),GO:0009058; GO:0016853,biosynthetic process; isomerase activity,PF02567;,,,,,,,,,PBLD_BOVIN,Bos taurus (Bovine),biosynthetic process [GO:0009058]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein import into nucleus [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] comp92561_c0_seq1,208,67.3077,1.11104592,0,5,,9.00E-17,Q8XU39,Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase),Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase),GO:0006559; GO:0005506; GO:0004505,L-phenylalanine catabolic process; iron ion binding; phenylalanine 4-monooxygenase activity,PF00351;,,,,,,,,,PH4H_RALSO,Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum),L-phenylalanine catabolic process [GO:0006559] comp92571_c1_seq1,346,43.9306,0.49290184,8,19,,1.00E-36,Q60610,T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1),T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1),GO:0005089; GO:0031547; GO:0005911; GO:0048013; GO:0005085; GO:0005543; GO:0005886; GO:0050772; GO:0010976; GO:0005057; GO:0032314; GO:0007264,Rho guanyl-nucleotide exchange factor activity; brain-derived neurotrophic factor receptor signaling pathway; cell-cell junction; ephrin receptor signaling pathway; guanyl-nucleotide exchange factor activity; phospholipid binding; plasma membrane; positive regulation of axonogenesis; positive regulation of neuron projection development; receptor signaling protein activity; regulation of Rac GTPase activity; small GTPase mediated signal transduction,PF00595;PF00169;PF02196;PF00621;,8.00E-31,CHOYP_AGAP_AGAP006590.1.1,,,,,,,TIAM1_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; positive regulation of axonogenesis [GO:0050772]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; Rac protein signal transduction [GO:0016601]; regulation of dopaminergic neuron differentiation [GO:1904338]; regulation of GTPase activity [GO:0043087]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] comp92589_c1_seq1,229,36.2445,0.26744696,1,13,,,,,,,,,5.00E-12,CHOYP_contig_028648,,,,,,,,, comp92591_c0_seq1,227,40.5286,1.08212826,0,3,,6.00E-10,Q10743,Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) (Fragment),Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) (Fragment),GO:0005798; GO:0007219; GO:0009986; GO:0001701; GO:0016021; GO:0016020; GO:0006509; GO:0046872; GO:0004222; GO:0007162; GO:0005634; GO:0042803; GO:0019901; GO:0006468; GO:0045670; GO:0005802,Golgi-associated vesicle; Notch signaling pathway; cell surface; in utero embryonic development; integral to membrane; membrane; membrane protein ectodomain proteolysis; metal ion binding; metalloendopeptidase activity; negative regulation of cell adhesion; nucleus; protein homodimerization activity; protein kinase binding; protein phosphorylation; regulation of osteoclast differentiation; trans-Golgi network,PF00200;,,,,,,,,,ADA10_RAT,Rattus norvegicus (Rat),in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cell adhesion [GO:0007162]; Notch signaling pathway [GO:0007219]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670] comp92629_c1_seq1,355,41.1268,0.54685534,11,6,,3.00E-14,Q6ZNA5,Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2),GO:0000293; GO:0016021; GO:0046872,ferric-chelate reductase activity; integral to membrane; metal ion binding,PF03351;PF02014;,,,,,,,,,FRRS1_HUMAN,Homo sapiens (Human), comp92636_c0_seq1,204,46.0784,0.46740749,0,25,,3.00E-07,Q9SGZ5,Probable beta-D-xylosidase 7 (AtBXL7) (EC 3.2.1.-),Probable beta-D-xylosidase 7 (AtBXL7) (EC 3.2.1.-),GO:0048046; GO:0005975; GO:0009507; GO:0004553; GO:0009505; GO:0009506; GO:0005578,"apoplast; carbohydrate metabolic process; chloroplast; hydrolase activity, hydrolyzing O-glycosyl compounds; plant-type cell wall; plasmodesma; proteinaceous extracellular matrix",PF14310;PF00933;PF01915;,,,,,,,,,BXL7_ARATH,Arabidopsis thaliana (Mouse-ear cress),arabinan catabolic process [GO:0031222]; xylan catabolic process [GO:0045493] comp92657_c0_seq1,712,44.6629,0.48066875,38,0,,4.00E-19,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp92673_c1_seq1,266,48.1203,0.52780583,0,30,,2.00E-12,P80426,Serotransferrin-1 (Serotransferrin I) (STF I) (sTF1) (Siderophilin I),Serotransferrin-1 (Serotransferrin I) (STF I) (sTF1) (Siderophilin I),GO:0006879; GO:0005576; GO:0008199; GO:0006826,cellular iron ion homeostasis; extracellular region; ferric iron binding; iron ion transport,PF00405;,,,,,,,,,TRFE1_SALSA,Salmo salar (Atlantic salmon),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] comp92694_c0_seq1,343,45.481,0.56625996,7,0,,4.00E-41,Q9QYP1,Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7),GO:0016055; GO:0005509; GO:0030154; GO:0009953; GO:0042733; GO:0006897; GO:0001942; GO:0016021; GO:0001822; GO:0090090; GO:0030279; GO:0042475; GO:0005886; GO:0009954; GO:0043113; GO:0001932; GO:0051124,Wnt receptor signaling pathway; calcium ion binding; cell differentiation; dorsal/ventral pattern formation; embryonic digit morphogenesis; endocytosis; hair follicle development; integral to membrane; kidney development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of ossification; odontogenesis of dentin-containing tooth; plasma membrane; proximal/distal pattern formation; receptor clustering; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF12662;PF00057;PF00058;,,,,,,,,,LRP4_RAT,Rattus norvegicus (Rat),BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] comp92694_c0_seq2,327,44.0367,0.5698895,5,0,,3.00E-14,P01131,Low-density lipoprotein receptor (LDL receptor) (Fragment),Low-density lipoprotein receptor (LDL receptor) (Fragment),GO:0005794; GO:0009986; GO:0008203; GO:0005905; GO:0005769; GO:0006897; GO:0016021; GO:0005770; GO:0006869; GO:0034362; GO:0005764; GO:0005886,Golgi apparatus; cell surface; cholesterol metabolic process; coated pit; early endosome; endocytosis; integral to membrane; late endosome; lipid transport; low-density lipoprotein particle; lysosome; plasma membrane,PF00058;,,,,,,,,,LDLR_BOVIN,Bos taurus (Bovine),cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869] comp92694_c1_seq1,203,49.2611,0.32758723,6,0,,3.00E-20,P98157,Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR),GO:0005509; GO:0005905; GO:0006897; GO:0016021,calcium ion binding; coated pit; endocytosis; integral to membrane,PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;,5.00E-18,CHOYP_LRP4.5.5,,,,,,,LRP1_CHICK,Gallus gallus (Chicken),endocytosis [GO:0006897] comp92709_c0_seq1,530,46.6038,0.58184018,17,25,,2.00E-13,Q75N90,Fibrillin-3,Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide],GO:0005509; GO:0005201; GO:0005578,calcium ion binding; extracellular matrix structural constituent; proteinaceous extracellular matrix,PF12662;PF07645;PF00683;,,,,,,,,,FBN3_HUMAN,Homo sapiens (Human),anatomical structure morphogenesis [GO:0009653]; regulation of cellular response to growth factor stimulus [GO:0090287] comp92743_c0_seq1,341,41.9355,1.0729504,3,14,,5.00E-26,Q90308,Vasoactive intestinal polypeptide receptor (VIP receptor) (VIP-R),Vasoactive intestinal polypeptide receptor (VIP receptor) (VIP-R),GO:0016021; GO:0005886; GO:0004999,integral to membrane; plasma membrane; vasoactive intestinal polypeptide receptor activity,PF00002;PF02793;,,,2.00E-11,ruditapes_c11349,,,,,VIPR_CARAU,Carassius auratus (Goldfish),cell surface receptor signaling pathway [GO:0007166] comp92753_c0_seq1,228,35.5263,0.75929843,8,4,,2.00E-06,Q9H0J9,Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),GO:0003950; GO:0046872; GO:0005634,NAD+ ADP-ribosyltransferase activity; metal ion binding; nucleus,PF00644;PF02825;PF00642;,,,,,,,,,PAR12_HUMAN,Homo sapiens (Human), comp92757_c0_seq1,473,40.1691,0.21017719,18,60,,3.00E-06,Q9UK28,Transmembrane protein 59-like (Brain-specific membrane-anchored protein),Transmembrane protein 59-like (Brain-specific membrane-anchored protein),GO:0000139; GO:0016021,Golgi membrane; integral to membrane,PF12280;,3.00E-12,CHOYP_LOC100377241.1.1,,,,,,,TM59L_HUMAN,Homo sapiens (Human), comp92765_c0_seq1,208,40.8654,0.58251068,0,15,,3.00E-07,Q62255,Sal-like protein 3 (MSal) (Spalt-like protein 3),Sal-like protein 3 (MSal) (Spalt-like protein 3),GO:0003677; GO:0035136; GO:0035137; GO:0046872; GO:0045879; GO:0005634; GO:0021891; GO:0006355; GO:0006351,"DNA binding; forelimb morphogenesis; hindlimb morphogenesis; metal ion binding; negative regulation of smoothened signaling pathway; nucleus; olfactory bulb interneuron development; regulation of transcription, DNA-dependent; transcription, DNA-dependent",,,,,,,,,,SALL3_MOUSE,Mus musculus (Mouse),"forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]" comp92765_c1_seq1,419,38.6635,0.64645589,3,8,,4.00E-30,Q96PQ6,Zinc finger protein 317,Zinc finger protein 317,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN317_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp92765_c1_seq2,359,38.4401,0.68412693,0,0,,5.00E-18,P39413,Adult enhancer factor 1 (AEF-1),Adult enhancer factor 1 (AEF-1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,AEF1_DROME,Drosophila melanogaster (Fruit fly),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp92766_c0_seq1,211,62.0853,1.24124568,0,2,,2.00E-06,Q04849,Nitrogen assimilation regulatory protein NtrX,Nitrogen assimilation regulatory protein NtrX,GO:0005524; GO:0035556; GO:0009399; GO:0017111; GO:0000156; GO:0006355; GO:0043565; GO:0006351,"ATP binding; intracellular signal transduction; nitrogen fixation; nucleoside-triphosphatase activity; phosphorelay response regulator activity; regulation of transcription, DNA-dependent; sequence-specific DNA binding; transcription, DNA-dependent",PF02954;PF00072;PF00158;,,,,,,,,,NTRX_AZOC5,Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571),"nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp92771_c0_seq1,201,46.7662,0.27483673,8,5,,1.00E-10,Q5VW38,Protein GPR107 (Lung seven transmembrane receptor 1),Protein GPR107 (Lung seven transmembrane receptor 1),GO:0016021,integral to membrane,PF06814;,,,,,,,,,GP107_HUMAN,Homo sapiens (Human),clathrin-mediated endocytosis [GO:0072583] comp92781_c0_seq1,231,59.3074,1.03882544,0,6,,1.00E-06,Q9X909,DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme),DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme),GO:0005524; GO:0003677; GO:0003917; GO:0006265; GO:0046872,ATP binding; DNA binding; DNA topoisomerase type I activity; DNA topological change; metal ion binding,PF01131;PF01751;PF13368;,,,,,,,,,TOP1_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),DNA topological change [GO:0006265] comp92825_c0_seq1,429,34.965,0.38558316,4,21,,1.00E-16,Q641A2,Protein EFR3 homolog A (Protein EFR3-like),Protein EFR3 homolog A (Protein EFR3-like),GO:0005886,plasma membrane,,1.00E-29,CHOYP_EFR3B.1.1,,,,,,,EFR3A_XENLA,Xenopus laevis (African clawed frog),establishment of protein localization to plasma membrane [GO:0090002] comp92833_c0_seq1,264,33.3333,0.55008573,5,45,,,,,,,,,,,1.00E-11,ruditapes2_c2944,,,,,,, comp92847_c0_seq1,477,36.6876,0.31241967,4,10,,4.00E-15,Q09225,Nose resistant to fluoxetine protein 6 (Protein nrf-6),Nose resistant to fluoxetine protein 6 (Protein nrf-6),GO:0016021; GO:0008289; GO:0006869; GO:0007275; GO:0016747,"integral to membrane; lipid binding; lipid transport; multicellular organismal development; transferase activity, transferring acyl groups other than amino-acyl groups",PF01757;,,,,,,,,,NRF6_CAEEL,Caenorhabditis elegans,lipid transport [GO:0006869]; multicellular organism development [GO:0007275] comp92868_c1_seq1,210,61.4286,0.96372378,0,5,,3.00E-14,O81155,"Cysteine synthase, chloroplastic/chromoplastic (EC 2.5.1.47) (CSase B) (CS-B) (O-acetylserine (thiol)-lyase) (O-acetylserine sulfhydrylase) (OAS-TL B)","Cysteine synthase, chloroplastic/chromoplastic (EC 2.5.1.47) (CSase B) (CS-B) (O-acetylserine (thiol)-lyase) (O-acetylserine sulfhydrylase) (OAS-TL B)",GO:0009570; GO:0009509; GO:0006535; GO:0004124; GO:0016740,chloroplast stroma; chromoplast; cysteine biosynthetic process from serine; cysteine synthase activity; transferase activity,PF00291;,,,,,,,,,CYSKP_SOLTU,Solanum tuberosum (Potato),cysteine biosynthetic process from serine [GO:0006535] comp92875_c0_seq1,356,37.6404,0.47887702,47,57,,3.00E-38,Q6P026,Barrier-to-autointegration factor,Barrier-to-autointegration factor,GO:0003677; GO:0005694; GO:0005634,DNA binding; chromosome; nucleus,PF02961;,,,,,,,,,BAF_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp92886_c0_seq1,502,42.4303,0.44395587,12,10,,5.00E-08,Q84SL2,Zinc finger CCCH domain-containing protein 50 (OsC3H50) (Protein ZF),Zinc finger CCCH domain-containing protein 50 (OsC3H50) (Protein ZF),GO:0003677; GO:0046872,DNA binding; metal ion binding,PF12796;PF00642;,,,,,,,,,C3H50_ORYSJ,Oryza sativa subsp. japonica (Rice), comp92886_c1_seq1,531,47.8343,0.85950718,20,18,,2.00E-79,Q5FWH2,Putative E3 ubiquitin-protein ligase UNKL (EC 6.3.2.-) (RING finger protein unkempt-like),Putative E3 ubiquitin-protein ligase UNKL (EC 6.3.2.-) (RING finger protein unkempt-like),GO:0005737; GO:0016874; GO:0005634; GO:0016567; GO:0008270,cytoplasm; ligase activity; nucleus; protein ubiquitination; zinc ion binding,PF00642;,6.00E-92,CHOYP_BRAFLDRAFT_64737.1.1,,,,,,,UNKL_MOUSE,Mus musculus (Mouse), comp92904_c0_seq1,415,42.8916,0.93545517,1,20,,1.00E-10,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,,,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp92904_c0_seq2,334,44.012,0.90857072,2,0,,5.00E-09,Q7Z3T8,Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein),GO:0005545; GO:0030509; GO:0031901; GO:0016197; GO:0046872; GO:0005547; GO:0006622; GO:0008565; GO:0030100; GO:0016050,"1-phosphatidylinositol binding; BMP signaling pathway; early endosome membrane; endosomal transport; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; protein targeting to lysosome; protein transporter activity; regulation of endocytosis; vesicle organization",PF11979;PF01363;,,,,,,,,,ZFY16_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050] comp92913_c0_seq1,508,56.8898,1.10974267,0,26,,4.00E-49,Q6A5S0,Probable potassium transport system protein kup,Probable potassium transport system protein kup,GO:0016021; GO:0005886; GO:0015079,integral to membrane; plasma membrane; potassium ion transmembrane transporter activity,PF02705;,,,,,,,,,KUP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379), comp92947_c0_seq1,421,37.2922,0.62059174,7,8,,6.00E-07,Q58DK7,Zinc finger protein 205,Zinc finger protein 205,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN205_BOVIN,Bos taurus (Bovine),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp92955_c0_seq1,351,61.5385,1.15670257,2,0,,5.00E-15,B9K865,4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) (EC 4.3.3.7),4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) (EC 4.3.3.7),GO:0008840; GO:0016843; GO:0005737; GO:0019877; GO:0009089,4-hydroxy-tetrahydrodipicolinate synthase; amine-lyase activity; cytoplasm; diaminopimelate biosynthetic process; lysine biosynthetic process via diaminopimelate,PF00701;,,,,,,,,,DAPA_THENN,Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E),diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089] comp92957_c0_seq1,628,45.3822,0.46468794,29,27,,7.00E-75,Q9Y4E6,WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG),WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG),,,PF00400;,1.00E-108,CHOYP_PHUM_PHUM035190.1.1,,,,,,,WDR7_HUMAN,Homo sapiens (Human),hematopoietic progenitor cell differentiation [GO:0002244] comp92963_c0_seq1,244,48.3607,1.07082218,0,21,,1.00E-10,P98156,Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R),GO:0005509; GO:0008203; GO:0005905; GO:0005615; GO:0034436; GO:0034437; GO:0016021; GO:0006869; GO:0016020; GO:0000122; GO:1900006; GO:0045860; GO:0038025; GO:0021517; GO:0034361; GO:0034189; GO:0034447; GO:0030229,calcium ion binding; cholesterol metabolic process; coated pit; extracellular space; glycoprotein transport; glycoprotein transporter activity; integral to membrane; lipid transport; membrane; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite development; positive regulation of protein kinase activity; reelin receptor activity; ventral spinal cord development; very-low-density lipoprotein particle; very-low-density lipoprotein particle binding; very-low-density lipoprotein particle clearance; very-low-density lipoprotein particle receptor activity,PF07645;PF00057;PF00058;,,,,,,,,,VLDLR_MOUSE,Mus musculus (Mouse),cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex development [GO:0021987]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; heart development [GO:0007507]; lipid transport [GO:0006869]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] comp92968_c0_seq1,807,41.0161,0.32816473,26,45,,3.00E-65,Q9GM70,Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1) (rDRAK1),Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1) (rDRAK1),GO:0005524; GO:0006915; GO:0007243; GO:0005634; GO:0043065; GO:0004674; GO:2000377,ATP binding; apoptotic process; intracellular protein kinase cascade; nucleus; positive regulation of apoptotic process; protein serine/threonine kinase activity; regulation of reactive oxygen species metabolic process,PF00069;,2.00E-55,CHOYP_STK17A.1.1,,,,,,,ST17A_RABIT,Oryctolagus cuniculus (Rabbit),apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of reactive oxygen species metabolic process [GO:2000377] comp92973_c0_seq1,408,41.1765,0.92955104,2,27,,9.00E-06,Q6EMK4,Vasorin (Protein slit-like 2),Vasorin (Protein slit-like 2),GO:0071456; GO:0071461; GO:0005576; GO:0016021; GO:0005765; GO:0005739; GO:0005886,cellular response to hypoxia; cellular response to redox state; extracellular region; integral to membrane; lysosomal membrane; mitochondrion; plasma membrane,PF00008;PF13855;,,,,,,,,,VASN_HUMAN,Homo sapiens (Human),cellular response to hypoxia [GO:0071456]; cellular response to redox state [GO:0071461]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] comp92973_c1_seq1,448,45.0893,0.90597707,14,17,,6.00E-07,Q6R5N8,Toll-like receptor 13,Toll-like receptor 13,GO:0002755; GO:0005768; GO:0010008; GO:0006954; GO:0045087; GO:0016021; GO:0042803; GO:0019843; GO:0043408; GO:0002237; GO:0009615; GO:0034178; GO:0004888,MyD88-dependent toll-like receptor signaling pathway; endosome; endosome membrane; inflammatory response; innate immune response; integral to membrane; protein homodimerization activity; rRNA binding; regulation of MAPK cascade; response to molecule of bacterial origin; response to virus; toll-like receptor 13 signaling pathway; transmembrane signaling receptor activity,PF00560;PF13855;PF01582;,,,,,,,,,TLR13_MOUSE,Mus musculus (Mouse),defense response to other organism [GO:0098542]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; regulation of MAPK cascade [GO:0043408]; response to virus [GO:0009615]; toll-like receptor 13 signaling pathway [GO:0034178] comp92983_c0_seq1,426,41.784,0.65091822,0,0,,1.00E-12,A1YGJ4,Zinc finger protein 24,Zinc finger protein 24,GO:0046872; GO:0042552; GO:0005634; GO:0043565; GO:0003700; GO:0006351,"metal ion binding; myelination; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF02023;PF00096;,,,,,,,,,ZNF24_PANPA,Pan paniscus (Pygmy chimpanzee) (Bonobo),"myelination [GO:0042552]; transcription, DNA-templated [GO:0006351]" comp92983_c0_seq2,500,41,0.67338979,4,0,,2.00E-20,P10076,Zinc finger protein 26 (Zfp-26) (Protein mKR3),Zinc finger protein 26 (Zfp-26) (Protein mKR3),GO:0003677; GO:0046872; GO:0005634; GO:0006355,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZFP26_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]" comp92986_c0_seq1,348,47.1264,0.57102956,17,11,,4.00E-30,Q29L43,Protein MON2 homolog,Protein MON2 homolog,GO:0015031,protein transport,PF16213;PF09324;PF16206;PF12783;,1.00E-28,CHOYP_MON2.1.1,,,,,,,MON2_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),protein transport [GO:0015031] comp92990_c0_seq1,401,45.1372,0.65048948,17,17,,2.00E-19,Q9VAC5,ADAM 17-like protease (EC 3.4.24.-),ADAM 17-like protease (EC 3.4.24.-),GO:0016021; GO:0006509; GO:0004222; GO:0008270,integral to membrane; membrane protein ectodomain proteolysis; metalloendopeptidase activity; zinc ion binding,PF16698;PF00200;PF01562;,,,,,,,,,ADA17_DROME,Drosophila melanogaster (Fruit fly),membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] comp93004_c0_seq1,468,42.094,0.58674163,11,33,,6.00E-14,Q99189,mRNA transport regulator MTR10,mRNA transport regulator MTR10,GO:0006404; GO:0005737; GO:0006609; GO:0008139; GO:0005634; GO:0051031,RNA import into nucleus; cytoplasm; mRNA-binding (hnRNP) protein import into nucleus; nuclear localization sequence binding; nucleus; tRNA transport,PF08389;,,,,,,,,,MTR10_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),mRNA-binding (hnRNP) protein import into nucleus [GO:0006609]; protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404]; RNA localization [GO:0006403]; tRNA transport [GO:0051031] comp93004_c1_seq1,346,45.6647,0.50169094,5,0,,5.00E-10,Q9USZ2,Uncharacterized protein C11G11.07,Uncharacterized protein C11G11.07,GO:0006404; GO:0005829; GO:0005643; GO:0006606; GO:0008565,RNA import into nucleus; cytosol; nuclear pore; protein import into nucleus; protein transporter activity,PF03810;PF08389;,6.00E-45,CHOYP_TNPO3.1.1,,,,,,,YNR7_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404] comp93004_c2_seq1,545,40.7339,0.62451191,15,1,,1.00E-54,Q6P2B1,Transportin-3,Transportin-3,GO:0005737; GO:0005634; GO:0035048,cytoplasm; nucleus; splicing factor protein import into nucleus,PF08389;,,,,,,,,,TNPO3_MOUSE,Mus musculus (Mouse),protein import into nucleus [GO:0006606]; splicing factor protein import into nucleus [GO:0035048] comp93008_c0_seq1,401,46.8828,0.59474593,7,17,,2.00E-13,Q8BFR2,Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2),Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07648;,,,,,,,,,FSTL5_MOUSE,Mus musculus (Mouse), comp9300_c0_seq1,207,34.7826,0.96298544,7,0,,,,,,,,,5.00E-24,CHOYP_ATP6.6.6,,,,,,,,, comp93025_c0_seq1,505,46.5347,0.99476144,16,26,,9.00E-40,A2AJ76,Hemicentin-2,Hemicentin-2,GO:0005604; GO:0005509; GO:0005938; GO:0030054; GO:0050896,basement membrane; calcium ion binding; cell cortex; cell junction; response to stimulus,PF12662;PF07645;PF07474;PF07679;,,,,,,,,,HMCN2_MOUSE,Mus musculus (Mouse),response to stimulus [GO:0050896] comp93026_c0_seq1,225,44.8889,0.53428951,3,11,,1.00E-13,Q86SH2,Zygote arrest protein 1 (Oocyte-specific maternal effect factor),Zygote arrest protein 1 (Oocyte-specific maternal effect factor),GO:0005737; GO:0007275,cytoplasm; multicellular organismal development,PF13695;,,,,,,,,,ZAR1_HUMAN,Homo sapiens (Human),multicellular organism development [GO:0007275] comp93027_c0_seq1,336,44.0476,0.80238806,8,6,,2.00E-13,O62786,"Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2) (Fragment)","Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2) (Fragment)",GO:0008643; GO:0016021; GO:0022891,carbohydrate transport; integral to membrane; substrate-specific transmembrane transporter activity,PF00083;,4.00E-34,CHOYP_GTR1.1.1,,,,,,,GTR2_PIG,Sus scrofa (Pig),carbohydrate transport [GO:0008643] comp93027_c1_seq1,503,48.9066,0.86638359,28,0,,3.00E-28,Q8IRI6,Glucose transporter type 1,Glucose transporter type 1,GO:0008643; GO:0016021; GO:0022891,carbohydrate transport; integral to membrane; substrate-specific transmembrane transporter activity,PF00083;,,,,,,,,,GTR1_DROME,Drosophila melanogaster (Fruit fly),adult chitin-containing cuticle pigmentation [GO:0048085]; positive regulation of peptide hormone secretion [GO:0090277]; sensory perception of pain [GO:0019233] comp93042_c0_seq1,1273,47.7612,0.62040793,10,0,,8.00E-54,Q8N2C7,Protein unc-80 homolog,Protein unc-80 homolog,GO:0016021; GO:0034220; GO:0005886,integral to membrane; ion transmembrane transport; plasma membrane,PF15778;,2.00E-65,CHOYP_PHUM_PHUM244880.2.2,,,,,,,UNC80_HUMAN,Homo sapiens (Human),ion transmembrane transport [GO:0034220] comp93046_c0_seq1,226,42.0354,0.90560284,15,0,,2.00E-06,Q7Z408,CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2),CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00431;PF00084;,,,,,,,,,CSMD2_HUMAN,Homo sapiens (Human), comp93047_c0_seq1,266,39.4737,0.20538752,3,2,,8.00E-10,Q1ZXD6,Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5),GO:0005524; GO:0005525; GO:0005089; GO:0005622; GO:0005543; GO:0004674; GO:0035023; GO:0007264; GO:0030587,ATP binding; GTP binding; Rho guanyl-nucleotide exchange factor activity; intracellular; phospholipid binding; protein serine/threonine kinase activity; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; sorocarp development,PF16095;PF13855;PF07714;PF00621;PF08477;,,,,,,,,,ROCO5_DICDI,Dictyostelium discoideum (Slime mold),regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587] comp93095_c0_seq1,971,46.138,0.22124302,57,4,,4.00E-102,Q9P2D0,Inhibitor of Bruton tyrosine kinase (IBtk),Inhibitor of Bruton tyrosine kinase (IBtk),GO:0005737; GO:0016020; GO:0005634; GO:0019901; GO:0030292; GO:0051209,cytoplasm; membrane; nucleus; protein kinase binding; protein tyrosine kinase inhibitor activity; release of sequestered calcium ion into cytosol,PF12796;PF00651;PF00415;,7.00E-31,CHOYP_IBTK.1.1,,,,,,,IBTK_HUMAN,Homo sapiens (Human),negative regulation of protein phosphorylation [GO:0001933]; release of sequestered calcium ion into cytosol [GO:0051209] comp93104_c0_seq1,451,44.5676,0.54843546,10,28,,2.00E-75,Q6GLR7,Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),GO:0030054; GO:0030659; GO:0006887; GO:0046872; GO:0005543; GO:0015031; GO:0045202,cell junction; cytoplasmic vesicle membrane; exocytosis; metal ion binding; phospholipid binding; protein transport; synapse,PF06292;PF00169;,3.00E-101,CHOYP_LOC100372028.1.1,,,,,,,CAPS1_XENLA,Xenopus laevis (African clawed frog),dense core granule exocytosis [GO:1990504]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079] comp93111_c0_seq1,232,44.8276,0.7827693,9,10,,3.00E-33,O88572,Low-density lipoprotein receptor-related protein 6 (LRP-6),Low-density lipoprotein receptor-related protein 6 (LRP-6),GO:0044332; GO:0021874; GO:0090244; GO:0042813; GO:0090245; GO:0046849; GO:0060444; GO:0061310; GO:0061324; GO:0005901; GO:0042074; GO:0009986; GO:0071397; GO:0021587; GO:0021795; GO:0060026; GO:0015026; GO:0071936; GO:0031410; GO:0071542; GO:0005769; GO:0048596; GO:0042733; GO:0035115; GO:0035116; GO:0009880; GO:0060059; GO:0005783; GO:0035261; GO:0060325; GO:0021861; GO:0021943; GO:0001947; GO:0016021; GO:0019210; GO:0005041; GO:0060596; GO:0030901; GO:0030917; GO:0050680; GO:0045599; GO:2000151; GO:2000162; GO:2000168; GO:2000164; GO:2000166; GO:2000149; GO:0071901; GO:0034392; GO:0014029; GO:0001843; GO:0043025; GO:0042475; GO:0060021; GO:0003344; GO:2000055; GO:0043065; GO:0045780; GO:0090263; GO:0045787; GO:0002053; GO:0045778; GO:0051091; GO:0045944; GO:0036342; GO:0090009; GO:0043235; GO:0090118; GO:0060284; GO:0051593; GO:0048705; GO:0045202; GO:0007268; GO:0021794; GO:0019534; GO:0060535,Wnt receptor signaling pathway involved in dorsal/ventral axis specification; Wnt receptor signaling pathway involved in forebrain neuroblast division; Wnt receptor signaling pathway involved in somitogenesis; Wnt-activated receptor activity; axis elongation involved in somitogenesis; bone remodeling; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; caveola; cell migration involved in gastrulation; cell surface; cellular response to cholesterol; cerebellum morphogenesis; cerebral cortex cell migration; convergent extension; coreceptor activity; coreceptor activity involved in Wnt receptor signaling pathway; cytoplasmic vesicle; dopaminergic neuron differentiation; early endosome; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; endoplasmic reticulum; external genitalia morphogenesis; face morphogenesis; forebrain radial glial cell differentiation; formation of radial glial scaffolds; heart looping; integral to membrane; kinase inhibitor activity; low-density lipoprotein receptor activity; mammary placode formation; midbrain development; midbrain-hindbrain boundary development; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; negative regulation of protein serine/threonine kinase activity; negative regulation of smooth muscle cell apoptotic process; neural crest formation; neural tube closure; neuronal cell body; odontogenesis of dentin-containing tooth; palate development; pericardium morphogenesis; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of apoptotic process; positive regulation of bone resorption; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of cell cycle; positive regulation of mesenchymal cell proliferation; positive regulation of ossification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; post-anal tail morphogenesis; primitive streak formation; receptor complex; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of cell development; response to folic acid; skeletal system morphogenesis; synapse; synaptic transmission; thalamus development; toxin transporter activity; trachea cartilage morphogenesis,PF00057;PF00058;,4.00E-13,CHOYP_LRP6.3.6,,,,,,,LRP6_MOUSE,Mus musculus (Mouse),"anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" comp93112_c0_seq1,211,58.2938,0.7310509,0,9,,1.00E-15,P0AGI1,Ribose transport system permease protein RbsC,Ribose import permease protein RbsC,GO:0008643; GO:0016021; GO:0005886; GO:0005215,carbohydrate transport; integral to membrane; plasma membrane; transporter activity,PF02653;,,,,,,,,,RBSC_ECOLI,Escherichia coli (strain K12), comp93112_c1_seq1,272,60.2941,0.81214842,2,10,,2.00E-14,P44736,Ribose transport system permease protein RbsC,Ribose import permease protein RbsC,GO:0008643; GO:0016021; GO:0005886; GO:0005215,carbohydrate transport; integral to membrane; plasma membrane; transporter activity,PF02653;,,,,,,,,,RBSC_HAEIN,Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd), comp93123_c0_seq1,417,42.2062,0.70170858,0,23,,2.00E-37,P05982,NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1),NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1),GO:0003955; GO:0007568; GO:0005829; GO:0043086; GO:0043025; GO:0043525; GO:0032355; GO:0045471; GO:0007584; GO:0006979; GO:0004784; GO:0006801,NAD(P)H dehydrogenase (quinone) activity; aging; cytosol; negative regulation of catalytic activity; neuronal cell body; positive regulation of neuron apoptotic process; response to estradiol stimulus; response to ethanol; response to nutrient; response to oxidative stress; superoxide dismutase activity; superoxide metabolic process,PF02525;,,,,,,,,,NQO1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801] comp93129_c0_seq1,248,47.1774,0.51783373,2,8,,1.00E-13,Q62136,Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10),Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10),GO:0005737; GO:0005856; GO:0035335; GO:0004725,cytoplasm; cytoskeleton; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF09380;PF00373;PF09379;PF00102;,3.00E-34,CHOYP_PTPN14.1.1,,,,,,,PTN21_MOUSE,Mus musculus (Mouse), comp93166_c1_seq2,506,39.5257,0.82514817,14,0,,1.00E-12,B1WB06,Methyltransferase-like protein 24 (EC 2.1.1.-),Methyltransferase-like protein 24 (EC 2.1.1.-),GO:0005576; GO:0008168,extracellular region; methyltransferase activity,PF13383;,,,,,,,,,MET24_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp93176_c0_seq1,345,42.8986,0.39318512,7,17,,2.00E-28,Q502M6,Ankyrin repeat domain-containing protein 29,Ankyrin repeat domain-containing protein 29,,,PF00023;PF12796;,2.00E-20,CHOYP_LOC100369901.1.2,,,,,,,ANR29_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp93187_c1_seq1,1163,46.4316,0.46704981,41,23,,,,,,,,,5.00E-15,CHOYP_PHUM_PHUM219220.1.1,,,,,,,,, comp93197_c0_seq2,258,44.9612,0.3868039,0,6,,6.00E-13,Q80YR2,Protein FAM160B2 (Retinoic acid-induced protein 16),Protein FAM160B2 (Retinoic acid-induced protein 16),,,PF10257;,,,,,,,,,F16B2_MOUSE,Mus musculus (Mouse), comp93197_c0_seq3,291,43.9863,0.43036617,4,0,,2.00E-13,Q0P4Q0,Protein FAM160B2,Protein FAM160B2,,,PF10257;,,,,,,,,,F16B2_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp93214_c0_seq1,566,43.1095,0.90562783,14,13,,4.00E-09,Q8BL97,"Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7)","Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7)",GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0000166; GO:0005634; GO:0008270,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nucleotide binding; nucleus; zinc ion binding",PF00076;,,,,,,,,,SRSF7_MOUSE,Mus musculus (Mouse),"mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" comp93215_c0_seq1,345,55.942,1.03731718,0,14,,6.00E-26,Q6A9I7,Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase),Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase),GO:0005524; GO:0006241; GO:0006183; GO:0006228; GO:0005737; GO:0046872; GO:0004550,ATP binding; CTP biosynthetic process; GTP biosynthetic process; UTP biosynthetic process; cytoplasm; metal ion binding; nucleoside diphosphate kinase activity,PF00334;,,,,,,,,,NDK_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] comp93235_c0_seq1,328,41.4634,0.28765295,2,26,,9.00E-32,Q08CA1,GDP-D-glucose phosphorylase 1 (EC 2.7.7.78),GDP-D-glucose phosphorylase 1 (EC 2.7.7.78),GO:0080048; GO:0005737; GO:0006006; GO:0005085; GO:0016787; GO:0000166; GO:0016779,GDP-D-glucose phosphorylase activity; cytoplasm; glucose metabolic process; guanyl-nucleotide exchange factor activity; hydrolase activity; nucleotide binding; nucleotidyltransferase activity,,,,,,,,,,GDPP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),glucose metabolic process [GO:0006006] comp9324_c0_seq1,204,47.549,0.26215464,2,4,,8.00E-12,O00534,von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein),von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein),GO:0005634,nucleus,PF08487;PF13768;,,,,,,,,,VMA5A_HUMAN,Homo sapiens (Human), comp93283_c0_seq1,332,51.2048,0.50727506,3,4,,6.00E-17,Q5ZI89,Trafficking protein particle complex subunit 11,Trafficking protein particle complex subunit 11,GO:0005794; GO:0016192,Golgi apparatus; vesicle-mediated transport,PF11817;PF12742;,,,,,,,,,TPC11_CHICK,Gallus gallus (Chicken),vesicle-mediated transport [GO:0016192] comp93306_c0_seq1,395,46.3291,0.6622116,9,18,,,,,,,,,4.00E-16,CHOYP_LRRIQ1.1.1,,,,,,,,, comp93311_c1_seq1,373,42.0912,0.18226252,13,0,,4.00E-20,P43125,Protein retinal degeneration B (Probable calcium transporter rdgB),Protein retinal degeneration B (Probable calcium transporter rdgB),GO:0005388; GO:0016059; GO:0005887; GO:0046872; GO:0008525; GO:0046488; GO:0008526; GO:0016056; GO:0007608; GO:0016029; GO:0007601,calcium-transporting ATPase activity; deactivation of rhodopsin mediated signaling; integral to plasma membrane; metal ion binding; phosphatidylcholine transporter activity; phosphatidylinositol metabolic process; phosphatidylinositol transporter activity; rhodopsin mediated signaling pathway; sensory perception of smell; subrhabdomeral cisterna; visual perception,PF02862;PF02121;,,,,,,,,,RDGB_DROME,Drosophila melanogaster (Fruit fly),"cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; phosphatidylinositol metabolic process [GO:0046488]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]" comp93318_c0_seq1,293,50.1706,0.65994035,9,15,,3.00E-08,Q5PQL8,Protein FAM149B1,Protein FAM149B1,,,PF12516;,,,,,,,,,F149B_RAT,Rattus norvegicus (Rat), comp93318_c1_seq2,386,42.7461,0.74710926,6,6,,1.00E-08,Q8CFV2,Protein FAM149A,Protein FAM149A,,,PF12516;,2.00E-20,CHOYP_BRAFLDRAFT_130640.1.1,,,,,,,F149A_MOUSE,Mus musculus (Mouse), comp93318_c2_seq1,465,42.5806,0.52493842,17,22,,,,,,,,,6.00E-15,CHOYP_LOC100471454.1.1,,,,,,,,, comp93326_c0_seq1,390,50.2564,0.29737266,20,20,,2.00E-08,Q555C6,Putative vacuolar protein sorting-associated protein 13B,Putative vacuolar protein sorting-associated protein 13B,GO:0005794; GO:0015031,Golgi apparatus; protein transport,PF12624;PF16908;PF16909;PF16910;,6.00E-14,CHOYP_BRAFLDRAFT_88208.3.3,,,,,,,VP13B_DICDI,Dictyostelium discoideum (Slime mold),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp93326_c1_seq1,312,50.641,0.25406105,8,10,,6.00E-31,Q8BX70,Vacuolar protein sorting-associated protein 13C,Vacuolar protein sorting-associated protein 13C,,,PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;,,,,,,,,,VP13C_MOUSE,Mus musculus (Mouse),mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp93350_c0_seq1,240,42.9167,0.45644732,1,20,,5.00E-18,A6QR44,Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog),Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog),GO:0005737; GO:0003725; GO:0046872; GO:0015630; GO:0005730; GO:0031053,cytoplasm; double-stranded RNA binding; metal ion binding; microtubule cytoskeleton; nucleolus; primary miRNA processing,PF00035;,1.00E-14,CHOYP_AGAP_AGAP002554.1.1,,,,,,,DGCR8_BOVIN,Bos taurus (Bovine),primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091] comp93353_c0_seq1,507,41.2229,0.32780364,12,16,,2.00E-06,P07746,High mobility group-T protein (HMG-T) (HMG-T1) (HMG-1),High mobility group-T protein (HMG-T) (HMG-T1) (HMG-1),GO:0003677; GO:0005694; GO:0005634,DNA binding; chromosome; nucleus,PF00505;PF09011;,,,,,,,,,HMGT_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),inflammatory response [GO:0006954] comp93354_c0_seq1,795,38.1132,0.52117062,49,0,,2.00E-75,Q80TB7,Zinc finger SWIM domain-containing protein 6 (Fragment),Zinc finger SWIM domain-containing protein 6,GO:0048812; GO:2001222; GO:0008270,neuron projection morphogenesis; regulation of neuron migration; zinc ion binding,,1.00E-84,CHOYP_ZSWM5.1.1,,,,,,,ZSWM6_MOUSE,Mus musculus (Mouse),neuron projection morphogenesis [GO:0048812]; regulation of neuron migration [GO:2001222] comp93359_c1_seq1,490,46.7347,0.64856525,11,23,,8.00E-25,O42596,Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) (MDC11.2) (Metalloprotease-disintegrin MDC11b),Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) (MDC11.2) (Metalloprotease-disintegrin MDC11b),GO:0016021; GO:0004222; GO:0006508; GO:0008270,integral to membrane; metalloendopeptidase activity; proteolysis; zinc ion binding,PF08516;PF00200;PF01562;PF01421;,4.00E-18,CHOYP_AGAP_AGAP000974.1.1,,,,,,,ADA22_XENLA,Xenopus laevis (African clawed frog), comp93360_c0_seq1,389,36.2468,0.24436252,16,15,,3.00E-09,Q66KD5,Inhibitor of growth protein 3,Inhibitor of growth protein 3,GO:0043968; GO:0043967; GO:0005634; GO:0043065; GO:0040008; GO:0006355; GO:0006351; GO:0008270,"histone H2A acetylation; histone H4 acetylation; nucleus; positive regulation of apoptotic process; regulation of growth; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF12998;,,,,,,,,,ING3_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),"histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of apoptotic process [GO:0043065]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp93362_c0_seq1,515,43.8835,0.36415098,4,5,,4.00E-34,Q5T3U5,Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10),Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10),GO:0005524; GO:0006200; GO:0042626; GO:0016021; GO:0005765; GO:0005886; GO:0055085,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; lysosomal membrane; plasma membrane; transmembrane transport",PF00664;PF00005;,,,,,,,,,MRP7_HUMAN,Homo sapiens (Human),transmembrane transport [GO:0055085] comp93371_c0_seq1,548,43.2482,0.2398086,13,21,,1.00E-69,A1A5Q7,von Willebrand factor A domain-containing protein 3A,von Willebrand factor A domain-containing protein 3A,,,PF13768;,7.00E-72,CHOYP_LOC592709.1.1,,,,,,,VWA3A_RAT,Rattus norvegicus (Rat), comp93375_c0_seq1,298,41.9463,0.38333765,12,6,,2.00E-22,Q9MZD1,Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5),GO:0016021; GO:0005765; GO:0015293,integral to membrane; lysosomal membrane; symporter activity,PF07690;,,,,,,,,,S17A5_SHEEP,Ovis aries (Sheep), comp93379_c0_seq1,274,60.5839,1.047633,0,13,,5.00E-56,Q6A9R8,Glycine dehydrogenase [decarboxylating] (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase),Glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)),GO:0019464; GO:0004375; GO:0030170,glycine decarboxylation via glycine cleavage system; glycine dehydrogenase (decarboxylating) activity; pyridoxal phosphate binding,PF02347;,,,,,,,,,GCSP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glycine decarboxylation via glycine cleavage system [GO:0019464] comp93380_c0_seq1,386,46.8912,0.85076292,19,26,,2.00E-06,Q4KMG0,Cell adhesion molecule-related/down-regulated by oncogenes,Cell adhesion molecule-related/down-regulated by oncogenes,GO:0009952; GO:0007155; GO:0001708; GO:0021987; GO:0010172; GO:0060059; GO:0016021; GO:0002088; GO:0042692; GO:0007520; GO:0005886; GO:0043410; GO:0051149; GO:2000179; GO:0045666; GO:0001934; GO:0048643; GO:0051057; GO:0045944; GO:0043497; GO:0014816; GO:0007224,anterior/posterior pattern specification; cell adhesion; cell fate specification; cerebral cortex development; embryonic body morphogenesis; embryonic retina morphogenesis in camera-type eye; integral to membrane; lens development in camera-type eye; muscle cell differentiation; myoblast fusion; plasma membrane; positive regulation of MAPK cascade; positive regulation of muscle cell differentiation; positive regulation of neural precursor cell proliferation; positive regulation of neuron differentiation; positive regulation of protein phosphorylation; positive regulation of skeletal muscle tissue development; positive regulation of small GTPase mediated signal transduction; positive regulation of transcription from RNA polymerase II promoter; regulation of protein heterodimerization activity; satellite cell differentiation; smoothened signaling pathway,PF00041;PF07679;,,,,,,,,,CDON_HUMAN,Homo sapiens (Human),anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein heterodimerization activity [GO:0043497]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224] comp93386_c0_seq1,260,43.8462,0.484387,3,25,,2.00E-23,Q60575,Kinesin-like protein KIF1B,Kinesin-like protein KIF1B,GO:0005524; GO:0016887; GO:0008089; GO:0030659; GO:0009790; GO:0005871; GO:0005874; GO:0005875; GO:0008017; GO:0003777; GO:0005739; GO:0047497; GO:0007274; GO:0043005; GO:0007270; GO:0005543,ATP binding; ATPase activity; anterograde axon cargo transport; cytoplasmic vesicle membrane; embryo development; kinesin complex; microtubule; microtubule associated complex; microtubule binding; microtubule motor activity; mitochondrion; mitochondrion transport along microtubule; neuromuscular synaptic transmission; neuron projection; neuron-neuron synaptic transmission; phospholipid binding,PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;,7.00E-24,CHOYP_LOC100875479.2.2,,,,,,,KIF1B_MOUSE,Mus musculus (Mouse),anterograde axonal transport [GO:0008089]; cytoskeleton-dependent intracellular transport [GO:0030705]; embryo development [GO:0009790]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270] comp93389_c0_seq1,320,37.1875,0.63835851,6,14,,1.00E-18,Q5TB80,Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog),Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog),GO:0005879; GO:0005814; GO:0042384; GO:0005634; GO:0005886; GO:0005819,axonemal microtubule; centriole; cilium assembly; nucleus; plasma membrane; spindle,,,,,,,,,,QN1_HUMAN,Homo sapiens (Human),cilium assembly [GO:0042384] comp93394_c0_seq1,966,44.5135,0.42241876,31,3,,2.00E-80,Q9BZH6,WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15),WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15),GO:0005929; GO:0016021; GO:0005765; GO:0005634,cilium; integral to membrane; lysosomal membrane; nucleus,,6.00E-70,CHOYP_WDR11.2.2,,,,,,,WDR11_HUMAN,Homo sapiens (Human), comp93420_c0_seq2,459,49.2375,0.43505881,5,19,,6.00E-44,Q3UHE1,"Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1)","Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1)",GO:0012505; GO:0005622; GO:0008289; GO:0016020; GO:0046872; GO:0006810,endomembrane system; intracellular; lipid binding; membrane; metal ion binding; transport,PF02862;,2.00E-40,CHOYP_PITM2.2.2,,,,,,,PITM3_MOUSE,Mus musculus (Mouse),transport [GO:0006810] comp93465_c0_seq1,355,48.169,0.54103773,9,6,,2.00E-11,B0BM95,UPF0692 protein C19orf54 homolog,UPF0692 protein C19orf54 homolog,,,,,,,,,,,,CS054_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp93479_c0_seq1,327,59.9388,1.10952412,0,28,,3.00E-17,P37556,Uncharacterized protein YabN,Uncharacterized protein YabN,GO:0032259; GO:0008168,methylation; methyltransferase activity,PF03819;PF00590;,,,,,,,,,YABN_BACSU,Bacillus subtilis (strain 168),dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; dTTP catabolic process [GO:0046076]; dUTP catabolic process [GO:0046081]; TTP catabolic process [GO:0046047]; UTP catabolic process [GO:0046052] comp93487_c0_seq1,245,38.7755,0.98227014,3,0,,3.00E-12,P15145,Aminopeptidase N (AP-N) (pAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (gp130) (CD antigen CD13),Aminopeptidase N (AP-N) (pAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (gp130) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0019048; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; modulation by virus of host morphology or physiology; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_PIG,Sus scrofa (Pig),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp93492_c1_seq1,240,60.8333,1.27011428,0,19,,1.00E-14,O32215,Helicase IV (EC 3.6.4.12),Helicase IV (EC 3.6.4.12),GO:0005524; GO:0004003; GO:0003677; GO:0005737,ATP binding; ATP-dependent DNA helicase activity; DNA binding; cytoplasm,PF00580;PF13538;,,,,,,,,,HELD_BACSU,Bacillus subtilis (strain 168), comp93514_c0_seq1,533,44.6529,0.30175991,20,20,,5.00E-15,Q7Z7G8,Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1),GO:0015031,protein transport,PF12624;PF06650;PF16909;,3.00E-20,CHOYP_LOC100371084.3.4,,,,,,,VP13B_HUMAN,Homo sapiens (Human),protein transport [GO:0015031] comp93521_c1_seq1,1052,42.3954,0.53284129,44,34,,4.00E-32,P21369,Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase),Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase),GO:0008936; GO:0019363,nicotinamidase activity; pyridine nucleotide biosynthetic process,PF00857;,1.00E-52,CHOYP_LOC100374320.1.1,,,,,,,PNCA_ECOLI,Escherichia coli (strain K12),NAD metabolic process [GO:0019674]; nicotinamide metabolic process [GO:0006769]; pyridine nucleotide biosynthetic process [GO:0019363] comp93535_c0_seq1,330,51.2121,1.31836204,0,18,,5.00E-21,P46317,Lichenan permease IIC component (EIIC-Lic) (PTS system lichenan-specific EIIC component),Lichenan permease IIC component (EIIC-Lic) (PTS system lichenan-specific EIIC component),GO:0016021; GO:0009401; GO:0005886; GO:0008982; GO:0005351,integral to membrane; phosphoenolpyruvate-dependent sugar phosphotransferase system; plasma membrane; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; sugar:hydrogen symporter activity,PF02378;,,,,,,,,,PTJC_BACSU,Bacillus subtilis (strain 168),phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401] comp93563_c0_seq1,314,68.1529,0.88051208,2,2,,3.00E-09,B7L916,Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) (EC 2.4.2.21) (N(1)-alpha-phosphoribosyltransferase),Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) (EC 2.4.2.21) (N(1)-alpha-phosphoribosyltransferase),GO:0009236; GO:0015420; GO:0008939; GO:0009163,cobalamin biosynthetic process; cobalamin-transporting ATPase activity; nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity; nucleoside biosynthetic process,PF02277;,,,,,,,,,COBT_ECO55,Escherichia coli (strain 55989 / EAEC),cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163] comp93575_c0_seq1,235,42.9787,0.27787002,3,7,,9.00E-31,A0JP70,WD repeat-containing protein 90,WD repeat-containing protein 90,,,PF05018;PF00400;,1.00E-26,CHOYP_LOC100371299.1.1,,,,,,,WDR90_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp93587_c0_seq1,202,38.6139,1.07247911,0,29,,4.00E-24,P05934,Calmodulin (CaM) (Fragment),Calmodulin (CaM) (Fragment),GO:0005509,calcium ion binding,PF13499;,,,1.00E-17,ruditapes_c2942,,,,,CALM_STRPU,Strongylocentrotus purpuratus (Purple sea urchin), comp93595_c0_seq1,258,60.0775,0.99384209,4,5,,9.00E-41,Q6A9R8,Glycine dehydrogenase [decarboxylating] (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase),Glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)),GO:0019464; GO:0004375; GO:0030170,glycine decarboxylation via glycine cleavage system; glycine dehydrogenase (decarboxylating) activity; pyridoxal phosphate binding,PF02347;,,,,,,,,,GCSP_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glycine decarboxylation via glycine cleavage system [GO:0019464] comp93602_c0_seq1,364,37.9121,0.84402571,11,20,,6.00E-14,Q6ZSB9,Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00651;PF00096;PF13912;,,,,,,,,,ZBT49_HUMAN,Homo sapiens (Human),"cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp93602_c1_seq1,253,39.9209,0.99687586,1,17,,2.00E-18,Q5VIY5,Zinc finger protein 468,Zinc finger protein 468,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN468_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp93613_c0_seq2,741,41.4305,0.82614059,1,27,,4.00E-12,Q9H251,Cadherin-23 (Otocadherin),Cadherin-23 (Otocadherin),GO:0005509; GO:0006816; GO:0016339; GO:0051480; GO:0050957; GO:0007156; GO:0016021; GO:0016020; GO:0045494; GO:0005886; GO:0050896; GO:0050953; GO:0007605; GO:0032420; GO:0007601,calcium ion binding; calcium ion transport; calcium-dependent cell-cell adhesion; cytosolic calcium ion homeostasis; equilibrioception; homophilic cell adhesion; integral to membrane; membrane; photoreceptor cell maintenance; plasma membrane; response to stimulus; sensory perception of light stimulus; sensory perception of sound; stereocilium; visual perception,PF00028;,,,,,,,,,CAD23_HUMAN,Homo sapiens (Human),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] comp93626_c0_seq1,452,51.1062,0.66035309,5,10,,8.00E-09,Q9D3J5,Ankyrin repeat domain-containing protein 22,Ankyrin repeat domain-containing protein 22,,,PF12796;,5.00E-35,CHOYP_LOC100374274.1.3,,,,,,,ANR22_MOUSE,Mus musculus (Mouse), comp93628_c1_seq1,210,41.4286,1.33971292,4,0,,,,,,,,,,,7.00E-33,ruditapes_c18688,,,,,,, comp93628_c2_seq1,395,41.2658,0.60127929,11,4,,,,,,,,,1.00E-15,CHOYP_SATB2.1.1,,,,,,,,, comp93654_c0_seq2,361,48.7535,0.51587389,1,0,,6.00E-36,P15304,Hormone-sensitive lipase (HSL) (EC 3.1.1.79),Hormone-sensitive lipase (HSL) (EC 3.1.1.79),GO:0047372; GO:0005901; GO:0008203; GO:0005829; GO:0005615; GO:0007565; GO:0033878; GO:0005811; GO:0005739; GO:0005634; GO:0042134; GO:0042493; GO:0006363; GO:0006361; GO:0019433,acylglycerol lipase activity; caveola; cholesterol metabolic process; cytosol; extracellular space; female pregnancy; hormone-sensitive lipase activity; lipid particle; mitochondrion; nucleus; rRNA primary transcript binding; response to drug; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; triglyceride catabolic process,PF07859;PF06350;,1.00E-23,CHOYP_LIPS.1.2,,,,,,,LIPS_RAT,Rattus norvegicus (Rat),cholesterol metabolic process [GO:0008203]; female pregnancy [GO:0007565]; lipid catabolic process [GO:0016042]; response to drug [GO:0042493]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation from RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433] comp93654_c1_seq3,291,53.2646,0.68891949,0,0,,7.00E-06,B1IZB8,Acetyl esterase (EC 3.1.1.-),Acetyl esterase (EC 3.1.1.-),GO:0004091; GO:0005737,carboxylesterase activity; cytoplasm,PF07859;,,,,,,,,,AES_ECOLC,Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks),metabolic process [GO:0008152] comp93668_c0_seq2,471,41.8259,0.24941985,0,9,,,,,,,,,3.00E-19,CHOYP_LOC100639879.1.1,,,,,,,,, comp93693_c0_seq1,413,46.247,0.81980679,12,10,,,,,,,,,4.00E-23,CHOYP_SLC16A12.1.1,,,,,,,,, comp93698_c1_seq1,267,43.0712,0.57723887,0,6,,4.00E-08,Q54IT3,Probable flavin-containing monoamine oxidase A (EC 1.4.3.4),Probable flavin-containing monoamine oxidase A (EC 1.4.3.4),GO:0016491,oxidoreductase activity,PF01593;,,,,,,,,,AOFA_DICDI,Dictyostelium discoideum (Slime mold), comp93703_c0_seq1,849,44.2874,0.58674725,29,2,,2.00E-50,Q6DHN0,Transmembrane protein 53,Transmembrane protein 53,GO:0016021,integral to membrane,PF05705;,,,,,,,,,TMM53_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp93709_c0_seq1,541,47.5046,0.73915452,12,17,,1.00E-90,Q5BL07,Peroxisome biogenesis factor 1 (Peroxin-1),Peroxisome biogenesis factor 1 (Peroxin-1),GO:0005524; GO:0042623; GO:0005829; GO:0008289; GO:0060152; GO:0005634; GO:0005778; GO:0005777; GO:0016558,"ATP binding; ATPase activity, coupled; cytosol; lipid binding; microtubule-based peroxisome localization; nucleus; peroxisomal membrane; peroxisome; protein import into peroxisome matrix",PF00004;PF09262;PF09263;,8.00E-103,CHOYP_LOC592476.1.1,,,,,,,PEX1_MOUSE,Mus musculus (Mouse),microtubule-based peroxisome localization [GO:0060152]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein targeting to peroxisome [GO:0006625] comp93730_c0_seq1,1424,36.7275,1.0948587,431,3032,,,,,,,,,,,3.00E-47,ruditapes_c30255,,,,,,, comp93737_c0_seq2,504,45.8333,0.53528375,8,0,,1.00E-21,Q6P1U0,Protein downstream neighbor of son homolog,Protein downstream neighbor of son homolog,GO:0007049; GO:0051301; GO:0007275; GO:0005634,cell cycle; cell division; multicellular organismal development; nucleus,,,,,,,,,,DONS_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),cell cycle [GO:0007049]; cell division [GO:0051301]; multicellular organism development [GO:0007275] comp93738_c0_seq1,217,40.553,0.24022549,11,6,,2.00E-23,Q9W352,PHD finger and CXXC domain-containing protein CG17446,CXXC-type zinc finger protein 1 (PHD finger and CXXC domain-containing protein 1),GO:0003677; GO:0048188; GO:0051568; GO:0006355; GO:0006351; GO:0008270,"DNA binding; Set1C/COMPASS complex; histone H3-K4 methylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF00628;PF12269;,8.00E-16,CHOYP_LOC590665.1.1,,,,,,,Y7446_DROME,Drosophila melanogaster (Fruit fly),"histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp9373_c0_seq1,239,41.841,0.50442245,2,3,,8.00E-08,Q5F3F5,LMBR1 domain-containing protein 2,LMBR1 domain-containing protein 2,GO:0016021,integral to membrane,PF04791;,,,,,,,,,LMBD2_CHICK,Gallus gallus (Chicken), comp93744_c0_seq1,852,32.8638,0.62198002,12,55,,,,,,,,,1.00E-21,CHOYP_LOC100373789.1.2,,,,,,,,, comp93752_c0_seq1,396,42.9293,0.66863584,14,12,,6.00E-12,Q10901,Excitatory amino acid transporter (Sodium-dependent glutamate/ aspartate transporter),Excitatory amino acid transporter (Sodium-dependent glutamate/ aspartate transporter),GO:0005313; GO:0042995; GO:0016021; GO:0005886; GO:0017153,L-glutamate transmembrane transporter activity; cell projection; integral to membrane; plasma membrane; sodium:dicarboxylate symporter activity,PF00375;,,,,,,,,,EAA1_CAEEL,Caenorhabditis elegans, comp93753_c0_seq1,409,38.1418,0.67668337,7,17,,9.00E-55,Q8K394,Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2),Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2),GO:0005509; GO:0005737; GO:0035556; GO:0006629; GO:0004435; GO:0005543; GO:0004871,calcium ion binding; cytoplasm; intracellular signal transduction; lipid metabolic process; phosphatidylinositol phospholipase C activity; phospholipid binding; signal transducer activity,PF00168;PF09279;PF16457;PF00388;PF00387;,1.00E-68,CHOYP_PLCL2.1.1,,,,,,,PLCL2_MOUSE,Mus musculus (Mouse),"B-1a B cell differentiation [GO:0002337]; B cell proliferation involved in immune response [GO:0002322]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; positive regulation of receptor binding [GO:1900122]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of synaptic transmission, GABAergic [GO:0032228]" comp93753_c1_seq1,363,39.9449,0.71738818,5,7,,1.00E-36,Q1RML2,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1)","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1)",GO:0005509; GO:0035556; GO:0016042; GO:0007275; GO:0005634; GO:0048471; GO:0004435; GO:0004871; GO:0007338,calcium ion binding; intracellular signal transduction; lipid catabolic process; multicellular organismal development; nucleus; perinuclear region of cytoplasm; phosphatidylinositol phospholipase C activity; signal transducer activity; single fertilization,PF00168;PF09279;PF00388;PF00387;,2.00E-13,CHOYP_FUCTA.2.4,5.00E-19,ruditapes2_c2698,,,,,PLCZ1_BOVIN,Bos taurus (Bovine),calcium ion transport [GO:0006816]; egg activation [GO:0007343]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; multicellular organism development [GO:0007275] comp93755_c0_seq1,951,39.1167,0.6959886,927,1613,,3.00E-62,B2KI79,Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1),Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1),GO:0047874; GO:0005789; GO:0016021; GO:0006486,dolichyldiphosphatase activity; endoplasmic reticulum membrane; integral to membrane; protein glycosylation,PF01569;,8.00E-49,CHOYP_BRAFLDRAFT_131792.1.1,,,,,,,DOPP1_RHIFE,Rhinolophus ferrumequinum (Greater horseshoe bat),protein glycosylation [GO:0006486] comp93766_c0_seq1,297,42.4242,0.45152027,9,0,,1.00E-24,Q86I06,Probable serine/threonine-protein kinase nek3 (EC 2.7.11.1) (Never in mitosis protein A-related protein kinase 3) (NimA-related protein kinase 3),Probable serine/threonine-protein kinase nek3 (EC 2.7.11.1) (Never in mitosis protein A-related protein kinase 3) (NimA-related protein kinase 3),GO:0005524; GO:0004674,ATP binding; protein serine/threonine kinase activity,PF00069;,,,1.00E-13,ruditapes_c11141,,,,,NEK3_DICDI,Dictyostelium discoideum (Slime mold), comp93767_c4_seq1,337,46.8843,0.61505918,12,3,,5.00E-07,Q8N2F6,Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein),Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein),GO:0005789; GO:0016021; GO:0005739; GO:0040008,endoplasmic reticulum membrane; integral to membrane; mitochondrion; regulation of growth,PF04826;,1.00E-21,CHOYP_LOC100165581.1.1,,,,,,,ARM10_HUMAN,Homo sapiens (Human),regulation of growth [GO:0040008] comp93783_c0_seq2,204,72.0588,1.15387388,0,14,,5.00E-10,P23485,Protein FecR,Protein FecR,GO:0006811; GO:0055072; GO:0042597; GO:0050896,ion transport; iron ion homeostasis; periplasmic space; response to stimulus,PF16220;PF16344;PF04773;,,,,,,,,,FECR_ECOLI,Escherichia coli (strain K12),ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; response to stimulus [GO:0050896] comp93783_c0_seq3,261,67.8161,1.13740178,0,0,,8.00E-08,E4TJ18,Protein translocase subunit SecD,Protein translocase subunit SecD,GO:0015450; GO:0016021; GO:0065002; GO:0005886; GO:0006605; GO:0043952,P-P-bond-hydrolysis-driven protein transmembrane transporter activity; integral to membrane; intracellular protein transmembrane transport; plasma membrane; protein targeting; protein transport by the Sec complex,PF07549;PF02355;,,,,,,,,,SECD_CALNY,Calditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1),intracellular protein transmembrane transport [GO:0065002]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952] comp93786_c0_seq1,252,62.3016,1.14964485,0,19,,9.00E-51,Q6A8L5,Histidinol dehydrogenase (HDH) (EC 1.1.1.23),Histidinol dehydrogenase (HDH) (EC 1.1.1.23),GO:0051287; GO:0000105; GO:0004399; GO:0008270,NAD binding; histidine biosynthetic process; histidinol dehydrogenase activity; zinc ion binding,PF00815;,,,,,,,,,HISX_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),histidine biosynthetic process [GO:0000105] comp93805_c0_seq1,401,38.404,0.20426956,14,28,,7.00E-12,Q5XGZ9,Major facilitator superfamily domain-containing protein 6-like protein B,Major facilitator superfamily domain-containing protein 6-like protein B,GO:0016021,integral to membrane,PF12832;,2.00E-20,CHOYP_BRAFLDRAFT_275402.1.1,,,,,,,MF6LB_XENLA,Xenopus laevis (African clawed frog), comp93810_c0_seq1,333,59.7598,0.923227,0,11,,2.00E-71,Q6AAR3,L-threonine 3-dehydrogenase (EC 1.1.1.103),L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103),GO:0008743; GO:0019518; GO:0005737; GO:0008270,L-threonine 3-dehydrogenase activity; L-threonine catabolic process to glycine; cytoplasm; zinc ion binding,PF08240;PF00107;,,,,,,,,,TDH_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),L-threonine catabolic process to glycine [GO:0019518] comp93810_c1_seq1,288,62.5,0.92812384,0,12,,3.00E-36,B1VWE7,L-threonine 3-dehydrogenase (EC 1.1.1.103),L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103),GO:0008743; GO:0019518; GO:0005737; GO:0008270,L-threonine 3-dehydrogenase activity; L-threonine catabolic process to glycine; cytoplasm; zinc ion binding,PF08240;PF00107;,,,,,,,,,TDH_STRGG,Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350),L-threonine catabolic process to glycine [GO:0019518] comp93819_c0_seq1,573,45.0262,0.17629046,12,15,,1.00E-75,Q149N8,"E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)","E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)",GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0016874; GO:0000786; GO:0006334; GO:0005634; GO:0016567; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; ligase activity; nucleosome; nucleosome assembly; nucleus; protein ubiquitination; zinc ion binding,PF00271;PF00538;PF00176;,1.00E-68,CHOYP_SHPRH.1.3,,,,,,,SHPRH_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] comp93830_c1_seq1,409,45.9658,0.28568281,6,9,,7.00E-24,Q9NVE5,Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40),GO:0008234; GO:0004221; GO:0006511,cysteine-type peptidase activity; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF00443;,,,,,,,,,UBP40_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp93837_c0_seq1,221,37.5566,0.90350687,3,0,,2.00E-11,Q01H84,Selenoprotein N (SelN),Selenoprotein N (SelN),GO:0016021,integral to membrane,,,,,,,,,,SELN_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),skeletal muscle fiber development [GO:0048741] comp93856_c0_seq1,471,40.9766,0.10150583,12,25,,5.00E-06,O60290,Zinc finger protein 862,Zinc finger protein 862,GO:0046872; GO:0003676; GO:0005634; GO:0006355; GO:0006351,"metal ion binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF05699;PF01352;,,,,,,,,,ZN862_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp93867_c0_seq1,883,40.0906,1.16765614,903,0,,1.00E-08,Q3V2K1,Uncharacterized protein CXorf65 homolog,Uncharacterized protein CXorf65 homolog,,,,,,,,,,,,CX065_MOUSE,Mus musculus (Mouse), comp93889_c0_seq1,279,47.6703,1.21462748,0,20,,6.00E-16,Q96MM6,Heat shock 70 kDa protein 12B,Heat shock 70 kDa protein 12B,GO:0005524,ATP binding,,2.00E-13,CHOYP_LOC100207121.7.9,,,,,,,HS12B_HUMAN,Homo sapiens (Human), comp93892_c0_seq1,354,46.3277,0.55469193,4,3,,1.00E-07,O14299,MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase kinase kinase wak1) (MAP kinase kinase kinase wik1),MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase kinase kinase wak1) (MAP kinase kinase kinase wik1),GO:0005524; GO:0004709; GO:0051519; GO:0005829; GO:0007346; GO:0051403,ATP binding; MAP kinase kinase kinase activity; activation of bipolar cell growth; cytosol; regulation of mitotic cell cycle; stress-activated MAPK cascade,PF00069;,1.00E-16,CHOYP_LOC101174856.1.1,,,,,,,WIS4_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),MAPK cascade [GO:0000165]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403]; stress-activated protein kinase signaling cascade [GO:0031098] comp93892_c0_seq2,487,46.6119,0.53035467,5,3,,1.00E-17,Q9Y6R4,Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4),GO:0005524; GO:0007254; GO:0004709; GO:0060718; GO:0005737; GO:0019100; GO:0046872; GO:0048471; GO:0001890; GO:0043507; GO:0010468,ATP binding; JNK cascade; MAP kinase kinase kinase activity; chorionic trophoblast cell differentiation; cytoplasm; male germ-line sex determination; metal ion binding; perinuclear region of cytoplasm; placenta development; positive regulation of JUN kinase activity; regulation of gene expression,PF00069;,,,,,,,,,M3K4_HUMAN,Homo sapiens (Human),activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] comp93907_c0_seq1,744,42.0699,1.37383713,2,0,,1.00E-25,B6E465,FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,,,,,,,,,FMRF_LOLPE,Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii),neuropeptide signaling pathway [GO:0007218] comp93907_c0_seq2,661,40.2421,1.38664095,9,8,,7.00E-33,P08021,FMRF-amide neuropeptides [Cleaved into: FLRF-amide; FMRF-amide],FMRF-amide neuropeptides [Cleaved into: FLRF-amide; FMRF-amide],GO:0005576; GO:0007218,extracellular region; neuropeptide signaling pathway,PF01581;,5.00E-24,CHOYP_FMRF.3.4,,,,,,,FMRF_APLCA,Aplysia californica (California sea hare),neuropeptide signaling pathway [GO:0007218] comp93919_c1_seq1,378,44.4444,0.21860283,12,18,,2.00E-60,Q63448,Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase),Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase),GO:0003995; GO:0033540; GO:0005504; GO:0050660; GO:0005777; GO:0016402,acyl-CoA dehydrogenase activity; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid binding; flavin adenine dinucleotide binding; peroxisome; pristanoyl-CoA oxidase activity,PF01756;PF00441;PF02770;,4.00E-54,CHOYP_ACOX3.1.1,,,,,,,ACOX3_RAT,Rattus norvegicus (Rat),fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088] comp93935_c0_seq1,608,41.9408,0.86645044,16,22,,4.00E-43,Q8BGF9,Solute carrier family 25 member 44,Solute carrier family 25 member 44,GO:0016021; GO:0005743; GO:0005739; GO:0055085,integral to membrane; mitochondrial inner membrane; mitochondrion; transmembrane transport,PF00153;,,,,,,,,,S2544_MOUSE,Mus musculus (Mouse),translation [GO:0006412]; transmembrane transport [GO:0055085] comp93949_c0_seq2,571,43.7828,0.58757242,8,13,,5.00E-09,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp9394_c0_seq1,226,37.6106,0.75921219,6,0,,1.00E-09,B0M0P8,Ras guanine nucleotide exchange factor L (RasGEF domain-containing protein L),Ras guanine nucleotide exchange factor L (RasGEF domain-containing protein L),GO:0030036; GO:0005085; GO:0005622; GO:0046956; GO:0051056; GO:0007264; GO:0030587; GO:0043052,actin cytoskeleton organization; guanyl-nucleotide exchange factor activity; intracellular; positive phototaxis; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; sorocarp development; thermotaxis,PF06371;PF13855;PF00617;PF00618;,,,,,,,,,GEFL_DICDI,Dictyostelium discoideum (Slime mold),actin cytoskeleton organization [GO:0030036]; positive phototaxis [GO:0046956]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052] comp93950_c0_seq1,492,51.0163,0.77617744,6,15,,2.00E-93,Q80Y24,Prickle-like protein 2,Prickle-like protein 2,GO:0016327; GO:0045197; GO:0016328; GO:0031175; GO:0031965; GO:0008270,apicolateral plasma membrane; establishment or maintenance of epithelial cell apical/basal polarity; lateral plasma membrane; neuron projection development; nuclear membrane; zinc ion binding,PF00412;PF06297;,3.00E-82,CHOYP_LOC100329052.1.1,,,,,,,PRIC2_MOUSE,Mus musculus (Mouse),blastocyst formation [GO:0001825]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; neuron projection development [GO:0031175]; trophectodermal cell fate commitment [GO:0001830] comp93955_c1_seq1,397,44.3325,0.20826924,12,18,,4.00E-53,Q4JIJ3,Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS),GO:0031419; GO:0005737; GO:0008898; GO:0008705; GO:0042558; GO:0008270,cobalamin binding; cytoplasm; homocysteine S-methyltransferase activity; methionine synthase activity; pteridine-containing compound metabolic process; zinc ion binding,PF02310;PF02607;PF02965;PF00809;PF02574;,1.00E-79,CHOYP_METH.1.1,,,,,,,METH_BOVIN,Bos taurus (Bovine),pteridine-containing compound metabolic process [GO:0042558] comp93965_c0_seq1,380,45,0.94541598,15,10,,4.00E-09,Q0V9W6,BTB/POZ domain-containing protein 6,BTB/POZ domain-containing protein 6,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD6_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp93978_c0_seq1,570,45.0877,0.51934431,13,27,,4.00E-79,O15550,Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein),Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein),GO:0000978; GO:0060070; GO:0051213; GO:0007507; GO:0051568; GO:0071558; GO:0035097; GO:0001701; GO:0048333; GO:0046872; GO:0001843; GO:0048570; GO:0003016; GO:0032525,RNA polymerase II core promoter proximal region sequence-specific DNA binding; canonical Wnt receptor signaling pathway; dioxygenase activity; heart development; histone H3-K4 methylation; histone demethylase activity (H3-K27 specific); histone methyltransferase complex; in utero embryonic development; mesodermal cell differentiation; metal ion binding; neural tube closure; notochord morphogenesis; respiratory system process; somite rostral/caudal axis specification,PF02373;PF13181;,1.00E-87,CHOYP_LOC100883412.1.1,,,,,,,KDM6A_HUMAN,Homo sapiens (Human),canonical Wnt signaling pathway [GO:0060070]; heart morphogenesis [GO:0003007]; histone H3-K4 methylation [GO:0051568]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] comp93987_c0_seq1,2048,39.6484,0.54699685,4657,54,,5.00E-08,Q11083,Uncharacterized calcium-binding protein B0563.7,Uncharacterized calcium-binding protein B0563.7,GO:0005509,calcium ion binding,PF13499;PF13833;,4.00E-12,CHOYP_LOC100186906.1.1,,,,,,,YT67_CAEEL,Caenorhabditis elegans, comp93995_c0_seq1,263,37.6426,0.3330578,3,10,,2.00E-20,Q96JA3,Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2) (hFAPP2) (Serologically defined breast cancer antigen NY-BR-86),Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2) (hFAPP2) (Serologically defined breast cancer antigen NY-BR-86),GO:0035621; GO:0005794; GO:0097001; GO:0051861; GO:0046836; GO:0017089; GO:0016020; GO:0070273; GO:0015031; GO:0005802,ER to Golgi ceramide transport; Golgi apparatus; ceramide binding; glycolipid binding; glycolipid transport; glycolipid transporter activity; membrane; phosphatidylinositol-4-phosphate binding; protein transport; trans-Golgi network,PF08718;PF00169;,1.00E-20,CHOYP_LOC100370358.1.1,,,,,,,PKHA8_HUMAN,Homo sapiens (Human),ER to Golgi ceramide transport [GO:0035621]; lipid transport [GO:0006869]; protein transport [GO:0015031] comp93996_c1_seq1,447,39.1499,0.76190858,5,14,,2.00E-36,Q2WEA5,Transient receptor potential cation channel subfamily M member 1 (Melastatin-1),Transient receptor potential cation channel subfamily M member 1 (Melastatin-1),GO:0007216; GO:0005262; GO:0060402; GO:0016021; GO:0005886,G-protein coupled glutamate receptor signaling pathway; calcium channel activity; calcium ion transport into cytosol; integral to membrane; plasma membrane,PF00520;PF16519;,3.00E-56,CHOYP_TRPM3.6.7,,,,,,,TRPM1_RAT,Rattus norvegicus (Rat),calcium ion transport into cytosol [GO:0060402]; cellular response to light stimulus [GO:0071482]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; protein tetramerization [GO:0051262] comp94012_c0_seq1,204,46.5686,0.74075854,1,7,,1.00E-16,O08863,Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Inhibitor of apoptosis protein 1) (IAP-1) (mIAP-1) (mIAP1),Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 2) (C-IAP2) (Inhibitor of apoptosis protein 1) (mIAP1),GO:0006915; GO:0005737; GO:0070266; GO:0060546; GO:0042326; GO:2000378; GO:0005634; GO:0016567; GO:0042981; GO:0004842; GO:0008270,apoptotic process; cytoplasm; necroptosis; negative regulation of necroptosis; negative regulation of phosphorylation; negative regulation of reactive oxygen species metabolic process; nucleus; protein ubiquitination; regulation of apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00653;PF00619;,,,,,,,,,BIRC3_MOUSE,Mus musculus (Mouse),inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of necroptotic process [GO:0060546]; negative regulation of phosphorylation [GO:0042326]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of protein ubiquitination [GO:0031398]; regulation of apoptotic process [GO:0042981]; regulation of necroptotic process [GO:0060544]; regulation of toll-like receptor signaling pathway [GO:0034121] comp94012_c1_seq1,270,50,0.54200743,2,12,,2.00E-19,A9ULZ2,Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B),GO:0043027; GO:0005737; GO:0016874; GO:0007275; GO:0043066; GO:0051865; GO:0008270,cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cytoplasm; ligase activity; multicellular organismal development; negative regulation of apoptotic process; protein autoubiquitination; zinc ion binding,PF00653;,,,2.00E-15,ruditapes2_c1114,,,,,BIR7B_XENLA,Xenopus laevis (African clawed frog),multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865] comp94012_c2_seq2,268,44.403,0.61768943,3,7,,,,,,,,,,,4.00E-12,ruditapes_c8366,,,,,,, comp94030_c0_seq2,348,38.5057,0.39302126,2,0,,,,,,,,,4.00E-28,CHOYP_CLN3.1.2,,,,,,,,, comp94031_c0_seq1,217,45.1613,1.39033565,6,0,,1.00E-07,O53454,3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (Cholesterol dehydrogenase) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (3-beta-HSD) (3BHSD) (EC 1.1.1.145) (3-beta hydroxysterol dehydrogenase) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)],,GO:0003854; GO:0070403; GO:0005829; GO:0016042; GO:0005886; GO:0006694; GO:0004769; GO:0008202; GO:0030283,3-beta-hydroxy-delta5-steroid dehydrogenase activity; NAD+ binding; cytosol; lipid catabolic process; plasma membrane; steroid biosynthetic process; steroid delta-isomerase activity; steroid metabolic process; testosterone dehydrogenase [NAD(P)] activity,,,,,,,,,,3BHS_MYCTU,, comp94032_c0_seq1,283,61.1307,1.21563851,1,24,,7.00E-14,Q9KK89,Phosphate-binding protein PstS 3 (PBP 3) (PstS-3),Phosphate-binding protein PstS 3 (PBP 3) (PstS-3),GO:0043190; GO:0042301; GO:0035435; GO:0005886,ATP-binding cassette (ABC) transporter complex; phosphate ion binding; phosphate ion transmembrane transport; plasma membrane,PF12849;,,,,,,,,,PSTS3_MYCAV,Mycobacterium avium,phosphate ion transmembrane transport [GO:0035435] comp94043_c0_seq1,255,44.3137,0.84322772,1,1,,1.00E-07,P37302,Aminopeptidase Y (EC 3.4.11.15),Aminopeptidase Y (EC 3.4.11.15),GO:0004177; GO:0000324; GO:0008237; GO:0006508; GO:0007039,aminopeptidase activity; fungal-type vacuole; metallopeptidase activity; proteolysis; vacuolar protein catabolic process,PF02225;PF04389;,,,,,,,,,APE3_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),protein catabolic process in the vacuole [GO:0007039] comp94054_c0_seq1,300,45,0.13230916,3,7,,6.00E-23,Q91V01,Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5),Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5),GO:0047184; GO:0005789; GO:0016021; GO:0008654; GO:0097006,1-acylglycerophosphocholine O-acyltransferase activity; endoplasmic reticulum membrane; integral to membrane; phospholipid biosynthetic process; regulation of plasma lipoprotein particle levels,PF03062;,7.00E-12,CHOYP_LPCAT3-A.1.1,,,,,,,MBOA5_MOUSE,Mus musculus (Mouse),phospholipid biosynthetic process [GO:0008654]; regulation of plasma lipoprotein particle levels [GO:0097006] comp94067_c0_seq1,289,49.481,1.25001497,3,2,,8.00E-14,P57787,Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3),Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3),GO:0015629; GO:0016021; GO:0031965; GO:0005886; GO:0015355; GO:0015293,actin cytoskeleton; integral to membrane; nuclear membrane; plasma membrane; secondary active monocarboxylate transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT4_MOUSE,Mus musculus (Mouse),plasma membrane lactate transport [GO:0035879] comp94084_c2_seq1,275,40.3636,0.18039454,3,13,,1.00E-10,P17022,Zinc finger protein 18 (Heart development-specific gene 1 protein) (Zinc finger protein 535) (Zinc finger protein KOX11) (Zinc finger protein with KRAB and SCAN domains 6),Zinc finger protein 18 (Heart development-specific gene 1 protein) (Zinc finger protein 535) (Zinc finger protein KOX11) (Zinc finger protein with KRAB and SCAN domains 6),GO:0003677; GO:0046872; GO:0005634; GO:0000981,DNA binding; metal ion binding; nucleus; sequence-specific DNA binding RNA polymerase II transcription factor activity,PF01352;PF02023;PF00096;,,,,,,,,,ZNF18_HUMAN,Homo sapiens (Human),"transcription, DNA-templated [GO:0006351]" comp94101_c0_seq1,324,32.0988,0.61205856,14,22,,5.00E-09,P14381,Transposon TX1 uncharacterized 149 kDa protein (ORF 2),Transposon TX1 uncharacterized 149 kDa protein (ORF 2),GO:0003723; GO:0006278; GO:0003964,RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity,PF03372;PF00078;,1.00E-22,CHOYP_LOC100562878.2.2,,,,,,,YTX2_XENLA,Xenopus laevis (African clawed frog), comp94175_c0_seq1,737,40.0271,0.61177233,348,2340,,4.00E-27,Q767K8,"28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2)","28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2)",GO:0005739; GO:0005840; GO:0003735; GO:0006412,mitochondrion; ribosome; structural constituent of ribosome; translation,PF01084;,,,6.00E-15,ruditapes_c20067,,,,,RT18B_PIG,Sus scrofa (Pig),translation [GO:0006412] comp94181_c0_seq1,697,44.0459,0.47767421,31,4,,2.00E-48,Q55E58,Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),GO:0005524; GO:0005525; GO:0042641; GO:0000281; GO:0004721; GO:0006470; GO:0004674; GO:0007264,ATP binding; GTP binding; actomyosin; mitotic cytokinesis; phosphoprotein phosphatase activity; protein dephosphorylation; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF16095;PF06602;PF07714;PF08477;,5.00E-37,CHOYP_TRIADDRAFT_57945.2.3,,,,,,,PATS1_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176] comp94183_c0_seq1,384,42.7083,1.37500932,11,5,,1.00E-09,Q99715,Collagen alpha-1(XII) chain,Collagen alpha-1(XII) chain,GO:0007155; GO:0030574; GO:0030199; GO:0005595; GO:0005788; GO:0022617; GO:0030020; GO:0005615; GO:0070062; GO:0001501,cell adhesion; collagen catabolic process; collagen fibril organization; collagen type XII; endoplasmic reticulum lumen; extracellular matrix disassembly; extracellular matrix structural constituent conferring tensile strength; extracellular space; extracellular vesicular exosome; skeletal system development,PF01391;PF00041;PF00092;,,,,,,,,,COCA1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987]; skeletal system development [GO:0001501] comp94194_c0_seq1,287,49.8258,0.51429196,4,17,,1.00E-41,Q5TC82,Roquin-1 (Roquin) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198),Roquin-1 (Roquin) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198),GO:0000932; GO:0033962; GO:0010494; GO:0003730; GO:0030889; GO:0045623; GO:0046007; GO:0002635; GO:0000956; GO:0050856; GO:0043488; GO:0004842; GO:0008270,cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; cytoplasmic stress granule; mRNA 3'-UTR binding; negative regulation of B cell proliferation; negative regulation of T-helper cell differentiation; negative regulation of activated T cell proliferation; negative regulation of germinal center formation; nuclear-transcribed mRNA catabolic process; regulation of T cell receptor signaling pathway; regulation of mRNA stability; ubiquitin-protein ligase activity; zinc ion binding,PF00642;PF13445;,2.00E-63,CHOYP_LOC558213.1.1,,,,,,,RC3H1_HUMAN,Homo sapiens (Human),"3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; cytoplasmic mRNA processing body assembly [GO:0033962]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of germinal center formation [GO:0002634]; regulation of mRNA stability [GO:0043488]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T follicular helper cell differentiation [GO:0061470]" comp94200_c1_seq2,367,47.139,0.45733562,8,15,,8.00E-21,Q9P267,Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5),Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5),GO:0003682; GO:0005694; GO:0005634,chromatin binding; chromosome; nucleus,PF00855;,,,,,,,,,MBD5_HUMAN,Homo sapiens (Human),glucose homeostasis [GO:0042593]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nervous system development [GO:0007399]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; regulation of multicellular organism growth [GO:0040014]; single-organism behavior [GO:0044708]; xenophagy [GO:0098792] comp94203_c0_seq1,366,46.4481,0.37226767,11,11,,4.00E-55,Q3TIT8,Sugar phosphate exchanger 3 (Solute carrier family 37 member 3),Sugar phosphate exchanger 3 (Solute carrier family 37 member 3),GO:0008643; GO:0016021; GO:0055085; GO:0005215,carbohydrate transport; integral to membrane; transmembrane transport; transporter activity,PF07690;,4.00E-41,CHOYP_SPX3.1.1,,,,,,,SPX3_MOUSE,Mus musculus (Mouse),anion transport [GO:0006820]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085] comp94205_c0_seq1,829,38.3595,0.9053827,46,1,,3.00E-24,O46503,Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.-) (Sulfotransferase 1C1),Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.-) (Sulfotransferase 1C1),GO:0005737; GO:0008146,cytoplasm; sulfotransferase activity,PF00685;,,,,,,,,,ST1C2_RABIT,Oryctolagus cuniculus (Rabbit),sulfation [GO:0051923] comp94220_c0_seq1,632,45.0949,0.40669273,29,11,,2.00E-37,A2BIJ3,BSD domain-containing protein 1,BSD domain-containing protein 1,,,PF03909;,9.00E-15,CHOYP_BRAFLDRAFT_88506.1.1,,,,,,,BSDC1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp94258_c0_seq1,486,43.8272,0.47281754,11,15,,3.00E-24,A8DYE2,Transient receptor potential cation channel trpm,"Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)",GO:0005261; GO:0034703; GO:0016049; GO:0070838; GO:0010960; GO:0046873; GO:0007005; GO:0055069,cation channel activity; cation channel complex; cell growth; divalent metal ion transport; magnesium ion homeostasis; metal ion transmembrane transporter activity; mitochondrion organization; zinc ion homeostasis,PF00520;PF16519;,1.00E-18,CHOYP_SMP_173720.3.3,,,,,,,TRPCG_DROME,Drosophila melanogaster (Fruit fly),cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069] comp94266_c0_seq1,204,46.5686,0.83335336,6,6,,2.00E-14,P82251,"B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)","b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)",GO:0015184; GO:0007596; GO:0006520; GO:0005887; GO:0050900; GO:0015175; GO:0042605; GO:0006461,L-cystine transmembrane transporter activity; blood coagulation; cellular amino acid metabolic process; integral to plasma membrane; leukocyte migration; neutral amino acid transmembrane transporter activity; peptide antigen binding; protein complex assembly,PF13520;,,,,,,,,,BAT1_HUMAN,Homo sapiens (Human),amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; leukocyte migration [GO:0050900]; neutral amino acid transport [GO:0015804]; protein complex assembly [GO:0006461] comp94266_c1_seq1,324,38.2716,1.26855229,12,5,,2.00E-08,Q91WN3,Solute carrier family 7 member 13 (Sodium-independent aspartate/glutamate transporter 1) (X-amino acid transporter 2),Solute carrier family 7 member 13 (Sodium-independent aspartate/glutamate transporter 1) (X-amino acid transporter 2),GO:0015171; GO:0016021,amino acid transmembrane transporter activity; integral to membrane,PF13520;,8.00E-18,CHOYP_BAT1.1.4,,,,,,,S7A13_MOUSE,Mus musculus (Mouse),neutral amino acid transport [GO:0015804] comp94269_c0_seq1,928,38.4698,0.65822943,200,961,,4.00E-08,Q9BUH6,Uncharacterized protein C9orf142,Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein),,,PF15384;,,,5.00E-56,ruditapes_c8553,,,,,CI142_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA ligation involved in DNA repair [GO:0051103]; double-strand break repair via nonhomologous end joining [GO:0006303] comp94273_c0_seq1,248,37.0968,0.4727177,9,0,,4.00E-10,Q8CJ78,Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs),Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN628_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp94277_c0_seq1,295,43.3898,0.57869678,1,20,,1.00E-18,Q16566,Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR),Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR),GO:0005524; GO:0007202; GO:0004683; GO:0005829; GO:0007173; GO:0008543; GO:0006954; GO:0045087; GO:0007616; GO:0043011; GO:0007270; GO:0048011; GO:0006913; GO:0005730; GO:0005654; GO:0046827; GO:0045893; GO:0006468; GO:0033081; GO:0045670; GO:0007268,"ATP binding; activation of phospholipase C activity; calmodulin-dependent protein kinase activity; cytosol; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; inflammatory response; innate immune response; long-term memory; myeloid dendritic cell differentiation; neuron-neuron synaptic transmission; neurotrophin TRK receptor signaling pathway; nucleocytoplasmic transport; nucleolus; nucleoplasm; positive regulation of protein export from nucleus; positive regulation of transcription, DNA-dependent; protein phosphorylation; regulation of T cell differentiation in thymus; regulation of osteoclast differentiation; synaptic transmission",PF00069;,,,,,,,,,KCC4_HUMAN,Homo sapiens (Human),"adaptive immune response [GO:0002250]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; myeloid dendritic cell differentiation [GO:0043011]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670]; regulation of T cell differentiation in thymus [GO:0033081]; signal transduction [GO:0007165]" comp94278_c0_seq1,223,48.8789,1.02609533,12,5,,,,,,,,,1.00E-51,CHOYP_RN45S.5.5,,,,,,,,, comp94280_c0_seq1,290,46.8966,0.76579858,7,14,,4.00E-07,F1NB38,Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41),Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41),GO:0016831; GO:0005829; GO:0004492,carboxy-lyase activity; cytosol; methylmalonyl-CoA decarboxylase activity,PF00378;,,,,,,,,,ECHD1_CHICK,Gallus gallus (Chicken),metabolic process [GO:0008152] comp94285_c0_seq2,272,50.7353,0.94792948,0,3,,1.00E-12,P82968,Four-domain proteases inhibitor (McaPI),Four-domain proteases inhibitor (McaPI),GO:0004867,serine-type endopeptidase inhibitor activity,PF00050;PF07648;PF00014;,,,,,,,,,MCPI_MELCP,Melithaea caledonica, comp94285_c0_seq3,291,48.11,0.88658605,0,0,,6.00E-07,P09865,Bdellin B-3 (Fragment),Bdellin B-3 (Fragment),GO:0004867,serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,IBD3_HIRME,Hirudo medicinalis (Medicinal leech), comp94285_c0_seq4,322,48.1366,0.92517899,0,0,,7.00E-07,P01005,Ovomucoid (Allergen Gal d I) (allergen Gal d 1),Ovomucoid (Allergen Gal d I) (allergen Gal d 1),GO:0019863; GO:0019864; GO:0005576; GO:0043234; GO:0004867,IgE binding; IgG binding; extracellular region; protein complex; serine-type endopeptidase inhibitor activity,PF00050;,,,,,,,,,IOVO_CHICK,Gallus gallus (Chicken), comp94291_c0_seq1,316,43.6709,0.44028219,0,0,,4.00E-16,Q9ET55,Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC),Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC),GO:0048511,rhythmic process,PF03372;,,,,,,,,,NOCT_RAT,Rattus norvegicus (Rat),circadian regulation of gene expression [GO:0032922]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of fat cell differentiation [GO:0045600]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; response to extracellular stimulus [GO:0009991]; response to lipopolysaccharide [GO:0032496] comp94291_c1_seq1,311,41.4791,0.52652425,12,8,,2.00E-06,Q24239,Protein angel (Angel 39) (ANG39),Protein angel (Angel 39) (ANG39),GO:0007275,multicellular organismal development,PF03372;,,,,,,,,,ANGEL_DROME,Drosophila melanogaster (Fruit fly),multicellular organism development [GO:0007275] comp94291_c1_seq2,400,37,0.52418628,8,0,,9.00E-21,Q9UK39,Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC),Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC),GO:0000932; GO:0033962; GO:0000290; GO:0005654; GO:0048511; GO:0003700; GO:0006366,cytoplasmic mRNA processing body; cytoplasmic mRNA processing body assembly; deadenylation-dependent decapping of nuclear-transcribed mRNA; nucleoplasm; rhythmic process; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter,PF03372;,,,,,,,,,NOCT_HUMAN,Homo sapiens (Human),circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of fat cell differentiation [GO:0045600]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; response to extracellular stimulus [GO:0009991]; response to lipopolysaccharide [GO:0032496]; transcription from RNA polymerase II promoter [GO:0006366] comp94297_c0_seq1,222,43.2432,0.48416093,0,18,,,,,,,,,6.00E-11,CHOYP_BRAFLDRAFT_80394.5.9,,,,,,,,, comp94300_c0_seq1,207,59.4203,1.05670915,1,3,,1.00E-13,Q9EUS8,Polyphosphate kinase (EC 2.7.4.1) (ATP-polyphosphate phosphotransferase) (Polyphosphoric acid kinase) (Fragment),Polyphosphate kinase (EC 2.7.4.1) (ATP-polyphosphate phosphotransferase) (Polyphosphoric acid kinase) (Fragment),GO:0005524; GO:0006799; GO:0008976; GO:0009358,ATP binding; polyphosphate biosynthetic process; polyphosphate kinase activity; polyphosphate kinase complex,PF02503;PF13090;PF13089;,,,,,,,,,PPK_STRGR,Streptomyces griseus,polyphosphate biosynthetic process [GO:0006799] comp94300_c1_seq1,223,58.296,1.11445027,0,14,,2.00E-28,Q05943,Transcriptional regulatory protein GlnR,Transcriptional regulatory protein GlnR,GO:0003677; GO:0035556; GO:0000156; GO:0006355; GO:0006351,"DNA binding; intracellular signal transduction; phosphorelay response regulator activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00486;,,,,,,,,,GLNR_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),"phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp94313_c0_seq1,619,38.6107,0.96124282,9,321,,4.00E-31,P97346,Nucleoredoxin (EC 1.8.1.8) (Protein Red-1),Nucleoredoxin (EC 1.8.1.8) (Protein Red-1),GO:0016055; GO:0072358; GO:0030154; GO:0005829; GO:0030178; GO:0031397; GO:0005634; GO:0047134; GO:0004791,Wnt receptor signaling pathway; cardiovascular system development; cell differentiation; cytosol; negative regulation of Wnt receptor signaling pathway; negative regulation of protein ubiquitination; nucleus; protein-disulfide reductase activity; thioredoxin-disulfide reductase activity,PF13905;,1.00E-12,CHOYP_LOC100633077.3.4,2.00E-20,ruditapes2_c833,,,,,NXN_MOUSE,Mus musculus (Mouse),cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] comp94329_c0_seq1,203,54.6798,0.66278411,1,4,,2.00E-10,O76082,Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2),Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2),GO:0005524; GO:0042895; GO:0016324; GO:0016323; GO:0031526; GO:0015226; GO:0015238; GO:0016021; GO:0060731; GO:0052106; GO:0006814; GO:0070715; GO:0015293,ATP binding; antibiotic transporter activity; apical plasma membrane; basolateral plasma membrane; brush border membrane; carnitine transmembrane transporter activity; drug transmembrane transporter activity; integral to membrane; positive regulation of intestinal epithelial structure maintenance; quorum sensing involved in interaction with host; sodium ion transport; sodium-dependent organic cation transport; symporter activity,PF00083;,,,,,,,,,S22A5_HUMAN,Homo sapiens (Human),carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; drug transport [GO:0015893]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; quorum sensing involved in interaction with host [GO:0052106]; sodium-dependent organic cation transport [GO:0070715]; sodium ion transport [GO:0006814] comp94333_c0_seq1,275,44.7273,0.14642103,2,10,,5.00E-32,P0C928,Regulator of telomere elongation helicase 1 (EC 3.6.4.12),Regulator of telomere elongation helicase 1 (EC 3.6.4.12),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0046872; GO:0005634,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; metal ion binding; nucleus",PF06733;PF13307;,6.00E-31,CHOYP_RTEL1.1.1,,,,,,,RTEL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723] comp94338_c0_seq2,839,39.8093,0.42386076,0,11,,2.00E-07,Q8N9B4,Ankyrin repeat domain-containing protein 42,Ankyrin repeat domain-containing protein 42,GO:0005634; GO:0051092; GO:1900017,nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production involved in inflammatory response,PF12796;,,,,,,,,,ANR42_HUMAN,Homo sapiens (Human), comp94347_c1_seq1,770,47.6623,0.41217771,21,11,,6.00E-90,Q24498,Ryanodine receptor 44F,Ryanodine receptor (Ryanodine receptor 44F),GO:0005509; GO:0006874; GO:0016021; GO:0005875; GO:0007275; GO:0006936; GO:0035206; GO:0072347; GO:0005219; GO:0033017,calcium ion binding; cellular calcium ion homeostasis; integral to membrane; microtubule associated complex; multicellular organismal development; muscle contraction; regulation of hemocyte proliferation; response to anesthetic; ryanodine-sensitive calcium-release channel activity; sarcoplasmic reticulum membrane,PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;,5.00E-107,CHOYP_LOC100643070.1.1,,,,,,,RY44_DROME,Drosophila melanogaster (Fruit fly),calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347] comp94352_c0_seq1,607,44.6458,0.70588427,2,0,,4.00E-11,Q6PNC0,DmX-like protein 1 (X-like 1 protein),DmX-like protein 1 (X-like 1 protein),,,PF12234;PF00400;,,,,,,,,,DMXL1_MOUSE,Mus musculus (Mouse), comp94352_c0_seq2,668,45.0599,0.71233523,3,0,,2.00E-13,Q8BPN8,DmX-like protein 2 (Rabconnectin-3),DmX-like protein 2 (Rabconnectin-3),GO:0030054; GO:0030672,cell junction; synaptic vesicle membrane,PF12234;PF00400;,2.00E-41,CHOYP_AGAP_AGAP010490.1.1,,,,,,,DMXL2_MOUSE,Mus musculus (Mouse), comp94362_c0_seq1,239,37.2385,0.48485697,484,682,,,,,,,,,,,3.00E-13,ruditapes_c14323,,,,,,, comp94365_c0_seq1,229,52.8384,0.88124286,2,7,,1.00E-09,Q15063,Periostin (PN) (Osteoblast-specific factor 2) (OSF-2),Periostin (PN) (Osteoblast-specific factor 2) (OSF-2),GO:0005794; GO:0007155; GO:0030198; GO:0008201; GO:0005578; GO:0008593; GO:0001501; GO:0009888,Golgi apparatus; cell adhesion; extracellular matrix organization; heparin binding; proteinaceous extracellular matrix; regulation of Notch signaling pathway; skeletal system development; tissue development,PF02469;,2.00E-24,CHOYP_BRAFLDRAFT_127065.5.7,,,,,,,POSTN_HUMAN,Homo sapiens (Human),bone regeneration [GO:1990523]; cell adhesion [GO:0007155]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vitamin K [GO:0071307]; extracellular matrix organization [GO:0030198]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neuron projection extension [GO:1990138]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of Notch signaling pathway [GO:0008593]; regulation of systemic arterial blood pressure [GO:0003073]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to muscle activity [GO:0014850]; skeletal system development [GO:0001501] comp94365_c1_seq2,323,42.4149,1.14945669,6,2,,,,,,,,,5.00E-14,CHOYP_contig_025333,,,,,,,,, comp94365_c2_seq1,342,48.2456,0.92842899,0,30,,2.00E-07,O33752,Uncharacterized protein SYNPCC7002_A0175,Uncharacterized protein SYNPCC7002_A0175,,,PF02469;,,,,,,,,,Y175_SYNP2,Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum), comp94367_c0_seq1,607,44.6458,0.38951766,16,17,,4.00E-10,Q6AY97,Coiled-coil domain-containing protein 91 (GGA-binding partner),Coiled-coil domain-containing protein 91 (GGA-binding partner),GO:0005794; GO:0016020; GO:0015031,Golgi apparatus; membrane; protein transport,,,,,,,,,,CCD91_RAT,Rattus norvegicus (Rat),protein transport [GO:0015031] comp94387_c0_seq1,392,41.3265,0.47919836,0,0,,3.00E-07,Q9ULI3,Protein HEG homolog 1,Protein HEG homolog 1,GO:0005509; GO:0003209; GO:0005911; GO:0045216; GO:0001886; GO:0009897; GO:0005576; GO:0001701; GO:0016021; GO:0030324; GO:0003017; GO:0001945; GO:0035264; GO:0060039; GO:0009791; GO:0050878; GO:0001570; GO:0048845; GO:0003281,calcium ion binding; cardiac atrium morphogenesis; cell-cell junction; cell-cell junction organization; endothelial cell morphogenesis; external side of plasma membrane; extracellular region; in utero embryonic development; integral to membrane; lung development; lymph circulation; lymph vessel development; multicellular organism growth; pericardium development; post-embryonic development; regulation of body fluid levels; vasculogenesis; venous blood vessel morphogenesis; ventricular septum development,PF00008;PF07645;,,,,,,,,,HEG1_HUMAN,Homo sapiens (Human),cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222] comp94387_c0_seq2,514,42.8016,0.73227109,12,0,,5.00E-11,O42182,Fibulin-1 (FIBL-1),Fibulin-1 (FIBL-1),GO:0005509; GO:0035122; GO:0030198; GO:0090497; GO:0005578; GO:0043589,calcium ion binding; embryonic medial fin morphogenesis; extracellular matrix organization; mesenchymal cell migration; proteinaceous extracellular matrix; skin morphogenesis,PF01821;PF12662;PF07645;,,,,,,,,,FBLN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic medial fin morphogenesis [GO:0035122]; extracellular matrix organization [GO:0030198]; mesenchymal cell migration [GO:0090497]; skin morphogenesis [GO:0043589] comp94390_c0_seq1,370,40.5405,0.72758599,7,8,,3.00E-40,Q16943,Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33),Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33),GO:0030054; GO:0016021; GO:0043005; GO:0005198; GO:0045202,cell junction; integral to membrane; neuron projection; structural molecule activity; synapse,PF00635;,6.00E-20,CHOYP_VP33.2.2,,,,,,,VP33_APLCA,Aplysia californica (California sea hare),protein localization to endoplasmic reticulum [GO:0070972] comp94393_c0_seq1,228,42.1053,0.8007147,1,19,,2.00E-14,Q8TDB6,E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2),GO:0005737; GO:0006302; GO:0042393; GO:0010390; GO:0005634; GO:0004842; GO:0008270,cytoplasm; double-strand break repair; histone binding; histone monoubiquitination; nucleus; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,DTX3L_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209] comp94395_c1_seq1,448,41.0714,0.44771506,17,0,,1.00E-18,A7E3W2,Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein),Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein),GO:0007155; GO:0070062; GO:0016020; GO:0005578; GO:0005044,cell adhesion; extracellular vesicular exosome; membrane; proteinaceous extracellular matrix; scavenger receptor activity,PF07707;PF00530;,,,,,,,,,LG3BP_BOVIN,Bos taurus (Bovine),cell adhesion [GO:0007155] comp943_c0_seq1,248,41.129,0.57462473,0,1,,3.00E-08,P15586,N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S),N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S),GO:0008449; GO:0005975; GO:0042340; GO:0043202; GO:0046872,N-acetylglucosamine-6-sulfatase activity; carbohydrate metabolic process; keratan sulfate catabolic process; lysosomal lumen; metal ion binding,PF00884;,,,,,,,,,GNS_HUMAN,Homo sapiens (Human),glycosaminoglycan catabolic process [GO:0006027]; keratan sulfate catabolic process [GO:0042340] comp94403_c0_seq1,445,48.3146,0.83002901,20,13,,1.00E-37,Q8VI56,Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan),Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan),GO:0016055; GO:0005509; GO:0030154; GO:0009953; GO:0042733; GO:0006897; GO:0001942; GO:0016021; GO:0001822; GO:0030178; GO:0090090; GO:0030279; GO:0042475; GO:0005886; GO:0042803; GO:0009954; GO:0043113; GO:0001932; GO:0051124,Wnt receptor signaling pathway; calcium ion binding; cell differentiation; dorsal/ventral pattern formation; embryonic digit morphogenesis; endocytosis; hair follicle development; integral to membrane; kidney development; negative regulation of Wnt receptor signaling pathway; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of ossification; odontogenesis of dentin-containing tooth; plasma membrane; protein homodimerization activity; proximal/distal pattern formation; receptor clustering; regulation of protein phosphorylation; synaptic growth at neuromuscular junction,PF12662;PF00057;PF00058;,4.00E-11,CHOYP_LRP4.5.5,,,,,,,LRP4_MOUSE,Mus musculus (Mouse),anatomical structure development [GO:0048856]; BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; negative regulation of Wnt signaling pathway [GO:0030178]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] comp94405_c0_seq1,543,43.4622,0.49680534,24,4,,3.00E-09,Q6AXB2,Rab9 effector protein with kelch motifs,Rab9 effector protein with kelch motifs,,,,,,,,,,,,RABEK_XENLA,Xenopus laevis (African clawed frog), comp94405_c2_seq1,288,42.7083,0.61229552,15,0,,1.00E-08,Q54C94,Ras guanine nucleotide exchange factor F (RasGEF domain-containing protein F),Ras guanine nucleotide exchange factor F (RasGEF domain-containing protein F),GO:0005085; GO:0005622; GO:0051056; GO:0007264,guanyl-nucleotide exchange factor activity; intracellular; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00617;PF00618;,,,,,,,,,GEFF_DICDI,Dictyostelium discoideum (Slime mold),small GTPase mediated signal transduction [GO:0007264] comp94408_c0_seq1,661,41.6036,0.42063,15,9,,5.00E-61,Q9UKG1,"DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)","DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)",GO:0006915; GO:0007049; GO:0008283; GO:0005829; GO:0031901; GO:0010008; GO:0008286; GO:0005634; GO:0005543; GO:0043065; GO:0090003; GO:0046324; GO:0012506,apoptotic process; cell cycle; cell proliferation; cytosol; early endosome membrane; endosome membrane; insulin receptor signaling pathway; nucleus; phospholipid binding; positive regulation of apoptotic process; regulation of establishment of protein localization to plasma membrane; regulation of glucose import; vesicle membrane,PF00169;PF00640;,6.00E-80,CHOYP_DP13A.2.3,,,,,,,DP13A_HUMAN,Homo sapiens (Human),cell cycle [GO:0007049]; cell proliferation [GO:0008283]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; insulin receptor signaling pathway [GO:0008286]; regulation of establishment of protein localization to plasma membrane [GO:0090003]; regulation of glucose import [GO:0046324]; signal transduction [GO:0007165] comp94409_c0_seq1,1112,35.5216,1.19849343,1849,119,,1.00E-29,Q4R5Y0,UPF0686 protein C11orf1 homolog,UPF0686 protein C11orf1 homolog,GO:0005634,nucleus,PF06608;,3.00E-24,CHOYP_BRAFLDRAFT_123540.1.1,,,,,,,CK001_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp94439_c1_seq1,371,38.5445,0.37943972,9,16,,8.00E-18,Q3T0X9,DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12),DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12),GO:0006260; GO:0003887; GO:0005634; GO:0001938,DNA replication; DNA-directed DNA polymerase activity; nucleus; positive regulation of endothelial cell proliferation,PF04081;,,,,,,,,,DPOD4_BOVIN,Bos taurus (Bovine),DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; positive regulation of endothelial cell proliferation [GO:0001938] comp94441_c0_seq1,280,44.6429,0.36646268,18,3,,4.00E-35,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,1.00E-45,CHOYP_RN213.7.13,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp94460_c1_seq1,234,41.0256,0.41446965,1,18,,3.00E-13,Q8HXX6,Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3),GO:0016787; GO:0005764; GO:0006665,hydrolase activity; lysosome; sphingolipid metabolic process,PF02221;,,,,,,,,,SAP3_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),ganglioside catabolic process [GO:0006689] comp94466_c1_seq1,251,42.6295,0.5454632,5,5,,7.00E-10,Q4R7I4,Spermatogenesis-associated protein 24 (Testis protein T6441 homolog),Spermatogenesis-associated protein 24 (Testis protein T6441 homolog),GO:0003677; GO:0030154; GO:0005737; GO:0007275; GO:0005730; GO:0005654; GO:0006355; GO:0007283; GO:0006351,"DNA binding; cell differentiation; cytoplasm; multicellular organismal development; nucleolus; nucleoplasm; regulation of transcription, DNA-dependent; spermatogenesis; transcription, DNA-dependent",PF15175;,,,,,,,,,SPA24_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),"cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]" comp94469_c0_seq1,329,41.9453,0.84309912,3,18,,7.00E-11,Q60631,Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2),Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2),GO:0008180; GO:0005794; GO:0070436; GO:0007265; GO:0017124; GO:0005070; GO:0007568; GO:0048646; GO:0060670; GO:0030154; GO:0071479; GO:0005829; GO:0005768; GO:0008286; GO:0005886; GO:0030838; GO:2000379; GO:0051291; GO:0031623; GO:0043408; GO:0042770; GO:0012506,COP9 signalosome; Golgi apparatus; Grb2-EGFR complex; Ras protein signal transduction; SH3 domain binding; SH3/SH2 adaptor activity; aging; anatomical structure formation involved in morphogenesis; branching involved in labyrinthine layer morphogenesis; cell differentiation; cellular response to ionizing radiation; cytosol; endosome; insulin receptor signaling pathway; plasma membrane; positive regulation of actin filament polymerization; positive regulation of reactive oxygen species metabolic process; protein heterooligomerization; receptor internalization; regulation of MAPK cascade; signal transduction in response to DNA damage; vesicle membrane,PF00017;PF00018;,2.00E-13,CHOYP_BRAFLDRAFT_91062.1.1,,,,,,,GRB2_MOUSE,Mus musculus (Mouse),aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell differentiation [GO:0030154]; cellular response to ionizing radiation [GO:0071479]; Fc-epsilon receptor signaling pathway [GO:0038095]; insulin receptor signaling pathway [GO:0008286]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770] comp94481_c0_seq1,467,46.2527,0.36123665,18,48,,6.00E-31,Q8VE19,WD repeat-containing protein mio,WD repeat-containing protein mio,,,PF17034;,,,,,,,,,MIO_MOUSE,Mus musculus (Mouse),cellular protein complex localization [GO:0034629]; cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008] comp94482_c0_seq1,533,44.8405,0.49942622,21,24,,7.00E-28,P90648,Myosin heavy chain kinase B (MHCK-B) (EC 2.7.11.7),Myosin heavy chain kinase B (MHCK-B) (EC 2.7.11.7),GO:0005524; GO:0005826; GO:0000281; GO:0031037; GO:0016905; GO:0018107; GO:0046777,ATP binding; actomyosin contractile ring; mitotic cytokinesis; myosin II filament disassembly; myosin heavy chain kinase activity; peptidyl-threonine phosphorylation; protein autophosphorylation,PF02816;PF00400;,,,,,,,,,MHCKB_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; myosin II filament disassembly [GO:0031037]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777] comp94482_c1_seq1,347,49.2795,0.64280159,6,4,,8.00E-19,C5FP68,Probable E3 ubiquitin ligase complex SCF subunit sconB (Sulfur controller B) (Sulfur metabolite repression control protein B),Probable E3 ubiquitin ligase complex SCF subunit sconB (Sulfur controller B) (Sulfur metabolite repression control protein B),GO:0016567; GO:0006355; GO:0006351,"protein ubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF12937;PF00400;,2.00E-26,CHOYP_LOC756678.2.2,,,,,,,SCONB_ARTOC,Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis),"protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp94482_c1_seq2,313,46.6454,0.62737903,2,0,,2.00E-07,O42469,Transducin-like enhancer protein 1 (Enhancer of split groucho-like protein 1) (ESG1),Transducin-like enhancer protein 1 (Enhancer of split groucho-like protein 1) (ESG1),GO:0005634; GO:0006355,"nucleus; regulation of transcription, DNA-dependent",PF03920;PF00400;,,,,,,,,,TLE1_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]" comp94491_c0_seq1,390,71.2821,1.0567637,0,11,,1.00E-32,P57037,Capsule polysaccharide modification protein LipA,Capsule polysaccharide modification protein LipA,GO:0005886; GO:0000271; GO:0015774,plasma membrane; polysaccharide biosynthetic process; polysaccharide transport,PF05159;,,,,,,,,,LIPM_NEIMA,Neisseria meningitidis serogroup A / serotype 4A (strain Z2491),polysaccharide biosynthetic process [GO:0000271]; polysaccharide transport [GO:0015774] comp94519_c0_seq1,363,45.1791,0.27765276,7,20,,7.00E-41,Q9NX74,tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.-) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2),tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.-) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2),GO:0005737; GO:0003725; GO:0005783; GO:0050660; GO:0005739; GO:0060548; GO:0004860; GO:0017150; GO:0002943,cytoplasm; double-stranded RNA binding; endoplasmic reticulum; flavin adenine dinucleotide binding; mitochondrion; negative regulation of cell death; protein kinase inhibitor activity; tRNA dihydrouridine synthase activity; tRNA dihydrouridine synthesis,PF00035;PF01207;,4.00E-41,CHOYP_ARP6.1.1,,,,,,,DUS2L_HUMAN,Homo sapiens (Human),negative regulation of cell death [GO:0060548] comp94539_c1_seq1,228,42.1053,0.70680372,10,8,,2.00E-06,Q7TMF2,3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1),3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1),GO:0008408; GO:0005737; GO:0031047; GO:0071204; GO:0071207; GO:0046872; GO:0005730; GO:0031125; GO:0019843; GO:0043022,3'-5' exonuclease activity; cytoplasm; gene silencing by RNA; histone pre-mRNA 3'end processing complex; histone pre-mRNA stem-loop binding; metal ion binding; nucleolus; rRNA 3'-end processing; rRNA binding; ribosome binding,PF00929;PF02037;,,,,,,,,,ERI1_MOUSE,Mus musculus (Mouse),"exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; gene silencing by RNA [GO:0031047]; rRNA 3'-end processing [GO:0031125]" comp94547_c0_seq1,265,46.7925,0.34608872,1,19,,3.00E-13,O14681,Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein),Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein),GO:0006915; GO:0006914; GO:0005789; GO:0016021; GO:0030308; GO:0031965; GO:0042493,apoptotic process; autophagy; endoplasmic reticulum membrane; integral to membrane; negative regulation of cell growth; nuclear membrane; response to drug,,7.00E-11,CHOYP_EI24.1.1,,,,,,,EI24_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; autophagy [GO:0006914]; negative regulation of cell growth [GO:0030308] comp94549_c0_seq1,343,38.484,0.76125555,0,118,,9.00E-06,Q8IXL6,Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi-enriched fraction casein kinase) (GEF-CK) (Protein FAM20C),Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi casein kinase) (Golgi-enriched fraction casein kinase) (GEF-CK),GO:0005509; GO:0097187; GO:0070166; GO:0005615; GO:0071895; GO:0036179; GO:0030501; GO:0045669; GO:0004674; GO:0040036; GO:0051174; GO:0001501,calcium ion binding; dentinogenesis; enamel mineralization; extracellular space; odontoblast differentiation; osteoclast maturation; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; protein serine/threonine kinase activity; regulation of fibroblast growth factor receptor signaling pathway; regulation of phosphorus metabolic process; skeletal system development,PF06702;,,,,,,,,,DMP4_HUMAN,Homo sapiens (Human),biomineral tissue development [GO:0031214]; dentinogenesis [GO:0097187]; enamel mineralization [GO:0070166]; odontoblast differentiation [GO:0071895]; osteoclast maturation [GO:0036179]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; protein phosphorylation [GO:0006468]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of phosphorus metabolic process [GO:0051174] comp94554_c0_seq1,383,56.1358,1.06390336,2,18,,3.00E-61,Q82K93,DNA translocase FtsK,DNA translocase FtsK,GO:0005524; GO:0003677; GO:0007049; GO:0051301; GO:0007059; GO:0016021; GO:0017111; GO:0005886,ATP binding; DNA binding; cell cycle; cell division; chromosome segregation; integral to membrane; nucleoside-triphosphatase activity; plasma membrane,PF09397;PF01580;,,,,,,,,,FTSK_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059] comp94557_c0_seq1,379,61.4776,0.9478524,1,28,,1.00E-09,O69981,Vitamin B12-dependent ribonucleotide reductase (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase NrdJ),Vitamin B12-dependent ribonucleotide reductase (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase NrdJ),GO:0006260; GO:0031419; GO:0050897; GO:0000166; GO:0004748,"DNA replication; cobalamin binding; cobalt ion binding; nucleotide binding; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",PF08471;PF02867;,,,,,,,,,NRDJ_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),deoxyribonucleotide biosynthetic process [GO:0009263]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260] comp94577_c0_seq1,725,42.069,0.69704244,29,9,,8.00E-30,P55013,Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter),Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter),GO:0015377; GO:0016021; GO:0006813; GO:0006814,cation:chloride symporter activity; integral to membrane; potassium ion transport; sodium ion transport,PF00324;PF08403;PF03522;,1.00E-38,CHOYP_S12A2.1.2,,,,,,,S12A2_SQUAC,Squalus acanthias (Spiny dogfish),potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] comp94584_c0_seq1,3523,32.7562,0.40346488,2980,2472,,4.00E-58,Q9D903,Probable rRNA-processing protein EBP2,Probable rRNA-processing protein EBP2,GO:0007059; GO:0005730; GO:0006364,chromosome segregation; nucleolus; rRNA processing,PF05890;,1.00E-65,CHOYP_LOC100185469.1.2,6.00E-112,ruditapes_c380,1.00E-63,ES789955.p.cg.6,5,,EBP2_MOUSE,Mus musculus (Mouse),ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] comp94589_c0_seq1,399,43.609,0.42480023,14,15,,3.00E-42,Q6AX60,Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog),GO:0034464; GO:0060170; GO:0005737; GO:0005815,BBSome; cilium membrane; cytoplasm; microtubule organizing center,PF14728;PF14727;,3.00E-24,CHOYP_PTHB1.1.1,,,,,,,PTHB1_XENLA,Xenopus laevis (African clawed frog), comp945_c0_seq1,215,41.3953,0.44907416,2,1,,2.00E-10,Q14517,"Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]","Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]",GO:0007015; GO:0009653; GO:0005509; GO:0016477; GO:0016337; GO:0005911; GO:0007267; GO:0007163; GO:0030175; GO:0007156; GO:0005887; GO:0030027; GO:0005634; GO:0048471,actin filament organization; anatomical structure morphogenesis; calcium ion binding; cell migration; cell-cell adhesion; cell-cell junction; cell-cell signaling; establishment or maintenance of cell polarity; filopodium; homophilic cell adhesion; integral to plasma membrane; lamellipodium; nucleus; perinuclear region of cytoplasm,PF00028;PF00008;PF02210;,,,,,,,,,FAT1_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337] comp94630_c0_seq1,227,36.5639,0.276369,4,11,,2.00E-13,Q96DT6,Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (Autophagy-related protein 4 homolog C),Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (Autophagy-related protein 4 homolog C),GO:0000045; GO:0004197; GO:0005829; GO:0005576; GO:0006612; GO:0006508,autophagic vacuole assembly; cysteine-type endopeptidase activity; cytosol; extracellular region; protein targeting to membrane; proteolysis,PF03416;,2.00E-11,CHOYP_ATG4D.1.1,,,,,,,ATG4C_HUMAN,Homo sapiens (Human),autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; C-terminal protein lipidation [GO:0006501]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein delipidation [GO:0051697]; protein processing [GO:0016485]; protein targeting to membrane [GO:0006612]; proteolysis [GO:0006508] comp94664_c0_seq1,370,48.3784,0.78936747,10,14,,2.00E-41,Q64143,Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK),GO:0005942; GO:0035014; GO:0043551,phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase regulator activity; regulation of phosphatidylinositol 3-kinase activity,PF16454;PF00017;,1.00E-23,CHOYP_LOC100372481.1.1,,,,,,,P55G_MOUSE,Mus musculus (Mouse),insulin receptor signaling pathway [GO:0008286]; positive regulation of glucose import in response to insulin stimulus [GO:2001275] comp94671_c0_seq1,351,46.7236,0.61227568,7,4,,3.00E-19,A6H603,NACHT and WD repeat domain-containing protein 1,NACHT domain- and WD repeat-containing protein 1,GO:0005524,ATP binding,PF12894;PF00400;,1.00E-28,CHOYP_LOC100366460.1.2,,,,,,,NWD1_MOUSE,Mus musculus (Mouse), comp94682_c0_seq1,250,41.2,0.66252945,0,16,,2.00E-10,A1A4M6,StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5),StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5),GO:0008289; GO:0006869,lipid binding; lipid transport,PF01852;,,,,,,,,,STAR5_BOVIN,Bos taurus (Bovine),lipid transport [GO:0006869] comp94694_c1_seq1,330,43.6364,0.51090571,5,4,,2.00E-35,Q6P6Y1,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,LisH domain and HEAT repeat-containing protein KIAA1468 homolog,,,,,,,,,,,,K1468_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp9469_c0_seq1,202,37.1287,1.21742114,3,0,,4.00E-06,A4D1F6,Leucine-rich repeat and death domain-containing protein 1,Leucine-rich repeat and death domain-containing protein 1,GO:0007165,signal transduction,PF00560;PF13855;,,,,,,,,,LRRD1_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165] comp94709_c1_seq1,218,31.6514,0.55304194,4,7,,,,,,,,,,,4.00E-17,ruditapes_c30953,,,,,,, comp94714_c0_seq1,772,34.0674,0.67570043,1605,36,,5.00E-11,A8SMG2,Uncharacterized protein C5orf48 homolog,Testis-expressed sequence 43 protein,,,PF14983;,4.00E-32,CHOYP_LOC754355.1.1,5.00E-74,ruditapes_c16536,,,,,CE048_BOVIN,Bos taurus (Bovine), comp94718_c0_seq1,305,47.8689,1.02001096,4,2,,1.00E-25,Q27640,Aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase [NAD(+)]),Aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase [NAD(+)]),GO:0004029; GO:0006068,aldehyde dehydrogenase (NAD) activity; ethanol catabolic process,PF00171;,,,2.00E-28,ruditapes_c3450,,,,,ALDH_ENCBU,Enchytraeus buchholzi (Grindal worm),ethanol catabolic process [GO:0006068] comp94722_c0_seq1,785,46.1146,0.55492533,7,9,,1.00E-61,Q5G267,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_MACMU,Macaca mulatta (Rhesus macaque),exocytosis [GO:0006887] comp94722_c0_seq2,544,47.4265,0.55836777,0,0,,1.00E-33,Q4A3R3,Deleted in malignant brain tumors 1 protein (Hensin),Deleted in malignant brain tumors 1 protein (Hensin),GO:0030154; GO:0005576; GO:0019898; GO:0016021; GO:0007275; GO:0015031; GO:0005044; GO:0030658; GO:0035375; GO:0042589,cell differentiation; extracellular region; extrinsic to membrane; integral to membrane; multicellular organismal development; protein transport; scavenger receptor activity; transport vesicle membrane; zymogen binding; zymogen granule membrane,PF00431;PF00530;PF00100;,,,,,,,,,DMBT1_PIG,Sus scrofa (Pig),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein transport [GO:0015031] comp94728_c1_seq1,298,41.9463,0.38274881,3,30,,2.00E-07,Q9P2N2,Rho GTPase-activating protein 28 (Rho-type GTPase-activating protein 28),Rho GTPase-activating protein 28 (Rho-type GTPase-activating protein 28),GO:0005096; GO:0005829; GO:0005634; GO:0043547; GO:0051056; GO:0007264,GTPase activator activity; cytosol; nucleus; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00620;,,,,,,,,,RHG28_HUMAN,Homo sapiens (Human),regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp94766_c0_seq1,419,43.1981,1.10944028,9,31,,1.00E-06,Q5G265,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_SAGLB,Saguinus labiatus (Red-chested mustached tamarin),exocytosis [GO:0006887] comp94768_c0_seq1,546,35.7143,1.15158281,12,27,,7.00E-44,Q14549,Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1),Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1),GO:0000228; GO:0043565; GO:0003700; GO:0006351,"nuclear chromosome; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00046;,,,,,,,,,GBX1_HUMAN,Homo sapiens (Human),"adult walking behavior [GO:0007628]; neuron fate commitment [GO:0048663]; proprioception [GO:0019230]; regulation of transcription, DNA-templated [GO:0006355]; sensory neuron axon guidance [GO:0097374]; spinal cord motor neuron differentiation [GO:0021522]; transcription, DNA-templated [GO:0006351]" comp94782_c2_seq1,1129,44.907,0.40825014,39,34,,3.00E-108,Q08462,Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2),Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2),GO:0005524; GO:0007202; GO:0034199; GO:0004016; GO:0008179; GO:0007189; GO:0007193; GO:0008294; GO:0071377; GO:0005737; GO:0030425; GO:0006112; GO:0007173; GO:0008543; GO:0045087; GO:0016021; GO:0035556; GO:0045121; GO:0046872; GO:0048011; GO:0005886; GO:0043234; GO:0046982; GO:0007268; GO:0055085; GO:0006833,ATP binding; activation of phospholipase C activity; activation of protein kinase A activity; adenylate cyclase activity; adenylate cyclase binding; adenylate cyclase-activating G-protein coupled receptor signaling pathway; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; calcium- and calmodulin-responsive adenylate cyclase activity; cellular response to glucagon stimulus; cytoplasm; dendrite; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; integral to membrane; intracellular signal transduction; membrane raft; metal ion binding; neurotrophin TRK receptor signaling pathway; plasma membrane; protein complex; protein heterodimerization activity; synaptic transmission; transmembrane transport; water transport,PF16214;PF06327;PF00211;,8.00E-88,CHOYP_APLB.1.1,,,,,,,ADCY2_HUMAN,Homo sapiens (Human),activation of adenylate cyclase activity [GO:0007190]; activation of protein kinase A activity [GO:0034199]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to forskolin [GO:1904322]; cellular response to glucagon stimulus [GO:0071377]; renal water homeostasis [GO:0003091] comp94783_c0_seq1,291,58.7629,1.16512108,0,19,,3.00E-10,A7MKD6,K(+)/H(+) antiporter NhaP2 (Potassium/proton antiporter NhaP2),K(+)/H(+) antiporter NhaP2 (Potassium/proton antiporter NhaP2),GO:0050660; GO:0005887; GO:0016614; GO:0015459; GO:0015386; GO:0043266,"flavin adenine dinucleotide binding; integral to plasma membrane; oxidoreductase activity, acting on CH-OH group of donors; potassium channel regulator activity; potassium:hydrogen antiporter activity; regulation of potassium ion transport",PF03471;PF00999;PF02080;,,,,,,,,,CVRA_CROS8,Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii),cell volume homeostasis [GO:0006884]; regulation of potassium ion transport [GO:0043266] comp94789_c0_seq1,281,39.5018,1.19027481,14,0,,3.00E-07,Q8WXQ8,Carboxypeptidase A5 (EC 3.4.17.1),Carboxypeptidase A5 (EC 3.4.17.-),GO:0005576; GO:0004181; GO:0006508; GO:0008270,extracellular region; metallocarboxypeptidase activity; proteolysis; zinc ion binding,PF00246;PF02244;,,,,,,,,,CBPA5_HUMAN,Homo sapiens (Human), comp94791_c1_seq1,247,55.4656,1.27018727,0,15,,7.00E-51,Q6A5D0,Uronate isomerase (EC 5.3.1.12) (Glucuronate isomerase) (Uronic isomerase),Uronate isomerase (EC 5.3.1.12) (Glucuronate isomerase) (Uronic isomerase),GO:0006064; GO:0008880,glucuronate catabolic process; glucuronate isomerase activity,PF02614;,,,,,,,,,UXAC_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),glucuronate catabolic process [GO:0006064] comp94822_c0_seq1,207,42.9952,0.10537227,6,5,,2.00E-22,Q9EQH3,Vacuolar protein sorting-associated protein 35 (Maternal-embryonic 3) (Vesicle protein sorting 35),Vacuolar protein sorting-associated protein 35 (Maternal-embryonic 3) (Vesicle protein sorting 35),GO:0005829; GO:0005768; GO:0016021; GO:0015031; GO:0006624,cytosol; endosome; integral to membrane; protein transport; vacuolar protein processing,PF03635;,1.00E-45,CHOYP_VPS35.1.1,,,,,,,VPS35_MOUSE,Mus musculus (Mouse),"intracellular protein transport [GO:0006886]; negative regulation of late endosome to lysosome transport [GO:1902823]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt protein secretion [GO:0061357]; regulation of protein stability [GO:0031647]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; transcytosis [GO:0045056]; vacuolar protein processing [GO:0006624]" comp94825_c0_seq1,615,34.4715,0.93877433,15,27,,,,,,,,,,,2.00E-110,ruditapes_c23147,,,,,,, comp94839_c0_seq1,206,29.6117,0.22549551,11,0,,,,,,,,,6.00E-11,CHOYP_LOC100893397.1.2,2.00E-13,ruditapes_c16815,,,,,,, comp94842_c0_seq1,283,45.2297,0.97452197,1,20,,3.00E-21,A8Y236,Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10),Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10),GO:0000139; GO:0016021; GO:0046872; GO:0004653; GO:0006486,Golgi membrane; integral to membrane; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,,,,,,,,,GLT10_CAEBR,Caenorhabditis briggsae,protein glycosylation [GO:0006486] comp94856_c0_seq1,303,40.264,0.73529422,4,0,,1.00E-10,Q9TU53,Cubilin,Cubilin,GO:0005509; GO:0008203; GO:0031419; GO:0010008; GO:0005765; GO:0015031,calcium ion binding; cholesterol metabolic process; cobalamin binding; endosome membrane; lysosomal membrane; protein transport,PF00431;PF00008;PF12947;PF07645;,,,,,,,,,CUBN_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] comp94872_c0_seq1,221,32.5792,0,0,12,,2.00E-08,Q05096,Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1),Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1),GO:0005524; GO:0003779; GO:0051017; GO:0030048; GO:0030898; GO:0005903; GO:0005516; GO:0005737; GO:0005856; GO:0030175; GO:0000146; GO:0016459; GO:0007399; GO:0005547; GO:0005546; GO:0005886,"ATP binding; actin binding; actin filament bundle assembly; actin filament-based movement; actin-dependent ATPase activity; brush border; calmodulin binding; cytoplasm; cytoskeleton; filopodium; microfilament motor activity; myosin complex; nervous system development; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; plasma membrane",PF00612;PF00063;PF06017;,1.00E-14,CHOYP_MYO1B.1.1,,,,,,,MYO1B_RAT,Rattus norvegicus (Rat),actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892] comp94873_c1_seq1,254,44.0945,0.24402292,5,9,,3.00E-20,Q9C0C7,Activating molecule in BECN1-regulated autophagy protein 1,Activating molecule in BECN1-regulated autophagy protein 1,GO:0005776; GO:0006914; GO:0030154; GO:0005737; GO:0031410; GO:0008285; GO:0021915; GO:0043065,autophagic vacuole; autophagy; cell differentiation; cytoplasm; cytoplasmic vesicle; negative regulation of cell proliferation; neural tube development; positive regulation of apoptotic process,,1.00E-26,CHOYP_BRAFLDRAFT_126632.1.1,,,,,,,AMRA1_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; parkin-mediated mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of mitophagy [GO:1903599]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of autophagosome assembly [GO:2000785] comp94886_c0_seq2,310,43.5484,0.20669245,6,7,,4.00E-08,O00750,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta),Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta),GO:0016303; GO:0035005; GO:0005524; GO:0030139; GO:0005783; GO:0043231; GO:0001727; GO:0005634; GO:0005942; GO:0035091; GO:0048015; GO:0005886; GO:0043491; GO:0044281,1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; endocytic vesicle; endoplasmic reticulum; intracellular membrane-bounded organelle; lipid kinase activity; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol binding; phosphatidylinositol-mediated signaling; plasma membrane; protein kinase B signaling cascade; small molecule metabolic process,PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;,,,,,,,,,P3C2B_HUMAN,Homo sapiens (Human),phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491] comp94892_c0_seq1,939,42.279,0.69378069,24,34,,2.00E-26,Q4VSN1,Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5),GO:0005524; GO:0005737; GO:0018108; GO:0004674; GO:0004712; GO:0004713,ATP binding; cytoplasm; peptidyl-tyrosine phosphorylation; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity,PF00069;,1.00E-21,CHOYP_NEMVEDRAFT_V1G241055.1.1,,,,,,,DUSTY_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),embryonic organ development [GO:0048568]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] comp94899_c0_seq1,386,32.9016,0.38393115,9,6,,,,,,,,,6.00E-14,CHOYP_LOC100562878.2.2,,,,,,,,, comp94902_c0_seq1,679,47.8645,0.56938542,35,14,,1.00E-58,Q7TS68,Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6),Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6),GO:0003723; GO:0008168,RNA binding; methyltransferase activity,PF01189;,,,,,,,,,NSUN6_MOUSE,Mus musculus (Mouse),RNA methylation [GO:0001510] comp94934_c0_seq1,241,46.0581,0.95214754,0,239,,,,,,,,,8.00E-48,CHOYP_ARALYDRAFT_497139.1.1,,,,,,,,, comp94935_c0_seq1,245,44.0816,0.34322162,3,17,,2.00E-16,Q0UQV6,GPI inositol-deacylase (EC 3.1.-.-),GPI inositol-deacylase (EC 3.1.-.-),GO:0006505; GO:0005789; GO:0016788; GO:0016021; GO:0006886,"GPI anchor metabolic process; endoplasmic reticulum membrane; hydrolase activity, acting on ester bonds; integral to membrane; intracellular protein transport",PF07819;,,,,,,,,,BST1_PHANO,Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum),protein transport [GO:0015031] comp94935_c1_seq1,318,41.8239,0.4334282,7,2,,2.00E-31,Q3UUQ7,GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1),GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1),GO:0006506; GO:0009948; GO:0009880; GO:0005783; GO:0005789; GO:0021871; GO:0060322; GO:0016021; GO:0006886; GO:0015798; GO:0004518; GO:0042578; GO:0007605,GPI anchor biosynthetic process; anterior/posterior axis specification; embryonic pattern specification; endoplasmic reticulum; endoplasmic reticulum membrane; forebrain regionalization; head development; integral to membrane; intracellular protein transport; myo-inositol transport; nuclease activity; phosphoric ester hydrolase activity; sensory perception of sound,PF07819;,3.00E-16,CHOYP_BRAFLDRAFT_279100.1.1,,,,,,,PGAP1_MOUSE,Mus musculus (Mouse),anterior/posterior axis specification [GO:0009948]; embryonic pattern specification [GO:0009880]; forebrain regionalization [GO:0021871]; GPI anchor biosynthetic process [GO:0006506]; head development [GO:0060322]; myo-inositol transport [GO:0015798]; protein transport [GO:0015031]; sensory perception of sound [GO:0007605] comp94937_c1_seq1,292,48.6301,0.63133686,6,0,,7.00E-17,F7J220,Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1),GO:0030659; GO:0045087; GO:0016021; GO:0006909; GO:0005044,cytoplasmic vesicle membrane; innate immune response; integral to membrane; phagocytosis; scavenger receptor activity,PF00530;PF00084;,,,,,,,,,SRCR1_ASTPE,Patiria pectinifera (Starfish) (Asterina pectinifera),innate immune response [GO:0045087]; phagocytosis [GO:0006909] comp94948_c0_seq1,246,48.374,1.0218845,10,0,,1.00E-12,Q922P8,Transmembrane protein 132A (HSPA5-binding protein 1),Transmembrane protein 132A (HSPA5-binding protein 1),GO:0000139; GO:0005789; GO:0016021,Golgi membrane; endoplasmic reticulum membrane; integral to membrane,PF16070;PF15706;PF15705;,,,,,,,,,T132A_MOUSE,Mus musculus (Mouse), comp9494_c0_seq1,225,44.8889,0.35731931,4,0,,9.00E-19,Q9Y4D2,Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator),GO:0019369; GO:0008219; GO:0046340; GO:0071926; GO:0016021; GO:0046872; GO:0007405; GO:0042136; GO:0005886; GO:0030168; GO:0004806,arachidonic acid metabolic process; cell death; diacylglycerol catabolic process; endocannabinoid signaling pathway; integral to membrane; metal ion binding; neuroblast proliferation; neurotransmitter biosynthetic process; plasma membrane; platelet activation; triglyceride lipase activity,PF01764;,,,,,,,,,DGLA_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136] comp94963_c0_seq1,435,44.1379,0.3063248,13,5,,1.00E-29,Q8BX80,Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96),Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96),GO:0005829; GO:0033925,cytosol; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity,PF03644;,,,,,,,,,ENASE_MOUSE,Mus musculus (Mouse),metabolic process [GO:0008152] comp94963_c1_seq1,207,40.5797,0.7824634,3,0,,,,,,,,,3.00E-15,CHOYP_ENGASE.1.1,,,,,,,,, comp94973_c0_seq1,264,45.0758,0.37557228,4,5,,1.00E-06,Q9HU55,Glutaredoxin,Glutaredoxin,GO:0045454; GO:0005737; GO:0009055; GO:0006091; GO:0009117; GO:0015035,cell redox homeostasis; cytoplasm; electron carrier activity; generation of precursor metabolites and energy; nucleotide metabolic process; protein disulfide oxidoreductase activity,PF00462;,,,,,,,,,GLRX_PSEAE,Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1),cell redox homeostasis [GO:0045454] comp95005_c0_seq1,419,40.8115,0.23077055,4,4,,8.00E-06,P81397,Snaclec rhodocetin subunit alpha,Snaclec rhodocetin subunit alpha,GO:0030246; GO:0005576,carbohydrate binding; extracellular region,PF00059;,,,,,,,,,RHCA_CALRH,Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma), comp95006_c1_seq1,261,44.8276,1.07567561,5,0,,8.00E-06,O42410,DNA-binding protein Ikaros (Ikaros family zinc finger protein 1),DNA-binding protein Ikaros (Ikaros family zinc finger protein 1),GO:0016049; GO:0007204; GO:0002377; GO:0046872; GO:0007275; GO:0045892; GO:0005634; GO:0032993; GO:0000975; GO:0006351,"cell growth; elevation of cytosolic calcium ion concentration; immunoglobulin production; metal ion binding; multicellular organismal development; negative regulation of transcription, DNA-dependent; nucleus; protein-DNA complex; regulatory region DNA binding; transcription, DNA-dependent",PF00096;,,,,,,,,,IKZF1_CHICK,Gallus gallus (Chicken),"cell growth [GO:0016049]; immunoglobulin production [GO:0002377]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp95014_c1_seq1,213,53.5211,0.46121706,5,2,,,,,,,,,5.00E-24,CHOYP_DNAH5.2.2,,,,,,,,, comp95031_c0_seq1,1060,43.8679,0.88328417,3300,50,,6.00E-13,Q5XHX8,Testicular haploid expressed gene protein,Testicular haploid expressed gene protein,GO:0030154; GO:0007275; GO:0005634; GO:0007283,cell differentiation; multicellular organismal development; nucleus; spermatogenesis,PF14912;,4.00E-15,CHOYP_BRAFLDRAFT_120588.1.1,,,,,,,THEG_RAT,Rattus norvegicus (Rat),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283] comp95040_c0_seq2,239,49.7908,0.80001401,9,6,,,,,,,,,,,4.00E-30,ruditapes2_c1368,,,,,,, comp95061_c0_seq1,281,48.7544,0.96164901,3,0,,5.00E-41,Q9Y106,Protein mab-21-like,Protein mab-21-like,GO:0045165,cell fate commitment,PF03281;,,,,,,,,,MB21L_DROME,Drosophila melanogaster (Fruit fly), comp95061_c1_seq1,292,43.4932,0.73031764,4,0,,2.00E-44,Q9Y586,Protein mab-21-like 2,Protein mab-21-like 2,GO:0043010; GO:0010172; GO:0048568; GO:0007399; GO:0005634; GO:0008284,camera-type eye development; embryonic body morphogenesis; embryonic organ development; nervous system development; nucleus; positive regulation of cell proliferation,PF03281;,3.00E-47,CHOYP_LOC661084.1.1,,,,,,,MB212_HUMAN,Homo sapiens (Human),camera-type eye development [GO:0043010]; embryonic body morphogenesis [GO:0010172]; eye development [GO:0001654]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284] comp95069_c0_seq1,1013,47.6802,0.44123833,33,32,,8.00E-15,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp95070_c0_seq1,283,62.1908,1.02700495,0,18,,1.00E-06,Q6D439,UPF0434 protein ECA2555,UPF0434 protein ECA2555,,,PF03966;,,,,,,,,,Y2555_ERWCT,Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica), comp95093_c0_seq1,253,42.2925,0.79875462,3,0,,1.00E-40,A2A891,Calmodulin-binding transcription activator 1,Calmodulin-binding transcription activator 1,GO:0003677; GO:0005737; GO:0005634; GO:0006355; GO:0006351,"DNA binding; cytoplasm; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF03859;PF01833;,,,,,,,,,CMTA1_MOUSE,Mus musculus (Mouse),neuromuscular process controlling balance [GO:0050885]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944] comp95095_c1_seq1,798,42.6065,0.44236894,25,22,,,,,,,,,3.00E-60,CHOYP_LOC100141576.1.1,,,,,,,,, comp95174_c0_seq1,903,41.196,0.96684611,33,0,,1.00E-14,Q3UU35,Ovostatin homolog,Ovostatin homolog,GO:0005615; GO:0010951; GO:0004867,extracellular space; negative regulation of endopeptidase activity; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,OVOS_MOUSE,Mus musculus (Mouse), comp95174_c1_seq1,345,46.087,0.91053397,6,0,,3.00E-18,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,,,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp95174_c2_seq2,263,42.5856,1.09580128,6,0,,7.00E-06,P98093,Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] (Fragment),Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] (Fragment),GO:0006957; GO:0006958; GO:0004866; GO:0005615; GO:0006954; GO:0010951,"complement activation, alternative pathway; complement activation, classical pathway; endopeptidase inhibitor activity; extracellular space; inflammatory response; negative regulation of endopeptidase activity",PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;,,,,,,,,,CO3_ONCMY,Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri),"complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]" comp95183_c0_seq1,247,46.1538,0.45926679,6,8,,5.00E-13,Q96EP0,E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (Zinc in-between-RING-finger ubiquitin-associated domain protein),E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (Zinc in-between-RING-finger ubiquitin-associated domain protein),GO:0035631; GO:0023035; GO:0071797; GO:0050852; GO:0005737; GO:0009898; GO:0043123; GO:0051092; GO:0097039; GO:0043130; GO:0004842; GO:0008270,CD40 receptor complex; CD40 signaling pathway; LUBAC complex; T cell receptor signaling pathway; cytoplasm; internal side of plasma membrane; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; protein linear polyubiquitination; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding,PF16678;PF01485;PF09409;,7.00E-11,CHOYP_LOC100375820.1.1,,,,,,,RNF31_HUMAN,Homo sapiens (Human),CD40 signaling pathway [GO:0023035]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; T cell receptor signaling pathway [GO:0050852] comp95187_c0_seq1,287,44.2509,0.85715326,5,5,,,,,,,,,2.00E-24,CHOYP_BRAFLDRAFT_63883.1.1,,,,,,,,, comp95198_c1_seq1,486,43.0041,0.75815339,7,20,,8.00E-29,P79098,Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13),GO:0004177; GO:0001525; GO:0030154; GO:0016021; GO:0008237; GO:0006508; GO:0009615; GO:0001618; GO:0008270,aminopeptidase activity; angiogenesis; cell differentiation; integral to membrane; metallopeptidase activity; proteolysis; response to virus; virus receptor activity; zinc ion binding,PF11838;PF01433;,,,,,,,,,AMPN_BOVIN,Bos taurus (Bovine),angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] comp95219_c1_seq1,1930,47.1503,0.59861774,76,49,,0,Q60949,TBC1 domain family member 1,TBC1 domain family member 1,GO:0005097; GO:0005829; GO:0005634; GO:0032851,Rab GTPase activator activity; cytosol; nucleus; positive regulation of Rab GTPase activity,PF11830;PF00640;PF00566;,1.00E-125,CHOYP_TBCD4.1.1,2.00E-33,ruditapes_c19862,,,,,TBCD1_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338] comp95222_c1_seq1,203,48.7685,0.3347087,9,7,,3.00E-17,A6QLT2,Myotubularin-related protein 2 (EC 3.1.3.-),"Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)",GO:0031901; GO:0005634; GO:0035335; GO:0004725,early endosome membrane; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF02893;PF06602;,,,,,,,,,MTMR2_BOVIN,Bos taurus (Bovine),phosphatidylinositol dephosphorylation [GO:0046856] comp95232_c1_seq1,413,42.615,0.55533525,8,25,,,,,,,,,3.00E-44,CHOYP_NEMVEDRAFT_V1G232111.1.1,,,,,,,,, comp95234_c1_seq1,323,45.2012,0.42954957,12,10,,4.00E-19,Q9H0J9,Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1),GO:0003950; GO:0046872; GO:0005634,NAD+ ADP-ribosyltransferase activity; metal ion binding; nucleus,PF00644;PF02825;PF00642;,,,,,,,,,PAR12_HUMAN,Homo sapiens (Human), comp95238_c0_seq1,859,38.6496,0.21866289,33,16,,9.00E-39,Q1LWH4,Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15),Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15),GO:0008409; GO:0017108; GO:0000724; GO:0046872; GO:0033683; GO:0005634; GO:0004528; GO:0043130,"5'-3' exonuclease activity; 5'-flap endonuclease activity; double-strand break repair via homologous recombination; metal ion binding; nucleotide-excision repair, DNA incision; nucleus; phosphodiesterase I activity; ubiquitin binding",PF08774;,,,,,,,,,FAN1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]" comp95242_c0_seq1,218,38.5321,0.62217218,3,9,,7.00E-15,Q5ZIB9,Protein arginine N-methyltransferase 7 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT7) (EC 2.1.1.125) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) (EC 2.1.1.126),Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7),GO:0043046; GO:0016277; GO:0030154; GO:0005829; GO:0044020; GO:0005634; GO:0035241; GO:0035243; GO:0006349; GO:0006355; GO:0000387; GO:0006351,"DNA methylation involved in gamete generation; [myelin basic protein]-arginine N-methyltransferase activity; cell differentiation; cytosol; histone methyltransferase activity (H4-R3 specific); nucleus; protein-arginine omega-N monomethyltransferase activity; protein-arginine omega-N symmetric methyltransferase activity; regulation of gene expression by genetic imprinting; regulation of transcription, DNA-dependent; spliceosomal snRNP assembly; transcription, DNA-dependent",,3.00E-14,CHOYP_LOC100867962.1.1,,,,,,,ANM7_CHICK,Gallus gallus (Chicken),"cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; histone arginine methylation [GO:0034969]; histone methylation [GO:0016571]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]; transcription, DNA-templated [GO:0006351]" comp95244_c1_seq1,667,45.1274,0.8067651,9,20,,4.00E-64,Q4KLT0,Probable E3 ubiquitin-protein ligase RNF217 (EC 6.3.2.-) (RING finger protein 217),Probable E3 ubiquitin-protein ligase RNF217 (EC 6.3.2.-) (RING finger protein 217),GO:0016021; GO:0016874; GO:0016567; GO:0008270,integral to membrane; ligase activity; protein ubiquitination; zinc ion binding,PF01485;,,,,,,,,,RN217_XENLA,Xenopus laevis (African clawed frog), comp95245_c0_seq2,429,46.1538,0.48265568,11,0,,2.00E-38,Q32NR9,WD repeat-containing and planar cell polarity effector protein fritz homolog (WD repeat-containing and planar cell polarity effector protein),WD repeat-containing and planar cell polarity effector protein fritz homolog (WD repeat-containing and planar cell polarity effector protein),GO:0035085; GO:0060271; GO:0005856; GO:0060031; GO:0005886; GO:0016476; GO:0032880; GO:0032185,cilium axoneme; cilium morphogenesis; cytoskeleton; mediolateral intercalation; plasma membrane; regulation of embryonic cell shape; regulation of protein localization; septin cytoskeleton organization,PF11768;,2.00E-46,CHOYP_FRITZ.1.1,,,,,,,FRITZ_XENLA,Xenopus laevis (African clawed frog),cilium morphogenesis [GO:0060271]; mediolateral intercalation [GO:0060031]; regulation of embryonic cell shape [GO:0016476]; regulation of protein localization [GO:0032880]; septin cytoskeleton organization [GO:0032185] comp95257_c0_seq1,577,39.8614,0.34964188,19,15,,5.00E-35,Q8C6G8,WD repeat-containing protein 26,WD repeat-containing protein 26,GO:0005737,cytoplasm,PF00400;,1.00E-38,CHOYP_WDR26.1.1,,,,,,,WDR26_MOUSE,Mus musculus (Mouse), comp95276_c1_seq1,345,41.7391,0.3402861,8,27,,1.00E-21,Q54JL3,Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)],Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)],GO:0005794; GO:0005542; GO:0030412; GO:0030409; GO:0019556; GO:0019557; GO:0035999,Golgi apparatus; folic acid binding; formimidoyltetrahydrofolate cyclodeaminase activity; glutamate formimidoyltransferase activity; histidine catabolic process to glutamate and formamide; histidine catabolic process to glutamate and formate; tetrahydrofolate interconversion,PF02971;PF04961;PF07837;,2.00E-20,CHOYP_BRAFLDRAFT_125780.1.1,,,,,,,FTCD_DICDI,Dictyostelium discoideum (Slime mold),histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999] comp95281_c0_seq1,213,46.0094,1.15870942,3,16,,1.00E-15,Q8TAV3,Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1),Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1),GO:0005789; GO:0020037; GO:0005506; GO:0004497; GO:0016705; GO:0044281; GO:0006805,"endoplasmic reticulum membrane; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; small molecule metabolic process; xenobiotic metabolic process",PF00067;,,,,,,,,,CP2W1_HUMAN,Homo sapiens (Human),aflatoxin B1 metabolic process [GO:0043390]; xenobiotic metabolic process [GO:0006805] comp95306_c0_seq1,332,37.9518,1.17936815,2,8,,5.00E-08,Q8MJ08,Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor),Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor),GO:0007188; GO:0016021; GO:2000420; GO:0050728; GO:0033624; GO:0005886; GO:0004957,adenylate cyclase-modulating G-protein coupled receptor signaling pathway; integral to membrane; negative regulation of eosinophil extravasation; negative regulation of inflammatory response; negative regulation of integrin activation; plasma membrane; prostaglandin E receptor activity,PF00001;,,,,,,,,,PE2R4_BOVIN,Bos taurus (Bovine),adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cellular response to prostaglandin E stimulus [GO:0071380]; inflammatory response [GO:0006954]; negative regulation of eosinophil extravasation [GO:2000420]; negative regulation of inflammatory response [GO:0050728]; negative regulation of integrin activation [GO:0033624]; positive regulation of cytosolic calcium ion concentration [GO:0007204] comp95317_c0_seq1,285,45.9649,0.53483594,2,28,,9.00E-29,P08842,Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase),GO:0005794; GO:0005788; GO:0005789; GO:0005768; GO:0008544; GO:0007565; GO:0006687; GO:0016021; GO:0005764; GO:0046872; GO:0005886; GO:0043687; GO:0044281; GO:0006706; GO:0004773,Golgi apparatus; endoplasmic reticulum lumen; endoplasmic reticulum membrane; endosome; epidermis development; female pregnancy; glycosphingolipid metabolic process; integral to membrane; lysosome; metal ion binding; plasma membrane; post-translational protein modification; small molecule metabolic process; steroid catabolic process; steryl-sulfatase activity,PF00884;,,,,,,,,,STS_HUMAN,Homo sapiens (Human),epidermis development [GO:0008544]; female pregnancy [GO:0007565]; glycosphingolipid metabolic process [GO:0006687]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; response to estrogen [GO:0043627]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid catabolic process [GO:0006706] comp95328_c1_seq1,260,40.3846,0.73551813,2,19,,5.00E-31,Q70JA7,Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3),Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3),GO:0032580; GO:0000139; GO:0050510; GO:0005975; GO:0030206; GO:0047238; GO:0016021; GO:0046872,Golgi cisterna membrane; Golgi membrane; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; integral to membrane; metal ion binding,PF05679;,,,,,,,,,CHSS3_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206] comp9533_c0_seq1,264,46.5909,0.49441008,4,5,,,,,,,,,6.00E-12,CHOYP_BRAFLDRAFT_268591.1.1,,,,,,,,, comp95350_c1_seq1,386,45.8549,0.54858616,6,14,,2.00E-23,Q1HCL7,"NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)","NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)",GO:0005524; GO:0019674; GO:0003951; GO:0006741; GO:0005739; GO:0042803,ATP binding; NAD metabolic process; NAD+ kinase activity; NADP biosynthetic process; mitochondrion; protein homodimerization activity,PF01513;,1.00E-22,CHOYP_LOC100902912.1.1,,,,,,,NAKD1_RAT,Rattus norvegicus (Rat),NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741] comp95367_c0_seq1,473,43.3404,0.90337739,11,16,,7.00E-21,Q8K0U4,Heat shock 70 kDa protein 12A,Heat shock 70 kDa protein 12A,GO:0005524,ATP binding,,,,,,,,,,HS12A_MOUSE,Mus musculus (Mouse), comp95368_c0_seq1,600,46.1667,0.50135697,14,15,,4.00E-21,Q5T011,Protein SZT2 (Seizure threshold 2 protein homolog),Protein SZT2 (Seizure threshold 2 protein homolog),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_HUMAN,Homo sapiens (Human),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp95368_c1_seq2,477,49.4759,0.5839767,6,10,,3.00E-33,A2A9C3,Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR),GO:0007417; GO:0005777; GO:0043473; GO:0009791,central nervous system development; peroxisome; pigmentation; post-embryonic development,,,,,,,,,,SZT2_MOUSE,Mus musculus (Mouse),central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668] comp95384_c0_seq1,298,34.2282,1.15668614,0,0,,,,,,,,,,,2.00E-72,ruditapes_c10792,,,,,,, comp95392_c1_seq1,201,36.8159,0.30060268,5,0,,4.00E-07,Q924C3,Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)],GO:0035529; GO:0016323; GO:0031214; GO:0005576; GO:0006955; GO:0016021; GO:0046872; GO:0003676; GO:0004528; GO:0005886; GO:0030247; GO:0005044,NADH pyrophosphatase activity; basolateral plasma membrane; biomineral tissue development; extracellular region; immune response; integral to membrane; metal ion binding; nucleic acid binding; phosphodiesterase I activity; plasma membrane; polysaccharide binding; scavenger receptor activity,PF01223;PF01663;PF01033;,,,,,,,,,ENPP1_RAT,Rattus norvegicus (Rat),biomineral tissue development [GO:0031214]; immune response [GO:0006955] comp95402_c0_seq1,392,39.0306,0.56689875,9,18,,,,,,,,,5.00E-21,CHOYP_IFRX2.4.10,,,,,,,,, comp95412_c0_seq1,463,38.6609,0.53008625,7,42,,5.00E-27,Q9CY52,Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase),Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase),GO:0005524; GO:0005525; GO:0005737; GO:0000287; GO:0005739; GO:0051289; GO:0008193; GO:0006400,ATP binding; GTP binding; cytoplasm; magnesium ion binding; mitochondrion; protein homotetramerization; tRNA guanylyltransferase activity; tRNA modification,PF04446;PF14413;,,,,,,,,,THG1_MOUSE,Mus musculus (Mouse),protein homotetramerization [GO:0051289]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] comp95421_c0_seq2,508,38.7795,0.26733297,8,22,,6.00E-09,Q9CL21,ATP-dependent DNA helicase RecQ (EC 3.6.4.12),ATP-dependent DNA helicase RecQ (EC 3.6.4.12),GO:0005524; GO:0043140; GO:0003677; GO:0006310; GO:0006281; GO:0006260; GO:0009432; GO:0005622,ATP binding; ATP-dependent 3'-5' DNA helicase activity; DNA binding; DNA recombination; DNA repair; DNA replication; SOS response; intracellular,PF00270;PF00271;PF00570;PF16124;PF09382;,,,,,,,,,RECQ_PASMU,Pasteurella multocida (strain Pm70),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] comp95460_c0_seq1,397,41.8136,0.23384402,8,0,,4.00E-10,Q62210,Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Inhibitor of apoptosis protein 2) (IAP-2) (mIAP-2) (mIAP2),Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2),GO:0035631; GO:0006915; GO:0005737; GO:0009898; GO:0070266; GO:0060546; GO:1902443; GO:0005634; GO:0001890; GO:0043123; GO:0043161; GO:0070936; GO:0070534; GO:0042981; GO:0051726; GO:2000377; GO:0006355; GO:0003713; GO:0006351; GO:0004842; GO:0008270,"CD40 receptor complex; apoptotic process; cytoplasm; internal side of plasma membrane; necroptosis; negative regulation of necroptosis; negative regulation of ripoptosome assembly involved in necroptosis; nucleus; placenta development; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein K63-linked ubiquitination; regulation of apoptotic process; regulation of cell cycle; regulation of reactive oxygen species metabolic process; regulation of transcription, DNA-dependent; transcription coactivator activity; transcription, DNA-dependent; ubiquitin-protein ligase activity; zinc ion binding",PF00653;PF00619;,,,,,,,,,BIRC2_MOUSE,Mus musculus (Mouse),"inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]" comp95463_c0_seq1,401,38.9027,0.46260357,1,28,,5.00E-07,Q8TBF5,Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X),Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X),GO:0006501; GO:0005789; GO:0016021; GO:0016254,C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane,PF08320;,,,,,,,,,PIGX_HUMAN,Homo sapiens (Human),preassembly of GPI anchor in ER membrane [GO:0016254] comp95472_c0_seq1,305,41.9672,0.55335134,4,28,,7.00E-06,Q8IXQ6,Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein),Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein),GO:0003950; GO:0016477; GO:0005737; GO:0005829; GO:0006302; GO:0005634; GO:0060330,NAD+ ADP-ribosyltransferase activity; cell migration; cytoplasm; cytosol; double-strand break repair; nucleus; regulation of response to interferon-gamma,PF01661;,,,,,,,,,PARP9_HUMAN,Homo sapiens (Human),cell migration [GO:0016477]; double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330] comp95480_c0_seq1,436,42.4312,0.20944275,8,29,,9.00E-47,O00471,Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10),Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10),GO:0044267; GO:0005829; GO:0006887; GO:0006892; GO:0015031; GO:0048278,cellular protein metabolic process; cytosol; exocytosis; post-Golgi vesicle-mediated transport; protein transport; vesicle docking,PF07393;,1.00E-41,CHOYP_BRAFLDRAFT_125658.1.1,,,,,,,EXOC5_HUMAN,Homo sapiens (Human),exocytosis [GO:0006887]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; vesicle docking [GO:0048278] comp95487_c0_seq1,511,47.1624,0.78879854,20,40,,9.00E-09,O75954,Tetraspanin-9 (Tspan-9) (Tetraspan NET-5),Tetraspanin-9 (Tspan-9) (Tetraspan NET-5),GO:0005887,integral to plasma membrane,PF00335;,,,,,,,,,TSN9_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166] comp95488_c2_seq1,368,44.2935,0.56682446,11,18,,1.00E-28,O19094,Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137),Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137),GO:0008458; GO:0006635; GO:0006091; GO:0051791; GO:0005777; GO:0006810,carnitine O-octanoyltransferase activity; fatty acid beta-oxidation; generation of precursor metabolites and energy; medium-chain fatty acid metabolic process; peroxisome; transport,PF00755;,4.00E-22,CHOYP_OCTC.1.1,,,,,,,OCTC_BOVIN,Bos taurus (Bovine),carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; transport [GO:0006810] comp95523_c1_seq1,505,38.4158,1.02571617,8,35,,3.00E-24,Q9HCG1,Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18),Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18),GO:0003677; GO:0030097; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; hemopoiesis; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN160_HUMAN,Homo sapiens (Human),"hemopoiesis [GO:0030097]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp95528_c0_seq1,203,43.3498,0.63355575,1,18,,1.00E-33,P15153,Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2),Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2),GO:0005525; GO:0003924; GO:0030036; GO:0007411; GO:0045453; GO:0030031; GO:0005829; GO:0005635; GO:0005886; GO:0030168; GO:0008284; GO:0010310; GO:0060263; GO:0051056; GO:0007264,GTP binding; GTPase activity; actin cytoskeleton organization; axon guidance; bone resorption; cell projection assembly; cytosol; nuclear envelope; plasma membrane; platelet activation; positive regulation of cell proliferation; regulation of hydrogen peroxide metabolic process; regulation of respiratory burst; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction,PF00071;,2.00E-23,CHOYP_RAC1.2.3,,,,,,,RAC2_HUMAN,Homo sapiens (Human),actin filament organization [GO:0007015]; bone resorption [GO:0045453]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; G-protein coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; platelet activation [GO:0030168]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of cell-substrate adhesion [GO:0010810]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of neutrophil migration [GO:1902622]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] comp95528_c1_seq2,227,46.696,0.33431734,1,0,,6.00E-06,P22279,Ras-like protein 2,Ras-like protein 2,GO:0005525; GO:0003924; GO:0005886; GO:0007264,GTP binding; GTPase activity; plasma membrane; small GTPase mediated signal transduction,PF00071;,4.00E-38,CHOYP_AAEL_AAEL015271.1.1,2.00E-16,ruditapes2_c2197,,,,,RAS2_MUCCL,Mucor circinelloides f. lusitanicus (Mucor racemosus var. lusitanicus),small GTPase mediated signal transduction [GO:0007264] comp95528_c2_seq1,367,37.3297,0.55137396,4,32,,2.00E-17,P80236,Ras-related C3 botulinum toxin substrate 1 (Sigma 1 component protein p22) (p21-Rac1) (Fragment),Ras-related C3 botulinum toxin substrate 1 (Sigma 1 component protein p22) (p21-Rac1) (Fragment),GO:0005525; GO:0006184; GO:0003924; GO:0060071; GO:0048532; GO:0002093; GO:0007411; GO:0048870; GO:0045216; GO:0021799; GO:0090103; GO:0007010; GO:0048813; GO:0071542; GO:0021831; GO:0043652; GO:0003382; GO:0019897; GO:0006972; GO:0030027; GO:0030032; GO:0042470; GO:0001891; GO:0030838; GO:0043552; GO:0001934; GO:0030334; GO:0097178; GO:0032587; GO:0007264; GO:0034446,"GTP binding; GTP catabolic process; GTPase activity; Wnt receptor signaling pathway, planar cell polarity pathway; anatomical structure arrangement; auditory receptor cell morphogenesis; axon guidance; cell motility; cell-cell junction organization; cerebral cortex radially oriented cell migration; cochlea morphogenesis; cytoskeleton organization; dendrite morphogenesis; dopaminergic neuron differentiation; embryonic olfactory bulb interneuron precursor migration; engulfment of apoptotic cell; epithelial cell morphogenesis; extrinsic to plasma membrane; hyperosmotic response; lamellipodium; lamellipodium assembly; melanosome; phagocytic cup; positive regulation of actin filament polymerization; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of protein phosphorylation; regulation of cell migration; ruffle assembly; ruffle membrane; small GTPase mediated signal transduction; substrate adhesion-dependent cell spreading",PF00071;,,,,,,,,,RAC1_CAVPO,Cavia porcellus (Guinea pig),cell motility [GO:0048870]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell migration [GO:0030334]; small GTPase mediated signal transduction [GO:0007264] comp95531_c0_seq1,1249,40.5925,0.29301472,17,8,,4.00E-21,Q8TDI7,Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2),Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2),GO:0050910; GO:0016021; GO:0006811; GO:0032426; GO:0060005,detection of mechanical stimulus involved in sensory perception of sound; integral to membrane; ion transport; stereocilium bundle tip; vestibular reflex,PF07810;,,,,,,,,,TMC2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; vestibular reflex [GO:0060005] comp95531_c0_seq2,1206,40.5473,0.30378557,2,0,,1.00E-06,Q8TDI7,Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2),Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2),GO:0050910; GO:0016021; GO:0006811; GO:0032426; GO:0060005,detection of mechanical stimulus involved in sensory perception of sound; integral to membrane; ion transport; stereocilium bundle tip; vestibular reflex,PF07810;,,,,,,,,,TMC2_HUMAN,Homo sapiens (Human),detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; vestibular reflex [GO:0060005] comp95535_c2_seq1,511,45.9883,0.4452191,24,16,,9.00E-24,Q920I9,WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG),WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG),,,PF00400;,,,,,,,,,WDR7_MOUSE,Mus musculus (Mouse),hematopoietic progenitor cell differentiation [GO:0002244] comp95536_c0_seq1,395,43.5443,0.64565631,2,19,,3.00E-16,Q9BX70,BTB/POZ domain-containing protein 2,BTB/POZ domain-containing protein 2,GO:0000932,cytoplasmic mRNA processing body,PF07707;PF00651;PF08005;,,,,,,,,,BTBD2_HUMAN,Homo sapiens (Human),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162] comp95552_c0_seq1,316,42.4051,0.43544392,5,38,,1.00E-07,Q2NKS2,"Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial","Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial",GO:0016021; GO:0031966,integral to membrane; mitochondrial membrane,PF14138;,,,,,,,,,COX16_BOVIN,Bos taurus (Bovine), comp95563_c0_seq1,879,41.2969,0.38092932,11,93,,3.00E-73,Q5ZJM3,Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase),Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase),GO:0005737; GO:0006516; GO:0046872; GO:0000224,cytoplasm; glycoprotein catabolic process; metal ion binding; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity,PF04721;PF09409;PF01841;,,,,,,,,,NGLY1_CHICK,Gallus gallus (Chicken),glycoprotein catabolic process [GO:0006516] comp95569_c0_seq1,508,46.063,0.5597529,7,6,,2.00E-63,B2RX12,Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3),Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3),GO:0005524; GO:0006200; GO:0042626; GO:0005887,"ATP binding; ATP catabolic process; ATPase activity, coupled to transmembrane movement of substances; integral to plasma membrane",PF00664;PF00005;,3.00E-19,CHOYP_LOC100742783.1.1,,,,,,,MRP3_MOUSE,Mus musculus (Mouse),canalicular bile acid transport [GO:0015722] comp95579_c0_seq1,622,40.0322,0.50898824,12,47,,7.00E-31,Q148E0,Thioredoxin-like protein AAED1 (AhpC/TSA antioxidant enzyme domain-containing protein 1),Thioredoxin-like protein AAED1 (AhpC/TSA antioxidant enzyme domain-containing protein 1),,,PF13911;,1.00E-26,CHOYP_C9ORF21.1.1,,,,,,,CI021_BOVIN,Bos taurus (Bovine), comp95587_c0_seq1,396,37.3737,0.4771665,16,80,,,,,,,,,3.00E-12,CHOYP_NEMVEDRAFT_V1G242858.1.1,,,,,,,,, comp95592_c0_seq2,210,42.381,0.96889952,0,7,,7.00E-25,Q9P0Z9,Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase),GO:0033514; GO:0050031; GO:0005777; GO:0008115; GO:0046653,L-lysine catabolic process to acetyl-CoA via L-pipecolate; L-pipecolate oxidase activity; peroxisome; sarcosine oxidase activity; tetrahydrofolate metabolic process,PF01266;,,,2.00E-14,ruditapes2_c2779,,,,,SOX_HUMAN,Homo sapiens (Human),L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; lysine catabolic process [GO:0006554]; oxidation-reduction process [GO:0055114]; tetrahydrofolate metabolic process [GO:0046653] comp95610_c0_seq1,284,45.0704,0.71322206,13,41,,4.00E-17,Q9D3D0,Alpha-tocopherol transfer protein-like,Alpha-tocopherol transfer protein-like,GO:0005622; GO:0005215,intracellular; transporter activity,PF00650;PF03765;,,,,,,,,,TTPAL_MOUSE,Mus musculus (Mouse), comp95617_c0_seq2,411,42.8224,0.26632349,13,19,,1.00E-54,Q6TH47,STAM-binding protein-like A (EC 3.4.19.-),STAM-binding protein-like A (EC 3.4.19.-),GO:0046872; GO:0008237; GO:0006508,metal ion binding; metallopeptidase activity; proteolysis,PF01398;PF08969;,1.00E-16,CHOYP_FA13A.1.2,,,,,,,STBPA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp95624_c0_seq1,718,42.6184,0.58560642,17,39,,8.00E-51,Q3MI05,Lysosomal protective protein (EC 3.4.16.5) (Cathepsin A) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain],Lysosomal protective protein (EC 3.4.16.5) (Cathepsin A) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain],GO:0005764; GO:0005634; GO:0006508; GO:0004185,lysosome; nucleus; proteolysis; serine-type carboxypeptidase activity,PF00450;,,,,,,,,,PPGB_BOVIN,Bos taurus (Bovine),proteolysis involved in cellular protein catabolic process [GO:0051603] comp95640_c1_seq1,279,39.0681,0.48611736,7,12,,,,,,,,,1.00E-14,CHOYP_LOC100496475.3.16,,,,,,,,, comp95644_c0_seq1,306,46.732,0.48100788,2,21,,3.00E-12,Q8AV57,Protein sidekick-2,Protein sidekick-2,GO:0007155; GO:0030054; GO:0016021; GO:0005886; GO:0045202,cell adhesion; cell junction; integral to membrane; plasma membrane; synapse,PF00041;PF07679;,,,,,,,,,SDK2_CHICK,Gallus gallus (Chicken),camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] comp95675_c0_seq1,299,36.1204,0.83017186,4,31,,7.00E-11,Q3V6T2,Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),GO:0006260; GO:0005794; GO:0031929; GO:0003779; GO:0032148; GO:0016477; GO:0016023; GO:0031410; GO:0005829; GO:0005783; GO:0030027; GO:0030032; GO:0061024; GO:0008017; GO:0035091; GO:0005886; GO:0006275; GO:0032956; GO:0042127; GO:0010975,DNA replication; Golgi apparatus; TOR signaling cascade; actin binding; activation of protein kinase B activity; cell migration; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; endoplasmic reticulum; lamellipodium; lamellipodium assembly; membrane organization; microtubule binding; phosphatidylinositol binding; plasma membrane; regulation of DNA replication; regulation of actin cytoskeleton organization; regulation of cell proliferation; regulation of neuron projection development,PF05622;,,,,,,,,,GRDN_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp95677_c0_seq1,341,46.6276,0.6955992,6,29,,3.00E-40,Q2XWK0,Synaptic vesicle 2-related protein (SV2-related protein),Synaptic vesicle 2-related protein (SV2-related protein),GO:0030054; GO:0016021; GO:0030672; GO:0022857,cell junction; integral to membrane; synaptic vesicle membrane; transmembrane transporter activity,PF07690;PF00083;,3.00E-61,CHOYP_LOC100375275.1.1,,,,,,,SVOP_XENLA,Xenopus laevis (African clawed frog), comp95690_c0_seq1,675,38.6667,0.28980955,22,28,,3.00E-08,Q5VVB8,Transmembrane protein 244,Transmembrane protein 244,GO:0016021,integral to membrane,,,,,,,,,,TM244_HUMAN,Homo sapiens (Human), comp95704_c0_seq1,499,33.0661,0.66313264,9,50,,2.00E-15,P18599,5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A),GO:0030424; GO:0007610; GO:0005901; GO:0016023; GO:0043198; GO:0005887; GO:0050795; GO:0046883; GO:0004993; GO:0007210; GO:0006939,axon; behavior; caveola; cytoplasmic membrane-bounded vesicle; dendritic shaft; integral to plasma membrane; regulation of behavior; regulation of hormone secretion; serotonin receptor activity; serotonin receptor signaling pathway; smooth muscle contraction,PF00001;,,,,,,,,,5HT2A_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),behavior [GO:0007610]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; smooth muscle contraction [GO:0006939] comp95709_c0_seq1,265,48.6792,0.70439135,8,0,,1.00E-20,Q8R420,ATP-binding cassette sub-family A member 3,ATP-binding cassette sub-family A member 3,GO:0005524; GO:0006200; GO:0016887; GO:0097233; GO:0016021; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; alveolar lamellar body membrane; integral to membrane; plasma membrane; transport,PF00005;,,,,,,,,,ABCA3_MOUSE,Mus musculus (Mouse),lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810] comp95716_c0_seq1,448,41.2946,0.908695,17,0,,7.00E-27,Q9MYM7,"Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)","Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)",GO:0000139; GO:0008378; GO:0016021; GO:0006486,Golgi membrane; galactosyltransferase activity; integral to membrane; protein glycosylation,PF01762;,,,,,,,,,B3GT1_PONPY,Pongo pygmaeus (Bornean orangutan),protein glycosylation [GO:0006486] comp95726_c1_seq1,477,43.6059,0.61894464,4,57,,,,,,,,,2.00E-20,CHOYP_GATA2.2.2,,,,,,,,, comp95735_c0_seq1,249,39.3574,0.52411747,4,22,,3.00E-06,Q97BG9,Chaperone protein DnaJ,Chaperone protein DnaJ,GO:0005524; GO:0006260; GO:0005737; GO:0006457; GO:0009408; GO:0008270,ATP binding; DNA replication; cytoplasm; protein folding; response to heat; zinc ion binding,PF00226;PF01556;PF00684;,,,,,,,,,DNAJ_THEVO,Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1),DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408] comp95736_c1_seq1,613,42.5775,0.6205724,13,50,,5.00E-67,P27465,Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain],"Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]",GO:0005739; GO:0006646; GO:0004609,mitochondrion; phosphatidylethanolamine biosynthetic process; phosphatidylserine decarboxylase activity,PF02666;,,,,,,,,,PISD_CRIGR,Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus),phospholipid biosynthetic process [GO:0008654] comp95737_c1_seq1,578,40.6574,0.46138938,23,27,,2.00E-23,A0JMF6,Myotubularin-related protein 10,Myotubularin-related protein 10,GO:0016791,phosphatase activity,PF12578;PF06602;,,,,,,,,,MTMRA_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp95740_c3_seq1,326,42.3313,0.48910717,3,24,,1.00E-49,A5HK05,Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2),Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2),GO:0030659; GO:0046907; GO:0005874; GO:0005634; GO:0015031,cytoplasmic vesicle membrane; intracellular transport; microtubule; nucleus; protein transport,PF13374;,9.00E-62,CHOYP_APBP2.1.1,,,,,,,APBP2_RAT,Rattus norvegicus (Rat),intracellular transport [GO:0046907]; protein transport [GO:0015031] comp95750_c0_seq1,410,42.1951,0.38462796,3,29,,2.00E-64,P52850,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (Mndns) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)],Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (Mndns) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)],GO:0005794; GO:0000139; GO:0015016; GO:0019213; GO:0006024; GO:0015012; GO:0030210; GO:0016021; GO:0002002,Golgi apparatus; Golgi membrane; [heparan sulfate]-glucosamine N-sulfotransferase activity; deacetylase activity; glycosaminoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; integral to membrane; regulation of angiotensin levels in blood,PF12062;PF00685;,3.00E-50,CHOYP_NDST.1.1,,,,,,,NDST2_MOUSE,Mus musculus (Mouse),cellular process [GO:0009987]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; regulation of angiotensin levels in blood [GO:0002002] comp95750_c0_seq2,262,38.5496,0.43115382,0,12,,3.00E-22,O97583,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (CCL44) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)],Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (CCL44) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)],GO:0000139; GO:0015016; GO:0015012; GO:0030210; GO:0016787; GO:0016021,Golgi membrane; [heparan sulfate]-glucosamine N-sulfotransferase activity; heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; hydrolase activity; integral to membrane,PF12062;PF00685;,,,,,,,,,NDST2_BOVIN,Bos taurus (Bovine),heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] comp95761_c0_seq1,313,45.6869,0.92137091,0,5,,1.00E-36,Q29P71,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,3.00E-49,CHOYP_MYO15.1.1,6.00E-74,ruditapes_c15733,,,,,MYO7A_DROPS,Drosophila pseudoobscura pseudoobscura (Fruit fly),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp95761_c0_seq2,264,48.8636,0.95554256,0,0,,2.00E-11,Q99323,"Myosin heavy chain, non-muscle (Myosin II) (Non-muscle MHC) (Zipper protein)","Myosin heavy chain, non-muscle (Myosin II) (Non-muscle MHC) (Zipper protein)",GO:0005524; GO:0042623; GO:0007443; GO:0030018; GO:0007496; GO:0045179; GO:0007298; GO:0032154; GO:0035017; GO:0046664; GO:0046663; GO:0007395; GO:0045200; GO:0001736; GO:0045184; GO:0008258; GO:0035317; GO:0070986; GO:0003774; GO:0006936; GO:0016460; GO:0031036; GO:0051259; GO:0051726; GO:0035159; GO:0007435; GO:0045214; GO:0016461; GO:0042060,"ATP binding; ATPase activity, coupled; Malpighian tubule morphogenesis; Z disc; anterior midgut development; apical cortex; border follicle cell migration; cleavage furrow; cuticle pattern formation; dorsal closure, amnioserosa morphology change; dorsal closure, leading edge cell differentiation; dorsal closure, spreading of leading edge cells; establishment of neuroblast polarity; establishment of planar polarity; establishment of protein localization; head involution; imaginal disc-derived wing hair organization; left/right axis specification; motor activity; muscle contraction; myosin II complex; myosin II filament assembly; protein oligomerization; regulation of cell cycle; regulation of tube length, open tracheal system; salivary gland morphogenesis; sarcomere organization; unconventional myosin complex; wound healing",PF00612;PF00063;PF02736;PF01576;,,,,,,,,,MYSN_DROME,Drosophila melanogaster (Fruit fly),"anterior midgut development [GO:0007496]; border follicle cell migration [GO:0007298]; cellular response to mechanical stimulus [GO:0071260]; cuticle pattern formation [GO:0035017]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, leading edge cell differentiation [GO:0046663]; dorsal closure, spreading of leading edge cells [GO:0007395]; establishment of neuroblast polarity [GO:0045200]; establishment of planar polarity [GO:0001736]; head involution [GO:0008258]; imaginal disc-derived wing hair organization [GO:0035317]; left/right axis specification [GO:0070986]; maintenance of protein location in cell [GO:0032507]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cytokinesis [GO:0000281]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; myosin II filament assembly [GO:0031036]; neurogenesis [GO:0022008]; ovarian follicle cell migration [GO:0007297]; protein oligomerization [GO:0051259]; regulation of cell cycle [GO:0051726]; regulation of myoblast fusion [GO:1901739]; regulation of tube length, open tracheal system [GO:0035159]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; spiracle morphogenesis, open tracheal system [GO:0035277]; wound healing [GO:0042060]" comp95765_c0_seq1,421,41.0926,0.40621791,9,28,,1.00E-23,Q719N1,Spastin (EC 3.6.4.3) (Fragment),Spastin (EC 3.6.4.3),GO:0005524; GO:0006888; GO:0043014; GO:0048487; GO:0030154; GO:0007109; GO:0005783; GO:0005768; GO:0016021; GO:0005874; GO:0008017; GO:0001578; GO:0005815; GO:0051013; GO:0008568; GO:0007399; GO:0005634; GO:0048471; GO:0034214; GO:0051260; GO:0005819,"ATP binding; ER to Golgi vesicle-mediated transport; alpha-tubulin binding; beta-tubulin binding; cell differentiation; cytokinesis, completion of separation; endoplasmic reticulum; endosome; integral to membrane; microtubule; microtubule binding; microtubule bundle formation; microtubule organizing center; microtubule severing; microtubule-severing ATPase activity; nervous system development; nucleus; perinuclear region of cytoplasm; protein hexamerization; protein homooligomerization; spindle",PF00004;PF09336;,,,,,,,,,SPAST_PIG,Sus scrofa (Pig),anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; cytoplasmic microtubule organization [GO:0031122]; ER to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; metabolic process [GO:0008152]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear envelope reassembly [GO:0031468]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260] comp95770_c1_seq1,312,41.9872,0.87963433,0,45,,2.00E-08,Q5DRD4,Protocadherin beta-18 (PCDH-beta-18) (Protocadherin beta-17),Protocadherin beta-18 (PCDH-beta-18) (Protocadherin beta-17),GO:0005509; GO:0007156; GO:0016021; GO:0005886,calcium ion binding; homophilic cell adhesion; integral to membrane; plasma membrane,PF00028;PF08266;PF16492;,,,,,,,,,PCDBI_PANTR,Pan troglodytes (Chimpanzee),homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] comp95773_c1_seq1,234,44.0171,0.81472983,9,0,,2.00E-06,Q09575,Uncharacterized protein K02A2.6,Uncharacterized protein K02A2.6,GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0008270,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; zinc ion binding,PF00665;PF00078;,,,,,,,,,YRD6_CAEEL,Caenorhabditis elegans,DNA integration [GO:0015074] comp95775_c0_seq1,246,55.6911,1.00451146,0,9,,1.00E-19,O33294,Putative ribonuclease J Rv2752c (RNase J) (EC 3.1.-.-),,GO:0003723; GO:0005737; GO:0004519; GO:0046872; GO:0090305,RNA binding; cytoplasm; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis,,,,,,,,,,Y2752_MYCTU,, comp95778_c0_seq1,234,43.5897,0.73295686,4,0,,1.00E-35,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,1.00E-33,CHOYP_LOC100056407.1.1,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp95790_c0_seq1,266,59.0226,1.299921,0,10,,5.00E-33,O06134,Pyruvate kinase (PK) (EC 2.7.1.40),,GO:0005524; GO:0005829; GO:0006096; GO:0040007; GO:0000287; GO:0005886; GO:0030955; GO:0004743,ATP binding; cytosol; glycolysis; growth; magnesium ion binding; plasma membrane; potassium ion binding; pyruvate kinase activity,,,,,,,,,,KPYK_MYCTU,, comp95798_c0_seq1,211,50.237,0.22674306,4,24,,3.00E-12,B0S6R1,Nck-associated protein 1 (NAP 1),Nck-associated protein 1 (NAP 1),GO:0016021; GO:0031258,integral to membrane; lamellipodium membrane,PF09735;,6.00E-11,CHOYP_NCKP1.2.4,,,,,,,NCKP1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp95801_c0_seq1,445,47.6404,0.9342488,17,5,,2.00E-34,P0C6B8,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_RAT,Rattus norvegicus (Rat),cell adhesion [GO:0007155] comp95801_c1_seq1,265,44.9057,0.71293451,5,0,,8.00E-17,O88278,Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2),GO:0004930; GO:0007413; GO:0005509; GO:0042384; GO:0007156; GO:0016021; GO:0001764; GO:0007218; GO:0005886; GO:0032880,G-protein coupled receptor activity; axonal fasciculation; calcium ion binding; cilium assembly; homophilic cell adhesion; integral to membrane; neuron migration; neuropeptide signaling pathway; plasma membrane; regulation of protein localization,PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;,,,,,,,,,CELR3_RAT,Rattus norvegicus (Rat),axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] comp95827_c0_seq1,387,46.2532,0.89539059,0,54,,1.00E-15,O49561,Gibberellin 2-beta-dioxygenase 8 (EC 1.14.11.13) (GA 2-oxidase 8) (Gibberellin 2-beta-hydroxylase 8) (Gibberellin 2-oxidase 8),Gibberellin 2-beta-dioxygenase 8 (EC 1.14.11.13) (GA 2-oxidase 8) (Gibberellin 2-beta-hydroxylase 8) (Gibberellin 2-oxidase 8),GO:0052635; GO:0009686; GO:0009685; GO:0046872,C-20 gibberellin 2-beta-dioxygenase activity; gibberellin biosynthetic process; gibberellin metabolic process; metal ion binding,PF03171;PF14226;,,,1.00E-27,ruditapes_c27218,,,,,G2OX8_ARATH,Arabidopsis thaliana (Mouse-ear cress),gibberellin biosynthetic process [GO:0009686]; gibberellin metabolic process [GO:0009685] comp95833_c0_seq2,435,45.977,0.17616255,9,0,,2.00E-29,A6QM06,Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),GO:0012507; GO:0000139; GO:0008203; GO:0005789; GO:0016021,ER to Golgi transport vesicle membrane; Golgi membrane; cholesterol metabolic process; endoplasmic reticulum membrane; integral to membrane,PF12349;PF00400;,6.00E-21,CHOYP_BRAFLDRAFT_118545.2.2,,,,,,,SCAP_BOVIN,Bos taurus (Bovine),cholesterol metabolic process [GO:0008203]; SREBP signaling pathway [GO:0032933] comp95880_c1_seq1,436,45.4128,0.40194386,6,22,,6.00E-52,Q149N8,"E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)","E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)",GO:0005524; GO:0003677; GO:0006281; GO:0004386; GO:0016874; GO:0000786; GO:0006334; GO:0005634; GO:0016567; GO:0008270,ATP binding; DNA binding; DNA repair; helicase activity; ligase activity; nucleosome; nucleosome assembly; nucleus; protein ubiquitination; zinc ion binding,PF00271;PF00538;PF00176;,6.00E-40,CHOYP_SHPRH.3.3,,,,,,,SHPRH_HUMAN,Homo sapiens (Human),cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] comp95888_c0_seq1,428,42.2897,0.52394033,7,34,,2.00E-65,Q9W3K5,Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase),Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase),GO:0005524; GO:0004357; GO:0017109; GO:0006750; GO:0005634; GO:0048471; GO:0006974,ATP binding; glutamate-cysteine ligase activity; glutamate-cysteine ligase complex; glutathione biosynthetic process; nucleus; perinuclear region of cytoplasm; response to DNA damage stimulus,PF03074;,2.00E-65,CHOYP_GSH1.1.1,,,,,,,GSH1_DROME,Drosophila melanogaster (Fruit fly),cellular response to DNA damage stimulus [GO:0006974]; glutathione biosynthetic process [GO:0006750]; glutathione metabolic process [GO:0006749] comp95907_c0_seq1,355,39.1549,0.76166629,15,39,,5.00E-12,Q6RFH5,WD repeat-containing protein 74 (NOP seven-associated protein 1),WD repeat-containing protein 74 (NOP seven-associated protein 1),GO:0016070; GO:0001825; GO:0005730,RNA metabolic process; blastocyst formation; nucleolus,PF00400;,,,,,,,,,WDR74_HUMAN,Homo sapiens (Human),blastocyst formation [GO:0001825]; ribosomal large subunit biogenesis [GO:0042273]; RNA metabolic process [GO:0016070] comp95925_c0_seq1,621,43.4783,0.37593504,8,43,,5.00E-97,Q5NDL3,EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase),GO:0005788; GO:0016262; GO:0006493,endoplasmic reticulum lumen; protein N-acetylglucosaminyltransferase activity; protein O-linked glycosylation,PF04577;,3.00E-59,CHOYP_MED24.4.10,,,,,,,EOGT_CHICK,Gallus gallus (Chicken),protein O-linked glycosylation [GO:0006493] comp95925_c0_seq2,325,43.0769,0.46581376,0,5,,,,,,,,,,,1.00E-51,ruditapes_c25391,,,,,,, comp95939_c0_seq1,640,43.75,0.29439753,37,0,,1.00E-19,Q5VVC0,Uncharacterized protein C1orf146,Uncharacterized protein C1orf146,,,PF15162;,,,,,,,,,CA146_HUMAN,Homo sapiens (Human), comp95941_c0_seq1,379,42.2164,0.49231112,14,22,,2.00E-32,Q96JB1,"Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)","Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)",GO:0005524; GO:0006200; GO:0016887; GO:0005858; GO:0001539; GO:0035085; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; axonemal dynein complex; ciliary or bacterial-type flagellar motility; cilium axoneme; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,4.00E-79,CHOYP_DNAH5.2.2,,,,,,,DYH8_HUMAN,Homo sapiens (Human),cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018] comp95961_c0_seq1,230,40.8696,0.63202289,5,0,,5.00E-18,Q96A29,GDP-fucose transporter 1 (Solute carrier family 35 member C1),GDP-fucose transporter 1 (Solute carrier family 35 member C1),GO:0000139; GO:0008643; GO:0016021; GO:0030259; GO:0045746; GO:0055085,Golgi membrane; carbohydrate transport; integral to membrane; lipid glycosylation; negative regulation of Notch signaling pathway; transmembrane transport,PF03151;,,,,,,,,,FUCT1_HUMAN,Homo sapiens (Human),carbohydrate transport [GO:0008643]; lipid glycosylation [GO:0030259]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp95969_c0_seq1,263,33.4601,1.56552129,8,41,,,,,,,,,2.00E-11,CHOYP_LOC100561123.8.28,,,,,,,,, comp95982_c0_seq1,202,41.0891,0.2360523,0,0,,6.00E-11,Q3U0J8,TBC1 domain family member 2B,TBC1 domain family member 2B,GO:0005097; GO:0005543; GO:0032851,Rab GTPase activator activity; phospholipid binding; positive regulation of Rab GTPase activity,PF00169;PF00566;,,,,,,,,,TBD2B_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338] comp95991_c0_seq1,337,42.4332,0.39827531,8,4,,4.00E-18,Q9NSN8,Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4),Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4),GO:0007154; GO:0005737; GO:0005856; GO:0005634; GO:0005543; GO:0032587; GO:0016013,cell communication; cytoplasm; cytoskeleton; nucleus; phospholipid binding; ruffle membrane; syntrophin complex,PF00595;,3.00E-23,CHOYP_LOC659142.1.1,,,,,,,SNTG1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792] comp95991_c2_seq1,407,46.9287,0.4927566,4,28,,3.00E-26,Q925E0,Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5),Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5),GO:0005737; GO:0005856; GO:0005543; GO:0042383,cytoplasm; cytoskeleton; phospholipid binding; sarcolemma,PF00595;,,,,,,,,,SNTG2_MOUSE,Mus musculus (Mouse), comp95996_c0_seq1,284,47.5352,0.37632509,12,18,,,,,,,,,7.00E-43,CHOYP_LOC100489553.12.14,,,,,,,,, comp95_c0_seq1,236,40.678,0.61961897,2,5,,7.00E-32,Q8K358,Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U),Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U),GO:0006506; GO:0042765,GPI anchor biosynthetic process; GPI-anchor transamidase complex,PF06728;,2.00E-24,CHOYP_LOC581221.1.1,,,,,,,PIGU_MOUSE,Mus musculus (Mouse),attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; regulation of JAK-STAT cascade [GO:0046425] comp96013_c0_seq1,212,39.6226,1.21370222,7,10,,,,,,,,,6.00E-17,CHOYP_LOC100491922.2.5,,,,,,,,, comp96023_c0_seq1,415,39.0361,0.70012646,12,28,,4.00E-11,Q0VAW7,Zinc finger protein 112 (Zfp-112),Zinc finger protein 112 (Zfp-112),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZF112_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp96028_c0_seq1,395,46.3291,0.61491077,8,53,,5.00E-74,O43679,LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1),LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1),GO:0030274; GO:0010669; GO:0001942; GO:0005634; GO:0044089; GO:0045944; GO:0035019; GO:0003712; GO:0005667,LIM domain binding; epithelial structure maintenance; hair follicle development; nucleus; positive regulation of cellular component biogenesis; positive regulation of transcription from RNA polymerase II promoter; somatic stem cell maintenance; transcription cofactor activity; transcription factor complex,,5.00E-79,CHOYP_LOC657473.1.1,,,,,,,LDB2_HUMAN,Homo sapiens (Human),epithelial structure maintenance [GO:0010669]; hair follicle development [GO:0001942]; positive regulation of cellular component biogenesis [GO:0044089]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of kinase activity [GO:0043549]; somatic stem cell population maintenance [GO:0035019] comp96031_c0_seq1,460,45.6522,0.76833696,11,12,,5.00E-44,Q8TBP0,TBC1 domain family member 16,TBC1 domain family member 16,GO:0005097; GO:0032851,Rab GTPase activator activity; positive regulation of Rab GTPase activity,PF00566;,,,,,,,,,TBC16_HUMAN,Homo sapiens (Human),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of receptor recycling [GO:0001919]; regulation of vesicle fusion [GO:0031338] comp96045_c0_seq1,332,47.2892,0.38276209,7,1,,,,,,,,,,,3.00E-21,ruditapes_c30069,,,,,,, comp96045_c1_seq1,317,42.9022,0.50602913,5,15,,1.00E-30,Q9D3S3,Sorting nexin-29,Sorting nexin-29,GO:0007154; GO:0035091,cell communication; phosphatidylinositol binding,PF00787;PF02759;,2.00E-24,CHOYP_SNX29.1.1,,,,,,,SNX29_MOUSE,Mus musculus (Mouse), comp96049_c1_seq1,284,44.3662,0.14365097,14,2,,2.00E-29,Q3UZW7,Protein FAM86A,Protein-lysine N-methyltransferase EEF2KMT (EC 2.1.1.-) (eEF2-lysine methyltransferase) (eEF2-KMT),GO:0005737,cytoplasm,PF14904;PF10294;,2.00E-11,CHOYP_LOC100889152.1.1,,,,,,,FA86A_MOUSE,Mus musculus (Mouse),peptidyl-lysine trimethylation [GO:0018023] comp96064_c0_seq1,1056,41.9508,0.25854079,37,66,,,,,,,,,2.00E-45,CHOYP_NEMVEDRAFT_V1G241328.1.1,,,,,,,,, comp96068_c0_seq1,541,44.732,0.37143767,17,32,,3.00E-99,Q9R1A8,E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2),E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2),GO:0005813; GO:0005737; GO:0005925; GO:0016874; GO:0016607; GO:0016567; GO:0008270,centrosome; cytoplasm; focal adhesion; ligase activity; nuclear speck; protein ubiquitination; zinc ion binding,PF00400;,2.00E-97,CHOYP_RFWD2.1.1,,,,,,,RFWD2_MOUSE,Mus musculus (Mouse),positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; response to ionizing radiation [GO:0010212] comp96086_c0_seq1,392,47.449,0.60070938,9,14,,9.00E-24,Q80TQ5,Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),GO:0007030; GO:0005737; GO:0005543,Golgi organization; cytoplasm; phospholipid binding,PF00169;PF02759;,,,,,,,,,PKHM2_MOUSE,Mus musculus (Mouse),Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880] comp96136_c1_seq1,268,46.6418,0.27689526,9,0,,1.00E-06,Q63HN8,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,PF00097;,,,,,,,,,RN213_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp96152_c0_seq1,454,46.0352,0.41943419,21,8,,2.00E-76,Q8NFA0,Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32),GO:0005794; GO:0005509; GO:0008234; GO:0016020; GO:0016579; GO:0004221; GO:0006511,Golgi apparatus; calcium ion binding; cysteine-type peptidase activity; membrane; protein deubiquitination; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process,PF06337;PF13202;PF14836;PF00443;,5.00E-67,CHOYP_UBP32.1.1,,,,,,,UBP32_HUMAN,Homo sapiens (Human),protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] comp96183_c1_seq1,463,47.9482,0.8661675,10,46,,4.00E-08,Q8IZJ3,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8,GO:0005615; GO:0010951; GO:0005886; GO:0004867,extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;,,,,,,,,,CPMD8_HUMAN,Homo sapiens (Human), comp96185_c1_seq1,614,45.2769,0.54123455,19,46,,6.00E-50,Q969W1,Probable palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 16) (DHHC-16),Probable palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16),GO:0006915; GO:0005789; GO:0016021; GO:0016746; GO:0008270,"apoptotic process; endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF01529;,2.00E-16,CHOYP_PHUM_PHUM003160.1.1,,,,,,,ZDH16_HUMAN,Homo sapiens (Human),apoptotic process [GO:0006915]; protein palmitoylation [GO:0018345] comp96199_c0_seq1,276,38.0435,1.00948847,2,30,,3.00E-06,P33263,Cytochrome P450 2C26 (EC 1.14.14.1) (CYPIIC26) (Cytochrome P450 HSM2),Cytochrome P450 2C26 (EC 1.14.14.1) (CYPIIC26) (Cytochrome P450 HSM2),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,,,,,,,,,CP2CQ_MESAU,Mesocricetus auratus (Golden hamster), comp96202_c0_seq1,385,43.8961,1.08214916,0,48,,9.00E-16,Q7Z4N8,"Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3)","Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3)",GO:0031418; GO:0005788; GO:0005506; GO:0016702; GO:0004656,"L-ascorbic acid binding; endoplasmic reticulum lumen; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; procollagen-proline 4-dioxygenase activity",PF13640;PF08336;,,,,,,,,,P4HA3_HUMAN,Homo sapiens (Human), comp96212_c0_seq1,329,45.8967,0.46479303,20,22,,9.00E-25,Q7K480,Probable RNA methyltransferase bin3 (EC 2.1.1.-) (Bicoid-interacting protein 3),Probable RNA methyltransferase bin3 (EC 2.1.1.-) (Bicoid-interacting protein 3),GO:0032502; GO:0008168; GO:0017148; GO:0042048; GO:0017069,developmental process; methyltransferase activity; negative regulation of translation; olfactory behavior; snRNA binding,PF06859;PF13847;,,,,,,,,,BN3D1_DROME,Drosophila melanogaster (Fruit fly),developmental process [GO:0032502]; methylation [GO:0032259]; negative regulation of translation [GO:0017148]; olfactory behavior [GO:0042048] comp96212_c1_seq1,523,40.3442,0.570601,16,10,,2.00E-62,Q8K3A9,7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-),7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-),GO:0008173; GO:0008757; GO:0035562; GO:0000122; GO:1900087; GO:0040031,RNA methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; negative regulation of chromatin binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of G1/S transition of mitotic cell cycle; snRNA modification,PF06859;PF13847;,3.00E-38,CHOYP_LOC100879901.1.1,,,,,,,MEPCE_MOUSE,Mus musculus (Mouse),negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031] comp96213_c0_seq1,371,30.9973,0.45421575,7,20,,,,,,,,,7.00E-13,CHOYP_LOC100562697.1.1,,,,,,,,, comp96219_c0_seq1,210,65.7143,0.88383838,0,28,,5.00E-15,Q9ZT05,"Photosystem I reaction center subunit psaK, chloroplastic (PSI-K) (Photosystem I subunit X)","Photosystem I reaction center subunit psaK, chloroplastic (PSI-K) (Photosystem I subunit X)",GO:0016168; GO:0009535; GO:0016021; GO:0015979; GO:0009522,chlorophyll binding; chloroplast thylakoid membrane; integral to membrane; photosynthesis; photosystem I,PF01241;,,,,,,,,,PSAK_MEDSA,Medicago sativa (Alfalfa),photosynthesis [GO:0015979] comp9621_c0_seq1,309,44.3366,1.06393221,3,3,,4.00E-06,Q7ZXS8,Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor),Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor),GO:0004948; GO:0016021; GO:0005886,calcitonin receptor activity; integral to membrane; plasma membrane,PF00002;PF02793;,,,,,,,,,CALRL_XENLA,Xenopus laevis (African clawed frog),cell surface receptor signaling pathway [GO:0007166] comp96229_c0_seq1,701,39.3723,0.66355226,4,64,,7.00E-24,Q5JVG2,Zinc finger protein 484,Zinc finger protein 484,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN484_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp96238_c0_seq1,275,40,0.42057699,2,0,,2.00E-16,Q92994,"Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2)","Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2)",GO:0005654; GO:0045893; GO:0009303; GO:0043488; GO:0009304; GO:0000126; GO:0006384; GO:0008270,"nucleoplasm; positive regulation of transcription, DNA-dependent; rRNA transcription; regulation of mRNA stability; tRNA transcription; transcription factor TFIIIB complex; transcription initiation from RNA polymerase III promoter; zinc ion binding",PF07741;PF08271;PF00382;,,,,,,,,,TF3B_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; rRNA transcription [GO:0009303]; transcription from RNA polymerase III promoter [GO:0006383]; transcription initiation from RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]" comp96242_c0_seq1,442,38.4615,0.76281062,16,22,,2.00E-23,Q9VCG3,Putative OPA3-like protein CG13603,Putative OPA3-like protein CG13603,,,PF07047;,,,,,,,,,OPA32_DROME,Drosophila melanogaster (Fruit fly),regulation of lipid metabolic process [GO:0019216] comp96252_c0_seq1,251,47.4104,0.28475028,20,7,,7.00E-07,Q5THJ4,Vacuolar protein sorting-associated protein 13D,Vacuolar protein sorting-associated protein 13D,,,PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;,,,,,,,,,VP13D_HUMAN,Homo sapiens (Human),protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] comp96255_c0_seq1,346,46.8208,0.63621616,2,26,,9.00E-38,Q802D3,Exportin-4,Exportin-4,GO:0005737; GO:0005634; GO:0015031,cytoplasm; nucleus; protein transport,PF08767;,2.00E-39,CHOYP_XPO4.1.1,,,,,,,XPO4_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),protein export from nucleus [GO:0006611] comp96263_c0_seq1,682,47.3607,0.42150827,24,40,,3.00E-87,Q9D6M3,Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22),Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22),GO:0005313; GO:0016021; GO:0005743; GO:0005634; GO:0015293,L-glutamate transmembrane transporter activity; integral to membrane; mitochondrial inner membrane; nucleus; symporter activity,PF00153;,8.00E-41,CHOYP_DYAK_GE26151.1.1,,,,,,,GHC1_MOUSE,Mus musculus (Mouse),L-glutamate transport [GO:0015813]; translation [GO:0006412] comp96304_c0_seq1,276,42.029,0.75546446,4,9,,2.00E-26,Q96RE9,Zinc finger protein 300,Zinc finger protein 300,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF01352;PF00096;,,,,,,,,,ZN300_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp96321_c0_seq1,349,38.9685,0.38682899,17,20,,5.00E-25,Q3T0W7,Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like),Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like),GO:0000045; GO:0045087; GO:0034045,autophagic vacuole assembly; innate immune response; pre-autophagosomal structure membrane,PF04110;,6.00E-26,CHOYP_LOC100369330.1.1,7.00E-23,ruditapes_c23093,,,,,ATG12_BOVIN,Bos taurus (Bovine),autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; innate immune response [GO:0045087]; mitophagy [GO:0000422]; nucleophagy [GO:0044804] comp96324_c0_seq1,638,45.6113,0.36221157,31,41,,6.00E-16,Q9Y4E8,Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4),Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4),GO:0030509; GO:0004197; GO:0005737; GO:0035520; GO:0030512; GO:0005634; GO:0060389; GO:0007179; GO:0004221; GO:0006511; GO:0004843,BMP signaling pathway; cysteine-type endopeptidase activity; cytoplasm; monoubiquitinated protein deubiquitination; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; pathway-restricted SMAD protein phosphorylation; transforming growth factor beta receptor signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; ubiquitin-specific protease activity,PF06337;PF14836;PF00443;PF14533;,9.00E-15,CHOYP_LOC100369578.1.1,,,,,,,UBP15_HUMAN,Homo sapiens (Human),BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] comp96333_c0_seq1,545,56.5138,0.80796822,11,50,,4.00E-60,Q9UI36,Dachshund homolog 1 (Dach1),Dachshund homolog 1 (Dach1),GO:0003677; GO:0001078; GO:0001075; GO:0008283; GO:0005737; GO:0046545; GO:0030336; GO:0060244; GO:0048147; GO:0010944; GO:0005730; GO:0000166; GO:0007585; GO:0001967; GO:0005667,DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly; cell proliferation; cytoplasm; development of primary female sexual characteristics; negative regulation of cell migration; negative regulation of cell proliferation involved in contact inhibition; negative regulation of fibroblast proliferation; negative regulation of transcription by competitive promoter binding; nucleolus; nucleotide binding; respiratory gaseous exchange; suckling behavior; transcription factor complex,PF02437;,3.00E-51,CHOYP_PHUM_PHUM350510.1.1,,,,,,,DACH1_HUMAN,Homo sapiens (Human),"cell proliferation [GO:0008283]; development of primary female sexual characteristics [GO:0046545]; multicellular organism development [GO:0007275]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; regulation of nuclear cell cycle DNA replication [GO:0033262]; respiratory gaseous exchange [GO:0007585]; suckling behavior [GO:0001967]" comp96336_c2_seq1,453,44.3709,0.58447502,9,26,,3.00E-30,Q8VBW5,HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2),HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2),GO:0003677; GO:0060348; GO:0005634; GO:0006355; GO:0006351,"DNA binding; bone development; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF09667;PF00505;,3.00E-25,CHOYP_LOC100313559.1.1,,,,,,,BBX_MOUSE,Mus musculus (Mouse),"bone development [GO:0060348]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp96347_c0_seq1,478,39.9582,0.58041673,26,19,,6.00E-16,O00519,Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1),Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1),GO:0047372; GO:0016884; GO:0005737; GO:0005856; GO:0012505; GO:0017064; GO:0009062; GO:0016021; GO:0031090,"acylglycerol lipase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; cytoplasm; cytoskeleton; endomembrane system; fatty acid amide hydrolase activity; fatty acid catabolic process; integral to membrane; organelle membrane",PF01425;,,,3.00E-29,ruditapes_c22874,,,,,FAAH1_HUMAN,Homo sapiens (Human),arachidonic acid metabolic process [GO:0019369]; fatty acid catabolic process [GO:0009062] comp96362_c0_seq1,409,41.5648,0.34067507,11,0,,8.00E-10,Q6P9J9,Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F),Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F),GO:0007596; GO:0005227; GO:0005254; GO:0034707; GO:0017121; GO:0005886; GO:0005244,blood coagulation; calcium activated cation channel activity; chloride channel activity; chloride channel complex; phospholipid scrambling; plasma membrane; voltage-gated ion channel activity,PF16178;PF04547;,7.00E-26,CHOYP_BRAFLDRAFT_126668.2.2,,,,,,,ANO6_MOUSE,Mus musculus (Mouse),"activation of blood coagulation via clotting cascade [GO:0002543]; bleb assembly [GO:0032060]; blood coagulation [GO:0007596]; bone mineralization involved in bone maturation [GO:0035630]; calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; calcium activated phospholipid scrambling [GO:0061588]; calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; dendritic cell chemotaxis [GO:0002407]; negative regulation of cell volume [GO:0045794]; phosphatidylserine exposure on blood platelet [GO:0097045]; phospholipid scrambling [GO:0017121]; pore complex assembly [GO:0046931]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of potassium ion export [GO:1902304]; purinergic nucleotide receptor signaling pathway [GO:0035590]; sodium ion transmembrane transport [GO:0035725]" comp96362_c1_seq1,268,44.403,0.45983546,7,0,,1.00E-08,Q6IFT6,Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G),Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G),GO:0005254; GO:0005783; GO:0016021; GO:0005634; GO:0005886,chloride channel activity; endoplasmic reticulum; integral to membrane; nucleus; plasma membrane,PF16178;PF04547;,4.00E-20,CHOYP_BRAFLDRAFT_126668.1.2,,,,,,,ANO7_RAT,Rattus norvegicus (Rat),calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589] comp96377_c0_seq1,375,40.2667,0.7833389,8,11,,9.00E-39,Q58DA6,UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT),GO:0000139; GO:0016021; GO:0005338; GO:0015780; GO:0005351,Golgi membrane; integral to membrane; nucleotide-sugar transmembrane transporter activity; nucleotide-sugar transport; sugar:hydrogen symporter activity,PF04142;,6.00E-33,CHOYP_LOC100372949.1.1,,,,,,,S35A2_BOVIN,Bos taurus (Bovine), comp96403_c0_seq1,453,42.3841,0.39478453,18,36,,1.00E-60,Q9CXF4,TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP),GO:0005097; GO:0005576; GO:0005739,Rab GTPase activator activity; extracellular region; mitochondrion,PF12068;PF00566;,5.00E-86,CHOYP_TBC15.1.1,,,,,,,TBC15_MOUSE,Mus musculus (Mouse),activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338] comp96404_c0_seq1,578,42.9066,1.05547191,5,52,,6.00E-07,P05182,Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) (Cytochrome P450RLM6),Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) (Cytochrome P450RLM6),GO:0010181; GO:0000139; GO:0017144; GO:0020037; GO:0046483; GO:0031227; GO:0005506; GO:0005739; GO:0016098; GO:0016709; GO:0016712; GO:0042493; GO:0045471; GO:0010243; GO:0010193; GO:0008202; GO:0006641; GO:0006805,"FMN binding; Golgi membrane; drug metabolic process; heme binding; heterocycle metabolic process; intrinsic to endoplasmic reticulum membrane; iron ion binding; mitochondrion; monoterpenoid metabolic process; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; response to drug; response to ethanol; response to organonitrogen compound; response to ozone; steroid metabolic process; triglyceride metabolic process; xenobiotic metabolic process",PF00067;,,,,,,,,,CP2E1_RAT,Rattus norvegicus (Rat),drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; heterocycle metabolic process [GO:0046483]; monoterpenoid metabolic process [GO:0016098]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to organonitrogen compound [GO:0010243]; response to ozone [GO:0010193]; steroid metabolic process [GO:0008202]; triglyceride metabolic process [GO:0006641]; xenobiotic metabolic process [GO:0006805] comp96412_c0_seq1,934,42.0771,0.12111413,3,28,,5.00E-10,Q571H0,Nucleolar pre-ribosomal-associated protein 1 (URB1 ribosome biogenesis 1 homolog),Nucleolar pre-ribosomal-associated protein 1 (URB1 ribosome biogenesis 1 homolog),GO:0005730,nucleolus,PF16201;PF11707;,,,,,,,,,NPA1P_MOUSE,Mus musculus (Mouse), comp96413_c0_seq1,760,46.4474,0.51369424,33,61,,7.00E-13,Q5RI56,Optineurin,Optineurin,GO:0005737,cytoplasm,PF16516;PF11577;,2.00E-12,CHOYP_LOC100376215.13.19,,,,,,,OPTN_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),autophagy [GO:0006914]; axonogenesis [GO:0007409]; Golgi ribbon formation [GO:0090161]; protein targeting to Golgi [GO:0000042]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; vesicle localization [GO:0051648] comp96434_c0_seq1,371,58.7601,0.98061937,0,14,,2.00E-07,P31637,Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3),Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3),GO:0006020; GO:0016021; GO:0015798; GO:0007422; GO:0043576; GO:0006814; GO:0015293,inositol metabolic process; integral to membrane; myo-inositol transport; peripheral nervous system development; regulation of respiratory gaseous exchange; sodium ion transport; symporter activity,PF00474;,,,,,,,,,SC5A3_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),inositol metabolic process [GO:0006020]; myo-inositol transport [GO:0015798]; peripheral nervous system development [GO:0007422]; regulation of respiratory gaseous exchange [GO:0043576] comp96501_c0_seq1,330,55.4545,1.13163432,0,50,,1.00E-17,O53447,"Fructose-1,6-bisphosphatase class 2 (FBPase class 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2)",,GO:0005829; GO:0042132; GO:0006094; GO:0006071; GO:0046872,"cytosol; fructose 1,6-bisphosphate 1-phosphatase activity; gluconeogenesis; glycerol metabolic process; metal ion binding",,,,,,,,,,GLPX_MYCTU,, comp96523_c0_seq1,233,44.206,1.05964216,0,4,,8.00E-06,Q86YT5,Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter),Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter),GO:0016323; GO:0015137; GO:0016021; GO:0005886; GO:0017153; GO:0015141; GO:0055085,basolateral plasma membrane; citrate transmembrane transporter activity; integral to membrane; plasma membrane; sodium:dicarboxylate symporter activity; succinate transmembrane transporter activity; transmembrane transport,PF00939;,,,,,,,,,S13A5_HUMAN,Homo sapiens (Human),citrate transport [GO:0015746]; tricarboxylic acid transmembrane transport [GO:0035674] comp96542_c0_seq1,239,45.6067,0.49181189,0,36,,1.00E-10,Q6ZWJ8,Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1),Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1),GO:0005576,extracellular region,PF00093;PF00094;,,,,,,,,,KCP_HUMAN,Homo sapiens (Human),positive regulation of BMP signaling pathway [GO:0030513] comp96580_c0_seq1,441,46.712,0.87790104,6,49,,2.00E-14,O35490,Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5),GO:0006579; GO:0047150; GO:0005737; GO:0008898; GO:0009086; GO:0008270,amino-acid betaine catabolic process; betaine-homocysteine S-methyltransferase activity; cytoplasm; homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding,PF02574;,9.00E-32,CHOYP_LOC100371248.2.2,,,,,,,BHMT1_MOUSE,Mus musculus (Mouse),amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086] comp96589_c0_seq1,376,42.0213,1.02758463,14,36,,6.00E-17,Q6YND2,Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67),Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,3.00E-11,CHOYP_ZN454.1.1,,,,,,,ZN653_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp9658_c0_seq1,271,31.3653,0.75389053,4,0,,,,,,,,,1.00E-13,CHOYP_NEMVEDRAFT_V1G232141.1.1,,,,,,,,, comp96605_c1_seq1,331,46.2236,0.40474072,11,13,,1.00E-09,Q6ZS81,WD repeat- and FYVE domain-containing protein 4,WD repeat- and FYVE domain-containing protein 4,GO:0016021,integral to membrane,PF02138;PF00400;,,,,,,,,,WDFY4_HUMAN,Homo sapiens (Human), comp96605_c2_seq1,407,47.6658,0.60734019,9,22,,2.00E-38,Q8IZQ1,WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy),GO:0005545; GO:0003831; GO:0005737; GO:0019898; GO:0046872; GO:0005635,"1-phosphatidylinositol binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; cytoplasm; extrinsic to membrane; metal ion binding; nuclear envelope",PF02138;PF15787;PF01363;PF14844;,,,,,,,,,WDFY3_HUMAN,Homo sapiens (Human),aggrephagy [GO:0035973] comp96633_c2_seq1,300,42.3333,0.22907408,11,17,,1.00E-38,Q13163,Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5),Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5),GO:0005524; GO:0070375; GO:0000187; GO:0071499; GO:0005829; GO:0007507; GO:0046872; GO:0032088; GO:0043066; GO:0090051; GO:2000342; GO:0043154; GO:2001240; GO:0034115; GO:0045415; GO:0060761; GO:0000122; GO:0048011; GO:0005634; GO:0018108; GO:0030307; GO:0050679; GO:0045944; GO:0004672; GO:0004674; GO:0004713; GO:0005819,ATP binding; ERK5 cascade; activation of MAPK activity; cellular response to laminar fluid shear stress; cytosol; heart development; metal ion binding; negative regulation of NF-kappaB transcription factor activity; negative regulation of apoptotic process; negative regulation of cell migration involved in sprouting angiogenesis; negative regulation of chemokine (C-X-C motif) ligand 2 production; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of heterotypic cell-cell adhesion; negative regulation of interleukin-8 biosynthetic process; negative regulation of response to cytokine stimulus; negative regulation of transcription from RNA polymerase II promoter; neurotrophin TRK receptor signaling pathway; nucleus; peptidyl-tyrosine phosphorylation; positive regulation of cell growth; positive regulation of epithelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; spindle,PF00564;PF00069;,2.00E-18,CHOYP_MP2K5.1.1,,,,,,,MP2K5_HUMAN,Homo sapiens (Human),activation of MAPK activity [GO:0000187]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165] comp96634_c0_seq1,235,62.9787,1.04119532,0,4,,2.00E-16,P59962,NADH-quinone oxidoreductase subunit G (EC 1.6.99.5) (NADH dehydrogenase I subunit G) (NDH-1 subunit G),NADH-quinone oxidoreductase subunit G (EC 1.6.5.11) (NADH dehydrogenase I subunit G) (NDH-1 subunit G),GO:0051537; GO:0051539; GO:0042773; GO:0008137; GO:0009055; GO:0016020; GO:0030151; GO:0048038,"2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; ATP synthesis coupled electron transport; NADH dehydrogenase (ubiquinone) activity; electron carrier activity; membrane; molybdenum ion binding; quinone binding",PF00384;PF01568;PF10588;,,,,,,,,,NUOG_MYCBO,Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97),ATP synthesis coupled electron transport [GO:0042773] comp96659_c0_seq1,206,38.835,0.64689024,3,0,,2.00E-16,Q5U430,E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650),GO:0001701; GO:0016021; GO:0042048; GO:0007608; GO:0001967; GO:0006511; GO:0004842; GO:0008270,in utero embryonic development; integral to membrane; olfactory behavior; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity; zinc ion binding,PF02207;,,,,,,,,,UBR3_MOUSE,Mus musculus (Mouse),embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] comp96666_c1_seq1,240,35.8333,0.26425897,16,22,,5.00E-07,Q9BU70,Nef-associated protein 1 (EC 3.1.2.-) (Thioesterase NAP1),tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O),GO:0016787; GO:0019048,hydrolase activity; modulation by virus of host morphology or physiology,PF01980;,,,,,,,,,NAP1_HUMAN,Homo sapiens (Human),tRNA methylation [GO:0030488] comp96696_c0_seq1,512,35.1562,0.69744426,26,29,,,,,,,,,,,5.00E-14,ruditapes_c17805,,,,,,, comp96702_c1_seq1,206,41.2621,1.27494606,2,0,,,,,,,,,,,2.00E-32,ruditapes_c25079,,,,,,, comp96708_c0_seq1,246,63.0081,1.19385306,0,1,,5.00E-27,P54919,Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase),Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase),GO:0046872; GO:0004655; GO:0006782,metal ion binding; porphobilinogen synthase activity; protoporphyrinogen IX biosynthetic process,PF00490;,,,,,,,,,HEM2_STRCO,Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145),heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] comp96732_c0_seq1,575,48.1739,0.78244751,22,31,,2.00E-31,Q0P5W1,Vacuolar protein sorting-associated protein 8 homolog,Vacuolar protein sorting-associated protein 8 homolog,GO:0008270,zinc ion binding,PF12816;,6.00E-23,CHOYP_VPS8.1.1,7.00E-45,ruditapes_c26591,,,,,VPS8_MOUSE,Mus musculus (Mouse),endosomal vesicle fusion [GO:0034058] comp96764_c2_seq1,342,42.6901,0.7538526,9,0,,1.00E-29,Q1LXK4,Putative helicase mov-10-B.1 (EC 3.6.4.13),Putative helicase mov-10-B.1 (EC 3.6.4.13),GO:0005524; GO:0003723; GO:0000932; GO:0004386; GO:0035279,ATP binding; RNA binding; cytoplasmic mRNA processing body; helicase activity; mRNA cleavage involved in gene silencing by miRNA,,,,,,,,,,M10B1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA cleavage involved in gene silencing by miRNA [GO:0035279] comp96776_c1_seq1,824,42.1117,0.72476117,6,102,,2.00E-24,Q9NZ94,Neuroligin-3 (Gliotactin homolog),Neuroligin-3 (Gliotactin homolog),GO:0048675; GO:0050839; GO:0030054; GO:0009986; GO:0030139; GO:0060076; GO:0005887; GO:0042043; GO:0007158; GO:2000969; GO:2000463; GO:0051965; GO:0051968; GO:0097104; GO:0097105; GO:0004872; GO:0006898; GO:2000310; GO:0061001; GO:0060080; GO:1900271; GO:0002087; GO:2000331; GO:0060024; GO:0035176; GO:0008542,"axon extension; cell adhesion molecule binding; cell junction; cell surface; endocytic vesicle; excitatory synapse; integral to plasma membrane; neurexin family protein binding; neuron cell-cell adhesion; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; positive regulation of excitatory postsynaptic membrane potential; positive regulation of synapse assembly; positive regulation of synaptic transmission, glutamatergic; postsynaptic membrane assembly; presynaptic membrane assembly; receptor activity; receptor-mediated endocytosis; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of dendritic spine morphogenesis; regulation of inhibitory postsynaptic membrane potential; regulation of long-term synaptic potentiation; regulation of respiratory gaseous exchange by neurological system process; regulation of terminal button organization; rhythmic synaptic transmission; social behavior; visual learning",PF00135;,,,,,,,,,NLGN3_HUMAN,Homo sapiens (Human),"adult behavior [GO:0030534]; axon extension [GO:0048675]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; oligodendrocyte differentiation [GO:0048709]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of synaptic vesicle clustering [GO:2000809]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; receptor-mediated endocytosis [GO:0006898]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; regulation of terminal button organization [GO:2000331]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse organization [GO:0050808]; visual learning [GO:0008542]; vocalization behavior [GO:0071625]" comp96801_c0_seq1,243,63.786,1.05840965,0,2,,6.00E-50,Q6A8J1,Aspartate--tRNA ligase (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS),Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS),GO:0005524; GO:0004815; GO:0006422; GO:0005737; GO:0003676,ATP binding; aspartate-tRNA ligase activity; aspartyl-tRNA aminoacylation; cytoplasm; nucleic acid binding,PF02938;PF00152;PF01336;,,,,,,,,,SYD_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),tRNA aminoacylation for protein translation [GO:0006418] comp96819_c0_seq1,580,41.3793,0.73133085,1,86,,4.00E-45,Q5R941,Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase),Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase),GO:0005509; GO:0005788; GO:0003755; GO:0006457; GO:0000413,calcium ion binding; endoplasmic reticulum lumen; peptidyl-prolyl cis-trans isomerase activity; protein folding; protein peptidyl-prolyl isomerization,PF13499;PF00254;,2.00E-15,CHOYP_LOC659512.4.4,,,,,,,FKB14_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein folding [GO:0006457] comp96826_c0_seq1,215,44.186,0.38298701,4,0,,8.00E-07,Q09660,Probable cytochrome P450 CYP44 (EC 1.14.-.-),Probable cytochrome P450 CYP44 (EC 1.14.-.-),GO:0020037; GO:0005506; GO:0004497; GO:0016705,"heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",PF00067;,,,,,,,,,CC44_CAEEL,Caenorhabditis elegans, comp96899_c0_seq1,924,46.5368,0.43036651,39,51,,7.00E-38,P07314,Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain],Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain],GO:0007568; GO:0034599; GO:0005615; GO:0003840; GO:0006536; GO:0006750; GO:0006751; GO:0036374; GO:0005887; GO:0031179; GO:0032355; GO:0032496; GO:0034612,aging; cellular response to oxidative stress; extracellular space; gamma-glutamyltransferase activity; glutamate metabolic process; glutathione biosynthetic process; glutathione catabolic process; glutathione hydrolase activity; integral to plasma membrane; peptide modification; response to estradiol stimulus; response to lipopolysaccharide; response to tumor necrosis factor,PF01019;,,,,,,,,,GGT1_RAT,Rattus norvegicus (Rat),aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; peptide modification [GO:0031179]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; zymogen activation [GO:0031638] comp96919_c1_seq2,440,39.3182,0.53047588,14,19,,4.00E-31,Q96BD5,PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80),PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80),GO:0003677; GO:0007596; GO:0003682; GO:0016568; GO:0000118; GO:0000122; GO:0006355; GO:0001967; GO:0006351; GO:0008270,"DNA binding; blood coagulation; chromatin binding; chromatin modification; histone deacetylase complex; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; suckling behavior; transcription, DNA-dependent; zinc ion binding",PF00628;,,,,,,,,,PF21A_HUMAN,Homo sapiens (Human),"blood coagulation [GO:0007596]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp96930_c0_seq1,442,59.0498,1.04064427,0,101,,2.00E-25,Q9GT45,40S ribosomal protein S26,40S ribosomal protein S26,GO:0005840; GO:0003735; GO:0006412,ribosome; structural constituent of ribosome; translation,PF01283;,,,2.00E-11,ruditapes_lrc23197,,,,,RS26_ANOGA,Anopheles gambiae (African malaria mosquito),translation [GO:0006412] comp96946_c0_seq1,256,49.2188,0.38939988,12,23,,3.00E-20,Q68FK8,ATP-dependent RNA helicase A-like protein (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),ATP-dependent RNA helicase A-like protein (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II),GO:0005524; GO:0008026; GO:0070937; GO:0003677; GO:0003723; GO:0005634,ATP binding; ATP-dependent helicase activity; CRD-mediated mRNA stability complex; DNA binding; RNA binding; nucleus,PF00270;PF00035;PF04408;PF00271;PF07717;,7.00E-11,CHOYP_BRAFLDRAFT_124637.1.1,,,,,,,DHX9_XENLA,Xenopus laevis (African clawed frog), comp96955_c0_seq1,267,38.2022,0.41278977,0,13,,2.00E-17,Q8JZL0,Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI),Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN467_MOUSE,Mus musculus (Mouse),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp96971_c2_seq1,340,63.5294,1.14106521,0,15,,4.00E-17,Q1WSB8,Energy-coupling factor transporter ATP-binding protein EcfA1 (ECF transporter A component EcfA1) (EC 3.6.3.-),Energy-coupling factor transporter ATP-binding protein EcfA1 (ECF transporter A component EcfA1) (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; plasma membrane; transport,PF00005;,,,,,,,,,ECFA2_LACS1,Lactobacillus salivarius (strain UCC118),transport [GO:0006810] comp96978_c0_seq1,745,38.6577,0.57840771,7,22,,6.00E-58,Q503V3,UPF0454 protein C12orf49 homolog,UPF0454 protein C12orf49 homolog,GO:0005576,extracellular region,PF10218;,,,,,,,,,CL049_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp96978_c0_seq2,678,39.6755,0.56583456,0,0,,,,,,,,,9.00E-15,CHOYP_LOC100376246.1.1,,,,,,,,, comp96983_c0_seq1,650,35.8462,0.91513978,32,28,,3.00E-15,P09478,Acetylcholine receptor subunit alpha-like 1,Acetylcholine receptor subunit alpha-like 1 (Nicotinic acetylcholine receptor alpha 1),GO:0004889; GO:0005892; GO:0030054; GO:0045211; GO:0017085; GO:0007271,"acetylcholine-activated cation-selective channel activity; acetylcholine-gated channel complex; cell junction; postsynaptic membrane; response to insecticide; synaptic transmission, cholinergic",PF02931;PF02932;,4.00E-19,CHOYP_LOC100533250.1.2,,,,,,,ACH1_DROME,Drosophila melanogaster (Fruit fly),"cation transport [GO:0006812]; neuromuscular synaptic transmission [GO:0007274]; response to insecticide [GO:0017085]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" comp96995_c0_seq1,350,40.5714,0.8382158,10,22,,2.00E-17,P04323,Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00078;,,,,,,,,,POL3_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp97042_c0_seq2,274,44.8905,0.60274775,0,2,,6.00E-19,Q9FUM9,Homocysteine S-methyltransferase 2 (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase 2) (SMM:Hcy S-methyltransferase 2) (ZmHMT-2),Homocysteine S-methyltransferase 2 (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase 2) (SMM:Hcy S-methyltransferase 2) (ZmHMT-2),GO:0008898; GO:0046872; GO:0009086,homocysteine S-methyltransferase activity; metal ion binding; methionine biosynthetic process,PF02574;,,,,,,,,,HMT2_MAIZE,Zea mays (Maize),methionine biosynthetic process [GO:0009086] comp97051_c0_seq1,721,44.7989,0.60430567,13,80,,5.00E-12,Q9P0W5,Schwannomin-interacting protein 1 (SCHIP-1),Schwannomin-interacting protein 1 (SCHIP-1),GO:0005737,cytoplasm,PF10148;,,,,,,,,,SCHI1_HUMAN,Homo sapiens (Human), comp97070_c0_seq1,225,60.4444,0.96975719,1,7,,3.00E-14,O32333,Glucitol/sorbitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.69) (EII-Gut) (PTS system glucitol/sorbitol-specific EIIB component),PTS system glucitol/sorbitol-specific EIIB component (EC 2.7.1.198) (EII-Gut) (Enzyme II-Gut) (Glucitol/sorbitol-specific phosphotransferase enzyme IIB component),GO:0016021; GO:0016301; GO:0009401; GO:0005886; GO:0008982,integral to membrane; kinase activity; phosphoenolpyruvate-dependent sugar phosphotransferase system; plasma membrane; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity,PF07663;PF03612;,,,,,,,,,PTHB_CLOB8,Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum),phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401] comp97072_c0_seq1,877,38.4265,0.49552093,71,94,,4.00E-15,A7Z056,Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20),Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20),GO:0005813; GO:0004197; GO:0006897; GO:0048471; GO:0071108; GO:0070536; GO:0008277; GO:0004221; GO:0006511; GO:0008270,centrosome; cysteine-type endopeptidase activity; endocytosis; perinuclear region of cytoplasm; protein K48-linked deubiquitination; protein K63-linked deubiquitination; regulation of G-protein coupled receptor protein signaling pathway; ubiquitin thiolesterase activity; ubiquitin-dependent protein catabolic process; zinc ion binding,PF06337;PF00443;PF02148;,,,,,,,,,UBP20_BOVIN,Bos taurus (Bovine),endocytosis [GO:0006897]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511] comp97080_c0_seq1,273,34.7985,0.97423529,8,22,,,,,,,,,,,7.00E-60,ruditapes_c12318,,,,,,, comp97106_c0_seq1,369,42.2764,0.42634058,4,14,,1.00E-27,Q8TBZ3,WD repeat-containing protein 20 (Protein DMR),WD repeat-containing protein 20 (Protein DMR),,,PF00400;,,,,,,,,,WDR20_HUMAN,Homo sapiens (Human), comp97109_c0_seq1,858,41.958,0.66436879,18,67,,7.00E-116,Q8BUB4,WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain-containing protein 2),WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2),GO:0046872,metal ion binding,PF01363;PF00400;,1.00E-129,CHOYP_BRAFLDRAFT_70886.1.1,,,,,,,WDFY2_MOUSE,Mus musculus (Mouse),positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934] comp97109_c0_seq2,241,42.7386,0.39190958,0,0,,6.00E-08,P78706,Transcriptional repressor rco-1,Transcriptional repressor rco-1,GO:0048315; GO:0006355; GO:0030435; GO:0006351,"conidium formation; regulation of transcription, DNA-dependent; sporulation resulting in formation of a cellular spore; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,RCO1_NEUCR,Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987),"conidium formation [GO:0048315]; sporulation resulting in formation of a cellular spore [GO:0030435]; transcription, DNA-templated [GO:0006351]" comp97125_c0_seq1,383,46.7363,0.62416029,14,20,,1.00E-59,O95405,Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation),Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation),GO:0005545; GO:0007183; GO:0007184; GO:0031901; GO:0006897; GO:0046872; GO:0030512; GO:0008236; GO:0007179,1-phosphatidylinositol binding; SMAD protein complex assembly; SMAD protein import into nucleus; early endosome membrane; endocytosis; metal ion binding; negative regulation of transforming growth factor beta receptor signaling pathway; serine-type peptidase activity; transforming growth factor beta receptor signaling pathway,PF11979;PF01363;PF11409;,4.00E-35,CHOYP_LOC575625.2.2,,,,,,,ZFYV9_HUMAN,Homo sapiens (Human),endocytosis [GO:0006897]; SMAD protein complex assembly [GO:0007183]; SMAD protein import into nucleus [GO:0007184]; transforming growth factor beta receptor signaling pathway [GO:0007179] comp9712_c0_seq1,224,42.8571,0.79824207,7,0,,7.00E-11,Q8C456,WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein),WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein),GO:0035085; GO:0060271; GO:0005856; GO:0005886; GO:0016476; GO:0032880; GO:0032185,cilium axoneme; cilium morphogenesis; cytoskeleton; plasma membrane; regulation of embryonic cell shape; regulation of protein localization; septin cytoskeleton organization,PF11768;,,,,,,,,,FRITZ_MOUSE,Mus musculus (Mouse),auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cardiovascular system development [GO:0072358]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cilium organization [GO:0044782]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; glomerular visceral epithelial cell migration [GO:0090521]; kidney development [GO:0001822]; nervous system development [GO:0007399]; palate development [GO:0060021]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224] comp97130_c0_seq1,811,42.5401,0.55438058,23,38,,3.00E-79,Q9JI90,E3 ubiquitin-protein ligase RNF14 (EC 6.3.2.-) (Androgen receptor-associated protein 54) (Protein Triad2) (RING finger protein 14),E3 ubiquitin-protein ligase RNF14 (EC 6.3.2.-) (Androgen receptor-associated protein 54) (Protein Triad2) (RING finger protein 14),GO:0050681; GO:0005737; GO:0005634; GO:0045893; GO:0060765; GO:0032355; GO:0019787; GO:0006351; GO:0008270,"androgen receptor binding; cytoplasm; nucleus; positive regulation of transcription, DNA-dependent; regulation of androgen receptor signaling pathway; response to estradiol stimulus; small conjugating protein ligase activity; transcription, DNA-dependent; zinc ion binding",PF01485;PF05773;,7.00E-43,CHOYP_LOC100375328.1.1,,,,,,,RNF14_MOUSE,Mus musculus (Mouse),"positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription, DNA-templated [GO:0045893]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]" comp97133_c0_seq1,331,40.7855,0.73354624,8,29,,2.00E-15,P39413,Adult enhancer factor 1 (AEF-1),Adult enhancer factor 1 (AEF-1),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,AEF1_DROME,Drosophila melanogaster (Fruit fly),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp97153_c0_seq1,535,45.7944,0.96634953,14,59,,1.00E-29,Q60934,"Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)","Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)",GO:0030534; GO:0048266; GO:0030054; GO:0030425; GO:0005234; GO:0015277; GO:0032983; GO:0051967; GO:0014054; GO:0032230; GO:0045211; GO:0042734; GO:0060079; GO:0060080; GO:0048169; GO:0048172; GO:0035249,"adult behavior; behavioral response to pain; cell junction; dendrite; extracellular-glutamate-gated ion channel activity; kainate selective glutamate receptor activity; kainate selective glutamate receptor complex; negative regulation of synaptic transmission, glutamatergic; positive regulation of gamma-aminobutyric acid secretion; positive regulation of synaptic transmission, GABAergic; postsynaptic membrane; presynaptic membrane; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential; regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; synaptic transmission, glutamatergic",PF01094;PF00060;PF10613;,,,,,,,,,GRIK1_MOUSE,Mus musculus (Mouse),"adult behavior [GO:0030534]; behavioral response to pain [GO:0048266]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; membrane depolarization [GO:0051899]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]" comp97163_c0_seq1,625,47.2,0.72635478,10,42,,2.00E-77,Q16832,"Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)","Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)",GO:0005524; GO:0031214; GO:0007155; GO:0035988; GO:0005518; GO:0030199; GO:0003416; GO:0005887; GO:0001503; GO:0090091; GO:0010763; GO:0048146; GO:0045669; GO:0045860; GO:0051091; GO:0046777; GO:0038062; GO:0030500,ATP binding; biomineral tissue development; cell adhesion; chondrocyte proliferation; collagen binding; collagen fibril organization; endochondral bone growth; integral to plasma membrane; ossification; positive regulation of extracellular matrix disassembly; positive regulation of fibroblast migration; positive regulation of fibroblast proliferation; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; positive regulation of sequence-specific DNA binding transcription factor activity; protein autophosphorylation; protein tyrosine kinase collagen receptor activity; regulation of bone mineralization,PF00754;PF07714;,6.00E-112,CHOYP_LOC100903889.1.1,,,,,,,DDR2_HUMAN,Homo sapiens (Human),biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; signal transduction [GO:0007165] comp97163_c1_seq1,335,42.9851,0.95455396,2,28,,9.00E-24,P20806,Protein sevenless (EC 2.7.10.1),Protein sevenless (EC 2.7.10.1),GO:0005524; GO:0016021; GO:0018108; GO:0005886; GO:0004714; GO:0007169; GO:0007601,ATP binding; integral to membrane; peptidyl-tyrosine phosphorylation; plasma membrane; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway; visual perception,PF00041;PF07714;,,,,,,,,,7LESS_DROVI,Drosophila virilis (Fruit fly),transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; visual perception [GO:0007601] comp97164_c0_seq1,799,43.179,0.42111239,50,47,,9.00E-40,Q6PR54,Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1),Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1),GO:0007049; GO:0000781; GO:0005737; GO:0001939; GO:0001940; GO:0006974; GO:0005819; GO:0019827; GO:0000723,"cell cycle; chromosome, telomeric region; cytoplasm; female pronucleus; male pronucleus; response to DNA damage stimulus; spindle; stem cell maintenance; telomere maintenance",PF12231;,,,,,,,,,RIF1_MOUSE,Mus musculus (Mouse),cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; stem cell population maintenance [GO:0019827] comp97168_c1_seq1,235,28.5106,1.10696188,6,4,,5.00E-08,Q86VZ4,Low-density lipoprotein receptor-related protein 11 (LRP-11),Low-density lipoprotein receptor-related protein 11 (LRP-11),GO:0016021,integral to membrane,PF00057;PF07502;,,,,,,,,,LRP11_HUMAN,Homo sapiens (Human),multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414] comp97181_c0_seq1,1437,39.3876,0.51247352,41,180,,4.00E-60,Q4G055,RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3),RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3),GO:0003723; GO:0005689; GO:0000166,RNA binding; U12-type spliceosomal complex; nucleotide binding,PF00076;,,,,,,,,,RBM40_RAT,Rattus norvegicus (Rat),"developmental process [GO:0032502]; mRNA splicing, via spliceosome [GO:0000398]" comp97184_c0_seq1,225,40.4444,0.81632159,6,0,,2.00E-06,Q8R179,Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4),Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4),,,PF07707;PF00651;,,,,,,,,,KBTB4_MOUSE,Mus musculus (Mouse), comp97195_c0_seq1,427,48.7119,0.63407755,6,40,,2.00E-88,Q17LW0,Myosin-VIIa (Protein crinkled),Myosin-VIIa (Protein crinkled),GO:0005524; GO:0030048; GO:0030898; GO:0048800; GO:0008407; GO:0005737; GO:0035317; GO:0003774; GO:0016459; GO:0032027; GO:0007605,ATP binding; actin filament-based movement; actin-dependent ATPase activity; antennal morphogenesis; chaeta morphogenesis; cytoplasm; imaginal disc-derived wing hair organization; motor activity; myosin complex; myosin light chain binding; sensory perception of sound,PF00373;PF00612;PF00063;PF00784;,5.00E-98,CHOYP_MYO7A.1.3,,,,,,,MYO7A_AEDAE,Aedes aegypti (Yellowfever mosquito) (Culex aegypti),actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] comp97196_c0_seq1,585,39.3162,0.85646404,3,71,,3.00E-10,Q9ZPX1,ADP-ribosylation factor-like protein 2 (Protein ARF-like 2) (Protein HALLIMASCH) (Protein TITAN 5),ADP-ribosylation factor-like protein 2 (Protein ARF-like 2) (Protein HALLIMASCH) (Protein TITAN 5),GO:0005525; GO:0005737; GO:0009793; GO:0009558; GO:0009960; GO:0007264; GO:0007021,GTP binding; cytoplasm; embryo development ending in seed dormancy; embryo sac cellularization; endosperm development; small GTPase mediated signal transduction; tubulin complex assembly,PF00025;,,,,,,,,,ARF5_ARATH,Arabidopsis thaliana (Mouse-ear cress),embryo development ending in seed dormancy [GO:0009793]; embryo sac cellularization [GO:0009558]; endosperm development [GO:0009960]; small GTPase mediated signal transduction [GO:0007264]; tubulin complex assembly [GO:0007021] comp97201_c1_seq1,544,41.9118,0.63298704,9,117,,2.00E-52,Q7JW12,Thioredoxin-related transmembrane protein 2 homolog (Thioredoxin domain-containing protein 14 homolog),Thioredoxin-related transmembrane protein 2 homolog (Thioredoxin domain-containing protein 14 homolog),GO:0045454; GO:0016021,cell redox homeostasis; integral to membrane,PF00085;,9.00E-14,CHOYP_LOC100650138.1.1,,,,,,,TMX2_DROME,Drosophila melanogaster (Fruit fly),cell redox homeostasis [GO:0045454] comp97202_c1_seq1,203,44.8276,0.59189057,0,15,,7.00E-13,O64411,Polyamine oxidase (EC 1.5.3.14) (EC 1.5.3.15),Polyamine oxidase (EC 1.5.3.14) (EC 1.5.3.15),GO:0052898; GO:0052893; GO:0052897; GO:0052896; GO:0052900,"N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity; spermidine oxidase (propane-1,3-diamine-forming) activity; spermine oxidase (propane-1,3-diamine-forming) activity",PF01593;,,,,,,,,,PAO_MAIZE,Zea mays (Maize), comp97207_c0_seq1,587,47.5298,0.55840618,16,36,,3.00E-55,Q7TNF8,Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIMS-binding protein 1) (RIM-BP1),Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1),GO:0005739,mitochondrion,PF07653;PF14604;,1.00E-38,CHOYP_RIMB2.5.5,,,,,,,RIMB1_MOUSE,Mus musculus (Mouse), comp97208_c0_seq1,549,41.5301,0.29854317,11,35,,9.00E-17,P28662,Brain protein I3,Brain protein I3,GO:0016021,integral to membrane,PF10164;,9.00E-14,CHOYP_LOC100375457.1.1,,,,,,,BRI3_MOUSE,Mus musculus (Mouse), comp97210_c0_seq1,885,41.6949,0.6190542,22,46,,5.00E-53,Q80TF4,Kelch-like protein 13 (BTB and kelch domain-containing protein 2),Kelch-like protein 13 (BTB and kelch domain-containing protein 2),GO:0031463; GO:0000910; GO:0007067; GO:0016567,Cul3-RING ubiquitin ligase complex; cytokinesis; mitosis; protein ubiquitination,PF07707;PF00651;PF01344;,1.00E-21,CHOYP_BRAFLDRAFT_202115.1.1,,,,,,,KLH13_MOUSE,Mus musculus (Mouse),cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567] comp97210_c1_seq1,387,49.354,0.69674988,4,18,,2.00E-27,Q53HC5,Kelch-like protein 26,Kelch-like protein 26,,,PF07707;PF00651;PF01344;,,,,,,,,,KLH26_HUMAN,Homo sapiens (Human),protein ubiquitination [GO:0016567] comp97213_c1_seq2,255,45.8824,0.456335,2,0,,4.00E-24,Q13308,Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7),Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7),GO:0005524; GO:0031532; GO:0003401; GO:0060070; GO:0007155; GO:0016477; GO:0005911; GO:0071300; GO:0090103; GO:0060026; GO:0045198; GO:0001736; GO:0005887; GO:0060484; GO:0001843; GO:0090179; GO:0010976; GO:0004714; GO:0042060,ATP binding; actin cytoskeleton reorganization; axis elongation; canonical Wnt receptor signaling pathway; cell adhesion; cell migration; cell-cell junction; cellular response to retinoic acid; cochlea morphogenesis; convergent extension; establishment of epithelial cell apical/basal polarity; establishment of planar polarity; integral to plasma membrane; lung-associated mesenchyme development; neural tube closure; planar cell polarity pathway involved in neural tube closure; positive regulation of neuron projection development; transmembrane receptor protein tyrosine kinase activity; wound healing,PF07679;PF07714;,,,,,,,,,PTK7_HUMAN,Homo sapiens (Human),actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; canonical Wnt signaling pathway [GO:0060070]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; lung-associated mesenchyme development [GO:0060484]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of neuron projection development [GO:0010976]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] comp97224_c0_seq1,216,42.5926,0.6153251,2,6,,8.00E-28,B7LQ82,UPF0061 protein YdiU,UPF0061 protein YdiU,,,PF02696;,3.00E-39,CHOYP_LOC100371716.1.1,,,,,,,YDIU_ESCF3,Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73), comp97225_c0_seq1,594,34.6801,0.53374018,20,52,,2.00E-06,Q5T0B9,Zinc finger protein 362,Zinc finger protein 362,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;,,,,,,,,,ZN362_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp97239_c0_seq1,220,43.1818,0.53279789,6,0,,2.00E-10,Q5XIY8,PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein),GO:0006281; GO:0005634; GO:0006355; GO:0006351,"DNA repair; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00533;PF16589;PF12738;,2.00E-11,CHOYP_PAXI1.3.4,,,,,,,PAXI1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),"DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp97261_c1_seq1,844,42.1801,0.4004998,25,36,,7.00E-09,Q4V885,Collectin-12 (Collectin placenta protein 1) (CL-P1) (Nurse cell scavenger receptor 2),Collectin-12 (Collectin placenta protein 1) (CL-P1) (Nurse cell scavenger receptor 2),GO:0030246; GO:0005581; GO:0006955; GO:0016021; GO:0030169; GO:0046872; GO:0006910; GO:0008329,"carbohydrate binding; collagen; immune response; integral to membrane; low-density lipoprotein particle binding; metal ion binding; phagocytosis, recognition; signaling pattern recognition receptor activity",PF01391;PF00059;,,,,,,,,,COL12_RAT,Rattus norvegicus (Rat),"cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]" comp97271_c0_seq1,329,65.0456,0.99469004,0,9,,1.00E-13,B1VSG4,GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I),GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I),GO:0035998; GO:0005525; GO:0003934; GO:0005737; GO:0006730; GO:0046654; GO:0008270,"7,8-dihydroneopterin 3'-triphosphate biosynthetic process; GTP binding; GTP cyclohydrolase I activity; cytoplasm; one-carbon metabolic process; tetrahydrofolate biosynthetic process; zinc ion binding",PF01227;,,,,,,,,,GCH1_STRGG,Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350),"7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]" comp97276_c0_seq1,524,46.374,0.3953869,8,30,,1.00E-56,Q9UKN7,Unconventional myosin-XV (Unconventional myosin-15),Unconventional myosin-XV (Unconventional myosin-15),GO:0005524; GO:0005737; GO:0042472; GO:0007626; GO:0003774; GO:0016459; GO:0007605; GO:0032420,ATP binding; cytoplasm; inner ear morphogenesis; locomotory behavior; motor activity; myosin complex; sensory perception of sound; stereocilium,PF00373;PF00612;PF00063;PF00784;PF07653;,1.00E-101,CHOYP_MYO15.1.1,7.00E-13,ruditapes_c23012,,,,,MYO15_HUMAN,Homo sapiens (Human),inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] comp97291_c0_seq1,214,40.6542,0.70262972,1,11,,,,,,,,,,,7.00E-14,ruditapes2_c2237,,,,,,, comp97296_c0_seq1,487,41.4784,0.57974702,20,44,,7.00E-29,Q86UF1,Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane),Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane),GO:0016021,integral to membrane,PF00335;,,,,,,,,,TSN33_HUMAN,Homo sapiens (Human),cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604] comp97300_c0_seq3,329,43.465,0.26107836,0,0,,,,,,,,,5.00E-27,CHOYP_TRIADDRAFT_57945.2.3,,,,,,,,, comp97302_c0_seq1,315,40.9524,0.79437704,2,38,,5.00E-33,Q2XWK0,Synaptic vesicle 2-related protein (SV2-related protein),Synaptic vesicle 2-related protein (SV2-related protein),GO:0030054; GO:0016021; GO:0030672; GO:0022857,cell junction; integral to membrane; synaptic vesicle membrane; transmembrane transporter activity,PF07690;PF00083;,3.00E-30,CHOYP_LOC100375275.1.1,,,,,,,SVOP_XENLA,Xenopus laevis (African clawed frog), comp97303_c1_seq1,334,44.9102,0.11919694,8,8,,1.00E-15,Q4LDE5,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp97315_c0_seq1,517,45.8414,0.53081739,20,34,,9.00E-45,A3KPP4,Solute carrier family 25 member 35,Solute carrier family 25 member 35,GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,3.00E-32,CHOYP_LOC577507.1.1,,,,,,,S2535_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),translation [GO:0006412]; transport [GO:0006810] comp97315_c1_seq1,837,39.4265,0.35181914,28,21,,2.00E-56,A3KPP4,Solute carrier family 25 member 35,Solute carrier family 25 member 35,GO:0016021; GO:0005743; GO:0006810,integral to membrane; mitochondrial inner membrane; transport,PF00153;,,,,,,,,,S2535_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),translation [GO:0006412]; transport [GO:0006810] comp97316_c0_seq1,519,42.9672,1.06122843,7,65,,4.00E-48,Q60716,"Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)","Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)",GO:0031418; GO:0005788; GO:0005506; GO:0016702; GO:0018401; GO:0004656,"L-ascorbic acid binding; endoplasmic reticulum lumen; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; procollagen-proline 4-dioxygenase activity",PF13640;PF08336;,,,,,,,,,P4HA2_MOUSE,Mus musculus (Mouse),peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] comp97332_c0_seq1,278,44.6043,1.09901632,1,24,,5.00E-26,Q26636,Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain],GO:0030154; GO:0008234; GO:0005764; GO:0007275; GO:0006508,cell differentiation; cysteine-type peptidase activity; lysosome; multicellular organismal development; proteolysis,PF08246;PF00112;,,,,,,,,,CATL_SARPE,Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina),cell differentiation [GO:0030154]; multicellular organism development [GO:0007275] comp97335_c3_seq1,771,42.2827,0.31992218,20,24,,4.00E-42,O14981,TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172),GO:0005524; GO:0003677; GO:0004386; GO:0045892; GO:0005634; GO:0003700,"ATP binding; DNA binding; helicase activity; negative regulation of transcription, DNA-dependent; nucleus; sequence-specific DNA binding transcription factor activity",PF12054;PF00271;PF00176;,6.00E-18,CHOYP_BTAF1.2.2,,,,,,,BTAF1_HUMAN,Homo sapiens (Human),"negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]" comp97381_c0_seq1,230,44.3478,0.58334436,1,13,,4.00E-26,P35992,Tyrosine-protein phosphatase 10D (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D),Tyrosine-protein phosphatase 10D (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D),GO:0045177; GO:0030424; GO:0007417; GO:0016021; GO:0007616; GO:0008045; GO:0007424; GO:0005886; GO:0005001,apical part of cell; axon; central nervous system development; integral to membrane; long-term memory; motor neuron axon guidance; open tracheal system development; plasma membrane; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF00102;,,,,,,,,,PTP10_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470] comp97383_c0_seq1,319,45.768,0.40395937,6,10,,1.00E-18,Q17RS7,Flap endonuclease GEN homolog 1 (EC 3.1.-.-),Flap endonuclease GEN homolog 1 (EC 3.1.-.-),GO:0003677; GO:0006281; GO:0004519; GO:0046872; GO:0090305; GO:0005634,DNA binding; DNA repair; endonuclease activity; metal ion binding; nucleic acid phosphodiester bond hydrolysis; nucleus,PF00867;PF00752;,,,,,,,,,GEN_HUMAN,Homo sapiens (Human),double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] comp97395_c2_seq1,452,43.1416,0.64814317,10,34,,1.00E-27,Q3UHC7,Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein),Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein),GO:0007252; GO:0005099; GO:0017124; GO:0000185; GO:0001525; GO:0007049; GO:0021814; GO:0044257; GO:0071347; GO:0071222; GO:0071356; GO:0035924; GO:0044300; GO:0044301; GO:0030425; GO:0030139; GO:0006954; GO:0045087; GO:0070059; GO:0031235; GO:0021819; GO:0070373; GO:0070317; GO:0043124; GO:0043407; GO:0032088; GO:0034261; GO:0046580; GO:0016525; GO:0035414; GO:2000599; GO:0010596; GO:0050680; GO:0010719; GO:0048147; GO:0043553; GO:0014067; GO:0034144; GO:0000122; GO:0030948; GO:1900747; GO:0048812; GO:0032809; GO:1990032; GO:0036312; GO:0032266; GO:0070273; GO:0046330; GO:0043507; GO:0043065; GO:2001235; GO:0071158; GO:1900006; GO:0050679; GO:2001224; GO:1901800; GO:0090129; GO:0045944; GO:0032403; GO:0032312; GO:0040008; GO:1900744; GO:0043254; GO:0006986; GO:0035148; GO:0036324,I-kappaB phosphorylation; Ras GTPase activator activity; SH3 domain binding; activation of MAPKKK activity; angiogenesis; cell cycle; cell motility involved in cerebral cortex radial glia guided migration; cellular protein catabolic process; cellular response to interleukin-1; cellular response to lipopolysaccharide; cellular response to tumor necrosis factor; cellular response to vascular endothelial growth factor stimulus; cerebellar mossy fiber; climbing fiber; dendrite; endocytic vesicle; inflammatory response; innate immune response; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; intrinsic to internal side of plasma membrane; layer formation in cerebral cortex; negative regulation of ERK1 and ERK2 cascade; negative regulation of G0 to G1 transition; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of MAP kinase activity; negative regulation of NF-kappaB transcription factor activity; negative regulation of Ras GTPase activity; negative regulation of Ras protein signal transduction; negative regulation of angiogenesis; negative regulation of catenin import into nucleus; negative regulation of cyclin catabolic process; negative regulation of endothelial cell migration; negative regulation of epithelial cell proliferation; negative regulation of epithelial to mesenchymal transition; negative regulation of fibroblast proliferation; negative regulation of phosphatidylinositol 3-kinase activity; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of toll-like receptor 4 signaling pathway; negative regulation of transcription from RNA polymerase II promoter; negative regulation of vascular endothelial growth factor receptor signaling pathway; negative regulation of vascular endothelial growth factor signaling pathway; neuron projection morphogenesis; neuronal cell body membrane; parallel fiber; phosphatidylinositol 3-kinase regulatory subunit binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4-phosphate binding; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of apoptotic process; positive regulation of apoptotic signaling pathway; positive regulation of cell cycle arrest; positive regulation of dendrite development; positive regulation of epithelial cell proliferation; positive regulation of neuron migration; positive regulation of proteasomal protein catabolic process; positive regulation of synapse maturation; positive regulation of transcription from RNA polymerase II promoter; protein complex binding; regulation of ARF GTPase activity; regulation of growth; regulation of p38MAPK cascade; regulation of protein complex assembly; response to unfolded protein; tube formation; vascular endothelial growth factor receptor-2 signaling pathway,PF00168;PF12004;PF00616;,3.00E-38,CHOYP_NGAP.1.2,,,,,,,DAB2P_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of MAPKKK activity [GO:0000185]; angiogenesis [GO:0001525]; cell cycle [GO:0007049]; cell motility involved in cerebral cortex radial glia guided migration [GO:0021814]; cellular protein catabolic process [GO:0044257]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; layer formation in cerebral cortex [GO:0021819]; negative regulation of angiogenesis [GO:0016525]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of catenin import into nucleus [GO:0035414]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin catabolic process [GO:2000599]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of GTPase activity [GO:0034260]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; neuron projection morphogenesis [GO:0048812]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of synapse maturation [GO:0090129]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; reelin-mediated signaling pathway [GO:0038026]; regulation of growth [GO:0040008]; regulation of GTPase activity [GO:0043087]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein complex assembly [GO:0043254]; regulation of protein heterodimerization activity [GO:0043497]; response to unfolded protein [GO:0006986]; tube formation [GO:0035148]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]" comp97401_c0_seq1,545,42.5688,0.44754249,18,23,,3.00E-17,O43822,Protein C21orf2 (C21orf-HUMF09G8.5) (YF5/A2),Protein C21orf2 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2),GO:0030030; GO:0005737; GO:0007010; GO:0005886; GO:0008360,cell projection organization; cytoplasm; cytoskeleton organization; plasma membrane; regulation of cell shape,,,,,,,,,,CU002_HUMAN,Homo sapiens (Human),cilium morphogenesis [GO:0060271]; cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; smoothened signaling pathway [GO:0007224] comp97404_c0_seq1,287,46.6899,0.65934866,5,9,,3.00E-21,Q8IWE5,Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2) (Salmonella-induced filaments A and kinesin-interacting protein) (SifA and kinesin-interacting protein),Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2) (Salmonella-induced filaments A and kinesin-interacting protein) (SifA and kinesin-interacting protein),GO:0007030; GO:0005737; GO:0019894; GO:0005543,Golgi organization; cytoplasm; kinesin binding; phospholipid binding,PF00169;PF02759;,,,,,,,,,PKHM2_HUMAN,Homo sapiens (Human),Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880] comp97405_c0_seq2,321,39.8754,1.42374263,0,0,,,,,,,,,2.00E-38,CHOYP_contig_012322,,,,,,,,, comp97405_c0_seq4,277,41.8773,1.32857168,7,0,,,,,,,,,9.00E-42,CHOYP_contig_046226,1.00E-32,ruditapes2_c1704,,,,,,, comp97405_c1_seq1,250,44,1.5446401,8,1,,,,,,,,,,,1.00E-18,ruditapes2_c2949,,,,,,, comp97408_c0_seq1,677,43.87,0.46767324,21,9,,3.00E-36,Q9H4I3,TraB domain-containing protein (Protein TTG2),TraB domain-containing protein (Protein TTG2),,,PF01963;,,,,,,,,,TRABD_HUMAN,Homo sapiens (Human), comp97411_c2_seq1,201,47.2637,0.62678856,2,0,,2.00E-25,A2VCW9,"Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]","Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]",GO:0033512; GO:0005739; GO:0047131; GO:0047130,"L-lysine catabolic process to acetyl-CoA via saccharopine; mitochondrion; saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity; saccharopine dehydrogenase (NADP+, L-lysine-forming) activity",PF05222;PF16653;PF03435;,1.00E-24,CHOYP_LOC100123521.2.2,,,,,,,AASS_RAT,Rattus norvegicus (Rat),L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512] comp97426_c0_seq1,220,40,0.57195799,5,5,,1.00E-19,Q9W5D0,Uncharacterized protein CG42248,Uncharacterized protein CG43867,GO:0005856; GO:0005543,cytoskeleton; phospholipid binding,PF00373;PF00784;PF00169;,,,,,,,,,Y34F_DROME,Drosophila melanogaster (Fruit fly), comp97431_c0_seq1,376,39.0957,0.28745914,12,34,,1.00E-21,Q2YDS1,DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2),DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2),GO:0003677; GO:0006281; GO:0005634; GO:0016567,DNA binding; DNA repair; nucleus; protein ubiquitination,PF00400;,,,,,,,,,DDB2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA repair [GO:0006281]; protein ubiquitination [GO:0016567] comp97436_c0_seq1,520,41.9231,0.74705067,18,22,,1.00E-09,O75051,Plexin-A2 (Semaphorin receptor OCT),Plexin-A2 (Semaphorin receptor OCT),GO:0007411; GO:0051642; GO:0021935; GO:0005887; GO:0005622; GO:0060174; GO:0021915; GO:0060037; GO:0030334; GO:0017154; GO:0002116; GO:0001756,axon guidance; centrosome localization; cerebellar granule cell precursor tangential migration; integral to plasma membrane; intracellular; limb bud formation; neural tube development; pharyngeal system development; regulation of cell migration; semaphorin receptor activity; semaphorin receptor complex; somitogenesis,PF08337;PF01437;PF01403;PF01833;,,,,,,,,,PLXA2_HUMAN,Homo sapiens (Human),branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] comp97450_c0_seq2,344,48.5465,0.34668682,0,0,,1.00E-24,Q9UKA1,F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein),F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein),GO:0019005; GO:0031146; GO:0005506; GO:0055072; GO:0048471; GO:0004842,SCF ubiquitin ligase complex; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; iron ion binding; iron ion homeostasis; perinuclear region of cytoplasm; ubiquitin-protein ligase activity,PF12937;PF01814;PF13516;,,,,,,,,,FBXL5_HUMAN,Homo sapiens (Human),iron ion homeostasis [GO:0055072]; positive regulation of cellular protein catabolic process [GO:1903364]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] comp97455_c0_seq1,240,42.0833,0.66945607,1,12,,2.00E-13,Q6IV72,Zinc finger protein 425,Zinc finger protein 425,GO:0003677; GO:0005737; GO:0046872; GO:0045892; GO:0005634; GO:0006351,"DNA binding; cytoplasm; metal ion binding; negative regulation of transcription, DNA-dependent; nucleus; transcription, DNA-dependent",PF01352;PF00096;PF13912;,,,,,,,,,ZN425_HUMAN,Homo sapiens (Human),"negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]" comp97470_c0_seq1,1144,41.8706,0.66312792,76,0,,1.00E-85,Q6YHK3,CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109),GO:0031225; GO:0005615; GO:0010951; GO:0005886; GO:0004867,anchored to membrane; extracellular space; negative regulation of endopeptidase activity; plasma membrane; serine-type endopeptidase inhibitor activity,PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;,3.00E-23,CHOYP_TRIADDRAFT_55768.1.2,,,,,,,CD109_HUMAN,Homo sapiens (Human),hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616] comp97472_c0_seq1,771,43.7095,0.79525567,0,9,,1.00E-106,Q9QX73,Rho guanine nucleotide exchange factor 9 (Collybistin) (Rac/Cdc42 guanine nucleotide exchange factor 9),Rho guanine nucleotide exchange factor 9 (Collybistin) (Rac/Cdc42 guanine nucleotide exchange factor 9),GO:0005089; GO:0005938; GO:0005543; GO:0043113; GO:0035023,Rho guanyl-nucleotide exchange factor activity; cell cortex; phospholipid binding; receptor clustering; regulation of Rho protein signal transduction,PF00169;PF00621;PF00018;,,,,,,,,,ARHG9_RAT,Rattus norvegicus (Rat),receptor clustering [GO:0043113]; regulation of Rho protein signal transduction [GO:0035023] comp97472_c0_seq2,727,44.4292,0.7300793,0,0,,3.00E-06,A6QNS3,Active breakpoint cluster region-related protein,Active breakpoint cluster region-related protein,GO:0005096; GO:0005089; GO:0005622; GO:0035556; GO:0005543; GO:0043547; GO:0035023,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; intracellular; intracellular signal transduction; phospholipid binding; positive regulation of GTPase activity; regulation of Rho protein signal transduction,PF00168;PF00169;PF00620;PF00621;,2.00E-54,CHOYP_ISCW_ISCW011606.1.2,,,,,,,ABR_BOVIN,Bos taurus (Bovine),actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phagocytosis [GO:0050766]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496] comp97504_c0_seq1,267,50.1873,0.48288966,19,21,,1.00E-30,Q8R3C6,Probable RNA-binding protein 19 (RNA-binding motif protein 19),Probable RNA-binding protein 19 (RNA-binding motif protein 19),GO:0003723; GO:0005694; GO:0005737; GO:0007275; GO:0005730; GO:0005654; GO:0000166; GO:0040019,RNA binding; chromosome; cytoplasm; multicellular organismal development; nucleolus; nucleoplasm; nucleotide binding; positive regulation of embryonic development,PF00076;,4.00E-20,CHOYP_RBM19.1.2,,,,,,,RBM19_MOUSE,Mus musculus (Mouse),multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019] comp97516_c0_seq1,512,41.9922,1.12048304,35,15,,3.00E-36,P97524,"Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)","Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)",GO:0005524; GO:0005788; GO:0005789; GO:0005779; GO:0004467; GO:0031957,ATP binding; endoplasmic reticulum lumen; endoplasmic reticulum membrane; integral to peroxisomal membrane; long-chain fatty acid-CoA ligase activity; very long-chain fatty acid-CoA ligase activity,PF00501;PF13193;,1.00E-17,CHOYP_SLC27A2.1.1,,,,,,,S27A2_RAT,Rattus norvegicus (Rat),fatty acid transport [GO:0015908]; long-chain fatty acid metabolic process [GO:0001676] comp97519_c0_seq1,242,41.7355,0.19612926,1,9,,2.00E-08,Q2KIL7,R3H domain-containing protein 4,R3H domain-containing protein 4,GO:0003676; GO:0005634,nucleic acid binding; nucleus,PF01424;PF13902;,,,,,,,,,R3HD4_BOVIN,Bos taurus (Bovine), comp97526_c0_seq1,439,40.5467,0.38928412,6,30,,5.00E-10,A0JNW5,UHRF1-binding protein 1-like,UHRF1-binding protein 1-like,,,PF12624;,,,,,,,,,UH1BL_HUMAN,Homo sapiens (Human), comp97561_c0_seq1,497,45.0704,0.47950126,9,44,,2.00E-43,Q6TV19,Endoribonuclease Dicer (EC 3.1.26.-),Endoribonuclease Dicer (EC 3.1.26.3),GO:0005524; GO:0008026; GO:0016442; GO:0005737; GO:0035279; GO:0046872; GO:0070883; GO:0031054; GO:0030422; GO:0004525; GO:0030423; GO:0021591,ATP binding; ATP-dependent helicase activity; RISC complex; cytoplasm; mRNA cleavage involved in gene silencing by miRNA; metal ion binding; pre-miRNA binding; pre-miRNA processing; production of siRNA involved in RNA interference; ribonuclease III activity; targeting of mRNA for destruction involved in RNA interference; ventricular system development,PF03368;PF00271;PF02170;PF04851;PF00636;,1.00E-42,CHOYP_DICER.1.3,,,,,,,DICER_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),apoptotic DNA fragmentation [GO:0006309]; gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of neurogenesis [GO:0050767]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; ventricular system development [GO:0021591] comp97570_c0_seq1,572,44.4056,0.69045112,5,33,,4.00E-15,Q5G267,Neurotrypsin (EC 3.4.21.-) (Serine protease 12),Neurotrypsin (EC 3.4.21.-) (Serine protease 12),GO:0030424; GO:0006887; GO:0005576; GO:0005886; GO:0006508; GO:0005044; GO:0004252,axon; exocytosis; extracellular region; plasma membrane; proteolysis; scavenger receptor activity; serine-type endopeptidase activity,PF00051;PF00530;PF00089;,,,,,,,,,NETR_MACMU,Macaca mulatta (Rhesus macaque),exocytosis [GO:0006887] comp97579_c0_seq1,339,47.4926,0.11078624,7,38,,5.00E-23,Q5VW36,Focadhesin,Focadhesin,GO:0005925; GO:0016021,focal adhesion; integral to membrane,PF11229;PF12530;,,,,,,,,,FOCAD_HUMAN,Homo sapiens (Human), comp97583_c1_seq1,256,37.8906,1.21228265,1,10,,1.00E-16,P02637,Sarcoplasmic calcium-binding protein (SCP),Sarcoplasmic calcium-binding protein (SCP),GO:0005509,calcium ion binding,,,,8.00E-21,ruditapes_c6244,,,,,SCP_MIZYE,Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis), comp97584_c0_seq1,438,41.5525,0.37562841,9,0,,2.00E-23,Q9HCF6,Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2),Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2),GO:0005262; GO:0005261; GO:0016021,calcium channel activity; cation channel activity; integral to membrane,PF00520;PF16519;,2.00E-28,CHOYP_TRPM3.3.7,,,,,,,TRPM3_HUMAN,Homo sapiens (Human),calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; detection of temperature stimulus [GO:0016048]; protein tetramerization [GO:0051262]; sensory perception of temperature stimulus [GO:0050951] comp97584_c1_seq1,221,46.1538,0.51389941,4,0,,,,,,,,,4.00E-13,CHOYP_TRPM2.1.12,,,,,,,,, comp97611_c0_seq1,605,45.4545,0.93231024,0,70,,1.00E-20,Q91574,ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) (XCART1),ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) (XCART1),GO:0007275; GO:0005634; GO:0043565; GO:0003700,multicellular organismal development; nucleus; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity,PF00046;PF03826;,2.00E-17,CHOYP_PHUM_PHUM165720.1.1,,,,,,,ALX1_XENLA,Xenopus laevis (African clawed frog),"neural crest cell migration [GO:0001755]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]" comp97680_c0_seq1,542,45.203,0.59564168,66,85,,1.00E-24,P26369,Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit),Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit),GO:0003723; GO:0008380; GO:0006397; GO:0048025; GO:0016607; GO:0000166; GO:0005681,"RNA binding; RNA splicing; mRNA processing; negative regulation of mRNA splicing, via spliceosome; nuclear speck; nucleotide binding; spliceosomal complex",PF00076;,2.00E-67,CHOYP_U2AF2.1.1,2.00E-46,ruditapes_c10844,,,,,U2AF2_MOUSE,Mus musculus (Mouse),"mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of RNA splicing [GO:0033120]; regulation of mitophagy [GO:1903146]; RNA splicing [GO:0008380]" comp97686_c0_seq1,223,43.4978,0.66838514,0,11,,6.00E-18,A7Y2X0,Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (xGlyT2) (Solute carrier family 6 member 5),Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (xGlyT2) (Solute carrier family 6 member 5),GO:0016021; GO:0005328,integral to membrane; neurotransmitter:sodium symporter activity,PF00209;,2.00E-11,CHOYP_SC6A5.1.7,,,,,,,SC6A5_XENLA,Xenopus laevis (African clawed frog), comp97715_c0_seq1,360,41.3889,0.56296731,8,31,,1.00E-22,P53809,Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2),Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2),GO:0005829; GO:0031210; GO:0008525,cytosol; phosphatidylcholine binding; phosphatidylcholine transporter activity,PF01852;,,,,,,,,,PPCT_RAT,Rattus norvegicus (Rat),phospholipid transport [GO:0015914] comp97718_c0_seq1,712,34.4101,0.90458245,18,75,,4.00E-06,Q9Y5X5,Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor),Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor),GO:0004930; GO:0015629; GO:0009582; GO:0005887; GO:0008188; GO:0007218; GO:0043408; GO:0045761; GO:2000479,G-protein coupled receptor activity; actin cytoskeleton; detection of abiotic stimulus; integral to plasma membrane; neuropeptide receptor activity; neuropeptide signaling pathway; regulation of MAPK cascade; regulation of adenylate cyclase activity; regulation of cAMP-dependent protein kinase activity,PF00001;,,,,,,,,,NPFF2_HUMAN,Homo sapiens (Human),cellular response to hormone stimulus [GO:0032870]; chemical synaptic transmission [GO:0007268]; detection of abiotic stimulus [GO:0009582]; G-protein coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408]; response to peptide [GO:1901652] comp97726_c0_seq2,584,40.7534,0.76078864,7,7,,3.00E-65,Q9ERE7,LDLR chaperone MESD (Mesoderm development candidate 2) (Mesoderm development protein),LDLR chaperone MESD (Mesoderm development candidate 2) (Mesoderm development protein),GO:0016055; GO:0005783; GO:0007498; GO:0005886; GO:0006457; GO:0034394,Wnt receptor signaling pathway; endoplasmic reticulum; mesoderm development; plasma membrane; protein folding; protein localization to cell surface,PF10185;,,,,,,,,,MESD_MOUSE,Mus musculus (Mouse),mesoderm development [GO:0007498]; protein folding [GO:0006457]; protein localization to cell surface [GO:0034394]; Wnt signaling pathway [GO:0016055] comp97728_c0_seq1,261,42.1456,1.04073027,0,30,,1.00E-07,O15403,Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6),Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6),GO:0005887; GO:0008028; GO:0015293,integral to plasma membrane; monocarboxylic acid transmembrane transporter activity; symporter activity,PF07690;,,,,,,,,,MOT7_HUMAN,Homo sapiens (Human),monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879] comp97753_c0_seq1,692,44.2197,1.18436479,25,28,,2.00E-09,Q9BXI9,Complement C1q tumor necrosis factor-related protein 6,Complement C1q tumor necrosis factor-related protein 6,GO:0005581; GO:0005615; GO:0070208,collagen; extracellular space; protein heterotrimerization,PF00386;PF01391;,,,,,,,,,C1QT6_HUMAN,Homo sapiens (Human),protein heterotrimerization [GO:0070208] comp97762_c1_seq1,396,44.697,0.79506515,15,0,,9.00E-23,P07032,"Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase isozyme CH2) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)","Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase isozyme CH2) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)",GO:0003998,acylphosphatase activity,PF00708;,,,,,,,,,ACYP1_CHICK,Gallus gallus (Chicken), comp97765_c0_seq1,565,41.0619,0.77375499,9,30,,2.00E-20,P18715,Gastrula zinc finger protein XlCGF26.1 (Fragment),Gastrula zinc finger protein XlCGF26.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG26_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp97775_c0_seq1,383,69.4517,1.24754341,0,0,,,,,,,,,4.00E-54,CHOYP_MTR_5G050970.1.1,,,,,,,,, comp97775_c0_seq2,426,67.3709,1.25885128,20,11,,,,,,,,,1.00E-143,CHOYP_LOC100353582.2.2,,,,,,,,, comp97797_c0_seq1,1068,42.9775,0.5886122,41,22,,1.00E-153,Q9H7M6,Zinc finger SWIM domain-containing protein 4,Zinc finger SWIM domain-containing protein 4,GO:0008270,zinc ion binding,,4.00E-155,CHOYP_ZSWM5.1.1,,,,,,,ZSWM4_HUMAN,Homo sapiens (Human), comp97804_c0_seq1,386,44.5596,0.11002206,10,6,,3.00E-24,Q3YK19,Fanconi anemia group J protein homolog (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1),Fanconi anemia group J protein homolog (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0046872; GO:0005654,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; metal ion binding; nucleoplasm",PF06733;PF13307;,2.00E-20,CHOYP_FANCJ.1.1,,,,,,,FANCJ_CHICK,Gallus gallus (Chicken),DNA repair [GO:0006281]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp97827_c0_seq1,447,41.8345,1.05387495,10,32,,2.00E-22,Q8R0Z5,Mitoferrin-2 (Mitochondrial RNA-splicing protein 3/4 homolog) (MRS3/4) (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28),Mitoferrin-2 (Mitochondrial RNA-splicing protein 3/4 homolog) (MRS3/4) (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28),GO:0016021; GO:0006811; GO:0055072; GO:0005743,integral to membrane; ion transport; iron ion homeostasis; mitochondrial inner membrane,PF00153;,3.00E-18,CHOYP_SLC25A37.1.1,,,,,,,MFRN2_MOUSE,Mus musculus (Mouse),iron ion homeostasis [GO:0055072]; small molecule metabolic process [GO:0044281]; translation [GO:0006412] comp9785_c0_seq1,461,44.0347,0.41455828,4,0,,3.00E-44,Q6IV78,Tafazzin,Tafazzin,GO:0016021; GO:0016746,"integral to membrane; transferase activity, transferring acyl groups",PF01553;,,,,,,,,,TAZ_SAISC,Saimiri sciureus (Common squirrel monkey),phospholipid metabolic process [GO:0006644] comp97873_c0_seq1,202,59.901,0.72145016,1,4,,1.00E-06,A9WNA0,Putative endo-alpha-N-acetylgalactosaminidase (EC 3.2.1.97),Putative endo-alpha-N-acetylgalactosaminidase (EC 3.2.1.97),GO:0005618; GO:0005576; GO:0033926; GO:0046872; GO:0050110,cell wall; extracellular region; glycopeptide alpha-N-acetylgalactosaminidase activity; metal ion binding; mucinaminylserine mucinaminidase activity,PF12905;PF08305;PF10633;,,,,,,,,,GH101_RENSM,Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235),metabolic process [GO:0008152] comp97876_c0_seq1,254,46.4567,0.44004133,3,15,,3.00E-19,Q4R633,Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1),Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1),GO:0005524; GO:0006915; GO:0005789; GO:0005739; GO:0005634; GO:0005886; GO:0004674; GO:0006950,ATP binding; apoptotic process; endoplasmic reticulum membrane; mitochondrion; nucleus; plasma membrane; protein serine/threonine kinase activity; response to stress,PF00069;PF00433;,1.00E-39,CHOYP_LOC100367908.2.2,,,,,,,SGK1_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey),apoptotic process [GO:0006915] comp97885_c1_seq1,606,48.6799,0.38636024,11,31,,1.00E-27,Q9ULJ6,Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17),Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17),GO:0048844; GO:0007569; GO:0005737; GO:0048589; GO:0003007; GO:0001701; GO:0016607; GO:0048146; GO:0045944; GO:0006351; GO:0001570; GO:0007296; GO:0008270,"artery morphogenesis; cell aging; cytoplasm; developmental growth; heart morphogenesis; in utero embryonic development; nuclear speck; positive regulation of fibroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; vasculogenesis; vitellogenesis; zinc ion binding",PF02891;,3.00E-26,CHOYP_BRAFLDRAFT_130685.1.1,,,,,,,ZMIZ1_HUMAN,Homo sapiens (Human),"artery morphogenesis [GO:0048844]; cell aging [GO:0007569]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296]" comp97887_c0_seq1,281,52.3132,0.31438525,12,5,,1.00E-09,Q502K3,Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C),,,PF00023;PF12796;,,,,,,,,,ANR52_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp9790_c0_seq1,451,41.2417,0.37847076,14,0,,5.00E-28,P0C928,Regulator of telomere elongation helicase 1 (EC 3.6.4.12),Regulator of telomere elongation helicase 1 (EC 3.6.4.12),GO:0051539; GO:0005524; GO:0004003; GO:0003677; GO:0006281; GO:0046872; GO:0005634,"4 iron, 4 sulfur cluster binding; ATP binding; ATP-dependent DNA helicase activity; DNA binding; DNA repair; metal ion binding; nucleus",PF06733;PF13307;,8.00E-26,CHOYP_RTEL1.1.1,,,,,,,RTEL1_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723] comp97912_c0_seq1,272,47.0588,0.27327697,4,9,,2.00E-18,O95163,Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150),Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150),GO:0016591; GO:0033588; GO:0005737; GO:0006955; GO:0005730; GO:0008607; GO:0030335; GO:0006461; GO:0006468; GO:0006357; GO:0004871; GO:0008023; GO:0006368,"DNA-directed RNA polymerase II, holoenzyme; Elongator holoenzyme complex; cytoplasm; immune response; nucleolus; phosphorylase kinase regulator activity; positive regulation of cell migration; protein complex assembly; protein phosphorylation; regulation of transcription from RNA polymerase II promoter; signal transducer activity; transcription elongation factor complex; transcription elongation from RNA polymerase II promoter",PF04762;,,,,,,,,,ELP1_HUMAN,Homo sapiens (Human),immune response [GO:0006955]; positive regulation of cell migration [GO:0030335]; protein complex assembly [GO:0006461]; protein phosphorylation [GO:0006468]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]; tRNA wobble uridine modification [GO:0002098] comp97913_c1_seq1,337,39.1691,0.46653275,9,16,,2.00E-43,Q8BID8,F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14),F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14),GO:0005737; GO:0042787; GO:0004842,cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12937;PF13516;,,,,,,,,,FXL14_MOUSE,Mus musculus (Mouse),protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787] comp97913_c2_seq1,325,39.6923,0.67670594,7,32,,5.00E-12,Q8BH16,F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2),F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2),GO:0016020; GO:0006513; GO:0006511; GO:0004842,membrane; protein monoubiquitination; ubiquitin-dependent protein catabolic process; ubiquitin-protein ligase activity,PF12937;PF13516;,3.00E-11,CHOYP_FXL14.1.1,,,,,,,FBXL2_MOUSE,Mus musculus (Mouse),protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] comp97919_c0_seq1,311,46.9453,0.89501786,2,35,,1.00E-21,Q54KF6,Protein DDB_G0287365,Protein DDB_G0287365,,,PF10162;,,,,,,,,,Y7365_DICDI,Dictyostelium discoideum (Slime mold), comp97921_c0_seq1,431,44.3155,0.38020007,16,21,,8.00E-31,Q9EQG6,Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein),GO:0030165; GO:0016482; GO:0005829; GO:0016021; GO:0005770; GO:0038180; GO:0010976; GO:0043234; GO:0019901; GO:0019887,PDZ domain binding; cytoplasmic transport; cytosol; integral to membrane; late endosome; nerve growth factor signaling pathway; positive regulation of neuron projection development; protein complex; protein kinase binding; protein kinase regulator activity,PF12796;PF07693;,8.00E-32,CHOYP_LOC100700010.1.1,,,,,,,KDIS_RAT,Rattus norvegicus (Rat),activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976] comp97992_c0_seq1,373,46.6488,0.20290394,10,0,,3.00E-12,Q09225,Nose resistant to fluoxetine protein 6 (Protein nrf-6),Nose resistant to fluoxetine protein 6 (Protein nrf-6),GO:0016021; GO:0008289; GO:0006869; GO:0007275; GO:0016747,"integral to membrane; lipid binding; lipid transport; multicellular organismal development; transferase activity, transferring acyl groups other than amino-acyl groups",PF01757;,,,,,,,,,NRF6_CAEEL,Caenorhabditis elegans,lipid transport [GO:0006869]; multicellular organism development [GO:0007275] comp97995_c1_seq1,328,43.9024,0.69933017,25,0,,3.00E-07,P10394,Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease],GO:0015074; GO:0003723; GO:0006278; GO:0003964; GO:0004190; GO:0004519; GO:0090305; GO:0006508,DNA integration; RNA binding; RNA-dependent DNA replication; RNA-directed DNA polymerase activity; aspartic-type endopeptidase activity; endonuclease activity; nucleic acid phosphodiester bond hydrolysis; proteolysis,PF00665;PF00077;PF00078;PF09337;,,,,,,,,,POL4_DROME,Drosophila melanogaster (Fruit fly),DNA integration [GO:0015074] comp98044_c0_seq1,430,50.6977,0.39698105,19,3,,5.00E-28,Q5TGY1,Transmembrane and coiled-coil domain-containing protein 4,Transmembrane and coiled-coil domain-containing protein 4,GO:0016021,integral to membrane,PF05277;,1.00E-23,CHOYP_TMCO4.1.1,,,,,,,TMCO4_HUMAN,Homo sapiens (Human), comp98051_c0_seq1,787,41.0419,0.39276193,22,35,,,,,,,,,2.00E-29,CHOYP_LR14B.1.1,,,,,,,,, comp98057_c1_seq1,248,43.1452,0.70991888,5,9,,1.00E-10,O15247,Chloride intracellular channel protein 2 (XAP121),Chloride intracellular channel protein 2 (XAP121),GO:0005254; GO:0034707; GO:0005737; GO:0004602; GO:0060315; GO:0005634; GO:0051099; GO:0010881; GO:0005247,chloride channel activity; chloride channel complex; cytoplasm; glutathione peroxidase activity; negative regulation of ryanodine-sensitive calcium-release channel activity; nucleus; positive regulation of binding; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; voltage-gated chloride channel activity,PF13409;,2.00E-18,CHOYP_LOAG_05718.1.1,,,,,,,CLIC2_HUMAN,Homo sapiens (Human),negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]; transport [GO:0006810] comp98057_c2_seq1,269,40.5204,1.18422689,2,4,,6.00E-06,Q9FWR4,"Glutathione S-transferase DHAR1, mitochondrial (EC 2.5.1.18) (Chloride intracellular channel homolog 1) (CLIC homolog 1) (Glutathione-dependent dehydroascorbate reductase 1) (AtDHAR1) (GSH-dependent dehydroascorbate reductase 1) (mtDHAR)","Glutathione S-transferase DHAR1, mitochondrial (EC 2.5.1.18) (Chloride intracellular channel homolog 1) (CLIC homolog 1) (Glutathione-dependent dehydroascorbate reductase 1) (AtDHAR1) (GSH-dependent dehydroascorbate reductase 1) (mtDHAR)",GO:0048046; GO:0009570; GO:0005507; GO:0005829; GO:0006952; GO:0045174; GO:0004364; GO:0005739; GO:0005777; GO:0005886; GO:0010731; GO:0043903; GO:0009753; GO:0010193; GO:0009610; GO:0009636; GO:0010043; GO:0005773; GO:0005244,"apoplast; chloroplast stroma; copper ion binding; cytosol; defense response; glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; mitochondrion; peroxisome; plasma membrane; protein glutathionylation; regulation of symbiosis, encompassing mutualism through parasitism; response to jasmonic acid stimulus; response to ozone; response to symbiotic fungus; response to toxic substance; response to zinc ion; vacuole; voltage-gated ion channel activity",PF13417;,,,,,,,,,DHAR1_ARATH,Arabidopsis thaliana (Mouse-ear cress),"defense response [GO:0006952]; protein glutathionylation [GO:0010731]; regulation of symbiosis, encompassing mutualism through parasitism [GO:0043903]; response to jasmonic acid [GO:0009753]; response to ozone [GO:0010193]; response to symbiotic fungus [GO:0009610]; response to zinc ion [GO:0010043]" comp98065_c0_seq1,650,45.5385,0.54706012,17,26,,5.00E-33,Q12553,Xanthine dehydrogenase (EC 1.17.1.4) (Purine hydroxylase I),Xanthine dehydrogenase (EC 1.17.1.4) (Purine hydroxylase I),GO:0051537; GO:0008762; GO:0009055; GO:0050660; GO:0005506; GO:0043546; GO:0005777; GO:0009115; GO:0004854; GO:0004855,"2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; molybdopterin cofactor binding; peroxisome; xanthine catabolic process; xanthine dehydrogenase activity; xanthine oxidase activity",PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;,,,,,,,,,XDH_EMENI,Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans),purine nucleobase catabolic process [GO:0006145]; xanthine catabolic process [GO:0009115] comp98082_c0_seq1,285,41.0526,0.93078069,0,25,,2.00E-06,O62761,Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase),Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase),GO:0003990; GO:0004091; GO:0005576; GO:0016020,acetylcholinesterase activity; carboxylesterase activity; extracellular region; membrane,PF08674;PF00135;,7.00E-37,CHOYP_LOC100644613.1.1,,,,,,,CHLE_PANTT,Panthera tigris tigris (Bengal tiger), comp98088_c0_seq1,267,43.0712,0.89172455,2,19,,4.00E-17,Q5T4D3,Transmembrane and TPR repeat-containing protein 4,Transmembrane and TPR repeat-containing protein 4,GO:0016021,integral to membrane,PF08409;PF13181;,,,,,,,,,TMTC4_HUMAN,Homo sapiens (Human), comp98090_c0_seq1,351,62.963,0.98067004,0,22,,1.00E-10,Q82B58,Putative ABC transporter ATP-binding protein SAV_5847 (EC 3.6.3.-),Putative ABC transporter ATP-binding protein SAV_5847 (EC 3.6.3.-),GO:0005524; GO:0006200; GO:0016887; GO:0005886; GO:0006810,ATP binding; ATP catabolic process; ATPase activity; plasma membrane; transport,PF00005;,,,,,,,,,Y5847_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),transport [GO:0006810] comp98137_c0_seq1,485,45.9794,0.51693887,13,37,,2.00E-23,P31396,Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4),GO:0000977; GO:0004879; GO:0007552; GO:0016319; GO:0000122; GO:0005634; GO:0045944; GO:0040034; GO:0003707; GO:0004887; GO:0008270,"RNA polymerase II regulatory region sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metamorphosis; mushroom body development; negative regulation of transcription from RNA polymerase II promoter; nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of development, heterochronic; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding",PF00104;PF00105;,,,,,,,,,HR3_DROME,Drosophila melanogaster (Fruit fly),"metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]" comp98152_c0_seq1,548,48.3577,0.38191432,19,30,,1.00E-41,Q9D3S3,Sorting nexin-29,Sorting nexin-29,GO:0007154; GO:0035091,cell communication; phosphatidylinositol binding,PF00787;PF02759;,3.00E-64,CHOYP_SNX29.1.1,,,,,,,SNX29_MOUSE,Mus musculus (Mouse), comp9815_c0_seq1,209,43.5407,0.91571864,4,21,,,,,,,,,,,6.00E-21,ruditapes_c10755,,,,,,, comp98169_c0_seq1,895,41.2291,1.01672368,73,0,,,,,,,,,,,4.00E-18,ruditapes_c19003,,,,,,, comp98178_c1_seq1,721,46.8793,0.55896226,15,3,,1.00E-118,P39057,"Dynein beta chain, ciliary","Dynein beta chain, ciliary",GO:0005524; GO:0006200; GO:0016887; GO:0030030; GO:0005929; GO:0005737; GO:0030286; GO:0005874; GO:0003777; GO:0007018,ATP binding; ATP catabolic process; ATPase activity; cell projection organization; cilium; cytoplasm; dynein complex; microtubule; microtubule motor activity; microtubule-based movement,PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;,5.00E-164,CHOYP_DYHC.1.3,,,,,,,DYHC_ANTCR,Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina),cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] comp98182_c0_seq1,245,43.6735,0.34624081,4,3,,7.00E-36,P38530,Heat shock factor protein 2 (HSF 2) (HSF 3B) (HSTF 3B) (Heat shock transcription factor 2) (HSTF 2),Heat shock factor protein 2 (HSF 2) (HSF 3B) (HSTF 3B) (Heat shock transcription factor 2) (HSTF 2),GO:0001162; GO:0005737; GO:0005634; GO:0045944; GO:0006950; GO:0003700; GO:0007283; GO:0006351,"RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding; cytoplasm; nucleus; positive regulation of transcription from RNA polymerase II promoter; response to stress; sequence-specific DNA binding transcription factor activity; spermatogenesis; transcription, DNA-dependent",PF00447;PF06546;,4.00E-27,CHOYP_HSF1.2.2,,,,,,,HSF2_CHICK,Gallus gallus (Chicken),negative regulation of protein ubiquitination [GO:0031397]; protein homotrimerization [GO:0070207]; protein stabilization [GO:0050821]; response to light stimulus [GO:0009416]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to sodium arsenite [GO:1903935]; spermatogenesis [GO:0007283] comp98182_c1_seq1,727,44.4292,0.47450439,22,20,,8.00E-34,P38529,Heat shock factor protein 1 (HSF 1) (HSF 3A) (HSTF 3A) (Heat shock transcription factor 1) (HSTF 1),Heat shock factor protein 1 (HSF 1) (HSF 3A) (HSTF 3A) (Heat shock transcription factor 1) (HSTF 1),GO:0005737; GO:0005634; GO:0009408; GO:0043565; GO:0003700; GO:0006351,"cytoplasm; nucleus; response to heat; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00447;PF06546;,,,,,,,,,HSF1_CHICK,Gallus gallus (Chicken),"cellular response to heat [GO:0034605]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; transcription, DNA-templated [GO:0006351]" comp98188_c0_seq1,336,40.1786,0.75459692,4,20,,8.00E-27,Q0IID7,Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48),Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48),GO:0005794; GO:0017017; GO:0005737; GO:0046329; GO:0043508; GO:0005634; GO:0035335; GO:0004725,Golgi apparatus; MAP kinase tyrosine/serine/threonine phosphatase activity; cytoplasm; negative regulation of JNK cascade; negative regulation of JUN kinase activity; nucleus; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00782;PF00581;,2.00E-19,CHOYP_PHUM_PHUM490910.1.1,,,,,,,DUS10_BOVIN,Bos taurus (Bovine),inactivation of MAPK activity [GO:0000188]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496] comp98190_c0_seq1,522,43.4866,0.69019039,6,46,,2.00E-14,B3A0Q8,Peroxidase-like protein 3 (Fragment),Peroxidase-like protein 3 (Fragment),GO:0005576; GO:0020037; GO:0004601; GO:0006979,extracellular region; heme binding; peroxidase activity; response to oxidative stress,PF03098;,,,,,,,,,PLSP2_LOTGI,Lottia gigantea (Giant owl limpet),response to oxidative stress [GO:0006979] comp98190_c1_seq1,324,42.9012,0.74017268,0,79,,5.00E-10,P22079,Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO),Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO),GO:0005737; GO:0005615; GO:0020037; GO:0042744; GO:0046872; GO:0004601; GO:0006979,cytoplasm; extracellular space; heme binding; hydrogen peroxide catabolic process; metal ion binding; peroxidase activity; response to oxidative stress,PF03098;,,,,,,,,,PERL_HUMAN,Homo sapiens (Human),defense response to bacterium [GO:0042742]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] comp98191_c0_seq1,224,64.2857,1.30841918,1,0,,2.00E-19,O25225,GTP-binding protein TypA/BipA homolog,GTP-binding protein TypA/BipA homolog,GO:0005525; GO:0006184; GO:0003924,GTP binding; GTP catabolic process; GTPase activity,PF00679;PF03144;,,,,,,,,,TYPA_HELPY,Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori), comp98220_c0_seq1,339,60.472,1.2186486,0,33,,5.00E-28,Q6AA93,Exodeoxyribonuclease 7 small subunit (EC 3.1.11.6) (Exodeoxyribonuclease VII small subunit) (Exonuclease VII small subunit),Exodeoxyribonuclease 7 small subunit (EC 3.1.11.6) (Exodeoxyribonuclease VII small subunit) (Exonuclease VII small subunit),GO:0006308; GO:0005737; GO:0008855; GO:0009318; GO:0090305,DNA catabolic process; cytoplasm; exodeoxyribonuclease VII activity; exodeoxyribonuclease VII complex; nucleic acid phosphodiester bond hydrolysis,PF02609;,,,,,,,,,EX7S_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),DNA catabolic process [GO:0006308] comp98237_c1_seq1,576,42.8819,1.02345598,22,3,,2.00E-10,P04462,"Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal) (Fragment)","Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal) (Fragment)",GO:0005524; GO:0003774; GO:0030016; GO:0032982,ATP binding; motor activity; myofibril; myosin filament,PF01576;,5.00E-30,CHOYP_MYS.4.7,6.00E-33,ruditapes2_c3813,,,,,MYH8_RAT,Rattus norvegicus (Rat), comp98242_c0_seq1,223,41.704,1.35950446,4,0,,3.00E-09,Q80ZA4,Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86),GO:0016021,integral to membrane,PF10162;PF07691;PF01833;,,,,,,,,,PKHL1_MOUSE,Mus musculus (Mouse), comp98246_c0_seq1,751,47.6698,0.44661244,14,13,,4.00E-29,Q14005,Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)],Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)],GO:0005737; GO:0005615; GO:0006955; GO:0050930; GO:0030595; GO:0019048; GO:0005634; GO:0005886; GO:0006355; GO:0006351,"cytoplasm; extracellular space; immune response; induction of positive chemotaxis; leukocyte chemotaxis; modulation by virus of host morphology or physiology; nucleus; plasma membrane; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00595;,,,,,,,,,IL16_HUMAN,Homo sapiens (Human),"immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; leukocyte chemotaxis [GO:0030595]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]" comp98246_c1_seq1,802,45.1372,0.64295493,29,36,,7.00E-26,O15018,PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2],PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2],GO:0007155; GO:0005911; GO:0005783; GO:0005576; GO:0005634,cell adhesion; cell-cell junction; endoplasmic reticulum; extracellular region; nucleus,PF00595;,1.00E-38,CHOYP_BRAFLDRAFT_125231.1.1,,,,,,,PDZD2_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155] comp98248_c0_seq1,744,38.172,0.96753422,0,140,,2.00E-11,P35346,Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R),Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R),GO:0007187; GO:0042593; GO:0005887; GO:0008285; GO:0050796; GO:0004994,"G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; glucose homeostasis; integral to plasma membrane; negative regulation of cell proliferation; regulation of insulin secretion; somatostatin receptor activity",PF00001;,,,,,,,,,SSR5_HUMAN,Homo sapiens (Human),"adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to glucocorticoid stimulus [GO:0071385]; chemical synaptic transmission [GO:0007268]; glucose homeostasis [GO:0042593]; G-protein coupled receptor signaling pathway [GO:0007186]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of cell proliferation [GO:0008285]; positive regulation of cytokinesis [GO:0032467]; regulation of insulin secretion [GO:0050796]" comp98255_c0_seq1,558,41.2186,0.8046238,7,46,,5.00E-23,Q8BJL1,F-box only protein 30,F-box only protein 30 (Muscle ubiquitin ligase of SCF complex in atrophy-1) (MUSA1),GO:0004842; GO:0008270,ubiquitin-protein ligase activity; zinc ion binding,PF15966;PF15965;,,,,,,,,,FBX30_MOUSE,Mus musculus (Mouse), comp98259_c0_seq1,228,45.614,0.85833735,7,0,,7.00E-27,Q7ZV79,Uridine-cytidine kinase 2-B (UCK 2-B) (EC 2.7.1.48) (Cytidine monophosphokinase 2-B) (Uridine monophosphokinase 2-B),Uridine-cytidine kinase 2-B (UCK 2-B) (EC 2.7.1.48) (Cytidine monophosphokinase 2-B) (Uridine monophosphokinase 2-B),GO:0005524; GO:0044211; GO:0044206; GO:0016773; GO:0004849,"ATP binding; CTP salvage; UMP salvage; phosphotransferase activity, alcohol group as acceptor; uridine kinase activity",PF00485;,,,,,,,,,UCK2B_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),CMP salvage [GO:0006238]; CTP salvage [GO:0044211]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206] comp98259_c1_seq1,203,43.3498,0.94837012,5,12,,3.00E-23,Q9VC99,Probable uridine-cytidine kinase (UCK) (EC 2.7.1.48) (Cytidine monophosphokinase) (Uridine monophosphokinase),Probable uridine-cytidine kinase (UCK) (EC 2.7.1.48) (Cytidine monophosphokinase) (Uridine monophosphokinase),GO:0005524; GO:0044211; GO:0044206; GO:0006909; GO:0016773; GO:0004849,"ATP binding; CTP salvage; UMP salvage; phagocytosis; phosphotransferase activity, alcohol group as acceptor; uridine kinase activity",PF00485;,6.00E-11,CHOYP_UCK2.1.1,,,,,,,UCK_DROME,Drosophila melanogaster (Fruit fly),CMP salvage [GO:0006238]; CTP salvage [GO:0044211]; phagocytosis [GO:0006909]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206] comp98260_c0_seq1,385,43.3766,0.27706187,13,16,,4.00E-28,Q812E8,Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase),Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase),GO:0005524; GO:0009435; GO:0003952; GO:0016810,"ATP binding; NAD biosynthetic process; NAD+ synthase (glutamine-hydrolyzing) activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",PF00795;PF02540;,8.00E-38,CHOYP_NEMVEDRAFT_V1G173435.1.1,,,,,,,NADE_RAT,Rattus norvegicus (Rat),NAD biosynthetic process [GO:0009435] comp98261_c0_seq1,286,45.1049,0.75999966,5,0,,3.00E-28,Q9EQY0,Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0006987; GO:0007050; GO:0005789; GO:0004521; GO:0030176; GO:0070059; GO:0006397; GO:0000287; GO:0005739; GO:0005637; GO:1900103; GO:0046777; GO:0004674; GO:0006355; GO:0006351,"ATP binding; activation of signaling protein activity involved in unfolded protein response; cell cycle arrest; endoplasmic reticulum membrane; endoribonuclease activity; integral to endoplasmic reticulum membrane; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; mRNA processing; magnesium ion binding; mitochondrion; nuclear inner membrane; positive regulation of endoplasmic reticulum unfolded protein response; protein autophosphorylation; protein serine/threonine kinase activity; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00069;PF06479;,4.00E-33,CHOYP_BRAFLDRAFT_118819.1.2,,,,,,,ERN1_MOUSE,Mus musculus (Mouse),"activation of JUN kinase activity [GO:0007257]; activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cell cycle arrest [GO:0007050]; cellular response to glucose stimulus [GO:0071333]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endoplasmic reticulum unfolded protein response [GO:0030968]; endothelial cell proliferation [GO:0001935]; insulin metabolic process [GO:1901142]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA cleavage [GO:0006379]; mRNA endonucleolytic cleavage involved in unfolded protein response [GO:0070055]; mRNA splicing, via endonucleolytic cleavage and ligation [GO:0070054]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine trans-autophosphorylation [GO:1990579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]" comp98261_c1_seq1,221,46.6063,0.42174116,3,14,,7.00E-16,P32361,Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)],GO:0005524; GO:0005789; GO:0030968; GO:0004521; GO:0031505; GO:0006020; GO:0016021; GO:0006397; GO:0046872; GO:0005634; GO:0042803; GO:0051260; GO:0004674; GO:0036290; GO:0006355; GO:0006351; GO:0051082,"ATP binding; endoplasmic reticulum membrane; endoplasmic reticulum unfolded protein response; endoribonuclease activity; fungal-type cell wall organization; inositol metabolic process; integral to membrane; mRNA processing; metal ion binding; nucleus; protein homodimerization activity; protein homooligomerization; protein serine/threonine kinase activity; protein trans-autophosphorylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; unfolded protein binding",PF00069;PF06479;,,,,,,,,,IRE1_YEAST,Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast),"endoplasmic reticulum unfolded protein response [GO:0030968]; fungal-type cell wall organization [GO:0031505]; inositol metabolic process [GO:0006020]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein targeting to Golgi [GO:0000042]; protein trans-autophosphorylation [GO:0036290]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]" comp98263_c0_seq1,457,43.7637,0.32060154,6,0,,7.00E-08,Q9Y2I7,1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase),GO:0000285; GO:0016308; GO:0005524; GO:0000139; GO:0044267; GO:0031410; GO:0005829; GO:0031901; GO:0035556; GO:0031902; GO:0045121; GO:0046872; GO:0032288; GO:0048471; GO:0043813; GO:0034504; GO:0042147; GO:0044281,"1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; Golgi membrane; cellular protein metabolic process; cytoplasmic vesicle; cytosol; early endosome membrane; intracellular signal transduction; late endosome membrane; membrane raft; metal ion binding; myelin assembly; perinuclear region of cytoplasm; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; protein localization to nucleus; retrograde transport, endosome to Golgi; small molecule metabolic process",PF00118;PF00610;PF01363;PF01504;,,,,,,,,,FYV1_HUMAN,Homo sapiens (Human),"intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]" comp98266_c0_seq1,298,49.3289,0.27965148,7,4,,2.00E-20,Q3UHQ6,Protein dopey-2,Protein dopey-2,GO:0015031,protein transport,PF04118;,3.00E-35,CHOYP_PHUM_PHUM092120.1.1,,,,,,,DOP2_MOUSE,Mus musculus (Mouse),cognition [GO:0050890]; protein transport [GO:0015031] comp98287_c0_seq1,434,65.6682,1.03111659,0,29,,3.00E-56,Q82I33,Histidine ammonia-lyase (Histidase) (EC 4.3.1.3),Histidine ammonia-lyase (Histidase) (EC 4.3.1.3),GO:0009058; GO:0005737; GO:0004397; GO:0019556; GO:0019557,biosynthetic process; cytoplasm; histidine ammonia-lyase activity; histidine catabolic process to glutamate and formamide; histidine catabolic process to glutamate and formate,PF00221;,,,,,,,,,HUTH_STRAW,Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680),histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] comp98290_c3_seq1,241,42.7386,0.65255361,7,5,,5.00E-08,Q7RTR2,Protein NLRC3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (Nucleotide-binding oligomerization domain protein 3),Protein NLRC3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (Nucleotide-binding oligomerization domain protein 3),GO:0005524; GO:0007249; GO:0042110; GO:0005737; GO:0043124; GO:0032088,ATP binding; I-kappaB kinase/NF-kappaB cascade; T cell activation; cytoplasm; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB transcription factor activity,PF13516;,,,,,,,,,NLRC3_HUMAN,Homo sapiens (Human),I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] comp98312_c0_seq1,371,42.5876,0.50296123,2,41,,3.00E-20,Q4R684,Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2),Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2),GO:0008237; GO:0006508; GO:0008270,metallopeptidase activity; proteolysis; zinc ion binding,PF07998;,3.00E-36,CHOYP_LOC100632148.1.1,,,,,,,AMZ2_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp98322_c0_seq1,398,44.9749,0.49813049,12,2,,2.00E-43,Q8K4Q7,Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase),Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase),GO:0005524; GO:0003951; GO:0001729; GO:0006672; GO:0004143; GO:0016021; GO:0000287; GO:0005739; GO:0005634; GO:0007205,ATP binding; NAD+ kinase activity; ceramide kinase activity; ceramide metabolic process; diacylglycerol kinase activity; integral to membrane; magnesium ion binding; mitochondrion; nucleus; protein kinase C-activating G-protein coupled receptor signaling pathway,PF00781;,,,,,,,,,CERK1_MOUSE,Mus musculus (Mouse),ceramide metabolic process [GO:0006672] comp98346_c0_seq1,350,42.2857,0.72412444,4,37,,4.00E-17,P27169,Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1),Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1),GO:0019439; GO:0004063; GO:0004064; GO:0005509; GO:0046395; GO:0008203; GO:0043231; GO:0046434; GO:0046470; GO:0005543; GO:0051099; GO:0010875; GO:0032411; GO:0042803; GO:0009605; GO:0009636; GO:0034366,aromatic compound catabolic process; aryldialkylphosphatase activity; arylesterase activity; calcium ion binding; carboxylic acid catabolic process; cholesterol metabolic process; intracellular membrane-bounded organelle; organophosphate catabolic process; phosphatidylcholine metabolic process; phospholipid binding; positive regulation of binding; positive regulation of cholesterol efflux; positive regulation of transporter activity; protein homodimerization activity; response to external stimulus; response to toxic substance; spherical high-density lipoprotein particle,PF01731;,,,,,,,,,PON1_HUMAN,Homo sapiens (Human),aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; cholesterol metabolic process [GO:0008203]; organophosphate catabolic process [GO:0046434]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of binding [GO:0051099]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transporter activity [GO:0032411]; response to external stimulus [GO:0009605]; response to fatty acid [GO:0070542]; response to fluoride [GO:1902617]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636] comp98361_c0_seq1,856,46.3785,0.54383768,24,39,,5.00E-54,Q96PX9,Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B),Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B),GO:0005089; GO:0005543; GO:0035023,Rho guanyl-nucleotide exchange factor activity; phospholipid binding; regulation of Rho protein signal transduction,PF00621;,3.00E-54,CHOYP_LOC100377600.1.2,,,,,,,PKH4B_HUMAN,Homo sapiens (Human),regulation of Rho protein signal transduction [GO:0035023] comp98365_c0_seq1,378,39.418,0.55531524,12,19,,2.00E-45,Q16560,U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog),U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog),GO:0003723; GO:0008380; GO:0005689; GO:0006397; GO:0000166,RNA binding; RNA splicing; U12-type spliceosomal complex; mRNA processing; nucleotide binding,PF00076;,,,,,,,,,U1SBP_HUMAN,Homo sapiens (Human),"mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]" comp98373_c0_seq1,203,49.7537,0.24019421,0,15,,2.00E-23,Q5RFU0,Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase),Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase),GO:0004091; GO:0005764; GO:0001681,carboxylesterase activity; lysosome; sialate O-acetylesterase activity,PF03629;,2.00E-16,CHOYP_BRAFLDRAFT_217332.2.2,1.00E-11,ruditapes_c28352,,,,,SIAE_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp98375_c1_seq1,410,46.3415,0.45585897,26,17,,4.00E-25,Q64417,Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14),Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14),GO:0070330; GO:0005789; GO:0020037; GO:0005506,aromatase activity; endoplasmic reticulum membrane; heme binding; iron ion binding,PF00067;,3.00E-12,CHOYP_BRAFLDRAFT_61250.6.14,,,,,,,CP3AE_CAVPO,Cavia porcellus (Guinea pig), comp98375_c2_seq1,713,42.216,0.79192702,25,28,,2.00E-59,P51871,Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6),GO:0070330; GO:0005789; GO:0020037; GO:0006954; GO:0005506; GO:0006691,aromatase activity; endoplasmic reticulum membrane; heme binding; inflammatory response; iron ion binding; leukotriene metabolic process,PF00067;,2.00E-22,CHOYP_BRAFLDRAFT_61250.8.14,,,,,,,CP4F6_RAT,Rattus norvegicus (Rat),inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691] comp98418_c0_seq1,1219,45.5291,0.52659151,61,46,,8.00E-27,Q5JR59,Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa),Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa),GO:0005737; GO:0005874; GO:0008017,cytoplasm; microtubule; microtubule binding,,1.00E-60,CHOYP_LOC763960.1.2,,,,,,,MTUS2_HUMAN,Homo sapiens (Human), comp98421_c0_seq1,335,49.8507,0.88421841,3,35,,6.00E-14,Q3UTY6,Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4),Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4),GO:0048251; GO:0004222; GO:0001527,elastic fiber assembly; metalloendopeptidase activity; microfibril,PF05986;PF08686;PF00090;,,,,,,,,,THSD4_MOUSE,Mus musculus (Mouse),elastic fiber assembly [GO:0048251] comp98432_c1_seq1,477,45.7023,0.73633186,10,30,,3.00E-57,Q9QYK7,RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669),RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669),GO:0005769; GO:0005634; GO:0042787; GO:0055037; GO:0000151; GO:0006511; GO:0008270,early endosome; nucleus; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; recycling endosome; ubiquitin ligase complex; ubiquitin-dependent protein catabolic process; zinc ion binding,PF13639;,3.00E-44,CHOYP_RNF11.2.2,,,,,,,RNF11_MOUSE,Mus musculus (Mouse),protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511] comp98458_c0_seq1,427,47.3068,0.4425169,14,31,,6.00E-11,Q58820,L-sulfolactate dehydrogenase (EC 1.1.1.337) ((R)-2-hydroxyacid dehydrogenase) ((R)-sulfolactate dehydrogenase) (L-2-hydroxycarboxylate dehydrogenase (NAD(+))),L-sulfolactate dehydrogenase (EC 1.1.1.337) ((R)-2-hydroxyacid dehydrogenase) ((R)-sulfolactate dehydrogenase) (L-2-hydroxycarboxylate dehydrogenase (NAD(+))),GO:0019295; GO:0005737; GO:0016491; GO:0050545,coenzyme M biosynthetic process; cytoplasm; oxidoreductase activity; sulfopyruvate decarboxylase activity,PF02615;,5.00E-41,CHOYP_LOC101069440.1.3,,,,,,,COMC_METJA,Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii),coenzyme M biosynthetic process [GO:0019295] comp98467_c0_seq1,493,42.5963,0.31713263,9,51,,1.00E-17,Q6AYF6,Glycosyltransferase 8 domain-containing protein 1 (EC 2.4.1.-),Glycosyltransferase 8 domain-containing protein 1 (EC 2.4.1.-),GO:0016021; GO:0016757,"integral to membrane; transferase activity, transferring glycosyl groups",PF01501;,,,,,,,,,GL8D1_RAT,Rattus norvegicus (Rat),polysaccharide biosynthetic process [GO:0000271] comp98476_c0_seq1,309,41.7476,0.9033606,0,6,,3.00E-06,Q8K482,EMILIN-2 (Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2),EMILIN-2 (Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2),GO:0007155; GO:0005581,cell adhesion; collagen,PF00386;PF07546;,,,,,,,,,EMIL2_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp98478_c0_seq1,494,40.8907,0.20122034,5,0,,8.00E-08,A2AVA0,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)","Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)",GO:0005509; GO:0007155; GO:0003682; GO:0005737; GO:0005576; GO:0016020,calcium ion binding; cell adhesion; chromatin binding; cytoplasm; extracellular region; membrane,PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;,,,,,,,,,SVEP1_MOUSE,Mus musculus (Mouse),cell adhesion [GO:0007155] comp98496_c0_seq1,465,51.3978,0.68539328,0,0,,5.00E-34,Q9Y6N7,Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1),Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1),GO:0035385; GO:0006919; GO:0030673; GO:0008046; GO:0016199; GO:0002042; GO:0009986; GO:0021836; GO:0005737; GO:0007156; GO:0042802; GO:0005887; GO:0060763; GO:0070100; GO:0033600; GO:0050925; GO:0050772,Roundabout signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; axolemma; axon guidance receptor activity; axon midline choice point recognition; cell migration involved in sprouting angiogenesis; cell surface; chemorepulsion involved in postnatal olfactory bulb interneuron migration; cytoplasm; homophilic cell adhesion; identical protein binding; integral to plasma membrane; mammary duct terminal end bud growth; negative regulation of chemokine-mediated signaling pathway; negative regulation of mammary gland epithelial cell proliferation; negative regulation of negative chemotaxis; positive regulation of axonogenesis,PF00041;PF07679;,,,,,,,,,ROBO1_HUMAN,Homo sapiens (Human),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Rho protein signal transduction [GO:0035025]; Roundabout signaling pathway [GO:0035385] comp98496_c0_seq2,961,50.1561,0.58414359,24,33,,2.00E-72,O89026,Roundabout homolog 1,Roundabout homolog 1,GO:0030673; GO:0016199; GO:0016021; GO:0060763; GO:0008285; GO:0021891,axolemma; axon midline choice point recognition; integral to membrane; mammary duct terminal end bud growth; negative regulation of cell proliferation; olfactory bulb interneuron development,PF00041;PF07679;,,,,,,,,,ROBO1_MOUSE,Mus musculus (Mouse),activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Rho protein signal transduction [GO:0035025]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281] comp98499_c0_seq1,538,45.9108,0.57333,5,6,,2.00E-09,Q196X6,Putative ubiquitin thioesterase 232R (EC 3.4.19.12),Putative ubiquitin thioesterase 232R (EC 3.4.19.12),GO:0006353; GO:0008234; GO:0006508,"DNA-dependent transcription, termination; cysteine-type peptidase activity; proteolysis",PF02338;PF07498;,,,,,,,,,VF232_IIV3,Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus),"DNA-templated transcription, termination [GO:0006353]" comp98500_c0_seq1,373,41.555,0.62857595,10,11,,2.00E-16,Q4FZX7,Signal recognition particle receptor subunit beta (SR-beta),Signal recognition particle receptor subunit beta (SR-beta),GO:0005525; GO:0016324; GO:0009925; GO:0005905; GO:0005881; GO:0005769; GO:0030139; GO:0005789; GO:0016021; GO:0005770; GO:0005739; GO:0048471; GO:0055037; GO:0007264,GTP binding; apical plasma membrane; basal plasma membrane; coated pit; cytoplasmic microtubule; early endosome; endocytic vesicle; endoplasmic reticulum membrane; integral to membrane; late endosome; mitochondrion; perinuclear region of cytoplasm; recycling endosome; small GTPase mediated signal transduction,PF09439;,,,,,,,,,SRPRB_RAT,Rattus norvegicus (Rat),small GTPase mediated signal transduction [GO:0007264] comp98506_c0_seq1,423,51.773,0.57210642,11,2,,2.00E-12,Q9LJN4,Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-),GO:0005975; GO:0005618; GO:0004553; GO:0005578,"carbohydrate metabolic process; cell wall; hydrolase activity, hydrolyzing O-glycosyl compounds; proteinaceous extracellular matrix",PF14310;PF00933;PF01915;,1.00E-29,CHOYP_LOC100375395.1.2,,,,,,,BXL5_ARATH,Arabidopsis thaliana (Mouse-ear cress),carbohydrate metabolic process [GO:0005975] comp98528_c0_seq1,312,66.3462,1.22861075,3,19,,8.00E-46,Q6AAD3,Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)],GO:0006048; GO:0003977; GO:0000902; GO:0005737; GO:0019134; GO:0009245; GO:0009103; GO:0000287; GO:0009252; GO:0008360,UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine diphosphorylase activity; cell morphogenesis; cytoplasm; glucosamine-1-phosphate N-acetyltransferase activity; lipid A biosynthetic process; lipopolysaccharide biosynthetic process; magnesium ion binding; peptidoglycan biosynthetic process; regulation of cell shape,PF00132;PF12804;,,,,,,,,,GLMU_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] comp98532_c0_seq1,836,42.3445,1.12266631,50,32,,2.00E-09,Q09715,Transcriptional repressor tup11,Transcriptional repressor tup11,GO:0006342; GO:0005829; GO:0042393; GO:0045014; GO:0000122; GO:0000790; GO:0043234; GO:0003714; GO:0006351,"chromatin silencing; cytosol; histone binding; negative regulation of transcription by glucose; negative regulation of transcription from RNA polymerase II promoter; nuclear chromatin; protein complex; transcription corepressor activity; transcription, DNA-dependent",PF08581;PF00400;,,,,,,,,,TUP11_SCHPO,Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast),"chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]" comp98547_c0_seq1,314,56.051,1.24343366,0,4,,3.00E-10,P0A9A1,Ferritin-1 (EC 1.16.3.1),Bacterial non-heme ferritin (EC 1.16.3.2) (Ferritin-1),GO:0006879; GO:0005737; GO:0008199; GO:0004322; GO:0006826,cellular iron ion homeostasis; cytoplasm; ferric iron binding; ferroxidase activity; iron ion transport,PF00210;,,,,,,,,,FTNA_SHIFL,Shigella flexneri,cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] comp98563_c0_seq1,331,40.1813,0.52555884,7,31,,2.00E-24,Q7ZYQ3,Choline/ethanolaminephosphotransferase 1 (EC 2.7.8.1) (EC 2.7.8.2),Choline/ethanolaminephosphotransferase 1 (EC 2.7.8.1) (EC 2.7.8.2),GO:0006657; GO:0004142; GO:0005789; GO:0004307; GO:0016021; GO:0046872; GO:0031965; GO:0006646,CDP-choline pathway; diacylglycerol cholinephosphotransferase activity; endoplasmic reticulum membrane; ethanolaminephosphotransferase activity; integral to membrane; metal ion binding; nuclear membrane; phosphatidylethanolamine biosynthetic process,PF01066;,,,,,,,,,CEPT1_XENLA,Xenopus laevis (African clawed frog),phosphatidylethanolamine biosynthetic process [GO:0006646] comp98573_c0_seq1,556,48.2014,0.2795726,9,4,,1.00E-71,Q9D565,WD repeat-containing protein 64,WD repeat-containing protein 64,,,PF00400;,1.00E-93,CHOYP_LOC582771.1.1,,,,,,,WDR64_MOUSE,Mus musculus (Mouse), comp98573_c0_seq2,432,50.2315,0.29440919,0,0,,1.00E-06,Q9NDC9,Lissencephaly-1 homolog (Pronuclear migration abnormal protein 1),Lissencephaly-1 homolog (Pronuclear migration abnormal protein 1),GO:0005818; GO:0005938; GO:0030154; GO:0051301; GO:0051026; GO:0000777; GO:0009792; GO:0043652; GO:0000132; GO:0000776; GO:0040011; GO:0005874; GO:0005875; GO:0005815; GO:0007018; GO:0007100; GO:0007399; GO:0048477; GO:0048471; GO:0035046; GO:0051225; GO:0051932; GO:0048489,"aster; cell cortex; cell differentiation; cell division; chiasma assembly; condensed chromosome kinetochore; embryo development ending in birth or egg hatching; engulfment of apoptotic cell; establishment of mitotic spindle orientation; kinetochore; locomotion; microtubule; microtubule associated complex; microtubule organizing center; microtubule-based movement; mitotic centrosome separation; nervous system development; oogenesis; perinuclear region of cytoplasm; pronuclear migration; spindle assembly; synaptic transmission, GABAergic; synaptic vesicle transport",PF08513;PF00400;,,,,,,,,,LIS1_CAEEL,Caenorhabditis elegans,"cell division [GO:0051301]; chiasma assembly [GO:0051026]; embryo development ending in birth or egg hatching [GO:0009792]; engulfment of apoptotic cell [GO:0043652]; establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; locomotion [GO:0040011]; microtubule-based movement [GO:0007018]; mitotic centrosome separation [GO:0007100]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; pronuclear migration [GO:0035046]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; spindle assembly [GO:0051225]; synaptic transmission, GABAergic [GO:0051932]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]" comp98577_c0_seq1,298,42.2819,0.31944804,10,0,,2.00E-21,Q5R9W4,Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9),Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9),GO:0005794; GO:0031902; GO:0006869; GO:0005543,Golgi apparatus; late endosome membrane; lipid transport; phospholipid binding,PF01237;PF00169;,,,,,,,,,OSBL9_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),lipid transport [GO:0006869] comp98587_c1_seq1,1187,46.7565,1.0674001,8,264,,2.00E-10,H2A0M0,Asparagine-rich protein (Prism uncharacterized shell protein 1) (PUSP1),Asparagine-rich protein (Prism uncharacterized shell protein 1) (PUSP1),GO:0005576,extracellular region,,,,,,,,,,NRP_PINMG,Pinctada margaritifera (Black-lipped pearl oyster), comp9858_c0_seq1,206,29.6117,0.45495578,4,0,,,,,,,,,,,1.00E-11,ruditapes_c11534,,,,,,, comp98595_c0_seq1,215,67.907,1.02566321,0,10,,3.00E-07,O07550,Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI (EC 3.6.3.-),Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI (EC 3.6.3.-),GO:0005524; GO:0042626; GO:0016021; GO:0005886; GO:0046677,"ATP binding; ATPase activity, coupled to transmembrane movement of substances; integral to membrane; plasma membrane; response to antibiotic",PF00664;PF00005;,,,,,,,,,YHEI_BACSU,Bacillus subtilis (strain 168),response to antibiotic [GO:0046677] comp98611_c0_seq1,402,43.0348,0.6148443,0,10,,7.00E-12,Q8MV48,N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2),GO:0000139; GO:0005795; GO:0016021; GO:0009312; GO:0004653; GO:0006486,Golgi membrane; Golgi stack; integral to membrane; oligosaccharide biosynthetic process; polypeptide N-acetylgalactosaminyltransferase activity; protein glycosylation,PF00535;PF00652;,,,,,,,,,GALT7_DROME,Drosophila melanogaster (Fruit fly),oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] comp98620_c0_seq1,583,40.8233,0.75212342,4,44,,3.00E-43,Q5REH2,Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 6) (DHHC-6),Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 6) (DHHC-6),GO:0005789; GO:0016021; GO:0016746; GO:0008270,"endoplasmic reticulum membrane; integral to membrane; transferase activity, transferring acyl groups; zinc ion binding",PF07653;PF01529;,1.00E-32,CHOYP_LOC100373598.1.1,,,,,,,ZDHC6_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein palmitoylation [GO:0018345] comp98633_c1_seq1,368,45.6522,0.90181805,13,0,,1.00E-27,Q5RJI4,"Protein kinase domain-containing protein, cytoplasmic (EC 2.7.-.-) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)","Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)",GO:0005524; GO:0005794; GO:0030282; GO:0030154; GO:0048566; GO:0048286; GO:0035264; GO:0042997; GO:0060021; GO:0030501; GO:0032332; GO:0004672; GO:0015031; GO:0001501,ATP binding; Golgi apparatus; bone mineralization; cell differentiation; embryonic digestive tract development; lung alveolus development; multicellular organism growth; negative regulation of Golgi to plasma membrane protein transport; palate development; positive regulation of bone mineralization; positive regulation of chondrocyte differentiation; protein kinase activity; protein transport; skeletal system development,PF12260;,,,,,,,,,PKDCC_MOUSE,Mus musculus (Mouse),bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; palate development [GO:0060021]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; skeletal system development [GO:0001501] comp98637_c0_seq1,602,40.0332,0.66639222,22,21,,2.00E-29,Q0P5H8,Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein,Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein,GO:0016021; GO:0006986; GO:0007283,integral to membrane; response to unfolded protein; spermatogenesis,PF00240;,5.00E-17,CHOYP_HERP2.1.1,,,,,,,HERP2_BOVIN,Bos taurus (Bovine),response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283] comp98649_c0_seq2,555,47.027,0.46130291,8,10,,1.00E-21,Q4KMD7,Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52),Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52),GO:0005524; GO:0050265; GO:0003730; GO:0006379; GO:0006378; GO:0046872; GO:0016607; GO:0005730; GO:0004652; GO:0016180,ATP binding; RNA uridylyltransferase activity; mRNA 3'-UTR binding; mRNA cleavage; mRNA polyadenylation; metal ion binding; nuclear speck; nucleolus; polynucleotide adenylyltransferase activity; snRNA processing,PF03828;PF00076;,,,,,,,,,STPAP_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; snRNA processing [GO:0016180] comp98655_c2_seq1,606,45.7096,0.69879834,21,39,,7.00E-13,Q69Z36,RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3),RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3),GO:0003723; GO:0000932; GO:0005634; GO:0008270,RNA binding; cytoplasmic mRNA processing body; nucleus; zinc ion binding,PF00013;,5.00E-11,CHOYP_MEX3B.1.1,,,,,,,MEX3B_MOUSE,Mus musculus (Mouse),positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phagocytosis [GO:0050766]; protein localization to cell cortex [GO:0072697] comp98675_c1_seq1,254,60.6299,1.18118146,0,9,,3.00E-07,Q45827,Uncharacterized sensor-like histidine kinase Caur_0899 (EC 2.7.13.-),Uncharacterized sensor-like histidine kinase Caur_0899 (EC 2.7.13.-),GO:0005524; GO:0016021; GO:0000155; GO:0005886; GO:0023014,ATP binding; integral to membrane; phosphorelay sensor kinase activity; plasma membrane; signal transduction by phosphorylation,PF13492;PF02518;PF07730;,,,,,,,,,Y899_CHLAA,Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl), comp98681_c0_seq1,428,41.5888,0.88854854,7,9,,,,,,,,,2.00E-45,CHOYP_LOC100368365.2.2,,,,,,,,, comp98689_c0_seq1,268,43.6567,0.86622986,0,19,,4.00E-09,Q54HX8,Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog),Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog),,,PF10601;,,,,,,,,,LITAH_DICDI,Dictyostelium discoideum (Slime mold), comp9870_c0_seq1,313,41.853,0.44857601,8,3,,,,,,,,,3.00E-11,CHOYP_BRAFLDRAFT_216407.1.1,,,,,,,,, comp98716_c0_seq1,511,45.4012,0.65076885,23,45,,8.00E-13,Q9ULM0,Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1),Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1),GO:0005856; GO:0005543,cytoskeleton; phospholipid binding,PF00373;PF00784;PF00169;,4.00E-31,CHOYP_MYO22.2.2,,,,,,,PKHH1_HUMAN,Homo sapiens (Human), comp98720_c0_seq2,465,37.8495,0.48146936,25,22,,4.00E-07,Q6DFT6,Serine palmitoyltransferase small subunit A (Small subunit of serine palmitoyltransferase A) (ssSPTa),Serine palmitoyltransferase small subunit A (Small subunit of serine palmitoyltransferase A) (ssSPTa),GO:0016021; GO:0017059; GO:0006665,integral to membrane; serine C-palmitoyltransferase complex; sphingolipid metabolic process,PF11779;,,,,,,,,,SPTSA_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),sphingolipid metabolic process [GO:0006665] comp98729_c0_seq1,1007,42.999,0.56021602,7,0,,1.00E-23,Q24143,Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1),Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1),GO:0000977; GO:0042632; GO:0004879; GO:0005634; GO:0070873; GO:0042594; GO:0003707; GO:0070328; GO:0008270,RNA polymerase II regulatory region sequence-specific DNA binding; cholesterol homeostasis; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; regulation of glycogen metabolic process; response to starvation; steroid hormone receptor activity; triglyceride homeostasis; zinc ion binding,PF00104;PF00105;,8.00E-24,CHOYP_ISCW_ISCW009328.1.2,,,,,,,HR96_DROME,Drosophila melanogaster (Fruit fly),"cholesterol homeostasis [GO:0042632]; regulation of glucose metabolic process [GO:0010906]; regulation of glycogen metabolic process [GO:0070873]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to starvation [GO:0042594]; steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]" comp98729_c0_seq2,1040,42.3077,0.55995583,0,7,,1.00E-23,Q24143,Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1),Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1),GO:0000977; GO:0042632; GO:0004879; GO:0005634; GO:0070873; GO:0042594; GO:0003707; GO:0070328; GO:0008270,RNA polymerase II regulatory region sequence-specific DNA binding; cholesterol homeostasis; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; nucleus; regulation of glycogen metabolic process; response to starvation; steroid hormone receptor activity; triglyceride homeostasis; zinc ion binding,PF00104;PF00105;,8.00E-24,CHOYP_ISCW_ISCW009328.2.2,,,,,,,HR96_DROME,Drosophila melanogaster (Fruit fly),"cholesterol homeostasis [GO:0042632]; regulation of glucose metabolic process [GO:0010906]; regulation of glycogen metabolic process [GO:0070873]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to starvation [GO:0042594]; steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]" comp98732_c0_seq2,779,42.4904,0.20309511,13,12,,9.00E-10,Q6P4S8,Integrator complex subunit 1 (Int1),Integrator complex subunit 1 (Int1),GO:0034474; GO:0001833; GO:0016021; GO:0032039; GO:0043066; GO:0043154; GO:0031965; GO:0005634,U2 snRNA 3'-end processing; inner cell mass cell proliferation; integral to membrane; integrator complex; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nuclear membrane; nucleus,PF12432;,,,,,,,,,INT1_MOUSE,Mus musculus (Mouse),blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] comp98737_c0_seq1,523,41.8738,0.87406491,21,64,,3.00E-50,Q8BVI5,Syntaxin-16,Syntaxin-16,GO:0005794; GO:0000139; GO:0016021; GO:0006886; GO:0042147,"Golgi apparatus; Golgi membrane; integral to membrane; intracellular protein transport; retrograde transport, endosome to Golgi",PF05739;PF00804;,4.00E-56,CHOYP_LOC100372071.1.1,,,,,,,STX16_MOUSE,Mus musculus (Mouse),"Golgi ribbon formation [GO:0090161]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]" comp98749_c0_seq1,792,42.4242,0.39340956,21,64,,5.00E-57,Q6NXW6,Cell cycle checkpoint protein RAD17,Cell cycle checkpoint protein RAD17,GO:0005524; GO:0000077; GO:0006281; GO:0000781; GO:0007093; GO:0007275; GO:0008156; GO:0017111; GO:0005634; GO:0042325; GO:0006974,"ATP binding; DNA damage checkpoint; DNA repair; chromosome, telomeric region; mitotic cell cycle checkpoint; multicellular organismal development; negative regulation of DNA replication; nucleoside-triphosphatase activity; nucleus; regulation of phosphorylation; response to DNA damage stimulus",,8.00E-48,CHOYP_LOC582037.1.1,,,,,,,RAD17_MOUSE,Mus musculus (Mouse),cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; mitotic cell cycle checkpoint [GO:0007093]; multicellular organism development [GO:0007275]; negative regulation of DNA replication [GO:0008156]; regulation of phosphorylation [GO:0042325] comp9874_c0_seq1,500,40.4,0.39325118,8,0,,6.00E-15,A4IHW3,Probable UDP-sugar transporter protein SLC35A4 (Solute carrier family 35 member A4),Probable UDP-sugar transporter protein SLC35A4 (Solute carrier family 35 member A4),GO:0000139; GO:0016021; GO:0005338; GO:0015780; GO:0005351,Golgi membrane; integral to membrane; nucleotide-sugar transmembrane transporter activity; nucleotide-sugar transport; sugar:hydrogen symporter activity,PF04142;,,,,,,,,,S35A4_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp98761_c0_seq2,417,38.8489,0.38513735,3,26,,2.00E-13,Q2KIL7,R3H domain-containing protein 4,R3H domain-containing protein 4,GO:0003676; GO:0005634,nucleic acid binding; nucleus,PF01424;PF13902;,,,2.00E-51,ruditapes2_c1879,,,,,R3HD4_BOVIN,Bos taurus (Bovine), comp98765_c0_seq1,461,40.1302,0.99641015,15,0,,8.00E-07,Q9NSD4,Zinc finger protein 275,Zinc finger protein 275,GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN275_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp98789_c0_seq1,1541,41.0772,0.33969533,108,145,,1.00E-16,Q9I7U4,Titin (D-Titin) (Kettin),Titin (D-Titin) (Kettin),GO:0030018; GO:0003779; GO:0051301; GO:0000794; GO:0040011; GO:0007498; GO:0005875; GO:0007076; GO:0016203; GO:0007520; GO:0035206; GO:0045214; GO:0007062; GO:0007519; GO:0007525; GO:0008307; GO:0007522,Z disc; actin binding; cell division; condensed nuclear chromosome; locomotion; mesoderm development; microtubule associated complex; mitotic chromosome condensation; muscle attachment; myoblast fusion; regulation of hemocyte proliferation; sarcomere organization; sister chromatid cohesion; skeletal muscle tissue development; somatic muscle development; structural constituent of muscle; visceral muscle development,PF06582;PF00041;PF07679;PF00018;,7.00E-40,CHOYP_PHUM_PHUM226120.5.7,,,,,,,TITIN_DROME,Drosophila melanogaster (Fruit fly),cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522] comp98795_c0_seq1,1273,36.1351,0.48696613,22,114,,5.00E-40,P51523,Zinc finger protein 84 (Zinc finger protein HPF2),Zinc finger protein 84 (Zinc finger protein HPF2),GO:0003677; GO:0005634; GO:0006355; GO:0006351; GO:0008270,"DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent; zinc ion binding",PF01352;PF00096;PF13912;,,,,,,,,,ZNF84_HUMAN,Homo sapiens (Human),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp98830_c1_seq1,307,43.9739,0.76583091,3,11,,9.00E-24,Q0VG85,Coiled-coil domain-containing protein 162 (Protein CCDC162P),Coiled-coil domain-containing protein 162 (Protein CCDC162P),,,,6.00E-13,CHOYP_LOC579367.1.1,,,,,,,CC162_MOUSE,Mus musculus (Mouse), comp98831_c0_seq1,732,43.4426,0.4059343,15,34,,5.00E-91,Q5RCB9,"Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)","Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)",GO:0000139; GO:0008375; GO:0016021; GO:0006486,Golgi membrane; acetylglucosaminyltransferase activity; integral to membrane; protein glycosylation,PF03071;,7.00E-36,CHOYP_POMGNT1.1.1,,,,,,,PMGT1_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein glycosylation [GO:0006486] comp98839_c0_seq1,366,45.082,0.53939262,0,51,,2.00E-12,O09164,Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1),Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1),GO:0005507; GO:0005829; GO:0031012; GO:0005615; GO:0005739; GO:0005634; GO:0019430; GO:0046688; GO:0001666; GO:0004784; GO:0005802; GO:0008270,copper ion binding; cytosol; extracellular matrix; extracellular space; mitochondrion; nucleus; removal of superoxide radicals; response to copper ion; response to hypoxia; superoxide dismutase activity; trans-Golgi network; zinc ion binding,PF00080;,,,,,,,,,SODE_MOUSE,Mus musculus (Mouse),response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302] comp98856_c0_seq1,530,35.4717,0.53528416,0,0,,3.00E-09,Q7ZWE7,Nucleolar protein 12,Nucleolar protein 12,GO:0005730; GO:0019843,nucleolus; rRNA binding,PF09805;,,,,,,,,,NOL12_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio), comp98856_c0_seq2,578,35.4671,0.49360762,0,11,,4.00E-11,Q9UGY1,Nucleolar protein 12,Nucleolar protein 12,GO:0005730; GO:0019843,nucleolus; rRNA binding,PF09805;,,,,,,,,,NOL12_HUMAN,Homo sapiens (Human), comp98867_c0_seq1,342,54.9708,1.12778742,1,5,,4.00E-19,A0QHM5,Lipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II),Lipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II),GO:0004190; GO:0016021; GO:0005886; GO:0006508,aspartic-type endopeptidase activity; integral to membrane; plasma membrane; proteolysis,PF01252;,,,,,,,,,LSPA_MYCA1,Mycobacterium avium (strain 104), comp98878_c0_seq1,396,44.1919,0.77802952,1,30,,4.00E-18,Q9BYK8,"Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)","Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)",GO:0005524; GO:0003677; GO:0044255; GO:0004386; GO:0030374; GO:0046872; GO:0005654; GO:0045944; GO:0044281; GO:0006351,"ATP binding; DNA binding; cellular lipid metabolic process; helicase activity; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; nucleoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; transcription, DNA-dependent",,2.00E-20,CHOYP_LOC100369525.2.2,,,,,,,PR285_HUMAN,Homo sapiens (Human),"cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]" comp98891_c0_seq1,372,46.7742,0.49338981,1,36,,1.00E-14,P28685,Contactin-2 (Axonin-1),Contactin-2 (Axonin-1),GO:0031225; GO:0007158; GO:0005886,anchored to membrane; neuron cell-cell adhesion; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN2_CHICK,Gallus gallus (Chicken),axon guidance [GO:0007411]; central nervous system development [GO:0007417]; neuron cell-cell adhesion [GO:0007158]; neuron migration [GO:0001764]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205] comp98891_c1_seq1,474,44.7257,0.42278782,0,0,,2.00E-10,Q8IWV2,Contactin-4 (Brain-derived immunoglobulin superfamily protein 2) (BIG-2),Contactin-4 (Brain-derived immunoglobulin superfamily protein 2) (BIG-2),GO:0031225; GO:0030424; GO:0007411; GO:0007413; GO:0007420; GO:0005576; GO:0045665; GO:0007158; GO:0005886; GO:0048167,anchored to membrane; axon; axon guidance; axonal fasciculation; brain development; extracellular region; negative regulation of neuron differentiation; neuron cell-cell adhesion; plasma membrane; regulation of synaptic plasticity,PF00041;PF07679;,,,,,,,,,CNTN4_HUMAN,Homo sapiens (Human),axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; neuron cell-cell adhesion [GO:0007158]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167] comp98891_c2_seq1,391,46.8031,0.65552268,0,30,,1.00E-12,Q7ZW34,Contactin-5,Contactin-5,GO:0031225; GO:0007155; GO:0005886,anchored to membrane; cell adhesion; plasma membrane,PF00041;PF07679;,,,,,,,,,CNTN5_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605] comp98903_c0_seq1,395,30.1266,0.56250361,13,38,,,,,,,,,,,2.00E-11,ruditapes_c17851,,,,,,, comp98913_c1_seq1,332,45.7831,0.77207763,2,31,,8.00E-31,Q96PE3,"Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)","Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)",GO:0005829; GO:0043647; GO:0016316; GO:0036092; GO:0034597; GO:0007165,"cytosol; inositol phosphate metabolic process; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; phosphatidylinositol-3-phosphate biosynthetic process; phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity; signal transduction",,,,,,,,,,INP4A_HUMAN,Homo sapiens (Human),inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol biosynthetic process [GO:0006661]; signal transduction [GO:0007165] comp98918_c0_seq1,603,40.9619,0.80159477,7,46,,3.00E-71,Q09221,Copine family protein 2,Copine family protein 2,,,PF07002;,3.00E-39,CHOYP_LOC100369190.1.1,2.00E-83,ruditapes2_c791,,,,,CPNA2_CAEEL,Caenorhabditis elegans, comp98922_c0_seq1,398,40.4523,0.68046941,0,74,,6.00E-12,A0FGR9,Extended synaptotagmin-3 (E-Syt3) (Chr3Syt),Extended synaptotagmin-3 (E-Syt3) (Chr3Syt),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF00168;PF17047;,,,,,,,,,ESYT3_HUMAN,Homo sapiens (Human),lipid transport [GO:0006869] comp98922_c1_seq1,1086,41.8969,1.23942978,0,163,,1.00E-53,Q9BSW7,Synaptotagmin-17 (Protein B/K) (Synaptotagmin XVII) (SytXVII),Synaptotagmin-17 (Protein B/K) (Synaptotagmin XVII) (SytXVII),GO:0016020; GO:0008021; GO:0005802; GO:0005215,membrane; synaptic vesicle; trans-Golgi network; transporter activity,PF00168;,2.00E-64,CHOYP_SYT17.1.1,,,,,,,SYT17_HUMAN,Homo sapiens (Human),calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; positive regulation of dendrite extension [GO:1903861]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906] comp98928_c3_seq1,425,45.6471,0.3625552,12,13,,7.00E-21,Q9UKK3,Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP),GO:0003677; GO:0006281; GO:0003950; GO:0008219; GO:0005737; GO:0019899; GO:0006954; GO:0005634; GO:0006471; GO:0042493; GO:0030529; GO:0005876; GO:0006810,DNA binding; DNA repair; NAD+ ADP-ribosyltransferase activity; cell death; cytoplasm; enzyme binding; inflammatory response; nucleus; protein ADP-ribosylation; response to drug; ribonucleoprotein complex; spindle microtubule; transport,PF00533;PF00644;PF08487;PF00092;,6.00E-21,CHOYP_LOC100373327.1.13,,,,,,,PARP4_HUMAN,Homo sapiens (Human),cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810] comp98943_c0_seq2,247,42.915,0.35632768,7,13,,1.00E-09,Q9NS93,Transmembrane 7 superfamily member 3 (Seven span transmembrane protein),Transmembrane 7 superfamily member 3 (Seven span transmembrane protein),GO:0016021; GO:0005886,integral to membrane; plasma membrane,PF13886;,,,,,,,,,TM7S3_HUMAN,Homo sapiens (Human), comp9894_c0_seq1,238,42.0168,0.57568258,4,0,,,,,,,,,,,3.00E-19,ruditapes2_c2711,,,,,,, comp98958_c0_seq1,444,42.7928,0.34549865,12,33,,2.00E-21,O88984,Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP),Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP),GO:0003723; GO:0005737; GO:0006406; GO:0016607; GO:0000166,RNA binding; cytoplasm; mRNA export from nucleus; nuclear speck; nucleotide binding,PF02136;PF09162;PF03943;,1.00E-11,CHOYP_NXF1.1.2,,,,,,,NXF1_RAT,Rattus norvegicus (Rat),poly(A)+ mRNA export from nucleus [GO:0016973] comp99001_c0_seq1,360,39.1667,0.581091,8,33,,9.00E-18,Q9NRM2,Zinc finger protein 277 (Nuclear receptor-interacting factor 4),Zinc finger protein 277 (Nuclear receptor-interacting factor 4),GO:0003677; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF12756;,,,,,,,,,ZN277_HUMAN,Homo sapiens (Human),"cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp99001_c1_seq1,315,40.9524,0.45577382,8,5,,,,,,,,,4.00E-15,CHOYP_LOC100702329.1.1,,,,,,,,, comp9903_c0_seq1,384,42.9688,0.51001229,9,0,,4.00E-15,Q55E58,Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1),GO:0005524; GO:0005525; GO:0042641; GO:0000281; GO:0004721; GO:0006470; GO:0004674; GO:0007264,ATP binding; GTP binding; actomyosin; mitotic cytokinesis; phosphoprotein phosphatase activity; protein dephosphorylation; protein serine/threonine kinase activity; small GTPase mediated signal transduction,PF16095;PF06602;PF07714;PF08477;,8.00E-19,CHOYP_TRIADDRAFT_57945.1.3,,,,,,,PATS1_DICDI,Dictyostelium discoideum (Slime mold),mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176] comp99052_c0_seq1,688,43.8953,0.48401929,14,31,,4.00E-83,P62257,Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H),Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H),GO:0005524; GO:0070979; GO:0070936; GO:0004842,ATP binding; protein K11-linked ubiquitination; protein K48-linked ubiquitination; ubiquitin-protein ligase activity,PF00179;,9.00E-110,CHOYP_CPIPJ_CPIJ015105.1.1,,,,,,,UBE2H_MOUSE,Mus musculus (Mouse),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936] comp99053_c1_seq1,370,49.4595,0.97515647,8,7,,4.00E-41,O18927,Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13),Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13),GO:0005509; GO:0030574; GO:0004222; GO:0005578; GO:0006508; GO:0008270,calcium ion binding; collagen catabolic process; metalloendopeptidase activity; proteinaceous extracellular matrix; proteolysis; zinc ion binding,PF00045;PF00413;PF01471;,7.00E-26,CHOYP_LOC100369238.1.1,,,,,,,MMP13_HORSE,Equus caballus (Horse),bone morphogenesis [GO:0060349]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617] comp99054_c0_seq1,498,43.3735,0.25677634,7,5,,8.00E-14,Q0P4U8,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1),SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1),GO:0005524; GO:0003677; GO:0008094; GO:0036310; GO:0016568; GO:0004386; GO:0005634; GO:0006357,ATP binding; DNA binding; DNA-dependent ATPase activity; annealing helicase activity; chromatin modification; helicase activity; nucleus; regulation of transcription from RNA polymerase II promoter,PF07443;PF00271;PF00176;,,,,,,,,,SMAL1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),angiogenesis [GO:0001525]; cartilage development [GO:0051216]; developmental growth [GO:0048589]; DNA metabolic process [GO:0006259]; embryonic body morphogenesis [GO:0010172]; hemopoiesis [GO:0030097]; mitotic cell cycle [GO:0000278]; regulation of transcription from RNA polymerase II promoter [GO:0006357] comp99055_c0_seq1,420,43.3333,0.57279236,7,6,,9.00E-32,Q96P48,"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)","Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)",GO:0008060; GO:0005794; GO:0032580; GO:0005100; GO:0030037; GO:0005829; GO:0051497; GO:0005547; GO:0005886; GO:0043089; GO:0051491; GO:0032312; GO:0008360; GO:0051270; GO:0007264; GO:0008270,"ARF GTPase activator activity; Golgi apparatus; Golgi cisterna membrane; Rho GTPase activator activity; actin filament reorganization involved in cell cycle; cytosol; negative regulation of stress fiber assembly; phosphatidylinositol-3,4,5-trisphosphate binding; plasma membrane; positive regulation of Cdc42 GTPase activity; positive regulation of filopodium assembly; regulation of ARF GTPase activity; regulation of cell shape; regulation of cellular component movement; small GTPase mediated signal transduction; zinc ion binding",PF01412;PF00169;PF00788;PF00620;PF00536;,8.00E-13,CHOYP_LOC100639879.1.1,,,,,,,ARAP1_HUMAN,Homo sapiens (Human),actin filament reorganization involved in cell cycle [GO:0030037]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of receptor recycling [GO:0001921]; regulation of cell shape [GO:0008360]; regulation of cellular component movement [GO:0051270]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] comp99057_c0_seq1,874,45.5378,0.9725919,27,80,,2.00E-46,Q3T052,Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4),Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4),GO:0006953; GO:0005576; GO:0030212; GO:0004867,acute-phase response; extracellular region; hyaluronan metabolic process; serine-type endopeptidase inhibitor activity,PF06668;PF08487;PF00092;,2.00E-25,CHOYP_ITIH3.1.3,,,,,,,ITIH4_BOVIN,Bos taurus (Bovine),acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212] comp99060_c0_seq1,368,33.6957,0.28865924,19,116,,,,,,,,,1.00E-15,CHOYP_contig_054187,,,,,,,,, comp99061_c0_seq1,225,39.5556,0.3770931,1,6,,1.00E-16,P48037,Annexin A6 (Annexin VI) (Annexin-6) (Calcium-binding protein 65/67) (CBP 65/67),Annexin A6 (Annexin VI) (Annexin-6) (Calcium-binding protein 65/67) (CBP 65/67),GO:0016324; GO:0005509; GO:0005544; GO:0005737; GO:0042470; GO:0043234; GO:0046903,apical plasma membrane; calcium ion binding; calcium-dependent phospholipid binding; cytoplasm; melanosome; protein complex; secretion,PF00191;,,,,,,,,,ANXA6_RAT,Rattus norvegicus (Rat),secretion [GO:0046903] comp99061_c1_seq2,296,48.9865,0.2864616,2,3,,5.00E-18,Q4R5L5,Annexin A7 (Annexin VII) (Annexin-7),Annexin A7 (Annexin VII) (Annexin-7),GO:0005509; GO:0005544,calcium ion binding; calcium-dependent phospholipid binding,PF00191;,,,,,,,,,ANXA7_MACFA,Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), comp99091_c0_seq1,439,41.6856,0.5312754,14,65,,7.00E-56,P40692,DNA mismatch repair protein Mlh1 (MutL protein homolog 1),DNA mismatch repair protein Mlh1 (MutL protein homolog 1),GO:0005524; GO:0016887; GO:0032389; GO:0032390; GO:0005712; GO:0006303; GO:0032137; GO:0008630; GO:0045190; GO:0001673; GO:0007060; GO:0043060; GO:0006298; GO:0045950; GO:0000289; GO:0048477; GO:0007131; GO:0000712; GO:0016446; GO:0007283; GO:0051257; GO:0007129; GO:0000795,ATP binding; ATPase activity; MutLalpha complex; MutLbeta complex; chiasma; double-strand break repair via nonhomologous end joining; guanine/thymine mispair binding; intrinsic apoptotic signaling pathway in response to DNA damage; isotype switching; male germ cell nucleus; male meiosis chromosome segregation; meiotic metaphase I plate congression; mismatch repair; negative regulation of mitotic recombination; nuclear-transcribed mRNA poly(A) tail shortening; oogenesis; reciprocal meiotic recombination; resolution of meiotic recombination intermediates; somatic hypermutation of immunoglobulin genes; spermatogenesis; spindle midzone assembly involved in meiosis; synapsis; synaptonemal complex,PF01119;PF16413;,6.00E-21,CHOYP_MLH1.1.1,,,,,,,MLH1_HUMAN,Homo sapiens (Human),double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]; synapsis [GO:0007129] comp99097_c0_seq1,621,48.6312,0.47577176,11,22,,1.00E-49,A6QM06,Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein),GO:0012507; GO:0000139; GO:0008203; GO:0005789; GO:0016021,ER to Golgi transport vesicle membrane; Golgi membrane; cholesterol metabolic process; endoplasmic reticulum membrane; integral to membrane,PF12349;PF00400;,3.00E-20,CHOYP_BRAFLDRAFT_118545.2.2,,,,,,,SCAP_BOVIN,Bos taurus (Bovine),cholesterol metabolic process [GO:0008203]; SREBP signaling pathway [GO:0032933] comp99104_c0_seq1,287,38.3275,0.94737992,1,28,,1.00E-24,Q5RF84,Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2),Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2),GO:0005524; GO:0030433; GO:0070936; GO:0018279; GO:0004842,ATP binding; ER-associated protein catabolic process; protein K48-linked ubiquitination; protein N-linked glycosylation via asparagine; ubiquitin-protein ligase activity,PF00179;,5.00E-26,CHOYP_UB2G2.1.1,,,,,,,UB2G2_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein K48-linked ubiquitination [GO:0070936]; protein N-linked glycosylation via asparagine [GO:0018279] comp99118_c0_seq1,436,45.4128,0.6805476,5,41,,1.00E-50,P53603,Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)],Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)],GO:0005794; GO:0005814; GO:0005542; GO:0030412; GO:0030409; GO:0019556; GO:0019557; GO:0035999,Golgi apparatus; centriole; folic acid binding; formimidoyltetrahydrofolate cyclodeaminase activity; glutamate formimidoyltransferase activity; histidine catabolic process to glutamate and formamide; histidine catabolic process to glutamate and formate; tetrahydrofolate interconversion,PF02971;PF04961;PF07837;,3.00E-56,CHOYP_BRAFLDRAFT_125780.1.1,,,,,,,FTCD_PIG,Sus scrofa (Pig),histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999] comp99126_c0_seq1,395,30.1266,2.13266673,13,32,,,,,,,,,,,2.00E-12,ruditapes_lrc23864,,,,,,, comp99129_c0_seq1,229,44.5415,0.97609886,10,13,,6.00E-09,Q9UL36,Zinc finger protein 236,Zinc finger protein 236,GO:0003677; GO:0071333; GO:0046872; GO:0005634; GO:0003700; GO:0006351,"DNA binding; cellular response to glucose stimulus; metal ion binding; nucleus; sequence-specific DNA binding transcription factor activity; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZN236_HUMAN,Homo sapiens (Human),"cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp99156_c0_seq1,1426,35.9748,1.02314244,127,4,,4.00E-14,P30543,Adenosine receptor A2a,Adenosine receptor A2a,GO:0001609; GO:0000139; GO:0007189; GO:0051393; GO:0048143; GO:0032279; GO:0030673; GO:0030425; GO:0042755; GO:0016021; GO:0007626; GO:0046636; GO:0008285; GO:0043154; GO:0050728; GO:0040013; GO:0043524; GO:0006469; GO:0043116; GO:0048812; GO:0043025; GO:0014057; GO:2001235; GO:0030819; GO:0045938; GO:0014049; GO:0050714; GO:0035815; GO:0032230; GO:0051968; GO:0035810; GO:0014069; GO:0045211; GO:0060134; GO:0048786; GO:0042734; GO:0007205; GO:0051924; GO:0060079; GO:0060080; GO:0051881; GO:0014061; GO:0048167; GO:0006355; GO:0001975; GO:0031000; GO:0042493; GO:0007271; GO:0001963; GO:0035249; GO:0042311,"G-protein coupled adenosine receptor activity; Golgi membrane; adenylate cyclase-activating G-protein coupled receptor signaling pathway; alpha-actinin binding; astrocyte activation; asymmetric synapse; axolemma; dendrite; eating behavior; integral to membrane; locomotory behavior; negative regulation of alpha-beta T cell activation; negative regulation of cell proliferation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of inflammatory response; negative regulation of locomotion; negative regulation of neuron apoptotic process; negative regulation of protein kinase activity; negative regulation of vascular permeability; neuron projection morphogenesis; neuronal cell body; positive regulation of acetylcholine secretion, neurotransmission; positive regulation of apoptotic signaling pathway; positive regulation of cAMP biosynthetic process; positive regulation of circadian sleep/wake cycle, sleep; positive regulation of glutamate secretion; positive regulation of protein secretion; positive regulation of renal sodium excretion; positive regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, glutamatergic; positive regulation of urine volume; postsynaptic density; postsynaptic membrane; prepulse inhibition; presynaptic active zone; presynaptic membrane; protein kinase C-activating G-protein coupled receptor signaling pathway; regulation of calcium ion transport; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential; regulation of mitochondrial membrane potential; regulation of norepinephrine secretion; regulation of synaptic plasticity; regulation of transcription, DNA-dependent; response to amphetamine; response to caffeine; response to drug; synaptic transmission, cholinergic; synaptic transmission, dopaminergic; synaptic transmission, glutamatergic; vasodilation",PF00001;,,,,,,,,,AA2AR_RAT,Rattus norvegicus (Rat),"activation of adenylate cyclase activity [GO:0007190]; adenosine receptor signaling pathway [GO:0001973]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; astrocyte activation [GO:0048143]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; response to alkaloid [GO:0043279]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]" comp99177_c0_seq2,377,34.2175,0.3827875,3,0,,1.00E-07,P97807,"Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) (EF-3)","Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) (EF-3)",GO:0004333; GO:0006106; GO:0048873; GO:0005739; GO:0006099; GO:0045239,fumarate hydratase activity; fumarate metabolic process; homeostasis of number of cells within a tissue; mitochondrion; tricarboxylic acid cycle; tricarboxylic acid cycle enzyme complex,PF10415;PF00206;,,,,,,,,,FUMH_MOUSE,Mus musculus (Mouse),fumarate metabolic process [GO:0006106]; homeostasis of number of cells within a tissue [GO:0048873]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099] comp99197_c1_seq1,410,44.3902,0.61002218,6,30,,5.00E-08,Q9VW71,Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),Fat-like cadherin-related tumor suppressor homolog (Protein kugelei),GO:0009925; GO:0005509; GO:0016339; GO:0050839; GO:0050829; GO:0042247; GO:0030950; GO:0005925; GO:0007440; GO:0007295; GO:0007442; GO:0007156; GO:0005887; GO:0045571; GO:0007424; GO:0045089; GO:0004872; GO:0007431,basal plasma membrane; calcium ion binding; calcium-dependent cell-cell adhesion; cell adhesion molecule binding; defense response to Gram-negative bacterium; establishment of planar polarity of follicular epithelium; establishment or maintenance of actin cytoskeleton polarity; focal adhesion; foregut morphogenesis; growth of a germarium-derived egg chamber; hindgut morphogenesis; homophilic cell adhesion; integral to plasma membrane; negative regulation of imaginal disc growth; open tracheal system development; positive regulation of innate immune response; receptor activity; salivary gland development,PF00028;PF02210;,,,,,,,,,FAT2_DROME,Drosophila melanogaster (Fruit fly),calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431] comp99209_c1_seq1,307,44.6254,0.66667374,25,10,,1.00E-45,A4IH75,Autophagy-related protein 101,Autophagy-related protein 101,GO:0006914; GO:0000407,autophagy; pre-autophagosomal structure,PF07855;,7.00E-31,CHOYP_ATGA1.1.1,,,,,,,ATGA1_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis),autophagosome assembly [GO:0000045] comp99210_c0_seq1,625,41.28,0.42619407,33,31,,2.00E-06,Q8BH60,Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST),Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST),GO:0000139; GO:0006914; GO:0030054; GO:0030425; GO:0044325; GO:0005886; GO:0014069; GO:0045211; GO:0043234; GO:0051260; GO:0015031; GO:0005083; GO:0007289; GO:0045202; GO:0019905; GO:0030140,Golgi membrane; autophagy; cell junction; dendrite; ion channel binding; plasma membrane; postsynaptic density; postsynaptic membrane; protein complex; protein homooligomerization; protein transport; small GTPase regulator activity; spermatid nucleus differentiation; synapse; syntaxin binding; trans-Golgi network transport vesicle,PF00595;,8.00E-15,CHOYP_GOPC.1.1,,,,,,,GOPC_MOUSE,Mus musculus (Mouse),autophagy [GO:0006914]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; spermatid nucleus differentiation [GO:0007289] comp99216_c0_seq1,214,44.8598,0.37343412,4,8,,,,,,,,,7.00E-42,CHOYP_AGAP_AGAP000065.1.1,,,,,,,,, comp99216_c1_seq2,598,44.9833,0.71536824,20,12,,5.00E-99,Q4KUS2,Protein unc-13 homolog A (Munc13-1),Protein unc-13 homolog A (Munc13-1),GO:0050435; GO:0030054; GO:0005737; GO:0019992; GO:0060384; GO:0035556; GO:0046872; GO:0031594; GO:0007528; GO:0001956; GO:0042734; GO:0048172; GO:0035249; GO:0016081; GO:0016188; GO:0016082,"beta-amyloid metabolic process; cell junction; cytoplasm; diacylglycerol binding; innervation; intracellular signal transduction; metal ion binding; neuromuscular junction; neuromuscular junction development; positive regulation of neurotransmitter secretion; presynaptic membrane; regulation of short-term neuronal synaptic plasticity; synaptic transmission, glutamatergic; synaptic vesicle docking involved in exocytosis; synaptic vesicle maturation; synaptic vesicle priming",PF00130;PF00168;PF06292;PF10540;,4.00E-132,CHOYP_LOC100650524.1.2,,,,,,,UN13A_MOUSE,Mus musculus (Mouse),"beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]" comp99216_c2_seq1,268,41.4179,0.44714718,4,0,,6.00E-06,A6N9I4,RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI),RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI),GO:0005509; GO:0030054; GO:0005829; GO:0005085; GO:0043005; GO:0051056; GO:0032587; GO:0007264; GO:0045202,calcium ion binding; cell junction; cytosol; guanyl-nucleotide exchange factor activity; neuron projection; regulation of small GTPase mediated signal transduction; ruffle membrane; small GTPase mediated signal transduction; synapse,PF00130;PF13202;PF00617;PF00618;,,,,,,,,,GRP2_BOVIN,Bos taurus (Bovine),small GTPase mediated signal transduction [GO:0007264] comp99237_c0_seq1,214,47.6636,0.33179737,5,13,,2.00E-11,Q8N475,Follistatin-related protein 5 (Follistatin-like protein 5),Follistatin-related protein 5 (Follistatin-like protein 5),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07648;,,,,,,,,,FSTL5_HUMAN,Homo sapiens (Human), comp99245_c1_seq1,550,47.0909,0.71558678,3,49,,1.00E-38,Q3V6T2,Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1),GO:0006260; GO:0005794; GO:0031929; GO:0003779; GO:0032148; GO:0016477; GO:0016023; GO:0031410; GO:0005829; GO:0005783; GO:0030027; GO:0030032; GO:0061024; GO:0008017; GO:0035091; GO:0005886; GO:0006275; GO:0032956; GO:0042127; GO:0010975,DNA replication; Golgi apparatus; TOR signaling cascade; actin binding; activation of protein kinase B activity; cell migration; cytoplasmic membrane-bounded vesicle; cytoplasmic vesicle; cytosol; endoplasmic reticulum; lamellipodium; lamellipodium assembly; membrane organization; microtubule binding; phosphatidylinositol binding; plasma membrane; regulation of DNA replication; regulation of actin cytoskeleton organization; regulation of cell proliferation; regulation of neuron projection development,PF05622;,5.00E-17,CHOYP_GRDN.5.5,,,,,,,GRDN_HUMAN,Homo sapiens (Human),activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] comp99256_c0_seq1,328,43.9024,0.4592266,6,10,,1.00E-43,Q5R5P0,WASH complex subunit strumpellin,WASH complex subunit strumpellin,GO:0071203,WASH complex,PF10266;,3.00E-29,CHOYP_STRUM.1.1,,,,,,,STRUM_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii),protein transport [GO:0015031] comp99269_c0_seq1,215,63.7209,0.82972346,3,13,,2.00E-16,P32672,Fructose-like permease IIC component 2 (PTS system fructose-like EIIC component 2),Fructose-like permease IIC component 2 (PTS system fructose-like EIIC component 2),GO:0016021; GO:0009401; GO:0005886; GO:0008982; GO:0005351,integral to membrane; phosphoenolpyruvate-dependent sugar phosphotransferase system; plasma membrane; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; sugar:hydrogen symporter activity,,,,,,,,,,PTFC2_ECOLI,Escherichia coli (strain K12),phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401] comp99281_c0_seq1,535,41.8692,0.56089707,20,27,,5.00E-15,Q924W7,Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B),Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B),GO:0017112; GO:0070374,Rab guanyl-nucleotide exchange factor activity; positive regulation of ERK1 and ERK2 cascade,PF03455;PF02141;PF03456;,,,,,,,,,ST5_MOUSE,Mus musculus (Mouse),positive regulation of ERK1 and ERK2 cascade [GO:0070374] comp99295_c3_seq1,233,37.7682,0.12093246,2,5,,3.00E-33,Q6DC39,Desumoylating isopeptidase 2 (DeSI-2) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 1) (Protein FAM152A),Desumoylating isopeptidase 2 (DeSI-2) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 1) (Protein FAM152A),GO:0060027; GO:0005737; GO:0008233; GO:0006508,convergent extension involved in gastrulation; cytoplasm; peptidase activity; proteolysis,PF05903;,4.00E-33,CHOYP_LOC100707081.1.1,,,,,,,DESI2_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),convergent extension involved in gastrulation [GO:0060027] comp99319_c0_seq1,703,49.3599,1.0114963,15,48,,2.00E-31,P05556,Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29),Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29),GO:0030183; GO:0000082; GO:0001669; GO:0003779; GO:0034667; GO:0034678; GO:0034679; GO:0007411; GO:0005604; GO:0007596; GO:0007161; GO:0055007; GO:0001708; GO:0034329; GO:0002042; GO:0009986; GO:0033631; GO:0006874; GO:0006968; GO:0071479; GO:0071260; GO:0071305; GO:0032154; GO:0005737; GO:0009897; GO:0030198; GO:0030175; GO:0005925; GO:0008354; GO:0030056; GO:0007156; GO:0001701; GO:0007229; GO:0014704; GO:0030027; GO:0007159; GO:0050900; GO:0060135; GO:0042470; GO:0045121; GO:0046872; GO:0019048; GO:0035748; GO:2000811; GO:0031345; GO:0008285; GO:0045665; GO:0031594; GO:0042277; GO:0043410; GO:0043065; GO:0030335; GO:0008284; GO:0010811; GO:0045807; GO:0045666; GO:0010976; GO:0050731; GO:0046982; GO:0032594; GO:0055037; GO:0008277; GO:0051726; GO:0050776; GO:0014823; GO:0042493; GO:0034698; GO:0071559; GO:0009615; GO:0001726; GO:0042383; GO:0045214; GO:0070830; GO:0001894; GO:0001618,B cell differentiation; G1/S transition of mitotic cell cycle; acrosomal vesicle; actin binding; alpha3-beta1 integrin complex; alpha8-beta1 integrin complex; alpha9-beta1 integrin complex; axon guidance; basement membrane; blood coagulation; calcium-independent cell-matrix adhesion; cardiac muscle cell differentiation; cell fate specification; cell junction assembly; cell migration involved in sprouting angiogenesis; cell surface; cell-cell adhesion mediated by integrin; cellular calcium ion homeostasis; cellular defense response; cellular response to ionizing radiation; cellular response to mechanical stimulus; cellular response to vitamin D; cleavage furrow; cytoplasm; external side of plasma membrane; extracellular matrix organization; filopodium; focal adhesion; germ cell migration; hemidesmosome; homophilic cell adhesion; in utero embryonic development; integrin-mediated signaling pathway; intercalated disc; lamellipodium; leukocyte cell-cell adhesion; leukocyte migration; maternal process involved in female pregnancy; melanosome; membrane raft; metal ion binding; modulation by virus of host morphology or physiology; myelin sheath abaxonal region; negative regulation of anoikis; negative regulation of cell projection organization; negative regulation of cell proliferation; negative regulation of neuron differentiation; neuromuscular junction; peptide binding; positive regulation of MAPK cascade; positive regulation of apoptotic process; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of cell-substrate adhesion; positive regulation of endocytosis; positive regulation of neuron differentiation; positive regulation of neuron projection development; positive regulation of peptidyl-tyrosine phosphorylation; protein heterodimerization activity; protein transport within lipid bilayer; recycling endosome; regulation of G-protein coupled receptor protein signaling pathway; regulation of cell cycle; regulation of immune response; response to activity; response to drug; response to gonadotropin stimulus; response to transforming growth factor beta stimulus; response to virus; ruffle; sarcolemma; sarcomere organization; tight junction assembly; tissue homeostasis; virus receptor activity,PF07974;PF08725;PF07965;PF00362;,,,,,,,,,ITB1_HUMAN,Homo sapiens (Human),axon extension [GO:0048675]; B cell differentiation [GO:0030183]; bicellular tight junction assembly [GO:0070830]; calcium-independent cell-matrix adhesion [GO:0007161]; cardiac muscle cell differentiation [GO:0055007]; cell-cell adhesion mediated by integrin [GO:0033631]; cell fate specification [GO:0001708]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-substrate adhesion [GO:0031589]; cellular calcium ion homeostasis [GO:0006874]; cellular defense response [GO:0006968]; cellular response to ionizing radiation [GO:0071479]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to mechanical stimulus [GO:0071260]; cellular response to vitamin D [GO:0071305]; dendrite morphogenesis [GO:0048813]; extracellular matrix organization [GO:0030198]; formation of radial glial scaffolds [GO:0021943]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell migration [GO:0008354]; heterotypic cell-cell adhesion [GO:0034113]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; maternal process involved in female pregnancy [GO:0060135]; mesodermal cell differentiation [GO:0048333]; negative regulation of anoikis [GO:2000811]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of endocytosis [GO:0045807]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein transport within lipid bilayer [GO:0032594]; receptor internalization [GO:0031623]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of immune response [GO:0050776]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to gonadotropin [GO:0034698]; response to transforming growth factor beta [GO:0071559]; sarcomere organization [GO:0045214]; tissue homeostasis [GO:0001894]; visual learning [GO:0008542] comp99332_c0_seq1,208,45.6731,1.52003513,0,3,,2.00E-12,Q5H8C1,FRAS1-related extracellular matrix protein 1 (Protein QBRICK),FRAS1-related extracellular matrix protein 1 (Protein QBRICK),GO:0005604; GO:0030246; GO:0007154; GO:0007160; GO:0097094; GO:0016021; GO:0046872,basement membrane; carbohydrate binding; cell communication; cell-matrix adhesion; craniofacial suture morphogenesis; integral to membrane; metal ion binding,PF03160;PF00059;,,,,,,,,,FREM1_HUMAN,Homo sapiens (Human),cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] comp99341_c0_seq1,883,42.2424,0.45866541,15,135,,4.00E-45,Q6P6R0,Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit),Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit),GO:0005261; GO:0016021,cation channel activity; integral to membrane,,2.00E-61,CHOYP_NEMVEDRAFT_V1G189239.1.1,,,,,,,LFG1_RAT,Rattus norvegicus (Rat),endoplasmic reticulum calcium ion homeostasis [GO:0032469]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236] comp99342_c0_seq2,1136,40.4049,0.756157,5,29,,2.00E-98,Q08BI9,"Calcium uniporter protein, mitochondrial (Coiled-coil domain-containing protein 109A)","Calcium uniporter protein, mitochondrial",GO:0005262; GO:0019722; GO:0051561; GO:0042593; GO:0016021; GO:0006851; GO:0005743; GO:0032024; GO:0035786,calcium channel activity; calcium-mediated signaling; elevation of mitochondrial calcium ion concentration; glucose homeostasis; integral to membrane; mitochondrial calcium ion transport; mitochondrial inner membrane; positive regulation of insulin secretion; protein complex oligomerization,PF04678;,2.00E-20,CHOYP_SYFA.1.1,,,,,,,MCU_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament organization [GO:0007015]; calcium ion transmembrane import into mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0035786]; regulation of heart contraction [GO:0008016] comp99342_c0_seq3,837,41.9355,0.81623493,0,0,,2.00E-73,Q08BI9,"Calcium uniporter protein, mitochondrial (Coiled-coil domain-containing protein 109A)","Calcium uniporter protein, mitochondrial",GO:0005262; GO:0019722; GO:0051561; GO:0042593; GO:0016021; GO:0006851; GO:0005743; GO:0032024; GO:0035786,calcium channel activity; calcium-mediated signaling; elevation of mitochondrial calcium ion concentration; glucose homeostasis; integral to membrane; mitochondrial calcium ion transport; mitochondrial inner membrane; positive regulation of insulin secretion; protein complex oligomerization,PF04678;,,,,,,,,,MCU_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),actin filament organization [GO:0007015]; calcium ion transmembrane import into mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0035786]; regulation of heart contraction [GO:0008016] comp99354_c1_seq1,458,47.1616,0.5976591,1,4,,4.00E-68,P35992,Tyrosine-protein phosphatase 10D (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D),Tyrosine-protein phosphatase 10D (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D),GO:0045177; GO:0030424; GO:0007417; GO:0016021; GO:0007616; GO:0008045; GO:0007424; GO:0005886; GO:0005001,apical part of cell; axon; central nervous system development; integral to membrane; long-term memory; motor neuron axon guidance; open tracheal system development; plasma membrane; transmembrane receptor protein tyrosine phosphatase activity,PF00041;PF00102;,3.00E-57,CHOYP_PTPRB.2.4,,,,,,,PTP10_DROME,Drosophila melanogaster (Fruit fly),axon guidance [GO:0007411]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470] comp99354_c1_seq2,377,45.8886,0.51980564,0,0,,9.00E-24,P28203,Tyrosine-protein phosphatase 11 (EC 3.1.3.48) (Fragment),Tyrosine-protein phosphatase 11 (EC 3.1.3.48) (Fragment),GO:0035335; GO:0004725,peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity,PF00102;,3.00E-12,CHOYP_PTPRF.5.6,5.00E-13,ruditapes_c25768,,,,,PTP11_STYPL,Styela plicata (Wrinkled sea squirt) (Ascidia plicata), comp99355_c0_seq1,253,45.4545,0.62524054,4,0,,,,,,,,,1.00E-27,CHOYP_contig_031349,,,,,,,,, comp99360_c0_seq1,335,42.3881,0.82759358,6,22,,,,,,,,,1.00E-60,CHOYP_LOC100370583.1.1,,,,,,,,, comp99360_c0_seq2,313,43.4505,0.77531656,9,13,,6.00E-19,O62846,cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11) (Fragment),cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11) (Fragment),GO:0005524; GO:0004691,ATP binding; cAMP-dependent protein kinase activity,PF00069;,,,,,,,,,KAPCG_MACMU,Macaca mulatta (Rhesus macaque), comp99360_c1_seq1,932,41.8455,0.59111496,15,47,,7.00E-150,Q90XF2,Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) (nPKC-iota),Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) (nPKC-iota),GO:0005524; GO:0034334; GO:0045217; GO:0005829; GO:0007502; GO:0048546; GO:0021744; GO:0035050; GO:0000132; GO:0016332; GO:0035556; GO:0031226; GO:0045199; GO:0008078; GO:0001738; GO:0001841; GO:0007405; GO:0007097; GO:0005634; GO:0042476; GO:0005543; GO:0004697; GO:0004674; GO:0060042; GO:0008270; GO:0005915,ATP binding; adherens junction maintenance; cell-cell junction maintenance; cytosol; digestive tract mesoderm development; digestive tract morphogenesis; dorsal motor nucleus of vagus nerve development; embryonic heart tube development; establishment of mitotic spindle orientation; establishment or maintenance of polarity of embryonic epithelium; intracellular signal transduction; intrinsic to plasma membrane; maintenance of epithelial cell apical/basal polarity; mesodermal cell migration; morphogenesis of a polarized epithelium; neural tube formation; neuroblast proliferation; nuclear migration; nucleus; odontogenesis; phospholipid binding; protein kinase C activity; protein serine/threonine kinase activity; retina morphogenesis in camera-type eye; zinc ion binding; zonula adherens,PF00130;PF00564;PF00069;PF00433;,2.00E-133,CHOYP_LOC100533284.1.2,,,,,,,KPCI_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),adherens junction maintenance [GO:0034334]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cell-cell junction maintenance [GO:0045217]; cell-cell junction organization [GO:0045216]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dorsal motor nucleus of vagus nerve development [GO:0021744]; embryonic heart tube development [GO:0035050]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; generation of neurons [GO:0048699]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; mesodermal cell migration [GO:0008078]; morphogenesis of a polarized epithelium [GO:0001738]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; nuclear migration [GO:0007097]; odontogenesis [GO:0042476]; peptidyl-serine phosphorylation [GO:0018105]; photoreceptor cell outer segment organization [GO:0035845]; pronephric nephron tubule epithelial cell differentiation [GO:0035778]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042] comp99376_c0_seq1,491,49.6945,0.48851266,11,29,,9.00E-53,A2BGR3,DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like),DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like),GO:0005524; GO:0003677; GO:0051301; GO:0000777; GO:0004386; GO:0016539; GO:0007067,ATP binding; DNA binding; cell division; condensed chromosome kinetochore; helicase activity; intein-mediated protein splicing; mitosis,PF00271;PF00176;,2.00E-54,CHOYP_LOC100373376.1.1,,,,,,,ERC6L_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539]; mitotic nuclear division [GO:0007067] comp99398_c1_seq1,740,40,0.60993344,43,22,,5.00E-43,Q7KRW1,Protein TRC8 homolog,Protein TRC8 homolog,GO:0005783; GO:0005789; GO:0016021; GO:0045926; GO:0007418; GO:0008270,endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; negative regulation of growth; ventral midline development; zinc ion binding,PF13705;PF13639;,8.00E-29,CHOYP_LOC100368162.1.1,,,,,,,TRC8_DROME,Drosophila melanogaster (Fruit fly),negative regulation of growth [GO:0045926]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ventral midline development [GO:0007418] comp99399_c0_seq1,376,45.4787,0.31994569,15,36,,5.00E-30,Q91W90,Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46),Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46),GO:0045454; GO:0005788; GO:0006662; GO:0016853; GO:0015035,cell redox homeostasis; endoplasmic reticulum lumen; glycerol ether metabolic process; isomerase activity; protein disulfide oxidoreductase activity,PF00085;,,,,,,,,,TXND5_MOUSE,Mus musculus (Mouse),apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] comp99399_c0_seq2,202,49.505,0.57671868,5,0,,2.00E-08,P14949,Thioredoxin (Trx),Thioredoxin (Trx),GO:0045454; GO:0006662; GO:0015035,cell redox homeostasis; glycerol ether metabolic process; protein disulfide oxidoreductase activity,PF00085;,,,,,,,,,THIO_BACSU,Bacillus subtilis (strain 168),cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103] comp99405_c0_seq1,393,47.0738,0.75048105,25,6,,1.00E-39,Q5VZK9,Leucine-rich repeat-containing protein 16A (CARMIL homolog),"F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)",GO:0007015; GO:0007596; GO:0016477; GO:0005829; GO:0030027; GO:0030032; GO:0005634; GO:0031529; GO:0046415,actin filament organization; blood coagulation; cell migration; cytosol; lamellipodium; lamellipodium assembly; nucleus; ruffle organization; urate metabolic process,PF16000;PF13516;,5.00E-34,CHOYP_LR16A.3.3,,,,,,,LR16A_HUMAN,Homo sapiens (Human),actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415] comp99411_c0_seq1,211,42.1801,0.65232234,4,27,,2.00E-07,Q12899,Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173),Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173),GO:0003677; GO:0005737; GO:0046872; GO:0008270,DNA binding; cytoplasm; metal ion binding; zinc ion binding,PF13765;PF00622;PF00643;,,,,,,,,,TRI26_HUMAN,Homo sapiens (Human),innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091] comp99416_c0_seq1,458,43.0131,0.94737294,4,44,,1.00E-23,Q9H1P6,Uncharacterized protein C20orf85,Uncharacterized protein C20orf85,,,PF14945;,7.00E-14,CHOYP_LOC577148.1.1,2.00E-26,ruditapes_c10960,,,,,CT085_HUMAN,Homo sapiens (Human), comp99434_c1_seq1,316,46.8354,1.16118379,8,7,,3.00E-06,P20702,"Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)","Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)",GO:0007596; GO:0007155; GO:0051607; GO:0009897; GO:0030198; GO:0008305; GO:0007229; GO:0050900; GO:0046872; GO:0009887; GO:0004872,blood coagulation; cell adhesion; defense response to virus; external side of plasma membrane; extracellular matrix organization; integrin complex; integrin-mediated signaling pathway; leukocyte migration; metal ion binding; organ morphogenesis; receptor activity,PF01839;PF00357;PF08441;PF00092;,,,,,,,,,ITAX_HUMAN,Homo sapiens (Human),cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; organ morphogenesis [GO:0009887]; positive regulation of protein targeting to mitochondrion [GO:1903955] comp99443_c0_seq2,614,44.4625,0.49805769,15,45,,4.00E-69,A4IIL4,BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein),BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein),GO:0016020,membrane,PF03097;,5.00E-43,CHOYP_BRAFLDRAFT_115208.1.1,,,,,,,BROX_XENTR,Xenopus tropicalis (Western clawed frog) (Silurana tropicalis), comp99455_c0_seq1,311,44.373,0.86353884,0,0,,8.00E-12,Q9UHF1,Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1),Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1),GO:0001525; GO:0005509; GO:0005576; GO:0005615; GO:0045746; GO:0030336; GO:0001938; GO:0001570,angiogenesis; calcium ion binding; extracellular region; extracellular space; negative regulation of Notch signaling pathway; negative regulation of cell migration; positive regulation of endothelial cell proliferation; vasculogenesis,PF07974;PF07645;PF07546;,,,,,,,,,EGFL7_HUMAN,Homo sapiens (Human),angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; cell adhesion [GO:0007155]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of endothelial cell proliferation [GO:0001938]; vasculogenesis [GO:0001570] comp99455_c0_seq2,314,43.949,0.87500887,0,3,,2.00E-25,O75095,Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3),GO:0005509; GO:0005576,calcium ion binding; extracellular region,PF07645;PF00053;,,,,,,,,,MEGF6_HUMAN,Homo sapiens (Human), comp99459_c0_seq1,375,46.1333,0.61204993,14,0,,1.00E-06,Q5R5M4,Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9),Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9),GO:0016021; GO:0005886; GO:0015293,integral to membrane; plasma membrane; symporter activity,PF07690;,,,,,,,,,MOT9_PONAB,Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), comp99466_c0_seq1,470,40.2128,0.37045112,0,0,,,,,,,,,2.00E-28,CHOYP_ISCW_ISCW008626.1.1,,,,,,,,, comp99466_c0_seq3,352,42.6136,0.3771398,0,0,,1.00E-09,A6H7A8,Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1),Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1),GO:0005634,nucleus,,,,,,,,,,TDIF1_BOVIN,Bos taurus (Bovine),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp99472_c0_seq1,529,40.6427,0.69335674,3,58,,5.00E-38,Q14289,Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK),Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK),GO:0005524; GO:0000165; GO:0042976; GO:0032863; GO:0006915; GO:0030424; GO:0043534; GO:0045453; GO:0005938; GO:0071300; GO:0070098; GO:0005829; GO:0007204; GO:0007173; GO:0005925; GO:0048041; GO:0014009; GO:0030426; GO:0007229; GO:0030027; GO:0002315; GO:0045121; GO:0043066; GO:0030502; GO:0008285; GO:0045638; GO:0043267; GO:0031175; GO:0004715; GO:0005634; GO:0001556; GO:0048471; GO:0005886; GO:2000538; GO:0070374; GO:0046330; GO:0043507; GO:0030838; GO:0045766; GO:0030307; GO:0008284; GO:0001954; GO:0010595; GO:0010976; GO:0051000; GO:0050731; GO:0043552; GO:2000060; GO:2000379; GO:0045727; GO:0014069; GO:0046777; GO:2000249; GO:0030826; GO:0010752; GO:0050848; GO:0008360; GO:2000114; GO:0032960; GO:0010758; GO:0045428; GO:2000058; GO:0051279; GO:0051591; GO:0051592; GO:0042220; GO:0042493; GO:0045471; GO:0009749; GO:0009725; GO:0042542; GO:0001666; GO:0010226; GO:0009612; GO:0006970; GO:0006950; GO:0007172; GO:0004871; GO:0002040; GO:0043149; GO:0033209; GO:0048010,ATP binding; MAPK cascade; activation of Janus kinase activity; activation of Rac GTPase activity; apoptotic process; axon; blood vessel endothelial cell migration; bone resorption; cell cortex; cellular response to retinoic acid; chemokine-mediated signaling pathway; cytosol; elevation of cytosolic calcium ion concentration; epidermal growth factor receptor signaling pathway; focal adhesion; focal adhesion assembly; glial cell proliferation; growth cone; integrin-mediated signaling pathway; lamellipodium; marginal zone B cell differentiation; membrane raft; negative regulation of apoptotic process; negative regulation of bone mineralization; negative regulation of cell proliferation; negative regulation of myeloid cell differentiation; negative regulation of potassium ion transport; neuron projection development; non-membrane spanning protein tyrosine kinase activity; nucleus; oocyte maturation; perinuclear region of cytoplasm; plasma membrane; positive regulation of B cell chemotaxis; positive regulation of ERK1 and ERK2 cascade; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of actin filament polymerization; positive regulation of angiogenesis; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of cell-matrix adhesion; positive regulation of endothelial cell migration; positive regulation of neuron projection development; positive regulation of nitric-oxide synthase activity; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of reactive oxygen species metabolic process; positive regulation of translation; postsynaptic density; protein autophosphorylation; regulation of actin cytoskeleton reorganization; regulation of cGMP biosynthetic process; regulation of cGMP-mediated signaling; regulation of calcium-mediated signaling; regulation of cell shape; regulation of establishment of cell polarity; regulation of inositol trisphosphate biosynthetic process; regulation of macrophage chemotaxis; regulation of nitric oxide biosynthetic process; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of release of sequestered calcium ion into cytosol; response to cAMP; response to calcium ion; response to cocaine; response to drug; response to ethanol; response to glucose stimulus; response to hormone stimulus; response to hydrogen peroxide; response to hypoxia; response to lithium ion; response to mechanical stimulus; response to osmotic stress; response to stress; signal complex assembly; signal transducer activity; sprouting angiogenesis; stress fiber assembly; tumor necrosis factor-mediated signaling pathway; vascular endothelial growth factor receptor signaling pathway,PF00373;PF03623;PF07714;,3.00E-82,CHOYP_LOC100876637.2.2,,,,,,,FAK2_HUMAN,Homo sapiens (Human),"activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein complex assembly [GO:0006461]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP biosynthetic process [GO:0030826]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; response to stress [GO:0006950]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]" comp99472_c0_seq2,321,42.6791,0.55043269,0,4,,,,,,,,,3.00E-29,CHOYP_LOC100118485.1.1,,,,,,,,, comp99496_c0_seq1,510,42.1569,0.46244522,37,58,,7.00E-47,Q9EP80,PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein),PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein),GO:0016887; GO:0035256; GO:0051020; GO:0005794; GO:0030425; GO:0015872; GO:0046875; GO:0042802; GO:0046872; GO:0048471; GO:0014069; GO:0042734; GO:0008022; GO:0043234; GO:0019904; GO:0005080; GO:0007205; GO:0006468; GO:0043113; GO:0030971,ATPase activity; G-protein coupled glutamate receptor binding; GTPase binding; Golgi apparatus; dendrite; dopamine transport; ephrin receptor binding; identical protein binding; metal ion binding; perinuclear region of cytoplasm; postsynaptic density; presynaptic membrane; protein C-terminus binding; protein complex; protein domain specific binding; protein kinase C binding; protein kinase C-activating G-protein coupled receptor signaling pathway; protein phosphorylation; receptor clustering; receptor tyrosine kinase binding,PF06456;PF00595;,3.00E-82,CHOYP_LOC100370426.1.2,,,,,,,PICK1_RAT,Rattus norvegicus (Rat),cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; dopamine transport [GO:0015872]; glial cell development [GO:0021782]; long term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; receptor clustering [GO:0043113] comp99510_c0_seq1,318,44.6541,0.50786572,7,5,,3.00E-36,Q6DDF0,WD repeat-containing protein 37,WD repeat-containing protein 37,,,PF00400;,1.00E-22,CHOYP_WDR37.1.1,,,,,,,WDR37_XENLA,Xenopus laevis (African clawed frog), comp99520_c0_seq1,493,38.3367,0.27752923,12,34,,8.00E-10,O61967,Protein lap1 (Lethal protein 413),Protein lap1 (Lethal protein 413),GO:0030029; GO:0005912; GO:0016323; GO:0007155; GO:0007043; GO:0009790; GO:0007163; GO:0015031; GO:0045108,actin filament-based process; adherens junction; basolateral plasma membrane; cell adhesion; cell-cell junction assembly; embryo development; establishment or maintenance of cell polarity; protein transport; regulation of intermediate filament polymerization or depolymerization,PF13855;PF00595;,,,,,,,,,LAP1_CAEEL,Caenorhabditis elegans,actin filament-based process [GO:0030029]; cell adhesion [GO:0007155]; cell-cell junction assembly [GO:0007043]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract morphogenesis [GO:0048557]; establishment or maintenance of cell polarity [GO:0007163]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein transport [GO:0015031]; regulation of intermediate filament polymerization or depolymerization [GO:0045108] comp99522_c0_seq1,509,40.8644,0.14370301,11,32,,9.00E-66,Q5ZMT7,Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-),Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-),GO:0005524; GO:0005576; GO:0004674,ATP binding; extracellular region; protein serine/threonine kinase activity,PF03109;,4.00E-75,CHOYP_LOC100369003.2.2,,,,,,,ADCK1_CHICK,Gallus gallus (Chicken), comp99547_c0_seq2,521,42.2265,0.64844959,0,0,,,,,,,,,4.00E-11,CHOYP_BRAFLDRAFT_225147.1.1,,,,,,,,, comp99547_c0_seq3,571,40.9807,0.62696575,0,10,,5.00E-16,Q8R512,UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5),UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5),GO:0005737; GO:0005856,cytoplasm; cytoskeleton,PF08059;PF00789;,5.00E-11,CHOYP_BRAFLDRAFT_225147.1.1,,,,,,,UBX11_RAT,Rattus norvegicus (Rat),proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] comp99550_c0_seq1,229,60.6987,0.95477122,0,9,,1.00E-16,P10346,Glutamine transport ATP-binding protein GlnQ,Glutamine transport ATP-binding protein GlnQ,GO:0005524; GO:0006200; GO:0016887; GO:0006865; GO:0005886,ATP binding; ATP catabolic process; ATPase activity; amino acid transport; plasma membrane,PF00005;,,,,,,,,,GLNQ_ECOLI,Escherichia coli (strain K12), comp99556_c0_seq1,536,41.4179,0.70559497,26,0,,2.00E-16,E9Q555,E3 ubiquitin-protein ligase RNF213 (EC 6.3.2.-),E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213),GO:0016887; GO:0005737; GO:0000166; GO:0051865; GO:0004842; GO:0008270,ATPase activity; cytoplasm; nucleotide binding; protein autoubiquitination; ubiquitin-protein ligase activity; zinc ion binding,,,,,,,,,,RN213_MOUSE,Mus musculus (Mouse),angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511] comp99559_c0_seq1,832,46.6346,0.4022541,35,60,,8.00E-40,Q9JHS4,"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial","ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial",GO:0005524; GO:0004176; GO:0016887; GO:0046872; GO:0009841; GO:0005743; GO:0042645; GO:0016504; GO:0006457; GO:0051603,ATP binding; ATP-dependent peptidase activity; ATPase activity; metal ion binding; mitochondrial endopeptidase Clp complex; mitochondrial inner membrane; mitochondrial nucleoid; peptidase activator activity; protein folding; proteolysis involved in cellular protein catabolic process,PF07724;PF10431;,,,,,,,,,CLPX_MOUSE,Mus musculus (Mouse),protein catabolic process [GO:0030163]; protein folding [GO:0006457]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603] comp99574_c0_seq1,246,62.1951,1.11844412,0,9,,7.00E-17,Q84HD6,Amylosucrase (EC 2.4.1.4),Amylosucrase (EC 2.4.1.4),GO:0047669; GO:0005975; GO:0043169; GO:0005576,amylosucrase activity; carbohydrate metabolic process; cation binding; extracellular region,PF00128;,,,,,,,,,AMYS_NEIME,Neisseria meningitidis,carbohydrate metabolic process [GO:0005975] comp99577_c1_seq1,312,46.1538,0.97281497,0,44,,1.00E-11,O70582,"Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (Epidermis-type lipoxygenase 2) (e-LOX 2)","Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (Epidermis-type lipoxygenase 2) (e-LOX 2)",GO:0004052; GO:0019369; GO:0046513; GO:0005737; GO:0061436; GO:0051122; GO:0005506; GO:1990136; GO:0043651; GO:0019372; GO:0043410; GO:0010628; GO:0070257; GO:0006497,arachidonate 12-lipoxygenase activity; arachidonic acid metabolic process; ceramide biosynthetic process; cytoplasm; establishment of skin barrier; hepoxilin biosynthetic process; iron ion binding; linoleate 9S-lipoxygenase activity; linoleic acid metabolic process; lipoxygenase pathway; positive regulation of MAPK cascade; positive regulation of gene expression; positive regulation of mucus secretion; protein lipidation,PF00305;PF01477;,,,,,,,,,LX12B_MOUSE,Mus musculus (Mouse),arachidonic acid metabolic process [GO:0019369]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipoxygenase pathway [GO:0019372]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; protein lipidation [GO:0006497]; sphingolipid metabolic process [GO:0006665] comp99584_c0_seq1,241,43.5685,0.79898661,11,0,,3.00E-26,Q04499,"Proline dehydrogenase 1, mitochondrial (EC 1.5.99.8) (Proline oxidase) (Protein sluggish-A)","Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Protein sluggish-A)",GO:0071949; GO:0006537; GO:0007626; GO:0005759; GO:0005739; GO:0042331; GO:0006562; GO:0010133; GO:0004657,FAD binding; glutamate biosynthetic process; locomotory behavior; mitochondrial matrix; mitochondrion; phototaxis; proline catabolic process; proline catabolic process to glutamate; proline dehydrogenase activity,PF01619;,1.00E-38,CHOYP_LOC101078914.1.1,,,,,,,PROD_DROME,Drosophila melanogaster (Fruit fly),glutamate biosynthetic process [GO:0006537]; locomotory behavior [GO:0007626]; phototaxis [GO:0042331]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133] comp99599_c0_seq1,226,49.5575,0.96597636,0,40,,,,,,,,,3.00E-40,CHOYP_LOC100501556.1.1,,,,,,,,, comp99603_c0_seq1,450,41.3333,0.47066559,6,47,,2.00E-54,Q92696,Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha),Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha),GO:0004663; GO:0006464; GO:0018344; GO:0007601; GO:0008270,Rab geranylgeranyltransferase activity; cellular protein modification process; protein geranylgeranylation; visual perception; zinc ion binding,PF01239;PF07711;,7.00E-33,CHOYP_PGTA.1.1,,,,,,,PGTA_HUMAN,Homo sapiens (Human),cellular protein modification process [GO:0006464]; protein geranylgeranylation [GO:0018344]; regulation of apoptotic process [GO:0042981]; visual perception [GO:0007601] comp99604_c1_seq1,1459,45.4421,0.73211683,30,103,,3.00E-33,Q9ES67,Rho guanine nucleotide exchange factor 11 (RhoGEF glutamate transport modulator GTRAP48),Rho guanine nucleotide exchange factor 11 (RhoGEF glutamate transport modulator GTRAP48),GO:0005096; GO:0005089; GO:0005737; GO:0035556; GO:0016020; GO:0005543; GO:0043547; GO:0035023; GO:0001505; GO:0038032,GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; cytoplasm; intracellular signal transduction; membrane; phospholipid binding; positive regulation of GTPase activity; regulation of Rho protein signal transduction; regulation of neurotransmitter levels; termination of G-protein coupled receptor signaling pathway,PF00595;PF09128;PF00621;,,,,,,,,,ARHGB_RAT,Rattus norvegicus (Rat),G-protein coupled receptor signaling pathway [GO:0007186]; regulation of neurotransmitter levels [GO:0001505]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266] comp99630_c1_seq1,258,40.3101,0.39021302,3,15,,,,,,,,,3.00E-15,CHOYP_MGG_06113.1.1,,,,,,,,, comp99640_c0_seq2,391,43.2225,0.67123727,10,25,,7.00E-62,P51955,Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1),Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1),GO:0005524; GO:0000086; GO:0001824; GO:0051301; GO:0005813; GO:0051299; GO:0007059; GO:0000777; GO:0000794; GO:0005829; GO:0000776; GO:0007126; GO:0046872; GO:0005874; GO:0030496; GO:0007067; GO:0000070; GO:0043392; GO:0005730; GO:0046777; GO:0004674; GO:0051988; GO:0046602; GO:0051225; GO:0090307; GO:0000922,ATP binding; G2/M transition of mitotic cell cycle; blastocyst development; cell division; centrosome; centrosome separation; chromosome segregation; condensed chromosome kinetochore; condensed nuclear chromosome; cytosol; kinetochore; meiosis; metal ion binding; microtubule; midbody; mitosis; mitotic sister chromatid segregation; negative regulation of DNA binding; nucleolus; protein autophosphorylation; protein serine/threonine kinase activity; regulation of attachment of spindle microtubules to kinetochore; regulation of mitotic centrosome separation; spindle assembly; spindle assembly involved in mitosis; spindle pole,PF00069;,3.00E-49,CHOYP_NEK2.2.3,,,,,,,NEK2_HUMAN,Homo sapiens (Human),blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] comp99658_c0_seq1,493,46.0446,0.38354195,9,48,,5.00E-24,Q8IZ52,Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2),Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2),GO:0032580; GO:0000139; GO:0050510; GO:0005975; GO:0030206; GO:0047238; GO:0016021; GO:0046872; GO:0016758,"Golgi cisterna membrane; Golgi membrane; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; integral to membrane; metal ion binding; transferase activity, transferring hexosyl groups",PF05679;,,,,,,,,,CHSS2_HUMAN,Homo sapiens (Human),chondroitin sulfate biosynthetic process [GO:0030206] comp99678_c0_seq1,482,43.7759,0.53547902,7,46,,4.00E-20,E2QUI9,ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein),ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase),GO:0005524; GO:0047453; GO:0005739,ATP binding; ATP-dependent NAD(P)H-hydrate dehydratase activity; mitochondrion,PF01256;,8.00E-14,CHOYP_PC11X.1.2,,,,,,,NNRD_CANFA,Canis lupus familiaris (Dog) (Canis familiaris),nicotinamide nucleotide metabolic process [GO:0046496] comp99698_c0_seq1,333,32.4324,0.81181288,5,38,,4.00E-23,Q14585,Zinc finger protein 345 (Zinc finger protein HZF10),Zinc finger protein 345 (Zinc finger protein HZF10),GO:0003677; GO:0046872; GO:0000122; GO:0005634; GO:0006359; GO:0006366; GO:0006383,DNA binding; metal ion binding; negative regulation of transcription from RNA polymerase II promoter; nucleus; regulation of transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter,PF00096;PF13912;PF13465;,,,,,,,,,ZN345_HUMAN,Homo sapiens (Human),negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366] comp99725_c0_seq1,569,45.6942,0.50893014,15,8,,3.00E-37,Q5M868,Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2),Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2),GO:0000139; GO:0008422; GO:0008206; GO:0021954; GO:0005789; GO:0004348; GO:0006680; GO:0016139; GO:0016021,Golgi membrane; beta-glucosidase activity; bile acid metabolic process; central nervous system neuron development; endoplasmic reticulum membrane; glucosylceramidase activity; glucosylceramide catabolic process; glycoside catabolic process; integral to membrane,PF04685;PF12215;,,,,,,,,,GBA2_RAT,Rattus norvegicus (Rat),bile acid metabolic process [GO:0008206]; central nervous system neuron development [GO:0021954]; glucosylceramide catabolic process [GO:0006680]; glycoside catabolic process [GO:0016139] comp99725_c0_seq2,422,43.128,0.56744221,3,0,,7.00E-09,Q7KT91,Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45),Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45),GO:0008422; GO:0008206; GO:0004348; GO:0006680; GO:0016139; GO:0016021; GO:0005886,beta-glucosidase activity; bile acid metabolic process; glucosylceramidase activity; glucosylceramide catabolic process; glycoside catabolic process; integral to membrane; plasma membrane,PF04685;PF12215;,,,,,,,,,C3390_DROME,Drosophila melanogaster (Fruit fly),bile acid metabolic process [GO:0008206]; glycoside catabolic process [GO:0016139]; sphingolipid metabolic process [GO:0006665] comp99731_c0_seq1,787,41.5502,0.41355592,25,55,,2.00E-25,Q8IWB9,Testis-expressed sequence 2 protein (Transmembrane protein 96),Testis-expressed sequence 2 protein (Transmembrane protein 96),GO:0016021; GO:0005543; GO:0007165; GO:0006665,integral to membrane; phospholipid binding; signal transduction; sphingolipid metabolic process,,,,,,,,,,TEX2_HUMAN,Homo sapiens (Human),signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665] comp99732_c0_seq1,271,50.9225,0.88370274,6,0,,,,,,,,,4.00E-21,CHOYP_NEMVEDRAFT_V1G210732.1.1,,,,,,,,, comp99768_c1_seq1,459,44.2266,0.31906612,15,18,,4.00E-35,Q62824,Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8),Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8),GO:0055108; GO:0030165; GO:0043198; GO:0030010; GO:0000145; GO:0030426; GO:0044091; GO:0043209; GO:0043025; GO:0048709; GO:0050850; GO:0014069; GO:0032403; GO:0006612; GO:0051223; GO:0007268; GO:0006904; GO:0006903,Golgi to transport vesicle transport; PDZ domain binding; dendritic shaft; establishment of cell polarity; exocyst; growth cone; membrane biogenesis; myelin sheath; neuronal cell body; oligodendrocyte differentiation; positive regulation of calcium-mediated signaling; postsynaptic density; protein complex binding; protein targeting to membrane; regulation of protein transport; synaptic transmission; vesicle docking involved in exocytosis; vesicle targeting,PF04048;,4.00E-36,CHOYP_EXOC4.1.2,,,,,,,EXOC4_RAT,Rattus norvegicus (Rat),chemical synaptic transmission [GO:0007268]; establishment of cell polarity [GO:0030010]; Golgi to transport vesicle transport [GO:0055108]; membrane biogenesis [GO:0044091]; oligodendrocyte differentiation [GO:0048709]; positive regulation of calcium-mediated signaling [GO:0050850]; protein targeting to membrane [GO:0006612]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903] comp99769_c0_seq1,1229,37.3474,0.94980758,10,143,,5.00E-91,Q8X119,Actin,Actin,GO:0005524; GO:0005737; GO:0005856,ATP binding; cytoplasm; cytoskeleton,PF00022;,,,,,,,,,ACT_EXODE,Exophiala dermatitidis (Black yeast) (Wangiella dermatitidis), comp99776_c0_seq1,1527,45.2521,0.51748392,70,122,,1.00E-146,P27808,"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)","Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)",GO:0000139; GO:0006049; GO:0008375; GO:0003827; GO:0001701; GO:0016021; GO:0046872; GO:0006486,"Golgi membrane; UDP-N-acetylglucosamine catabolic process; acetylglucosaminyltransferase activity; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity; in utero embryonic development; integral to membrane; metal ion binding; protein glycosylation",PF03071;,2.00E-97,CHOYP_LOC100559184.1.1,,,,,,,MGAT1_MOUSE,Mus musculus (Mouse),in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; UDP-N-acetylglucosamine catabolic process [GO:0006049] comp99783_c0_seq1,347,33.1412,0.31636626,9,48,,,,,,,,,7.00E-13,CHOYP_LOC100870108.2.4,,,,,,,,, comp99786_c0_seq1,395,49.8734,0.82569337,3,71,,2.00E-16,A8WHP3,Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9),GO:0016021; GO:0006814; GO:0055085; GO:0005215,integral to membrane; sodium ion transport; transmembrane transport; transporter activity,PF00474;,,,,,,,,,SC5A9_DANRE,Danio rerio (Zebrafish) (Brachydanio rerio),sodium ion transport [GO:0006814] comp99794_c0_seq1,294,45.9184,0.73350758,0,43,,3.00E-09,Q6GNV7,Disrupted in renal carcinoma protein 2 homolog,Disrupted in renal carcinoma protein 2 homolog,GO:0016021; GO:0005765; GO:0055085,integral to membrane; lysosomal membrane; transmembrane transport,PF07690;,,,,,,,,,DIRC2_XENLA,Xenopus laevis (African clawed frog),transmembrane transport [GO:0055085] comp99807_c0_seq1,511,40.5088,0.48623168,30,29,,3.00E-09,P18722,Gastrula zinc finger protein XlCGF46.1 (Fragment),Gastrula zinc finger protein XlCGF46.1 (Fragment),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,ZG46_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp99829_c0_seq1,507,42.2091,0.74127055,20,29,,6.00E-33,Q9NQZ5,"StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7)","StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7)",GO:0008289; GO:0005739,lipid binding; mitochondrion,PF01852;,,,,,,,,,STAR7_HUMAN,Homo sapiens (Human),positive regulation of protein targeting to mitochondrion [GO:1903955] comp99849_c0_seq1,397,41.8136,0.57984051,13,4,,2.00E-24,Q9H3U1,Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1),Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1),GO:0030154; GO:0061077; GO:0007517; GO:0005634; GO:0048471,cell differentiation; chaperone-mediated protein folding; muscle organ development; nucleus; perinuclear region of cytoplasm,PF13181;PF11701;,9.00E-12,CHOYP_ISCW_ISCW018499.1.1,,,,,,,UN45A_HUMAN,Homo sapiens (Human),cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517] comp9984_c0_seq1,355,47.0423,0.35753512,10,0,,4.00E-51,Q6P423,Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23),Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23),GO:0005634; GO:0006355; GO:0006351,"nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF11573;,1.00E-53,CHOYP_MED23.1.1,,,,,,,MED23_XENLA,Xenopus laevis (African clawed frog),"regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]" comp99853_c1_seq1,270,32.963,0.83385759,0,19,,,,,,,,,,,1.00E-11,ruditapes_lrc37813,,,,,,, comp99866_c0_seq1,385,41.8182,0.36773827,17,39,,6.00E-63,P35241,Radixin,Radixin,GO:0051693; GO:0045177; GO:0045176; GO:0032154; GO:0005737; GO:0005856; GO:0019898; GO:0030175; GO:0030027; GO:0030033; GO:0005886; GO:0001726; GO:0032420,actin filament capping; apical part of cell; apical protein localization; cleavage furrow; cytoplasm; cytoskeleton; extrinsic to membrane; filopodium; lamellipodium; microvillus assembly; plasma membrane; ruffle; stereocilium,PF00769;PF09380;PF00373;PF09379;,9.00E-63,CHOYP_MERL.1.1,,,,,,,RADI_HUMAN,Homo sapiens (Human),actin filament capping [GO:0051693]; apical protein localization [GO:0045176]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; establishment of protein localization to plasma membrane [GO:0090002]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein kinase A signaling [GO:0010737]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of Rap protein signal transduction [GO:0032487]; regulation of ruffle assembly [GO:1900027] comp99880_c0_seq1,374,49.4652,0.48724657,10,3,,3.00E-49,Q9Y666,Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4),Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4),GO:0006884; GO:0005887; GO:0006813; GO:0015379,cell volume homeostasis; integral to plasma membrane; potassium ion transport; potassium:chloride symporter activity,PF00324;PF03522;,7.00E-45,CHOYP_DWIL_GK15715.1.1,,,,,,,S12A7_HUMAN,Homo sapiens (Human),cell volume homeostasis [GO:0006884]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; transport [GO:0006810] comp99891_c0_seq1,397,39.5466,0.78218642,9,52,,1.00E-12,Q99M85,Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt),Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt),GO:0003677; GO:0046872; GO:0005634; GO:0006355; GO:0006351,"DNA binding; metal ion binding; nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent",PF00096;PF13912;,,,,,,,,,SCRT1_MOUSE,Mus musculus (Mouse),"negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; transcription, DNA-templated [GO:0006351]" comp99895_c0_seq1,279,48.0287,0.56757486,0,0,,1.00E-16,Q683D5,U-box domain-containing protein 37 (EC 6.3.2.-) (Plant U-box protein 37),U-box domain-containing protein 37 (EC 6.3.2.-) (Plant U-box protein 37),GO:0000151; GO:0004842,ubiquitin ligase complex; ubiquitin-protein ligase activity,PF04564;,,,3.00E-33,ruditapes_c13088,,,,,PUB37_ARATH,Arabidopsis thaliana (Mouse-ear cress), comp99895_c0_seq2,819,46.1538,0.37383233,18,47,,8.00E-52,Q5FVN8,"WD repeat, SAM and U-box domain-containing protein 1","WD repeat, SAM and U-box domain-containing protein 1",GO:0000151; GO:0004842,ubiquitin ligase complex; ubiquitin-protein ligase activity,PF07647;PF04564;PF00400;,1.00E-14,CHOYP_LOC100893535.1.1,,,,,,,WSDU1_RAT,Rattus norvegicus (Rat), comp99904_c1_seq1,231,38.961,0.34644751,6,0,,,,,,,,,,,4.00E-11,ruditapes_c4344,,,,,,, comp99916_c0_seq1,206,49.0291,0.64942707,1,34,,9.00E-22,P51840,Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E),Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E),GO:0005524; GO:0005525; GO:0004383; GO:0016021; GO:0035556; GO:0005886; GO:0004672; GO:0007601,ATP binding; GTP binding; guanylate cyclase activity; integral to membrane; intracellular signal transduction; plasma membrane; protein kinase activity; visual perception,PF01094;PF00211;PF07701;PF07714;,4.00E-26,CHOYP_ANPRB.2.2,4.00E-17,ruditapes_c18064,,,,,GUC2E_RAT,Rattus norvegicus (Rat),cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; visual perception [GO:0007601] comp99922_c0_seq1,812,44.9507,0.37739118,32,91,,2.00E-43,Q9BY27,Protein DGCR6L (DiGeorge syndrome critical region 6-like protein),Protein DGCR6L (DiGeorge syndrome critical region 6-like protein),GO:0005634,nucleus,PF07324;,1.00E-58,CHOYP_DGC6L.1.1,,,,,,,DGC6L_HUMAN,Homo sapiens (Human), comp99943_c0_seq1,345,42.6087,0.44885477,4,35,,1.00E-20,D2GXS7,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,,,,,,,,,TRIM2_AILME,Ailuropoda melanoleuca (Giant panda),regulation of neuron apoptotic process [GO:0043523] comp99943_c1_seq2,470,42.1277,0.5560828,5,11,,7.00E-40,A4IF63,Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2),GO:0005737; GO:0043523; GO:0004842; GO:0008270,cytoplasm; regulation of neuron apoptotic process; ubiquitin-protein ligase activity; zinc ion binding,PF00630;PF01436;PF00643;PF13445;,4.00E-49,CHOYP_BRAFLDRAFT_69647.1.5,,,,,,,TRIM2_BOVIN,Bos taurus (Bovine),regulation of neuron apoptotic process [GO:0043523] comp99950_c0_seq1,255,44.3137,0.65307127,2,51,,5.00E-27,B2UGE9,Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C),Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C),GO:0006777,Mo-molybdopterin cofactor biosynthetic process,PF01967;,,,,,,,,,MOAC_RALPJ,Ralstonia pickettii (strain 12J),Mo-molybdopterin cofactor biosynthetic process [GO:0006777] comp99983_c1_seq1,595,42.0168,0.57348292,0,61,,2.00E-50,Q8K0Q5,Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18),Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18),GO:0005096; GO:0005622; GO:0043547; GO:0007165,GTPase activator activity; intracellular; positive regulation of GTPase activity; signal transduction,PF00620;,,,,,,,,,RHG18_MOUSE,Mus musculus (Mouse),regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] comp99986_c0_seq1,247,42.5101,0.64680643,6,0,,,,,,,,,1.00E-20,CHOYP_SAMH1.10.12,2.00E-14,ruditapes_c31016,,,,,,, comp99986_c2_seq1,261,42.5287,0.43320742,5,8,,6.00E-29,Q5ZJL9,Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-),Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-),GO:0003723; GO:0051607; GO:0045087; GO:0008152; GO:0046872; GO:0005634; GO:0008081; GO:0045088,RNA binding; defense response to virus; innate immune response; metabolic process; metal ion binding; nucleus; phosphoric diester hydrolase activity; regulation of innate immune response,PF01966;,,,6.00E-29,ruditapes_c985,,,,,SAMH1_CHICK,Gallus gallus (Chicken),dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; innate immune response [GO:0045087]; regulation of innate immune response [GO:0045088] comp99996_c0_seq1,242,57.8512,1.30647392,1,0,,1.00E-50,Q6A707,Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS),Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS),GO:0005524; GO:0005737; GO:0046872; GO:0004825; GO:0006431,ATP binding; cytoplasm; metal ion binding; methionine-tRNA ligase activity; methionyl-tRNA aminoacylation,PF08264;PF09334;,,,,,,,,,SYM_PROAC,Propionibacterium acnes (strain KPA171202 / DSM 16379),methionyl-tRNA aminoacylation [GO:0006431] comp99996_c2_seq1,212,63.6792,1.17190107,2,0,,3.00E-29,B9LDY3,Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS),Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS),GO:0005524; GO:0005737; GO:0046872; GO:0004825; GO:0006431,ATP binding; cytoplasm; metal ion binding; methionine-tRNA ligase activity; methionyl-tRNA aminoacylation,PF08264;PF09334;,,,,,,,,,SYM_CHLSY,Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl),methionyl-tRNA aminoacylation [GO:0006431]